Document:

Exhibit 10.19

 

iSpecimen
Inc.

 

Amendment
to Note Subscription Agreements and Secured Promissory Notes

 

Approved
by the Board of Directors on April 26, 2019

 

This Amendment to
the Note Subscription Agreements and Secured Promissory Notes (this “Amendment”) is made and entered
into and effective as of May 1, 2019, by and among iSpecimen Inc., a Delaware corporation (the “Company”),
and those investors who are holders (the “Note Investors”) of the Company’s Secured Promissory
Notes in the aggregate principal amount of $3,195,000 (as described below).

 

Whereas,
the Company and the Note Investors have previously and separately entered into various Note Subscription Agreements executed at
various times between August 2018 and April 2019 (the “Note Subscription Agreements”), pursuant to which
the Company issued and sold $3,195,000 in aggregate principal amount of Secured Promissory Notes (the “Secured Promissory
Notes”);

 

Whereas,
the Note Subscription Agreements and the Secured Promissory Notes may be amended with the consent of the Company and the holders
of greater than fifty-percent (50%) in principal amount of outstanding Secured Promissory Notes (the “Majority Lenders”
as defined in the Note Subscription Agreements prior to this Amendment);

 

Now,
Therefore, in consideration of the mutual promises and covenants set forth herein,
and for other good and valuable consideration, the receipt of and sufficiency of which are hereby acknowledged, the Company and
the undersigned Note Investors agree as follows:

 

1.            Defined Terms. Except as specifically provided herein, capitalized terms not defined herein shall have the
meanings ascribed to them in the Note Subscription Agreements and the Secured Promissory Notes.

 

2.            Amendments to the Note Subscription Agreements and the Secured Promissory Notes. The Note Subscription Agreements
and the Secured Promissory Notes are hereby amended as follows: 

 

		A.	Note Subscription Agreement: Section 1.2, Initial Closing Date and Serial Closings

 

		Delete:	“A minimum capital requirement
for the initial closing shall be $500,000.00 (the “Initial Closing”). The Initial Closing shall take
place as soon as practicable but no later than September 30, 2018 (the “Closing Date”) following satisfaction
of the conditions set forth in Section 6 below. At any time, and from time to time, during the one-year period immediately following
the Initial Closing, the Company may, at one or more additional closings (each a “Closing”), offer,
sell and issue additional Notes to Investors upon the same terms and conditions hereof, provided that in no event shall the
Company issue more than $4,000,000 in aggregate principal amount of Notes across all Closings, including at the Initial Closing.
Additional Closings may be held at the discretion of the Board of Directors, and at each such Closing, any Investor shall execute
an agreement in form and substance similar to this Agreement, and the Company shall issue to such Investor a Note in the amount
of such investment at such additional Closing. Notwithstanding the foregoing, the Board of Directors may extend the period for
additional Closings beyond one-year in its sole discretion.”

 

		Insert:	“A minimum capital requirement
for the initial closing shall be $500,000.00 (the “Initial Closing”). The Initial Closing shall take
place as soon as practicable but no later than September 30, 2018 (the “Closing Date”) following satisfaction
of the conditions set forth in Section 6 below. At any time, and from time to time, during the eighteen (18) month period immediately
following the Initial Closing, the Company may, at one or more additional closings (each a “Closing”),
offer, sell and issue additional Notes to Investors upon the same terms and conditions hereof, provided that in no event shall
the Company issue more than $5,000,000 in aggregate principal amount of Notes across all Closings, including at the Initial
Closing. Additional Closings may be held at the discretion of the Board of Directors, and at each such Closing, any Investor shall
execute an agreement in form and substance similar to this Agreement, and the Company shall issue to such Investor a Note in the
amount of such investment at such additional Closing. Notwithstanding the foregoing, the Board of Directors may extend the period
for additional Closings beyond one-year in its sole discretion.”

 

    	iSpecimen Inc.
Amendment to Note Subscription Agreements and Secured Promissory Notes, April 2019
	Page 1

     

    

 

		B.	Note Subscription Agreement: Section 1.4, Amendment of Notes

 

		Delete:	“This Agreement and the Notes
may be amended, extended, converted, substituted, or otherwise modified on behalf of all holders of Notes issued in connection
with this Note Financing with the written consent or approval of the Company and the holders of at least a majority in aggregate
principal amount of all Notes issued in this Note Financing (the “Majority Lenders”). No individual
Note holder shall have the right to block any corporate action unless acted upon by the Majority Lenders and the Company, as set
forth above. The Notes issued to the undersigned Investor and all other Notes issued by the Company in this Note Financing shall
rank pari passu in all respects (including repayment).”

 

		Insert:	“This Agreement and the Notes
may be amended, extended, converted, substituted, or otherwise modified on behalf of all holders of Notes issued in connection
with this Note Financing with the written consent or approval of the Company and the holders of no less than seventy five percent
(75%) in aggregate principal amount of all Notes issued in this Note Financing (the “Majority Lenders”).
No individual Note holder shall have the right to block any corporate action unless acted upon by the Majority Lenders and the
Company, as set forth above. The Notes issued to the undersigned Investor and all other Notes issued by the Company in this Note
Financing shall rank pari passu in all respects (including repayment).”

 

3.            Effect of Amendment. The parties hereby agree and acknowledge that except as provided in this Amendment, the
Note Subscription Agreements and the Secured Promissory Notes remain in full force and effect, it being the intention of the parties
that this Amendment, the Note Subscription Agreements, and the Secured Promissory Notes, as applicable, be read, construed and
interpreted as one and the same integrated instrument. This Amendment shall automatically take effect when executed, signed and
delivered by those Note Investors holding greater than fifty-percent (50%) in principal amount of the outstanding Secured Promissory
Notes. The undersigned parties hereby acknowledge and agree that, except as provided in this Amendment, the Note Subscription Agreements,
the Secured Promissory Notes, and the respective agreements, covenants and obligations thereunder, are hereby expressly ratified
and confirmed as of the date hereof.

 

4.            Counterparts; Facsimile and Electronic Signatures. This Amendment may be executed in any number of counterparts,
and each such counterpart hereof shall be deemed to be an original instrument, but all such counterparts together shall constitute
a single integrated agreement. For purposes of this Amendment, a document (or signature page thereto) signed and transmitted by
facsimile machine, portable document format, or other electronic means is to be treated as an original document. The signature
of any party on any such document, for purposes hereof, is to be considered as an original signature, and the document transmitted
is to be considered to have the same binding effect as an original signature on an original document. No party may raise the use
of a facsimile machine or other electronic means, or the fact that any signature was transmitted through the use of a facsimile
machine or other electronic means, as a defense to the enforcement of this Amendment.

 

[REST OF PAGE INTENTIONALLY LEFT BLANK
-- SIGNATURE PAGE FOLLOWS]

 

    	iSpecimen Inc.
Amendment to Note Subscription Agreements and Secured Promissory Notes, April 2019
	Page 2

     

    

 

iSpecimen
Inc.

 

Amendment
TO THE

NOTE
SUBSCRIPTION AGREEMENTS and secured promissory notes

 

Approved
by the Board of Directors on April 26, 2019

 

In
Witness Whereof, the parties hereto have executed this Amendment to the Note Subscription Agreements and Secured
Promissory Notes as of the date and year first written above, as an instrument under seal.

 

	 	Company:
	 	 
	 	
        iSpecimen
Inc. 

	 	 
	 	 
	 	By:	/s/ Christopher Ianelli, MD, PhD
	 	 	 
	 	 	Name:	Christopher Ianelli, MD, PhD
	 	 	 	 
	 	 	Title:	Chief Executive Office

 

This
Amendment shall take effect when executed by the Company and those Note Investors holding greater than fifty-percent (50%) in principal
amount of all outstanding Secured Promissory Notes and shall be binding on all other holders of the Secured
Promissory Notes.

 

Note
Investors:

 

	If Entity, Please Print Name of Entity & Title:	 	If Individual, Print Name of Investor:
	 	 	 	 	 
	 	 	 	 	 
	Name of Entity:	 	 	Print Name:	 

 

	 	 	 	 	 
	By:	 	 	By:	 
	 	Signature	 	 	Signature
	 	 	 	 	 
	Title: 	 	 	 	 

 

	Address:	 	 	Address:	 
	 	 	 	 	 
	 	 	 	 	 

 

	 	 	 
	Date: _________________________, 2019	 	Date: ________________________, 2019

 

Principal amount of Notes
held on date above:

 

    
iSpecimen Inc.
Amendment to Note Subscription Agreements and Secured Promissory Notes, April 2019Exhibit 10.20

 

iSpecimen
Inc.

 

Amendment
to Note Subscription Agreements and Secured Promissory Notes

 

Approved
by the Board of Directors on October 25, 2019

 

This Amendment to
the Note Subscription Agreements and Secured Promissory Notes (this “Amendment”) is made and entered
into and effective as of November 15, 2019, by and among iSpecimen Inc., a Delaware corporation (the “Company”),
and those investors who are holders (the “Note Investors”) of the Company’s Secured Promissory
Notes in the aggregate principal amount of $4,945,000 (as described below).

 

Whereas, the
Company and the Note Investors have previously and separately entered into various Note Subscription Agreements executed at various
times between August 2018 and October 2019 (the “Note Subscription Agreements”), pursuant to which the
Company issued and sold $4,945,000 in aggregate principal amount of Secured Promissory Notes (the “Secured Promissory
Notes”);

 

Whereas,
the Note Subscription Agreements and the Secured Promissory Notes may be amended with the consent of the Company and the holders
of greater than seventy-five percent (75%) in principal amount of outstanding Secured Promissory Notes (the “Majority
Lenders” as defined in the Note Subscription Agreements prior to this Amendment);

 

Now, Therefore,
in consideration of the mutual promises and covenants set forth herein, and for other good and valuable consideration, the receipt
of and sufficiency of which are hereby acknowledged, the Company and the undersigned Note Investors agree as follows:

 

1.            Defined Terms. Except as specifically provided herein, capitalized terms not defined herein shall have the
meanings ascribed to them in the Note Subscription Agreements and the Secured Promissory Notes.

 

2.            Amendments to the Note Subscription Agreements and the Secured Promissory Notes. The Note Subscription Agreements
and the Secured Promissory Notes are hereby amended as follows: 

 

		A.	Note Subscription Agreement: Section 1.2, Initial Closing Date and Serial Closings

 

		Delete:	“A minimum capital requirement for the initial closing shall be $500,000.00 (the “Initial
Closing”). The Initial Closing shall take place as soon as practicable but no later than September 30, 2018 (the
 “Closing Date”) following satisfaction of the conditions set forth in Section 6 below. At any time, and
from time to time, during the eighteen (18) month period immediately following the Initial Closing, the Company may, at one or
more additional closings (each a “Closing”), offer, sell and issue additional Notes to Investors upon
the same terms and conditions hereof, provided that in no event shall the Company issue more than $5,000,000 in aggregate principal
amount of Notes across all Closings, including at the Initial Closing. Additional Closings may be held at the discretion of
the Board of Directors, and at each such Closing, any Investor shall execute an agreement in form and substance similar to this
Agreement, and the Company shall issue to such Investor a Note in the amount of such investment at such additional Closing. Notwithstanding
the foregoing, the Board of Directors may extend the period for additional Closings beyond one-year in its sole discretion.”

 

		Insert:	“A minimum capital requirement for the initial closing shall be $500,000.00 (the “Initial
Closing”). The Initial Closing shall take place as soon as practicable but no later than September 30, 2018 (the
 “Closing Date”) following satisfaction of the conditions set forth in Section 6 below. At any time, and
from time to time, during the eighteen (18) month period immediately following the Initial Closing, the Company may, at one or
more additional closings (each a “Closing”), offer, sell and issue additional Notes to Investors upon
the same terms and conditions hereof, provided that in no event shall the Company issue more than $7,000,000 in aggregate principal
amount of Notes across all Closings, including at the Initial Closing. Additional Closings may be held at the discretion of
the Board of Directors, and at each such Closing, any Investor shall execute an agreement in form and substance similar to this
Agreement, and the Company shall issue to such Investor a Note in the amount of such investment at such additional Closing. Notwithstanding
the foregoing, the Board of Directors may extend the period for additional Closings beyond eighteen months in its sole discretion.”

 

    	iSpecimen Inc.
Second Amendment to Note Subscription Agreements and Secured Promissory Notes, November 2019
	Page 1

     

    

 

3.            Effect of Amendment. The parties hereby agree and acknowledge that except as provided in this Amendment, the
Note Subscription Agreements and the Secured Promissory Notes remain in full force and effect, it being the intention of the parties
that this Amendment, the Note Subscription Agreements, and the Secured Promissory Notes, as applicable, be read, construed and
interpreted as one and the same integrated instrument. This Amendment shall automatically take effect when executed, signed and
delivered by those Note Investors holding greater than seventy-five percent (75%) in principal amount of the outstanding Secured
Promissory Notes. The undersigned parties hereby acknowledge and agree that, except as provided in this Amendment, the Note Subscription
Agreements, the Secured Promissory Notes, and the respective agreements, covenants and obligations thereunder, are hereby expressly
ratified and confirmed as of the date hereof.

 

4.            Counterparts; Facsimile and Electronic Signatures. This Amendment may be executed in any number of counterparts,
and each such counterpart hereof shall be deemed to be an original instrument, but all such counterparts together shall constitute
a single integrated agreement. For purposes of this Amendment, a document (or signature page thereto) signed and transmitted by
facsimile machine, portable document format, or other electronic means is to be treated as an original document. The signature
of any party on any such document, for purposes hereof, is to be considered as an original signature, and the document transmitted
is to be considered to have the same binding effect as an original signature on an original document. No party may raise the use
of a facsimile machine or other electronic means, or the fact that any signature was transmitted through the use of a facsimile
machine or other electronic means, as a defense to the enforcement of this Amendment.

 

[REST OF PAGE INTENTIONALLY LEFT BLANK
-- SIGNATURE PAGE FOLLOWS]

 

    	iSpecimen Inc.
Second Amendment to Note Subscription Agreements and Secured Promissory Notes, November 2019
	Page 2

     

    

 

iSpecimen
Inc.

 

Amendment
TO THE

NOTE
SUBSCRIPTION AGREEMENTS and secured promissory notes

 

Approved
by the Board of Directors on October 25, 2019

 

In
Witness Whereof, the parties hereto have executed this Amendment to the Note Subscription Agreements and Secured
Promissory Notes as of the date and year first written above, as an instrument under seal.

 

	 	Company:
	 	 
	 	
        iSpecimen
        Inc. 

        

	 	 
	 	 
	 	By:	/s/ Christopher Ianelli, MD, PhD
	 	 	 
	 	 	Name:	Christopher Ianelli, MD, PhD
	 	 	 	 
	 	 	Title:	Chief Executive Office

 

This Amendment
shall take effect when executed by the Company and those Note Investors holding greater than seventy-five percent (75%) in principal
amount of all outstanding Secured Promissory Notes and shall be binding on all other holders of the Secured Promissory Notes.

 

Note Investors:

 

	If Entity, Please Print Name of Entity & Title:	 	If Individual, Print Name of Investor:
	 	 	 	 	 
	 	 	 	 	 
	Name of Entity:	 	 	Print Name:	 

 

	 	 	 	 	 
	By:	 	 	By:	 
	 	Signature	 	 	Signature
	 	 	 	 	 
	Title: 	 	 	 	 

 

	Address:	 	 	Address:	 
	 	 	 	 	 
	 	 	 	 	 

 

	 	 	 
	Date: _________________________, 2019	 	Date: ________________________, 2019

 

Principal amount of Notes held on date above:

 

    	iSpecimen Inc.
Second Amendment to Note Subscription Agreements and Secured Promissory Notes, November 2019

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00318-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00318-of-00352.parquet"}]]