Document:

Letter Agreement

 Exhibit 10.38 
 [CombinatoRx Letterhead] 
 August 4, 2008 
 BioMedical Sciences Investment Fund Pte Ltd 
 20 Biopolis Way 
 #09-01 Centros 
 Singapore 138668 
 Attention: Chief Executive Officer 
 Re: Agreement Regarding Exercise of Parent Share Repurchase Option 
 Ladies and Gentlemen: 
 CombinatoRx (Singapore) Pte Ltd (the
“Company”), Biomedical Sciences Investment Fund Pte Ltd (the “Investor”) and CombinatoRx, Incorporated (the “Parent”), are parties to a Subscription and Shareholders Agreement, dated August 19, 2005 (the
“SSA”) and a Swap-Up Agreement, dated August 30, 2005 (the “Swap-Up Agreement”). Under Section 7.1 of the Swap-Up Agreement, Investor granted Parent the option, exercisable at any time, to purchase all of the
Investor’s preferred shares in the Company for a cash purchase price (the “Parent Share Repurchase Option”). By executing this letter agreement, the Parent hereby agrees not to exercise the Parent Share Repurchase Option under the
Swap-Up Agreement until on or after December 31, 2009, provided, however, the Parent may exercise the Parent Share Purchase Option after the Investor has breached a material obligation under the SSA and related agreements, or after an Organic
Change of the Parent, as defined in the Swap-Up Agreement. 
  

			
	Sincerely,
	
	COMBINATORX, INCORPORATED
		
	By:	 	 /s/ Alexis Borisy

	Name:	 	Alexis Borisy
	Title:	 	President & CEO
	
	COMBINATORX (SINGAPORE) PTE LTD
		
	By:	 	 /s/ Ralf Altmeyer

	Name:	 	Ralf Altmeyer
	Title:	 	President
	
	BIOMEDICAL SCIENCES INVESTMENT FUND PTE LTD
		
	By:	 	 /s/ Chu Swee Yeok

	Name:	 	Chu Swee Yeok
	Title:	 	Director
		
	Date:	 	 August 5, 2008Form of Indemnification Agreement

 EXHIBIT 10.7 
 INDEMNIFICATION AGREEMENT 
 THIS INDEMNIFICATION AGREEMENT is made and entered into as of this
     day of                 , (the “Agreement”), by and between SVB Financial Group, a Delaware corporation
(the “Company”), and                      (the “Indemnitee”). 
 WHEREAS, Indemnitee is either a member of the board of directors of the Company (the “Board of Directors”) or an officer of the Company,
or both, and in such capacity or capacities, or otherwise as an Agent (as defined below) of the Company, is performing a valuable service for the Company; 
 WHEREAS, the Company desires the benefits of having Indemnitee serve as a member of the Board of Directors or an officer, or both, or an Agent, secure in the knowledge that any expenses, liability and/or losses
incurred by him or her in his or her good faith service to the Company will be borne by the Company or its successors and assigns; 
 WHEREAS, Indemnitee is willing to serve or continue to serve in his or her position with the Company, or to take on additional service for or on behalf of the Company, only on the condition that he or she be indemnified as herein provided;

 WHEREAS, the Company is aware that because of the increased exposure to litigation costs and risks resulting from service to corporations,
talented and experienced persons are increasingly reluctant to serve or continue to serve as directors or executive officers of corporations unless they are protected by comprehensive liability insurance and indemnification; 
 WHEREAS, the Company and Indemnitee recognize the increasing difficulty in obtaining liability insurance for directors, officers and agents of a
corporation at reasonable cost; and 
 WHEREAS, the Company’s Restated Certificate of Incorporation (the “Certificate”)
allows and requires the Company to indemnify its directors, officers and agents to the maximum extent permitted under Delaware law. 
 NOW,
THEREFORE, in consideration of the premises and the covenants in this Agreement, and of Indemnitee continuing to serve the Company as an Agent and intending to be legally bound hereby, the Company and Indemnitee hereby agree as follows: 

1. Definitions. For purposes of this Agreement: 
 1.1 “Agent” shall mean any person who is or was, or who has consented to serve as a, director, officer, employee or agent of the Company or a subsidiary of the Company whether serving in such capacity
or as a director, officer, employee, agent, fiduciary, joint venturer, partner, member, manager or other official of another corporation, partnership, limited liability company, joint venture, trust or other enterprise (including, without
limitation, an employee 

 
benefit plan) either at the request of, for the convenience of, or otherwise to benefit the Company or a subsidiary of the Company. 
 1.2 “Change of Control” shall mean the occurrence of any of the following events after the date of this Agreement:

 (a) A change in the composition of the Board of Directors, as a result of which fewer than two-thirds of the incumbent
directors are directors who either (i) had been directors of the Company 24 months prior to such change (the “Original Directors”) or (ii) were elected, or nominated for election, to the Board of Directors with the
affirmative votes of at least a majority in the aggregate of the Original Directors who were still in office at the time of the election or nomination and directors whose election or nomination was previously so approved (the “continuing
directors”); 
 (b) Both (i) any “person” (as such term is used in sections 13(d) and 14(d) of the
Securities Exchange Act of 1934, as amended (the “Exchange Act”)) through the acquisition or aggregation of securities is or becomes the beneficial owner, directly or indirectly, of securities of the Company representing 20 percent
or more of the combined voting power of the Company’s then outstanding securities eligible to vote for the election of the Board of Directors; and (ii) the beneficial ownership by such person of securities representing such percentage has
not been approved by a majority of the “continuing directors” (as defined above); 
 (c) Any “person” is
or becomes the “beneficial owner” (as defined in Rule 13d-3 under the Exchange Act), directly or indirectly, of securities of the Company representing at least 50% of the total voting power represented by the Company’s then
outstanding voting securities; 
 (d) The stockholders of the Company approve a merger or consolidation of the Company with
any other corporation, if such merger or consolidation would result in the voting securities of the Company outstanding immediately prior thereto representing (either by remaining outstanding or by being converted into voting securities of the
surviving entity) 50% or less of the total voting power represented by the voting securities of the Company or such surviving entity outstanding immediately after such merger or consolidation; or 
 (e) The stockholders of the Company approve (i) a plan 

  

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of complete liquidation of the Company or (ii) an agreement for the sale or disposition by the Company of all or substantially all of the Company’s
assets. 
 Any other provision of this Section 1.2 notwithstanding, the term “Change of Control” shall
not include a transaction, if undertaken at the election of the Company, the result of which is to sell all or substantially all of the assets of the Company to another corporation (the “surviving corporation”); provided that
the surviving corporation is owned directly or indirectly by the stockholders of the Company immediately following such transaction in substantially the same proportions as their ownership of the Company’s common stock immediately preceding
such transaction; and provided, further, that the surviving corporation expressly assumes this Agreement. 
 1.3
“Delaware Law” means the Delaware General Corporation Law, as amended and in effect from time to time or any successor or other statutes of Delaware having similar import and effect. 
 1.4 “Disinterested Director” shall mean a director of the Company who is not and was not a party to the Proceeding in
respect of which indemnification is being sought by Indemnitee. 
 1.5 “Expenses” shall mean, all reasonable
attorneys’ fees, retainers, court costs, transcript costs, fees and costs of experts, witness fees, travel expenses, duplicating costs, printing and binding costs, telephone charges, postage, delivery service fees, and all other disbursements
or expenses of the types customarily incurred in connection with prosecuting, defending, preparing to prosecute or defend, investigating, being or preparing to be a witness in, or otherwise participating in, a Proceeding. Expenses also include
(i) Expenses incurred in connection with any appeal resulting from any Proceeding, including without limitation the premium, security for, and other costs relating to any cost bond, supersedeas bond or other appeal bond or their equivalent, and
(ii) for purposes of Section 7.6, Expenses incurred by Indemnitee in connection with the interpretation, enforcement or defense of Indemnitee’s rights under this Agreement or under any directors’ and officers’ liability
insurance policies maintained by the Company. Expenses, however, shall not include amounts paid in settlement by Indemnitee or the amount of judgments or fines against Indemnitee. 
 1.6 “Independent Legal Counsel” shall mean a law firm or a member of a law firm selected by the Company and approved by
Indemnitee (which approval shall not be unreasonably withheld) or, if there has been a Change of Control, selected by Indemnitee and approved by the Company (which approval shall not be unreasonably withheld), that neither is presently nor in the
past five years has been retained to represent: (a) the Company or any of its subsidiaries or affiliates, or Indemnitee or any corporation of which Indemnitee was or is a director, officer, employee or agent, or any subsidiary or affiliate of
such a corporation, in any matter material to either party, or (b) any other party to the Proceeding giving rise to a claim for indemnification hereunder. Notwithstanding the foregoing, the term “Independent Legal Counsel”
shall not include any person who, under the applicable standards of professional conduct then prevailing, 

  

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would have a conflict of interest in representing either the Company or Indemnitee in an action to determine Indemnitee’s right to indemnification under
this Agreement. 
 1.7 “Liabilities” shall mean liabilities of any type whatsoever, including, but not
limited to, judgments (including punitive and exemplary damages), fines, ERISA or other excise taxes and penalties, and amounts paid in settlement (including all interest, assessments or other charges paid or payable in connection with or in respect
of any of the foregoing). 
 1.8 “Proceeding” shall mean any pending, threatened or completed action, claim,
hearing, suit, arbitration, or any other proceeding, whether civil, criminal, arbitrative, administrative, investigative, or any alternative dispute resolution mechanism, whether formal or informal, including without limitation any such Proceeding
brought by or in the right of the Company in which Indemnitee was, is or will be involved as a party, a potential party, a non-party witness or otherwise by reason of the fact that Indemnitee is or was an Agent of the Company. 
 2. Employment Rights and Duties. Subject to any other obligations imposed on either of the parties by contract or by law, and with the
understanding that this Agreement is not intended to confer employment rights on either party which they did not possess on the date of its execution, Indemnitee agrees to serve as a director or officer so long as he or she is duly appointed or
elected and qualified in accordance with the applicable provisions of the Certificate and Bylaws (the “Bylaws”) of the Company or any subsidiary of the Company and until such time as he or she resigns or fails to stand for election
or until his or her employment terminates. Indemnitee may from time to time also perform other services at the request, or for the convenience of, or otherwise benefiting the Company. Indemnitee may at any time and for any reason resign or be
removed from such position (subject to any other contractual obligation or other obligation imposed by operation of law), in which event the Company shall have no obligation under this Agreement to continue Indemnitee in any such position.

 3. Indemnification. Subject to the limitations set forth herein and in Section 9 hereof, the Company hereby agrees to
indemnify Indemnitee as follows: 
 3.1 Indemnity in Third-Party Proceedings. The Company shall indemnify Indemnitee in
accordance with the provisions of this Section 3.1 if Indemnitee is, or is threatened to be made, a party to or a participant in any Proceeding, other than a Proceeding by or in the right of the Company to procure a judgment in its favor.
Pursuant to this Section 3.1, Indemnitee shall be indemnified to the fullest extent permitted by applicable law against all Expenses, judgments, fines and amounts paid in settlement actually and reasonably incurred by Indemnitee or on his or
her behalf in connection with such Proceeding or any claim, issue or matter therein, if Indemnitee acted in good faith and in a manner he or she reasonably believed to be in or not opposed to the best interests of the Company and, with respect to
any criminal action or proceeding, had no reasonable cause to believe that his or her conduct was unlawful. 
  

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 3.2 Indemnity in Proceedings by or in the Right of the Company. The Company shall
indemnify Indemnitee in accordance with the provisions of this Section 3.2 if Indemnitee is, or is threatened to be made, a party to or a participant in any Proceeding by or in the right of the Company to procure a judgment in its favor.
Pursuant to this Section 3.2, Indemnitee shall be indemnified to the fullest extent permitted by applicable law against all Expenses actually and reasonably incurred by Indemnitee or on Indemnitee’s behalf in connection with such
Proceeding or any claim, issue or matter therein, if Indemnitee acted in good faith and in a manner he or she reasonably believed to be in or not opposed to the best interests of the Company. No indemnification for Expenses shall be made under this
Section 3.2 in respect of any claim, issue or matter as to which Indemnitee shall have been adjudged by a court of competent jurisdiction to be liable to the Company, unless and only to the extent that the Delaware Court of Chancery or any
court in which the Proceeding was brought shall determine upon application that, despite the adjudication of liability but in view of all the circumstances of the case, Indemnitee is fairly and reasonably entitled to indemnification for such
expenses as the Delaware Court of Chancery or such other court shall deem proper. 
 In addition to, and not as a limitation
of, the foregoing, the rights of indemnification of Indemnitee provided under this Agreement shall include those rights set forth in Sections 4, 5 and 7 below. Notwithstanding the foregoing, the Company shall be required to indemnify Indemnitee in
connection with a Proceeding commenced by Indemnitee (other than a Proceeding commenced by Indemnitee to enforce Indemnitee’s rights under this Agreement) only if the commencement of such Proceeding was authorized by the Board of Directors.
Further, notwithstanding any other provision of this Agreement, to the extent that Indemnitee is, by reason of his or her role as an Agent, a witness in any Proceeding to which Indemnitee is not a party, Indemnitee shall be indemnified to the
fullest extent permitted by applicable law against all Expenses actually and reasonably incurred by Indemnitee or on Indemnitee’s behalf in connection therewith. 
 4. Payment of Expenses. 
 4.1 All Expenses incurred by or on behalf of Indemnitee
shall be advanced by the Company to Indemnitee within 20 days after the receipt by the Company of a written request for such advance which may be made from time to time, whether prior to or after final disposition of a Proceeding (unless there has
been a final determination by a court of competent jurisdiction or decision of an arbitrator that Indemnitee is not entitled to be indemnified for such Expenses). Indemnitee’s entitlement to advancement of Expenses shall include those incurred
in connection with any Proceeding by Indemnitee seeking a determination, an adjudication or an award in arbitration pursuant to this Agreement. The written requests shall reasonably evidence the Expenses incurred by Indemnitee in connection
therewith. In the event that such written request shall be accompanied by an affidavit of counsel to Indemnitee to the effect that such counsel has 

  

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reviewed such expenses and that such expenses are reasonable in such counsel’s view, then such expenses shall be deemed reasonable in the absence of
clear and convincing evidence to the contrary. Indemnitee hereby undertakes to repay to the Company the amounts advanced if it shall ultimately be determined that Indemnitee is not entitled to be indemnified pursuant to the terms of this Agreement.

 4.2 Notwithstanding any other provision in this Agreement, to the extent that Indemnitee has been successful on the merits
or otherwise in defense of any Proceeding, Indemnitee shall be indemnified against all Expenses actually and reasonably incurred by Indemnitee in connection therewith. 
 5. Procedure for Determination of Entitlement to Indemnification. 
 5.1 Whenever
Indemnitee believes that Indemnitee is entitled to indemnification pursuant to this Agreement, Indemnitee shall submit a written request for indemnification (the “Indemnification Request”) to the Company to the attention of the
President. This request shall include documentation or information which is necessary for the determination of entitlement to indemnification and which is reasonably available to Indemnitee. In any event, Indemnitee shall submit Indemnitee’s
claim for indemnification within a reasonable time, not to exceed five (5) years after any judgment, order, settlement, dismissal, arbitration award, conviction, acceptance of a plea of nolo contendere or its equivalent, or final
termination, whichever is the later date for which Indemnitee requests indemnification. The President shall, promptly upon receipt of Indemnitee’s request for indemnification, advise the Board of Directors in writing that Indemnitee has made
such request for indemnification. Determination of Indemnitee’s entitlement to indemnification shall be made no later than 60 days after receipt of the Indemnification Request, provided that any request for indemnification for Liabilities,
other than amounts paid in settlement, shall have been made after a determination thereof in a Proceeding. 
 5.2 The Company
shall be entitled to select the forum in which Indemnitee’s entitlement to indemnification will be heard; provided, however, that if there is a Change of Control of the Company, Independent Legal Counsel shall determine whether
Indemnitee is entitled to indemnification. The Company shall notify Indemnitee in writing as to the forum selected, which selection shall be any one of the following: 
 (a) A majority vote of Disinterested Directors even though less than a quorum. 
 (b) A written opinion of Independent Legal Counsel, a copy of which shall be furnished to the Company, the Indemnitee and each member of
the Board of Directors. 
  

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 (c) A majority vote of the stockholders of the Company at a meeting at which a quorum is
present, with the shares owned by the person to be indemnified not being entitled to vote thereon. 
 (d) The court in which
the Proceeding is or was pending upon application by Indemnitee. 
 The Company agrees to bear any and all Expenses incurred
by Indemnitee or the Company in connection with the determination of Indemnitee’s entitlement to indemnification in any of the above forums. 
 6. Presumptions and Effect of Certain Proceedings. No initial finding by the Board of Directors, its counsel, Independent Legal Counsel, arbitrators or the stockholders shall be effective to deprive Indemnitee of the protection of
this indemnity, nor shall a court or other forum to which Indemnitee may apply for enforcement of this indemnity give any weight to any such adverse finding in deciding any issue before it. Upon making a request for indemnification, Indemnitee shall
be presumed to be entitled to indemnification under this Agreement and the Company shall have the burden of proof to overcome that presumption in reaching any contrary determination. No initial determination, in whole or in part, that Indemnitee is
not entitled to indemnification shall create a presumption in any judicial proceeding or arbitration that Indemnitee has not met the applicable standard of conduct for, or is otherwise not entitled to, indemnification. If the person or persons
empowered to make the determination shall have failed to make the requested determination within 60 days after any judgment, order, settlement, dismissal, arbitration award, conviction, acceptance of a plea of nolo contendere or its
equivalent, or other disposition or partial disposition of any Proceeding, or any other event which could enable the Company to determine the Indemnitee’s entitlement to indemnification, the required determination of entitlement to
indemnification shall be deemed to have been made and the Indemnitee shall be absolutely entitled to indemnification under this Agreement, absent (a) misrepresentation or omission of a material fact by the Indemnitee in the request for
indemnification or (b) a specific finding that all or any part of such indemnification is expressly prohibited by law or this Agreement. The termination of any Proceeding by judgment, order, settlement, arbitration award or conviction, or upon
a plea of nolo contendere or its equivalent, shall not, of itself, (i) adversely affect the rights of Indemnitee to indemnification except as indemnification may be expressly prohibited under this Agreement, or (ii) establish a
presumption with regard to any factual matter relevant to determining Indemnitee’s rights to indemnification hereunder. 
 7.
Remedies of Indemnitee in Cases of Determination Not to Indemnify or to Advance Expenses. 
 7.1 In the event that
(a) an initial determination is made that Indemnitee is not entitled to indemnification, (b) advances for Expenses are not made when and as required by this Agreement, (c) payment has not been timely made following a determination of
entitlement to indemnification pursuant to this Agreement, or (d) Indemnitee otherwise seeks enforcement of this Agreement, Indemnitee shall be entitled to a final adjudication in an appropriate court of the State of Delaware of his or her
entitlement to such indemnification or advance. 

  

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Alternatively, unless court approval is required by law for the indemnification sought by Indemnitee, Indemnitee at Indemnitee’s option may seek an
award in arbitration to be conducted by a single arbitrator pursuant to the commercial arbitration rules of the American Arbitration Association now in effect, which award is to be made within 90 days following the filing of the demand for
arbitration. Except as set forth herein, the provisions of Delaware law shall apply to any such arbitration. The Company shall not oppose Indemnitee’s right to seek any such adjudication or arbitration award. In any such proceeding or
arbitration, Indemnitee shall be presumed to be entitled to indemnification and advancement of Expenses under this Agreement and the Company shall have the burden of proof to overcome that presumption. 
 7.2 In the event that a determination that Indemnitee is not entitled to indemnification, in whole or in part, has been made pursuant to
Section 5 hereof, the decision in the judicial proceeding or arbitration provided in Section 7.1 shall be made de novo and Indemnitee shall not be prejudiced by reason of an initial determination that Indemnitee is not entitled to
indemnification. 
 7.3 If an initial determination is made or deemed to have been made pursuant to the terms of this
Agreement that Indemnitee is entitled to indemnification, the Company shall be bound by such determination in the absence of (a) a misrepresentation or omission of a material fact by Indemnitee in the request for indemnification or (b) a
specific finding (which has become final) by a court of competent jurisdiction that all or any part of such indemnification is expressly prohibited by law. 
 7.4 The Company and Indemnitee agree herein that a monetary remedy for breach of this Agreement, at some later date, will be inadequate, impracticable and difficult of proof, and further agree that such breach would
cause Indemnitee irreparable harm. Accordingly, the Company and Indemnitee agree that Indemnitee shall be entitled to temporary and permanent injunctive relief to enforce this Agreement without the necessity of proving actual damages or irreparable
harm. The Company and Indemnitee further agree that Indemnitee shall be entitled to such injunctive relief, including temporary restraining orders, preliminary injunctions and permanent injunctions, without the necessity of posting bond or other
undertaking in connection therewith. Any such requirement of bond or undertaking is hereby waived by the Company, and the Company acknowledges that in the absence of such a waiver, a bond or undertaking may be required by the court. 
 7.5 The Company shall be precluded from asserting that the procedures and presumptions of this Agreement are not valid, binding and
enforceable. The Company shall stipulate in any such court or before any such arbitrator that the Company is bound by all the provisions of this Agreement and is precluded from making any assertion to the contrary. 
  

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 7.6 All Expenses incurred by Indemnitee in connection with his or her request for
indemnification under, seeking enforcement of, or recovery of damages for breach of, this Agreement shall be borne and advanced by the Company, to the extent not prohibited by law. 
 8. Other Rights to Indemnification. Indemnitee’s rights of indemnification and advancement of Expenses provided by this Agreement shall not
be deemed exclusive of any other rights to which Indemnitee may now or in the future be entitled under applicable law, the Certificate, the Bylaws, agreement, vote of stockholders or Disinterested Directors, insurance or other financial
arrangements, or otherwise. 
 9. Limitations on Indemnification. No indemnification pursuant to Section 3 shall be paid by the
Company nor shall Expenses be advanced pursuant to Section 4: 
 9.1 Insurance. To the extent to which payment has
actually been made to or on behalf of Indemnitee under any statute, insurance policy, indemnity provision, vote or otherwise, except with respect to any excess beyond the amount so paid. Notwithstanding the availability of such insurance, Indemnitee
also may claim indemnification from the Company pursuant to this Agreement by assigning to the Company any claims under such insurance to the extent Indemnitee is paid by the Company. Indemnitee shall reimburse the Company for any sums he or she
receives as indemnification from other sources to the extent of any amount paid to him or her for that purpose by the Company; 
 9.2 Section 16(b). On account and to the extent of any wholly or partially successful claim against Indemnitee for an accounting of profits made from the purchase or sale by Indemnitee of securities of the Company in violation
of the provisions of Section 16(b) of the Exchange Act or similar provisions of any federal, state or local statutory law; 
 9.3 Section 304 Forfeiture. On account and to the extent of any wholly or partially successful claim against Indemnitee that such amounts include amounts paid in bonus or other incentive-based or equity-based compensation, or
profits from the sale of securities, that the Indemnitee is required to reimburse to the Company under Section 304 of the Sarbanes-Oxley Act of 2002; 
 9.4 Unauthorized Settlements. Provided there has been no Change of Control, for Liabilities in connection with Proceedings settled without the Company’s consent, which consent, however, shall not be
unreasonably withheld; 
 9.5 Unlawful Indemnification. To the extent it would be otherwise prohibited by law, if so
established by a judgment or other final adjudication adverse to Indemnitee; 
 9.6 Indemnitee’s Proceedings.
Except as otherwise expressly provided in this Agreement, in connection with all or any part of a Proceeding which is initiated or maintained by or on behalf of Indemnitee, or any Proceeding by Indemnitee against the Company or its directors,
officers, employees or other 

  

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Agents, unless (a) such indemnification is expressly required to be made by Delaware Law, (b) the Proceeding was authorized by a majority of the
Disinterested Directors, (c) there has been a Change of Control, or (d) such indemnification is provided by the Company, in its sole discretion, pursuant to the powers vested in the Company under Delaware Law; 
 9.7 Actions Initiated by Federal Banking Agency. If and to the extent it is sustained in connection with an administrative or civil
enforcement action which is initiated by a federal banking agency and results in a final adjudication or finding against Indemnitee; or 
 9.8 Indemnification Prohibited by FDIC or Federal Banking Law. If and to the extent that, on the date thereof, it is a prohibited indemnification payment under the regulations and the general policy of the
Federal Deposit Insurance Corporation (including, without limitation, 12 C.F.R. Part 359.0 et seq.) or federal banking law (including, without limitation, 12 U.S.C. Section 1828(k)), as both are amended and in effect on the date of such
payment. 
 10. Duration and Scope of Agreement; Binding Effect. This Agreement shall continue so long as Indemnitee shall be subject
to any possible Proceeding subject to indemnification by reason of the fact that he or she is or was an Agent and shall be applicable to Proceedings commenced or continued after execution of this Agreement, whether arising from acts or omissions
occurring before or after such execution. This Agreement shall be binding upon the Company and its successors and assigns (including any direct or indirect successor by purchase, merger, consolidation or otherwise to all or substantially all of the
business or assets of the Company) and shall inure to the benefit of Indemnitee and his or her spouse, assigns, heirs, devisees, executors, administrators and other legal representatives. The Company shall require and cause any successor (whether
direct or indirect by purchase, merger, consolidation or otherwise) to all or substantially all of the Company’s business or assets by written agreement in form and substance reasonably satisfactory to the Indemnitee, expressly to assume and
agree to perform this Agreement in the same manner and to the same extent that the Company would be required to perform if no such succession had taken place. 
 11. Notice by Indemnitee and Defense of Claims. Indemnitee agrees promptly to notify the Company in writing upon being notified of any matter which may be subject to indemnification hereunder or upon being
served with any summons, citation, subpoena, complaint, indictment, information or other document relating to any matter which may be subject to indemnification hereunder, whether civil, criminal, arbitrative, administrative or investigative; but
the omission so to notify the Company will not relieve the Company from any liability which it may have to Indemnitee if such omission does not actually prejudice the Company’s rights and, if such omission does prejudice the Company’s
rights, it will relieve the Company from liability only to the extent of such prejudice; nor will such omission relieve the Company from any liability which it may have to Indemnitee otherwise than under this Agreement. With respect to any
Proceeding: 
 (a) The Company will be entitled to participate therein at its own expense; 
  

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 (b) Except as otherwise provided below, to the extent that it may wish, the Company
jointly with any other indemnifying party similarly notified will be entitled to assume the defense thereof, with counsel reasonably satisfactory to Indemnitee; provided, however, that the Company shall not be entitled to assume the defense
of any Proceeding if there has been a Change of Control. After notice from the Company to Indemnitee of its election so to assume the defense thereof and the assumption of such defense, the Company will not be liable to Indemnitee under this
Agreement for any Expenses subsequently incurred by Indemnitee in connection with Indemnitee’s defense except as otherwise provided below. Indemnitee shall have the right to employ his or her counsel in such Proceeding, but the fees and
expenses of such counsel incurred after notice from the Company of its assumption of the defense thereof and the assumption of such defense shall be at the expense of Indemnitee unless (i) the employment of counsel by Indemnitee has been
authorized by the Company, (ii) Indemnitee shall have reasonably concluded that there may be a conflict of interest between the Company and Indemnitee in the conduct of the defense of such action or that the Company’s counsel may not be
adequately representing Indemnitee or (iii) the Company shall not in fact have employed counsel to assume the defense of such action, in each of which cases the fees and expenses of Indemnitee’s counsel shall be at the expense of the
Company; and 
 (c) The Company shall not be liable to indemnify Indemnitee under this Agreement for any amounts paid in
settlement of any action or claim effected without the Company’s written consent. The Company shall not settle any action or claim in any manner which would impose any limitation or penalty on Indemnitee without Indemnitee’s written
consent. Neither the Company nor Indemnitee will unreasonably withhold its or his or her consent to any proposed settlement. 
 12.
Contribution. To the fullest extent permissible under applicable law, if the indemnification provided for in this Agreement is unavailable to Indemnitee for any reason whatsoever, the Company, in lieu of indemnifying Indemnitee, shall
contribute to the amount incurred by Indemnitee, whether for judgments, fines, penalties, excise taxes, amounts paid or to be paid in settlement and/or for Expenses, in connection with any claim relating to an indemnifiable event under this
Agreement, in such proportion as is deemed fair and reasonable in light of all of the circumstances of such Proceeding in order to reflect (a) the relative benefits received by the Company and Indemnitee as a result of the event(s) and/or
transaction(s) giving cause to such Proceeding; and/or (b) the relative fault of the Company (and its directors, officers, employees and agents) and Indemnitee in connection with such event(s) and/or transaction(s). 
 13. Maintenance of Insurance. The Company represents that it presently has in place certain directors’ and officers’ liability insurance
policies covering its directors and officers. Subject only to the provisions within this Section 13, the Company agrees that so long as Indemnitee shall have consented to serve or shall continue to serve as a director or officer of the Company,
or both, or as an Agent of the Company, and thereafter so long as Indemnitee shall be subject to any possible Proceeding, the Company will use all reasonable efforts to maintain in effect for the benefit of Indemnitee one or more valid, binding and
enforceable policies of 

  

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directors’ and officers’ liability insurance from established and reputable insurers, providing, in all respects, coverage both in scope and amount
which is no less favorable than that provided by such preexisting policies. Notwithstanding the foregoing, the Company shall not be required to maintain said policies of directors’ and officers’ liability insurance during any time period
if during such period such insurance is not reasonably available or if it is determined in good faith by the then directors of the Company either that: 
 (a) The premium cost of maintaining such insurance is substantially disproportionate to the amount of coverage provided thereunder; or 
 (b) The protection provided by such insurance is so limited by exclusions, deductions or otherwise that there is insufficient benefit to warrant the cost of maintaining such insurance. 
 Anything in this Agreement to the contrary notwithstanding, to the extent that and for so long as the Company shall choose to continue to maintain any
policies of directors’ and officers’ liability insurance during the period described in this Section 13, the Company shall maintain similar and equivalent insurance for the benefit of Indemnitee during such period (unless such
insurance shall be less favorable to Indemnitee than the Company’s existing policies). 
 14. Subrogation. In the event of
payment under this Agreement, the Company shall be subrogated to the extent of such payment to all of the rights of recovery of Indemnitee, who shall execute all papers required and shall do everything that may be necessary to secure such rights,
including the execution of such documents necessary to enable the Company effectively to bring suit to enforce such rights. 
 15.
Miscellaneous Provisions. 
 15.1 Severability; Partial Indemnity. If any provision or provisions of this
Agreement (or any portion thereof) shall be held by a court of competent jurisdiction to be invalid, illegal or unenforceable for any reason whatever: (a) such provision shall be limited or modified in its application to the minimum extent
necessary to avoid the invalidity, illegality or unenforceability of such provision; (b) the validity, legality and enforceability of the remaining provisions of this Agreement shall not in any way be affected or impaired thereby; and
(c) to the fullest extent possible, the provisions of this Agreement shall be construed so as to give effect to the intent manifested by the provision (or portion thereof) held invalid, illegal or unenforceable. If Indemnitee is entitled under
any provision of this Agreement to indemnification by the Company for some or a portion of any Expenses or Liabilities of any type whatsoever incurred by him or her in the investigation, defense, settlement or appeal of a Proceeding but not entitled
to all of the total amount thereof, the Company shall nevertheless indemnify Indemnitee for such total amount except as to the portion thereof for which it has been determined pursuant to Section 5 hereof that Indemnitee is not entitled.

 15.2 Identical Counterparts. This Agreement may be executed in one or more counterparts, each of which shall for all
purposes be deemed to be an 

  

 -12- 

 
original but all of which together shall constitute one and the same Agreement. Only one such counterpart signed by the party against whom enforceability is
sought needs to be produced to evidence the existence of this Agreement. 
 15.3 Interpretation of Agreement. It is
understood that the parties hereto intend this Agreement to be interpreted and enforced so as to provide indemnification to Indemnitee to the fullest extent now or hereafter permitted by law. 
 15.4 Headings. The headings of the Sections and paragraphs of this Agreement are inserted for convenience only and shall not be
deemed to constitute part of this Agreement or to affect the construction thereof. 
 15.5 Modification and Waiver. No
supplement, modification or amendment of this Agreement shall be binding unless executed in writing by both of the parties to this Agreement. No waiver of any provision of this Agreement shall be deemed to constitute a waiver of any other provision
hereof (whether or not similar), nor shall such waiver constitute a continuing waiver. No waiver of any provision of this Agreement shall be effective unless executed in writing. 
 15.6 Mutual Acknowledgement. The Company and Indemnitee acknowledge that in certain instances, federal law or applicable public
policy may prohibit the Company from indemnifying or advancing Expenses to Indemnitee under this Agreement or otherwise. 
 15.7 Notices. All notices, requests, demands and other communications hereunder shall be in writing and shall be deemed to have been duly given when (i) delivered by hand and receipted for by the party to whom said notice or
other communication shall have been directed, (ii) one business day after being deposited with a nationally recognized overnight courier service, (iii) three business days after being deposited in the U.S. Mail, certified or registered
mail, return receipt requested, or (iv) one business day after being sent by facsimile (with receipt acknowledged): 
 (a) If to Indemnitee, to the address set forth on the signature page hereof; 
 (b) If to the Company, to:

  

			
	SVB Financial Group
	 3003 Tasman Drive
 Santa Clara, California
95054-1191

	Attention:	  	President
	Facsimile:	  	(408) 496-2420

 or to such other address as may have been furnished to Indemnitee by the Company or to the Company
by Indemnitee, as the case may be. 
  

 -13- 

 15.8 Governing Law. The parties agree that this Agreement shall be governed by,
and construed and enforced in accordance with, the laws of the State of Delaware, as applied to contracts between Delaware residents entered into and to be performed entirely within Delaware. 
 15.9 Consent to Jurisdiction. The Company and Indemnitee each hereby irrevocably consent to the jurisdiction of the courts of the
State of Delaware for all purposes in connection with any action or proceeding which arises out of or relates to this Agreement and agree that any action instituted under this Agreement shall be brought only in the state courts of the State of
Delaware. 
 15.10 Entire Agreement. This Agreement represents the entire agreement between the parties hereto, and
there are no other agreements, contracts or understanding between the parties hereto with respect to the subject matter of this Agreement, except as specifically referred to herein or as provided in Sections 2 and 8 hereof. 
  

 -14- 

 IN WITNESS WHEREOF, the Company has caused this Agreement to be executed by a duly authorized officer and
Indemnitee has executed this Agreement as of the date first above written. 
  

			
	SVB FINANCIAL GROUP
		
	By:	 	  

	Name:	 	
	Title:	 	

  

			
	 [INDEMNITEE]

	
	  

	Address:    	 	[                    ]
		 	[                    ]
		 	[                    ]

  

 -15-

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