Document:

Exhibit
10.3

 

SUBORDINATION
AND INTERCREDITOR AGREEMENT

 

This
Subordination and Intercreditor Agreement (the “Agreement”) is made as of November 1, 2021 by and between BroadOak
Fund V, L.P. ( “Creditor”) and COMERICA BANK (“Bank”).

 

Recitals

 

A. Interpace
Biosciences, Inc., a Delaware corporation, Interpace Diagnostics
Corporation, a Delaware corporation, Interpace Diagnostics, LLC, a
Delaware limited liability company and Interpace Pharma Solutions,
Inc., a Delaware corporation (jointly and severally, “Borrower”), has requested and/or
obtained certain loans or other credit accommodations from Bank which are or may be from time to time secured by assets and property
of Borrower, under that certain Loan and Security Agreement, dated as of October 13, 2021 (as amended, restated, modified,
supplemented, and/or replaced from time to time, the “Senior Loan Agreement”), between Borrower and
Bank.

 

B.
Creditor has extended loans or other credit accommodations to Borrower, and/or may extend loans or other credit accommodations to
Borrower from time to time, under that certain Loan and Security Agreement, dated as of October 29, 2021 (as amended, restated,
modified, supplemented, and/or replaced from time to time, the “Subordinated Loan Agreement”), between
Borrower and Creditor.

 

C.
In order to induce Bank to extend credit to Borrower and, at any time or from time to time, at Bank’s option, to make such
further loans, extensions of credit, or other accommodations to or for the account of Borrower, or to purchase or extend credit upon
any instrument or writing in respect of which Borrower may be liable in any capacity, or to grant such renewals or extension of any
such loan, extension of credit, purchase, or other accommodation as Bank may deem advisable, Creditor is willing to subordinate: (i)
all of Borrower’s indebtedness and obligations to Creditor, whether presently existing or arising in the future to all of
Borrower’s indebtedness and obligations to Bank; and (ii) all of Creditor’s security interests, if any to all of
Bank’s security interests in the Borrower’s property.

 

NOW,
THEREFORE, THE PARTIES AGREE AS FOLLOWS:

 

1. Definitions.
Capitalized terms not otherwise defined herein shall have the same meaning as in the Senior Loan Agreement. In addition, the
following capitalized terms have the meanings given below:

 

(a)
“Bank Services Debt” means obligations of Borrower to Bank or any affiliate of Bank in connection
with any products or services requested by Borrower and approved by Bank including, without limitation, ACH transactions (including
overdrafts), foreign exchange transactions and contracts, letters of credit, corporate credit cards and other treasury and cash
management products and services (including maintaining deposit or securities accounts), in all cases whether or not provided
pursuant to the Senior Loan Agreement.

 

(b)
“Collateral” means all of Borrower’s and any Guarantor’s rights, titles, property and
interests in, any and all property and assets, of whatever nature and kind and wherever situated, both present and future, together
with all proceeds (including, without limitation, proceeds of insurance) of or derived from any of the foregoing, and including
without limitation, Collateral as such term is defined in each of the Lender Documents, including, without limitation, all
properties and assets of Borrower or any Guarantor in which either Creditor or Bank may from time to time have a Lien.

 

(c)
“Creditor Default and Enforcement Notice” means written notice delivered by Creditor to Bank (i)
stating that an Event of Default has occurred and is continuing under the Subordinated Loan Documents and providing a detailed
description of such Event of Default(s), (ii) stating that Creditor intends to take one or more Enforcement Actions with respect to
Borrower and/or Collateral, and providing a detailed description of the specific Enforcement Actions Creditor proposes to take, and
(iii) that such notice is delivered to Bank at least 30 days prior to the date of any proposed Enforcement Action by
Creditor.

    	 	 	 

    	 

    

 

(d)
“Enforcement Action” means any action by Bank or Creditor, whether judicial or non-judicial, to (i)
exercise any remedy with respect to the Collateral or Borrower or any Guarantor, (ii) repossess, collect, accelerate, offset,
recoup, give notification to third parties (including, without limitation, account debtor notices) with respect to, sell, dispose
of, foreclose upon, give notice of sale, disposition, or foreclosure with respect to, or obtain legal, equitable or injunctive
relief with respect to any indebtedness owing from Borrower or any Guarantor or with respect to any Collateral, including any sale
or disposition after the occurrence of an Event of Default with the consent of or at the direction of Bank or Creditor, (iii)
exercise any put option, (iv) redeem any equity securities, or (v) join in the filing by a Bank or Creditor of an involuntary
bankruptcy or insolvency proceeding against Borrower or any Guarantor, provided, however, none of the following actions shall be
deemed to be an Enforcement Action: (i) the imposition of a default rate or late fee as permitted pursuant to the provisions of the
applicable loan documents, (ii) the cessation of lending pursuant to the provisions of the applicable loan documents, including upon
the occurrence of an event of default, (iii) filing and defending any proof of claim in any Insolvency Proceeding, (iv) the
customary operation of a lockbox and/or dominion of funds account, including application by Bank of collections therein to
outstanding Senior Debt, and (v) application of pledged cash collateral by Bank to Bank Services Debt or Hedging Services
Debt.

 

(e)
“Guarantor” means any party or parties that becomes a guarantor of any of the Senior Debt or the
Subordinated Debt.

 

(f)
“Hedging Services Debt” means obligations of Borrower or any Guarantor to Bank in connection with
any interest rate swap, forward rate, basis swap, cap or floor transaction requested by Borrower or any Guarantor and approved by
Bank.

 

(g)
“Insolvency Proceeding” means any case or proceeding commenced by or against any person or entity
under any provision of the United States Bankruptcy Code, as amended, or under any other bankruptcy or insolvency law, including
assignments for the benefit of creditors, formal or informal moratoria, compositions, extensions generally with its creditors, or
proceedings seeking reorganization, arrangement, the appointment of a receiver, interim receiver or receiver and manager, or other
relief.

 

(h)
“Lender Documents” means, collectively, the Senior Loan Documents and the Subordinated Loan
Documents.

 

(i)
“Lenders” means collectively, Bank and Creditor.

 

(j)
“Liens” shall mean all liens, mortgages, security interests, pledges, charges, assignments, title
retention agreements, leases, hypothecs, or other security or claims or encumbrances with respect to any assets or
property.

 

(k)
“Paid in Full” means, with respect to the Senior Debt or Subordinated Debt that: (i) all of such
Senior Debt or Subordinated Debt (other than contingent indemnification, gross-up and make-whole obligations as to which, in each
case, no claim has been asserted) have been irrevocably paid, performed, or discharged in full; (ii) no Person has any further right
to obtain any loans, letters of credit, bankers’ acceptances, or other extensions of credit under the documents relating to
such Senior Debt or Subordinated Debt; and (iii) any and all letters of credit, bankers’ acceptances or similar instruments
issued under such documents have been cancelled and returned (or backed by standby letters of credit or cash collateralized in each
case on terms and conditions satisfactory to Bank) in accordance with the terms of such documents.

 

(l)
“Permitted Payments” means (a) scheduled repayments of principal when due under the Subordinated
Loan Documents as in effect on the date hereof or amended in accordance with the terms hereof (but no prepayments, whether optional
or mandatory); (b) scheduled payments of accrued interest (whether payable in cash or in-kind) when due under the Subordinated Loan
Documents as in effect on the date hereof or as amended in accordance with the terms hereof (including as may accrue during any
Insolvency Proceeding of Borrower or any Guarantor); (c) all reimbursable expenses, costs and professional fees and expenses as and
when due under the Subordinated Loan Documents in an annual aggregate amount not to exceed One Hundred Fifty Thousand Dollars
($150,000); and (d) other payments consented to in writing by Bank.

 

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(m)
“Senior Debt” means all indebtedness, liabilities and other obligations (including, without
limitation, principal, premium (if any), interest, fees, charges, expenses, costs, professional fees and expenses, and reimbursement
obligations) of Borrower to Bank now existing or hereafter arising under or in connection with the Senior Loan Documents, Bank
Services Debt, and Hedging Services Debt, whether absolute or contingent, direct or indirect, joint or several, contemplated or
uncontemplated, secured or unsecured, together with all costs of collecting and enforcing such obligations (including reasonable
attorneys’ fees), including, without limitation, (i) all principal, (ii) all interest accruing in respect of such principal
amount under the Senior Loan Documents whether before or after the commencement by or against Borrower of any Insolvency Proceeding,
and (iii) such other amounts as may accrue or be incurred in respect of Obligations owing under the Senior Loan Documents before or
after default or workout or the commencement of any Insolvency Proceeding by or against Borrower (or, for purposes of the foregoing
clauses (ii) or (iii), which would have accrued but for such Insolvency Proceeding and, in each case, whether or not a claim for all
or any portion of such amounts is allowed or allowable in such Insolvency Proceeding).

 

(n)
“Senior Debt Cap” means Senior Debt which shall not exceed an aggregate principal amount (other
than in respect of Bank Services Debt and Hedging Services Debt) of Eight Million Two Hundred Fifty Thousand Dollars ($8,250,000);
provided that the Senior Debt Cap shall not limit that amount of interest, fees, charges, expenses, indemnification claims and
payments, and other like amounts payable to Bank pursuant to the Senior Loan Documents.

 

(o) “Senior
Loan Documents” means the Senior Loan Agreement and the other Loan Documents (as that term is defined in the Senior
Loan Agreement), all instruments and agreements respecting Bank Services Debt or Hedging Services Debt and all other documents, instruments
or agreements entered into in connection therewith or evidencing, guarantying, securing or otherwise documenting the whole or any part
of the Senior Debt as the same may from time to time be amended, modified, supplemented, extended, renewed, restated, replaced or refinanced
from time to time.

 

(p) “Subordinated
Debt” means all indebtedness, obligations and liabilities (including, without limitation, principal, premium (if any),
interest, fees, charges, expenses, costs, professional fees and expenses, and reimbursement obligations) now or hereafter owed by Borrower
to Creditor now existing or hereafter arising under or in connection with the Subordinated Loan Documents, whether absolute or contingent,
direct or indirect, joint or several, contemplated or uncontemplated, secured or unsecured, together with all costs of collecting and
enforcing such obligations (including attorneys’ fees) including but not limited to: (i) all principal, (ii) all interest accruing
in respect of such principal amount under the Subordinated Loan Documents whether before or after the commencement by or against Borrower
of any bankruptcy, reorganization or similar proceeding; (iii) all obligations or liabilities of Borrower in connection with the redemption
or repurchase of any warrant issued under the Subordinated Loan Agreement or in connection with any redemption or repurchase of any equity
securities issued or issuable upon exercise of the rights under any such warrant or upon conversion of or in exchange for such warrant
or any equity securities issued or issuable thereunder; (iv) all obligations or liabilities of Borrower with respect to any put rights,
put options, or dividends in favor of Creditor or under the Subordinated Loan Documents, and (v) such other amounts as may accrue or
be incurred in respect of obligations owing under the Subordinated Loan Documents before or after default or workout or the commencement
of any Insolvency Proceeding by or against Borrower (or, for purposes of the foregoing clauses (ii) or (v), which would have accrued
but for such Insolvency Proceeding and, in each case, whether or not a claim for all or any portion of such amounts is allowed or allowable
in such Insolvency Proceeding).

 

(q) “Subordinated
Debt Cap” means Subordinated Debt shall not exceed an aggregate principal amount of Nine Million Dollars ($9,000,000),
minus all payments of principal in respect of Subordinated Debt; provided that the Subordinated Debt Cap shall not limit the amount of
interest, fees, expenses, indemnification claims and payments, and other like amounts payable to Creditor pursuant to the Subordinated
Loan Documents, and the aggregate outstanding amount of obligations under clause (p)(iii) and (p)(iv) above shall not at any time exceed
Four Million Dollars ($4,000,000) and at all times shall be unsecured.

 

(r) “Subordinated
Loan Documents” means that certain Subordinated Loan Agreement, and all other documents, instruments or agreements
entered into in connection therewith or evidencing, guarantying, securing or otherwise documenting the whole or any part of the Subordinated
Debt, as the same may from time to time be amended, modified, supplemented, extended, renewed, restated, replaced or refinanced.

 

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2. Creditor
subordinates to Bank any Lien that Creditor may, from time to time, have in any Collateral. Notwithstanding any contrary priority established
by (i) the manner, timing or order of attachment or perfection of the Liens granted to Creditor and Bank, including the filing dates
of their respective financing statements, (ii) the recording dates of any other security perfection documents, or (iii) possession, or
control, of any of the Collateral, the Liens of Bank in the Collateral, shall at all times be prior and senior to the Liens of Creditor.
The relative priorities specified herein are absolute and unconditional and are expressly not conditioned upon the non-avoidability or
perfection of the Lien to which another Lien is subordinated. Each of the parties hereto consents to the debt and Liens held by the other
in accordance with the terms of this Agreement, provided, however, that, until the Senior Debt has been Paid in Full, the debt and Liens
of the Creditor shall at all times be subordinated to the Senior Debt and Liens of the Bank and that the Collateral encumbered by any
Liens in favor of the Creditor shall also be encumbered by Liens in favor of the Bank. Each Lender agrees, subject to the terms hereof,
that it will not (and hereby waives any right to), directly or indirectly, contest or support any person in contesting, in any proceeding
(including any Insolvency Proceeding), the priority, validity, or the enforceability of a Lien held by the other Lender in the Collateral,
provided, however, that, notwithstanding the foregoing, each Lender shall be entitled to enforce its rights under this Agreement against
the other Lender.

 

3. All
Subordinated Debt is subordinated in right of payment and priority to all Senior Debt.

 

4. Creditor
will not demand nor receive from Borrower or any Guarantor (and Borrower and any Guarantor will not pay to Creditor) all or any part
of the Subordinated Debt, by way of payment, prepayment, setoff, lawsuit or otherwise, nor will Creditor take any Enforcement Action
against any Collateral, Borrower, or any Guarantor, for so long as any portion of the Senior Debt remains outstanding or Bank has any
obligation to extend credit to any Borrower, provided, however, that Creditor may, subject to this Section 4 and Section 5 hereof, receive
Permitted Payments. Notwithstanding the foregoing, Creditor may take Enforcement Action after one hundred fifty (150) days has elapsed
(the “Standstill Period”) since the date on which Bank received a Creditor Default and Enforcement Notice.
In the event that during or after the Standstill Period Bank has commenced an Enforcement Action or an Insolvency Proceeding has been
commenced, then such Standstill Period shall be extended or revived indefinitely during the continuation of such proceedings and actions
until the Senior Debt is Paid in Full.

 

5. Notwithstanding
anything to the contrary herein, upon (i) the occurrence and during the continuance of an Event of Default (under and as defined in the
Senior Loan Agreement and (ii) written notice thereof to Creditor from Bank (a “Payment Blockage Notice”),
Creditor shall not take any Enforcement Action or otherwise exercise any remedy with respect to Borrower, or any Guarantor or Collateral,
nor receive any payment from Borrower or any Guarantor in respect of any Subordinated Debt during each period (each a “Payment
Blockage Period”) commencing on the date of delivery of the Payment Blockage Notice and ending on the earliest to occur
of the following events:

 

(a) such
Event of Default has been cured or has been waived by Bank in writing, in its sole and absolute discretion;

 

(b) one
hundred fifty (150) days have passed from the date of such Payment Blockage Notice; provided, however, that (i) if, prior to the expiration
of such one hundred fifty (150) day period, (A) Bank has commenced an Enforcement Action, or (B) an Insolvency Proceeding is commenced
by or against Borrower or Guarantor, the Payment Blockage Period shall be automatically extended during the continuance of such actions
or proceedings or (ii) subject to clause (i) above, if there is a payment default relating to the Senior Debt, then such period shall
be extended until Bank has confirmed in writing to Creditor that all past due payments (including accelerated payments) owed to Bank
have been paid in full in cash or the waiver of such default; or

 

(c) the
Senior Debt has been Paid in Full and all obligations of Bank to extend credit to Borrower has terminated.

 

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Immediately
after expiration of a Payment Blockage Period, Creditor may accept and Borrower may make all Permitted Payments due and owing to Creditor,
unless such payment would cause an Event of Default under the Senior Loan Documents. In no event shall Bank issue Payment Blockage Notices
during the term of this Agreement for defaults which do not involve a failure to make a payment of Senior Debt for more than one hundred
fifty (150) days in the aggregate for any consecutive period of three hundred sixty-five (365) days (provided that any Payment Blockage
Notices sent as a result of (i) an Event of Default resulting from a payment default under the Senior Loan Documents, or (ii) Creditor
delivering a Creditor Default and Enforcement Notice to Bank shall be excluded from such limitation); provided, however,
that the foregoing limitation shall not apply in the event that prior to the expiration of any Payment Blockage Period or Standstill
Period Bank has commenced an Enforcement Action or an Insolvency Proceeding is commenced, then such period shall be extended during the
continuation of such proceedings and actions until the Senior Debt is Paid in Full.

 

6. Notwithstanding
the imposition of any Standstill Period or Payment Blockage Period, Creditor may, during the existence and continuance of any Subordinated
Event of Default, and in accordance with the terms thereof, (a) take action for non-payment of the Subordinated Debt for the purposes
of obtaining a monetary judgment in respect thereof, provided that (i) no measure is taken to enforce any judgment granted in such action,
(ii) such action would not have the effect of providing Creditor the right to receive payment of the Subordinated Debt prior to the Senior
Debt being Paid in Full, and (iii) that such action shall not contest the priority set out in this Agreement or otherwise have the effect
of providing the Creditor Liens priority over the Bank Liens, (b) take action as required to preserve the validity, efficacy or priority
of the Subordinated Debt and the Creditor Liens, provided that such action shall not contest the priority set out in this Agreement or
otherwise have the effect of providing the Creditor Liens priority over the Bank Liens, (c) take action for conversion of any non-fixed
charge to a fixed charge to the extent applicable under the Creditor’s security, and (d) give notice of default, demand for payment
or acceleration of the Subordinated Debt or similar notices to Borrower.

 

7. Creditor
shall promptly deliver to Bank in the form received (except for endorsement or assignment by Creditor where required by Bank) for application
to the Senior Debt any payment, distribution, security or proceeds received by Creditor with respect to the Subordinated Debt other than
in accordance with this Agreement.

 

8. (a)
In the event of an Insolvency Proceeding of the Borrower, these provisions shall remain in full force and effect, and Bank’s claims
against Borrower and the estate of Borrower shall be Paid in Full before any payment is made to Creditor, and this Agreement shall be
considered to be a “subordination agreement” under Section 510 of the United States Bankruptcy Code, as amended, and all
references herein to Borrower shall apply to the trustee for the Borrower and any such Borrower as a debtor-in-possession.

 

(b) In
the event and during the continuation of any Insolvency Proceeding, the Creditor shall not object to or oppose any cash collateral order
approved by the Bank (or to which Bank does not object) or to the provision of any debtor-in-possession financing provided or approved
by Bank (“DIP Financing”), even if secured (with or without any pre-petition Senior Debt) by senior Liens on
the property of Borrower (and to the extent such debtor-in-possession financing Liens are senior to, or rank pari-passu with, the Lien
securing the pre-petition Senior Debt, the Creditor will subordinate the Liens securing the Subordinated Debt to such Liens securing
the DIP Financing and the pre-petition Senior Debt), provided (i) the interest rate, fees, advance rates and lending limits are commercially
reasonable under the circumstances, (ii) such order or financing is not inconsistent with this Agreement, (iii) Creditor otherwise retains
its Liens on the Collateral on substantially the same terms as in effect as of the date hereof, and (iv) the aggregate principal amount
of loans and letter of credit obligations that could be outstanding under any such DIP Financing, together with the outstanding principal
amount of the pre-petition Senior Debt that is outstanding (immediately after giving effect to any payment thereof with the proceeds
of any such DIP Financing), shall not exceed 115% of the cap on the aggregate principal amount of the Senior Debt set forth in the definition
of Senior Debt.

 

(c) The
Creditor may seek adequate protection of its interest in Collateral securing the Subordinated Debt in the form of replacement Liens on
post-petition collateral of the same type as the collateral securing the pre-petition Subordinated Debt so long as the Bank has been
granted replacement Liens on such collateral securing the pre-petition Senior Debt (but the failure to obtain adequate protection shall
not affect the agreements of the Creditor hereunder). The Creditor agrees that it shall not contest or support any other person contesting
any request by Senior Creditor for such Liens. Nor shall the Creditor oppose any request by the Bank for relief from the automatic stay
or any other stay in any Insolvency Proceeding, provided that if the stay is lifted with respect to the Senior Debt, then the Bank agrees
not to oppose a motion by the Creditor to lift the automatic stay to take any action permitted to be taken by the Creditor hereunder.

 

    	 	5	 

    	 

    

 

 

9. Until
such time as the Senior Debt is Paid in Full and Bank no longer has any obligation to extend credit to Borrower, Creditor irrevocably
appoints Bank as Creditor’s attorney in fact, and grants to Bank a power of attorney with full power of substitution, in the name
of Creditor or in the name of Bank, for the use and benefit of Bank, without notice to Creditor, to perform at Bank’s option the
following acts in any Insolvency Proceeding involving Borrower:

 

(a) to
file the appropriate claim or claims in respect of the Subordinated Debt on behalf of Creditor if Creditor does not do so prior to thirty
(30) days before the expiration of the time to file claims in such proceeding and if Bank elects, in its sole discretion, to file such
claim or claims; and

 

(b) To
accept or reject any plan of reorganization or arrangement on behalf of Creditor and to otherwise vote Creditor’s claims in respect
of any Subordinated Debt if Creditor does not do so prior to thirty (30) days before the expiration of the time to do so, in any manner
that Bank deems appropriate for the enforcement of its rights hereunder; provided that Creditor shall not accept or reject any plan of
reorganization or arrangement or otherwise vote its claims in respect of any Subordinated Debt, unless such plan either (i) results in
the Senior Debt being Paid in Full, or (ii) is agreed to by the Bank.

 

10. Until
such time as the Senior Debt is Paid in Full and Bank no longer has any obligation to extend credit to Borrower, Creditor agrees that
it will not object to or oppose (i) the sale of the Borrower, or any Guarantor or (ii) the sale or other disposition of any property
of the Borrower or any Guarantor, if, in each case, Bank has consented to such sale of the Borrower or any Guarantor or sale or disposition
of any property of the Borrower or any Guarantor, and whether or not such sale is conducted under Section 363 of the United States Bankruptcy
Code as amended. If requested by Bank, Creditor shall affirmatively consent to such sale or disposition and shall take all necessary
actions and execute such documents and instruments as Bank may reasonably request in connection with and to facilitate such sale or disposition
including, but not limited to, releasing any security interests held by Creditor in such property and filing any terminations of security
interests of Creditor in such property. If Creditor fails to take such actions within five (5) days of Bank’s request, Creditor
irrevocably appoints Bank as Creditor’s attorney in fact, and grants to Bank a power of attorney with full power of substitution,
in the name of Creditor or in the name of Bank, for the use and benefit of Bank, without notice to Creditor, to perform at Bank’s
option to take such actions. Furthermore, Creditor agrees to cooperate with Bank and to take all actions that Bank may reasonable require
to enable Bank to realize the full benefits of this Agreement.

 

11. Creditor
shall immediately affix a legend to the instruments evidencing the Subordinated Debt stating that the instruments are subject to the
terms of this Agreement or otherwise include a statement to that effect in the Subordinated Loan Agreement. No amendment of the Subordinated
Loan Documents shall directly or indirectly modify the provisions of this Agreement in any manner which might terminate or impair the
subordination of the Subordinated Debt or the subordination of the Liens that Creditor may have in any Collateral. Creditor acknowledges
and agrees that the provisions of the Subordinated Loan Agreement and any Subordinated Loan Documents may not be amended or modified
if the effect of such amendment or substitution is to: (a) increase any rate of cash interest or applicable cash interest rate margin
related to the Subordinated Debt other than an increase of not more than three percentage points (3.00%) from the rate or margin as in
effect on the date hereof, except in connection with the imposition of a default rate of interest in accordance with the terms of the
Subordinated Loan Documents as in effect on the date hereof and fluctuations in the base rate; (b) change the dates upon which payments
of principal or interest are due on the Subordinated Debt other than to extend any such dates; (c) increase the outstanding principal
amount of the loans or such other credit accommodations under the Subordinated Debt to a principal amount that would exceed the Subordinated
Debt Cap; (d) make the terms (other than changes in principal and/or interest payments to the extent expressly permitted under this section),
provisions covenants and/or events of default materially more restrictive on the Borrower than those in effect on the date of this Agreement
(other than modifications or additions to reflect conforming changes made with respect to the corresponding provisions contained in the
Senior Loan Documents, so long as any applicable set back or cushion is maintained) or (e) add collateral.

 

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12. This
Agreement shall remain effective until such time that the Senior Debt is Paid in Full and Bank no longer has any obligation to extend
credit to Borrower. If, at any time after the Senior Debt is Paid in Full any payments of the Senior Debt must be disgorged by Bank for
any reason (including, without limitation, the bankruptcy of Borrower or any Guarantor), this Agreement and the relative rights and priorities
set forth herein shall be reinstated as to all such disgorged payments as though such payments had not been made and Creditor shall immediately
pay over to Bank all payments received with respect to the Subordinated Debt to the extent that such payments would have been prohibited
hereunder. At any time and from time to time, without notice to Creditor, Bank may take such actions with respect to the Senior Debt
as Bank, in its sole discretion, may deem appropriate, including, without limitation, terminating advances to Borrower, increasing the
principal amount (not to exceed the Senior Debt Cap), extending the time of payment, renewing, compromising or otherwise amending the
terms of any documents affecting the Senior Debt and any Collateral securing the Senior Debt, and enforcing or failing to enforce any
rights against Borrower, Guarantor, or any other person. Notwithstanding anything to the contrary set forth herein, Bank acknowledges
and agrees that the provisions of the Senior Loan Agreement and any Senior Loan Documents may not be amended or modified if the effect
of such amendment or substitution is to increase any rate of cash interest or applicable cash interest rate margin related to the Senior
Debt other than an increase of not more than three percentage points (3.00%) from the rate or margin as in effect on the date hereof,
except in connection with the imposition of a default rate of interest in accordance with the terms of the Senior Loan Documents as in
effect on the date hereof and fluctuations in the base rate. No such action or inaction shall impair or otherwise affect Bank’s
rights hereunder. Creditor waives the benefits, if any, of Civil Code sections 2799, 2808, 2809, 2810, 2815, 2819, 2820, 2821, 2822,
2838, 2839, 2845, 2847, 2848, 2849, 2850, 2899 and 3433.

 

13. Until
the payment in full of Senior Debt, (i) the Bank shall have the sole and exclusive right to adjust and settle any claim under any insurance
policy covering the Collateral and to approve any award granted in any condemnation or similar proceeding (or any deed in lieu of condemnation)
affecting any Collateral, (ii) all proceeds of any such policy and any such award (or any payments with respect to a deed in lieu of
condemnation) shall be paid to Bank pursuant to the terms of the Senior Loan Documents and after the payment in full of Senior Indebtedness
has occurred, to Subordinated Creditor to the extent required under the Subordinated Loan Agreement, and (iii) if Creditor shall, at
any time, receive any proceeds of any such insurance policy or any such award or payment in contravention of this Agreement, it shall
pay such proceeds over to Bank.

 

14.
(a) Subject to the limitations set forth herein, after the occurrence of any of the following: (i) acceleration by Bank of the
Senior Debt in accordance with the terms of the Senior Loan Documents or (ii) an Insolvency Proceeding has commenced (each a
“Purchase Trigger Event”), Creditor shall have the option (but not the obligation) to purchase all (but
not less than all) of the Senior Debt (including any DIP Financing provided by Bank) (the “Purchase
Option”); provided that such Purchase Option shall expire if Creditor fails to deliver a written notice exercising the
Purchase Option pursuant to this Agreement (the “Purchase Notice”) to Bank within twenty (20) days
following the occurrence of a Purchase Trigger Event. The Purchase Notice, once delivered to Bank, shall be irrevocable. After the
expiration of such twenty (20) day period (the “Notice Period”), Creditor shall not be entitled to send a
Purchase Notice until the occurrence of a subsequent Purchase Trigger Event.

 

(b) Until
(i) the delivery of a timely Purchase Notice within the Notice Period, (ii) after expiration of the Notice Period if Creditor has failed
to deliver a Purchase Notice, and (iii) after Creditor has delivered a Purchase Notice within the Notice Period, but fails to consummate
the purchase of the Senior Debt according to the terms hereof on or before the Purchase Date (as defined below), Bank shall be entitled
to take an Enforcement Action. During the period commencing on the date a Purchase Notice is properly received by Bank and ending on
the Purchase Date, Bank shall not take an Enforcement Action without the consent of Creditor (such consent not to be unreasonably withheld
or delayed), except as Bank deems necessary, in the exercise of its good faith credit judgment, to protect and preserve the Senior Debt
or Collateral.

 

(c) On
the date (the “Purchase Date”) specified in the Purchase Notice (which shall not be less than fifteen (15)
business days, nor more than twenty (20) business days, after the receipt by Bank of the Purchase Notice), subject to any required approval
of any court or other governmental authority, Bank shall sell to Creditor, and Creditor shall purchase from Bank, without recourse, representation
or warranty, the Senior Debt and assume all financing commitments and other duties, liabilities, and obligations of Bank under the Senior
Loan Documents. Such purchase and sale shall be made pursuant to Bank’s standard sale and assignment agreement, but without recourse
and without representation or warranty by Bank of any kind whatsoever, except that Bank shall represent and warrant: (i) the amount of
the Senior Debt being purchased from Bank; (ii) that Bank owns the Senior Debt free and clear of any liens created by Bank; and (iii)
Bank has the right to assign the Senior Debt; provided, however, that Bank shall retain its rights with respect to the indemnification
obligations of Borrower under the Senior Loan Documents for all claims accrued or arising in respect of periods prior to the consummation
of the purchase hereunder. Creditor shall have, and shall represent that it has, conducted, and that it shall be responsible for, its
own independent due diligence necessary to evaluate the Senior Loan Documents and the Senior Debt, and such other due diligence, as it
deems necessary or appropriate to complete the purchase of the Senior Debt.

 

    	 	7	 

    	 

    

 

(d) On
the Purchase Date, Creditor shall:

 

(i) as
the purchase price (the “Purchase Price”), pay to Bank, in immediately available funds, an amount equal to
all outstanding Senior Debt as of the Purchase Date, at par, including, without limitation, principal (including principal above the
Senior Debt Cap), end-of-term payments, prepayment premiums, break-funding or similar costs, interest, fees, costs and expenses (including,
without limit, any attorneys’ fees and costs), and other obligations, liabilities or charges that accrue in respect of the Senior
Debt);

 

(ii) furnish
cash collateral (“Cash Collateral”) to Bank that is satisfactory to Bank (or make such other accommodations
as are reasonably agreed between Bank and Creditor with respect to such obligations): (A) in an amount equal to one hundred fifteen percent
(115.0%) of the face amount of all letters of credit issued by Bank upon the application of and/or for the account of Borrower or any
Guarantor, plus all interest, reasonable fees, and costs due or to become due in connection therewith (as estimated by Bank in its good
faith business judgment), and (B) in an amount equal to Bank’s estimate (in its good faith business judgment) of the amount necessary
to cover any credit exposure in respect of all treasury or cash management, ACH transactions or other bank services provided by it to
Borrower or any Guarantor and any other contingent obligations (all of the foregoing in clause (A) and clause (B) being “Reimbursement
Obligations”), to fully cash collateralize and secure such Reimbursement Obligations; and

 

(iii) remit
the Purchase Price and Cash Collateral by wire transfer in immediately available funds to such bank account as Bank may specify.

 

(e) Creditor
shall agree to pay or reimburse Bank for any loss, cost, damage or expense (including, without limitation, reasonable attorneys’
fees and legal expenses) in connection with: any commissions, fees, costs or expenses related to any issued and outstanding letters of
credit as described above and any checks or other payments provisionally credited to Bank and/or as to which Bank has not yet received
final payment.

 

(f) If
Creditor’s purchase of the Senior Debt hereunder fails to be consummated by the Purchase Date for any reason other than a breach
by Bank of its obligations under this Purchase Option pursuant to this Section 13 or the purchase documents, then, (i) this Purchase
Option shall terminate and be of no further force and effect, and Bank shall have no further obligation to Creditor with respect to the
Purchase Option, and (ii) Bank may take Enforcement Action with respect to the Senior Debt and the Collateral and take such further actions
as it deems appropriate in its sole discretion in accordance with the Senior Loan Documents and this Agreement, and shall retain all
rights and claims against Creditor resulting from such failure by Creditor to consummate the purchase of the Senior Debt.

 

(g) Creditor
shall indemnify, defend and hold Bank and its officers, directors, shareholders, affiliates, agents, partners, members and employees
(each an “Indemnitee”) harmless from and against any liability, claim, cost, loss, judgment, damage or expense
(including, without limitation, reasonable attorney fees and expenses) that any Indemnitee incurs or suffers as a result of or arising
out of (i) Creditor’s exercise of the Purchase Option; (ii) any action taken by Creditor with respect to the Senior Debt following
the consummation of the purchase of the Senior Debt hereunder; or (iii) the breach of any of Creditor’s representations, warranties,
covenants or agreements in this Agreement or the purchase documents, in each case, except to the extent such liability claim, cost, loss,
judgment, damage or expense is the result of the willful misconduct or gross negligence of such Indemnitee, as determined by a final
non-appealable ruling by a court of competent jurisdiction or other tribunal.

 

(h) All
Senior Debt in excess of the Senior Debt Cap shall continue to be secured by the Collateral in accordance with the terms of the Senior
Loan Documents, and Bank shall retain all rights to receive payments (and to exercise its rights and remedies) in respect thereof, but
only after the payment in full in cash of the Subordinated Debt.

 

    	 	8	 

    	 

    

 

(i) Borrower
irrevocably consents to the existence of this Purchase Option and to any assignment effected pursuant thereto, and hereby agrees that
no further consent from Borrower or any Guarantor or any other obligor shall be required. Furthermore, Borrower agrees to indemnify,
release and hold Bank harmless from and against any and all liabilities, claims, costs, losses, judgments, damages or expenses (including,
without limitation, reasonable attorney fees and expenses) incurred or suffered in connection with or as a result of any assignment or
sale of the Senior Debt and/or any actions taken by Bank after exercise of the Purchase Option.

 

(j) Upon
the consummation of a purchase and sale pursuant to the Purchase Option, Creditor (and not Bank) will thereafter be obligated pursuant
to the terms of the Senior Loan Documents and responsible for the discharge and performance of all of the duties, responsibilities and
obligations of Bank under the Senior Loan Documents, and Bank will thereafter be released from and discharged of its duties, responsibilities
and obligations under or in connection with the Senior Debt and Senior Loan Documents.

 

15. This
Agreement shall bind any successors or assignees of Creditor and shall benefit any successors or assigns of Bank, provided, however,
Creditor agrees that, prior and as conditions precedent to Creditor assigning all or any portion of the Subordinated Debt: (a) Creditor
shall give Bank prior written notice of such assignment, and (b) such successor or assignee, as applicable, shall execute a written agreement
whereby such successor or assignee expressly agrees to assume and be bound by all terms and conditions of this Agreement with respect
to Creditor. This Agreement is solely for the benefit of Creditor and Bank and not for the benefit of Borrower or any other party. Creditor
further agrees that if Borrower is in the process of refinancing a portion of the Senior Debt with a new lender, and if Bank makes a
request of Creditor, Creditor shall agree to enter into a new subordination agreement with the new lender on substantially the terms
and conditions of this Agreement.

 

16. This
Agreement may be executed in any number of counterparts and by different parties on separate counterparts, each of which, when executed
and delivered, shall be deemed to be an original, and all of which, when taken together, shall constitute but one and the same Agreement.
Delivery of an executed counterpart of this Agreement by facsimile, emailed portable document format (“pdf”), or tagged image
file format (“tiff”) or any other electronic means that reproduces an image of the actual executed signature of an authorized
signer of such party shall be effective as delivery of an original executed counterpart of this certificate, and shall be equally as
effective as delivery of a manually executed counterpart of this Agreement. Any party delivering an executed counterpart of this Agreement
by facsimile, emailed portable document format (“pdf”), or tagged image file format (“tiff”) or any other electronic
means that reproduces an image of the actual executed signature of an authorized signer of such party, also shall deliver a manually
executed counterpart of this Agreement but the failure to deliver a manually executed counterpart shall not affect the validity, enforceability,
and binding effect of this Agreement.

 

17. Unless
otherwise provided in this Agreement, all notices or demands by any party relating to this Agreement or any other agreement entered into
in connection herewith shall be in writing and shall be personally delivered or sent by a recognized overnight delivery service, certified
mail, postage prepaid, return receipt requested, or by facsimile to Bank, Creditor, or Borrower, as the case may be, at the address set
forth below each party in its respective signature block. The parties hereto may change the address at which they are to receive notices
hereunder, by notice in writing in the foregoing manner given to the other parties.

 

    	 	9	 

    	 

    

 

18. THE
PARTIES HEREBY AGREE THAT THIS AGREEMENT AND ALL OTHER LOAN DOCUMENTS, INSTRUMENTS AND AGREEMENTS RELATED TO THIS AGREEMENT SHALL BE
GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF CALIFORNIA, WITHOUT REGARD TO ITS CONFLICTS OF LAW PROVISIONS.
CREDITOR, BORROWER AND BANK EACH HEREBY IRREVOCABLY AND UNCONDITIONALLY (I) CONSENTS AND SUBMITS TO THE SOLE AND EXCLUSIVE JURISDICTION
OF ANY STATE OR FEDERAL COURT LOCATED WITHIN THE STATE OF CALIFORNIA, AND ANY APPELLATE COURT THEREOF, (II) AGREES THAT ALL ACTIONS AND
PROCEEDINGS BASED UPON, ARISING OUT OF, RELATING TO OR OTHERWISE CONCERNING THIS AGREEMENT OR ANY OTHER DOCUMENT, INSTRUMENT OR AGREEMENT
RELATED TO THIS AGREEMENT, INCLUDING ALL CLAIMS FOR RECOGNITION OR ENFORCEMENT OF ANY JUDGMENT, SHALL SOLELY AND EXCLUSIVELY BE BROUGHT,
HEARD, AND DETERMINED (LITIGATED) IN SUCH COURTS, (III) ACCEPTS FOR ITSELF AND IN CONNECTION WITH ITS PROPERTIES, THE SOLE AND EXCLUSIVE
JURISDICTION OF THE AFORESAID COURTS, (IV) WAIVES ANY OBJECTION, INCLUDING ANY OBJECTION TO THE LAYING OF VENUE OR BASED UPON THE GROUNDS
OF FORUM NON CONVENIENS, THAT IT MAY NOW OR HEREAFTER HAVE TO BRINGING OR MAINTAINING ANY SUCH ACTION OR PROCEEDING IN SUCH JURISDICTION,
AND (V) AGREES TO BE BOUND BY ANY JUDGMENT RENDERED THEREBY IN CONNECTION WITH THIS AGREEMENT, OR ANY SUCH OTHER DOCUMENT, INSTRUMENT
OR AGREEMENT. NOTHING HEREIN SHALL LIMIT THE RIGHT OF BANK TO BRING ANY ACTION OR PROCEEDING AGAINST, CREDITOR OR ITS PROPERTIES OR BORROWER
OR ITS PROPERTIES IN THE COURTS OF ANY OTHER JURISDICTION IN CONNECTION WITH THE ENFORCEMENT OF ANY LIENS OR SECURITY INTERESTS IN FAVOR
OF BANK ON ANY OF CREDITOR’S PROPERTIES OR ASSETS OR BORROWER’S PROPERTIES OR ASSETS.

 

19. JURY
TRIAL WAIVER. THE UNDERSIGNED ACKNOWLEDGE THAT THE RIGHT TO TRIAL BY JURY IS A CONSTITUTIONAL ONE, BUT THAT IT MAY BE WAIVED UNDER
CERTAIN CIRCUMSTANCES. TO THE EXTENT PERMITTED BY LAW, EACH PARTY, AFTER CONSULTING (OR HAVING HAD THE OPPORTUNITY TO CONSULT) WITH COUNSEL
OF ITS, HIS OR HER CHOICE, KNOWINGLY AND VOLUNTARILY, AND FOR THE MUTUAL BENEFIT OF ALL PARTIES, WAIVES ANY RIGHT TO TRIAL BY JURY IN
THE EVENT OF LITIGATION ARISING OUT OF OR RELATED TO THIS AGREEMENT OR ANY OTHER DOCUMENT, INSTRUMENT OR AGREEMENT BETWEEN THE UNDERSIGNED
PARTIES.

 

20. JUDICIAL
REFERENCE PROVISION.

 

(i) In
the event the Jury Trial Waiver set forth above is not enforceable, the parties elect to proceed under this Judicial Reference Provision.

 

(ii) With
the exception of the items specified in Section 14(c), below, any controversy, dispute or claim (each, a “Claim”) between
the parties arising out of or relating to this Agreement or any other document, instrument or agreement between the undersigned parties
(collectively in this Section, the “Loan Documents”), will be resolved by a reference proceeding in California in accordance
with the provisions of Sections 638 et seq. of the California Code of Civil Procedure (“CCP”), or their successor sections,
which shall constitute the exclusive remedy for the resolution of any Claim, including whether the Claim is subject to the reference
proceeding. Except as otherwise provided in the Loan Documents, venue for the reference proceeding will be in the state or federal court
in the county or district where the real property involved in the action, if any, is located or in the state or federal court in the
county or district where venue is otherwise appropriate under applicable law (the “Court”).

 

(iii) The
matters that shall not be subject to a reference are the following: (i) foreclosure of any security interests in real or personal property,
(ii) exercise of self-help remedies (including, without limitation, set-off), (iii) appointment of a receiver and (iv) temporary, provisional
or ancillary remedies (including, without limitation, writs of attachment, writs of possession, temporary restraining orders or preliminary
injunctions). This Judicial Reference Provision does not limit the right of any party to exercise or oppose any of the rights and remedies
described in clauses (i) and (ii) or to seek or oppose from a court of competent jurisdiction any of the items described in clauses (iii)
and (iv). The exercise of, or opposition to, any of those items does not waive the right of any party to a reference proceeding pursuant
to this Judicial Reference Provision as provided herein.

 

(iv) The
referee shall be a retired judge or justice selected by mutual written agreement of the parties. If the parties do not agree within ten
(10) days of a written request to do so by any party, then, upon request of any party, the referee shall be selected by the Presiding
Judge of the Court (or his or her representative). A request for appointment of a referee may be heard on an ex parte or expedited basis,
and the parties agree that irreparable harm would result if ex parte relief is not granted. Pursuant to CCP § 170.6, each party
shall have one peremptory challenge to the referee selected by the Presiding Judge of the Court (or his or her representative).

 

    	 	10	 

    	 

    

 

(v) The
parties agree that time is of the essence in conducting the reference proceedings. Accordingly, the referee shall be requested, subject
to change in the time periods specified herein for good cause shown, to (i) set the matter for a status and trial-setting conference
within fifteen (15) days after the date of selection of the referee, (ii) if practicable, try all issues of law or fact within one hundred
twenty (120) days after the date of the conference and (iii) report a statement of decision within twenty (20) days after the matter
has been submitted for decision.

 

(vi) The
referee will have power to expand or limit the amount and duration of discovery. The referee may set or extend discovery deadlines or
cutoffs for good cause, including a party’s failure to provide requested discovery for any reason whatsoever. Unless otherwise
ordered based upon good cause shown, no party shall be entitled to “priority” in conducting discovery, depositions may be
taken by either party upon seven (7) days written notice, and all other discovery shall be responded to within fifteen (15) days after
service. All disputes relating to discovery which cannot be resolved by the parties shall be submitted to the referee whose decision
shall be final and binding.

 

(vii) Except
as expressly set forth herein, the referee shall determine the manner in which the reference proceeding is conducted including the time
and place of hearings, the order of presentation of evidence, and all other questions that arise with respect to the course of the reference
proceeding. All proceedings and hearings conducted before the referee, except for trial, shall be conducted without a court reporter,
except that when any party so requests, a court reporter will be used at any hearing conducted before the referee, and the referee will
be provided a courtesy copy of the transcript. The party making such a request shall have the obligation to arrange for and pay the court
reporter. Subject to the referee’s power to award costs to the prevailing party, the parties will equally share the cost of the
referee and the court reporter at trial.

 

(viii) The
referee shall be required to determine all issues in accordance with existing case law and the statutory laws of the State of California.
The rules of evidence applicable to proceedings at law in the State of California will be applicable to the reference proceeding. The
referee shall be empowered to enter equitable as well as legal relief, enter equitable orders that will be binding on the parties and
rule on any motion which would be authorized in a court proceeding, including without limitation motions for summary judgment or summary
adjudication. The referee shall issue a decision at the close of the reference proceeding which disposes of all claims of the parties
that are the subject of the reference. Pursuant to CCP § 644, such decision shall be entered by the Court as a judgment or an order
in the same manner as if the action had been tried by the Court and any such decision will be final, binding and conclusive. The parties
reserve the right to appeal from the final judgment or order or from any appealable decision or order entered by the referee. The parties
reserve the right to findings of fact, conclusions of laws, a written statement of decision, and the right to move for a new trial or
a different judgment, which new trial, if granted, is also to be a reference proceeding under this provision.

 

(ix) If
the enabling legislation which provides for appointment of a referee is repealed (and no successor statute is enacted), any dispute between
the parties that would otherwise be determined by reference procedure will be resolved and determined by arbitration. The arbitration
will be conducted by a retired judge or justice, in accordance with the California Arbitration Act §1280 through §1294.2 of
the CCP as amended from time to time. The limitations with respect to discovery set forth above shall apply to any such arbitration proceeding.

 

(x) THE
PARTIES RECOGNIZE AND AGREE THAT ALL CONTROVERSIES, DISPUTES AND CLAIMS RESOLVED UNDER THIS JUDICIAL REFERENCE PROVISION WILL BE DECIDED
BY A REFEREE AND NOT BY A JURY. AFTER CONSULTING (OR HAVING HAD THE OPPORTUNITY TO CONSULT) WITH COUNSEL OF ITS, HIS OR HER OWN CHOICE,
EACH PARTY KNOWINGLY AND VOLUNTARILY, AND FOR THE MUTUAL BENEFIT OF ALL PARTIES, AGREES THAT THIS JUDICIAL REFERENCE PROVISION WILL APPLY
TO ANY CONTROVERSY, DISPUTE OR CLAIM BETWEEN OR AMONG THEM ARISING OUT OF OR IN ANY WAY RELATED TO, THIS AGREEMENT OR THE OTHER LOAN
DOCUMENTS.

 

21. In
the event of any legal action to enforce the rights of a party under this Agreement, the party prevailing in such action shall be entitled,
in addition to such other relief as may be granted, all reasonable costs and expenses, including reasonable attorneys’ fees, incurred
in such action.

 

22.
This Agreement represents the entire agreement with respect to the subject matter hereof, and supersedes all prior negotiations,
agreements and commitments. Creditor hereby assumes responsibility of keeping itself informed of the financial condition of
Borrower, and any and all Guarantors of the Senior Debt and of all other circumstances bearing upon the risk of nonpayment of the
Senior Debt or the Subordinated Debt that diligent inquiry would reveal, and Creditor hereby agrees that Bank shall not have any
duty to advise Creditor of information known to Bank regarding such condition. Creditor is not relying on any representations by
Bank or Borrower in entering into this Agreement. This Agreement may be amended only by written instrument signed by Creditors and
Bank. 

 

[Remainder
of page left intentionally blank; Signature pages follow.]

 

    	 	11	 

    	 

    

 

IN
WITNESS WHEREOF, the undersigned have executed this Agreement as of the date first above written.

 

	 	“Bank”
	 	 
	 	COMERICA
    BANK
	 	 	 
	 	By:	 
	 	Name:	Shane
    Merkord
	 	Title:	Vice
    President

 

	 	Comerica Bank
	 	M/C 7578
	 	39200 Six Mile Rd.
	 	Livonia, MI 48152
	 	Attn: National Documentation Services
	 	 
	 	With a copy to:
	 	Comerica Bank
	 	300 W. 6th Street, Suite 1950
	 	Austin, TX 78701
	 	Attn: Shane Merkord
	 	Email: sgmerkord@comerica.com

 

	 	“Creditor”
	 	 
	 	BROADOAK
    FUND V, L.P.
	 	 	 
	 	By:	 
	 	Name:	William
    Snider
	 	Title:	Manager

 

	 	BroadOak Fund V, L.P.
	 	4800 Montgomery Lane, Suite 230
	 	Bethesda, MD 20814
	 	Attention: Manager
	 	Email: compliance@broadoak.com

 

[SIGNATURES
CONTINUED ON NEXT PAGE]

 

[Signature
Page to Subordination and Intercreditor Agreement (18083892)]

 

    	 	 	 

    	 

    

 

The
undersigned approves of the terms of this Agreement.

 

	INTERPACE
    BIOSCIENCES, INC.	 
	 	 	 
	By:	 	 
	Name:	Thomas
    W. Burnell	 
	Title:	Chief
    Executive Officer	 
	 	 	 
	INTERPACE
    DIAGNOSTICS CORPORATION	 
	 	 	 
	By:	 	 
	Name:	Thomas
    W. Burnell	 
	Title:	Chief
    Executive Officer	 
	 	 	 
	INTERPACE
    DIAGNOSTICS, LLC	 
	 	 	 
	By:	 	 
	Name:	Thomas
    W. Burnell	 
	Title:	Chief
    Executive Officer	 
	 	 	 
	INTERPACE
    PHARMA SOLUTIONS, INC.	 
	 	 	 
	By:	 	 
	Name:	Thomas
    W. Burnell	 
	Title:	Chief
    Executive Officer	 

 

c/o
Interpace Biosciences, Inc.

Morris
Corporate Center 1, Building C

300
Interpace Parkway

Parsippany,
NJ 07054

Attn:
Thomas Freeburg, CFO

Email:
tfreeburg@interpace.com

 

[Signature
Page to Subordination and Intercreditor Agreement (18083892)]EX-4.1

 Exhibit 4.1 

Execution Version 

FIRST SUPPLEMENTAL INDENTURE 

First Supplemental Indenture (this “Supplemental Indenture”), dated as of November 1, 2021, among each of the entities
listed on Exhibit A attached hereto (collectively, the “Guaranteeing Subsidiaries,” and each a “Guaranteeing Subsidiary”), each a subsidiary of Civitas Resources, Inc. (f/k/a Bonanza Creek Energy, Inc.), a
Delaware corporation (the “Company”), the Company, the other Guarantors (as defined in the Indenture referred to herein) and Computershare Trust Company, N.A., as successor trustee under the Indenture referred to below (the
“Trustee”). 
 W I T N E S S E T H 

WHEREAS, the Company has heretofore executed and delivered to the Trustee an indenture (the “Indenture”), dated as of
October 13, 2021, providing for the issuance of 5.000% Senior Notes due October 15, 2026 (the “Notes”); 

WHEREAS, the Indenture provides that under certain circumstances a Guaranteeing Subsidiary shall execute and deliver to the Trustee a
supplemental indenture pursuant to which such Guaranteeing Subsidiary shall unconditionally Guarantee all of the Company’s Obligations under the Notes and the Indenture on the terms and conditions set forth herein (the “Note
Guarantee”); and 
 WHEREAS, pursuant to Section 9.01 of the Indenture, the Trustee is authorized to execute and deliver this
Supplemental Indenture without the consent of Holders of the Notes. 
 NOW, THEREFORE, in consideration of the foregoing and for other good
and valuable consideration, the receipt of which is hereby acknowledged, the Guaranteeing Subsidiaries, the other Guarantors, the Company and the Trustee mutually covenant and agree for the equal and ratable benefit of the Holders of the Notes as
follows: 
 1. CAPITALIZED TERMS. Capitalized terms used herein without definition shall have the meanings assigned to them in the Indenture.

 2. AGREEMENT TO GUARANTEE. Each Guaranteeing Subsidiary hereby agrees to provide an unconditional Guarantee on the terms and subject to
the conditions set forth in the Note Guarantee and in the Indenture including but not limited to Article 10 thereof. 
 3. NO RECOURSE
AGAINST OTHERS. No director, manager, officer, member, employee, incorporator or unitholder or other owner of Capital Stock of the Company or any Guarantor, as such, will have any liability for any obligations of the Company or the Guarantors under
the Notes, the Indenture or the Note Guarantees or for any claim based on, in respect of, or by reason of, such obligations or their creation. Each Holder of Notes by accepting a Note waives and releases all such liability. The waiver and release
are part of the consideration for issuance of the Notes. 
 4. NEW YORK LAW TO GOVERN. THE LAW OF THE STATE OF NEW YORK SHALL GOVERN AND BE
USED TO CONSTRUE THIS SUPPLEMENTAL INDENTURE. 

 5. COUNTERPARTS. The parties may sign any number of copies of this Supplemental Indenture,
and each party hereto may sign any number of separate copies of this Indenture. Each signed copy shall be an original, but all of them together represent the same agreement. The exchange of copies of this Indenture and of signature pages by
facsimile or PDF transmission shall constitute effective execution and delivery of this Indenture as to the parties hereto and may be used in lieu of the original Indenture for all purposes. Signatures of the parties hereto transmitted by facsimile
or PDF shall be deemed to be their original signatures for all purposes. 
 6. EFFECT OF HEADINGS. The headings of the Sections of this
Supplemental Indenture have been inserted for convenience of reference only, are not to be considered a part of this Supplemental Indenture and will in no way modify or restrict any of the terms or provisions hereof. 

7. THE TRUSTEE. The Trustee shall not be responsible in any manner whatsoever for or in respect of the validity or sufficiency of this
Supplemental Indenture or for or in respect of the recitals contained herein, all of which recitals are made solely by the Guaranteeing Subsidiaries, the other Guarantors and the Company. 

  
 2 

 IN WITNESS WHEREOF, the parties hereto have caused this Supplemental Indenture to be duly
executed and attested, all as of the date first above written. 
  

			
	COMPANY: 
	
	CIVITAS RESOURCES, INC.,
		
	By:	 	 /s/ Cyrus D. Marter IV

		 	Name: Cyrus D. Marter IV
		 	Title:   General Counsel and Secretary

  
 [Signature page to
First Supplemental Indenture] 

 
	
	GUARANTEEING SUBSIDIARIES:
	
	EXTRACTION OIL & GAS, INC.
	RAPTOR CONDOR MERGER SUB 2, LLC
	CRESTONE PEAK RESOURCES GP INC.
	CRESTONE PEAK RESOURCES LP
	CRESTONE PEAK RESOURCES LLC
	CRESTONE PEAK RESOURCES HOLDINGS LLC
	CRESTONE PEAK RESOURCES OPERATING LLC
	CRESTONE PEAK RESOURCES MIDSTREAM LLC
	CRESTONE PEAK RESOURCES ACQUISITION COMPANY I LLC
	COLLEGIATE HOLDINGS LLC
	CRESTONE PEAK RESOURCES WATKINS MIDSTREAM LLC
	 CRESTONE PEAK RESOURCES WATKINS HOLDINGS LLC 

8 NORTH, LLC 
 7N, LLC

	TABLE MOUNTAIN RESOURCES, LLC
	NORTHWEST CORRIDOR HOLDINGS, LLC
	XTR MIDSTREAM, LLC
	EXTRACTION FINANCE CORP.
	AXIS EXPLORATION, LLC
	XOG SERVICES, LLC
	MOUNTAINTOP MINERALS, LLC

  

			
	By:	 	 /s/ Cyrus D. Marter IV

		 	Name: Cyrus D. Marter IV
		 	Title:   President and Secretary

  
 [Signature page to
First Supplemental Indenture] 

 
			
	EXISTING GUARANTORS:
	
	BONANZA CREEK ENERGY OPERATING COMPANY, LLC
	
	By: Civitas Resources, Inc., as sole member
		
	By:	 	 /s/ Cyrus D. Marter IV

		 	Name: Cyrus D. Marter IV
		 	Title:   General Counsel and Secretary
	
	HIGHPOINT RESOURCES CORPORATION
	
	By: Civitas Resources, Inc., as sole stockholder
		
	By:	 	 /s/ Cyrus D. Marter IV

		 	Name: Cyrus D. Marter IV
		 	Title:   General Counsel and Secretary
	
	ROCKY MOUNTAIN INFRASTRUCTURE, LLC
	HOLMES EASTERN COMPANY, LLC
	
	By: Bonanza Creek Energy Operating Company, as sole member
	
	By: Civitas Resources, Inc., as sole member
		
	By:	 	 /s/ Cyrus D. Marter IV

		 	Name: Cyrus D. Marter IV
		 	Title:   General Counsel and Secretary

 [Signature page to First Supplemental Indenture] 

 
			
	HIGHPOINT OPERATING CORPORATION
	
	By: Highpoint Resources Corporation, as sole stockholder
	
	By: Civitas Resources, Inc., as sole stockholder
		
	By:	 	 /s/ Cyrus D. Marter IV

		 	Name: Cyrus D. Marter IV
		 	Title:   General Counsel and Secretary
	
	FIFTH POCKET PRODUCTION, LLC
	
	By: Highpoint Operating Corporation, as sole member
	
	By: Highpoint Resources Corporation, as sole stockholder
	
	By: Civitas Resources, Inc., as sole stockholder
		
	By:	 	 /s/ Cyrus D. Marter IV

		 	Name: Cyrus D. Marter IV
		 	Title:   General Counsel and Secretary

 [Signature page to First Supplemental Indenture] 

 
			
	COMPUTERSHARE TRUST COMPANY, N.A., as Trustee
		
	By:	 	 /s/ Karla D. Sjostrom

		 	Name: Karla D. Sjostrom
		 	Title:   Vice President

 [Signature page to First Supplemental Indenture] 

 EXHIBIT A 

Additional Guarantors 
  

	1.	 Crestone Peak Resources GP Inc., a Delaware corporation 

	2.	 Crestone Peak Resources LP, a Delaware limited partnership 

	3.	 Crestone Peak Resources LLC, a Delaware limited liability company 

	4.	 Crestone Peak Resources Holdings LLC, a Delaware limited liability company 

	5.	 Crestone Peak Resources Operating LLC, a Delaware limited liability company 

	6.	 Crestone Peak Resources Midstream LLC, a Delaware limited liability company 

	7.	 Crestone Peak Resources Acquisition Company I LLC, a Delaware limited liability company 

	8.	 Collegiate Holdings LLC, a Delaware limited liability company 

	9.	 Crestone Peak Resources Watkins Midstream LLC, a Delaware limited liability company 

	10.	 Crestone Peak Resources Watkins Holdings LLC, a Delaware limited liability company 

	11.	 8 North, LLC, a Delaware limited liability company 

	12.	 7N, LLC, a Delaware limited liability company 

	13.	 Table Mountain Resources, LLC, a Delaware limited liability company 

	14.	 Northwest Corridor Holdings, LLC, a Delaware limited liability company 

	15.	 XTR Midstream, LLC, a Delaware limited liability company 

	16.	 Extraction Finance Corp., a Delaware corporation 

	17.	 Axis Exploration, LLC, a Delaware limited liability company 

	18.	 XOG Services, LLC, a Delaware limited liability company 

	19.	 Mountaintop Minerals, LLC, a Delaware limited liability company 

	20.	 Extraction Oil & Gas, Inc., a Delaware corporation 

	21.	 Raptor Condor Merger Sub 2, LLC, a Delaware limited liability company 

[Exhibit A to First Supplemental Indenture - Additional Guarantors]

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