Document:

QuickLinks
 -- Click here to rapidly navigate through this document

 
 

Exhibit 4.11    
    

        "CONFIDENTIAL TREATMENT REQUESTED. CONFIDENTIAL PORTIONS OF THIS DOCUMENT HAVE BEEN OMITTED AND HAVE BEEN SEPARATELY FILED WITH THE COMMISSION. CONFIDENTIAL
TREATMENT HAS BEEN REQUESTED WITH RESPECT TO THE OMITTED PORTIONS, WHICH ARE IDENTIFIED BY ***."

 
 

LICENSE AGREEMENT  
    

        Effective as of February 5, 2004 ("EFFECTIVE DATE"), GENETIC TECHNOLOGIES LIMITED, having an office at 60
Hanover Street, Fitzroy, Victoria 3065, Australia ("GTG") and LABORATORY CORPORATION OF AMERICA HOLDINGS, a Delaware corporation having an office at 430
South Spring Street, Burlington, NC 27215, USA ("LICENSEE"), agree as follows: 

ARTICLE I  

 BACKGROUND  

	1.1
	As
a result of privately funded research over the course of many years, GTG now holds certain intellectual property rights in a variety of countries throughout the world relating to
methods and processes used to extract gene discovery and diagnostic utility from the non-coding region of genomes.

	1.2
	LICENSEE
wishes to acquire licenses under and to obtain access to GTG's non-coding patents to the extent that they are required in accordance with applicable law in order
to: 1) provide clinical laboratory diagnostic testing services and other testing services offered by LICENSEE and/or SUBSIDIARIES of LICENSEE on humans in the United States, it territories, and
Canada ("DIAGNOSTIC TESTING PURPOSE"); and 2) provide and conduct contract clinical trials and research protocols and services in the United States, its territories, and Europe solely for
(i) assisting third parties, including, but not limited to pharmaceutical companies; and (ii) internal purposes of LICENSEE and/or SUBSIDIARIES of LICENSEE in connection with regulatory
compliance ("CLINICAL TRIALS PURPOSE").

	1.3
	GTG
is prepared to grant a non-exclusive license to LICENSEE under its non-coding patents, subject to the terms and conditions of this AGREEMENT. 

ARTICLE II  

 GENERAL DEFINITIONS AND RELATIONSHIPS AMONG DEFINITIONS  

	2.1
	"AGREEMENT"
means this document, its attachments, all addenda, schedules, exhibits, appendices, and any amendments to the foregoing.

	2.2
	"CLINICAL
TRIALS LICENSED SERVICES" means research services and clinical trials performed by LICENSEE or a SUBSIDIARY of LICENSEE and that but for the license granted herein would
infringe or contribute to the infringement of one or more claims of a LICENSED PATENT.

	2.3
	"CONFIDENTIAL
INFORMATION" means any and all information which is disclosed by either party to the other verbally, electronically, visually, or in a written or other tangible form
which is either identified at the time of disclosure as confidential or should be reasonably understood to be confidential or proprietary. CONFIDENTIAL INFORMATION includes, but is not limited to, the
specific terms and/or conditions of this AGREEMENT, trade secrets, ideas, processes, formulas, programs, software, source of supply, technology, discoveries, developments, inventions, techniques,
marketing plans, strategies, forecasts, unpublished financial statements, prices, costs, and customer lists.

	2.4
	"DIAGNOSTIC
TESTING LICENSED SERVICES" means diagnostic service testing, or other testing service offered by LICENSEE and/or SUBSIDIARIES of LICENSEE (i) performed by 

 

LICENSEE
or a SUBSIDIARY of LICENSEE; and (ii) that but for the license granted herein would infringe or contribute to the infringement of one or more claims of a LICENSED PATENT. 

	2.5
	"EXCLUDED
FIELD" means ***

	2.6
	"EXCLUSION
TIME PERIOD" means the period from the EFFECTIVE DATE until August 31, 2006.

	2.7
	"FIELD
OF USE" means, during the EXCLUSION TIME PERIOD, diagnostic service testing and other testing services offered by LICENSEE and/or SUBSIDIARIES of LICENSEE for humans and
clinical trials and research, other than the EXCLUDED FIELD, and upon expiration of the EXCLUSION TIME PERIOD means diagnostic service testing and other testing services offered by LICENSEE and/or
SUBSIDIARIES of LICENSEE for humans and clinical trials and research without limitation.

	2.8
	GTG
and LICENSEE may be commonly referred to as "parties" (in singular and plural usage, as required by the context).

	2.9
	"LICENSED
PATENT(S)" means individually or collectively (i) the United States patents of GTG listed in the attached Exhibit A; (ii) all reissues, reexaminations,
divisionals, continuations, continuations-in-part, substitutions, or other applications claiming priority from such patents and any patents which may issue on such other
applications, or extensions of such patents; and (iii) foreign counterparts of any of the foregoing.

	2.10
	"LICENSED
SERVICES" means CLINICAL TRIALS LICENSED SERVICES and DIAGNOSTIC TESTING LICENSED SERVICES.

	2.11
	***

	2.12
	"SUBSIDIARY"
means any corporation, company or other legal entity, in which more than fifty percent (50%) of the shares entitled to vote for the election of directors or persons
performing similar functions are, now or hereafter, owned or controlled, directly or indirectly by a party hereto, or jointly by the parties hereto; provided, however, that any corporation, company or
other legal entity shall be a SUBSIDIARY only for as long as such ownership or control exists.

	2.13
	"TERRITORY"
means Canada and the United States of America (including its territories).

	2.14
	"TERM"
means from the EFFECTIVE DATE until there is no longer a VALID PATENT CLAIM (due to expiration or otherwise), except as otherwise provided in Article VII.

	2.15
	"VALID
PATENT CLAIM" shall mean any claim in a filed and unabandoned patent application or unexpired patent with the LICENSED PATENTS, which claim has not been held unpatentable,
unenforceable, or invalid by a decision of a court or other governmental agency of competent jurisdiction, unappealable or unappealed within the time allowed for appeal, and which has not been finally
abandoned or admitted to be invalid or unenforceable through reissue, disclaimer or otherwise. 

ARTICLE III  

 RELEASE  

	3.1
	Upon
execution of this AGREEMENT by both parties and payment in full by LICENSEE of the *** to GTG, GTG, and any person or entity claiming through GTG (including without limitation
any affiliates, predecessors, successors or assigns of GTG), hereby waive, release and forever discharge LICENSEE, all SUBSIDIARIES of LICENSEE,  and their
respective successors, assigns, directors, officers, employees and agents, both current and former (collectively, the "RELEASED PARTIES") from
any and all claims, suits, demands, actions, losses, costs, damages, expenses, liabilities and obligations whatsoever, whether known or unknown, arising from or relating to 

2

 

(a) any
acts or omissions of the RELEASED PARTIES on or before the *** or ***, whichever is later (the "RELEASE DATE"), (b) any events, occurrences, conditions or circumstances occurring
on or before the RELEASE DATE, or (c) any transactions, relationships, arrangements or other matters of any kind or nature existing at any time on or before the RELEASE DATE (collectively, the
"RELEASED MATTERS"). This waiver and release includes, but is not limited to, any claims arising from or related to the infringement or misappropriation, or alleged infringement or misappropriation,
of any intellectual property or other proprietary rights of GTG (including without limitation the LICENSED PATENTS) by the RELEASED PARTIES. 

	3.2
	GTG
further agrees that it will not institute or participate in any legal action or administrative complaint against the RELEASED PARTIES arising out of or related to the RELEASED
MATTERS. In the event of a breach of this Article 3 of this AGREEMENT, the RELEASED PARTIES shall be entitled to recover from GTG attorneys' fees and expenses incurred by the RELEASED PARTIES
defending such lawsuit filed by, on behalf of or otherwise involving GTG. 

ARTICLE IV  

 GRANT TO LICENSEE  

	4.1
	Subject
to the terms and conditions of this AGREEMENT, GTG hereby grants to LICENSEE, during the TERM of this AGREEMENT:

	(i)
	A
non-exclusive, non-assignable, annual fee-bearing license under the LICENSED PATENTS (without the right to sublicense except to
LICENSEE's SUBSIDIARIES) to perform, use, sell, and offer to sell DIAGNOSTIC TESTING LICENSED SERVICES in the FIELD OF USE solely within the TERRITORY for the DIAGNOSTIC TESTING PURPOSE; and

	(ii)
	A
non-exclusive, non-assignable, annual fee-bearing license under the LICENSED PATENTS (without right to sublicense except to
LICENSEE's SUBSIDIARIES) to perform, use, sell, and offer to sell CLINICAL TRIALS LICENSED SERVICES in the FIELD OF USE in the United States, its territories, and Europe (regardless of where the
samples originate or where the sponsor may be located) for the CLINICAL TRIALS PURPOSE.

	4.2
	All
rights not explicitly granted to LICENSEE are reserved by GTG. Not limiting the foregoing, LICENSEE acknowledges that it is not granted any rights to any other patents or other
intellectual property rights of GTG or any third party.

	4.3
	The
rights and licenses granted by GTG in this AGREEMENT are personal to LICENSEE. Except as set forth in Section 4.4 and Section 11.6, LICENSEE shall not assign or
otherwise transfer (by operation of law or otherwise) any license or right granted hereunder or any interest therein, without the prior written consent of GTG (which may be withheld in GTG's sole and
absolute discretion). Any attempted assignment or transfer without such prior written consent shall be void and shall upon written notice by GTG terminate all rights of LICENSEE under this AGREEMENT.

	4.4
	LICENSEE
may extend the license granted under this AGREEMENT to SUBSIDIARIES of LICENSEE provided that LICENSEE ensures that such SUBSIDIARIES are bound to the same terms and
conditions of this AGREEMENT as is LICENSEE (except that such SUBSIDIARIES shall not be obligated ***, it being understood that payments by LICENSEE of the amounts under *** constitutes *** for
LICENSEE and all SUBSIDIARIES of LICENSEE).

	4.5
	***

3

 
ARTICLE V  

 CONSIDERATION  

	5.1
	Subject
to Section 5.2, LICENSEE agrees to pay to GTG the QUARTERLY LICENSE ANNUITY commencing on *** (such first payment constituting payment for the period from *** until
***. Such QUARTERLY LICENSE ANNUNITY payments are due and payable to GTG on January 1, April 1, July 1, and October 1 of each year of the TERM.

	5.2
	LICENSEE
agrees to pay GTG *** upon execution of this AGREEMENT (the "PREPAYMENT"). The PREPAYMENT shall constitute a non-refundable credit against QUARTERLY LICENSE
ANNUITY payments required under this AGREEMENT. ***

	5.3
	All
payments required under this AGREEMENT shall be sent by electronic wire transfer to: 

Key
Bank

#307070267

1130 Haxton Drive

Fort Collins, Colorado 80525

Account: Genetic Technologies Limited

Account Number: 76009 000 2576 

	5.4
	LICENSEE
agrees to pay interest of *** per year or the maximum rate allowed by law, whichever is less, on fees payable but not paid to GTG when due.

	5.5
	MATERIAL
BREACH: A breach of any provision of this Article V or part thereof by LICENSEE shall be deemed a material breach. 

ARTICLE VI  

 WAIVER  

        No waiver by either party, express or implied, of any breach of any term, condition, or obligation of this AGREEMENT by the other party shall be construed as a
waiver of any subsequent breach of that term, condition, or obligation, or of any other term, condition, or obligation of this AGREEMENT of the same or different nature. 

ARTICLE VII  

 TERM AND TERMINATION OF AGREEMENT  

	7.1
	This
AGREEMENT shall be in effect for the TERM, unless terminated earlier as provided herein.

	7.2
	Either
party shall have the right to terminate this AGREEMENT upon any material breach of any term or condition of this AGREEMENT by the other party, which has not been corrected
within thirty (30) days after receipt of a notice in writing with reference to this Section 7.2 and such termination shall be without prejudice to any other rights or claims the
aggrieved party may have against the other party. GTG shall have the right to terminate this AGREEMENT upon written notice in the event that LICENSEE shall become involved in insolvency, dissolution,
bankruptcy, or receivership proceedings affecting the operation of LICENSEE's business, or in the event that LICENSEE discontinues business for any reason.

	7.3
	LICENSEE
shall have the right to terminate this AGREEMENT at any time by providing GTG with thirty (30) days written notice of such termination.

	7.4
	Termination
or expiration of this AGREEMENT shall not affect any obligation owed by LICENSEE to GTG prior to the termination or expiration. Upon termination or expiration of this
AGREEMENT:

	7.4.1
	all
licenses granted hereunder shall immediately cease. 

4

 

	7.4.2
	the
parties shall promptly return all CONFIDENTIAL INFORMATION and copies thereof of the other party to the other party or certify in writing that they have destroyed
all CONFIDENTIAL INFORMATION and copies thereof.

	7.4.3
	LICENSEE
shall pay GTG the pro-rated amount of the quarterly payment set forth in Section 5.1 that had accumulated as of the date of termination or
expiration for that year of the AGREEMENT.

	7.5
	SURVIVAL:
Articles II, III, VIII and X shall survive the termination or expiration of this AGREEMENT. 

ARTICLE VIII  

 CONFIDENTIALITY, PUBLICITY, PRESS RELEASES AND MARKING  

	8.1
	LIMITATIONS
ON USE AND DISCLOSURE: The parties agree that the terms and conditions set forth in this AGREEMENT are CONFIDENTIAL INFORMATION. The CONFIDENTIAL INFORMATION disclosed by
either party ("DISCLOSING PARTY") to the other party ("RECEIVING PARTY") constitutes the confidential and proprietary information of the DISCLOSING PARTY and the RECEIVING PARTY agrees to treat all
CONFIDENTIAL INFORMATION of the other in the same manner as it treats its own similar proprietary information, but in no case will the degree of care be less than reasonable care. The RECEIVING PARTY
shall use CONFIDENTIAL INFORMATION of the DISCLOSING PARTY only in performing under this AGREEMENT and shall retain the CONFIDENTIAL INFORMATION in confidence and not disclose to any third party
(except as authorized under this AGREEMENT) without the DISCLOSING PARTY's express written consent. The RECEIVING PARTY shall disclose the DISCLOSING PARTY's CONFIDENTIAL INFORMATION only to those
employees and contractors of the RECEIVING PARTY who have a need to know such information for the purposes of this AGREEMENT, and such employees and contractors must have entered into agreements with
the RECEIVING PARTY containing confidentiality provisions covering the CONFIDENTIAL INFORMATION, or similar confidential information, with terms and conditions at least as restrictive as those set
forth herein. Notwithstanding the foregoing, each party's confidentiality obligations hereunder shall not apply to information which as evidenced by written records:

	8.1.1
	is
already known to the RECEIVING PARTY, without an obligation of confidentiality, prior to disclosure by the DISCLOSING PARTY;

	8.1.2
	becomes
publicly available without fault of the RECEIVING PARTY;

	8.1.3
	is
rightfully obtained by the RECEIVING PARTY from a third party without restriction as to disclosure, or is approved for release by written authorization of the
DISCLOSING PARTY; or

	8.1.4
	is
developed independently by the RECEIVING PARTY without use of or access to the DISCLOSING PARTY's CONFIDENTIAL INFORMATION.

	8.2
	PERMITTED
USE AND DISCLOSURE: Each party hereto is permitted to disclose this AGREEMENT and use or disclose the CONFIDENTIAL INFORMATION disclosed to it by the other party:

	8.2.1
	To
the extent such use or disclosure is reasonably necessary in connection with complying with stock exchange rules; or

	8.2.2
	To
its legal and/or financial advisors, provided such advisors maintain the confidentiality of this AGREEMENT; or 

5

 

	8.2.3
	To
the extent such use or disclosure is reasonably necessary in prosecuting or defending litigation, complying with applicable law, governmental regulation or court
order, submitting information to tax or other governmental authorities, or otherwise exercising its rights hereunder; or

	8.2.4
	To
the extent necessary to enforce its rights under this AGREEMENT in connection with a legal proceeding or as required to be disclosed by law or governmental
regulation.

	8.2.5
	In
the instances set forth in this Sections 8.2.3 or 8.2.4, the RECEIVING PARTY shall provide reasonable advance written notice to DISCLOSING PARTY of such disclosure
and reasonably cooperate with the DISCLOSING PARTY in limiting such disclosure.

	8.3
	PUBLICITY
AND PRESS RELEASES: Neither party shall issue any press releases relating to this AGREEMENT without prior written approval of the other party; provided however, that:

	8.3.1
	Each
party shall be permitted to post a copy of or provide a link on its web site to any permitted disclosures made under this AGREEMENT;

	8.3.2
	Each
party may disclose the existence of the AGREEMENT only to the extent required to comply with any applicable law or regulation; and

	8.3.3
	LICENSEE
shall be able to disclose to SUBSIDIARIES of LICENSEE the existence of this AGREEMENT and the terms of this AGREEMENT, provided such SUBSIDIARIES maintain the
confidentiality of this AGREEMENT. 

ARTICLE IX  

 NOTICE  

	9.1
	Any
notice, request or statement hereunder shall be deemed to be sufficiently given or rendered when personally delivered, delivered by a major commercial rapid delivery courier
service or mailed by certified or registered mail, return receipt requested, and if given or rendered to LICENSEE, addressed to: 

Laboratory
Corporation of America Holdings

Attn: General Counsel

430 South Spring Street

Burlington, NC 27215

USA 

or,
if given or rendered to GTG, addressed to: 

Dr. Mervyn
Jacobson

Executive Chairman

Genetic Technologies Limited

60 Hanover Street

Fitzroy, Victoria 3065

Australia 

with
a copy to: 

Michael
A. DeSanctis, Esq.

Faegre & Benson LLP

3200 Wells Fargo Center

1700 Lincoln Street

Denver, CO 80203

USA 

6

 

or,
in any case, to such changed address or person as GTG or LICENSEE shall have specified to the other by written notice. 

ARTICLE X  

 REPRESENTATIONS AND WARRANTIES  

	10.1
	GTG
represents and warrants that it has the full right, power, and authority to enter into and perform its obligations under this AGREEMENT and grant to LICENSEE the license and
other rights as set forth herein, and there are no outstanding agreements, grants, licenses, encumbrances, liens, or agreements, either written or implied, inconsistent therewith or pursuant to which
this AGREEMENT or the parties' performance hereunder would violate, breach, or cause a default. GTG further represents and warrants that the LICENSED PATENTS are the only
patents owned or controlled by GTG that LICENSEE needs to practice the methods disclosed in the patents listed in Exhibit A.

	10.2
	The
execution, delivery, and performance of this AGREEMENT have been duly authorized by all necessary corporate actions on the part of GTG.

	10.3
	***

	10.4
	LICENSEE
represents and warrants that it has the full right, power, and authority to enter into and perform its obligations under this AGREEMENT, and there are no outstanding
agreements, grants, licenses, encumbrances, liens, or agreements, either written or implied, inconsistent therewith or pursuant to which this AGREEMENT or the parties' performance hereunder would
violate, breach, or cause a default.

	10.5
	LICENSEE
represents and warrants that the execution, delivery, and performance of this AGREEMENT have been duly authorized by all necessary corporate actions on the part of LICENSEE.

	10.6
	INDEMNIFICATION:

	10.6.1
	BY
LICENSEE: LICENSEE shall indemnify, hold harmless, and defend GTG, and GTG's SUBSIDIARIES, affiliates, officers, directors, representatives, employees, or agents
against any and all third party claims, causes of action, demands, judgments, settlements, expenses, or losses including, but not limited to, reasonable attorneys' fees and court costs arising out of
or in connection with: (i) any breach by LICENSEE of any representation, warranty, or covenant hereunder; (ii) the failure of LICENSEE to perform any covenants or obligations contained
in this AGREEMENT; or (iii) LICENSEE's negligent, reckless, or willful misconduct.

	10.6.2
	BY
GTG: GTG shall indemnify, hold harmless, and defend LICENSEE, and LICENSEE's SUBSIDIARIES, affiliates, officers, directors, representatives, employees, or agents
against any and all third party claims, causes of action, demands, judgments, settlements, expenses, or losses including, but not limited to, reasonable attorneys' fees and court costs arising out of
or in connection with: (i) any breach by GTG of any representation, warranty, or covenant hereunder; (ii) the failure of GTG to perform any covenants or obligations contained in this
AGREEMENT; or (iii) GTG's negligent, reckless, or willful misconduct.

	10.6.3
	The
indemnifying party's indemnification obligations under this Section 10.6 are conditioned upon the indemnified party (a) giving prompt notice of the
claim to the indemnifying party; (b) granting sole control of the defense or settlement of the claim or action to the indemnifying party; and (c) providing reasonable cooperation to the
indemnifying party and, at the indemnifying party's request and expense, assistance in the defense or settlement of the claim. 

7

 

	10.7
	DISCLAIMER
OF WARRANTIES: EXCEPT AS EXPRESSLY SET FORTH HEREIN, EACH PARTY EXPRESSLY DISCLAIMS, TO THE EXTENT ALLOWED BY APPLICABLE LAW, ANY AND ALL WARRANTIES OF ANY KIND, EXPRESS
OR IMPLIED, RELATING TO THE LICENSED PATENTS AND THE LICENSED SERVICES, INCLUDING WITHOUT LIMITATION THE WARRANTIES OF DESIGN, TITLE, MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE (EVEN IF
INFORMED OF SUCH PURPOSE), NONINFRINGEMENT OF THE INTELLECTUAL PROPERTY RIGHTS OF THIRD PARTIES, OR ARISING FROM A COURSE OF DEALING, USAGE OR TRADE PRACTICES, IN ALL CASES WITH RESPECT THERETO.

	10.8
	LIMITATION
OF LIABILITY: TO THE GREATEST EXTENT PERMISSIBLE UNDER APPLICABLE LAW, EXCEPT FOR A BREACH OF A PARTY'S OBLIGATIONS PURSUANT TO ARTICLE VIII, WITH RESPECT TO ANY CAUSE OF
ACTION RELATING TO OR ARISING FROM THIS AGREEMENT (WHETHER UNDER THIS ARTICLE X OR OTHERWISE): (I) NEITHER PARTY SHALL BE ENTITLED TO RECOVER FROM THE OTHER PARTY ANY SPECIAL, INCIDENTAL,
CONSEQUENTIAL OR PUNITIVE DAMAGES IN CONNECTION WITH THIS AGREEMENT OR ANY LICENSE GRANTED HEREUNDER, AND (II) NEITHER PARTY SHALL BE LIABLE FOR ANY AMOUNTS IN EXCESS OF THE TOTAL AMOUNTS PAID
TO GTG BY LICENSEE HEREUNDER DURING THE 12 MONTHS IMMEDIATELY PRECEDING THE EVENT GIVING RISE TO SUCH LIABILITY.

	10.9
	Nothing
contained in this AGREEMENT shall be construed as:

	10.9.1
	a
warranty or representation by GTG as to the validity or scope of any LICENSED PATENT except as provided expressly herein;

	10.9.2
	a
warranty or representation that any use or performance contemplated herein will be free from infringement of patents other than those LICENSED PATENTS under which
and to the extent to which licenses are in force hereunder;

	10.9.3
	an
agreement to bring or prosecute actions or suits against third parties for infringement or conferring any right to bring or prosecute actions or suits against
third parties for infringement;

	10.9.4
	conferring
any right to use by either party, in advertising, publicity, or otherwise, any trademark, trade name or name, or any contraction, abbreviation or
simulation thereof, of the other party;

	10.9.5
	conferring
by implication, estoppel or otherwise, upon LICENSEE, any license or other right under any intellectual property or patent, except that expressly granted
hereunder. 

ARTICLE XI  

 MISCELLANEOUS  

	11.1
	SERVICE
LITERATURE: To the extent practicable and consistent with LICENSEE's customary practices, LICENSEE will prominently display on any literature or other materials (in paper,
electronic or other format) distributed with or about any LICENSED SERVICES, as determined in LICENSEE's sole discretion, a notice indicating that any such LICENSED SERVICES are provided pursuant to a
license from GTG under the LICENSED PATENTS, which patents are owned by GTG.

	11.2
	CONSTRUCTION:
This AGREEMENT has been negotiated by the parties and their respective counsel. This AGREEMENT shall be interpreted fairly in accordance with its terms and without any
strict construction in favor of or against either party. This AGREEMENT shall not be 

8

 

construed
in favor or against either party by reason of the authorship of any provisions hereof. The existence or absence of any term or condition of this AGREEMENT shall not be used in the
construction or interpretation of any other agreement between the parties. 

	11.3
	MARKINGS:
To the extent practicable and consistent with LICENSEE's customary practices, LICENSEE shall use markings as GTG may reasonably request from time to time, including, but
not limited to, marking the LICENSED SERVICES and/or documentation related thereto with patent number(s) as determined in LICENSEE's sole discretion.

	11.4
	MODIFICATION:
This AGREEMENT sets forth the entire agreement and understanding between the parties as to the subject matter of this AGREEMENT and merges all prior discussions between
the parties, and no one of the parties shall be bound by any modification of this AGREEMENT, or by any conditions, definitions, warranties, or representations with respect to the subject matter of
this AGREEMENT, other than as expressly provided for herein, or as duly set forth on or subsequent to the EFFECTIVE DATE in writing and signed by duly authorized representatives of the party to be
bound thereby.

	11.5
	CHOICE
OF LAW: This AGREEMENT and matters connected with the performance thereof shall be construed, interpreted, applied and governed in all respects in accordance with the laws of
the State of Delaware (excluding conflicts of laws).

	11.6
	ASSIGNMENT.
Neither party may assign this AGREEMENT without the prior written consent of the other party except in the event of the sale of all or substantially all of a party's
capital stock, business or assets whether by merger or otherwise pertaining to the subject matter of this AGREEMENT, such party may assign this AGREEMENT to its successor and shall provide notice of
such assignment to the other party; provided however, that prior to any assignment permitted herein by LICENSEE, LICENSEE's successor must expressly assume in writing LICENSEE's obligations under this
AGREEMENT and expressly acknowledge in writing that products and services of such successor existing prior to such assignment shall not be LICENSED SERVICES.

	11.7
	ATTORNEYS'
FEES: Upon resolution of any claim or controversy arising under this AGREEMENT, the prevailing party shall be awarded its reasonable attorneys' fees and costs in addition
to any other amount awarded.

	11.8
	EQUITABLE
REMEDIES: Each party acknowledges that its breach of any of its obligations set forth in Article VIII could result in immediate and irreparable damage to the other
party and that no adequate remedy may exist at law. Each party acknowledges and agrees that the other party may seek any available remedy, whether in law or equity, upon the other party's breach of
any of its obligations set forth in Article VIII.

	11.9
	INDEPENDENT
BUSINESS: The parties acknowledge that their business operations are completely independent and nether party shall at any time hold itself out as an agent or
representative of the other party. No partnership, joint venture, or other relationship shall be deemed to exist by virtue of this AGREEMENT.

	11.10
	INDEPENDENT
TERMS: All the terms of this AGREEMENT shall be independent and unconditional so that the performance of any one term shall not be subject to any set off or
counterclaim.

	11.11
	SEVERABILITY:
In the event any clause or term of this AGREEMENT is determined to be void, invalid, or unenforceable, the clause shall be reformed to the extent necessary in order to
overcome the limitation and give effect to the original intent of the parties and economic effect of the original provision and, as revised this AGREEMENT shall remain in full force and effect. 

9

 
	11.12
	HEADINGS:
The headings contained within this AGREEMENT are for convenience and reference purposes only. They do not form a part hereof and shall not affect the meaning or
interpretation of this AGREEMENT.

	11.13
	FURTHER
ASSURANCES: The parties hereto shall execute such further documents and perform such further acts as may be necessary to comply with the terms of this AGREEMENT and
consummate the transactions herein provided.

	11.14
	FORCE
MAJEURE: Neither party shall be held responsible if the fulfillment of any terms or provisions of this AGREEMENT are delayed or prevented by wars, revolutions, fires, floods,
acts of God, acts of terrorism whether actual or threatened, or other causes similar to those enumerated and not within the control of the party whose performance is interfered with, and which by the
exercise of reasonable diligence, the party is unable to prevent.

	11.15
	COUNTERPARTS:
This AGREEMENT may be executed in counterparts (and evidenced by facsimile signatures), each of which will be deemed an original and all of which together constitute
one instrument. 

[REMAINDER
OF PAGE INTENTIONALLY LEFT BLANK] 

10

 

        IN
WITNESS WHEREOF, the parties hereto have caused their authorized representatives to execute this AGREEMENT. 

	

GTG:	
 	

LICENSEE:
	 	 	 	 	 	 	 
	GENETIC TECHNOLOGIES LIMITED	 	LABORATORY CORPORATION OF AMERICA HOLDINGS
	 	 	 	 	 	 	 
	By:	 	 	 	By:	 	 
	 	 	
	 	 	 	

	 	 	 	 	 	 	 
	
 Printed Name/Date	 	
 Printed Name/Date
	 	 	 	 	 	 	 
	
 Title	 	 	 	 
	 	 	 	 	
 Title

11

 
Exhibit A

Licensed Patents  

        United States Patent No. 5,192,659 

        United
States Patent No. 5,612,179 

        United
States Patent No. 5,789,568 

        United
States Patent No. 5,851,762 

        United
States Patent No. 5,096,557 

[REMAINDER
OF PAGE INTENTIONALLY LEFT BLANK] 

12

QuickLinks

Exhibit 4.11

LICENSE AGREEMENTQuickLinks
 -- Click here to rapidly navigate through this document

 
 

Exhibit 4.12    
    

Clayton Utz  

Settlement and Licence Agreement  

Genetic Technologies Limited

ACN 009 212 328  

C Y O'Connor ERADE Village Foundation incorporating the Immunogenetics Research Foundation and the Institute of
Molecular Genetics and Immunology Incorporated
  (ABN 67 161 830 965) 

 

If
you have any questions about the details of this document
 please contact Vince Annetta on + 61 3 9286 6000  

Clayton Utz

Lawyers

Level 18 333 Collins Street Melbourne VIC 3000 Australia

DX 38451 333 Collins VIC

T + 61 3 9286 6000 F + 61 3 9629 8488 

www.claytonutz.com  

Our reference 160/385/31720916 

 

Table of Contents  

       

i

   Settlement and Licence Agreement made at                        on

	
Parties	
 	

Genetic Technologies Limited (ACN 009 212 328) of 60-66 Hanover Street, Fitzroy in the State of Victoria (Licensor)
	

 	
 	
C Y O'Connor ERADE Village Foundation incorporating the Immunogenetics Research Foundation and the Institute of Molecular Genetics and Immunology Incorporated (ABN 67 161 830 965) (formerly
known as Immunogenetics Research Foundation of WA Inc.) of Cnr Nicholson and Warton Roads, Canning Vale in the State of Western Australia (Licensee)

Recitals  

	A.
	The
Licensor will after the Effective Date own the Foundation IP.

	B.
	The
Licensee and the Licensor entered into the Heads of Agreement by which (among other things):

	(a)
	the
Licensor agreed to grant certain licences in relation to the GTG IP and the Sub-Licensable GTG IP; and

	(b)
	the
parties agreed to mutually release each other in relation to any claims each may have against the other for or in relation to any infringement of the IP owned by a party which
occurred before the date of the Heads of Agreement.

	
C.
	The
 parties now desire to enter into this Settlement and Licence Agreement contemplated in the Heads of Agreement. 

This agreement provides  

	1.
	Definitions and interpretation

	1.1
	Definitions

Adjustment Events has the meaning given to it in the GST Legislation. 

ASX means Australia Stock Exchange Limited (ACN 008 624 691). 

Claim means any action, suit, demand, proceeding, claim for Loss or any other form of claim, whether based in contract, tort (including, without
limitation, negligence), misrepresentation, breach of warranty or on any other statutory, legal or equitable grounds. 

Confidential Information means all information in any form (including Documents and things in electronic, magnetic, digital and other intangible forms,
whether capable of being read by human beings or not) relating to any of the business, products, IP, research, development, customers, licensees and suppliers of a party and any and all other
information of any nature and in any form (including Documents and things in electronic, magnetic, digital and other intangible forms, whether capable of
being read by human beings or not) that is designated by a party as being confidential or is confidential having regard to its nature or the context in which it was disclosed. For the purposes of this
agreement Confidential Information of the Licensor includes information relating to the GTG IP and the Sub-Licensable GTG IP. 

Consequential Loss means any loss or damage suffered by the Licensor: 

	(a)
	which
is indirect or consequential;

	(b)
	which
results from some special circumstance or supervening event; 

1

 

	(c)
	which
is by way of loss of revenue, loss of profits, loss of goodwill or credit, loss of business reputation, future reputation or publicity, loss of use, loss of interest, damage to
credit rating, loss or denial of opportunity, or increased overhead costs, production or other downtime or which relates to expenses caused by the breach or outgoings rendered futile by the breach;

	(d)
	which
is not an immediate result of the breach by the Licensee of this agreement or any other obligation;

	(e)
	which
is suffered by the Licensor as a result of a claim upon it by another person; or

	(f)
	which
consists of a claim for personal injury or damage to property. 

Improvement means any IP which: 

	(a)
	is
based on or incorporates any of the GTG IP which is created or developed after the Effective Date and which is capable of protection as a registered patent or by some other form of
registrable intellectual property; and

	(b)
	is
discrete from the GTG IP to which that IP may relate. 

IP Sale and Royalty Agreement means the IP Sale and Royalty Agreement to be executed by the parties in accordance with the Heads of Agreement. 

Loss means any damage, loss (including Consequential Loss), liability, cost, charge, expense, outgoing or payment (whether present, contingent,
unascertained, immediate, future, indirect, incidental or otherwise). 

Public Good Licensee means any person to whom a licence is granted in accordance with clause 0. 

Purpose means conducting research and development work in the Territory in the fields of any of genetics and genomics. 

Term means the period from the Effective Date until termination of this agreement in accordance with clause 0. 

Territory means the State of Western Australia. 

	1.2
	Interpretation

In
this agreement: 

	(a)
	headings
are for convenience only and do not affect interpretation; 

and
unless the context indicates a contrary intention: 

	(b)
	the
expression person includes an individual, the estate of an individual, a corporation, an authority, an association or a joint
venture (whether incorporated or unincorporated), a partnership and a trust;

	(c)
	a
reference to any statute or to any statutory provision includes any statutory modification or re-enactment of it and any statutory provision substituted for it, and all
ordinances, by-laws, regulations, rules and statutory instruments (however described) issued under it;

	(d)
	a
reference to any party includes that party's executors, administrators, successors and permitted assigns, including any person taking by way of permitted novation;

	(e)
	a
reference to any document (including this agreement) is to that document as varied in accordance with its terms, novated in accordance with its terms, ratified or replaced from time
to time; 

2

 

	(f)
	words
importing the singular include the plural (and vice versa), and words indicating a gender include every other gender;

	(g)
	references
to parties, clauses or schedules are references to parties, clauses and schedules to or of this agreement, and a reference to this agreement includes any schedule to this
agreement;

	(h)
	where
a word or phrase is given a defined meaning, any other part of speech or grammatical form of that word or phrase has a corresponding meaning;

	(i)
	the
word "includes" in any form is not a word of limitation;

	(j)
	a
reference to "$" or "dollar" is to Australian currency;

	(k)
	where
the day on or by which a thing is to be done is not a Business Day, that thing must be done on or by the next Business Day; and

	(l)
	words
and phrases which are defined in the IP Sale and Royalty Agreement have the same meaning when used in this agreement.

 

	2.
	Condition Precedent

Clauses
0 to 0 of this agreement will not become binding on, nor grant any rights to or impose any obligations on, either party unless the IP Sale and Royalty Agreement and the Sponsored Research
Agreement are executed by all parties on or before the Effective Date or such other date as the parties may agree in writing. 

	3.
	Licence of GTG IP

	3.1
	Grant of licence to the Licensee

Subject
to clauses 0 and 0, the Licensor by this agreement grants to the Licensee during the Term an irrevocable and continuing non-exclusive licence to use (without a right to
sub-licence the use of): 

	(a)
	the
GTG IP; and

	(b)
	subject
to clause 0, the Sub-Licensable GTG IP, 

for
the Purpose. 

	3.2
	Conditions precedent to licence of Sub-Licensable GTG IP

The
licence in clause 00 for the Licensee to use the Sub-Licensable GTG IP is subject to the conditions precedent that: 

	(a)
	before
the Licensee commences using any IP pursuant to clause 00, it first sends a written request to the Licensor asking whether the IP that the Licensee wishes to use is
Sub-Licensable GTG IP and receives written confirmation (which must not be unreasonably delayed) from the Licensor that the IP is Sub-Licensable GTG IP;

	(b)
	the
Licensee pays all costs incurred by any of the Licensor and any Related Body Corporate of the Licensor as a direct or indirect result of the Licensee using any of the
Sub-Licensable GTG IP under such licence. If the Licensee fails or refuses to pay any such costs, the licence referred to in clause 00 will be void ab
initio with respect to each of the items of Sub-Licensable GTG IP to which such failure or refusal by the Licensee relates. The Licensee must within 5 Business Days
after the end of each calendar month provide the Licensor with all information reasonably requested by the Licensor from time to time (including any information that the Licensor requires to determine
what costs are payable by it) regarding the Licensee's use of the Sub-Licensable GTG IP during that calendar month. The Licensee 

3

 

must
pay to the Licensor any amounts requested by the Licensor to be paid in accordance with this clause 00 within 5 Business Days after the Licensee receives a Tax Invoice for that amount; and 

	(c)
	the
Licensee uses the Sub-Licensable GTG IP solely for the Purpose.

 

	3.3
	Grant of licence to persons nominated by the Licensee

	(a)
	The
Licensor agrees that, in consideration of the payment of $1,000 by each person to whom a licence is to be granted in accordance with this clause 0, it will grant to
academic and public health institutions in the Territory nominated by the Licensee and approved by the Licensor (such approval not to be unreasonably withheld), including:

	(i)
	the
Health Department of Western Australia; and

	(ii)
	the
University of Western Australia, 

a
non-exclusive licence (on terms reasonably required by GTG) during the Term to use (without a right to sub-licence the use of) the GTG IP for the Purpose and for similar
non-commercial applications in the Territory. 

	(b)
	The
Licensee acknowledges and agrees that:

	(i)
	nothing
in this agreement gives it any right to sub-licence any of the GTG IP or the Sub-Licensable GTG IP, including to any person referred to in
clause 00; and

	(ii)
	the
Licensor is not by clause 00 or any other part of this agreement required to grant to any person any licence or sub-licence for that person:

	A.
	to
use or exploit any of the GTG IP for commercial purposes; or

	B.
	(other
than the Licensee) to use or exploit any of the Sub-Licensable GTG IP for any purpose.

 

	3.4
	Conditions applicable to licences

The
licence granted by clause 0 and all licences granted by the Licensor in accordance with clause 0 are and will be granted on the conditions that: 

	(a)
	the
GTG IP and (in the case of the Licensee) the Sub-Licensable GTG IP:

	(i)
	can
only be used for the Purpose and (in the case of Public Good Licensees) for similar non-commercial applications in the Territory;

	(ii)
	can
not be used for any purpose that results in products or services based on or incorporating the GTG IP or the Sub-Licensable GTG IP being used or available outside the
Territory;

	(iii)
	can
not be sub-licensed by the Licensee or Public Good Licensees;

	(iv)
	can
not be used in a way that infringes the IP or other rights of any other person;

	(v)
	can
only be used in accordance with the terms of the agreement by which the licence is granted and any reasonable directions given from time to time by the Licensor regarding use of
any of the GTG IP and the Sub-Licensable GTG IP (provided that such directions are not inconsistent with the terms of this agreement); and 

4

 

	(b)
	the
Licensee and each Public Good Licensee:

	(i)
	must
refer to the Licensor any request relating to the GTG IP or the Sub-Licensable GTG IP which is outside the scope of its licence (by way of example only and without
limitation, where a person wants to be granted a licence to use the GTG IP);

	(ii)
	must
not challenge, contest, oppose or question directly or indirectly any of:

	A.
	the
validity of the Licensor's or any other person's right, title and interest in and to the GTG IP and the Sub-Licensable GTG IP (including the IP and other rights in the
GTG IP and the Sub-Licensable GTG IP);

	B.
	the
Licensor's or any other person's ownership of any application for or registration of any of the GTG IP and the Sub-Licensable GTG IP; and

	C.
	any
application for or registration of any of the GTG IP and the Sub-Licensable GTG IP.

	(iii)
	must
agree to assign to the Licensor in accordance with clause 0 the IP they create or develop during the Term which is an improvement in, addition to, modification of, based
on or incorporates any of the GTG IP and the Sub-Licensable GTG IP.

 

	3.5
	Limitations on licences

The
Licensor acknowledges and agrees that: 

	(a)
	the
licence granted to the Licensee in clause 0 and the licences to be granted by to Public Good Licensees in accordance with clause 0 are irrevocable and continuing
during the Term; and

	(b)
	the
strategic alliance between the Licensor and the Licensee (as reflected in this agreement, the Heads of Agreement, the Sponsored Research Agreement and the IP Sale and Royalty
Agreement) is a high priority for the Licensor in the Territory, and the Licensor does not currently intend to grant to any other person a licence to use or exploit any of the GTG IP in the Territory. 

For
the avoidance of doubt, nothing in this agreement prevents the Licensor granting or restricts the discretion of the Licensor in granting to another person a licence to use and exploit the GTG IP
in the Territory if the Licensor reasonably believes that it is in the best interests of the Licensor to do so. 

	4.
	Release

	4.1
	Background

The
parties have for a number of years conducted research and development work (whether themselves or through their Related Bodies Corporate) in comparable fields of scientific endeavour. Their
respective areas of endeavour may have overlapped and may lead to conflicting claims. 

	4.2
	Release by Licensee

The
Licensee by this agreement releases and forever discharges: 

	(a)
	the
Licensor;

	(b)
	each
Related Body Corporate of the Licensor;

	(c)
	each
licensee of any of the Licensor and any Related Body Corporate of the Licensor;

	(d)
	each
officer, employee and agent of any person referred to in clauses 00 to 00; and 

5

 

	(e)
	the
successors and permitted assigns of any person referred to in clauses 00 to 00, 

from
all and any Claims which any of the Licensee and any Related Body Corporate of the Licensee now have or but for this agreement could or might have had against any of them relating to, arising out
of or in connection with any of the infringement and misuse of the IP or other rights of any of the Licensee and any Related Body Corporate of the Licensee at any time before the date of the Heads of
Agreement. 

	4.3
	Release by Licensor

The
Licensor by this agreement releases and forever discharges: 

	(a)
	the
Licensee;

	(b)
	each
Related Body Corporate of the Licensee;

	(c)
	each
licensee of any of the Licensee and any Related Body Corporate of the Licensee;

	(d)
	each
officer, employee and agent of any person referred to in clauses 00 to 00; and

	(e)
	the
successors and permitted assigns of any person referred to in clauses 00 to 00, 

from
all and any Claims which any of the Licensor and any Related Body Corporate of the Licensor now have or but for this agreement could or might have had against any of them relating to, arising out
of or in connection with any of the infringement and misuse of the IP or other rights of any of the Licensor and any Related Body Corporate of the Licensor at any time before the date of the Heads of
Agreement. 

	4.4
	Plea in bar

This
agreement can be pleaded by each party and its Related Bodies Corporate and their officers, employees, agents, licensees, successors and permitted assigns in bar to any Claim relating to, arising
out of or in connection with any of the infringement and misuse of the IP or other rights of the other party. 

	4.5
	No admissions

Each
party acknowledges and agrees that the inclusion of the release in this agreement is not an admission by either party of liability or the amount of any liability. 

	5.
	Consideration by Licensee

In
consideration of: 

	(a)
	the
licence granted to the Licensee by clause 0;

	(b)
	the
Licensor agreeing to grant licences to Public Good Licensees in accordance with clause 0;

	(c)
	the
Licensor agreeing to the other terms of the strategic alliance between the Licensor and the Licensee (as reflected in this agreement, the Heads of Agreement, the Sponsored
Research Agreement and the IP Sale and Royalty Agreement); and

	(d)
	the
release granted by the Licensor in clause 0, 

the
Licensee: 

	(e)
	will
pay to the Licensor on the Effective Date a licence fee of $2,500,000 (two million five hundred thousand dollars Australian currency);

	(f)
	grants
the release granted by the Licensee in clause 0; and

	(g)
	otherwise
accepts and agrees to comply its obligations under this agreement. 

6

 

For
the avoidance of doubt, if the Licensee notifies the Licensor in accordance with clause 7.2(a)(ii) of the IP Sale and Royalty Agreement that it wishes to pay the licence fee that the
Licensee is required to pay under clause 00 of this agreement by reducing the number of Shares which the Licensor is required to issue to the Licensee or its nominee under the IP Sale and
Royalty Agreement and the Licensor issues to the Licensee or to the Licensee's nominee 16,666,667 (sixteen million, six hundred and sixty six thousand, six hundred and sixty seven) Shares, then after
the Effective Date the Licensee has no further obligation to the Licensor to pay the licence fee specified in clause 00 of this agreement. 

	6.
	IP

	6.1
	Ownership of Improvements

	(a)
	All
Improvements created or developed during the Term by:

	(i)
	the
Licensee (other than Improvements created or developed by or on behalf of the Licensee under in accordance with the Sponsored Research Agreement or in accordance with another
agreement between the Licensor or a Related Body Corporate of the Licensor and the Licensee or a Related Body Corporate of the Licensee); or

	(ii)
	any
Public Good Licensees, 

will
be owned by the Licensee or the Public Good Licensee who creates or develops the Improvement. 

	(b)
	Subject
to clause 00, prior to offering to any person any right to license, acquire, commercialise, deploy, exploit or apply any IP owned by the Licensee in accordance with
clause 00, the Licensee must first offer that right to the Licensor on reasonable terms and give the Licensor thirty Business Days to accept the offer.

	(c)
	If
the Licensor does not accept or rejects an offer made by the Licensee under clause 00, the Licensee may for a period of thirty Business Days offer the relevant right to
other persons on the same terms as those offered to, and not accepted or rejected by, the Licensor. If the Licensee does not grant the right to any other person during that thirty Business Day period,
or wishes to grant the right on terms not the same as the terms on which that right was offered to the Licensor, the Licensee must not offer or grant the relevant right to any other person without
again first complying with the procedure in clause 00 and this clause 00.

	(d)
	Clause 00
does not apply to the extent that the Improvement was created or developed by the Licensee as a result of or in the course of any research and development carried out
by the Licensee that was funded by another person and it is a condition of such funding that the Licensee can not grant a right of first refusal in relation to the IP arising from that research and
development.

 

	6.2
	Ownership of GTG IP and Sub-Licensable GTG IP

	(a)
	Nothing
in this agreement grants to:

	(i)
	the
Licensee; or

	(ii)
	any
Public Good Licensees, 

any
right, title or interest in or to any of the GTG IP and the Sub-Licensable GTG IP except to the extent that they are granted an express licence under clause 0 or an express
licence in accordance with clause 0. 

	(b)
	For
the avoidance of doubt, the ownership by the Licensee or a Public Good Licensee of an Improvement does not grant them any right, title or interest in or to any of the GTG IP and 

7

 

the
Sub-Licensable GTG IP on which the Improvement may be based or which it may incorporate. 

	6.3
	Ownership of other IP

	(a)
	Subject
to clause 0, the Licensor will own all IP created or developed during the Term by:

	(i)
	the
Licensee; or

	(ii)
	any
Public Good Licensees, 

which
is an improvement in, addition to, modification of, based on or incorporates any of the GTG IP and the Sub-Licensable GTG IP. 

	(b)
	The
Licensee must, and must make sure that all Public Good Licensees, promptly after its creation and otherwise on reasonable written request by the Licensor disclose to the Licensor
any IP referred to in clause 00 and deliver to the Licensor all Documents relating to that IP.

	(c)
	The
Licensee must, and must make sure that all Public Good Licensees, execute all further documents and do all further things (at the reasonable cost of the Licensor) which the
Licensor reasonably requires to perfect, record or confirm the Licensor's right, title and interest in and to the IP referred to in clause 00.

	(d)
	The
Licensee:

	(i)
	must;

	(ii)
	must
use its best endeavours to make sure that the Licensee's officers, employees and agents; and

	(iii)
	must
use its best endeavours to make sure that all Public Good Licensees and the officers, employees and agents of Public Good Licensees, 

provide
all information and assistance (at the reasonable cost of the Licensor) reasonably requested by the Licensor to: 

	(iv)
	make
any application for;

	(v)
	prosecute
any application for registration of;

	(vi)
	defend
any opposition to any application for registration of;

	(vii)
	defend
any application to cancel or invalidate any registration for; and

	(viii)
	take
action in relation to any infringement of any registration of, 

any
of IP referred to in clause 00. 

	(e)
	The
Licensee:

	(i)
	must
not;

	(ii)
	must
use its best endeavours to make sure that the Licensee's officers, employees and agents do not; and

	(iii)
	must
use its best endeavours to make sure that Public Good Licensees and the officers, employees and agents of Public Good Licensees do not, 

challenge,
contest, oppose or question directly or indirectly any of: 

	(iv)
	the
validity of the Licensor's right, title and interest in and to the IP referred to in clause 00; 

8

 

	(v)
	the
Licensor's ownership of any application for or registration of any of the IP referred to in clause 00; and

	(vi)
	any
application for or registration of any of the IP referred to in clause 00.

 

	7.
	Warranties

	7.1
	Mutual warranties

Each
party warrants to the other that, to the best of that party's knowledge, it is the only person that has any Claim against the other party in respect of the subject matter of the release granted
to the other party by clause 0. 

	7.2
	Warranty by Licensor

	(a)
	The
Licensor warrants and represents to the Licensee that, to the best of the Licensor's knowledge, it owns all rights in the letters patent and patent applications which comprise the
Other GTG IP.

	(b)
	Except
as set out in clause 00, the Licensor does not provide any warranties to the Licensee in relation to the GTG IP or the Sub-Licensable GTG IP, including any
warranties relating to:

	(i)
	the
validity of any of the GTG IP and the Sub-Licensable GTG IP;

	(ii)
	the
Licensor's ownership of the GTG IP;

	(iii)
	any
other person's ownership of the Sub-Licensable GTG IP;

	(iv)
	whether
use or exploitation of any of the GTG IP and the Sub-Licensable GTG IP infringes the IP or other rights of any other person; and

	(v)
	the
suitability of any of the GTG IP and the Sub-Licensable GTG IP for any purpose.

 

	7.3
	Warranty by Licensee

	(a)
	The
Licensee warrants and represents to the Licensor that but for clause 0 it would upon its creation own all rights in the IP referred to in clause 0.

	(b)
	Except
as set out in clause 00, the Licensee and the Public Good Licensees do not provide any warranties to the Licensor in relation to any IP owned by the Licensor in
accordance with clause 0, including any warranties relating to:

	(i)
	the
validity of any of the IP owned by the Licensor in accordance with clause 0;

	(ii)
	the
Licensee's ownership upon its creation, apart from the assignment in accordance with clause 0, of the IP referred to in clause 0;

	(iii)
	whether
use or exploitation of any IP owned by the Licensor in accordance with clause 0 infringes the IP or other rights of any other person; and

	(iv)
	the
suitability of any IP owned by the Licensor in accordance with clause 0 for any purpose.

 

	7.4
	Exclusion of warranties

	(a)
	To
the full extent permitted by the laws of the Commonwealth of Australia and any State or Territory of Australia having jurisdiction, the Licensor by this agreement excludes all
implied warranties in relation to the GTG IP and the Sub-Licensable GTG IP.

	(b)
	To
the full extent permitted by the laws of the Commonwealth of Australia and any State or Territory of Australia having jurisdiction, the Licensee by this agreement excludes all
implied warranties in relation to any IP owned by the Licensor in accordance with clause 0. 

9

 

	7.5
	Non-excludable terms

Where
any laws of the Commonwealth of Australia or any State or Territory of Australia having jurisdiction imply a term, condition or warranty into this agreement or any relationship created by this
agreement between the Licensor and the Licensee or otherwise gives the Licensee or the Licensor a particular remedy against the Licensor or the Licensee respectively, the application of, exercise of
or liability under which cannot be excluded, then the liability of the Licensor or the Licensee (as the case may be) for any breach of such implied term, condition or warranty or under such remedy
will be limited at the option of the party on whom the liability is imposed in any one or more of the ways permitted by that legislation including, where so permitted: 

	(a)
	if
the breach relates to goods:

	(i)
	the
replacement of those goods or the supply of equivalent goods;

	(ii)
	the
repair of those goods;

	(iii)
	the
payment of the cost of replacing those goods or acquiring equivalent goods; or

	(iv)
	the
payment of the costs of having those goods repaired; and

	(b)
	if
the breach relates to services:

	(i)
	the
supplying of those services again; or

	(ii)
	the
payment of the cost of having those services supplied again.

 

	8.
	Indemnity

	8.1
	Indemnity by Licensor

The
Licensor indemnifies the Licensee and all of the Licensee's officers, employees, agents and Related Bodies Corporate against any liability or cost which the Licensee or any of the Licensee's
officers, employees, agents or Related Bodies Corporate incur concerning, arising out of or in consequence of any Claim by any person arising from: 

	(a)
	any
act or omission by the Licensor arising from the performance of the Licensor's rights or obligation under this agreement; and

	(b)
	any
breach of this agreement (including any warranty given or representation made in this agreement) by the Licensor.

 

	8.2
	Indemnity by Licensee

The
Licensee indemnifies the Licensor and all of the Licensor's officers, employees, agents and Related Bodies Corporate against any liability or cost which the Licensor or any of the Licensor's
officers,
employees, agents or Related Bodies Corporate incur concerning, arising out of or in consequence of any Claim by any person arising from: 

	(a)
	any
act or omission by the Licensee arising from the performance of the Licensee's rights or obligation under this agreement; and

	(b)
	any
breach of this agreement (including any warranty given or representation made in this agreement) by the Licensee.

 

	8.3
	Mutual indemnity

Each
party by this agreement indemnifies and agrees in future to indemnify any of the other party and the Related Bodies Corporate of the other party and their officers, employees, agents, 

10

 

licensees,
successors and permitted assigns from and against all Claims which that party, any Related Body Corporate of that party and any person claiming under or by virtue of that party: 

	(a)
	has
now;

	(b)
	had
at any time before the execution of this agreement; or

	(c)
	but
for the execution of this agreement may have had or may have been able to bring, make or claim, 

against
any of the other party and the Related Bodies Corporate of the other party and their officers, employees, agents, licensees, successors and permitted assigns relating to, arising out of or in
connection with any of the infringement and misuse of IP or other rights of the party before the date of the Heads of Agreement. 

	9.
	GST

	(a)
	Where
a party (Supplier) makes a Taxable Supply under or in connection with this agreement or in connection with any matter or thing
occurring under this agreement to the other party (Recipient) and the consideration otherwise payable for the Taxable Supply does not include GST the
Supplier will be entitled, in addition to any other consideration recoverable in respect of the Taxable Supply, to recover from the Recipient the amount of any GST on the Taxable Supply.

	(b)
	If
the amount paid by the Recipient to the Supplier in respect of GST differs from the GST on the Taxable Supply (taking into account any Adjustment Events that occur in relation to
the Taxable Supply), an adjustment shall be made. If the amount paid by the Recipient exceeds the GST on the Taxable Supply, the Supplier shall refund the excess to the Recipient. If the amount paid
by the Recipient is less than the GST on the Taxable Supply, the Recipient shall pay the deficiency to the Supplier.

	(c)
	Where
a party is entitled, under or in connection with this agreement or in connection with any matter or thing occurring under this agreement, to recover all or a proportion of its
costs or is entitled to be compensated for all or a proportion of its costs, the amount of the recovery or compensation shall be reduced by the amount of (or the same proportion of the amount of) any
Input Tax Credits available in respect of those costs.

	(d)
	A
party will not be obliged to pay any amounts to the other party unless and until a valid Tax Invoice has been issued by the other party and is received by the party. Each party
agrees to do all things, including providing invoices or other documentation, that may be necessary or desirable to enable or assist another party to:

	(i)
	claim
Input Tax Credits to the maximum extent possible; or

	(ii)
	reduce
the amount recoverable from that other party under any indemnity or cost recovery provided for in this agreement.

 

	10.
	Infringement

	10.1
	Notification of infringement

If
the Licensee or a Public Good Licensee: 

	(a)
	becomes
aware of a Claim by a person that use by the Licensee or a Public Good Licensee of any of the GTG IP and the Sub-Licensable GTG IP infringes or amounts to a misuse
of the IP or any other rights of that person; or

	(b)
	believes
that a person is infringing or misusing any of the IP or other rights in or relating any of the GTG IP and the Sub-Licensable GTG IP, 

11

 

the
Licensee must promptly provide a written notice to the Licensor setting out details of the alleged Claim. 

	10.2
	Defence of Claims

	(a)
	In
the circumstances set out in clause 0 it will be in the discretion of the Licensor whether to defend, settle or compromise the Claim.

	(b)
	The
Licensee will be solely responsible for all Loss in respect of a Claim where the Claim solely relates to, arises out of or in connection with:

	(i)
	GTG
IP which was developed or created by the Licensee or a Public Good Licensee, whether before or after the Effective Date;

	(ii)
	use
of any of the GTG IP and the Sub-Licensable GTG IP which is not in accordance with the terms of this agreement or any reasonable directions given from time to time by
the Licensor regarding use of any of the GTG IP and the Sub-Licensable GTG IP.

	(c)
	Each
party must (at the reasonable cost of the other party) provide to the other party all reasonable assistance required by the other party in respect of the conduct of any defence
of a Claim.

 

	10.3
	Infringement or misuse action by Licensor

	(a)
	In
the circumstances set out in clause 0 the Licensor may elect to take legal action in respect of the infringement or misuse or settle or compromise its claim against the
infringer.

	(b)
	The
Licensor will be solely responsible for all costs in respect of any legal action which it takes against an infringer.

	(c)
	The
Licensor may (with the prior written consent of the Licensee, which must not be unreasonably withheld or delayed) bring such action in the name of the Licensee or join the
Licensee as a party to such action.

	(d)
	The
Licensor will be entitled to the benefit of all orders (including any monetary award, damages, account of profits or costs) which are made as a result of such action and to all
amounts paid to or at the direction of the Licensor as part of any settlement or compromise of a claim.

	(e)
	If
the Licensor elects to take legal action against the infringer, the Licensee must (at the Licensor's cost) provide to the Licensor all reasonable assistance required by the
Licensor in respect of the conduct of such action.

 

	11.
	Insurance

The
Licensee must co-operate and must make sure that the Public Good Licensees co-operate with the insurers of the Licensor in the investigation of all Claims made which fall
within the risks covered by any insurances held by the Licensor. 

	12.
	Termination

	12.1
	Termination by Licensor

	(a)
	The
Licensor may immediately terminate this agreement if the Licensee breaches or defaults under the licence granted to it (including by breaching any of the conditions of licence
specified in clause 0).

	(b)
	For
the avoidance of doubt, termination by the Licensor of this agreement does not of itself give the Licensor a right to terminate the licence granted to a Public Good Licensee
before termination of this agreement. 

12

 

	12.2
	Termination by either party

Either
party may terminate this agreement immediately if the other party: 

	(a)
	breaches
a material term of this agreement and fails to remedy that breach within ten Business Days after receiving a notice from the terminating party requiring the other party to
remedy the breach; or

	(b)
	goes
into liquidation, has a receiver, receiver and manager, administrator or similar person appointed, enters into a scheme of arrangement with creditors or is unable to pay its
debts as and when they fall due.

 

	12.3
	Termination of other agreements

If
any of: 

	(a)
	the
Sponsored Research Agreement; and

	(b)
	the
IP Sale and Royalty Agreement, 

is
terminated, either party may terminate this agreement by giving ten Business Days' notice in writing to the other party. 

	12.4
	Consequences of termination

Clauses
0, 0, 00, 00, 00, 0, 00, 00, 0 and this clause 0 survive termination of this agreement to the extent they operated immediately before termination of this agreement. 

	12.5
	Termination of licence to Public Good Licensee

If
a Public Good Licensee: 

	(a)
	breaches
or defaults under the agreement by which it is granted a licence to use the GTG IP; or

	(b)
	goes
into liquidation, has a receiver, receiver and manager, administrator or similar person appointed, enters into a scheme of arrangement with creditors or is unable to pay its
debts as and when they fall due, 

the
Licensor may by notice in writing to that Public Good Licensee immediately terminate the agreement by which that Public Good Licensee is granted a licence to use the GTG IP. After receipt of such
notice the Public Good Licensee will need to cease using the GTG IP within twenty Business Days. 

	13.
	Confidentiality

	13.1
	Obligation of confidentiality

Each
party must treat as confidential and must make sure that any person to whom it discloses in accordance with this agreement treats as confidential: 

	(a)
	all
information in relation to this agreement; and

	(b)
	any
Confidential Information of the other party, 

and
must not: 

	(c)
	use
such information; and

	(d)
	disclose
such information except:

	(i)
	to
its officers, employees, professional advisers and auditors; and 

13

 

	(ii)
	after
those people have:

	A.
	been
informed that the information is confidential, must not be used except for the purpose for which it was provided to them by the party and must not be further disclosed by the
officer, employee, professional adviser or auditor; and

	B.
	signed
(whether before or after the Effective Date) a deed of confidentiality in favour of the other party in terms reasonably agreed between the parties (acting reasonably).

 

	13.2
	Return of information

	(a)
	All
property rights in any Documents recording, incorporating or referring to any of the information which a party is by this agreement required to keep confidential will be owned
throughout the world by the other party and are by this agreement assigned by the party to the other party with effect from the time of the creation of the Documents.

	(b)
	A
party must make sure that it enters into agreements with its officers, employees, professional advisers and auditors (and, in the case of the Licensee, the Public Good Licensees and
their officers, employees, professional advisers and auditors) which are consistent with, and give effect to, the assignment in clause 00.

	(c)
	On
termination of this agreement, each party must return and must cause its officers, employees, professional advisers and auditors (and, in the case of the Licensee, the Public Good
Licensees and their officers, employees, professional advisers and auditors) to return to the other party all copies of any information which the party is required by this agreement to keep
confidential and all copies of any Documents incorporating such information.

 

	13.3
	Exclusion from obligations of confidentiality

The
obligations of confidentiality imposed by this clause 0 do not apply in relation to any information: 

	(a)
	which
is or becomes generally publicly available other than as a result of any breach of an obligation of confidence by the party required to keep that information confidential or any
person to whom the party required to keep that information confidential has disclosed that information (which, in the case of the Licensee, is deemed for the purposes of this clause 0 to
include the Public Good Licensees);

	(b)
	which
the party required to keep that information confidential is required by law, the order of any court or the rules of the ASX to disclose, provided that the party must immediately
notify the other party of such a requirement and, at the written request and cost of the other party, reasonably co-operate with and assist the other party to avoid such a requirement or
restrict the extent of the disclosure; or

	(c)
	which
the other party consents (subject to such restrictions and conditions as the other party imposes in its absolute discretion) to the party required to keep that information
confidential using or disclosing.

 

	14.
	Notices

Any
communication under or in connection with this agreement: 

	(a)
	must
be in writing;

	(b)
	must
be sent to the party at the address of that party as stated in this agreement or such other address as is notified in writing from time to time by that party; 

14

 

	(c)
	must
be signed by the party making the communication (or on its behalf by the solicitor for, or by any attorney, director, secretary, or authorised agent of, that party);

	(d)
	must
be delivered or posted by prepaid post to the address of the addressee, in accordance with clause 00; and

	(e)
	will
be deemed to be received by the addressee:

	(i)
	(in
the case of prepaid post) on the third Business Day after the date of posting to an address within Australia;

	(ii)
	(in
the case of delivery by hand) on delivery at the address of the addressee as provided in clause 00, unless that delivery is made on a day which is not a Business Day or
after 5.00 pm on a Business Day, in which case that communication will be deemed to be received at 9.00 am on the next Business Day.

 

	15.
	Stamp Duty and costs

Except
as provided to the contrary in the Heads of Agreement: 

	(a)
	any
stamp duty payable in respect of this agreement will be payable by the Licensor; and

	(b)
	each
party will bear its own costs of and associated with negotiating and preparing this agreement.

 

	16.
	Amendment

This
agreement can only be amended by an instrument in writing signed by both parties. 

	17.
	Governing law

This
Deed is governed by the laws of the State of Western Australia, Australia. The parties irrevocably submit to the non-exclusive jurisdiction of the Courts of the State of Western
Australia and the Federal Court of Australia, including any Court which may hear appeals from those Courts. The parties must not object to the jurisdiction of such a Court on the basis that it is an
inconvenient forum. 

	18.
	General

	18.1
	Assignment

Neither
party can assign, novate or otherwise transfer any of its rights or obligations under this agreement without the prior written consent of the other party (which must not be unreasonably
withheld). 

	18.2
	Entire agreement

To
the extent permitted by law, in relation to the subject matter of this agreement, this agreement: 

	(a)
	embodies
the entire understanding of the parties and constitutes the entire terms agreed upon between the parties; and

	(b)
	supersedes
any prior agreement (whether or not in writing, including the Heads of Agreement) between the parties. 

For
the avoidance of doubt, this clause does not derogate from or limit the requirement that the condition precedent in clause 0 is satisfied before clauses 0 to 0 of this agreement become
binding on, grant any rights to or impose any obligations on either party. 

15

 
	18.3
	Waiver and variation

A
provision in or right created under this agreement may not be: 

	(a)
	waived
except in writing signed by the party granting the waiver; or

	(b)
	varied
except in writing signed by all the parties. 

A
waiver of a breach of this agreement does not constitute a waiver of any future breach of this agreement (including a future breach of the same provision of this agreement). 

	18.4
	Severability

If
any part or a provision of this agreement is judged invalid or unenforceable in a jurisdiction, it is severed for that jurisdiction and the remainder of this agreement will continue to operate. 

	18.5
	No representations or warranties

In
entering into this agreement the parties have not relied on any representations or warranties about its subject matter except as provided in this agreement. 

	18.6
	Relationship

Nothing
contained in this agreement should be construed as constituting a partnership, joint venture or fiduciary or agency relationship between the parties. 

16

 

Signed as an agreement. 

	

Signed by Professor Roger Dawkins on behalf of C Y O'Connor ERADE Village Foundation incorporating the Immunogenetics Research Foundation and the Institute of Molecular Genetics and Immunology Incorporated (ABN 67 161 830 965) in the presence
of:	
 	

 Signature
	

 Signature of Witness	
 	

 
	

 Name of Witness in full	
 	

 
	

Signed by Dr Mervyn Jacobson on behalf of Genetic Technologies Limited (ACN 009 212 328) in the presence of:	
 	

 Signature
	

 Signature of Witness	
 	

 
	

 Name of Witness in full	
 	

 

17

QuickLinks

Exhibit 4.12

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00089-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00089-of-00352.parquet"}]]