Document:

Exhibit 10.11

 

LICENSE AGREEMENT

AMENDMENT #2

  

WHEREAS, effective as of December 1, 2014,
and as further amended September 20, 2016, Miromatrix Medical Inc., a corporation organized under the laws of the State of Delaware and
having an office at 10399 West 70th Street, Eden Prairie, MN 55344 ("Miromatrix") and Mayo Foundation for Medical Education
and Research, a not for profit corporation with an address at 200 First Street SW, Rochester, MN 55905 ("Mayo") executed a License
Agreement (the "Agreement") for Services as outlined in the Agreement.

 

WHEREAS, Miromatrix and Mayo wish to amend
said Agreement.

 

NOW, THEREFORE, Miromatrix and Mayo agree
as follows:

 

		1.	The Term of the Agreement shall be extended for an additional one year period. Accordingly, the new expiration date of the Agreement
shall be December 31, 2018.

 

		2.	Miromatrix has agreed to provide additional funding of $60,000 for year three of the Project. Accordingly, the attached Exhibit B-1
shall amend Section 3 of the Agreement.

 

		3.	Except as specifically provided herein, the terms and conditions of the Agreement shall remain in force.

 

IN WITNESS WHEREOF, the Parties have executed
this Amendment which shall be effective as of the last dated signature below.

 

	MIROMATRIX MEDICAL INC.	 	MAYO FOUNDATION FOR MEDICAL

 EDUCATION AND RESEARCH
	 	 	 
	By:	/s/ Jeff Ross	 	By:	/s/ Randall S. Jones
	 	 	 	 	 
	Name:	Jeff Ross	 	Name:	Randall S. Jones
	 	 	 	 	 
	Title:	CEO	 	Title:	Operations Manager
	 	 	 	 	 
	Date:	9/5/2017	 	Date:	9/12/2017

 

     

     

    

 

Budget - Exhibit B-1

 

TT
MAYO CLINIC

 

PI Name:     Stott Nyberg, MD,
PhD 

MCR Funding Proposal Number: FP86573-41-A1-41 

Sponsor; Miromatrix Medical Inc. 

Date: 8/2/17

 

Study
Title: Amendment #2: Miromatrix/Mayo Transplantable Liver Project (Nyberg}

 

	 	 	1/1/18-12/31/18**	 
	 	 	 	 
	Personnel: (Includes salary and benefits"):	 	 	 
	Dr. Scott Nyberg, PI	 	 	23,076	 
	 	 	 	 	 
	Lab Supplies:	 	 	 	 
	Hapatccyte Isolation	 	 	7,693	 
	Large Animal Care - Chronic	 	 	15,385	 
	 	 	 	 	 
	Sub-Total	 	 	46,154	 
	Indirects (30%)	 	 	13,846	 
	 	 	 	 	 
	BUDGET TOTAL	 	 	60,000	 

 

Payment Terms: 100% due upon execution of contract

 

*Salary and benefit rate information
is confidential. Mayo cannot share individual costs or rate information, as this would be against Mayo policy

 

' This budget only reflects the
budget for year 3 which is being added with amendment 2.

 

Years 1-2 have already been negotiated.

 

NOTE: This is only a budget estimate, budgetay
be adjusted due to the following changes: salaries, fees, procedures, etc.

 

Prepared by:

 

Sherry Foster, Sponsored Projects SpecialistExhibit 10.12

 

AMENDMENT NO. 3

TO

LICENSE AGREEMENT

BETWEEN

MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH

AND

MIROMATRIX MEDICAL INC.

 

THIS Amendment No. three (“Amendment No.
3”), effective as of February, 21, 2017, to the License Agreement (“Agreement”) with an effective date of December 1,
2014, between Mayo Foundation for Medical Education and Research, a Minnesota charitable corporation having its principal place of business
at 200 pt Street S W, Rochester, Minnesota 55905-0001 (“MAYO”) and Miromatrix Medical Inc., a corporation having its principal
place of business at 18683 Bearpath Trail, Eden Prairie, Minnesota 55347 (“COMPANY”) is hereby amended under the following
terms:

 

		1.	The following invention disclosure and provisional patent application are determined to be jointly owned Intellectual Property, under
the terms of Section 8. Intellectual Property Rights in the Agreement: Mayo Invention Disclosure # 2017-266: “Use of Resected Liver
Serum for Whole Liver-Engineering”, Mayo Inventor - Scott L. Nyberg M.D., Ph.D. and Provisional Patent Application Docket No.: 3242.007PRV
Title: Use of Resected Liver Serum for Whole Liver-Engineering.

 

The terms of this Amendment No. 3 supersede any conflicting or inconsistent
tem1s in the Agreement. All other provisions of the original Agreement remain in full force and effect.

 

This Agreement may be executed in any number of counterparts which,
when taken together, will constitute an original, and photocopy, facsimile, electronic or other copies shall have the same effect for
all purposes as an ink-signed original. Each Party hereto consents to be bound by photocopy or facsimile signatures of such Party’s
representative hereto.

 

	Mayo Foundation for Medical Education and Research	 	Miromatrix Medical Inc.
	 	 	 
	By	/s/Daniel D. Estes	 	By	/s/ Jeff Ross
	 	Name:	Daniel D. Estes	 	 	Name:	 Jeff Ross
	 	Title:	Assistant Treasurer	 	 	Title:	CEO
	 	 	 
	Date: 9/15/2017	 	Date:	9/25/2017Exhibit 10.13

 

LICENSE AGREEMENT

AMENDMENT #4

 

WHEREAS,
effective as of December 1, 2014, and as further amended September 20, 2016, September 12, 2017, and February 21, 2017, Miromatrix
Medical Inc., a corporation organized under the laws of the State of Delaware and having an office 10399 West 70th Street, Eden Prairie,
MN 55344 ("Miromatrix") and Mayo Foundation for Medical Education and Research, a not for profit corporation with an address
at 200 First Street SW, Rochester, MN 55905 ("Mayo") executed a License Agreement (the "Agreement") for Services as
outlined in the Agreement.

 

WHEREAS, Miromatrix and Mayo wish to amend said Agreement.

 

NOW, THEREFORE, Miromatrix and Mayo agree as follows:

 

		1.	The Term of the Agreement shall be extended for an additional 6 month period. Accordingly,
the new expiration date of the Agreement shall be June 30, 2019.

		2.	Miromatrix has agreed to provide additional funding of $444,448 for year three
of the Project. Accordingly, the attached Exhibit B-2 shall amend Section 3 of the Agreement.

		3.	The parties wish to add an additional project to the Statement of Work. Accordingly,
the attached Exhibit A-1 shall hereby amend the Statement of Work/the Project.

		4.	Except as specifically provided herein, the terms and conditions of the Agreement
shall remain in force.

 

IN WITNESS WHEREOF, the
Parties have executed this Amendment which shall be effective as of the last dated signature below.

 

	MIROMATRIX MEDICAL INC.  	 	MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH    
   
	 	 	 
	By:	/s/ Jeff Ross	 	By:	/s/ Virginia M. Bruce
	Name:	Jeff Ross	 	Name:	Virginia M. Bruce
	Title:	CEO	 	Title:	Director, Legal Contract Adminis-tration
	Date:	1/23/2018	 	Date:	1/24/2018

 

     

     

    

 

Budget - Exhibit
B-2

 

	U MAYO CLINIC  

                                                          

                                                         PI
Name:          Scott Nyberg, MD, PhD  

                                                          

                                                         MCR Funding Proposal Number: FP86573-A1-A1-A1-A1  

                                                          

                                                         Sponsor: Miromatrix Medical Inc.

Date: 12/27/07              

	Study Title: Amendment #4: Miromatrix/Mayo Transplantable Liver Project (Nyberg)

 

	 	 	1/1/18-12/31/18**	 
	Personnel: (Includes salary and benefits*):	 	$	77,683	 
	Dr. Scott Nyberg, PI	 	 	 	 
	Bruce Amiot, Business Analyst	 	 	 	 
	 	 	 	 	 
	Lab Supplies:	 	 	 	 
	Media	 	$	108,000	 
	ICP Probes	 	$	29,000	 
	 	 	 	 	 
	Internal Services:	 	 	 	 
	Cr scans	 	$	7,200	 
	Pigs + OR	 	$	72,000	 
	Pig Harvests	 	$	24,000	 
	Auto Transplants	 	$	24,000	 
	 	 	 	 	 
	Sub-Total	 	$	341,883	 
	lndirects (30%)	 	$	102,565	 
	 	 	 	 	 
	BUDGET TOTAL	 	$	444,448	 

 

Payment Terms: The total budget above will be payable in four quarterly payments of $111,112 each. The first payment of $111,112 will be payable upon execution of the contract amendment. The remaining three payments will be invoiced at 3 months, 6 months, and 12 months after contract amendment execution.

 

*Salary and benefit rate information is confidential. Mayo cannot share individual costs or rate information, as this would be against Mayo policy

 

** This budget only reflects the additional funds that are being added with amendment #4.

 

     

     

    

 

Exhibit A-1

 

Project 1: Implantation of a revascularized decellularized
liver graft with autologous portal hepatocyte seeding post transplantation.

 

Project 2: The model development and testing of a recellularized
liver grafts to provide functional support in a pig model for 48 hours.Exhibit 10.14

 

LICENSE AGREEMENT

AMENDMENT #5

 

WHEREAS, effective as of December 1, 2014,
and as further amended, Miromatrix Medical Inc., a corporation organized under the laws of the State of Delaware and having an office
10399 West 70th Street, Eden Prairie, MN 55344 (“Miromatrix”) and Mayo Foundation for Medical Education and Research, a not
for profit corporation with an address at 200 First Street SW, Rochester, MN 55905 (“Mayo”) executed a License Agreement (the
 “Agreement”) for Services as outlined in the Agreement.

 

WHEREAS, Miromatrix and Mayo wish to amend
said Agreement.

 

NOW, THEREFORE, Miromatrix and Mayo agree
as follows:

 

		1.	The Term of the Agreement shall be extended to March 31, 2020.

 

		2.	Miromatrix has agreed to provide additional funding of $200,000 for extension described in #1 above. Accordingly, the attached Exhibit
B-3 shall amend Section 3 of the Agreement.

 

		3.	Except as specifically provided herein, the terms and conditions of the Agreement shall remain in force.

 

IN WITNESS WHEREOF, the Parties have executed
this Amendment which shall be effective as of the last dated signature below.

 

	MIROMATRIX
    MEDICAL INC.	 	MAYO FOUNDATION
    FOR MEDICAL EDUCATION AND RESEARCH
		 	 
	 	 	 
	By:	/s/ Jeff Ross	 	By:	/s/ Brenda L. Burns
	 	 	 
	Name:	Jeff Ross	 	Name:	Brenda L. Burns
	 	 	 
	Title:	CEO	 	Title:	Sr. Contract Manager
	 	 	 
	Date:	5/12/2019	 	Date:	5/7/2019

 

     

     

    

 

Budget – Exhibit B-3

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00328-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00328-of-00352.parquet"}], [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00328-of-00352.parquet"}], [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00328-of-00352.parquet"}]]