Document:

Exhibit 10.18

Samaritan Pharmaceuticals, Inc. and Samaritan Pharmaceuticals Ireland Ltd.,
agreement with Pharmaplaz Ltd., Research, Development and Commercialization
Collaboration Agreement Supplement

This Supplement Agreement ("Licensing Collaboration") between Samaritan
Pharmaceuticals, Inc. and Samaritan Pharmaceuticals Ireland Ltd. ("Samaritan")
with Pharmaplaz Ltd. ("Pharmaplaz") is made and entered into as of the effective
date below. Samaritan and Pharmaplaz have entered into this agreement for the
purpose of allocating between the parties certain rights relating to an SP-01A
project to be carried out by Pharmaplaz and Samaritan (hereinafter referred to
as the "PARTIES").

1. Licensing Collaboration Samaritan hereby issues a collaboration license to
Pharmaplaz for SP-01A (an HIV oral entry inhibitor) which includes all pending
or issued patent rights, technology rights, technical know how, and rights to
inventions made by Samaritan.

2. Financial and Contractual Terms
<TABLE>
<CAPTION>

a. Upon execution of this Licensing Collaboration, Pharmaplaz agrees to pay Samaritan as follows:

<S>     <C>                         <C> <C>                                      <C>
Payment 1                     March 16, 2007                                   US$1,400,000
-------------------------     --------------------------------------------     -------------------------------

Payment 2                     September 16, 2007                               US$8,600,000
-------------------------     --------------------------------------------     -------------------------------
</TABLE>

b. Samaritan will be responsible for all future patent expenses, including
filing, prosecution, and enforcement expenses.

c. The term of Licensing Collaboration is the longer duration of the patent
rights or technology rights.

d. Pharmaplaz will pay for and be responsible for future research and
development to bring the technology to market. Samaritan has no remaining
obligation or performance for future research and development. The $10,000,000
payment is non-refundable. If requested by Pharmaplaz, Samaritan will perform
sponsored research regarding SP-01A or participate as Principal Investigators in
applications for NIH grants, or other grants applications to advance SP-01A, at
Pharmaplaz cost.

e. Samaritan and Pharmaplaz will split 50/50 all revenues stemming from SP-01A.

3. Closing Conditions - This Licensing Collaboration becomes binding on both
parties following the remittance of the US$1,400,000 on March 16, 2007.

4. Press Release - All press releases and other public announcements and
announcements to customers, suppliers, license or regulatory agencies, or
employees regarding this transaction will be prepared jointly by Samaritan and
Pharmaplaz. Samaritan retains the right to make such disclosures as may be
required by applicable law.

5. Binding Effect, Counterparts, Miscellaneous - This supplement agreement is
intended to be a binding agreement between the parties hereto and is intended to
be an expression of entire mutual understandings and agreement. Any
modifications to this supplement agreement shall be made in writing and agreed
to by both parties in writing.

6. Effective Date. The effective date of this supplement agreement is March 9,
2007.

Agreed:

Pharmaplaz

By:/s/Michael Macken   Date: May 16, 2007
--------------------
Micheal Macken, CEO

Samaritan Pharmaceuticals, Inc.

By:/s/Janet Greeson  Date: May 16, 2007
-------------------
Janet Greeson, CEO

Samaritan Pharmaceuticals Ireland, Ltd.

By:/s/Eugene Boyle  Date: May 16, 2007
-------------------
Eugene Boyle, CFOEXHIBIT 10.1

THIS AGREEMENT IS made the               day of April 30, 2007

BETWEEN

1.   ZONE4PLAY, INC a company incorporated under the laws of the state of
     Delaware, USA, having its registered office at 103 Foulk Road, Suite 202,
     Wilmington, Delaware (ZONE)

2.   TWO WAY LIMITED (ABN 28 007 424 777) of Level 3, 55 Pyrmont Bridge Road,
     Pyrmont, NSW 2009, Australia (TWO WAY)

     (each a PARTY and together PARTIES)

PRELIMINARY

(A)  Zone and Two Way (under its then name Two Way TV Australia Limited) entered
     into a written agreement on 17 August 2005 (THE EXCLUSIVE DISTRIBUTION
     AGREEMENT)

(B)  Zone and Two Way have agreed to vary the Exclusive Distribution Agreement
     on and subject to the terms of this Agreement.

1.   DEFINITIONS AND INTERPRETATION

     1.1  Words defined in the Exclusive Distribution Agreement will have the
          same meaning when used in this agreement.

     1.2  The clause headings are inserted for ease of reference only and do not
          affect the construction of this agreement.

     1.3  Words denoting the singular include the plural and vice versa; words
          denoting any gender include all genders; and words denoting persons
          include corporations, partnerships, other unincorporated bodies and
          all other legal entities and vice versa.

2.   EXCLUSIVE/NON-EXCLUSIVE LICENCE

     2.1  The Licence referred to in clauses 2.1 and 2.3 of the Exclusive
          Distribution Agreement shall be exclusive for the period 1 June 2005
          to 30 June 2008 and non-exclusive for the period 1 July 2008 to 31 May
          2010. For the avoidance of doubt, it is clarified that such exclusive
          license shall not limit the rights of Zone, by itself or by permitting
          third parties, to exploit or use its Intellectual Property in
          connection with Play for Fun and Play for Real Products on the
          internet, provided however that Zone are not permitted to make
          available Product to mobile phone users in the Territory via the
          internet without the permission of Two Way.

                                       1
<PAGE>

     2.2  For the avoidance of doubt "non-exclusive" means that Zone is entitled
          by itself or by permitting third parties to exploit or use its
          Intellectual Property in connection with Play for Fun and Play for
          Real Products in Australasia without the permission of Two Way from 1
          July 2008.

     2.3  Zone and Two Way confirm that the Play for Fun and Play for Real
          Products covered under the Licence include all of the applications
          described in the Appendices to the Agreement (totalling 77 pages)
          which were initialled by both parties and attached to the Term Sheet
          dated 23 May 2005 signed by both parties.

3.   INSTALLATION

     Clauses 3.3 and 3.8 of the Exclusive Distribution Agreement shall be varied
     to require Two Way to produce evidence of written agreements with Operators
     before Zone shall be obliged to supply Two Way with the tools, background
     technology and the completed solution referred to in clauses 3.3 and 3.8
     respectively.

4.   FEES

     The Fixed Licence Fees and the First and Last Matching Rights Fee payable
     under clause 5 of the Exclusive Distribution Agreement shall be varied as
     follows:

     4.1  Clause 5.1(a) - insert after "Fixed Licence Fee" the words "for the
          period up to 30 June 2008".

     4.2  Clause 5.5(a) - insert after "Fixed Licence Fee" the words "for the
          period up to 30 June 2008".

     4.3  Clause 5.6 is deleted.

     4.4  Clause 5.9(a) - insert after "First and Last Matching Rights Fee" the
          words "for the period up to 30 June 2008".

     4.5  In accordance with the payment terms under the Exclusive Distribution
          Agreement, as varied by this Agreement, Two Way will pay a total fee
          of $525,000 to Zone for the period from the date of execution of this
          Agreement until 30 June 2008, with the payments to be payable on the
          following dates:

          US$175,000 within seven days of the date of this Agreement;
          US$87,500 on 1 July 2007;
          US$87,500 on 1 October 2007;
          US$87,500 on 1 January 2008; and
          US$87,500 on 1 April 2008.

                                       2
<PAGE>

5.   OPTIONS

     Clauses 8.2 to 8.4 of the Exclusive Distribution Agreement shall be
     deleted.

6.   FULL AND FINAL SETTLEMENT

     Zone hereby waives all and any claims against Two Way and Two Way hereby
     waives all and any claims against Zone in respect of all causes of action
     which have or may have accrued to date under the Exclusive Distribution
     Agreement and/or in respect of the performance or alleged breach of either
     parties obligations contained in the Exclusive Distribution Agreement in
     particular those matters referred to in Two Way's letters of 23 January and
     7 February 2007 to Zone and Zone's letter of 31 January 2007 to Two Way to
     the intent that the execution of this Agreement shall be in full and final
     settlement thereof and neither party will allege any breach against the
     other party in respect of the same causes of action now and whenever
     arising at any time in the future.

7.   AUTHORITY

     The persons executing this Agreement have been duly authorised and
     empowered to do so on behalf of the respective parties hereto.

8.   WAIVERS

     The failure of either party at any time to require performance of any
     provision of this Agreement shall not affect its right to enforce such
     provision at a later time.

9.   JURISDICTION

     This Agreement shall be governed by and construed in accordance with the
     laws of England. The parties submit to and agree that any dispute arising
     out of or in any way connected with this Agreement shall be submitted to
     the exclusive jurisdiction of the English courts.

10.  ENTIRE AGREEMENT

     This Agreement represents the entire understanding of Zone and Two Way on
     the subject matter hereof and sets aside all previous agreements,
     negotiations and discussions between the parties. This Agreement may not be
     modified or amended except by written agreement signed by the duly
     authorised representatives of each of the parties hereto.

                                       3
<PAGE>

11.  CONTRACTS (RIGHTS OF THIRD PARTIES) ACT 1999

     A person who is not a party to this Agreement shall not have any rights
     under or be able to enforce this Agreement by virtue of the Contracts
     (Rights of Third Parties) Act 1999.

IN WITNESS whereof this Agreement has been executed by the parties hereto as a
deed and is intended to be and is hereby delivered on the date first above
written

Signed by                           )
for and on behalf of                )
ZONE4PLAY, INC                              /s/ Shimon Citron
                                            ---------------------------
                                            Shimon Citron, Director

Signed by                           )
for and on behalf of                )
TWO WAY LIMITED                             /s/ Chris Grant-Foster
                                            ---------------------------
                                            Chris Grant-Foster

                                       4

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00123-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00123-of-00352.parquet"}]]