Document:

EX-4.3

 

Exhibit
4.3
Conformed Copy
EXECUTION COPY

     SIXTH SUPPLEMENTAL INDENTURE, dated as of November 14, 2005 (this “Sixth Supplemental
Indenture”), between WYETH (as successor to AMERICAN HOME PRODUCTS CORPORATION), a Delaware
corporation (the “Issuer”) and JPMORGAN CHASE BANK, N.A. (as successor to MANUFACTURERS
HANOVER TRUST COMPANY), as trustee (the “Trustee”).

W I T N E S S E T H

     WHEREAS, the Issuer and the Trustee have duly executed and delivered an Indenture, dated as of
April 10, 1992 (as amended on October 13, 1992, the “Indenture”), providing for the
authentication, issuance, delivery and administration of unsecured debentures, notes or other
evidences of indebtedness to be issued in one or more series by the Issuer (the
“Securities”);

     WHEREAS, pursuant to the terms of the Indenture, the Issuer desires to provide for the
establishment of new series of Securities (the “Notes”) to be issued under the Indenture in
an aggregate principal amount of up to $1,500,000,000, which may be authenticated and delivered as
provided in the Indenture;

     WHEREAS, the Issuer desires to amend the provisions of the Indenture to issue the Notes under
the terms of the Indenture as supplemented hereby;

     WHEREAS, Section 8.1 of the Indenture expressly permits the Issuer and the Trustee to enter
into one or more supplemental indentures for the purposes, inter alia, of establishing the forms
and terms of Securities to be issued under the Indenture or making certain provisions in the
Indenture which the Issuer deems necessary or desirable, and permits the execution of such
supplemental indentures without the consent of the Holders of any Securities then outstanding;

     WHEREAS, for the purposes hereinabove recited, and pursuant to due corporate action, the
Issuer has duly determined to execute and deliver to the Trustee this Sixth Supplemental Indenture;
and

     WHEREAS, all conditions and requirements necessary to make this Sixth Supplemental Indenture a
valid, legal and binding instrument in accordance with its terms have been done and performed, and
the execution and delivery hereof have been in all respects duly authorized;

     NOW, THEREFORE, in consideration of the premises, the Issuer and the Trustee mutually covenant
and agree as follows:

     SECTION 1. DEFINITIONS.

     1.1 All terms contained in this Sixth Supplemental Indenture shall, except as
specifically provided herein or except as the context may otherwise require, have the meanings
given to such terms in the Indenture.

 

 

     1.2 Unless the context otherwise requires, the following terms shall have the following
meanings:

     “Applicable Procedures” means, with respect to any transfer or exchange of or for
beneficial interests in any Global Note, the rules and procedures of the Depositary that apply to
such transfer or exchange.

     “Depositary” means The Depository Trust Company or any other depositary from time to
time specified pursuant to the Indenture.

     “Definitive Note” means a certificated Note registered in the name of the Holder
thereof and issued in accordance with Section 4 hereof, substantially in the form of Exhibit A
hereto except that such Note shall not bear the Global Note Legend and shall not have the “Schedule
of Exchanges of Interests in the Global Note” attached thereto.

     “Exchange Notes” has the meaning set forth in the Registration Rights Agreement.

     “Exchange Offer” has the meaning set forth in the Registration Rights Agreement.

     “Exchange Offer Registration Statement” has the meaning set forth in the Registration
Rights Agreement.

     “Global Note Legend” means the legend set forth in Section 4.7(b) which is required to
be placed on all Global Notes issued under this Sixth Supplemental Indenture.

     “Global Notes” means, individually and collectively, each of the Restricted Global
Notes and the Unrestricted Global Notes, substantially in the form of Exhibit A hereto that bears
the Global Note Legend and that has the “Schedule of Exchanges of Interests in the Global Note”
attached thereto, issued in accordance with Section 4.2(d), 4.4(b) or 4.6 hereof.

     “Indirect Participant” means a person who holds a beneficial interest in a Global Note
through a Participant.

     “Initial Purchasers” has the meaning set forth in the Purchase Agreement dated as of
November 8, 2005, by and among the Issuer, J.P. Morgan Securities Inc. and Citigroup Global Markets
Inc. (as representatives of the several Initial Purchasers).

     “Letter of Transmittal” means the letter of transmittal to be prepared by the Issuer
and sent to all Holders of the Notes for use by such Holders in connection with the Exchange Offer.

     “Non-U.S. Person” means any person that is not a U.S. person as defined in Rule 902(o)
under the Securities Act.

     “Notes” means the 5.50% Notes due 2016 and the 6.00% Notes due 2036 as those notes are
defined in Sections 2.1 and 2.2, respectively.

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     “Offshore Global Note” means a Global Note that initially bears the Temporary Offshore
Global Note Legend pursuant to section 3.2 hereof, originally issued and sold pursuant to
Regulation S.

     “Participant” means a person who has an account with the Depositary.

     “Participating Broker-Dealer” has the meaning set forth in the Registration Rights
Agreement.

     “Private Exchange” has the meaning set forth in the Registration Rights Agreement.

     “Private Exchange Notes” has the meaning set forth in the Registration Rights
Agreement.

     “Private Placement Legend” means the legend set forth in Section 4.7(a) to be placed
on all Notes issued under this Sixth Supplemental Indenture except where otherwise permitted by the
provisions of this Sixth Supplemental Indenture.

     “QIB” means a “qualified institutional buyer” as defined in Rule l44A.

     “Registrar” means the registrar specified from time to time pursuant to Section 3.2 of
the Indenture.

     “Registration Rights Agreement” means the Exchange and Registration Rights Agreement,
dated as of the date hereof, by and among the Issuer, J.P. Morgan Securities Inc. and Citigroup
Global Markets Inc. (as representatives of the several initial purchasers listed therein), as such
agreement may be amended, modified or supplemented from time to time.

     “Regulation S” means Regulation S under the Securities Act.

     “Restricted Definitive Note” means a Definitive Note bearing the Private Placement
Legend.

     “Restricted Global Note” means a Global Note bearing the Private Placement Legend.

     “Restricted Period” means the relevant 40-day distribution compliance period as
defined and provided in Regulation S.

     “Ru1e144” means Rule 144 promulgated under the Securities Act.

     “Rule 144A” means Rule 144A promulgated under the Securities Act.

     “Securities Act” means the Securities Act of 1933, as amended.

     “Shelf Registration Statement” has the meaning set forth in the Registration Rights
Agreement.

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     “Temporary Offshore Global Note Legend” means the legend set forth in Section 4.7(c).

     “Unrestricted Definitive Note” means one or more Definitive Notes that do not bear
and, pursuant to Section 4.7, are not required to bear the Private Placement Legend.

     “Unrestricted Global Note” means one or more Global Notes that do not bear and,
pursuant to Section 4.7, are not required to bear the Private Placement Legend.

     SECTION 2. TERMS AND CONDITIONS OF THE SECURITIES.

     There is hereby authorized the following series of Notes:

     2.1 5.50% Notes due 2016.

          (a) Two series of senior unsecured notes (collectively, the “5.50% Notes due 2016”) are hereby
authorized and designated as the “5.50% Series A Notes due 2016” and the “5.50% Series B Notes due
2016”.

          (b) The 5.50% Notes due 2016 shall be limited in aggregate principal amount to $1,000,000,000,
shall bear interest at a rate of 5.50% per annum, shall mature on February 15, 2016 and shall be
subject to optional redemption at any time by the Issuer pursuant to the terms set forth in the
form of Note with respect thereto.

          (c) The 5.50% Series A Notes due 2016 and the 5.50% Series B Notes due 2016 shall be identical
in all material respects except that the (i) 5.50% Series A Notes due 2016 and any 5.50% Series B
Notes due 2016 issued in the Private Exchange shall be issued bearing the Private Placement Legend
and (ii) 5.50% Series B Notes due 2016 issued pursuant to the Exchange Offer shall be issued
without bearing the Private Placement Legend. It is intended that the 5.50% Series A Notes due
2016 will be exchanged for the 5.50% Series B Notes due 2016 pursuant to Section 4.6 hereof.

     2.2 6.00% Notes due 2036.

          (a) Two series of senior unsecured notes (collectively, the “6.00% Notes due 2036”) are hereby
authorized and designated as the “6.00% Series A Notes due 2036” and the “6.00% Series B Notes due
2036”.

          (b) The 6.00% Notes due 2036 shall be limited in aggregate principal amount to $500,000,000,
shall bear interest at a rate of 6.00% per annum, shall mature on February 15, 2016 and shall be
subject to optional redemption at any time by the Issuer pursuant to the terms set forth in the
form of Note with respect thereto.

          (c) The 6.00% Series A Notes due 2036 and the 6.00% Series B Notes due 2036 shall be identical
in all material respects except that the (i) 6.00% Series A Notes due 2036 and any 6.00% Series B
Notes due 2036 issued in the Private Exchange shall be issued bearing the Private Placement Legend
and (ii) 6.00% Series B Notes due 2036 issued pursuant to the Exchange Offer shall be issued
without bearing the Private

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Placement Legend. It is intended that the 6.00% Series A Notes due 2036 will be exchanged for
the 6.00% Series B Notes due 2036 pursuant to Section 4.6 hereof.

     2.3 Issuance of Additional Securities. The Issuer shall be permitted to amend this
Sixth Supplemental Indenture in order to increase the aggregate principal amount of Notes of any
series that may be issued hereunder without the consent of the Holders of Notes of any series so
affected.

     SECTION 3. FORM OF NOTES.

     3.1 Form of Global Notes. The Notes shall be issued in the form of Global Notes
(including the Global Note Legend thereon and the “Schedule of Exchanges of Interests in the Global
Note” attached thereto and, in the case of Offshore Global Notes, initially including the Temporary
Offshore Global Note Legend). Each Global Note shall represent such of the outstanding Notes as
shall be specified therein and each shall provide that it shall represent the aggregate principal
amount of outstanding Notes from time to time endorsed thereon and that the aggregate principal
amount of outstanding Notes represented thereby may from time to time be reduced or increased, as
appropriate, to reflect exchanges and redemptions. Any endorsement of a Global Note to reflect the
amount of any increase or decrease in the aggregate principal amount of outstanding Notes
represented thereby shall be made by the Trustee, as custodian of the Global Notes, in accordance
with instructions given by the Holder thereof as required by Sections 3.2 and 4 hereof.

     3.2 Offshore Global Notes.

          (a) Each Note originally sold by the Initial Purchasers in reliance upon Regulation S will be
evidenced by one or more Offshore Global Notes bearing the Temporary Offshore Global Note Legend
and subject to the restrictions set forth in such Temporary Offshore Global Note Legend.

          (b) Upon expiration of the Restricted Period, the Temporary Offshore Global Note Legend will
be removed from each Offshore Global Note.

          (c) Notwithstanding any provisions to the contrary in this Sixth Supplemental Indenture,
Offshore Global Notes shall be treated as Global Notes in the application of all provisions of the
Indenture and this Sixth Supplemental Indenture, except in the application of the provisions of
this Section 3.2 and Section 4.7(c) hereof.

     SECTION 4. TRANSFER AND EXCHANGE.

     Notwithstanding any provisions to the contrary set forth in Article Two of the Indenture,
the following terms and conditions shall govern the transfer and exchange of the Notes.

     4.1 Transfer and Exchange of Global Notes. A Global Note may not be transferred as a
whole except by the Depositary to a nominee of the Depositary, by a

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nominee of the Depositary to the Depositary or to another nominee of the Depositary, the
Depositary or any such nominee to a successor Depositary or a nominee of such successor Depositary.
All Global Notes will be exchanged by the Issuer for Definitive Notes if (i) the Issuer delivers
to the Trustee notice from the Depositary that it is unwilling or unable to continue to act as
Depositary or that it is no longer a clearing agency registered under the Exchange Act and, in
either case, a successor Depositary is not appointed by the Issuer within 90 days after the date of
such notice from the Depositary, (ii) the Issuer in its sole discretion determines that the Global
Notes (in whole but not in part) should be exchanged for individual Notes and delivers a written
notice to such effect to the Trustee or (iii) an Event of Default shall have occurred and be
continuing with respect to the Notes. Upon the occurrence of any of the preceding events in (i),
(ii) or (iii) above, Definitive Notes shall be issued in such names as the Depositary shall
instruct the Trustee. Every Note authenticated and delivered in exchange for, or in lieu of, a
Global Note or any portion thereof, pursuant to this Section 4 hereof, shall be authenticated and
delivered in the form of, and shall be, a Global Note. A Global Note may not be exchanged for
another Note other than as provided in this Section 4, however, beneficial interests in a Global
Note may be transferred and exchanged as provided in Section 4.2, 4.3 or 4.6 hereof.

     4.2 Transfer and Exchange of Beneficial Interests in the Global Notes. The transfer
and exchange of beneficial interests in the Global Notes shall be effected through the Depositary,
in accordance with the provisions of the Indenture, as supplemented by this Sixth Supplemental
Indenture, and the Applicable Procedures. Beneficial interests in any Restricted Global Note
bearing the Private Placement Legend shall be subject to restrictions on transfer comparable to
those set forth herein to the extent required by the Securities Act. Transfers of beneficial
interests in the Global Notes also shall require compliance with either subparagraph (a) or (b)
below, as applicable, as well as one or more of the other following subparagraphs, as applicable:

          (a) Transfer of Beneficial Interests in the Same Global Note. Beneficial interests in any
Restricted Global Note may be transferred to persons who take delivery thereof in the form of a
beneficial interest in the same Restricted Global Note in accordance with the transfer restrictions
set forth in the Private Placement Legend. Beneficial interests in any Unrestricted Global Note
may be transferred to persons who take delivery thereof in the form of a beneficial interest in an
Unrestricted Global Note. No written orders or instructions shall be required to be delivered to
the Registrar to register the transfers described in this Section 4.2(a).

          (b) All Other Transfers and Exchanges of Beneficial Interests in Global Notes. In connection
with all transfers and exchanges of beneficial interests that are not subject to Section 4.2(a)
above, the transferor of such beneficial interest must deliver to the Depositary either (1) (A) a
written order from a Participant or an Indirect Participant given to the Depositary in accordance
with the Applicable Procedures directing the Depositary to credit or cause to be credited a
beneficial interest in the Global Note, or in another Global Note in the case of an exchange, in an
amount equal to the beneficial interest to be transferred or exchanged and (B) instructions given
in accordance with the Applicable Procedures containing information regarding the Participant
account to be credited with such increase or (2) (A) a written order from a Participant or an
Indirect Participant given

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to the Depositary in accordance with the Applicable Procedures directing the Depositary to
cause to be issued a Definitive Note in an amount equal to the beneficial interest to be
transferred or exchanged and (B) instructions given by the Depositary to the Registrar containing
information regarding the person in whose name such Definitive Note shall be registered to effect
the transfer or exchange referred to in (A) above. Upon consummation of an Exchange Offer by the
Issuer in accordance with Section 4.6 hereof, the requirements of this Section 4.2(b) shall be
deemed to have been satisfied upon receipt by the Registrar of the instructions contained in the
Letter of Transmittal delivered by the holder of such beneficial interests in the Restricted Global
Notes. Upon satisfaction of all of the requirements for transfer or exchange of beneficial
interests in Global Notes contained in the Indenture, as supplemented by this Sixth Supplemental
Indenture, and the Notes or otherwise applicable under the Securities Act, the Trustee shall adjust
the principal amount of the relevant Global Note(s) pursuant to Section 4.8 hereof.

          (c) Transfer of Beneficial Interests to Another Restricted Global Note. A beneficial interest
in any Restricted Global Note may be transferred to a person who takes delivery thereof in the form
of a beneficial interest in another Restricted Global Note if the transfer complies with the
requirements of Section 4.2(b) above and the transferor delivers a certificate in the form of
Exhibit B hereto, including the certifications in item (1) thereof.

          (d) Transfer and Exchange of Beneficial Interests in a Restricted Global Note for Beneficial
Interests in the Unrestricted Global Note. A beneficial interest in any Restricted Global Note may
be exchanged by any holder thereof for a beneficial interest in an Unrestricted Global Note or
transferred to a person who takes delivery thereof in the form of a beneficial interest in an
Unrestricted Global Note if the exchange or transfer complies with the requirements of Section
4.2(b) above and:

     (i) such exchange or transfer is effected pursuant to the Exchange Offer in accordance
with the Registration Rights Agreement and the holder of the beneficial interest to be
transferred, in the case of an exchange, or the transferee, in the case of a transfer,
certifies in the applicable Letter of Transmittal or via the Depositary’s book-entry system
that it is not (A) a broker-dealer, (B) a person participating in the distribution of the
Exchange Notes or (C) a person who is an affiliate (as defined in Rule 144) of the Issuer;
or

     (ii) such transfer is effected pursuant to the Shelf Registration Statement in
accordance with the Registration Rights Agreement; or

     (iii) such transfer is effected by a Participating Broker-Dealer pursuant to the
Exchange Offer Registration Statement in accordance with the Registration Rights Agreement;
or

     (iv) the Registrar receives the following:

     (A) if the holder of such beneficial interest in a Restricted Global Note
proposes to exchange such beneficial interest for a beneficial

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interest in an Unrestricted Global Note, a certificate from such holder in the
form of Exhibit C hereto, including the certifications in item (1 )(a) thereof; or

     (B) if the holder of such beneficial interest in a Restricted Global Note
proposes to transfer such beneficial interest to a person who shall take delivery
thereof in the form of a beneficial interest in an Unrestricted Global Note, a
certificate from such holder in the form of Exhibit B hereto, including the
certifications in item (4) thereof;

and, in each such case set forth in this subparagraph (iv), if the Registrar so requests or if the
Applicable Procedures so require, an Opinion of Counsel in form reasonably acceptable to the
Registrar to the effect that such exchange or transfer is in compliance with the Securities Act and
that the restrictions on transfer contained herein and in the Private Placement Legend are no
longer required in order to maintain compliance with the Securities Act.

     If any such transfer is effected pursuant to subparagraph (ii) or (iv) above at a time when an
Unrestricted Global Note has not yet been issued, the Issuer shall issue and, upon receipt of an
Issuer Order in accordance with Section 2.4 of the Indenture, the Trustee shall authenticate one or
more Unrestricted Global Notes in an aggregate principal amount equal to the aggregate principal
amount of beneficial interests transferred pursuant to subparagraph (ii) or (iv) above.

     Beneficial interests in an Unrestricted Global Note cannot be exchanged for, or transferred to
persons who take delivery thereof in the form of, a beneficial interest in a Restricted Global
Note.

     4.3 Transfer or Exchange of Beneficial Interests for Definitive Notes.

          (a) Beneficial Interests in Restricted Global Notes to Restricted Definitive Notes. If any
holder of a beneficial interest in a Restricted Global Note proposes to exchange such beneficial
interest for a Restricted Definitive Note or to transfer such beneficial interest to a person who
takes delivery thereof in the form of a Restricted Definitive Note, then, upon receipt by the
Registrar of the following documentation:

     (i) if the holder of such beneficial interest in a Restricted Global Note proposes to
exchange such beneficial interest for a Restricted Definitive Note, a certificate from such
holder in the form of Exhibit C hereto, including the certifications in item (2)(a)
thereof;

     (ii) if such beneficial interest is being transferred to a QIB in accordance with Rule
l44A, a certificate to the effect set forth in Exhibit B hereto, including the
certifications in item (1) thereof;

     (iii) if such beneficial interest is being transferred to a Non-U.S. Person in an
offshore transaction in accordance with Rule 903 or Rule 904 under the

8

 

Securities Act, a certificate to the effect set forth in Exhibit B hereto, including
the certifications in item (2) thereof;

     (iv) if such beneficial interest is being transferred pursuant to an exemption from
the registration requirements of the Securities Act in accordance with Rule 144, a
certificate to the effect set forth in Exhibit B hereto, including the certifications in
item (3)(a) thereof;

     (v) if such beneficial interest is being transferred to the Issuer or any of its
Subsidiaries, a certificate to the effect set forth in Exhibit B hereto, including the
certifications in item (3)(b) thereof; or

     (vi) if such beneficial interest is being transferred pursuant to an effective
registration statement under the Securities Act, a certificate to the effect set forth in
Exhibit B hereto, including the certifications in item (3)(c) thereof,

the Trustee shall cause the aggregate principal amount of the applicable Global Note to be reduced
accordingly pursuant to Section 4.8 hereof, and the Issuer shall execute and the Trustee shall
authenticate and deliver to the person designated in the instructions a Definitive Note in the
appropriate principal amount. Any Definitive Note issued in exchange for a beneficial interest in
a Restricted Global Note pursuant to this Section 4.3(a) shall be registered in such name or names
and in such authorized denomination or denominations as the holder of such beneficial interest
shall instruct the Registrar through instructions from the Depositary and the Participant or
Indirect Participant. The Trustee shall make available for delivery such Definitive Notes to the
persons in whose names such Notes are so registered. Any Definitive Note issued in exchange for a
beneficial interest in a Restricted Global Note pursuant to this Section 4.3(a) shall bear the
Private Placement Legend and shall be subject to all restrictions on transfer contained therein.

          (b) Beneficial Interests in Restricted Global Notes to Unrestricted Definitive Notes. A
holder of a beneficial interest in a Restricted Global Note may exchange such beneficial interest
for an Unrestricted Definitive Note or may transfer such beneficial interest to a person who takes
delivery thereof in the form of an Unrestricted Definitive Note only if:

     (i) such exchange or transfer is effected pursuant to the Exchange Offer in accordance
with the Registration Rights Agreement and the holder of such beneficial interest, in the
case of an exchange, or the transferee, in the case of a transfer, certifies in the
applicable Letter of Transmittal that it is not (1) a broker-dealer, (2) a person
participating in the distribution of the Exchange Notes or (3) a person who is an affiliate
(as defined in Rule 144) of the Issuer;

     (ii) such transfer is effected pursuant to the Shelf Registration Statement in
accordance with the Registration Rights Agreement;

     (iii) such transfer is effected by a Participating Broker-Dealer pursuant to the
Exchange Offer Registration Statement in accordance with the Registration Rights Agreement;
or

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     (iv) the Registrar receives the following:

     (A) if the holder of such beneficial interest in a Restricted Global Note proposes
to exchange such beneficial interest for a Definitive Note that does not bear the
Private Placement Legend, a certificate from such holder in the form of Exhibit C
hereto, including the certifications in item (l)(b) thereof; or

     (B) if the holder of such beneficial interest in a Restricted Global Note proposes
to transfer such beneficial interest to a person who shall take delivery thereof in
the form of a Definitive Note that does not bear the Private Placement Legend, a
certificate from such holder in the form of Exhibit B hereto, including the
certifications in item (4) thereof;

and, in each such case set forth in this subparagraph (iv), if the Registrar so requests or if the
Applicable Procedures so require, an Opinion of Counsel in form reasonably acceptable to the
Registrar to the effect that such exchange or transfer is in compliance with the Securities Act and
that the restrictions on transfer contained herein and in the Private Placement Legend are no
longer required in order to maintain compliance with the Securities Act.

     (c) Beneficial Interests in Unrestricted Global Notes to Unrestricted Definitive Notes. If
any holder of a beneficial interest in an Unrestricted Global Note proposes to exchange such
beneficial interest for a Definitive Note or to transfer such beneficial interest to a person who
takes delivery thereof in the form of a Definitive Note, then, upon satisfaction of the conditions
set forth in Section 4.2(b) hereof, the Trustee shall cause the aggregate principal amount of the
applicable Global Note to be reduced accordingly pursuant to Section 4.8 hereof, and the Issuer
shall execute and the Trustee shall authenticate and make available for delivery to the person
designated in the instructions a Definitive Note in the appropriate principal amount. Any
Definitive Note issued in exchange for a beneficial interest pursuant to this Section 4.3(c) shall
be registered in such name or names and in such authorized denomination or denominations as the
holder of such beneficial interest shall instruct the Registrar through instructions from the
Depositary and the Participant or Indirect Participant. The Trustee shall make available for
delivery such Definitive Notes to the persons in whose names such Notes are so registered. Any
Definitive Note issued in exchange for a beneficial interest pursuant to this Section 4.3(c) shall
not bear the Private Placement Legend.

     4.4 Transfer and Exchange of Definitive Notes for Beneficial Interests.

     (a) Restricted Definitive Notes to Beneficial Interests in Restricted Global Notes. If any
Holder of a Restricted Definitive Note proposes to exchange such Note for a beneficial interest in
a Restricted Global Note or to transfer such Restricted Definitive Notes to a person who takes
delivery thereof in the form of a beneficial interest in a Restricted Global Note, then, upon
receipt by the Registrar of the following documentation:

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     (i) if the Holder of such Restricted Definitive Note proposes to exchange such Note
for a beneficial interest in a Restricted Global Note, a certificate from such Holder in
the form of Exhibit C hereto, including the certifications in item (2)(b) thereof;

     (ii) if such Restricted Definitive Note is being transferred to a QIB in accordance
with Rule l44A, a certificate to the effect set forth in Exhibit B hereto, including the
certifications in item (1) thereof;

     (iii) if such Restricted Definitive Note is being transferred to a Non-U.S. Person in
an offshore transaction in accordance with Rule 903 or Rule 904 under the Securities Act, a
certificate to the effect set forth in Exhibit B hereto, including the certifications in
item (2) thereof;

     (iv) if such Restricted Definitive Note is being transferred pursuant to an exemption
from the registration requirements of the Securities Act in accordance with Rule 144, a
certificate to the effect set forth in Exhibit B hereto, including the certifications in
item (3)(a) thereof;

     (v) if such Restricted Definitive Note is being transferred to the Issuer or any of
its Subsidiaries, a certificate to the effect set forth in Exhibit B hereto, including the
certifications in item (3)(b) thereof; or

     (vi) if such Restricted Definitive Note is being transferred pursuant to an effective
registration statement under the Securities Act, a certificate to the effect set forth in
Exhibit B hereto, including the certifications in item (3)(c) thereof;

the Trustee shall cancel the Restricted Definitive Note, increase or cause to be increased the
aggregate principal amount of the appropriate Restricted Global Note.

     (b) Restricted Definitive Notes to Beneficial Interests in Unrestricted Global Notes. A
Holder of a Restricted Definitive Note may exchange such Note for a beneficial interest in an
Unrestricted Global Note or transfer such Restricted Definitive Note to a person who takes delivery
thereof in the form of a beneficial interest in an Unrestricted Global Note only if:

     (i) such exchange or transfer is effected pursuant to the Exchange Offer in accordance
with the Registration Rights Agreement and the Holder, in the case of an exchange, or the
transferee, in the case of a transfer, certifies in the applicable Letter of Transmittal
that it is not (1) a broker-dealer, (2) a person participating in the distribution of the
Exchange Notes or (3) a person who is an affiliate (as defined in Rule 144) of the Issuer;

     (ii) such transfer is effected pursuant to the Shelf Registration Statement in
accordance with the Registration Rights Agreement;

     (iii) such transfer is effected by a Participating Broker-Dealer

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pursuant to the Exchange Offer Registration Statement in accordance with the
Registration Rights Agreement; or

     (iv) the Registrar receives the following:

     (A) if the Holder of such Definitive Notes proposes to exchange such Notes
for a beneficial interest in the Unrestricted Global Note, a certificate
from such Holder in the form of Exhibit C hereto, including the
certifications in item (1)(c) thereof; or

     (B) if the Holder of such Definitive Notes proposes to transfer such Notes
to a person who shall take delivery thereof in the form of a beneficial
interest in the Unrestricted Global Note, a certificate from such Holder in
the form of Exhibit B hereto, including the certifications in item (4)
thereof;

and, in each such case set forth in this subparagraph (iv), if the Registrar so requests or if the
Applicable Procedures so require, an Opinion of Counsel in form reasonably acceptable to the
Registrar to the effect that such exchange or transfer is in compliance with the Securities Act and
that the restrictions on transfer contained herein and in the Private Placement Legend are no
longer required in order to maintain compliance with the Securities Act.

     Upon satisfaction of the conditions of any of the subparagraphs in this Section 4.4(b), the
Trustee shall cancel the Definitive Notes and increase or cause to be increased the aggregate
principal amount of the Unrestricted Global Note.

     (c) Unrestricted Definitive Notes to Beneficial Interests in Unrestricted Global Notes. A
Holder of an Unrestricted Definitive Note may exchange such Note for a beneficial interest in an
Unrestricted Global Note or transfer such Definitive Notes to a person who takes delivery thereof
in the form of a beneficial interest in an Unrestricted Global Note at any time. Upon receipt of a
request for such an exchange or registration of transfer, the Trustee shall cancel the applicable
Unrestricted Definitive Note and increase or cause to be increased the aggregate principal amount
of one of the Unrestricted Global Notes.

     If any such exchange or registration of transfer from a Definitive Note to a beneficial
interest in a Global Note is effected pursuant to subparagraphs (b)(ii), (b)(iv) or (c) above at a
time when an Unrestricted Global Note has not yet been issued, the Issuer shall issue and, upon
receipt of an Issuer Order in accordance with Section 2.4 of the Indenture, the Trustee shall
authenticate one or more Unrestricted Global Notes in an aggregate principal amount equal to the
principal amount of Definitive Notes so transferred.

     4.5 Transfer and Exchange of Definitive Notes for Definitive Notes. Upon request by a
Holder of Definitive Notes and such Holder’s compliance with the provisions of this Section 4.5,
the Registrar shall register the transfer or exchange of Definitive Notes. Prior to such
registration of transfer or exchange, the requesting Holder shall present or

12

 

surrender to the Registrar the Definitive Notes duly endorsed or accompanied by a written
instruction of transfer in form satisfactory to the Registrar duly executed by such Holder or by
his attorney, duly authorized in writing. In addition, the requesting Holder shall provide any
additional certifications, documents and information, as applicable, required pursuant to the
following provisions of this Section 4.5.

     (a) Restricted Definitive Notes to Restricted Definitive Notes. Any Restricted Definitive
Note may be transferred to and registered in the name of persons who take delivery thereof in the
form of a Restricted Definitive Note if the Registrar receives the following:

     (i) if the transfer will be made pursuant to Rule l44A, then the transferor must
deliver a certificate in the form of Exhibit B hereto, including the certifications in item
(1) thereof; and

     (ii) if the transfer will be made pursuant to Rule 903 or Rule 904 under the
Securities Act, then the transferor must deliver a certificate in the form of Exhibit B
hereto, including the certifications in item (2) thereof;

     (iii) if the transfer will be made pursuant to any other exemption from the
registration requirements of the Securities Act, then the transferor must deliver a
certificate in the form of Exhibit B hereto, including the certifications, certificates and
Opinion of Counsel required by item (3) thereof, if applicable.

     (b) Restricted Definitive Notes to Unrestricted Definitive Notes. Any Restricted Definitive
Note may be exchanged by the Holder thereof for an Unrestricted Definitive Note or transferred to a
person or persons who take delivery thereof in the form of an Unrestricted Definitive Note if:

     (i) such exchange or transfer is effected pursuant to the Exchange Offer in accordance
with the Registration Rights Agreement and the Holder, in the case of an exchange, or the
transferee, in the case of a transfer, certifies in the applicable Letter of Transmittal
that it is not (1) a broker-dealer, (2) a person participating in the distribution of the
Exchange Notes or (3) a person who is an affiliate (as defined in Rule 144) of the Issuer;

     (ii) any such transfer is effected pursuant to the Shelf Registration Statement in
accordance with the Registration Rights Agreement;

     (iii) any such transfer is effected by a Participating Broker-Dealer pursuant to the
Exchange Offer Registration Statement in accordance with the Registration Rights Agreement;
or

     (iv) the Registrar receives the following:

     (A) if the Holder of such Restricted Definitive Notes proposes to exchange such
Notes for an Unrestricted Definitive Note, a certificate from

13

 

such Holder in the form of Exhibit C hereto, including the certifications in item
(1)(d) thereof; or

     (B) if the Holder of such Restricted Definitive Notes proposes to transfer such
Notes to a person who shall take delivery thereof in the form of an Unrestricted
Definitive Note, a certificate from such Holder in the form of Exhibit B hereto,
including the certifications in item (4) thereof;

and, in each such case set forth in this subparagraph (iv), if the Registrar so requests, an
Opinion of Counsel in form reasonably acceptable to the Issuer to the effect that such exchange or
transfer is in compliance with the Securities Act and that the restrictions on transfer contained
herein and in the Private Placement Legend are no longer required in order to maintain compliance
with the Securities Act.

     (c) Unrestricted Definitive Notes to Unrestricted Definitive Notes. A Holder of Unrestricted
Definitive Notes may transfer such Notes to a person who takes delivery thereof in the form of an
Unrestricted Definitive Note. Upon receipt of a request to register such a transfer, the Registrar
shall register the Unrestricted Definitive Notes pursuant to the instructions from the Holder
thereof.

     4.6 Exchange Offer. Upon the occurrence of the Exchange Offer in accordance with the
Registration Rights Agreement, the Issuer shall issue and, upon receipt of an Issuer Order in
accordance with Section 2.4 of the Indenture, the Trustee shall authenticate (i) one or more
Unrestricted Global Notes in an aggregate principal amount equal to the principal amount of the
beneficial interests in the Restricted Global Notes tendered for acceptance by persons that certify
in the applicable Letters of Transmittal or via the Depositary’s book-entry system that (x) they
are not broker-dealers, (y) they are not participating in a distribution of the Exchange Notes and
(z) they are not affiliates (as defined in Rule 144) of the Issuer, and accepted for exchange in
the Exchange Offer and (ii) Definitive Notes in an aggregate principal amount equal to the
principal amount of the Restricted Definitive Notes accepted for exchange in the Exchange Offer.
In addition, if pursuant to the Registration Rights Agreement, any Holder is entitled to receive
Private Exchange Notes simultaneously with the consummation of the Exchange Offer and so requests,
the Issuer shall issue and, upon receipt of an Issuer Order in accordance with Section 2.4 of the
Indenture, the Trustee shall authenticate (i) one or more Restricted Global Notes that are
identical in all material respects to the Exchange Notes, except for the Private Placement Legend,
in an aggregate principal amount equal to the principal amount of the beneficial interests in the
Restricted Global Notes accepted for exchange in the Private Exchange and (ii) Restricted
Definitive Notes that are identical in all material respects to the Exchange Notes, except for the
Private Placement Legend, in an aggregate principal amount equal to the principal amount of the
Restricted Definitive Notes accepted for exchange in the Private Exchange. Concurrently with the
issuance of such Notes, the Trustee shall cause the aggregate principal amount of the applicable
Restricted Global Notes to be reduced accordingly, and the Issuer shall execute and the Trustee
shall authenticate and make available for delivery to the persons designated by the Holders of
Definitive Notes so accepted Definitive Notes in the appropriate principal amount.

14

 

     4.7 Legends. The following legends shall appear on the face of all Global Notes and
Definitive Notes issued under this Sixth Supplemental Indenture unless specifically stated
otherwise in the applicable provisions hereof:

     (a) Private Placement Legend. Except as permitted by subparagraph (b) below, each Global Note
and each Definitive Note (and all Notes issued in exchange therefor or substitution thereof) shall
bear the legend in substantially the following form:

“THE HOLDER OF THIS SECURITY BY ITS ACCEPTANCE HEREOF IS DEEMED TO HAVE AGREED TO BE BOUND
BY THE PROVISIONS OF A REGISTRATION RIGHTS AGREEMENT AMONG WYETH AND THE INITIAL
PURCHASERS, DATED NOVEMBER 14, 2005 (THE “REGISTRATION RIGHTS AGREEMENT”). WE WILL
PROVIDE A COPY OF THE REGISTRATION RIGHTS AGREEMENT TO A HOLDER WITHOUT CHARGE UPON WRITTEN
REQUEST TO US AT OUR PRINCIPAL PLACE OF BUSINESS.

THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE
“SECURITIES ACT”), OR THE SECURITIES LAWS OF ANY STATE OR OTHER JURISDICTION.
NEITHER THIS SECURITY NOR ANY INTEREST OR PARTICIPATION HEREIN MAY BE REOFFERED, SOLD,
ASSIGNED, TRANSFERRED, PLEDGED, ENCUMBERED OR OTHERWISE DISPOSED OF IN THE ABSENCE OF SUCH
REGISTRATION OR UNLESS SUCH TRANSACTION IS EXEMPT FROM, OR NOT SUBJECT TO, SUCH
REGISTRATION.

THE HOLDER OF THIS SECURITY, BY ITS ACCEPTANCE HEREOF, AGREES ON ITS OWN BEHALF AND ON
BEHALF OF ANY INVESTOR ACCOUNT FOR WHICH IT HAS PURCHASED SECURITIES TO OFFER, SELL OR
OTHERWISE TRANSFER SUCH SECURITY, PRIOR TO THE DATE (THE “RESALE RESTRICTION
TERMINATION DATE”) WHICH IS TWO YEARS AFTER THE LATER OF THE ORIGINAL ISSUE DATE HEREOF
AND THE LAST DATE ON WHICH WYETH (THE “COMPANY”) OR ANY AFFILIATE OF THE COMPANY
WAS THE OWNER OF THIS SECURITY (OR ANY PREDECESSOR OF SUCH SECURITY), ONLY (A) TO THE
COMPANY, (B) PURSUANT TO A REGISTRATION STATEMENT THAT HAS BEEN DECLARED EFFECTIVE UNDER
THE SECURITIES ACT, (C) FOR SO LONG AS THE SECURITIES ARE ELIGIBLE FOR RESALE PURSUANT TO
RULE l44A UNDER THE SECURITIES ACT (“RULE l44A”), TO A PERSON IT REASONABLY
BELIEVES IS A “QUALIFIED INSTITUTIONAL BUYER” AS DEFINED IN RULE l44A THAT PURCHASES FOR
ITS OWN ACCOUNT OR FOR THE ACCOUNT OF A QUALIFIED INSTITUTIONAL BUYER TO WHOM NOTICE IS
GIVEN THAT THE TRANSFER IS BEING MADE IN RELIANCE ON RULE l44A, (D) IN AN OFFSHORE
TRANSACTION IN COMPLIANCE WITH RULE 903 OR RULE 904 OF REGULATION S UNDER THE SECURITIES
ACT OR (E) PURSUANT TO ANY OTHER AVAILABLE EXEMPTION FROM THE REGISTRATION

15

 

REQUIREMENTS OF THE SECURITIES ACT, SUBJECT TO THE COMPANY’S AND THE TRUSTEE’S RIGHT PRIOR
TO ANY SUCH OFFER, SALE OR TRANSFER PURSUANT TO CLAUSES (D) OR (E) TO REQUIRE THE DELIVERY
OF AN OPINION OF COUNSEL, CERTIFICATION AND/OR OTHER INFORMATION SATISFACTORY TO EACH OF
THEM. THIS LEGEND WILL BE REMOVED UPON THE REQUEST OF THE HOLDER AFTER THE RESALE
RESTRICTION TERMINATION DATE.”

If Definitive Notes are issued, each Definitive Note will bear the following additional legend:

“IN CONNECTION WITH ANY TRANSFER, THE HOLDER WILL DELIVER TO THE REGISTRAR AND TRANSFER
AGENT SUCH CERTIFICATES AND OTHER INFORMATION AS SUCH TRANSFER AGENT MAY REASONABLY REQUIRE
TO CONFIRM THAT THE TRANSFER COMPLIES WITH THE FOREGOING RESTRICTIONS.”

Notwithstanding the foregoing, any Global Note or Definitive Note issued pursuant to Sections
4.2(d), 4.3(b), 4.4(b), 4.4(c), 4.5(b), 4.5(c) or 4.6 (and all Notes issued in exchange therefor or
substitution thereof) shall not bear the Private Placement Legend.

     (b) Global Note Legends. Each Global Note shall bear legends in substantially the following
form:

“THIS [GLOBAL NOTE] [OFFSHORE GLOBAL NOTE] IS HELD BY THE DEPOSITARY (AS DEFINED IN THE
INDENTURE GOVERNING THIS NOTE) OR ITS NOMINEE IN CUSTODY FOR THE BENEFIT OF THE BENEFICIAL
OWNERS HEREOF, AND IS NOT TRANSFERABLE TO ANY PERSON UNDER ANY CIRCUMSTANCES EXCEPT THAT
(I) THE TRUSTEE MAY MAKE SUCH NOTATIONS HEREON AS MAY BE REQUIRED PURSUANT TO SECTION 2.9
OF THE INDENTURE, (II) THIS [GLOBAL NOTE] [OFFSHORE GLOBAL NOTE] MAY BE EXCHANGED IN WHOLE
BUT NOT IN PART PURSUANT TO SECTION 4.1 OF THE SIXTH SUPPLEMENTAL INDENTURE, (III) THIS
[GLOBAL NOTE] [OFFSHORE GLOBAL NOTE] MAY BE DELIVERED TO THE TRUSTEE FOR CANCELLATION
PURSUANT TO SECTION 2.10 OF THE INDENTURE AND (IV) THIS [GLOBAL NOTE] [OFFSHORE GLOBAL
NOTE] MAY BE TRANSFERRED TO A SUCCESSOR DEPOSITARY WITH THE PRIOR WRITTEN CONSENT OF THE
COMPANY.

UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR NOTES IN DEFINITIVE FORM, THIS
NOTE MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE
DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE OF THE
DEPOSITARY OR BY THE DEPOSITARY OR ANY SUCH NOMINEE TO A SUCCESSOR DEPOSITARY OR A NOMINEE
OF SUCH SUCCESSOR DEPOSITARY. UNLESS THIS

16

 

CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY
(55 WATER STREET, NEW YORK, NEW YORK) (“DTC”) TO THE COMPANY OR ITS AGENT FOR
REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN
THE NAME OF CEDE & CO. OR SUCH OTHER NAME AS MAY BE REQUESTED BY AN AUTHORIZED
REPRESENTATIVE OF DTC (AND ANY PAYMENT IS MADE TO CEDE & CO. OR SUCH OTHER ENTITY AS MAY
BE REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE
HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED
OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN.”

     (c) Temporary Offshore Global Note Legend. Each Offshore Global Note initially shall bear a
legend in substantially the following form:

THIS NOTE IS AN OFFSHORE GLOBAL NOTE. PRIOR TO THE EXPIRATION OF THE RELEVANT 40-DAY
DISTRIBUTION COMPLIANCE PERIOD APPLICABLE HERETO, AS DEFINED AND PROVIDED IN REGULATION S
(THE “RESTRICTED PERIOD”), BENEFICIAL INTERESTS HEREIN MAY NOT BE HELD BY ANY PERSON OTHER
THAN (1) A NON-U.S. PERSON OR (2) A U.S. PERSON THAT PURCHASED SUCH INTEREST IN A
TRANSACTION EXEMPT FROM REGISTRATION UNDER THE U.S. SECURITIES ACT OF 1933, AS AMENDED (THE
“SECURITIES ACT”). UPON EXPIRATION OF THE RESTRICTED PERIOD THIS LEGEND WILL BE REMOVED.
TERMS IN THIS LEGEND ARE USED AS USED IN REGULATION S UNDER THE SECURITIES ACT (“REGULATION
S”).

     4.8 Cancellation and/or Adjustment of Global Notes. At such time as all beneficial
interests in a particular Global Note have been exchanged for Definitive Notes or a particular
Global Note has been redeemed, repurchased or canceled in whole and not in part, each such Global
Note shall be returned to or retained and canceled by the Trustee in accordance with Section 2.10
of the Indenture. At any time prior to such cancellation, if any beneficial interest in a Global
Note is exchanged for or transferred to a person who will take delivery thereof in the form of a
beneficial interest in another Global Note or for Definitive Notes, the principal amount of Notes
represented by such Global Note shall be reduced accordingly and an endorsement shall be made on
such Global Note by the Trustee or by the Depositary at the direction of the Trustee to reflect
such reduction; and if the beneficial interest is being exchanged for or transferred to a person
who will take delivery thereof in the form of a beneficial interest in another Global Note, such
other Global Note shall be increased accordingly and an endorsement shall be made on such Global
Note by the Trustee or by the Depositary at the direction of the Trustee to reflect such increase.

     SECTION 5. MISCELLANEOUS.

     5.1 Ratification of Indenture. The Indenture, as supplemented by this Sixth
Supplemental Indenture, is in all respects ratified and confirmed, and this Sixth

17

 

Supplemental Indenture shall be deemed a part of the Indenture in the manner and to the extent
herein and therein provided.

     5.2 GOVERNING LAW. THIS SIXTH SUPPLEMENTAL INDENTURE, EACH NOTE AND THE RIGHTS AND
OBLIGATIONS OF THE PARTIES UNDER THIS SIXTH SUPPLEMENTAL INDENTURE AND EACH NOTE SHALL BE GOVERNED
BY, AND CONSTRUED AND INTERPRETED IN ACCORDANCE WITH, THE LAW OF THE STATE OF NEW YORK.

     5.3 Counterparts. This Sixth Supplemental Indenture may be executed in several
counterparts, each of which shall be an original, and all collectively but one instrument.

     5.4 The Trustee. The Trustee shall not be responsible in any manner whatsoever for or
in respect of the validity or sufficiency of this Sixth Supplemental Indenture or for or in respect
of the recitals contained herein, all of which are made solely by the Issuer.

18

 

EXECUTION COPY

     IN WITNESS WHEREOF, the parties hereto have caused this Sixth Supplemental Indenture to be
executed as of the date first above written.

	 	 	 	 	 
	 	WYETH, as Issuer 

 	 
	 	By:  	/s/ Jack M. O'Connor	 
	 	 	Name:  Jack M. O'Connor
	 	 	Title:  Vice President and Treasurer
	 

	 	 	 	 	 
	 	JPMORGAN CHASE BANK, N.A., as Trustee

 	 
	 	By:  	/s/ Francine Springer	 
	 	 	Name:  Francine Springer
	 	 	Title:  Vice President
	 

 

 

EXECUTION COPY

EXHIBIT A

[FACE OF NOTE]

[Insert Global Note Legends, if applicable pursuant to the provisions of the Sixth

Supplemental Indenture]

[Insert the Private Placement Legend, if applicable pursuant to the provisions of the Sixth

Supplemental Indenture]

[Insert the Temporary Offshore Global Note Legend, if applicable pursuant to the provisions of the

Sixth Supplemental Indenture]

			
	No.                    
	 	$                    
	 
	 	CUSIP:                    

WYETH

•% [Series A] [Series B] Notes due ___

	 	 	 
	ORIGINAL ISSUE

	 	INTEREST PAYMENT
	DATE:

	 	DATES:
	 
	 	 
	INTEREST RATE:

	 	APPLICABILITY OF
	 

	 	OPTIONAL
	 

	 	REDEMPTION
	 

	 	PROVISIONS:
	 
	 	 
	MATURITY DATE:
	 	 

     Wyeth (as successor to American Home Products Corporation), a Delaware corporation
(together with its successors and assigns, the “Issuer”), for value received, hereby
promises to pay to ___, or registered assignees, the principal sum of___on the Maturity
Date specified above and to pay interest thereon at the Interest Rate per annum specified above,
semiannually in arrears on each Interest Payment Date specified above during each year commencing
on the Interest Payment Date next succeeding the Original Issue Date specified above, and at
maturity (or on any redemption or repayment date).

     Interest on this Note will accrue from the most recent Interest Payment Date to which interest
has been paid or duly provided for, or, if no interest has been paid or duly provided for, from the
Original Issue Date, until the principal hereof has been paid or duly made available for payment
(except as provided below). The interest so payable, and punctually paid or duly provided for, on
any Interest Payment Date will, subject to certain exceptions described herein, be paid to the
person in whose name this Note (or one or more

A-1

 

predecessor Notes) is registered at the close of business on the date 15 calendar days prior
to such Interest Payment Date (whether or not a Business Day) (each such date a “Record
Date”); provided, however, that interest payable at maturity (or on any redemption or repayment
date) will be payable to the person to whom the principal hereof shall be payable. As used herein,
“Business Day” means any day, other than a Saturday or Sunday, that is neither a legal
holiday nor a day on which banking institutions are authorized or required by law or regulation to
close in The City of New York.

     Payment of the principal of this Note, any premium and the interest due at maturity (or on any
redemption or repayment date) will be made in immediately available funds upon surrender of this
Note at the office or agency of the Paying Agent, as defined on the reverse hereof, maintained for
that purpose in the Borough of Manhattan, The City of New York, or at such other paying agency as
the Issuer may determine. Payment of the principal of and premium, if any, and interest on this
Note will be made by U.S. dollar check mailed to the address of the person entitled thereto as such
address shall appear in the Note register. A holder of U.S. $10,000,000 or more in aggregate
principal amount of Notes having the same Interest Payment Date will be entitled to receive
payments of interest, other than interest due at maturity or on any date of redemption or
repayment, by wire transfer of immediately available funds if appropriate wire transfer
instructions have been received by the Paying Agent in writing not less than 15 calendar days prior
to the applicable Interest Payment Date.

     Reference is hereby made to the further provisions of this Note set forth on the reverse
hereof; which further provisions shall for all purposes have the same effect as if set forth at
this place.

     Unless the certificate of authentication hereon has been executed by the Trustee referred to
on the reverse hereof by manual signature, this Note shall not be entitled to any benefit under the
Indenture, as defined on the reverse hereof, or be valid or obligatory for any purpose.

A-2

 

     IN WITNESS WHEREOF, the Issuer has caused this Note to be duly executed under its corporate
seal.

     DATED:

	 	 	 	 	 
	 	WYETH 

 	 
	 	By:  	 	 
	 	 	Name:  	 	 
	 	 	Title:  	 	 
	 

TRUSTEE’S CERTIFICATE

OF AUTHENTICATION

This is one of the Notes referred

to in the within-mentioned Indenture.

	 	 	 	 	 
	 	JPMORGAN CHASE BANK, N.A., as Trustee 

 	 
	 	By:  	 	 
	 	 	Name:  	 	 
	 	 	Title:  	Authorized Officer 	 

A-3

 

	 	 	 	 	 

[BACK OF NOTE]

     This Note is one of a duly authorized issue of [ ]% Series [A] [B] Notes due ___(the
“Notes”) of the Issuer. The Notes are issuable under an indenture, dated as of April 10,
1992 (as amended by the Supplemental Indenture dated as of October 13, 1992, and as further amended
by the Sixth Supplemental Indenture dated as of November 14, 2005, the “Indenture”), each
between the Issuer and JPMorgan Chase Bank, N.A. (successor to Manufacturers Hanover Trust
Company), as Trustee (the “Trustee,” which term includes any successor trustee under the
Indenture), to which Indenture and all indentures supplemental thereto reference is hereby made for
a statement of the respective rights, limitations of rights, duties and immunities of the Issuer,
the Trustee and holders of the Notes and the terms upon which the Notes are, and are to be,
authenticated and delivered. The Issuer has appointed JPMorgan Chase Bank, N.A., at its principal
corporate trust office in The City of New York as the paying agent (the “Paying Agent,”
which term includes any additional or successor Paying Agent appointed by the Issuer) with respect
to the Notes. The terms of individual Notes may vary with respect to interest rates, interest rate
formulas, issue dates, maturity dates or otherwise, all as provided in the Indenture. To the
extent not inconsistent herewith, the terms of the Indenture are hereby incorporated by reference
herein.

     If so indicated on the face of this Note, this Note may be redeemed in whole or in part at the
option of the Issuer upon payment of the redemption price specified below. If the Issuer exercises
the option to redeem this Note, the redemption price will equal the greater of (i) 100% of the
principal amount of this Note or (ii) the sum, as determined by the Quotation Agent (defined
below), of the present value of the principal amount of this Note and the remaining scheduled
payments of interest on this Note from the redemption date to the Maturity Date, exclusive of
interest accrued to the redemption date (the “Remaining Life”), discounted from the scheduled
payment dates to the redemption date on a semiannual basis (assuming a 360-day year of 30-day
months) at the Treasury Rate (defined below) plus • basis points, plus accrued and unpaid interest
on the principal amount being redeemed to the date of redemption. Notice of redemption shall be
mailed to the registered holders of the Notes designated for redemption at their addresses as the
same shall appear on the Note register not less than 30 nor more than 60 days prior to the date
fixed for redemption, subject to all the conditions and provisions of the Indenture. In the event
of redemption of this Note in part only, a new Note or Notes for the amount of the unredeemed
portion hereof shall be issued in the name of the holder hereof upon the cancellation hereof.

     For purposes of the immediately preceding paragraph, the following defined terms shall have
the meanings specified:

     “Comparable Treasury Issue” means the United States Treasury security selected by the
Quotation Agent as having a maturity comparable to the Remaining Life that would be utilized, at
the time of selection and in accordance with customary financial practice, in pricing new issues of
corporate debt securities of comparable maturity with the Remaining Life.

A-4

 

     “Comparable Treasury Price” means, with respect to any redemption date, the average of two
Reference Treasury Dealer Quotations for such redemption date.

     “Quotation Agent” means the Reference Treasury Dealer appointed by the Issuer.

     “Reference Treasury Dealer” means each of J.P. Morgan Securities Inc. and Citigroup Global
Markets Inc., and their successors; provided, however, that if any of the foregoing ceases to be a
primary U.S. Government securities dealer in New York City (a “Primary Treasury Dealer”), the
Issuer will substitute therefor another Primary Treasury Dealer.

     “Reference Treasury Dealer Quotations” means, with respect to each Reference Treasury Dealer
and any redemption date, the average, as determined by the Trustee, of the bid and asked price for
the Comparable Treasury Issue (expressed in each case as a percentage of its principal amount)
quoted in writing to the Trustee by such Reference Treasury Dealer at 5:00 p.m., New York City
time, on the third Business Day preceding such redemption date.

     “Treasury Rate” means, with respect to any redemption date, the rate per annum equal to the
semiannual yield to maturity of the Comparable Treasury Issue, calculated on the third business day
preceding such redemption date using a price for the Comparable Treasury Issue (expressed as a
percentage of its principal amount) equal to the Comparable Treasury Price for such redemption
date.

     Interest payments on this Note will include interest accrued to but excluding the Interest
Payment Dates or the Maturity Date (or any earlier redemption or repayment date), as the case may
be. Interest payments for this Note will be computed and paid on the basis of a 360-day year of
twelve 30-day months.

     In the case where the Interest Payment Date or the Maturity Date (or any redemption or
repayment date) does not fall on a Business Day, payment of interest, premium, if any, or principal
otherwise payable on such date need not be made on such date, but may be made on the next
succeeding Business Day with the same force and effect as if made on the Interest Payment Date or
on the Maturity Date (or any redemption or repayment date), and no interest on such payment shall
accrue for the period from and after the Interest Payment Date or the Maturity Date (or any
redemption or repayment date) to such next succeeding Business Day.

     This Note and all the obligations of the Issuer hereunder are direct, unsecured obligations of
the Issuer and rank without preference or priority among themselves and pari passu with all other
existing and future unsecured and unsubordinated indebtedness of the Issuer, subject to certain
statutory exceptions in the event of liquidation upon insolvency.

     This Note, and any Note or Notes issued upon registration of transfer or exchange hereof, is
issuable only in fully registered form, without coupons, and is issuable only in denominations of
U.S. $2,000 and any integral multiple of U.S. $1,000 in excess thereof.

A-5

 

     The Trustee has been appointed registrar for the Notes, and the Trustee will maintain at its
principal corporate trust office in The City of New York a register for the registration and
transfer of Notes. This Note may be transferred at the aforesaid office of the Trustee by
surrendering this Note for cancellation, accompanied by a written instrument of transfer in form
satisfactory to the Trustee and duly executed by the registered holder hereof in person or by the
holder’s attorney duly authorized in writing, and thereupon the Trustee shall issue in the name of
the transferee or transferees, in exchange herefor, a new Note or Notes having identical terms and
provisions and having a like aggregate principal amount in authorized denominations, subject to the
terms and conditions set forth herein; provided, however, that the Trustee will not
be required (i) to register the transfer of or exchange any Note that has been called for
redemption in whole or in part, except the unredeemed portion of Notes being redeemed in part, (ii)
to register the transfer of or exchange any Note if the holder thereof has exercised his right, if
any, to require the Issuer to repurchase such Note in whole or in part, except the portion of such
Note not required to be repurchased, or (iii) to register the transfer of or exchange Notes to the
extent and during the period so provided in the Indenture with respect to the redemption of Notes.
Notes are exchangeable at said office for other Notes of other authorized denominations of equal
aggregate principal amount having identical terms and provisions. All such exchanges and transfers
of Notes will be free of charge, but the Issuer or the Trustee may require payment of a sum
sufficient to cover any tax or other governmental charge in connection therewith. All Notes
surrendered for exchange shall be accompanied by a written instrument of transfer in form
satisfactory to the Trustee and executed by the registered holder in person or by the holder’s
attorney duly authorized in writing. The date of registration of any Note delivered upon any
exchange or transfer of Notes shall be such that no gain or loss of interest results from such
exchange or transfer.

     In case any Note shall at any time become mutilated, defaced or be destroyed, lost or stolen
and such Note or evidence of the loss, theft or destruction thereof (together with the indemnity
hereinafter referred to and such other documents or proof as may be required in the premises) shall
be delivered to the Trustee, a new Note of like tenor will be issued by the Issuer in exchange for
the Note so mutilated or defaced, or in lieu of the Note so destroyed or lost or stolen, but, in
the case of any destroyed or lost or stolen Note, only upon receipt of evidence satisfactory to the
Trustee and the Issuer that such Note was destroyed or lost or stolen and, if required, upon
receipt also of indemnity satisfactory to each of them. All expenses and reasonable charges
associated with procuring such indemnity and with the preparation, authentication and delivery of a
new Note shall be borne by the owner of the Note mutilated, defaced, destroyed, lost or stolen.

     The Indenture provides that, (a) if an Event of Default (as defined in the Indenture) due to
the default in payment of principal of, or interest on, any series of debt securities issued under
the Indenture, including the series of Notes of which this Note forms a part, or due to the default
in the performance or breach of any other covenant or warranty of the Issuer applicable to the debt
securities of such series but not applicable to all outstanding debt securities issued under the
Indenture shall have occurred and be continuing, either the Trustee or the holders of not less than
25% in aggregate principal amount of all affected debt securities issued under the Indenture then
outstanding (treated as one class) may then declare the principal of all debt securities of all
such series and interest accrued thereon to

A-6

 

be due and payable immediately and (b) if an Event of Default due to a default in the
performance of any other of the covenants or agreements in the Indenture applicable to all
outstanding debt securities issued thereunder, including this Note, or due to certain events of
bankruptcy, insolvency and reorganization of the Issuer, shall have occurred and be continuing,
either the Trustee or the holders of not less than 25% in aggregate principal amount of all debt
securities issued under the Indenture then outstanding (treated as one class) may declare the
principal of all such debt securities and interest accrued thereon to be due and payable
immediately, but upon certain conditions such declarations may be annulled and past defaults may be
waived (except a continuing default in payment of principal of, or interest on, such debt
securities) by the holders of a majority in principal amount of the debt securities of all affected
series then outstanding.

     The Indenture permits the Issuer and the Trustee, with the consent of the holders of not less
than a majority in aggregate principal amount of the debt securities of all series issued under the
Indenture then outstanding and affected (voting as one class), to execute supplemental indentures
adding any provisions to or changing in any manner the rights of the holders of each series so
affected; provided that the Issuer and the Trustee may not, without the consent of the holder of
each outstanding debt security affected thereby, (a) extend the final maturity of any such debt
security, or reduce the principal amount thereof; or reduce the rate or extend the time of payment
of interest thereon, or reduce any amount payable on redemption or repayment thereof; or change the
currency of payment thereof, or impair or affect the right of any holder to institute suit for the
payment thereof; or (b) reduce the aforesaid percentage in principal amount of debt securities the
consent of the holders of which is required for any such supplemental indenture; or (c) modify any
of the foregoing provisions except to increase any such percentage or to provide that other
provisions cannot be modified or waived without the consent of each affected holder.

     So long as this Note shall be outstanding, the Issuer will cause to be maintained an office or
agency for the payment of the principal of and premium, if any, and interest on this Note as herein
provided in the Borough of Manhattan, The City of New York, and an office or agency in said Borough
of Manhattan for the registration, transfer and exchange as aforesaid of the Notes. The Issuer may
designate other agencies for the payment of said principal, premium and interest at such place or
places (subject to applicable laws and regulations) as the Issuer may decide. So long as there
shall be such an agency, the Issuer shall keep the Trustee advised of the names and locations of
such agencies, if any are so designated.

     With respect to moneys paid by the Issuer and held by the Trustee or any Paying Agent for
payment of the principal of or interest or premium, if any, on any Notes that remain unclaimed at
the end of two years after such principal, interest or premium shall have become due and payable
(whether at maturity or upon call for redemption or otherwise), (i) the Trustee or such Paying
Agent shall notify the holders of such Notes that such moneys shall be repaid to the Issuer and any
person claiming such moneys shall thereafter look only to the Issuer for payment thereof and (ii)
such moneys shall be so repaid to the Issuer. Upon such repayment all liability of the Trustee or
such Paying Agent with respect to such moneys shall thereupon cease, without, however, limiting in
any way

A-7

 

any obligation that the Issuer may have to pay the principal of or interest or premium, if
any, on this Note as the same shall become due.

     No provision of this Note or of the Indenture shall alter or impair the obligation of the
Issuer, which is absolute and unconditional, to pay the principal of, premium, if any, and interest
on this Note at the time, place and rate, and in the coin and currency, herein prescribed unless
otherwise agreed between the Issuer and the registered holder of this Note.

     Prior to due presentment of this Note for registration of transfer, the Issuer, the Trustee
and any agent of the Issuer or the Trustee may treat the holder in whose name this Note is
registered as the owner hereof for all purposes, whether or not this Note be overdue, and none of
the Issuer, the Trustee or any such agent shall be affected by notice to the contrary.

     No recourse under or upon any obligation, covenant or agreement contained in the Indenture, or
in this Note, or because of the indebtedness evidenced hereby, shall be had against any
incorporator, as such, or against any past, present or future stockholder, officer or director, as
such, of the Issuer or of any successor, either directly or through the Issuer or any successor,
under any rule of law, statute or constitutional provision or by the enforcement of any assessment
or by any legal or equitable proceeding or otherwise, all such liability being, by the acceptance
hereof and as part of the consideration for the issuance hereof, expressly waived and released.

     This Note shall for all purposes be governed by, and construed in accordance with, the laws of
the State of New York.

     All terms used in this Note which are defined in the Indenture and not otherwise defined
herein shall have the meanings assigned to them in the Indenture.

A-8

 

Assignment Form

To assign this Note, fill in the form below: (I) or (we) assign and transfer this Note to

 

(Insert assignee’s soc. sec. or tax I.D. no.)

 

 

 

 

 

(Print or type assignee’s name, address and zip code)

and irrevocably appoint

to transfer this Note on the books of the Issuer. The agent may substitute another to act for
him.

 

	 	 	 
	Date:
	 	 
	 
	 	 
	 

	 	Your Signature:
	 
	 	 
	 

	 	(Sign exactly as your name appears on the face of
this Note)
	 
	 	 
	 

	 	Tax Identification No:
	 
	 	 
	 

	 	SIGNATURE GUARANTEE:
	 
	 	 
	 	 	 
	 
	 	 
	 

	 	Signatures must be guaranteed by an “eligible guarantor
institution” meeting the requirements of the Registrar,
which requirements include membership or participation in
the Security Transfer Agent Medallion Program (“STAMP”) or
such other “signature guarantee program” as may be
determined by the Registrar in addition to, or in
substitution for, STAMP, all in accordance with the
Securities Exchange Act of 1934, as amended.

A-9

 

SCHEDULE OF EXCHANGES OF INTERESTS IN THE GLOBAL NOTE1

     The following exchanges of a part of this Global Note for an interest in another Global
Note or for a Definitive Note, or exchanges of a part of another Global Note or Definitive Note for
an interest in this Global Note, have been made:

	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 
	 	 	 	 	 	 	 	 	 	 	Principal Amount of	 	 	 	 
	 	 	 	 	 	 	 	 	 	 	this Global Note	 	 	 	 
	 	 	Amount of decrease	 	 	Amount of increase	 	 	following such	 	 	Signature of	 
	Date of	 	in Principal Amount	 	 	in Principal Amount	 	 	decrease (or	 	 	authorized officer	 
	Exchange	 	of this Global Note	 	 	of this Global Note	 	 	increase)	 	 	of Trustee	 
	 
	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 

 

			
	1	 	This should be included only if the Note is
issued in global form.

A-10

 

EXECUTION COPY

EXHIBIT B

[FORM OF CERTIFICATE OF TRANSFER]

Wyeth

Five Giralda Farms

Madison, New Jersey 07940

Attention: Secretary of the Company

JPMorgan Chase Bank, N.A.

4 New York Plaza

15th Floor

New York, NY 10004

Attention: Worldwide Securities Services

     Re: •% Series A Notes due                     

     Reference is hereby made to the Indenture, dated as of April 10, 1992, as amended by the
Supplemental Indenture, dated as of October 13, 1992 and as further amended by the Sixth
Supplemental Indenture, date as of November 14, 2005 (as so amended and supplemented, the
"Indenture”), between Wyeth (as successor to American Home Products Corporation), a Delaware
corporation, as issuer (the “Company”), and JPMorgan Chase Bank, N.A. (as successor to
Manufacturers Hanover Trust Company), as trustee. Capitalized terms used but not defined herein
shall have the meanings given to them in the Indenture.

                         , (the “Transferor”) owns and proposes to transfer the Note[s] or interest in such
Note[s] specified in Annex A hereto, in the principal amount of $                     in such Note[s] or
interests (the “Transfer”), to                      (the “Transferee”), as further specified in Annex A
hereto. In connection with the Transfer, the Transferor hereby certifies that:

[CHECK ALL THAT APPLY]

	1.	 	o Check if Transferee will take delivery of a beneficial interest in a Restricted
Global Note or a Restricted Definitive Note Pursuant to Rule 144A. The Transfer is being
effected pursuant to and in accordance with Rule l44A under the United States Securities Act
of 1933, as amended (the “Securities Act”), and, accordingly, the Transferor hereby further
certifies that the beneficial interest or Restricted Definitive Note is being transferred to a
person that the Transferor reasonably believed and believes is purchasing the beneficial
interest or Restricted Definitive Note for its own account, or for one or more accounts with
respect to which such person exercises sole investment discretion, and such person and each
such account is a “qualified institutional buyer” within the meaning of Rule 144A in a
transaction meeting the requirements of Rule 144A and such Transfer is in

B-1

 

	 	 	compliance with any applicable blue sky securities laws of any state of the United States.
Upon consummation of the proposed Transfer in accordance with the terms of the Indenture,
the transferred beneficial interest or Restricted Definitive Note will be subject to the
restrictions on transfer enumerated in the Private Placement Legend printed on the
Restricted Global Note and/or the Restricted Definitive Note and in the Indenture and the
Securities Act.

	2.	 	o Check if Transferee will take delivery of a beneficial interest in a Restricted
Global Note or a Restricted Definitive Note Pursuant to Regulation S. The Transfer is being
effected pursuant to and in accordance with Rule 903 or Rule 904 under the Securities Act and,
accordingly, the Transferor hereby further certifies that (i) the Transfer is not being made
to a person in the United States and (x) at the time the buy order was originated, the
Transferee was outside the United States or such Transferor and any person acting on its
behalf reasonably believed and believes that the Transferee was outside the United States or
(y) the transaction was executed in, on or through the facilities of a designated offshore
securities market and neither such Transferor nor any person acting on its behalf knows that
the transaction was prearranged with a buyer in the United States, (ii) no directed selling
efforts have been made in contravention of the requirements of Rule 903(b) or Rule 904(b) of
Regulation S under the Securities Act and (iii) the transaction is not part of a plan or
scheme to evade the registration requirements of the Securities Act. Upon consummation of the
proposed transfer in accordance with the terms of the Indenture, the transferred beneficial
interest or Restricted Definitive Note will be subject to the restrictions on transfer
enumerated in the Private Placement Legend printed on the Restricted Global Note and/or the
Restricted Definitive Note and in the Indenture and the Securities Act.

	3.	 	o Check and complete if Transferee will take delivery of a beneficial interest in
a Definitive Note pursuant to any provision of the Securities Act other than Rule 144A or
Regulation S. The Transfer is being effected in compliance with the transfer restrictions
applicable to beneficial interests in Restricted Global Notes and Restricted Definitive Notes
and pursuant to and in accordance with the Securities Act and any applicable blue sky
securities laws of any state of the United States, and accordingly the Transferor hereby
further certifies that (check one):

               (a) o such Transfer is being effected pursuant to and in accordance with Rule 144
under the Securities Act;

               or

               (b) o such Transfer is being effected to the Company or a subsidiary thereof;

               or

B-2

 

               (c) o such Transfer is being effected pursuant to an effective registration
statement under the Securities Act and in compliance with the prospectus delivery requirements of
the Securities Act.

	4.	 	o Check if Transferee will take delivery of a beneficial interest in an
Unrestricted Global Note or of an Unrestricted Definitive Note.

               (a) o Check if Transfer is pursuant to Rule 144. (i) The Transfer is being
effected pursuant to and in accordance with Rule 144 under the Securities Act and in compliance
with the transfer restrictions contained in the Indenture and any applicable blue sky securities
laws of any state of the United States and (ii) the restrictions on transfer contained in the
Indenture and the Private Placement Legend are not required in order to maintain compliance with
the Securities Act. Upon consummation of the proposed Transfer in accordance with the terms of the
Indenture, the transferred beneficial interest or Definitive Note will no longer be subject to the
restrictions on transfer enumerated in the Private Placement Legend printed on the Restricted
Global Notes, on Restricted Definitive Notes and in the Indenture.

               (b) o Check if Transfer is Pursuant to Regulation S. (i) The Transfer is being
effected pursuant to and in accordance with Rule 903 or Rule 904 under the Securities Act and in
compliance with the transfer restrictions contained in the Indenture and any applicable blue sky
securities laws of any state of the United States and (ii) the restrictions on transfer contained
in the Indenture and the Private Placement Legend are not required in order to maintain compliance
with the Securities Act. Upon consummation of the proposed Transfer in accordance with the terms
of the Indenture, the transferred beneficial interest or Definitive Note will no longer be subject
to the restrictions on transfer enumerated in the Private Placement Legend printed on the
Restricted Global Notes, on Restricted Definitive Notes and in the Indenture.

               (c) o Check if Transfer is Pursuant to Other Exemption. (i) The Transfer is being
effected pursuant to and in compliance with an exemption from the registration requirements of the
Securities Act other than Rule 144, Rule 903 or Rule 904 and in compliance with the transfer
restrictions contained in the Indenture and any applicable blue sky securities laws of any State of
the United States and (ii) the restrictions on transfer contained in the Indenture and the Private
Placement Legend are not required in order to maintain compliance with the Securities Act. Upon
consummation of the proposed Transfer in accordance with the terms of the Indenture, the
transferred beneficial interest or Definitive Note will not be subject to the restrictions on
transfer enumerated in the Private Placement Legend printed on the Restricted Global Notes or
Restricted Definitive Notes and in the Indenture.

     This certificate and the statements contained herein are made for your benefit and the benefit
of the Company.

B-3

 

	 	 	 	 	 
	 	[Insert Name of Transferor] 

 	 
	 	By:  	 	 
	 	 	Name:  	 	 
	Dated:                     , ______ 	 	Title:  	 	 
	 

B-4

 

ANNEX A TO CERTIFICATE OF TRANSFER

	 	1.	 	The Transferor owns and proposes to transfer the following:

[CHECK ONE OF (a) OR (b)]

	 	(a)	 	o a beneficial interest in the Restricted Global Note; or
	 
	 	(b)	 	o a Restricted Definitive Note.
	 
	 	2.	 	After the Transfer the Transferee will hold:

[CHECK ONE]

	 	(a)	 	a beneficial interest in the:

	 	(i)	 	o Restricted Global Note (CUSIP                     ), or
	 
	 	(ii)	 	o Unrestricted Global Note (CUSIP                     ); or

	 	(b)	 	o Restricted Definitive Note; or
	 
	 	(c)	 	o an Unrestricted Definitive Note,

     in accordance with the terms of the Indenture.

B-5

 

EXECUTION COPY

EXHIBIT C

[FORM OF CERTIFICATE OF EXCHANGE]

Wyeth

Five Giralda Farms

Madison, New Jersey 07940

Attention: Secretary of the Company

JPMorgan Chase Bank, N.A.

4 New York Plaza

15th Floor

New York, NY 10004

Attention: Worldwide Securities Services

     Re: •% Series A Notes due ___

     Reference is hereby made to the Indenture, dated as of April 10, 1992, as amended by the
Supplemental Indenture, dated as of October 13, 1992 and as further amended by the Sixth
Supplemental Indenture, date as of November 14, 2005 (as so amended and supplemented, the
"Indenture”), between Wyeth (as successor to American Home Products Corporation), a Delaware
corporation, as issuer (the “Company”), and JPMorgan Chase Bank, N.A. (as successor to
Manufacturers Hanover Trust Company), as trustee. Capitalized terms used but not defined herein
shall have the meanings given to them in the Indenture.

                         , (the “Owner”) owns and proposes to exchange the Note[s] or interest in such
Note[s] specified herein, in the principal amount of $                     in such Note[s] or interests
(the “Exchange”). In connection with the Exchange, the Owner hereby certifies that:

	1.	 	Exchange of Restricted Definitive Notes or Beneficial Interests in a Restricted Global
Note for Unrestricted Definitive Notes or Beneficial Interests in an Unrestricted Global
Note.

     (a) o Check if Exchange is from beneficial interest in a Restricted Global Note to
beneficial interest in an Unrestricted Global Note. In connection with the Exchange of the Owner’s
beneficial interest in a Restricted Global Note for a beneficial interest in an Unrestricted Global
Note in an equal principal amount, the Owner hereby certifies (i) the beneficial interest is being
acquired for the Owner’s own account without transfer, (ii) such Exchange has been effected in
compliance with the transfer restrictions applicable to the Global Notes and pursuant to and in
accordance with the United States Securities Act of 1933, as amended (the “Securities Act”), (iii)
the restrictions on transfer contained in the Indenture and the Private Placement Legend are not
required in order to maintain compliance with the Securities Act and (iv) the beneficial interest
in an Unrestricted Global Note is being acquired in compliance with any applicable blue sky
securities laws of any state of the United States.

     (b) o Check if Exchange is from beneficial interest in a Restricted Global Note to
Unrestricted Definitive Note. In connection with the Exchange of the Owner’s beneficial interest
in a Restricted Global Note for an Unrestricted Definitive Note, the Owner hereby certifies (i) the
Definitive Note is being acquired for the Owner’s own account without transfer, (ii) such Exchange

C-1

 

has been effected in compliance with the transfer restrictions applicable to the Restricted
Global Notes and pursuant to and in accordance with the Securities Act, (iii) the restrictions on
transfer contained in the Indenture and the Private Placement Legend are not required in order to
maintain compliance with the Securities Act and (iv) the Definitive Note is being acquired in
compliance with any applicable blue sky securities laws of any state of the United States.

     (c) o Check if Exchange is from Restricted Definitive Note to beneficial interest
in an Unrestricted Global Note. In connection with the Owner’s Exchange of a Restricted Definitive
Note for a beneficial interest in an Unrestricted Global Note, the Owner hereby certifies (i) the
beneficial interest is being acquired for the Owner’s own account without transfer, (ii) such
Exchange has been effected in compliance with the transfer restrictions applicable to Restricted
Definitive Notes and pursuant to and in accordance with the Securities Act, (iii) the restrictions
on transfer contained in the Indenture and the Private Placement Legend are not required in order
to maintain compliance with the Securities Act and (iv) the beneficial interest is being acquired
in compliance with any applicable blue sky securities laws of any state of the United States.

     (d) o Check if Exchange is from Restricted Definitive Note to Unrestricted
Definitive Note. In connection with the Owner’s Exchange of a Restricted Definitive Note for an
Unrestricted Definitive Note, the Owner hereby certifies (i) the Unrestricted Definitive Note is
being acquired for the Owner’s own account without transfer, (ii) such Exchange has been effected
in compliance with the transfer restrictions applicable to Restricted Definitive Notes and pursuant
to and in accordance with the Securities Act, (iii) the restrictions on transfer contained in the
Indenture and the Private Placement Legend are not required in order to maintain compliance with
the Securities Act and (iv) the Unrestricted Definitive Note is being acquired in compliance with
any applicable blue sky securities laws of any state of the United States.

	2.	 	Exchange of Restricted Definitive Notes or Beneficial Interests in Restricted Global
Notes for Restricted Definitive Notes or Beneficial Interests in Restricted Global Notes.

     (a) o Check if Exchange is from beneficial interest in a Restricted Global Note to
Restricted Definitive Note. In connection with the Exchange of the Owner’s beneficial interest in
a Restricted Global Note for a Restricted Definitive Note with an equal principal amount, the Owner
hereby certifies that the Restricted Definitive Note is being acquired for the Owner’s own account
without transfer. Upon consummation of the proposed Exchange in accordance with the terms of the
Indenture, the Restricted Definitive Note issued will continue to be subject to the restrictions on
transfer enumerated in the Private Placement Legend printed on the Restricted Definitive Note and
in the Indenture and the Securities Act.

     (b) o Check if Exchange is from Restricted Definitive Note to beneficial interest
in a Restricted Global Note. In connection with the Exchange of the Owner’s Restricted Definitive
Note for a beneficial interest in the Restricted Global Note, the Owner hereby certifies (1) the
beneficial interest is being acquired for the Owner’s own account without transfer and (ii) such
Exchange has been effected in compliance with the transfer restrictions applicable to the
Restricted Global Notes and pursuant to and in accordance with the Securities Act, and in
compliance with any applicable blue sky securities laws of any state of the United States. Upon
consummation of the proposed Exchange in accordance with the terms of the Indenture, the beneficial
interest issued will be subject to the

C-2

 

restrictions on transfer enumerated in the Private Placement Legend printed on the relevant
Restricted Global Note and in the Indenture and the Securities Act.

     This certificate and the statements contained herein are made for your benefit and the benefit
of the Company.

	 	 	 	 	 
	 	 

[Insert Name of Owner] 

 	 
	 	By:  	 	 
	 	 	Name:  	 	 
	 	 	Title:  	 	 
	 

Dated:                     , ______

C-3EX-4.4

 

Exhibit 4.4

Conformed Copy

EXECUTION COPY

$1,500,000,000

WYETH

$1,000,000,000 5.50% Notes Due 2016

$500,000,000 6.00% Notes Due 2036

EXCHANGE AND REGISTRATION RIGHTS AGREEMENT

November 14, 2005

J.P. Morgan Securities Inc.

Citigroup Global Markets Inc.

As Representatives of the several

Initial Purchasers

c/o J.P. Morgan Securities Inc.

277 Park Avenue

New York, New York 10172

Ladies and Gentlemen:

     
Wyeth, a Delaware corporation (the “Company”),
proposes to issue and sell to the several Initial Purchasers
listed in Schedule I to the Purchase Agreement (the
“Initial Purchasers”), upon the terms and
subject to the conditions set forth in a purchase agreement
dated November 8, 2005 between the Company and the Initial
Purchasers (the “Purchase Agreement”),
$1,000,000,000 aggregate principal amount of its
5.50% Notes due 2016 (the “2016 Notes”)
and $500,000,000 aggregate principal amount of its
6.00% Notes due 2036 (the “2036 Notes” and
collectively with the 2016 Notes, the “Notes”).
Capitalized terms used but not defined herein shall have the
meanings given to such terms in the Purchase Agreement.

     
As an inducement to the Initial Purchasers to enter into the
Purchase Agreement and in satisfaction of a condition to the
obligations of the Initial Purchasers thereunder, the Company
agrees with the Initial Purchasers, for the benefit of the
holders (including the Initial Purchasers) of the Notes, the
Exchange Notes (as defined herein) and the Private Exchange
Notes (as defined herein) (collectively, the
“Holders”), as follows:

     
1. Registered Exchange Offer. The Company shall
(i) prepare and, not later than 90 calendar days following
the date of original issuance of the Notes (the “Closing
Date”), use its reasonable best efforts to file with
the Commission a registration statement (the “Exchange
Offer Registration Statement”) on an appropriate form
under the Securities Act with respect to a proposed offer to the
Holders of the Notes (the “Registered Exchange
Offer”) to issue and deliver to such Holders, in
exchange for the Notes, debt securities of the Company (the
“Exchange Notes”) that have the same aggregate
principal amount as the tendered Notes and that are identical in
all material respects to the tendered Notes, except for the
transfer restrictions relating to the Notes, (ii) use its
reasonable best efforts to cause the Exchange Offer Registration
Statement to become effective under the Securities Act no later
than 180 calendar days after the Closing Date and the Registered
Exchange Offer to be consummated no later than 210 calendar days
after the Closing Date and (iii) keep the Exchange Offer
Registration Statement effective for not less than 30 calendar
days (or longer, if required by applicable law) after the date
on which notice of the Registered Exchange Offer is mailed to
the Holders (such period being called the “Exchange
Offer Registration Period”). The Notes will be issued
as separate series of debt securities under a supplemental

 

indenture (the “Supplemental Indenture”) to be
dated as of the date hereof between the Company and JPMorgan
Chase Bank, N.A. (as successor to Manufacturers Hanover Trust
Company, as trustee (the “Trustee”). The
Supplemental Indenture relates to an indenture dated as of
April 10, 1992, as amended on October 13, 1992,
between the Company and the Trustee (the “Base
Indenture”, and as further amended and supplemented by
the Supplemental Indenture, the “Indenture”).

     
Upon the effectiveness of the Exchange Offer Registration
Statement, the Company shall promptly commence the Registered
Exchange Offer, it being the objective of such Registered
Exchange Offer to enable each Holder electing to exchange Notes
for Exchange Notes (assuming that such Holder (a) is not an
affiliate of the Company or a Participating Broker-Dealer (as
defined herein) not complying with the requirements of the next
sentence, (b) is not an Initial Purchaser holding Notes
that have, or that are reasonably likely to have, the status of
an unsold allotment in an initial distribution,
(c) acquires the Exchange Notes in the ordinary course of
such Holder’s business and (d) has no arrangements or
understandings with any person to participate in the
distribution of the Exchange Notes) and to trade such Exchange
Notes from and after their receipt without any limitations or
restrictions under the Securities Act and without material
restrictions under the securities laws of the several states of
the United States. The Company, the Initial Purchasers and each
Participating Broker-Dealer acknowledge that, pursuant to
current interpretations by the Commission’s staff of
Section 5 of the Securities Act, each Holder that is a
broker-dealer electing to exchange Notes, acquired for its own
account as a result of market-making activities or other trading
activities, for Exchange Notes (a “Participating
Broker-Dealer”), is required to deliver a prospectus
containing substantially the information set forth in
Annex A hereto on the cover, in Annex B hereto in the
“Exchange Offer Procedures” section and the
“Purpose of the Exchange Offer” section and in
Annex C hereto in the “Plan of Distribution”
section of such prospectus in connection with a sale of any such
Exchange Notes received by such Participating Broker-Dealer
pursuant to the Registered Exchange Offer.

     
If, prior to the consummation of the Registered Exchange Offer,
any Holder holds any Notes acquired by it that have, or that are
reasonably likely to be determined to have, the status of an
unsold allotment in an initial distribution, or any Holder is
not entitled to participate in the Registered Exchange Offer,
the Company shall, upon the request of any such Holder,
simultaneously with the delivery of the Exchange Notes in the
Registered Exchange Offer, issue and deliver to any such Holder,
in exchange for the Notes held by such Holder (the
“Private Exchange”), a like aggregate principal
amount of debt securities of the Company (the “Private
Exchange Notes”) that are identical in all material
respects to the Exchange Notes, except for the transfer
restrictions relating to such Private Exchange Notes. The
Private Exchange Notes will be issued under the same indenture
as the Exchange Notes, and the Company shall use its reasonable
best efforts to cause the Private Exchange Notes to bear the
same CUSIP number as the Exchange Notes.

     
In connection with the Registered Exchange Offer, the Company
shall:

		
	 	     
    (a) mail to each Holder a copy of the prospectus forming
    part of the Exchange Offer Registration Statement, together with
    an appropriate letter of transmittal and related documents;
	 
	 	     
    (b) keep the Registered Exchange Offer open for not less
    than 30 calendar days (or longer, if required by applicable law)
    after the date on which notice of the Registered Exchange Offer
    is mailed to the Holders;
	 
	 	     
    (c) utilize the services of a depositary for the Registered
    Exchange Offer with an address in the Borough of Manhattan, The
    City of New York;
	 
	 	     
    (d) permit Holders to withdraw tendered Notes at any time
    prior to the close of business, New York City time, on the last
    business day on which the Registered Exchange Offer shall remain
    open; and
	 
	 	     
    (e) otherwise comply in all respects with all laws that are
    applicable to the Registered Exchange Offer.

2

 

     
As soon as practicable after the close of the Registered
Exchange Offer and any Private Exchange, as the case may be, the
Company shall:

		
	 	     
    (a) accept for exchange all Notes tendered and not validly
    withdrawn pursuant to the Registered Exchange Offer and the
    Private Exchange;
	 
	 	     
    (b) deliver to the Trustee for cancellation all Notes so
    accepted for exchange; and
	 
	 	     
    (c) cause the Trustee promptly to authenticate and deliver
    to each Holder, Exchange Notes or Private Exchange Notes, as the
    case may be, equal in principal amount to the Notes of such
    Holder so accepted for exchange.

     
The Company shall use its reasonable best efforts to keep the
Exchange Offer Registration Statement effective and to amend and
supplement the prospectus contained therein in order to permit
such prospectus to be used by all persons subject to the
prospectus delivery requirements of the Securities Act for such
period of time as such persons must comply with such
requirements in order to resell the Exchange Notes; provided
that (i) in the case where such prospectus and any
amendment or supplement thereto must be delivered by a
Participating Broker-Dealer, such period shall be the lesser of
180 calendar days and the date on which all Participating
Broker-Dealers have sold all Exchange Notes held by them and
(ii) the Company shall make such prospectus and any
amendment or supplement thereto available to any broker-dealer
for use in connection with any resale of any Exchange Notes for
a period of not less than 90 calendar days after the
consummation of the Registered Exchange Offer.

     
The Indenture shall provide that the Notes, the Exchange Notes
and the Private Exchange Notes of a specified maturity shall
vote and consent together on all matters as one class where a
class vote is required and that none of the Notes, the Exchange
Notes or the Private Exchange Notes of a specified maturity will
have the right to vote or consent as a separate class on any
matter.

     
Interest on each Exchange Note and Private Exchange Note issued
pursuant to the Registered Exchange Offer and in the Private
Exchange will accrue from the last interest payment date on
which interest was paid on the Notes surrendered in exchange
therefor or, if no interest has been paid on the Notes, from the
date of original issuance of such Notes.

     
Each Holder participating in the Registered Exchange Offer shall
be required to represent to the Company that at the time of the
consummation of the Registered Exchange Offer (i) any
Exchange Notes received by such Holder will be acquired in the
ordinary course of business, (ii) such Holder will have no
arrangements or understanding with any person to participate in
the distribution of the Notes or the Exchange Notes within the
meaning of the Securities Act and (iii) such Holder is not
an affiliate of the Company or, if it is such an affiliate, such
Holder will comply with the registration and prospectus delivery
requirements of the Securities Act to the extent applicable.

     
Notwithstanding any other provisions hereof, the Company will
ensure that (i) any Exchange Offer Registration Statement
and any amendment thereto and any prospectus forming part
thereof and any supplement thereto complies in all material
respects with the Securities Act and the rules and regulations
of the Commission thereunder, (ii) any Exchange Offer
Registration Statement and any amendment thereto does not, when
it becomes effective, contain an untrue statement of a material
fact or omit to state a material fact required to be stated
therein or necessary to make the statements therein not
misleading and (iii) any prospectus forming part of any
Exchange Offer Registration Statement, and any supplement to
such prospectus, does not, as of the consummation of the
Registered Exchange Offer, include an untrue statement of a
material fact or omit to state a material fact necessary in
order to make the statements therein, in the light of the
circumstances under which they were made, not misleading.

     
2. Shelf Registration. If (i) because of any
change in law or applicable interpretations thereof by the
Commission’s staff, the Company is not permitted to effect
the Registered Exchange Offer as contemplated by Section 1
hereof, or (ii) the Registered Exchange Offer is not
consummated within 210 calendar days after the Closing Date, or
(iii) within 90 days after the consummation of the
Registered Exchange Offer any Initial Purchaser so requests with
respect to Notes or Private Exchange Notes not

3

 

eligible to be exchanged for Exchange Notes in the Registered
Exchange Offer and held by it following the consummation of the
Registered Exchange Offer, or (iv) any Holder that
participates in the Registered Exchange Offer does not receive
freely transferable Exchange Notes in exchange for tendered
Notes (other than due solely to such Holder being an affiliate
of the Company or a Participating Broker-Dealer and not
complying with the prospectus delivery requirements of the
second paragraph of Section 1 above), or (v) the
Company so elects, then the following provisions shall apply:

		
	 	     
    (a) The Company shall use its reasonable best efforts to
    file as promptly as practicable (but in no event more than 45
    calendar days after so required or requested pursuant to this
    Section 2) with the Commission, and thereafter shall use
    its reasonable best efforts to cause to be declared effective, a
    shelf registration statement on an appropriate form under the
    Securities Act relating to the offer and sale of the Transfer
    Restricted Notes (as defined below) by the Holders thereof from
    time to time in accordance with the methods of distribution set
    forth in such registration statement (hereafter, a
    “Shelf Registration Statement” and, together
    with any Exchange Offer Registration Statement, a
    “Registration Statement”).
	 
	 	     
    (b) The Company shall use its reasonable best efforts to
    keep the Shelf Registration Statement continuously effective in
    order to permit the prospectus forming part thereof to be used
    by Holders of Transfer Restricted Notes for a period ending on
    the earlier of (i) two years from the Closing Date or such
    shorter period that will terminate when all the Transfer
    Restricted Notes covered by the Shelf Registration Statement
    have been sold pursuant thereto and (ii) the date on which
    the Notes become eligible for resale without volume restrictions
    pursuant to Rule 144 under the Securities Act (in any such
    case, such period being called the “Shelf Registration
    Period”). The Company shall be deemed not to have used
    its reasonable best efforts to keep the Shelf Registration
    Statement effective during the requisite period if it
    voluntarily takes any action that would result in Holders of
    Transfer Restricted Notes covered thereby not being able to
    offer and sell such Transfer Restricted Notes during that
    period, unless such action is required by applicable law. If the
    Company fails to keep the Shelf Registration continuously
    effective or useable for resales due to any of the circumstances
    referenced in clauses (v) or (vi) of
    Section 4(b), the period referenced in clause (i) of
    this Section 2(b) (or the period during which the
    Participating Broker-Dealers are entitled to use the prospectus
    included in an Exchange Offer Registration Statement in
    connection with the resale of Exchange Notes as provided in
    Section 1), will be extended by the number of days during
    the period from and including the date of the giving of notice
    pursuant to Section 4(b) to and including the date when
    holders will have received copies of the supplemented or amended
    prospectus necessary to permit resales of the notes or to and
    including the date on which the Company gives notice that the
    sale of the Notes may be resumed, as the case may be.
	 
	 	     
    (c) Notwithstanding any other provisions hereof, the
    Company will ensure that (i) any Shelf Registration
    Statement and any amendment thereto and any prospectus forming
    part thereof and any supplement thereto complies in all material
    respects with the Securities Act and the rules and regulations
    of the Commission thereunder, (ii) any Shelf Registration
    Statement and any amendment thereto (in either case, other than
    with respect to information included therein in reliance upon or
    in conformity with written information furnished to the Company
    by or on behalf of any Holder specifically for use therein (the
    “Holders’ Information”)) does not contain
    an untrue statement of a material fact or omit to state a
    material fact required to be stated therein or necessary to make
    the statements therein not misleading and (iii) any
    prospectus forming part of any Shelf Registration Statement, and
    any supplement to such prospectus (in either case, other than
    with respect to Holders’ Information), does not include an
    untrue statement of a material fact or omit to state a material
    fact necessary in order to make the statements therein, in the
    light of the circumstances under which they were made, not
    misleading.

     
3. Liquidated Damages. (a) The parties hereto
agree that the Holders of Transfer Restricted Notes will suffer
damages if the Company fails to fulfill its obligations under
Section 1 or Section 2, as applicable, and that it
would not be feasible to ascertain the extent of such damages.
Accordingly, if (i) the Exchange Offer Registration
Statement is not filed with the Commission on or prior to 90
calendar

4

 

days after the Closing Date, (ii) the Exchange Offer
Registration Statement is not declared effective within 180
calendar days after the Closing Date, (iii) the Registered
Exchange Offer is not consummated or the Shelf Registration
Statement is not declared effective on or prior to 210 calendar
days after the Closing Date, or (iv) the Shelf Registration
Statement is filed and declared effective within 180 calendar
days after the Closing Date (or in the case of a Shelf
Registration Statement required to be filed in response to a
change in law or the applicable interpretations of
Commission’s staff, if later, within 90 calendar days after
publication of the change in law or interpretation) but shall
thereafter cease to be effective or useable for resales due to
circumstances identified in clauses (v) or (vi) of
Section 4(b), and such failure continues for more than
60 days (whether or not consecutive) in any twelve month
period (each such event referred to above in clauses (i)
through (iv) of this Section 3(a), a
“Registration Default”), the Company will be
obligated to pay a special interest premium (the
“Special Interest Premium”) as liquidated
damages to each Holder of Transfer Restricted Notes, during the
period of one or more such Registration Defaults, in an amount
equal to 0.25% per annum on the principal amount of
Transfer Restricted Notes held by such Holder until (i) the
applicable Registration Statement is filed, (ii) the
Exchange Offer Registration Statement is declared effective,
(iii) the Registered Exchange Offer is consummated or the
Shelf Registration Statement is declared effective, or
(iv) the Shelf Registration Statement again becomes
effective or usable, as the case may be; provided,
however, that the aggregate amount of Special Interest
Premium payable in respect of any Note pursuant this
Section 3(a) shall not exceed 0.25% per annum and
provided, further, that the accrual of Special Interest Premium
on any Note will cease immediately upon the cure of all
Registration Defaults. As used herein, the term
“Transfer Restricted Notes” means (i) each
Note until the date on which such Note has been exchanged for a
freely transferable Exchange Note in the Registered Exchange
Offer, (ii) each Note or Private Exchange Note until the
date on which it has been effectively registered under the
Securities Act and disposed of in accordance with the Shelf
Registration Statement or (iii) each Note or Private
Exchange Note until the date on which it is distributed to the
public pursuant to Rule 144 under the Securities Act or is
saleable pursuant to Rule 144(k) under the Securities Act.
Notwithstanding anything to the contrary in this
Section 3(a), the Company shall not be required to pay
liquidated damages to a Holder of Transfer Restricted Notes if
such Holder failed to comply with its obligations to make the
representations set forth in the second to last paragraph of
Section 1 or failed to provide the information required to
be provided by it, if any, pursuant to Section 4(n).

     
(b) The Company shall notify the Trustee and the Paying
Agent under the Indenture immediately upon the happening of each
and every Registration Default. The Company shall pay the
liquidated damages due on the Transfer Restricted Notes by
depositing with the Paying Agent, in trust, for the benefit of
the Holders thereof, prior to 10:00 a.m., New York City
time, on the next interest payment date specified by the
Indenture and the Notes, sums sufficient to pay the liquidated
damages then due. The liquidated damages due shall be payable on
each interest payment date specified by the Indenture and the
Notes to the record holder entitled to receive the interest
payment to be made on such date. Each obligation to pay
liquidated damages shall be deemed to accrue from and including
the date of the applicable Registration Default.

     
(c) The parties hereto agree that the liquidated damages
provided for in this Section 3 constitute a reasonable
estimate of and are intended to constitute the sole damages that
will be suffered by Holders of Transfer Restricted Notes by
reason of the failure of (i) the Shelf Registration
Statement or the Exchange Offer Registration Statement to be
filed, (ii) the Shelf Registration Statement to remain
effective or (iii) the Exchange Offer Registration
Statement to be declared effective and the Registered Exchange
Offer to be consummated, in each case to the extent required by
this Agreement.

     
4. Registration Procedures. In connection with any
Registration Statement, the following provisions shall apply:

		
	 	     
    (a) The Company shall (i) furnish to each Initial
    Purchaser, prior to the filing thereof with the Commission, a
    copy of the Registration Statement and each amendment thereof
    and each supplement, if any, to the prospectus included therein
    and shall use its reasonable best efforts to reflect in each
    such document, when so filed with the Commission, such comments
    as any Initial

5

 

		
	 	
    Purchaser may reasonably propose; (ii) include the
    information set forth in Annex A hereto on the cover, in
    Annex B hereto in the “Exchange Offer Procedures”
    section and the “Purpose of the Exchange Offer”
    section and in Annex C hereto in the “Plan of
    Distribution” section of the prospectus forming a part of
    the Exchange Offer Registration Statement, and include the
    information set forth in Annex D hereto in the Letter of
    Transmittal delivered pursuant to the Registered Exchange Offer;
    and (iii) if requested by any Initial Purchaser, include
    the information required by Items 507 or 508 of
    Regulation S-K, as applicable, in the prospectus forming a
    part of the Exchange Offer Registration Statement.
	 
	 	     
    (b) The Company shall advise each Initial Purchaser, each
    Participating Broker-Dealer and the Holders (if applicable) and,
    if requested by any such person, confirm such advice in writing
    (which advice pursuant to clauses (ii)-(vi) hereof shall be
    accompanied by an instruction to suspend the use of the
    prospectus until the requisite changes have been made):

		
	 	     
    (i) when any Registration Statement and any amendment
    thereto has been filed with the Commission and when such
    Registration Statement or any post-effective amendment thereto
    has become effective;
	 
	 	     
    (ii) of any request by the Commission for amendments or
    supplements to any Registration Statement or the prospectus
    included therein or for additional information;
	 
	 	     
    (iii) of the issuance by the Commission of any stop order
    suspending the effectiveness of any Registration Statement or
    the initiation of any proceedings for that purpose;
	 
	 	     
    (iv) of the receipt by the Company of any notification with
    respect to the suspension of the qualification of the Notes, the
    Exchange Notes or the Private Exchange Notes for sale in any
    jurisdiction or the initiation or threatening of any proceeding
    for such purpose;
	 
	 	     
    (v) of the happening of any event that requires the making
    of any changes in any Registration Statement or the prospectus
    included therein in order that the statements therein are not
    misleading and do not omit to state a material fact required to
    be stated therein or necessary to make the statements therein
    not misleading; and
	 
	 	     
    (vi) in the case that a Shelf Registration Statement is
    filed and declared effective pursuant to Section 2, upon
    the occurrence or existence of any pending corporate
    development, public filing with the SEC or any other material
    event not listed in clauses (i)-(v) of this
    Section 4(b) that, in the reasonable judgment of the
    Company, makes it appropriate to suspend the availability of the
    Shelf Registration Statement and any related prospectus.

		
	 	     
    (c) The Company will make every reasonable effort to obtain
    the withdrawal at the earliest possible time of any order
    suspending the effectiveness of any Registration Statement.
	 
	 	     
    (d) The Company will furnish to each Holder of Transfer
    Restricted Notes included within the coverage of any Shelf
    Registration Statement, without charge, at least one conformed
    copy of such Shelf Registration Statement and any post-effective
    amendment thereto, including financial statements and schedules
    and, if any such Holder so requests in writing, all exhibits
    thereto (including those, if any, incorporated by reference).
	 
	 	     
    (e) The Company will, during the Shelf Registration Period,
    promptly deliver to each Holder of Transfer Restricted Notes
    included within the coverage of any Shelf Registration
    Statement, without charge, as many copies of the prospectus
    (including each preliminary prospectus) included in such Shelf
    Registration Statement and any amendment or supplement thereto
    as such Holder may reasonably request; and the Company consents
    to the use of such prospectus or any amendment or supplement
    thereto by each of the selling Holders of Transfer Restricted
    Notes in connection with the offer and sale of the Transfer
    Restricted Notes covered by such prospectus or any amendment or
    supplement thereto.

6

 

		
	 	     
    (f) The Company will furnish to each Initial Purchaser and
    each Participating Broker-Dealer, and to any other Holder who so
    requests, without charge, at least one conformed copy of the
    Exchange Offer Registration Statement and any post-effective
    amendment thereto, including financial statements and schedules
    and, if any Initial Purchaser or Participating Broker-Dealer or
    any such Holder so requests in writing, all exhibits thereto
    (including those, if any, incorporated by reference).
	 
	 	     
    (g) The Company will, during the Exchange Offer
    Registration Period or the Shelf Registration Period, as
    applicable, promptly deliver to each Initial Purchaser, each
    Participating Broker-Dealer and such other persons that are
    required to deliver a prospectus following the Registered
    Exchange Offer, without charge, as many copies of the final
    prospectus included in the Exchange Offer Registration Statement
    or the Shelf Registration Statement and any amendment or
    supplement thereto as such Initial Purchaser, Participating
    Broker-Dealer or other persons may reasonably request; and the
    Company consents to the use of such prospectus or any amendment
    or supplement thereto by any such Initial Purchaser,
    Participating Broker-Dealer or other persons, as applicable, as
    aforesaid.
	 
	 	     
    (h) Prior to the effective date of any Registration
    Statement, the Company will use its reasonable best efforts to
    register or qualify, or cooperate with the Holders of Notes,
    Exchange Notes or Private Exchange Notes included therein and
    their respective counsel in connection with the registration or
    qualification of, such Notes, Exchange Notes or Private Exchange
    Notes for offer and sale under the Notes or blue sky laws of
    such jurisdictions as any such Holder reasonably requests in
    writing and do any and all other acts or things necessary or
    advisable to enable the offer and sale in such jurisdictions of
    the Notes, Exchange Notes or Private Exchange Notes covered by
    such Registration Statement; provided that the Company will not
    be required to qualify generally to do business in any
    jurisdiction where it is not then so qualified or to take any
    action which would subject it to general service of process or
    to taxation in any such jurisdiction where it is not then so
    subject.
	 
	 	     
    (i) The Company will cooperate with the Holders of Notes,
    Exchange Notes or Private Exchange Notes to facilitate the
    timely preparation and delivery of certificates representing
    Notes, Exchange Notes or Private Exchange Notes to be sold
    pursuant to any Registration Statement free of any restrictive
    legends and in such denominations and registered in such names
    as the Holders thereof may request in writing prior to sales of
    Notes, Exchange Notes or Private Exchange Notes pursuant to such
    Registration Statement.
	 
	 	     
    (j) If any event contemplated by Section 4(b)(ii)
    through (vi) occurs during the period for which the Company
    is required to maintain an effective Registration Statement, the
    Company will promptly prepare and file with the Commission a
    post-effective amendment to the Registration Statement or a
    supplement to the related prospectus or file any other required
    document so that, as thereafter delivered to purchasers of the
    Notes, Exchange Notes or Private Exchange Notes from a Holder,
    the prospectus will not include an untrue statement of a
    material fact or omit to state a material fact necessary in
    order to make the statements therein, in the light of the
    circumstances under which they were made, not misleading.
	 
	 	     
    (k) Not later than the effective date of the applicable
    Registration Statement, the Company will provide CUSIP numbers
    for the Notes, the Exchange Notes and the Private Exchange
    Notes, as the case may be, and provide the Trustee with printed
    certificates for the Notes, the Exchange Notes or the Private
    Exchange Notes, as the case may be, in a form eligible for
    deposit with The Depository Trust Company.
	 
	 	     
    (l) The Company will comply with all applicable rules and
    regulations of the Commission and will make generally available
    to its security holders as soon as practicable after the
    effective date of the applicable Registration Statement an
    earning statement satisfying the provisions of
    Section 11(a) of the Securities Act; provided that in no
    event shall such earning statement be delivered later than 45
    calendar days after the end of a 12-month period (or 90 calendar
    days, if such period is a fiscal year) beginning with the first
    month of the Company’s first fiscal quarter commencing
    after the effective date of the applicable Registration
    Statement, which statement shall cover such 12-month period.

7

 

		
	 	     
    (m) The Company will cause the Indenture to be qualified
    under the Trust Indenture Act as required by applicable law in a
    timely manner.
	 
	 	     
    (n) The Company may require each Holder of Transfer
    Restricted Notes to be registered pursuant to any Shelf
    Registration Statement to furnish to the Company such
    information concerning the Holder and the distribution of such
    Transfer Restricted Notes as the Company may from time to time
    reasonably require for inclusion in such Shelf Registration
    Statement, and the Company may exclude from such registration
    the Transfer Restricted Notes of any Holder that fails to
    furnish such information within a reasonable time after
    receiving such request.
	 
	 	     
    (o) In the case of a Shelf Registration Statement, each
    Holder of Transfer Restricted Notes to be registered pursuant
    thereto agrees by acquisition of such Transfer Restricted Notes
    that, upon receipt of any notice from the Company pursuant to
    Section 4(b)(ii) through (vi), such Holder will discontinue
    disposition of such Transfer Restricted Notes until such
    Holder’s receipt of copies of the supplemental or amended
    prospectus contemplated by Section 4(j) or until advised in
    writing (the “Advice”) by the Company that the
    use of the applicable prospectus may be resumed. If the Company
    shall give any notice under Section 4(b)(ii) through
    (vi) during the period that the Company is required to
    maintain an effective Registration Statement (the
    “Effectiveness Period”), such Effectiveness
    Period shall be extended by the number of days during such
    period from and including the date of the giving of such notice
    to and including the date when each seller of Transfer
    Restricted Notes covered by such Registration Statement shall
    have received (x) the copies of the supplemental or amended
    prospectus contemplated by Section 4(j) (if an amended or
    supplemental prospectus is required) or (y) the Advice (if
    no amended or supplemental prospectus is required).
	 
	 	     
    (p) In the case of a Shelf Registration Statement, the
    Company shall enter into such customary agreements (including,
    if requested, an underwriting agreement in customary form) and
    take all such other action, if any, as Holders of a majority in
    aggregate principal amount of the Notes, Exchange Notes and
    Private Exchange Notes being sold or the managing underwriters
    (if any) shall reasonably request in order to facilitate any
    disposition of Notes, Exchange Notes or Private Exchange Notes
    pursuant to such Shelf Registration Statement.
	 
	 	     
    (q) In the case of a Shelf Registration Statement, the
    Company shall (i) make reasonably available for inspection
    by a representative of, and Special Counsel (as defined below)
    acting for, Holders of a majority in aggregate principal amount
    of the Notes, Exchange Notes and Private Exchange Notes being
    sold and any underwriter participating in any disposition of
    Notes, Exchange Notes or Private Exchange Notes pursuant to such
    Shelf Registration Statement, all relevant financial and other
    records, pertinent corporate documents and properties of the
    Company and its subsidiaries and (ii) use its reasonable
    best efforts to have its officers, directors, employees,
    accountants and counsel supply all relevant information
    reasonably requested by such representative, Special Counsel or
    any such underwriter (an “Inspector”) in
    connection with such Shelf Registration Statement.
	 
	 	     
    (r) In the case of a Shelf Registration Statement, the
    Company shall, if requested by Holders of a majority in
    aggregate principal amount of the Notes, Exchange Notes and
    Private Exchange Notes being sold, their Special Counsel or the
    managing underwriters (if any) in connection with such Shelf
    Registration Statement, use its reasonable best efforts to cause
    (i) its counsel to deliver an opinion relating to the Shelf
    Registration Statement and the Notes, Exchange Notes or Private
    Exchange Notes, as applicable, in customary form, (ii) its
    officers to execute and deliver all customary documents and
    certificates requested by Holders of a majority in aggregate
    principal amount of the Notes, Exchange Notes and Private
    Exchange Notes being sold, their Special Counsel or the managing
    underwriters (if any) and (iii) its independent public
    accountants to provide a comfort letter or letters in customary
    form, subject to receipt of appropriate documentation as
    contemplated, and only if permitted, by Statement of Auditing
    Standards No. 72.

     
5. Registration Expenses. The Company will bear all
expenses incurred in connection with the performance of its
obligations under Sections 1, 2, 3 and 4 and the
Company will reimburse the Initial Purchasers and the Holders
for the reasonable fees and disbursements of one firm of
attorneys (in addition

8

 

to any local counsel) chosen by the Holders of a majority in
aggregate principal amount of the Notes, the Exchange Notes and
the Private Exchange Notes to be sold pursuant to each
Registration Statement (the “Special Counsel”)
acting for the Initial Purchasers or Holders in connection
therewith.

     
6. Indemnification and Contribution. In the event of
a Shelf Registration Statement or in connection with any
prospectus delivery pursuant to an Exchange Offer Registration
Statement by an Initial Purchaser or Participating
Broker-Dealer, as applicable, the Company shall indemnify and
hold harmless each Holder (including, without limitation, any
such Initial Purchaser or Participating Broker-Dealer) and each
person, if any, who controls such Holder within the meaning of
the Securities Act or the Exchange Act (collectively referred to
for purposes of this Section 6 as a Holder) from and
against any and all losses, claims, damages and liabilities
(including, without limitation, any loss, claim, damage or
liability relating to purchases and sales of Notes, Exchange
Notes or Private Exchange Notes) caused by (i) any untrue
statement or alleged untrue statement of a material fact
contained in any such Registration Statement or any prospectus
forming part thereof or in any amendment or supplement thereto
or (ii) the omission or alleged omission to state therein a
material fact required to be stated therein or necessary in
order to make the statements therein, in the light of the
circumstances under which they were made, not misleading;
provided, however, that the Company shall not be liable
in any such case to the extent that any such loss, claim,
damage, liability or action arises out of, or is based upon, an
untrue statement or alleged untrue statement in or omission or
alleged omission from any of such documents in reliance upon and
in conformity with any Holders’ Information; and provided,
further, that with respect to any such untrue statement in or
omission from any related preliminary prospectus, the indemnity
agreement contained in this Section 6 shall not inure to
the benefit of any Holder from whom the person asserting any
such loss, claim, damage, liability or action received Notes,
Exchange Notes or Private Exchange Notes to the extent that such
loss, claim, damage, liability or action of or with respect to
such Holder results from the fact that both (A) a copy of
the final prospectus was not sent or given to such person at or
prior to the written confirmation of the sale of such Notes,
Exchange Notes or Private Exchange Notes to such person and
(B) the untrue statement in or omission from the related
preliminary prospectus was corrected in the final prospectus
unless, in either case, such failure to deliver the final
prospectus was a result of non-compliance by the Company with
Section 4(d), 4(e), 4(f) or 4(g).

     
In the event of a Shelf Registration statement, each Holder
agrees, severally and not jointly, to indemnify and hold
harmless the Company, its directors, its officers who sign the
Registration Statement thereto and each person, if any, who
controls the Company within the meaning of either the Securities
Act or the Exchange Act to the same extent as the foregoing
indemnity from the Company to such Holder, but only with
reference to information relating to such Holder furnished to
the Company by such Holder in writing expressly for use in any
such Registration Statement and any prospectus or any amendments
or supplements thereto.

     
In case any proceeding (including any governmental
investigation) shall be instituted involving any person in
respect of which indemnity may be sought pursuant to either of
the two preceding paragraphs, such person (the
“indemnified party”) shall promptly notify the
person against whom such indemnity may be sought (the
“indemnifying party”) in writing and the
indemnifying party, upon request of the indemnified party, shall
retain counsel reasonably satisfactory to the indemnified party
to represent the indemnified party and any others the
indemnifying party may designate in such proceeding and shall
pay the fees and disbursements of such counsel related to such
proceeding. In any such proceeding, any indemnified party shall
have the right to retain its own counsel, but the fees and
expenses of such counsel shall be at the expense of such
indemnified party unless (i) the indemnifying party and the
indemnified party shall have mutually agreed to the retention of
such counsel or (ii) the named parties to any such
proceeding (including any impleaded parties) include both the
indemnifying party and the indemnified party and representation
of both parties by the same counsel would be inappropriate due
to actual or potential conflicting interests between them. It is
understood that the indemnifying party shall not, in respect of
the legal expenses of any indemnified party in connection with
any proceeding or related proceedings in the same jurisdiction,
be liable for the fees and expenses of more than one separate
firm (in addition to any local counsel) for all such indemnified
parties and that all such fees and expenses shall be

9

 

reimbursed as they are incurred. Such firm shall be designated
in writing by the indemnified parties, in the case of parties
indemnified pursuant to the second preceding paragraph, and by
the Company, in the case of parties indemnified pursuant to the
first preceding paragraph. The indemnifying party shall not be
liable for any settlement of any proceeding effected without its
written consent, but if settled with such consent or if there be
a final judgment for the plaintiff, the indemnifying party
agrees to indemnify the indemnified party from and against any
loss or liability by reason of such settlement or judgment. No
indemnifying party shall, without the prior written consent of
the indemnified party, effect any settlement of any pending or
threatened proceeding in respect of which any indemnified party
is or could have been a party and indemnity could have been
sought hereunder by such indemnified party, unless such
settlement includes an unconditional release of such indemnified
party from all liability on claims that are the subject matter
of such proceeding.

     
If the indemnification provided for in this Section 6 is
unavailable or insufficient to hold harmless an indemnified
party in respect of any losses, claims, damages or liabilities
referred to therein, then each indemnifying party shall, in lieu
of indemnifying such indemnified party, contribute to the amount
paid or payable by such indemnified party as a result of such
loss, claim, damage or liability (i) in such proportion as
shall be appropriate to reflect the relative benefits received
by the Company from the offering and sale of the Notes, on the
one hand, and a Holder with respect to the sale by such Holder
of Notes, Exchange Notes or Private Exchange Notes, on the
other, or (ii) if the allocation provided by
clause (i) above is not permitted by applicable law, in
such proportion as is appropriate to reflect not only the
relative benefits referred to in clause (i) above but also
the relative fault of the Company on the one hand and such
Holder on the other with respect to the statements or omissions
that resulted in such loss, claim, damage or liability, as well
as any other relevant equitable considerations. The relative
benefits received by the Company on the one hand and a Holder on
the other with respect to such offering and such sale shall be
deemed to be in the same proportion as the total net proceeds
from the offering of the Notes (before deducting expenses)
received by or on behalf of the Company as set forth in
Section 1 of the Purchase Agreement, on the one hand, bear
to the total proceeds received by such Holder with respect to
its sale of Notes, Exchange Notes or Private Exchange Notes, on
the other. The relative fault shall be determined by reference
to, among other things, whether the untrue or alleged untrue
statement of a material fact or the omission or alleged omission
to state a material fact relates to the Company or information
supplied by the Company on the one hand or to any Holders’
Information supplied by such Holder on the other, the intent of
the parties and their relative knowledge, access to information
and opportunity to correct or prevent such untrue statement or
omission. The parties hereto agree that it would not be just and
equitable if contributions pursuant to this Section 6 were
to be determined by pro rata allocation or by any other method
of allocation that does not take into account the equitable
considerations referred to herein. The amount paid or payable by
an indemnified party as a result of the loss, claim, damage or
liability in respect thereof, referred to above in this
Section 6 shall be deemed to include, for purposes of this
Section 6, any legal or other expenses reasonably incurred
by such indemnified party in connection with investigating or
defending or preparing to defend any such action or claim.
Notwithstanding the provisions of this Section 6, an
indemnifying party that is a Holder of Notes, Exchange Notes or
Private Exchange Notes shall not be required to contribute any
amount in excess of the amount by which the total price at which
the Notes, Exchange Notes or Private Exchange Notes sold by such
indemnifying party to any purchaser exceeds the amount of any
damages which such indemnifying party has otherwise paid or
become liable to pay by reason of any untrue or alleged untrue
statement or omission or alleged omission. No person guilty of
fraudulent misrepresentation (within the meaning of
Section 11(f) of the Securities Act) shall be entitled to
contribution from any person who was not guilty of such
fraudulent misrepresentation.

     
The indemnity and contribution provisions contained in this
Section 6 and the representations and warranties of the
Company contained herein shall remain operative and in full
force and effect regardless of (i) any termination of this
Agreement, (ii) any investigation made by or on behalf of
any Holder or any person controlling any Holder or by or on
behalf of the Company, its directors or officers or any person
controlling the Company and (iii) acceptance of and payment
for any of the Notes, Exchange Notes or Private Exchange Notes.

10

 

     
7. Rules 144 and 144A. The Company shall use
its reasonable best efforts to file the reports required to be
filed by it under the Securities Act and the Exchange Act in a
timely manner and, if at any time the Company is not required to
file such reports, it will, upon the written request of any
Holder of Transfer Restricted Notes, make publicly available
other information so long as necessary to permit sales of such
Holder’s securities pursuant to Rules 144 and 144A.
The Company covenants that it will take such further action as
any Holder of Transfer Restricted Notes may reasonably request,
all to the extent required from time to time to enable such
Holder to sell Transfer Restricted Notes without registration
under the Securities Act within the limitation of the exemptions
provided by Rules 144 and 144A (including, without
limitation, the requirements of Rule 144A(d)(4)). Upon the
written request of any Holder of Transfer Restricted Notes, the
Company shall deliver to such Holder a written statement as to
whether it has complied with such requirements. Notwithstanding
the foregoing, nothing in this Section 7 shall be deemed to
require the Company to register any of its securities pursuant
to the Exchange Act.

     
8. Underwritten Registrations. If any of the
Transfer Restricted Notes covered by any Shelf Registration
Statement are to be sold in an underwritten offering, the
investment banker or investment bankers and manager or managers
that will administer the offering will be selected by the
Holders of a majority in aggregate principal amount of such
Transfer Restricted Notes included in such offering, subject to
the consent of the Company (which shall not be unreasonably
withheld or delayed), and such Holders shall be responsible for
all underwriting commissions and discounts in connection
therewith.

     
No person may participate in any underwritten registration
hereunder unless such person (i) agrees to sell such
person’s Transfer Restricted Notes on the basis reasonably
provided in any underwriting arrangements approved by the
persons entitled hereunder to approve such arrangements and
(ii) completes and executes all questionnaires, powers of
attorney, indemnities, underwriting agreements and other
documents reasonably required under the terms of such
underwriting arrangements.

     
9. Miscellaneous. (a) Amendments and
Waivers. The provisions of this Agreement may not be
amended, modified or supplemented, and waivers or consents to
departures from the provisions hereof may not be given, unless
the Company has obtained the written consent of Holders of a
majority in aggregate principal amount of the Notes, the
Exchange Notes and the Private Exchange Notes, taken as a single
class. Notwithstanding the foregoing, a waiver or consent to
depart from the provisions hereof with respect to a matter that
relates exclusively to the rights of Holders whose Notes,
Exchange Notes or Private Exchange Notes are being sold pursuant
to a Registration Statement and that does not directly or
indirectly affect the rights of other Holders may be given by
Holders of a majority in aggregate principal amount of the
Notes, the Exchange Notes and the Private Exchange Notes being
sold by such Holders pursuant to such Registration Statement.

     
(b) Notices. All notices and other communications
provided for or permitted hereunder shall be made in writing by
hand-delivery, first-class mail, telecopier or air courier
guaranteeing next-day delivery:

		
	 	     
    (i) if to a Holder, at the most current address given by
    such Holder to the Company in accordance with the provisions of
    this Section 9(b), which address initially is, with respect
    to each Holder, the address of such Holder maintained by the
    Registrar under the Indenture, with a copy in like manner to
    J.P. Morgan Securities Inc. and Citigroup Global Markets.
	 
	 	     
    (ii) if to an Initial Purchaser, initially at its address
    set forth in the Purchase Agreement; and
	 
	 	     
    (iii) if to the Company, initially at the address of the
    Company set forth in the Purchase Agreement.

     
All such notices and communications shall be deemed to have been
duly given: when delivered by hand, if personally delivered; one
business day after being delivered to a next-day air courier;
five business days after being deposited in the mail; and when
receipt is acknowledged by the recipient’s telecopier
machine, if sent by telecopier.

     
(c) Successors And Assigns. This Agreement shall be
binding upon the Company and its successors and assigns.

11

 

     
(d) Counterparts. This Agreement may be executed in
any number of counterparts (which may be delivered in original
form or by telecopier) and by the parties hereto in separate
counterparts, each of which when so executed shall be deemed to
be an original and all of which taken together shall constitute
one and the same agreement.

     
(e) Definition of Terms. For purposes of this
Agreement, (a) the term “business day”
means any day on which the New York Stock Exchange, Inc. is open
for trading, (b) the term “subsidiary” has
the meaning set forth in Rule 405 under the Securities Act
and (c) except where otherwise expressly provided, the term
“affiliate” has the meaning set forth in
Rule 405 under the Securities Act.

     
(f) Headings. The headings in this Agreement are for
convenience of reference only and shall not limit or otherwise
affect the meaning hereof.

     
(g) Governing Law. This Agreement shall be governed
by and construed in accordance with the laws of the State of New
York.

     
(h) Remedies. In the event of a breach by the
Company or by any Holder of any of their obligations under this
Agreement, each Holder or the Company, as the case may be, in
addition to being entitled to exercise all rights granted by
law, including recovery of damages (other than the recovery of
damages for a breach by the Company of its obligations under
Sections 1 or 2 hereof for which liquidated damages have
been paid pursuant to Section 3 hereof), will be entitled
to specific performance of its rights under this Agreement. The
Company and each Holder agree that monetary damages would not be
adequate compensation for any loss incurred by reason of a
breach by it of any of the provisions of this Agreement and
hereby further agree that, in the event of any action for
specific performance in respect of such breach, it shall waive
the defense that a remedy at law would be adequate.

     
(i) No Inconsistent Agreements. The Company
represents, warrants and agrees that (i) it has not entered
into, shall not, on or after the date of this Agreement, enter
into any agreement that is inconsistent with the rights granted
to the Holders in this Agreement or otherwise conflicts with the
provisions hereof, (ii) it has not previously entered into
any agreement which remains in effect granting any registration
rights with respect to any of its debt securities to any person
and (iii) without limiting the generality of the foregoing,
without the written consent of the Holders of a majority in
aggregate principal amount of the then outstanding Transfer
Restricted Notes, it shall not grant to any person the right to
request the Company to register any debt securities of the
Company under the Securities Act unless the rights so granted
are not in conflict or inconsistent with the provisions of this
Agreement.

     
(j) No Piggyback on Registrations. Neither the
Company nor any of its security holders (other than the Holders
of Transfer Restricted Notes in such capacity) shall have the
right to include any securities of the Company in any Shelf
Registration or Registered Exchange Offer other than Transfer
Restricted Notes.

     
(k) Severability. The remedies provided herein are
cumulative and not exclusive of any remedies provided by law. If
any term, provision, covenant or restriction of this Agreement
is held by a court of competent jurisdiction to be invalid,
illegal, void or unenforceable, the remainder of the terms,
provisions, covenants and restrictions set forth herein shall
remain in full force and effect and shall in no way be affected,
impaired or invalidated, and the parties hereto shall use their
reasonable best efforts to find and employ an alternative means
to achieve the same or substantially the same result as that
contemplated by such term, provision, covenant or restriction.
It is hereby stipulated and declared to be the intention of the
parties that they would have executed the remaining terms,
provisions, covenants and restrictions without including any of
such that may be hereafter declared invalid, illegal, void or
unenforceable.

     
(l) Notes Held by the Company, etc. Whenever
the consent or approval of Holders of a specified percentage of
principal amount of the Notes, Exchange Notes or Private
Exchange Notes is required hereunder, Notes, Exchange Notes or
Private Exchange Notes, as applicable, held by the Company or
its affiliates (other than subsequent Holders of Notes, Exchange
Notes or Private Exchange Notes if such subsequent Holders are
deemed to be affiliates solely by reason of their holdings of
such Notes, Exchange

12

 

Notes or Private Exchange Notes) shall not be counted in
determining whether such consent or approval was given by the
Holders of such required percentage.

     
Please confirm that the foregoing correctly sets forth the
agreement among the Company and the Initial Purchasers.

		
	 	
    Very truly yours,
	 
	 	
    WYETH

			
	 	By: 	
    /s/ Jack M. O’Connor

		
	 	
     

	 	
    Name: Jack M. O’Connor

			
	 	Title:	
    Vice President and Treasurer

Accepted: November 14, 2005

Acting severally on behalf of themselves

and the several Initial Purchasers

listed in Schedule I hereto.

		
	
    J.P. MORGAN SECURITIES INC.	 

			
	By: 	
    /s/ Maria Sramek	 

		
	
     
	 
	
    Name: Maria Sramek
    	 

			
	Title:	
    Vice President	 

		
	
    CITIGROUP GLOBAL MARKETS INC.	 

			
	By: 	
    /s/ Gerard L. Eastman Jr.	 

		
	
     
	 
	
    Name: Gerard L. Eastman Jr.
    	 

			
	Title:	
    Managing Director	 

13

 

ANNEX A

     
Each broker-dealer that receives Exchange Notes for its own
account pursuant to the Registered Exchange Offer must
acknowledge that it will deliver a prospectus in connection with
any resale of such Exchange Notes. The Letter of Transmittal
states that by so acknowledging and by delivering a prospectus,
a broker-dealer will not be deemed to admit that it is an
“underwriter” within the meaning of the Securities
Act. This Prospectus, as it may be amended or supplemented from
time to time, may be used by a broker-dealer in connection with
resales of Exchange Notes received in exchange for Notes where
such Notes were acquired by such broker-dealer as a result of
market-making activities or other trading activities. The
Company has agreed that, for a period of 180 days after the
Expiration Date (as defined herein), it will make this
Prospectus available to any broker-dealer for use in connection
with any such resale. See “Plan of Distribution”.

 

ANNEX B

     
Each broker-dealer that receives Exchange Notes for its own
account in exchange for Notes, where such Notes were acquired by
such broker-dealer as a result of market-making activities or
other trading activities, must acknowledge that it will deliver
a prospectus in connection with any resale of such Exchange
Notes. See “Plan of Distribution”.

 

ANNEX C

PLAN OF DISTRIBUTION

     
Each broker-dealer that receives Exchange Notes for its own
account pursuant to the Registered Exchange Offer must
acknowledge that it will deliver a prospectus in connection with
any resale of such Exchange Notes. This Prospectus, as it may be
amended or supplemented from time to time, may be used by a
broker-dealer in connection with resales of Exchange Notes
received in exchange for Notes where such Notes were acquired as
a result of market-making activities or other trading
activities. The Company has agreed that, for a period of
180 days after the Expiration Date, it will make this
prospectus, as amended or supplemented, available to any
broker-dealer for use in connection with any such resale. In
addition,
until                     ,
all dealers effecting transactions in the Exchange Notes may be
required to deliver a prospectus.

     
The Company will not receive any proceeds from any sale of
Exchange Notes by broker-dealers. Exchange Notes received by
broker-dealers for their own account pursuant to the Registered
Exchange Offer may be sold from time to time in one or more
transactions in the over-the-counter market, in negotiated
transactions, through the writing of options on the Exchange
Notes or a combination of such methods of resale, at market
prices prevailing at the time of resale, at prices related to
such prevailing market prices or at negotiated prices. Any such
resale may be made directly to purchasers or to or through
brokers or dealers who may receive compensation in the form of
commissions or concessions from any such broker-dealer or the
purchasers of any such Exchange Notes. Any broker-dealer that
resells Exchange Notes that were received by it for its own
account pursuant to the Registered Exchange Offer and any broker
or dealer that participates in a distribution of such Exchange
Notes may be deemed to be an “underwriter” within the
meaning of the Securities Act and any profit on any such resale
of Exchange Notes and any commission or concessions received by
any such persons may be deemed to be underwriting compensation
under the Securities Act. The Letter of Transmittal states that,
by acknowledging that it will deliver and by delivering a
prospectus, a broker-dealer will not be deemed to admit that it
is an “underwriter” within the meaning of the
Securities Act.

     
For a period of 180 days after the Expiration Date the
Company will promptly send additional copies of this Prospectus
and any amendment or supplement to this Prospectus to any
broker-dealer that requests such documents in the Letter of
Transmittal. The Company has agreed to pay all expenses incident
to the Registered Exchange Offer (including the expenses of one
counsel for the Holders of the Notes) other than commissions or
concessions of any broker-dealers and will indemnify the Holders
of the Notes (including any broker-dealers) against certain
liabilities, including liabilities under the Securities Act.

			
	 	o 	
    CHECK HERE IF YOU ARE A BROKER-DEALER AND WISH TO RECEIVE
    10 ADDITIONAL COPIES OF THE PROSPECTUS AND 10 COPIES OF ANY
    AMENDMENTS OR SUPPLEMENTS THERETO.

Name: 

Address:

If the undersigned is not a broker-dealer, the undersigned
represents that it is not engaged in, and does not intend to
engage in, a distribution of Exchange Notes. If the undersigned
is a broker-dealer that will receive Exchange Notes for its own
account in exchange for Notes that were acquired as a result of
market-making activities or other trading activities, it
acknowledges that it will deliver a prospectus in connection
with any resale of such Exchange Notes; however, by so
acknowledging and by delivering a prospectus, the undersigned
will not be deemed to admit that it is an
“underwriter” within the meaning of the Securities Act.

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