Document:

EX-4.3

 Exhibit 4.3 

CHANGE OF CONTROL PLAN 
 The executive and
employee change of control plan (the “Plan”) has been adopted by our board of directors on September 4, 2014 and was subsequently amended on December 11, 2014. 

The Plan is effective as from September 4, 2014 with respect to the concerned executives and will be effective towards the concerned employees upon the
execution by each concerned employee of an amendment to his or her employment agreement to this effect. 
 Subsequently, on each of March 4, 2020 and
November 5, 2020, the coverage of the Plan was extended for the benefit of any members of the executive committee of Cellectis not already covered by the Plan as of such respective date. 

A free translation of the relevant excerpt of the minutes of our board of directors’ meeting held on December 11, 2014 is presented on the following
page. 
  
  

CELLECTIS 
 A French
société anonyme with a share capital of EUR 1,470,986.05 
 Registered office: 8, rue de la Croix Jarry – 75013
Paris - France 
 428 859 052 R.C.S. Paris 

Translated excerpt of the minutes of the board of directors 

held on December 11, 2014 

During its meeting held on December 11, 2014, the board of directors of Cellectis (the “Company”) has made the following decision: 

Modifications of the circumstances in which a severance package should be paid by the Company to managers upon a change of control 

The chairman reports that his attention has been drawn to the need to clarify the circumstances in which the severance package approved by the board of
directors held on September 4, 2014 should be paid to the managers of the group upon a change of control. 
 The chairman reminds the directors the
list of the relevant managers together with their respective compensation levels: 
  

																	
	First name	  	Last name	  	Position	  	 Annual

compensation

(gross)
	 	  	 Bonus (% of

annual

compensation)
	 	 	Comments	 
	 André
	  	Choulika	  	Chairman of the board
of directors and CEO	  	 	240,000	 	  	 	80	% 	 			
	 Mathieu
	  	Simon	  	EVP	  	 	245,000	 	  	 	40	% 	 	 	contractual	 
	 David
	  	Sourdive	  	EVP	  	 	180,000	 	  	 	40	% 	 			
	 Philippe
	  	Duchateau	  	CSO	  	 	120,000	 	  	 	40	% 	 			
	 Marie-Bleuenn
	  	Terrier	  	GC	  	 	85,000	 	  	 	14	% 	 	 	(non contractual 2013 bonus)	 
	 Philippe
	  	Valachs	  	CS	  	 	144,000	 	  	 	40	% 	 			
	 Thierry
	  	Moulin	  	CFO	  	 	140,000	 	  	 	40	% 	 			
	 Delphine
	  	Jay	  	HR	  	 	110,000	 	  	 	12	% 	 	 	(non contractual 2013 bonus 2013)	 
	 Julia
	  	Berretta	  	BusDev	  	 	70,000	 	  	 	12	% 	 	 	(non contractual 2013 bonus)	 
	 Laurent
	  	Poirot	  	Innovation Manager	  	 	70,000	 	  	 	17	% 	 	 	(non contractual 2013 bonus)	 
	 Julianne
	  	Smith	  	VP CART Platform	  	 	80,000	 	  	 	21	% 	 	 	(non contractual 2013 bonus)	 

 The chairman also reminds the directors that the board of directors has, during its meeting held on
September 4, 2014, set this severance package at an amount equal to 24 months of gross fixed salary (or for executives, 24 months of compensation) increased by an amount equal to the maximum target bonus to which the employees or executives
concerned may be entitled for the year of their departure, or, in the absence of such a target bonus, 1.5 times the last annual bonus paid to them by the Company during the 12 months prior to their departure. 

Notwithstanding the above, the board of directors, upon recommendation of the compensation committee, decides that the severance package to be paid to
André Choulika, chief executive officer of Cellectis SA, shall amount to two years of compensation and two years of maximal target bonus to take into account the fact that André Choulika is not entitled to any legal or conventional
severance payments in the absence of an employment agreement having been entered into between himself and the Company. 
 This amount would be in addition
to any legal and conventional severance payments owed by the Company to the employees or executives concerned. 
 The Chairman suggests: 

 

	 	•	 	 to extend the definition of a « change of control » triggering the payment of such a severance
package from the crossing of the threshold of 50% of the share capital or voting rights only to all circumstances qualifying as a change of control within the meaning of article L. 233-3 of the French
Commercial code; and 

  

	 	•	 	 with respect to managers having entered into an employment agreement with the Company, to clarify that their
departure as a result of a significant reduction of their responsabilities would trigger the payment of the abovementioned severance package only to the extent that such departure occurs within the 12-month
period following a change of control; and 

  

	 	•	 	 to extend from 12 to 36 months following a change of control the period during which the concerned managers would
benefit from this severance package. 

 This amount would thus be paid by the Company should any of the following events occur, it being
provided that such triggering events replace and supersede the triggering events approved by the board of directors during its meeting held on September 4, 2014: 
  

	 	•	 	 with respect to all managers, whether they are executives of the Company or have entered into an employment
agreement with the Company: should the employees or executives concerned not be renewed or be dismissed other than for gross misconduct (faute lourde) within the meaning of French labor law within the
36-month period following a change of control of the Company within the meaning of article L. 233-3 of the French Commercial code. 

	 	•	 	 with respect to executives only: should they resign within the abovementioned 36-month period as a result of a significant reduction of their duties or compensation. 

 The president
indicates that the granting to David Sourdives, deputy chief executive officer, and to himself of the severance package qualifies as a related party agreement which is therefore subject to the prior approval of the board of directors. 

The board of directors, after discussions, unanimously: 
  

	 	•	 	 approves to put into place the abovementioned amendments relating to the circumstances in which a
severance package shall be paid to managers of the Company upon a change of control, it being specified that André Choulika et David Sourdives, did not participate to the vote, 

* * * 
 Translated
excerpt of the minutes of the board of directors 
 held on March 4, 2020 

During its meeting held on March 4, 2020, the board of directors of the Company has made the following decision: 

“The chairman reminds the directors that the board of directors has, during its meeting held on September 4, 2014, approved the implementation of a
severance package to the benefit of certain managers upon a change of control of the Company. In order to ensure the retention of the members of the executive committee, the chairman, upon recommendation of the compensation committee, proposes to
the board that the benefit of this severance package be extended to the members of the current executive committee who do not benefit from it. 
 The board
of directors, after discussions, unanimously: 
  

	 	•	 	 considering that providing comfort to the group’s main executives as to their situation in the event of a
change of control of the Company, and thereby ensuring their continued presence within the group, is fully in line with the Company’s interests, approves the implementation of a severance package, upon a change of control of the Company, for
the benefit of members of the company’s executive committee who do not already enjoy one, which shall not be more favorable than the package approved in 2014” 

* * * 
 Translated
excerpt of the minutes of the board of directors 
 held on November 5, 2020 

During its meeting held on November 5, 2020, the board of directors of the Company has made the following decision: 

“The chairman reminds the directors that the board of directors has, during its meeting held on March 4, 2020, approved the implementation of a
severance package to the benefit of members of the company’s executive committee who do not already enjoy one. The chairman, proposes to the board that this severance package benefits to new employees having joined the current executive
committee since March 4, 2020. 
 The board of directors, after discussions, unanimously: 

 

	 	•	 	 considering that providing comfort to the group’s main executives as to their situation in the event of a
change of control of the Company, and thereby ensuring their continued presence within the group, is fully in line with the Company’s interests, approves the implementation of a severance package, upon a change of control of the Company, for
the benefit of members of the company’s executive committee who do not already enjoy one, which shall not be more favorable than the package approved in 2014” 

* * 
 *EX-10.1

 Exhibit 10.1 

FIFTH AMENDMENT TO 

THIRD AMENDED AND RESTATED LOAN AND SECURITY AGREEMENT 

THIS FIFTH AMENDMENT TO THIRD AMENDED AND RESTATED LOAN AND SECURITY AGREEMENT (this “Amendment”) is entered into as of
March 2, 2022 (the “Effective Date”), by and among WELLS FARGO CAPITAL FINANCE, LLC, a Delaware limited liability company, as the arranger and administrative agent (“Agent”) for the Lenders (as defined in the
Credit Agreement referred to below), the Lenders party hereto, LSB INDUSTRIES, INC., a Delaware corporation (“Parent”), certain Subsidiaries of Parent designated on the signature pages hereto as borrowers (together with Parent, such
Subsidiaries are collectively referred as the “Borrowers”) and certain Subsidiaries of Parent designated on the signature pages hereto as guarantors (such Subsidiaries are collectively referred to as the
“Guarantors” and together with the Borrowers, such Guarantors are collectively referred to as the “Loan Parties”). 

WHEREAS, the Borrowers, Agent, and the Lenders are parties to that certain Third Amended and Restated Loan and Security Agreement dated as of
January 17, 2017 (as amended, restated, modified or supplemented from time to time, the “Credit Agreement”); and 

WHEREAS, the Borrowers have requested that the Lenders agree to amend the Credit Agreement in certain respects as set forth herein, and the
Lenders have agreed to the foregoing, on the terms and conditions set forth herein; 
 WHEREAS, the Borrowers have requested that the
Lenders agree to amend the Credit Agreement in certain respects as set forth herein, and the Lenders have agreed to the foregoing, on the terms and conditions set forth herein. 

NOW THEREFORE, in consideration of the premises and mutual agreements herein contained, the parties hereto agree as follows: 

1. Defined Terms. Unless otherwise defined herein, capitalized terms used herein and not otherwise defined shall have the meanings
ascribed to such terms in the Credit Agreement. 
 2. Amendment to Credit Agreement. In reliance upon the representations and
warranties of the Borrowers set forth in Section 6 below, and subject to the satisfaction of the conditions set forth in Section 5 below, the Credit Agreement is hereby amended, which amendment
shall first take effect of the date the conditions set forth in Section 5 below are satisfied, as follows: 
 (a)
The definition of the term ““LSB Notes” set forth in Section 1.1 of the Credit Agreement is hereby amended and restated in its entirety as follows: 

“LSB Notes” means the general senior secured notes of Parent maturing not earlier than 2026 in the aggregate
principal amount not to exceed $800,000,000. 

 3. Continuing Effect. Except as expressly set forth in
Section 2 of this Amendment, nothing in this Amendment shall constitute a modification or alteration of the terms, conditions or covenants of the Credit Agreement or any other Loan Document, or a waiver of any other terms
or provisions thereof, and the Credit Agreement and the other Loan Documents shall remain unchanged and shall continue in full force and effect, in each case as amended hereby. 

4. Reaffirmation and Confirmation. Each Loan Party hereby ratifies, affirms, acknowledges and agrees that the Credit Agreement and the
other Loan Documents to which it is a party represent the valid, enforceable and collectible obligations of such Loan Party, and further acknowledges that there are no existing claims, defenses, personal or otherwise, or rights of setoff whatsoever
with respect to the Credit Agreement or any other Loan Document. Each Loan Party hereby agrees that this Amendment in no way acts as a release or relinquishment of the Liens and rights securing payments of the Obligations. The Liens and rights
securing payment of the Obligations are hereby ratified and confirmed by each Loan Party in all respects. 
 5. Conditions to
Effectiveness. This Amendment shall become effective, and the amendment to the Credit Agreement set forth in Section 2 above shall, in each case, become operative, as of the date hereof upon Agent’s receipt of a
copy of this Amendment executed and delivered by Agent, the Lenders and the Loan Parties. 
 6. Representations and Warranties. In
order to induce Agent and the Lenders to enter into this Amendment, each Loan Party hereby represents and warrants to Agent and the Lenders that: 

(a) after giving effect to this Amendment, all representations and warranties contained in the Loan Documents to which such Loan Party is a
party are true, correct and complete in all material respects (except that such materiality qualifier shall not be applicable to any representations and warranties that already are qualified or modified by materiality in the text thereof) on and as
of the date of this Amendment, as though made on and as of such date (except to the extent that such representations and warranties relate solely to an earlier date, in which case such representations and warranties shall be true, correct and
complete in all material respects (except that such materiality qualifier shall not be applicable to any representations and warranties that already are qualified or modified by materiality in the text thereof) on and as of such earlier date); 

(b) no Default or Event of Default has occurred and is continuing or will exist after this Amendment becomes effective; and 

(c) this Amendment and the Loan Documents, as amended hereby, constitute legal, valid and binding obligations of such Loan Party and are
enforceable against such Loan Party in accordance with their respective terms, except as enforcement may be limited by equitable principles or by bankruptcy, insolvency, reorganization, moratorium or similar laws relating to or limiting
creditors’ rights generally. 
 7. Miscellaneous. 

(a) Expenses. The Borrowers jointly and severally agree to pay, promptly after demand therefor is made by Agent, all reasonable and
documented out-of-pocket costs and expenses of Agent (including reasonable attorneys’ fees of a single firm of counsel to Agent) incurred in connection with the
preparation, negotiation, execution, delivery and administration of this Amendment and all other instruments or documents provided for herein or delivered or to be delivered hereunder or in connection herewith. All obligations provided herein shall
survive any termination of this Amendment and the Credit Agreement as amended hereby. 

  
 -2- 

 (b) Choice of Law and Venue; Jury Trial Waiver; Reference Provision. Without limiting
the applicability of any other provision of the Credit Agreement or any other Loan Document, the terms and provisions set forth in Section 13 of the Credit Agreement are expressly incorporated herein by reference. 

(c) Counterparts; Electronic Execution. This Amendment may be executed in any number of counterparts and by different parties on
separate counterparts, each of which, when executed and delivered, shall be deemed to be an original, and all of which, when taken together, shall constitute but one and the same Amendment. Execution of any such counterpart may be by means of
(a) an electronic signature that complies with the federal Electronic Signatures in Global and National Commerce Act, as in effect from time to time, state enactments of the Uniform Electronic Transactions Act, as in effect from time to time,
or any other relevant and applicable electronic signatures law; (b) an original manual signature; or (c) a faxed, scanned, or photocopied manual signature. Each electronic signature or faxed, scanned, or photocopied manual signature shall
for all purposes have the same validity, legal effect, and admissibility in evidence as an original manual signature. Agent reserves the right, in its discretion, to accept, deny, or condition acceptance of any electronic signature on this
Amendment. Any party delivering an executed counterpart of this Amendment by faxed, scanned or photocopied manual signature shall also deliver an original manually executed counterpart, but the failure to deliver an original manually executed
counterpart shall not affect the validity, enforceability and binding effect of this Amendment. 
 [Signature Page Follows] 

  
 -3- 

 IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be executed by their
respective officers thereunto duly authorized and delivered as of the date first above written. 
  

			
	BORROWERS:
	
	 LSB INDUSTRIES, INC. 

CHEMEX I CORP. 
 CHEROKEE NITROGEN LLC

EDC AG PRODUCTS COMPANY L.L.C. 
 EL DORADO AMMONIA
L.L.C.
 EL DORADO CHEMICAL COMPANY
 EL DORADO
NITROGEN, L.L.C. 
 LSB CHEMICAL L.L.C. 
 PRYOR
CHEMICAL COMPANY
 TRISON CONSTRUCTION, INC.

		
	By:	 	/s/ Kristy Carver
	Name:	 	Kristy Carver
	Title:	 	Senior Vice President, Treasurer
		 	and Assistant Secretary

  
 Signature Page to Fifth
Amendment to Third Amended and Restated Loan and Security Agreement 

 
			
	AGENT AND LENDERS: 

	
	WELLS FARGO CAPITAL FINANCE, LLC, as Agent 

		
	By:	 	/s/ Becky Rountree
	Name:	 	Becky Rountree
	Title:	 	Vice President
	
	WELLS FARGO BANK, NATIONAL ASSOCIATION, as a Lender
		
	By:	 	/s/ Becky Rountree
	Name:	 	Becky Rountree
	Title:	 	Vice President

  

  
 Signature Page to Fifth
Amendment to Third Amended and Restated Loan and Security Agreement

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