Document:

Exhibit
10.5

 

AGREEMENT
AND AMENDMENT NO. 3

 

This
AGREEMENT AND AMENDMENT NO. 3 (this “Third Amendment”) is made this 21 day of July, 2015 by and between ORAMED
Ltd., a company incorporated under the laws of the State of Israel, # 513976712 with an address at High-Tech Park 2/4, Givat
Ram, Jerusalem, Israel 93706 (the “Company”), and KNRY, Ltd., a company incorporated under the
laws of the State of Israel, # 513836502 with an address at 2 Elza Street, Jerusalem, Israel 93706 (the “Consultant”).

 

WHEREAS:

 

A.           The Company and the Consultant are parties to the Agreement dated as of July 1, 2008 (the “Original Agreement”),
as amended on July 17, 2013 (the “First Amendment”) and on November 13, 2013 (the “Second Amendment” and
together with the Original Agreement and the First Agreement - the “Employment Agreement”), for services to be provided
by Dr. Miriam Kidron Israeli I.D. number 9665993 (“Miriam”); and

 

B.           The Company and the Consultant wish to amend the Employment Agreement to revise the terms of the Consultant compensation
thereunder.

 

NOW,
THEREFORE, in consideration of the premises and the mutual covenants and agreements herein contained, the parties hereto covenant
and agree as follows:

 

		1.	Amendment
                                         to Section 6. Section 6 of the Original Agreement is hereby amended and restated
                                         in its entirety to read as follows:

 

	 

                              
	“2.1	Compensation.
    Effective from July 2015 (inclusive), the Company shall pay to the Consultant in consideration for the performance of the
    Consulting Services, a gross monthly amount of 63,600 + VAT (approximately $16,650) (the “Consideration”),
    subject to the receipt by the Company of an invoice from the Consultant.  Each of the Consultant and Miriam hereby
    declares that neither of them has, nor shall have in the future, any claims or demands in respect of amounts paid prior to
    May 2008.”

 

		2.	Ratification.
                                         As amended hereby, the Employment Agreement is ratified and confirmed and all
                                         other terms and conditions remain in full force and effect.

 

[Signature
page follows.]

 

     

     

    

 

IN
WITNESS WHEREOF the parties hereto have executed this Third Amendment effective as of the date and year first above written.

 

	ORAMED
    LTD.	 	KNRY
    LTD.
		 	
	 Per:  /s/
    Yifat Zommer                                   	 	/s/
    Nadav Kidron, /s/ Miriam Kidron
	 

        
	 	           KNRY
    LTD.
	Name: Yifat
    Zommer                                       	 	Name: Nadav
    Kidron, Miriam Kidron
	 	 	 
	Title:   Chief
    Financial Officer and Secretary	 	 

 

 

 

 

-2-Exhibit 10.12

 

Second Amendment to Employment Agreement

 

This Second Amendment to the Employment Agreement
(this “Second Amendment”) is entered into as of this 17st day of July 2013, by and between Yifat Zommer,
an individual residing at Rehovot, Israel (the “Executive”), and ORAMED Ltd., a company incorporated
under the laws of the State of Israel, with an address at Hi-Tech Park 2/5 Givat Ram, Jerusalem, Israel 91390 (the ”Company”).

 

WHEREAS,
the Company and the Executive entered into an Employment Agreement, dated as of April 19, 2009 (the “Original Agreement”),
which was amended on August 31st, 2009 (the "First Amendment" and together - the “Employment
Agreement”); and

 

WHEREAS, Company
and the Executive desire to amend some of terms and conditions of the Employment Agreement.

 

NOW, THEREFORE,
the Company and the Executive agree as follows:

 

1.            In Section 2.1(a) - Salary of the Original Agreement the following paragraph is hereby added:

 

As of July 1st, 2013, the Executive shall be
entitled to a gross monthly salary of NIS 31,460 (the “Salary”).

 

2.            Except for the changes and/or additions stated herein, all the other terms of the Employment Agreement shall remain valid
and bind the parties without any change. In the case of a contradiction between the provisions of this Second Amendment and the
provisions of the Employment Agreement, the provisions of this Second Amendment shall prevail. Without limiting the generality
of the foregoing, the term “Agreement” as used in the Employment Agreement shall be deemed to be the Employment Agreement
as amended by this Amendment.

IN WITNESS WHEREOF, the parties have executed this Second Amendment to Employment Agreement as of the date first written above.

  

	 	Oramed Ltd.
	 	 
	 	/s/ Nadav Kidron
	 	Nadav Kidron, CEO
	 	 
	 	/s/ Yifat Zommer
	 	Yifat ZommerExhibit 10.13

 

Third Amendment to Employment Agreement

 

This Third Amendment to the Employment Agreement
(this “Third Amendment”) is entered into as of this 21 day of July 2015, by and between Yifat
Zommer, an individual residing at Rehovot, Israel (the “Executive”), and ORAMED Ltd., a company
incorporated under the laws of the State of Israel, with an address at Hi-Tech Park 2/4 Givat Ram, Jerusalem, Israel 91390 (the
“Company”).

 

WHEREAS, the Company and the
Executive entered into an Employment Agreement, dated as of April 19, 2009 (the “Original Agreement”), which
was amended on August 31, 2009 (the "First Amendment") and on July 17, 2013 (the "Second Amendment"
and together with the Original Agreement and the First Agreement - the “Employment Agreement”); and

 

WHEREAS, Company
and the Executive desire to amend some of terms and conditions of the Employment Agreement.

 

NOW, THEREFORE,
the Company and the Executive agree as follows:

 

1.            In Section 2.1(a) - Salary of the Original Agreement, the following paragraph is hereby added:

 

As of July 1st,
2015, the Executive shall be entitled to a gross monthly salary of NIS 33,347 (the “Salary”).

2.            Except
for the changes and/or additions stated herein, all the other terms of the Employment Agreement shall remain valid and bind
the parties without any change. In the case of a contradiction between the provisions of this Third Amendment and
the provisions of the Employment Agreement, the provisions of this Third Amendment shall prevail. Without limiting the
generality of the foregoing, the term “Agreement” as used in the Employment Agreement shall be deemed to be the
Employment Agreement as amended by this Amendment.

IN WITNESS WHEREOF, the parties have executed this Third Amendment to Employment Agreement as of July 21st,
2015.

  

	 	Oramed Ltd.
	 	 
	 	/s/ Nadav Kidron
	 	Nadav Kidron, CEO
	 	 
	 	/s/ Yifat Zommer
	 	Yifat ZommerExhibit
10.22

 

AGREEMENT
AND AMENDMENT NO. 2

 

This
AGREEMENT AND AMENDMENT NO. 2 is made this 1st day of April 2015, and effective as of January 1, 2015, by and between ORAMED
PHARMACEUTICALS INC., a Delaware corporation with a mailing address at Hi-Tech Park 2/4 Givat Ram, Jerusalem 91390 Israel
(the “Company”), and Michael Berelowitz, M.D., with
an address 415 East 37th Street New York, NY 10016 (“Berelowitz”).

 

WHEREAS:

 

	A.	The Company and Berelowitz are parties to the Agreement dated as of November
26, 2013, as amended on July 16, 2014 (together, the “Original Agreement”); and
	 	 
	B.	The Company and Berelowitz wish to amend the Original Agreement to extend
the term thereof for an additional twelve months.

 

NOW,
THEREFORE, in consideration of the premises and the mutual covenants and agreements herein contained, the parties hereto covenant
and agree as follows:

		1.	Amendment
                                         to Section 1.2. Section 1.2 of the Original Agreement is hereby amended and restated
                                         in its entirety to read as follows:

		“2.1	Term.
                                         Unless terminated earlier in accordance with the provisions hereof, the term of engagement
                                         under this Agreement shall commence on January 1, 2015 (the “Effective Date”)
                                         and shall continue for a period of twelve months (the “Term”).”
                                         

		2.	Ratification.
                                         As amended hereby, the Original Agreement is ratified and confirmed and all other terms
                                         and conditions remain in full force and effect.

 

[Signature
page follows.]

 

     

    
	 	-2-	 

 

    

 

IN
WITNESS WHEREOF the parties hereto have executed this Agreement and Amendment No. 2 effective as of the date and year first above
written.

 

	ORAMED
    PHARMACEUTICALS INC.	 	 
	 	 	 	 
	Per:	/s/
Nadav Kidron, /s/ Yifat Zommer
	 	/s/
    Michael Berelowitz
	 	 	 	MICHAEL
BERELOWITZ M.D.

	Name:	Nadav
    Kidron / Yifat Zommer	 	 
	 	 	 	 
	Title:	Chief
    Executive Officer / CFOExhibit 10.25

 

Amendment to Employment Agreement

 

This Amendment to the Employment Agreement
(this “Amendment”) is entered into as of this 21 day of July 2015, by and between Joshua
Hexter, an individual residing at Jerusalem, Israel (the “Executive”), and ORAMED Ltd., a company
incorporated under the laws of the State of Israel, with an address at Hi-Tech Park 2/4 Givat Ram, Jerusalem, Israel 91390 (the
“Company”). 

 

WHEREAS, the Company and the
Executive entered into an Employment Agreement, dated as of April 15, 2013 (the “Original Agreement”); and

 

WHEREAS, Company
and the Executive desire to amend some of terms and conditions of the Original Agreement.

 

NOW, THEREFORE,
the Company and the Executive agree as follows:

 

1.            In Section 2.1(a) - Salary of the Original Agreement the following paragraph is hereby added:

 

As of July 1st,
2015, the Executive shall be entitled to a gross monthly salary of NIS 40,810 (the “Salary”).

2.            Except for the changes and/or additions stated herein, all the other terms of the Original Agreement shall remain valid
and bind the parties without any change. In the case of a contradiction between the provisions of this Amendment and the provisions
of the Original Agreement, the provisions of this Amendment shall prevail. Without limiting the generality of the foregoing, the
term “Agreement” as used in the Employment Agreement shall be deemed to be the Employment Agreement as amended by
this Amendment.

 

IN WITNESS WHEREOF, the parties have executed this Amendment to Employment Agreement as of July 21st,
2015.

  

	 	Oramed Ltd.
	 	 
	 	/s/ Nadav Kidron
	 	Nadav Kidron, CEO
	 	 
	 	/s/ Joshua Hexter
	 	Joshua Hexter

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