Document:

EX-10.27

 Exhibit 10.27 
 FOURTH AMENDMENT TO LEASE AGREEMENT 
 This Fourth Amendment to Lease
Agreement (this “Amendment”) is executed as of the Effective Date (as hereinafter defined) between Riverchase Capital, LLC, a Florida limited liability company, and Stow Riverchase, LLC, a Florida limited liability company,
successors in interest to RBP, LLC, (collectively “Landlord”), and BioCryst Pharmaceuticals, Inc., (“Tenant”) dated July 13, 2000, and amended May 15, 2001, November 14, 2005, and August 7,
2007, (collectively the “Lease”), for the Premises commonly known as Suites A,B&H of the 2190 Wing, and Suites A&C of the 2192 Wing of Building 2190/2192, Riverchase Business Park, Birmingham, Alabama, 35244. 

PRELIMINARY STATEMENTS 
 Landlord and Tenant desire to enter into this Amendment for the purpose of downsizing the Premises, and for the purposes set forth herein. 

AGREEMENTS: 
 NOW,
THEREFORE, in consideration of these premises and other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, Landlord and Tenant hereby agree to amend the Lease as follows: 

 

	1.	Definitions. Unless otherwise defined herein, all capitalized terms used in this Amendment shall have the meaning ascribed to them in the Lease.

  

	2.	Premises. Effective February 1, 2012, the Premises is reduced to 34,100 sf as referenced in Exhibit A to this Amendment as “BioCryst Premises.”
Tenant’s proportionate share of the Building as used by the Landlord in the calculations of Common Area Maintenance Costs and Taxes as outlined in the Lease shall remain unchanged from its current amount of 73.59%. Notwithstanding the
foregoing, Tenant shall not be responsible for charges related to any services incurred or specifically requested by Nohab (including, without limitation, special cleaning requests etc.). Tenant shall pay $12,000.00 towards the separation of the
BioCryst Premises and the Nohab Premises. Nohab will be responsible for separating the electrical service between the BioCryst Premises and the Nohab Premises. Tenant and Landlord will contribute up to $15,000.00 each towards the separation
after receipt of copies of paid invoices and signed lien waiver(s) from the responsible contractor. 

  

	3.	Nohab Lease. Tenant acknowledges that Landlord and Nohab Business Products, LLC (“Nohab”) have entered into a Lease Agreement for 16,050 sf of
Tenant’s Premises as shown on the attached Exhibit A to this Amendment (“Nohab Premises”). 

  

	4.	Common Area Maintenance Costs and Taxes. Tenant shall remain responsible for all Common Area Maintenance Costs and Taxes for both BioCryst Premises and for Nohab
Premises through June 30, 2015. 

  

	5.	Sub-Metered Electric. Tenant, Landlord, and Nohab acknowledge that Nohab’s electric usage will be metered through the installation of sub-meters within
Tenant’s Premises. Tenant shall read the sub-meters quarterly and at such time that Nohab’s usage exceeds $2,675 per month, Tenant shall invoice Nohab, and Nohab shall pay to Tenant the difference. If Nohab’s usage is less than $2,675
per month, Tenant shall issue a credit to Nohab for the difference. 

  

	6.	Fixed Minimum Rent Payment. 

  

					
	 Dates:
	  	Rent:	 
	 2/1/12 – 2/29/12
	  	$	43,992.42	  
	 3/1/12 – 6/30/12
	  	$	35,967.42	  
	 7/1/12 – 3/31/13
	  	$	37,287.20	  
	 4/1/13 – 6/30/13
	  	$	33,274.70	  
	 7/1/13 – 6/30/14
	  	$	34,634.06	  
	 7/1/14 – 6/30/15
	  	$	36,034.21	  

  

	7.	Renewal Option. The Option to Renew provision provided for in the Third Amendment to Lease Agreement remains in full force and effect; however, shall only apply
to the new reduced Premises size of 34,100 sf. 

	8.	Ratification. Tenant hereby ratifies and confirms its obligations under the Lease, and represents and warrants to Landlord that it has no defenses thereto.
Additionally, Tenant further confirms and ratifies that, as of the date hereof, (a) the Lease is and remains in good standing and in full force and effect, and (b) Tenant has no claims, counterclaims, set-offs or defenses against Landlord
arising out of the Lease or in any way relating thereto or arising out of any other transaction between Landlord and Tenant. 

  

	9.	Binding Effect; Governing Law. Except as modified hereby, the Lease shall remain in full effect and this Amendment shall be binding upon Landlord and Tenant.
This Amendment shall be governed by the laws of the State of Alabama. The “Effective Date” shall be the date the last of Landlord and Tenant signs this Amendment as evidenced by the date below their respective signatures.

  

	10.	Conflict. In the event of a conflict between the terms and conditions of this Amendment and the terms and conditions of the Lease, this Amendment shall control
and prevail. 

  

	11.	Severability and Invalidity. If any provision of this Amendment, or the application of such provision to any person or circumstance, shall be held invalid, the
remainder of the Amendment, or the application of such provision to persons or circumstances other than those to which it is held invalid, shall not be affected thereby 

 

	12.	Brokers. Tenant and Landlord represent and warrant to the other that there is no other broker, agent or finder involved in this transaction, other than Engel
Realty Company, LLC (“Engel”), Platinum Realty (“Platinum”) and Sandner Commercial Real Estate, Inc. (“Sandner”), to whom Tenant shall pay a commission for the Nohab Lease period January 1, 2012 through
June 30, 2015 pursuant to a separate written agreement. All shall be paid by Tenant based on the gross base rent lease value, as follows; 2% payable to Engel and 2% to Platinum, and 2% to Sandner. Therefore, the total commission due is
$26,482.50. Tenant agrees to defend, indemnify Landlord and hold Landlord harmless of and from all liabilities and/or liens arising out of a breach of the foregoing representation and warranty. 

All other terms and covenants of the original Lease agreement shall remain as contained. 

SIGNATURES ON FOLLOWING PAGE 

  
 2 

 IN WITNESS WHEREOF, the parties hereto have set their hands and seals as of the Effective Date. 

 

									
	“TENANT”	 		 	Signed, sealed and delivered in my presence as witness to Tenant:
			
	Tenant Name: BioCryst Pharmaceuticals, Inc.	 		 	Witness for Tenant
				
	 Business Type: Corporation 
  
	 		 	Signature:	 	 /s/ Whitney A. Meeks

	State of Organization: Alabama 	 		 	Print Name: Whitney A. Meeks
					
	Signature:	 	 /s/ Alane Barnes
	 		 		 	
	Print Name: 	 	Alane Barnes	 		 		 	
	Title: 	 	General Counsel	 		 		 	
				
	Date: 2/23/02	 		 		 	
			
	“LANDLORD”	 		 	Signed, sealed and delivered in my presence as witness to Landlord
			
	 Riverchase Capital, LLC, 
 a Florida Limited Liability Company
	 		 	Witness 1 for Landlord
					
	Signature:	 	 /s/ Kristen Kennedy Showalter
	 		 	Signature:	 	 /s/ Lisa I. Cadieux

		 	 Kristen Kennedy Showalter

Vice President
	 		 	Print Name:	 	Lisa I. Cadieux
				
	Date: 3/23/12	 		 		 	
			
	 Stow Riverchase, LLC,
 a Florida Limited Liability Company 
  
 By: Arcis Realty, LLC, as its attorney-in-fact
	 		 	Witness 1 for Landlord
					
	Signature:	 	 /s/ Kristen Kennedy Showalter
	 		 	Signature: 	 	 /s/ Lisa I. Cadieux

		 	Kristen Kennedy Showalter	 		 	Print Name: Lisa Cadieux
		 	Vice President	 		 		 	

 Date: 3/23/12 
  

			
	 Agreed & Accepted By:
 Nohab Business Products, LLC

	
	 /s/ [Signature Illegible]

	Signature
		
	By:	 	[Illegible]
	Its:	 	CFO
	Date: 2/28/12

  
 3 

 Exhibit A 
 Premises 
  
 

 

  
 4EX-10.30

 Exhibit 10.30 
 FOURTH AMENDMENT TO AMENDED AND RESTATED CREDIT AGREEMENT 
 This FOURTH
AMENDMENT TO AMENDED AND RESTATED CREDIT AGREEMENT (this “Amendment”), dated as of March 8, 2013 (the “Execution Date”), is entered into by and among CONSTELLATION ENERGY PARTNERS LLC, a Delaware
limited liability company (the “Borrower”), and the Lenders signatory hereto (the “Lenders”), and THE ROYAL BANK OF SCOTLAND plc, as Administrative Agent (the “Administrative
Agent”) and as Collateral Agent (the “Collateral Agent”). 
 RECITALS 

WHEREAS, the Borrower, the Lenders and The Royal Bank of Scotland plc, as Administrative Agent and a Lender, are party to that certain
Amended and Restated Credit Agreement dated as of November 13, 2009, as amended by that certain First Amendment to Amended and Restated Credit Agreement dated as of February 11, 2010, that certain Second Amendment to Amended and Restated
Credit Agreement dated as of June 3, 2011 and that certain Third Amendment to Amended and Restated Credit Agreement dated as of February 1, 2013 (such Amended and Restated Credit Agreement, as the same may from time to time be amended,
modified, supplemented or restated, herein called the “Credit Agreement”). Terms used and not otherwise defined herein shall have the respective meanings assigned to such terms in the Credit Agreement, and the provisions of
Section 1.03 of the Credit Agreement are incorporated herein by reference; 
 WHEREAS, the Borrower and the Lenders seek to
clarify the definition of “Debt”; and 
 WHEREAS, the parties hereto have agreed, subject to the terms and conditions
hereinafter set forth, to amend the Credit Agreement as set forth below. 
 NOW, THEREFORE, in consideration of the mutual
covenants and agreements herein contained and for other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the parties hereto hereby agree as follows: 

SECTION 1. Amendments to the Credit Agreement. Subject to Section 4 of this Amendment, the Credit Agreement is
hereby amended by deleting the definition of “Debt” in Section 1.02 of the Credit Agreement in its entirety and substituting the following in place thereof: 

““Debt” means, for any Person, the sum of the following (without duplication): (a) all
obligations of such Person for borrowed money or evidenced by bonds, bankers’ acceptances, debentures, notes or other similar instruments; (b) all obligations of such Person (whether contingent or otherwise) in respect of letters of
credit, surety or other bonds and similar instruments; (c) all accounts payable, accrued expenses, liabilities or other obligations of such Person, in each such case to pay the deferred purchase price of Property or services; (d) all
obligations under Capital Leases; (e) all obligations under Synthetic Leases; (f) all Debt (as defined in the other clauses of this definition) of others secured by (or for which the holder of such Debt has an existing right, contingent or
otherwise, to be secured by) a Lien on any Property of such Person, whether or not such Debt is assumed by such Person; (g) all Debt (as defined in the other clauses of this definition) of others guaranteed by such Person or in which such
Person otherwise assures a creditor against loss of the Debt (howsoever such assurance shall be made) to the extent of the lesser of the amount of such Debt and the maximum stated amount of such 

 
guarantee or assurance against loss; (h) all obligations or undertakings of such Person to maintain or cause to be maintained the financial position or covenants of others or to purchase the
Debt or Property of others; (i) obligations to deliver commodities, goods or services, including, without limitation, Hydrocarbons, in consideration of one or more advance payments, other than gas balancing arrangements in the ordinary course
of business; (j) obligations to pay for goods or services whether or not such goods or services are actually received or utilized by such Person; (k) any Debt of a partnership for which such Person is liable either by agreement, by
operation of law or by a Governmental Requirement but only to the extent of such liability; (l) Disqualified Capital Stock; and (m) the undischarged balance of any production payment created by such Person or for the creation of which such
Person directly or indirectly received payment; provided however, Debt shall exclude (i) all obligations under Swap Agreements and (ii) for purposes of calculating Total Net Debt, accounts payable and other accrued liabilities (for
the deferred purchase price of Property or services) from time to time incurred in the ordinary course of business which are not greater than sixty (60) days past the date of invoice or delinquent or which are being contested in good faith by
appropriate action and for which adequate reserves are maintained in accordance with GAAP and other obligations to pay for goods or services whether or not such goods or services are actually received or utilized by such Person. The Debt of any
Person shall include all obligations of such Person of the character described above to the extent such Person remains legally liable in respect thereof notwithstanding that any such obligation is not included as a liability of such Person under
GAAP.” 
 SECTION 2. Agreement Regarding this Amendment. The parties hereto acknowledge and agree that upon
satisfaction of the conditions in Section 4 of this Amendment, this Amendment shall be effective as of November 13, 2009. 
 SECTION 3. Representations and Warranties. The Borrower represents and warrants as follows: 
 (a) The Borrower is duly authorized and empowered to execute, deliver and perform this Amendment and all other instruments referred to or mentioned herein to which it is a party, and all action on its
part requisite for the due execution, delivery and the performance of this Amendment has been duly and effectively taken. 
 (b)
After giving effect to this Amendment, the representations and warranties contained in the Credit Agreement, as amended hereby, and any other Loan Documents executed in connection herewith or therewith are true in all material respects on and as of
the date hereof as though made on and as of the date hereof, except to the extent that such representation or warranty was made as of a specific date, in which case such representation or warranty was true in all material respects when made.

 (c) After giving effect to this Amendment, no event has occurred and is continuing which constitutes a Default. 

(d) When this Amendment is duly executed and delivered, the Credit Agreement as amended by this Amendment will be legal and binding
obligations of the Borrower, enforceable in accordance with their respective terms, except as limited by bankruptcy, insolvency or similar laws of general application relating to the enforcement of creditors’ rights and by equitable principles
of general application. 

 SECTION 4. Conditions to Effectiveness. 

(a) This Amendment shall become effective when, and only when, the Administrative Agent shall have received the following: 

(i) counterparts of this Amendment duly executed and delivered on behalf of the Borrower and all Lenders; 

(ii) a Secretary’s Certificate of the Borrower, including resolutions authorizing the execution, delivery and
performance of this Amendment and any other documents signed in connection therewith, and the Borrower’s articles of formation, evidence of existence and good standing, and incumbency certificate, all in form and substance satisfactory to the
Administrative Agent; 
 (iii) the Ratification and Affirmation of Guarantors duly executed and delivered on
behalf of the Guarantors; 
 (iv) such other documents, instruments and agreements as the Administrative Agent
reasonably deems necessary, in form and substance reasonably satisfactory to the Administrative Agent; and 
 (v)
all fees and other amounts due and payable, including to the extent invoiced, reimbursement or payment of all out-of-pocket expenses required to be reimbursed or paid by the Borrower pursuant to Section 8. 

(b) No Default or Event of Default exists on the Execution Date or will arise as a result of the execution and effect of this Agreement.

 SECTION 5. Reference to and Effect on Loan Documents. 

(a) On and after the effective date of this Amendment, each reference in the Credit Agreement to “this Agreement,”
“hereunder,” “hereof,” “herein” or any other expression of like import referring to the Credit Agreement, and each reference in the other Loan Documents to “the Credit Agreement,” “thereunder,”
“thereof,” “therein” or any other expression of like import referring to the Credit Agreement, shall mean and be a reference to the Credit Agreement as amended by this Amendment. 

(b) Except as specifically amended above, the Credit Agreement and the other Loan Documents shall remain in full force and effect and are
hereby ratified and confirmed. Without limiting the generality of the foregoing, the Security Instruments and all of the Collateral described therein do and shall continue to secure the payment of all obligations stated to be secured thereby under
the Credit Agreement, as amended hereby, and the other Loan Documents. 
 (c) The execution, delivery and effectiveness of this
Amendment shall not operate as a waiver of any right, power or remedy of the Lenders under any of the Loan Documents or constitute a waiver of any provision of any of the Loan Documents. 

SECTION 6. Execution in Counterparts. This Amendment may be executed in any number of counterparts and by the parties hereto in
separate counterparts, each of which when so executed and delivered shall be deemed to be an original and all of which taken together shall constitute one and the same agreement. 

 SECTION 7. Governing Law. THIS AMENDMENT SHALL BE GOVERNED BY, AND CONSTRUED IN
ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW YORK WITHOUT REFERENCE TO THE CHOICE OF LAW PRINCIPLES THEREOF. 
 SECTION 8.
Costs and Expenses. The Borrower agrees to pay on demand all out of pocket costs and expenses of the Administrative Agent in connection with the preparation, reproduction, execution and delivery of this Amendment and the other instruments and
documents to be delivered hereunder, including reasonable legal fees and expenses for counsel for the Administrative Agent 

[Signature pages follow] 

 The parties hereto have caused this Amendment to be executed by their respective duly
authorized representatives as of the date first written above. 
  

			
	CONSTELLATION ENERGY PARTNERS LLC
		
	By:	 	/s/ Charles C. Ward
		 	Charles C. Ward, Chief Financial Officer and Treasurer

							
	 26.829268% of Outstanding Principal
 Amount of the Loans
	 		 	 THE ROYAL BANK OF SCOTLAND plc, as Administrative Agent, Collateral Agent and as a Lender

 
 By: RBS Securities Inc., as agent

				
		 		 	 By:
	 	/s/ Sandra Aultman
		 		 		 	Sandra Aultman, Managing Director

							
	 21.951220% of Outstanding Principal
 Amount of the Loans
	 		 	THE BANK OF NOVA SCOTIA, as a Lender
				
		 		 	By:	 	/s/ Terry Donovan
		 		 		 	Terry Donovan, Managing Director

							
	 21.951220% of Outstanding Principal
 Amount of the Loans
	 		 	WELLS FARGO BANK, N.A., as a Lender
				
		 		 	By:	 	/s/ Richard Hawthorne
		 		 		 	Richard Hawthorne, Director

							
	 14.634146% of Outstanding Principal
 Amount of the Loans
	 		 	ING Capital LLC, as a Lender
				
		 		 	By:	 	/s/ Charles Hall
		 		 		 	Charles Hall, Managing Director

							
	 14.634146% of Outstanding Principal
 Amount of the Loans
	 		 	SOCIÉTÉ GÉNÉRALE, as a Lender
				
		 		 	By:	 	/s/ Elena Robciuc
		 		 		 	Elena Robciuc, Managing Director

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