Document:

Exhibit 10.1

 

SUBSCRIPTION AGREEMENT

 

SUBSCRIPTION AGREEMENT
(this “Agreement”) made as of the last date set forth on the signature page hereof between Protea Biosciences Group,
Inc. (the “Company”), and the undersigned (the “Subscriber”).

 

WITNESSETH:

 

WHEREAS, the Company is
conducting a private offering (the “Offering”) of up a minimum of $500,000 and up to a maximum of $5,000,000
of units of our securities (the “Units”), consisting of a maximum of (a) 5,000,000 shares of our Series A convertible
preferred stock, par value $0.0001 per share (the “Series A Preferred Stock”), (b) 18 month warrants to purchase
up to 66,666,667 shares of common stock, par value $0.0001 per share (the “Common Stock”), at an exercise price
of $0.09 per share (the “Class A Warrants”), and (c) five year warrants purchase up to 66,666,667 shares of
Common Stock at an exercise price of $0.1125 per share (the “Class B Warrants” and together with the Class A
Warrants, collectively, the “Warrants”). Upon the occurrence of a “Conversion Event” (defined
below) the Series A Preferred Stock will automatically convert at a conversion price of $0.075 per share into a maximum of 66,666,667
shares of Common Stock, subject to certain adjustments. The Series A Preferred Stock and the Warrants are sometimes referred to
herein collectively as the “Securities;” and

 

WHEREAS, a minimum of 50
Units for an aggregate purchase price of $500,000 (the “Minimum Offering”) and a maximum of 500 Units for an
aggregate purchase price of $5,000,000 (the “Maximum Offering”) are being offered by the Company in the Offering;
each Unit consisting of (a) 10,000 shares of Series A Preferred Stock at a purchase price of $1.00 per share that converts into
133,333 shares of Common Stock, (b) Class A Warrants to purchase 133,333 shares of Common Stock at an exercise price of $0.09 per
share, and (c) Class B Warrants to purchase 133,333 shares of Common Stock at an exercise price of $0.1125 per share; and

 

WHEREAS, the Company has
retained Laidlaw & Company (UK) Ltd. to act as its placement agent in connection with the sale of the Units pursuant to this
Agreement (the “Placement Agent”);

 

WHEREAS, the Offering is
on a “best efforts, all-or-none” basis to attain the Minimum Offering and on a “reasonable efforts” basis
as to the remaining Units to be sold up to the Maximum Offering, to a limited number of “accredited investors” (as
that term is defined by Rule 501(a) of Regulation D (“Regulation D”) promulgated by the Securities and Exchange
Commission (the “SEC”) under the Securities Act of 1933, as amended (the “Securities Act”);

 

WHEREAS, the Company and
each Subscriber is executing and delivering this agreement in reliance upon the exemption from securities registration afforded
by Section 4(a)(2) of the Securities Act and Rule 506 of Regulation D promulgated by the SEC under the Securities Act;

 

WHEREAS the subscription
for the Securities will be made in accordance with and subject to the terms and conditions of this Subscription Agreement and the
Company’s Confidential Private Placement Memorandum dated September 29, 2016, together with all amendments thereof and supplements
and exhibits thereto and as such may be amended from time to time (the “Private Placement Memorandum”); and

 

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WHEREAS, the minimum subscription
from qualified Subscribers shall be one full Unit for a minimum purchase price of $10,000, although, the Company and the Placement
Agent may accept subscriptions from qualified investors for lesser amounts in their sole discretion; and

 

WHEREAS, as disclosed in
the Private Placement Memorandum, the Company intends to amend its Certificate of Incorporation to increase its authorized shares
of Common Stock to 500,000,000 shares of Common Stock (the “Charter Amendment”) and complete such Charter Amendment
by October 31, 2016 and with a 1-for-25 reverse stock split of our outstanding Common Stock which has previously been authorized
by our stockholders (the “Reverse Stock Split”) to be completed on or prior to the Termination Date of this
Offering, thereby reducing the outstanding number of shares of “fully-diluted Common Stock” (as described in the Private
Placement Memorandum) to approximately 19,693,535 shares of Common Stock; and

 

WHEREAS, upon the filing
of the Charter Amendment with the Secretary of State of the State of Delaware (the “Conversion Event”), the
Series A Preferred Stock shall automatically, and without any further action on the part of the Company or the holders,
convert into shares of Common Stock (the “Conversion Shares”) at a conversion price of $0.075 per share (the
“Conversion Price”), subject to increase to $1.875 per share as a result of the Reverse Stock Split and certain
other adjustments; and

 

WHEREAS, consummation of
the Charter Amendment will require the affirmative consent of the holders of a majority of the Common Stock that was outstanding
as at September 20, 2016, as set forth in our definitive Rule 14A proxy statement dated September 23, 2016, and consummation of
the Reverse Stock Split will require (a) the filing of an amendment to our Certificate of Incorporation with the Delaware Secretary
of State, and (b) obtaining the approval of the Financial Industry Regulatory Authority (“FINRA”); and

 

WHEREAS, the Subscriber
desires to purchase such number of Units as are set forth on the signature page hereof on the terms and conditions hereinafter
set forth.

 

NOW, THEREFORE, in consideration
of the premises and the mutual representations and covenants hereinafter set forth, the parties hereto do hereby agree as follows:

 

		I.	SUBSCRIPTION FOR UNITS OF SECURITIES AND REPRESENTATIONS
BY SUBSCRIBER

 

1.1      Subject
to the terms and conditions hereinafter set forth, the Subscriber hereby subscribes for and agrees to purchase from the Company,
and the Company subject to its rights to accept or reject this subscription, agrees to sell to the Subscriber, such number of Units
for the aggregate purchase price as is set forth on the signature page hereof. The purchase price is payable by wire transfer,
to be held in escrow until the conditions to closing are achieved, to Signature Bank, the escrow agent (the “Escrow Agent”).

 

1.2      The
Securities will be offered for sale until the earlier of (i) the date upon which subscriptions for the Maximum Offering offered
hereunder have been accepted, (ii) December 31, 2016 (subject to the right of the Company and the Placement Agent to extend the
Offering until March 31, 2017 without further notice to investors), or (iii) the date upon which the Company elects to terminate
the Offering (the “Termination Date”). The Offering is being conducted on a “reasonable best-efforts”
basis, up to the Maximum Offering.

 

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1.3      The
Company may hold an initial closing (“Initial Closing”) at any time after receipt of accepted subscriptions
equal to or greater than Minimum Offering. After the Initial Closing, subsequent closings with respect to additional Securities
may take place at any time prior to the Final Termination Date as determined by the Company, with respect to subscriptions accepted
prior to the Final Termination Date (each such closing, together with the Initial Closing, being referred to as a “Closing”).
The Company may elect to terminate the Offering at any time prior to the Final Termination Date (the earlier of the date of any
such termination or the Final Termination date, the “Termination Date”). The last Closing of the Offering, occurring
on or prior to the Termination Date, shall be referred to as the “Final Closing”. Any subscription documents
or funds received after the Final Closing will be returned, without interest or deduction. In the event that any Closing does not
occur prior to the Final Termination Date, all amounts paid by the Subscriber shall be returned to the Subscriber, without interest
or deduction. The Subscriber may revoke its subscription and obtain a return of the subscription amount paid to the Escrow Account
at any time before the date of the Initial Closing by providing written notice to the Placement Agent, the Company and the Escrow
Agent as provided in Section 6.1 below. Upon receipt of a revocation notice from the Subscriber prior to the date of the Initial
Closing, all amounts paid by the Subscriber shall be returned to the Subscriber, without interest or deduction. The Subscriber
may not revoke this subscription or obtain a return of the subscription amount paid to the Escrow Agent on or after the date of
the Initial Closing. Any subscription received after the Initial Closing but prior to the Termination Date shall be irrevocable.

 

1.4      The
Subscriber recognizes that the purchase of the Securities involves a high degree of risk including, but not limited to, the following:
(a) the Company has a limited operating history and requires substantial funds in addition to the proceeds of the Offering; (b)
an investment in the Company is highly speculative, and only investors who can afford the loss of their entire investment should
consider investing in the Company and the Securities; (c) the Subscriber may not be able to liquidate its investment; (d) transferability
of the Securities is extremely limited; (e) in the event of a disposition, the Subscriber could sustain the loss of its entire
investment; (f) the Company has not paid any dividends since its inception and does not anticipate paying any dividends; and (g)
the other risks associated with the Company’s business, financial situation and the Offering set forth in the Private Placement
Memorandum.

 

1.5      At
the time such Subscriber was offered the Securities, it was, and as of the date hereof it is, and on each date on which it converts
the Series A Preferred Stock and/or exercises any Warrants it will be an “accredited investor” as defined in Rule 501(a)
under the Securities Act, as indicated by the Subscriber’s responses to the questions contained in Article VII hereof, and
that the Subscriber is able to bear the economic risk of an investment in the Securities.

 

1.6      The
Subscriber hereby acknowledges and represents that (a) the Subscriber has knowledge and experience in business and financial matters,
prior investment experience, including investment in securities that are non-listed, unregistered and/or not traded on a national
securities exchange or the Subscriber has employed the services of a “purchaser representative” (as defined in Rule
501 of Regulation D), attorney and/or accountant to read all of the documents furnished or made available by the Company both to
the Subscriber and to all other prospective investors in the Securities to evaluate the merits and risks of such an investment
on the Subscriber’s behalf; (b) the Subscriber recognizes the highly speculative nature of this investment; and (c) the Subscriber
is able to bear the economic risk that the Subscriber hereby assumes.

 

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1.7      The
Subscriber hereby acknowledges receipt and careful review of this Agreement, the Private Placement Memorandum, including the Registration
Rights Agreement annexed as Exhibit B thereto, the form of Certificate of Designations of the Series A Preferred
Stock annexed as Exhibit C thereto, the form of Class A Warrant annexed as Exhibit D thereto, the form
of the Class B Warrant annexed as Exhibit E thereto, and all other exhibits to the Private Placement Memorandum,
including the Company’s Annual Report on Form 10-K for the year ended 2015 and its Quarterly Report on Form 10-Q for the
fiscal quarter ended June 30, 2016 (collectively referred to as the “Transaction Documents”), and has received
any additional information that the Subscriber has requested from the Company, and has been afforded the opportunity to ask questions
of and receive answers from duly authorized officers or other representatives of the Company concerning the Company and the terms
and conditions of the Offering; provided, however that no investigation performed by or on behalf of the Subscriber shall limit
or otherwise affect its right to rely on the representations and warranties of the Company contained herein, except to the extent
that the Subscriber had actual knowledge at the time of Closing that any such representation or warranty was untrue.

 

1.8     (a)          In
making the decision to invest in the Securities, the Subscriber has relied solely upon the information provided by the Company
in the Transaction Documents. To the extent necessary, the Subscriber has retained, at its own expense, and relied upon appropriate
professional advice regarding the investment, tax and legal merits and consequences of this Agreement and the purchase of the Securities
hereunder. The Subscriber disclaims reliance on any statements made or information provided by any person or entity in the course
of Subscriber’s consideration of an investment in the Securities other than the Transaction Documents.

 

(b)        The
Subscriber represents that (i) the Subscriber was contacted regarding the sale of the Securities by the Placement Agent with whom
the Subscriber had a prior substantial pre-existing relationship and (ii) it did not learn of the offering of the Securities by
means of any form of general solicitation or general advertising, and in connection therewith, the Subscriber did not (A) receive
or review any advertisement, article, notice or other communication published in a newspaper or magazine or similar media or broadcast
over television or radio, whether closed circuit, or generally available; or (B) attend any seminar meeting or industry investor
conference whose attendees were invited by any general solicitation or general advertising.

 

1.9      The
Subscriber hereby acknowledges that the Offering has not been reviewed by the SEC nor any state regulatory authority since the
Offering is intended to be exempt from the registration requirements of Section 5 of the Securities Act, pursuant to Regulation
D. The Subscriber understands that the Securities have not been registered under the Securities Act or under any state securities
or “blue sky” laws and agrees not to sell, pledge, assign or otherwise transfer or dispose of the Securities unless
they are registered under the Securities Act and under any applicable state securities or “blue sky” laws or unless
an exemption from such registration is available.

 

1.10    The
Subscriber understands that the Securities have not been registered under the Securities Act by reason of a claimed exemption under
the provisions of the Securities Act that depends, in part, upon the Subscriber’s investment intention and investment qualification.
In this connection, the Subscriber hereby represents that the Subscriber is purchasing the Securities for the Subscriber’s
own account for investment and not with a view toward the resale or distribution to others; provided, however, that nothing contained
herein shall constitute an agreement by the Subscriber to hold the Securities for any particular length of time and the Company
acknowledges that the Subscriber shall at all times retain the right to dispose of its property as it may determine in its sole
discretion, subject to any restrictions imposed by applicable law. The Subscriber, if an entity, further represents that it was
not formed for the purpose of purchasing the Securities.

 

1.11    The
Subscriber consents to the placement of a legend on any certificate or other document evidencing the Securities and, when issued,
the shares of Common Stock issuable upon conversion of the Series A Preferred Stock (the “Conversion Shares”)
and exercise of the Warrants (the “Warrant Shares” and collectively with the Conversion Shares, the “Shares”)
that such securities have not been registered under the Securities Act or any state securities or “blue sky” laws and
setting forth or referring to the restrictions on transferability and sale thereof contained in this Agreement. The Subscriber
is aware that the Company will make a notation in its appropriate records with respect to the restrictions on the transferability
of such Securities or the Shares.

 

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1.12    The
Subscriber hereby represents that the address of the Subscriber furnished by Subscriber on the signature page hereof is the Subscriber’s
principal residence if Subscriber is an individual or its principal business address if it is a corporation or other entity.

 

1.13    Such
Subscriber understands that the Securities (including the Shares) are “restricted securities” and have not been registered
under the Securities Act or any applicable state securities law and is acquiring the Securities as principal for its own account
and not with a view to or for distributing or reselling such Securities or any part thereof in violation of the Securities Act
or any applicable state securities law, has no present intention of distributing any of such Securities in violation of the Securities
Act or any applicable state securities law and has no direct or indirect arrangement or understandings with any other persons to
distribute or regarding the distribution of such Securities in violation of the Securities Act or any applicable state securities
law. Furthermore, such Subscriber is not purchasing the Securities as a result of any advertisement, article, notice or other communication
regarding the Securities published in any newspaper, magazine or similar media or broadcast over television or radio or presented
at any seminar or any other general solicitation or general advertisement.

 

1.14    The
Subscriber represents that the Subscriber has full power and authority (corporate, statutory and otherwise) to execute and deliver
this Agreement and to purchase the Securities. This Agreement constitutes the legal, valid and binding obligation of the Subscriber,
enforceable against the Subscriber in accordance with its terms.

 

1.15    If
the Subscriber is a corporation, partnership, limited liability company, trust, employee benefit plan, individual retirement account,
Keogh Plan, or other tax-exempt entity, it is authorized and qualified to invest in the Company and the person signing this Agreement
on behalf of such entity has been duly authorized by such entity to do so.

 

1.16    The
Subscriber acknowledges that if he or she is a Registered Representative of a Financial Industry Regulatory Authority (“FINRA”)
member firm, he or she must give such firm the notice required by the FINRA’s Rules of Fair Practice, receipt of which must
be acknowledged by such firm in Section 7.4 below.

 

1.17    To
effectuate the terms and provisions hereof, the Subscriber hereby appoints the Placement Agent as its attorney-in-fact (and the
Placement Agent hereby accepts such appointment) for the purpose of carrying out the provisions of the Escrow Agreement by and
between the Company, the Placement Agent and Escrow Agent (the “Escrow Agreement”) including, without limitation,
taking any action on behalf of, or at the instruction of, the Subscriber and executing any release notices required under the Escrow
Agreement and taking any action and executing any instrument that the Placement Agent may deem necessary or advisable (and lawful)
to accomplish the purposes hereof. All acts done under the foregoing authorization are hereby ratified and approved and neither
the Placement Agent nor any designee nor agent thereof shall be liable for any acts of commission or omission, for any error of
judgment, for any mistake of fact or law except for acts of gross negligence or willful misconduct. This power of attorney, being
coupled with an interest, is irrevocable while the Escrow Agreement remains in effect.

 

1.18    The
Subscriber agrees not to issue any public statement with respect to the Subscriber’s investment or proposed investment in
the Company or the terms of any agreement or covenant between them and the Company without the Company’s prior written consent,
except such disclosures as may be required under applicable law or under any applicable order, rule or regulation.

 

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1.19    The
Subscriber understands, acknowledges and agrees with the Company that this subscription may be rejected, in whole or in part, by
the Company, in the sole and absolute discretion of the Company, at any time before any Closing notwithstanding prior receipt by
the Subscriber of notice of acceptance of the Subscriber’s subscription.

 

1.20    The
Subscriber acknowledges that the information contained in the Transaction Documents or otherwise made available to the Subscriber
is confidential and non-public and agrees that all such information shall be kept in confidence by the Subscriber and neither used
by the Subscriber for the Subscriber’s personal benefit (other than in connection with this subscription) nor disclosed to
any third party for any reason, notwithstanding that a Subscriber’s subscription may not be accepted by the Company; provided,
however, that (a) the Subscriber may disclose such information to its affiliates and advisors who may have a need for such information
in connection with providing advice to the Subscriber with respect to its investment in the Company so long as such affiliates
and advisors have an obligation of confidentiality, and (b) this obligation shall not apply to any such information that (i) is
part of the public knowledge or literature and readily accessible at the date hereof, (ii) becomes part of the public knowledge
or literature and readily accessible by publication (except as a result of a breach of this provision) or (iii) is received from
third parties without an obligation of confidentiality (except third parties who disclose such information in violation of any
confidentiality agreements or obligations, including, without limitation, any subscription or other similar agreement entered into
with the Company).

 

1.21    The
Subscriber will indemnify and hold harmless the Company and the Placement Agent and, where applicable, their respective directors,
officers, employees, agents, advisors, affiliates and shareholders, and each other person, if any, who controls any of the foregoing
(collectively, the “Issuer Indemnified Parties”) from and against any and all loss, liability, claim, damage
and expense whatsoever (including, but not limited to, any and all fees, costs and expenses whatsoever reasonably incurred in investigating,
preparing or defending against any claim, lawsuit, administrative proceeding or investigation whether commenced or threatened)
(a “Loss”) arising out of or based upon any representation or warranty of the Subscriber contained herein or in any
document furnished by the Subscriber to the Company and/or the Placement Agent in connection herewith being untrue in any material
respect or any breach or failure by the Subscriber to comply with any covenant or agreement made by the Subscriber herein or therein;
and if for any reason (other than a final non-appealable judgment finding any Issuer Indemnified Party liable for losses, claims,
damages, liabilities or expenses for its gross negligence or willful misconduct) the foregoing indemnity is unavailable to an Issuer
Indemnified Party or insufficient to hold an Issuer Indemnified Party harmless, then the Subscriber shall contribute to the amount
paid or payable by an Issuer Indemnified Party as a result of such loss, claim, damage, liability or expense in such proportion
as is appropriate to reflect not only the relative benefits received by the Company or the Placement agent, as applicable, on the
one hand and the Subscriber on the other, but also the relative fault of the Issuer or the Placement Agent, as applicable, on the
one hand and the Subscriber on the other, as well as any relevant equitable considerations; provided, however, that
the Subscriber shall not be liable to indemnify any Issuer Indemnified Parties under this Section or to contribute to the amount
paid or payable by all Issuer Indemnified Parties under this Section in an amount under both such provisions that in the aggregate
exceeds the Subscriber’s aggregate purchase price tendered hereunder.

 

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		II.	REPRESENTATIONS BY AND COVENANTS OF THE COMPANY

 

The Company hereby represents
and warrants to the Subscriber that:

 

2.1      Organization,
Good Standing and Qualification. The Company is a corporation duly organized, validly existing and in good standing under the
laws of the State of Delaware and has full corporate power and authority to own and use its properties and its assets and conduct
its business as currently conducted. Each of the Company’s subsidiaries identified on Schedule 2.1 hereto (the “Subsidiaries”)
is an entity duly organized, validly existing and in good standing under the laws of the jurisdiction of its incorporation with
the requisite corporate power and authority to own and use its properties and assets and to conduct its business as currently conducted.
Neither the Company, nor any of its Subsidiaries is in violation of any of the provisions of their respective articles of incorporation,
by-laws or other organizational or charter documents, including, but not limited to the Charter Documents (as defined below). Each
of the Company and its Subsidiaries is duly qualified to conduct business and is in good standing as a foreign corporation in each
jurisdiction in which the nature of the business conducted or property owned by it makes such qualification necessary, except where
the failure to be so qualified or in good standing, as the case may be, would not result in a direct and/or indirect (i) material
adverse effect on the legality, validity or enforceability of any of the Securities and/or this Agreement, (ii) material adverse
effect on the results of operations, assets, business, condition (financial and other) or prospects of the Company and its Subsidiaries,
taken as a whole, or (iii) material adverse effect on the Company’s ability to perform in any material respect on a timely
basis its obligations under the Transaction Documents (any of (i), (ii) or (iii), a “Material Adverse Effect”).

 

2.2      Capitalization
and Voting Rights. The authorized, issued and outstanding capital stock of the Company is as set forth in Transaction Documents
and all issued and outstanding shares of capital stock of the Company are validly issued, fully paid and nonassessable. Except
as set forth in Transaction Documents hereto, (i) there are no outstanding securities of the Company or any of its Subsidiaries
which contain any preemptive, redemption or similar provisions, nor is any holder of securities of the Company or any Subsidiary
entitled to preemptive or similar rights arising out of any agreement or understanding with the Company or any Subsidiary by virtue
of any of the Transaction Documents, and there are no contracts, commitments, understandings or arrangements by which the Company
or any of its Subsidiaries is or may become bound to redeem a security of the Company or any of its Subsidiaries; (ii) neither
the Company nor any Subsidiary has any stock appreciation rights or "phantom stock" plans or agreements or any similar
plan or agreement; and (iii) except as set forth in Transaction Documents there are no outstanding options, warrants, agreements,
convertible securities, preemptive rights or other rights to subscribe for or to purchase or acquire, any shares of capital stock
of the Company or any Subsidiary or contracts, commitments, understandings, or arrangements by which the Company or any Subsidiary
is or may become bound to issue any shares of capital stock of the Company or any Subsidiary, or securities or rights convertible
or exchangeable into shares of capital stock of the Company or any Subsidiary. Except as set forth in Transaction Documents and
as otherwise required by law, there are no restrictions upon the voting or transfer of any of the shares of capital stock of the
Company pursuant to the Company’s Charter Documents (as defined below) or other governing documents or any agreement or other
instruments to which the Company is a party or by which the Company is bound. All of the issued and outstanding shares of capital
stock of the Company are validly issued, fully paid and nonassessable and the shares of capital stock of the Subsidiaries are owned
by the Company, free and clear of any mortgages, pledges, liens, claims, charges, encumbrances or other restrictions (collectively,
“Encumbrances”). All of such outstanding capital stock has been issued in compliance with applicable federal and state
securities laws. The issuance and sale of the Securities and, upon issuance, the Shares, as contemplated hereby will not obligate
the Company to issue shares of Common Stock or other securities to any other person (other than the Subscriber) and except as set
forth in Transaction Documents will not result in the adjustment of the exercise, conversion, exchange or reset price of any outstanding
security. The Company does not have outstanding stockholder purchase rights or “poison pill” or any similar arrangement
in effect giving any person the right to purchase any equity interest in the Company upon the occurrence of certain events.

 

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2.3      Authorization;
Enforceability. The Company has all corporate right, power and authority to enter into, execute and deliver this Agreement
and each other agreement, document, instrument and certificate to be executed by the Company in connection with the consummation
of the transactions contemplated hereby, including, but not limited to Transaction Documents and to perform fully its obligations
hereunder and thereunder. All corporate action on the part of the Company, its directors and stockholders necessary for the (a)
authorization execution, delivery and performance of this Agreement and the Transaction Documents by the Company; and (b) authorization,
sale, issuance and delivery of the Securities and upon issuance, the Shares contemplated hereby and the performance of the Company’s
obligations under this Agreement and the Transaction Documents has been taken. This Agreement and the Transaction Documents have
been duly executed and delivered by the Company and each constitutes a legal, valid and binding obligation of the Company, enforceable
against the Company in accordance with its respective terms, subject to laws of general application relating to bankruptcy, insolvency
and the relief of debtors and rules of law governing specific performance, injunctive relief or other equitable remedies, and to
limitations of public policy. The Securities are duly authorized and, when issued and paid for in accordance with the applicable
Transaction Documents, will be duly and validly issued, fully paid and nonassessable, free and clear of all Encumbrances other
than restrictions on transfer provided for in the Transaction Documents. The Shares, when issued and paid for in accordance with
the terms of the Transaction Documents, will be validly issued, fully paid and nonassessable, free and clear of all Encumbrances
imposed by the Company other than restrictions on transfer provided for in the Transaction Documents. Subject at all times to the
provisions of Sections 2.4 and 5.12 below, the Company will have reserved a sufficient number of Conversion Shares and Warrant
Shares for issuance upon the conversion of the Series A Preferred Stock and exercise of the Warrants, respectively, free and clear
of all Encumbrances, except for restrictions on transfer set forth in the Transaction Documents or imposed by applicable securities
laws. Except as set forth on Schedule 2.3 hereto, the issuance and sale of the Securities (including the Shares) contemplated
hereby will not give rise to any preemptive rights or rights of first refusal on behalf of any person other than the Subscribers.

 

2.4      The
Charter Amendment or Reverse Stock Split.         As set forth in Section 5.12
of this Agreement, the Company covenants and agrees to obtain Stockholder Approval for the Charter Amendment on or before October
31, 2016 and consummate the Reverse Stock Split on or before October 31, 2016 or the Termination Date of this Offering.

 

2.5      No
Conflict; Governmental Consents.

 

(a)         The
execution and delivery by the Company of this Agreement and the Transaction Documents, the issuance and sale of the Securities
(including, when issued, the Shares) and the consummation of the other transactions contemplated hereby or thereby do not and will
not (i) result in the violation of any law, statute, rule, regulation, order, writ, injunction, judgment or decree of any court
or governmental authority to or by which the Company is bound including without limitation all foreign, federal, state and local
laws applicable to its business and all such laws that affect the environment, except in each case as could not have or reasonably
be expected to result in a Material Adverse Effect, (ii) conflict with or violate any provision of the Company’s Articles
of Incorporation (the “Articles”), as amended or the Bylaws, (and collectively with the Articles, the “Charter
Documents”) of the Company, and (iii) conflict with, or result in a material breach or violation of, any of the terms or
provisions of, or constitute (with or without due notice or lapse of time or both) a default or give to others any rights of termination,
amendment, acceleration or cancellation (with or without due notice, lapse of time or both) under any agreement, credit facility,
lease, loan agreement, mortgage, security agreement, trust indenture or other agreement or instrument to which the Company or any
Subsidiary is a party or by which any of them is bound or to which any of their respective properties or assets is subject, nor
result in the creation or imposition of any Encumbrances upon any of the properties or assets of the Company or any Subsidiary.

 

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(b)        No
approval by the holders of Common Stock, or other equity securities of the Company is required to be obtained by the Company in
connection with the authorization, execution, delivery and performance of this Agreement and the other Transaction Documents or
in connection with the authorization, issue and sale of the Securities and, upon issuance, the Shares, except as has been previously
obtained.

 

(c)         No
consent, approval, authorization or other order of any governmental authority or any other person is required to be obtained by
the Company in connection with the authorization, execution, delivery and performance of this Agreement and the other Transaction
Documents or in connection with the authorization, issue and sale of the Securities and, upon issuance, the Shares, except such
post-sale filings as may be required to be made with the SEC, FINRA and with any state or foreign blue sky or securities regulatory
authority, all of which shall be made when required.

 

2.6      Consents
of Third Parties. No vote, approval or consent of any holder of capital stock of the Company or any other third parties is
required or necessary to be obtained by the Company in connection with the authorization, execution, deliver and performance of
this Agreement and the other Transaction Documents or in connection with the authorization, issue and sale of the Securities and,
upon issuance, the Shares, except as previously obtained, each of which is in full force and effect.

 

2.7      SEC
Reports; Financial Statements. The Company has (a) for the twenty-four (24) months preceding the filing of the Form 10-K (or
such shorter period as the Company was required by law to file such reports) (i) disclosed all material information required to
be publicly disclosed by it on Form 8-K, (ii) filed all reports on Form 10-Q and Form 10-K and (iii) filed all other reports (other
than any Form 8-K) required to be filed by it under the Securities Act and the Exchange Act, including pursuant to Section 13(a)
or 15(d) thereof, and (b) since the filing of the Form 10-K, the Company has filed all reports required to be filed by it under
the Securities Act and Exchange Act (the foregoing materials being collectively referred to herein as the "SEC Reports"
and, together with the Schedules to this Agreement (if any), the "Disclosure Materials") on a timely basis or has timely
filed a valid extension of such time of filing and has filed any such SEC Reports prior to the expiration of any such extension.
As of their respective dates, the SEC Reports complied in all material respects with the requirements of the Exchange Act and the
rules and regulations of the SEC promulgated thereunder, and none of the SEC Reports, when filed, contained any untrue statement
of a material fact or omitted to state a material fact required to be stated therein or necessary in order to make the statements
therein, in light of the circumstances under which they were made, not misleading. The financial statements of the Company included
in the SEC Reports comply in all material respects with applicable accounting requirements and the rules and regulations of the
SEC with respect thereto as in effect at the time of filing. Such financial statements have been prepared in accordance with United
States generally accepted accounting principles (“GAAP”) applied on a consistent basis during the periods involved,
except as may be otherwise specified in such financial statements or the footnotes thereto, and fairly present in all material
respects the financial position of the Company and its consolidated Subsidiaries as of and for the dates thereof and the results
of operations and cash flows for the periods then ended, subject, in the case of unaudited statements, to normal, immaterial, year-end
audit adjustments.

 

2.8      Licenses.
Except as otherwise set forth on the Schedule 2.8, the Company and its Subsidiaries have sufficient licenses, permits and
other governmental authorizations currently required for the conduct of their respective businesses or ownership of properties
and is in all material respects in compliance therewith.

 

    	9

     

    

 

2.9      Litigation.
Except as set forth on the Schedule 2.9, the Company knows of no pending or threatened legal or governmental proceedings
against the Company or any Subsidiary which could materially adversely affect the business, property, financial condition or operations
of the Company and its Subsidiaries, taken as a whole, or which materially and adversely questions the validity of this Agreement
or the other Transaction Documents or the right of the Company to enter into this Agreement and the other Transaction Documents,
or to perform its obligations hereunder and thereunder. Neither the Company nor any Subsidiary is a party or subject to the provisions
of any order, writ, injunction, judgment or decree of any court or government agency or instrumentality which could materially
adversely affect the business, property, financial condition or operations of the Company and its Subsidiaries taken as a whole.
There is no action, suit, proceeding or investigation by the Company or any Subsidiary currently pending in any court or before
any arbitrator or that the Company or any Subsidiary intends to initiate. Neither the Company nor any Subsidiary, nor any director
or officer thereof, is or since the filing of the Form 10-K has been the subject of any action involving a claim of violation of
or liability under federal or state securities laws or a claim of breach of fiduciary duty. There has not been, and to the Company’s
knowledge, there is not pending or contemplated, any investigation by the SEC involving the Company or any current or former director
or officer of the Company.

 

2.10    Compliance.
Except as set forth on Schedule 2.10, neither the Company nor any Subsidiary: (i) is in default under or in violation of
(and no event has occurred that has not been waived that, with notice or lapse of time or both, would result in a default by the
Company or any Subsidiary under), nor has the Company or any Subsidiary received notice of a claim that it is in default under
or that it is in violation of, any indenture, loan or credit agreement or any other agreement or instrument to which it is a party
or by which it or any of its properties is bound (whether or not such default or violation has been waived), (ii) is in violation
of any judgment, decree or order of any court, arbitrator or other governmental authority or (iii) is or has been in violation
of any statute, rule, ordinance or regulation of any governmental authority, including without limitation all foreign, federal,
state and local laws relating to taxes, environmental protection, occupational health and safety, product quality and safety and
employment and labor matters, except in each case as could not have or reasonably be expected to result in a Material Adverse Effect.

 

2.11    Regulatory
Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal,
state, local or foreign regulatory authorities necessary to conduct their respective businesses, except where the failure to possess
such permits could not reasonably be expected to result in a Material Adverse Effect (“Material Permits”), and neither
the Company nor any Subsidiary has received any notice of proceedings relating to the revocation or modification of any Material
Permit.

 

2.12    Disclosure.
The information set forth in the Transaction Documents as of the date hereof and as of the date of each Closing contains no untrue
statement of a material fact nor omits to state a material fact necessary in order to make the statements contained therein, in
light of the circumstances under which they were made, not misleading.

 

2.13    Investment
Company. The Company is not an “investment company” within the meaning of such term under the Investment Company
Act of 1940, as amended, and the rules and regulations of the SEC thereunder.

 

    	10

     

    

 

2.14    Brokers.
Except for the Placement Agent and as set forth on Schedule 2.14, neither the Company nor any of the Company's officers,
directors, employees or stockholders has employed or engaged any broker or finder in connection with the transactions contemplated
by this Agreement and no fee or other compensation is or will be due and owing to any broker, finder, underwriter, placement agent
or similar person in connection with the transactions contemplated by this Agreement. The Company is not party to any agreement,
arrangement or understanding whereby any person has an exclusive right to raise funds and/or place or purchase any debt or equity
securities for or on behalf of the Company.

 

2.15    Intellectual
Property; Employees.

 

(a)         The
Company owns or possesses sufficient legal rights to all patents, trademarks, service marks, trade names, copyrights, trade secrets,
licenses, information and other proprietary rights and processes necessary for its business as now conducted and as presently proposed
to be conducted, without any known infringement of the rights of others as set forth on Schedule 2.15 and which the failure
to so have could have a Material Adverse Effect (collectively, the “Intellectual Property Rights”). Except as disclosed
on Schedule 2.15 or the SEC Reports, there are no material outstanding options, licenses or agreements of any kind relating
to the Intellectual Property Rights, nor is the Company bound by or a party to any material options, licenses or agreements of
any kind with respect to the patents, trademarks, service marks, trade names, copyrights, trade secrets, licenses, information
and other proprietary rights and processes of any other person or entity other than such licenses or agreements arising from the
purchase of “off the shelf” or standard products. The Company has not received any written communications alleging
that the Company has violated or, by conducting its business as presently proposed to be conducted, would violate any Intellectual
Property Rights of any other person or entity. The Company and its Subsidiaries have taken reasonable security measures to protect
the secrecy, confidentiality and value of all of their intellectual properties, except where failure to do so could not, individually
or in the aggregate, reasonably be expected to have a Material Adverse Effect

 

(b)         Except
as set forth on Schedule 2.15, the Company is not aware that any of its employees is obligated under any contract (including
licenses, covenants or commitments of any nature) or other agreement, or subject to any judgment, decree or order of any court
or administrative agency, that would interfere with their duties to the Company or that would conflict with the Company’s
business as presently conducted.

 

(c)         Neither
the execution nor delivery of this Agreement, nor the carrying on of the Company’s business by the employees of the Company,
nor the conduct of the Company’s business as presently conducted, will, to the Company’s knowledge, conflict with or
result in a breach of the terms, conditions or provisions of, or constitute a default under, any contract, covenant or instrument
under which any employee is now obligated.

 

(d)         To
the Company’s knowledge, no employee of the Company, nor any consultant with whom the Company has contracted, is in violation
of any term of any employment contract, proprietary information agreement or any other agreement and to the Company’s knowledge
the continued employment by the Company of its present employees, and the performance of the Company’s contracts with its
independent contractors, will not result in any such violation. The Company has not received any written notice alleging that any
such violation has occurred. Except as set forth on Schedule 2.15, no employee of the Company has been granted the right
to continued employment by the Company or to any compensation following termination of employment with the Company except for any
of the same which would not have a Material Adverse Effect on the business of the Company. The Company is not aware that any officer,
key employee or group of employees intends to terminate his, her or their employment with the Company, nor does the Company have
a present intention to terminate the employment of any officer, key employee or group of employees.

 

    	11

     

    

 

2.16    Title
to Properties and Assets; Liens, Etc. Except as set forth on Schedule 2.16, the Company has good and marketable title
to its properties and assets, including the properties and assets reflected in the most recent balance sheet included in the Company’s
financial statements, and good title to its leasehold estates, in each case subject to no Encumbrances, other than (a) those resulting
from taxes which have not yet become delinquent; and (b) Encumbrances which do not materially detract from the value of the property
subject thereto or materially impair the operations of the Company; and (c) those that have otherwise arisen in the ordinary course
of business, none of which are material. Except as set forth in Schedule 2.16, the Company is in compliance with all material
terms of each lease to which it is a party or is otherwise bound.

 

2.17    Obligations
to Related Parties. Except as set forth on in the Transaction Documents, there are no obligations of the Company to
officers, directors, stockholders, or employees of the Company other than (a) for payment of salary or other compensation for services
rendered, (b) reimbursement for reasonable expenses incurred on behalf of the Company and (c) for other standard employee benefits
made generally available to all employees (including stock option agreements outstanding under any stock option plan approved by
the Board of Directors of the Company). Except as set forth in the Transaction Documents, none of the officers or directors of
the Company and, to the Company’s knowledge, none of the employees of the Company is presently a party to any transaction
with the Company or any Subsidiary (other than as holders of stock options and/or warrants, and for services as employees, officers
and directors), including any contract, agreement or other arrangement providing for the furnishing of services to or by, providing
for rental of real or personal property to or from, or otherwise requiring payments to or from any officer, director or such employee
or, to the Company’s knowledge, any entity in which any officer, director, or any such employee has a substantial interest
or is an officer, director, trustee or partner.

 

2.18    Material
Changes. Except as set forth in the Transaction Documents, since the date of the latest audited financial statements included
within the SEC Reports (i) there has been no event, occurrence or development that has had or that could reasonably be expected
to result in a Material Adverse Effect, (ii) the Company has not incurred any liabilities (contingent or otherwise) other than
(A) trade payables, accrued expenses and other liabilities incurred in the ordinary course of business consistent with past practice
and (B) liabilities not required to be reflected in the Company's financial statements pursuant to generally accepted accounting
principles or required to be disclosed in filings made with the SEC, (iii) the Company has not altered its method of accounting
or the identity of its auditors, (iv) the Company has not declared or made any dividend or distribution of cash or other property
to its stockholders or purchased, redeemed or made any agreements to purchase or redeem any shares of its capital stock, and (v)
the Company has not issued any equity securities to any officer, director or affiliate, except pursuant to existing Company stock
option plans. The Company does not have pending before the SEC any request for confidential treatment of information.

 

2.19    Sarbanes-Oxley.
The Company is in compliance with all effective requirements of the Sarbanes-Oxley Act of 2002, as amended, and the rules and regulations
thereunder, that are applicable to it, except where such noncompliance could not have or reasonably be expected to result in a
Material Adverse Effect.

 

2.20    No
General Solicitation. None of the Company, its Subsidiaries, any of their affiliates, and any person acting on their
behalf, has engaged in any form of general solicitation or general advertising (within the meaning of Regulation D under the
Securities Act) in connection with the offer or sale of the Securities.

 

    	12

     

    

 

2.21    No
Integrated Offering. Assuming the accuracy of the Subscriber representations and warranties set forth in Article I hereunder,
none of the Company, its Subsidiaries, any of their affiliates, and any person acting on their behalf has, directly or indirectly,
made any offers or sales of any security or solicited any offers to buy any security, under circumstances that would require registration
of any of the Securities under the Securities Act or that is likely to cause this offering of the Securities to be integrated with
prior offerings by the Company for purposes of the Securities Act or any applicable stockholder approval provisions, including
without limitation, under the rules and regulations of any exchange or automated quotation system on which any of the securities
of the Company are listed or designated. Except as set forth in the Transaction Documents or on Schedule 2.21, none of the
Company, its Subsidiaries, their affiliates and any person acting on their behalf, have taken any action or steps referred to in
the preceding sentence that would require registration of any of the Securities under the Securities Act or cause the offering
of the Securities to be integrated with other offerings.

 

2.22    Application
of Takeover Protections. The Company has taken all necessary action, if any, in order to render inapplicable any control share
acquisition, business combination, poison pill (including any distribution under a rights agreement) or other similar anti-takeover
provision under the Company's Charter Documents or the laws of its state of incorporation that is or could become applicable to
the Subscriber as a result of the Subscriber and the Company fulfilling their obligations or exercising their rights under this
Agreement, including, without limitation, the Company's issuance of the Securities and the Subscriber' ownership of the Securities.

 

2.23    Taxes.
Each of the Company and its subsidiaries has filed all U.S. federal, state, local and foreign tax returns which are required to
be filed by each of them and all such returns are true and correct in all material respects. The Company and each subsidiary has
paid all taxes whether or not shown on such returns or pursuant to any assessments received by any of them or by which any of them
are obligated to withhold from amounts owing to any employee, creditor or third party. The Company and each subsidiary has properly
accrued all taxes required to be accrued and/or paid, except where the failure to accrue would not have a Material Adverse Effect.
To the knowledge of the Company, none of the tax returns of the Company nor any of its subsidiaries is currently being audited
by any state, local or federal authorities. Neither the Company nor any subsidiary has waived any statute of limitations with respect
to taxes or agreed to any extension of time with respect to any tax assessment or deficiency. The Company has set aside on its
books adequate provision for the payment of any unpaid taxes.

 

2.24    Registration
Rights. Except as set forth on Schedule 2.24, no person has any right to cause the Company to effect the registration
under the Securities Act of any securities of the Company.

 

2.25    Listing
and Maintenance Requirements. The Common Stock is registered pursuant to Section 12(b) or 12(g) of the Exchange Act, and the
Company has taken no action designed to, or which to its knowledge is likely to have the effect of, terminating the registration
of the Common Stock under the Exchange Act nor has the Company received any notification that the SEC is contemplating terminating
such registration. The Company has not, in the 12 months preceding the date hereof, received notice from any trading market on
which the Common Stock is or has been listed or quoted to the effect that the Company is not in compliance with the listing or
maintenance requirements of such trading market. The Company is, and has no reason to believe that it will not in the foreseeable
future continue to be, in compliance with all such listing and maintenance requirements

 

    	13

     

    

 

2.26    Disclosure.
All disclosure furnished by or on behalf of the Company to the Subscriber in the Transaction Documents regarding the Company, its
business and the transactions contemplated hereby, including the Disclosure Schedules to this Agreement, is true and correct and
does not contain any untrue statement of a material fact or omit to state any material fact necessary in order to make the statements
made therein, in light of the circumstances under which they were made, not misleading.

 

2.27    Seniority.
Except for the issuance to a lender on September 7, 2016 of a $725,000 principal amount note due October 15, 2016 and secured by
a lien on the Company’s accounts receivable and inventory, the proceeds for which were used to retire a prior maturing note
(the “Refinancing Note”), no indebtedness or other claim against the Company is senior to the Series A Preferred Stock
in right of payment, whether with respect to interest or upon liquidation or dissolution, or otherwise, other than indebtedness
secured by purchase money security interests (which is senior only as to underlying assets covered thereby) and capital lease obligations
(which is senior only as to the property covered thereby).

 

2.28    Private
Placement. Assuming the accuracy of the Subscribers’ representations and warranties set forth in Section 1, no registration
under the Securities Act is required for the offer and sale of the Securities by the Company to the Subscriber as contemplated
hereby.

 

		III.	TERMS OF SUBSCRIPTION

 

3.1      The
minimum purchase that may be made by any prospective investor shall be $10,000. Subscriptions for investment below the minimum
investment may be accepted at the discretion of the Placement Agent and the Company. The Company and the Placement Agent each reserve
the right to reject any subscription made hereby, in whole or in part, in its sole discretion. The Company’s agreement with
each Subscriber is a separate agreement and the sale of the Securities to each Subscriber is a separate sale.

 

3.2      All
funds shall be deposited in the account identified in Section 1.1 hereof.

 

3.3      Certificates
representing the Series A Preferred Stock and the Warrants purchased by the Subscriber pursuant to this Agreement will be prepared
for delivery to the Subscriber as soon as practicable (but in no event more than five (5) Trading Days) following the Closing at
which such purchase takes place. The Subscriber hereby authorizes and directs the Company to deliver the certificates representing
the Series A Preferred Stock and the Warrants purchased by the Subscriber pursuant to this Agreement directly to the Placement
Agent unless otherwise indicated on the signature page hereto.

 

		IV.	CONDITIONS TO OBLIGATIONS OF THE SUBSCRIBER

 

4.1      The
Subscriber’s obligation to purchase the Securities at the Closing at which such purchase is to be consummated is subject
to the fulfillment on or prior to such Closing of the following conditions, which conditions may be waived at the option of each
Subscriber to the extent permitted by law:

 

(a)         Representations
and Warranties; Covenants. The representations and warranties made by the Company in Section 2 hereof qualified as to materiality
shall be true and correct as of the Initial Closing at all times prior to and on the Closing Date, except (i) to the extent any
such representation or warranty expressly speaks as of an earlier date, in which case such representation or warranty shall be
true and correct as of such earlier date, and, (ii) the representations and warranties made by the Company in Section 2 hereof
not qualified as to materiality shall be true and correct in all material respects at all times prior to and on the Closing Date,
except to the extent any such representation or warranty expressly speaks as of an earlier date, in which case such representation
or warranty shall be true and correct in all material respects as of such earlier date; provided however, that notwithstanding
the foregoing, the Company shall only be required to update the Disclosure Schedules by the delivery to the Subscribers by the
Company of an amended Disclosure Schedule with respect to any information that is of a material nature as of such proposed Closing
Date. All covenants, agreements and conditions contained in this Agreement to be performed by the Company on or prior to the date
of such Closing shall have been performed or complied with in all material respects.

 

    	14

     

    

 

(b)         No
Legal Order Pending. There shall not then be in effect any legal or other order enjoining or restraining the transactions contemplated
by this Agreement.

 

(c)         No
Law Prohibiting or Restricting Such Sale. There shall not be in effect any law, rule or regulation prohibiting or restricting
such sale or requiring any consent or approval of any person, which shall not have been obtained, to issue the Securities (except
as otherwise provided in this Agreement).

 

(d)         Required
Consents. The Company shall have obtained any and all consents, permits, approvals, registrations and waivers necessary or
appropriate for consummation of the purchase and sale of the Securities and the consummation of the other transactions contemplated
by the Transaction Documents, all of which shall be in full force and effect.

 

(e)         Adverse
Changes. Since the date of execution of this Agreement, no event or series of events shall have occurred that reasonably could
have or result in a Material Adverse Effect.

 

(f)          No
Suspensions of Trading in Common Stock; Listing. Trading in the Common Stock shall not have been suspended by the SEC or any
trading market (except for any suspensions of trading of not more than one trading day solely to permit dissemination of material
information regarding the Company) at any time since the date of execution of this Agreement, and the Common Stock shall have been
at all times since such date listed for trading on a trading market.

 

(g)         Blue
Sky. The Company shall have completed qualification for the Securities and the Shares under applicable Blue Sky laws.

 

(h)         Legal
Opinion. The Company’s corporate counsel shall have delivered a legal opinion addressed to the Subscribers in a form
reasonably acceptable to the Placement Agent.

 

(i)          Disclosure
Schedules. The Company shall have delivered to the Subscriber a copy of its Disclosure Schedules (or amended Disclosure Schedules)
qualifying any of the representations and warranties contained in Section 2 as of the applicable Closing.

 

		V.	COVENANTS OF THE COMPANY

 

5.1      Transfer
Restrictions.

 

(a)         The
Securities may only be disposed of in compliance with state and federal securities laws. In connection with any transfer of Securities
other than pursuant to an effective registration statement or Rule 144 promulgated under the Securities Act, to the Company or
to an affiliate of a Subscriber or in connection with, the Company may require the transferor thereof to provide to the Company
an opinion of counsel selected by the transferor and reasonably acceptable to the Company, the form and substance of which opinion
shall be reasonably satisfactory to the Company, to the effect that such transfer does not require registration of such transferred
Securities under the Securities Act. As a condition of transfer, any such transferee shall agree in writing to be bound by the
terms of this Agreement, and shall have the rights of a Subscriber under this Agreement.

 

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(b)         The
Subscriber agrees to the imprinting, so long as is required by this Section 5.1, of a legend on any of the Securities, including
the Shares, substantially in the following form:

 

[NEITHER] THIS SECURITY [NOR THE SECURITIES
INTO WHICH THIS SECURITY IS [EXERCISABLE] [CONVERTIBLE]] HAS [NOT] BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION
OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS
AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION
STATEMENT UNDER THE SECURITIES ACT OR PURSUANT TO AN AVAILABLE EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION
REQUIREMENTS OF THE SECURITIES ACT AND IN ACCORDANCE WITH APPLICABLE STATE SECURITIES LAWS AS EVIDENCED BY A LEGAL OPINION OF COUNSEL
TO THE TRANSFEROR TO SUCH EFFECT, THE SUBSTANCE OF WHICH SHALL BE REASONABLY ACCEPTABLE TO THE COMPANY. THIS SECURITY [AND THE
SECURITIES ISSUABLE UPON [EXERCISE] [CONVERSION] OF THIS SECURITY] MAY BE PLEDGED IN CONNECTION WITH A BONA FIDE MARGIN ACCOUNT
OR OTHER LOAN SECURED BY SUCH SECURITIES.

 

(c)         The
Subscriber understands that prior to September 2, 2011, the Company was a “shell company” as defined in Rule 12b-2
under the Securities Exchange Act of 1934, as amended, (the “Exchange Act”). Pursuant to Rule 144(i), securities issued
by a current or former shell company (that is, the Securities and the Shares) that otherwise meet the holding period and other
requirements of Rule 144 nevertheless cannot be sold in reliance on Rule 144 unless at the time of a proposed sale pursuant to
Rule 144 the Company is subject to the reporting requirements of Section 13 or 15(d) of the Exchange Act and has filed all reports
and other materials required to be filed by Section 13 or 15(d) of the Exchange Act, as applicable, during the preceding 12 months
(or for such shorter period that the issuer was required to file such reports and materials), other than Form 8-K reports. As a
result, the restrictive legends on certificates for the Securities or the Shares cannot be removed except in connection with an
actual sale meeting the foregoing requirements or pursuant to an effective registration statement.

 

(d)         Certificates
evidencing the Shares shall not contain any legend (including the legend set forth in Section 4.1(b) hereof): (i) while a registration
statement covering the resale of such security is effective under the Securities Act, or (ii) following any sale of such Shares
pursuant to Rule 144, or (iii) if such legend is not required under applicable requirements of the Securities Act (including judicial
interpretations and pronouncements issued by the staff of the SEC). The Company shall cause its counsel, at the Company’s
expense, to issue a legal opinion to the Company’s transfer agent promptly (but in no event later than the requisite share
delivery date set forth in the Series A Preferred Stock and the Warrants) if required by the Company’s transfer to effect
the removal of the legend hereunder.

 

5.2      Listing
of Securities. The Company agrees, (i) if the Company applies to have the Common Stock traded on any other trading market,
it will include in such application the shares of Common Stock and Shares, and will take such other action as is necessary or desirable
to cause the shares of Common Stock and Shares to be listed on such other trading market as promptly as possible, and (ii) it will
take all action reasonably necessary to continue the listing and trading of its Common Stock on a trading market and will comply
in all material respects with the Company’s reporting, filing and other obligations under the bylaws or rules of the trading
market.

 

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5.3      Reservation
of Shares. Subject to Stockholder Approval (as defined in Section 5.12 of this Agreement), , at all times while the Series
A Preferred Stock and Warrants are outstanding, maintain a reserve from its duly authorized shares of Common Stock of a number
of shares of Common Stock sufficient to allow for the issuance of the Shares.

 

5.4      Replacement
of Securities. If any certificate or instrument evidencing any Securities or the Shares is mutilated, lost, stolen or destroyed,
the Company shall issue or cause to be issued in exchange and substitution for and upon cancellation thereof, or in lieu of and
substitution therefor, a new certificate or instrument, but only upon receipt of evidence reasonably satisfactory to the Company
of such loss, theft or destruction and customary and reasonable indemnity, if requested. The applicants for a new certificate or
instrument under such circumstances shall also pay any reasonable third-party costs associated with the issuance of such replacement
securities. If a replacement certificate or instrument evidencing any securities is requested due to a mutilation thereof, the
Company may require delivery of such mutilated certificate or instrument as a condition precedent to any issuance of a replacement.

 

5.5      Furnishing
of Information. Until the time that no Subscriber owns Securities, the Company covenants to maintain the registration of the
Common Stock under Section 12(b) or 12(g) of the Exchange Act and to timely file (or obtain extensions in respect thereof and file
within the applicable grace period) all reports required to be filed by the Company after the date hereof pursuant to the Exchange
Act. As long as Subscriber owns Securities, if the Company is not required to file reports pursuant to the Exchange Act, it will
prepare and furnish to Subscriber and make publicly available in accordance with Rule 144(c) such information as is required for
the Subscribers to sell the Securities under Rule 144. The Company further covenants that it will take such further action as any
holder of Securities may reasonably request, to the extent required from time to time to enable such person to sell such Securities
without registration under the Securities Act within the requirements of the exemption provided by Rule 144.

 

5.6      Securities
Laws; Publicity. Unless otherwise required by applicable law, the Company shall, by 8:30 a.m. (New York City time) on the fourth
trading day immediately following the first and last Closings hereunder, issue a Current Report on Form 8-K disclosing the material
terms of the transactions contemplated hereby and including the Transaction Documents as exhibits thereto to the extent required
by law. The Company shall not publicly disclose the name of Subscriber, or include the name of any Subscriber in any filing with
the SEC or any regulatory agency or trading market, without the prior written consent of Subscriber, except: (a) as required by
federal securities law in connection with the filing of final Transaction Documents (including signature pages thereto) with the
SEC and (b) to the extent such disclosure is required by law, in which case the Company shall provide the Subscriber with prior
notice of such disclosure permitted under this clause (b).

 

5.7      Form
D; Blue Sky Filings. The Company agrees to timely file a Form D with respect to the Securities as required under Regulation
D promulgated under the Securities Act and to provide a copy thereof, promptly upon request of the Subscriber. The Company shall
take such action as the Company shall reasonably determine is necessary in order to obtain an exemption for, or to qualify the
Securities for, sale to the Subscriber at the Closing under applicable securities or “Blue Sky” laws of the states
of the United States, and shall provide evidence of such actions promptly upon request of any Subscriber.

 

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5.8      Equal
Treatment of Subscribers. No consideration (including any modification of any Transaction Document) shall be offered or paid
to any person to amend or consent to a waiver or modification of any provision of any of the Transaction Documents unless the same
consideration is also offered to all of the parties to the Transaction Documents.

 

5.9      Indemnification. 

 

(a)          The
Company agrees to indemnify and hold harmless the Subscriber, its affiliates and their respective officers, directors, employees,
agents and controlling persons (collectively, the “Subscriber Indemnified Parties”) from and against any and
all loss, liability, damage or deficiency suffered or incurred by any Indemnified Party by reason of any misrepresentation or breach
of warranty by the Company or, after any applicable notice and/or cure periods, nonfulfillment of any covenant or agreement to
be performed or complied with by the Company, in each case contained in this Agreement or any of the other Transaction Documents;
and will promptly reimburse the Subscriber Indemnified Parties for all expenses (including reasonable fees and expenses of legal
counsel) as incurred in connection with the investigation of, preparation for or defense of any pending or threatened claim related
to or arising in any manner out of any of the foregoing, or any action or proceeding arising therefrom (collectively, “Proceedings”),
whether or not such Subscriber Indemnified Party is a formal party to any such Proceeding.

 

(b)         If
for any reason (other than a final non-appealable judgment finding any Subscriber Indemnified Party liable for losses, claims,
damages, liabilities or expenses for its gross negligence or willful misconduct) the foregoing indemnity is unavailable to an Subscriber
Indemnified Party or insufficient to hold an Subscriber Indemnified Party harmless, then the Company shall contribute to the amount
paid or payable by a Subscriber Indemnified Party as a result of such loss, claim, damage, liability or expense in such proportion
as is appropriate to reflect not only the relative benefits received by the Company on the one hand and the Subscriber on the other,
but also the relative fault of the Company or the Placement Agent, as applicable, on the one hand and the Subscriber on the other,
as well as any relevant equitable considerations.

 

(c)         Notwithstanding the foregoing, the Company shall not be liable to indemnify any Subscriber Indemnified Parties
under Section 5.9(a) or to contribute to the amount paid or payable by all Subscriber Indemnified Parties under Section 5.9(b)
in an amount under both such Sections that in the aggregate exceeds the Subscriber’s aggregate purchase price tendered hereunder.

 

5.10    Non-Public
Information. Except with respect to the material terms and conditions of the transactions contemplated by the Transaction Documents,
the Company covenants and agrees that neither it, nor any other person acting on its behalf, will provide Subscriber or its agents
or counsel with any information that the Company believes constitutes material non-public information, unless prior thereto Subscriber
shall have executed a written agreement regarding the confidentiality and use of such information. The Company understands and
confirms that Subscriber shall be relying on the foregoing covenant in effecting transactions in securities of the Company.

 

    	18

     

    

 

5.11    Use
of Proceeds. Except as set forth on Schedule 5.11 attached hereto, the Company shall use the net proceeds from the sale
of the Securities hereunder for working capital purposes and shall not use such proceeds for: (a) the satisfaction of any portion
of the Company’s debt (other than payment of trade payables in the ordinary course of the Company’s business and prior
practices), (b) the redemption of any Common Stock or Common Stock equivalents or (c) the settlement of any outstanding litigation.

 

5.12    Stockholder
Approval and Reverse Stock Split.  

 

(a)         The
Company has filed a definitive proxy statement with the SEC on September 23, 2016 (the “Proxy Statement”) and
shall use its best efforts to obtain, on or before October 31, 2016, such approvals of the Company’s stockholders as may
be required to issue all of the shares of Common Stock issuable upon conversion or exercise of, or otherwise with respect to, the
Series A Preferred Stock and the Warrants in accordance with Delaware law and any applicable rules or regulations of any national
securities exchange and/or any over-the-counter market on which the Company’s common stock is listed and/or quoted, th an
increase in the Company’s authorized capital (the “Stockholder Approval”).   If the Company
shall fail for any reason to obtain Stockholder Approval and file the Charter Amendment with the Secretary of State of the State
of Delaware on or prior to October 31, 2016 (a “Charter Amendment Failure”) then, in addition to such
Subscriber’s other available remedies, the Company shall pay to a Subscriber, in cash, as partial liquidated damages and
not as a penalty, by reason of any such delay in or reduction of its ability to sell the Securities, an amount in cash equal to
one percent (1.0%) of the aggregate Subscription Amount of such Subscriber’s Securities on the day of a Charter Amendment
Failure and on every thirtieth (30th) day (pro rated for periods totaling less than thirty days) thereafter until the
date such Charter Amendment Failure is cured. The parties agree that the maximum aggregate liquidated damages payable to an Subscriber
under this Section shall be 8% of the aggregate Purchase Price paid by such Subscriber pursuant to this Agreement. The payments
to which a Purchaser shall be entitled pursuant to this Section are referred to herein as “Charter Amendment Failure Payments.”
Charter Amendment Failure Payments shall be paid on the earlier of (i) the last day of the calendar month during which such Charter
Amendment Failure Payments are incurred and (ii) the third (3rd) Business Day after the event or failure giving rise to the Charter
Amendment Failure Payments is cured. If the Company fails to pay any partial liquidated damages pursuant to this Section in full
within seven days after the date payable, the Company will pay interest thereon at a rate of 18% per annum (or such lesser maximum
amount that is permitted to be paid by applicable law) to the Subscriber, accruing daily from the date such partial liquidated
damages are due until such amounts, plus all such interest thereon, are paid in full. Nothing herein shall limit such Purchaser’s
right to pursue actual damages for the Public Information Failure, and such Purchaser shall have the right to pursue all remedies
available to it at law or in equity including, without limitation, a decree of specific performance and/or injunctive relief.

 

(c)         In
addition, the Company covenants and agrees that on or prior to the Termination Date, the Company shall consummate and obtain all
necessary regulatory approvals (including FINRA) for a 1-for-25 reverse stock split of its outstanding Common Stock, which reverse
stock split was approved on December 1, 2015 by the requisite majority of Company stockholders and the Company’s board of
directors was authorized to effect such reverse stock split at a ratio determined by them within a range of between 1-for-15 and
1-for-25 (the “Authorized Reverse Stock Split”).The Company represents and warrants that its Board of Directors
has approved the proposals contemplated by this Section.

 

    	19

     

    

 

		VI.	MISCELLANEOUS

 

6.1      Any
and all notices or other communications or deliveries required or permitted to be provided hereunder shall be in writing and shall
be deemed given and effective on the earliest of: (a) the date of transmission, if such notice or communication is delivered via
facsimile or by electronic communication at or prior to 5:30 p.m. (New York City time) on a day in which the New York Stock Exchange
is open for trading (a “Trading Day”), (b) the next Trading Day after the date of transmission, if such notice or communication
is delivered via facsimile or electronic communication on a day that is not a Trading Day or later than 5:30 p.m. (New York City
time) on any Trading Day, (c) the second (2nd) Trading Day following the date of mailing, if sent by U.S. nationally
recognized overnight courier service or (d) upon actual receipt by the party to whom such notice is required to be given. The address
for such notices and communications shall be addressed as follows:

 

if to the Company,
to it at:

 

Protea Biosciences Group, Inc.

1311 Pineview Drive, Suite 501

Morgantown, WV 26505

Attn: Stephen C. Turner, CEO

 

With a copy to (which shall not constitute notice):

 

CKR Law LLP

1330 Avenue of the Americas, 14th Floor

New York, NY 10019

Attn: Stephen A. Weiss, Esq.

 

if to the Subscriber, to the Subscriber’s
address indicated on the signature page of this Agreement.

 

With a copy to (which shall not constitute notice):

 

Sichenzia Ross Friedman Ference LLP

61 Broadway, 32nd Floor

New York, NY 10006

Attn: Richard A. Friedman, Esq.

 

if to the Escrow Agent, to it at:

 

Signature Bank

261 Madison Ave.

New York, NY 10016

Attn: Cliff Broder, Group
Director and Senior Vice President

Fax: 646-822-1359

 

6.2      Except
as otherwise provided herein, this Agreement shall not be changed, modified or amended except by a writing signed by the parties
to be charged, and this Agreement may not be discharged except by performance in accordance with its terms or by a writing signed
by the party to be charged. No waiver of any default with respect to any provision, condition or requirement of this Agreement
shall be deemed to be a continuing waiver in the future or a waiver of any subsequent default or a waiver of any other provision,
condition or requirement hereof, nor shall any delay or omission of any party to exercise any right hereunder in any manner impair
the exercise of any such right.

 

    	20

     

    

 

6.3      This
Agreement shall be binding upon and inure to the benefit of the parties hereto and to their respective heirs, legal representatives,
successors and assigns. The Company may not assign this Agreement or any rights or obligations hereunder without the prior written
consent of Subscriber (other than by merger). Subscriber may assign any or all of its rights under this Agreement to any person
to whom Subscriber assigns or transfers any Securities, provided that such transferee agrees in writing to be bound, with respect
to the transferred Securities, by the provisions of the Transaction Documents

 

6.4      The
Transaction Documents, together with the exhibits and schedules thereto, contain the entire understanding of the parties with respect
to the subject matter hereof and supersede all prior agreements and understandings, oral or written, with respect to such matters,
which the parties acknowledge have been merged into such documents, exhibits and schedules.

 

6.5      Upon
the execution and delivery of this Agreement by the Subscriber and the Company, this Agreement shall become a binding obligation
of the Subscriber with respect to the purchase of Securities as herein provided, subject, however, to the right hereby reserved
by the Company to enter into the same agreements with other Subscriber and to reject any subscription, in whole or in part, provided
the Company returns to Subscriber any funds paid by Subscriber with respect to such rejected subscription or portion thereof, without
interest or deduction.

 

6.6      All
questions concerning the construction, validity, enforcement and interpretation of the Transaction Documents shall be governed
by and construed and enforced in accordance with the internal laws of the State of New York, without regard to the principles of
conflicts of law thereof. Each party agrees that all legal proceedings concerning the interpretations, enforcement and defense
of the transactions contemplated by this Agreement and any other Transaction Documents (whether brought against a party hereto
or its respective affiliates, directors, officers, shareholders, employees or agents) shall be commenced exclusively in the state
and federal courts sitting in the City of New York. Each party hereby irrevocably submits to the exclusive jurisdiction of the
state and federal courts sitting in the City of New York, borough of Manhattan for the adjudication of any dispute hereunder or
in connection herewith or with any transaction contemplated hereby or discussed herein (including with respect to the enforcement
of any of the Transaction Documents), and hereby irrevocably waives, and agrees not to assert in any suit, action or proceeding,
any claim that it is not personally subject to the jurisdiction of any such court, that such suit, action or proceeding is improper
or is an inconvenient venue for such proceeding.

 

6.7      In
order to discourage frivolous claims the parties agree that unless a claimant in any proceeding arising out of this Agreement succeeds
in establishing his claim and recovering a judgment against another party (regardless of whether such claimant succeeds against
one of the other parties to the action), then the other party shall be entitled to recover from such claimant all of its/their
reasonable legal costs and expenses relating to such proceeding and/or incurred in preparation therefor.

 

6.8      The
holding of any provision of this Agreement to be invalid or unenforceable by a court of competent jurisdiction shall not affect
any other provision of this Agreement, which shall remain in full force and effect. If any provision of this Agreement shall be
declared by a court of competent jurisdiction to be invalid, illegal or incapable of being enforced in whole or in part, such provision
shall be interpreted so as to remain enforceable to the maximum extent permissible consistent with applicable law and the remaining
conditions and provisions or portions thereof shall nevertheless remain in full force and effect and enforceable to the extent
they are valid, legal and enforceable, and no provisions shall be deemed dependent upon any other covenant or provision unless
so expressed herein.

 

    	21

     

    

 

6.9      It
is agreed that a waiver by either party of a breach of any provision of this Agreement shall not operate, or be construed, as a
waiver of any subsequent breach by that same party.

 

6.10    The
Company agrees to execute and deliver all such further documents, agreements and instruments and take such other and further action
as may be necessary or appropriate to carry out the purposes and intent of this Agreement.

 

6.11    This
Agreement may be executed in two or more counterparts each of which shall be deemed an original, but all of which shall together
constitute one and the same instrument. In the event that any signature is delivered by facsimile transmission or by e-mail delivery
of a “.pdf” format data file, such signature shall create a valid and binding obligation of the party executing (or
on whose behalf such signature is executed) with the same force and effect as if such facsimile or “.pdf” signature
page were an original thereof.

 

6.12    Nothing
in this Agreement shall create or be deemed to create any rights in any person or entity not a party to this Agreement.

 

6.13    In
addition to being entitled to exercise all rights provided herein or granted by law, including recovery of damages, the Subscriber
and the Company will be entitled to specific performance under this Agreement. The parties agree that monetary damages may not
be adequate compensation for any loss incurred by reason of any breach of obligations described in the foregoing sentence and hereby
agrees to waive in any action for specific performance of any such obligation the defense that a remedy at law would be adequate.

 

6.14    Acknowledgment Regarding Subscriber’s Trading Activity. The Company further understands and acknowledges that (a)
Subscriber may engage in hedging activities at various times during the period that the Securities are outstanding, including,
without limitation, during the periods that the value of the Shares deliverable with respect to Securities are being determined,
and (b) such hedging activities (if any) could reduce the value of the existing stockholders' equity interests in the Company at
and after the time that the hedging activities are being conducted.  The Company acknowledges that such aforementioned hedging
activities do not constitute a breach of any of the Transaction Documents.

 

    	22

     

    

 

To subscribe for the Series A Preferred Stock
and Warrants 

to Purchase Shares of Common Stock in the
private offering of

 

PROTEA BIOSCIENCES GROUP, INC.

 

		1.	Date and Fill the (a) the number of Units of the Securities you are purchasing (a minimum
of one full Unit for $10,000), and (b) the total Purchase Price for the Units, equal to $10,000 multiplied by the total number
of Units of Securities being subscribed for.

		2.	Complete and Sign the Signature Page included in this Subscription Agreement.

		3.	Initial the Accredited Investor Certification attached to this Subscription Agreement.

		4.	Complete and Sign the Signature Page attached to this Subscription Agreement.

 

NOTICE: Please note that by executing
this Subscription Agreement, you will be deemed to have executed the Registration Rights Agreement and have agreed to the terms
of the Series A Preferred Stock and each of the Class A Warrants and the Class B Warrants (collectively the “Transaction
Documents”), each of which are attached to the Subscription Agreement, and will be treated for all purposes as if you did
sign and agree to, as applicable, each such Transaction Document even though you may not have physically signed the signature pages
to such documents.

		5.	Complete and Sign the Selling Stockholder Notice and Questionnaire attached hereto as Appendix
A.

		6.	Complete and Return the attached Investor Questionnaire and, if applicable, Wire Transfer
Authorization attached to this Subscription Agreement.

		6.	Return all forms to your Account Executive and then
send all signed original documents with a check (if applicable) to:

 

Laidlaw & Company
(UK) Ltd.

Attn: Investment Banking

546 Fifth Avenue, 5th
Floor

New York, NY 10036

 

		7.	Please make your subscription payment payable to the order of “Signature Bank, as Escrow
Agent for Protea Biosciences Group, Inc.” Account No. 1503002287

 

For
wiring funds directly to the escrow account, use the following instructions:

 

Signature Bank 

261 Madison Avenue 

New York, NY 10016 

		Acct. Name:	Signature Bank as Escrow Agent for
	 	 	Protea
                                         Biosciences Group, Inc.

ABA Number: 026013576 

SWIFT Code: SIGNUS33 

A/C Number: 1503002287

FBO: Purchaser Name 

Social Security Number 

Address

 

ALL SUBSCRIPTION DOCUMENTS MUST BE COMPLETELY
FILLED IN, AND SIGNED AS DESCRIBED ABOVE.

 

    	23

     

    

 

ANTI-MONEY LAUNDERING REQUIREMENTS

 

	The USA PATRIOT Act	What is money laundering?	How big is the problem and why is it important?
	 	 	 
	The USA PATRIOT Act is designed to detect, deter, and punish terrorists in the United States and abroad.  The Act imposes new anti-money laundering requirements on brokerage firms and financial institutions.  Since April 24, 2002 all brokerage firms have been required to have new, comprehensive anti-money laundering programs. To help you understand these efforts, we want to provide you with some information about money laundering and our steps to implement the USA PATRIOT Act.	Money laundering is the process of disguising illegally obtained money so that the funds appear to come from legitimate sources or activities.  Money laundering occurs in connection with a wide variety of crimes, including illegal arms sales, drug trafficking, robbery, fraud, racketeering, and terrorism.	The use of the U.S. financial system by criminals to facilitate terrorism or other crimes could well taint our financial markets.  According to the U.S. State Department, one recent estimate puts the amount of worldwide money laundering activity at $1 trillion a year.

 

	What are we required to do to eliminate money laundering?
	 	 
	Under new rules required by the USA PATRIOT Act, our anti-money laundering program must designate a special compliance officer, set up employee training, conduct independent audits, and establish policies and procedures to detect and report suspicious transaction and ensure compliance with the new laws.	As part of our required program, we may ask you to provide various identification documents or other information.  Until you provide the information or documents we need, we may not be able to effect any transactions for you.

 

    	24

     

    

 

PROTEA BIOSCIENCES GROUP, INC.

SIGNATURE PAGE TO

SUBSCRIPTION AGREEMENT 

 

AGGREGATE NUMBER OF UNITS BEING PURCHASED
= _________ UNITS 

 

AGGREGATE PURCHASE PRICE OF THE UNITS =
$_________ (the “Purchase Price”, or $10,000, multiplied by the total number of Units being purchased: to be completed
by the Purchaser)

 

Date (NOTE: To be completed by the Purchaser):
__________________, 201__

 

If the Purchaser is an INDIVIDUAL, and if purchased
as JOINT TENANTS, as TENANTS IN COMMON, or as COMMUNITY PROPERTY:

 

	 	 	 	 	 
	 	Print Name(s)	 	Social Security Number(s)	 
	 	 	 	 	 
	 	Print Name(s)	 	Social Security Number(s)	 
	 	 	 	 	 
	 	Signature of Purchaser	 	Signature of Co-Purchaser (if applicable):	 
	 	 	 	 	 
	 	Address:	 	 	 
	 	 	 	 	 
	 	 	 	Date	 
	 	 	 	 	 

 

 

 

If the Purchaser is a PARTNERSHIP,
CORPORATION, LIMITED LIABILITY COMPANY or TRUST:

 

	 	 	 	 	 
	 	 	 	Federal Taxpayer	 
	 	Name of Partnership,	 	Identification Number	 
	 	Corporation, Limited	 	 	 
	 	Liability Company or Trust	 	 	 
	 	 	 	 	 	 
	 	By:	 	 	 	 
	 	 	Name:	 	State of Organization	 
	 	 	Title:	 	 	 
	 	 	 	 	 
	 	Address:	 	 	 
	 	 	 	 	 
	 	 	 	Date	 
	 	 	 	 	 

 

	AGREED AND ACCEPTED:	 	 	 
	 	 	 	 
	PROTEA BIOSCIENCES GROUP, INC.	 	 	 
	 	 	 	 	 	 
	By:	 	 	 	 
	 	Name:	Stephen Turner	 	Date	 
	 	Title:	Chief Executive Officer	 	 	 

 

     

     

    

 

FORM OF INVESTOR QUESTIONNAIRE

 

PROTEA BIOSCIENCES GROUP, INC.

 

For Individual Investors Only

 

(All individual investors must INITIAL
where appropriate. Where there are joint investors both parties must INITIAL):

 

	Initial _______ 	I certify that I have a “net worth” of at least $1 million either individually or through aggregating my individual holdings and those in which I have a joint, community property or other similar shared ownership interest with my spouse.  For purposes of calculating net worth under this paragraph, (i) the primary residence shall not be included as an asset, (ii) to the extent that the indebtedness that is secured by the primary residence is in excess of the fair market value of the primary residence, the excess amount shall be included as a liability, and (iii) if the amount of outstanding indebtedness that is secured by the primary residence exceeds the amount outstanding 60 days prior to the execution of this Subscription Agreement, other than as a result of the acquisition of the primary residence, the amount of such excess shall be included as a liability.
	 	 
	Initial _______	I certify that I have had an annual gross income for the past two years of at least $200,000 (or $300,000 jointly with my spouse) and expect my income (or joint income, as appropriate) to reach the same level in the current year.
	 	 
	For Non-Individual Investors
	 
	(all Non-Individual Investors must INITIAL where appropriate):
	 	 
	Initial _______	The undersigned certifies that it is a partnership, corporation, limited liability company or business trust that is 100% owned by persons who meet either of the criteria for Individual Investors, above.
	 	 
	Initial _______	The undersigned certifies that it is a partnership, corporation, limited liability company or business trust that has total assets of at least $5 million and was not formed for the purpose of investing in Company.
	 	 
	Initial _______	The undersigned certifies that it is an employee benefit plan whose investment decision is made by a plan fiduciary (as defined in ERISA §3(21)) that is a bank, savings and loan association, insurance company or registered investment adviser.
	 	 
	Initial _______	The undersigned certifies that it is an employee benefit plan whose total assets exceed $5,000,000 as of the date of the Subscription Agreement.
	 	 
	Initial _______	The undersigned certifies that it is a self-directed employee benefit plan whose investment decisions are made solely by persons who meet either of the criteria for Individual Investors, above.

 

    	A-1

     

    

 

	Initial _______	The undersigned certifies that it is a U.S. bank, U.S. savings and loan association or other similar U.S. institution acting in its individual or fiduciary capacity.
	 	 
	Initial _______	The undersigned certifies that it is a broker-dealer registered pursuant to §15 of the Securities Exchange Act of 1934.
	 	 
	Initial _______	The undersigned certifies that it is an organization described in §501(c)(3) of the Internal Revenue Code with total assets exceeding $5,000,000 and not formed for the specific purpose of investing in Company.
	 	 
	Initial _______	The undersigned certifies that it is a trust with total assets of at least $5,000,000, not formed for the specific purpose of investing in Company, and whose purchase is directed by a person with such knowledge and experience in financial and business matters that he is capable of evaluating the merits and risks of the prospective investment.
	 	 
	Initial _______	The undersigned certifies that it is a plan established and maintained by a state or its political subdivisions, or any agency or instrumentality thereof, for the benefit of its employees, and which has total assets in excess of $5,000,000.
	 	 
	Initial _______	The undersigned certifies that it is an insurance company as defined in §2(a)(13) of the Securities Act of 1933, as amended, or a registered investment company.

 

    	A-2

     

    

 

PROTEA BIOSCIENCES GROUP, INC.

Investor Questionnaire

(Must be completed by Purchaser)

 

Section A - Individual Purchaser Information

EXACT Purchaser Name(s) in which securities are to be issued: ________________________________________________________________________

 

Individual executing Profile or Trustee: _______________________________________________________________________

 

Social Security Numbers / Federal I.D. Number: ________________________________________________________________________

Date of Birth: _________________ Marital Status: _________________

Joint Party Date of Birth:_________________ 

Investment Experience (Years): ___________

Annual Income: _________________ 

Net Worth: ________________

Home Street Address: ________________________________________________________________________

 

Home City, State & Zip Code: ________________________________________________________________________

 

Home Phone: ________________________ Home Fax: _____________________

 

Home Email: _______________________________

 

Employer: ________________________________________________________________________

 

Employer Street Address: ________________________________________________________________________

 

Employer City, State & Zip Code: ________________________________________________________________________

 

Bus. Phone: __________________________ Bus. Fax: _______________________

 

Bus. Email: ________________________________

 

Type of Business: ________________________________________________________________________

 

LAIDLAW Account Executive / Outside Broker/Dealer: _______________________________________________________

 

Please check if you are a FINRA member or affiliate of a FINRA member
firm: _______

 

    	A-3

     

    

 

Section B – Entity Purchaser Information

 

EXACT Purchaser Name(s) in which securities are to be issued: ________________________________________________________________________

 

Authorized Individual executing Profile or Trustee: _______________________________________________________________________

 

Social Security Numbers / Federal I.D. Number: ________________________________________________________________________

 

Investment Experience (Years): ___________

 

Net Worth: ________________

 

Was the Trust formed for the specific purpose of purchasing the
Securities?

 

 ̈ Yes  ̈
No

 

Principal Purpose (Trust)______________________________________

 

Type of Business: ________________________________________________________

Street Address: ________________________________________________________________________

 

City, State & Zip Code: ________________________________________________________________________

 

Phone: ________________________ Fax: ________________________

 

Email: __________________________

 

Laidlaw Account Executive / Outside Broker/Dealer:

 

_______________________________________________________

 

Please check if you are a FINRA member or affiliate of a FINRA member
firm: _______

 

    	A-4

     

    

 

Section C – Form of Payment –
Check or Wire Transfer

 

		____	Check payable to “SIGNATURE BANK, AS ESCROW AGENT FOR PROTEA BIOSCIENCES GROUP, INC.

 

		____	Wire funds from my outside account according to the “To subscribe for the Series A Preferred Stock and Warrants to Purchase
Shares of Common Stock in the private offering of PROTEA BIOSCIENCES GROUP, INC.”

 

		____	Wire funds from my LAIDLAW Account – See following
page

 

	 	Section D – Purchaser Instructions for Payments of any Dividends
	 	 
	 ̈	Please make any dividend and any other payment checks pursuant to the Securities to “Sterne Agee & Leach Inc. c/f Insert Client Name]” and deliver such checks to Laidlaw so that they may deposit them into my Laidlaw brokerage account
	 	 
	 ̈	Please make out any dividend and any other payment checks pursuant to the Securities in the registered name of the Purchaser set forth in the signature page to the Subscription Agreement for the Securities and mail such checks to me at the address specified in such signature page.

 

Section E – Securities Delivery
Instructions (check one)

 

		____	Please deliver my securities
to Laidlaw for deposit into my brokerage account.

 

		____	Please deliver my securities to the address listed in the
above Investor Questionnaire.

 

		____	Please deliver my securities to the below address:

______________________________________

______________________________________

______________________________________

______________________________________

 

	Purchaser Signature(s) __________________________________________________	Date_______________ 

 

	Joint Purchaser Signature (if applicable): ___________________________________	Date_______________

 

    	A-5

     

    

 

Wire Transfer Authorization

 

		TO:	OPERATIONS MANAGER

			LAIDLAW & CO. (UK) LTD.

 

		RE:	Client Wire Transfer Authorization

			PROTEA BIOSCIENCES GROUP, INC.

 

		DATE:	________________

 

 

 

This memorandum authorizes the transfer of the following
listed funds from my LAIDLAW Brokerage Account as follows:

 

	LAIDLAW Brokerage Account #	  ______________________
	 	 
	Wire Amount	$______________________

 

SIGNATURE BANK

261 Madison Avenue 

New York, NY 10016 

ABA Number: 026013576 

For Credit to Signature Bank, as
Escrow Agent for 

Protea Biosciences Group, Inc.

Account No.: 1503002287 

 

REFERENCE:

 

PURCHASER'S LEGAL NAME

______________________________________________________

 

TAX ID NUMBER

______________________________________________________

 

PURCHASER'S ADDRESS

______________________________________________________

 

FBO:  ________________________________________________

 

	Signature:	________________________________________________
	 	 
	Signature:	________________________________________________
	 	(Joint Signature)

 

    	A-6

     

    

 

Exhibit A

 

Selling Stockholder Notice and Questionnaire

 

Protea
Biosciences Group, Inc.

 

Selling
Stockholder Notice and Questionnaire

 

The undersigned beneficial
owners of shares series A preferred stock, which is convertible into shares of the Company’s common stock, par value $0.0001
per share (the “Common Stock”) and warrants to purchase shares of Common Stock (each, a “Warrant”)
of Protea Biosciences Group, Inc. (the “Company”), understand that the Company has filed or intends to file
with the Securities and Exchange Commission (the “Commission”) a registration statement on Form S-1 (the “Registration
Statement”) under the Securities Act of 1933, as amended (the “Securities Act”) for the registration
of the resale of the shares of Common Stock issuable upon exercise of the series A preferred stock (the “Conversion Shares”)
and the shares of Common Stock issuable upon exercise of the Warrants (the “Warrant Shares”) held by the undersigned
(collectively, the “Registrable Securities”). This Questionnaire is being furnished to you and other stockholders
whose Conversion Shares and Warrant Shares will be included in the Registration Statement. This Questionnaire seeks information
necessary to complete the registration of these shares with the SEC.

 

To sell or otherwise dispose
of any Registrable Securities in the offering, a holder or beneficial owner of Registrable Securities will be required to agree
to be named as a selling stockholder in the related prospectus and execute and return this Selling Stockholder Questionnaire.

 

Please respond to every
question unless otherwise directed. If the answer is “none” or “not applicable,” please so state. Please
include all information sought by the related question. Unless stated otherwise, answers should be given as of the date you complete
this Questionnaire. If there is any response or underlying factual matter about which you are uncertain, please discuss the matter
fully and include any additional explanation or information which you believe is helpful.

 

Certain legal consequences
arise from being named as a selling stockholder in the Registration Statement and the related prospectus. Accordingly, holders
and beneficial owners of Registrable Securities are advised to consult their own securities law counsel regarding the consequences
of being named or not being named as a selling stockholder in the Registration Statement and the related prospectus.

 

NOTICE

 

The undersigned beneficial
owner (the “Selling Stockholder”) of Registrable Securities hereby elects to register for resale the Registrable
Securities owned by it and listed below in Question 5 (unless otherwise specified under such Question 5) in the Registration Statement.

 

    	A-7

     

    

 

The undersigned hereby provides the following
information to the Company and represents and warrants that such information is accurate:

 

QUESTIONNAIRE

 

		1.	Name. Full Legal Name of Selling Stockholder:

 

	 
	 

 

		2.	Address for Notices to Selling Stockholder.

 

 

 

 

 

 

 

	Telephone:	 

	Fax:	 

	Email address:	 

	Contact Person: 	 

 

		3.	Relationship with the Company.

 

Describe the nature of any position,
office or other material relationship the Selling Stockholder has had with the Company during the past three years:

	 	 	 
	 	 	 
	 	 	 
		4.	Organizational Structure. Please indicate or (if applicable) describe how the Selling Stockholder is organized.

 

		(a)	Is the Selling Stockholder a natural person? (If so, please mark the box and skip to Question
5.)

 

Yes    ̈
      No    ̈

 

		(b)	Is the Selling Stockholder a reporting company under the Securities Exchange Act of 1934, as amended
(the “Exchange Act”)? (If so, please mark the box and skip to Question 5.)

 

Yes    ̈
      No    ̈

 

		(c)	Is the Selling Stockholder a majority-owned subsidiary of a reporting company under the Exchange
Act? (If so, please mark the box and skip to Question 5.)

 

Yes    ̈
      No    ̈

 

		(d)	Is the Selling Stockholder a registered investment company under the Investment Company Act of
1940? (If so, please mark the box and skip to Question 5.)

 

Yes    ̈
      No    ̈

 

    	A-8

     

    

 

If the answer to all of the foregoing
questions is “no,” please complete the following:

 

		(e)	Legal Description of Selling Stockholder:

 

			Please describe the type of legal entity that the Selling Stockholder is (e.g., corporation, partnership,
limited liability company, etc.);

 

	 
	 

		(f)	Please indicate whether the Selling Stockholder is controlled by another entity (such
as a parent company, a corporate member, corporate shareholder, etc.) or is controlled by a natural person.

 

Controlled by:           Natural
Person(s)    ̈    Entity    ̈

 

			If you checked “Natural Person(s)”:

 

			Please indicate the name of the natural person(s) who has voting or investment control over
the shares held by the Selling Stockholder and the position of control that person(s) holds in or over the Selling Stockholder,
then move to Question 5.

 

			Name of natural person(s):_____________________________________

 

			Controlling position in Selling Stockholder (e.g., sole member, controlling shareholder, sole stockholder, trustee, etc.):
_____________ __________________________________________________________

 

			If you checked “Entity”:

 

			Please indicate the name and type of entity that controls the Selling Stockholder.

 

			Name of controlling entity: ____________________________________

 

			Type of legal entity (e.g., corporation, partnership, limited liability company, etc.): ______________________________________________

 

			Is this entity controlled by another entity (such as a parent company, a corporate
member, corporate shareholder, etc.) or is it controlled by a natural person?

 

Controlled by:           Natural
Person(s)    ̈    Entity *  ̈

 

If you checked “Natural
Person(s)”:

 

			Name of natural person(s) who controls this entity and has voting or investment control over the shares held by the Selling
Stockholder the Selling Stockholder: ____________________________________________________

 

			Natural person’s position in this entity (e.g., sole member, controlling shareholder, sole stockholder, trustee, etc.):
____________________________________________________

 

    	A-9

     

    

 

*If you answered
“Entity” here, please repeat step (f) for each controlling entity moving up the corporate chain of control until you
reach the level at which there is only a natural person or persons in control (e.g., Acme LLC is controlled by ABC Corp., its member,
which is controlled by X shareholder, its controlling shareholder). List the name of the entities along that chain of control,
the types of entity each is, the natural person(s) in control of the ultimately controlling entity, and his or her control position
over that entity in the lines below:

 

	 
	 
	 
	 
	_____________________________________

 

(Continued on
next page...)

 

    	A-10

     

    

 

		5.	Beneficial Ownership of Registrable Securities:

 

This question covers
beneficial ownership of the Company's securities. Please consult Attachment A to this Questionnaire for information
as to the meaning of “beneficial ownership.”

 

		(a)	Please state the number of shares of the Company’s Common Stock (including any shares issuable
upon exercise of warrants or other convertible securities) that the Selling Stockholder beneficially owns as of the date of this
Questionnaire:

 

	 
	 
	 

		(b)	Please state the number of shares of the Registrable Securities that the Selling Stockholder wishes
to have registered for resale in the Registration Statement.

 

			Common Stock: ______________________

 

Warrants: _________________
(convertible into ______________ shares of Common Stock).

 

		6.	Broker-Dealer Status:

 

		(a)	Is the Selling Stockholder a broker-dealer?

 

Yes  ̈
       No  ̈

 

		(b)	If “yes” to Question 6(a), did the Selling Stockholder receive the Registrable Securities
as compensation for investment banking services to the Company?

 

Yes  ̈
       No  ̈

 

		Note:	If the answer to Question 6(b) is no, Commission’s staff has indicated that you should be
identified as an underwriter in the Registration Statement.

 

		(c)	Is the Selling Stockholder an affiliate of a broker-dealer?

 

Yes  ̈
       No  ̈

 

		(d)	If the Selling Stockholder is an affiliate of a broker-dealer, does the Selling Stockholder certify
that it purchased the Registrable Securities in the ordinary course of business, and at the time of the purchase of the Registrable
Securities to be resold, the Selling Stockholder had no agreements or understandings, directly or indirectly, with any person to
distribute the Registrable Securities?

 

Yes  ̈
       No  ̈

 

    	A-11

     

    

 

		Note:	If the answer to Question 6(d) no, the Commission’s staff has indicated that you should be
identified as an underwriter in the Registration Statement.

 

		7.	Legal Proceedings with the Company. Is the Company a party to any pending legal proceeding
in which the Selling Stockholder is named as an adverse party?

 

Yes  ̈
       No  ̈

 

State any exceptions
here:

 

	 

 

		8.	Reliance on Responses. The undersigned acknowledges and agrees that the Company and its legal counsel shall be entitled
to rely on its responses in this Questionnaire in all matters pertaining to the Registration Statement and the sale of any Registrable
Securities pursuant to the Registration Statement. 

 

[SIGNATURE
PAGE FOLLOWS]

 

    	A-12

     

    

 

The undersigned agrees
to promptly notify the Company of any inaccuracies or changes in the information provided herein that may occur subsequent to the
date hereof at any time while the Registration Statement remains effective.

 

By signing below, the undersigned
consents to the disclosure of the information contained herein in its answers to Questions 1 through 7 and the inclusion of such
information in the Registration Statement and the related prospectus and any amendments or supplements thereto.

 

IN WITNESS WHEREOF
the undersigned, by authority duly given, has caused this Notice and Questionnaire to be executed and delivered either in person
or by its duly authorized agent.

 

	Dated:	 	 	Beneficial Owner:	 

 

	 	 	 	By:	 
	 	 	 	 	Name:	 
	 	 	 	 	Title:	 

 

PLEASE FAX OR PDF A COPY OF THE COMPLETED
AND EXECUTED NOTICE AND QUESTIONNAIRE, AND RETURN THE ORIGINAL TO:

 

    	A-13

     

    

 

ATTACHMENT A

 

DEFINITION OF “BENEFICIAL
OWNERSHIP”

 

		1.	A “Beneficial Owner” of a security includes any person who, directly or indirectly,
through any contract, arrangement, understanding, relationship or otherwise has or shares:

 

(a)          Voting power which includes
the power to vote, or to direct the voting of, such security; and/or

 

(b)          Investment power which includes
the power to dispose, or direct the disposition of, such security.

 

Please note that either voting power
or investment power, or both, is sufficient for you to be considered the beneficial owner of shares.

 

		2.	Any person who, directly or indirectly, creates or uses a trust, proxy, power of attorney, pooling
arrangement or any other contract, arrangement or device with the purpose or effect of divesting such person of beneficial ownership
of a security or preventing the vesting of such beneficial ownership as part of a plan or scheme to evade the reporting requirements
of the federal securities acts shall be deemed to be the beneficial owner of such security.

 

		3.	Notwithstanding the provisions of paragraph (1), a person is deemed to be the “beneficial
owner” of a security if that person has the right to acquire beneficial ownership of such security within 60 days, including
but not limited to any right to acquire: (a) through the exercise of any option, warrant or right; (b) through the conversion of
a security; (c) pursuant to the power to revoke a trust, discretionary account or similar arrangement; or (d) pursuant to the automatic
termination of a trust, discretionary account or similar arrangement; provided, however, any person who acquires a security or
power specified in (a), (b) or (c) above, with the purpose or effect of changing or influencing the control of the issuer, or in
connection with or as a participant in any transaction having such purpose or effect, immediately upon such acquisition shall be
deemed to be the beneficial owner of the securities which may be acquired through the exercise or conversion of such security or
power. 

 

    	A-14

     

    

 

FORWARD-LOOKING STATEMENTS

 

We have included in this Agreement, including
the Schedule, certain forward-looking statements. Such statements can be identified by the use of forward-looking terminology such
as “believe,” “expect,” “may,” “should,” “seek,” “on-track,”
“plan,” “project,” “forecast,” “intend” or “anticipate,” or the negative
thereof or comparable terminology, or by discussions of vision, strategy or outlook, including statements related to revenues and
profitability, pricing and competition, the continued viability of our technology, our growth and expansion plans, including retaining
new employees, compliance with governmental regulations, our intellectual property protection strategies, payment of dividends,
the volatility of our common stock and the market for our common stock, dilution, trading restrictions, use of proceeds and the
need for additional debt or equity funding. You are cautioned that our business and operations are subject to a variety of risks
and uncertainties, many of which are beyond our control and, consequently, our actual results may differ materially from those
projected by any forward-looking statements. See the section titled “Risk Factors” on Schedule 3A.9 and those described
under the heading “Risk Factors” contained in the Company’s Annual Report on Form 10-K filed with
the SEC on March 16, 2016, for information regarding certain important factors that could cause our actual results to differ materially
from those projected in our forward-looking statements. Our forward-looking statements contained herein speak only as of the date
of this Agreement. We make no commitment to revise or update any forward-looking statements in order to reflect events or circumstances
after the date any such statements are made. 

 

    	A-15Exhibit 10.2 

 

PROTEA BIOSCIENCES GROUP,
INC.

 

REGISTRATION RIGHTS AGREEMENT

 

THIS REGISTRATION
RIGHTS AGREEMENT (the “Agreement”), dated as of the date set forth on the signature page hereto,
is made by and between Protea Biosciences Group, Inc., a Delaware corporation (the “Company”)
and the undersigned investor (the “Investor”).

RECITALS

 

WHEREAS, in
connection with that certain Subscription Agreement of even date herewith by and between the Company and the Investor (the “Subscription
Agreement”) the Investor purchased from the Company, certain units (the “Units”), each
Unit consisting of (a) 10,000 shares of our Series A convertible preferred stock, par value $0.0001 per share and $1.00 stated
or liquidation value per share (the “Series A Preferred Stock”), (b) 18 month warrants to purchase up
to 133,333 shares of common stock, par value $0.0001 per share (the “Common Stock”), at an exercise price
of $0.09 per share (the “Class A Warrants”), and (c) five year warrants purchase up to 133,333 shares
of Common Stock at an exercise price of $0.1125 per share (the “Class B Warrants” and together with the
Class A Warrants, collectively, the “Warrants”). .

 

WHEREAS, to
induce the Investor to purchase the Units, the Company has agreed to grant the Investor certain rights with respect to registration
of Registrable Securities under the Securities Act pursuant to the terms of this Agreement.

 

AGREEMENT

 

NOW,
THEREFORE, the Company and the Investor hereby covenant and agree as follows:

 

1.          Recitals.
The recitals set forth above are true and correct and are incorporated herein by reference.

 

2.          Certain
Definitions. As used in this Agreement, the following terms shall have the following respective meanings:

 

“Agreement”
shall have the meaning set forth in the Preamble hereof.

 

“Automatic Registration
Statement” shall have the meaning set forth in Section 3(a) of this Agreement.

 

“Closing”
shall mean the closing of the sale of the Units in which the Investor purchased the Units.

 

“Closing Date”
means the date on which the Closing occurred.

 

“Class A Warrants”
shall have the meaning set forth in the Preamble hereof.

 

“Class B Warrants”
shall have the meaning set forth in the Preamble hereof.

 

    	 	1	 

     

    

 

“Commission”
shall mean the Securities and Exchange Commission or any other federal agency at the time administering the Securities Act.

 

“Common Stock” shall have
the meaning set forth in the Preamble hereof.

 

“Company”
shall have the meaning set forth in the Preamble hereof.

 

“Conversion
Shares” shall mean the shares of Common Stock to be issued upon conversion of the Series A Preferred Stock.

 

“Effectiveness
Date” shall mean that date which is thirty (30) days following the date on which the Company is notified that the
Commission will not review the Automatic Registration Statement (and in such case of no Commission review, not later than sixty
(60) days following the Filing Deadline) or, in the event of a Commission review, within one hundred eighty (180) days following
the Filing Date.

 

“Effectiveness
Period” shall have the meaning set forth in Section 3(a) of this Agreement.

 

“Event”
shall have the meaning set forth in Section 3(c) of this Agreement.

 

“Event Date”
shall have the meaning set forth in Section 3(c) of this Agreement.

 

“Exchange Act”
shall mean the Securities Exchange Act of 1934, as amended.

 

“Excluded
Registrable Securities” shall have the meaning set forth in Section 4(a) of this Agreement.

 

“Existing
Registrable Securities” shall mean up to an aggregate of 365,979,481 shares of Common Stock outstanding, or shares
of Common Stock underlying outstanding warrants of the Company, as of the initial Closing which are subject to piggy-back registration
rights

 

“Filing
Date” shall mean that date which is forty five (45) days following the Final Closing Date and, with
respect to any additional Registration Statements which may be required herein, the earliest practical date on which the Company
is permitted by SEC Guidance to file such additional Registration Statement related to the Registrable Securities.

 

“Final Closing
Date” means the final closing date of the Offering after which the Company ceases to offer the Units for sale.

 

“Investor”
shall have the meaning set forth in the Preamble hereof.

 

“Investor Representative”
shall mean legal counsel appointed to represent the Investors.

 

“Offering”
shall have the meaning set forth in the Subscription Agreement.

 

“Order
of Cutback” shall have the meaning set forth in Section 3(a) of this Agreement.

 

“Piggyback
Registration” shall have the meaning set forth in Section 4(a) of this Agreement.

 

    	 	2	 

     

    

 

“Prospectus”
means the prospectus included in a Registration Statement (including, without limitation, a prospectus that includes any information
previously omitted from a prospectus filed as part of an effective registration statement in reliance upon Rule 430A promulgated
by the Commission pursuant to the Securities Act), as amended or supplemented by any prospectus supplement, with respect to the
terms of the offering of any portion of the Registrable Securities covered by a Registration Statement, and all other amendments
and supplements to the Prospectus, including post-effective amendments, and all material incorporated by reference or deemed to
be incorporated by reference in such Prospectus.

“Purchase
Agreement” shall have the meaning set forth in the Preamble hereof.

 

“Purchase
Price” shall have the meaning set forth in the Purchase Agreement.

 

“Register,”
“registered” and “registration” each shall refer to a registration of the Registrable
Securities effected by preparing and filing a Registration Statement or statements or similar documents in compliance with the
Securities Act and the declaration or ordering of effectiveness of such Registration Statement or document by the Commission.

 

“Registrable
Securities” shall mean (a) all Conversion Shares then issuable upon conversion of the Series A Preferred Stock included
in the Units delivered to Investor in connection with the Offering, (b) all Warrant Shares then issuable upon exercise of the Warrants
included in the Units delivered to Investor in connection with the Offering (assuming on such date the Warrants are exercised in
full without regard to any exercise limitations therein), (c) all shares of Common Stock issuable upon exercise of the warrants
to be issued to Laidlaw and its agents in connection with the Offering (assuming on such date such warrants are exercised in full
without regard to any exercise limitations therein) and (d) any securities issued or then
issuable upon any stock split, dividend or other distribution, recapitalization or similar event with respect to the foregoing;
provided, however, that any such Registrable Securities shall cease to be Registrable Securities (i) when subject
to an effective Registration Statement under the Securities Act as provided for hereunder, (ii) upon any sale pursuant to a Registration
Statement or Rule 144 under the Securities Act or (iii) at such time such securities become eligible for resale without volume
or manner-of-sale restrictions and without current public information pursuant to Rule 144 as set forth in a written opinion letter
to such effect, addressed, delivered and acceptable to the Transfer Agent and the affected Investors.

 

“Registration
Statement” means any registration statement required to be filed hereunder pursuant to Sections 3 or 4 and any additional
registration statements contemplated herein, including (in each case) the Prospectus, amendments and supplements to any such registration
statement or Prospectus, including pre- and post-effective amendments, all exhibits thereto, and all material incorporated by reference
or deemed to be incorporated by reference in any such registration statement.

 

“Rule
415” means Rule 415 promulgated by the Commission pursuant to the Securities Act, as such Rule may be amended or
interpreted from time to time, or any similar rule or regulation hereafter adopted by the Commission having substantially the same
purpose and effect as such Rule.

 

“Rule
424” means Rule 424 promulgated by the Commission pursuant to the Securities Act, as such Rule may be amended or
interpreted from time to time, or any similar rule or regulation hereafter adopted by the Commission having substantially the same
purpose and effect as such Rule.

 

    	 	3	 

     

    

 

“SEC
Guidance” means (i) any publicly-available written or oral guidance, comments, requirements or requests of the Commission
staff and (ii) the Securities Act.

 

“Securities Act” shall
mean the Securities Act of 1933, as amended.

 

“Series A Preferred Stock”
shall have the meaning set forth in the Preamble hereof.

 

“Shares” shall have the
meaning set forth in the Preamble hereof.

 

“Subscription Agreement”
shall have the meaning set forth in the first Recital hereof.

 

“Warrants” shall have
the meaning set forth in the Preamble hereof.

 

“Warrant
Shares” shall mean the shares of Common Stock to be issued upon exercise of the Warrants.

 

“Units”
shall have the meaning set forth in the Preamble hereof.

 

Capitalized
terms used but not defined herein shall have the meanings set forth in the Subscription Agreement.

 

3.          Automatic
Registration.

 

(a)          On
or prior to the Filing Date, the Company shall prepare and file with the Commission a registration statement (the “Automatic
Registration Statement”) covering the resale of all of the Registrable Securities and (2) the Existing Registrable
Securities for an offering to be made on a continuous basis pursuant to Rule 415.

 

Except as
contemplated in the immediately preceding paragraph, the Company agrees that it will not file any other registration statement
that does not include all of the Registrable Securities prior to the Filing Deadline. The Automatic Registration Statement required
hereunder shall be on Form S-1 or Form S-3, as applicable, and shall contain substantially the “Plan of Distribution”
attached hereto as Annex A. Subject to the terms of this Agreement, the Company shall use its reasonable best efforts to
cause the Automatic Registration Statement to be declared effective under the Securities Act as promptly as possible after the
filing thereof, but in any event not later than the Effectiveness Date, and shall use its best efforts to keep the Automatic Registration
Statement continuously effective under the Securities Act until the earlier of the date when all Registrable Securities covered
by the Registration Statement have been sold thereunder or pursuant to Rule 144 or (ii) may be sold without volume or manner-of-sale
restrictions pursuant to Rule 144 and without the requirement for the Company to be in compliance with the current public information
requirement under Rule 144, as determined by counsel to the Company pursuant to a written opinion letter to such effect, addressed
and acceptable to the Company’s transfer agent and the Investor (the “Effectiveness Period”).
The maximum amount of Registrable Securities or Existing Registrable Securities that may be included in the Automatic Registration
Statement at any one time shall be limited by Rule 415 or as may otherwise be required by the Commission. In the event that there
is a limitation by the Commission on the number of Registrable Securities or Existing Registrable Securities that may be included
for registration on the Automatic Registration Statements at one time, the removal of the securities shall be applied, first to,
the Existing Registrable Securities on a pro rata basis then, to the Conversion Shares on a pro rata basis then, to the Warrant
Shares underlying the Class A Warrants on a pro rata basis and finally to the Warrant Shares underlying the Class B Warrants on
a pro rata basis (the “Order of Cutback”). In the event, any Registrable Securities shall be removed
from the Registration Statement, the Company shall promptly advise any Investor holding such Registrable Securities and use its
best efforts to file an additional Automatic Registration Statement covering such ineligible Registrable Securities, on a pro-rata
basis, within 30 days of the date such securities become eligible for registration, which date shall be determined by the Commission,
and shall use its best efforts to cause such Automatic Registration Statement to be declared effective by the Commission as soon
as reasonably practicable. In addition, if following the initial filing of the Automatic Registration Statement, the Company reasonably
determines for any reason, after consultation with the Placement Agent, that the offering which is subject to the Automatic Registration
Statement needs to be cut back then the Company may cut back the number of Registrable Securities or Existing Registrable Securities
subject to the Automatic Registration Statement in accordance with the Order of Cutback.

 

    	 	4	 

     

    

 

(b)          At
any time after the Automatic Registration Statement has become effective, the Company may, upon giving prompt written notice of
such action to the Investor, suspend the use of any such Automatic Registration Statement if, in the good faith judgment of the
Company, the use of the Automatic Registration Statement covering the Registrable Securities would be detrimental to the Company
or its stockholders at such time and the Company concludes, as a result, that it is in the best interests of the Company or its
stockholders to suspend the use of such Automatic Registration Statement at such time. The Company shall have the right to suspend
such Automatic Registration Statement for a period of not more than thirty (30) consecutive days from the date the Company notifies
the Investor of such suspension, with such suspension not to exceed an aggregate of sixty (60) days (whether or not consecutive)
during any 12-month period. In the case of the suspension of any effective Automatic Registration Statement, the Investor, immediately
upon receipt of notice thereof from the Company, will discontinue any sales of Registrable Securities pursuant to such Registration
Statement until advised in writing by the Company that the use of such Automatic Registration Statement may be resumed.

 

(c)          If: (i)
the Automatic Registration Statement is not filed on or prior to its Filing Date (if the Company files the Automatic Registration
Statement without affording the Investor Representative the opportunity to review and comment on the same as required by Section
5(a) herein, the Company shall be deemed to have not satisfied this clause (i)), (ii) a Registration Statement registering for
resale all of the Registrable Securities is not declared effective by the Commission by the Effectiveness Date (unless the reason
for such non-registration of all or any portion of the Registrable Securities is as a result of SEC Guidance under Rule 415 or
similar rule which limits the number of Registrable Securities which may be included in a registration statement with respect
to the Investors), or (iii) after the effective date of a Registration Statement, such Registration Statement ceases for any reason
to remain continuously effective as to all Registrable Securities included in such Registration Statement, or the Investors are
otherwise not permitted to utilize the prospectus therein to resell such Registrable Securities, for more than ten (10) consecutive
calendar days or more than an aggregate of fifteen (15) calendar days during any 12-month period (any such failure or breach being
referred to as an “Event”, and for purposes of clause (i), the date on which such Event occurs, and
for purpose of clause (ii) the date on which such ten (10) or fifteen (15) calendar day period, as applicable, is exceeded being
referred to as an “Event Date”), then, in addition to any other rights the Investors may have hereunder
or under applicable law, on each such Event Date and on each monthly anniversary of each such Event Date (if the applicable Event
shall not have been cured by such date) until the applicable Event is cured, the Company shall pay to each Investor an amount
in cash, as partial liquidated damages and not as a penalty, equal to 1.0% of the aggregate purchase price paid by such Investor
pursuant to the Subscription Agreement and Purchase Agreement. The parties agree that the maximum aggregate liquidated damages
payable to an Investor under this Agreement shall be 6% of the aggregate Purchase Price paid by such Investor pursuant to the
Purchase Agreement. If the Company fails to pay any partial liquidated damages pursuant to this Section in full within seven days
after the date payable, the Company will pay interest thereon at a rate of 18% per annum (or such lesser maximum amount that is
permitted to be paid by applicable law) to the Investor, accruing daily from the date such partial liquidated damages are due
until such amounts, plus all such interest thereon, are paid in full. The partial liquidated damages pursuant to the terms hereof
shall apply on a daily pro rata basis for any portion of a month prior to the cure of an Event. Notwithstanding the foregoing,
no payments shall be owed with respect to any period during which all of the holder’s Registrable Shares may be sold by
such holder under Rule 144 without volume or manner-of-sale restrictions pursuant to Rule 144 and without the requirement for
the Company to be in compliance with the current public information requirement under Rule 144.

 

    	 	5	 

     

    

 

4.          Piggyback
Registrations.

 

(a)          With
respect to any Registrable Securities not otherwise included in the Automatic Registration Statement or any other Registration
Statement as a result of any limitation imposed by the Commission under Rule 415 (the “Excluded Registrable Securities”),
whenever the Company proposes to register (including, for this purpose, a registration effected by the Company for other shareholders)
any of its securities under the Securities Act (other than pursuant to (i) an Automatic Registration pursuant to Section 3 hereof
or (ii) registration pursuant to a registration statement on Form S-4 or S-8 or any successor forms thereto), and the registration
form to be used may be used for the registration of Registrable Securities (a “Piggyback Registration”),
the Company will give written notice to the holder of Excluded Registrable Securities of its intention to effect such a registration
and will, subject to the provisions of Subsection 4(b) hereof, include in such registration all Excluded Registrable Securities
with respect to which the Company has received a written request for inclusion therein within twenty (20) days after the receipt
of the Company’s notice.

 

(b)          If
a Piggyback Registration is an underwritten secondary registration on behalf of holders of the Company’s securities, and
the managing underwriters advise the Company in writing that in their opinion the number of securities requested to be included
in such registration exceeds the number which can be sold in such offering without adversely affecting the marketability of the
offering, the Company will include in such registration a pro rata share of Excluded Registrable Securities requested to be included
in such Registration Statement as calculated by dividing the number of Excluded Registrable Securities requested to be included
in such Registration Statement by the number of the Company’s securities requested to be included in such Registration Statement
by all selling security holders. In such event, the holder of Excluded Registrable Securities shall continue to have registration
rights under this Agreement with respect to any Excluded Registrable Securities not so included in such Registration Statement.

 

(c)          Notwithstanding
the foregoing, if, at any time after giving a notice of Piggyback Registration and prior to the effective date of the Registration
Statement filed in connection with such registration, the Company shall determine for any reason not to register or to delay registration
of such securities, the Company may, at its election, give written notice of such determination to each record holder of Excluded
Registrable Securities and, following such notice, (i) in the case of a determination not to register, shall be relieved of its
obligation to register any Excluded Registrable Securities in connection with such registration, and (ii) in the case of determination
to delay registering, shall be permitted to delay registering any Excluded Registrable Securities for the same period as the delay
in registering such other securities.

 

5.          Lock-Up
of Registrable Securities.  Notwithstanding anything to the
contrary, express or implied, contained in this Agreement, in the event and to the extent that the Company and the managing
underwriter or placement agent in connection with any proposed public offering of the Company’s securities shall, in
the exercise of their joint good faith judgment, determine that immediate resales by holders of Registrable Securities could
have a material adverse effect on the Company’s ability to complete the such offering, the Company and such managing
underwriter or placement agent may restrict resales of such Registrable Securities (a “Lock-Up”)
for a period of up to ninety (90) days following the effective date of such offering; provided, that, the
foregoing right to effect a Lock-Up is subject to consummation of the sale or registration for resale of not less than
$15,000,000 of the securities offered for the account of the Company. In connection with the foregoing, appropriate stop
transfer instructions with respect to the Registrable Securities may be given to the transfer agent of the Company.

 

    	 	6	 

     

    

 

6.          Registration
Procedures. If and whenever the Company is required to affect the registration of any Registrable Securities under the terms
herein, the Company will:

 

(a)          
not less than five (5) business days prior to the filing of each Registration Statement and not less than one (1) business day
prior to the filing of any related Prospectus or any amendment or supplement thereto (including any document that would be incorporated
or deemed to be incorporated therein by reference), (i) furnish to each seller of Registrable Securities, copies of all such documents
proposed to be filed, which documents (other than those incorporated or deemed to be incorporated by reference) will be subject
to the review of such sellers, and (ii) cause its officers and directors, counsel and independent registered public accountants
to respond to such inquiries as shall be necessary, in the reasonable opinion of respective counsel to each seller of Registrable
Securities, to conduct a reasonable investigation within the meaning of the Securities Act. Notwithstanding the above, the Company
shall not be obligated to provide each seller of Registrable Securities advance copies of any universal shelf registration statement
registering securities in addition to those required hereunder, or any Prospectus prepared thereto;  

 

(b)          prepare
and file with the Commission the Registration Statement with respect to such securities and use its best efforts to cause such
Registration Statement to become effective in an expeditious manner;

 

(c)          (i)
prepare and file with the Commission such amendments, including post-effective amendments, to a Registration Statement and the
Prospectus used in connection therewith as may be necessary to keep a Registration Statement continuously effective as to the applicable
Registrable Securities for the Effectiveness Period and prepare and file with the Commission such additional Registration Statements
in order to register for resale under the Securities Act all of the Registrable Securities, (ii) cause the related Prospectus to
be amended or supplemented by any required Prospectus supplement (subject to the terms of this Agreement), and, as so supplemented
or amended, to be filed pursuant to Rule 424, (iii) respond as promptly as reasonably possible to any comments received from the
Commission with respect to a Registration Statement or any amendment thereto and provide as promptly as reasonably possible to
each seller of Registrable Securities true and complete copies of all correspondence from and to the Commission relating to a Registration
Statement (provided that, the Company shall excise any information contained therein which would constitute material non-public
information regarding the Company), and (iv) comply in all material respects with the applicable provisions of the Securities Act
and the Exchange Act, with respect to the disposition of all Registrable Securities covered by a Registration Statement during
the applicable period in accordance (subject to the terms of this Agreement) with the intended methods of disposition by each seller
of Registrable Securities thereof set forth in such Registration Statement as so amended or in such Prospectus as so supplemented;

 

(d)          furnish
to each seller of Registrable Securities and to each underwriter such number of copies of the Registration Statement and the Prospectus
included therein (including each preliminary prospectus) as such persons reasonably may request in order to facilitate the intended
disposition of the Registrable Securities covered by such Registration Statement;

 

    	 	7	 

     

    

 

(e)          
if during the Effectiveness Period, the number of Registrable Securities at any time exceeds 100% of the
number of shares of Common Stock then registered in a Registration Statement, then the Company shall file an additional Registration
Statement covering such ineligible Registrable Securities, on a pro-rata basis, within 60 days of the date such securities become
eligible for registration, which date shall be determined by the Commission, and shall use its best efforts to cause such Registration
Statement to be declared effective by the Commission as soon as reasonably practicable;

 

(f)          use
its commercially reasonable efforts (i) to register or qualify the Registrable Securities covered by such Registration Statement
under the state securities or “blue sky” laws of such jurisdictions as the sellers of Registrable Securities or, in
the case of an underwritten public offering, the managing underwriter, reasonably shall request, (ii) to prepare and file in those
jurisdictions such amendments (including post-effective amendments) and supplements, and take such other actions, as may be necessary
to maintain such registration and qualification in effect at all times for the period of distribution contemplated thereby and
(iii) to take such further action as may be necessary or advisable to enable the disposition of the Registrable Securities in such
jurisdictions, provided, that the Company shall not for any such purpose be required to qualify generally to transact business
as a foreign corporation in any jurisdiction where it is not so qualified or to consent to general service of process in any such
jurisdiction;

 

(g)          use
its commercially reasonable efforts to list the Registrable Securities covered by such Registration Statement with any securities
exchange on which the common stock of the Company is then listed;

 

(h)          immediately
notify each seller of Registrable Securities and each underwriter under such Registration Statement, at any time when a Prospectus
relating thereto is required to be delivered under the Securities Act, of the happening of any event of which the Company has knowledge
as a result of which the Prospectus contained in such Registration Statement, as then in effect, includes any untrue statement
of a material fact or omits to state a material fact required to be stated therein or necessary to make the statements therein
not misleading in light of the circumstances then existing and promptly amend or supplement such Registration Statement to correct
any such untrue statement or omission;

 

(i)          if
the offering is an underwritten offering, enter into a written agreement with the managing underwriter selected in the manner herein
provided in such form and containing such provisions as are usual and customary in the securities business for such an arrangement
between such underwriter and companies of the Company’s size and investment stature, including, without limitation, customary
indemnification and contribution provisions;

 

(j)          if
the offering is an underwritten offering, at the request of any seller of Registrable Securities, furnish to such seller on the
date that Registrable Securities are delivered to the underwriters for sale pursuant to such registration: (i) a copy of an opinion,
dated such date, of counsel representing the Company for the purposes of such registration, addressed to the underwriters, stating
that such Registration Statement has become effective under the Securities Act and that (A) to the knowledge of such counsel, no
stop order suspending the effectiveness thereof has been issued and no proceedings for that purpose have been instituted or are
pending or contemplated under the Securities Act, (B) the Registration Statement, the related Prospectus and each amendment or
supplement thereof comply as to form in all material respects with the requirements of the Securities Act (except that such counsel
need not express any opinion as to financial statements or other financial or statistical information contained therein) and (C)
to such other effects as reasonably may be requested by counsel for the underwriters; and (ii) a copy of a letter dated such date
from the independent public accountants retained by the Company, addressed to the underwriters, stating that they are independent
registered public accountants within the meaning of the Securities Act and that, in the opinion of such accountants, the financial
statements of the Company included in the Registration Statement or the Prospectus, or any amendment or supplement thereof, comply
as to form in all material respects with the applicable accounting requirements of the Securities Act, and such letter shall additionally
cover such other financial matters (including information as to the period ending no more than five business days prior to the
date of such letter) with respect to such registration as such underwriters reasonably may request;

 

    	 	8	 

     

    

 

(k)          promptly
notify each seller of Registrable Securities of the issuance by the Commission of any stop order suspending the effectiveness of
the Registration Statement or the initiation of any proceedings for that purpose and make every reasonable effort to prevent the
issuance of any stop order and, if any stop order is issued, to obtain the lifting thereof at the earliest possible time;

 

(l)          take
all actions reasonably necessary to facilitate the timely preparation and delivery of certificates (not bearing any legend restricting
the sale or transfer of such securities) representing the Registrable Securities to be sold pursuant to the Registration Statement
and to enable such certificates to be in such denominations and registered in such names as each seller of Registrable Securities
or any underwriters may reasonably request; and

 

(m)          take
all other reasonable actions necessary to expedite and facilitate the registration of the Registrable Securities pursuant to the
Registration Statement.

 

7.          Obligations
of Investor. The Investor shall furnish to the Company such information regarding such Investor, the number of Registrable
Securities owned and proposed to be sold by it, the intended method of disposition of such securities and any other information
as shall be required to effect the registration of the Registrable Securities, and cooperate with the Company in preparing the
Registration Statement and in complying with the requirements of the Securities Act.

 

8.          Expenses.

 

(a)          All
expenses incurred by the Company in complying with Sections 3, 4 and 5 including, without limitation, all registration and
filing fees (including the fees of the Commission and any other regulatory body with which the Company is required to file), printing
expenses, fees and disbursements of counsel and independent public accountants for the Company, fees and expenses (including counsel
fees of the Company and the Placement Agent, as representative of the Purchasers) incurred in connection with complying with state
securities or “blue sky” laws, and fees of transfer agents and registrars are called “Registration Expenses.”
All underwriting discounts and selling commissions applicable to the sale of Registrable Securities are called “Selling Expenses.”

 

(b)          The
Company will pay all Registration Expenses in connection with any Registration Statement filed hereunder, and the Selling Expenses
in connection with each such Registration Statement shall be borne by the participating sellers in proportion to the number of
Registrable Securities sold by each or as they may otherwise agree.

 

(c)          Notwithstanding
anything herein to the contrary, at the request of any Investor, the Company shall employ its counsel at the Company’s expense
to prepare any and all legal opinions necessary for the prompt removal of restrictive legends from certificates representing Registrable
Securities as, when and to the extent such legends may be removed in compliance with the Securities Act and/or Rule 144.

 

    	 	9	 

     

    

 

9.          Indemnification
and Contribution.

 

(a)          In
the event of a registration of any of the Registrable Securities under the Securities Act pursuant to the terms of this Agreement,
the Company will indemnify and hold harmless and pay and reimburse, each seller of such Registrable Securities thereunder, each
underwriter of such Registrable Securities thereunder and each other person, if any, who controls such seller or underwriter within
the meaning of the Securities Act, against any losses, claims, damages or liabilities, joint or several, to which such seller,
underwriter or controlling person may become subject under the Securities Act or otherwise, insofar as such losses, claims, damages
or liabilities (or actions in respect thereof) arise out of or are based upon any untrue statement or alleged untrue statement
of any material fact contained in any Registration Statement under which such Registrable Securities were registered under the
Securities Act pursuant hereto or any preliminary prospectus or final prospectus contained therein, or any amendment or supplement
thereof, or arise out of or are based upon the omission or alleged omission to state therein a material fact required to be stated
therein or necessary to make the statements therein not misleading, or any violation or alleged violation of the Securities Act
or any state securities or “blue sky” laws and will reimburse each such seller, each such underwriter and each such
controlling person for any legal or other expenses reasonably incurred by them in connection with investigating or defending any
such loss, claim, damage, liability or action; provided, that the Company will not be liable in any such case if and to the extent
that any such loss, claim, damage or liability arises out of or is based upon the Company’s reliance on an untrue statement
or alleged untrue statement or omission or alleged omission so made in conformity with information furnished by any such seller,
any such underwriter or any such controlling person in writing specifically for use in such Registration Statement or prospectus.

 

(b)          In
the event of a registration of any of the Registrable Securities under the Securities Act pursuant hereto, each seller of such
Registrable Securities thereunder, severally and not jointly, will indemnify and hold harmless the Company, each person, if any,
who controls the Company within the meaning of the Securities Act, each officer of the Company who signs the Registration Statement,
each director of the Company, each underwriter and each person who controls any underwriter within the meaning of the Securities
Act, against all losses, claims, damages or liabilities, joint or several, to which the Company or such officer, director, underwriter
or controlling person may become subject under the Securities Act or otherwise, insofar as such losses, claims, damages or liabilities
(or actions in respect thereof) arise out of or are based upon reliance on any untrue statement or alleged untrue statement of
any material fact contained in the registration statement under which such Registrable Securities were registered under the Securities
Act pursuant hereto or any preliminary prospectus or final prospectus contained therein, or any amendment or supplement thereof,
or arise out of or are based upon the omission or alleged omission to state therein a material fact required to be stated therein
or necessary to make the statements therein not misleading, and will reimburse the Company and each such officer, director, underwriter
and controlling person for any legal or other expenses reasonably incurred by them in connection with investigating or defending
any such loss, claim, damage, liability or action; provided that such seller will be liable hereunder in any such case if and only
to the extent that any such loss, claim, damage or liability arises out of or is based upon an untrue statement or alleged untrue
statement or omission or alleged omission made in reliance upon and in conformity with information pertaining to such seller, as
such, furnished in writing to the Company by such seller specifically for use in such Registration Statement or prospectus; and
provided, further, that the liability of each seller hereunder shall be limited to the proceeds received by such seller from the
sale of Registrable Securities covered by such Registration Statement. Notwithstanding the foregoing, the indemnity provided in
this Section 8(b) shall not apply to amounts paid in settlement of any such loss, claim, damage, liability or expense if
such settlement is effected without the consent of such indemnified party and provided further, that the Company shall not be liable
in any such case to the extent that any such loss, claim, damage or liability (or action in respect thereof) arises out of or is
based upon an untrue statement or alleged untrue statement or omission or alleged omission in such Registration Statement, which
untrue statement or alleged untrue statement or omission or alleged omission is completely corrected in an amendment or supplement
to the Registration Statement and the undersigned indemnitees thereafter fail to deliver or cause to be delivered such Registration
Statement as so amended or supplemented prior to or concurrently with the sale of the Registrable Securities to the person asserting
such loss, claim, damage or liability (or actions in respect thereof) or expense after the Company has furnished the undersigned
with the same.

 

    	 	10	 

     

    

 

(c)          Promptly
after receipt by an indemnified party hereunder of notice of the commencement of any action, such indemnified party shall, if a
claim in respect thereof is to be made against the indemnifying party hereunder, notify the indemnifying party in writing thereof,
but the omission so to notify the indemnifying party shall not relieve it from any liability which it may have to such indemnified
party other than under this Section 8 and shall only relieve it from any liability which it may have to such indemnified
party under this Section 8 if and to the extent the indemnifying party is materially prejudiced by such omission. In case
any such action shall be brought against any indemnified party and it shall notify the indemnifying party of the commencement thereof,
the indemnifying party shall be entitled to participate in and, to the extent it shall wish, to assume and undertake the defense
thereof with counsel reasonably satisfactory to such indemnified party, and, after notice from the indemnifying party to such indemnified
party of its election so to assume and undertake the defense thereof, the indemnifying party shall not be liable to such indemnified
party under this Section 8 for any legal expenses subsequently incurred by such indemnified party in connection with the
defense thereof other than reasonable costs of investigation and of liaison with counsel so selected; provided that if the defendants
in any such action include both the indemnified party and the indemnifying party and the indemnified party shall have reasonably
concluded based upon written advice of its counsel that there may be reasonable defenses available to it that are different from
or additional to those available to the indemnifying party or if the interests of the indemnified party reasonably may be deemed
to conflict with the interests of the indemnifying party, the indemnified party shall have the right to select a separate counsel
and to assume such legal defenses and otherwise to participate in the defense of such action, with the expenses and fees of such
separate counsel and other expenses related to such participation to be reimbursed by the indemnifying party as incurred.

 

(d)          In
order to provide for just and equitable contribution to joint liability under the Securities Act in any case in which either (i)
any holder of Registrable Securities exercising rights under this Agreement, or any controlling person of any such holder, makes
a claim for indemnification pursuant to this Section 8 but it is judicially determined (by the entry of a final judgment
or decree by a court of competent jurisdiction and the expiration of time to appeal or the denial of the last right of appeal)
that such indemnification may not be enforced in such case notwithstanding the fact that this Section 8 provides for indemnification
in such case, or (ii) contribution under the Securities Act may be required on the part of any such selling holder or any such
controlling person in circumstances for which indemnification is provided under this Section 8; then, and in each such case,
the Company and such holder will contribute to the aggregate losses, claims, damages or liabilities to which they may be subject
(after contribution from others) in such proportion so that such holder is responsible for the portion represented by the percentage
that the public offering price of its Registrable Securities offered by the Registration statement bears to the public offering
price of all securities offered by such Registration statement, and the Company is responsible for the remaining portion; provided,
that, in any such case, (A) no such holder will be required to contribute any amount in excess of the public offering price of
all such Registrable Securities offered by it pursuant to such Registration statement and (B) no person or entity guilty of fraudulent
misrepresentation (within the meaning of Section 12(f) of the Securities Act) will be entitled to contribution from any person
or entity who was not guilty of such fraudulent misrepresentation.

 

    	 	11	 

     

    

 

10.         Changes
in Capital Stock. If, and as often as, there is any change in the capital stock of the Company by way of a forward or reverse
stock split, stock dividend, combination or reclassification, or through a merger, consolidation, reorganization or recapitalization,
or by any other means, appropriate adjustment shall be made in the provisions hereof so that the rights and privileges granted
hereby shall continue as so changed.

 

11.         Representations
and Warranties of the Company. The Company represents and warrants to the Investor as follows:

 

(a)          The
execution, delivery and performance of this Agreement by the Company have been duly authorized by all requisite corporate action
and will not violate any provision of law, any order of any court or other agency of government, the Certificate of Incorporation
or Bylaws of the Company or any provision of any indenture, agreement or other instrument to which it or any or its properties
or assets is bound, conflict with, result in a breach of or constitute (with due notice or lapse of time or both) a default under
any such indenture, agreement or other instrument or result in the creation or imposition of any lien, charge or encumbrance of
any nature whatsoever upon any of the properties or assets of the Company or its subsidiaries.

 

(b)          This
Agreement has been duly executed and delivered by the Company and constitutes the legal, valid and binding obligation of the Company,
enforceable in accordance with its terms, subject to any applicable bankruptcy, insolvency or other laws affecting the rights of
creditors generally and to general equitable principles and the availability of specific performance.

 

12.         Rule
144 Requirements. The Company agrees to:

 

(a)          make
and keep current public information about the Company available, as those terms are understood and defined in Rule 144 under the
Securities Act;

 

(b)          use
its best efforts to file with the Commission in a timely manner all reports and other documents required of the Company under the
Securities Act and the Exchange Act; and

 

(c)          furnish
to any holder of Registrable Securities upon request (i) a written statement by the Company as to its compliance with the reporting
requirements of Rule 144 and of the Securities Act and the Exchange Act (at any time after it has become subject to such reporting
requirements), (ii) a copy of the most recent annual or quarterly report of the Company and Current Reports on Form 8-K, as filed
with the Commission, and (iii) such other reports and documents of the Company as such holder may reasonably request to avail itself
of any similar rule or regulation of the Commission allowing it to sell any such securities without registration.

 

13.         Termination.
All of the Company’s obligations to register Registrable Shares under Sections 3, 4 and 5 hereof shall terminate
upon the date on which the Investor holds no Registrable Securities or all of the Registrable Securities are eligible for resale
without volume or manner-of-sale restrictions and without current public information pursuant to Rule 144, as determined by counsel
to the Company pursuant to a written opinion letter to such effect, addressed and reasonably acceptable to the Company’s
transfer agent and the Investor.

 

14.         Miscellaneous.

 

(a)          All
covenants and agreements contained in this Agreement by or on behalf of any of the parties hereto shall bind and inure to the benefit
of the respective successors and assigns of the parties hereto (including without limitation transferees of any Registrable Securities),
whether so expressed or not.

 

    	 	12	 

     

    

 

(b)          All
notices, requests, consents and other communications hereunder shall be in writing and shall be delivered in person, mailed by
certified mail, return receipt requested, postage prepaid, addressed or sent by a nationally recognized overnight courier service:
(i) if to the Company, at 955 Hartman Run Road, Morgantown, WV 26507, Attn: President; and (ii) if to any holder of Registrable
Securities, to such holder at such address as may have been furnished to the Company or its counsel in writing by such holder;
or, in any case, at such other address or addresses as shall have been furnished, in writing to the Company or its counsel (in
the case of a holder of Registrable Securities) or to the holders of Registrable Securities (in the case of the Company) in accordance
with the provisions of this paragraph. Any notice or other communication or deliveries hereunder shall be deemed given and effective
upon actual receipt by the party to whom such notice is required to be given.

 

(c)          This
Agreement shall be governed by and construed under the laws of the State of New York, without giving effect to principles of conflicts
of laws. The Company and Investor (i) agree that any legal suit, action or proceeding arising out of or relating to this Agreement
shall be instituted exclusively in in New York State Supreme Court, County of New York, or in the United States District Court
for the Southern District of New York, (ii) waive any objection which the Company or Investor may have now or hereafter to the
venue of any such suit, action or proceeding, and (iii) irrevocably consent to the jurisdiction of any such federal or state court
in any such suit, action or proceeding. The Company and Investor further agree to accept and acknowledge service of any and all
process which may be served in any such suit, action or proceeding and agree that service of process upon the Company or Investor
mailed by certified mail, return receipt requested, postage prepaid, to, in the case of the Company, the Company’s address,
and in the case of the Investor, to the Investor’s address as set forth on the Company’s books and records, shall be
deemed in every respect effective service of process upon the Company, in any such suit, action or proceeding. THE PARTIES HERETO
AGREE TO WAIVE THEIR RESPECTIVE RIGHTS TO A JURY TRIAL OF ANY CLAIM OR CAUSE OF ACTION BASED UPON OR ARISING OUT OF THIS AGREEMENT
OR ANY DOCUMENT OR AGREEMENT CONTEMPLATED HEREBY.

 

(d)          In
the event of a breach by the Company or by the Investor, of any of their obligations under this Agreement, the Investor or the
Company, as the case may be, in addition to being entitled to exercise all rights granted by law and under this Agreement, including
recovery of damages, will be entitled to specific performance of its rights under this Agreement. The Company and the Investor
agree that monetary damages would not provide adequate compensation for any losses incurred by reason of a breach by it of any
of the provisions of this Agreement and hereby further agrees that, in the event of any action for specific performance in respect
of such breach, it shall waive the defense that a remedy at law would be adequate.

 

(e)          This
Agreement may not be amended or modified without the written consent of the Company and the Investor.

 

(f)          Failure
of any party to exercise any right or remedy under this Agreement or otherwise, or delay by a party in exercising such right or
remedy, shall not operate as a waiver thereof. No waiver shall be effective unless and until it is in writing and signed by the
party granting the waiver.

 

(g)          This
Agreement may be executed in two or more counterparts (including by facsimile or .pdf transmission) each of which shall be deemed
an original, but all of which together shall constitute one and the same instrument. This Agreement, once executed by a party,
may be delivered to the other party hereto by facsimile transmission of a copy of this Agreement bearing the signature of the party
so delivering this Agreement.

 

    	 	13	 

     

    

 

(h)          If
any provision of this Agreement shall be held to be illegal, invalid or unenforceable, such illegality, invalidity or unenforceability
shall attach only to such provision and shall not in any manner affect or render illegal, invalid or unenforceable any other provision
of this Agreement, and this Agreement shall be carried out as if any such illegal, invalid or unenforceable provision were not
contained herein.

 

(i)          This
Agreement constitutes the entire agreement among the Company and the Investor relative to the subject matter hereof and supersedes
in its entirety any and all prior agreements, understandings and discussions with respect thereto.

 

(j)          The
headings of the sections of this Agreement are for convenience and shall not by themselves determine the interpretation of this
Agreement.

 

[Signature Page Follows]

 

    	 	14	 

     

    

 

Signature Page to the Registration Rights Agreement

 

Investors:

 

The Investors set forth on Exhibit A
to the Purchase Agreement have executed a Subscription Agreement with the Company which provides, among other things, that by executing
the Subscription Agreement each Investor is deemed to have executed the REGISTRATION RIGHTS AGREEMENT in all respects and is bound
to purchase the Units set forth in such Subscription Agreement and Exhibit A to the Purchase Agreement.

 

THE COMPANY:

 

PROTEA BIOSCIENCES GROUP, INC.

 

	By: 	 
	Name: Stephen Turner
	Title: Chief Executive Officer

 

Dated:    October __, 2016

 

    	 	15	 

     

    

 

Annex A

 

Plan of Distribution

 

Each selling stockholder
(the “Selling Stockholders”) of the securities and any of their pledgees, assignees and successors-in-interest
may, from time to time, sell any or all of their securities covered hereby on any stock exchange, market or trading facility on
which the securities of the Company are traded or in private transactions.  These sales may be at fixed or negotiated
prices.  A Selling Stockholder may use any one or more of the following methods when selling securities:

 

		·	ordinary brokerage transactions
and transactions in which the broker-dealer solicits purchasers;

 

		·	block trades in which the
broker-dealer will attempt to sell the securities as agent but may position and resell a portion of the block as principal to
facilitate the transaction;

 

		·	purchases by a broker-dealer
as principal and resale by the broker-dealer for its account;

 

		·	an exchange distribution
in accordance with the rules of the applicable exchange;

 

		·	privately negotiated transactions;

 

		·	settlement of short sales
entered into after the effective date of the registration statement of which this prospectus is a part;

 

		·	in transactions through broker-dealers
that agree with the Selling Stockholders to sell a specified number of such securities at a stipulated price per security;

 

		·	through the writing or settlement
of options or other hedging transactions, whether through an options exchange or otherwise;

 

		·	a combination of any such
methods of sale; or

 

		·	any other method permitted
pursuant to applicable law.

 

The Selling Stockholders may also sell securities
under Rule 144 under the Securities Act, if available, rather than under the prospectus contained in a Registration Statement.

 

Broker-dealers engaged
by the Selling Stockholders may arrange for other brokers-dealers to participate in sales.  Broker-dealers may receive
commissions or discounts from the Selling Stockholders (or, if any broker-dealer acts as agent for the purchaser of securities,
from the purchaser) in amounts to be negotiated, but, except as set forth in a supplement to this Prospectus, in the case of an
agency transaction not in excess of a customary brokerage commission in compliance with FINRA Rule 2440; and in the case of a principal
transaction a markup or markdown in compliance with FINRA IM-2440.

 

In connection with
the sale of the securities or interests therein, the Selling Stockholders may enter into hedging transactions with broker-dealers
or other financial institutions, which may in turn engage in short sales of the securities in the course of hedging the positions
they assume.  The Selling Stockholders may also sell securities short and deliver these securities to close out their
short positions, or loan or pledge the securities to broker-dealers that in turn may sell these securities.  The Selling
Stockholders may also enter into option or other transactions with broker-dealers or other financial institutions or create one
or more derivative securities which require the delivery to such broker-dealer or other financial institution of securities offered
by this prospectus, which securities such broker-dealer or other financial institution may resell pursuant to this prospectus (as
supplemented or amended to reflect such transaction).

 

    	 	16	 

     

    

 

The Selling Stockholders
and any broker-dealers or agents that are involved in selling the securities may be deemed to be “underwriters” within
the meaning of the Securities Act in connection with such sales.  In such event, any commissions received by such broker-dealers
or agents and any profit on the resale of the securities purchased by them may be deemed to be underwriting commissions or discounts
under the Securities Act.  Each Selling Stockholder has informed the Company that it does not have any written or oral
agreement or understanding, directly or indirectly, with any person to distribute the securities. In no event shall any broker-dealer
receive fees, commissions and markups which, in the aggregate, would exceed eight percent (8%).

 

The Company is required
to pay certain fees and expenses incurred by the Company incident to the registration of the securities.  The Company
has agreed to indemnify the Selling Stockholders against certain losses, claims, damages and liabilities, including liabilities
under the Securities Act.

 

Because Selling Stockholders
may be deemed to be “underwriters” within the meaning of the Securities Act, they will be subject to the prospectus
delivery requirements of the Securities Act including Rule 172 thereunder.  In addition, any securities covered by this
prospectus which qualify for sale pursuant to Rule 144 under the Securities Act may be sold under Rule 144 rather than under this
prospectus. The Selling Stockholders have advised us that there is no underwriter or coordinating broker acting in connection with
the proposed sale of the resale securities by the Selling Stockholders.

 

We agree to keep the
prospectus effective until the earlier of (i) the date on which the securities may be resold by the Selling Stockholders without
registration and without regard to any volume or manner-of-sale limitations and without current public information by reason of
Rule 144 under the Securities Act or any other rule of similar effect or (ii) all of the securities have been sold pursuant to
this prospectus or Rule 144 under the Securities Act or any other rule of similar effect.  The resale securities will
be sold only through registered or licensed brokers or dealers if required under applicable state securities laws. In addition,
in certain states, the resale securities covered hereby may not be sold unless they have been registered or qualified for sale
in the applicable state or an exemption from the registration or qualification requirement is available and is complied with.

 

Under applicable rules
and regulations under the Exchange Act, any person engaged in the distribution of the resale securities may not simultaneously
engage in market making activities with respect to the common stock for the applicable restricted period, as defined in Regulation
M, prior to the commencement of the distribution.  In addition, the Selling Stockholders will be subject to applicable
provisions of the Exchange Act and the rules and regulations thereunder, including Regulation M, which may limit the timing of
purchases and sales of securities of the common stock by the Selling Stockholders or any other person.  We will make
copies of this prospectus available to the Selling Stockholders and have informed them of the need to deliver a copy of this prospectus
to each purchaser at or prior to the time of the sale (including by compliance with Rule 172 under the Securities Act).

  

    	 	17

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