Document:

<PAGE>   1

                                                                   EXHIBIT 10.18

                         NORTHWEST BIOTHERAPEUTICS, INC.

                 2001 NONEMPLOYEE DIRECTOR STOCK INCENTIVE PLAN

        1. PURPOSES OF THE PLAN. The purposes of this 2001 Nonemployee Director
Stock Incentive Plan (the "Plan") are to promote the long-term success of
Northwest Biotherapeutics, Inc. (the "Company") by creating a long-term
mutuality of interests between the nonemployee directors and stockholders of the
Company, to provide an additional inducement for such directors to remain with
the Company, and to provide a means through which the Company may attract able
persons to serve as directors of the Company.

        2. ADMINISTRATION.

                a. The Plan shall be administered by the Compensation Committee
(the "Committee") of the Board of Directors of the Company (the "Board").

                b. The Committee shall interpret the Plan and prescribe such
rules, regulations and procedures in connection with the operations of the Plan
as it shall deem to be necessary and advisable for the administration of the
Plan consistent with the purposes of the Plan. All questions of interpretation
and application of the Plan, or as to stock options granted under the Plan,
shall be subject to the determination of the Committee, which shall be final and
binding.

                c. Notwithstanding the above, the selection of the directors to
whom stock options are to be granted, the timing of such grants, the number of
shares subject to any stock option, the exercise price of any stock option, the
periods during which any stock option may be exercised and the term of any stock
option shall be as hereinafter provided, and the Committee shall have no
discretion as to such matters.

        3. SHARES AVAILABLE UNDER THE PLAN. The aggregate number of shares which
may be issued and as to which grants of stock options may be made under the Plan
is 200,000 shares of the common stock of the Company (without taking into effect
any split of such shares), $0.001 par value (the "Common Stock"), subject to
adjustment and substitution as set forth in Section 6. If any stock option
granted under the Plan is canceled by mutual consent or terminates or expires
for any reason without having been exercised in full, the number of shares
subject to such option shall again be available for purposes of the Plan. The
shares which may be issued under the Plan may be authorized but unissued shares,
treasury shares, or both.

        4. GRANT OF STOCK OPTIONS. On the third business day following the day
of each annual meeting of the stockholders of the Company, commencing in 2002,
each person who is then a member of the Board and who is not then an employee of
the Company or any of its subsidiaries and is not then an independent consultant
(other than in his or her capacity as a member of the Board) to the Company or
any of its subsidiaries (collectively a "Nonemployee Director") shall be
granted, automatically and without further action by the Board or the Committee,
a "nonstatutory

<PAGE>   2

stock option" (i.e., a stock option which does not qualify under Section 422 or
423 of the Internal Revenue Code of 1986 (the "Code")) to purchase five thousand
(5,000) shares of Common Stock, subject to adjustment and substitution as set
forth in Section 6. If the number of shares then remaining available for the
grant of stock options under the Plan at any time is not sufficient for each
Nonemployee Director then eligible to be granted an option for five thousand
(5,000) shares (or the number of adjusted or substituted shares pursuant to
Section 6), then each such Nonemployee Director shall be granted an option for a
number of whole shares equal to the number of shares then remaining available
divided by the number of Nonemployee Directors then eligible for grant of an
option in accordance with this Section 4, disregarding any fractions of a share.

        5. TERMS AND CONDITIONS OF STOCK OPTIONS. Stock options granted under
the Plan shall be subject to the following terms and conditions:

                a. The purchase price at which each stock option may be
exercised (the "Option Price") shall be one hundred percent (100%) of the fair
market value of the shares of Common Stock covered by the stock option on the
date of grant, determined as provided in Section 5.g.

                b. The Option Price shall be paid in full upon exercise, in cash
in United States dollars (including check, bank draft or money order); provided,
however, that in lieu of such cash the person exercising the stock option may
pay the Option Price in whole or in part by delivering to the Company shares of
the Common Stock having a fair market value on the date of exercise of the stock
option, determined as provided in Section 5.g, equal to the Option Price for the
shares being purchased; except that (i) any portion of the Option Price
representing a fraction of a share shall in any event be paid in cash, and (ii)
no shares of the Common Stock which have been held for less than six months may
be delivered in payment of the Option Price of a stock option. Delivery of
shares may also be accomplished through the effective transfer to the Company of
shares held by a broker or other agent. The Company will also cooperate with any
person exercising a stock option who participates in a cashless exercise program
of a broker or other agent under which all or part of the shares received upon
exercise of the stock option are sold through the broker or other agent or under
which the broker or other agent make a loan to such person. Notwithstanding the
foregoing, the exercise of the stock option shall not be deemed to occur and no
shares of Common Stock will be issued by the Company upon exercise of the stock
option until the Company has received payment of the Option Price in full. The
date of exercise of a stock option shall be determined under procedures
established by the Committee, and as of the date of exercise, the person
exercising the stock option shall be considered for all purposes to be the owner
of the shares of Common Stock with respect to which the stock option has been
exercised. Payment of the Option Price with shares shall not increase the number
of shares of the Common Stock which may be issued under the Plan as provided in
Section 3.

                c. No stock option shall be exercisable during the first six
months of its term except in case of death as provided in Section 5.e. Subject
to the preceding sentence and subject to Section 5.e, which provides for earlier
termination of a stock option under certain circumstances, each stock option
shall be exercisable for ten years from the date of grant and not thereafter. A
stock option to the extent exercisable at any time may be exercised in whole or
in part.

                                       2
<PAGE>   3

                d. No stock option shall be transferable by the grantee
otherwise than by will, or if the grantee dies intestate, by the laws of descent
and distribution of the state of domicile of the grantee at the time of death.

                e. If a grantee ceases to be a director of the Company for any
reason, any outstanding stock options held by the grantee shall be exercisable
according to the following provisions:

                        (i) If a grantee ceases to be a director of the Company
        for any reason other than resignation, removal for cause, or death, any
        outstanding stock option held by such grantee shall be exercisable by
        the grantee (but only if exercisable by the grantee immediately prior to
        ceasing to be director) at any time prior to the expiration date of such
        stock option or within three years after the date the grantee ceases to
        be a director, whichever is the shorter period;

                        (ii) If during his term of office as a director a
        grantee resigns from the Board or is removed from office for cause, any
        outstanding stock option held by the grantee which is not exercisable by
        the grantee immediately prior to resignation or removal shall terminate
        as of the date of resignation or removal, and any outstanding stock
        option held by the grantee which is exercisable by the grantee
        immediately prior to resignation or removal shall be exercisable by the
        grantee at any time prior to the expiration date of such stock option or
        within three months after the date of resignation or removal of the
        grantee, whichever is the shorter period;

                        (iii) Following the death of a grantee during service as
        a director of the Company, any outstanding stock option held by the
        grantee at the time of death (whether or not exercisable by the grantee
        immediately prior to death) shall be exercisable by the person entitled
        to do so under the will of the grantee, or, if the grantee shall fail to
        make testamentary disposition of the stock option or shall die
        intestate, by the legal representative of the grantee at any time prior
        to the expiration date of such stock option or within three years after
        the date of death of the grantee, whichever is the shorter period; and

                        (iv) Following the death of a grantee after ceasing to
        be a director and during a period when a stock option is exercisable
        under clause (ii) above, the stock option shall be exercisable by such
        person entitled to do so under the will of the grantee or by such legal
        representative at any time prior to the expiration date of the stock
        option or within one year after the date of death, whichever is the
        shorter period.

        A stock option held by a grantee who has ceased to be a director of the
Company shall terminate upon the expiration of the applicable exercise period,
if any, specified in this Section 5.e.

                f. All stock options shall be confirmed by an agreement, or an
amendment thereto, which shall be executed on behalf of the Company by the Chief
Executive Officer (if other than the President), the President or any Vice
President and by the grantee.

                                       3
<PAGE>   4

                g. Fair market value of the Common Stock shall be the mean
between the following prices, as applicable, for the date as of which fair
market value is to be determined, as quoted in The Wall Street Journal (or in
such other reliable publication as the Committee, in its discretion, may
determine to rely upon): (i) if the Common Stock is listed on the New York Stock
Exchange, the highest and lowest sales prices per share of the Common Stock as
quoted in the NYSE-Composite Transactions listing for such date, (ii) if the
Common Stock is not listed on such exchange, the highest and lowest sales prices
per share of the Common Stock for such date on (or on any composite index
including) the principal United States securities exchange registered under the
1934 Act on which the Common Stock is listed, or (iii) if the Common Stock is
not listed on any such exchange, the highest and lowest sales prices per share
of the Common Stock for such date on the National Association of Securities
Dealers Automated Quotations System or any successor system then in use
("NASDAQ"). If there are no such sale price quotations for the date as of which
fair market value is to be determined but there are such sale price quotations
within a reasonable period both before and after such date, then fair market
value shall be determined by taking a weighted average of the means between the
highest and lowest sales prices per share of the Common Stock as so quoted on
the nearest date before and the nearest date after the date as of which fair
market value is to be determined. The average should be weighted inversely by
the respective numbers of trading days between the selling dates and the date as
of which fair market value is to be determined. If there are no such sale price
quotations on or within a reasonable period both before and after the date as of
which fair market value is to be determined, then fair market value of the
Common Stock shall be the mean between the bona fide bid and asked prices per
share of Common Stock as so quoted for such date on NASDAQ, or if none, the
weighted average of the means between such bona fide bid and asked prices on the
nearest trading date before and the nearest trading date after the date as of
which fair market value is to be determined, if both such dates are within a
reasonable period. The average is to be determined in the manner described above
in this Section 5.g. If the fair market value of the Common Stock cannot be
determined on the basis previously set forth in this Section 5.g for the date as
of which fair market value is to be determined, the Committee shall in good
faith determine the fair market value of the Common Stock on such date. Fair
market value shall be determined without regard to any restriction other than a
restriction which, by its terms, will never lapse.

                h. The obligation of the Company to issue shares of the Common
Stock under the Plan shall be subject to (i) the effectiveness of a registration
statement under the Securities Act of 1933, as amended, with respect to such
shares, if deemed necessary or appropriate by counsel for the Company, (ii) the
condition that the shares shall have been listed (or authorized for listing upon
official notice of issuance) upon each stock exchange, if any, on which the
Common Stock may then be listed and (iii) all other applicable laws,
regulations, rules and orders which may then be in effect.

        Subject to the foregoing provision of this Section 5 and the other
provisions of the Plan, any stock option granted under the Plan shall be subject
to such restrictions and other terms and conditions, if any, as shall be
determined, in its discretion, by the Committee and set forth in the agreement
referred to in Section 5.f, or an amendment thereto.

        6. ADJUSTMENT AND SUBSTITUTION OF SHARES. If a dividend or other
distribution shall be declared upon the Common Stock payable in shares of the
Common Stock, then (i) the number of shares of the Common Stock set forth in
Section 4, (ii) the number of shares of the Common Stock

                                       4
<PAGE>   5

then subject to any outstanding stock options, and (iii) the number of shares of
the Common Stock which may be issued under the Plan but are not then subject to
outstanding stock options on the date fixed for determining the stockholders
entitled to receive such stock dividend or distribution, shall be adjusted by
adding thereto the number of shares of the Common Stock which would have been
distributable thereon if such shares had been outstanding on such date.

        If the outstanding shares of the Common Stock shall be changed into or
exchangeable for a different number or kind of shares of stock or other
securities of the Company or another Company, whether through reorganization,
reclassification, recapitalization, stock split up, combination of shares,
merger or consolidation, then there shall be substituted for each share of the
Common Stock set forth in Section 4, for each share of the Common Stock subject
to any then outstanding stock option and for each share of the Common Stock
which may be issued under the Plan but which is not then subject to any
outstanding stock option, the number and kind of shares of stock or other
securities into which each outstanding share of the Common Stock shall be so
changed or for which each such share shall be exchangeable.

        In case of any adjustment or substitution as provided for in the first
two paragraphs of this Section 6, the aggregate Option Price for all shares
subject to each then outstanding stock option prior to such adjustment or
substitution shall be the aggregate Option Price for all shares of stock or
other securities (including any fraction) to which such shares shall have been
adjusted or which shall have been substituted for such shares. Any new Option
Price per share shall be carried to at least three decimal places with the last
decimal place rounded upwards to the nearest whole number.

        If the outstanding Common Stock shall be changed in value by reason of
any spin-off, split off or split up, or dividend in partial liquidation,
dividend in property other than cash or extraordinary distribution to holders of
the Common Stock, the Committee shall make any adjustments to any then
outstanding stock option which it determines are equitably required to prevent
dilution or enlargement of the rights of grantees which would otherwise result
from any such transaction.

        No adjustment or substitution provided for in this Section 6 shall
require the Company to issue or sell a fraction of a share or other security.
Accordingly, all fractional shares or other securities which result from any
such adjustment or substitution shall be eliminated and not carried forward to
any subsequent adjustment or substitution.

        Except as provided in this Section 6, a grantee shall have no rights by
reason of any issue by the Company of stock of any class or securities
convertible into stock of any class, any subdivision or consolidation of shares
of stock of any class, the payment of any stock dividend or any other increase
or decrease in the number of shares of stock of any class.

        7. EFFECT OF THE PLAN ON THE RIGHTS OF COMPANY AND SHAREHOLDERS. Nothing
in the Plan, in any stock option granted under the Plan, or in any stock option
agreement shall confer any right to any person to continue as a director of the
Company or interfere in any way with the rights of the stockholders of the
Company or the Board to elect and remove directors.

                                       5
<PAGE>   6

        8. AMENDMENT AND TERMINATION. The right to amend or to terminate the
Plan at any time are hereby specifically reserved to the Board; provided that no
such termination shall terminate any outstanding stock options granted under the
Plan; and provided further that no amendment of the Plan shall be made without
shareholder approval if shareholder approval of the amendment is at the time
required for stock options under the Plan to qualify for any exemption from
Section 16(b) of the 1934 Act provided by Rule 16b-3, or any successor rule, or
by the rules of any stock exchange on which the Common Stock may then be listed.
No amendment or termination of the Plan shall, without the written consent of
the holder of a stock option theretofore awarded under the Plan, adversely
affect the rights of such holder with respect thereto.

                                       6<PAGE>   1
                                                                   EXHIBIT 10.19

                         NORTHWEST BIOTHERAPEUTICS, INC.

                          EMPLOYEE STOCK PURCHASE PLAN

SECTION 1.  PURPOSE OF THE PLAN

        The purpose of the Plan is to provide Eligible Employees with an
opportunity to increase their proprietary interest in the success of the Company
by purchasing Stock from the Company on favorable terms and to pay for such
purchases through payroll deductions. The Plan is intended to qualify under
Section 423 of the Code.

SECTION 2.  ADMINISTRATION OF THE PLAN

        (a) COMMITTEE COMPOSITION. The Plan shall be administered by the
Committee.

        (b) COMMITTEE RESPONSIBILITIES. The Committee shall interpret the Plan
and make all other policy decisions relating to the operation of the Plan. The
Committee may adopt such rules, guidelines and forms as it deems appropriate to
implement the Plan. The Committee's determinations under the Plan shall be final
and binding on all persons.

SECTION 3.  ENROLLMENT AND PARTICIPATION

        (a) OFFERING PERIODS. While the Plan is in effect, two Offering Periods
shall commence in each calendar year. The Offering Periods shall consist of the
six-month periods commencing on each April 1 and October 1. The Plan shall
become effective upon the consummation of a firm underwritten public offering of
the Company's common stock.

        (b) ENROLLMENT. Any individual who, on the day preceding the first day
of an Offering Period, qualifies as an Eligible Employee may elect to become a
Participant in the Plan for such Offering Period by executing the enrollment
form prescribed for this purpose by the Committee. The enrollment form shall be
filed with the Company at the prescribed location not later than three (3) days
prior to the commencement of such Offering Period.

(c) DURATION OF PARTICIPATION. Once enrolled in the Plan, a Participant shall
continue to participate in the Plan until he or she ceases to be an Eligible
Employee, withdraws from the Plan under Section 5(a) or reaches the end of the
Offering Period in which his or her employee contributions were discontinued
under Section 4(d) or 8(b). A Participant who discontinued employee
contributions under Section 4(d) or withdrew from the Plan under Section 5(a)
may again become a Participant, if he or she then is an Eligible Employee, by
following the procedure described in Subsection (b) above. A Participant whose
employee contributions were discontinued automatically under Section 8(b) shall
automatically resume

<PAGE>   2

participation at the beginning of the earliest Offering Period ending in the
next calendar year, if he or she then is an Eligible Employee.

SECTION 4.  EMPLOYEE CONTRIBUTIONS

        (a) FREQUENCY OF PAYROLL DEDUCTIONS. A Participant may purchase shares
of Stock under the Plan solely by means of payroll deductions. Payroll
deductions, as designated by the Participant pursuant to Subsection (b) below,
shall occur on each payday during participation in the Plan.

        (b) AMOUNT OF PAYROLL DEDUCTIONS. An Eligible Employee shall designate
on the enrollment form the portion of his or her Compensation that he or she
elects to have withheld for the purchase of Stock. Such portion shall be a whole
percentage of the Eligible Employee's Compensation, but not less than one
percent (1%) nor more than ten percent (10%).

        (c) CHANGING WITHHOLDING RATE. If a Participant wishes to change the
rate of payroll withholding, he or she may do so by filing a new enrollment form
with the Company at the prescribed location at any time. The new withholding
rate shall be effective as soon as reasonably practicable after such form has
been received by the Company.

        (d) DISCONTINUING PAYROLL DEDUCTIONS. If a Participant wishes to
discontinue employee contributions entirely, he or she may do so by filing a new
enrollment form with the Company at the prescribed location at any time. Payroll
withholding shall cease as soon as reasonably practicable after such form has
been received by the Company. (In addition, employee contributions may be
discontinued automatically pursuant to Section 8(b).) A Participant who has
discontinued employee contributions may resume such contributions by filing a
new enrollment form with the Company at the prescribed location. Payroll
withholding shall resume as soon as reasonably practicable after such form has
been received by the Company.

        (e) LIMIT ON NUMBER OF ELECTIONS. No Participant shall make more than
four (4) elections under Subsection (c) or (d) above during any Offering Period.

SECTION 5.  WITHDRAWAL FROM THE PLAN

        (a) WITHDRAWAL. A Participant may elect to withdraw from the Plan by
filing the prescribed form with the Company at the prescribed location at any
time before the last day of an Offering Period. As soon as reasonably
practicable thereafter, payroll deductions shall cease and the entire amount
credited to the Participant's Plan Account shall be refunded to him or her in
cash, without interest. No partial withdrawals shall be permitted.

        (b) RE-ENROLLMENT AFTER WITHDRAWAL. A former Participant who has
withdrawn from the Plan shall not be a Participant until he or she re-enrolls in
the Plan under Section 3(c). Re-enrollment may be effective only at the
commencement of an Offering Period.

                                       2
<PAGE>   3

SECTION 6.  CHANGE IN EMPLOYMENT STATUS

        (a) TERMINATION OF EMPLOYMENT. Termination of employment as an Eligible
Employee for any reason, including death, shall be treated as an automatic
withdrawal from the Plan under Section 5(a). (A transfer from one Participating
Company to another shall not be treated as a termination of employment.)

        (b) LEAVE OF ABSENCE. For purposes of the Plan, employment shall not be
deemed to terminate when the Participant goes on a military leave, a sick leave
or another bona fide leave of absence, if the leave was approved by the Company
in writing. Employment, however, shall be deemed to terminate 90 days after the
Participant goes on a leave, unless a contract or statute guarantees his or her
right to return to work. Employment shall be deemed to terminate in any event
when the approved leave ends, unless the Participant immediately returns to
work.

        (c) DEATH. In the event of the Participant's death, the amount credited
to his or her Plan Account shall be paid to a beneficiary designated by him or
her for this purpose on the prescribed form or, if none, to the Participant's
estate. Such form shall be valid only if it was filed with the Company at the
prescribed location before the Participant's death.

SECTION 7.  PLAN ACCOUNTS AND PURCHASE OF SHARES

        (a) PLAN ACCOUNTS. The Company shall maintain a Plan Account on its
books in the name of each Participant. Whenever an amount is deducted from the
Participant's Compensation under the Plan, such amount shall be credited to the
Participant's Plan Account. Amounts credited to Plan Accounts shall not be trust
funds and may be commingled with the Company's general assets and applied to
general corporate purposes. No interest shall be credited to Plan Accounts.

        (b) PURCHASE PRICE. The Purchase Price for each share of Stock purchased
at the close of an Offering Period shall be the lower of:

                (i) 85% of the Fair Market Value of such share on the last
        trading day in such Offering Period; or

                (ii) 85% of the Fair Market Value of such share on the last
        trading day before the commencement of such Offering Period.

        (c) NUMBER OF SHARES PURCHASED. As of the last day of each Offering
Period, each Participant shall be deemed to have elected to purchase the number
of shares of Stock calculated in accordance with this Subsection (c), unless the
Participant has previously elected to withdraw from the Plan in accordance with
Section 5(a). The amount then in the Participant's Plan Account shall be divided
by the Purchase Price, and the number of shares that results shall be purchased
from the Company with the funds in the Participant's Plan Account. The foregoing
notwithstanding, no Participant shall purchase more than one thousand (1,000)
shares of Stock with respect to any Offering Period nor more than the amounts of
Stock set forth in Sections 8(b)

                                       3
<PAGE>   4

and 13(a). Any fractional share, as calculated under this Subsection (c), shall
be rounded down to the next lower whole share.

        (d) AVAILABLE SHARES INSUFFICIENT. In the event that the aggregate
number of shares that all Participants elect to purchase during an Offering
Period exceeds the maximum number of shares remaining available for issuance
under Section 13(a), then the number of shares to which each Participant is
entitled shall be determined by multiplying the number of shares available for
issuance by a fraction, the numerator of which is the number of shares that such
Participant has elected to purchase and the denominator of which is the number
of shares that all Participants have elected to purchase.

        (e) ISSUANCE OF STOCK. Certificates representing the shares of Stock
purchased by a Participant under the Plan shall be issued to him or her as soon
as reasonably practicable after the close of the applicable Offering Period,
except that the Committee may determine that such shares shall be held for each
Participant's benefit by a broker designated by the Committee (unless the
Participant has elected that certificates be issued to him or her). Shares may
be registered in the name of the Participant or jointly in the name of the
Participant and his or her spouse as joint tenants with right of survivorship or
as community property.

        (f) UNUSED CASH BALANCES. Any amount remaining in the Participant's Plan
Account that represents the Purchase Price for a fractional share shall be
carried over in the Participant's Plan Account to the next Offering Period. Any
amount remaining in the Participant's Plan Account that represents the Purchase
Price for whole shares that could not be purchased by reason of Subsection (c)
above, Section 8(b) or Section 13(a) shall be refunded to the Participant in
cash, without interest.

        (g) STOCKHOLDER APPROVAL. Any other provision of the Plan
notwithstanding, no shares of Stock shall be purchased under the Plan unless and
until the Company's stockholders have approved the adoption of the Plan.

SECTION 8.  LIMITATIONS ON STOCK OWNERSHIP.

        (a) FIVE PERCENT LIMIT. Any other provision of the Plan notwithstanding,
no Participant shall be granted a right to purchase Stock under the Plan if such
Participant, immediately after his or her election to purchase such Stock, would
own stock possessing more than 5% of the total combined voting power or value of
all classes of stock of the Company or any parent or Subsidiary of the Company.
For purposes of this Subsection (a), the following rules shall apply:

                (i) Ownership of stock shall be determined after applying the
        attribution rules of Section 424(d) of the Code;

                (ii) Each Participant shall be deemed to own any stock that he
        or she has a right or option to purchase under this or any other plan;
        and

                                       4
<PAGE>   5

                (iii) Each Participant shall be deemed to have the right to
        purchase one thousand (1,000) shares of Stock under this Plan with
        respect to each Offering Period.

        (b) DOLLAR LIMIT. Any other provision of the Plan notwithstanding, no
Participant shall purchase Stock with a Fair Market Value in excess of the
following limit:

                (i) In the case of Stock purchased during an Offering Period
        that commenced in the current calendar year, the limit shall be equal to
        (A) $25,000 minus (B) the Fair Market Value of the Stock that the
        Participant previously purchased in the current calendar year under this
        Plan.

                (ii) In the case of Stock purchased during an Offering Period
        that commenced in the immediately preceding calendar year, the limit
        shall be equal to (A) $50,000 minus (B) the Fair Market Value of the
        Stock that the Participant previously purchased under this Plan in the
        current calendar year and in the immediately preceding calendar year.

        For purposes of this Subsection (b), the Fair Market Value of Stock
shall be determined in each case as of the beginning of the Offering Period in
which such Stock is purchased. If a Participant is precluded by this Subsection
(b) from purchasing additional Stock under the Plan, then his or her employee
contributions shall automatically be discontinued and shall resume at the
beginning of the earliest Offering Period ending in the next calendar year (if
he or she then is an Eligible Employee).

SECTION 9.  RIGHTS NOT TRANSFERABLE

        The rights of any Participant under the Plan, or any Participant's
interest in any Stock or moneys to which he or she may be entitled under the
Plan, shall not be transferable by voluntary or involuntary assignment or by
operation of law, or in any other manner other than by beneficiary designation
or the laws of descent and distribution. If a Participant in any manner attempts
to transfer, assign or otherwise encumber his or her rights or interest under
the Plan, other than by beneficiary designation or the laws of descent and
distribution, then such act shall be treated as an election by the Participant
to withdraw from the Plan under Section 5(a).

SECTION 10.  NO RIGHTS AS AN EMPLOYEE

        Nothing in the Plan or in any right granted under the Plan shall confer
upon the Participant any right to continue in the employ of a Participating
Company for any period of specific duration or interfere with or otherwise
restrict in any way the rights of the Participating Companies or of the
Participant, which rights are hereby expressly reserved by each, to terminate
his or her employment at any time and for any reason, with or without cause.

SECTION 11.  NO RIGHTS AS A STOCKHOLDER

        A Participant shall have no rights as a stockholder with respect to any
shares of Stock that he or she may have a right to purchase under the Plan until
such shares have been purchased on the last day of the applicable Offering
Period.

                                       5
<PAGE>   6

SECTION 12.  SECURITIES LAW REQUIREMENTS

        Shares of Stock shall not be issued under the Plan unless the issuance
and delivery of such shares comply with (or are exempt from) all applicable
requirements of law, including (without limitation) the Securities Act of 1933,
as amended, the rules and regulations promulgated thereunder, state securities
laws and regulations, and the regulations of any stock exchange or other
securities market on which the Company's securities may then be traded.

SECTION 13.  STOCK OFFERED UNDER THE PLAN

        (a) AUTHORIZED SHARES. The aggregate number of shares of Stock available
for purchase under the Plan shall be Five Hundred Thousand (500,000) subject to
adjustment pursuant to this Section 13.

        (b) ANTIDILUTION ADJUSTMENTS. The aggregate number of shares of Stock
offered under the Plan, the one thousand (1,000) share limitation described in
Section 7(c) and the price of shares that any Participant has elected to
purchase shall be adjusted proportionately by the Committee for any increase or
decrease in the number of outstanding shares of Stock resulting from a
subdivision or consolidation of shares or the payment of a stock dividend, any
other increase or decrease in such shares effected without receipt or payment of
consideration by the Company, the distribution of the shares of a Subsidiary to
the Company's stockholders or a similar event.

        (c) REORGANIZATIONS. Any other provision of the Plan notwithstanding,
immediately prior to the effective time of a Corporate Reorganization, the
Offering Period then in progress shall terminate and shares shall be purchased
pursuant to Section 7, unless the Plan is assumed by the surviving corporation
or its parent corporation pursuant to the plan of merger or consolidation. The
Plan shall in no event be construed to restrict in any way the Company's right
to undertake a dissolution, liquidation, merger, consolidation or other
reorganization.

SECTION 14.  AMENDMENT OR DISCONTINUANCE

        The Board shall have the right to amend, suspend or terminate the Plan
at any time and without notice. Except as provided in Section 13, any increase
in the aggregate number of shares of Stock to be issued under the Plan shall be
subject to approval by a vote of the stockholders of the Company. In addition,
any other amendment of the Plan shall be subject to approval by a vote of the
stockholders of the Company to the extent required by an applicable law or
regulation.

SECTION 15.  DEFINITIONS

        (a) "BOARD" means the Board of Directors of the Company, as constituted
from time to time.

        (b) "CODE" means the Internal Revenue Code of 1986, as amended.

                                       6
<PAGE>   7

        (c)    "COMMITTEE" means the Compensation Committee of the Board.

        (d) "COMPANY" means Northwest Biotherapeutics, Inc., a Delaware
corporation.

        (e) "COMPENSATION" means (i) the total compensation paid in cash to a
Participant by a Participating Company, including salaries, wages, bonuses,
incentive compensation, commissions, overtime pay and shift premiums, plus (ii)
any pre-tax contributions made by the Participant under Section 401(k) or 125 of
the Code. "Compensation" shall exclude all non-cash items, moving or relocation
allowances, cost-of-living equalization payments, car allowances, tuition
reimbursements, imputed income attributable to cars or life insurance, severance
pay, fringe benefits, contributions or benefits received under employee benefit
plans, income attributable to the exercise of stock options, and similar items.
The Committee shall determine whether a particular item is included in
Compensation.

        (f)    "CORPORATE REORGANIZATION" means:

                (i) The consummation of a merger or consolidation of the Company
        with or into another entity, or any other corporate reorganization; or

                (ii) The sale, transfer or other disposition of all or
        substantially all of the Company's assets or the complete liquidation or
        dissolution of the Company.

        (g) "ELIGIBLE EMPLOYEE" means any employee of a Participating Company
whose customary employment is for more than five months per calendar year and
for more than 20 hours per week.

        The foregoing notwithstanding, an individual shall not be considered an
Eligible Employee if his or her participation in the Plan is prohibited by the
law of any country which has jurisdiction over him or her or if he or she is
subject to a collective bargaining agreement that does not provide for
participation in the Plan.

        (h) "EXCHANGE ACT" means the Securities Exchange Act of 1934, as
amended.

        (i) "FAIR MARKET VALUE" means the market price of Stock, determined by
the Committee as follows:

               (i) If Stock was traded on The Nasdaq National Market on the date
        in question, then the Fair Market Value shall be equal to the last sale
        price quoted for such date by The Nasdaq National Market;

               (ii) If Stock was traded on a stock exchange on the date in
        question, then the Fair Market Value shall be equal to the closing price
        reported by the applicable composite transactions report for such date;
        or

                                       7
<PAGE>   8

               (iii) If none of the foregoing provisions is applicable, then the
        Fair Market Value shall be determined by the Committee in good faith on
        such basis as it deems appropriate.

        Whenever possible, the determination of Fair Market Value by the
Committee shall be based on the prices reported in the Wall Street Journal or as
reported directly to the Company by Nasdaq or a stock exchange. Such
determination shall be conclusive and binding on all persons.

        (j) "OFFERING PERIOD" means a six-month period with respect to which the
right to purchase Stock may be granted under the Plan, as determined pursuant to
Section 3(a).

        (k) "PARTICIPANT" means an Eligible Employee who elects to participate
in the Plan, as provided in Section 3(b).

        (l) "PARTICIPATING COMPANY" means (i) the Company and (ii) each present
or future Subsidiary designated by the Committee as a Participating Company.

        (m) "PLAN" means this Northwest Biotherapeutics, Inc. Employee Stock
Purchase Plan, as it may be amended from time to time.

        (n) "PLAN ACCOUNT" means the account established for each Participant
pursuant to Section 7(a).

        (o) "PURCHASE PRICE" means the price at which Participants may purchase
Stock under the Plan, as determined pursuant to Section 7(b).

        (p) "STOCK" means the Common Stock of the Company, no par value per
share.

        (q) "SUBSIDIARY" means any corporation (other than the Company) in an
unbroken chain of corporations beginning with the Company, if each of the
corporations other than the last corporation in the unbroken chain owns stock
possessing 50% or more of the total combined voting power of all classes of
stock in one of the other corporations in such chain.

                                       8

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00028-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00028-of-00352.parquet"}]]