Document:

Termination Agreement and Mutual Release, dated as of June 7, 2005

 EXHIBIT 10.1 
  
 *** Portions of this Exhibit 10.1 have been omitted pending confidential treatment request by the Company. 
  
 TERMINATION AGREEMENT AND MUTUAL RELEASE 
  
 THIS TERMINATION AGREEMENT AND MUTUAL RELEASE (this “Agreement”) is
made and entered into effective as of July 8, 2005 (the “Effective Date”) by and between Optical Sensors Incorporated, dba väsamed, a Delaware corporation with its principal offices located at 7615 Golden Triangle Drive, Suite
C, Minneapolis, Minnesota 55344 (“OSI”), and Nellcor Puritan Bennett Incorporated, a Delaware corporation and a business unit of Tyco Healthcare Group L.P. with its principal offices located at 4280 Hacienda Drive, Pleasanton,
California 94588 (“NPB”) (each, a “Party” and collectively, the “Parties”). 
  
 RECITALS 
  
 WHEREAS, OSI entered into that certain Patent License Agreement, dated July 20, 1998, by which the Institute of Critical Care Medicine (“ICCM”) granted to OSI an exclusive license under certain patents issued to ICCM and patents
that issued on ICCM patent applications (the “ICCM License Agreement”); 
  
 WHEREAS, OSI developed a monitoring device (“Instrument”) and disposable fiber optic sensors to measure sublingual carbon dioxide (“Sensors”) pursuant to the license granted by the ICCM License
Agreement; 
  
 WHEREAS, OSI and NPB entered into that certain
Development and License Agreement, dated September 28, 2001, by which OSI granted to NPB an exclusive sublicense under the ICCM License Agreement, and an exclusive license under certain patents issued to OSI (the “Sublicense Agreement”);

  
 WHEREAS, OSI and NPB entered into that certain Exclusive
Supply Agreement, dated September 28, 2001, by which OSI agreed to manufacture and sell for a limited period of time private labeled Instruments and Sensors to NPB for distribution by NPB (the “Supply Agreement”); 
  
 WHEREAS, in connection with entering into the Sublicense Agreement and the
Supply Agreement, NPB and ICCM entered into that certain Supplemental Agreement, dated September 28, 2001, providing for certain arrangements between NPB and ICCM relating to the Sublicense Agreement (the “Supplemental Agreement”);

  
 WHEREAS, OSI is not a party to the Supplemental Agreement, and
neither NPB nor OSI contend that OSI assumed any obligations to ICCM under the Supplemental Agreement; 
  
 WHEREAS, OSI sold and transferred to NPB certain tooling and other equipment for the manufacture and testing of the Instruments and the Sensors in
connection with the prior termination of the Supply Agreement (collectively, the “Tooling”); 

 WHEREAS, NPB commenced manufacturing of Sensors at NPB’s facilities in or about February 2004;

  
 WHEREAS, NPB initiated a voluntary recall of Sensors in August
2004 following hospital reports of infections and the finding of Burkholderia cepacia, a pathogenic bacteria, in the buffered saline solution in which the Sensors were packaged (the “Sensor Recall”); 
  
 WHEREAS, NPB ceased manufacture, marketing and distribution of Sensors and
Instruments upon the Sensor Recall, and NPB has not resumed such manufacture, marketing and distribution; 
  
 WHEREAS, ICCM notified OSI by correspondence, dated December 6, 2004, of an alleged material breach of the ICCM License Agreement by failing, among other
things, to cause Instruments and Sensors to be developed and marketed in a commercially reasonable manner, and ICCM notified OSI by correspondence, dated April 4, 2005, that ICCM terminated the ICCM License Agreement (the “Purported ICCM
Termination”); 
  
 WHEREAS, OSI commenced an arbitration
before the American Arbitration Association and captioned Optical Sensors, Inc. v. Institute of Critical Care Medicine, Matter No. 51 133 Y 00603 05 relating to the ICCM License Agreement and the Purported ICCM Termination (the “ICCM
Arbitration”); 
  
 WHEREAS, OSI and ICCM have settled all
claims asserted in the ICCM Arbitration, ICCM has withdrawn the Purported ICCM Termination and agreed to terminate the Supplemental Agreement, and OSI and ICCM have agreed to dismiss the ICCM Arbitration with prejudice; and 
  
 WHEREAS, OSI and NPB desire to terminate the Sublicense Agreement and confirm
the prior termination of the Supply Agreement, and to provide for indemnification and releases arising out of any dealings between the Parties prior to the Effective Date or otherwise related to the design, manufacture and distribution of the
Instruments and Sensors, as set forth herein. 
  
 NOW, THEREFORE,
in consideration of the mutual promises set forth herein, the parties agree as follows: 
  
 AGREEMENT 
  
 1.
Termination of Sublicense Agreement and Supply Agreement. OSI and NPB agree that the Sublicense Agreement is terminated as of the Effective Date, the Supply Agreement was previously terminated in November 2003, and neither Party shall have
any rights or obligations of any kind or nature under the Sublicense Agreement or the Supply Agreement. Notwithstanding the foregoing or Section 8(c)(3) of the Sublicense Agreement, no section or provision of the Sublicense Agreement shall survive
termination of the Sublicense Agreement, except for Section 12 of the Sublicense Agreement. 
  

 2 

 2. Consideration for Termination and Mutual Release. 
  
 2.1. Tooling and Instruments. 
  
 (a) Transfer to OSI. NPB hereby transfers to OSI all right, title
and interest in and to: (a) the items of Tooling identified on Exhibit A attached hereto, and (b) thirty-six (36) Instruments previously manufactured by or for NPB and that have not been previously used for any purpose. OSI acknowledges and
agrees that it shall use such Instruments for OSI’s internal research and development purposes and IRB-approved clinical research only, and not for any patient management purpose, and that any transfer of such Instruments by OSI shall be
subject to the foregoing restrictions. 
  
 (b) Shipping.
Upon execution and delivery of this Agreement by OSI, NPB shall cause the items of Tooling identified on Exhibit A and thirty-six (36) Instruments to be shipped to OSI at its principal offices or other location in the domestic United States
designated by OSI in writing. Such Tooling and Instruments shall be packaged and crated under the supervision of an OSI employee, and NPB will reimburse OSI for its reasonable out-of-pocket travel and lodging expenses for one (1) OSI employee to
travel to NPB’s facility in Tijuana, Mexico for such supervision, subject to a maximum sum of $2,000. Such Tooling and Instruments shall be shipped via Federal Express Ground, freight and insurance prepaid by NPB. 
  
 (c) Representations and Warranties. NPB represents and warrants that
it owns such Tooling and Instruments free and clear of any encumbrances or liens and that, to NPB’s knowledge, all such Tooling and Instruments are in good working order, subject to normal wear and tear. Except as provided in this Section 2.1,
NPB makes no representations or warranties concerning the Tooling or Instruments transferred to OSI hereunder. 
  
 2.2. FDA Communications. NPB represents and warrants that as of the Effective Date it has delivered to OSI copies of all written communications
between NPB and the United States Food and Drug Administration (“FDA”) in connection with the Sensor Recall. 
  
 2.3. Communication with NPB Customers; Return of Instruments. NPB shall send correspondence, in a form reasonably agreed upon by NPB and OSI, to
all customers that purchased Instruments and/or Sensors from NPB. NPB shall accept the return of all Instruments transferred to third parties for value, and NPB and shall issue to such third parties a credit equal to all sums paid for such
Instruments that may be applied against the purchase of other Nellcor® products. NPB shall
permanently quarantine or destroy all such returned Instruments and certify such permanent quarantine or destruction to OSI and advise OSI of the names of any customers or third parties who have failed to return Instruments and Sensors to NPB.

  
 2.4. Clinical Investigation Information. NPB will
deliver to OSI, within ten (10) days of the Effective Date, copies of all documents received by NPB from clinical sites and investigators concerning clinical evaluations, outcome studies, and investigations related to the Instruments and Sensors
conducted prior to the Sensor Recall. 
  

 3 

 2.5. Customer Information. NPB will deliver to OSI contact information for all customers that
purchased Instruments and/or Sensors from NPB, which information OSI shall not transfer to any third party or use for any purpose other than to communicate with such NPB customers concerning any reintroduction of the Instruments and Sensors by OSI
or development of related devices covered by the ICCM License Agreement. 
  
 2.6. *** 
  
 2.7.
Cooperation. In order to aid OSI’s defense of any future allegation, action, suit, or demand asserted by ICCM, which relates to the Sublicense Agreement or NPB’s performance thereunder, NPB will, on request of OSI: (a) provide
non-privileged, relevant documents in NPB’s possession or control; (b) make NPB’s current employees available for interview by OSI and its attorneys, (c) produce NPB’s current employees at depositions and at any hearing, trial or
proceeding, at NPB’s expense; and (d) seek availability of former NPB employees for interview by OSI and its attorneys. 
  
 2.8. OSI Common Stock. Promptly following execution and delivery of this Agreement by NPB, OSI shall issue 175,000 shares of OSI’s common
stock to NPB. OSI represents and warrants that: 
  
 (a)
Capitalization. The authorized capital of OSI consists of: 
  
 (i) Preferred Stock. 5,000,000 shares of Preferred Stock are authorized, of which 4,333,334 shares have been designated Series A Preferred Stock and 4,333,334 shares are issued and outstanding; 236,934 shares have been designated
Series B Preferred Stock and 236,934 shares are issued and outstanding; 115,000 shares have been designated Series C Preferred Stock and 78,354 shares are issued and outstanding; and 250,000 shares have been designated Series A Junior Preferred
Stock and no shares are issued and outstanding. 
  
 (ii)
Common Stock. 30,000,000 shares of common stock are authorized, of which 3,633,289 are issued and outstanding, excluding the shares being issued to NPB hereunder. 
  
 (b) Valid Issuance of Common Stock. The OSI common stock that is being issued to NPB hereunder, when issued and
delivered, will be duly and validly issued, fully paid, and nonassessable. 
  
 (c) Authorization. All corporate action on the part of OSI, its officers, directors and shareholders necessary for the authorization, execution and delivery of this Agreement, and the authorization, issuance,
and delivery of the common stock being issued hereunder has been taken prior to OSI’s execution of this Agreement. 
  

	***	Portions of this Exhibit 10.1 have been omitted pending confidential treatment request by the Company. 

  

 4 

 (d) Governmental Consents. Assuming the accuracy of NPB’s representations and warranties in
Section 2.9, no consent, approval, order or authorization of, or registration, qualification, designation, declaration or filing with, any federal, state or local governmental authority on the part of OSI is required in connection with the issuance
of the OSI common stock hereunder. 
  
 (e) Restrictive
Legend. Upon request of NPB, OSI shall cause any restrictive legend to be removed from the stock certificate delivered to NPB pursuant to this Agreement, or issue to NPB a new certificate therefor free of any restrictive legend, if, with such
request, OSI shall have received an opinion of counsel to the effect that any transfer by the holder of the securities evidenced by such certificate will not violate the Securities Act of 1933, as amended (the “Securities Act”) and
applicable state securities laws, unless any such restrictive legend may be removed pursuant to Rule 144(k) of the Securities Act or any successor rule, in which case no such opinion letter shall be required. 
  
 2.9. NPB Representations and Warranties. NPB represents and warrants
that: 
  
 (a) Authorization. All corporate action on the
part of NPB, its officers, directors and shareholders necessary for the authorization, execution and delivery of this Agreement has been taken prior to NPB’s execution of this Agreement. 
  
 (b) Investment. The common stock being acquired hereunder is being
acquired for investment for NPB’s own account and not with the view to, or for resale in connection with, any distribution or public offering thereof. NPB understands that the common stock being acquired hereunder has not been registered under
the Securities Act, or any state securities laws by reason of their contemplated issuance in transactions exempt from the registration requirements of the Securities Act and applicable state securities laws and that the reliance of OSI and others
upon these exemptions is predicated in part upon this representation by NPB. NPB further understands that common stock being acquired hereunder may not be transferred or resold without registration under the Securities Act and any applicable state
securities laws, or pursuant to an exemption from the requirements of the Securities Act and applicable state securities laws. NPB qualifies as an “accredited investor,” as defined in Rule 501 of Regulation D under the Securities Act. NPB
acknowledges that OSI has made available to NPB via EDGAR OSI’s Annual Report on Form 10-KSB for the year ended December 31, 2004 and all other reports, registrations statements and filings made by OSI with the Securities and Exchange
Commission since January 1, 2005. NPB acknowledges that OSI has made available to NPB at a reasonable time prior to the execution of this Agreement the opportunity to ask questions and receive answers concerning the business, operations and
financial condition of OSI and the terms and conditions of the issuance of securities contemplated by this Agreement and to obtain any additional information requested by NPB. NPB is able to bear the loss of its entire investment in the common stock
being acquired hereunder and has such knowledge and experience of financial and business matters that it is capable of evaluating the merits and risks of the investment to be made pursuant to this Agreement. 
  

 5 

 3. Mutual Release. Except for (a) *** indemnity obligations for third party claims set forth in
Section 2.6, and (b) breaches of this Agreement, OSI and NPB, on behalf of the themselves and their respective officers, directors, employees, agents, representatives, shareholders, affiliates, divisions, parent entities, subsidiaries, predecessors
in interest, successors in interest, and assigns hereby fully and forever release and discharge the other Party and that Party’s respective officers, directors, employees, agents, representatives, shareholders, affiliates, divisions, parent
entities, subsidiaries, predecessors in interest, successors in interest, and assigns from, and agree not to sue concerning, any claim, duty, obligation, cause of action, liability, damage, loss, judgment, and issues of any kind or nature
whatsoever, whether presently known or unknown, suspected or unsuspected, contingent or absolute, disclosed or undisclosed, that any of them may now, or in the future, possess arising from, or in any way related to: (i) the Sublicense Agreement,
(ii) the Supply Agreement, (iii) the design, manufacture, marketing, and distribution of the Instruments and the Sensors; (iv) the Sensor Recall, (v) the Purported ICCM Termination, (vi) the ICCM Arbitration, (vii) the withdrawal of the Instruments
and Sensors from the market, (viii) and any other acts or omissions of the other Party prior to the Effective Date of this Agreement. 
  
 4. Release of Unknown Claims. The release provided by this Agreement extends to claims each releasing Party does not know or suspect to exist at
the time of the release, which if known, might have affected the releasing Party’s decision regarding the release contained herein. Each Party shall be deemed to waive and relinquish, to the full extent permitted by law, any and all provisions,
rights and benefits conferred by any law of any state or territory of the United States, or principle of common law, which governs or limits a person’s release of unknown claims, including, but not limited to Section 1542 of the California
Civil Code. Each Party acknowledges that it may discover facts in addition to or different from those that it now knows or believes to be true with respect to the subject matter of the release, but that it is such Party’s intention to fully,
finally and forever settle and release any and all claims released hereby known or unknown, suspected or unsuspected, which now exist, or heretofore existed, or may hereafter exist, and without regard to the subsequent discovery or existence of such
additional or different facts. 
  
 5. Non-Disparagement and
Non-Disruption. OSI and NPB agree to refrain from any disparagement, defamation, libel, slander, disruption or any other actions adverse to the interests of the other Party and that Party’s officers, directors, employees, agents,
shareholders, affiliates, divisions, parent entities, subsidiaries, predecessors in interest, successors in interest, and assigns. 
  
 6. No Admission of Liability. The Parties acknowledge and agree that nothing contained in this Agreement, including without limitation the
exceptions to the mutual release set forth in Section 3, shall be deemed or construed to be an admission by either Party of any fault or liability whatsoever to the other Party or to any third party. Each Party denies any and all fault, wrongdoing,
and liability of any kind in connection with the transactions and occurrences described herein. 
  

	***	Portions of this Exhibit 10.1 have been omitted pending confidential treatment request by the Company. 

  

 6 

 7. Additional Representations and Warranties. OSI and NPB each represent and warrant that:

  
 7.1. Advice of Legal Counsel. Each Party has been
represented by legal counsel of its choice in the preparation, negotiation, and execution of this Agreement. 
  
 7.2 No Pending or Future Actions. Each Party represents and warrants that it is not a party to, and it does not intend to commence, any action or
proceeding against the other Party or any other person or entity released under Section 3. 
  
 7.3 No Other Representations. Neither Party (nor any of that Party’s officers, directors, employees, agents, representatives, shareholders, affiliates, divisions, parent entities, subsidiaries,
predecessors in interest, or successors in interest) has made any statement, representation, or promise regarding any matter relied upon by the other Party in entering into this Agreement, except as expressly stated in this Agreement. 
  
 7.4 No Assignment of Matters Released. Each Party represents and
warrants that it has not assigned, transferred, or granted to any third party any of the claims, causes of action or other matters released under this Agreement. 
  
 7.5 Authority. The person executing this Agreement on behalf of each Party is duly authorized to bind that Party to
all of the terms and conditions hereof. 
  
 8.
Confidentiality. Each Party agrees that the existence of this Agreement and all of the terms hereof are confidential, and that each Party shall not disclose, or permit the disclosure of, this Agreement or any of its terms to any third party,
except to each Party’s officers, directors, employees, and advisors with a need to know the terms hereof; provided, however, that OSI shall be permitted to disclose and file this Agreement in connection with its reporting obligations under the
Securities Exchange Act of 1934, in which event OSI shall request confidential treatment of specific provisions of this Agreement mutually agreed to by OSI and NPB consistent with the position of Securities Exchange Commission with respect to
confidential treatment requests. In the event either Party is required by other law or valid order of a court or other governmental authority to disclose this Agreement, the disclosing Party shall notify the other Party in writing in advance of such
disclosure in order to afford the other Party an opportunity to seek a protective order or other relief from disclosure of this Agreement, or to obtain confidential treatment by the party to whom it is disclosed. 
  
 9. Attorney’s Fees and Costs. Each Party shall bear its own
attorney’s fees and costs incurred in connection with the preparation and negotiation of this Agreement. 
  
 10. Assignment. Neither Party may assign this Agreement, without the prior written consent of the other Party. Subject to the foregoing, this
Agreement shall bind and inure to the benefit of the respective parties hereto and their permitted successors and assigns. 
  
 11. Governing Law. This Agreement shall for all purposes be governed exclusively by Delaware law, excluding choice of law principles. 

 

 7 

 12. Entire Agreement; Amendment. This Agreement, including the exhibits hereto, constitutes the
full and entire understanding and agreement between the Parties with regard to the subject matter hereof, and this Agreement replaces and supersedes any prior oral or written communications between the parties with respect to such subject matter.
Neither this Agreement nor any term hereof may be amended, modified, waived, discharged or terminated other than by a written instrument signed by the Parties hereto. 
  
 13. Titles and Subtitles. The titles and subtitles used in this Agreement are used for convenience only and are not
to be considered in construing or interpreting this Agreement. 
  
 14. Severability. If any provision of this Agreement is held to be unenforceable under applicable law by any court of competent jurisdiction, such provision shall be excluded from this Agreement and the balance of the Agreement shall
be interpreted as if such provision were so excluded and shall be enforceable in accordance with its terms. 
  
 15. Counterparts. This Agreement may be executed in counterparts, each of which shall be deemed an original, but all of which together shall
constitute one and the same instrument. Facsimile execution and delivery of this Agreement shall be legal, valid and binding execution and delivery for all purposes. 
  
 IN WITNESS WHEREOF, the parties have caused this Agreement to be executed and delivered as of the Effective Date.

  

			
	NELLCOR PURITAN BENNETT	 	OPTICAL SENSORS INCORPORATED
	INCORPORATED	 	dba VÄSAMED
		
	 /s/ David Sell

	 	 /s/ Paulita LaPlante

	Signature	 	Signature
		
	David Sell	 	Paulita LaPlante
	Print Name	 	Print Name
		
	President, Nellcor	 	President & CEO
	Print Title	 	Print Title

  

 8 

 EXHIBIT A 
  
 Tooling and Equipment to Be Transferred to OSI 
  

							
	 Description

	  	NPB

	  	OSI

	  	QTY

	 	  	Asset#	  	Asset#	  	 
	 Cutter
	  	MO113627	  	101084	  	1
	 Stripper
	  	MO113626	  	101085	  	1
	 Cleaver - backup
	  	MO113656	  	101083	  	1
	 Interferometer / camera and monitor
	  	 	  	100461	  	1
	 UV Cure System
	  	 	  	100684	  	1
	 	  	 	  	101035,	  	 
	 UV Calibration Meter & Detector
	  	 	  	101037	  	1
	 Optrode Placement (Includes camera/monitor/5-wheels)
	  	MO113631	  	101095	  	1
	 	  	 	  	100632,	  	 
	 	  	 	  	100321	  	 
	 Tubing Cutter
	  	MO113636	  	101124	  	1
	 Extra Wheels - 5 spares
	  	 	  	 	  	5
	 	  	 	  	100377,	  	 
	 Microscope / Lamp
	  	 	  	100176	  	1
	 Optrode Cap Manufacturing Station
	  	 	  	101125	  	1
	 Package Purge
	  	MO113632	  	101099	  	1
	 Sparger / Calibrant
	  	 	  	 	  	1
	 Cap Assembly
	  	 	  	101100	  	1
	 Torque wrench
	  	 	  	101098	  	1

  
 Any tooling rights for disposable
CapnoProbe component manufacture which reside at Nellcor suppliers (Dynaplast, ETI, Girard Rubber, Linhardt, Europac, Trumed, and Illbrook) 
  

 9Eighth Amendment to Lease Agreement dated June 30, 2005

 EXHIBIT 10.2 
  
 EIGHTH AMENDMENT TO LEASE AGREEMENT 
  
 THIS EIGHTH AMENDMENT TO LEASE AGREEMENT (the “Eighth Amendment”) is made and entered into this 30th day of June 2005, by and between FIRST INDUSTRIAL, L.P. a Delaware Limited Partnership (“Landlord”), and
OPTICAL SENSORS INCORPORATED, d/b/a Vasamed, a Delaware corporation (“Tenant”). 
  
 WITNESSETH: 
  
 WHEREAS, Landlord and Tenant have heretofore entered into a certain Standard Commercial Lease dated October 7, 1991 (the “Original Lease”) pursuant to which Landlord leased to Tenant and Tenant leased from Landlord
certain premises commonly known as 7615 Golden Triangle Drive, Suite A, Eden Prairie, Minnesota (the “Premises”); and 
  
 WHEREAS, Landlord and Tenant entered into a certain First Amendment to Lease Agreement dated April 26, 1996 (the “First Amendment”; the Original
Lease and the First Amendment are hereinafter collectively referred to as the “Lease”); and 
  
 WHEREAS, Landlord and Tenant entered into a certain Second Amendment to Lease Agreement dated April 14, 1997 (the “Second Amendment”; the Original Lease, First Amendment and Second Amendment
are hereinafter collectively referred to as the “Lease”); and 
  
 WHEREAS, Landlord and Tenant entered into a certain Third Amendment to Lease Agreement dated September 3, 1999 (the “Third Amendment”; the Original Lease, First Amendment, Second Amendment and Third Amendment are
hereinafter collectively referred to as the “Lease”); 
  
 WHEREAS, Landlord and Tenant entered into a certain Fourth Amendment to Lease Agreement dated June 1, 2000 (the “Fourth Amendment”; the Original Lease, First Amendment, Second Amendment, Third Amendment and Fourth
Amendment are hereinafter collectively referred to as the “Lease”); 
  
 WHEREAS, Landlord and Tenant entered into a certain Fifth Amendment to Lease Agreement dated March 28, 2001 (the “Fifth Amendment”; the Original Lease, First Amendment, Second Amendment, Third Amendment, Fourth
Amendment and Fifth Amendment are hereinafter collectively referred to as the “Lease”); 
  
 WHEREAS, Landlord and Tenant entered into a certain Sixth Amendment to Lease Agreement dated January 7, 2002 (the “Sixth Amendment”; the Original Lease, First Amendment, Second Amendment, Third
Amendment, Fourth Amendment, Fifth Amendment and Sixth Amendment are hereinafter collectively referred to as the “Lease”); 
  
 WHEREAS, Landlord and Tenant entered into a certain Seventh Amendment to Lease Agreement dated October 30, 2003 (the “Seventh Amendment”; the
Original Lease, First Amendment, Second Amendment, Third Amendment, Fourth Amendment, Fifth Amendment, Sixth Amendment and Seventh Amendment are hereinafter collectively referred to as the “Lease”); 
  

 1 

 NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged,
the parties hereto hereby agree as follows: 
  

	1.	Recitals. The foregoing recitals are hereby incorporated as if fully rewritten and restated in the body of this Eighth Amendment. All initially capitalized terms used
but not defined herein shall have the meanings ascribed to such terms in the Lease. 

  

	2.	Term. The term of the Lease shall expire on March 31, 2008. 

  

	3.	Premises. Effective June 27, 2005, the premises shall be expanded to total 23,687 square feet; (13,434 square feet office, 8,205 square feet lab, 2,228 square feet
warehouse) located in Suite A, 7615 Golden Triangle Drive, as further depicted on attached Exhibit A. 

  

	4.	Tenant’s Proportionate Share. Effective July 1, 2005 Tenant’s Proportionate Share of Operating Expenses shall be 18.95%. 

  

	5.	Base Rent. Effective June 27, 2005, the Base Rent for the Premises shall be payable by Tenant, in advance, in monthly installments, in the indicated amount:

  

							
	 Lease Period

	  	Annual Base Rent

	  	Monthly Base Rent

	 June 27, 2005 - September 30, 2005
	  	$	0.00	  	$	0.00
	 October 1, 2005 - March 31, 2006
	  	$	190,427.64	  	$	15,868.91
	 April 1, 2006 - March 31, 2008
	  	$	196,171.44	  	$	16,347.62

  

	6.	Condition of Space. Tenant agrees that Tenant is familiar with the condition of the Premises and the Property, and Tenant hereby accepts the foregoing on an
“AS-IS,” “WHERE-IS” basis, except that Landlord agrees to steam clean the carpeted area of the expansion space. Tenant understands and acknowledges that carpets are not new and cleaning them may only result in a marginal
improvement in appearance. Tenant acknowledges that neither Landlord nor Agent nor any representative of Landlord has made any representation as to the condition of the foregoing or that suitability of the foregoing for Tenant’s intended use.
Tenant represents and warrants that Tenant has made its own inspection of the foregoing, Neither Landlord nor Agent shall be obligated to make any repairs, replacements or improvements (whether structural or otherwise) of any kind or nature in
connection with, or in consideration of this Lease. 

  

	7.	Tenant Improvement Allowance. Landlord shall provide a tenant improvement allowance of Twenty Five Thousand Dollars and 00/100 ($25,000.00) (“Allowance”) for
planning permitting and construction of the tenant improvements. This Allowance is intended to apply to all improvements required by Tenant. Any improvements above the Allowance shall be the responsibility of Optical Sensors Incorporated, d/b/a
Vasamed.  

  

	8.	Brokerage. Tenant represents to Landlord that Tenant has not dealt with any real estate broker, salesperson or finder in connection with this Amendment, and no other
such person initiated or participated in the negotiation of the Amendment or is entitled to any commission in connection herewith. Tenant hereby agrees to indemnify, defend and hold Landlord, its property manager and 

  

 2 

 their respective employees harmless from and against ay and all liabilities, claims, demands, actions,
damages, costs and expenses (including attorneys’ fees) arising from either (i) a claim for a fee or commission made by any broker, claiming to have acted by or on behalf of Tenant in connection with this Amendment, or (ii) a claim of, or right
to, lien under that statues of Minnesota relating to real estate broker liens with respect to any such broker retained by Tenant.  
  

	9.	Submission of Amendment. Submission of this Amendment to Tenant for signature does not constitute a reservation of space or an option to lease. This Amendment is not
effective until this Amendment, fully executed by the Landlord, has been delivered to Tenant.  

  

	10.	Full Force and Effect. Except as otherwise expressly set forth in this Eighth Amendment, all terms, provisions and covenants set forth in the Lease shall remain in
full force and effect and are hereby ratified and confirmed as of the date hereof. 

  

	11.	Conflicts. In the event that any of the terms, covenants and conditions of this Eighth Amendment conflict with any of the terms, covenants and conditions of the Lease,
the terms, covenants and conditions of this Seventh Amendment shall control. 

  
 IN WITNESS WHEREOF, the parties hereto have executed this Eighth Amendment as of the date and year first above written. 
  

							
	LANDLORD: FIRST INDUSTRIAL, L.P.	  	TENANT: OPTICAL SENSORS
	a Delaware Limited Partnership	  	INCORPORATED d/b/a Vasamed,
	 	 	 	  	a Delaware corporation
	By:	 	First Industrial Realty Trust, Inc., a	  	 	 	 
	 	 	Maryland corporation, its general partner	  	 	 	 
				
	By:	 	 /s/ Christopher Willson

	  	By:	 	 /s/ Paulita LaPlante

	Its:	 	Senior Regional Director	  	Its:	 	President & CEO

  

 3

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