Document:

Severance Agreement and Release

 Exhibit 10.4 
  
 SEPARATION AGREEMENT AND RELEASE 
  
 This Separation Agreement and Release (“Agreement”) is entered into as of this fifteenth day of July, 2005
(hereinafter “Execution Date”) by and between Mark Frohlich (hereinafter “Employee”), and Xcyte Therapies, Inc., its affiliates, successors and assigns (hereinafter the “Company”). Employee and the Company are sometimes
collectively referred to as the “Parties.” 
  

	 	1.	Employee’s employment with the Company terminates effective July 15, 2005 (hereinafter “Termination Date”). The parties have agreed to avoid and resolve any alleged
existing or potential disagreements between them arising out of or connected with Employee’s employment with the Company. The Company expressly disclaims any wrongdoing or any liability to Employee. 

  

	 	2.	The Company agrees to provide Employee the following severance benefits, after the expiration of the seven-day revocation period described in Paragraph 9 below upon which the
Agreement becomes effective (hereinafter “Effective Date”), provided Employee has not revoked this Agreement as described in that Paragraph: 

  

	 	(a)	A lump sum payment in the gross amount of $55,966 which equals three (3) months base salary at Employee’s current rate. Standard employee withholding taxes and any amounts owed
by Employee to the Company will be deducted from this lump sum payment, in accordance with the Company’s regular payroll practices. Employee agrees that said payment will be mailed to Employee’s home on the next regular payroll date that
is at least five (5) calendar days after the Effective Date; 

  

	 	(b)	Upon Employee’s timely election of COBRA continuation coverage under the Company’s health plan, the Company will pay one hundred percent (100%) of the COBRA premium for
coverage through October 31, 2005; 

  

	 	(c)	If applicable, the Company will continue to administer Employee’s personal account within the Company’s existing 401(k) Plan, provided you meet the minimum balance
requirement; 

  

	 	(d)	Payment for any vacation time accrued above the current 120 hour vacation accrual payout limit (but below the 180 hour maximum), if applicable; and 

  

	 	(e)	 Vesting of Employee’s option(s) to purchase shares of Common Stock granted to Employee under the Company’s Amended and Restated 1996 Stock Option Plan
and/or 2003 Stock Plan will terminate July 12, 2005, (resulting in a total of 47,928 vested 

	 	 
option shares). No additional option shares shall vest after such date. In accordance with the terms of the Stock Option Agreement, the vested options will
be exercisable until October 12, 2005 (3 months following the Termination Date). Employee acknowledges and agrees that Employee has no other right, title or interest in or any Common Stock, stock options or any other capital stock of the Company as
of the Termination Date, except as provided for in this Agreement. 

  

	 	(f)	Final payment of home loan on or about September 15, 2005 

  
 Employee specifically acknowledges and agrees that this consideration exceeds the amount Employee would otherwise be entitled to receive upon termination
of Employee’s employment, and that this lump sum payment and other benefits are in exchange for entering into this Agreement. Employee agrees that Employee will not at any time seek consideration from the Company other than what is set forth in
this Agreement. Employee specifically acknowledges and agrees that the Company has made no representations to Employee regarding the tax consequences of any amounts received by Employee or for Employee’s benefit pursuant to this Agreement.

  

	 	3.	 Employee represents that Employee has not filed, and will not file, any complaints, lawsuits, administrative complaints or charges arising from or relating to
Employee’s recruitment by, employment with, or termination from, the Company. Notwithstanding any provision of law which provides that a general release does not extend to claims which the creditor does not know or suspect to exist in his favor
at the time of executing a release, Employee agrees to release the Company, its Board of Directors, officers, employees, agents and assigns, from any and all claims, charges, complaints, causes of action or demands of whatever kind or nature that
Employee now has or has ever had against the Company, whether known or unknown, arising from or relating to Employee’s recruitment by, employment with or discharge from the Company, including but not limited to: wrongful or tortious
termination, specifically including actual or constructive termination in violation of public policy; implied or express employment contracts and/or estoppel; discrimination and/or retaliation under any federal, state or local statute or regulation,
specifically including any claims Employee may have under the Fair Labor Standards Act, Age Discrimination in Employment Act, the Older Workers Benefit Protection Act, the Americans with Disabilities Act, Title VII of the Civil Rights Act of 1964 as
amended, and the Family and Medical Leave Act; the Washington Minimum Wage Act and the Washington Law Against Discrimination; any and all claims brought under any applicable federal, state or local employment discrimination or other statutes; any
claims brought under any federal or state statute or regulation for non-payment of wages, USERRA (Military Leave) or other compensation (including expense reimbursements and/or bonuses due after the Termination Date), including stock and stock
options; and libel, 

	 	 
slander, fraud, misrepresentation or breach of contract other than the breach of this Agreement. This release specifically excludes claims, charges,
complaints, causes of action or demands of whatever kind or nature that post-date the Termination Date or the Effective Date, whichever is later, and that are based on factual allegations that do not arise from or relate to Employee’s present
employment with or discharge from the Company. 

  

	 	4.	Employee acknowledges and affirms that Employee has previously executed a Proprietary Information and Inventions Agreement and that the terms and conditions of said agreement that
survive the employment relationship are not affected by this Separation Agreement and Release. Employee represents that Employee has returned all property belonging to the Company. Employee will direct all employment verification inquiries to the
Director of Human Resources. In response to inquiries regarding Employee’s employment with the Company, the Company, by and through its speaking agent(s) agrees to provide only the following information: Employee’s date of hire, the date
Employee’s employment ended and rates of pay. 

  

	 	5.	Employee warrants that no promise or inducement has been offered for this Agreement other than as set forth herein and that this Agreement is executed without reliance upon any
other promises or representations, oral or written. Any modification of this Agreement must be made in writing and be signed by Employee and the Company. This Agreement supersedes all prior understandings between the Parties and represents the
entire Agreement between the Parties with respect to all matters involving Employee’s employment with or termination from the Company. 

  

	 	6.	If any provision of this Agreement or compliance by Employee or the Company with any provision of this Agreement constitutes a violation of any law, or is or becomes unenforceable
or void, then such provision, to the extent only that it is in violation of law, unenforceable or void, will be deemed modified to the extent necessary so that it is no longer in violation of law, unenforceable or void, and such provision will be
enforced to the fullest extent permitted by law. If such modification is not possible, said provision, to the extent that it is in violation of law, unenforceable or void, will be deemed severable from the remaining provisions of this Agreement,
which provisions will remain binding on both Employee and the Company. This Agreement is governed by the laws of the State of Washington. 

  

	 	7.	 The King County Superior Court, Seattle, Washington shall have exclusive jurisdiction of any lawsuit arising from or relating to Employee’s employment with, or
termination from, the Company, or arising from or relating to this Agreement. Employee consents to such venue and personal jurisdiction. The prevailing party in any such lawsuit 

	 	 
will be entitled to an award of attorneys’ fees and reasonable litigation costs. Employee agrees that Employee will indemnify and hold the Company
harmless from any breach of this Agreement by Employee. Employee further agrees that if Employee challenges this Agreement or files any claims against the Company arising from or relating to Employee’s employment with, or termination from, the
Company, excluding any claim challenging the validity of Employee’s waiver of rights under the Age Discrimination in Employment Act, Employee will return all monies and benefits received by Employee from the Company pursuant to this Agreement.
In the event Employee challenges the validity of Employee’s waiver of rights under the Age Discrimination in Employment Act, Employee agrees that the Company may recover money and benefits paid under this Agreement if Employee’s challenge
and subsequent Age Discrimination in Employment Act claim are successful and Employee obtains a monetary award. 

  

	 	8.	Employee specifically agrees and acknowledges: (A) that Employee’s waiver of rights under this Agreement is knowing and voluntary as required under the Older Workers Benefit
Protection Act; (B) that Employee understands the terms of this Agreement; (C) that Employee has been advised in writing by the Company to consult with an attorney prior to executing this Agreement; (D) that the Company has given Employee a period
of up to forty-five (45) days within which to consider this Agreement; (E) that, following Employee’s execution of this Agreement Employee has seven (7) days in which to revoke Employee’s agreement to this Agreement and that, if Employee
chooses not to so revoke, the Agreement shall then become effective and enforceable and the payment and extension of benefits listed above shall then be made to Employee in accordance with the terms of this Agreement; and (F) nothing in this
Agreement shall be construed to prohibit Employee from filing a charge or complaint, including a challenge to the validity of the waiver provision of this Agreement, with the Equal Employment Opportunity Commission or participating in any
investigation conducted by the Equal Employment Opportunity Commission. However, Employee has waived any right to monetary relief. To cancel this Agreement, Employee understands that Employee must give a written revocation to Erin Shackelford,
Director of Human Resources at 1124 Columbia Street, Suite 130, Seattle, Washington, 98104, either by hand delivery or certified mail within the seven-day period. If Employee revokes the Agreement, it will not become effective or enforceable and
Employee will not be entitled to any of the benefits set forth above. 

  

	 	9.	Employee further specifically agrees that modifications to this Agreement, whether material or immaterial, do not restart the running of the forty-five (45) day period referenced in
Paragraph 9. 

 11. Exhibit A, attached hereto and incorporated herein, contains the eligibility criteria for
inclusion in the employment termination and severance package program, and Employee hereby acknowledges receipt of same. Exhibit B, entitled Employer Disclosure Regarding Ages of Individuals Selected and Not Selected for Severance Package,
attached hereto and incorporated herein, describes the ages and job titles of all persons selected for the layoff and eligible for the severance package, and the ages and job titles of all persons in the relevant job classification or department who
will not be laid off and Employee hereby acknowledges receipt of same. These attachments are provided to meet applicable legal requirements for group layoffs. 
  

12. EMPLOYEE ACKNOWLEDGES AND AGREES THAT EMPLOYEE HAS CAREFULLY READ AND VOLUNTARILY SIGNED THIS AGREEMENT, THAT EMPLOYEE HAS HAD AN OPPORTUNITY TO
CONSULT WITH AN ATTORNEY OF EMPLOYEE’S CHOICE, AND THAT EMPLOYEE SIGNS THIS AGREEMENT WITH THE INTENT OF RELEASING THE COMPANY AND ITS OFFICERS, DIRECTORS, EMPLOYEES AND AGENTS FROM ANY AND ALL CLAIMS. 
  
 ACCEPTED AND AGREED TO: 
  

					
	 	 	 	 	 
			
	 /s/ Robert Kirkman
	 	 	 	 /s/ Mark Frohlich

	 Robert Kirkman, M.D.
 Acting Chief Executive Officer
& President
 Xcyte Therapies, Inc.
	 	 	 	Mark Frohlich

  

							
	 Dated:
	  	 July 13, 2005
	  	Dated:	  	 July 26, 2005Retention and Separation Agreement

 Exhibit 10.5 
  
 XCYTE THERAPIES, INC. 
 RETENTION AND SEPARATION AGREEMENT 
  
 This Retention and
Separation Agreement (the “Agreement”) is dated as of July 26, 2005 (the “Effective Date”), by and between Kathi Lynn Cordova (“Employee”) and Xcyte Therapies, Inc., a Delaware corporation (the “Company”), and
sets forth the terms and conditions with respect to Employee’s employment with the Company as of and after the date of this Agreement. 
  
 Retention Benefits 
  
 On July 5, 2005, the Company issued a press release announcing its decision to implement a plan to identify and evaluate its strategic options. In
connection with such evaluation, on July 8, 2005, the Company’s Board of Directors approved a work force reduction plan that would result in the reduction of its work force by approximately 49%. The Company does not anticipate that any of the
remaining employees will be employed by the Company on a long-term basis and would like to retain Employee’s current position through a Retention Date. For purposes of this Agreement, the Retention Date shall be defined as the earlier of 1) the
Involuntary Termination of Employee’s current position with the Company without Cause or 2) the completion of a merger, acquisition, or other change of control or 3) immediately prior to the consummation of a proposed dissolution or liquidation
of the Company. 
  
 As an incentive for Employee to remain
employed from the date of this Agreement through the Retention Date, in addition to Employee’s regular salary, the Company will pay Employee the equivalent of two weeks base salary, less withholdings, for every full month from the July 1, 2005
through the Retention Date, and the payment shall be prorated for any partial months of employment. The retention benefit amount accrued will be paid within two weeks upon the Employee’s execution of a general release of claims, provided that
Employee remains employed through the Retention Date. If the Company terminates Employee’s employment for Cause (defined to be 1. conviction of any felony or a misdemeanor involving moral turpitude; 2. repeated failure to fulfill duties of job
position; 3. material violations of any Company work-related rule; 4. loss or withdrawal of a professional license otherwise required to fulfill Employee’s job duties), then Employee will not be entitled to receive any retention benefits.

  
 Separation Benefits 
  
 If at any time from the date of this agreement the Employee’s
employment with the Company is terminated under circumstances that constitute an Involuntary Termination without Cause, the Employee shall be entitled to receive separation benefits as set forth below, in addition to the retention benefits noted
above, provided Employee signs a general release of claims. 
  
 The separation benefit shall be equivalent to the severance benefit that Employee would have been entitled to under the standard severance package offered to all employees in the July 12, 2005 reduction-in-force. In accordance with the
standard 

 
severance package, Employee will receive a separation benefit to be calculated as follows. The benefit will be equal to a base of 4 weeks of base pay plus 3
weeks additional pay for every year of service on a prorated basis, with full monthly credit given for hire month and termination month. By way of example, as of July 12, 2005, the applicable benefit for Employee would have been equal to $ 116,011.
The separation benefit will be paid within two weeks following Employee’s execution of a general release of claims. 
  
 Additionally, the Employee shall be entitled to reimbursement for her expenses incurred in continuing her medical insurance for herself and her dependents
under the Consolidated Omnibus Budget Reconciliation Act of 1984, as amended (“COBRA”), as applicable, for a period of three (3) months following the commencement of such COBRA continuation coverage, provided Employee makes a timely
election for and continues to be eligible for such continued coverage. Any such reimbursement may be subject to withholding taxes as required by applicable law. 
  

Definition of “Involuntary Termination” 
  
 For purposes of this Agreement, Employee shall be considered to have been terminated under circumstances that constitute
Involuntary Termination if she is terminated by the Company or any successor without Cause (as previously defined), including but not limited to, 1) any merger, acquisition, dissolution or liquidation of the Company whereby the Company known as
Xcyte Therapies, Inc. ceases to exist and 2) any other circumstance where the Company is unable to retain Employee in her current position as the Principal Financial and Accounting Officer of the Company. 
  
 Voluntary Resignation 
  
 If Employee voluntarily elects to terminate Employee’s employment with
the Company, Employee shall not be entitled to any separation benefits. 
  
 Successors and Assigns 
  
 The rights and obligations under this Agreement shall benefit and be binding on any successor and/or assign of the Company, and the Company shall cause such successor and/or assign to agree expressly to perform the obligations under this
Agreement in the same manner and to the same extent as the Company would be required to perform such obligations in the absence of a succession. The terms of this Agreement and all of Employee’s rights hereunder shall inure to the benefit of,
and be enforceable by, Employee’s personal or legal representatives, executors, administrators, successors, heirs, distributes, devisees and legatees. Employee’s obligations under this Agreement may not be assigned. 
  
 Entire Agreement. 
  
 This Agreement is the entire agreement between the parties with respect to
the matters herein and supersedes all prior discussions and negotiations, except that, unless expressly modified herein, all of the employee’s existing terms and conditions of employment remain in effect, including the at-will employment
relationship. This agreement may only be modified expressly in a writing signed by both parties. 

 The parties have executed this Agreement the date first written above. 
  

			
	XCYTE THERAPIES, INC.
		
	By:	 	 /s/ Robert L. Kirkman

		
	 Title:
	 	 Acting President and Chief Executive Officer

			
		
	 Address:
	 	1124 Columbia Street, Suite 130 Seattle, Washington 98104
	
	 KATHI LYNN CORDOVA

		
	 Signature:
	 	/s/ Kathi Cordova

			
		
	 Address:
	 	 1215 18th Avenue
East Seattle,
 Washington 98112

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