Document:

EX-10.1

Exhibit 10.1

Execution Version

EXECUTIVE EMPLOYMENT AGREEMENT

This EXECUTIVE EMPLOYMENT AGREEMENT (this “Agreement”) is entered into as of September
6, 2011 (the “Effective Date”), by and between Cornerstone Therapeutics Inc., a Delaware
corporation (the “Company”), and Kenneth R. McBean (the “Executive”).

WHEREAS, the Company desires to employ the Executive and enter into this Agreement, which will
set forth the terms and conditions under which the Executive will serve the Company and its
affiliates; and

WHEREAS, the Executive wishes to be employed by the Company on the terms and conditions set
forth herein.

 

NOW, THEREFORE, in consideration of the premises and mutual agreements hereinafter contained,
the parties hereto agree as follows:

1. Term of Employment. The Company hereby agrees to employ the Executive, and the
Executive hereby accepts employment with the Company, upon the terms set forth in this Agreement,
for the period commencing on the Effective Date and ending on the date that the Agreement is
terminated in accordance with the provisions of Section 4.

2. Title; Capacity. The Executive shall serve as President and in such other
positions as the Company or its Board of Directors (the “Board”) may determine from time to
time. The Executive shall be based at the Company’s office in Cary, North Carolina. The Executive
shall be subject to the supervision of, and shall have such authority as is delegated to him by,
the Chief Executive Officer of the Company or his designee.

The Executive hereby accepts such employment and agrees to undertake the duties and
responsibilities inherent in such position and such other duties and responsibilities as the Chief
Executive Officer or his designee shall from time to time reasonably assign to him. The Executive
agrees to devote his entire business time, attention and energies to the business and interests of
the Company during the employment period; provided, however, that the Executive may
serve as a consultant or a member of an advisory board or a board of directors with the prior
consent of the Board. The Executive agrees to abide by any rules, regulations, instructions,
personnel practices and policies of the Company that are applicable to him and any changes therein
that may be adopted from time to time by the Company.

3. Compensation and Benefits.

3.1. Salary. The Company shall pay the Executive a base salary for the year starting
October 1, 2011 in accordance with its regular payroll practices at an annualized rate of $295,000,
less lawful deductions. Such salary shall be subject to adjustment thereafter as determined by the
Board.

3.2. Annual Target Cash Bonus. The Executive shall be eligible to receive an annual
target cash bonus of up to forty (40) percent of his then annual base salary (“Target Cash
Bonus”). The Board (or a committee thereof) shall determine the amount of the actual award, if
any, based on overall corporate performance and individual performance. Actual awards may be
greater than or less than the Executive’s Target Cash Bonus, depending in part upon the extent to
which actual performance exceeds or falls below the performance goals. Any bonus shall be paid in
a single lump sum, subject to lawful deductions, at such time as bonuses are regularly paid to
senior executives of the Company, but in any event such bonus shall be paid on or before March 15
of the year following the year to which the bonus relates. Except as may be expressly provided
below, the Executive must be employed on the date that the bonus is paid to be eligible for any
Target Cash Bonus. Each cash bonus award that may become payable shall be paid solely from the
general assets of the Company. Notwithstanding the foregoing, the Executive shall be eligible to
receive a Target Cash Bonus for 2011 of up to twelve and ninety-three hundredths (12.93%) of his
then annual base salary. The Executive shall be eligible to receive annual equity awards on
similar terms and conditions as may be applicable to other senior executives of the Company, and
the Compensation Committee of the Board shall determine the amount of the actual equity award, if
any. The Executive acknowledges that the Compensation Committee may consider that he was employed
by the Company for only 32.3% of the days in 2011 in determining the amount of his actual equity
award for such year.

3.3. Grant of Restricted Stock and Stock Options. The Executive will be granted,
effective as of the Effective Date, fifty thousand (50,000) shares of restricted common stock and
options to acquire seventy-five thousand (75,000) shares of common stock. The grant shall be on
such terms and conditions as are described in Appendix A hereto, and the documents
referenced therein.

3.4. Fringe Benefits. The Executive shall be entitled to participate in all bonus and
benefit programs (excluding the Company’s Cash Bonus Program for Employees (Other than Executive
Officers)) that the Company establishes and makes available to its employees or executives, if any,
to the extent that the Executive’s position, tenure, salary, age, health and other qualifications
make him eligible to participate; provided, however, the Executive’s participation
is subject to the applicable terms, conditions and eligibility requirements of these plans as they
may exist from time to time. The Executive shall be entitled to accrue 1.67 vacation days per
month (four (4) weeks per year), and, if requested in writing by the Chief Executive Officer, such
vacation time shall be taken at such times as may be approved by the Chief Executive Officer or his
designee. Accrued but unused vacation at the end of each year will not carry over past January 31
of the next year, except to the extent provided for in Company policies.

3.5. Reimbursement of Expenses. The Company shall reimburse the Executive for all
reasonable travel, entertainment and other expenses incurred or paid by the Executive in connection
with, or related to, the performance of his duties, responsibilities or services under this
Agreement, in accordance with the Company’s expense reimbursement policy, including the Executive’s
presentation of documentation, expense statements, vouchers and/or such other supporting
information as the Company may request, provided, however, that the amount
available for such travel, entertainment and other expenses may be fixed in advance by the Board.
Notwithstanding the foregoing, (i) the expenses eligible for reimbursement in any particular
taxable year may not affect the expenses eligible for reimbursement in any other taxable year,
(ii) such reimbursement must be made on or before the last day of the year following the year in
which the expense was incurred, and (iii) the right to reimbursement is not subject to liquidation
or exchange for another benefit.

3.6. Car Allowance. The Executive will receive a monthly car allowance in the amount
of $850. A valid driver’s license, an acceptable motor vehicle record and personal automobile
insurance are required at all times to operate a personal motor vehicle on Company business. The
Company reserves the right to change or discontinue its vehicle allowance program at any time.

4. Employment Termination. The employment of the Executive by the Company pursuant to
this Agreement shall terminate upon the occurrence of any of the following:

4.1. At the election of the Company, for Cause, immediately upon written notice by the Company
to the Executive;

4.2. At the election of the Executive, for Good Reason, upon written notice by the Executive
to the Company;

4.3. At the election of the Company without Cause during a Change of Control Period (as
defined in Section 20) or at the election of the Executive for Good Reason during a Change of
Control Period;

4.4. Upon the death or Disability (as defined in Section 20) of the Executive;

4.5. At the election of the Executive, without Good Reason, by providing written notice to the
Company at least ninety (90) days prior to such termination; and

4.6. At the election of the Company, without Cause, by providing written notice to the
Executive at least ninety (90) days prior to such termination.

5. Effect of Termination.

5.1. Termination for Cause. In the event the Executive’s employment is terminated for
Cause pursuant to Section 4.1, the Company shall pay to the Executive the compensation and benefits
otherwise payable and expenses otherwise reimbursable to him under Section 3 through the last day
of his actual employment by the Company.

5.2. Termination at the Election of the Executive Without Good Reason. In the event
the Executive elects to terminate his employment pursuant to Section 4.5, the Company shall pay the
Executive the compensation and benefits otherwise payable and expenses otherwise reimbursable to
him under Section 3 through the last day of his actual employment by the Company. Executive shall
not be liable to the Company for any damages arising from or associated with the Company’s not
having a President during any period following a termination by the Executive of his employment and
this Agreement pursuant to Section 4.5.

5.3. Termination for Death or Disability. If the Executive’s employment is terminated
by death or because of Disability pursuant to Section 4.4, in addition to any disability or life
insurance benefits for which the Executive or the estate of the Executive may be eligible, the
Company shall pay to the estate of the Executive or to the Executive, as the case may be, the
compensation and benefits otherwise payable and expenses otherwise reimbursable to him under
Section 3 through the last day of his actual employment by the Company. In addition, if the
Executive’s employment terminates as a result of his death, the Executive’s estate shall receive an
amount equal to a pro rata payment of the annual cash bonus for which he would have been eligible,
less lawful deductions, within ten (10) calendar days following the effective date of the Release
required by Section 5.6, but not later than ninety (90) days following termination of employment.
Notwithstanding the foregoing, if the ninetieth (90th) day following the Executive’s termination
from employment occurs in the calendar year following the year of the Executive’s termination, then
the payment shall be made no earlier than January 1 of such subsequent calendar year. No other
benefits are payable upon the Executive’s termination pursuant to Section 4.4.

5.4. Termination Without Cause or for Good Reason and not during a Change of Control
Period. Provided that the Company has not provided notice of termination without Cause to the
Executive pursuant to Section 4.6 prior to the first anniversary of the Effective Date (such
anniversary date, the “Benefit Date”), if the Executive’s employment is terminated without Cause
pursuant to Section 4.6, or for Good Reason pursuant to Section 4.2, and such termination does not
occur during a Change of Control Period, the Company shall:

(a) pay the Executive the compensation and benefits otherwise payable and expenses otherwise
reimbursable to him under Section 3 through the last day of his actual employment by the Company;

(b)  pay the Executive a lump sum payment equal to one (1) times his annualized base salary,
less lawful deductions, payable within ten (10) calendar days following the effective date of the
Release required by Section 5.6 but not later than ninety (90) days following termination of
employment. Notwithstanding the foregoing, if the ninetieth (90th) day following the
Executive’s termination from employment occurs in the calendar year following the year of the
Executive’s termination, then the payment shall be made no earlier than January 1 of such
subsequent calendar year;

(c)  pay on behalf of the Executive, in accordance with the Company’s regular payroll
practices, on a monthly basis an amount equal to (i) one hundred (100) percent of the Executive’s
monthly health and dental COBRA premiums for the Executive and his dependents, if any, if the
Executive properly elects to continue health and dental insurance under COBRA and (ii) pay to the
Executive on the first business day of each applicable month one hundred (100) percent of the cost
of the monthly premiums paid by the Company to the insurance companies for life insurance and
disability insurance for the Executive in the month preceding the Executive’s termination of
employment, such payments under subsections (i) and (ii) to continue until the earlier of (x)
twelve (12) months after the termination of the Executive’s employment and (y) the last day of the
first month that the Executive is eligible for other employer-sponsored health coverage.
Notwithstanding the foregoing, to the extent such payments are reimbursement to the Executive of
medical expenses incurred by the Executive as described in Reg. § 1.409A-1(b)(9)(v)(B),
reimbursements may not be made beyond the period of time during which the Executive would be
entitled (or would, but for such arrangement, be entitled) to COBRA continuation coverage under a
group health plan of the Company;

(d)  pay the Executive a lump sum payment in an amount equal to a pro rata payment of the
Target Cash Bonus for which he was eligible, less lawful deductions; such payment shall be paid
within ten (10) calendar days following the effective date of the Release required by Section 5.6,
but not later than ninety (90) days following termination of employment. Notwithstanding the
foregoing, if the ninetieth (90th) day following the Executive’s termination from
employment occurs in the calendar year following the year of the Executive’s termination, then the
payment shall be made no earlier than January 1 of such subsequent calendar year; and

(e)  accelerate vesting of all of the Executive’s outstanding unvested stock options and
restricted stock by one year.

5.5. Termination Without Cause or for Good Reason during a Change of Control Period.
If the Executive’s employment is terminated without Cause pursuant to Section 4.3, or for Good
Reason pursuant to Section 4.3, and such termination occurs during a Change of Control Period, the
Company shall:

(a) pay the Executive the compensation and benefits otherwise payable and expenses otherwise
reimbursable to him under Section 3 through the last day of his actual employment by the Company;

(b)  pay the Executive a lump sum payment equal to one (1) times his annualized base salary,
less lawful deductions, payable within ten (10) calendar days following the effective date of the
Release required by Section 5.6, but not later than ninety (90) days following termination of
employment. Notwithstanding the foregoing, if the ninetieth (90th) day following the
Executive’s termination from employment occurs in the calendar year following the year of the
Executive’s termination, then the payment shall be made no earlier than January 1 of such
subsequent calendar year;

(c)  pay on behalf of the Executive, in accordance with the Company’s regular payroll
practices, on a monthly basis an amount equal to (a) one hundred (100) percent of the Executive’s
monthly health and dental COBRA premiums for the Executive and his dependents, if any, if the
Executive properly elects to continue health and dental insurance under COBRA and (b) pay to the
Executive on the first business day of each applicable month one hundred (100) percent of the cost
of the monthly premiums paid by the Company to the insurance companies for life insurance and
disability insurance for the Executive in the month preceding the Executive’s termination of
employment, such payments under subsections (a) and (b) to continue until the earlier of (x) twelve
(12) months after the termination of the Executive’s employment and (y) the last day of the first
month that the Executive is eligible for other employer-sponsored health coverage. Notwithstanding
the foregoing, to the extent such payments are reimbursement to the Executive of medical expenses
incurred by the Executive as described in Reg. § 1.409A-1(b)(9)(v)(B), reimbursements may not be
made beyond the period of time during which the Executive would be entitled (or would, but for such
arrangement, be entitled) to COBRA continuation coverage under a group health plan of the Company;

(d)  pay the Executive a lump sum payment in an amount equal to a pro rata payment of the
Target Cash Bonus for which he was eligible, less lawful deductions; such payment shall be paid ten
(10) calendar days following the effective date of the Release required by Section 5.6, but not
later than ninety (90) days following termination of employment. Notwithstanding the foregoing, if
the ninetieth (90th) day following the Executive’s termination from employment occurs in the
calendar year following the year of the Executive’s termination, then the payment shall be made no
earlier than January 1 of such subsequent calendar year; and

(e)  accelerate vesting of one hundred (100) percent of all of the Executive’s outstanding
unvested stock options and restricted stock.

5.6. Conditions to Payment.

(a) Notwithstanding any provision of this Agreement to the contrary, the Company’s obligation
to provide the payments and benefits under Sections 5.3, 5.4, and 5.5 is conditioned upon the
Executive’s, or the Executive’s estate’s, execution of a severance agreement and full release of
all claims against the Company and all affiliated persons and entities, drafted by and reasonably
satisfactory to counsel for the Company (the “Release”), and the Executive’s compliance
with Sections 7 and 8 of this Agreement. The Release shall include clauses covering
confidentiality, non-disparagement, cooperation, and non-admissions, among other terms, all in a
form reasonably acceptable to the Company. The Executive, at his expense, may consult with legal
counsel and may propose revisions to the Release, which the Company agrees to consider in good
faith. If the Executive chooses not to execute such a release or fails to comply with those
Sections, then the Company’s obligation to compensate the Executive ceases on the effective
termination date except as to base salary up through the termination date. The Release shall be
provided to the Executive within thirty (30) days of the Executive’s separation from service and
the Executive must execute it within the time period specified in the Release (which shall not be
longer than forty-five (45) days from the date of receipt). Such Release shall not be effective
until any applicable revocation period specified therein has expired.

(b) Notwithstanding any provision of this Agreement to the contrary, the Company’s obligation
to provide the payments and benefits under Section 5.4 shall not arise until the Benefit Date and
is expressly conditioned upon the Executive remaining an employee in good standing with the Company
through the Benefit Date.

6. Vesting of Stock Upon a Change of Control. One hundred (100) percent of the
Executive’s outstanding unvested stock options and restricted stock will vest on a Change of
Control (as defined in Section 20).

7. Non-Compete.

7.1. During the Executive’s employment with the Company and for a period of one year following
the cessation thereof, the Executive will not engage in any of the following on his own behalf or
in any capacity on another’s behalf:

(a) engage in any business activity (or assist others to engage in any business activity) that
directly competes with the Company; or

(b) have any interest in any business that directly competes with the Company; or

(c) be employed (or otherwise engaged) in (A) a management capacity, (B) other capacity
providing the same or similar services which the Executive provided to the Company, or (C) any
capacity connected with competitive business activities, by any person or entity that engages in
the same, similar or otherwise competitive business as the Company.

The restrictions set forth in subparagraphs 7.1(a)–(c) shall apply in the following severable
geographic areas: (i) the Raleigh-Cary-Durham-Chapel Hill, NC metropolitan areas; (ii) any city,
metropolitan area, county, state (or similar political subdivisions in foreign countries) in which
the Company is located or does or, during the last twelve (12) months of the Executive’s employment
with the Company, did business; (iii) any city, metropolitan area, county, or state (or similar
political subdivisions in foreign countries) in which the Executive’s services were provided, or
for which the Executive had responsibility, or in which the Executive worked on Company projects,
during the last twelve (12) months of the Executive’s employment with the Company; or (iv) the
entire United States of America and its territories.

7.2. During the Executive’s employment with the Company and for a period of one (1) year
following the cessation thereof (whether voluntary or involuntary and regardless of the reason for,
or party initiating, the termination), the Executive will not engage in any of the following on his
own behalf or in any capacity on another’s behalf, directly or indirectly:

(a) solicit, persuade, induce, encourage or attempt to solicit, persuade, induce or encourage
any person to leave his or her employment with the Company or to refrain from providing services to
the Company; or

(b) induce or attempt to induce (including, without limitation, by soliciting business from),
or otherwise encourage or assist, any customer, client, or business relation of the Company with
which the Executive had contact on behalf of the Company (i) to cease doing business with the
Company or reduce the level of business it conducts with the Company, or (ii) to purchase or
promote any prescription pharmaceutical product that competes directly with the Company’s products
for the treatment of any indication for which the Company has received United States Food and Drug
Administration (“FDA”) approval or for an indication which the Company’s products are being
developed or may be developed.

Upon cessation of the Executive’s employment with the Company, the Executive will sever all
marketing and sales relationships with customers of the Company and the Executive agrees that any
attempt to retain these customers for his own or another’s benefit will be a material breach of
this Agreement.

7.3. The Executive agrees that, if requested by the Company in writing, he will give notice to
the Company of each new business activity he plans to undertake during the non-competition period,
at least ten (10) business days prior to beginning any such activity. The notice shall state the
name and address of the individual, corporation, association or other entity or organization
(“Entity”) for whom such activity is undertaken and the name of the Executive’s business
relationship or position with the entity. The Executive further agrees to provide the Company with
other pertinent information concerning such business activity as the Company may reasonably request
in order to determine the Executive’s continued compliance with his obligations under this
Agreement. The Executive agrees that, if requested by the Company in writing, he will provide a
copy of Sections 7 and 8 of this Agreement to all persons and Entities with whom he seeks to be
hired or do business before accepting employment or engagement with any of them.

7.4. If any restriction set forth in this Section 7 is found by any court of competent
jurisdiction to be unenforceable because it extends for too long a period of time or over too great
a range of activities or in too broad a geographic area, it shall be interpreted to extend only
over the maximum period of time, range of activities or geographic area as to which it may be
enforceable.

7.5. The Executive acknowledges that the restrictions contained in this Section are necessary
for the protection of the business and goodwill of the Company and in light of, among other things,
the highly competitive market in which the Company operates. The Executive agrees that any breach
of this Section will cause the Company substantial and irreparable damage and therefore, in the
event of any such breach, in addition to such other remedies which may be available, the Company
shall have the right to seek specific performance and injunctive relief without posting a bond.

7.6. If the Executive violates the provisions of this Section 7, he shall continue to be held
by the restrictions set forth in this Section, until a period equal to the period of restriction
has expired without any violation.

8. Proprietary Information and Developments.

8.1. Proprietary Information.

(a) The Executive agrees that all information and know-how, whether or not in writing, of a
private, secret or confidential nature concerning the Company’s business or financial affairs
(collectively, “Proprietary Information”) is and shall be the exclusive property of the
Company. By way of illustration, but not limitation, Proprietary Information may include
inventions, products, processes, methods, techniques, formulas, compositions, compounds, projects,
developments, plans, research data, clinical data, financial data, personnel data, computer
programs, and customer and supplier lists. The Executive will disclose Proprietary Information
solely to employees, officers, and directors of the Company and only on a need-to-know basis and
will use the same solely for purposes of performing the Executive’s duties and responsibilities on
behalf of Company as described in Section 2 hereof, unless otherwise permitted by prior written
approval of an officer of the Company. Developments (defined in Section 8.2(a) below) shall
constitute Proprietary Information of Company for all purposes hereunder.

(b) The Executive agrees that all files, letters, memoranda, reports, records, data, sketches,
drawings, laboratory notebooks, program listings, or other written, photographic, or other tangible
material containing Proprietary Information, whether created by the Executive or others, which
shall come into his custody or possession, shall be and are the exclusive property of the Company
to be used by the Executive only in the performance of his duties for the Company.

(c) The Executive agrees that his obligations set forth in paragraphs (a) and (b) above also
extend to such types of information, know-how, records and tangible property of customers of the
Company or suppliers to the Company or other third parties who may have disclosed or entrusted the
same to the Company or to the Executive in the course of the Company’s business.

8.2. Developments.

(a) The Executive will make full and prompt disclosure to the Company of all inventions,
discoveries, processes, methods, developments, software, and works of authorship, whether or not
patentable or copyrightable, which are created, made, conceived or reduced to practice by the
Executive or under his direction or jointly with others during his employment by the Company,
whether or not during normal working hours or on the premises of the Company (all of which, along
with all improvements, modifications, and derivative works thereof and thereto and all proprietary
know-how and other information associated therewith, are collectively referred to in this Agreement
as “Developments”).

(b) The Executive agrees to irrevocably and unconditionally assign, and does hereby
irrevocably and unconditionally assign, to the Company (or any person or entity designated by the
Company) and to forever waive and never assert any and all of his right, title and interest in and
to all Developments and all related patents, patent applications, copyrights, copyright
registration applications, and other intellectual property rights and moral rights associated
therewith. The rights assigned to Company herein shall include, without limitation, the rights (i)
to bring claims and causes of action for damages and other relief by reason of all past and future
infringements, misappropriations, or other violations of any and all rights under such
Developments; (ii) to collect and enjoy damages, benefits, and other remedies resulting therefrom;
and (iii) to charge and collect royalties or other payments arising out of or relating to the grant
of licenses or similar rights under any such Developments.

(c) The Executive agrees to cooperate fully with the Company, both during and after his
employment with the Company, with respect to the prosecution, procurement, maintenance, enforcement
and/or defense of patents, trademarks, copyrights, trade secrets and other means for protection of
the Developments (both in the United States and foreign countries). The Executive shall sign all
papers, including, without limitation, copyright registration applications, patent applications,
declarations, oaths, formal assignments, assignment of priority rights, and powers of attorney,
which the Company may deem necessary or desirable in order to protect its rights and interests in
any Development. The Executive shall further execute and deliver all such instruments and take all
other actions as in the opinion of the Company and its counsel shall be appropriate to vest in the
Company (or in such person as the Company may specify) all right, title and interest in said
Developments and any patents, trademarks, copyrights, trade secrets and other intellectual property
rights associated therewith. The Executive shall be entitled to reasonable compensation for all
time devoted to such post-employment cooperation at a rate equal to three hundred dollars ($300)
per hour.

(d) Whenever requested to do so by the Company, both during and after his employment with the
Company, and at the expense of the Company, the Executive shall cooperate fully and assist the
Company in the defense or prosecution of any claims or actions now in existence or which may be
brought in the future in connection with (i) any litigation commenced by the Company against third
parties, (ii) any litigation commenced by a third party against the Company and (iii) any
administrative hearing or administrative proceeding involving the Company. The Executive’s full
cooperation in connection with any claims, actions or administrative proceedings shall include, but
not be limited to, his being available to meet with the Company’s counsel to prepare for trial,
discovery or an administrative hearing and to act as a witness when requested by the Company at
reasonable times designated by the Company. The Executive shall be entitled to reasonable
compensation for all time devoted to such post-employment cooperation at a rate equal to three
hundred dollars ($300) per hour.

(e) The Executive hereby irrevocably appoints the Company to be his attorney in fact and, in
his name and on his behalf, to execute all such instruments and take all other actions and
generally to use his name for the purpose of providing to the Company the full benefit of the
provisions of subsections 8.2(b) and 8.2(c).

(f) The Executive hereby waives and quitclaims to the Company any and all claims, of any
nature, which the Executive now or may hereafter have for infringement, misappropriation, or other
violation of any Development assigned hereunder to the Company.

(g) The Executive acknowledges and agrees that all original works of authorship which are
created by the Executive (solely or jointly with others) within the scope of the Executive’s
employment and which are protectable by copyright are “works made for hire,” as that term is
defined in the United States Copyright Act (17 U.S.C. Section 101).

(h) The Executive represents and warrants that to the extent applicable, the Executive has
provided to the Company a list entitled “List of Inventions,” that a true and complete list of all
inventions, discoveries, methods, processes, developments, software, and works of authorship,
whether or not patentable or copyrightable, which were created, made, conceived or reduced to
practice by the Executive, whether solely or jointly with others, prior to his employment by the
Company (collectively, “Inventions”). Any improvements to or derivative works of any such
Inventions, whether or not patentable or copyrightable and whether or not reduced to practice,
conceived or created after commencement of the Executive’s employment by the Company shall
constitute Developments for all purposes hereunder to the extent arising out of or relating to any
use of or other reliance on any Proprietary Information by or on behalf of the Executive.

8.3. Other Agreements. Other than as previously disclosed to the Company by the
Executive in writing, the Executive hereby represents that he is not bound by the terms of any
agreement with any previous employer or other party to refrain from using or disclosing any trade
secret or confidential or proprietary information in the course of his employment with the Company
or to refrain from competing, directly or indirectly, with the business of such previous employer
or any other party. The Executive further represents that his performance of all the terms of this
Agreement and as an executive officer of the Company does not and will not breach any agreement to
keep in confidence proprietary information, knowledge or data acquired by him in confidence or in
trust prior to his employment with the Company.

9. Other Severance Arrangements. The benefits under this Agreement will be provided
in lieu of benefits under any severance plan of the Company or under the Executive’s offer letter.
The Executive acknowledges and agrees that the acceleration of vesting of stock options and
restricted stock under this Agreement is in lieu of any acceleration of vesting of stock options
and restricted stock upon a change of control under the Company’s current and any future stock
option plans, including, but not limited to, the Company’s 2000 Equity Incentive Plan, 2003 Stock
Incentive Plan, 2004 Stock Incentive Plan, the Cornerstone BioPharma Holdings, Inc. 2005 Stock
Option Plan, and the Cornerstone BioPharma Holdings, Inc. 2005 Stock Incentive Plan, each as
amended from time to time.

10. Mitigation. The Executive has no obligation to mitigate amounts payable under
this Agreement by seeking other employment.

11. Notices. All notices required or permitted under this Agreement shall be in
writing and shall be deemed effective upon personal delivery or upon deposit in the United States
Post Office, by registered or certified mail, postage prepaid, if to the Company, at its principal
office addressed to the attention of Craig Collard, CEO, and if to the Executive, at the address
specified in his most recently submitted IRS Form W-4, or at such other address or addresses as
either party shall designate to the other in accordance with this Section 11.

12. Pronouns. Whenever the context may require, any pronouns used in this Agreement
shall include the corresponding masculine, feminine or neuter forms, and the singular forms of
nouns and pronouns shall include the plural, and vice versa.

13. Entire Agreement. This Agreement constitutes the entire understanding between the
parties hereto with respect to the subject matter hereof, and this Agreement supersedes and renders
null and void any and all prior oral or written agreements, understandings or commitments
pertaining to the subject matter hereof. To the extent this Agreement is inconsistent or conflicts
with any other agreement entered into between the Executive and the Company, including any option
or restricted stock award agreements, this Agreement shall control.

14. Amendment. This Agreement may be amended or modified only by a written instrument
executed by both the Company and the Executive.

15. Governing Law. This Agreement shall be interpreted and enforced in accordance
with the laws of the State of North Carolina without regard to conflict of laws provisions.

16. Successors and Assigns. This Agreement shall be binding upon and inure to the
benefit of both parties and their respective successors and assigns, including any corporation with
which or into which the Company may be merged or which may succeed to its assets or business,
provided, however, that the obligations of the Executive are personal and shall not be assigned by
the Executive.

17. Dispute Resolution. Any claim or controversy arising out of or relating to this
Agreement, or any breach thereof, or otherwise arising out of or relating to the Executive’s
employment, compensation and benefits with the Company or the termination thereof, including any
claim for discrimination under any local, state or federal employment discrimination law, except as
specifically excluded herein, shall be brought in only in a court of the State of North Carolina
(or, if appropriate, a federal court located within the State of North Carolina), and the Company
and the Executive each consents to the jurisdiction of such a court. Both the Company and the
Executive expressly waive any right that any party either has or may have to a jury trial of any
dispute arising out of or in any way related to the Executive’s employment with or termination from
the Company. The Executive expressly acknowledges and agrees that he hereby waives any right to
claim or recover punitive damages.

18. Acknowledgment. THE EXECUTIVE ACKNOWLEDGES THAT HE HAS HAD A REASONABLE PERIOD
SUFFICIENT TO STUDY, UNDERSTAND AND CONSIDER THIS AGREEMENT, THAT HE HAS HAD AN OPPORTUNITY TO
CONSULT WITH LEGAL COUNSEL OF HIS CHOICE, THAT HE HAS READ THIS AGREEMENT AND UNDERSTANDS ALL OF
ITS TERMS, THAT HE IS ENTERING INTO AND SIGNING THIS AGREEMENT KNOWINGLY AND VOLUNTARILY, AND THAT
IN DOING SO HE IS NOT RELYING UPON ANY STATEMENTS OR REPRESENTATIONS BY THE COMPANY OR ITS AGENTS.

19. Miscellaneous.

19.1. No delay or omission by the Company in exercising any right under this Agreement shall
operate as a waiver of that or any other right. A waiver or consent given by the Company on any
one occasion shall be effective only in that instance and shall not be construed as a bar or waiver
of any right on any other occasion.

19.2. The captions of the sections of this Agreement are for convenience of reference only and
in no way define, limit or affect the scope or substance of any section of this Agreement.

19.3. In case any provision of this Agreement shall be invalid, illegal or otherwise
unenforceable, the validity, legality and enforceability of the remaining provisions shall in no
way be affected or impaired thereby.

19.4. Nothing in this Agreement should be construed to create a trust or to establish or
evidence the Executive’s claim of any right to payment other than as an unsecured general creditor
with respect to any payment to which the Executive may be entitled.

19.5. The provisions of Sections 5, 7, 8, 15, 17 and 21 shall survive the termination of this
Agreement.

19.6. Upon termination of the Executive’s employment by the Company for any reason whatsoever
whether voluntarily or involuntarily, or at any other time upon the Company’s request, the
Executive agrees to promptly return to the possession of the Company any materials or copies
thereof, in hard copy or electronically, containing and/or pertaining to Proprietary Information
relating to the Company or any of its subsidiaries or affiliates and shall not take any material or
copies thereof from the possession of the Company, or destroy any such materials. In addition, the
Executive shall also return to the Company all Company property and equipment in the Executive’s
possession or control, including but not limited to, all documents, product samples, tapes, notes,
computer files, equipment, phone, facsimile, printer, computer, physician lists, employee lists,
lab notebooks, files, computer equipment, security badges, telephone calling cards, credit cards,
and other information or materials (and all copies) which contain confidential, proprietary or
non-public information of the Company. The Executive further agrees to leave intact all electronic
Company documents on the Company’s servers or computers, including those which the Executive
developed or helped develop during the Executive’s employment. The Executive further agrees to
promptly return or make available to the Company or its agents any motor vehicle provided to the
Executive by the Company.

 

20. Definitions.

20.1. For purposes of this Agreement, “beneficial ownership” shall have the meaning
set forth in Rule 13d-3 promulgated under the Exchange Act, and “beneficially own(s)” and
“beneficially owned” shall have correlative meanings.

20.2. For the purposes of this Agreement, “Cause” for termination shall be deemed to
exist upon (a) the Executive’s use of alcohol or narcotics which proximately results in the willful
material breach or habitual willful neglect of the Executive’s duties under this Agreement; (b) the
Executive’s criminal conviction of fraud, embezzlement, misappropriation of assets, or the
Executive’s conviction of any felony or crime of moral turpitude, but in no event traffic
or similar violations; (c) any act of the Executive constituting willful misconduct which is
materially detrimental to the Company’s best interests, including but not limited to
misappropriation of, or intentional damage to, the funds, property or business of the Company; (d)
except with regard to violation of Company policies prohibiting harassment or discrimination, the
Executive’s material violation of the Company’s policies if such violations are not cured or ended
within thirty (30) days after notice thereof by the Company specifying the nature of such material
violation; (e) the Executive’s material violations of the Company’s policies prohibiting harassment
or discrimination; or (f) the Executive’s willful Material Breach (as defined below) of this
Agreement, if such willful Material Breach is not cured by the Executive within thirty (30) days
after the Company’s written notice thereof specifying the nature of such willful Material Breach.
“Material Breach” shall mean (x) the substantial and continual willful nonperformance of
the Executive’s material duties under this Agreement resulting from the Executive’s gross
negligence or willful misconduct which the Board reasonably determines has resulted in material
injury to the Company or (y) the breach of Section 7 or Section 8 of this Agreement.

20.3. For purposes of this Agreement, a “Change of Control” shall mean:

(a) the acquisition by an individual, entity or group (within the meaning of Section
13(d)(3) or 14(d)(2) of the Exchange Act (as defined below)) (a “Person”), other than
Chiesi Farmaceutici SpA or any of its affiliates, of beneficial ownership of any capital stock of
the Company if prior to such acquisition such Person did not, and after such acquisition such
Person does, beneficially own fifty percent (50%) or more of the combined voting power of the
then-outstanding securities of the Company entitled to vote generally in the election of directors
(the “Outstanding Company Voting Securities”); or

(b) such time as the Continuing Directors (as defined below) do not constitute a majority of
the Board (or, if applicable, the Board of Directors of a successor corporation to the Company),
where the term “Continuing Director” means at any date a member of the Board (x) who was a
member of the Board on the date of the initial adoption of the Employment Agreement by the Board or
(y) who was nominated or elected subsequent to such date by at least a majority of the directors
who were Continuing Directors at the time of such nomination or election or whose election to the
Board was recommended or endorsed by at least a majority of the directors who were Continuing
Directors at the time of such nomination or election; provided, however, that there shall be
excluded from this clause (y) any individual whose initial assumption of office occurred as a
result of an actual or threatened election contest with respect to the election or removal of
directors or other actual or threatened solicitation of proxies or consents, by or on behalf of a
person other than the Board; or

(c) the consummation of a merger, consolidation, reorganization, recapitalization or share
exchange involving the Company or a sale or other disposition of all or substantially all of the
assets of the Company (a “Business Combination”), unless, immediately following such
Business Combination, each of the following two conditions is satisfied: (x) all or substantially
all of the individuals and entities who were the beneficial owners of the Outstanding Company
Voting Securities immediately prior to such Business Combination beneficially own, directly or
indirectly, more than fifty percent (50%) of the combined voting power of the then-outstanding
securities entitled to vote generally in the election of directors, respectively, of the resulting
or acquiring corporation in such Business Combination (which shall include, without limitation, a
corporation which as a result of such transaction owns the Company or substantially all of the
Company’s assets either directly or through one or more subsidiaries) (such resulting or acquiring
corporation is referred to herein as the “Acquiring Corporation”) in substantially the same
proportions as their ownership of the Outstanding Company Voting Securities immediately prior to
such Business Combination and (y) no Person (excluding any executive benefit plan (or related
trust) maintained or sponsored by the Company or by the Acquiring Corporation) beneficially owns,
directly or indirectly, 50% or more of the combined voting power of the then-outstanding securities
of such corporation entitled to vote generally in the election of directors (except to the extent
that such ownership existed prior to the Business Combination); or

(d) the liquidation or dissolution of the Company.

Notwithstanding this Section 20.3, any change in ownership of the outstanding capital stock of
the Company that results from the acquisition of additional shares by Chiesi Farmaceutici SpA or
any of its affiliates (including any “going private” transaction whereby Chiesi Farmaceutici SpA
would acquire all of the outstanding capital stock of the Company not then owned by them),or
changes in Board composition resulting from the exercise by Chiesi Farmaceutici SpA and its
affiliates of voting power as majority stockholder(s) of the Company, shall not constitute a
“Change of Control” within the context of this Agreement.

20.4. For purposes of this Agreement, a “Change of Control Period” shall consist of
the period from three (3) months before until three (3) months after the date on which a Change of
Control occurs.

20.5. As used in this Agreement, the term “Disability” means, with respect to the
Executive, that the Executive is unable to perform the essential functions of his position with a
reasonable accommodation if necessary by reason of any medically determinable physical or mental
impairment. A determination of Disability shall be agreed upon by a physician satisfactory to the
Executive and a physician selected by the Company, provided that if these
physicians do not agree, the Executive and the Company shall each select a physician and these two
together shall select a third physician, whose determination as to Disability shall be binding on
all parties.

20.6. As used in this Agreement, the term “Exchange Act” shall mean the Securities
Exchange Act of 1934, as amended.

20.7. For purposes of this Agreement, “Good Reason” shall be deemed to exist upon
(a) any material reduction in the annual base compensation payable to the Executive (but exclusive
of any Target Cash Bonus, annual equity award or other similar cash bonus or equity plans for this
purpose); (b) the relocation of the place of business at which the Executive is principally located
to a location that is greater than thirty (30) miles from its current location; (c) the failure of
the Company to comply with a material term of this Agreement; (d) a material reduction in the
Executive’s level of responsibility to that which is not consistent with the position held by the
Executive, as defined in Section 2 herein, so long as notice of the Good Reason condition is given
within thirty (30) days of the condition’s initial existence, the Company is given thirty (30) days
to remedy the condition, and the termination from employment occurs within ninety (90) days
following the initial existence of one or more Good Reason conditions; (e) the Company’s shares
cease to be publicly traded at a time when Chiesi Farmaceutici SpA and its affiliates do not own at
least fifty percent (50%) of the outstanding shares of the Company; or (f) the Company’s shares are
delisted from or by Nasdaq at a time when Chiesi Farmaceutici SpA and its affiliates do not own at
least fifty percent (50%) of the outstanding shares of the Company. By way of clarification,
neither (I) any change in ownership of the outstanding capital stock of the Company that results
from the acquisition of shares by Chiesi Farmaceutici SpA or any of its affiliates, including but
not limited to, the fact that the Company is no longer registered pursuant to Section 12 of the
Securities Act of 1933, as amended, nor (II) the Company’s action to seek suspension of its
reporting obligations under Section 15(d) of the Exchange Act (i.e., “going dark”), shall of itself
constitute a “Good Reason” within the context of this Agreement.

20.8. For purposes of this Agreement, “pro rata payment” shall be deemed to mean the
calculation of a payment by the Company based on the proportion of the calendar year completed,
based on the nearest whole number of months of the Executive’s employment (for illustrative
purposes only, if the Executive was terminated without Cause by the Company on April
13th of a given year, the Executive would be entitled to 1/4 of his Target Cash Bonus
for such year under Section 5.4(d).

21. Non-Disparagement. The Executive understands and agrees that as a condition to
him of the monetary consideration provided in connection with this Agreement, during the term of
the Agreement and after the termination of his employment with the Company for any reason, he shall
not make any false, disparaging or derogatory statements in public or private to any person or
media outlet regarding the Company or any of its directors, officers, employees, agents, or
representatives or the Company’s business affairs and financial condition. The Company understands
and agrees that during the term of the Agreement and after the termination of the Executive’s
employment with the Company for any reason, the Company shall not make any false, disparaging or
derogatory statements in public or private to any person or media outlet regarding the Executive.
Nothing in this Section shall prohibit either Party from communicating or testifying truthfully (i)
to the extent required or protected by law, (ii) to any federal, state, or local governmental
agency, or (iii) in response to a subpoena to testify issued by a court of competent jurisdiction.

22. Section 409A. 

22.1. Parties’ Intent. The parties intend that the provisions of this Agreement
comply with the provisions of Section 409A and all provisions of this Agreement shall be construed
in a manner consistent with the requirements for avoiding taxes or penalties under Section 409A.
If any provision of this Agreement (or of any award of compensation, including equity compensation
or benefits) would cause the Executive to incur any additional tax or interest under Section 409A,
the Company shall, upon the specific request of the Executive, use its reasonable business efforts
to in good faith reform such provision to comply with Section 409A; provided, that to the maximum
extent practicable, the original intent and economic benefit to the Executive and the Company of
the applicable provision shall be maintained, and the Company shall have no obligation to make any
changes that could create any additional economic cost or loss of benefit to the Company. The
Company shall timely use its reasonable business efforts to amend any plan or program in which the
Executive participates to bring it in compliance with Section 409A. Notwithstanding the foregoing,
the Company shall have no liability with regard to any failure to comply with Section 409A so long
as it has acted in good faith with regard to compliance therewith.

22.2. Separation from Service. A termination of employment shall not be deemed to
have occurred for purposes of any provision of this Agreement providing for the payment of any
amounts or benefits upon or following a termination of employment unless such termination also
constitutes a “Separation from Service” within the meaning of Section 409A and, for purposes of any
such provision of this Agreement, references to a “termination,” “termination of employment,”
“separation from service” or like terms shall mean Separation from Service.

22.3. Separate Payments. Each installment payment required under this Agreement shall
be considered a separate payment for purposes of Section 409A.

22.4. Delayed Distribution to Key Employees. If the Company determines in accordance
with Sections 409A and 416(i) of the Code and the regulations promulgated thereunder, in the
Company’s sole discretion, that the Executive is a Key Employee of the Company on the date the
Executive’s employment with the Company terminates and that a delay in benefits provided under this
Agreement is necessary to comply with Code Section 409A(A)(2)(B)(i), then any severance payments
and any continuation of benefits or reimbursement of benefit costs provided by this Agreement, and
not otherwise exempt from Section 409A, shall be delayed for a period of six (6) months following
the date of termination of the Executive’s employment (the “409A Delay Period”). In such
event, any severance payments and the cost of any continuation of benefits provided under this
Agreement that would otherwise be due and payable to the Executive during the 409A Delay Period
shall be paid to the Executive in a lump sum cash amount in the month following the end of the 409A
Delay Period. For purposes of this Agreement, “Key Employee” shall mean an employee who,
on an Identification Date (“Identification Date” shall mean each December 31) is a key
employee as defined in Section 416(i) of the Code without regard to paragraph (5) thereof. If the
Executive is identified as a Key Employee on an Identification Date, then the Executive shall be
considered a Key Employee for purposes of this Agreement during the period beginning on the first
April 1 following the Identification Date and ending on the following March 31.

23. Parachutes. If all, or any portion, of the payments provided under this
Agreement, either alone or together with other payments and benefits which the Executive receives
or is entitled to receive from the Company or an affiliate, would constitute an excess “parachute
payment” within the meaning of Section 280G of the Code, the payments and benefits provided under
this Agreement shall be reduced to the extent necessary so that no portion thereof shall fail to be
tax-deductible under Section 280G of the Code.

[Remainder of this page is intentionally left blank]

SIGNATURE PAGE TO EXECUTIVE EMPLOYMENT AGREEMENT

IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the day and year set
forth above.

CORNERSTONE THERAPEUTICS INC.

By: /s/ Craig A. Collard—

Name: Craig A. Collard

Title: Chief Executive Officer

EXECUTIVE

By:      /s/ Kenneth R. McBean      

	 	 	Kenneth R. McBean

Appendix A

	 	1.	 	Shares of restricted stock awarded pursuant to Section 3.3 will be subject to the terms
of the Company’s Restricted Stock Agreement and will vest over 4 years as follows:

	 	a.	 	25% of the total award will vest on the first anniversary of the Effective Date;

	 	b.	 	A further 6.3% of the total award will vest on a day to be randomly determined in each
of the next 11 calendar quarters (provided that in no event shall the days so chosen in two
consecutive calendar quarters be less than 60 days apart from each other) following the
first anniversary of the award; and

	 	c.	 	The remainder of the total award will vest on the fourth anniversary of the Effective
Date.

d. If Chiesi Farmaceutici SpA or any of its affiliates makes a tender offer for all shares of
the Company or otherwise engages in any Business Combination in which Chiesi Farmaceutici SpA or
any of its affiliates would acquire all of the outstanding capital stock of the Company not then
owned by them, then any unvested restricted shares would be converted into an amount equal to
the cash consideration in the tender offer or other Business Combination with respect to such
number of unvested shares, which amount would vest and be paid to the Executive according to the
original vesting schedule through the fourth anniversary of the Effective Date . For example,
if the closing of a Business Combination with Chiesi Farmaceutici SpA occurred on the first
anniversary of Effective Date, 75% of the total award would be converted into restricted cash.
The restricted cash would vest and be paid on a quarterly basis during the remaining three years
of the vesting period.

2. Options to acquire common stock awarded pursuant to Section 3.3 will be subject to the terms of
the Company’s Stock Option Agreement and will vest over 4 years as follows:

a. 25% of the total award will vest on the first anniversary of the Effective Date;

b. An additional 2.09% of the total award will vest at the beginning of each of the next
thirty-five months following the first anniversary of the Effective Date and the remainder of
the total award will vest on the fourth anniversary of the Effective Date.

All rights of exercise shall be cumulative so that to the extent the option is not exercised in any
period to the maximum extent permissible it shall continue to be exercisable, in whole or in part,
with respect to all shares for which the option is vested until the earlier of the final exercise
date or the termination of the option.LGI-9.6.2011-EX4.1

Exhibit 4.1
€200,000,000 Additional Facility AA3 Accession Agreement
		
	To:
	The Bank of Nova Scotia as Facility Agent and  Security Agent

		
	From:
	The persons listed in Schedule 1 to this Additional Facility AA3 Accession Agreement (the Additional Facility AA3 Lenders)

Date:                    6 September 2011
UPC Broadband Holding B.V. (formerly known as UPC Distribution Holding B.V) - €1,072,000,000 Term Credit Agreement dated 16 January 2004 as amended from time to time (the Credit Agreement)
		
	1.
	In this Additional Facility AA3 Accession Agreement:

Additional Facility AA Accession Agreement means the €413,700,000 Additional Facility Accession Agreement dated 26 July 2011 entered into between, amongst others, UPC Broadband Operations B.V., as original lender, UPC Financing, as borrower and The Bank of Nova Scotia, as facility agent, as upsized pursuant to an Additional Facility Accession Agreement dated 2 August 2011.
Existing Facility AA means the €704,000,000 redrawable term loan facility made available under the Additional Facility AA Accession Agreement.
Existing Facility AA Advance means the outstanding Advance under the Existing Facility AA, as at the date of this Agreement, being €62,133,319.23.
Existing Facility AA Interest Period means the Interest Period currently selected (as at the date of this Agreement) in respect of the outstanding €62,133,319.23 Advance under Existing Facility AA.
Facility AA3 means the €200,000,000 redrawable term loan facility made available under this Agreement.
Facility AA3 Advance means a euro denominated advance made to UPC Financing by the Additional Facility AA3 Lenders under Facility AA3.
Facility AA3 Commitment means, in relation to an Additional Facility AA3 Lender, the amount in euros set opposite its name under the heading "Facility AA3 Commitment" in Schedule 1 to the counterpart of this Agreement executed by that Additional Facility AA3 Lender, to the extent not cancelled, transferred, or reduced under the Credit Agreement.
		
	2.
	Unless otherwise defined in this Additional Facility AA3 Accession Agreement, terms defined in the Credit Agreement shall have the same meaning in this Additional Facility AA3 Accession Agreement and a reference to a Clause is a reference to a Clause of the Credit Agreement.  The principles of construction set out in Clause 1.2 (Construction) of the Credit Agreement apply to this Agreement as though they were set out in full in this Additional Facility AA3 Accession Agreement.

		
	3.
	We refer to Clause 2.2 (Additional Facilities) of the Credit Agreement.

		
	4.
	This Additional Facility AA3 Accession Agreement will take effect on the date on which the 

Facility Agent notifies UPC Broadband and the Additional Facility AA3 Lenders that it has received the documents and evidence set out in Schedule 2 to this Additional Facility AA3 Accession Agreement, in each case in form and substance satisfactory to it or, as the case may be, the requirement to provide any of such documents or evidence has been waived by the Facility Agent on behalf of the Additional Facility AA3 Lenders (the Effective Date).
		
	5.
	We, the Additional Facility AA3 Lenders, agree: 

		
	(a)
	to become party to and to be bound by the terms of the Credit Agreement as Lenders in accordance with Clause 2.2 (Additional Facilities) of the Credit Agreement; and 

		
	(b)
	to become party to the Security Deed as Lenders and to observe, perform and be bound by the terms and provisions of the Security Deed in the capacity of Lenders in accordance with Clause 9.3 (Transfers by Lenders) of the Security Deed.

		
	6.
	The Additional Facility Commitment in relation to an Additional Facility AA3 Lender (for the purpose of the definition of Additional Facility Commitment in Clause 1.1 (Definitions) of the Credit Agreement) is its Facility AA3 Commitment.

		
	7.
	Any interest due in relation to Facility AA3 will be payable on the last day of each Interest Period in accordance with Clause 8 (Interest) of the Credit Agreement.

		
	8.
	The Additional Facility Availability Period for Facility AA3 shall be the period from and including the Effective Date up to and including the date falling one month before the Final Maturity Date in respect of Facility AA3.

		
	9.
	Facility AA3 shall comprise a committed term loan facility which shall (subject to paragraph 10 below) be capable of being reborrowed in relation to any sums that are prepaid in accordance with Clause 7.10(d) (Miscellaneous provisions) of the Credit Agreement.

		
	10.
	UPC Financing shall not deliver a Request in relation to Facility AA3 if as a result of the proposed Request more than 10 Advances under Facility AA3 would be outstanding.

		
	11.
	The Facility AA3 Advances will be used for general corporate purposes and working capital purposes, including the repayment or prepayment of existing indebtedness.

		
	12.
	(a)    The first Interest Period to apply to the first Facility AA3 Advance will be a period equal to the period running from the Effective Date up to and including the last day of the Existing Facility AA Interest Period.

		
	(b)
	In respect of the first Interest Period only, EURIBOR shall mean the EURIBOR rate as determined in respect of the Existing Facility AA Interest Period.

		
	13.
	The Final Maturity Date in respect of this Facility AA3 will be 31 July 2016.

		
	14.
	The outstanding Facility AA3 Advances will be repaid in full on the Final Maturity Date.

		
	15.
	The Margin in relation to Facility AA3 is 3.25 per cent. per annum.

		
	16.
	The Borrower in relation to Facility AA3 is UPC Financing.

		
	17.
	The Borrower shall pay to the Facility Agent for distribution to each Additional Facility AA3 Lender in accordance with Clause 20.1(b) (Commitment fee) of the Credit Agreement a commitment fee in an amount equal to 1.30 per cent. per annum of the undrawn uncancelled 

portion of the aggregate of the Facility AA3 Commitments.  Such commitment fee shall be calculated and shall accrue on a daily basis and shall be payable on the Effective Date and thereafter quarterly in arrears.
		
	18.
	(a)    It is the intention of the parties that Existing Facility AA be upsized by the amount of the Facility AA3 in accordance with this paragraph 18 and the terms of the existing Additional Facility AA Accession Agreement under which the Existing Facility AA is made available and that, on and from the Effective Date:

		
	(i)
	each Facility AA3 Advance will be consolidated with all amounts outstanding under the Existing Facility AA Advance; and

		
	(ii)
	Facility AA3 and Existing Facility AA shall constitute, and be considered as, a single Additional Facility under the Credit Agreement (being Additional Facility AA)

		
	(b)
	Provided that any upsizing of Facility AA3 permitted under this paragraph will not breach any term of the Credit Agreement, Facility AA3 may be upsized by any amount, by the signing of one or more further Additional Facility AA Accession Agreements, that specify (along with the other terms specified therein) UPC Financing as the sole Borrower and which specify Additional Facility Commitments denominated in euros, to be drawn in euros, with the same Final Maturity Date, Commitment Fee and Margin as specified in this Additional Facility AA3 Accession Agreement.

		
	(c)
	For the purposes of this paragraph 18 (unless otherwise specified), references to Additional Facility AA3 Lenders and Facility AA3 Advances shall include Lenders and Advances made under any such further and previous Additional Facility AA Accession Agreement.

		
	(d)
	Where any Existing Facility AA Advance has not already been consolidated with any other Existing Facility AA Advance, on the last day of any Interest Period for such Existing Facility AA Advance, that Existing Facility AA Advance will be consolidated with any other Existing Facility AA Advance which has an Interest Period ending on the same day as that Existing Facility AA Advance, and all such Existing Facility AA Advances will then be treated as one Advance.

		
	19.
	Each of UPC Broadband and UPC Financing confirms, on behalf of themselves and each other Obligor that the representations and warranties set out in Clause 15 (Representations and Warranties) of the Credit Agreement (with the exception of Clauses 15.6(a) (Consents), 15.10 (Financial condition), 15.12 (Security Interests), 15.13(b) (Litigation and insolvency proceedings), 15.14 (Business Plan), 15.15 (Tax liabilities), 15.16 (Ownership of assets), 15.18 (Works Council), 15.19 (Borrower Group Structure), 15.20 (ERISA), 15.24 (UPC Financing) and 15.25 (Dutch Banking Act)) are true and correct as if made at the Effective Date with reference to the facts and circumstances then existing, and as if each reference to the Finance Documents includes a reference to this Additional Facility AA3 Accession Agreement.

		
	20.
	UPC Broadband further represents and warrants on the Effective Date that the execution and delivery by it of this Additional Facility AA3 Accession Agreement and the performance of the transactions contemplated by this Additional Facility AA3 Accession Agreement will not violate any agreement or instrument to which UPC Holding is a party or binding upon UPC Holding or any member of the Borrower Group or any assets of UPC Holding or any member of the Borrower Group's assets, where such violation would or is reasonably likely to have a Material Adverse Effect.

		
	21.
	Each Additional Facility AA3 Lender confirms to each Finance Party that:

		
	(a)
	it has made its own independent investigation and assessment of the financial condition and affairs of each Obligor and its related entities in connection with its participation in the Credit Agreement and has not relied on any information provided to it by a Finance Party in connection with any Finance Document; and

		
	(b)
	it will continue to make its own independent appraisal of the creditworthiness of each Obligor and its related entities while any amount is or may be outstanding under the Credit Agreement or any Additional Facility Commitment is in force.

		
	22.
	Each of the Additional Facility AA3 Lenders agrees that without prejudice to Clause 26.3 (Procedure for novations) of the Credit Agreement, each New Lender (as defined in the Novation Certificate referred to below) shall become, by the execution by the Facility Agent of a Novation Certificate substantially in the form of part 1 or part 2 of Schedule 3 to this Additional Facility AA3 Accession Agreement, bound by the terms of this Additional Facility AA3 Accession Agreement as if it were an original party hereto as an Additional Facility AA3 Lender and shall acquire the same rights and assume the same obligations towards the other parties to this Additional Facility AA3 Accession Agreement as would have been acquired and assumed had the New Lender been an original party to this Additional Facility AA3 Accession Agreement as an Additional Facility AA3 Lender.

		
	23.
	The prior consent of UPC Broadband is required for any such assignment, transfer or novation (unless to an Additional Facility AA3 Lender or an Affiliate of an Additional Facility AA3 Lender), provided that:

		
	(a)
	UPC Broadband’s consent must not be unreasonably withheld or delayed;

		
	(b)
	the consent of UPC Broadband to an assignment, transfer or novation must not be withheld solely because the assignment, novation or transfer may result in an increase to the Mandatory Cost or the Sterling Mandatory Cost;

		
	(c)
	the prior consent of UPC Broadband is not required when an Event of Default is outstanding;

		
	(d)
	nothing in this paragraph 23 restricts the ability of any Additional Facility AA3 Lender to enter into any sub-participation or other arrangement with any third party relating to the Finance Documents which does not transfer to that third party any obligation and/or legal or equitable interest in any of the rights arising under the Credit Agreement.

		
	24.
	The Facility Office and address for notices of each Additional Facility AA3 Lender for the purposes of Clause 32.2 (Addresses for notices) of the Credit Agreement will be that notified by each Additional Facility AA3 Lender to the Facility Agent.

		
	25.
	This Additional Facility AA3 Accession Agreement and any non-contractual obligations arising out of or in connection with it are governed by English law.

		
	26.
	This Additional Facility AA3 Accession Agreement may be executed in any number of counterparts, and by each party on separate counterparts.  Each counterpart is an original, but all counterparts shall together constitute one and the same instrument.  Delivery of an executed counterpart signature page of this Additional Facility AA3 Accession Agreement by e-mail (PDF) or telecopy shall be as effective as delivery of a manually executed counterpart of this Additional Facility AA3 Accession Agreement.  

		
	Schedule 1
	

ADDITIONAL FACILITY AA3 LENDERS AND COMMITMENTS

	
		
	Additional Facility AA3 Lender
	Facility AA3 Commitment (€)

	UPC Broadband Operations B.V.
	200,000,000

	 
	 

	Total
	200,000,000

		
	Schedule 2
	

Conditions precedent documents
		
	1.
	Constitutional Documents

		
	(a)
	A copy of the constitutional documents of each Obligor (other than UPC Financing) and the partnership agreement of UPC Financing or, if the Facility Agent already has a copy, a certificate of an authorised signatory of the relevant Obligor confirming that the copy in the Facility Agent's possession is still correct, complete and in full force and effect as at a date no earlier than the date of this Additional Facility AA3 Accession Agreement.

		
	(b)
	An extract of the registration of each Obligor established in the Netherlands in the trade register of the Dutch Chamber of Commerce.

		
	2.
	Authorisations

		
	(a)
	A copy of a resolution of the board of managing directors and, to the extent applicable, board of supervisory directors (or equivalent) and, to the extent that a shareholders' resolution is required, a copy of the shareholders' resolution of each Obligor:

		
	(i)
	approving the terms of and the transactions contemplated by this Additional Facility AA3 Accession Agreement and (in the case of each of UPC Broadband and UPC Financing) resolving that it execute the same (and, in the case of the Guarantors and the Charging Entities (as defined in the Security Deed) resolving that it execute the confirmation described at paragraph 4(a) below; and

		
	(ii)
	(in the case of UPC Broadband and UPC Financing) authorising the issuance of a power of attorney to a specified person or persons to execute this Additional Facility AA3 Accession Agreement on its behalf and (in the case of the Guarantors and the Charging Entities (as defined in the Security Deed)) authorising the issuance of a power of attorney to a specified person or persons to execute the confirmation described in paragraph 4(a) below.

		
	(b)
	A specimen of the signature of each person authorised pursuant to its constitutional documents or to the power of attorney referred to in paragraph (a) above to sign this Additional Facility AA3 Accession Agreement or the confirmation described in paragraph 4(a) below (as appropriate).

		
	(c)
	A certificate of an authorised signatory of UPC Broadband, each Guarantor and each Charging Entity certifying that each copy document specified in this Schedule and supplied by UPC Broadband, each Guarantor and each Charging Entity is correct, complete and in full force and effect as at a date no earlier than the date of this Additional Facility AA3 Accession Agreement.

		
	(d)
	A copy of any other authorisation or other document, opinion or assurance which the Facility Agent has notified UPC Broadband is necessary in connection with the entry into and performance of, and the transactions contemplated by, this Additional Facility AA3 Accession Agreement or for the validity and enforceability of this Additional Facility AA3 Accession Agreement.

		
	3.
	Legal opinions

		
	(a)
	A legal opinion of Allen & Overy LLP, English legal advisers to the Facility Agent, addressed to the Finance Parties.

		
	(b)
	A legal opinion of Allen & Overy LLP, Dutch legal advisers to the Facility Agent, addressed to the Finance Parties.

		
	(c)
	A legal opinion of Allen & Overy LLP, New York legal advisers to the Facility Agent, addressed to the Finance Parties.

		
	4.
	Other documents

Confirmation (in writing) from (i) each of the Guarantors that its obligations under Clause 14 (Guarantee) of the Credit Agreement and (ii) each of the Charging Entities (as defined in the Security Deed) that the Security Interests granted to the Beneficiaries pursuant to the Security Documents and its obligations under the Finance Documents, shall continue unaffected and that such obligations extend to the Total Commitments as increased by the addition of Facility AA3 and that such obligations shall be owed to each Finance Party including the Additional Facility AA3 Lenders.

SCHEDULE 3
NOVATION CERTIFICATES
PART 1
NOVATION CERTIFICATE (CASH)

To:    The Bank of Nova Scotia as Facility Agent and UPC Financing as Borrower
From:    UPC Broadband Operations B.V. and [the EXISTING [●] LENDER / NEW AA3 LENDER]

Date:         2011
UPC Broadband Holding B.V. - ε1,072,000,000 Term Credit Agreement dated 16 January 2004 (the Credit Agreement)
We refer to: 
		
	(a)
	Clause 26.3 (Procedure for novations) of the Credit Agreement;

		
	(b)
	Clause 9.3 (Transfers by the Lenders) of the Security Deed; and

		
	(c)
	the Additional Facility AA3 Accession Agreement.

Terms defined in the Credit Agreement or, if not defined in the Credit Agreement, the Additional Facility AA3 Accession Agreements, have the same meaning in this Novation Certificate.
		
	1.
	UPC Broadband Operations B.V. (the Existing AA3 Lender) agrees to novate and [        ] (the New AA3 Lender) agrees to accept the novation on the Effective Date of all the Existing AA3 Lender's rights and obligations referred to in the Schedule in accordance with Clause 26.3 (Procedure for novations) of the Credit Agreement and clause 9.3 (Transfers by the Lenders) of the Security Deed.

		
	2.
	The New AA3 Lender confirms that it is bound by the terms of the Additional Facility AA3 Accession Agreement as if it were an original party thereto as an Additional Facility AA3 Lender and shall acquire the same rights and assume the same obligations towards the other parties to the Additional Facility AA3 Accession Agreement as would have been acquired and assumed had the New AA3 Lender been an original party to the Additional Facility AA3 Accession Agreement as an Additional Facility AA3 Lender.

		
	3.
	This certificate shall take effect on the date of this certificate.

		
	4.
	For the purposes of this certificate, “Effective Date” has the same meaning given to such term in the Additional Facility AA3 Accession Agreement.

		
	5.
	Each party to this document agrees, the Facility Agent agrees on behalf of each Finance Party, and UPC Broadband Holding B.V. agrees on behalf of each Obligor, that this document is a Novation Certificate notwithstanding that its form is different to that required by the Credit Agreement.

		
	6.
	This Novation Certificate is a Finance Document.

		
	7.
	This Novation Certificate may be executed in any number of counterparts, and by each party on separate counterparts.  Each counterpart is an original, but all counterparts shall together constitute one and the same instrument.  Delivery of an executed counterpart signature page of this Novation Certificate by e-mail (PDF) or telecopy shall be as effective as delivery of a manually executed counterpart of this Novation Certificate.

		
	8.
	This Novation Certificate and any non-contractual obligations arising out of or in connection with it are governed by English law.

THE SCHEDULE
Rights and obligations to be novated:

		
	27.
	Existing AA3 Lender

Existing AA3 Commitment: €[    ]
Assignee: New AA3 Lender

UPC BROADBAND OPERATIONS B.V., as the Existing AA3 Lender

By:
Name:
Title:

[THE NEW AA2 LENDER], as the New AA3 Lender

By:
Name:
Title:

UPC BROADBAND HOLDING B.V., as Obligors agent

By:
Name:
Title:

THE BANK OF NOVA SCOTIA, as Facility Agent

By:
Name:
Title:
The Facility Agent confirms that the Effective Date is the date on which it countersigns this Novation Certificate.

PART 2
NOVATION CERTIFICATE (CASHLESS)

To:    The Bank of Nova Scotia as Facility Agent and UPC Financing as Borrower
From:    UPC Broadband Operations B.V. and [the EXISTING [●] LENDER / NEW AA3 LENDER]

Date:         2011
UPC Broadband Holding B.V. - ε1,072,000,000 Term Credit Agreement dated 16 January 2004 (the Credit Agreement)
We refer to: 
		
	(a)
	Clause 26.3 (Procedure for novations) of the Credit Agreement;

		
	(b)
	Clause 9.3 (Transfers by the Lenders) of the Security Deed;

		
	(c)
	the Additional Facility [●] Accession Agreement; and

		
	(d)
	the €200,000,000 Additional Facility AA3 Accession Agreement.

Terms defined in the Credit Agreement or, if not defined in the Credit Agreement, the Additional Facility [●] Accession Agreements, have the same meaning in this Novation Certificate.
		
	9.
	[    ] (the Existing [●] Lender) agrees to novate and UPC Broadband Operations B.V. (the New [●] Lender) agrees to accept novation on the Effective Date, of all the Existing [●] Lender's rights and obligations referred to in the Schedule in accordance with Clause 26.3 (Procedure for novations) of the Credit Agreement and clause 9.3 (Transfers by the Lenders) of the Security Deed.

		
	10.
	UPC Broadband Operations B.V. (the Existing AA3 Lender) agrees to novate and [        ] (the New AA3 Lender) agrees to accept the novation on the Effective Date of all the Existing AA3 Lender's rights and obligations referred to in the Schedule in accordance with Clause 26.3 (Procedure for novations) of the Credit Agreement and clause 9.3 (Transfers by the Lenders) of the Security Deed.

		
	11.
	The New [●] Lender confirms that it is bound by the terms of the Additional Facility [●] Accession Agreement as if it were an original party thereto as an Additional Facility [●] Lender and shall acquire the same rights and assume the same obligations towards the other parties to the Additional Facility [●] Accession Agreement as would have been acquired and assumed had the New [●] Lender been an original party to the Additional Facility [●] Accession Agreement as an Additional Facility [●] Lender.

		
	12.
	The New AA3 Lender confirms that it is bound by the terms of the Additional Facility AA3 Accession Agreement as if it were an original party thereto as an Additional Facility AA3 Lender and shall acquire the same rights and assume the same obligations towards the other parties to the Additional Facility AA3 Accession Agreement as would have been acquired and assumed had the New AA3 Lender been an original party to the Additional Facility AA3 Accession Agreement as an Additional Facility AA3 Lender.

		
	13.
	This certificate shall take effect on the date of this certificate.

		
	14.
	For the purposes of this certificate, “Effective Date” has the same meaning given to such term in the Additional Facility AA Accession Agreement.

		
	15.
	Each party to this document agrees, the Facility Agent agrees on behalf of each Finance Party, and UPC Broadband Holding B.V. agrees on behalf of each Obligor, that this document is a Novation Certificate notwithstanding that its form is different to that required by the Credit Agreement.

		
	16.
	This Novation Certificate is a Finance Document.

		
	17.
	This Novation Certificate may be executed in any number of counterparts, and by each party on separate counterparts.  Each counterpart is an original, but all counterparts shall together constitute one and the same instrument.  Delivery of an executed counterpart signature page of this Novation Certificate by e-mail (PDF) or telecopy shall be as effective as delivery of a manually executed counterpart of this Novation Certificate.

		
	18.
	This Novation Certificate and any non-contractual obligations arising out of or in connection with it are governed by English law.

THE SCHEDULE
Rights and obligations to be novated:
		
	28.
	Existing [λ] Lender

Existing [●] Commitment: €[    ]
Assignee: New [●] Lender

		
	29.
	Existing AA3 Lender

Existing AA3 Commitment: €[    ]
Assignee: New AA3 Lender

[THE EXISTING [●] LENDER], as the Existing [λ] Lender

By:
Name:
Title:
UPC BROADBAND OPERATIONS B.V., as the New [●] Lender

By:
Name:
Title:

UPC BROADBAND OPERATIONS B.V., as the Existing AA3 Lender

By:
Name:
Title:

[THE NEW AA3 LENDER], as the New AA3 Lender

By:
Name:
Title:

UPC BROADBAND HOLDING B.V., as Obligors agent

By:
Name:
Title:

THE BANK OF NOVA SCOTIA, as Facility Agent

By:
Name:
Title:
The Facility Agent confirms that the Effective Date is the date on which it countersigns this Novation Certificate.

SIGNATORIES
THE BANK OF NOVA SCOTIA as Facility Agent
By:     Authorized Signatory

THE BANK OF NOVA SCOTIA as Security Agent
By:    Authorized Signatory

UPC BROADBAND HOLDING B.V.
By:     Authorized Signatory
By:    Authorized Signatory

UPC FINANCING PARTNERSHIP 
By:    Authorized Signatory
By:    Authorized Signatory

ADDITIONAL FACILITY AA3 LENDERS

UPC BROADBAND OPERATIONS B.V.
By: Authorized Signatory

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