Document:

<PAGE>

Exhibit 4.2

THE WARRANTS AND COMMON STOCK ISSUABLE UPON THEIR EXERCISE HAVE NOT BEEN
REGISTERED UNDER THE SECURITIES ACT OF 1933 (THE "ACT") OR APPLICABLE STATE
SECURITIES LAWS. THESE SECURITIES MAY NOT BE OFFERED FOR SALE, SOLD, DELIVERED
AFTER SALE, TRANSFERRED, PLEDGED OR HYPOTHECATED IN THE ABSENCE OF AN EFFECTIVE
REGISTRATION STATEMENT COVERING SUCH SECURITIES UNDER THE ACT AND ANY SUCH STATE
LAWS OR THE AVAILABILITY OF AN EXEMPTION FROM REGISTRATION THEREUNDER.

                       PHARMAKINETICS LABORATORIES, INC.

                         COMMON STOCK PURCHASE WARRANT

     1.   Issuance. For good and valuable consideration the receipt of which is
          --------
hereby acknowledged, PHARMAKINETICS LABORATORIES, INC., a Maryland corporation
(the "Company"), hereby grants to ALTANA, INC. (the "Holder") the right to
purchase at any time and from time to time until 5:00 P.M. Eastern Standard Time
on _______ ___, 2003 (the "Expiration Date"), 100,000 fully paid and
nonassessable shares of the Company's Common Stock, par value $0.005 per share
(the "Common Stock") at an exercise price of $6.00 per share (the "Exercise
Price"), subject to adjustment as set forth in Section 6.

     2.   Exercise. Subject to Section 7 hereof, the warrants represented by
          --------
this Certificate (the "Warrants") are exercisable until the Expiration Date, in
whole or in part, by surrendering to the Company (i) this Certificate, (ii) the
attached form of notice of exercise of the Warrants, and (iii) unless the Holder
elects "cashless exercise" of the Warrants, cash or a certified or official bank
check in the amount of the aggregate Exercise Price. In the event the Holder
elects cashless exercise of the Warrants, the Holder shall be entitled to
receive a number of shares of Common Stock equal in Market Value to the
difference between the Market Value of the shares of Common Stock issuable upon
exercise of the Warrants and the aggregate cash Exercise Price thereof. For
purposes of this Section 2, "Market Value" shall be an amount equal to the
average of the closing sales price of a share of Common Stock for the ten (10)
days immediately preceding the Company's receipt of the form of notice of
exercise duly executed, via delivery or facsimile, multiplied by the number of
shares of Common Stock to be issued upon exercise. Upon surrender of this
Certificate and the notice of exercise form duly executed, together with payment
of the Exercise Price for the shares of Common Stock purchased, the Company
promptly shall send or cause to be sent to the Holder a certificate or
certificates representing the shares of Common Stock purchased. Upon the
exercise of less than all of the Warrants evidenced by this Certificate, the
Company promptly shall send to the Holder a new Warrant Certificate representing
the unexercised portion of the Warrants.

     3.   Reservation of Shares. The Company agrees that at all times during the
          ---------------------
period of exercise of these Warrants there shall be reserved for issuance at
least that number of shares of Common Stock required to be issued upon exercise
of the Warrants (the "Warrant Shares").
<PAGE>

     4.   Mutilation or Loss of Warrant. Upon receipt by the Company of evidence
          -----------------------------
satisfactory to it of the loss, theft, destruction or mutilation of this Warrant
Certificate, and, in the case of loss, theft or destruction, receipt of
reasonably satisfactory indemnification, and, in the case of mutilation, upon
surrender and cancellation of this Certificate, the Company will execute and
deliver a new Warrant Certificate of like tenor and date and any such lost,
stolen, destroyed or mutilated Warrant Certificate shall thereupon become void.

     5.   Rights of the Holder.  The Holder shall not, by virtue hereof, be
          --------------------
entitled to any rights of a stockholder in the Company, either at law or equity,
and the rights of the Holder are limited to those expressed in this Warrant
Certificate and are not enforceable against the Company except to the extent set
forth herein, and the Holder, by its acceptance of this Warrant Certificate,
consents to and agrees to be bound by and to comply with the terms of this
Warrant including, without limitation the provisions of Section 7 hereof.

     6.   Protection Against Dilution. The number of shares of Common Stock that
          ---------------------------
the Holder is entitled to purchase upon exercise of the Warrants and the
Exercise Price shall be subject to adjustment from time to time as follows:

          (a)  Adjustment for Subdivision.  If the Company at any time
               --------------------------
subdivides (by any stock split, stock dividend, recapitalization or otherwise)
the outstanding shares of Common Stock into a greater number of shares, the
number of shares that the Holder is entitled to purchase upon exercise of the
Warrants shall be proportionately increased and the Exercise Price in effect
immediately prior to such subdivision shall be proportionately reduced, and if
the Company at any time combines (by reverse stock split or otherwise) the
outstanding shares of Common Stock into a smaller number of shares, the number
of shares that the Holder is entitled to purchase upon exercise of the Warrants
shall be proportionately decreased and the Exercise Price in effect immediately
prior to such combination and the number of shares of Common Stock to be
received by the Holder pursuant to the Warrants shall be proportionately
increased.

          (b)  Adjustment for Reorganization. Any capital reorganization,
               -----------------------------
reclassification, consolidation, merger or sale of all or substantially all of
the Company's assets with or into another person or entity that is effected in
such a manner that holders of Common Stock are entitled to receive (either
directly or upon subsequent liquidation) stock, securities or assets with
respect to or in exchange for Common Stock shall be referred to herein as an
"Organic Change." Prior to the consummation of any Organic Change, the Company
shall make appropriate lawful provisions to ensure that the Holder shall
thereafter have the right to acquire and receive upon exercise of the Warrants
during the period specified herein and upon payment of the Exercise Price then
in effect such shares of stock, securities or assets as the Holder would have
received in connection with such Organic Change if the Holder had exercised the
Warrants immediately prior to such Organic Change.

     7.   Transfer or Exercise Complies with Securities Act. The Holder of this
          -------------------------------------------------
Warrant, by its acceptance hereof, hereby represents and warrants that such
Holder understands and agrees that (a) the Warrant and the Warrant Shares
issuable upon the exercise of this Warrant have not been registered under
<PAGE>

either the Securities Act of 1933, as amended (the "Act"), or applicable state
securities laws (the "State Acts"), and the Company has no obligation to
register the Warrant or such Warrant Shares; (b) the Warrant may be exercised
only if the Warrant Shares have been registered under the Act and the applicable
State Acts or upon the issuance to the Company of an opinion of counsel
satisfactory to counsel to the Company and/or submission to the Company of such
evidence as may be satisfactory to counsel to the Company, in each such case, to
the effect that any such exercise shall not be in violation of the Act and the
applicable State Acts; (c) this Warrant may not be sold, pledged, hypothecated,
donated, assigned or otherwise transferred (whether or not for consideration),
in whole or in part, by the Holder, unless the Warrant has been registered under
the Act and the applicable State Act or upon the issuance to the Company of an
opinion of counsel satisfactory to counsel to the Company and/or submission to
the Company of such evidence as may be satisfactory to counsel to the Company,
in each such case, to the effect that any such transfer shall not be in
violation of the Act and the applicable State Acts and (d) the Warrant Shares
issuable upon the exercise of this Warrant may not be sold, pledged,
hypothecated, donated, assigned or otherwise transferred (whether or not for
consideration), in whole or in part, by the Holder, unless the Warrant Shares
have been registered under the Act and the applicable State Acts or upon the
issuance to the Company of an opinion of counsel satisfactory to counsel to the
Company and/or upon submission to the Company of such evidence as may be
satisfactory to counsel to the Company, in each such case, to the effect that
any such transfer shall not be in violation of the Act and the State Acts. The
Holder hereby agrees that the Company's obligation to deliver Warrant Shares
upon exercise of this Warrant is subject to the requirement that the Holder
deliver to the Company, if requested by the Company, such certificates,
documents or other information as the Company or its counsel may reasonably
request for the purpose of establishing compliance with the Act and applicable
State Acts. Each Warrant Certificate and the Warrant Shares shall contain a
legend on the face thereof, in form and substance satisfactory to counsel for
the Company, setting forth the restrictions on transfer contained in this
Section 7.

     8.   Notices.  Any notice or other communication required or permitted
          -------
hereunder shall be in writing and shall be delivered personally, telegraphed,
telexed, sent by facsimile transmission or sent by certified, registered or
express mail, postage pre-paid. Any such notice shall be deemed given when so
delivered personally, telegraphed, telexed or sent by facsimile transmission,
or, if mailed, two days after the date of deposit in the United States mails, as
follows:
<PAGE>

          If to the Company:

                         PharmaKinetics Laboratories, Inc.
                         302 West Fayette Street
                         Baltimore, MD 21201
                         Attention: President
                         Telephone: (410) 385-4500
                         Facsimile: (410) 385-1957

          with a copy to:

                         Ober, Kaler, Grimes & Shriver
                         120 E. Baltimore Street
                         Baltimore, MD 21202
                         Attention: Melissa A. Warren, Esquire
                         Telephone: (410) 347-7684
                         Facsimile: (410) 547-0699

          If to Holder:

                         Altana Inc.
                         60 Baylis Road
                         Melville, New York  11747
                         Attention: Art Dulik, Chief Financial Officer
                         Telephone: (516) 45-7677
                         Facsimile: (516) 454-6389

          with a copy to:

                         Simmons, Jannace & Stagg, L.L.P.
                         The Financial Center
                         90 Merrick Avenue - Suite 102
                         East Meadow, New York  11554
                         Attention: Kevin P. Simmons, Esquire
                         Telephone: (516) 357-8100
                         Facsimile: (516) 357-8111

Any party may designate another address or person for receipt of notices
hereunder by notice given to the other parties in accordance with this Section
8.

     9.   Transfer. The Holder shall not transfer the Warrants without the prior
          --------
written consent of the Company.

     10   Governing Law. This Warrant Certificate shall be governed by and
          -------------
construed in accordance with
<PAGE>

the laws of the state of Maryland.

     11.  Supplements and Amendments. This Warrant Certificate may be amended or
          --------------------------
supplemented only by an instrument in writing signed by the parties hereto.

     12.  Counterparts. This Warrant Certificate may be executed in any number
          ------------
of counterparts and each such counterpart shall for all purposes be deemed to be
an original, and all such counterparts shall together constitute one and the
same instrument.

     IN WITNESS WHEREOF, PharmaKinetics Laboratories, Inc. has caused this
Warrant to be executed on its behalf as of the ____ day of _______, 2000.

ATTEST:                                 PHARMAKINETICS LABORATORIES, INC.

________________________________        By:___________________________(SEAL)
Secretary                                          President
<PAGE>

                        NOTICE OF EXERCISE OF WARRANTS

     The undersigned hereby irrevocably elects to exercise the right,
represented by the attached Common Stock Purchase Warrant Certificate dated as
of _______ ___, 2000 (the "Certificate") to purchase _______ shares of the
Common Stock, par value $0.005 per share, of PharmaKinetics Laboratories, Inc.
and either (i) tenders herewith payment in accordance with said Certificate or
(ii) elects "cashless exercise" in accordance with the Certificate, as indicated
below.

     The undersigned hereby confirms and acknowledges that the undersigned will
not offer, sell or otherwise dispose of any shares of Common Stock received upon
exercise of the Warrants except pursuant to an effective registration statement
under the Securities Act of 1933, as amended, and applicable state securities
laws or pursuant to an exemption form registration in accordance with such Act
and laws.

     Please issue in the name of the undersigned a new Common Stock Purchase
Warrant Certificate representing the unexercised portion of the Warrants
represent by the attached Certificate.

     Please issue the stock certificate(s) in the names and denominations and
deliver them to the addresses set forth below:

_________________________________________
_________________________________________
_________________________________________
_________________________________________

Dated:______________________

By:_________________________

[_]       CASH:  $ _______________________

[_]  CASHLESS EXERCISE<PAGE>

Exhibit 4.3

                          FRONT OF STOCK CERTIFICATE

             Incorporated Under the Laws of the State of Maryland

Number                                                             Shares

--                                                                 --

                       PharmaKinetics Laboratories, Inc.
       250,000 Shares of Class B Convertible Preferred Stock Authorized

This certifies that ________________ is the registered holder of
__________________ shares of Class B Convertible Preferred Stock transferable
only on the books of the Corporation by the holder hereof in person or by
Attorney upon surrender of this Certificate properly endorsed.

In witness whereof, the said Corporation has caused this Certificate to be
signed by its duly authorized officers and its corporate seal to be hereunto
affixed this ____ day of ________________ A.D. ____________.

__________________________________         ________________________________
James M. Wilkinson, II, President          Taryn L. Kunkel, Secretary

                        Shares without par value each.
<PAGE>

                           BACK OF STOCK CERTIFICATE

The securities represented by this certificate have been purchased pursuant to
an investment representation on the part of the holder hereof and shall not be
sold, pledged, hypothecated or otherwise transferred, by the holder except upon
the issuance to the Corporation of an opinion of counsel and/or the submission
to the Corporation of such other evidence as may be satisfactory to counsel for
the Corporation, to the effect that any such transfer shall not be in violation
of the Securities Act of 1933, as amended, and applicable state securities laws.

The Corporation will furnish to any stockholder on request and without charge a
full statement of the designations and any preferences, conversion or other
rights, voting powers, restrictions, limitation as to dividends, qualifications,
and terms and conditions of redemption of the stock of each class which the
corporation is authorized to issue; the differences in the relative rights and
preferences between the shares of any series of preferred or special class of
stock and the authority of the board of directors to set the relative rights and
preferences of subsequent series; and restrictions on transferability.

For value received, _________ hereby sell, assign, and transfer unto
_________________________ ________________ shares represented by the within
Certificate, and do hereby irrevocably constitute and appoint _____________
attorney to transfer the said shares on the books of the within named
corporation with full power of substitution in the premises.

Dated__________________       Year ______________________

In the presence of _______________________        ____________________

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00008-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00008-of-00352.parquet"}]]