Document:

Exhibit 10.8

 

 

July 20, 2017

 

Amendment
to Series A Preferred Share Purchase Agreement

 

Reference
is made to the Series A Preferred Share Purchase Agreement, dated as of January 29, 2014 and between Entera Bio Ltd. (the “Company”)
and Centillion Fund (the “Investor”), as amended on June 18, 2014, January 21, 2015 and November 2015 (as amended,
the “Agreement”). Any capitalized terms used but not defined herein shall have such meaning provided to them
in the Agreement.

 

The
parties hereby agree that notwithstanding anything to the contrary, and in accordance with Section 10.4 of the Agreement, the
terms of the Agreement are hereby amended as follows:

 

		1)	The
                                         last date for the consummation of the second Milestone Event is hereby extended to July
                                         20, 2019 (the “Cut-Off Date”). 

		2)	Notwithstanding
                                         anything to the contrary, it is hereby agreed that effective as of the occurrence of
                                         the second Milestone Event and until the Cut-Off Date, the Investor shall have the option,
                                         at its sole discretion, to invest any or all of the Milestone Investment Amount. For
                                         the avoidance of doubt, such investment shall not be mandatory.

		3)	Schedule
                                         1.2(a) of the Agreement is hereby amended so that the second Milestone Event shall be
                                         deemed to include any transaction pursuant to which the Company’s shares will be
                                         listed for trading on the NASDAQ.

 

Except
to the extent amended hereby, all of the definitions, terms, provisions and conditions set forth in the Agreement, as amended,
are hereby ratified and confirmed and shall remain in full force and effect. The Agreement, as amended, and this Amendment shall
be read and construed together as a single agreement.

 

[Signature
page to follow]

 

 

     

     

    

 

In witness
whereof, the parties have caused this Amendment to be executed and delivered by their duly authorized representatives, all as
of the date first written above.

 

 

COMPANY:

 

ENTERA BIO LTD.

 

	By:	/s/ Phillip Schwartz	 
	 	 	 
	Name:   	Phillip Schwartz	 
	 	 	 
	Title:	CEO	 

 

 

 

INVESTOR

 

CENTILLION FUND

 

	By:	/s/ Sean Ellis	 
	 	 	 
	Name:   	 Sean Ellis	 
	 	 	 
	Title:	C/O	 

 

[Signature
Page / Amendment to Series A Preferred Share Purchase Agreement]Exhibit
10.9

 

 

SERIES
B PREFERRED SHARE PURCHASE AGREEMENT

 

THIS
SERIES B PREFERRED SHARE Purchase Agreement (the “Agreement”)
is made as of the 4 day of October, 2017 (the “Effective Date”), by and between Entera Bio Ltd., an Israeli
company (the "Company") and the Investors whose names are listed in Exhibit A hereto (each, an “Investor”
and collectively, the “Investors”).

 

WHEREAS,
the Company wish to raise capital from the Investors (the “Financing”) by means of issuance of Series B Preferred
Shares of the Company, with par value of NIS 0.01 per share (the “Preferred B Shares”), at a price per
share of US $908.78 for each Preferred B Share (the “PPS”), for an aggregate purchase price of at least
US $10,000,000 (the “Required Investment Amount”) and up to a maximum investment amount of US $23,500,000 (the “Maximum
Investment Amount”) and up to a maximum of issuance of 25,858 Preferred B Shares (the “Maximum Purchased
Shares”);

 

WHEREAS,
the Investors desire to invest in the Company pursuant to the terms and conditions more fully set forth in this Agreement.

 

NOW,
THEREFORE, in consideration of the mutual promises and covenants set forth herein, the parties hereby agree as follows.

 

		1.	The
                                         Transactions

 

1.1.                     
Issuance and Purchase of the Preferred B Shares at the Initial Closing. Subject to the terms and conditions hereof
(including without limitation, the receipt of at least the Required Investment Amount from the Initial Investors(as hereafter
defined)), the Company shall issue and sell to Investors purchasing Preferred B Shares at the Initial Closing (the “Initial
Investors”), and each of the Initial Investors shall, severally and not jointly, purchase from the Company (each in the
amount set out in the Purchase Price column set out opposite each Initial Investor’s name on Exhibit A, as may be
amended at each of the Deferred Closing (as defined below)) at the Initial Closing (as defined below), the respective number of
Preferred B Shares as set forth opposite to each Initial Investor’s name in Exhibit A in consideration for a price
per each share equal to the PPS. The aggregate investment amount to be invested by all Initial Investors at the Initial Closing
shall be deemed as the “Initial Purchase Price”, and aggregate number of Preferred B Shares to be purchased
by all Initial Investors shall be deemed as the “Initial Purchased Shares”.

 

1.2.                     
Conversion of the 2016 Convertible Loans at the Initial Closing. Simultaneously with the Initial Closing, the Loan
Obligations (as such term is defined in the 2016 CLA) extended to the Company pursuant to those certain Convertible Loan Agreements
dated as of June 14, 2016 by the Lenders listed therein (the “2016 CLA”), shall be automatically converted
into such number of Series B-1 Preferred Shares of the Company, par value of NIS 0.01 per share (the “Preferred B-1 Shares”,
and together with the Preferred B Shares, the “Class B Preferred Shares”), according to the terms and
conditions of the 2016 CLA, and subject to tax withholding as required according to applicable tax laws.

 

1.3.                     
Issuance and Purchase of Shares at Deferred Closing(s). Until October 25, 2017, the Company may, at its sole discretion,
effect one or more deferred closings (each, a “Deferred Closing”, and together with Initial Closing, the “Closing(s)”),
on the same terms and conditions as those contained in this Agreement, and issue and allot at such Deferred Closings additional
Preferred B Shares (in an amount not to exceed the Maximum Purchased Shares minus the Initial Purchased Shares) (the “Deferred
Closing Shares”) at the PPS, to one or more investors (including to the Lenders of the 2016 CLA according to its terms)
(the “Additional Investors”, as set forth in Exhibit A, as amended at the Deferred Closings, and together
with the Initial Investors, the “Investors”). The aggregate investment amount to be invested by all Deferred
Investors at the Deferred Closings shall be deemed as the “Deferred Purchase Price” (together with the Initial Purchase
Price, the “Purchase Price”), and the aggregate number of 

 

     

    2 

    

Preferred
B Shares to be purchased by all Investors at the Deferred Closings shall be deemed as the “Deferred Purchased Shares”
(together with the Initial Purchased Shares, the “Purchased Shares”). For the avoidance of doubt the Purchase
Price shall not exceed the Maximum Investment Amount. Each Deferred Investor shall be required to execute the signature page of
this Agreement. Exhibit A will be updated to reflect each Deferred Closing.

 

		2.	Initial
                                         Closing 

 

2.1.                     
Initial Closing. The transaction set forth in Sections 1.1 and 1.2 above shall take place at such date, time and
place as the Company and the Initial Investors holding the majority of the Initial Purchase Price, including the affirmative consent
of D.N.A Biomedical Solutions Ltd. (the “Majority Investors”) shall mutually agree (the “Initial Closing”,
and the “Initial Closing Date”).

 

2.2.                     
Transactions at the Initial Closing. At the Initial Closing, the following transactions shall occur, which transactions
shall be deemed to take place simultaneously and no transaction shall be deemed to have been completed or any document delivered
until all such transactions have been completed and all required documents delivered:

 

2.2.1.     
The Company shall issue the Initial Purchased Shares to the Initial Investors, as provided in Section 1.1 hereof.

 

2.2.2.     
The Company shall deliver to the Initial Investors the following documents or cause the following actions to be completed:

 

2.2.2.1.                    
Copies of minutes of the Company's shareholders, in the form attached hereto as Schedule 2.2.2.1(A), by which, among
other things, (i) the share capital of the Company shall have been modified to create the new series of Class B Preferred Shares
and the Existing Articles have been replaced with the Amended and Restated Articles of Association attached hereto as Schedule
2.2.2.1(B) (the “Amended Articles”), (ii) the shareholders of the Company shall have waived any preemptive
in connection with the issuance of the Purchased Shares, and (iii) this Agreement and all other Transaction Documents (as defined
below), shall have been approved;

 

2.2.2.2.                    
Copies of minutes of the resolutions of the Board of Directors of the Company (the “Board”), in the
form attached hereto as Schedule 2.2.2.2, by which the Company's Board (i) approves the issuance and the sale of the Initial
Purchased Shares to the Initial Investors, (ii) recommends to the Company's shareholders to adopt the Amended Articles, and (iii)
approves this Agreement and all other Transaction Documents;

 

2.2.2.3.                    
Validly executed share certificates representing the Initial Purchased Shares, issued in the names of the Initial Investors,
in the form attached hereto as Schedules  2.2.2.3;

 

2.2.2.4.                    
The Company shall register the allotment of the Initial Purchased Shares to the Initial Investors in the Shareholders Register
of the Company.

 

2.2.3.    
The Initial Investors shall, severally and not jointly, cause the transfer to the Company of the applicable portions of
the Initial Purchase Price in consideration of the Initial Purchased Shares, by wire transfer to the Company’s bank account
as designated by the Company in writing prior to the Initial Closing.

 

2.2.4.    
The Company and the Initial Investors shall execute and deliver the Investors’ Rights Agreement in the form attached
hereto as Schedule 2.2.4 (the “IRA”).

 

     

    3 

    

2.2.5.    
Each Investor, which is deemed to be an interested party as determined according to the Israeli Securities law shall execute
and deliver to the company undertakings to the National Technological Innovation Authority (formerly the Israeli Office of the
Chief Scientist - hereinafter referred to as the "OCS"), as required by the provisions of the Encouragement of
Research, Development and Technological Innovation in the Industry Law 5744-1984 in the form attached hereto as Schedule 2.2.5
(the "OCS Undertakings").

 

		3.	Deferred
                                         Closing 

 

3.1.                     
Initial Closing. The transaction set forth in Section 1.3 above shall take place at such date, time and place as
the Company shall determine at its sole discretion, in the form of one or more installments, provided that the last Deferred Closing
shall occur no later than October 25, 2017 (each such Deferred Closing shall occur on a “Deferred Closing Date”).

 

3.2.                     
Transactions at the Deferred Closing. At the Deferred Closing, the following transactions shall occur, which transactions
shall be deemed to take place simultaneously and no transaction shall be deemed to have been completed or any document delivered
until all such transactions have been completed and all required documents delivered:

 

3.2.1.     
Each Deferred Investor shall execute the signature page of this Agreement.

 

3.2.2.     
The Company shall issue the Deferred Purchased Shares to the Deferred Investors, as provided in Section 1.3 hereof.

 

3.2.3.     
The Company shall deliver to the Deferred Investors validly executed share certificates representing the Deferred Purchased
Shares, issued in the names of the Deferred Investors, and shall register the allotment of the Deferred Purchased Shares to the
Deferred Investors in the Shareholders Register of the Company.

 

3.2.4.     
The Deferred Investors shall, severally and not jointly, cause the transfer to the Company of the applicable portions of
the Deferred Purchase Price in consideration of the Deferred Purchased Shares, by wire transfer to the Company’s bank account
as designated by the Company in writing prior to the Deferred Closing.

 

3.2.5.     
The Deferred Investors shall execute and deliver the IRA.

 

3.2.6.     
Each Deferred Investor, which is deemed to be an interested party as determined according to the Israeli Securities law
shall execute and deliver to the company the OCS Undertaking.

 

		4.	Representations
                                         and Warranties of the Company

 

The
Company hereby represents and warrants to the Investors, that except as set forth on the Disclosure Schedule attached as Exhibit
4 to this Agreement (the “Original Disclosure Schedule”), which exceptions shall be deemed to be part of the
of the representations and warranties made hereunder (and which may be amended from time to time), the each of the representations
and warranties contained in this Section 4 is true in all material respects as of the date hereof, the Initial Closing Date and
the Deferred Closing Dates (or, if a representation or warranty is made as of a specified date, as of such date), provided that
the Company may amend and update the Disclosure Schedule (the “Amended Disclosure Schedule”, and together with
the Original Disclosure Schedule, the “Disclosure Schedule”) and provide the Investors with the Amended Disclosure
Schedule prior to each Deferred Closing (for avoidance of doubt, each Amended Disclosure Schedule shall be deemed as Disclosure
Schedule for all intents and purposes under this Agreement), and acknowledges that the Investors are entering into this Agreement
in reliance thereon, as follows.

 

     

    4 

    

4.1.                     
Organization. The Company is duly organized and validly existing under the laws of the State of Israel, and has
full corporate power and authority to own, lease and operate its properties and assets and to conduct its business as now being
conducted. The Company has all requisite power and authority to execute and deliver the Transaction Documents and to consummate
the transactions contemplated hereby and thereby. The Articles of Association of the Company as in effect immediately prior to
the Initial Closing (until the adoption of the Amended Articles) are attached hereto as Schedule 4.1 (the “Existing
Articles”).

 

4.2.                     
Subsidiaries. The Company has no subsidiaries and does not otherwise own or control, directly or indirectly,
any equity interest in any corporation, association or business entity. 

 

4.3.                     
Capitalization. The capitalization table of the Company attached hereto as Schedule 4.3 (the “Capitalization
Table”), sets forth the number and class of shares held by each shareholder of the Company, the total number of reserved
and granted/promised options, warrants to purchase the share capital of the Company immediately prior to and immediately following
the Initial Closing. The post-closing Capitalization Table as of the Effective Date reflects an Initial Purchase Price of US $10,000,000,
provided however that such Capitalization Table shall be updated upon the Initial Closing to reflect the actual Initial Purchase
Price, which in any case shall be at least US $10,000,000. All issued and outstanding share capital of the Company has been duly
authorized, and is validly issued and outstanding and fully paid and non-assessable. The Purchased Shares, when issued, sold and
delivered in accordance with this Agreement, will be duly authorized, validly issued, fully paid, non-assessable, free of any
preemptive rights, will have the rights, preferences, privileges, and restrictions set forth in the Amended Articles, and duly
registered in the name of each Investor in the Company's register of shareholders. 

 

4.4.                     
Authorization; Approvals. All corporate action on the part of the Company necessary for the authorization, execution,
delivery, and performance of all of the Company's obligations under this Agreement and any and all other agreements executed or
documents delivered in connection herewith or therewith (collectively, the “Transaction Documents”), and for
the authorization, issuance, and sale of the Purchased Shares being sold under this Agreement has been (or will be) taken prior
to the Initial Closing. The Transaction Documents, when executed and delivered by or on behalf of the Company shall constitute
the valid and legally binding obligations of the Company and legally enforceable against the Company in accordance with their
respective terms. Other than the execution of undertakings to the OCS by certain Investors, if required by law, no consent, approval,
order, license, permit, action by, or authorization of or designation, declaration, or filing with any governmental authority
on the part of the Company is required that has not been, or will not have been, obtained by the Company prior to the Initial
Closing in connection with the valid execution, delivery and performance of the Transaction Documents or the offer, sale, or issuance
of the Preferred Series B Shares other than filings with the Israeli Registrar of Companies to be effected following the Initial
Closing.

 

4.5.                     
No Breach. Neither the execution and delivery of any of the Transaction Documents nor compliance by the Company
with the terms and provisions thereof, will conflict with, or result in a breach or violation of, any of the terms, conditions
and provisions of: (i) the Existing Articles, (ii) any judgment, order, injunction, decree, or ruling of any court or
governmental authority, domestic or foreign, (iii) any material agreement to which the Company is a party or to which it
is subject, or (iv) applicable law. 

 

4.6.                     
Litigation. To the knowledge of the Company, no action, suit, litigation, proceeding or audit, nor an examination
of any governmental entity of which the Company was notified, nor any governmental inquiry or investigation is pending or, to
the knowledge of the Company, threatened against the Company, before any court, arbitration board or tribunal or administrative
or other governmental agency. 

 

4.7.                     
Government Funding. Other than a grant of approximately US $450,000 from the OCS, 

 

     

    5 

    

the
Company has not received any grant or other support or benefits (including, without limitation, tax benefits) from any Israeli
or foreign government entity or agency.

 

4.8.                     
Limitation of Liability. Each representation made herein by the Company is deemed to be made on the date of the
Initial Closing and shall survive and remain in full force and effect after the Initial Closing for a period of one (1) year from
the Initial Closing Date. The Company’s liabilities towards each Investor in connection with the Company’s representations
and warranties shall be limited to the amount invested by such Investor hereunder. Notwithstanding the above, no claim or claims
under this Section 1.1 shall be brought, unless the aggregate amount of such claim(s) shall exceed US $100,000, provided that
in case of a claim or claims in excess of the aforesaid threshold, the claim will apply for the entire amount (i.e., from the
first dollar).

 

4.9.                     
Additional Representations and Warranties. The Company hereby represents and warrants to the Investors the additional
representations set forth in Exhibit 4.9 to this Agreement.

 

		5.	Representations
                                         and Warranties of the Investors 

 

Each Investor
hereby represents and warrants, severally and not jointly, as of the Initial Closing Date, to the Company as follows:

 

5.1.                     
Experience; Speculative Nature of Investment. The Investor has experience in evaluating and investing in private
placement transactions of securities in companies similar to the Company so that it is capable of evaluating the merits and risks
of its investment in the Company and has the capacity to protect its own interests. Such Investor further acknowledges that this
Agreement and the issuance of the Purchased Shares hereunder do not constitute a promise or guaranty by the Company or its shareholders
or directors as to the financial or commercial success of the Company or the future value of its shares.

 

5.2.                     
Investment.  Such Investor is acquiring the Purchased Shares for investment for its own account, not as a nominee
or agent, and not with the view to, or for resale in connection with, any distribution thereof, and such Investor has no present
intention of selling, granting any participation in, or otherwise distributing the same, in each case, unless otherwise agreed
in writing prior to or on the Effective Date by the Company and the Investor.

 

5.3.                     
Enforceability.  The Transaction Documents, when executed and delivered by such Investor, will constitute valid
and legally binding obligations of the Investor, enforceable in accordance with their terms, subject to laws of general application
relating to bankruptcy, insolvency and the relief of debtors and rules of law governing specific performance, injunctive relief
or other equitable remedies.

 

5.4.                     
Authorization. The execution, delivery and performance of the obligations of such Investor hereunder have been duly
authorized by all necessary corporate action. 

 

5.5.                     
Due Diligence. The Investor has had an opportunity to ask the Company questions regarding the business, properties,
prospects and financial condition of the Company. The Investor acknowledges that any projections provided (if any) by the Company
are uncertain in nature, and that some or all of the assumptions underlying such projections may not materialize or will vary
significantly from actual results 

 

5.6.                     
Accredited Investor. The Investor is an “accredited investor” within the meaning of Rule 501 under the
Securities Act of 1933, as amended, and the rules and regulations promulgated thereunder (the “Securities Act”).

 

5.7.                     
Restricted Securities. The Purchased Shares have not been and will not be registered under the Securities Act or
any state securities laws and, therefore, cannot be resold unless they are 

 

     

    6 

    

registered
under the Securities Act and applicable state securities laws or unless an exemption from such registration requirements is available.
Each Investor is aware that, except as set forth in the IRA, the Company is under no obligation to effect any such registration
or to file for or comply with any exemption from registration. The sale and issuance of the Purchased Shares have not been registered
under the Securities Act by reason of a specific exemption from registration which depends upon, among other things, the accuracy
of the Investor’s representations as expressed herein.

 

5.8.                     
The Investor understands that the Purchased Shares and any securities issued in respect of or exchange for the Purchased
Shares, may be notated with one or all of the following legends: 

 

“THE
SHARES REPRESENTED HEREBY HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AND HAVE BEEN ACQUIRED FOR INVESTMENT AND
NOT WITH A VIEW TO, OR IN CONNECTION WITH, THE SALE OR DISTRIBUTION THEREOF. NO SUCH TRANSFER MAY BE EFFECTED WITHOUT AN EFFECTIVE
REGISTRATION STATEMENT RELATED THERETO OR AN OPINION OF COUNSEL IN A FORM SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATION IS
NOT REQUIRED UNDER THE SECURITIES ACT OF 1933.”

 

(a)                    
Any legend set forth in, or required by, the other Transaction Agreements.

 

(b)                   
Any legend required by the securities laws of any state to the extent such laws are applicable to the Shares represented
by the certificate, instrument, or book entry so legended.

 

		6.	Conditions
                                         of Closing of the Investors

 

The
obligations of the Investors to transfer the applicable Purchase Price at each of the Initial and Deferred Closings, as applicable,
are subject to the fulfillment at or before the applicable Closings of the following conditions precedent, any one or more of
which may be waived in whole or in part by the Investors, which waiver shall be at the sole discretion of the Majority Investors
in the event of the Initial Closing, or the investors holding the majority of the Purchase Price of each Deferred Closing, as
applicable:

 

6.1.                     
The representations and warranties made by the Company in this Agreement shall have been true and correct when made, and
shall be true and correct as of the applicable Closing as if made on the date of the applicable Closing.

 

6.2.                     
All covenants, agreements, and conditions (including all corporate proceedings) contained in this Agreement to be performed
or complied with by the Company prior to the applicable Closing shall have been performed or complied with by the Company prior
to or at the applicable Closing.

 

6.3.                     
The Company shall have secured all permits, consents and authorizations that shall be necessary or required lawfully to
consummate this Agreement, if any, and to issue the applicable Purchased Shares at the applicable Closing.

 

6.4.                     
All of the documents to be delivered by the Company pursuant to Sections 2.2 or 3.2, as applicable, shall have been
delivered to the Investors. 

 

		7.	Conditions
                                         of Closing of the Company

 

The
Company’s obligations at each of the Initial and Deferred Closings shall be subject to:

 

7.1.                     
The Investors causing the transfer to the Company of the applicable Purchase Price for the applicable Purchased Shares.

 

     

    7 

    

7.2.                     
The representations and warranties made by the Investors herein shall have been true and correct in all respects when made
and shall be true and correct on the date of the applicable Closing.

 

7.3.                     
All covenants, agreements and conditions contained in this Agreement to be performed, or complied with, by the Investors
prior to the applicable Closing, shall have been performed or complied with by the Investors.

 

7.4.                     
All of the documents to be delivered by the Investors pursuant to Sections 2.2 or 3.2, as applicable, shall have
been delivered to the Company. 

 

		8.	Conditions
                                         of Initial Closing of the Company and the Investors; Termination. The Investors'
                                         and the Company’s obligations at the Initial Closing shall be subject to the receipt
                                         by the Company of an aggregate Initial Purchase Price from the Investors in an amount
                                         of at least US $10,000,000. Notwithstanding anything to the contrary in this Agreement,
                                         if the closing condition set forth in this Section 8 is not met by October 25, 2017 (the
                                         “Cut-off Date”), then this Agreement shall effective as of the Cut-off
                                         Date immediately and automatically terminate and be of no force and effect, without requiring
                                         any further actions on behalf of the either of the parties to this Agreement, and neither
                                         of the parties to this Agreement shall have any further obligations or claims to any
                                         of the other parties to this Agreement following the termination of this Agreement according
                                         to this Section 8.

 

		9.	Miscellaneous

 

9.1.                     
Further Assurances. From and after the date of this Agreement, upon the request of the Company, the Company and
the Investors shall execute and deliver such instruments, documents and other writings as may be reasonably necessary or desirable
to confirm and carry out and to effectuate fully the intent and purposes of this Agreement.

 

9.2.                     
No Public Disclosure. Other than with respect to publishing a prospectus by the Company in connection with a future
initial public offering of its securities, with respect to the Lenders pursuant to the Convertible Loans, or with respect to potential
future investors and/or lenders to the Company, no party hereto shall publicly announce or disclose the existence of this Agreement
or its terms and conditions, or advertise or release any publicity regarding this Agreement or the transactions contemplated hereunder
(the “Transaction Terms”), without the prior written consent of the Company and the Majority Investors, except
that (i) the parties hereto may disclose to third parties any information regarding the Transaction Terms which is known or becomes
known to the public in general (other than as a result of a breach of this Section 9.2 by the disclosing party), and (ii)
the parties hereto may disclose Transaction Terms to the extent legally required in order to comply with any court order, applicable
law or order from regulatory authorities.

 

9.3.                     
Governing Law; Jurisdiction. This Agreement shall be governed by and construed in accordance with the laws of the
State of Israel, excluding that body of law pertaining to conflict of law. The competent courts in Tel Aviv-Jaffa district shall
have exclusive jurisdiction over any dispute or claim arising in connection with or as a result of this Agreement; provided
however that notwithstanding the foregoing, only with respect to any individual Investor who is a resident of the
United States of America or Canada or any Investor who is a legal entity incorporated in the United States of America or
Canada: (i) each of the Company and any such Investor hereby irrevocably submits to the exclusive jurisdiction of the state and
federal courts sitting in The City of New York, Borough of Manhattan, for the adjudication of any dispute hereunder, and hereby
irrevocably waives, and agrees not to assert in any suit, action or proceeding, any claim that it is not personally subject to
the jurisdiction of any such court, that such suit, action or proceeding is brought in an inconvenient forum or that the venue
of such suit, action or proceeding is improper; (ii) the Company and such Investor hereby irrevocably waives personal service
of process and consents to process being served in any such suit, action or proceeding by mailing a copy thereof to the Company
at the address set forth in this Agreement and agrees that such service 

 

     

    8 

    

shall
constitute good and sufficient service of process and notice thereof; (iii) nothing contained herein shall be deemed to limit
in any way any right to serve process in any manner permitted by law; and (iv) the prevailing party, as determined by such court
shall be entitled to collect any costs, disbursements and reasonable attorney’s fees from the other party.

 

9.4.                     
Successors and Assigns; Assignment. Except as otherwise expressly provided herein, the provisions hereof shall inure
to the benefit of, and be binding upon, the successors, assigns, heirs, executors, and administrators of the parties hereto. None
of the rights, privileges, or obligations set forth in, arising under, or created by this Agreement may be assigned or transferred
without the prior consent in writing of each party to this Agreement, with the exception of the transfer of the applicable Purchased
Shares by an Investor according to the terms and conditions of the Amended Articles.

 

9.5.                     
Entire Agreement; Amendment and Waiver. This Agreement and the Schedules attached hereto constitute the full and
entire understanding and agreement between the parties with regard to the subject matters hereof and thereof. Any term of this
Agreement may be amended and the observance of any term hereof may be waived (either prospectively or retroactively and either
generally or in a particular instance) only with the written consent of the Company and the Investors holding the majority of
the Purchase Price, including the affirmative consent of D.N.A Biomedical Solutions Ltd.

 

9.6.                     
Notices, etc. All notices and other communications required or permitted hereunder to be given to a party to this
Agreement shall be in writing and shall be faxed, or mailed, postage prepaid, or otherwise delivered by electronic mail, hand
or by guaranteed courier, addressed to such party’s address as set forth below or at such other address as the party shall
have furnished to each other party in writing in accordance with this provision:

 

	if to the Investors:

        
	The address set forth
        in the signature page.

        

	 	 
	 	 
	if to the Company:	Entera Bio Ltd.

        Jerusalem Bio Park

        

        PO Box 12117

        Jerusalem
91220

        

        Tel: +972-54-535-2683

        

        Attn: Dr.
        Phillip Schwartz

        

        E-mail: phillip@enterabio.com

         

        with a copy (which shall
        not constitute notice) to:

        

        Herzog Fox
        & Neeman,

        

        4 Weizmann
        Street,

        

        Tel-Aviv 6423904,
        Israel

        

        Attn: Yair
        Geva, Adv.; Tomer Farkash, Adv.

        

        Fax no. +972-3-6966464

        

        Email: gevay@hfn.co.il,
        farkasht@hfn.co.il

        

 

or such
other address with respect to a party as such party shall notify each other party in writing as above provided. Any notice sent
in accordance with this Section 9.6 shall be effective (i) if mailed, two (2) business days after mailing, (ii) if sent
by guaranteed courier, the second day following pick-up by the guaranteed courier, and (iii) if faxed, upon transmission and electronic
confirmation of receipt or (if transmitted and received on a non-business day) on the first business day following transmission
and electronic confirmation of receipt. Notices sent by electronic mail shall be deemed received upon confirmation of receipt
of such electronic mail message.

 

     

    9 

    

9.7.                   
Delays or Omissions. No delay or omission to exercise any right, power, or remedy accruing to any party upon any
breach or default under this Agreement shall be deemed a waiver of any other breach or default theretofore or thereafter occurring.
Any waiver, permit, consent, or approval of any kind or character on the part of any party of any breach or default under this
Agreement, or any waiver on the part of any party of any provisions or conditions of this Agreement, must be in writing and shall
be effective only to the extent specifically set forth in such writing. All remedies, either under this Agreement or by law or
otherwise afforded to any of the parties, shall be cumulative and not alternative.

 

9.8.                   
Severability. If any provision of this Agreement is held by a court of competent jurisdiction to be unenforceable
under applicable law, then such provision shall be excluded from this Agreement and the remainder of this Agreement shall be interpreted
as if such provision were so excluded and shall be enforceable in accordance with its terms; provided, however,
that in such event this Agreement shall be interpreted so as to give effect, to the greatest extent consistent with and permitted
by applicable law, to the meaning and intention of the excluded provision as determined by such court of competent jurisdiction.

 

9.9.                   
Counterparts. This Agreement may be executed in any number of counterparts, each of which shall be deemed an original
and enforceable against the parties actually executing such counterpart, and all of which together shall constitute one and the
same instrument.

 

9.10.                 
Expenses. Each Party shall be responsible and shall bear its own respective costs and expenses related to this Agreement
and the performance of its obligations hereunder, including all of its respective tax consequences.

 

9.11.                 
Headings. Article, Section and subsection headings in this Agreement are included herein for convenience of reference
only and shall not constitute a part of this Agreement for any other purpose.

 

[Remainder
of page intentionally left blank.]

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

     

    10 

    

IN
WITNESS WHEREOF the parties have signed this Series B Preferred Share Purchase Agreement as of the date first hereinabove
set forth.

 

The Company:  

 

ENTERA BIO LTD.

 

	By:	/s/ Phillip Schwartz	 
	Name:   	Phillip Schwartz	 
	Title:	CEO	 

 

 

 

  

 

 

 

[Signature
Page to Entera Bio Ltd. Series B Preferred SPA]

 

 

 

 

 

 

 

 

 

 

     

    11 

    

The Investor:

 

	By:	 	 
	Name:   	 	 
	Title:	 	 
	Address:     	 	 

 

	Purchase Price: US$     	 	 

 

 

 

 

 

 

 

 

 

[Signature
Page to Entera Bio Ltd. Series B Preferred SPA]

 

 

 

 

 

 

 

 

 

 

 

  

 

     

    12 

    

Exhibit
A

 

Investors

 

Initial
Closing – October 4, 2017

 

	Name
    of Investor	Address	Purchase
    Price at the Initial Closing (in US$)	Number
    of Preferred B Shares to be purchased at the Initial Closing 
	D.N.A. Biomedical Solutions Ltd.	[Intentionally omitted]	6,000,000.00
    	6,602
	Robert
    Stricker 	 	99,965.80
    	110
	Jean
    Marc Bara	 	99,965.80
    	110
	Gary
    S. Gladstein 2009 Revocable Trust 	 	125,411.60
    	138
	Ruth
    T. Benanav Revocable Trust)	 	124,502.86
    	137
	Efrat
    Investments	 	49,982.90
    	55
	FirstFire
    Global Opportunities Fund LLC	 	49,982.90
    	55
	Thomas
    J. Holevas	 	49,982.90
    	55
	Harold
    and Nancy Jacob 	 	24,537.06
    	27
	Gil
    Barel 	 	49,982.90
    	55
	Oren
    Elbaz 	 	29,989.74
    	33
	Avi
    Domoshevizki	 	49,982.90
    	55
	Piada
    Investment 	 	99,965.80
    	110
	Rosalind
    Capital Partners L.P	 	567,078.72
    	624
	Rosalind
    Master Fund L.P.	 	232,647.68
    	256
	Gerald
    Lieberman 	[Intentionally omitted]	99,965.80
    	110
	Centillion
    Fund	[Intentionally omitted]	324,434.46
    	357
	Gal
    Gordon 	 	49,982.90
    	55
	Revach
    Fund LP Investment	 	12,726.00
    	14
	Phillip
    Schwartz	 	5,453.00
    	6
	Northlea
    Partners LLLP	[Intentionally omitted]	24,537.06
    	27
	Republic
    Construction Corporation	[Intentionally omitted]	25,445.84
    	28

 

 

     

    13 

    

	Name
    of Investor	Address	Purchase
    Price at the Initial Closing (in US$)	Number
    of Preferred B Shares to be purchased at the Initial Closing 
	Joe
    N. & Jamie W. Behrendt Revocable Trust dtd 10/30/96	[Intentionally
omitted]	24,537.06
    	27
	Gibralt
    US, Inc.	[Intentionally
omitted]	249,914.50
    	275
	Bozarth
    LLC	[Intentionally
omitted]	49,982.90
    	55
	Richard
    A Brown Trust	[Intentionally
omitted]	127,229.20
    	140
	Alexander
    J. Brown Trust	[Intentionally
omitted]	127,229.20
    	140
	Robert
    G. Curtin	[Intentionally
omitted]	27,263.40
    	30
	Robert
    G. Curtin 401k	[Intentionally
omitted]	299,897.40
    	330
	Rob
    DeSantis	[Intentionally
omitted]	199,931.60
    	220
	Stephen
    A. DiChiara	[Intentionally
omitted]	29,989.74
    	33
	James
    L. Dritz	[Intentionally
omitted]	25,445.84
    	28
	Norm
    Dumbroff	[Intentionally
omitted]	19,993.16
    	22
	Robert
    D. Frankel	[Intentionally
omitted]	14,540.48
    	16
	Charles
    Freeland	[Intentionally
omitted]	9,996.58
    	11
	John
    P. Funkey Revocable Trust dtd 2/26/90	[Intentionally
omitted]	19,993.16
    	22
	John
    O. Gallant	[Intentionally
omitted]	39,986.32
    	44
	Albert
    Gentile & Hiedi Gentile	[Intentionally
omitted]	29,989.74
    	33
	Richard
    Gostanian	[Intentionally
omitted]	49,982.90
    	55
	Gubbay
    Investments LLC	[Intentionally
omitted]	34,533.64
    	38
	Joel
    L. Hochman Revocable Trust UAD 12/8/1994	[Intentionally
omitted]	49,982.90
    	55
	Edward
    O'Connell	[Intentionally
omitted]	19,993.16
    	22

 

 

     

    14 

    

	Name
    of Investor	Address	Purchase
    Price at the Initial Closing (in US$)	Number
    of Preferred B Shares to be purchased at the Initial Closing 
	Michael
    J. Pierce	[Intentionally
omitted]	249,914.50
    	275
	Casimir
    S. Skrzypczak	[Intentionally
omitted]	29,989.74
    	33
	David
    & Susan Stollwerk	[Intentionally
omitted]	24,537.06
    	27
	Howard
    Stringer	[Intentionally
omitted]	24,537.06
    	27
	Clayton
    Struve	[Intentionally
omitted]	49,982.90
    	55
	Raphael
    Tshibangu	[Intentionally
omitted]	25,445.84
    	28
	The
    Elizabeth M. Walenczyk 2011 Revocable Trust	[Intentionally
omitted]	99,965.80
    	110
	Michael
    Zimmerman	[Intentionally
omitted]	18,175.60
    	20

 

 

Deferred
Closing Investors – October 25, 2017

 

	Name of Investor	Address	Purchase
    Price at the Deferred Closing (in US$)	Number
    of Preferred B Shares to be purchased at the Deferred Closing 
	Asaf
    Oren 	 	49,982.90
	55

	Lars
    Bader	[Intentionally
omitted]	500,737.78
	551

	Yisroel
    Brauner & Chana Brauner	[Intentionally
omitted]	50,891.68
	56

	Meryle
    Evans Family Trust	[Intentionally
omitted]	50,891.68
	56

	Andrew
    & Melissa Fisher	[Intentionally
omitted]	50,891.68
	56

	Walter
    G. Gans	[Intentionally
omitted]	18,175.60
	20

	M
    & M Investors (Partnership)	[Intentionally
omitted]	99,965.80
	110

 

 

     

    15 

    

	Name of Investor	Address	Purchase
    Price at the Deferred Closing (in US$)	Number
    of Preferred B Shares to be purchased at the Deferred Closing 
	Clay
    Lebhar	[Intentionally
omitted]	50,891.68
	56

	Clyde
    Smith McGregor & LeAnn Pedersen Pope Revocable Trust U/A/D 10/22/16	[Intentionally
omitted]	908,780.00
	1,000

	Daniel
    Michael 	[Intentionally
omitted]	49,982.90
	55

	Gilbert
    S. Omenn	[Intentionally
omitted]	100,874.58
	111

	David
    M. Rickey Trust dtd 5/8/02	[Intentionally
omitted]	25,445.84
	28

	Dyke
    Rogers	[Intentionally
omitted]	50,891.68
	56

	Sack
    Investment Holdings SAS, LLC	[Intentionally
omitted]	49,982.90
	55

	Sack
    Family Partners, LP	[Intentionally
omitted]	49,982.90
	55

	Whiting
    Holdings, LP 	[Intentionally
omitted]	100,874.58
	111

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