Document:

Intellectual Property Security Agreement between St. Bernard Software, Inc.

 Exhibit 10.5 
 INTELLECTUAL PROPERTY SECURITY AGREEMENT 
 This Intellectual Property Security Agreement (this
“IP Agreement”) is made as of the 25th day of January, 2008 by and between ST. BERNARD SOFTWARE, INC. (“Grantor”), and Silicon Valley Bank (“Bank”). 
 RECITAL 
 Bank will make credit extensions to Grantor as described in Loan and
Security Agreement dated as of May 11, 2007 as amended by that certain First Amendment to Loan and Security Agreement dated as of July 9, 2007, that certain Second Amendment to Loan and Security Agreement dated as of August 13, 2007
and that certain Third Amendment to Loan and Security Agreement dated as of the date hereof (as further amended, restated, or otherwise modified, the “Loan Agreement”), but only if Grantor grants Bank a security interest in its Copyrights,
Trademarks, Patents, and Mask Works. Defined terms used but not defined herein shall have the same meanings as in the Loan Agreement. 
 NOW, THEREFORE, for good and valuable consideration, receipt of which is hereby acknowledged and intending to be legally bound, as collateral security for the prompt and complete payment when due of Grantor’s Obligations under
the Loan Agreement, Grantor hereby represents, warrants, covenants and agrees as follows: 
 1. Grant of Security Interest. As
collateral security for the prompt and complete payment and performance of all of Grantor’s present or future Indebtedness, obligations and liabilities to Bank, Grantor hereby grants a security interest in all of Grantor’s right, title and
interest in, to and under its intellectual property (all of which shall collectively be called the “Intellectual Property Collateral”), including, without limitation, the following: 
 (a) Any and all copyright rights, copyright applications, copyright registrations and like protections in each work or authorship and
derivative work thereof, whether published or unpublished and whether or not the same also constitutes a trade secret, now or hereafter existing, created, acquired or held, including without limitation those set forth on Exhibit A attached
hereto (collectively, the “Copyrights”); 
 (b) Any and all trade secrets, and any and all intellectual property
rights in computer software and computer software products now or hereafter existing, created, acquired or held; 
 (c) Any
and all design rights that may be available to Grantor now or hereafter existing, created, acquired or held; 
 (d) All
patents, patent applications and like protections including, without limitation, improvements, divisions, continuations, renewals, reissues, extensions and continuations-in-part of the same, including without limitation the patents and patent
applications set forth on Exhibit B attached hereto (collectively, the “Patents”); 
 (e) Any trademark and
servicemark rights, whether registered or not, applications to register and registrations of the same and like protections, and the entire goodwill of the business of Grantor connected with and symbolized by such trademarks, including without
limitation those set forth on Exhibit C attached hereto (collectively, the “Trademarks”); 
 (f) All mask
works or similar rights available for the protection of semiconductor chips, now owned or hereafter acquired, including, without limitation those set forth on Exhibit D attached hereto (collectively, the “Mask Works”); 

 (g) Any and all claims for damages by way of past, present and future infringements of
any of the rights included above, with the right, but not the obligation, to sue for and collect such damages for said use or infringement of the intellectual property rights identified above; 
 (h) All licenses or other rights to use any of the Copyrights, Patents, Trademarks, or Mask Works and all license fees and royalties
arising from such use to the extent permitted by such license or rights; 
 (i) All amendments, extensions, renewals and
extensions of any of the Copyrights, Trademarks, Patents, or Mask Works; and 
 (j) All proceeds and products of the
foregoing, including without limitation all payments under insurance or any indemnity or warranty payable in respect of any of the foregoing. 
 2. Authorization and Request. Grantor authorizes and requests that the Register of Copyrights and the Commissioner of Patents and Trademarks record this IP Agreement. 
 3. Covenants and Warranties. Grantor represents, warrants, covenants and agrees as follows: 
 (a) Grantor is now the sole owner of the Intellectual Property Collateral, except for non-exclusive licenses granted by Grantor in the
ordinary course of business; 
 (b) Performance of this IP Agreement does not conflict with or result in a breach of any other
agreement covering the Intellectual Property Collateral to which Grantor is bound, except to the extent that such other intellectual property agreements prohibit the assignment of the rights thereunder to a third party without the licensor’s or
other party’s consent; 
 (c) During the term of this IP Agreement, Grantor will not transfer or otherwise encumber any
interest in the Intellectual Property Collateral, except for Permitted Liens; 
 (d) Each of the Patents is valid and
enforceable, and no part of the Intellectual Property Collateral has been judged invalid or unenforceable, in whole or in part, and, to Grantor’s knowledge, no claim has been made that any part of the Intellectual Property Collateral violates
the rights of any third party; 
 (e) Grantor shall promptly advise Bank of any material adverse change in the composition of
the Intellectual Property Collateral, including but not limited to any subsequent ownership right of the Grantor in or to any Trademark, Patent, Copyright, or Mask Work specified in this IP Agreement; 
 (f) Grantor shall (i) protect, defend and maintain the validity and enforceability of the Trademarks, Patents, Copyrights, and Mask
Works, (ii) use its best efforts to detect infringements of the Trademarks, Patents, Copyrights, and Mask Works and promptly advise Bank in writing of material infringements detected and (iii) not allow any Trademarks, Patents, Copyrights,
or Mask Works to be abandoned, forfeited or dedicated to the public without the written consent of Bank, which shall not be unreasonably withheld, unless Grantor determines that reasonable business practices suggest that abandonment is appropriate;

 (g) Grantor shall not register any Copyrights or Mask Works with the United States Copyright Office unless it: (i) has
given at least fifteen (15) days’ prior notice to Bank of its intent to register such Copyrights or Mask Works and has provided Bank with a copy of the application it intends to file with the United States Copyright Office (excluding
exhibits thereto); (ii) executes a security agreement or such other documents as Bank may reasonably request in order to maintain the perfection and priority of Bank’s security interest in the Copyrights proposed to be registered with the
United States Copyright 

  

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Office; and (iii) records such security documents with the United States Copyright Office contemporaneously with filing the Copyright application(s)
with the United States Copyright Office. Grantor shall promptly provide to Bank a copy of the Copyright application(s) filed with the United States Copyright Office, together with evidence of the recording of the security documents necessary for
Bank to maintain the perfection and priority of its security interest in such Copyrights or Mask Works. Grantor shall provide written notice to Bank of any application filed by Grantor in the United States Patent Trademark Office for a patent or to
register a trademark or service mark within thirty (30) days of any such filing; 
 (h) This IP Agreement creates, and in
the case of after acquired Intellectual Property Collateral, this IP Agreement will create at the time Grantor first has rights in such after acquired Intellectual Property Collateral, in favor of Bank a valid and perfected first priority security
interest in the Intellectual Property Collateral in the United States securing the payment and performance of the obligations evidenced by the Loan Agreement upon making the filings referred to in clause (i) below; 
 (i) To its knowledge (except for, and upon, the filing with the United States Patent and Trademark office with respect to the Patents and
Trademarks and the Register of Copyrights with respect to the Copyrights and Mask Works necessary to perfect the security interests created hereunder, and except as has been already made or obtained) no authorization, approval or other action by,
and no notice to or filing with, any U.S. governmental authority or U.S. regulatory body is required either (i) for the grant by Grantor of the security interest granted hereby or for the execution, delivery or performance of this IP Agreement
by Grantor in the U.S. or (ii) for the perfection in the United States or the exercise by Bank of its rights and remedies thereunder; 
 (j) All information heretofore, herein or hereafter supplied to Bank by or on behalf of Grantor with respect to the Intellectual Property Collateral is accurate and complete in all material respects; 
 (k) Grantor shall not enter into any agreement that would materially impair or conflict with Grantor’s obligations hereunder without
Bank’s prior written consent, which consent shall not be unreasonably withheld. Grantor shall not permit the inclusion in any material contract to which it becomes a party of any provisions that could or might in any way prevent the creation of
a security interest in Grantor’s rights and interest in any property included within the definition of the Intellectual property Collateral acquired under such contracts, except that certain contracts may contain anti-assignment provisions that
could in effect prohibit the creation of a security interest in such contracts; and 
 (l) Upon any executive officer of
Grantor obtaining actual knowledge thereof, Grantor will promptly notify Bank in writing of any event that materially adversely affects the value of any Intellectual Property Collateral, the ability of Grantor to dispose of any Intellectual Property
Collateral or the rights and remedies of Bank in relation thereto, including the levy of any legal process against any of the Intellectual Property Collateral. 
 4. Bank’s Rights. Bank shall have the right, but not the obligation, to take, at Grantor’s sole expense, any actions that Grantor is required to take under this IP Agreement but which Grantor fails to
take. Grantor shall reimburse and indemnify Bank for all costs and reasonable expenses incurred in the exercise of its rights under this section 4. 
 5. Inspection Rights. Grantor hereby grants to Bank and its employees, representatives and agents the right to visit, during reasonable hours upon prior reasonable notice to Grantor, any of Grantor’s plants and facilities that
manufacture, install or store products (or that have done so during the prior six-month period) that are sold utilizing any of the Intellectual Property Collateral, and to inspect the products and quality control records relating thereto upon
reasonable written notice to Grantor and as often as may be reasonably requested; provided, however, nothing herein shall entitle Bank access to Grantor’s trade secrets and other proprietary information. 
  

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 6. Further Assurances; Attorney in Fact. 
 (a) On a continuing basis, Grantor will, subject to any prior licenses, encumbrances and restrictions and prospective licenses, make,
execute, acknowledge and deliver, and file and record in the proper filing and recording places in the United States, all such instruments, including appropriate financing and continuation statements and collateral agreements and filings with the
United States Patent and Trademarks Office and the Register of Copyrights, and take all such action as may reasonably be deemed necessary or advisable, or as requested by Bank, to perfect Bank’s security interest in all Copyrights, Patents,
Trademarks, and Mask Works and otherwise to carry out the intent and purposes of this IP Agreement, or for assuring and confirming to Bank the grant or perfection of a security interest in all Intellectual Property Collateral. 
 (b) Grantor hereby irrevocably appoints Bank as Grantor’s attorney-in-fact, with full authority in the place and stead of Grantor and
in the name of Grantor, Bank or otherwise, from time to time in Bank’s discretion, upon Grantor’s failure or inability to do so, to take any action and to execute any instrument which Bank may deem necessary or advisable to accomplish the
purposes of this IP Agreement, including: 
 (i) To modify, in its sole discretion, this IP Agreement without first obtaining
Grantor’s approval of or signature to such modification by amending Exhibit A, Exhibit B, Exhibit C, and Exhibit D hereof, as appropriate, to include reference to any right, title or interest in any Copyrights, Patents, Trademarks or Mask Works
acquired by Grantor after the execution hereof or to delete any reference to any right, title or interest in any Copyrights, Patents, Trademarks, or Mask Works in which Grantor no longer has or claims any right, title or interest; and 
 (ii) To file, in its sole discretion, one or more financing or continuation statements and amendments thereto, relative to any of the
Intellectual Property Collateral without the signature of Grantor where permitted by law. 
 7. Events of Default. The occurrence of
any of the following shall constitute an Event of Default under this IP Agreement: 
 (a) An Event of Default occurs under the
Loan Agreement; or 
 (b) Grantor breaches any warranty or agreement made by Grantor in this IP Agreement. 
 8. Remedies. Upon the occurrence and continuance of an Event of Default, Bank shall have the right to exercise all the remedies of a secured party
under the California Uniform Commercial Code, including without limitation the right to require Grantor to assemble the Intellectual Property Collateral and any tangible property in which Bank has a security interest and to make it available to Bank
at a place designated by Bank. Bank shall have a nonexclusive, royalty free license to use the Copyrights, Patents, Trademarks, and Mask Works to the extent reasonably necessary to permit Bank to exercise its rights and remedies upon the occurrence
of an Event of Default. Grantor will pay any expenses (including reasonable attorney’s fees) incurred by Bank in connection with the exercise of any of Bank’s rights hereunder, including without limitation any expense incurred in disposing
of the Intellectual Property Collateral. All of Bank’s rights and remedies with respect to the Intellectual Property Collateral shall be cumulative. 
 9. Indemnity. Grantor agrees to defend, indemnify and hold harmless Bank and its officers, employees, and agents against: (a) all obligations, demands, claims, and liabilities claimed or asserted by any
other party in connection with the transactions contemplated by this IP Agreement, and (b) all losses or expenses in any way suffered, incurred, or paid by Bank as a result of or in any way arising out of, following or consequential to
transactions between Bank and Grantor, whether under this IP Agreement or otherwise (including without limitation, reasonable attorneys fees and reasonable expenses), except for losses arising from or out of Bank’s gross negligence or willful
misconduct. 
  

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 10. Reassignment. At such time as Grantor shall completely satisfy all of the obligations secured
hereunder, Bank shall execute and deliver to Grantor all deed, assignments, and other instruments as may be necessary or proper to reinvest in Grantor full title to the property assigned hereunder, subject to any disposition thereof which may have
been made by Bank pursuant hereto. 
 11. Course of Dealing. No course of dealing, any failure to exercise, or any delay in exercising
any right, power or privilege hereunder shall operate as a waiver thereof. 
 12. Attorneys’ Fees. If any action relating to this
IP Agreement is brought by either party hereto against the other party, the prevailing party shall be entitled to recover reasonable attorneys’ fees, costs and disbursements. 
 13. Amendments. This IP Agreement may be amended only by a written instrument signed by both parties hereto. 
 14. Counterparts. This IP Agreement may be executed in two or more counterparts, each of which shall be deemed an original but all of which
together shall constitute the same instrument. 
 15. Law and Jurisdiction. This IP Agreement shall be governed by and construed in
accordance with the laws of the State of California, without regard for choice of law provisions. Grantor and Bank consent to the nonexclusive jurisdiction of any state or federal court located in California. 
 16. Confidentiality. In handling any confidential information, Bank shall exercise the same degree of care that it exercises with respect to its
own proprietary information of the same types to maintain the confidentiality of any non-public information thereby received or received pursuant to this IP Agreement except that the disclosure of this information may be made (i) to the
affiliates of the Bank, (ii) to prospective transferee or purchasers of an interest in the obligations secured hereby, (iii) as required by law, regulation, rule or order, subpoena judicial order or similar order and (iv) as may be
required in connection with the examination, audit or similar investigation of Bank. 
 IN WITNESS WHEREOF, the parties hereto have executed
this IP Agreement on the day and year first above written. 
  

									
	Address of Grantor:	 		 	GRANTOR:
			
	15015 Avenue of Science
San Diego, CA 92128	 		 	ST. BERNARD SOFTWARE, INC.
					
		 		 		 	By:	 	/s/ Vince Rossi
					
		 		 		 	Name:	 	Vincent A. Rossi
					
		 		 		 	Title:	 	CEO

  

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 Exhibit “A” attached to that certain Intellectual Property Security Agreement dated January __, 2008.

 EXHIBIT “A” 
 COPYRIGHTS 
 EXHIBIT A - ISSUED COPYRIGHTS 
  

					
	 COPYRIGHT
 DESCRIPTION
	  	REGISTRATION
NUMBER	  	DATE OF
ISSUANCE
	 None
	  		  	

 EXHIBIT B - PENDING COPYRIGHT APPLICATIONS 
  

									
	 COPYRIGHT DESCRIPTION
	  	APPLICATION NUMBER	  	DATE OF
FILING	  	CREATION	  	FIRST DATE OF PUBLIC
DISTRIBUTION
					
	None	  		  		  		  	

  

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 Exhibit “B” attached to that certain Intellectual Property Security Agreement dated January __, 2008.

 EXHIBIT “B” 
 PATENTS

  

											
	 PATENT DESCRIPTION
	  	DOCKET NO.	  	COUNTRY	  	SERIAL NO.	  	FILING DATE	  	STATUS
	 None
	  		  		  		  		  	

  

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 Exhibit “C” attached to that certain Intellectual Property Security Agreement dated January __, 2008.

 EXHIBIT “C” 
 TRADEMARKS 
  

									
	 	  	 TRADEMARK DESCRIPTION
	  	 COUNTRY
	  	SERIAL NO./
REG. NO	  	 STATUS

	1.	  	EPRISM	  	U.S.	  	Ser. 78298124	  	Live-Registered on Principal Register on 6/7/2005
	2.	  	SYSTEM ACTIVITY MANAGER	  	U.S.	  	Ser. 75525443	  	Live-Registered on Supplemental Register on 8/1/2000
	3.	  	IPRISM	  	U.S.	  	Ser. 75823687	  	 Live-Registered on Principal Register on 9/11/2001
 Assignment recorded to St. Bernard

	4.	  	ST. BERNARD	  	U.S.	  	Ser. 78/613,844	  	 Live-Pending registration on Principal Register
 Filing date: 4/21/2005

	5.	  	LIVEPRISM	  	U.S.	  	Ser. 77/084,182	  	Intent to use filed on January 16, 2007
	6.	  	SECURITYEXPERT	  	U.S.	  	Ser. 78432280	  	
	7.	  	UPDATEEXPERT	  	U.S.	  	Ser. 76242914	  	
	8.	  	OPEN FILE MANAGER	  	U.S.	  	Ser. 75270628	  	

  

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 Exhibit “D” attached to that certain Intellectual Property Security Agreement dated January __, 2008.

 EXHIBIT “D” 
 MASK
WORKS 
  

									
	 MASK WORK DESCRIPTION
	  	COUNTRY	  	SERIAL NO.	  	REG. NO	  	STATUS
	 None
	  		  		  		  	

  

 9Indemnification Agreement

 Exhibit 10.1 
 INDEMNIFICATION AGREEMENT 
 This Agreement is made as of the 29th day of January 2008, by and between
Curis, Inc., a Delaware corporation (the “Corporation”), and Stephen K. Carter (the “Indemnitee”), a director of the Corporation. 
 WHEREAS, it is essential to the Corporation to retain and attract as directors and officers the most capable persons available, and 
 WHEREAS, the substantial increase in corporate litigation subjects directors and officers to expensive litigation risks at the same time that the availability of directors’ and officers’ liability
insurance has been severely limited, and 
 WHEREAS, it is now and has always been the express policy of the Corporation to indemnify
its directors and officers, and 
 WHEREAS, the Indemnitee does not regard the protection available under the Corporation’s
Certificate of Incorporation and insurance as adequate in the present circumstances, and may not be willing to serve or continue to serve as a director without adequate protection, and 
 WHEREAS, the Corporation desires the Indemnitee to serve, or continue to serve, as a director of the Corporation. 
 NOW THEREFORE, the Corporation and the Indemnitee do hereby agree as follows: 
 1. Agreement to Serve. The Indemnitee agrees to serve or continue to serve as a director of the Corporation for so long as the Indemnitee is duly
elected or appointed or until such time as the Indemnitee tenders a resignation in writing. 
 2. Definitions. As used in this
Agreement: 
 (a) The term “Proceeding” shall include any threatened, pending or completed action, suit, arbitration, alternative
dispute resolution proceeding, administrative hearing or other proceeding, whether brought by or in the right of the Corporation or otherwise and whether of a civil, criminal, administrative or investigative nature, and any appeal therefrom.

 (b) The term “Corporate Status” shall mean the status of a person who is or was a director or officer of the Corporation, or is
or was serving, or has agreed to serve, at the request of the Corporation, as a director, officer, partner, trustee, member, employee or agent of another corporation, partnership, joint venture, trust, limited liability company or other enterprise.

 (c) The term “Expenses” shall include, without limitation, attorneys’ fees, retainers, court costs, transcript costs, fees
and expenses of experts, travel expenses, duplicating costs, printing and binding costs, telephone charges, postage, delivery service fees and other disbursements or expenses of the types customarily incurred in connection with investigations,

 
judicial or administrative proceedings or appeals, but shall not include the amount of judgments, fines or penalties against Indemnitee or amounts paid in
settlement in connection with such matters. 
 (d) References to “other enterprise” shall include employee benefit plans;
references to “fines” shall include any excise tax assessed with respect to any employee benefit plan; references to “serving at the request of the Corporation” shall include any service as a director, officer, employee or agent
of the Corporation which imposes duties on, or involves services by, such director, officer, employee, or agent with respect to an employee benefit plan, its participants, or beneficiaries; and a person who acted in good faith and in a manner such
person reasonably believed to be in the interests of the participants and beneficiaries of an employee benefit plan shall be deemed to have acted in a manner “not opposed to the best interests of the Corporation” as referred to in this
Agreement. 
 3. Indemnification in Third-Party Proceedings. The Corporation shall indemnify the Indemnitee in accordance with the
provisions of this Paragraph 3 if the Indemnitee was or is a party to or threatened to be made a party to or otherwise involved in any Proceeding (other than a Proceeding by or in the right of the Corporation to procure a judgment in its favor)
by reason of the Indemnitee’s Corporate Status or by reason of any action alleged to have been taken or omitted in connection therewith, against all Expenses, judgments, fines, penalties and amounts paid in settlement actually and reasonably
incurred by or on behalf of the Indemnitee in connection with such Proceeding, if the Indemnitee acted in good faith and in a manner which the Indemnitee reasonably believed to be in, or not opposed to, the best interests of the Corporation and,
with respect to any criminal Proceeding, had no reasonable cause to believe that his or her conduct was unlawful. The termination of any Proceeding by judgment, order, settlement, conviction or upon a plea of nolo contendere or its
equivalent, shall not, of itself, create a presumption that the Indemnitee did not act in good faith and in a manner which the Indemnitee reasonably believed to be in, or not opposed to, the best interests of the Corporation, and, with respect to
any criminal Proceeding, had reasonable cause to believe that his or her conduct was unlawful. 
 4. Indemnification in Proceedings by or
in the Right of the Corporation. The Corporation shall indemnify the Indemnitee in accordance with the provisions of this Paragraph 4 if the Indemnitee was or is a party to or threatened to be made a party to or otherwise involved in any
Proceeding by or in the right of the Corporation to procure a judgment in its favor by reason of the Indemnitee’s Corporate Status or by reason of any action alleged to have been taken or omitted in connection therewith, against all Expenses
and, to the extent permitted by law, amounts paid in settlement actually and reasonably incurred by or on behalf of the Indemnitee in connection with such Proceeding, if the Indemnitee acted in good faith and in a manner which the Indemnitee
reasonably believed to be in, or not opposed to, the best interests of the Corporation, except that no indemnification shall be made under this Paragraph 4 in respect of any claim, issue, or matter as to which the Indemnitee shall have been
adjudged to be liable to the Corporation, unless, and only to the extent, that the Court of Chancery of Delaware or the court in which such action or suit was brought shall determine upon application that, despite the adjudication of such liability
but in view of all the circumstances of the case, the Indemnitee is fairly and reasonably entitled to indemnity for such Expenses as the Court of Chancery or such other court shall deem proper. 

 5. Exceptions to Right of Indemnification. Notwithstanding anything to the contrary in this
Agreement, except as set forth in Paragraph 10, the Corporation shall not indemnify the Indemnitee in connection with a Proceeding (or part thereof) initiated by the Indemnitee unless the initiation thereof was approved by the Board of
Directors of the Corporation. Notwithstanding anything to the contrary in this Agreement, the Corporation shall not indemnify the Indemnitee to the extent the Indemnitee is reimbursed from the proceeds of insurance, and in the event the Corporation
makes any indemnification payments to the Indemnitee and the Indemnitee is subsequently reimbursed from the proceeds of insurance, the Indemnitee shall promptly refund such indemnification payments to the Corporation to the extent of such insurance
reimbursement. 
 6. Indemnification of Expenses of Successful Party. Notwithstanding any other provision of this Agreement, to the
extent that the Indemnitee has been successful, on the merits or otherwise, in defense of any Proceeding or in defense of any claim, issue or matter therein, the Indemnitee shall be indemnified against all Expenses incurred by or on behalf of the
Indemnitee in connection therewith. Without limiting the foregoing, if any Proceeding or any claim, issue or matter therein is disposed of, on the merits or otherwise (including a disposition without prejudice), without (i) the disposition
being adverse to the Indemnitee, (ii) an adjudication that the Indemnitee was liable to the Corporation, (iii) a plea of guilty or nolo contendere by the Indemnitee, (iv) an adjudication that the Indemnitee did not act
in good faith and in a manner the Indemnitee reasonably believed to be in or not opposed to the best interests of the Corporation, and (v) with respect to any criminal proceeding, an adjudication that the Indemnitee had reasonable cause to
believe his or her conduct was unlawful, the Indemnitee shall be considered for the purposes hereof to have been wholly successful with respect thereto. 
 7. Notification and Defense of Claim. As a condition precedent to the Indemnitee’s right to be indemnified, the Indemnitee must notify the Corporation in writing as soon as practicable of any Proceeding
for which indemnity will or could be sought. With respect to any Proceeding of which the Corporation is so notified, the Corporation will be entitled to participate therein at its own expense and/or to assume the defense thereof at its own expense,
with legal counsel reasonably acceptable to the Indemnitee. After notice from the Corporation to the Indemnitee of its election so to assume such defense, the Corporation shall not be liable to the Indemnitee for any legal or other expenses
subsequently incurred by the Indemnitee in connection with such Proceeding, other than as provided below in this Paragraph 7. The Indemnitee shall have the right to employ his or her own counsel in connection with such Proceeding, but the fees
and expenses of such counsel incurred after notice from the Corporation of its assumption of the defense thereof shall be at the expense of the Indemnitee unless (i) the employment of counsel by the Indemnitee has been authorized by the
Corporation, (ii) counsel to the Indemnitee shall have reasonably concluded that there may be a conflict of interest or position on any significant issue between the Corporation and the Indemnitee in the conduct of the defense of such
Proceeding or (iii) the Corporation shall not in fact have employed counsel to assume the defense of such Proceeding, in each of which cases the fees and expenses of counsel for the Indemnitee shall be at the expense of the Corporation, except
as otherwise expressly provided by this Agreement. The Corporation shall not be entitled, without the consent of the Indemnitee, to assume the defense of any claim brought by or in the right of the Corporation or as to which counsel for the
Indemnitee shall have reasonably made the conclusion provided for in clause (ii) above. The Corporation shall not be required to indemnify the Indemnitee under 

 
this Agreement for any amounts paid in settlement of any Proceeding effected without its written consent. The Corporation shall not settle any Proceeding in
any manner which would impose any penalty or limitation on the Indemnitee without the Indemnitee’s written consent. Neither the Corporation nor the Indemnitee will unreasonably withhold or delay their consent to any proposed settlement.

 8. Advancement of Expenses. Subject to the provisions of Paragraph 9 of this Agreement, in the event that the Corporation does
not assume the defense pursuant to Paragraph 7 of this Agreement of any Proceeding of which the Corporation receives notice under this Agreement, any Expenses incurred by or on behalf of the Indemnitee in defending such Proceeding shall be paid
by the Corporation in advance of the final disposition of such Proceeding; provided, however, that the payment of such Expenses incurred by or on behalf of the Indemnitee in advance of the final disposition of such Proceeding shall be
made only upon receipt of an undertaking by or on behalf of the Indemnitee to repay all amounts so advanced in the event that it shall ultimately be determined that the Indemnitee is not entitled to be indemnified by the Corporation as authorized in
this Agreement. Such undertaking shall be accepted without reference to the financial ability of the Indemnitee to make repayment. 
 9.
Procedure for Indemnification. In order to obtain indemnification or advancement of Expenses pursuant to Paragraphs 3, 4, 6 or 8 of this Agreement, the Indemnitee shall submit to the Corporation a written request. Any such indemnification or
advancement of Expenses shall be made promptly, and in any event within 30 days after receipt by the Corporation of the written request of the Indemnitee, unless with respect to requests under Paragraphs 3, 4 or 8 the Corporation determines within
such 30-day period that the Indemnitee did not meet the applicable standard of conduct set forth in Paragraph 3 or 4, as the case may be. Such determination, and any determination that advanced Expenses must be repaid to the Corporation, shall
be made in each instance (a) by a majority vote of the directors of the Corporation consisting of persons who are not at that time parties to the Proceeding (“disinterested directors”), whether or not a quorum, (b) by a committee
of disinterested directors designated by a majority vote of disinterested directors, whether or not a quorum, (c) if there are no disinterested directors, or if the disinterested directors so direct, by independent legal counsel (who may, to
the extent permitted by applicable law, be regular legal counsel to the Corporation) in a written opinion, or (d) by the stockholders of the Corporation. 
 10. Remedies. The right to indemnification or advancement of Expenses as provided by this Agreement shall be enforceable by the Indemnitee in any court of competent jurisdiction. Unless otherwise required by
law, the burden of proving that indemnification is not appropriate shall be on the Corporation. Neither the failure of the Corporation to have made a determination prior to the commencement of such action that indemnification is proper in the
circumstances because the Indemnitee has met the applicable standard of conduct, nor an actual determination by the Corporation pursuant to Paragraph 9 that the Indemnitee has not met such applicable standard of conduct, shall be a defense to
the action or create a presumption that the Indemnitee has not met the applicable standard of conduct. The Indemnitee’s expenses (of the type described in the definition of “Expenses” in Paragraph 2(c)) reasonably incurred in
connection with successfully establishing the Indemnitee’s right to indemnification, in whole or in part, in any such Proceeding shall also be indemnified by the Corporation. 

 11. Partial Indemnification. If the Indemnitee is entitled under any provision of this Agreement
to indemnification by the Corporation for some or a portion of the Expenses, judgments, fines, penalties or amounts paid in settlement actually and reasonably incurred by or on behalf of the Indemnitee in connection with any Proceeding but not,
however, for the total amount thereof, the Corporation shall nevertheless indemnify the Indemnitee for the portion of such Expenses, judgments, fines, penalties or amounts paid in settlement to which the Indemnitee is entitled. 
 12. Subrogation. In the event of any payment under this Agreement, the Corporation shall be subrogated to the extent of such payment to all of the
rights of recovery of the Indemnitee, who shall execute all papers required and take all action necessary to secure such rights, including execution of such documents as are necessary to enable the Corporation to bring suit to enforce such rights.

 13. Term of Agreement. This Agreement shall continue until and terminate upon the later of (a) six years after the date that
the Indemnitee shall have ceased to serve as a director of the Corporation or, at the request of the Corporation, as a director, officer, partner, trustee, member, employee or agent of another corporation, partnership, joint venture, trust, limited
liability company or other enterprise or (b) the final termination of all Proceedings pending on the date set forth in clause (a) in respect of which the Indemnitee is granted rights of indemnification or advancement of Expenses hereunder
and of any proceeding commenced by the Indemnitee pursuant to Paragraph 10 of this Agreement relating thereto. 
 14. Indemnification
Hereunder Not Exclusive. The indemnification and advancement of Expenses provided by this Agreement shall not be deemed exclusive of any other rights to which the Indemnitee may be entitled under the Certification of Incorporation, the By-Laws,
any other agreement, any vote of stockholders or disinterested directors, the General Corporation Law of Delaware, any other law (common or statutory), or otherwise, both as to action in the Indemnitee’s official capacity and as to action in
another capacity while holding office for the Corporation. Nothing contained in this Agreement shall be deemed to prohibit the Corporation from purchasing and maintaining insurance, at its expense, to protect itself or the Indemnitee against any
expense, liability or loss incurred by it or the Indemnitee in any such capacity, or arising out of the Indemnitee’s status as such, whether or not the Indemnitee would be indemnified against such expense, liability or loss under this
Agreement; provided that the Corporation shall not be liable under this Agreement to make any payment of amounts otherwise indemnifiable hereunder if and to the extent that the Indemnitee has otherwise actually received such payment under any
insurance policy, contract, agreement or otherwise. 
 15. No Special Rights. Nothing herein shall confer upon the Indemnitee any
right to continue to serve as a director of the Corporation for any period of time or at any particular rate of compensation. 
 16.
Savings Clause. If this Agreement or any portion thereof shall be invalidated on any ground by any court of competent jurisdiction, then the Corporation shall nevertheless indemnify the Indemnitee as to Expenses, judgments, fines, penalties
and amounts paid in settlement with respect to any Proceeding to the full extent permitted by any applicable portion of this Agreement that shall not have been invalidated and to the fullest extent permitted by applicable law. 

 17. Counterparts. This Agreement may be executed in any number of counterparts, each of which
shall constitute the original. 
 18. Successors and Assigns. This Agreement shall be binding upon the Corporation and its successors
and assigns and shall inure to the benefit of the estate, heirs, executors, administrators and personal representatives of the Indemnitee. 
 19. Headings. The headings of the paragraphs of this Agreement are inserted for convenience only and shall not be deemed to constitute part of this Agreement or to affect the construction thereof. 
 20. Modification and Waiver. This Agreement may be amended from time to time to reflect changes in Delaware law or for other reasons. No
supplement, modification or amendment of this Agreement shall be binding unless executed in writing by both of the parties hereto. No waiver of any of the provisions of this Agreement shall be deemed or shall constitute a waiver of any other
provision hereof nor shall any such waiver constitute a continuing waiver. 
 21. Notices. All notices, requests, demands and other
communications hereunder shall be in writing and shall be deemed to have been given (i) when delivered by hand or (ii) if mailed by certified or registered mail with postage prepaid, on the third day after the date on which it is so
mailed: 
  

							
	(a)	  	if to the Indemnitee, to:	  	 Stephen K. Carter
 263 West End Avenue,
 New York City, New York 10023
	  	
				
	(b)	  	if to the Corporation, to:	  	 Curis, Inc.
 45 Moulton Street
 Cambridge, Massachusetts 02138
 Attn: President
	  	
				
		  	with a copy to:	  	 Wilmer Cutler Pickering Hale and Dorr LLP
 60
State Street
 Boston, Massachusetts 02109
 Attn: Steven D.
Singer, Esq.
	  	

 or to such other address as may have been furnished to the Indemnitee by the Corporation or to the Corporation by
the Indemnitee, as the case may be. 
 22. Applicable Law. This Agreement shall be governed by, and construed and enforced in
accordance with, the laws of the State of Delaware. The Indemnitee may elect to have the right to indemnification or reimbursement or advancement of Expenses interpreted on the basis of the applicable law in effect at the time of the occurrence of
the event or events giving rise to the applicable Proceeding, to the extent permitted by law, or on the basis of the applicable law in effect at the time such indemnification or reimbursement or advancement of Expenses is 

 
sought. Such election shall be made, by a notice in writing to the Corporation, at the time indemnification or reimbursement or advancement of Expenses is
sought; provided, however, that if no such notice is given, and if the General Corporation Law of Delaware is amended, or other Delaware law is enacted, to permit further indemnification of the directors and officers, then the
Indemnitee shall be indemnified to the fullest extent permitted under the General Corporation Law, as so amended, or by such other Delaware law, as so enacted. 
 23. Enforcement. The Corporation expressly confirms and agrees that it has entered into this Agreement in order to induce the Indemnitee to continue to serve as a director of the Corporation, and acknowledges
that the Indemnitee is relying upon this Agreement in continuing in such capacity. 
 24. Entire Agreement. This Agreement sets forth
the entire agreement of the parties hereto in respect of the subject matter contained herein and supercedes all prior agreements, whether oral or written, by any officer, employee or representative of any party hereto in respect of the subject
matter contained herein; and any prior agreement of the parties hereto in respect of the subject matter contained herein is hereby terminated and cancelled. For avoidance of doubt, the parties confirm that the foregoing does not apply to or limit
the Indemnitee’s rights under Delaware law or the Corporation’s Certificate of Incorporation or By-Laws. 
 25. Consent to
Suit. In the case of any dispute under or in connection with this Agreement, the Indemnitee may only bring suit against the Corporation in the Court of Chancery of the State of Delaware. The Indemnitee hereby consents to the exclusive
jurisdiction and venue of the courts of the State of Delaware, and the Indemnitee hereby waives any claim the Indemnitee may have at any time as to forum non conveniens with respect to such venue. The Corporation shall have the right to institute
any legal action arising out of or relating to this Agreement in any court of competent jurisdiction. Any judgment entered against either of the parties in any proceeding hereunder may be entered and enforced by any court of competent jurisdiction.

 [Remainder of Page Intentionally Left Blank] 

 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be duly executed as of the
day and year first above written. 
  

			
	CURIS, INC.
		
	By:	 	 /s/ Michael P. Gray

	Name:	 	Michael P. Gray
	Title:	 	Chief Financial Officer
	
	INDEMNITEE
	
	 /s/ Stephen K. Carter

	Stephen K. Carter

 [Signature Page to Indemnification Agreement]

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