Document:

Exhibit 4.3

 

SECOND AMENDED AND RESTATED REGISTRATION
RIGHTS AGREEMENT

 

THIS SECOND AMENDED
AND RESTATED REGSITRATION RIGHTS AGREEMENT (this “Agreement”) is entered into as of the 22nd day of July, 2014,
but effective as of the consummation of the IPO (as defined below), by and among Macrocure Ltd., an Israeli company (the
“Company”), and the holders of the Company’s securities who are listed on Schedule A hereto
(the “Investors”).

 

W I T N E S S E
T H:

 

WHEREAS,
the Company and certain of the Investors were parties to that certain Registration Rights Agreement, dated as of March 30, 2011
(the “Original Registration Rights Agreement”), which was amended and restated pursuant to that certain First
Amended and Restated Registration Rights Agreement, dated as of May 3, 2012 (the “Previous Registration Rights Agreement”);

 

WHEREAS,
Section 15.6 of the Previous Registration Rights Agreement provides that the Previous Registration Rights Agreement may be amended
with the written consent of the Company and the Preferred Majority Holders (as such term is defined in the Previous Registration
Rights Agreement), and the Investors party hereto include the Preferred Majority Holders;

 

WHEREAS,
the Company currently anticipates effecting an initial public offering of its Ordinary Shares (as defined in Section 1 below)
in the United States (the “IPO”), and the listing of the Ordinary Shares on the NASDAQ Stock Market (the “Listing”);
and

 

WHEREAS,
in connection with the IPO and the Listing, the Company and the Investors wish to terminate the Previous Registration Rights Agreement
and replace it in its entirety with the agreements and covenants set forth herein.

 

NOW,
THEREFORE, THE PARTIES HERETO HEREBY AGREE AS FOLLOWS:

 

		1.	Definitions. For purposes of this Agreement:

 

		1.1	The term “Act” means the United States
Securities Act of 1933, as amended.

 

		1.2	The term “Affiliate” means with respect
to any Person, any Person directly or indirectly Controlling, Controlled by, or under common Control with, such Person at any
time during the period for which the determination of affiliation is being made. With respect to Viola and Vaizra, an Affiliate
shall also mean any of such party's co-investors, limited partners, general partners or the limited or general partners of such
limited or general partners, or entities that manage or co-manage, or are managed or whose account is managed by, directly or
indirectly, by Viola and Vaizra, as applicable, or such Affiliate or any of their respective limited partners, business partners,
general partners or the limited or general partners of such limited or general partners or management Person. With respect to
each of Vaizra, Kuf Dalet, Lender and/or JGPY, an Affiliate shall also mean each of Vaizra, Kuf Dalet, Lender and/or JGPY.

 

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		1.3	The term “Business Day” means any day
that is not Friday, Saturday or Sunday or any other day on which banks in the City of New York or the State of Israel are permitted
or required to be closed.

 

		1.4	The term “Control” means the holding
of at least 50.1% of the voting power of a corporation or other entity, or the right to appoint more than half of the directors,
managers or members of the other management body of an entity.

 

		1.5	The term “Form F-3” means
such form under the Act as in effect on the date hereof or any registration form under the Act subsequently adopted by the SEC
that permits inclusion or incorporation of substantial information by reference to other documents filed by the Company with the
SEC.

 

		1.6	The term “Holder” means any person
owning Registrable Securities or any assignee thereof in accordance with Section ‎10 hereof.

		 	 

		1.7	The term “Initial Offering” means the
Company’s first firm commitment underwritten public offering of its Ordinary Shares registered under the Act or the equivalent
law of another jurisdiction. For purposes of clarity, the IPO (as defined in the above Recitals to this Agreement), upon consummation,
shall constitute the Initial Offering.

		 	 

		1.8	The term “JGPY” means Jerusalem Global
Pele Yo’etz Ltd.

		 	 

		1.9	The term “Kuf Dalet” means Kuf Dalet
(104) Ltd.

		 	 

		1.10	The term “Lender” means Yitzhak (Viatcheslav)
Mirilashvili.

		 	 

		1.11	The term “1934 Act” means the United
States Securities Exchange Act of 1934, as amended.

		 	 

		1.12	The term “register,” “registered,”
and “registration” refer to a registration effected by preparing and filing a registration statement or similar
document in compliance with the Act, and the declaration or ordering of effectiveness of such registration statement or document.

		 	 

		1.13	The term “Ordinary Shares” means the
Company’s ordinary shares having a nominal value of NIS 0.01 per share.

		 	 

		1.14	The term “Original Agreement Date”
means March 30, 2011.

		 	 

		1.15	The term “Permitted Transferees” means
(a) a transferee by operation of law; (b) in the case of a Holder who is a natural person, (i) an entity that is wholly owned
by such Holder and (ii) the spouse or children (including adopted children) of such Holder; (c) a trust that does not permit any
of the settled property or the income therefrom to be applied otherwise than for the benefit of the Holder and no power or control
over the voting powers conferred by any shares are subject to the consent of any person other than the trustees of such Holder;
(d) a Person who is an Affiliate of the transferor; (e) without derogating from the aforesaid, if such Holder is a limited or
general partnership or a limited liability company or a corporation, its partners, members, Affiliates, or affiliated partnerships
managed by the same management company or managing (general) partner or by an entity that is Affiliated with such management company
or managing (general) partner and any fund (or shareholder or partner of any such fund), or any beneficiary of a trust or an account
or arrangement, managed by such Holder or by the general partner or managing entity of such Holder or by an Affiliate thereof;
(f) the Company, with respect to (i) repurchase of Registrable Securities at par value or for no consideration from a Holder,
or (ii) repurchase pursuant to an agreement that was approved by the Board of Directors of the Company or upon termination of
service or employment at cost, or (g) any Person for whom a Holder holds Registrable Securities in trust; provided however,
that in any of the foregoing events (other than clause (f)), the Permitted Transferee shall have first assumed in writing, a copy
of which shall have been delivered to the Company, all of the transferring Holder's obligations under this Agreement.

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		1.16	The term “Person” means an individual,
corporation, partnership, joint venture, limited liability company, trust, any other corporate entity and any unincorporated association
or organization.

		 	 

		1.17	The term “Preferred A Shares” means
the Company’s Series A Preferred Shares having a nominal value of NIS 0.01 per share.

		 	 

		1.18	The term “Preferred Majority Holders”
has the meaning set forth in the Articles of Association of the Company, as they may be amended or replaced from time to
time (the “Articles”).

		 	 

		1.19	The term “Registrable Securities” means
(i) the Ordinary Shares issuable or issued upon conversion of Preferred A Shares of the Company, (ii) all Ordinary Shares
that any Investor (or its Permitted Transferee) may have purchased since the Original Agreement Date or may hereafter purchase
pursuant to its preemptive rights, rights of first offer, anti-dilution protection, or otherwise in respect of (x) Preferred A
Shares or (y) Ordinary Shares issued or issuable upon conversion of Preferred A Shares, (iii) any Ordinary Shares issuable upon
exercise of warrants to purchase Preferred A Shares that become exercisable for Ordinary Shares instead due to the effectiveness
of an automatic conversion of all outstanding Preferred A Shares into Ordinary Shares under the Articles (as in effect as of the
time of such conversion), (iv) any Ordinary Shares of the Company issued as (or issuable upon the conversion or exercise of any
warrant, right or other security that is issued as) a dividend or other distribution with respect to, or in exchange for, or in
replacement of, the shares referenced in (i), (ii) and (iii) above, (v) the Ordinary Shares issuable upon exercise of the Warrant
to purchase 9,560 Ordinary Shares issued by the Company to the Lender on July 10, 2014 and (vi) any Ordinary Shares purchased
by a Holder from the underwriters through a “directed share program” or other purchase from the underwriters in the
Initial Offering (but not Ordinary Shares purchased by a holder in the market following consummation of the Initial Offering).
The number of “Registrable Securities” outstanding shall be determined by adding the number of currently outstanding
Ordinary Shares that constitute Registrable Securities to the number of Ordinary Shares that, when issued pursuant to the exercise
or conversion of then exercisable or convertible securities, would constitute Registrable Securities. Notwithstanding the foregoing,
Ordinary Shares shall cease to be “Registrable Securities” upon the earliest to occur of the following: (x) five (5)
years following the consummation of the Initial Offering, (y) as to any Holder, such time at which such Holder (together with
any Affiliates of the Holder with whom such Holder must aggregate its sales under Rule 144 promulgated under the Act) is
able to sell all Registrable Securities within any three (3) month period and (z) upon sale by a Holder in a transaction in which
such Holder’s rights under this Agreement are not assigned in accordance with the provisions of Section 11.

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		1.20	The term “SEC” means the United States
Securities and Exchange Commission.

		 	 

		1.21	The term “Vaizra” means Vaizra Ventures
Ltd., Kuf Dalet, the Lender and/or JGPY and/or any of their Permitted Transferees.

		 	 

		1.22	The term “Viola” means Viola Private
Equity I, L.P. and any of its Permitted Transferees.

 

		2.	Demand Registration.

 

		2.1	Subject to the conditions of this Section ‎2,
if at any time that is after the effective date of the Initial Offering, but subject to the terms of any “lock-up agreement”
entered into by a Holder with an underwriter of the Initial Offering (unless waived by such underwriter), the Company shall receive
a written request (a “Form F-1 Request Notice”) from the Holders holding at least 50% of the Registrable Securities
then outstanding (the “Initiating Holders”) that the Company file a registration statement under the Act covering
the registration of Registrable Securities pursuant to this Section 2, then the Company shall, within twenty (20) days of the
receipt of such Form F-1 Request Notice, give written notice of such request to all Holders, and subject to the limitations of
this Section ‎2, use best efforts to effect, as soon as practicable, the registration under the Act of all Registrable
Securities that the Holders request to be registered in a written request received by the Company within twenty (20) days of the
mailing of the Company’s notice pursuant to this Section ‎2.1.

		 	 

		2.2	If the Initiating Holders intend to distribute the Registrable
Securities covered by their request by means of an underwritten public offering, they shall so advise the Company as a part of
their request made pursuant to this Section ‎2 and the Company shall include such information in the written notice
referred to in Section ‎2.1. In such event the right of any Holder to include its Registrable Securities in such registration
shall be conditioned upon such Holder’s participation in such underwritten public offering and the inclusion of such Holder’s
Registrable Securities in the underwritten public offering (unless otherwise mutually agreed by a majority in interest of the
Initiating Holders and such Holder) to the extent provided herein. All Holders proposing to distribute their securities through
such underwritten offering shall enter into an underwriting agreement in customary form with the underwriter or underwriters selected
for such underwriting by a majority in interest of the Initiating Holders (which underwriter or underwriters shall be reasonably
acceptable to the Company). Notwithstanding any other provision of this Section ‎2, if the underwriter advises the
Company that marketing factors require a limitation of the number of securities underwritten (including Registrable Securities),
then the Company shall so advise all Holders of Registrable Securities that would otherwise be underwritten pursuant hereto, and
the Company shall include in such registration, (i) first, the Registrable Securities requested to be included therein
by the Holders requesting such registration (the securities so included to be allocated between the Holders on a pro rata basis
based on the number of Registrable Securities held by all such Holders), (ii) second, shares which the Company may wish
to register for its own account, and (iii)  third, other securities requested and entitled to be included in
such registration provided, however, that in any event all Registrable Securities must be included in such registration
prior to any other securities of the Company. If any Holder disapproves of the terms of any such underwriting, such Holder may
elect to withdraw therefrom by written notice to the Company and the underwriter, delivered at least twenty (20) days prior to
the effective date of the registration statement. Any Registrable Securities excluded or withdrawn from such underwritten public
offering shall be withdrawn from the registration.

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		2.3	The Company shall not be required to effect a registration
pursuant to this Section ‎2:

 

		(a)	in any particular jurisdiction in which the Company would
be required to execute a general consent to service of process in effecting such registration, unless the Company is already subject
to service in such jurisdiction and except as may be required under the Act; it being understood that if the Company has registered
its securities in a certain state in the United States in which a registration is required by the Holders pursuant to this Section
‎2– it will not be able to excuse itself from the demand request based on this exclusion; or

		 	 

		(b)	after the Company has effected three (3) registrations
pursuant to this Section ‎2, and such registrations have been declared or ordered effective; or

		 	 

		(c)	if the Initiating Holders, together with the holders of
any other securities of the Company entitled to inclusion in such registration, propose to sell Registrable Securities and such
other securities (if any) at an aggregate price to the public (net of any underwriters’ discounts or commissions) of less
than $5,000,000;

		 	 

		(d)	within a period of one hundred eighty (180) days following
the effective date of a previous registration; or

		 	 

		(e)	such registration could be effected on Form F-3.

 

		2.4	For purposes of Section 2, the Initiating Holders shall
be entitled to determine that a registration shall not be counted as “effected” if, as a result of an exercise of
the underwriter's cutback provisions in Section ‎2.2, fewer than fifty percent (50%) of the total number of Registrable
Securities that Holders have requested to be included in such registration statement are actually included, provided that during
the term of this Agreement, the Initiating Holders shall only be entitled to make a determination under this Section 2.4 two (2)
times.

 

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		3.	Company or “Piggyback” Registration.

 

		3.1	Piggyback into Underwritten Offering. If (but without
any obligation to do so) at any time after the effective date of the Initial Offering, but subject to the terms of any “lock-up
agreement” entered into by a Holder with an underwriter for the Initial Offering (unless waived by such underwriter), the
Company, including if the Company qualifies as a well-known seasoned issuer (within the meaning of Rule 405 under the Act) (a
“WKSI”), proposes to file (i) a prospectus supplement to an effective shelf registration statement (a “Shelf
Registration Statement”), or (ii) a registration statement other than a Shelf Registration Statement for a delayed or
continuous offering pursuant to Rule 415 under the Act, in either case, for the sale of Ordinary Shares for its own account, or
for the benefit of the holders of any of its securities other than the Holders, to an underwriter on a firm commitment basis for
reoffering to the public or in a “bought deal” or “registered direct offering” with one or more investment
banks (collectively, a “Piggy-Back Underwritten Offering”), then as soon as practicable but not less than twenty-five
(25) days prior to the filing of (a) any preliminary prospectus supplement relating to such Piggy-Back Underwritten Offering pursuant
to Rule 424(b) under the Act, (b) any prospectus supplement relating to such Piggy-Back Underwritten Offering pursuant to Rule
424(b) under the Act (if no preliminary prospectus supplement is used) or (c) such registration statement, as the case may be,
the Company shall give notice of such proposed Piggy-Back Underwritten Offering to the Holders and such notice (a “Piggyback
Notice”) shall offer the Holders the opportunity to include in such Piggy-Back Underwritten Offering such number of
Registrable Securities as each such Holder may request in writing. Each such Holder shall then have twenty (20) days after receiving
such notice to request in writing to the Company inclusion of Registrable Securities in the Piggy-Back Underwritten Offering,
except that such Holder shall have two (2) Business Days after such Holder confirms receipt of the notice to request inclusion
of Registrable Securities in the Piggy Back Underwritten Offering in the case of a “bought deal”, “registered
direct offering” or “overnight transaction” where no preliminary prospectus is used. Upon receipt of any such
request for inclusion from a Holder received within the specified time, the Company shall use best efforts to effect the registration
in any registration statement of any of the Holders’ Registrable Securities requested to be included on the terms set forth
in this Agreement. Prior to the commencement of any “road show,” any Holder shall have the right to withdraw its request
for inclusion of its Registrable Securities in any registration by giving written notice to the Company of its request to withdraw
and such withdrawal shall be irrevocable and, after making such withdrawal, such Holder shall no longer have any right to include
Registrable Securities in the Piggy-Back Underwritten Offering as to which such withdrawal was made.

		 	 

		3.2	Piggyback into Shelf Registration. If the Company
does not qualify as a WKSI, (i) the Company shall give each Holder at least twenty-five (25) days’ notice prior to filing
a Shelf Registration Statement and, upon the written request of any Holder, received by the Company within twenty (20) days of
such notice to the Holder, the Company shall include in such Shelf Registration Statement a number of Ordinary Shares equal to
the aggregate number of Registrable Securities requested to be included without naming any requesting Holder as a selling shareholder
and including only a generic description of the holder of such securities (the “Undesignated Registrable Securities”),
(ii) the Company shall not be required to give notice to any Holder in connection with a filing pursuant to Section 3.1 unless
such Holder provided such notice to the Company pursuant to this Section 3.2 and included Undesignated Registrable Securities
in the Shelf Registration Statement related to such filing, and (iii) at the written request of a Holder given to the Company
at least seven (7) days before the date specified in writing by the Company as the Company’s good faith estimate of a launch
of a Piggy-Back Underwritten Offering (or such shorter period to which the Company in its sole discretion consents), the Company
shall use best efforts to effect the registration of any of the Holders’ Undesignated Registrable Securities so requested
to be included and shall file a post-effective amendment or, if available, a prospectus supplement to a Shelf Registration Statement
to include such Undesignated Registrable Securities as any Holder may request, provided that (a) the Company is actively employing
its best efforts to effect such Piggy-Back Underwritten Offering; and (b) the Company shall not be required to effect a post-effective
amendment more than two (2) times in any twelve (12) month period.

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		3.3	Right to Terminate Registration. The Company shall
have the right to terminate or withdraw any registration initiated by it under this Section ‎3 prior to the effectiveness
of such registration or the completion of such offering, whether or not any Holder has elected to include Registrable Securities
in such registration or offering. The expenses of such withdrawn registration or offering shall be borne by the Company in accordance
with Section 8 hereof.

		 	 

		3.4	Underwriting Requirements. In connection with any
underwritten public offering of shares of the Company’s share capital under this Section 3, the Company shall not be required
under this Section ‎3 to include any of the Holders’ securities in such offering unless they accept the terms
of the underwriting as agreed upon between the Company and the underwriters selected by it (or by other persons entitled to select
the underwriters) and enter into an underwriting agreement in customary form with an underwriter or underwriters selected by the
Company, and then only in such quantity as the underwriters determine in their sole discretion will not jeopardize the success
of the offering by the Company based on marketing factors. If the total amount of securities, including Registrable Securities,
requested by shareholders to be included in such offering exceeds the amount of securities sold other than by the Company that
the underwriters determine in their sole discretion is allowed based on marketing factors, then the Company shall be required
to include in the offering only that number of such securities, including Registrable Securities, that the underwriters determine
in their sole discretion will not jeopardize the success of the offering and the Company shall include in such registration, (i)
first, shares which the Company may wish to register for its own account, (ii) second, the Registrable Securities
requested to be included therein by the Holders (the securities so included to be allocated between the Holders on a pro rata
basis based on the number of Registrable Securities held by all such Holders) and (iii) third, other securities
requested to be included in such registration. Notwithstanding the foregoing, in no event shall the number of Registrable Securities
included in the offering be reduced unless all other securities (other than securities to be sold by the Company) are first entirely
excluded from the offering. If any Holder disapproves of the terms of any such underwriting, such Holder may elect to withdraw
therefrom by written notice to the Company and the underwriter, delivered at least twenty (20) days prior to the effective date
of the registration statement. Any Registrable Securities excluded or withdrawn from such underwriting shall be excluded and withdrawn
from the registration.

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		3.5	Subject to Section 12 below, there shall be no limit on
the number of times that a Holder may request registration of Registrable Securities under this Section 3, and registrations
effected pursuant to this Section 3 shall not be counted as requests for registration effected pursuant to Section 2.

		 	 

		4.	Form F-3 Registration.

		 	 

		4.1	In case the Company shall receive from the Initiating
Holders a written request or requests (each, a “Form F-3 Request Notice”) that the Company effect a registration
on Form F-3, at a time when the Company is eligible to register securities for a secondary offering by its stockholders
on the SEC’s Form F-3 (or any successor form to Form F-3, regardless of its designation), the Company shall within ten (10)
days after receipt of any such request, give written notice of the proposed registration, and any related qualification or compliance,
to all other Holders; and use its best efforts to effect, as soon as practicable, such registration and all such qualifications
and compliances as may be so requested and as would permit or facilitate the sale and distribution of all or such portion of such
Holders’ Registrable Securities as are specified in such request, together with all or such portion of the Registrable Securities
of any other Holders joining in such request as are specified in a written request given within fifteen (15) days after receipt
of such written notice from the Company. All written requests from any Holder or Holders to effect a registration on Form F-3
pursuant to this Section 4 shall indicate whether such Holder(s) intend to effect the offering promptly following effectiveness
of the registration statement or whether, pursuant to this Section 4, they intend for the registration statement to remain effective
so that they may effect the offering on a delayed basis (a “Shelf Request”).

		 	 

		4.2	In the event a Form F-3 is filed pursuant to a Shelf Request,
upon a written request (a “Form F-3 Demand Notice”) from any Holder or Holders that are entitled to sell securities
pursuant to such Form F-3 without filing a post-effective amendment that the Company effect an offering with respect to Registrable
Securities (a “Takedown”), the Company will, as soon as practicable, (x) deliver a notice relating to the proposed
Takedown to all other Holders who are named or are entitled to be named as a selling shareholder in such Form F-3 without filing
a post-effective amendment thereto and (y) promptly (and in any event not later than twenty (20) days after receiving such request)
supplement the prospectus included in the Shelf Registration Statement as would permit or facilitate the sale and distribution
of all or such portion of the initiating Holders’ Registrable Securities as are specified in such Form F-3 Demand Notice
together with the other Registrable Securities requested to be included in such Takedown by any other Holders who notify the Company
in writing within ten (10) Business Days after receipt of such notice from the Company.

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		4.3	Notwithstanding the foregoing, the Company shall not be
obligated to effect any such registration, qualification or compliance pursuant to a Form F-3 Request Notice under Section 4.1
or to file a prospectus supplement pursuant to a Form F-3 Demand Notice for a Takedown under Section ‎4.2 (as applicable):

 

		(a)	if Form F-3 is not available for such offering
by the Holders;

		 	 

		(b)	if the Holders, together with the holders of any other
securities of the Company entitled to inclusion in such registration or such Takedown (as applicable), propose to sell Registrable
Securities and such other securities (if any) at an anticipated aggregate price to the public (net of any underwriters’
discounts or commissions) of less than $1,000,000;

		 	 

		(c)	if the Company has, within the twelve (12) month
period preceding the date of such request, already effected two registrations on Form F-3 for the Holders pursuant to
Section ‎4.1 or two Takedowns under Section 4.2 (as applicable); or

		 	 

		(d)	in any particular jurisdiction in which the Company would
be required to qualify to do business or to execute a general consent to service of process in effecting such registration, qualification
or compliance; it being understood that if the Company has registered its securities in a certain state in the United States in
which a registration is required pursuant to this Section 4 – it will not be able to excuse itself from the request based
on this exclusion.

 

		4.4	Subject to the foregoing, the Company shall file a registration
statement or prospectus supplement covering the Registrable Securities and other securities so requested to be registered as soon
as practicable after receipt of the request or requests of the Holders. Registrations effected pursuant to this Section ‎4
shall not be counted as requests for registration effected pursuant to Section ‎2 and there shall be no limit on such
requests.

 

		5.	Obligations of the Company.

 

Whenever
required under this Agreement to effect the registration of any Registrable Securities, the Company shall, as expeditiously as
reasonably possible:

 

		5.1	prepare and file with the SEC a registration statement
with respect to such Registrable Securities and use its best commercial efforts to cause such registration statement to become
effective, and, upon the request of the Holders holding a majority of the Registrable Securities registered thereunder, keep such
registration statement effective for a period of up to (i) one hundred eighty (180) days, (ii) in the event of a Form F-3 registration,
for a period of up to two hundred and seventy (270) days or, (iii) in either case, if earlier, until the distribution contemplated
in the Registration Statement has been completed;

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		5.2	prepare and file with the SEC such amendments and supplements
to such registration statement and the prospectus used in connection with such registration statement as may be necessary to comply
with the provisions of the Act with respect to the disposition of all securities covered by such registration statement;

		 	 

		5.3	furnish to the Holders such numbers of copies of a prospectus,
including a preliminary prospectus, in conformity with the requirements of the Act, and such other documents as they may reasonably
request in order to facilitate the disposition of Registrable Securities owned by them;

		 	 

		5.4	use its best efforts to register and qualify the securities
covered by such registration statement under such other securities or Blue Sky laws of such jurisdictions as shall be requested
by the Holders, provided that the Company shall not be required in connection therewith or as a condition thereto to qualify to
do business or to file a general consent to service of process in any such states or jurisdictions;

		 	 

		5.5	in the event of any underwritten public offering, enter
into and perform its obligations under an underwriting agreement, in usual and customary form, with the managing underwriter of
such offering;

		 	 

		5.6	notify each Holder of Registrable Securities covered by
such registration statement at any time when a prospectus relating thereto is required to be delivered under the Act or the happening
of any event as a result of which the prospectus included in such registration statement, as then in effect, includes an untrue
statement of a material fact or omits to state a material fact required to be stated therein or necessary to make the statements
therein not misleading in the light of the circumstances then existing;

		 	 

		5.7	cause all such Registrable Securities registered pursuant
hereunder to be listed on each securities exchange on which similar securities issued by the Company are then listed;

		 	 

		5.8	provide a transfer agent and registrar for all Registrable
Securities registered pursuant hereunder and a CUSIP number for all such Registrable Securities, in each case not later than the
effective date of such registration;

		 	 

		5.9	furnish, at the request of any Holder requesting registration
of Registrable Securities pursuant to this Agreement, on the date that such Registrable Securities are delivered to the underwriters
for sale in connection with a registration pursuant to this Agreement, if such securities are being sold through underwriters,
or, if such securities are not being sold through underwriters, on the date that the registration statement with respect to such
securities becomes effective, (i) an opinion, dated such date, of the counsel representing the Company for the purposes of such
registration, in form and substance as is customarily given to underwriters in an underwritten public offering, addressed to the
underwriters, if any, and to the Holders requesting registration of Registrable Securities and (ii) a letter dated such date,
from the independent certified public accountants of the Company, in form and substance as is customarily given by independent
certified public accountants to underwriters in an underwritten public offering, addressed to the underwriters, if any, and to
the Holders requesting registration of Registrable Securities.

 

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		6.	Deferral or Suspension.  Notwithstanding
the provisions of Sections 2 through 5, if the Company shall furnish to Holders requesting the filing of a registration statement
or the undertaking of an offering a certificate signed by the Chief Executive Officer or Chairman
of the Board of Directors of the Company stating that in the good faith judgment of the Board, it would be materially detrimental
to the Company and its shareholders for such registration statement to be filed or offering to be undertaken, for instance, as
it would (i) materially interfere with a significant acquisition, corporate reorganization,
or other similar transaction involving the Company; (ii) require premature disclosure of material information that the Company
has a bona fide business purpose for preserving as confidential; or (iii) render the Company unable to comply with requirements
under applicable securities laws, then the Company shall have the right to defer the filing of a registration statement or suspend
the use of a registration statement; provided, however, that in any twelve (12)
month period, the Company may utilize this right (a) not more than once, and (b) for
a period of not more than ninety (90) days.

		 	 

		7.	Information from Holder. It shall be a condition
precedent to the obligations of the Company to take any action pursuant to this Agreement with respect to the Registrable Securities
of any selling Holder that such Holder shall furnish to the Company such information regarding itself, the Registrable Securities
held by it, and the intended method of disposition of such securities as shall be reasonably requested in writing by the Company
and as shall be required in accordance with applicable law to effect the registration of such Holder’s Registrable Securities,
and with respect to any underwritten registration hereunder that such Holder completes and executes all questionnaires and powers
of attorney, indemnities, underwriting agreements, and other documents required under the terms of such underwriting arrangements
to which such Holder is subject to in accordance with the terms hereof.

		 	 

		8.	Expenses of Registration. Except for underwriting
discounts and commissions (which shall be borne by the Holders pro rata based upon the number of Registrable Securities that are
included in the registration) all expenses incurred in connection with registrations, filings or qualifications pursuant to Sections ‎2,
‎3 and ‎4, including (without limitation) all registration, filing and qualification fees, printers’ and accounting
fees, fees and disbursements of counsel for the Company and the reasonable fees and disbursements of one counsel for the selling
Holders, shall be borne by the Company. Notwithstanding the foregoing, the Company shall not be required to pay for any expenses
of any registration proceeding begun pursuant to Section ‎2 or Section ‎4 if the registration request is
subsequently withdrawn at the request of the Holders holding a majority of the Registrable Securities to be registered (in which
case all participating Holders shall bear such expenses pro rata based upon the number of Registrable Securities that were to
be requested in the withdrawn registration), unless, in the case of a registration requested under Section ‎2, the
Holders holding a majority of the Registrable Securities agree to forfeit their right to one demand registration pursuant to Section ‎2;
provided, however, that if at the time of such withdrawal, the Holders have learned of a material adverse change in the condition,
business, or prospects of the Company from that known to the Holders at the time of their request and have withdrawn the request
with reasonable promptness following disclosure by the Company of such material adverse change, or if such withdrawal is based
on the advice of the managing underwriter due to an adverse change in the condition, business, or prospects of the Company, in
each case the Holders shall not be required to pay any of such expenses and shall retain their rights pursuant to Section ‎2
or ‎4 (e.g. such registrations shall not be counted on account of demand registration).

    	11

    	 

    

		9.	Indemnification. In the event any Registrable Securities
are included in a registration statement under this Agreement:

 

		9.1	To the extent permitted by law, the Company will indemnify
and hold harmless each Holder, the partners, members or officers, directors and shareholders of each Holder, any underwriter (as
defined in the Act) for such Holder and each person, if any, who controls such Holder or underwriter within the meaning of the
Act or the 1934 Act (a “Holder Indemnitee”), against any losses, claims, damages or liabilities (joint or several)
to which they may become subject under the Act, the 1934 Act or any state securities laws, insofar as such losses, claims, damages,
or liabilities (or actions in respect thereof) arise out of or are based upon any of the following statements, omissions or violations
(collectively a “Violation”): (i) any untrue statement or alleged untrue statement of a material fact
contained in such registration statement, including any preliminary prospectus or final prospectus contained therein or any amendments
or supplements thereto or any disclosure package filed with the SEC, (ii) the omission or alleged omission to state therein
a material fact required to be stated therein, or necessary to make the statements therein not misleading, or (iii) any violation
or alleged violation by the Company of the Act, the 1934 Act, any state securities laws or any rule or regulation promulgated
under the Act, the 1934 Act or any state securities laws; and the Company will reimburse each such Holder Indemnitee promptly
upon demand for any legal or other expenses reasonably incurred by them in connection with investigating or defending any such
loss, claim, damage, liability or action; provided, however, that the indemnity agreement contained in this subsection ‎9.1
shall not apply to amounts paid in settlement of any such loss, claim, damage, liability or action if such settlement is effected
without the consent of the Company (which consent shall not be unreasonably withheld), nor shall the Company be liable in any
such case to a Holder Indemnitee for any such loss, claim, damage, liability or action to the extent that it arises out of or
is based upon a Violation that occurs in reliance upon and in conformity with written information furnished expressly for use
in connection with such registration statement by such Holder Indemnitee; provided further, however, that the foregoing
indemnity agreement insofar as they relate to any preliminary prospectus shall not inure to the benefit of any Holder Indemnitee,
from whom the person asserting any such losses, claims, damages or liabilities purchased shares in the offering, if a copy of
the prospectus (as then amended or supplemented if the Company shall have furnished any amendments or supplements thereto) was
not sent or given by or on behalf of such Holder Indemnitee, if required by law so to have been delivered, at or prior to the
written confirmation of the sale of the shares to such person, and if the prospectus (as so amended or supplemented) would have
cured the defect giving rise to such loss, claim, damage or liability. Such indemnity shall
remain in full force and effect regardless of any investigation made by or on behalf of the Holder Indemnitee.

    	12

    	 

    

		9.2	To the extent permitted by law, each selling Holder will
severally and not jointly, indemnify and hold harmless the Company, each of its directors, each of its officers, each person,
if any, who controls the Company within the meaning of the Act, any underwriter, any other Holder selling securities in such registration
statement and any controlling person of any such underwriter or other Holder, against any losses, claims, damages or liabilities
(joint or several) to which any of the foregoing persons may become subject, under the Act, the 1934 Act or any state securities
laws, insofar as such losses, claims, damages or liabilities (or actions in respect thereto) arise out of or are based upon any
Violation, in each case to the extent (and only to the extent) that such Violation occurs in reliance upon and in conformity with
written information furnished by such Holder expressly for use in connection with such registration statement; and each such Holder
will reimburse any person intended to be indemnified pursuant to this subsection ‎9.2, for any legal or other expenses reasonably
incurred by such person in connection with investigating or defending any such loss, claim, damage, liability or action; provided,
however, that the indemnity agreement contained in this subsection ‎9.2 shall not apply to amounts paid in settlement
of any such loss, claim, damage, liability or action if such settlement is effected without the consent of the Holder (which consent
shall not be unreasonably withheld); provided further that in no event shall any indemnity under this subsection ‎9.2
exceed the net proceeds from the offering received by such Holder.

		 	 

		9.3	Promptly after receipt by an indemnified party under this
Section ‎8 of notice of the commencement of any action (including any governmental action) involving the subject matter
of the foregoing indemnity provisions, such indemnified party will, if a claim in respect thereof is to be made against any indemnifying
party under this Section ‎8, deliver to the indemnifying party a written notice of the commencement thereof and the
indemnifying party shall have the right to participate in, and, to the extent the indemnifying party so desires, jointly with
any other indemnifying party similarly noticed, to assume the defense thereof with counsel mutually satisfactory to the parties;
provided, however, that an indemnified party (together with all other indemnified parties that may be represented without
conflict by one counsel) shall have the right to retain one separate counsel, with the fees and expenses to be paid by the indemnifying
party, if representation of such indemnified party by the counsel retained by the indemnifying party would be inappropriate due
to actual or potential differing interests between such indemnified party and any other party represented by such counsel in such
proceeding. The failure to deliver written notice to the indemnifying party within a reasonable time of the commencement of any
such action, only if prejudicial to its ability to defend such action, shall relieve such indemnifying party of any liability
to the indemnified party under this Section ‎8 but the omission so to deliver written notice to the indemnifying party
will not relieve it of any liability that it may have to any indemnified party otherwise than under this Section 9. After
notice from the indemnifying party to such indemnified party of its election so to assume the defense thereof, the indemnifying
party will not be liable to such indemnified party pursuant to the provisions of this Section ‎8 for any legal or other
expense subsequently incurred by such indemnified party in connection with the defense thereof, unless (i) the indemnified party
shall have employed counsel in accordance with the provision of the preceding sentence, (ii) the indemnifying party shall not
have employed counsel reasonably satisfactory to the indemnified party to represent the indemnified party within a reasonable
time after the notice of the commencement of the action and within 15 days after written notice of the indemnified party's intention
to employ separate counsel, or (iii) the indemnifying party has authorized the employment of counsel for the indemnified party
at the expense of the indemnifying party. No indemnifying party will consent to entry of any judgment or enter into any settlement,
which does not include as an unconditional term thereof the giving by the claimant or plaintiff to such indemnified party a release
from all liability in respect to such claim or litigation.

    	13

    	 

    

		9.4	If the indemnification provided for in this Section 9
is held by a court of competent jurisdiction to be unavailable to an indemnified party with respect to any loss, liability, claim,
damage or expense referred to herein, then the indemnifying party, in lieu of indemnifying such indemnified party hereunder, shall,
subject to the limitation set forth in this Section ‎9.4, contribute to the amount paid or payable by such indemnified party
as a result of such loss, liability, claim, damage or expense in such proportion as is appropriate to reflect the relative fault
of the indemnifying party on the one hand and of the indemnified party on the other in connection with the statements or omissions
that resulted in such loss, liability, claim, damage or expense, as well as any other relevant equitable considerations. Notwithstanding
anything to the contrary contained herein, in no event shall the contribution obligation of any Holder set forth in this Section
‎9.4 exceed the net proceeds from the offering of Registrable Securities received by such Holder. The relative fault of
the indemnifying party and of the indemnified party shall be determined by reference to, among other things, whether the untrue
or alleged untrue statement of a material fact or the omission to state a material fact relates to information supplied by the
indemnifying party or by the indemnified party and the parties’ relative intent, knowledge, access to information, and opportunity
to correct or prevent such statement or omission.

		 	 

		9.5	Notwithstanding the foregoing, to the extent that the
provisions on indemnification and contribution contained in the underwriting agreement entered into in connection with the underwritten
public offering are in conflict with the foregoing provisions, the provisions in the underwriting agreement shall control.

		 	 

		9.6	The obligations of the Company and Holders under this
Section 9 shall survive the completion of any offering of Registrable Securities in a registration statement under this Agreement,
and otherwise.

 

		10.	Reports Under Securities Exchange Act of 1934.
With a view to making available to the Holders the benefits of Rule 144 promulgated under the Act (“SEC Rule 144”)
and any other rule or regulation of the SEC that may at any time permit a Holder to sell securities of the Company to the public
without registration or pursuant to a registration on Form F-3, the Company agrees to:

 

		10.1	make and keep public information available, as those terms
are understood and defined in SEC Rule 144, at all times after the effective date of the Initial Offering;

		 	 

		10.2	file with the SEC in a timely manner all reports and other
documents required of the Company under the Act and the 1934 Act; and

    	14

    	 

    

		10.3	furnish to any Holder, so long as the Holder owns any
Registrable Securities, forthwith upon request (i) a written statement by the Company that it has complied with the reporting
requirements of SEC Rule 144 (at any time after ninety (90) days after the effective date of the Company’s Initial
Offering), the Act and the 1934 Act (at any time after it has become subject to such reporting requirements), or that it qualifies
as a registrant whose securities may be resold pursuant to Form F-3 (at any time after it so qualifies), (ii) a
copy of the most recent annual or quarterly report of the Company and such other reports and documents so filed by the Company
with the SEC, and (iii) such other information as may be reasonably requested in availing any Holder of any rule or regulation
of the SEC that permits the selling of any such securities without registration or pursuant to such form.

 

		11.	Assignment of Registration Rights. The rights to
cause the Company to register Registrable Securities pursuant to this Agreement may be assigned (but only with all related obligations
and together with the transfer of the related Registrable Securities) (which transfer shall comply with all relevant restrictions
on transfer of securities of the Company under applicable law) by a Holder to any transferee (including a Permitted Transferee)
acquiring or receiving some or all of the Registrable Securities held by a Holder from such Holder; provided: (a) the
Company is, within a reasonable time after such transfer, furnished with written notice of the name and address of such transferee
and the securities with respect to which such registration rights are being assigned; (b) such transferee agrees in writing,
in a form reasonably satisfactory to the Company, to be bound by and subject to the terms and conditions of this Agreement, including
without limitation the provisions of Section 12 below.

		 	 

		12.	“Market Stand-Off” Agreement. (a)
Each Holder hereby agrees that it will not, without the prior written consent of the managing underwriter, during the period commencing
on the date of the final prospectus relating to the Initial Offering and ending on the date specified by the Company and the managing
underwriter, not to exceed one hundred eighty (180) days thereafter, (i) lend, offer, pledge, sell, contract to sell, sell
any option or contract to purchase, purchase any option or contract to sell, grant any option, right or warrant to purchase, or
otherwise transfer or dispose of, directly or indirectly, any Ordinary Shares or any securities convertible into or exercisable
or exchangeable for Ordinary Shares (whether such shares or any such securities are then owned by the Holder or are thereafter
acquired by the Holder during the 180 day period), or (ii) enter into any swap or other arrangement that transfers to another,
in whole or in part, any of the economic consequences of ownership of the Ordinary Shares, whether any such transaction described
in clause (i) or (ii) above is to be settled by delivery of Ordinary Shares or such other securities, in cash or otherwise.
The foregoing provisions of this Section 12 shall only apply to the Initial Offering, shall not apply to the sale of any shares
to an underwriter pursuant to the underwriting agreement for the Initial Offering, and shall be applicable to the Holders if all
officers and directors, and shareholders of the Company holding more than one percent (1%) of the Company’s then existing
fully diluted share capital, enter into similar agreements. Each Holder further agrees to execute such agreements as may be reasonably
requested by the underwriters in the offering to the public (including without limitation, the Initial Offering) that are consistent
with this Section 12 or that are necessary to give further effect thereto. The underwriters are intended third party beneficiaries
of this Section 12 and shall have the right, power and authority to enforce the provisions hereof as though they were a party
hereto.

 

    	15

    	 

    

		(b)	In order to enforce the foregoing restrictions under this
Section 12, the Company may impose stop-transfer instructions with respect to the Registrable Securities of each Holder (and
the shares or securities of every other person subject to the foregoing restrictions) until the end of any such 180 day period.
In addition to the foregoing, no Holder that would be required to sign an agreement restricting its ability to transfer securities
pursuant to this Section 12 shall distribute securities to its shareholders, partners or members after receipt of a Piggyback
Notice or a notice from the Company of its receipt of a Form F-1 Request Notice from Initiating Holders until such time as such
Holder has signed such a “market stand-off” agreement required pursuant hereto.

 

		13.	Limitations on Subsequent Registration Rights.
From and after the date of this Agreement, the Company shall not, without the prior written consent of the Preferred Majority
Holders, enter into any agreement with any holder or prospective holder of any securities of the Company that would allow such
holder or prospective holder to include such securities in any registration filed under this Agreement hereof, unless under the
terms of such agreement, such holder or prospective holder may include such securities in any such registration only to the extent
that the inclusion of such securities will not reduce the amount of the Registrable Securities of the Holders that are included
and shall be subordinated to the rights of any Holder hereunder.

		 	 

		14.	Foreign Offerings. The provisions of this Agreement
shall apply, mutatis mutandis, to any registration of the securities of the Company outside of the United States.

		 	 

		15.	Miscellaneous.

 

		15.1	Successors and Assigns. Except as otherwise provided
herein, the terms and conditions of this Agreement shall inure to the benefit of and be binding upon the respective successors
and assigns of the parties (including transferees of any shares of Registrable Securities). Nothing in this Agreement, express
or implied, is intended to confer upon any party other than the parties hereto or their respective successors and assigns any
rights, remedies, obligations, or liabilities under or by reason of this Agreement, except as expressly provided in this Agreement.

		 	 

		15.2	Governing Law. This Agreement shall be governed
by and construed under the laws of the State of Israel as applied to agreements among Israeli residents entered into and to be
performed entirely within the State of Israel, except that all matters governed by or relating to the federal securities laws
of the United States of America shall be interpreted in accordance with such laws. Any dispute arising under or in relation to
this Agreement shall be resolved by the competent courts in Tel Aviv –Yafo, Israel, and each of the parties hereby submits
exclusively and irrevocably to the jurisdiction of such court.

		 	 

		15.3	Counterparts. This Agreement may be executed in
two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same
instrument.

		 	 

		15.4	Titles and Subtitles. The titles and subtitles
used in this Agreement are used for convenience only and are not to be considered in construing or interpreting this Agreement.

    	16

    	 

    

		15.5	Notices. Any notice required or permitted by any
provision of this Agreement shall be given in writing and shall be delivered personally, by courier, by facsimile, electronic
mail or by registered or certified mail, postage prepaid, addressed (i) in the case of the Company, to its principal office; (ii)
in the case of any Investor that is an original party to this Agreement at the address of such Investor as set forth in the records
of the Company or such other address for such Investor as shall be designated in writing from time to time to such Investor; and,
(iii) in the case of any Permitted Transferee of a party to this Agreement or any other transferee of Registrable Securities to
whom registration rights are assigned pursuant to Section 11, to such Permitted Transferee or other transferee at its address
as designated in writing by such Permitted Transferee or other transferee to the Company from time to time. Notices that are mailed
shall be deemed received five (5) days after deposit in registered or certified mail, return receipt requested. Notices sent by
courier or overnight delivery shall be deemed received two (2) days after they have been so sent. Notices sent by facsimile or
email shall be deemed received on the first Business Day following transmission and electronic confirmation of receipt.

		 	 

		15.6	Entire Agreement; Amendments and Waivers. This
Agreement (including the schedules hereto, if any) constitutes the full and entire understanding and agreement among the parties
with regard to the subjects hereof and thereof. Any term of this Agreement may be amended and the observance of any term of this
Agreement may be waived (either generally or in a particular instance and either retroactively or prospectively) with the written
consent of the Company and the Preferred Majority Holders. Any amendment or waiver effected in accordance with this paragraph
shall be binding upon the Investors, their future transferees and the Company. Notwithstanding the foregoing, to the extent any
amendment to this Agreement adversely affects the rights of a specific Holder hereunder in a manner which discriminates such Holder
against other Holders (taking into account existing differences, including without limitation, in number of Registrable Securities
and/or class thereof), such amendment shall require the written approval of such Holder. For the avoidance of doubt, the following
amendments shall not be deemed to adversely affect a specific Holder: (i) amendments setting minimum holding thresholds for rights
under this Agreement, (ii) amendments to add a new series of preferred shares of the Company to the definitions of Holder, Preferred
Shares, Registrable Securities and/or Investors.

		 	 

		15.7	Severability. If one or more provisions of this
Agreement are held to be unenforceable under applicable law, such provision shall be excluded from this Agreement and the balance
of the Agreement shall be interpreted as if such provision were so excluded and shall be enforceable in accordance with its terms.

		 	 

		15.8	Aggregation of Shares. All Registrable Securities
held or acquired by Permitted Transferees shall be aggregated together for the purpose of determining the availability of any
rights under this Agreement.

 

[Remaining
of page was left intentionally blank]

    	17

    	 

    

 

In Witness Whereof,
the parties hereto have caused this Second Amended and Restated Registration Rights Agreement to be duly executed on the day and
year first above written:

 

	 	/s/ Shai Lankry	 	 	 
	 	Macrocure Ltd.	 	Viola Private Equity I, L.P.	 
	 	By:	Shai Lankry	 	By:	 	 
	 	Title:	Chief Financial Officer	 	Title:	 	 
	 	 	 	 	 	 	 
	 	/s/ Zeev Holender	 	/s/ Tomer Kariv	 
	 	Vaizra Ventures Ltd.	 	Pontifax (Cayman) II L.P.	 
	 	By:	Zeev Holender	 	By:	Tomer Kariv	 
	 	Title:	Diector	 	Title:	 	 
	 	 	 	 	 	 	 	 	 

	 	/s/ Tomer Kariv	 	/s/ Tomer Kariv	 
	 	Pontifax (Israel) II – Individual Investors L.P.	 	Pontifax (Israel) II L.P.	 
	 	By:	Tomer Kariv	 	By:	Tomer Kariv
	 	Title:	 	 	Title:	 
	 	 	 	 	 	 	 	 	 

    	18

    	 

    

Schedule
A

 

INVESTORS

 

		1.	Vaizra Ventures Ltd.

 

		2.	Kuf Dalet (104) Ltd.

 

		3.	Yitzhak (Viatcheslav) Mirilashvili

 

		4.	Viola Private Equity I, L.P.

 

		5.	Pontifax (Israel) II - Individual Investors L.P.

 

		6.	Pontifax (Israel) II L.P.

 

		7.	Pontifax (Cayman) II L.P.

 

		8.	Plan B Ventures I, LLC

 

		9.	Docor International B.V.

 

		10.	Biosec Limited

 

		11.	Yitzhak Goldman

 

		12.	Yair Aloni

 

		13.	Michael Sela

 

		14.	Uriel Arnon

 

		15.	Dov Shafir

 

		16.	Yariv Gilat

 

		17.	H.M.L.K Financial Consulting Services Ltd.

 

		18.	EleganTree Ltd.

 

		19.	Yossef Tzvi Circus

 

		20.	Daniel ReichExhibit 10.8

 

FORM
OF indemnification agreement

 

THIS INDEMNIFICATION AGREEMENT (the “Agreement”),
dated as of ________ __, 2014, is entered into by and between Macrocure Ltd., an Israeli company whose address is 25 Hasivim St.,
Petach Tikva, Israel (the “Company”), and the undersigned Director or Officer of the Company whose
name appears on the signature page hereto officer (the “Indemnitee”).

 

		WHEREAS,	Indemnitee is an Office Holder (“Nosse Misra”),
as such term is defined in the Companies Law, 5759–1999, as amended (the “Companies
Law” and “Office Holder” respectively),
of the Company; 

 

		WHEREAS,	both the Company and Indemnitee recognize the increased risk
of litigation and other claims being asserted against Office Holders of companies and that highly competent persons have become
more reluctant to serve corporations as directors and officers or in other capacities unless they are provided with adequate protection
through insurance or adequate indemnification against inordinate risks of claims and actions against them arising out of their
service to, and activities on behalf of, companies; 

 

		WHEREAS,	the Articles of Association
of the Company authorize the Company to indemnify and advance expenses to its Office Holders and provide for insurance and exculpation
to its Office Holders, in each case, to the fullest extent permitted by applicable law and this Agreement is provided to Indemnitee
in accordance with applicable law, the Articles of the Association of the Company and all requisite corporate approvals;

 

		WHEREAS,	the Company has determined that (i) the increased difficulty
in attracting and retaining competent persons is detrimental to the best interests of the Company’s shareholders and that
the Company should act to assure such persons that there will be increased certainty of such protection in the future, (ii) and
it is reasonable, prudent and necessary for the Company contractually to obligate itself to indemnify, and to advance expenses
on behalf of, such persons to the fullest extent permitted by applicable law, so that they will serve or continue to serve the
Company free from undue concern that they will not be so indemnified; 

 

		WHEREAS,	the Company acknowledges that Indemnitee is relying on the obligations
of the Company set forth in this Agreement in agreeing to serve the Company, which obligations are therefore irrevocable; and

 

		WHEREAS,	in recognition of Indemnitee’s need for substantial protection
against loss arising from the Indemnitee's liability, including costs and expenses incurred by the Indemnitee due to his position
as an Office Holder, in order to assure Indemnitee’s continued service to the Company in an effective manner and, in part,
in order to provide Indemnitee with specific contractual assurance that the indemnification, insurance and exculpation afforded
by the Articles of Association will be available to Indemnitee, the Company wishes to undertake in this Agreement for the indemnification
of and the advancing of expenses to Indemnitee to the fullest extent permitted by applicable law and as set forth in this Agreement
and provide for insurance and exculpation of Indemnitee as set forth in this Agreement.

    	 

    	 

    

 

NOW, THEREFORE, the parties hereto
agree as follows:

 

		1.	INDEMNIFICATION AND INSURANCE.

 

		1.1.	The Company hereby undertakes to indemnify Indemnitee to the fullest extent permitted by applicable
law and the Company's Articles of Association, as each may be amended from time to time, for any liability and expense specified
in Sections ‎1.1.1 through ‎1.1.4 below, imposed on Indemnitee due to or in connection with an act performed by such Indemnitee,
either prior to or after the date hereof, in Indemnitee’s capacity as an Office Holder, including, without limitation, as
a director, officer, employee, agent or fiduciary of the Company, any subsidiary thereof or any other corporation, collaboration,
partnership, joint venture, trust or other enterprise, in which Indemnitee serves at any time at the request of the Company (the
“Corporate Capacity”). The term “act performed in Indemnitee’s capacity as an Office Holder”
shall include, without limitation, any act, omission and failure to act and any other circumstances relating to or arising from
Indemnitee’s service in a Corporate Capacity. Notwithstanding the foregoing, in the event that the Office Holder is the beneficiary
of an indemnification undertaking provided by a subsidiary of the Company or any other entity [(other than a Secondary Indemnitor
(as defined below))],1 with respect to his Corporate
Capacity with such subsidiary or entity, then the indemnification obligations of the Company hereunder with respect to such Corporate
Capacity shall only apply to the extent that the indemnification by such subsidiary or other entity does not actually fully cover
the indemnifiable liabilities and expenses relating thereto. The following shall be hereinafter referred to as “Indemnifiable
Events”:

 

		1.1.1.	Financial liability imposed on Indemnitee in favor of any person pursuant to a judgment, including
a judgment rendered in the context of a settlement or an arbitrator’s award approved by a court. For purposes of Section
‎1 of this Agreement, the term “person” shall include, without limitation, a natural person, firm, partnership,
joint venture, trust, company, corporation, limited liability entity, unincorporated organization, estate, government, municipality,
or any political, governmental, regulatory or similar agency or body;

 

		1.1.2.	Reasonable Expenses (as defined below) expended or incurred by Indemnitee as a result of an investigation
or any proceeding instituted against the Indemnitee by an authority that is authorized to conduct an investigation or proceeding
to the full extent permitted by applicable law.

 

 

1
Only relevant to directors who have an additional indemnification agreement provided by their employers.

 

    	 

    	 

    

 

		1.1.3.	Reasonable Expenses incurred by or charged to Indemnitee by a court, in a proceeding instituted
against him by the Company or on its behalf or by another person, or in a criminal charge from which he was acquitted or in which
he was convicted of an offence that does not require proof of Mens Rea; and

 

		1.1.4.	A financial obligation imposed upon Indemnitee and reasonable Expenses expended Indemnitee as a
result of an administrative proceeding instituted against Indemnitee. Without derogating from the generality of the foregoing,
such obligation or Expense will include a payment which Indemnitee is obligated to make to an injured party as set forth in Section
52(54)(a)(1)(a) of the Israeli Securities Law, 1968 – 5728 (the "Securities Law") and Expenses that Indemnitee
incurred in connection with a proceeding under Chapters H'3, H'4 or I'1 of the Securities Law; and

 

		1.1.5.	Any other event, occurrence, matter or circumstances under any law with respect to which the Company
may, or will be able to, indemnify an Office Holder (including, without limitation, in accordance with Section 56h(b)(1) of the
Israeli Securities Law 5728-1968 (the “Israeli Securities Law”), if applicable, and Section 50P(b)(2)
of the Israeli Restrictive Trade Practices Law, 5758-1988 (the “RTP Law”)).

 

For the purpose of this Agreement,
“Expenses” shall include, without limitation, attorneys’ fees and all other costs, expenses and obligations
paid or incurred by Indemnitee in connection with investigating, defending, being a witness in or participating in (including on
appeal), or preparing to defend, be a witness in or participate in any claim relating to any matter for which indemnification hereunder
may be provided, and costs and expenses paid or incurred by Indemnitee in successfully enforcing this Agreement. Expenses shall
be considered paid or incurred by Indemnitee at such time as Indemnitee is required to pay or incur such cost or expenses, including
upon receipt of an invoice or payment demand. The Company shall pay the Expenses in accordance with the provisions of Section ‎1.3.

 

		1.2.	Notwithstanding anything herein to the contrary, the Company’s undertaking to indemnify the
Indemnitee in advance under Section ‎1.1.1 shall only be with respect to events described in Exhibit A hereto.
The Board of Directors of the Company (the “Board”) has determined that the categories of events listed in Exhibit
A are likely to occur in light of the operations of the Company. The maximum amount of indemnification payable by the Company under
Section ‎1.1.1 of this Agreement with respect to all persons with respect to whom the Company undertook to indemnify under
agreements similar to this Agreement (the “Indemnifiable Persons”), for all events described in Exhibit A, shall
be as set forth in Exhibit A hereto (the “Limit Amount”). If the Limit Amount is insufficient to cover all the
indemnity amounts payable with respect to all Indemnifiable Persons, then such amount shall be allocated to such Indemnifiable
Persons pro rata according to the percentage of their culpability, as finally determined by a court in the relevant claim, or,
absent such determination or in the event such persons are parties to different claims, based on an equal pro rata allocation among
such Indemnifiable Persons. The Limit Amount payable by the Company for each event described in Exhibit A is deemed by the Company
to be reasonable in light of the circumstances. The indemnification provided under Section ‎1.1.1 herein shall not be subject
to the limitations imposed by this Section ‎1.2 and Exhibit A
if and to the extent such limits are no longer required by the Companies Law.

 

    	 

    	 

    

The Company
hereby declares that according to its Articles of Association it is authorized to indemnify the Indemnitee for liability, costs
and expenses arising from events which are not described in Exhibit A, and it undertakes to consider any request made by the Indemnitee
for such indemnification in accordance with the intent and purpose of this Agreement.

 

		1.3.	If so requested by Indemnitee, and subject to the Company’s repayment and reimbursements
rights set forth in Sections ‎3 and ‎5 below, the Company shall pay amounts to cover Indemnitee’s Expenses with respect
to which Indemnitee is entitled to be indemnified under Section ‎1.1 above, as and when incurred. The payments of such amounts
shall be made by the Company directly to the Indemnitee’s legal and other advisors, as soon as practicable, but in any event
no later than fifteen (15) days after written demand by such Indemnitee therefor to the Company, and any such payment shall be
deemed to constitute indemnification hereunder. All amounts paid as indemnification hereunder shall be grossed-up to cover any
tax payment that Indemnitee may be required to make if the indemnification payments are taxable, subject to the Limit Amount if
required by applicable law. As part of the aforementioned undertaking, the Company will make available to Indemnitee any security
or guarantee that Indemnitee may be required to post in accordance with an interim decision given by a court, governmental or administrative
body, or an arbitrator, including for the purpose of substituting liens imposed on Indemnitee’s assets.

 

		1.4.	The Company’s obligation to indemnify Indemnitee and advance Expenses in accordance with
this Agreement shall apply to any actual, possible or threatened claim, action, suit, demand or proceeding or any inquiry or investigation,
whether civil, criminal or investigative, arising out of the Indemnitee’s service in the Corporate Capacity as described
in Section ‎1.1 above, whether or not Indemnitee is still serving in such position.

 

		1.5.	Without derogating from the Company’s obligations to indemnify Indemnitee as provided herein,
the Company undertakes that, subject to the mandatory limitations under applicable law, as long as it may be obligated to provide
indemnification and advance Expenses under this Agreement and as long as the Indemnitee is exposed to any actual or potential claim,
action, suit, demand, proceeding or any inquiry or investigation, due to the Indemnitee's position as an Office Holder, the Company
will purchase and maintain in effect directors and officers liability insurance, which will include coverage for the benefit of
the Indemnitee, providing coverage in amounts as determined by the Board. The Company hereby undertakes to notify the Indemnitee
30 days prior to the expiration or termination of the directors' and officers’ liability insurance.

 

    	 

    	 

    

		1.6.	Without derogating from the Company’s obligations to indemnify Indemnitee as provided herein,
the Company undertakes to give prompt written notice of the commencement of any claim hereunder to the insurers in accordance with
the procedures set forth in each of the policies. The Company shall thereafter diligently take all actions reasonably necessary
under the circumstances to cause such insurers to pay, on behalf of Indemnitee, all amounts payable as a result of such action,
suit, proceeding, inquiry or investigation in accordance with the terms of such policies. The above shall not derogate from Company’s
authority to freely negotiate or reach any compromise with the insurer which is reasonable at the Company’s sole discretion
provided that the Company shall act in good faith and in a diligent manner.

 

Despite the
above, the Company shall not reach a compromise which releases the insurer from its duty to reimburse the Indemnitee for Expenses
which Indemnitee personally incurred, without the Indemnitee's prior written approval.

 

		1.7.	In making a determination with respect to entitlement to indemnification hereunder, the person
or persons or entity making such determination shall presume that Indemnitee is entitled to indemnification under this Agreement
if Indemnitee has requested it, and the Company shall have the burden of proof to overcome that presumption in connection with
the making of any determination contrary to that presumption.

 

		2.	SPECIFIC LIMITATIONS ON INDEMNIFICATION.

 

Notwithstanding anything to
the contrary in this Agreement, the Company shall not indemnify or advance Expenses to Indemnitee with respect to (i) any act,
event or circumstance with respect to which it is prohibited to do so under applicable law, or (ii) a counter claim made by the
Company or in its name in connection with a claim against the Company filed by the Indemnitee.

 

		3.	REPAYMENT OF EXPENSES.

 

		3.1.	In the event that the Company provides or is required to provide indemnification with respect to
Expenses hereunder and at any time thereafter the Company determines, based on advice from its legal counsel, that the Indemnitee
was not entitled to such payments, the amounts so indemnified by the Company will be promptly repaid by Indemnitee, unless the
Indemnitee disputes the Company’s determination, in which case the Indemnitee’s obligation to repay to the Company
shall be postponed until such dispute is resolved by a court of competent jurisdiction in a final and non-appealable order.

 

		3.2.	Indemnitee’s obligation to repay to the Company for any Expenses or other sums paid hereunder
shall be deemed as a loan given to Indemnitee by the Company subject to the minimum interest rate prescribed by Section 3(9) of
the Income Tax Ordinance [New Version], 1961, or any other legislation replacing it, which is not considered a taxable benefit.

 

    	 

    	 

    

		4.	SUBROGATION.

 

		4.1.	[Except as set forth in Section ‎4.2 below,] In the event of payment under this Agreement,
the Company shall be subrogated to the extent of such payment to all of the rights of recovery of Indemnitee, who shall execute
all documents required and shall do everything that may be necessary to secure such rights, including the execution of such documents
necessary to enable the Company effectively to bring suit to enforce such rights.

 

		4.2.	[The Company hereby acknowledges that Indemnitee has certain rights to indemnification, advancement
of Expenses and/or insurance provided by [venture capital fund] OR [parent company of the Company] OR [shareholder(s) of the Company]
and certain of [its]/[their] affiliates] (collectively, the “Secondary Indemnitors”). The Company hereby agrees (i)
that it is the indemnitor of first resort (i.e., its obligations to Indemnitee are primary and any obligation of the Secondary
Indemnitors to advance Expenses or to provide indemnification for the same Expenses or liabilities incurred by Indemnitee are secondary),
(ii) that it shall be required to advance the full amount of Expenses incurred by Indemnitee and shall be liable for the full amount
of all Expenses, judgments, penalties, fines and amounts paid in settlement to the extent legally permitted and as required by
the terms of this Agreement and the Articles of Association of the Company (or any other agreement between the Company and Indemnitee),
without regard to any rights Indemnitee may have against the Secondary Indemnitors, and, (iii)that it irrevocably waives, relinquishes
and releases the Secondary Indemnitors from any and all claims against the Secondary Indemnitors for contribution, subrogation
or any other recovery of any kind in respect thereof. The Company further agrees that no advancement or payment by the Secondary
Indemnitors on behalf of Indemnitee with respect to any claim for which Indemnitee has sought indemnification from the Company
shall affect the foregoing and the Secondary Indemnitors shall have a right of contribution and/or be subrogated to the extent
of such advancement or payment to all of the rights of recovery of Indemnitee against the Company. The Company and Indemnitee agree
that the Secondary Indemnitors are express third party beneficiaries of the terms of this Section ‎4.2.]

 

		5.	REIMBURSEMENT.

 

[Except as set forth in Section
‎4.2 above,] The Company shall not be liable under this Agreement to make any payment in connection with any Indemnifiable
Event to the extent Indemnitee has otherwise actually received payment under any insurance policy or otherwise (without any obligation
of Indemnitee to repay any such amount) of the amounts otherwise indemnifiable hereunder. Any amounts paid to Indemnitee under
such insurance policy or otherwise after the Company has indemnified Indemnitee for such liability or Expense shall be repaid to
the Company promptly upon receipt by Indemnitee, in accordance with the terms set forth in Section ‎3.2.

 

		6.	EFFECTIVENESS.

 

The Company represents and
warrants that this Agreement is valid, binding and enforceable in accordance with its terms and was duly adopted and approved by
the Company, and shall be in full force and effect immediately upon its execution.

    	 

    	 

    

 

		7.	NOTIFICATION AND DEFENSE OF CLAIM.

 

Indemnitee shall notify the
Company of the commencement of any action, suit or proceeding, and of the receipt of any notice or threat that any such legal proceeding
has been or shall or may be initiated against Indemnitee (including any proceedings by or against the Company and any subsidiary
thereof), promptly upon Indemnitee first becoming so aware; but the omission so to notify the Company will not relieve the Company
from any liability which it may have to Indemnitee under this Agreement unless and to the extent that such failure to provide notice
materially and adversely prejudices the Company’s ability to defend such action. Notice to the Company shall be directed
to the Chief Executive Officer or Chief Financial Officer of the Company at the address shown in the preamble to this Agreement
(or such other address as the Company shall designate in writing to Indemnitee). With respect to any such action, suit or proceeding
as to which Indemnitee notifies the Company of the commencement thereof and without derogating from Sections ‎1.1 and ‎2:

 

		7.1.	Subject to Section 7.2, the Company will be entitled to participate therein at its own expense.

 

		7.2.	Except as otherwise provided below, the Company, alone or jointly with any other indemnifying party
similarly notified, will be entitled to assume the defense thereof, with counsel selected by the Company which counsel is reasonably
reputable with experience in the relevant field. In such case, the fees and expenses of such counsel shall be paid by the Company.
Indemnitee shall have the right to employ his or her own counsel in such action, suit or proceeding, but the fees and expenses
of such counsel incurred after notice from the Company of its assumption of the defense thereof shall be at the expense of Indemnitee,
unless: (i) the employment of counsel by Indemnitee has been authorized in writing by the Company; (ii) Indemnitee reasonably
claims that there may be a conflict of interest between the Company and Indemnitee in the conduct of the defense of such action;
or (iii) the Company has not in fact employed counsel to assume the defense of such action, in which case the reasonable fees
and expenses of counsel shall be at the expense of the Company. The Company shall not be entitled to assume the defense of any
action, suit or proceeding brought by or on behalf of the Company or as to which Indemnitee shall have reached the conclusion specified
in (ii) above.

 

		7.3.	The Company shall not be liable to indemnify Indemnitee under this Agreement for any amounts or
expenses paid in connection with a settlement of any action, claim or otherwise, effected without the Company’s prior written
consent.

 

		7.4.	Without derogating from Section 7.2, the Company shall have the right to conduct the defense as
it sees fit in its sole discretion (provided that the Company shall conduct the defense in good faith and in a diligent manner),
including the right to settle or compromise any claim or to consent to the entry of any judgment against Indemnitee without the
consent of the Indemnitee, provided that, the amount of such settlement, compromise or judgment does not exceed the Limit Amount
(if applicable) and is fully indemnifiable pursuant to this Agreement (subject to Section ‎1.2 of this Agreement) and/or applicable
law, and any such settlement, compromise or judgment does not impose any penalty or limitation on Indemnitee without the Indemnitee’s
prior written consent. The Indemnitee’s consent shall not be required if the settlement includes a complete release of Indemnitee,
does not contain any admission of wrong-doing by Indemnitee, and includes monetary sanctions only as provided above. In the case
of criminal proceedings the Company and/or its legal counsel will not have the right to plead guilty or agree to a plea-bargain
in the Indemnitee’s name without the Indemnitee’s prior written consent. Neither the Company nor Indemnitee will unreasonably
withhold or delay their consent to any proposed settlement.

 

    	 

    	 

    

		7.5.	Indemnitee shall fully cooperate with the Company and shall give the Company all information and
access to documents, files and to his advisors and representatives as shall be within Indemnitee’s power, in every reasonable
way as may be required by the Company with respect to any claim which is the subject matter of this Agreement and in the defense
of other claims asserted against the Company (other than claims asserted by Indemnitee), provided that the Company shall cover
all expenses, costs and fees incidental thereto such that the Indemnitee will not be required to pay or bear such expenses, costs
and fees.

 

		8.	EXCULPATION.

 

Subject to the provisions of
the Companies Law, the Company hereby releases, in advance, the Office Holder from liability to the Company for any damage that
arises from the breach of the Office Holder’s duty of care to the Company (within the meaning of such terms under Sections
252 and 253 of the Companies Law), other than breach of the duty of care towards the Company in a distribution (as such term is
defined in the Companies Law).

 

		9.	NON-EXCLUSIVITY.

 

The rights of the Indemnitee
hereunder shall not be deemed exclusive of any other rights Indemnitee may have under the Company’s Articles of Association,
applicable law or otherwise, and to the extent that during the Indemnification Period the indemnification rights of the then serving
directors and officers are, in any way, in whole or in part, are more favorable to such Indemnitee than the indemnification rights
provided under this Agreement to Indemnitee, Indemnitee shall be entitled to the full benefits of such more favorable indemnification
rights to the extent permitted by law.

 

		10.	PARTIAL INDEMNIFICATION.

 

If Indemnitee is entitled under
any provision of this Agreement to indemnification by the Company for some or a portion of the Expenses, judgments, fines or penalties
actually or reasonably incurred by Indemnitee in connection with any proceedings, but not, however, for the total amount thereof,
the Company shall nevertheless indemnify Indemnitee for the portion of such Expenses, judgments, fines or penalties to which Indemnitee
is entitled under any provision of this Agreement. Subject to the provisions of Section ‎5 above, any amount received by Indemnitee
(under any insurance policy or otherwise) shall not reduce the Limit Amount hereunder and shall not derogate from the Company’s
obligation to indemnify the Indemnitee in accordance with the provisions of this Agreement up to the Limit Amount, as set forth
in Section ‎1.2.

    	 

    	 

    

 

		11.	BINDING EFFECT.

 

This Agreement shall be binding
upon and inure to the benefit of and be enforceable by the parties hereto and their respective successors , permitted assigns (including
any direct or indirect successor in the event of a Transaction) and a receiver, liquidator or the like of the Company, heirs, executors
and personal and legal representatives. In the event of a reorganization, acquisition, change of control merger or consolidation
of the Company or a transfer or disposition of all or substantially all of the business or assets of the Company (each a "Transaction"),
the Company shall, or cause its successor (if applicable) to undertake toward the Indemnitee to, fulfill and honor in all respects
the obligations of the Company pursuant to this Agreement.

 

In the event that the Company
consolidates with or merges into any other entity and shall not be the continuing or surviving company or entity of such consolidation
or merger or transfers or conveys all or a majority of its properties and assets, then, and in each such case, proper provisions
shall be made so that the successors and assigns of the Company, as applicable, shall succeed to the obligations of the Company
set forth in this Section 11.

 

In the event that in connection
with a Transaction the Company purchases a directors and officers’ “tail” or “run-off” policy for
the benefit of its then serving Office Holders, then such policy shall cover Indemnitee and such coverage shall be deemed to be
in satisfaction of the insurance requirements under this Agreement. This Agreement shall continue in effect regardless of whether
Indemnitee continues to serve in a Corporate Capacity.

 

Any amendment to the Companies
Law, the Israeli Securities Law, the RTP Law or other applicable law adversely affecting the right of the Indemnitee to be indemnified,
insured or released pursuant hereto shall be prospective in effect, and shall not affect the Company’s obligation or ability
to indemnify or insure the Indemnitee for any act or omission occurring prior to such amendment, unless otherwise provided by applicable
law.

 

		12.	SEVERABILITY.

 

The provisions of this Agreement
shall be deemed severable and the invalidity or unenforceability of any provision shall not affect the validity or enforceability
of the other provisions hereof. If any provision of this Agreement, or the application thereof or any circumstance, is invalid
or unenforceable, (a) a suitable and equitable provision shall be substituted therefor in order to carry out, so far as may be
valid and enforceable, the intent and purpose of such invalid or unenforceable provision and (b) the remainder of this Agreement
and the application of such provision or circumstances shall not be affected by such invalidity or unenforceability, nor shall
such invalidity or unenforceability affect the validity or enforceability of such provision, or the application thereof, in any
other jurisdiction.

    	 

    	 

    

 

		13.	NOTICE.

 

All notices and other communications
pursuant to this Agreement shall be in writing and shall be deemed provided if delivered personally, telecopied, sent by electronic
facsimile, email, reputable overnight courier or mailed by registered or certified mail (return receipt requested), postage prepaid,
to the parties at the addresses shown in the preamble to this Agreement, or to such other address as the party to whom notice is
to be given may have furnished to the other party hereto in writing in accordance herewith. Any such notice or communication shall
be deemed to have been delivered and received (i) in the case of personal delivery, on the date of such delivery, (ii) in the case
of telecopier or an electronic facsimile or email, one business day after the date of transmission if confirmation of receipt is
received, (iii) in the case of a reputable overnight courier, three business days after deposit with such reputable overnight courier
service, and (iv) in the case of mailing, on the seventh business day following that on which the mail containing such communication
is posted.

 

		14.	GOVERNING LAW; JURISDICTION.

 

This Agreement shall be governed
by and construed and enforced in accordance with the laws of the State of Israel, without giving effect to the conflicts of law
provisions of those laws. The Company and Indemnitee each hereby irrevocably consent to the exclusive jurisdiction and venue of
the courts of Tel Aviv, Israel for all purposes in connection with any action or proceeding which arises out of or relates to this
Agreement.

 

		15.	ENTIRE AGREEMENT AND TERMINATION.

 

This Agreement represents the
entire agreement between the parties and supersedes any other agreements, contracts or understandings between the parties, whether
written or oral, with respect to the subject matter of this Agreement.

 

For the avoidance of doubt,
it is hereby clarified that nothing contained herein derogates from the Company’s right upon its sole discretion, subject
to applicable law and the Articles of Association of the Company, to indemnify Indemnitee post factum for any amounts which Indemnitee
may be obligated to pay as set forth herein without the limitations set forth in Exhibit A below (which limitations, for the
avoidance of doubt, apply only to paragraph 1.1.1).

 

		16.	NO MODIFICATION AND NO WAIVER.

 

No supplement, modification
or amendment, termination or cancellation of this Agreement shall be binding unless executed in writing by both of the parties
hereto. No waiver of any of the provisions of this Agreement shall be deemed or shall constitute a waiver of any other provisions
hereof (whether or not similar) nor shall such waiver constitute a continuing waiver. Any waiver shall be in writing. The Company
hereby undertakes not to amend its Articles of Association in a manner which will adversely affect the provisions of this Agreement.

 

		17.	ASSIGNMENTS; NO THIRD PARTY RIGHTS

 

Neither party hereto may assign
any of its rights or obligations hereunder except with the express prior written consent of the other party. Nothing herein shall
be deemed to create or imply an obligation for the benefit of a third party, other than as provided under Section 4.2 above. Without
limitation of the foregoing, nothing herein shall be deemed to create any right of any insurer that provides directors' and officers’
liability insurance, to claim, on behalf of Indemnitee, any rights hereunder.

 

    	 

    	 

    

		18.	INTERPRETATION; DEFINITIONS.

 

The obligations
of the Company as provided hereunder shall be interpreted broadly and in a manner that shall facilitate its execution, to the extent
permitted by law, and for the purposes for which it was intended.

 

Unless the
context shall otherwise require: words in the singular shall also include the plural, and vice versa; any pronoun shall include
the corresponding masculine, feminine and neuter forms; the words “include”, “includes” and “including”
shall be deemed to be followed by the phrase “without limitation”; the words “herein”, “hereof”
and “hereunder” and words of similar import refer to this Agreement in its entirety and not to any part hereof; all
references herein to Sections or clauses shall be deemed references to Sections or clauses of this Agreement; any references to
any agreement or other instrument or law, statute or regulation are to it as amended, supplemented or restated, from time to time
(and, in the case of any law, to any successor provisions or re-enactment or modification thereof being in force at the time);
any reference to “law” shall include any supranational, national, federal, state, local, or foreign statute or law
and all rules and regulations promulgated thereunder; any reference to a “day” or a number of “days” (without
any explicit reference otherwise, such as to business days) shall be interpreted as a reference to a calendar day or number of
calendar days; reference to month or year means according to the Gregorian calendar; reference to a “company”,
“corporate body” or “entity” shall include a, partnership, firm, company, corporation, limited liability
company, association, joint venture, trust, unincorporated organization, estate, or a government municipality or any political,
governmental, regulatory or similar agency or body, and reference to a “person” shall mean any of the foregoing or
a natural person.

 

		19.	COUNTERPARTS

 

This Agreement may be executed
in any number of counterparts, each of which shall be deemed an original and enforceable against the parties actually executing
such counterpart, and all of which together shall constitute one and the same instrument; it being understood that parties need
not sign the same counterpart. The exchange of an executed Agreement (in counterparts or otherwise) by facsimile or by electronic
delivery in pdf format shall be sufficient to bind the parties to the terms and conditions of this Agreement, as an original.

 

[SIGNATURE PAGE FOLLOWS]

    	 

    	 

    

 

IN WITNESS WHEREOF,
the parties, each acting under due and proper authority, have executed this Indemnification Agreement as of the date first mentioned
above, in one or more counterparts.

 

	Macrocure Ltd.
	By:	 	 
	Name and title:	 	 

	Indemnitee:	 
	Name:	 	 
	Signature:	 	 
	Address:	 

    	 

    	 

    

EXHIBIT
A*

 

	 	CATEGORY OF INDEMNIFIABLE EVENT	LIMIT AMOUNT PER EACH SPECIFIC EVENT WITHIN THIS CATEGORY OF EVENTS
	1.	Claims in connection with employment relationships with and/or by employees of the Company, and in connection with business relations between the Company and its employees, independent contractors, customers, suppliers and various service providers.	The greater of (a) twenty-five percent (25%) of the Company’s total shareholders’ equity according to the Company’s most recent financial statements as of the time of the actual payment of indemnification and (b) $25,000,000 (the “Maximum Amount”)
	2.	Negotiations, execution, delivery and performance of agreements of any kind or nature, anti-competitive acts,acts of commercial wrongdoing, approval of corporate actions including the approval of the acts of the Company’s management, their guidance and their supervision, actions concerning the approval of transactions with Office Holders or shareholders, including controlling persons and claims of failure to exercise business judgment and a reasonable level of proficiency, expertise and care with respect to the Company’s business.  	The Maximum Amount
	3.	Violation, infringement and other misuse of copyrights, patents, designs, trade secrets and any other intellectual property rights, breach of confidentiality obligations, acts in regard of invasion of privacy including with respect to databases or personal information, acts in connection with slander and defamation, and claims in connection with publishing or providing any information, including any filings with any governmental authorities, whether or not required under any applicable laws.	The Maximum Amount
	

    	 

    	 

    

	 	CATEGORY OF INDEMNIFIABLE EVENT	LIMIT AMOUNT PER EACH SPECIFIC EVENT WITHIN THIS CATEGORY OF EVENTS
	4.	Liabilities related to the violation, infringement and other misuse of copyrights, patents, designs, trade secrets and any other intellectual property rights of the Company and/or any Subsidiary and its protection, including the registration or assertion of rights to intellectual property and the defense of claims related to intellectual property. 	The Maximum Amount
	5.	Violations of securities laws of any jurisdiction, including without limitation, fraudulent disclosure claims, failure to comply with any securities authority or any stock exchange disclosure or other rules and any other claims relating to relationships with investors, debt holders, shareholders and the investment community and any claims related to the Sarbanes-Oxley Act of 2002, as amended from time to time; claims relating to or arising out of financing arrangements, any breach of financial covenants or other obligations towards lenders or debt holders of the Company, class actions, violations of laws requiring the Company to obtain regulatory and governmental licenses, permits and authorizations in any jurisdiction; actions taken in connection with the issuance of any type of securities of Company, including, without limitation, the grant of options to purchase any of the same.	The Maximum Amount
	6.	Liabilities arising from the conduct of clinical trials and/or testing, development or manufacturing of products developed or services provided by the Company and/or any Subsidiary or in connection with the distribution, sale, marketing, license or use of such products or services, including without limitations in connection with professional liability and product liability claims.	The Maximum Amount
	7.	The offering of securities by the Company to the public and/or to private investors or the offer by the Company to purchase securities from the public and/or from private investors or other holders pursuant to a prospectus, agreements, notices, reports, tenders and/or other proceedings.	The Maximum Amount
	8.	Events in connection with change in ownership or in the structure of the Company, its reorganization, dissolution, or any decision concerning any of the foregoing, including but not limited to, merger, sale or acquisition of assets, division or change in capital.     	The Maximum Amount
	9.	Any claim or demand made in connection with any transaction not in the ordinary course of business of the Company, including the sale, lease or purchase of any assets or business.	The Maximum Amount

 

    	 

    	 

    

	 	CATEGORY OF INDEMNIFIABLE EVENT	LIMIT AMOUNT PER EACH SPECIFIC EVENT WITHIN THIS CATEGORY OF EVENTS
	10.	Any claim or demand made by any third party suffering any personal injury and/or bodily injury or damage to business or personal property or any other type of damage through any act or omission attributed to the Company, or its employees, agents or other persons acting or allegedly acting on its behalf, including, without limitation, failure to make proper safety arrangements for the Company or its employees and liabilities arising from any accidental or continuous damage or harm to the Company’s employees, its contractors, its guests and visitors as a result of an accidental or continuous event, or employment conditions, permanent or temporary, in the Company’s offices.	The Maximum Amount
	11.	Any claim or demand made directly or indirectly in connection with complete or partial failure, by the Company or its directors, officers and employees, to pay, report, keep applicable records or otherwise, of any foreign, federal, state, county, local, municipal or city taxes or other compulsory payments of any nature whatsoever, including, without limitation, income, sales, use, transfer, excise, value added, registration, severance, stamp, occupation, customs, duties, real property, personal property, capital stock, social security, unemployment, disability, payroll or employee withholding or other withholding, including any interest, penalty or addition thereto, whether disputed or not.	The Maximum Amount
	12.	Any administrative, regulatory, judicial or civil actions orders, decrees, suits, demands, demand letters, directives, claims, liens, investigations, proceedings or notices of noncompliance or violation by any governmental entity or other person alleging potential responsibility or liability (including potential responsibility or liability for costs of enforcement investigation, cleanup, governmental response, removal or remediation, for natural resources damages, property damage, personal injuries or penalties or for contribution, indemnification, cost recovery, compensation or injunctive relief) arising out of, based on or related to (a) the presence of, release, spill, emission, leaning, dumping, pouring, deposit, disposal, discharge, leaching or migration into the environment (each a “Release”) or threatened Release of, or exposure to, any hazardous, toxic, explosive or radioactive substances, wastes or other pollutants, including petroleum or petroleum distillates, asbestos or asbestos-containing material, polychlorinated biphenyls (“PCBs”) or PCB-containing materials or equipment, radon gas, infectious or medical wastes and all other substances or wastes of any nature regulated pursuant to any environmental law, at any location, whether or not owned, operated, leased or managed by the Company or any of its subsidiaries, or (b) circumstances forming the basis of any violation of any environmental law or environmental permit, license, registration or other authorization required under applicable environmental law and/or public health law.	The Maximum Amount

 

    	 

    	 

    

	 	CATEGORY OF INDEMNIFIABLE EVENT	LIMIT AMOUNT PER EACH SPECIFIC EVENT WITHIN THIS CATEGORY OF EVENTS
	13.	Any administrative, regulatory or judicial actions, orders, decrees, suits, demands, demand letters, directives, claims, liens, investigations, proceedings or notices of noncompliance or violation by any governmental entity or other person alleging the failure to comply with any statute, law, ordinance, rule, regulation, order or decree of any governmental entity applicable to the Company or any of its businesses, assets or operations, or the terms and conditions of any operating certificate or licensing agreement.	The Maximum Amount
	14.	Participation and/or non-participation at the Company’s Board meetings, bona fide expression of opinion and/or voting and/or abstention from voting at the Company’s Board meetings.	The Maximum Amount
	15.	Review and approval of the Company’s financial statements, including any action, consent or approval related to or arising from the foregoing, including, without limitations, execution of certificates for the benefit of third parties related to the financial statements.  	The Maximum Amount
	16.	All actions, consents and approvals relating to a distribution of dividends, in cash or otherwise.	The Maximum Amount
	17.	Liabilities arising out of advertising, including misrepresentations regarding the Company's products and unlawful distribution of emails.	The Maximum Amount
	18.	An announcement, a statement, including a position taken, or an opinion or representation made in good faith by the Office Holder in the course of his duties and in conjunction with his duties, whether in public or in private, including during a meeting of the Board of Directors of the Company or any of the committees of the Board of Directors of the Company.	The Maximum Amount
	19.	Money management, management of the Company’s bank accounts in the areas of activity in which the Company is engaged at banks, including foreign currency deposits, securities, loans and credit facilities, credit cards, bank guarantees, letters of credit, consultation agreements concerning investments including with portfolio managers, hedging transactions, options, futures, and the like.	The Maximum Amount

 

    	 

    	 

    

	 	CATEGORY OF INDEMNIFIABLE EVENT	LIMIT AMOUNT PER EACH SPECIFIC EVENT WITHIN THIS CATEGORY OF EVENTS
	20.	Any action or decision in relation to protection of work safety and/or working conditions, including with respect to provisions of the law, procedures or standards as applicable in or outside of Israel with relating to protection of work safety, pertaining, inter alia, to contamination, health protection, production processes, distribution, use, treatment, storage and transportation of certain materials, including in connection with corporal damage, property and environmental damages.	The Maximum Amount
	21.	Any liability arising under any administrative, regulatory, judicial or civil actions orders, decrees, suits, demands, demand letters, directives, claims, liens, investigations, proceedings or notices of noncompliance or violation of Section 50P(b)(2) of the Israeli Restrictive Trade Practices Law, 5758-1988 	The Maximum Amount
	 	Aggregate Limit Amount for all events together: The greater of (a) twenty-five percent (25%) of the Company’s total shareholders’ equity according to the Company’s most recent financial statements as of the time of the actual payment of indemnification and (b) $25,000,000	The Maximum Amount

 
 

		*	Any reference in this Exhibit A to the Company shall include the Company and any entity in which the
Indemnitee serves in a Corporate Capacity.

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