Document:

Indenture, Dated March 19, 2012

 Exhibit 4.1 
 MEDIVATION, INC., 
 Issuer 

AND 

WELLS FARGO BANK, NATIONAL ASSOCIATION, 
 Trustee 
  

 
 INDENTURE

 Dated as of March 19, 2012 

 
  

Debt Securities 

 TABLE OF CONTENTS 

 

							
			
	 	 	 	  	Page	 
	ARTICLE 1    DEFINITIONS	  	 	1	  
			
		 	Section 1.01 Definitions of Terms	  	 	1	  
		
	ARTICLE 2    ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES	  	 	5	  
			
		 	Section 2.01 Designation and Terms of Securities	  	 	5	  
			
		 	Section 2.02 Form of Securities and Trustee’s Certificate	  	 	8	  
			
		 	Section 2.03 Denominations: Provisions for Payment	  	 	8	  
			
		 	Section 2.04 Execution and Authentications	  	 	10	  
			
		 	Section 2.05 Registration of Transfer and Exchange	  	 	11	  
			
		 	Section 2.06 Temporary Securities	  	 	12	  
			
		 	Section 2.07 Mutilated, Destroyed, Lost or Stolen Securities	  	 	12	  
			
		 	Section 2.08 Cancellation	  	 	13	  
			
		 	Section 2.09 Benefits of Indenture	  	 	13	  
			
		 	Section 2.10 Authenticating Agent	  	 	14	  
			
		 	Section 2.11 Global Securities	  	 	14	  
		
	ARTICLE 3    REDEMPTION OF SECURITIES AND SINKING FUND PROVISIONS	  	 	15	  
			
		 	Section 3.01 Redemption	  	 	15	  
			
		 	Section 3.02 Notice of Redemption	  	 	15	  
			
		 	Section 3.03 Payment Upon Redemption	  	 	17	  
			
		 	Section 3.04 Sinking Fund	  	 	17	  
			
		 	Section 3.05 Satisfaction of Sinking Fund Payments with Securities	  	 	17	  
			
		 	Section 3.06 Redemption of Securities for Sinking Fund	  	 	18	  
		
	ARTICLE 4    COVENANTS	  	 	18	  
			
		 	Section 4.01 Payment of Principal, Premium and Interest	  	 	18	  
			
		 	Section 4.02 Maintenance of Office or Agency	  	 	18	  
			
		 	Section 4.03 Paying Agents	  	 	19	  
			
		 	Section 4.04 Appointment to Fill Vacancy in Office of Trustee	  	 	20	  
			
		 	Section 4.05 Compliance with Consolidation Provisions	  	 	20	  

  
 i. 

 TABLE OF CONTENTS 

 

							
		
	 	  	Page	 
	ARTICLE 5    SECURITYHOLDERS’ LISTS AND REPORTS BY THE COMPANY AND THE TRUSTEE	  	 	20	  
			
		  	Section 5.01 Company to Furnish Trustee Names and Addresses of Securityholders	  	 	20	  
			
		  	Section 5.02 Preservation Of Information; Communications With Securityholders	  	 	20	  
			
		  	Section 5.03 Reports by the Company	  	 	21	  
			
		  	Section 5.04 Reports by the Trustee	  	 	21	  
		
	ARTICLE 6    REMEDIES OF THE TRUSTEE AND SECURITYHOLDERS ON EVENT OF DEFAULT	  	 	22	  
			
		  	Section 6.01 Events of Default	  	 	22	  
			
		  	Section 6.02 Collection of Indebtedness and Suits for Enforcement by Trustee	  	 	24	  
			
		  	Section 6.03 Application of Moneys Collected	  	 	25	  
			
		  	Section 6.04 Limitation on Suits	  	 	25	  
			
		  	Section 6.05 Rights and Remedies Cumulative; Delay or Omission Not Waiver	  	 	26	  
			
		  	Section 6.06 Control by Securityholders	  	 	26	  
			
		  	Section 6.07 Undertaking to Pay Costs	  	 	27	  
		
	ARTICLE 7    CONCERNING THE TRUSTEE	  	 	27	  
			
		  	Section 7.01 Certain Duties and Responsibilities of Trustee	  	 	27	  
			
		  	Section 7.02 Certain Rights of Trustee	  	 	29	  
			
		  	Section 7.03 Trustee Not Responsible for Recitals or Issuance or Securities	  	 	31	  
			
		  	Section 7.04 May Hold Securities	  	 	31	  
			
		  	Section 7.05 Moneys Held in Trust	  	 	31	  
			
		  	Section 7.06 Compensation and Reimbursement	  	 	31	  
			
		  	Section 7.07 Reliance on Officer’s Certificate	  	 	32	  
			
		  	Section 7.08 Disqualification; Conflicting Interests	  	 	32	  
			
		  	Section 7.09 Corporate Trustee Required; Eligibility	  	 	32	  
			
		  	Section 7.10 Resignation and Removal; Appointment of Successor	  	 	33	  
			
		  	Section 7.11 Acceptance of Appointment By Successor	  	 	34	  
			
		  	Section 7.12 Merger, Conversion, Consolidation or Succession to Business	  	 	35	  
			
		  	Section 7.13 Preferential Collection of Claims Against the Company	  	 	36	  
			
		  	Section 7.14 Notice of Default	  	 	36	  

  
 ii.

 TABLE OF CONTENTS 

 

							
		
	 	  	Page	 
	ARTICLE 8    CONCERNING THE SECURITYHOLDERS	  	 	36	  
			
		 	Section 8.01 Evidence of Action by Securityholders	  	 	36	  
			
		 	Section 8.02 Proof of Execution by Securityholders	  	 	37	  
			
		 	Section 8.03 Who May be Deemed Owners	  	 	37	  
			
		 	Section 8.04 Certain Securities Owned by Company Disregarded	  	 	37	  
			
		 	Section 8.05 Actions Binding on Future Securityholders	  	 	38	  
		
	ARTICLE 9    SUPPLEMENTAL INDENTURES	  	 	38	  
			
		 	Section 9.01 Supplemental Indentures Without the Consent of Securityholders	  	 	38	  
			
		 	Section 9.02 Supplemental Indentures With Consent of Securityholders	  	 	39	  
			
		 	Section 9.03 Effect of Supplemental Indentures	  	 	40	  
			
		 	Section 9.04 Securities Affected by Supplemental Indentures	  	 	40	  
			
		 	Section 9.05 Execution of Supplemental Indentures	  	 	40	  
		
	ARTICLE 10    SUCCESSOR ENTITY	  	 	41	  
			
		 	Section 10.01 Company May Consolidate, Etc.	  	 	41	  
			
		 	Section 10.02 Successor Entity Substituted	  	 	41	  
		
	ARTICLE 11    SATISFACTION AND DISCHARGE	  	 	42	  
			
		 	Section 11.01 Satisfaction and Discharge of Indenture	  	 	42	  
			
		 	Section 11.02 Discharge of Obligations	  	 	42	  
			
		 	Section 11.03 Deposited Moneys to be Held in Trust	  	 	43	  
			
		 	Section 11.04 Payment of Moneys Held by Paying Agents	  	 	43	  
			
		 	Section 11.05 Repayment to Company	  	 	43	  
		
	ARTICLE 12    IMMUNITY OF INCORPORATORS, STOCKHOLDERS, OFFICERS AND DIRECTORS	  	 	44	  
			
		 	Section 12.01 No Recourse	  	 	44	  
		
	ARTICLE 13    MISCELLANEOUS PROVISIONS	  	 	44	  
			
		 	Section 13.01 Effect on Successors and Assigns	  	 	44	  
			
		 	Section 13.02 Actions by Successor	  	 	44	  
			
		 	Section 13.03 Surrender of Company Powers	  	 	44	  
			
		 	Section 13.04 Notices	  	 	45	  
			
		 	Section 13.05 Governing Law	  	 	45	  
			
		 	Section 13.06 Treatment of Securities as Debt	  	 	45	  

  
 iii.

 TABLE OF CONTENTS 

 

							
			
	 	 	 	  	Page	 
		 	Section 13.07 Compliance Certificates	  	 	45	  
			
		 	Section 13.08 Payments on Business Days	  	 	46	  
			
		 	Section 13.09 Conflict with Trust Indenture Act	  	 	46	  
			
		 	Section 13.10 Counterparts	  	 	46	  
			
		 	Section 13.11 Separability	  	 	46	  
			
		 	Section 13.12 Compliance Certificates	  	 	47	  
			
		 	Section 13.13 U.S.A Patriot Act	  	 	47	  
			
		 	Section 13.14 Force Majeure	  	 	47	  
			
		 	Section 13.15 Table of Contents; Headings	  	 	47	  

  

	(1)	This Table of Contents does not constitute part of the Indenture and shall not have any bearing on the interpretation of any of its terms or provisions.

  
 iv.

 INDENTURE 
 INDENTURE, dated as of March 19, 2012, among Medivation, Inc., a Delaware corporation (the “Company”), and Wells Fargo Bank, National Association, as
trustee (the “Trustee”): 
 WHEREAS, for its lawful corporate purposes, the
Company has duly authorized the execution and delivery of this Indenture to provide for the issuance of debt securities (hereinafter referred to as the “Securities”), in an unlimited aggregate principal amount to be issued from time to
time in one or more series as in this Indenture provided, as registered Securities without coupons, to be authenticated by the certificate of the Trustee; 
 WHEREAS, to provide the terms and conditions upon which the Securities are to be authenticated, issued and delivered, the Company has duly authorized the execution of
this Indenture; and 
 WHEREAS, all things necessary to make this Indenture a valid
agreement of the Company, in accordance with its terms, have been done. 
 NOW,
THEREFORE, in consideration of the premises and the purchase of the Securities by the holders thereof, it is mutually covenanted and agreed as follows for the equal and ratable benefit of the holders of Securities:

 ARTICLE 1 
 DEFINITIONS 
 Section 1.01 Definitions of Terms. 

The terms defined in this Section (except as in this Indenture or any indenture supplemental hereto otherwise expressly provided or unless
the context otherwise requires) for all purposes of this Indenture and of any indenture supplemental hereto shall have the respective meanings specified in this Section and shall include the plural as well as the singular. All other terms used in
this Indenture that are defined in the Trust Indenture Act of 1939, as amended, or that are by reference in such Act defined in the Securities Act of 1933, as amended (except as herein or any indenture supplemental hereto otherwise expressly
provided or unless the context otherwise requires), shall have the meanings assigned to such terms in said Trust Indenture Act and in said Securities Act as in force at the date of the execution of this instrument. 

“Authenticating Agent” means an authenticating agent with respect to all or any of the series of Securities
appointed by the Trustee pursuant to Section 2.10. 
 “Bankruptcy Law” means Title 11, U.S. Code,
or any similar federal or state law for the relief of debtors. 
 “Board of Directors” means the Board
of Directors (or the functional equivalent thereof) of the Company or any duly authorized committee of such Board. 

  
 1. 

 “Board Resolution” means a copy of a resolution certified by the
Secretary or an Assistant Secretary of the Company to have been duly adopted by the Board of Directors (or duly authorized committee thereof) and to be in full force and effect on the date of such certification. 

“Business Day” means, with respect to any series of Securities, any day other than a day on which federal or
state banking institutions in the Borough of Manhattan, the City of New York, or in the city of the Corporate Trust Office of the Trustee, are authorized or obligated by law, executive order or regulation to close. 

“Certificate” means a certificate signed by any Officer. The Certificate need not comply with the provisions of
Section 13.07. 
 “Commission” means the Securities and Exchange Commission, as from time to time
constituted, created under the Exchange Act, or, if at any time after the execution of this instrument such Commission is not existing and performing the duties now assigned to it under the Trust Indenture Act, then the body performing such duties
at such time. 
 “Company” means Medivation, Inc., a corporation duly organized and existing under the
laws of the State of Delaware, and, subject to the provisions of Article Ten, shall also include its successors and assigns. 

“Corporate Trust Office” means the office of the Trustee at which, at any particular time, its corporate trust
business shall be principally administered, which office at the date hereof is located at 707 Wilshire Blvd, 17th Floor, Los Angeles, California 90017, Attention: Corporate Trust Department, and shall mean for purposes of Section 4.02, c/o
Wells Fargo Bank, National Association, 625 Marquette Avenue, Minneapolis, Minnesota 55402. 

“Custodian” means any receiver, trustee, assignee, liquidator or similar official under any Bankruptcy Law.

 “Defaulted Interest” has the meaning set forth in Section 2.03. 

“Depositary” means, with respect to Securities of any series for which the Company shall determine that such
Securities will be issued as a Global Security, The Depository Trust Company, another clearing agency, or any successor registered as a clearing agency under the Exchange Act, or other applicable statute or regulation, which, in each case, shall be
designated by the Company pursuant to either Section 2.01 or 2.11. 
 “Event of Default” means,
with respect to Securities of a particular series, any event specified in Section 6.01, continued for the period of time, if any, therein designated. 
 “Exchange Act” means the United States Securities and Exchange Act of 1934, as amended, and the rules and regulations promulgated by the Commission thereunder. 

“Global Security” means a Security issued to evidence all or a part of any series of Securities which is executed
by the Company and authenticated and delivered by the Trustee to the Depositary or pursuant to the Depositary’s instruction, all in accordance with the Indenture, which shall be registered in the name of the Depositary or its nominee.

  
 2. 

 “Governmental Obligations” means securities that are (a) direct
obligations of the United States of America for the payment of which its full faith and credit is pledged or (b) obligations of a Person controlled or supervised by and acting as an agency or instrumentality of the United States of America, the
payment of which is unconditionally guaranteed as a full faith and credit obligation by the United States of America that, in either case, are not callable or redeemable at the option of the issuer thereof at any time prior to the stated maturity of
the Securities, and shall also include a depositary receipt issued by a bank or trust company as custodian with respect to any such Governmental Obligation or a specific payment of principal of or interest on any such Governmental Obligation held by
such custodian for the account of the holder of such depositary receipt; provided, however, that (except as required by law) such custodian is not authorized to make any deduction from the amount payable to the holder of such depositary receipt from
any amount received by the custodian in respect of the Governmental Obligation or the specific payment of principal of or interest on the Governmental Obligation evidenced by such depositary receipt. 

“herein”, “hereof” and “hereunder”, and other words of
similar import, refer to this Indenture as a whole and not to any particular Article, Section or other subdivision. 

“Indenture” means this instrument as originally executed or as it may from time to time be supplemented or
amended by one or more indentures supplemental hereto entered into in accordance with the terms hereof and shall include the terms of particular series of Securities established as contemplated by Section 2.01. 

“Interest Payment Date”, when used with respect to any installment of interest on a Security of a particular
series, means the date specified in such Security or in a Board Resolution or in an indenture supplemental hereto with respect to such series as the fixed date on which an installment of interest with respect to Securities of that series is due and
payable. 
 “Officer” means, with respect to the Company, the chairman of the Board of Directors, the
chief executive officer, the president, the chief financial officer, the chief operating officer, any executive vice president, any senior vice president, any vice president, the treasurer or any assistant treasurer, the controller or any assistant
controller or the secretary or any assistant secretary. 
 “Officer’s Certificate” means a
certificate signed by any Officer. Each such certificate shall include the statements provided for in Section 13.07(b), if and to the extent required by the provisions thereof. 

“Opinion of Counsel” means an opinion in writing subject to customary exceptions of legal counsel, who may be an
employee of or counsel for the Company, that is delivered to the Trustee in accordance with the terms hereof. Each such opinion shall include the statements provided for in Section 13.07(b), if and to the extent required by the provisions
thereof. 

  
 3. 

 “Outstanding”, when used with reference to Securities of any series,
means, subject to the provisions of Section 8.04, as of any particular time, all Securities of that series theretofore authenticated and delivered by the Trustee under this Indenture, except (a) Securities theretofore canceled by the
Trustee or any paying agent, or delivered to the Trustee or any paying agent for cancellation or that have previously been canceled; (b) Securities or portions thereof for the payment or redemption of which moneys or Governmental Obligations in
the necessary amount shall have been deposited in trust with the Trustee or with any paying agent (other than the Company) or shall have been set aside and segregated in trust by the Company (if the Company shall act as its own paying agent);
provided, however, that if such Securities or portions of such Securities are to be redeemed prior to the maturity thereof, notice of such redemption shall have been given as provided in Article Three, or provision satisfactory to the Trustee shall
have been made for giving such notice; and (c) Securities in lieu of or in substitution for which other Securities shall have been authenticated and delivered pursuant to the terms of Section 2.07. 

“Person” means any individual, corporation, partnership, joint venture, joint-stock company, limited liability
company, association, trust, unincorporated organization, any other entity or organization, including a government or political subdivision or an agency or instrumentality thereof. 

“Predecessor Security” of any particular Security means every previous Security evidencing all or a portion of
the same debt as that evidenced by such particular Security; and, for the purposes of this definition, any Security authenticated and delivered under Section 2.07 in lieu of a lost, destroyed or stolen Security shall be deemed to evidence the
same debt as the lost, destroyed or stolen Security. 
 “Responsible Officer” when used with respect to
the Trustee means any officer of the Trustee assigned by the Trustee to administer its corporate trust matters with respect to this Indenture (which, for the avoidance of doubt, includes without limitation any supplemental indenture hereto).

 “Securities” has the meaning stated in the first recital of this Indenture and more particularly
means any Securities authenticated and delivered under this Indenture. 
 “Securities Act” means the
Securities Act of 1933, as amended. 
 “Securityholder”, “holder of Securities”,
“registered holder”, or other similar term, means the Person or Persons in whose name or names a particular Security is registered on the Security Register kept for that purpose in accordance with the terms of this Indenture.

 “Security Register” and “Security Registrar” shall have the meanings as set
forth in Section 2.05. 
 “Subsidiary” means, with respect to any Person: 

(1) any corporation or company a majority of whose capital stock with voting power, under ordinary circumstances, to
elect directors is, at the date of determination, directly or indirectly, owned by such Person (a “subsidiary”), by one or more subsidiaries of such Person or by such Person and one or more subsidiaries of such Person;

  
 4. 

 (2) a partnership in which such Person or a subsidiary of such Person
is, at the date of determination, a general partner of such partnership; or 
 (3) any partnership, limited
liability company or other Person in which such Person, a subsidiary of such Person or such Person and one or more subsidiaries of such Person, directly or indirectly, at the date of determination, have (x) at least a majority ownership
interest or (y) the power to elect or appoint or direct the election or appointment of the managing partner or member of such Person or, if applicable, a majority of the directors or other governing body of such Person. 

“Trustee” means Wells Fargo Bank, National Association, and, subject to the provisions of Article Seven, shall
also include its successors and assigns, and, if at any time there is more than one Person acting in such capacity hereunder, “Trustee” shall mean each such Person. The term “Trustee” as used with respect to a particular series
of the Securities shall mean the trustee with respect to that series. 
 “Trust Indenture Act” means the
Trust Indenture Act of 1939, as amended. 
 “U.S.A. Patriot Act” means the Uniting and Strengthening
America by Providing Appropriate Tools Required to Intercept and Obstruct Terrorism Act of 2001, Pub. L. 107-56, as amended and signed into law October 26, 2001. 
 ARTICLE 2 
 ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND
EXCHANGE OF SECURITIES 
 Section 2.01 Designation and Terms of Securities. 

(a) The aggregate principal amount of Securities that may be authenticated and delivered under this Indenture is unlimited. The
Securities may be issued in one or more series up to the aggregate principal amount of Securities of that series from time to time authorized by or pursuant to a Board Resolution or pursuant to one or more indentures supplemental hereto. Prior to
the initial issuance of Securities of any series, there shall be established in or pursuant to a Board Resolution, and set forth in an Officer’s Certificate, or established in one or more indentures supplemental hereto: 

(1) the title of the Securities of the series (which shall distinguish the Securities of that series from all other Securities);

 (2) any limit upon the aggregate principal amount of the Securities of that series that may be authenticated and
delivered under this Indenture (except for Securities authenticated and delivered upon registration of transfer of, or in exchange for, or in lieu of, other Securities of that series); 

  
 5. 

 (3) the maturity date or dates on which the principal of the Securities of the
series is payable; 
 (4) the form of the Securities of the series including the form of the certificate of
authentication for such series; 
 (5) the applicability of any guarantees; 

(6) whether or not the Securities will be secured or unsecured, and the terms of any secured debt; 

(7) whether the Securities rank as senior debt, senior subordinated debt, subordinated debt or any combination thereof, and the
terms of any subordination; 
 (8) if the price (expressed as a percentage of the aggregate principal amount thereof) at
which such Securities will be issued is a price other than the principal amount thereof, the portion of the principal amount thereof payable upon declaration of acceleration of the maturity thereof, or if applicable, the portion of the principal
amount of such Securities that is convertible into another security or the method by which any such portion shall be determined; 
 (9) the interest rate or rates, which may be fixed or variable, or the method for determining the rate and the date interest will begin to accrue, the dates interest will be payable and the regular
record dates for interest payment dates or the method for determining such dates; 
 (10) the Company’s right, if
any, to defer the payment of interest and the maximum length of any such deferral period; 
 (11) if applicable, the
date or dates after which, or the period or periods during which, and the price or prices at which, the Company may at its option, redeem the series of Securities pursuant to any optional or provisional redemption provisions and the terms of those
redemption provisions; 
 (12) the date or dates, if any, on which, and the price or prices at which the Company is
obligated, pursuant to any mandatory sinking fund or analogous fund provisions or otherwise, to redeem, or at the Securityholder’s option to purchase, the series of Securities and the currency or currency unit in which the Securities are
payable; 
 (13) the denominations in which the Securities of the series shall be issuable, if other than denominations
of one thousand U.S. dollars ($1,000) or any integral multiple thereof; 
 (14) any and all other terms (including
terms, to the extent applicable, relating to any auction or remarketing of the Securities of that series and any security for the obligations of the Company with respect to such Securities) with respect to such series (which terms shall not be
inconsistent with the terms of this Indenture, as amended by any supplemental indenture) including any terms which may be required by or advisable under United States laws or regulations or advisable in connection with the marketing of Securities of
that series; 

  
 6. 

 (15) whether the Securities of the series shall be issued in whole or in part in the
form of a Global Security or Securities; the terms and conditions, if any, upon which such Global Security or Securities may be exchanged in whole or in part for other individual Securities; and the Depositary for such Global Security or Securities;

 (16) if applicable, the provisions relating to conversion or exchange of any Securities of the series and the terms
and conditions upon which such Securities will be so convertible or exchangeable, including the conversion or exchange price, as applicable, or how it will be calculated and may be adjusted, any mandatory or optional (at the Company’s option or
the holders’ option) conversion or exchange features, the applicable conversion or exchange period and the manner of settlement for any conversion or exchange, which may, without limitation, include the payment of cash as well as the delivery
of securities; 
 (17) if other than the full principal amount thereof, the portion of the principal amount of
Securities of the series which shall be payable upon declaration of acceleration of the maturity thereof pursuant to Section 6.01; 
 (18) any changes in or additions to the covenants applicable to the series of Securities being issued, including, among others, the consolidation, merger or sale covenant; 

(19) only additions to or changes in the Events of Default with respect to the Securities and any change in the right of the
Trustee or the Securityholders to declare the principal, premium, if any, and interest, if any, with respect to such Securities to be due and payable; 
 (20) only additions to or changes in or deletions of the provisions relating to covenant defeasance and legal defeasance; 
 (21) only additions to or changes in the provisions relating to satisfaction and discharge of this Indenture; 
 (22) only additions to or changes in the provisions relating to the modification of this Indenture both with and without the consent of Securityholders of Securities issued under this Indenture;

 (23) the currency of payment of Securities if other than U.S. dollars and the manner of determining the equivalent
amount in U.S. dollars; 
 (24) if interest will be payable in cash or additional Securities at the Company’s or
the Securityholders’ option, the terms and conditions upon which the election may be made; 
 (25) the terms and
conditions, if any, upon which the Company shall pay amounts in addition to the stated interest, premium, if any and principal amounts of the Securities of the series to any Securityholder that is not a “United States person” for federal
tax purposes; 

  
 7. 

 (26) any restrictions on transfer, sale or assignment of the Securities of the
series; and 
 (27) any other specific terms, preferences, rights or limitations of, or restrictions on, the Securities,
any other additions or changes in the provisions of this Indenture, and any terms that may be required by us or advisable under applicable laws or regulations. 
 (b) All Securities of any one series shall be substantially identical except as may otherwise be provided in or pursuant to any such Board Resolution or in any indentures supplemental hereto.

 If any of the terms of the series are established by action taken pursuant to a Board Resolution of the Company, a copy of an
appropriate record of such action shall be certified by the secretary or an assistant secretary of the Company and delivered to the Trustee at or prior to the delivery of the Officer’s Certificate of the Company setting forth the terms of the
series. 
 Securities of any particular series may be issued at various times, with different dates on which the principal or
any installment of principal is payable, with different rates of interest, if any, or different methods by which rates of interest may be determined, with different dates on which such interest may be payable and with different redemption dates.

 Section 2.02 Form of Securities and Trustee’s Certificate. 

The Securities of any series and the Trustee’s certificate of authentication to be borne by such Securities shall be substantially of
the tenor and purport as set forth in one or more indentures supplemental hereto or as provided in a Board Resolution, and set forth in an Officer’s Certificate, and they may have such letters, numbers or other marks of identification or
designation and such legends or endorsements printed, lithographed or engraved thereon as the Company may deem appropriate and as are not inconsistent with the provisions of this Indenture, or as may be required to comply with any law or with any
rule or regulation made pursuant thereto or with any rule or regulation of any securities exchange on which Securities of that series may be listed, or to conform to usage. 
 Section 2.03 Denominations: Provisions for Payment. 
 The Securities
shall be issuable as registered Securities and in the denominations of one thousand U.S. dollars ($1,000) or any integral multiple thereof, subject to Section 2.01(a)(13). The Securities of a particular series shall bear interest payable on the
dates and at the rate specified with respect to that series. Subject to Section 2.01(a)(23), the principal of and the interest on the Securities of any series, as well as any premium thereon in the case of a redemption or repurchase thereof
prior to maturity, and any cash amount due upon the conversion or exchange thereof, shall be payable in the coin or currency of the United States of America that at the time is legal tender for public and private debt, at the office or agency of the
Company in the continental United States of America maintained for that purpose. Each Security shall be dated the date of its authentication. Interest on the Securities shall be computed on the basis of a 360-day year composed of twelve 30-day
months. 

  
 8. 

 The interest installment on any Security that is payable, and is punctually paid or duly
provided for, on any Interest Payment Date for Securities of that series shall be paid to the Person in whose name said Security (or one or more Predecessor Securities) is registered at the close of business on the regular record date for such
interest installment. In the event that any Security of a particular series or portion thereof is called for redemption and the redemption date is subsequent to a regular record date with respect to any Interest Payment Date and prior to such
Interest Payment Date, interest on such Security will be paid upon presentation and surrender of such Security as provided in Section 3.03. 
 Any interest on any Security that is payable, but is not punctually paid or duly provided for, on any Interest Payment Date for Securities of the same series (herein called “Defaulted Interest”)
shall forthwith cease to be payable to the registered holder on the relevant regular record date by virtue of having been such holder; and such Defaulted Interest shall be paid by the Company, at its election, as provided in clause (1) or
clause (2) below: 
 (1) The Company may make payment of any Defaulted Interest on Securities to the Persons in
whose names such Securities (or their respective Predecessor Securities) are registered at the close of business on a special record date for the payment of such Defaulted Interest, which shall be fixed in the following manner: the Company shall
notify the Trustee in writing of the amount of Defaulted Interest proposed to be paid on each such Security and the date of the proposed payment, and at the same time the Company shall deposit with the Trustee an amount of money equal to the
aggregate amount proposed to be paid in respect of such Defaulted Interest or shall make arrangements satisfactory to the Trustee for such deposit prior to the date of the proposed payment, such money when deposited to be held in trust for the
benefit of the Persons entitled to such Defaulted Interest as in this clause provided. Thereupon the Trustee shall fix a special record date for the payment of such Defaulted Interest which shall not be more than 15 nor less than 10 days prior to
the date of the proposed payment and not less than 10 days after the receipt by the Trustee of the notice of the proposed payment. The Trustee shall promptly notify the Company of such special record date and, in the name and at the expense of the
Company, shall cause notice of the proposed payment of such Defaulted Interest and the special record date therefor to be mailed, first class postage prepaid, to each Securityholder at his or her address as it appears in the Security Register (as
hereinafter defined), not less than 10 days prior to such special record date. Notice of the proposed payment of such Defaulted Interest and the special record date therefor having been mailed as aforesaid, such Defaulted Interest shall be paid to
the Persons in whose names such Securities (or their respective Predecessor Securities) are registered on such special record date. 
 (2) The Company may make payment of any Defaulted Interest on any Securities in any other lawful manner not inconsistent with the requirements of any securities exchange on which such Securities
may be listed, and upon such notice as may be required by such exchange, if, after notice given by the Company to the Trustee of the proposed payment pursuant to this clause, such manner of payment shall be deemed practicable by the Trustee.

  
 9. 

 Unless otherwise set forth in a Board Resolution or one or more indentures supplemental
hereto establishing the terms of any series of Securities pursuant to Section 2.01 hereof, the term “regular record date” as used in this Section with respect to a series of Securities and any Interest Payment Date for such series
shall mean either the fifteenth day of the month immediately preceding the month in which an Interest Payment Date established for such series pursuant to Section 2.01 hereof shall occur, if such Interest Payment Date is the first day of a
month, or the first day of the month in which an Interest Payment Date established for such series pursuant to Section 2.01 hereof shall occur, if such Interest Payment Date is the fifteenth day of a month, whether or not such date is a
Business Day. 
 Subject to the foregoing provisions of this Section, each Security of a series delivered under this Indenture
upon transfer of or in exchange for or in lieu of any other Security of such series shall carry the rights to interest accrued and unpaid, and to accrue, that were carried by such other Security. 

Section 2.04 Execution and Authentications. 
 The Securities shall be signed on behalf of the Company by one of its Officers. Signatures may be in the form of a manual or facsimile signature. 

The Company may use the facsimile signature of any Person who shall have been an Officer (at the time of execution), notwithstanding the
fact that at the time the Securities shall be authenticated and delivered or disposed of such Person shall have ceased to be such an officer of the Company. The Securities may contain such notations, legends or endorsements required by law, stock
exchange rule or usage. Each Security shall be dated the date of its authentication by the Trustee. 
 A Security shall not be
valid until authenticated manually by an authorized signatory of the Trustee, or by an Authenticating Agent. Such signature shall be conclusive evidence that the Security so authenticated has been duly authenticated and delivered hereunder and that
the holder is entitled to the benefits of this Indenture. At any time and from time to time after the execution and delivery of this Indenture, the Company may deliver Securities of any series executed by the Company to the Trustee for
authentication, together with a written order of the Company for the authentication and delivery of such Securities, signed by an Officer, and the Trustee in accordance with such written order shall authenticate and deliver such Securities.

 Upon the Company’s delivery of any such authentication order to the Trustee at any time after the initial issuance of
Securities under this Indenture, the Trustee shall be provided with, and (subject to Sections 315(a) through 315(d) of the Trust Indenture Act) shall be fully protected in relying upon, (1) an Opinion of Counsel or reliance letter and
(2) an Officer’s Certificate stating that all conditions precedent to the execution, authentication and delivery of such Securities are in conformity with the provisions of this Indenture. 

The Trustee shall not be required to authenticate such Securities if the issue of such Securities pursuant to this Indenture will affect
the Trustee’s own rights, duties or immunities under the Securities and this Indenture or otherwise in a manner that is not reasonably acceptable to the Trustee. 

  
 10.

 Section 2.05 Registration of Transfer and Exchange. 

(a) Securities of any series may be exchanged upon presentation thereof at the office or agency of the Company in the continental
United States of America designated for such purpose, for other Securities of such series of authorized denominations, and for a like aggregate principal amount, upon payment of a sum sufficient to cover any tax or other governmental charge in
relation thereto, all as provided in this Section. In respect of any Securities so surrendered for exchange, the Company shall execute, the Trustee shall authenticate and such office or agency shall deliver in exchange therefor the Security or
Securities of the same series that the Securityholder making the exchange shall be entitled to receive, bearing numbers not contemporaneously outstanding. 
 (b) The Company shall keep, or cause to be kept at its office or agency in the continental United States of America designated for such purpose a register or registers (herein referred to as the
“Security Register”) in which, subject to such reasonable regulations as it may prescribe, the Company shall register the Securities and the transfers of Securities as in this Article provided and which at all reasonable times shall be
open for inspection by the Trustee. The registrar for the purpose of registering Securities and transfer of Securities as herein provided shall be appointed as authorized by Board Resolution (the “Security Registrar”). 

Upon surrender for transfer of any Security at the office or agency of the Company designated for such purpose, the Company shall
execute, the Trustee shall authenticate and such office or agency shall deliver in the name of the transferee or transferees a new Security or Securities of the same series as the Security presented for a like aggregate principal amount. 

All Securities presented or surrendered for exchange or registration of transfer, as provided in this Section, shall be accompanied (if
so required by the Company or the Security Registrar) by a written instrument or instruments of transfer, in form satisfactory to the Company or the Security Registrar, duly executed by the registered holder or by such holder’s duly authorized
attorney in writing. 
 (c) Except as provided pursuant to Section 2.01 pursuant to a Board Resolution, and set
forth in an Officer’s Certificate, or established in one or more indentures supplemental to this Indenture, no service charge shall be made for any exchange or registration of transfer of Securities, or issue of new Securities in case of
partial redemption of any series or repurchase, conversion or exchange of less than the entire principal amount of a Security, but the Company may require payment of a sum sufficient to cover any tax or other governmental charge in relation thereto,
other than exchanges pursuant to Section 2.06, Section 3.03(b) and Section 9.04 not involving any transfer. 

(d) The Company shall not be required (i) to issue, exchange or register the transfer of any Securities during a period
beginning at the opening of business 15 days before the day of the mailing of a notice of redemption of less than all the Outstanding Securities of the same series and ending at the close of business on the day of such mailing, nor (ii) to
register the transfer of or exchange any Securities of any series or portions thereof called for redemption or surrendered for repurchase, but not validly withdrawn, other than the unredeemed portion of any such Securities being redeemed in part or
not surrendered for repurchase, as the case may be. The provisions of this Section 2.05 are, with respect to any Global Security, subject to Section 2.11 hereof. 

  
 11.

 The Trustee shall have no obligation or duty to monitor, determine or inquire as to
compliance with any restrictions on transfer imposed under this Indenture or under applicable law with respect to any transfer of any interest in any Security (including any transfers between or among depositary participants or beneficial owners of
interests in any Global Security) other than to require delivery of such certificates and other documentation or evidence as are expressly required by, and to do so if and when expressly required by the terms of, this Indenture, and to examine the
same to determine substantial compliance as to form with the express requirements hereof. 
 Section 2.06 Temporary
Securities. 
 Pending the preparation of definitive Securities of any series, the Company may execute, and the Trustee shall
authenticate and deliver, temporary Securities (printed, lithographed or typewritten) of any authorized denomination. Such temporary Securities shall be substantially in the form of the definitive Securities in lieu of which they are issued, but
with such omissions, insertions and variations as may be appropriate for temporary Securities, all as may be determined by the Company. Every temporary Security of any series shall be executed by the Company and be authenticated by the Trustee upon
the same conditions and in substantially the same manner, and with like effect, as the definitive Securities of such series. Without unnecessary delay the Company will execute and will furnish definitive Securities of such series and thereupon any
or all temporary Securities of such series may be surrendered in exchange therefor (without charge to the holders), at the office or agency of the Company in the continental United States of America designated for the purpose, and the Trustee shall
authenticate and such office or agency shall deliver in exchange for such temporary Securities an equal aggregate principal amount of definitive Securities of such series, unless the Company advises the Trustee to the effect that definitive
Securities need not be executed and furnished until further notice from the Company. Until so exchanged, the temporary Securities of such series shall be entitled to the same benefits under this Indenture as definitive Securities of such series
authenticated and delivered hereunder. 
 Section 2.07 Mutilated, Destroyed, Lost or Stolen Securities. 

In case any temporary or definitive Security shall become mutilated or be destroyed, lost or stolen, the Company (subject to the next
succeeding sentence) shall execute, and upon the Company’s request the Trustee (subject as aforesaid) shall authenticate and deliver, a new Security of the same series, bearing a number not contemporaneously outstanding, in exchange and
substitution for the mutilated Security, or in lieu of and in substitution for the Security so destroyed, lost or stolen. In every case the applicant for a substituted Security shall furnish to the Company and the Trustee such security or indemnity
as may be required by them to save each of them harmless, and, in every case of destruction, loss or theft, the applicant shall also furnish to the Company and the Trustee evidence to their satisfaction of the destruction, loss or theft of the
applicant’s Security and of the ownership thereof. The Trustee may authenticate any such substituted Security and deliver the same upon the written request or authorization of any officer of the Company. Upon the issuance of any substituted
Security, the Company may require the payment of a sum sufficient to cover any tax or other governmental charge that may be imposed in relation thereto and any other expenses (including the fees and expenses of the Trustee) connected therewith.

  
 12.

 In case any Security that has matured or is about to mature shall become mutilated or be
destroyed, lost or stolen, the Company may, instead of issuing a substitute Security, pay or authorize the payment of the same (without surrender thereof except in the case of a mutilated Security) if the applicant for such payment shall furnish to
the Company and the Trustee such security or indemnity as they may require to save them harmless, and, in case of destruction, loss or theft, evidence to the satisfaction of the Company and the Trustee of the destruction, loss or theft of such
Security and of the ownership thereof. 
 Every replacement Security issued pursuant to the provisions of this Section shall
constitute an additional contractual obligation of the Company whether or not the mutilated, destroyed, lost or stolen Security shall be found at any time, or be enforceable by anyone, and shall be entitled to all the benefits of this Indenture
equally and proportionately with any and all other Securities of the same series duly issued hereunder. All Securities shall be held and owned upon the express condition that the foregoing provisions are exclusive with respect to the replacement or
payment of mutilated, destroyed, lost or stolen Securities, and shall preclude (to the extent lawful) any and all other rights or remedies, notwithstanding any law or statute existing or hereafter enacted to the contrary with respect to the
replacement or payment of negotiable instruments or other securities without their surrender. 
 Section 2.08
Cancellation. 
 All Securities surrendered for the purpose of payment, redemption, repurchase, exchange, registration of
transfer or conversion or exchange shall, if surrendered to the Company or any paying agent (or any other applicable agent), be delivered to the Trustee for cancellation, or, if surrendered to the Trustee, shall be cancelled by it, and no Securities
shall be issued in lieu thereof except as expressly required or permitted by any of the provisions of this Indenture. On request of the Company at the time of such surrender, the Trustee shall deliver to the Company canceled Securities held by the
Trustee. In the absence of such request the Trustee may dispose of canceled Securities in accordance with its standard procedures and deliver a certificate of disposition to the Company. If the Company shall otherwise acquire any of the Securities,
however, such acquisition shall not operate as a redemption or satisfaction of the indebtedness represented by such Securities unless and until the same are delivered to the Trustee for cancellation. 

Section 2.09 Benefits of Indenture. 
 Nothing in this Indenture or in the Securities, express or implied, shall give or be construed to give to any Person, other than the parties hereto and the holders of the Securities, any legal or
equitable right, remedy or claim under or in respect of this Indenture, or under any covenant, condition or provision herein contained; all such covenants, conditions and provisions being for the sole benefit of the parties hereto and of the holders
of the Securities. 

  
 13.

 Section 2.10 Authenticating Agent. 

So long as any of the Securities of any series remain Outstanding there may be an Authenticating Agent for any or all such series of
Securities which the Trustee shall have the right to appoint. Said Authenticating Agent shall be authorized to act on behalf of the Trustee to authenticate Securities of such series issued upon exchange, transfer or partial redemption, repurchase or
conversion thereof, and Securities so authenticated shall be entitled to the benefits of this Indenture and shall be valid and obligatory for all purposes as if authenticated by the Trustee hereunder. All references in this Indenture to the
authentication of Securities by the Trustee shall be deemed to include authentication by an Authenticating Agent for such series. Each Authenticating Agent shall be acceptable to the Company and shall be a corporation that has a combined capital and
surplus, as most recently reported or determined by it, sufficient under the laws of any jurisdiction under which it is organized or in which it is doing business to conduct a trust business, and that is otherwise authorized under such laws to
conduct such business and is subject to supervision or examination by federal or state authorities. If at any time any Authenticating Agent shall cease to be eligible in accordance with these provisions, it shall resign immediately. 

Any Authenticating Agent may at any time resign by giving written notice of resignation to the Trustee and to the Company. The Trustee
may at any time (and upon request by the Company shall) terminate the agency of any Authenticating Agent by giving written notice of termination to such Authenticating Agent and to the Company. Upon resignation, termination or cessation of
eligibility of any Authenticating Agent, the Trustee may appoint an eligible successor Authenticating Agent acceptable to the Company. Any successor Authenticating Agent, upon acceptance of its appointment hereunder, shall become vested with all the
rights, powers and duties of its predecessor hereunder as if originally named as an Authenticating Agent pursuant hereto. 

Section 2.11 Global Securities. 
 (a) If the Company shall establish pursuant to Section 2.01 that the Securities of a particular series are to be issued as a Global Security, then the Company shall execute and the Trustee
shall, in accordance with Section 2.04, authenticate and deliver, a Global Security that (i) shall represent, and shall be denominated in an amount equal to the aggregate principal amount of, all of the Outstanding Securities of such
series, (ii) shall be registered in the name of the Depositary or its nominee, (iii) shall be delivered by the Trustee to the Depositary or pursuant to the Depositary’s instruction (or if the Depositary names the Trustee as its
custodian, retained by the Trustee) and (iv) shall bear a legend substantially to the following effect: “Except as otherwise provided in Section 2.11 of the Indenture, this Security may be transferred, in whole but not in part, only
to another nominee of the Depositary or to a successor Depositary or to a nominee of such successor Depositary.” 
 (b)
Notwithstanding the provisions of Section 2.05, the Global Security of a series may be transferred, in whole but not in part and in the manner provided in Section 2.05, only to another nominee of the Depositary for such series, or to a
successor Depositary for such series selected or approved by the Company or to a nominee of such successor Depositary. 

  
 14.

 (c) If at any time the Depositary for a series of the Securities notifies the Company
that it is unwilling or unable to continue as Depositary for such series or if at any time the Depositary for such series shall no longer be registered or in good standing under the Exchange Act, or other applicable statute or regulation, and a
successor Depositary for such series is not appointed by the Company within 90 days after the Company receives such notice or becomes aware of such condition, as the case may be, or if an Event of Default has occurred and is continuing and the
Company has received a request from the Depositary or from the Trustee, this Section 2.11 shall no longer be applicable to the Securities of such series and the Company will execute, and subject to Section 2.04, the Trustee will
authenticate and deliver the Securities of such series in definitive registered form without coupons, in authorized denominations, and in an aggregate principal amount equal to the principal amount of the Global Security of such series in exchange
for such Global Security. In addition, the Company may at any time determine that the Securities of any series shall no longer be represented by a Global Security and that the provisions of this Section 2.11 shall no longer apply to the
Securities of such series. In such event the Company will execute and, subject to Section 2.04, the Trustee, upon receipt of an Officer’s Certificate evidencing such determination by the Company, will authenticate and deliver the
Securities of such series in definitive registered form without coupons, in authorized denominations, and in an aggregate principal amount equal to the principal amount of the Global Security of such series in exchange for such Global Security. Upon
the exchange of the Global Security for such Securities in definitive registered form without coupons, in authorized denominations, the Global Security shall be canceled by the Trustee. Such Securities in definitive registered form issued in
exchange for the Global Security pursuant to this Section 2.11(c) shall be registered in such names and in such authorized denominations as the Depositary, pursuant to instructions from its direct or indirect participants or otherwise, shall
instruct the Trustee. The Trustee shall deliver such Securities to the Depositary for delivery to the Persons in whose names such Securities are so registered. 
 ARTICLE 3 
 REDEMPTION OF SECURITIES AND SINKING FUND PROVISIONS

 Section 3.01 Redemption. 
 The Company may redeem the Securities of any series issued hereunder on and after the dates and in accordance with the terms established for such series pursuant to Section 2.01 hereof. 

Section 3.02 Notice of Redemption. 
 (a) In case the Company shall desire to exercise such right to redeem all or, as the case may be, a portion of the Securities of any series in accordance with any right the Company reserved for
itself to do so pursuant to Section 2.01 hereof, the Company shall, or shall cause the Trustee to, give notice of such redemption to holders of the Securities of such series to be redeemed by mailing, first class postage prepaid (or with regard
to any Global Security held in book entry form, by electronic mail), a notice of such redemption not less than 30 days and not more than 60 days before the date fixed for redemption of that series to such holders at their last addresses as they
shall appear upon the Security Register, unless a shorter period is specified in 

  
 15.

 
the Securities to be redeemed; provided, that if the Company intends to cause the Trustee to give such notice, the Company delivers to the Trustee, at least 5 days (unless a shorter time should
be acceptable to the Trustee) prior to the notice date, an Officer’s Certificate requesting that the Trustee give such notice and setting forth the information to be stated in such notice. Any notice that is mailed in the manner herein provided
shall be conclusively presumed to have been duly given, whether or not the registered holder receives the notice. In any case, failure duly to give such notice to the holder of any Security of any series designated for redemption in whole or in
part, or any defect in the notice, shall not affect the validity of the proceedings for the redemption of any other Securities of such series or any other series. In the case of any redemption of Securities prior to the expiration of any restriction
on such redemption provided in the terms of such Securities or elsewhere in this Indenture, the Company shall furnish the Trustee with an Officer’s Certificate evidencing compliance with any such restriction. 

Each such notice of redemption shall specify the date fixed for redemption and the redemption price at which Securities of that series
are to be redeemed, and shall state that payment of the redemption price of such Securities to be redeemed will be made at the office or agency of the Company in the continental United States of America, upon presentation and surrender of such
Securities, that interest accrued to the date fixed for redemption will be paid as specified in said notice, that from and after said date interest will cease to accrue and that the redemption is from a sinking fund, if such is the case. If less
than all the Securities of a series are to be redeemed, the notice to the holders of Securities of that series to be redeemed in part shall specify the particular Securities to be so redeemed. 

In case any Security is to be redeemed in part only, the notice that relates to such Security shall state the portion of the principal
amount thereof to be redeemed, and shall state that on and after the redemption date, upon surrender of such Security, a new Security or Securities of such series in principal amount equal to the unredeemed portion thereof will be issued.

 (b) The Company shall give the Trustee at least 45 days’ notice (unless a shorter notice shall be satisfactory to
the Trustee) in advance of the date fixed for redemption as to the aggregate principal amount of Securities of the series to be redeemed, and thereupon the Trustee shall select, by lot or in such other manner as it shall deem appropriate and fair in
its discretion and that may provide for the selection of a portion or portions (equal to one thousand U.S. dollars ($1,000) or any integral multiple thereof) of the principal amount of such Securities of a denomination larger than $1,000, the
Securities to be redeemed and shall thereafter promptly notify the Company in writing of the numbers of the Securities to be redeemed, in whole or in part. The Company may, if and whenever it shall so elect, by delivery of instructions signed on its
behalf by an Officer, instruct the Trustee or any paying agent to call all or any part of the Securities of a particular series for redemption and to give notice of redemption in the manner set forth in this Section, such notice to be in the name of
the Company or its own name as the Trustee or such paying agent may deem advisable. In any case in which notice of redemption is to be given by the Trustee or any such paying agent, the Company shall deliver or cause to be delivered to, or permit to
remain with, the Trustee or such paying agent, as the case may be, such Security Register, transfer books or other records, or suitable copies or extracts therefrom, sufficient to enable the Trustee or such paying agent to give any notice by mail
that may be required under the provisions of this Section. 

  
 16.

 Section 3.03 Payment Upon Redemption. 

(a) If the giving of notice of redemption shall have been completed as above provided, the Securities or portions of Securities of
the series to be redeemed specified in such notice shall become due and payable on the date and at the place stated in such notice at the applicable redemption price, together with interest accrued to the date fixed for redemption and interest on
such Securities or portions of Securities shall cease to accrue on and after the date fixed for redemption, unless the Company shall default in the payment of such redemption price and accrued interest with respect to any such Security or portion
thereof. On presentation and surrender of such Securities on or after the date fixed for redemption at the place of payment specified in the notice, said Securities shall be paid and redeemed at the applicable redemption price for such series,
together with interest accrued thereon to the date fixed for redemption (but if the date fixed for redemption is an Interest Payment Date, the interest installment payable on such date shall be payable to the registered holder at the close of
business on the applicable record date pursuant to Section 2.03). 
 (b) Upon presentation of any Security of such
series that is to be redeemed in part only, the Company shall execute and the Trustee shall authenticate and the office or agency where the Security is presented shall deliver to the holder thereof, at the expense of the Company, a new Security of
the same series of authorized denominations in principal amount equal to the unredeemed portion of the Security so presented. 

Section 3.04 Sinking Fund. 
 The provisions of Sections 3.04, 3.05 and 3.06 shall be applicable to any sinking fund for the retirement of Securities of a series, except as otherwise specified as contemplated by Section 2.01 for
Securities of such series. 
 The minimum amount of any sinking fund payment provided for by the terms of Securities of any
series is herein referred to as a “mandatory sinking fund payment,” and any payment in excess of such minimum amount provided for by the terms of Securities of any series is herein referred to as an “optional sinking fund
payment”. If provided for by the terms of Securities of any series, the cash amount of any sinking fund payment may be subject to reduction as provided in Section 3.05. Each sinking fund payment shall be applied to the redemption of
Securities of any series as provided for by the terms of Securities of such series. 
 Section 3.05 Satisfaction of
Sinking Fund Payments with Securities. 
 The Company (i) may deliver Outstanding Securities of a series and
(ii) may apply as a credit Securities of a series that have been redeemed either at the election of the Company pursuant to the terms of such Securities or through the application of permitted optional sinking fund payments pursuant to the
terms of such Securities, in each case in satisfaction of all or any part of any sinking fund payment with respect to the Securities of such series required to be made pursuant to the terms of such Securities as provided for by the terms of such
series, provided that such Securities have not been previously so credited. Such Securities shall be received and credited for such purpose by the Trustee at the redemption price specified in such Securities for redemption through operation of the
sinking fund and the amount of such sinking fund payment shall be reduced accordingly. 

  
 17.

 Section 3.06 Redemption of Securities for Sinking Fund. 

Not less than 45 days prior to each sinking fund payment date for any series of Securities (unless a shorter period shall be satisfactory
to the Trustee), the Company will deliver to the Trustee an Officer’s Certificate specifying the amount of the next ensuing sinking fund payment for that series pursuant to the terms of the series, the portion thereof, if any, that is to be
satisfied by delivering and crediting Securities of that series pursuant to Section 3.05 and the basis for such credit and will, together with such Officer’s Certificate, deliver to the Trustee any Securities to be so delivered. Not less
than 30 days before each such sinking fund payment date the Trustee shall select the Securities to be redeemed upon such sinking fund payment date in the manner specified in Section 3.02 and cause notice of the redemption thereof to be given in
the name of and at the expense of the Company in the manner provided in Section 3.02. Such notice having been duly given, the redemption of such Securities shall be made upon the terms and in the manner stated in Section 3.03. 

ARTICLE 4 

COVENANTS 

Section 4.01 Payment of Principal, Premium and Interest. 

The Company will duly and punctually pay or cause to be paid the principal of (and premium, if any), interest on, and any redemption price
or repurchase price for the Securities of that series at the time and place and in the manner provided herein and established with respect to such Securities. Payments of the principal of, redemption price for or repurchase price for, the Securities
may be made at the time provided herein and established with respect to such Securities by U.S. dollar check drawn on and mailed to the address of the Securityholder entitled thereto as such address shall appear in the Security Register, or U.S.
dollar wire transfer to, a U.S. dollar account if such Securityholder shall have furnished wire instructions to the Trustee no later than 15 days prior to the relevant payment date. Payments of interest on the Securities may be made at the time
provided herein and established with respect to such Securities by U.S. dollar check mailed to the address of the Securityholder entitled thereto as such address shall appear in the Security Register, or U.S. dollar wire transfer to, a U.S. dollar
account if such Securityholder shall have furnished wire instructions in writing to the Security Registrar and the Trustee no later than 15 days prior to the relevant payment date. 

Section 4.02 Maintenance of Office or Agency. 
 So long as any series of the Securities remain Outstanding, the Company agrees to maintain an office or agency in the continental United States of America with respect to each such series and at such
other location or locations as may be designated as provided in this Section 4.02, where (i) Securities of that series may be presented for payment, (ii) Securities of that series may be presented as herein above authorized for
registration of transfer and exchange, and (iii) notices and demands to or upon the Company in respect of the Securities of that series 

  
 18.

 
and this Indenture may be given or served, such designation to continue with respect to such office or agency until the Company shall, by written notice signed by any officer authorized to sign
an Officer’s Certificate and delivered to the Trustee, designate some other office or agency for such purposes or any of them. If at any time the Company shall fail to maintain any such required office or agency or shall fail to furnish the
Trustee with the address thereof, such presentations, notices and demands may be made or served at the Corporate Trust Office of the Trustee, and the Company hereby appoints the Trustee as its agent to receive all such presentations, notices and
demands. The Company initially appoints the Trustee as its paying agent with respect to the Securities. 
 Section 4.03
Paying Agents. 
 (a) If the Company shall appoint one or more paying agents for all or any series of the Securities,
other than the Trustee, the Company will cause each such paying agent to execute and deliver to the Trustee an instrument in which such agent shall agree with the Trustee, subject to the provisions of this Section: 

(1) that it will hold all sums held by it as such agent for the payment of the principal of (and premium, if any) or interest on
the Securities of that series (whether such sums have been paid to it by the Company or by any other obligor of such Securities) in trust for the benefit of the Persons entitled thereto; 

(2) that it will give the Trustee notice of any failure by the Company (or by any other obligor of such Securities) to make any
payment of the principal of (and premium, if any) or interest on the Securities of that series when the same shall be due and payable; 
 (3) that it will, at any time during the continuance of any failure referred to in the preceding paragraph (a)(2) above, upon the written request of the Trustee, forthwith pay to the Trustee all
sums so held in trust by such paying agent; and 
 (4) that it will perform all other duties of paying agent as set
forth in this Indenture. 
 (b) If the Company shall act as its own paying agent with respect to any series of the
Securities, it will on or before each due date of the principal of (and premium, if any) or interest on Securities of that series, set aside, segregate and hold in trust for the benefit of the Persons entitled thereto a sum sufficient to pay such
principal (and premium, if any) or interest so becoming due on Securities of that series until such sums shall be paid to such Persons or otherwise disposed of as herein provided and will promptly notify the Trustee of such action, or any failure
(by it or any other obligor on such Securities) to take such action. Whenever the Company shall have one or more paying agents for any series of Securities, it will, prior to each due date of the principal of (and premium, if any) or interest on any
Securities of that series, deposit with the paying agent a sum sufficient to pay the principal (and premium, if any) or interest so becoming due, such sum to be held in trust for the benefit of the Persons entitled to such principal, premium or
interest, and (unless such paying agent is the Trustee) the Company will promptly notify the Trustee of this action or failure so to act. 

  
 19.

 (c) Notwithstanding anything in this Section to the contrary, (i) the agreement
to hold sums in trust as provided in this Section is subject to the provisions of Section 11.05, and (ii) the Company may at any time, for the purpose of obtaining the satisfaction and discharge of this Indenture or for any other purpose,
pay, or direct any paying agent to pay, to the Trustee all sums held in trust by the Company or such paying agent, such sums to be held by the Trustee upon the same terms and conditions as those upon which such sums were held by the Company or such
paying agent; and, upon such payment by the Company or any paying agent to the Trustee, the Company or such paying agent shall be released from all further liability with respect to such money. 

Section 4.04 Appointment to Fill Vacancy in Office of Trustee. 

The Company, whenever necessary to avoid or fill a vacancy in the office of Trustee, will appoint, in the manner provided in
Section 7.10, a Trustee, so that there shall at all times be a Trustee hereunder. 
 Section 4.05 Compliance with
Consolidation Provisions. 
 The Company will not, while any of the Securities remain Outstanding, consolidate with or merge
into any other Person, in either case where the Company is not the survivor of such transaction, or sell or convey all or substantially all of its property to any other Person unless the provisions of Article Ten hereof are complied with.

 ARTICLE 5 
 SECURITYHOLDERS’ LISTS AND REPORTS BY THE COMPANY AND THE TRUSTEE 

Section 5.01 Company to Furnish Trustee Names and Addresses of Securityholders. 

The Company will furnish or cause to be furnished to the Trustee (a) within 15 days after each regular record date (as defined in
Section 2.03) a list, in such form as the Trustee may reasonably require, of the names and addresses of the holders of each series of Securities as of such regular record date, provided that the Company shall not be obligated to furnish or
cause to furnish such list at any time that the list shall not differ in any respect from the most recent list furnished to the Trustee by the Company and (b) at such other times as the Trustee may request in writing within 30 days after the
receipt by the Company of any such request, a list of similar form and content as of a date not more than 15 days prior to the time such list is furnished; provided, however, that, in either case, no such list need be furnished for any series for
which the Trustee shall be the Security Registrar. 
 Section 5.02 Preservation Of Information; Communications With
Securityholders. 
 (a) The Trustee shall preserve, in as current a form as is reasonably practicable, all information
as to the names and addresses of the holders of Securities contained in the most recent list furnished to it as provided in Section 5.01 and as to the names and addresses of holders of Securities received by the Trustee in its capacity as
Security Registrar (if acting in such capacity). 

  
 20.

 (b) The Trustee may destroy any list furnished to it as provided in Section 5.01
upon receipt of a new list so furnished. 
 (c) Securityholders may communicate as provided in Section 312(b) of the
Trust Indenture Act with other Securityholders with respect to their rights under this Indenture or under the Securities, and, in connection with any such communications, the Trustee shall satisfy its obligations under Section 312(b) of the
Trust Indenture Act in accordance with the provisions of Section 312(b) of the Trust Indenture Act. 
 Section 5.03
Reports by the Company. 
 (a) The Company covenants and agrees to provide (which delivery may be via electronic mail)
to the Trustee within 30 days, after the Company files the same with the Commission, copies of the annual reports and of the information, documents and other reports (or copies of such portions of any of the foregoing as the Commission may from time
to time by rules and regulations prescribe) that the Company is required to file with the Commission pursuant to Section 13 or Section 15(d) of the Exchange Act; provided, however, the Company shall not be required to deliver to the
Trustee any correspondence filed with the SEC or any materials for which the Company has sought and received confidential treatment by the Commission; and provided further, that so long as such filings by the Company are available on the
Commission’s Electronic Data Gathering, Analysis and Retrieval System (EDGAR), or any successor system, such filings shall be deemed to have been filed with the Trustee for purposes hereof without any further action required by the Company;
provided, however, that the Trustee shall have no responsibility to determine whether such filing has occurred. For the avoidance of doubt, a failure by the Company to file annual reports, information and other reports with the SEC within the time
period prescribed thereof by the Commission shall not be deemed a breach of this Section 5.03. 
 (b) Delivery of
reports, information and documents to the Trustee under Section 5.03 is for informational purposes only and the information and the Trustee’s receipt of the foregoing shall not constitute constructive notice of any information contained
therein, or determinable from information contained therein including the Company’s compliance with any of their covenants thereunder (as to which the Trustee is entitled to rely exclusively on an Officer’s Certificate). 

Section 5.04 Reports by the Trustee. 
 (a) If required by Section 313(a) of the Trust Indenture Act, the Trustee, within sixty (60) days after each March 15, commencing March 15, 2013, shall transmit by mail, first
class postage prepaid, to the Securityholders, as their names and addresses appear upon the Security Register, a brief report dated as of such March 15, which complies with Section 313(a) of the Trust Indenture Act. 

  
 21.

 (b) The Trustee shall comply with Section 313(b) and 313(c) of the Trust
Indenture Act. 
 (c) A copy of each such report shall, at the time of such transmission to Securityholders, be filed by
the Trustee with the Company, with each securities exchange upon which any Securities are listed (if so listed) and also with the Commission. The Company agrees to notify the Trustee when any Securities become listed on any securities exchange.

 ARTICLE 6 
 REMEDIES OF THE TRUSTEE AND SECURITYHOLDERS ON EVENT OF DEFAULT 

Section 6.01 Events of Default. 
 (a) Whenever used herein with respect to Securities of a particular series, “Event of Default” means any one or more of the following events that has occurred and is continuing:

 (1) the Company defaults in the payment of any installment of interest upon any of the Securities of that series, as
and when the same shall become due and payable, and such default continues for a period of 90 days; provided, however, that a valid extension of an interest payment period by the Company in accordance with the terms of any indenture supplemental
hereto shall not constitute a default in the payment of interest for this purpose; 
 (2) the Company defaults in the
payment of the principal of (or premium, if any, on) any of the Securities of that series as and when the same shall become due and payable whether at maturity, upon redemption, by declaration or otherwise, or in any payment required by any sinking
or analogous fund established with respect to that series; provided, however, that a valid extension of the maturity of such Securities in accordance with the terms of any indenture supplemental hereto shall not constitute a default in the payment
of principal or premium, if any; 
 (3) the Company fails to observe or perform any other of its covenants or agreements
with respect to that series contained in this Indenture or otherwise established with respect to that series of Securities pursuant to Section 2.01 hereof (other than a covenant or agreement that has been expressly included in this Indenture
solely for the benefit of one or more series of Securities other than such series) for a period of 90 days after the date on which written notice of such failure, requiring the same to be remedied and stating that such notice is a “Notice of
Default” hereunder, shall have been given to the Company by the Trustee, by registered or certified mail, or to the Company and the Trustee by the holders of at least 25% in principal amount of the Securities of that series at the time
Outstanding; 
 (4) the Company pursuant to or within the meaning of any Bankruptcy Law (i) commences a voluntary
case, (ii) consents to the entry of an order for relief against it in an involuntary case, (iii) consents to the appointment of a Custodian of it or for all or substantially all of its property or (iv) makes a general assignment for
the benefit of its creditors; or 

  
 22.

 (5) a court of competent jurisdiction enters an order under any Bankruptcy Law that
(i) is for relief against the Company in an involuntary case, (ii) appoints a Custodian of the Company for all or substantially all of its property or (iii) orders the liquidation of the Company, and the order or decree remains
unstayed and in effect for 90 days. 
 (b) In each and every such case (other than an Event of Default specified in
clause (4) or clause (5) above), unless the principal of all the Securities of that series shall have already become due and payable, either the Trustee or the holders of not less than 25% in aggregate principal amount of the Securities of
that series then Outstanding hereunder, by notice in writing to the Company (and to the Trustee if given by such Securityholders), may declare the principal of (and premium, if any, on) and accrued and unpaid interest on all the Securities of that
series to be due and payable immediately, and upon any such declaration the same shall become and shall be immediately due and payable. If an Event of Default specified in clause (4) or clause (5) above occurs, the principal of and accrued
and unpaid interest on all the Securities of that series shall automatically be immediately due and payable without any declaration or other act on the part of the Trustee or the holders of the Securities. 

(c) At any time after the principal of (and premium, if any, on) and accrued and unpaid interest on the Securities of that series
shall have been so declared due and payable, and before any judgment or decree for the payment of the moneys due shall have been obtained or entered as hereinafter provided, the holders of a majority in aggregate principal amount of the Securities
of that series then Outstanding hereunder, by written notice to the Company and the Trustee, may rescind and annul such declaration and its consequences if: (i) the Company has paid or deposited with the Trustee a sum sufficient to pay all
matured installments of interest upon all the Securities of that series and the principal of (and premium, if any, on) any and all Securities of that series that shall have become due otherwise than by acceleration (with interest upon such principal
and premium, if any, and, to the extent that such payment is enforceable under applicable law, upon overdue installments of interest, at the rate per annum expressed in the Securities of that series to the date of such payment or deposit) and the
amount payable to the Trustee under Section 7.06, and (ii) any and all Events of Default under the Indenture with respect to such series, other than the nonpayment of principal on (and premium, if any, on) and accrued and unpaid interest
on Securities of that series that shall not have become due by their terms, shall have been remedied or waived as provided in Section 6.06. 
 No such rescission and annulment shall extend to or shall affect any subsequent default or impair any right consequent thereon. 
 (d) In case the Trustee shall have proceeded to enforce any right with respect to Securities of that series under this Indenture and such proceedings shall have been discontinued or abandoned
because of such rescission or annulment or for any other reason or shall have been determined adversely to the Trustee, then and in every such case, subject to any determination in such proceedings, the Company and the Trustee shall be restored
respectively to their former positions and rights hereunder, and all rights, remedies and powers of the Company and the Trustee shall continue as though no such proceedings had been taken. 

  
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 Section 6.02 Collection of Indebtedness and Suits for Enforcement by Trustee.

 (a) The Company covenants that (i) in case it shall default in the payment of any installment of interest on any
of the Securities of a series, or in any payment required by any sinking or analogous fund established with respect to that series as and when the same shall have become due and payable, and such default shall have continued for a period of 90 days,
or (ii) in case it shall default in the payment of the principal of (or premium, if any, on) any of the Securities of a series when the same shall have become due and payable, whether upon maturity of the Securities of a series or upon
redemption or upon declaration or otherwise then, upon demand of the Trustee, the Company will pay to the Trustee, for the benefit of the holders of the Securities of that series, the whole amount that then shall have been become due and payable on
all such Securities for principal (and premium, if any) or interest, or both, as the case may be, with interest upon the overdue principal (and premium, if any) and (to the extent that payment of such interest is enforceable under applicable law)
upon overdue installments of interest at the rate per annum expressed in the Securities of that series; and, in addition thereto, such further amount as shall be sufficient to cover the costs and expenses of collection, and the amount payable to the
Trustee under Section 7.06. 
 (b) If the Company shall fail to pay such amounts forthwith upon such demand, the
Trustee, in its own name and as trustee of an express trust, shall be entitled and empowered to institute any action or proceedings at law or in equity for the collection of the sums so due and unpaid, and may prosecute any such action or proceeding
to judgment or final decree, and may enforce any such judgment or final decree against the Company or other obligor upon the Securities of that series and collect the moneys adjudged or decreed to be payable in the manner provided by law or equity
out of the property of the Company or other obligor upon the Securities of that series, wherever situated. 
 (c) In case
of any receivership, insolvency, liquidation, bankruptcy, reorganization, readjustment, arrangement, composition or judicial proceedings affecting the Company, or its creditors or property, the Trustee shall have power to intervene in such
proceedings and take any action therein that may be permitted by the court and shall (except as may be otherwise provided by law) be entitled to file such proofs of claim and other papers and documents as may be necessary or advisable in order to
have the claims of the Trustee and of the holders of Securities of such series allowed for the entire amount due and payable by the Company under the Indenture at the date of institution of such proceedings and for any additional amount that may
become due and payable by the Company after such date, and to collect and receive any moneys or other property payable or deliverable on any such claim, and to distribute the same after the deduction of the amount payable to the Trustee under
Section 7.06; and any receiver, assignee or trustee in bankruptcy or reorganization is hereby authorized by each of the holders of Securities of such series to make such payments to the Trustee, and, in the event that the Trustee shall consent
to the making of such payments directly to such Securityholders, to pay to the Trustee any amount due it under Section 7.06. 
 (d) All rights of action and of asserting claims under this Indenture, or under any of the terms established with respect to Securities of that series, may be enforced by the Trustee without the
possession of any of such Securities, or the production thereof at any trial or other proceeding relative thereto, and any such suit or proceeding instituted by the Trustee shall be 

  
 24.

 
brought in its own name as trustee of an express trust, and any recovery of judgment shall, after provision for payment to the Trustee of any amounts due under Section 7.06, be for the
ratable benefit of the holders of the Securities of such series. 
 In case of an Event of Default hereunder, the Trustee may in
its discretion proceed to protect and enforce the rights vested in it by this Indenture by such appropriate judicial proceedings as the Trustee shall deem most effectual to protect and enforce any of such rights, either at law or in equity or in
bankruptcy or otherwise, whether for the specific enforcement of any covenant or agreement contained in the Indenture or in aid of the exercise of any power granted in this Indenture, or to enforce any other legal or equitable right vested in the
Trustee by this Indenture or by law. 
 Nothing contained herein shall be deemed to authorize the Trustee to authorize or
consent to or accept or adopt on behalf of any Securityholder any plan of reorganization, arrangement, adjustment or composition affecting the Securities of that series or the rights of any holder thereof or to authorize the Trustee to vote in
respect of the claim of any Securityholder in any such proceeding. 
 Section 6.03 Application of Moneys Collected.

 Any moneys collected by the Trustee pursuant to this Article with respect to a particular series of Securities shall be
applied in the following order, at the date or dates fixed by the Trustee and, in case of the distribution of such moneys on account of principal (or premium, if any) or interest, upon presentation of the Securities of that series, and notation
thereon of the payment, if only partially paid, and upon surrender thereof if fully paid: 
 FIRST: To the payment of reasonable
costs and expenses of collection and of all amounts payable to the Trustee under Section 7.06; 
 SECOND: To the payment of
the amounts then due and unpaid upon Securities of such series for principal (and premium, if any) and interest, in respect of which or for the benefit of which such money has been collected, ratably, without preference or priority of any kind,
according to the amounts due and payable on such Securities for principal (and premium, if any) and interest, respectively; and 

THIRD: To the payment of the remainder, if any, to the Company or any other Person lawfully entitled thereto. 

Section 6.04 Limitation on Suits. 
 No holder of any Security of any series shall have any right by virtue or by availing of any provision of this Indenture to institute any suit, action or proceeding in equity or at law upon or under or
with respect to this Indenture or for the appointment of a receiver or trustee, or for any other remedy hereunder, unless (i) such holder previously shall have given to the Trustee written notice of an Event of Default and of the continuance
thereof with respect to the Securities of such series specifying such Event of Default, as hereinbefore provided; (ii) the holders of not less than 25% in aggregate principal amount of the Securities of such series then Outstanding shall have

  
 25.

 
made written request upon the Trustee to institute such action, suit or proceeding in its own name as Trustee hereunder; (iii) such holder or holders shall have offered to the Trustee
indemnity reasonably satisfactory to the Trustee against the costs, expenses and liabilities to be incurred therein or thereby; (iv) the Trustee for 90 days after its receipt of such notice, request and offer of indemnity, shall have failed to
institute any such action, suit or proceeding and (v) during such 90 day period, the holders of a majority in principal amount of the Securities of that series do not give the Trustee a direction inconsistent with the request. 

Notwithstanding anything contained herein to the contrary or any other provisions of this Indenture, the right of any holder of any
Security to receive payment of the principal of (and premium, if any) and interest on such Security, as therein provided, on or after the respective due dates expressed in such Security (or in the case of redemption, on the redemption date), or to
institute suit for the enforcement of any such payment on or after such respective dates or redemption date, shall not be impaired or affected without the consent of such holder and by accepting a Security hereunder it is expressly understood,
intended and covenanted by the taker and holder of every Security of such series with every other such taker and holder and the Trustee, that no one or more holders of Securities of such series shall have any right in any manner whatsoever by virtue
or by availing of any provision of this Indenture to affect, disturb or prejudice the rights of the holders of any other of such Securities, or to obtain or seek to obtain priority over or preference to any other such holder, or to enforce any right
under this Indenture, except in the manner herein provided and for the equal, ratable and common benefit of all holders of Securities of such series. For the protection and enforcement of the provisions of this Section, each and every Securityholder
and the Trustee shall be entitled to such relief as can be given either at law or in equity. 
 Section 6.05 Rights and
Remedies Cumulative; Delay or Omission Not Waiver. 
 (a) Except as otherwise provided in Section 2.07, all
powers and remedies given by this Article to the Trustee or to the Securityholders shall, to the extent permitted by law, be deemed cumulative and not exclusive of any other powers and remedies available to the Trustee or the holders of the
Securities, by judicial proceedings or otherwise, to enforce the performance or observance of the covenants and agreements contained in this Indenture or otherwise established with respect to such Securities. 

(b) No delay or omission of the Trustee or of any holder of any of the Securities to exercise any right or power accruing upon any
Event of Default occurring and continuing as aforesaid shall impair any such right or power, or shall be construed to be a waiver of any such default or an acquiescence therein; and, subject to the provisions of Section 6.04, every power and
remedy given by this Article or by law to the Trustee or the Securityholders may be exercised from time to time, and as often as shall be deemed expedient, by the Trustee or by the Securityholders. 

Section 6.06 Control by Securityholders. 
 The holders of a majority in aggregate principal amount of the Securities of any series at the time Outstanding, determined in accordance with Section 8.04, shall have the right to direct the time,
method and place of conducting any proceeding for any remedy available to the Trustee, 

  
 26.

 
or exercising any trust or power conferred on the Trustee with respect to such series; provided, however, that such direction shall not be in conflict with any rule of law or with this Indenture
or subject the Trustee in its sole discretion to personal liability. Subject to the provisions of Section 7.01, the Trustee shall have the right to decline to follow any such direction if the Trustee in good faith shall, by a Responsible
Officer or officers of the Trustee, determine that the proceeding so directed, subject to the Trustee’s duties under the Trust Indenture Act, would involve the Trustee in personal liability or might be unduly prejudicial to the Securityholders
not involved in the proceeding. The holders of a majority in aggregate principal amount of the Securities of any series at the time Outstanding affected thereby, determined in accordance with Section 8.04, may on behalf of the holders of all of
the Securities of such series waive any past default in the performance of any of the covenants contained herein or established pursuant to Section 2.01 with respect to such series and its consequences, except a default in the payment of the
principal of, or premium, if any, or interest on, any of the Securities of that series as and when the same shall become due by the terms of such Securities otherwise than by acceleration (unless such default has been cured and a sum sufficient to
pay all matured installments of interest and principal and any premium has been deposited with the Trustee (in accordance with Section 6.01(c)). Upon any such waiver, the default covered thereby shall be deemed to be cured for all purposes of
this Indenture and the Company, the Trustee and the holders of the Securities of such series shall be restored to their former positions and rights hereunder, respectively; but no such waiver shall extend to any subsequent or other default or impair
any right consequent thereon. 
 Section 6.07 Undertaking to Pay Costs. 

All parties to this Indenture agree, and each holder of any Securities by such holder’s acceptance thereof shall be deemed to have
agreed, that any court may in its discretion require, in any suit for the enforcement of any right or remedy under this Indenture, or in any suit against the Trustee for any action taken or omitted by it as Trustee, the filing by any party litigant
in such suit of an undertaking to pay the costs of such suit, and that such court may in its discretion assess reasonable costs, including reasonable attorneys’ fees and expenses, against any party litigant in such suit, having due regard to
the merits and good faith of the claims or defenses made by such party litigant; but the provisions of this Section shall not apply to any suit instituted by the Trustee, to any suit instituted by any Securityholder, or group of Securityholders,
holding more than 10% in aggregate principal amount of the Outstanding Securities of any series, or to any suit instituted by any Securityholder for the enforcement of the payment of the principal of (or premium, if any) or interest on any Security
of such series, on or after the respective due dates expressed in such Security or established pursuant to this Indenture. 

ARTICLE 7 

CONCERNING THE TRUSTEE 
 Section 7.01 Certain Duties and Responsibilities of Trustee. 
 (a)
The Trustee, prior to the occurrence of an Event of Default with respect to the Securities of a series and after the curing of all Events of Default with respect to the Securities of 

  
 27.

 
that series that may have occurred, shall undertake to perform with respect to the Securities of such series such duties and only such duties as are specifically set forth in this Indenture, and
no implied covenants shall be read into this Indenture against the Trustee. In case an Event of Default with respect to the Securities of a series has occurred (that has not been cured or waived), the Trustee shall exercise with respect to
Securities of that series such of the rights and powers vested in it by this Indenture, and use the same degree of care and skill in their exercise, as a prudent person would exercise or use under the circumstances in the conduct of his or her own
affairs. 
 (b) No provision of this Indenture shall be construed to relieve the Trustee from liability for its own
negligent action, its own negligent failure to act, or its own willful misconduct, except that: 
 (i) prior to the
occurrence of an Event of Default with respect to the Securities of a series and after the curing or waiving of all such Events of Default with respect to that series that may have occurred: 

(A) the duties and obligations of the Trustee shall with respect to the Securities of such series be determined solely by the
express provisions of this Indenture, and the Trustee shall not be liable with respect to the Securities of such series except for the performance of such duties and obligations as are specifically set forth in this Indenture, and no implied
covenants or obligations shall be read into this Indenture against the Trustee; and 
 (B) in the absence of bad faith
on the part of the Trustee, the Trustee may with respect to the Securities of such series conclusively rely, as to the truth of the statements and the correctness of the opinions expressed therein, upon any certificates or opinions furnished to the
Trustee and conforming to the requirements of this Indenture; but in the case of any such certificates or opinions that by any provision hereof are specifically required to be furnished to the Trustee, the Trustee shall be under a duty to examine
the same to determine whether or not they conform to the requirements of this Indenture; 
 (ii) the Trustee shall not be
liable for any error of judgment made in good faith by a Responsible Officer or Responsible Officers of the Trustee, unless it shall be proved that the Trustee was negligent in ascertaining the pertinent facts; 

(iii) the Trustee shall not be liable with respect to any action taken or omitted to be taken by it in good faith in accordance
with the direction of the holders of not less than a majority in principal amount of the Securities of any series at the time Outstanding relating to the time, method and place of conducting any proceeding for any remedy available to the Trustee, or
exercising any trust or power conferred upon the Trustee under this Indenture with respect to the Securities of that series; and 
 (iv) none of the provisions contained in this Indenture shall require the Trustee to expend or risk its own funds or otherwise incur personal financial liability in the performance of any of its
duties or in the exercise of any of its rights or powers if there is reasonable ground for believing that the repayment of such funds or liability is not reasonably assured to it under the terms of this Indenture or adequate indemnity against such
risk is not reasonably assured to it. 

  
 28.

 Section 7.02 Certain Rights of Trustee. 

Except as otherwise provided in Section 7.01: 
 (a) The Trustee may rely and shall be protected in acting or refraining from acting upon any resolution, certificate, statement, instrument, opinion, report, notice, request, consent, order,
approval, bond, security or other paper or document believed by it to be genuine and to have been signed or presented by the proper party or parties; 
 (b) Any request, direction, order or demand of the Company mentioned herein shall be sufficiently evidenced by a Board Resolution or an instrument signed in the name of the Company by any
authorized officer of the Company (unless other evidence in respect thereof is specifically prescribed herein); 
 (c)
The Trustee may consult with counsel and the opinion or written advice of such counsel or, if requested, any Opinion of Counsel shall be full and complete authorization and protection in respect of any action taken or suffered or omitted
hereunder in good faith and in reliance thereon; 
 (d) The Trustee shall be under no obligation to exercise any of the
rights or powers vested in it by this Indenture at the request, order or direction of any of the Securityholders pursuant to the provisions of this Indenture, unless such Securityholders shall have offered to the Trustee reasonable security or
indemnity against the costs, expenses and liabilities that may be incurred therein or thereby; nothing contained herein shall, however, relieve the Trustee of the obligation, upon the occurrence of an Event of Default with respect to a series of the
Securities (that has not been cured or waived), to exercise with respect to Securities of that series such of the rights and powers vested in it by this Indenture, and to use the same degree of care and skill in their exercise, as a prudent person
would exercise or use under the circumstances in the conduct of his or her own affairs; 
 (e) The Trustee shall not be
liable for any action taken or omitted to be taken by it in good faith and believed by it to be authorized or within the discretion or rights or powers conferred upon it by this Indenture; 

(f) The Trustee shall not be bound to make any investigation into the facts or matters stated in any resolution, certificate,
statement, instrument, opinion, report, notice, request, consent, order, approval, bond, security, or other papers or documents, unless requested in writing so to do by the holders of not less than a majority in principal amount of the Outstanding
Securities of the particular series affected thereby (determined as provided in Section 8.04); provided, however, that if the payment within a reasonable time to the Trustee of the costs, expenses or liabilities likely to be incurred by it in
the making of such investigation is, in the opinion of the Trustee, not reasonably assured to the Trustee by the security afforded to it by the terms of this Indenture, the Trustee may require reasonable indemnity against such costs, expenses or
liabilities as a condition to so proceeding. The reasonable expense of every such examination shall be paid by the Company or, if paid by the Trustee, shall be repaid by the Company upon demand; 

  
 29.

 (g) The Trustee may execute any of the trusts or powers hereunder or perform any
duties hereunder either directly or by or through agents or attorneys and the Trustee shall not be responsible for any misconduct or negligence on the part of any agent or attorney appointed with due care by it hereunder; 

(h) In no event shall the Trustee be responsible or liable for any failure or delay in the performance of its obligations
hereunder arising out of or caused by, directly or indirectly, forces beyond its control, including, without limitation, strikes, work stoppages, accidents, acts of war or terrorism, civil or military disturbances, nuclear or natural catastrophes or
acts of God, and interruptions, loss or malfunctions of utilities, communications or computer (software and hardware) services; it being understood that the Trustee shall use reasonable efforts which are consistent with accepted practices in the
banking industry to resume performance as soon as practicable under the circumstances; 
 (i) In no event shall the
Trustee be responsible or liable for special, indirect, punitive, or consequential loss or damage of any kind whatsoever (including, but not limited to, loss of profit) irrespective of whether the Trustee has been advised of the likelihood of such
loss or damage and regardless of the form of action; and 
 (j) The Trustee agrees to accept and act upon instructions or
directions pursuant to this Indenture sent by unsecured e-mail, facsimile transmission or other similar unsecured electronic methods; provided, however, that (a) the party providing such written instructions, subsequent to such transmission of
written instructions, shall provide the originally executed instructions or directions to the Trustee in a timely manner, and (b) such originally executed instructions or directions shall be signed by an authorized representative of the party
providing such instructions or directions. If the party elects to give the Trustee e-mail or facsimile instructions (or instructions by a similar electronic method) and the Trustee in its sole discretion elects to act upon such instructions, the
Trustee’s understanding of such instructions shall be deemed controlling. The Trustee shall not be liable for any losses, costs or expenses arising directly or indirectly from the Trustee’s reliance upon and compliance with such
instructions notwithstanding such instructions conflict or are inconsistent with a subsequent written instruction. The party providing electronic instructions agrees to assume all risks arising out of the use of such electronic methods to submit
instructions and directions to the Trustee, including without limitation the risk of the Trustee acting on unauthorized instructions, and the risk or interception and misuse by third parties. 

(k) Before the Trustee acts or refrains from acting, it may require an Officer’s Certificate and an Opinion of Counsel. The
Trustee shall not be liable for any action it takes or omits to take in good faith in reliance on such certificate or opinion. 

In addition, the Trustee shall not be deemed to have knowledge of an Event of Default other than an Event of Default relating to the
failure to pay the interest on, or the principal of, the Securities, until the Trustee shall have received written notification in the manner set forth in this Indenture or a Responsible Officer of the Trustee shall have obtained actual knowledge.

  
 30.

 Section 7.03 Trustee Not Responsible for Recitals or Issuance or Securities.

 (a) The recitals contained herein and in the Securities shall be taken as the statements of the Company, and the
Trustee assumes no responsibility for the correctness of the same. 
 (b) The Trustee makes no representations as to the
validity or sufficiency of this Indenture or of the Securities. 
 (c) The Trustee shall not be accountable for the use
or application by the Company of any of the Securities or of the proceeds of such Securities, or for the use or application of any moneys paid over by the Trustee in accordance with any provision of this Indenture or established pursuant to
Section 2.01, or for the use or application of any moneys received by any paying agent other than the Trustee. 

Section 7.04 May Hold Securities. 
 The Trustee or any paying agent or Security Registrar, in its individual or any other capacity, may become the owner or pledgee of Securities with the same rights it would have if it were not Trustee,
paying agent or Security Registrar. 
 Section 7.05 Moneys Held in Trust. 

Subject to the provisions of Section 11.05, all moneys received by the Trustee shall, until used or applied as herein provided, be
held in trust for the purposes for which they were received, but need not be segregated from other funds except to the extent required by law. The Trustee shall be under no liability for interest on any moneys received by it hereunder except such as
it may agree to in writing with the Company to pay thereon. 
 Section 7.06 Compensation and Reimbursement.

 (a) The Company covenants and agrees to pay to the Trustee, and the Trustee shall be entitled to, such compensation
(which shall not be limited by any provision of law in regard to the compensation of a trustee of an express trust) as the Company and the Trustee may from time to time agree in writing, for all services rendered by it in the execution of the trusts
hereby created and in the exercise and performance of any of the powers and duties hereunder of the Trustee, and, except as otherwise expressly provided herein, the Company will pay or reimburse the Trustee upon its request for all reasonable
expenses, disbursements and advances incurred or made by the Trustee in accordance with any of the provisions of this Indenture (including the reasonable compensation and the expenses and disbursements of its counsel and of all Persons not regularly
in its employ), except any such expense, disbursement or advance as may arise from its negligence or willful misconduct and except as the Company and Trustee may from time to time agree in writing. The Company also covenants to indemnify the Trustee
(and its officers, agents, directors and employees) for, and to hold it harmless against, any loss, liability or expense incurred without negligence or willful misconduct on the part of the Trustee and arising out of or in connection with the
acceptance or administration of this trust, including the reasonable costs and expenses of defending itself against any claim of liability in the premises. 

  
 31.

 (b) The obligations of the Company under this Section to compensate and indemnify the
Trustee and to pay or reimburse the Trustee for reasonable expenses, disbursements and advances shall constitute additional indebtedness hereunder. Such additional indebtedness shall be secured by a lien prior to that of the Securities upon all
property and funds held or collected by the Trustee as such, except funds held in trust for the benefit of the holders of particular Securities. 
 (c) To ensure the Company’s payment obligations in this Section, the Trustee shall have a lien prior to the Securities on all funds or property held or collected by the Trustee, except that
held in trust to pay principal of or interest on particular Securities. When the Trustee incurs expenses or renders services in connection with an Event of Default specified in Section 6.01(4) or (5), the expenses (including the reasonable fees
and expenses of its counsel) and the compensation for services in connection therewith are to constitute expenses of administration under any bankruptcy law. The provisions of this Section 7.06 shall survive the termination of this Indenture
and the resignation or removal of the Trustee. 
 Section 7.07 Reliance on Officer’s Certificate. 

Except as otherwise provided in Section 7.01, whenever in the administration of the provisions of this Indenture the Trustee shall
deem it reasonably necessary or desirable that a matter be proved or established prior to taking or suffering or omitting to take any action hereunder, such matter (unless other evidence in respect thereof be herein specifically prescribed) may, in
the absence of negligence or bad faith on the part of the Trustee, be deemed to be conclusively proved and established by an Officer’s Certificate delivered to the Trustee and such certificate, in the absence of negligence or bad faith on the
part of the Trustee, shall be full warrant to the Trustee for any action taken, suffered or omitted to be taken by it under the provisions of this Indenture upon the faith thereof. 

Section 7.08 Disqualification; Conflicting Interests. 

If the Trustee has or shall acquire any “conflicting interest” within the meaning of Section 310(b) of the Trust Indenture
Act, the Trustee and the Company shall in all respects comply with the provisions of Section 310(b) of the Trust Indenture Act. 
 Section 7.09 Corporate Trustee Required; Eligibility. 
 There shall at
all times be a Trustee with respect to the Securities issued hereunder which shall at all times be a corporation organized and doing business under the laws of the United States of America or any state or territory thereof or of the District of
Columbia, or a corporation or other Person permitted to act as trustee by the Commission, authorized under such laws to exercise corporate trust powers, having a combined capital and surplus of at least fifty million U.S. dollars ($50,000,000), and
subject to supervision or examination by federal, state, territorial, or District of Columbia authority. 

  
 32.

 If such corporation or other Person publishes reports of condition at least annually,
pursuant to law or to the requirements of the aforesaid supervising or examining authority, then for the purposes of this Section, the combined capital and surplus of such corporation or other Person shall be deemed to be its combined capital and
surplus as set forth in its most recent report of condition so published. The Company may not, nor may any Person directly or indirectly controlling, controlled by, or under common control with the Company, serve as Trustee. In case at any time the
Trustee shall cease to be eligible in accordance with the provisions of this Section, the Trustee shall resign immediately in the manner and with the effect specified in Section 7.10. 

Section 7.10 Resignation and Removal; Appointment of Successor. 

(a) The Trustee or any successor hereafter appointed may at any time resign with respect to the Securities of one or more series by
giving written notice thereof to the Company and by transmitting notice of resignation by mail, first class postage prepaid, to the Securityholders of such series, as their names and addresses appear upon the Security Register. Upon receiving such
notice of resignation, the Company shall promptly appoint a successor trustee with respect to Securities of such series by written instrument, in duplicate, executed by order of the Board of Directors, one copy of which instrument shall be delivered
to the resigning Trustee and one copy to the successor trustee. If no successor trustee shall have been so appointed and have accepted appointment within 30 days after the mailing of such notice of resignation, the resigning Trustee may petition, at
the expense of the Company, any court of competent jurisdiction for the appointment of a successor trustee with respect to Securities of such series, or any Securityholder of that series who has been a bona fide holder of a Security or Securities
for at least six months may on behalf of himself and all others similarly situated, petition any such court for the appointment of a successor trustee. Such court may thereupon after such notice, if any, as it may deem proper and prescribe, appoint
a successor trustee. 
 (b) In case at any time any one of the following shall occur: 

(i) the Trustee shall fail to comply with the provisions of Section 7.08 after written request therefor by the Company or by
any Securityholder who has been a bona fide holder of a Security or Securities for at least six months; or 
 (ii) the
Trustee shall cease to be eligible in accordance with the provisions of Section 7.09 and shall fail to resign after written request therefor by the Company or by any such Securityholder; or 

(iii) the Trustee shall become incapable of acting, or shall be adjudged a bankrupt or insolvent, or commence a voluntary
bankruptcy proceeding, or a receiver of the Trustee or of its property shall be appointed or consented to, or any public officer shall take charge or control of the Trustee or of its property or affairs for the purpose of rehabilitation,
conservation or liquidation; 
 then, in any such case, the Company may remove the Trustee with respect to all Securities and
appoint a successor trustee by written instrument, in duplicate, executed by order of the Board of Directors, one copy of which instrument shall be delivered to the Trustee so removed 

  
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and one copy to the successor trustee, or any Securityholder who has been a bona fide holder of a Security or Securities for at least six months may, on behalf of that holder and all others
similarly situated, petition any court of competent jurisdiction for the removal of the Trustee and the appointment of a successor trustee. Such court may thereupon after such notice, if any, as it may deem proper and prescribe, remove the Trustee
and appoint a successor trustee. 
 (c) The holders of a majority in aggregate principal amount of the Securities of any
series at the time Outstanding may at any time remove the Trustee with respect to such series by so notifying the Trustee and the Company and may appoint a successor Trustee for such series with the consent of the Company. 

(d) Any resignation or removal of the Trustee and appointment of a successor trustee with respect to the Securities of a series
pursuant to any of the provisions of this Section shall become effective upon acceptance of appointment by the successor trustee as provided in Section 7.11. 
 (e) Any successor trustee appointed pursuant to this Section may be appointed with respect to the Securities of one or more series or all of such series, and at any time there shall be only one
Trustee with respect to the Securities of any particular series. 
 Section 7.11 Acceptance of Appointment By
Successor. 
 (a) In case of the appointment hereunder of a successor trustee with respect to all Securities, every
such successor trustee so appointed shall execute, acknowledge and deliver to the Company and to the retiring Trustee an instrument accepting such appointment, and thereupon the resignation or removal of the retiring Trustee shall become effective
and such successor trustee, without any further act, deed or conveyance, shall become vested with all the rights, powers, trusts and duties of the retiring Trustee; but, on the request of the Company or the successor trustee, such retiring Trustee
shall, upon payment of its charges, execute and deliver an instrument transferring to such successor trustee all the rights, powers, and trusts of the retiring Trustee and shall duly assign, transfer and deliver to such successor trustee all
property and money held by such retiring Trustee hereunder. 
 (b) In case of the appointment hereunder of a successor
trustee with respect to the Securities of one or more (but not all) series, the Company, the retiring Trustee and each successor trustee with respect to the Securities of one or more series shall execute and deliver an indenture supplemental hereto
wherein each successor trustee shall accept such appointment and which (i) shall contain such provisions as shall be necessary or desirable to transfer and confirm to, and to vest in, each successor trustee all the rights, powers, trusts and
duties of the retiring Trustee with respect to the Securities of that or those series to which the appointment of such successor trustee relates, (ii) shall contain such provisions as shall be deemed necessary or desirable to confirm that all
the rights, powers, trusts and duties of the retiring Trustee with respect to the Securities of that or those series as to which the retiring Trustee is not retiring shall continue to be vested in the retiring Trustee, and (iii) shall add to or
change any of the provisions of this Indenture as shall be necessary to provide for or facilitate the administration of the trusts hereunder by more than one Trustee, it being understood that nothing herein or in such supplemental indenture shall
constitute such Trustees co-trustees of the same trust, that each such 

  
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Trustee shall be trustee of a trust or trusts hereunder separate and apart from any trust or trusts hereunder administered by any other such Trustee and that no Trustee shall be responsible for
any act or failure to act on the part of any other Trustee hereunder; and upon the execution and delivery of such supplemental indenture the resignation or removal of the retiring Trustee shall become effective to the extent provided therein, such
retiring Trustee shall with respect to the Securities of that or those series to which the appointment of such successor trustee relates have no further responsibility for the exercise of rights and powers or for the performance of the duties and
obligations vested in the Trustee under this Indenture, and each such successor trustee, without any further act, deed or conveyance, shall become vested with all the rights, powers, trusts and duties of the retiring Trustee with respect to the
Securities of that or those series to which the appointment of such successor trustee relates; but, on request of the Company or any successor trustee, such retiring Trustee shall duly assign, transfer and deliver to such successor trustee, to the
extent contemplated by such supplemental indenture, the property and money held by such retiring Trustee hereunder with respect to the Securities of that or those series to which the appointment of such successor trustee relates. 

(c) Upon request of any such successor trustee, the Company shall execute any and all instruments for more fully and certainly
vesting in and confirming to such successor trustee all such rights, powers and trusts referred to in paragraph (a) or (b) of this Section, as the case may be. 
 (d) No successor trustee shall accept its appointment unless at the time of such acceptance such successor trustee shall be qualified and eligible under this Article. 

(e) Upon acceptance of appointment by a successor trustee as provided in this Section, the Company shall transmit notice of the
succession of such trustee hereunder by mail, first class postage prepaid, to the Securityholders, as their names and addresses appear upon the Security Register. If the Company fails to transmit such notice within ten days after acceptance of
appointment by the successor trustee, the successor trustee shall cause such notice to be transmitted at the expense of the Company. 
 Section 7.12 Merger, Conversion, Consolidation or Succession to Business. 
 Any corporation into which the Trustee may be merged or converted or with which it may be consolidated, or any corporation resulting from any merger, conversion or consolidation to which the Trustee shall
be a party, or any corporation succeeding to all or substantially all the corporate trust business of the Trustee, including the administration of the trust created by this Indenture, shall be the successor of the Trustee hereunder, provided that
such corporation shall be qualified under the provisions of Section 7.08 and eligible under the provisions of Section 7.09, without the execution or filing of any paper or any further act on the part of any of the parties hereto, anything
herein to the contrary notwithstanding. In case any Securities shall have been authenticated, but not delivered, by the Trustee then in office, any successor by merger, conversion or consolidation to such authenticating Trustee may adopt such
authentication and deliver the Securities so authenticated with the same effect as if such successor Trustee had itself authenticated such Securities. 

  
 35.

 Section 7.13 Preferential Collection of Claims Against the Company. 

The Trustee shall comply with Section 311(a) of the Trust Indenture Act, excluding any creditor relationship described in
Section 311(b) of the Trust Indenture Act. A Trustee who has resigned or been removed shall be subject to Section 311(a) of the Trust Indenture Act to the extent included therein. 

Section 7.14 Notice of Default 
 If any Event of Default occurs and is continuing and if such Event of Default is actually known to a Responsible Officer of the Trustee, the Trustee shall mail to each Securityholder in the manner and to
the extent provided in Section 313(c) of the Trust Indenture Act notice of the Event of Default within 90 days after it occurs or, if later, after it is known to a Responsible Officer of the Trustee or written notice of it is received by the
Trustee, unless such Event of Default has been cured; provided, however, that, except in the case of a default in the payment of the principal of (or premium, if any) or interest on any Security, the Trustee shall be protected in withholding
such notice if and so long as the board of directors, the executive committee or a trust committee of directors and/or Responsible Officers of the Trustee in good faith determine that the withholding of such notice is in the interest of the
Securityholders. 
 ARTICLE 8 
 CONCERNING THE SECURITYHOLDERS 
 Section 8.01 Evidence of Action by
Securityholders. 
 Whenever in this Indenture it is provided that the holders of a majority or specified percentage in
aggregate principal amount of the Securities of a particular series may take any action (including the making of any demand or request, the giving of any notice, consent or waiver or the taking of any other action), the fact that at the time of
taking any such action the holders of such majority or specified percentage of that series have joined therein may be evidenced by any instrument or any number of instruments of similar tenor executed by such holders of Securities of that series in
person or by agent or proxy appointed in writing. 
 If the Company shall solicit from the Securityholders of any series any
request, demand, authorization, direction, notice, consent, waiver or other action, the Company may, at its option, as evidenced by an Officer’s Certificate, fix in advance a record date for such series for the determination of Securityholders
entitled to give such request, demand, authorization, direction, notice, consent, waiver or other action, but the Company shall have no obligation to do so. If such a record date is fixed, such request, demand, authorization, direction, notice,
consent, waiver or other action may be given before or after the record date, but only the Securityholders of record at the close of business on the record date shall be deemed to be Securityholders for the purposes of determining whether
Securityholders of the requisite proportion of Outstanding Securities of that series have authorized or agreed or consented to such request, demand, authorization, direction, notice, consent, waiver or other action, and for that purpose the
Outstanding Securities of that series shall be computed as of the record date; provided, however, that no such authorization, agreement or consent by such Securityholders on the record date shall be deemed effective unless it shall become effective
pursuant to the provisions of this Indenture not later than six months after the record date. 

  
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 Section 8.02 Proof of Execution by Securityholders. 

Subject to the provisions of Section 7.01, proof of the execution of any instrument by a Securityholder (such proof will not require
notarization) or his agent or proxy and proof of the holding by any Person of any of the Securities shall be sufficient if made in the following manner: 
 (a) The fact and date of the execution by any such Person of any instrument may be proved in any reasonable manner acceptable to the Trustee. 

(b) The ownership of Securities shall be proved by the Security Register of such Securities or by a certificate of the Security
Registrar thereof. 
 The Trustee may require such additional proof of any matter referred to in this Section as it shall deem necessary.

 Section 8.03 Who May be Deemed Owners. 
 Prior to the due presentment for registration of transfer of any Security, the Company, the Trustee, any paying agent and any Security Registrar may deem and treat the Person in whose name such Security
shall be registered upon the books of the Security Registrar as the absolute owner of such Security (whether or not such Security shall be overdue and notwithstanding any notice of ownership or writing thereon made by anyone other than the Security
Registrar) for the purpose of receiving payment of or on account of the principal of, premium, if any, and (subject to Section 2.03) interest on such Security and for all other purposes; and neither the Company nor the Trustee nor any paying
agent nor any Security Registrar shall be affected by any notice to the contrary. 
 Section 8.04 Certain Securities
Owned by Company Disregarded. 
 In determining whether the holders of the requisite aggregate principal amount of Securities
of a particular series have concurred in any direction, consent or waiver under this Indenture, the Securities of that series that are owned by the Company or any other obligor on the Securities of that series or by any Person directly or indirectly
controlling or controlled by or under common control with the Company or any other obligor on the Securities of that series shall be disregarded and deemed not to be Outstanding for the purpose of any such determination, except that for the purpose
of determining whether the Trustee shall be protected in relying on any such direction, consent or waiver, only Securities of such series that the Trustee actually knows are so owned shall be so disregarded. The Securities so owned that have been
pledged in good faith may be regarded as Outstanding for the purposes of this Section, if the pledgee shall establish to the satisfaction of the Trustee the pledgee’s right so to act with respect to such Securities and that the pledgee is not a
Person directly or indirectly controlling or controlled by or under direct or indirect common control with the Company or any such other obligor. In case of a dispute as to such right, any decision by the Trustee taken upon the advice of counsel
shall be full protection to the Trustee. 

  
 37.

 Section 8.05 Actions Binding on Future Securityholders. 

At any time prior to (but not after) the evidencing to the Trustee, as provided in Section 8.01, of the taking of any action by the
holders of the majority or percentage in aggregate principal amount of the Securities of a particular series specified in this Indenture in connection with such action, any holder of a Security of that series that is shown by the evidence to be
included in the Securities the holders of which have consented to such action may, by filing written notice with the Trustee, and upon proof of holding as provided in Section 8.02, revoke such action so far as concerns such Security. Except as
aforesaid any such action taken by the holder of any Security shall be conclusive and binding upon such holder and upon all future holders and owners of such Security, and of any Security issued in exchange therefor, on registration of transfer
thereof or in place thereof, irrespective of whether or not any notation in regard thereto is made upon such Security. Any action taken by the holders of the majority or percentage in aggregate principal amount of the Securities of a particular
series specified in this Indenture in connection with such action shall be conclusively binding upon the Company, the Trustee and the holders of all the Securities of that series. 

ARTICLE 9 

SUPPLEMENTAL INDENTURES 
 Section 9.01 Supplemental Indentures Without the Consent of Securityholders. 
 In addition to any supplemental indenture otherwise authorized by this Indenture, the Company and the Trustee may from time to time and at any time enter into an indenture or indentures supplemental
hereto (which shall conform to the provisions of the Trust Indenture Act as then in effect), without the consent of any Securityholders, for one or more of the following purposes: 

(a) to cure any ambiguity, defect, or inconsistency in this Indenture or in the Securities of any series; 

(b) to comply with Article Ten; 
 (c) to provide for uncertificated Securities in addition to or in place of certificated Securities; 
 (d) to add to the covenants, restrictions, conditions or provisions such new covenants, restrictions, conditions or provisions for the benefit of the Securityholders, to make the occurrence, or the
occurrence and the continuance, of a default in any such additional covenants, restrictions, conditions or provisions an Event of Default, or to surrender any right or power conferred upon the Company in this Indenture; 

  
 38.

 (e) to add to, delete from, or revise the conditions, limitations, and restrictions
on the authorized amount, terms, or purposes of issue, authentication, and delivery of Securities, as set forth in this Indenture; 
 (f) to make any change that does not adversely affect the rights of any Securityholder in any material respect; 
 (g) to provide for the issuance of and establish the form and terms and conditions of the Securities of any series as provided in Section 2.01, to establish the form of any certifications
required to be furnished pursuant to the terms of this Indenture or any series of Securities, or to add to the rights of the holders of any series of Securities; 
 (h) to evidence and provide for the acceptance of appointment under this Indenture by a successor trustee; or 
 (i) to comply with any requirements of the Commission with the qualification of this Indenture under the Trust Indenture Act. 

The Trustee is hereby authorized to join with the Company in the execution of any such supplemental indenture, and to make any further
appropriate agreements and stipulations that may be therein contained, but the Trustee shall not be obligated to enter into any such supplemental indenture that affects the Trustee’s own rights, duties or immunities under this Indenture or
otherwise. 
 Any supplemental indenture authorized by the provisions of this Section may be executed by the Company and the
Trustee without the consent of the holders of any of the Securities at the time Outstanding, notwithstanding any of the provisions of Section 9.02. 
 Section 9.02 Supplemental Indentures With Consent of Securityholders. 

With the written consent of the holders of at least a majority in aggregate principal amount of the Securities of each series affected by
such supplemental indenture or indentures at the time Outstanding, the Company, when authorized by a Board Resolution, and the Trustee may from time to time and at any time enter into an indenture or indentures supplemental hereto (which shall
conform to the provisions of the Trust Indenture Act as then in effect) for the purpose of adding any provisions to or changing in any manner or eliminating any of the provisions of this Indenture or of any supplemental indenture or of modifying in
any manner not covered by Section 9.01 the rights of the holders of the Securities of such series under this Indenture; provided, however, that no such supplemental indenture shall, without the consent of the holders of each Security then
Outstanding and affected thereby, (a) extend the fixed maturity of any Securities of any series, (b) reduce the principal amount, reduce the rate of or extend the time of payment of interest, or reduce any premium payable upon the
redemption of any series of Securities or (b) reduce the percentage of Securities, the holders of which are required to consent to any amendment, supplement, modification or waiver. 

  
 39.

 It shall not be necessary for the consent of the Securityholders of any series affected
thereby under this Section to approve the particular form of any proposed supplemental indenture, but it shall be sufficient if such consent shall approve the substance thereof. 

Section 9.03 Effect of Supplemental Indentures. 
 Upon the execution of any supplemental indenture pursuant to the provisions of this Article or of Section 10.01, this Indenture shall, with respect to such series, be and be deemed to be modified and
amended in accordance therewith and the respective rights, limitations of rights, obligations, duties and immunities under this Indenture of the Trustee, the Company and the holders of Securities of the series affected thereby shall thereafter be
determined, exercised and enforced hereunder subject in all respects to such modifications and amendments, and all the terms and conditions of any such supplemental indenture shall be and be deemed to be part of the terms and conditions of this
Indenture for any and all purposes. 
 Section 9.04 Securities Affected by Supplemental Indentures. 

Securities of any series affected by a supplemental indenture, authenticated and delivered after the execution of such supplemental
indenture pursuant to the provisions of this Article or of Section 10.01, may bear a notation in form approved by the Company, provided such form meets the requirements of any securities exchange upon which such series may be listed, as to any
matter provided for in such supplemental indenture. If the Company shall so determine, new Securities of that series so modified as to conform, in the opinion of the Board of Directors, to any modification of this Indenture contained in any such
supplemental indenture may be prepared by the Company, authenticated by the Trustee and delivered in exchange for the Securities of that series then Outstanding. 
 Section 9.05 Execution of Supplemental Indentures. 
 Upon the request
of the Company, accompanied by its Board Resolutions authorizing the execution of any such supplemental indenture, and upon the filing with the Trustee of evidence of the consent of Securityholders required to consent thereto as aforesaid, the
Trustee shall join with the Company in the execution of such supplemental indenture unless such supplemental indenture affects the Trustee’s own rights, duties or immunities under this Indenture or otherwise, in which case the Trustee may in
its discretion but shall not be obligated to enter into such supplemental indenture. The Trustee, subject to the provisions of Sections 7.01 and 7.02, shall receive an Officer’s Certificate upon request and an Opinion of Counsel as conclusive
evidence that any supplemental indenture executed pursuant to this Article is authorized or permitted by the terms of this Article, that all conditions precedent to the execution of the supplemental indenture have been complied with and the
Supplemental Indenture is a valid and legally binding instrument enforceable against the Company. 
 Promptly after the
execution by the Company and the Trustee of any supplemental indenture pursuant to the provisions of this Section, the Company shall (or shall direct the Trustee to) transmit by mail, first class postage prepaid, a notice, setting forth in general
terms the substance of such supplemental indenture, to the Securityholders of all series affected thereby .as their names and addresses appear upon the Security Register. Any failure of the Company to mail, or cause the mailing of, such notice, or
any defect therein, shall not, however, in any way impair or affect the validity of any such supplemental indenture. 

  
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 ARTICLE 10 
 SUCCESSOR ENTITY 
 Section 10.01 Company May Consolidate, Etc.

 Nothing contained in this Indenture shall prevent any consolidation or merger of the Company with or into any other Person
(whether or not affiliated with the Company) or successive consolidations or mergers in which the Company or its successor or successors shall be a party or parties, or shall prevent any sale, conveyance, transfer or other disposition of the
property of the Company or its successor or successors as an entirety, or substantially as an entirety, to any other corporation (whether or not affiliated with the Company or its successor or successors) authorized to acquire and operate the same;
provided, however, (a) the Company hereby covenants and agrees that, upon any such consolidation or merger (in each case, if the Company is not the survivor of such transaction), sale, conveyance, transfer or other disposition, the due and
punctual payment of the principal of (premium, if any) and interest on all of the Securities of all series in accordance with the terms of each series, according to their tenor, and the due and punctual performance and observance of all the
covenants and conditions of this Indenture with respect to each series or established with respect to such series pursuant to Section 2.01 to be kept or performed by the Company shall be expressly assumed, by supplemental indenture (which shall
conform to the provisions of the Trust Indenture Act, as then in effect) reasonably satisfactory in form to the Trustee executed and delivered to the Trustee by the entity formed by such consolidation, or into which the Company shall have been
merged, or by the entity which shall have acquired such property and (b) in the event that the Securities of any series then Outstanding are convertible into or exchangeable for shares of common stock or other securities of the Company, such
entity shall, by such supplemental indenture, make provision so that the Securityholders of Securities of that series shall thereafter be entitled to receive upon conversion or exchange of such Securities the number of securities or property to
which a holder of the number of shares of common stock or other securities of the Company deliverable upon conversion or exchange of those Securities would have been entitled had such conversion or exchange occurred immediately prior to such
consolidation, merger, sale, conveyance, transfer or other disposition. 
 Section 10.02 Successor Entity
Substituted. 
 (a) In case of any such consolidation, merger, sale, conveyance, transfer or other disposition and
upon the assumption by the successor entity by supplemental indenture, executed and delivered to the Trustee and satisfactory in form to the Trustee, of the obligations set forth under Section 10.01 on all of the Securities of all series
Outstanding, such successor entity shall succeed to and be substituted for the Company with the same effect as if it had been named as the Company herein, and thereupon the predecessor corporation shall be relieved of all obligations and covenants
under this Indenture and the Securities. 

  
 41.

 (b) In case of any such consolidation, merger, sale, conveyance, transfer or other
disposition, such changes in phraseology and form (but not in substance) may be made in the Securities thereafter to be issued as may be appropriate. 
 (c) Nothing contained in this Article shall require any action by the Company in the case of a consolidation or merger of any Person into the Company where the Company is the survivor of such
transaction, or the acquisition by the Company, by purchase or otherwise, of all or any part of the property of any other Person (whether or not affiliated with the Company). 
 ARTICLE 11 
 SATISFACTION AND DISCHARGE 

Section 11.01 Satisfaction and Discharge of Indenture. 

If at any time: (a) the Company shall have delivered to the Trustee for cancellation all Securities of a series theretofore
authenticated and not delivered to the Trustee for cancellation (other than any Securities that shall have been destroyed, lost or stolen and that shall have been replaced or paid as provided in Section 2.07 and Securities for whose payment
money or Governmental Obligations have theretofore been deposited in trust or segregated and held in trust by the Company and thereupon repaid to the Company or discharged from such trust, as provided in Section 11.05); or (b) all such
Securities of a particular series not theretofore delivered to the Trustee for cancellation shall have become due and payable, or are by their terms to become due and payable within one year or are to be called for redemption within one year under
arrangements satisfactory to the Trustee for the giving of notice of redemption, and the Company shall deposit or cause to be deposited with the Trustee as trust funds the entire amount in moneys or Governmental Obligations or a combination thereof,
sufficient in the opinion of a nationally recognized firm of independent public accountants expressed in a written certification thereof delivered to the Trustee, to pay at maturity or upon redemption all Securities of that series not theretofore
delivered to the Trustee for cancellation, including principal (and premium, if any) and interest due or to become due to such date of maturity or date fixed for redemption, as the case may be, and if the Company shall also pay or cause to be paid
all other sums payable hereunder with respect to such series by the Company then this Indenture shall thereupon cease to be of further effect with respect to such series except for the provisions of Sections 2.03, 2.05, 2.07, 4.01, 4.02, 4.03 and
7.10, that shall survive until the date of maturity or redemption date, as the case may be, and Sections 7.06 and 11.05, that shall survive to such date and thereafter, and the Trustee, on demand of the Company and at the cost and expense of the
Company shall execute proper instruments acknowledging satisfaction of and discharging this Indenture with respect to such series. 
 Section 11.02 Discharge of Obligations. 
 If at any time all such
Securities of a particular series not heretofore delivered to the Trustee for cancellation or that have not become due and payable as described in Section 11.01 shall have been paid by the Company by depositing irrevocably with the Trustee as
trust funds moneys or an amount of Governmental Obligations sufficient to pay at maturity or upon redemption all such Securities of that series not theretofore delivered to the Trustee for 

  
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cancellation, including principal (and premium, if any) and interest due or to become due to such date of maturity or date fixed for redemption, as the case may be, and if the Company shall also
pay or cause to be paid all other sums payable hereunder by the Company with respect to such series, then after the date such moneys or Governmental Obligations, as the case may be, are deposited with the Trustee the obligations of the Company under
this Indenture with respect to such series shall cease to be of further effect except for the provisions of Sections 2.03, 2.05, 2.07, 4,01, 4.02, 4,03, 7.06, 7.10 and 11.05 hereof that shall survive until such Securities shall mature and be paid.

 Thereafter, Sections 7.06 and 11.05 shall survive. 
 Section 11.03 Deposited Moneys to be Held in Trust. 
 All moneys or
Governmental Obligations deposited with the Trustee pursuant to Sections 11.01 or 11.02 shall be held in trust and shall be available for payment as due, either directly or through any paying agent (including the Company acting as its own paying
agent), to the holders of the particular series of Securities for the payment or redemption of which such moneys or Governmental Obligations have been deposited with the Trustee. 

Section 11.04 Payment of Moneys Held by Paying Agents. 

In connection with the satisfaction and discharge of this Indenture all moneys or Governmental Obligations then held by any paying agent
under the provisions of this Indenture shall, upon demand of the Company, be paid to the Trustee and thereupon such paying agent shall be released from all further liability with respect to such moneys or Governmental Obligations. 

Section 11.05 Repayment to Company. 
 Any moneys or Governmental Obligations deposited with any paying agent or the Trustee, or then held by the Company, in trust for payment of principal of or premium, if any, or interest on the Securities
of a particular series that are not applied but remain unclaimed by the holders of such Securities for at least two years after the date upon which the principal of (and premium, if any) or interest on such Securities shall have respectively become
due and payable, or such other shorter period set forth in applicable escheat or abandoned or unclaimed property law, shall be repaid to the Company on May 31 of each year or upon the Company’s request or (if then held by the Company)
shall be discharged from such trust; and thereupon the paying agent and the Trustee shall be released from all further liability with respect to such moneys or Governmental Obligations, and the holder of any of the Securities entitled to receive
such payment shall thereafter, as a general creditor, look only to the Company for the payment thereof. 

  
 43.

 ARTICLE 12 
 IMMUNITY OF INCORPORATORS, STOCKHOLDERS, OFFICERS AND DIRECTORS 

Section 12.01 No Recourse. 
 No recourse under or upon any obligation, covenant or agreement of this Indenture, or of any Security, or for any claim based thereon or otherwise in respect thereof, shall be had against any
incorporator, stockholder, officer or director, past, present or future as such, of the Company or of any predecessor or successor corporation, either directly or through the Company or any such predecessor or successor corporation, whether by
virtue of any constitution, statute or rule of law, or by the enforcement of any assessment or penalty or otherwise; it being expressly understood that this Indenture and the obligations issued hereunder are solely corporate obligations, and that no
such personal liability whatever shall attach to, or is or shall be incurred by, the incorporators, stockholders, officers or directors as such, of the Company or of any predecessor or successor corporation, or any of them, because of the creation
of the indebtedness hereby authorized, or under or by reason of the obligations, covenants or agreements contained in this Indenture or in any of the Securities or implied therefrom; and that any and all such personal liability of every name and
nature, either at common law or in equity or by constitution or statute, of, and any and all such rights and claims against, every such incorporator, stockholder, officer or director as such, because of the creation of the indebtedness hereby
authorized, or under or by reason of the obligations, covenants or agreements contained in this Indenture or in any of the Securities or implied therefrom, are hereby expressly waived and released as a condition of, and as a consideration for, the
execution of this Indenture and the issuance of such Securities. 
 ARTICLE 13 

MISCELLANEOUS PROVISIONS 
 Section 13.01 Effect on Successors and Assigns. 
 All the covenants,
stipulations, promises and agreements in this Indenture made by or on behalf of the Company shall bind its successors and assigns, whether so expressed or not. 
 Section 13.02 Actions by Successor. 
 Any act or proceeding by any
provision of this Indenture authorized or required to be done or performed by any board, committee or officer of the Company shall and may be done and performed with like force and effect by the corresponding board, committee or officer of any
corporation that shall at the time be the lawful successor of the Company. 
 Section 13.03 Surrender of Company
Powers. 
 The Company by instrument in writing executed by authority of its Board of Directors and delivered to the Trustee
may surrender any of the powers reserved to the Company, and thereupon such power so surrendered shall terminate both as to the Company and as to any successor corporation. 

  
 44.

 Section 13.04 Notices. 

Except as otherwise expressly provided herein, any notice, request or demand that by any provision of this Indenture
is required or permitted to be given, made or served by the Trustee, the Security Registrar, any paying or other agent under this Indenture, the holders of Securities or any other Person pursuant to this Indenture to or on the Company, may be given
or served by being in writing and sent by electronic transmission or deposited in first class mail, postage prepaid, addressed (until another address is filed in writing by the Company with the Trustee), to the Company as follows: Medivation, Inc.,
201 Spear Street, 3rd Floor, San Francisco, California
94105, Attention: C. Patrick Machado. Any notice, election, request or demand by the Company or any Securityholder or by any other Person pursuant to this Indenture to or upon the Trustee shall be deemed to have been sufficiently given or made, for
all purposes, if given or made in writing at the Corporate Trust Office of the Trustee. 
 Section 13.05 Governing
Law. 
 This Indenture and each Security shall be deemed to be a contract made under the internal laws of the State of New
York, and for all purposes shall be construed in accordance with the laws of said State, except to the extent that the Trust Indenture Act is applicable. 
 In addition, the Company: (a) agrees that any suit, action or proceeding against it arising out of or relating to this Indenture or any Securities, as the case may be, may be instituted in any U.S.
federal court with applicable subject matter jurisdiction sitting in The City of New York; (b) waives, to the fullest extent permitted by applicable law, any objection which it may now or hereafter have to the laying of venue of any such suit,
action or proceeding, and any claim that any suit, action or proceeding in such a court has been brought in an inconvenient forum; and (c) submits to the non-exclusive jurisdiction of such courts in any suit, action or proceeding. 

Section 13.06 Treatment of Securities as Debt. 
 It is intended that the Securities will be treated as indebtedness and not as equity for federal income tax purposes. The provisions of this Indenture shall be interpreted to further this intention.

 Section 13.07 Certificates as to Conditions Precedent. 

(a) Upon any application or demand by the Company to the Trustee to take any action under any of the provisions of this Indenture
(except with respect to the initial issuance of Securities), the Company shall furnish to the Trustee an Officer’s Certificate and an Opinion of Counsel or reliance letter, upon request, stating that all conditions precedent provided for in
this Indenture (other than the certificate to be delivered pursuant to Section 13.12 or Section 314(a)(4) of the Trust Indenture Act) relating to the proposed action have been complied with, except that in the case of any such application
or demand as to which the furnishing of such documents is specifically required by any provision of this Indenture relating to such particular 

  
 45.

 
application or demand, no additional certificate need be furnished; provided, however, that no Opinion of Counsel or reliance letter shall be required in connection with the issuance of
Securities on the date on which the Securities are originally issued or deemed issued as set forth on the face of such Securities. 
 (b) Each certificate or opinion provided for in this Indenture and delivered to the Trustee with respect to compliance with a condition or covenant in this Indenture (other than the certificate to
be delivered pursuant to Section 13.12 or Section 314(a)(4) of the Trust Indenture Act) shall include (i) a statement that the Person making such certificate or opinion has read such covenant or condition; (ii) a brief statement
as to the nature and scope of the examination or investigation upon which the statements contained in such certificate or opinion are based; (iii) a statement that, in the opinion of such Person, he has made such examination or investigation as
is reasonably necessary to enable him to express an informed opinion as to whether or not such covenant or condition has been complied with; and (iv) a statement as to whether or not, in the opinion of such Person, such condition or covenant
has been complied with. 
 Section 13.08 Payments on Business Days. 

Except as provided pursuant to Section 2.01 pursuant to a Board Resolution, and set forth in an Officer’s Certificate,
established in one or more indentures supplemental to this Indenture, or otherwise explicitly stated, in any case where the date of maturity of interest or principal of any Security, or the date for the repurchase of any Security or for the
redemption of any Security shall not be a Business Day, then payment of interest, principal (and premium, if any), redemption price or repurchase price due on such date may be made on the next succeeding Business Day with the same force and effect
as if made on the nominal date of maturity, repurchase or redemption, and no interest shall accrue for the period after such nominal date as a result of such delay. 
 Section 13.09 Conflict with Trust Indenture Act. 
 If and to the extent
that any provision of this Indenture limits, qualifies or conflicts with the duties imposed by Sections 310 to 317, inclusive, of the Trust Indenture Act, such imposed duties shall control. 

Section 13.10 Counterparts. 
 This Indenture may be executed in any number of counterparts, each of which shall be an original, but such counterparts shall together constitute but one and the same instrument. 

Section 13.11 Separability. 
 In case any one or more of the provisions contained in this Indenture or in the Securities of any series shall for any reason be held to be invalid, illegal or unenforceable in any respect, such
invalidity, illegality or unenforceability shall not affect any other provisions of this Indenture or of such Securities, but this Indenture and such Securities shall be construed as if such invalid or illegal or unenforceable provision had never
been contained herein or therein. 

  
 46.

 Section 13.12 Compliance Certificates. 

The Company shall deliver to the Trustee, within 120 days after the end of each fiscal year during which any Securities of any series were
outstanding, an officer’s certificate stating whether or not the signers know of any Event of Default that occurred during such fiscal year. Such certificate shall contain a certification from the principal executive officer, principal
financial officer or principal accounting officer of the Company that a review has been conducted of the activities of the Company and the Company’s performance under this Indenture and that the Company has complied with all conditions and
covenants under this Indenture. For purposes of this Section 13.12, such compliance shall be determined without regard to any period of grace or requirement of notice provided under this Indenture. If the officer of the Company signing such
certificate has knowledge of such an Event of Default, the certificate shall describe any such Event of Default and its status. 

Section 13.13 U.S.A Patriot Act. 
 The parties hereto acknowledge that in accordance with Section 326 of the U.S.A. Patriot Act, the Trustee, like all financial institutions and in order to help fight the funding of terrorism and
money laundering, is required to obtain, verify, and record information that identifies each person or legal entity that establishes a relationship or opens an account with the Trustee. The parties to this Indenture agree that they will provide the
Trustee with such information as it may request in order for the Trustee to satisfy the requirements of the U.S.A. Patriot Act. 

Section 13.14 Force Majeure. 
 In no event shall the Trustee, the Security Registrar, any paying agent or any other agent under this Indenture be responsible or liable for any failure or delay in the performance of its obligations
hereunder arising out of or caused by, directly or indirectly, forces beyond its control, including without limitation, strikes, work stoppages, accidents, acts of war or terrorism, civil or military disturbances, nuclear or natural catastrophes or
acts of God, and interruptions, loss or malfunctions or utilities, communications or computer (software and hardware) services; it being understood that the Trustee, the Security Registrar, any paying agent or any other agent under this Indenture
shall use reasonable efforts which are consistent with accepted practices in the banking industry to resume performance as soon as practicable under the circumstances. 
 Section 13.15 Table of Contents; Headings. 
 The table of contents and
headings of the articles and sections of this Indenture have been inserted for convenience of reference only, are not intended to be considered a part hereof, and will not modify or restrict any of the terms or provisions hereof. 

  
 47.

 IN WITNESS WHEREOF, the parties hereto
have caused this Indenture to be duly executed all as of the day and year first above written. 
  

			
	MEDIVATION, INC.
		
	By:	 	 /s/ C. Patrick Machado

	Name:	 	C. Patrick Machado
	Title:	 	Chief Business Officer and Chief Financial Officer
	
	WELLS FARGO BANK, NATIONAL ASSOCIATION, as Trustee
		
	By:	 	 /s/ Michael Tu

	Name:	 	Michael Tu
	Title:	 	Assistant Vice President

  
 48.

 CROSS-REFERENCE TABLE (1) 

 

			
	 Section of Trust Indenture Act of 1939, as Amended
	  	 Section of Indenture

	 310(a)
	  	7.09
	 310(b)
	  	7.08
		  	7.10
	 310(c)
	  	Inapplicable
	 311(a)
	  	7.13
	 311(b)
	  	7.13
	 311(c)
	  	Inapplicable
	 312(a)
	  	5.01
		  	5.02(a)
	 312(b)
	  	5.02(c)
	 312(c)
	  	5.02(c)
	 313(a)
	  	5.04(a)
	 313(b)
	  	5.04(b)
	 313(c)
	  	5.04(a)
		  	5.04(b)
	 313(d)
	  	5.04(c)
	 314(a)
	  	5.03
		  	13.12
	 314(b)
	  	Inapplicable
	 314(c)
	  	13.07(a)
	 314(d)
	  	Inapplicable
	 314(e)
	  	13.07(b)
	 314(f)
	  	Inapplicable
	 315(a)
	  	7.01(a)
		  	7.01(b)
	 315(b)
	  	7.14
	 315(c)
	  	7.01
	 315(d)
	  	7.01(b)
	 315(e)
	  	6.07
	 316(a)
	  	6.06
		  	8.04
	 316(b)
	  	6.04
	 316(c)
	  	8.01
	 317(a)
	  	6.02
	 317(b)
	  	4.03
	 318(a)
	  	13.09

  

	(1)	This Cross-Reference Table does not constitute part of the Indenture and shall not have any bearing on the interpretation of any of its terms or provisions.

  
 49.First Supplemental Indenture, Dated March 19, 2012

 Exhibit 4.2 
 Execution Version 
  

 
 MEDIVATION, INC. 

as Issuer 
 AND

 WELLS FARGO BANK, NATIONAL ASSOCIATION 
 as Trustee 
  

 
 First
Supplemental Indenture 
 Dated as of March 19, 2012 

to Indenture 

Dated as of March 19, 2012 
  

 
 2.625%
Convertible Senior Notes due 2017 
  
  

 TABLE OF CONTENTS 

 

							
	 	  	 	  	Page	 
		  	ARTICLE 1	  			
		  	DEFINITIONS AND OTHER PROVISIONS OF GENERAL
APPLICATION	  			
			
	Section 1.01.	  	Scope of Supplemental Indenture	  	 	2	  
	Section 1.02.	  	Definitions	  	 	2	  
	Section 1.03.	  	Section References	  	 	11	  
			
		  	ARTICLE 2	  			
		  	THE NOTES	  			
			
	Section 2.01.	  	Designation, Amount and Issuance of Notes	  	 	11	  
	Section 2.02.	  	Form of the Notes	  	 	11	  
	Section 2.03.	  	Date and Denomination of Notes; Payment at the Stated Maturity Date; Payment of Interest	  	 	12	  
	Section 2.04.	  	Security Registrar, Paying Agent and Conversion Agent	  	 	12	  
	Section 2.05.	  	Registration of Transfer and Exchange	  	 	13	  
	Section 2.06.	  	Global Securities	  	 	13	  
	Section 2.07.	  	Purchase and Cancellation	  	 	14	  
	Section 2.08.	  	Additional Notes	  	 	15	  
	Section 2.09.	  	Mutilated, Destroyed, Lost or Stolen Notes	  	 	15	  
			
		  	ARTICLE 3	  			
		  	PARTICULAR COVENANTS OF THE COMPANY	  			
			
	Section 3.01.	  	Covenants in Original Indenture	  	 	15	  
	Section 3.02.	  	Book-Entry System	  	 	15	  
	Section 3.03.	  	Compliance Certificate	  	 	15	  
	Section 3.04.	  	Further Instruments and Acts	  	 	15	  
			
		  	ARTICLE 4	  			
		  	REPURCHASE OF NOTES	  			
			
	Section 4.01.	  	Right To Require Repurchase Upon a Fundamental Change	  	 	16	  
			
		  	ARTICLE 5	  			
		  	CONVERSION	  			
			
	Section 5.01.	  	Conversion Privilege and Conversion Rate	  	 	19	  
	Section 5.02.	  	Conversion Rate Adjustment Upon Certain Make-Whole Adjustment Events	  	 	22	  
	Section 5.03.	  	Exercise of Conversion Privilege	  	 	23	  
	Section 5.04.	  	Settlement of Conversion Obligation	  	 	24	  
	Section 5.05.	  	Fractions of Shares	  	 	26	  

  
 i 

							
	Section 5.06.	  	Adjustment of Conversion Rate	  	 	27	  
	Section 5.07.	  	Notice of Adjustments of Conversion Rate	  	 	35	  
	Section 5.08.	  	Company To Reserve Common Stock	  	 	35	  
	Section 5.09.	  	Taxes on Conversions	  	 	35	  
	Section 5.10.	  	Certain Covenants	  	 	36	  
	Section 5.11.	  	Cancellation of Converted Notes	  	 	36	  
	Section 5.12.	  	Provision in Case of Effect of Reclassification, Consolidation, Merger or Sale	  	 	36	  
	Section 5.13.	  	Responsibility of Trustee for Conversion Provisions	  	 	37	  
	Section 5.14.	  	Notice to Holders Prior to Certain Actions	  	 	38	  
	Section 5.15.	  	Stockholder Rights Plan	  	 	38	  
			
		  	ARTICLE 6	  			
		  	REDEMPTION	  			
			
	Section 6.01.	  	Original Indenture	  	 	38	  
	Section 6.02.	  	Redemption	  	 	39	  
	Section 6.03.	  	Notice of Optional Redemption; Selection of Notes	  	 	39	  
	Section 6.04.	  	Payment of Notes Called for Redemption	  	 	40	  
	Section 6.05.	  	Restrictions on Redemption	  	 	41	  
			
		  	ARTICLE 7	  			
		  	EVENTS OF DEFAULT; REMEDIES	  			
			
	Section 7.01.	  	Original Indenture	  	 	41	  
	Section 7.02.	  	Events of Default.	  	 	41	  
	Section 7.03.	  	Acceleration of Maturity; Rescission and Annulment	  	 	43	  
	Section 7.04.	  	Limitation on Suits	  	 	44	  
	Section 7.05.	  	Unconditional Right of Holders To Receive Payment	  	 	44	  
	Section 7.06.	  	Waiver of Defaults and Events of Default	  	 	44	  
	Section 7.07.	  	Undertaking for Costs	  	 	45	  
	Section 7.08.	  	Waiver of Stay or Extension Laws	  	 	45	  
			
		  	ARTICLE 8	  			
		  	CONSOLIDATION, MERGER, CONVEYANCE, TRANSFER OR LEASE	  			
			
	Section 8.01.	  	Original Indenture	  	 	45	  
	Section 8.02.	  	Consolidation, Merger and Sale of Assets	  	 	46	  
	Section 8.03.	  	Successor Substituted	  	 	46	  
			
		  	ARTICLE 9	  			
		  	REPORTS BY COMPANY	  			
			
	Section 9.01.	  	Reports by Company	  	 	46	  

  
 ii 

							
	 	  	ARTICLE 10	  	 	 
		  	SATISFACTION AND DISCHARGE	  			
	 Section 10.01.
	  	Original Indenture	  	 	47	  
	 Section 10.02.
	  	Discharge of Indenture	  	 	47	  
	 Section 10.03.
	  	Deposited Monies and Shares To Be Held in Trust by Trustee	  	 	47	  
	 Section 10.04.
	  	Paying Agent or Conversion Agent To Repay Monies and Shares Held	  	 	48	  
	 Section 10.05.
	  	Reinstatement	  	 	48	  
			
		  	ARTICLE 11	  			
		  	SUPPLEMENTAL INDENTURES	  			
			
	 Section 11.01.
	  	Supplemental Indentures Without Consent of Holders	  	 	49	  
	 Section 11.02.
	  	Supplemental Indentures with Consent of Holders	  	 	49	  
			
	 	  	ARTICLE 12	  	 	 
		  	MISCELLANEOUS	  			
			
	 Section 12.01.
	  	Provisions of Original Indenture	  	 	50	  
	 Section 12.02.
	  	Successors	  	 	50	  
	 Section 12.03.
	  	Multiple Originals	  	 	50	  
	 Section 12.04.
	  	Calculations	  	 	51	  
	 Section 12.05.
	  	Benefits of Supplemental Indenture	  	 	51	  
	 Section 12.06.
	  	Waiver of Jury Trial	  	 	51	  
	 Section 12.07.
	  	Governing Law	  	 	51	  
			
	 Schedule A
	  	Make-Whole Table	  			
			
		  	EXHIBITS	  			
	 Exhibit A –
	  	Form of Security	  			

  
 iii

 FIRST SUPPLEMENTAL INDENTURE, dated as of March 19, 2012, between
Medivation, Inc., a corporation duly organized and existing under the laws of the State of Delaware, as issuer (the “Company”), having its principal office at 201 Spear Street, 3rd Floor, San Francisco, California 94105, and Wells Fargo Bank,
National Association, a national banking association, as trustee (the “Trustee”) to the Indenture dated as of March 19, 2012, between the Company and the Trustee (the “Original Indenture”; the Original
Indenture as amended and supplemented hereby and as it may be further amended and supplemented in accordance herewith and therewith, with respect to the Notes, the “Indenture”). 

RECITALS OF THE COMPANY 
 WHEREAS, the Company executed and delivered the Original Indenture to the Trustee to provide for, among other things, the issuance, from time to time, of the Company’s Securities, in an unlimited
aggregate principal amount, in one or more series to be established by the Company under, and authenticated and delivered as provided in, the Original Indenture; 
 WHEREAS, Section 2.01 of the Original Indenture provides for the Company to establish Securities of any series pursuant to a supplemental indenture, and Section 9.01(g) of the Original Indenture
provides for the Company and the Trustee to enter into any such supplemental indenture to provide for the issuance of and establish the form and terms and conditions of Securities of any series as permitted by the Original Indenture; 

WHEREAS, the Board of Directors has duly adopted resolutions authorizing the Company to execute and deliver this Supplemental Indenture;

 WHEREAS, pursuant to the terms of the Original Indenture, the Company desires to provide for the establishment of a new
series of its Securities to be known as its “2.625% Convertible Senior Notes due 2017” (each, a “Note” and, collectively, the “Notes”) the form and substance of the Notes and the terms, provisions and
conditions thereof to be set forth as provided in the Original Indenture and this Supplemental Indenture; and 
 WHEREAS, all
things necessary to make the Notes, when executed by the Company and authenticated and delivered hereunder and duly issued by the Company, the valid and legally binding obligations of the Company, and to make this Supplemental Indenture a valid and
legally binding agreement of the Company, in accordance with the terms of the Notes and this Supplemental Indenture, have been done; 

 NOW, THEREFORE, THIS SUPPLEMENTAL INDENTURE WITNESSETH, for and in consideration of the
premises and the purchases of the Notes by the Holders thereof, it is mutually agreed, for the benefit of the Company and the equal and proportionate benefit of all Holders of the Notes, as follows: 

ARTICLE 1 

DEFINITIONS AND OTHER PROVISIONS OF GENERAL
APPLICATION 
 Section 1.01. Scope of Supplemental Indenture. The changes, modifications and
supplements to the Original Indenture effected by this Supplemental Indenture shall be applicable only with respect to, and shall only govern the terms of, the Notes, and shall not apply to any other Securities that may be issued under the Original
Indenture unless a supplemental indenture with respect to such other Securities specifically incorporates such changes, modifications and supplements. With respect to the Notes, the provisions of this Supplemental Indenture shall supplement and, to
the extent they are inconsistent therewith, supersede any corresponding provisions in the Original Indenture. 

Section 1.02. Definitions. For all purposes of the Indenture, except as otherwise expressly provided or unless the context
otherwise requires: 
 (i) the terms defined in this Article 1 have the meanings assigned to them in this Article
and include the plural as well as the singular; 
 (ii) all words, terms and phrases used in this Supplemental
Indenture and defined in the Original Indenture (but not otherwise defined herein) shall have the same meanings as in the Original Indenture; 
 (iii) all other terms used herein that are defined in the Trust Indenture Act, either directly or by reference therein, have the meanings assigned to them therein; 

(iv) all accounting terms not otherwise defined herein have the meanings assigned to them in accordance with GAAP; and

 (v) the words “herein,” “hereof” and “hereunder” and other words of similar
import refer to this Supplemental Indenture as a whole and not to any particular Article, Section or other subdivision. 

“Additional Interest” has the meaning specified in Section 7.03. 

“Additional Notes” has the meaning specified in Section 2.08. 

“Additional Shares” has the meaning specified in Section 5.02(a). 

“Bid Solicitation Agent” means, initially, the Trustee, or any agent the Company may appoint in the future (which may be
the Company) to determine a Trading Price for the Notes as may be required pursuant to Section 5.01(a)(ii). 

  
 2 

 “Business Day” means any day, other than (x) a Saturday, (y) a
Sunday or (z) a day on which state or federally chartered banking institutions in New York, New York are not required to be open. 
 “Capital Stock” means any and all shares, interests, participations, rights or other equivalents (however designated) of corporate stock and limited liability company interests and, with
respect to partnerships, partnership interests (whether general or limited) and any other interest or participation that confers on a Person the right to receive a share of the profits and losses of, or distributions of assets of, such partnership.

 A “Change in Control” will be deemed to have occurred if any of the following occurs after the Issue Date:

 (1) any “person” or “group” within the meaning of Section 13(d) under the Exchange Act, other than
the Company, its Subsidiaries and employee benefit plans of the Company or its Subsidiaries, files a Schedule TO or any schedule, form or report under the Exchange Act disclosing, or the Company otherwise becomes aware, that such person or group
has, or becomes the direct or indirect “beneficial owner,” as defined in Rule 13d-3 under the Exchange Act, of, shares of the Company’s voting stock representing 50% or more of the total voting power of all outstanding classes of the
Company’s voting stock entitled to vote generally in elections of directors; 
 (2) the consummation of (A) any
recapitalization, reclassification or change of Common Stock (other than changes resulting from a subdivision or combination) as a result of which the Common Stock would be converted into, or exchanged for, stock, other securities, other property or
assets; (B) any share exchange, consolidation or merger of the Company pursuant to which the Common Stock will be converted into cash, securities or other property; or (C) any sale, lease or other transfer in one transaction or a series of
transactions of all or substantially all of the consolidated assets of the Company and its Subsidiaries, taken as a whole, to any Person other than one of the Company’s Subsidiaries; provided that a transaction described in clause
(A) or (B) above pursuant to which the persons that “beneficially owned,” directly or indirectly, the shares of the Company’s voting stock immediately prior to such transaction “beneficially own,” directly or
indirectly, shares of the Company’s voting stock representing at least a majority of the total voting power of all outstanding classes of voting stock of the surviving Person and such holders’ proportional voting power immediately after
such transaction vis-à-vis each other with respect to the securities they receive in such transaction will be in substantially the same proportions as their respective voting power vis-à-vis each other immediately prior to such
transaction shall not constitute a “Change in Control”; or 
 (3) the holders of the Company’s Capital Stock
approve any plan or proposal for the liquidation or dissolution of the Company (whether or not otherwise in compliance with the Indenture). 
 Notwithstanding the foregoing, a transaction or series of related transactions described in clause (1) or (2) of the definition of “Change in Control” shall not constitute a Change in
Control if at least 90% of the consideration paid for Common Stock in such transaction or transactions, 

  
 3 

 
excluding cash payments for any fractional share and cash payments made pursuant to dissenters’ appraisal rights, consists of shares of common stock (or American Depositary Receipts
representing common stock) traded on The New York Stock Exchange, The NASDAQ Global Select Market or The NASDAQ Global Market (or any of their respective successors), or will be so traded immediately following such transaction or transactions, and,
as a result therefrom, such consideration becomes the Reference Property for the Notes pursuant to Section 5.12 or any supplemental indenture executed pursuant to such Section. 

“close of business” means 5:00 p.m., New York City time. 

“Closing Sale Price” of the Common Stock on any date means the closing per share sale price (or, if no closing sale
price is reported, the average of the bid and ask prices or, if more than one in either case, the average of the average bid and the average ask prices) at 4:00 p.m. (New York City time) on such date as reported in composite transactions for
The NASDAQ Global Market or, if the Common Stock is not listed on The NASDAQ Global Market, the principal U.S. national or regional securities exchange on which the Common Stock is listed for trading or, if the Common Stock is not listed on a
U.S. national or regional securities exchange, as reported by OTC Markets Group Inc. at 4:00 p.m. (New York City time) on such date (or in either case the then-standard closing time for regular trading on the relevant exchange or trading
system); provided that if the Closing Sale Price of the Common Stock is not so reported, the “Closing Sale Price” shall be the average of the mid-point of the last bid and ask prices for the Common Stock on the relevant date from
each of at least three nationally recognized independent investment banking firms selected by the Company for this purpose. 

“Common Stock” means the shares of common stock, par value $0.01 per share, of the Company as they exist on the Issue
Date, subject to Section 5.12. 
 “Company” means the Person named as the “Company” in the first
paragraph of this instrument until a successor Person shall have become such pursuant to the applicable provisions of the Indenture, and thereafter “Company” shall mean such successor Person. 

“Conversion Agent” has the meaning specified in Section 2.04. 

“Conversion Date” has the meaning specified in Section 5.03(a). 

“Conversion Notice” has the meaning specified in Section 5.03(a). 

“Conversion Obligation” means, with respect to any conversion of a Note, the amount of cash, if any, and number of
shares of Common Stock, if any, that the Company is required to pay or deliver, as the case may be, upon such conversion. 

“Conversion Period” means, with respect to any conversion of a Note: 

(i) if the relevant Conversion Date occurs prior to the Final Settlement Method Election Date and does not occur during a Redemption
Period, the 20 consecutive Trading Day period beginning on, and including, the third Trading Day immediately following the related Conversion Date; 

  
 4 

 (ii) if the relevant Conversion Date occurs during a Redemption Period
(regardless of whether such Conversion Date is before or after the Final Settlement Method Election Date), the 20 consecutive Trading Day period beginning on, and including, the 22nd Scheduled Trading Day immediately preceding such Redemption Date; and 

(iii) if the relevant Conversion Date occurs on or after the Final Settlement Method Election Date and does not occur during a Redemption
Period, the 20 consecutive Trading Day period beginning on, and including, the 22nd Scheduled Trading Day immediately preceding the Stated Maturity Date. 
 “Conversion Price” means, in respect of each Note, as of any date $1,000 divided by the Conversion Rate as of such date. 

“Conversion Rate” means, initially 9.7586 shares of Common Stock per $1,000 principal amount of Notes, subject to
adjustment as set forth herein. 
 “custodian” means the Trustee, as custodian with respect to the Global
Securities, or any successor entity. 
 “Daily Conversion Value” means, for each Trading Day during the
Conversion Period, one-twentieth (1/20th) of the product of (i) the Conversion Rate on such Trading Day and (ii) the Daily VWAP of the Common Stock on such Trading Day. 

“Daily Measurement Value” means the Specified Dollar Amount in respect of a conversion divided by 20. 

“Daily Net Share Number” means, for each Trading Day during the relevant Conversion Period, a number of shares of Common
Stock equal to: 
 (1) the difference between the Daily Conversion Value for such Trading Day and the Daily Measurement Value,
divided by 
 (2) the Daily VWAP of the Common Stock for such Trading Day. 

“Daily Settlement Amount” for each $1,000 aggregate principal amount of Notes validly surrendered for conversion, and
for each Trading Day during the relevant Conversion Period, shall consist of: 
 (1) if (x) the Daily Conversion Value for
such Trading Day exceeds (y) the Daily Measurement Value, the sum of: 
 (a) a cash payment equal to the Daily Measurement
Value, and 
 (b) the Daily Net Share Number; or 

  
 5 

 (2) if the Daily Conversion Value for such Trading Day is less than or equal to the Daily
Measurement Value, a cash payment equal to the Daily Conversion Value. 
 “Daily VWAP” of the Common Stock (or
any security that is part of the Reference Property underlying the Notes, if applicable), in respect of any Trading Day, means the per share volume-weighted average price of Common Stock (or other security) as displayed under the heading
“Bloomberg VWAP” on Bloomberg Page MDVN Equity AQR (or its equivalent successor if such page is not available, or the Bloomberg Page for any security that is part of such Reference Property, if applicable) in respect of the period
from the scheduled open of trading until the scheduled close of trading of the primary trading session on such Trading Day or, if such volume-weighted average price is unavailable (or such Reference Property is not a security), the market value of
one share of Common Stock (or such Reference Property) on such Trading Day as determined in good faith by the Board of Directors in a commercially reasonable manner, using, if practicable, a volume-weighted average price method (unless such
Reference Property is not a security). The Daily VWAP will be determined without regard to after-hours trading or any other trading outside the regular trading session. 
 “Default” means any event that is or with the passage of time or the giving of notice or both would become an Event of Default. 

“Depositary” has the meaning set forth in the Original Indenture, which shall initially be The Depository Trust Company
until a successor Depositary shall have become such pursuant to the applicable provisions of the Indenture, and thereafter “Depositary” shall mean such successor Depositary. 

“Effective Date” has the meaning specified in Section 5.02(b). 

“Event of Default” has the meaning specified in Section 7.02. 

“Ex-Dividend Date” means the first date on which the shares of the Common Stock trade on the applicable exchange or in
the applicable market, regular way, without the right to receive the issuance, dividend or distribution in question, from the Company or, if applicable, from the seller of Common Stock on such exchange or market (in the form of due bills or
otherwise) as determined by such exchange or market. 
 “Exchange Act” means the U.S. Securities Exchange Act
of 1934, as amended. 
 “Expiration Date” has the meaning specified in Section 5.06(e). 

“Expiration Time” has the meaning specified in Section 5.06(e). 

“Final Settlement Method Election Date” means the 25th Scheduled Trading Day immediately preceding the Stated Maturity
Date. 
 “Free Convertibility Date” means January 1, 2017. 

  
 6 

 “Fundamental Change” means the occurrence of a Change in Control or a
Termination of Trading. 
 “Fundamental Change Expiration Time” has the meaning specified in
Section 4.01(a)(i). 
 “Fundamental Change Purchase Date” has the meaning specified in
Section 4.01(a). 
 “Fundamental Change Purchase Notice” has the meaning specified in
Section 4.01(a)(i). 
 “Fundamental Change Purchase Price” has the meaning specified in
Section 4.01(a). 
 “Fundamental Change Purchase Right Notice” has the meaning specified in
Section 4.01(b). 
 “GAAP” means generally accepted accounting principles set forth in the opinions and
pronouncements of the Accounting Principles Board of the American Institute of Certified Public Accountants and statements and pronouncements of the Financial Accounting Standards Board or in such other statements by such other entity as have been
approved by a significant segment of the accounting profession, in each case, as in effect in the United States from time to time. 
 “Indenture” has the meaning specified in the first paragraph of this Supplemental Indenture. 
 “Interest” means, when used with reference to the Notes, any interest payable under the terms of the Notes and the Additional Interest, if any. 

“Interest Payment Date” means each April 1 and October 1 of each year, or if any such day is not a Business
Day, the immediately following Business Day, commencing with October 1, 2012. 
 “Irrevocable Election”
has the meaning specified in Section 5.04(a)(iii). 
 “Issue Date” means March 19, 2012. 

“Make-Whole Adjustment Event” is (i) any Change of Control set forth in clause (1) or (2) of the
definition thereof (determined after giving effect to any exceptions or exclusions from such definition but without giving effect to the proviso in clause (2) of the definition thereof) and (ii) any Termination of Trading. 

“Market Disruption Event” means (i) a failure by The NASDAQ Global Market, or if the Common Stock is not listed on
The NASDAQ Global Market, the principal other U.S. national or regional securities exchange on which the Common Stock is then listed, to open for trading during its regular trading session or (ii) the occurrence or existence for more than one
half-hour period in the aggregate on any Scheduled Trading Day for the Common Stock of any suspension or limitation imposed on trading (by reason of movements in price exceeding limits 

  
 7 

 
permitted by The NASDAQ Global Market or otherwise) in the Common Stock or in any options contracts or future contracts relating to the Common Stock, and such suspension or limitation occurs or
exists at any time before 1:00 p.m. (New York City time) on such day. 
 “Maximum Conversion Rate” has the
meaning specified in Section 5.02(b). 
 “Merger Transaction” has the meaning specified in
Section 8.02. 
 “Note” or “Notes” has the meaning specified in the third paragraph of
the Recitals of the Company. 
 “open of business” means 9:00 a.m., New York City time. 

“Optional Redemption” has the meaning specified in Section 6.02. 

“Original Indenture” has the meaning specified in the first paragraph of this Supplemental Indenture. 

“Outstanding,” has the meaning specified in the Original Indenture except that, with respect to the Notes, (i) any
Notes converted pursuant to Article 5 and required to be cancelled shall cease to be Outstanding, (ii) if the Trustee or Paying Agent segregates and holds in trust, in accordance with the Indenture, on a Fundamental Change Purchase Date,
Redemption Date or Stated Maturity Date, money sufficient to pay all principal and Interest payable on that date with respect to the Notes (or portions thereof) to be purchased by the Company, redeemed or maturing, as the case may be, and the
Trustee or Paying Agent is not prohibited from paying such money to the Holders thereof on that date pursuant to the terms of the Indenture, then on and after that date such Notes (or portions thereof) shall cease to be Outstanding,
(iii) clause (b) of the definition of “Outstanding” in the Original Indenture shall not apply and (iv) any Notes purchased by the Company in accordance with Section 2.07 (other than Notes purchased pursuant to
cash-settled swaps or other derivatives) shall cease to be Outstanding. 
 “Paying Agent” means the
“paying agent” (within the meaning of the Original Indenture) with respect to the Notes, which shall initially be the Trustee. 
 “Physical Securities” means permanent certificated Notes in registered form issued in denominations of $1,000 principal amount and integral multiples thereof. 

“Place of Payment” has the meaning specified in Section 2.04. 

“Qualifying Bid” has the meaning specified in the definition of “Trading Price.” 

“Record Date” means, with respect to the payment of Interest, the March 15 (whether or not a Business Day)
immediately preceding an Interest Payment Date on April 1 and September 15 (whether or not a Business Day) immediately preceding an Interest Payment Date on October 1. 

“Redemption Date” has the meaning specified in Section 6.03. 

  
 8 

 “Redemption Notice” has the meaning specified in Section 6.03.

 “Redemption Period” means the period after the Company (or the Trustee on its behalf) has delivered a
Redemption Notice pursuant to Section 6.03 and prior to the close of business on the second Business Day preceding the related Redemption Date. 
 “Redemption Price” has the meaning specified in Section 6.02. 
 “Reference Property” has the meaning specified in Section 5.12. 
 “Relevant Distribution” has the meaning specified in Section 5.06(c). 
 “Scheduled Trading Day” means (i) a day that is scheduled to be a Trading Day on the principal U.S. national or regional securities exchange or market on which the Common Stock is
listed for trading or (ii) if the Common Stock is not listed on any such securities exchange or market, a Business Day. 

“SEC” means the U.S. Securities and Exchange Commission (or any successor thereto). 

“Securities Act” means the U.S. Securities Act of 1933, as amended, and the rules and regulations of the Commission
promulgated thereunder. 
 “Security Registrar” has the meaning specified in the Original Indenture, which,
with respect to the Notes, shall initially be the Trustee. 
 “Settlement Amount” has the meaning specified in
Section 5.04(a)(iv). 
 “Settlement Method” means the election of the Company as set forth in this
Supplemental Indenture of settling each Settlement Amount (i) solely in cash, (ii) in shares of Common Stock (plus cash in lieu of fractional shares) or (iii) in a combination of cash and shares of Common Stock with a particular
Specified Dollar Amount. 
 “Share Exchange Transaction” has the meaning specified in Section 5.12.

 “Significant Subsidiary” means a Subsidiary that is a “significant subsidiary” (as defined under
Rule 1-02(w) of Regulation S-X under the Exchange Act); provided that, in the case of a Subsidiary that meets the criteria of clause (3) of the definition thereof but not clause (1) or (2) thereof, such Subsidiary shall
not be deemed to be a Significant Subsidiary unless the Subsidiary’s income from continuing operations before income taxes, extraordinary items and cumulative effect of a change in accounting principle exclusive of amounts attributable to
any non-controlling interests for the last completed fiscal year prior to the date of such determination exceeds $25 million. 

“Specified Dollar Amount” means the maximum cash amount per $1,000 principal amount of Notes to be received upon
conversion as elected by the Company in the notice regarding the Company’s chosen Settlement Method (or deemed elected pursuant to Section 5.04(a)). 

  
 9 

 “Spin-Off” has the meaning specified in Section 5.06(c). 

“Stated Maturity Date” means April 1, 2017. 

“Stock Price” means, with respect to a Make-Whole Adjustment Event, (i) in the case of a Make-Whole Adjustment
Event described in clause (2) of the definition of Change in Control in which the Common Stock is acquired solely for cash, the price paid or deemed to be paid per share of Common Stock in the Change in Control, or (ii) in the case of any
other Make-Whole Adjustment Event, the average of the Closing Sale Prices of Common Stock over the five Trading Day period ending on the Trading Day immediately preceding the Effective Date of such other Make-Whole Adjustment Event. 

“Subsidiary” means a Person more than 50% of the outstanding voting stock or other voting interests of which is owned,
directly or indirectly, by the Company or by one or more other Subsidiaries, or by the Company and one or more other Subsidiaries. For the purposes of this definition, “voting stock or other voting interests” means stock or other voting
interests which ordinarily have voting power for the election of directors or comparable governing body, whether at all times or only so long as no senior class of stock or other interests has such voting power by reason of any contingency.

 “Supplemental Indenture” means this instrument, as it may from time to time be supplemented or amended by
one or more indentures supplemental hereto entered into pursuant to the applicable provisions hereof. 
 “Termination of
Trading” means the Common Stock (or other common stock or American Depositary Receipts representing common stock that constitutes Reference Property for the Notes) ceases to be listed or quoted on any of the New York Stock Exchange, The
NASDAQ Global Select Market or The NASDAQ Global Market (or any of their respective successors). 
 “Trading
Day” means (a) except for purposes of determining Settlement Amounts pursuant to Section 5.04, a day on which (i) The NASDAQ Global Market or, if the Common Stock is not listed on The NASDAQ Global Market, the principal other
U.S. national or regional securities exchange on which the Common Stock is then listed is open for trading, in each case with a scheduled closing time of 4:00 p.m. (New York City time) or the then-standard closing time for regular trading
on the relevant exchange or trading system, or, if the Common Stock is not so listed, any Business Day, and (ii) a Closing Sale Price for the Common Stock is available or (b) for purposes of determining Settlement Amounts pursuant to
Section 5.04 only, a day on which (i) there is no Market Disruption Event and (ii) The NASDAQ Global Market or, if the Common Stock is not listed on The NASDAQ Global Market, the principal other U.S. national or regional securities
exchange on which the Common Stock is then listed, is open for trading, in each case with a scheduled closing time of 4:00 p.m. (New York City time) or the then-standard closing time for regular trading on the relevant exchange or trading system,
or, if the Common Stock is not so listed, any Business Day. 

  
 10 

 “Trading Price” of the Notes means, on any date of determination, subject
to Section 5.01(a)(ii), the average of the secondary market bid quotations per $1,000 principal amount of Notes obtained by the Bid Solicitation Agent for $5,000,000 principal amount of the Notes at approximately 3:30 p.m. (New York City
time) on such determination date from three independent nationally recognized securities dealers the Company selects (any such bid quotation, a “Qualifying Bid”); provided that if at least three Qualifying Bids cannot
reasonably be obtained, but two Qualifying Bids can reasonably be obtained, then the average of these two Qualifying Bids shall be used; provided further that, if at least two Qualifying Bids cannot reasonably be obtained, but one Qualifying
Bid can reasonably be obtained, this one Qualifying Bid shall be used. 
 “Trading Price Condition” has the
meaning specified in Section 5.01(a)(ii). 
 “Trigger Event” has the meaning specified in
Section 5.06(c). 
 “U.S.” or “United States” means the United States of America.

 “Valuation Period” has the meaning specified in Section 5.06(c). 

Section 1.03. Section References. References to Articles, Sections, Exhibits, Annexes and Schedules are to Articles,
Sections, Exhibits, Annexes and Schedules of this Supplemental Indenture unless otherwise specified. 
 ARTICLE 2 

THE NOTES 
 Section 2.01. Designation, Amount and Issuance of Notes. The Notes shall be designated as “2.625% Convertible Senior Notes due 2017.” The Notes will be initially limited to an
aggregate principal amount of $258,750,000, subject to Section 2.08 of this Supplemental Indenture and except for Notes authenticated and delivered upon registration or transfer of, or in exchange for, or in lieu of, other Notes pursuant to
Sections 2.05, 2.06, 2.07 and 9.04 of the Original Indenture and Sections 2.06, 4.01, 5.03 and 6.04 of this Supplemental Indenture. 
 Section 2.02. Form of the Notes. The Notes and the Trustee’s certificate of authentication to be borne by such Notes shall be substantially in the form set forth in Exhibit A hereto. The
terms and provisions contained in the form of Notes attached as Exhibit A hereto shall constitute, and are hereby expressly made, a part of this Supplemental Indenture and, to the extent applicable, the Company and the Trustee, by their execution
and delivery of this Supplemental Indenture, expressly agree to such terms and provisions and to be bound thereby. 
 So long as
the Notes are eligible for book-entry settlement with the Depositary, or unless otherwise required by law, subject to Section 2.06 of this Supplemental Indenture, all of the Notes will be represented by one or more Global Securities. The
transfer and exchange of beneficial interests in any such Global Securities shall be effected through the Depositary in accordance with the Indenture and the applicable procedures of the Depositary. Except as provided in Section 2.06 of this
Supplemental Indenture, beneficial owners of a Global Security shall not be entitled to have certificates registered in their names, will not receive or be entitled to receive physical delivery of certificates in definitive form and will not be
considered Holders of such Global Security. 

  
 11 

 Any Global Security shall represent such of the Outstanding Notes as shall be specified
therein and shall provide that it shall represent the aggregate amount of Outstanding Notes from time to time endorsed thereon and that the aggregate amount of Outstanding Notes represented thereby may from time to time be increased or reduced to
reflect issuances, repurchases, redemptions, conversions, transfers or exchanges permitted hereby. Any endorsement of a Global Security to reflect the amount of any increase or decrease in the amount of Outstanding Notes represented thereby shall be
made by the Trustee or the custodian for the Global Security, at the direction of the Trustee, in such manner and upon instructions given by the Holder of such Notes in accordance with the Indenture. 

Section 2.03. Date and Denomination of Notes; Payment at the Stated Maturity Date; Payment of Interest. The Notes shall be
issuable in registered form without coupons in denominations of $1,000 principal amount and integral multiples thereof. Each Note shall be dated the date of its authentication and shall accrue Interest from the date specified on the face of the form
of Notes attached as Exhibit A hereto or from the most recent date to which Interest has been duly paid or provided for. 
 On
the Stated Maturity Date, each Holder shall be entitled to receive the principal amount of the Notes held. For the avoidance of doubt, with respect to Global Securities, principal and Interest will be paid by wire transfer to the Depositary or its
nominee in immediately available funds. 
 Section 2.03 of the Original Indenture shall be amended for purposes of the
Notes by inserting the words “and Section 4.01 hereof” immediately following the reference to “Section 2.01(a)(23)” in the third sentence of the first paragraph thereof. 

The second sentence of the second paragraph of Section 2.03 of the Original Indenture shall not apply to the Notes. 

Section 2.04. Security Registrar, Paying Agent and Conversion Agent. The Company agrees that the office or agency maintained
by the Company pursuant to Sections 2.05 and 4.02 of the Original Indenture, with respect to the Notes, shall be located in New York City. The Company shall also maintain an office in New York City where the Notes may be presented for conversion
(the “Conversion Agent”). The Company initially appoints the Trustee as the Conversion Agent and initially designates the office or agency maintained by the Company in New York City pursuant to Section 4.02 of the Original
Indenture as the place of payment for the Notes (the “Place of Payment”). 
 The Company shall enter into an
appropriate agency agreement with any Conversion Agent not a party to this Supplemental Indenture. The agreement shall implement the provisions of this Supplemental Indenture that relate to such agent. The Company shall notify the Trustee of the
name and address of any such agent. If the Company fails to maintain a Conversion Agent, the Trustee shall act as such and shall be entitled to appropriate compensation therefor pursuant to Section 7.06 of the Original Indenture. The Company
may act as Conversion Agent. 

  
 12 

 The Company may remove any Conversion Agent upon written notice to such Conversion Agent and
to the Trustee; provided that no such removal shall become effective until (1) acceptance of an appointment by a successor as evidenced by an appropriate agreement entered into by the Company and such successor Conversion Agent and
delivered to the Trustee or (2) notification to the Trustee that the Trustee shall serve as Conversion Agent until the appointment of a successor in accordance with clause (1) above. The Conversion Agent may resign at any time upon written
notice; provided that the Trustee may resign as Conversion Agent only if the Trustee also resigns as Trustee in accordance with Section 7.10 of the Original Indenture. If the Conversion Agent receives any cash or shares of Common Stock
hereunder, the Conversion Agent agrees to hold such cash or shares in trust for the sole benefit of the relevant Holders. 
 The
Company may appoint additional Conversion Agents and may approve any change in the office through which any Conversion Agent acts. 
 Section 2.05. Registration of Transfer and Exchange. Notwithstanding anything in Section 2.05 of the Original Indenture to the contrary, neither the Company nor the Trustee nor any
Security Registrar shall be required to exchange or register a transfer of (a) any Notes or portions thereof surrendered for conversion pursuant to Article 5, (b) any Notes or portions thereof tendered for repurchase (and not withdrawn)
pursuant to Section 4.01 or (c) any Notes or portions thereof surrendered for redemption pursuant to Article 6. 
 In
the event of any redemption of the Notes in part in accordance with Article 6, the Company shall not be required to (i) issue, register the transfer of or exchange any Notes during a period beginning at the open of business 15 days before any
selection for redemption of Notes and ending at the close of business on the earliest date on which the Redemption Notice is deemed to have been given to all Holders of Notes to be redeemed or (ii) register the transfer of or exchange any Notes
so selected for redemption, in whole or in part, except the unredeemed portion of any Notes being redeemed in part. 

Section 2.05(d) of the Original Indenture shall not apply to the Notes, and any reference in the Original Indenture to such
provision shall be deemed to refer to this Section 2.05. 
 Section 2.06. Global Securities. The following
provisions shall apply to Global Securities in addition to those provisions in Section 2.11 of the Original Indenture that are applicable to the Notes: 
 (a) For purposes of the Notes, Section 2.11(c) of the Original Indenture shall be superseded in its entirety by this Section 2.06(a), and any reference in the Original Indenture to such
Section 2.11(c) shall be deemed to refer to this Section 2.06(a). The Depositary will exchange the Global Security for Physical Securities that it will distribute to its participants if (i) the Depositary notifies the Company at any
time that it is unwilling or unable to continue as Depositary for the Global Securities and a successor Depositary is not appointed within 90 days; 

  
 13 

 
or (ii) the Depositary ceases to be registered as a clearing agency under the Exchange Act and a successor Depositary is not appointed within 90 days. If an Event of Default with respect to
the Notes has occurred and is continuing and any beneficial owner of a Note requests that its beneficial interest in a Global Security be exchanged for a Physical Security, the Depositary will exchange the corresponding portion of such Global
Security for a Physical Security, which it will distribute to such beneficial owner. 
 Notwithstanding anything to the contrary
in the Indenture (including, without limitation, Section 8.03 of the Original Indenture) or the Notes, following the occurrence and during the continuance of an Event of Default, any beneficial owner of a Global Security may directly enforce
against the Company, without the consent, solicitation, proxy, authorization or any other action of the Depositary or any other Person, such beneficial owner’s right to exchange its beneficial interest in such Global Security for a Physical
Security in accordance with this Section 2.06. 
 Notes issued in exchange for a Global Security or any portion thereof
pursuant to this Section 2.06(a) shall be issued in definitive, fully registered form, without Interest coupons, shall have an aggregate principal amount equal to that of such Global Securities or portion thereof to be so exchanged, shall be
registered in such names and be in such authorized denominations as the Depositary shall designate and shall bear any legends required under the Indenture. The form of legend set forth in Section 2.11(a) of the Original Indenture shall be
deemed replaced for purposes of the Notes with the legend set forth on the Form of Face of Security in Exhibit A hereto. 
 (b)
Upon any request by the Depositary or a beneficial owner in the circumstances described in Section 2.06(a), the Company will promptly make available to the Trustee a sufficient supply of Physical Securities in definitive, fully registered form,
without Interest coupons. 
 (c) At such time as all interests in a Global Security have been repurchased, converted, redeemed,
cancelled or exchanged for Notes in certificated form, such Global Security shall, upon receipt thereof, be canceled by the Trustee in accordance with standing procedures and instructions existing between the Depositary and the custodian for the
Global Security. At any time prior to such cancellation, if any interest in a Global Security is redeemed, repurchased, converted, cancelled or exchanged for Notes in certificated form, the principal amount of such Global Security shall, in
accordance with the standing procedures and instructions existing between the Depositary and the custodian for the Global Security, be appropriately reduced, and an endorsement shall be made on such Global Security, by the Trustee or the custodian
for the Global Security, at the direction of the Trustee, to reflect such reduction. The Company shall promptly notify the Trustee in writing of any repurchase, redemption, conversion, cancellation or exchange effected through any Paying Agent,
Security Registrar or Conversion Agent other than the Trustee. 
 Section 2.07. Purchase and Cancellation. The
Company may, to the extent permitted by law, and directly or indirectly (regardless of whether such Notes are surrendered to the Company), purchase Notes in the open market or by tender offer at any price or by private

  
 14 

 
agreement. Notwithstanding anything to the contrary in the Original Indenture, the Company shall cause any Notes so purchased (other than Notes purchased pursuant to cash-settled swaps or other
derivatives) to be surrendered to the Trustee for cancellation pursuant to Section 2.08 of the Original Indenture. 

Section 2.08. Additional Notes. The Company may, from time to time without the consent of the Holders of Outstanding Notes,
reopen the Indenture and issue additional Notes under the Indenture (“Additional Notes”) with the same terms (other than date of issuance and the date from which Interest will initially accrue) as the Notes issued on the Issue Date
in an unlimited amount; provided that if any such Additional Notes are not fungible for U.S. federal income tax purposes with the Notes issued on the Issue Date, such Additional Notes shall have a separate CUSIP number. The Notes issued on
the Issue Date and any Additional Notes shall be treated as a single class for all purposes under the Indenture, including waivers, amendments and offers to purchase. 
 Section 2.09. Mutilated, Destroyed, Lost or Stolen Notes. With respect to the Notes, the words “or is about to mature” in the first line of the second paragraph of Section 2.07
of the Original Indenture shall be deemed to have been deleted. 
 ARTICLE 3 

PARTICULAR COVENANTS OF THE COMPANY 

Section 3.01. Covenants in Original Indenture. The following covenants of the Company are made in addition to the covenants
set forth in Article 4 of the Original Indenture. 
 Section 3.02. [Reserved]. 

Section 3.03. Compliance Certificate. The Company shall deliver to the Trustee, as promptly as practicable and in any event
within 30 days after the Company becomes aware of the occurrence of any Event of Default or Default, an Officer’s Certificate setting forth the details of such Event of Default or Default, its status and the action which the Company proposes to
take with respect thereto. Any notice required to be given under this Section 3.03 shall be delivered to a Responsible Officer of the Trustee at its Corporate Trust Office. 

In addition, the Company shall deliver to the Trustee within 120 days after the end of each fiscal year of the Company (beginning with
the fiscal year ending December 31, 2012) an Officer’s Certificate stating whether or not the signers thereof have knowledge of any failure by the Company to comply with all conditions and covenants then required to be performed under the
Indenture and, if so, specifying each such failure and the nature thereof. 
 Section 3.04. Further Instruments and
Acts. Upon request of the Trustee, the Company will execute and deliver such further instruments and do such further acts as may be reasonably necessary or proper to carry out more effectively the purposes of the Indenture. 

  
 15 

 ARTICLE 4 
 REPURCHASE OF NOTES 

Section 4.01. Right To Require Repurchase Upon a Fundamental Change. (a) If a Fundamental Change occurs, each Holder of
Notes shall have the option to require the Company to purchase for cash all or any portion of such Holder’s Notes that is equal to $1,000, or an integral multiple of $1,000, on the day of the Company’s choosing that is not less than 20 or
more than 35 Business Days after the date of the Fundamental Change Purchase Right Notice (such day, the “Fundamental Change Purchase Date”) at a purchase price (the “Fundamental Change Purchase Price”) equal to
100% of the principal amount of the Notes to be purchased, plus accrued and unpaid Interest to but excluding the Fundamental Change Purchase Date (unless the Fundamental Change Purchase Date is after a Record Date and on or prior to the
Interest Payment Date to which it relates, in which case Interest accrued to the Interest Payment Date shall be paid to Holders of the Notes as of the preceding Record Date, and the purchase price the Company is required to pay to the Holder
surrendering the Note for purchase shall be equal to 100% of the principal amount of such Note subject to purchase and shall not include any accrued and unpaid Interest). 
 Purchases of Notes under this Section 4.01 shall be made, at the option of the Holder thereof, upon: 
 (i) delivery to the Trustee (or other Paying Agent appointed by the Company) by a Holder of a duly completed notice (the “Fundamental Change Purchase Notice”) in the form set forth on the
reverse of the Note during the period between the delivery of the Fundamental Change Purchase Right Notice and the close of business on the Business Day immediately preceding the Fundamental Change Purchase Date (the “Fundamental Change
Expiration Time”); and 
 (ii) delivery or book-entry transfer of the Notes to the Trustee (or other
Paying Agent appointed by the Company) at any time after delivery of the Fundamental Change Purchase Notice (together with all necessary endorsements, if the Notes are Physical Securities) at the Corporate Trust Office of the Trustee (or other
Paying Agent appointed by the Company), such delivery being a condition to receipt by the Holder of the Fundamental Change Purchase Price therefor. 
 The Fundamental Change Purchase Notice shall state: 
 (A) if
certificated, the certificate numbers of Notes to be delivered for purchase; 
 (B) the portion of the principal
amount of Notes to be purchased, which must be $1,000 or an integral multiple thereof; and 
 (C) that the Notes
are to be purchased by the Company pursuant to the applicable provisions of the Notes and the Indenture; 

  
 16 

 provided, however, that if the Notes are Global Securities, the Fundamental Change Purchase
Notice must comply with applicable Depositary procedures. 
 The Company shall be required to purchase, pursuant to subsection
(d), Notes that have been validly surrendered and not withdrawn on the Fundamental Change Purchase Date pursuant to subsection (c) of this Section 4.01. 
 The Trustee (or other Paying Agent appointed by the Company) shall promptly notify the Company of the receipt by it of any Fundamental Change Purchase Notice or written notice of withdrawal thereof in
accordance with the provisions of subsection (c) of this Section 4.01. 
 Any Note that is to be purchased only in
part shall be, if certificated, surrendered to the Trustee (with, if the Company or the Trustee so requires, due endorsement by, or a written instrument of transfer in form satisfactory to the Company and the Trustee duly executed by the Holder
thereof or his attorney duly authorized in writing), and the Company shall execute, and the Trustee shall authenticate and make available for delivery to the Holder of such Note without service charge, a new Note or Notes, containing identical terms
and conditions, each in an authorized denomination in aggregate principal amount equal to and in exchange for the unpurchased portion of the principal of the Note so surrendered, or, if a Global Security, the Trustee, or the custodian at the
direction of the Trustee, shall make a notation on such Global Security as to the reduction in the principal amount represented thereby for the purchased portion of the principal of the Note. 

(b) The Company shall mail to the Trustee and to each Holder a written notice of the Fundamental Change within ten Business Days after
the occurrence of such Fundamental Change (such notice the “Fundamental Change Purchase Right Notice”). Such mailing shall be by first class mail. 
 Each Fundamental Change Purchase Right Notice shall specify (if applicable): 
 (i) the events causing the Fundamental Change; 
 (ii) the effective
date of the Fundamental Change and whether the Fundamental Change is a Make-Whole Adjustment Event, in which case the notice shall state the Effective Date of the Make-Whole Adjustment Event; 

(iii) the procedures required for exercise of the Holder’s conversion right, and that the Notes with respect to which
a Fundamental Change Purchase Notice has been delivered by a Holder may be converted only if the Holder withdraws the Fundamental Change Purchase Notice in accordance with the terms of the Indenture; 

(iv) the last date on which a Holder may exercise the purchase right pursuant to this Article 4; 

(v) the Fundamental Change Purchase Price; 

  
 17 

 (vi) the Fundamental Change Purchase Date; 

(vii) the Conversion Rate and any adjustments to the Conversion Rate; 

(viii) the procedures required for exercise of the purchase option upon the Fundamental Change, and for withdrawal of a
Fundamental Change Purchase Notice; and 
 (ix) the name and address of the Paying Agent and the Conversion
Agent. 
 No failure of the Company to give the foregoing notices and no defect therein shall limit the Holders’ repurchase
rights or affect the validity of the proceedings for the repurchase of the Notes pursuant to this Section 4.01. 
 (c) A
Fundamental Change Purchase Notice may be withdrawn, in whole or in part, by means of a written notice of withdrawal delivered to the Paying Agent in accordance with the Fundamental Change Purchase Right Notice at any time until the Fundamental
Change Expiration Time, specifying: 
 (i) the principal amount of the Notes with respect to which such notice of
withdrawal is being submitted, 
 (ii) if certificated Notes have been issued, the certificate numbers of the
withdrawn Notes, 
 (iii) the principal amount, if any, of such Note that remains subject to the original
Fundamental Change Purchase Notice, which portion must be in principal amounts of $1,000 or an integral multiple of $1,000; 
 provided,
however, that if the Notes are not in certificated form, the withdrawal notice must comply with appropriate procedures of the Depositary. 
 (d) On or prior to 11:00 a.m., New York City time, on the Fundamental Change Purchase Date, the Company shall deposit with the Trustee (or other Paying Agent appointed by the Company or if the Company is
acting as its own Paying Agent, set aside, segregate and hold in trust) an amount of money sufficient to purchase on the Fundamental Change Purchase Date all of the Notes to be repurchased on such date at the Fundamental Change Purchase Price.
Subject to receipt of funds and/or Notes by the Trustee (or other Paying Agent appointed by the Company), payment for each Note surrendered for purchase (and not withdrawn) prior to the Fundamental Change Expiration Time shall be made promptly
following the later of (x) the Fundamental Change Purchase Date with respect to such Note (provided the Holder has satisfied the conditions to the payment of the Fundamental Change Purchase Price in this Section 4.01), and
(y) the time of book-entry transfer or the delivery of such Note to the Trustee (or other Paying Agent appointed by the Company) by the Holder thereof in the manner required by this Section 4.01 by mailing checks for the amount payable to
the Holders of such Notes entitled thereto as they shall appear in the Security Register; provided, however, that payments to the Depositary shall be made by wire transfer of immediately available funds to the account of the

  
 18 

 
Depositary or its nominee. The Trustee (or other Paying Agent) shall, promptly after such payment and upon written demand by the Company, return to the Company any funds in excess of the
Fundamental Change Purchase Price. 
 (e) If the Trustee (or other Paying Agent appointed by the Company) holds money sufficient
to purchase on the Fundamental Change Purchase Date all the Notes or portions thereof that are to be purchased as of the Business Day following the Fundamental Change Purchase Date, then on and after the Fundamental Change Purchase Date
(i) such Notes shall cease to be Outstanding and Interest, if any, shall cease to accrue on such Notes, whether or not book-entry transfer of the Notes has been made and whether or not the Notes have been delivered to the Trustee or Paying
Agent and (ii) all other rights of the Holders of such Notes shall terminate, other than (A) the right to receive the Fundamental Change Purchase Price upon delivery or transfer of the Notes, and (B) if the Fundamental Change Purchase
Date falls after a Record Date and on or prior to the related Interest Payment Date the right of the Holder on such Record Date to receive the Interest payable on such Interest Payment Date. 

(f) In connection with any purchase of Notes pursuant to this Article 4, the Company shall: 

(i) comply with the provisions of Rule 13e-4, Rule 14e-1 and any other tender offer rules under the Exchange Act to the
extent any such rules are applicable; 
 (ii) file a Schedule TO or any successor or similar schedule, if
required, under the Exchange Act; and 
 (iii) otherwise comply with all federal and state securities laws in
connection with any offer by the Company to purchase the Notes upon a Fundamental Change. 
 (g) Notwithstanding anything to the
contrary herein, no Notes may be purchased by the Company at the option of Holders upon a Fundamental Change if the principal amount of the Notes has been accelerated, and such acceleration has not been rescinded, on or prior to the relevant
Fundamental Change Purchase Date (except in the case of an acceleration resulting from the Company’s default in the payment of the Fundamental Change Purchase Price with respect to such Notes). 

ARTICLE 5 

CONVERSION 
 Section 5.01. Conversion Privilege and Conversion Rate. (a) Subject to the conditions and during the periods described in subsections (a)(i), (ii), (iii) and (iv), (b), (c) and
(d) below, and upon compliance with the provisions of this Article 5, a Holder shall have the right to surrender for conversion all or any portion (if the portion to be converted is $1,000 principal amount or an integral multiple thereof) of
its Note at any time until the close of business on the Business Day immediately preceding the Free Convertibility Date. On and after the Free Convertibility Date and until the close of business on the second Business Day immediately prior

  
 19 

 
to the Stated Maturity Date, a Holder shall have the right to surrender all or any portion (if the portion to be converted is $1,000 principal amount or an integral multiple thereof) of its Note
for conversion, regardless of whether any of the conditions described in subsections (a)(i), (ii), (iii) and (iv), (b), (c) and (d) below have been satisfied, upon compliance with the provisions of this Article 5. 

(i) Prior to the close of business on the Business Day immediately preceding the Free Convertibility Date, a Holder may
surrender all or any portion of its Notes for conversion during any calendar quarter commencing after the quarter ending June 30, 2012 if the Closing Sale Price of the Common Stock for at least twenty (20) Trading Days (whether or not
consecutive) in the period of thirty (30) consecutive Trading Days ending on the last Trading Day of the calendar quarter immediately preceding the calendar quarter in which the conversion occurs, is more than 130% of the Conversion Price of
the Notes in effect on each applicable Trading Day. 
 (ii) If, prior to the close of business on the Business
Day immediately preceding the Free Convertibility Date, the Trading Price per $1,000 in principal amount of the Notes on each Trading Day during any five consecutive Trading Day period is less than 98% of (x) the Closing Sale Price of the
Common Stock on such Trading Day multiplied by (y) the Conversion Rate in effect on such Trading Day, a Holder may surrender its Notes for conversion at any time during the following five consecutive Trading Days (the “Trading
Price Condition”). 
 The Bid Solicitation Agent shall, on behalf of the Company, determine if the Notes
are convertible pursuant to this Section 5.01(a)(ii) and shall notify the Company and the Trustee accordingly; provided that the Bid Solicitation Agent shall have no obligation to determine the Trading Price of the Notes unless the
Company has requested such determination in writing, and the Company shall have no obligation to make such request unless a Holder provides the Company and the Trustee with reasonable evidence that the Trading Price of the Notes on any Trading Day
would be less than 98% of the product of the then-current Conversion Rate multiplied by the Closing Sale Price of the Common Stock on that date. At such time, the Company shall instruct the Bid Solicitation Agent to determine the Trading
Price of the Notes beginning on such Trading Day and on each of the next four Trading Days. If (x) the Company does not, when it is required to do so, instruct the Bid Solicitation Agent to obtain Qualifying Bids, or if the Company gives such
instruction to the Bid Solicitation Agent and the Bid Solicitation Agent fails to make such determination (including, for the avoidance of doubt, because the Bid Solicitation Agent cannot reasonably obtain at least one Qualifying Bid), or
(y) if the Company is acting as Bid Solicitation Agent and the Company fails to make such determination, then, in either case, the Trading Price per $1,000 principal amount of the Notes shall be deemed to be less than 98% of the product of the
Closing Sale Price of the Common Stock and the Conversion Rate for each Trading Day on which such failure occurs. 
 If the Trading Price Condition has been met, the Company shall so notify the Holders, the Trustee and the Conversion Agent (if other than the Trustee) within two

  
 20 

 
Business Days. If, at any time after the Trading Price Condition has been met, the Trading Price per $1,000 principal amount of Notes is greater than or equal to 98% of the product of the Closing
Sale Price of the Common Stock and the Conversion Rate for such Trading Day, the Company shall promptly so notify the Holders, the Trustee and the Conversion Agent (if other than the Trustee). 

(iii) The Notes shall be convertible prior to the close of business on the Business Day immediately preceding the Free
Convertibility Date under the circumstances and during the periods set forth in subsections (b), (c) and (d) of this Section 5.01. 
 (iv) If the Company calls any or all of the Notes for redemption pursuant to Article 6, Holders of the Notes shall have the right to convert their Notes at any time until the close of business on the
second Business Day preceding the related Redemption Date, after which time Holders shall no longer have the right to convert their Notes on account of the Company’s delivery of the related Redemption Notice unless the Company defaults in the
payment of the Redemption Price. 
 (b) If, prior to the close of business on the Business Day immediately preceding the Free
Convertibility Date, the Company elects to issue or distribute, as the case may be, to all or substantially all holders of Common Stock: 
 (i) rights, options or warrants entitling them to subscribe for or purchase, for a period expiring within 60 days after the record date for such issuance, Common Stock at a price per share that is less
than the Closing Sale Price on the declaration date for such issuance; or 
 (ii) cash, debt securities (or
other evidence of indebtedness) or other assets or securities (excluding dividends or distributions described in Section 5.06(a)), which distribution has a per share value, as determined by the Board of Directors exceeding 10% of the Closing
Sale Price of Common Stock as of the Trading Day immediately preceding the declaration date for such distribution, 
 then, in either case, the
Company shall notify Holders at least 25 Scheduled Trading Days prior to the Ex-Dividend Date for such distribution. Once the Company has given such notice, Holders may surrender their Notes for conversion at any time until the earlier of the
close of business on the Business Day immediately preceding the Ex-Dividend Date and the Company’s announcement that such issuance or distribution will not take place. 
 (c) If a transaction or event that constitutes a Fundamental Change or a Make-Whole Adjustment Event occurs prior to the close of business on the Business Day immediately preceding the Free Convertibility
Date, a Holder may surrender its Notes for conversion at any time from and after the effective date of such transaction or event until the close of business on the second Business Day immediately preceding the related Fundamental Change Purchase
Date or, if there is no such Fundamental Change Purchase Date, the 30th Scheduled Trading Day immediately following the effective date of such transaction or event. 

  
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 (d) If the Company is a party to a consolidation, merger or binding share exchange or a
sale, assignment, conveyance, transfer, lease or other disposition of all or substantially all of its property and assets that does not also constitute a Fundamental Change or a Make-Whole Adjustment Event, in each case pursuant to which the Common
Stock would be converted into cash, securities or other property, a Holder shall have the right to surrender its Notes for conversion at any time beginning on the earlier of (i) the date on which the Company gives notice or makes a public
announcement of such transaction and (ii) the effective date of such transaction, and ending on the 20th Scheduled Trading Day following the effective date of such transaction. To the extent practicable, the Company shall notify Holders at
least 25 Scheduled Trading Days prior to the anticipated effective date of such transaction, and in no event later than the actual effective date. 
 Section 5.02. Conversion Rate Adjustment Upon Certain Make-Whole Adjustment Events. (a) If a Holder elects to convert its Note at any time from, and including, the Effective Date of a
Make-Whole Adjustment Event to, and including, the Business Day immediately preceding the related Fundamental Change Purchase Date, or if a Make-Whole Adjustment Event does not also constitute a Fundamental Change, the 30th Scheduled Trading Day
immediately following the Effective Date of such Make-Whole Adjustment Event, the Conversion Rate shall be increased by an additional number of shares of Common Stock (the “Additional Shares”) determined pursuant to subsection
(b) below. The Company shall notify Holders, the Trustee and the Conversion Agent of the anticipated Effective Date of any event that, if consummated, would constitute a Make-Whole Adjustment Event, and issue a press release containing the
information in such notice, as soon as practicable following the first public announcement of such potential Make-Whole Adjustment Event. 
 (b) The number of Additional Shares, if any, by which the Conversion Rate shall be increased for conversions in connection with a Make-Whole Adjustment Event as set forth in clause (a) above shall be
determined by reference to the table attached as Schedule A hereto, based on the date on which the Make-Whole Adjustment Event occurs or becomes effective (the “Effective Date”) and the Stock Price. The exact Stock Price and
Effective Date may not be set forth in the table attached as Schedule A hereto, in which case if the Stock Price is: 
 (i) between two Stock Prices in the table or the Effective Date is between two Effective Dates in the table, the number of Additional Shares shall be determined by a straight-line interpolation between
the number of Additional Shares set forth for the higher and lower Stock Price amounts or the earlier and later Effective Dates based on a 365-day year, as applicable; 

(ii) in excess of $200.00 per share (subject to adjustment in the same manner as the Stock Prices pursuant to subsection
(c) below), no Additional Shares shall be added to the Conversion Rate; and 
 (iii) less than $71.41 per
share (subject to adjustment in the same manner as the Stock Prices pursuant to subsection (c) below), no Additional Shares shall be added to the Conversion Rate. 

  
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 Notwithstanding anything herein to the contrary, the Company shall not increase the Conversion Rate to more
than 14.0036 shares of Common Stock (the “Maximum Conversion Rate”) per $1,000 in principal amount of Notes pursuant to the events described in this Section 5.02; provided the Company shall adjust the Maximum Conversion
Rate upon the occurrence of any event for which, and in the same manner in which, it must adjust the Conversion Rate pursuant to Section 5.06. 
 (c) The Stock Prices set forth in the first row of the table in Schedule A hereto (i.e., the column headers) and the number of Additional Shares in the table in Schedule A hereto shall be adjusted
as of any date on which the Conversion Rate of the Notes is adjusted as set forth in Section 5.06. The adjusted Stock Prices shall equal the Stock Prices applicable immediately prior to such adjustment, multiplied by a fraction, the
numerator of which is the applicable Conversion Rate immediately prior to the adjustment giving rise to the Stock Price adjustment and the denominator of which is the Conversion Rate as so adjusted. The numbers of Additional Shares within the table
attached as Schedule A hereto shall each be adjusted in the same manner and at the same time as the Conversion Rate as set forth in Section 5.06. 
 Section 5.03. Exercise of Conversion Privilege. (a) Before any Holder of a Note shall be entitled to convert the same as set forth above, such Holder shall (i) in the case of a
Global Security, transfer such Note to the Conversion Agent through the facilities of the Depositary and comply with the applicable conversion procedures of the Depositary in effect at that time and, if required, pay funds equal to Interest payable
on the next Interest Payment Date to which such Holder is not entitled as set forth in Section 5.04(d) and, if required, pay all taxes or duties, if any, as set forth in Section 5.09 and (ii) in the case of a Physical Security,
(A) complete and manually sign and deliver an irrevocable written notice to the Conversion Agent in the form set forth in Exhibit A hereto (or a facsimile thereof) (a “Conversion Notice”) at the office of the Conversion Agent
and shall state in writing therein the principal amount of Notes to be converted and the name or names (with addresses) in which such Holder wishes the certificate or certificates for any shares of Common Stock, if any, to be delivered upon
settlement of the conversion obligation to be registered, (B) surrender such Note, duly endorsed to the Company or in blank (and accompanied by appropriate endorsement and transfer documents), at the office of the Conversion Agent, (C) if
required, pay all transfer or similar taxes, if any, as set forth in Section 5.09 and (D) if required, pay funds equal to Interest payable on the next Interest Payment Date to which such Holder is not entitled as set forth in
Section 5.04(d). The Company shall pay any documentary, stamp or similar issue or transfer tax on the issuance of any shares of Common Stock upon conversion of the Notes, unless the tax is due because the holder requests such shares to be
issued in a name other than the holder’s name, in which case the holder shall pay the tax. A Note shall be deemed to have been converted on the date (the “Conversion Date”) that the Holder has complied with the requirements set
forth in this Section 5.03. 
 If the Holder of a Note has submitted such Note for purchase upon a Fundamental Change, such
Holder may only convert such Note if it withdraw its Fundamental Change Purchase Notice prior to the Fundamental Change Expiration Time, in accordance with Section 4.01(c). 

  
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 (b) In case any Note shall be surrendered for partial conversion, the Company shall execute
and the Trustee shall, upon receipt of an Officer’s Certificate, authenticate and deliver to or upon the written order of the Holder of the Note so surrendered, without charge to such Holder, a new Note or Notes in authorized denominations in
an aggregate principal amount equal to the unconverted portion of the surrendered Notes. 
 Section 5.04. Settlement of
Conversion Obligation. (a) Upon conversion of any Note, the Company shall pay or deliver, as the case may be, to converting Holders, in respect of each $1,000 principal amount of Notes being converted, either (1) cash, (2) shares
of Common Stock, together with cash, if applicable, in lieu of any fractional share of Common Stock in accordance with Section 5.05 or (3) a combination of cash and shares of Common Stock, at its election, as set forth in this
Section 5.04. 
 (i) All conversions on or after the Final Settlement Method Election Date shall be settled
with the same Settlement Method specified or deemed specified by the Company hereunder. If the Company has not delivered to the Trustee and all Holders a notice of its election of Settlement Method on or prior to the Final Settlement Method Election
Date, the Company shall, with respect to any conversions on or after the Final Settlement Method Election Date, be deemed to have elected to satisfy its conversion obligation in a combination of cash and shares of Common stock, if any, with a
Specified Dollar Amount of $1,000 (except that, with respect to any conversion during a Redemption Period, the Settlement Method shall be as set forth in the relevant Redemption Notice). 

(ii) For all conversions prior to the Final Settlement Method Election Date, the Company shall use the same Settlement
Method for all conversions occurring on any given Conversion Date. The Company shall use the same Settlement Method for all conversions during any Redemption Period. Except for any conversions that occur on or after the Final Settlement Method
Election Date or during a Redemption Period, the Company shall not have any obligation to use the same Settlement Method with respect to conversions that occur on different Conversion Dates, unless the Company has made the Irrevocable Election
pursuant to Section 5.04(a)(iii). If the Company elects a particular Settlement Method in connection with any conversion prior to the Final Settlement Method Election Date, unless the Company has made the Irrevocable Election pursuant to
Section 5.04(a)(iii) or the Conversion Date occurs during a Redemption Period, the Company shall inform Holders so converting through the Trustee of the Settlement Method the Company has selected (including the Specified Dollar Amount, if
applicable), no later than the second Trading Day immediately following the related Conversion Date. If the Company does not timely make such an election, or if the Company does not timely elect a Settlement Method or Specified Dollar Amount (if
applicable) for conversions during any Redemption Period, the Company shall be deemed to have elected to satisfy its conversion obligation through the payment or delivery, as the case may be, of a combination of cash and shares of Common Stock, if
any, with a Specified Dollar Amount of $1,000. If the Company elects to pay or deliver, as the case may be, a combination of cash and shares of Common Stock, if any, in respect of its 

  
 24 

 
conversion obligation, but the Company does not timely notify converting Holders of the Specified Dollar Amount per $1,000 principal amount of Notes, such Specified Dollar Amount shall be deemed
to be equal to $1,000. 
 (iii) Prior to the Final Settlement Method Election Date, the Company may, by notice to
Holders, at its option irrevocably elect to satisfy its conversion obligation in a combination of cash and shares of Common Stock, if any, with a Specified Dollar Amount of $1,000, for all conversions with a Conversion Date subsequent to the
Company’s delivery of such notice (any such election, an “Irrevocable Election”). 
 (iv)
The amount of cash, if any, and the number of shares of Common Stock, if any, that the Company is required to pay or deliver, as the case may be, in respect of any conversion of Notes (the “Settlement Amount”) shall be computed as
follows: 
 (A) if the Company elects to satisfy its conversion obligation by delivering shares of Common Stock
(plus cash in lieu of any fractional share), the Company shall deliver to the converting Holder in respect of each $1,000 principal amount of Notes being converted a number of shares of Common stock equal to the Conversion Rate in effect on the
Conversion Date; 
 (B) if the Company elects to satisfy its conversion obligation solely by paying cash, the
Company shall pay to the converting Holder, in respect of each $1,000 principal amount of Notes being converted, cash in an amount equal to the sum of the Daily Conversion Values for each of the 20 consecutive Trading Days during the related
Conversion Period; and 
 (C) if the Company elects (or is deemed to have elected) to satisfy its conversion
obligation by paying or delivering, as the case may be, a combination of cash and shares of Common Stock, the Company shall deliver to Holders, in respect of each $1,000 principal amount of Notes being converted, an amount of cash and shares of
Common Stock equal to the sum of the Daily Settlement Amounts for each of the 20 consecutive Trading Days during the related Conversion Period. 
 (v) The consideration due upon conversion of the Notes shall be paid or delivered, as the case may be, through the Conversion Agent. Such payment or delivery, as the case may be, shall be made
(A) three Business Days after the Conversion Date in the case where the Company’s Conversion Obligation consists solely of shares of Common Stock (other than cash in lieu of any fractional share) or (B) three Business Days after the
last day of the Conversion Period (in the case of any other Settlement Method); provided, however, that, if as of any Conversion Date occurring prior to the Final Settlement Method Election Date, the Common Stock has been replaced by
Reference Property consisting solely of cash pursuant to Section 5.12, the Company shall pay the conversion consideration due in respect of conversion on the third Trading Day immediately following the related Conversion Date, and,
notwithstanding anything to the contrary herein, no Conversion Period shall apply to those conversions. 

  
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 (b) Each conversion shall be deemed to have been effected immediately prior to the close of
business on the relevant Conversion Date; provided, however, that the Person in whose name any shares of Common Stock shall be issuable upon such conversion shall be treated as the Holder of record of such shares as of the close of
business on the Conversion Date (in the case of a Conversion Obligation that consists solely of shares of Common Stock (and cash in lieu of any fractional share)) or the last Trading Day of the relevant Conversion Period (in any other case).

 (c) Any cash amounts due upon conversion by a Holder of Notes surrendered for conversion shall be paid by the Company to such
Holder, or such Holder’s nominee or nominees. In addition, the Company shall issue, or shall cause to be issued, any shares of Common Stock due upon conversion to such Holder, or such Holder’s nominee or nominees, certificates or a
book-entry transfer through the Depositary (together with any cash in lieu of fractional shares). 
 (d) Upon conversion, a
Holder shall not receive any additional cash payment for accrued and unpaid Interest, if any, except as set forth in this clause (d), and the Company shall not adjust the Conversion Rate to account for accrued and unpaid Interest. Except as set
forth in this clause (d), the Company’s settlement of the conversion of a Note pursuant to this Section 5.04 shall be deemed to satisfy its obligation to pay the principal amount of such Note and accrued and unpaid Interest thereon, if
any, to, but not including, the relevant Conversion Date. Upon conversion of a Note into a combination of cash and shares of Common Stock, accrued and unpaid Interest shall be deemed to be paid first out of the cash paid upon such conversion.
Notwithstanding the foregoing, if a Note is converted after the close of business on a Record Date, the Holder of such Note at the close of business on such Record Date shall receive the Interest payable on such Note on the corresponding Interest
Payment Date notwithstanding such conversion. A Note surrendered for conversion after the close of business on any Record Date but prior to the open of business on the immediately following Interest Payment Date must be accompanied by payment of an
amount equal to the Interest that will be payable on such Interest Payment Date on the Note so converted; provided, however, that no such payment need be made: 

(i) if the Company has specified a Fundamental Change Purchase Date or a Redemption Date that is after a Record Date and
on or prior to the Business Day immediately following the corresponding Interest Payment Date; 
 (ii) with
respect to any Note surrendered for conversion following the Record Date immediately preceding the Stated Maturity Date; or 
 (iii) only to the extent of any overdue Interest, if any overdue Interest remains unpaid at the time of conversion with respect to such Note. 

Section 5.05. Fractions of Shares. The Company shall not issue any fractional share of Common Stock upon conversion of the
Notes and shall instead pay cash in lieu of any fractional share of Common Stock otherwise issuable upon conversion based on the Daily VWAP of the Common Stock on the relevant Conversion Date (if the Company elects to satisfy its conversion
obligation solely in shares of Common Stock) or based on the Daily VWAP on the last Trading Day of the relevant Conversion Period (in the case of any other Settlement Method). For each Note surrendered for conversion, if the Company has elected to
satisfy its conversion obligation 

  
 26 

 
in a combination of cash and shares of Common Stock, the full number of shares that shall be issued upon conversion thereof shall be computed on the basis of the aggregate Daily Settlement
Amounts for the applicable Conversion Period and any fractional share remaining after such computation shall be paid in cash. In addition, if more than one Note shall be surrendered for conversion at one time by the same Holder, the number of full
shares that shall be issued upon conversion thereof shall be computed on the basis of the aggregate principal amount of the Notes (or specified portions thereof) so surrendered. 

Section 5.06. Adjustment of Conversion Rate. The Conversion Rate shall be adjusted from time to time by the Company as
follows: 
 (a) If the Company issues shares of Common Stock as a dividend or distribution on all or substantially all shares of
Common Stock, or if the Company subdivides or combines the Common Stock, the Conversion Rate shall be adjusted based on the following formula: 
  

 
 where, 
 CR0 = the
Conversion Rate in effect immediately prior to the open of business on the Ex-Dividend Date for such dividend or distribution, or immediately prior to the open of business on the effective date of such subdivision or combination of Common Stock, as
the case may be; 
 CR = the Conversion Rate in effect immediately after the open of business on the Ex-Dividend Date for such
dividend or distribution, or immediately after the open of business on the effective date of such subdivision or combination of Common Stock, as the case may be; 

OS0 = the number of shares Common Stock outstanding immediately prior to the open of business on the Ex-Dividend Date for such
dividend or distribution, or immediately prior to the open of business on the effective date of such subdivision or combination of Common Stock, as the case may be; and 
 OS = the number of shares of Common Stock that would be outstanding immediately after giving effect to such dividend or distribution, or immediately after the effective date of such subdivision or
combination of Common Stock, as the case may be. 
 Any adjustment made under this subsection (a) shall become effective
immediately after the open of business on the Ex-Dividend Date for such dividend or distribution, or immediately after the open of business on the effective date of such subdivision or combination of Common Stock, as the case may be. If such
dividend, distribution, subdivision or combination described in this subsection (a) is declared but not so paid or made, the Conversion Rate shall be immediately readjusted, effective as of the date the Board of Directors determines not to pay
such dividend or distribution or to effect such subdivision or combination, to the Conversion Rate that would then be in effect if such dividend or distribution had not been declared or such subdivision or combination had not been announced.

  
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 (b) If an Ex-Dividend Date occurs for a distribution to all or substantially all holders of
the Common Stock of any rights, options or warrants entitling them for a period of not more than 60 calendar days after the record date for such distribution to subscribe for or purchase shares of Common Stock, at a price per share less than the
Closing Sale Price of the Common Stock on the Trading Day immediately preceding the declaration date of such distribution, the Conversion Rate shall be increased based on the following formula: 

 
 

 
 where, 
 CR0 = the
Conversion Rate in effect immediately prior to the open of business on the Ex-Dividend Date for such distribution; 
 CR = the
Conversion Rate in effect immediately after the open of business on the Ex-Dividend Date for such distribution; 
 OS0 = the number
of shares of Common Stock outstanding immediately prior to the open of business on the Ex-Dividend Date for such distribution; 

X = the total number of shares of Common Stock issuable pursuant to such rights, options or warrants; and 

Y = the number of shares of Common Stock equal to the aggregate price payable to exercise such rights, options or warrants divided
by the average of the Closing Sale Prices of Common Stock over the 10 consecutive Trading Day period ending on the Trading Day immediately preceding the announcement date for such distribution. 

Any increase made under this subsection (b) shall be made successively whenever any such rights, options or warrants are issued and
shall become effective immediately after the open of business on the Ex-Dividend Date for such distribution. If such distribution is not so paid or made, effective as of the date the Board of Directors determines not to make such distribution, the
Conversion Rate shall be decreased to be the Conversion Rate that would then be in effect if such distribution had not been declared. To the extent that shares of Common Stock are not delivered after the expiration of such rights, options or
warrants, the Conversion Rate shall be decreased to the Conversion Rate that would then be in effect had the increase with respect to the issuance of such rights, options or warrants been made on the basis of delivery of only the number of shares of
Common Stock actually delivered. If such rights, options or warrants are not so distributed, the Conversion Rate shall be decreased to the Conversion Rate that would then be in effect if the Ex-Dividend Date for such distribution had not occurred.

 For purposes of this subsection (b) and for purposes of Section 5.01(b)(i), in determining the aggregate price
payable for such shares of Common Stock, there shall be taken into account any consideration the Company receives for such rights, options or warrants and any amount payable on exercise thereof, with the value of such consideration if other than
cash to be determined in good faith by the Board of Directors. 

  
 28 

 (c) If an Ex-Dividend Date occurs for a distribution (the “Relevant
Distribution”) of shares of Capital Stock, evidences of indebtedness of the Company or other assets or property of the Company or rights, options or warrants to acquire Capital Stock or other securities of the Company, to all or
substantially all holders of the Common Stock, excluding: 
 (i) dividends or distributions and rights, options
or warrants as to which an adjustment was effected pursuant to Section 5.06(a) or Section 5.06(b); 

(ii) dividends or distributions paid exclusively in cash; 

(iii) Spin-Offs; 
 (iv) except as set forth in Section 5.15, rights issued pursuant to any stockholder rights plan adopted by the Company; and 

(v) any distribution pursuant to a Share Exchange Transaction of cash, securities or other property constituting Reference
Property, 
 then, in each such case, the Conversion Rate shall be adjusted based on the following formula: 

 
 

 
 where, 
 CR0 = the
Conversion Rate in effect immediately prior to the open of business on the Ex-Dividend Date for such distribution; 
 CR = the
Conversion Rate in effect immediately after the open of business on the Ex-Dividend Date for such distribution; 
 SP0 = the
average of the Closing Sale Prices of Common Stock over the 10 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the Ex-Dividend Date for such distribution; and 

FMV = the fair market value (as determined in good faith by the Board of Directors) of the shares of Capital Stock, evidences of
indebtedness, assets or property or rights, options or warrants distributed with respect to each outstanding share of Common Stock as of the open of business on the Ex-Dividend Date for such distribution. 

Any increase made under the above portion of this subsection (c) shall become effective immediately after the open of business on
the Ex-Dividend Date for such distribution. No adjustment pursuant to the above formula shall result in a decrease of the Conversion Rate; 

  
 29 

 
provided that if such distribution is not so paid or made, effective as of the date the Board of Directors determines not to make such distribution, the Conversion Rate shall be decreased
to be the Conversion Rate that would then be in effect if such distribution had not been declared. Notwithstanding the foregoing, if “FMV” (as defined above) is equal to or greater than “SP0” (as defined above), in lieu of the foregoing increase, each Holder
of a Note shall receive, in respect of each $1,000 principal amount thereof, at the same time and upon the same terms as holders of Common Stock, without having to convert its Notes, the amount and kind of the Relevant Distribution that such Holder
would have received if such Holder owned on the relevant record date a number of shares of Common Stock equal to the Conversion Rate in effect on the Ex-Dividend Date for the distribution. 

With respect to an adjustment pursuant to this subsection (c) where there has been an Ex-Dividend Date for a dividend or other
distribution on the Common Stock of shares of Capital Stock of any class or series, or similar equity interest, of or relating to a Subsidiary or other business unit, that are, or, when issued, will be, listed or admitted for trading on a U.S.
national securities exchange (a “Spin-Off”) the Conversion Rate shall be increased based on the following formula: 
  

 
 where, 
 CR0 = the
Conversion Rate in effect immediately prior to the open of business on the Ex-Dividend Date for the Spin-Off; 
 CR = the
Conversion Rate in effect immediately after the open of business on the Ex-Dividend Date for the Spin-Off; 
 FMV = the average
of the Closing Sale Prices of the Capital Stock or similar equity interest distributed to holders of Common Stock applicable to one share of Common Stock (determined by reference to the definition of Closing Sale Price set forth in Section 1.02
as if references therein to Common Stock were to such Capital Stock or similar equity interest) over the first five consecutive Trading Day period commencing on, and including, the Ex-Dividend Date for the Spin-Off (such period, the
“Valuation Period”); and 
 MP0 = the average of the Closing Sale Prices of the Common Stock over the Valuation Period. 

The adjustment to the Conversion Rate under the preceding paragraph of this subsection (c) shall be determined on the last day of
the Valuation Period but shall be given effect immediately after the open of business on the Ex-Dividend Date for the Spin-Off. If the Ex-Dividend Date for the Spin-Off is less than five Trading Days prior to, and including, the end of the
Conversion Period in respect of any conversion, references within this subsection (c) to five Trading Days shall be deemed to be replaced, solely in respect of such conversion, with such 

  
 30 

 
lesser number of Trading Days as have elapsed from, and including, the Ex-Dividend Date for the Spin-Off to, and including, the last Trading Day of such Conversion Period. In respect of any
conversion during the Valuation Period for any Spin-Off, references within this subsection (c) related to five Trading Days shall be deemed to be replaced with such lesser number of Trading Days as have elapsed from, and including, the
Ex-Dividend Date for such Spin-Off to, but excluding, the relevant Conversion Date. 
 Rights, options or warrants distributed
by the Company to all or substantially all holders of Common Stock, entitling the holders thereof to subscribe for or purchase shares of the Company’s Capital Stock, including Common Stock (either initially or under certain circumstances),
which rights, options or warrants, until the occurrence of a specified event or events (“Trigger Event”): (i) are deemed to be transferred with such shares of Common Stock; (ii) are not exercisable; and (iii) are also
issued in respect of future issuances of Common Stock, shall be deemed not to have been distributed for purposes of this subsection (c) (and no adjustment to the Conversion Rate under this subsection (c) shall be required) until the
occurrence of the earliest Trigger Event, whereupon such rights, options and warrants shall be deemed to have been distributed and an appropriate adjustment (if any is required) to the Conversion Rate shall be made under this subsection (c). Subject
to Section 5.15, if any such rights, options or warrants are subject to events, upon the occurrence of which such rights, options or warrants become exercisable to purchase different securities, evidences of indebtedness or other assets, then
the date of the occurrence of any and each such event shall be deemed to be the date of distribution and Ex-Dividend Date with respect to new rights, options or warrants with such rights (and a termination or expiration of the existing rights,
options or warrants without exercise by any of the holders thereof). Subject to Section 5.15, in the event of any distribution (or deemed distribution) of rights, options or warrants, or any Trigger Event or other event (of the type described
in the preceding sentence) with respect thereto that was counted for purposes of calculating a distribution amount for which an adjustment to the Conversion Rate under this subsection (c) was made, (1) in the case of any such rights,
options or warrants that shall all have been redeemed or repurchased without exercise by any holders thereof, the Conversion Rate shall be readjusted upon such final redemption or repurchase to give effect to such distribution or Trigger Event, as
the case may be, as though it were a cash distribution, equal to the per share redemption or repurchase price received by a holder or holders of Common Stock with respect to such rights, options or warrants (assuming such holder had retained such
rights or warrants), made to all holders of Common Stock as of the date of such redemption or repurchase, and (2) in the case of such rights, options or warrants that shall have expired or been terminated without exercise by any holders
thereof, the Conversion Rate shall be readjusted as if such rights, options and warrants had not been issued. 
 For purposes of
this subsection (c) and subsections (a) and (b) of this Section 5.06, any dividend or distribution to which this subsection (c) is applicable that also includes shares of Common Stock to which subsection (a) of this
Section 5.06 applies or rights, options or warrants to subscribe for or purchase shares of Common Stock to which subsection (b) of this Section 5.06 applies, shall be deemed instead to be (1) a dividend or distribution of the
shares of Capital Stock, evidences of indebtedness or other assets or property, other than such shares of Common Stock or such rights, options or warrants, to which this subsection (c) applies (and any

  
 31 

 
Conversion Rate adjustment required by this subsection (c) with respect to such dividend or distribution shall then be made) immediately followed by (2) a dividend or distribution of
such shares of Common Stock or such rights, options or warrants (and any further Conversion Rate adjustment required by subsections (a) and (b) of this Section 5.06 with respect to such dividend or distribution shall then be made),
except (A) the Ex-Dividend Date of such dividend or distribution shall under this subsection (c) be substituted as “the Ex-Dividend Date” within the meaning of subsection (a) and subsection (b) of this Section 5.06
and (B) any shares of Common Stock included in such dividend or distribution shall not be deemed “outstanding immediately prior to the open of business on the Ex-Dividend Date for such dividend or distribution, or immediately prior to the
open of business on the effective date of such subdivision or combination of Common Stock, as the case may be” within the meaning of subsection (a) of this Section 5.06 or “outstanding immediately prior to the open of business on
the Ex-Dividend Date for such distribution” within the meaning of subsection (b) of this Section 5.06. 
 (d) If
an Ex-Dividend Date occurs for a cash dividend or distribution to all, or substantially all, holders of outstanding Common Stock (other than any dividend or distribution in connection with the Company’s liquidation, dissolution or winding up),
the Conversion Rate will be increased based on the following formula: 
  
 

 
 where, 
 CR0 = the
Conversion Rate in effect immediately prior to the open of business on the Ex-Dividend Date for such distribution; 
 CR = the
Conversion Rate in effect immediately after the open of business on the Ex-Dividend Date for such distribution; 
 SP0 = the
average of the Closing Sale Prices of Common Stock over the 10 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the Ex-Dividend Date for such distribution; and 

C = the amount in cash per share the Company pays or distributes to all or substantially all holders of Common Stock. 

  
 32 

 Any increase made under this subsection (d) shall become effective immediately after
the open of business on the Ex-Dividend Date for such dividend or distribution. No adjustment pursuant to the above formula shall result in a decrease of the Conversion Rate; provided that if any dividend or distribution described in this
subsection (d) is declared but not so paid or made, effective as of the date the Board of Directors determines not to make or pay such dividend or distribution, the new Conversion Rate shall be readjusted to the Conversion Rate that would then
be in effect if such dividend or distribution had not been declared. 
 Notwithstanding the foregoing, if
“C” (as defined above) is equal to or greater than “SP0” (as defined above), in lieu of the foregoing increase, each Holder of a Note shall receive, for each $1,000 principal amount of Notes, at the same time and upon the same terms as holders of shares
of Common Stock, without having to convert its Notes, the amount of cash that such Holder would have received if such Holder owned on the relevant record date a number of shares of Common Stock equal to the Conversion Rate on the Ex-Dividend Date
for such cash dividend or distribution. 
 (e) If the Company or any of its Subsidiaries makes a payment in respect of a tender
or exchange offer (other than an odd lot tender offer) for Common Stock and, if the cash and value of any other consideration included in the payment per share of Common Stock exceeds the Closing Sale Price of Common Stock on the Trading Day next
succeeding the last date on which tenders or exchanges may be made pursuant to such tender or exchange offer (the “Expiration Date”), the Conversion Rate shall be increased based on the following formula: 

 
 

 
 where, 
 CR0 = the
Conversion Rate in effect immediately prior to the close of business on the Trading Day next succeeding the Expiration Date; 

CR = the Conversion Rate in effect immediately after the close of business on the Trading Day next succeeding the Expiration Date;

 AC = the aggregate value of all cash and any other consideration (as determined in good faith by the Board of Directors) paid
or payable for shares purchased in such tender or exchange offer; 
 OS0 = the number of shares of Common Stock outstanding immediately prior to
the time (the “Expiration Time”) such tender or exchange offer expires (prior to giving effect to such tender offer or exchange offer); 
 OS = the number of shares of Common Stock outstanding immediately after the Expiration Time (after giving effect to such tender offer or exchange offer); and 

  
 33 

 SP = the Closing Sale Price of Common Stock on the Trading Day next succeeding the
Expiration Date. 
 Any adjustment to the Conversion Rate under this subsection (e) shall be made immediately after the
close of business on the Trading Day next succeeding the Expiration Date. If the Company or one of its Subsidiaries is obligated to purchase Common Stock pursuant to any such tender or exchange offer described in this subsection (e) but is
permanently prevented by applicable law from effecting any such purchase or all such purchases are rescinded, the new Conversion Rate shall be readjusted to be the Conversion Rate that would then be in effect if such tender or exchange offer had not
been made. No adjustment pursuant to the above formula shall result in an decrease of the Conversion Rate. 
 (f) In addition to
those adjustments required by subsections (a), (b), (c), (d) and (e) of this Section 5.06, and to the extent permitted by applicable law and subject to the listing standards of The NASDAQ Global Market or any other securities exchange
or market on which the Common Stock is then listed, the Company in its sole discretion from time to time may increase the Conversion Rate by any amount for a period of at least 20 Business Days so long as such increase is irrevocable during such
period and the Board of Directors determines that such increase would be in the Company’s best interest. In connection with an increase in the Conversion Rate pursuant to the preceding sentence, the Company shall mail to the Holder of each Note
at its address set forth on the register maintained by the Security Registrar pursuant to Section 5.02 of the Original Indenture a notice of the increase at least 15 days prior to the date the increased Conversion Rate takes effect, and such
notice shall state the increased Conversion Rate and the period during which it will be in effect. In addition, the Company may also (but is not required to) increase the Conversion Rate to avoid or diminish any income tax to holders of Common Stock
or rights to purchase Common Stock in connection with a dividend or distribution of shares (or rights to acquire shares) of Common Stock or similar events. 
 (g) Notwithstanding anything to the contrary in clauses (a) through (e) above, if a Conversion Rate adjustment becomes effective on any Ex-Dividend Date as described above, and a Holder that has
converted its Note on or after such Ex-Dividend Date and on or prior to the related record date would be treated as the record holder of shares of Common Stock as of the related Conversion Date pursuant to Section 5.04(b) based on an adjusted
Conversion Rate for such Ex-Dividend Date, then, notwithstanding the foregoing Conversion Rate adjustment provisions, the Conversion Rate adjustment relating to such Ex-Dividend Date shall not be made for such converting Holder. Instead, such Holder
shall be treated as if such Holder were the record owner of the shares of Common Stock such Holder is entitled to receive upon conversion on an unadjusted basis and participate in the related dividend, distribution or other event giving rise to such
adjustment. 
 (h) Adjustments to the Conversion Rate shall be calculated to the nearest one-ten thousandth (1/10,000) of a
share. Notwithstanding anything in this Section 5.06 to the contrary, the Company shall not be required to adjust the Conversion Rate unless the adjustment would result in a change of at least 1% of the Conversion Rate; provided that the
Company shall carry forward any adjustments that are less than 1% of the Conversion Rate and make such carried forward adjustments (1) when the cumulative net effect of all adjustments not yet made will

  
 34 

 
result in a change of at least 1% of the Conversion Rate or (2) regardless of whether the aggregate adjustment is less than 1%, (i) upon any required purchases of the notes pursuant to
Article 4 in connection with a Fundamental Change, (ii) on each of the Trading Days within any Conversion Period and (iii) upon any conversion of Notes. 
 (i) For purposes of this Section 5.06, the number of shares of Common Stock at any time outstanding shall not include shares held in the treasury of the Company but shall include shares issuable in
respect of scrip certificates issued in lieu of fractions of shares of Common Stock. 
 (j) Whenever any provision of the
Indenture requires the Company to calculate Closing Sale Prices, Daily VWAPs, Daily Conversion Values, Daily Settlement Amounts or the Stock Price for purposes of a Make-Whole Adjustment Event over a span of multiple days, the Board of Directors
shall make appropriate adjustments to any such variable and/or, if applicable, the amount of cash or number of shares of Common Stock deliverable upon conversion to account for any adjustment to the Conversion Rate that becomes effective, or any
event requiring an adjustment to the Conversion Rate where the Ex-Dividend, Expiration Date or effective date of the event occurs, at any time during the period for which such Closing Sale Prices, Daily VWAPs, Daily Conversion Values, Daily
Settlement Amounts or the Stock Price is to be calculated. 
 (k) No adjustment to the Conversion Rate need be made for a given
transaction if each Holder of a Note will be entitled to participate in such transaction, without conversion of such Note, on the same terms and at the same time as the holder of a number of shares of Common Stock equal to (i) the principal
amount of such Holder’s Note divided by $1,000 and multiplied by (ii) the Conversion Rate would be entitled to participate. 
 Section 5.07. Notice of Adjustments of Conversion Rate. Whenever the Conversion Rate is adjusted as herein provided, the Company shall compute the adjusted Conversion Rate in accordance
herewith and shall prepare a certificate signed by the Chief Financial Officer or Controller of the Company setting forth the adjusted Conversion Rate and describing in reasonable detail the facts upon which such adjustment is based. Such
certificate shall promptly be filed with the Trustee and with the Conversion Agent (if other than the Trustee), and the Company shall issue a press release containing the relevant information (and make the press release available on its website).
Failure to deliver any such certificate or notice shall not affect the validity of such adjustment. 
 Section 5.08.
Company To Reserve Common Stock. The Company shall at all times and from time to time reserve and keep available, free from preemptive rights, out of its authorized but unissued Common Stock that is not committed for any other purpose, for the
purpose of issuance upon conversion of Notes, a number of shares of Common Stock equal to the product of (a) the Maximum Conversion Rate and (b) the aggregate principal amount of Outstanding Notes divided by $1,000. 

Section 5.09. Taxes on Conversions. The Company shall pay any and all documentary, stamp or similar issue or transfer taxes
that may be payable in respect of the issuance of shares of 

  
 35 

 
Common Stock upon any conversion of Notes hereunder; provided that the Company shall not be required to pay any tax that is due because the converting Holder requests such shares to be
issued in a name other than such Holder’s name, and no such issuance shall be made unless and until the Holder has paid to the Company the amount of any such tax or duty, or has established to the satisfaction of the Company that such tax or
duty has been paid. 
 Section 5.10. Certain Covenants. Before taking any action which would cause an adjustment
reducing the Conversion Rate below the then par value, if any, of the shares of Common Stock issuable upon conversion of the Notes, the Company shall take all corporate action that it reasonably determines is necessary to ensure that the Company may
validly and legally issue a number of shares of Common Stock equal to the Maximum Conversion Rate (giving effect to such prospective adjustment), and that such shares would be considered fully paid under applicable law. 

Section 5.11. Cancellation of Converted Notes. All Notes delivered to the Conversion Agent for conversion shall be delivered
to the Trustee or its agent and canceled by the Trustee as provided in Section 2.08 of the Original Indenture. 

Section 5.12. Provision in Case of Effect of Reclassification, Consolidation, Merger or Sale. (a) In the event of:

 (i) any recapitalization, reclassification or change of the Common Stock (other than changes resulting from a
subdivision or combination of the Common Stock); 
 (ii) a consolidation, merger, combination or binding share
exchange involving the Company; or 
 (iii) a sale, assignment, conveyance, transfer, lease or other disposition
to another Person of the Company’s property and assets as an entirety or substantially as an entirety, 
 in each case, in which holders of
outstanding Common Stock are entitled to receive cash, securities or other property for their shares of Common Stock (“Reference Property” and any such transaction or event, a “Share Exchange Transaction”), then the
Company or the successor or purchasing Person, as the case may be, shall execute with the Trustee a supplemental indenture permitted hereby providing that Holders of each $1,000 principal amount of Notes will be entitled thereafter to convert their
Notes into the kind and amount of Reference Property that a holder of a number of shares of Common Stock equal to the Conversion Rate immediately prior to such transaction would have owned or been entitled to receive upon such transaction;
provided that at and after the effective time of any such transaction, (i) the Company will continue to have the right to determine the form of consideration to be paid or delivered, as the case may be, upon conversion of Notes pursuant
to Section 5.04(a), (ii) any amount otherwise payable in cash upon conversion of the Notes pursuant to Section 5.04(a)(iv) will continue to be payable in cash, (iii) any shares of Common Stock that the Company would have been
required to deliver upon conversion of the Notes pursuant to Section 5.04(a)(iv) shall instead be deliverable in the amount and type of Reference Property that a holder of that number 

  
 36 

 
of shares of Common Stock would have received in such transaction and (iv) the Daily VWAP shall be calculated based on the value of a unit of Reference Property that a holder of one share of
Common Stock would have received in such transaction. If the Notes become convertible into Reference Property pursuant to this Section 5.12 or such a supplemental indenture, the Company shall notify the Trustee and issue a press release
containing the relevant information and make such press release available on the Company’s website. 
 For purposes of this
Section 5.12, the type and amount of consideration that holders of Common Stock are entitled to in the case of reclassifications, consolidations, mergers, combinations, binding share exchanges, sales or transfers of assets or other transactions
that cause Common Stock to be converted into the right to receive more than a single type of consideration because the holders of Common Stock have the right to elect the type of consideration they receive shall be deemed to be the weighted average
of the types and amounts of consideration received by the holders of Common Stock that affirmatively make such an election. The Company shall notify Holders of such weighted average as soon as practicable after such determination is made. If the
Holders receive only cash in any Share Exchange Transaction, then for all conversions that occur after the effective date of such Share Exchange Transaction and prior to the Final Settlement Method Election Date (i) the consideration due upon
conversion of each $1,000 principal amount of Notes shall be solely cash in an amount equal to the Conversion Rate in effect on the relevant Conversion Date (as may be increased by any Additional Shares), multiplied by the price paid per
share of Common Stock in such Share Exchange Transaction and (ii) the Company shall satisfy its conversion obligation by paying cash to converting Holders on the third Business Day immediately following the relevant Conversion Date. The Company
shall not become a party to any Share Exchange Transaction unless its terms are consistent with this Section 5.12. 
 (b)
The above provisions of this Section 5.12 shall similarly apply to successive Share Exchange Transactions. 

Section 5.13. Responsibility of Trustee for Conversion Provisions. The Trustee and any Conversion Agent, subject to the
provisions of Article 7 of the Original Indenture, shall not at any time be under any duty or responsibility to any Holder of Notes or to the Company to determine whether any facts exist which may require any adjustment of the Conversion Rate, or
with respect to the nature or extent of any such adjustment when made, or with respect to the method employed, herein or in any supplemental indenture provided to be employed, in making the same, or whether a supplemental indenture need be entered
into. Neither the Trustee nor any Conversion Agent, subject to the provisions of Article 7 of the Original Indenture, shall be responsible for any failure of the Company to make or calculate any cash payment or to issue, transfer or deliver any
shares of Common Stock or share certificates or other securities or property or cash upon the surrender of any Note for the purpose of conversion; and the Trustee and any Conversion Agent, subject to the provisions of Article 7 of the Original
Indenture, shall not be responsible for any failure of the Company to comply with any of the covenants of the Company contained in this Article 5. 

  
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 Section 5.14. Notice to Holders Prior to Certain Actions. In case of:

 (a) any action by the Company or any Subsidiary thereof that would require an adjustment to the Conversion Rate under
Section 5.06 or 5.15; 
 (b) any Share Exchange Transaction; 

(c) any voluntary or involuntary dissolution, liquidation or winding up of the Company or any of its Subsidiaries; or 

(d) any Merger Transaction; 

then, in each case (unless notice of such event is otherwise required pursuant to another provision of the Indenture excluding, for the avoidance of
doubt, Section 5.07), the Company shall cause to be filed with the Trustee and the Conversion Agent and to be mailed to each Holder at such Holder’s address appearing on the list of Holders provided for in Section 5.01 of the Original
Indenture, as promptly as practicable but in any event at least ten days prior to the applicable date specified in clause (x) or (y) below, a notice stating (x) the date on which a record is to be taken for the purpose of such action
by the Company or its Subsidiary or, if a record is not to be taken, the date as of which the holders of Common Stock of record are to be determined for the purposes of such action by the Company or its Subsidiary, or (y) the date on which such
Share Exchange Transaction, Merger Transaction, dissolution, liquidation or winding up is expected to become effective or occur, and, if applicable, the date as of which it is expected that holders of Common Stock of record shall be entitled to
exchange their Common Stock for securities or other property deliverable upon such Share Exchange Transaction, Merger Transaction, dissolution, liquidation or winding up. Failure to give such notice, or any defect therein, shall not affect the
operation of any provision herein consequent on such event. 
 Section 5.15. Stockholder Rights Plan. To the extent
that the Company’s Rights Agreement, dated December 4, 2006, with American Stock Transfer & Trust Company, or any other stockholder rights agreement (i.e., a poison pill), is in effect upon conversion of the Notes,
converting Holders of the Notes shall receive, in addition to any Common Stock received in connection with such conversion, the rights under such rights plan, unless prior to such conversion, the rights have separated from the Common Stock, in which
case the Conversion Rate shall be adjusted at the time of separation as if the Company distributed to all holders of Common Stock shares of the Company’s Capital Stock, evidences of indebtedness or other assets or property, pursuant to
Section 5.06(c), subject to readjustment in the event of the expiration, termination or redemption of such rights. 

ARTICLE 6 

REDEMPTION 
 Section 6.01. Original Indenture. This Article 6 supersedes Article 3 of the Original Indenture in its entirety, and any reference in the Original Indenture to such Article 3 or any provision
therein shall be deemed to refer to this Article 6 or the corresponding provision herein (if any), as the case may be. 

  
 38 

 Section 6.02. Redemption. The Notes shall not be redeemable by the Company prior
to April 6, 2015, and no sinking fund is provided for the Notes. On or after April 6, 2015, the Company may redeem (an “Optional Redemption”) any or all of the Notes, except for any Notes that the Company is required to
purchase pursuant to Article 4, in cash at a redemption price equal to 100% of the principal amount of the Notes to be redeemed, plus accrued and unpaid interest, if any, to, but excluding, the Redemption Date (the “Redemption
Price”) (unless the Redemption Date falls after a Record Date but on or prior to the immediately succeeding Interest Payment Date, in which case Interest accrued to the Interest Payment Date shall be paid to Holders of record of such Notes
on such Record Date, and the Redemption Price shall be equal to 100% of the principal amount of the Notes to be redeemed); provided that the Notes shall only be redeemable pursuant to this Article 6 if the Closing Sale Price of the Common
Stock for 20 or more Trading Days in a period of 30 consecutive Trading Days ending on the Trading Day immediately prior to the date of the Redemption Notice exceeds 130% of the applicable Conversion Price in effect on each such Trading Day.

 Section 6.03. Notice of Optional Redemption; Selection of Notes. 

(a) In case the Company exercises its Optional Redemption right to redeem all or, as the case may be, any part of the Notes pursuant to
Section 6.02, (i) the Company shall fix a date for redemption (each, a “Redemption Date”), (ii) the Company shall mail a notice of such Optional Redemption (a “Redemption Notice”) not more than 60
calendar days nor less than 35 calendar days prior to the Redemption Date to the Trustee, the Paying Agent (if other than the Trustee) and each Holder of Notes to be so redeemed as a whole or in part at its last address as the same appears on the
register maintained by the Security Registrar pursuant to Section 5.02 of the Original Indenture; and (iii) if fewer than all of the Notes are being redeemed, (A) the Trustee shall select the Notes or portions of Notes to be redeemed,
in principal amounts of $1,000 or multiples of $1,000, by lot, on a pro rata basis or by another method the Trustee considers reasonable, fair and appropriate in accordance with applicable procedures of the Depositary and (B) the Trustee
shall notify the Company promptly of the Notes or portions of Notes to be called for redemption. 
 (b) Each Redemption Notice
shall specify: 
 (i) the Redemption Date (which must be a Business Day); 

(ii) the Redemption Price; 
 (iii) that on the Redemption Date, the Redemption Price will become due and payable upon each such Note, and that Interest thereon, if any, shall cease to accrue on and after said date; 

(iv) the place or places where such Notes are to be surrendered for payment of the Redemption Price; 

  
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 (v) that Holders may surrender their Notes for conversion at any time prior
to the close of business on the second Business Day immediately preceding the Redemption Date in accordance with the procedures set forth in Article 5; 
 (vi) the procedures a converting Holder must follow to convert its Notes, the time at which the right of Holders to convert their Notes on account of the Company’s delivery of a Redemption Notice
shall expire pursuant to Section 5.01(a)(iv), and the Settlement Method (and, if applicable, the Specified Dollar Amount) that shall apply to any such conversions; 

(vii) the Conversion Rate then in effect and, if applicable, the number of Additional Shares added to the Conversion Rate
in accordance with Section 5.02; 
 (viii) the CUSIP, ISIN or other similar numbers, if any, assigned to
such Notes; and 
 (ix) in case any Note is to be redeemed in part only, the portion of the principal amount
thereof to be redeemed and on and after the Redemption Date, upon surrender of such Note, a new Note in principal amount equal to the unredeemed portion thereof shall be issued. 
 At the Company’s written request, the Trustee shall give the Redemption Notice to each Holder of Notes to be redeemed in the Company’s name and at the Company’s expense, provided,
however, that the Company has delivered to the Trustee, at least 5 days (unless a shorter time should be acceptable to the Trustee) prior to the notice date, an Officer’s Certificate requesting that the Trustee give such notice and
setting forth the information to be stated in such notice. 
 (c) If a portion of any Note is selected for redemption and the
Holder thereof converts a portion of such Note, the portion of the Note submitted for conversion shall be deemed to be the portion selected for redemption to the extent that the converted portion does not exceed the portion selected for redemption.

 Section 6.04. Payment of Notes Called for Redemption. 

(a) If any Redemption Notice has been given in respect of the Notes in accordance with Section 6.03, the Notes shall become due and
payable on the Redemption Date at the Place of Payment and at the applicable Redemption Price. On presentation and surrender of the Notes at the Place of Payment, the Notes shall be paid and redeemed by the Company at the applicable Redemption
Price. In the case of any redemption in part, the Company shall execute and the Trustee shall, upon receipt of an Officer’s Certificate, authenticate and deliver to or upon the written order of the Holder of the Note so surrendered, without
charge to such Holder, a new Note or Notes in authorized denominations in an aggregate principal amount equal to the unredeemed portion of the Note so surrendered. 
 (b) Prior to the open of business on the Redemption Date, the Company shall deposit with the Paying Agent or, if the Company is acting as the Paying Agent, shall segregate and hold

  
 40 

 
in trust an amount of cash (in immediately available funds if deposited on the Redemption Date), sufficient to pay the Redemption Price of all of the Notes to be redeemed on such Redemption Date.
Subject to receipt of funds by the Paying Agent, payment for any Note to be redeemed shall be made on the Redemption Date for such Note or, if later, at the time of presentation of such Note to the Trustee (or other Paying Agent appointed by the
Company) by the Holder thereof in the manner required by this Section 6.04. Commencing on the Redemption Date, if the Company has deposited, or has segregated and is holding in trust, such funds, the Notes to be redeemed shall cease to accrue
Interest. The Paying Agent shall, promptly following such payment and upon written demand by the Company, return to the Company any funds in excess of the Redemption Price. 
 Section 6.05. Restrictions on Redemption. Notwithstanding anything to the contrary herein, the Company may not redeem any Notes if the principal amount of the Notes has been accelerated in
accordance with the terms of this Indenture, and such acceleration has not been rescinded, on or prior to the Redemption Date (except in the case of an acceleration resulting from a default by the Company in the payment of the applicable Redemption
Price with respect to such Notes). 
 ARTICLE 7 
 EVENTS OF DEFAULT; REMEDIES 
 Section 7.01. Original Indenture. With respect to the Notes, (i) Section 7.02 hereof shall supersede Section 6.01(a) of the Original Indenture; (ii) the first
paragraph of Section 7.03 hereof shall supersede Section 6.01(b) of the Original Indenture; (iii) the second and third paragraphs of Section 7.03 hereof shall supersede Section 6.01(c) of the Original Indenture;
(iv) Section 7.05 hereof shall supersede the second paragraph of Section 6.04 of the Original Indenture; and (v) Section 7.06 hereof shall supersede the final two sentences of Section 6.06 of the Original Indenture, and any
reference in the Original Indenture to any such provision of the Original Indenture shall be deemed to refer to the corresponding provision herein (if any). The reference to “90 days” in clause (i) of Section 6.02(a) of the
Original Indenture shall be deemed replaced with “30 days.” 
 Section 7.02. Events of Default.

 In lieu of the “Events of Default” set forth in Section 6.01(a) of the Original Indenture, each of the
following events shall constitute an “Event of Default” hereunder: 
 (a) failure by the Company to pay the
principal of any Note when due; 
 (b) failure by the Company to pay or deliver, as the case may be, the Conversion Obligation
owing upon conversion of any Note (including any Additional Shares or cash in lieu thereof) within five calendar days; 
 (c)
failure by the Company to pay any Interest on any Note when due, and such failure continues for 30 days; 

  
 41 

 (d) failure by the Company to pay the Fundamental Change Purchase Price or Redemption Price
of any Note when due; 
 (e) failure by the Company to provide timely notice of a transaction or event, the occurrence (or
delivery by the Company of notice) of which would give rise to a right of Holders to convert their Notes pursuant to Section 5.01(b) or (d), or a Fundamental Change or a Make-Whole Adjustment Event, in accordance with the terms provided in
Section 4.01(b), 5.01(b), 5.01(d) or 5.02, as the case may be; 
 (f) failure by the Company to perform any other covenant
required of it as provided in the Indenture (other than a covenant or agreement a default in whose performance or whose breach is specifically dealt with in subsections (a) through (e) above) and such failure continues for 60 days
after written notice thereof has been received by the Company from the Trustee or the Holders of at least 25% in aggregate principal amount of the Notes then Outstanding; 
 (g) any indebtedness for money borrowed by, or any other payment obligation of, the Company or any of its Subsidiaries that is a Significant Subsidiary, in an outstanding principal amount, individually or
in the aggregate, in excess of $40 million is not paid at final maturity (or when otherwise due) or is accelerated, and such indebtedness is not discharged (or such default in payment or acceleration is not cured or rescinded) within
30 days after such due date or acceleration, as the case may be; 
 (h) failure by the Company or any of its Subsidiaries
that is a Significant Subsidiary to pay one or more final and non-appealable judgments entered by a court or courts of competent jurisdiction, the aggregate uninsured or unbonded portion of which is in excess of $40 million, if the judgments
are not paid, discharged or stayed within 30 days; and 
 (i) the Company or any Significant Subsidiary thereof shall
commence a voluntary case or other proceeding seeking liquidation, reorganization or other relief with respect to the Company or any such Significant Subsidiary or its debts under any bankruptcy, insolvency or other similar law now or hereafter in
effect or seeking the appointment of a trustee, receiver, liquidator, custodian or other similar official of the Company or any such Significant Subsidiary or any substantial part of its property, or shall consent to any such relief or to the
appointment of or taking possession by any such official in an involuntary case or other proceeding commenced against it, or shall make a general assignment for the benefit of creditors, or shall fail generally to pay its debts as they become due;
or 
 (j) an involuntary case or other proceeding shall be commenced against the Company or any Significant Subsidiary thereof
seeking liquidation, reorganization or other relief with respect to the Company or such Significant Subsidiary or its debts under any bankruptcy, insolvency or other similar law now or hereafter in effect or seeking the appointment of a trustee,
receiver, liquidator, custodian or other similar official of the Company or such Significant Subsidiary or any substantial part of its property, and such involuntary case or other proceeding shall remain undismissed and unstayed for a period of 90
consecutive days. 

  
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 Section 7.03. Acceleration of Maturity; Rescission and Annulment. If an Event of
Default, other than an Event of Default specified in Section 7.02(i) or Section 7.02(j) with respect to the Company, occurs and is continuing, then in every such case either the Trustee or the Holders of at least 25% in aggregate principal
amount of the Outstanding Notes may declare the principal amount of, and all accrued unpaid Interest on, the Notes to be due and payable immediately, by a notice in writing to the Company (and to the Trustee if given by the Holders), and upon any
such declaration such principal and Interest shall become immediately due and payable. If an Event of Default specified in Section 7.02(i) or Section 7.02(j) occurs with respect to the Company, the principal amount of, and accrued and
unpaid Interest, if any, on, all of the Notes shall become immediately due and payable without any declaration or other act of the Holders or any act on the part of the Trustee. 

At any time after such an acceleration but before a judgment or decree based on such acceleration, the Holders of a majority in aggregate
principal amount of the Outstanding Notes, by written notice to the Company and the Trustee, may rescind and annul such acceleration (other than with respect to an Event of Default under Sections 7.02(a) (including the Fundamental Change Purchase
Price and the Redemption Price)) if: 
 (i) such rescission and annulment will not conflict with any judgment or
decree of a court of competent jurisdiction; and 
 (ii) all Events of Default, other than the non-payment of the
principal amount on Notes that have become due solely by such acceleration, have been cured or waived as provided in Section 7.06. 
 No such rescission shall affect any subsequent default or impair any right consequent thereon. 
 Notwithstanding the foregoing and not withstanding the remedies afforded to Holders upon the occurrence and during the continuation of an Event of Default as set forth in Article 6 of the Original
Indenture, at the election of the Company, the sole remedy for an Event of Default relating to (i) the failure by the Company to file with the Trustee pursuant to Section 314(a)(1) of the Trust Indenture Act any documents or reports that
the Company is required to file with the SEC pursuant to Section 13 or 15(d) of the Exchange Act or (ii) the failure by the Company to comply with its reporting obligations to the Trustee and the SEC, under Section 9.01 hereof, shall,
for the 365 days after the occurrence of such an Event of Default, consist exclusively of the right to receive additional interest on the Notes (“Additional Interest”). For the first 180 days during which such Event of Default is
continuing, Additional Interest shall accrue on the Notes at a rate equal to 0.25% per annum of the principal amount of the Notes then Outstanding. If such Event of Default is still continuing on the 181st day after it first occurred, such
Additional Interest shall accrue during the next 185 days during which such Event of Default is continuing at a rate of 0.50% per annum of the principal amount of Notes then Outstanding. Any such Additional Interest shall be payable in the same
manner and on the same dates as the stated Interest payable on the Notes. If such Event of Default is continuing on the 366th day after such Event of Default first occurred, the Notes shall be subject to acceleration in accordance with the
provisions of this Section 7.03 as provided above. This paragraph and the 

  
 43 

 
two immediately succeeding paragraphs shall not affect the rights of Holders of Notes in the event of the occurrence of any other Event of Default. In the event the Company does not elect to pay
the Additional Interest upon an Event of Default in accordance with this paragraph, the Notes shall be subject to acceleration in accordance with the first paragraph of this Section 7.03. 

In order to elect to pay Additional Interest as the sole remedy during the first 365 days after the occurrence of an Event of Default
relating to the failure to comply with the reporting obligations set forth in Section 9.01 in accordance with the immediately preceding paragraph, the Company must notify in writing all Holders of record of Notes and the Trustee and Paying
Agent of such election on or before the close of business on the Business Day prior to the date on which such Event of Default would otherwise occur. Upon the Company’s failure to timely give such notice or pay Additional Interest, the Notes
shall be immediately subject to acceleration in accordance with the first paragraph of this Section 7.03. 
 If Additional
Interest is payable under this Section 7.03, the Company shall deliver to a Responsible Officer of the Trustee at the Corporate Trust Office a certificate to that effect stating that Additional Interest is payable and the date upon which such
Additional Interest shall begin to accrue. Unless and until a Responsible Officer of the Trustee receives at the Corporate Trust Office such a certificate, the Trustee may assume without inquiry that Additional Interest is not payable. If Additional
Interest has been paid by the Company directly to the persons entitled to it, the Company shall deliver to the Trustee a certificate setting forth the particulars of such payment. 

Payments of the Fundamental Change Purchase Price, Redemption Price, principal and Interest that are not made when due shall accrue
Interest per annum at the then-applicable interest rate. 
 Section 7.04. Limitation on Suits. The limitation on the
right of Holders to institute a proceeding under the Indenture or seek other remedies as set forth in the first paragraph of Section 6.04 of the Original Indenture shall not apply to a suit instituted by a Holder of Notes upon a default by the
Company in the payment of principal or Interest on the Notes or a failure by the Company to pay or deliver the consideration due upon conversion of any Note, in either case, when due. 

Section 7.05. Unconditional Right of Holders To Receive Payment. Notwithstanding any other provision of the Indenture or the
Notes, the right of any Holder to receive payment of the principal amount, Fundamental Change Purchase Price or accrued and unpaid Interest in respect of the Notes held by such Holder, on or after the respective due dates expressed in the Notes or
any Fundamental Change Purchase Date, as applicable, and to convert the Notes in accordance with Article 5, or to bring suit for the enforcement of any such payment on or after such respective dates or the right to convert, shall not be impaired or
affected adversely without the consent of such Holder. 
 Section 7.06. Waiver of Defaults and Events of Default.
Subject to Section 11.02, the Holders of not less than a majority of the aggregate principal amount of the Outstanding Notes may on behalf of the Holders of all of the Notes waive any Default or Event of Default hereunder, unless:

 (i) the Company fails to pay the principal of or any Interest on any Note when due; 

  
 44 

 (ii) the Company fails to pay or deliver the consideration due upon
conversion of any Note within the time period required herein; or 
 (iii) the Company fails to comply with any
of the provisions herein the modification of which would require the consent of the Holder of each Outstanding Note affected. 
 Upon any such
waiver, such Default or Event of Default shall cease to exist, and any Event of Default arising from such Default shall be deemed to have been cured, for every purpose of the Indenture; but no such waiver shall extend to any subsequent or other
Default or Event of Default or impair any right consequent thereon. 
 Section 7.07. Undertaking for Costs. The
provisions of Section 6.07 of the Original Indenture, in addition to the limitations set forth therein, shall not apply to any suit instituted by a Holder to enforce its right to receive the consideration due upon conversion of its Notes within
the time period prescribed herein. 
 Section 7.08. Waiver of Stay or Extension Laws. The Company covenants (to the
extent that it may lawfully do so) that it will not at any time insist upon, or plead, or in any manner whatsoever claim or take the benefit or advantage of, any stay, extension or usury law or other law which would prohibit or forgive the Company
from paying all or any portion of the principal of or Interest on the Notes as contemplated herein, wherever enacted, now or at any time hereafter in force, or which may affect the covenants or the performance of the Indenture; and the Company (to
the extent that it may lawfully do so) hereby expressly waives all benefit or advantage of any such law and covenants that it will not hinder, delay or impede the execution of any power herein granted to the Trustee, but will suffer and permit the
execution of every such power as though no such law had been enacted. 
 ARTICLE 8 

CONSOLIDATION, MERGER, CONVEYANCE, TRANSFER OR
LEASE 
 Section 8.01. Original Indenture. This Article 8 supersedes in its entirety Article 10 of
the Original Indenture, with the provisions of Section 8.02 of this Supplemental Indenture superseding the provisions of Section 10.01 of the Original Indenture and the provisions of Section 8.03 of this Supplemental Indenture
superseding Section 10.02 of the Original Indenture. In addition, each reference in the Original Indenture to Section 10.01 of the Original Indenture will, respect to the Notes, be deemed to be a reference to Section 8.02 of this
Supplemental Indenture. 

  
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 Section 8.02. Consolidation, Merger and Sale of Assets. The Company shall not
consolidate with, enter into a binding share exchange with, or merge with or into, another Person or sell, assign, convey, transfer, lease or otherwise dispose of its properties and assets substantially as an entirety to any successor Person (any
such transaction or series of transactions, a “Merger Transaction”), unless: 
 (a) the successor Person, if
any, is a corporation organized and existing under the laws of the United States, any state of the United States or the District of Columbia and expressly assumes by supplemental indenture all of the Company’s obligations under the Notes and
the Indenture; 
 (b) immediately after giving effect to such transaction, no Default or Event of Default shall have occurred
and be continuing; and 
 (c) if a supplemental indenture is required in connection with such Merger Transaction, the Company
shall have delivered to the Trustee an Officer’s Certificate and an Opinion of Counsel, each stating that such Merger Transaction and such supplemental indenture comply with this Article 8. 

Section 8.03. Successor Substituted. Upon any such Merger Transaction, the successor Person shall succeed to, and be
substituted for, and may exercise every right and power of, the Company under the Indenture with the same effect as if such successor had been named as the Company herein; and thereafter, and the Company shall be discharged from its obligations
under the Notes and this Indenture, except in the case of any lease of all or substantially all of the Company’s assets. 

ARTICLE 9 

REPORTS BY COMPANY 
 Section 9.01. Reports by Company.  
 This Section 9.01(a)
supersedes in its entirety Section 5.03(a) of the Original Indenture and any reference in the Original Indenture to such Section 5.03(a) or any provision therein shall be deemed to refer to this Section 9.01(a) and the corresponding
provision herein (if any). So long as any Notes are Outstanding, the Company shall (i) file with the SEC within the time periods prescribed by its rules and regulations and (ii) furnish to the Trustee and the Holders of the Notes within 15
days after the date on which the Company would be required to file the same with the SEC pursuant to its rules and regulations (giving effect to any grace period provided by Rule 12b-25 under the Exchange Act), all quarterly and annual financial
information required to be contained in Forms 10-Q and 10-K. The Company shall not be required to file any report or other information with the SEC if the SEC does not permit such filing, although such reports shall be required to be furnished to
the Trustee. Documents filed by the Company with the SEC via the Electronic Data Gathering and Retrieval (EDGAR) system (or any successor system) shall be deemed to have been furnished to the Trustee and the Holders of the Notes as of the time such
documents are filed via EDGAR. The Trustee shall have no responsibility whatsoever to determine if such filings have been made. 

  
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 ARTICLE 10 
 SATISFACTION AND DISCHARGE 

Section 10.01. Original Indenture. This Article 10 supersedes in its entirety the corresponding provisions set forth in
Article 11 of the Original Indenture and any reference in the Original Indenture to such Article 11 or any provision therein shall be deemed to refer this Article 10 or the corresponding provision herein (if any), as the case may be. For the
avoidance of doubt, the reference in Section 4.03(c) of the Original Indenture to “Section 11.05” shall be deemed replaced with a reference to the second paragraph of Section 10.04 hereof. 

Section 10.02. Discharge of Indenture. When (a) the Company shall deliver to the Trustee for cancellation all
Outstanding Notes theretofore authenticated (other than any Notes that have been destroyed, lost or stolen and in lieu of or in substitution for which other Notes shall have been authenticated and delivered) and not theretofore canceled, or
(b) all the Outstanding Notes not theretofore canceled or delivered to the Trustee for cancellation shall have become due and payable (whether at the Stated Maturity Date, on any Redemption Date or on any Fundamental Change Purchase Date or
upon conversion and determination of related Settlement Amounts or otherwise) and the Company shall deposit with the Trustee, in trust, cash funds and (in the case of conversion) shares of Common Stock, if any, sufficient to pay all amounts due on
all of such Outstanding Notes including principal and Interest due or satisfy the Company’s conversion obligation, as the case may be, (other than any Notes that shall have been mutilated, destroyed, lost or stolen and in lieu of or in
substitution for which other Notes shall have been authenticated and delivered) not theretofore canceled or delivered to the Trustee for cancellation, and, in each case, the Company shall also pay or cause to be paid all other sums payable under the
Indenture by the Company, then the Indenture shall cease to be of further effect (except as to (i) remaining rights of registration of transfer, substitution and exchange and conversion of Notes, (ii) rights hereunder of Holders to receive
payments of principal of and Interest on, or the consideration due upon conversion of, the Notes and the other rights, duties and obligations of Holders, as beneficiaries hereof with respect to the amounts, if any, so deposited with the Trustee and
(iii) the rights, obligations and immunities of the Trustee hereunder), and the Trustee, on written demand of the Company accompanied by an Officer’s Certificate and an Opinion of Counsel as may be required pursuant to Section 7.02(k)
of the Original Indenture and at the cost and expense of the Company, shall execute proper instruments acknowledging satisfaction and discharge of the Indenture. The Company, however, hereby agrees to reimburse the Trustee for any costs or expenses
thereafter reasonably and properly incurred by the Trustee and to compensate the Trustee for any services thereafter reasonably and properly rendered by the Trustee in connection with the Indenture or the Notes. 

Section 10.03. Deposited Monies and Shares To Be Held in Trust by Trustee. Subject to Section 10.04, all monies and
shares of Common Stock, if any, deposited with the Trustee pursuant to Section 10.02 shall be held in trust for the sole benefit of the Holders, and such 

  
 47 

 
monies and shares of Common Stock, if any, shall be applied by the Trustee to the payment, either directly or through the Paying Agent or Conversion Agent (including the Company if acting as the
Paying Agent or Conversion Agent), to the Holders of the particular Notes for the payment or settlement of which such monies or shares of Common Stock have been deposited with the Trustee, of all sums due and to become due thereon for principal and
Interest or the satisfaction of the Company’s conversion obligation, as the case may be, and payment of all other sums due under the Indenture. 
 Section 10.04. Paying Agent or Conversion Agent To Repay Monies and Shares Held. Upon the satisfaction and discharge of the Indenture, all monies and shares of Common Stock, if any, then held
by the Paying Agent or Conversion Agent (if other than the Trustee) shall, upon written request of the Company, be repaid or delivered to the Company or paid or delivered to the Trustee, and thereupon such Paying Agent or Conversion Agent shall be
released from all further liability with respect to such monies and shares of Common Stock, if any. 
 Subject to the
requirements of applicable law, any monies and shares of Common Stock deposited with or paid to the Trustee for payment of the principal of or Interest on or other obligations under, or to satisfy the Company’s conversion obligation with
respect to, the Notes and not applied but remaining unclaimed by the Holders of the Notes for two years after the date upon which the principal of or Interest on, or other obligations under, such Notes or the Company’s conversion obligation, as
the case may be, shall have become due and payable, shall be repaid or delivered to the Company by the Trustee on demand and all liability of the Trustee shall thereupon cease with respect to such monies and shares of Common Stock; and the Holder of
any of the Notes shall thereafter look only to the Company for any payment or delivery that such Holder may be entitled to collect unless an applicable abandoned property law designates another Person. 

Section 10.05. Reinstatement. If the Trustee or the Paying Agent or Conversion Agent is unable to apply any money or shares
of Common Stock in accordance with Section 10.03 by reason of any order or judgment of any court or governmental authority enjoining, restraining or otherwise prohibiting such application, the Company’s obligations under the Indenture and
the Notes shall be revived and reinstated as though no deposit had occurred pursuant to Section 10.02 until such time as the Trustee or the Paying Agent or Conversion Agent is permitted to apply all such money or shares of Common Stock in
accordance with Section 10.03; provided, however, that if the Company makes any payment of Interest on or principal of any Note or delivery of shares in respect of its conversion obligation following the reinstatement of
its obligations, the Company shall be subrogated to the rights of the Holders of such Notes to receive such payment from the money or shares of Common Stock held by the Trustee or Paying Agent or Conversion Agent. 

  
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 ARTICLE 11 

SUPPLEMENTAL INDENTURES 
 Section 11.01. Supplemental Indentures Without Consent of Holders. The Company and the Trustee at any time and from time to time may without notice to, or the consent of, any Holder enter into
one or more indentures supplemental hereto, in form satisfactory to the Trustee, for any of the following purposes in addition to the purposes set forth in Section 9.01 of the Original Indenture (as amended hereby with respect to the Notes):

 (i) to cure any ambiguity, omission, defect or inconsistency if such supplemental indenture does not adversely
affect Holders of the Notes; 
 (ii) to provide for the assumption by a successor corporation of the obligations
of the Company pursuant to Article 8 and otherwise comply with the provisions of Article 8; 
 (iii) to provide
that the Notes are convertible into Reference Property in accordance with Section 5.12 and effect any other changes to the terms of the Notes required under the Indenture in connection therewith; 

(iv) to make any change that does not adversely affect the rights of any Holder; or 

(v) to conform the provisions of the Indenture to the section entitled “Description of Debt Securities” in the
prospectus dated March 12, 2012, as supplemented and amended by the “Description of the Notes” section in the preliminary prospectus supplement dated March 12, 2012 and the related pricing term sheet dated March 13, 2012
relating to the offering and sale of the Notes, as evidenced in an Officer’s Certificate. 
 For purposes of the Notes,
clauses (a), (b), (e) and (f) of Section 9.01 of the Original Indenture shall be deemed to be deleted in their entirety. 
 Section 11.02. Supplemental Indentures with Consent of Holders. Except as provided below in this Section 11.02 and Section 9.02 of the Original Indenture, the Indenture or the Notes
may be amended as set forth in Section 9.02 of the Original Indenture. 
 Notwithstanding Section 9.02 of the Original
Indenture, and in addition to any restrictions set forth in the proviso in Section 9.02 of the Original Indenture, without the written consent of each Holder of an Outstanding Note affected thereby, no amendment, supplement or waiver may be
made to the Indenture if such amendment, supplement or waiver would: 
 (i) change the stated maturity of the
principal of the Notes; 
 (ii) reduce the amount of principal payable upon acceleration of the maturity of the
Notes; 

  
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 (iii) change the currency of payment of principal of or Interest on the
Notes or change any Note’s Place of Payment; 
 (iv) impair the right of any Holder to receive payment of
principal of and Interest on such Holder’s Notes on or after the due dates therefor or to institute suit for the enforcement of any payment on, or with respect to, the Notes; 

(v) modify the provisions with respect to the purchase rights of the Holders as provided in Article 4 or the provisions
with respect to the Company’s redemption right pursuant to Article 6, in each case, in a manner adverse to Holders of Notes; 
 (vi) change the ranking of the Notes; or 
 (vii) adversely affect
the right of Holders to convert their Notes hereunder, or reduce the Conversion Rate. 
 ARTICLE 12 

MISCELLANEOUS 
 Section 12.01. Provisions of Original Indenture. With respect to the Notes: 
 (i) Section 6.06 of the Original Indenture shall be amended by deleting the words “or subject the Trustee in its sole discretion to personal liability” in the first sentence thereof;

 (ii) Section 7.02(j) of the Original Indenture shall be amended by (a) inserting the word
“reasonable” immediately prior to the word “understanding” in the second sentence thereof and (b) inserting the word “reasonable” immediately prior to the word “reliance” in the third sentence thereof;

 (iii) Section 7.02 of the Original Indenture shall be amended by inserting the words “(including the
Fundamental Change Purchase Price or Redemption Price, if applicable) or the consideration due upon conversion of” immediately following the words “principal of” in the sentence following clause (k) thereof; and 

(iv) Section 7.14 of the Original Indenture shall be amended by (a) deleting the words “or, if later, after
it is known to a Responsible Officer of the Trustee or written notice of it is received by the Trustee” and (b) inserting the words “, or the consideration due upon conversion of,” following the words “or interest
on” in the proviso thereto. 
 Section 12.02. Successors. All agreements of the Company and the Trustee in the
Indenture and the Notes shall bind their respective successors. 
 Section 12.03. Multiple Originals. The parties
may sign any number of copies of this Supplemental Indenture. Each signed copy shall be an original, but all of them together 

  
 50 

 
represent the same agreement. One signed copy is enough to prove this Supplemental Indenture. The exchange of copies of this Indenture and of signature pages by facsimile or PDF transmission
shall constitute effective execution and delivery of this Indenture as to the parties hereto and may be used in lieu of the original Indenture for all purposes. Signatures of the parties hereto transmitted by facsimile or PDF shall be deemed to be
their original signatures for all purposes. 
 Section 12.04. Calculations. Except as otherwise provided herein, the
Company and its agents shall be responsible for making all calculations called for under the Indenture and the Notes, including, but not limited to, determinations of the Closing Sale Prices of Common Stock, any adjustments to the Conversion Rate,
the consideration deliverable in respect of any conversion and accrued Interest payable on the Notes. The Company shall make all these calculations in good faith and, absent manifest error, its calculations shall be final and binding on Holders. The
Company shall provide a schedule of its calculations to each of the Trustee and the Conversion Agent, and each of the Trustee and Conversion Agent is entitled to rely conclusively upon the accuracy of the Company’s calculations without
independent verification. The Trustee shall forward a copy of such schedule to any Holder upon the written request of such Holder. 
 Section 12.05. Benefits of Supplemental Indenture. Nothing in this Supplemental Indenture or in the Notes, express or implied, shall give to any Person, other than the parties hereto and their
respective successors hereunder and the Holders of Notes, any benefit or any legal or equitable right, remedy or claim under this Supplemental Indenture. 
 Section 12.06. Waiver of Jury Trial. EACH OF THE COMPANY AND THE TRUSTEE HEREBY IRREVOCABLY WAIVES, TO THE FULLEST EXTENT PERMITTED BY APPLICABLE LAW, ANY AND ALL RIGHT TO TRIAL BY JURY IN ANY
LEGAL PROCEEDING ARISING OUT OF OR RELATING TO THIS SUPPLEMENTAL INDENTURE, THE NOTES OR THE TRANSACTIONS CONTEMPLATED HEREBY OR THEREBY. 
 Section 12.07. Governing Law. THIS SUPPLEMENTAL INDENTURE SHALL BE DEEMED TO BE A CONTRACT MADE UNDER THE INTERNAL LAWS OF THE STATE OF NEW YORK, AND FOR ALL PURPOSES SHALL BE CONSTRUED IN
ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK, EXCEPT TO THE EXTENT THAT THE TRUST INDENTURE ACT IS APPLICABLE. 

[Remainder of the page intentionally left blank] 

  
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 IN WITNESS WHEREOF, the parties hereto have caused this Supplemental Indenture to be duly
executed as of the day and year first above written. 
  

			
	MEDIVATION, INC.
		
	By:	 	 /s/ C. Patrick Machado

	Name:	 	C. Patrick Machado
	Title:	 	Chief Business Officer and Chief Financial Officer
	
	WELLS FARGO BANK, NATIONAL ASSOCIATION, as Trustee
		
	By:	 	 /s/ Michael Tu

	Name:	 	Michael Tu
	Title:	 	Assistant Vice President

 SCHEDULE A 
 Make-Whole Table 
 The following table sets forth the number of Additional Shares to be
added to the Conversion Rate for each $1,000 principal amount of Notes pursuant to, and under the circumstances described in, Section 5.02 of this Supplemental Indenture, based on hypothetical Stock Prices and Effective Dates: 

 

																																																	
	 	  	Stock Price	 
	 Effective Date
	  	$	71.41	  	  	$	80.00	  	  	$	90.00	  	  	$	100.00	  	  	$	110.00	  	  	$	120.00	  	  	$	130.00	  	  	$	133.22	  	  	$	140.00	  	  	$	150.00	  	  	$	175.00	  	  	$	200.00	  
	 March 19, 2012
	  	 	4.2450	  	  	 	3.6285	  	  	 	2.9478	  	  	 	2.4357	  	  	 	2.0414	  	  	 	1.7320	  	  	 	1.4850	  	  	 	1.4162	  	  	 	1.2852	  	  	 	1.1215	  	  	 	0.8225	  	  	 	0.6255	  
	 April 1, 2013
	  	 	4.2450	  	  	 	3.5336	  	  	 	2.8132	  	  	 	2.2767	  	  	 	1.8684	  	  	 	1.5519	  	  	 	1.3029	  	  	 	1.2341	  	  	 	1.1044	  	  	 	0.9443	  	  	 	0.6601	  	  	 	0.4807	  
	 April 1, 2014
	  	 	4.2450	  	  	 	3.3251	  	  	 	2.5430	  	  	 	1.9687	  	  	 	1.5403	  	  	 	1.2169	  	  	 	0.9703	  	  	 	0.9038	  	  	 	0.7806	  	  	 	0.6335	  	  	 	0.3910	  	  	 	0.2555	  
	 April 1, 2015
	  	 	4.2450	  	  	 	3.1586	  	  	 	2.2503	  	  	 	1.5532	  	  	 	1.0073	  	  	 	0.5901	  	  	 	0.3016	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  
	 April 1, 2016
	  	 	4.2450	  	  	 	3.0502	  	  	 	2.1008	  	  	 	1.4019	  	  	 	0.8649	  	  	 	0.4219	  	  	 	0.0325	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  
	 April 1, 2017
	  	 	4.2450	  	  	 	2.7414	  	  	 	1.3525	  	  	 	0.2414	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  

 EXHIBIT A 
 [FORM OF FACE OF SECURITY] 
 [INCLUDE IF A GLOBAL SECURITY] 

[UNLESS THIS CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION (“DTC”), TO THE
COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC (AND ANY PAYMENT IS MADE
TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF,
CEDE & CO., HAS AN INTEREST HEREIN. 
 THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO,
AND IS REGISTERED IN THE NAME OF THE DEPOSITORY OR A NOMINEE OF THE DEPOSITORY. THIS SECURITY IS EXCHANGEABLE FOR SECURITIES REGISTERED IN THE NAME OF A PERSON OTHER THAN THE DEPOSITORY OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES DESCRIBED IN
THE INDENTURE, AND MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY, BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE OF THE DEPOSITARY OR BY THE DEPOSITARY OR ANY SUCH NOMINEE TO A
SUCCESSOR DEPOSITARY OR A NOMINEE OF SUCH SUCCESSOR DEPOSITARY.] 

  
 A-1

 MEDIVATION, INC. 
 Initially $[        ] 
 No.    

 2.625% Convertible Senior Note due 2017 
 CUSIP No.: 58501N AA9 
 ISIN Number: US58501NAA90 

MEDIVATION, INC., a Delaware corporation, promises to pay to [CEDE & CO., or its registered assigns]1, the principal sum of
             DOLLARS, [as revised by the Schedule of Increases or Decreases in Global Security attached hereto,]2 on April 1, 2017. 
 Interest Payment Dates: April 1 and October 1 (or, if any such day is not a Business Day, the immediately following Business Day) commencing on October 1, 2012. 

Interest Record Dates: March 15 and September 15. 
 Reference is made to the further provisions of this Note set forth on the reverse hereof, including, without limitation, provisions giving the Holder of this Note the right to convert this Note into cash,
shares of Common Stock or a combination thereof, at the Company’s election, on the terms and subject to the limitations referred to on the reverse hereof and as more fully specified in the Indenture. Such further provisions shall for all
purposes have the same effect as though fully set forth at this place. 
 In the case of any conflict between this Note and the
Indenture, the provisions of the Indenture shall control. 
 This Note shall not be valid or become obligatory for any purpose
until the certificate of authentication hereon shall have been manually signed by the Trustee or a duly authorized authenticating agent under the Indenture. 
  

 

	1 	 Use bracketed language for a Global Security. 

	2 	 Use bracketed language for a Global Security. 

  
 A-2

 IN WITNESS WHEREOF, the Company has caused this Note to be duly executed. 

 

			
	MEDIVATION, INC.
		
	By:	 	  

	Name:	 	
	Title:	 	

 TRUSTEE’S CERTIFICATE OF AUTHENTICATION 
 This is one of the Securities of the series designated herein issued under the within-mentioned Indenture. 
 WELLS FARGO BANK, NATIONAL 
 ASSOCIATION, as Trustee 

 

			
	By:	 	  

		 	Authorized Signatory

  

			
	 Dated:
	 	  

  
 A-3

 [FORM OF REVERSE OF NOTE] 

MEDIVATION, INC. 

2.625% Convertible Senior Note due 2017 
  

	1.	Interest 

 MEDIVATION,
INC., a Delaware corporation (such corporation, and its successors and assigns under the Indenture, the “Company”), promises to pay Interest on the principal amount of this Note at the rate of 2.625% per annum. The Company will
pay Interest semiannually on April 1 and October 1 of each year, commencing on October 1, 2012 (or, if any such day is not a Business Day, the immediately following Business Day). Interest on this Note will accrue from the most recent
date to which Interest has been paid or, if no Interest has been paid, from March 19, 2012. Interest will be computed on the basis of a 360-day year of twelve 30-day months. The Company shall pay Interest (including post-petition Interest in
any proceeding under any Bankruptcy Law) on overdue principal and premium, if any, from time to time on demand at the rate of Interest then in effect; and it shall pay Interest (including post-petition Interest in any proceeding under any Bankruptcy
Law) on overdue installments of Interest (without regard to any applicable grace periods) from time to time on demand at the same rate to the extent lawful. 
  

	2.	Paying Agent, Security Registrar and Conversion Agent 

 Initially, Wells Fargo Bank, National Association, a national banking association (the “Trustee”), will act as Paying Agent, Security Registrar and Conversion Agent. The Company may
appoint and change any Paying Agent, Security Registrar or Conversion Agent in accordance with the terms of the Indenture. The Company may act as Paying Agent, Security Registrar or Conversion Agent. 

 

	3.	Indenture 

 The Company
issued the Notes under an Indenture dated as of March 19, 2012 (the “Original Indenture”), as supplemented by the First Supplemental Indenture dated as of March 19, 2012 (the “Supplemental Indenture” and
the Original Indenture, as supplemented by the First Supplemental Indenture, the “Indenture”), between the Company and the Trustee. Terms defined in the Indenture and not defined herein have the meanings ascribed thereto in the
Indenture. The Notes are subject to all such terms, and Holders are referred to the Indenture for a statement of those terms. 

This Note is one of the Securities of the Company, designated as its 2.625% Convertible Senior Notes due 2017, issued pursuant to the
Indenture in an initial aggregate principal amount of $258,750,000. Additional Notes may be issued in accordance with the terms of the Indenture. The Indenture also imposes limitations on the ability of the Company to consolidate or merge with or
into any other Person or convey, transfer or lease all or substantially all of the property of the Company. 

  
 A-4

	4.	Conversion 

 Subject to
certain conditions and during certain periods specified in the Indenture, at any time until the close of business on the second Business Day immediately preceding the Stated Maturity Date of this Note, the Holder hereof has the right, at its option,
to convert each $1,000 principal amount of this Note into cash, shares of Common Stock or a combination of cash and shares of Common Stock, at the Company’s election, determined as set forth in the Indenture, based on the applicable Conversion
Rate, as the same may be adjusted from time to time pursuant to the terms of the Indenture. 
  

	5.	Denominations, Transfer, Exchange 

 The Notes are in registered form without coupons in denominations of $1,000 and whole multiples of $1,000. A Holder may transfer or exchange Notes in accordance with the terms of the Indenture, subject to
certain exceptions set forth therein. Upon any transfer or exchange, the Security Registrar and the Trustee may require a Holder, among other things, to furnish appropriate endorsements or transfer documents and to pay any taxes required by law or
permitted by the Indenture. 
  

	6.	Persons Deemed Owners 

The registered Holder of this Note may be treated as the owner of it for all purposes, subject to certain exceptions specified in the
Indenture. 
  

	7.	Defaults and Remedies 

 If
an Event of Default (other than an Event of Default relating to certain events of bankruptcy, insolvency or reorganization of the Company) occurs and is continuing, the Trustee or the Holders of at least 25% in principal amount of the Outstanding
Notes may declare the principal of and accrued and unpaid Interest on all the Notes to be due and payable. If an Event of Default relating to certain events of bankruptcy, insolvency or reorganization of the Company occurs, the principal of and
Interest on all the Notes will become immediately due and payable without any declaration or other act on the part of the Trustee or any Holder. Notwithstanding the foregoing, at the election of the Company, the sole remedy for an Event of Default
relating to a failure to file certain reports with the Commission and the Trustee shall for the first 365 calendar days after such Event of Default consist exclusively of the right to receive Additional Interest. 

 

	8.	No Recourse Against Others 

A director, officer, employee or stockholder, as such, of the Company shall not have any liability for any obligations of the Company
under the Notes or the Indenture or for any claim based on, in respect of or by reason of such obligations or their creation. By accepting a Note, each Holder waives and releases all such liability. The waiver and release are part of the
consideration for the issue of the Notes. 

  
 A-5

	9.	Authentication 

 This Note
shall not be valid until an authorized signatory of the Trustee (or an authenticating agent) manually signs the certificate of authentication on the other side of this Note. 

 

	10.	Abbreviations 

 Customary
abbreviations may be used in the name of a Holder or an assignee, such as TEN COM (=tenants in common), TEN ENT (=tenants by the entireties), JT TEN (=joint tenants with rights of survivorship and not as tenants in common), CUST (=custodian), and
U/G/M/A (=Uniform Gift to Minors Act). 
  

	11.	GOVERNING LAW 

 THIS NOTE
SHALL BE DEEMED TO BE A CONTRACT MADE UNDER THE INTERNAL LAWS OF THE STATE OF NEW YORK, AND FOR ALL PURPOSES SHALL BE CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK, EXCEPT TO THE EXTENT THAT THE TRUST INDENTURE ACT IS APPLICABLE.

  

	12.	CUSIP and ISIN Numbers 

The Company has caused CUSIP and ISIN numbers to be printed on the Notes and the Trustee shall use the CUSIP and ISIN numbers in notices
as a convenience to Holders, provided, that any such notice may state that no representation is made as to the correctness or accuracy of the CUSIP and ISIN numbers printed in the notice or on the Notes, and that reliance may be placed only
on the other identification numbers printed on the Notes, and that the validity of any such notice shall not be affected by any defect in or omission of any such numbers. 
 The Company will furnish to any Holder of Notes upon written request and without charge to the Holder a copy of the Indenture which has in it the text of this Note. 

  
 A-6

 SCHEDULE OF INCREASES AND DECREASES IN GLOBAL SECURITY3 

The following increases or decreases in this Global Security have been made: 

 

									
	 Date of Exchange
	 	 Amount of decrease in
principal amount of this
Global
Security
	 	 Amount of increase in

principal amount of this
 Global Security
	 	 Principal amount of this

Global Security

following such decrease
 or increase
	 	 Signature of

authorized

signatory of

Trustee or

Custodian

	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    

 

	3 	 For Global Securities only. 

  
 A-7

									
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        
	                    	 	                    	 	                    	 	                    	 	                    
	        	 	        	 	        	 	        	 	        

  
 A-8

 [FORM OF CONVERSION NOTICE] 
 To: Medivation, Inc. 
 The undersigned registered owner of this Note hereby
irrevocably exercises the option to convert this Note, or the portion thereof (which is $1,000 or a multiple thereof) below designated, into, cash, shares of Common Stock of Medivation, Inc. or a combination of cash and shares of Common Stock, at
the Company’s election, in accordance with the terms of the Indenture referred to in this Note, and directs that the check in payment for cash, if any, and the shares, if any, issuable and deliverable upon such conversion, together with any
check in payment for fractional shares and any Notes representing any unconverted principal amount hereof, be issued and delivered to the registered Holder hereof unless a different name has been indicated below. 

If shares or any portion of this Note not converted are to be issued in the name of a Person other than the undersigned, the undersigned
will provide the appropriate information below and pay all transfer taxes payable with respect thereto. In addition, subject to certain exceptions in the Indenture, if this notice is being delivered on a date after the close of business on a Record
Date and prior to the open of business on the related Interest Payment Date, this notice is accompanied by payment of an amount equal to the Interest payable on such Interest Payment Date of the principal of this Note to be converted. 

Capitalized terms used herein but not defined shall have the meanings ascribed to such terms in the Indenture. 

 

			
	Dated:	 	  

  

	
	  

	
	  

	Signature(s)
	
	Signature(s) must be guaranteed by an “eligible guarantor institution” meeting the requirements of the Registrar, which requirements include membership or participation in
the Security Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be determined by the Registrar in addition to, or in substitution for, STAMP, all in accordance with the Securities
Exchange Act of 1934, as amended.
	
	  

	Signature Guarantee

  
 A-9

 Fill in the registration of shares of Common Stock, if any, if to be issued, and Notes, if
any, to be delivered, and the person to whom cash, if any, and payment for fractional shares, if any, is to be made, if other than to and in the name of the registered Holder: 
 Please print name and address 
  

	
	  

	(Name)
	
	  

	(Street Address)
	
	  

	(City, State and Zip Code)
	
	Principal amount to be converted
	 (if less than all, must be $1,000 or whole multiples
thereof):

  

					
	 $
	 	  

  

	
	 Social Security or Other Taxpayer
Identification Number:

	  

 NOTICE: The signature on this Conversion Notice must correspond with the name as written upon the face of the Notes in
every particular without alteration or enlargement or any change whatever. 

  
 A-10

 [FORM OF FUNDAMENTAL CHANGE PURCHASE NOTICE] 

To: Medivation, Inc. 
 The undersigned
registered owner of this Note hereby acknowledges receipt of a notice from Medivation, Inc. (the “Company”) as to the occurrence of a Fundamental Change with respect to the Company and specifying the Fundamental Change Purchase Date
and requests and instructs the Company to purchase from the registered holder hereof in accordance with the applicable provisions of the Indenture referred to in this Note (1) the entire principal amount of this Note, or the portion thereof
(that is $1,000 principal amount or an integral multiple thereof) below designated, and (2) if such Fundamental Change Purchase Date does not fall during the period after a Record Date and on or prior to the corresponding Interest Payment Date,
accrued and unpaid Interest thereon to, but excluding, such Fundamental Change Purchase Date. 
 In the case of Physical Securities, the
certificate numbers of the Notes to be purchased are as set forth below: 
  

			
	Dated:	 	  

  

	
	  

	Signature(s)
	
	  

	Social Security or Other Taxpayer Identification Number
	
	principal amount to be repaid (if less than all): $            ,000
	
	NOTICE: The signature on the Fundamental Change Purchase Notice must correspond with the name as written upon the face of the Note in every particular without alteration or
enlargement or any change whatever.

  
 A-11

 [FORM OF ASSIGNMENT AND TRANSFER] 
 For value received
                                         
    hereby sell(s), assign(s) and transfer(s) unto                             
(Please insert social security or Taxpayer Identification Number of assignee) the within Note, and hereby irrevocably constitutes and appoints
                             attorney to transfer the said Note on the books of the Company, with full
power of substitution in the premises. 
  

			
	Dated:	 	  

  

	
	  

	
	  

	Signature(s)
	
	Signature(s) must be guaranteed by an institution which is a member of one of the following recognized signature Guarantee Programs:
	
	(i) The Securities Transfer Agent Medallion Program (STAMP); (ii) The New York Stock Exchange Medallion Program (MNSP); (iii) The Stock Exchange Medallion Program (SEMP)
or (iv) another guarantee program acceptable to the Trustee.
	
	  

	
	  

	Signature Guarantee

  
 B-1

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