Document:

EXHIBIT 10.10
swissfirst
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swissfirst Bank AG

                               OTC Contract Note

Buyer:                           swissfirst Bank AG
                                 Herrn T. Maag
                                 Fax 01 204 81 81

Seller:                          Roche Holdings, Inc.
                                 Mr. Marcel F. Kohler
                                 Wilmington, DE 19801

Number of Contracts:             47,000

Call/Put:                        Call

Option Style:                    European

Underlying:                      Laboratory Corp of America Holdings

Security Number:                 US50540R4092

Multiplier                       1

Trade Date:                      17, January, 2002

Value Date:                      23, January, 2002

Expiration Date:                 20, September, 2002

Strike Price:                    USD 75.

Price Per Option:                USD 10.00

Total Premium:                   USD 470,000

Total Underlying Value:          USD 3,525,000

Payment Instructions:            swissfirst Bank AG. for account Nr. 3671_0
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To be transmitted by telefax to swissfirst Bank AG:
                                             Telefax Number +4441-1-204 81 81
Acknowledged by:Roche Holdings, Inc.EXHIBIT 10.11
swissfirst
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swissfirst Bank AG

                                                              OTC Contract Note

Buyer:                           swissfirst Bank AG
                                 Herrn T. Maag
                                 Fax 01 204 81 81

Seller:                          Roche Holdings, Inc.
                                 Mr. Marcel F. Kohler
                                 Wilmington, DE 19801

Number of Contracts:             161,250

Call/Put:                        Call

Option Style:                    European

Underlying:                      Laboratory Corp of America Holdings

Security Number:                 US50540R4092

Multiplier                       1

Trade Date:                      11, February, 2002

Value Date:                      14, February, 2002

Expiration Date:                 20, September, 2002

Strike Price:                    USD 75.

Price Per Option:                USD 14.48

Total Premium:                   USD 2,334,900

Total Underlying Value:          USD 12,093,750

Payment Instructions:            swissfirst Bank AG. for account Nr. 3671_0
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To be transmitted by telefax to swissfirst Bank AG:
                                             Telefax Number +4441-1-204 81 81
Acknowledged by:  Roche Holdings, Inc.EXHIBIT 10.12
swissfirst
--------------------------------------------------------------------------------

swissfirst Bank AG

                               OTC Contract Note

Buyer:                           swissfirst Bank AG
                                 Herrn T. Maag
                                 Fax 01 204 81 81

Seller:                          Roche Holdings, Inc.
                                 Mr. Marcel F. Kohler
                                 Wilmington, DE 19801

Number of Contracts:             93,824

Call/Put:                        Call

Option Style:                    European

Underlying:                      Laboratory Corp of America Holdings

Security Number:                 US50540R4092

Multiplier                       1

Trade Date:                      12, February, 2002

Value Date:                      15, February, 2002

Expiration Date:                 20, September, 2002

Strike Price:                    USD 75.

Price Per Option:                USD 13.27

Total Premium:                   USD 1,245,044,48

Total Underlying Value:          USD 7,036,800

Payment Instructions:            your account 3671_0 at swissfirst Bank AG
                                 will be credited
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To be transmitted by telefax to swissfirst Bank AG:
                                             Telefax Number +4441-1-204 81 81
Acknowledged by: Roche Holdings, Inc.EXHIBIT 10.13
swissfirst
--------------------------------------------------------------------------------

swissfirst Bank AG
Bellariastrasse 23
CH-8002 Zurich       OTC Contract Note                     REF:          SWFB036
                     ------------------------              ----
                     The following transaction was broked and executed
                     through swissfirst Bank AG:

Buyer:                           swissfirst Bank AG, Zurich
                                 Contact Person: Mr. M. Massarotti

Seller:                          Roche Holdings, Inc., Wilmington, USA
                                 Contact Person: Mr. Marcel F. Kohler

Number of Contracts:             500,000

Call/Put:                        Call

Option Style:                    European

Underlying:                      Laboratory Corp of America Holdings

Security Number:                 US50540R4092

Multiplier                       1

Trade Date:                      November 20, 2001

Value Date:                      November 26, 2001

Expiration Date:                 November 15, 2002

Strike Price:                    USD 80.00

Price Per Option:                USD 12.93

Total Premium:                   USD 6,465,000.00

Total Underlying Value:          USD 40,000,000.00

                                                                        S.E.&O.
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To be transmitted by telefax to swissfirst Bank AG: Telefax
Number +4441-1-204 81 Acknowledged by: Roche Holdings, Inc., Wilmington,
USAEXHIBIT 10.14
swissfirst
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swissfirst Bank AG
Bellariastrasse 23
CH-8002 Zurich         OTC Contract Note                  REF:          SWFB039
                       ------------------------           ----
                       The following transaction was broked and executed
                       through swissfirst Bank AG:

Buyer:                           swissfirst Bank AG, Zurich
                                 Contact Person: Mr. M. Massarotti

Seller:                          Roche Holdings, Inc., Wilmington, USA
                                 Contact Person: Mr. Marcel F. Kohler

Number of Contracts:             50,000

Call/Put:                        Call

Option Style:                    European

Underlying:                      Laboratory Corp of America Holdings

Security Number:                 US50540R4092

Multiplier                       1

Trade Date:                      November 21, 2001

Value Date:                      November 27, 2001

Expiration Date:                 November 15, 2002

Strike Price:                    USD 80.00

Price Per Option:                USD 13.44

Total Premium:                   USD 672,000.00

Total Underlying Value:          USD 400,000.00

                                                                        S.E.&O.
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To be transmitted by telefax to swissfirst Bank AG:
Telefax Number +4441-1-204 81 81 Acknowledged by:
Roche Holdings, Inc., Wilmington, USAEXHIBIT 10.15
swissfirst
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swissfirst Bank AG

                              OTC Contract Note
                              -----------------

Seller:                          Roche Holdings, Inc.
                                 Herrn M.F. Kohler

Buyer:                           swissfirst Bank AG
                                 Herrn T. Maag
                                 Fax 01 204 81 81

Number of Contracts:             200,000

Call/Put:                        Call

Option Style:                    European

Underlying:                      Laboratory Corp of America Holdings

Security Number:                 US50540R4092

Multiplier                       1

Trade Date:                      November 23, 2001

Value Date:                      November 28, 2001

Expiration Date:                 November 15, 2002

Strike Price:                    USD 80.00

Price Per Option:                USD 13.1

Total Premium:                   USD 2,620,000

Total Underlying Value:          USD 16,000,000

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To be transmitted by telefax to swissfirst Bank AG:
Telefax Number +4441-1-204 81 81
Acknowledged by: Roche Holdings, Inc.EXHIBIT 10.16

swissfirst
--------------------------------------------------------------------------------
swissfirst Bank AG
Bellariastrasse 23
CH-8002 Zurich                OTC Contract Note
                              ------------------------
                              The following transaction was broked and executed
                              through swissfirst Bank AG:

Seller:                          Roche Holdings, Inc., Wilmington, USA
                                 Contact Person: Mr. Marcel F. Kohler

Buyer:                           swissfirst Bank AG, Zurich
                                 Contact Person: Mr. M. Massarotti

Number of Contracts:             65,000

Call/Put:                        Call

Option Style:                    European

Underlying:                      Laboratory Corp of America Holdings

Security Number:                 US50540R4092

Multiplier                       1

Trade Date:                      November 26, 2001

Value Date:                      November 29, 2001

Expiration Date:                 November 15, 2002

Strike Price:                    USD 80.00

Price Per Option:                USD 13.00

Total Premium:                   USD 845,000.00

Total Underlying Value:          USD 5,200,000.00

                                                                        S.E.&O.
--------------------------------------------------------------------------------

To be transmitted by telefax to swissfirst Bank AG:
Telefax Number +4441-1-204 81 81
Acknowledged by:  Roche Holdings, Inc., Wilmington, USA

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