Document:

Exhibit 4.1

 Exhibit 4.1 
 AGREEMENT OF RESIGNATION, APPOINTMENT AND ACCEPTANCE, dated as of October 1, 2006 by and among GSS Holdings II, Inc., a Delaware corporation, as Trust Beneficial Owner (the “Trust Beneficial
Owner”), The Bank of New York, a New York banking corporation (the “Prior Trustee”) and U.S. BANK NATIONAL ASSOCIATION, a national banking association duly organized and existing under the laws of the United States of America
(the “Successor Trustee”). 
 RECITALS: 
 WHEREAS, the Trust Beneficial Owner and the Prior Trustee have previously entered into the Trust Agreements specified in Exhibit A hereto (the “Trust Agreements” and individually, a “Trust
Agreement”) with respect to the Genworth Global Funding Trusts (the “Trusts” and individually a “Trust”) specified therein, pursuant to which Secured Medium-Term Notes (the “Notes”), secured by Funding Agreements
issued by Genworth Life and Annuity Insurance Company (“GLAIC”), have been issued; 
 WHEREAS, Section 8.02 of each
Trust Agreement provides that the Trustee may at any time resign by giving written notice of such resignation to the Trust Beneficial Owner, GLAIC and the applicable Indenture Trustee with such resignation to become effective upon the payment of all
fees and expenses, including indemnity payments, due to the outgoing Trustee and upon acceptance by a successor Trustee of its appointment as a successor Trustee; 
 WHEREAS, Section 8.02 of each Trust Agreement provides that if the Trustee shall resign, the Trust Beneficial Owner shall promptly appoint a successor Trustee meeting the qualifications set forth in
Section 8.01 of each Trust Agreement; 
 WHEREAS, Section 8.03 of each Trust Agreement provides that any successor Trustee
appointed in accordance with such Trust Agreement shall execute, acknowledge and deliver to the Trust Beneficial Owner, the applicable Indenture Trustee and to its predecessor Trustee an instrument accepting such appointment under such Trust
Agreement, and thereupon the resignation of the predecessor Trustee shall become effective and such successor Trustee, without any further act, deed or conveyance, shall become vested with all rights, powers, duties and obligations of the
predecessor Trustee; 
 WHEREAS, the Trust Beneficial Owner desires to appoint the Successor Trustee as Trustee to succeed the Prior
Trustee under each Trust Agreement; and 
 WHEREAS, the Successor Trustee is willing to accept such appointment as Successor Trustee
under each Trust Agreement; 
 NOW, THEREFORE, the Trust Beneficial Owner, the Prior Trustee and the Successor Trustee, for and in
consideration of the premises and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, hereby consent and agree as follows: 

 ARTICLE I 
 THE PRIOR TRUSTEE 
 SECTION 1.01 The Prior Trustee hereby resigns as Trustee under each
Trust Agreement. 
 SECTION 1.02 The Prior Trustee hereby assigns, transfers, delivers and confirms to the Successor Trustee all
rights, powers, duties and obligations of the Prior Trustee under each Trust Agreement. The Prior Trustee shall execute and deliver such further instruments and shall do such other things as the Successor Trustee may reasonably require so as to more
fully and certainly vest and confirm in the Successor Trustee all the rights, powers, duties and obligations hereby assigned, transferred, delivered and confirmed to the Successor Trustee. 
 SECTION 1.03 The Prior Trustee hereby represents and warrants to the Successor Trustee that: 
 (a) There is no action, suit or proceeding pending or, to the best of the knowledge of the Responsible Officers assigned to the Prior Trustee’s corporate trust
department, threatened against the Prior Trustee before any court or any governmental authority arising out of any action or omission by the Prior Trustee under any Trust Agreement. 
 (b) As of the effective date of this Agreement, the Prior Trustee will hold no property under any Trust Agreement. 
 (c)
Pursuant to the Trust Agreements, the Prior Trustee duly executed on behalf of the applicable Trusts, on the Issue Dates set forth in Exhibit A attached hereto, the aggregate principal amount of the Notes of each Trust listed in Exhibit A attached
hereto, all of which Notes are Outstanding as of the effective date hereof. 
 (d) Each person who so executed the Notes listed in Exhibit A was duly
elected, qualified and acting as an officer or authorized signatory of the Prior Trustee and was empowered to execute such Notes on behalf of the Prior Trustee at the respective times of such execution and the signature of each person who so
executed such Notes is such person’s genuine signature. 
 (e) This Agreement has been duly authorized, executed and delivered on behalf of the Prior
Trustee and constitutes its legal, valid and binding obligation. 
 (f) The Trusts have performed or fulfilled prior to the date hereof, each covenant,
agreement, condition, obligation and responsibility under each Indenture. 
 (g) No covenant or condition contained in any Trust Agreement has been waived by
the related Trust or, to the best of the Prior Trustee’s knowledge, by the Holders of the percentage in aggregate principal amount of the Trust Securities required under the related Trust Agreement to effect any such waiver. 
 (h) All conditions precedent relating to the appointment of U.S. Bank National Association as Trustee under each Trust Agreement have been complied with by the related
Trust. 
 SECTION 1.04 After the effective date of this Agreement, the Prior Trustee shall retain continued liability for its acts or
omissions as Trustee under the Trust Agreements prior to such effective date (the “Prior Acts”). The Prior Trustee hereby agrees to indemnify and hold harmless the Successor Trustee for any and all claims, liabilities, costs and expenses,
including reasonable attorney’s fees, incurred or suffered by the Successor Trustee as the result of any Prior Acts. 

 SECTION 1.05 With respect to each Trust, the Prior Trustee hereby agrees to transfer the following
items to the Successor Trustee on or before or as soon as practicable after the effective date of this Agreement: 
 (a) PDF files containing
copies of original executed Trust Agreements and all amendments thereto, the related closing transcripts and all transaction documents; and 
 (b) such other documentation in the possession of the Prior Trustee as the Successor Trustee may reasonably require in order to accomplish the transfer of trusteeships. 
 SECTION 1.06 The Prior Trustee acknowledges that no amounts are owing to it as Prior Trustee from the trust assets of the Trusts. 
 ARTICLE II 
 THE TRUST BENEFICIAL
OWNER 
 SECTION 2.01 The Trust Beneficial Owner hereby accepts the resignation of the Prior Trustee as Trustee under each
Trust Agreement. 
 SECTION 2.02 The Trust Beneficial Owner hereby represents that all conditions relating to the appointment of U.S.
BANK NATIONAL ASSOCIATION as Successor Trustee under each Trust Agreement have been complied with, and the Trust Beneficial Owner hereby appoints the Successor Trustee as Trustee under each Trust Agreement with like effect as if originally named as
Trustee therein. 
 SECTION 2.03 The Trust Beneficial Owner hereby represents and warrants to the Prior Trustee and the Successor
Trustee that: 
  

	(a)	Each Trust Agreement was validly and lawfully executed and delivered by the Trust Beneficial Owner. 

 (b) There is no action, suit or proceeding pending or, to the best of the Trust Beneficial Owner’s knowledge, threatened against any Trust before any court or any governmental authority arising out of any action
or omission by such Trust or the Trust Beneficial Owner under the related Trust Agreement. 
 (e) This Agreement has been duly authorized, executed and
delivered by the Trust Beneficial Owner and constitutes its legal, valid and binding obligation. 
 SECTION 2.04 GLAIC, by
acknowledging this Agreement, confirms to the Prior Trustee that all obligations owing to the Prior Trustee under its Expense and Indemnity Agreement with GLAIC, which by their terms survive the termination of such Agreement, shall survive.

 ARTICLE III 
 THE SUCCESSOR TRUSTEE 
 SECTION 3.01 The Successor Trustee hereby represents and
warrants to the Prior Trustee, to each Indenture Trustee and to GLAIC that the Successor Trustee is qualified to act as a Trustee under each Trust Agreement and is eligible to be the Trustee pursuant to Section 8.01 of each Trust Agreement.

 SECTION 3.02 The Successor Trustee hereby accepts its appointment as Successor Trustee under each Trust Agreement and accepts the
rights, powers, duties and obligations of the Prior Trustee under each Trust Agreement, upon the terms and conditions set forth therein, with like effect as if originally named as Trustee therein. 
 ARTICLE IV 
 MISCELLANEOUS

 SECTION 4.01 This Agreement and the resignation, appointment and acceptance effected hereby shall be effective at 12:01 AM
on October 1, 2006. 
 SECTION 4.02 This Agreement shall be governed by and construed in accordance with the laws of the State of
Illinois, without regard to the conflicts of laws principles thereof. 
 SECTION 4.03 This Agreement may be executed in any number of
counterparts each of which shall be an original, but such counterparts shall together constitute but one and the same instrument. 
 SECTION 4.04 This Agreement shall be binding upon and inure to the benefit of the Prior Trustee, the Successor Trustee, the Trusts and their respective successors and assigns. 
 SECTION 4.05 In the event any provision of this Agreement shall be held invalid or unenforceable by any court of competent jurisdiction, such
holding shall not invalidate or render unenforceable any other provision hereof. 
 SECTION 4.06 GLAIC agrees to enter into an Expense
and Indemnity Agreement with the Successor Trustee, in form and substance mutually acceptable to them, providing for the fees, expenses and indemnities of the Successor Trustee, on or before or as soon as practicable after the effective date of this
Agreement. 
 SECTION 4.07 To help the government fight the funding of terrorism and money laundering activities, Federal law requires
all financial institutions to obtain, verify and record information that identifies each person who opens an account. Accordingly, the Successor Trustee may from time to time request that the Trusts provide to the Successor Trustee financial
statements, licenses, identification, documentation verifying their formation and existence as a legal entity and authorization documents from individuals claiming authority to represent the Trusts. 
 SECTION 4.08 Capitalized terms used herein without definition shall have the meanings ascribed to such terms in the Trust Agreements. 

 IN WITNESS WHEREOF, the parties hereto have caused this Agreement of Resignation, Appointment and
Acceptance to be duly executed and, in the case of the Successor Trustee, acknowledged all as of the day and year first above written. 
  

			
	GSS HOLDINGS II, INC.
	        as Trust Beneficial Owner
		
	 By:
	 	 /s/ Bernard J. Angelo

	 Name:
	 	 Bernard J. Angelo

	 Title:
	 	 Vice President

	
	 THE BANK OF NEW YORK
         as Prior Trustee

		
	 By:
	 	 /s/ Joseph A. Lloret

	 Name:
	 	 Joseph A. Lloret

	 Title:
	 	 Assistant Vice President

	
	 U.S. BANK NATIONAL ASSOCIATION
         as Successor Trustee

		
	 By:
	 	 /s/ Patricia M. Child

	 Name:
	 	 Patricia M. Child

	 Title:
	 	 Vice President

 ACKNOWLEDGED AND AGREED: 
  

			
	JPMORGAN CHASE BANK, N.A.
	        As Indenture Trustee with respect to each Trust
		
	By:	 	 /s/ Richard C. Tarnas

	Name:	 	Richard C. Tarnas
	Title:	 	Authorized Officer
	
	GENWORTH LIFE AND ANNUITY INSURANCE COMPANY
		
	By:	 	 /s/ Gary Prizzia

	Name:	 	Gary Prizzia
	Title:	 	Treasurer
		
	By:	 	 /s/ Robert W. McNutt

	Name:	 	Robert W. McNutt
	Title:	 	Assistant Treasurer

  

					
	STATE OF	  	)	 	
		  	:	 	ss
	COUNTY OF	  	)	 	

 BEFORE ME, the undersigned authority, on this
         day of                     , 2006, personally appeared
                                ,
                         of U.S. BANK NATIONAL ASSOCIATION, a national banking association, known to me (or proved to
me by introduction upon the oath of a person known to me) to be the person and officer whose name is subscribed to the foregoing instrument, and acknowledged to me that he/she executed the same as the act of such association for the purposes and
consideration herein expressed and in the capacity therein stated. 
 GIVEN UNDER MY HAND AND SEAL THIS
         DAY OF                     , 2006. 
 (SEAL) 
  

	
	 /s/ Melissa A. Rosal

	 NOTARY PUBLIC, STATE OF ILLINOIS

	 Print Name: Melissa A. Rosal
                                

	 Commission Expires: October 20, 2007

 Exhibit A 
  

										
	 Number of Genworth Global Funding Trust
	  	 Title of Notes
	  	Principal Amount	  	Date of Trust
Agreement	  	Issue Date
	2005-A	  	Floating Rate Secured Medium-Term Notes due 12/15/10	  	$	300,000,000	  	12/15/05	  	12/21/05
					
	2006-A	  	Floating Rate Secured Medium-Term Notes due 2/10/09	  	$	400,000,000	  	2/3/06	  	2/10/06
					
	2006-B	  	5.125% Secured Medium-Term Notes due 3/15/11	  	$	300,000,000	  	3/16/06	  	3/23/06
					
	2006-C	  	5.75% Secured Medium-Term Notes due 5/15/13	  	$	300,000,000	  	5/11/06	  	5/17/06
					
	2006-D	  	5.375% Secured Medium-Term Notes due 9/15/11	  	$	250,000,000	  	8/22/06	  	8/29/06
					
	2006-E	  	Floating Rate Secured Medium-Term Notes due 9/15/13	  	$	200,000,000	  	9/18/06	  	9/25/06
					
	2006-F	  	Extendible Secured Medium-Term Notes due 10/15/12	  	$	500,000,000	  	9/28/06	  	10/5/06Exhibit 10.1

 Exhibit 10.1 
 EXPENSE AND INDEMNITY AGREEMENT 
 This Expense and Indemnity Agreement (this “Agreement”) is
entered into as of October 1, 2006, by and between Genworth Life and Annuity Insurance Company, a stock life insurance company operating under a charter granted by the Commonwealth of Virginia (“GLAIC”), and U.S. Bank National Association,
a national banking association, as trustee (the “Trustee”), on behalf of itself and on behalf of each Trust organized in connection with the Program. 
 WHEREAS, in consideration of the Trustee providing services to each Trust created in connection with the Program and pursuant to the Program Documents under which the Trustee will have certain rights, duties and
obligations, GLAIC hereby agrees to the following compensation arrangements and terms of indemnity with the Trustee and reimbursement arrangements and terms of indemnity with each Trust organized in connection with the Program; and 
 WHEREAS, the Trustee is entering into this Agreement on behalf of itself and on behalf of each Trust to be organized in connection with the Program and,
therefore, this Agreement shall inure to the benefit of and be binding upon each such Trust. 
 NOW, THEREFORE, in consideration of the
agreements and obligations set forth herein and for other good and valuable consideration, the sufficiency of which is hereby acknowledged, each party hereby agrees as follows: 
 ARTICLE I 
 DEFINITIONS 
 Section 1.01 Definitions. All capitalized terms not otherwise defined herein will have the meanings set forth in the Standard Indenture Terms
attached as Exhibit 4.1 to Registration Statement on Form S-3 (File No. 333-128718) filed with the Securities and Exchange Commission (the “Commission”) by GLAIC on September 30, 2005, as amended by Amendment No. 1 filed
with the Commission on December 8, 2005. The following terms, as used herein, have the following meanings: 
 “Excluded
Amounts” means (i) any obligation of any Trust to make any payment to any Holder in accordance with the terms of the applicable Indenture or such Trust’s Notes, (ii) any obligation or expense of any Trust to the extent that
such obligation or expense has actually been paid utilizing funds available to such Trust from payments under the applicable Funding Agreement, (iii) any cost, loss, damage, claim, action, suit, expense, disbursement, tax, penalty or liability
of any kind or nature whatsoever resulting from or relating to any insurance regulatory or other governmental authority asserting that: (a) any Trust’s Notes are, or are deemed to be, (1) participations in the applicable Funding
Agreement or (2) contracts of insurance, or (b) the offer, purchase, sale and/or transfer of any Trust’s Notes and/or the pledge and collateral assignment of the applicable Funding Agreement by any Trust to the Indenture Trustee on
behalf of the Holders of such Trust’s Notes (1) constitutes the conduct of the business of insurance or reinsurance in any jurisdiction or (2) requires such Trust or any Holder of such Trust’s Notes to be licensed as an insurer,
insurance agent or broker in any jurisdiction, (iv) any cost, loss, damage, claim, action, suit, expense, disbursement, tax, penalty or liability of any kind 
  

 1 

 or nature whatsoever imposed on the Trustee that results from the bad faith, misconduct or negligence of the Trustee,
(v) any costs and expenses attributable solely to the Trustee’s administrative overhead unrelated to the Program, (vi) any tax imposed on fees paid to the Trustee, (vii) any withholding taxes imposed on or with respect of
payments made under the applicable Funding Agreement, the applicable Indenture or a Trust’s Note and (viii) any Additional Amounts paid to any Holder. 
 “Fees” means the fees agreed to between GLAIC and the Trustee as set forth in the fee schedule attached as Exhibit A to this Agreement. 
 “Obligation” means any and all (i) costs and expenses reasonably incurred by the Trustee (including the reasonable fees and
expenses of counsel) relating to the offering, sale or issuance of any Notes by any Trust under the Program or the administration of any Trust by the Trustee and (ii) costs, expenses and taxes of each Trust; provided, however, that Obligations
do not include Excluded Amounts. 
 ARTICLE II 
 SERVICES AND FEES 
 Section 2.01 Fees. GLAIC hereby agrees to pay the Trustee its Fees. Such
Fees may be subject to amendment in the event of a substantive change in the nature of the Trustee’s duties under the Program, as may be agreed to in writing from time to time by the Trustee and GLAIC. 
 Section 2.02 Payment of Obligations. (a) In the event that the Trustee delivers written notice and evidence, reasonably satisfactory to
GLAIC, of any Obligation of the Trustee or any Trust, GLAIC shall, upon receipt of such notice, promptly pay such Obligation. Notice of any Obligation (including any invoices) should be sent to GLAIC at its address set forth in Section 4.05
herein, or at such other address as such party shall hereafter furnish in writing. 
 (b) At the written request of GLAIC, the Trustee will
(i) from time to time execute all such instruments and other agreements and take all such other actions as may be reasonably necessary or desirable on behalf of itself or any Trust, or that GLAIC may reasonably request, in writing, to protect
any interest of GLAIC with respect to any Obligation or to enable GLAIC to exercise or enforce any right, interest or remedy it may have with respect to any such Obligation and (ii) release to GLAIC any amount received from GLAIC relating to
any Obligation or any portion of any Obligation, immediately after any such amount relating to such Obligation, or any portion of any such Obligation, is otherwise received by the Trustee or any Trust from a party other than GLAIC. 
 (c) GLAIC and the Trustee, on behalf of itself and each Trust, hereby agree that all payments due under this Agreement in respect of any Obligation shall
be effected, and any responsibility of GLAIC to pay such Obligation pursuant to this Agreement shall be discharged, by the payment by GLAIC to the account of the person to whom such Obligation is owed. For the avoidance of doubt, amounts due to the
Trustee hereunder are not subject to any caps which may be set forth in the Program Documents. 
  

 2 

 ARTICLE III 
 INDEMNIFICATION 
 Section 3.01 Indemnification. 
 (a) Subject to the remaining sections of this Article III, GLAIC covenants to fully indemnify and defend the Trustee and its officers, employees, agents
and directors (each, a “Trustee Indemnified Person”) for, and to hold them harmless against, any and all loss, liability, claim, damage or reasonable expense (including the reasonable compensation, expenses and disbursements of its
counsel) arising out of the acceptance by the Trustee, in its capacity as Trustee, of administration of the applicable Trust Agreement or any Trust and/or the performance of the Trustee’s duties and/or the exercise of the Trustee’s
respective rights under the applicable Trust Agreement, including the reasonable costs and expenses of defending itself against or investigating any claim of liability in the premises, except to the extent such loss, liability, claim, damage or
expense arises out of or is related to the bad faith, misconduct or negligence of the Trustee. Notwithstanding anything to the contrary, GLAIC shall have no obligation to indemnify or defend the Trustee for any loss, liability, claim, damage or
expense relating to (i) any costs and expenses attributable solely to the Trustee’s administrative overhead unrelated to the Program or (ii) any tax imposed on the Fees paid to the Trustee. 
 (b) Subject to the remaining sections of this Article III, GLAIC covenants to fully indemnify and defend each Trust and its respective representatives
(each, a “Trust Indemnified Person,” each Trust Indemnified Person and each Trustee Indemnified Person are referred to herein as an “Indemnified Person”) for, and to hold them harmless against, any and all loss, liability, claim,
damage or reasonable expense (including the reasonable compensation, expenses and disbursements of its counsel) arising out of the performance of each Trust’s duties and/or the exercise of each Trust’s respective rights under the
applicable Trust Agreement, including the reasonable costs and expenses of defending itself against or investigating any claim of liability in the premises, except to the extent such loss, liability, claim, damage or expense arises out of or is
related to the bad faith, misconduct or negligence of any Trust. 
 Section 3.02 Proceedings. An Indemnified Person shall give
prompt written notice to GLAIC of any action, suit or proceeding commenced or threatened against the Indemnified Person. In case any such action, suit or proceeding shall be brought involving an Indemnified Person, GLAIC may, in its sole discretion,
elect to assume the defense of the Indemnified Person, and, if it so elects, GLAIC shall, in consultation with such Indemnified Person, select counsel, reasonably acceptable to the Indemnified Person, to represent the Indemnified Person and pay the
reasonable fees and expenses of such counsel. In any such action, investigation or proceeding, the Indemnified Person shall have the right to retain its own counsel but GLAIC shall not be obligated to pay the fees and disbursements of such counsel
unless (i) GLAIC and the Indemnified Person shall have mutually agreed in writing to the retention of such counsel, (ii) the named parties to any such action, investigation or proceeding (including any impleaded parties) include both GLAIC
and the Indemnified Person and the Indemnified Person shall have reasonably and in good faith concluded that representation of both parties by the same counsel would be inappropriate due to actual or potential differing interests between them or
(iii) GLAIC fails, within ten (10) days prior to the date the first response or appearance is required to be made in any such proceeding, to assume the defense of such proceeding with counsel reasonably 
  

 3 

 satisfactory to the Indemnified Person; provided, that GLAIC has received written notice of such action, investigation or
proceeding at least sixty (60) days prior to the date the first response or appearance is required to be made; provided, further, that in the event the Indemnified Person has received notice of such action, suit or proceeding on a day which is
less than 60 days prior to the date the first response or appearance is required to be made, the Indemnified Person shall provide GLAIC with prompt written notice of such action, suit or proceeding and, for purposes of this Section 3.02, such notice
shall be considered timely. It is understood that GLAIC shall not, in connection with any proceeding or related proceeding in the same jurisdiction, be liable for the fees and expenses of more than one separate firm (in addition to any local
counsel) for all Indemnified Persons. 
 Section 3.03 Contribution. Solely to the extent, if any, that the indemnification
provided for herein is finally determined by a court of competent jurisdiction to be invalid or unenforceable, in whole or in part, in accordance with its terms, then GLAIC shall contribute to the amount paid or payable by an Indemnified Person as a
result of such liability in such proportion as is appropriate to reflect the relative benefits received by GLAIC and the Trust (if the Trust is not an Indemnified Person), on one hand, and the Trustee or the Trust (if the Trust is an Indemnified
Person), on the other hand, from the transactions contemplated by the Program Documents. For this purpose, the benefits received by GLAIC or the Trust (if applicable) shall be the aggregate value of the relevant Collateral, and the benefits received
by the Trustee shall be the Fees it has been paid up to that point, as the Trustee, less costs and unreimbursed expenses incurred by it, as Trustee, in relation to such Collateral, and the benefits received by the Trust (if applicable) shall be
determined by the Trustee and GLAIC. If, however, the allocation provided by the immediately preceding two sentences is not permitted by applicable law, then GLAIC shall contribute to such amount paid or payable by the Indemnified Person in such
proportion as is appropriate to reflect not only such relative benefits but also the relative fault of GLAIC and the Trust (if applicable) (but solely to the extent such fault results from or is attributable to the Trustee’s bad faith, willful
misconduct or negligence), on the one hand, and the Trustee or the Trust (if applicable), on the other hand, in connection with the actions or omissions which resulted in such liability. 
 Section 3.04 Subrogation. GLAIC shall be subrogated to any right of the Indemnified Person in respect of the matter as to which any indemnity
was paid hereunder. 
 Section 3.05 Settlement. The Indemnified Person may not settle any action, investigation or proceeding
without the consent of GLAIC, not to be unreasonably withheld. 
 Section 3.06 Survival. Notwithstanding any provision contained
herein to the contrary, the obligations of GLAIC under this Article III to any Indemnified Person shall survive the termination of this Agreement pursuant to Section 4.03 herein. 
 Section 3.07 General. The indemnification provided for herein supersedes in all respects any indemnification obligation of GLAIC contained in
any other Program Document to which any Trust or the Trustee is or becomes party. 
 ARTICLE IV 
 MISCELLANEOUS 
 Section 4.01
Waiver. No waiver, modification or amendment of this Agreement shall be valid unless executed in writing by the parties hereto. 
  

 4 

 Section 4.02 Governing Law. This Agreement shall be governed by and construed in accordance
with the laws of the State of New York, without regard to conflicts of laws principles. 
 Section 4.03 Termination. This
Agreement shall terminate and be of no further force and effect upon the date on which (i) there are no Fees and there is no Obligation (other than any Obligation directly related to the indemnification obligations of GLAIC set forth in Article
III hereof) due and payable under this Agreement and (ii) each Program Document has terminated; provided, however, that this Agreement shall continue to be effective or shall be reinstated, as the case may be, if at any time any Trust or the
Trustee must restore payment of any sums paid under any Obligation or under this Agreement for any reason whatsoever or the Trustee or a Trust becomes subject to a claim. This Agreement is continuing, irrevocable, unconditional and absolute.

 Section 4.04 Third Party Beneficiary. GLAIC understands and agrees that each Trust shall be a third party beneficiary of the
obligations of GLAIC under this Agreement, subject to the limitations set forth in this Agreement. Other than each Trust, the Trustee and each Indemnified Person, no other Person shall have any legal or equitable right, remedy or claim under or in
respect of this Agreement or any covenant, condition or provision contained herein. 
 Section 4.05 Notices. All notices,
demands, instructions and other communications required or permitted to be given to or made upon either party hereto shall be in writing (including by facsimile transmission) and shall be personally delivered or sent by guaranteed overnight delivery
or by facsimile transmission (to be followed by personal or guaranteed overnight delivery) and shall be deemed to be given for purposes of this Agreement on the day that such writing is received by the intended recipient thereof in accordance with
the provisions of this Section 4.05. Unless otherwise specified in a notice sent or delivered in accordance with the foregoing provisions of this Section 4.05, notices, demands, instructions and other communications in writing shall be
given to or made upon the respective parties thereto at their respective addresses (or their respective facsimile numbers) indicated below: 
 To the Trust: 
 Genworth Global Funding Trust (followed by the appropriate number of the Trust 
 designated in the Pricing Instrument) 
 c/o
U.S. Bank National Association 
 Corporate Trust Services 
 209 S. LaSalle Street, Suite 300 
 Chicago, Illinois 60604 
 Attention: Patricia Child, VP 
 Facsimile:
(312) 325-8905 
 To GLAIC: 
 Genworth Life and Annuity Insurance Company 
 6610 West Broad Street 
 Richmond, Virginia 23230 
 Attention:
Treasury, Building 1 
 Facsimile: (804) 662-7777 
  

 5 

 with a copy to: 
 Genworth Life and Annuity Insurance Company 
 6610 West Broad Street 
 Richmond, Virginia 23230 
 Attention: Heather
Harker, Esq. 
 Facsimile: (804) 281-6005 
 To the Trustee: 
 U.S. Bank National Association 
 Corporate Trust Services 
 209 S. LaSalle
Street, Suite 300 
 Chicago, Illinois 60604 
 Attention: Patricia Child, VP 
 Facsimile: (312) 325-8905 
 Section 4.06 Trust Administration. It is understood and agreed by GLAIC that whenever any Trust is required to act under the terms of the
Indenture, GLAIC will act on behalf of such Trust including, without limitation, ensuring that such Trust complies with Article III of the Indenture and with the Trust Indenture Act or direct the Trustee to act on behalf of such Trust in instances
in which the Trustee determines that the Trustee can act; provided, that at no time shall the Trustee be under a duty to exercise discretion under the Indenture or act or refrain from acting under the Indenture in the absence of instruction from
GLAIC. In addition, GLAIC shall prepare and file or cause the preparation and filing of all documents and instruments required of each Trust under the applicable law, unless otherwise agreed to by GLAIC and the Trustee on behalf of each such Trust.
The Trustee shall execute such documents and instruments as GLAIC may reasonably request. 
 Section 4.07 Counterparts. This
Agreement may be executed in counterparts (including by facsimile transmission), each of which when so executed and delivered shall be deemed an original, but all of such counterparts shall together constitute one and the same instrument.

  
 [The remainder of this page left intentionally blank.]

  

 6 

 IN WITNESS WHEREOF, the parties have executed this Expense and Indemnity Agreement by their duly
authorized officers as of the date hereof. 
  

			
	 GENWORTH LIFE AND ANNUITY
 INSURANCE
COMPANY

		
	By:	 	  
	Name:	 	Gary T. Prizzia
	Title:	 	Treasurer
		
	By:	 	  
	Name:	 	Robert W. McNutt
	Title:	 	Assistant Treasurer
	
	U.S. BANK NATIONAL ASSOCIATION, as Trustee on behalf of itself and each Trust organized in connection with the Program
		
	By:	 	  
	Name:	 	
	Title:	 	

  

 7 

 Exhibit A 
  

 A-1

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