Document:

Severance Agreement

 Exhibit 10.282 
 SEVERANCE AGREEMENT 
 THIS SEVERANCE AGREEMENT (the
“Agreement”), made as of the 16th day of
September, 2011, by and between Pharmaceutical Product Development, Inc. and its subsidiaries and affiliates (collectively, “PPD”) and Raymond H. Hill (“Employee”). 

WHEREAS, Employee and PPD entered into that certain Employment Agreement of even date herewith and, in connection therewith, PPD desires
to provide the severance benefits hereinafter described in the event of a “Change in Control”, as hereinafter defined, of PPD. 
 NOW, THEREFORE, it is agreed as follows: 
 1. Definitions

 1.01 “AFR” means the interest rate determined under Section 1274 of the Code. 

1.02 “Base Amount” shall have the meaning set forth and shall be determined as provided in Section 280G of the
Code. 
 1.03 “Change in Control” means (i) a change of control of a nature that would be required to be
reported in response to Item 6(e) of Schedule 14A of Regulation 14A promulgated under the Securities Exchange Act of 1934, as amended (“Exchange Act”), provided that such a Change in Control shall be deemed to have occurred if any
“person” (as such term is used in Sections 13(d) and 14(d)(2) of the Exchange Act) is or becomes the beneficial owner, directly or indirectly, of securities of PPD representing 50% or more of the combined voting power of PPD’s then
outstanding securities; (ii) a sale of substantially all of the assets of PPD; or (iii) a liquidation of PPD. 

1.04 “Constructive Termination” means a termination of Employee’s employment by PPD during the Covered Period
initiated by Employee after (i) a substantial diminution or alteration in the duties of Employee (it being understood that being CEO of the Company under different ownership or capital structure, or as a private company, is not a substantial
diminution or alteration in duties), (ii) a reduction by PPD in Employee’s base salary in effect on the date of the Change in Control, (iii) the relocation of Employee’s primary work location to a location that is more than
twenty-five (25) miles from Employee’s primary work location prior to the Change in Control or (iv) a material breach of the Employment Agreement of even date herewith between Employee and the Company. Constructive Termination
specifically does not include termination of Employee by reason of death, Disability or retirement at or after age 65. Employee shall give PPD written notice of a Constructive Termination, which notice shall provide a brief description of the
circumstances which Employee asserts gives rise to a right of Constructive Termination, and PPD shall have ten (10) days from receipt of said notice within which to remedy said circumstances. 

 1.05 “Covered Payment” means the amounts and benefits paid to Employee
pursuant to this Agreement, taken together with any amounts or benefits otherwise paid or distributed to Employee by PPD. 

1.06 “Covered Period” means the time period commencing on the date of and coincident with a Change of Control and ending
one year thereafter. 
 1.07 “Disability” means the inability of Employee to perform his assigned duties
for PPD with or without a reasonable accommodation for a period of three (3) months due to Employee’s physical or mental illness as determined by a reputable medical doctor. 

1.08 “Effective Date” means the date on which that certain Employment Agreement of even date herewith between PPD and
Employee becomes effective pursuant to the terms thereof. 
 1.09 “Excess Parachute Payment” shall have the
meaning set forth and shall be determined as provided in Section 280G of the Code. 
 1.10 “Excise Tax”
shall mean the tax imposed under Section 4999 of the Code on an Excess Parachute Payment. 
 1.11 “Executive
Consultant” shall mean the executive compensation or comparable consultant used from time to time by PPD in designing its compensation program for executive and senior management employees of PPD; provided, however, that in its sole
discretion PPD may at any time designate its independent auditors as its Executive Consultant for the purpose of performing any calculations required under Section 2.05 of this Agreement. 

1.12 “Final Determination” means a final determination by a court of competent jurisdiction or a proceeding of the
Internal Revenue Service or its successor agency. 
 1.13 “First Period” means the twelve-month period ending
on the Termination Date. 
 1.14 “Internal Revenue Code” means the Internal Revenue Code of 1986 as heretofore
or hereafter amended, and any successor code. References in this agreement to specific sections of the Code shall also include any successor sections. 
 1.15 “Parachute Payments” shall have the meaning set forth and shall be determined as provided in Section 280G of the Code. 

  
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 1.16 “Payment Cap” means the maximum amount which may be paid to Employee
under the terms of this Agreement without subjecting Employee to the Excise Tax. 
 1.17 “Payment Date” means
the date thirty (30) days following the Termination Date. 
 1.18 “Stock Awards” means Employee’s
outstanding awards of PPD non-qualified stock options or restricted stock as of the Termination Date. 
 1.19
“Termination for Cause” means (i) an act or acts involving fraud, embezzlement or theft from PPD, (ii) Employee’s willful and repeated failure to follow directions of the Board of Directors that continues for at least
ten (10) days following written notice of the Board of Directors of such failure to follow directions, or (iii) termination for cause as defined in and made pursuant to a then effective employment agreement, if any, between Employee and
PPD. 
 1.20 “Termination Date” means the date on which Employee’s employment is terminated such that
Employee is entitled to the compensation and benefits provided for in Section 2 of this Agreement. 
 2. Compensation
Upon Change of Control. This Agreement shall become effective on the Effective Date. If during the Covered Period (i) PPD terminates Employee’s employment for reason other than Termination for Cause or (ii) Employee’s
employment is terminated by reason of Constructive Termination, Employee shall, subject to signing a separation agreement and general release of claims in favor of the Company substantially in the form set out in attached Exhibit 1 to this
Agreement, modified as necessary so as to be fully enforceable under current applicable law, be entitled to the following compensation and benefits: 
 2.01 Base Salary and Bonus. PPD shall pay Employee an amount equal to two and ninety-nine one hundredths (2.99) times the sum of Employee’s (i) base salary for the First Period
(determined as if Employee was employed for the entire First Period if employed for less than the First Period) and (ii) the greater of (x) Employee’s target bonus under the PPD incentive cash bonus plan in which Employee is eligible
to participate immediately prior to the Termination Date or (y) the average of the cash bonuses received in the First Period and in the twelve-month period immediately preceding the First Period, said amount to be paid on the Payment Date.

 2.02 Unpaid and Deferred Compensation. PPD shall pay Employee any bonus or deferred compensation (whether in the form
of cash, stock or otherwise) accrued but unpaid as of the Termination Date, said sum to be paid on the Payment Date. 

  
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 2.03 Benefits. 

a. Group Term Life and AD&D Insurance. PPD shall reimburse Employee for premiums if Employee elects
to port the group term life and accidental death and dismemberment insurance to an individual policy by returning the portability election forms to the insurance carrier within thirty (30) days from the
Termination Date. However, PPD’s reimbursement obligations under this subsection shall terminate if and when Employee becomes eligible after the Termination Date for similar coverage under another employer’s plan or 24 months from
termination whichever happens sooner. 
 b. Healthcare Coverage (Medical, Dental and Vision). For two (2) years
after the Termination Date, PPD shall make available to Employee coverage under the PPD healthcare plan (Medical, Dental and Vision) that covered the Employee immediately prior to the Termination Date, provided that Employee pays the full monthly
premium for each month of coverage in accordance with the procedures applicable to the payment of COBRA premiums as set forth in Code section 4980B and the regulations thereunder (“COBRA guidance”). For purposes of clarity, the two
(2) years of coverage will be provided under the PPD plan and includes the full period of coverage mandated by COBRA guidance, plus any additional period of coverage to provide a total of two (2) years of coverage. The full monthly premium
payable by the Employee for the PPD health plan shall be the COBRA premium in effect for each month (or an amount equal to what the COBRA premium would be if COBRA were still mandated for the period after the period of mandated COBRA) as determined
by PPD in accordance with COBRA guidance. Failure of Employee to pay the premium in a timely manner (as determined under COBRA guidance) shall result in permanent loss of coverage. In addition for so long as Employee pays the premium for healthcare
coverage, PPD shall pay him an amount equal to two (2) times the difference between the full COBRA premium and the amount that Employee would have paid for such coverage if Employee had the coverage as an employee of PPD (rather than as a
former employee). Payment of such amount shall be made quarterly, and such amount shall be fully taxable as compensation income subject to tax and other required withholdings. However, PPD’s obligations under this subsection shall terminate if
and when Employee becomes eligible after the Termination Date for substantially comparable coverage under another employer’s healthcare plan. 
 2.04 Stock Awards. Employee expressly understands that should a Change in Control occur within twelve months of the Effective Date, Employee will be required to contribute the Stock Awards to
effect any such transaction, and in such event Employee will not receive any consideration in respect thereof upon a termination of his employment during the Covered Period. In any other circumstance, notwithstanding anything to the contrary in any
agreement for Stock Awards, (i) all unvested shares underlying Stock Awards granted more than six months prior to the Termination Date shall become fully vested as of the Termination Date, and (ii) Employee shall continue to

  
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be treated under each award agreement evidencing a Stock Award as if Employee was an employee of PPD until the first to occur of (x) the third anniversary of the Termination Date, or
(y) the expiration of the exercise period provided for therein; provided, however, in the event of Employee’s death or his disability (as disability is defined in the award agreement) after the Termination Date, the time for exercise after
death or such disability prescribed in the award agreement shall apply. The provisions of this Section 2.04 shall also apply to any and all substitute awards for nonqualified stock options and restricted stock granted to Employee in exchange
for Stock Awards to which this section applies. 
 2.05 Limitation on Payments. 

a. Application of Section 2.05. If a Covered Payment hereunder would be an Excess Parachute Payment and would thereby
subject Employee to the Excise Tax, the provisions of this Section 2.05 shall apply to determine the amounts payable to Employee pursuant to this Agreement. 
 b. Calculation of Benefits. At least fifteen (15) days prior to the Payment Date, PPD shall notify Employee of the aggregate present value of all amounts and benefits to which Employee would
be entitled under this Agreement and any other plan, program or arrangement with PPD as of the Termination Date, together with the projected maximum payments, determined as of such Date of Termination, that could be paid without Employee being
subject to the Excise Tax. 
 c. Imposition of Payment Cap. If (i) the aggregate value of all amounts and benefits
to which Employee would be entitled under this Agreement and any other plan, program or arrangement with PPD exceeds the amount which can be paid to Employee without Employee incurring an Excise Tax and (ii) Employee would receive a greater net
after-tax amount (taking into account all applicable taxes payable by Employee, including an Excise Tax) by applying the limitation contained in this Section 2.05(c), then the amounts otherwise payable to Employee under this Section 2
shall be reduced to an amount equal to the Payment Cap. If Employee receives reduced payments and benefits hereunder, Employee shall have the right to designate which of the payments and benefits otherwise provided for in this Agreement that
Employee will receive in connection with the application of the Payment Cap. 
 d. Application of Code Section 280G.
The Executive Consultant shall determine whether any part of the Covered Payment will be subject to the Excise Tax and the amount of such Excise Tax. For purposes of such determination, the Executive Consultant shall take into consideration and
be guided by the following: 
 (i) such Covered Payment will be treated as Parachute Payments and all Parachute Payments
in excess of the Base Amount shall be treated as subject to the Excise Tax, unless and except to the extent that in the good faith judgment of the Executive Consultant, PPD has a reasonable basis to conclude that such Covered Payment, in whole or in
part, either do not constitute Parachute Payments or represent reasonable compensation for personal services actually rendered (within the meaning of Section 280G of the Code) in excess of the Base Amount, or such Parachute Payments are
otherwise not subject to the Excise Tax, and 

  
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 (ii) the value of any noncash benefits or any deferred payment or benefit shall be
determined by the Executive Consultant in accordance with the principles of Section 280G of the Code. 
 (e) Applicable
Tax Rates. For purposes of determining whether Employee would receive a greater net after-tax benefit if the amounts payable under this Agreement are reduced in accordance with Section 2.05(c), Employee shall be deemed to pay: 

(i) federal income taxes at the highest applicable marginal rate of federal income taxation for the calendar year in which the
first amounts are to be paid hereunder, and 
 (ii) any applicable state and local income taxes at the highest
applicable marginal rate of taxation for such calendar year, net of the maximum reduction in federal income taxes which could be obtained from the deduction of such state or local taxes if paid in such year; provided, however, that Employee may
request that such determination be made based on Employee’s individual tax circumstances, which shall govern such determination so long as Employee provides to the Executive Consultant such information and documents as the Executive Consultant
shall reasonably request to determine such individual circumstances. 
 (f) Adjustments in Respect to Payment Cap.

 (i) If Employee receives reduced payments and benefits under Section 2.05 or if Section 2.05 is determined
not to be applicable to Employee because the Executive Consultant concludes that Employee is not subject to any Excise Tax, and it is established pursuant to a Final Determination that, notwithstanding the good faith of Employee and PPD in applying
the terms of this Agreement, the aggregate Parachute Payments paid to Employee or for Employee’s benefit are in an amount that would result in Employee being subject to an Excise Tax and Employee would still be subject to the Payment Cap under
the provisions of Section 2.05(c), then the amount in excess of the Payment Cap shall be deemed for all purposes to be a loan to Employee made on the date of the receipt of such excess payment, which Employee shall have an obligation to repay
to PPD on demand, together with interest at the AFR, from the date of the payment hereunder to the date of repayment by Employee. 
 (ii) If Section 2.05 is not applied to reduce Employee’s entitlements under this Section 2 because the Executive Consultant determines that Employee would not receive a greater net
after-tax benefit by applying Section 2.05 and it is established pursuant to a Final Determination that, notwithstanding the good faith of Employee and PPD in applying the terms of this Agreement, Employee would have received a greater net
after-tax benefit by subjecting Employee’s payments and benefits 

  
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hereunder to the Payment Cap, then the aggregate Parachute Payments paid to Employee or for Employee’s benefit in excess of the Payment Cap shall be deemed for all purposes a loan to
Employee made on the date of receipt of such excess payments, which Employee shall have an obligation to repay to PPD on demand, together with interest at the AFR, from the date of payment hereunder to the date of repayment by Employee. 

(iii) If Employee receives reduced payments and benefits by reason of this Section 2.05 and it is established pursuant to a
Final Determination that Employee could have received a greater amount without exceeding the Payment Cap, then PPD shall promptly thereafter pay Employee the aggregate additional amount which could have been paid without exceeding the Payment Cap,
together with interest on such amount at the AFR, from the original payment due date to the date of actual payment by PPD. 

3. Miscellaneous. 
 3.01 Successor-in-Interest. PPD will require any successor (whether direct or indirect, by purchase, merger, consolidation or otherwise) to all or substantially all of the business and/or assets of
PPD, to expressly assume and agree to perform this Agreement in the same manner and to the same extent that PPD would be required to perform it if no succession had taken place. 

3.02 Binding Effect. This Agreement shall inure to the benefit of and be enforceable by Employee’s personal or legal
representatives, executives, administrators, successors, heirs, distributees, devisees and legatees. 
 3.03 Notice. For
purposes of this Agreement, notices and all other communications provided for in the Agreement shall be in writing and shall be given (i) by certified mail, return receipt requested, postage prepaid, (ii) by personal delivery or
(iii) by recognized overnight carrier, and shall be deemed received when actually received. Notices shall be addressed as follows: 
  

			
	If to PPD:	  	Pharmaceutical Product Development, Inc.
		  	929 North Front Street
		  	Wilmington, North Carolina 28401
		  	Attention: Executive Chairman
		
	If to Employee:	  	Raymond H. Hill
		  	929 North Front Street
		  	Wilmington, NC 28401

 Either party hereto may change the notice address by giving notice thereof in the manner provided for herein. 

3.04 Waiver. No waiver by either party hereto at any time of any breach by the other party hereto of, or compliance with, any
provision or condition of this 

  
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Agreement to be performed by such other party shall be deemed a subsequent waiver of the same or similar provisions or conditions. The failure of any party at any time to require performance by
any other party of any provision hereof or to resort to any remedy provided herein or at law or in equity shall in no way affect the right of such party to require such performance or to resort to such remedy at any time thereafter, nor shall the
waiver by any party of a breach of any of the provisions hereof be deemed to be a waiver of any subsequent breach of such provisions. No such waiver shall be effective unless in writing and signed by the party against whom such waiver is sought to
be enforced. 
 3.05 Entire Agreement. No agreements or representations, oral or otherwise, expressed or implied, with
respect to the subject matter hereof have been made by either party which are not set forth expressly in this agreement, and this Agreement supersedes and replaces in its entirety all prior agreements and representations, expressed, implied, oral or
otherwise, made by PPD to or with Employee with respect to the subject matter hereof. 
 3.06 Governing Law. This
Agreement shall be governed by and interpreted under the laws of the State of North Carolina. 
 3.07 Unenforceability.
The invalidity or unenforceability of any provision of this Agreement shall not affect the validity or enforceability of any other provision of this Agreement. 
 3.08 Counterparts. This Agreement may be executed in one or more counterparts, each of which shall be deemed an original but all of which together shall constitute one and the same instrument.

 3.09 Headings. Headings used in this Agreement are for convenience only and shall not be used to construe or interpret
this Agreement. 
 3.10 Enforcement by Employee. All legal expenses incurred by Employee in the successful enforcement of
any of the terms of this Agreement shall be paid by PPD. 
 3.11 409A. 

(a) It is intended that this Agreement and the payments hereunder will not be considered to constitute in whole or in part payments from
a nonqualified deferred compensation plan within the meaning of Code section 409A and the Treasury Regulations and guidance promulgated thereunder (collectively, “Section 409A”) and so will be exempt from the requirements of
Section 409A, and the Agreement shall be interpreted to that end to the fullest extent possible. However, in the event that any payment or benefit (or portion thereof) provided pursuant to this Agreement is nonetheless determined to be
paid from a nonqualified deferred compensation plan subject to Section 409A, the applicable terms of this Agreement shall be interpreted in a manner that complies with Section 409A to the fullest extent possible. 

  
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 (b) Any payment due under the Agreement of nonqualified deferred compensation within the
meaning of Section 409A that is payable on termination of employment (or similar term) shall be delayed until the Employee also has a “separation from service” within the meaning of Section 409A. 

(c) For purposes of Section 409A, the Employee’s right to receive any installment payments pursuant to this Agreement
(including payments under Section 2.02 hereof) shall be treated as a right to receive a series of separate and distinct payments. Further, if an amount to be paid to the Employee under the Agreement on account of his “separation from
service” while the Employee is a “specified employee” is an amount payable under a “nonqualified deferred compensation plan” (as those terms are defined under Section 409A), any such payments that would otherwise be
paid within 6 months after such separation from service shall not be paid until the first business day after the end of such six-month period, or, if earlier, within 15 days after the appointment of the personal representative or executor of the
Employee’s estate following his death, at which time such delayed payments shall be paid in a single payment without interest. 
 (d) With regard to any provision herein that provides for reimbursement of costs and expenses or in-kind benefits that are not excluded from the Employee’s taxable income, then except as permitted by
Section 409A (i) the right to reimbursement or in-kind benefits shall not be subject to liquidation or exchange for another benefit; (ii) the amount of expenses eligible for reimbursement, or in-kind benefits, provided during any
taxable year shall not affect the expenses eligible for reimbursement, or in-kind benefits to be provided, in any other taxable year, provided, that the foregoing clause (ii) shall not be violated with regard to expenses reimbursed under any
arrangement covered by Section 105(b) of the Code solely because such expenses are subject to a limit related to the period the arrangement is in effect; and (iii) such payments shall be made on or before the last day of the
Employee’s taxable year following the taxable year in which the expense was incurred. 
 IN WITNESS WHEREOF, the parties
have executed this Severance Agreement effective the date first hereinabove set forth. 
  

							
	Pharmaceutical Product Development, Inc.	 		  	Employee
				
	By:	 	 /s/ Fred N. Eshelman
	 		  	 /s/ Raymond H. Hill

	Name:	 	 Fred N. Eshelman
	 		  	Raymond H. Hill
	Title:	 	 Executive Chairman
	 		  	

  
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 EXHIBIT 1 

SEPARATION AGREEMENT AND 
 GENERAL RELEASE OF CLAIMS 
 THIS SEPARATION AGREEMENT AND GENERAL RELEASE
OF CLAIMS (the “Agreement”) is entered into as of the date last set out below by and between Pharmaceutical Product Development, Inc., a North Carolina corporation (the “Company”), with a mailing address for notice purposes of
929 North Front Street, Wilmington, North Carolina 28401, Attention: Executive Chairman of the Board, and Raymond H. Hill (“Employee”), an individual whose mailing address for notice purposes is 929 North Front Street, Wilmington, North
Carolina 28401. (The Company and Employee are sometimes referred to herein as each a “Party” and together as the “Parties.”) 
 RECITALS 
 A. Employee and the Company are parties to that certain
Severance Agreement, effective as of September 16, 2011 (the “Severance Agreement”); and 
 B. Employee’s
employment is being terminated [by the Company during the Covered Period for reason other than Termination for Cause pursuant to Section 2 of the Severance Agreement] [during the Covered Period by reason of Constructive Termination pursuant to
Section 2 of the Severance Agreement]; and 
 C. A condition to Employee’s receipt of certain payments
post-termination is the execution of this Agreement; and 
 D. Unless otherwise defined herein, capitalized terms not
specifically defined in this Agreement will have the same definition as provided in the Severance Agreement. 
 NOW, THEREFORE,
in consideration of the covenants and mutual promises contained herein, as well as the payment of certain consideration to Employee as hereinafter recited, the receipt and sufficiency of which are hereby acknowledged by Employee, it is agreed as
follows: 
 1. Termination. Employee’s employment with the Company is terminated effective as of [DATE] (the
“Termination Date”). Except as set out in this Agreement, as provided by the specific terms of a benefit plan or award (or similar) agreement or as required by law, upon the termination of Employee’s employment with the Company,
effective as of the Termination Date, all of Employee’s employee benefits with the Company will terminate. Employee hereby represents that he has returned to the Company all documents, records, apparatus, equipment and other physical property,
or any reproduction of such property, whether or not pertaining to Proprietary Information, furnished to Employee by the Company or produced by Employee or others in 

  
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connection with Employee’s employment; provided, however, that subject to the Company’s right to inspect and redact any Proprietary Information there from, Employee may retain
possession of his personal rolodex. Employee hereby acknowledges that, other than as provided in this Agreement, he has been paid all wages for labor or services rendered by him for the Company or on the Company’s behalf through the Termination
Date. 
 2. Compensation and Benefits. If Employee signs and does not revoke this Agreement as provided in
Section 10 below, the Company will provide Employee with the compensation and benefits described in Section 2 of the Severance Agreement (the “Severance Pay and Benefits”), upon the terms and conditions of payment as set out in
such Severance Agreement. 
 If Employee does not sign this Agreement and return it to the Company within [twenty-one (21)] [forty-five (45)]
days, or if Employee revokes it pursuant to Section 10, below, Employee will not be entitled to receive the Severance Pay and Benefits described above. 
 3. Release of Claims. In exchange for the Company’s providing Employee with the Severance Pay and Benefits described in Section 2, above, by signing this Agreement, Employee hereby
releases and forever discharges the Company, as well as its parent companies, affiliates, subsidiaries, divisions, officers, directors, stockholders, employees, agents, representatives, attorneys, lessors, lessees, licensors and licensees, and their
respective successors, assigns, heirs, executors and administrators (collectively, the “Company Parties”), from any and all claims, demands, and causes of action of every kind and nature, whether known or unknown, direct or indirect,
accrued, contingent or potential, which Employee ever had or now has, including but not limited to any claims arising out of or related to Employee’s employment with the Company and the termination thereof (except where and to the extent that
such a release is expressly prohibited or made void by law). This release includes, without limitation, Employee’s release of the Company and the Company Parties from any claims by Employee for lost wages or benefits, stock options, restricted
stock, compensatory damages, punitive damages, attorneys’ fees and costs, equitable relief or any other form of damages or relief. In addition, this release is meant to release the Company and the Company Parties from all common law claims,
including claims in contract or tort, including, without limitation, claims for breach of contract, wrongful or constructive discharge, intentional or negligent infliction of emotional distress, misrepresentation, tortious interference with contract
or prospective economic advantage, invasion of privacy, defamation, negligence or breach of any covenant of good faith and fair dealing. Employee also specifically and forever releases the Company and the Company Parties (except where and to the
extent that such a release is expressly prohibited or made void by law) from any claims based on unlawful employment discrimination or harassment , including, but not limited to, the Federal Age Discrimination in Employment Act (29 U.S.C. §
621 et. seq.). This release does not include Employee’s right to indemnification, and related insurance coverage, under Section 7.1.4 of the Employment Agreement, his right to equity awards, or continued exercise,
pursuant to the terms of any specific equity award (or similar) 

  
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agreement between Employee and the Company nor to Employee’s right to benefits under any Company plan or program in which Employee participated and is due a benefit in accordance with the
terms of the plan or program as of the date hereof. 
 Employee acknowledges that this release applies both to known and unknown claims that may
exist between Employee and the Company and the Company Parties. Employee expressly waives and relinquishes all rights and benefits that Employee may have under any state or federal statute or common law principle that would otherwise limit the
effect of this Agreement to claims known or suspected prior to the date Employee executes this Agreement, and does so understanding and acknowledging the significance and consequences of such specific waiver. In addition, Employee hereby expressly
understands and acknowledges that it is possible that unknown losses or claims exist or that present losses may have been underestimated in amount or severity, and Employee explicitly took that into account in giving this release. 

By signing this Agreement, Employee agrees and acknowledges that he has no cause to believe that any violation of any local, state or federal law that
has occurred with respect to his employment or separation of employment from the Company. Provided, however, that nothing in this Agreement extinguishes any claims Employee may have against the Company for breach of this Agreement. 

4. No Admissions. Employee understands, acknowledges and agrees that the release set out above in Section 3 is a final
compromise of any potential claims by Employee against the Company and/or the Company Parties in connection with his employment by the Company, and is not an admission by the Company or the Company Parties that any such claims exist or that the
Company or any of the Company Parties are liable for any such claims. To the greatest extent permitted by law, Employee further agrees not to hereafter, directly or indirectly, sue, assist in or be a voluntary party to any litigation against Company
or any one or more of the Company Parties for any claims relating to events occurring prior to or simultaneously with the execution of this Agreement, including but not limited to Employee’s termination of employment with the Company.

 Notwithstanding the foregoing, nothing in this Agreement prohibits Employee from filing a charge with, or participating in
any investigation or proceeding conducted by, the U.S. Equal Employment Opportunity Commission or a comparable state or federal fair employment practices agency; provided, however, that this Agreement fully and finally resolves all monetary matters
between Employee and the Company and the Company Parties, and by signing this Agreement, Employee is waiving any right to monetary damages, attorneys’ fees and/or costs related to or arising from any such charge, complaint or lawsuit filed by
Employee or on his behalf, individually or collectively. 
 5. Withholding Taxes. All amounts payable under this
Agreement, whether such payment is to be made in cash or other property, shall be subject to applicable withholding requirements for Federal, state and local income taxes, employment and payroll taxes, and other legally required withholding taxes
and contributions to the extent appropriate in the determination of the Company. 

  
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 6. Future Conduct. Employee agrees that he will not denigrate, defame, disparage or
cast aspersions upon the Company, the Company Parties, their products, services, business and manner of doing business, and that he will use his reasonable best efforts to prevent any member of his immediate family from engaging in any such
activity. The Company agrees that its Board of Directors and senior executives will not denigrate, defame, disparage or cast aspersions upon Employee, his services, business and manner of doing business. Employee further agrees that in exchange for
the Severance Pay and Benefits, during any period of time when Employee is receiving such Severance Pay and/or Benefits, Employee will make himself reasonably available to render, and to render at the request of the Company, services as are deemed
reasonably necessary by the Company to effect an orderly transition of Employee’s duties to other employees of the Company. In addition, Employee further agrees to provide reasonable assistance upon the request of the Company related to any
litigation in which he may be of assistance or in which his testimony is required. Executive shall be entitled to reasonable compensation and reimbursement of necessary expenses in rendering such assistance. Employee also hereby acknowledges and
agrees that his post-employment duties and obligations under the Proprietary Information and Inventions Agreement and the Non-Competition and Non-Solicitation Agreement signed in connection with his employment with the Company will remain in full
force and effect in accordance with their terms, and that any breach of such agreements will also constitute a breach of this present Agreement in accordance with Section 7 below. 

7. Relief and Enforcement. Employee understands and agrees that if he violate the terms of Section 6 of this Agreement, he
will cause injury to the Company (and/or one or more of the Company Parties) that will be difficult to quantify or repair, so that the Company (and/or the Company Parties) will have no adequate remedy at law. Accordingly, Employee agrees that if he
violates Sections 6 of this Agreement, the Company (or the Company Parties) will be entitled as a matter of right to obtain an injunction from a court of law, restraining Employee from any further violation of this Agreement. The right to an
injunction is in addition to, and not in lieu of, any other remedies that the Company (or the Company Parties) has at law or in equity. 
 8. No Modifications; Governing Law; Entire Agreement. This Agreement cannot be changed or terminated verbally, and no modification or waiver of any of the provisions of this Agreement will be
effective unless it is in writing and signed by both Parties. The Parties agree that this Agreement is to be governed by and construed in accordance with the laws of the State of North Carolina, and that any suit, action or charge arising out of or
relating to this Agreement will be adjudicated in the state or federal courts in Wake County, North Carolina. This Agreement sets forth the entire and fully integrated understanding between the Parties with respect to the subject matter hereof, and
there are no representations, warranties, covenants or understandings regarding the subject matter hereof, oral or otherwise, that are not expressly set out herein. 

  
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 9. Voluntary Execution. By signing below, Employee and the Company each acknowledge
that he has read this Agreement, that he understands its contents and that he has relied upon or had the opportunity to seek the legal advice of his attorney, who is the attorney of his own choosing. 

10. Right to Revoke. ONCE SIGNED BY EMPLOYEE, THIS AGREEMENT IS REVOCABLE IN WRITING FOR A PERIOD OF SEVEN (7) DAYS (THE
“REVOCATION PERIOD”). IN ORDER TO REVOKE HIS ACCEPTANCE OF THIS AGREEMENT, EMPLOYEE MUST DELIVER WRITTEN NOTICE TO [NAME], AND SUCH WRITTEN NOTICE MUST ACTUALLY BE RECEIVED WITHIN THE SEVEN (7) DAY REVOCATION PERIOD. 

11. Miscellaneous. 
 (a) Should any portion, term or provision of this Agreement be declared or determined by any court to be illegal, invalid or unenforceable, the validity or the remaining portions, terms and provisions
shall not be affected thereby, and the illegal, invalid or unenforceable portion, term or provision shall be deemed not to be part of this Agreement. 
 (b) The Parties agree that the failure of a Party at any time to require performance of any provision of this Agreement shall not affect, diminish, obviate or void in any way the Party’s full right
or ability to require performance of the same or any other provision of this Agreement at any time thereafter. 
 (c) This
Agreement shall inure to the benefit of and shall be binding upon Employee, his heirs, administrators, representatives, executors, successors and assigns and upon the successors and assigns of the Company. 

(d) The headings of the paragraphs of this Agreement are for convenience only and are not binding on any interpretation of this
Agreement. This Agreement may be executed in counterparts. 
 EMPLOYEE HEREBY ACKNOWLEDGES THAT HE HAS BEEN GIVEN A PERIOD OF AT LEAST
TWENTY-ONE (21) DAYS TO CONSIDER WHETHER TO EXECUTE THIS AGREEMENT. EMPLOYEE IS HEREBY ADVISED BY THE COMPANY IN WRITING TO CONSULT WITH AN ATTORNEY BEFORE SIGNING THIS AGREEMENT. 

  
 14 

 IN WITNESS WHEREOF, each of the Parties hereto has executed this Separation and Agreement
and General Release of Claims as of the date first above written. 
  

					
	PHARMACEUTICAL PRODUCT DEVELOPMENT, INC.
		
	By:	 	  

		
	Name:	 	  

		
	Title:	 	  

		
	Date:	 	
		
	EMPLOYEE	 	
		
	  
	 	(SEAL)
	Raymond H. Hill	 	
			
	Date:	 	  
	 	

  
 15Form of Executive Employment Agreement

 Exhibit 10.1 
 DENDREON CORPORATION 
 EXECUTIVE EMPLOYMENT AGREEMENT 

(WASHINGTON STATE) 
 This Executive Employment Agreement (this “Agreement”) is entered into as of the date of the last signature to this Agreement (“Effective Date”), by and
between Dendreon Corporation, a Delaware corporation (the “Company”), and [NAME] (“Employee”). 
 The parties agree as follows: 
 1. Employment. The Company hereby
employs Employee as [TITLE], and Employee hereby accepts such employment, upon the terms and conditions set forth in this Agreement. 
 2. Duties. 
 2.1 Position. Employee shall perform such
duties as are customary for the position of [TITLE] at companies of the Company’s size and nature in the United States and any additional duties that the [TITLE]’s immediate supervisor or the Board of Directors of the Company
(the “Board”) may reasonably prescribe from time to time and which are consistent with Employee’s position. Employee shall devote Employee’s full business time and efforts to the performance of Employee’s
assigned duties for the Company, provided, however, that Employee may devote reasonable periods of time to (a) serving on the board of directors of other corporations subject to the prior approval of the [CEO OR, IN THE CASE OF
THE CEO, THE BOARD], and (b) engaging in charitable or community service activities, so long as none of the foregoing additional activities materially interfere with Employee’s duties under this Agreement. 

2.2 Work Location. Employee’s principal place of work shall be located in Seattle, Washington, or such other location
as the parties may agree upon from time to time. 
 3. Term. The employment relationship pursuant to this
Agreement shall begin on the Effective Date, will be for no specified term, and may be terminated by Employee or the Company at any time, with or without Good Reason or Cause (as defined in Section 6), as applicable, subject to the provisions
regarding termination set forth in Section 6. 
 4. Compensation. 

4.1 Base Salary. As compensation for Employee’s performance of [his/her] duties under this Agreement, the
Company shall pay Employee a base salary (“Base Salary”), which shall initially equal [                    ] dollars
($[            ]) per calendar year, payable in accordance with the normal payroll practices of the Company, less required deductions for state and federal withholding tax, social security
and all other required employment taxes and payroll deductions. For purposes of Section 6 hereof, Employee’s Base Salary shall be the current Base Salary as of the date of [his/her] termination of employment (the

 
“Termination Date”). The Base Salary may not be reduced unless the base salaries of all other employees of the Company at the Vice President level and
above are proportionally reduced and in the case of such reduction, Base Salary shall not be reduced by more than 10%. 

4.2 Incentive Compensation. Within thirty (30) days after the end of each calendar year, if the Company and Employee
meet specified targets agreed upon in advance by the Board, Employee shall be entitled to receive a target bonus of [fifty – EVP] [one hundred – CEO] percent ([50 – EVP] [100 – CEO]%) of [his/her] Base Salary
(the “Annual Bonus”) as determined by the Board, in its sole discretion. Employee must be currently employed by the Company as of the date of payment of any Annual Bonus in order to be entitled to such payment. If the Company
and Employee do not fully meet such targets, the Company may pay Employee a bonus of such amount as the Board deems appropriate in its sole discretion. Before the beginning of a new bonus year, the Board may, in its discretion, reduce the percentage
of the Annual Bonus applicable to employees, provided that Employee’s Annual Bonus may be reduced only to the extent that the percentage annual bonuses of all other employees of the Company at the Vice President level and above are
proportionally reduced. 
 4.3 Equity Grants. Employee shall be entitled to annual grants of stock options,
restricted stock and other equity based long term incentive compensation generally made available to comparable senior executives of the Company on substantially the same terms and conditions as generally applicable to such other executives.

 4.4 Performance and Compensation Review. Employee’s performance will be reviewed no less frequently than
annually to determine whether Employee’s salary or other compensation should be modified. 
 4.5 Vacation.
Employee shall be eligible to earn four (4) calendar weeks of paid vacation in each year of this Agreement. Vacation will accrue at the rate of six and two-thirds (6 2/3) hours per pay period, and may be carried over from year to year up to a
maximum cap of 240 hours and in accordance with Company policy. Additional paid vacation shall accrue in accordance with Company policy. Any accrued unused vacation will be cashed out upon termination of employment at Employee’s then current
Base Salary rate in accordance with Company policy and applicable law. 
 4.6 Benefits and Insurance. In addition
to the vacation benefits in Section 4.5 above, Employee shall be entitled to all benefits that the Company may make generally available from time to time to its employees, subject to the terms and conditions of the applicable policy or plan,
and provided that Employee understands that he/she will be designated as a key employee for purposes of any leave granted under the Family and Medical Leave Act. 
 5. Business Expenses. The Company shall pay, or promptly reimburse, Employee for all reasonable, out-of-pocket travel and business expenses incurred in the performance of Employee’s
duties on behalf of the Company for which Employee submits the required supporting documentation and otherwise fully complies with the Company’s travel and expense reimbursement policy as in effect from time to time. Reimbursements under this
Section 5 will be made in accordance with Section 9.12. 

  
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 6. Separation of Employee’s Employment. 

6.1 Termination for Cause by the Company. The Company may terminate Employee’s employment at any time for Cause. For
purposes of this Agreement, “Cause” is defined as: (i) Employee’s willful and continued failure to substantially perform [his/her] duties and responsibilities, after prior written notice thereof and an
opportunity to cure; (ii) Employee’s willful engaging in conduct which is materially injurious (monetarily or otherwise) to the Company, including without limitation, misuse of Company funds or property; (iii) Employee’s
conviction of a felony (other than a moving vehicle violation); or (iv) any other material breach by Employee of this Agreement or any confidentiality, noncompetition, nondisclosure and/or invention agreement with the Company which is
materially injurious (monetarily or otherwise) to the Company. Notwithstanding the foregoing, the Company must notify Employee of any event constituting Cause within 45 days following the Company’s knowledge of its existence or such event will
not constitute Cause under this Agreement. For purposes of this Agreement, no act or failure to act, on the part of Employee, will be considered “willful” unless it is done, or omitted to be done, by Employee in bad faith or without
reasonable belief that Employee’s action or omission was in the best interests of the Company. Employee’s employment will in no event be considered to have been terminated by the Company for Cause if the act or failure to act upon which
such termination is based is an act or failure to act in respect of which Employee meets the applicable standard of conduct prescribed for indemnification or reimbursement or payment of expenses under the By-laws of the Company or the laws of the
state of its incorporation or the directors’ and officers’ liability insurance of the Company, in each case as in effect at the time of such act or failure to act. 
 In the event that Employee’s employment is terminated in accordance with this Section 6.1, Employee shall be entitled to receive, on Employee’s first regular payday following the Termination
Date, a lump sum payment equal to the following: (i) any portion of Employee’s Base Salary that has been earned but not yet paid as of the Termination Date, and (ii) any accrued unused vacation as of the Termination Date, all of the
foregoing to be less required withholding (clauses (i) and (ii) collectively, the “Accrued Benefits”). All other Company obligations to Employee, including but not limited to any bonus as described in
Section 4.2 and Severance (as defined in Section 6.2), will automatically terminate and be completely extinguished as of the Termination Date; provided, however, Employee shall continue to be entitled to any accrued benefits under the
Company’s benefit and welfare plans and to indemnification and continued coverage under the Company’s director and officer insurance policies (“D&O Policies”). 

6.2 Termination Without Cause; Change of Control. 

(a) If the Company terminates Employee’s employment without Cause, or if Employee resigns for Good Reason in accordance with
Section 6.3, then Employee will be entitled to receive the following: 
 (i) a lump sum severance payment in an amount
equal to [one hundred twenty five percent – EVP] [one hundred fifty percent – CEO] ([1.25x – EVP] [1.5x – CEO]) times Employee’s then current Base Salary and Employee’s target Annual Bonus in respect of
the calendar year in which the termination of employment occurs, less required withholding, and (ii) the amounts set forth in paragraph (c) below. 

  
 - 3 -

 (b) If the Company terminates Employee without Cause, or if Employee resigns for Good
Reason in accordance with Section 6.3, in either case within three (3) months before or twelve (12) months following a Change of Control, then Employee will be entitled to receive , the following (the “CIC Severance
Payment”): 
 (i) a lump sum severance payment in an amount equal to [one hundred fifty percent – EVP] [two
hundred percent – CEO] ([1.5x – EVP] [2.0x – CEO]) times the sum of Employee’s then current Base Salary (without regard to any reduction in Base Salary that would otherwise constitute Good Reason) and Employee’s
target Annual Bonus in respect of the calendar year in which the termination of employment occurs; provided, however, that the CIC Severance Payment will be reduced by any amount of payments received by Employee pursuant to Section 6.2(a)
above; and (ii) the amounts set forth in paragraph (c) below. 
 (c) In addition to those amounts set forth in
paragraphs (a) or (b) above, as applicable, Employee shall be entitled to (i) on Employee’s first regular payday following the Termination Date, a lump sum payment equivalent to the Accrued Benefits; (ii) reasonable costs
not to exceed $10,000 for outplacement services provided by a purveyor approved by the Company and moving expenses, upon delivery to the Company of an itemized invoice for such services provided that, in each case, such costs are incurred within six
(6) months of the Termination Date; (iii) continuation of all medical and dental benefits in effect on the Termination Date at no cost to the Employee, for a period of eighteen (18) months following the Termination Date, or until
Employee is eligible to receive comparable medical and dental benefits from another employer; provided, however, (A) Employee timely elects the continuation of group health plan benefits under the Consolidated Omnibus Budget Reconciliation Act
of 1985 (“COBRA”), (B) if the Company elects to provide continuation of medical and dental benefits on a reimbursement basis, Employee makes a payment to the Company in an amount equal to the monthly premium payments
(both the employee and employer portions) required to maintain such coverage with such reimbursement process in compliance with Section 9.12(c) of this Agreement, (D) Employee and the Company acknowledge that this coverage will count
towards the Company’s and the applicable group health plan’s obligation to provide Employee with the right to continuation coverage pursuant to COBRA and Employee will be able to continue such coverage at [his/her] own expense for
the balance of the period provided under COBRA, and (E) notwithstanding anything contained in this Agreement, Employee will not have a duty to mitigate the payments to be made to Employee pursuant to this Section 6.2(c) by obtaining
subsequent employment or otherwise; (iv) any unpaid Annual Bonus with respect to the calendar year ended prior to the termination of Employee’s employment; and (v) full accelerated vesting of any and all unvested stock options,
restricted stock units and restricted stock grants held by Employee. 
 (d) “Change of Control” shall mean the
occurrence, in a single transaction or in a series of related transactions, of one or more of the following events: 
 (i) Any
Person, as defined under the Securities Exchange Act of 1934, as amended (the “Exchange Act”) (“Person”), becomes the owner of voting securities

  
 - 4 -

 
of the Company (“Voting Securities”) representing more than fifty percent (50%) of the combined voting power of the Company’s then-outstanding securities, other
than by virtue of a merger, consolidation or similar transaction; provided, however, that in determining whether a Change of Control has occurred, Voting Securities which are acquired by any Person in a Non-Control Acquisition (as hereinafter
defined) shall not constitute an acquisition which would cause a Change of Control. A “Non-Control Acquisition” shall mean an acquisition by (A) an employee benefit plan (or a trust forming a part thereof) maintained by
(1) the Company or (2) any of the Company’s subsidiaries, (B) the Company or any of the Company’s subsidiaries, or (C) any Person of not more than 25% of the Voting Securities that is entitled to and does report such
beneficial ownership on Schedule 13G under the Exchange Act (a “13G Filer”), provided, however, that this clause (C) shall cease to apply when a Person who is a 13G Filer becomes required to file a Schedule 13D under the
Exchange Act with respect to such beneficial ownership of the Voting Securities; 
 (ii) The consummation of a merger,
consolidation or similar transaction that directly or indirectly involves the Company (a “transaction”), other than a transaction which results in (A) the Incumbent Directors (as hereinafter defined) constituting
immediately after such transaction at least a majority of the Board, the entity surviving such merger or consolidation or, if the Company or the entity surviving such merger is then a subsidiary, the ultimate parent thereof, and (B) the voting
securities of the Company outstanding immediately prior to such transaction continuing to represent (either by remaining outstanding or by being converted into voting securities of the surviving entity or any parent thereof), in combination with the
ownership of any trustee or other fiduciary holding securities under an employee benefit plan of the Company or any subsidiary of the Company, more than fifty percent (50%) of the combined voting power of the securities of the Company or such
surviving entity or any parent thereof outstanding immediately after such transaction; 
 (iii) The stockholders of the Company
approve, or the Board approves, a plan of complete dissolution or liquidation of the Company, or a complete dissolution or liquidation of the Company otherwise occurs; 
 (iv) The consummation of a sale, lease or other disposition of all or substantially all of the consolidated assets of the Company (a “disposition”) that requires approval of the
Company’s stockholders under Delaware corporate law; provided that this paragraph (d)(iv) excludes a disposition to an entity with respect to which stockholders of the Company own immediately after the disposition more than fifty percent
(50%) of the combined voting power of the entity’s outstanding voting securities; or 
 (v) The Board ceases to be
composed of at least a majority of Incumbent Directors. “Incumbent Directors” are the current members of the Board and any subsequent Board member who was nominated or elected by a majority vote of the Incumbent Directors
then in office; provided, however, that no individual shall be considered an Incumbent Director if such individual initially assumed office as a result of either an actual or threatened election contest or other actual or threatened solicitation of
proxies or consents by or on behalf of a Person other than the Board (a “Proxy Contest”) including by reason of any agreement intended to avoid or settle any election contest or Proxy Contest. 

  
 - 5 -

 Notwithstanding the above clauses (i) through (v), a “Change of Control”
shall not have occurred (unless the Board determines otherwise) by reason of either of the following: (A) any corporate reorganization, merger, consolidation, transfer of assets, liquidating distribution or other transaction entered into solely
by and between the Company and any subsidiary of the Company (a “reorganization”), provided the reorganization was approved by at least two-thirds (2/3) of the Incumbent Directors (as defined above) then in office and
voting; or (B) any of the transactions described in clauses (i) through (v) above occurs pursuant to an Insolvency Proceeding. An “Insolvency Proceeding” means (A) the Company institutes or consents to the
institution of any proceeding under any debtor relief law, makes an assignment for the benefit of creditors, or applies for or consents to the appointment of any receiver, trustee, custodian, conservator, liquidator, rehabilitator or similar officer
for the Company or for all or any material part of the Company’s property; or (B) any receiver, trustee, custodian, conservator, liquidator, rehabilitator or similar officer is appointed without the application or consent of the Company
and the appointment continues undischarged or unstayed for 60 calendar days; or (C) any proceeding under any debtor relief law relating to the Company or to all or any material part of the Company’s property is instituted without the
consent of the Company and continues undismissed or unstayed for 60 calendar days, or any order for relief is entered in any such proceeding. 
 (e) The payments and benefits to which Employee is entitled under Section 6.2(a), Section 6.2(b) and Section 6.2(c) are referred to as “Severance.” All other Company
obligations to Employee pursuant to this Agreement other than Employee’s accrued benefits under the Company’s benefit and welfare plans and [his/her] rights to indemnification and continued coverage under the Company’s D&O
Policies will automatically terminate and be completely extinguished as of the Termination Date. 
 6.3 Resignation of
Employee for Good Reason. 
 (a) Other than during the twelve (12) month period commencing on the date of a Change
of Control (such twelve (12) month period, the “Change of Control Protection Period”), Employee may resign for “Good Reason” upon notice to the Company within thirty (30) days following the
relevant event or condition if any of the following occurs without Employee’s express consent: 
 (i) The Board or Company
(A) alters Employee’s duties, responsibilities or title resulting in a significant diminution of Employee’s position, duties, responsibilities or status with the Company or, (B) requires Employee to report to anyone other than
the most senior executive of the Company if the Employee previously reported to the most senior executive of the Company or (C) reduces Employee’s Base Salary, unless the base salaries of all other employees of the Company at the Vice
President level or above are proportionately reduced and such reduction does not exceed 10% of Employee’s Base Salary; 

(ii) The Board or Company transfers or assigns Employee to any location that is more than fifty (50) miles from the location of
Employee’s principal office. Required travel on the Company’s business that is consistent with the business travel obligations of Employee’s position is excluded from this Section 6.3(a)(ii); or 

  
 - 6 -

 (iii) The Company materially breaches its obligations under this Agreement, but only after
Employee has provided written notice to the Company specifying such material breach and the Company fails to cure such breach within 20 days after its receipt of such notice. 
 (b) During the Change of Control Protection Period, Employee may resign for “Good Reason” upon the occurrence of any of the following events or conditions without Employee’s
express consent: 
 (i) A material adverse change in Employee’s duties, responsibilities or title as in effect at any time
within one year preceding the date of a Change of Control or at any time thereafter; the assignment to Employee of any duties or responsibilities which are inconsistent with [his/her] duties, responsibilities or title as in effect at any time
within one year preceding the date of a Change of Control or at any time thereafter; or any removal of Employee from or failure to reappoint or reelect him/her to any of such offices or positions, except in connection with the termination of
[his/her] employment for Disability, Cause, as a result of [his/her] death or by Employee other than for Good Reason; 
 (ii) A material reduction in Employee’s annual salary or target annual bonus opportunity as in effect at any time within one year preceding the date of a Change of Control or at any time thereafter;
provided, however, that a reduction by more than 10% in Employee’s annual salary or target annual bonus opportunity shall be considered a material reduction for purposes of this Section 6.3(b)(ii); 

(iii) The Board or Company transfers or assigns Employee to any location that is more than fifty (50) miles from the location of
Employee’s principal office prior to the Change of Control. Required travel on the Company’s business that is consistent with the business travel obligations of Employee’s position is excluded from this Section 6.3(b)(iii);

 (iv) The failure by the Company to (A) provide Employee with compensation and benefits, in the aggregate, at least
equal (in terms of benefit levels and/or reward opportunities) to those provided for under a material employee benefit plan, program and practice in which Employee was participating at any time within one year preceding the date of a Change of
Control or at any time thereafter, or (B) permit Employee to participate in any or all incentive, savings, retirement plans and benefit plans, fringe benefits, practices, policies and programs applicable generally to other similarly situated
employees of the Company and affiliated companies of the Company (including any successors to the Company and affiliated companies of the Company); 
 (v) The Company materially breaches its obligations under this Agreement; 
 (vi)
Any purported termination of Employee’s employment for Cause by the Company which does not comply with the terms of Section 6.1; or 

  
 - 7 -

 (vii) The failure of the Company to obtain an agreement, satisfactory to Employee, from any
successors and to assume and agree to perform this Agreement. 
 Notwithstanding anything to the contrary in Sections 6.3(b)(i)
through (vii) above, Employee shall provide written notice to the Company of any actual or perceived occurrence of any of the foregoing events which could give rise to a “Good Reason” termination by Employee, and the Company shall
have twenty (20) days from the date of such notice to cure any alleged deficiency to the extent curable. 
 6.4
Resignation by Employee Without Good Reason. Employee may voluntarily resign position with the Company without Good Reason at any time on thirty (30) days’ advance written notice. In the event Employee’s resignation is
without Good Reason, Employee will be entitled to receive, on Employee’s first regular payday following the Termination Date, a lump sum payment equivalent to the Accrued Benefits. All other Company obligations to Employee pursuant to this
Agreement other than Employee’s accrued benefits under the Company’s benefit and welfare plans and [his/her] rights to indemnification and continued coverage under the Company’s D&O Policies will automatically terminate and
be completely extinguished. 
 6.5 Employee’s Execution of Release and Timing of Payments. 

(a) Release. Notwithstanding the foregoing, as a condition to the payment of any severance pursuant to Sections 6.2(a) or
6.6(b)(i) and (iii), Employee will be required to execute, deliver and not revoke, within 60 days following the Termination Date, a release provided by the Company which contains a full and general release of claims in favor of the Company and its
affiliates, which release shall not include a waiver of Employee’s Accrued Benefits under the Company’s benefit and welfare plans or [his/her] rights to indemnification and continued coverage under the D&O Policies
(“Release”). If the Release has not been executed, delivered and become irrevocable by Employee within the statutory revocation period, no payments under Sections 6.2(a) or 6.6(b)(i) and (iii), will be or become payable.
Notwithstanding the foregoing, if the Company does not deliver the Release to Employee within three (3) business days following the Termination Date, then any requirement for Employee to execute, deliver and not revoke the Release as a
condition of receiving any payments under Sections 6.2(a) or 6.6(b)(i) and (iii) will have no effect, and Employee will be entitled to receive any payments to which Employee otherwise qualifies under Sections 6.2(a) or 6.6(b)(i) and (iii).

 (b) Time of Payments. Unless otherwise stated and subject to Sections 6.5(a) and 9.12
hereof, all payments and reimbursements required to be made under this Section 6 to Employee (including any payments or reimbursements to which Employee is entitled in respect of the period commencing on the Termination Date and ending on the
60th day following the Termination Date) shall be made or
shall commence on the 60th day following the Termination
Date; provided, however, all payments required to be made under Section 6.2(b) to Employee shall be made or shall commence on the 60th day following the later of: (i) the Termination Date and (ii) the date of the Change in Control.

  
 - 8 -

 6.6 Termination Upon Death or Disability. 

(a) Death. Employee’s employment will terminate automatically upon death of Employee. In the event of Employee’s
death, the Accrued Benefits shall be paid, on Employee’s first regular payday following the Termination Date, to the beneficiary designated in writing by Employee (“Beneficiary”) or, if no such Beneficiary is designated,
to Employee’s estate. In addition, (i) commencing on the Termination Date, the Company will continue Employee’s Base Salary until the earlier of six months from the Termination Date or the commencement of death benefits under any
existing Company Group Life Insurance Plan, (ii) within sixty (60) days following the Termination Date, the Company shall pay any unpaid Annual Bonus with respect to the calendar year ended prior to the termination of Employee’s
employment and a pro rata Annual Bonus (based upon [his/her] target Annual Bonus) for the year in which the termination of employment occurs; (iii) the Company shall fully accelerate vesting of any and all unvested stock options,
restricted stock units and restricted stock grants held by Employee; and (iv) the Company shall continue the Employee’s right to indemnification and coverage under the D&O Policies. 

(b) Disability. In the event that Employee becomes physically or mentally disabled such that he/she is unable to
perform [his/her] duties for a period of three (3) consecutive months as determined by a medical professional (“Disability”), the Company may terminate Employee’s employment, unless otherwise prohibited by
law. In the event of termination due to Disability, Employee shall be paid, on Employee’s first regular payday following the Termination Date, a lump sum payment equivalent to the Accrued Benefits. In addition, (i) the Company will pay
Employee a cash lump sum in an amount equal to half of Employee’s Base Salary; (ii) the Company shall pay any unpaid Annual Bonus with respect to the calendar year ended prior to the termination of Employee’s employment and a pro rata
Annual Bonus (based upon [his/her] target Annual Bonus) for the year in which the termination of employment occurs; (iii) the Company shall fully accelerate vesting of any and all unvested stock options, restricted stock units and
restricted stock grants held by Employee; and (iv) the Company shall continue the Employee’s right to indemnification and coverage under the D&O Policies. 
 6.7 Board Action. The Company agrees to take all actions required by the Board or otherwise to accelerate Employee’s unvested stock options, restricted stock units and restricted stock
grants as required by Sections 6.2 or 6.6. 
 6.8 Adjustment of Payments and Benefits. Notwithstanding any
provision of this Agreement to the contrary, if any payment or benefit to be paid or provided under this Agreement or otherwise would be an “Excess Parachute Payment,” within the meaning of Section 280G of the Code, or
any successor provision thereto, but for the application of this sentence, then the payments and benefits to be paid or provided hereunder shall be reduced to the minimum extent necessary (but in no event to less than zero) so that no portion of any
such payment or benefit, as so reduced, constitutes an Excess Parachute Payment; provided, however, that the foregoing reduction shall be made only if and to the extent that such reduction would result in an increase in the aggregate payments and
benefits to be provided, determined on an after-tax basis (taking into account the excise tax imposed pursuant to Section 4999 of the Code, or any successor provision thereto, any tax imposed by any comparable provision of state law,

  
 - 9 -

 
and any applicable federal, state and local income taxes). The determination of whether any reduction in such payments or benefits to be provided hereunder is required pursuant to the preceding
sentence shall be made at the expense of the Company, if requested by Employee or the Company, by the Company’s independent accountants. The fact that Employee’s right to payments or benefits may be reduced by reason of the limitations
contained in this Section 6.8 shall not of itself limit or otherwise affect any other rights of Employee under this Agreement. In the event that any payment or benefit intended to be provided hereunder is required to be reduced pursuant to this
Section 6.8, such payments or benefits will be reduced in the following order: (a) the lump sum severance payment described in Section 6.2(a)(i) (multiple of Base Salary); (b) the lump sum severance payment described in Section 6.2(a)(ii)
(multiple of target Annual Bonus); (c) the lump sum severance payment described in Section 6.2(b)(i) (multiple of Base Salary); (d) the lump sum severance payment described in Section 6.2(b)(ii) (multiple of target Annual Bonus);
(e) the benefits described in Section 6.2(c)(ii) (reimbursement for certain outplacement services and moving expenses); (f) the benefits described in Section 6.2(c)(iii) (reimbursement for cost of continued medical and dental benefits);
(g) the benefits described in Section 6.2(c)(iv) (unpaid Annual Bonus with respect to year prior to year of termination); and (h) the benefits described in Section 6.2(c)(v) (accelerated vesting of equity awards). 

7. Agreement Not to Compete. 
 7.1 No Employment with, or Connection to, Competitor. Employee agrees that, during the term of employment with the Company and for a period of nine (9) following the Termination Date,
Employee will not, without securing the prior written permission of the Company: 
 (a) be employed by, act as an agent for, or
consult with or otherwise perform services for, a Competitor (as defined below); or 
 (b) own any equity interest in, manage
or participate in the management (as an officer, director, partner, member or otherwise) of, or be connected in any other manner with, a Competitor, except that this section shall not restrict Employee from owning less than one percent (1%) of
the equity interests of any publicly held entity. 
 7.2 Nonsolicitation of Company Employees and Customers.
Employee agrees that for a period of one (1) year following the Termination Date, Employee will not, without securing the prior written permission of the Company, induce or attempt to induce any Employee, officer, director, agent, independent
contractor, consultant, customer, strategic partner, licensor, licensee, supplier or other service provider of the Company to terminate a relationship with, cease providing services or products to, or purchasing products or services from, the
Company. 
 7.3 Definition of Competitor. The term “Competitor” as used in this Agreement
means any individual or entity that is directly or indirectly engaged in the development and/or commercialization in the United States of one or more ex vivo cellular immunotherapies for the therapeutic treatment of cancer, which ex vivo cellular
immunotherapies generate twenty percent (20%) or more of either the annual gross revenue or worldwide operating expense of such Competitor in the United States. The term “Competitor”

  
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also includes an individual or entity that is preparing to directly or indirectly engage in the development and/or commercialization in the United States of ex vivo cellular immunotherapies, if
such ex vivo immunotherapies are anticipated to generate twenty (20%) or more of either the annual gross revenue or annual operating expense of such Competitor in the United States during the first calendar year of development and/or
commercialization. 
 7.4 Reasonableness of Restrictions. The Company and Employee agree that, in light of all of
the facts and circumstances relating to the relationship that exists and is expected to exist between the Company and Employee, these restrictions (including, but not limited to, the scope of the restricted activities, the duration of the
restrictions, and the geographic extent of the restrictions) are fair and reasonably necessary for the protection of the goodwill and other protectable interests of the Company. If a court or arbitrator of competent jurisdiction declines to enforce
any of these restrictions, the Company and Employee agree that the restrictions shall be enforceable to the maximum extent allowed by law. 
 8. Legal Fees and Expenses. Unless prohibited by law, if Employee prevails on at least one substantive issue in seeking to enforce the Company’s obligations under this Agreement, the
Company shall pay and be solely responsible for any and all costs and expenses (including attorneys’ fees) incurred by Employee in connection with Employee’s action to enforce the Company’s obligations under this Agreement. The
Company shall pay directly or reimburse Employee for any and all such costs and expenses within sixty (60) calendar days following the presentation by Employee or by counsel selected from time to time by Employee of a statement or statements
prepared by Employee or by such counsel of the amount of such costs and expenses. The Company shall also pay to Employee interest (calculated at the base rate from time to time in effect at Bank of America, compounded monthly) on any payments or
benefits that are paid or provided to Employee later than the date on which due under the terms of this Agreement. 
 In order to
comply with Section 409A of the Code, (a) in no event will the payments by the Company under Section 8 of this Agreement be made later than the end of the calendar year next following the calendar year in which such fees and expenses
were incurred; Employee shall be required to submit an invoice for such fees and expenses at least 10 days before the end of the calendar year next following the calendar year in which such fees and expenses were incurred; (b) the amount of
such legal fees and expenses that the Company is obligated to pay in any given calendar year will not affect the legal fees and expenses that the Company is obligated to pay in any other calendar year; (c) the Company’s obligation to pay
Employee’s legal fees will terminate on the fifth anniversary of the termination of this Agreement; and (d) Employee’s right to have the Company pay such legal fees and expenses may not be liquidated or exchanged for any other
benefit. 

  
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 9. General Provisions. 

9.1 Successors and Assigns. The rights and obligations of the Company under this Agreement shall inure to the benefit of
and shall be binding upon the successors and assigns of the Company. Employee shall not be entitled to assign any of Employee’s rights or obligations under this Agreement. 

9.2 Waiver. Either party’s failure to enforce any provision of this Agreement shall not in any way be construed as a
waiver of any such provision, or prevent that party thereafter from enforcing each and every other provision of this Agreement. 

9.3 Severability. In the event any provision of this Agreement is found to be unenforceable by an arbitrator or court of
competent jurisdiction, such provision shall be deemed modified to the extent necessary to allow enforceability of the provision as so limited, it being intended that the parties shall receive the benefits contemplated in this Agreement to the
fullest extent permitted by law. If a deemed modification is not satisfactory in the judgment of such arbitrator or court, the unenforceable provision shall be deemed deleted, and the validity and enforceability of the remaining provisions shall not
be affected. 
 9.4 Interpretation; Construction. The headings set forth in this Agreement are for convenience
only and shall not be used in interpreting this Agreement. Both parties have participated in the negotiation of this Agreement. Therefore, the normal rule of construction to the effect that any ambiguities are to be resolved against the drafting
party shall not be employed in the interpretation of this Agreement. 
 9.5 Notices. Any notice required or
permitted by this Agreement shall be in writing and shall be delivered as follows with notice deemed given as indicated: (a) by personal delivery when delivered personally; (b) by overnight courier upon written verification of receipt;
(c) by telecopy or facsimile transmission upon acknowledgment of receipt of electronic transmission; or (d) by certified or registered mail, return receipt requested, upon verification of receipt. Notice shall be sent to the addresses set
forth below, or such other address as either party may specify in writing. 
 9.6 Survival. Section 6
(“Separation of Employee’s Employment”), Section 7 (“Confidentiality; Agreement Not to Compete”), Section 8 (“Legal Fees and Expenses”), and Section 9 (“General Provisions”) of this
Agreement shall survive Employee’s employment by the Company. 
 9.7 Entire Agreement. This Agreement, the
Company’s stock option plan and documents reflecting options and restricted stock granted to Employee, the Proprietary Information and Inventions Agreement entered into by Employee at the commencement of employment with the Company, and the
Indemnity Agreement entered into by the Company and Employee, if any, constitute the entire agreement between the parties relating to this subject matter and supersede all prior or simultaneous representations, discussions, negotiations, and
agreements, whether written or oral. This Agreement may be amended or modified only with the written consent of Employee and a duly authorized officer of the Company. No oral waiver, amendment or modification will be effective under any
circumstances whatsoever. 

  
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 9.8 Injunctive Relief. Notwithstanding the foregoing, any action brought by
the Company under this Agreement seeking a temporary restraining order, temporary and/or permanent injunction and/or decree of specific performance of the terms of this Agreement may be brought in any court of competent jurisdiction. The Company
shall not be required to post a bond as a condition for the granting of such relief. 
 9.9 Governing Law and
Venue. This Agreement shall be governed by, and construed in accordance with, the laws of the State of Washington as though made and to be fully performed in that State. Venue for any action arising from this Agreement shall be exclusively
in King County, Washington. 
 9.10 Arbitration. 

(a) Employee and the Company agree that if a dispute arises concerning or relating to Employee’s employment with the Company, or
the termination of Employee’s employment, such dispute shall be submitted to binding arbitration under the rules of the American Arbitration Association regarding resolution of employment disputes in effect at the time such dispute arises. The
arbitration shall take place in King County, Washington, before a single experienced arbitrator licensed to practice law in Washington and selected in accordance with the American Arbitration Association rules and procedures. Except as provided
below, Employee and the Company agree that this arbitration procedure will be the exclusive means of redress for any disputes relating to or arising from Employee’s employment with the Company or [his/her] termination, including disputes
over rights provided by federal, state, or local statutes, regulations, ordinances, and common law, including all laws that prohibit discrimination based on any protected classification. The parties expressly waive the right to a jury trial, and
agree that the arbitrator’s award shall be final and binding on both parties, and shall not be appealable. The arbitrator shall have discretion to award monetary and other damages, and any other relief that the arbitrator deems appropriate and
is allowed by law taking into consideration Section 8 of this Agreement. 
 (b) The Company and Employee agree that the
sole dispute that is excepted from Section 9.10 is an action seeking injunctive relief from a court of competent jurisdiction regarding enforcement and application of Section 7 of this Agreement, which action may be brought in addition to,
or in place of, an arbitration proceeding in accordance with Section 9.10. 
 9.11 Withholding. All payments
and benefits made to Employee hereunder will be subject to any payroll and withholding deductions required by applicable law. 

9.12 Compliance with Section 409A of the Code. 

(a) To the extent applicable, it is intended that the compensation arrangements under this Agreement be in full compliance with
Section 409A of the Code (it being understood that certain compensation arrangements under this Agreement are intended not to be subject to Section 409A of the Code). The Agreement shall be construed, to the maximum extent permitted, in a
manner to give effect to such intention. Notwithstanding anything in this Agreement to the contrary, distributions upon termination of Employee’s employment may only 

  
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be made upon Employee’s “separation from service” with the Company (as determined in accordance with Section 409A of the Code). Employee acknowledges that Employee has been
advised to obtain independent legal, tax or other counsel in connection with Section 409A of the Code. 
 (b) Compliance
with Section 409A of the Code. Notwithstanding any provisions of this Agreement to the contrary, if Employee is a “specified employee” (within the meaning of Section 409A of the Code and determined pursuant to policies adopted by
the Company) at the time of Employee’s separation from service and if any portion of the payments or benefits to be received by Employee upon separation from service would be considered deferred compensation under Section 409A of the Code
(“Nonqualified Deferred Compensation”), amounts that would otherwise be payable pursuant to this Agreement during the six-month period immediately following Employee’s separation from service that constitute Nonqualified Deferred
Compensation and benefits that would otherwise be provided pursuant to this Agreement during the six-month period immediately following Employee’s separation from service that constitute Nonqualified Deferred Compensation will instead be paid
or made available on the earlier of (i) the first business day of the seventh month following the date of Employee’s separation from service and (ii) Employee’s death. 

(c) With respect to any amount of expenses eligible for reimbursement under this Agreement, such expenses will be reimbursed by the
Company within thirty (30) calendar days following the date on which the Company receives the applicable invoice from Employee in accordance with the Company’s expense reimbursement policies, but in no event later than the last day of
Employee’s taxable year following the taxable year in which Employee incurs the related expenses. In no event will the reimbursements or in-kind benefits to be provided by the Company in one taxable year affect the amount of reimbursements or
in-kind benefits to be provided in any other taxable year, nor will Employee’s right to reimbursement or in-kind benefits be subject to liquidation or exchange for another benefit. 

(d) Each payment under this Agreement shall be regarded as a “separate payment” and not of a series of payments for purposes
of Section 409A of the Code. 

  
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 THE PARTIES TO THIS AGREEMENT HAVE READ THIS AGREEMENT AND FULLY UNDERSTAND EACH AND EVERY PROVISION.

  

					
	 	 	[EMPLOYEE]
		
	Dated:                     	 	  

		
		 	Address:
		
		 	  

		 	  

		
		 	DENDREON CORPORATION
			
	Dated:                     	 	By:	 	  

			
		 	Its:	 	
			
		 	Address:	 	
		 	  

		 	  

  
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