Document:

Assignment and Assumption Agreement

 EXHIBIT 10.1 
  
 ASSIGNMENT AND ASSUMPTION AGREEMENT 
  
 THIS ASSIGNMENT and ASSUMPTION AGREEMENT (this “Assignment”) is entered into between R. Allen Stanford
(hereinafter “RAS”) and Stanford International Bank Limited, a corporation organized and existing under the laws of Antigua and Barbuda, (hereinafter “SIBL”): 
  
 RECITALS: 
  
 WHEREAS, pursuant to those certain Securities Purchase Agreements, dated as of October 16, 2002 and April 30, 2003 (the
“Purchase Agreements”), between Stanford Venture Capital Holdings, Inc. (“SVCH”) and Health Systems Solutions, Inc. (the “Issuer”), SVCH acquired certain securities of the Issuer and was granted certain ancillary rights
in connection with such securities; 
  
 WHEREAS, pursuant to that
certain Loan and Security Agreement, dated as of July 6, 2004, as amended (the “Loan Agreement”), between SVCH and Healthcare Quality Solutions, Inc. (a subsidiary of Issuer), SVCH extended credit and made other financial accommodations to
the Issuer, and in consideration thereof the Issuer granted to SVCH a security interest in certain personal property in order to secure the obligations of Issuer under the Loan Agreement; 
  
 WHEREAS, as a result of its entry into the Purchase Agreement and Loan Agreements, SVCH acquired certain intangible personal
property interests as more particularly set forth on Schedule “A” attached hereto and made a part hereof (collectively, the “Rights”). 
  
 WHEREAS, pursuant to an Assignment and Assumption Agreement (“Assignment Agreement”), effective as of November 29, 2004, between SVCH and RAS,
SVCH assigned all of its right, title and interest in and to the Rights to RAS and, as a result, RAS is the owner and holder of the Rights; 
  
 WHEREAS, RAS has determined that it is in his best interests to assign, transfer and deliver unto SIBL all of his rights, title, and interest in and to
the Rights subject to and on the terms and conditions herein; and 
  
 WHEREAS, SIBL desires to acquire the ownership of the Rights. 
  
 NOW THEREFORE, in consideration of the mutual promises herein made, the mutual benefits to be derived from this Assignment, and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties
hereto represent, warrant, covenant and agree as follows: 
  
 1.
Recitals. The recitals set forth above are true and accurate and are hereby incorporated by reference. 
  

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 2. Assignment of Rights. RAS (the “Assignor”) hereby grants, assigns, transfers and
delivers to SIBL, on an “AS IS” basis, all of his respective rights, title, and interest in and to the Rights including, without limitation, the rights with respect to the payment of all amounts arising from the Rights and interest that
accrues thereon after the date hereof. The assignment provided for herein shall be without recourse to the Assignor. The Assignor also hereby assigns, grants, transfers and delivers to SIBL any and all related rights and benefits that he had as
holder of the Rights or related to or in connection with the Rights including without limitation as a result of or arising pursuant to any statue, law or regulation, the organization documents of the Issuer, or pursuant to any other agreements,
documents or certificates, including without limitation, any and all described in Schedule “A” attached hereto. 
  
 3. Assumption of Rights. Upon the execution and delivery of this Assignment to SIBL, SIBL shall, as of the date hereof, succeed to all of the
Assignor’ right, title and interest in and to the Rights. SIBL for itself and its successors and assigns, hereby accepts the foregoing Assignment and agrees to assume, fulfill, and perform all obligations of the Assignor under and by virtue of
the Rights hereby assigned, which arise on or after the effective date of this Assignment, and does hereby agree to defend, indemnify and hold harmless the Assignor from any liability, damages, causes of actions, expenses and attorneys’ fees
incurred by any of the Assignor by reason of the failure of SIBL to fulfill, perform and discharge all of the obligations of the Assignor under and by virtue of the Rights assigned hereunder, which arise on or after the effective date of this
Assignment; provided, however, that the Assignor shall indemnify and hold SIBL harmless from and against any claims by any third party in respect of any matter or circumstance arising prior to the effective date of this Assignment. In addition, the
Assignor shall remain liable for all of his respective obligations or any other matter relating to the Rights which arose prior to the effective date of this Assignment (“Pre-Assignment Obligations”), and the Assignor shall defend,
indemnify and hold SIBL and its successors and assigns harmless from any and all claims, losses, damages, liabilities, causes of action, expenses and attorney’s fees incurred by SIBL arising from: (i) any Pre-Assignment Obligation and/or (ii)
any false or inaccurate representation or the breach of any representation contained herein. 
  
 4. Representations of the Assignor. The Assignor represents and warrants to SIBL as follows: 
  
 a. That, as of the date hereof, the Assignor has full right and authority to sell and transfer the Rights to SIBL, and that the Rights have not been
pledged, encumbered or previously transferred in whole or in part. 
  
 b. That the Rights are assignable by the Assignor without any consent of any third parties and this assignment of Rights will not cause any default in the performance of any of the terms, covenants, conditions or agreements pertaining to
the ownership of the Rights. 
  
 c. That the Rights are valid and
enforceable and have not been altered, modified or amended and the Assignor is not in (or with the passage of time will be in) default in the performance of any of the terms, covenants, conditions or agreements required of him pursuant to the
ownership of the Rights. 
  

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 5. Further Assurances. The Assignor hereby agrees to take all actions, and execute, acknowledge
and deliver all such instruments (including, without limitation, any stock powers, assignments, allonges and any other conveyance documents) as may be necessary to assure SIBL the rights intended to be provided to SIBL pursuant to this Assignment,
including, without limitation, holding for the account of, and promptly remitting to, SIBL any and all amounts the Assignor receives by virtue of his ownership of the Rights on or after the date hereof. 
  
 6. Miscellaneous. This Assignment shall be governed by and construed
in accordance with the laws of the State of Florida. The venue of any litigation arising under this Assignment shall be Miami-Dade County, Florida and the parties hereto consent to the jurisdiction of the Circuit Court of Dade County, Florida in any
litigation arising hereunder. In the event of any such litigation, the prevailing party shall be entitled to its reasonable costs and attorneys’ fees. This Assignment may be executed in any number of counterparts, each of which shall be an
original, but all of which together shall constitute one instrument. Any oral representations or modifications concerning this Assignment shall be of no force and effect excepting a modification in writing signed by each party hereto. Subject to the
provisions hereof, this Assignment shall be binding upon and inure to the benefit of and be enforceable by the parties hereto, and their successors and assignees. 
  
 [Signatures Begin on Following Page] 
  

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 IN WITNESS WHEREOF, the parties have caused this Assignment to be effective as of November 30, 2004.

  
 AGREED TO AND ACCEPTED: 
  

	
	R. Allen Stanford
	
	 /s/ R. Allen Stanford

	
	Stanford International Bank Limited
	
	 /s/ James M. Davis

	 James M. Davis
 Chief Financial
Officer

  

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 SCHEDULE “A” 
  
 Issuer: Health Systems Solutions, Inc. 
  
 The “Rights” consist of all of the right, title and interest of the Assignors, in existence as of the execution date of this Assignment in and to: 

 

	 	(1)	8,978,177 shares of the common stock of the Issuer. 

  

	 	(2)	Loan and Security Agreement, dated July 6, 2004, by and between Healthcare Quality Solutions, Inc. (subsidiary of Issuer) and SVCH. 

  

	 	(3)	Revolver Promissory Note, dated July 6, 2004, in the principal amount of $1,600,000 executed by Healthcare Quality Solutions, Inc. in favor of SVCH. 

  

	 	(4)	Any liens or security interests under Article 9 of the Uniform Commercial Code granted by the Issuer in favor of any of the Assignors or encumbering any of its assets; any statutory
liens or other consensual liens against the Issuer or any of its assets; any claims or choses in action, whether in tort or contract, against the Issuer or any of its assets; and any other equity interests in the Issuer held by any of the Assignors.

  

 -5-Form of Award Agreement for Incentive Stock Option

 EXHIBIT 10.1 
  
 NATIONAL INTERSTATE CORPORATION 
 INCENTIVE STOCK OPTION AGREEMENT 
  
 This Agreement (the “Agreement”) is made as of             , 20     (the “Date of Grant”) by and
between National Interstate Corporation, an Ohio corporation (the “Company”) and              (the “Optionee”). 
  
 1. Grant of Option Right. Subject to and upon the terms, conditions
and restrictions set forth in this Agreement and in the Company’s Long Term Incentive Plan (the “Plan”), the Company hereby grants to the Optionee as of the Date of Grant an option (the “Option Right”) to purchase
             Common Shares, at the price of
$            .             per share (the “Option Price”). This Option Right is intended to be an
“incentive stock option” within the meaning of that term under Section 422 of the Code, and this Agreement shall be construed in a manner that will enable the Option Right to be so treated. 
  
 2. Vesting and Exercise of Option Right. 
  
 (a) If the Date of Grant occurs on or before April 1 of a calendar year,
unless and until terminated as hereinafter provided, the Option Right will become exercisable to the extent of              of the Common Shares specified in Section 1 on each
subsequent January 1 from the Date of Grant until fully vested on the              anniversary from the first vesting date for as long as the Optionee remains in the continuous
employ of the Company and its Subsidiaries. 
  
 If the Date of
Grant occurs after April 1 of a calendar year, unless and until terminated as hereinafter provided, the Option Right will become exercisable to the extent of              of the
Common Shares specified in Section 1 beginning twelve months from the following January 1 until fully vested on the              anniversary from the first vesting date for as long
as the Optionee remains in the continuous employ of the Company and its Subsidiaries. 
  
 The Option Right will become immediately exercisable in full if while the Optionee is in the employ of the Company and its Subsidiaries: (i) the Optionee dies; (ii) the Optionee becomes permanently disabled (as
determined by the Committee); or (iii) a Change in Control occurs. 
  
 Vesting shall cease and the unvested portion of the Option Right shall be forfeited if the Optionee ceases to be continuously employed by the Company and its Subsidiaries prior to the earliest to occur of the following events (i) the
Optionee’s death; (ii) the Optionee’s permanent disability (as determined by the Committee); or (iii) the occurrence of a Change in Control. 
  
 (b) To the extent that the Option Right becomes exercisable in accordance with this Section 2, and unless and until the Option Right terminates as
hereinafter provided, the Optionee may exercise the Option Right in whole or in part from time to time by providing written notice to the Company stating the number of Common Shares for which the Option Right is being exercised and the intended
manner of payment. 

 (c) In the event of death of the Optionee, the person to whom the Option Right was transferred by will or
pursuant to the laws of descent and distribution (pursuant to Section 7) may exercise the Option Right in accordance with Section 2(b) hereof. Such person must provide proof satisfactory to the Committee that the Option Right was transferred to him.

  
 3. Payment of Option Price. The Option Price is payable
in cash or check payable to the order of the Company. 
  
 4.
Termination of Option Right and Right to Exercise. The Option Right will terminate and may no longer be exercised on the earliest of the following dates: 
  

(a) Ninety days after the Optionee ceases to be an employee of the Company and its Subsidiaries for a reason other than his death or permanent
disability (as determined by the Committee); or 
  
 (b) Ten years
from the Date of Grant. 
  
 5. Delivery of Common Shares.

  
 (a) Subject to the terms and conditions of this
Agreement, the Company shall deliver Common Shares to the Optionee as soon as administratively practicable following the date the Optionee exercises the Option Right in accordance with Section 2 hereof and makes full payment to the Company of the
Option Price. The Optionee shall not possess any incidents of ownership (including, without limitation, dividend and voting rights) in the Common Shares until such Common Shares have been delivered to the Optionee in accordance with this Section 5.

  
 (b) In the event of an exercise of an Option Right by a person
other than the Optionee in accordance with Section 7, the Company shall deliver Common Shares in the same manner as set forth in Section 5(a). 
  
 6. Mandatory Notice of Disqualifying Disposition. Without limiting any other provisions hereof, the Optionee hereby agrees that if the
Optionee disposes (whether by sale, exchange, gift or otherwise) of any of the Common Shares delivered upon exercise of the Option Right within two years of the Date of Grant or within one year after the transfer of such share or shares to the
Optionee, the Optionee shall notify the Company of such disposition in writing within thirty days from the date of such disposition. Such written notice shall state the principal terms of such disposition and the type and amount of the consideration
received for such share or shares by the Optionee in connection therewith. 
  
 7. Transferability. The Option Right may not be sold, exchanged, assigned, transferred, pledged, encumbered or otherwise disposed of by the Optionee; provided, however, that the Optionee’s
rights with respect to such Option Right may be transferred by will or pursuant to the laws of descent and distribution. Any purported transfer or encumbrance in violation of the provisions of this Section 7 shall be void, and the other party to any
such 
  

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 purported transaction shall not obtain any rights to or interest in such Option Right. The Option Right may be exercised,
during the lifetime of the Optionee, only by the Optionee, or in the event of his legal incapacity, by his guardian or legal representative acting on behalf of the Optionee in a fiduciary capacity under state law and court supervision. 

 
 8. Continuous Employment. For purposes of this Agreement,
the continuous employment of the Optionee with the Company and its Subsidiaries shall not be deemed to have been interrupted, and the Optionee shall not be deemed to have ceased to be an employee of the Company and its Subsidiaries, by reason of the
transfer of his employment among the Company and its Subsidiaries or a leave of absence approved by the Committee. 
  
 9. No Employment Contract. Nothing contained in this Agreement shall confer upon the Optionee any right with respect to continuance of employment
by the Company and its Subsidiaries, nor limit or affect in any manner the right of the Company and its Subsidiaries to terminate the employment or adjust the compensation of the Optionee. 
  
 10. Taxes and Withholding. To the extent that the Company shall be
required to withhold any federal, state, local or other taxes in connection with Common Shares obtained upon the exercise of the Option Right, and the amounts available to the Company for such withholding are insufficient, it shall be a condition to
the delivery of such Common Shares that the Optionee shall pay such taxes or make provisions that are satisfactory to the Company for the payment thereof. The Optionee may elect, on or before the date of exercise, to satisfy all or any part of any
such withholding obligation by surrendering to the Company a portion of the Common Shares that are delivered to the Optionee upon the exercise of the Option Right, and the Common Shares so surrendered by the Optionee shall be credited against any
such withholding obligation at the Market Value per Share of such shares on the date of such exercise. 
  
 11. Compliance with Law. The Company shall make reasonable efforts to comply with all applicable federal and state securities laws and listing
requirements of the Nasdaq National Market System or any national securities exchange. 
  
 12. Adjustments. The Committee may make or provide for such adjustments in the Option Price and in the number and kind of shares of stock covered by this Agreement, as the Committee, in its sole discretion,
exercised in good faith, may determine is equitably required to prevent dilution or enlargement of the Optionee’s rights that otherwise would result from (a) any stock dividend, stock split, combination of shares, recapitalization, or other
change in the capital structure of the Company, (b) any merger, consolidation, spin-off, split-off, spin-out, split-up, reorganization, partial or complete liquidation, or other distribution of assets (including, without limitation, a special
or large non-recurring dividend) or issuance of rights or warrants to purchase securities, or (c) any other corporate transaction or event having an effect similar to any of the foregoing. In the event of any such transaction or event, the
Committee, in its discretion, may provide in substitution for the Option Right such alternative consideration as it may in good faith determine to be equitable in the circumstances and may require in connection therewith the surrender of the Option
Right. 
  
 13. Amendments. Subject to the
terms of the Plan, the Committee may modify this Agreement upon written notice to the Optionee. Any amendment to the Plan shall be deemed to 
  

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 be an amendment to this Agreement to the extent that the amendment is applicable hereto. Notwithstanding the foregoing,
no amendment of the Plan or this Agreement shall adversely affect the substantive rights of the Optionee under this Agreement without the Optionee’s consent. 
  
 14. Severability. In the event that one or more of the provisions of this Agreement shall be invalidated for any
reason by a court of competent jurisdiction, any provision so invalidated shall be deemed to be separable from the other provisions hereof, and the remaining provisions hereof shall continue to be valid and fully enforceable. 
  
 15. Relation to Plan. The Option Right granted under this Agreement
and all the terms and conditions hereof are subject to the terms and conditions of the Plan. This Agreement and the Plan contain the entire agreement and understanding of the parties with respect to the subject matter contained in this Agreement,
and supersede all prior communications, representations and negotiations in respect thereto. In the event of any inconsistency between the provisions of this Agreement and the Plan, the Plan shall govern. Capitalized terms used herein without
definition shall have the meanings assigned to them in the Plan. The Committee acting pursuant to the Plan, as constituted from time to time, shall, except as expressly provided otherwise herein, have the right to determine any questions that arise
in connection with the grant or exercise of the Option Right. 
  
 16. Successors and Assigns. Without limiting Section 7 hereof, the provisions of this Agreement shall inure to the benefit of, and be binding upon, the successors, administrators, heirs, legal representatives and assigns of the
Optionee, and the successors and assigns of the Company. 
  
 17. Governing Law. The interpretation, performance, and enforcement of this Agreement shall be governed by the laws of the State of Ohio, without giving effect to the principles of conflict of laws thereof. 
  
 18. Notices. Any notice to the Company provided for herein shall be in
writing to the Company (Attention: Secretary) and any notice to the Optionee shall be addressed to the Optionee at his or her address on file with the Company. Except as otherwise provided herein, any written notice shall be deemed to be duly given
if and when delivered personally or deposited in the United States mail, first class certified or registered mail, postage and fees prepaid, return receipt requested, and addressed as aforesaid. Any party may change the address to which notices are
to be given hereunder by written notice to the other party as herein specified (provided that for this purpose any mailed notice shall be deemed given on the third business day following deposit of the same in the United States mail). 
  
 19. Compliance with Section 409A of the Code. To the extent
applicable, it is intended that this Agreement and the Plan comply with the provisions of Section 409A of the Code. This Agreement and the Plan shall be administered in a manner consistent with this intent, and any provision that would cause the
Agreement or the Plan to fail to satisfy Section 409A of the Code shall have no force and effect until amended to comply with Section 409A of the Code (which amendment may be retroactive to the extent permitted by Section 409A of the Code and,
notwithstanding Section 13 hereof, may be made by the Company without the consent of the Optionee). 
  

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 IN WITNESS WHEREOF, the Company has caused this Agreement to be executed on its behalf by its duly
authorized officer and the Optionee has also executed this Agreement in duplicate, as of the day and year first above written. 
  

			
	NATIONAL INTERSTATE CORPORATION
		
	By:	 	  

	Name:	 	 
	Title:	 	 

  
 The undersigned
hereby acknowledges receipt of an executed original of this Agreement and a copy of the Plan, and accepts the award of the Option Right granted thereunder on the terms and conditions set forth herein and in the Plan. 
  

			
	

	Optionee
		
	Date:	 	  

  

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