Document:

WAIVER TO CREDIT AGREEMENT, DATED AS OF MARCH 15, 2012

 Exhibit 10.16 
 WAIVER AGREEMENT 
 THIS WAIVER AGREEMENT (this
“Agreement”), dated as of March 15, 2012, is entered into by and among INFUSYSTEM HOLDINGS, INC., a Delaware corporation (“Holdings”), INFUSYSTEM, INC., a California corporation (“InfuSystem”), and
FIRST BIOMEDICAL, INC., a Kansas corporation (“FBI” and together with Holdings and InfuSystem, the “Borrowers” and each individually a “Borrower”), BANK OF AMERICA, N.A. in its capacity as an
Administrative Agent and as a Lender (“Agent”) and the other lenders party hereto (collectively, together with Agent in its capacity as a Lender, the “Lenders”). 

WHEREAS, the Borrowers, Agent and the Lenders are parties to that certain Credit Agreement dated as of June 15, 2010 as
amended by (i) that certain First Amendment to Credit Agreement dated as of January 27, 2011, (ii) that certain Second Amendment to Credit Agreement dated as of April 1, 2011, (iii) that certain Third Amendment to Credit
Agreement dated as of May 20, 2011 and (iv) that certain Fourth Amendment to Credit Agreement dated as of July 21, 2011 (as so amended, the “Credit Agreement”); 

WHEREAS, Borrowers have advised Agent and the Lenders that Meson Capital Partners, Kleinheinz Capital Partners and Boston Avenue
Capital (collectively, the “Kleinheinz Dissident Group”) have (i) delivered to the Company, on behalf of stockholders having a majority of shares of the Company’s Common Stock, a demand that the Company call a special
meeting of the stockholders of Holdings at which they would seek to remove the seven members of the Board of Directors of Holdings and replace them with the Kleinheinz Dissident Group’s nominees and (ii) delivered notice to the Company of
the intent to nominate, and solicit proxies in support of, a competing slate of Director nominees, at the Company’s Annual Meeting (such proposed actions, together or separate, the “Board Replacement Proposal”); 

WHEREAS, without limiting any other Change of Control that may occur in connection with the actions of the Kleinheinz Dissident
Group, if stockholders of Holdings approve the Board Replacement Proposal and the Board Replacement Proposal is effected, a Change of Control would result therefrom, thereby constituting an Event of Default under Section 8.01(k) of the Credit
Agreement; 
 WHEREAS, it is anticipated that, solely as a result of the potential for a Change of Control and Event of
Default to occur resulting from an approval of the Board Replacement Proposal, auditing standard AU341 will require that the independent certified public accountant of the Borrowers issue a “going concern opinion” that will include an
explanatory paragraph (the “Explanatory Paragraph”) referenced to disclosure in the audited financial statements of Holdings and its Subsidiaries for the Fiscal Year ended December 31, 2011 which describe the possibility of a
Change of Control as a matter that raises substantial doubt about Holdings and its Subsidiaries ability to continue as a going concern (a “2011 Qualified Audit”); 

WHEREAS, Section 6.01(a) of the Credit Agreement requires the Borrowers to deliver audited financial statements of Holdings
and its Subsidiaries for each Fiscal Year which are audited and, among other things, are not subject to any “going concern” or like qualification or exception or any qualification or exception as to the scope of such audit; 

WHEREAS, in light of the foregoing requirement, delivery of a 2011 Qualified Audit would constitute an Event of Default under
Section 8.01(b) of the Credit Agreement (the “Designated Default”); 
 WHEREAS, notwithstanding the
foregoing, the Borrowers have requested that the Lenders prospectively waive the Designated Default, and Agent and the Lenders have agreed to prospectively waive the Designated Default subject to and on the terms and conditions set forth in this
Agreement; and 
 WHEREAS, as of the close of business March 14, 2012, the aggregate unpaid principal balance of the
Revolving Loans was $2,500,000; the aggregate amount of the L/C Obligations was $80,580, and the aggregate unpaid principal balance of the Term Loans was $24,000,000. 

 NOW, THEREFORE, in consideration of the premises and mutual agreements herein
contained, the parties hereto agree as follows. 
 SECTION 1 

DEFINED TERMS 
 Capitalized terms used but not defined herein shall have the meanings ascribed to such terms in the Credit Agreement. 
 SECTION 2 
 WAIVER 

In reliance upon the representations, warranties and covenants of the Borrowers contained herein, and subject to the effectiveness and
the terms and conditions of this Agreement, including, without limitation, those set forth in Section 4 hereof, Lenders hereby prospectively waive the Designated Default solely to the extent and on the condition, however, that: (i) any
2011 Qualified Audit which is delivered to Agent indicates with specificity and certainty (as determined by Agent) that it is subject to a “going concern opinion” qualification solely as a result of the possibility that the Board
Replacement Proposal will be approved by stockholders of Holdings, resulting in the occurrence of a Change of Control and hence an Event of Default (for the avoidance of doubt, the draft Explanatory Paragraph delivered to the Agent on March 14,
2012 establishes the foregoing requirement; provided that the foregoing waiver shall be deemed rescinded and of no effect if the final Explanatory Paragraph issued in the 2011 Qualified Audit is not in a form that is identical to such draft); and
(ii) no other Default shall exist as of the date on which such 2011 Qualified Audit is delivered to Agent. Other than with respect to the express and specific waiver of the Designated Default set forth above, the foregoing shall not (a) be
deemed a waiver of any Default which may now exist or which may occur after the date hereof, (b) establish a custom or course of dealing among Agent, the Lenders and the Borrowers, (c) operate as a waiver of any other right, power, or
remedy of Agent or the Lenders under the Credit Agreement, (d) be construed as an agreement or understanding by the Lenders to grant any other waiver or other accommodation in the future with respect to any provision of the Credit Agreement or
any of the other Loan Documents, or (e) modify any of the Borrowers’ obligations to comply with the covenants set forth in the Credit Agreement, including, without limitation, Section 6.01(a) thereof. For the avoidance of doubt, and
without limiting the generality of the immediately preceding sentence, nothing contained herein shall be construed waive, prejudice, impair or otherwise adversely affect any right, power or remedy of Agent or the Lenders as it relates to the Board
Replacement Proposal or, if it occurs, any Change of Control or resulting Event of Default, all of which rights, powers and remedies are hereby expressly reserved. 
 SECTION 3 
 REPRESENTATIONS AND WARRANTIES 

Each Borrower hereby represents and warrants to Agent and the Lenders that: 

3.1 Due Authorization, etc. The execution and delivery by it of this Agreement and the performance by it of its obligations
under the Credit Agreement are duly authorized by all necessary corporate action, do not require any filing or registration with or approval or consent of any governmental agency or authority, do not and will not conflict with, result in any
violation of or constitute any default under any provision of its certificate or articles of incorporation, as applicable, or by-laws or those of any of its Subsidiaries or any material agreement or other document binding upon or applicable to it or
any of its Subsidiaries (or any of their respective properties) or any material law or governmental regulation or court decree or order applicable to it or any of its Subsidiaries, and will not result in or require the creation or imposition of any
Lien in any of its properties or the properties of any of its Subsidiaries pursuant to the provisions of any agreement binding upon or applicable to it or any of its Subsidiaries. 

  
 -2-

 3.2 Validity. This Agreement has been duly executed and delivered by such
Borrower and, together with the Credit Agreement, are the legal, valid and binding obligations of such Borrower, enforceable against such Borrower in accordance with their respective terms subject, as to enforcement only, to bankruptcy, insolvency,
reorganization, moratorium or similar laws affecting the enforceability of the rights of creditors generally. 
 3.3
Representations and Warranties. The representations and warranties contained in Article V of the Credit Agreement are true and correct on the date of this Agreement in all material respects (except for those that are qualified by
“materiality” or “Material Adverse Effect”, in which case such representations and warranties shall have been true and correct in all respects), except to the extent (a) that such representations and warranties solely relate
to an earlier date or (b) have been changed by circumstances permitted by the Credit Agreement. 
 SECTION 4

 CONDITIONS PRECEDENT 
 The waiver set forth in Section 2 of this Agreement shall become effective upon satisfaction of all of the following conditions precedent: 

4.1 Receipt of Documents. Agent shall have received all of the following, each in form and substance satisfactory to Agent:

 (a) Amendment. Counterparts original of this Agreement duly executed by Borrowers and by the Required
Lenders; 
 (b) Secretary’s Certificate. A certificate of the secretary of each Borrower dated the
date hereof or such other date as shall be acceptable to Agent, substantially in the form of Exhibit A to this Agreement; and 
 (c) Guarantor Joinder. The joinder attached hereto duly executed by by IFC LLC (the “Guarantor”). 
 4.2 Waiver Fee. Agent shall have received from Borrowers a waiver fee in the amount of $72,500.00 to be allocated ratably among each Lender based on the Applicable Percentage of such
Lender’s Commitment. 
 4.3 Other Conditions. No Default shall have occurred and be continuing other than the
Designated Default. 
 Notwithstanding the foregoing, if this Agreement has not by its terms become effective on or before
March 15, 2012, this Agreement (other than Sections 5.6 and 5.7 hereof, which shall be and remain effective in any event) shall not become effective and shall be deemed of no further force and effect. 

SECTION 5 

MISCELLANEOUS 
 5.1 Warranties and Absence of Defaults. In order to induce Agent and Lenders to enter into this Agreement, Borrowers hereby warrant to Agent and each Lender, as of the date of the actual
execution of this Agreement and as of the date on which this Agreement becomes effective (a) no Default has occurred which is continuing as of such date other than the Designated Default and (b) the representations and warranties in
Section 3 of this Agreement are true and correct. 
 5.2 Documents Remain in Effect. Except as expressly
amended and modified by this Agreement, the Credit Agreement and the other documents executed pursuant to the Credit Agreement remain unmodified and in full force and effect, and each Borrower hereby ratifies, adopts and confirms its
representations, warranties, agreements and covenants contained in, and obligations and liabilities under, the Credit Agreement and the other documents executed pursuant to the Credit Agreement. 

  
 -3-

 5.3 Reference to Loan Agreement. On and after the effective date of this
Agreement, each reference in the Credit Agreement to “this Agreement,” “hereunder,” “hereof,” “herein” or words of like import, and each reference to the “Loan Agreement” in any Loan Documents, or
other agreements, documents or other instruments executed and delivered pursuant to the Credit Agreement, shall mean and be a reference to the Credit Agreement as supplemented by this Agreement; and this Agreement shall be deemed to be a Loan
Document. 
 5.4 Headings. Headings used in this Agreement are for convenience of reference only, and shall not
affect the construction of this Agreement. 
 5.5 Counterparts. This Agreement may be executed in any number of
counterparts, and by the parties hereto on the same or separate counterparts, and each such counterpart, when executed and delivered, shall be deemed to be an original, but all such counterparts shall together constitute but one and the same
Agreement. Any party hereto may execute and deliver a counterpart of this Agreement by delivering by facsimile or email transmission a signature page of this Agreement signed by such party, and any such facsimile or email signature shall be treated
in all respects as having the same effect as an original signature. Any party delivering by facsimile or email transmission a counterpart executed by it shall promptly thereafter also deliver a manually signed counterpart of this Agreement.

 5.6 Expenses. Borrowers agree, jointly and severally, to pay on demand all reasonable out-of-pocket
costs and expenses of Agent and each Lender (including reasonable fees, charges and disbursements of Agent’s and each Lender’s attorneys) in connection with the preparation, negotiation, execution, delivery and administration of this
Agreement and all other instruments or documents provided for herein or delivered or to be delivered hereunder or in connection herewith. In addition, Borrowers agree, jointly and severally, to pay, and save Agent and each Lender harmless from all
liability for, any stamp or other taxes which may be payable in connection with the execution or delivery of this Agreement, the borrowings under the Credit Agreement, and the execution and delivery of any instruments or documents provided for
herein or delivered or to be delivered hereunder or in connection herewith, in each case to the same extent required under the Credit Agreement. All obligations provided in this Section 5.6 shall survive any termination of this Agreement or the
Credit Agreement. 
 5.7 Confirmation of Obligations; Release. 

(a) Each Borrower (and by joinder hereto, the Guarantor) hereby confirms that the Borrowers are jointly and severally
indebted to the Lenders for the Loans and L/C Obligations in the amounts and as of the date set forth in last “Whereas” recital hereof, and is also obligated to the Lenders in respect of other Obligations as set forth in the Credit
Agreement and the other Loan Documents. Each Borrower (and by joinder hereto, the Guarantor) further acknowledges and agrees that as of the date hereof, it has no claim, defense or set-off right against any Lender or Agent of any nature whatsoever,
whether sounding in tort, contract or otherwise, and has no claim, defense or set-off of any nature whatsoever to the enforcement by any Lender or Agent of the full amount of the Loans and other obligations of the Borrowers and the Guarantor under
the Credit Agreement and the other Loan Documents. 
 (b) Notwithstanding the foregoing, to the extent that any
claim, cause of action, defense or set-off against any Lender or Agent or their enforcement of the Credit Agreement or any other Loan Document, of any nature whatsoever, known or unknown, fixed or contingent, does nonetheless exist or may exist on
the date hereof, in consideration of the Lenders’ and Agent’s entering into this Agreement, each Borrower (and by joinder hereto, the Guarantor) hereby irrevocably and unconditionally waives and releases fully each and every such claim,
cause of action, defense and set-off which exists or may exist on the date hereof. 
 (c) All obligations
provided in this Section 5.7 shall survive any termination of this Agreement or the Credit Agreement. 

  
 -4-

 5.8 Governing Law; Certain Other Matters. 

(a) This Agreement shall be a contract made under and governed by the internal laws of the State of Illinois. Wherever
possible, each provision of this Agreement shall be interpreted in such manner as to be effective and valid under applicable laws, but if any provision of this Agreement shall be prohibited by or invalid under such laws, such provisions shall be
ineffective only to the extent of such prohibition or invalidity, without invalidating the remainder of such provision or the remaining provisions of this Agreement. 

(b) This Agreement and all other agreements and documents executed in connection herewith have been prepared through the
joint efforts of all of the parties. Neither the provisions of this Agreement or any such other agreements and documents nor any alleged ambiguity shall be interpreted or resolved against any party on the ground that such party’s counsel
drafted this Agreement or such other agreements and documents, or based on any other rule of strict construction. Each of the parties hereto represents and declares that such party has carefully read this Agreement and all other agreements and
documents executed in connection herewith and therewith, and that such party knows the contents thereof and signs the same freely and voluntarily. The parties hereby acknowledge that they have been represented by legal counsel of their own choosing
in negotiations for and preparation of this Agreement and all other agreements and documents executed in connection therewith and that each of them has read the same and had their contents fully explained by such counsel and is fully aware of their
contents and legal effect. 
 5.9 Successors. This Agreement shall be binding upon Borrowers, Agent, each Lender
and their respective successors and assigns, and shall inure to the benefit of Borrowers, Agent, each Lender and the successors and assigns of Agent and such Lender. 
 5.10 Waiver of Jury Trial. EACH OF THE PARTIES TO THIS AGREEMENT HEREBY IRREVOCABLY WAIVES ALL RIGHT TO A TRIAL BY JURY IN ANY ACTION, PROCEEDING OR COUNTERCLAIM (WHETHER SOUNDING IN
CONTRACT, TORT OR OTHERWISE) ARISING OUT OF OR RELATING TO THIS AGREEMENT, THE OTHER LOAN DOCUMENTS OR THE TRANSACTIONS CONTEMPLATED HEREBY OR THEREBY. EACH PARTY HERETO HEREBY (A) CERTIFIES THAT NO REPRESENTATIVE, AGENT OR ATTORNEY OF ANY
OTHER PARTY HAS REPRESENTED, EXPRESSLY OR OTHERWISE, THAT SUCH OTHER PARTY WOULD NOT, IN THE EVENT OF LITIGATION, SEEK TO ENFORCE THE FOREGOING WAIVER, AND (B) ACKNOWLEDGES THAT IT AND THE OTHER PARTIES HERETO HAVE BEEN INDUCED TO ENTER INTO
THIS AGREEMENT BY, AMONG OTHER THINGS, THE MUTUAL WAIVERS AND CERTIFICATION IN THIS SECTION. 
 [signature page attached]

  
 -5-

 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be executed by
their respective officers thereunto duly authorized and delivered at Chicago, Illinois as of the date first above written. 

BORROWERS: 
  

									
	INFUSYSTEM HOLDINGS, INC.	 		 	FIRST BIOMEDICAL, INC.
					
	By:	 	 /s/ James M. Froisland
	 		 	By:	 	 /s/ James M. Froisland

	Name:	 	James Froisland	 		 	Name: 	 	James Froisland
	Title:	 	CFO	 		 	Title:	 	CFO
		
	INFUSYSTEM, INC.	 	
					
	By:	 	 /s/ James M. Froisland
	 		 		 	
	Name:	 	James Froisland	 		 		 	
	Title:	 	CFO	 		 		 	
				
	AGENTS AND LENDERS:	 		 		 	
				
	 BANK OF AMERICA, N.A., in its
 capacity as Administrative Agent,
	 		 		 	
					
	By:	 	 /s/ Rosanne Parsill
	 		 		 	
	Name:	 	 Rosanne Parsill
	 		 		 	
	Title:	 	 Vice President
	 		 		 	
				
	 BANK OF AMERICA, N.A., in its
 capacity as a Lender
	 		 		 	
					
	By:	 	 /s/ Sophia Love
	 		 		 	
	Name:	 	Sophia Love	 		 		 	
	Title:	 	Senior Vice President	 		 		 	
				
	KEYBANK NATIONAL ASSOCIATION, in its capacity as a Lender	 		 		 	
					
	By:	 	 /s/ Sukanya Raj
	 		 		 	
	Name: 	 	Sukanya Raj	 		 		 	
	Title:	 	Vice President	 		 		 	

  
 Waiver Agreement
Signature Page 

 GUARANTOR JOINDER 

The undersigned hereby joins in this Agreement, as of the date first above written, to acknowledge, consent and agree to the terms and
conditions thereof, including, without limitation, Sections 5.7 and 5.10 thereof, and to confirm that this Agreement shall not impair or otherwise affect its Obligations and grants of Liens under any of the Loan Documents to which it is a party.

  

			
	IFC LLC
		
	By:	 	/S/    SEAN MCDEVITT
	 Name:
	 	 Sean McDevitt

	Title:	 	 Chief Executive Officer

  
 Waiver
Agreement—Guarantor Joinder 

 Exhibit A 

Secretary’s Certificate 
 [see attached] 

 SECRETARY’S CERTIFICATE 

 

	To:	Bank of America, N.A., as administrative agent 

 This Certificate is being furnished pursuant to Section 4.1(b) of that certain Waiver Agreement (the “Agreement”), dated as of March 15, 2012 by and among INFUSYSTEM HOLDINGS, INC.,
a Delaware corporation (“Holdings”), INFUSYSTEM, INC., a California corporation (“InfuSystem”) and FIRST BIOMEDICAL, INC., a Kansas corporation (“FBI” and together with Holdings and InfuSystem, the
“Borrowers” and each individually a “Borrower”), BANK OF AMERICA, N.A. in its capacity as an Administrative Agent and as a Lender (“Agent”) and the other lenders party thereto (collectively,
together with Agent in its capacity as a Lender, the “Lenders”), which amends that certain Credit Agreement dated as of June 15, 2010 as amended by (i) that certain First Amendment to Credit Agreement dated as of
January 27, 2011, (ii) that certain Second Amendment to Credit Agreement dated as of April 1, 2011, (iii) that certain Third Amendment to Credit Agreement dated as of May 20, 2011 and (iv) that certain Fourth Amendment
to Credit Agreement dated as of July 21, 2011 (the “Credit Agreement”). Capitalized terms used but not defined herein shall have the meanings ascribed to such terms in the Agreement. 

The undersigned, Secretary of each Borrower, hereby certifies on behalf of such Borrower, that: 

1. Such Borrower has adopted resolutions sufficient to authorize the proper officers of such Borrower to execute and deliver the
Agreement in the name and on behalf of such Borrower, and each of them is authorized to cause such Borrower to borrow funds under the Credit Agreement. Such resolutions have not been rescinded or amended and are in full force and effect on and as of
the date hereof. 
 2. Other than the resolutions referred to in clause 1 above, there is no corporate action, consent or
governmental approval required for the execution, delivery and performance by such Borrower of the Amendment or any other document, instrument or agreement contemplated by the Amendment. 

[certificate continues on following page] 

 3. The following named persons were duly elected to, and are validly acting in, the offices
listed opposite each of their names and are authorized to execute on behalf of and in the name of each Borrower the Amendment and any and all other agreements, instruments or documents contemplated by the Amendment, and their respective signatures
set forth below are their genuine signatures. 
  

					
	 Name
	  	 Title
	  	 Signature

			
	 James Froisland
	  	Chief Financial Officer	  	/s/ James M. Froisland
			
	 Janet Skonieczny
	  	Secretary/Assistant Secretary1	  	/s/ Janet Skonieczny
			
	 Sean McDevitt
	  	Chief Executive Officer	  	/s/ Sean McDevitt

 4. I know of no proceeding for the dissolution or liquidation of any Borrower or threatening the
existence of any Borrower. 
 5. There have been no amendments to the Articles or Certificates of Incorporation or to the
By-laws of any Borrower since the date of the certified copies thereof provided to you in connection with the execution of the Credit Agreement. 
 6. Agent and the Lenders may rely on this Certificate until advised by a like certificate of any changes herein. 
 [signature page attached] 
  

	1 	Janet Skonieczny is the Secretary of Holdings, the Secretary of InfuSystem and the Assistant Secretary of FBI. 

 IN WITNESS WHEREOF, I have executed this Certificate on March 15, 2012. 

 

			
	 By:
	 	 /s/ Janet Skonieczny

	 Name:
	 	Janet Skonieczny
	 Title:
	 	Secretary/Assistant Secretary

 I, the undersigned, Chief Executive Officer of each Borrower, DO HEREBY CERTIFY that Janet
Skonieczny is the duly elected and qualified Secretary/Assistant Secretary of such Borrower, and the signature above is a genuine signature. 
 WITNESS my hand this 15th day of March, 2012. 
  

			
	 By:
	 	 /s/ Sean McDevitt

	 Name:
	 	Sean McDevitt
	 Title:
	 	Chief Executive OfficerGrant Agreement

 PORTIONS OF THIS EXHIBIT WERE OMITTED AND HAVE BEEN FILED SEPARATELY WITH THE SECRETARY OF THE COMMISSION
PURSUANT TO AN APPLICATION FOR CONFIDENTIAL TREATMENT UNDER RULE 406 OF THE SECURITIES ACT; [***] DENOTES OMISSIONS. 
  

Exhibit 10.1 

DOC-1695 

MICHIGAN STRATEGIC FUND 
 GRANT AGREEMENT WITH 
 MASCOMA CORPORATION 

The Michigan Strategic Fund (“MSF”) on December 2, 2008 enters into this agreement (the “Agreement”) with
Mascoma Corporation (“Grantee”). 
  

			
	Grantee:	  	Mascoma Corporation
		
	Federal I.D No:	  	203639247
		
	Telephone:	  	617-234-0099

 Recitals 
 On July 8, 2008, 2008 PA 175 amended the MSF Act, MCL 125.2001 et seq., to create the Centers of Energy Excellence (“COEE”) Program to promote development, acceleration and sustainability
of energy excellence sectors in the State of Michigan, MCL 125.2088q; 
 The MSF Board shall not expend more than $45,000,000 of
the money appropriated for the programs authorized under Chapter 8A from the 21st Century Jobs Trust Fund, MCL 125.2088 et seq., for the COEE Program; 
 The MSF may only award grants under the COEE Program to for-profit companies for one of the following purposes: (i) providing a match for foundation funding, federal funding, or international
investments of up to 50% of the total project costs; (ii) supplementing in-kind contributions provided by a person or entity other than this state; (iii) accelerating the commercialization of an innovative energy technology or process that
will be ready to market within 3 years of the effective date of the agreement; or (iv) activities of the COEE, including, but not limited to, workforce development and technology demonstration; 

Consistent with MCL 125.2088q, at its August 27, 2008 meeting, the MSF Board (i) approved the COEE award process as the
standard process for evaluating applications; (ii) approved an application for use by the prospective COEE for-profit companies (“Application”); (iii) appointed a committee to assist in the review process of applications
(“Committee”); and (iv) selected the MEDC as its centers manager to assist the MSF in the administration of the COEE Program; 
 On August 28, 2008, MEDC issued a press release announcing that the State is accepting applications for the COEE program; 

  
 1 

 PORTIONS OF THIS EXHIBIT WERE OMITTED AND HAVE BEEN FILED SEPARATELY WITH THE SECRETARY OF THE COMMISSION
PURSUANT TO AN APPLICATION FOR CONFIDENTIAL TREATMENT UNDER RULE 406 OF THE SECURITIES ACT; [***] DENOTES OMISSIONS. 
  

Grantee submitted an Application on September 5, 2008 via electronic mail to the MEDC and the Committee for consideration to receive
a grant under the COEE Program. 
 By Resolution dated September 24, 2008, upon recommendation of the Committee, the MSF
Board approved Grantee’s Application and offered Grantee a grant in the amount of $20,000,000 to be disbursed under the terms and conditions of this Agreement. 
 As used in this Agreement, the MSF and Grantee are individually a “Party” and, collectively, the “Parties.” 

 

	1.	NATURE OF ACTIVITIES: 

The Grantee will receive this grant to promote the development, acceleration, and sustainability of energy excellence sectors in Michigan,
in accordance with MCL 125.2088q (“Grant Activities”). 
  

	2.	PERFORMANCE SCHEDULE: 

The term of this Agreement shall begin on December 2, 2008 (the “Starting Date”) and end on December 31, 2013 (the
“Ending Date”), except as provided in Section 10. 
  

	3.	INCORPORATION BY REFERENCE: 

 The following documents are incorporated by reference as binding obligations, terms and conditions of the Agreement: 
 Attachment A: Grantee’s Budget 
 Attachment B: Grantee’s Milestones

 Attachment C: Grantee’s Application 
 Attachment D: United States Department of Energy Letter Dated September 23, 2008 
 In the event of any inconsistency between the provisions of Attachments A, B or C and this Agreement, the provisions of this Agreement shall control. 

 

	4.	GRANT PAYMENT SCHEDULE INFORMATION: 

  

	 	A.	Payments. The MSF agrees to provide the Grantee a grant in an amount not to exceed $20,000,000 (“Grant Funds”). Not more than 15% of the Grant Funds
can be used for administrative costs or overhead by the Grantee or for administrative costs or overhead by any subcontractor hired to implement any portion of this Agreement. All payments of Grant Funds are subject to the availability of
funds. 

 An initial payment in the amount of $12,100,000 (which shall include $2,000,000 for the Center of
Energy Excellence) shall be made within 30 calendar days of completion of the Initial Milestone referenced in Attachment B, if the Grantee has 

  
 2 

 PORTIONS OF THIS EXHIBIT WERE OMITTED AND HAVE BEEN FILED SEPARATELY WITH THE SECRETARY OF THE COMMISSION
PURSUANT TO AN APPLICATION FOR CONFIDENTIAL TREATMENT UNDER RULE 406 OF THE SECURITIES ACT; [***] DENOTES OMISSIONS. 
  

verified that the information in the State of Michigan (the “State”) Vendor ID system is sufficient to authorize the disbursement of funds. The Grantee’s performance of the Grant
Activities shall be reflected in a Semi-Annual Progress Report (as required by Section 6C), and any such other information obtained by the MSF, and, if found by the Grant Administrator (defined in Section 5) to evidence that the Grantee is
in material compliance with the requirements of this Agreement and the scope of work spelled out in Attachments A, Budget Period One Milestones in Attachment B, and C, the second payment of $7,900,000.00 will be made to the Grantee for the purpose
of achieving Budget Period Two Milestones as referenced in Attachment B. All subsequent payments, if any, will be disbursed upon receipt and approval by the Grant Administrator of the Grantee’s progress as described in the milestones listed in
Attachment B. The final payment, if any, will be made upon receipt and approval by the Grant Administrator of the Final Progress Report demonstrating achievement of milestones and material compliance with Attachments A, B, and C. The expenditure of
state funds shall be reported by line item and compared to the approved budget. 
 MSF’s obligation to disburse any portion
of the Grant shall be suspended upon the occurrence, and during the continuance of an Event of Default (as defined in Section 10). Any changes to the amount of Grant Funds disbursed must receive prior written approval from the Grant
Administrator and the MSF. 
  

	 	B.	Grantee’s Budget. All Grant Funds will be spent in the manner set forth in the Grantee’s Budget (Attachment A). The Grantee may reallocate expenditures
between categories within the Grantee’s Budget of up to ten percent (10%) of total Grant Funds without prior approval of the Grant Administrator. Grant Funds may not be used to pay employees or contractors who perform services outside the
State without the prior written approval by the Grant Administrator and the MSF, unless identified in an approved budget. This Agreement does not commit the MSF to approve requests for additional funds during or beyond the term of this Agreement.

  

	5.	GRANT ADMINISTRATOR: 

 The
Michigan Economic Development Corporation (“MEDC”) is providing administrative services to the MSF for this Grant. The Grantee should communicate with the following MEDC representative regarding this Grant: 

Martin Dober 

Michigan Economic Development Corporation 
 300 N. Washington Square 
 Lansing, Michigan 48913 

Telephone: (517)335-6438 
 Fax: (517)241-8797 

  
 3 

 PORTIONS OF THIS EXHIBIT WERE OMITTED AND HAVE BEEN FILED SEPARATELY WITH THE SECRETARY OF THE COMMISSION
PURSUANT TO AN APPLICATION FOR CONFIDENTIAL TREATMENT UNDER RULE 406 OF THE SECURITIES ACT; [***] DENOTES OMISSIONS. 
  

 

	6.	GRANTEE DUTIES: 

 The
Grantee agrees to: 
  

	 	A.	Undertake and complete the activities as described in the Grantee’s Milestones and its Application (Attachments B and C). 

 

	 	B.	Provide access to its facilities for the MSF and MEDC, Auditor General and their respective personnel upon reasonable notice and during normal working hours. Grantee
acknowledges that the MSF or its designee anticipates undertaking, at a minimum, an annual site visit at approximately the annual anniversary date of the Agreement. Grantee shall cooperate with the chief compliance officer, if contacted, as provided
in MCL 125.2088i(6)(h). 

  

	 	C.	Provide to the Grant Administrator semi-annual summary progress reports (the “Semi-Annual Progress Reports”) due on each May 1 and November 1 for
the six month period ending a full month prior to the due date and a final progress report (the “Final Progress Report”)(collectively the “Reports”). The Semi-Annual Progress Reports shall include a description of the milestones
achieved during that reporting period, budget, metrics, statistics, intellectual property, commercialization status and any supporting documentation or any other information or data reasonably requested by the Grant Administrator to assess
compliance with the Grantee’s Budget (Attachment A) and Milestones (Attachment B). 

 Within three
(3) months following the completion of the last milestone, the Grantee shall provide the MSF and Grant Administrator with a Final Progress Report. The Final Progress Report shall be a comprehensive report that shall include sufficient
information to establish that the milestones identified in Attachment B have been achieved during the grant period and that Grantee has complied with the Grantee’s Budget (Attachment A). The Final Progress Report shall include any other
information or data requested by the Grant Administrator needed to assess overall compliance with Grantee’s Budget (Attachment A) and Milestones (Attachment B). The’ Reports shall be in a form as approved in advance by the Grant
Administrator. Reprints of publications published pursuant to this award are to be included in the Semi-Annual Progress Reports and the Final Progress Report pursuant to Section 13. The Grantee shall provide immediate notice to the MSF and the
Grant Administrator of any material change to activities funded with the Grant, including, but not limited to, changes to key personnel. All material changes to milestones and increases in budget (other than as provided in Section 4B above)
must be pre-approved in writing by the Grant Administrator and the MSF. 
  

	 	D.	 Comply with the MSF Act, MCL 125.2001 et seq., as amended, including, but not limited to, MCL 125.2088q(5), all laws, ordinances, regulations, rules,
orders, judgments, decrees or other requirements imposed by any governmental authority 

  
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to which it is subject, including those related to research misconduct and research integrity during the term of this Agreement and will provide immediate notice to the MSF of any alleged or
proven violation. In addition, the Grantee shall obtain any licenses, permits or other governmental authorization necessary to carry out its duties under the Agreement. 

 

	 	E.	Provide the MSF all information necessary for the MSF to produce reports required by MCL 125.2088n. 

 

	7.	RELATIONSHIP OF THE PARTIES: 

 Neither the Grantee, nor any employee or agent of Grantee is currently, or in the future will be, an employee or agent of the MSF or MEDC as a result of this Agreement. The MSF is not responsible for any
insurance or other fringe benefits, including, but not limited to, social security, workers’ compensation, income tax withholdings, retirement or leave benefits, for the Grantee or its employees. The Grantee assumes full responsibility for all
costs and expenses associated with its performance under this Agreement including, but not limited to, the provision of all insurance coverage and fringe benefits for its employees, all tools, supplies, materials, equipment and office space. The
Grantee shall retain all control of its employees and staffing decisions, independent of the direction and control of the MSF and the MEDC. 
  

	8.	PUBLICITY: 

 Any
publicity, advertising or news releases regarding this Agreement shall only contain the information, material or data mutually approved in writing by the Parties. 
  

	9.	ACCESS TO RECORDS AND CONFIDENTIALITY: 

 The Grantee shall maintain reasonable books and records, including evidence that the duties as set forth in this Agreement actually were performed, and the identity of all individual persons, firms and
entities paid for such duties, and shall allow access and inspection of those books and records including financial records and all other information and data relevant to this Agreement (including information or data deemed by the Grantee as
confidential information) to the Grant Administrator, any employee of the MSF, the MEDC, and the auditor general of the State of Michigan. Those records shall be retained for a minimum period of 3 years beyond termination of this grant, or such
length of time as required under applicable state or federal law. The Grantee shall adhere to the Generally Accepted Accounting Principles and shall maintain records which will allow for the comparison of actual outlays with budgeted amounts. The
Grantee’s overall financial management system must ensure effective control over and accountability for all funds received. Accounting records must be supported by source documentation such as time sheets and invoices. The MSF and MEDC shall be
allowed to disclose confidential information only to the extent required by applicable law (including, without limitation, the Freedom of Information Act). The MSF and MEDC shall maintain the confidentiality of all Grantee’s confidential
information acknowledged 

  
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as confidential by-the MSF Board pursuant to the MSF Act. However, neither the MSF nor MEDC shall be liable for any inadvertent disclosure of any of the Grantee’s confidential information.

  

	10.	TERMINATION OR CANCELLATION: 

  

	 	A.	The MSF may terminate this Agreement by providing written notice of default and termination to the Grantee (“Notice of Default and Intent to Terminate”) upon
the occurrence of any of the following events or conditions (“Event of Default”): 

  

	 	(i)	any representation made by the Grantee is determined by the MSF, in its reasonable judgment, to be incorrect in any material respect at the time that such
representation was made; 

  

	 	(ii)	the Grantee’s, or any qualified entity that is party to the Agreement, failure to comply with any of the terms and conditions of this Agreement;

  

	 	(iii)	the Grantee’s dissolution of the center of energy excellence and disposition of any assets; and 

 

	 	(iv)	expenditure of the Grant for purposes other than as set forth in this Agreement. 

 The Notice of Default and Intent to Terminate shall provide the Grantee a period of at least forty-five (45) calendar days to cure the Event of Default. If the Event of Default remains uncured
following the forty-five (45) calendar-day period, the MSF shall provide Final Notice of Termination (“Final Notice”), which shall be effective as of the date of the Final Notice. 

 

	 	B.	Grantee acknowledges that MSF’s performance of its payment obligation is dependent upon the continued receipt of government funding. In the event that the State
Legislature or any State official, commission, authority, body, or employee, or the federal government (a) takes any legislative or administrative action, which fails to provide, terminates or reduces the funding necessary for this Grant, or
(b) takes any legislative or administrative action, which is unrelated to the source of funding for this Grant, but which affects the MSF’s ability to fund and administer this Grant, and other MSF programs, then the MSF may cancel this
Agreement by providing notice to the Grantee of cancellation. Cancellation may be made effective immediately, upon delivery of notice to the Grantee, or within such other time period as the MSF, in its sole discretion, deems reasonable.

  

	 	C.	 In the event of a termination, the MSF shall have no further obligation to make a Grant payment. The Grantee shall, unless otherwise directed by the
MSF in writing, immediately take all reasonable steps to terminate operations under this Agreement, and to avoid or minimize further expenditures under this Agreement. The Grantee shall reimburse the MSF for disbursements of the Grant determined

  
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to have been expended for purposes other than those in the Grantee’s Budget, and for the Grant Funds which was previously disbursed, but not yet expended by the Grantee, and which are not
subject to an irrevocable or non-cancelable commitment. 

  

	 	D.	In accordance with 2005 PA 215, in particular MCL 125.2088n, if the MSF Board has a reasonable belief that a breach of this Agreement has occurred, the MSF has the
right to have the Grantee’s financial statements separately audited by an independent certified public accountant at its sole cost and expense. If the audit reveals that a breach of this Agreement has occurred, the Grantee shall reimburse the
MSF for the fees and expenses incurred to perform the audit. 

  

	11.	MEDC EMPLOYEES: 

 The
Grantee will not hire any employee of the MEDC to perform any duties covered by this Agreement without prior written approval from the MSF and the CEO of the MEDC. 
  

	12.	CONFIDENTIAL INFORMATION: 

The Grantee and its employees, agents, or representatives shall not release, other than to the extent compelled by law, any information or
data, including but not limited to targeted business lists, economic development analyses, computer programs, or databases furnished to the Grantee by the MSF or MEDC (collectively “Confidential Information”) without the written consent of
the MSF or MEDC, as appropriate. Confidential Information does not include information that is already in the possession of, or is independently developed by, Grantee; becomes publicly available other than through breach of this Section; or is
received by Grantee from a third party with authorization to make such disclosures or is released with the appropriate prior written consent of the MSF or MEDC. 
  

	13.	PUBLICATIONS: 

 Except for
Confidential Information described in Section 12, the MSF agrees that Grantee may authorize, in its discretion, any person performing work funded under this Agreement shall be permitted to present at symposia, national, or regional professional
meetings, and to publish in journals, theses or dissertations, or otherwise of their own choosing, methods and results of their research. Grantee shall, at its sole discretion and at its sole cost and expense, prior to publication, seek intellectual
property protection for any Inventions (as defined in Section 14) if commercially warranted. Grantee shall submit to the MSF and Grant Administrator a reprint of all articles that Grantee has published resulting from work performed hereunder
with the Semi-Annual Progress Report as required under Section 6. Grantee shall acknowledge the work was supported by Grant #1695 of the 21st Century Jobs Trust Fund received through the MSF Board from the State of Michigan, as appropriate, in
any such publication. 

  
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	14.	INTELLECTUAL PROPERTY RIGHTS: 

 The Grantee shall retain ownership to the entire right, title, and interest in all results and data arising from Grantee’s activities under this Agreement and in any new inventions, improvements, or
discoveries developed or produced by the Grantee under this Agreement, including, but not limited to, concepts, know-how, software, materials, methods, and devices (“Inventions”) and shall have the right to enter into license agreements
covering Inventions. 
  

	15.	CONFLICT OF INTEREST: 

The Grantee affirms that there exists no actual or potential conflict of interest between the Grantee, the Grantee’s key personnel or
its family, business, or financial interest (“Grantee’s Interests”) and the activity under this Grant. The Grantee affirms that it has a procedure in place to require disclosure and subsequent management of conflicts of interest
between the Grantee’s key personnel, its family’s, or business’s financial interests and its research activities under the Grant. In the event of a change in either its private interests or activities under this Grant, Grantee will
inform the MSF immediately in writing regarding possible conflicts of interest that may arise as a result of such change. 
  

	16.	INDEMNIFICATION AND GRANTEE LIABILITY INSURANCE: 

 To the extent allowed by law, the Grantee shall indemnify, defend and hold harmless the MSF and the MEDC, including their respective participants, committee members, officers, agents and employees, from
any damages that it may sustain through the negligence or willful misconduct of the Grantee pertaining to the performance of this Agreement. The Grantee shall maintain such insurance as necessary to comply with this provision. The Grantee will
provide and maintain its own public liability, property damage, and workers’ compensation insurance. The insurance shall be written for not less than any limits of liability required by law for the Grantee’s obligation of indemnification
under this Agreement. 
  

	17.	TOTAL AGREEMENT: 

 This
document, together with all Attachments, contains the entire agreement between the Parties, superseding any prior or concurrent agreements with respect to the subject matter, and supersedes all prior agreements, understandings and communications, of
any nature with respect to the subject matter, and no oral or written terms or conditions which are not contained in this Agreement shall be binding upon the Parties. This Agreement may not be amended except by written agreement executed by the
Parties. 
  

	18.	ASSIGNMENT/TRANSFER/SUB GRANTING: 

 The Grantee shall not assign, transfer, convey, sub-contract, sub-grant or otherwise dispose of any duties or rights under this Agreement, without the prior written approval of the MSF. The terms and
conditions of this Agreement shall be binding upon and inure to 

  
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the benefit of the Parties and their respective successor(s) and permitted assign(s). For the avoidance of doubt, the patties agree that a change in the equity ownership of Grantee or use of
Grant proceeds as a capital contribution to a joint venture with J. M. Longyear shall not constitute an assignment, transfer, conveyance, sub-contract, or sub-grant of the duties and rights under this Agreement. 

 

	19.	NON-DISCRIMINATION AND UNFAIR LABOR PRACTICES: 

 In connection with this Agreement, the Grantee agrees not to discriminate against any employee or applicant for employment, with respect to their hire, tenure, terms, conditions or privileges of
employment, or any matter directly or indirectly related to employment, because of race, color, religion, national origin, ancestry, age, sex, height, weight, marital status, physical or mental disability unrelated to the individual’s ability
to perform the duties of the particular job or position. The Grantee further agrees that every subcontract entered into for performance of this grant will contain a provision requiring nondiscrimination in employment, as specified in this Agreement,
binding upon each subcontractor. This covenant is required pursuant to the Elliot Larsen Civil Rights Act, 1976 PA 453, MCL 37.2101, et seq., and the Persons with Disabilities Civil Rights Act, 1976 PA 220, MCL 37.1101, et seq., and
any breach thereof may be regarded as a material breach of this Agreement. In addition, consistent with Executive Directive 2007-24, the Grantee agrees not to discriminate against any employee or applicant for employment, with respect to their hire,
tenure, terms, conditions or privileges of employment, or any matter directly or indirectly related to employment because of sexual orientation unrelated to the individual’s ability to perform the duties of the particular job or position.

 Pursuant to 1980 PA 278, MCL 423.321, et seq., the State shall not award a grant or subcontract to an employer whose
name appears in the current register of employers failing to correct an unfair labor practice compiled pursuant to Section 2 of the Act. The United States Labor Relations Board compiles this information. The Grantee shall not enter into a
contract with a subcontractor, manufacturer, or supplier whose name appears in this register. Pursuant to Section 4 of 1980 PA 278, MCL 423.324, the State may void any contract if, subsequent to the award of the contract, the name of the
Grantee as an employer, or the name of a subcontractor, manufacturer, or supplier of the Grantee appears in the register. 
  

	20.	TRADE SECRETS ACT: 

 The
MSF claims the additional protection for misappropriation of trade secrets, which include targeted business lists, economic development analyses, computer programs and databases under the Michigan Uniform Trade Secrets Act, 1998 PA 448, MCL
445.1901 et seq. The MSF retains its rights under this Act to actual loss and unjust enrichment caused by the misappropriation. The MSF further retains the right to enjoin any disclosure of trade secrets or other breach of the use of
confidential information, at any time, and retains all legal and equitable remedies. 

  
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	21.	PREVAILING WAGE: 

 If the
activities funded by this Grant involve construction of a building or of facilities, the Grantee, its sub-grantees and sub-contractors shall comply with prevailing wage and fringe benefit rates for the same or similar work in the locality in which
the work is to be performed. 
  

	22.	FRINGE BENEFITS: 

 Grantee
understands that neither Grantee nor Grantee’s employees or contract personnel are eligible to participate in any employee pension, health, vacation pay, sick pay, or other fringe benefit plan of the MSF or MEDC. 

 

	23.	WORKERS’ COMPENSATION: 

 The MSF or MEDC shall not obtain workers’ compensation insurance on behalf of Grantee or Grantee’s employees. If Grantee hires employees to perform any work under this Agreement, Grantee shall
cover them with workers’ compensation insurance and shall maintain such insurance during the term of this Agreement. The MSF or MEDC may, in its discretion, require Grantee to provide evidence of such coverage. 

 

	24.	UNEMPLOYMENT COMPENSATION: 

The MSF or MEDC shall make no state or federal unemployment compensation payments on behalf of Grantee or Grantee’s employees or
Grantee personnel. Grantee will not be entitled to these benefits in connection with work performed under this Agreement. If Grantee files a petition for and receives unemployment compensation, the total amount of unemployment compensation awarded
to and received by Grantee shall be deducted from and be an offset against the amount of compensation due and payable to Grantee by the MSF under this Agreement. 
  

	25.	GOVERNING LAW: 

 This
Agreement shall be governed by, and construed in accordance with, the laws of the State of Michigan. The terms of this provision shall survive the termination of this Agreement. 

 

	26.	WAIVER: 

 A failure or
delay by the MSF in exercising any right with respect to this Agreement will not be presumed to operate as a waiver unless otherwise stated in this Agreement, and a single or partial exercise of any right will not be presumed to preclude any later
or further exercise of that right, or the exercise of any other right. 

  
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	27.	AVAILABLE REMEDIES: 

 The
termination of this Agreement by the MSF is not intended to be the sole and exclusive remedy, and shall be cumulative and in addition to every other provision or remedy given in this Agreement or now or hereafter existing at law, in equity, by
statute or otherwise. 
  

	28.	FURTHER ACTS: 

 The
Parties agree to perform any further acts to execute and deliver any further documents, which may be reasonably necessary to carry out this Agreement. 
  

	29.	NOTICES: 

 Any notice,
approval, request, direction or other communication under this Agreement shall be given in writing and shall be deemed to have been delivered and given for all purposes: (i) on the delivery date, if delivered by electronic mail or by confirmed
facsimile; (ii) on the delivery date, if delivered personally to the Party to whom it is directed; (iii) one (1) business day after deposit with a commercial overnight carrier, with written verification of receipt; or (iv) three
(3) business days after the mailing date, whether or not actually received, if sent by United States mail, return receipt requested, postage and charges prepaid, or. any other means of rapid mail delivery for which a receipt is available. The
notice address for the Parties shall be the address set forth below, with the other relevant notice information, including the recipient for notice and, as applicable, such recipient’s fax number or e-mail address, to be as reasonably
identified by notifying Party. The MSF and the Grantee may, by notice to the other party, designate any further or different addresses or parties to send subsequent notices. 
 Bruce A. Jamerson 
 Chief Executive Officer 

Mascoma Corporation 
 1380 Soldiers Field Road 
 Boston, MA 02135 

with a copy to: 

Jim Schumacher 

Senior Vice President, Corporate Development 
 Mascoma Corporation 
 1380 Soldiers Field Road 

Boston, MA 02135 

and 
 Ronald E.
Hodess 
 Miller Canfield 
 840 West Long Lake Road 
 Troy, Michigan 48098 

  
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and 
 Michigan
Strategic Fund 
 Martin Dober, Vice President, New Markets 

300 North Washington Square 
 Lansing, Michigan 48913 
  

	30.	AUTHORITY TO EXECUTE THIS AGREEMENT: 

 The signatories below warrant that they are empowered to enter into this Agreement on behalf of their respective Party. 
  

	31.	SEVERABILITY: 

 The
invalidity or unenforceability of a particular provision of this Agreement shall not affect the validity or enforceability of any other provision of this Agreement, provided that the principal intent of this Agreement can be preserved. 

[Signatures appear on the following page.] 

  
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	MASCOMA CORPORATION
		
	By:	 	 /s/ Bruce A. Jamerson

		
		 	Bruce A. Jamerson

			
	
	Its: Chief Executive Officer
		
	Date:	 	 12/1/08

			
	
	MICHIGAN STRATEGIC FUND
		
	By:	 	 /s/ Cindy Douglas

		
		 	Cindy Douglas

			
	
	Its: Fund Manager
		
	Date:	 	 12/2/08

  
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ATTACHMENT A 

GRANTEE’S BUDGET 
  

					
	 Budget Period 1
	  	$
Million	 
		
	 Environmental Permitting
	  	 	1.5	  
	 Ethanol Facility Preliminary Engineering
	  	 	3.0	  
	 Ethanol Facility Cost Estimating
	  	 	0.3	  
	 Team Build
	  	 	1.5	  
	 Commercial agreements
	  	 	0.5	  
	 Project Finance
	  	 	1.3	  
	 Infrastructure and Utility Preliminary Engineering
	  	 	1.5	  
	 Infrastructure and Utility Cost Estimating
	  	 	0.5	  
	 COEE University Research
	  	 	2.0	  
		  	  
	  
	 
	 Total Budget Period 1
	  	 	12.1	  
		
	 Budget Period 2
	  	 	 
		
	 Detailed Engineering for Ethanol Facility
	  	 	5.0	  
	 Construction
	  	 	2.9	  
		  	  
	  
	 
	 Total Budget Period 2
	  	 	7.9	  
		
		  	  
	  
	 
	 Grand Total, Budget Periods 1 and 2
	  	 	20.0	  
		  	  
	  
	 

  
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ATTACHMENT B 

GRANTEE’S MILESTONES 

Initial Milestones 
  

	 	1.	Provide Notice of Financial Assistance and Acquisition for Budget Period One issued by the United States Department of Energy in connection with Grant Number
DE-FC36-08GO18103 as referenced in the letter issued by United States Department of Energy incorporated as Attachment D hereto. 

  

	 	2.	Provide documentation of Baisch Engineering office in Michigan and ability to conduct business in Michigan. 

Budget Period One Milestones 
  

	 	1.	File all required environmental and permitting applications. 

  

	 	2.	Complete preliminary design engineering of cellulosic ethanol facility including process flow diagrams and preliminary cost estimates. 

 

	 	3.	Complete preliminary design engineering for infrastructure including engineering drawings and preliminary cost estimates. 

 

	 	4.	Complete site acquisition. 

  

	 	5.	Finalize commercial agreements including fiber supply, construction & operation of the facility, and off-take agreements. 

 

	 	6.	Complete project finance package to be offered to potential funding sources. 

 

	 	7.	Collaborate on commercialization and technology transfer opportunities with the execution of university agreements for the COEE. 

 

	 	8.	Develop governance structure for COEE including plan for dissolution of COEE and disposition of COEE assets. 

 

	 	9.	Provide Notice of Financial Assistance and Acquisition from United States Department of Energy for Budget Period Two under Grant Number DE-FC36-08GO18103.

 Budget Period Two Milestones 
  

	 	1.	Complete detailed design engineering of cellulosic ethanol facility including process flow diagrams and detailed cost estimates. 

 

	 	2.	Complete detailed design engineering for infrastructure including engineering drawings and detailed cost estimates. 

 

	 	3.	Provide final report on university research conducted under the COEE. 

  

	 	4.	Complete capital raise for construction of cellulosic ethanol facility. 

  

	 	5.	Locate and retain commercialization opportunities evidenced by ground-breaking of cellulosic ethanol facility. 

  
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ATTACHMENT C 

GRANTEE’S APPLICATION 

  
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 August 20, 2008 
 Mr. Martin Dober 
 Vice President 
 Michigan Economic Development Corporation 
 300 N. Washington Sq. 

Lansing, MI 48913 
 Dear Mr. Dober,

 Please accept this letter as Mascoma Corporation’s formal request for grant funding under the newly established Center of Energy
Excellence Program. Mascoma Corporation will serve as the lead private sector company under the grant and will work together with JM Longyear Company of Marquette, MI and university partners Michigan State University and Michigan Technological
University and other MI based businesses as outlined in the attached summary business plan. 
 The total amount of the program support
requested, meant to be consistent with MEDC’s commitment letter dated August 29th is as follows: 
  

	 	•	 	 $20MM in project development funding as a targeted industry incentive to be disbursed over two years (of which $2MM will be segregated out in the first
year to fund supply chain optimization work to be undertaken through the Center of Energy Excellence program already established with university partners) 

 

	 	•	 	 $3.5MM in site based funding to improve infrastructure (rail, road and utilities) 

 

	 	•	 	 Assistance in working with appropriate State Agencies in developing innovative long-term fiber supply agreements to support the Frontier project’s
commercial scale cellulosic ethanol facility and potentially other co-located operations 

  

	 	•	 	 Additional assistance in establishing a tax-free renaissance zone in the community where the plant will be situated, designation of Mascoma as an
anchor company eligible for MTB tax credits subject to attracting co-located businesses, assistance in obtaining potential tax exempt private activity financing, assistance with job training and regulatory permitting 

  
  

1380 Soldiers Field Road, Boston, Massachusetts 02135    + Tel: 617.234.0099    + Fax:
617.888.0408 
 www.mascoma.com 

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 As evidence of our commitment to commercialize Mascoma technology in Michigan, the funds and assistance
above will be matched by $8MM from Mascoma, a commercial site location valued at approximately $1MM contributed by project partner JM Longyear and up to $26MM in grant funding Mascoma has been selected to receive under a grant from the U.S.
Department of Energy competitively awarded to Mascoma for the construction of a cellulosic ethanol facility. 
 Mascoma Technology

 In the current economic and political climate, there has been enormous attention focused on the need to develop sustainable and renewable
sources of transportation fuel. As an alternative to petroleum based fuels, ethanol has a significant and growing role in this development by providing a cleaner, domestically-produced, renewable energy solution. The current generation of ethanol
production in the U.S. however, utilizes corn and other edible feedstocks now widely viewed as offering only a partial solution to US renewable fuels objectives. As a complimentary alternative Mascoma is committed to developing sustainable,
economically viable, next generation ethanol from cellulosic (non-food) feedstocks such as wood, grasses and other energy crops. Additionally, producing ethanol from cellulosic biomass minimizes the environmental impact of corn based fuel ethanol
production through a more energy efficient process with lower greenhouse gas emissions. Mascoma’s proprietary approach utilizes biotechnology tools to convert cellulosic materials to ethanol and other end products. Mascoma is developing
proprietary organisms and processes designed to: 
  

	 	•	 	 Rapidly break down the components of biomass 

  

	 	•	 	 Convert a range of sugars and polymers of sugars to ethanol 

 

	 	•	 	 Thrive in a manufacturing environment 

 Mascoma’s research laboratories are now developing a new generation of the best cellulose-utilizing and ethanol-fermenting microbes, simplifying the process and allowing nature to do most of the work. Mascoma Corporation has the
world’s largest research team focused on the commercial development of Consolidated Bio-Processing or CBP. 
 University Collaboration

 Developing creative approaches to ensure sustainable forest products and feedstock strategies is essential to the commercial scale
production of cellulosic 

  
  

1380 Soldiers Field Road, Boston, Massachusetts 02135    + Tel: 617.234.0099    + Fax:
617.868.0408 
 www.mascoma.com 

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ethanol in the State of Michigan. Michigan State University and Michigan Technological University have worked closely with Mascoma over the last year to identify alternative paths for the
commercialization of cellulosic ethanol in the State and highly value this expanding partnership. More specifically, efforts encompassed by this proposed project emphasize feedstock supply chain optimization elements that are absolutely necessary to
move the industry forward from theory to practice. Mascoma, MEDC and the Universities have formed The Feedstock Supply Chain Center of Energy Excellence to promote the development, acceleration, and sustainability of woody biomass feedstocks,
including, production, availability, supply, procurement, harvest, processing, transportation, and delivery to the facility. It will develop technologies, tools and outreach that quantify and increase feedstock supply, facilitate business decisions
and promote cost effective, low greenhouse gas supply chain solutions. 
 Summary Project Benefits 

Mascoma’s Michigan project will deliver on the State’s renewable energy objectives by commercializing state of the art cellulosic ethanol
production technology for low cost liquid transportation fuels and other co-products for use in the State. The process requires 20% of the energy and 5% of the carbon footprint of that required to produce an equivalent gallon of petroleum fuel.
Working with the Michigan based forest products industry to utilize available fiber under certified practices (growth levels exceed harvest levels) from Michigan forests will support sustainable forestry goals as well as create new incremental jobs.
In addition, the potential use of emerging energy crops, such as switchgrass and plantation poplar/willow, offer economic development opportunities by optimizing marginal agricultural lands in the region around the facility. University and other
Center of Energy Excellence collaborations will benefit from both research funding arid access to first of its kind project lifecycle data for use in validating the field. Mascoma’s investment in Michigan has also attracted approximately $26MM
of matching funds for the project from the US Department of Energy. Finally, the commercial scale production facility represents and investment of over $200MM in Michigan and is expected to create over 50 direct and 300 indirect jobs. 

In closing Martin, we would like to thank you for your willingness to consider Mascoma Corporation’s request for funding under this innovative
program. All of us here at Mascoma look forward to working with the MEDC and other Michigan based partners to ensure this project’s success. 

  
  

1380 Soldiers Field Road, Boston, Massachusetts 02135    + Tel: 617.234.0099    + Fax:
617.868.0408 
 www.mascoma.com 

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	Sincerely,
	
	/s/ Jay Niles
	 Jay Niles
 Vice President,
Business Development
 Mascoma Corporation

  
  

1380 Soldiers Field Road, Boston, Massachusetts 02135    + Tel: 617.234.0099    + Fax:
617.868.0408 
 www.mascoma.com 

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PURSUANT TO AN APPLICATION FOR CONFIDENTIAL TREATMENT UNDER RULE 406 OF THE SECURITIES ACT; [***] DENOTES OMISSIONS. 
  

			
		  	 

		  	  
 August 26, 2008

 
 Mr. Martin Dober
 Vice President
 Michigan Economic Development Corporation

300 N. Washington Square
 Lansing, MI
48913

	 

  
 OFFICE OF

BIO-BASED

TECHNOLOGIES
  

Steven G. Pueppké
 Director
  
 Michigan State University
 109 Agriculture Hall

East Lansing, Michigan

48824-1039
 (517)
353-9607
 FAX: (517) 353-5406
 E-Mail: pueppke@msu.edu
	  	  
 Dear Mr. Dober,

 
 Michigan State University looks forward to the opportunity to participate as an
anchor university partner in the recently formed Center of Energy Excellence Program established in conjunction with MEDC’s renewable energy efforts. The total amount of research to be funded through Mascoma’s participation in the Center
of Energy Excellence for this project will be $2M.
  
 Developing creative
approaches to ensure sustainable forest products and feedstock strategies is essential to the commercial scale production of cellulosic ethanol in the State of Michigan. Michigan State University has worked closely with Mascoma over the last year to
identify alternative paths for the commercialization of cellulosic ethanol in the State and highly values this expanding partnership. More specifically, efforts encompassed by this proposed project emphasize feedstock supply chain optimization
elements that are absolutely necessary to move the industry forward from theory to practice.
  
 The Feedstock Supply Chain Center of Energy Excellence will promote the development, acceleration, and sustainability of woody biomass feedstocks, including issues relating to the production,
availability, supply, procurement, harvest, processing, transportation, and delivery of the feedstocks to the cellulosic ethanol facility. It will also develop technologies, tools and outreach that quantify and increase feedstock supply, facilitate
business decisions and promote cost effective; low greenhouse gas supply chain solutions.
  
 Feedstock/Raw Material Supply
  
 The Center of Energy Excellence will document the current inventory, availability and supply, identify barriers and mechanisms to increase availability and supply, and help develop mutually beneficial
feedstock sourcing scenarios for both the feedstock owner and the feedstock user. Areas that may be examined include, but are not limited to, current standing growing stock, silviculture, management and productivity, feedstock availability, short
rotation woody crop development, current policies and landowner perceptions, potential feedstock/fiber agreements, mechanisms for certifying sustainability, life cycle analyses for low greenhouse gas solutions, and landowner and public
outreach.

		
	 MSU is an alternative-action,
 equal-opportunity Institution.
	  	

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		  	 Mr. Martin Dober

August 26, 2008
 Page 2

		  	  
 Supply Chain Optimization

 
 One of the primary objectives of the Center’s collaborative efforts is to
promote a cost-effective delivered final product by focusing on the supply chain components of short-rotation woody crop establishment, harvest/processing, transportation and eventual delivery to the gate. The university teams will interface with
the manufacturing process and existing feedstock users to identify opportunities to improve overall supply chain efficiencies and synergies. Areas to be examined may include, but are not limited to, analyzing the cost/efficiencies of short-rotation
woody crops, harvest, pretreatment and transportation systems. In addition, the Center intends to analyze the cost trade-offs between vertical integration of harvest and transportation technologies with the manufacturing and product distribution
processes vs. the current customary nonintegrated model, life cycle analyses for low greenhouse gas solutions, outreach and training.
  

Workforce Talent/Training
  

Finally, workforce talent and training spans all activities of feedstock supply chain and will have to be addressed by the Center of Energy Excellence
project. Specific training and workforce talent recruitment opportunities will be identified that will support an optimized supply chain of feedstocks, with an emphasis on feedstock production through delivery to the gate and optimization
opportunities identified as part of the interface with the manufacturing process and distribution of the final product.
  
 In summary, Michigan State University enthusiastically supports its participation in the Center of Energy Excellence Program and looks forward to advancing the objectives of the MEDC on behalf of the
Mascoma project. Thank you in advance for your consideration of this proposal.

		
		  	 Sincerely,
  

/s/ Steven G. Pueppke
 Steven Pueppke

Director, Office of Biobased Technologies
 MSU
Assistant Vice President for Research and Graduate Studies
 Director, Michigan Agricultural Experiment Station

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 Mascoma Corporation and JM Longyear LLC 

(“Frontier Renewable Resource Company, LLC”) 
 BUSINESS PLAN 
 August 2008 

Commercial scale deployment of cellulosic ethanol technology integrated with biomass power and timber businesses - combining step
change technology with complimentary wood fiber businesses to create a sustainable cost advantage and a new business model for long term value creation in Michigan. 
 As provided in the Michigan Strategic Fund Act (“MSF Act”), Mascoma requests that “financial and proprietary information,” as defined in the MSF Act, contained within this proposal
submission be protected from disclosure under the Michigan FOIA. Such information IS indentified directly within the material submitted by Mascoma and complies with the following requirements: 

 

	 	1.	Each component and portion of the narrative identified for confidential treatment is marked in bolded text and marked with asterisks and brackets (*[bold
if text]*) within the narrative. 

  

	 	2.	Each attachment and the portion of the document identified for confidential treatment is marked in bolded text and marked with asterisks and brackets
(*[bold if text]*) on the attachment.  

  

	 	3.	Mascoma lists the following pages containing portions of this submission requiring confidential treatment as follows: 4,5,7,8,9,10,13,14,15.

  
  

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	 Mascoma Corporation, 1611380 Soldier Field Road, Boston, MA 0214202135
	  	617-234-0099    www.mascoma.com

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 Executive Summary 
 Commercial scale deployment of cellulosic ethanol technology integrated with biomass power and timber businesses - combining step change technology with complimentary wood fiber businesses to create a
sustainable cost advantage and a new business model for long term value creation in Michigan. 
 Project Objectives: 

 

	 	•	 	 Create sustainable cost advantage for “first of a kind” commercial scale cellulosic ethanol facility in MI 

 

	 	•	 	 Deploy step-change biological conversion technology targeted to provide lowest cost production 

 

	 	•	 	 Opportunity to integrate all value generating steps on one site to optimize fiber supply among complimentary industrial facilities

  

	 	•	 	 Build project finance requirements into business plan 

 

	 	•	 	 Create sustainable jobs in the State of MI 

 Frontier Renewable Resource Co, LLC (FRR) is an independent project entity jointly owned and capitalized by Mascoma Corporation and the JM Longyear LLC, based in Marquette, MI. The project partnership has
been formed specifically to design and construct a commercial scale cellulosic ethanol production facility. The project’s location in Kinross, MI in the Upper Peninsula provides several strategic advantages and affords an opportunity to
accelerate development of cellulosic ethanol as a direct result of the State’s forward thinking commitment to supporting renewable energy projects. Michigan’s vast timber resource, supply chain infrastructure and the State’s
technological universities offer research platforms and skills training to support an advanced bio-fuels industry. Additionally, the location chosen for the ethanol plant could serve as an “anchor” to attract the development of
complimentary fiber businesses, such as a lumber mill and a biomass power plant which would bring additional capital investment, jobs, economic benefits to Michigan and create a competitive cost advantage for the co-located businesses by more fully
utilizing a common supply of raw material. FFR could be competitively positioned to sustain an optimal return across all product lines through varying market conditions, while simultaneously reducing the risk of sustaining a first of a kind stand
alone cellulosic ethanol facility. 

  
  

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	 Mascoma Corporation, 1611380 Soldier Field Road, Boston, MA 0214202135
	  	617-234-0099    www.mascoma.com

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 Overview of Proposed Facilities 

 

	 	•	 	 Development and construction of new cellulosic ethanol bio-refinery 

 

	 	•	 	 Possible integration with known biomass energy and wood products manufacturing in single industrial facility 

 

	 	•	 	 Multiple end markets to limit single product risk 

  

	 	•	 	 Source all wood products / species efficiently for cost advantage 

 

	 	•	 	 Utilize internally generated waste to support all energy needs for facility 

 The commercial scale cellulosic ethanol facility will have a nameplate capacity of 20-40 million gallons per year. A prospective lumber milling facility and biomass power facility could derive its
primary fuel from bi-products from the cellulosic ethanol production process and will provide 100% of the steam and electricity needs for all of the co-located production facilities. A project site in Kinross, MI has been selected that offers rail,
interstate and lake access for inbound and outbound transportation needs. Proximity to hardwood feedstock catchments and multiple retail markets of scale have also been factored into the site selection process. 

Preliminary timelines established for the development of the cellulosic ethanol project targets completion of project feasibility steps within 18-24
months and facility commissioning by late 2011. Project feasibility steps will culminate in a commitment to finance construction of the facility, with all commitments targeted by April of 2010. Actual construction of the ethanol facility will
commence in May of 2010 and the facility would be commissioned in 2011. More aggressive timelines may be established for finance and construction of the prospective biomass power and sawmill facilities, which could deploy known engineering
technology in advantaged markets and therefore be able to support stand-alone investment. Additionally, Mascoma’s access to DOE funding for an expandable cellulosic ethanol facility in MI, also contemplated for the Kinross site, is scheduled
for design in 2009 which may accelerate overall site development activities and permitting for the commercial facility. 
 Key Strategic
Relationships 
  

	 	•	 	 Common vision - strategic alignment among operating partners 

 

	 	•	 	 Best in class technology, forestry, industrial and economic development capabilities 

 

	 	•	 	 Assembly of world-class, experienced project management team 

 

	 	•	 	 Complementary capital from DOE to accelerate development in MI 

 Frontier brings the best in class partners to execute the opportunity to commercialize low 

  
  

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	 Mascoma Corporation, 1611380 Soldier Field Road, Boston, MA 0214202135
	  	617-234-0099    www.mascoma.com

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cost cellulosic ethanol technologies. Anchor partners, Mascoma Corporation and JM Longyear, together deliver significant resources to the project. Significant cellulosic technology including
research and development, patents, licenses and engineering designs will be contributed by Mascoma. Feedstock contracting, forestry, logistics, industrial project development and project finance capabilities will be contributed by JM Longyear.
Additional operating relationships such as those chosen to develop the biomass power and lumber segments of the project will be evaluated and determined as part of the feasibility phase. 
 In addition to the operating entities that comprise Frontier, the project’s significant relationship with the State of Michigan, through the State’s economic development arm, the Michigan
Economic Development Corporation (MEDC), provides tremendous support in the areas of project funding, forestry policy, legislative initiatives and regulatory affairs. Two Michigan universities, Michigan Technological University and Michigan State
University, have teamed up to form a Center of Energy Excellence to focus on bio-fuel initiatives in the state. Frontier will contribute $2MM from its Michigan grant to these efforts and gain important support of forest management and sustainable
harvest optimization. Additional relationships with the Michigan Forest Product Council (legislative / public relations / regulatory and forestry policy), STS/AECOM Engineering (site engineering), Fagen Inc. (construction), Marathon Oil
(distribution), General Motors (fuels testing) and Miller Canfield (MI counsel) have been formed on behalf of the Frontier initiative. Mascoma’s partnership with the DOE has enabled an application for matching funds for preliminary engineering
and site infrastructure for the commercial scale facility and for critical path validation work to be completed in Mascoma’s expandable facility on site in Kinross and in Mascoma’s pilot plant in Rome, NY. 

[***] 

  
  

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	 Mascoma Corporation, 1611380 Soldier Field Road, Boston, MA 0214202135
	  	617-234-0099    www.mascoma.com

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 [***] 
 ]*) 
 Technology Summary 
 In the current economic and political climate, there has been enormous attention focused on the need to develop sustainable and renewable sources of transportation fuel. Ethanol has a significant and
growing role in this development, providing a cleaner, domestically-produced, renewable energy solution.
 However, the current generation of
ethanol production in the U.S. utilizes corn and other edible feedstocks. Mascoma is committed to developing sustainable, economically viable, next generation ethanol from cellulosic (non-food) feedstocks. In addition to using
non-

  
  

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	  	617-234-0099    www.mascoma.com

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food sources, processing ethanol from cellulosic biomass minimizes the environmental impact of fuel ethanol production through a more energy efficient process and lower greenhouse gas
emissions.
 Mascoma’s industry leading R&D team is focused on developing bio-fuels from non-food biomass wood, straws, dedicated
energy crops (e.g., switchgrass, miscanthus), paper pulp and other agricultural waste products. 
 In nature, no known organism is capable of
quickly and cost-effectively producing and fermenting sugars from cellulosic biomass. Mascoma’s research laboratories are now developing a new generation of microbes and processes for the economical conversion of cellulosic feedstocks into
ethanol and other end products.
 Mascoma is developing organisms and processes designed to: 

 

	 	•	 	 Rapidly break down the components of biomass 

  

	 	•	 	 Convert a range of sugars and polymers of sugars to ethanol 

 

	 	•	 	 Thrive in a manufacturing environment 

 Mascoma Corporation has the world’s largest research team focused on the commercial development of Consolidated Bio-Processing or CBP. We are harnessing the power of nature’s best
cellulose-utilizing and ethanol-fermenting microbes, simplifying the process and allowing nature to do most of the work. CBP is widely recognized as the simplest, lowest cost configuration for producing cellulosic ethanol. 

A simplified version of Mascoma’s process flow is illustrated in the diagram below: 

 
 

 
 Feedstock Plan 
 FRR’s initial raw material supply requirements will be 1 million wet ton’s of round wood annually for our 40 million gallons per year cellulosic ethanol plant. Our needs may be
greater in order to support the needs of our other integrated operations and potential ethanol plant expansion as demand for cellulosic ethanol grows. 

  
  

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	 Mascoma Corporation, 1611380 Soldier Field Road, Boston, MA 0214202135
	  	617-234-0099    www.mascoma.com

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 Our raw material supply strategy will be focused on long term volume supply commitments and supply chain
efficiencies (harvesting and transportation to our facility). Our objective is to optimize our raw materials yields and utilize internally generated waste throughout our integrated facility for cost efficiencies. This sourcing strategy combined with
our leading technology will lead to low cost and low carbon output of products. 
 Another integral part of our strategy has been to select the
optimum site for our facility. Specifically its proximity to our end markets, available infrastructure and proximity to our raw material needs. After much due diligence we have selected our site, located in Kinross Twp, Chippewa County, in the
eastern Upper Peninsula of Michigan. We believe our site is exceptional. It is located with access to abundant raw materials, has a well established supply chain network and possesses the required infrastructure (rail, roads and waterways). These
attributes will allow cost effective sourcing of raw materials. FRR will have access to a major north-south interstate highway, I-75, will be served by many major state and federal roads, have access to the Canadian National Railway (CN) along
with the great lakes waterways . 
 The timber resources are abundant in the area surrounding the Kinross site and more specifically from within
areas west, north and south of Kinross. The west encompasses both state forests (808,000 acres) and the federal Hiawatha National forest (1.04 million acres). In addition the area has an abundance of private landowners, both large and small. This
amounts to an estimated 4.5 million acres of timberlands. From the south are many large state forest management units in the northern Lower Peninsula. State owned timberlands makes up 598,000 acres within this area, with national forests
contributing 1.57 million acres and private landowners adding another 2.88 million acres. Forests are suitable for the project and the area is predominantly mixed hardwoods and pine forests, along with agricultural lands. Forest types
include red maple, oak, aspen, red pine and jack pine. Forestland ownership in this region (eastern UP and northern LP) is 38% private, 46% public (State and National forest) and 15% corporate. 

Phased Project Implementation Plan 
 The
objective of the MI project is to design and construct a commercial scale cellulosic ethanol facility with a name plate capacity of 40MMGY or greater. (*[We currently anticipate that this facility will be comprised of two 20MMGY production
lines.]*) In order to validate Mascoma’s conversion technology, production process and the costs for a full scale facility, Mascoma has established a phased roll out of increasingly larger unit operations, incorporating the learnings from
each development stage. Mascoma will 

  
  

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	 Mascoma Corporation, 1611380 Soldier Field Road, Boston, MA 0214202135
	  	617-234-0099    www.mascoma.com

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transition technology and process from the company’s existing pilot plant in Rome, NY directly into preliminary engineering and design for the MI facility, including infrastructure
requirements. Based on progress towards obtaining a process guarantee at each step, the first phase of the MI facility will validate technology and process sequentially while scaling up to the first 20MMGYproduction line. 

In order to off-set significant funding requirements for a staged gate development path, Mascoma has worked with the DOE under a competitive grant
process targeting cellulosic ethanol projects. Matching DOE funding will be used to fund detailed engineering and contribute to construction of the facility and accelerate MI’s development timeline. 

Projected Project Costs and Project Funding Plan 
 Mascoma is actively engaged in completing technology and engineering process validation in its Rome, NY pilot plant. Remaining work in Rome required to support the design and construction of the MI
facility will be funded by Mascoma with a sub-set of matching funds from a $26MM awarded to Mascoma by the DOE to construct a scale cellulosic ethanol facility. (*[The balance of the funds awarded to Mascoma under the grant program will fund the
Michigan commercial project. Under the DOE program’s matching funds requirement, monies received through MEDC’s grant to develop the MI commercial facility qualify as matching funds. The balance of funding for the Michigan project will be
comprised of equity investment and debt finance. 
 Please note that both equity and debt categories are included within the
‘Commercial Finance’ column in the chart below because ratios of each have not yet been established. Additional loan guarantees will be sought from existing DOE loan guarantee programs established to support first generation commercial
plants as well and would support debt sources included in this category.]*) 
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	 Mascoma Corporation, 1611380 Soldier Field Road, Boston, MA 0214202135
	  	617-234-0099    www.mascoma.com

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 [***] 
 Project Progress - August 2008 
  

	 	•	 	 Preliminary engineering and cost estimates completed for prototype commercial scale facility 

 

	 	•	 	 Commitment of financial and fiber supply support from MEDC 

 

	 	•	 	 Center of Energy Excellence project scope established with MSU and MTU 

 

	 	•	 	 Site selected in Kinross, MI 

  

	 	•	 	 Mascoma - JML Longyear partnership formation 

  

	 	•	 	 Project plan and budget completed for feasibility phase 

 

	 	•	 	 Preliminary approval to apply DOE funds awarded to Mascoma under 1/10th scale grant program to accelerate commercial deployment on Kinross site 

In July ‘07 Mascoma, together with BEK Engineering successfully completed preliminary designs and cost estimates for the construction of a 40MMGY
stand-alone cellulosic ethanol facility in MI. Following completion of the cost estimates, Mascoma initiated site selection and engaged in preliminary feasibility analysis on several promising project sites. In July 2008, Mascoma and partner JM
Longyear selected a site comprised of several hundred acres in the town of Kinross, MI in the eastern Upper Peninsula. This region is viewed as ideal as JM Longyear, with large forest land holdings

  
  

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	  	617-234-0099    www.mascoma.com

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in Michigan itself, has over 100 years of experience developing mining and timber projects in the region. In addition, MEDC and the Michigan’s Department of Natural Resources have begun
forming a strategy with an innovative structure designed to support Frontier while improving the health of its forests. In addition to feedstock supply chain support, MEDC has also made significant grant funds available to Mascoma in order to
initiate development of the Frontier project and participate in the Center of Excellence activities. Grant funding in this initial stage of the project is tied to project development milestones that have been established for the project feasibility
phase during which the Frontier team will finalize partnership agreements, engage in project engineering and design, complete permitting, secure feedstock contracts and off-take agreements and secure a full project financing commitment to construct
the project. Additionally, Mascoma has gained preliminary approval to apply funds awarded to Mascoma by the DOE to construct a pre-commercial scale facility in MI. (*[As a result, Mascoma will construct the pre-commercial scale facility as an
expandable +20MMGY first line of the planned 40MMGY commercial facility.]*) By developing the site to support the integration of both projects and timeline, Mascoma can accelerate the overall timeline to commercial scale production in MI by
approximately 6 months, while reducing the operational cost and risks. 
 Site Selected – Eastern UP Region 

(*[The project site in Kinross, MI has significant advantages* 
  

	 	•	 	 Strategic location to large refinery customers 

 

	 	•	 	 JM Longyear’s longstanding presence and project experience in the local area 

 

	 	•	 	 Close proximity to current Mascoma strategic investors (GM & Marathon) 

 

	 	•	 	 Infrastructure available (road, rail, transmission lines, pipeline to Detroit) 

 

	 	•	 	 Broad feedstock opportunities at site location, including Michigan wood basket (5th largest forested state, largest growing surplus in US); significant & logistically friendly Ontario wood
basket available. Strong possibility of plantations with current abandoned agricultural lands including hybrid aspen, willow plantations and grasses. 

 

	 	•	 	 300-400 acres available for site, improves efficient plant layout for operations and expansion, including co-locations with other fiber
businesses 

  

	 	•	 	 Proactive community supportive of development opportunities]*) 

  
  

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	 Mascoma Corporation, 1611380 Soldier Field Road, Boston, MA 0214202135
	  	617-234-0099    www.mascoma.com

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 Target project location in Kinross, MI 

 
 

 
  

  
  

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 Main interchange on I-75 

 
 

 
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SECTIONS REQUIRING CONFIDENTIAL TREATMENT ARE BOLDED AND NOTED WITH BRACKETS 

AND ASTERIX AS FOLLOWS: (*[bolded]*) 

			
	 Mascoma Corporation, 1611380 Soldier Field Road, Boston, MA 0214202135
	  	617-234-0099    www.mascoma.com

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 (*[Project Plan (CONFIDENTIAL) 

 

  
  

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	 Mascoma Corporation, 1611380 Soldier Field Road, Boston, MA 0214202135
	  	617-234-0099    www.mascoma.com

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SECTIONS REQUIRING CONFIDENTIAL TREATMENT ARE BOLDED AND NOTED WITH BRACKETS 

AND ASTERIX AS FOLLOWS: (*[bolded]*) 

			
	 Mascoma Corporation, 1611380 Soldier Field Road, Boston, MA 0214202135
	  	617-234-0099    www.mascoma.com

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 ]*) 
 APPENDIX A 
  

	 	1.	List of pages containing confidential information: 4,5,7,8,9,10,13,14,15  

 

  
  

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	 Mascoma Corporation, 1611380 Soldier Field Road, Boston, MA 0214202135
	  	617-234-0099    www.mascoma.com

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ATTACHMENT D 

UNITED STATES DEPARTMENT OF ENERGY LETTER 
 DATED SEPTEMBER 23, 2008 

  
 2 

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	 	 Department of Energy
 Golden Field Office
 1617 Cole Boulevard

Golden, Colorado 80401-3393
	 	

 SEP 23 2008 
 Mr. Justin van Rooyen 
 Director of Business Development 

Mascoma Corporation 
 1380 Soldiers Field Road

 Boston, MA 02135 
 Dear Mr. van
Rooyen: 
  

			
	SUBJECT:	 	Negotiation of Conditional Award No. DE-FC36-08GO18103, Amendment No. A000; “Demonstration of Integrated Biorefinery Application MAS10BIO5”

 The enclosed conditional award, executed on behalf of the U.S. Department of Energy (DOE), was prepared using your
application’s proposed budget information. Please refer to Attachment 1, Special Terms and Conditions, Provision 1 of the award, and note that DOE will not release funds obligated by the award until the final terms of
the award are approved by the Contracting Officer. All costs incurred prior to the approval of the final terms and conditions of the award, by the DOB Contracting Officer, are at your own risk. Please review the conditional award and sign Block
20 of both copies of the Notice of Financial Assistance Award (DOE Form 4600.1). Retain one copy of the award for your file and return the remaining copy to me no later than two weeks after the date of receipt 

Please complete the following actions (listed numerically) and documents (listed alphabetically) by March 31, 2009. All items must be submitted via
e-mail to me. 
 Actions include: 
  

	 	1.	External Independent Review conducted by DOE’s Independent Engineer; and 

 

	 	2.	Risk analysis conducted by Independent Project Analysis (EPA). 

 Documents include: 
  

	 	a.	Work Breakdown Structure (WBS) for the entire project, with detailed information for at least the work to be completed under Budget Period 1; 

 

	 	b.	Project Risk Mitigation Plan, including your response to the IPA report, that is satisfactory to DOE; 

 

	 	c.	Budget Information–Non Construction Programs, SF-424A; 

 (This form is available at https://www.eere-pmc.energy.gov/Forms.aspx). 
  

	 	d.	Budget Justification, PMC 123.1; and 

 (This form is available at https://www.eere-pmc.energy.gov/Forms.aspx. Note: Subrecipients/Subcontractors who are expected to perform work estimated to be 

 

					
	Federal Recycling Program	 	

	 	Printed on Recycled Paper

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	Mr. van Rooyen	 	 Page
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more than $100,000 or 50 percent of the total work effort (whichever is less) are required to provide: (1) separate SF-424A budget; (2) budget justification; (3) approved rate
agreement or proposal; and (4) description of work). 

  

	 	e.	Environmental Checklist, EF1 (This form should be completed on-line at (https://www.eere-pmc.energy.gov/nepa.asp). 

If you will be unable to provide the information by the date requested or have any questions concerning the requested information, please contact me at
(303) 275-4907 or via e-mail at melissa.wise@go.doe.gov. 
 The Financial Assistance Regulations and the Office of Management and
Budget (OMB). Circulars (http://www.whitehouse.gov/OMB/circulars/index.html) will assist you in understanding your requirements as an award recipient. In addition, please take a moment to read the Federal policies on lobbying activities
contained in DOE’s Lobbying Brochure found at https://www.eere-pmc.energy.gov/Forms.aspx. Organizations that receive financial assistance from DOE are required to post the Equal Opportunity Poster (DOE F 1600.4; also found at
https://www.eere-pmc.energy.gov/Forms.aspx. 
  

	
	Sincerely,
	
	 /s/ Melissa Wise

	Melissa Wise
	Grants and Agreements Specialist

 Enclosures 

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	Mr. van Rooyen	 	 Page
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 SPECIAL NOTICE 
 During fiscal years 2008 and 2009, the U.S. Department of Energy (DOE), will implement a new electronic procurement system. 
 As a result, DOE will also begin using a new communications portal as a means to post notices and solicitations as well as to communicate award activity (funding and non-funding) to awardees through the
lifecycle of an award. This new system is called FedConnect. 
 Upon implementation of the new electronic procurement system, all organizations
conducting (or wanting to conduct) business with DOE will be required to register in Fedconnect: 
  

	 	1.	The URL for the FedConnect site is https://www.FedConnect.net/FedConnect/. 

 

	 	2.	Register in FedConnect at https://www.fedconnect.net/FedConnect/PublicUserRegistration.aspx. 

 

	 	3.	To become familiar with the new procurement system, there is a “quick start guide” at https://www.FedConnect.net/FedConnect/PublicPages/FedConnect
Ready_Set_Go.pdf. 

  

	 	4.	Contact the helpdesk for FedConnect at support@fedconnect.net with any questions relative to registration. 

 

	 	5.	FedConnect requires all organizations to be registered with the CCR before registering with FedConnect. The CCR website is http://www.ccr.gov. Please ensure your
organization’s information is up-to-date in the CCR and that the information corresponds to the information with Dun and Bradstreet http://www.dnb.com/us/. 

 In consideration of system implementation, the DOE Golden Field Office strongly advises all current and potential contractors and financial assistance recipients to register with FedConnect as soon as
possible. 
 Thank you for your cooperation and understanding during this transition.

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