Document:

Second Amendment to the Cardinal Health 401K Savings Plan

 Exhibit 4.7 
 SECOND AMENDMENT 
 TO THE 
 CARDINAL HEALTH 401(K) SAVINGS PLAN 
 (As amended and restated effective January 1, 2006) 
 Background
Information 
 A. Cardinal Health, Inc. (“Cardinal Health”) previously adopted and currently maintains the Cardinal Health
401(k) Savings Plan (the “Plan”), for the benefit of employees of Cardinal Health and its subsidiaries and affiliates. 
 B.
Section 12.02 of the Plan permits the amendment of the Plan at any time. 
 C. The Cardinal Health, Inc. Financial Benefit Plans Committee
(the “Committee”) is authorized to approve the amendment of the Plan and documents related to the Plan’s administration. 
 D.
The Committee desires to amend the Plan to provide for the acceptance of rollovers of participant loans into the Plan, and, for employees previously participating in the Viasys Healthcare Inc. Retirement and Savings Plan (the “Viasys
Plan”), to provide for the acceptance of the existing provisions of such loans notwithstanding that provisions relating to the permissible term of such Viasys Plan loans, the number of loans per participant maintained by participants in the
Viasys Plan or any other loan provisions of the Viasys Plan conflict with the loan provisions currently in place for the Plan. 
 E. The
Committee also desires to amend the Plan to clarify the application of certain special vesting provisions applicable upon job elimination by the relocation and elaboration of such provisions within the Plan document. 
 F. The Committee also desires to amend the Plan to allow non-spouse beneficiaries of participants in the Plan to elect a direct rollover of Plan benefits to
an individual retirement account or individual retirement annuity as permitted under and in conformance with the provisions of Internal Revenue Code Section 402(c)(11), pursuant to the Pension Protection Act of 2006. 
 Amendment of the Cardinal Health 401(k) Savings Plan 
 The Plan is hereby amended as set forth below effective July 1, 2007, unless some other effective date is specified herein. 

1. The first paragraph of Section 3.12 of the Plan is hereby amended by adding a new fourth sentence to read as follows: 
 Subject to the approval of the Administrative Committee, such rollover amounts may also include any outstanding participant loans from
another plan qualified under either Code Section 401(a) or 403(a) rolled over to the Plan in kind, provided such other qualified plan permits rollover of loans in kind. 

 2. Section 4.01 of the Plan and Schedule V of the Plan are hereby amended by removing paragraph F from
Schedule V of the Plan and inserting such former paragraph F of Schedule V into Section 4.01 of the Plan as new paragraph C. of such Section. 
 3. The first sentence of such new Section 4.01C of the Plan, as modified herein, is hereby further amended to read as follows: 
 Non-highly Compensated Employees Subject to Job Elimination. A non-highly Compensated Employee who has completed one full year of Service but less than three years of Service and is terminated from
employment under the terms of a designated reduction in force, a divestiture or designated layoff, shall receive additional vesting service hereunder as provided below. 
 4. Section 6.05B.ii of the Plan, defining “Eligible Retirement Plan,” is hereby amended by adding a new sentence to the end thereof to read as follows: 
 Effective July 1, 2007, subject to the provisions of Code Section 402(c)(11), Eligible Retirement Plan shall include an individual
retirement plan described in Code Section 402(c)(8)(B)(i) or (ii) that is established for the purpose of receiving a distribution on behalf of an individual who is a designated Beneficiary of a deceased Employee or former Employee and who
is not the surviving Spouse of such deceased Employee or former Employee, provided that the distribution is made in the form of a direct trustee-to-trustee transfer to such individual retirement plan. 
 5. Section 6.05B.iii of the Plan, defining “Distributee,” is hereby amended by adding a new sentence to the end thereof to read as follows:

 Effective July 1, 2007, a Beneficiary of a deceased Employee or former Employee other than the Employee’s or former
Employee’s surviving Spouse is a Distributee for the limited purpose identified in Section 6.05B.ii above. 
 6. Schedule V of the
Plan is hereby further amended by adding a new paragraph F thereto to read as follows in its entirety: 
 F. Special Rules
Regarding Former Participants in the Viasys Healthcare Inc. Retirement and Savings Plan. A Participant employed by Viasys Healthcare Inc. (“Viasys”) on July 1, 2007 and electing to rollover in kind to the Plan a loan or loans
previously maintained under the Viasys Healthcare Inc. Retirement and Savings Plan (the “Viasys Plan”) that conformed to the provisions of Code Section 72(p) shall be permitted to rollover such loan(s) to the Plan in kind pursuant to
Section 3.12 of the Plan, notwithstanding the fact that the term of such loan(s), the total number of loans maintained by the Participant under the Viasys Plan or other provisions of the Viasys Plan relating to the maintenance of participant
loans do not conform to the loan provisions currently in place under the Plan. Loans rolled into the Plan in kind from the Viasys Plan shall continue to be governed by such repayment, availability and other such provisions as were in place at the
inception of such loans under the Viasys Plan. Any new loans by Participants formerly employed by Viasys shall be governed by the terms of the Plan and by the loan policies and procedures established by the Administrative Committee. 

 7. Schedule I of the Plan, as amended, is hereby amended by the addition of the following Related Employer
and Effective Date of Participation in the appropriate alphabetical location therein: 
 Viasys Healthcare Inc. 
 (Effective September 17, 2007) 
 8. All other provisions of the Plan shall remain in full force and effect. 
  

			
	CARDINAL HEALTH, INC.
		
	BY:	 	         /s/ Susan Nelson

		
	ITS:	 	         Sr. V.P. Total Rewards

		
	DATE:	 	                 8/22/07Third Amendment to the Cardinal Health 401K Savings Plan

 Exhibit 4.8 
 THIRD AMENDMENT 
 TO THE 
 CARDINAL HEALTH 401(K) SAVINGS PLAN 
 (As amended and restated effective January 1, 2006) 
 Background
Information 
 A. Cardinal Health, Inc. (“Cardinal Health”) previously adopted and currently maintains the Cardinal Health
401(k) Savings Plan (the “Plan”), for the benefit of employees of Cardinal Health and its subsidiaries and affiliates. 
 B.
Section 12.02 of the Plan permits the amendment of the Plan at any time. 
 C. The Cardinal Health, Inc. Financial Benefit Plans Committee
(the “Committee”) is authorized to approve the amendment of the Plan and documents related to the Plan’s administration. 
 D.
The Committee desires to amend the Plan to clarify the Plan’s loan procedures applicable to former participants under the Plan. 
 Amendment of the Cardinal Health 401(k) Savings Plan 
 The Plan is hereby amended as set forth below
effective as of January 1, 2007. 
 1. The first paragraph of Section 6.06A of the Plan regarding loans to Plan participants is hereby
clarified by adding a new last sentence to read as follows: 
 Notwithstanding the foregoing, a loan may be made available to a
Former Participant who remains an active employee on an Employer’s payroll. 
 2. All other provisions of the Plan shall remain in full
force and effect. 
  

			
	CARDINAL HEALTH, INC.
		
	BY:	 	         /s/ Joan Kelly

		
	ITS:	 	         Sr. VP Total Rewards

		
	DATE:	 	             11/16/07Fourth Amendment to the Cardinal Health 401K Savings Plan

 Exhibit 4.9 
 FOURTH AMENDMENT TO THE 
 CARDINAL HEALTH 401(K)
SAVINGS PLAN 
 (As amended and restated effective January 1, 2006) 
 Background Information 
 A. Cardinal Health, Inc. (“Cardinal Health”) previously adopted and currently maintains the Cardinal Health 401(k) Savings Plan (the “Plan”), for the benefit of employees of Cardinal Health and its subsidiaries and
affiliates. 
 B. The Cardinal Health, Inc. Financial Benefit Plans Committee (the “Committee”) is authorized to approve the amendment
of the Plan and documents related to the Plan’s administration in accordance with Section 12.02 of the Plan. 
 C. The Committee
desires to amend the Plan to provide for the acceptance of rollovers of participant loans from employees previously participating in the Enturia, Inc. 401(k) Savings and Retirement Plan. 
 Amendment of the Cardinal Health 401(k) Savings Plan 
 The Plan is hereby amended as set forth below effective as of May 12, 2008. 
 1. Schedule V of the Plan is hereby amended by
adding a new paragraph G thereto reading as follows: 
 G. Special Rules Regarding Former Participants in the Enturia, Inc.
401(k) Savings and Retirement Plan. A Participant employed by Enturia, Inc. or any of its affiliated entities (collectively, “Enturia”) immediately prior to the acquisition of the assets of Enturia by the Employer and that immediately
thereafter becomes an employee of an Employer, may elect to rollover in kind to the Plan one or more participant loans previously maintained under the Enturia, Inc. 401(k) Savings and Retirement Plan (the “Enturia Plan”) that conform to
the provisions of Code Section 72(p), notwithstanding the fact that the term of such loan(s), the total number of loans maintained by the Participant under the Enturia Plan or other provisions of the Enturia Plan relating to the maintenance of
participant loans do not conform to the loan provisions currently in place under the Plan. Loans rolled into the Plan in kind from the Enturia Plan shall continue to be governed by such repayment, availability and other provisions as were in place
at the inception of such loans under the Enturia Plan. Any new loans by Participants formerly employed by Enturia shall be governed by the terms of the Plan and by the loan policies and procedures established by the Administrative Committee.

 2. All other provisions of the Plan shall remain in full force and effect. 
  

			
	CARDINAL HEALTH, INC.
		
	BY:	 	         /s/ Joan Kelly

		
	ITS:	 	         Sr. V.P., Total Rewards

		
	DATE:	 	             5-19-08

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