Document:

Exhibit
10.11

 

[Informal
English Translation]

 

Tenancy Agreement

 

Made and
executed in Jerusalem this 29th day of September 2014

 

Between:

 

Ms. Rachel Zacks

Identity
No. 29581

 

Dr. Moshe
Eliash Advocate

Identity
No. 1940998

(jointly
and severally)

(hereinafter
– “the Landlord”)

of the one
part;

 

And:

 

Sol-Gel
Technologies Ltd.

Corporate
number 51-254469-3

(hereinafter called: “the Tenant”)

 

of the other part

 

		WHEREAS	by a tenancy agreement
                                         signed between the parties on October 10, 2007, (hereinafter called: “the
                                         Tenancy Agreement”) the Tenant took a tenancy of the Premises as defined in
                                         the Agreement; and

 

		WHEREAS	the Tenant wishes to take and the Landlord wishes to grant a tenancy of an additional area in the
Building as defined in the Tenancy Agreement

 

It is therefore declared and
agreed between the parties as follows:

 

		1.	The preamble to this Agreement constitutes an integral
part thereof.

 

		2.	The Landlord hereby grants to the Tenant a tenancy of an area of approximately 118.4 square meters
(net) being 148 square meters (gross) on the top storey of the Building, as described in the plan annexed hereto and constituting
an integral part of this Agreement.

 

		3.	That area mentioned will be called “the Premises”.

 

		4.	The tenancy term shall commence on October
                                         1, 2014 and expire at the end of the Tenancy Term according to the Tenancy Agreement.

 

    	 	1	 

     

    

 

		5.	The monthly rent for the Premises is
                                         set at NIS 65 per square meter (gross) at the sum of NIS 9620, such sum being linked
                                         to the Consumer Price Index published on August 15, 2014 (102.4 points).

 

		6.	The rent will be paid for three months in advance every calendar quarter as defined in the Tenancy
Agreement. Payment for the first three months of the tenancy will be made on the execution of this agreement.

 

		7.	The management fees for the Premises shall be at the rate of NIS 13 per square meter (gross), and
will be paid according to the provisions of the Tenancy Agreement. The Tenant will sign with the Management Company a management
agreement pursuant to the provisions of the Tenancy Agreement, immediately after the signature of this Agreement.

 

		8.	The Tenant will pay on the execution of this Agreement, a surety at the rate of four months of
the tenancy together with VAT pursuant to the provisions of clause 33 of the Tenancy Agreement.

 

		9.	For the avoidance of any doubt it is hereby clarified that to the extent the Tenant will terminate
the Tenancy Term according to the Tenancy Agreement according to the provisions of clause 7(b)(2) of the Tenancy Agreement, the
tenancy term according to this Agreement will likewise come to an end on the same date.

 

		10.	Subject as herein provided, all the terms of the Tenancy Agreement will mutatis mutandis
apply to the tenancy according to this Agreement.

 

In witness whereof the parties have set their hands on the date
first above written

 

	/s/ Dr. Moshe Eliash	 	/s/ Kobbi Nir /s/ Ido Zalel
	The Landlord	 	Sol-Gel Technologies Ltd.
	in his own name	 	The Tenant
	and in the name of Ms. Rachel Zacks	 	 
	by general power of attorney	 	 

 

    	 	2Exhibit
10.12

 

[Informal
English Translation]

 

Second Addendum
to the Tenancy Agreement of 10.10.2007

 

Made and
executed in Jerusalem this 30th day of March 2016

 

Between:

 

Ms. Rachel
Zacks Identity No. 29581

Dr. Moshe
Eliash Identity No. 1940998

(jointly
and severally)

(hereinafter
called – “the Landlord”)

 

of the one
part;

 

And:

 

Sol-Gel
Technologies Ltd.

Corporate
number 51-2544693

(hereinafter called: “the Tenant”)

 

of the other part

 

		WHEREAS	by a tenancy agreement
                                         signed between the parties on 10th October, 2007, (hereinafter called: “the
                                         Tenancy Agreement”) the Tenant took a tenancy of an area constituting the entire
                                         fifth floor in the building situated at Parcel 18 of Block 3850 in Ness Ziona (“the
                                         Building”) as well as 43 covered parking places in the underground car park
                                         of the building (the area and the parking places being together called: “the
                                         Original Premises”); and

 

		WHEREAS	On 29th September, 2014, the first addendum was signed between the parties to the Tenancy Agreement
whereby the Tenant took a tenancy of an additional area of 148 square meters (gross) on the top floor (sixth floor) in the Building
as marked in blue on the plan attached hereto as Appendix “A” (“the Additional Area”).

 

			The Original Premises together with the Additional Area will be in this Addendum called: “the
Existing Premises”; and

 

		WHEREAS	The Tenant wishes to take and the Landlord wishes to grant to the Tenant, a tenancy of additional
areas in the Building constituting the New Additional Areas (as hereinafter defined); and

 

		WHEREAS	The parties wish to extend the Tenancy Term of the Presently Existing Premises (as hereinafter
defined).
	 	 	 
	 	 	It is therefore
declared and agreed between the parties as follows:

 

		1.	The preamble to this Agreement constitutes an integral
part thereof.

 

    	 	1	 

     

    

 

		2.	The Landlord hereby grants to the Tenant a tenancy of the
area on the top floor of the Building of 174 square meters (gross) west of the Additional Area and a further area on the top floor
of the Building of 185 square meters (gross) east of the Additional Area, as marked in yellow on the plan annexed hereto as Appendix
“A” and which constitutes an integral part of this Agreement (the Additional Areas to the west and east mentioned
will be hereinafter called: “the New Additional Areas”).

 

		3.	The New Additional Areas together with the Existing Premises
will be called in this Addendum “the Presently Existing Premises”.

 

		4.	The Tenancy Term in respect of the New Additional Areas will commence on  March 1, 2017 (“the Operative
                                                         Date”) and expire at the end of the Adjusted Tenancy Term (as hereinafter defined).

 

		5.	The Tenancy Term in respect of the Presently Existing Premises is hereby extended and will expire
on December 31, 2020 (“the Adjusted Tenancy Term”).

 

		6.	The monthly rent in respect of the Premises will, as from the Operative Date until the expiration
of the Adjusted Tenancy Term, stand at NIS 121,972.75 plus VAT (“the Rent”) according to the following breakdown:

 

		5.1	The monthly rent in respect of the area of 1090.71
square meters (gross) on the fifth floor and 507 square meters (gross) on the top floor will stand at NIS 65 per square meters,
and in the aggregate NIS 103,851.15.

 

		5.2	The monthly rent in respect of the internal bomb shelter
having an area of 30.72 square meters will stand at NIS 30 per square meters, and in the aggregate NIS 921.6.

 

		5.3	The monthly rent in respect of the parking places
will stand at the sum of NIS 400 per parking place, and in the aggregate in respect of 43 parking places, at the sum of NIS 17,200.0.

 

The rent is linked
to the Consumer Price Index that was published on August 15, 2014 (102.4 points).

 

		7.	The rent will be paid for three months in advance every calendar quarter as defined in the Tenancy
Agreement. Payment of the rent in respect of the New Additional Areas for the first three months of the tenancy in the sum of NIS
70,005 (plus VAT) will be made on the date of the execution of this Agreement.

 

		8.	The monthly management fees for the Presently Exisiting Premises will be at the rate of NIS 13
per square meter (gross) and in the aggregate NIS 20,770.23, and be paid according to the provisions of the Tenancy Agreement.
The Tenant will sign with the Management Company an appropriate amendment to the management agreement to the extent this will be
required pursuant to the provisions of this Addendum, immediately after the execution of this Agreement.

 

		9.	The Tenant will pay on the execution of this Agreement, a surety of four months of the tenancy
plus VAT in respect of the New Additional Areas pursuant to the provisions of clause 33 of the Tenancy Agreement.

 

		10.	Subject as herein provided, all the terms of the Tenancy Agreement will mutatis mutandis
apply to the tenancy according to this Agreement.

 

    	 	2	 

     

    

 

In witness whereof the parties have set their
hands on the date first above written

  

	/s/ Dr. Moshe Eliash	 	/s/ Kobbi Nir /s/ Alon Seri-Levy
	The Landlord	 	Sol-Gel Technologies Ltd.
	in his own name	 	The Tenant
	and in the name of Ms. Rachel Zacks	 	 
	by general power of attorney	 	 

 

    	 	3Exhibit
10.13

 

[Informal
English Translation]

 

Memorandum
of Agreement 

 

Made and
executed in Jerusalem this 20th day of September 2016

 

Between:

 

Ms. Rachel Zacks Identity
No. 29581

Dr. Moshe Eliash Identity
No. 1940998

(each of them severally and jointly)

(hereinafter called – “the
Landlord”)

 

of the one
part;

 

And:

 

Sol-Gel Technologies Ltd.

Corporate number 51-2544693

(hereinafter called: “the Tenant”)

 

of the other part

 

		WHEREAS:	A Second Addendum to the Tenancy Agreement of  October 10, 2007 was signed between the parties
                                                                         on  March 30, 2016; and

 

		WHEREAS:	The parties wish to modify the particulars of the New Additional Areas (as defined in the Addendum)
and in consequence the details of the payments described in the Addendum fall to be modified.
	 	 	 
	 	 	It is therefore
declared and agreed between the parties as follows:

 

		1.	The preamble to this Memorandum of Agreement constitutes
an integral part thereof.

 

		2.	The area that is leased to the Tenant in addition to the
“Additional Area” as defined in the Addendum is an area of 373 square meters as marked in the attached plan being
Appendix “A”, and this will replace the “New Additional Areas” as defined in the Addendum.

 

		3.	The rent described in clause 6 of the Addendum for the area of 1090.71 square meters (gross) on
the first floor and 521 square meters (gross) on the top floor will stand at NIS 65 per square meter, and in the aggregate NIS
104,761.15.

 

		4.	The rent described in clause 7 of the Addendum will stand at NIS 72,735.00 for three months and the Tenant will pay the sum
of NIS 2,728.00 the difference of the rent in excess of the sum of NIS 70,007.00 which was paid according to the provisions of
the Amendment, (plus VAT), on the execution of this Memorandum of Agreement.

 

    	 	1	 

     

    

 

		5.	The amount of the management fees owed by the Tenant pursuant to clause 8 of the Addendum will
stand at NIS 20,952.23 per month.

 

		6.	The amount of the collateral according to clause 9 of the
Addendum will stand at NIS 96,980.00 instead of the sum of NIS 93,340.00 that was paid according to the provisions of the Addendum,
and the Tenant will pay the difference in the sum of NIS 3,640 (plus VAT) on the execution of this Memorandum of Agreement.

 

		7.	Subject as herein provided, all of the provisions of the Addendum shall remain in full force and
effect.

 

In witness whereof the parties have set their
hands on the date first above written

 

	/s/ Dr. Moshe Eliash	 	/s/ Kobbi Nir
	The Landlord	 	Sol-Gel Technologies Ltd.
	in his own name	 	 
	and in the name of Ms. Rachel Zacks	 	 
	by general power of attorney	 	 

 

    	 	2

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