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  Exhibit 10.8    
    

EPOCRATES, INC.
2008 EQUITY INCENTIVE PLAN

OPTION GRANT NOTICE  

        Epocrates, Inc. (the "Company"), pursuant to its 2008 Equity Incentive Plan (the
"Plan"), hereby grants to Optionholder an option to purchase the number of shares of the Company's Common Stock set forth below. This option is subject
to all of the terms and conditions as set forth herein and in the Option Agreement, the Plan, and the Notice of Exercise, all of which are attached hereto and incorporated herein in their entirety. 

 

 

			
	 Optionholder:
	 	 
	 	 	

  
	 Date of Grant:
	 	 
	 	 	

  
	 Vesting Commencement Date:
	 	 
	 	 	

  
	 Number of Shares Subject to Option:
	 	 
	 	 	

  
	 Exercise Price (Per Share):
	 	 
	 	 	

  
	 Total Exercise Price:
	 	 
	 	 	

  
	 Expiration Date:
	 	 
	 	 	

  

 

 

 

					
	Type of Grant:	 	o    Incentive Stock Option(1)
                        o    Nonstatutory Stock Option
	
 Exercise Schedule:	
 	
[Initial Grant: 1/4th of the shares vest and become exercisable one year after the Vesting Commencement Date; the balance of the shares vest and become exercisable in a series of thirty-six
(36) successive equal monthly installments measured from the first anniversary of the Vesting Commencement Date.]
	

 	
 	
[Refresher Grant: The shares vest and become exercisable in a series of forty-eight (48) successive equal monthly installments over the four (4)-year period measured from the Vesting Commencement Date.]
	
 Payment:	
 	
By one or a combination of the following items (described in the Option Agreement):
	

 	
 	
ý	
 	
By cash or check
	 	 	ý	 	Pursuant to a Regulation T Program if the Shares are publicly traded
	 	 	ý	 	By delivery of already-owned shares if the Shares are publicly traded

 

 Additional Terms/Acknowledgements:    The undersigned Optionholder acknowledges receipt of, and understands and agrees to, this Option Grant
Notice, the Option Agreement, and the Plan. Optionholder further acknowledges that as of the Date of Grant, this Option Grant Notice, the Option Agreement, and the Plan set forth the entire
understanding between Optionholder and the Company regarding the acquisition of stock in the Company and supersede all prior oral and written agreements on that subject with the exception of
(i) options previously granted and delivered to Optionholder under the Plan, and (ii) the following agreements only: 

 

 

			
	                OTHER AGREEMENTS:	 	 
	 	 	

  
	  	 	 
	 	 	

  

 

 

 

							
	 EPOCRATES, INC.	 	 OPTIONHOLDER:
	
 By:	
 	

 	
 	

 	
 	

 
	 	 	

  Signature	 	

  Signature
	Title:	 	 	 	Date:	 	 
	 	 	

  	 	 	 	

  
	Date:	 	 	 	 	 	 
	 	 	

  	 	 	 	 

 

 ATTACHMENTS:    Option Agreement, 2008 Equity Incentive Plan, and Notice of Exercise 

	(1)
	If
this is an Incentive Stock Option, it (plus other outstanding Incentive Stock Options) cannot be first  exercisable for more than $100,000 in value (measured by exercise price) in any calendar
year. Any excess over $100,000 is
a Nonstatutory Stock Option. 

 ATTACHMENT I

OPTION AGREEMENT

 

 
 

EPOCRATES, INC.
2008 EQUITY INCENTIVE PLAN    
    
    OPTION AGREEMENT
(INCENTIVE STOCK OPTION
OR NONSTATUTORY STOCK OPTION)    
    

        Pursuant to your Option Grant Notice ("Grant Notice") and this Option Agreement,
Epocrates, Inc. (the "Company") has granted you an option under its 2008 Equity Incentive Plan (the
"Plan") to purchase the number of shares of the Company's Common Stock indicated in your Grant Notice at the exercise price indicated in your Grant
Notice. Defined terms not explicitly defined in this Option Agreement but defined in the Plan shall have the same definitions as in the Plan. 

        The
details of your option are as follows: 

        1.    VESTING.    Subject to the limitations contained herein, your option will vest as
provided in your Grant Notice, provided that vesting will cease upon the termination of your Continuous Service. 

        2.    NUMBER OF SHARES AND EXERCISE PRICE.    The number of shares of Common Stock subject to
your option and your exercise price per share referenced in your Grant Notice may be adjusted from time to time for Capitalization Adjustments. 

        3.    EXERCISE RESTRICTION FOR NON-EXEMPT EMPLOYEES.    In the event that you are
an Employee eligible for overtime compensation under the Fair Labor Standards Act of 1938, as amended (i.e., a
"Non-Exempt Employee"), you may not exercise your option until you have completed at least six (6) months of Continuous Service
measured from the Date of Grant specified in your Grant Notice, notwithstanding any other provision of your option. 

        4.    METHOD OF PAYMENT.    Payment of the exercise price is due in full upon exercise of all
or any part of your option. You may elect to make payment of the exercise price in cash or by check or in one or more of the following manners: 

        (a)   Provided that at the time of exercise the Common Stock is publicly traded and quoted regularly in  The Wall Street Journal, pursuant to a program
developed under Regulation T as promulgated by the Federal Reserve Board that, prior to the
issuance of Common Stock, results in either the receipt of cash (or check) by the Company or the receipt of irrevocable instructions to pay the aggregate exercise price to the Company from the sales
proceeds. 

        (b)   Provided that at the time of exercise the Common Stock is publicly traded and quoted regularly in  The Wall Street Journal, by delivery to the
Company (either by actual delivery or attestation) of already-owned shares of Common Stock that are owned
free and clear of any liens, claims, encumbrances or security interests, and that are valued at Fair Market Value on the date of exercise. "Delivery" for these purposes, in the sole discretion of the
Company at the time you exercise your option, shall include delivery to the Company of your attestation of ownership of such shares of Common Stock in a form approved by the Company. Notwithstanding
the foregoing, you may not exercise your option by tender to the Company of Common Stock to the extent such tender would violate the provisions of any law, regulation or agreement restricting the
redemption of the Company's stock. 

        5.    WHOLE SHARES.    You may exercise your option only for whole shares of Common Stock. 

        6.    SECURITIES LAW COMPLIANCE.    Notwithstanding anything to the contrary contained herein,
you may not exercise your option unless the shares of Common Stock issuable upon such exercise are then registered under the Securities Act or, if such shares of Common Stock are not then so
registered, the Company has determined that such exercise and issuance would be exempt from the registration requirements of the Securities Act. The exercise of your option also must comply with other
applicable laws and regulations governing your option, and you may not exercise your option if the Company determines that such exercise would not be in material compliance with such laws and
regulations. 

        7.    TERM.    You may not exercise your option before the commencement or after the
expiration of its term. The term of your option commences on the Date of Grant and expires upon the earliest of the following: 

        (a)   immediately upon the termination of your Continuous Service for Cause; 

        (b)   three (3) months after the termination of your Continuous Service for any reason other than your Disability or
death; provided, however, that (i) if during any part of such three (3) month period your option is not exercisable solely because of the
condition set forth in Section 6, your option shall not expire until the earlier of the Expiration Date or until it shall have been exercisable for an aggregate period of three
(3) months after the termination of your Continuous Service and (ii) if (x) you are a Non-Exempt Employee, (y) you terminate your Continuous Service within six
(6) months after the Date of Grant specified in your Grant Notice, and (z) you have vested in a portion of your option at the time of your termination of Continuous Service, your option
shall not expire until the earlier of (A) the later of the date that is seven (7) months after the Date of Grant specified in your Grant Notice or the date that is three
(3) months after the termination of your Continuous Service, or (B) the Expiration Date; 

        (c)   twelve (12) months after the termination of your Continuous Service due to your Disability; 

        (d)   eighteen (18) months after your death if you die either during your Continuous Service or within three
(3) months after your Continuous Service terminates for any reason other than Cause; 

        (e)   the Expiration Date indicated in your Grant Notice; or 

        (f)    the day before the seventh (7th) anniversary of the Date of Grant. 

        If
your option is an Incentive Stock Option, note that to obtain the federal income tax advantages associated with an Incentive Stock Option, the Code requires that at all times
beginning on the date of grant of your option and ending on the day three (3) months before the date of your option's exercise, you must be an employee of the Company or an Affiliate, except in
the event of your death or Disability. The Company has provided for extended exercisability of your option under certain circumstances for your benefit but cannot guarantee that your option will
necessarily be treated as an Incentive Stock Option if you continue to provide services to the Company or an Affiliate as a Consultant or Director after your employment terminates or if you otherwise
exercise your option more than three (3) months after the date your employment with the Company or an Affiliate terminates. 

        8.    EXERCISE.    

        (a)   You may exercise the vested portion of your option during its term by delivering a Notice of Exercise (in a form
designated by the Company) together with the exercise price to the Secretary of the
Company, or to such other person as the Company may designate, during regular business hours, together with such additional documents as the Company may then require. 

        (b)   By exercising your option you agree that, as a condition to any exercise of your option, the Company may require you to
enter into an arrangement providing for the payment by you to the Company of any tax withholding obligation of the Company arising by reason of (i) the exercise of your option, or
(ii) the disposition of shares of Common Stock acquired upon such exercise. 

        (c)   If your option is an Incentive Stock Option, by exercising your option you agree that you will notify the Company in
writing within fifteen (15) days after the date of any disposition of any of the shares of the Common Stock issued upon exercise of your option that occurs within two (2) years after the
date of your option grant or within one (1) year after such shares of Common Stock are transferred upon exercise of your option. 

        9.    TRANSFERABILITY.    Your option is not transferable, except by will or by the laws of
descent and distribution, and is exercisable during your life only by you. Notwithstanding the foregoing, by delivering written notice to the Company, in a form satisfactory to the Company, you may
designate a 

third
party who, in the event of your death, shall thereafter be entitled to exercise your option. In addition, you may transfer your option to a trust if you are considered to be the sole beneficial
owner (determined under Section 671 of the Code and applicable state law) while the option is held in the trust, provided that you and the trustee enter into transfer and other agreements
required by the Company. 

        10.    OPTION NOT A SERVICE CONTRACT.    Your option is not an employment or service contract,
and nothing in your option shall be deemed to create in any way whatsoever any obligation on your part to continue in the employ of the Company or an Affiliate, or of the Company or an Affiliate to
continue your employment. In addition, nothing in your option shall obligate the Company or an Affiliate, their respective stockholders, Boards of Directors, Officers or Employees to continue any
relationship that you might have as a Director or Consultant for the Company or an Affiliate. 

        11.    WITHHOLDING OBLIGATIONS.    

        (a)   At the time you exercise your option, in whole or in part, or at any time thereafter as requested by the Company, you
hereby authorize withholding from payroll and any other amounts payable to you, and otherwise agree to make adequate provision for (including by means of a "cashless exercise" pursuant to a program
developed under Regulation T as promulgated by the Federal Reserve Board to
the extent permitted by the Company), any sums required to satisfy the federal, state, local and foreign tax withholding obligations of the Company or an Affiliate, if any, which arise in connection
with the exercise of your option. 

        (b)   Upon your request and subject to approval by the Company, in its sole discretion, and compliance with any applicable
legal conditions or restrictions, the Company may withhold from fully vested shares of Common Stock otherwise issuable to you upon the exercise of your option a number of whole shares of Common Stock
having a Fair Market Value, determined by the Company as of the date of exercise, not in excess of the minimum amount required to be withheld by law (or such lower amount as may be necessary to avoid
classification of your option as a liability for financial accounting purposes). Any adverse consequences to you arising in connection with such share withholding procedure shall be your sole
responsibility. 

        (c)   You may not exercise your option unless the tax withholding obligations of the Company and/or any Affiliate are
satisfied. Accordingly, you may not be able to exercise your option when desired even though your option is vested, and the Company shall have no obligation to issue a certificate for such shares of
Common Stock or release such shares of Common Stock from any escrow provided for herein unless such obligations are satisfied. 

        12.    NOTICES.    Any notices provided for in your option or the Plan shall be given in
writing and shall be deemed effectively given upon receipt or, in the case of notices delivered by mail by the Company to you, five (5) days after deposit in the United States mail, postage
prepaid, addressed to you at the last address you provided to the Company. 

        13.    GOVERNING PLAN DOCUMENT.    Your option is subject to all the provisions of the Plan,
the provisions of which are hereby made a part of your option, and is further subject to all interpretations, amendments, rules and regulations, which may from time to time be promulgated and adopted
pursuant to the Plan. In the event of any conflict between the provisions of your option and those of the Plan, the provisions of the Plan shall control. 

 ATTACHMENT II  

 2008 EQUITY INCENTIVE PLAN  

 ATTACHMENT III  

 NOTICE OF EXERCISE  

 NOTICE OF EXERCISE  

 

 

					
	 	 	 	 	

  
	 	 	 	 	

  
	Epocrates, Inc.

1100 Park Place, Suite 300

San Mateo, CA 94403	 	 Date of Exercise:	 	 
	 	 	 	 	

  

 

 Ladies
and Gentlemen: 

        This
constitutes notice under my stock option that I elect to purchase the number of shares for the price set forth below. 

 

 

							
	Type of option (check one):	 	o Incentive	 	 o Nonstatutory
	
Stock option dated:	
 	

 	
 	

 	
 	

 
	 	 	 	 	 
	
Number of shares as to which option is exercised:	
 	

 	
 	

 	
 	

 
	 	 	 	 	 
	
Certificates to be issued in name of:	
 	

 	
 	

 	
 	

 
	 	 	 	 	 
	
Total exercise price:	
 	
 $	
 	

 	
 	

 
	 	 	 	 	 	 	 
	
Cash payment delivered herewith:	
 	
 $	
 	

 	
 	

 
	 	 	 	 	 	 	 
	
Value of                          shares of Epocrates, Inc. Common Stock
delivered herewith(2):	
 	
 $	
 	

 	
 	

 
	 	 	 	 	 	 	 

 

         By
this exercise, I agree (i) to provide such additional documents as you may require pursuant to the terms of the Epocrates, Inc. 2008 Equity Incentive Plan,
(ii) to provide for the payment by me to you (in the manner designated by you) of your withholding obligation, if any, relating to the exercise of this option, and (iii) if this exercise
relates to an incentive stock option, to notify you in writing within fifteen (15) days after the date of any disposition of any of the shares of Common Stock issued upon exercise of this
option that occurs within two (2) years after the date of grant of this option or within one (1) year after such shares of Common Stock are issued upon exercise of this option. 

 

 

			
	 	 	Very truly yours,
	

 	
 	
  

 

 

 

	(2)
	Shares
must meet the public trading requirements set forth in the option. Shares must be valued on the date of exercise in accordance with the terms of the
Plan and the option being exercised, and must be owned free and clear of any liens, claims, encumbrances or security interests. Certificates must be endorsed or accompanied by an executed assignment
separate from certificate. 

QuickLinks

Exhibit 10.8

EPOCRATES, INC. 2008 EQUITY INCENTIVE PLAN OPTION AGREEMENT (INCENTIVE STOCK OPTION OR NONSTATUTORY STOCK OPTION)QuickLinks
 -- Click here to rapidly navigate through this document

 

 
 

  Exhibit 10.9    
    

 
  EPOCRATES, INC.
  2008 EQUITY INCENTIVE PLAN    
    
    OPTION GRANT NOTICE    
    

        Epocrates, Inc. (the "Company"), pursuant to its 2008 Equity Incentive Plan (the
"Plan"), hereby grants to Optionholder an option to purchase the number of shares of the Company's Common Stock set forth below. This option is subject
to all of the terms and conditions as set forth herein and in the Option Agreement, the Plan, and the Notice of Exercise, all of which are attached hereto and incorporated herein in their entirety. 

 

 

			
	 Optionholder:
	 	

 
	 Date of Grant:
	 	

 
	 Vesting Commencement Date:
	 	

 
	 Number of Shares Subject to Option:
	 	

 
	 Exercise Price (Per Share):
	 	

 
	 Total Exercise Price:
	 	

 
	 Expiration Date:
	 	

 

 

 Type of Grant(1)(2)  

  

	(1)
	The first            shares subject to the option is an Incentive Stock Option. The
remaining            shares subject to
the option is a nonstatutory stock option. In the event shares subject to the option are not vested as part of the Initial Vesting (as such term is defined in Schedule A), the shares subject to
the nonstatutory stock option shall revert to and again become available for issuance under the Plan.

	(2)
	An
Incentive Stock Option may not be exercised by a net exercise arrangement. 

 

  

					
	Exercise Schedule:	 	Same as Vesting Schedule.
	
 Vesting Schedule:	
 	
Shares subject to the Option shall vest in accordance with the terms set forth on Schedule A.
	
 Payment:	
 	
By one or a combination of the following items (described in the Option Agreement):
	

 	
 	
 ý	
 	
 By cash or check
	 	 	 ý	 	 Pursuant to a Regulation T Program if the Shares are publicly traded
	 	 	 ý	 	 By delivery of already-owned shares if the Shares are publicly traded
	 	 	 ý	 	 By net exercise, if the Company has established procedures for net exercise(2)

 

          Additional Terms/Acknowledgements:    The undersigned Optionholder acknowledges receipt of, and understands and agrees to, this Option
Grant Notice, the
Option Agreement, and the Plan. Optionholder further acknowledges that as of the Date of Grant, this Option Grant Notice, the Option Agreement, and the Plan set forth the entire understanding between
Optionholder and the Company regarding the acquisition of stock in the Company and supersede all prior oral and written agreements 

on
that subject with the exception of (i) options previously granted and delivered to Optionholder under the Plan, and (ii) the following agreements only: 

 

 

			
	 OTHER AGREEMENTS:
	 	 None

	 	 	 

 
	

 	
 	

 

 

 

 

 

							
	  EPOCRATES, INC.
	 	 OPTIONHOLDER

	 By:
	 	 

 	 	 

 
	 
	 	 Signature
	 	 Signature

	 Title:
	 	 

 	 	 Date:
	 	 

 
	 Date:
	 	 

 	 	 	 	 

 

 ATTACHMENTS:    Option Agreement, 2008 Equity Incentive Plan and Notice of Exercise 

 

 
 

SCHEDULE A
OPTIONHOLDER
PERFORMANCE-BASED STOCK OPTION GRANT NOTICE    
    

 

 

					
	Shares subject to Performance Based Option

 
	 	100% Payout 	 	125% Payout 
	 2009 Bookings
	 	[            ]	 	[            ]
	 2009 Revenue
	 	[            ]	 	[            ]
	 Modified EBITDA
	 	[            ]	 	[            ]
	 	 	 	 	 
	 Total
	 	 [            ]	 	[            ]

 

         The
Epocrates, Inc. (the "Company") 2009 bookings ("Bookings"), 2009 revenue
("Revenue") and earnings before interests, taxes, depreciation and amortization, as adjusted for certain non-cash items in accordance with
the Company's business plan and as determined by the Audit Committee of the Board ("Modified EBITDA") (together, the
"Metrics") goals are as set forth below on Table A below: 

 
 

  Table A    
    

 

 

																								
	BOOKINGS	 	REVENUE	 	MODIFIED EBITDA	 
	% of Plan 	 	2009 Plan

(in 000s) 	 	Payout

% 	 	% of

Plan 	 	2009 Plan

(in 000s) 	 	Payout

% 	 	% of

Plan 	 	2009 Plan

(in 000s) 	 	Payout

% 	 
	 £ 75%
	 	 	77,471	 	 	0	%	 £ 90%
	 	 	90,910	 	 	0	%	 £ 70%
	 	 	15,688	 	 	0	%
	 £ 90%
	 	 	92,966	 	 	75	%	 £ 95%
	 	 	95,960	 	 	75	%	 £ 85%
	 	 	19,049	 	 	75	%
	 100%
	 	 	103,295	 	 	100	%	 100%
	 	 	101,011	 	 	100	%	 100%
	 	 	22,411	 	 	100	%
	 3 105%
	 	 	108,460	 	 	125	%	 3 105%
	 	 	106,062	 	 	125	%	 3 115%
	 	 	25,773	 	 	125	%

 

         On
the date the 2009 financial results for the Company are available and the Compensation Committee of the Board determines, in its sole discretion, the percentage of plan achieved by
the Company for each of the Metrics (the "Payout Determination Date"), the corresponding number of shares ("Milestone
Shares") in connection with each of the Metrics prorated in the event performance falls between points on Table A, and rounded to the nearest whole number, will commence
vesting. Each of the above Metrics will be assigned equal weight in determining the Milestone Shares. The Milestone Shares shall be subject to vesting at the rate of 1/36th of the
Milestone Shares per month commencing on January 1, 2010 (the "Vesting Commencement Date"); provided,
however, that vesting will cease upon the termination of Optionholder's Continuous Service. For the avoidance of doubt, any shares that would have vested in connection with
this vesting schedule between the Vesting Commencement Date and the Payout Determination Date will first vest on the Payout Determination Date. The balance of the shares granted but not included in
the Milestone Shares shall revert to and again become available for issuance under the 2008 Equity Incentive Plan. Further, no shares subject to the Option are exercisable until the Payout
Determination Date. 

        For
example, in order for Optionholder to achieve vesting of the number of shares specified at the 100% Payout level in the table above, the Company must achieve 100% of plan for
Bookings, Revenue and Modified EBITDA, such that [            ] Milestone Shares will commence vesting for each of Bookings, Revenue and Modified EBITDA on the Payout
Determination Date. The Milestone Shares shall be subject to continued vesting at the rate of 1/36th of the Milestone Shares per month commencing effective on the Vesting
Commencement Date. The balance of the shares not included in the Milestone Shares shall revert to and again become available for issuance under the 2008 Equity Incentive Plan. 

        In
the event, the Company achieves 75% of plan or less for Bookings, 90% of plan or less for Revenue and 70% of plan or less for Modified EBITDA, the Optionholder will not vest any of
the shares for any of the Metrics, no shares will vest on the Payout Determination Date and all the Shares shall revert to and again become available for issuance under the 2008 Equity Incentive Plan. 

        Similarly,
in the event the Company achieves 105% of plan or greater for Bookings and Revenue and 115% of plan or greater for Modified EBITDA, the Optionholder will commence vesting as
to 

125%
of [            ] Milestone Shares for each of Bookings, Revenue and Modified EBITDA such that an aggregate of [            ]
Milestone
Shares will commence vesting on the Payout Determination Date. Such Milestone Shares shall be subject to continued vesting at the rate of 1/36th of the Milestone Shares per month
commencing effective on the Vesting Commencement Date. 

QuickLinks

Exhibit 10.9

EPOCRATES, INC. 2008 EQUITY INCENTIVE PLAN OPTION GRANT NOTICE

SCHEDULE A OPTIONHOLDER PERFORMANCE-BASED STOCK OPTION GRANT NOTICE

Table A

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