Document:

EX-4.8

 Exhibit 4.8 

NOBLE ENERGY, INC. 
 to 

WELLS FARGO BANK, NATIONAL ASSOCIATION, 

as Trustee 
  

 
 Sixth
Supplemental Indenture 
 dated as of [            ], 2015 

to 
 Indenture 

dated as of February 27, 2009 
  

 
 $700,000,000
5.625% Senior Notes due 2021 
 $600,000,000 5.875% Senior Notes due 2022 

$500,000,000 5.875% Senior Notes due 2024 

 TABLE OF CONTENTS 

 

							
	 	  	 	  	Page	 
		
	 ARTICLE I RELATION TO INDENTURE; DEFINITIONS
	  	 	1	  
			
	 Section 1.01
	  	 Relation To Indenture
	  	 	1	  
			
	 Section 1.02
	  	 Rules of Interpretation; Definitions
	  	 	1	  
		
	 ARTICLE II THE SERIES OF DEBT SECURITIES
	  	 	1	  
			
	 Section 2.01
	  	 Title of the Debt Securities
	  	 	1	  
			
	 Section 2.02
	  	 Limitations on Aggregate Principal Amount
	  	 	2	  
			
	 Section 2.03
	  	 Registered Securities; Global Form
	  	 	2	  
			
	 Section 2.04
	  	 Forms and Terms of Notes
	  	 	2	  
			
	 Section 2.05
	  	 Registrar and Paying Agent
	  	 	2	  
			
	 Section 2.06
	  	 Applicability of Certain Indenture Provisions
	  	 	2	  
		
	 ARTICLE III MISCELLANEOUS PROVISIONS
	  	 	3	  
			
	 Section 3.01
	  	 Ratification of Indenture
	  	 	3	  
			
	 Section 3.02
	  	 Governing Law
	  	 	3	  
			
	 Section 3.03
	  	 Counterparts
	  	 	3	  
			
	 Section 3.04
	  	 Recitals
	  	 	3	  

  
 i 

 SIXTH SUPPLEMENTAL INDENTURE, dated as of
[            ], 2015 (this “Supplemental Indenture”), between NOBLE ENERGY, INC., a corporation duly organized and existing under the laws of the State of Delaware (the
“Company”), and WELLS FARGO BANK, NATIONAL ASSOCIATION, a national banking association, as trustee (the “Trustee”). 

RECITALS OF THE COMPANY 

WHEREAS, the Company has heretofore delivered to the Trustee an Indenture dated as of February 27, 2009, as amended and supplemented from
time to time (the “Indenture”), providing for the issuance from time to time of debt securities of the Company (the “Debt Securities”). 

WHEREAS, Section 3.01 of the Indenture provides that various matters with respect to any series of Debt Securities issued under the
Indenture may be established in an indenture supplemental to the Indenture. 
 WHEREAS, Section 12.01(f) of the Indenture provides for
the Company and the Trustee to enter into an indenture supplemental to the Indenture to establish the form or terms of Debt Securities of any series as contemplated by Sections 2.01 and 3.01 of the Indenture. 

WHEREAS, all the conditions and requirements necessary to make this Supplemental Indenture, when duly executed and delivered, a valid and
legally binding agreement in accordance with its terms and for the purposes herein expressed, have been performed and fulfilled. 
 NOW,
THEREFORE, THIS INDENTURE WITNESSETH: 
 For and in consideration of the premises and the purchase of the series of Debt Securities provided
for herein by the Holders thereof, it is mutually covenanted and agreed, for the equal and proportionate benefit of all Holders of the series of Debt Securities provided for herein, as follows: 

ARTICLE I 
 RELATION
TO INDENTURE; DEFINITIONS 
  

	 	Section 1.01	Relation To Indenture. 

 This Supplemental Indenture constitutes an integral part of the
Indenture. 
  

	 	Section 1.02	Rules of Interpretation; Definitions. 

 The first paragraph of Section 1.01 of the
Indenture is fully incorporated by reference into this Supplemental Indenture. For all purposes of this Supplemental Indenture, except as otherwise expressly provided or unless the context otherwise requires, capitalized terms used but not defined
herein shall have the respective meanings assigned to them in the Indenture. 
 ARTICLE II 

THE SERIES OF DEBT SECURITIES 
  

	 	Section 2.01	Title of the Debt Securities. 

 There is hereby created under the Indenture a series of
Debt Securities designated the “5.625% Senior Notes due 2021” (the “2021 Senior Notes”), “5.875% Senior Notes due 2022” (the “2022 Senior Notes”) and a series of Debt Securities designated the
“5.875% Notes due 2024” (the “2024 Senior Notes” and, collectively with the 2021 Senior Notes and the 2022 Senior Notes, the “Notes”). 

	 	Section 2.02	Limitations on Aggregate Principal Amount. 

 The aggregate principal amount of the 2021
Senior Notes shall be initially limited to $700,000,000, the aggregate principal amount of the 2022 Senior Notes shall be initially limited to $600,000,000 and the aggregate principal amount of the 2024 Senior Notes shall be initially limited to
$500,000,000; provided that the Company may, without the consent of the Holders of Outstanding Notes of a series, increase the principal amount of the Notes Outstanding of such series by issuing additional Notes (“Additional
Notes”) of such series in the future on the same terms and conditions (including, without limitation, the right to receive accrued and unpaid interest), except for differences in the issue price and issue date of the Additional Notes, and
with the same CUSIP number as the Notes then Outstanding of such series; provided that such Additional Notes of a series are fungible with previously issued Notes of such series for U.S. federal income tax purposes. No Additional Notes of a
series may be issued if an Event of Default has occurred and is continuing with respect to the Notes of such series. Any Additional Notes of a series shall rank equally and ratably with the Notes of such series then Outstanding and shall be treated
as a single series for all purposes hereunder and under the Indenture. From and after the issue date of any Additional Notes of a series, any reference herein to “Notes” shall include such Additional Notes of such series. 

Except as provided in this Section, the Company shall not execute and the Trustee shall not authenticate or deliver Notes of a series in
excess of the aggregate principal amount specified in the preceding paragraph. 
 Nothing contained in this Section 2.02 or elsewhere
in this Supplemental Indenture, or in the Notes, is intended to or shall limit execution by the Company or authentication or delivery by the Trustee of the Notes under the circumstances contemplated in Section 3.05, 3.06, 4.06 and 12.06 of the
Indenture. 
  

	 	Section 2.03	Registered Securities; Global Form. 

 The Notes shall be issuable and transferable in
fully registered form, without coupons. The Notes shall be issued in the form of one or more permanent Global Securities subject to any requirements of the Indenture for the issuance of definitive Notes in exchange therefor. The Depositary for the
Notes shall be The Depository Trust Company. Beneficial interests in the Global Securities evidencing the Notes of a series shall not be exchangeable for Notes of such series in definitive form except as provided in Section 2.03 of the
Indenture. 
  

	 	Section 2.04	Forms and Terms of Notes. 

 The 2021 Senior Notes shall be substantially in the form
attached as Exhibit A hereto and shall have the terms specified therein. The 2022 Senior Notes shall be substantially in the form attached as Exhibit B hereto and shall have the terms specified therein. The 2024 Senior Notes shall be
substantially in the form attached as Exhibit C hereto and shall have the terms specified therein. 
  

	 	Section 2.05	Registrar and Paying Agent. 

 The Trustee shall initially serve as Debt Security
Registrar and Paying Agent for the Notes. 
  

	 	Section 2.06	Applicability of Certain Indenture Provisions. 

 The provisions of Article VI of the
Indenture, including Section 6.06 thereof, shall be applicable to the Notes. The provisions of Article XIII of the Indenture relating to defeasance and covenant defeasance shall be applicable to the Notes. 

  
 2 

 ARTICLE III 

MISCELLANEOUS PROVISIONS 
  

	 	Section 3.01	Ratification of Indenture. 

 Except as expressly modified or amended hereby, the
Indenture continues in full force and effect and is in all respects confirmed and preserved. 
  

	 	Section 3.02	Governing Law. 

 This Supplemental Indenture and each Note shall be governed by and
construed in accordance with the laws of the State of New York. This Supplemental Indenture is subject to the provisions of the Trust Indenture Act of 1939, as amended, and shall, to the extent applicable, be governed by such provisions. 

 

	 	Section 3.03	Counterparts. 

 This Supplemental Indenture may be executed in any number of
counterparts, each of which so executed shall be deemed to be an original, but all such counterparts shall together constitute but one and the same instrument. 
  

	 	Section 3.04	Recitals. 

 The recitals contained herein shall be taken as statements of the Company,
and the Trustee assumes no responsibility for their correctness. The Trustee makes no representations as to the validity or sufficiency of this Supplemental Indenture. 

[signature page follows] 

  
 3 

 IN WITNESS WHEREOF, the parties hereto have caused this Supplemental Indenture to be duly
executed by their respective officers hereunto duly authorized, all as of the day and year first written above. 
  

			
	NOBLE ENERGY, INC.
		
	By:		  

			Name:
			Title:

  

			
	Attest:
		
	By:		  

			Name:
			Title:

  

			
	WELLS FARGO BANK, NATIONAL ASSOCIATION,
	as Trustee
		
	By:		  

			Authorized Representative

 [Signature Page to Sixth Supplemental Indenture] 

 Exhibit A to 

Sixth Supplemental Indenture 

UNLESS THIS SECURITY IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (“DTC”), 55 WATER STREET, NEW
YORK, NEW YORK TO THE ISSUER OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND SUCH SECURITY ISSUED IS REGISTERED IN THE NAME OF CEDE & CO., OR SUCH OTHER NAME AS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC, ANY
TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL, SINCE THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 

TRANSFERS OF THIS SECURITY SHALL BE LIMITED TO TRANSFERS, IN WHOLE BUT NOT IN PART, TO NOMINEES OF DTC OR TO A SUCCESSOR THEREOF OR SUCH
SUCCESSOR’S NOMINEE EXCEPT AS OTHERWISE PROVIDED IN THE INDENTURE REFERRED TO ON THE REVERSE SIDE OF THIS CERTIFICATE. 
 NOBLE ENERGY,
INC. 
 5.625% Senior Note Due 2021 
  

			
	REGISTERED		PRINCIPAL AMOUNT
	No.             		$            
	CUSIP NO.		

 NOBLE ENERGY, INC., a Delaware corporation (herein referred to as the “Company” which term
includes any successor entity under the Indenture herein referred to), for value received, hereby promises to pay to CEDE & CO., or registered assigns, upon presentation, the principal sum of
$        on May 1, 2021 (the “Stated Maturity Date”) and to pay interest thereon from May 1, 2015 or from the most recent Interest Payment Date to which interest has been paid or
duly provided for, semi-annually in arrears on May 1 and November 1 of each year (each, an “Interest Payment Date”), commencing November 1, 2015, at the rate of 5.625% per annum, until the principal hereof is
paid or duly provided for. The interest so payable, and punctually paid or duly provided for, on any Interest Payment Date will, as provided in such Indenture, be paid to the Holder in whose name this Security (or one or more Predecessor Debt
Securities) is registered at the close of business on the Regular Record Date for such interest, which shall be the April 15 or October 15 (whether or not a Business Day), as the case may be, next preceding such Interest Payment Date at
the office or agency of the Company maintained for such purpose; provided that such interest may be paid, at the Company’s option, by mailing a check to such Holder at its registered address. Any such interest not so punctually paid or
duly provided for shall forthwith cease to be payable to the Holder on such Regular Record Date, and may be paid to the Holder in whose name this Security (or one or more Predecessor Debt Securities) is registered at the close of business on a
Special Record Date for the payment of such Defaulted Interest to be fixed by the Trustee, notice whereof shall be given to Holders of Securities not less than ten days prior to such Special Record Date, or may be paid at any time in any other
lawful manner not inconsistent with the requirements of any securities exchange on which the Securities may be listed, and upon such notice as may be required by such exchange, all as more fully provided in the Indenture. Interest will be computed
on the basis of a 360-day year consisting of twelve 30-day months. The Company will pay, to the extent lawful, interest (including post-petition interest in any proceeding under any applicable federal or state bankruptcy, insolvency, reorganization
or other similar law) on overdue principal and interest at the rate per annum borne by this Security. 

  
 Exhibit A - 1 

 Payment of the principal of and interest on this Security will be made at the Corporate Trust
Office of the Trustee in the City of Dallas, Texas or the office of the Trustee in The City of New York, New York, in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private
debts. The Company, however, may pay principal and interest by check payable in such money. At the option of the Company, payment of interest may be made by check mailed to the address of the Person entitled thereto as such address shall appear in
the Debt Security Register; provided that, notwithstanding anything else contained herein, if this Security is a Global Security and is held in book-entry form through the facilities of the Depositary, payments on this Security will be made
to the Depositary or its nominee in accordance with the arrangements then in effect between the Trustee and the Depositary. 
 In any case
where any Interest Payment Date or Redemption Date or the Stated Maturity Date of this Security shall not be a Business Day, then the related payment of interest or principal and premium, if any, need not be made on such date, but may be made on the
next succeeding Business Day with the same force and effect as if made on such Interest Payment Date or Redemption Date or on the Stated Maturity Date, and, if such payment is made or duly provided for on such Business Day, no interest shall accrue
on the amount so payable for the period from and after such Interest Payment Date, Redemption Date or the Stated Maturity Date, as the case may be, to such Business Day. For purposes of this Security, the term “Business Day” means
any day, other than a Saturday or Sunday, that is not a day on which banking institutions or trust companies are generally authorized or required by law, regulation or executive order to close in The City of New York. 

Reference is hereby made to the further provisions of this Security set forth on the reverse hereof, which further provisions shall for all
purposes have the same effect as if set forth at this place. 
 Unless the Certificate of Authentication hereon has been executed by the
Trustee by manual signature of one of its authorized signatories, this Security shall not be entitled to any benefit under the Indenture, or be valid or obligatory for any purpose. 

  
 Exhibit A - 2 

 IN WITNESS WHEREOF, the Company has caused this instrument to be executed by one of its duly
authorized officers. 
  

													
	Dated:		  
								
					
									NOBLE ENERGY, INC.
						
									By:		  

											Name:		
											Title:		
					
	Attest:								
						
	By:		  
								
			Name:										
			Title:										

 TRUSTEE’S CERTIFICATE OF AUTHENTICATION: 

This is one of the Debt Securities of the series designated therein referred to in the within-mentioned Indenture. 

 

									
	Dated:		  
						
				
							WELLS FARGO BANK, NATIONAL ASSOCIATION,
							as Trustee
					
							By:		  

									Authorized Representative

  
 Exhibit A - 3 

 [Reverse of Note] 

NOBLE ENERGY, INC. 
 This
Security is one of a duly authorized issue of Debt Securities of the Company designated as its “5.625% Senior Notes due 2021” (herein called the “Securities”), initially limited in aggregate principal amount of
$700,000,000 issued under an Indenture dated as of February 27, 2009, as amended and supplemented by the First Supplemental Indenture thereto dated as of February 27, 2009, the Second Supplemental Indenture thereto dated as of
February 18, 2011, the Third Supplemental Indenture thereto dated as of December 8, 2011, the Fourth Supplemental Indenture thereto dated as of November 8, 2013, the Fifth Supplemental Indenture thereto dated as of November 7,
2014 and the Sixth Supplemental Indenture thereto dated as of [            ], 2015 (as so amended and supplemented, and as hereafter amended and supplemented from time to time, the
“Indenture”), between the Company and Wells Fargo Bank, National Association, as trustee (herein called the “Trustee,” which term includes any successor trustee under the Indenture with respect to the series of
which this Debt Security is a part), to which Indenture and all indentures supplemental thereto reference is hereby made for a statement of the respective rights, limitations of rights, duties and immunities thereunder of the Company, the Trustee
and the Holders of the Securities, and of the terms upon which the Securities are, and are to be, authenticated and delivered. To the extent that any provision of this Security conflicts with the express provisions of the Indenture, the provisions
of this Security will govern and be controlling (to the extent permitted by law). All terms used in this Security which are defined in the Indenture shall have the meanings assigned to them in the Indenture. 

Except as otherwise described herein, the Company will not be entitled to redeem the Securities at its option prior to May 1, 2017. The
Securities will be redeemable, at the Company’s option, in whole at any time or in part from time to time, on and after May 1, 2017, upon not less than 30 nor more than 60 days’ notice, at the following Redemption Prices (expressed as
percentages of the principal amount thereof) if redeemed during the twelve-month period commencing on May 1 of the years set forth below, plus, in each case, unpaid accrued interest, if any, thereon to the Redemption Date: 

 

					
	 Year
	  	Percentage	 
	 2017
	  	 	102.813	% 
	 2018
	  	 	101.406	% 
	 2019 and thereafter
	  	 	100.000	% 

 In addition, the Securities may be redeemed, in whole or in part, at any time prior to May 1, 2017 at the
option of the Company upon not less than 30 nor more than 60 days’ prior notice sent to each Holder at its registered address, at a Redemption Price equal to 100% of the principal amount of the Securities redeemed plus the Applicable Premium as
of, and accrued and unpaid interest to, the applicable Redemption Date (subject to the right of holders of record on the relevant record date to receive interest due on the relevant Interest Payment Date). 

“Applicable Premium” means, with respect to any Security on any applicable Redemption Date, the greater of: 

 

	 	(1)	1.0% of the principal amount of such Security; or 

  

	 	(2)	the excess, if any, of: 

 (a) the present value at such Redemption Date of
(i) the Redemption Price of such Security at May 1, 2017 (such Redemption Price being set forth in the table 

  
 Exhibit A - 4 

 
appearing above) plus (ii) all required interest payments (excluding accrued and unpaid interest to such Redemption Date) due on such Security through May 1, 2017 computed using a
discount rate equal to the Treasury Rate as of such Redemption Date plus 50 basis points; over 
 (b) the principal amount of
such Security. 
 “Treasury Rate” means, as of any Redemption Date, the yield to maturity at the time of computation of
United States Treasury securities with a constant maturity (as compiled and published in the most recent Federal Reserve Statistical Release H.15 (519) which has become publicly available at least two Business Days prior to the Redemption Date
(or, if such Statistical Release is no longer published, any publicly available source of similar market data)) most nearly equal to the period from the Redemption Date to May 1, 2017; provided, however, that if the period from
the Redemption Date to May 1, 2017 is not equal to the constant maturity of a United States Treasury security for which a weekly average yield is given, the Treasury Rate shall be obtained by linear interpolation (calculated to the nearest
one-twelfth of a year) from the weekly average yields of United States Treasury securities for which such yields are given, except that if the period from the Redemption Date to May 1, 2017 is less than one year, the weekly average yield on
actually traded United States Treasury securities adjusted to a constant maturity of one year shall be used. The Company will (a) calculate the Treasury Rate as of the second Business Day preceding the applicable Redemption Date and
(b) prior to such Redemption Date file with the Trustee an Officers’ Certificate setting forth the Applicable Premium and the Treasury Rate and showing the calculation of each in reasonable detail. 

“Redemption Price” when used with respect to any Security to be redeemed, means the price fixed for such redemption,
including principal and premium, if any, pursuant to the Indenture and the Security. 
 Notice of redemption will be sent to Holders of
Securities, at least 30 but not more than 60 days prior to the Redemption Date, all as provided in the Indenture. 
 In the event of
redemption of this Security in part only, a new Security or Securities for the unredeemed portion hereof shall be issued in the name of the Holder hereof upon the cancellation hereof. 

If an Event of Default with respect to the Securities shall occur and be continuing, the principal of the Securities may be declared due and
payable in the manner and with the effect provided in the Indenture. 
 The Indenture permits, with certain exceptions as provided therein,
the amendment thereof and the modification of the rights and obligations of the Company and the rights of the Holders of the Debt Securities of any series under the Indenture at any time by the Company and the Trustee with the consent of the Holders
of not less than a majority of the aggregate principal amount of the Outstanding Debt Securities of such series. The Indenture also contains provisions permitting the Holders of not less than a majority of the aggregate principal amount of the
Outstanding Debt Securities of any series, on behalf of the Holders of all such securities of that series, to waive compliance by the Company with certain provisions of the Indenture and to waive certain past defaults under the Indenture with
respect to such series and their consequences. Any such consent or waiver by the Holder of this Security shall be conclusive and binding upon such Holder and upon all future Holders of this Security and other Securities issued upon the registration
of transfer hereof or in exchange hereof or in lieu hereof, whether or not notation of such consent or waiver is made upon this Security. 

  
 Exhibit A - 5 

 No sinking fund will be established with respect to the Securities and the Securities shall not
be subject to any sinking fund payments. Articles VI and XIII of the Indenture shall be applicable in their entirety to the Securities. 

The Indenture contains provisions for defeasance of (i) the entire indebtedness of the Company in respect of this Security and
(ii) certain restrictive covenants and the related Events of Default, subject to compliance by the Company with certain conditions set forth in the Indenture. 

No reference herein to the Indenture and no provision of this Security or of the Indenture shall alter or impair the obligation of the
Company, which is absolute and unconditional, to pay the principal of, premium, if any, and interest on this Security at the times, places and rate, and in the coin or currency, herein prescribed. 

As provided in the Indenture and subject to certain limitations therein and herein set forth, the transfer of this Security is registrable in
the Debt Security Register of the Company upon surrender of this Security for registration of transfer at the office or agency of the Company in any place where the principal of and interest on this Security are payable, duly endorsed by, or
accompanied by a written instrument of transfer in form satisfactory to the Company and the Debt Security Registrar duly executed by, the Holder hereof or by his attorney duly authorized in writing, and thereupon one or more new Securities, of
authorized denominations and for the same aggregate principal amount, will be issued to the designated transferee or transferees. 
 As
provided in the Indenture and subject to certain limitations therein and herein set forth, this Security is exchangeable for a like aggregate principal amount of Securities of different authorized denominations but otherwise having the same terms
and conditions, as requested by the Holder hereof surrendering the same. 
 The Securities are issuable only in registered form without
coupons in denominations of $1,000 and integral multiples of $1,000 in excess thereof. 
 No service charge shall be made for any such
registration of transfer or exchange, but the Company may require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 

The registered Holder of this Security may be treated as its owner for all purposes. 

Prior to due presentment of this Security for registration of transfer, the Company, the Trustee and any agent of the Company or the Trustee
may treat the Person in whose name this Security is registered as the owner hereof for all purposes, whether or not this Security be overdue, and none of the Company, the Trustee and any such agent shall be affected by notice to the contrary. 

No recourse shall be had for the payment of the principal of or premium, if any, or the interest on this Security, or for any claim based
hereon, or otherwise in respect hereof, or based on or in respect of the Indenture or any indenture supplemental thereto, against any past, present or future stockholder, employee, officer or director, as such, of the Company or of any successor,
either directly or through the Company or any successor, whether by virtue of any constitution, statute or rule of law or by the enforcement of any assessment or penalty or otherwise, all such liability being, by the acceptance hereof and as part of
the consideration for the issue hereof, expressly waived and released. 
 The Securities shall be governed by and construed in accordance
with the laws of the State of New York. 

  
 Exhibit A - 6 

 Pursuant to a recommendation promulgated by the Committee on Uniform Security Identification
Procedures, the Company has caused “CUSIP” numbers to be printed on the Securities as a convenience to the Holders of such Securities. No representation is made as to the correctness or accuracy of such CUSIP numbers as printed on the
Securities, and reliance may be placed only on the other identification numbers printed hereon. 

  
 Exhibit A - 7 

 ASSIGNMENT FORM 

FOR VALUE RECEIVED, the undersigned hereby sells, assigns and transfers unto 
  

			
	  
		
	(Please Print or Type Name and Address Including Zip Code of Assignee)		

 the within Debt Security of Noble Energy, Inc. and hereby does irrevocably constitute and appoint
                    Attorney to transfer said security on the books of the within-named Corporation with full power of substitution in the premises.

  

			
	  
		
	(Please Insert Social Security or Other Identifying Number of Assignee)		

  

			
	Dated:		  

 SIGNATURE GUARANTEE 

Signatures must be guaranteed by an “eligible guarantor institution” meeting the requirements of Wells Fargo Bank, National
Association, which requirements include membership or participation in the Security Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be determined by Wells Fargo Bank, National
Association in addition to, or in substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934 as amended. 
 NOTICE:
The signature to this assignment must correspond with the name as it appears on the first page of the within Security in every particular, without alteration or enlargement of any change whatever. 

 

	
	  

	Signature Guarantee

  
 Exhibit A - 8 

 Exhibit B to 

Sixth Supplemental Indenture 

UNLESS THIS SECURITY IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (“DTC”), 55 WATER STREET, NEW
YORK, NEW YORK TO THE ISSUER OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND SUCH SECURITY ISSUED IS REGISTERED IN THE NAME OF CEDE & CO., OR SUCH OTHER NAME AS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC, ANY
TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL, SINCE THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 

TRANSFERS OF THIS SECURITY SHALL BE LIMITED TO TRANSFERS, IN WHOLE BUT NOT IN PART, TO NOMINEES OF DTC OR TO A SUCCESSOR THEREOF OR SUCH
SUCCESSOR’S NOMINEE EXCEPT AS OTHERWISE PROVIDED IN THE INDENTURE REFERRED TO ON THE REVERSE SIDE OF THIS CERTIFICATE. 
 NOBLE ENERGY,
INC. 
 5.875% Senior Note Due 2022 
  

			
	REGISTERED		PRINCIPAL AMOUNT
	No.             		$        
	CUSIP NO.		

 NOBLE ENERGY, INC., a Delaware corporation (herein referred to as the “Company” which term
includes any successor entity under the Indenture herein referred to), for value received, hereby promises to pay to CEDE & CO., or registered assigns, upon presentation, the principal sum of $
        on June 1, 2022 (the “Stated Maturity Date”) and to pay interest thereon from June 1, 2015 or from the most recent Interest Payment Date to which interest has been paid or
duly provided for, semi-annually in arrears on June 1 and December 1 of each year (each, an “Interest Payment Date”), commencing December 1, 2015, at the rate of 5.875% per annum, until the principal hereof is
paid or duly provided for. The interest so payable, and punctually paid or duly provided for, on any Interest Payment Date will, as provided in such Indenture, be paid to the Holder in whose name this Security (or one or more Predecessor Debt
Securities) is registered at the close of business on the Regular Record Date for such interest, which shall be the May 15 or November 15 (whether or not a Business Day), as the case may be, next preceding such Interest Payment Date at the
office or agency of the Company maintained for such purpose; provided that such interest may be paid, at the Company’s option, by mailing a check to such Holder at its registered address. Any such interest not so punctually paid or duly
provided for shall forthwith cease to be payable to the Holder on such Regular Record Date, and may be paid to the Holder in whose name this Security (or one or more Predecessor Debt Securities) is registered at the close of business on a Special
Record Date for the payment of such Defaulted Interest to be fixed by the Trustee, notice whereof shall be given to Holders of Securities not less than ten days prior to such Special Record Date, or may be paid at any time in any other lawful manner
not inconsistent with the requirements of any securities exchange on which the Securities may be listed, and upon such notice as may be required by such exchange, all as more fully provided in the Indenture. Interest will be computed on the basis of
a 360-day year consisting of twelve 30-day months. The Company will pay, to the extent lawful, interest (including post-petition interest in any proceeding under any applicable federal or state bankruptcy, insolvency, reorganization or other similar
law) on overdue principal and interest at the rate per annum borne by this Security. 

  
 Exhibit B - 1 

 Payment of the principal of and interest on this Security will be made at the Corporate Trust
Office of the Trustee in the City of Dallas, Texas or the office of the Trustee in The City of New York, New York, in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private
debts. The Company, however, may pay principal and interest by check payable in such money. At the option of the Company, payment of interest may be made by check mailed to the address of the Person entitled thereto as such address shall appear in
the Debt Security Register; provided that, notwithstanding anything else contained herein, if this Security is a Global Security and is held in book-entry form through the facilities of the Depositary, payments on this Security will be made
to the Depositary or its nominee in accordance with the arrangements then in effect between the Trustee and the Depositary. 
 In any case
where any Interest Payment Date or Redemption Date or the Stated Maturity Date of this Security shall not be a Business Day, then the related payment of interest or principal and premium, if any, need not be made on such date, but may be made on the
next succeeding Business Day with the same force and effect as if made on such Interest Payment Date or Redemption Date or on the Stated Maturity Date, and, if such payment is made or duly provided for on such Business Day, no interest shall accrue
on the amount so payable for the period from and after such Interest Payment Date, Redemption Date or the Stated Maturity Date, as the case may be, to such Business Day. For purposes of this Security, the term “Business Day” means
any day, other than a Saturday or Sunday, that is not a day on which banking institutions or trust companies are generally authorized or required by law, regulation or executive order to close in The City of New York. 

Reference is hereby made to the further provisions of this Security set forth on the reverse hereof, which further provisions shall for all
purposes have the same effect as if set forth at this place. 
 Unless the Certificate of Authentication hereon has been executed by the
Trustee by manual signature of one of its authorized signatories, this Security shall not be entitled to any benefit under the Indenture, or be valid or obligatory for any purpose. 

  
 Exhibit B - 2 

 IN WITNESS WHEREOF, the Company has caused this instrument to be executed by one of its duly
authorized officers. 
  

													
	Dated:		  
								
					
									NOBLE ENERGY, INC.
						
									By:		  

											Name:		
											Title:		
					
	Attest:								
						
	By:		  
								
			Name:										
			Title:										

 TRUSTEE’S CERTIFICATE OF AUTHENTICATION: 

This is one of the Debt Securities of the series designated therein referred to in the within-mentioned Indenture. 

 

									
	Dated:		  
						
				
							WELLS FARGO BANK, NATIONAL ASSOCIATION,
							as Trustee
					
							By:		  

									Authorized Representative

  
 Exhibit B - 3 

 [Reverse of Note] 

NOBLE ENERGY, INC. 
 This
Security is one of a duly authorized issue of Debt Securities of the Company designated as its “5.875% Senior Notes due 2022” (herein called the “Securities”), initially limited in aggregate principal amount of
$600,000,000 issued under an Indenture dated as of February 27, 2009, as amended and supplemented by the First Supplemental Indenture thereto dated as of February 27, 2009, the Second Supplemental Indenture thereto dated as of
February 18, 2011, the Third Supplemental Indenture thereto dated as of December 8, 2011, the Fourth Supplemental Indenture thereto dated as of November 8, 2013, the Fifth Supplemental Indenture thereto dated as of November 7,
2014 and the Sixth Supplemental Indenture thereto dated as of [            ], 2015 (as so amended and supplemented, and as hereafter amended and supplemented from time to time, the
“Indenture”), between the Company and Wells Fargo Bank, National Association, as trustee (herein called the “Trustee,” which term includes any successor trustee under the Indenture with respect to the series of
which this Debt Security is a part), to which Indenture and all indentures supplemental thereto reference is hereby made for a statement of the respective rights, limitations of rights, duties and immunities thereunder of the Company, the Trustee
and the Holders of the Securities, and of the terms upon which the Securities are, and are to be, authenticated and delivered. To the extent that any provision of this Security conflicts with the express provisions of the Indenture, the provisions
of this Security will govern and be controlling (to the extent permitted by law). All terms used in this Security which are defined in the Indenture shall have the meanings assigned to them in the Indenture. 

Except as otherwise described herein, the Company will not be entitled to redeem the Securities at its option prior to December 1, 2017.
The Securities will be redeemable, at the Company’s option, in whole at any time or in part from time to time, on and after December 1, 2017, upon not less than 30 nor more than 60 days’ notice, at the following Redemption Prices
(expressed as percentages of the principal amount thereof) if redeemed during the twelve-month period commencing on December 1 of the years set forth below, plus, in each case, unpaid accrued interest, if any, thereon to the Redemption Date:

  

					
	 Year
	  	Percentage	 
	 2017
	  	 	102.938	% 
	 2018
	  	 	101.469	% 
	 2019 and thereafter
	  	 	100.000	% 

 In addition, the Securities may be redeemed, in whole or in part, at any time prior to December 1, 2017
at the option of the Company upon not less than 30 nor more than 60 days’ prior notice sent to each Holder at its registered address, at a Redemption Price equal to 100% of the principal amount of the Securities redeemed plus the Applicable
Premium as of, and accrued and unpaid interest to, the applicable Redemption Date (subject to the right of holders of record on the relevant record date to receive interest due on the relevant Interest Payment Date. 

“Applicable Premium” means, with respect to any Security on any applicable Redemption Date, the greater of: 

 

	 	(1)	1.0% of the principal amount of such Security; or 

  

	 	(2)	the excess, if any, of: 

 (a) the present value at such Redemption Date of
(i) the Redemption Price of such Security at December 1, 2017 (such Redemption Price being set forth in the table 

  
 Exhibit B - 4 

 
appearing above) plus (ii) all required interest payments (excluding accrued and unpaid interest to such Redemption Date) due on such Security through December 1, 2017 computed using a
discount rate equal to the Treasury Rate as of such Redemption Date plus 50 basis points; over 
 (b) the principal amount of
such Security. 
 “Treasury Rate” means, as of any Redemption Date, the yield to maturity at the time of computation of
United States Treasury securities with a constant maturity (as compiled and published in the most recent Federal Reserve Statistical Release H.15 (519) which has become publicly available at least two Business Days prior to the Redemption Date
(or, if such Statistical Release is no longer published, any publicly available source of similar market data)) most nearly equal to the period from the Redemption Date to December 1, 2017; provided, however, that if the period
from the Redemption Date to December 1, 2017 is not equal to the constant maturity of a United States Treasury security for which a weekly average yield is given, the Treasury Rate shall be obtained by linear interpolation (calculated to the
nearest one-twelfth of a year) from the weekly average yields of United States Treasury securities for which such yields are given, except that if the period from the Redemption Date to December 1, 2017 is less than one year, the weekly average
yield on actually traded United States Treasury securities adjusted to a constant maturity of one year shall be used. The Company will (a) calculate the Treasury Rate as of the second Business Day preceding the applicable Redemption Date and
(b) prior to such Redemption Date file with the Trustee an Officers’ Certificate setting forth the Applicable Premium and the Treasury Rate and showing the calculation of each in reasonable detail. 

“Redemption Price” when used with respect to any Security to be redeemed, means the price fixed for such redemption,
including principal and premium, if any, pursuant to the Indenture and the Security. 
 Notice of redemption will be sent to Holders of
Securities, at least 30 but not more than 60 days prior to the Redemption Date, all as provided in the Indenture. 
 In the event of
redemption of this Security in part only, a new Security or Securities for the unredeemed portion hereof shall be issued in the name of the Holder hereof upon the cancellation hereof. 

If an Event of Default with respect to the Securities shall occur and be continuing, the principal of the Securities may be declared due and
payable in the manner and with the effect provided in the Indenture. 
 The Indenture permits, with certain exceptions as provided therein,
the amendment thereof and the modification of the rights and obligations of the Company and the rights of the Holders of the Debt Securities of any series under the Indenture at any time by the Company and the Trustee with the consent of the Holders
of not less than a majority of the aggregate principal amount of the Outstanding Debt Securities of such series. The Indenture also contains provisions permitting the Holders of not less than a majority of the aggregate principal amount of the
Outstanding Debt Securities of any series, on behalf of the Holders of all such securities of that series, to waive compliance by the Company with certain provisions of the Indenture and to waive certain past defaults under the Indenture with
respect to such series and their consequences. Any such consent or waiver by the Holder of this Security shall be conclusive and binding upon such Holder and upon all future Holders of this Security and other Securities issued upon the registration
of transfer hereof or in exchange hereof or in lieu hereof, whether or not notation of such consent or waiver is made upon this Security. 

  
 Exhibit B - 5 

 No sinking fund will be established with respect to the Securities and the Securities shall not
be subject to any sinking fund payments. Articles VI and XIII of the Indenture shall be applicable in their entirety to the Securities. 

The Indenture contains provisions for defeasance of (i) the entire indebtedness of the Company in respect of this Security and
(ii) certain restrictive covenants and the related Events of Default, subject to compliance by the Company with certain conditions set forth in the Indenture. 

No reference herein to the Indenture and no provision of this Security or of the Indenture shall alter or impair the obligation of the
Company, which is absolute and unconditional, to pay the principal of, premium, if any, and interest on this Security at the times, places and rate, and in the coin or currency, herein prescribed. 

As provided in the Indenture and subject to certain limitations therein and herein set forth, the transfer of this Security is registrable in
the Debt Security Register of the Company upon surrender of this Security for registration of transfer at the office or agency of the Company in any place where the principal of and interest on this Security are payable, duly endorsed by, or
accompanied by a written instrument of transfer in form satisfactory to the Company and the Debt Security Registrar duly executed by, the Holder hereof or by his attorney duly authorized in writing, and thereupon one or more new Securities, of
authorized denominations and for the same aggregate principal amount, will be issued to the designated transferee or transferees. 
 As
provided in the Indenture and subject to certain limitations therein and herein set forth, this Security is exchangeable for a like aggregate principal amount of Securities of different authorized denominations but otherwise having the same terms
and conditions, as requested by the Holder hereof surrendering the same. 
 The Securities are issuable only in registered form without
coupons in denominations of $1,000 and integral multiples of $1,000 in excess thereof. 
 No service charge shall be made for any such
registration of transfer or exchange, but the Company may require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 

The registered Holder of this Security may be treated as its owner for all purposes. 

Prior to due presentment of this Security for registration of transfer, the Company, the Trustee and any agent of the Company or the Trustee
may treat the Person in whose name this Security is registered as the owner hereof for all purposes, whether or not this Security be overdue, and none of the Company, the Trustee and any such agent shall be affected by notice to the contrary. 

No recourse shall be had for the payment of the principal of or premium, if any, or the interest on this Security, or for any claim based
hereon, or otherwise in respect hereof, or based on or in respect of the Indenture or any indenture supplemental thereto, against any past, present or future stockholder, employee, officer or director, as such, of the Company or of any successor,
either directly or through the Company or any successor, whether by virtue of any constitution, statute or rule of law or by the enforcement of any assessment or penalty or otherwise, all such liability being, by the acceptance hereof and as part of
the consideration for the issue hereof, expressly waived and released. 
 The Securities shall be governed by and construed in accordance
with the laws of the State of New York. 

  
 Exhibit B - 6 

 Pursuant to a recommendation promulgated by the Committee on Uniform Security Identification
Procedures, the Company has caused “CUSIP” numbers to be printed on the Securities as a convenience to the Holders of such Securities. No representation is made as to the correctness or accuracy of such CUSIP numbers as printed on the
Securities, and reliance may be placed only on the other identification numbers printed hereon. 

  
 Exhibit B - 7 

 ASSIGNMENT FORM 

FOR VALUE RECEIVED, the undersigned hereby sells, assigns and transfers unto 
  

			
	  
		
	(Please Print or Type Name and Address Including Zip Code of Assignee)		

 the within Debt Security of Noble Energy, Inc. and hereby does irrevocably constitute and appoint
                     Attorney to transfer said security on the books of the within-named Corporation with full power of substitution in the premises.

  

			
	  
		
	(Please Insert Social Security or Other Identifying Number of Assignee)		

  

			
	Dated:		  

 SIGNATURE GUARANTEE 

Signatures must be guaranteed by an “eligible guarantor institution” meeting the requirements of Wells Fargo Bank, National
Association, which requirements include membership or participation in the Security Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be determined by Wells Fargo Bank, National
Association in addition to, or in substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934 as amended. 
 NOTICE:
The signature to this assignment must correspond with the name as it appears on the first page of the within Security in every particular, without alteration or enlargement of any change whatever. 

 

	
	  

	Signature Guarantee

  
 Exhibit B - 8 

 Exhibit C to 

Sixth Supplemental Indenture 

UNLESS THIS SECURITY IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (“DTC”), 55 WATER STREET, NEW
YORK, NEW YORK TO THE ISSUER OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND SUCH SECURITY ISSUED IS REGISTERED IN THE NAME OF CEDE & CO., OR SUCH OTHER NAME AS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC, ANY
TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL, SINCE THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 

TRANSFERS OF THIS SECURITY SHALL BE LIMITED TO TRANSFERS, IN WHOLE BUT NOT IN PART, TO NOMINEES OF DTC OR TO A SUCCESSOR THEREOF OR SUCH
SUCCESSOR’S NOMINEE EXCEPT AS OTHERWISE PROVIDED IN THE INDENTURE REFERRED TO ON THE REVERSE SIDE OF THIS CERTIFICATE. 
 NOBLE ENERGY,
INC. 
 5.875% Senior Note Due 2024 
  

			
	REGISTERED		PRINCIPAL AMOUNT
	No.             		$        
	CUSIP NO.		

 NOBLE ENERGY, INC., a Delaware corporation (herein referred to as the “Company” which term
includes any successor entity under the Indenture herein referred to), for value received, hereby promises to pay to CEDE & CO., or registered assigns, upon presentation, the principal sum of
$         on June 1, 2024 (the “Stated Maturity Date”) and to pay interest thereon from June 1, 2015 or from the most recent Interest Payment Date to which interest has been paid or
duly provided for, semi-annually in arrears on June 1 and December 1 of each year (each, an “Interest Payment Date”), commencing December 1, 2015, at the rate of 5.875% per annum, until the principal hereof is
paid or duly provided for. The interest so payable, and punctually paid or duly provided for, on any Interest Payment Date will, as provided in such Indenture, be paid to the Holder in whose name this Security (or one or more Predecessor Debt
Securities) is registered at the close of business on the Regular Record Date for such interest, which shall be the May 15 or November 15 (whether or not a Business Day), as the case may be, next preceding such Interest Payment Date at the
office or agency of the Company maintained for such purpose; provided that such interest may be paid, at the Company’s option, by mailing a check to such Holder at its registered address. Any such interest not so punctually paid or duly
provided for shall forthwith cease to be payable to the Holder on such Regular Record Date, and may be paid to the Holder in whose name this Security (or one or more Predecessor Debt Securities) is registered at the close of business on a Special
Record Date for the payment of such Defaulted Interest to be fixed by the Trustee, notice whereof shall be given to Holders of Securities not less than ten days prior to such Special Record Date, or may be paid at any time in any other lawful manner
not inconsistent with the requirements of any securities exchange on which the Securities may be listed, and upon such notice as may be required by such exchange, all as more fully provided in the Indenture. Interest will be computed on the basis of
a 360-day year consisting of twelve 30-day months. The Company will pay, to the extent lawful, interest (including post-petition interest in any proceeding under any applicable federal or state bankruptcy, insolvency, reorganization or other similar
law) on overdue principal and interest at the rate per annum borne by this Security. 

  
 Exhibit C - 1 

 Payment of the principal of and interest on this Security will be made at the Corporate Trust
Office of the Trustee in the City of Dallas, Texas or the office of the Trustee in The City of New York, New York, in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private
debts. The Company, however, may pay principal and interest by check payable in such money. At the option of the Company, payment of interest may be made by check mailed to the address of the Person entitled thereto as such address shall appear in
the Debt Security Register; provided that, notwithstanding anything else contained herein, if this Security is a Global Security and is held in book-entry form through the facilities of the Depositary, payments on this Security will be made
to the Depositary or its nominee in accordance with the arrangements then in effect between the Trustee and the Depositary. 
 In any case
where any Interest Payment Date or Redemption Date or the Stated Maturity Date of this Security shall not be a Business Day, then the related payment of interest or principal and premium, if any, need not be made on such date, but may be made on the
next succeeding Business Day with the same force and effect as if made on such Interest Payment Date or Redemption Date or on the Stated Maturity Date, and, if such payment is made or duly provided for on such Business Day, no interest shall accrue
on the amount so payable for the period from and after such Interest Payment Date, Redemption Date or the Stated Maturity Date, as the case may be, to such Business Day. For purposes of this Security, the term “Business Day” means
any day, other than a Saturday or Sunday, that is not a day on which banking institutions or trust companies are generally authorized or required by law, regulation or executive order to close in The City of New York. 

Reference is hereby made to the further provisions of this Security set forth on the reverse hereof, which further provisions shall for all
purposes have the same effect as if set forth at this place. 
 Unless the Certificate of Authentication hereon has been executed by the
Trustee by manual signature of one of its authorized signatories, this Security shall not be entitled to any benefit under the Indenture, or be valid or obligatory for any purpose. 

  
 Exhibit C - 2 

 IN WITNESS WHEREOF, the Company has caused this instrument to be executed by one of its duly
authorized officers. 
  

													
	Dated:		  
								
					
									NOBLE ENERGY, INC.
						
									By:		  

											Name:		
											Title:		
					
	Attest:								
						
	By:		  
								
			Name:										
			Title:										

 TRUSTEE’S CERTIFICATE OF AUTHENTICATION: 

This is one of the Debt Securities of the series designated therein referred to in the within-mentioned Indenture. 

 

									
	Dated:		  
						
				
							WELLS FARGO BANK, NATIONAL ASSOCIATION,
							as Trustee
					
							By:		  

									Authorized Representative

  
 Exhibit C - 3 

 [Reverse of Note] 

NOBLE ENERGY, INC. 
 This
Security is one of a duly authorized issue of Debt Securities of the Company designated as its “5.875% Senior Notes due 2024” (herein called the “Securities”), initially limited in aggregate principal amount of
$500,000,000 issued under an Indenture dated as of February 27, 2009, as amended and supplemented by the First Supplemental Indenture thereto dated as of February 27, 2009, the Second Supplemental Indenture thereto dated as of
February 18, 2011, the Third Supplemental Indenture thereto dated as of December 8, 2011, the Fourth Supplemental Indenture thereto dated as of November 8, 2013, the Fifth Supplemental Indenture thereto dated as of November 7,
2014 and the Sixth Supplemental Indenture thereto dated as of [            ], 2015 (as so amended and supplemented, and as hereafter amended and supplemented from time to time, the
“Indenture”), between the Company and Wells Fargo Bank, National Association, as trustee (herein called the “Trustee,” which term includes any successor trustee under the Indenture with respect to the series of
which this Debt Security is a part), to which Indenture and all indentures supplemental thereto reference is hereby made for a statement of the respective rights, limitations of rights, duties and immunities thereunder of the Company, the Trustee
and the Holders of the Securities, and of the terms upon which the Securities are, and are to be, authenticated and delivered. To the extent that any provision of this Security conflicts with the express provisions of the Indenture, the provisions
of this Security will govern and be controlling (to the extent permitted by law). All terms used in this Security which are defined in the Indenture shall have the meanings assigned to them in the Indenture. 

Except as otherwise described herein, the Company will not be entitled to redeem the Securities at its option prior to June 1, 2019. The
Securities will be redeemable, at the Company’s option, in whole at any time or in part from time to time, on and after June 1, 2019, upon not less than 30 nor more than 60 days’ notice, at the following Redemption Prices (expressed
as percentages of the principal amount thereof) if redeemed during the twelve-month period commencing on June 1 of the years set forth below, plus, in each case, unpaid accrued interest, if any, thereon to the Redemption Date: 

 

					
	 Year
	  	Percentage	 
	 2019
	  	 	102.938	% 
	 2020
	  	 	101.958	% 
	 2021
	  	 	100.979	% 
	 2022 and thereafter
	  	 	100.000	% 

 In addition, the Securities may be redeemed, in whole or in part, at any time prior to June 1, 2019 at
the option of the Company upon not less than 30 nor more than 60 days’ prior notice sent to each Holder at its registered address, at a Redemption Price equal to 100% of the principal amount of the Securities redeemed plus the Applicable
Premium as of, and accrued and unpaid interest to, the applicable Redemption Date (subject to the right of holders of record on the relevant record date to receive interest due on the relevant Interest Payment Date). 

“Applicable Premium” means, with respect to any Security on any applicable Redemption Date, the greater of: 

 

	 	(1)	1.0% of the principal amount of such Security; or 

  

	 	(2)	the excess, if any, of: 

 (a) the present value at such Redemption Date of
(i) the Redemption Price of such Security at June 1, 2019 (such Redemption Price being set forth in the table appearing above) plus (ii) all required interest payments (excluding accrued and unpaid interest to such Redemption Date)
due on such Security through June 1, 2019 computed using a discount rate equal to the Treasury Rate as of such Redemption Date plus 50 basis points; over 

(b) the principal amount of such Security. 

  
 Exhibit C - 4 

 “Treasury Rate” means, as of any Redemption Date, the yield to maturity at the
time of computation of United States Treasury securities with a constant maturity (as compiled and published in the most recent Federal Reserve Statistical Release H.15 (519) which has become publicly available at least two Business Days prior
to the Redemption Date (or, if such Statistical Release is no longer published, any publicly available source of similar market data)) most nearly equal to the period from the Redemption Date to June 1, 2019; provided, however,
that if the period from the Redemption Date to June 1, 2019 is not equal to the constant maturity of a United States Treasury security for which a weekly average yield is given, the Treasury Rate shall be obtained by linear interpolation
(calculated to the nearest one-twelfth of a year) from the weekly average yields of United States Treasury securities for which such yields are given, except that if the period from the Redemption Date to June 1, 2019 is less than one year, the
weekly average yield on actually traded United States Treasury securities adjusted to a constant maturity of one year shall be used. The Company will (a) calculate the Treasury Rate as of the second Business Day preceding the applicable
Redemption Date and (b) prior to such Redemption Date file with the Trustee an Officers’ Certificate setting forth the Applicable Premium and the Treasury Rate and showing the calculation of each in reasonable detail. 

“Redemption Price” when used with respect to any Security to be redeemed, means the price fixed for such redemption,
including principal and premium, if any, pursuant to the Indenture and the Security. 
 Notice of redemption will be sent to Holders of
Securities, at least 30 but not more than 60 days prior to the Redemption Date, all as provided in the Indenture. 
 In the event of
redemption of this Security in part only, a new Security or Securities for the unredeemed portion hereof shall be issued in the name of the Holder hereof upon the cancellation hereof. 

If an Event of Default with respect to the Securities shall occur and be continuing, the principal of the Securities may be declared due and
payable in the manner and with the effect provided in the Indenture. 
 The Indenture permits, with certain exceptions as provided therein,
the amendment thereof and the modification of the rights and obligations of the Company and the rights of the Holders of the Debt Securities of any series under the Indenture at any time by the Company and the Trustee with the consent of the Holders
of not less than a majority of the aggregate principal amount of the Outstanding Debt Securities of such series. The Indenture also contains provisions permitting the Holders of not less than a majority of the aggregate principal amount of the
Outstanding Debt Securities of any series, on behalf of the Holders of all such securities of that series, to waive compliance by the Company with certain provisions of the Indenture and to waive certain past defaults under the Indenture with
respect to such series and their consequences. Any such consent or waiver by the Holder of this Security shall be conclusive and binding upon such Holder and upon all future Holders of this Security and other Securities issued upon the registration
of transfer hereof or in exchange hereof or in lieu hereof, whether or not notation of such consent or waiver is made upon this Security. 

  
 Exhibit C - 5 

 No sinking fund will be established with respect to the Securities and the Securities shall not
be subject to any sinking fund payments. Articles VI and XIII of the Indenture shall be applicable in their entirety to the Securities. 

The Indenture contains provisions for defeasance of (i) the entire indebtedness of the Company in respect of this Security and
(ii) certain restrictive covenants and the related Events of Default, subject to compliance by the Company with certain conditions set forth in the Indenture. 

No reference herein to the Indenture and no provision of this Security or of the Indenture shall alter or impair the obligation of the
Company, which is absolute and unconditional, to pay the principal of, premium, if any, and interest on this Security at the times, places and rate, and in the coin or currency, herein prescribed. 

As provided in the Indenture and subject to certain limitations therein and herein set forth, the transfer of this Security is registrable in
the Debt Security Register of the Company upon surrender of this Security for registration of transfer at the office or agency of the Company in any place where the principal of and interest on this Security are payable, duly endorsed by, or
accompanied by a written instrument of transfer in form satisfactory to the Company and the Debt Security Registrar duly executed by, the Holder hereof or by his attorney duly authorized in writing, and thereupon one or more new Securities, of
authorized denominations and for the same aggregate principal amount, will be issued to the designated transferee or transferees. 
 As
provided in the Indenture and subject to certain limitations therein and herein set forth, this Security is exchangeable for a like aggregate principal amount of Securities of different authorized denominations but otherwise having the same terms
and conditions, as requested by the Holder hereof surrendering the same. 
 The Securities are issuable only in registered form without
coupons in denominations of $1,000 and integral multiples of $1,000 in excess thereof. 
 No service charge shall be made for any such
registration of transfer or exchange, but the Company may require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 

The registered Holder of this Security may be treated as its owner for all purposes. 

Prior to due presentment of this Security for registration of transfer, the Company, the Trustee and any agent of the Company or the Trustee
may treat the Person in whose name this Security is registered as the owner hereof for all purposes, whether or not this Security be overdue, and none of the Company, the Trustee and any such agent shall be affected by notice to the contrary. 

No recourse shall be had for the payment of the principal of or premium, if any, or the interest on this Security, or for any claim based
hereon, or otherwise in respect hereof, or based on or in respect of the Indenture or any indenture supplemental thereto, against any past, present or future stockholder, employee, officer or director, as such, of the Company or of any successor,
either directly or through the Company or any successor, whether by virtue of any constitution, statute or rule of law or by the enforcement of any assessment or penalty or otherwise, all such liability being, by the acceptance hereof and as part of
the consideration for the issue hereof, expressly waived and released. 
 The Securities shall be governed by and construed in accordance
with the laws of the State of New York. 

  
 Exhibit C - 6 

 Pursuant to a recommendation promulgated by the Committee on Uniform Security Identification
Procedures, the Company has caused “CUSIP” numbers to be printed on the Securities as a convenience to the Holders of such Securities. No representation is made as to the correctness or accuracy of such CUSIP numbers as printed on the
Securities, and reliance may be placed only on the other identification numbers printed hereon. 

  
 Exhibit C - 7 

 ASSIGNMENT FORM 

FOR VALUE RECEIVED, the undersigned hereby sells, assigns and transfers unto 
  

			
	  
		
	(Please Print or Type Name and Address Including Zip Code of Assignee)		

 the within Debt Security of Noble Energy, Inc. and hereby does irrevocably constitute and appoint
                     Attorney to transfer said security on the books of the within-named Corporation with full power of substitution in the premises.

  

			
	  
		
	(Please Insert Social Security or Other Identifying Number of Assignee)		

  

			
	Dated:		  

 SIGNATURE GUARANTEE 

Signatures must be guaranteed by an “eligible guarantor institution” meeting the requirements of Wells Fargo Bank, National
Association, which requirements include membership or participation in the Security Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be determined by Wells Fargo Bank, National
Association in addition to, or in substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934 as amended. 
 NOTICE:
The signature to this assignment must correspond with the name as it appears on the first page of the within Security in every particular, without alteration or enlargement of any change whatever. 

 

	
	  

	Signature Guarantee

  
 Exhibit C - 8EX-10.1

 Exhibit 10.1 

FIRST AMENDMENT TO 
 LOAN AND
SECURITY AGREEMENT 
 THIS FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT (the “Amendment”) is made and dated as of
June 23, 2015, and is entered into by and between ZP Opco, Inc., (f/k/a Zosano Pharma, Inc.), a Delaware corporation (“Borrower”), HERCULES CAPITAL FUNDING TRUST 2014-1, a Delaware statutory trust (“Trust”) and
HERCULES TECHNOLOGY GROWTH CAPITAL, INC., a Maryland corporation (“HTGC”, along with the Trust, collectively, “Lender”). 

RECITALS 

A.    Borrower and HTGC previously entered into that certain Loan and Security Agreement dated as of June 3, 2014
(the “Agreement”); 
 B.    Trust succeeded to certain of HTGC’s rights under the Agreement and
the related Loan Documents (as defined in the Agreement); 
 C.    Borrower desires to increase the amount of the Term
Loan and modify certain terms as more particularly set forth herein; 
 D.    Borrower, Trust and HTGC are willing to
amend the Agreement as provided herein, and in connection herewith, Borrower’s parent corporation, Zosano Pharma Corporation (f/k/a ZP Holdings, Inc.), a Delaware corporation (“ZPC”) will be required to (i) consent to the
amendment and agree to sign a supplement to the Joinder Agreement currently in effect, (ii) provide HTGC with a warrant to purchase shares of ZPC’s common stock on the terms and conditions as provided in such warrant (the
“Warrant”); and (iii) clarify Section 2(b) of the warrant issued to HTGC as of June 3, 2014 as provided in the First Amendment to Warrant to be executed contemporaneously herewith; and 

E.    Borrower acknowledges that without the additional consent, supplement to the Joinder Agreement, the Warrant and the
First Amendment to Warrant, Trust and HTGC would not enter into the Amendment. 
 AGREEMENT 

NOW, THEREFORE, based on the promises contained herein and for other good and valuable consideration, the receipt and sufficiency of which are
hereby acknowledged, Borrower, Trust and HTGC agree as follows: 
 1.    Unless otherwise defined herein, all capitalized terms shall
have the meaning provided in the Agreement. The recitals set forth above are hereby incorporated by reference. 
 2.    As of
June 23, 2014, all references in the Loan Documents (and any amendments thereto) to Zosano Pharma, Inc. shall be deemed to be to ZP Opco, Inc., and all references to ZP Holdings, Inc. shall be deemed to be to Zosano Pharma Corporation. 

 3.    As of the Effective Date, the preamble to the Agreement is amended and restated as
follows: 
 THIS LOAN AND SECURITY AGREEMENT is made and dated as of June 3, 2014, and is entered into by and between Zosano Pharma,
Inc., a Delaware corporation (“Borrower”), and HERCULES TECHNOLOGY GROWTH CAPITAL, INC., a Maryland corporation (“HTGC”, for itself and as agent for any successor or assignee of its interests hereunder (“Lender”)). 

4.    As of the Effective Date, Recital A of the Agreement is amended and restated as follows: 

A.    Borrower has requested Lender to make available to Borrower a loan in an aggregate principal amount
of up to Fifteen Million Dollars ($15,000,000) (the “Term Loan”), with the maximum amount each Lender is required to loan as set forth in Schedule A; and 

5.    As of the Effective Date, Section 1.1 of the Agreement is amended to amend or add the following defined terms in proper
alphabetical order: 
 “Amortization Date” means July 1, 2016; provided however, if the Interest Only
Extension Conditions are satisfied, then January 1, 2017. 
 “Capital Stock Sale” means ZPC’s sale of
shares of its non-redeemable capital stock during the Measurement Period. 
 “Interest Only Extension Conditions”
means the occurrence to Lender’s reasonable satisfaction of each of the following events: (a) no default under any of the Loan Documents or Event of Default shall have occurred and be continuing, and (b) ZPC’s or Borrower’s
receipt during the Measurement Period of at least Fifty Million Dollars ($50,000,000) (i) from a Capital Stock Sale; or (ii) from a Strategic Partnership; or (iii) from a combination of (i) and (ii). 

“Maximum Term Loan Amount” means Fifteen Million and No/100 Dollars ($15,000,000). 

“Measurement Period” means the period of time beginning on June 23, 2015 and ending on March 15, 2016.

 “Strategic Partnership” means the execution and delivery during the Measurement Period of a license agreement,
joint venture agreement or other strategic partnership agreement between Borrower or ZPC and a third party company. 

“Term Loan Interest Rate” means (x) until June 23, 2015, for any day a per annum rate of interest equal to
the greater of (i) 12.05% plus the Prime Rate minus 5.25%, and (ii) 12.05%, and (y) on and after June 23, 2015, “Term Loan Interest Rate” means for any day a per annum rate of interest equal to the greater of
(i) 7.95% plus the Prime Rate minus 5.25%, and (ii) 7.95%. 

  
 2 

 “Term Loan Maturity Date” means December 1, 2018. 

“Warrant” means any warrant entered into between ZPC and HTGC in connection with the Loan, as may be amended,
restated or modified from time to time. 
 6.    As of the Effective Date, Section 2.1 of the Agreement is amended and restated as
follows, and a new Schedule A shall be deemed incorporated into the Agreement in the form of Schedule A, attached hereto: 

2.1    Term Loan. 

(a)    Advances. 

(i)    Subject to the terms and conditions of this Agreement, an Advance of $4,000,000 of the Term Loan
was made on the Closing Date. 
 (ii)    On June 23, 2015 and subject to the terms and conditions
of this Agreement, Borrower shall request from HTGC, and HTGC shall make to Borrower, an Advance under the Term Loan in an amount equal to the Maximum Term Loan Amount less the then outstanding principal amount from all prior Advances made. 

(iii)    No Lender shall be required to fund more than its pro rata share of the Term Loan as is
provided on Schedule A, hereto. 
 (b)    Advance Request. To obtain a Term Loan Advance, Borrower shall
complete, sign and deliver an Advance Request to Lender. Lender shall fund the Term Loan Advance in the manner requested by the Advance Request provided that each of the conditions precedent to such Term Loan Advance is satisfied as of the requested
Advance Date. 
 (c)    Interest. The principal balance of the Term Loan Advances shall bear interest
thereon from such Advance Date at the Term Loan Interest Rate based on a year consisting of 360 days, with interest computed daily based on the actual number of days elapsed. The Term Loan Interest Rate will float and change on the day the Prime
Rate changes from time to time, and Lender shall give Borrower timely notice of each change to the Prime Rate. 

(d)    Payment. 

(i)    On the first Business Day of each month beginning July 1, 2014, Borrower will pay interest on
the $4,000,000 Term Loan Advance made on 

  
 3 

 
or about the Closing Date. Repayment of such Term Loan Advance outstanding on December 31, 2014 shall be amortized in equal installments (based upon a 30 month amortization schedule) of
principal and interest (mortgage style), and payment of such installments shall begin on January 1, 2015 and continue on the first Business Day of each month thereafter through June 1, 2015. 

(ii)    On the first Business Day of each month beginning July 1, 2015, Borrower will pay interest on
all Term Loan Advances. Repayment of such Term Loan Advances outstanding on the day before the Amortization Date shall be amortized in equal installments (based upon a 30 month amortization schedule) of principal and interest (mortgage style), and
payment of such installments shall begin on the Amortization Date and continue on the first Business Day of each month thereafter, with all then outstanding amounts owed Lender hereunder to be paid on the Term Loan Maturity Date. 

(iii)    Unless accelerated pursuant to Section 7.15, the entire Term Loan principal balance, all
accrued but unpaid interest hereunder and any other outstanding Secured Obligations, shall be due and payable on the Term Loan Maturity Date. If accelerated pursuant to Section 7.15, the amount accelerated under Section 7.15 shall
immediately be due and payable. Borrower shall make all payments under this Agreement without setoff, recoupment or deduction and regardless of any counterclaim or defense. Lender will initiate debit entries to the Borrower’s account as
authorized on the ACH Authorization on each payment date of all periodic obligations payable to Lender under each Term Advance. 

7.    As of the Effective Date, Section 2.4 of the Agreement is amended and restated as follows: 

 

	    	2.4    Prepayment. At its option upon at least seven (7) Business Days prior notice to HTGC, Borrower may prepay all, but not less than all, of the outstanding Advances by paying the entire
principal balance, all accrued and unpaid interest thereon, together with a prepayment charge equal to the following percentage of the Advance amount being prepaid: if such Advance amounts are prepaid after June 23, 2015 but prior to
June 23, 2016, 1.0%; on or after June 23, 2016 but prior to June 23, 2017, 0.5% (each, a “Prepayment Charge”); and on or after June 23, 2017, no charge. Borrower agrees that the Prepayment Charge is a reasonable
calculation of Lender’s lost profits in view of the difficulties and impracticality of determining actual damages resulting from an early repayment of the Advances. On HTGC’s written request, Borrower shall prepay the outstanding amount of
all principal and accrued interest through the prepayment date and the Prepayment Charge upon a Change in Control. 

  
 4 

 8.    As of the Effective Date, Section 2.6 of the Agreement is amended and restated as
follows: 
 2.6    End of Term Charge. 

(a)    On the earliest to occur of (i) June 1, 2017, (ii) the date that Borrower prepays
the outstanding Secured Obligations, or (iii) the date that the Secured Obligations become due and payable, Borrower shall pay Lender a charge of $100,000. Notwithstanding the required payment date of such charge, it shall be deemed earned by
Lender as of the Closing Date. 
 (b)    On the earliest to occur of (i) the Term Loan Maturity
Date, (ii) the date that Borrower prepays the outstanding Secured Obligations, or (iii) the date that the Secured Obligations become due and payable, Borrower shall pay Lender a charge of $351,135.43. Notwithstanding the required payment
date of such charge, it shall be deemed earned by Lender as of June 23, 2015. 
 9.    Borrower shall use approximately $11,400,000
of the Advance made on June 23, 2015 to prepay all Indebtedness subordinated under the BMR Subordination Agreement, including the Subordinated Debt (as defined in the BMR Subordination Agreement), such payment to be made substantially
contemporaneously with the making of the Advance (the “BMR Prepayment”). Lender hereby consents to the BMR Prepayment and, in connection therewith, hereby waives the BMR Payment Notice, Lender’s right under Section 7.15(b)
of the Agreement to accelerate any or all of the entire Term Loan principal balance, all accrued but unpaid interest thereunder and any other outstanding Secured Obligations, and Lender’s rights under Section 6 of the Subordination
Agreement. 
 10.    This Amendment shall not be deemed to constitute an amendment to the Agreement except as expressly provided in
Sections 2 through 9, and all other terms and conditions of the Agreement shall remain in full force and effect. 
 11.    This
Amendment shall become effective on the occurrence of the following events (the “Effective Date”): 

a.    Execution and delivery by Borrower and Lender of a signed copy of this Amendment; 

b.    Borrower’s payment to Lender of a non-renewable facility charge of $75,000 (which amount may be deducted from
the proceeds made available to Borrower under the Agreement, as amended by this Amendment). The facility charge shall be deemed fully earned on payment regardless of the early termination of the Agreement; 

c.    Borrower’s payment of Lender’s legal costs and expenses, including attorneys’ fees, as provided in
Section 14; 
 d.    Delivery of a signed Warrant and First Amendment to Warrant from Borrower to Lender in a form
satisfactory to Lender; and 
 e.    Delivery of a signed supplement to the existing Joinder Agreement from ZPC in a
form satisfactory to Lender. 

  
 5 

 12.    Borrower hereby represents and warrants to Lender as follows: 

(a)    Borrower has all requisite power and authority to execute this Amendment and any other agreements or instruments
required hereunder and to perform all of its obligations hereunder, and this Amendment and all such other agreements and instruments have been duly executed and delivered by Borrower and constitute the legal, valid and binding obligation of
Borrower, enforceable in accordance with its terms, except as enforcement may be limited by equitable principles or by bankruptcy, insolvency, reorganization, moratorium, or similar laws relating to or limiting creditors’ rights generally. 

(b)    Other than the ZP Group LLC, Borrower has no other Subsidiaries. 

(c)    The execution, delivery and performance by Borrower of this Amendment and any other agreements or instruments
required hereunder have been duly authorized by all necessary corporate action and do not (i) require any authorization, consent or approval by any governmental department, commission, board, bureau, agency or instrumentality, domestic or
foreign, (ii) violate any provision of any law, rule or regulation or of any order, writ, injunction or decree presently in effect, having applicability to Borrower, or the articles of incorporation (or operating agreement, as applicable) or
by-laws of Borrower, or (iii) result in a breach of or constitute a default under any indenture or loan agreement or any other agreement, lease or instrument to which Borrower is a party or by which it or its properties may be bound or
affected. 
 (d)    No Event of Default exists under the Agreement, and all of Borrower’s representations and
warranties contained in the Agreement are correct on and as of the date hereof as though made on and as of such date, except to the extent that such representations and warranties relate solely to an earlier date. 

(e)    Except as may be described in ZPC’s current and periodic reports under the Securities Exchange Act of 1934, as
amended, no material amendments have been made to the Collaboration, Development and License Agreement between Borrower and Eli Lilly and Company, an Indiana corporation, dated as of November 21, 2014. 

13.    The execution of this Amendment and all other agreements and instruments related hereto shall not be deemed to be a waiver of any
Event of Default under the Agreement or a waiver of any breach or default under any of the other Loan Documents, whether or not known to Lender and whether or not existing on the date of this Amendment. 

14.    Borrower hereby reaffirms its agreement under Section 11.11 of the Agreement, to pay or reimburse Lender on demand for all
costs and expenses incurred by Lender in connection with the Loan Documents, including without limitation all reasonable fees and disbursements of legal counsel. Without limiting the generality of the foregoing, Borrower specifically agrees to pay
all reasonable fees and disbursements of counsel to Lender for the services performed by such counsel in connection with the preparation of this Amendment and the documents and instruments incidental hereto. Lender is authorized to initiate payment
of all such fees pursuant to the existing ACH Authorization previously delivered in connection with the Agreement. Borrower hereby agrees that Lender may, at any time or from time to time in its sole discretion and without further authorization by
Borrower, make a loan to Borrower under the Agreement, or apply the proceeds of any loan, for the purpose of paying any such fees, disbursements, costs and expenses. 

  
 6 

 15.    Release. 

(a)    Borrower, for itself and on behalf of its heirs, legal representatives, marital communities, and successors and
assigns, as applicable, hereby releases Lender and all of its Affiliates, shareholders, partners, predecessors, employees, officers, directors, attorneys, parent corporations, subsidiaries, agents, participants, assignees, servicers and receivers
(collectively, the “Released Parties”), except for obligations arising hereafter under this Amendment and the other Loan Documents, from any and all known and unknown claims, disputes, differences, liabilities and obligations of any
and every nature whatsoever that Borrower or any of them may have or claim, as of the date hereof or as of any prior date, against any one or more of the Released Parties arising from, based upon or related to the Loan Documents, or any other
agreement, understanding, action or inaction whatsoever with regard to the Loan Documents or any transaction or matter related thereto, including, without limitation, the origination and servicing of the Term Loan and the enforcement or attempted
enforcement of any rights or remedies for default or asserted default under the Loan Documents (collectively, the “Released Claims”). 

(b)    Borrower further acknowledges and agrees that the Released Claims include, among other things, all claims arising
out of or with respect to any and all transactions relating to the Loan Documents based on any fact, act, inaction, or other occurrence or nonoccurrence on or prior to the date hereof, including, without limitation, any breach of fiduciary duty or
duty of fair dealing, breach of confidence, breach of loan commitment, undue influence, duress, economic coercion, conflict of interest, negligence, bad faith, malpractice, violation of the Racketeer Influenced and Corrupt Organizations Act,
violation of any other statute, ordinance or regulation, intentional or negligent infliction of mental or emotional distress, tortious interference with contractual relations or prospective business advantage, tortious interference with corporate
governance, breach of contract, bad practices, unfair competition, libel, slander, conspiracy or any claim for wrongfully accelerating the Term Note or attempting to foreclose on, or obtain a receiver for, any collateral for the Term Note and all
statutory claims and causes of action of every nature. 
 (c)    In connection with the release contained in this
Section 15 (the “Release”), Borrower acknowledges that it is aware that it may hereafter discover facts in addition to or different from those that it now knows or believes to be true with respect to the Released Claims, but
that it is Borrower’s intention hereby fully, finally and forever to settle and release all claims, disputes, differences, liabilities and obligations arising from, based upon or related to the Loan Documents, known or unknown, suspected or
unsuspected, that exist as of the date of this Amendment, may exist as of the date of this Amendment or heretofore have existed by Borrower against any one or more of the Released Parties. In furtherance of that intention, the Release contained in
this Agreement shall be and remain in effect as a full and complete release notwithstanding the discovery of the existence of any such additional or different facts. 

  
 7 

 (d)    The Release contained in this Agreement shall be effective and
irrevocable upon the execution of this Agreement by Lender and Borrower and shall be deemed affirmed and restated upon, and effective as of, the Effective Date without any further documentation. 

(e)    BORROWER AGREES AND ACKNOWLEDGES THAT THE RELEASED CLAIMS ARE NOT LIMITED TO MATTERS THAT ARE KNOWN OR
DISCLOSED TO BORROWER AND THAT THE RELEASED CLAIMS INCLUDE ALL CLAIMS, DISPUTES, DIFFERENCES, LIABILITIES AND OBLIGATIONS THAT BORROWER DOES NOT KNOW OR SUSPECT TO EXIST AS OF THE DATE OF THIS AMENDMENT. BORROWER UNDERSTANDS THAT IT IS GIVING UP ALL
RIGHTS AND CLAIMS AGAINST LENDER AND THE OTHER RELEASED PARTIES, KNOWN OR UNKNOWN, THAT ARE IN ANY WAY RELATED TO THE PROPERTY OR THE LOAN ON OR PRIOR TO THE DATE OF THIS AMENDMENT. 

(f)    THE PARTIES SPECIFICALLY ALLOCATE THE RISK OF ANY MISTAKE IN ENTERING INTO THE RELEASE TO THE PARTY OR PARTIES
CLAIMING TO HAVE BEEN MISTAKEN. 
 (g)    Borrower acknowledges having read and understood and hereby waives the
benefits of Section 1542 of the California Civil Code, which provides as follows (and hereby waives the benefits of any similar law of the state that may be applicable): 

“A general release does not extend to claims which the creditor does not know or suspect to exist in his or her favor at the time of
executing the release, which if known by him or her must have materially affected his or her settlement with the debtor.” 

16.    This Amendment may be executed in any number of counterparts, each of which when so executed and delivered shall be deemed an
original and all of which counterparts, taken together, shall constitute one and the same instrument. The provisions of Section 11 of the Agreement shall be deemed incorporated herein by reference, mutatis mutandis. 

(signatures provided on the next page) 

  
 8 

 IN WITNESS WHEREOF, Borrower and Lender have duly executed and delivered this First Amendment to
Loan and Security Agreement as of the date and year first above written. 
  

			
	BORROWER:
	
	ZP OPCO, INC.
		
	Signature:		/s/ Vikram Lamba
	By:		Vikram Lamba
	Title:		President

 Accepted in Palo Alto, California:  

 

			
	LENDER:
	
	 HERCULES TECHNOLOGY GROWTH
 CAPITAL,
INC.

		
	Signature:		/s/ Ben Bang
	Print Name:		Ben Bang
	Title:		Associate General Counsel

  

			
	HERCULES CAPITAL FUNDING TRUST 2014-1
		
	Signature:		/s/ Ben Bang
	Print Name:		Ben Bang
	Title:		Associate General Counsel

  
 9 

 Schedule A 

Commitments 
 COMMITMENTS

					
	 LENDER
	  	TERM COMMITMENT	 
	 HERCULES CAPITAL FUNDING TRUST 2014-1
	  	$	3,295,485.55	  
	 HERCULES TECHNOLOGY GROWTH CAPITAL, INC
	  	$	11,704,514.45	  
	 TOTAL COMMITMENTS
	  	$	15,000,000	  

  
 10

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