Document:

Exhibit 10.12

 

 

November 13, 2020

 

Shane W. Kovacs

VIA EMAIL

 

		Re:	Employment Terms

 

Dear Shane:

 

As you know, you are currently employed
by Olema Pharmaceuticals, Inc. (the “Company”) as its Chief Financial Officer and Chief Operating Officer, pursuant
to the terms of an offer letter from the Company dated June 15, 2020 (the “Offer Letter”). In connection with
your continuing employment, you and the Company are hereby agreeing to the amended terms of employment set forth herein. The terms
set forth in this offer letter (“Agreement”) amend, restate, supersede and replace the terms set forth in the Offer
Letter in their entirety.

 

1.            Position;
Duties. You will remain employed as Chief Financial Officer and Chief Operating Officer,
reporting directly to the Company’s Chief Executive Officer. Your duties and responsibilities include oversight of the Finance,
Accounting, Corporate Communications and Investor Relations, Human Resources and Information Technology Departments and related
functions. You will work from New York, NY, subject to business travel, including the Company’s San Francisco, CA office.
You will be provided with a WeWork office or equivalent thereof in New York, where you are able to perform your duties. You agree
to devote your commercially reasonable efforts and full business time, skill and attention to the performance of your duties. You
are also required to adhere to the general employment policies and practices of the Company that may be in effect from time to
time, except that when the terms of this Agreement conflict with the Company’s general employment policies or practices,
this Agreement will control. The Company may change your position, duties, work location and compensation from time to time in
its discretion, subject to the terms and conditions set forth herein. You may participate
in outside charitable, civic, educational, professional, community or industry activities, and serve on the boards of for-profit
companies that do not compete with the Company, to the extent such activities do not individually or in the aggregate interfere
with your duties and responsibilities to the Company or create an actual or potential conflict of interest with the Company’s
business; provided, further,
that your service on any outside boards (whether for profit or non-profit) shall
require the prior consent of the Chief Executive Officer.

 

2.            Salary.
Your annual base salary will remain $400,000, less applicable deductions and withholdings,
payable in accordance with the Company’s payroll practices, as may be in effect from time to time.

 

3.            Benefits.
You will continue to be eligible to participate in the Company’s standard benefit programs, subject to the terms and conditions
of such plans. The Company may, from time to time, change these benefits in its discretion.

 

     

     

    

 

4.            Equity
Awards. You have previously been granted various equity interests in the Company (the
 “Awards”). Except as provided below in Section 6, the Awards will continue to be governed by the terms of the
existing plan documents, award agreements and grant notices. You will be eligible for future equity awards as determined by the
Company’s Board of Directors and/or its Compensation Committee (the “Board”).

 

5.            Performance
Bonuses. You will continue to be eligible to earn an annual incentive bonus, with a target
equal to 35% of your annual base salary. Whether you receive a bonus, and the amount of any such bonus, shall be determined by
the Board in its reasonable discretion, and shall be based upon achievement of performance objectives to be mutually agreed upon
between you and the Chief Executive Officer and other criteria to be determined by the Board. Any annual bonus shall be paid within
30 days after the Board’s determination that a bonus shall be awarded and in any event shall be paid by March 15 for
the immediately preceding year. If your employment terminates for any reason prior to the end of the calendar year, then you will
not have earned a bonus for that year and will not receive any portion of it. Notwithstanding the foregoing, if your employment
is terminated by the Company without Cause (as defined below), or you resign for Good Reason (as defined below), in either case
after the end of a calendar year, but before the bonus for that year has been paid, then you will remain eligible to receive a
bonus for that preceding year, to be awarded and paid on the same terms as the remaining executive team.

 

6.            At-Will
Employment; Severance.

 

(a)           At-Will
Employment. Your employment with Company will remain “at-will.” This means
that either you or Company may terminate your employment at any time, with or without Cause (as defined below), and with or without
advance notice.

 

(b)           Termination
For Cause; Resignation Without Good Reason. If, at any time, the Company terminates your
employment for Cause (as defined below), or if you resign without Good Reason (as defined below), or if your employment terminates
as a result of your death or disability, you will receive (i) your base salary accrued through your last day of employment,
(ii) any unused vacation (if applicable) accrued through your last day of employment, (iii) reimbursement for any business
expenses incurred by you consistent with the Company policy through your last day of employment and (iv) amounts, if any,
accrued under the terms of the Company’s benefit plans through your last day of employment (collectively, “Accrued
Obligations”). Under these circumstances, you will not be entitled to any other form of compensation from the Company, including
severance benefits.

 

    

     

    

 

(c)            Termination
without Cause or Resignation for Good Reason Unrelated to Change in Control. If, at any
time outside the Change in Control Period (as defined below), the Company terminates your employment without Cause, or you resign
for Good Reason, and other than as a result of your death or disability, and provided such termination constitutes a “separation
from service” (as defined under Treasury Regulation Section 1.409A-1(h), without regard to any alternative definition
thereunder, a “Separation from Service”), then in addition to the Accrued Obligations and subject to the preconditions
set forth in Section 7 below, you shall be entitled to receive the following severance benefits:

  

(i)            The
Company will pay you an amount equal to 12 months of your then-current base salary (excluding any salary reduction that served
as the basis for any Good Reason resignation), less all applicable withholdings and deductions, paid over such 12-month period,
on the schedule described in Section 7 below.

 

(ii)            You
will remain eligible for an annual bonus for the year in which your Separation from Service is effective, with the bonus amount
to be determined by the Board (or the Compensation Committee thereof) based on corporate performance during the year, and then
prorated based on your months of service during the applicable bonus year. Any bonus awarded will be subject to deductions and
withholdings and paid at the same time as when bonuses are paid to the rest of senior management.

 

(iii)            If
you timely elect continued coverage under COBRA for yourself and your covered dependents under the Company’s group health
plans following such termination or resignation of employment, then the Company shall pay the entire COBRA premiums necessary to
continue your health insurance coverage in effect for yourself and your eligible dependents on the termination date until the earliest
of (A) the close of the 12 month period following the termination of your employment, (B) the expiration of your eligibility
for the continuation coverage under COBRA, and (C) the date when you become eligible for substantially equivalent health insurance
coverage in connection with new employment. If you become eligible for coverage under another employer's group health plan or otherwise
cease to be eligible for COBRA during the period provided in this clause, you must immediately notify the Company of such event,
and all payments and obligations under this clause shall cease.

 

(iv)            In
the event your separation occurs after you complete one year of service with the Company, then the Company will accelerate the
vesting of any time-based equity awards that were granted to you in connection with the commencement of your employment such that
50% of the then unvested time-based equity grants shall be deemed vested as of your last day of employment; and in the event your
separation occurs within 12 months following the initial public offering of the Company’s shares, then the Company will accelerate
the vesting of any time-based equity awards that were granted to you in connection with the commencement of your employment such
that 100% of the then unvested time-based equity grants shall be deemed vested as of your last day of employment.

 

(d)          Termination
without Cause or Resignation for Good Reason In Connection With Change in Control. If,
at any time within the Change in Control Period (as defined below), the Company terminates your employment without Cause, or you
resign for Good Reason, and other than as a result of your death or disability, and provided such termination constitutes a Separation
from Service, then in addition to the Accrued Obligations and subject to the preconditions set forth in Section 7 below, you
shall be entitled to receive the following severance benefits:

 

(i)            The
Company will pay you a lump-sum amount within 60 days of your last day of employment equal to 12 months of your then-current base
salary plus your target bonus for the year in which your termination occurs (less deductions and withholdings)(excluding any salary
or bonus reduction that served as the basis for any Good Reason resignation).

 

     

     

    

 

(ii)            You
will remain eligible for an annual bonus for the year in which your Separation from Service is effective, with the bonus amount
to be determined by the Board (or the Compensation Committee thereof) based on corporate performance during the year, and then
prorated based on your months of service during the applicable bonus year. Any bonus awarded will be subject to deductions and
withholdings and paid at the same time as when bonuses are paid to the rest of senior management.

 

(iii)            If
you timely elect continued coverage under COBRA for yourself and your covered dependents under the Company’s group health
plans following such termination or resignation of employment, then the Company shall pay the entire COBRA premiums necessary to
continue your health insurance coverage in effect for yourself and your eligible dependents on the termination date until the earliest
of (A) the close of the 12 month period following the termination of your employment, (B) the expiration of your eligibility
for the continuation coverage under COBRA, and (C) the date when you become eligible for substantially equivalent health insurance
coverage in connection with new employment. If you become eligible for coverage under another employer’s group health plan
or otherwise cease to be eligible for COBRA during the period provided in this clause, you must immediately notify the Company
of such event, and all payments and obligations under this clause shall cease; and

 

(iv)            The
Company will accelerate the time-based vesting of your equity grants such that you will be deemed fully vested as to service in
all such shares.

 

7.            Severance
Conditions. Your receipt of the severance benefits set forth in Section 6 is conditional
upon (a) your continuing to comply with your obligations under your Employee Proprietary Information and Invention Assignment
Agreement; and (b) your delivering to the Company an effective, general release of claims in favor of the Company, that does
not require you to release your right to the severance benefits or your right to be indemnified against third party claims, and
does not impose any additional restrictive covenants on your activities following termination, within 60 days following your termination
date. The salary continuation set forth in Section 6(c)(i) will be paid in equal installments on the Company’s
regular payroll schedule and will be subject to applicable tax withholdings over the period outlined above following the date of
your termination date; provided, however, that no payments will be made prior to the 60th day following your Separation from Service.
On the 60th day following your Separation from Service, the Company will pay you in a lump sum the salary continuation that you
would have received on or prior to such date under the original schedule but for the delay while waiting for the 60th day in compliance
with Section 409A (“Section 409A”) of the Internal Revenue Code of 1986, as amended (the “Code”)
and the effectiveness of the release, with the balance of the salary continuation being paid as originally scheduled.

 

8.            Definitions.

 

(a)            Cause.
For purposes of this Agreement, “Cause” means any of the following: (i) theft,
breach of fiduciary duty, or intentional falsification of Company documents or records; (ii) material failure to abide by
any Company policy after written notice from the Company regarding failure to abide by such policy; (iii) intentional and
unauthorized use, misappropriation, destruction or diversion of any material tangible or intangible asset or corporate opportunity
of the Company (including, without limitation, improper use or disclosure of the Company’s confidential or proprietary information);
(iv) any intentional act that has a material detrimental effect on the Company’s reputation or business; (v) repeated
failure or inability to perform any reasonable assigned duties after written notice from the Company of, and a reasonable opportunity
to cure, such failure or inability; (vi) any material breach of any contractual or legal obligation to the Company and the
failure to cure within ten days after delivery of written notice thereof (to the extent such breach or violation is curable); or
(vii) conviction (including any plea of guilty or nolo contendere) of any felony.

 

     

     

    

 

(b)            Good
Reason. For purposes of this Agreement, “Good Reason” shall mean that you
have resigned based on the occurrence of any of the following events: (i) a material diminution in your total target cash
compensation (base salary and target bonus) of more than 10% except for across-the-board salary reductions similarly affecting
all or substantially all senior executives of the Company; (ii) a change in the geographic location of your primary place
of work that results in an increase in your one-way commute by more than 25 miles (provided, however, that this subclause (ii) shall
only be applicable after the Company resumes normal in-person office operations in connection with the COVID-19 pandemic); (iii) a
material reduction in your job duties or responsibilities reporting directly to the Chief Executive Officer; provided, however,
that you shall not be deemed to have Good Reason if the Company survives as a separate legal entity following a Change in Control
and you hold materially the same position in such legal entity as before the Change in Control; or (iv) a material breach
of this Agreement by the Company. A resignation will only be for Good Reason if you deliver written notice of such condition to
the Company within 30 days after the initial occurrence of such condition, the Company has failed to cure such condition within
30 days after the delivery of such notice, and you in fact resign within 45 days after you deliver the initial notice.

 

(c)            Change
in Control. For purposes of this Agreement, “Change in Control” means (i) a
sale of all or substantially all of the Company’s assets other than to an Excluded Entity (as defined below); (ii) a
merger, consolidation or other capital reorganization or business combination transaction of the Company with or into another corporation,
limited liability company or other entity other than an Excluded Entity; or (iii) the consummation of a transaction, or series
of related transactions, in which any “person” (as such term is used in Sections 13(d) and 14(d) of the Securities
Exchange Act of 1934, as amended) becomes the “beneficial owner” (as defined in Rule 13d-3 of the Securities Exchange
Act of 1934, as amended), directly or indirectly, of all of the Company’s then outstanding voting securities. An “Excluded
Entity” means a corporation or other entity of which the holders of voting capital stock of the Company outstanding immediately
prior to such transaction are the direct or indirect holders of voting securities representing a majority of the votes entitled
to be cast by all of such corporation’s or other entity’s voting securities outstanding immediately after such transaction.

 

(d)            Change
in Control Period. For purposes of this Agreement, the “Change in Control Period”
shall be the period starting three months before the effective date of a Change in Control and extending through the period ending
18 months following the effective date of a Change in Control.

 

     

     

    

 

9.          Section 409A.
The payments and benefits under this Agreement are intended to qualify for exemptions from the application of Section 409A
and this Agreement will be construed to the greatest extent possible as consistent with those provisions, and to the extent not
so exempt, this Agreement (and any definitions hereunder) will be construed in a manner that complies with Section 409A to
the extent necessary to avoid adverse taxation under Section 409A. Notwithstanding anything to the contrary herein, to the
extent required to comply with Section 409A, a termination of employment shall not be deemed to have occurred for purposes
of any provision of this Agreement providing for the payment of amounts or benefits upon or following a termination of employment
unless such termination is also a Separation from Service. Your right to receive any installment payments will be treated as a
right to receive a series of separate payments and, accordingly, each installment payment shall at all times be considered a separate
and distinct payment. Notwithstanding any provision to the contrary in this Agreement, if you are deemed by the Company at the
time of your Separation from Service to be a “specified employee” for purposes of Section 409A, and if any of
the payments upon Separation from Service set forth herein and/or under any other agreement with the Company are deemed to be “deferred
compensation,” then, to the extent delayed commencement of any portion of such payments is required in order to avoid a prohibited
distribution under Section 409A and the related adverse taxation under Section 409A, such payments shall not be provided
to you prior to the earliest of (a) the expiration of the six-month period measured from the date of Separation from Service,
(b) the date of your death or (c) such earlier date as permitted under Section 409A without the imposition of adverse
taxation. With respect to payments to be made upon execution of an effective release, if the release revocation period spans two
calendar years, payments will be made in the second of the two calendar years to the extent necessary to avoid adverse taxation
under Section 409A. With respect to reimbursements or in-kind benefits provided hereunder (or otherwise) that are not exempt
from Section 409A, the following rules shall apply: (x) the amount of expenses eligible for reimbursement, or in-kind
benefits provided, during any one taxable year shall not affect the expenses eligible for reimbursement, or in-kind benefit to
be provided in any other taxable year, (y) in the case of any reimbursements of eligible expenses, reimbursement shall be
made on or before the last day of the taxable year following the taxable year in which the expense was incurred and (z) the
right to reimbursement or in-kind benefits shall not be subject to liquidation or exchange for another benefit.

 

10.          280G.

 

(a)            If
any payment or benefit you will or may receive from the Company or from another source (a “280G Payment”) would
(i) constitute a “parachute payment” within the meaning of Section 280G of the Code, and (ii) but for
this sentence, be subject to the excise tax imposed by Section 4999 of the Code (the “Excise Tax”), then any such
280G Payment pursuant to this Agreement (a “Payment”) shall be equal to the Reduced Amount. The “Reduced Amount”
shall be the largest portion, up to and including the total, of the Payment after taking into account all applicable federal, state
and local employment taxes, income taxes, and the Excise Tax (all computed at the highest applicable marginal rate), that results
in your receipt, on an after-tax basis, of the greater economic benefit notwithstanding that all or some portion of the Payment
may be subject to the Excise Tax. If more than one method of reduction will result in the same economic benefit, the items so reduced
will be reduced pro rata (the “Pro Rata Reduction Method”).

 

     

     

    

 

(b)            Notwithstanding
any provision of paragraph (a) to the contrary, if the reduction method or the Pro Rata Reduction Method would result in any
portion of the Payment being subject to taxes pursuant to Section 409A that would not otherwise be subject to taxes pursuant
to Section 409A, then the reduction method and/or the Pro Rata Reduction Method, as the case may be, shall be modified so
as to avoid the imposition of taxes pursuant to Section 409A as follows: (A) as a first priority, the modification shall
preserve to the greatest extent possible, the greatest economic benefit for you as determined on an after-tax basis; (B) as
a second priority, Payments that are contingent on future events (e.g., being terminated without cause), shall be reduced (or eliminated)
before Payments that are not contingent on future events; and (C) as a third priority, Payments that are “deferred compensation”
within the meaning of Section 409A of the Code shall be reduced (or eliminated) before Payments that are not deferred compensation
within the meaning of Section 409A of the Code.

 

11.           Confidentiality
Obligations. You are required to remain in compliance with the terms of your Employee
Proprietary Information and Invention Assignment Agreement.

 

12.           Arbitration.
To ensure the timely and economical resolution of disputes that may arise between you and the Company, both you and the Company
mutually agree that pursuant to the Federal Arbitration Act, 9 U.S.C. §1-16, and to the fullest extent permitted by applicable
law, you will submit solely to final, binding and confidential arbitration any and all disputes, claims, or causes of action arising
from or relating to: the negotiation, execution, interpretation, performance, breach or enforcement of this Agreement; or your
employment with the Company (including but not limited to all statutory claims); or the termination of your employment with the
Company (including but not limited to all statutory claims). BY AGREEING TO THIS ARBITRATION PROCEDURE, BOTH YOU AND THE COMPANY
WAIVE THE RIGHT TO RESOLVE ANY SUCH DISPUTES THROUGH A TRIAL BY JURY OR JUDGE OR THROUGH AN ADMINISTRATIVE PROCEEDING. The Arbitrator
shall have the sole and exclusive authority to determine whether a dispute, claim or cause of action is subject to arbitration
under this section and to determine any procedural questions which grow out of such disputes, claims or causes of action and bear
on their final disposition. All claims, disputes, or causes of action under this section, whether by you or the Company, must be
brought solely in an individual capacity, and shall not be brought as a plaintiff (or claimant) or class member in any purported
class or representative proceeding, nor joined or consolidated with the claims of any other person or entity. The Arbitrator may
not consolidate the claims of more than one person or entity, and may not preside over any form of representative or class proceeding.
To the extent that the preceding sentences in this paragraph are found to violate applicable law or are otherwise found unenforceable,
any claim(s) alleged or brought on behalf of a class shall proceed in a court of law rather than by arbitration. Any arbitration
proceeding under this Arbitration section shall be presided over by a single arbitrator and conducted by JAMS, Inc. (“JAMS”)
in San Francisco, CA under the then applicable JAMS rules for the resolution of employment disputes (available upon request
and also currently available at http://www.jamsadr.com/rules-employment-arbitration/). You and the Company both have the right
to be represented by legal counsel at any arbitration proceeding, at each party’s own expense. The Arbitrator shall: (a) have
the authority to compel adequate discovery for the resolution of the dispute; (b) issue a written arbitration decision, to
include the arbitrator’s essential findings and conclusions and a statement of the award; and (c) be authorized to award
any or all remedies that you or the Company would be entitled to seek in a court of law. The Company shall pay all JAMS arbitration
fees in excess of the amount of court fees that would be required of you if the dispute were decided in a court of law. This section
shall not apply to any action or claim that cannot be subject to mandatory arbitration as a matter of law, including, without limitation,
claims brought pursuant to the California Private Attorneys General Act of 2004, as amended, the California Fair Employment and
Housing Act, as amended, and the California Labor Code, as amended, to the extent such claims are not permitted by applicable law
to be submitted to mandatory arbitration and such applicable law is not preempted by the Federal Arbitration Act or otherwise invalid
(collectively, the “Excluded Claims”). In the event you intend to bring multiple claims, including one of the Excluded
Claims listed above, the Excluded Claims may be filed with a court, while any other claims will remain subject to mandatory arbitration.
Nothing in this section is intended to prevent either you or the Company from obtaining injunctive relief in court to prevent irreparable
harm pending the conclusion of any such arbitration. Any final award in any arbitration proceeding hereunder may be entered as
a judgment in the federal and state courts of any competent jurisdiction and enforced accordingly.

 

     

     

    

 

13.            Miscellaneous.
This Agreement (including the agreements and documents referenced herein) is the complete
and exclusive statement of your agreement with the Company on the subject matters herein, and supersedes and replaces any and all
prior agreements or representations with regard to the subject matter hereof, whether written or oral (including those set forth
in the Offer Letter). It is entered into without reliance on any promise or representation other than those expressly contained
herein, and it cannot be modified, amended or extended except in a writing signed by you and a duly authorized member of the Board.
This Agreement is intended to bind and inure to the benefit of and be enforceable by you and the Company, and our respective successors,
assigns, heirs, executors and administrators, except that you may not assign any of your duties or rights hereunder without the
express written consent of the Company. Whenever possible, each provision of this Agreement will be interpreted in such manner
as to be effective and valid under applicable law, but if any provision of this Agreement is held to be invalid, illegal or unenforceable
in any respect under any applicable law or rule in any jurisdiction, such invalidity, illegality or unenforceability will
not affect any other provision or any other jurisdiction, but this Agreement will be reformed, construed and enforced as if such
invalid, illegal or unenforceable provisions had never been contained herein. This Agreement and the terms of your employment with
the Company shall be governed in all aspects by the laws of the State of California.

 

     

     

    

 

If you agree to the terms and conditions
set forth herein, please sign below.

 

Best regards,

 

	/s/ Sean Bohen	 
	Sean Bohen, M.D., Ph.D.	 
	Chief Executive Officer	 
	 
	Accepted and agreed:
	 
	/s/ Shane W. Kovacs	 
	Shane W. Kovacs	 
	 
	Date: November 14, 2020Exhibit 10.13

 

 

 

November 13, 2020

 

Peter Kushner

 

VIA EMAIL

 

		Re:	Employment Terms

 

Dear Peter:

 

As you know, you are currently employed
by Olema Pharmaceuticals, Inc. (the “Company”) as its Chief Scientific Officer, pursuant to the terms of an offer
letter from the Company dated June 15, 2020 (the “Offer Letter”). In connection with your continuing employment,
you and the Company are hereby agreeing to the amended terms of employment set forth herein. The terms set forth in this offer
letter (“Agreement”) amend, restate, supersede and replace the terms set forth in the Offer Letter in their entirety.

 

1.            Position;
Duties. You will remain employed as Chief Scientific Officer, reporting directly to the
Company’s Chief Executive Officer, based in the Company’s San Francisco area offices or at other locations as mutually
agreed. You agree to devote your commercially reasonable efforts and full business time, skill and attention to the performance
of your duties. You are also required to adhere to the general employment policies and practices of the Company that may be in
effect from time to time, except that when the terms of this Agreement conflict with the Company’s general employment policies
or practices, this Agreement will control. The Company may change your position, duties, work location and compensation from time
to time in its discretion, subject to the terms and conditions set forth herein.

 

2.            Salary.
Your annual base salary will remain $350,000, less applicable deductions and withholdings,
payable in accordance with the Company’s payroll practices, as may be in effect from time to time.

 

3.            Benefits.
You will continue to be eligible to participate in the Company’s standard benefit programs, subject to the terms and conditions
of such plans. The Company may, from time to time, change these benefits in its discretion.

 

4.            Equity
Awards. You have previously been granted various equity interests in the Company (the
 “Awards”). The Awards will continue to be governed by the terms of the existing plan documents, award agreements and
grant notices. You will be eligible for future equity awards as determined by the Company’s Board of Directors and/or its
Compensation Committee (the “Board”).

 

     

     

    

 

5.            Performance
Bonuses. You will continue to be eligible to earn an annual incentive bonus, with a target
equal to 30% of your annual base salary. Whether you receive a bonus, and the amount of any such bonus, shall be determined by
the Board in its reasonable discretion, and shall be based upon achievement of performance objectives to be mutually agreed upon
between you and the Chief Executive Officer and other criteria to be determined by the Board. Any annual bonus shall be paid within
30 days after the Board’s determination that a bonus shall be awarded and in any event shall be paid by March 15 for
the immediately preceding year. If your employment terminates for any reason prior to the end of the calendar year, then you will
not have earned a bonus for that year and will not receive any portion of it. Notwithstanding the foregoing, if your employment
is terminated by the Company without Cause (as defined below), or you resign for Good Reason (as defined below), in either case
after the end of a calendar year, but before the bonus for that year has been paid, then you will remain eligible to a bonus for
that preceding year, to be awarded and paid on the same terms as the remaining executive team.

 

6.            At
Will Employment; Severance.

 

(a)            At-Will
Employment. Your employment with Company will remain “at-will.” This means
that either you or Company may terminate your employment at any time, with or without Cause (as defined below), and with or without
advance notice.

 

(b)            Termination
For Cause; Resignation Without Good Reason. If, at any time, the Company terminates your
employment for Cause (as defined herein), or if you resign without Good Reason (as defined below), or if your employment terminates
as a result of your death or disability, you will receive your base salary accrued through your last day of employment, as well
as any unused vacation (if applicable) accrued through your last day of employment. Under these circumstances, you will not be
entitled to any other form of compensation from the Company, including severance benefits.

 

(c)            Termination
without Cause or Resignation for Good Reason Unrelated to Change in Control. If, at any
time outside the Change in Control Period (as defined below), the Company terminates your employment without Cause, or you resign
for Good Reason, and other than as a result of your death or disability, and provided such termination constitutes a “separation
from service” (as defined under Treasury Regulation Section 1.409A-1(h), without regard to any alternative definition
thereunder, a “Separation from Service”), then subject to the preconditions set forth in Section 7 below, you
shall be entitled to receive the following severance benefits:

 

(i)            The
Company will pay you an amount equal to 12 months of your then-current base salary (excluding any salary reduction that served
as the basis for any Good Reason resignation), less all applicable withholdings and deductions, paid over such 12-month period,
on the schedule described in Section 7 below.

 

(ii)           You
will remain eligible for an annual bonus for the year in which your Separation from Service is effective, with the bonus amount
to be determined by the Board (or the Compensation Committee thereof) based on corporate performance during the year, and then
prorated based on your months of service during the applicable bonus year. Any bonus awarded will be subject to deductions and
withholdings and paid at the same time as when bonuses are paid to the rest of senior management.

 

     

     

    

 

(iii)          If
you timely elect continued coverage under COBRA for yourself and your covered dependents under the Company’s group health
plans following such termination or resignation of employment, then the Company shall pay the entire COBRA premiums necessary to
continue your health insurance coverage in effect for yourself and your eligible dependents on the termination date until the earliest
of (A) the close of the 12 month period following the termination of your employment, (B) the expiration of your eligibility
for the continuation coverage under COBRA, and (C) the date when you become eligible for substantially equivalent health insurance
coverage in connection with new employment. If you become eligible for coverage under another employer's group health plan or otherwise
cease to be eligible for COBRA during the period provided in this clause, you must immediately notify the Company of such event,
and all payments and obligations under this clause shall cease.

 

(iii)            The
Company will accelerate the vesting of the option award that was granted to you in connection with the commencement of your employment
such that 50% of the then unvested shares shall be deemed vested and exercisable; and in the event your separation occurs within
12 months following the initial public offering of the Company’s shares, then the Company will accelerate the vesting of
the option award that was granted to you in connection with the commencement of your employment such that 100% of the then unvested
shares shall be deemed vested and exercisable.

 

(d)            Termination
without Cause or Resignation for Good Reason In Connection With Change in Control. If,
at any time within the Change in Control Period (as defined below), the Company terminates your employment without Cause, or you
resign for Good Reason, and other than as a result of your death or disability, and provided such termination constitutes a Separation
from Service, then subject to the preconditions set forth in Section 7 below, you shall be entitled to receive the following
severance benefits:

 

(i)            The
Company will pay you a lump-sum amount equal to 12 months of your then-current base salary plus your target bonus for the year
in which your termination occurs (less deductions and withholdings)(excluding any salary or bonus reduction that served as the
basis for any Good Reason resignation).

 

(ii)            You
will remain eligible for an annual bonus for the year in which your Separation from Service is effective, with the bonus amount
to be determined by the Board (or the Compensation Committee thereof) based on corporate performance during the year, and then
prorated based on your months of service during the applicable bonus year. Any bonus awarded will be subject to deductions and
withholdings and paid at the same time as when bonuses are paid to the rest of senior management.

 

(iii)         If
you timely elect continued coverage under COBRA for yourself and your covered dependents under the Company’s group health
plans following such termination or resignation of employment, then the Company shall pay the entire COBRA premiums necessary to
continue your health insurance coverage in effect for yourself and your eligible dependents on the termination date until the earliest
of (A) the close of the 12 month period following the termination of your employment, (B) the expiration of your eligibility
for the continuation coverage under COBRA, and (C) the date when you become eligible for substantially equivalent health insurance
coverage in connection with new employment. If you become eligible for coverage under another employer’s group health plan
or otherwise cease to be eligible for COBRA during the period provided in this clause, you must immediately notify the Company
of such event, and all payments and obligations under this clause shall cease; and

 

     

     

    

 

(iii)          The
Company will accelerate the time-based vesting of your equity grants such that you will be deemed fully vested as to service in
all such shares.

 

7.            Severance
Conditions. Your receipt of the severance benefits set forth in Section 6 is conditional
upon (a) your continuing to comply with your obligations under your Employee Proprietary Information and Invention Assignment
Agreement; and (b) your delivering to the Company an effective, general release of claims in favor of the Company within 60
days following your termination date. The salary continuation set forth in Section 6(c)(i) will be paid in equal installments
on the Company’s regular payroll schedule and will be subject to applicable tax withholdings over the period outlined above
following the date of your termination date; provided, however, that no payments will be made prior to the 60th day following your
Separation from Service. On the 60th day following your Separation from Service, the Company will pay you in a lump sum the salary
continuation that you would have received on or prior to such date under the original schedule but for the delay while waiting
for the 60th day in compliance with Section 409A (“Section 409A”) of the Internal Revenue Code of 1986, as
amended (the “Code”) and the effectiveness of the release, with the balance of the salary continuation being paid as
originally scheduled.

 

8.            Definitions.

 

(a)            Cause.
For purposes of this Agreement, “Cause” means any of the following: (i) theft,
breach of fiduciary duty, or intentional falsification of Company documents or records; (ii) material failure to abide by
any Company policy after written notice from the Company regarding failure to abide by such policy; (iii) intentional and
unauthorized use, misappropriation, destruction or diversion of any material tangible or intangible asset or corporate opportunity
of the Company (including, without limitation, improper use or disclosure of the Company’s confidential or proprietary information);
(iv) any intentional act that has a material detrimental effect on the Company’s reputation or business; (v) repeated
failure or inability to perform any reasonable assigned duties after written notice from the Company of, and a reasonable opportunity
to cure, such failure or inability; (vi) any material breach of any contractual or legal obligation to the Company and the
failure to cure within ten days after delivery of written notice thereof (to the extent such breach or violation is curable); or
(vii) conviction (including any plea of guilty or nolo contendere) of any felony.

 

     

     

    

 

(b)            Good
Reason. For purposes of this Agreement, “Good Reason” shall mean that you
have resigned based on the occurrence of any of the following events: (i) a material diminution in your total target cash
compensation (base and bonus) of more than 10% except for across-the-board salary reductions similarly affecting all or substantially
all senior executives of the Company; (ii) a change in the geographic location of your primary place of work that results
in an increase in your one-way commute by more than 25 miles (provided, however, that this subclause (ii) shall only be applicable
after the Company resumes normal in-person office operations in connection with the COVID-19 pandemic); (iii) a material reduction
in your job duties or responsibilities reporting directly to the Chief Executive Officer; or (iv) a material breach of this
Agreement by the Company; provided, however, that you shall not be deemed to have Good Reason if the Company survives as a separate
legal entity following a Change in Control and you hold materially the same position in such legal entity as before the Change
in Control. A resignation will only be for Good Reason if you deliver written notice of such condition to the Company within 30
days after the initial occurrence of such condition, the Company has failed to cure such condition within 30 days after the delivery
of such notice, and you in fact resign within 45 days after you deliver the initial notice.

 

(c)            Change
in Control. For purposes of this Agreement, “Change in Control” means (i) a
sale of all or substantially all of the Company’s assets other than to an Excluded Entity (as defined below); (ii) a
merger, consolidation or other capital reorganization or business combination transaction of the Company with or into another corporation,
limited liability company or other entity other than an Excluded Entity; or (iii) the consummation of a transaction, or series
of related transactions, in which any “person” (as such term is used in Sections 13(d) and 14(d) of the Securities
Exchange Act of 1934, as amended) becomes the “beneficial owner” (as defined in Rule 13d-3 of the Securities Exchange
Act of 1934, as amended), directly or indirectly, of all of the Company’s then outstanding voting securities. An “Excluded
Entity” means a corporation or other entity of which the holders of voting capital stock of the Company outstanding immediately
prior to such transaction are the direct or indirect holders of voting securities representing a majority of the votes entitled
to be cast by all of such corporation’s or other entity’s voting securities outstanding immediately after such transaction.

 

(d)            Change
in Control Period. For purposes of this Agreement, the “Change in Control Period”
shall be the period starting three months before the effective date of a Change in Control and extending through the period ending
18 months following the effective date of a Change in Control.

 

9.            Section 409A.
The payments and benefits under this Agreement are intended to qualify for exemptions from the application of Section 409A
and this Agreement will be construed to the greatest extent possible as consistent with those provisions, and to the extent not
so exempt, this Agreement (and any definitions hereunder) will be construed in a manner that complies with Section 409A to
the extent necessary to avoid adverse taxation under Section 409A. Notwithstanding anything to the contrary herein, to the
extent required to comply with Section 409A, a termination of employment shall not be deemed to have occurred for purposes
of any provision of this Agreement providing for the payment of amounts or benefits upon or following a termination of employment
unless such termination is also a Separation from Service. Your right to receive any installment payments will be treated as a
right to receive a series of separate payments and, accordingly, each installment payment shall at all times be considered a separate
and distinct payment. Notwithstanding any provision to the contrary in this Agreement, if you are deemed by the Company at the
time of your Separation from Service to be a “specified employee” for purposes of Section 409A, and if any of
the payments upon Separation from Service set forth herein and/or under any other agreement with the Company are deemed to be “deferred
compensation,” then, to the extent delayed commencement of any portion of such payments is required in order to avoid a prohibited
distribution under Section 409A and the related adverse taxation under Section 409A, such payments shall not be provided
to you prior to the earliest of (a) the expiration of the six-month period measured from the date of Separation from Service,
(b) the date of your death or (c) such earlier date as permitted under Section 409A without the imposition of adverse
taxation. With respect to payments to be made upon execution of an effective release, if the release revocation period spans two
calendar years, payments will be made in the second of the two calendar years to the extent necessary to avoid adverse taxation
under Section 409A. With respect to reimbursements or in-kind benefits provided hereunder (or otherwise) that are not exempt
from Section 409A, the following rules shall apply: (x) the amount of expenses eligible for reimbursement, or in-kind
benefits provided, during any one taxable year shall not affect the expenses eligible for reimbursement, or in-kind benefit to
be provided in any other taxable year, (y) in the case of any reimbursements of eligible expenses, reimbursement shall be
made on or before the last day of the taxable year following the taxable year in which the expense was incurred and (z) the
right to reimbursement or in-kind benefits shall not be subject to liquidation or exchange for another benefit.

 

     

     

    

 

10.          280G.

 

(a)            If
any payment or benefit you will or may receive from the Company or from another source (a “280G Payment”) would
(i) constitute a “parachute payment” within the meaning of Section 280G of the Code, and (ii) but for
this sentence, be subject to the excise tax imposed by Section 4999 of the Code (the “Excise Tax”), then any such
280G Payment pursuant to this Agreement (a “Payment”) shall be equal to the Reduced Amount. The “Reduced Amount”
shall be the largest portion, up to and including the total, of the Payment after taking into account all applicable federal, state
and local employment taxes, income taxes, and the Excise Tax (all computed at the highest applicable marginal rate), that results
in your receipt, on an after-tax basis, of the greater economic benefit notwithstanding that all or some portion of the Payment
may be subject to the Excise Tax. If more than one method of reduction will result in the same economic benefit, the items so reduced
will be reduced pro rata (the “Pro Rata Reduction Method”).

 

(b)            Notwithstanding
any provision of paragraph (a) to the contrary, if the reduction method or the Pro Rata Reduction Method would result in any
portion of the Payment being subject to taxes pursuant to Section 409A that would not otherwise be subject to taxes pursuant
to Section 409A, then the reduction method and/or the Pro Rata Reduction Method, as the case may be, shall be modified so
as to avoid the imposition of taxes pursuant to Section 409A as follows: (A) as a first priority, the modification shall
preserve to the greatest extent possible, the greatest economic benefit for you as determined on an after-tax basis; (B) as
a second priority, Payments that are contingent on future events (e.g., being terminated without cause), shall be reduced (or eliminated)
before Payments that are not contingent on future events; and (C) as a third priority, Payments that are “deferred compensation”
within the meaning of Section 409A of the Code shall be reduced (or eliminated) before Payments that are not deferred compensation
within the meaning of Section 409A of the Code.

 

     

     

    

 

11.          Confidentiality
Obligations. You are required to remain in compliance with the terms of your Employee
Proprietary Information and Invention Assignment Agreement.

 

12.          Arbitration.
To ensure the timely and economical resolution of disputes that may arise between you and the Company, both you and the Company
mutually agree that pursuant to the Federal Arbitration Act, 9 U.S.C. §1-16, and to the fullest extent permitted by applicable
law, you will submit solely to final, binding and confidential arbitration any and all disputes, claims, or causes of action arising
from or relating to: the negotiation, execution, interpretation, performance, breach or enforcement of this Agreement; or your
employment with the Company (including but not limited to all statutory claims); or the termination of your employment with the
Company (including but not limited to all statutory claims). BY AGREEING TO THIS ARBITRATION PROCEDURE, BOTH YOU AND THE COMPANY
WAIVE THE RIGHT TO RESOLVE ANY SUCH DISPUTES THROUGH A TRIAL BY JURY OR JUDGE OR THROUGH AN ADMINISTRATIVE PROCEEDING. The Arbitrator
shall have the sole and exclusive authority to determine whether a dispute, claim or cause of action is subject to arbitration
under this section and to determine any procedural questions which grow out of such disputes, claims or causes of action and bear
on their final disposition. All claims, disputes, or causes of action under this section, whether by you or the Company, must be
brought solely in an individual capacity, and shall not be brought as a plaintiff (or claimant) or class member in any purported
class or representative proceeding, nor joined or consolidated with the claims of any other person or entity. The Arbitrator may
not consolidate the claims of more than one person or entity, and may not preside over any form of representative or class proceeding.
To the extent that the preceding sentences in this paragraph are found to violate applicable law or are otherwise found unenforceable,
any claim(s) alleged or brought on behalf of a class shall proceed in a court of law rather than by arbitration. Any arbitration
proceeding under this Arbitration section shall be presided over by a single arbitrator and conducted by JAMS, Inc. (“JAMS”)
in San Francisco, CA under the then applicable JAMS rules for the resolution of employment disputes (available upon request
and also currently available at http://www.jamsadr.com/rules-employment-arbitration/). You and the Company both have the right
to be represented by legal counsel at any arbitration proceeding, at each party’s own expense. The Arbitrator shall: (a) have
the authority to compel adequate discovery for the resolution of the dispute; (b) issue a written arbitration decision, to
include the arbitrator’s essential findings and conclusions and a statement of the award; and (c) be authorized to award
any or all remedies that you or the Company would be entitled to seek in a court of law. The Company shall pay all JAMS arbitration
fees in excess of the amount of court fees that would be required of you if the dispute were decided in a court of law. This section
shall not apply to any action or claim that cannot be subject to mandatory arbitration as a matter of law, including, without limitation,
claims brought pursuant to the California Private Attorneys General Act of 2004, as amended, the California Fair Employment and
Housing Act, as amended, and the California Labor Code, as amended, to the extent such claims are not permitted by applicable law
to be submitted to mandatory arbitration and such applicable law is not preempted by the Federal Arbitration Act or otherwise invalid
(collectively, the “Excluded Claims”). In the event you intend to bring multiple claims, including one of the Excluded
Claims listed above, the Excluded Claims may be filed with a court, while any other claims will remain subject to mandatory arbitration.
Nothing in this section is intended to prevent either you or the Company from obtaining injunctive relief in court to prevent irreparable
harm pending the conclusion of any such arbitration. Any final award in any arbitration proceeding hereunder may be entered as
a judgment in the federal and state courts of any competent jurisdiction and enforced accordingly.

 

     

     

    

 

13.          Miscellaneous.
This Agreement (including the agreement referenced herein) is the complete and exclusive
statement of your agreement with the Company on the subject matters herein, and supersedes and replaces any and all prior agreements
or representations with regard to the subject matter hereof, whether written or oral (including those set forth in the Offer Letter).
It is entered into without reliance on any promise or representation other than those expressly contained herein, and it cannot
be modified, amended or extended except in a writing signed by you and a duly authorized member of the Board. This Agreement is
intended to bind and inure to the benefit of and be enforceable by you and the Company, and our respective successors, assigns,
heirs, executors and administrators, except that you may not assign any of your duties or rights hereunder without the express
written consent of the Company. Whenever possible, each provision of this Agreement will be interpreted in such manner as to be
effective and valid under applicable law, but if any provision of this Agreement is held to be invalid, illegal or unenforceable
in any respect under any applicable law or rule in any jurisdiction, such invalidity, illegality or unenforceability will
not affect any other provision or any other jurisdiction, but this Agreement will be reformed, construed and enforced as if such
invalid, illegal or unenforceable provisions had never been contained herein. This Agreement and the terms of your employment with
the Company shall be governed in all aspects by the laws of the State of California.

 

If you agree to the terms and conditions
set forth herein, please sign below.

 

	Best regards,	 
	 	 
	 	 
	/s/ Sean Bohen	 
	Sean Bohen, M.D., Ph.D.	 
	Chief Executive Officer	 
	 	 
	Accepted and agreed:	 
	 	 
	 	 
	/s/ Peter Kushner	 
	Peter Kushner	 
	 	 
	Date: November 13, 2020

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