Document:

Amended & Restated License Agreement

 Exhibit 10.10 
  
 AMENDED & RESTATED LICENSE AGREEMENT 
  
 Effective as of October 13, 2003 (“Effective Date”), THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, a body having
corporate powers under the laws of the State of California (“STANFORD”), and Google Inc., a Delaware corporation having a principal place of business at 2400 Bayshore Parkway, Mountain View, CA 94043 (“GOOGLE”), agree as follows:

  
 1. BACKGROUND 
  
 1.1 STANFORD and Google Inc., a California corporation and predecessor in
interest to GOOGLE, are parties to a License Agreement effective December 1, 1998 (“Original Agreement”) and an Amendment effective May 1, 2000 (“Amendment”). It is the intention of the parties that this Agreement will amend and
restate the Original Agreement and Amendment in its entirety. 
  
 1.2 STANFORD has an assignment of “Improved text searching in hypertext systems” developed by Lawrence Page (“Invention[s]”), as described in Stanford Docket S96-213, and any Licensed Patent(s), as hereinafter defined,
which may issue to such Invention(s). 
  
 1.3 STANFORD has
certain non-patented Technology, as defined in Paragraph 2.2 below, which STANFORD wishes to make available nonexclusively.  
  
 1.4 STANFORD desires to have the Technology, Software, and Invention(s) perfected and marketed at the earliest possible time in order that products
resulting therefrom may be available for public use and benefit. 
  
 1.5 GOOGLE desires a license under said Technology, Software, Invention(s), and Licensed Patent(s) to develop, manufacture, use, market, and sell Licensed Product(s) and Licensed Program(s) in the field of use of internet search
applications. 
  
 1.6 The Technology, Software, and Invention(s)
were made in the course of research supported in part by the U.S. Government. 
  
 1.7 GOOGLE exercised its Option in the Original Agreement. STANFORD and GOOGLE are parties to a separate license agreement effective July 1, 2001 for “Information Extraction from a Database” (Stanford
Docket S01-028) and “Background Surfing” (Stanford Docket S01-027).  

 2. DEFINITIONS 
  
 2.1 “Licensed Patent(s)” means 

	 	(a)	STANFORD’s U.S. Patent 6,285,999 filed January 9, 1998 and issued September 4, 2001, 

	 	(b)	any Letters Patent issued upon STANFORD’s U.S. patent application Serial Number 09/895,174 filed July 2, 2001,  

	 	(c)	any Letters Patent issued upon STANFORD’s U.S. patent application Serial Number 09/899,068 filed July 6, 2001,  

  
 any foreign patents corresponding thereto, and/or any
divisions, continuations, or reissue thereof. 
  
 2.2
“Technology” means existing non-patented and non-copyrighted ideas, technical data and information generally described in Appendix A. Technology excludes Software. 
  
 2.3 “Software” means the Google source code, including any other material relating to Google source code which
will be provided to GOOGLE pursuant to this Agreement. 
  
 2.4
“Licensed Product(s)” means any product or part thereof in the Licensed Field of Use, the manufacture, use, or sale of which: 
  

	 	a)	Is covered by a valid claim of an issued, unexpired Licensed Patent(s) directed to the Invention(s). A claim of an issued, unexpired Licensed Patent(s) shall be presumed to be valid
unless and until it has been held to be invalid by a final judgment of a court of competent jurisdiction from which no appeal can be or is taken; or 

	 	(b)	Is covered by any claim being prosecuted in a pending application directed to the Invention(s). 

  
 2.5 “Licensed Program(s)” means those computer programs developed by GOOGLE in the Licensed Field of Use,
including manuals and related documentation, which include a material portion of, or which are derived from, Software. 
  
 2.6 “Licensed Field of Use” means internet search applications. 
  
 2.7 “Use Sublicense(s)” means any agreement or arrangement between GOOGLE and any customer for the use of Licensed
Program(s). 
  
 2.8 “Exclusive” means that, subject to
Article 5, STANFORD shall not grant further licenses in the Licensed Field of Use. 
  
 2.9 “Patent Sublicense” means any sublicense of a Licensed Patent granted by GOOGLE to a third party to allow that third party to make, have made, use, sell, offer for sale, and import its own Licensed
Products without GOOGLE providing products or services. 
  
 2.10
“Stanford Indemnitees” means STANFORD and Stanford Hospitals and Clinics, and their respective trustees, officers, employees, students, and agents. 
  

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 3. GRANT 
  
 3.1 STANFORD hereby grants and GOOGLE hereby accepts a worldwide license in the Licensed Field of Use to make, have made, use, sell, offer for sale, and
import Licensed Product(s). 
  
 3.2 The above license in
Paragraph 3.1 is Exclusive for each Licensed Patent, including the right to grant Patent Sublicenses under Article 14, in the Licensed Field of Use for a term commencing as of December 1, 1998 and ending on 10 years from its issuance date.
Thereafter, said license shall be nonexclusive until its expiration date. For example, the Exclusive period for U.S. Patent 6,285,999 expires on September 4, 2011. 
  
 3.3 STANFORD grants, and GOOGLE accepts 
  

	 	(a)	A worldwide license to use, copy, modify, enhance, make derivative works, and distribute Software as part of the development of Licensed Program(s); 

	 	(b)	A worldwide license to grant Use Sublicense(s) to Software as part of Licensed Program(s) solely in the Licensed Field of Use and to grant such sublicenses through multiple tiers of
sublicenses; 

	 	(c)	A worldwide license to allow others to use the Licensed Program(s) for internet searching. 

  
 3.4 The above licenses in Paragraph 3.3 are Exclusive in the Licensed Field of Use for a term commencing as of December 1,
1998 and ending on September 4, 2011. Thereafter, said license shall be nonexclusive until expiration of the Software’s copyright. 
  
 3.5 GOOGLE agrees: 
  

	 	(a)	To maintain the quality of Software; 

	 	(b)	To affix an appropriate notice of copyright to all copyrightable materials licensed under Paragraph 3.3 hereof, and to do such things as are reasonable to protect and preserve
STANFORD’s rights in such copyrights; 

	 	(c)	To exercise due care in protecting Software from disclosure to third parties, at least to the degree it exercises care in protecting its own proprietary information; and

	 	(d)	To take appropriate action with its employees, consultants, and sublicensee(s) to satisfy its obligation under this Agreement with respect to maintaining the above degree of
protection for Software. 

  
 However, GOOGLE shall
have no confidentiality obligations with respect to any information if the same or similar information is or becomes within the public domain through no act of GOOGLE in breach of this Agreement, is independently developed by GOOGLE, or is received
unrestricted from another source who was not under an obligation of confidentiality to STANFORD. 
  
 3.6 GOOGLE agrees that the source code embodied in the Software is for internal use only and that when sublicensing only object code in binary form will
be distributed, except as provided under reasonable source code escrow arrangements. 
  

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 3.7 STANFORD hereby grants and GOOGLE hereby accepts a worldwide, nonexclusive license to use, enhance
and modify the Technology to develop, make, have made, use, market, sell, and otherwise distribute any products and/or services in the Licensed Field of Use. 
  
 3.8 The above license in Paragraph 3.7 shall remain in effect unless terminated in accordance with Article 16 hereof. STANFORD retains all rights in
tangible and intangible property provided to GOOGLE. 
  
 3.9
STANFORD shall have the right to practice the Invention(s) and use the Technology and Software for its own bona fide uses, including sponsored research and collaborations. STANFORD shall have the right to publish any information included in
Technology, Software, and Licensed Patent(s). 
  
 4. PATENT PROSECUTION

  
 4.1 The filing, prosecution, and maintenance of all
Licensed Patent(s) shall be the primary responsibility of GOOGLE; provided, however, STANFORD will have final approval before proceeding with any substantive actions, including pre-approve or pre-disapprove the abandonment of any Licensed Patent or
claims. GOOGLE’s patent counsel will concurrently provide STANFORD and GOOGLE with copies of all material correspondence related to said prosecution. GOOGLE’s patent counsel will use its best efforts to incorporate STANFORD’s
reasonable suggestions regarding the prosecution. GOOGLE is responsible for the payment of all charges and fees by GOOGLE’s patent counsel related to the filing, prosecution, and maintenance of the Licensed Patents. In the event that a conflict
arises with respect to the Licensed Patents, GOOGLE and STANFORD agree to meet and discuss, but STANFORD will still have final approval. 
  
 4.2 GOOGLE may request that patent applications corresponding to the Invention(s) be filed in foreign countries in addition to those selected by STANFORD.
Should GOOGLE elect to abandon any patent or patent application in any country, it shall give timely notice to STANFORD, who may continue prosecution or maintenance, at its sole expense and GOOGLE shall have no further rights with respect to such
patent application or patent in such country. 
  
 5. GOVERNMENT RIGHTS

  
 5.1 This Agreement is subject to all of the terms and
conditions of Title 35 United States Code Sections 200 through 204, including an obligation that Licensed Product(s) sold or produced in the United States be “manufactured substantially in the United States,” and GOOGLE agrees to take all
reasonable action necessary on its part as licensee to enable STANFORD to satisfy its obligation thereunder, relating to Invention(s). 
  

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 5.2 STANFORD may distribute all of Software, for such use or further distribution as may be reserved,
required, or permitted by said U.S. Government grants or any applicable law or regulation or contractual obligation of STANFORD relating thereto, and GOOGLE agrees to take all action necessary on its part as licensee of STANFORD to enable STANFORD
to comply with such obligations. GOOGLE is not otherwise required by this Agreement to provide any services related to such distribution. 
  
 6. ENHANCEMENTS BY GOOGLE 
  
 GOOGLE shall own all right, title and interest in any enhancements made by GOOGLE and all intellectual property rights related thereto. During the period of this
Agreement, subject to mutually agreeable terms, STANFORD may obtain from GOOGLE, any enhancements made by GOOGLE to Software. STANFORD agrees not to further distribute such enhancements without the prior written consent of GOOGLE. 
  
 7. DILIGENCE 
  
 7.1 As an inducement to STANFORD to enter into this Agreement, GOOGLE agrees to use all reasonable efforts and diligence to
proceed with the development, manufacture, and sale or lease of Licensed Product(s) and to diligently develop markets for the Licensed Product(s). STANFORD may convert the licenses in Paragraphs 3.1 and 3.3 to nonexclusive if GOOGLE does not meet
the following conditions: 
  

	 	(A)	number of unique visitors to GOOGLE per year is greater than 50,000,000; and  

	 	(B)	number of searches performed by GOOGLE per year is greater than 25,000,000,000.  

  
 7.2 GOOGLE also agrees to use all reasonable efforts and diligence to proceed with the development, manufacture, and
sublicensing of Licensed Program(s) and to diligently develop markets for the Licensed Program(s). 
  
 7.3 Progress Report—On or before August 1 of each year, GOOGLE shall make a written annual report to STANFORD covering the preceding year
ending June 30, regarding the progress of GOOGLE toward commercial use of Licensed Product(s). Such report shall include, as a minimum, information sufficient to enable STANFORD to satisfy reporting requirements of the U.S. Government and for
STANFORD to ascertain progress by GOOGLE toward meeting the diligence requirements of this Article 7. 
  

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 8. ROYALTIES 
  
 8.1 Pursuant to the Original Agreement, GOOGLE agreed to pay to STANFORD a noncreditable, nonrefundable license issue royalty of [***] upon signing
the Original Agreement. In addition, GOOGLE agreed to issue to STANFORD shares of GOOGLE stock equivalent to [***] equity of issued shares after the round of investor financing which resulted in a Eight Million Dollars ($8,000,000) post-money
valuation. On April 14, 1999, GOOGLE issued [***] shares (as adjusted for stock splits effected August 1999, February 2003, and June 2003) of Series A Preferred Stock to STANFORD. On April 17, 2000, STANFORD transferred [***] of all
shares granted to STANFORD to the inventors: Lawrence Page [***] shares and Sergey Brin [***] shares, with STANFORD retaining [***] shares (in each case as adjusted for stock splits). STANFORD acknowledges the receipt of the
[***] license issue royalty and the issuance of the aforementioned shares of Series A Preferred Stock in satisfaction of GOOGLE’s obligations under this Paragraph 8.1. 
  
 8.2 Beginning December 1, 1999 and each December 1 thereafter, GOOGLE also shall pay to STANFORD a yearly advance royalty as
set forth below. Said yearly royalty payments are nonrefundable and noncreditable. 
  

			
	 Payment due December 1
	  	Yearly advance royalty
	 1999 – 2002
	  	$[***]
	 2003 – 2005
	  	$[***]
	 2006 – 2010
	  	$[***]
	 2011 – end of last Licensed Patent’s Exclusive period
	  	$[***]
	 End of last Licensed Patent’s Exclusive period – expiration of Software’s copyright
	  	$[***]

  
 8.3 Royalty
payments to STANFORD shall be in U.S. Dollars. All non-U.S. taxes related to royalty payments shall be paid by GOOGLE and are not deductible from the payments due STANFORD. 
  
 9. NEGATION OF WARRANTIES 
  
 9.1 Nothing in this Agreement is or shall be construed as: 
  

	 	(a)	A warranty or representation by STANFORD as to the validity or scope of any Licensed Patent(s); 

	 	(b)	A warranty or representation that anything made, used, sold, or otherwise disposed of under any license granted in this Agreement is or will be free from infringement of patents,
copyrights, and other rights of third parties; 

	 	(c)	An obligation to bring or prosecute actions or suits against third parties for infringement, except to the extent and in the circumstances described in Article 13;

  

 -6- 

	 	(d)	Granting by implication, estoppel, or otherwise any licenses or rights under patents or other rights of STANFORD or other persons other than Licensed Patent(s), regardless of
whether such patents or other rights are dominant or subordinate to any Licensed Patent(s); or 

	 	(e)	An obligation to furnish any technology or technological information other than the Technology. 

  
 9.2 Except as expressly set forth in this Agreement, STANFORD MAKES NO REPRESENTATIONS AND EXTENDS NO WARRANTIES OF ANY
KIND, EITHER EXPRESS OR IMPLIED. THERE ARE NO EXPRESS OR IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, OR THAT THE USE OF THE Licensed Product(s), Licensed Program(s), Software, OR Technology WILL NOT INFRINGE ANY
PATENT, COPYRIGHT, TRADEMARK, OR OTHER RIGHTS OR ANY OTHER EXPRESS OR IMPLIED WARRANTIES. 
  
 10. INDEMNITY 
  
 10.1 GOOGLE agrees to indemnify, hold harmless, and defend all Stanford Indemnitees against any and all claims for death, illness, personal injury, property damage, and improper business practices arising out of the manufacture, use,
sale, or other disposition of Invention(s), Licensed Patent(s), Licensed Product(s), Licensed Program(s), Software, or Technology by GOOGLE or sublicensee(s), or their customers.  
  
 10.2 STANFORD shall not be liable for any indirect, special, consequential or other damages whatsoever, whether
grounded in tort (including negligence), strict liability, contract or otherwise. STANFORD shall not have any responsibilities or liabilities whatsoever with respect to Licensed Patent(s), Licensed Product(s), Licensed Program(s), Software, or
Technology.  
  
 10.3 GOOGLE shall at all times comply,
through insurance or self-insurance, with all statutory workers’ compensation and employers’ liability requirements covering any and all employees with respect to activities performed under this Agreement. 
  
 10.4 In addition to the foregoing, GOOGLE shall maintain, during the term of
this Agreement, Comprehensive General Liability Insurance, including Products Liability Insurance, with reputable and financially secure insurance carrier(s) to cover the activities of GOOGLE and its sublicensee(s). Such insurance shall
provide minimum limits of liability of $1 Million and shall include all Stanford Indemnitees as additional insureds. Such insurance shall be written to cover claims incurred, discovered, manifested, or made during or after the expiration of
this Agreement and should be placed with carriers with ratings of at least A- as rated by A.M. Best. Within 15 days of the Effective Date of this Agreement, GOOGLE shall furnish a Certificate of Insurance evidencing primary coverage and
additional insured requirements and requiring thirty (30) days prior written notice of cancellation or material change to STANFORD. GOOGLE shall advise STANFORD, in writing, that it maintains excess liability coverage (following form) over
primary insurance for at least the minimum limits set forth above. All such insurance of GOOGLE shall be primary coverage; insurance of STANFORD and Stanford Hospitals and Clinics shall be excess and noncontributory.  
  

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 11. MARKING 
  
 Prior to the issuance of patents on the Invention(s), GOOGLE agrees to mark Licensed Product(s) (or their containers or labels) made, sold, or otherwise disposed of by it
under the license granted in this Agreement with the words “Patent Pending,” and following the issuance of one or more patents, with the numbers of the Licensed Patent(s). 
  
 12. NAMES AND MARKS 
  
 12.1 GOOGLE agrees not to identify STANFORD in any promotional advertising or other promotional materials to be disseminated to the public or any portion
thereof or to use the name of any STANFORD faculty member, employee, or student or any trademark, service mark, trade name, or symbol of STANFORD or Stanford Hospitals and Clinics, or that is associated with any of them, without STANFORD’s
prior written consent; provided, however, that GOOGLE may disclose that Messrs. Brin and Page conceived the Invention and the Technology while students at STANFORD. 
  
 12.2 STANFORD hereby disclaims any ownership interest in the Google logo, name, and mark, and the “I’m Feeling
Lucky” name and mark. 
  
 13. INFRINGEMENT BY OTHERS: PROTECTION OF
PATENTS 
  
 13.1 Infringement Procedure. GOOGLE
will promptly notify STANFORD if it believes a third party infringes a Licensed Patent. During the Licensed Patent’s Exclusive period of this Agreement only, GOOGLE may have the right to institute a suit against this third party as provided in
Sections 13.1 –13.6. 
  
 13.2 Stanford Suit. STANFORD
has the first right to institute suit, and may name GOOGLE as a party for standing purposes. If STANFORD decides to institute suit, it will notify GOOGLE in writing. If GOOGLE does not notify STANFORD in writing that it desires to jointly
prosecute the suit within 15 days after the date of the notice, GOOGLE will assign and hereby does assign to STANFORD all rights, causes of action, and damages resulting from the alleged infringement. STANFORD will bear the entire cost of the
litigation and will retain the entire amount of any recovery or settlement.  
  
 13.3 Joint Suit. If STANFORD and GOOGLE so agree, they may institute suit jointly. If so, they will: 
  

	 	(A)	Prosecute the suit in both their names;  

	 	(B)	Bear the out-of-pocket costs equally;  

	 	(C)	Share any recovery or settlement equally; and  

	 	(D)	Agree how they will exercise control over the action.  

  

 -8- 

 13.4 Licensee Suit. If neither Section 13.2 nor 13.3 apply, GOOGLE may institute and prosecute a
suit so long as it conforms with the requirements of this Section. GOOGLE will diligently pursue the suit and GOOGLE will bear the entire cost of the litigation, including expenses and counsel fees incurred by STANFORD. GOOGLE will keep
STANFORD reasonably apprised of all developments in the suit, and will seek STANFORD’s input and approval on any substantive submissions or positions taken in the litigation regarding the scope, validity and enforceability of the Licensed
Patent. GOOGLE will not prosecute, settle or otherwise compromise any such suit in a manner that adversely affects STANFORD’s interests without STANFORD’s prior written consent. STANFORD may be named as a party only if  

 

	 	(A)	GOOGLE’s and STANFORD’s respective counsel recommend that such action is necessary in their reasonable opinion to achieve standing; 

	 	(B)	STANFORD is not the first named party in the action; and  

	 	(C)	the pleadings and any public statements about the action state that GOOGLE is pursuing the action and that GOOGLE has the right to join STANFORD as a party. 

  
 13.5 Recovery. If GOOGLE sues
under Section 13.4, then any recovery in excess of any unrecovered litigation costs and fees will be shared with STANFORD as mutually agreed upon prior to the initiation of litigation. GOOGLE and STANFORD will negotiate in good faith appropriate
compensation to STANFORD for any non-cash settlement or non-cash cross-license.  
  
 13.6 Abandonment of Suit. If either STANFORD or GOOGLE commences a suit and then wants to abandon the suit, it will give timely notice to the other party. The other party may continue prosecution of the suit
after STANFORD and GOOGLE agree on the sharing of expenses and any recovery in the suit. 
  
 14. PATENT SUBLICENSE(S) 
  
 14.1 Permitted Sublicensing. GOOGLE may grant Patent Sublicenses in the Licensed Field of Use only during the Licensed Patent’s Exclusive period and only if GOOGLE is developing or selling Licensed Products. 
  
 14.2 Required Sublicensing. If GOOGLE is unable or unwilling to serve
or develop a potential market or market territory for which there is a company willing to be a sublicensee, GOOGLE will, at STANFORD’s request, negotiate in good faith a Patent Sublicense with any such sublicensee.  
  
 14.3 Sublicense Requirements. Any Patent Sublicense: 
  

	 	(A)	is subject to this Agreement; 

	 	(B)	will reflect that any sublicensee will not further sublicense; 

	 	(C)	will expressly include the provisions of Articles 9 and 10 for the benefit of STANFORD; and 

	 	(D)	will require the transfer of all obligations, including the payment of royalties specified in the sublicense, to STANFORD or its designee, if this Agreement is terminated.

  

 -9- 

 14.4 Copy of Sublicenses. GOOGLE will submit to STANFORD a copy of any Patent Sublicense granted
pursuant to this Article 14. 
  
 14.5 Sharing of Sublicensing
Income. Prior to issuing any Patent Sublicense, GOOGLE agrees to negotiate with STANFORD to reach a mutually satisfactory agreement and reasonable sharing of Patent Sublicensing income payable to STANFORD for any such Patent Sublicense executed
during the Licensed Patent’s Exclusive period. 
  
 15. USE
SUBLICENSE(S) 
  
 15.1 Each Use Sublicense(s) shall
maintain that the Use Sublicensee(s)’s rights in Software and Licensed Program(s) shall not be transferable and shall not be sold, or further licensed. 
  
 15.2 Upon request by STANFORD, GOOGLE agrees to provide to STANFORD the general terms and conditions used in sublicensing the Licensed Program(s).

  
 15.3 It is understood that the Use Sublicense(s) entered into
by GOOGLE during the term of this Agreement may have a duration extending beyond the expiration of this Agreement. 
  
 15.4 After termination of this Agreement, for whatever reason, GOOGLE retains the right to use Software internally to service its existing sublicensee(s).

  
 16. TERMINATION 
  
 16.1 GOOGLE may terminate this Agreement by giving STANFORD notice in writing
at least thirty (30) days in advance of the effective date of termination selected by GOOGLE. 
  
 16.2 STANFORD may terminate this Agreement if GOOGLE: 
  

	 	(a)	Is in default in payment of royalty or providing of reports; 

	 	(b)	Is in breach of any provision hereof; or 

	 	(c)	Provides any false report; 

  
 and GOOGLE fails to remedy any such default, breach, or false report within thirty (30) days after written notice thereof by STANFORD. 
  
 16.3 Surviving any termination or expiration are: 
  

	 	(a)	GOOGLE’s obligation to pay royalties accrued or accruable; 

	 	(b)	Any cause of action or claim of GOOGLE or STANFORD, accrued or to accrue, because of any breach or default by the other party; and 

	 	(c)	The provisions of Articles 9 and 10 and any other provisions that by their nature are intended to survive. 

  

 -10- 

 17. EXPORT 
  
 GOOGLE warrants that GOOGLE will not export or reexport, directly or indirectly, to any country except when such export or reexport is authorized in full compliance with
the laws and regulations of the United States of America: 
  

	 	(a)	Software or any portion thereof; 

	 	(b)	Any direct product (including equipment, processes, or services) produced by use of Software; or 

	 	(c)	Any product of a complete plant or of a major component of a plant when such complete plant or such major component is the direct product of Software. 

  
 18. ASSIGNMENT 
  
 This Agreement may not be assigned without the written permission of STANFORD, except upon the acquisition of more than 50% of controlling
stock of GOOGLE by a third party by way of merger, asset sale or otherwise, or in connection with a reincorporation of GOOGLE or its affiliated entities. GOOGLE agrees to notify STANFORD of any such sale, merger or reincorporation. 
  
 19. ARBITRATION 
  
 19.1 Any controversy arising under or related to this Agreement, and any disputed claim by either party against the other
under this Agreement excluding any dispute relating to patent validity or infringement arising under this Agreement, shall be settled by arbitration in accordance with the Licensing Agreement Arbitration Rules of the American Arbitration
Association. 
  
 19.2 Upon request by either party, arbitration
will be by a third party arbitrator mutually agreed upon in writing by GOOGLE and STANFORD within thirty (30) days of such arbitration request. Judgement upon the award rendered by the arbitrator shall be final and nonappealable and may be entered
in any court having jurisdiction thereof. 
  
 19.3 The parties
shall be entitled to discovery in like manner as if the arbitration were a civil suit in the California Superior Court. The Arbitrator may limit the scope, time and/or issues involved in discovery. 
  
 19.4 Any arbitration shall be held at Stanford, California, unless the
parties hereto mutually agree in writing to another place. 
  

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 20. NOTICES 
  
 All notices under this Agreement are deemed fully given when written, addressed, and sent as follows: 
  
 All general notices to GOOGLE are mailed and e-mailed to: 
  

	 	Google	Inc. 

 Legal Department 
 2400 Bayshore Parkway 
 Mountain View, CA 94043 
 legal@google.com 
  
 All financial invoices to GOOGLE (i.e., accounting contact) are e-mailed to: 
  
 legalbilling@google.com 
  
 All general notices to STANFORD are e-mailed or mailed to: 
  
 Office of Technology Licensing 
 1705 El Camino Real 
 Palo Alto, CA 94306-1106 
 info@otlmail.stanford.edu 
  
 All payments to STANFORD are mailed to: 
  
 Stanford University 
 Office of Technology Licensing 
 Department #44439 
 P.O. Box 44000 
 San Francisco, CA 94144-4439 
  
 All progress reports to STANFORD are
e-mailed or mailed to: 
  
 Office of Technology
Licensing 
 1705 El Camino Real 
 Palo Alto, CA 94306-1106 
 info@otlmail.stanford.edu 
  
 Either party may change its address with written notice to the other party. 
  
 21. MISCELLANEOUS 
  
 21.1 Waiver. None of the terms of this Agreement can be waived except by the written consent of the party waiving
compliance. 
  
 21.2 Choice of Law. This Agreement and any
dispute arising under it is governed by the laws of the State of California, United States of America, applicable to agreements negotiated, executed, and performed within California. 
  
 21.3 Exclusive Forum. The state and federal courts having jurisdiction over Stanford, California, United States of
America, provide the exclusive forum for any court action between the parties relating to this Agreement. GOOGLE submits to the jurisdiction of such courts, and waives any claim that such a court lacks jurisdiction over GOOGLE or constitutes an
inconvenient or improper forum. 
  
 21.4 Headings. No
headings in this Agreement affect its interpretation. 
  

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 IN WITNESS WHEREOF, the parties hereto have executed this Agreement in duplicate originals by their duly authorized
officers or representatives. 
  

			
	 THE BOARD OF TRUSTEES OF THE LELAND
 STANFORD
JUNIOR UNIVERSITY

		
	Signature	 	/s/ Katharine Ku
		
	Name	 	Katharine Ku
		
	Title	 	Director, Technology Licensing
		
	Date	 	October 13, 2003

  

			
	GOOGLE INC.
		
	Signature	 	/s/ David C. Drummond
		
	Name	 	David C. Drummond
		
	Title	 	V.P. Corporate Development
		
	Date	 	October 4, 2003

  

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 Appendix A 
  

List of publications (http://google.stanford.edu/google_papers.html): 

	·	The Anatomy of a Large-Scale Hypertextual Web Search Engine by Sergey Brin and Lawrence Page. 

	·	Dynamic Data Mining: A New Architecture for Data with High Dimensionality by Sergey Brin and Lawrence Page. 

	·	The PageRank Citation Ranking: Bringing Order to the Web by Lawrence Page, Sergey Brin, Rajeev Motwani, and Terry Winograd. 

	·	Extracting Patterns and Relations from the World Wide Web by Sergey Brin. 

  
 Google search engine (http://google.stanford.edu) 

	·	[***] 

  
 Miscellaneous: 

	·	[***] 

  

 -14-Consulting Agreement between Insert Therapeutics and Dr. Mark Davis

 Exhibit 10.8 
  
 CONSULTING AGREEMENT 
  
 THIS AGREEMENT is made and entered into as of the 1st day of September, 2002 (the “Effective Date”), by and between Insert Therapeutics, Inc., a
Delaware corporation having its principal place of business at 2585 Nina Street, Pasadena, CA 91107 (the “Company”), and Mark Davis (“Consultant”). 
  
 RECITAL 
  
 As part of its ongoing program of research and development, the Company desires to engage individuals with scientific expertise to advise the Company
regarding the research and development of its proposed products. Consultant has the requisite expertise and is willing to serve as a consultant to the Company. 
  

Therefore, the Company and Consultant desire to enter into this Agreement. 
  
 AGREEMENT 
  
 In consideration of the foregoing and the mutual promises and covenants contained in this Agreement, the Company and Consultant agree to the following:

  
 1. ENGAGEMENT OF SERVICES; COMPENSATION. 
  
 Consultant agrees to provide consulting services to the Company, as described below
(collectively, the “Services”). The Services will include the use of Consultant’s creative talents to provide strategic business advice and to develop ideas, inventions, business contacts, discoveries, improvements, processes,
techniques, trade secrets and formulae relating to the development and commercialization of synthetic polymers for use primarily in drug delivery (the “Field”). The Services may also include, by way of example, the following: (a)
coordination of the progress and direction of the research and development activities of the Company, internally and with scientific collaborators; (b) attendance at meetings and assistance in making presentations and preparation of materials in
connection with scientific collaborations, industry meetings, fundraising efforts, due diligence investigations, etc.; and (c) other services within the general scope of the foregoing that might be typical of the responsibilities of a Chief
Scientific Officer, as requested by the CEO and other members of senior management of the Company. Generally, Consultant will make his services available the equivalent of one day per week, rendered when and as reasonably requested by the Company,
subject to prior commitments Consultant may have arising out of his academic duties at Caltech. The Company recognizes that Consultant may from time to time be unavailable to attend meetings or provide other consulting duties due to
Consultant’s other obligations, including but not limited to the performance of duties for other clients and employers, and attendance of scientific conferences. 
  
 2. COMPENSATION. 
  
 Provided that Consultant is not in breach or default hereunder, as full compensation for all Services rendered hereunder, and any and all rights granted or assigned to
Company by Consultant under this Agreement, Consultant shall receive a monthly retainer of $5,000.00, payable on the last day of each month in arrears. 

 3. CONFIDENTIAL INFORMATION; OWNERSHIP OF INVENTIONS. 
  
 Consultant acknowledges that he has signed separate Proprietary Information and Inventions
Agreements dated July 26, 2000, and November 2, 2000, in favor of the Company, and reaffirms that such agreements remains in full force and effect and are applicable to the Services and Consultant’s work for the Company under this Agreement.
The form and substance of said agreements is hereby incorporated by reference into this Agreement. The term “Inventions”, as used herein, will have the meaning given to such term in said Proprietary Information and Inventions Agreements.
Any conflicts between said agreements will be resolved in favor of the earlier-dated agreement. 
  
 4. INDEMNIFICATION. 
  
 4.1 Except as
otherwise provided below, Company will (i) indemnify Consultant and hold Consultant harmless from and against any losses, claims, damages, or liabilities, including without limitation judgments, fines and amounts paid in settlement (collectively
“losses”) resulting from any claim, action or proceeding against Consultant which arises out of or in connection with this Agreement and Consultant’s services rendered pursuant hereto (each, a “claim”), and (ii) pay, or
reimburse Consultant for, all costs and expenses (including without limitation counsel fees, court costs, witness fees and the costs and expenses of investigation) actually and reasonably incurred by Consultant in connection with preparing for or
defending any pending or threatened claim (collectively, “costs”). 
  
 4.2 The obligations of Company pursuant to the immediately preceding paragraph will not apply to any claim which results from the bad faith, gross negligence or willful misconduct of Consultant, and as to any such claim, Consultant will be
solely responsible for, and will indemnify Company and hold it harmless from and against, any associated losses or costs. 
  
 4.3 Consultant will exercise reasonable diligence in promptly notifying Company of any claim for which indemnification may be sought by Consultant and Company may, at its
written election, assume the defense of any such claim, including the selection and appointment of counsel and the defense or settlement thereof. If Company elects to assume defense of a claim, counsel chosen by Company will be subject to
Consultant’s approval, which will not be unreasonably withheld. Further, Company will not settle any action or claim in any manner which would include or constitute an admission by Consultant of liability, guilt in connection with the
commission of any crime or the violation of any statute, law, regulation or ordinance, or otherwise impose any penalty or limitation on Consultant without Consultant’s written consent, which may be given or withheld in Consultant’s sole
discretion. 
  
 4.4 The agreements and obligations of Company contained in this
Section 4 will continue during the term of this Agreement and thereafter so long as Consultant remains subject to any possible claim or threatened, pending or completed action, suit or proceeding arising out of or in connection with this Agreement
and Consultant’s services rendered pursuant to this Agreement. 
  
 5.
RETURN OF COMPANY PROPERTY. 
  
 Upon any termination of this Agreement
pursuant to Section 10, Consultant shall promptly deliver to the Company all property, documents and other materials of any nature in Consultant’s possession pertaining to the Services, together with all documents and other items containing or
pertaining to any Proprietary Information. Consultant shall not retain copies of any such documents or other materials after termination of this Agreement. Notwithstanding the foregoing, if, following the termination of this Agreement pursuant to
Section 10 below, Consultant continues to render 
  

 2 

 services or otherwise remains involved in the business of the Company in some other capacity (e.g., a director, advisory
board member or shareholder) in which capacity it is necessary or convenient for Consultant to retain any or all of such property, documents and other material, the provisions of this Section 5 will not apply to such property, documents or other
materials as the Consultant and Company agree may be so retained. 
  
 6.
OBLIGATION TO KEEP COMPANY INFORMED. 
  
 During the term of this Agreement,
Consultant shall promptly disclose to the Company, or any persons designated by it, fully and in writing and will hold in trust for the sole right and benefit of the Company any and all Inventions, whether or not patentable, of which Consultant
becomes aware that are in the Field; however, Consultant shall not be obligated to disclose information received by Consultant from others under a contractual obligation of confidentiality. 
  
 7. NO CONFLICTING OBLIGATION; PUBLICATION. 
  
 7.1 Consultant hereby certifies that his performance of all of the terms of this Agreement
and the Services will not breach or conflict with any agreement to keep the proprietary information of another entity in confidence. 
  
 7.2 Consultant certifies that Consultant has not and will not enter into any agreement either written or oral, in conflict with this Agreement. Absent a conflict of
interest, Consultant is free to provide Services to any other entity during the performance of this Agreement. 
  
 7.3 The provisions of this Agreement are subject to the understanding that Consultant is affiliated with the California Institute of Technology (the “Institution”), and must fulfill certain obligations
pursuant to the guidelines or policies adopted by the Institution. Consultant agrees to provide to the Company copies of such guidelines or policies, if any, promptly upon request by the Company. If Consultant is required to disclose any Inventions
to the Institution pursuant to applicable guidelines or policies, Consultant will promptly notify the Company of such obligation, specifying the nature of such disclosure and identifying the applicable guideline or policy under which disclosure is
required, prior to making such disclosure. 
  
 7.4 Consultant agrees to submit to
the Company any proposed publication that contains any discussion relating to the Company or Services performed by Consultant for the Company hereunder. The Company shall review and comment upon such publication within thirty (30) days of its
receipt thereof. Prior to the end of such thirty (30) day period, Consultant shall not submit such proposed publication to a third party unless the Company grants permission to Consultant therefor. If such publication discloses a Consultant
Invention, the Company may file a patent application on such Consultant Invention within such thirty (30) day period of time but shall not require any further delay in publication for such purpose, unless otherwise mutually agreed by the Company and
Consultant. Upon reasonable request by the Company, Consultant shall delete from such proposed publication any Proprietary Information other than information relating to a Consultant Invention that is included in such proposed publication, to third
parties for review and publication. After the expiration of such thirty (30) day period, Consultant may submit such proposed publication to third parties for review and publication, omitting any Proprietary Information other than a Consultant
Invention that the Company has reasonably requested Consultant to remove. This Section 7.4 shall not be construed to waive Consultant’s confidentiality obligations set forth in Section 4 with respect to Proprietary Information. 
  

 3 

 8. NO IMPROPER USE OF MATERIALS. 
  
 Consultant agrees not to bring to the Company or to use in the performance of Services any materials or documents of a present or former
employer of Consultant, or of Consultant’s employees, or any materials or documents obtained by Consultant under a binder of confidentiality imposed by reason of another of Consultant’s contracting relationships, unless such materials or
documents are generally available to the public or Consultant has authorization from such present or former employer or client for the possession and unrestricted use of such materials. Consultant understands that Consultant is not to breach any
obligation of confidentiality that Consultant has to present or former employers and agrees to fulfill all such obligations during the term of this Agreement. 
  

9. INDEPENDENT CONTRACTOR. 
  
 The Company and Consultant agree that Consultant is an independent contractor and not an agent or employee of the Company. Consultant has no authority to act on behalf of
the Company or obligate the Company by contract or otherwise. Consultant understands that Consultant will not be eligible for any employee benefits. The Company will not make deductions from Consultant’s fees for taxes; therefore, the payment
of any taxes related to Consultant’s provision of Services under this Agreement shall be the sole responsibility of Consultant. 
  
 10. TERM AND TERMINATION. 
  
 Unless previously terminated as set forth below, the term of this Agreement shall commence on the Effective Date and shall terminate one (1) year thereafter, subject to
renewal for additional one (1) year periods upon the mutual written consent of both parties. Notwithstanding the foregoing, this Agreement may be terminated, at the sole option of the Company, upon the Consultant’s death, disability, or
inability or unavailability to render the Services for any reason. If the Company elects so to terminate this Agreement, Company shall deliver written notice to the Consultant of such termination, which termination will become effective immediately,
and shall pay to Consultant, within 30 days of such termination the compensation due hereunder for services rendered through the date of termination. The “disability” of Consultant shall be deemed to occur if Consultant becomes physically
or mentally disabled, whether totally or partially, so that Consultant is substantially unable to perform the Services for such period as the Company may reasonably determine in light of any deadlines or delivery dates for which Consultant is
responsible 
  
 11. EFFECT OF TERMINATION. 
  
 Upon the expiration of this Agreement, each party shall be released from all obligations and
liabilities to the other occurring or arising after the date of such termination, except that any termination of this Agreement shall not relieve Consultant of Consultant’s obligations under Sections 5, 6, 7 and 8 hereof, or under the
Proprietary Information and Inventions Agreement incorporated by reference herein pursuant to Section 4, nor shall any such termination relieve Consultant or the Company from any liability arising from any breach of this Agreement or such
Proprietary Information and Inventions Agreement. 
  
 12. ASSIGNMENT.

  
 The rights and liabilities of the parties hereto shall bind and inure to
the benefit of their respective successors, assigns, heirs, executors and administrators, as the case may be; provided that Consultant may not assign or delegate Consultant’s obligations under this Agreement either in whole or in part without
the prior written consent of the Company. 
  

 4 

 13. LEGAL AND EQUITABLE REMEDIES. 
  
 Because Consultant’s services are personal and unique and because Consultant may have access to and become acquainted with the
proprietary information of the Company, the Company shall have the right to enforce this Agreement and any of its provisions by injunction, specific performance or other equitable relief without prejudice to any other rights and remedies that the
Company may have for a breach of this Agreement. 
  
 14. GOVERNING LAW;
SEVERABILITY. 
  
 This Agreement shall be governed by the laws of the State
of California as those laws are applied to contracts entered into and performed in California by California residents. If one or more of the provisions in this Agreement are deemed unenforceable by law, then such provision will be deemed stricken
from this Agreement and the remaining provisions will continue in full force and effect. 
  
 15. COMPLETE UNDERSTANDING; MODIFICATION. 
  
 This Agreement constitutes the final, exclusive and complete understanding and agreement of the parties hereto and supersedes all prior understandings and agreements. This Agreement is entered into without reliance upon any representation,
whether oral or written, not stated herein. Any waiver, modification or amendment of any provision of this Agreement shall be effective only if in writing and signed by a Company officer. 
  
 16. NOTICES. 
  
 Any notices required or permitted hereunder shall be given to the appropriate party at the address specified below or at such other address as the party shall specify in
writing. Such notice shall be deemed given upon personal delivery to the appropriate address or sent by certified or registered mail, three days after the date of mailing. 
  
 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the Effective Date. 
  

					
	Consultant	 	Insert Therapeutics, Inc.
			
	 /s/ Mark Davis

	 	 By:
	 	 /s/ Leonard Borrmann

	 Mark Davis
	 	 	 	 Leonard Borrmann, President and CEO

			
	 Address:
	 	 	 	 Address:

			
	 2585 Nina Street
	 	 	 	 2585 Nina Street

	 Pasadena, CA 91107
	 	 	 	 Pasadena, CA 91107

  

 5

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