Document:

Employee Stock Purchase Plan

 Exhibit 10.4 
 SENORX, INC. 
 EMPLOYEE STOCK PURCHASE PLAN 
 1. Purpose. The purpose of the Plan is to provide employees of the Company and its Designated Subsidiaries with an opportunity to purchase Common
Stock of the Company through accumulated payroll deductions. It is the intention of the Company to have the Plan qualify as an “Employee Stock Purchase Plan” under Section 423 of the Code. The provisions of the Plan, accordingly,
shall be construed so as to extend and limit participation in a uniform and nondiscriminatory basis consistent with the requirements of Section 423. 
 2. Definitions. 
 (a) “Administrator” shall mean the Board or any
Committee designated by the Board to administer the plan pursuant to Section 14. 
 (b) “Board” shall
mean the Board of Directors of the Company. 
 (c) “Change in Control” means the occurrence of any of the
following events: 
 (i) Any “person” (as such term is used in Sections 13(d) and 14(d) of the Exchange Act) becomes
the “beneficial owner” (as defined in Rule 13d-3 of the Exchange Act), directly or indirectly, of securities of the Company representing fifty percent (50%) or more of the total voting power represented by the Company’s then
outstanding voting securities; or 
 (ii) The consummation of the sale or disposition by the Company of all or substantially
all of the Company’s assets; or 
 (iii) A change in the composition of the Board occurring within a two-year period, as
a result of which fewer than a majority of the directors are Incumbent Directors. “Incumbent Directors” means directors who either (A) are Directors as of the effective date of the Plan, or (B) are elected, or nominated for
election, to the Board with the affirmative votes of at least a majority of the Directors at the time of such election or nomination (but will not include an individual whose election or nomination is in connection with an actual or threatened proxy
contest relating to the election of directors to the Company); or 
 (iv) The consummation of a merger or consolidation of the
Company with any other corporation, other than a merger or consolidation which would result in the voting securities of the Company outstanding immediately prior thereto continuing to represent (either by remaining outstanding or by being converted
into voting securities of the surviving entity or its parent) at least fifty percent (50%) of the total voting power represented by the voting securities of the Company or such surviving entity or its parent outstanding immediately after such
merger or consolidation. 
 (d) “Code” shall mean the Internal Revenue Code of 1986, as amended. 

 (e) “Committee” means a committee of the Board appointed in accordance
with Section 14 hereof. 
 (f) “Common Stock” shall mean the common stock of the Company. 
 (g) “Company” shall mean SenoRx, Inc., a Delaware corporation. 
 (h) “Compensation” shall mean all base straight time gross earnings, commissions, overtime and shift premium, but
exclusive of payments for incentive compensation, bonuses and other compensation. 
 (i) “Designated
Subsidiary” shall mean any Subsidiary selected by the Administrator as eligible to participate in the Plan. 
 (j)
“Director” shall mean a member of the Board. 
 (k) “Eligible Employee” shall mean any
individual who is a common law employee of the Company or any Designated Subsidiary and whose customary employment with the Company or Designated Subsidiary is at least twenty (20) hours per week and more than five (5) months in any
calendar year. For purposes of the Plan, the employment relationship shall be treated as continuing intact while the individual is on sick leave or other leave of absence approved by the Company. Where the period of leave exceeds 90 days and the
individual’s right to reemployment is not guaranteed either by statute or by contract, the employment relationship shall be deemed to have terminated on the 91st day of such leave. 
 (l) “Exchange Act” shall mean the Securities Exchange Act of 1934, as amended. 
 (m) “Exercise Date” shall mean the first Trading Day on or after March 31st and September 30th of each year. The first Exercise Date under the Plan shall be March 31, 2007. 
 (n) “Fair
Market Value” shall mean, as of any date and unless the Administrator determines otherwise, the value of Common Stock determined as follows: 
 (i) If the Common Stock is listed on any established stock exchange or a national market system, including without limitation the Nasdaq National Market, its Fair Market Value shall be the closing sales price for such
stock (or the closing bid, if no sales were reported) as quoted on such exchange or system on the date of determination, as reported in The Wall Street Journal or such other source as the Board deems reliable; 
 (ii) If the Common Stock is regularly quoted by a recognized securities dealer but selling prices are not reported, its Fair Market Value
shall be the mean of the closing bid and asked prices for the Common Stock on the date of determination, as reported in The Wall Street Journal or such other source as the Board deems reliable; 
 (iii) In the absence of an established market for the Common Stock, the Fair Market Value thereof shall be determined in good faith by the
Board; or 
  

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 (iv) For purposes of the Offering Date of the first Offering Period under the Plan, the
Fair Market Value shall be the initial price to the public as set forth in the final prospectus included within the registration statement on Form S-1 filed with the Securities and Exchange Commission for the initial public offering of the
Company’s Common Stock (the “Registration Statement”). 
 (o) “Fiscal Year” means the fiscal
year of the Company. 
 (p) “Offering Date” shall mean the first Trading Day of each Offering Period.

 (q) “Offering Periods” shall mean the periods of approximately six (6) months during which an option
granted pursuant to the Plan may be exercised, commencing on the first Trading Day on or after April 1st and
October 1st of each year and terminating on the first Trading Day on or after the subsequent Offering Period
commencement date approximately six months later; provided, however, that the first Offering Period under the Plan shall commence with the first Trading Day on or after the date on which the Securities and Exchange Commission declares the
Company’s registration statement on Form S-1 effective and end on the first Trading Day on or after March 31, 2007 and the second Offering Period under the Plan shall commence with the first Trading Day on or after April 1, 2007. The
duration and timing of Offering Periods may be changed pursuant to Section 4 of this Plan. 
 (r) “Plan”
shall mean this SenoRx, Inc. Employee Stock Purchase Plan. 
 (s) “Purchase Price” shall mean 85% of the Fair
Market Value of a share of Common Stock on the Exercise Date; provided however, that the Purchase Price may be determined for subsequent Offering Periods by the Administrator subject to compliance with Section 423 of the Code (or any successor
rule or provision or any other applicable law, regulation or stock exchange rule) or pursuant to Section 20. 
 (t)
“Subsidiary” shall mean a “subsidiary corporation,” whether now or hereafter existing, as defined in Section 424(f) of the Code. 
 (u) “Trading Day” shall mean a day on which the national stock exchange upon which the Company Common Stock is listed is
open for trading. 
 3. Eligibility. 
 (a) First Offering Period. Any individual who is an Eligible Employee immediately prior to the first Offering Period shall be automatically enrolled in the first Offering Period. 
 (b) Subsequent Offering Periods. Any Eligible Employee on a given Offering Date shall be eligible to participate in the Plan.

 (c) Limitations. Any provisions of the Plan to the contrary notwithstanding, no Eligible Employee shall be granted
an option under the Plan (i) to the extent that, immediately after the grant, such Eligible Employee (or any other person whose stock would be attributed to such Eligible Employee pursuant to Section 424(d) of the Code) would own capital
stock of the Company 

  

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and/or hold outstanding options to purchase such stock possessing five percent (5%) or more of the total combined voting power or value of all classes
of the capital stock of the Company or of any Subsidiary, or (ii) to the extent that his or her rights to purchase stock under all employee stock purchase plans of the Company and its subsidiaries accrues at a rate which exceeds Twenty-Five
Thousand Dollars ($25,000) worth of stock (determined at the fair market value of the shares at the time such option is granted) for each calendar year in which such option is outstanding at any time. 
 4. Offering Periods. The Plan shall be implemented by consecutive Offering Periods with a new Offering Period commencing on the first Trading Day
on or after April 1st and October 1st each year, or on such other date as the Board shall determine; provided, however, that the first Offering Period under the Plan shall commence with the first
Trading Day on or after the date upon which the Company’s Registration Statement is declared effective by the Securities and Exchange Commission and end on the first Trading Day on or after March 31, 2007. The Board shall have the power to
change the duration of Offering Periods (including the commencement dates thereof) with respect to future offerings without stockholder approval if such change is announced prior to the scheduled beginning of the first Offering Period to be affected
thereafter. 
 5. Participation. 
 (a) First Offering Period. An Eligible Employee shall be entitled to participate in the first Offering Period only if such individual submits a subscription agreement authorizing payroll deductions in a form
determined by the Administrator (which may be similar to the form attached hereto as Exhibit A) to the Company’s designated plan administrator (i) no earlier than the effective date of the Form S-8 registration statement with
respect to the issuance of Common Stock under this Plan and (ii) no later than twenty (20) business days following the effective date of such S-8 registration statement (the “Enrollment Window”). An Eligible
Employee’s failure to submit the subscription agreement during the Enrollment Window shall result in the automatic termination of such individual’s participation in the Offering Period. 
 (b) Subsequent Offering Periods. An Eligible Employee may become a participant in the Plan by completing a subscription agreement
in a form determined by the Administrator (which may be similar to the form attached hereto as Exhibit A) and filing it with the Company’s designated Plan administrator prior to the applicable Offering Date. 
 6. Payroll Deductions. 
 (a) At the time a participant files his or her subscription agreement, he or she shall elect to have payroll deductions made on each pay day during the Offering Period in an amount not exceeding 10% of the Compensation which he or she
receives on each pay day during the Offering Period; provided, however, that should a pay day occur on an Exercise Date, a participant shall have the payroll deductions made on such day applied to his or her account under the new Offering Period. A
participant’s subscription agreement shall remain in effect for successive Offering Periods unless terminated as provided in Section 10 hereof. 
 (b) Payroll deductions for a participant shall commence on the first pay day following the Offering Date and shall end on the last pay day in the Offering Period to which such authorization is applicable, unless
sooner terminated by the participant as provided in Section 10 

  

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hereof; provided, however, that for the first Offering Period, payroll deductions shall commence on the first pay day on or following the end of the
Enrollment Window. 
 (c) All payroll deductions made for a participant shall be credited to his or her account under the Plan
and shall be withheld in whole percentages only. A participant may not make any additional payments into such account. 
 (d)
A participant may discontinue his or her participation in the Plan as provided in Section 10 hereof, or may increase or decrease the rate of his or her payroll deductions during the Offering Period by completing or filing with the Company a new
subscription agreement authorizing a change in payroll deduction rate. The Administrator may, in its discretion, limit the nature and/or number of participation rate changes during any Offering Period. The change in rate shall be effective with the
first full payroll period following five (5) business days after the Company’s receipt of the new subscription agreement unless the Company elects to process a given change in participation more quickly. 
 (e) Notwithstanding the foregoing, to the extent necessary to comply with Section 423(b)(8) of the Code and Section 3(c) hereof,
a participant’s payroll deductions may be decreased to zero percent (0%) at any time during an Offering Period. Payroll deductions shall recommence at the rate provided in such participant’s subscription agreement at the beginning of the
first Offering Period which is scheduled to end in the following calendar year, unless terminated by the participant as provided in Section 10 hereof. 
 (f) At the time the option is exercised, in whole or in part, or at the time some or all of the Company’s Common Stock issued under the Plan is disposed of, the participant must make adequate provision for the
Company’s or its Subsidiary’s federal, state, or any other tax liability payable to any authority, national insurance, social security or other tax withholding obligations, if any, which arise upon the exercise of the option or the
disposition of the Common Stock. At any time, the Company or its Subsidiary may, but shall not be obligated to, withhold from the participant’s compensation the amount necessary for the Company or its Subsidiary to meet applicable withholding
obligations, including any withholding required to make available to the Company or its Subsidiary any tax deductions or benefits attributable to sale or early disposition of Common Stock by the Eligible Employee. 
 7. Grant of Option. On the Offering Date of each Offering Period, each Eligible Employee participating in such Offering Period shall be granted an
option to purchase on each Exercise Date during such Offering Period (at the applicable Purchase Price) up to a number of shares of the Company’s Common Stock determined by dividing such Eligible Employee’s payroll deductions accumulated
prior to such Exercise Date by the applicable Purchase Price; provided that in no event shall an Eligible Employee be permitted to purchase during each Offering Period more than 1,000 shares of the Company’s Common Stock (subject to any
adjustment pursuant to Section 19), and provided further that such purchase shall be subject to the limitations set forth in Sections 3(c) and 13 hereof. The Eligible Employee may accept the grant of such option by turning in a completed
Subscription Agreement (attached hereto as Exhibit A) to the Company on or prior to an Offering Date, or with respect to the first Offering Period, prior to the last day of the Enrollment Window. The Administrator may, for future Offering
Periods, increase or decrease, in its absolute discretion, the maximum number of shares of the Company’s Common Stock an Eligible Employee may 

  

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purchase during each Offering Period. Exercise of the option shall occur as provided in Section 8 hereof, unless the participant has withdrawn pursuant
to Section 10 hereof. The option shall expire on the last day of the Offering Period. 
 8. Exercise of Option. 
 (a) Unless a participant withdraws from the Plan as provided in Section 10 hereof, his or her option for the purchase of shares shall
be exercised automatically on the Exercise Date, and the maximum number of full shares subject to option shall be purchased for such participant at the applicable Purchase Price with the accumulated payroll deductions in his or her account. No
fractional shares shall be purchased; any payroll deductions accumulated in a participant’s account which are not sufficient to purchase a full share shall be retained in the participant’s account for the subsequent Offering Period,
subject to earlier withdrawal by the participant as provided in Section 10 hereof. Any other funds left over in a participant’s account after the Exercise Date shall be returned to the participant. During a participant’s lifetime, a
participant’s option to purchase shares hereunder is exercisable only by him or her. 
 (b) If the Administrator
determines that, on a given Exercise Date, the number of shares with respect to which options are to be exercised may exceed (i) the number of shares of Common Stock that were available for sale under the Plan on the Offering Date of the
applicable Offering Period, or (ii) the number of shares available for sale under the Plan on such Exercise Date, the Administrator may in its sole discretion provide that the Company shall make a pro rata allocation of the shares of Common
Stock available for purchase on such Exercise Date in as uniform a manner as shall be practicable and as it shall determine in its sole discretion to be equitable among all participants exercising options to purchase Common Stock on such Exercise
Date. The Company may make a pro rata allocation of the shares available on the Offering Date of any applicable Offering Period pursuant to the preceding sentence, notwithstanding any authorization of additional shares for issuance under the Plan by
the Company’s stockholders subsequent to such Offering Date. 
 9. Delivery. As soon as reasonably practicable after each
Exercise Date on which a purchase of shares occurs, the Company shall arrange the delivery to each participant the shares purchased upon exercise of his or her option in a form determined by the Administrator. 
 10. Withdrawal. 
 (a)
A participant may withdraw all but not less than all the payroll deductions credited to his or her account and not yet used to exercise his or her option under the Plan at any time by giving written notice to the Company in the form determined by
the Administrator (which may be similar to the form attached as Exhibit B to this Plan). All of the participant’s payroll deductions credited to his or her account shall be paid to such participant promptly after receipt of notice of
withdrawal and such participant’s option for the Offering Period shall be automatically terminated, and no further payroll deductions for the purchase of shares shall be made for such Offering Period. If a participant withdraws from an Offering
Period, payroll deductions shall not resume at the beginning of the succeeding Offering Period unless the participant delivers to the Company a new subscription agreement. 
  

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 (b) A participant’s withdrawal from an Offering Period shall not have any effect
upon his or her eligibility to participate in any similar plan which may hereafter be adopted by the Company or in succeeding Offering Periods which commence after the termination of the Offering Period from which the participant withdraws.

 11. Termination of Employment. Upon a participant’s ceasing to be an Eligible Employee, for any reason, he or she shall be
deemed to have elected to withdraw from the Plan and the payroll deductions credited to such participant’s account during the Offering Period but not yet used to purchase shares of Common Stock under the Plan shall be returned to such
participant or, in the case of his or her death, to the person or persons entitled thereto under Section 15, and such participant’s option shall be automatically terminated. 
 12. Interest. No interest shall accrue on the payroll deductions of a participant in the Plan. 
 13. Stock. 
 (a)
Subject to adjustment upon changes in capitalization of the Company as provided in Section 19 hereof, the maximum number of shares of the Company’s Common Stock which shall be made available for sale under the Plan shall be 550,000 shares.

 (b) Until the shares are issued (as evidenced by the appropriate entry on the books of the Company or of a duly authorized
transfer agent of the Company), a participant shall only have the rights of an unsecured creditor with respect to such shares, and no right to vote or receive dividends or any other rights as a stockholder shall exist with respect to such shares.

 (c) Shares to be delivered to a participant under the Plan shall be registered in the name of the participant or in the
name of the participant and his or her spouse. 
 14. Administration. The Plan will be administered by an Administrator which shall be
either (A) the Board or (B) a Committee appointed by the Board, which committee will be constituted to satisfy all applicable law. The Administrator shall administer the Plan and shall have full and exclusive discretionary authority to
construe, interpret and apply the terms of the Plan, to determine eligibility and to adjudicate all disputed claims filed under the Plan. Every finding, decision and determination made by the Administrator shall, to the full extent permitted by law,
be final and binding upon all parties. Notwithstanding any provision to the contrary in this Plan, the Administrator may adopt rules or procedures relating to the operation and administration of the Plan to accommodate the specific requirements of
local laws and procedures for jurisdictions outside of the United States. Without limiting the generality of the foregoing, the Administrator is specifically authorized to adopt rules and procedures regarding eligibility to participate, the
definition of Compensation, handling of payroll deductions, making of contributions to the Plan (including, without limitation, in forms other than payroll deductions), establishment of bank or trust accounts to hold payroll deductions, payment of
interest, conversion of local currency, obligations to pay payroll tax, determination of beneficiary designation requirements, withholding procedures and handling of stock certificates which vary with local requirements. 
  

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 15. Designation of Beneficiary. 
 (a) A participant may file a designation of a beneficiary who is to receive any shares and cash, if any, from the participant’s
account under the Plan in the event of such participant’s death subsequent to an Exercise Date on which the option is exercised but prior to delivery to such participant of such shares and cash. In addition, a participant may file a designation
of a beneficiary who is to receive any cash from the participant’s account under the Plan in the event of such participant’s death prior to exercise of the option. If a participant is married and the designated beneficiary is not the
spouse, spousal consent shall be required for such designation to be effective. 
 (b) Such designation of beneficiary may be
changed by the participant at any time by notice in a form determined by the Administrator. In the event of the death of a participant and in the absence of a beneficiary validly designated under the Plan who is living at the time of such
participant’s death, the Company shall deliver such shares and/or cash to the executor or administrator of the estate of the participant, or if no such executor or administrator has been appointed (to the knowledge of the Company), the Company,
in its discretion, may deliver such shares and/or cash to the spouse or to any one or more dependents or relatives of the participant, or if no spouse, dependent or relative is known to the Company, then to such other person as the Company may
designate. 
 (c) All beneficiary designations shall be in such form and manner as the Administrator may designate from time
to time. 
 16. Transferability. Neither payroll deductions credited to a participant’s account nor any rights with regard to the
exercise of an option or to receive shares under the Plan may be assigned, transferred, pledged or otherwise disposed of in any way (other than by will, the laws of descent and distribution or as provided in Section 15 hereof) by the
participant. Any such attempt at assignment, transfer, pledge or other disposition shall be without effect, except that the Company may treat such act as an election to withdraw funds from an Offering Period in accordance with Section 10
hereof. 
 17. Use of Funds. All payroll deductions received or held by the Company under the Plan may be used by the Company for any
corporate purpose, and the Company shall not be obligated to segregate such payroll deductions. Until shares are issued, participants shall only have the rights of an unsecured creditor. 
 18. Reports. Individual accounts shall be maintained for each participant in the Plan. Statements of account shall be given to participating
Eligible Employees at least annually, which statements shall set forth the amounts of payroll deductions, the Purchase Price, the number of shares purchased and the remaining cash balance, if any. 
  

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 19. Adjustments Upon Changes in Capitalization, Dissolution, Liquidation, Merger or Change in
Control. 
 (a) Changes in Capitalization. Subject to any required action by the stockholders of the Company, the
maximum number of shares of the Company’s Common Stock which shall be made available for sale under the Plan, the maximum number of shares each participant may purchase each Offering Period (pursuant to Section 7), as well as the price per
share and the number of shares of Common Stock covered by each option under the Plan which has not yet been exercised shall be proportionately adjusted for any increase or decrease in the number of issued shares of Common Stock resulting from a
stock split, reverse stock split, stock dividend, combination or reclassification of the Common Stock, or any other change in the number of shares of Common Stock effected without receipt of consideration by the Company; provided, however, that
conversion of any convertible securities of the Company shall not be deemed to have been “effected without receipt of consideration.” Such adjustment shall be made by the Administrator, whose determination in that respect shall be final,
binding and conclusive. Except as expressly provided herein, no issuance by the Company of shares of stock of any class, or securities convertible into shares of stock of any class, shall affect, and no adjustment by reason thereof shall be made
with respect to, the number or price of shares of Common Stock subject to an option. 
 (b) Dissolution or Liquidation.
In the event of the proposed dissolution or liquidation of the Company, the Offering Period then in progress shall be shortened by setting a new Exercise Date (the “New Exercise Date”), and shall terminate immediately prior to the
consummation of such proposed dissolution or liquidation, unless provided otherwise by the Administrator. The New Exercise Date shall be before the date of the Company’s proposed dissolution or liquidation. The Administrator shall notify each
participant in writing, at least ten (10) business days prior to the New Exercise Date, that the Exercise Date for the participant’s option has been changed to the New Exercise Date and that the participant’s option shall be exercised
automatically on the New Exercise Date, unless prior to such date the participant has withdrawn from the Offering Period as provided in Section 10 hereof. 
 (c) Merger or Change in Control. In the event of a merger or Change in Control, each outstanding option shall be assumed or an
equivalent option substituted by the successor corporation or a Parent or Subsidiary of the successor corporation. In the event that the successor corporation refuses to assume or substitute for the option, the Offering Period then in progress shall
be shortened by setting a New Exercise Date and shall end on the New Exercise Date. The New Exercise Date shall be before the date of the Company’s proposed merger or Change in Control. The Administrator shall notify each participant in
writing, at least ten (10) business days prior to the New Exercise Date, that the Exercise Date for the participant’s option has been changed to the New Exercise Date and that the participant’s option shall be exercised automatically
on the New Exercise Date, unless prior to such date the participant has withdrawn from the Offering Period as provided in Section 10 hereof. 
 20. Amendment or Termination. 
 (a) The Administrator may at any time and for any reason terminate or amend
the Plan. Except as provided in Section 19 and this Section 20 hereof, no amendment may make any 

  

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change in any option theretofore granted which adversely affects the rights of any participant unless their consent is obtained. To the extent necessary to
comply with Section 423 of the Code (or any successor rule or provision or any other applicable law, regulation or stock exchange rule), the Company shall obtain stockholder approval of any amendment in such a manner and to such a degree as
required. 
 (b) Without stockholder approval and without regard to whether any participant rights may be considered to have
been “adversely affected,” the Administrator shall be entitled to change the Offering Periods, limit the frequency and/or number of changes in the amount withheld during an Offering Period, establish the exchange ratio applicable to
amounts withheld in a currency other than U.S. dollars, permit payroll withholding in excess of the amount designated by a participant in order to adjust for delays or mistakes in the Company’s processing of properly completed withholding
elections, establish reasonable waiting and adjustment periods and/or accounting and crediting procedures to ensure that amounts applied toward the purchase of Common Stock for each participant properly correspond with amounts withheld from the
participant’s Compensation, and establish such other limitations or procedures as the Administrator determines in its sole discretion advisable which are consistent with the Plan. 
 (c) Without regard to whether any participant’s rights may be considered to have been “adversely affected”, in the event
the Administrator determines that the ongoing operation of the Plan may result in unfavorable financial accounting consequences, the Board may, in its discretion and, to the extent necessary or desirable, modify or amend the Plan to reduce or
eliminate such accounting consequence including: 
 (i) increasing the Purchase Price for any Offering Period including an
Offering Period underway at the time of the change in Purchase Price; 
 (ii) shortening any Offering Period so that Offering
Period ends on a new Exercise Date, including an Offering Period underway at the time of the Board action; and 
 (iii)
reducing the number of shares that may be purchased upon exercise of outstanding options. 
 Such modifications or amendments shall not require stockholder
approval or the consent of any Plan participants. 
 21. Notices. All notices or other communications by a participant to the Company
under or in connection with the Plan shall be deemed to have been duly given when received in the form and manner specified by the Company at the location, or by the person, designated by the Company for the receipt thereof. 
 22. Conditions Upon Issuance of Shares. Shares shall not be issued with respect to an option unless the exercise of such option and the issuance
and delivery of such shares pursuant thereto shall comply with all applicable provisions of law, domestic or foreign, including, without limitation, the Securities Act of 1933, as amended, the Exchange Act, the rules and regulations promulgated
thereunder, and the requirements of any stock exchange upon which the shares may then be listed, and shall be further subject to the approval of counsel for the Company with respect to such compliance. 
  

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 As a condition to the exercise of an option, the Company may require the person
exercising such option to represent and warrant at the time of any such exercise that the shares are being purchased only for investment and without any present intention to sell or distribute such shares if, in the opinion of counsel for the
Company, such a representation is required by any of the aforementioned applicable provisions of law. 
 23. Term of Plan. The Plan
shall become effective upon the earlier to occur of its adoption by the Board of Directors or its approval by the stockholders of the Company. It shall continue in effect until the later of (i) the date it is terminated under Section 20
hereof or (ii) the date which is ten (10) years after the date such Plan is approved by the Board. 
 24. Stockholder
Approval. The Plan will be subject to approval by the stockholders of the Company within twelve (12) months after the date the Plan is adopted by the Board. Such stockholder approval will be obtained in the manner and to the degree required
under Applicable Laws. 
  

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 EXHIBIT A 
 SENORX, INC. 
 EMPLOYEE STOCK PURCHASE PLAN 
 SUBSCRIPTION AGREEMENT 
  

			
	            Original Application
	  	Offering Date:                        
	            Change in Payroll Deduction Rate
	  	
	            Change of Beneficiary(ies)
	  	

  

	1.	                                      
   hereby elects to participate in the SenoRx, Inc. Employee Stock Purchase Plan (the “Employee Stock Purchase Plan”) and subscribes to purchase shares of SenoRx, Inc.’s (the “Company”) Common Stock in
accordance with this Subscription Agreement and the Employee Stock Purchase Plan. 

	 	

	2.	I hereby authorize payroll deductions from each paycheck in the amount of         % of my Compensation on each pay day (from 0 to 10%)
during the Offering Period in accordance with the Employee Stock Purchase Plan. (Please note that no fractional percentages are permitted.) 

  

	3.	I understand that said payroll deductions shall be accumulated for the purchase of shares of Common Stock at the applicable Purchase Price determined in accordance with the Employee
Stock Purchase Plan. I understand that if I do not withdraw from an Offering Period, any accumulated payroll deductions will be used to automatically exercise my option and purchase Common Stock under the Employee Stock Purchase Plan.

  

	4.	I have received a copy of the complete Employee Stock Purchase Plan and its accompanying prospectus. I understand that my participation in the Employee Stock Purchase Plan is in all
respects subject to the terms of the Plan. 

  

	5.	Shares purchased for me under the Employee Stock Purchase Plan should be issued in the name(s) of (Eligible Employee or Eligible Employee and Spouse only). 

 

	6.	 I understand that if I dispose of any shares received by me pursuant to the Employee Stock Purchase Plan within 2 years after the Offering Date (the first day of
the Offering Period during which I purchased such shares) or one year after the Exercise Date, I will be treated for federal income tax purposes as having received ordinary income at the time of such disposition in an amount equal to the excess of
the fair market value of the shares at the time such shares were purchased by me over the price which I paid for the shares. I hereby agree to notify the Company in writing within 30 days after the date of any disposition of my shares and I will
make adequate provision for Federal, state or other tax withholding 

	 	 
obligations, if any, which arise upon the disposition of the Common Stock. The Company may, but will not be obligated to, withhold from my
compensation the amount necessary to meet any applicable withholding obligation including any withholding necessary to make available to the Company any tax deductions or benefits attributable to sale or early disposition of Common Stock by me. If I
dispose of such shares at any time after the expiration of the 2-year and 1-year holding periods, I understand that I will be treated for federal income tax purposes as having received income only at the time of such disposition, and that such
income will be taxed as ordinary income only to the extent of an amount equal to the lesser of (1) the excess of the fair market value of the shares at the time of such disposition over the purchase price which I paid for the shares, or
(2) 15% of the fair market value of the shares on the first day of the Offering Period. The remainder of the gain, if any, recognized on such disposition will be taxed as capital gain. 

  

	7.	I hereby agree to be bound by the terms of the Employee Stock Purchase Plan. The effectiveness of this Subscription Agreement is dependent upon my eligibility to participate in the
Employee Stock Purchase Plan. 

  

	8.	In the event of my death, I hereby designate the following as my beneficiary(ies) to receive all payments and shares due me under the Employee Stock Purchase Plan:

  

			
	 NAME: (Please print)
	  	  
		  	(First)                                 (Middle)
                                (Last)

  

					
	  	 		  	  
	 Relationship
	 		  	
	  	 		  	  
	 Percentage Benefit
	 		  	 (Address)

  

			
	 NAME: (please print)
	  	  
		  	(First)                                 (Middle)
                                (Last)

  

					
	  	 		  	  
	 Relationship
	 		  	
	  	 		  	  
	 Percentage of Benefit
	 		  	 (Address)

  

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	 Employee’s Social
 Security Number:
	 		 	   
			
	 Employee’s Address:
	 		 	   
			
	 	 		 	   
			
	 	 		 	   
	 	 		 	 

 I UNDERSTAND THAT THIS SUBSCRIPTION AGREEMENT SHALL REMAIN IN EFFECT THROUGHOUT SUCCESSIVE OFFERING PERIODS UNLESS
TERMINATED BY ME. 
  

									
				
	Dated:	 	  	 		 	  
		 		 		 	Signature of Employee
				
		 		 		 	  
		 		 		 	Spouse’s Signature (If beneficiary other than spouse)

  

 -3- 

 EXHIBIT B 
 SENORX, INC. 
 EMPLOYEE STOCK PURCHASE PLAN 
 NOTICE OF WITHDRAWAL 
 The undersigned
participant in the Offering Period of the SenoRx, Inc. Employee Stock Purchase Plan that began on ____________, ______ (the “Offering Date”) hereby notifies the Company that he or she hereby withdraws from the Offering Period. He or she
hereby directs the Company to pay to the undersigned as promptly as practicable all the payroll deductions credited to his or her account with respect to such Offering Period. The undersigned understands and agrees that his or her option for such
Offering Period will be automatically terminated. The undersigned understands further that no further payroll deductions will be made for the purchase of shares in the current Offering Period and the undersigned shall be eligible to participate in
succeeding Offering Periods only by delivering to the Company a new Subscription Agreement. 
  

	
	Name and Address of Participant:
	
	   
	
	   
	
	   
	

  

			
	Signature:
	
	  
		
	Date:Fourth Amended and Restated Investors' Rights Agreement

 Exhibit 10.5 
 FOURTH AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT 
 This Fourth Amended and Restated
Investors’ Rights Agreement (“Rights Agreement”) is entered into as of May 3, 2006 by and among SenoRx, Inc., a Delaware corporation (the “Company”), and certain holders of the Company’s capital stock
(collectively, the “Investors”). 
 WHEREAS, the Company and certain of the Investors are parties to the Third Amended
Investors’ Rights Agreement dated June 28, 2001, as later amended (the “Prior Agreement”); 
 WHEREAS, the Company and
certain of the Investors are parties to Note Purchase Agreement dated as of even date herewith (the “Purchase Agreement”) by and among the Company and those Investors; 
 WHEREAS, the obligations of the Company and those Investors who are parties to the Purchase Agreement are conditioned upon, among other things, the
execution and delivery of this Agreement by the Company and the Investors; and 
 WHEREAS, the Company and the Investors desire to amend,
restate, and replace in its entirety the Prior Agreement with this Agreement. 
 1. Certain Definitions. As used in this Agreement,
the following terms shall have the following respective meanings: 
 (a) “Commission” shall mean the
Securities and Exchange Commission or any other federal agency at the time administering the Securities Act. 
 (b)
“Holder” shall mean the Investors or other persons holding Registrable Securities or securities convertible into Registrable Securities and any person holding such securities to whom the rights under this Agreement have been
transferred in accordance with Section 4(i) hereof. 
 (c) “Initiating Holders” shall mean any Holder or
Holders who in the aggregate hold at least 30% of the Registrable Securities. 
 (d) “Major Stockholder”
shall mean any holder of Common Stock or Preferred Stock, along with such holders permitted transferees or assignees, who own in the aggregate, beneficially or otherwise, at least 500,000 shares of Common Stock or Preferred Stock (or any combination
thereof). 
 (e) “Preferred Stock” or “Shares” shall mean all outstanding shares of Series A
Preferred Stock, Series B Preferred Stock, and Series C Preferred Stock. 
 (f) “Registrable Securities”
means (i) the Common Stock issued or issuable upon conversion of the Preferred Stock (the “Conversion Stock”) and (ii) any Common Stock of the Company issued or issuable with respect to, or in exchange for or in replacement of
the Conversion Stock or other securities convertible into or exercisable for Preferred Stock upon any stock split, stock dividend, recapitalization, or similar event, provided, however, that shares of Common Stock or other securities shall only be
treated as Registrable Securities for the purposes of this Agreement 

 
(A) if and so long as they have not been sold to or through a broker or dealer or underwriter in a public distribution or a public securities transaction, or
(B) prior to the date such securities have been sold or are all available for immediate sale in the opinion of counsel to the Company in a transaction exempt from the prospectus delivery requirements of the Securities Act so that all transfer
restrictions and legends with respect thereto are removed upon the consummation of such sale. 
 (g) The terms
“register,” “registered” and “registration” refer to a registration effected by preparing and filing a registration statement in compliance with the Securities Act, and the declaration or ordering
of the effectiveness of such registration statement. 
 (h) “Registration Expenses” shall mean all expenses,
except as otherwise stated below, incurred by the Company in complying with Sections 4(a), 4(b) and 4(c) hereof, including, without limitation, all registration, qualification and filing fees, printing expenses, escrow fees, fees and disbursements
of counsel for the Company, fees and disbursement of one counsel to the Holders, blue sky fees and expenses, the expense of any special audits incident to or required by any such registration (but excluding the compensation of regular employees of
the Company which shall be paid in any event by the Company). 
 (i) “Restricted Securities” shall mean the
securities of the Company required to bear the legend set forth in Section 2(b) hereof. 
 (j) “Securities
Act” shall mean the Securities Act of 1933, as amended, or any similar federal statute and the rules and regulations of the Commission thereunder, all as the same shall be in effect at the time. 
 (k) “Selling Expenses” shall mean all underwriting discounts, selling commissions and stock transfer taxes, if any,
applicable to the securities registered by the Holders. 
 2. Transferability. 
 (a) Restrictions on Transferability. The Shares and the Registrable Securities shall not be sold, assigned, transferred or pledged
except upon the conditions specified in this Section 2, which conditions are intended to ensure compliance with the provisions of the Securities Act. The Investors and the Holders will cause any proposed purchaser, assignee, transferee, or
pledgee of the Shares or the Registrable Securities held by such Investor or Holders to agree to take and hold such securities subject to the provisions and upon the conditions specified in this Section 2. 
 (b) Restrictive Legend. Each certificate representing (i) the Shares, (ii) the Registrable Securities and (iii) any
other securities issued in respect of the Shares or the Registrable Securities upon any merger, consolidation or similar event, shall (unless otherwise permitted by the provisions of Section 2(c) below) be stamped or otherwise imprinted with a
legend in the following form (in addition to any legend required under applicable state securities laws): 
 THE SHARES REPRESENTED BY THIS
CERTIFICATE HAVE BEEN ACQUIRED FOR INVESTMENT AND HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. SUCH SHARES MAY NOT BE SOLD OR TRANSFERRED IN THE ABSENCE OF SUCH 

  

 2 

 
REGISTRATION UNLESS THE TRANSFER IS IN ACCORDANCE WITH RULE 144 OR SIMILAR RULE OR UNLESS THE COMPANY RECEIVES AN OPINION OF COUNSEL REASONABLY ACCEPTABLE TO
IT STATING THAT SUCH SALE OR TRANSFER IS EXEMPT FROM THE REGISTRATION AND PROSPECTUS DELIVERY REQUIREMENTS OF SUCH ACT. 
 The Investors and
Holders consent to the Company making a notation on its records and giving instructions to any transfer agent of the Shares or the Registrable Securities in order to implement the restrictions on transfer established in this Section 2.

 (c) Notice of Proposed Transfers. The holder of each certificate representing Restricted Securities by acceptance
thereof agrees to comply in all respects with the provisions of this Section 2(c). Prior to any proposed sale, assignment, transfer or pledge of any Restricted Securities (other than (i) a transfer not involving a change in beneficial
ownership, or (ii) in transactions involving the distribution without consideration of Restricted Securities by any Holder or Investor to any of its partners, members or retired partners or members, or to the estate of any of its partners,
members or retired partners or members, (iii) a transfer to an affiliated fund, partnership or company, which is not a competitor of the Company, subject to compliance with applicable securities laws, or (iv) transfers in compliance with
Rule 144, so long as the Company is furnished with satisfactory evidence of compliance with such Rule), unless there is in effect a registration statement under the Securities Act covering the proposed transfer, the holder thereof shall give written
notice to the Company of such holder’s intention to effect such transfer, sale, assignment or pledge. Each such notice shall describe the manner and circumstances of the proposed transfer, sale, assignment or pledge in sufficient detail, and
shall be accompanied, at such holder’s expense by either (i) a written opinion addressed to the Company of legal counsel who shall, and whose legal opinion shall, be reasonably satisfactory to the Company addressed to the Company, to the
effect that the proposed transfer of the Restricted Securities may be effected without registration under the Securities Act, or (ii) a “no action” letter from the Commission to the effect that the transfer of such securities without
registration will not result in a recommendation by the staff of the Commission that action be taken with respect thereto, whereupon the holder of such Restricted Securities shall be entitled to transfer such Restricted Securities in accordance with
the terms of the notice delivered by the holder to the Company. Each certificate evidencing the Restricted Securities transferred as above provided shall bear, except if such transfer is made pursuant to Rule 144, the appropriate restrictive legend
set forth in Section 2(b) above, except that such certificate shall not bear such restrictive legend if in the opinion of counsel for such holder and in the reasonable opinion of the Company such legend is not required in order to establish
compliance with any provision of the Securities Act. 
 (d) Removal of Restrictions on Transfer of Securities. Any
legend referred to in Section 2(b) hereof stamped on a certificate evidencing (i) the Shares, (ii) the Registrable Securities or (iii) any other securities issued in respect of the Shares or the Registrable Securities upon any
merger, consolidation or similar event and the stock transfer instructions and record notations with respect to such security shall be removed and the Company shall issue a certificate without such legend to the holder of such security if such
security is registered under the Securities Act, or if such holder provides the Company with an opinion of counsel (which may be counsel for the Company) reasonably acceptable to the Company to the effect that a public sale or transfer of such
security may 

  

 3 

 
be made without registration under the Securities Act or (iii) such holder provides the Company with reasonable assurances, which may, at the option of
the Company, include an opinion of counsel satisfactory to the Company, that such security can be sold pursuant to Section (k) of Rule 144 under the Securities Act. 
 3. Information Rights. 
 (a) Delivery of Financial Statements. The Company
shall deliver to each Major Stockholder: 
 (i) as soon as practicable, but in any event within ninety (90) days after
the end of each fiscal year of the Company commencing with the fiscal year ending December 31, 1999 a balance sheet, and statements of operations and cash flow for such fiscal year. Such year-end financial reports shall be in reasonable detail,
prepared in accordance with generally accepted accounting principles (“GAAP”), and audited and certified by independent public accountants of nationally recognized standing selected by the Company; 
 (ii) within thirty (30) days of the end of each month, an unaudited statement of operations and consolidated balance sheet for and as
of the end of such month, in reasonable detail (including comparisons to the operating budget) and prepared in accordance with GAAP, subject to year end audit adjustments and the absence of footnotes; and 
 (iii) such other information relating to the financial condition, business, prospects or corporate affairs as such person may from time to
time reasonably request, provided, however, that the Company shall not be obligated to provide information which it deems in good faith to be proprietary (unless such Investor agrees to enter into a confidentiality agreement with the Company),
immaterial, unreasonable, or unduly burdensome to provide. 
 (b) Provision of Information to Board of Directors. The
Company shall deliver to each member of the Company’s Board of Directors: 
 (i) within thirty (30) days prior to
the end of each fiscal year, an operating budget forecasting the Company’s revenues, expenses, and cash position on a month-to-month basis for the next fiscal year and any other budgets or revised budgets prepared by the Company; and

 (ii) notification of material litigation; 
 (iii) copies of all filings made with the Securities and Exchange Commission, if any. 
 (c) Assignment of Rights to Financial Information. Subject to the limitations set forth in Section 3(a) the rights granted
pursuant to Section 3(a) may be assigned or otherwise conveyed by the Holder or Holders or by any subsequent transferee to: (i) an investor who acquires at least 500,000 Shares or an equivalent amount of Registrable Securities (or a
combination thereof), other than a competitor of the Company, as reasonably determined by the Board of Directors of the Company excluding any director with an interest in such transferee; (ii) a partner or member of a Holder who, together with
such Holder, holds at least 500,000 Shares or an equivalent amount of 

  

 4 

 
Registrable Securities (or a combination thereof); or (iii) an affiliate of a Holder/transferor who, together with such Holder, holds 500,000 Shares or
an equivalent amount of Registrable Securities (or a combination thereof) and such affiliate is primarily engaged in the business of venture capital investment; provided, however, that the information rights set forth in Section 3(a) may be
transferred to no more than five (5) affiliates by such Holder/transferor. In the event of a transfer of rights each such transferor shall provide written notice of such assignment or conveyance to the Company. 
 (d) Confidential Information. Each recipient of such information relating to the financial condition, business, prospects or
corporate affairs of the corporation acknowledges that all such information is confidential information and that the release or disclosure of such information would materially and adversely effect the corporation. As such, each recipient represents
and warrants that he, she or it, and/or any affiliate of such recipient, shall hold in trust and maintain the confidential nature of all such information. 
 (e) Termination of Information Rights. The obligation of the Company to provide the information set forth above in Section 3(a) shall terminate upon the earlier of (i) the closing of a firm commitment
underwritten public offering pursuant to an effective registration statement on Form S-1 under the Act, covering the offer and sale of the Company’s Common Stock to the general public resulting in gross proceeds to the Company of at least
$20,000,000 (as appropriately adjusted for stock splits, stock dividends, combinations, reclassifications and similar events) (a “Qualified Public Offering”); or (ii) a merger, consolidation or sale of all or substantially all of the
assets of the Company to another corporation, person, or entity which will result in the Company’s stockholders immediately prior to such transaction not holding (by virtue of such shares or securities issued solely with respect thereto) at
least fifty percent (50%) of the voting power of the surviving, continuing or purchasing entity. 
 4. Registration Rights.

 (a) Requested Registration. 
 (i) Requested Registration. If the Company shall receive from Initiating Holders a written request that the Company file a
registration statement for the shares of such Initiating Holders in which the anticipated aggregate proceeds of which net of underwriting discounts and commissions would equal or exceed: (i) $20,000,000 if no registered public offering has
occurred or (ii) $5,000,000 if a registered public offering has occurred, the Company will: 
 (1) within ten days of
the receipt by the Company of such notice, give written notice of the proposed registration, qualification or compliance to all other Holders; and 
 (2) as soon as practicable and in any event within sixty (60) days, use its best efforts to effect such registration, qualification or compliance (including, without limitation, appropriate qualification under
applicable blue sky or other state securities laws and appropriate compliance with applicable regulations issued under the Securities Act and any other governmental requirements or regulations) as may be so requested and as would permit or
facilitate the sale and distribution of all or such portion of such Registrable Securities as are specified in such request, 

  

 5 

 
together with all or such portion of the Registrable Securities of any Holder or Holders joining in such request as are specified in a written request
received by the Company within 20 days after receipt of such written notice from the Company; 
 Provided, however, that the Company shall
not be obligated to take any action to effect any such registration, qualification or compliance pursuant to this Section 4(a): 
 a) Prior to the earlier of (i) date six (6) months following the effective date of the Company’s first registered public offering of its stock, pursuant to a firm commitment underwritten offering or
(ii) December 31, 2002; 
 b) In any particular jurisdiction in which the Company would be required to execute a
general consent to service of process in effecting such registration, qualification or compliance unless the Company is already subject to service in such jurisdiction and except as may be required by the Securities Act; 
 c) During the period starting with the date sixty (60) days prior to the Company’s estimated date of filing of, and ending on
the date three (3) months immediately following the effective date of, any registration statement pertaining to securities of the Company (other than a registration of securities in a Rule 145 transaction or with respect to an employee benefit
plan, in which case there shall be no such limitation on the Company’s obligation, or with respect to the Company’s first registered public offering of its stock in which case the period shall end on the date six (6) months following
the effective date), provided that the Company is actively employing in good faith all reasonable efforts to cause such registration statement to become effective; 
 d) After the Company has effected two (2) such registrations pursuant to this Section 4(a)(i) and such registrations have been
declared or ordered effective and the securities offered thereunder have been sold; and 
 e) If the Company shall furnish to
such Holders a certificate signed by the President of the Company stating that in the good faith judgment of the Board of Directors it would be seriously detrimental to the Company or its stockholders for a registration statement to be filed in the
near future, then the Company’s obligation to use its best efforts to register, qualify or comply under this Section 4(a) shall be deferred for a period not to exceed 90 days from the date of receipt of written request from the Initiating
Holders; provided, however, that the Company shall not exercise such right more than once in any twelve-month period. 
 Subject to the
foregoing clauses (a) through (e), the Company shall file a registration statement covering the Registrable Securities so requested to be registered as soon as practicable and in any event within sixty (60) days after receipt of the
request or requests of the Initiating Holders. 
 (ii) Underwriting. In the event that a registration pursuant to
Section 4(a) is for a registered public offering involving an underwriting the Company shall so advise the Holders as part of the notice given pursuant to Section 4(a)(i)(1). In such event, the right of any Holder to registration pursuant
to Section 4(a) shall be conditioned upon such Holder’s participation in the 

  

 6 

 
underwriting arrangements required by this Section 4(a), and the inclusion of such Holder’s Registrable Securities in the underwriting to the
extent requested shall be limited to the extent provided herein. 
 The Company shall (together with all Holders proposing to
distribute their securities through such underwriting) enter into an underwriting agreement in customary form with the managing underwriter of recognized national standing selected for such underwriting by the Company and reasonably acceptable to a
majority of the Holders proposing to distribute their securities through such underwriting. Notwithstanding any other provision of this Section 4(a), if the managing underwriter advises the Initiating Holders in writing that marketing factors
require a limitation of the number of shares to be underwritten, then the Company shall so advise all holders of Registrable Securities and the number of shares of Registrable Securities that may be included in the registration and underwriting
shall be allocated among all Holders thereof in proportion, as nearly as practicable, to the respective amounts of Registrable Securities held by such Holders at the time of filing the registration statement or in such other manner as shall be
agreed to by the Company and Holders of a majority of the Registrable Securities proposed to be included in such registration; provided, however, that the number of Registrable Securities to be included in such underwriting shall not be reduced
unless all other securities are first entirely excluded from such underwriting. No Registrable Securities excluded from the underwriting by reason of the underwriter’s marketing limitation shall be included in such registration. To facilitate
the allocation of shares in accordance with the above provisions, the Company or the underwriters may round the number of shares allocated to any Holder to the nearest 100 shares. 
 If any Holder of Registrable Securities disapproves of the terms of the underwriting, such Holder may elect to withdraw therefrom by
written notice to the Company, the managing underwriter and the Initiating Holders. The Registrable Securities and/or other securities so withdrawn shall also be withdrawn from registration, and such Registrable Securities shall not be transferred
in a public distribution prior to 180 days after the effective date of such registration, or such other shorter period of time as the underwriters may require. 
 (b) Company Registration. 
 (i) Notice of Registration. If at any time or from time to time the Company shall determine to register any of its securities, either for its own account or the account of a security holder or holders, other
than (i) a registration relating solely to employee benefit plans, (ii) a registration relating solely to a Commission Rule 145 transaction, (iii) a registration relating to a Qualified Public Offering or (iv) a registration
pursuant to Section 4(a) hereof, the Company will: 
 (1) promptly give to each Holder written notice thereof; and

 (2) include in such registration (and any related qualification under blue sky laws or other compliance), and in any
underwriting involved therein, all the Registrable Securities specified in a written request or requests, made within 10 days after receipt of such written notice from the Company, by any Holder. 
  

 7 

 (ii) Underwriting. If the registration of which the Company gives notice is for a
registered public offering involving an underwriting, the Company shall so advise the Holders as a part of the written notice given pursuant to Section 4(b)(i)(1). In such event the right of any Holder to registration pursuant to
Section 4(b) shall be conditioned upon such Holder’s participation in such underwriting and the inclusion of Registrable Securities in the underwriting to the extent provided herein. All Holders proposing to distribute their securities
through such underwriting shall (together with the Company) enter into an underwriting agreement in customary form with the managing underwriter selected for such underwriting by the Company. Notwithstanding any other provision of this
Section 4(b), if the managing underwriter determines that marketing factors require a limitation of the number of shares to be underwritten, the managing underwriter may limit the Registrable Securities and other securities to be distributed
through such underwriting; provided, however, that no such reduction shall reduce the number of shares of Registrable Securities included in the registration below twenty-five percent (25%) of the total amount of securities included in such
registration, unless such offering is the first registered public offering of the Company’s stock and such registration does not include shares of any other selling stockholders, in which event any or all of the Registrable Securities may be
excluded if the underwriters make the determination described above. The Company shall so advise all Holders distributing their securities through such underwriting of such limitation and the number of shares of Registrable Securities that may be
included in the registration and underwriting shall be allocated among all Holders in proportion, as nearly as practicable, to the respective amounts of Registrable Securities held by such Holders at the time of filing the registration statement. To
facilitate the allocation of shares in accordance with the above provisions, the Company may round the number of shares allocated to any Holder to the nearest 100 shares. 
 If any Holder disapproves of the terms of any such underwriting, such Holder may elect to withdraw therefrom by written notice to the Company and the managing underwriter. Any Registrable Securities and/or securities
excluded or withdrawn from such underwriting shall be withdrawn from such registration, and shall not be transferred in a public distribution prior to 180 days after the effective date of the registration statement relating thereto, or such other
shorter period of time as the underwriters may require. 
 (iii) Right To Terminate Registration. The Company shall
have the right to terminate or withdraw any registration initiated by it under this Section 4(b) prior to the effectiveness of such registration whether or not any Holder has elected to include securities in such registration. The Registration
Expenses of such withdrawn registration shall be borne by the Company in accordance with Section 4(d) hereof. 
 (c)
Registration on Form S-3. 
 (i) If Holders of at least one percent (1%) of Registrable Securities request that
the Company file a registration statement on Form S-3 (or any successor form to Form S-3), or any similar short form registration statement, for a public offering of Registrable Securities, the reasonably anticipated aggregate price to the public of
which net of underwriting discounts and commissions, would exceed $1,000,000 and the Company is a registrant entitled to use Form S-3 to register the Registrable Securities for such an offering, the Company shall use its best efforts to cause such
Registrable Securities to be registered on such form for the offering and to cause such 

  

 8 

 
Registrable Securities to be qualified in such jurisdictions as the Holder or Holders may reasonably request; provided, however, that the Company shall not
be required to effect more than five (5) registrations (which have been declared effective and pursuant to which all securities registered thereunder have been sold) pursuant to this Section 4(c) or more than one such registration in any
six (6) month period. After the Company’s first public offering of its securities, the Company will use its best efforts to qualify for Form S-3 registration or a similar short-form registration. The provisions of Section 4(a)(ii)
shall be applicable to each registration initiated under this Section 4(c). 
 (ii) Notwithstanding the foregoing, the
Company shall not be obligated to take any action pursuant to this Section 4(c): (i) in any particular jurisdiction in which the Company would be required to execute a general consent to service of process in effecting such registration,
qualification or compliance unless the Company is already subject to service in such jurisdiction and except as may be required by the Securities Act; (ii) if the Company, within ten (10) days of the receipt of the request of the
initiating Holders, gives notice of its bona fide intention to effect the filing of a registration statement with the Commission within ninety (90) days of receipt of such request (other than with respect to a registration statement relating to
a Rule 145 transaction, or an offering solely to employees); (iii) during the period starting with the date ninety (90) days prior to the Company’s estimated date of filing of, and ending on the date six (6) months immediately
following, the effective date of any registration statement pertaining to securities of the Company (other than a registration of securities in a Rule 145 transaction or with respect to an employee benefit plan), provided that the Company is
actively employing in good faith all reasonable efforts to cause such registration statement to become effective; or (iv) if the Company shall furnish to such Holder a certificate signed by the President of the Company stating that in the good
faith judgment of the Board of Directors it would be seriously detrimental to the Company or its stockholders for registration statements to be filed in the near future, then the Company’s obligation to use its best efforts to file a
registration statement shall be deferred for a period not to exceed 90 days from the receipt of the request to file such registration by such Holder; provided, however, that the Company shall not exercise such right more than once in any
twelve-month period. 
 (d) Expenses of Registration. All Registration Expenses incurred in connection with
registrations pursuant to Sections 4(a), 4(b) and the first five (5) such registrations pursuant to Section 4(c) shall be borne by the Company. All Selling Expenses relating to securities registered on behalf of the Holders shall be borne
by the holders of securities included in such registration pro rata with the Company and among each other on the basis of the number of shares so registered. Notwithstanding the foregoing sentence, if a registration proceeding begun pursuant to
Section 4(a) or 4(c) is subsequently withdrawn by the Holders, either (a) if Holders of all of the Registrable Securities to have been registered agree, then the Holders of the Registrable Securities to have been registered shall bear all
such Registration Expenses pro rata on the basis of the number of shares to have been registered, or (b) if all such Holders do not agree, then the Holders will forfeit their right to one registration pursuant to such section, and the Company
shall bear such Registration Expenses. Notwithstanding the foregoing, however, if at the time of the withdrawal, the Holders have learned of a material adverse change in the condition, business or prospects of the Company from that known to the
Holders at the time of their request, of which the Company had knowledge at the time of the request, then the Holders shall not be required to pay any of said Registration Expenses or to forfeit the right to one demand registration and the Company
shall pay the same. 
  

 9 

 (e) Registration Procedures. In the case of each registration, qualification or
compliance effected by the Company pursuant to this Section 4, the Company will keep each Holder advised in writing as to the initiation of each registration, qualification and compliance and as to the completion thereof. At its expense the
Company will: 
 (i) Prepare and file with the Commission a registration statement with respect to such securities and use its
best efforts to cause such registration statement to become and remain effective for at least one hundred eighty (180) days or until the distribution described in the registration statement has been completed; 
 (ii) Prepare and file with the Commission such amendments and supplements to such registration statement and the prospectus used in
connection with such registration statement as may be necessary to comply with the provisions of the Securities Act with respect to the disposition of all securities covered by such registration statement; 
 (iii) Furnish to the Holders participating in such registration and to the underwriters of the securities being registered such reasonable
number of copies of the registration statement, preliminary prospectus, final prospectus and such other documents as such underwriters may reasonably request in order to facilitate the public offering of such securities; 
 (iv) Furnish, at the request of any Holder requesting registration of Registrable Securities on the date such Registrable Securities are
delivered to the underwriters for sale in connection with a registration pursuant to this Section 4(e), (i) an opinion, dated such date, of the counsel representing the Company for the purposes of such registration, in form and substance
as is customarily given to underwriters in an underwritten public offering, addressed to the underwriters, if any, and to the Holders requesting registration of Registrable Securities and (ii) a letter dated such date, from the independent
accountants of the Company, in form and substance as is customarily given by independent accountants to underwriters in an underwritten public offering, addressed to the underwriters, if any, and to the Holders requesting registration of Registrable
Securities; 
 (v) Use its best efforts to register and qualify the securities covered by such registration statement under
such other securities or Blue Sky laws of such jurisdiction as shall be reasonably requested by the Holders, provided that the Company shall not be required in connection therein or as a condition thereto to qualify to do business or to file a
general consent to service of process in any such states or jurisdictions; 
 (vi) In the event of any underwritten public
offering, enter into and perform its obligations under an underwriting agreement, in usual and customary form, with the managing underwriter of such offering; 
 (vii) Notify each Holder of Registrable Securities covered by such registration statement at any time when a prospectus relating thereto
is required to be delivered under the Securities Act of the happening of any event as a result of which the prospectus included in such registration statement, as then in effect, includes an untrue statement of a material fact or omits to state a
material fact required to be stated therein or necessary to make the statements therein 

  

 10 

 
not misleading in the light of the circumstances then existing, such obligation to continue for one hundred eighty (180) days; 
 (viii) Cause all such Registrable Securities registered pursuant hereunder to be listed on each securities exchange on which similar
securities issued by the Company are then listed; and 
 (ix) Provide a transfer agent and registrar for all Registrable
Securities registered pursuant hereunder and a CUSIP number for all such Registrable Securities, in each case not later than the effective date of such registration. 
 (f) Indemnification. 
 (i) The Company will indemnify each Holder, each of its officers, directors, partners and legal counsel, and each person controlling such Holder within the meaning of Section 15 of the Securities Act, with
respect to which registration, qualification or compliance has been effected pursuant to this Section 4, and each underwriter, if any, and each person who controls any underwriter within the meaning of Section 15 of the Securities Act,
against all expenses, claims, losses, damages or liabilities (or actions in respect thereof), including any of the foregoing incurred in settlement of any litigation, commenced or threatened, arising out of or based on any untrue statement (or
alleged untrue statement) of a material fact contained in any registration statement, prospectus, offering circular or other document, or any amendment or supplement thereto, incident to any such registration, qualification or compliance, or based
on any omission (or alleged omission) to state therein a material fact required to be stated therein or necessary to make the statements therein, in light of the circumstances in which they were made, not misleading, or any violation by the Company
of the Securities Act or any rule or regulation promulgated under the Securities Act applicable to the Company in connection with any such registration, qualification or compliance, and the Company will reimburse each such Holder, each of its
officers, directors, partners, and legal counsel and each person controlling such Holder, each such underwriter and each person who controls any such underwriter, for any legal and any other expenses reasonably incurred in connection with
investigating, preparing or defending any such claim, loss, damage, liability or action, provided that the Company will not be liable in any such case to the extent that any such claim, loss, damage, liability or expense arises out of or is based on
any untrue statement or omission or alleged untrue statement or omission, made in reliance upon and in conformity with written information furnished to the Company by an instrument duly executed by such Holder, controlling person or underwriter and
stated to be specifically for use therein. 
 (ii) Each Holder will, if Registrable Securities held by such Holder are
included in the securities as to which such registration, qualification or compliance is being effected, indemnify the Company, each of its directors, officers, and legal counsel, each underwriter, if any, of the Company’s securities covered by
such a registration statement, each person who controls the Company or such underwriter within the meaning of Section 15 of the Securities Act, and each other Holder, each of its officers, directors, partners and legal counsel and each person
controlling such Holder within the meaning of Section 15 of the Securities Act, against all claims, losses, damages and liabilities (or actions in respect thereof) arising out of or based on any untrue statement (or alleged untrue statement) of
a material fact contained in any such registration statement, prospectus, 

  

 11 

 
offering circular or other document, or any omission (or alleged omission) to state therein a material fact required to be stated therein or necessary to
make the statements therein not misleading, and will reimburse the Company, such Holders, such directors, officers, persons, underwriters or control persons for any legal or any other expenses reasonably incurred in connection with investigating or
defending any such claim, loss, damage, liability or action, in each case to the extent, but only to the extent, that such untrue statement (or alleged untrue statement) or omission (or alleged omission) is made in such registration statement,
prospectus, offering circular or other document in reliance upon and in conformity with written information furnished to the Company by an instrument duly executed by such Holder and stated to be specifically for use therein. Notwithstanding the
foregoing, the liability of each Holder under this subsection (b) shall be limited in an amount equal to the net proceeds to each such Holder of Registrable Securities sold as contemplated herein, unless such liability resulted from willful
misconduct by such Holder. A Holder will not be required to enter into any agreement or undertaking in connection with any registration under this Section 4 providing for any indemnification or contribution on the part of such Holder greater
than the Holder’s obligations under this Section 4(f)(ii). 
 (iii) Each party entitled to indemnification under
this Section 4(f) (the “Indemnified Party”) shall give notice to the party required to provide indemnification (the “Indemnifying Party”) promptly after such Indemnified Party has actual knowledge of any claim as to which
indemnity may be sought, and shall permit the Indemnifying Party to assume the defense of any such claim or any litigation resulting therefrom, provided that counsel for the Indemnifying Party, who shall conduct the defense of such claim or
litigation, shall be approved by the Indemnified Party (whose approval shall not unreasonably be withheld), and the Indemnified Party may participate in such defense at such party’s expense, and provided further that the failure of any
Indemnified Party to give notice as provided herein shall not relieve the Indemnifying Party of its obligations under this Section 4 unless the failure to give such notice is materially prejudicial to an Indemnifying Party’s ability to
defend such action and provided further, that the Indemnifying Party shall not assume the defense for matters as to which there is a conflict of interest or separate and different defenses but shall bear the expense of such defense nevertheless. No
Indemnifying Party, in the defense of any such claim or litigation, shall, except with the consent of each Indemnified Party, consent to entry of any judgment or enter into any settlement which does not include as an unconditional term thereof the
giving by the claimant or plaintiff to such Indemnified Party of a release from all liability in respect to such claim or litigation. 
 (iv) If the indemnification provided for in this Section 4(f) is held by a court of competent jurisdiction to be unavailable to an Indemnified Party with respect to any loss, liability, claim, damage, or expense
referred to therein, then the Indemnifying Party, in lieu of indemnifying such Indemnified Party hereunder, shall contribute to the amount paid or payable by such Indemnified Party as a result of such loss, liability, claim, damage, or expense in
such proportion as is appropriate to reflect the relative fault of the Indemnifying Party on the one hand and of the Indemnified Party on the other in connection with the statements or omissions that resulted in such loss, liability, claim, damage,
or expense as well as any other relevant equitable considerations; provided, however, that in no event shall any contribution by a Holder exceed the net proceeds to such Holder of Registrable Securities as contemplated herein, unless such liability
resulted from willful misconduct by such Holder. The relative fault of the Indemnifying Party and of the Indemnified Party shall be determined by reference to, among other things, whether the untrue 

  

 12 

 
or alleged untrue statement of a material fact or the omission to state a material fact relates to information supplied by the Indemnifying Party or by the
Indemnified Party and the parties’ relative intent, knowledge and access to information. 
 (v) The obligations of the
Company and Holders under this Section 4(f) shall survive the completion of any offering of Registrable Securities in a registration statement under this Section 4, and otherwise. 
 (g) Information by Holder. The Holder or Holders of Registrable Securities included in any registration shall furnish to the
Company such information regarding such Holder or Holders, the Registrable Securities held by them and the distribution proposed by such Holder or Holders as the Company may request in writing and as shall be required in connection with any
registration, qualification or compliance referred to in this Section 4. 
 (h) Rule 144 Reporting. With a view to
making available the benefits of certain rules and regulations of the Commission which may at any time permit the sale of the Restricted Securities to the public without registration, after such time as a public market exists for the Common Stock of
the Company, the Company agrees to use its best efforts to: 
 (i) Make and keep public information available, as those terms
are understood and defined in Rule 144 under the Securities Act, at all times after the effective date that the Company becomes subject to the reporting requirements of the Securities Act or the Securities Exchange Act of 1934, as amended;

 (ii) File with the Commission in a timely manner all reports and other documents required of the Company under the
Securities Act and the Securities Exchange Act of 1934, as amended (at any time after it has become subject to such reporting requirements); 
 (iii) Furnish to the Investor, so long as such Investor owns any Restricted Securities, forthwith upon request a written statement by the Company as to its compliance with the reporting requirements of said Rule 144
(at any time after 90 days after the effective date of the first registration statement filed by the Company for an offering of its securities to the general public), and of the Securities Act and the Securities Exchange Act of 1934 (at any time
after it has become subject to such reporting requirements), a copy of the most recent annual or quarterly report of the Company, and such other reports and documents of the Company and other information in the possession of or reasonably obtainable
by the Company as a Purchaser may reasonably request in availing itself of any rule or regulation of the Commission allowing a Purchaser to sell any such securities without registration; and 
 (iv) Take such actions as are necessary to enable the Holders to utilize Form S-3 pursuant to Section 4(c) for the sale of
Registrable Securities; and 
 (i) Transfer of Registration Rights. The rights to cause the Company to register
securities granted Holders under Sections 4(a), 4(b) and 4(c) may be assigned by a Holder to (i) a transferee or assignee who acquires at least (or after such transfer will hold an aggregate of) 500,000 shares of Registrable Securities,
(ii) to another Holder of Registrable Securities who already 

  

 13 

 
possesses registration rights, (iii) to a transferee or assignee acquiring ten percent (10%) or more of the outstanding stock of the Company, or
(iv) to an affiliated limited partnership, a limited partner, a member or general partner or other affiliates of an Investor; provided, however, the Company is, within a reasonable time after such transfer, furnished with written notice of the
name and address of such transferee or assignee and the securities with respect to which such registration rights are being assigned; and provided, further, that such assignment shall be effective only if immediately following such transfer the
further disposition of such securities by the transferee or assignee is restricted under the Securities Act. Notwithstanding the above, such rights may be assigned by a Holder to a limited partner, general partner, member or other affiliate of an
Investor (the “Transferee”) regardless of the number of shares acquired by such Transferee. 
 (j) Standoff
Agreement. Each Holder agrees, in connection with the Company’s initial public offering of the Company’s securities, upon request of the Company or the underwriters managing any underwritten offering of the Company’s securities,
(i) not to sell, make any short sale of, loan, grant any option for the purchase of, or otherwise dispose of any Registrable Securities (other than those included in the registration) without the prior written consent of the Company or such
underwriters, as the case may be, for such period of time (not to exceed one hundred eighty (180) days) from the effective date of such registration as may be requested by the underwriters; provided, that the officers, directors and one percent
(1%) security holders of the Company who own stock of the Company also agree to such restrictions and (ii) to execute any agreement reflecting (i) above as may be requested by the underwriters at the time of the initial public
offering. 
 (k) Termination of Registration Rights. No stockholder shall be entitled to exercise any right provided
for in this Section 4 after five (5) years following the consummation of the sale of Common Stock pursuant to a registration statement filed by the Company under the Securities Act in connection with the initial firm commitment
underwritten offering of its securities to the general public which results in the conversion of the Preferred Stock into Common Stock in accordance with the Company’s Amended and Restated Certificate of Incorporation as in effect at the time
of the offering. 
 5. Investors’ Right of First Offer 
 (a) Right of First Offer Upon Issuances of Securities by the Company. 
 (i) The Company hereby grants, on the terms set forth in this Section 5(a), to each Investor who holds at least 500,000 Shares or
equivalent shares of Registrable Securities (or any combination thereof) the right of first offer to purchase all or any part of such Investor’s pro rata share of the New Securities (as defined in Section 5(a)(ii) which the Company may,
from time to time, propose to sell and issue. The Investors may purchase said New Securities on the same terms and at the same price at which the Company proposes to sell the New Securities. The pro rata share of each Investor, for purposes of this
right of first refusal, is (except as set forth in paragraph 5(a)(v) below) the ratio of the total number of shares of Common Stock held by such Investor, including any shares of Common Stock into which shares of Preferred Stock held by such
Investor are convertible, to the total number of shares of Common Stock outstanding immediately prior to the issuance of the New Securities (including any shares of Common Stock into which outstanding shares of Preferred Stock are convertible).

  

 14 

 (1) “New Securities” shall mean any capital stock of the Company, whether now
authorized or not, and any rights, options or warrants to purchase said capital stock, and securities of any type whatsoever that are, or may become, convertible into said capital stock; provided that “New Securities” does not include
(i) the Shares purchased under the Purchase Agreement or the Conversion Stock, (ii) shares of Series A Preferred Stock or Series B Preferred Stock or Common Stock issuable upon conversion thereof outstanding as of the date hereof,
(iii) all shares of Common Stock, options, warrants and the Common Stock issuable upon the exercise thereof issued and outstanding on the date hereof; (iv) all shares of Common Stock into which the shares of Preferred Stock are
convertible; (v) up to 3,616,406 shares of Common Stock or other securities (including, but not limited to, options to purchase Common Stock or any other securities) or warrants issuable to employees, officers, consultants or directors of, or
licensors of technology to, the Company, under any agreement, arrangement or plan, including any incentive stock plan, approved by the Board of Directors of the Company, or such additional shares, options, warrants, or other securities (including,
but not limited to, options to purchase Common Stock or any other securities) issuable to employees, officers, consultants or directors of, or licensors of technology to, the corporation, under any agreement, arrangement or plan, including any
incentive stock plan, approved by a majority of the Preferred Directors; (vi) all shares of Common Stock or other securities, or options or warrants to purchase Common Stock or any such other securities issued or to be issued to suppliers,
lessors or lenders to the Company, pursuant to any plan or arrangement approved by the Board of Directors of the Company and a majority of the Preferred Directors; (vii) up to 23,755,471 shares of Series C Preferred Stock or the Common Stock
issuable upon conversion thereof; and (viii) up to $8,000,000.00 in convertible promissory notes or the Common Stock issuable upon conversion thereof. 
 (ii) In the event the Company proposes to undertake an issuance of New Securities, it shall give to the Investors written notice (the “Notice”) of its intention, describing the type of New Securities, the
price, the terms upon which the Company proposes to issue the same, and a statement as to the number of days from receipt of such Notice within which the Investors must respond to such Notice. The Investors shall have thirty (30) days from the
date of receipt of the Notice to purchase any or all of the New Securities for the price and upon the terms specified in the Notice by giving written notice to the Company and stating therein the quantity of New Securities to be purchased and
forwarding payment for such New Securities to the Company if immediate payment is required by such terms, or in any event no later than thirty (30) days after the date of receipt of the Notice. 
 (iii) In the event the Investors fail to exercise in full the right of first offer within said thirty (30) day period, the Company
shall have ninety (90) days thereafter to sell or enter into an agreement (pursuant to which the sale of New Securities covered thereby shall be closed, if at all, within thirty (30) days from date of said agreement) to sell the New
Securities respecting which the Investors’ rights were not exercised, at a price and upon general terms no more favorable to the Investors thereof than specified in the Notice. In the event the Company has not sold the New Securities within
said ninety (90) day period (or sold and issued New Securities in accordance with the foregoing within thirty (30) days from the date of said agreement), the Company shall not thereafter issue or sell any New Securities without first
offering such securities to the Investors in the manner provided above. 
  

 15 

 (iv) The right of first offer granted under this Section 5(a) shall expire upon:

 (1) the date upon which a registration statement filed by the Company under the Securities Act (other than a registration
of securities in a Rule 145 transaction or with respect to an employee benefit plan) in connection with a Qualified Public Offering first becomes effective and the securities registered thereunder are sold; or 
 (2) for each Investor or Holder the date on which such Investor or Holder, together with its affiliates, no longer holds at least 500,000
Shares or equivalent shares of Registrable Securities (or any combination thereof). 
 (v) The right of first offer granted
under this Section 5(a) is assignable by an Investor or Holder to any transferee of at least 500,000 Shares or equivalent number of shares of Registrable Securities (or any combination thereof). 
 6. Covenants of the Company. The Company hereby covenants to the Investors the following: 
 (a) The Board shall meet not less frequently than quarterly until otherwise agreed by Investors holding at least sixty-six and two-thirds
percent (66-2/3%) of the then outstanding shares of Preferred Stock. The documented reasonable travel expenses of the directors incurred in attending Board meetings shall be paid or reimbursed promptly by the Company. The Company shall prepare and
submit to the Board for review ninety (90) days prior to the end of each fiscal year a preliminary operating budget and plan respecting the next fiscal year. 
 7. General Provisions. 
 (a) Amendment and Waiver. Any term of this Agreement
may be amended and the observance of any term of this Agreement may be waived (either generally or in a particular instance and either retroactively or prospectively), only with the written consent of the Company and the holders of a majority of the
shares of the Registrable Securities issued or issuable upon conversion of the Preferred Stock of the Company; provided however that any purchaser of Series C Preferred Stock may be made a party to this Agreement without necessitating further
amendment hereto. Any amendment or waiver effected in accordance with this Section 8(a) shall be binding upon each holder of any Shares or Registrable Securities purchased under this Agreement at the time outstanding, each future holder of all
such securities and the Company. 
 (b) Amendment and Restatement. This Amendment hereby amends and restates the Prior
Agreement and shall be effective upon the execution of this Agreement by the Company and the holders of a majority of the shares of Registrable Securities. 
 (c) Governing Law. This Agreement shall be governed by and construed under the laws of the State of Delaware. 
  

 16 

 (d) Successors and Assigns. Except as otherwise expressly provided, the provisions
of this Agreement shall inure to the benefit of, and be binding upon, the successors, assigns, heirs, executors, and administrators of the parties. 
 (e) Severability. In case any provision of this Agreement becomes or is declared by a court of competent jurisdiction to be unenforceable, this Agreement shall continue in full force and effect without said
provision; provided, however, that no such severability shall be effective if it materially changes the economic benefit of this Agreement to any party. 
 (f) Notices. All notices and other communications required or permitted hereunder shall be in writing and shall be deemed effectively given upon personal delivery or facsimile to the party to be notified or
forty-eight (48) hours after deposit with the United States Post Office, by first class mail, postage prepaid, addressed: (a) if to the Investors, at the Investors’ address as set forth on the signature page, or at such other address
as the Investors shall have furnished to the Company in writing, or (b) if to the Company, at its current address or at such other address as the Company shall have furnished to the Investors in writing. 
 (g) Counterparts. This Agreement may be executed in any number of counterparts, each of which is an original, and all of which
together shall constitute one instrument. 
 (h) Aggregation of Stock. All Shares held or acquired by affiliated
entities or persons shall be aggregated together for the purpose of determining the availability of any rights under this Agreement. 
  

 17 

 IN WITNESS WHEREOF, this Fourth Amended and Restated Investors’ Rights Agreement has been executed
as of the date first above written. 
  

			
	COMPANY:
	
	 SENORX, INC.

		
	By:	 	/s/ Lloyd Malchow
		 	 Lloyd Malchow, President and Chief
 Executive
Officer

  

 SenoRx, Inc. 
 Fourth Amended and Restated Investors’ Rights Agreement 

			
	INVESTORS:
	MPM BIOVENTURES II, L.P.
	
	By: MPM Asset Management II, L.P., its
General Partner
	By: MPM Asset Management II LLC, its
General Partner
		
	By:	 	/s/ Kurt Wheeler
		 	Kurt Wheeler, Managing Member
	
	MPM BIOVENTURES II-QP, L.P.
	
	By: MPM Asset Management II, L.P., its
General Partner
	By: MPM Asset Management II LLC, its
General Partner
		
	By:	 	/s/ Kurt Wheeler
		 	Kurt Wheeler, Managing Member
	
	 MPM BIOVENTURES GMBH & CO.
 PARALLEL-BETEILIGUNGS KG

	
	By: MPM Asset Management II, L.P., in its capacity as the Special Limited Partner
	By: MPM Asset Management II LLC, its
General Partner
		
	By:	 	/s/ Kurt Wheeler
		 	Kurt Wheeler, Managing Member
	
	MPM ASSET MANAGEMENT INVESTORS 2001 LLC
		
	By:	 	/s/ Kurt Wheeler
		 	Kurt Wheeler, Managing Member

  

 SenoRx, Inc. 
 Fourth Amended and Restated Investors’ Rights Agreement 

			
	DOMAIN PARTNERS IV, L.P.
	By:	 	One Palmer Square Associates IV, L.L.C.
		 	its General Partner
		
	By:	 	/s/    Kathleen K. Schoemaker
		 	Kathleen K. Schoemaker
		 	Managing Member
	
	DP IV ASSOCIATES, L.P.
	By:	 	One Palmer Square Associates IV, L.L.C.
		 	its General Partner
		
	By:	 	/s/    Kathleen K. Schoemaker
		 	Kathleen K. Schoemaker
		 	Managing Member

  

 SenoRx, Inc. 
 Fourth Amended and Restated Investors’ Rights Agreement 

			
	 MEDICUS VENTURE PARTNERS X
 A California
Limited Partnership

		
	 By:
	 	Medicus Management Partners, General Partner
		
	 By:
	 	/s/ Fred Dotzler
		 	Frederick J. Dotzler, General Partner
	
	/s/ Fred Dotzler
	Frederick J. Dotzler

  

 SenoRx, Inc. 
 Fourth Amended and Restated Investors’ Rights Agreement 

			
	De Novo Ventures I, LP
		
	By:	 	De Novo Management LLC
		 	Its General Partner
		
	By:	 	/s/ Fred Dotzler
		 	Fred Dotzler
		 	Managing Director
	
	De Novo (Q) Ventures I, LP
		
	By:	 	De Novo Management LLC
		 	Its General Partner
		
	By:	 	/s/ Fred Dotzler
		 	Fred Dotzler
		 	Managing Director

  

 SenoRx, Inc. 
 Fourth Amended and Restated Investors’ Rights Agreement 

			
	
	/s/ Lloyd Malchow
	Lloyd Malchow

  

 SenoRx, Inc. 
 Fourth Amended and Restated Investors’ Rights Agreement 

			
	HUTTON LIVING TRUST
		
	By:	 	/s/ Wende Hutton
		
	Name:	 	  
		
	Title:	 	  

  

 SenoRx, Inc. 
 Fourth Amended and Restated Investors’ Rights Agreement 

 EXHIBIT A 
 SCHEDULE OF INVESTORS 
 Name and Address 
 MPM BIOVENTURES II, L.P. 
 One Cambridge Center, 9th Floor, 
 Cambridge, MA 02142 
 Attn: Kurt Wheeler 
 MPM BIOVENTURES II-QP, L.P. 
 One Cambridge Center, 9th Floor, 
 Cambridge, MA 02142 
 Attn: Kurt Wheeler 
 MPM BIOVENTURES GMBH & CO. PARALLEL-BETEILIGUNGS KG 
 One Cambridge
Center, 9th Floor, 
 Cambridge, MA 02142 
 Attn: Kurt Wheeler

 MPM ASSET MANAGEMENT INVESTORS 2001 LLC 
 One Cambridge
Center, 9th Floor, 
 Cambridge, MA 02142 
 Attn: Kurt Wheeler

 THE CIT GROUP/VENTURE CAPITAL, INC. 
 44 Whippany Road, Suite
140 
 Morristown, NJ 07960 
 Attn: James Glasheen 
 DOMAIN ASSOCIATES IV, L.P. 
 One Palmer Square 
 Princeton, NJ 08542 
 Attn: Kathleen K. Schoemaker 
 DP IV ASSOCIATES, L.P. 
 One Palmer Square 
 Princeton, NJ 08542 
 Attn: Kathleen K. Schoemaker 
  

 SenoRx, Inc. 
 Fourth Amended and Restated Investors’ Rights Agreement 

 MEDICUS VENTURE PARTNERS X 
 2882 Sand Hill Road 
 Suite 116 
 Menlo Park, CA 94025 
 Attn: Fred Dotzler 
 MAYFIELD IX 
 2800 Sand Hill Road 
 Suite 250 
 Menlo Park, CA 94025 
 Attn: Wende Hutton 
 MAYFIELD ASSOCIATES FUND IV 
 2800 Sand Hill Road 
 Suite 250 
 Menlo Park, CA 94025 
 Attn: Wende Hutton 
 Lloyd Malchow 
 28481 Via Mambrino 
 San Juan Capistrano, CA 92675 
 David Kelter 
 11430 Meadow Grass Lane 
 San Diego, CA 92128 
 Adam Ventures L.P. 
 650 Page Mill Road 
 Palo Alto, CA 94036 
 Michael Fenoglio 
 1601 E. 19th Avenue 
 Suite 4500 
 Denver, CO 80218 
 Phillip Z. Israel 
 The Breast Center 
 702 Canton Road 
 Marietta, GA 30060 
 Roger Jackman 
 Palo Alto Medical Foundation 
 Department of Radiology 
 300 Homer Avenue 
 Palo Alto, CA 94301 
  

 SenoRx, Inc. 
 Fourth Amended and Restated Investors’ Rights Agreement 

 William McMurray Family Trust U/A dtd 5/8/91 
 15418 Sutton Street 
 Sherman Oaks, CA 91403 
 Morgan Nields 
 12300 N. Grant Street 
 Denver, CO 80241 
 RIA Partners 
 3333 South Bannock, Ste. 600 
 Englewood, CO 80110 
 Attn: Jeff Morey 
 Nancy Rochford and Kaukab N. Chaudhry 
 114 E. 90th Street 
 New York, NY 10128 
 Frederick J. Dotzler 
 19438 Burgundy Way 
 Saratoga, CA 95070 
 VENTURE LENDING & LEASING IV, LLC 
 2010 North First Street 
 Suite 310 
 San Jose, CA 95131 
 Hutton Living Trust 
 2 Santiago Avenue 
 Atherton, CA 94027 
  

 SenoRx, Inc. 
 Fourth Amended and Restated Investors’ Rights Agreement

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