Document:

Amended and Restated Investors Rights' Agreement dated 10/8/03.

 EXHIBIT 10.7 
  
 COTHERIX, INC. 
  
 Second Amended and Restated Investor Rights Agreement 
  
 This Second Amended and Restated Investor Rights Agreement (this “Agreement”), dated as of October 8, 2003, is entered into by and among
(i) CoTherix, Inc., a Delaware corporation (the “Company”), (ii) the holders of Preferred Stock of the Company listed on Schedule A attached hereto and (iii) the holders of Common Stock of the Company listed on Schedule
B attached hereto. 
  
 RECITALS 
  
 WHEREAS, in connection with the consummation of the transactions contemplated
by that certain Series B Stock Purchase Agreement, as amended, entered into by and among the Company and certain of the Existing Preferred Investors (as defined below), the Existing Preferred Investors entered into an Amended and Restated Investor
Rights Agreement, dated as of April 5, 2001, as amended, (the “Prior Investor Rights Agreement”), with the Company and the Founders (as defined below); 
  
 WHEREAS, pursuant to that certain Series C Preferred Stock Purchase Agreement, of even date herewith (the “Series C
Purchase Agreement”), the Company has agreed to sell and issue to MPM BioVentures III, L.P. (“MPM”), Thomas Weisel Healthcare Venture Partners, L.P., Frazier Healthcare IV, L.P. (“Frazier”), and/or certain
affiliates of the foregoing, and certain Existing Preferred Investors (collectively, the “Series C Investors”) up to an aggregate of 47,826,161 shares of the Company’s Series C Convertible Preferred Stock, $0.001 par value per
share (the “Series C Preferred Stock”); 
  
 WHEREAS, to induce the Series C Investors to enter into the Series C Purchase Agreement and purchase the Series C Preferred Stock pursuant to the terms and conditions thereof, the Company and the undersigned Existing Preferred Investors,
Founders and Columbia (each as defined below) desire to amend and restate the Prior Investor Rights Agreement pursuant to Section 6.7(b) thereof and to enter into this Agreement (the terms of this Agreement to supersede the terms of the Prior
Investor Rights Agreement in their entirety); and 
  
 WHEREAS, it
is a condition precedent to the consummation by the Series C Investors of their respective obligations under the Series C Purchase Agreement that the parties hereto enter into this Agreement. 
  
 AGREEMENT 
  
 NOW, THEREFORE, in consideration of the mutual promises and covenants contained in this Agreement, and the consummation of
the sale and purchase of the Series C Preferred Stock pursuant to the Series C Purchase Agreement and for other valuable consideration, receipt of which is hereby acknowledged, the parties hereto agree as follows: 

 ARTICLE I 
 DEFINITIONS 
  
 As used in this
Agreement, the following terms shall have the following respective meanings: 
  
 “Certificate of Incorporation” means the Fourth Amended and Restated Certificate of Incorporation of the Company, as amended from time to time. 
  
 “Columbia” means The Trustees of Columbia University in the
City of New York. 
  
 “Commission” means the
United States Securities and Exchange Commission, or any other federal agency at the time administering the Securities Act. 
  
 “Common Stock” shall mean the shares of Common Stock, $0.001 par value per share, of the Company 
  
 “Common Stock Purchase Agreement” shall mean that certain
Common Stock Purchase Agreement dated as of October 8, 2003 by and among the Company and the investors set forth on the Schedule of Investors, attached as Schedule A thereto. 
  
 “Co-Sale Agreement” means that certain Second Amended and Restated Right of First Refusal and Co-Sale
Agreement, of even date herewith, by and among the Company, Columbia, the Preferred Investors and the Founders. 
  
 “Exchange Act” means the Securities Exchange Act of 1934, as amended, or any similar federal statute, and the rules and regulations of
the Commission issued under such Act, as they each may, from time to time, be in effect. 
  
 “Founder” means each of Dr. Jerome Cantor, Donald Santel and Dr. Gerard Turino. The foregoing are collectively referred to herein as the “Founders.” 
  
 “Liquidation Event” shall have the meaning of such term as
set forth in Section 2(d) of Article IV of the Fourth Amended and Restated Certificate of Incorporation, as amended from time to time. 
  
 “Person” means any individual, partnership, corporation, limited liability company, trust or unincorporated organization, or a government
or agency or political subdivision thereof. 
  
 “Preferred
Investors” means collectively, the holders of Preferred Stock. 
  
 “Preferred Stock” means, collectively, the Series A Preferred Stock, the Series B Preferred Stock and the Series C Preferred Stock. 

 “Qualified Initial Public Offering” means the sale of shares of Common Stock in a firm
commitment underwritten public offering to be listed on the Nasdaq National Market or the New York Stock Exchange pursuant to a Registration Statement at a price to the public of at least $3.50 per share (adjusted for stock splits, stock dividends
and similar events) and resulting in proceeds (net of the underwriting discounts or commissions and offering expenses) to the Company of at least $50,000,000. 
  

“Registrable Shares” means (i) the shares of Common Stock issued or issuable upon conversion of the Preferred Stock, (ii) shares of
Common Stock held from time to time by the Founders and 1,498,300 shares of Common Stock in the aggregate held by Sofinnova Venture Partners V, LP, Alta California Partners III, L.P., The Spray Venture Fund, L.P., Walnut Street Partners, LLC and
Biotechnology Development Fund II, L.P. or affiliates of each of the foregoing issued pursuant to the Common Stock Purchase Agreement, (iii) shares of Common Stock held from time to time by Columbia, (iv) any shares of Common Stock, and any shares
of Common Stock issued or issuable upon the conversion or exercise of any other securities, acquired by the Preferred Investors pursuant to Article IV of this Agreement or by the Preferred Investors or Columbia pursuant to the Co-Sale Agreement, and
(v) any other shares of Common Stock issued in respect of such shares (because of stock splits, stock dividends, reclassifications, recapitalizations, or similar events); provided, however, that shares of Common Stock which are
Registrable Shares shall cease to be Registrable Shares (a) with respect to any Stockholder, at such time as such Stockholder holds less than one percent (1%) of the Company’s outstanding Common Stock and is otherwise eligible to sell all of
such Stockholder’s Registrable Shares under Rule 144 under the Securities Act within a three-month period, (b) upon any sale of such shares in any manner to a person or entity which is not entitled to the rights provided by this Agreement, or
(c) upon any sale of such shares pursuant to a Registration Statement or Rule 144 under the Securities Act. Wherever reference is made in this Agreement to a request or consent of holders of a certain percentage of Registrable Shares, the
determination of such percentage shall include shares of Common Stock issuable upon conversion of the Shares even if such conversion has not yet been effected. 
  

“Registration Statement” means a registration statement filed by the Company with the Commission for a public offering and sale of
Common Stock by the Company (other than a registration statement on Form S-8 or Form S-4, or their successors, or any other form for a similar limited purpose, or any registration statement covering only securities proposed to be issued in exchange
for securities or assets of another corporation, including without limitation, a registration relating to a transaction under Rule 145 of the Securities Act). 
  

“Securities Act” means the Securities Act of 1933, as amended, or any similar federal statute, and the rules and regulations of the
Commission issued under such Act, as they each may, from time to time, be in effect. 
  
 “Series A Preferred Stock” shall mean the shares of Series A Convertible Preferred Stock, $0.001 par value per share, of the Company. 
  
 “Series B Preferred Stock” shall mean the shares of Series B Convertible Preferred Stock, $0.001 par value
per share, of the Company. 

 “Shares” means the Series A Preferred Stock, the Series B Preferred Stock, the Series C
Preferred Stock and in the case of Columbia and the Founders, the Common Stock. 
  
 “Stockholders” means the Preferred Investors, the Founders, Columbia and any other Person to whom the rights granted under this Agreement are transferred by any party hereto, its successors or
permitted assigns pursuant to the provisions hereof. 
  
 In
addition, the following terms as used herein shall have the meanings assigned to such terms in the Sections referenced below: 
  

			
	 “Available Undersubscription Amount”
	  	Section 4.1(b)
	 “Demand Registration”
	  	Section 3.1(a)
	 “Frazier”
	  	Recitals
	 “GAAP”
	  	Section 2.1
	 “Indemnified Party”
	  	Section 3.5(c)
	 “Indemnifying Party”
	  	Section 3.5(c)
	 “Notice of Acceptance”
	  	Section 4.1(b)
	 “Major Preferred Investor”
	  	Section 4.1(a)
	 “MPM”
	  	Recitals
	 “Offer”
	  	Section 4.1(a)
	 “Offered Securities”
	  	Section 4.1
	 “Prior Investor Rights Agreement”
	  	Recitals
	 “Refused Securities”
	  	Section 4.1(c)
	 “Registration Expenses”
	  	Section 3.4
	 “S-3 Registration”
	  	Section 3.1(b)
	 “Series C Investors”
	  	Recitals
	 “Series C Preferred Stock”
	  	Recitals
	 “Series C Purchase Agreement”
	  	Recitals
	 “Series C Right of First Refusal and Co-Sale Agreement”
	  	Section 5.3(h)
	 “Signature Pages”
	  	Section 5.3(h)
	 “Undersubscription Amount”
	  	Section 4.1(a)

  
 ARTICLE II 

INFORMATION RIGHTS 
  
 2.1 Delivery of Financial Statements. The Company shall deliver to (i) Columbia, for so long as Columbia holds at least seventy-five thousand
(75,000) shares of Common Stock (as adjusted for subsequent stock splits, stock dividends, combinations and other recapitalizations) and (ii) each Preferred Investor, for so long as each such Preferred Investor holds at least seventy-five thousand
(75,000) shares of Preferred Stock (as adjusted for subsequent stock splits, stock dividends, combinations and other recapitalizations): 
  
 (a) as soon as practicable, but in any event within one hundred twenty (120) days after the end of each fiscal year of the Company, an
income statement for such fiscal 

 
year, a balance sheet of the Company and statement of stockholder’s equity as of the end of such fiscal year, and a statement of cash flows for such
fiscal year, such year-end financial reports to be in reasonable detail, prepared in accordance with generally accepted accounting principles (“GAAP”), and audited and certified by independent public accountants of nationally
recognized standing selected by the Company; 
  
 (b) within thirty (30) days of the end of each month, an unaudited income statement and statement of cash flows for such month, a balance sheet for and as of the end of such month, and a report setting forth the comparison of such month
unaudited statements to the statements for the same month in the previous year and projected results for such month on a monthly and year to date basis, all in reasonable detail; 
  
 (c) with respect to the financial statements called for in subsection (b) of this Section 2.1, an instrument
executed by the Chief Financial Officer or President of the Company and certifying that such financial statements were prepared in accordance with GAAP consistently applied with prior practice for earlier periods (with the exception of footnotes
that may be required by GAAP) and fairly present the financial condition of the Company and its results of operation for the period specified, subject to year-end audit adjustment; and 
  
 (d) such other information relating to the financial condition, business, prospects or corporate affairs of
the Company as Columbia or the Preferred Investors may from time to time reasonably request; provided, however, that the Company shall not be obligated under this subsection (d) or any other subsection of Section 2.1 to provide
information that it deems in good faith to be a trade secret or confidential information. 
  
 (e) The Company shall deliver to each member of the Company’s Board of Directors and Columbia, as soon as practicable, but in any
event thirty (30) days prior to the end of each fiscal year, a budget and business plan for the next fiscal year, prepared on a monthly basis, including balance sheets and income statements for such months and, as soon as prepared, any other budgets
or revised budgets prepared by the Company. The Company shall also provide to each member of the Board of Directors with (i) copies of any public filings by the Company made with the Commission, if any and (ii) notification of any material
litigation or credible threat thereof to which the Company is or may become a party. 
  
 2.2 Inspection. The Company shall permit Columbia and each Preferred Investor upon reasonable request, at Columbia’s or such Preferred Investor’s (as the case may be) expense, to visit and inspect the
Company’s properties, to examine its books of account and records and to discuss the Company’s affairs, finances and accounts with its officers, all at such reasonable times as may be reasonably requested by Columbia or any Preferred
Investor; provided, however, that the Company shall not be obligated pursuant to this Section 2.2 to provide access to any information which it reasonably considers to be a trade secret or confidential information. 
  
 2.3 Confidentiality, Assignment and Termination of Covenants.

 (a) Columbia hereby agrees to hold in confidence and trust and to act in a fiduciary
manner with respect to all information so provided and to use its best efforts to ensure that any third party to which it provides Company information pursuant to this Section 2.3(a) shall hold such information in confidence and trust. 

 
 (b) The covenants set forth in this Section 2 shall
terminate as to Columbia and be of no further force or effect when the Company first becomes subject to the periodic reporting requirements of Sections 12(g) or 15(d) of the Exchange Act, whichever event shall first occur. 
  
 (c) The covenants set forth in this Section 2 may be
assigned (but only with all related obligations) by a Stockholder to any transferee or assignee of such Stockholder’s Shares who (i) acquires at least seventy-five thousand (75,000) shares of Registrable Shares (subject to appropriate
adjustment for stock splits, stock dividends, combinations and other recapitalizations) from such Stockholder, (ii) otherwise holds at least seventy-five thousand (75,000) shares of Registrable Shares (subject to appropriate adjustment for stock
splits, stock dividends, combinations and other recapitalizations), or (iii) is an affiliate of the transferring Stockholder. 
  
 ARTICLE III 
 REGISTRATION RIGHTS 
  
 3.1 Required Registrations. 
  
 (a) At any time after 180 days following the closing of the
Company’s first underwritten public offering of shares of Common Stock pursuant to a Registration Statement, (i) Stockholders (other than the Founders and Columbia) holding in the aggregate at least 50% of the Registrable Shares held by the
Stockholders (other than the Founders and Columbia), or (ii) Stockholders (other than the Founders and Columbia) holding Registrable Shares having an aggregate offering price of not less than $20,000,000 (based on the public market price estimated
in good faith by the Company’s Board of Directors and net of any underwriting discounts and commissions), may request, in writing, that the Company effect the registration on Form S-1 or Form S-2 (or any successor form) of Registrable Shares
owned by such Stockholders (other than Founders or Columbia) (such registration, a “Demand Registration”). Thereupon, the Company shall, within ten (10) days of the receipt of the request, give written notice of such request to all
Stockholders (other than the Founders and Columbia) and shall, as expeditiously as possible, use its best efforts to effect the registration on Form S-1 or Form S-2 (or any successor form) of all Registrable Shares which the Stockholders (other than
the Founders and Columbia) request to be registered within twenty (20) days of the mailing of such notice by the Company. 
  
 (b) At any time after the Company becomes eligible to file a Registration Statement on Form S-3 (or any successor form relating to
secondary offerings), a Stockholder or Stockholders may request the Company, in writing, to effect the registration on Form S-3 (or such successor form), of Registrable Shares having an aggregate offering price greater than $1,000,000 (based on the
public market price at the time of such request) (such registration, an “S-3 Registration”). Thereupon, the Company shall, within ten (10) days of the receipt of the request, give written notice of such request to all Stockholders
(other than the Founders and 

 
Columbia) and shall, as expeditiously as possible, use its best efforts to effect the registration on Form S-3 (or such successor form) of all Registrable
Shares which the Stockholders (other than the Founders and Columbia) request to be registered within twenty (20) days of the mailing of such notice by the Company. 
  
 (c) Notwithstanding the foregoing, with respect to Demand Registrations, the Company shall not be required
to (i) effect more than two Demand Registrations pursuant to paragraph (a) above or (ii) effect any Demand Registrations during the 90 day period following the effective date of any prior Registration Statement, and no registration pursuant to
paragraph (a) above shall be considered a Demand Registration hereunder unless at least 80% of the Registrable Shares which the Stockholders request to be registered in such registration are actually registered and sold in such registration.

  
 (d) Notwithstanding the foregoing, with
respect to S-3 Registrations, the Company shall not be required to the more than two S-3 Registrations pursuant to paragraph (b) above in any twelve (12) month period. 
  
 (e) If at the time of any request to register Registrable Shares pursuant to this Section 3.1, the Company
is engaged or has plans to engage, within 90 days of the time of the request, in a registered public offering of securities for its own account or is engaged in any other activity which, in the good faith determination of the Company’s Board of
Directors, would be adversely affected by the requested registration to the material detriment of the Company, then the Company may at its option direct that such request be delayed for a period not in excess of 90 days from the effective date of
such offering or the date of commencement of such other material activity, as the case may be, such right to delay a request to be exercised by the Company not more than once in any 12 month period. 
  
 (e) Stockholders holding a majority of the Registrable
Securities to be included in any Demand Registration or S-3 Registration shall determine whether or not such Demand Registration or S-3 Registration shall be underwritten. If such Stockholders intend to distribute the Registrable Shares in a Demand
Registration or S-3 Registration by means of an underwriting, they shall so advise the Company in their request for such Demand Registration or S-3 Registration, whereupon the Company shall select investment banker(s) and managing underwriter(s)
which are reasonably acceptable to such Stockholders to administer such offering. If the underwriter chosen to underwrite any Demand Registration or S-3 Registration advises the Company and the participating Stockholders (other than the Founders and
Columbia) in writing that marketing factors require a limitation of the number of shares to be underwritten, then the number of Registrable Shares that may be included in the underwriting shall be allocated among all Stockholders participating in
that underwritten offering in proportion (as nearly as practicable) to the amount of Registrable Shares of the Company seeking to be registered by each such Stockholder; provided, however, that the number of Registrable Shares to be included in such
underwriting shall not be reduced unless all other securities are first entirely excluded from the underwriting. 

 3.2 Incidental Registrations. 
  
 (a) Whenever the Company proposes to file a Registration Statement, it will, prior to such filing, give
written notice to all Stockholders of its intention to do so and, upon the written request of a Stockholder or Stockholders, given within ten (10) business days after the Stockholders receive such notice, the Company shall use its best efforts to
cause all Registrable Shares which the Company has been requested by such Stockholder or Stockholders to register, to be registered under the Securities Act to the extent necessary to permit their sale or other disposition in accordance with the
intended methods of distribution specified in the request of such Stockholder or Stockholders; provided, however, that the Company shall have the right to postpone or withdraw any registration effected pursuant to this Section 3.2
without obligation to any Stockholder. 
  
 (b) In
connection with any registration under this Section 3.2 involving an underwriting, the Company shall not be required to include any Registrable Shares in such registration unless the holders thereof accept the terms of the underwriting as agreed
upon between the Company and the underwriters selected by it. If, in connection with the Company’s initial public offering, the managing underwriter determines in its sole discretion that it is desirable because of marketing factors to limit
the number of Registrable Shares to be included in the Company’s initial public offering, then the Company shall be required to include in the registration only that number of Registrable Shares, if any, which the managing underwriter believes
should be included therein; provided, however, that, regardless of any registration rights the Company may grant after the date hereof, no persons or entities other than the Company or the Stockholders shall be permitted to include
securities in the offering. If the number of Registrable Shares to be included in the Company’s initial public offering in accordance with the foregoing is less than the total number of shares which the holders of Registrable Shares have
requested to be included, then the holders of Registrable Shares who have requested registration shall participate in the registration pro rata based upon their total ownership of shares of Common Stock (giving effect to the conversion into Common
Stock of all securities convertible thereinto). If any holder would thus be entitled to include more securities than such holder requested to be registered, the excess shall be allocated among other requesting holders pro rata in the manner
described in the preceding sentence. If the managing underwriter of any subsequent public offerings determines in its sole discretion that it is desirable because of marketing factors to limit the number of Registrable Shares to be included in such
other offering, then the Company shall only be required to include in such offering so many of the Registrable Shares as the managing underwriter believes will not jeopardize the success of the offering (the Registrable Shares so included to be
apportioned pro rata among the participating Stockholders according to the total amount of Registrable Shares owned by such participating Stockholders) provided that, notwithstanding any registration rights the Company may grant after the date
hereof, no reduction in the number of Registrable Securities the participating Stockholders have requested to be included in such offering shall limit the number of Registrable Shares being offered pursuant to such registration for the account of
the participating Stockholders to less than 20% of the aggregate shares offered under such offering; provided, further that such percentage may be decreased by the prior written consent of the Investors holding at least a majority of
the Registrable Shares held by the Investors. 

 3.3 Registration Procedures. If and whenever the Company is required by the provisions of this
Agreement to use its best efforts to effect the registration of any of the Registrable Shares under the Securities Act, the Company shall: 
  
 (a) file with the Commission a Registration Statement with respect to such Registrable Shares and use its best efforts to cause that
Registration Statement to become effective; 
  
 (b) as expeditiously as possible prepare and file with the Commission any amendments and supplements to the Registration Statement and the prospectus included in the Registration Statement as may be necessary to keep the Registration
Statement effective, in the case of a firm commitment underwritten public offering, until each underwriter has completed the distribution of all securities purchased by it and, in the case of any other offering, until the earlier of the sale of all
Registrable Shares covered thereby or ninety (90) days after the effective date thereof; 
  
 (c) as expeditiously as possible furnish to each selling Stockholder such reasonable numbers of copies of the prospectus, including a
preliminary prospectus, in conformity with the requirements of the Securities Act, and such other documents as the selling Stockholder may reasonably request in order to facilitate the public sale or other disposition of the Registrable Shares owned
by the selling Stockholder; 
  
 (d) as
expeditiously as possible use commercially reasonable efforts to register or qualify the Registrable Shares covered by the Registration Statement under the securities or Blue Sky laws of such states as the selling Stockholder shall reasonably
request, and do any and all other acts and things that may be necessary or desirable to enable the selling Stockholder to consummate the public sale or other disposition in such states of the Registrable Shares owned by the selling Stockholder;
provided, however, that the Company shall not be required in connection with this paragraph (d) to qualify as a foreign corporation or execute a general consent to service of process in any jurisdiction; 
  
 (e) notify each holder of Registrable Shares covered by such
registration statement at any time when a prospectus relating thereto is required to be delivered under the Securities Act of the happening of any event as a result of which the prospectus included in such registration statement, as then in effect,
includes an untrue statement of a material fact or omits to state a material fact required to be stated therein or necessary to make the statements therein not misleading in the light of the circumstances then existing; 
  
 (f) cause all such Registrable Shares registered pursuant
hereunder to be listed on each securities exchange on which similar securities issued by the Company are then listed; 
  
 (g) provide a transfer agent and registrar for all Registrable Shares registered pursuant hereunder and a CUSIP number for all such
Registrable Shares, in each case not later than the effective date of such registration; and 

 (h) furnish, at the request of any Stockholder requesting registration of Registrable
Shares pursuant to this Article III on the date that such Registrable Shares are delivered to the underwriters for sale in connection with a registration pursuant to this Article III, if such securities are being sold through underwriters, or, if
such securities are not being sold through underwriters, on the date that the registration statement with respect to such securities becomes effective, (i) an opinion, dated such date, of the counsel representing the Company for the purposes of such
registration, in form and substance as is customarily given to underwriters in an underwritten public offering, addressed to the underwriters, if any, and to the Stockholders requesting registration of Registrable Shares and (ii) a letter dated such
date, from the independent certified public accountants of the Company, in form and substance as is customarily given by independent certified public accountants to underwriters in an underwritten public offering, addressed to the underwriters, if
any, and to the Stockholders requesting registration of Registrable Shares. 
  
 If the Company has delivered preliminary or final prospectuses to the selling Stockholders and after having done so the prospectus is amended to comply with the requirements of the Securities Act, the Company shall
promptly notify the selling Stockholders and, if requested, the selling Stockholder shall immediately cease making offers of Registrable Shares and return all prospectuses to the Company. The Company shall promptly provide each selling Stockholder
with revised prospectuses and, following receipt of the revised prospectuses, the selling Stockholder shall be free to resume making offers of the Registrable Shares. 
  
 Notwithstanding the foregoing, each selling Stockholder shall cease making offers or sales pursuant to a “shelf”
Registration Statement during any period (not to exceed 120 days) in which the Company determines, by notice to each selling Stockholder, that it is in possession of material non-public information that, for valid business reasons, it wishes to keep
confidential. 
  
 If, after a Registration Statement becomes
effective, the Company becomes engaged in any activity which, in the good faith determination of the Company’s Board of Directors, involves information that would have to be disclosed in the Registration Statement but which the Company desires
to keep confidential for valid business reasons, then the Company may at its option, by notice to such Stockholders, require that the Stockholders who have included Registrable Shares in such Registration Statement cease sales of such Registrable
Shares under such Registration Statement for a period not in excess of four (4) months from the date of such notice, such right to be exercised by the Company not more than twice in any 12-month period. If, in connection therewith, the Company
considers it appropriate for such Registration Statement to be amended, the Company shall so amend such Registration Statement as promptly as practicable and such Stockholders shall suspend any further sales of their Registrable Shares until the
Company advises them that such Registration Statement has been amended. The time periods referred to herein during which such Registration Statement must be kept effective shall be extended for an additional number of days equal to the number of
days during which the right to sell Registrable Shares was suspended pursuant to this or the preceding paragraph. 

 3.4 Allocation of Expenses. The Company will pay all Registration Expenses of all registrations
under this Agreement. For purposes of this Section 3.4, the term “Registration Expenses” shall mean all expenses incurred in complying with Section 3.1 and Section 3.2, including, without limitation, all registration and filing fees,
exchange listing fees, printing expenses, fees and expenses of counsel for the Company, state Blue Sky fees and expenses, the expense of any special audits incident to or required by any such registration, and the fees and expenses of one counsel to
the selling Stockholders not to exceed $25,000 but excluding underwriting discounts, selling commissions and the fees and expenses of selling Stockholders’ own counsel in excess of that stated above. 
  
 3.5 Indemnification and Contribution. 
  
 (a) In the event of any registration of any of the
Registrable Shares under the Securities Act pursuant to this Agreement, the Company will indemnify and hold harmless the seller of such Registrable Shares, each underwriter of such Registrable Shares, and each other person, if any, who controls such
seller or underwriter within the meaning of the Securities Act or the Exchange Act against any losses, claims, damages or liabilities, joint or several, to which such seller, underwriter or controlling person may become subject under the Securities
Act, the Exchange Act, state securities or Blue Sky laws or otherwise, insofar as such losses, claims, damages or liabilities (or actions in respect thereof) arise out of or are based upon any untrue statement or alleged untrue statement of any
material fact contained in any Registration Statement under which such Registrable Shares were registered under the Securities Act, any preliminary prospectus or final prospectus contained in the Registration Statement, or any amendment or
supplement to such Registration Statement, or arise out of or are based upon the omission or alleged omission to state a material fact required to be stated therein or necessary to make the statements therein not misleading or any violation or
alleged violation by the Company of the Securities Act, the Exchange Act, any state securities law or any rule or regulation promulgated under the Securities Act, the Exchange Act or any state securities law; and the Company will reimburse such
seller, underwriter and each such controlling person for any legal or any other expenses as they are reasonably incurred by such seller, underwriter or controlling person in connection with investigating or defending any such loss, claim, damage,
liability or action; provided, however, that the Company will not be liable in any such case to a seller, underwriter or controlling person to the extent that any such loss, claim, damage or liability arises out of or is based upon any
untrue statement or omission made in such Registration Statement, preliminary prospectus or final prospectus, or any such amendment or supplement, in reliance upon and in conformity with information furnished to the Company, in writing, by or on
behalf of such seller, underwriter or controlling person specifically for use in the preparation thereof, or if, in the case of a sale directly by such holder of Registrable Shares (including a sale of such Registrable Shares through any underwriter
retained by such holder of Registrable Shares to engage in a distribution solely on behalf of such holder of Registrable Shares), such untrue statement or alleged untrue statement or omission or alleged omission was contained in a preliminary
prospectus and corrected in a final or amended prospectus, and such holder of Registrable Shares failed to deliver a copy of the final or amended prospectus at or prior to the confirmation of the sale of the Registrable Shares to the person
asserting any such loss, claim, damage or liability in any case where such delivery is required by the Securities Act or any state securities laws. 

 (b) In the event of any registration of any of the Registrable Shares under the
Securities Act pursuant to this Agreement, each seller of Registrable Shares, severally and not jointly, will indemnify and hold harmless the Company, each of its directors and officers and each underwriter (if any) and each person, if any, who
controls the Company or any such underwriter within the meaning of the Securities Act or the Exchange Act, against any losses, claims, damages or liabilities, joint or several, to which the Company, such directors and officers, underwriter or
controlling person may become subject under the Securities Act, Exchange Act, state securities or Blue Sky laws or otherwise, insofar as such losses, claims, damages or liabilities (or actions in respect thereof) arise out of or are based upon any
untrue statement or alleged untrue statement of a material fact contained in any Registration Statement under which such Registrable Shares were registered under the Securities Act, any preliminary prospectus or final prospectus contained in the
Registration Statement, or any amendment or supplement to the Registration Statement, or arise out of or are based upon any omission or alleged omission to state a material fact required to be stated therein or necessary to make the statements
therein not misleading, if the statement or omission was made in reliance upon and in conformity with information relating to such seller furnished in writing to the Company by or on behalf of such seller specifically for use in connection with the
preparation of such Registration Statement, prospectus, amendment or supplement, provided, however, that the seller of Registrable Shares will not be liable in any such case to the Company, any director, officer, underwriter or to any
other person subject to indemnification pursuant to this Section 3.5(b) to the extent that (i) any such loss, claim, damage or liability arises out of or is based upon any untrue statement or alleged untrue statement or omission or alleged omission
made in a preliminary prospectus and corrected in a final or amended prospectus, where the party (other than the selling Stockholder) that provided such preliminary or other prospectus, or any amendment or supplement thereto containing the untrue
statement or alleged untrue statement or omission or alleged omission failed to deliver a copy of the final or amended prospectus at or prior to the confirmation of the sale of the Registrable Shares to the person asserting any such loss, claim,
damage or liability in any case where such delivery is required by the Securities Act or any state securities laws and (ii) amounts are paid in settlement of any such loss, claim, damage, liability or action if such settlement is effected without
the consent of the seller of Registrable Securities, which consent shall not be unreasonably withheld; and provided, further, however, that, in no event shall any indemnity under this subsection 3.5(b) exceed the net proceeds
from the offering received by such selling Stockholder. 
  
 (c) Each party entitled to indemnification under this Section 3.5 (the “Indemnified Party”) shall give notice to the party required to provide indemnification (the “Indemnifying
Party”) promptly after such Indemnified Party has actual knowledge of any claim as to which indemnity may be sought, and shall permit the Indemnifying Party to assume the defense of any such claim or any litigation resulting
therefrom; provided, that counsel for the Indemnifying Party, who shall conduct the defense of such claim or litigation, shall be approved by the Indemnified Party (whose approval shall not be unreasonably withheld); and, provided
further, that the failure of any Indemnified Party to give notice as provided herein shall not relieve the Indemnifying Party of its obligations under this Section 3.5, unless and except to the extent that the Indemnifying Party is prejudiced
by the failure of the Indemnified Party to provide timely notice. The Indemnified Party may participate in such defense at such party’s 

 
expense; provided, however, that the Indemnifying Party shall pay such expense if representation of such Indemnified Party by the counsel
retained by the Indemnifying Party would be inappropriate due to actual or potential differing interests between the Indemnified Party and any other party represented by such counsel in such proceeding. No Indemnifying Party, in the defense of any
such claim or litigation shall, except with the consent of each Indemnified Party, consent to entry of any judgment or enter into any settlement which does not include as an unconditional term thereof the giving by the claimant or plaintiff to such
Indemnified Party of a release from all liability in respect of such claim or litigation, and no Indemnified Party shall consent to entry of any judgment or settle such claim or litigation without the prior written consent of the Indemnifying Party.

  
 (d) In order to provide for just and
equitable contribution to joint liability under the Securities Act in any case in which either (i) any holder of Registrable Shares exercising rights under this Agreement, or any controlling person of any such holder, makes a claim for
indemnification pursuant to this Section 3.5 but it is judicially determined (by the entry of a final judgment or decree by a court of competent jurisdiction and upon the expiration of time to appeal or the denial of the last right of appeal) that
such indemnification may not be enforced in such case notwithstanding the fact that this Section 3.5 provides for indemnification in such case, or (ii) contribution under the Securities Act may be required on the part of any such selling Stockholder
or any such controlling person in circumstances for which indemnification is provided under this Section 3.5; then, in each such case, the Company and such Stockholder will contribute to the aggregate losses, claims, damages or liabilities to which
they may be subject (after contribution from others) in such proportions so that such holder is responsible for the portion represented by the percentage that the public offering price of its Registrable Shares offered by the Registration Statement
bears to the public offering price of all securities offered by such Registration Statement, and the Company is responsible for the remaining portion; provided, however, that, in any such case, (A) no such holder will be required to
contribute any amount in excess of the net proceeds to it of all Registrable Shares sold by it pursuant to such Registration Statement, and (B) no person or entity guilty of fraudulent misrepresentation, within the meaning of Section 11(f) of the
Securities Act, shall be entitled to contribution from any person or entity who is not guilty of such fraudulent misrepresentation. If the contribution amounts provided for in this Section 3.5(d) are held by a court of competent jurisdiction to be
unavailable or otherwise inappropriate, then the Indemnifying Party, in lieu thereof, shall contribute to the amount paid or payable by such Indemnified Party as a result of such loss, liability, claim, damage, or expense in
such proportion as is appropriate to reflect the relative fault of the Indemnifying Party on the one hand and of the Indemnified Party on the other in connection with the statements or omissions that resulted in such loss, liability, claim, damage,
or expense as well as any other relevant equitable considerations. The relative fault of the Indemnifying Party and of the Indemnified Party shall be determined by reference to, among other things, whether the untrue or alleged untrue statement of a
material fact or omission to state a material fact relates to information supplied by the Indemnifying Party or by the Indemnified Party and such parties’ relative intent, knowledge, access to information, and opportunity to correct or prevent
such statement or omission. 

 (e) Notwithstanding the foregoing, to the extent that the provisions on indemnification
and contribution contained in an underwriting agreement entered into in connection with any underwritten public offering are in conflict with the foregoing provisions, the provisions in the underwriting agreement shall control; and 
  
 (f) The obligations of the Company and Stockholders under
this Section 3.5 shall survive the completion of any offering of Registrable Shares in a registration statement under this Article 3, and otherwise. 
  
 3.6 Indemnification with Respect to Underwritten Offering. In the event that Registrable Shares are sold pursuant to a Registration Statement in an
underwritten offering pursuant to Section 3.1, the Company agrees to enter into an underwriting agreement containing customary representations and warranties with respect to the business and operations of an issuer of the securities being registered
and customary covenants and agreements to be performed by such issuer, including without limitation customary provisions with respect to indemnification by the Company of the underwriters of such offering. 
  
 3.7 Information by Holder. Each Stockholder including Registrable
Shares in any registration shall furnish to the Company such information regarding such Stockholder and the distribution proposed by such Stockholder as the Company may reasonably request in writing and as shall be required in connection with any
registration, qualification or compliance referred to in this Agreement. 
  
 3.8 Rule 144 Requirements. After the earliest of (a) the closing of the sale of securities of the Company pursuant to a Registration Statement, (b) the registration by the Company of a class of securities under
Section 12 of the Exchange Act, or (c) the issuance by the Company of an offering circular pursuant to Regulation A under the Securities Act, the Company agrees to: 
  
 (i) comply with the requirements of Rule 144(c) under the Securities Act with respect to current public
information about the Company; 
  
 (ii) use
commercially reasonable efforts to file with the Commission in a timely manner all reports and other documents required of the Company under the Securities Act and the Exchange Act (at any time after it has become subject to such reporting
requirements); and 
  
 (iii) furnish to any
holder of Registrable Shares upon request (A) a written statement by the Company as to its compliance with the requirements of said Rule 144(c), and the reporting requirements of the Securities Act and the Exchange Act (at any time after it has
become subject to such reporting requirements), (B) a copy of the most recent annual or quarterly report of the Company, and (C) such other reports and documents of the Company as such holder may reasonably request to avail itself of any similar
rule or regulation of the Commission allowing it to sell any such securities without registration. 

 3.9 Limitations on Subsequent Registration Rights. From and after the date of this Agreement, the
Company shall not, without the prior written consent of the holders of a majority of the outstanding Registrable Shares, enter into any agreement with any holder or prospective holder of any securities of the Company that would either (i) grant such
holder registration rights senior to those granted to the Stockholders hereunder, or (ii) reduce in any way the number of Registrable Securities with respect to which the Stockholders have requested registration pursuant to Section 3.1 hereof.

  
 ARTICLE IV 
 RIGHT OF FIRST REFUSAL 
  
 4.1 Right of First Refusal 
  
 (a) Subject to the exceptions set forth in Section 4.2 hereof, the Company shall not issue, sell or exchange, agree to issue, sell or
exchange, or reserve or set aside for issuance, sale or exchange, (i) any shares of its Common Stock, (ii) any other equity securities of the Company, including, without limitation, shares of preferred stock, (iii) any option, warrant or other right
to subscribe for, purchase or otherwise acquire any equity securities of the Company, or (iv) any debt securities convertible into capital stock of the Company (collectively, the “Offered Securities”), unless in each
such case the Company shall have first complied with Article IV of this Agreement. The Company shall deliver to each Major Preferred Investor that holds at least 1,000,000 shares of Preferred Stock (as adjusted for subsequent stock splits, stock
dividends, combinations and other recapitalizations) (a “Major Preferred Investor”) a written notice of any proposed or intended issuance, sale or exchange of Offered Securities (the
“Offer”), which Offer shall (i) identify and describe the Offered Securities, (ii) describe the price and other terms upon which they are to be issued, sold or exchanged, and the number or amount of the Offered Securities to be
issued, sold or exchanged, (iii) identify the persons or entities, if known, to which or with which the Offered Securities are to be offered, issued, sold or exchanged, and (iv) offer to issue and sell to or exchange with such Major Preferred
Investor (A) such portion of the Offered Securities as is equal to (1) the number of Offered Securities multiplied by (2) a fraction the numerator of which is the aggregate number of shares of Common Stock issued or issuable upon conversion of the
Shares held by such Major Preferred Investor and the denominator of which is the total number of shares of Common Stock issued or issuable upon conversion of the Shares held by all Preferred Investors as a group (the “Basic
Amount”), and (B) such additional portion of the Offered Securities as such Major Preferred Investor shall indicate it will purchase or acquire should the other Major Preferred Investors subscribe for less than their Basic Amounts (the
“Undersubscription Amount”). Each Major Preferred Investor shall have the right in accordance with Paragraph (b) below to purchase or acquire, at the price and upon the other terms specified in the Offer, the number or amount of
Offered Securities described above. The Offer by its terms shall remain open and irrevocable for such 10-day period. 
  
 (b) To accept an Offer, in whole or in part, a Major Preferred Investor must deliver a written notice to the Company prior to the end of
the 10-day period of the Offer, setting forth the portion of such Major Preferred Investor’s Basic Amount that such Major Preferred 

 
Investor elects to purchase and, if such Major Preferred Investor shall elect to purchase all of its Basic Amount, the Undersubscription Amount (if any) that
such Major Preferred Investor elects to purchase (the “Notice of Acceptance”). If the Basic Amounts subscribed for by all Major Preferred Investors are less than the total Basic Amounts, then each Major Preferred Investor who has
set forth an Undersubscription Amount in its Notice of Acceptance shall be entitled to purchase, in addition to the Basic Amounts subscribed for, and on the same terms as the Basic Amounts, the Undersubscription Amount it has subscribed for;
provided, however, that should the Undersubscription Amounts subscribed for exceed the difference between the total Basic Amounts and the Basic Amounts subscribed for (the “Available Undersubscription
Amount”), each Major Preferred Investor who has subscribed for any Undersubscription Amount shall be entitled to purchase only that portion of the Available Undersubscription Amount as the Undersubscription Amount subscribed for by such
Major Preferred Investor bears to the total Undersubscription Amounts subscribed for by all Major Preferred Investors, subject to rounding by the Board of Directors to the extent it reasonably deems necessary. 
  
 (c) In the event that Notice of Acceptances are not given by
Major Preferred Investors in respect of all the Offered Securities, the Company shall have 90 days from the expiration of the 10-day period set forth in Section 4.1(a) to issue, sell or exchange all or any part of such Offered Securities as to which
a Notice of Acceptance has not been given by the Major Preferred Investors (the “Refused Securities”), but only to the offerees or purchasers described in the Offer and only upon terms and conditions (including, without limitation,
unit prices and interest rates) which are not more favorable, in the aggregate, to the acquiring person or persons or less favorable to the Company than those set forth in the Offer. 
  
 (d) In the event the Company shall propose to sell less than all of the Refused Securities (any such sale to
be in the manner and on the terms specified in Section 4.1(c)), then each Major Preferred Investor may, at its sole option and in its sole discretion, reduce the number or amount of the Offered Securities specified in its Notice of Acceptance to an
amount that shall be not less than the number or amount of the Offered Securities that the Major Preferred Investor elected to purchase pursuant to Section 4.1(b) multiplied by a fraction, (i) the numerator of which shall be the number or amount of
Offered Securities the Company actually proposes to issue, sell or exchange (including Offered Securities to be issued or sold to Major Preferred Investors pursuant to Section 4.1(b) prior to such reduction) and (ii) the denominator of which shall
be the amount of all Offered Securities. In the event that a Major Preferred Investor so elects to reduce the number or amount of Offered Securities specified in its Notice of Acceptance, the Company may not issue, sell or exchange more than the
reduced number or amount of the Offered Securities unless and until such securities have again been offered to the Major Preferred Investors in accordance with Section 4.1(a). Notwithstanding the foregoing provisions of this Section 4, the Company
shall not be required to offer or sell Offered Securities to any Major Preferred Investor who would cause the Company to be in violation of applicable federal securities laws by virtue of such offer or sale. 
  
 (e) Upon the closing of the issuance, sale or exchange of
all or less than all the Refused Securities, the Major Preferred Investors shall acquire from the Company, and the Company shall issue to the Major Preferred Investors, the number or amount of Offered Securities specified in the Notices of
Acceptance, as reduced pursuant to Section 4.1(d) if the 

 
Major Preferred Investors have so elected, upon the terms and conditions specified in the Offer. The purchase by the Major Preferred Investors of any Offered
Securities is subject in all cases to the preparation, execution and delivery by the Company and the Major Preferred Investors of a purchase agreement relating to such Offered Securities reasonably satisfactory in form and substance to the Major
Preferred Investors and the Company. 
  
 (f) Any
Offered Securities not acquired by the Major Preferred Investors or other persons in accordance with Section 4.1(c) may not be issued, sold or exchanged until they are again offered to the Major Preferred Investors under the procedures specified in
this Article. 
  
 4.2 Excluded Issuances. The rights of the
Preferred Investors under this Article IV shall not apply to: 
  
 (a) securities of the Company issued pursuant to the Series C Purchase Agreement; 
  
 (b) Common Stock issued as a stock dividend or other distribution to holders of Common Stock, Series A Preferred Stock, Series B Preferred
Stock or Series C Preferred Stock upon any subdivision or combination of shares of Common Stock, Series A Preferred Stock, Series B Preferred Stock or Series C Preferred Stock, or in the event of any reclassification or reorganization affecting the
Company’s capital stock; 
  
 (c) the
issuance of any shares of Common Stock upon conversion or exercise of outstanding convertible or exercisable securities; 
  
 (d) securities issued with the approval of the Board of Directors of the Company and the holders of more than 50% of the Series C
Preferred Stock; 
  
 (e) up to 9,737,434 shares
of Common Stock, either issued in the form of restricted stock awards or options exercisable for Common Stock (subject to appropriate adjustment for any stock splits, stock dividends, combinations and other similar recapitalizations affecting such
shares), issued or issuable to officers, directors, consultants and employees of the Company or any subsidiary pursuant to the Amended and Restated 2000 Stock Option Plan (or in exchange for any stock options issued pursuant to the Amended and
Restated 2000 Stock Option Plan) or any plan, agreement or arrangement approved by the Board of Directors of the Company; 
  
 (f) securities issued solely in consideration for the acquisition (whether by merger, consolidation, sale of assets or otherwise) by the
Company or any of its subsidiaries of all or substantially all of the stock or assets of any other entity provided that such agreement or arrangement is approved by the Board of Directors of the Company; 
  
 (g) 1,498,300 shares of Common Stock in the aggregate issued
pursuant to the Common Stock Purchase Agreement; 
  

 (h) the issuance of securities pursuant to the conversion or exercise of outstanding
convertible or exercisable securities; or 
  
 (i)
shares of Common Stock sold by the Company in an underwritten public offering pursuant to an effective registration statement under the Securities Act. 
  
 4.3 Waiver. The observance of any term of this Article IV may be waived (either generally or in a particular instance and either retroactively or
prospectively) with the written consent of the Company and the holders of 50% of the Registrable Securities held by the Major Preferred Investors. Any waiver effected in accordance with this paragraph shall be binding upon each holder of any
Registrable Securities, each future holder of all such Registrable Securities, and the Company. 
  
 ARTICLE V 
 COVENANTS 
  

5.1 Vesting of Stock Options and Restricted Stock. For so long as any shares of Series A Preferred Stock, Series B Preferred Stock or Series C
Preferred Stock remain outstanding, and except as otherwise approved by the Board of Directors of the Company, all options or shares of restricted Common Stock issued after the date hereof to directors, officers, consultants or employees of the
Company shall vest at the rate of (i) 25% upon the one year anniversary of the date of issuance and (ii) the remaining 75%, monthly, over the three year period following the anniversary of the date of issuance; provided, however, that such vesting
may be modified so that vesting dates occur uniformly on the first or last day of any month or fiscal quarter. 
  
 5.2 Company Funds May Not Be Used To Reimburse Tax Liabilities. To the extent an employee, director or consultant has failed to timely file a
Section 83(b) election, the Company shall not use any Company funds or provide any other means of financial assistance to reimburse or otherwise assist the employee, director or consultant with the payment of tax liabilities or other obligations
owing from the failure to timely file a Section 83(b) election except as approved by the Board of Directors of the Company. 
  
 5.3 Other Covenants. The Company hereby covenants as follows: 
  
 (a) The Company shall file a Form D with respect to the sale and issuance of the Series C Preferred Stock
with the Commission within 15 days of the Initial Closing (as defined in the Series C Purchase Agreement). 
  
 (b) The Company shall reimburse its directors and an additional representative of MPM and Frazier, respectively, authorized by the Company
to attend meetings of the Company’s Board of Directors for reasonable travel and related expenses incurred for attending Board meetings of the Company. 
  
 (c) The Company shall require all employees and consultants with access to confidential information of the Company to execute and deliver
a proprietary information and 

 
inventions agreement in substantially the form approved by the Company’s Board of Directors (including the approval of the director nominated by the
holders of the Series C Preferred Stock, voting together as a single class or the “Series C Director”). 
  
 (d) Subject to approval of the Board of Directors of the Company, the Company shall obtain and maintain in full force and effect term life
insurance on the lives of key-employees of the Company as determined by the Board of Directors, which determination shall include the vote of the Series C Director, with proceeds payable to the Company until such time as the Board of Directors
determines that such insurance should be discontinued. 
  
 (e) The Company shall use reasonable effort to maintain director and officer liability insurance with terms acceptable to the Board of Directors of the Company. 
  
 (f) The Company shall use reasonable effort to maintain a compensation committee of the Company’s Board
of Directors for purposes of determining the executive’s salaries and bonuses, which committee shall include the Series C Director, who shall initially be Nicholas Simon and two outside directors who shall not be then providing services to the
Company as an employee. 
  
 (g) The Company shall
not make any loan to any director or executive officer which would be in violation of the Sarbanes-Oxley Act at the time of the Company’s sale of shares of Common Stock in a firm commitment underwritten public offering to be listed on the
Nasdaq National Market or the New York Stock Exchange pursuant to a Registration Statement. 
  
 (h) The Company shall use its best efforts to secure signature pages to the Second Amended and Restated Right of First Refusal and Co-Sale
Agreement in the form attached hereto as Exhibit B (the “Series C Right of First Refusal and Co-Sale Agreement”) from the persons and entities listed on Exhibit C (the “Signature Pages”) as soon as
practicable following the Initial Closing (as defined in the Series C Purchase Agreement). Immediately upon its receipt of all of the Signature Pages, the Company shall execute the Series C Right of First Refusal Agreement by and among the Company,
the Founders, and the Investors (each as defined therein) dated as of such date. In the event the Company fails to secure all of the Signature Pages within thirty (30) days of the Initial Closing, immediately upon its receipt of written instruction
from the holders representing a majority of the Series C Preferred Stock, the Company shall enter into the Series C Right of First Refusal and Co-Sale Agreement by and among the Company, the Founders, and all of the Investors except those from whom
they have not yet received a Signature Page dated as of such date. 

 ARTICLE VI 
 GENERAL 
  
 6.1
Termination. Article III of this Agreement shall terminate in its entirety upon the five-year anniversary of the closing of a Qualified Initial Public Offering. Articles IV and V of this Agreement shall terminate in their entirety upon the
earlier of a completion of (a) a Liquidation Event, or (b) the closing of a Qualified Initial Public Offering, or (c) the redemption of all Shares. 
  
 6.2 Transfer of Rights. 
  
 (a) This Agreement, and the rights and obligations of Columbia, the Founders and the Preferred Investors with regard to the number of
Shares held hereunder, may be assigned by Columbia, a Founder, or a Preferred Investor, as the case may be to any person or entity to which (i) at least 75,000 shares (or all shares then held by such party if less than 75,000 shares) of capital
stock of the Company, as adjusted for stock splits, stock dividends, recapitalizations and similar events, are transferred by Columbia, a Founder or a Preferred Investor, as the case may be or (ii) at least 75,000 shares (or all shares then held by
such party if less than 75,000 shares) of capital stock of the Company, as adjusted for stock splits, stock dividends, recapitalizations and similar events are held by such transferree (including this proposed transfer), and such transferee shall be
deemed “Columbia”, a “Founder” or a “Preferred Investor, as the case may be for purposes of this Agreement; provided that the transferee provides written notice of such assignment to the Company and agrees to be bound
by the terms and conditions set forth herein. 
  
 (b) Notwithstanding the foregoing, this Agreement, and the rights and obligations of a Preferred Investor hereunder, may be assigned by a Preferred Investor without regard to the number of Shares transferred or held by the assignee to any
affiliate of such Preferred Investor, and such transferee shall be deemed a “Preferred Investor,” as the case may be, for purposes of this agreement; provided that the transferee provides written notice of such assignment to the
Company and agrees to be bound by the terms and conditions set forth herein. 
  
 6.3 Severability. The provisions of this Agreement are severable, so that the invalidity or unenforceability of any provision of this Agreement shall not affect the validity or enforceability of any other term
or provision of this Agreement, which shall remain in full force and effect. 
  
 6.4 Specific Performance. In addition to any and all other remedies that may be available at law in the event of any breach of this Agreement, the Preferred Investors and the Founders shall be entitled to
specific performance of the agreements and obligations of the other parties hereunder and to such other injunctive or other equitable relief as may be granted by a court of competent jurisdiction. 
  
 6.5 Governing Law. This Agreement shall be governed by, and construed
and enforced in accordance with, the laws of the State of California (without reference to the conflicts of law provisions thereof). 

 6.6 Notices. All notices, requests, consents, and other communications under this Agreement shall
be in writing and shall be delivered by hand, sent via a reputable nationwide overnight courier service or mailed by first class certified or registered mail, return receipt requested, postage prepaid: 
  
 (a) in the case of a Preferred Investor, to him, her or it
at the last residence or business address shown in the records of the Company, provided that if such notice is to be sent to any holder of Series C Preferred Stock, a copy shall also be sent to: 
  
 J. Casey McGlynn, Esq. 
 Wilson Sonsini Goodrich & Rosati 
 650 Page Mill Road 
 Palo Alto, CA 94304-1050 
 Fax: (650) 493-6811 
  
 (b) in the case of the Company, to the Company at: 
  
 CoTherix, Inc. 
 1301 Shoreway Road, Suite 320 
 Belmont, California 94002 
 Attention: President 
  
 with a copy to: 
  
 Bennett L. Yee, Esq. 
 Gunderson Dettmer Stough Villeneuve Franklin & Hachigian, LLP 
 155 Constitution Drive 
 Menlo Park, California 94025 
 Fax: 650-321-2800 
  
 (c) in the case of a Founder, at his address as set forth on the signature pages hereto, or at such other address or addresses as may have been furnished by such Founder to the Company and the Preferred Investor; or 
  
 (d) in the case of Columbia, to Columbia at: 
  
 Executive Director 
 Columbia Innovation Enterprise 
 Columbia University 
 Engineering Terrace, Suite 363 
 500 West 120 Street, Mail Code 2206 
 New York, New York 10027 
  
 with a copy to: 

 General Counsel 
 Columbia University 
 412 Low Memorial Library 
 535 West 116 Street, Mail Code 4308 
 New York,
New York 10027. 
  
 Any notice or other communication pursuant to
this Agreement shall be deemed to have been duly given or made and to have become effective (i) when delivered in hand to the party to which it was directed, (ii) if sent by telex, telecopier, facsimile machine or telegraph and properly addressed in
accordance with the foregoing provisions of this Section 6.6, when received by the addressee, so long as proof of transmission is available, (iii) if sent by commercial courier guaranteeing next business day delivery, on the business day following
the date of delivery to such courier, or (iv) if sent by first-class mail, postage prepaid, and properly addressed in accordance with the foregoing provisions of this Section 6.6, upon the earlier of receipt by the addressee, or the third business
day following the day of dispatch thereof. 
  
 6.7 Complete
Agreement; Amendments. 
  
 (a) This Agreement
contains the entire agreement of the parties hereto with respect to the subject matter hereof. From and after the delivery of this Agreement, the Prior Investor Rights Agreement shall be deemed to be terminated and superceded in all respects. By
their execution of this Agreement, all the parties hereto who are parties to the Prior Investor Rights Agreement consent to the termination of the Prior Investor Rights Agreement and acknowledge and agree that they have no remaining rights or
obligations under such Prior Investor Rights Agreement other than those which have accrued or vested prior to the effective time of this Agreement. 
  
 (b) This Agreement may be amended at any time by a written instrument signed by the Company, Preferred Investors holding a majority of the
shares of Common Stock issued or issuable upon conversion of the Registrable Shares held by them, and, with respect to any amendment to Section 3.2 of Article III, Founders holding a majority, by voting power, of the shares of capital stock of the
Company held by Founders then employed by the Company. Notwithstanding the foregoing, (x) no amendment that adversely affects any of the specific rights of Columbia under this Agreement shall be effective without the prior written consent of
Columbia, and (y) no amendment to Section 5.3 of this Agreement shall be effective without the prior written consent of MPM. No waivers of or exceptions to any term, condition or provision of this Agreement, in any one or more instances, shall be
deemed to be, or construed as, a further or continuing waiver of any such term, condition or provision. Notwithstanding the foregoing, purchasers of shares of the Company’s Series C Preferred Stock pursuant to the Series C Purchase Agreement or
an addendum thereto after the date of the Purchase Agreement may be subsequently added as a party to this Agreement and shall be bound by and entitled to the terms, benefits and conditions herein by the execution of this Agreement on a signature
page to this Agreement. 

 6.8 Pronouns. Whenever the content may require, any pronouns used in this Agreement shall include
the corresponding masculine, feminine or neuter forms, and the singular form of nouns and pronouns shall include the plural, and vice versa. 
  
 6.9 Counterparts. This Agreement may be executed in any number of counterparts, each of which shall be deemed to be an original, and all of which
together shall constitute one Agreement binding on all the parties hereto. 
  
 6.10 Captions. Captions of sections have been added only for convenience and shall not be deemed to be a part of this Agreement. 
  
 6.11 Aggregation of Stock. All Registrable Shares held or acquired by affiliated entities (including affiliated
venture capital funds) or Persons shall be aggregated together for the purpose of determining the availability of any rights under this Agreement. 
  
 6.12 Telecopy Execution and Delivery. A facsimile, telecopy or other reproduction of this Agreement may be executed by one or more parties hereto
and delivered by such party by facsimile or any similar electronic transmission device pursuant to which the signature of or on behalf of such party can be seen. Such execution and delivery shall be considered valid, binding and effective for all
purposes. At the request of any party hereto, all parties hereto agree to execute and deliver an original of this Agreement as well as any facsimile, telecopy or other reproduction hereof. 
  
 [remainder of page intentionally left blank] 

 SCHEDULE A 
  

			
	 Sofinnova Venture Partners V, LP
	 	MPM Asset Management Investors 2003 BVIII LLC
		
	 Sofinnova Venture Affiliates V, LP
	 	Thomas Weisel Healthcare Venture Partners, L.P.
		
	 Sofinnova Venture Principals V, LP
	 	Frazier Healthcare IV, L.P.
		
	 Sofinnova Capital IV FCPR
	 	Frazier Affiliates IV, L.P.
		
	 Alta California Partners III, L.P.
	 	Alta BioPharma Partners III, L.P.
		
	 Alta Embarcadero Partners III, LLC
	 	Alta BioPharma Partners III GmbH & Co. Beteiligungs KS
		
	 Spray Venture Fund, L.P.
	 	Alta Embarcadero BioPharma Partners III, LLC
		
	 Walnut Street Partners, LLC
	 	 
		
	 Biotechnology Development Fund II, L.P.
	 	 
		
	 Stephen Bochner
	 	 
		
	 OCI, Ltd.
	 	 
		
	 James W. Larrick
	 	 
		
	 Allan W. May Revocable Trust Dtd 5/14/91
	 	 
		
	 N. Reifart, Prof. MD
	 	 
		
	 G & H Partners
	 	 
		
	 Scott Harkonen
	 	 
		
	 MPM BioVentures III, L.P.
	 	 
		
	 MPM Bioventures III-QP, L.P.
	 	 
		
	 MPM Bioventures III Parallel Fund, L.P.
	 	 
		
	 MPM Bioventures III GMBH & Co. Beteiligungs Kg
	 	 

 SCHEDULE B 
  

Donald Santel 
  
 Dr. Jerome Cantor 
  
 Dr. Gerard Turino 
  
 The Trustees of Columbia University
in the City of New York 

 EXHIBIT A 
  
 Instrument of Adherence 
  
 Reference is made to that certain Second Amended and Restated Investors Rights Agreement, dated as of
                    , 2003, a copy of which is attached hereto (as amended and in effect from time to time, the “Investor Rights
Agreement”), among COTHERIX, INC., a Delaware corporation (the “Company”), the Founders, the Preferred Investors and the others party thereto. Capitalized terms used herein without definition shall have the respective
meanings ascribed thereto in the Investors Rights Agreement. 
  
 The undersigned,                     , in order to become the owner or holder of
             shares (the “Acquired Shares”) of Common Stock of the Company (assuming the conversion of all such shares that are convertible into Common Stock),
hereby agrees that, from and after the date hereof, (i) the undersigned has become a Preferred Investor party to the Investors Rights Agreement and is entitled to all of the benefits under and is subject to all of the obligations, restrictions and
limitations set forth in the Investor Rights Agreement that are applicable to the Preferred Investors and (ii) all of the Acquired Shares are entitled to all of the benefits and are subject to all of the obligations, restrictions, limitations,
provisions and conditions, under the Investor Rights Agreement that are applicable to the Shares held by the Preferred Investors. This Instrument of Adherence shall take effect and shall become a part of the Investors Rights Agreement immediately
upon execution. 
  
 Executed as of the date set forth below under
the domestic substantive laws of the State of California without giving effect to any choice or conflict of law provision or rule that would cause the application of the domestic substantive laws of any other state. 
  

			
	 Signature: 

	
	 Address: 

	
	  

	
	  

	
	 Date:  

  
 Acknowledged and Accepted:

  
 COTHERIX, INC. 
  

			
		
	By:	 	 
	 	 	

	 	 	 Name:
 Title:Standard Lease between F & S Properties, LLC and Registrant dated 12/17/03.

 EXHIBIT 10.8 
  
 STANDARD LEASE AGREEMENT 
  
  
  
 by and between 
  
  
 F & S PROPERTIES, LLC 
 (“Lessor”) 
  
  
 and 
  
  
 COTHERIX, INC. 
 (“Lessee”)

 STANDARD LEASE 
  
 TABLE OF CONTENTS 
  

			
	 1.
	  	 BASIC LEASE TERMS

	 2.
	  	 PREMISES AND COMMON AREAS

	 3.
	  	 TERM

	 4.
	  	 POSSESSION

	 5.
	  	 RENT

	 6.
	  	 OPERATING EXPENSES

	 7.
	  	 SECURITY DEPOSIT

	 8.
	  	 USE

	 9.
	  	 NOTICES

	 10.
	  	 BROKERS

	 11.
	  	 SURRENDER; HOLDING OVER

	 12.
	  	 TAXES ON LESSEE’S PROPERTY

	 13.
	  	 ALTERATIONS

	 14.
	  	 REPAIRS

	 15.
	  	 LIENS

	 16.
	  	 ENTRY BY LESSOR

	 17.
	  	 UTILITIES AND SERVICES

	 18.
	  	 ASSUMPTION OF RISK AND INDEMNIFICATION

	 19.
	  	 INSURANCE

	 20.
	  	 DAMAGE OR DESTRUCTION

	 21.
	  	 EMINENT DOMAIN

	 22.
	  	 DEFAULTS AND REMEDIES

	 23.
	  	 LESSOR’S DEFAULT

	 24.
	  	 ASSIGNMENT AND SUBLETTING

	 25.
	  	 SUBORDINATION

	 26.
	  	 ESTOPPEL CERTIFICATE

	 27.
	  	 BUILDING PLANNING

	 28.
	  	 RULES AND REGULATIONS

	 29.
	  	 MODIFICATION AND CURE RIGHTS OF LESSOR’S MORTGAGEES AND LESSORS

	 30.
	  	 DEFINITION OF LESSOR

	 31.
	  	 WAIVER

	 32.
	  	 PARKING

	 33.
	  	 FORCE MAJEURE

	 34.
	  	 SIGNS

	 35.
	  	 LIMITATION ON LIABILITY

	 36.
	  	 FINANCIAL STATEMENTS

	 37.
	  	 QUIET ENJOYMENT

	 38.
	  	 MISCELLANEOUS

	 39.
	  	 EXECUTION OF LEASE

  
 EXHIBITS: 
  

					
	 	  	 A-I
	  	 FLOOR PLAN

	 	  	 A-II
	  	 SITE PLAN

	 	  	 B
	  	 ADJUSTMENTS TO MONTHLY BASE RENT

	 	  	 C
	  	 DESCRIPTION OF LESSORS WORK

	 	  	 D
	  	 LESSEE’S INSURANCE REQUIREMENTS

	 	  	 E
	  	 DEFINITION OF OPERATING EXPENSES

	 	  	 F
	  	 STANDARDS FOR UTILITIES AND SERVICES

	 	  	 G
	  	 ESTOPPEL CERTIFICATE

	 	  	 H
	  	 RULES AND REGULATIONS

	 	  	 I
	  	 HAZARDOUS MATERIALS DISCLOSURE CERTIFICATE

  

 - 2 - 

 STANDARD LEASE 
  
 This STANDARD LEASE (“Lease”) is entered into as of December 17, 2003, by and between F & S PROPERTIES,
LLC, California Limited Liability Company (“Lessor”), and COTHERIX, INC., a Delaware corporation. (“Lessee”). 
  

	1.	BASIC LEASE TERMS: For purposes of this Lease, the following terms have the following definitions and meanings: 

  

	 	(a)	Lessor’s Address (For Notices): 

  
 F & S PROPERTIES, LLC 
 c/o Foster
Enterprises 
 250A Twin Dolphin Drive 
 Redwood City, CA 94065-1402 
  
 or such other place as
Lessor may from time to time designate by notice to Lessee. 
  

	 	(b)	Lessee’s Address (Premises): 

  
 CoTherix, Inc. 
 1301 Shoreway Road, Suite 320

 Belmont, CA 94002 
  
 Lessee’s Address (For Notices): PLEASE PROVIDE / CONFIRM BELOW 
  
 Same As Above 
  

	 	(c)	Premises: Suite 320 of the building located at 1301 Shoreway Road as shown on Exhibit “A-I” (the “Premises”), which Premises contains approximately 5,470
rentable square feet. The Premises is located within the building commonly known as Belmont Shores Office Building (“Building”) containing approximately 142,601 rentable square feet shown on Exhibit “A-II” in the City of Belmont
(“City”), County of San Mateo (“County”), State of California (“State”). 

  

	 	(d)	Lessee’s Percentage of Operating Expenses and Real Property: N/A 

  

	 	(e)	Term: Two (2) Months 

  

	 	(f)	Commencement Date: February 1, 2004 

  

	 	(g)	Expiration Date: March 31, 2004 

  

	 	(h)	Initial Monthly Base Rent: $10,940.00 ($2.00/s.f.). Rent is due on the first day of the month and delinquent on the sixth day. Late payments will be subject to interest and a
late charge as provided in Subparagraph 22(g) below. 

  

	 	(i)	Base Year: N/A 

  

	 	(j)	Security Deposit: $10,940.00 due upon execution of the Lease. 

  

	 	(k)	Permitted Use: A general business office and administrative uses consistent with the office nature of the facility, and no other use without the express written consent of
Lessor, which consent Lessor may withhold in its sole and absolute discretion. 

  

	 	(l)	Parking: Nineteen (19) parking spaces (3.5/1,000), subject to the terms and conditions of Paragraph 32 below and the Rules and Regulations regarding parking contained in
Exhibit “H”. 

  

	 	(m)	Brokers: N/A 

  

	 	(n)	Guarantor(s): N/A 

  

	 	(o)	Interest Rate: The greater of ten percent (10%) per annum or two (2) percentage points in excess of the prime lending or reference rate of Wells Fargo Bank N.A. or any
successor bank in effect on the twenty-fifth (25th) day of the calendar month immediately prior to the event giving rise to the Interest Rate imposition; provided, however, the Interest Rate will no event exceed the maximum interest rate permitted
to be charged by applicable law. 

  

	 	(p)	Exhibits: A through I inclusive, which Exhibits are attached to this Lease and incorporated herein by this reference. 

  
 This Paragraph 1 represents a summary of the basic terms and definitions of
this Lease. In the event of any inconsistency between the terms contained in this Paragraph 1 and any specific provision of this Lease, the terms of the more specific provision shall prevail. 
  

 - 3 - 

	2.	PREMISES AND COMMON AREAS 

  

	 	(a)	Premises: Lessor hereby leases to Lessee and Lessee hereby leases from Lessor the Premises upon and subject to the terms, covenants and conditions contained in this Lease to
be performed by each party. 

  

	 	(b)	Lessee’s Use of Common Areas: During the Term of the Lease, Lessee shall have the nonexclusive right to use in common with all other occupants of the Building, the
following common areas of the Building (collectively, the “Common Areas”): the parking facilities of the Building which serve the Building, loading and unloading areas, trash areas, roadways, sidewalks, walkway, parkways, driveway,
landscaped areas, conference room, exercise room, tennis court and similar areas and facilities situated within the Building and appurtenant to the Building which are not reserved for the exclusive use of any Building occupants.

  

	 	(c)	Lessor’s Reservation of Rights: Provided Lessee’s use of and access to the Premises is not interfered with in an unreasonable manner, Lessor reserves for itself and
for all other owner(s) and operator(s) of the Common Areas and the balance of the Building, the right from time to time to: (i) install, use, maintain, repair, replace and relocate pipes, ducts, conduits, wires and appurtenant meters and equipment
above the ceiling surfaces, below the floor surfaces and within the walls of the Building; (ii) make changes to the design and layout of the Building, including, without limitation, changes to buildings, driveways, entrances, loading and unloading
areas, direction of traffic, landscaped areas and walkways, parking spaces and parking areas; and (iii) use or close temporarily the Common Areas, and/or other portion of the Building while engaged in making improvements, repairs or alterations to
the Building, the Building, or any portion thereof. 

  

	3.	TERM: The term of this Lease (“Term”) will be for the period designated in Subparagraph 1(e), commencing on the “Commencement Date”, and ending on the
Expiration Date designated in Subparagraph 1 (g) (the “Expiration Date”). 

  

	4.	POSSESSION: 

  

	 	(a)	Delivery of Possession: Lessee is in possession of the Premises by virtue of a sublease by and between Oracle and Lessee, which will expire on January 31, 2004.

  

	 	(b)	Condition of Premises: Unless Lessee gives Lessor written notice within ten (10) business days of taking possession of the Premises, Lessee will be deemed to have accepted
the Premises in its “as-is” condition on the Commencement Date. Lessee acknowledges that neither Lessor nor any agent of Lessor has made any representation or warranty with respect to the Premises, the Building, the Building or any
portions thereof or with respect to the suitability of same for the conduct of Lessee’s business and Lessee further acknowledges that Lessor will have no obligation to construct or complete any additional buildings or improvements within the
Building. Lessor makes no representation or warranty regarding the installation or ownership or intrabuilding network telephone or telecommunication cabling within the Building. Lessor acknowledges and consents to Lessee’s use of the furniture
in the Premises owned by Oracle. Lessor consents to entry by Oracle on or before the Expiration Date to remove such furniture. 

  

	5.	RENT: 

  

	 	(a)	Monthly Base Rent: Lessee agrees to pay Lessor the Monthly Base Rent for the Premises (subject to adjustment as hereinafter provided) in advance on the first day of the Term
without prior notice or demand. All rent must be paid to Lessor, without any deduction or off-set unless permitted by law, in lawful money of the United States of America, at the address designated by Lessor or to such other person or at such other
place as Lessor may from time to time designate in writing. 

  

	 	(b)	Additional Rent: All amounts and charges other than Monthly Base Rent to be paid by Lessee hereunder, will be considered additional rent for purposes of this Lease, and the
word “rent” as used in this Lease will include all such additional rent unless the context specifically or clearly implies that only Monthly Base Rent in intended. 

  

	 	(c)	Late Payments: Late payments of Monthly Base Rent and/or item of additional rent will be subject to interest and a late charge as provided in Subparagraph 22(g) below.

  

	6.	OPERATING EXPENSES AND REAL PROPERTY TAXES: 

  

	 	(a)	Operating Expenses and Real Property Taxes: Lessee will not be obligated for any payments for Operating Expenses or Real Property Taxes. The Monthly Base Rent includes full
payment of all such obligations. 

  

	7.	 SECURITY DEPOSIT: Concurrently with Lessee’s execution of this Lease, Lessee will deposit with Lessor the Security Deposit designated in Subparagraph
1(j). The Security Deposit will be held by Lessor as security for the full and faithful performance by Lessee of all of the terms, covenants, and conditions of this Lease to be kept and performed by Lessee during the Term hereof. The Security
Deposit is not, and may not be construed by Lessee to constitute, rent for the last month or any portion thereof. If Lessee defaults with respect to any provisions of this Lease including, but not limited to, the provisions relating to the payment
of rent or additional rent, Lessor may (but will not be required to) use, apply or retain all or any part of the Security Deposit for the payment of any rent or any other sum in default, or for the payment of any other amount which Lessor may spend
by reason of Lessee’s default or to compensate Lessor for any loss or damage which Lessee is 

  

 - 4 - 

	 	 
responsible for. If any portion of the Security Deposit is so used or applied, Lessee agrees, within thirty (30) days after Lessor’s written demand
therefor, to pay Lessor an amount sufficient to restore the Security Deposit to its original amount; Lessee’s failure to do so shall constitute a default under this Lease. Lessor is not required to keep Lessee’s Security Deposit separate
from its general funds, and Lessee is not entitled to interest on such Security Deposit. 

  

	8.	USE: 

  

	 	(a)	Lessee’s Use of the Premises: The Premises may be used for the use or uses set forth in Subparagraph 1(k) only, and Lessee will not use or permit the Premises to be used
for any other purpose without the prior written consent of Lessor, which consent Lessor may withhold in its sole and absolute discretion. Lessee shall have the exclusive right to use the Premises pursuant to the foregoing provision. Nothing in this
Lease will be deemed to give Lessee any exclusive right to such use in the Building. 

  

	 	(b)	Compliance: At Lessee’s sole cost and expense, Lessee agrees to procure, maintain and hold available for Lessor’s inspection, all governmental licenses and permits
required for the proper and lawful conduct of Lessee’s business from the Premises, if any. Lessee agrees not to use, alter or occupy the Premises or allow the Premises to be used, altered and occupied in violation of, and Lessee, at its sole
cost and expense, agrees to use and occupy the Premises, and cause the Premises to be used and occupied, in compliance with: (i) any and all laws, statutes, zoning restrictions, ordinances, rules, regulations, orders and rulings now or hereafter in
force and any requirements of any insurer, insurance authority or duly constituted public authority having jurisdiction over the Premises, the Building or the Building now or hereafter in force, (ii) the requirements of the Board of Fire
Underwriters and any other similar body, (iii) any Certificate of Occupancy issued for the Building, and (iv) any recorded covenants, conditions and restrictions and similar regulatory agreements, if any, which affect the use, occupation or
alteration of the Premises, the Building and/or the Building. Lessee agrees to comply with the Rules and Regulations referenced in Paragraph 28 below. Lessee agrees not to do or permit anything to be done in or about the Premises or the common areas
which will in any manner obstruct or interfere with the rights or other tenants or occupants of the Building, or injure or unreasonably annoy them, or use or allow the Premises or the common areas to be used for any unlawful or unreasonably
objectionable purpose. Unless otherwise permitted by this Lease, Lessee agrees not to place or store any articles or materials outside of the Premises without the prior written consent of Lessor or to cause, maintain or permit any nuisance or waste
in, on, under or about the Premises or elsewhere within the Building. Lessee shall not use or allow the Premises to be used for lodging, bathing or the washing of clothes without the prior written consent of Lessor. 

  

	 	(c)	 Hazardous Materials: Except for ordinary and general office supplies, including but not limited to copier toner, liquid paper, glue, ink and common household
cleaning materials (some or all of which may constitute “Hazardous Materials” as defined in this Lease), Lessee agrees not to cause or permit any Hazardous Materials to be brought upon, stored, used, handled, generated, released or
disposed of, on, in, under or about the Premises, the Building, the Common Areas or any other portion of the Building by Lessee, its agents, employees, subtenants, assignees, licensees, contractors or invitees (collectively, “Lessee’s
Parties”), without the prior written consent of Lessor, which consent Lessor may withhold in its sole and absolute discretion. Concurrently with the execution of this Lease, Lessee agrees to complete and deliver to Lessor an Environmental
Questionnaire in the form of Exhibit ‘I’ attached hereto. Upon the expiration or earlier termination of this Lease, Lessee agrees to promptly remove from the Premises, the Building and the Building, at its sole cost and expense, any and
all Hazardous Materials, including any equipment or systems containing Hazardous Materials that are installed, brought upon, stored, used, generated or released upon, in, under or about the Premises, the Building and/or the Building or any portion
thereof by Lessee or any of Lessee’s Parties. To the fullest extent permitted by law, Lessee agrees to promptly indemnify, protect, defend and hold harmless Lessor and Lessor’s partners, officers, directors, employees, agents, successors
and assigns (collectively, “Lessor Indemnified Parties”) from and against any and all claims, damages, judgments, suits, causes of action, losses, liabilities, penalties, fines, expenses and costs (including, without limitation, clean-up,
removal, remediation and restoration costs, sums paid in settlement of claims, reasonable attorney’s fees, reasonable consultant and expert fees and court costs) which arise or result from the presence of Hazardous Materials on, in, under or
about the Premises, the Building or any other portion of the Building and which are caused or permitted by Lessee or any of Lessee’s Parties. Lessee agrees to promptly notify Lessor of any release of Hazardous Materials in the Premises, the
Building or any other portion of the Building which Lessee becomes aware of during the Term of this Lease, whether caused by Lessee or any other persons or entities. In the event of any release of Hazardous Materials caused or permitted by Lessee or
any of Lessee’s Parties, Lessor shall have the right, but not the obligation, to cause Lessee to immediately take all steps Lessor deems necessary or appropriate to remediate such release and prevent any similar future release to the
satisfaction of Lessor and Lessor’s mortgagee(s). At all times during the Term of this Lease, Lessor will have the right, but not the obligation, to enter upon the Premises to reasonably inspect, investigate, sample and/or monitor the Premises
to determine if Lessee is in compliance with the terms of this Lease regarding Hazardous Materials. Lessor shall make reasonable efforts to schedule such any such entrance so that it shall not impose an unreasonable burden upon Lessee. Lessor shall
be responsible to Lessee for any costs that Lessee may incur due to an unreasonable entrance upon the Premises. As used in this Lease, the term “Hazardous Materials” shall mean and include any substances or wastes now or hereafter
designated as hazardous or toxic material under any law, statute, ordinance, rule, regulation, order or ruling of any agency of the State, the United States Government or any local governmental authority, including, without 

  

 - 5 - 

	 	 
limitation, asbestos, petroleum, petroleum hydrocarbons and petroleum based products, urea formaldehyde foam insulation, polychlorinated biphenyls
(“PCBs”) and freon and other chlorofluorocarbons. The provisions of this Subparagraph 8(c) will survive the expiration or earlier termination of this Lease. 

  

	 	(d)	Refuse and Sewage: Lessee agrees not to keep any trash, garbage, waste or other refuse on the Premises except in reasonably sanitary containers and agrees to regularly and
frequently remove same from the Premises. Lessee shall keep all containers or other equipment used for storage of such materials in a reasonably clean and sanitary condition. Lessee shall properly dispose of all sanitary sewage and shall not use the
sewage disposal system for the disposal of anything except sanitary sewage. Lessee shall keep sewage disposal system free of all obstructions and in good operating condition. If the volume of Lessee’s trash becomes excessive in Lessor’s
judgment, Lessor shall have the right to charge Lessee a reasonable amount for additional trash disposal services or to require that Lessee contract directly for additional trash disposal services at Lessee’s sole cost and expense.

  

	9.	NOTICES: Any notice required or permitted to be given hereunder must be in writing and may be given by personal delivery (including delivery by overnight courier or an
express mailing service) or by mail, if sent by registered or certified mail. Notices to Lessee shall be sufficient if delivered to Lessee at the Premises and notices to Lessor shall be sufficient if delivered to Lessor at the address designated in
Subparagraph 1(a). Either party may specify a different address for notice purposes by written notice to the other, except that the Lessor may in any event use the Premises as Lessee’s address for notice purposes if Lessee does not notify
Lessor of a valid address for notices. 

  

	10.	BROKERS: (No brokers involved) The parties acknowledge that the only broker(s) involved in the consummation of this Lease are stated in Subparagraph 1(m). Lessor and
Lessee each agree to promptly indemnify, protect, defend and hold harmless the other from and against any and all claims, damages, judgments, suits, causes of action, losses, liabilities, penalties, fines, expenses and costs (including reasonable
attorney’s fees and court costs) resulting from any breach by the indemnifying party of the foregoing representation, including, without limitation, any claims that may be asserted by any broker, agent or finder undisclosed by the indemnifying
party. The foregoing mutual indemnity shall survive the expiration or earlier termination of this Lease. Lessee agrees that Lessor will not recognize or compensate any third party broker with regards to any renewals and/or expansions unless such
renewal or expansion rights are included within this Lease at the time of execution by the parties and in Lessor’s commission agreement with the broker(s) specified in Subparagraph 1(n). 

  

	11.	SURRENDER; HOLDING OVER: 

  

	 	(a)	Surrender: The voluntary or other surrender of this Lease by Lessee, or a mutual cancellation thereof, shall not constitute a merger, and shall, at the option of Lessor,
operate as an assignment to Lessor of any or all subleases or subtenancies. Upon the expiration or earlier termination of this Lease, Lessee agrees to peaceably surrender the Premises to Lessor broom clean and otherwise in the same condition as
received, ordinary wear and tear and casualty damage excepted, with all of Lessee’s personal property, fixtures, and alterations removed from the Premises and all damage caused by such removal repaired. The delivery of keys to any employee of
Lessor or to Lessor’s agent or any employee thereof alone will not be sufficient to constitute a termination of this Lease or a surrender of the Premises. 

  

	 	(b)	Holding Over: If Lessee holds over after the expiration or earlier termination of the Term, Lessor may, at its option, treat Lessee as a tenant as sufferance only, and
such continued occupancy by Lessee shall be subject to all of the terms, covenants and conditions of this Lease, so far as applicable, including the payment of Operating Expenses, except that the Monthly Base Rent for any month or partial month
during which Lessee holds over shall be equal to one hundred fifty percent (150%) of Monthly Base Rent in effect under this Lease immediately prior to such holdover. Acceptance by Lessor of rent after such expiration or earlier termination will not
result in a renewal of this Lease. If Lessee fails to surrender the Premises upon the expiration of this Lease in accordance with the terms of this Paragraph 11 despite demand to do so by Lessor, Lessee agrees to promptly indemnity, protect, defend
and hold Lessor harmless from all claims, damages, judgments, suits, causes of action, losses, liabilities, penalties, finds, expenses and costs (including attorneys’ fees and costs), including, without limitation, costs and expenses incurred
by Lessor in returning the Premises to the condition in which Lessee was to surrender it and claims made by any succeeding tenant founded on or resulting from Lessee’s failure to surrender the Premises. The provisions of this Subparagraph 11(b)
will survive the expiration or earlier termination of this Lease. 

  

	12.	TAXES ON LESSEE’S PROPERTY: Lessee agrees to pay before delinquency, all taxes and assessments (real and personal) levied against Lessee’s business operations or
any personal property, improvements, alterations, trade fixtures or merchandise placed by Lessee in or about the Premises. 

  

	13.	ALTERATIONS: Lessee shall not make any alterations or add any fixtures to the Premises or any other aspect of the Building. 

  

	14.	REPAIRS: 

  

	 	(a)	 Lessor’s Obligations: Lessor agrees to repair and maintain the structural portions of the Building and the plumbing, heating, ventilating, air
conditioning, elevator and electrical systems installed or furnished by Lessor, unless such maintenance and repairs are (i) attributable to items installed in Lessee’s Premises which are above standard interior improvements (such as, for
example, custom lighting, special HVAC 

  

 - 6 - 

	 	 
and/or electrical panels or systems, kitchen or rest room facilities and appliances constructed or installed within Lessee’s Premises) or (ii) caused in
part or in whole by the act, neglect or omission of Lessee, its agents, servants, employees or invitees, in which case Lessee will pay to Lessor, as additional rent, the reasonable cost of such maintenance and repairs. Except as provided in this
Subparagraph 14(a), Lessor has no obligation to alter, remodel, improve, repair, decorate or paint the Premises or any part thereof. Lessor’s sole obligation with respect to the provisions of telephone or telecommunication services shall be to
provide an interface with the telephone network at the demarcation point supplied by the local public utility and cable pairs in an amount consistent with the engineering standards to which the Building was designed. Lessor will not be liable for
any failure to make any repairs or to perform any maintenance unless such failure shall persist for an unreasonable time after written notice of the need of such repairs or maintenance is given by Lessor by Lessee. Except as provided in Paragraph
20, Lessee will not be entitled to any abatement of rent and Lessor will not have any liability by reason of any injury to or interference with Lessee’s business arising from the making of any repairs, alterations or improvements in or to any
portion of the Building or the Premises or in or to fixtures, appurtenances and equipment therein. Lessee shall notify Lessor prior to exercising its right to make repairs at Lessor’s expense under any laws, statute, ordinance, rule,
regulation, order or ruling (including, without limitation, to the extent the Premises are located in California, the provisions of California Civil Code Sections 1941 and 1942 and any successor statutes or laws of a similar nature).

  

	 	(b)	Lessee’s Obligations: Lessee agrees to keep, maintain and preserve the Premises in the same condition as received and repair any damage to the Premises arising from any
action or omission by Lessee at Lessee’s sole cost and expense. Any such maintenance and repairs will be performed by Lessor’s contractor or by such contractor or contractors as Lessee may choose from an approved list to be submitted by
Lessor. Lessee’s maintenance and repair obligation shall include the obligation to maintain and repair all the wire between the distribution terminal on the floor where the Premises are located and the telephone jack(s) in the Premises (such
wire is hereafter referred to as “Network Terminating Wire”) and all telephone or telecommunication wiring (including jacks) located within the Premises (hereafter referred to as “Inside Wire”). Lessee agrees to pay all costs and
expenses incurred in such maintenance and repair within thirty (30) days after billing by Lessor or such contractor or contractors. Lessee agrees to cause any mechanics’ liens or other liens arising as a result of work performed by Lessee or at
Lessee’s direction to be eliminated as provided in Paragraph 15 below. If Lessee refuses or neglects to repair and maintain the Premises properly as required hereunder to the reasonable satisfaction of Lessor, Lessor, at any time following ten
(10) days from the date on which Lessor makes a written demand on Lessee to effect such repair and maintenance, may enter upon the Premises and make such repairs and/or maintenance, and upon completion thereof, Lessee agrees to pay to Lessor as
additional rent, Lessor’s reasonable costs for making such repairs plus an amount not to exceed five percent (5%) of such costs for overhead, within thirty (30) days of receipt from Lessor of a written itemized bill therefor. Any amounts not
reimbursed by Lessee within such thirty (30) day period will bear interest at the Interest Rate until paid by Lessee. 

  

	15.	LIENS: Lessee agrees not to permit any mechanic’s, materialmen’s or other liens to be filed against all or any part of the Building, the Building or the Premises,
nor against Lessee’s leasehold interest in the Premises, by reason of or in connection with any repairs, alterations, improvements or other work contracted for or undertaken by Lessee or any other act or omission of Lessee or Lessee’s
agents, employees, contractors, licensees or invitees. At Lessor’s request, Lessee agrees to provide Lessor with an enforceable, and final lien release (or other evidence reasonably requested by Lessor to demonstrate protection from liens) from
all persons furnishing labor and/or materials at the Premises. Lessor will have the right at all reasonable times to post on the Premises and record any notices of nonresponsibility which it deems necessary for protection from such liens. If any
such liens are filed, Lessee will, at its sole cost and expense, promptly cause such liens to be released so that it in longer affects title to the Building, the Building or the Premises. If lessee fails to cause any such liens to be so released or
bonded within thirty (30) days after filing thereof, such failure will be deemed a material breach by Lessee under the Lease without the benefit of any additional notice or cure period described in Paragraph 22 below, and Lessor may, without waiving
its rights and remedies based on such breach, and without releasing Lessee from any of its obligations, cause such liens to be released by any reasonable means it shall deem proper, including payment in satisfaction of the claims giving rise to such
liens. Lessee agrees to pay to Lessor within thirty (30) days after receipt of invoice from Lessor, any sum paid by Lessor to remove such liens, together with interest at the Interest Rate from the date of such payment by Lessor.

  

	16.	ENTRY BY LANDLORD: Lessor and its employees and agents will at all reasonable times have the right to enter the Premises to inspect the same, to supply janitorial service and
any other service to be provided by Lessor to Lessee hereunder, to show the Premises to prospective purchasers or lessees, to post notices of nonresponsibility, and/or to repair the Premises as permitted or required by this Lease. In exercising such
entry rights, Lessor will endeavor to minimize, as reasonably practicable, the interference with Lessee’s business, and will provide Lessee with reasonable advance notice of any such entry (except in emergency situations). Lessor will at all
times have and retain a key with which to unlock all doors in the Premises, excluding Lessee’s vaults and sales. Except in the case of the gross negligence or willful misconduct of Lessor, any entry to the Premises obtained by Lessor will not
be construed or deemed to be a forcible or unlawful entry into the Premises, or an eviction of Lessee from the Premises. 

  

	17.	 UTILITIES AND SERVICES: Throughout the Term of the Lease so long as the Premises are occupied, Lessor agrees to furnish or cause to be furnished to the
Premises the utilities and services described in the Standards for Utilities and Services attached hereto as Exhibit “F”. Except for Lessor’s gross negligent or willful 

  

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misconduct Lessor will not be liable to Lessee for any failure to furnish any of the foregoing utilities and services if such failure is caused by all or any
of the following: (i) accident, breakage or repairs; (ii) strikes, lockouts or other labor disturbance or labor dispute of any character; (iii) governmental regulation, moratorium or other governmental action or inaction; (iv) inability despite the
exercise of reasonable diligence to obtain electricity, water or fuel; or (v) any other cause beyond Lessor’s reasonable control. In addition, in the event of any stoppage or interruption of services or utilities, Lessee shall not be entitled
to any abatement or reduction of rent (except as expressly provided in Subparagraphs 20(f) or 21(b) if such failure results from a damage or laking described therein), no eviction of Lessee will result from such failure and Lessee will not be
relieved from the performance of any covenant or agreement in this Lease because of such failure. In the event of any failure, stoppage or interruption thereof, Lessor agrees to diligently attempt to resume service promptly. If Lessee requires or
utilizes an unreasonably greater amount of water or electrical power, Lessor may at its option require Lessee to pay, as additional rent, the cost, as reasonably determined by Lessor, incurred by such extraordinary usage and/or Lessor may install
separate meter(s) for the Premises, at Lessee’s sole expense, and Lessee agrees thereafter to pay all shares of the utility providing service. 

  

	18.	ASSUMPTION OF RISK AND INDEMNIFICATION: 

  

	 	(a)	Assumption of Risk: Except with respect to Lessor’s gross negligence or willful misconduct, Lessee, as a material part of the consideration to Lessor, agrees that
neither Lessor nor any Lessor Indemnified Parties (as defined in Subparagraph 8(c) above) will be liable to Lessee for, and Lessee expressly assumes the risk of and waives any and all claims it may have against Lessor or any Lessor Indemnified
Parties with respect to, (i) any and all damage to property or injury to persons in, upon or about the premises, the Building or the Building caused by other tenants or persons in or about the Building or the Building, or caused by quasi-public
work, unless Lessor is legally responsible for such third parties’ actions or omissions; (ii) any damage to property entrusted to employees of the Building, unless Lessee entrusted the property to an employee of the Building at Lessor’s
direction; (iii) any loss of or damage to property by theft or otherwise, unless such theft or damage resulted from a breach by Lessor of any legal duty; or (v) any injury or damage to person or property resulting from any casualty, explosion,
falling plaster or other masonry or glass, steam, gas, electricity, water or rain which may leak from any part of the Building or any other portion of the Building or from the roof, street or subsurface or from any other place, or resulting from
dampness, unless Lessor is legally responsible for such condition. Neither Lessor nor any Lessor Indemnified Parties will be liable for consequential damages arising out of any loss of the use of the Premises or any equipment or facilities therein
by Lessee or any Lessee Parties or for interference with light. Lessee agrees to give prompt notice to Lessor in case of fire or accidents in the Premises or the Building, or of defects therein or in the fixtures or equipment that may come to
Lessee’s attention. 

  

	 	(b)	Indemnification: 

  
 (1) Each party (the “Indemnifying Party”) will be liable for, and agrees to the maximum extent permissible under applicable law, to promptly
indemnify, protect, defend and hold harmless the other party (the “Indemnified Party”) and their partners, officers, directors, employees, agents, contractors, invitees, successors and assigns (the “Indemnified Parties”) from and
against, any and all claims, damages, judgments, suits, causes of action, losses, liabilities, penalties, fines, expenses and costs, including reasonable attorney’s fees and court costs (collectively, “Lessee Indemnified Claims”),
arising or resulting from (i) any act or omission of the Indemnifying Party and their partners, officers, directors, employees, agents, contractors, invitees, successors and assigns (the “Indemnifying Parties”); (ii) the use of the
Premises and Common Areas by the Indemnifying Parties, or any other activity, work or thing done, permitted or suffered by the Indemnifying Parties, in or about the Premises, the Building or elsewhere within the Building; and/or (iii) any default by
the Indemnifying Party or any obligations on the Indemnifying Party’s part to be performed under the terms of this Lease. In case any action or proceeding is brought against the Indemnified Party or any Indemnified Parties by reason of any such
Indemnified Claims, the Indemnifying Party, upon notice from the Indemnified Party, agrees to promptly defend the same at the Indemnifying Party’s sole cost and expense. The Indemnifying Party shall have the authority to control the defense of
any such Indemnified Claims provided that the Indemnifying Party shall not settle such Indemnified Claim without the Indemnified Party’s written consent. Notwithstanding the foregoing provisions of this Subparagraph, Lessee shall have no
liability hereunder for claims, damages, judgments, suits, causes of action, losses, liabilities, penalties, fines, expenses and costs, including attorneys’ fees and court costs to the extent arising from the gross negligence or willful
misconduct of Lessor or any Lessor Indemnified Parties. 
  
 (2)
Lessor will be liable for, and agrees to the maximum extent permissible under applicable law, to promptly indemnify, protect, defend and hold harmless Lessee from and against, any and all claims, damages, judgments, suits, causes of action, losses,
liabilities, penalties, fines, expenses and costs, including attorneys’ fees and court costs (collectively, “Lessor Indemnified Claims”), arising or resulting from the grossly negligent or intentionally willful act or omission of
Lessor or its agent or employees. 
  

	 	(c)	Survival; No Release of Insurers: The indemnification obligations under Subparagraph 18(b) shall survive the expiration or earlier termination of this Lease. The
parties’ covenants, agreements and the indemnification obligations in Subparagraphs 18(a) and 18(b) above, are not intended to and will not relieve any insurance carrier of its obligations under policies required to be carried pursuant to the
provisions of this Lease. 

  

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	19.	INSURANCE: 

  

	 	(a)	Lessee’s Insurance: On or before the earlier to occur of (i) the Commencement Date, or (ii) the date Lessee commences any work of any type in the Premises pursuant to
this Lease (which may be prior to the Commencement Date), and continuing throughout the entire Term hereof and any other period of occupancy, Lessee agrees to keep in full force and effect, at it sole cost and expense, the insurance specified on
Exhibit “D” attached hereto. Lessor reserves the right to require any other form or forms of insurance as Lessee or Lessor or any mortgagees of Lessor may reasonably require from time to time in form, in amounts, and for insurance risks
against which, a prudent lessee would protect itself, but only to the extent coverage for such risks and amounts are available in the insurance market at commercially acceptable rates. Lessor makes no representation that the limits of liability
required to be carried by Lessee under the terms of this Lease are adequate to protect Lessee’s interests and Lessee should obtain such additional insurance or increased liability limits as Lessee deems appropriate. 

  

	 	(b)	Supplemental Lessee Insurance Requirements: All policies must be in a form reasonably satisfactory to Lessor and issued by an insurer admitted to do business in the state in
which the Building is located. All policies must be issued by insurers with a policyholder rating of “A” and a financial rating of “X” in the most recent version of Best’s Key Rating Guide. All policies must contain a
requirement to notify Lessor (and Lessor’s property manager and any mortgagees or ground lessors of Lessor who are named as additional insurers, if any) in writing not less than thirty (30) days prior to any material change, reduction in
coverage, cancellation or other termination thereof. Lessee agrees to deliver to Lessor, as soon as practicable after placing the required insurance, but in any event within the time frame specified in Subparagraph 19(a) above, certificate(s) of
insurance and/or if required by Lessor, certified copies of each policy evidencing the existence of such insurance and Lessee’s compliance with the provisions of this Paragraph 19. Lessee agrees to cause replacement policies or certificates to
be delivered to Lessor not less than thirty (30) days prior to the expiration of any such policy or policies. If any such initial or replacement policies or certificates are not furnished within the time(s) specified herein, Lessor will have the
right, but not the obligation, to obtain such insurance as Lessor deems necessary to protect Lessor’s interests at Lessee’s expense. If Lessor obtains any insurance that is the responsibility of Lessee under this Paragraph 19, Lessor
agrees to deliver to Lessee a written statement setting forth the cost of any such insurance and showing in reasonable detail the manner in which it has been computed and Lessee agrees to promptly reimburse Lessor for such costs as additional rent.
General Liability and Automobile Liability policies under Paragraphs 1 and 5 of Exhibit “D” attached hereto must name Lessor and Lessor’s property manager (and at Lessor’s request, Lessor’s mortgagees and ground lessors of
which Lessee has been informed in writing) as additional insured and must also contain a provision that the insurance afforded by such policy is primary insurance and any insurance carried by Lessor and Lessor’s property manager of
Lessor’s mortgagees or ground lessors, if any, will be excess over and non-contributing with Lessee’s insurance. Lessee shall deliver to Lessor, along with the certificate of insurance mentioned above, an endorsement listing Lessor as
additional insured. 

  

	 	(c)	Lessee’s Use: Lessee will not keep, use, sell or offer for sale in or upon the Premises any article which may be prohibited by any insurance policy periodically in force
covering the Building or the Development Common Areas. If Lessee’s occupancy or business in, or on, the premises, whether or not Lessor has consented to the same, results in any increase in premiums for the insurance periodically carried by
Lessor with respect to the Building or the Development or results in the need for Lessor to maintain special or additional insurance, Lessee agrees to pay Lessor the cost of any such increase in premiums or special or additional coverage as
additional rent within ten (10) days after being billed therefore by Lessor. Lessee agrees to promptly comply with all reasonable requirements of the insurance authority or any present or future insurer relating to the Premises.

  

	 	(d)	Cancellation of Lessor’s Policies: If any of Lessor’s insurance policies are canceled or cancellation is threatened or the coverage reduced or threatened to be
reduced in any way because of the use of the Premises or any part thereof by Lessee or any assignee or subtenant of Lessee or by anyone Lessee permits on the Premises and, if Lessee fails to remedy the condition giving rise to such cancellation,
threatened cancellation, reduction of coverage, threatened reduction of coverage, increase in premiums, or threatened increase in premiums, within forty-eight (48) hours after notice thereof, Lessee will be deemed to be in material default of this
Lease and Lessor may, at its option, either terminate this Lease or enter upon the Premises and attempt to remedy such condition, and Lessee shall promptly pay Lessor the reasonable costs of such remedy as additional rent. If Lessor is unable, or
elects not to remedy such condition, then Lessor will have all of the remedies provided for in this Lease in the event of a default by Lessee. 

  

	 	(e)	Waiver of Subrogation: Lessor’s and Lessee’s property and liability insurance shall contain a clause whereby the insurer waives all rights of recovery by way of
subrogation against Lessee and Lessor respectively. Lessee shall also obtain and furnish evidence to Lessor of the waiver by Lessee’s workers compensation insurance carrier of all rights or recovery by way of subrogation against Lessor and
Lessor shall do the same with respect to its workers compensation insurance. 

  

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	20.	DAMAGE OR DESTRUCTION: 

  

	 	(a)	Destruction: If the Premises or the Building are damaged by fire or other casualty to an extent exceeding fifty percent (50%) of the full replacement cost thereof,
Lessee may terminate this Lease effective as of the date which is ten (10) days after Lessor’s receipt of Lessee’s election to so terminate. 

  

	 	(b)	Notice: Under any of the conditions of Subparagraph 20(a) or (b) above, Lessor agrees to give written notice to Lessee of its intention to repair or terminate, as permitted
in such paragraphs, within the earlier of sixty (60) days after the occurrence of such casualty, or fifteen (15) days after Lessor’s receipt of the estimate from Lessor’s contractor (the applicable time period to be referred to herein as
the “Notice Period”). 

  

	 	(c)	Termination Rights: If Lessor elects to repair, reconstruct and restore pursuant to Subparagraph 20(b) (i) hereinabove, and if Lessor’s contractor estimates that
as a result of such damage, Lessee cannot be given reasonable use of and access to the Premises within thirty (30) days after the date of such damage, then either Lessor or Lessee may terminate this Lease effective upon delivery of written notice to
the other within ten (10) days after Lessor delivers notice to Lessee of its election to so repair, reconstruct or restore. 

  

	 	(d)	Lessee’s Costs and Insurance Proceeds: In the event of any damage or destruction of all or any part of the Premises, Lessee agrees to immediately (i) notify
Lessor thereof, and (ii) deliver to Lessor all property insurance proceeds received by Lessee with respect to any tenant improvements installed by or at the cost of Lessee and any alterations, but excluding proceeds for Lessee’s furniture,
trade fixtures, equipment and other personal property, whether or not this Lease is terminated as permitted in this Paragraph 20, and Lessee hereby assigns to Lessor all rights to receive such insurance proceeds. If, for any reason (including
Lessee’s failure to obtain insurance for the full replacement cost of any Lessee Improvements installed by or at the cost of Lessee and any alterations from any and all casualties), Lessee fails to receive insurance proceeds covering the full
replacement cost of any such tenant improvements and any alterations which are damaged. Lessee will be deemed to have self-insured the replacement cost of such item’s, and upon any damage or destruction thereto, Lessee agrees to immediately pay
to Lessor the full replacement cost of such item’s, less any insurance proceeds actually received by Lessor from Lessor’s of Lessee’s insurance with respect to such item’s. 

  

	 	(e)	Abatement of Rent: In the event of any damage, repair, reconstruction and/or restoration described in this Paragraph 20, rent will be abated or reduced, as the case
may be, from the date of such casualty, in proportion to the degree to which Lessee’s use of the Premises is impaired during such period of repair until such use is restored. Except for abatement of rent as provided hereinabove or as provided
by law, Lessee will not be entitled to any compensation or damages for loss of, or interference with, Lessee’s business or use or access of all or any part of the Premises or for lost profits or any other consequential damages of any kind or
nature, which result from any such damage, repair, reconstruction or restoration. 

  

	 	(f)	Damage Near End of Term: Lessor and Lessee shall each have the right to terminate this Lease if any damage to the Premises or the Building occurs during the last
twelve (12) months of the Term of this Lease where Lessor’s contractor estimates in writing delivered to Lessor and Lessee the repair, reconstruction or restoration of such damage cannot be complete within sixty (60) days after the date of such
casualty or during the balance of the term. If either party desires to terminate this Lease under this Subparagraph (20g), it shall provide written notice to the other party of such election within ten (10) days after receipt of Lessor’s
contractor’s repair estimates. 

  

	21.	EMINENT DOMAIN: 

  

	 	(a)	Substantial Taking: If the whole of the Premises, or such part thereof as shall substantially interfere with Lessee’s use and occupancy of the Premises, as
contemplated by this Lease, is taken for any public or quasi-public purpose by any lawful power or authority by exercise of the right of appropriation, condemnation or eminent domain, or sold to prevent such taking, either party will have the right
to terminate this Lease effective as of the date possession is required to be surrendered to such authority. 

  

	 	(b)	Partial Taking: Abatement of Rent: In the event of a taking of a portion of the Premises which does not substantially interfere with Lessee’s use and
occupancy of the Premises, then, neither party will have the right to terminate this Lease and Lessor will thereafter proceed to make a functional unit of the remaining portion of the Premises (but only to the extent Lessor receives proceeds
therefor from the condemning authority), and rent will be abated with respect to the part of the premises which Lessee is deprived of on account of such taking. Notwithstanding the immediately preceding sentence to the contrary, if any part of the
Building or the Building is taken (whether or not such taking substantially interferes with Lessee’s use of the Premises), Lessor may terminate this Lease upon thirty (30) day’s prior written notice to Lessee. 

  

	 	(c)	 Condemnation Award: In connection with any taking of the Premises of the Building, Lessor will be entitled to receive the entire amount of any award
which may be made or given in such taking or condemnation, without deduction or apportionment for any estate or interest of Lessee, it being expressly understood and agreed by Lessee that no portion of any such award will be allowed or paid to
Lessee for any so-called bonus or excess value will be the sole property of Lessor. Lessee agrees not to assert any claim against Lessor or the taking authority for any compensation because of such taking (including any claim for bonus or excess
value of this Lease); provided, however, if any portion of the Premises is taken, Lessee will have the right to recover from the condemning authority (but not from Lessor) any 

  

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compensation as may be separately awarded or recoverable by Lessee for the taking of Lessee’s furniture, fixtures, equipment and other personal property
within the Premises, for Lessee’s relocation expenses, and for any loss of goodwill or other damage to Lessee’s business by reason of such taking. 

  

	 	(d)	Temporary Taking: In the event of taking of the Premises or any part thereof for temporary use, (i) this Lease will remain unaffected thereby and rent will not abate, and
(ii) Lessee will be entitled to receive such portion or portions of any award made for such use with respect to the period of the taking which is within the Term, provided that if such taking remains in force at the expiration or earlier termination
of this Lease, Lessee will then pay to Lessor a sum equal to the reasonable cost of performing Lessee’s obligations under Paragraph 11 with respect to surrender of the Premises and upon such payment Lessee will be excused from such obligations.
For purpose of this Subparagraph 21(d), a temporary taking shall be defined as a taking for a period of sixty (60) days or less. 

  

	22.	DEFAULTS AND REMEDIES: 

  

	 	(a)	Defaults: The occurrence of any one or more of the following events will be deemed a default by Lessee: 

  

	 	(i)	The abandonment or vacating of the Premises by Lessee. Unless Lessee otherwise notifies Lessor, the Premises will be deemed abandoned if Lessee does not occupy premises for
twenty-five (25) consecutive business days. 

  

	 	(ii)	The failure by Lessee to make any payment of rent or additional rent or any other payment required to be made by Lessee hereunder, as and when due, where such failure continues for
a period of five (5) business days after written notice thereof from Lessor to Lessee. 

  

	 	(iii)	The failure by Lessee to observe or perform any of the express covenants or provisions of this Lease to be observed or performed by Lessee, other than as specified in Subparagraph
22(a) (i) or (ii) above, where such failure continues for a period of five (5) business days after written notice thereof from Lessor to Lessee. If the nature of Lessee’s default is such that more than five (5) business days are reasonably
required for its cure, then Lessee will not be deemed to be in default if Lessee commences such cure within such five (5) business days period and thereafter diligently pursues such cure to completion. 

  

	 	(iv)	(A) the making by Lessee of any general assignment for the benefit of creditors; (B) the filing by or against Lessee of a petition to have Lessee adjudged a bankrupt or a petition
for reorganization or arrangement under any law relating to bankruptcy (unless, in the case of a petition filed against Lessee, the same is dismissed within sixty (60) days); (C) the appointment of a trustee or receiver to take possession of
substantially all of Lessee’s assets located at the Premises or of Lessee’s interest in this Lease, where possession is not restored to Lessee within thirty (30) days, or (D) the attachment, execution or other judicial seizure of
substantially all of Lessee’s assets located at the Premises or of Lessee’s interest in this Lease where such seizure is not discharged within thirty (30) days. 

  

	 	(b)	Lessor’s Remedies; Termination: In the event of any default by Lessee, in addition to any other remedies available to Lessor at law or in equity under applicable
law, Lessor will have the immediate right and option to terminate this Lease and all rights of Lessee hereunder. If Lessor elects to terminate this Lease then, to the extent permitted under applicable law, Lessor may recover from Lessee: (i) the
worth at the time of award of any unpaid rent which had been earned at the time of such termination; plus (ii) the worth at the time award of the amount by which the unpaid rent which would have been earned after termination until the time of award
exceeds the amount of such rent loss that could have been reasonably avoided; plus (iii) the worth at the time of award of the amount by which the unpaid rent for the balance of the Term after the time of award exceeds the amount of such rent loss
that could be reasonably avoided; plus (iv) any other amount necessary to compensate Lessor for any damages proximately caused by Lessee’s breach of any of its obligations under this Lease including, but not limited to: reasonable
attorneys’ fees, brokers’ commissions; the costs of refurbishment, alterations, renovation and repair of the Premises made necessary by Lessee’s breach, and removal (including the repair of any damage caused by such removal) and
storage (or disposal) of Lessee’s personal property, equipment, fixtures, alterations, the tenant improvements and any other items which Lessee is required under this Lease to remove but does not remove. As used in Subparagraphs 22(b) (iii)
above, the “worth at the time of award” is computed by discounting such amount at the discount rate of the Federal Reserve Bank of San Francisco at the time of award plus one percent (1%). 

  

	 	(c)	Right to Recover Rent as It Becomes Due: Provided that Lessee has not terminated the Lease, Lessor may exercise the remedy described in California Civil Code Section
1951.4 (Lessor may continue lease in effect after lessee’s breach and abandonment, and recover rent as it becomes due, if lessee has right to sublet or assign, subject only to reasonable limitations). Lessee hereby specifically acknowledges and
agrees that the limitations on its right to sublet or assign, as set forth in Paragraph 24 or the Lease, are reasonable. 

  

 - 11 - 

	 	(d)	Lessor’s Remedies; Re-Entry Rights: In the event of any default by Lessee, in addition to any other remedies available to Lessor under this Lease, at law or in equity,
Lessor will also have the right, with or without terminating this Lease, to re-enter the Premises and reasonably remove all persons and property from the Premises; such property may be removed and stored in a public warehouse or elsewhere and/or
disposed of, as is reasonable under the circumstances, at the sole cost and expense of and for the account of Lessee in accordance with the provisions of Paragraph 13 of this Lease or any other procedures permitted by applicable law. No reasonable
re-entry or taking possession of the Premises by Lessor pursuant to this Subparagraph 22 (d) will be construed as an election to terminate this Lease unless a written notice of such intention is given to Lessee or unless the termination thereof is
decreed by a court of competent jurisdiction. 

  

	 	(e)	Lessor’s Remedies; Re-Letting: If Lessor does not elect to terminate this Lease, Lessor may from time to time, without terminating this Lease, either recover all
rent as it becomes due or relet the Premises or any part thereof on reasonable terms and conditions with the right to make reasonable alterations and repairs to the Premises in connection with such reletting. If Lessor elects to relet the Premises,
then rents received by Lessor from such reletting will be applied: first, to the payment of any indebtedness other than rent due hereunder from Lessee to Lessor; second, to the payment of the reasonable cost of such reletting; third, to the payment
of the reasonable cost of any alterations and repairs to the Premises incurred in connection with such reletting; fourth, to the payment of rent due and unpaid hereunder and the residue, if any, will be held by Lessor and applied to payment of
future rent as the same may become due and payable hereunder. Should that portion of such rents received from such relatting during any month, which is applied to the payment of rent hereunder, be less than the rent payable during that month by
Lessee hereunder, then Lessee agrees to pay such deficiency to Lessor within thirty (30) days of demand therefore by Lessor. Such deficiency will be calculated and paid monthly. 

  

	 	(f)	Lessor’s Remedies; Performance for Lessee: All covenants and agreements to be performed by Lessee under any of the terms of this Lease are to be performed
by Lessee at Lessee’s sole cost and expense and without any abatement of rent. If Lessee fails to pay any sum of money owed to any party other than Lessor, for which its is liable under this Lease, or if Lessee fails to perform any other act on
its part to be performed hereunder, and such failure continues for ten (10) days after notice thereof by Lessor, Lessor may, without waiving or releasing Lessee from its obligations, but shall not be obligated to, make any such payment or perform
any such other act to be made or performed by Lessee. Lessee agrees to reimburse Lessor upon demand for all sums so paid by Lessor and all necessary incidental costs, together with interest thereon at the Interest Rate, from the date of such payment
by Lessor until reimbursed by Lessee. This remedy shall be in addition to any other right or remedy of Lessor set forth in this Paragraph 22. 

  

	 	(g)	Late Payment: If Lessee fails to pay any installment of rent within five (5) days of when due or it Lessee fails to make any other payment for which Lessee is
obligated under this Lease within five (5) days of when due, such late amount will accrue interest at the Interest Rate and Lessee agrees to pay Lessor as additional rent such interest on such amount from the date such amount becomes due until such
amount is paid. In addition, Lessee agrees to pay to Lessor concurrently with such late payment amount, as additional rent, a late charge equal to ten percent (10%) of the amount due to compensate Lessor for the extra costs Lessor will incur as a
result of such late payment. Acceptance of any such interest will not constitute a waiver of the Lessee’s default with respect to the overdue amount, or prevent Lessor from exercising any of the other rights and remedies available to Lessor. If
Lessee incurs a late charge more than three (3) times in any period of twelve (12) months during the Lease Term, then, notwithstanding that Lessee cures the late payments for which such late changes are imposed, Lessor will have the right to require
Lessee thereafter to pay all installments of Monthly Base Rent quarterly in advance throughout the remainder of the Lease Term. 

  

	 	(h)	Rights and Remedies Cumulative: All rights, options and remedies of Lessor to the extent permitted by applicable law contained in this Lease will be construed and held to be
cumulative, and no one of them will be exclusive of the other, and Lessor shall have the right to pursue any one or all of such remedies or any other remedy or relief which may be provided by law or in equity, whether or not stated in this Lease.
Nothing in this Paragraph 22 will be deemed to limit or otherwise affect Lessee’s indemnification of Lessor pursuant to any provision of this Lease. 

  

	23.	LESSOR’S DEFAULT: Lessor will not be in default in the performance of any obligation required to be performed by Lessor under this Lease unless Lessor fails to perform
such obligation within fifteen (15) business days after the receipt of written notice from Lessee specifying in detail Lessor’s failure to perform; provided however, that if the nature of Lessor’s obligation is such that more than fifteen
(15) business days are required for performance, then Lessor will not be deemed in default if it commences such performance within such fifteen (15) business day period and thereafter diligently pursues the same to completion. Upon any default by
Lessor, Lessee may exercise any of its rights provided at law or in equity, subject to the limitations on liability set forth in Paragraph 35 of this Lease. 

  

	24.	ASSIGNMENT AND SUBLETTING: 

  

	 	(a)	 Restriction on Transfer: Except as expressly provided in this Paragraph 24, Lessee will not, either voluntarily or by operation of law, assign or encumber
this Lease or any interest herein or sublet the Premises or any part thereof, or permit the use or occupancy of the Premises by any party other than Lessee (any such assignment, encumbrance, sublease or the like will sometimes be referred to as a
“Transfer”), without the prior written consent of Lessor, which consent Lessor will not unreasonably 

  

 - 12 - 

	 	 
withhold. For purposes of this Paragraph 24, if Lessee is a corporation, partnership or other business entity, any transfer, assignment, encumbrance or
hypothecation of more than sixty percent (60%) (individually or in the aggregate) of any stock or other ownership interest in such entity, and/or any transfer, assignment, hypothecation or encumbrance of any controlling ownership or voting interest
in such entity, will be deemed a Transfer and will be subject to all of the restrictions and provisions contained in this Paragraph 24. 

  

	 	(b)	Transfer Notice: If Lessee desires to effect a Transfer, then at least thirty (30) days prior to the date when Lessee desires the Transfer to be effective (the
“Transfer Date”), Lessee agrees to give Lessor a notice (the “Transfer Notice”), stating the name, address and business of the proposed assignee, sublessee or other transferee (sometimes referred to hereinafter as
“Transferee”), reasonable information (including references) concerning the character, ownership and financial condition of the proposed Transferee, the Transfer Date, any ownership or commercial relationship between Lessee and the
proposed Transferee, and the consideration and all other material terms and conditions of the proposed Transfer, all in such detail as Lessor may reasonably require. 

  

	 	(c)	Lessor’s Options: Within fifteen (15) days of Lessor’s receipt of any Transfer Notice, and any additional information requested by Lessor concerning the
proposed Transferee’s financial responsibility, Lessor will notify Lessee of its election to do one of the following: (i) consent to the proposed Transfer subject to such reasonable conditions as Lessor may impose in providing such consent, or
(ii) refuse such consent; which refusal shall be on reasonable grounds. 

  

	 	(d)	Additional Conditions: A condition to Lessor’s consent to any Transfer of this Lease will be the delivery to Lessor or a true copy of the fully executed
instrument of assignment, sublease, transfer or hypothecation, in form and substance reasonably satisfactory to Lessor. Tenant shall pay to Landlord monthly, as additional rent, at the same time as the monthly installments of Rent are payable
hereunder, any consideration paid by the Transferee for the Transfer, including, in the case of a sublease, the excess of fifty percent (50%) of the rent and other consideration payable by the subtenant over the amount of Base Rent and Additional
Rent payable hereunder applicable to the subleased space; provided that Tenant’s obligation to pay such portion of excess Transfer consideration to Landlord shall not arise until Tenant has recovered from such excess Transfer consideration,
Tenant’s expenses on account of such Transfer (which shall be limited to reasonable advertising costs, costs of tenant improvements provided by Tenant, brokerage commissions, and reasonable legal fees.). No Transfer will release Lessee of
Lessee’s obligations under this Lease or alter the liability of Lessees to pay the rent and to perform all other obligations to be performed by Lessee hereunder. Lessor may require that any Transferee (i) remit directly to Lessor on a monthly
basis, all monies due Lessee by said Transferee and (ii) assume the obligations of Lessee hereunder occurring after the date of transfer. Consent by Lessor to one Transfer will no be deemed consent to any subsequent Transfer. In the event of default
by any Transferee of Lessee or any successor of Lessee in the performance of any of the terms hereof, Lessor may proceed directly against Lessee without the necessity of exhausting remedies against such Transferee or successor. If Lessee affects a
Transfer or requests the consent of Lessor to any Transfer (whether or not such Transfer is consummated), then, upon demand, Lessee agrees to pay Lessor a non-refundable administrative fee of Two Hundred Fifty Dollars ($250.00), plus Lessor’s
reasonable attorneys’ fees. 

  

	25.	SUBORDINATION: Without the necessity of any additional document being executed by Lessee for the purpose of effecting a subordination, and at the election of
Lessor or any mortgagee or beneficiary with a deed of trust encumbering the Building and/or the Building, or any Lessor of a ground or underlying lease with respect to the Building, this Lease will be subject and subordinate at all times to: (i) all
ground lease or underlying leases which may now exist or hereafter be executed affecting the Building; and (ii) the lien of any mortgage or deed of trust which may now exist or hereafter be executed for which the Building, the Building or any leases
thereof, or Lessor’s interest and estate in any of said items, is specified as security. Notwithstanding the foregoing, Lessor reserves the right to subordinate any such ground leases or underlying leases or any such liens to this Lease. If any
such ground lease or underlying lease terminates for any reason or any such mortgage or deed of trust is foreclosed or a conveyance in lieu of foreclosure is made for any reason, at the election of Lessor’s successor in interest, Lessee agrees
to attorn to and become the lessee of such successor provided that the terms of the Lease relating to Lessee’s rights and responsibilities remain in materially the same form, in which event Lessee’s right to possession of the Premises will
not be disturbed as long as Lessee is not in default under this Lease. Lessee hereby waives its rights under any law which gives or purports to give Lessee any right to terminate or otherwise adversely affect this Lease and the obligations of Lessee
hereunder in the event of any such foreclosure proceeding of sale. Lessee convenants and agrees to execute and deliver, upon demand by Lessor and in the form reasonably required by Lessor, any additional documents evidencing the priority or
subordination of this Lease and Lessee’s attornment agreement with respect to any such ground lease or underlying leases or the lien of any such mortgage or deed of trust. If Lessee fails to sign and return any such documents within ten (10)
days of receipt, Lessee will be in default hereunder. 

  

	26.	 ESTOPPEL CERTIFICATE: Within ten (10) days following any written request which Lessor may make from time to time, Lessee agrees to execute and deliver
to Lessor an estoppel certificate as may reasonably be required by Lessor. Lessor and Lessee intend that any statement delivered pursuant to the Paragraph 26 may be relied upon by any mortgagee, beneficiary, purchaser or prospective purchaser of the
Building or any interest therein. Lessee’s failure to deliver such statement within such time will be conclusive upon Lessee (i) that this Lease is in full force and effect, without modification except as may be represented by Lessor, (ii) that
there are no uncured defaults in Lessor’s performance, and (iii) that not more than one (1) month’s rent has been paid in 

  

 - 13 - 

	 	 
advance. Without limiting the foregoing, if Lessee fails to deliver any such statement within such ten (10) day period, Lessor may deliver to Lessee an
additional request for such statement and Lessee’s failure to deliver such statement to Lessor within ten (10) days after delivery of such additional request will constitute a default under this Lease, Lessee agrees to indemnify and protect
Lessor from and against any and all claims, damages, losses, liabilities and expenses (including reasonable attorneys’ fees and costs) attributable to any failure by Lessee to timely deliver any such estoppel certificate to Lessor as required
by this Paragraph 26. 

  

	27.	BUILDING PLANNING: If Lessor requires the Premises for use in conjunction with another suite or for other reasons connected with the planning program for the Building or the
Building, Lessor will have the right, upon sixty (60) days’ prior written notice to Lessee, to move Lessee to other space in the Building of substantially similar size, accommodations, and features as the Premises, and with lessee improvements
of substantially similar age, quality and layout as then existing in the Premises. Any such relocation will be at Lessor’s cost and expense, including the cost of providing such substantially similar lessee improvements (but not any furniture
or personal property) and Lessee’s reasonable moving, telephone installation and stationary reprinting costs. If Lessor so relocates Lessee, the terms and conditions of this Lease will remain in full force and effect an apply to the new space,
except that (a) a revised Exhibit “A-1” will become part of this Lease and will reflect the location the new space, (b) Paragraph 1 of this Lease will be amended to include and state all correct data as to the new space, (c) the new space
will thereafter be deemed to be the “Premises”, and (d) all economic terms and conditions (e.g. rent, total Base Operating Expense, etc.) will be adjusted on a per square foot basis based on the total number of rentable square feet of area
contained in the new space but in no event greater than the terms and conditions of this lease. Lessor and Lessee agree to cooperate fully with one another in order to minimize the inconvenience to Lessee resulting from any such relocation and the
parties shall execute the amendment of this lease. Upon receipt of written notice from Lessor indicating Lessor’s intent to move Lessee to other space, Lessee shall have the right to Inspect such other space. If Lessee is not satisfied by any
space offered by Lessor pursuant to this Paragraph 27, Lessee shall be entitled to terminate the lease, which shall be effective upon Lessor’s intended move date. 

  

	28.	RULES AND REGULATIONS: Lessee agrees to faithfully observe and comply with the “Rules and Regulations,” a copy of which is attached hereto and incorporated herein
by this reference as Exhibit “H”, and all reasonable and nondiscriminatory modifications thereof and additions thereto from time to time put into effect by Lessor. Lessor will not be responsible to Lessee for the violation or
non-performance by any other lessee or occupant of the Building of any of the Rules and Regulations. 

  

	29.	MODIFICATION AND CURE RIGHTS OF LESSOR’S MORTGAGEES AND LESSORS: If, in connection with Lessor’s obtaining or entering into any financing or ground lease for any
portion of the Building or the Building, the lender or ground lessor requests modifications to this Lease, Lessee, within ten (10) days after request therefor, agrees to execute an amendment to this Lease incorporating such modifications, provided
such modifications are reasonable and do not increase the monetary obligations of Lessee under this Lease or adversely affect the leasehold estate created by the Lease. In the event of any default on the part of Lessor under this Paragraph 29,
Lessee will give written notice to any beneficiary of a deed of trust or mortgage covering the Premises or ground lessor of Lessor whose address has been furnished to Lessee by Lessor, and Lessee agrees to offer such beneficiary, mortgagee or ground
lessor a reasonable opportunity to cure the default (including with respect to any such beneficiary or mortgagee, reasonable time to obtain possession of the Premises, subject to this Lease and Lessee’s rights hereunder, by power of sale or a
judicial foreclose, if such should prove necessary to effect a cure). 

  

	30.	DEFINITION OF LESSOR: The term “Lessor”, as used in this Lease, so far as covenants or obligations on the part of Lessor are concerned, means and includes only the
owner or owners, at the time in question, of the fee title of the Premises or the lessees under any ground lease, if any. In the event of any transfer, assignment or other conveyance or transfers of any such title (other than a transfer for security
purposes only), Lessor herein named (and in case of any subsequent transfers or conveyances, the then grantor) will be automatically relieved from and after the date of such transfer, assignment or conveyance of all liability as respects the
performance of any covenants or obligations on the part of Lessor contained in this Lease thereafter to be performed, so long as the transferee assumes in writing all such covenants and obligations of Lessor arising after the date of such transfer,
Lessor and Lessor’s transferees and assignees have the absolute right to transfer all or any portion of their respective title and interest in the Building, the Building, the Premises and/or this Lease without the consent of Lessee provided
that such transfer does not increase the monetary obligations of Lessee under this Lease or adversely affect the leasehold estate created by the Lease. Any such transfer or subsequent transfer permitted under this Paragraph 30 will not be deemed a
violation on Lessor’s part of any of the terms and conditions of this Lease. 

  

	31.	 WAIVER: The waiver by either party of any breach of any term, covenant or condition herein contained will not be deemed to be a waiver of any subsequent
breach of the same or any other term, covenant or condition herein contained, nor will any custom or practice which may develop between the parties in the administration of the terms hereof be deemed a waiver of or in any way affect the right of
either party to insist upon performance in strict accordance with said terms. The subsequent acceptance of rent or any other payment hereunder by Lessor will not be deemed to be a waiver of any preceding breach by Lessee of any term, covenant or
condition of this Lease, other than the failure of Lessee to pay the particular rent so accepted, regardless of Lessor’s knowledge of such preceding breach at the time of acceptance of such rent. No acceptance by Lesser of a lessor sum than the
basic rent and additional rent or other sum then due will be deemed to be other than on account of the earliest installment if such rent or other amount due, nor will any endorsement or statement on any check or any letter accompanying any check be
deemed an accord and satisfaction, and Lessor may 

  

 - 14 - 

	 	 
accept such check or payment without prejudice to Lessor’s right to recover the balance of such installment or other amount or pursue any other remedy
provided in this Lease. The consent or approval of Lessor to or of any act by Lessee requiring Lessor’s consent or approval will not be deemed to waive or render unnecessary Lessor’s consent or approval to or of any subsequent similar acts
by Lessee. 

  

	32.	PARKING: Lessee shall be entitled to use, in common with other lessees and Lessor and its agents, the number of assigned and/or undesignated vehicle parking spaces allocated
to Lessee in Paragraph 1(I) subject to the terms and conditions of this Paragraph 32 and the Rules and Regulations regarding parking, and the parking contained in Exhibit “I” attached hereto; provided however, that if the size of the
Premises shall hereafter be reduced, whether pursuant to an amendment of lease or any modification to this standard lease form or otherwise, the number of parking spaces allocated to Lessee shall automatically be reduced pro rata. Upon request,
Lessee shall provide Lessor with the license plate numbers of all vehicles used at the Facility by Lessee’s employees. In the event that, pursuant to any modification or amendment to this standard form lease, Lessee is at any time given any
right to the exclusive use of any designated parking stalls or facilities, Lessor shall nevertheless have the right from time to time to substitute other designated parking stalls or facilities therefor, so long as such substitute stalls or
facilities are reasonably comparable. If Lessee parks more vehicles in the Facility’s parking area than are permitted under this Section, Lessor shall have the right, without limitation to Lessor’s other remedies under this Lease, to
collect from Lessee a daily charge, to be reasonably determined by Lessor, for each such additional vehicle. 

  

	33.	FORCE MAJEURE: If either Lessor or Lessee is delayed, hindered in or prevented from the performance of any act or obligation required under this Lease by reason of strikes,
lock-outs, labor troubles, inability to procure standard materials, failure of power, restrictive governmental laws, regulations or orders or governmental action or inaction (including failure, refusal or delay in issuing permits, approvals and/or
authorizations which is not the result of the action or inaction of the party claiming such delay), riots, civil unrest or insurrection, war, fire, earthquake, flood or other natural disaster, unusual and unforeseeable delay which results from an
interruption or any public utilities (e.g., electricity, gas, water, telephone) or other unforeseeable delay not within the reasonable control of the party delayed in performing work or doing acts required under the provisions of this Lease, then
performance of such act or obligation will be excused for the period of the delay and the period for the performance of any such act shall be extended by the length of such delay. If premises can not be occupied for a period exceeding thirty (30)
days, Lessee has the right to terminate the lease. 

  

	34.	SIGNS: Lessor will designate the location of the Premises, if any, for one or more Lessee identification sign(s). Lessee agrees to have Lessor reasonably install and maintain
Lessee’s identification sign(s) in such designated location in accordance with this Paragraph 34 at Lessee’s sole cost and expense. Lessee has no right to install Lessee identification signs in any other location in, on or about the
Premises or the Building and will not display or erect any other signs, displays or other advertising materials that are visible from the exterior of the Building or from within the Building in any interior or exterior common areas. The size,
design, color and other physical aspects or any and all permitted sign(s) will be subject to (i) Lessor’s written approval prior to installation, which approval may be withheld in Lessor’s discretion, (ii) any covenants, conditions or
restrictions governing the Premises, and (iii) any applicable municipal or governmental permits and approvals. Lessee will be solely responsible for all reasonable costs for installation, maintenance, repair and removal of any Lessee identification
sign(s). If Lessee fails to remove Lessee’s sign(s) upon termination of this Lease and repair any damage caused by such removal, Lessor may do so at Lessee’s sole cost and expense. Lessee agrees to reimburse Lessor for all reasonable costs
incurred by Lessor to effect any installation, maintenance or removal on Lessee’s account, which amount will be deemed additional rent, and may include, without limitation, all sums disbursed, incurred or deposited by Lessor including
Lessor’s costs, expenses and actual attorneys’ fees with interest thereon at the Interest Rate from the date of Lessor’s demand until paid by Lessee. Any sign rights granted to Lessee under this Lease are personal to Lessee and may
not be assigned, transferred or otherwise conveyed to any assignee or sublessee of Lessee without Lessor’s prior written consent, which consent Lessor may withhold in its sole and absolute discretion. 

  

	35.	LIMITATION ON LIABILITY: In consideration of the benefits accruing hereunder, Lessee on behalf of itself and all successors and assigns of Lessee covenants and agrees that,
in the event of any actual or alleged failure, breach or default hereunder by Lessor: (a) Lessee’s recourse against Lessor for monetary damages will be limited to Lessor’s interest in the Building including, subject to the prior rights of
any Mortgagee, Lessor’s interest in the rents of the Building and any insurance proceeds payable to Lessor; (b) except as may be necessary to secure jurisdiction of the partnership, no partner of Lessor shall be sued or named as a party in any
suit or action and no service of process shall be made against any partner of Lessor; (c) no partner of Lessor shall be required to answer or otherwise plead to any service of process; (d) no judgment will be taken against any partner of Lessor and
any judgment taken against any partner of Lessor may be vacated and set aside at any time after the fact; (e) no writ of execution will be levied against the assets of any partner of Lessor; (f) the obligations under this Lease do not constitute
personal obligations of the individual partners, directors, officers or shareholders of Lessor, and Lessee shall no seek recourse against the individual partners, directors, officers of shareholders of Lessor or any of their personal assets for
satisfaction of any liability in respect to this Lease; and (g) these covenants and agreements are enforceable both by Lessor and also any partner of Lessor. 

  

	36.	FINANCIAL STATEMENTS: Prior to the execution of this Lease by Lessor and at any time during the Term of this Lease upon ten (10) days prior written notice from Lessor, Lessee
agrees to provide Lessor with a current financial statement for Lessee and any guarantors of Lessee and financial statement for the two (2) years prior to the current financial statement year for Lessee and any guarantors of Lessee. Such statements
are to be prepared in accordance with generally accepted accounting principles and, if such is the normal practice of Lessee, audited by an independent certified public accountant. 

  

 - 15 - 

	37.	QUIET ENJOYMENT: Lessor covenants and warrants that upon Lessee paying the rent required under this Lease and paying all other charges and performing all of the covenants and
provisions on Lessee’s part to be observed and performed under this Lease, Lessee may peaceably and quietly have, hold and enjoy the Premises in accordance with this Lease. 

  

	38.	MISCELLANEOUS: 

  

	 	(a)	Conflict of Laws: This Lease shall be governed by and construed solely pursuant to the laws of the State of California without giving effect to choice of law
principles thereunder. 

  

	 	(b)	Successors and Assigns: Except as otherwise provided in this Lease, all of the covenants, conditions and provisions of this Lease shall be binding upon and shall inure to the
benefit of the parties hereto and their respective heirs, personal representatives, successors and assigns. 

  

	 	(c)	Professional Fees and Costs: If either Lessor or Lessee should bring suit against the other with respect to this Lease, then all reasonable cost and expenses, including
without limitation, professional fees and costs such as appraiser, accountants’ and attorneys’ fees and costs, incurred by the party which prevails in such action, whether by final judgment or out of court settlement, shall be paid by the
other party, which obligation on the part of the other party shall be deemed to have accrued on the date of the commencement of such action and shall be enforceable whether or not the action is prosecuted to judgment. As used herein, attorneys’
fees and costs shall include, without limitation, attorneys’ fees, costs and expenses incurred in connection with any (i) post judgment motions; (ii) contempt proceeding; (iii) garnishment, levy, and debtor and third party examination; (iv)
discovery; and (v) bankruptcy litigation. 

  

	 	(d)	Landlord Renovation: Tenant acknowledges that Landlord may from time to time, at Landlord’s sole option, renovate, improve, develop, alter, or modify (collectively, the
“Renovations”) portions of the Building, Premises, Common Areas and the Building, including without limitation, systems and equipment, roof, and structural portions of the same. In connection with such Renovations, Landlord may, among
other things, erect scaffolding or other necessary structures in the Building, limit or eliminate access to portions of the Building, including portions of the Common Areas, or perform work in the Building, which work may create noise, dust or leave
debris in the Building. Tenant hereby agrees that such Renovations and Landlord’s actions in connection with such Renovations shall in no way constitute a constructive eviction of Tenant or entitle Tenant to any abatement of Rent. Landlord
shall have no responsibility, or for any reason be liable to Tenant, for any direct or indirect injury to or interference with Tenant’s business arising from the Renovations, nor shall Tenant be entitled to any compensation or damages from
Landlord for loss of the use of the whole or any part of the Premises or of Tenant’s property, Alterations or improvements resulting from the Renovations or Landlord’s actions in connection with such Renovations, or for any inconvenience
or annoyance occasioned by such Renovations or Landlord’s actions in connection with such Renovations. If premises cannot be occupied for a period exceeding (30) days, Lessee has the right to terminate that lease. 

  

	 	(e)	Terms and Headings: The words “Lessor” and “Lessee” as used herein shall include the plural as well as the singular. Words used in any gender include
other genders. The paragraph headings of this Lease are not a part of this Lease and shall have no effect upon the construction or interpretation of any part hereof. 

  

	 	(f)	Time: Time is of the essence with respect to the performance of every provision of this Lease in which time of performance is provided. 

  

	 	(g)	Prior Agreement; Amendments: This Lease constitutes and is intended by the parties to be a final, complete and exclusive statement of their entire agreement with
respect to the subject matter of this Lease. This Lease supersedes any and all prior and contemporaneous agreements and understandings of any kind relating to the subject matter of this Lease. There are no other agreements, understandings,
representations, warranties, or statements, either oral or in written form, concerning the subject matter of this Lease. No alteration, modification, amendment or interpretation of this Lease shall be binding on the parties unless contained in a
writing which is signed by both parties. 

  

	 	(h)	Separability: The Provisions of this Lease shall be considered separable such that if any provision or part of this Lease is ever held to be invalid, void or illegal under
any law or ruling, all remaining provisions of this Lease shall remain in full force and effect to the maximum extent permitted by law. 

  

	 	(i)	Recording: Neither Lessor nor Lessee shall record this Lease nor a short form memorandum thereof without the consent of the other. 

  

	 	(j)	Counterparts: This Lease may be executed in one or more counterparts, each of which shall constitute an original and all of which shall be one and the same agreement.

  

	 	(k)	Nondisclosure of Lease Terms: Lessee acknowledges and agrees that the terms of this Lease are confidential and constitute proprietary information of Lessor. Disclosure of the
terms could adversely affect the ability of Lessor to negotiate other leases and impair Lessor’s relationship with other lessees. Accordingly, Lessee agrees that it, and its partners, officers, directors, employees, agents and attorneys, shall
not intentionally and voluntarily disclose the terms and conditions of this Lease to any newspaper of 

  

 - 16 - 

 other publication or any other lessee or apparent prospective lessee of the Building or other portion of
the Building, either directly or indirectly, without the prior written consent of Lessor, provided, however, that Lessee may disclose the terms to prospective sublessees or assignees under this Lease. 
  

	 	(l)	Non-Discrimination: Lessee acknowledges and agrees that there shall be no discrimination against, or segregation of, any person, group of person, or entity on the basis of
race, color, creed, religion, age, sex, marital status, national origin, or ancestry in the leasing, subleasing, transferring, assignment, occupancy, tenure, use, or enjoyment of the Premises, or any portion thereof. 

  

	39.	EXECUTION OF LEASE: 

  

	 	(a)	Joint and Several Obligations: If more than one person or entity executes this Lease as Lessee, their execution of the Lease will constitute their covenant and
agreement that (i) each of the them is jointly and severally liable for the keeping, observing and performing of all of the terms, covenants, conditions, provisions and agreements of this Lease to be kept, observed and performed by Lessee, and (ii)
the term “Lessee” as used in this Lease means and includes each of them jointly and severally. The act of or notice from, or noticed or refund to, or the signature of any one or more of them, with respect to the tenancy of this Lease,
including, but not limited to, any renewal, extension, expiration, termination or modification of this Lease as Lessee with the same force and effect as if each and all of them had so acted or so given or received which notice or refund of so
signed. 

  

	 	(b)	Lessee as Corporation or Partnership: If Lessee executes this Lease as a corporation, limited liability company, or partnership, then Lessee and the persons executing
this Lease on behalf of Lessee represents and warrant that such entity is duly qualified and in good standing to do business in California and that the individuals executing this Lease on Lessee’s behalf are duly authorized to execute and
deliver this Lease on its behalf, and in the case of a corporation, in accordance with a duly adopted resolution of the board of directors of Lessee if the bylaws of lessee require such authorization, a copy of which is to be delivered to Lessor on
execution hereof, if requested by Lessor, and, in the case of a limited liability in accordance the operating agreement and any amendments thereto, and, in the case of a partnership, in accordance with the partnership agreement and the most current
amendments thereto, if any, copies of which are to be delivered to Lessor on execution hereof, if requested by Lessor, and that this Lease is binding upon Lessee in accordance with its terms. 

  

	 	(c)	Examination of Lease: Submission of this instrument by Lessor to Lessee for examination or signature by Lessee does not constitute a reservation of or option for lease, and
it is not effective as a lease or otherwise until execution by and delivery to both Lessor and Lessee. 

  
 IN WITNESS WHEREOF, the parties have caused this Lease to be duly executed by their duly authorized representatives as of the date first above written. 

 

			
	 LESSOR:
	  	 F & S PROPERTIES, LLC,
 a California Limited
Liability company

		
	 By:
	  	 /s/ Todd B. Foster

	 Print Name:
	  	 Todd B. Foster

	 Print Title:
	  	 Partner

	 Date:
	  	 1-12-04

		
	 LESSEE:
	  	 COTHERIX, INC.
 a Delaware corporation

		
	 By:
	  	 /s/ Donald J. Santel

	 Print Name:
	  	 DONALD J. SANTEL

	 Print Title:
	  	 President & COO

	 Date:
	  	 1/09/04

  

 - 17 - 

 EXHIBIT “A-I” 
  
 FLOOR PLAN 
  

 - 18 - 

 EXHIBIT “A-II” 
  
 SITE PLAN 
  
 [GRAPHIC APPEARS HERE] 
  
 [GRAPHIC APPEARS HERE] 
  

 - 19 - 

 EXHIBIT “B” 
  
 ADJUSTMENTS TO MONTHLY BASE RENT 
  
 Commencing February 1, 2004 through March 31, 2004 inclusive, the monthly rent shall be $10,954.00. 
  

 - 20 - 

 EXHIBIT “C” 
  
 DESCRIPTION OF LESSORS WORK 
  
 INTENTIONALLY LEFT BLANK 
  

 - 21 - 

 EXHIBIT “D” 
  
 LESSEE’S INSURANCE REQUIREMENTS 
  
 This outlines the insurance requirements of your Lease. To assure compliance with theses terms, we suggest you send a copy of this Exhibit
to your insurer or agent. Initial Certificates and endorsements must be provided to Lessor prior to occupancy of the Premises and renewals ten (10) days before expiration. 
  

	 	1.	Comprehensive or Commercial General Liability Insurance: 

  
 $1,000,000. Combined Single Limit, each occurrence. 
  
 $1,000,000. Aggregate (minimum) this location. 
  
 $1,000,000. Products/Completed Operations Aggregate. 
  
 $50,000. Fire Legal Liability Limit, per fire, Bodily Injury, Property Damage, Personal Injury and Advertising Injury; Blanket Contractual Liability -
Covering Indemnity Section 18(b); Products and Completed Operations Liability; Lessor as an Additional Insured; Severability of Interest, permitting Cross liability among insured; provision stating that lessee’s insurance is primary and
non-contributing with any insurance carried by Lessor. 
  

	 	2.	Lessee’s Property Insurance: 

  
 All Risks coverage of Property owned by Lessee or for which the Lessee is legally liable; full replacement cost basis. 
  

	 	3.	Lessee’s Business Interruption Insurance: 

  
 All Risks coverage of operations as leased premises; covering one-years business interruption due to insured peril. 
  

	 	4.	Lessee’s Workers’ Compensation and Employer’s Liability Insurance: 

  
 Statutory Limits and terms required by State; $1,000,000. Employer’s Liability Limit: 
  
 All insurance is to be with licensed insurers having a Best’s rating of “A X”
or better, and must include the following: 
  
 Waiver of
Subrogation in favor of Lessor Thirty (30) day pre-notice of cancellation/non renewal to Lessor. 
  
 SEND CERTIFICATE AND ENDORSEMENT TO: 
  
 F & S Properties, LLC 
 c/o Foster Enterprises 
 250A Twin Dolphin Drive 
 Redwood City, CA 94065 
  
 PLEASE INCLUDE
ADDRESS OF PREMISES. 
  
 1301 Shoreway Road,
Suite 320 
 Belmont, CA 94002 
  

 - 22 - 

 EXHIBIT “E” 
  
 DEFINITION OF OPERATING EXPENSES 
  

	1.	Items Included In Operating Expenses. The term “Operating Expenses” as used in the Lease to which this Exhibit “E” is attached means: all costs and
expenses of operation, maintenance and repair of the Building and the Common Areas (as such terms are defined in the Lease), as determined by standard accounting practices, calculated assuming the Building is ninety-five percent (95%) occupied,
including the following costs by way of illustration but not limitation, but excluding those items specifically set forth in Paragraph 3 below: (a) Real Property Taxes and Assessments (as defined in Paragraph 2 below) and any taxes or
assessments imposed in lieu thereof; (b) any and all assessments imposed with respect to the Building pursuant to any covenants, conditions and restrictions affecting the Building, the Common Areas or the Building; (c) water and sewer charges and
the costs of electricity, heating, ventilating, air conditioning and other utilities; (d) utilities surcharges and any other costs, levies or assessments resulting from statutes or regulations promulgated by any government or quasi-government
authority in connection with the use, occupancy or alteration of the Building or the premises or the parking facilities serving the Building or the Premises; (e) costs of insurance obtained by Lessor pursuant to Paragraph 19 of the Lease; (f)
waste disposal and janitorial services; (g) security; (h) labor; (i) costs incurred in the management of the Building, including, without limitation; (i) supplies, (ii) wages and salaries (and payroll taxes and similar governmental charges related
thereto) of employees used in the management, operation and maintenance of the Building, (iii) Building management office rental, supplies, equipment and related operating expenses, and (iv) a management/administrative fee determined as a percentage
of the annual gross revenues of the Building exclusive of the proceeds of financing or a sale of the Building and an administrative lee for the management of the Building Common Area determined as a percentage of Building Common Area Operating
Expenses; (j) supplies, materials, equipment and tools including rental of personal property used for maintenance; (k) repair and maintenance of the elevators and the structural portions of the Building, including the plumbing, heating, ventilating,
air-conditioning and electrical systems installed or furnished by Lessor; (l) maintenance, costs and upkeep of all parking and Building Common areas; (m) depreciation on a straight line basis (n) amortization on a straight line basis over the useful
life [together with interest at the Interest Rate on the unamortized balance] of all capitalized expenditures which are: (i) reasonably intended to produce a reduction in operating charges or energy consumption; or (ii) required under any
governmental law or regulation that was not applicable to the Building at the time it was originally constructed; or (iii) for replacement of any Building equipment needed to operate the Building at the same quality levels as prior to the
replacement; (o) costs and expenses of gardening and landscaping; (p) maintenance of signs (other than signs of Lessees of the Building); (q) personal property taxes levied on or attributable to personal property used in connection with the Building
or the Common Areas; (r) reasonable accounting, audit, verification, legal and other consulting fees, (s) costs and expenses of repairs, resurfacing, repairing, maintenance, painting, lighting, cleaning, refuse removal, security and similar items,
including appropriate reserves, and (t) rental of personal property used in maintenance. When calculating Operating Expenses for purposes of establishing Lessee’s Base Operating Expenses and Real Property Taxes, Operating Expenses shall not
include Real Property Taxes and Assessments attributable to special assessments, charges, costs, or fees or due to modifications or changes in governmental laws or regulations including, but not limited to, the institution of a split tax roll, and
shall exclude market-wide labor-rate increases due to extraordinary circumstances including, but not limited to, boycotts and strikes and utility increases due to extraordinary circumstances including, but not limited to, conservation surcharges,
boycotts, embargoes or other shortages. 

  

	2.	Real Property Taxes. The term “Real Property Taxes”, as used in this Exhibit “E”, means; any form of assessment, license fee, license tax, business
license fee, commercial rental tax, levy charge, improvement bond, tax or similar imposition imposed by any authority having the direct power to tax, including any city, county, state or federal government, or any school, agricultural, lighting,
drainage or other improvement or special assessment district thereof, as against any legal or equitable interest of Lessor in the Premises, Building, Common Areas or the Building (as such terms are defined in the Lease), adjusted to reflect an
assumption that the Building is fully assessed for real property tax purposes as a completed building ready for occupancy, including the following by way of illustration but not limitation; (a) any tax on Lessor’s “right” to rent or
“right” to other income from the Premises or as against Lessor’s business of leasing the Premises; (b) any assessment, tax, fee, levy or charge in substitution, partially or totally, of any assessment, tax, fee, levy or charge
previously included within the definition of real property tax, it being acknowledged by Lessee and Lessor that Proposition 13 was adopted by the voters of the State of California in the June, 1978 election and that assessments, taxes, fees, levies
and charges may be imposed by governmental agencies for such services as fire protection, street, sidewalk and road maintenance, refuse removal and for other governmental services formerly provided without charge to property owners or occupants. It
is the intention of Lessee and Lessor that all such new and increased assessments, taxes, fees, levies and charges be included within the definition of “real property taxes” for the purposes of this Lease; (c) any assessment, tax, fee,
levy or charge allocable to or measured by the area of the premises or other premises in the Building or the rent payable by Lessee hereunder or other lessees of the Building, including, without limitation, any gross receipts tax or excise tax
levied by state, city or federal government, or any political subdivision thereof, with respect to the receipt of such rent, or upon or with respect to the possession, leasing, operation, management, maintenance, alteration, repairs, use or

  

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 occupancy by Lessee of the Premises, or any portion thereof but not on Lessor’s other operations;
(d) any assessment, tax, fee, levy or charge upon this transaction or any document to which Lessee is a party, creating or transferring an interest or an estate in the Premises; and/or (e) any assessment, tax, fee, levy or charge by any governmental
agency related to any transportation plan, fund or system (including assessment districts) instituted within the geographic area of which the Building is a part. 
  
 Notwithstanding the foregoing, if at any time after the Commencement Date, the amount of Real Property Taxes decreases, then
for purposes of all subsequent Lease Years, including the Lease Year in which such decrease in Real Property Taxes occurs, Lessee’s Base Operating Expenses and Real Property Taxes shall be decreased by an amount equal to such decrease in Real
Property Taxes. 
  

	3.	Items Excluded from Operating Expenses. Notwithstanding the provisions of Paragraphs 1 and 2 above to the contrary, “Operating Expenses” and/or
“Real Property Taxes” will not include: (a) Lessor’s federal or state income, franchisee, inheritance or estate taxes; (b) any ground lease rental; (c) costs incurred by Lessor for the repair of damage to the Building to the extent
that Lessor is reimbursed by insurance or condemnation proceeds or by lessees, warrantors or other third persons; (d) depreciation, amortization and interest payments, except as specifically provided herein, and except on materials, tools, supplies
and vendor-type equipment purchased by Lessor to enable Lessor to supply services Lessor might otherwise contract for with a third party, where such depreciation, amortization and interest payments would otherwise have been included in the charge
for such third party’s services, all as determined in accordance with standard accounting practices; (e) brokerage commissions, finders’ fees, attorneys’ fees, space planning costs and other costs incurred by Lessor in leasing or
attempting to lease space in the Building; (f) costs of a capital nature, including, without limitation, capital improvements, capital replacements, capital repairs, capital equipment and capital tools, all as determined in accordance with standard
accounting practices; provided, however, the capital expenditures set forth in Subparagraph 1(n) above will in any event be included in the definition of Operating Expenses; (g) interest, principal, points and fees on debt or amortization on any
mortgage, deed of trust or other debt encumbering the Building or the Building; (h) costs, including permit, license and inspection costs, incurred with respect to the installation of lessee improvements for lessees in the Building (including the
original Lessee Improvements for the Premises), or incurred in renovating or otherwise improving, decorating, painting or redecorating space for lessees or other occupants of the Building, including space planning and interior design costs and fees;
(i) attorneys’ fees and other costs and expenses incurred in connection with negotiations or disputes with present or prospective lessees or other occupants of the Building; provided, however, that Operating Expenses and Real Property Taxes
will include those attorneys’ fees and other costs and expenses incurred in connection with negotiations, disputes or claims relating to items of Operating Expenses and in Real Property Taxes, enforcement of rules and regulations of the
Building, and such other matters relating to the maintenance of standards required of Lessor under the Lease; (j) except for the administrative/management fees described in Subparagraph 1 (i) above, costs of Lessor’s general corporate
overhead, (k) all items and services for which Lessee or any other lessee in the Building reimburses Lessor (others than through operating expenses pass-through provisions); (l) electric power costs for which any lessee directly contracts with the
local public service company; and (m) costs arising from Lessor’s charitable or political contributions. 

  

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 EXHIBIT “F” 
  
 STANDARDS FOR UTILITIES AND SERVICES 
  
 The following standard for utilities and services are in effect. Lessor reserves the right to adopt nondiscriminatory modifications and
additions hereto. 
  
 Subject to the terms and conditions of the Lease and
provided Lessee remains in occupancy of the Premises, Lessor will provide or make available the following utilities and services: 
  
 1. On Monday through Friday, except holidays, from 8:00 a.m. to 6:00 p.m. (and other times at a reasonable hourly additional charge to be fixed by Lessor, the current
cost of after hours HVAC is $45.00 an hour, subject to annual review), ventilate the Premises and furnish air conditioning or heating on such days and hours, when in the reasonable judgment of Lessor it may be required for the comfortable occupancy
of the Premises. The air conditioning system achieves maximum cooling when the window coverings are extended to the full length of the window opening and adjusted to a 45-degree angle. Lessor will not be responsible for room temperatures if Lessee
does not keep all window coverings in the Premises extended to the full length of the window opening and adjusted to a 45-degree angle whenever the system is in operation. Lessee agrees to cooperate fully at all times with Lessor, and to abide by
all reasonable regulations and requirements which Lessor may prescribe for the proper function and protection of said air conditioning system. Lessee agrees not to connect any apparatus, device, conduit or pipe to the chilled and hot water air
conditioning supply lines of the Building. Lessee further agrees that neither Lessee nor its servants, employees, agents, visitors, licensees or contractors shall at any time enter the mechanical installations or facilities of the Building or the
Building or adjust, tamper with, touch or otherwise in any manner affect said installations or facilities. The cost of maintenance and service calls to adjust and regulate the air conditioning system will be charged to Lessee if the need for
maintenance work results from either Lessee’s adjustment of room thermostats or Lessee’s failure to comply with its obligations under this Exhibit, including keeping window coverings extended to the full length of the window opening and
adjusted to a 45 degree angle. Such work will be charged at hourly rates equal to then-current journeyman’s wages for air conditioning mechanics. 
  
 2. Lessor will make available to the Premises, 24 hours per day, seven days a week, electric current as required by the Building standard office lighting and fractional
horsepower office business machines including copiers, personal computer and word processing equipment in an amount not to exceed six (6) watts per square foot per normal business day. Lessee agrees should its electrical installation or electrical
consumption be in excess of the aforesaid quantity or extend beyond normal business hours, to reimburse Lessor monthly for the measured consumption at the average cost per kilowatt-hour charged to the building during the period. If a separate meter
is not installed at Lessee’s cost, such excess cost will be established by an estimate agreed upon by Lessor and Lessee, and if the parties fail to agree, such cost will be established by an independent licensed engineer selected in
Lessor’s reasonable discretion, whose fee shall be shared equally be Lessor and Tenet. Lessee agrees not to use any apparatus or device in, upon or about the Premises (other than standard office business machines, personal computers and work
processing equipment) which may in any way increase the amount of such services usually furnished or supplied to said Premises, and Lessee further agrees not to connect any apparatus or device with wires, conduits or pipes, or other means by which
such services are supplied, for the purpose of using additional or unusual amounts of such services without the written consent of Lessor. Should Lessee use the same to excess, the refusal on part of Lessee to pay upon demand of Lessor the amount
established by Lessor for such excess charge will constitute a breach of the obligation to pay rent under this Lease and will entitle Lessor to the rights therein granted for such breach. Lessee’s use of electric current will never exceed the
capacity of the feeders to the Building, or the risers or wiring installation and Lessees will not install or use or permit the installation of use of any computer or electronic data processing equipment in the Premises (except standard office
business machines, personal computers and word processing equipment) without the prior written consent of Lessor. 
  
 3. Water will be available in public and is for drinking and lavatory purposes only, but if Lessee requires, uses or consumes water for any purpose in addition to
ordinary drinking and lavatory purposes, of which fact Lessee constitutes Lessor to be the sole judge, Lessor may install a water meter and thereby measure Lessee’s water consumption for all purposes. Lessee agrees to pay Lessor for the cost of
the meter and the cost of the installation thereof and throughout the duration of Lessee’s occupancy Lessee will keep said meter and installation equipment in good working order and repair at Lessee’s own cost and expense, in default of
which Lessor may cause such meter and equipment to be replaced or repaired and collect the cost thereof from Lessee. Lessee agrees to pay for water consumed, as shown on such meter, as and when bills and rendered, and on default in making such
payment, Lessor may pay such charges and collect the same from Lessee. Any such costs or expenses incurred, or payments made by Lessor for any of the reasons or purposes hereinabove stated will be deemed to be additional rent payable by Lessee and
collectible by Lessor as such. 
  

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 4. Lessor will provide janitor service to the Premises, provided the same are used exclusively as offices, and are kept
reasonably in order by Lessee, and unless otherwise agreed to by Lessor and Lessee no one other than persons approved by Lessor shall be permitted to enter the Premises for such purposes. If the Premises are not used exclusively as offices, they
will be kept clean and in order by Lessee, at Lessee’s expense, and to the satisfaction of Lessor, and by persons approved by Lessor. Lessee agrees to pay to Lessor the cost of removal of any of Lessee’s refuse and rubbish to the extent
that the same exceeds the refuse and rubbish usually attendant upon the use of the Premises as offices. 
  
 5. Lessor reserves the right to stop service of the elevator, plumbing, ventilation, air conditioning and electrical systems, when necessary, by reason of accident or emergency or for repairs, alterations or
improvements, when in the judgment of Lessor such actions are desirable or necessary to be made, until said repairs, alterations or improvements shall have been completed, and Lessor will have no responsibility or liability for failure to supply
elevator facilities, plumbing, ventilating, air conditioning or electric service, when prevented from so doing by strike or accident or by any cause beyond Lessor’s reasonable control, or by laws, rules, orders, ordinances, directions,
regulations or by reason of the requirements of any federal, state, county or municipal authority or failure of gas, oil or other suitable fuel supply or inability by exercise of reasonable diligence to obtain gas, oil or other suitable fuel supply.
It is expressly understood and agreed that any covenants on Lessor’s part to furnish any services pursuant to any of the terms, covenants, conditions, provisions or agreements of this Lease, or to perform any act or thing for the benefit of
Lessee, will not be deemed breached if Lessor is unable to furnish or perform the same by virtue of a strike of labor trouble or any other cause whatsoever beyond Lessor’s control. 
  

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 “EXHIBIT G” 
  
 ESTOPPEL CERTIFICATE 
 (Sample only, actual Estoppel to be as required by Lender or Others) 
  
 The undersigned, (“Lessee”), hereby certifies to
                                        
         as follows: 
  

	1.	Attached hereto is a true, correct and complete copy of that certain lease dated
                    , 20    , between
                    , Lessor and
                     Lessee (the “Lease”), regarding the premises located 1301 Shoreway Road, Belmont, California 94002 (the
“Premises”). The Lease is now in full force and effect and has not been amended, modified or supplemented, except as set forth in Paragraph 4 below. 

  

	2.	The Term of the Lease commenced on
                            , 20 

  

	3.	The Term of the Lease shall expire on
                              , 20 

  

	4.	The Lease has: (Initial one) 

	 	(    )	not been amended, modified, supplemented, extended, renewed or assigned. 

	 	(    )	been amended, modified, supplemented, extended, renewed or assigned by the following described terms or agreements, copies of which are attached hereto. 

  

	5.	Lessee has accepted and is now in possession of the Premises. 

  

	6.	Lessee and Lessor acknowledge that Lessor’s interest in the Lease will be assigned to              and that
no modification, adjustment, revision or cancellation of the Lease or amendments thereto shall be effective unless written consent of              is obtained, and that until further
notice, payments under the Lease may continue as heretofore. 

  

	7.	The amount of Monthly Base Rent is $ 

  

	8.	The amount of security deposits (if any) is $            . No other security deposits have been made except as follows:

  

	9.	Lessee is paying the full lease rental, which has been paid in full as of the date hereof. No rent or other charges under the Lease have been paid for more than thirty (30) days in
advance of its due date except as follows: 

  

	10.	All work required to be performed by Lessor under the Lease has been completed except as follows: 

  

	11.	There are no defaults on the part of the Lessor or Lessee under the Lease except as follows: 

  

	12.	Neither Lessor nor Lessee has any defense as to its obligations under the Lease and claims no set-off or counterclaim against the other party except as follows:

  

	13.	Lessee has no right to any concession (rental or otherwise) or similar compensation in connection with renting the space it occupies other than as provided in the Lease except as
follows: 

  
 All provisions of the Lease and the amendments thereto
(if any) referred to above are hereby ratified. 
  
 The foregoing certification is
made with the knowledge that                              is about to fund a loan to Lessor or
                                 is about to purchase the Building from Lessor and
that                                  is relying upon the representations herein
made in funding such loan or in purchasing the Building. 
  
 IN WITNESS WHEREOF,
this certificate has been duly executed and delivered by the authorized officers of the undersigned as of                 , 20    .

  
 Lessee: 
 By: 
  
 SAMPLE ONLY 
 [NOT FOR EXECUTION] 
  

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 EXHIBIT “H” 
  
 RULES AND REGULATIONS 
  

	A.	General Rules and Regulations. The following rules and regulations govern the use of the Building and the Building Common Areas. Lessee will be bound by such rules and
regulations and agrees to cause Lessee’s Authorized users, its employees, sublessees, assignees, contractors, suppliers, customers and invitees to observe the same. 

  

	 	1.	Except as specifically provided in the Lease to which these Rules and Regulations are attached, no sign, placard, picture, advertisement, name or notice may be installed or
displayed on any part of the outside or inside of the Building or the Building without the prior written consent of Lessor. Lessor will have the right to remove, at Lessees expense and without notice, any sign installed or displayed in violation of
this rule. All approved signs or lettering on doors and walls are to be printed, painted, affixed or inscribed at the expense of Lessee and under the direction of Lessor by a person or company designated or approved by Lessor.

  

	 	2.	If Lessor reasonably objects in writing to any curtains, blinds, shades, screens or hanging plants or other similar objects attached to or used in connection with any window or door
of the Premises, or placed on any windowsill, which is visible from the exterior of the Premises, Lessee will immediately discontinue such use. Lessee agrees not to place anything against or near glass partitions of doors or windows which may appear
unsightly from outside the Premises including from within any interior common areas. 

  

	 	3.	Lessee will not obstruct any sidewalks, halls, passages, exits, entrances, elevators, escalators, or stairways of the Building. The halls, passages, exits, entrances, elevators and
stairways are not open to the general public, but are open, subject to reasonable regulation, to Lessee’s business invitees. Lessor will in all cases retain the right to control and prevent access thereto of all persons whose presence in the
reasonable judgment of Lessor would be prejudicial of the safety, character, reputation and interest of the Building and its lessees, provided that nothing herein contained will be construed to prevent such access to persons with whom any lessee
normally deals in the ordinary course of its business, unless such persons are engaged in illegal or unlawful activities. No lessee and no employee or invitee of any lessee will go on the roof of the Building without the prior consent of Lessor.

  

	 	4.	Lessee will not obtain for use on the Premises ice, food, food vendors, beverage, towel or other similar services or accept barbering or bootblacking service upon the Premises,
except at such reasonable hours and under such reasonable regulations as may be fixed by Lessor. Lessor expressly reserves the right to absolutely prohibit solicitation, canvassing, distribution of handbills or any other written material, peddling,
sales and displays of products, goods and wares in all portions of the Building except as may be expressly permitted under the Lease. Lessor reserves the right to restrict and regulate the use of the common areas of the Building and Building by
invitees of lessees providing services to lessees on a periodic or daily basis including food and beverage vendors. Such restrictions may include limitations on time, place, manner and duration of access to a lessee’s premises for such
purposes. Without limiting the foregoing, Lessor may require that such parties use service elevators, halls, passageways and stairways for such purposes to preserve access within the Building for lessees and the general public.

  

	 	5.	Lessor reserves the right to require Lessee to periodically provide Lessor with a written list of any and all business invitees which periodically or regularly provide goods and
services at the premises. Lessor reserves the right to preclude any vendors from entering or conducting business within the Building and the Building if such vendors are not listed on lessee’s list of requested vendors.

  

	 	6.	Lessor reserves the right to exclude from the Building between the hours of 6:00 p.m. and 8:00 a.m. the following business day, or such other hours as may be established from time
to time by Lessor, and on Sundays and legal holidays, any person unless that person is known to the person or employee in charge of the Building or has a pass or is properly identified. Lessee will be responsible for all persons for whom it requests
passes and will be liable to Lessor for all acts of such persons. Lessor will not be liable for damages for any error with regard to the admission to or exclusion from the Building of any person. Lessor reserves the right to prevent access to the
Building in case of invasion, mob, riot, public excitement or other commotion by closing the doors or by other appropriate action. 

  

	 	7.	The directory of the Building or the Building will be provided exclusively for the display of the name and location of lessees only and Lessor reserves the right to exclude any
other names therefrom. 

  

	 	8.	 All cleaning and janitorial services for the Building and the Premises will be provided exclusively through Lessor, and except with the written consent of Lessor,
no person or persons other than those approved by Lessor will be employed by Lessee or permitted to enter the Building for the purpose of cleaning the same. Lessee will not cause any unnecessary labor by carelessness or indifference to the good
order and cleanliness of the Premises. 

  

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	 	9.	Lessor will furnish Lessee, free of charge, with two keys to the front door lock of the Premises. Lessor may make a reasonable charge for any additional keys. Lessee shall not make
or have made additional keys, and Lessee shall not alter any lock, install any new additional lock, or bolt on any door of the Premises without the prior consent of Lessor. Lessee, upon the termination of its tenancy, will deliver to Lessor the keys
to all doors which have been furnished to Lessee, and in the event of loss of any keys so furnished, will pay Lessor the reasonable cost therefore. 

  

	 	10.	If Lessee requires telegraphic, telephonic, burglar alarm, satellite dishes, antennae or similar services, it will first obtain Lessor’s approval, and comply with,
Lessor’s reasonable rules and requirements applicable to such services, which may include separate licensing by, and fees paid to, Lessor. 

  

	 	11.	Freight elevator(s) will be available for use by all lessees in the Building, subject to such reasonable scheduling as Lessor, in its discretion, deems appropriate. No equipment,
materials, furniture, packages, supplies, merchandise or other property will be received in the Building or carried in the elevators except between such hours and in such elevators as may be designated by Lessor. Lessee’s initial move in and
subsequent deliveries of bulky times, such as furniture, safes and similar items will, unless others agreed in writing by Lessor, be made during the hours of 6:00 p.m. to 6:00 a.m. or on Saturday or Sunday. Deliveries during normal office hours
shall be limited to normal office supplies and other small items. No deliveries will be made which impede or interfere with other lessees or the operation of the Building. 

  

	 	12.	Lessee will not place a load upon any floor of the Premises, which exceeds the load per square foot which such floor was designed to carry and which is allowed by law. Lessor will
have the right to reasonably prescribe the weight, size and position of all safes, heavy equipment, files, materials, furniture or other property brought into the Building. Heavy objects will, if considered necessary by Lessor, stand on such
platforms as reasonably determined by Lessor to be necessary to properly distribute the weight, which platforms will be provided at Lessee’s expense. Business machines and mechanical equipment belonging to Lessee, which cause noise or vibration
that may be transmitted to the structure of the Building or to any space therein to such a degree as to be reasonably objectionable to any lessees in the Building or Lessor, are to be placed and maintained by Lessee, at Lessee’s expense, on
vibration eliminators or other devises sufficient to eliminate noise or vibration. Lessee will be responsible for all structural engineering required to determine structural load, as well as the expense thereof. The person employed to move such
equipment in or out of the Building must be reasonably acceptable to Lessor. Lessor will not be responsible for loss of, or damage to, any such equipment or other property from any cause, and all damage done to the Building by maintaining or moving
such equipment or other property will be repaired at the expense of Lessee. 

  

	 	13.	Lessee will not use or keep in the Premises any kerosene, gasoline or flammable or combustible fluid or material other than those limited quantities necessary for the operation or
maintenance of office equipment. Lessee will not use or permit to be used in the Premises any foul or noxious gas or substance, or permit or allow the Premises to be occupied or used in a manner reasonably offensive or objectionable to Lessor or
other occupants of the Building by reason of noise, odors or vibrations, nor will Lessee bring into or keep in or about the Premises any birds or animals except for such specially trained animals accompanying persons with physical disabilities,
including but not limited to seeing-eye dogs. 

  

	 	14.	Lessee will not use any method of heating or air conditioning other than that supplied by Lessor without Lessor’s prior written consent. 

  

	 	15.	Lessee will not waste electricity, water or air conditioning; agrees to cooperate fully with Lessor to assure the most effective operation of the Building’s heating and air
conditioning and to comply with any governmental energy-saving rules, laws or regulations of which Lessee has actual notice; and will refrain from attempting to adjust controls. 

  

	 	16.	Lessor reserves the right to change the name and street address of the Building upon sixty (60) days written notice to Lessee. Without the written consent of Lessor, Lessee will not
use the name of the Building or the Building in connection with or in promoting or advertising the business of Lessee except as Lessee’s address. 

  

	 	17.	Lessee will close and lock the doors of its Premises and entirely shut off all water faucets or other water apparatus, and lighting or gas before Lessee and its employees leave the
Premises. Lessee will be responsible for any damage or injuries sustained by other lessees or occupants of the Building or by Lessor for noncompliance with this rule. 

  

	 	18.	The toilet rooms, toilets, urinals, wash bowls and other apparatus will not be used for any purpose other than that for which they were constructed and no foreign substance of any
kind whatsoever shall be thrown therein. The expense of any breakage, stoppage or damage resulting from any violation of this rule will be borne by the lessee who, or whose employees or invitees, break this rule. Cleaning of equipment of any type is
prohibited. Shaving is prohibited. 

  

	 	19.	 Lessee will not sell, or permit the sale at retail of newspapers, magazines, periodicals, theater tickets or any other good or merchandise to the general public in
or on the Premises. Lessee will not use the Premises for any business or activity other than that specifically provided for in this Lease. Lessee will not 

  

 - 29 - 

	 	 
conduct, nor permit to be conducted, either voluntarily or involuntarily, an auction upon the Premises without first having obtained Lessor’s written
consent, which Lessor may withhold in its sole and absolute discretion. 

  

	 	20.	Lessee will not install any radio or television antenna, loudspeaker, or other devices on the roof(s) or exterior walls of the Building or the Building. Lessee will not interfere
with radio or television broadcasting or reception from or in the Building or elsewhere. 

  

	 	21.	Except for the ordinary hanging of pictures and wall decorations, Lessee will not mark, drive nails, scraw or drill into the partitions, woodwork or plaster or in any way deface the
Premises or any part thereof, except in accordance with the provisions of the Lease pertaining to alterations. Lessor reserves the right to direct electricians as to where and how telephone and telegraph wires are to be introduced to the Premises.
Lessee will not cut or bore holes for wires. Lessee will not affix any floor covering to the floor of the Premises in any manner except as approved by Lessor. Lessee shall repair any damage resulting from noncompliance with this rule.

  

	 	22.	Lessee will not install, maintain or operate upon the Premises any vending machines without the written consent of Lessor. 

  

	 	23.	Lessor reserves the right to exclude or expel from the Building any person who, In Lessor’s judgment, is intoxicated or under the influence of liquor or drugs or who is in
violation of any of the Rules and Regulations of the Building. 

  

	 	24.	Lessee will store all its trash and garbage within its Premises or in other facilities provided by Lessor. Lessee will not place in any trash box or receptacle any material which
cannot be disposed of in the ordinary and customary manner of trash and garbage disposal. All garbage and refuse disposal is to be made in accordance with reasonable directions issued from time to time by Lessor. 

  

	 	25.	The Premises will not be used for lodging or for the storage of merchandise held for sale to the general public, or for lodging or for manufacturing of any kind, nor shall the
Premises be used for any improper, immoral or reasonably objectionable purpose. No cooking will be done or permitted on the Premises without Lessor’s consent, except the use by Lessee of Underwriters’ Laboratory approved equipment for
brewing coffee, tea, hot chocolate and similar beverages shall be permitted, and the use of a microwave oven for employees’ use will be permitted, provided that such equipment and use is in accordance with all applicable federal, state, county
and city laws, codes, ordinances, rules and regulations. 

  

	 	26.	Neither Lessee nor any of its employees, agents, customers and invitees may use in any space or in the public halls of the Building or the Building any hand truck except those
equipped with rubber tires and side guards or such other material-handling equipment as Lessor may approve. Lessee will not bring any other vehicles of any kind into the Building. 

  

	 	27.	Lessee agrees to comply with all safety, fire protection and evacuation procedures and regulations established by Lessor or any governmental agency. 

  

	 	28.	Lessee assumes any and all responsibility for protecting its Premises from theft, robbery and pilferage, which includes keeping doors locked and other means of entry to the Premises
closed. 

  

	 	29.	To the extent Lessor reasonably deems it necessary to exercise exclusive control over any portions of the common Areas for the mutual benefit of the lessees in the Building or the
Building, Lessor may do so subject to reasonable, non-discriminatory additional rules and regulations. 

  

	 	30.	Lessor prohibits smoking in the Building. 

  

	 	31.	Lessee’s requirements will be attended to only upon appropriate application to Lessor’s asset management office for the Building by an authorized individual of Lessee or
by such other means provided in the Lease. Employees of Lessor will not perform any work or do anything outside of their regular duties unless under special instructions from Lessor, and no employee of Lessor will admit any person (Lessee of
otherwise) to any office without specific instructions from Lessor. 

  

	 	32.	These Rules and Regulations are in addition to, and will not be construed to in any way modify or amend, in whole or in part, the terms, covenants, agreements and conditions of the
Lease. Lessor may waive any one or more of these Rules and Regulations for the benefit of Lessee of any other lessee, but no such waiver by Lessor will be construed as a waiver of such Rules and Regulations in favor of Lessee or any other lessee,
nor prevent Lessor from thereafter enforcing any such Rules and Regulations against any or all of the lessees of the Building. 

  

	 	33.	Lessor reserves the right to make such other and reasonable and non-discriminatory Rules and Regulations as, in its judgment, may from time to time be needed for safety and
security, for care and cleanliness of the Building and for the preservation of good order therein. Lessee agrees to abide by all such Rules and Regulations herein above stated and any additional reasonable and non-discriminatory rules and
regulations which are adopted and of which Lessee receives prior notice. Lessee is responsible for the observance of all the foregoing rules by Lessee’s employees, agents, clients, customers, invitees and guests. 

  

 - 30 - 

	B.	Parking Rules and Regulations. The following rules and regulations govern the use of the parking facilities which serve the Building. Lessee will be bound by
such rules and regulations and agrees to cause its employees, sublessees, assignees, contractors, suppliers, customers and invitees to observe the same: 

  

	 	1.	Lessee will not permit or allow any vehicles that belong to or are controlled by Lessee or Lessee’s employees, sublessees, customers or invitees to be loaded, unloaded or
parked in areas other than those designated by Lessor for such activities. No vehicles are to be left in the parking areas overnight and no vehicles are to be parked in the parking areas other than normally sized passenger automobiles, motorcycles
and pick-up trucks. No extended term storage of vehicles is permitted. 

  

	 	2.	Vehicles must be parked entirely within painted stall lines of a single parking stall. 

  

	 	3.	All directional signs and arrows must be observed. 

  

	 	4.	The speed limit within all parking areas shall be five (5) miles per hour. 

  

	 	5.	Parking is prohibited; (a) in areas not striped for parking; (b) in aisles or on ramps; (c) where “no parking” signs are posted; (d) in cross-hatched areas; and (e) in
such other areas as may be designated from time to time by Lessor or Lessor’s parking operator. 

  

	 	6.	Lessor reserves the right, without cost or liability to Lessor, to tow any vehicle if such vehicle’s audio theft alarm system remains engaged for an unreasonable period of
time. 

  

	 	7.	Washing, waxing, cleaning or servicing of any vehicle in any area not specifically reserved for such purpose is prohibited. 

  

	 	8.	Lessor may refuse to permit any person to park in the parking facilities who violates these rules with unreasonable frequency, and any violation of these rules shall subject the
violator’s car to removal, at such car owner’s expense. Lessee agrees to use its best efforts to acquaint its employees, sublessees, assignees, contractors, suppliers, customers and invitees with these parking provisions, rules and
regulations. 

  

	 	9.	All damage or loss claimed to be the responsibility of Lessor must be reported, itemized in writing and delivered to the management office located within the Building within ten
(10) business days after any claimed damage or loss occurs. Any claim not so made is waived. Lessor is not responsible for damage by water or fire, or for the acts or omissions of others, or for articles left in vehicles. In any event, the total
liability of Lessor, if any, is limited to Two Hundred Fifty Dollars ($250.00) for all damages or loss to any car. Lessor is not responsible for loss of use. 

  

	 	10.	Lessor reserves the right, without cost or liability to Lessor, to tow any vehicles which are used or parked in violation of these rules and regulations. 

 

	 	11.	Parking will be free of charge for the initial Term of the Lease. 

  

	C.	Lessor reserves the right from time to time to modify and/or adopt such other reasonable and non-discriminatory rules and regulations for the parking facilities as it deems
reasonably necessary for the operation of the parking facilities. 

  

 - 31 - 

 EXHIBIT “I” 
  
 HAZARDOUS MATERIALS DISCLOSURE CERTIFICATE 
  
 Your cooperation in this matter is appreciated. Initially, the information provided by you in the Hazardous Materials Disclosure Certificate
is necessary for the Lessor (identified below) to evaluate and finalize a lease agreement with you as the Lessee. After a lease agreement is signed by you and the Lessor (the “Lease Agreement”), on an annual basis in accordance with the
provisions of Section 29 of the signed Lease Agreement, you are to provide an update to the information initially provided by you in this certificate. The information contained in the initial Hazardous Materials Disclosure Certificate and each
annual certificate provided by you thereafter will be maintained in confidentiality by Lessor subject to release and disclosure as required by (i) any lenders and owners and their respective environmental consultants, (ii) any prospective
purchaser(s) of all or any portion of the property on which the Premises are located, (iii) Lessor to defend itself or its lenders, partners or representatives against any claim or demand, and (iv) any laws, rules, regulations, orders, decrees, or
ordinances, including, without limitation, court orders or subpoenas. Any and all capitalized terms used herein, which are not otherwise defined herein, shall have the same meaning ascribed to such term in the signed Lease Agreement. Any questions
regarding this certificate should be directed to, and when completed, the certificate should be delivered to: 
  

			
	 Lessor:
	 	 F & S Properties, LLC

	 	 	 250A Twin Dolphin Drive

	 	 	 Redwood City, CA 94065

	 	 	 Phone: (650) 622-2801

  
 Name of (Prospective) Tenant:                               
                                        
                                        
                                        
        
  
 Mailing Address:                                  
                                        
                                        
                                        
                              
  
                                       
                                        
                                        
                                        
                                        
                    
  
 Contact
Person:                                       
                                     Telephone
 Number:                                      
                                 
  
 Address of (Prospective) Premises:                              
                                        
                                        
                                       
 
  
 Length of (Prospective) Initial
Term:                                       
                                        
                                        
                            
  

	1.	GENERAL INFORMATION: 

  
 Describe the initial proposed operations to take place in, on, or about the Premises, including, without limitation, principal products
processed, manufactured or assembled service and activities to be provided otherwise conducted. Existing tenants should describe any proposed changes to on-going operations. 
  
                                       
                                        
                                        
                                        
                                        
           
  
                                       
                                        
                                        
                                        
                                        
           
  

	2.	USE, STORAGE AND DISPOSAL OF HAZARDOUS MATERIALS 

  

	 	2.1	Will any Hazardous Materials be used, generated, stored or disposed of in, on, or about the Premises? Existing tenants should described any Hazardous Materials which continue to be
used, generated, stored or disposed of in, on or about the Premises. 

  

									
	 	 	  Wastes:	  	Yes  	 ̈	 	No  	x
	 	 	  Chemical Products:	  	Yes  	 ̈	 	No  	x
	 	 	  Other:	  	Yes  	 ̈	 	No  	x

  

	 	    	If Yes is marked, please
explain:                                      
                                        
                                        
                  

  
                                       
                                        
                                        
                                        
                                        

  
  

	 	2.2	If Yes is marked in Section 2.1 attach a list of any Hazardous Materials to be used, general, stored or disposed of in, on or about the Premises, Including the applicable hazard
class and an estimate of the quantities of such Hazardous Materials at any given time, estimated annual throughput, the proposed location(s) and method of storage (excluding nominal amounts of ordinary household cleaners and janitorial supplies
which are not regulated by any Environmental Laws); and the proposed location(s) and method of disposal for each Hazardous Material, including, the estimated frequency, and the proposed contractors or subcontractors. Existing tenants should attach a
list setting forth the information requested above and such list should include actual data from ongoing operations and the identification of any variations in such information from the prior year’s certificate. 

  

 - 32 - 

					
	 3.      
	  	 STORAGETANKS AND SUMPS

			
	 	  	3.1	  	Is any above or belowground storage of gasoline, diesel, petroleum, or other Hazardous Materials in tanks or sumps proposed in, on or about the Premises? Existing tenants should describe any
such actual or proposed activities.
			
	 	  	 	  	Yes   ̈                     No   ̈
			
	 	  	 	  	 If Yes, please
explain:                                      
                                        
                                        
                                     
  
                                       
                                        
                                        
                                        
                                       
 
  
                                       
                                        
                                        
                                        
                                       
 

		
	 4.
	  	WASTE MANAGEMENT
			
	 	  	4.1	  	Has your company been issued an EPA Hazardous Waste Generator I.D. Number? Existing tenants should describe any additional identification numbers issued since the previous
certificate.
			
	 	  	 	  	Yes   ̈                     No  x
			
	 	  	4.2	  	Has your company filed a biennial or quarterly report as a hazardous waste generator? Existing tenants should describe any new reports filed.
			
	 	  	 	  	Yes   ̈                     No  x
			
	 	  	 	  	If Yes, attach a copy of the most recent report filed.
		
	 5.      
	  	WASTEWATER TREATMENT AND DISCHARGE
			
	 	  	5.1	  	Will your company discharge wastewater or other wastes to:
			
	 	  	 	  	Storm drain?    ̈                     Sewer?   ̈
			
	 	  	 	  	Surface water?    ̈                 No wastewater or other wastes discharged   ̈
			
	 	  	 	  	Existing tenants should indicate any actual discharges. If so, describe the nature of any proposed or actual discharge(s).
			
	 	  	 	  	
  
  

			
	 	  	5.2	  	Will any such wastewater or waste be treated before discharge?
			
	 	  	 	  	Yes   ̈                     No   ̈
			
	 	  	 	  	If Yes, describe the type of treatment proposed to be conducted. Existing tenants should describe the actual treatment conducted.
		
	 6.      
	  	AIR DISCHARGES
			
	 	  	6.1	  	Do you plan for any air filtration systems or stacks to be used in your company’s operations in, on, or about the Premises that will discharge into the air, and will such air emissions be
monitored? Existing tenants should indicate whether or not there are any such air filtration systems or stacks in use in, on, or about the Premises which discharge into the air and whether such air emissions are being monitored.
			
	 	  	 	  	Yes   ̈                     No  x
			
	 	  	 	  	 If Yes, please
describe:                                      
                                        
                                        
                                   
  
                                       
                                        
                                        
                                        
                                       
 
  
                                       
                                        
                                        
                                        
                                       
 

			
	 	  	6.2	  	Do you propose to operate any of the following types of equipment, or any other equipment requiring an air emissions permit? Existing tenants should specify any such equipment being operated in,
on or about the Premises.
			
	 	  	 	  	Spray booth(s):   ̈                     Incinerator(s-):-   ̈
			
	 	  	 	  	Dip tank(s):   ̈                          Other (Please describe):   ̈
			
	 	  	 	  	Drying oven(s):   ̈                    No Equipment Requiring Air Permits:   ̈
			
	 	  	 	  	 If Yes, please
describe:                                      
                                        
                                        
                                   
  
                                       
                                        
                                        
                                        
                                       
 
  
                                       
                                        
                                        
                                        
                                       
 

  

 - 33 - 

					
		
	 7.
	 	HAZARDOUS MATERIALS DISCLOSURES
			
	 	 	7.1	    	Has your company prepared or will it be required to prepare a Hazardous Materials management plan (“Management Plan”) pursuant to Fire Department or other governmental or regulatory
agencies requirements? Existing tenants should indicate whether or not a Management Plan is required and has been prepared.
			
	 	 	 	    	Yes   ̈                     No  x
			
	 	 	 	    	If Yes, attach a copy of the Management Plan. Existing tenants should attach a copy of any required updates to the Management Plan.
			
	 	 	7.2	    	Are any of the Hazardous Materials, and in particular chemicals, proposed to be used in your operations in, on or about the Premises regulated under Proposition 65? Existing tenants should
indicate whether or not there are any new Hazardous Materials being so used which are regulated under Proposition 65.
			
	 	 	 	    	Yes   ̈                     No  x
			
	 	 	 	    	 If Yes, please
explain:                                      
                                        
                                        
                                     
  
                                       
                                        
                                        
                                        
                                       
 
  
                                       
                                        
                                        
                                        
                                       
 

		
	 8.      
	 	ENFORCEMENT ACTIONS AND COMPLAINTS
			
	 	 	8.1	    	With respect to Hazardous Materials or Environmental Laws, has your company ever been subject to any agency enforcement actions, administrative orders, or consent decrees or has your company
received requests for information, notice or demand letters, or any other inquires regarding its operations? Existing tenants should indicate whether or not any such actions, orders or decrees have been, or are in the process or being, undertaken or
if any such requests have been received.
			
	 	 	 	    	Yes   ̈                     No  x
			
	 	 	 	    	If Yes, describe the actions, orders or decrees and any continuing compliance obligations imposed as a result of these actions, orders or decrees and also describe any requests, notices or
demands, and attach a copy of all such documents. Existing tenants should describe and attach a copy of any new actions, orders, decrees, requests, notices or demands not already delivered to Lessor pursuant to the provisions of Section 29 of the
signed Lease Agreement.
	 	 	 	    	  
                                       
                                        
                                        
                                        
                                       
 
  
                                       
                                        
                                        
                                        
                                       
 

			
	 	 	8.2	    	Have there ever been, or are there now pending, any lawsuits against your company regarding any environmental or health and safety concern?
			
	 	 	 	    	Yes   ̈                     No  x
			
	 	 	 	    	If yes, describe any such lawsuits and attach copies of the complaint(s), cross-complaint(s), pleadings and all other documents related thereto as requested by Landlord. Existing tenants should
described and attach a copy of any new complaint(s), cross-complaint(s), pleadings and other related documents not already delivered to Lessor pursuant to the provisions of Section 29 of the signed Lease Agreement.
			
	 	 	 	    	  
                                       
                                        
                                        
                                        
                                       
 
  
                                       
                                        
                                        
                                        
                                       
 

  

 - 34 - 

					
			
	 	  	8.3	  	Have there been any problems or complaints from adjacent tenants, owners or other neighbors at your company’s current facility with regard to environmental or health and safety concerns?
Existing tenants should indicate whether or not there have been any such problems or complaints from adjacent tenants, owners or other neighbors at, about or near the Premises.
			
	 	  	 	  	Yes   ̈                     No  x
			
	 	  	 	  	If yes, please describe. Existing tenants should describe any such problems or complaints not already disclosed to Lessor under the provisions of the signed Lease Agreement.
			
	 	  	 	  	                                       
                                        
                                        
                                        
                                       
 
  
                                       
                                        
                                        
                                        
                                       
 

		
	 9.
	  	PERMITS AND LICENSES
			
	 	  	9.1	  	Attach copies of all Hazardous Materials permits and licenses issued to your company with respect to its proposed operations in, on or about the Premises, including, without limitation, any
wastewater discharge permits, air emissions permits, and use permits or approvals. Existing tenants should attach copies of any new permits and licenses as well as any renewals of permits or licenses previously issued.

  
 The undersigned hereby acknowledges
and agrees that (A) this Hazardous Materials Disclosure Certificate is being delivered in connection with, and as required by, Lessor in connection with the evaluation and finalization of a Lease Agreement and will be attached thereto as an exhibit;
(B) that this Hazardous Materials Disclosure Certificate is being delivered in accordance with, and as required by, the provisions of Section 29 of the Lease Agreement; and (C) that Tenant/Lessee shall have and retain full and complete
responsibility and liability with respect to any of the Hazardous Materials disclosed in the HazMat Certificate notwithstanding Lessor’s/Tenant’s receipt and/or approval of such certificate. Lessee further agrees that none of the following
described acts or events shall be construed or otherwise interpreted as either (a) excusing, diminishing or otherwise limiting Lessee from the requirement to fully and faithfully perform its obligations under the Lease with respect to Hazardous
Materials, including, without limitation, any duty on Lessor to investigate or otherwise verify the accuracy of the representations and statements made therein or to ensure that Lessee is in compliance with all Environmental Laws; (i) the delivery
of such certificate, (ii) Lessor’s review and approval of such certificate, (iii) Lessor’s failure to obtain such certificate from Lessee at any time, or (iv) Lessor’s actual or constructive knowledge of the types and quantities of
Hazardous Materials being used, stored, generated, disposed of or transported on or about the Premises by Lessee or Lessee’s Representatives. Notwithstanding the foregoing or anything to the contrary contained herein, the undersigned
acknowledges and agrees that Lessor and it partners, lenders and representatives may, and will rely upon the statements, representations, warranties, and certifications made herein and the truthfulness thereof, of the Lease Agreement. 
  
 I (print name) DONALD J. SANTEL acting with full authority to bind the (proposed)
Lessee and on behalf of the (proposed) Lessee, certify, represent and warrant that the information contained in this certificate is true and correct. 
  
 (PROSPECTIVE) TENANT: 
  

			
	 By:
	 	 /s/ Donald J. Santel

	 Print Name:
	 	 DONALD J. SANTEL

	 Title:
	 	 COO

	 Date:
	 	 1/9/03

  

 - 35 -

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