Document:

EX-10.1

Execution Copy

AMENDMENT NO. 6

AMENDMENT NO. 6 dated as of October 15 , 2008 among The Shaw Group Inc. (the
“Borrower”), the subsidiaries of the Borrower listed on the signature pages hereto as
“Guarantors”, the Extending Lenders listed on the signature pages hereto and BNP Paribas, as
administrative agent (in such capacity, the “Agent”).

The Borrower, the “Guarantors” party thereto, the “Lenders” party thereto and the Agent are
parties to a Credit Agreement dated as of April 25, 2005 (as amended by Amendment No. 1 dated as of
October 3, 2005, Amendment No. 2 dated as of February 27, 2006, Amendment No. 3 dated as of June
20, 2006, Amendment No. 4 dated as of October 13, 2006 and Amendment No. 5 dated as of January 14,
2008, and as the same may be further modified and supplemented and in effect from time to time, the
“Credit Agreement”), providing, subject to the terms and conditions thereof, for extensions
of credit (by means of loans and letters of credit) to be made by said lenders to the Borrower.

The parties hereto wish to amend the Credit Agreement as hereinafter set forth and accordingly
hereby agree as follows:

Section 1. Definitions. Except as otherwise defined in this Amendment No. 6, terms
defined in the Credit Agreement are used herein as defined therein.

Section 2. Amendments. Subject to the satisfaction of the conditions precedent
specified in Section 4 below, but effective as of the date hereof, the Credit Agreement shall be
amended as follows:

2.01. References Generally. References in the Credit Agreement (including references
to the Credit Agreement as amended hereby) to “this Agreement” (and indirect references such as
“hereunder”, “hereby”, “herein” and “hereof”) shall be deemed to be references to the Credit
Agreement as amended hereby.

2.02. Definitions. Article I of the Credit Agreement shall be amended by amending the
following definitions (to the extent already included in said Article I) as provided below and
adding the following definitions in the appropriate alphabetical location (to the extent not
already included in said Article I):

“Amendment No. 6” means Amendment No. 6, dated as of October 15, 2008, to this
Agreement.

“Consolidated Fixed Charges Ratio” shall be amended by replacing the reference
therein to “the Facility Termination Date” with a reference to “any Facility Termination
Date”.

“Extended Termination Date” means the sixth anniversary of the Effective Date.

“Extending Lenders” means (a) the Lenders agreeing to the amendment of this
Agreement contemplated by Amendment No. 6 as evidenced by their signatures thereto and (b)
each other Lender agreeing to be an “Extending Lender” hereunder as evidenced by their
signing of an instrument in form and substance acceptable to the Borrower and the Agent in
connection therewith.

“Facility Termination Date” shall be amended to read as follows: “means (a) in
the case of each Non-Extending Lender, the Initial Termination Date and (b) in the case of
each Extending Lender, the Extended Termination Date; or, in each of the cases referred to
in the preceding clauses (a) and (b), any earlier date on which the Aggregate Commitment is
reduced to zero or otherwise terminated pursuant to the terms hereof.”

“Initial Termination Date” means the fifth anniversary of the Effective Date.

“Lenders” shall be amended to read as follows: “means the lending institutions
listed on the signature pages of this Agreement and their respective successors and assigns
and the lending institutions executing a Lender Addendum and their respective successors
and assigns; provided that from and after the Initial Termination Date, upon the
Non-Extending Lenders being paid all amounts owing to them under this Agreement, the
Non-Extending Lenders shall no longer be Lenders.”

“Non-Extending Lenders” means the Lenders that are not Extending Lenders.

“Supplemental Credit Facility” shall be amended by replacing the reference
therein to “Facility Termination Date” with a reference to “Extended Termination Date”.

2.03. Commitments. Section 2.1.1 of the Credit Agreement shall be amended to read as
follows:

“Loan Commitment. From and including the Effective Date and prior to the
Facility Termination Date applicable to it, each Lender severally agrees, on the terms and
conditions set forth in this Agreement, to (i) make Loans to the Borrower and (ii)
participate in Facility LCs issued upon the request of the Borrower, provided that, after
giving effect to the making of each such Loan and the issuance of each such Facility LC (in
each case determined after giving effect to any reductions or increases in Commitments
scheduled to occur on the date on which each such Loan is to be made or such Facility LC is
to be issued), (A) such Lender’s Outstanding Credit Exposure shall not exceed its
Commitment; (B) the sum of the aggregate outstanding principal amount of the Revolving
Credit Loans plus the Financial LC Obligations shall not exceed the Aggregate
Revolving Credit and Financial LC Commitment at any time, (C) the total Revolving Credit
Loans outstanding shall not exceed the Aggregate Revolving Credit Commitment; (D) the
Aggregate Outstanding Credit Exposure shall not exceed the Aggregate Commitment at any time
during any Unrestricted Period; and (E) the Aggregate Outstanding Credit Exposure shall not
exceed the lesser of (1) the Aggregate Commitment and (2) the Borrowing Base at any time
during any Restricted Period (subject to Section 2.2(c)). Subject to the terms of
this Agreement, the Borrower may borrow, repay and reborrow at any time prior to the
Business Day prior to the Extended Termination Date. All Commitments of the Non-Extending
Lenders shall expire on the Initial Termination Date and all Commitments of the Extending
Lenders shall expire on the Extended Termination Date. An Issuer will issue Facility LCs
hereunder on the terms and conditions set forth in Section 2.19.”

2.04. Swing Line Commitment; Voting Rights. Sections 2.1.2(a) and 12.2.2 of the
Credit Agreement shall each be amended by inserting “applicable to it” immediately after “Facility
Termination Date”.

2.05. Required Payments, Termination. Sections 2.2(a) and 2.2(b) of the Credit
Agreement shall be amended to read as follows:

“(a) All Loans, all outstanding Reimbursement Obligations and all other unpaid
Obligations owing to the Non-Extending Lenders shall be paid in full by the Borrower on the
Initial Termination Date and all Loans, all outstanding Reimbursement Obligations and all
other unpaid Obligations owing to the Extending Lenders shall be paid in full by the
Borrower on the Extended Termination Date, in each case except to the extent that such
Obligations are expressly required hereby to be paid on an earlier date.

(b) Subject to Section 2.2(a), each Swing Line Loan shall be paid in full on
the fifth Business Day from the date such Swing Line Loan was made by the Swing Line
Lender.”

2.06. Commitment Fee, Reductions in Aggregate Commitment. Section 2.5(a) of the
Credit Agreement shall be amended to read as follows:

“(a) The Borrower agrees to pay to the Agent for the account of each Lender according
to its Pro Rata Share a commitment fee at a per annum rate equal to the Applicable Fee Rate
on the average daily excess of the Aggregate Commitment over the Aggregate Outstanding
Credit Exposure (other than Swing Line Loans) from the date hereof to and including the
Facility Termination Date applicable to such Lender, payable quarterly in arrears on each
Payment Date hereafter and on each of the Initial Termination Date and the Extended
Termination Date.

and Section 2.5(b) shall be amended by adding the following sentence at the end thereof:

“The Aggregate Commitment and the Aggregate Facility LC Commitment shall each be
automatically reduced on the Initial Termination Date by the aggregate amount of the
Commitments of all of the Non-Extending Lenders.”

2.07. Change in Interest Rate, etc. The last sentence of Section 2.10 of the Credit
Agreement shall be amended to read as follows:

“No Interest Period may begin before and end after the Initial Termination Date or
begin before and end after the Extended Termination Date.”

2.08. Facility LCs. Section 2.19 of the Credit Agreement shall be amended as follows:

(a) Section 2.19.1 of the Credit Agreement shall be amended to read as follows:

“Issuance. The parties hereto acknowledge that on and after the Effective
Date the Existing Facility LCs shall be Facility LCs issued by an Issuer pursuant to this
Agreement. Facility LCs issued hereunder may be issued in any Agreed Currency. Each
Issuer hereby agrees, on the terms and conditions set forth in this Agreement, to issue
Financial Letters of Credit and Performance Letters of Credit (each, a “Facility
LC”) and to renew, extend, increase, decrease or otherwise modify each Facility LC
(“Modify” and each such action, a “Modification”), from time to time from
and including the Effective Date and prior to the fifteenth Business Day prior to the
Extended Termination Date upon the request of the Borrower; provided that immediately after
each such Facility LC is issued or Modified, (i) the aggregate outstanding principal amount
of the Loans plus the aggregate Dollar Amount of the outstanding Financial LC
Obligations shall not exceed the Aggregate Revolving Credit and Financial LC Commitment,
(ii) (1) the Aggregate Outstanding Credit Exposure shall not exceed the Aggregate
Commitment during any Unrestricted Period and (2) the Aggregate Outstanding Credit Exposure
shall not exceed the lesser of (A) the Aggregate Commitment and (B) the Borrowing Base at
any time during any Restricted Period (subject to Section 2.2(c)) and (iii) at no
time prior to the Initial Termination Date may the sum of the aggregate undrawn stated
amount of all outstanding Facility LCs that expire after the fifth Business Day prior to
the Initial Termination Date plus the aggregate amount of the Extending Lenders’ Pro Rata
Shares of all Loans (including Swing Line Loans) exceed the aggregate amount of the
Commitments of all of the Extending Lenders, in the case of each of the preceding clauses
(i), (ii) and (iii), all relevant amounts determined after giving effect to any reductions
or increases in Commitments and Outstanding Credit Exposures scheduled to occur on the date
on which each such Facility LC is issued or Modified. No Facility LC issued on or after
the Effective Date shall have an expiry date later than the fifth Business Day prior to the
Extended Termination Date.”

(b) The following new Section 2.19.14 shall be added immediately after Section 2.19.13 of the
Credit Agreement:

“2.19.14 Termination and Re-allocation of Facility LC Participations on Fifth
Business Day prior to the Initial Termination Date. Notwithstanding anything contained
in this Agreement or any other Loan Document to the contrary, on the fifth Business Day
prior to the Initial Termination Date, the interests and participations of the
Non-Extending Lenders in the Facility LCs outstanding as at the fifth Business Day prior to
the Initial Termination Date shall automatically terminate and (i) from and after the fifth
Business Day prior to the Initial Termination Date, the Non-Extending Lenders shall have no
liability arising from, relating to, in connection with or otherwise in respect of, such
interests and participations or any Facility LCs, and (ii) such interests and
participations in outstanding Facility LCs shall thereupon automatically and without
further action be re-allocated to the extent necessary such that the interests and
participations in such Facility LCs shall be held by the remaining Lenders ratably in
proportion to their respective Pro Rata Shares (determined after giving effect to the
termination of the interests and participations of the Non-Extending Lenders on the fifth
Business Day prior to the Initial Termination Date, with all such terminations of interests
and participations being treated as reductions in Commitments solely for the purposes of
this calculation).”

2.09. Increase of the Commitments. Section 2.21(a) of the Credit Agreement shall be
amended by replacing each reference therein to “Letters of Credit” with a reference to “Facility
LCs”.

2.10. Liens. Section 6.15 of the Credit Agreement shall be amended by adding the
following new clause (j) immediately after clause (i) thereof:

“(j) Liens over cash collateral in an aggregate amount not exceeding $200,000,000
securing payment in respect of Letters of Credit, provided that at each time any such cash
collateral is posted, and immediately after giving effect thereto, the Borrower and its
Subsidiaries shall have unrestricted cash or Cash Equivalent Investments of not less than
$500,000,000, which cash and Cash Equivalent Investments shall be free and clear of all
Liens (other than Liens in favor of the Agent, for the benefit of the Lenders, granted
pursuant to any Collateral Document).”

2.11. Contingent Obligations. Section 6.19(h) of the Credit Agreement shall be
amended to read as follows:

“(h) guaranties by Borrower or any of its Subsidiaries with respect to any
Indebtedness or other obligations of a joint venture or other Person in which the Borrower
or any of its Subsidiaries has an ownership interest if (i) in the case that such joint
venture or other Person is a manufacturer of modular units for the completion of nuclear
facilities in Lake Charles, Louisiana, (x) such Indebtedness and other obligations consist
of (A) obligations to return state, parish and local governmental authorities incentives
received by such joint venture or other Person for doing business and constructing its
manufacturing facility in Lake Charles, Louisiana in an aggregate amount for all such
obligations not to exceed $50,000,000 and (B) principal of and interest on bonds in an
aggregate principal amount not exceeding $70,000,000 issued to finance the construction of
such manufacturing facility, and customary related costs, expenses and indemnities, and (y)
the Borrower and its Subsidiaries are not liable under such guaranties for more than their
proportionate share of any such obligations (determined by reference to the direct and
indirect ownership interests held by the Borrower in such joint venture or other Person) or
(ii) in all other cases, the aggregate amount of such guaranties does not exceed
$20,000,000 at any time outstanding.”

Section 3. Representations and Warranties. The Borrower represents and warrants to
the Lenders that (i) the representations and warranties set forth in Article V of the Credit
Agreement are true and correct on the date hereof as if made on and as of the date hereof (except
to the extent any such representation or warranty is stated to relate solely to an earlier date, in
which case such representation or warranty shall have been true and correct on and as of such
earlier date) and as if each reference in said Article V to “this Agreement” included reference to
this Amendment No. 6 and (ii) on the date hereof, no Default or Unmatured Default has occurred or
is continuing.

Section 4. Conditions Precedent. The amendments set forth in Section 2 hereof and
the releases set forth in Section 5 hereof shall become effective, as of the date hereof, upon:

(i) the execution and delivery of counterparts of this Amendment No. 6 by the
Borrower, the Guarantors (other than Shaw CENTCOM Services, L.L.C.), the Agent and the
Required Lenders (and the Borrower and each Guarantor, by its execution and delivery of
this Amendment No. 6, each hereby confirms and ratifies all of its respective obligations
under the Guaranty, the Security Agreement and the Subordination Agreement with respect to
the amendments effected hereby);

(ii) the Borrower furnishing the following to the Agent each in form and substance
satisfactory to the Agent and with sufficient copies for the Lenders, where appropriate,
executed by the relevant Person:

(a) a copy, certified by the Secretary or Assistant Secretary of the
Borrower, of its by-laws,

(b) a copy, certified by the Secretary or Assistant Secretary of the
Borrower, along with a certificate of good standing and existence from the
Secretary of State of the State of Louisiana, of resolutions of its board of
directors authorizing the execution of this Amendment No. 6,

(c) an incumbency certificate, executed by the Secretary or Assistant
Secretary of the Borrower which shall identify by name and title and bear the
signatures of the Authorized Officers and any other officers or managers of the
Borrower authorized to sign this Amendment No. 6, upon which certificates the Agent
and the Lenders shall be entitled to rely until informed of any change in writing
by the Borrower, and

(d) a written opinion or opinions of counsel to the Borrower and the
Guarantors, addressed to the Lenders and covering such matters as may be required
by Agent, in form and substance reasonably satisfactory to the Agent;

(iii) the Borrower furnishing to the Agent each in form and substance satisfactory to
the Agent, and with sufficient copies for the Lenders, a bring-down certificate executed by
the Secretary or Assistant Secretary of each Guarantor (other than Shaw CENTCOM Services,
L.L.C.), certifying that: (a) the organizational and operative documents of such Guarantor
certified and delivered in connection with the closing of the Credit Agreement on April 25,
2005, the closing of Amendment No. 2 on February 27, 2006, the closing of Amendment No. 4
on October 13, 2006 or the closing of Amendment No. 5 on January 14, 2008, as the case may
be, have not been amended, rescinded or otherwise changed and remain in full force and
effect, (b) the incumbency certificate of such Guarantor certified and delivered in
connection with the closing of the Credit Agreement on April 25, 2005, the closing of
Amendment No. 2 on February 27, 2006, the closing of Amendment No. 4 on October 13, 2006 or
the closing of Amendment No. 5 on January 14, 2008, as the case may be, has not been
amended, rescinded or otherwise changed, and each signatory thereto remains an Authorized
Officer of such Guarantor and is authorized to sign this Amendment No. 6, (c) to the best
knowledge of such Secretary or Assistant Secretary, the good standing certificates
delivered by such Guarantor in connection with the closing of the Credit Agreement on April
25, 2005, the closing of Amendment No. 2 on February 27, 2006, the closing of Amendment No.
4 on October 13, 2006 or the closing of Amendment No. 5 on January 14, 2008, as the case
may be, remain true, correct and complete and that such Secretary or Assistant Secretary
has no knowledge to the contrary thereof and (d) that the copies of the resolutions of the
respective boards of directors, members or managers or any other governing body authorizing
the execution of this Amendment No. 6, as attached to such certificate, are true, correct
and complete and remain in full force and effect; and

(iv) the Agent receiving evidence of the payment by the Borrower of all fees payable
to the Lenders that the Borrower has agreed to pay in connection with this Amendment No. 6.

Section 5. Release of Shaw CENTCOM Services, L.L.C. as a Guarantor and Release of
Security Interest over its Assets. Subject to the satisfaction of the conditions precedent
specified in Section 4 above, but effective as of the date hereof, Shaw CENTCOM Services, L.L.C.
shall be released and discharged from its obligations as a Guarantor under the Loan Documents and
the security interest granted to the Agent under the Security Agreement in and to all of the right,
title and interest in the assets of Shaw CENTCOM Services, L.L.C. shall be released. For the
avoidance of doubt, Section 6.23 of the Credit Agreement shall continue to apply to Shaw CENTCOM
Services, L.L.C. to the extent that Shaw CENTCOM Services, L.L.C. becomes a Material Subsidiary on
or after the date hereof.

Section 6. Miscellaneous. Except as herein provided, the Credit Agreement shall
remain unchanged and in full force and effect. This Amendment No. 6 may be executed in any number
of counterparts, all of which taken together shall constitute one and the same amendatory
instrument and any of the parties hereto may execute this Amendment No. 6 by signing any such
counterpart. This Amendment No. 6 shall be governed by, and construed in accordance with, the law
of the State of New York.

[Remainder of page intentionally blank]

1

IN WITNESS WHEREOF, the parties hereto have caused this Amendment No. 6 to be duly executed
and delivered as of the day and year first above written.

THE SHAW GROUP INC.

By:

Name:

Title:

2

	 	 	 	GUARANTORS:

LANDBANK PROPERTIES, L.L.C.

By its sole member

The LandBank Group, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Assistant Secretary

ARLINGTON AVENUE E VENTURE, LLC

BENICIA NORTH GATEWAY II, L.L.C.

CAMDEN ROAD VENTURE, LLC

CHIMENTO WETLANDS, L.L.C.

GREAT SOUTHWEST PARKWAY VENTURE, LLC

HL NEWHALL II, L.L.C.

JERNEE MILL ROAD, L.L.C.

KATO ROAD II, L.L.C.

KIP I, L.L.C.

LANDBANK BAKER, L.L.C.

MILLSTONE RIVER WETLAND SERVICES, L.L.C.

NORWOOD VENTURE I, L.L.C.

OTAY MESA VENTURES II, L.L.C.

PLATTSBURG VENTURE, L.L.C.

RARITAN VENTURE I, L.L.C.

WHIPPANY VENTURE I, L.L.C.

By their sole member

LandBank Properties, L.L.C.

by its sole member

The LandBank Group, Inc.

By:      

Name: Clifton S. Rankin

Title: Vice President and Assistant Secretary

AMERICAN PLASTIC PIPE AND SUPPLY, L.L.C.

LFG SPECIALTIES, L.L.C.

SO-GLEN GAS CO., LLC

By their sole member

EMCON/OWT, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

SHAW FT. LEONARD WOOD HOUSING, L.L.C.

SHAW BEALE HOUSING, L.L.C.

SHAW HANSCOM HOUSING, L.L.C.

SHAW LITTLE ROCK HOUSING, L.L.C.

SHAW NORTHEAST HOUSING, L.L.C.

SHAW NORTHWEST HOUSING, L.L.C.

By their sole member

Shaw Infrastructure, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

AMERICAN EAGLE COMMUNITIES MIDWEST, LLC

SHAW FT. LEONARD WOOD HOUSING II, L.L.C.

By their sole member

Shaw Ft. Leonard Wood Housing, L.L.C.

By its sole member

Shaw Infrastructure, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

FT. LEONARD WOOD MANAGEMENT COMPANY, L.L.C.

By its sole member

Shaw Ft. Leonard Wood Housing II, L.L.C.

By its sole member

Shaw Ft. Leonard Wood Housing, L.L.C.

By its sole member

Shaw Infrastructure, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

SHAW GBB, LLC

SHAW LIQUID SOLUTIONS, LLC

By their sole member

Shaw Environmental & Infrastructure, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

SHAW GBB INTERNATIONAL, LLC

By its sole member

Shaw GBB, L.L.C.

By its sole member

Shaw Environmental & Infrastructure, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

SELS ADMINISTRATIVE SERVICES, L.L.C.

By its sole member

Shaw Environmental Liability Solutions, L.L.C.

By its sole member

Shaw E & I Investment Holdings, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

SHAW ENVIRONMENTAL LIABILITY SOLUTIONS, L.L.C.

By its sole member

Shaw E & I Investment Holdings, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

HYDRO POWER SOLUTIONS LLC

By its sole member

Shaw California, L.L.C.

By its sole member

Shaw Environmental, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

SHAW CALIFORNIA, L.L.C.

By its sole member

Shaw Environmental, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

BADGER TECHNOLOGY HOLDINGS, L.L.C.

By its sole member

Badger Technologies, L.L.C.

By its sole member

Stone & Webster Process Technology, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

BADGER TECHNOLOGIES, L.L.C.

By its sole member

Stone & Webster Process Technology, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

NUCLEAR TECHNOLOGY SOLUTIONS, L.L.C.

By its sole member

SC Woods, L.L.C.

By its sole member

Stone & Webster, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

SC WOODS, L.L.C.

INTERNATIONAL CONSULTANTS, L.L.C.

STONE & WEBSTER SERVICES, L.L.C.

By their sole member

Stone & Webster, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

STONE & WEBSTER CONSTRUCTION SERVICES, L.L.C.

By its sole member

Stone & Webster Construction, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

SHAW RIO GRANDE HOLDINGS, L.L.C.

By its sole member

Shaw Rio Grande Valley Fabrication & Manufacturing, L.L.C.

By its sole member

Shaw Power Services, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

SHAW RIO GRANDE VALLEY FABRICATION & MANUFACTURING, L.L.C.

By its sole member

Shaw Power Services, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

EDS EQUIPMENT COMPANY, LLC

By its sole member

Shaw Transmission & Distribution Services, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

GREATER BATON ROUGE ETHANOL, L.L.C.

By its sole member

Shaw Biofuels, L.L.C.

By its sole member

Shaw Capital, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

SHAW BIOFUELS, L.L.C.

By its sole member

Shaw Capital, Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

Vice President and Secretary

SHAW MEXICO, L.L.C.

By its sole member

Shaw Americas, L.L.C.

By its sole member

The Shaw Group Inc.

By:      

Name: Clifton S. Rankin

Title: General Counsel and Corporate Secretary

SHAW AMERICAS, L.L.C.

SHAW JV HOLDINGS, L.L.C.

SHAW POWER SERVICES GROUP, L.L.C.

SHAW REMEDIATION SERVICES, L.L.C.

SHAW SERVICES, L.L.C.

By their sole member

The Shaw Group Inc.

By:      

	 	 	 
	Name:

Title:

	 	Clifton S. Rankin

General Counsel and Corporate Secretary

GFM REAL ESTATE LLC

	 	 	 	 	 
	By:	 	__________________________________
	Name:
	 	Clifton S. Rankin
	Title:
	 	Manager

INTEGRATED SITE SOLUTIONS, L.L.C.

SHAW GLOBAL, L.L.C.

	 	 	 	 	 
	By:	 	__________________________________
	Name:
	 	Clifton S. Rankin
	Title:
	 	Vice President and Secretary

B.F. SHAW, INC.

C.B.P. ENGINEERING CORP.

EMCON/OWT, INC.

ENVIROGEN, INC.

FIELD SERVICES, INC.

GHG SOLUTIONS, INC.

MWR, INC.

PIKE PROPERTIES I, INC.

PIKE PROPERTIES II, INC.

PROSPECT INDUSTRIES (HOLDINGS), INC.

SHAW ALASKA, INC.

SHAW ALLOY PIPING PRODUCTS, INC.

SHAW APP TUBELINE, INC.

SHAW BENECO, INC.

SHAW CAPITAL (NEVADA), INC.

SHAW CAPITAL, INC.

SHAW CMS, INC.

SHAW COASTAL, INC.

SHAW CONNEX, INC.

SHAW CONSULTANTS, INC.

SHAW E & I INVESTMENT HOLDINGS, INC.

SHAW ENERGY & CHEMICALS, INC.

SHAW ENERGY & CHEMICALS INTERNATIONAL, INC.

SHAW ENVIRONMENTAL & INFRASTRUCTURE, INC.

SHAW ENVIRONMENTAL & INFRASTRUCTURE INTERNATIONAL, INC.

SHAW ENVIRONMENTAL & INFRASTRUCTURE MASSACHUSETTS, INC.

SHAW ENVIRONMENTAL, INC.

SHAW ENVIRONMENTAL INTERNATIONAL, INC.

SHAW EUROPE, INC.

SHAW FABRICATION & MANUFACTURING, INC.

SHAW FABRICATION & MANUFACTURING INTERNATIONAL, INC.

SHAW FABRICATORS, INC.

SHAW FACILITIES, INC.

SHAW FIELD SERVICES, INC.

SHAW GBB MAINTENANCE, INC.

SHAW GLOBAL ENERGY SERVICES, INC.

SHAW GLOBAL OFFSHORE SERVICES, INC.

SHAW GRP OF CALIFORNIA

SHAW HOME LOUISIANA, INC.

SHAW INDUSTRIAL SUPPLY CO., INC.

SHAW INFRASTRUCTURE, INC.

SHAW INTELLECTUAL PROPERTY HOLDINGS, INC.

SHAW INTERNATIONAL, INC.

SHAW INTERNATIONAL MANAGEMENT SERVICES ONE, INC.

SHAW INTERNATIONAL MANAGEMENT SERVICES TWO, INC.

SHAW MANAGED SERVICES, INC.

SHAW MANAGEMENT SERVICES ONE, INC.

SHAW MID STATES PIPE FABRICATING, INC.

SHAW MORGAN CITY TERMINAL, INC.

SHAW NAPTECH, INC.

SHAW NORTH CAROLINA, INC.

SHAW NUCLEAR SERVICES, INC.

SHAW POWER, INC.

SHAW POWER DELIVERY SYSTEMS, INC.

SHAW POWER INTERNATIONAL, INC.

SHAW POWER SERVICES, INC.

SHAW PROCESS AND INDUSTRIAL GROUP, INC.

SHAW PROCESS FABRICATORS, INC.

SHAW PROJECT SERVICES GROUP, INC.

SHAW PROPERTY HOLDINGS, INC.

SHAW SSS FABRICATORS, INC.

SHAW STONE & WEBSTER PUERTO RICO, INC.

SHAW SUNLAND FABRICATORS, INC.

SHAW T&D COMPANY, INC.

SHAW TRANSMISSION & DISTRIBUTION SERVICES, INC.

SHAW TRANSMISSION & DISTRIBUTION SERVICES INTERNATIONAL, INC.

SHAW TULSA FABRICATORS, INC.

STONE & WEBSTER, INC.

STONE & WEBSTER ASIA, INC.

STONE & WEBSTER CONSTRUCTION, INC.

STONE & WEBSTER HOLDING ONE, INC

STONE & WEBSTER HOLDING TWO, INC.

STONE & WEBSTER INTERNATIONAL, INC.

STONE & WEBSTER INTERNATIONAL HOLDINGS, INC.

STONE & WEBSTER MASSACHUSETTS, INC.

STONE & WEBSTER MICHIGAN, INC.

STONE & WEBSTER PROCESS TECHNOLOGY, INC.

	 	 	 	 	 
	By:	 	__________________________________
	Name:
	 	Clifton S. Rankin
	Title:
	 	Vice President and Secretary

THE LANDBANK GROUP, INC.

	 	 	 	 	 
	By:	 	__________________________________
	Name:
	 	Clifton S. Rankin
	Title:
	 	Vice President and Assistant Secretary

SHAW MAINTENANCE, INC.

	 	 	 	 	 
	By:	 	__________________________________
	Name:
	 	Clifton S. Rankin
	Title:
	 	Secretary

SHAW ENERGY SERVICES, INC.

	 	 	 	 	 
	By:	 	__________________________________
	Name:
	 	Clarence Ray
	Title:
	 	Vice President and Secretary

SHAW CONSTRUCTORS, INC.

	 	 	 	 	 	 	 	 	 
	By:	 	 
	Name:
	 	David C. Voss	 	 	 	 
	Title:	 	Vice President and Assistant Secretary

3

	 	 	 	 	 	 	 	 	 
	By:	 	 
	 
	 	AGENT:	 	 	 	 
	 
	 	BNPPARIBAS, as Agent	 	 	 	 
	 
	 	By:
	 		—	
	 
	 	 	 	 	 	Name:

	 
	 	 	 	 	 	Title:
	 
	 	By:
	 		—	

Name:

Title:

4

EXTENDING LENDERS:

BNP PARIBAS

	 	 	 	 	 
	By:
	 		—	
	   Name:

	   Title:

	By:
	 		—	
	   Name:

	   Title:

	[LENDER]
	 	 	 	 
	By:
	 		—	

Name:

Title:

5EX-10.1

	 	 	 
	To:

	 	Gilead Sciences, Inc.

333 Lakeside Drive

Foster City, CA 94404
	From:

	 	Citibank, N.A.
	Re:

	 	Collared Accelerated Stock Buyback
	Ref. No:

	 	As provided in the Supplemental Confirmation
	Date:

	 	October 21, 2008
	 

	 	

This master confirmation (this “Master Confirmation”), dated as of October 21, 2008 is
intended to set forth certain terms and provisions of certain Transactions (each, a “Transaction”)
entered into from time to time between Citibank, N.A. (“Bank”) and Gilead Sciences, Inc.
(“Counterparty”). This Master Confirmation, taken alone, is neither a commitment by either party
to enter into any Transaction nor evidence of a Transaction. The additional terms of any
particular Transaction shall be set forth in (i) a Supplemental Confirmation in the form of
Schedule A hereto (a “Supplemental Confirmation”), which shall reference this Master Confirmation
and supplement, form a part of, and be subject to this Master Confirmation and (ii) a Trade
Notification in the form of Schedule B hereto (a “Trade Notification”), which shall reference the
relevant Supplemental Confirmation and supplement, form a part of, and be subject to such
Supplemental Confirmation. This Master Confirmation, each Supplemental Confirmation and the
related Trade Notification together shall constitute a “Confirmation” as referred to in the
Agreement specified below.

The definitions and provisions contained in the 2002 ISDA Equity Derivatives Definitions (the
“Equity Definitions”), as published by the International Swaps and Derivatives Association, Inc.,
are incorporated into this Master Confirmation. This Master Confirmation, each Supplemental
Confirmation and the related Trade Notification evidence a complete binding agreement between
Counterparty and Bank as to the subject matter and terms of each Transaction to which this Master
Confirmation, such Supplemental Confirmation and Trade Notification relate and shall supersede all
prior or contemporaneous written or oral communications with respect thereto.

This Master Confirmation, each Supplemental Confirmation and each Trade Notification
supplement, form a part of, and are subject to an agreement in the form of the 1992 ISDA Master
Agreement (Multicurrency-Cross Border) (the “Agreement”) as if Bank and Counterparty had executed
the Agreement on the date of this Master Confirmation (but without any Schedule except for (i) the
election of Loss and Second Method, New York law (without reference to its choice of laws doctrine
other than Title 14 of Article 5 of the New York General Obligations Law) as the governing law and
US Dollars (“USD”) as the Termination Currency and (ii) the election that subparagraph (ii) of
Section 2(c) will not apply to the Transactions and (iii) the election that the “Cross Default”
provisions of Section 5(a)(vi) shall apply to Bank and Counterparty, in each case with a “Threshold
Amount” of USD 100 million; provided that the phrase “or becoming capable at such time of being
declared” shall be deleted from clause (1) of such Section 5(a)(vi)).

The Transactions shall be the sole Transactions under the Agreement. If there exists any ISDA
Master Agreement between Bank and Counterparty or any confirmation or other agreement between Bank
and Counterparty pursuant to which an ISDA Master Agreement is deemed to exist between Bank and
Counterparty, then notwithstanding anything to the contrary in such ISDA Master Agreement, such
confirmation or agreement or any other agreement to which Bank and Counterparty are parties, the
Transactions shall not be considered Transactions under, or otherwise governed by, such existing or
deemed ISDA Master Agreement.

All provisions contained or incorporated by reference in the Agreement shall govern this
Master Confirmation, each Supplemental Confirmation and each Trade Notification except as expressly
modified herein or in the related Supplemental Confirmation.

If, in relation to any Transaction to which this Master Confirmation, a Supplemental
Confirmation and a Trade Notification relate, there is any inconsistency between the Agreement,
this Master Confirmation, any Supplemental Confirmation, any Trade Notification and the Equity
Definitions, the following will prevail for purposes of such Transaction in the order of precedence
indicated: (i) such Trade Notification, (ii) such Supplemental Confirmation; (iii) this Master
Confirmation; (iv) the Agreement; and (v) the Equity Definitions.

1. Each Transaction constitutes a Share Forward Transaction for the purposes of the Equity
Definitions. Set forth below are the terms and conditions that, together with the terms and
conditions set forth in the Supplemental Confirmation and Trade Notification relating to any
Transaction, shall govern such Transaction.

General Terms:

	 	 	 
	Trade Date:

	 	For each Transaction, as set forth in the related Supplemental Confirmation.
	Buyer:

	 	Counterparty
	Seller:

	 	Bank
	Shares:

	 	Common stock, par value $0.001 per share, of Counterparty (Ticker: GILD)
	Exchange:

	 	NASDAQ
	Related Exchange(s):

	 	All Exchanges.
	Prepayment\Variable

Obligation:

	 	

Applicable
	Prepayment Amount:

	 	For each Transaction, as set forth in the related Supplemental Confirmation.
	Prepayment Date:

	 	For each Transaction, as set forth in the related Supplemental Confirmation.

Valuation:

	 	 	 
	Hedge Period:

	 	The period from and including the Trade Date to and including the Hedge

Completion Date.
	Hedge Completion Date::

	 	For each Transaction, as set forth in the related Trade Notification, to be

the Exchange Business Day on which Bank finishes establishing its initial

Hedge Positions in respect of such Transaction, as determined by Bank in

its sole discretion, but in no event later than the Hedge Period End Date.
	Hedge Period End Date:

	 	For each Transaction, as set forth in the related Supplemental Confirmation.
	Hedge Period Reference

Price:

	 	For each Transaction, as set forth in the related Trade Notification, to be

the average of the VWAP Prices for the Exchange Business Days in the Hedge

Period, subject to “Valuation Disruption” below.
	VWAP Price:

	 	For any Exchange Business Day, as determined by the Calculation Agent based

on the NASDAQ 10b-18 Volume Weighted Average Price per Share for the

regular trading session (including any extensions thereof) of the Exchange

on such Exchange Business Day (without regard to pre-open or after hours

trading outside of such regular trading session for such Exchange Business

Day), as published by Bloomberg at 4:15 p.m. New York time (or 15 minutes

following the end of any extension of the regular trading session) on such

Exchange Business Day, on Bloomberg page “GILD.Q <Equity> AQR_SEC”

(or any successor thereto), or if such price is not so reported on such

Exchange Business Day for any reason or is, in the Calculation Agent’s

reasonable discretion, erroneous, such VWAP Price shall be as reasonably

determined by the Calculation Agent in consultation with the Counterparty.

For purposes of calculating the VWAP Price, the Calculation Agent will

include only those trades that are reported during the period of time

during which Counterparty could purchase its own shares under Rule

10b-18(b)(2) and are effected pursuant to the conditions of Rule

10b-18(b)(3), each under the Securities Exchange Act of 1934, as amended

(the “Exchange Act”) (such trades, “Rule 10b-18 eligible transactions”).
	Forward Price:

	 	The average of the VWAP Prices for the Exchange Business Days in the

Calculation Period, subject to “Valuation Disruption” below.
	Forward Price

Adjustment Amount:

	 	

For each Transaction, as set forth in the related Supplemental Confirmation.
	Calculation Period:

	 	The period from and including the Calculation Period Start Date to and

including the Termination Date.
	Calculation Period

Start Date:

	 	For each Transaction, as set forth in the related Trade Notification, to be

the first Exchange Business Day immediately following the Hedge Completion

Date.
	Termination Date:

	 	The Scheduled Termination Date; provided that Bank shall have the right to

designate any Exchange Business Day on or after the First Acceleration Date

to be the Termination Date by delivering telephonic notice to Counterparty,

to be confirmed in writing, of any such designation no later than 11:59

p.m. New York City time on the Termination Date.
	Scheduled Termination

Date:

	 	For each Transaction, as set forth in the related Supplemental

Confirmation, subject to postponement as provided in “Valuation Disruption”

below.
	First Acceleration Date:

	 	For each Transaction, as set forth in the related Supplemental Confirmation.
	Valuation Disruption:

	 	The definition of “Market Disruption Event” in Section 6.3(a) of the Equity

Definitions is hereby amended by deleting the words “at any time during the

one-hour period that ends at the relevant Valuation Time, Latest Exercise

Time, Knock-in Valuation Time or Knock-out Valuation Time, as the case may

be” and inserting the words “at any time on any Scheduled Trading Day

during the Hedge Period, Calculation Period or Settlement Valuation Period”

after the word “material,” in the third line thereof.

Notwithstanding anything to the contrary in the Equity Definitions, to the

extent that a Disrupted Day occurs (i) in the Hedge Period or the

Calculation Period, the Calculation Agent may, in its good faith and

commercially reasonable discretion, postpone either or both of the Hedge

Period End Date and/or the Scheduled Termination Date, or (ii) in the

Settlement Valuation Period, the Calculation Agent may extend the

Settlement Valuation Period. If any such Disrupted Day is a Disrupted Day

because of a Market Disruption Event (or a deemed Market Disruption Event

as provided herein), the Calculation Agent shall determine whether (i) such

Disrupted Day is a Disrupted Day in full, in which case the VWAP Price for

such Disrupted Day shall not be included for purposes of determining the

Hedge Period Reference Price, the Forward Price or the Settlement Price, as

the case may be, or (ii) such Disrupted Day is a Disrupted Day only in

part, in which case the VWAP Price for such Disrupted Day shall be

determined by the Calculation Agent based on Rule 10b-18 eligible

transactions in the Shares on such Disrupted Day effected before the

relevant Market Disruption Event occurred and/or after the relevant Market

Disruption Event ended, and the weighting of the VWAP Price for the

relevant Exchange Business Days during the Hedge Period, the Calculation

Period or the Settlement Valuation Period, as the case may be, shall be

adjusted in a commercially reasonable manner by the Calculation Agent for

purposes of determining the Hedge Period Reference Price, the Forward Price

or the Settlement Price, as the case may be, with such adjustments based

on, among other factors, the duration of any Market Disruption Event and

the volume, historical trading patterns and price of the Shares.

If a Disrupted Day occurs during the Hedge Period, the Calculation Period

or the Settlement Valuation Period, as the case may be, and each of the

nine immediately following Scheduled Trading Days is a Disrupted Day, then

the Calculation Agent, in its good faith and commercially reasonable

discretion, shall deem such ninth Scheduled Trading Day to be an Exchange

Business Day that is not a Disrupted Day and determine the VWAP Price for

such ninth Scheduled Trading Day using its commercially reasonable estimate

of the value of the Shares on such ninth Scheduled Trading Day based on the

volume, historical trading patterns and price of the Shares and such other

factors as it deems appropriate.

Settlement Terms:

	 	 	 
	Physical Settlement:

	 	Applicable to Bank; provided that Bank does not, and shall not, make the

agreement or the representations set forth in Section 9.11 of the Equity

Definitions related to the restrictions imposed by applicable securities

laws with respect to any Shares delivered by Bank to Counterparty under any

Transaction. The Counterparty Settlement Provisions are set forth in Annex

A hereto.
	Number of Shares

to be Delivered:

	 	A number of Shares equal to (a) the Prepayment Amount divided by (b)(i) the

Forward Price minus (ii) the Forward Price Adjustment Amount; provided that

the Number of Shares to be Delivered shall not be less than the Minimum

Shares and not greater than the Maximum Shares. The Number of Shares to be

Delivered on the Settlement Date shall be reduced, but not below zero, by

any Shares delivered pursuant to the Initial Share Delivery and the Minimum

Share Delivery described below.
	Excess Dividend Amount:

	 	For the avoidance of doubt, all references to the Excess Dividend Amount

shall be deleted from Section 9.2(a)(iii) of the Equity Definitions.
	Settlement Date:

	 	The date that is one Settlement Cycle immediately following the Termination

Date.
	Settlement Currency:

	 	USD
	Initial Share Delivery:

	 	Bank shall deliver a number of Shares equal to the Initial Shares to

Counterparty on the Initial Share Delivery Date in accordance with Section

9.4 of the Equity Definitions, with the Initial Share Delivery Date deemed

to be a “Settlement Date” for purposes of such Section 9.4.
	Initial Share Delivery Date:

	 	For each Transaction, as set forth in the related Supplemental Confirmation.
	Initial Shares:

	 	For each Transaction, as set forth in the related Supplemental Confirmation.
	Minimum Share Delivery:

	 	Bank shall deliver a number of Shares equal to the excess, if any, of the

Minimum Shares over the Initial Shares on the Minimum Share Delivery Date

in accordance with Section 9.4 of the Equity Definitions, with the Minimum

Share Delivery Date deemed to be a “Settlement Date” for purposes of such

Section 9.4.
	Minimum Share Delivery

Date:

	 	The date one Settlement Cycle immediately following the Hedge Completion

Date.
	Minimum Shares:

	 	For each Transaction, as set forth in the related Supplemental Confirmation.
	Maximum Shares:

	 	For each Transaction, as set forth in the related Supplemental Confirmation.

Share Adjustments:

	 	 	 
	Potential Adjustment Event:

	 	Notwithstanding anything to the contrary

in Section 11.2(e) of the Equity

Definitions, an Extraordinary Dividend

shall not constitute a Potential

Adjustment Event.

It shall constitute an additional

Potential Adjustment Event if the

Scheduled Termination Date for any

Transaction is postponed pursuant to

“Valuation Disruption” above, in which

case the Calculation Agent may, in its

commercially reasonable discretion,

adjust any relevant terms of any such

Transaction as necessary to preserve as

nearly as practicable the fair value of

such Transaction to Bank prior to such

postponement.
	Extraordinary Dividend:

	 	Any dividend or distribution on the

Shares (other than any dividend or

distribution of the type described in

Section 11.2(e)(i) or Section

11.2(e)(ii)(A) or (B) of the Equity

Definitions) that has an ex-dividend

date occurring during the Relevant

Dividend Period (as defined below). For

the avoidance of doubt, the Calculation

Agent shall not make any adjustments to

account for changes in extraordinary

dividends under any circumstances under

this Master Confirmation.
	Method of Adjustment:

	 	Calculation Agent Adjustment

Extraordinary Events:

	 	 	 
	Consequences of

Merger Events:

	 	

	(a)   Share-for-Share:

	 	Modified Calculation Agent Adjustment
	(b)   Share-for-Other:

	 	Cancellation and Payment
	(c)   Share-for-Combined:

	 	Component Adjustment
	Tender Offer:

	 	Applicable; provided that (i) Section

12.1(l) of the Equity Definitions shall be

amended (x) by deleting the parenthetical

in the fifth line thereof, (y) by replacing

“that” in the fifth line thereof with

“whether or not such announcement” and (z)

by adding immediately after the words

“Tender Offer” in the fifth line thereof “,

and any publicly announced change or

amendment to such an announcement

(including the announcement of an

abandonment of such intention)” and (ii)

Sections 12.3(a) and 12.3(d) of the Equity

Definitions shall each be amended by

replacing each occurrence of the words

“Tender Offer Date” by “Announcement Date.”
	Consequences of

Tender Offers:

	 	

	(a)   Share-for-Share:

	 	Modified Calculation Agent Adjustment
	(b)   Share-for-Other:

	 	Modified Calculation Agent Adjustment
	(c)   Share-for-Combined:

	 	Modified Calculation Agent Adjustment
	Nationalization,

Insolvency or Delisting:

	 	Cancellation and Payment; provided that in

addition to the provisions of Section

12.6(a)(iii) of the Equity Definitions, it

shall also constitute a Delisting if the

Exchange is located in the United States

and the Shares are not immediately

re-listed, re-traded or re-quoted on any of

the New York Stock Exchange, the American

Stock Exchange, The NASDAQ Global Select

Market or The NASDAQ Global Market (or

their respective successors); if the Shares

are immediately re-listed, re-traded or

re-quoted on any such exchange or quotation

system, such exchange or quotation system

shall be deemed to be the Exchange.

Additional Disruption Events:

	 	 	 
	Change in Law:

	 	Applicable; provided that Section

12.9(a)(ii) of the Equity Definitions

shall be amended by deleting clause (Y)

in its entirety.
	Insolvency Filing:

	 	Applicable

	 	 	Additional Termination Event(s):      Notwithstanding anything to the contrary in the Equity
Definitions, if, as a result of an Extraordinary Event, any Transaction would be cancelled or
terminated (whether in whole or in part) pursuant to Article 12 of the Equity Definitions, an
Additional Termination Event (with such terminated Transaction(s) (or portions thereof) being
the Affected Transaction(s) and Counterparty being the sole Affected Party (provided that, (i)
in the case of a Failure to Deliver, Bank shall be the sole Affected Party and (ii) in the
case of Change in Law, both parties shall be Affected Parties)) shall be deemed to occur, and,
in lieu of Sections 12.7, 12.8 and 12.9 of the Equity Definitions, Section 6 of the Agreement
shall apply to such Affected Transaction(s).

The declaration by the Issuer of any Extraordinary Dividend
will constitute an Additional Termination Event, with Counterparty
as the sole Affected Party and all Transactions hereunder as the
Affected Transactions.

	 	 	Relevant Dividend Period:                 The period from and including the first day of the Hedge
Period to and including the later of the last day of the Relevant Period (as defined in
Section 4(f) of this Master Confirmation) and the last day of the Settlement Valuation Period,
if any.

Non-Reliance/Agreements and

Acknowledgements Regarding

Hedging Activities/Additional

Acknowledgements:                      Applicable

	 	 	Transfer:                                          Notwithstanding anything to the contrary in the
Agreement, Bank may assign, transfer and set over all rights, title and interest, powers,
privileges and remedies of Bank under any Transaction, in whole or in part, to an affiliate of
Bank (the “Assignee”) without the consent of Counterparty; provided that (i) Counterparty will
not, as a result of such transfer, be required to pay to the Assignee an amount in respect of
an Indemnifiable Tax under Section 2(d)(i)(4) of the Agreement, (ii) the Assignee will not, as
a result of such transfer, be required to withhold or deduct any amount on account of a Tax
under Section 2(d)(i) of the Agreement, unless the Assignee would be required to make
additional payments pursuant to Section 2(d)(i)(4) of the Agreement corresponding to such
excess, in which case, Counterparty shall have the right to elect that Bank deliver Shares in
lieu of making any such additional payments in cash as if the amount required to be so paid
were a Payment Amount in accordance with Section 14 of this Master Confirmation, (iii) no
Event of Default, Potential Event of Default or Termination Event with respect to the Assignee
shall exist after giving effect to such assignment, transfer or set over, (iv) at the time of
the Transfer, the transferred Transaction represents a legal, valid and binding obligation of
the Assignee and (v) immediately after such transfer, the Counterparty shall receive notice
thereof.

	 	 	Bank Payment Instructions:            To be provided by Bank

	 	 	Counterparty’s Contact Details

for Purpose of Giving Notice:         Kevin Olson

Corporate Treasurer

Gilead Sciences, Inc.

333 Lakeside Drive

Foster City, CA 94404

Ph: 650-522-6217

Fax: 650-522-5497

Email: Kevin.Olson@Gilead.com

with a copy to:

Santosh Ghirnikar

Director, Treasury

Gilead Sciences, Inc.

333 Lakeside Drive

Foster City, CA 94404

Ph: 650-522-1833

Fax: 650-522-5497

Email: santosh.ghirnikar@gilead.com

	 	 	Bank’s Contact Details for

	 	 	 	Purpose of Giving Notice: Citibank, N.A.

390 Greenwich Street

New York, NY 10013

Attention: Equity Derivatives

Facsimile: 212-723-8744

Telephone: 212-723-7362

	2.	 	Calculation Agent.             Bank, unless otherwise specified in a Confirmation
relating to a Transaction. If Bank is the sole Defaulting Party with respect to an Event of
Default or a sole Affected Party with respect to a Termination Event, Counterparty may appoint
a reference market-maker unaffiliated with Counterparty to act as the Calculation Agent. Bank
shall bear all costs and expenses of appointing a third party Calculation Agent.

3. Additional Mutual Representations, Warranties and Covenants of Each Party. In addition
to the representations, warranties and covenants in the Agreement, each party represents, warrants
and covenants to the other party that:

(a) Eligible Contract Participant. It is an “eligible contract participant”, as
defined in the U.S. Commodity Exchange Act (as amended), and is entering into each Transaction
hereunder as principal (and not as agent or in any other capacity, fiduciary or otherwise) and not
for the benefit of any third party.

(b) Accredited Investor. Each party acknowledges that the offer and sale of each
Transaction to it is intended to be exempt from registration under the Securities Act of 1933, as
amended (the “Securities Act”), by virtue of Section 4(2) thereof. Accordingly, each party
represents and warrants to the other that (i) it has the financial ability to bear the economic
risk of its investment in each Transaction and is able to bear a total loss of its investment, (ii)
it is an “accredited investor” as that term is defined under Regulation D under the Securities Act
and (iii) the disposition of each Transaction is restricted under this Master Confirmation, the
Securities Act and state securities laws.

4. Additional Representations, Warranties and Covenants of Counterparty. In addition to
the representations, warranties and covenants in the Agreement, Counterparty represents, warrants
and covenants to Bank that:

(a) It is not entering into any Transaction (i) on the basis of, and is, as of the Trade Date
for any Transaction, not aware of, any material non-public information with respect to the Shares
(ii) in anticipation of, in connection with, or to facilitate, a distribution of its securities, a
self tender offer or a third-party tender offer or (iii) to create actual or apparent trading
activity in the Shares (or any security convertible into or exchangeable for the Shares) or to
raise or depress or otherwise manipulate the price of the Shares (or any security convertible into
or exchangeable for the Shares).

(b) Each Transaction is being entered into pursuant to a publicly disclosed Share buy-back
program and its Board of Directors has approved the use of derivatives to effect the Share buy-back
program.

(c) It intends that each Transaction qualifies as an equity instrument for purposes of EITF
Issue No. 00-19 as in effect on the Trade Date. Notwithstanding the foregoing and without limiting
the generality of Section 13.1 of the Equity Definitions, it acknowledges that neither Bank nor any
of its affiliates is making any representations or warranties or taking any position or expressing
any view with respect to the treatment of any Transaction under any accounting standards including
FASB Statements 128, 133 as amended, or 149, 150, EITF 00-19, 01-6 or EITF 03-6 (or any successor
issue statements) or under the Financial Accounting Standards Board’s Liabilities & Equity Project.

(d) As of (i) the date hereof and (ii) the Trade Date for each Transaction hereunder,
Counterparty is in compliance with its reporting obligations under the Exchange Act and its most
recent Annual Report on Form 10-K, together with all reports subsequently filed by it pursuant to
the Exchange Act, taken together and as amended and supplemented to the date of this
representation, do not, as of their respective filing dates, contain any untrue statement of a
material fact or omit to state any material fact required to be stated therein or necessary to make
the statements therein, in the light of the circumstances under which they were made, not
misleading;

(e) Counterparty is aware of its reporting obligations as required under Regulation S-K under
the Exchange Act in respect of the Transactions hereunder.

(f) The Shares are not, and Counterparty will not cause the Shares to be, subject to a
“restricted period” (as defined in Regulation M promulgated under the Exchange Act) at any time
during any Regulation M Period (as defined below) for any Transaction unless Counterparty has
provided written notice to Bank of such restricted period not later than the Scheduled Trading Day
immediately preceding the first day of such “restricted period”. Counterparty acknowledges that
any such notice may cause a Disrupted Day to occur pursuant to Section 5 below. Accordingly,
Counterparty acknowledges that its delivery of such notice must comply with the standards set forth
in Section 6(c) below. “Regulation M Period” means, for any Transaction, (i) the Relevant Period
(as defined below) and (ii) the Settlement Valuation Period, if any, for such Transaction.
“Relevant Period” means, for any Transaction, the period commencing on the first day of the Hedge
Period for such Transaction and ending on the earlier of (i) the Scheduled Termination Date and
(ii) the last Additional Relevant Day (as specified in the related Supplemental Confirmation) for
such Transaction, or such earlier day as elected by Bank and communicated to Counterparty on such
day (or, if later, the First Acceleration Date without regard to any acceleration thereof pursuant
to “Special Provisions for Friendly Transaction Announcements” below).

(g) As of the Trade Date for each Transaction, Counterparty is not “insolvent” (as such term
is defined under Section 101(32) of the U.S. Bankruptcy Code (Title 11 of the United States Code)
(the “Bankruptcy Code”)) and Counterparty would be able to purchase a number of Shares with a value
equal to the Prepayment Amount in compliance with the laws of the jurisdiction of Counterparty’s
incorporation.

(h) Counterparty is not and, after giving effect to any Transaction, will not be, required to
register as an “investment company” as such term is defined in the Investment Company Act of 1940,
as amended.

(i) Counterparty will not, during any Relevant Period or, if applicable, any Settlement
Valuation Period, enter into agreements similar to the Transactions described herein where any
initial hedge period, calculation period, relevant period or settlement valuation period (each
however defined) in such other transaction will overlap at any time (including as a result of
extensions in such initial hedge period, calculation period, relevant period or settlement
valuation period as provided in the relevant agreements) with any Relevant Period or, if
applicable, any Settlement Valuation Period under this Master Confirmation. In the event that the
initial hedge period, relevant period, calculation period or settlement valuation period in any
other similar transaction overlaps with any Relevant Period or, if applicable, Settlement Valuation
Period under this Master Confirmation as a result of any postponement of the Termination Date or
extension of the Settlement Valuation Period pursuant to “Valuation Disruption” above, Counterparty
shall promptly amend such transaction to avoid any such overlap.

5. Regulatory Disruption. In the event that Bank concludes, in good faith and in its
commercially reasonable discretion, that it is appropriate with respect to any legal, regulatory or
self-regulatory requirements or related policies and procedures, for it to refrain from purchasing
Shares on any Scheduled Trading Day or Days during the Hedge Period, the Calculation Period or, if
applicable, the Settlement Valuation Period, Bank may by written notice to Counterparty elect to
deem that a Market Disruption Event has occurred and will be continuing on such Scheduled Trading
Day or Days.

6. 10b5-1 Plan.

(a)          Counterparty is entering into this Master Confirmation and each
Transaction hereunder in good faith and not as part of a plan or scheme to evade the prohibitions
of Rule 10b5-1 under the Exchange Act (“Rule 10b5-1”) or any other antifraud or anti-manipulation
provisions of the federal or applicable state securities laws and that it has not entered into or
altered and will not enter into or alter any corresponding or hedging transaction or position with
respect to the Shares. It is the intent of the parties that each Transaction entered into under
this Master Confirmation comply with the requirements of paragraphs (c)(1)(i)(A) and (B) of Rule
10b5-1 and each Transaction entered into under this Master Confirmation shall be interpreted to
comply with the requirements of Rule 10b5-1(c).

(b)          Counterparty will not seek to control or influence Bank’s decision to
make any “purchases or sales” (within the meaning of Rule 10b5-1(c)(1)(i)(B)(3)) under any
Transaction entered into under this Master Confirmation, including, without limitation, Bank’s
decision to enter into any hedging transactions. Counterparty represents and warrants that it has
consulted with its own advisors as to the legal aspects of its adoption and implementation of this
Master Confirmation, each Supplemental Confirmation and each Trade Notification under Rule 10b5-1.

(c)          Counterparty acknowledges and agrees that any amendment, modification, waiver or
termination of this Master Confirmation, the relevant Supplemental Confirmation or Trade
Notification must be effected in accordance with the requirements for the amendment or termination
of a “plan” as defined in Rule 10b5-1(c). Without limiting the generality of the foregoing, any
such amendment, modification, waiver or termination shall be made in good faith and not as part of
a plan or scheme to evade the prohibitions of Rule 10b-5, and no such amendment, modification or
waiver shall be made at any time at which Counterparty or any officer, director, manager or similar
person of Counterparty is aware of any material non-public information regarding Counterparty or
the Shares.

7. Rule 10b-18. (a)  Counterparty (or any “affiliated purchaser” as defined in Rule 10b-18
under the Exchange Act (“Rule 10b-18”)) shall not, without the prior written consent of Bank,
directly or indirectly purchase any Shares (including by means of a derivative instrument), listed
contracts on the Shares or securities that are convertible into, or exchangeable or exercisable for
Shares (including, without limitation, any Rule 10b-18 purchases of blocks (as defined in Rule
10b-18)) during any Relevant Period or, if applicable, Settlement Valuation Period, except through
Bank; provided that purchases effected by or for an issuer plan of Counterparty by an agent
independent of the issuer within the meaning of Rule 10b-18(a)(13)(ii) shall not be subject to this
Section 7(a).

(b)          With respect to all purchases of Shares made by Bank during the Hedge Period of
any Transaction, Bank will make purchases in a manner so that, if such purchases were made by
Counterparty or an “affiliated purchaser” (as such term is defined under Rule 10b-18) of
Counterparty, they would meet the requirements of Rule 10b-18(b)(2), (3) and (4) under the Exchange
Act, and effect calculations in respect thereof, taking into account any applicable Securities and
Exchange Commission or staff no-action letters or interpretations as appropriate.

8. Special Provisions for Merger Transactions. Notwithstanding anything to the contrary
herein or in the Equity Definitions:

(a)           Counterparty agrees that it:

(i)       will not during the period commencing on the Trade Date through the end of
the Relevant Period or, if applicable, the Settlement Valuation Period for any Transaction
make, or permit to be made, any public announcement (as defined in Rule 165(f) under the
Securities Act) of any Merger Transaction or potential Merger Transaction unless such public
announcement is made prior to the opening or after the close of the regular trading session
on the Exchange for the Shares;

(ii)      shall promptly (but in any event prior to the next opening of the regular
trading session on the Exchange) notify Bank following any such announcement that such
announcement has been made; and

(iii)     shall promptly (but in any event prior to the next opening of the regular
trading session on the Exchange) provide Bank with written notice specifying (i)
Counterparty’s average daily Rule 10b-18 Purchases (as defined in Rule 10b-18) during the
three full calendar months immediately preceding the announcement date that were not
effected through Bank or its affiliates and (ii) the number of Shares purchased pursuant to
the proviso in Rule 10b-18(b)(4) under the Exchange Act for the three full calendar months
preceding the announcement date. Such written notice shall be deemed to be a certification
by Counterparty to Bank that such information is true and correct. In addition,
Counterparty shall promptly notify Bank of the earlier to occur of the completion of such
transaction and the completion of the vote by target shareholders. Counterparty
acknowledges that any such notice may cause the terms of any Transaction to be adjusted or
such Transaction to be terminated; accordingly, Counterparty acknowledges that its delivery
of such notice must comply with the standards set forth in Section 6(c) above.

(b)           In connection with a Merger Transaction, Bank in good faith and its commercially
reasonable discretion may (i) suspend the Hedge Period, the Calculation Period and/or any
Settlement Valuation Period and postpone the Scheduled Termination Date of any Transaction and make
related adjustments as if such event were a Potential Adjustment Event or (ii) treat the occurrence
of such public announcement as an Additional Termination Event with both parties as Affected
Parties and the Transactions hereunder as the Affected Transactions and, for the avoidance of
doubt, with the amount under Section 6(e) of the Agreement determined in a commercially reasonable
manner taking into account the fact that the Calculation Period or Settlement Valuation Period, as
the case may be, had fewer Scheduled Trading Days than originally anticipated.

“Merger Transaction” means any merger, acquisition or similar transaction involving a
recapitalization as contemplated by Rule 10b-18(a)(13)(iv) under the Exchange Act. For the
avoidance of doubt, transactions in which the consideration is solely cash and there is no
valuation period shall not constitute “Merger Transactions” hereunder.

9. Special Provisions for Friendly Transaction Announcements. (a) If a Friendly
Transaction Announcement occurs on or prior to the Settlement Date for any Transaction, then the
Number of Shares to be Delivered for such Transaction shall be determined as if the words “less
than the Minimum Shares and not” and “, but not below zero,” were deleted from the definition
thereof. If a Friendly Transaction Announcement occurs after the Trade Date, but prior to the
First Acceleration Date of any Transaction, the First Acceleration Date shall be the date of such
Friendly Transaction Announcement. If a Friendly Transaction Announcement occurs after the
Settlement Date for any Transaction or any earlier date of termination or cancellation of such
Transaction pursuant to Section 6 of the Agreement or Article 12 of the Equity Definitions, then a
second settlement of such Transaction (a “Second Settlement”) shall occur (notwithstanding such
earlier termination or cancellation) with a Number of Shares to be Delivered equal to the lesser of
(i) zero and (ii) (x) the Number of Shares to be Delivered determined pursuant to the first
sentence of this paragraph as if such Friendly Transaction Announcement occurred prior to such
Settlement Date minus (y) the Number of Shares to be Delivered determined pursuant to Section 1 of
this Master Confirmation (provided that in the case of a Second Settlement occurring after such an
early termination or cancellation, a Number of Shares to be Delivered shall not be determined and
instead a Forward Cash Settlement Amount will be determined as provided in Annex A). If the Number
of Shares to be Delivered for any settlement of any Transaction is a negative number, then the
terms of the Counterparty Settlement Provisions in Annex A shall apply.

(b)          “Friendly Transaction Announcement” means (i) an Acquisition Transaction
Announcement by Counterparty or its board of directors prior to the last day of the Relevant Period
or any earlier date of termination or cancellation of the relevant Transaction pursuant to Section
6 of the Agreement or Article 12 of the Equity Definitions (such date, the “Actual Termination
Date”), (ii) an announcement by Counterparty or its board of directors prior to the date three
months following the Scheduled Termination Date that an Acquisition Transaction that is the subject
of an Acquisition Transaction Announcement occurring prior to the Actual Termination Date has been
approved, agreed to, recommended by or otherwise consented to by Counterparty or its board of
directors, or negotiated by Counterparty or any authorized representative of Counterparty, or (iii)
where Counterparty or its board of directors has a legal obligation to make a recommendation to its
shareholders in respect of any such Acquisition Transaction contemplated by clause (i) or (ii) of
this Section 9(b) prior to the date three months following the Scheduled Termination Date, the
absence of a recommendation that its shareholders reject such transaction.

(c)          “Acquisition Transaction Announcement” means (i) the announcement of an
Acquisition Transaction, (ii) an announcement that Counterparty or any of its subsidiaries has
entered into an agreement, a letter of intent or an understanding designed to result in an
Acquisition Transaction, (iii) the announcement of the intention to solicit or enter into, or to
explore strategic alternatives or other similar undertaking that may include, an Acquisition
Transaction, or (iv) any other announcement that in the reasonable judgment of the Calculation
Agent may result in an Acquisition Transaction. For the avoidance of doubt, announcements as used
in the definition of Acquisition Transaction Announcement refer to any public announcement whether
made by the Issuer or a third party.

(d)          “Acquisition Transaction” means (i) any Merger Event (for purposes of this
definition the definition of Merger Event shall be read with the references therein to “100%” being
replaced by “25%” and to “50%” by “75%” and without reference to the clause beginning immediately
following the definition of Reverse Merger therein to the end of such definition) or Tender Offer
or any other transaction involving the merger of Counterparty with or into any third party, (ii)
the sale or transfer of all or substantially all of the assets of Counterparty, (iii) a
recapitalization, reclassification, binding share exchange or other similar transaction and (iv)
any transaction in which Counterparty or its board of directors has a legal obligation to make a
recommendation to its shareholders in respect of such transaction (whether pursuant to Rule 14e-2
under the Exchange Act or otherwise).

	10.	 	Acknowledgments. (a) The parties hereto intend for:

(i)         each Transaction to be a “securities contract” as defined in Section 741(7)
of the Bankruptcy Code, a “swap agreement” as defined in Section 101(53B) of the Bankruptcy
Code and a “forward contract” as defined in Section 101(25) of the Bankruptcy Code, and the
parties hereto to be entitled to the protections afforded by, among other Sections, Sections
362(b)(6), 362(b)(17), 362(b)(27), 362(o), 546(e), 546(g), 546(j), 555, 556, 560 and 561 of
the Bankruptcy Code;

(ii)         the Agreement to be a “master netting agreement” as defined in Section
101(38A) of the Bankruptcy Code;

(iii)        a party’s right to liquidate, terminate or accelerate any Transaction, net
out or offset termination values or payment amounts, and to exercise any other remedies upon
the occurrence of any Event of Default or Termination Event under the Agreement with respect
to the other party or any Extraordinary Event that results in the termination or
cancellation of any Transaction to constitute a “contractual right” (as defined in the
Bankruptcy Code); and

(iv)        all payments for, under or in connection with each Transaction, all
payments for the Shares (including, for the avoidance of doubt, payment of the Prepayment
Amount) and the transfer of such Shares to constitute “settlement payments” and “transfers”
(as defined in the Bankruptcy Code).

(b)           Counterparty acknowledges that:

(i)       during the term of any Transaction, Bank and its affiliates may buy or
sell Shares or other securities or buy or sell options or futures contracts or enter into swaps or
other derivative securities in order to establish or adjust its Hedge Position with respect to such
Transaction;

(ii)        Bank and its affiliates may also be active in the market for the Shares
other than in connection with hedging activities in relation to any Transaction;

(iii)     Bank shall make its own determination as to whether, when or in what
manner any hedging or market activities in Counterparty’s securities shall be conducted and shall
do so in a manner that it deems appropriate to hedge its price and market risk with respect to the
Forward Price and the VWAP Price;

(iv)     any market activities of Bank and its affiliates with respect to the Shares
may affect the market price and volatility of the Shares, as well as the Forward Price and VWAP
Price, each in a manner that may be adverse to Counterparty; and

(v)      each Transaction is a derivatives transaction in which it has granted Bank
an option; Bank may purchase shares for its own account at an average price that may be greater
than, or less than, the price paid by Counterparty under the terms of the related Transaction.

(c)          Counterparty and Bank acknowledge that none of Counterparty, Bank, or
any of their respective affiliates, intends to treat the payment of the Prepayment Amount by
Counterparty to Bank on the Prepayment Date with respect to any Transaction as a loan for purposes
of filing any U.S. federal, state or local tax return.

(d)          Bank hereby represents and warrants to Counterparty that, for U.S.
federal income tax purposes: (i) it is a beneficial owner of each payment received or to be
received under this Confirmation; and (ii) each such payment received under this Confirmation will
be effectively connected with its conduct of a trade or business in the United States. Any
successor entity to Bank shall make such representations and provide such documents as are
necessary to ensure that any payments made pursuant to this transaction are free of U.S.
withholding tax.

11. Credit Support Documents. For each Transaction, as set forth in the related
Supplemental Confirmation.

12. Set-off. (a) The parties agree to amend Section 6 of the Agreement by adding a
new Section 6(f) thereto as follows:

“(f) Upon the occurrence of an Event of Default or Termination
Event with respect to a party who is the Defaulting Party or the
Affected Party (“X”), the other party (“Y”) will have the right
(but not be obliged) without prior notice to X or any other person
to set-off or apply any obligation of X owed to Y (or any Affiliate
of Y) (whether or not matured or contingent and whether or not
arising under the Agreement, and regardless of the currency, place
of payment or booking office of the obligation) against any
obligation of Y (or any Affiliate of Y) owed to X (whether or not
matured or contingent and whether or not arising under the
Agreement, and regardless of the currency, place of payment or
booking office of the obligation). Y will give notice to the other
party of any set-off effected under this Section 6(f).

Amounts (or the relevant portion of such amounts) subject to
set-off may be converted by Y into the Termination Currency at the
rate of exchange at which such party would be able, acting in a
reasonable manner and in good faith, to purchase the relevant
amount of such currency. If any obligation is unascertained, Y may
in good faith estimate that obligation and set-off in respect of
the estimate, subject to the relevant party accounting to the other
when the obligation is ascertained. Nothing in this Section 6(f)
shall be effective to create a charge or other security interest.
This Section 6(f) shall be without prejudice and in addition to any
right of set-off, combination of accounts, lien or other right to
which any party is at any time otherwise entitled (whether by
operation of law, contract or otherwise).”

(b)          Notwithstanding anything to the contrary in the foregoing, Bank agrees not to set
off or net amounts due from Counterparty with respect to any Transaction against amounts due from
Bank to Counterparty with respect to contracts or instruments that are not Equity Contracts.
“Equity Contract” means any transaction or instrument that does not convey to Bank rights, or the
ability to assert claims, that are senior to the rights and claims of common stockholders in the
event of Counterparty’s bankruptcy.

13. Delivery of Shares. Notwithstanding anything to the contrary herein, Bank may, by
prior notice to Counterparty, satisfy its obligation to deliver any Shares or other securities on
any date due (an “Original Delivery Date”) by making separate deliveries of Shares or such
securities, as the case may be, at more than one time on or prior to such Original Delivery Date,
so long as the aggregate number of Shares and other securities so delivered on or prior to such
Original Delivery Date is equal to the number required to be delivered on such Original Delivery
Date.

14. Early Termination. In the event that an Early Termination Date (whether as a result of
an Event of Default or a Termination Event) occurs or is designated with respect to any Transaction
(except as a result of a Merger Event in which the consideration or proceeds to be paid to holders
of Shares consists solely of cash), if either party would owe any amount to the other party
pursuant to Section 6(d)(ii) and 6(e) of the Agreement (any such amount, a “Payment Amount”), then,
in lieu of any payment of such Payment Amount, Counterparty may, no later than the Early
Termination Date or the date on which such Transaction is terminated, elect to deliver or for Bank
to deliver, as the case may be, to the other party a number of Shares (or, in the case of a Merger
Event, a number of units, each comprising the number or amount of the securities or property that a
hypothetical holder of one Share would receive in such Merger Event (each such unit, an
“Alternative Delivery Unit” and, the securities or property comprising such unit, “Alternative
Delivery Property”)) with a value equal to the Payment Amount, as determined by the Calculation
Agent (and the parties agree that, in making such determination of value, the Calculation Agent may
take into account a number of factors, including the market price of the Shares or Alternative
Delivery Property on the date of early termination and, if such delivery is made by Bank, the
prices at which Bank purchases Shares or Alternative Delivery Property to fulfill its delivery
obligations under this Section 14); provided that in determining the composition of any Alternative
Delivery Unit, if the relevant Merger Event involves a choice of consideration to be received by
holders, such holder shall be deemed to have elected to receive the maximum possible amount of
cash. If such delivery is made by Counterparty, paragraphs 2 through 7 of Annex A shall apply as if
such delivery were a settlement of the Transaction to which Net Share Settlement applied, the Cash
Settlement Payment Date were the Early Termination Date and the Forward Cash Settlement Amount were
zero (0) minus the Payment Amount owed by Counterparty. In no event, however, shall the number of
Shares required to be delivered by Counterparty pursuant to this Master Confirmation be greater
than the Reserved Shares (as defined in the Annex A).

15. Payment Date upon Early Termination. Notwithstanding anything to the contrary in
Section 6(d)(ii) of the Agreement, all amounts calculated as being due in respect of an Early
Termination Date under Section 6(e) of the Agreement will be payable on the day that notice of the
amount payable is effective; provided that if Counterparty elects to receive Shares or Alternative
Delivery Property in accordance with Section 14, such Shares or Alternative Delivery Property shall
be delivered on a date selected by Bank as promptly as practicable in a commercially reasonable
manner.

16. Special Provisions for Counterparty Payments. The parties hereby agree that,
notwithstanding anything to the contrary herein or in the Agreement, in the event that an Early
Termination Date (whether as a result of an Event of Default or a Termination Event) occurs or is
designated with respect to any Transaction and, as a result, Counterparty owes to Bank an amount
calculated under Section 6(e) of the Agreement, such amount shall be deemed to be zero; provided
that following a Friendly Transaction Announcement, this Section 16 shall cease to apply.

17. Delivery of Cash. For the avoidance of doubt, nothing in this Master Confirmation
shall be interpreted as requiring Counterparty to deliver cash in respect of the settlement of the
Transactions contemplated by this Master Confirmation following payment by Counterparty of the
relevant Prepayment Amount, except in circumstances where the required cash settlement thereof is
permitted for classification of the contract as equity by EITF 00-19 as in effect on the relevant
Trade Date (including, without limitation, where Counterparty so elects to deliver cash or fails
timely to elect to deliver Shares or Alternative Delivery Property in respect of the settlement of
such Transactions).

18. Agreements in Respect of Termination Amounts. Notwithstanding any provision of this
Master Confirmation, any Supplemental Confirmation, the Agreement or the Equity Definitions to the
contrary, in determining any amounts payable in respect of the termination or cancellation of any
Transaction pursuant to Section 6 of the Agreement, Article 12 of the Equity Definitions or Section
14 of this Master Confirmation, the Calculation Agent shall make such determination without regard
to changes in dividends (including, without limitation, Extraordinary Dividends) stock loan rates,
liquidity or hedging costs.

19. Agreement in Respect of Adjustments. Notwithstanding any provision of this Master
Confirmation, any Supplemental Confirmation, the Agreement or the Equity Definitions to the
contrary, the Calculation Agent shall not make any adjustment in respect of any Transaction
pursuant to Article 11 or Article 12 of the Equity Definitions or pursuant to this Master
Confirmation to account for changes in dividends (including, without limitation, Extraordinary
Dividends), stock loan rate, liquidity or hedging costs.

20. Explanations Provided. As soon as reasonably practicable upon request after any
calculation, adjustment or determination with respect to any Transaction hereunder the Calculation
Agent (or Bank, as applicable, if making any calculation, adjustment or determination expressly
provided in this Master Confirmation to be made by Bank) shall provide to Counterparty a reasonably
detailed explanation of such calculation, adjustment or determination.

21. Claim in Bankruptcy. Bank acknowledges and agrees that this Confirmation is not
intended to convey to it rights with respect to the Transaction that are senior to the claims of
common stockholders in the event of Counterparty’s bankruptcy.

22. General Obligations Law of New York. With respect to each Transaction, (i) this Master
Confirmation, together with the related Supplemental Confirmation, as supplemented by the related
Trade Notification, is a “qualified financial contract”, as such term is defined in Section
5-701(b)(2) of the General Obligations Law of New York (the “General Obligations Law”); (ii) such
Trade Notification constitutes a “confirmation in writing sufficient to indicate that a contract
has been made between the parties” hereto, as set forth in Section 5-701(b)(3)(b) of the General
Obligations Law; and (iii) this Master Confirmation, together with the related Supplemental
Confirmation, constitutes a prior “written contract” as set forth in Section 5-701(b)(1)(b) of the
General Obligations Law, and each party hereto intends and agrees to be bound by this Master
Confirmation and the related Supplemental Confirmation, as supplemented by the Trade Notification.

23. Governing Law. The Agreement, this Master Confirmation, each Supplemental
Confirmation, each Trade Notification and all matters arising in connection with the Agreement,
this Master Confirmation, each Supplemental Confirmation and each Trade Notification shall be
governed by, and construed and enforced in accordance with, the laws of the State of New York
(without reference to its choice of laws doctrine other than Title 14 of Article 5 of the New York
General Obligations Law).

	24.	 	Offices.

(a)          The Office of Bank for each Transaction is: 390 Greenwich Street, New
York, NY 10013.

(b)          The Office of Counterparty for each Transaction is: 333 Lakeside Drive,
Foster City, California 94404.

25. Arbitration. The Agreement, this Master Confirmation, each Supplemental Confirmation
and each Trade Notification are subject to the following arbitration provisions:

(a)          All parties to this Confirmation are giving up the right to sue each
other in court, including the right to a trial by jury, except as provided by the rules of the
arbitration forum in which a claim is filed.

(b)          Arbitration awards are generally final and binding; a party’s ability to
have a court reverse or modify an arbitration award is very limited.

(c)          The ability of the parties to obtain documents, witness statements and
other discovery is generally more limited in arbitration than in court proceedings.

(d)          The arbitrators do not have to explain the reason(s) for their award.

(e)          The panel of arbitrators will typically include a minority of
arbitrators who were or are affiliated with the securities industry, unless Counterparty is a
member of the organization sponsoring the arbitration facility, in which case all arbitrators may
be affiliated with the securities industry.

(f)          The rules of some arbitration forums may impose time limits for bringing
a claim in arbitration. In some cases, a claim that is ineligible for arbitration may be brought
in court.

(g)          The rules of the arbitration forum in which the claim is filed, and any
amendments thereto, shall be incorporated into this Master Confirmation.

Counterparty agrees that any and all controversies that may arise between Counterparty and
Bank, including, but not limited to, those arising out of or relating to the Agreement or any
Transaction hereunder, shall be determined by arbitration conducted before The New York Stock
Exchange, Inc. (“NYSE”) or NASD Dispute Resolution (“NASD-DR”), or, if the NYSE and NASD-DR decline
to hear the matter, before the American Arbitration Association, in accordance with their
arbitration rules then in force. The award of the arbitrator shall be final, and judgment upon the
award rendered may be entered in any court, state or federal, having jurisdiction.

No person shall bring a putative or certified class action to arbitration, nor seek to enforce
any pre-dispute arbitration agreement against any person who has initiated in court a putative
class action or who is a member of a putative class who has not opted out of the class with respect
to any claims encompassed by the putative class action until: (i) the class certification is
denied; (ii) the class is decertified; or (iii) Counterparty is excluded from the class by the
court.

Such forbearance to enforce an agreement to arbitrate shall not constitute a waiver of any
rights under this Master Confirmation except to the extent stated herein.

26. Counterparts.         This Master Confirmation may be executed in any number
of counterparts, all of which shall constitute one and the same instrument, and any party hereto
may execute this Master Confirmation by signing and delivering one or more counterparts.

1

IN WITNESS WHEREOF, the parties hereto have caused this Master Confirmation to be duly
executed by their respective authorized officers as of the day and year first written above.

	 	 	 
	CITIBANK, N.A.
	By:

	 	/s/ Jason Shrednick
	
 
	 	 

	 	 	Name: Jason Shrednick

Title: Authorized Signatory

	 	 	 
	GILEAD SCIENCES, INC.
	By:

	 	/s/ Robin L. Washington
	
 
	 	 

	 	 	Name: Robin L. Washington

Title: Senior Vice Presidnet and Chief

Financial Officer

2

SCHEDULE A

SUPPLEMENTAL CONFIRMATION

	 	 	 
	To:

	 	Gilead Sciences, Inc.

333 Lakeside Drive

Foster City, CA 94404
	From:

	 	Citibank, N.A.
	Subject:

	 	Collared Accelerated Stock Buyback
	Date:

	 	[     ]

The purpose of this Supplemental Confirmation is to confirm the terms and conditions of the
Transaction entered into between Citibank, N.A. (“Bank”) and Gilead Sciences, Inc. (“Counterparty”)
(together, the “Contracting Parties”) on the Trade Date specified below. This Supplemental
Confirmation is a binding contract between Bank and Counterparty as of the relevant Trade Date for
the Transaction referenced below.

1.          This Supplemental Confirmation supplements, forms part of, and is subject to the Master
Confirmation dated as of October 21, 2008 (the “Master Confirmation”) between the Contracting
Parties, as amended and supplemented from time to time. All provisions contained in the Master
Confirmation govern this Supplemental Confirmation except as expressly modified below.

2.          The terms of the Transaction to which this Supplemental Confirmation relates are as
follows:

	 	 	 
	Trade Date:

	 	[     ]
	Forward Price Adjustment Amount:

	 	USD [     ]
	Hedge Period End Date:

	 	[     ]
	Scheduled Termination Date:

	 	[     ]
	First Acceleration Date:

	 	[     ]
	Prepayment Amount:

	 	[     ]
	Prepayment Date:

	 	[     ]
	Initial Shares:

	 	[     ]
	Initial Share Delivery Date:

	 	[     ]
	Minimum Shares:

	 	As set forth in the Trade Notification, to

be a number of Shares equal to (a) the

Prepayment Amount divided by (b) [     ]% of

the Hedge Period Reference Price.
	Maximum Shares:

	 	As set forth in the Trade Notification, to

be a number of Shares equal to (a) the

Prepayment Amount divided by (b) [     ]% of

the Hedge Period Reference Price.
	Additional Relevant Days:

	 	The 10 Exchange Business Days immediately

following the Termination Date.
	Credit Support Documents.

	 	

3.          Counterparty represents and warrants to Bank that neither it nor any “affiliated
purchaser” (as defined in Rule 10b-18 under the Exchange Act) has made any purchases of blocks
pursuant to the proviso in Rule 10b-18(b)(4) under the Exchange Act during either (i) the four full
calendar weeks immediately preceding the Trade Date or (ii) during the calendar week in which the
Trade Date occurs.

4.          This Supplemental Confirmation may be executed in any number of counterparts, all of
which shall constitute one and the same instrument, and any party hereto may execute this
Supplemental Confirmation by signing and delivering one or more counterparts.

3

IN WITNESS WHEREOF, the parties hereto have caused this Supplemental Confirmation to be
duly executed by their respective authorized officers as of the day and year first written above.

CITIBANK, N.A.

	 	 	 	By:

Name:

Title:

GILEAD SCIENCES, INC.

	 	 	 	By:

Name:

Title:

4

SCHEDULE B

TRADE NOTIFICATION

	 	 	 
	To:

	 	Gilead Sciences, Inc.

333 Lakeside Drive

Foster City, CA 94404
	From:

	 	Citibank, N.A.
	Subject:

	 	Collared Accelerated Stock Buyback
	Date:

	 	[     ]

The purpose of this Trade Notification is to notify you of certain terms in the Transaction
entered into between Citibank, N.A. (“Bank”) and Gilead Sciences, Inc. (“Counterparty”) (together,
the “Contracting Parties”) on the Trade Date specified below.

This Trade Notification supplements, forms part of, and is subject to the Supplemental
Confirmation dated as of [     ], 2008 (the “Supplemental Confirmation”) between the Contracting
Parties, as amended and supplemented from time to time. The Supplemental Confirmation is subject
to the Master Confirmation dated as of October 21, 2008 (the “Master Confirmation”) between the
Contracting Parties, as amended and supplemented from time to time.

	 	 	 
	Hedge Completion Date:

	 	[ ]
	Calculation Period Start Date:

	 	[ ]
	Hedge Period Reference Price:

	 	USD [ ]
	Minimum Shares:

	 	[ ]
	Maximum Shares:

	 	[ ]

Yours sincerely,

CITIBANK, N.A.

	 	 	 	By:

Name:

Title:

5

ANNEX A

COUNTERPARTY SETTLEMENT PROVISIONS

1.          The following Counterparty Settlement Provisions shall apply to the extent
indicated under the Master Confirmation:

	 	 	 	Settlement Currency:                USD

	 	 	 	Settlement Method Election: Applicable; provided that (i) Section 7.1 of the
Equity Definitions is hereby amended by deleting the word “Physical” in the
sixth line thereof and replacing it with the words “Net Share” and (ii) the
Electing Party may make a settlement method election only if the Electing
Party represents and warrants to Bank in writing on the date it notifies
Bank of its election that, as of such date, the Electing Party is not aware
of any material non-public information concerning Counterparty or the Shares
and is electing the settlement method in good faith and not as part of a
plan or scheme to evade compliance with the federal securities laws.

	 	 	 	Electing Party:                           Counterparty

	 	 	 	Settlement Method

	 	 	 	Election Date:                           The Termination Date; provided that if
Bank accelerates the Termination Date pursuant to the proviso to the
definition of “Termination Date,” the Settlement Method Election Date shall
be the second Exchange Business Day immediately following the Termination
Date, and the latest time for making such Settlement Method Election shall
be 10 minutes prior to the open of trading on the Exchange on such second
Exchange Business Day; and provided further that if a Friendly Transaction
Announcement occurs after the Settlement Date, the Settlement Method
Election Date for the Second Settlement shall be the date of the Friendly
Transaction Announcement.

	 	 	 	Default Settlement Method: Cash Settlement

	 	 	 	Forward Cash Settlement

	 	 	 	Amount:                                  The Number of Shares to be Delivered
multiplied by the Settlement Price; provided that in the case of a Second
Settlement occurring after an early termination or cancellation of the
relevant Transaction pursuant to Section 6 of the Agreement or Article 12 of
the Equity Definitions, the Forward Cash Settlement Amount shall equal the
lesser of (i) zero and (ii)(x) the Payment Amount that would have been
calculated for such early termination or cancellation if the words “less
than the Minimum Shares and not” and “,but not below zero,” had been deleted
from the definition of Number of Shares to be Delivered and, for purposes of
“Special Provisions for Counterparty Payments” of the Master Confirmation,
the relevant Friendly Transaction Announcement had occurred prior to such
calculation, as determined by the Calculation Agent (with an amount that
would have been owed by Counterparty expressed as a negative number for
purposes of this calculation) minus (y) the actual Payment Amount calculated
for such early termination or cancellation.

	 	 	 	Settlement Price:                       The average of the VWAP Prices (or, in
the case of a Second Settlement, the Relevant Prices) for the
Exchange Business Days in the Settlement Valuation Period, subject to
Valuation Disruption as specified in the Master Confirmation or, in the case
of a Second Settlement, subject to Section 6.6(a) of the Equity Definitions
as if such dates were Valuation Dates.

	 	 	 	Settlement Valuation Period:   A number of Scheduled Trading Days, not to exceed
5, selected by Bank in its commercially reasonable discretion, beginning on
the Scheduled Trading Day immediately following the Termination Date or, in
the case of a Second Settlement, the date of the Friendly Transaction
Announcement; provided that Bank may determine a higher number of Scheduled
Trading Days as it shall determine in good faith and in a commercially
reasonable manner to be appropriate in light of applicable legal or
regulatory requirements.

	 	 	 	Cash Settlement:                       If Cash Settlement is
applicable, then Buyer shall pay to Seller the absolute value of the Forward
Cash Settlement Amount on the Cash Settlement Payment Date.

	 	 	 	Cash Settlement

	 	 	 	Payment Date:                         The date one Settlement Cycle following the
last day of the Settlement Valuation Period.

	 	 	 	Net Share Settlement

	 	 	 	Procedures:                                If Net Share Settlement is applicable,
Net Share Settlement shall be made in accordance with paragraphs 2 through 7
below.

2.          Net Share Settlement shall be made by delivery on the Cash Settlement Payment Date
of a number of Shares satisfying the conditions set forth in paragraph 3 below (the “Registered
Settlement Shares”), or a number of Shares not satisfying such conditions (the “Unregistered
Settlement Shares”), in either case with a value equal to the absolute value of the Forward Cash
Settlement Amount, with such Shares’ value based on the value thereof to Bank, in each case as
determined by the Calculation Agent.

3.          Counterparty may only deliver Registered Settlement Shares pursuant to
paragraph 2 above if:

(a)         a registration statement covering public resale of the Registered
Settlement Shares by Bank and any other underwriter(s) (the “Registration Statement”) shall have
been filed with the Securities and Exchange Commission under the Securities Act and been declared
or otherwise become effective on or prior to the date of delivery, and no stop order shall be in
effect with respect to the Registration Statement; a printed prospectus relating to the Registered
Settlement Shares (including any prospectus supplement thereto, the “Prospectus”) shall have been
delivered to Bank and any other underwriter(s), in such quantities as Bank shall reasonably have
requested, on or prior to the date of delivery;

(b)         the form and content of the Registration Statement and the Prospectus
(including, without limitation, any sections describing the plan of distribution) shall be
reasonably satisfactory to Bank;

(c)         as of or prior to the date of delivery, Bank and its agents shall have
been afforded a reasonable opportunity to conduct a due diligence investigation with respect to
Counterparty customary in scope for underwritten offerings of equity securities of similar size, as
determined by Bank in its good faith and commercially reasonable discretion, taking into account
market conditions prevailing at that time and conditions and nature of Counterparty at that time
(including, without limitation, if deemed appropriate by Bank, the right to have made available to
them for inspection all financial and other records, pertinent corporate documents and other
information reasonably requested by them), and the results of such investigation are satisfactory
to Bank, in its commercially reasonable discretion; and

(d)         as of the date of delivery, an agreement (the “Underwriting Agreement”)
shall have been entered into with Bank and any other underwriter(s) in connection with the public
resale of the Registered Settlement Shares by Bank and any other underwriter(s) substantially
similar to underwriting agreements customary for underwritten offerings of equity securities of
similar size, in form and substance reasonably satisfactory to Bank, which Underwriting Agreement
shall include, without limitation, provisions substantially similar to those contained in such
underwriting agreements relating, without limitation, to the indemnification of, and contribution
in connection with the liability of, Bank and its affiliates and the provision of customary
opinions, accountants’ comfort letters and lawyers’ negative assurance letters.

4.         If Counterparty delivers Unregistered Settlement Shares pursuant to
paragraph 2 above, then Counterparty covenants as follows:

(a)         all Unregistered Settlement Shares shall be delivered to Bank (or any
affiliate of Bank designated by Bank) and any other initial purchaser(s) pursuant to the exemption
from the registration requirements of the Securities Act provided by Section 4(2) thereof;

(b)         as of or prior to the date of delivery, Bank and any other initial
purchaser(s) and any potential purchaser of any such shares from Bank (or any affiliate of Bank
designated by Bank) or from any other initial purchaser(s) identified by Bank shall be afforded a
commercially reasonable opportunity to conduct a due diligence investigation with respect to
Counterparty customary in scope for private placements of equity securities of similar size, as
determined by Bank in its good faith and commercially reasonable discretion, taking into account
market conditions prevailing at that time and conditions and nature of Counterparty at that time
(including, without limitation, if deemed appropriate by Bank, the right to have made available to
them for inspection all financial and other records, pertinent corporate documents and other
information reasonably requested by them);

(c)         as of the date of delivery, Counterparty shall enter into an agreement
(a “Private Placement Agreement”) with Bank (or any affiliate of Bank designated by Bank) and any
other initial purchaser(s) in connection with the private placement of such shares by Counterparty
to Bank (or any such affiliate) and any other initial purchaser(s) and the private resale of such
shares by Bank (or any such affiliate) and any other initial purchaser(s), substantially similar to
private placement purchase agreements customary for private placements of equity securities of
similar size, in form and substance satisfactory to Bank in its good faith and commercially
reasonable discretion, which Private Placement Agreement shall include, without limitation,
provisions substantially similar to those contained in such private placement purchase agreements
relating, without limitation, to the indemnification of, and contribution in connection with the
liability of, Bank and its affiliates and any other initial purchaser(s) and the provision of
customary opinions, accountants’ comfort letters and lawyers’ negative assurance letters, and shall
provide for the payment by Counterparty of all commercially reasonable fees and expenses in
connection with such resale, including all commercially reasonable fees and expenses of counsel for
Bank and any other initial purchaser(s), and shall contain representations, warranties, covenants
and agreements of Counterparty reasonably necessary or advisable to establish and maintain the
availability of an exemption from the registration requirements of the Securities Act for such
resales; and

(d)         in connection with the private placement of such shares by Counterparty
to Bank (or any such affiliate) and any other initial purchaser(s) and the private resale of such
shares by Bank (or any such affiliate) and any other initial purchaser(s), Counterparty shall, if
so requested by Bank in its good faith and commercially reasonable discretion, prepare, in
cooperation with Bank, a customary private placement memorandum in form and substance reasonably
satisfactory to Bank and any other initial purchaser(s).

5.         Bank, itself or through an affiliate (the “Selling Agent”) or any underwriter(s),
will sell all, or such lesser portion as may be required hereunder, of the Registered Settlement
Shares or Unregistered Settlement Shares and any Makewhole Shares (as defined below) (together, the
“Settlement Shares”) delivered by Counterparty to Bank pursuant to paragraph 6 below commencing on
the Cash Settlement Payment Date and continuing until the date on which the aggregate Net Proceeds
(as such term is defined below) of such sales, as determined by Bank, is equal to the absolute
value of the Forward Cash Settlement Amount (such date, the “Final Resale Date”). If the proceeds
of any sale(s) made by Bank, the Selling Agent or any underwriter(s), net of any fees and
commissions (including, without limitation, underwriting or placement fees) customary for similar
transactions under the circumstances at the time of the offering, together with carrying charges
and expenses incurred in connection with the offer and sale of the Shares (including, but without
limitation to, the covering of any over-allotment or short position (syndicate or otherwise)) (the
“Net Proceeds”) exceed the absolute value of the Forward Cash Settlement Amount, Bank will refund,
in USD, such excess to Counterparty on the date that is three (3) Currency Business Days following
the Final Resale Date, and, if any portion of the Settlement Shares remains unsold, Bank shall
return to Counterparty on that date such unsold Shares.

6.         If the Calculation Agent determines that the Net Proceeds received from
the sale of the Registered Settlement Shares or Unregistered Settlement Shares or any Makewhole
Shares, if any, pursuant to this paragraph 6 are less than the absolute value of the
Forward Cash Settlement Amount (the amount in USD by which the Net Proceeds are less than the
absolute value of the Forward Cash Settlement Amount being the “Shortfall” and the date
on which such determination is made, the “Deficiency Determination Date”), Counterparty shall on
the Exchange Business Day next succeeding the Deficiency Determination Date (the “Makewhole Notice
Date”) deliver to Bank, through the Selling Agent, a notice of Counterparty’s election that
Counterparty shall either (i) pay an amount in cash equal to the Shortfall on the day that is one
(1) Currency Business Day after the Makewhole Notice Date, or (ii) deliver additional Shares. If
Counterparty elects to deliver to Bank additional Shares, then Counterparty shall deliver
additional Shares in compliance with the terms and conditions of paragraph 3 or paragraph 4 above,
as the case may be (the “Makewhole Shares”), on the first Clearance System Business Day which is
also an Exchange Business Day following the Makewhole Notice Date in such number as the Calculation
Agent reasonably believes would have a market value on that Exchange Business Day equal to the
Shortfall. Such Makewhole Shares shall be sold by Bank and any other underwriter(s) or initial
purchaser(s) in accordance with the provisions above; provided that if the sum of the Net Proceeds
from the sale of the originally delivered Shares and the Net Proceeds from the sale of any
Makewhole Shares is less than the absolute value of the Forward Cash Settlement Amount
then Counterparty shall, at its election, either make such cash payment or deliver to Bank further
Makewhole Shares until such Shortfall has been reduced to zero.

7.         Notwithstanding the foregoing, in no event shall the aggregate number of Settlement
Shares and Makewhole Shares be greater than the Reserved Shares minus the amount of any Shares
actually delivered by Counterparty under any other Transaction(s) under this Master Confirmation
(the result of such calculation, the “Capped Number”). Counterparty represents and warrants (which
shall be deemed to be repeated on each day that a Transaction is outstanding) that the Capped
Number is equal to or less than the number of Shares determined according to the following formula:

A – B

	 	 	 	Where   A = the number of authorized but unissued shares of the Counterparty that
are not reserved for future issuance on the date of the determination of the
Capped Number; and

B = the maximum number of Shares required to be delivered to third parties
if Counterparty elected Net Share Settlement of all transactions in the
Shares (other than Transactions in the Shares under this Master
Confirmation) with all third parties that are then currently outstanding and
unexercised.

“Reserved Shares” means initially, 27,000,000 Shares. The Reserved Shares may be increased or
decreased in a Supplemental Confirmation.

6

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