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  Exhibit 10.8    
    

 EMPLOYMENT AGREEMENT  

        THIS EMPLOYMENT AGREEMENT (the "Agreement"), made this 14th day of May 2008 (the "Effective Date"), is entered
into by Sepracor Inc., a Delaware corporation with its principal place of business at 84 Waterford Drive, Marlborough, Massachusetts 01752-7231(the "Company"), and
Mark H. N. Corrigan, residing at 389 Marlborough Street, Boston, MA 02115 (the "Executive"). 

        WHEREAS,
the Company desires to continue to employ the Executive and the Executive desires to continue to be employed by the Company; and 

        WHEREAS,
the Company has determined that appropriate steps should be taken to reinforce and encourage the continued employment of the Executive. 

        NOW
THEREFORE, in consideration of the mutual covenants and promises contained herein, and other good and valuable consideration, the receipt and sufficiency of which are hereby
acknowledged by the parties hereto, the parties agree as follows: 

        1.    Term of Employment.    The Company hereby agrees to continue to employ the Executive and the Executive hereby
agrees to continue to be employed by the Company, upon the terms set forth in this Agreement, until the fifth anniversary of the Effective Date (the "Term"). Notwithstanding the foregoing, the Term
shall be extended automatically without further action by either party by one (1) additional year (added to the end of the Term) on each succeeding anniversary of the Effective Date, unless
either party shall have served written notice upon the other party at least sixty (60) days preceding the date upon which such Term would end (such period, as it may be extended, the
"Employment Period"), unless sooner terminated in accordance with the provisions of Section 4. 

        2.    Title and Capacity.    The Executive shall serve as Executive Vice-President, Research and
Development of the Company. Executive shall report directly to the Chief Executive Officer of the Company and shall, except as permitted hereby, devote all of his business time and services to the
business and affairs of the Company. Executive shall also perform such other duties consistent with his position as Executive Vice-President, Research and Development as may be reasonably
assigned by the Chief Executive Officer and the Board of Directors of the Company (the "Board") from time to time. The Executive agrees to abide by the rules, regulations, instructions, personnel
practices and policies of the Company and any changes therein that may be adopted from time to time by the Company. 

        Notwithstanding
anything herein to the contrary, Executive shall be entitled to engage in (a) service on the board of directors of two companies, business or trade organizations
with prior Board approval, (b) service on the board of directors of not-for-profit or charitable organizations with prior Board approval, (c) other charitable
activities and community affairs and (d) managing his personal investments and affairs, in each case to the extent such activities do not materially interfere with the performance of his duties
and responsibilities to the Company. 

        3.    Compensation and Benefits.    

        3.1    Salary.    During the term of this Agreement, the Company agrees to continue to pay the Executive a base salary
at the annualized rate of $545,000 ("Base Salary"). The Base Salary shall be subject to annual review by the Board but shall not be reduced below $545,000 per annum. Such salary shall be payable to
Executive in bi-weekly installments and in accordance with the Company's normal payroll procedures. 

        3.2    Bonus.    The Executive shall be eligible for a performance-based annual bonus for each fiscal year of the Term
(the "Annual Bonus"). The Annual Bonus shall be based upon annual quantitative and qualitative performance targets as established by the Board in its sole discretion in accordance with the Company's
bonus plan; provided, that the Executive's annual bonus level 

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target
shall be set at fifty percent (50%) or more of Base Salary. The Annual Bonus is not earned until the close of business on the last business day of the Company's fiscal year. Any Annual Bonus
payable hereunder shall be payable, if at all, after the date of the delivery of the audited financial statements for the applicable fiscal year. 

        3.3    Benefits.    The Executive shall be entitled to participate in all bonus and benefit programs that the Company
establishes and makes available to its employees, to the extent that the Executive is eligible under (and subject to the provisions of) the plan documents governing those programs. The Executive shall
be entitled to no less than four weeks paid vacation per year, subject to the other terms of the Company's standard vacation policy (Schedule A). 

        3.4    Reimbursement of Expenses.    The Company shall reimburse the Executive for all reasonable travel (which shall
be deemed to include first class airfare), entertainment and other expenses incurred or paid by the Executive in connection with, or related to, the performance of his duties, responsibilities or
services under this Agreement, upon presentation by the Executive of documentation, expense statements, vouchers and/or such other supporting information as the Company may request. 

        3.5    Automobile.    The Company agrees to provide the Executive with an automobile allowance or a leased automobile
with a retail value of up to $60,000, which payments shall be made on a fully tax grossed-up basis. In addition, the Company agrees to pay all insurance, maintenance, fuel and other
customary costs associated with operating the automobile. 

        3.6    Withholding.    All salary, bonus and other compensation payable to the Executive shall be subject to
applicable withholding taxes. 

        4.    Employment Termination.    The employment of the Executive under this Agreement shall terminate upon the
occurrence of any of the following: 

        4.1   On
the expiration date of the Employment Period. 

        4.2   At
the election of the Company, for Cause (as defined below), immediately upon written notice by the Company to the Executive, which notice shall identify the Cause upon
which termination is based. For the purposes of this Section 4.2, Cause for termination shall mean: (a) the Executive's willful and continued failure to substantially perform his
reasonable assigned duties (other than any such failure resulting from incapacity due to physical or mental illness or any failure after the Executive gives notice of termination for Good Reason and
Good Reason exists), which failure is not cured within 30 days after a written demand for substantial performance is received by the Executive from the Board of Directors of the Company which
specifically identifies the manner in which the Board of Directors believes the Executive has not substantially performed the Executive's duties; (b) the Executive's willful engagement in
illegal conduct or gross misconduct which is materially and demonstrably injurious to the Company; or (c) a material breach of Section 6 or 7 of this Agreement by the Executive. For
purposes of this Section 4.2, no act or failure to act by the Executive shall be considered "willful" unless it is done, or omitted to be done, in bad faith and without reasonable belief that
the Executive's action or omission was in the best interests of the Company. 

        4.3   Upon
the death or disability of the Executive. As used in this Agreement, the term "disability" shall mean the Executive's absence from the full-time
performance of the Executive's duties with the Company for one hundred eighty (180) consecutive calendar days as a result of incapacity due to mental or physical illness which is determined to
be total and permanent by a physician selected by the Company or its insurers and acceptable to the Executive or the Executive's legal representative. 

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        4.4   At
the election of the Executive for Good Reason as defined herein. The Executive may terminate his employment for Good Reason at any time, following 30-days
prior written notice of such termination to the Company. Such notice shall provide factual details of the basis behind such termination and the Company shall have a thirty (30) day period
thereafter to cure such matter. As used herein, the term "Good Reason" shall mean: (a) a material breach by the Company of the terms of this Agreement, including the failure to pay Base Salary
or any Annual Bonus when due; or (b) any material adverse change by the Company in Executive's titles, authorities, duties, responsibilities or lines of reporting inconsistent with the terms
hereof or the assignment to Executive by the Company of titles, authorities, duties, responsibilities or lines of reporting inconsistent with the terms hereof, or (c) a relocation of the
principal offices of the Company to an area more than forty (40) miles from the location of such offices as of the date hereof. 

        4.5   At
the election of the Executive without Good Reason, upon not less than sixty (60) calendar days prior written notice of termination by the Executive to the
Company; provided, however, that the Company may, in its sole discretion, determine that the termination
of the Executive shall become effective immediately and in which case the termination shall still be considered at the election of the Executive without Good Reason. 

        4.6   At
the election of the Company, without Cause, upon not less than sixty (60) days written notice to Executive. 

        4.7   At
the election of the Company or the Executive in connection with a Change in Control, as set forth in the Executive Retention Agreement between the Company and the
Executive (the "ERA"), dated as of April 17, 2003. "Change in Control" shall have the meaning set forth in the ERA. 

        5.    Effect of Termination.    

        5.1    Non-Renewal, Termination Without Good Reason By the Executive or Termination For Cause By the
Company.    In the event the Executive's employment is terminated by non-renewal pursuant to Section 4.1, for Cause by the Company pursuant to
Section 4.2, or at the election of the Executive pursuant to Section 4.5, the Company shall pay to the Executive the compensation and benefits otherwise payable to him under
Section 3 through the last calendar day of his actual employment by the Company. 

        5.2    Termination for Death or Disability.    In the event the Executive's employment is terminated by death or
because of disability pursuant to Section 4.3, the Company shall pay to the estate of the Executive or to the Executive, as the case may be, (A) within thirty (30) days of the
date of the Executive's death or determination of disability, the compensation which would otherwise be payable to the Executive up to the end of the month in which the termination of his employment
because of death or disability occurs; and (B) an annual bonus, payable when bonuses are paid for that year, in an amount equal to the total bonus he would be paid for such year, if any,
multiplied by a fraction, the numerator of which is the number of days in the year that have elapsed since January 1 and the denominator of which is 365 (a "Pro Rata Bonus"). 

        5.3    Termination By the Executive With Good Reason or By the Company Without "Cause".    In the event the
Executive's employment is terminated by the Executive with Good Reason pursuant to Section 4.4 or by the Company without Cause pursuant to Section 4.6, the Company shall pay to the
Executive the compensation and benefits otherwise payable to him under Section 3 through the last calendar day of his actual employment by the Company. In addition, provided the Executive
executes and does not revoke a Separation Agreement and Release of Claims for the benefit of the Company substantially in the form set forth on Schedule B hereto, the Company shall
(a) continue to pay the Executive the Base Salary for eighteen (18) months in accordance with the Company's regular payroll practices; (b) pay the Executive a Pro Rata Bonus;
(c) pay the 

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Executive,
in bi-weekly installments, over an eighteen-month period, an amount equal in the aggregate to 1.5 times the average Annual Bonus earned for the two years prior to the date of
his termination; and (d) for 18 months following the date of his termination, allow the Executive to participate in the Company's executive retiree health benefit program based on the
same cost sharing arrangement that applied immediately prior to the date of his termination. 

        5.4    Termination Following a Change in Control.    In the event the Executive's employment is terminated pursuant to
Section 4.7 by the Company or by the Executive within 24 months following the Change in Control Date as defined in the ERA, the Executive will be entitled to the benefits set forth in
the ERA in accordance with the terms of the ERA. 

        5.5    Participation in Executive Retirement Health Benefit Program.    Following the date of the Executive's
termination and, if applicable, the 18 month period referred to in Section 5.3(d), for such time as the Executive elects to continue to participate in the Company's executive retiree
health benefit program, he will reimburse the Company at the lesser of (a) the actual cost to the Company of the employee's participation and (b) the rate applicable to former employees
of the Company to elect COBRA health coverage. 

        5.6    Payments Subject to Section 409A.    

        (a)   Subject
to this Section 5.6, payments or benefits under Section 5 shall begin only upon the date of a "separation from service" of the Executive
(determined as set forth below) which occurs on or after the termination of the Executive's employment. The following rules shall apply with respect to distribution of the payments and benefits, if
any, to be provided to the Executive under Section 5, as applicable: 

        (i)    It
is intended that each installment of the payments and benefits provided under Section 5 shall be treated as a separate "payment" for purposes of
Section 409A of the Code and the guidance issued thereunder ("Section 409A"). Neither the Company nor the Executive shall have the right to accelerate or defer the delivery of any such
payments or benefits except to the extent specifically permitted or required by Section 409A. 

        (ii)   If,
as of the date of the "separation from service" of the Executive from the Company, the Executive is not a "specified employee" (within the meaning of
Section 409A), then each installment of the payments and benefits shall be made on the dates and terms set forth in Section 5. 

        (iii)  If,
as of the date of the "separation from service" of the Executive from the Company, the Executive is a "specified employee" (within the meaning of
Section 409A), then: 

        (1)   Each
installment of the payments and benefits due under Section 5 that, in accordance with the dates and terms set forth herein, will in all circumstances,
regardless of when the separation from service occurs, be paid within the Short-Term Deferral Period (as hereinafter defined) shall be treated as a short-term deferral within
the meaning of Treasury Regulation Section 1.409A-1(b)(4) to the maximum extent permissible under Section 409A. For purposes of this Agreement, the "Short-Term
Deferral Period" means the period ending on the later of the 15th day of the third month following the end of the Executive's tax year in which the separation from service occurs
and the 15th day of the third month following the end of the Company's tax year in which the separation from service occurs; and 

        (2)   Each
installment of the payments and benefits due under Section 5 that is not described in Section 5.6 (a)(iii)(1) and that would, absent this subsection,
be paid within the six-month period following the "separation from service" of the Executive 

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from
the Company shall not be paid until the date that is six months and one day after such separation from service (or, if earlier, the Executive's death), with any such installments that are
required to be delayed being accumulated during the six-month period and paid in a lump sum on the date that is six months and one day following the Executive's separation from service and
any subsequent installments, if any, being paid in accordance with the dates and terms set forth herein; provided,  however, that the preceding provisions
of this sentence shall not apply to any installment of payments and benefits if and to the maximum extent that
that such installment is deemed to be paid under a separation pay plan that does not provide for a deferral of compensation by reason of the application of Treasury
Regulation 1.409A-1(b)(9)(iii) (relating to separation pay upon an involuntary separation from service). Any installments that qualify for the exception under Treasury Regulation
Section 1.409A-1(b)(9)(iii) must be paid no later than the last day of the Executive's second taxable year following his taxable year in which the separation from service occurs. 

        (b)   The
determination of whether and when a separation from service of the Executive from the Company has occurred shall be made and in a manner consistent with, and based
on the presumptions set forth in, Treasury Regulation Section 1.409A-1(h). Solely for purposes of this Section 5.6 (b), "Company" shall include all persons with whom the
Company would be considered a single employer under Section 414(b) and 414(c) of the Code. 

        (c)   All
reimbursements and in-kind benefits provided under the Agreement shall be made or provided in accordance with the requirements of Section 409A to
the extent that such reimbursements or in-kind benefits are subject to Section 409A. 

        6.    Non-Competition and Non-Solicitation.    

        (a)   While
the Executive is employed by the Company and for a period of twelve (12) months following the Executive's termination or cessation of such employment for
any reason, the Executive will not directly or indirectly: 

        (i)    Engage
in any business or enterprise (whether as an owner, partner, officer, employee, director, investor, lender, consultant, independent contractor or otherwise,
except as the holder of not more than 5% of the combined voting power of the outstanding stock of a publicly held company) that (A) is competitive with the Company's business and
(B) develops, designs, produces, markets, sells or renders any product or service competitive with any product developed, produced, marketed, sold or rendered by the Company while the Executive
was employed by the Company; 

        (ii)   Either
alone or in association with others, recruit or solicit, any person who was employed by the Company at any time during the period of the Executive's employment
with the Company, except for an individual whose employment with the Company has been terminated for a period of six months or longer; and 

        (iii)  Either
alone or in association with others, solicit, divert or take away, or attempt to divert or to take away, the business or patronage of any of the clients,
customers or accounts, or prospective clients, customers or accounts, of the Company which were contacted, solicited or served by the Executive while he was employed by the Company. 

        (b)   If
any restriction set forth in this Section 6 is found by any court of competent jurisdiction to be unenforceable because it extends for too long a period of
time or over too great a range of activities or in too broad a geographic area, it shall be interpreted to extend only over the maximum period of time, range of activities or geographic area as to
which it may be enforceable. 

5

 

 

        (c)   The
Executive acknowledges that the restrictions contained in this Agreement are necessary for the protection of the business and goodwill of the Company and are
considered by the Executive to be reasonable for such purpose. The Executive agrees that any breach of this Agreement will cause the Company substantial and irrevocable damage and therefore, in the
event of any such breach, in addition to such other remedies which may be available, the Company shall have the right to seek specific performance and injunctive relief without posting a bond. 

        (d)   The
geographic scope of this Section shall extend to anywhere the Company or any of its subsidiaries is doing business during the Term or has plans, during the Term, to
do business. 

        (e)   The
Executive agrees to provide a copy of this Agreement to all person and Entities with whom the Executive seeks to be hired or do business before accepting employment
or engagement with any of them. 

        (f)    If
the Executive violates the provisions of this Section, the Executive shall continue to be held by the restrictions set forth in this Section, until a period equal to
the period of restriction has expired without any violation. 

        7.    Proprietary Information and Developments.    

        7.1    Proprietary Information.    

        (a)   The
Executive agrees that all information, whether or not in writing, of a private, secret or confidential nature concerning the Company's business, business
relationships or financial affairs
(collectively, "Proprietary Information") is and shall be the exclusive property of the Company. By way of illustration, but not limitation, Proprietary Information may include discoveries,
inventions, products, product improvements, product enhancements, processes, methods, techniques, formulas, compositions, compounds, negotiation strategies and positions, projects, developments, plans
(including business and marketing plans), research data, clinical data, financial data (including sales, costs, profits and pricing methods), personnel data, computer programs (including software used
pursuant to a license agreement), customer and supplier lists, and contacts at or knowledge of customers or prospective customers of the Company. Except as required by applicable law, the Executive
will not disclose any Proprietary Information to any person or entity other than employees of the Company or use the same for any purposes (other than in the performance of his duties as an employee
of the Company) without prior written approval from the Chief Executive Officer, either during or after his employment with the Company, unless and until such Proprietary Information has become public
knowledge without fault by the Executive. 

        (b)   The
Executive agrees that all files, documents, letters, memoranda, reports, records, data, sketches, drawings, methods, laboratory notebooks, program listings, computer
equipment or devices, computer programs or other written, photographic, or other tangible material containing Proprietary Information, whether created by the Executive or others, which shall come into
his custody or possession, shall be and are the exclusive property of the Company and are to be used by the Executive only in the performance of his duties for the Company. All such materials or
copies thereof and all tangible property of the Company in the custody or possession of the Executive shall be delivered to the Company upon the earlier of (i) a request by the Company or
(ii) termination of his employment. After such delivery, the Executive shall not retain any such materials or copies thereof or any such tangible property. 

        (c)   The
Executive agrees that his obligation not to disclose or to use information and materials of the types set forth in subsections (a) and (b) above, and
his obligation to return materials and tangible property set forth in subsection (b) above, also extends to such types of information, materials and tangible property of customers of the
Company or suppliers to the 

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Company
or other third parties who may have disclosed or entrusted the same to the Company or to the Executive. 

        7.2    Developments.    

        (a)   The
Executive will make full and prompt disclosure to the Company of all inventions, creations, improvements, discoveries, trade secrets, secret processes, technology,
know-how, copyrightable materials, methods, developments, software, and works of authorship or other creative works, whether patentable or not, which are created, made, conceived or
reduced to practice by him or under his direction or jointly with others during his employment by the Company, whether or not during normal working hours or on the premises of the Company (all of
which are collectively referred to in this Agreement as "Developments"). 

        (b)   The
Executive agrees to assign and does hereby assign to the Company (or any person or entity designated by the Company) all his right, title and interest in and to all
Developments and all related patents, patent applications, copyrights and copyright applications. However, this subsection (b) shall not apply to Developments that do not relate to any business
or research and development conducted or planned to be conducted by the Company at the time such Development is created, made, conceived or reduced to practice and that are made and conceived by the
Executive not during normal working hours, not on the Company's premises and not using the Company's tools, devices, equipment or Proprietary Information. The Executive understands that, to the extent
this Agreement shall be construed in accordance with the laws of any state that precludes a requirement in an employee agreement to assign certain classes of inventions made by an employee, this
subsection (b) shall be interpreted not to apply to any invention that a court rules and/or the Company agrees falls within such classes. The Executive also hereby waives all claims to moral
rights in any Developments. 

        (c)   The
Executive agrees to cooperate fully with the Company and to take such further actions as may be necessary or desirable, both during and after his employment with the
Company, with respect to the procurement, maintenance and enforcement of copyrights, patents and other intellectual property rights (both in the United States and foreign countries) relating to
Developments. The Executive shall sign all papers, including, without limitation, copyright applications, patent applications, declarations, oaths, formal assignments, assignments of priority rights
and powers of attorney, that the Company may deem necessary or desirable in order to protect its rights and interests in any Development. The Executive further agrees that if the Company is unable,
after reasonable effort, to secure the signature of the Executive on any such papers, the Chief Executive Officer of the Company shall be entitled to execute any such papers as the agent and the
attorney-in-fact of the Executive, and the Executive hereby irrevocably designates and appoints the Chief Executive Officer of the Company as his agent and
attorney-in-fact to execute any such papers on his behalf and to take any and all actions as the Company may deem necessary or desirable in order to protect its rights and
interests in any Development under the conditions described in this sentence. 

        7.3    United States Government Obligations.    The Executive acknowledges that the Company from time to time may have
agreements with other parties or with the United States Government, or agencies thereof, which impose obligations or restrictions on the Company regarding inventions made during the course of work
under such agreements or regarding the confidential nature of such work. The Executive agrees to be bound by all such obligations and restrictions that are made known to the Executive and to take all
action necessary to discharge the obligations of the Company under such agreements. 

        7.4    Other Agreements.    The Executive hereby represents that he is not bound by the terms of any agreement with
any previous employer or other party to refrain from competing, directly or 

7

 

indirectly,
with the business of such previous employer or any other party. The Executive further represents that his performance of all the terms of this Agreement and the performance of his duties
as an employee of the Company does not and will not breach any agreement to keep in confidence proprietary information, knowledge or data acquired by him in confidence or in trust prior to his
employment with the Company and that the Executive will not disclose to the Company or induce the Company to use any confidential or proprietary information, knowledge or material belonging to any
previous employer or others. The Executive further represents that his performance of all the terms of this Agreement and the performance of his duties as an employee of the Company does not and will
not breach any agreement to refrain from soliciting employees, customers or suppliers of any former employer or others. 

        8.    Indemnification.    The Company shall indemnify the Executive in accordance with its Certificate of
Incorporation and By-Laws. 

        9.    Survival.    The provisions of Sections 6, 7 and 8 shall survive the termination of this Agreement for
any reason. 

        10.    Notices.    Any notices delivered under this Agreement shall be deemed duly delivered three (3) business
days after it is sent by registered or certified mail, return receipt requested, postage prepaid, or one (1) business day after it is sent for next-business day delivery via a
reputable nationwide overnight courier service, in each case to the address of the recipient set forth in the introductory paragraph hereto. Either party may change the address to which notices are to
be delivered by giving notice of such change to the other party in the manner set forth in this Section 10. 

        11.    Compliance with Code Section 409A.    This Agreement is intended to comply with the provisions of
Section 409A and the Agreement shall, to the extent practicable, be construed in accordance therewith. The Company makes no representation or warranty and shall have no liability to the
Executive or any other person if any provisions of this Agreement are determined to constitute deferred compensation subject to Section 409A and do not satisfy an exemption from, or the
conditions of, Section 409A. 

        12.    Pronouns.    Whenever the context may require, any pronouns used in this Agreement shall include the
corresponding masculine, feminine or neuter forms, and the singular forms of nouns and pronouns shall include the plural, and vice versa. 

        13.    Entire Agreement.    This Agreement, together with the ERA, constitutes the entire agreement between the
parties and supersedes all prior agreements and understandings, whether written or oral, relating to the subject matter of this Agreement, including the letter agreement between the Company and the
Executive dated March 11, 2003. 

        14.    Amendment.    This Agreement may be amended or modified only by a written instrument executed by both the
Company and the Executive. 

        15.    Governing Law.    This Agreement shall be governed by and construed in accordance with the laws of the
Commonwealth of Massachusetts (without reference to the conflict of laws provisions thereof). Any action, suit or other legal proceeding arising under or relating to any provision of this Agreement
shall be commenced only in a court of the Commonwealth of Massachusetts (or, if appropriate, a federal court located within the Commonwealth of Massachusetts), and the Company and the Executive each
consents to the jurisdiction of such a court. The Company and the Executive each hereby irrevocably waive any right to a trial by jury in any action, suit or other legal proceeding arising under or
relating to any provision of this Agreement or any other dealing between them relating to the subject matter of this transaction and the relationship that is being established. 

        16.    Successors and Assigns.    This Agreement shall be binding upon and inure to the benefit of both parties and
their respective successors and assigns, including any corporation with which or into 

8

 

which
the Company may be merged or which may succeed to its assets or business; provided, however, that
the obligations of the Executive are personal and shall not be assigned by him. 

        17.    Acknowledgment.    The Executive states and represents that he has had an opportunity to fully discuss and
review the terms of this Agreement with an attorney. The Executive further states and represents that he has carefully read this Agreement, understands the contents herein, freely and voluntarily
assents to all of the terms and conditions hereof, and signs his name of his own free act. 

        18.    Miscellaneous.    

        18.1 No
delay or omission by the Company in exercising any right under this Agreement shall operate as a waiver of that or any other right. A waiver or consent given by the
Company on any one occasion shall be effective only in that instance and shall not be construed as a bar to or waiver of any right on any other occasion. 

        18.2 The
captions of the sections of this Agreement are for convenience of reference only and in no way define, limit or affect the scope or substance of any section of this
Agreement. 

        18.3 In
case any provision of this Agreement shall be invalid, illegal or otherwise unenforceable, the validity, legality and enforceability of the remaining provisions
shall in no way be affected or impaired thereby. 

        IN
WITNESS WHEREOF, the parties hereto have executed this Agreement as of the day and year set forth above. 

					
	 	 	Sepracor Inc.
	

 	
 	

By:	
 	

/s/ ADRIAN ADAMS

	 	 	Title:	 	President and CEO

	

 	
 	

/s/ MARK H. N. CORRIGAN

Mark H. N. Corrigan

9

 
 

  SCHEDULE A    
    
    VACATION POLICY    
    

SEE ATTACHED POLICY

 

 
 

  SCHEDULE B    
    
    FORM OF SEPARATION AGREEMENT AND RELEASE OF CLAIMS    
    

        In connection with your separation from Sepracor Inc. (the "Company") on
[            ], and in order to receive the benefits as set forth in the Employment Agreement (the "Agreement") between you and the Company dated
[            ], 2008, this agreement must become binding between you and the Company. By signing and returning this agreement, you will be entering into a binding agreement
with the Company and will be agreeing to the terms and conditions set forth in the numbered paragraphs below, including the release of claims set forth in paragraph 1. Therefore, you are
advised to consult with an attorney before signing this agreement and you have been given more than twenty-one (21) days to do so. If you sign this agreement, you may change your
mind and revoke your agreement during the seven (7) day period after you have signed it. If you do not so revoke, this agreement will become a binding agreement between you and the Company upon
the expiration of the seven (7) day revocation period. 

        The
following numbered paragraphs set forth the terms and conditions which will apply if you timely sign and return this agreement and do not revoke it within the seven (7) day
revocation period: 

        1.     Release—In consideration of the payment of the severance benefits, which you acknowledge you would not
otherwise be entitled to receive, you hereby fully, forever, irrevocably and unconditionally release, remise and discharge the Company, its officers, directors, stockholders, corporate affiliates,
subsidiaries, parent companies, successors and assigns, agents and employees (each in their individual and corporate capacities) (hereinafter, the "Released Parties") from any and all claims, charges,
complaints, demands, actions, causes of action, suits, rights, debts, sums of money, costs, accounts, reckonings, covenants, contracts, agreements, promises, doings, omissions, damages, executions,
obligations, liabilities, and expenses (including attorneys' fees and costs), of every kind and nature which you ever had or now have against the Released Parties, including, but not limited to, those
claims arising out of your employment with and/or separation from the Company, including, but not limited to, all claims under Title VII of the Civil Rights Act of 1964, 42 U.S.C.
§ 2000e et seq., the Age Discrimination in Employment Act, 29 U.S.C. § 621 et
seq., the Americans With Disabilities Act of 1990, 42 U.S.C. § 12101 et seq., the Family and Medical Leave
Act, 29 U.S.C. § 2601 et seq., the Worker Adjustment and Retraining Notification Act ("WARN"), 29 U.S.C. § 2101  et seq.,
Section 806 of the Corporate and Criminal Fraud Accountability Act of 2002, 18 U.S.C. § 1514(A), the Rehabilitation
Act of 1973, 29 U.S.C. § 701 et seq., Executive Order 11246, Executive Order 11141, the Fair Credit Reporting Act, 15 U.S.C.
§ 1681 et seq., the Employee Retirement Income Security Act of 1974 ("ERISA"), 29 U.S.C. § 1001  et seq., the Massachusetts Fair
Employment Practices Act., M.G.L. c. 151B, § 1 et
seq., the Massachusetts Civil Rights Act, M.G.L. c. 12, §§ 11H and 11I, the Massachusetts Equal Rights Act, M.G.L. c. 93,
§ 102 and M.G.L. c. 214, § 1C, the Massachusetts Labor and Industries Act, M.G.L. c. 149, § 1 et
seq., the Massachusetts Privacy Act, M.G.L. c. 214, § 1B, and the Massachusetts Maternity Leave Act, M.G.L. c. 149, § 105D,
all as amended; all common law claims including, but not limited to, actions in tort, defamation and breach of contract; all claims to any non-vested ownership interest in the Company,
contractual or otherwise, including, but not limited to, claims to stock or stock options; and any claim or damage arising out of your employment with or separation from the Company (including a claim
for retaliation) under any common law theory or any federal, state or local statute or ordinance not expressly referenced above. Notwithstanding the foregoing, the release set forth in this
Section 1 shall not apply to (a) your rights under the Agreement, (b) any vested equity interest in the Company, including vested stock options or (c) the rights you have
to be indemnified and defended by the Company pursuant to the terms of the Company's Restated Certificate of Incorporation, as amended, or other organizing documents, and the rights that you have
under, or with respect to, the Company's Directors and Officers liability insurance policies with respect to conduct or events occurring during, or relating to, your employment by, or while serving as
an officer or director of, the Company, Without limiting the generality of the foregoing, the Company shall continue to cover you under its Directors and Officers liability insurance policies
following the 

1

 

Separation
Date in substantially the same amount and on substantially the same terms as the Company covers its other former officers and directors. 

        2.     On-Going Obligations—You acknowledge and reaffirm your obligation to keep confidential and not to
disclose any and all non-public information concerning the Company which you acquired during the course of your employment with the Company, including, but not limited to, any
non-public information concerning the Company's business affairs, business prospects and financial condition, as is stated more fully in the Non-Disclosure and Invention
Agreement, which you executed during or prior to your employment with the Company (the "Non-Disclosure Agreement"). You further acknowledge and reaffirm your obligations under the
Agreement for the benefit of the Company. 

        3.     Return of Company Property—You confirm that you have returned to the Company all keys,
files, records (and copies thereof), equipment (including, but not limited to, computer hardware, software and printers, wireless handheld devices, cellular phones, pagers, etc.), Company
identification, Company vehicles and any other Company owned property in your possession or control and have left intact all electronic Company documents, including but not limited to, those that you
developed or helped develop during your employment. You further confirm that you have cancelled all accounts for your benefit, if any, in the Company's name, including but not limited to, credit
cards, telephone charge cards, cellular phone and/or pager accounts and computer accounts. 

        4.     Business Expenses and Compensation—You acknowledge that you have been reimbursed by the Company for all
business expenses incurred in conjunction with your employment with the Company and that no other reimbursements are owed to you. You further acknowledge that you have received payment in full for all
services rendered in conjunction with your employment by the Company and that no other compensation is owed to you except as provided in the Agreement. 

        5.     Non-Disparagement—You understand and agree that, as a condition for payment to you of the
consideration herein described and described in the Agreement, you shall not make any false, disparaging or derogatory statements to any media outlet, industry group, financial institution or current
or former employee, consultant, client or customer of the Company regarding the Company or any of its directors, officers, employees, agents or representatives or about the Company's business affairs
and financial condition; provided, however, that nothing herein shall prevent you from making truthful
disclosures to any governmental entity or in any litigation or arbitration. The Company agrees not to make any false, disparaging or derogatory statements about you to any media outlet, industry
group, financial institution, or current or former employee, consultant, client, or customer; provided,  however, that nothing herein shall prevent the
Company from making truthful disclosures to any governmental entity or in any litigation or arbitration.
In the event that any inquiries are directed to the Company's Human Resources Office regarding you from prospective employers, the Company will explain its neutral reference policy, confirm only the
fact of your former employment with the Company, starting and ending dates, and your job title in the last position held. 

        6.     Amendment—This agreement shall be binding upon the parties and may not be modified in any manner, except by an
instrument in writing of concurrent or subsequent date signed by duly authorized representatives of the parties hereto. This agreement is binding upon and shall inure to the benefit of the parties and
their respective agents, assigns, heirs, executors, successors and administrators. 

        7.     Waiver of Rights—No delay or omission by the Company or you in exercising any right under this agreement shall
operate as a waiver of that or any other right. A waiver or consent given by the Company or you on any one occasion shall be effective only in that instance and shall not be construed as a bar or
waiver of any right on any other occasion. 

        8.     Validity—Should any provision of this agreement be declared or be determined by any court of competent
jurisdiction to be illegal or invalid, the validity of the remaining parts, terms or provisions shall not be affected thereby and said illegal or invalid part, term or provision shall be deemed not to
be a part of this agreement. 

2

 

        9.     Tax Provision—In connection with the severance benefits provided to you pursuant to this agreement and the
Agreement, the Company shall withhold and remit to the tax authorities the amounts required under applicable law, and you shall be responsible for all applicable taxes with respect to such severance
benefits under applicable law. You acknowledge that you are not relying upon advice or representation of the Company with respect to the tax treatment of any of the severance benefits. 

        10.   Nature of Agreement—You understand and agree that this agreement, together with the Agreement, is a severance
agreement and does not constitute an admission of liability or wrongdoing on the part of the Company. 

        11.   Acknowledgments—You acknowledge that you have been given at least twenty-one (21) days to
consider this agreement and that the Company advised you to consult with an attorney of your own choosing prior to signing this agreement. You understand that you may revoke this agreement for a
period of seven (7) days after you sign this agreement, and the agreement shall not be effective or enforceable until the expiration of this seven (7) day revocation period.  You understand and agree that by entering
into this agreement you are waiving any and all rights or claims you might have under The Age Discrimination in Employment Act, as
amended by The Older Workers Benefit Protection Act, and that you have received consideration beyond that to which you were previously entitled.

        12.   Voluntary Assent—You affirm that, other than as contained in the Agreement, no other promises or agreements
of any kind have been made to or with you by any person or entity whatsoever to cause you to sign this agreement, and that you fully understand the meaning and intent of this agreement. You state and
represent that you have had an opportunity to fully discuss and review the terms of this agreement with an attorney. You further state and represent that you have carefully read this agreement,
understand the contents herein, freely and voluntarily assent to all of the terms and conditions hereof, and sign your name of your own free act. 

        13.   Applicable Law—This agreement shall be interpreted and construed by the laws of the Commonwealth of
Massachusetts, without regard to conflict of laws provisions. You hereby irrevocably submit to and acknowledge and recognize the jurisdiction of the courts of the Commonwealth of Massachusetts, or if
appropriate, a federal court located in Massachusetts (which courts, for purposes of this agreement, are the only courts of competent jurisdiction), over any suit, action or other proceeding arising
out of, under or in connection with this agreement or the subject matter hereof. 

        14.   Entire Agreement—This agreement, together with the Agreement, contains and constitutes the entire
understanding and agreement between the parties hereto with respect to your severance benefits and the settlement of claims against the Company and cancels all previous oral and written negotiations,
agreements, commitments and writings in connection therewith. Nothing in this paragraph, however, shall modify, cancel or supersede your obligations set forth in paragraph 2 herein. 

							
	 	 	Sepracor Inc.	 	 
	

 	
 	

By:	
 	

 

	
 	

 
	 	 	Name:

Title:

	 	 

        I
hereby agree to the terms and conditions set forth above. I have been given at least twenty-one (21) days to consider this agreement and I have chosen to execute
this on the date below. I intend that this agreement become a binding agreement between me and the Company if I do not revoke my acceptance in seven (7) days by
notifying                                    in
writing. 

					
	 	 	 	 	 
	 	 	Date	 	 
	

Name	 	 	 	

 

3

QuickLinks

Exhibit 10.8

SCHEDULE A VACATION POLICY

SCHEDULE B FORM OF SEPARATION AGREEMENT AND RELEASE OF CLAIMSQuickLinks
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  Exhibit 10.9    
    

 SEPRACOR INC.  

 2000 STOCK INCENTIVE PLAN

1.     Purpose

        The
purpose of this 2000 Stock Incentive Plan (the "Plan") of Sepracor Inc., a Delaware corporation (the "Company"), is to advance the interests of the Company's stockholders by
enhancing the Company's ability to attract, retain and motivate persons who make (or are expected to make) important contributions to the Company by providing such persons with equity ownership
opportunities
and performance-based incentives and thereby better aligning the interests of such persons with those of the Company's stockholders. Except where the context otherwise requires, the term "Company"
shall include any of the Company's present or future subsidiary corporations as defined in Section 424(f) of the Internal Revenue Code of 1986, as amended, and any regulations promulgated
thereunder (the "Code") and any other business venture (including, without limitation, joint venture or limited liability company) in which the Company has a significant interest, as determined by the
Board of Directors of the Company (the "Board"). 

2.     Eligibility

        All
of the Company's employees, officers, directors, consultants and advisors (and any individuals who have accepted an offer for employment) are eligible to be granted options,
restricted stock awards, or other stock-based awards (each, an "Award") under the Plan. Each person who has been granted an Award under the Plan shall be deemed a "Participant". 

3.     Administration, Delegation

        (a)    Administration by Board of Directors.    The Plan will be administered by the Board. The Board shall have
authority to grant Awards and to adopt, amend and repeal such administrative rules, guidelines and practices relating to the Plan as it shall deem advisable. The Board may correct any defect, supply
any omission or reconcile any inconsistency in the Plan or any Award in the manner and to the extent it shall deem expedient to carry the Plan into effect and it shall be the sole and final judge of
such expediency. All decisions by the Board shall be made in the Board's sole discretion and shall be final and binding on all persons having or claiming any interest in the Plan or in any Award. No
director or person acting pursuant to the authority delegated by the Board shall be liable for any action or determination relating to or under the Plan made in good faith. 

        (b)    Appointment of Committees.    To the extent permitted by applicable law, the Board may delegate any or all of
its powers under the Plan to one or more committees or subcommittees of the Board (a "Committee"). All references in the Plan to the "Board" shall mean the Board or a Committee of the Board referred
to in Section 3(b) to the extent that the Board's powers or authority under the Plan have been delegated to such Committee. 

4.     Stock Available for Awards

        (a)    Number of Shares.    Subject to adjustment under Section 8, Awards may be made under the Plan for up to
2,500,000 shares of common stock, $.10 par value per share, of the Company (the "Common Stock"). If any Award expires or is terminated, surrendered or canceled without having been fully exercised or
is forfeited in whole or in part or results in any Common Stock not being issued, the unused Common Stock covered by such Award shall again be available for the grant of Awards under the Plan,
subject, however, in the case of Incentive Stock Options (as hereinafter defined), to any 

1

 

limitation
required under the Code. Shares issued under the Plan may consist in whole or in part of authorized but unissued shares or treasury shares. 

        (b)    Per-Participant Limit.    Subject to adjustment under Section 8, for Awards granted after
the Common Stock is registered under the Securities Exchange Act of 1934 (the "Exchange Act"), the maximum number of shares of Common Stock with respect to which Awards may be granted to any
Participant under the Plan shall be 500,000 per calendar year. The per-Participant limit described in this Section 4(b) shall be construed and applied consistently with
Section 162(m) of the Code ("Section 162(m)"). 

5.     Stock Options

        (a)    General.    The Board may grant options to purchase Common Stock (each, an "Option") and determine the number
of shares of Common Stock to be covered by each Option, the exercise price of each Option and the conditions and limitations applicable to the exercise of each Option, including conditions relating to
applicable federal or state securities laws, as it considers necessary or advisable. An Option which is not intended to be an Incentive Stock Option (as hereinafter defined) shall be designated a
"Nonstatutory Stock Option". 

        (b)    Incentive Stock Options.    An Option that the Board intends to be an "incentive stock option" as defined in
Section 422 of the Code (an "Incentive Stock Option") shall only be granted to employees of the Company and shall be subject to and shall be construed consistently with the requirements of
Section 422 of the Code. The Company shall have no liability to a Participant, or any other party, if an Option (or any part thereof) which is intended to be an Incentive Stock Option is not an
Incentive Stock Option. 

        (c)    Exercise Price.    The Board shall establish the exercise price at the time each Option is granted and specify
it in the applicable option agreement, provided, however, that the exercise price shall not be
less than 100% of the fair market value of the Common Stock, as determined by the Board, at the time the Option is granted. 

        (d)    Duration of Options.    Each Option shall be exercisable at such times and subject to such terms and conditions
as the Board may specify in the applicable option agreement, provided however, that no Option will be granted for a term in excess of ten years. 

        (e)    Exercise of Option.    Options may be exercised by delivery to the Company of a written notice of exercise
signed by the proper person or by any other form of notice (including electronic notice) approved by the Board together with payment in full as specified in Section 5(f) for the number of
shares for which the Option is exercised. 

        (f)    Payment Upon Exercise.    Common Stock purchased upon the exercise of an Option granted under the Plan shall be
paid for as follows: 

        (1)   in
cash or by check, payable to the order of the Company; 

        (2)   except
as the Board may, in its sole discretion, otherwise provide in an option agreement, by (i) delivery of an irrevocable and unconditional undertaking by a
creditworthy broker to deliver promptly to the Company sufficient funds to pay the exercise price or (ii) delivery by the Participant to the Company of a copy of irrevocable and unconditional
instructions to a creditworthy broker to deliver promptly to the Company cash or a check sufficient to pay the exercise price; 

        (3)   when
the Common Stock is registered under the Exchange Act, by delivery of shares of Common Stock owned by the Participant valued at their fair market value as
determined by (or in a manner approved by) the Board in good faith ("Fair Market Value"), provided (i) such method 

2

 

of
payment is then permitted under applicable law and (ii) such Common Stock was owned by the Participant at least six months prior to such delivery; 

        (4)   to
the extent permitted by the Board, in its sole discretion by (i) delivery of a promissory note of the Participant to the Company on terms determined by the
Board, or (ii) payment of such other lawful consideration as the Board may determine; or 

        (5)   by
any combination of the above permitted forms of payment. 

        (g)    Substitute Options.    In connection with a merger or consolidation of an entity with the Company or the
acquisition by the Company of property or stock of an entity, the Board may grant Options in substitution for any options or other stock or stock-based awards granted by such entity or an affiliate
thereof. Substitute Options may be granted on such terms as the Board deems appropriate in the circumstances, notwithstanding any limitations on Options contained in the other sections of this
Section 5. 

6.     Restricted Stock

        (a)    Grants.    The Board may grant Awards entitling recipients to acquire shares of Common Stock, subject to the
right of the Company to repurchase all or part of such shares at their issue price or other stated or formula price (or to require forfeiture of such shares if issued at no cost) from the recipient in
the event that conditions specified by the Board in the applicable Award are not satisfied prior to the end of the applicable restriction period or periods established by the Board for such Award
(each, a "Restricted Stock Award"). 

        (b)    Terms and Conditions.    The Board shall determine the terms and conditions of any such Restricted Stock Award,
including the conditions for repurchase (or forfeiture) and the issue price, if any. Any stock certificates issued in respect of a Restricted Stock Award shall be registered in the name of the
Participant and, unless otherwise determined by the Board, deposited by the Participant, together with a stock power endorsed in blank, with the Company (or its designee). At the expiration of the
applicable restriction periods, the Company (or such designee) shall deliver the certificates no longer subject to such restrictions to the Participant or if the Participant has died, to the
beneficiary designated, in a manner determined by the Board, by a Participant to receive amounts due or exercise rights of the Participant in the event of the Participant's death (the "Designated
Beneficiary"). In the absence of an effective designation by a Participant, Designated Beneficiary shall mean the Participant's estate. 

7.     Other Stock-Based Awards

        The
Board shall have the right to grant other Awards based upon the Common Stock having such terms and conditions as the Board may determine, including the grant of shares based upon
certain conditions, the grant of securities convertible into Common Stock and the grant of stock appreciation rights. 

8.     Adjustments for Changes in Common Stock and Certain Other Events

        (a)    Changes in Capitalization.    In the event of any stock split, reverse stock split, stock dividend,
recapitalization, combination of shares, reclassification of shares, spin-off or other similar change in capitalization or event, or any distribution to holders of Common Stock other than
a normal cash dividend, (i) the number and class of securities available under this Plan, (ii) the per-Participant limit set forth in Section 4(b), (iii) the
number and class of securities and exercise price per share subject to each outstanding Option, (iv) the repurchase price per share subject to each outstanding Restricted Stock Award, and
(v) the terms of each other outstanding Award shall be appropriately adjusted by the Company (or substituted Awards may be made, if applicable) to the extent the Board shall determine, in good
faith, that such an adjustment (or substitution) is necessary and appropriate. If this Section 8(a) applies and Section 8(c) also applies to any event, Section 8(c) shall be
applicable to such event, and this Section 8(a) shall not be applicable. 

3

 

  
        (b)    Liquidation or Dissolution.    In the event of a proposed liquidation or dissolution of the Company, the
Board
shall upon written notice to the Participants provide that all then unexercised Options will (i) become exercisable in full as of a specified time at least 10 business days prior to the
effective date of such liquidation or dissolution and (ii) terminate effective upon such liquidation or dissolution, except to the extent exercised before such effective date. The Board may
specify the effect of a liquidation or dissolution on any Restricted Stock Award or other Award granted under the Plan at the time of the grant of such Award. 

        (c)    Acquisition and Change in Control Events    

        (1)    Definitions    

        (a)   An
"Acquisition Event" shall mean: 

	(i)
	any
merger or consolidation of the Company with or into another entity as a result of which the Common Stock is converted into or exchanged for the right to
receive cash, securities or other property; or

	(ii)
	any
exchange of shares of the Company for cash, securities or other property pursuant to a statutory share exchange transaction. 

        (b)   A
"Change in Control Event" shall mean: 

	(i)
	the
acquisition by an individual, entity or group (within the meaning of Section 13(d)(3) or 14(d)(2) of the Securities Exchange Act of 1934, as
amended (the "Exchange Act")) (a "Person") of beneficial ownership of any capital stock of the Company if, after such acquisition, such Person beneficially owns (within the meaning of
Rule 13d-3 promulgated under the Exchange Act) 30% or more of either (x) the then-outstanding shares of common stock of the Company (the "Outstanding Company
Common Stock") or (y) the combined voting power of the then-outstanding securities of the Company entitled to vote generally in the election of directors (the "Outstanding Company
Voting Securities"); provided, however, that for purposes of this subsection (i), the following
acquisitions shall not constitute a Change in Control Event: (A) any acquisition directly from the Company (excluding an acquisition pursuant to the exercise, conversion or exchange of any
security exercisable for, convertible into or exchangeable for common stock or voting securities of the Company, unless the Person exercising, converting or exchanging such security acquired such
security directly from the Company or an underwriter or agent of the Company), (B) any acquisition by any employee benefit plan (or related trust) sponsored or maintained by the Company or any
corporation controlled by the Company, or (C) any acquisition by any corporation pursuant to a Business Combination (as defined below) which complies with clauses (x) and (y) of
subsection (iii) of this definition; or

	(ii)
	such
time as the Continuing Directors (as defined below) do not constitute a majority of the Board (or, if applicable, the Board of Directors of a
successor corporation to the Company), where the term "Continuing Director" means at any date a member of the Board (x) who was a member of the Board on the date of the initial adoption of this
Plan by the Board or (y) who was nominated or elected subsequent to such date by at least a majority of the directors who were Continuing Directors at the time of such nomination or election or
whose election to the Board was recommended or endorsed by at least a majority of the directors who were Continuing Directors at the time of such nomination or election;  provided, however, that there shall be excluded from this clause (y) any individual whose initial
assumption of office occurred as a result of an actual or 

4

 

threatened
election contest with respect to the election or removal of directors or other actual or threatened solicitation of proxies or consents, by or on behalf of a person other than the Board; or 

	(iii)
	the
consummation of a merger, consolidation, reorganization, recapitalization or statutory share exchange involving the Company or a sale or other
disposition of all or substantially all of the assets of the Company (a "Business Combination"), unless, immediately following such Business Combination, each of the following two conditions is
satisfied: (x) all or substantially all of the individuals and entities who were the beneficial owners of the Outstanding Company Common Stock and Outstanding Company Voting Securities
immediately prior to such Business Combination beneficially own, directly or indirectly, more than 50% of the then-outstanding shares of common stock and the combined voting power of the
then-outstanding securities entitled to vote generally in the election of directors, respectively, of the resulting or acquiring corporation in such Business Combination (which shall
include, without limitation, a corporation which as a result of such transaction owns the Company or substantially all of the Company's assets either directly or through one or more subsidiaries)
(such resulting or acquiring corporation is referred to herein as the "Acquiring Corporation") in substantially the same proportions as their ownership of the Outstanding Company Common Stock and
Outstanding Company Voting Securities, respectively, immediately prior to such Business Combination and (y) no Person (excluding the Acquiring Corporation or any employee benefit plan (or
related trust) maintained or sponsored by the Company or by the Acquiring Corporation) beneficially owns, directly or indirectly, 30% or more of the then-outstanding shares of common stock
of the Acquiring Corporation, or of the combined voting power of the then-outstanding securities of such corporation entitled to vote generally in the election of directors (except to the
extent that such ownership existed prior to the Business Combination). 

        (2)    Effect on Options    

	(a)
	Acquisition Event.    Upon the occurrence of an Acquisition Event (regardless of whether such
event also constitutes a Change in Control Event), or the execution by the Company of any agreement with respect to an Acquisition Event (regardless of whether such event will result in a Change in
Control Event), the Board shall provide that all outstanding Options shall be assumed, or equivalent options shall be substituted, by the acquiring or succeeding corporation (or an affiliate thereof);  provided
that if such Acquisition Event also constitutes a Change in Control Event, except to the extent specifically provided to the contrary in the
instrument evidencing any Option or any other agreement between a Participant and the Company, such assumed or substituted options shall be immediately exercisable in full upon the occurrence of such
Acquisition Event. For purposes hereof, an Option shall be considered to be assumed if, following consummation of the Acquisition Event, the Option confers the right to purchase, for each share of
Common Stock subject to the Option immediately prior to the consummation of the Acquisition Event, the consideration (whether cash, securities or other property) received as a result of the
Acquisition Event by holders of Common Stock for each share of Common Stock held immediately prior to the consummation of the Acquisition Event (and if holders were offered a choice of consideration,
the type of consideration chosen by the holders of a majority of the outstanding shares of Common Stock); provided, however, that if the consideration received as a result of the Acquisition Event is
not 

5

 

solely
common stock of the acquiring or succeeding corporation (or an affiliate thereof), the Company may, with the consent of the acquiring or succeeding corporation, provide for the consideration to
be received upon the exercise of Options to consist solely of common stock of the acquiring or succeeding corporation (or an affiliate thereof) equivalent in fair market value to the per share
consideration received by holders of outstanding shares of Common Stock as a result of the Acquisition Event. 

        Notwithstanding
the foregoing, if the acquiring or succeeding corporation (or an affiliate thereof) does not agree to assume, or substitute for, such Options, then the Board shall, upon
written notice to the Participants, provide that all then unexercised Options will become exercisable in full as of a specified time prior to the Acquisition Event and will terminate immediately prior
to the consummation of such Acquisition Event, except to the extent exercised by the Participants before the consummation of such Acquisition Event; provided, however, in the event of an Acquisition
Event under the terms of which holders of Common Stock will receive upon consummation thereof a cash payment for each share of Common Stock surrendered pursuant to such Acquisition Event (the
"Acquisition Price"), then the Board may instead provide that all outstanding Options shall terminate upon consummation of such Acquisition Event and that each Participant shall receive, in exchange
therefor, a cash payment equal to the amount (if any) by which (A) the Acquisition Price multiplied by the number of shares of Common Stock subject to such outstanding Options (whether or not
then exercisable), exceeds (B) the aggregate exercise price of such Options.  

	(b)
	Change in Control Event that is not an Acquisition Event.    Upon the occurrence of a Change in
Control Event that does not also constitute an Acquisition Event, except to the extent specifically provided to the contrary in the instrument evidencing any Option or any other agreement between a
Participant and the Company, all Options then-outstanding shall automatically become immediately exercisable in full. 

        (3)    Effect on Restricted Stock Awards    

	(a)
	Acquisition Event that is not a Change in Control Event.    Upon the occurrence of an Acquisition
Event that is not a Change in Control Event, the repurchase and other rights of the Company under each outstanding Restricted Stock Award shall inure to the benefit of the Company's successor and
shall apply to the cash, securities or other property which the Common Stock was converted into or exchanged for pursuant to such Acquisition Event in the same manner and to the same extent as they
applied to the Common Stock subject to such Restricted Stock Award. 

6

 

	(b)
	Change in Control Event.    Upon the occurrence of a Change in Control Event (regardless of
whether such event also constitutes an Acquisition Event), except to the extent specifically provided to the contrary in the instrument evidencing any Restricted Stock Award or any other agreement
between a Participant and the Company, all restrictions and conditions on all Restricted Stock Awards then-outstanding shall automatically be deemed terminated or satisfied. 

        (4)    Effect on Other Awards    

	(a)
	Acquisition Event that is not a Change in Control Event.    The Board shall specify the effect of
an Acquisition Event that is not a Change in Control Event on any other Award granted under the Plan at the time of the grant of such Award.

	(b)
	Change in Control Event.    Upon the occurrence of a Change in Control Event (regardless of
whether such event also constitutes an Acquisition Event), except to the extent specifically provided to the contrary in the instrument evidencing any other Award or any other agreement between a
Participant and the Company, all other Awards shall become exercisable, realizable or vested in full, or shall be free of all conditions or restrictions, as applicable to each such Award. 

        (5)    Limitations.    Notwithstanding the foregoing provisions of this Section 8(c), if the Change in Control
Event is intended to be accounted for as a "pooling of interests" for financial accounting purposes, and if the acceleration to be effected by the foregoing provisions of this Section 8(c)
would preclude accounting for the Change in Control Event as a "pooling of interests" for financial accounting purposes, then no such acceleration shall occur upon the Change in Control Event. 

9.     General Provisions Applicable to Awards

        (a)    Transferability of Awards.    Except as the Board may otherwise determine or provide in an Award, Awards shall
not be sold, assigned, transferred, pledged or otherwise encumbered by the person to whom they are granted, either voluntarily or by operation of law, except by will or the laws of descent and
distribution, and, during the life of the Participant, shall be exercisable only by the Participant. References to a Participant, to the extent relevant in the context, shall include references to
authorized transferees. 

        (b)    Documentation.    Each Award shall be evidenced by a written instrument in such form as the Board shall
determine. Each Award may contain terms and conditions in addition to those set forth in the Plan. 

        (c)    Board Discretion.    Except as otherwise provided by the Plan, each Award may be made alone or in addition or
in relation to any other Award. The terms of each Award need not be identical, and the Board need not treat Participants uniformly. 

        (d)    Termination of Status.    The Board shall determine the effect on an Award of the disability, death,
retirement, authorized leave of absence or other change in the employment or other status of a Participant and the extent to which, and the period during which, the Participant, the Participant's
legal representative, conservator, guardian or Designated Beneficiary may exercise rights under the Award. 

        (e)    Withholding.    Each Participant shall pay to the Company, or make provision satisfactory to the Board for
payment of, any taxes required by law to be withheld in connection with Awards to such Participant no later than the date of the event creating the tax liability. Except as the Board may otherwise
provide in an Award, when the Common Stock is registered under the Exchange Act, Participants may, to the extent then permitted under applicable law, satisfy such tax obligations in whole or in part
by delivery of shares of Common Stock, including shares retained from the Award 

7

 

creating
the tax obligation, valued at their Fair Market Value. The Company may, to the extent permitted by law, deduct any such tax obligations from any payment of any kind otherwise due to a
Participant. 

        (f)    Amendment of Award.    The Board may amend, modify or terminate any outstanding Award, including but not
limited to, substituting therefor another Award of the same or a different type, changing the date of exercise or realization, and converting an Incentive Stock Option to a Nonstatutory Stock Option,
provided that the Participant's consent to such action shall be required unless the Board determines that the action, taking into account any related action, would not materially and adversely affect
the Participant. 

        (g)    Conditions on Delivery of Stock.    The Company will not be obligated to deliver any shares of Common Stock
pursuant to the Plan or to remove restrictions from shares previously delivered under the Plan until (i) all conditions of the Award have been met or removed to the satisfaction of the Company,
(ii) in the opinion of the Company's counsel, all other legal matters in connection with the issuance and delivery of such shares have been satisfied, including any applicable securities laws
and any applicable stock exchange or stock market rules and regulations, and (iii) the Participant has executed and delivered to the Company such representations or agreements as the Company
may consider appropriate to satisfy the requirements of any applicable laws, rules or regulations. 

        (h)    Acceleration.    The Board may at any time provide that any Options shall become immediately exercisable in
full or in part, that any Restricted Stock Awards shall be free of restrictions in full or in part or that any other Awards may become exercisable in full or in part or free of some or all
restrictions or conditions, or otherwise realizable in full or in part, as the case may be. 

10.   Miscellaneous

        (a)    No Right To Employment or Other Status.    No person shall have any claim or right to be granted an Award, and
the grant of an Award shall not be construed as giving a Participant the right to continued employment or any other relationship with the Company. The Company expressly reserves the right at
any time to dismiss or otherwise terminate its relationship with a Participant free from any liability or claim under the Plan, except as expressly provided in the applicable Award. 

        (b)    No Rights As Stockholder.    Subject to the provisions of the applicable Award, no Participant or Designated
Beneficiary shall have any rights as a stockholder with respect to any shares of Common Stock to be distributed with respect to an Award until becoming the record holder of such shares.
Notwithstanding the foregoing, in the event the Company effects a split of the Common Stock by means of a stock dividend and the exercise price of and the number of shares subject to such Option are
adjusted as of the date of the distribution of the dividend (rather than as of the record date for such dividend), then an optionee who exercises an Option between the record date and the distribution
date for such stock dividend shall be entitled to receive, on the distribution date, the stock dividend with respect to the shares of Common Stock acquired upon such Option exercise, notwithstanding
the fact that such shares were not outstanding as of the close of business on the record date for such stock dividend. 

        (c)    Effective Date and Term of Plan.    The Plan shall become effective on the date on which it is adopted by the
Board, but no Award granted to a Participant that is intended to comply with Section 162(m) shall become exercisable, vested or realizable, as applicable to such Award, unless and until the
Plan has been approved by the Company's stockholders to the extent stockholder approval is required by Section 162(m) in the manner required under Section 162(m) (including the vote
required under Section 162(m)). No Awards shall be granted under the Plan after the completion of ten years from the earlier of (i) the date on which the Plan was adopted by the Board or
(ii) the date the Plan was approved by the Company's stockholders, but Awards previously granted may extend beyond that date. 

8

 

        (d)    Amendment of Plan.    The Board may amend, suspend or terminate the Plan or any portion thereof at any time,
provided that to the extent required by Section 162(m), no Award granted to a Participant that is intended to comply with Section 162(m) after the date of such amendment shall become
exercisable, realizable or vested, as applicable to such Award, unless and until such amendment shall have been approved by the Company's stockholders as required by Section 162(m) (including
the vote required under Section 162(m)). 

        (e)    Governing Law.    The provisions of the Plan and all Awards made hereunder shall be governed by and interpreted
in accordance with the laws of the State of Delaware, without regard to any applicable conflicts of law. 

Adopted
by the Board of Directors on February 24, 2000 

Adopted
by the Stockholders on May 24, 2000 

9

 

   AMENDMENT NO 1. TO

2000 STOCK INCENTIVE PLAN

OF

SEPRACOR INC.  

        The 2000 Stock Incentive Plan (the "Plan") of Sepracor Inc. be, and hereby is, amended as follows: 

        1.     Section 4,
paragraph (a) is deleted in its entirety and the following is substituted in its place: 

        "(a)    Number of Shares.    Subject to adjustment under Section 8, Awards may be made under the Plan for up to
4,000,000 shares of common stock, $.10 par value per share, of the Company (the "Common Stock"). If any Award expires or is terminated, surrendered or cancelled without having been fully exercised or
is forfeited in whole or in part or results in any Common Stock not being issued, the unused Common Stock covered by such Award shall again be available for the grant of Awards under the Plan,
subject, however, in the case of Incentive Stock Options (as hereinafter defined), to any limitation required under the Code. Shares issued under the Plan may consist in whole or in part of authorized
but unissued shares or treasury shares." 

			
	 	 	Adopted by the Board of Directors on February 21, 2002
	

 	
 	

Adopted by the Stockholders on May 22, 2002

10

 
 AMENDMENT NO 2. TO

2000 STOCK INCENTIVE PLAN

OF

SEPRACOR INC.  

        The 2000 Stock Incentive Plan (the "Plan") of Sepracor Inc. be, and hereby is, amended as follows: 

        1.     Section 4,
paragraph (a) is deleted in its entirety and the following is substituted in its place: 

        "(a)    Number of Shares.    Subject to adjustment under Section 8, Awards may be made under the Plan for up to
5,5000,000 shares of common stock, $.10 par value per share, of the Company (the "Common Stock"). If any Award expires or is terminated, surrendered or cancelled without having been fully exercised or
is forfeited in whole or in part or results in any Common Stock not being issued, the unused Common Stock covered by such Award shall again be available for the grant of Awards under the Plan,
subject, however, in the case of Incentive Stock Options (as hereinafter defined), to any limitation required under the Code. Shares issued under the Plan may consist in whole or in part of authorized
but unissued shares or treasury shares." 

			
	 	 	Adopted by the Board of Directors on February 20, 2003
	

 	
 	

Adopted by the Stockholders on May 22, 2003

11

 
 AMENDMENT NO 3. TO

2000 STOCK INCENTIVE PLAN

OF

SEPRACOR INC.  

        The 2000 Stock Incentive Plan (the "Plan"), as amended, of Sepracor Inc. be, and hereby is, further amended as follows: 

        1.     Section 4,
paragraph (a) is deleted in its entirety and the following is substituted in its place: 

        "(a)    Number of Shares.    Subject to adjustment under Section 8, Awards may be made under the Plan for up to
8,000,000 shares of common stock, $.10 par value per share, of the Company (the "Common Stock"). If any Award expires or is terminated, surrendered or cancelled without having been fully exercised or
is forfeited in whole or in part or results in any Common Stock not being issued, the unused Common Stock covered by such Award shall again be available for the grant of Awards under the Plan,
subject, however, in the case of Incentive Stock Options (as hereinafter defined), to any limitation required under the Code. Shares issued under the Plan may consist in whole or in part of authorized
but unissued shares or treasury shares." 

			
	 	 	Adopted by the Board of Directors on February 11, 2004.
	

 	
 	

Adopted by the Stockholders on May 19, 2004.

12

 
 AMENDMENT NO. 4 TO

2000 STOCK INCENTIVE PLAN

OF

SEPRACOR INC.  

        The 2000 Stock Incentive Plan (the "Plan"), as amended, of Sepracor Inc. be, and hereby is, further amended as follows: 

        1.     Section 4,
paragraph (a) is deleted in its entirety and the following is substituted in its place: 

        "(a)    Number of Shares.    Subject to adjustment under Section 8, Awards may be made under the Plan for up to
9,500,000 shares of common stock, $.10 par value per share, of the Company (the "Common Stock"). If any Award expires or is terminated, surrendered or cancelled without having been fully exercised or
is forfeited in whole or in part or results in any Common Stock not being issued, the unused Common Stock covered by such Award shall again be available for the grant of Awards under the Plan,
subject, however, in the case of Incentive Stock Options (as hereinafter defined), to any limitation required under the Code. Shares issued under the Plan may consist in whole or in part of authorized
but unissued shares or treasury shares." 

			
	 	 	Adopted by the Board of Directors on April 1, 2005.
	

 	
 	

Adopted by the Stockholders on May 19, 2005.

13

 
 AMENDMENT NO. 5 TO

2000 STOCK INCENTIVE PLAN

OF

SEPRACOR INC.  

        The 2000 Stock Incentive Plan (the "Plan") of Sepracor Inc. be and hereby is, amended as follows: 

	1.
	The
following Section 5(h) is hereby added:

	(h)
	Limitation on Repricing.    Unless such action is approved by the Company's stockholders:
(i) no outstanding Option granted under the Plan may be amended to provide an exercise price per share that is lower than the then-current exercise price per share of such
outstanding Option (other than adjustments pursuant to Section 8), and (ii) the Board may not cancel any outstanding option (whether or not granted under the Plan) and grant in
substitution therefor new Awards under the Plan covering the same or a different number of shares of Common Stock and having an exercise price per share lower than the then-current
exercise price per share of the cancelled Option.

	2.
	Section 9(f)
is hereby deleted in its entirety and replaced with the following:

	(f)
	Amendment of Plan.    Except as prohibited by Section 5(h), the Board may amend, modify or
terminate any outstanding Award, including but not limited to, substituting therefore another Award of the same or a different type, changing the date of exercise or realization, and converting an
Incentive Stock Option to a Non-Statutory Stock Option, provided that the Participant's consent to such action shall be required unless the Board determines that the action, taking into
account any related action, would not materially and adversely affect the Participant. 

Adopted
by the Board of Directors on May 13, 2005 

14

 
 AMENDMENT NO. 6 TO

2000 STOCK INCENTIVE PLAN

OF

SEPRACOR INC.  

        The 2000 Stock Incentive Plan (the "Plan") of Sepracor Inc. be and hereby is, amended as follows: 

        1.     Section 4,
paragraph (a) is deleted in its entirety and the following is substituted in its place: 

        "(a)    Number of Shares.    Subject to adjustment under Section 8, Awards may be made under the Plan for up to
11,500,000 shares of common stock, $.10 par value per share, of the Company (the "Common Stock"). If any Award expires or is terminated, surrendered or cancelled without having been fully exercised or
is forfeited in whole or in part or results in any Common Stock not being issued, the unused Common Stock covered by such Award shall again be available for the grant of Awards under the Plan,
subject, however, in the case of Incentive Stock Options (as hereinafter defined), to any limitation required under the Code. Shares issued under the Plan may consist in whole or in part of authorized
but unissued shares or treasury shares." 

			
	 	 	Adopted by the Board of Directors on April 5, 2006.
	

 	
 	

Adopted by the Stockholders on May 18, 2006.

15

 
 AMENDMENT NO. 7 TO

2000 STOCK INCENTIVE PLAN

OF

SEPRACOR INC.  

        The 2000 Stock Incentive Plan (the "Plan"), as amended, of Sepracor Inc. be, and hereby is, further amended as follows: 

        1.     Section 4,
paragraph (a) is deleted in its entirety and the following is substituted in its place: 

        "(a)    Number of Shares.    Subject to adjustment under Section 8, Awards may be made under the Plan for up to
13,500,000 shares of common stock, $.10 par value per share, of the Company (the "Common Stock"). If any Award expires or is terminated, surrendered or cancelled without having been fully exercised or
is forfeited in whole or in part or results in any Common Stock not being issued, the unused Common Stock covered by such Award shall again be available for the grant of Awards under the Plan,
subject, however, in the case of Incentive Stock Options (as hereinafter defined), to any limitation required under the Code. Shares issued under the Plan may consist in whole or in part of authorized
but unissued shares or treasury shares." 

			
	 	 	Adopted by the Board of Directors on March 8, 2007.
	

 	
 	

Adopted by the Stockholders on May 15, 2007.

16

 

   AMENDMENT NO. 8 TO

2000 STOCK INCENTIVE PLAN

OF

SEPRACOR INC  

        The 2000 Stock Incentive Plan (the "Plan") of Sepracor Inc. be, and hereby is, amended as follows: 

        1.     Section 4,
paragraph (a) is hereby deleted in its entirety and the following is substituted in its place: 

        "(a)    Number of Shares; Share Counting.    

        (1)    Authorized Number of Shares.    Subject to adjustment under Section 8, Awards may be made under the Plan
for up to 15,000,000 shares of common stock, $.10 par value per share, of the Company (the "Common Stock"). 

        (2)    Share Counting.    For purposes of counting the number of shares available for the grant of Awards under the
Plan and under the sublimits contained in Sections 4(b), (i) all shares of Common Stock covered by stock appreciation rights ("SARs") shall be counted against the number of shares
available for the grant of Awards; provided, however, that SARs that may be settled in cash only shall not be so counted; (ii) if any Award (A) expires or is terminated, surrendered or
canceled without having been fully exercised or is forfeited in whole or in part (including as the result of shares of Common Stock subject to such Award being repurchased by the Company at the
original issuance price pursuant to a contractual repurchase right) or (B) results in any Common Stock not being issued (including as a result of an SAR that was settleable either in cash or in
stock actually being settled in cash), the unused
Common Stock covered by such Award shall again be available for the grant of Awards; provided, however, in the case of Incentive Stock Options (as hereinafter defined), the foregoing shall be subject
to any limitations under the Code; and provided further, in the case of SARs, that the full number of shares subject to any stock-settled SAR shall be counted against the shares available under the
Plan and against the sublimits listed in the first clause of this Section regardless of the number of shares actually used to settle such SAR upon exercise; (iii) shares of Common Stock
delivered (either by actual delivery or attestation) to the Company by a Participant to (A) purchase shares of Common Stock upon the exercise of an Award or (B) satisfy tax withholding
obligations (including shares retained from the Award creating the tax obligation) shall not be added back to the number of shares available for the future grant of Awards; and (iv) shares of
Common Stock repurchased by the Company on the open market using the proceeds from the exercise of an Award shall not increase the number of shares available for future grant of Awards." 

        2.    Section 7
is hereby deleted in its entirety and the following is substituted in its place: 

        "The
Board shall have the right to grant other Awards based upon the Common Stock having such terms and conditions as the Board may determine, including the grant of shares based upon
certain conditions, the grant of securities convertible into Common Stock and the grant of stock appreciation rights. Notwithstanding the foregoing, with respect to any SAR granted by the Board under
the Plan: 

        (a)   The
exercise price applicable to any such SAR shall not be less than 100% of the Fair Market Value on the date the SAR is granted; provided that if the Board approves
the grant of a SAR with an exercise price to be determined on a future date, the exercise price shall be not less than 100% of the Fair Market Value on such future date; and 

        (b)   unless
such action is approved by the Company's stockholders: (1) no outstanding SAR granted under the Plan may be amended to provide an exercise price per share
that is 

17

 

lower
than the then-current exercise price per share of such outstanding SAR (other than adjustments pursuant to Section 8) and (2) the Board may not cancel any outstanding
SAR (whether or not granted under the Plan) and grant in substitution therefor new Awards under the Plan covering the same or a different number of shares of Common Stock and having an exercise price
per share lower than the then-current exercise price per share of the cancelled SAR." 

			
	 	 	Adopted by the Board of Directors on April 4, 2008.
	

 	
 	

Adopted by the Stockholders on May 20, 2008.

18

QuickLinks

Exhibit 10.9

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00146-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00146-of-00352.parquet"}]]