Document:

EX-10.11

 Exhibit 10.11 

ESCROW DEPOSIT AGREEMENT 
 This ESCROW
DEPOSIT AGREEMENT (this “Agreement”) dated as of this [    ] day of [            ] 2017, by and among GENPREX, INC., a Delaware corporation
(the “Company”), having an address at 100 Congress Avenue, Suite 2000, Austin, Texas 78701, NETWORK 1 FINANCIAL SECURITIES, INC., a New Jersey corporation (the “Underwriter”), having an address at The
Galleria, Penthouse, 2 Bridge Avenue, Building 2, Red Bank, NJ 07701, and SIGNATURE BANK (the “Escrow Agent”), a New York State chartered bank, having an office at 565 Fifth Avenue, 12th Floor, New York, New York 10017. All capitalized terms not herein defined shall have the meaning ascribed to them in that certain Preliminary Prospectus, dated September 8, 2017, of the Company,
including all attachments, schedules and exhibits thereto (the “Prospectus”) included in Registration Statement on Form S-1 (File No. 333-219386).

 W I T N E S S E T H: 

WHEREAS, pursuant to the terms of the Prospectus the Company desires to sell (the “Offering”) a minimum of $12,500,000
(the “Minimum Amount”) and a maximum of $22,500,000 (the “Maximum Amount”) of its shares (the “Shares”). Each Share is being sold at a price range between a minimum price of $4.00 per Share and a
maximum price of $6.00 per Share; and 
 WHEREAS, unless the Minimum Amount is sold by the date that is sixty (60) days after the
date of the final prospectus (the “Termination Date”), the Offering shall terminate and all funds shall be returned to the subscribers in the Offering, and if the Minimum Amount is met, the Offering may continue until the
Termination Date; and 
 WHEREAS, the Company and Underwriter desire to establish an escrow account with the Escrow Agent into which
the Company and Underwriter shall instruct Investors introduced to the Company by Underwriter (the “Investors”) to deposit checks and other instruments for the payment of money made payable to the order of “Signature Bank as
Escrow Agent for Genprex, Inc.,” and Escrow Agent is willing to accept said checks and other instruments for the payment of money in accordance with the terms hereinafter set forth; and 

WHEREAS, the Company, as issuer, and Underwriter, as an introducing broker-dealer, represent and warrant to the Escrow Agent that they
will comply with all of their respective obligations under applicable state and federal securities laws and regulations with respect to the Offering; and 

WHEREAS, the Company and Underwriter represent and warrant to the Escrow Agent that they have not stated to any individual or entity
that the Escrow Agent’s duties will include anything other than those duties stated in this Agreement; and 
 WHEREAS, the
Company and Underwriter warrant to the Escrow Agent that a copy of each document that has been delivered to Investors and third parties that include Escrow Agent’s name and duties, has been attached hereto as Schedule I. 

  
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 NOW, THEREFORE, IT IS AGREED as follows: 

1.    Delivery of Escrow Funds. 

(a)     Underwriter and the Company shall instruct Investors to deliver to Escrow Agent checks made payable to the order of
“Signature Bank, as Escrow Agent for Genprex, Inc.” or wire transfer to Signature Bank, 565 Fifth Avenue, 12th Floor, New York, New York 10017, ABA No. 026013576 for credit to
Signature Bank, as Escrow Agent for Genprex, Inc., Account No.                     , in each case, with the name and address of the individual or
entity making payment. In the event any Investor’s address is not provided to Escrow Agent by the Investor, then Underwriter and/or the Company agree to promptly provide Escrow Agent with such information in writing. The checks or wire
transfers shall be deposited into a non-interest-bearing account at Signature Bank entitled “Genprex, Inc., Signature Bank, as Escrow Agent” (the “Escrow Account”). 

(b)    The collected funds deposited into the Escrow Account are referred to as the “Escrow Funds.” 

(c)    The Escrow Agent shall have no duty or responsibility to enforce the collection or demand payment of any funds
deposited into the Escrow Account. If, for any reason, any check deposited into the Escrow Account shall be returned unpaid to the Escrow Agent, the sole duty of the Escrow Agent shall be to return the check to the Investor and advise the Company
and Underwriter promptly thereof. 
 2.    Release of Escrow Funds. The Escrow Funds shall be paid by the Escrow Agent in
accordance with the following: 
 (a)    In the event that the Company and Underwriter advise the Escrow Agent in writing
that the Offering has been terminated (the “Termination Notice”), the Escrow Agent shall promptly return the funds paid by each Investor to said Investor without interest or offset. 

(b)     Provided that the Escrow Agent does not receive the Termination Notice in accordance with Section 2(a) and
the Minimum Amount is deposited into the Escrow Account on or prior to the Termination Date, the Escrow Agent shall, upon receipt of written instructions, in the form of Exhibit A, attached hereto and made a part hereof, or in a form
and substance satisfactory to the Escrow Agent, received from the Company and Underwriter, pay the Escrow Funds in accordance with such written instructions, such payment or payments to be made by wire transfer within one (1) business day of
receipt of such written instructions. Such instructions must be received by the Escrow Agent no later than 3:00 PM Eastern Time on a Banking Day for the Escrow Agent to process such instructions that Banking Day. 

(c)    If by 3:00 P.M. Eastern time on the Termination Date, the Escrow Agent has not received written instructions from
the Company and Underwriter regarding the disbursement of the Escrow Funds or the total amount of the Escrow Funds is less than the Minimum Amount, then the Escrow Agent shall promptly return the Escrow Funds to the Investors without interest or
offset. The Escrow Funds returned to each Investor shall be free and clear of any and all claims of the Escrow Agent. 

  
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 (e)    The Escrow Agent shall not be required to pay any uncollected funds or
any funds that are not available for withdrawal. 
 (f)    If the Termination Date, Final Termination Date or any date
that is a deadline under this Agreement for giving the Escrow Agent notice or instructions or for the Escrow Agent to take action is not a Banking Day, then such date shall be the Banking Day that immediately precedes that date. A “Banking
Day” is any day other than a Saturday, Sunday or a day that a New York State chartered bank is not legally obligated to be opened. 

3.    Acceptance by Escrow Agent. The Escrow Agent hereby accepts and agrees to perform its obligations hereunder, provided that:

 (a)    The Escrow Agent may act in reliance upon any signature believed by it to be genuine, and may assume that any
person who has been designated by Underwriter or the Company to give any written instructions, notice or receipt, or make any statements in connection with the provisions hereof has been duly authorized to do so. Escrow Agent shall have no duty to
make inquiry as to the genuineness, accuracy or validity of any statements or instructions or any signatures on statements or instructions. The names and true signatures of each individual authorized to act singly on behalf of the Company and
Underwriter are stated in Schedule II, which is attached hereto and made a part hereof. The Company and Underwriter may each remove or add one or more of its authorized signers stated on Schedule II by notifying the Escrow Agent of
such change in accordance with this Agreement, which notice shall include the true signature for any new authorized signatories. 

(b)    The Escrow Agent may act relative hereto in reliance upon advice of counsel in reference to any matter connected
herewith. The Escrow Agent shall not be liable for any mistake of fact or error of judgment or law, or for any acts or omissions of any kind, unless caused by its willful misconduct or gross negligence. 

(c)    Underwriter and the Company agree to indemnify and hold the Escrow Agent harmless from and against any and all
claims, losses, costs, liabilities, damages, suits, demands, judgments or expenses (including but not limited to reasonable attorney’s fees) claimed against or incurred by Escrow Agent arising out of or related, directly or indirectly, to this
Escrow Agreement except to the extent caused by the Escrow Agent’s gross negligence or willful misconduct. 

(d)    In the event that the Escrow Agent shall be uncertain as to its duties or rights hereunder, the Escrow Agent shall
be entitled to (i) refrain from taking any action other than to keep safely the Escrow Funds until it shall be directed otherwise by a court of competent jurisdiction, or (ii) deliver the Escrow Funds to a court of competent jurisdiction.

 (e)    The Escrow Agent shall have no duty, responsibility or obligation to interpret or enforce the terms of any
agreement other than Escrow Agent’s obligations hereunder, and the Escrow Agent shall not be required to make a request that any monies be delivered to the Escrow Account, it being agreed that the sole duties and responsibilities of the Escrow
Agent shall be to the extent not prohibited by applicable law (i) to accept checks or other instruments for the payment of money and wire transfers delivered to the Escrow Agent for the Escrow Account and deposit said checks and wire transfers
into the non-interest bearing Escrow Account, and (ii) to disburse or refrain from disbursing the Escrow Funds as stated above, provided that the checks received by the Escrow Agent have been collected
and are available for withdrawal. 

  
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 4.    Escrow Account Statements and Information. The Escrow Agent agrees to
send to the Company and/or the Underwriter a copy of the Escrow Account periodic statement, upon request in accordance with the Escrow Agent’s regular practices for providing account statements to its
non-escrow clients and to also provide the Company and/or Underwriter, or their designee, upon request other deposit account information, including Escrow Account balances, by telephone or by computer
communication, to the extent practicable. The Company and Underwriter agree to complete and sign all forms or agreements required by the Escrow Agent for that purpose. The Company and Underwriter each consent to the Escrow Agent’s release of
such Escrow Account information to any of the individuals designated by Company or Underwriter, which designation has been signed in accordance with Section 3(a) by any of the persons in Schedule II. Further, the Company and
Underwriter have an option to receive e-mail notification of incoming and outgoing wire transfers. If this e-mail notification service is requested and subsequently
approved by the Escrow Agent, each of the Company and Underwriter agrees to provide a valid e-mail address and other information necessary to set-up this service and
sign all forms and agreements required for such service. The Company and Underwriter each consents to the Escrow Agent’s release of wire transfer information to the designated e-mail address(es). The
Escrow Agent’s liability for failure to comply with this section shall not exceed the cost of providing such information. 

5.    Resignation and Termination of the Escrow Agent. The Escrow Agent may resign at any time by giving 30 days’ prior
written notice of such resignation to Underwriter and the Company. Upon providing such notice, the Escrow Agent shall have no further obligation hereunder except to hold as depository the Escrow Funds that it receives until the end of such 30-day period. In such event, the Escrow Agent shall not take any action, other than receiving and depositing Investors checks and wire transfers in accordance with this Agreement, until the Company has designated a
banking corporation, trust company, attorney or other person as successor. Upon receipt of such written designation signed by Underwriter and the Company, the Escrow Agent shall promptly deliver the Escrow Funds to such successor and shall
thereafter have no further obligations hereunder. If such instructions are not received within 30 days following the effective date of such resignation, then the Escrow Agent may deposit the Escrow Funds held by it pursuant to this Agreement with a
clerk of a court of competent jurisdiction pending the appointment of a successor. In either case provided for in this Section, the Escrow Agent shall be relieved of all further obligations and released from all liability thereafter arising with
respect to the Escrow Funds. 
 6.    Termination. The Company and Underwriter may terminate the appointment of the Escrow Agent
hereunder upon written notice specifying the date upon which such termination shall take effect, which date shall be at least 30 days from the date of such notice. In the event of such termination, the Company and Underwriter shall, within 30 days
of such notice, appoint a successor escrow agent and the Escrow Agent shall, upon receipt of written instructions signed by the Company and Underwriter, turn over to such successor escrow agent all of the Escrow Funds; provided,
however, that if the Company and Underwriter fail to appoint a successor escrow agent within such 30-day period, such termination notice shall be null and void and the Escrow Agent shall continue to be
bound by all of the provisions hereof. Upon receipt of the 

  
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Escrow Funds, the successor escrow agent shall become the escrow agent hereunder and shall be bound by all of the provisions hereof and Escrow Agent shall be relieved of all further obligations
and released from all liability thereafter arising with respect to the Escrow Funds and under this Agreement. 

7.    Investment. All funds received by the Escrow Agent shall be held only in non-interest
bearing bank accounts at Signature Bank. 
 8.    Compensation. Escrow Agent shall be entitled, for the duties to be performed by
it hereunder, to a fee of $4,000.00, which fee shall be paid by the Company upon the signing of this Agreement. In addition, the Company shall be obligated to reimburse Escrow Agent for all fees, costs and expenses incurred or that become due in
connection with this Agreement or the Escrow Account, including reasonable attorney’s fees. Neither the modification, cancellation, termination or rescission of this Agreement nor the resignation or termination of the Escrow Agent shall affect
the right of Escrow Agent to retain the amount of any fee which has been paid, or to be reimbursed or paid any amount which has been incurred or becomes due, prior to the effective date of any such modification, cancellation, termination,
resignation or rescission. To the extent the Escrow Agent has incurred any such expenses, or any such fee becomes due, prior to the closing of the Offering, the Escrow Agent shall advise the Company and the Company shall direct all such amounts to
be paid directly at any such closing. The Escrow Agent shall be entitled to a fee of $1,000.00 in the event this Agreement is amended for any reason in accordance with Section 10(d). 

9.    Notices. All notices, requests, demands and other communications required or permitted to be given hereunder shall be in
writing and shall be deemed to have been duly given if sent by hand-delivery, by facsimile (followed by first-class mail), by nationally recognized overnight courier service or by prepaid registered or certified mail, return receipt requested, to
the addresses set forth below: 
 If to the Underwriter: 

Network 1 Financial Securities, Inc. 

Galleria, Penthouse 
 2 Bridge
Avenue, Building 2 
 Red Bank, NJ 07701 

Attn: Damon D. Testaverde, Director of Investment Banking 

Fax No.: (732) 758-6671 

With a copy (which shall not constitute notice) to: 

Magri Law, LLC 
 2642 NE 9th Ave. 
 Fort Lauderdale, FL 33334 

Attn: Philip Magri 
 Email:
pmagri@magrilaw.com 
 Fax No.: 646-836-9200 

  
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 If to the Company: 

Genprex, Inc. 
 100 Congress
Avenue, Suite 2000 
 Austin, Texas 78701 

Attn: J. Rodney Varner 
 Chief
Executive Officer 
 With a copy (which shall not constitute notice) to: 

Streusand Landon & Ozburn, LLP 

811 Barton Springs Road, Suite 811 

Austin, TX 78704 
 Attn:
Christopher J. Ozburn 
 Fax: (512) 236-9904 

If to Escrow Agent: 

Signature Bank 
 565 Fifth Avenue,
12th Floor 
 New York, New York 10017 

Attention: Ed Sirlin, Group Director & Senior Vice President 

With a copy (which shall not constitute notice) to: 

Signature Bank 
 565 Fifth Avenue,
8th Floor 
 New York, New York 10017 

Attention: General Counsel 

Fax: (646) 758-8188 

10.    General. 

(a)    This Agreement shall be governed by and construed and enforced in accordance with the laws of the State of New York
applicable to agreements made and to be entirely performed within such State, without regard to choice of law principles and any action brought hereunder shall be brought in the courts of the State of New York, located in the County of New York.
Each party hereto irrevocably waives any objection on the grounds of venue, forum nonconveniens or any similar grounds and irrevocably consents to service of process by mail or in any manner permitted by applicable law and consents to the
jurisdiction of said courts. EACH OF THE PARTIES HERETO HEREBY WAIVES ALL RIGHT TO TRIAL BY JURY IN ANY ACTION, PROCEEDING OR COUNTERCLAIM ARISING OUT OF THE TRANSACTIONS CONTEMPLATED BY THIS AGREEMENT. 

(b)    This Agreement sets forth the entire agreement and understanding of the parties with respect to the matters
contained herein and supersedes all prior agreements, arrangements and understandings relating thereto. 

  
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 (c)    All of the terms and conditions of this Agreement shall be binding
upon, and inure to the benefit of and be enforceable by, the parties hereto, as well as their respective successors and assigns. 

(d)    This Agreement may be amended, modified, superseded or canceled, and any of the terms or conditions hereof may be
waived, only by a written instrument executed by each party hereto or, in the case of a waiver, by the party waiving compliance. The failure of any party at any time or times to require performance of any provision hereof shall in no manner affect
its right at a later time to enforce the same. No waiver of any party of any condition, or of the breach of any term contained in this Agreement, whether by conduct or otherwise, in any one or more instances shall be deemed to be or construed as a
further or continuing waiver of any such condition or breach or a waiver of any other condition or of the breach of any other term of this Agreement. No party may assign any rights, duties or obligations hereunder unless all other parties have given
their prior written consent to such assignment. 
 (e)    If any provision included in this Agreement proves to be
invalid or unenforceable, it shall not affect the validity of the remaining provisions. 
 (f)    This Agreement and any
modification or amendment of this Agreement may be executed in several counterparts or by separate instruments and all of such counterparts and instruments shall constitute one agreement, binding on all of the parties hereto. 

11.    Form of Signature. The parties hereto agree to accept a facsimile transmission copy of their respective actual signatures as
evidence of their actual signatures to this Agreement and any modification or amendment of this Agreement; provided, however, that each party who produces a facsimile signature agrees, by the express terms hereof, to place, promptly
after transmission of his or her signature by fax, a true and correct original copy of his or her signature in overnight mail to the address of the other party. 

12.     No Third-Party Beneficiaries. This Agreement is solely for the benefit of the parties and their respective successors
and permitted assigns, and no other person has any right, benefit, priority, or interest under or because of the existence of this Agreement. 

  
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 IN WITNESS WHEREOF, the parties have duly executed this Agreement as of the date first set forth above.

  

									
	GENPREX, INC.	 		 	NETWORK 1 FINANCIAL SECURITIES, INC.
					
	By:	 	  
	 		 	By:	 	  

	Name:	 	J. Rodney Varner	 		 	Name:	 	Damon D. Testaverde
	Title:	 	Chief Executive Officer	 		 	Title:	 	Director of Investment Banking

  

			
	SIGNATURE BANK

			
		
	By:	 	  

	Name:	 	
	Title:	 	
		
	By:	 	  

	Name:	 	
	Title:	 	

  
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 Schedule I 

OFFERING DOCUMENTS 
  

			
	Escrow Deposit Agreement – Public Offering	  	

  
 9 

 Schedule II 

The Escrow Agent is authorized to accept instructions signed or believed by the Escrow Agent to be signed by any one of the following on
behalf of the Company and Underwriter. 
 Genprex, Inc. 
  

			
	 Name
	 	 True Signature

	 J. Rodney Varner
	 	  

 Network 1 Financial Securities, Inc. 

 

			
	 Name
	 	 True Signature

	 Damon D. Testaverde
	 	  

	
                   
                         
	 	  

  

			
	Escrow Deposit Agreement – Public Offering	  	

  
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 Exhibit A 

FORM OF ESCROW RELEASE NOTICE 

Date: 
 Signature Bank 

565 Fifth Avenue, 12th Floor 

New York, New York 10016 
 Attention: Ed Sirlin, Group
Director & SVP  
 Dear Mr. Sirlin: 

In accordance with the terms of Section 2(b) of that Escrow Deposit Agreement dated as of
            , 2017 (the “Escrow Agreement”), by and between Genprex, Inc. (the “Company”), Signature Bank (the “Escrow Agent”) and Network 1 Financial
Securities, Inc. (“Underwriter”), the Company and Underwriter hereby notify the Escrow Agent that the                      closing will be
held on                      for gross proceeds of $            . 

PLEASE DISTRIBUTE FUNDS BY WIRE TRANSFER AS FOLLOWS (wire instructions attached): 
  

					
	  
	 	:            	  	$                
			
	  
	 	:            	  	$
			
	  
	 	:            	  	$

 Very truly yours, 
 GENPREX,
INC. 
  

			
	By:	 	  

	Name:	 	J. Rodney Varner
	Title:	 	Chief Executive Officer

 NETWORK 1 FINANCIAL SECURITIES, INC. 
  

			
	By:	 	  

	Name:	 	Damon D. Testaverde
	Title:	 	Director of Investment BankingEX-10.17

 Exhibit 10.17 

EXECUTIVE EMPLOYMENT AGREEMENT 

This Executive Employment Agreement (the “Agreement”) is entered into between Genprex, Inc.
(“Company”) and Rodney Varner (“Employee”). This Agreement is effective as of the effective date provided below (“Effective Date”) 

In consideration of the promises and the terms and conditions set forth in this Agreement, the parties agree as follows: 

1. Position and Duties. As of the Effective Date, Employee will serve as Chairman of the Board, President and Chief
Executive Officer of the Company and will report to the Company’s Board of Directors. Employee will render such business and professional services in the performance of his duties, consistent with Employee’s position, as shall reasonably
be assigned to him by the Company. 
 2. Election to the Board. Employee will continue to serve on the Company’s
Board of Directors (the “Board”) following the Effective Date. Employee may be removed from the Board in accordance with applicable law and the Company’s bylaws. 

3. Exclusive Service. Employee will be expected to devote his full working time and attention to the business of
the Company, and, except as provided herein, will not render services to any other business without the prior approval of the Board or, directly or indirectly, engage or participate in any business that is competitive in any manner with the business
of the Company. Employee will also be expected to comply with and be bound by the Company’s operating policies, procedures and practices that are from time to time in effect during the term of his employment. Employee is a lawyer who is winding
down his private law practice. Employee is permitted to perform legal services for those who were clients before the effective date of this Agreement; however, it is expected that such services will not consume more than ten (10) hours per
month on average of Employee’s time. Employee is also permitted to manage investments on behalf of himself and his family owned entities. 

4. At-Will Employment. Employee and the Company understand
and acknowledge that Employee’s employment with the Company constitutes “at-will” employment, and the employment relationship may be terminated at any time, with or without cause and with or
without notice. 
 5. Compensation and Benefits. 

5.1 Base Salary. While employed by the Company pursuant to this Agreement, the Company shall pay the Employee an
annual base salary of $476,861 (the “Base Salary”), payable in accordance with the Company’s normal payroll practices. The Company shall periodically review (at least annually) Employee’s compensation and benefits,
provided that any changes thereto shall be determined by the Company in its sole and absolute discretion. 
 5.2 Management by
Objectives Bonus. Employee will also be eligible to receive an annual cash bonus of $357,646 (the “Target Bonus”), upon the achievement of performance objectives mutually agreed upon between Employee and the
Board within Ninety (90) days following the Effective Date. To receive payment of any bonus Employee must be employed by the Company at the time bonuses are paid. Thereafter, Employee will be eligible to receive an annual bonus in such amount
and upon such terms as shall be determined by the Board. 

  
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 5.3 Employee Benefits. Employee shall be eligible to participate in
all employee benefit plans and arrangements, including, but not limited to, medical, dental, vision and long-term disability insurance benefits and arrangements, as are made available by the Company to its other senior executives, subject to the
terms and conditions thereof. 
 5.4 Vacation. Employee will be entitled to paid vacation and holidays pursuant
to the terms of the Company’s vacation policy as may exist from time to time. 
 6. Equity Grants. The
Company may from time to time grant Employee options or other forms of equity under the Company’s 2017 Equity Incentive Plan (“Plan”) upon such terms and conditions as may be determined by the Board in its sole discretion. 

7. Expenses. The Company will, in accordance with applicable Company policies and guidelines, reimburse Employee
for all reasonable and necessary expenses incurred by Employee in connection with his performance of services on behalf of the Company. Without limiting the foregoing, expenses will be deemed reasonable if they are permitted by the Company’s
written policies. 
 8. Inventions and Proprietary Information, Non-Solicitation. 

8.1 Proprietary Information and Inventions Agreement. Employee hereby agrees to execute the Company Confidential
Information, Assignment of Inventions, and Noncompetition Agreement attached hereto as Exhibit A. 
 9. Definitions.

 9.1 Cause. For purposes of this Agreement, “Cause” means (i) a determination
by the Board that Employee’s performance is unsatisfactory after there has been delivered to Employee a written demand for performance which describes the specific deficiencies in Employee’s performance and the specific manner in which
Employee’s performance must be improved, and which provides thirty (30) business days from the date of notice to remedy such performance deficiencies; (ii) Employee’s conviction of or plea of nolo contendere to a felony or a
crime involving moral turpitude which the Board reasonably finds has had or will have a detrimental effect on the Company’s reputation or business, (iii) Employee engaging in an act of gross negligence or willful misconduct in the
performance of his employment obligations and duties that materially harms the Company, (iv) Employee’s committing an act of fraud against, material misconduct or willful misappropriation of property belonging to the Company;
(v) Employee’s material breach of the Company Confidential Information, Assignment of Inventions, and Noncompetition Agreement or other unauthorized misuse of the Company’s trade secrets or proprietary information. 

9.2 Change in Control. For purposes of this Agreement, “Change in Control” means (i) a
sale, conveyance, exchange or transfer in which any person or entity, other than persons or entities who as of immediately prior to such sale, conveyance, exchange or transfer own securities in the Company, either directly or indirectly, becomes the
beneficial owner, directly or indirectly, of securities of the Company representing fifty (50%) percent of the total voting power of all its then outstanding voting securities; (ii) a merger or consolidation of the Company in which its voting
securities immediately prior to the merger or consolidation do not represent, or are not converted into securities that represent, a majority of the voting power of all voting securities of the surviving entity immediately after the merger or
consolidation; or (iii) a sale of substantially all of the assets of the Company or a liquidation or dissolution of the Company. 

9.3 Disability. For purposes of this Agreement, “Disability” shall have that meaning set forth in
Section 22(e)(3) of the Internal Revenue Code of 1986, as amended. 

  
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 9.4 Good Reason. For purposes of this Agreement, “Good
Reason” means any of the following taken without the Employee’s written consent and provided (a) the Company receives, within ninety (90) days following the occurrence of any of the events set forth in clauses
(i) through (iv) below, written notice from the Employee specifying the specific basis for Employee’s belief that Employee is entitled to terminate employment for Good Reason, (b) the Company fails to cure the event constituting Good
Reason within thirty (30) days after receipt of such written notice thereof, and (c) the Employee terminates employment within thirty (30) days following expiration of such cure period: (i) a material change in Employee’s
position, titles, offices or duties; (ii) an assignment of any significant duties to Employee that are inconsistent with Employee’s positions or offices held under this Agreement; (iii) a decrease in Employee’s then current
annual base salary by more than 10% (other than in connection with a general decrease in the salary of all other similarly situated employees of the Company); or (iv) the relocation of the Employee to a facility or a location more than fifty
(50) miles from Employee’s then current location. 
 10. Effect of Separation from Service. For purposes of
this Agreement, no payment will be made to Employee upon termination of Employee’s employment unless such termination constitutes a “separation from service” within the meaning of Section 409A of the Code, and Section 1.409A-1(h) of the regulations promulgated thereunder. 
 10.1 Separation for
Cause, Death, Disability or Voluntary Separation from Service. In the event of any separation from service of Employee’s employment by the Company for Cause or in the event of the Employee’s death, Disability or voluntary
separation from service at any time and for any reason, the Employee will be paid only (i) any earned but unpaid Base Salary, and (ii) other unpaid vested amounts or benefits under the compensation, incentive and benefit plans of the
Company in which Employee participates, and (iii) reimbursement for all reasonable and necessary expenses incurred by Employee in connection with his performance of services on behalf of the Company in accordance with applicable Company
policies and guidelines, in each case as of the effective date of such separation from service (the “Accrued Compensation”). Employee will be allowed to exercise his vested stock options to purchase Company common stock, if
any, during the time period set forth in, and in accordance with, the Plan and governing stock option agreement(s), including a “net exercise” of such stock options if Employee so elects. 

10.2 Separation from Service without Cause or for Good Reason Prior to a Change in Control. In the event of the
Employee’s separation from service from the Company without Cause or for Good Reason, and provided that Employee delivers to the Company a signed settlement agreement and general release of claims in favor of the Company in the form attached
hereto as Exhibit B (the “Release”), and satisfies all conditions to make the Release effective, within sixty (60) days following Employee’s separation from service, then, in addition to the Accrued
Compensation, Employee shall be entitled to the following: 
 (a) Lump sum payment equal to eighteen (18) months of
Employee’s then current Base Salary; 
 (b) Lump sum payment equal to Employee’s then applicable annual Target Bonus,
calculated at full attainment; 
 (c) Provided Employee timely elects to continue health coverage under COBRA, reimbursement for any
monthly COBRA premium payments made by Employee in the Twelve (12) months following Employee’s separation from service\; and 

(d) Acceleration as to 100% of Employee’s unvested equity awards from the Company. 

  
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 10.3 Separation from Service Following a Change in Control. In the
event of the Employee’s separation from service from the Company without Cause or for Good Reason, in each case within Twelve (12) months following a Change in Control, and provided that Employee delivers to the Company the signed Release,
and satisfies all conditions to make the Release effective, within sixty (60) days following Employee’s separation from service, then, in addition to the Accrued Compensation, Employee shall be entitled to the benefits as set forth below:

 (a) Lump sum payment equal to eighteen (18) months of Employee’s then current Base Salary; 

(b) Lump sum payment equal to Employee’s then applicable Target Bonus for eighteen (18) months, calculated at full
attainment; 
 (c) Provided Employee timely elects to continue health coverage under COBRA, reimbursement for any monthly COBRA
premium payments made by Employee in the eighteen (18) months following Employee’s separation from service\; and 
 (d)
Acceleration as to 100% of Employee’s unvested equity awards from the Company. 
 For the avoidance of doubt, the severance payments and benefits
payable pursuant to Section 10.2 or Section 10.3 above are not cumulative. Such lump sum severance payment shall be paid upon the later of thirty days after Employee’s employment is terminated or the date that Employee provides the
release described above and satisfies all conditions to make the Release effective; provided, that all such payments shall be made no later than March 15 of the year following the year in which the Employee’s employment is terminated. In
addition, if the COBRA reimbursements would violate any applicable statutes or regulations at the time of payment, the Company may, in its discretion, provide for a single lump sum and taxable payment of the value of such payments. 

10.4 Parachute Payments. In the event that the severance and other benefits provided for in this Agreement or otherwise
payable to the Employee (i) constitute “parachute payments” within the meaning of Section 280G of the Code and (ii) but for this Section, would be subject to the excise tax imposed by Section 4999 of the Code, then, at
Employee’s discretion, Employee’s severance and other benefits under this Agreement shall be payable either (i) in full, or (ii) as to such lesser amount which would result in no portion of such severance and other benefits being
subject to the excise tax under Section 4999 of the Code, whichever of the foregoing amounts, taking into account the applicable federal, state and local income taxes and the excise tax imposed by Section 4999, results in the receipt by
Employee on an after-tax basis, of the greatest amount of severance benefits under this Agreement, notwithstanding that all or some portion of such severance benefits may be taxable under
Section 4999 of the Code. Any reduction shall be made in the following manner: first a pro rata reduction of (i) cash payments subject to Section 409A of the Code as deferred compensation and (ii) cash payments not subject
to Section 409A of the Code, and second a pro rata cancellation of (i) equity-based compensation subject to Section 409A of the Code as deferred compensation and (ii) equity-based compensation not subject to Section 409A of
the Code. Reduction in either cash payments or equity compensation benefits shall be made prorata between and among benefits which are subject to Section 409A of the Code and benefits which are exempt from Section 409A of the Code. Unless
the Company and Employee otherwise agree in writing, any determination required under this Section shall be made in writing by the Company’s independent public accountants (the “Accountants”), whose determination shall
be conclusive and binding upon Employee and the Company for all purposes. For purposes of making the calculations required by this Section, the Accountants may make reasonable assumptions and approximations concerning applicable taxes and may
rely on reasonable, good faith interpretations concerning the application of Sections 280G and 4999 of the Code. The Company and Employee shall furnish to the Accountants such information and documents as the Accountants may reasonably request
in order to make a determination under this Section. The Company shall bear all costs the Accountants may reasonably incur in connection with any calculations contemplated by this Section. 

  
 4 

 10.5 Company Property. The parties acknowledge that Employee is utilizing a
Company provided computer, smartphone, and other electronic devices (the “Company Electronics”). Such devices shall become the property of the Employee on termination of employment for any reason subject to the following:
within ten (10) days of Employee’s termination of employment, Employee shall deliver the Company Electronics to the Company for removal of all Company property and data from the Company Electronics. The removal of Company data and files
from the Company Electronics shall be completed within two (2) business days unless the parties mutually agree to an extension. Employee’s personal data and files shall be preserved on the Company Electronics which will be returned to
Employee. Each party agrees to keep the other’s data and files confidential in connection with the transfer of the Company Electronics. 

11. Miscellaneous. This Agreement and the rights and obligations of the parties hereto shall be governed by and construed
and enforced in accordance with the laws of the State of Texas without regard to conflicts of laws principles. Resolution of any disputes under this Agreement shall only be held in courts in Travis County, Texas, and the parties expressly consent to
personal jurisdiction in courts in Travis County, Texas and waive any objections to such jurisdiction. In addition, Employee agrees that any party may also petition the court for injunctive relief where either party alleges or claims a violation of
this Agreement. 
 11.1 Indemnification. The Company shall indemnify Employee with respect to activities in connection
with his employment hereunder to the fullest extent provided in the Company’s bylaws.    Employee will be named as an insured on the director and officer liability insurance policy currently maintained, or as may be
maintained by the Company from time to time, and, in addition, Employee will enter into the form of indemnification agreement provided to other similarly situated executive officers and directors of the Company. 

11.2 Section 409A. To the extent (a) any payments or benefits to which
Employee becomes entitled under this Agreement, or under any agreement or plan referenced herein, in connection with Employee’s termination of employment with the Company constitute deferred compensation subject to Section 409A of the Code
and (b) Employee is deemed at the time of such termination of employment to be a “specified employee” under Section 409A of the Code, then such payments shall not be made or commence until the earliest of (i) the expiration
of the six (6)-month period measured from the date of Employee’s “separation from service” (as such term is at the time defined in Treasury Regulations under Section 409A of the Code) from the Company; or (ii) the date of
Employee’s death following such separation from service; provided, however, that such deferral shall only be effected to the extent required to avoid adverse tax treatment to Employee, including (without limitation) the additional twenty
percent (20%) tax for which Employee would otherwise be liable under Section 409A(a)(1)(B) of the Code in the absence of such deferral. Upon the expiration of the applicable deferral period, any payments which would have otherwise been made
during that period (whether in a single sum or in installments) in the absence of this paragraph shall be paid to Employee or Employee’s beneficiary in one lump sum (without interest). Any termination of Employee’s employment is intended
to constitute a “separation from service” as such term is defined in Treasury Regulation Section 1.409A-1. It is intended that each installment of the payments provided hereunder constitute
separate “payments” for purposes of Treasury Regulation Section 1.409A-2(b)(2)(i). It is further intended that payments hereunder satisfy, to the greatest extent possible, the exemption from the
application of Code Section 409A (and any state law of similar effect) provided under Treasury Regulation Section 1.409A-1(b)(4) (as a “short-term deferral”). 

11.3 Severability. If any provision of this Agreement shall be found by any arbitrator or court of competent
jurisdiction to be invalid or unenforceable, then the parties hereby waive such provision to the extent of its invalidity or unenforceability, and agree that all other provisions in this Agreement shall continue in full force and effect. 

11.4 No Waiver. The failure by either party at any time to require performance or compliance by the other of any of
its obligations or agreements shall in no way affect the right to require such performance or compliance at any time thereafter. The waiver by either party of a breach of any provision hereof shall not be taken or held to be a waiver of any
preceding or succeeding breach of such provision or as a waiver of the provision itself. No waiver of any kind shall be effective or binding, unless it is in writing and is signed by the party against whom such waiver is sought to be enforced. 

  
 5 

 11.5 Assignment. This Agreement and all rights hereunder are personal
to Employee and may not be transferred or assigned by Employee at any time. The Company may assign its rights, together with its obligations hereunder, to any parent, subsidiary, affiliate or successor, or in connection with any sale, transfer or
other disposition of all or substantially all of its business and assets, provided, however, that any such assignee assumes the Company’s obligations hereunder. 

11.6 Withholding. All sums payable to Employee hereunder shall be in United States Dollars and shall be reduced by
all federal, state, local and other withholding and similar taxes and payments required by applicable law. 
 11.7 Entire
Agreement. This Agreement (and the exhibit(s) hereto) constitutes the entire and only agreement and understanding between the parties relating to Employee’s employment with Company. This Agreement supersedes and cancels any and
all previous contracts, arrangements or understandings with respect to Employee’s employment. 
 11.8
Amendment. The parties understand and agree that this Agreement may not be amended, modified or waived, in whole or in part, expect in a writing approved by the Company’s Board of Directors and signed on behalf of the
Company. 
 11.9 Notices. All notices, if any, and all other communications, if any, required or permitted under
this Agreement shall be in writing and hand delivered, sent via facsimile, sent by registered first class mail, postage pre-paid, or sent by nationally recognized express courier service. Such notices and
other communications shall be effective upon receipt if hand delivered or sent via facsimile, five (5) days after mailing if sent by mail, and one (l) day after dispatch if sent by express courier, to the following addresses, or such other
addresses as any party shall notify the other parties: 
  

							
		 	If to the Company:	  	 Genprex, Inc.
 100 Congress Avenue, Suite
2000
 Austin, TX 78701
	  	
				
		 	              Attention:	  	Chief Financial Officer	  	
				
		 	     If to Employee:	  	 Rodney Varner
 115 Laura Lane

Austin, Texas 78746
	  	

 11.10 Binding Nature. This Agreement shall be binding upon, and inure to the
benefit of, the successors and personal representatives of the respective parties hereto. 
 11.11 Counterparts.
This Agreement may be executed in two or more counterparts, each of which shall be deemed to be an original but all of which, taken together, constitute one and the same agreement. 

11.12 Governing Law. This Agreement and the rights and obligations of the parties hereto shall be construed in
accordance with the laws of the State of Texas, without giving effect to the principles of conflict of laws. 

  
 6 

 11.13 Attorneys’ Fees. In the event of any claim, demand or suit
arising out of or with respect to this Agreement, the prevailing party shall be entitled to reasonable costs and attorneys’ fees, including any such costs and fees upon appeal. 

11.14 Effective Date. This Agreement will become effective on the date that it has been signed by Employee and the Company
and the Company closes an initial public offering of its securities (“Effective Date”). 

  
 7 

 IN WITNESS WHEREOF, the Company and Employee have executed this Agreement as of the date first
above written. 
  

					
	GENPREX, INC.	 		  	RODNEY VARNER
			
	  
	 	            	  	      

			
	
Print Name:                
                                         
                        
	 		  	
Print Name:                
                                         
                

			
	
Its:                  
                                         
                                  
	 		  	

  
 8 

 EXHIBIT A 

GENPREX, INC. 

CONFIDENTIAL INFORMATION, ASSIGNMENT OF INVENTIONS 

AND NONCOMPETITION AGREEMENT 

In consideration of new or continued employment with Genprex, Inc., a Delaware corporation, its subsidiaries, affiliates, predecessors,
successors or assigns (together the “Company”), and for other consideration, the receipt and sufficiency of which are hereby acknowledged, I agree to the following: 

1. Confidential Information. 

(a) Company Information. I agree at all times during the term of my employment and thereafter, to hold in strictest confidence, and not
to use, except for the exclusive benefit of the Company, or to disclose to any person, firm or entity without written authorization of an authorized officer of the Company (other than myself), any Confidential Information of the Company. I
understand that “Confidential Information” means any non-public information that relates to the actual or anticipated business or research and development of the Company, Company
proprietary information, technical data, trade secrets or know-how, including, but not limited to, research plans, research results, processes, methods, compositions, business plans, marketing plans, product
plans, products, services, suppliers, customer lists and customers (including, but not limited to, customers of the Company on whom I call or with whom I become acquainted during the term of my service on behalf of the Company), markets, software,
specifications, inventions, operations, procedures, compilations of data, technology, designs, finances or other business information disclosed to me by the Company either directly or indirectly in writing, orally or by drawings or observation. I
further understand that Confidential Information does not include any of the foregoing items that has become publicly known and made generally available through no wrongful act of mine or of others who were under confidentiality obligations as to
the item or items involved. 
 (b) Acknowledgments. I acknowledge that during my employment with the Company, I will have access to
Confidential Information, all of which shall be made accessible to me only in strict confidence; that unauthorized disclosure of Confidential Information will damage the Company’s business; and that the restrictions contained in this agreement
are reasonable and necessary for the protection of the Company’s legitimate business interests. 
 (c) Former Employer
Information. I agree that I will not, during my employment with the Company, improperly use or disclose any proprietary information or trade secrets of any former or concurrent employer or other person or entity and that I will not bring onto
the premises of the Company any unpublished document or proprietary information belonging to any such employer, person or entity. 
 (d)
Third-Party Information. I recognize that the Company has received and in the future will receive from third parties their confidential or proprietary information subject to a duty on the Company’s part to maintain the confidentiality of
such information and to use it only for certain limited purposes. I agree to hold all such confidential or proprietary information in the strictest confidence and not to disclose it to any person, firm or corporation or to use it except as necessary
in carrying out my work for the Company consistent with the Company’s agreement with such third party. 

  
 9 

 2. Inventions. 

(a) Inventions Retained and Licensed (Shop Rights). I have attached hereto, as Exhibit A, a list describing all inventions,
original works of authorship, developments, improvements, and trade secrets which were made by me prior to my employment with the Company which belong to me, which relate to the Company’s proposed business, products or research and development,
and which are not assigned to the Company hereunder (collectively referred to as “Prior Inventions”). If no such list is attached, I represent that there are no such Prior Inventions. If, in the course of my employment with
the Company, I incorporate into a Company product, process or service a Prior Invention owned by me or in which I have an interest, the Company is hereby granted and shall have a nonexclusive, royalty-free, irrevocable, perpetual, worldwide license
to make, have made, modify, use and sell such Prior Invention as part of or in connection with such product, process or service, and to practice any method related thereto. 

(b) Assignment of Inventions. I agree that I will promptly make full written disclosure to the Company, will hold in trust for the sole
right and benefit of the Company, will assign to the Company or its designee, and hereby do assign to the Company or its designee, all my right, title, and interest in and to any and all inventions, original works of authorship, developments,
concepts, improvements, designs, discoveries, ideas, trademarks or trade secrets, whether or not patentable or registrable under copyright or similar laws, which I have solely or jointly conceived or developed or reduced to practice, or caused to be
conceived or developed or reduced to practice and which I may solely or jointly conceive or develop or reduce to practice, or cause to be conceived or developed or reduced to practice, during the period of time I have been and am in the employ of
the Company or prior to my employment with the Company when working with, for, or on behalf of the Company in a capacity other than as an employee (collectively referred to as “Inventions”), except as provided in
Section 2(f) below. I further acknowledge that all original works of authorship which are made by me (solely or jointly with others) within the scope of and during the period of my employment with the Company and which are
protectable by copyright are and shall be treated as “works made for hire” as that term is defined in the United States Copyright Act. I understand and agree that the decision whether or not to commercialize or market any Invention
developed by me solely or jointly with others is within the Company’s sole discretion and for the Company’s sole benefit and that no royalty will be due to me as a result of the Company’s efforts to commercialize or market any such
Invention. 
 (c) Inventions Assigned to the United States. I agree to assign to the United States government all my right, title, and
interest in and to any and all Inventions whenever such full title is required to be in the United States by a contract between the Company and the United States or any of its agencies. 

(d) Maintenance of Records. I agree to keep and maintain adequate and current written records of all Inventions made by me (solely or
jointly with others) during the term of my employment with the Company. The records will be in the form of notes, drawings and any other format that may be specified by the Company. The records will be available to and remain the sole property of
the Company at all times. 
 (e) Patent and Copyright Registrations. I agree to assist the Company, or its designee, at the
Company’s expense, in every proper way to secure the Company’s rights in the Inventions and any copyrights, patents, trademarks, trade secrets, mask work rights or other intellectual property rights relating thereto in any and all
countries, including the disclosure to the Company of all pertinent information and data with respect thereto, the execution of all applications, specifications, oaths, assignments and all other instruments which the Company shall deem necessary in
order to apply for and obtain such rights and in order to assign and convey to the Company, its successors, assigns, and nominees the sole and exclusive rights, title and interest in and to such Inventions, and any copyrights, patents, trademarks,
trade secrets, mask work rights or other intellectual property rights relating thereto. I further agree that my obligation to execute or cause to be executed, when it is in my power to do so, any such instrument or papers shall continue after the
termination of this Agreement. If the Company is unable because of my mental or physical incapacity or for any other reason to secure my signature to apply for or to pursue any application for any United States or foreign patents, trademarks or
copyright registrations covering Inventions or original works of authorship assigned to the Company above, then I hereby irrevocably designate and appoint the Company and its duly authorized officers and agents as my agent and attorney in fact, to
act for and in my behalf and stead to execute and file any such applications and to do all other lawfully permitted acts to further the prosecution and issuance of letters patent, trademarks or copyright registrations thereon with the same legal
force and effect as if executed by me. 

  
 10 

 (f) No Self-Help or Unauthorized Code. I represent and warrant to the Company, that I will
not knowingly infect, incorporate into or combine with any computer system, computer program, software product, database or computer storage media of the Company, except as known to and intended by the Company’s senior management, any
Unauthorized Code (as defined below). 
 “Unauthorized Code” means any back door, time bomb, drop dead device, virus,
Trojan horse, worm, or other harmful routing, code, algorithm or hardware component designed or used: (i) to disable, erase, alter or harm any computer system, computer program, database, data, hardware or communications system, automatically,
with the passage of time, or under the control of any person, or (ii) to access any computer system, computer program, database, data, hardware or communications system. 

3. Conflicting Employment. I agree that, during the term of my employment with the Company, I will not engage in any other employment,
occupation, consulting or other business activity directly related to the business in which the Company is now involved or becomes involved during the term of my employment, nor will I engage in any other activities that conflict with my obligations
to the Company. 
 4. Returning Company Documents. I agree that, at the time of leaving the employ of the Company, I will deliver to
the Company (and will not keep in my possession, recreate, copy or deliver to anyone else) any and all devices, documents, records, data, notes, reports, proposals, lists, correspondence, formulae, specifications, drawings, materials, equipment or
property, or reproductions of any aforementioned items, developed by me pursuant to my employment with the Company or otherwise belonging to the Company. I understand and agree that compliance with this paragraph may require that data be removed
from my personal computer equipment, and I agree to give the qualified personnel of the Company or its contractors access to such computer equipment for that purpose. 

5. Notification of New Employer. In the event that I leave the employ of the Company, I hereby grant consent to notification by the
Company to my new employer about my rights and obligations under this Agreement. 
 6. Solicitation of Employees. I agree that for a
period of twelve (12) months immediately following the termination of my relationship with the Company for any reason, I shall not either directly or indirectly solicit, induce, recruit or encourage any of the Company’s employees to leave
their employment, or take away such employees, either for myself or for any other person or entity. 
 7. Covenant Not to Compete.

 (a) Covenant. I agree that during the course of my employment and for twelve (12) months following the termination of my
relationship with the Company (the “Noncompetition Period”) for any reason, I will not, without the prior written consent of the Company, (i) serve as a partner, employee, consultant, officer, director, manager, agent,
associate, investor, or (ii) directly or indirectly, own, purchase, organize or take preparatory steps for the organization of, or (iii) build, design, finance, acquire, lease, operate, manage, invest in, work or consult for or otherwise
affiliate myself with any business, (a) in competition with the Company’s business at the time my relationship with the Company terminated or (b) competing in any other line of business that I knew or had reason to know the Company
had formed an intention to enter. This covenant shall not prohibit me from owning less than one percent of the securities of any company that is publicly traded on a nationally recognized stock exchange. The foregoing covenant shall cover my
activities in every part of the Territory in which I may conduct business during the term of such covenant as set forth above. “Territory” shall mean (i) all counties in the State of Texas, (ii) all other states of
the United States of America and (iii) all other countries of the world; provided that, with respect to clauses (ii) and (iii), the Company maintains non-trivial operations, facilities, or
customers in such geographic area prior to the date of the termination of my relationship with the Company. 

  
 11 

 (b) Acknowledgement. I acknowledge that my fulfillment of the obligations contained in
this Agreement is necessary to protect the Company’s Confidential Information and to preserve the trade secrets, value and goodwill of the Company. I further acknowledge the time, geographic and scope limitations of my obligations under
subsection (a) above are reasonable, especially in light of the Company’s desire to protect its Confidential Information and trade secrets, and that I will not be precluded from gainful employment if I am obligated not to compete with the
Company during the period and within the Territory as described above. 
 (c) Severability. The covenants contained in subsection
(a) above shall be construed as a series of separate covenants, one for each county, state and country of any geographic area in the Territory. Except for geographic coverage, each such separate covenants shall be deemed identical in terms to
the covenant contained in subsection (a) above. If, in any judicial proceeding, a court refuses to enforce any of such separate covenants (or any part thereof), then such unenforceable covenant (or such part) shall be eliminated from this
Agreement to the extent necessary to permit the remaining separate covenants (or portions thereof) to be enforced. In the event the provisions of subsection (a) are deemed to exceed the time, geographic or scope limitations permitted by law,
then such provisions shall be reformed to the maximum time, geographic or scope limitations, as the case may be, then permitted by law. 
 8.
Representations. I agree to execute any proper oath or verify any proper document required to carry out the terms of this Agreement. I represent that my performance of all the terms of this Agreement will not breach any agreement to keep in
confidence proprietary information acquired by me in confidence or in trust prior to my employment by the Company. I have not entered into, and I agree I will not enter into, any oral or written agreement in conflict herewith. 

9. Equitable Relief. I acknowledge that the Company’s Confidential Information is unique and that breach of my covenant of
confidentiality contained in this Agreement will cause irreparable damage to the Company that is difficult to quantify in monetary terms. Accordingly, I consent to the Company obtaining equitable or injunctive relief against any threatened or actual
breach of the terms of this Agreement without posting a bond or other security and I hereby waive any right to argue that the Company has an adequate remedy at law. 

10. At-Will Employment. I UNDERSTAND AND ACKNOWLEDGE THAT MY EMPLOYMENT WITH THE COMPANY IS FOR
AN UNSPECIFIED DURATION AND CONSTITUTES “AT-WILL” EMPLOYMENT. I ALSO UNDERSTAND THAT ANY REPRESENTATION TO THE CONTRARY IS UNAUTHORIZED AND NOT VALID UNLESS OBTAINED IN WRITING AND SIGNED BY THE
PRESIDENT OF THE COMPANY. I ACKNOWLEDGE THAT THIS EMPLOYMENT RELATIONSHIP MAY BE TERMINATED AT ANY TIME, WITH OR WITHOUT GOOD CAUSE OR FOR ANY OR NO CAUSE, AT THE OPTION EITHER OF THE COMPANY OR MYSELF, WITH OR WITHOUT NOTICE. 

11. General Provisions. 

(a) Governing Law; Consent to Personal Jurisdiction. This Agreement will be governed by the laws of the state of Texas without regard
for conflicts of laws principles. I hereby expressly consent to the exclusive personal jurisdiction of the state and federal courts located in Texas for any lawsuit filed there against me by the Company arising from or relating to this Agreement.

 (b) Entire Agreement. This Agreement sets forth the entire agreement and understanding between the Company and me relating to the
subject matter herein and supersedes all prior discussions between us. No modification of or amendment to this Agreement, nor any waiver of any rights under this Agreement, will be effective unless in writing signed by the party to be charged. Any
subsequent change or changes in my duties, salary or compensation will not affect the validity or scope of this Agreement. 

  
 12 

 (c) Other Agreements. In the event of any direct conflict between any term of this
Agreement and any term of any other agreement executed by me, the terms of this Agreement shall control. If I signed or sign any other agreement(s) relating to or arising from my employment with the company, all provisions of such agreement(s) that
do not directly conflict with a provision of this Agreement shall not be affected, modified or superseded by this Agreement, but rather shall remain fully enforceable according to their terms.. 

(d) Severability. If one or more of the provisions in this Agreement are deemed void by law, then the remaining provisions will continue
in full force and effect, and, with respect to the covenant not to compete in Section 7, the court is hereby authorized to reduce the duration or geographic scope of such covenant as may be required so that in its reduced form the provision is
enforceable to the fullest extent of the law. 
 (e) Survival. My obligations under this Agreement shall survive the termination of my
employment with the Company and shall thereafter be enforceable whether or not such termination is claimed or found to be wrongful or to constitute or result in a breach of any contract or of any other duty owed or claimed to be owed to me by the
Company or any Company employee, agent or contractor. 
 (f) Successors and Assigns. This Agreement will be binding upon my heirs,
executors, administrators and other legal representatives and will be for the benefit of the Company, its successors, and its assigns. 
 (g)
Construction. The language used in this Agreement will be deemed to be the language chosen by the parties to express their mutual intent and no rules of strict construction will be applied against either party. 

(h) Counterparts. This Agreement may be executed in any number of counterparts, each of which shall be enforceable, and all of which
together shall constitute one agreement. 
 12. Acknowledgment. I acknowledge and agree to each of the following items: 

(a) I am executing this Agreement voluntarily and without any duress or undue influence by the Company or anyone else; and 

(b) I have carefully read this Agreement. I have asked any questions needed for me to understand the terms, consequences and binding effect of
this Agreement and fully understand them; and 
 (c) I sought the advice of an attorney of my choice if I wanted to before signing this
Agreement. 
 Executed on this         day of
                                , 20        .

  

			
	EMPLOYEE
		
	By:	 	 
	Print Name:	 	  

	
	GENPREX, INC.
		
	By:	 	  

	Print Name:	 	  

  
 13 

 EXHIBIT A 

LIST OF PRIOR INVENTIONS 
 AND
ORIGINAL WORKS OF AUTHORSHIP 
  

					
	 Title
	  	 Date
	  	 Identifying Number or Brief Description

          No inventions or improvements 

         Additional Sheets Attached 

Signature of Employee:
                                         
                
 Print Name of
Employee:                                       
                

Date:                         
                                         
                     

  
 14 

 EXHIBIT B 

GENERAL RELEASE AGREEMENT 

In consideration of the severance and acceleration benefits (the “Severance and Acceleration Benefits”) offered to me by
Genprex, Inc. ( “Employer”) pursuant to my Employment Agreement with Employer dated [                    ], (the
“Agreement”) and in connection with the termination of my employment, I agree to the following general release (the “Release”). 
  

	 	1.	On behalf of myself, my heirs, executors, administrators, successors, and assigns, I hereby fully and forever generally release and discharge Employer, its current, former and future parents, subsidiaries, affiliated
companies, related entities, employee benefit plans, and their fiduciaries, predecessors, successors, officers, directors, shareholders, agents, employees and assigns (collectively, the “Company”) from any and all claims, causes of
action, and liabilities up through the date of my execution of the Release. The claims subject to this release include, but are not limited to, those relating to my employment with Employer and/or any predecessor or successor to Employer and the
termination of such employment. All such claims (including related attorneys’ fees and costs) are barred without regard to whether those claims are based on any alleged breach of a duty arising in statute, contract, or tort. This expressly
includes waiver and release of any rights and claims arising under any and all laws, rules, regulations, and ordinances, including, but not limited to: Title VII of the Civil Rights Act of 1964; the Older Workers Benefit Protection Act; the
Americans With Disabilities Act; the Age Discrimination in Employment Act; the Fair Labor Standards Act; the National Labor Relations Act; the Family and Medical Leave Act; the Employee Retirement Income Security Act of 1974, as amended
(“ERISA”); the Workers Adjustment and Retraining Notification Act; the Equal Pay Act of 1963; and any similar law of any other state or governmental entity. 

2. This Release does not extend to, and has no effect upon, any benefits that have accrued, and to which I have become vested,
under any employee benefit plan within the meaning of ERISA sponsored by the Company. 
 3. In understanding the terms of the
Release and my rights, I have been advised to consult with an attorney of my choice prior to executing the Release. I understand that nothing in this Release is intended to constitute an unlawful release or waiver of any of my rights under any laws
and/or to prevent, impede, or interfere with my ability and/or rights, if any: (a) under applicable workers’ compensation laws; (b) to seek unemployment benefits; (c) to file a charge or complaint with a government agency such as
but not limited to the Equal Employment Opportunity Commission, the National Labor Relations Board, or any applicable state agency; (d) provide truthful testimony if under subpoena to do so, (e) file a claim with any state or federal
agency or to participate or cooperate in such a matter, and/or (f) to challenge the validity of this release. Furthermore, notwithstanding any provisions and covenants herein, the Release shall not waive (a) any rights to indemnification I
may have as an officer of Employer or otherwise in connection with my employment with Employer, under Employer’s bylaws or other governing instruments or any agreement addressing such subject matter between Employer and me or under any merger
or acquisition agreement addressing such subject matter, (b) any obligations owed to me pursuant to the Agreement, (c) my rights of insurance under any liability policy covering Employer’s officers, or (d) any accrued but unpaid
wages; any reimbursement for business expenses pursuant to Employer’s policies for such reimbursements, any outstanding claims for benefits or payments under any benefit plans of Employer or subsidiaries, any accrued but unused vacation, any
ongoing agreements evidencing outstanding equity awards granted to me, any obligations owed to me pursuant to the terms of outstanding written agreements between myself and Employer and any claims I may not release as a matter of law, including
indemnification claims under applicable law. 

  
 15 

 4. I understand and agree that Employer will not provide me with the Severance
and Acceleration Benefits unless I execute the Release. I also understand that I have received or will receive, regardless of the execution of the Release, all wages owed to me together with any accrued but unused vacation pay, less applicable
withholdings and deductions, earned through my termination date. 
 5. As part of my existing and continuing obligations to
Employer, I have returned to Employer all documents (and all copies thereof) and other property belonging to Employer that I have had in my possession at any time, including but not limited to files, notes, drawings, records, business plans and
forecasts, financial information, specification, computer-recorded information, tangible property (including, but not limited to, computers, laptops, pagers, etc.), credit cards, entry cards, identification badges and keys; and any materials of any
kind which contain or embody any proprietary or confidential information of Employer (and all reproductions thereof). I understand that, even if I did not sign the Release, I am still bound by any and all confidential/proprietary/trade secret
information, non-disclosure and inventions assignment agreement(s) signed by me in connection with my employment with Employer, or with a predecessor or successor of Employer, pursuant to the terms of such
agreement(s). 
 6. I represent and warrant that I am the sole owner of all claims relating to my employment with Employer
and/or with any predecessor of Employer, and that I have not assigned or transferred any claims relating to my employment to any other person or entity. 

7. I agree to keep the Severance and Acceleration Benefits and the provisions of this Release confidential and not to reveal
their contents to anyone except my lawyer, my spouse or other immediate family member, and/or my financial consultant, or as required by legal process or applicable law. 

8. I understand and agree that the Release shall not be construed at any time as an admission of liability or wrongdoing by
either the Company or me. 
 9. I understand and agree that the Release shall not be construed at any time as an admission of
liability or wrongdoing by either the Company or myself. 
 10. I agree that I will not make any negative or disparaging
statements or comments, either as fact or as opinion, about the Company, its employees, officers, directors, shareholders, vendors, products or services, business, technologies, market position or performance. Nothing in this paragraph shall
prohibit me from providing truthful information in response to a subpoena or other legal process. 
 11. Any controversy or
any claim arising out of or relating to the interpretation, enforceability or breach of the Release shall be settled in the courts of Texas in accordance with the Agreement. 

12. I agree that I have had at least twenty-one (21) calendar days in which to
consider whether to execute the Release, no one hurried me into executing the Release during that period, and no one coerced me into executing the Release. I understand that the offer of the Severance and Acceleration Benefits and the Release shall
expire on the twenty-second (22nd) calendar day after my employment termination date if I have not accepted it by that time. I further understand that Employer’s obligations under the Release
shall not become effective or enforceable 

  
 16 

 
until the eighth (8th) calendar day after the date I sign the Release provided that I have timely delivered it to Employer (the
“Effective Date”) and that in the seven (7) day period following the date I deliver a signed copy of the Release to Employer I understand that I may revoke my acceptance of the Release. I understand that the Severance and
Acceleration Benefits will become available to me on or about the fourteenth (14th) calendar day after the Effective Date. 

13. In executing the Release, I acknowledge that I have not relied upon any statement made by Employer, or any of its
representatives or employees, with regard to the Release unless the representation is specifically included herein. Furthermore, the Release and the Agreement contain our entire understanding regarding eligibility for and the payment of severance
benefits and supersede any or all prior representations and agreements regarding the subject matter. Once effective and enforceable, this agreement can only be changed by another written agreement signed by me and an authorized representative of
Employer. 
 14. Should any provision of the Release be determined by an arbitrator, court of competent jurisdiction, or
government agency to be wholly or partially invalid or unenforceable, the legality, validity and enforceability of the remaining parts, terms, or provisions are intended to remain in full force and effect. Specifically, should a court, arbitrator,
or agency conclude that a particular claim may not be released as a matter of law, it is the intention of the parties that the general release and the waiver of unknown claims above shall otherwise remain effective to release any and all other
claims. I acknowledge that I have obtained sufficient information to intelligently exercise my own judgment regarding the terms of the Release before executing the Release. 

[SIGNATURE PAGE TO GENERAL RELEASE AGREEMENT
FOLLOWS] 

  
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 EXECUTIVE’S ACCEPTANCE OF RELEASE 

BEFORE SIGNING MY NAME TO THE RELEASE, I STATE THE FOLLOWING: I HAVE READ THE RELEASE, I UNDERSTAND IT AND I KNOW THAT I AM GIVING UP IMPORTANT RIGHTS. I
HAVE OBTAINED SUFFICIENT INFORMATION TO INTELLIGENTLY EXERCISE MY OWN JUDGMENT. I HAVE BEEN ADVISED THAT I SHOULD CONSULT WITH AN ATTORNEY BEFORE SIGNING IT, AND I HAVE SIGNED THE RELEASE KNOWINGLY AND VOLUNTARILY. 

Date delivered to employee
                        ,               
 . 
 Executed this
                     day of
                        ,             . 

 

	
	  

	Signature
	
	  

	Name (Please Print)

 [SIGNATURE PAGE TO GENERAL
RELEASE AGREEMENT] 

  
 18

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