Document:

Form of Voting Agreement

 Exhibit 10.1 
 FORM OF VOTING AGREEMENT 
 THIS VOTING AGREEMENT (this
“Agreement”) dated June 13, 2011, is entered into among Trimeris, Inc., a Delaware Corporation (“Parent”), each of the stockholders listed on Schedule I to this Agreement (each a
“Stockholder” and collectively, the “Stockholders”), and Synageva BioPharma Corp., a Delaware Corporation (the “Company”). 

W I T N E S S E T H: 
 WHEREAS, Parent, Tesla Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Parent (“Merger Sub”), and the Company have entered into an Agreement and Plan
of Merger and Reorganization, dated as of June 13, 2011 (as it may be amended or supplemented from time to time, the “Merger Agreement”), pursuant to which and upon the terms and subject to the conditions thereof, Merger
Sub will be merged with and into the Company, and the Company will be the surviving entity (the “Merger”); 
 WHEREAS, as of the date hereof, each Stockholder is the record and beneficial owner of the number of shares (the “Shares”) of Company Stock, set forth opposite such
Stockholder’s name on Schedule I attached hereto (such Shares, together with any other shares of capital stock of the Company acquired by such Stockholder after the date hereof and during the term of this Agreement (including through the
exercise of any stock options, warrants or any other convertible or exchangeable securities or similar instruments), being collectively referred to herein as such Stockholder’s “Subject Shares”); 

WHEREAS, as a condition to the consummation of the Merger, and in order to induce Parent to enter into the Merger Agreement and
consummate the Merger, Parent has required that each Stockholder agree, and each Stockholder is willing to agree, to the matters set forth herein; 
 NOW, THEREFORE, in contemplation of the foregoing and in consideration of the mutual agreements, covenants, representations and warranties contained herein and intending to be legally bound hereby,
Parent, on the one hand, and each Stockholder, severally and not jointly, on the other hand, agree as follows: 
 Section 1.
Defined Terms. Capitalized terms used but not defined herein have the meanings set forth in the Merger Agreement. 

Section 2. Voting of Shares. 
 (a) Voting. Until this Agreement is terminated in accordance with its terms, Stockholder hereby agrees to vote (or cause to be voted) all of Stockholder’s Subject Shares, at every annual,
special or other meeting of the stockholders of the Company, and at any adjournment or adjournments thereof, or pursuant to any consent in lieu of a meeting or otherwise: 

(i) in favor of the Merger and the adoption of the Merger Agreement and the approval of the transactions contemplated by
the Merger Agreement, and any actions required in furtherance thereof; 

 (ii) against any action or agreement that would result in a breach in any
material respect of any covenant, representation or warranty or any other obligation of the Company under the Merger Agreement; and 
 (iii) against (A) any Acquisition Proposal involving the Company or any of its subsidiaries, or (B) any action that is intended, or would reasonably be expected, to impede, interfere with,
prevent, delay, postpone or adversely affect the Merger or the transactions contemplated by the Merger Agreement. 
 Prior to the termination of
this Agreement, Stockholder shall not enter into any agreement, understanding or arrangement (whether written or oral) with any Person to vote or give instructions in any manner inconsistent with clauses “(i)”, “(ii)” or
“(iii)” of this Section 2(a). 
 (b) Grant of Irrevocable Proxy. 

(i) Contemporaneously with the execution of this Agreement: (i) Stockholder shall deliver to Parent a proxy in the
form attached hereto as Exhibit A, which shall be irrevocable to the fullest extent permitted by law with respect to the securities referred to therein (the “Proxy”); and (ii) if applicable, Stockholder shall cause to be
delivered to Parent an additional proxy (in the form attached hereto as Exhibit A) executed on behalf of the record owner of any outstanding Subject Shares that are owned beneficially (within the meaning of Rule 13d-3 under the Exchange Act) but not
of record by Stockholder. 
 (ii) Stockholder shall not enter into any tender, voting or other agreement,
understanding or arrangement, or grant a proxy or power of attorney with respect to Stockholder’s Subject Shares that is inconsistent with this Agreement or otherwise take any other action with respect to Stockholder’s Subject Shares that
would in any way restrict, limit or interfere with the performance of the Stockholder’s obligations hereunder or the transactions contemplated hereby or under any proxy delivered to Parent by Stockholder or on Stockholder’s behalf.

 Section 3. Fiduciary Responsibilities. If Stockholder (or an affiliate or designee of Stockholder) is or becomes
during the term hereof a director or officer of the Company, Stockholder does not make (or shall not be deemed to have made) any agreement or understanding herein in such person’s capacity as such director or officer of the Company. Without
limiting the generality of the foregoing, Stockholder signs solely in his, her or its capacity as the record and beneficial owner of Stockholder’s Subject Shares and nothing herein shall limit or affect any actions taken by Stockholder (or an
affiliate or designee of Stockholder) in his or her capacity as an officer or director of the Company in exercising his or her or the Company’s or the Company’s board of directors’ rights in connection with the Merger Agreement or
otherwise and such actions shall not be deemed to be a breach of this Agreement. 
 Section 4. Representations and Warranties
of Stockholder. Stockholder represents and warrants to Parent as follows: 
 (a) Binding Agreement.
Stockholder has the capacity to execute and deliver this Agreement and to consummate the transactions contemplated hereby. Stockholder has duly and validly executed and delivered this Agreement and, assuming the due authorization, execution

 
and delivery of this Agreement by Parent, this Agreement constitutes a legal, valid and binding obligation of Stockholder, enforceable against Stockholder in accordance with its terms, except as
such enforceability may be limited by applicable bankruptcy, insolvency, reorganization or other similar laws affecting creditors’ rights generally and by general equitable principles (regardless of whether enforceability is considered in a
proceeding in equity or at law). 
 (b) No Conflict. Neither the execution and delivery of this Agreement
by Stockholder, nor the performance by Stockholder of its obligations hereunder will (i) require any consent, approval, authorization or permit of, registration, declaration or filing (except for such filings as may be required under the
federal securities laws or the HSR Act or as would not prevent, delay or otherwise impair Stockholder’s ability to perform its obligations hereunder) with, or notification to, any Government Authority, (ii) if Stockholder is an entity,
result in a violation of, or default under, or conflict with any provision of its certificate of incorporation, bylaws, partnership agreement, limited liability company agreement or similar organizational documents, (iii) result in a violation
or breach of, or constitute (with or without due notice or lapse of time or both) a default (or give rise to any right of termination, cancellation, or acceleration) under any contract, trust, agreement, instrument, commitment, arrangement or
understanding applicable to Stockholder or Stockholder’s Subject Shares, or result in the creation of a security interest, lien, charge, encumbrance, equity or claim with respect to any of Stockholder’s Subject Shares, except, in the case
of clause (iii), as would not prevent, delay or otherwise impair Stockholder’s ability to perform its obligations hereunder, (iv) require any consent, authorization or approval of any Person other than a Government Authority, except, in
the case of clause (iv), as would not prevent, delay or otherwise impair Stockholder’s ability to perform its obligations hereunder or (v) violate or conflict with any order, writ, injunction, decree, rule, regulation or law applicable to
Stockholder or Stockholder’s Subject Shares. If Stockholder is a married individual and Stockholder’s Subject Shares constitute community property or otherwise need spousal approval in order for this Agreement to be a legal, valid and
binding obligation of Stockholder, this Agreement has been duly authorized, executed and delivered by, and constitutes a legal, valid and binding obligation of, Stockholder’s spouse, enforceable against such spouse in accordance with its terms,
except as such enforceability may be limited by applicable bankruptcy, insolvency, reorganization or other similar laws affecting creditors’ rights generally and by general equitable principles (regardless of whether enforceability is
considered in a proceeding in equity or at law). 
 (c) Ownership of Shares. Stockholder is the record and
beneficial owner of the Shares and options, warrants and any additional rights to acquire Shares set forth opposite Stockholder’s name on Schedule I attached hereto free and clear of any security interests, liens, charges, encumbrances,
equities, claims, options or limitations of whatever nature and free of any other limitation or restriction (including any restriction on the right to vote, sell or otherwise dispose of such Shares), except for any such encumbrances arising
hereunder. Other than as set forth on Schedule I, as of the date of this Agreement, Stockholder does not own (beneficially or otherwise) any shares of Company Stock or any options, warrants, notes or other rights to acquire shares of Company Stock.
No Person has any right to acquire from Stockholder any of the securities set forth on Schedule I and Stockholder has no obligation to sell or dispose of any such securities. Except for the rights granted to Parent under this Agreement, Stockholder
holds exclusive power to vote the Shares set forth opposite Stockholder’s name on Schedule I attached hereto. 

 (d) Broker Fees. No broker, investment banker, financial advisor or
other person is entitled to any broker’s, finder’s, financial advisor’s or other similar fee or commission based upon arrangements made by or on behalf of Stockholder in connection with its entering into this Agreement. 

(e) Accuracy of Representations. The representations and warranties contained in this Agreement are accurate in all
respects as of the date hereof and will be accurate in all respects at all times prior to the termination of this Agreement as if made on and as of any such time or date. 
 Section 5. Transfer and Other Restrictions. Until this Agreement is terminated in accordance with its terms: 
 (a) Certain Prohibited Transfers. Stockholder agrees not to (directly or indirectly): 
 (i) (A) sell, transfer, pledge, encumber, assign, make any short sale of, or enter into any hedging or similar transaction having the same economic effect as a sale, or otherwise dispose of
Stockholder’s Subject Shares or any interest contained therein, or (B) enter into any contract, option or other arrangement or understanding with respect to any matter referred to in clause “(A)” relating to the
Stockholder’s Subject Shares or any interest contained therein (each of the matters in clauses “(A)” and “(B”) collectively referred to herein as a “Transfer”); 

(ii) grant any proxies or powers of attorney or enter into a voting agreement or other arrangement with respect to
Stockholder’s Subject Shares, other than this Agreement; 
 (iii) enter into, or deposit Stockholder’s
Subject Shares into, a voting trust or take any other action which would, or could reasonably be expected to, result in a diminution of the voting power represented by any of Stockholder’s Subject Shares; or 

(iv) commit or agree to take any of the foregoing actions. 

(b) Permitted Transfers. Section 5(a) hereof shall not prohibit a Transfer of Subject Shares by Stockholder
(any such Transfer, a “Permitted Transfer”): (i) if Stockholder is an individual: (A) to any member of Stockholder’s immediate family; or to a trust or other estate planning vehicle for the benefit of
Stockholder or any member of Stockholder’s immediate family; or (B) upon the death of Stockholder to Stockholder’s heirs; (ii) if Stockholder is a partnership or limited liability company, to one or more partners or members of
Stockholder or to an affiliated corporation, trust or other business entity under common control with Stockholder, or if Stockholder is a trust, to a beneficiary; or (iii) to another holder of the capital stock of the Company that has signed a
voting agreement in substantially the form hereof; provided however, that a Transfer referred to on this Section 5(b) shall be permitted only if, as a precondition to such Transfer, the transferee agrees in writing, reasonably satisfactory in
form and substance to Parent, to be bound by all of the terms of this Agreement and provides a Proxy as required by Section 2(b) hereof. 

 (c) Efforts. Stockholder agrees not to take any action which would
make any representation or warranty of Stockholder herein untrue or incorrect in any material respect as of any time prior to the termination hereof or take any action that would have the effect of preventing or disabling it from performing its
obligations under this Agreement. Subject to Section 3 hereof, until this Agreement is terminated in accordance with its terms, Stockholder shall use its reasonable best efforts to take, or cause to be taken, all actions reasonably necessary or
desirable to vote (or cause to be voted) all of Stockholder’s Subject Shares in accordance with Section 2(a) of this Agreement (including executing and delivering additional documents as Parent may request, at the cost and expense of
Parent). 
 (d) Additional Shares. In the event (i) of any stock dividend, stock split,
recapitalization, reclassification, combination or exchange of shares of capital stock of the Company on, of or affecting Stockholder’s Subject Shares or (ii) Stockholder becomes the beneficial owner of any additional shares of Company
Stock or other securities entitling the holder thereof to vote or give consent with respect to the matters set forth in Section 2(a) hereof, then the terms of this Agreement shall apply to the shares of capital stock or other securities of the
Company held by Stockholder immediately following the effectiveness of the events described in clause (i) or Stockholder becoming the beneficial owner thereof, as described in clause (ii), as though they were Stockholder’s Subject Shares
hereunder. Stockholder hereby agrees, until this Agreement is terminated in accordance with its terms, to notify Parent of the number of any new shares of Company Stock acquired by Stockholder, if any, after the date hereof. 

Section 6. Appraisal Rights. Stockholder hereby agrees not to exercise any appraisal rights or any dissenters’ rights that
Stockholder may have (whether under applicable law or otherwise) or could potentially have or acquire in connection with the Merger Agreement, and the transactions contemplated by the Merger Agreement, including the Merger. 

Section 7. No Solicitation. Until this Agreement is terminated in accordance with its terms, Stockholder shall not, nor shall
Stockholder permit any investment banker, attorney or other advisor or representative of the Stockholder to, directly or indirectly through another Person, take any action that the Company is prohibited from taking or authorizing to be taken
pursuant to Section 5.3 of the Merger Agreement; provided, however, that any action which is permitted by the Merger Agreement to be taken by Stockholder (or an affiliate or designee of Stockholder) in his or her capacity as a
director or officer of the Company or which is permitted by Section 3 hereof shall not be prohibited by the foregoing so long as such action is taken by Stockholder (or such affiliate or designee) in his or her actual capacity as a director or
officer of the Company. 
 Section 8. Termination of Company Agreements. Reference is made to that certain Note Purchase
Agreement by and between the Company and the Investors listed on Schedule 1.1 thereto, dated as of March 15, 2011 (the “Note Purchase Agreement”), that certain Information and Registration Rights Agreement by and between
the Company and the Investors listed on Schedule 1.1. thereto, dated as of April 1, 2009, as amended September 25, 2009 and March 15, 2011 (the “Registration Rights Agreement”), that certain Amended and
Restated Stockholders’ Agreement by and between the Company and the Investors listed on Exhibit A thereto, dated as of April 1, 2009, as amended (the “Stockholders’ Agreement”), and that certain

 
Right of First Refusal and Co-Sale Agreement by and between the Company and the Investors and Common Holders listed on Exhibits A and B, respectively, thereto, dated March 25, 2010 (the
“Right of First Refusal Agreement”). Pursuant to Section 8.6 of the Note Purchase Agreement, Section 18.5 of the Registration Rights Agreement, Section XI of the Stockholders’ Agreement, and Section 11.5
of the Right of First Refusal Agreement, Stockholder hereby agrees that each of the Note Purchase Agreement, Stockholders’ Agreement, and Right of First Refusal Agreement, and Sections 2, 3 and 4 of the Registration Rights Agreement shall be
terminated in their entirety with no further force and effect at the Effective Time. In addition, Stockholder, the Company and the Parent further agree that they shall each take all actions necessary to amend the Registration Rights Agreement so
that the surviving provisions of the Registration Rights Agreement continue to apply to the shares of Parent Common Stock received in exchange for Registrable Securities (as defined in the Registration Rights Agreement) to the extent set forth in
the Registration Rights Agreement, treating for this purpose the consummation of the Merger as a Qualified IPO (as defined in the Registration Rights Agreement). 
 Section 9. Specific Enforcement; Jurisdiction. Stockholder agrees that irreparable damage would occur in the event that any of the provisions of this Agreement or the Proxy were not performed in
accordance with the terms hereof or were otherwise breached and that Parent shall be entitled to specific performance of the terms hereof in addition to any other remedy which may be available at law or in equity. It is accordingly agreed that
Parent will be entitled to an injunction or injunctions to prevent breaches of this Agreement or the Proxy and to enforce specifically the terms and provisions of this Agreement or the Proxy in any state or federal court located in the State of
Delaware or in the Court of Chancery of the State of Delaware, the foregoing being in addition to any other remedy to which they are entitled at law or in equity. In addition, each of Stockholder and Parent hereto (a) consents to submit itself
to the personal jurisdiction of any state or federal court located in the State of Delaware or in the Court of Chancery of the State of Delaware in the event any dispute arises out of this Agreement or any of the transactions contemplated by this
Agreement or the Proxy, (b) agrees that it will not attempt to deny or defeat such personal jurisdiction by motion or other request for leave from any such court, and (c) agrees that it will not bring any action relating to this Agreement
or the Proxy or any of the transactions contemplated by this Agreement in any court other than a state or federal court located in the State of Delaware or the Court of Chancery of the State of Delaware. 

Section 10. Termination. This Agreement shall terminate and cease to have any force or effect on the earliest of (a) the
termination of the Merger Agreement in accordance with its terms, (b) the written agreement of Parent and Stockholder to terminate this Agreement, (c) the consummation of the Merger, and (d) the amendment, modification or waiver of
the Merger Agreement to alter the Merger Consideration in a manner adverse to Stockholder unless such amendment, modification or waiver has been consented to by Stockholder in writing prior to or simultaneously with such amendment, modification or
waiver; provided, however, that (i) Sections 9 through 20 shall survive any termination of this Agreement and (ii) termination of this Agreement shall not relieve any party from liability for any breach of its obligations
hereunder committed prior to such termination. 
 Section 11. Notices. All notices and other communications hereunder
shall be in writing and shall be deemed to have been duly given if delivered personally, mailed by 

 
certified mail (return receipt requested) or sent by overnight carrier or by facsimile (upon confirmation of receipt) to the parties at the following addresses or at such other as shall be
specified by the parties by like notice: (a) if to Parent, to the appropriate address set forth in Section 9.4 of the Merger Agreement (with a copy to Paul, Hastings, Janofsky & Walker, LLP); (b) if to the Company, to the
appropriate address set forth in Section 9.4 of the Merger Agreement (with a copy to Ropes & Gray LLP), and (c) if to Stockholder, to the appropriate address set forth on Schedule I hereto. 

Section 12. Stockholder Information. Stockholder agrees to permit Parent to publish and disclose in the Registration Statement,
the Joint Proxy Statement and any other public disclosure that Parent and the Company mutually determine to be necessary and desirable in connection with the Merger and any of the other transactions contemplated by the Merger Agreement the identity
of Stockholder and the ownership of securities of the Company or Parent and the nature of Stockholder’s commitments, arrangements and understandings under this Agreement and the Proxy. Parent shall provide drafts of such disclosures to be made
in the Registration Statement, Joint Proxy Statement and such other public disclosures to Stockholder reasonably in advance of such disclosures and shall consider in good faith any comments provided by Stockholder in a timely manner. 

Section 13. Certain Events. Stockholder agrees that this Agreement and the obligations hereunder shall attach to
Stockholder’s Subject Shares and shall be binding upon any person or entity to which legal or beneficial ownership of Stockholder’s Subject Shares shall pass, whether by operation of law or otherwise, including Stockholder’s heirs,
guardians, administrators or successors. 
 Section 14. Entire Agreement. This Agreement (including the documents and
instruments referred to herein) constitutes the entire agreement and supersedes all other prior agreements and understandings, both written and oral, among the parties, or any of them, with respect to the subject matter hereof. 

Section 15. Amendment. This Agreement may not be modified, amended, altered or supplemented except upon the execution and delivery
of a written agreement executed by Parent and Stockholder, except that any modification, amendment, alteration or supplement of Section 8 shall require the execution and delivery of a written agreement executed by Parent, Stockholder and the
Company. 
 Section 16. Successors and Assigns. Neither this Agreement nor any rights or obligations hereunder shall be
assigned (by operation of law or otherwise) or delegated to any Person without the prior written consent of the other parties hereto and any attempted assignment or delegation thereof shall be void ab initio. This Agreement will be binding
upon, inure to the benefit of and be enforceable by each party and such party’s heirs, beneficiaries, executors, successors, representatives and permitted assigns. Nothing in this Agreement is intended to confer on any Person (other than the
parties hereto and their successors and permitted assigns) any rights or remedies of any nature. 
 Section 17.
Counterparts. This Agreement may be executed in any number of counterparts and by different parties hereto in separate counterparts, and delivered by means of 

 
facsimile transmission, electronic delivery or otherwise, each of which when so executed and delivered shall be deemed to be an original and all of which when taken together shall constitute one
and the same agreement and shall be sufficient to bind the parties hereto to the terms and conditions of this Agreement. 

Section 18. GOVERNING LAW. THIS AGREEMENT SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF
DELAWARE REGARDLESS OF THE LAWS THAT MIGHT OTHERWISE GOVERN UNDER APPLICABLE PRINCIPLES OF CONFLICTS OF LAW THEREOF. 
 Section
19. Waiver. Subject to the remainder of this Section 19, at any time prior to the termination of this Agreement, any party hereto may: (i) extend the time for performance of any of the obligations or other acts of the other parties
to this Agreement; (ii) waive any inaccuracy in or breach of any representation, warranty, covenant or obligation of the other party to this Agreement or in any document (including the Proxy) delivered pursuant to this Agreement; and
(iii) waive compliance with any covenant, obligation or condition for the benefit of such party contained in this Agreement. No failure on the part of any party to exercise any power, right, privilege or remedy under this Agreement shall
operate as a waiver of such power, right, privilege or remedy; and no single or partial exercise of any such power, right, privilege or remedy shall preclude any other or further exercise thereof or of any other power, right, privilege or remedy. No
party shall be deemed to have waived any power, right, privilege or remedy available to such party arising out of this Agreement, unless such waiver is expressly set forth in a written instrument duly executed and delivered by the party waiving such
power, right, privilege or remedy; and any such waiver shall not be applicable or have any effect except in the specific instance in which it is given. 
 Section 20. Severability. If any provision of this Agreement shall be held to be illegal, invalid or unenforceable under any applicable law, then such contravention or invalidity shall not
invalidate the entire Agreement. Such provision shall be deemed to be modified to the extent necessary to render it legal, valid and enforceable, and if no such modification shall render it legal, valid and enforceable, then this Agreement shall be
construed as if not containing the provision held to be invalid, and the rights and obligations of the parties shall be construed and enforced accordingly. 
 Section 21. Several Obligations. Notwithstanding anything to the contrary in this Agreement, the obligations of each Stockholder who is a signatory to this Agreement are several and not joint. In
no event shall any Stockholder who is a signatory to this Agreement have any liability or obligation with respect to the acts or omissions of any other Stockholder who is also a signatory to this Agreement. 

Section 22. Headings. The headings contained in this Agreement are for reference purposes only and shall not affect in any way the
meaning or interpretation of this Agreement. 
 Section 23. Other Agreements. Contemporaneously with the execution of
this Agreement, Parent and Company are entering into agreements with certain other holders of Company Stock on the same terms as this Agreement (the “Other Voting Agreements”). Neither

 
Parent nor the Company shall enter into any amendment or modification of, or grant any waiver under, any Other Voting Agreement, unless the same amendment or modification of, or grant of waiver
under, this Agreement is offered to Stockholder. 
 [The remainder of this page is intentionally blank.] 

 IN WITNESS WHEREOF, each of the parties hereto has caused this Agreement to be signed,
individually or by its respective officer thereunto duly authorized, as of the date first written above. 
  

			
	TRIMERIS, INC.
		
	By:	 	 
		 	Name: 
		 	Title: 
	
	STOCKHOLDER:
		
	By:	 	 
		 	Name:
		 	Title:

 IN WITNESS WHEREOF, each of the parties hereto has caused this Agreement to be signed,
individually or by its respective officer thereunto duly authorized, as of the date first written above. 
  

			
	SYNAGEVA BIOPHARMA CORP.:
		
	By:	 	 
		 	Name:
		 	Title:

 SCHEDULE I TO 
 VOTING AGREEMENT 
  

																	
	 Name
	  	Address	  	Shares of
Company Series
A-2 Preferred
Stock	  	Shares of
Company Series
B-2 Preferred
Stock	  	Shares of
Company Series
C-2 Preferred
Stock	  	Shares of
Company Series
D-2 Preferred
Stock	  	Shares of
Company
Common Stock	  	Shares of
Company Series
D-2 Preferred
Stock Issuable
Upon
Conversion of
Company
Notes	  	Shares of
Company
Common Stock
Issuable Upon
Exercise
of
Company Stock
Options

 EXHIBIT A 

FORM OF IRREVOCABLE PROXY 

 IRREVOCABLE PROXY 

Each undersigned stockholder (each a “Stockholder”) of Synageva BioPharma Corp., a Delaware corporation (the
“Company”), severally and not jointly, hereby irrevocably (to the fullest extent permitted by law) appoints and constitutes Trimeris, Inc., a Delaware corporation (“Parent”) and Martin Mattingly and James Thomas, solely in
their capacities as executive officers of Parent, and each of them, the attorneys and proxies of the Stockholder, with full power of substitution and resubstitution, to the full extent of Stockholder’s rights with respect to the outstanding
shares of capital stock of the Company owned of record by the Stockholder as of the date of this proxy, which shares are specified on the final page of this proxy. (The shares of the capital stock of the Company referred to in the immediately
preceding sentence are referred to as the “Shares.”) Upon the execution of this proxy, all prior proxies given by Stockholder with respect to any of the Shares are hereby revoked, and Stockholder agrees that no subsequent proxies
inconsistent with this Proxy will be given with respect to any of the Shares. 
 This proxy is irrevocable, is coupled with an
interest and is granted in connection with, and as security for, the Voting Agreement, dated as of the date hereof, between Parent, Stockholder and the Company (the “Voting Agreement”), and is granted in consideration of and as an
inducement to Parent entering into the Agreement and Plan of Merger and Reorganization, dated as of the date hereof, among Parent, Tesla Merger Sub, Inc., a Delaware corporation and wholly-owned subsidiary of Parent (“Merger Sub”),
and the Company (the “Merger Agreement”), whereby the Merger Sub will be merged with and into the Company (the “Merger”). This proxy will terminate on the termination of the Voting Agreement in accordance with its
terms. 
 Prior to the termination of the Voting Agreement, the attorneys and proxies named above will be empowered, and may
exercise this proxy, to vote any Shares owned by Stockholder, at any meeting of the stockholders of the Company, however called, or at any adjournment or postponement thereof and on every action or approval by written consent of the stockholders of
the Company: 
 (i) in favor of the Merger and the adoption of the Merger Agreement and the approval of the
transactions contemplated by the Merger Agreement, and any actions required in furtherance thereof; 
 (ii)
against any action or agreement that would result in a breach in any material respect of any covenant, representation or warranty or any other obligation of the Company under the Merger Agreement; and 

(iii) against (a) any Acquisition Proposal (as defined in the Merger Agreement) involving the Company or any of its
subsidiaries, or (b) any action that is intended, or would reasonably be expected, to impede, interfere with, prevent, delay, postpone or adversely affect the Merger or the transactions contemplated by the Merger Agreement. 

Stockholder may vote the Shares on all other matters not referred to in this proxy, and the attorneys and proxies named above may not
exercise this proxy with respect to such other matters. 

 This proxy shall be binding upon the heirs, estate, executors, personal representatives,
successors and assigns of the Stockholder (including any transferee of any of the Shares). 
 Any term or provision of this
proxy that is invalid or unenforceable in any situation in any jurisdiction shall not affect the validity or enforceability of the remaining terms and provisions of this proxy or the validity or enforceability of the offending term or provision in
any other situation or in any other jurisdiction. Upon such determination that any term or provision is invalid, illegal or incapable of being enforced, the parties hereto shall negotiate in good faith to modify this proxy so as to effect the
original intent of the parties as closely as possible in an acceptable manner to the end that the transactions contemplated hereby are fulfilled to the fullest extent possible. 
 [Signature page follows] 

					
	Dated: June 13, 2011	 		 	STOCKHOLDER
			
	 	 		 	  
		 		 	Signature
			
	 	 		 	  
		 		 	Printed Name
			
		 		 	Number of shares of capital stock of Company owned of record as of the date of this proxy:Form of Voting Agreement

 Exhibit 10.2 
 FORM OF VOTING AGREEMENT 
 THIS VOTING AGREEMENT (this
“Agreement”) dated June 13, 2011, is entered into among Synageva BioPharma Corp., a Delaware corporation (“Synageva”), and each of the stockholders listed on Schedule I to this Agreement
(each a “Stockholder” and collectively, the “Stockholders”). 
 W I T N E S
S E T H: 
 WHEREAS, Trimeris, Inc., a Delaware corporation (“Trimeris”), Tesla Merger
Sub, Inc., a Delaware corporation and wholly owned subsidiary of Trimeris (“Merger Sub”), and Synageva have entered into an Agreement and Plan of Merger and Reorganization, dated as of June 13, 2011 (as it may be amended
or supplemented from time to time, the “Merger Agreement”), pursuant to which and upon the terms and subject to the conditions thereof, Merger Sub will be merged with and into Synageva, and Synageva will be the surviving
entity (the “Merger”); 
 WHEREAS, as of the date hereof, each Stockholder is the record and
beneficial owner of the number of shares (the “Shares”) of Parent Common Stock, set forth opposite such Stockholder’s name on Schedule I attached hereto (such Shares, together with any other shares of capital stock of
Trimeris acquired by such Stockholder after the date hereof and during the term of this Agreement (including through the exercise of any stock options, warrants or any other convertible or exchangeable securities or similar instruments), being
collectively referred to herein as such Stockholder’s “Subject Shares”); 
 WHEREAS, as a
condition to the consummation of the Merger, and in order to induce Synageva to enter into the Merger Agreement and consummate the Merger, Synageva has required that each Stockholder agree, and each Stockholder is willing to agree, to the matters
set forth herein; 
 NOW, THEREFORE, in contemplation of the foregoing and in consideration of the mutual agreements,
covenants, representations and warranties contained herein and intending to be legally bound hereby, Synageva, on the one hand, and each Stockholder, severally and not jointly, on the other hand, agree as follows: 

Section 1. Defined Terms. Capitalized terms used but not defined herein have the meanings set forth in the Merger Agreement.

 Section 2. Voting of Shares. 
 (a) Voting. Until this Agreement is terminated in accordance with its terms, Stockholder hereby agrees to vote (or cause to be voted) all of Stockholder’s Subject Shares, at every annual,
special or other meeting of the stockholders of Trimeris, and at any adjournment or adjournments thereof, or pursuant to any consent in lieu of a meeting or otherwise: 

 (i) in favor of the approval the Parent Charter Amendment, the issuance of
shares of Parent Common Stock pursuant to the Merger Agreement, and any actions required in furtherance thereof; 

(ii) against any action or agreement that would result in a breach in any material respect of any covenant, representation
or warranty or any other obligation of Trimeris under the Merger Agreement; and 
 (iii) against (A) any
Acquisition Proposal involving Trimeris or any of its subsidiaries, or (B) any action that is intended, or would reasonably be expected, to impede, interfere with, prevent, delay, postpone or adversely affect the Merger or the transactions
contemplated by the Merger Agreement. 
 Prior to the termination of this Agreement, Stockholder shall not enter into any agreement,
understanding or arrangement (whether written or oral) with any Person to vote or give instructions in any manner inconsistent with clauses “(i)”, “(ii)” or “(iii)” of this Section 2(a). 

(b) Grant of Irrevocable Proxy. 

(i) Contemporaneously with the execution of this Agreement: (i) Stockholder shall deliver to Synageva a proxy in the
form attached hereto as Exhibit A, which shall be irrevocable to the fullest extent permitted by law with respect to the securities referred to therein (the “Proxy”); and (ii) if applicable, Stockholder shall cause to be
delivered to Synageva an additional proxy (in the form attached hereto as Exhibit A) executed on behalf of the record owner of any outstanding Subject Shares that are owned beneficially (within the meaning of Rule 13d-3 under the Exchange Act) but
not of record by Stockholder. 
 (ii) Stockholder shall not enter into any tender, voting or other agreement,
understanding or arrangement, or grant a proxy or power of attorney with respect to Stockholder’s Subject Shares that is inconsistent with this Agreement or otherwise take any other action with respect to Stockholder’s Subject Shares that
would in any way restrict, limit or interfere with the performance of the Stockholder’s obligations hereunder or the transactions contemplated hereby or under any proxy delivered to Synageva by Stockholder or on Stockholder’s behalf.

 Section 3. Fiduciary Responsibilities. If Stockholder (or an affiliate or designee of Stockholder) is or becomes
during the term hereof a director or officer of Trimeris, Stockholder does not make (or shall not be deemed to have made) any agreement or understanding herein in such person’s capacity as such director or officer of Trimeris. Without limiting
the generality of the foregoing, Stockholder signs solely in his, her or its capacity as the record and beneficial owner of Stockholder’s Subject Shares and nothing herein shall limit or affect any actions taken by Stockholder (or an affiliate
or designee of Stockholder) in his or her capacity as an officer or director of Trimeris in exercising his or her or Trimeris’ or Trimeris’ board of directors’ rights in connection with the Merger Agreement or otherwise and such
actions shall not be deemed to be a breach of this Agreement. 

 Section 4. Representations and Warranties of Stockholder. Stockholder represents and
warrants to Synageva as follows: 
 (a) Binding Agreement. Stockholder has the capacity to execute and
deliver this Agreement and to consummate the transactions contemplated hereby. Stockholder has duly and validly executed and delivered this Agreement and, assuming the due authorization, execution and delivery of this Agreement by Synageva, this
Agreement constitutes a legal, valid and binding obligation of Stockholder, enforceable against Stockholder in accordance with its terms, except as such enforceability may be limited by applicable bankruptcy, insolvency, reorganization or other
similar laws affecting creditors’ rights generally and by general equitable principles (regardless of whether enforceability is considered in a proceeding in equity or at law). 

(b) No Conflict. Neither the execution and delivery of this Agreement by Stockholder, nor the performance by
Stockholder of its obligations hereunder will (i) require any consent, approval, authorization or permit of, registration, declaration or filing (except for such filings as may be required under the federal securities laws or the HSR Act or as
would not prevent, delay or otherwise impair Stockholder’s ability to perform its obligations hereunder) with, or notification to, any Government Authority, (ii) if Stockholder is an entity, result in a violation of, or default under, or
conflict with any provision of its certificate of incorporation, bylaws, partnership agreement, limited liability company agreement or similar organizational documents, (iii) result in a violation or breach of, or constitute (with or without
due notice or lapse of time or both) a default (or give rise to any right of termination, cancellation, or acceleration) under any contract, trust, agreement, instrument, commitment, arrangement or understanding applicable to Stockholder or
Stockholder’s Subject Shares, or result in the creation of a security interest, lien, charge, encumbrance, equity or claim with respect to any of Stockholder’s Subject Shares, except, in the case of clause (iii), as would not prevent,
delay or otherwise impair Stockholder’s ability to perform its obligations hereunder, (iv) require any consent, authorization or approval of any Person other than a Government Authority, except, in the case of clause (iv), as would not
prevent, delay or otherwise impair Stockholder’s ability to perform its obligations hereunder or (v) violate or conflict with any order, writ, injunction, decree, rule, regulation or law applicable to Stockholder or Stockholder’s
Subject Shares. If Stockholder is a married individual and Stockholder’s Subject Shares constitute community property or otherwise need spousal approval in order for this Agreement to be a legal, valid and binding obligation of Stockholder,
this Agreement has been duly authorized, executed and delivered by, and constitutes a legal, valid and binding obligation of, Stockholder’s spouse, enforceable against such spouse in accordance with its terms, except as such enforceability may
be limited by applicable bankruptcy, insolvency, reorganization or other similar laws affecting creditors’ rights generally and by general equitable principles (regardless of whether enforceability is considered in a proceeding in equity or at
law). 
 (c) Ownership of Shares. Stockholder is the record and beneficial owner of the Shares and
options, warrants and any additional rights to acquire Shares set forth opposite Stockholder’s name on Schedule I attached hereto free and clear of any security interests, liens, charges, encumbrances, equities, claims, options or limitations
of whatever nature and free of any other limitation or restriction (including any restriction on the right to vote, sell or otherwise dispose of such Shares), except for any such encumbrances arising hereunder. Other than as set forth on Schedule I,
as of the date of this Agreement, Stockholder does not own (beneficially or 

 
otherwise) any shares of Parent Common Stock or any options, warrants, notes or other rights to acquire shares of Parent Common Stock. No Person has any right to acquire from Stockholder any of
the securities set forth on Schedule I and Stockholder has no obligation to sell or dispose of any such securities. Except for the rights granted to Synageva under this Agreement, Stockholder holds exclusive power to vote the Shares set forth
opposite Stockholder’s name on Schedule I attached hereto. 
 (d) Broker Fees. No broker, investment
banker, financial advisor or other person is entitled to any broker’s, finder’s, financial advisor’s or other similar fee or commission based upon arrangements made by or on behalf of Stockholder in connection with its entering into
this Agreement. 
 (e) Accuracy of Representations. The representations and warranties contained in this
Agreement are accurate in all respects as of the date hereof and will be accurate in all respects at all times prior to the termination of this Agreement as if made on and as of any such time or date. 

Section 5. Transfer and Other Restrictions. Until this Agreement is terminated in accordance with its terms: 

(a) Certain Prohibited Transfers. Stockholder agrees not to (directly or indirectly): 

(i) (A) sell, transfer, pledge, encumber, assign, make any short sale of, or enter into any hedging or similar transaction
having the same economic effect as a sale, or otherwise dispose of Stockholder’s Subject Shares or any interest contained therein, or (B) enter into any contract, option or other arrangement or understanding with respect to any matter
referred to in clause “(A)” relating to the Stockholder’s Subject Shares or any interest contained therein (each of the matters in clauses “(A)” and “(B”) collectively referred to herein as a
“Transfer”); 
 (ii) grant any proxies or powers of attorney or enter into
a voting agreement or other arrangement with respect to Stockholder’s Subject Shares, other than this Agreement; 
 (iii) enter into, or deposit Stockholder’s Subject Shares into, a voting trust or take any other action which would, or could reasonably be expected to, result in a diminution of the voting power
represented by any of Stockholder’s Subject Shares; or 
 (iv) commit or agree to take any of the foregoing
actions. 
 (b) Permitted Transfers. Neither Section 5(a) nor Section 7 hereof shall prohibit a
Transfer of Subject Shares by Stockholder (any such Transfer, a “Permitted Transfer”): (i) if Stockholder is an individual: (A) to any member of Stockholder’s immediate family; or to a trust or other estate
planning vehicle for the benefit of Stockholder or any member of Stockholder’s immediate family; or (B) upon the death of Stockholder to Stockholder’s heirs; (ii) if Stockholder is a partnership or limited liability company, to
one or more partners or members of 

 
Stockholder or to an affiliated corporation, trust or other business entity under common control with Stockholder; or (iii) to another holder of the capital stock of Trimeris that has signed
a voting agreement in substantially the form hereof; provided however, that a Transfer referred to on this Section 5(b) shall be permitted only if, as a precondition to such Transfer, the transferee agrees in writing, reasonably satisfactory in
form and substance to Synageva, to be bound by all of the terms of this Agreement and provides a Proxy as required by Section 2(b) hereof. 
 (c) Efforts. Stockholder agrees not to take any action which would make any representation or warranty of Stockholder herein untrue or incorrect in any material respect as of any time prior to the
termination hereof or take any action that would have the effect of preventing or disabling it from performing its obligations under this Agreement. Subject to Section 3 hereof, until this Agreement is terminated in accordance with its terms,
Stockholder shall use its reasonable best efforts to take, or cause to be taken, all actions reasonably necessary or desirable to vote (or cause to be voted) all of Stockholder’s Subject Shares in accordance with Section 2(a) of this
Agreement (including executing and delivering additional documents as Synageva may request, at the cost and expense of Synageva). 
 (d) Additional Shares. In the event (i) of any stock dividend, stock split, recapitalization, reclassification, combination or exchange of shares of capital stock of Trimeris on, of or
affecting Stockholder’s Subject Shares or (ii) Stockholder becomes the beneficial owner of any additional shares of Parent Common Stock or other securities entitling the holder thereof to vote or give consent with respect to the matters
set forth in Section 2(a) hereof, then the terms of this Agreement shall apply to the shares of capital stock or other securities of Trimeris held by Stockholder immediately following the effectiveness of the events described in clause
(i) or Stockholder becoming the beneficial owner thereof, as described in clause (ii), as though they were Stockholder’s Subject Shares hereunder. Stockholder hereby agrees, until this Agreement is terminated in accordance with its terms,
to notify Synageva of the number of any new shares of Parent Common Stock acquired by Stockholder, if any, after the date hereof. 
 Section 6. Appraisal Rights. Stockholder hereby agrees not to exercise any appraisal rights or any dissenters’ rights that Stockholder may have (whether under applicable law or otherwise) or
could potentially have or acquire in connection with the Merger Agreement, and the transactions contemplated by the Merger Agreement, including the Merger. 
 Section 7. No Solicitation. Until this Agreement is terminated in accordance with its terms, Stockholder shall not, nor shall Stockholder permit any investment banker, attorney or other advisor or
representative of the Stockholder to, directly or indirectly through another Person, take any action that Trimeris is prohibited from taking or authorizing to be taken pursuant to Section 5.4 of the Merger Agreement; provided,
however, that any action which is permitted by the Merger Agreement to be taken by Stockholder (or an affiliate or designee of Stockholder) in his or her capacity as a director or officer of Trimeris or which is permitted by Section 3
hereof shall not be prohibited by the foregoing so long as such action is taken by Stockholder (or such affiliate or designee) in his or her actual capacity as a director or officer of Trimeris. 

Section 8. Specific Enforcement; Jurisdiction. Stockholder agrees that irreparable damage would occur in the event that any of the
provisions of this Agreement or the 

 
Proxy were not performed in accordance with the terms hereof or were otherwise breached and that Synageva shall be entitled to specific performance of the terms hereof in addition to any other
remedy which may be available at law or in equity. It is accordingly agreed that Synageva will be entitled to an injunction or injunctions to prevent breaches of this Agreement or the Proxy and to enforce specifically the terms and provisions of
this Agreement or the Proxy in any state or federal court located in the State of Delaware or in the Court of Chancery of the State of Delaware, the foregoing being in addition to any other remedy to which they are entitled at law or in equity. In
addition, each of Stockholder and Synageva hereto (a) consents to submit itself to the personal jurisdiction of any state or federal court located in the State of Delaware or in the Court of Chancery of the State of Delaware in the event any
dispute arises out of this Agreement or any of the transactions contemplated by this Agreement or the Proxy, (b) agrees that it will not attempt to deny or defeat such personal jurisdiction by motion or other request for leave from any such
court, and (c) agrees that it will not bring any action relating to this Agreement or the Proxy or any of the transactions contemplated by this Agreement in any court other than a state or federal court located in the State of Delaware or the
Court of Chancery of the State of Delaware. 
 Section 9. Termination. This Agreement shall terminate and cease to have
any force or effect on the earliest of (a) the termination of the Merger Agreement in accordance with its terms, (b) the written agreement of Synageva and Stockholder to terminate this Agreement, (c) the consummation of the Merger,
and (d) the amendment, modification or waiver of the Merger Agreement to alter the Merger Consideration in a manner adverse to Stockholder unless such amendment, modification or waiver has been consented to by Stockholder in writing prior to or
simultaneously with such amendment, modification or waiver; provided, however, that (i) Sections 8 through 19 shall survive any termination of this Agreement and (ii) termination of this Agreement shall not relieve any party
from liability for any breach of its obligations hereunder committed prior to such termination. 
 Section 10. Notices.
All notices and other communications hereunder shall be in writing and shall be deemed to have been duly given if delivered personally, mailed by certified mail (return receipt requested) or sent by overnight carrier or by facsimile (upon
confirmation of receipt) to the parties at the following addresses or at such other as shall be specified by the parties by like notice: (a) if to Trimeris, to the appropriate address set forth in Section 9.4 of the Merger Agreement (with
a copy to Paul, Hastings, Janofsky & Walker, LLP); (b) if to Synageva, to the appropriate address set forth in Section 9.4 of the Merger Agreement (with a copy to Ropes & Gray LLP), and (c) if to Stockholder, to the
appropriate address set forth on Schedule I hereto. 
 Section 11. Stockholder Information. Stockholder agrees to permit
Trimeris to publish and disclose in the Registration Statement, the Joint Proxy Statement and any other public disclosure that Synageva and Trimeris mutually determine to be necessary and desirable in connection with the Merger and any of the other
transactions contemplated by the Merger Agreement the identity of Stockholder and the ownership of securities of Trimeris or Synageva and the nature of Stockholder’s commitments, arrangements and understandings under this Agreement and the
Proxy. Trimeris shall provide drafts of such disclosures to be made in the Registration Statement and Joint Proxy Statement and such other public disclosures to 

 
Stockholder reasonably in advance of such disclosures and shall consider in good faith any comments provided by Stockholder in a timely manner. 

Section 12. Certain Events. Stockholder agrees that this Agreement and the obligations hereunder shall attach to
Stockholder’s Subject Shares and shall be binding upon any person or entity to which legal or beneficial ownership of Stockholder’s Subject Shares shall pass, whether by operation of law or otherwise, including Stockholder’s heirs,
guardians, administrators or successors. 
 Section 13. Entire Agreement. This Agreement (including the documents and
instruments referred to herein) constitutes the entire agreement and supersedes all other prior agreements and understandings, both written and oral, among the parties, or any of them, with respect to the subject matter hereof. 

Section 14. Amendment. This Agreement may not be modified, amended, altered or supplemented except upon the execution and delivery
of a written agreement executed by Synageva and Stockholder. 
 Section 15. Successors and Assigns. Neither this
Agreement nor any rights or obligations hereunder shall be assigned (by operation of law or otherwise) or delegated to any Person without the prior written consent of the other parties hereto and any attempted assignment or delegation thereof shall
be void ab initio. This Agreement will be binding upon, inure to the benefit of and be enforceable by each party and such party’s heirs, beneficiaries, executors, successors, representatives and permitted assigns. Nothing in this
Agreement is intended to confer on any Person (other than the parties hereto and their successors and permitted assigns) any rights or remedies of any nature. 
 Section 16. Counterparts. This Agreement may be executed in any number of counterparts and by different parties hereto in separate counterparts, and delivered by means of facsimile transmission,
electronic delivery or otherwise, each of which when so executed and delivered shall be deemed to be an original and all of which when taken together shall constitute one and the same agreement and shall be sufficient to bind the parties hereto to
the terms and conditions of this Agreement. 
 Section 17. GOVERNING LAW. THIS AGREEMENT SHALL BE GOVERNED BY, AND
CONSTRUED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF DELAWARE REGARDLESS OF THE LAWS THAT MIGHT OTHERWISE GOVERN UNDER APPLICABLE PRINCIPLES OF CONFLICTS OF LAW THEREOF. 
 Section 18. Waiver. Subject to the remainder of this Section 19, at any time prior to the termination of this Agreement, any party hereto may: (i) extend the time for performance of any
of the obligations or other acts of the other parties to this Agreement; (ii) waive any inaccuracy in or breach of any representation, warranty, covenant or obligation of the other party to this Agreement or in any document (including the
Proxy) delivered pursuant to this Agreement; and (iii) waive compliance with any covenant, obligation or condition for the benefit of such party contained in this Agreement. No failure on the part of any party to exercise any power, right,
privilege or remedy under this Agreement shall operate as a waiver of such power, 

 
right, privilege or remedy; and no single or partial exercise of any such power, right, privilege or remedy shall preclude any other or further exercise thereof or of any other power, right,
privilege or remedy. No party shall be deemed to have waived any power, right, privilege or remedy available to such party arising out of this Agreement, unless such waiver is expressly set forth in a written instrument duly executed and delivered
by the party waiving such power, right, privilege or remedy; and any such waiver shall not be applicable or have any effect except in the specific instance in which it is given. 

Section 19. Severability. If any provision of this Agreement shall be held to be illegal, invalid or unenforceable under any
applicable law, then such contravention or invalidity shall not invalidate the entire Agreement. Such provision shall be deemed to be modified to the extent necessary to render it legal, valid and enforceable, and if no such modification shall
render it legal, valid and enforceable, then this Agreement shall be construed as if not containing the provision held to be invalid, and the rights and obligations of the parties shall be construed and enforced accordingly. 

Section 20. Several Obligations. Notwithstanding anything to the contrary in this Agreement, the obligations of each Stockholder
who is a signatory to this Agreement are several and not joint. In no event shall any Stockholder who is a signatory to this Agreement have any liability or obligation with respect to the acts or omissions of any other Stockholder who is also a
signatory to this Agreement. 
 Section 21. Headings. The headings contained in this Agreement are for reference purposes
only and shall not affect in any way the meaning or interpretation of this Agreement. 
 [The remainder of this page is
intentionally blank.] 

 IN WITNESS WHEREOF, each of the parties hereto has caused this Agreement to be signed,
individually or by its respective officer thereunto duly authorized, as of the date first written above. 
  

			
	SYNAGEVA BIOPHARMA CORP.
		
	By:	 	 
	 Name:
	 	
	 Title:
	 	
	
	STOCKHOLDER:
		
	By:	 	 
		 	Name: 

 [Signature Page to Voting
Agreement] 

 SCHEDULE I TO 
 VOTING AGREEMENT 
  

							
	 Name
	  	Address	  	Shares of Parent Common Stock	  	Options to Purchase Parent Common Stock

 EXHIBIT A 

FORM OF IRREVOCABLE PROXY 

 IRREVOCABLE PROXY 

Each undersigned stockholder (each a “Stockholder”) of Trimeris, Inc., a Delaware corporation (“Trimeris”),
severally and not jointly, hereby irrevocably (to the fullest extent permitted by law) appoints and constitutes Synageva BioPharma Corp., a Delaware corporation (“Synageva”) and Sanj Patel and Carsten Boess, solely in their capacities as
executive officers of Synageva, and each of them, the attorneys and proxies of the Stockholder, with full power of substitution and resubstitution, to the full extent of Stockholder’s rights with respect to the outstanding shares of capital
stock of Trimeris owned of record by the Stockholder as of the date of this proxy, which shares are specified on the final page of this proxy. (The shares of the capital stock of Trimeris referred to in the immediately preceding sentence are
referred to as the “Shares.”) Upon the execution of this proxy, all prior proxies given by Stockholder with respect to any of the Shares are hereby revoked, and Stockholder agrees that no subsequent proxies inconsistent with this
Proxy will be given with respect to any of the Shares. 
 This proxy is irrevocable, is coupled with an interest and is granted
in connection with, and as security for, the Voting Agreement, dated as of the date hereof, between Synageva and Stockholder (the “Voting Agreement”), and is granted in consideration of and as an inducement to Synageva entering into
the Agreement and Plan of Merger and Reorganization, dated as of the date hereof, among Synageva, Trimeris, and Tesla Merger Sub, Inc., a Delaware corporation (“Merger Sub”) and wholly-owned subsidiary of Trimeris (the
“Merger Agreement”), whereby Merger Sub will be merged with and into Synageva (the “Merger”). This proxy will terminate on the termination of the Voting Agreement in accordance with its terms. 

Prior to the termination of the Voting Agreement, the attorneys and proxies named above will be empowered, and may exercise this proxy,
to vote any Shares owned by Stockholder, at any meeting of the stockholders of Trimeris, however called, or at any adjournment or postponement thereof and on every action or approval by written consent of the stockholders of Trimeris: 

(i) in favor of the approval the Parent Charter Amendment, the issuance of shares of Parent Common Stock pursuant to the
Merger Agreement, and any actions required in furtherance thereof; 
 (ii) against any action or agreement that
would result in a breach in any material respect of any covenant, representation or warranty or any other obligation of Trimeris under the Merger Agreement; and 
 (iii) against (a) any Acquisition Proposal (as defined in the Merger Agreement) involving Trimeris or any of its subsidiaries, or (b) any action that is intended, or would reasonably be
expected, to impede, interfere with, prevent, delay, postpone or adversely affect the Merger or the transactions contemplated by the Merger Agreement. 
 Stockholder may vote the Shares on all other matters not referred to in this proxy, and the attorneys and proxies named above may not exercise this proxy with respect to such other matters. 

This proxy shall be binding upon the heirs, estate, executors, personal representatives,

 
successors and assigns of the Stockholder (including any transferee of any of the Shares). 
 Any term or provision of this proxy that is invalid or unenforceable in any situation in any jurisdiction shall not affect the validity or enforceability of the remaining terms and provisions of this
proxy or the validity or enforceability of the offending term or provision in any other situation or in any other jurisdiction. Upon such determination that any term or provision is invalid, illegal or incapable of being enforced, the parties hereto
shall negotiate in good faith to modify this proxy so as to effect the original intent of the parties as closely as possible in an acceptable manner to the end that the transactions contemplated hereby are fulfilled to the fullest extent possible.

 [Signature page follows] 

					
	Dated: June 13, 2011	 		 	STOCKHOLDER
			
	 	 		 	  
		 		 	Signature
			
	 	 		 	  
		 		 	Printed Name
			
		 		 	Number of shares of capital stock of Trimeris owned of record as of the date of this proxy:
			
		 		 	 
			
		 		 	Number of options to purchase capital stock of Parent owned of record as of the date of this proxy:

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