Document:

EXHIBIT
4.1

    

    NEITHER
THE ISSUANCE AND SALE OF THIS NOTE NOR THE SECURITIES INTO WHICH THIS NOTE IS
CONVERTIBLE HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED,
OR APPLICABLE STATE SECURITIES LAWS.  THE SECURITIES MAY NOT BE OFFERED FOR
SALE, SOLD, TRANSFERRED OR ASSIGNED IN THE ABSENCE OF (I) AN EFFECTIVE
REGISTRATION STATEMENT FOR THE SECURITIES UNDER THE SECURITIES ACT OF 1933, AS
AMENDED, OR (II) AN OPINION OF COUNSEL, IN A FORM REASONABLY ACCEPTABLE TO THE
COMPANY, THAT REGISTRATION IS NOT REQUIRED UNDER SAID ACT.  NOTWITHSTANDING
THE FOREGOING, THIS NOTE MAY BE PLEDGED IN CONNECTION WITH A BONA FIDE MARGIN
ACCOUNT OR OTHER LOAN OR FINANCING ARRANGEMENT SECURED BY THIS NOTE.  ANY
TRANSFEREE OF THIS NOTE SHOULD CAREFULLY REVIEW THE TERMS OF THIS NOTE.
 THE PRINCIPAL AMOUNT REPRESENTED BY THIS NOTE AND, ACCORDINGLY, THE
SECURITIES ISSUABLE UPON CONVERSION HEREOF MAY BE LESS THAN THE AMOUNTS SET
FORTH ON THE FACE HEREOF PURSUANT TO THIS NOTE.

    

    DESIGN
SOURCE, INC.

    8.25%
CONVERTIBLE PROMISSORY NOTE

    

    
      
        
          	
                  Issuance
      Date:  May 8, 2009

                	
                  Principal
      Amount: U.S. $80,000.00

                

        

      

    

    

    FOR VALUE
RECEIVED, Design Source,
Inc., a Nevada corporation (the "Company"), hereby promises to
pay to MILESTONE ENHANCED FUND
LTD. or registered assigns ("Holder") the amount set out
above as the Original Principal Amount (as reduced pursuant to the terms hereof
pursuant to redemption, conversion or otherwise, the "Principal") when due, whether
upon the Maturity Date (as defined below), acceleration, redemption or otherwise
(in each case in accordance with the terms hereof) and to pay interest at the
rate of 8.25% per annum  ("Interest") from the date set
out above as the Issuance Date (the "Issuance Date") until the same
becomes due and payable on the Maturity Date.

    

    1.           PAYMENTS OF PRINCIPAL;
MATURITY.  Payment of principal and interest due on this Note is
payable no later than November 8, 2010 (the “Maturity Date”); provided, however,
that each of the parties hereto may mutually agree to extend the term of this
Note beyond the Maturity Date.

    

    2.           PREPAYMENT.  The
Company and the Holder understand and agree that the principal amount of the
Note and any interest accrued thereon be prepaid by the Company at any time
without penalty.

    

    3.           CONVERSION OF NOTE.
 This Note shall be convertible into shares of the Company’s common stock
(the "Shares"), on the
terms and conditions set forth in this Section 3.

    
      
         

      

      
        1

        
          

        

      

      
         

      

    

    (a)           Conversion Right.
 Subject to the provisions of Section 3(c)(i) hereof and pursuant to terms
to be mutually agreed upon by the Company and the Holder in writing at a later
date, the Holder shall be entitled to convert any portion of the outstanding and
unpaid principal and interest balance due on the Note in accordance with Section
3 of this Note into Shares at a conversion price to be mutually determined by
the Company and the Holder (the “Conversion
Price”).   The Company shall not issue any fractions of a
Share upon any conversion.  If the issuance would result in the issuance of
a fraction of a Share, the Company shall round such fraction of a Share up to
the nearest whole Share.  The Company shall pay any and all taxes that may
be payable with respect to the issuance and delivery of Shares upon conversion
of any conversion amount.

    

    (b)           Mechanics of
Conversion.

    

    (i)          Notice of
Conversion. To convert this Note, the Holder hereof shall deliver
written notice thereof, substantially in the form of Exhibit A to
this Note, with appropriate insertions (the “Conversion Notice”),
to the Company at its address as set forth herein.  The date upon
which the conversion shall be effective (the “Conversion Date”)
shall be deemed to be the date set forth in the Conversion
Notice.  Except as otherwise provided herein, the Company shall not
have the right to object to the conversion or the calculation of the applicable
conversion price, absent manifest error.  Any conversion of any
portion of the Note to Shares shall be deemed to be a pre-payment of principal,
without any penalty, and shall be credited against any future payments of
principal in the order that such payments become due and payable

    

    (ii)          Disputes.  In
the event of a dispute as to the number of Shares issuable to the Holder in
connection with a conversion of this Note, the Company shall issue to the Holder
the number of Shares not in dispute and resolve such dispute using good faith
efforts with the Holder.

    

    (c)           Limitations on
Conversions. 

    

    Beneficial Ownership.
 The Holder of this Note (including any successor, transferee or assignee)
shall not have the right or obligation to convert any portion of this Note
pursuant to Section 3(b)(i) hereof to the extent that, after giving effect to
such conversion, the Holder (together with the Holder's Affiliates) would
beneficially own in excess of 4.99% (as may be adjusted in the manner described
below, the "Maximum
Percentage") of the number of shares of Common Stock outstanding
immediately after giving effect to such conversion.  For purposes of the
foregoing sentence, the number of shares of Common Stock beneficially owned by
the Holder and its Affiliates shall include the number of shares of Common Stock
issuable upon conversion of this Note with respect to which the determination of
such sentence is being made, but shall exclude the number of shares of Common
Stock which would be issuable upon (A) conversion of the remaining, nonconverted
portion of this Note beneficially owned by the Holder or any of its Affiliates
and (B) exercise or conversion of the unexercised or nonconverted portion of any
other securities of the Company (including, without limitation, any Other Notes
or Warrants) subject to a limitation on conversion or exercise analogous to the
limitation contained herein beneficially owned by the Holder or any of its
Affiliates.  Except as set forth in the preceding sentence, for purposes of
this Section 3(c), beneficial ownership shall be calculated in accordance with
Section 13(d) of the Securities Exchange Act of 1934, as amended.  For
purposes of this Section 3(c), in determining the number of outstanding shares
of Common Stock, the Holder may rely on the number of outstanding shares of
Common Stock as reflected in the most recently filed document among: (x) the
Company's most recent public filing with the Securities and Exchange Commission
containing such information, (y) a more recent public announcement by the
Company or (z) any other notice by the Company or the Transfer Agent setting
forth the number of shares of Common Stock outstanding.  For any reason at
any time, during regular business hours of the Company and upon the written
request of the Holder, the Company shall within two (2) Business Days confirm in
writing to the Holder the number of shares of Common Stock then outstanding.
 In any case, the number of outstanding shares of Common Stock shall be
determined after giving effect to the conversion or exercise of securities of
the Company, including this Note, by the Holder or its Affiliates since the date
as of which such number of outstanding shares of Common Stock was reported.
 By written notice to the Company, the Holder may increase or decrease the
Maximum Percentage to any other percentage specified in such notice; provided
that (i) any such increase will not be effective until the sixty-first (61st ) day
after such notice is delivered to the Company, (ii) any such increase or
decrease will apply only to the Holder and not to any other holder of Notes, and
(iii) such Maximum Percentage shall not, in any event, exceed
19.99%.

    
      
         

      

      
        2

        
          

        

      

      
         

      

    

    4.           EVENT OF
DEFAULT.  Failure by the Company to make payment pursuant to
Section 1 hereof shall constitute an event of default (“Event of
Default”).  In an Event of Default, the Holder shall be entitled to
all legal remedies available to it to pursue collections, and the Company shall
bear all reasonable costs of collection, including but not limited to necessary
attorneys’ fees.

    

    5.           NO
WAIVER.  No failure or delay by the Holder in exercising any
right, power or privilege under this Note shall operate as a waiver thereof nor
shall any single or partial exercise thereof preclude any other or further
exercise thereof or the exercise of any other right, power or
privilege.  The rights and remedies herein provided shall be
cumulative and not exclusively of any rights or remedies provided by applicable
law.  No course of dealing between the Company and the Holder shall
operate as a waiver of any rights by the Holder.

    

    6.           NOTICES;
PAYMENTS.

    

    (a)           Notices.
 Whenever notice is required to be given under this Note, unless otherwise
provided herein, such notice shall be given in accordance with the Securities
Purchase Agreement.  Unless a specific notice is otherwise required
under this Note, the Company shall provide the Holder with prompt written notice
of all actions taken pursuant to this Note, including in reasonable detail a
description of such action and the reason therefore.

    

    (b)           Payments.
 Except as otherwise provided in this Note, whenever any payment of cash is
to be made by the Company to the Holder, such payment shall be made in lawful
money of the United States of America by a check drawn on the account of the
Company and sent via overnight courier service to the Holder at such address as
previously provided to the Company in writing (which address shall be set forth
in the Securities Purchase Agreement); provided that the Holder may elect to
receive a payment of cash via wire transfer of immediately available funds by
providing the Company with prior written notice setting out such request and the
Holder's wire transfer instructions.  Whenever any amount expressed to be
due by the terms of this Note is due on any day which is not a Business Day, the
same shall instead be due on the next succeeding day which is a Business
Day.

    
      
         

      

      
        3

        
          

        

      

      
         

      

    

    7.           TRANSFER.  The
Holder acknowledges and agrees that this Note may only be offered, sold,
assigned or transferred by the Holder if consented to in writing by the
Company.

    

    8.           CONSTRUCTION;
HEADINGS.  This Note shall be deemed to be jointly drafted by the
Company and the Holder and shall not be construed against any person as the
drafter hereof. The headings of this Note are for convenience of reference and
shall not form part of, or affect the interpretation of, this Note.

    

    9.           SEVERABILITY.  In
the event that one or more of the provisions of this Note shall for any reasons
be held invalid, illegal, or unenforceable in any respect, such invalidity,
illegality or unenforceability shall not affect any other provision of this
Note, but this Note shall be construed as if such invalid, illegal or
unenforceable provision had never been contained herein.

    

    10.           GOVERNING
LAW.  This Note and the rights and obligations of the Company
and the Holder shall be governed by and construed in accordance with the laws of
the State of New York.

    

    [SIGNATURE
PAGE FOLLOWS]

    
      
         

      

      
        4

        
          

        

      

      
         

      

    

    IN
WITNESS WHEREOF, the Company has caused this Note to be duly executed as of the
Issuance Date set out above.

    

    
      
        
          
            
              
                	 
      	
                        DESIGN
      SOURCE, INC.

                      
	 	 
	 
      	By:	/s/
      Peter L. Coker
	 
      	
                        Name:

                      	
                        Peter
      Coker

                      
	 
      	
                        Title:

                      	
                        Secretary

                      

              

            

          

        

      

    

    
      
         

      

      
        5

        
          

        

      

      
         

      

    

     

    EXHIBIT
A

     

    NOTICE OF
CONVERSION

     

    (To
be executed by the Holder in order to convert the Note)

     

    
      	
              TO:

            	 
      

    

    

    The
undersigned hereby irrevocably elects to convert $______________________________
of the principal amount of the above Note into Shares of Common Stock of Design
Source, Inc., according to the conditions stated therein, as of the Conversion
Date written below.

    
      
        
          
            
              
                
                  
                    
                      
                        
                          
                            
                              
                                
                                  
                                    
                                      
                                        
                                          	
                                                  Conversion
      Date:

                                                	 	 
      
	
                                                  Applicable
      Conversion Price:

                                                	 	 
      
	
                                                  Signature:

                                                	 	 
      
	
                                                  Name:

                                                	 	 
      
	
                                                  Address:

                                                	 	 
      
	
                                                  Amount
      to be converted:

                                                	 	
                                                  $

                                                	 
      
	
                                                  Amount
      of Note unconverted:

                                                	 	
                                                  $

                                                	 
      
	
                                                  Conversion
      Price per Unit:

                                                	 	
                                                  $

                                                	 
      
	
                                                  Number
      of shares of Common Stock and Warrants to be issued including as payment
      of interest, if applicable:

                                                	 	 
      
	
                                                  Please
      issue the shares of Common Stock and Warrants in the following name and to
      the following address:

                                                	 	 
      
	
                                                  Issue
      to the following account of the Holder:

                                                	 	 
      
	
                                                  Authorized
      Signature:

                                                	 	 
      
	
                                                  Name:

                                                	 	 
      
	
                                                  Title:

                                                	 	 
      
	
                                                  Phone
      Number:

                                                	 	 
      
	
                                                  Broker
      DTC Participant Code:

                                                	 	 
      
	
                                                  Account
      Number:

                                                	 	 
      

                                        

                                      

                                    

                                  

                                

                              

                            

                          

                        

                      

                    

                  

                

              

            

          

        

      

    

    
      
         

      

      
        6Exhibit 10.111
    

    

    

    
      SECURED NOTE
    

    
    	
          
            $3,000,000
          

        	
           
        	
          June 15, 2009
        

    

    
      FOR VALUE RECEIVED,  Ocimum Biosolutions Inc., a Delaware
      corporation, (the “Ocimum”) and Ocimum Biosolutions India Limited, a
      company incorporated under the Company Act, 1956, in the Republic of
      India (“Ocimum India”, and collectively with Ocimum, “Maker”), jointly
      and severally, promise to pay to Ore Pharmaceuticals Inc., a Delaware
      corporation (“Ore”), the principal sum of THREE MILLION Dollars
      ($3,000,000), as such amount may be adjusted in accordance with terms
      herein, (the “Principal Amount”) pursuant to the terms and conditions of
      that certain Security Agreement of even date herewith between Ore and
      Ocimum (the “Security Agreement”), together with interest thereon, if
      any, computed hereunder and any and all other sums which may be due and
      owing to the Ore in accordance with the terms contained herein and in
      the Security Agreement.  Ore and Maker may hereinafter be collectively
      referred to as the “Parties”.
    

    
      1.        Cancellation of
      Prior Promissory Note.  The Parties agree and acknowledge that
      upon execution of this Note and the Security Agreement, the Promissory
      Note dated December 14, 2007 (“Prior Note”) between
      the Maker and Ore (then doing business as Gene Logic Inc.) shall be
      deemed hereby cancelled, revoked, and superseded by this Secured Note
      (the “Note”).
    

    
      2.        Incorporation of
      Security and Security Agreement.  This Note is the “Note”
      referred to in the Security Agreement.  This Note is secured by the
      Collateral (as defined in the Security Agreement), which Collateral
      generally includes all accounts, equipment, inventory, documents,
      instruments, securities, deposit accounts and other assets of Ocimum now
      existing or hereafter acquired, and all proceeds of any of the
      foregoing.  Reference is made to the Security Agreement, which is
      incorporated by reference in its entirety into this Note, for terms and
      conditions applicable to this Note, including, without limitation,
      rights and obligations of payment and repayment hereof, events of
      default, and Ore’s rights and remedies upon the occurrence of any such
      events of default.
    

    
      3.        Maturity.  The
      Principal Amount shall be due and payable as described in Section 4.
      Interest shall accrue on the unpaid Principal Amount, subject to any
      adjustment provided in Section 4, at a rate of fifteen percent (15%) per
      annum, compounded monthly.  Interest hereunder shall be calculated on
      the basis of a three hundred sixty (360) days-per-year factor applied to
      the actual days on which there exists an unpaid balance under the Note.
    

    
      4.        Principal
      Adjustment and Payment Schedule.  The Principal Amount shall
      adjust as follows:
    

    	
        On July 15, 2009, the Principal Amount shall be increased by four
        percent (4%) of the then unpaid Principal Amount;
      
	
        On August 15, 2009, the Principal Amount shall be increased by five
        percent (5%) of the then unpaid Principal Amount; and
      
	
        On September 15, 2009, the Principal Amount shall be increased by
        eight percent (8%) of the then unpaid Principal Amount.
      

    
      Maker shall pay Ore according to the following schedule:
    

    	
        No less than fifty percent (50%) of the Principal Amount, adjusted to
        reflect interest described in Section 3 that has accrued since June
        15, 2009 and any adjustment to the Principal Amount as described in
        this Section 4 above that may have occurred, shall be due and payable
        to Ore on or prior to August 1, 2009;
      
	
        The remaining Principal Amount, if any, adjusted to reflect interest
        described in Section 3 that has accrued since June 15, 2009 and any
        adjustment to the Principal Amount as described in this Section 4
        above that may have occurred, shall be due and payable to Ore on or
        before September 15, 2009.
      

    
      
        

        

      

      
        

        

        
          

        

      

      
        

        

      

    

    
      Maker’s failure to make either payment in full and when due shall be
      deemed an Event of Default under Section 7 of the Security Agreement.
    

    
      5.        Waiver of
      Presentment, Etc.  Maker, for itself and its successors and
      assigns, hereby waives presentment and demand for payment, notice of
      intent to accelerate maturity, notice of acceleration of maturity,
      protest or notice of protest and nonpayment of this Note.  From time to
      time, without affecting the obligation of Maker to pay the
      then-outstanding Principal Amount of this Note, Ore may, at the option
      of Ore, extend the time for payment of principal hereof, reduce the
      payments hereunder, release anyone liable on this Note, accept a renewal
      of this Note, join in any extension or subordination, or exercise any
      option or election hereunder.  No one or more of such actions shall
      constitute a novation.
    

    
      6.       Costs of Collection.  Maker
      hereby agrees to pay all costs and expenses (including court costs and
      reasonable attorneys’ fees, whether or not litigation is commenced)
      incurred by Ore in collecting or attempting to collect or enforce its
      rights under this Note.
    

    
      7.        Rights and
      Remedies Cumulative.  Each right, power and remedy of Ore
      specified herein or available at law or in equity or by statute shall be
      cumulative and concurrent and shall be in addition to every other right,
      power or remedy provided for in this Note or available at law or in
      equity and the exercise or beginning of the exercise by Ore of any one
      or more of such rights, powers or remedies shall not preclude the
      simultaneous or later exercise by Ore of any or all other rights, powers
      or remedies.
    

    
      8.        Confession of
      Judgment.  Upon any default hereunder and to the extent
      permitted by law, Maker, for itself and its successors and assigns,
      authorizes any attorney admitted to practice before any court of record
      in the United States on behalf of Maker to confess judgment against
      Maker in the full amount due under this Note, including then-outstanding
      principal, accrued and unpaid interest and all other sums due
      hereunder.  Maker waives the benefit of any and every statute, ordinance
      or rule of court which may be lawfully waived conferring upon Maker any
      right or privilege, stay of execution, or supplementary proceeding or
      other relief from the immediate enforcement of a judgment or related
      proceedings on a judgment.  The authority granted herein shall not be
      exhausted by any one or more exercises or be extinguished by any
      judgment entered and may be exercised on one or more occasions and in
      one or more jurisdictions.  
    

    
      9.        Governing Law;
      Dispute Resolution; Notices; Jury Trial Waiver.  This Agreement
      shall be governed by and construed and enforced in accordance with the
      laws of the State of Maryland and the federal laws of the United States
      of America, without regard to principles of conflicts of laws.  The
      state or federal courts located within the State of Maryland shall have
      jurisdiction over any and all disputes arising from or related to this
      Agreement or the transactions contemplated hereby.  All proceedings
      between the Parties under or relating to this Agreement or any breach
      hereof shall be conducted solely in the English language. The Parties
      also consent to the service of process in connection with any dispute or
      claim arising hereunder by personal delivery, mailing such notice to the
      other party by registered or certified mail, postage prepaid at the
      addresses provided in the preamble of this Agreement or such other
      address as a Party may from time to time give notice of to the other
      Parties, or any other manner permitted by law.  EACH OF THE PARTIES
      HEREBY IRREVOCABLY WAIVES ALL RIGHT TO A TRIAL BY JURY IN ANY ACTION OR
      PROCEEDING ARISING OUT OF OR RELATING TO THIS AGREEMENT OR THE
      TRANSACTIONS CONTEMPLATED HEREBY.
    

    
      10.       No Assignment.
      Ocimum may not assign this Note, or its rights hereunder except in
      the case of a sale of substantially all of the assets of the Company.
    

    
      
        

        

      

      
        

        

        
          

        

      

      
        

        

      

    

    

    

    
      * * *
    

    
      IN WITNESS WHEREOF, Ocimum has caused this Note to be executed as an
      instrument under seal on its behalf by its duly authorized officer as of
      the day and year first above written.
    

    

    

    
    	
          
            OCIMUM BIOSOLUTIONS INC.:
          

        
	
           
        
	
           
        
	
          By:
        	
          /s/ Subash Lingareddy
        
	
          Name:
        	
          Subash Lingareddy
        
	
          Title:
        	
          Director
        

    

    
    	
          OCIMUM BIOSOLUTIONS INDIA LIMITED:
        	

        
	

        	
           
        
	

        	
           
        
	
          By:
        	
          /s/ Anuradha Acharya
        	
          (SEAL)
        
	
          Name:
        	
          Anuradha Acharya
        	

        
	
          Title:
        	
          CEO

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00160-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00160-of-00352.parquet"}]]