Document:

EX-10.12

 Exhibit 10.12 

OFFICE LEASE 
 by and
between 
 T-C 33 ARCH STREET LLC 

a Delaware limited liability company 

(“Landlord”) 

and 
 KARUNA
PHARMACEUTICALS, INC. 
 a Delaware corporation 

(“Tenant”) 

Dated as of 
 November
2, 2018 
  

 TABLE OF CONTENTS 

 

							
	 LEASE OF PREMISES
	  	 	1	 
	 BASIC LEASE PROVISIONS
	  	 	1	 
	 STANDARD LEASE PROVISIONS
	  	 	4	 
	 1.
	 	TERM	  	 	4	 
	 2.
	 	BASE RENT AND SECURITY DEPOSIT	  	 	4	 
	 3.
	 	ADDITIONAL RENT	  	 	7	 
	 4.
	 	IMPROVEMENTS AND ALTERATIONS	  	 	15	 
	 5.
	 	REPAIRS	  	 	18	 
	 6.
	 	USE OF PREMISES	  	 	19	 
	 7.
	 	UTILITIES AND SERVICES	  	 	22	 
	 8.
	 	INSURANCE	  	 	26	 
	 9.
	 	FIRE OR CASUALTY	  	 	30	 
	 10.
	 	EMINENT DOMAIN	  	 	31	 
	 11.
	 	ASSIGNMENT AND SUBLETTING	  	 	32	 
	 12.
	 	DEFAULT	  	 	36	 
	 13.
	 	ACCESS; CONSTRUCTION	  	 	41	 
	 14.
	 	BANKRUPTCY	  	 	42	 
	 15.
	 	SUBSTITUTION OF PREMISES	  	 	43	 
	 16.
	 	SUBORDINATION; ATTORNMENT; ESTOPPEL CERTIFICATES	  	 	43	 
	 17.
	 	SALE BY LANDLORD; TENANT’S REMEDIES; NONRECOURSE LIABILITY	  	 	44	 
	 18.
	 	PARKING: COMMON AREAS	  	 	46	 
	 19.
	 	MISCELLANEOUS	  	 	47	 

  
  

LIST OF EXHIBITS 
  

			
	Exhibit A-1	  	Floor Plan(s)
		
	 Exhibit A-2
	  	Legal Description of the Land
		
	 Exhibit B
	  	Work Letter
		
	 Exhibit C
	  	Items Purchased from Juniper Pharmaceuticals
		
	 Exhibit D
	  	Form Tenant Estoppel Certificate
		
	 Exhibit E
	  	Tenant’s Commencement Letter
		
	 Exhibit F
	  	Form of Confidentiality Agreement

  

  
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 OFFICE LEASE 

THIS OFFICE LEASE (this “Lease”) is made between T-C 33 Arch Street LLC, a Delaware limited liability company
(“Landlord”), and the Tenant described in Item 1 of the Basic Lease Provisions. 
 LEASE OF PREMISES

 Landlord hereby leases to Tenant and Tenant hereby leases from Landlord, subject to all of the terms and conditions set forth
herein, those certain premises (the “Premises”) described in Item 3 of the Basic Lease Provisions and as shown in the drawing attached hereto as Exhibit A-1. The Premises are located in the Building
described in Item 2 of the Basic Lease Provisions. The Building is located on that certain land (the “Land”) more particularly described on Exhibit A-2 attached hereto, which is also improved with
landscaping and other improvements, fixtures and common areas and appurtenances now or hereafter placed, constructed or erected on the Land. 

BASIC LEASE PROVISIONS 
  

							
	 1.  Tenant:
	  	Karuna Pharmaceuticals, Inc., a Delaware corporation (“Tenant”)
		
	 2.  Building:
	  	33 Arch Street 33 Arch Street Boston, Massachusetts 02110
		
	 3.  Description of Premises:
	  	 Suite 3110 comprising approximately 7,050 rentable square feet on the thirty first (31st) floor of the Building.
  
 The
Premises do not include the area above dropped ceilings, below the upper surface of floor slabs or the areas outside of the inner surface of interior walls and plate glass (the areas above dropped ceilings up to the underside of the slab above such
dropped ceiling and outside the inner surface of interior walls until the edge of the Premises are referred to in this Lease as “Installation Areas”).

		
	     Rentable Area:
	  	Approximately 7,050 rentable square feet
		
	     Rentable Area of Building:
	  	603,309 rentable square feet (subject to Paragraph 18)
		
	 4.  Tenant’s Proportionate Share:
	  	1.169% (7,050 rsf /603,309 rsf) (See Paragraph 3)

							
	  
 5.  Base Rent:
	  	 Period
	  	 Annual Base Rent
	  	 Monthly  

Installment

	  	Commencement Date—day before the Rent Commencement Date*	  	$           0.00	  	$         0.00
	  	Lease Year 1	  	$493,500.00	  	$41,125.00
	  	Lease Year 2	  	$500,550.00	  	$41,712.50
	  	Lease Year 3	  	$507,600.00	  	$42,300.00
	  	Lease Year 4	  	$514,650.00	  	$42,887.50

  
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		  	 Tenant shall have no obligation to pay Annual Base Rent for the period commencing as of the Commencement Date, and expiring at
the expiration of the day before the Rent Commencement Date (the “Rent Abatement Period”). During the Rent Abatement Period, only Annual Base Rent shall be abated, and all Additional Rent (as hereinafter defined) and other costs and
charges specified in the Lease shall remain as due and payable pursuant to the provisions of the Lease.
  

As used in this Lease, “Lease Year” means each period of one year during the Term commencing on the Rent Commencement Date or on any
anniversary thereof, or, if such Rent Commencement Date does not fall on the first day of a calendar month, the first Lease Year shall consist of the partial calendar month following the Rent Commencement Date and the succeeding twelve full calendar
months, and each succeeding Lease Year shall consist of a one-year period commencing on the first day of the calendar month following the calendar month in which such Rent Commencement Date fell.

 
 (See Paragraph 2)

		
	 6.  Installment of Base Rent Payable Upon Execution:
	  	$41,125.00
		
	 7.  Security Deposit Payable Upon Execution:
	  	$123,375.00, in the form of a Letter of Credit, subject to possible reduction pursuant to Paragraph 2(c) (See Paragraph 2(c))
		
	 8.  Base Year for Operating Expenses:

 
     Base Year for Real
Estate Taxes:
	  	 Calendar year 2019 (See Paragraph 3)
  

Fiscal tax year 2019 (See Paragraph 3)

		
	 9.  Term:
	  	A period of fifty-one (51) calendar months (plus the partial month, if any, immediately following the Commencement Date), commencing on the Commencement Date and terminating on the Termination Date. (See Paragraph
1).
		
	 10.  Commencement Date:
	  	The date on which Landlord shall deliver possession of the Premises to Tenant with Landlord’s Work Substantially Complete, in accordance with the provisions of this Lease. Landlord estimates that such date shall be
on or about December 1, 2018 (the “Estimated Commencement Date”) (See Paragraph 1 and Exhibit B)
		
	 11.  Rent Commencement Date
	  	The date that is three (3) months following the Commencement Date. (See Paragraph 1).

  
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	 12.  Termination Date:
	  	The date that is fifty-one (51) calendar months (plus the partial month, if any) immediately following the Commencement Date.
		
	 13.  Broker(s) (See Paragraph 19(k))

 
     Landlord’s
Broker:
  

    Tenant’s Broker:
	  	 CBRE-N.E. Partners, L.P.
  

Jones Lang LaSalle

		
	 14.  Number of Parking Spaces:
	  	Three (3) parking spaces on the terms described in Paragraph 18.
		
	 15.  Address for Notices:

 
 To:  TENANT:

 
 Prior to occupancy of the Premises:

 
 Karuna Pharmaceuticals, Inc.

c/o PureTech Health LLC
 501 Boylston Street

Suite 6102 Boston, Massachusetts
 02116

Attn: President
  

After occupancy of the Premises:
  

Karuna Pharmaceuticals, Inc.
 33 Arch Street, Suite 3110

Boston, Massachusetts 02110
 Attn: President

 
 With a copy to:

 
 Anderson & Kreiger LLP

50 Milk Street, 21st Floor

Boston, Massachusetts 02109
 Attn: David L. Wiener, Esq.
	  	 To: LANDLORD:
  

Office of the Building
  

T-C 33 Arch Street LLC
 33 Arch Street

Boston, Massachusetts 02110
 Attention: Property Manager

 
 With a copy to:

 
 T-C 33 Arch Street LLC

c/o TH Real Estate
 100 Federal Street, 33rd Floor
 Boston, Massachusetts 02110

Attention: William K. Abramowitz

		
	 16.  Address for Payment of Rent:
	  	 All payments payable under this Lease shall be sent to

Landlord at:
 Office of the Building

33 Arch Street
 Boston, Massachusetts 02110

 
 Or to such other address as Landlord may designate to Tenant from time to time in
writing.

		
	 17.  Guarantor:
	  	N/A
		
	 18.  Tenant Improvement Allowance:
	  	$141,000.00. (See Paragraph 4(a)).
		
	 19.  The “State”:
	  	The Commonwealth of Massachusetts.

 This Lease consists of the foregoing introductory paragraphs and Basic Lease Provisions, the provisions of the Standard Lease
Provisions (the “Standard Lease Provisions”) (consisting of Paragraph 1 through Paragraph 19 which follow) and Exhibits A-1 through Exhibit A-2 and Exhibits B through Exhibit F, all of which
are incorporated herein by this reference. In the event of any conflict between the provisions of the Basic Lease Provisions and the provisions of the Standard Lease Provisions, the Standard Lease Provisions shall control. 

 

  
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 STANDARD LEASE PROVISIONS 

1. TERM. 
 (a)
The Term of this Lease shall commence on the Commencement Date (as defined in Item 10 of the Basic Lease Provisions) and the Rent (defined below) shall commence on the Rent Commencement Date (as defined in
Item 11 of the Basic Lease Provisions). Unless earlier terminated in accordance with the provisions hereof, the Term of this Lease shall be the period shown in Item 9 of the Basic Lease Provisions. As used
herein, “Lease Term” shall mean the Term referred to in Item 9 of the Basic Lease Provisions, subject to any early termination thereof and the “Expiration Date” shall be the last day of the Lease
Term. Unless Landlord is terminating this Lease prior to the Termination Date (as defined in Item 12 of the Basic Lease Provisions) in accordance with the provisions hereof, Landlord shall not be required to provide notice to
Tenant of the Expiration Date. This Lease shall be a binding contractual obligation effective upon execution and delivery hereof by Landlord and Tenant, notwithstanding the later commencement of the Initial Term of this Lease. 

(b) The Premises will be delivered to Tenant on the Commencement Date. If the Commencement Date is delayed, this Lease shall not be void or
voidable, nor shall Landlord be liable to Tenant for any loss or damage resulting therefrom. 
 (c) Upon Landlord’s preparation and
delivery to Tenant of Tenant’s Commencement Letter in the form of Exhibit E attached hereto (the “Commencement Letter”), and, absent manifest error, Tenant shall acknowledge the same by executing a copy and shall
return it to Landlord. If, within thirty (30) days of its receipt from Landlord, Tenant (i) fails to sign and return the Commencement Letter to Landlord or (ii) fails to identify in writing to Landlord the terms and provisions of the
Commencement Letter which are incorrect, the Commencement Letter as sent by Landlord shall be deemed to have correctly set forth the Commencement Date and the other matters addressed in the Commencement Letter. Failure of Landlord to send the
Commencement Letter shall have no effect on the Commencement Date. 
 2. BASE RENT AND SECURITY DEPOSIT. 

(a) Except as expressly provided to the contrary in this Lease, Tenant agrees to pay with respect to each calendar month (and proportionately
on a per diem basis for any partial calendar month of the Lease Term) from and after the Rent Commencement Date as Base Rent (“Base Rent”) for the Premises the sums shown for such periods in Item 5 of the
Basic Lease Provisions. 
 (b) Except as expressly provided to the contrary in this Lease, Base Rent shall be payable in consecutive monthly
installments, in advance, without demand, deduction or offset, commencing on the Rent Commencement Date and continuing on the first day of each calendar month thereafter until the expiration of the Lease Term. The first full monthly installment of
Base Rent shall be payable upon Tenant’s execution of this Lease and shall be credited against the Rent next coming due. The obligation of Tenant to pay Rent and other sums to Landlord and the obligations of Landlord under this Lease are
independent obligations. In the event Landlord delivers possession of the Premises to Tenant prior to the Commencement Date, Tenant agrees it 

  
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shall be bound by and subject to all terms, covenants, conditions and obligations of this Lease during the period if any between the date possession is delivered and the Commencement Date, other
than the payment of Base Rent, Operating Expenses, Additional Rent and Taxes Additional Rent in the same manner as if delivery had occurred on the Commencement Date. 

(c) 
 (i) Tenant shall deliver to
Landlord simultaneously with the delivery of this Lease as executed by Tenant, as collateral for the full performance by Tenant of all of its obligations under this Lease and for all losses and damages Landlord may suffer as a result of
Tenant’s failure to comply with one or more provisions of this Lease, a Letter of Credit (hereinafter defined) containing the terms required herein, in the face amount of $123,375.00 (the “Letter of Credit Amount”). 

“Letter of Credit” shall mean a clean, irrevocable, non-documentary and unconditional letter of credit, permitting multiple
and partial draws thereon, and otherwise in form acceptable to Landlord in its sole, reasonable discretion issued by and drawable upon a commercial bank (the “Issuing Bank”), which is satisfactory to Landlord and which satisfies
both the Minimum Rating Agency Threshold (as hereinafter defined) and the Minimum Capital Threshold (as hereinafter defined). The “Minimum Rating Agency Threshold” shall mean that the Issuing Bank has outstanding unsecured,
uninsured and unguaranteed senior long-term indebtedness that is then rated (without regard to qualification of such rating by symbols such as “+” or “-” or numerical notation) “Baa” or better by Moody’s Investors
Service, Inc. and/or “BBB” or better by Standard & Poor’s Rating Services, or a comparable rating by a comparable national rating agency designated by Landlord in its discretion. The “Minimum Capital
Threshold” shall mean that the Issuing Bank has combined capital, surplus and undivided profits of not less than $2,000,000,000. 

If, at any time or from time to time, Landlord determines that an Issuing Bank (i) no longer satisfies the Minimum Rating Agency
Threshold, (ii) no longer satisfies the Minimum Capital Threshold, (iii) has been seized or closed by the Federal Reserve Board, the Federal Deposit Insurance Corporation, the Office of the Comptroller of the Currency, or another
governmental or regulatory agency or authority, (iv) has become insolvent, or (v) is unwilling or unable to honor the Letter of Credit or to perform its obligations to honor a draw upon the Letter of Credit, then within thirty
(30) days after demand, Tenant shall deliver to Landlord a replacement Letter of Credit, issued by a replacement Issuing Bank which satisfies the Minimum Rating Agency Threshold and the Minimum Capital Threshold and is otherwise satisfactory to
Landlord in its discretion. 
 Tenant shall cause each Letter of Credit to be continuously maintained in effect (whether through
replacement, renewal or extension) in the Letter of Credit Amount through the date (the “Final LC Expiration Date”) that is 30 days after the scheduled expiration date of the Term or any renewal Term. If the Letter of Credit held by
Landlord expires earlier than the Final LC Expiration Date (whether by reason of a stated expiration date or a notice of termination or nonrenewal given by the issuing bank), Tenant shall deliver a new Letter of Credit or certificate of renewal or
extension (a “Renewal or Replacement LC”) to Landlord not later than 30 days prior to the expiration date of the Letter of Credit then held by Landlord. Any Renewal or Replacement LC shall comply with all of the provisions of this
Paragraph 2(c), shall be irrevocable, transferable and shall remain in effect (or be automatically renewable) through the Final LC Expiration Date upon the same terms as the expiring Letter of Credit or such other terms as may be acceptable
to Landlord in its sole, reasonable discretion. 
  

  
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 (ii) Drawings under Letter of Credit. Upon default by Tenant, Landlord may, without
prejudice to any other remedy provided in this Lease or by Law, draw on the Letter of Credit and use all or part of the proceeds to satisfy any amounts due to Landlord from Tenant. In addition, if Tenant fails to furnish a Renewal or Replacement LC
complying with all of the provisions of this Paragraph 2(c) at least 30 days prior to the stated expiration date of the Letter of Credit then held by Landlord, Landlord may draw upon such Letter of Credit and hold the proceeds thereof (and
such proceeds need not be segregated) in accordance with the terms of this Paragraph 2(c) (the “LC Proceeds Account”). 

(iii) Use of Proceeds by Landlord. The proceeds of the Letter of Credit shall constitute Landlord’s sole and separate property (and not
Tenant’s property or the property of Tenant’s bankruptcy estate) and Landlord may immediately upon any draw (and without notice to Tenant) apply or offset the proceeds of the Letter of Credit: (a) against any Rent payable by Tenant
under this Lease that is not paid when due; (b) against all losses and damages that Landlord has suffered or that Landlord reasonably estimates that it may suffer as a result of Tenant’s failure to comply with one or more provisions of
this Lease; (c) against any costs incurred by Landlord in connection with the Lease (including reasonable attorneys’ fees); and (d) against any other amount that Landlord may spend or become obligated to spend by reason of
Tenant’s Default. Provided Tenant has performed all of its obligations under this Lease, Landlord agrees to pay to Tenant within 30 days after the Final LC Expiration Date the amount of any proceeds of the Letter of Credit received by Landlord
and not applied as allowed above; provided, that if prior to the Final LC Expiration Date a voluntary petition is filed by Tenant, or an involuntary petition is filed against Tenant by any of Tenant’s creditors, under the Federal Bankruptcy
Code, then Landlord shall not be obligated to make such payment in the amount of the unused Letter of Credit proceeds until either all preference issues relating to payments under this Lease have been resolved in such bankruptcy or reorganization
case or such bankruptcy or reorganization case has been dismissed, in each case pursuant to a final court order not subject to appeal or any stay pending appeal. 

(iv) Additional Covenants of Tenant. If, as result of any application or use by Landlord of all or any part of the Letter of Credit, the amount
of either Letter of Credit shall be less than the Letter of Credit Amount, Tenant shall, within 5 business days thereafter, provide Landlord with additional letter(s) of credit in an amount equal to the deficiency (or a replacement letter of credit
in the total Letter of Credit Amount), and any such additional (or replacement) letter of credit shall comply with all of the provisions of this Paragraph 2(c), and if Tenant fails to comply with the foregoing, notwithstanding anything to the
contrary contained in this Lease, the same shall constitute an incurable Default by Tenant. Tenant further covenants and warrants that it will neither assign nor encumber the Letter of Credit or any part thereof and that neither Landlord nor its
successors or assigns will be bound by any such assignment, encumbrance, attempted assignment or attempted encumbrance. 

  
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 (v) Tenant shall be entitled to a reduction in the amount of the Letter of Credit to
$41,125.00 on the third (3rd) anniversary of the Rent Commencement Date if there exists no uncured Event of Default under the terms of this Lease, and (ii) Landlord has not applied the
Letter of Credit, or any portion thereof, to Landlord’s damages arising from any default on the part of Tenant, whether or not Tenant has restored the amount so applied by Landlord. If an Event of Default exits under the Lease as of the third
(3rd) anniversary of the Rent Commencement Date and thereafter Tenant has caused the Event of Default to be cured, then, provided that Landlord shall not have applied the Letter of Credit, or
any portion thereof, to Landlord’s damages arising from any default on the part of Tenant, Tenant shall be entitled to such reduction at such time thereafter as no uncured Event of Default exists. 

If Tenant believes that it has satisfied all the conditions precedent to a reduction in the amount of the Letter of Credit, then it shall
request such reduction in writing to Landlord. If Landlord determines that all of the aforesaid conditions are met, the Security Deposit shall be so reduced in accordance with this Paragraph 2(c)(v). No Letter of Credit shall automatically
reduce, but any reduction in the amount thereof shall require Landlord’s prior written notice to the issuer of the Letter of Credit of the reduced amount. Promptly after Landlord’s receipt of Tenant’s written request for a reduction
as described above, Landlord shall determine whether such a reduction is permitted in accordance with this Paragraph 2(c)(v), and if it is, Landlord shall promptly notify the issuer of the Letter of Credit in writing of the amount to which
the Letter of Credit shall be reduced, and Landlord shall at its election either (i) exchange the Letter of Credit initially delivered hereunder by Tenant for a replacement Letter of Credit delivered by Tenant which reduces the amount of the
Letter of Credit and otherwise in strict conformity with the requirements herein, or (ii) permit the Issuing Bank to amend the Letter of Credit to reduce the amount of the Letter of Credit in accordance with this Paragraph 2(c)(v). 

(d) The parties agree that for all purposes hereunder the Premises and the Building shall be stipulated to contain the number of square feet of
Rentable Area respectively described in Item 3 of the Basic Lease Provisions. 
 (e) Base Rent shall be paid to Landlord
absolutely net of all costs and expenses. The provisions for payment of Operating Expenses by means of periodic payment of Tenant’s Proportionate Share of estimated Operating Expenses and the year end adjustment of such payments are intended to
pass on to Tenant and reimburse Landlord for Tenant’s Proportionate Share of all costs and expenses of the nature described in Paragraph 3 of this Lease. 

3. ADDITIONAL RENT 

(a) If Operating Expenses (defined below) for the Land and Building for any calendar year during the Lease Term exceed Base Operating Expenses
(defined below), Tenant shall pay to Landlord, concurrent with each installment of Base Rent as additional rent (together with all other amounts payable under this Lease, “Operating Expenses Additional Rent”) an amount equal to
Tenant’s Proportionate Share (defined below) of such excess (“Operating Expenses Excess”). If Real Estate Taxes (defined below) for the Land and Building for any calendar year during the Lease Term exceed Base Real Estate Taxes
(defined below), Tenant shall pay to Landlord as additional rent (“Taxes Additional Rent”) an amount equal to Tenant’s Proportionate Share of such excess (“Taxes Excess”). The term “Additional
Rent” shall mean, collectively, the Operating Expenses Additional Rent and Taxes Additional Rent. 

  
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 (b) “Tenant’s Proportionate Share” is, subject to the provisions of
Paragraph 18, the percentage number described in Item 4 of the Basic Lease Provisions. Tenant’s Proportionate Share represents, subject to the provisions of Paragraph 18, a fraction, the numerator of which is
the number of square feet of Rentable Area in the Premises and the denominator of which is the number of square feet of Rentable Area for lease to third parties in the Building, as determined by Landlord pursuant to Paragraph 18. 

(c) “Base Operating Expenses” means all Operating Expenses incurred or payable by Landlord during the calendar year specified
as Tenant’s Base Year for Operating Costs in Item 8 of the Basic Lease Provisions. The term “Base Real Estate Taxes” shall mean all Real Estate Taxes incurred or payable by Landlord during the calendar year
specified as Tenant’s Base Year for Real Estate Taxes in Item 8 of the Basic Lease Provisions. 
 (d)
“Operating Expenses” means all costs, expenses and obligations incurred or payable by Landlord in connection with the operation, ownership, management, repair or maintenance of the Land and Building during or allocable to the Lease
Term, including without limitation, the cost of services and utilities (including taxes and other charges incurred in connection therewith) provided to the Premises (other than those separately metered utilities for which Tenant is responsible under
this Lease), the Building or the Land, including, without limitation, water, power, gas, sewer, waste disposal, telephone and cable television facilities, fuel, supplies, equipment, tools, materials, service contracts, janitorial service, waste and
refuse disposal, window cleaning, maintenance and repair of sidewalks and Building exterior and services areas, gardening and landscaping; insurance, including, but not limited to, public liability, fire, property damage, wind, hurricane,
earthquake, terrorism, flood, rental loss, rent continuation, boiler machinery, business interruption, contractual indemnification and property/casualty coverage insurance for the Land and/or Building and such other insurance as is carried by
Landlord in its discretion, and the deductible portion of any insured loss otherwise covered by such insurance; the cost of compensation, including employment, welfare and social security taxes, paid vacation days, disability, pension, medical and
other fringe benefits of all persons (including independent contractors) who perform services connected with the operation, maintenance, repair or replacement of the Land and/or Building at or below the level of building manager (as described
below); any association assessments, costs, dues and/or expenses relating to the Land and/or Building; personal property taxes on and maintenance and repair of equipment and other personal property used in connection with the operation, maintenance
or repair of the Land and/or Building; repair and replacement of window coverings provided by Landlord in the premises of tenants in the Building; such reasonable auditors’ fees and legal fees as are incurred in connection with the operation,
maintenance or repair of the Land and/or Building, except as excluded below; a property management fee, which fee shall not exceed 3% of the gross revenue of the Building (and which fee may be imputed if Landlord has internalized management or
otherwise acts as its own property manager); the maintenance of any easements or ground leases benefiting the Land and/or Building, whether by Landlord or by an independent contractor; a reasonable allowance for depreciation of personal property
used in the operation, maintenance or repair of the Land and/or Building; license, permit and inspection fees unless incurred as a result of violations of Laws (defined below) by Landlord or another tenant in the Building; all costs and expenses
required by any governmental or quasi- governmental authority to make the Land or the Building conform with applicable law not in effect as of the Date of this Lease, for any reason, including capital improvements, whether capitalized or expensed
for accounting or tax purposes, and the cost of any capital improvements 

  
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made to the Land or Building by Landlord which are (i) intended to effect economies in the operation or maintenance of the Land or building, reduce future Operating Expenses, enhance the
safety or security of the Land or Buildings or its occupants or reduce the environmental impact of the Building and (ii) and the costs to replace (rather than repair which would be included in any event) items which Landlord would be obligated
to repair under the Lease (provided that with respect to all such costs which are capital in nature there shall be included in any calendar year only the amount of the straight-line amortization of such cost over the lesser of (A) the useful
life of the associated item and (B) the Payback Period (as hereinafter defined), together in either case with interest thereon at the rate of eight percent (8%) per annum or such higher rate as may have been paid by Landlord on funds
borrowed for the purpose of funding such improvements); the cost of air conditioning, heating, ventilating, plumbing, elevator maintenance and repair (to include the replacement of components which are in the nature of repairs as hereinafter
described) and other mechanical and electrical systems repair and maintenance (including the replacement of components of the systems which are in the nature of repairs and are not required to be considered capital expenses under first class
office building accounting standards even if such item might be classified as a capital expenditure under generally accepted accounting principles (by way of example, a fan motor in an HVAC distribution box might be a capital expense under generally
accepted accounting principles but would be considered as a repair under first class office building accounting standards as in use by the Building)); sign maintenance; and Common Area (defined below) repair, resurfacing, operation and maintenance;
the reasonable cost for temporary lobby displays and events commensurate with the operation of a similar class building, and the cost of providing security services, if any, deemed appropriate by Landlord from time to time. “Payback
Period” means the period of time that Landlord reasonably estimates in accordance with generally accepted accounting principles it will take for the cost savings resulting from a capital improvement to equal the total cost of the capital
improvement. 
 The following items shall be excluded from Operating Expenses: 

(i) leasing commissions, attorneys’ fees, advertising costs, promotional costs, public relation fees, and all other costs
and disbursements and other expenses incurred in connection with leasing, renovating or improving vacant space in the Building for tenants or prospective tenants of the Building; 

(ii) costs (including permit, license and inspection fees) incurred in renovating or otherwise improving or decorating,
painting or redecorating space for tenants or vacant space; 
 (iii) Landlord’s costs of any services provided to
tenants to the extent (i) comparable services are not provided to Tenant, or (ii) Landlord is entitled to be reimbursed by such tenants as an additional charge or rental over and above the base rent and operating expenses payable under the
lease with such tenant or other occupant; 
 (iv) any depreciation or amortization of the Building or equipment used in
connection with the operation or maintenance of the Building except as expressly permitted herein; 

  
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 (v) costs incurred due to a violation of Law (defined below) by Landlord
relating to the Land or Building; 
 (vi) interest on debt or amortization payments on any mortgages or deeds of trust or any
other debt for borrowed money, except as expressly permitted herein; 
 (vii) repairs or other work occasioned by fire,
windstorm or other work to the extent paid for through insurance or condemnation proceeds (excluding any deductible); 

(viii) legal fees and expenses or other professional or consulting fees and expenses incurred for (i) negotiating lease
terms for prospective tenants, (ii) negotiating termination or extension of leases with existing tenants, (iii) proceedings against any other specific tenant, including, without limitation, rent collection proceedings; (iv) the
purchase or sale of the Building or (v) negotiating or enforcing any ground lease related to all or any portion of the Land; 

(ix) except as expressly set forth above in this Paragraph 3(d), the cost of alterations, additions, capital
improvements, equipment replacements and other items which under generally accepted accounting principles are properly classified as capital expenditures; it being further understood and agreed to by the parties that, with respect to capital
expenditures for the purpose of reducing Operating Expenses, the annual amortization to be included in Operating Expenses shall not exceed Landlord’s reasonable estimate of the annual savings realized by such capital expenditures; 

(x) ground rent or similar payments to a ground lessor, if any; 

(xi) repairs necessitated by the negligence or willful misconduct of Landlord; 

(xii) compensation paid to officers, executives or employees above the level of building manager (however titled) of Landlord
and/or Landlord’s property manager; 
 (xiii) overtime HVAC costs or excess electricity costs that are separately
charged to Building tenants, including without limitation Tenant; 
 (xiv) operating expenses which are individually
responsibility of Tenant or of other tenants and the cost of performing additional services that are separately charged to Building tenants, including without limitation Tenant; 

(xv) any amounts payable by Landlord as a result of Landlord’s failure to perform its obligations on a timely basis, or by
way of indemnity or for damages or which constitute a fine, interest, or penalty, including interest or penalties for any late payments of Operating Expenses; 

(xvi) any costs representing an amount paid for services or materials to a related person, firm, or entity to the extent such
amount exceeds the amount that would be paid for such services or materials at the then existing market rates to an unrelated person, firm or corporation; 

  
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 (xvii) the cost of overtime or other expenses to Landlord in curing its
defaults; 
 (xviii) income and franchise taxes of Landlord; 

(xix) any bad debt loss, rent loss, or reserves for bad debts or rent loss; 

(xx) attorneys’ fees and other costs and expenses awarded to any tenant pursuant to any lease, or incurred as a result of
Landlord’s failure to maintain any insurance required of Landlord under this Lease or any other lease; 
 (xxi) costs
associated with the operation of the legal entity which constitutes the Landlord or persons or entities which constitute or are affiliated with the Landlord or its partners or members, as such costs are separate and apart from costs associated with
the operation of the Building, including legal entity formation, internal entity accounting and internal legal matters; 

(xxii) costs resulting from Landlord’s breach of this Lease; 

(xxiii) costs imposed by a governmental authority as a result of a violation of any Laws where such violation is not caused by
Tenant; 
 (xxiv) the cost of any electric service provided to any leased space in the Building (i.e., other than to Common
Areas); 
 (xxv) costs arising from the removal of Hazardous Materials (as hereinafter defined), in, about or below the
Building or the property due to governmental regulations enacted prior to the date hereof; 
 (xxvi) reserves with respect to
any anticipated Operating Expenses; 
 (xxvii) costs recoverable under any warranties carried by Landlord; 

(xxviii) political contributions; 

(xxix) Landlord’s advertising and promotional expenses for the Building; 

(xxx) the cost of the improvements to the Building’s lobby presently planned by the Landlord; 

(xxxi) the cost of the repair, maintenance, and operation of the Parking Garage (defined below); and 

(xxxii) artwork. 

  
 -11- 

 (e) “Real Estate Taxes”. Any form of assessment, license fee, license tax,
business license fee, levy, charge, improvement bond, tax, water and sewer rents and charges, utilities and communications taxes and charges or similar or dissimilar imposition imposed by any authority having the direct power to tax, including any
city, county, state or federal government, or any school, agricultural, lighting, drainage or other improvement or special assessment district thereof, or any other governmental charge, general and special, ordinary and extraordinary, foreseen and
unforeseen, which may be assessed against any legal or equitable interest of Landlord in the Premises, Building or the Land. Real Estate Taxes shall also include, without limitation: 

(i) any hereafter adopted assessment, tax, fee, levy or charge in substitution, partially or totally, of any assessment, tax, fee, levy or
charge previously included within the ad valorem real property taxes. It is the intention of Tenant and Landlord that all such new and increased assessments, taxes, fees, levies and charges be included within the definition of “Real Estate
Taxes” for the purposes of this Lease; 
 (ii) any assessment, tax, fee, levy or charge allocable to or measured by the area of the
Premises or other premises in the Building or the rent payable by Tenant hereunder or other tenants of the Building, including, without limitation, any gross receipts tax or excise tax levied by state, city or federal government, or any political
subdivision thereof, with respect to the receipt of such rent, or upon or with respect to the possession, leasing, operation, management, maintenance, alteration, repair, use or occupancy by Tenant of the Premises, or any portion thereof but not on
Landlord’s other operations; 
 (iii) any business improvement district assessments or charges, or PILOT (i.e., payments in lieu of
taxes payments); and with respect to any betterment assessments or other special assessments included in Real Estate Taxes, Landlord shall be deemed to have elected to pay the same over the longest period permitted by law (whether or not Landlord
actually elects to do so) and only the annual amount so payable shall be included in Real Estate Taxes for any fiscal year; 
 (iv) any
assessment, tax, fee, levy or charge by any governmental agency related to any transportation plan, fund or system (including assessment districts) instituted within the geographic area of which the Land is a part; and/or 

(v) any costs and expenses (including, without limitation, reasonable attorneys’ fees) incurred in attempting to protest, reduce or
minimize Real Estate Taxes. 
 Notwithstanding anything to the contrary contained in this Lease, “Real Estate Taxes” shall not
include any inheritance, estate, succession, transfer gift, franchise, corporation, income or profit tax or capital levy that is or may be imposed upon Landlord. Real Estate Taxes shall also not include interest and penalties for late payment so
long as Tenant has paid Tenant’s Proportionate Share of Tax Excess on account of such Real Estate Taxes on or before the date when payable to Landlord. In the event that Landlord receives an abatement or refund of Real Estate Taxes, the Real
Estate Taxes for the year or years for which the abatement was obtained shall be recalculated by subtracting the amount of the abatement or refund for such year (after first deducting therefrom the costs and expenses of obtaining such abatement or
refund, including attorneys’ fees). The Tax Excess and Tenant’s Proportionate Share of the Tax Excess for such 

  
 -12- 

 
years shall be adjusted accordingly and Tenant shall receive a credit for any overpayment of Taxes Additional Rent against the next payment(s) becoming due on account of Tenant’s
Proportionate Share of Tax Excess. If upon the expiration of the Lease any credits remain after application to any amounts that may become payable as aforesaid, Landlord shall refund the balance of the overpayment to Tenant. 

(f) Operating Expenses for any calendar year during which actual occupancy of the Building is less than one hundred percent (100%) of the
Rentable Area of the Building shall be appropriately adjusted to reflect one hundred percent (100%) occupancy of the existing Rentable Area of the Building during such period. In determining Operating Expenses, if any services or utilities are
separately charged to tenants of the Building or others, Operating Expenses shall be adjusted by Landlord to reflect the amount of expense which would have been incurred for such services or utilities on a full time basis for normal Building
operating hours. Operating Expenses for the Tenant’s Base Year for Operating Expenses (as defined in Item 8 of the Basic Lease Provisions) shall not include Operating Expenses attributable to temporary market-wide labor-rate
increases and/or utility rate increases due to extraordinary circumstances, including, but not limited to Force Majeure, conservation surcharges, boycotts, embargoes, or other shortages. In no event shall the components of utilities for any calendar
year related to electrical costs be less than the components of electrical costs in the Base Year for Operating Expenses. In the event (i) the Commencement Date shall be a date other than January 1, (ii) the date fixed for the
expiration of the Lease Term shall be a date other than December 31, (iii) of any early termination of this Lease, or (iv) of any increase or decrease in the size of the Premises, then in each such event, an appropriate adjustment in
the application of this Paragraph 3 shall, subject to the provisions of this Lease, be made to reflect such event on a basis reasonably determined by Landlord to be consistent with the principles underlying the provisions of this Paragraph
3. Landlord shall also have the right, in its sole discretion, to allocate and prorate any portion or portions of the Operating Expenses in any reasonable manner, provided that in all cases the allocation and proration is handled the same way in
the Base Operating Expense and in Base Real Estate Taxes as in subsequent years. Without limiting the generality of the foregoing, Landlord shall have the right, from time to time, to fairly and equitably allocate and prorate on a commercially
reasonable basis some or all of the Operating Expenses among different tenants (the “Cost Pools”), adjusting Tenant’s Proportionate Share as to each of the separately allocated costs based on the ratio of the Rentable Area of
the Premises to the Rentable Area of all of the premises to which such costs are allocated. In placing Tenant in any Cost Pools, Landlord shall not treat Tenant in any unfair, arbitrary or inequitable manner. Such Cost Pools may include, without
limitation, the office space tenants and retail space tenants of the Building. 
 (g) Prior to the commencement of each calendar year of the
Lease Term following the Commencement Date, Landlord shall give to Tenant a written estimate of Tenant’s Proportionate Share of Operating Expenses Excess and/or Taxes Excess, if any, for the Building and/or the Land for the ensuing year. Tenant
shall pay such estimated amount to Landlord in equal monthly installments, in advance on the first day of each month, concurrent with each payment of Base Rent. For the avoidance of doubt, no estimated amounts shall be payable on account of
Tenant’s Proportionate Share of Operating Expenses Excess during the Base Year for Operating Expenses and no estimated amounts shall be payable on account of Tenant’s Proportionate Share of Tax Excess during the Base Year for Real Estate
Taxes. Within one hundred eighty (180) after the end of each calendar year (subject to the first sentence of subparagraph (i), below), Landlord shall 

  
 -13- 

 
furnish Tenant a statement indicating in reasonable detail the excess or shortfall of (i) Operating Expenses over Base Operating Expenses for such period, (ii) Real Estate Taxes over
Base Real Estate Taxes for such period, and the parties shall, within thirty (30) days thereafter, make any payment or allowance necessary to adjust Tenant’s estimated payments to Tenant’s actual share of such excess or shortfall as
indicated by such annual statement. Such statement shall constitute an account stated, subject to the provisions of subparagraph 3(i) below. Any payment due Landlord shall be payable by Tenant within thirty (30) days after written demand
from Landlord. Any amount due Tenant shall be credited against installments next becoming due under this Paragraph 3(g) or refunded to Tenant, if requested by Tenant. The terms and provisions of the foregoing sentences shall survive the
expiration or earlier termination of this Lease. 
 (h) Tenant shall pay when due, all taxes and assessments (i) levied against any
personal property, Alterations, tenant improvements or trade fixtures of Tenant in or about the Premises, (ii) based upon this Lease or any document to which Tenant is a party creating or transferring an interest in this Lease or an estate in
all or any portion of the Premises, and (iii) levied for any business, professional, or occupational license fees. If any such taxes or assessments are levied against Landlord or Landlord’s property or if the assessed value of the Land and
Building is increased by the inclusion therein of a value placed upon such personal property or trade fixtures, Tenant shall within thirty (30) days after written demand by Landlord reimburse Landlord for the taxes and assessments so levied
against Landlord, or such taxes, levies and assessments resulting from such increase in assessed value. To the extent that any such taxes are not separately assessed or billed to Tenant, Tenant shall pay the amount thereof as invoiced to Tenant by
Landlord. 
 (i) Any delay or failure of Landlord in (i) delivering any estimate or statement described in this Paragraph 3, or
(ii) computing or billing Tenant’s Proportionate Share of Operating Expenses Excess and/or Taxes Excess shall not constitute a waiver of its right to require an increase in Additional Rent, or in any way impair the continuing obligations
of Tenant under this Paragraph 3. In the event of any dispute as to any Additional Rent due under this Paragraph 3, Tenant, an officer of Tenant or Tenant’s certified public accountant (but (a) in no event shall Tenant hire
or employ an accounting firm or any other person to audit Landlord as set forth under this Paragraph who is compensated or paid for such audit on a contingency basis and (b) in the event Tenant hires or employs an independent certified public
accountant to perform such audit, Tenant shall provide Landlord with a copy of the engagement letter) shall have the right after reasonable notice and at reasonable times to inspect Landlord’s accounting records at Landlord’s accounting
office. If, after such inspection, Tenant still disputes such Additional Rent, upon Tenant’s written request therefor, a certification as to the proper amount of Operating Expenses and/or Real Estate Taxes and the amount due to or payable by
Tenant shall be made by an independent certified public accountant. If Landlord and Tenant cannot mutually agree to an independent certified public accountant, then the parties agree that Landlord shall choose an independent certified public
accountant to conduct the certification as to the proper amount of Tenant’s Proportionate Share of Operating Expenses and/or Real Estate Taxes due by Tenant for the period in question; provided, however, such certified public accountant shall
not be the accountant who conducted Landlord’s initial calculation of Operating Expenses and/or Real Estate Taxes to which Tenant is now objecting. Such certification shall be final and conclusive as to all parties. The parties shall endeavor
to cause such appointed accountant to render its certification within thirty (30) days. If the certification reflects that Tenant has overpaid Tenant’s Proportionate Share of Operating Expenses and/or Real Estate Taxes for the period in
question, then Landlord 

  
 -14- 

 
shall, at Tenant’s option (i) credit such excess to Tenant’s next payment of Operating Expenses and/or Real Estate Taxes or, (ii) promptly refund such excess to Tenant
Conversely, if Tenant has underpaid Tenant’s Proportionate Share of Operating Expenses and/or Real Estate Taxes, Tenant shall promptly pay such additional Operating Expenses and/or Real Estate Taxes to Landlord. Tenant agrees to pay the cost of
such certification and the investigation with respect thereto unless it is determined that Landlord’s original statement was in error in Landlord’s favor by more than five percent (5%). Tenant waives the right to dispute any matter
relating to the calculation of Operating Expenses and/or Real Estate Taxes or Additional Rent under this Paragraph 3 if any claim or dispute with respect thereto is not asserted in writing to Landlord within sixty (60) days after
delivery to Tenant of the original billing statement with respect thereto. Subject to the terms herein, such statement shall be considered final, except as to matters which are timely disputed and as to any exceptions arising from such disputes
which are not asserted by Tenant within sixty (60) days following Landlord making the appropriate records available for examination as described above. Notwithstanding the foregoing, Tenant shall maintain strict confidentiality of all of
Landlord’s accounting records and shall not disclose the same to any other person or entity except for Tenant’s professional advisory representatives (such as Tenant’s employees, accountants, advisors, attorneys and consultants) with
a need to know such accounting information, who agree to similarly maintain the confidentiality of such financial information. 
 (j) Even
though the Lease Term has expired and Tenant has vacated the Premises, when the final determination is made of Tenant’s Proportionate Share of Operating Expenses Excess and/or Taxes Excess for the year in which this Lease terminates, Tenant
shall pay within thirty (30) days any increase due over the estimated Operating Expenses and/or Real Estate Taxes paid, and conversely, any overpayment made by Tenant shall be promptly refunded to Tenant by Landlord within thirty (30) days
after the determination of such overpayment. This Paragraph 3(i) shall survive the expiration or earlier termination of this Lease. 

(k) The Base Rent, Additional Rent, late fees, and other amounts required to be paid by Tenant to Landlord hereunder (including the Operating
Expenses Excess and Taxes Excess) are sometimes collectively referred to as, and shall constitute, “Rent”. 
 4. IMPROVEMENTS
AND ALTERATIONS 
 (a) Except as set forth in the Work Letter attached hereto as Exhibit B, Landlord shall deliver the
Premises to Tenant, and Tenant agrees to accept the Premises from Landlord in its existing “AS-IS”, “WHERE-IS” and “WITH ALL FAULTS” condition, and Landlord shall have no obligation to refurbish or otherwise improve the
Premises throughout the Lease Term. Landlord represents to Tenant that, as of the Commencement Date, (x) all HVAC, mechanical, electrical, plumbing and life safety Building systems that serve the Premises shall be in good working order,
condition and repair, and (y) the Premises shall be free of Hazardous Materials. Tenant has informed Landlord that Tenant is purchasing from Juniper Pharmaceuticals, Inc. all of the furniture, fixtures, equipment, wiring and cabling, and other
property presently located at the Premises, and Landlord is delivering the Premises to Tenant broom clean with no obligation to remove any furniture, fixtures, equipment, wiring and cabling, and other property from the Premises. Landlord shall use
reasonable care in the performance of Landlord’s Work to avoid damaging such items. 

  
 -15- 

 (b) Any alterations, additions, or improvements made by or on behalf of Tenant to the
Premises (“Alterations”) shall be subject to Landlord’s prior written consent and Alterations may to the extent necessary include installation of equipment and cabling in the Installation Areas. Landlord’s consent shall
not be unreasonably withheld, conditioned or delayed with respect to proposed Alterations that (i) comply with all applicable laws, ordinances, rules and regulations; (ii) are compatible with the Building and its mechanical, electrical,
HVAC and life safety systems; (iii) will not interfere with the use and occupancy of any other portion of the Building by any other tenant or their invitees; (iv) do not affect the structural portions of the Building; and, (v) do not
and will not, whether alone or taken together with other improvements, require the construction of any other improvements or alterations within the Building, (excluding Landlord’s Work). Notwithstanding the foregoing, Alterations which
(x) consist solely of decorative or cosmetic work that does not affect or involve the structural elements or Building systems and (y) which do not cost in excess of Sixty Thousand Dollars ($60,000.00) in the aggregate, at any given time
(either in a single project or a series of related projects) (“Cosmetic Alterations”), shall not be subject to Landlord’s prior approval provided that Tenant delivers a reasonable description of such Alterations to Landlord at
least ten (10) business days prior to commencing such work and subject to the remaining provisions of this Paragraph 4. Tenant shall cause, at its sole cost and expense, all Alterations to comply with insurance requirements and with Laws
and shall construct, at its sole cost and expense, any alteration or modification required by Laws as a result of any Alterations. All Alterations shall be constructed at Tenant’s sole cost and expense, in a first class and good and workmanlike
manner by contractors reasonably acceptable to Landlord and only good grades of materials shall be used. All plans and specifications for any Alterations shall be submitted to Landlord for its approval. Landlord may monitor construction of the
Alterations and Tenant shall reimburse Landlord for any costs incurred by Landlord in monitoring such construction. Without limiting the generality of the foregoing, Tenant shall pay to Landlord, within ten (10) business days after completion
of any Alterations, the actual, reasonable costs incurred by Landlord for services rendered by Landlord’s management personnel and engineers to coordinate and/or supervise any of the Alterations to the extent such services are provided in
excess of or after the normal on-site hours of such engineers and management personnel. Landlord’s right to review plans and specifications and to monitor construction shall be solely for its own benefit, and Landlord shall have no duty to see
that such plans and specifications or construction comply with applicable laws, codes, rules and regulations. Without limiting the other grounds upon which Landlord may refuse to approve any contractor or subcontractor, Landlord may take into
account the desirability of maintaining harmonious labor relations at the Building. Landlord may also require that all life safety related work and all mechanical, electrical, plumbing and roof related work be performed by contractors designated by
Landlord. Landlord shall have the right, in its sole discretion, to instruct Tenant to remove those improvements or Alterations from the Premises and the Installation Areas which (i) were not approved in advance by Landlord, and (ii) were
not built in conformance with the plans and specifications approved by Landlord. In addition, Landlord shall specify during its review of plans and specifications for Alterations those Alterations which Landlord will require Tenant to remove upon
the expiration of this Lease. Except as set forth in the preceding sentence, Tenant shall not be obligated to remove such Alterations at the expiration of this Lease. Landlord shall not unreasonably withhold or delay its approval of improvements or
Alterations that Landlord requires Tenant to remove at the expiration of the Lease, but may require additional security from Tenant with respect thereto. If upon the termination of this Lease Landlord requires Tenant to remove any or all of such
Alterations from 

  
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 the Premises and the Installation Areas, then Tenant, at Tenant’s sole cost and expense, shall promptly
remove such Alterations and improvements and Tenant shall repair and restore the Premises and the Installation Areas to their original condition as of the later of the Commencement Date or the completion of Landlord’s Work, reasonable wear and
tear excepted. Any Alterations remaining in the Premises or the Installation Areas following the expiration of the Lease Term or following the surrender of the Premises from Tenant to Landlord, shall become the property of Landlord unless Landlord
notifies Tenant otherwise. Tenant shall provide Landlord with the identities and mailing addresses of all persons performing work or supplying materials, prior to beginning such construction, and Landlord may post on and about the Premises notices
of non-responsibility pursuant to applicable law. Tenant shall assure payment for the completion of all work free and clear of liens and shall provide certificates of insurance for worker’s compensation and other coverage in amounts and from an
insurance company reasonably satisfactory to Landlord protecting Landlord against liability for bodily injury or property damage during construction. Upon completion of any Alterations and upon Landlord’s reasonable request, Tenant shall
deliver to Landlord sworn statements setting forth the names of all contractors and subcontractors who did work on the Alterations and final lien waivers from all such contractors and subcontractors. Additionally, upon completion of any Alteration
which requires the filing of plans with the designated office of the Commonwealth of Massachusetts or the City of Boston to allow Tenant to lawfully construct such Alterations, Tenant shall provide Landlord, at Tenant’s expense, with a complete
set of plans in reproducible form and specifications reflecting the actual conditions of the Alterations, together with a copy of such plans on diskette in the AutoCAD format or such other format as may then be in common use for computer assisted
design purposes. Tenant shall pay to Landlord, as additional rent, the reasonable costs of Landlord’s engineers and other consultants (but not Landlord’s on-site management personnel) for review of all plans, specifications and working
drawings for the Alterations and for the incorporation of such Alterations in the Landlord’s master Building drawings, within ten (10) business days after Tenant’s receipt of invoices either from Landlord or such consultants together
with (in any event) an administrative charge of five percent (5%) of the actual costs of such work (except that in the case of any Cosmetic Alterations there shall be no such administrative charge). 

(c) Tenant shall keep the Premises, the Building and the Land free from any and all liens arising out of any Alterations, work performed,
materials furnished, or obligations incurred by or for Tenant. In the event that Tenant shall not, within ten (10) business days following written notice from Landlord of the imposition of any such lien, cause the same to be released of record
by payment or posting of a bond in a form and issued by a surety reasonably acceptable to Landlord, Landlord shall have the right, but not the obligation, to cause such lien to be released by such means as it shall deem proper (including payment of
or defense against the claim giving rise to such lien); in such case, Tenant shall reimburse Landlord for all amounts so paid by Landlord in connection therewith, together with all of Landlord’s reasonable third party out of pocket costs and
expenses, with interest thereon at the Default Rate (defined below) and Tenant shall indemnify and defend each and all of the Landlord Indemnitees (defined below) against any damages, losses or costs arising out of any such claim. Tenant’s
indemnification of Landlord contained in this Paragraph shall survive the expiration or earlier termination of this Lease. Such rights of Landlord shall be in addition to all other remedies provided herein or by law. 

  
 -17- 

 (d) NOTICE IS HEREBY GIVEN THAT LANDLORD SHALL NOT BE LIABLE FOR ANY LABOR, SERVICES OR
MATERIALS FURNISHED OR TO BE FURNISHED TO TENANT, OR TO ANYONE HOLDING THE PREMISES THROUGH OR UNDER TENANT, AND THAT NO MECHANICS’ OR OTHER LIENS FOR ANY SUCH LABOR, SERVICES OR MATERIALS SHALL ATTACH TO OR AFFECT THE INTEREST OF LANDLORD IN
THE PREMISES. 
 5. REPAIRS 

(a) Landlord’s obligation with respect to repair as part of Basic Services shall be limited to (i) the structural portions of the
Building, (ii) the exterior walls of the Building, including, without limitation, glass and glazing, (iii) the roof, (iv) HVAC, mechanical, electrical, plumbing and life safety systems except for any lavatory, shower, toilet, wash
basin and kitchen facilities that serve Tenant exclusively and any supplemental heating and air conditioning systems (including all plumbing connected to said facilities or systems up to the point where such plumbing connects with the common
plumbing system) and (v) Common Areas. Landlord shall not be deemed to have breached any obligation with respect to the condition of any part of the Land or Building unless Tenant has given to Landlord written notice of any required repair and
Landlord has not made such repair within a reasonable time following the receipt by Landlord of such notice. The foregoing notwithstanding: (i) Tenant shall pay for the cost of any repairs as a result of damage to any of the foregoing to the
extent caused by the acts or omissions of Tenant or it agents, employees or contractors, except to the extent such repairs are covered by insurance carried or required to be carried by Landlord pursuant to the provisions of Paragraph 8(e)
below; (ii) the obligations of Landlord pertaining to damage or destruction by casualty shall be governed by the provisions of Paragraph 9; and (iii) the obligations of Landlord pertaining to damage or destruction by condemnation
shall be governed by the provisions of Paragraph 10. Landlord shall have the right but not the obligation to undertake work of repair that Tenant is required to perform under this Lease and that Tenant fails or refuses to perform within
applicable periods (including applicable notice and grace periods, if any). All costs reasonably incurred by Landlord (including out of pocket costs and a reasonable allocation of Landlord’s internal costs if employees of Landlord perform such
work or repair) in performing any such work or repair for the account of Tenant shall be repaid by Tenant to Landlord upon demand, together with an administration fee equal to fifteen percent (15%) of such costs. Except as expressly provided in
Paragraph 7(f) and Paragraph 9 of this Lease, there shall be no abatement of Rent and except for the obligation to make repairs necessitated by Landlord’s acts or omissions, no liability of Landlord by reason of any injury to or
interference with Tenant’s business arising from the making of any repairs, alterations or improvements in or to any portion of the Premises, the Building or the Land. Tenant waives the right to make repairs at Landlord’s expense under any
law, statute or ordinance now or hereafter in effect. 
 (b) Tenant, at its expense excepting reasonable wear and tear (i) shall keep
the Premises and all fixtures contained therein in a safe, clean and neat condition, and (ii) shall bear the cost of maintenance and repair, by contractors reasonably acceptable to the Landlord (such approval not to be unreasonably withheld,
conditioned or delayed), of all facilities which are not expressly required to be maintained or repaired by Landlord and which are located in the Premises, including, without limitation, lavatory, shower, toilet, wash basin and kitchen facilities,
and supplemental heating and air conditioning systems (including all plumbing connected to said facilities or systems installed by or on behalf of Tenant or existing in the Premises or in the Installation Areas at the time of Landlord’s
delivery of the Premises to Tenant and serving the Premises). Tenant shall 

  
 -18- 

 
make all repairs to the Premises and the Installation Area not required to be made by Landlord under sub-paragraph (a) above with replacements of any materials to be made by use of
materials of equal or better quality. Tenant shall be responsible for all decorating, remodeling, alteration and painting, if any, that Tenant requires during the Lease Term. Tenant shall pay for the cost of any repairs to the Premises, the Building
or the Land made necessary by any negligence or willful misconduct of Tenant or any of its assignees, subtenants, employees or their respective agents, representatives, contractors, or other persons permitted in or invited to the Premises, the
Building or the Land by Tenant, except to the extent such repairs are covered by insurance carried or required to be carried by Landlord or Tenant pursuant to the provisions of Paragraph 8(e) below. If Tenant fails to make such repairs or
replacements within fifteen (15) days after written notice from Landlord, Landlord may at its option make such repairs or replacements, and Tenant shall within ten (10) days after written demand pay Landlord the cost thereof reasonably
incurred by Landlord (including out of pocket costs and a reasonable allocation of Landlord’s internal costs if employees of Landlord perform such work or repair), together with an administration fee equal to fifteen percent (15%) of such
costs. 
 (c) Upon the expiration or earlier termination of this Lease, Tenant shall surrender the Premises in a safe, clean and neat
condition, normal wear and tear and damage by fire or other casualty excepted. Except as otherwise set forth in Paragraph 4(b) of this Lease, Tenant shall remove from the Premises and the Installation Areas all trade fixtures, furnishings and
other personal property of Tenant and all computer and phone cabling and wiring installed by or on behalf of Tenant, shall repair all damage caused by such removal and shall restore the Premises to its condition as of the later of the Commencement
Date or the completion of Landlord’s Work, reasonable wear and tear excepted. In addition to all other rights Landlord may have, in the event Tenant does not so remove any such fixtures, furnishings or personal property, Tenant shall be deemed
to have abandoned the same, in which case Landlord may store or dispose of the same at Tenant’s expense, appropriate the same for itself, and/or sell the same in its discretion. 

6. USE OF PREMISES 

(a) Tenant shall use the Premises only for general office uses and uses customarily accessory thereto and shall not use the Premises or permit
the Premises to be used for any other purpose. Landlord shall have the right to deny its consent to any change in the permitted use of the Premises in its sole and absolute discretion. 

(b) Tenant shall not at any time use or occupy the Premises, or permit any act or omission in or about the Premises in violation of any
applicable law, statute, ordinance or any governmental rule, regulation or order (collectively, “Law” or “Laws”) and Tenant shall, upon written notice from Landlord, discontinue any use of the Premises which is
declared by any governmental authority to be a violation of Law. If any Law shall, by reason of the nature of Tenant’s use or occupancy of the Premises for other than general office use, impose any duty upon Tenant or Landlord with respect to
(i) modification or other maintenance of the Premises, the Building or the Land, or (ii) the use, Alteration or occupancy thereof, Tenant shall comply with such Law at Tenant’s sole cost and expense. This Lease shall be subject to all
Security Documents (as defined in Paragraph 16(a) below) and all covenants, conditions and restrictions affecting the Premises, the Building or the Land, including, but not limited to, any subordination agreements described in Paragraph
16(a) below, provided that Landlord hereby represents, warrants and covenants that no such Security Documents, covenants, conditions and restrictions adversely affect the use and occupancy of the Premises for general office use, access to the
Premises or the exercise of Tenant’s right to use the parking garage. 
  

  
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 (c) Tenant shall not do or permit to be done anything which may invalidate any insurance
coverage that is in place affording coverage at the location, or that would increase the risk of loss at the location, or that would cause an increase in the cost of any insurance policy covering the Building, the Land and/or property located
therein and Tenant shall comply with all rules, orders, regulations and requirements as set forth in all applicable fire codes and ordinances issued by any federal, state or local governmental body, or by any other organization performing a similar
function and issuing codes that pertain to the location. In addition to all other remedies of Landlord, Landlord may require Tenant, promptly upon written demand, to reimburse Landlord for the full amount of any additional premiums charged for such
policy or policies by reason of Tenant’s failure to comply with the provisions of this Paragraph 6. 
 (d) Tenant shall not in
any way interfere with the rights or quiet enjoyment of other tenants or occupants of the Building. Tenant shall not use or allow the Premises to be used for any unlawful purpose, nor shall Tenant cause, maintain, or permit any nuisance in, on or
about the Premises, the Building or the Land. Tenant shall not place weight upon any portion of the Premises exceeding the structural floor load of 70 pounds per square foot of area or otherwise use any Building system in excess of its capacity or
in any other manner which may damage such system or the Building. Tenant shall not create within the Premises a working environment with a density of greater than the lesser of (i) one (1) person per 150 square feet of Rentable Area, or
(ii) the maximum density permitted by Law. Business machines and mechanical equipment shall be placed and maintained by Tenant, at Tenant’s expense, in locations and in settings sufficient in Landlord’s reasonable judgment to absorb
and prevent vibration, noise and annoyance. Tenant shall not commit or suffer to be committed any waste in, on, upon or about the Premises, the Building or the Land. 

(e) Tenant shall take all reasonable steps necessary to adequately secure the Premises from unlawful intrusion, theft, fire and other hazards,
and shall keep and maintain any and all security devices in or on the Premises in good working order (reasonable wear and tear excepted), including, but not limited to, exterior door locks for the Premises and smoke detectors and burglar alarms
located within the Premises and shall cooperate with Landlord and other tenants in the Building with respect to access control and other safety matters. 

(f) As used herein, the term “Hazardous Material” means any (a) oil or any other petroleum-based substance, flammable
substances, explosives, radioactive materials, hazardous wastes or substances, toxic wastes or substances or any other wastes, materials or pollutants which (i) pose a hazard to the Building or to persons on or about the Land or (ii) cause
the Building or the Land to be in violation of any Laws; (b) asbestos in any form, urea formaldehyde foam insulation, transformers or other equipment that contain dielectric fluid containing levels of polychlorinated biphenyls, or radon
gas; (c) chemical, material or substance defined as or included in the definition of “hazardous substances”, “hazardous wastes”, “hazardous materials”, “extremely hazardous waste”, “restricted
hazardous waste”, or “toxic substances” or words of similar import under any applicable local, state or federal law or under the regulations adopted or publications promulgated pursuant thereto, including, but not limited to, the
Comprehensive 

  
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Environmental Response, Compensation and Liability Act of 1980, as amended, 42 U.S.C. §9601, et seq.; the Hazardous Materials Transportation Act, as amended, 49 U.S.C. §1801, et seq.;
the Federal Water Pollution Control Act, as amended, 33 U.S.C. §1251, et seq.; the Resource Conservation and Recovery Act, as amended, 42 U.S.C. §6901, et seq.; the Safe Drinking Water Act, as amended, 42 U.S.C. §300, et seq.; the
Toxic Substances Control Act, as amended, 15 U.S.C. §2601, et seq.; the Federal Hazardous Substances Control Act, as amended, 15 U.S.C. §1261, et seq.; the Occupational Safety and Health Act, as amended, 29 U.S.C. §651, et seq.; and
Massachusetts General Laws, Chapters 21C and 21E; (d) other chemical, material or substance, exposure to which is prohibited, limited or regulated by any governmental authority or may or could pose a hazard to the health and safety of the
occupants of the Building or the owners and/or occupants of property adjacent to or surrounding the Building, or any other person coming upon the Building or the Land or adjacent property; and (e) other chemicals, materials or substances which
may or could pose a hazard to the environment. The term “Permitted Hazardous Materials” shall mean Hazardous Materials which are contained in ordinary office supplies of a type and in quantities typically used in the ordinary course
of business within executive offices of similar size in the comparable office buildings, but only if and to the extent that such supplies are transported, stored and used in full compliance with all applicable laws, ordinances, orders, rules and
regulations and otherwise in a safe and prudent manner. Hazardous Materials which are contained in ordinary office supplies but which are transported, stored and used in a manner which is not in full compliance with all applicable laws, ordinances,
orders, rules and regulations or which is not in any respect safe and prudent shall not be deemed to be “Permitted Hazardous Materials” for the purposes of this Lease. 

(i) Tenant, its assignees, subtenants, and their respective agents, servants, employees, representatives and contractors (collectively referred
to herein as “Tenant Affiliates”) shall not cause or permit any Hazardous Material to be brought upon, kept or used in or about the Premises by Tenant or by Tenant Affiliates without the prior written consent of Landlord (which may
be granted, conditioned or withheld in the sole discretion of Landlord), save and except only for Permitted Hazardous Materials, which Tenant or Tenant Affiliates may bring, store and use in reasonable quantities for their intended use in the
Premises, but only in full compliance with all applicable laws, ordinances, orders, rules and regulations. On or before the expiration or earlier termination of this Lease, Tenant shall remove from the Premises all Hazardous Materials (including,
without limitation, Permitted Hazardous Materials), regardless of whether such Hazardous Materials are present in concentrations which require removal under applicable laws, except to the extent that such Hazardous Materials were present in the
Premises as of the Commencement Date and were not brought onto the Premises by Tenant or Tenant Affiliates. 
 (ii) Tenant agrees to
indemnify, defend and hold Landlord and its Affiliates (defined below) harmless for, from and against any and all claims, actions, administrative proceedings (including informal proceedings), judgments, damages, punitive damages, penalties, fines,
costs, liabilities, interest or losses, including reasonable attorneys’ fees and expenses, court costs, consultant fees, and expert fees, together with all other costs and expenses of any kind or nature that arise during or after the Lease Term
directly or indirectly from or in connection with the presence or release of any Hazardous Material in or into the air, soil, surface water or groundwater at, on, about, under or within the Premises and/or the Building and/or the Land, or any
portion thereof caused by Tenant or Tenant Affiliates. 

  
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 (iii) In the event any investigation or monitoring of site conditions or any clean-up,
containment, restoration, removal or other remedial work (collectively, the “Remedial Work”) is required under any applicable federal, state or local Law, by any judicial order, or by any governmental entity as the result of
operations or activities upon, or any use or occupancy of any portion of the Premises by Tenant or Tenant Affiliates, Landlord shall perform or cause to be performed the Remedial Work in compliance with such Law or order at Tenant’s sole cost
and expense. All Remedial Work shall be performed by one or more contractors approved by Landlord, and under the supervision of a consulting engineer, selected by Tenant and approved in advance in writing by Landlord (such approval not to be
unreasonably withheld, conditioned or delayed). All costs and expenses of such Remedial Work shall be paid by Tenant, including, without limitation, the charges of such contractor(s), the consulting engineer, and Landlord’s reasonable
attorneys’ fees and costs incurred in connection with monitoring or review of such Remedial Work. 
 (iv) Each of the covenants and
agreements of Tenant set forth in this Paragraph 6(f) shall survive the expiration or earlier termination of this Lease. 
 7.
UTILITIES AND SERVICES 
 (a) During the Lease Term, the Building and the Parking Garage will be operated with
twenty-four hour, seven day per week access, and Tenant shall be entitled to such access, such access to be controlled (but not prohibited) during non-Business Hours, and Landlord shall furnish, or cause to be furnished to the Premises, the
utilities and services described in this Paragraph 7(a) (collectively the “Basic Services”): 
 (i) Tepid or cold
water at those points of supply provided for general use of other tenants in the Building; 
 (ii) During Business Hours, central heat and
air conditioning in season, at such temperatures and in such amounts as are provided by Landlord as standard to other office tenants of the Building or as may be required by applicable laws, ordinances, rules and regulations or by voluntary
conservation programs with which Class A office buildings in the downtown financial district of Boston are complying, but Landlord shall not be responsible for (A) inadequate air-conditioning or ventilation to the extent the same occurs
because Tenant’s use of power exceeds 6.0 watts per rentable square foot without Tenant providing adequate supplementary air-conditioning and ventilation therefor or (B) if the number of individuals in the Premises exceeds one (1) per
one hundred fifty (150) rentable square feet or (C) by reason of any non-standard office use which requires supplemental air-conditioning and/or ventilation; 

(iii) Maintenance, repairs, structural and exterior maintenance (including, without limitation, exterior glass and glazing), painting and
electric lighting service for all Common Areas comparable to other first class office buildings in the financial district of Boston, subject to the limitation contained in Paragraph 5(a) above; 

(iv) Janitorial service on a five (5) day week basis (Monday through Friday); 

  
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 (v) An electrical system to convey power delivered by public utility providers selected by
Landlord in amounts sufficient for normal office operations as provided in similar office buildings, but not to exceed a total allowance of 6.0 watts per square foot of Rentable Area during normal office hours (which includes an allowance for
lighting of the Premises at the maximum wattage per square foot of Rentable Area permitted under applicable laws, ordinances, orders, rules and regulations), provided that no single item of electrical equipment requires a voltage other than 120
volts, single phase; and 
 (vi) Public elevator service and a freight elevator serving the floors on which the Premises are situated, during
Business Hours. Subject to Force Majeure, reduced service, consisting of at least two automatic or manually operated elevators accessing the Premises from the lobby area, will be provided at all other times. Freight elevator service shall be
available in common with other tenants from 7:00 A.M. to 6:00 P.M. daily (Saturdays, Sundays and Holidays excepted), with a thirty (30) minute time limit for deliveries, and at other times with longer time limits at reasonable charges and only
by arrangement in advance with Building management. 
 Notwithstanding the fact that electrical service is to be provided as described under
Paragraph 7(a)(v), electric service shall be separately metered, and Tenant shall pay the amounts charged therefor by the utility provider directly to the utility provider on or before the due dates therefor. 

(b) During the Lease Term, Landlord shall provide to Tenant at Tenant’s sole cost and expense (and subject to the limitations hereinafter
set forth) the following extra services (collectively the “Extra Services”): 
 (i) Such extra cleaning and janitorial
services requested by Tenant, and agreed to by Landlord, for special improvements or Alterations; 
 (ii) Subject to Paragraph 7(d)
below, additional heating, air conditioning and ventilating capacity in excess of that typically provided by the Building; 
 (iii)
Maintaining and replacing lamps, bulbs, and ballasts; 
 (iv) If Tenant desires Building standard HVAC service to be provided to the Premises
during hours other than Business Hours, Tenant may request such service in accordance with procedures from time to time established by Landlord. Subject to system capacity and the requirements of others in the Building, Landlord will furnish such
after-hours HVAC service to the Premises. Where Tenant requests such service, Tenant shall pay its prorated share of the charge of $150.00 per hour per full floor (as such charge shall vary from time to time as generally applied to other office
tenants in the Building) for the costs of operating the air handling units on the floor on account of such after-hours HVAC service, but otherwise shall not be required to pay a separate hourly charge for such after-hours HVAC service under this
Paragraph 7(b); 
 (v) If Tenant requires supplemental air-conditioning, in excess of the Building standard HVAC service, for business
machines, computer rooms, meeting rooms or other purposes, or because of occupancy or unusual electrical loads, supplemental HVAC equipment may be installed pursuant to Paragraph 4(b) above and shall be operated and maintained by Tenant at
its sole cost, but only to the extent that the same is compatible with the Building mechanical systems. In addition to paying costs for operating such supplemental HVAC equipment under Paragraph 7(b)(iv) above, Tenant may use, to the extent
available, Building condenser water and shall pay additional rent at the rate of $300.00 per ton, per annum, for the use of such condenser water for such supplemental HVAC equipment (such amount subject to increase from time to time); and 

  
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 (vi) Any Basic Service in amounts reasonably determined by Landlord to exceed the amounts
required to be provided above, but only if Landlord elects to provide such additional or excess service. Tenant shall pay Landlord the cost of providing such additional services (or an amount equal to Landlord’s reasonable estimate of such
cost, if the actual cost is not readily ascertainable) together, except as to electrical utility charges, with an administration fee equal to fifteen percent (15%) of such cost, within thirty (30) days following presentation of an invoice
therefor by Landlord to Tenant; provided, however, to the extent such additional services are provided directly by Landlord, the administrative fee shall be ten percent (10%) and to the extent such services are provided by third parties,
Landlord will at Tenant’s request provide Tenant with a list of acceptable contractors and if Tenant engages such contractor directly to provide such service (otherwise in accordance with this Lease), Landlord shall charge no administrative
fee. The cost and fee chargeable to Tenant for all extra services shall constitute Rent. 
 (c) Tenant agrees to cooperate fully at all times
with Landlord and to comply with all nondiscriminatory regulations and requirements which Landlord may from time to time reasonably prescribe for the use of the utilities and Basic Services and Extra Services described herein. Landlord shall not be
liable to Tenant for the failure of any other tenant, or its assignees, subtenants, employees, or their respective invitees, licensees, agents or other representatives to comply with such regulations and requirements. The term “Business
Hours” shall be deemed to be Monday through Friday from 8:00 A.M. to 6:00 P.M. and Saturday from 8:00 A.M. to 1:00 P.M., excepting Holidays. The term “Holidays” shall mean all federally observed holidays, including New
Year’s Day, President’s Day, Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day, and to the extent of utilities or services provided by union members engaged at the Property, such other holidays observed by such
unions. 
 (d) If Tenant requires utilities or services in quantities greater than or at times other than that generally furnished by
Landlord as Basic Services as set forth above and Landlord is able to provide the same, Tenant shall pay to Landlord, within fifteen (15) days of receipt of a written statement therefor, Landlord’s charge for such use. In the event that
Tenant shall require additional electric current, water or gas for use in the Premises and if, in Landlord’s reasonable judgment, such excess requirements cannot be furnished unless additional risers, conduits, feeders, switchboards and/or
appurtenances are installed in the Building and such installation is feasible, subject to the conditions stated below, Landlord shall proceed to install the same at the sole cost of Tenant, payable prior to Landlord’s commencing such work. The
installation of such facilities shall be conditioned upon Landlord’s consent (which shall not be unreasonably withheld, conditioned or delayed), and a determination that the installation and use thereof (i) shall be permitted by applicable
Law and insurance regulations, (ii) shall not cause permanent damage or injury to the Building or adversely affect the value of the Building or the Land, and (iii) shall not cause or create a dangerous or hazardous condition or interfere
with or disturb other tenants in the Building. In the case of any additional utilities or services to be provided hereunder, Landlord may require a switch and metering system to be installed so as to measure the amount of such additional utilities
or services. The cost of installation, maintenance and repair thereof shall be paid by Tenant upon demand. Notwithstanding the foregoing, Landlord shall have the right to contract with any utility provider it deems appropriate to provide utilities
to the Building. 

  
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 (e) Landlord shall not be liable for, and Tenant shall not be entitled to, any damages,
abatement or reduction of Rent, or other liability by reason of any failure to furnish any services or utilities described herein for any reason, including, without limitation, when caused by accident, breakage, water leakage, flooding, repairs,
Alterations or other improvements to the Building or the Land, strikes, lockouts or other labor disturbances or labor disputes of any character, governmental regulation, moratorium or other governmental action, inability to obtain electricity, water
or fuel, or any other cause beyond Landlord’s control. Landlord shall be entitled to cooperate with the energy conservation efforts of governmental agencies or utility suppliers and to adjust services or utilities so as to cooperate or comply
with such efforts without being liable for any abatement. No such failure, stoppage, adjustment or interruption of any such utility or service shall be construed as an eviction of Tenant, nor shall the same relieve Tenant from any obligation to
perform any covenant or agreement under this Lease unless Tenant is not able to perform such covenant or agreement as a result of such failure, stoppage, adjustment or interruption. In the event of any failure, stoppage or interruption thereof,
Landlord shall use reasonable efforts to attempt to restore all services promptly. No representation is made by Landlord with respect to the adequacy or fitness of the Building’s ventilating, air conditioning or other systems to maintain
temperatures as may be required for the operation of any computer, data processing or other special equipment of Tenant. 
 (f)
Notwithstanding anything contained in this Lease to the contrary, if (i) an interruption or curtailment, suspension or stoppage of an Essential Service (as said term is hereinafter defined) shall occur as a result of the negligence or willful
misconduct of Landlord, its agents, contractors, or employees or the failure by Landlord to perform its maintenance and repair obligations hereunder, except any of the same due to any act or neglect of Tenant or Tenant’s agents employees,
contractors or invitees or any person claiming by, through or under Tenant (any such repair, negligence, or willful misconduct, or interruption of an Essential Service being hereinafter referred to as a “Service Interruption”), and
(ii) such Service Interruption continues for more than five (5) consecutive business days after Landlord shall have received notice thereof from Tenant, and (iii) as a result of such Service Interruption, the conduct of Tenant’s
normal operations in the Premises are materially and adversely affected, then there shall be an abatement of one day’s Base Rent, Operating Expenses Excess and Taxes Excess for each day during which such Service Interruption continues after
such five (5) business day period; provided, however, if the entire Premises have not been rendered unusable by the Service Interruption, the amount of abatement shall be equitably prorated. The rights granted to Tenant under this paragraph
shall be Tenant’s sole and exclusive remedy resulting from a failure of Landlord to provide Essential Services, and Landlord shall not otherwise be liable for any loss or damage suffered or sustained by Tenant resulting from any failure or
cessation of Essential Services. For purposes hereof, the term “Essential Services” shall mean the following services: access to the Premises, water and sewer/septic service and electricity, air conditioning and heating, but only to
the extent that Landlord has an obligation to provide same to Tenant under this Lease. Any abatement of Base Rent, Operating Expenses Excess and Taxes Excess under this paragraph shall apply only with respect to Base Rent, Operating Expenses Excess
and Taxes Excess allocable to the period after each of the conditions set forth in subsections (i) through (iii) hereof shall have been satisfied and only during such times as each of such conditions shall exist. 

  
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 (g) Landlord reserves the right from time to time to make reasonable and nondiscriminatory
modifications to the above standards for Basic Services and Extra Services provided that such modifications do not decrease or diminish the amount of electrical, heating or cooling or any other Basic Service or Extra Service below the levels that
Landlord is required to provide pursuant to the provisions of this Lease and provided that the HVAC Service shall not be decreased below the Building standard service provided as of the date of this Lease. 

8. INSURANCE 
 (a) Except to the
extent caused by Landlord’s negligence or willful misconduct, or as otherwise specifically provided in this Lease, including but not limited to, Paragraph 8(f) below, Landlord shall not be liable for any injury, loss or damage suffered
by Tenant or to any person or property occurring or incurred in or about the Premises, the Building or the Land from any cause. Without limiting the foregoing, neither Landlord nor any of its partners, officers, trustees, affiliates, directors,
employees, contractors, agents or representatives (collectively, “Affiliates”) shall be liable for and there shall be no abatement of Rent (except in the event of a casualty loss or a condemnation as set forth in Paragraph 9
and Paragraph 10 of this Lease) for (i) any damage to Tenant’s property, (ii) loss of or damage to any property by theft or any other wrongful or illegal act by third parties, or (iii) any injury or damage to persons or
property resulting from fire, explosion, falling plaster, steam, gas, electricity, water or rain which may leak from any part of the Building or from the pipes, appliances, appurtenances or plumbing works therein or from the roof, street or
sub-surface or from any other place or resulting from dampness or any other cause whatsoever or from the acts or omissions of other tenants, occupants or other visitors to the Building or from any other cause whatsoever (other than Landlord’s
sole negligence or willful misconduct), (iv) any diminution or shutting off of light, air or view by any structure which may be erected on lands adjacent to the Building, or (v) any latent or other defect in the Premises or the Building.
Tenant shall give prompt notice to Landlord in the event of (i) the occurrence of a fire or accident in the Premises or in the Building, or (ii) the discovery of a defect therein or in the fixtures or equipment thereof. 

Landlord agrees to indemnify, protect, defend and hold harmless Tenant and its Affiliates for, for, from and against any and all liabilities,
claims, fines, penalties, costs, damages or injuries to persons, damages to property, losses, liens, causes of action, suits, judgments and expenses (including court costs, attorneys’ fees, expert witness fees and costs of investigation) of any
nature, kind or description, arising from injury or death to any person or damage to any property caused by the negligence or willful misconduct of Landlord. 

This Paragraph 8(a) shall survive the expiration or earlier termination of this Lease. 

(b) Tenant hereby agrees to indemnify, protect, defend and hold harmless Landlord and its designated property management company, and their
respective partners, members, affiliates and subsidiaries, and all of their respective officers, trustees, directors, shareholders, employees, servants, partners, representatives, insurers and agents (collectively, “Landlord
Indemnitees”) for, from and against all liabilities, claims, fines, penalties, costs, damages or injuries to persons, damages to property, losses, liens, causes of action, suits, judgments and expenses (including court costs, reasonable
attorneys’ fees, expert witness fees and costs of investigation), of any nature, kind or description of any person or entity, directly or indirectly arising out of, caused by, or 

  
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resulting from (in whole or part) (1) Tenant’s construction of, or use, occupancy or enjoyment of, the Premises, (2) any activity, work or other things done, permitted or suffered
by Tenant and its agents and employees in or about the Premises, (3) any breach or default in the performance of any of Tenant’s obligations under this Lease, (4) any act, omission, negligence or willful misconduct of Tenant or any of
its agents, contractors, employees, business invitees or licensees occurring on or about the Premises, Building, or Land or otherwise arising from the use of the Premises, Building or Land by Tenant or any of its agents, contractors, employees,
business invitees or licensees, or (5) any damage to Tenant’s property, or the property of Tenant’s agents, employees, contractors, business invitees or licensees, located in or about the Premises (collectively,
“Liabilities”), in all cases except to the extent of the negligence or willful misconduct of Landlord or Landlord’s Indemnitees. This Paragraph 8(b) shall survive the expiration or earlier termination of this Lease. 

(c) The respective rights and obligations of Landlord and Tenant under Paragraphs 8(a) and 8(b) shall be subject in all respects
to the applicable terms and provisions of Paragraph 8(f) below. 
 (d) Tenant shall promptly advise Landlord in writing of any action,
administrative or legal proceeding or investigation as to which this indemnification may apply of which Tenant has actual knowledge, and Tenant, at Tenant’s expense, shall assume on behalf of each and every Landlord Indemnitee and conduct with
due diligence and in good faith the defense thereof with counsel reasonably satisfactory to Landlord; provided, however, that any Landlord Indemnitee shall have the right, at its option, to be represented therein by advisory counsel of its own
selection and at its own expense. In the event of failure by Tenant to fully perform in accordance with this Paragraph, Landlord, at its option, and without relieving Tenant of its obligations hereunder, may so perform, but all reasonable costs and
expenses so incurred by Landlord in that event shall be reimbursed by Tenant to Landlord, together with interest on the same from the date any such expense was paid by Landlord until reimbursed by Tenant, at the rate of interest provided to be paid
on judgments, by the law of the jurisdiction to which the interpretation of this Lease is subject. The indemnification provided in Paragraph 8(b) shall not be limited to damages, compensation or benefits payable under insurance policies,
workers’ compensation acts, disability benefit acts or other employees’ benefit acts. 
 (e) Insurance. 

(i) Tenant at all times during the Lease Term shall, at its own expense, keep in full force and effect (A) commercial general liability
insurance in or not materially different than the standard current ISO form affording coverage against bodily injury and property damage with a primary limit of at least $1,000,000 per occurrence, which shall include provision for contractual
liability coverage insuring this Lease as a covered contract and Excess coverage afforded pursuant to an Umbrella form with a per occurrence limit of at least $5,000,000, (B) worker’s compensation insurance to the statutory limit, if any,
and employer’s liability insurance to the limit of $500,000 per occurrence, (C) property coverage written on a Special or other substantially similar ISO form insuring against all risks of direct physical loss or damage to covered property
subject only to standard exclusions and limitation, and not excluding coverage for loss resultant from sprinkler leakage (including sprinkler leakage), vandalism, malicious mischief, and wind and/or hurricane and providing for full replacement cost
without deduction for depreciation if replaced of all of 

  
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Tenant’s personal property, trade fixtures and improvements in the Premises, and (D) business interruption insurance insuring interruption or stoppage of Tenant’s business at the
Premises for a period of not less than twelve (12) months. Landlord and its designated property management firm, Landlord’s mortgagees and all other persons designated by Landlord shall be included as an additional insured on each of said
liability policies (excluding the worker’s compensation policy and the property policy) and said policies shall be issued by an insurance company or companies authorized to do business in the State and which have policyholder ratings not lower
than “A-” and financial ratings not lower than “VII” in Best’s Insurance Guide (latest edition in effect as of the Commencement Date and subsequently in effect as of the date of renewal of the required policies). EACH
PROPERTY INSURANCE POLICY SHALL ALSO INCLUDE AN ENDORSEMENT PROVIDING THAT LANDLORD SHALL RECEIVE THIRTY (30) DAYS PRIOR WRITTEN NOTICE OF ANY CANCELLATION OF, OR NONRENEWAL OF SAID POLICIES. Tenant hereby waives its right of recovery against
any Landlord Indemnitee of any amounts paid by Tenant or on Tenant’s behalf to satisfy applicable worker’s compensation laws. The policies or duly executed certificates showing the material terms for the same, together with satisfactory
evidence of the payment of the premiums therefor, shall be deposited with Landlord not later than the date Tenant first occupies the Premises and upon renewals of such policies prior to the expiration of the term of such coverage. If certificates
are supplied rather than the policies themselves, Tenant shall allow Landlord, at all reasonable times, to inspect the policies of insurance required herein. 

(ii) It is expressly understood and agreed that the coverages required represent Landlord’s minimum requirements and such are not to be
construed to void or limit Tenant’s obligations contained in this Lease, including without limitation Tenant’s indemnity obligations hereunder. Neither shall (A) the insolvency, bankruptcy or failure of any insurance company carrying
Tenant, (B) the failure of any insurance company to pay claims occurring nor (C) any exclusion from or insufficiency of coverage be held to affect, negate or waive any of Tenant’s indemnity obligations under this Paragraph 8
and Paragraph 6(f)(ii) or any other provision of this Lease. With respect to insurance coverages, except worker’s compensation, maintained hereunder by Tenant and insurance coverages separately obtained by Landlord, all insurance
coverages afforded by policies of insurance maintained by Tenant shall be primary insurance as such coverages apply to Landlord, and such insurance coverages separately maintained by Landlord shall be excess, and Tenant shall have its insurance
policies so endorsed. The amount of liability insurance under insurance policies maintained by Tenant shall not be reduced by the existence of insurance coverage under policies separately maintained by Landlord. Tenant shall be solely responsible
for any premiums, assessments, penalties, deductible assumptions, retentions, audits, retrospective adjustments or any other kind of payment due under its policies. Tenant shall increase the amounts of insurance or the insurance coverages as
Landlord may reasonably request from time to time, but not in excess of the requirements of prudent landlords or lenders for similar tenants occupying similar premises in the Boston financial district. 

(iii) Tenant’s occupancy of the Premises without having delivered the required certificates of insurance shall not constitute a waiver of
Tenant’s obligations to provide the required coverages. If Tenant provides to Landlord a certificate that does not evidence the coverages required herein, or that is faulty in any respect, Landlord’s acceptance of such certificate such
shall not constitute a waiver of Tenant’s obligations to provide the proper insurance or the proper certificate evidencing the required coverage. 

  
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 (iv) Throughout the Lease Term, Landlord agrees to maintain (i) fire and extended
coverage insurance, and, at Landlord’s option, earthquake damage coverage, terrorism coverage, wind and hurricane coverage, and such additional property insurance coverage as Landlord deems appropriate, on the insurable portions of the Building
and the Land, for full replacement costs, subject to reasonable deductibles, (ii) boiler and machinery insurance amounts and with deductibles that would be considered standard for a Class A office building in the Boston financial district,
and (iii) commercial general liability insurance. The premiums for any such insurance shall be a part of Operating Expenses. 
 (f)
Mutual Waivers of Recovery. Notwithstanding anything in this Lease to the contrary, Landlord, Tenant, and all parties claiming under them, each mutually release and discharge each other from responsibility for that portion of any loss or
damage paid or reimbursed by an insurer of Landlord or Tenant under any fire, extended coverage or other property insurance policy maintained by Tenant with respect to its obligations under this Lease or by Landlord with respect to its obligations
under this Lease (or which would have been paid had the insurance required to be maintained by such party under this Lease been in full force and effect), no matter how caused, including negligence, and each waives any right of recovery from the
other including, but not limited to, claims for contribution or indemnity, which might otherwise exist on account thereof. Any fire, extended coverage or property insurance policy maintained by Tenant with respect to the Premises, or Landlord with
respect to the Building or the Land, shall contain, in the case of Tenant’s policies, a waiver of subrogation provision or endorsement in favor of Landlord, and in the case of Landlord’s policies, a waiver of subrogation provision or
endorsement in favor of Tenant. Each party agrees to indemnify, protect, defend and hold harmless the other and each of such party’s Affiliates from and against any claim, suit or cause of action asserted or brought by the indemnifying
party’s insurers for, on behalf of, or in the name of the indemnifying party, including, but not limited to, claims for contribution, indemnity or subrogation, brought in contravention of this Paragraph 8(f). The mutual releases,
discharges and waivers contained in this provision shall apply EVEN IF THE LOSS OR DAMAGE TO WHICH THIS PROVISION APPLIES IS CAUSED SOLELY OR IN PART BY THE NEGLIGENCE OF LANDLORD OR TENANT. 

(g) Business Interruption. Landlord shall not be responsible for, and Tenant releases and discharges Landlord from, and Tenant further
waives any right of recovery from Landlord for, any loss for or from business interruption or loss of use of the Premises suffered by Tenant in connection with Tenant’s use or occupancy of the Premises, EVEN IF SUCH LOSS IS CAUSED SOLELY OR IN
PART BY THE NEGLIGENCE OF LANDLORD. 
 (h) Adjustment of Claims. Tenant shall cooperate with Landlord and Landlord’s insurers in
the adjustment of any insurance claim pertaining to the Building or the Land or Landlord’s use thereof. 
 (i) Intentionally
Omitted. 
 (j) Failure to Maintain Insurance. Any failure of Tenant to obtain and maintain the insurance policies and coverages
required hereunder or failure by Tenant to meet any of the insurance requirements of this Lease shall constitute an Event of Default hereunder, and such failure shall entitle Landlord to pursue, exercise or obtain any of the remedies provided for in

  
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Paragraph 12(b), and Tenant shall be solely responsible for any loss suffered by Landlord as a result of such failure. In the event of failure by Tenant to maintain the insurance policies and
coverages required by this Lease or to meet any of the insurance requirements of this Lease, Landlord, at its option, and without relieving Tenant of its obligations hereunder, may obtain said insurance policies and coverages or perform any other
insurance obligation of Tenant, but all costs and expenses incurred by Landlord in obtaining such insurance or performing Tenant’s insurance obligations shall be reimbursed by Tenant to Landlord, together with interest on same from the date any
such cost or expense was paid by Landlord until reimbursed by Tenant, at the Default Rate. 
 9. FIRE OR CASUALTY 

(a) Subject to the provisions of this Paragraph 9, in the event the Premises, or access thereto, is wholly or partially destroyed by
fire or other casualty, Landlord shall (to the extent permitted by Law and covenants, conditions and restrictions then applicable to the Building or the Land) rebuild, repair or restore the Premises and access thereto to substantially the same
condition as existing immediately prior to such destruction (excluding Tenant’s Alterations, trade fixtures, equipment and personal property, which Tenant shall be required to restore) and this Lease shall continue in full force and effect.
Notwithstanding the foregoing, (i) Landlord’s obligation to rebuild, repair or restore the Premises shall not apply to any personal property, above-standard tenant improvements or other items installed or contained in the Premises, and
(ii) Landlord shall have no obligation whatsoever to rebuild, repair or restore the Premises with respect to any damage or destruction occurring during the last twelve (12) months of the term of this Lease or any extension of the term.

 (b) Landlord may elect to terminate this Lease in any of the following cases of damage or destruction to the Premises or the Building:
(i) where the cost of rebuilding, repairing and restoring (collectively, “Restoration”) of the Building, would, regardless of the lack of damage to the Premises or access thereto, in the reasonable opinion of Landlord, exceed
twenty percent (20%) of the then replacement cost of the Building; (ii) in the case of any damage or destruction to any portion of the Building or the Premises by uninsured casualty (except in the event the uninsured casualty was required
to have been insured by Landlord under Paragraph 8(e)(iv) above); or (iii) if Landlord has not obtained appropriate zoning approvals for reconstruction of the Building or Premises. Notice of any such termination shall be given to Tenant
within one hundred twenty (120) days of the date of such damage or destruction and shall be effective thirty (30) days following the date of such notice. If this Lease is not terminated by Landlord and as the result of any damage
or destruction, the Premises, or a portion thereof, are rendered untenantable, the Base Rent shall abate reasonably beginning on the date of damage and continuing through the period of Restoration (based upon the extent to which such damage and
Restoration materially interfere with Tenant’s business in the Premises). This Lease shall be considered an express agreement governing any case of damage to or destruction of the Premises or the Building. This Lease sets forth the terms and
conditions upon which this Lease may terminate in the event of any damage or destruction. 

  
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 (c) Tenant may elect to terminate this Lease by notice to Landlord as hereinafter set forth
(time being of the essence) where substantial completion of Restoration of the Premises or of the access thereto would, in Landlord’s reasonable judgment, take longer than two hundred seventy (270) days from the date of such damage or
destruction or if Landlord, having determined that Restoration would occur in such period, is unable to effect substantial completion of Restoration within such period. Landlord shall, within thirty (30) days of any damage or destruction that
would give Tenant the right to terminate this Lease if the Restoration is not substantially completed within the said 270-day period, notify Tenant of Landlord’s reasonable estimate of the time necessary to effect substantial completion of
Restoration. If the period for substantial completion of Restoration is longer than such 270-day period, Tenant may within thirty (30) days after receipt of Landlord’s notice, terminate this Lease by notice to the Landlord, such
termination to take effect on the date of such notice. If Tenant does not so terminate the Lease even though the period for substantial completion of Restoration is longer than 270 days, this Lease shall continue in full force or effect (unless
terminated by Landlord pursuant to any right it has to terminate), but if Restoration of the Premises or access thereto is not substantially completed by the end of such 270 day period, Tenant shall have the right within thirty (30) days
following the end of such 270 day period to terminate this Lease by notice to the Landlord as of the date of such notice. 
 (d) If this
Lease is not terminated by either Landlord or Tenant and as the result of any damage or destruction, the Premises, or a portion thereof, are rendered untenantable, and in any event during the period the Premises remain subject to this Lease and are
untenantable, the Base Rent shall abate reasonably during the period of Restoration (based upon the extent to which such damage and Restoration materially interfere with Tenant’s business in the Premises). This Lease shall be considered an
express agreement governing any case of damage to or destruction of the Building. This Lease sets forth the terms and conditions upon which this Lease may terminate in the event of any damage or destruction. 

10. EMINENT DOMAIN. In the event the whole of the Premises, the Building or the Land shall be taken under the power of eminent domain, or sold
to prevent the exercise thereof (collectively, a “Taking”), this Lease shall automatically terminate as of the date of such Taking. In the event a Taking of a portion of the Land, the Building or the Premises shall, in the
reasonable opinion of Landlord, substantially interfere with Landlord’s operation thereof, Landlord may terminate this Lease upon thirty (30) days’ written notice to Tenant given at any time within sixty (60) days following the
date of such Taking. In the event that a Taking of a portion of the Premises shall substantially interfere with Tenant’s use and occupancy of the Premises, Tenant may terminate upon thirty (30) days’ written notice to Landlord given
at any time within sixty (60) days following the date of such Taking. For purposes of this Lease, the date of Taking shall be the earlier of the date of transfer of title resulting from such Taking or the date of transfer of possession
resulting from such Taking. In the event that a portion of the Premises is so taken and this Lease is not terminated, Landlord shall, to the extent of proceeds paid to Landlord as a result of the Taking, with reasonable diligence, use commercially
reasonable efforts to proceed to restore (to the extent permitted by Law and covenants, conditions and restrictions then applicable to the Building and/or the Land) the Premises (other than Tenant’s personal property and fixtures, and
above-standard tenant improvements) to a complete, functioning unit. In such case, the Base Rent shall be reduced proportionately based on the portion of the Premises so taken. If all or any portion of the Premises is the subject of a temporary
Taking, this Lease shall remain in full force and effect and Tenant shall continue to perform each of its obligations under this Lease; in such case, Tenant shall be entitled to receive the entire award allocable to the temporary Taking of the
Premises. Except as provided herein, Tenant shall not assert any claim against Landlord or the condemning 

  
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authority for, and hereby assigns to Landlord, any compensation in connection with any such Taking, and Landlord shall be entitled to receive the entire amount of any award therefor, without
deduction for any estate or interest of Tenant. Nothing contained in this Paragraph 10 shall be deemed to give Landlord any interest in, or prevent Tenant from seeking any award against the condemning authority for the Taking of personal
property, fixtures, above standard tenant improvements of Tenant or for relocation or moving expenses recoverable by Tenant from the condemning authority provided that such claim does not reduce award to Landlord. 

11. ASSIGNMENT AND SUBLETTING. 

(a) Except for a Permitted Transfer (as defined in Paragraph 1 l(k) below), Tenant shall not directly or indirectly, voluntarily or
involuntarily, by operation of law or otherwise, assign, sublet, mortgage or otherwise encumber all or any portion of its interest in this Lease or in the Premises or grant any license for any person other than Tenant or its employees to use or
occupy the Premises or any part thereof without obtaining the prior written consent of Landlord, which, if Landlord does not elect to exercise its termination right pursuant to Paragraph 11(c) below, shall not be unreasonably withheld,
conditioned, or delayed. Any such attempted assignment, subletting, license, mortgage, other encumbrance or other use or occupancy without the prior written consent of Landlord shall, at Landlord’s option, be null and void and of no effect. Any
mortgage, or encumbrance of all or any portion of Tenant’s interest in this Lease or in the Premises and any grant of a license for any person other than Tenant or its employees to use or occupy the Premises or any part thereof shall be deemed
to be an “assignment”. In addition, as used in this Paragraph 11, the term “Tenant” shall also mean any entity that has guaranteed Tenant’s obligations under this Lease, and the restrictions applicable to Tenant
contained herein shall also be applicable to such guarantor. 
 (b) No assignment or subletting shall relieve Tenant of its obligation to pay
the Rent and to perform all of the other obligations to be performed by Tenant hereunder. The acceptance of Rent by Landlord from any other person shall not be deemed to be a waiver by Landlord of any provision of this Lease or deemed to be consent
to any subletting or assignment. Consent by Landlord to one subletting or assignment shall not be deemed to constitute consent to any other or subsequent attempted subletting or assignment. If Tenant desires at any time to assign this Lease or to
sublet the Premises or any portion thereof, it shall first notify Landlord of its desire to do so and shall submit in writing to Landlord all pertinent information relating to the proposed assignee or sublessee, all pertinent information relating to
the proposed assignment or sublease, and all such financial information as Landlord may reasonably request concerning the Tenant and proposed assignee or subtenant. Without limiting the generality of the foregoing, the notice to Landlord shall
include: (a) the proposed effective date (which shall not be less than thirty (30) nor more than one hundred and twenty (120) days after Tenant’s notice), (b) the portion of the Premises to be sublet or subject to the
assignment, 
 (c) the terms of the proposed assignment or sublet and the consideration therefor, the name and address of the proposed
transferee, and a copy of all documentation pertaining to the proposed assignment or sublet, (d) current financial statements of the proposed transferee certified by an officer, partner or owner thereof, and any other information reasonably
necessary to enable Landlord to determine the financial responsibility, character, and reputation of the proposed transferee, nature of such transferee’s business and proposed use of the space to be sublet or subject

  
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to the assignment. If requested by Tenant for such proposed transferee, Landlord will execute and deliver a commercially reasonable non-disclosure agreement with respect to such financial
statements or other confidential information that may be provided to Landlord under this Paragraph 11(b); the form of non-disclosure form attached hereto as Exhibit E shall be deemed to be commercially reasonable. 

Any sublease and any assignment shall be in a form and contain conditions reasonably acceptable to Landlord and shall be expressly subject to
the terms and conditions of this Lease, except as the Landlord shall otherwise specifically agree in writing. Any assignment or sublet made without complying with this Paragraph 11 shall, at Landlord’s option, be null, void and of no
effect, or shall constitute a default under this Lease. Any sublease hereunder shall be subordinate and subject to the provisions of this Lease, and if this Lease shall be terminated during the term of any sublease or an assignment of space other
than an assignment of the entire Lease, Landlord shall have the right to: (i) treat such sublease or such assignment as cancelled and repossess the space subject to such sublease or assignment by any lawful means, or (ii) require that such
subtenant or assignee to attorn to and recognize Landlord as its landlord under any such sublease or assignment. If Tenant shall be in default of its obligations under this Lease beyond any applicable notice and cure period, such sublessee or
assignee is hereby directed to make all payments under or in connection with the sublease or assignment directly to Landlord (which Landlord shall apply towards Tenant’s obligations under this Lease) and such sublessee or assignee may rely upon
a statement from Landlord that such payments are to be made to Landlord. 
 (d) At any time within twenty (20) days after
Landlord’s receipt of the information specified in Paragraph 11(b) above, Landlord may by written notice to Tenant elect to terminate this Lease as to the portion of the Premises (or all of the Premises if Tenant proposes to assign this
Lease or to sublease all of the Premises) so proposed to be subleased or assigned, with a proportionate abatement, if the termination relates to only a part of the Premises, in the Rent payable hereunder, provided, however, that such termination
right shall not apply in the case of a Permitted Transfer. If Landlord so terminates the Lease, then Tenant may, by written notice to Landlord given within five (5) days following the delivery of such termination notice from Landlord, rescind
its request for the assignment or sublease and, in such event, Landlord’s termination notice shall be null and void. 
 (e) Tenant
acknowledges that it shall be reasonable for Landlord to withhold its consent to a proposed assignment or sublease in any of the following instances: 

(i) The assignee or sublessee (or any affiliate of the assignee or sublessee) is not, in Landlord’s reasonable opinion, sufficiently
creditworthy to perform the obligations such assignee or sublessee will have under this Lease; 
 (ii) The intended use of the Premises by
the assignee or sublessee is not for general office use; 
 (iii) The intended use of the Premises by the assignee or sublessee would
materially increase the pedestrian or vehicular traffic to the Premises or the Building; 

  
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 (iv) Occupancy of the Premises by the assignee or sublessee would, in the good faith
judgment of Landlord, violate any agreement binding upon Landlord, the Building or the Land with regard to the identity of tenants, usage in the Building, or similar matters; 

(v) The assignee or sublessee (or any affiliate of the assignee or sublessee) is then negotiating with Landlord or has negotiated with Landlord
within the previous six (6) months regarding occupancy in the Building, or is a current tenant or subtenant within the Building and Landlord will not have vacant space in the Building of comparable size to the subleased premises for such
assignee or sublessee as of the proposed commencement date of such assignment or sublease; 
 (vi) The identity or business reputation of the
assignee or sublessee will, in the good faith judgment of Landlord, tend to damage the goodwill or reputation of the Building; or 
 (vii)
the proposed sublease would result in more than two subleases of portions of the Premises being in effect at any one time during the Lease Term. 

The foregoing criteria shall not exclude any other reasonable basis for Landlord to refuse its consent to such assignment or sublease. 

(f) Notwithstanding any assignment or subletting, Tenant and any guarantor or surety of Tenant’s obligations under this Lease shall at all
times during the initial Term and any subsequent renewals or extensions remain fully responsible and liable for the payment of the Rent and for compliance with all of Tenant’s other obligations under this Lease. In the event that the Rent due
and payable by a sublessee or assignee (or a combination of the rental payable under such sublease or assignment, plus any bonus or other consideration therefor or incident thereto) exceeds the Rent payable under this Lease, then Tenant shall be
bound and obligated to pay Landlord, as additional rent hereunder, one-half (1/2) of all such excess Rent and other excess consideration within thirty (30) days following receipt thereof by Tenant after first deducting all out-of-pocket
costs and expenses reasonably incurred by Tenant in connection with such assignment or subleasing including broker’s fees, attorneys’ fees, free rent, improvement allowances and other reasonable concessions. 

(g) If this Lease is assigned or if the Premises is subleased (whether in whole or in part), or in the event of the mortgage or pledge of
Tenant’s leasehold interest, or grant of any concession or license within the Premises, or if the Premises are occupied in whole or in part by anyone other than Tenant, then upon a default by Tenant hereunder beyond any applicable notice and
cure periods. Landlord may collect the amounts due to the Tenant from the assignee, sublessee, mortgagee, pledgee, concessionee or licensee or other occupant and shall, except to the extent payable to the Landlord as set forth in the preceding
sub-paragraph, apply the amount collected to the next Rent payable hereunder; and all such amounts collected by Tenant after such default shall be held in deposit for Landlord and immediately forwarded to Landlord. No such transaction or collection
of such amounts or application thereof by Landlord, however, shall be deemed a waiver of these provisions or a release of Tenant from the further performance by Tenant of its covenants, duties, or obligations hereunder. 

  
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 (h) If Tenant effects an assignment or sublease or requests the consent of Landlord to any
proposed assignment or sublease, then Tenant shall, upon demand, pay Landlord an amount equal to Landlord’s any reasonable attorneys’ and paralegal fees and costs which Landlord may incur in connection with such proposed assignment or
sublease or request for consent, not to exceed Two Thousand Five Hundred Dollars ($2,500.00) with respect to a typical assignment or sublease using Landlord’s standard form of consent with minor edits. Acceptance of reimbursement of
Landlord’s attorneys’ and paralegal fees shall in no event obligate Landlord to consent to any proposed assignment or sublease or grant a consent hereunder. 

(i) Notwithstanding any provision of this Lease to the contrary, in the event this Lease is assigned to any person or entity pursuant to the
provisions of the Bankruptcy Code, any and all monies or other consideration payable or otherwise to be delivered in connection with such assignment shall be paid or delivered to Landlord, shall be and remain the exclusive property of Landlord and
shall not constitute the property of Tenant or Tenant’s estate within the meaning of the Bankruptcy Code. All such money and other consideration not paid or delivered to Landlord shall be held in trust for the benefit of Landlord and shall be
promptly paid or delivered to Landlord. 
 (j) The joint and several liability of the Tenant named herein and any immediate and remote
successor in interest of Tenant (by assignment or otherwise), and the due performance of the obligations of this Lease on Tenant’s part to be performed or observed, shall not in any way be discharged, released or impaired by any
(a) agreement that modifies any of the rights or obligations of the parties under this Lease, (b) stipulation that extends the time within which an obligation under this Lease is to be performed, (c) waiver of the performance of an
obligation required under this Lease, or (d) failure to enforce any of the obligations set forth in this Lease. 
 (k) If Tenant is any
form of partnership, a withdrawal or change, voluntary, involuntary or by operation of law of any partner, or the dissolution of the partnership, shall be deemed a voluntary assignment. If Tenant consists of more than one (1) person, a
purported assignment, voluntary or involuntary or by operation of law from one (1) person to the other shall be deemed a voluntary assignment. If Tenant is a corporation or limited liability entity, any dissolution, merger, consolidation or
other reorganization of Tenant, or sale or other transfer of a ownership interest(s) in Tenant that results in a change of voting control of Tenant, or the sale of at least fifty percent (50%) of the value of the assets of Tenant shall be
deemed a voluntary assignment. 
 (l) Notwithstanding anything to the contrary contained in this Paragraph 11, provided that the
conditions described below in this sentence have been satisfied prior to or upon such assignment or subleasing, Tenant may, without Landlord’s prior written consent, sublet all or a portion of the Premises or assign this Lease to (i) a
subsidiary, affiliate, division, corporation, partnership, limited liability company or joint venture controlling, controlled by or under common control with Tenant, (ii) a successor entity resulting from a merger, consolidation, or
nonbankruptcy reorganization by Tenant, or (iii) a purchaser of substantially all of Tenant’s assets (each a “Permitted Transfer”), provided in all cases (i), (ii) and (iii) that the successor entity, assignee,
purchaser or subtenant has a net worth equal to or greater than those of Tenant prior to the effective date of this Lease and a liquid net worth sufficient for Tenant to continually perform its obligations under the Lease, and assumes in writing for
the benefit of Landlord, this Lease and all of Tenant’s obligations under this Lease. If any assignment or subleasing occurs without such an assumption and/or without Landlord’s consent as provided in this Paragraph 11 above, Tenant
shall be deemed for all purposes to be in an Event of Default under this Lease. In all events, Tenant shall remain fully liable under this Lease. 

  
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 12. DEFAULT. 

(a) Events of Default. The occurrence of any one or more of the following events shall constitute an “Event of Default” under
this Lease by Tenant: (i) Tenant shall fail to pay Rent or any other rental or sums payable by Tenant hereunder within five (5) business days after Landlord notifies Tenant in writing of such nonpayment; provided, however, Landlord shall
only be obligated to provide such written notice to Tenant one (1) time within any calendar year and in the event Tenant fails to timely pay Rent or any other sums for a second time during any calendar year, then Tenant shall be in immediate
default for such late payment and Landlord shall have no obligation or duty to provide notice of such non-payment to Tenant prior to declaring an Event of Default under this Lease; (ii) the failure by Tenant to observe or perform any of the
express or implied covenants or provisions of this Lease to be observed or performed by Tenant, other than monetary failures as specified in Paragraph 12(a)(i) above, where such failure shall continue for a period of thirty (30) days
after written notice thereof from Landlord to Tenant; provided, however, that if the nature of Tenant’s default is curable and is such that more than thirty (30) days are reasonably required for its cure, then Tenant shall not be deemed to
be in default if Tenant shall commence such cure within said thirty (30) day period and thereafter diligently prosecute such cure to completion, which completion shall occur not later than sixty (60) days from the date of such notice from
Landlord; (iii) the making by Tenant or any guarantor hereof of any general assignment for the benefit of creditors, (iv) the filing by or against Tenant or any guarantor hereof of a petition to have Tenant or any guarantor hereof adjudged
a bankrupt or a petition for reorganization or arrangement under any law relating to bankruptcy (unless, in the case of a petition filed against Tenant or any guarantor hereof, the same is dismissed within sixty (60) days), (v) the
appointment of a trustee or receiver to take possession of substantially all of Tenant’s assets located at the Premises or of Tenant’s interest in this Lease or of substantially all of guarantor’s assets, where possession is not
restored to Tenant or guarantor within sixty (60) days, (vi) the attachment, execution or other judicial seizure of substantially all of Tenant’s assets located at the Premises or of substantially all of guarantor’s assets or of
Tenant’s interest in this Lease where such seizure is not discharged within sixty (60) days; (vii) any material representation or warranty made by Tenant or guarantor in this Lease or any other document delivered in connection with
the execution and delivery of this Lease or pursuant to this Lease proves to be incorrect in any material respect provided, however, that an Event of Default shall not be deemed to have occurred if the representation or warranty was made in good
faith without the intention to mislead Landlord and the underlying situation to which such representation or warranty relates is capable of being corrected without Landlord’s incurring any loss or damage, then Tenant shall have a reasonable
period, not to exceed ten (10) business days, within which to correct the underlying situation and provide Landlord with an accurate representation or warranty with respect thereto; (viii) Tenant or guarantor shall be liquidated or
dissolved or shall begin proceedings towards its liquidation or dissolution. 

  
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 Upon the occurrence of any one or more of such Events of Default, Landlord may, in addition
to all other remedies available at law or in equity, at its sole option without notice (i) at any time after such Event of Default (and following the issuance of any notice to quit if required by Law) and, after commencing summary process
proceedings if required by Law, re-enter the Premises in the name of the whole and repossess the same as of Landlord’s former estate, and dispossess Tenant and any other persons or entities and their respective property and effects from the
Premises, without being deemed guilty of any manner of trespass and without prejudice to any other rights or remedies, and/or (ii) give to Tenant three (3) days’ notice of cancellation of this Lease, in which event this Lease and the
Lease Term shall terminate (whether or not the Term shall have commenced) with the same force and effect as if the date set forth in the notice was the Expiration Date stated herein, and Tenant shall then quit and surrender the Premises to Landlord,
but Tenant shall remain liable for damages as provided in this Paragraph 12. Any notice of cancellation of the Lease Term may be given simultaneously with any notice of default given to Tenant. 

(b) Possession/Reletting. If any Event of Default occurs and Landlord reenters the Premises or terminates this Lease as aforesaid. 

(i) Surrender of Possession. Tenant shall quit and surrender the Premises to Landlord. 

(ii) Disposition of Tenant’s Property. In the event of any such termination, entry or re-entry, Landlord shall have the rights to
remove and store Tenant’s property and that of persons claiming by, through or under Tenant at the sole risk and expense of Tenant and, if Landlord so elects, (x) to sell such property at public auction or private sale and apply the net
proceeds to the payment of all sums due to Landlord from Tenant and pay the balance, if any, to Tenant, or (y) to dispose of such property in any manner in which Landlord shall elect, Tenant hereby agreeing to the fullest extent permitted by
Law that it shall have no right, title or interest in any property remaining in the Premises after such termination, entry or re-entry. 

(iii) Landlord’s Reletting. Landlord, at Landlord’s option, may relet all or any part of the Premises from time to time,
either in the name of Landlord or otherwise, to such tenant or tenants, for any term ending before, on or after the Expiration Date, at such rental and upon such other conditions (which may include concessions and free rent periods) as Landlord, in
its sole discretion, may determine. Landlord shall have no obligation to and shall not be liable for refusal or failure to relet the Premises or any part thereof, or, in the event of any such reletting, for refusal or failure to collect any rent due
upon any such reletting and Tenant hereby waives, to the extent permitted by applicable Laws, any obligation Landlord may have to mitigate Tenant’s damages; and no such refusal or failure shall relieve Tenant of, or otherwise affect, any
liability under this Lease. Notwithstanding the foregoing, Landlord will use reasonable efforts to relet the Premises after Tenant vacates the Premises; however, the marketing of the Premises in a manner similar to the manner in which Landlord
markets other premises within Landlord’s control in the Building shall be deemed to have satisfied Landlord’s obligation to use “reasonable efforts.” In no event shall Landlord be required to (i) solicit or entertain
negotiations with any other prospective tenants for the Premises unless and until Landlord obtains full and complete possession of the Premises, including the final and unappealable legal right to relet the Premises free of any claim of Tenant,
(ii) lease the Premises to a tenant whose proposed use, in Landlord’s reasonable judgment, will be unacceptable, (iii) relet the Premises prior to leasing any other vacant space in the Building, suitable for the use of the prospective
tenant, (iv) lease the Premises for a rental rate less than the current fair market rent then prevailing for similar space in the Building, or (v) enter 

  
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into a lease with any proposed tenant that does not have, in Landlord’s reasonable opinion, sufficient financial wherewithal and resources to satisfy its financial obligations under the
prospective lease. Landlord shall be entitled to take into account in connection with any such reletting of the Premises all relevant factors which would be taken into account by a sophisticated landlord in securing a replacement tenant for the
Premises including the first class quality of the Building, matters of tenant mix, and the financial responsibility of any such replacement tenant. Landlord, at Landlord’s option, may make such alterations, decorations and other physical
changes in and to the Premises as Landlord, in its sole reasonable discretion, considers advisable or necessary in connection with such reletting or proposed reletting. No reasonable action or inaction by Landlord in connection with such reletting
shall relieve Tenant of any liability under this Lease or otherwise affecting any such liability. 
 (iv) Remedies Not Exclusive. The
specified remedies to which Landlord may resort hereunder are not intended to be exclusive of any remedies or means of redress to which Landlord may, at any time, be entitled lawfully and Landlord may invoke any remedy (including the remedy of
specific performance) allowed at law or in equity as if specific remedies were not herein provided for. 
 (v) Summary Process. Upon
any Event of Default of Tenant, or the expiration or termination of this Lease, Landlord shall have the right of summary process under M.G.L.A. Chapter 239, and/or other applicable statues, and such other rights to recover possession as permitted by
applicable Laws. 
 (c) Tenant’s Waiver. To the maximum extent permitted by law, after (A) Tenant shall have been
dispossessed by judgment or by warrant of any court or judge, (B) any re-entry by Landlord, or (C) any expiration or early termination of the term of this Lease, whether such dispossess, re-entry, expiration or termination shall be by
operation of law or pursuant to the provisions of this Lease, Tenant, on its own behalf and on behalf of all persons or entities claiming through or under Tenant, including all creditors, hereby waives all rights which Tenant and all such persons or
entities might otherwise have (i) to serve notice of Tenant’s intention to re-enter or notice of Tenant’s intention to institute legal proceedings, or (ii) to redeem, or to re-enter or repossess the Premises, or (iii) to
restore the operation of this Lease. The words “re-enter,” “re-entry” and “re-entered” as used in this Lease shall not be deemed to be restricted to their technical legal meanings. 

(d) Tenant’s Breach. Upon the breach or threatened breach by Tenant, or any persons or entities claiming through or under Tenant,
of any term, covenant or condition of this Lease, whether or not such breach or threatened breach constitutes an Event of Default, Landlord shall have the right to enjoin such breach or threatened breach and to invoke any other remedy allowed in
equity. The rights to invoke the remedies set forth above shall not preclude Landlord from invoking any other remedy under this Lease or allowed at law or in equity should such breach or threated breach become an Event of Default. 

  
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 (e) Landlord’s Damages. If this Lease and the Lease Term, or Tenant’s right
to possession of the Premises shall terminate, or Landlord shall re-enter the Premises, as provided in this Paragraph 12, then, in any of such events: 

(i) Tenant shall pay to Landlord all items of Rent payable under this Lease by Tenant to Landlord prior to the date of termination or
repossession; 
 (ii) Landlord may retain all monies, if any, paid by Tenant to Landlord, whether as prepaid Rent, a security deposit or
otherwise, which monies, to the extent not otherwise applied to amounts due and owing to Landlord, shall be credited by Landlord against any damages payable by Tenant to Landlord; 

(iii) Tenant shall pay to Landlord, in monthly installments over the balance of the Lease Term, on the days specified in this Lease for payment
of installments of Base Rent, any “Deficiency” (as hereinafter defined); it being understood that Landlord shall be entitled to recover the Deficiency installment from Tenant each month as the same shall arise, and no suit to collect the
amount of the Deficiency installment for any month, shall prejudice Landlord’s right to collect the Deficiency installment for any subsequent month by a similar proceeding; and 

(iv) whether or not Landlord shall have collected any monthly Deficiency installment, Tenant shall pay to Landlord, on demand (the date of such
payment is the “Payment Date”), at the election of Landlord, in lieu of any further Deficiency installments and as liquidated and agreed final damages, the Present Value (as hereinafter defined) plus any Deficiency Installments
theretofore to have been paid, but which were not paid. Present Value is intended to reflect a discounted value of the amount by which the Rent for the period which otherwise would have constituted the unexpired portion of the Lease Term at the date
of termination or repossession (assuming the Operating Expenses Additional Rent and Taxes Additional Rent during such period to be the same as was payable for the year immediately preceding such termination or re-entry, increased in each succeeding
year by four percent (4%) (on a compounded basis)) exceeds the then fair and reasonable rental value of the Premises for the same period. To find the Present Value, the difference described in the preceding sentence shall be calculated for each
month of the period in question and such difference shall be discounted to the amount which, if invested on the Payment Date at 6% per annum, would yield on the date such monthly payment of Rent would have otherwise been due, in the amount of
such difference; and the sum of all such differences so discounted shall be the “Present Value”. If, before presentation of proof of such liquidated damages to any court, commission or tribunal, the Premises, or any part thereof, shall
have been relet by Landlord for the period which otherwise would have constituted the unexpired portion of the Lease Term, or any part thereof, the amount of rent reserved upon such reletting shall be deemed prima facie, to be the fair and
reasonable rental value for the part or the whole of the Premises so relet during the term of the reletting. 

“Deficiency” shall mean the difference between (a) the Base Rent and Additional Rent for the period which otherwise
would have constituted the unexpired portion of the Lease Term (assuming the Additional Rent for each year thereof to be the same as was payable for the year immediately preceding such termination or re-entry), and (b) the net amount, if any,
of rents or other amounts whether or not characterized as rents) collected under any reletting effected pursuant to the provisions of the Lease for any part of such period (after first deducting from such rents all third party out of pocket expenses
incurred by Landlord in connection with the termination of this Lease, Landlord’s re-entry upon the Premises and such reletting, including repossession costs, brokerage commissions, reasonable attorneys’ fees and disbursements, and
alteration costs). Deficiency installments shall be calculated on the net rent collectable from third parties with respect to the Premises by reason of reletting with respect to the period for which the Deficiency installment is being paid. 

  
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 (f) Reletting. If the Premises, or any part thereof, shall be relet together with
other space in the Building, the rents collected or reserved under any such reletting and the expenses of any such reletting shall be equitably apportioned for the purposes of this Paragraph 12. Tenant shall not be entitled to any rents
collected or payable under any reletting, whether or not such rents exceed the Base Rent reserved in this Lease. Nothing contained in this Paragraph 12 shall be deemed to limit or preclude the recovery by Landlord from Tenant of the maximum
amount allowed to be obtained as damages under this Lease, or of any sums or damages to which Landlord may be entitled in addition to the damages set forth in this Paragraph 12. 

(g) Interest. If any payment of Rent is not paid when due, interest shall accrue on such payment, from the date such payment became due
until paid at the Default Rate. Tenant acknowledges that late payment by Tenant of Rent will cause Landlord to incur costs not contemplated by this Lease, the exact amount of such costs being extremely difficult and impracticable to fix. Such costs
include, without limitation, processing and accounting charges, and late charges that may be imposed on Landlord by the terms of any note secured by a mortgage covering the Building or the Land (or any part thereof). Therefore, in addition to
interest, if any amount is not paid when due, a late charge equal to five percent (5%) of such amount shall be assessed, provided, however, that on two (2) occasions during any calendar year of the Term, Landlord shall give Tenant notice
of such late payment and Tenant shall have a period of five (5) days thereafter in which to make such payment before any late charge is assessed. Such interest and late charges shall constitute Additional Rent payable by Tenant, and are
separate and cumulative and are in addition to and shall not diminish or represent a substitute for any of Landlord’s rights or remedies under any other provision of this Lease or otherwise available at law or in equity. The term
“Default Rate” as used in this Lease shall mean the lesser of (A) the rate announced from time to time by Wells Fargo Bank or, if Wells Fargo Bank ceases to exist or ceases to publish such rate, then the rate announced from
time to time by the largest (as measured by deposits) chartered bank operating in the State, as its “prime rate” or “reference rate”, plus five percent (5%), or (B) the maximum rate of interest permitted by Law. 

(h) Other Rights of Landlord. If Tenant fails to pay any Rent when due, Landlord, in addition to any other right or remedy, shall have
the same rights and remedies as in the case of an Event of Default by Tenant in the payment of Base Rent. If Tenant is in arrears in the payment of Rent, Tenant waives Tenant’s right, if any, to designate the items against which any payments
made by Tenant are to be credited, and Landlord may apply any payments made by Tenant to any items Landlord sees fit, regardless of any request by Tenant. 

(i) Landlord’s Right to Perform. Except as specifically provided otherwise in this Lease, all covenants and agreements by Tenant
under this Lease shall be performed by Tenant at Tenant’s sole cost and expense and without any abatement or offset of Rent. If Tenant shall default (after any applicable notice and cure period) in its obligation to pay any sum of money (other
than Base Rent) or perform any other act on its part to be paid or performed hereunder, Landlord may, without waiving or releasing Tenant from any of Tenant’s obligations, make such payment or perform such other act on behalf of Tenant. All
sums so paid by Landlord and all necessary incidental costs incurred by Landlord in performing such other acts shall be payable by Tenant to Landlord within thirty (30) days after demand therefor as Additional Rent. 

  
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 (j) Rights and Remedies Cumulative. All rights, options and remedies of Landlord
contained in this Paragraph 12 and elsewhere in this Lease shall be construed and held to be cumulative, and no one of them shall be exclusive of the other, and Landlord shall have the right to pursue any one or all of such remedies or any
other remedy or relief which may be provided by law or in equity, whether or not stated in this Lease. Nothing in this Paragraph 12 shall be deemed to limit or otherwise affect Tenant’s indemnification of Landlord pursuant to any
provision of this Lease. 
 (k) Costs Upon Event of Default and Litigation. Tenant shall pay to Landlord as Additional Rent all
reasonable third party out of pocket expenses incurred by Landlord in the exercise of any remedy by reason of any Event of Default by Tenant hereunder, including reasonable attorneys’ fees and expenses. 

13. ACCESS; CONSTRUCTION. Landlord reserves from the leasehold estate hereunder, in addition to all other rights reserved by Landlord under this
Lease, the right to use the roof and exterior walls of the Premises and the area beneath, adjacent to and above the Premises, including without limitation the Installation Areas so long as such use does not unreasonably interfere with the right of
Tenant to use the Premises for the purposes permitted under this Lease. Landlord also reserves the right to install, use, maintain, repair, replace and relocate equipment, machinery, meters, pipes, ducts, plumbing, conduits and wiring through the
Premises, which serve other portions of the Building in a manner and in locations which do not unreasonably interfere with Tenant’s use of the Premises. In addition, Landlord shall have free access to any and all mechanical installations of
Landlord or Tenant, including, without limitation, machine rooms, telephone rooms and electrical closets so long as in exercise of such access right. Landlord does not unreasonably interfere with Tenant’s right to use the Premises for the
purposes permitted under this Lease. Tenant agrees that there shall be no construction of partitions or other obstructions which materially interfere with or which threaten to materially interfere with Landlord’s free access thereto, or
materially interfere with the moving of Landlord’s equipment to or from the enclosures containing said installations. Landlord shall at all reasonable times, during normal business hours and after reasonable written (which includes email) or
oral notice, have the right to enter the Premises to inspect the same, to supply janitorial service and any other service to be provided by Landlord to Tenant hereunder, to exhibit the Premises to prospective purchasers, lenders or, during the last
twelve (12) months of the Term, tenants, to post notices of non-responsibility, to alter, improve, restore, rebuild or repair the Premises or any other portion of the Building or the Land, or to maintain or repair the Building or the Common
Areas in connection with construction or excavation work adjacent to or near the Building, or to do any other act permitted to be done by Landlord hereunder, all without being deemed guilty of an eviction of Tenant and without liability for
abatement of Rent or otherwise. For such purposes, Landlord may also erect scaffolding and other necessary structures where reasonably required by the character of the work to be performed, and during such operations may enter upon the Premises and
take into and upon or through the Premises, all materials required to make such repairs, maintenance, alterations or improvements, and may close public entry ways, other public areas, restrooms, stairways or corridors. Landlord shall conduct all
such inspections and/or improvements, alterations and repairs so as to minimize, to the extent reasonably practical and without material 

  
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additional expense to Landlord, any interruption of or interference with the business of Tenant. Tenant hereby waives any claim for damages for any injury or inconvenience to or interference with
Tenant’s business, any loss of occupancy or quiet enjoyment of the Premises, and any other loss occasioned thereby. For each of such purposes, Landlord shall at all times have and retain a key with which to unlock all of the doors in, upon and
about the Premises (excluding Tenant’s vaults and safes, access to which shall be provided by Tenant upon Landlord’s reasonable request). Landlord shall have the right to use any and all means which Landlord may deem proper in an emergency
in order to obtain entry to the Premises or any portion thereof, and Landlord shall have the right, at any time during the Lease Term, to provide whatever access control measures it deems reasonably necessary to the Building, without any
interruption or abatement in the payment of Rent by Tenant. Any entry into the Premises obtained by Landlord by any of such means shall not under any circumstances be construed to be a forcible or unlawful entry into, or a detainer of, the Premises,
or any eviction of Tenant from the Premises or any portion thereof. No provision of this Lease shall be construed as obligating Landlord to perform any repairs, Alterations or decorations to the Premises or the Building or the Land except as
otherwise expressly agreed to be performed by Landlord pursuant to the provisions of this Lease. 
 14. BANKRUPTCY. 

(a) If at any time on or before the Commencement Date there shall be filed by or against Tenant in any court, tribunal, administrative agency
or any other forum having jurisdiction, pursuant to any applicable law, either of the United States or of any state, a petition in bankruptcy or insolvency or for reorganization or for the appointment of a receiver, trustee or conservator of all or
a portion of Tenant’s property, or if Tenant makes an assignment for the benefit of creditors, this Lease shall ipso facto be canceled and terminated and in such event neither Tenant nor any person claiming through or under Tenant or by
virtue of any applicable law or by an order of any court, tribunal, administrative agency or any other forum having jurisdiction, shall be entitled to possession of the Premises and Landlord, in addition to the other rights and remedies given by
Paragraph 12 hereof or by virtue of any other provision contained in this Lease or by virtue of any applicable law, may retain as damages any Rent, Security Deposit or moneys received by it from Tenant or others on behalf of Tenant. 

(b) If, after the Commencement Date, or if at any time during the term of this Lease, there shall be filed against Tenant in any court,
tribunal, administrative agency or any other forum having jurisdiction, pursuant to any applicable law, either of the United States or of any state, a petition in bankruptcy or insolvency or for reorganization or for the appointment of a receiver,
trustee or conservator of all or a portion of Tenant’s property, and the same is not dismissed after sixty (60) calendar days, or if Tenant makes an assignment for the benefit of creditors, this Lease, at the option of Landlord exercised
within a reasonable time after notice of the happening of any one or more of such events, may be canceled and terminated and in such event neither Tenant nor any person claiming through or under Tenant or by virtue of any statute or of an order of
any court shall be entitled to possession or to remain in possession of the Premises, but shall forthwith quit and surrender the Premises, and Landlord, in addition to the other rights and remedies granted by Paragraph 12 hereof or by virtue
of any other provision contained in this Lease or by virtue of any applicable law, may retain as damages any Rent, Security Deposit or moneys received by it from Tenant or others on behalf of Tenant. 

  
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 15. SUBSTITUTION OF PREMISES. Subject to the conditions specified in this Paragraph 15,
Landlord reserves the right without Tenant’s consent, on ninety (90) days’ prior written notice to Tenant, to substitute other premises within the Building for the Premises, provided, however, that such right shall not be exercised
prior to the expiration of Lease Year 2, and may only be exercised one (1) time during the Term. In each such case, the substituted premises shall (a) contain at least substantially the same Rentable Area as the Premises and no lower in
the Building than the original Premises, (b) contain comparable tenant improvements using new materials and finishes and substantially the same layout and amount of interior glass as the original Premises, and (c) be made available to
Tenant at the then current annual Rent for such space, which in no event, shall exceed the per square foot annual Rent for the Premises in effect under this Lease for the Premises at the time of such substitution. Landlord shall pay all reasonable
moving expenses of Tenant incidental to such substitution of premises, the reasonable cost of new stationery and reasonable costs and expenses incurred by Tenant for telecommunications cabling and wiring. Any physical relocation of Tenant under this
Paragraph 15 shall be undertaken only non a weekend or legal holiday and shall in no event cause any material disruption to Tenant’s business operations. 

16. SUBORDINATION; ATTORNMENT; ESTOPPEL CERTIFICATES. 

(a) Tenant agrees that this Lease and the rights of Tenant hereunder shall be subject and subordinate to any and all mortgages, deeds of trust,
master leases, ground leases or other security documents and any and all modifications, renewals, extensions, consolidations and replacements thereof (collectively, “Security Documents”) which now or hereafter constitute a lien upon
or encumber the Land, the Building or the Premises. Such subordination shall be effective without the necessity of the execution by Tenant of any additional document for the purpose of evidencing or effecting such subordination. In addition, the
holder of any such Security Documents (e.g. mortgagee, trustee, master lessor or the like), may effect, by providing notice thereof to Tenant to subordinate or cause to be subordinated any such Security Documents to this Lease and in such
case, in the event of the termination or transfer of Landlord’s estate or interest in the Land or the Building by reason of any termination or foreclosure of any such Security Documents, Tenant shall, notwithstanding such subordination, attorn
to and become the Tenant of the successor-in-interest to Landlord. Furthermore, Tenant shall within fifteen (15) days of demand therefor execute any instruments or other documents which may be required by Landlord or the holder of any Security
Document and specifically shall execute, acknowledge and deliver within fifteen (15) days of demand therefor a subordination of this lease in the form required by the holder of the Security Document requesting the document; the failure to do so
by Tenant within such time period shall be a material default hereunder. 
 (b) If as a result of a proceeding brought for default under any
ground or master lease to which this Lease is subject, the interest of the Landlord is transferred or in the event of such transfer by reason of foreclosure or the exercise of the power of sale under any mortgage, deed of trust or other Security
Document made by Landlord covering the Premises, Tenant shall attorn to and recognize such transferee as Landlord under this Lease, provided such transferee expressly agrees in writing to be bound to all future obligations by the terms of this
Lease, provided, however, it shall be a condition of the obligation of the transferee to be so bound that, if so requested by the transferee, Tenant shall enter into a new lease with that transferee or any successor to such transferee on the same
terms and conditions as are contained in this Lease (for the unexpired term of this Lease then remaining). Tenant hereby waives its rights under any current or future law which gives or purports to give Tenant any right to terminate or otherwise
adversely affect this Lease and the obligations of Tenant hereunder in the event of any such foreclosure proceeding or sale. 

  
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 (c) Tenant shall, upon not less than ten (10) days’ prior notice by Landlord,
execute, acknowledge and deliver to Landlord a statement in writing certifying to those facts for which certification has been requested by Landlord or any current or prospective purchaser, holder of any Security Document, ground lessor or master
lessor, or stating any limitations on any certification, including, but without limitation, that (i) this Lease is unmodified and in full force and effect (or if there have been modifications, that the same is in full force and effect as
modified and stating the modifications), (ii) the dates to which the Base Rent, Additional Rent and other charges hereunder have been paid, if any, and (iii) whether or not to the best knowledge of Tenant, Landlord is in default in the
performance of any covenant, agreement or condition contained in this Lease and, if so, specifying each such default of which Tenant may have knowledge. The form of the statement attached hereto as Exhibit D is hereby approved by
Tenant for use pursuant to this sub-paragraph (c); however, at Landlord’s option, Landlord shall have the right to use other forms for such purpose. Tenant’s failure to execute and deliver such statement within such time shall, at
the option of Landlord, constitute an Event of Default under this Lease and, in any event, shall be conclusive upon Tenant that this Lease is in full force and effect without modification except as may be represented by Landlord in any such
certificate prepared by Landlord and delivered to Tenant for execution. Any statement delivered pursuant to this Paragraph 16 may be relied upon by any prospective purchaser of the fee or of the Building or any mortgagee, ground lessor or
other like encumbrances thereof or any assignee of any such encumbrance upon the Building or the Land. 
 17. SALE BY LANDLORD; TENANT’S
REMEDIES; NONRECOURSE LIABILITY. 
 (a) In the event of a sale or conveyance by Landlord of the Building or the Land, Landlord shall
be released from any and all liability under this Lease. If the Security Deposit has been deposited by Tenant to Landlord prior to such sale or conveyance, Landlord shall transfer the Security Deposit to the purchaser, and upon delivery to Tenant of
notice thereof, Landlord shall be discharged from any further liability in reference thereto. 
 (b) Landlord shall not be in default of any
obligation of Landlord hereunder unless Landlord fails to perform any of its obligations under this Lease within thirty (30) days after receipt of written notice of such failure from Tenant; provided, however, that if the nature of
Landlord’s obligation is such that more than thirty (30) days are required for its performance, Landlord shall not be in default if Landlord commences to cure such default within the thirty (30) day period and thereafter diligently
prosecutes the same to completion. All obligations of Landlord under this Lease will be binding upon Landlord only during the period of its ownership of the Building and not thereafter. All obligations of Landlord hereunder shall be construed as
covenants, not conditions; and, except as may be otherwise expressly provided in this Lease, Tenant may not terminate this Lease for breach of Landlord’s obligations hereunder. 

  
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 (c) Notwithstanding anything contained in this Lease to the contrary, the obligations of
Landlord under this Lease (including any actual or alleged breach or default by Landlord) do not constitute personal obligations of the individual partners, directors, officers, trustees, members or shareholders of Landlord or Landlord’s
members or partners, and Tenant shall not seek recourse against the individual partners, directors, officers, trustees, members or shareholders of Landlord or against Landlord’s members or partners or against any other persons or entities
having any interest in Landlord, or against any of their personal assets for satisfaction of any liability with respect to this Lease. Any liability of Landlord for a default by Landlord under this Lease, or a breach by Landlord of any of its
obligations under the Lease, shall be limited solely to its interest in the Land and Building, and in no event shall any personal liability be asserted against Landlord in connection with this Lease nor shall any recourse be had to any other
property or assets of Landlord, its partners, directors, officers, trustees, members, shareholders or any other persons or entities having any interest in Landlord. Tenant’s sole and exclusive remedy for a default or breach of this Lease by
Landlord shall be either (i) an action for damages, or (ii) an action for injunctive relief; Tenant hereby waiving and agreeing that Tenant shall have no offset rights or right to terminate this Lease on account of any breach or default by
Landlord under this Lease. Under no circumstances whatsoever shall Landlord ever be liable for punitive, consequential or special damages under this Lease and Tenant waives any rights it may have to such damages under this Lease in the event of a
breach or default by Landlord under this Lease. 
 (d) Notwithstanding anything contained in this Lease to the contrary, the obligations of
Tenant under this Lease (including any actual or alleged breach or default by Tenant) do not constitute personal obligations of the individual partners, directors, officers, trustees, members or shareholders of Tenant or Tenant’s members or
partners, and Landlord shall not seek recourse against the individual partners, directors, officers, trustees, members or shareholders of Tenant for a breach or default by Tenant in its obligations under this Lease. With the exception of (i) a
holdover by Tenant of the Lease Term, and (ii) a breach or default or of Tenant’s obligations under this Lease with regard to Hazardous Materials (and without limiting any indemnification obligations of Tenant with regard to Hazardous
Materials), Tenant shall never be liable for punitive, consequential or special damages under this Lease and subject to the foregoing exceptions, Landlord waives any rights it may have to such damages under this Lease in the event of a breach or
default by Tenant under this Lease. 
 (e) As a condition to the effectiveness of any notice of default given by Tenant to Landlord, Tenant
shall also concurrently give such notice under the provisions of Paragraph 17(b) to each beneficiary under a Security Document encumbering the Land or the Building of whom Tenant has received written notice (such notice to specify the address
of the beneficiary). In the event Landlord shall fail to cure any breach or default within the time period specified in sub-paragraph (b), then prior to the pursuit of any remedy therefor by Tenant, each such beneficiary shall have an
additional thirty (30) days within which to cure such default, or if such default cannot reasonably be cured within such period, then each such beneficiary shall have such additional time as shall be necessary to cure such default, provided
that within such thirty (30) day period, such beneficiary has commenced and is diligently pursuing the remedies available to it which are necessary to cure such default (including, without limitation, as appropriate, commencement of foreclosure
proceedings). 

  
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 18. PARKING: COMMON AREAS. 

(a) The parking garage associated with the Building (the “Parking Garage”) is leased to and operated by a third party (the
“Parking Garage Operator”), pursuant to which Landlord has certain rights to designate a certain number of parking spaces for use by tenants in the Building. Commencing on the Commencement Date, Landlord shall designate for
Tenant’s use parking passes for up to the number of parking spaces in the Parking Garage specified in Item 14 of Basic Lease Provisions, which shall be on an unreserved, non-exclusive basis. Monthly parking charges shall be
paid directly to the Parking Garage Operator either by Tenant, to the extent that Tenant designates itself, as an entity, as the holder of certain passes, or by the individual designated by Tenant as the holder of designated parking passes, in any
case at prevailing rates of the Parking Garage Operator from time to time. A default by Tenant, its officers or employees beyond any applicable notice and cure periods in the agreement with such operator shall relieve Landlord from any liability to
provide parking spaces under this Lease. Notwithstanding anything to the contrary set forth in this Lease, Tenant shall have the right to arrange directly with the Parking Garage Operator to rent additional parking spaces in the Parking Garage on a
month-to-month basis 
 (b) Subject to sub-paragraph (c) below and the remaining provisions of this Lease, Tenant shall have, as
appurtenant to the Premises, the nonexclusive right, in common with others, to the use of such entrances, lobbies, fire vestibules, restrooms (excluding restrooms on any full floors leased by a tenant), mechanical areas, ground floor corridors,
elevators and elevator foyers, electrical and janitorial closets, telephone and equipment rooms, loading and unloading areas, the plaza areas surrounding the Building and located on the Land, ramps, drives, stairs, and similar access ways and
service ways and other common areas and facilities in and adjacent to the Building and located on the Land as are designated from time to time by Landlord for the general nonexclusive use and enjoyment of Landlord, Tenant and the other tenants of
the Building and their respective employees, agents, representatives, licensees and invitees (“Common Areas”). The use of such Common Areas shall be subject to the Rules and Regulations (as defined in Paragraph 19(f))
and the provisions of any covenants, conditions and restrictions affecting the Building or the Land. Tenant shall keep all of the Common Areas free and clear of any obstructions created or permitted by Tenant or resulting from Tenant’s
operations, and shall use the Common Areas only for normal activities and ingress and egress by Tenant and its employees, agents, representatives, licensees and invitees to and from the Premises, the Building or the Land. If, in the reasonable
opinion of Landlord, unauthorized persons are using the Common Areas by reason of the presence of Tenant in the Premises, Tenant, upon demand of Landlord, shall correct such situation by appropriate action or proceedings against all such
unauthorized persons. Nothing herein shall affect the rights of Landlord at any time to remove any such unauthorized persons from said areas or to prevent the use of any of said areas by unauthorized persons. Landlord reserves the right to make such
changes, alterations, additions, deletions, improvements, repairs or replacements in or to the Building (excluding the Premises) and the Common Areas as Landlord may reasonably deem necessary or desirable, including, without limitation, adding
floors and making changes in the location, size, shape and number of entrances, loading areas, landscaped areas and walkways, changes and reductions in corridors and lobbies and the installation of kiosks, planters, sculptures, displays, escalators,
mezzanines, and other structures, facilities, amenities and features therein, and changes for the purpose of connection with or entrance into or use of the Property in conjunction with any adjoining or adjacent building or buildings, now existing or
hereafter constructed; provided, however, that (i) there shall be no unreasonable permanent 

  
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obstruction of access to or use of the Premises resulting therefrom, and (ii) Landlord shall use commercially reasonable efforts to minimize any interruption with Tenant’s use and
occupancy of and access to the Premises. Notwithstanding any provision of this Lease to the contrary, the Common Areas shall not in any event be deemed to be a portion of or included within the Premises leased to Tenant and the Premises shall not be
deemed to be a portion of the Common Areas. This Lease is granted subject to the terms hereof, the rights and interests of third parties under existing liens, ground leases, easements and encumbrances affecting such property, all zoning regulations,
rules, ordinances, building restrictions and other laws and regulations now in effect or hereafter adopted by any governmental authority having jurisdiction over the Land or Building or any part thereof. 

(c) Notwithstanding any provision of this Lease to the contrary, Landlord specifically reserves the right to redefine the term
“Building” for purposes of equitably allocating and calculating Operating Expenses and Real Estate Taxes so as to include or exclude areas as Landlord shall from time to time reasonably determine or specify (and any such
determination or specification shall be without prejudice to Landlord’s right to revise thereafter such determination or specification). In addition, Landlord shall have the right to contract or otherwise arrange for amenities, services or
utilities that are included within the definition of Operating Expenses under this Lease to be provided on a common or shared basis to both the Building (i.e., the area defined in the Basic Lease Provisions as the “Building”) and
adjacent areas not included within the Building (the “Additional Area”), so long as the cost of such amenities, services or utilities is allocated to the Building and such Additional Area on a reasonable and equitable basis and not
for the purpose of shifting to the Building a greater share of Operating Expenses or Real Estate Taxes. In the case where the definition of the Building is revised for purposes of the allocation or determination of Operating Expenses and Real Estate
Taxes to include both the Building and the Additional Area, Tenant’s Proportionate Share shall be appropriately revised to equal the percentage share represented by the Premises of the Rentable Area contained within the Building and the
Additional Area in the aggregate, and Base Operating Expenses and Base Real Estate Taxes shall be adjusted appropriately to reflect the amount that would have been reasonably included therein had Operating Expenses and Taxes been determined on the
same basis during the respective Base Years in order to maintain an equitable allocation of increases in Operating Expenses and Real Estate Taxes over that associated with the respective Base Years notwithstanding such adjustments. Landlord shall
have the sole right to determine which portions of the Building and other areas, if any, shall be served by common management, operation, maintenance and repair. Landlord shall have the exclusive rights to the airspace above and around, and the
subsurface below, the Premises and other portions of the Building and Land. 
 19. MISCELLANEOUS. 

(a) Attorneys’ Fees. In the event of any legal action or proceeding brought by either party against the other arising out of this
Lease, the prevailing party shall be entitled to recover reasonable attorneys’ fees and costs (including, without limitation, court costs and expert witness fees) incurred in such action. Such amounts shall be included in any judgment rendered
in any such action or proceeding and the parties shall request that the trier of fact determine which is the prevailing party. 

  
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 (b) Waiver. No waiver by Landlord of any provision of this Lease or of any breach by
Tenant hereunder shall be deemed to be a waiver of any other provision hereof, or of any subsequent breach by Tenant. Landlord’s consent to or approval of any act by Tenant requiring Landlord’s consent or approval under this Lease shall
not be deemed to render unnecessary the obtaining of Landlord’s consent to or approval of any subsequent act of Tenant. No act or thing done by Landlord or Landlord’s agents during the term of this Lease shall be deemed an acceptance of a
surrender of the Premises, unless in writing signed by Landlord. The delivery of the keys to any employee or agent of Landlord shall not operate as a termination of the Lease or a surrender of the Premises. The acceptance of any Rent by Landlord
following a breach of this Lease by Tenant shall not constitute a waiver by Landlord of such breach or any other breach unless such waiver is expressly stated in a writing signed by Landlord. 

(c) Notices. Any notice, demand, request, consent, approval, disapproval or certificate (“Notice”) required or desired
to be given under this Lease shall be in writing and given by certified mail, return receipt requested, by personal delivery or by a nationally recognized overnight delivery service (such as Federal Express or UPS) providing a receipt for delivery.
Notices may not be given by facsimile. The date of giving any Notice shall be deemed to be the date upon which delivery is actually made by one of the methods described in this Paragraph 19(c) (or attempted if said delivery is refused or
rejected). If a Notice is received on a Saturday, Sunday or legal holiday, it shall be deemed received on the next business day. All notices, demands, requests, consents, approvals, disapprovals, or certificates shall be addressed at the respective
addresses specified in Item 15 of the Basic Lease Provisions or to such other addresses as may be specified by written notice from Landlord to Tenant or Tenant to Landlord. Either party may change its address by giving reasonable
advance written Notice of its new address in accordance with the methods described in this Paragraph; provided, however, no notice of either party’s change of address shall be effective until fifteen (15) days after the addressee’s
actual receipt thereof. For the purpose of this Lease, each party’s counsel may provide Notices to the other on behalf of their respective clients and such notices shall be binding on the receiving party as if such notices have been provided
directly by the notifying party. 
 (d) Access Control. Landlord shall be the sole determinant of the type and amount of any access
control or courtesy guard services to be provided to the Building, if any. IN ALL EVENTS, LANDLORD SHALL NOT BE LIABLE TO TENANT, AND TENANT HEREBY WAIVES ANY CLAIM AGAINST LANDLORD, FOR (I) ANY TRESPASS OR CRIMINAL ENTRY OF THIRD PARTIES INTO
THE PREMISES OR THE BUILDING, (II) ANY DAMAGE TO PERSONS, OR (III) ANY LOSS OF PROPERTY IN AND ABOUT THE PREMISES, THE BUILDING OR THE LAND, BY OR FROM ANY TRESPASS OR CRIMINAL ACTS OF THIRD PARTIES, REGARDLESS OF ANY ACTION, INACTION, FAILURE,
BREAKDOWN, MALFUNCTION AND/OR INSUFFICIENCY OF THE ACCESS CONTROL OR COURTESY GUARD SERVICES PROVIDED BY LANDLORD, IF ANY Tenant shall provide such supplemental security services and shall install within the Premises such supplemental security
equipment, systems and procedures as may reasonably be required for the protection of its employees and invitees, provided that Tenant shall coordinate such services and equipment with any security provided by Landlord. The determination of the
extent to which such supplemental security equipment, systems and procedures are reasonably required shall be made in the sole judgment, and shall be the sole responsibility, of Tenant. Tenant acknowledges that it has neither received nor relied
upon any representation or warranty made by or on behalf of 

  
 -48- 

 
Landlord with respect to the safety or security of the Premises or the Building or any part thereof or the extent or effectiveness of any security measures or procedures now or hereafter provided
by Landlord, and further acknowledges that Tenant has made its own independent determinations with respect to all such matters. Without limiting the generality of the foregoing, Landlord shall have the right to limit or prevent access to the
Property, shut down elevator service, activate elevator emergency controls, or otherwise take such action or preventative measures deemed necessary by Landlord for the safety of tenants or other occupants of the Property or the protection of the
Property and other property located thereon or therein, in case of fire, invasion, insurrection, riot, civil disorder, public excitement or other dangerous condition, or threat thereof. 

(e) Storage. Any storage space at any time leased to Tenant hereunder shall be used exclusively for storage. Notwithstanding any other
provision of this Lease to the contrary, (i) Landlord shall have no obligation to provide heating, cleaning, water or air conditioning therefor, and (ii) Landlord shall be obligated to provide to such storage space only such electricity as
will, in Landlord’s judgment, be adequate to light said space as storage space. 
 (f) Holding Over. If Tenant retains possession
of the Premises after the termination or expiration of the Lease Term, then Tenant shall, at Landlord’s election become a tenant at sufferance (and not a tenant at will), such possession shall be subject to immediate termination by Landlord at
any time, and all of the other terms and provisions of this Lease (excluding any expansion or renewal option or other similar right or option) shall be applicable during such holdover period, except that Tenant shall pay Landlord from time to time,
upon demand, as Base Rent for the holdover period, an amount equal to one hundred fifty percent (150%) of the Base Rent in effect on the termination date for the first thirty (30) days of any holdover and two hundred percent (200%) of
the Base Rent in effect on the termination date thereafter, computed on a monthly basis for each month or part thereof during such holding over. All other payments (including payment of Additional Rent) shall continue under the terms of this Lease.
In addition, if Tenant holds over for thirty (30) or more days following the termination date, Tenant shall be liable for all damages incurred by Landlord as a result of such holding over. No holding over by Tenant, whether with or without
consent of Landlord, shall operate to extend this Lease except as otherwise expressly provided, and this Paragraph shall not be construed as consent for Tenant to retain possession of the Premises. 

(g) Condition of Premises. EXCEPT AS OTHERWISE EXPRESSLY PROVIDED IN THIS LEASE, LANDLORD HEREBY DISCLAIMS ANY EXPRESS OR IMPLIED
REPRESENTATION OR WARRANTY THAT THE PREMISES ARE SUITABLE FOR TENANT’S INTENDED PURPOSE OR USE, WHICH DISCLAIMER IS HEREBY ACKNOWLEDGED BY TENANT. EXCEPT AS OTHERWISE PROVIDED IN THIS LEASE THE TAKING OF POSSESSION BY TENANT SHALL BE CONCLUSIVE
EVIDENCE THAT TENANT: 
 (i) ACCEPTS THE PREMISES, THE BUILDING AND LEASEHOLD IMPROVEMENTS AS SUITABLE FOR THE PURPOSES FOR WHICH THE
PREMISES WERE LEASED; 
 (ii) ACCEPTS THE PREMISES AND BUILDING AS BEING IN GOOD AND SATISFACTORY CONDITION; 

  
 -49- 

 (iii) WAIVES ANY DEFECTS IN THE PREMISES AND ITS APPURTENANCES EXISTING NOW OR IN THE
FUTURE, EXCEPT THAT TENANT’S TAKING OF POSSESSION SHALL NOT BE DEEMED TO WAIVE LANDLORD’S COMPLETION OF MINOR FINISH WORK ITEMS THAT DO NOT INTERFERE WITH TENANT’S OCCUPANCY OF THE PREMISES OR LANDLORD’S ONGOING MAINTENANCE AND
REPAIR OBLIGATIONS UNDER OTHER PROVISIONS OF THIS LEASE; AND 
 (iv) WAIVES ALL CLAIMS BASED ON ANY IMPLIED WARRANTY OF SUITABILITY OR
HABITABILITY. 
 (h) Quiet Possession. Provided Tenant pays the Rent reserved hereunder when due or within any applicable period of
notice and grace and Tenant and observing and performing all of the covenants, conditions and provisions on Tenant’s part to be observed and performed hereunder within applicable periods of notice and grace, Tenant shall have quiet possession
of the Premises for the term hereof without hindrance or ejection by any person lawfully claiming under Landlord, subject to the provisions of this Lease and to the provisions of any (i) covenants, conditions and restrictions, (ii) master
lease, or (iii) Security Documents to which this Lease is subordinate or may be subordinated. Notwithstanding the foregoing, Landlord shall have the right to grant to any person or entity the right to conduct any business or render any service
at the Property, whether or not it is the same or similar to the use made of the Premises by the Tenant; and shall have access to any mail chutes located on the Premises according to the rules of the United States Postal Service. 

(i) Matters of Record. Except as otherwise provided herein, this Lease and Tenant’s rights hereunder are subject and subordinate to
all matters affecting Landlord’s title to the Land and Building recorded in the Real Property Records of the County in which the Building is located, prior to and subsequent to the date hereof, including, without limitation, all covenants,
conditions and restrictions. Tenant agrees for itself and all persons in possession or holding under it that it will comply with and not violate any such covenants, conditions and restrictions or other matters of record to the extent such covenants,
conditions and restrictions or other matters of record do not conflict with Tenant’s rights and obligations under this Lease. Landlord reserves the right, from time to time, to grant such easements, rights and dedications as Landlord deems
necessary or desirable, and to cause the recordation of parcel maps and covenants, conditions and restrictions affecting the Premises, the Building or the Land, as long as such easements, rights, dedications, maps, and covenants, conditions and
restrictions do not materially interfere with the use of the Premises by Tenant. At Landlord’s request, Tenant shall join in the execution of any of the aforementioned documents. 

(j) Successors and Assigns. Except as otherwise provided in this Lease, all of the covenants, conditions and provisions of this Lease
shall be binding upon and shall inure to the benefit of the parties hereto and their respective heirs, personal representatives, successors and assigns. Tenant shall attorn to each purchaser, successor or assignee of Landlord. 

  
 -50- 

 (k) Brokers. Each party warrants to the other that it has had no dealings with any
real estate broker or agent in connection with the negotiation of this Lease, excepting only the Landlord’s broker named in Item 13 of the Basic Lease Provisions and that it knows of no other real estate broker or agent who
is or might be entitled to a commission in connection with this Lease. Landlord shall be responsible for all brokerage commissions or similar payments due to such broker named in Item 13 of the Basic Lease Provisions. Tenant hereby
agrees to indemnify, defend and hold Landlord harmless for, from and against all claims for any brokerage commissions, finders’ fees or similar payments by any persons acting on behalf of Tenant, and all costs, expenses and liabilities incurred
in connection with such claims, including reasonable attorneys’ fees and costs. Landlord hereby agrees to indemnify, defend and hold Tenant harmless for, from and against all claims for any brokerage commissions, finders’ fees or similar
payments by any persons acting on behalf of Landlord, and all costs, expenses and liabilities incurred in connection with such claims, including reasonable attorneys’ fees and costs. 

(l) Building Name and Signage. Landlord shall have the right at any time to install, affix and maintain any and all signs on the
exterior and on the interior of the Building as Landlord may, in Landlord’s sole discretion, desire. Tenant shall not use the name of the Building or use pictures or illustrations of the Building in advertising or other publicity or for any
purpose other than as the address of the business to be conducted by Tenant in the Premises, without the prior written consent of Landlord. Additionally, Landlord shall have the exclusive right at all times during the Lease Term to change, modify,
add to or otherwise alter the name, number, or designation of the Building, and Landlord shall not be liable for claims or damages of any kind which may be attributed thereto or result therefrom. Notwithstanding the foregoing, Landlord hereby
consents to Tenant placing signage on the exterior of the Premises at Tenant’s entrance doors, at Tenant’s sole cost and expense, in accordance with Landlord’s reasonable rules with respect thereto and Tenant may, at its option have
signage on the electronic Building directory provided for tenants in the lobby of the Building, standard elevator lobby signage in the applicable floor, and an additional directional sign on the
31st floor at a location and of a size as shall be mutually agreed by Landlord and Tenant. 

(m) Examination of Lease. Submission of this instrument for examination or signature by Tenant does not constitute a reservation of or
option for lease, and it is not effective as a lease or otherwise until execution by and delivery to both Landlord and Tenant. 
 (n)
Time. Time is of the essence of this Lease and each and all of those provisions of the Lease that are time dependent. 
 (o)
Interpretation; Defined Terms and Marginal Headings. The words “Landlord” and “Tenant” as used herein shall include the plural as well as the singular and for purposes of Articles 5, 7, 13 and
18, the term Landlord shall include Landlord, its employees, contractors and agents. The marginal headings and titles to the articles of this Lease are not a part of this Lease and shall have no effect upon the construction or interpretation
of any part hereof. Wherever this Lease requires Landlord to provide a customary service or to act in a reasonable manner (whether in incurring an expense, establishing a rule or regulation, providing an approval or consent, or performing any other
act), this Lease shall be deemed also to provide that whether such service is customary or such conduct is reasonable shall be determined by reference to the practices of owners of buildings that (i) are comparable to the Building in size, age,
class, quality and location, and (ii) at Landlord’s option, have been, or are being prepared to be, certified under the U.S. Green Building Council’s Leadership in Energy and Environmental Design (LEED) rating system or a similar
rating system. 

  
 -51- 

 (p) Conflict of Laws; Prior Agreements; Separability. This Lease shall be governed by
and construed pursuant to the laws of the Commonwealth of Massachusetts. This Lease contains all of the agreements of the parties hereto with respect to any matter covered or mentioned in this Lease. No prior agreement, understanding or
representation pertaining to any such matter shall be effective for any purpose. No provision of this Lease may be amended or added to except by an agreement in writing signed by the parties hereto or their respective successors in interest. The
illegality, invalidity or unenforceability of any provision of this Lease shall in no way impair or invalidate any other provision of this Lease, and such remaining provisions shall remain in full force and effect. 

(q) Authority. If Tenant is a corporation or limited liability company, Tenant and each individual executing this Lease on behalf of
Tenant hereby covenants and warrants that Tenant is a duly authorized and existing corporation or limited liability company, that Tenant has and is qualified to do business in the State, that the corporation or limited liability company has full
right and authority to enter into this Lease, and that each person signing on behalf of the corporation is authorized to do so. If Tenant is a partnership or trust, each individual executing this Lease on behalf of Tenant hereby covenants and
warrants that he is duly authorized to execute and deliver this Lease on behalf of Tenant in accordance with the terms of such entity’s partnership or trust agreement. Tenant shall provide Landlord on demand with such evidence of such authority
as Landlord shall reasonably request, including, without limitation, resolutions, certificates and opinions of counsel. This Lease shall not be construed to create a partnership, joint venture or similar relationship or arrangement between Landlord
and Tenant hereunder. 
 (r) Joint and Several Liability. If two or more individuals, corporations, partnerships or other business
associations (or any combination of two or more thereof) shall sign this Lease as Tenant, the liability of each such individual, corporation, partnership or other business association to pay Rent and perform all other obligations hereunder shall be
deemed to be joint and several, and all notices, payments and agreements given or made by, with or to any one of such individuals, corporations, partnerships or other business associations shall be deemed to have been given or made by, with or to
all of them. In like manner, if Tenant shall be a partnership or other business association, the members of which are, by virtue of statute or federal law, subject to personal liability, then the liability of each such member shall be joint and
several. 
 (s) Rental Allocation. For purposes of Section 467 of the Internal Revenue Code of 1986, as amended from time to
time, Landlord and Tenant hereby agree to allocate all Rent to the period in which payment is due, or if later, the period in which Rent is paid. 

(t) Rules and Regulations. Tenant agrees to comply with all non-discriminatory rules and regulations of general applicability to tenants
and other users of the Building from time to time made by Landlord (the “Rules and Regulations”), as the same may be amended or supplemented from time to time upon reasonable notice to Tenant. Landlord shall not be liable to Tenant
for the failure of any other tenant or any of its assignees, subtenants, or their respective agents, employees, representatives, invitees or licensees to conform to the Rules and Regulations. 

  
 -52- 

 (u) Joint Product. This Agreement is the result of arms-length negotiations between
Landlord and Tenant and their respective attorneys experienced in lease transactions of office space in the Commonwealth of Massachusetts. Accordingly, neither party shall be deemed to be the author of this Lease and this Lease shall not be
construed against either party. Furthermore, each of the provisions was negotiated in view of the entire transaction including the type and location of the property, the rental, the term and the respective rights, obligations and remedies of the
Landlord and Tenant. As a result, the rights, obligations and remedies agreed to herein are, as negotiated, a part of the transaction as a whole. Neither party intends that the absence of a termination remedy being specified herein for a particular
action or lack of action by the other party implies that the parties intended any such remedy to be inferred. Without limiting the generality of the foregoing, in no event shall Tenant have the right to terminate or cancel this lease as a result of
any default by Landlord or breach by Landlord of its covenants or any warranties or promises hereunder, except in the case of a wrongful eviction of Tenant from the demised premises (constructive or actual) by Landlord or as expressly provided in
this Lease. 
 (v) Financial Statements. Upon Landlord’s written request, Tenant shall promptly furnish Landlord, from time to
time, with the most current audited annual financial statements prepared in accordance with generally accepted accounting principles, certified by Tenant and an independent auditor to be true and correct, reflecting Tenant’s then current
financial condition. Landlord and its affiliates and investors shall keep such financial statements confidential, provided that Landlord shall be permitted to deliver such financial statements to a lender, purchaser or lessor or a prospective
lender, purchaser or lessor, subject to such recipient’s execution of a commercially reasonable confidentiality agreement. Landlord and Tenant agree that the form attached hereto as Exhibit E is a commercially reasonable form of
confidentiality agreement. 
 (w) Force Majeure. Any prevention, delay or stoppage due to strikes, lockouts, labor disputes, acts of
God, acts of war, terrorism, terrorist activities, inability to obtain services, labor, or materials or reasonable substitutes therefore, governmental actions, civil commotions, fire, flood, earthquake or other casualty, and other causes beyond the
reasonable control of the party obligated to perform, except with respect to the obligations imposed with regard to Rent and other charges to be paid by Tenant pursuant to this Lease and except as to Tenant’s obligations under Article 6
and Article 8 of this Lease and Paragraph 19(f) of this Lease (collectively, a “Force Majeure”), notwithstanding anything to the contrary contained in this Lease, shall excuse the performance of such party for a period
equal to any such prevention, delay or stoppage and, therefore, if this Lease specifies a time period for performance of an obligation of either party, that time period shall be extended by the period of any delay in such party’s performance
caused by a Force Majeure. 
 (x) Counterparts. This Lease may be executed in several counterparts, each of which shall be deemed an
original, and all of which shall constitute but one and the same instrument. 
 (y) Waiver of Right to Jury Trial. LANDLORD AND
TENANT WAIVE THEIR RESPECTIVE RIGHTS TO TRIAL BY JURY OF ANY CONTRACT OR TORT CLAIM, COUNTERCLAIM, CROSS-COMPLAINT, OR CAUSE OF ACTION IN ANY ACTION, PROCEEDING, OR HEARING BROUGHT BY EITHER PARTY AGAINST THE OTHER ON ANY MATTER ARISING OUT OF OR IN
ANY WAY CONNECTED WITH THIS LEASE, THE RELATIONSHIP OF LANDLORD AND TENANT, OR TENANT’S USE OR OCCUPANCY OF THE LEASED PREMISES, INCLUDING WITHOUT LIMITATION ANY CLAIM OF INJURY OR DAMAGE OR THE ENFORCEMENT OF ANY REMEDY UNDER ANY CURRENT OR
FUTURE LAW, STATUTE, REGULATION, CODE, OR ORDINANCE. 

  
 -53- 

 (z) Office and Communications Services. Landlord has advised Tenant that certain
office and communications services may be offered to tenants of the Building by a concessionaire under contract to Landlord (“Provider”). Tenant shall be permitted to contract with Provider for the provision of any or all of such
services on such terms and conditions as Tenant and Provider may agree. Tenant acknowledges and agrees that: (i) Landlord has made no warranty or representation to Tenant with respect to the availability of any such services, or the quality,
reliability or suitability thereof; (ii) the Provider is not acting as the agent or representative of Landlord in the provision of such services, and Landlord shall have no liability or responsibility for any failure or inadequacy of such
services, or any equipment or facilities used in the furnishing thereof, or any act or omission of Provider, or its agents, employees, representatives, officers or contractors; (iii) Landlord shall have no responsibility or liability for the
installation, alteration, repair, maintenance, furnishing, operation, adjustment or removal of any such services, equipment or facilities; and (iv) any contract or other agreement between Tenant and Provider shall be independent of this Lease,
the obligations of Tenant hereunder, and the rights of Landlord hereunder, and, without limiting the foregoing, no default or failure of Provider with respect to any such services, equipment or facilities, or under any contract or agreement relating
thereto, shall have any effect on this Lease or give to Tenant any offset or defense to the full and timely performance of its obligations hereunder, or entitle Tenant to any abatement of rent or additional rent or any other payment required to be
made by Tenant hereunder, or constitute any accrual or constructive eviction of Tenant, or otherwise give rise to any other claim of any nature against Landlord. 

(aa) OFAC Compliance. 
 (i)
Certification. Tenant certifies, represents, warrants and covenants that: 
 (i) It is not acting and will not act,
directly or indirectly, for or on behalf of any person, group, entity, or nation named by any Executive Order or the United States Treasury Department as a terrorist, “Specially Designated National and Blocked Person”, or other banned or
blocked person, entity, nation or transaction pursuant to any law, order, rule, or regulation that is enforced or administered by the Office of Foreign Assets Control; and 

(ii) It is not engaged in this transaction, directly or indirectly on behalf of, or instigating or facilitating this
transaction, directly or indirectly on behalf of, any such person, group, entity or nation. 
 (ii) Indemnity. Tenant hereby agrees to
defend (with counsel reasonably acceptable to Landlord), indemnify and hold harmless Landlord and the Landlord Indemnitees from and against any and all Claims arising from or related to any such breach of the foregoing certifications,
representations, warranties and covenants. 

  
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 (bb) OFAC Compliance. 

(i) Certification. Landlord certifies, represents, warrants and covenants that: 

(i) It is not acting and will not act, directly or indirectly, for or on behalf of any person, group, entity, or nation named
by any Executive Order or the United States Treasury Department as a terrorist, “Specially Designated National and Blocked Person”, or other banned or blocked person, entity, nation or transaction pursuant to any law, order, rule, or
regulation that is enforced or administered by the Office of Foreign Assets Control; and 
 (ii) It is not engaged in this
transaction, directly or indirectly on behalf of, or instigating or facilitating this transaction, directly or indirectly on behalf of, any such person, group, entity or nation. 

(iii) Indemnity. Landlord hereby agrees to defend (with counsel reasonably acceptable to Tenant), indemnify and hold harmless
Tenant and the Tenant Affiliates from and against any and all Claims arising from or related to any such breach of the foregoing certifications, representations, warranties and covenants. 

(cc) No Easement For Light. Air And View. This Lease conveys to Tenant no rights for any light, air or view. No diminution of light, air
or view, or any impairment of the visibility of the Premises from inside or outside the Building, by any structure or other object that may hereafter be erected (whether or not by Landlord) shall entitle Tenant to any reduction of Rent under this
Lease, constitute an actual or constructive eviction of Tenant, result in any liability of Landlord to Tenant, or in any other way affect this Lease or Tenant’s obligations hereunder. 

(dd) Nondisclosure of Lease Terms. Tenant agrees that the terms of this Lease are confidential and constitute proprietary information of
Landlord, and that disclosure of the terms hereof could adversely affect the ability of Landlord to negotiate with other tenants. Tenant hereby agrees that Tenant and its partners, officers, directors, employees, agents, real estate brokers and
sales persons and attorneys shall not disclose the terms of this Lease to any other person without Landlord’s prior written consent, except to any accountants of Tenant in connection with the preparation of Tenant’s financial statements or
tax returns, to an assignee of this Lease or subtenant of the Premises, or to an entity or person to whom disclosure is require by applicable law or in connection with any action brought to enforce this Lease. 

(ee) ERISA. Tenant is not an “employee benefit plan” as defined in Section 3(3) of the Employee Retirement Income
Security Act of 1974 (“ERISA”), which is subject to Title I of ERISA, or a “plan” as defined in Section 4975(e)(1) of the Internal Revenue Code of 1986, which is subject to Section 4975 of the Internal Revenue
Code of 1986; and (b) the assets of Tenant do not constitute “plan assets” of one or more such plans for purposes of Title I of ERISA or Section 4975 of the Internal Revenue Code of 1986; and (c) Tenant is not a
“governmental plan” within the meaning of Section 3(32) of ERISA, and assets of Tenant do not constitute plan assets of one or more such plans; or (d) transactions by or with Tenant are not in violation of state statutes
applicable to Tenant regulating investments of and fiduciary obligations with respect to governmental plans. 

[SIGNATURE PAGES TO FOLLOW] 

  
 -55- 

 SIGNATURE PAGE TO OFFICE LEASE 

BY AND BETWEEN T-C 33 ARCH STREET LLC, AS LANDLORD, 

AND KARUNA PHARMACEUTICALS, INC., AS TENANT 

IN WITNESS WHEREOF, the parties have executed this Lease to be effective as of the Date of this Lease. 

 

			
	LANDLORD:
	
	 T-C 33 ARCH STREET LLC,
 a Delaware
limited liability company

 
			
		
	 By:
	 	Teachers Insurance and Annuity Association of America, Managing Investor

 
					
			
		 	By:	 	 /s/ William K. Arkamowitz

		 	Name:	 	 William K. Arkamowitz

		 	Title:	 	 Authorized Signatory

					
		 	Date of Execution:	 	  

 [Signature Page] 

 SIGNATURE PAGE TO OFFICE LEASE 

BY AND BETWEEN T-C 33 ARCH STREET LLC, AS LANDLORD, 

AND KARUNA PHARMACEUTICALS, INC., AS TENANT 
  

			
	TENANT:
	
	 KARUNA PHARMACEUTICALS, INC.,
 a
Delaware corporation

		
	By:	 	/s/ Andrew Miller
		 	its: COO
		 	hereunto duly authorized

 [Signature Page]EX-10.14

 Exhibit 10.14 

AMENDED AND RESTATED EMPLOYMENT AGREEMENT 

This Amended and Restated Employment Agreement (“Agreement”) is made between Karuna Therapeutics, Inc., a Delaware corporation (the
“Company”), and Steven Paul, M.D. (the “Executive”) and is made effective as of the closing of the Company’s first underwritten public offering of its equity securities pursuant to an effective registration statement under
the Securities Act of 1933, as amended (the “Effective Date”). 
 WHEREAS, the Company (formerly, Karuna Pharmaceuticals, Inc.)
and the Executive are parties to an employment agreement, dated August 1, 2018, as amended (the “Prior Agreement”), which the Company and the Executive intend to amend and restate in its entirety; and 

WHEREAS, the Company desires to continue to employ the Executive and the Executive desires to continue to be employed by the Company on the
new terms and conditions contained herein. 
 NOW, THEREFORE, in consideration of the mutual covenants and agreements herein contained and
other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the parties agree to amend and restate the Prior Agreement in its entirety as follows: 

1. Employment. 
 (a)
Term. The term of this Agreement shall commence on the Effective Date and continue until terminated in accordance with the provisions hereof (the “Term”). The Executive’s employment with the Company shall be “at
will,” meaning that the Executive’s employment may be terminated by the Company or the Executive at any time and for any reason, subject to the terms of this Agreement. 

(b) Position and Duties. During the Term, the Executive shall serve as the President and Chief Executive Officer of the Company
(“CEO”) and Chairman of the Board and shall have such powers and duties as may from time to time be prescribed by the Board of Directors (the “Board”). In addition, the Executive shall serve on the Board as long as the Executive
remains the Chief Executive Officer of the Company, provided the Executive shall resign from the Board and from any related positions upon ceasing to serve as CEO for any reason. The Executive shall devote his full time efforts to the business and
affairs of the Company; provided that he shall regularly work in the Company’s offices, currently located in Boston, Massachusetts, at least two days per week; provided further that he will be required to travel as necessary for
business-related purposes. Notwithstanding the foregoing, the Executive may serve on other boards of directors, with the approval of the Board, or engage in religious, charitable or other community activities or other business activities as long as
such services and activities are disclosed to the Board and do not interfere with the Executive’s performance of his duties to the Company, provided the Executive shall not perform an operational or fundraising role for another for-profit entity while serving as CEO. The Company specifically acknowledges and agrees to the Executive’s existing and continued service on the Board of Directors of Alnylam Pharmaceuticals, Inc., Sage
Therapeutics, Inc., and Voyager Therapeutics, Inc. 

 2. Compensation and Related Matters. 

(a) Base Salary. During the Term, the Executive’s initial base salary shall be paid at the rate of $500,000 per year. The
Executive’s base salary shall be reviewed annually by the Board or the Compensation Committee of the Board (the “Compensation Committee”). The base salary in effect at any given time is referred to herein as “Base Salary.”
The Base Salary shall be payable in a manner that is consistent with the Company’s usual payroll practices for executive officers. 

(b) Incentive Compensation. During the Term, the Executive shall be eligible to receive cash incentive compensation as determined by
the Board or the Compensation Committee from time to time. The Executive’s initial target annual incentive compensation shall be 50 percent of his Base Salary (the “Target Bonus”) and be based on predetermined metrics
as determined by the Board or the Compensation Committee after consultation with the Executive. Except as otherwise provided herein, to earn incentive compensation, the Executive must be employed by the Company on the day such incentive compensation
is paid. 
 (c) Expenses. The Executive shall be entitled to receive prompt reimbursement for all reasonable expenses incurred by him
during the Term in performing services hereunder, in accordance with the policies and procedures then in effect and established by the Company for its executive officers. 

(d) Other Benefits. During the Term, the Executive shall be eligible to participate in or receive benefits under the Company’s
employee benefit plans in effect from time to time, subject to the terms of such plans. 
 (e) Vacations. During the Term, the
Executive shall be entitled to take paid time off in accordance with the Company’s applicable paid time off policy for executives as may be in effect from time to time. The Executive shall also be entitled to all paid holidays given by the
Company to its executive officers. 
 (f) Equity. The equity awards held by the Executive shall continue to be governed by the
terms and conditions of the Company’s applicable equity incentive plan(s) and the applicable award agreement(s) governing the terms of such equity awards held by the Executive (collectively, the “Equity Documents”); provided, however,
and notwithstanding anything to the contrary in the Equity Documents, (i) Section 5(b)(iii) of this Agreement shall apply in the event of a termination by the Company without Cause or by the Executive for Good Reason that does not occur
within the Change in Control Period (as such terms are defined below) and (ii) Section 6(a)(ii) of this Agreement shall apply in the event of a termination by the Company without Cause or by the Executive for Good Reason in either event
within the Change in Control Period. 

  
 2 

 3. Termination. During the Term, the Executive’s employment hereunder may be
terminated without any breach of this Agreement under the following circumstances: 
 (a) Death. The Executive’s employment
hereunder shall terminate upon his death. 
 (b) Disability. The Company may terminate the Executive’s employment if he is
disabled and unable to perform the essential functions of the Executive’s then existing position or positions under this Agreement with or without reasonable accommodation for a period of 180 days (which need not be consecutive) in any 12-month period. If any question shall arise as to whether during any period the Executive is disabled so as to be unable to perform the essential functions of the Executive’s then existing position or
positions with or without reasonable accommodation, the Executive may, and at the request of the Company shall, submit to the Company a certification in reasonable detail by a physician selected by the Company to whom the Executive or the
Executive’s guardian has no reasonable objection as to whether the Executive is so disabled or how long such disability is expected to continue, and such certification shall for the purposes of this Agreement be conclusive of the issue. The
Executive shall cooperate with any reasonable request of the physician in connection with such certification. If such question shall arise and the Executive shall fail to submit such certification, the Company’s determination of such issue
shall be binding on the Executive. Nothing in this Section 3(b) shall be construed to waive the Executive’s rights, if any, under existing law including, without limitation, the Family and Medical Leave Act of 1993, 29 U.S.C. §2601
et seq. and the Americans with Disabilities Act, 42 U.S.C. §12101 et seq. 
 (c) Termination by Company for Cause.
The Company may terminate the Executive’s employment hereunder for Cause. For purposes of this Agreement, “Cause” shall mean: (i) conduct by the Executive constituting a material act of misconduct in connection with the
performance of his duties, including, without limitation, willful failure or refusal to perform material responsibilities that have been requested by the Board, misappropriation of funds or property of the Company or any of its subsidiaries or
affiliates other than the occasional, customary and de minimis use of Company property for personal purposes, or dishonesty to the Board with respect to any material matter; (ii) the commission by the Executive of any acts satisfying the
elements of felony or a misdemeanor involving moral turpitude, deceit, dishonesty or fraud, or any conduct by the Executive that would reasonably be expected to result in material injury or reputational harm to the Company or any of its subsidiaries
or affiliates if he were retained in his position; (iii) continued non-performance by the Executive of his duties hereunder (other than by reason of the Executive’s physical or mental illness,
incapacity or disability) which has continued for more than 30 days following written notice of such non-performance from the Board; (iv) a breach by the Executive of any of the provisions contained in
Section 8 of this Agreement or the Restrictive Covenants Agreements; (v) a material violation by the Executive of the Company’s written employment policies; or (vi) failure to cooperate with a bona fide internal investigation or
an investigation by regulatory or law enforcement authorities, after being instructed by the Company to cooperate, or the willful destruction or failure to preserve documents or other materials known to be relevant to such investigation or the
inducement of others to fail to cooperate or to produce documents or other materials in connection with such investigation. 
 (d)
Termination without Cause. The Company may terminate the Executive’s employment hereunder at any time without Cause. Any termination by the Company of the Executive’s employment under this Agreement which does not constitute a
termination for Cause under Section 3(c) and does not result from the death or disability of the Executive under Section 3(a) or (b) shall be deemed a termination without Cause. 

  
 3 

 (e) Termination by the Executive. The Executive may terminate his employment
hereunder at any time for any reason, including but not limited to Good Reason. For purposes of this Agreement, “Good Reason” shall mean that the Executive has complied with the “Good Reason Process” (hereinafter defined)
following the occurrence of any of the following events: (i) a material diminution in the Executive’s responsibilities, authority or duties; (ii) a material diminution in the Executive’s Base Salary except for across-the-board salary reductions based on the Company’s financial performance similarly affecting all or substantially all senior management employees of the Company;
(iii) a material change in the geographic location at which the Executive provides services to the Company; or (iv) the material breach of this Agreement by the Company. “Good Reason Process” shall mean that (i) the
Executive reasonably determines in good faith that a “Good Reason” condition has occurred; (ii) the Executive notifies the Company in writing of the first occurrence of the Good Reason condition within 60 days of the first occurrence
of such condition; (iii) the Executive cooperates in good faith with the Company’s efforts, for a period not less than 30 days following such notice (the “Cure Period”), to remedy the condition; (iv) notwithstanding such
efforts, the Good Reason condition continues to exist; and (v) the Executive terminates his employment within 60 days after the end of the Cure Period. If the Company cures the Good Reason condition during the Cure Period, Good Reason shall be
deemed not to have occurred. 
 4. Notice and Date of Termination. 

(a) Notice of Termination. Except for termination as specified in Section 3(a), any termination of the Executive’s employment
by the Company or any such termination by the Executive shall be communicated by written Notice of Termination to the other party hereto. For purposes of this Agreement, a “Notice of Termination” shall mean a notice which shall indicate
the specific termination provision in this Agreement relied upon. 
 (b) Date of Termination. “Date of Termination” shall
mean: (i) if the Executive’s employment is terminated by his death, the date of his death; (ii) if the Executive’s employment is terminated on account of disability under Section 3(b) or by the Company for Cause under
Section 3(c), the date on which Notice of Termination is given; (iii) if the Executive’s employment is terminated by the Company under Section 3(d), the date on which a Notice of Termination is given or another date as specified
in the Notice of Termination; (iv) if the Executive’s employment is terminated by the Executive under Section 3(e) without Good Reason, 30 days after the date on which a Notice of Termination is given, and (v) if the
Executive’s employment is terminated by the Executive under Section 3(e) for Good Reason, the date on which a Notice of Termination is given after the end of the Cure Period. Notwithstanding the foregoing, in the event that the Executive
gives a Notice of Termination to the Company, the Company may unilaterally accelerate the Date of Termination and such acceleration shall not result in a termination by the Company for purposes of this Agreement. 

  
 4 

 5. Compensation Upon Termination. 

(a) Termination Generally. If the Executive’s employment with the Company is terminated for any reason, the Company shall pay or
provide to the Executive (or to his authorized representative or estate) (i) any Base Salary earned through the Date of Termination, unpaid expense reimbursements (subject to, and in accordance with, Section 2(c) of this Agreement) and
unused vacation that accrued through the Date of Termination on or before the time required by law but in no event more than 30 days after the Executive’s Date of Termination; and (ii) any vested benefits the Executive may have under any
employee benefit plan of the Company through the Date of Termination, which vested benefits shall be paid and/or provided in accordance with the terms of such employee benefit plans (collectively, the “Accrued Benefit”). 

(b) Termination by the Company without Cause or by the Executive with Good Reason. During the Term, if the
Executive’s employment is terminated by the Company without Cause as provided in Section 3(d), or the Executive terminates his employment for Good Reason as provided in Section 3(e), then the Company shall pay the Executive his
Accrued Benefit. In addition, subject to (i) the Executive signing a separation agreement in a form and manner satisfactory to the Company, which shall contain, among other provisions, a general release of claims in favor of the Company and
related persons and entities, confidentiality, return of property and non-disparagement and a reaffirmation of all of the Executive’s Continuing Obligations (as defined below), (the “Separation
Agreement and Release”) and (ii) the Separation Agreement and Release becoming fully irrevocable, all within 60 days after the Date of Termination (or such shorter period as set forth in the Separation Agreement and Release), which shall
include a seven (7) business day revocation period : 
 (i) the Company shall pay the Executive an amount equal to
twelve (12) months of the Executive’s then-current Base Salary; and 
 (ii) the Company shall pay the Executive a pro-rata amount of the Executive’s Target Bonus based on the performance of the Company and consistent with bonuses paid to other Company executives, both as determined by the Board in its reasonable good faith
discretion; and 
 (iii) notwithstanding anything to the contrary in any applicable option agreement or other equity award
agreement, all outstanding equity grants subject to time-based vesting held by the Executive that would have vested in the twelve (12) month period following the Date of Termination shall immediately accelerate and become fully exercisable or
nonforfeitable as of the Date of Termination; and 
 (iv) subject to the Executive’s copayment of premium amounts at the
applicable active employees’ rate and the Executive’s proper election to receive benefits under the Consolidated Omnibus Budget Reconciliation Act of 1985, as amended (“COBRA”), the Company shall pay to the group health
plan provider, the COBRA provider or the Executive a monthly payment equal to the monthly employer contribution that the Company would have made to the provide health insurance to the Executive if the Executive had remained employed by the Company
until the earliest of (A) the 12-

  
 5 

 
month anniversary of the Date of Termination; (B) the Executive’s eligibility for group medical plan benefits under any other employer’s group medical plan; or (C) the
cessation of the Executive’s continuation rights under COBRA; provided, however, if the Company determines that it cannot pay such amounts to the group health plan provider or the COBRA provider (if applicable) without potentially violating
applicable law (including, without limitation, Section 2716 of the Public Health Service Act), then the Company shall convert such payments to payroll payments directly to the Executive for the time period specified above. Such payments shall
be subject to tax-related deductions and withholdings and paid on the Company’s regular payroll dates. For the avoidance of doubt, the taxable payments described above may be used for any purpose,
including, but not limited to, continuation coverage under COBRA; and 
 The amounts payable under Sections 4(b)(i) and (iv), to the extent taxable, shall
be paid out in substantially equal installments in accordance with the Company’s payroll practice over twelve (12) months commencing within 60 days after the Date of Termination; provided, however, that if the 60-day period begins in one calendar year and ends in a second calendar year, such payments, to the extent they qualify as “non-qualified deferred compensation”
within the meaning of Section 409A of the Internal Revenue Code of 1986, as amended (the “Code”), shall begin to be paid in the second calendar year by the last day of such 60-day period;
provided, further, that the initial payment shall include a catch-up payment to cover amounts retroactive to the day immediately following the Date of Termination. Each payment pursuant to this Agreement is
intended to constitute a separate payment for purposes of Treasury Regulation Section 1.409A-2(b)(2). The amount payable under Section 4(b)(ii) shall be paid on the date bonuses are paid to the
Company’s other executives but no later than March 15 following the year in which the Date of Termination occurs. 
 Notwithstanding the
foregoing, if the Executive breaches any of the provisions contained in Section 8 of this Agreement or the Restrictive Covenants Agreements (as defined below), all payments under this Sections 5(b) shall immediately cease. 

6. Change in Control Payment. The provisions of this Section 6 set forth certain terms of an agreement reached between the
Executive and the Company regarding the Executive’s rights and obligations upon the occurrence of a Change in Control of the Company. These provisions are intended to assure and encourage in advance the Executive’s continued attention and
dedication to his assigned duties and his objectivity during the pendency and after the occurrence of any such event. These provisions shall apply in lieu of, and expressly supersede, the provisions of Section 5(b) regarding severance pay and
benefits upon a termination of employment, if such termination of employment occurs within twelve (12) months after the occurrence of the first event constituting a Change in Control (the “Change in Control Period”). These provisions
shall terminate and be of no further force or effect beginning after the Change in Control Period. 
 (a) Change in Control. During
the Term, if during the Change in Control Period, the Executive’s employment is terminated by the Company without Cause as provided in Section 3(d) or the Executive terminates his employment for Good Reason as provided in
Section 3(e), then, subject to the Executive signing a Separation Agreement and Release that conforms with the requirements of Section 5(b)(i) and the Separation Agreement and Release becoming fully irrevocable, all within 60 days after
the Date of Termination (or such shorter period as set forth in the Separation Agreement and Release), which shall include a seven (7) business day revocation period 

  
 6 

 (i) the Company shall pay the Executive a lump sum in cash in an amount
equal to 1.5 times the sum of (A) the Executive’s then-current Base Salary (or the Executive’s Base Salary in effect immediately prior to the Change in Control, if higher) plus (B) the Executive’s Target Bonus for the then
current year; and 
 (ii) notwithstanding anything to the contrary in any applicable option agreement or other equity award
agreement, all outstanding equity grants subject to time-based vesting held by the Executive shall immediately accelerate and become fully exercisable or nonforfeitable as of the Date of Termination; and 

(iii) subject to the Executive’s copayment of premium amounts at the applicable active employees’ rate and the
Executive’s proper election to receive benefits under the Consolidated Omnibus Budget Reconciliation Act of 1985, as amended (“COBRA”), the Company shall pay to the group health plan provider, the COBRA provider or the
Executive a monthly payment equal to the monthly employer contribution that the Company would have made to the provide health insurance to the Executive if the Executive had remained employed by the Company until the earliest of (A) the 18-month anniversary of the Date of Termination; (B) the Executive’s eligibility for group medical plan benefits under any other employer’s group medical plan; or (C) the cessation of the
Executive’s continuation rights under COBRA; provided, however, if the Company determines that it cannot pay such amounts to the group health plan provider or the COBRA provider (if applicable) without potentially violating applicable law
(including, without limitation, Section 2716 of the Public Health Service Act), then the Company shall convert such payments to payroll payments directly to the Executive for the time period specified above. Such payments shall be subject to tax-related deductions and withholdings and paid on the Company’s regular payroll dates. For the avoidance of doubt, the taxable payments described above may be used for any purpose, including, but not limited
to, continuation coverage under COBRA; and 
 The amounts payable under Sections 6(a)(i) and (iii), to the extent taxable, shall be paid or commence to be
paid within 60 days after the Date of Termination; provided, however, that if the 60-day period begins in one calendar year and ends in a second calendar year, such payments, to the extent they qualify as “non-qualified deferred compensation” within the meaning of Section 409A of the Code, shall be paid or commence to be paid in the second calendar year by the last day of such 60-day period. Notwithstanding the foregoing, if the Executive breaches any of the provisions contained in Section 8 of this Agreement, all payments under this Section 6(a) shall immediately cease. 

  
 7 

 (b) Additional Limitation. 

(i) Anything in this Agreement to the contrary notwithstanding, in the event that the amount of any compensation, payment or distribution by
the Company to or for the benefit of the Executive, whether paid or payable or distributed or distributable pursuant to the terms of this Agreement or otherwise, calculated in a manner consistent with Section 280G of the Code and the applicable
regulations thereunder (the “Aggregate Payments”), would be subject to the excise tax imposed by Section 4999 of the Code, then the Aggregate Payments shall be reduced (but not below zero) so that the sum of all of the Aggregate
Payments shall be $1.00 less than the amount at which the Executive becomes subject to the excise tax imposed by Section 4999 of the Code; provided that such reduction shall only occur if it would result in the Executive receiving a higher
After Tax Amount (as defined below) than the Executive would receive if the Aggregate Payments were not subject to such reduction. In such event, the Aggregate Payments shall be reduced in the following order, in each case, in reverse chronological
order beginning with the Aggregate Payments that are to be paid the furthest in time from consummation of the transaction that is subject to Section 280G of the Code: (1) cash payments not subject to Section 409A of the Code;
(2) cash payments subject to Section 409A of the Code; (3) equity-based payments and acceleration; and (4) non-cash forms of benefits; provided that in the case of all the foregoing
Aggregate Payments all amounts or payments that are not subject to calculation under Treas. Reg. §1.280G-1, Q&A-24(b) or (c) shall be reduced before any
amounts that are subject to calculation under Treas. Reg. §1.280G-1, Q&A-24(b) or (c). 

(ii) For purposes of this Section 6(b), the “After Tax Amount” means the amount of the Aggregate Payments less all federal,
state, and local income, excise and employment taxes imposed on the Executive as a result of the Executive’s receipt of the Aggregate Payments. For purposes of determining the After Tax Amount, the Executive shall be deemed to pay federal
income taxes at the highest marginal rate of federal income taxation applicable to individuals for the calendar year in which the determination is to be made, and state and local income taxes at the highest marginal rates of individual taxation in
each applicable state and locality, net of the maximum reduction in federal income taxes which could be obtained from deduction of such state and local taxes. 

(iii) The determination as to whether a reduction in the Aggregate Payments shall be made pursuant to Section 6(b)(i) shall be made by a
nationally recognized accounting firm selected by the Company (the “Accounting Firm”), which shall provide detailed supporting calculations both to the Company and the Executive within 15 business days of the Date of Termination, if
applicable, or at such earlier time as is reasonably requested by the Company or the Executive. Any determination by the Accounting Firm shall be binding upon the Company and the Executive. 

(c) Definitions. For purposes of this Section 6, the following terms shall have the following meanings: 

“Change in Control” shall mean any of the following: 

(i) any “person,” as such term is used in Sections 13(d) and 14(d) of the Securities Exchange Act of 1934, as amended (the
“Act”) (other than the Company, any of its subsidiaries, or any trustee, fiduciary or other person or entity holding securities under any employee benefit plan or trust of the Company or any of its subsidiaries), together with all
“affiliates” and “associates” (as such terms are defined in Rule 12b-2 

  
 8 

 
under the Act) of such person, shall become the “beneficial owner” (as such term is defined in Rule 13d-3 under the Act), directly or indirectly,
of securities of the Company representing 50 percent or more of the combined voting power of the Company’s then outstanding securities having the right to vote in an election of the Board (“Voting Securities”) (in such case other
than as a result of an acquisition of securities directly from the Company); or 
 (ii) the date a majority of the members of the Board is
replaced during any 12-month period by directors whose appointment or election is not endorsed by a majority of the members of the Board before the date of the appointment or election; or 

(iii) the consummation of (A) any consolidation or merger of the Company where the stockholders of the Company, immediately prior to the
consolidation or merger, would not, immediately after the consolidation or merger, beneficially own (as such term is defined in Rule 13d-3 under the Act), directly or indirectly, shares representing in the
aggregate more than 50 percent of the voting shares of the Company issuing cash or securities in the consolidation or merger (or of its ultimate parent corporation, if any), or (B) any sale or other transfer (in one transaction or a series
of transactions contemplated or arranged by any party as a single plan) of all or substantially all of the assets of the Company. 

Notwithstanding the foregoing, a “Change in Control” shall not be deemed to have occurred for purposes of the foregoing clause
(i) solely as the result of an acquisition of securities by the Company which, by reducing the number of shares of Voting Securities outstanding, increases the proportionate number of Voting Securities beneficially owned by any person to
50 percent or more of the combined voting power of all of the then outstanding Voting Securities; provided, however, that if any person referred to in this sentence shall thereafter become the beneficial owner of any additional shares of
Voting Securities (other than pursuant to a stock split, stock dividend, or similar transaction or as a result of an acquisition of securities directly from the Company) and immediately thereafter beneficially owns 50 percent or more of the
combined voting power of all of the then outstanding Voting Securities, then a “Change in Control” shall be deemed to have occurred for purposes of the foregoing clause (i). 

7. Section 409A. 
 (a)
Anything in this Agreement to the contrary notwithstanding, if at the time of the Executive’s separation from service within the meaning of Section 409A of the Code, the Company determines that the Executive is a “specified
employee” within the meaning of Section 409A(a)(2)(B)(i) of the Code, then to the extent any payment or benefit that the Executive becomes entitled to under this Agreement on account of the Executive’s separation from service would be
considered deferred compensation otherwise subject to the 20 percent additional tax imposed pursuant to Section 409A(a) of the Code as a result of the application of Section 409A(a)(2)(B)(i) of the Code, such payment shall not be
payable and such benefit shall not be provided until the date that is the earlier of (A) six months and one day after the Executive’s separation from service, or (B) the Executive’s death. If any such delayed cash payment is
otherwise payable on an installment basis, the first payment shall include a catch-up payment covering amounts that would otherwise have been paid during the six-month
period but for the application of this provision, and the balance of the installments shall be payable in accordance with their original schedule. 

  
 9 

 (b) All in-kind benefits provided and expenses
eligible for reimbursement under this Agreement shall be provided by the Company or incurred by the Executive during the time periods set forth in this Agreement. All reimbursements shall be paid as soon as administratively practicable, but in no
event shall any reimbursement be paid after the last day of the taxable year following the taxable year in which the expense was incurred. The amount of in-kind benefits provided or reimbursable expenses
incurred in one taxable year shall not affect the in-kind benefits to be provided or the expenses eligible for reimbursement in any other taxable year (except for any lifetime or other aggregate limitation
applicable to medical expenses). Such right to reimbursement or in-kind benefits is not subject to liquidation or exchange for another benefit. 

(c) To the extent that any payment or benefit described in this Agreement constitutes
“non-qualified deferred compensation” under Section 409A of the Code, and to the extent that such payment or benefit is payable upon the Executive’s termination of employment, then such
payments or benefits shall be payable only upon the Executive’s “separation from service.” The determination of whether and when a separation from service has occurred shall be made in accordance with the presumptions set forth in
Treasury Regulation Section 1.409A-1(h). 
 (d) The parties intend that this Agreement will be
administered in accordance with Section 409A of the Code. To the extent that any provision of this Agreement is ambiguous as to its compliance with Section 409A of the Code, the provision shall be read in such a manner so that all payments
hereunder comply with Section 409A of the Code. Each payment pursuant to this Agreement is intended to constitute a separate payment for purposes of Treasury Regulation Section 1.409A-2(b)(2). The
parties agree that this Agreement may be amended, as reasonably requested by either party, and as may be necessary to fully comply with Section 409A of the Code and all related rules and regulations in order to preserve the payments and
benefits provided hereunder without additional cost to either party. 
 (e) The Company makes no representation or warranty and shall have no
liability to the Executive or any other person if any provisions of this Agreement are determined to constitute deferred compensation subject to Section 409A of the Code but do not satisfy an exemption from, or the conditions of, such Section.

 8. Continuing Obligations. 

(a) Restrictive Covenants Agreement. The Executive has previously entered into the Employee Invention and Non-Disclosure Agreement dated August 1, 2018, attached hereto as Exhibit A, and the Non-Competition and Non-Solicitation
Agreement dated August 1, 2018, attached hereto as Exhibit B (together, the “Restrictive Covenants Agreements”). The terms of the Restrictive Covenants Agreements continue to remain in full force and effect. For purposes of
this Agreement, the obligations in this Section 8 and those that arise in the Restrictive Covenants Agreements and any other agreement relating to confidentiality, assignment of inventions, or other restrictive covenants shall collectively be
referred to as the “Continuing Obligations.” 

  
 10 

 (b) Protected Disclosures and Other Protected Action. Nothing in this Agreement shall
be interpreted or applied to prohibit the Executive from making any good faith report to any governmental agency or other governmental entity (a “Government Agency”) concerning any act or omission that the Executive reasonably believes
constitutes a possible violation of federal or state law or making other disclosures that are protected under the anti-retaliation or whistleblower provisions of applicable federal or state law or regulation. In addition, nothing contained in this
Agreement limits the Executive’s ability to communicate with any Government Agency or otherwise participate in any investigation or proceeding that may be conducted by any Government Agency, including the Executive’s ability to provide
documents or other information, without notice to the Company. In addition, for the avoidance of doubt, pursuant to the federal Defend Trade Secrets Act of 2016, the Executive shall not be held criminally or civilly liable under any federal or state
trade secret law or under this Agreement or the Restrictive Covenants Agreements for the disclosure of a trade secret that (a) is made (i) in confidence to a federal, state, or local government official, either directly or indirectly, or
to an attorney; and (ii) solely for the purpose of reporting or investigating a suspected violation of law; or (b) is made in a complaint or other document filed in a lawsuit or other proceeding, if such filing is made under seal. 

9. Consent to Jurisdiction. The parties hereby consent to the jurisdiction of the state and federal courts of the Commonwealth of
Massachusetts. Accordingly, with respect to any such court action, the Executive (a) submits to the personal jurisdiction of such courts; (b) consents to service of process; and (c) waives any other requirement (whether imposed by
statute, rule of court, or otherwise) with respect to personal jurisdiction or service of process. 
 10. Integration. This
Agreement, along with the Restrictive Covenants Agreements, constitutes the entire agreement between the parties with respect to the subject matter hereof and supersedes all prior agreements between the parties concerning such subject matter,
including the Prior Agreement, provided that the Restrictive Covenants Agreement and the Equity Documents remain in full force and effect. 

11. Withholding; Tax Effect. All payments made by the Company to the Executive under this Agreement shall be net of any tax or other
amounts required to be withheld by the Company under applicable law. Nothing in this Agreement shall be construed to require the Company to make any payments to compensate the Executive for any adverse tax effect associated with any payments or
benefits or for any deduction or withholding from any payment or benefit. 
 12. Successor to the Executive. This Agreement shall
inure to the benefit of and be enforceable by the Executive’s personal representatives, executors, administrators, heirs, distributees, devisees and legatees. In the event of the Executive’s death after his termination of employment but
prior to the completion by the Company of all payments due him under this Agreement, the Company shall continue such payments to the Executive’s beneficiary designated in writing to the Company prior to his death (or to his estate, if the
Executive fails to make such designation). 

  
 11 

 13. Enforceability. If any portion or provision of this Agreement (including, without
limitation, any portion or provision of any section of this Agreement) shall to any extent be declared illegal or unenforceable by a court of competent jurisdiction, then the remainder of this Agreement, or the application of such portion or
provision in circumstances other than those as to which it is so declared illegal or unenforceable, shall not be affected thereby, and each portion and provision of this Agreement shall be valid and enforceable to the fullest extent permitted by
law. 
 14. Survival. The provisions of this Agreement shall survive the termination of this Agreement and/or the termination of the
Executive’s employment to the extent necessary to effectuate the terms contained herein. 
 15. Waiver. No waiver of any
provision hereof shall be effective unless made in writing and signed by the waiving party. The failure of any party to require the performance of any term or obligation of this Agreement, or the waiver by any party of any breach of this Agreement,
shall not prevent any subsequent enforcement of such term or obligation or be deemed a waiver of any subsequent breach. 
 16.
Notices. Any notices, requests, demands and other communications provided for by this Agreement shall be sufficient if in writing and delivered in person or sent by a nationally recognized overnight courier service or by registered or
certified mail, postage prepaid, return receipt requested, to the Executive at the last address the Executive has filed in writing with the Company or, in the case of the Company, at its main offices, attention of the Board. 

17. Amendment. This Agreement may be amended or modified only by a written instrument signed by the Executive and by a duly authorized
representative of the Company. 
 18. Effect on Other Plans and Agreements. An election by the Executive to resign for Good Reason
under the provisions of this Agreement shall not be deemed a voluntary termination of employment by the Executive for the purpose of interpreting the provisions of any of the Company’s benefit plans, programs or policies. Nothing in this
Agreement shall be construed to limit the rights of the Executive under the Company’s benefit plans, programs or policies except as otherwise provided in Section 8 hereof, and except that the Executive shall have no rights to any severance
benefits under any Company severance pay plan, offer letter or otherwise. In the event that the Executive is party to an agreement with the Company providing for payments or benefits under such agreement and this Agreement, the terms of this
Agreement shall govern and the Executive may receive payment under this Agreement only and not both. Further, Section 5 and Section 6 of this Agreement are mutually exclusive and in no event shall the Executive be entitled to payments or
benefits pursuant to Section 5 and Section 6 of this Agreement. 
 19. Governing Law. This is a Massachusetts contract and
shall be construed under and be governed in all respects by the laws of the Commonwealth of Massachusetts, without giving effect to the conflict of laws principles thereof. With respect to any disputes concerning federal law, such disputes shall be
determined in accordance with the law as it would be interpreted and applied by the United States Court of Appeals for the First Circuit. 

  
 12 

 20. Counterparts. This Agreement may be executed in any number of counterparts, each
of which when so executed and delivered shall be taken to be an original; but such counterparts shall together constitute one and the same document. 

21. Successor to Company. The Company shall require any successor (whether direct or indirect, by purchase, merger, consolidation or
otherwise) to all or substantially all of the business or assets of the Company expressly to assume and agree to perform this Agreement to the same extent that the Company would be required to perform it if no succession had taken place. Failure of
the Company to obtain an assumption of this Agreement at or prior to the effectiveness of any succession shall be a material breach of this Agreement. 

22. Gender Neutral. Wherever used herein, a pronoun in the masculine gender shall be considered as including the feminine gender unless
the context clearly indicates otherwise. 
 [Signature page follows.] 

  
 13 

 IN WITNESS WHEREOF, the parties have executed this Agreement effective on the date and year
first above written. 
  

			
	KARUNA THERAPEUTICS, INC.
		
	By:	 	          

	Its:	 	  

	
	EXECUTIVE
	
	  

	Steven Paul, M.D.

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