Document:

Agreement

 Exhibit 10.43 
  
 AGREEMENT (this “Agreement”), dated as of December 1, 2003, by and between Columbia Laboratories, Inc. (the
“Corporation”), and Perry Corp., a New York Corporation, with principal executive offices located at 599 Lexington Avenue, New York, NY 10022 (“Investor”). Capitalized terms used and not otherwise defined in this Agreement have
the meanings respectively ascribed thereto in the Rights Agreement, dated as of March 13, 2002, between the Corporation and First Union National Bank, as rights agent (as amended from time to time, the “Rights Agreement”). 
  
 1. Investor hereby represents and warrants to the Corporation that, as of the
close of business on the date of this Agreement, Investor, its Affiliates and Associates Beneficially Own less than 15% of the outstanding shares of Common Stock. 
  
 2. (a) The Corporation hereby represents and warrants to Investor that the board of directors of the Corporation has
approved, solely for purposes of clause (ii)(A) of the first proviso of the definition of “Acquiring Person” in the Rights Agreement, the Investor, together with its Affiliates and Associates, becoming the Beneficial Owner, in the
aggregate, of up to, but not more than, an aggregate of 19.9% of the outstanding Voting Stock, subject to (i) Beneficial Ownership of such stock having been acquired by Investor and its Affiliates and Associates prior to April 1, 2004, (ii)
compliance by Investor and its Affiliates and Associates with the provisions of this Agreement and (iii) Investor and its Affiliates and Associates being eligible to report Beneficial Ownership of all such stock on Schedule 13G under the Exchange
Act and not being required to report such ownership on Schedule 13D under the Exchange Act. 
  
 (b) For the avoidance of doubt, the parties acknowledge and agree that the approval of the Corporation’s board of directors described
in Section 2(a) hereof is not intended to constitute approval for purposes of Section 203 of the Delaware General Corporation Law (“DGCL 203”) or intended to make the limitations and requirements of DGCL 203 inapplicable to Investor, its
Affiliates and Associates or any “business combination” (as defined in DGCL 203) involving any of them and the Corporation (and, in any event (and without in any way limiting Section 3 hereof), Investor, on behalf of itself and its
Affiliates and Associates, agrees that the requirements of DGCL 203 shall apply to any such business combination irrespective of the approval described in Section 2(a) hereof and as if such approval was never given). 
  
 3. Investor hereby covenants and agrees that, for a period of eighteen (18)
months from the date of this Agreement, neither Investor nor any of its Affiliates or Associates shall, directly or indirectly, in any manner: (a) acquire, offer or propose to acquire, solicit an offer to sell or agree to acquire, directly or
indirectly, alone or in concert with others, by purchase or otherwise, any direct or indirect beneficial interest in any voting securities of the Corporation or direct or indirect rights, warrants or options to acquire, or securities convertible
into or exchangeable for, any voting securities of the Corporation (other than acquisitions of (i) Common Stock in accordance with Section 2(a) hereof if, after giving effect to such acquisitions, Investor, its Affiliates and Associates do not, in
the aggregate, at any time Beneficially Own in the aggregate more 

 than 19.9% of the Voting Stock then outstanding or (ii) securities of the Corporation obtained pursuant to a share
dividend or similar involuntary acquisition of such securities); (b) make, or in any way participate in, directly or indirectly, alone or in concert with others, any “solicitation” of “proxies” to vote (as such terms are used in
the proxy rules of the Securities and Exchange Commission promulgated pursuant to Section 14 of the Exchange Act) or seek to advise or influence in any manner whatsoever any Person with respect to the voting of any voting securities of the
Corporation; (c) form, join or any way participate in a “group” within the meaning of Section 13(d)(3) of the Exchange Act with respect to any voting securities of the Corporation; (d) acquire, offer to acquire or agree to acquire,
directly or indirectly, alone or in concert with others, by purchase, exchange or otherwise, any of the assets, tangible or intangible, of the Corporation or any of its subsidiaries, or direct or indirect rights, warrants or options to acquire any
assets of the Corporation or any of its subsidiaries, except for such assets as are then being offered for sale by the Corporation or any of its subsidiaries; (e) arrange, or in any way participate, directly or indirectly, in any financing for the
purchase of any voting securities of the Corporation or any securities convertible into or exchangeable or exercisable for any voting securities or assets of the Corporation, except for such assets as are then being offered for sale by the
Corporation or any of its subsidiaries; (f) otherwise act, alone or in concert with others, to seek to propose to the Corporation or any of its stockholders any liquidation, merger, business combination, restructuring, recapitalization or other
transaction to or with the Corporation or otherwise seek, alone or in concert with others, to control or change the management, board of directors or policies of the Corporation or nominate any person as a director who is not nominated by the then
incumbent directors, or propose any matter to be voted upon by the stockholders of the Corporation; (g) otherwise act, alone or in concert with others, to seek to influence the management, board of directors or policies of the Corporation (provided
that this clause (g) shall not restrict the ability of the Investor, its Affiliates and Associates to have conversations with members of management and the board of directors regarding operational and financing matters in the ordinary course of the
business of the Corporation to the extent that and so long as the conversations are not otherwise inconsistent with the other provisions of this Section 3); (h) make any request or proposal to amend, waive or terminate any provision of this Section
3; or (i) take any action that might result in the Corporation having to make a public announcement regarding any of the matters referred to in clauses (a) through (h) of this Section 3, or announce an intention to do, or enter into any arrangement
or understanding or discussions with others to do, any of the actions restricted or prohibited under such clauses (a) through (h) of this Section 3. Notwithstanding anything contained herein to the contrary, the Investor, its Affiliates and
Associates shall not be in breach of this Agreement if the Investor, together with its Affiliates and Associates, becomes the Beneficial Owner of greater than 19.9% of the outstanding Voting Stock and such increase is solely the result of a
reduction of the outstanding shares of Voting Stock pursuant to a transaction or a series of related transactions consummated by the Corporation (including, without limitation, repurchases of Voting Securities by the Corporation). 
  

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 4. The Corporation shall be permitted to publicly disclose this Agreement. In the event of an actual or
threatened violation of this Agreement, Investor hereby expressly consents, on behalf of itself and its Affiliates or Associates, to the enforcement of this Agreement by injunctive relief or specific performance, without proof of actual damages or
any requirement to post a bond, in addition to any and all other remedies available to the Corporation. Investor shall indemnify the Corporation and the Corporation’s directors and officers from, and hold them harmless in respect of, any
losses, liabilities, damages, costs and expenses (including reasonable attorneys’ fees and expenses) arising out of or incurred in connection with (a) any breach or threatened breach (provided that such threat must be based on a reasonable good
faith determination by the Company under the circumstances) by Investor or any of its Affiliates or Associates of any provision of this Agreement. 
  
 5. (a) This Agreement constitutes the entire agreement between the parties with respect to the subject matter hereof. Except as set forth in the last
sentence of Section 4 hereof, this Agreement is not intended to and shall not confer upon any Person other than the parties hereto any rights hereunder. Neither this Agreement nor any of the rights or obligations hereunder shall be assigned by
Investor (whether by operation of law or otherwise) without the prior written consent of the Corporation, and any purported assignment without such consent shall be null and void. Subject to the preceding sentence, this Agreement shall be binding
upon and shall inure to the benefit of the parties hereto and their respective successors and permitted assigns. This Agreement may not be amended or supplemented, except by a written agreement executed by each of the parties hereto. No failure or
delay by the Corporation in exercising any right hereunder shall operate as a waiver thereof nor shall any single or partial exercise thereof preclude any other or further exercise thereof or the exercise of any other right hereunder. Any waiver by
the Corporation hereunder shall be valid only if set forth in an instrument in writing signed on behalf of the Corporation. This Agreement may be executed in counterparts, all of which taken together shall constitute one and the same agreement.

  
 (b) This Agreement shall be governed by and
construed in accordance with the laws of the State of New York, without regard to the principles of conflicts of laws thereof. Investor, on behalf of itself and each of its Affiliates and Associates, and the Corporation, (i) consents to submit to
the personal jurisdiction of any federal court of the United States located in the State of New York or any New York State court in any action, suit or proceeding arising out of or relating to this Agreement (an “Action”), (ii) irrevocably
waives any objection to the laying of venue of any Action in any such courts, agrees not to plead or claim that any Action in any such court has been brought in an inconvenient forum, and agrees not to attempt to deny or defeat such personal
jurisdiction by motion or other request for leave from any such court, and (iii) irrevocably waives any and all rights to trial by jury in any Action. 
  
 (c) In the event that any term or provision of this Agreement is determined by a court of competent jurisdiction to be invalid or
unenforceable for any reason, in whole or in part, the remaining terms and provisions of this Agreement shall be 
  

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 unaffected thereby and shall remain in full force and effect to the fullest extent permitted by applicable law, and such
invalid or unenforceable term or provision shall be deemed replaced by a term or provision that is valid and enforceable and that comes closest to expressing the Corporation’s intention with respect to such invalid or unenforceable term or
provision. 
  
 IN WITNESS WHEREOF, the parties have caused this
Agreement to be duly executed as of the date first above written. 
  

	COLUMBIA LABORATORIES, INC.
		
	 By:
	 	             /s/    Robert S. Mills            

	 Name:
	 	Robert S. Mills
	 Title:
	 	Senior Vice President & Chief Operating Officer
	 	 	 
	 PERRY CORP.

		
	 By:
	 	             /s/    Richard Perry            

	 Name:
	 	Richard Perry
	 Title:
	 	President

  

 4Specimen of Stock Certificate representing the Series F

 EXHIBIT 4.1 
  

	 	  	 HEALTH CARE PROPERTY INVESTORS, INC.
 Incorporated under the laws of the State of Maryland
	  	 ********* SHARES
  

	 NUMBER                            
  
 __________
	  	7.1% Series F Cumulative Redeemable Preferred Stock	  	 SEE REVERSE FOR CERTAIN DEFINITIONS
 AND IMPORTANT NOTICE OF TRANSFER
 RESTRICTIONS AND OTHER
INFORMATION
  
 CUSIP: 421915 12 5

  
 THIS IS TO CERTIFY
THAT 
  
 ************ 
  
 is the record holder of   *********** 
  
 FULLY PAID AND NON-ASSESSABLE SHARES OF 7.1% SERIES F CUMULATIVE REDEEMABLE PREFERRED
STOCK, PAR VALUE $1.00 PER SHARE, OF 
  
 HEALTH CARE
PROPERTY INVESTORS, INC., transferable on the books of the Corporation by the holder hereof, in person or by duly authorized attorney, upon surrender of this Certificate duly endorsed. This Certificate is not valid until countersigned by the
Transfer Agent and Registrar. 
  
 In Witness Whereof, the
Corporation has caused this Certificate to be signed in facsimile by its duly authorized officers and a facsimile of its corporate seal. 
  
 Dated
                                        
                         
  

	 Countersigned and Registered
 The Bank of New
York, Transfer Agent and Registrar
  
 By:________________________________________
       Authorized Signature
	 	  
 [Corporate Seal]
	 	                                      
                                        
                                     
 Chairman
  
                                       
                                        
                                    
 Senior Vice President, General Counsel and Corporate Secretary

  

 CLASSES OF STOCK 
  
 The Corporation is authorized to issue more than one class of capital stock consisting of Common Stock and one or more
series of Preferred Stock. The Board of Directors is authorized to determine the preferences, limitations and relative rights of each series of Preferred Stock before the issuance of any such series of Preferred Stock. The Corporation will furnish,
without charge, to any stockholder making a request therefor, a copy of the Corporation’s Charter and a full statement with respect to designations and any preferences, conversion or other rights, voting powers, restrictions, limitations as to
dividends and other distributions, qualifications and terms and conditions of redemption of the stock of each class which the Corporation has the authority to issue and, since the Corporation is authorized to issue Preferred Stock in series, (i) the
differences in the relative rights and preferences between the shares of each series to the extent set, and (ii) the authority of the Board of Directors to set such rights and preferences of subsequent series. Request for such written statement may
be directed to the Secretary of the Corporation at its principal office. 
  
 RESTRICTION ON OWNERSHIP AND TRANSFER 
  
 The shares of Series F Preferred Stock represented by this certificate are subject to restrictions on beneficial and constructive ownership and transfer for the purpose of the Corporation’s maintenance of its
status as a real estate investment trust under the Internal Revenue Code of 1986, as amended (the “Code”). Subject to certain further restrictions and except as expressly provided in the Articles Supplementary for the Series F Preferred
Stock, (i) no person may beneficially own shares of the Corporation’s Series F Preferred Stock in excess of 9.8% (by value or by number of shares, whichever is more restrictive) of the outstanding Series F Preferred Stock of the Corporation;
(ii) no person may constructively own shares of the Corporation’s Series F Preferred Stock in excess of 9.8% (by value or by number of shares, whichever is more restrictive) of the outstanding Series F Preferred Stock of the Corporation; (iii)
no person may beneficially or constructively own Series F Preferred Stock that, taking into account any other capital stock of the Corporation beneficially or constructively owned by such person, would result in the Corporation being “closely
held” under Section 856(h) of the Code or otherwise cause the Corporation to fail to qualify as a REIT; and (iv) no person may transfer Series F Preferred Stock if such transfer would result in the capital stock of the Corporation being owned
by fewer than 100 persons. Any person who beneficially or constructively owns or attempts to beneficially or constructively own Series F Preferred Stock which causes or will cause a person to beneficially or constructively own Series F Preferred
Stock in excess of the above limitations must immediately notify the Corporation. If any of the restrictions on transfer or ownership are violated, the Series F Preferred Stock represented hereby in excess of such restrictions will be automatically
transferred to the trustee of a trust for the benefit of one or more charitable beneficiaries. In addition, the Corporation may redeem shares upon the terms and conditions specified by the Board of Directors in its sole discretion if the Board of
Directors determines that ownership or a transfer or other event may violate the restrictions described above. Furthermore, upon the occurrence of certain events, attempted transfers in violation of the restrictions described above may be void ab
initio. All terms in this legend which are defined in the Articles Supplementary for the Series F Preferred Stock shall have the meanings ascribed to them in such Articles Supplementary, as the same may be amended from time to time, a copy of which,
including the restrictions on transfer and ownership, will be furnished to each holder of Series F Preferred Stock on request and without charge. Requests for such a copy may be directed to the Secretary of the Corporation at its principal office.

  
 The following abbreviations, when used in the
inscription on the face of this certificate, shall be construed as though they were written out in full according to applicable laws or regulations: 
  

	TEN COM	 	- as tenants in common	 	UNIF GIFT MIN ACT	 	 -
                     Custodian
                            

	TEN ENT	 	- as tenants by the entireties	 	 	 	                (Cust)                      
          (Minor)
	JT TEN	 	 - as joint tenants with right
   of
survivorship and not as
   tenants in common
	 	 	 	   under Uniform Gifts to Minors
   Act
                                    
                     (State)

  
 Additional
abbreviations may also be used though not in the above list. 
  
 For value
received,
                                        
                                     hereby sell, assign and
transfer unto 
  

	   PLEASE INSERT SOCIAL SECURITY OR OTHER
           IDENTIFYING NUMBER OF ASSIGNEE

	

	 
	

  
                                       
                                        
                                        
                                        
                                        
                                        
                    
 (PLEASE PRINT OR
TYPEWRITE NAME AND ADDRESS, INCLUDING ZIP CODE, OF ASSIGNEE) 
                                       
                                        
                                        
                                        
                                        
                                        
                    
                                       
                                        
                                        
                                        
                                        
                                        
                    
                                       
                                        
                                        
                                        
                                        
                                        
       shares 
 of the 7.1% Series F Cumulative Redeemable Preferred Stock represented by the within Certificate, and
do hereby irrevocably constitute and appoint 
                                       
                                        
                                        
                                        
                                        
                                     Attorney to

 transfer the said stock on the books of the within named Corporation with full power of substitution in the premises. 
  
 DATED
                                        

  

	 	  	 X

	 	  	X
	 	  	

	 NOTICE:
	  	THE SIGNATURE TO THIS ASSIGNMENT MUST CORRESPOND WITH THE NAME(S) AS WRITTEN UPON THE FACE OF THE CERTIFICATE IN EVERY PARTICULAR, WITHOUT ALTERATION OR ENLARGEMENT OR ANY CHANGE
WHATEVER.

  

	
	 Signature(s) Guaranteed:                                 
                                        
                                        
                                        
                                        
                

	 THE SIGNATURE(S) MUST BE GUARANTEED BY AN ELIGIBLE GUARANTOR INSTITUTION (BANKS,
BROKERS,
 SAVINGS ASSOCIATIONS AND CREDIT UNIONS WITH MEMBERSHIP IN AN APPROVED SIGNATURE
 GUARANTEE MEDALLION PROGRAM), PURSUANT TO S.E.C. RULE 17Ad-15.

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