Document:

GOLDMAN SACHS & CO. 185 BROAD STREET  NEW YORK, NEW YORK 10004
TEL: 212-902-1000
                                                        Opening Transaction

To:       Techne Corporation
          614 McKinley Place N.E.
          Minneapolis. MN 55413

From:     Goldman, Sachs & Co.

Subject:  Accelerated Share Repurchase Transaction - VWAP Pricing
          (Collared and Non-Collared)

Ref. No:  EN50B4000000000

Date:     March 1, 2005

This master confirmation ("Master Confirmation") dated as of March 1, 2005, is
intended to supplement the terms and provisions of certain Transactions (each, a
"Transaction") entered into from time to time between Goldman, Sachs & Co.
("GS&Co.") and Techne Corporation ("Counterparty"). This Master Confirmation,
taken alone, is neither a commitment by either party 10 enter into any
Transaction nor evidence of a Transaction. The terms of any particular
Transaction shall be set forth in a Supplemental Confirmation in the form of
Annex A or Annex B hereto, as the case may be, which references this Master
Confirmation, in which event the terms and provisions of this Master
Confirmation shall be deemed to be incorporated into and made a part of each
such Supplemental Confirmation. This Master Confirmation and each Supplemental
Confirmation together shall constitute a "Confirmation" as referred to in the
Agreement specified below.

The definitions and provisions contained in the 2002 ISDA Equity Derivatives
Definitions (the "Equity Definitions"), as published by the International Swaps
and Derivatives Association, Inc., are incorporated into this Master
Confirmation. This Master Confirmation and each Supplemental Confirmation
evidences a complete binding agreement between the Counterparty and GS&Co. as to
the terms of each Transaction to which this Master Confirmation and the related
Supplemental Confirmation relates.

All provisions contained in or incorporated by reference in the form of the 1992
ISDA Master Agreement (Multi-Currency Cross Border) (the "ISDA Form" or the
"Agreement") will govern this Master Confirmation and each Supplemental
Confirmation except as expressly modified hereby or thereby. Subject to the
preceding sentence, this Master Confirmation and each Supplemental Confirmation,
together with all other documents referring to the Agreement confirming
Transactions entered into between GS&Co. and Counterparty, shall supplement,
form a part of, and be subject to the ISDA Form as if GS&Co. and Counterparty
had executed the Agreement (but without any Schedule except for (i) the election
of Loss and Second Method, New York law (without regard to the conflicts of law
principles) as the governing law and US Dollars ("USD") as the Termination
Currency, (ii) the election that subparagraph (ii) of Section 2(c) will not
apply to Transactions, (iii) the replacement of the word "third" in the last
line of Section 5(a)(i) with the word "first" and (iv) the election that the
"Cross Default" provisions of Section 5(a)(vi) shall apply to Counterparty, with
a "Threshold Amount" of USD 50 million).

All provisions contained in the Agreement shall govern this Master Confirmation
and the related Supplemental Confirmation relating to a Transaction except as
expressly modified below or in the related Supplemental Confirmation. With
respect to any relevant Transaction, the Agreement, this Master Confirmation and
the related Supplemental Confirmation, together with an other documents
referring to the Agreement confirming Transactions entered into between GS&Co.
and Counterparty, shall represent the entire agreement and understanding of the
parties with respect to the subject matter and terms of such Transaction and
shall supersede all prior or contemporaneous written or oral communications with
respect thereto.

If, in relation to any Transaction to which this Master Confirmation and related
Supplemental Confirmation relate, there is any inconsistency between the
Agreement, this Master Confirmation, any Supplemental Confirmation and the
Equity Definitions that are incorporated into any Supplemental Confirmation, the
following will prevail for purposes of such Transaction in the order of
precedence indicated: (i) such Supplemental Confirmation; (ii) this Master
Confirmation; (iii) the Agreement; and (iv) the Equity Definitions.

     l. Each Transaction constitutes a Share Forward Transaction for the
purposes of the Equity Definitions. Set forth below are the terms and conditions
which, together with the terms and conditions set forth in each Supplemental
Confirmation (in respect of each relevant Transaction), shall govern each such
Transaction.

General Terms:

   Trade Date:                    For each Transaction, as set forth in the
                                  Supplemental Confirmation.

   Seller:                        Counterparty

   Buyer:                         GS&Co.

   Shares:                        Common Stock (par value $0.01) of
                                  Counterparty
                                  (Ticker:TECH)

   Number of Shares:              For each Transaction. as set forth in the
                                  Supplemental Confirmation.

   Forward Price:                 For each Transaction, as set forth in the
                                  Supplemental Confirmation.

   Capped Settlement Amount:      For each Collared Transaction, as set
                                  forth in the Supplemental Confirmation.

   Floor Settlement Amount:       For each Collared Transaction, as set
                                  forth in the Supplemental Confirmation.

   Hedge Forward Differential:    For each Collared Transaction, as set forth
                                  in the Supplemental Confirmation.

   Hedge Forward
   Cash Settlement Amount:        For each Collared Transaction, as set forth
                                  in the Supplemental Confirmation.

   Collared Transaction:          A Transaction entered into pursuant to a
                                  Supplemental Confirmation in the form of
                                  Annex B hereto.

   Prepayment:                    Not Applicable

   Variable Obligation:           Not Applicable

   Exchange:                      NASDAQ

   Related Exchange(s):           All Exchanges

   Market Disruption Event:       The definition of "Market Disruption Event"
                                  in Section 6.3(a) of the Equity Definitions
                                  is hereby amended by inserting the words
                                  "at any time on any Scheduled Trading Day
                                  during the Valuation Period or" after the
                                  word "material," in the third line thereof.

   Counterparty Additional
   Payment Amount:                For each Transaction, as set forth in the
                                  Supplemental Confirmation, Counterparty
                                  shall pay the Counterparty Additional
                                  Payment Amount to GS&Co. on the Cash
                                  Settlement Payment Date.

Valuation:

   Valuation Period:              Each Scheduled Trading Day during the
                                  period commencing on and including the
                                  first succeeding Scheduled Trading Day
                                  following the Trade Date, or, for Collared
                                  Transactions, the first succeeding
                                  Scheduled Trading Day following the Hedge
                                  Completion Date (as defined in the
                                  Supplemental Confirmation), to and
                                  including the Valuation Date (but excluding
                                  any day(s) on which the Valuation Period is
                                  suspended in accordance with Section 5
                                  herein and including any day(s) by which
                                  the Valuation Period is extended pursuant
                                  to the provision below).

                                  Notwithstanding anything to the contrary in
                                  the Equity Definitions, to the extent that
                                  any Scheduled Trading Day in the Valuation
                                  Period is a Disrupted Day, the Valuation
                                  Date shall be postponed and the Calculation
                                  Agent in its sole discretion shall extend
                                  the Valuation Period and make adjustments
                                  to the weighting of each Relevant Price for
                                  purposes of determining the Settlement
                                  Price, with such adjustments based on,
                                  among other factors, the duration of any
                                  Market Disruption Event and the volume,
                                  historical trading patterns and price of
                                  the Shares. To the extent that there are
                                  9 consecutive Disrupted Days during the
                                  Valuation Period, then notwithstanding the
                                  occurrence of a Disrupted Day, the
                                  Calculation Agent shall have the option in
                                  its sole discretion to either determine the
                                  Relevant Price using its good faith
                                  estimate of the value for the Share on such
                                  9th consecutive day or elect to further
                                  extend the Valuation Period as it deems
                                  necessary.

   Valuation Date:                For each Transaction, as set forth in the
                                  Supplemental Confirmation (as the same may
                                  be postponed in accordance with the
                                  provisions of "Valuation Period" and
                                  Section 5 herein).

Settlement Terms:

   Settlement Currency:           USD (all amounts shall be converted to the
                                  Settlement Currency in good faith and in a
                                  commercially reasonable manner by the
                                  Calculation Agent).

   Settlement Method Election:    Applicable; provided that Section 7.1 of
                                  the Equity Definitions is hereby amended by
                                  deleting the word "Physical" in the sixth
                                  line thereof and replacing it with the
                                  words "Net Share" and deleting the word
                                  "Physical" in the last line thereof and
                                  replacing it with word "Cash".

   Electing Party:                Counterparty

   Settlement Method
   Election Date:                 20 Scheduled Trading Days prior to the
                                  originally scheduled Valuation Date.

   Default Settlement Method:     Cash Settlement

   Additional Cash Settlement
   Procedures:                    In addition to the payments payable
                                  pursuant to Section 8.4(a) of the Equity
                                  Definitions, the following additional
                                  amounts will be payable on the Cash
                                  Settlement Payment Date:

                                  (a) If the Collared Forward Cash
                                  Settlement Amount is a positive number,
                                  then Seller shall pay to Buyer the Collared
                                  Forward Cash Settlement Amount (such amount,
                                  the "Net Cash Amount"); or

                                  (b) if the Collared Forward Cash Settlement
                                  Amount is a negative number, then Buyer shall
                                  pay to Seller the absolute value of the
                                  Collared Forward Cash Settlement Amount.

   Collared Forward
   Cash Settlement Amount:        An amount in the Settlement Currency equal
                                  to the sum of the Hedge Forward Differential
                                  and:

                                  (a) if the Hedge Forward Cash Settlement
                                  Amount is a positive number, the lesser of
                                  the Hedge Forward Cash Settlement Amount and
                                  the Capped Settlement Amount; or

                                  (b) if the Hedge Forward Cash Settlement
                                  Amount is a negative number, the lesser of the
                                  absolute value of the Hedge Forward Cash
                                  Settlement Amount and the Floor Settlement
                                  Amount.

   Forward Cash
   Settlement Amount:             An amount in the Settlement Currency equal to
                                  the product of (a) the Number of Shares
                                  multiplied by one minus the Applicable
                                  Percentage, multiplied by (b) an amount equal
                                  to (i) the Settlement Price minus (ii) the
                                  Forward Price.

   Applicable Percentage:         For each Transaction, as set forth in the
                                  Supplemental Confirmation.

   Settlement Price:              The arithmetic mean of the Relevant Prices of
                                  the Shares for each Exchange Business Day in
                                  the Valuation Period.

   Relevant Price:                The NASDAQ Volume Weighted Average Price per
                                  share of the Shares for the regular trading
                                  session (including any extensions thereof) of
                                  the Exchange on the related Exchange
                                  Business Day (without regard to pre-open or
                                  after hours trading outside of such regular
                                  trading session) as published by Bloomberg at
                                  4: 15 p.m. New York time on such date. For
                                  purposes of calculating Relevant Price, the
                                  Calculation Agent will include only those
                                  trades which are reported during the period of
                                  time during which Counterparty could purchase
                                  its own shares under Rule I Ob-18(b )(2), and
                                  pursuant to the conditions of Rule I Ob-18
                                  (b )(3) and (b)( 4) each under the Exchange
                                  Act (as defined herein).

   Cash Settlement Payment Date:  3 Currency Business Days after the Valuation
                                  Date.

   Counterparty's Contact Details
   for Purpose of Giving Notice:   Gregory J. Melsen
                                   Techne Corporation
                                   Vice President Finance and Chief
                                   Financial Officer
                                   614 McKinley Place N.E.
                                   Minneapolis, MN 55413
                                   Telephone No.: (612) 656-4472
                                   Facsimile No.: (612) 379-6580

   GS&Co.' s Contact Details for
   Purpose of Giving Notice:       Telephone No.: (212) 902-8996
                                   Facsimile No.: (212) 902-0112
                                   Attention: Equity Operations: Options
                                              and Derivatives

                                   With a copy to:
                                   Kelly Coffey
                                   Equity Capital Markets
                                   One New York Plaza
                                   New York, NY 10004 Telephone
                                   No.: (212) 902-1037
                                   Facsimile No.: (212) 902-5305

Net Share Settlement:

   Net Share Settlement Procedures: Net Share Settlement shall be made in
                                    accordance with the procedures attached
                                    hereto as Annex C.

   Net Share Settlement Price:     (a) in respect of any Share for which the
                                   Exchange is an auction or "open outcry"
                                   exchange that has a price as of the
                                   Valuation Time at which any trade can be
                                   submitted for execution, the Net Share
                                   Settlement Price shall be the price per
                                   Share as of the Valuation Time on the Net
                                   Share Valuation Date as reported in the
                                   official real-time price dissemination
                                   mechanism for such Exchange, (b) in respect
                                   of any Share for which the Exchange is a
                                   dealer exchange or dealer quotation
                                   system, the Net Share Settlement Price shall
                                   be the mid-point of the highest bid and
                                   lowest ask prices quoted as of the Valuation
                                   Time on the Net Share Valuation Date (or the
                                   last such prices quoted immediately before
                                   the Valuation Time) without regard to
                                   quotations that "lock" or "cross" the dealer
                                   exchange or dealer quotation system. In an
                                   cases the Net Share Settlement Price shall be
                                   reduced by the per Share amount of the
                                   underwriting discount and/or commissions
                                   agreed to pursuant to the equity underwriting
                                   agreement contemplated by the Net Share
                                   Settlement Procedures and (c) notwith-
                                   standing anything to the contrary in (b)
                                   above, where NASDAQ is the Exchange, the
                                   Net Share Settlement Price will be the
                                   NASDAQ Official Closing Price (NOCP) as of
                                   the Valuation Time on the Net Share
                                   Valuation Date as reported in the official
                                   price determination mechanism for the
                                   Exchange.

   Valuation Time:                 As provided in Section 6.1 of the Equity
                                   Definitions; provided that Section 6.1 of the
                                   Equity Definitions is hereby amended by
                                   inserting the words "Net Share Valuation
                                   Date," before the words "Valuation Date" in
                                   the first and third lines thereof.

   Net Share Valuation Date:       The Exchange Business Day immediately
                                   following the Valuation Date.

   Net Share Settlement Date:      The third Exchange Business Day immediately
                                   following the Valuation Date.

   Reserved Shares:                For each Transaction) as set forth in the
                                   Supplemental Confirmation.

Share Adjustments:

   Method of Adjustment:           Calculation Agent Adjustment

Extraordinary Events:

Consequences of Merger Events:

   (a) Share-for-Share:            Modified Calculation Agent Adjustment

   (b) Share-for-Other:            Cancellation and Payment on that portion of
                                   the Other Consideration that consists of
                                   cash; Modified Calculation Agent Adjustment
                                   on the remainder of the Other Consideration.

   (c) Share-for-Combined:         Component Adjustment

   Determining Party:              GS&Co.

Tender Offer:                      Applicable

Consequences of Tender Offers:

   (a) Share-for-Share:            Modified Calculation Agent Adjustment

   (b) Share-for-Other:            Cancellation and Payment on that portion of
                                   the Other Consideration that consists of
                                   cash; Modified Calculation Agent Adjustment
                                   on the remainder of the Other Consideration.

   (c) Share-for-Combined:         Component Adjustment

   Determining Party:              GS&Co.

Nationalization, Insolvency
or Delisting:                      Negotiated Close-out; provided that in
                                   addition to the provisions of Section
                                   12.6(a)(iii) of the Equity Definitions, it
                                   shall also constitute a Delisting if the
                                   Exchange is located in the United States and
                                   the Shares are not immediately re-listed,
                                   re-traded or re-quoted on any of the New York
                                   Stock Exchange, the American Stock Exchange
                                   or The NASDAQ National Market (or their
                                   respective successors); if the Shares are
                                   immediately re-listed, re-traded or re-quoted
                                   on any such exchange or quotation system,
                                   such exchange or quotation system shall be
                                   deemed to be the Exchange.

Additional Disruption Events:

   (a) Change in Law:              Applicable

   (b) Failure to Deliver:         Not Applicable

   (c) Insolvency Filing:          Applicable

   (d) Loss of Stock Borrow:       Applicable; furthermore Sections 12.9(a)(vii)
                                   and 12.9(b)(iv) of the Equity Definitions are
                                   amended by deleting the words "at a rate
                                   equal to or less than the Maximum Stock Loan
                                   Rate" and replacing them with "at a rate of
                                   return equal to or greater than zero".

   Hedging Party:                  GS&Co.

   Determining Party:              GS&Co.

Non-Reliance:                      Applicable

Agreements and Acknowledgements
Regarding Hedging Activities:      Applicable

Additional Acknowledgements:       Applicable

Net Share Settlement following
Extraordinary Event:               Counterparty shall have the right, in its
                                   sole discretion, to make any payment required
                                   to be made by it pursuant to Sections 12.7 or
                                   12.9 of the Equity Definitions (except with
                                   respect to any portion of the consideration
                                   for the Shares consisting of cash in the
                                   event of a Merger Event or Tender Offer)
                                   following the occurrence of an Extraordinary
                                   Event by electing to Net Share Settle the
                                   Transactions under this Master Confirmation
                                   in accordance with the terms, and subject to
                                   the conditions, for Net Share Settlement
                                   herein by giving written notice to GS&Co. of
                                   such election on the day that the notice
                                   fixing the date that the Transactions are
                                   terminated or cancelled, as the case may be,
                                   (the "Cancellation Date") pursuant to the
                                   applicable provisions of Section 12 of the
                                   Equity Definitions is effective. If
                                   Counterparty elects Net Share Settlement:
                                   (a)the Net Share Valuation Date shall be the
                                   date specified in the notice fixing the date
                                   that the Transactions are terminated or
                                   cancelled, as the case may be; provided that
                                   the Net Share Valuation Date shall be either
                                   the Exchange Business Day that such notice is
                                   effective or the first Exchange Business Day
                                   immediately following the Exchange Business
                                   Day that such notice is effective, (b) the
                                   Net Share Settlement Date shall be deemed to
                                   be the Exchange Business Day immediately
                                   following the Cancellation Date and (c) a1l
                                   references to the Forward Cash Settlement
                                   Amount or the Net Cash Amount, as the case
                                   may be, in Annex C hereto shall be deemed to
                                   be references to the Cancellation Amount.

Net Share Settlement Upon
Early Termination:                 Counterparty shall have the right, in its
                                   sole discretion, to make any payment required
                                   to be made by it (the "Early Termination
                                   Amount") pursuant to Sections 6(d) and 6(e)
                                   of the Agreement following the occurrence of
                                   an Early Termination Date in respect of the
                                   Agreement by electing to Net Share Settle all
                                   the Transactions under this Master
                                   Confirmation in accordance with the terms,
                                   and subject to the conditions, for Net Share
                                   Settlement herein by giving written notice to
                                   GS&Co. of such election on the day that the
                                   notice fixing an Early Termination Date is
                                   effective. If Counterparty elects Net Share
                                   Settlement:  (a) the Net Share Valuation Date
                                   shall be the date specified in the notice
                                   fixing an Early Termination Date; provided
                                   that the Net Share Valuation Date shall be
                                   either the Exchange Business Day that such
                                   notice is effective or the first Exchange
                                   Business Day immediately following the
                                   Exchange Business Day that such notice is
                                   effective, (b) the Net Share Settlement
                                   Date shall be deemed to be the Exchange
                                   Business Day immediately following the Early
                                   Termination Date and (c) all references to
                                   Forward Cash Settlement Amount or the Net
                                   Cash Amount, as the case may be, in Annex C
                                   hereto shall be deemed references to the
                                   Early Termination Amount.

Transfer:                          Notwithstanding anything to the contrary in
                                   the Agreement, GS&Co. may assign, transfer
                                   and set over all rights, title and
                                   interest, powers, privileges and remedies of
                                   GS&Co. under any Transaction, in whole or in
                                   part, to an affiliate of GS&Co. that is
                                   guaranteed by The Goldman Sachs Group, Inc.
                                   without the consent of Counterparty.

GS&Co. Payment Instructions:       Chase Manhattan Bank New York
                                   For A/C Goldman, Sachs & Co.
                                   A/C #__________
                                   ABA: 021-000021

Counterparty Payment Instructions: To be provided by Counterparty

     2. Calculation Agent: GS&Co.

     3. Representations. Warranties and Covenants of GS&Co. and Counterparty.

(a) Each party represents and warrants that it (i) is an "eligible contract
participant", as defined in the U.S. Commodity Exchange Act, as amended and (ii)
is entering into each Transaction hereunder as principal (and not as agent or in
any other capacity, fiduciary or otherwise) and not for the benefit of any third
party.

(b) Each party acknowledges that the offer and sale of each Transaction to it is
intended to be exempt from registration under the Securities Act of 1933, as
amended (the "Securities Act"), by virtue of Section 4(2) thereof and the
provisions of Regulation D promulgated thereunder ("Regulation D"). Accordingly,
each party represents and warrants to the other that (i) it has the financial
ability to bear the economic risk of its investment in each Transaction and is
able to bear a total loss of its investment, (ii) it is an "accredited investor"
as that term is defined under Regulation D, (iii) it will purchase each
Transaction for investment and not with a view to the distribution or resale
thereof, and (iv) the disposition of each Transaction is restricted under this
Master Confirmation and each Supplemental Confirmation, the Securities Act and
state securities laws.

(c) Each party acknowledges that, for the avoidance of doubt, no collateral is
required to be posted by Counterparty with respect to any Transaction.

     4. Additional Representations. Warranties and Covenants of Counterparty.

As of (i) the date hereof and (ii) the period of time from and including the
time at which Counterparty places an order with GS&Co. for a Transaction (the
"Time of the Order") to and including the Hedge Completion Date, Counterparty
represents, warrants and covenants to GS&Co. that:

(a) Counterparty will provide notice to GS&Co. of any third-party tender offer
of which it is aware for purposes of Rule 13e-l under the Securities Exchange
Act of 1934, as amended (the "Exchange Act");

(b) is not entering into any Transaction on the basis of, and is not aware of,
any material nonpublic information with respect to the Shares or in anticipation
of, in connection with, or to facilitate, a distribution of its
securities, a self tender offer or a third-party tender offer;

(c) it is not entering into any Transaction to create, and will not engage in
any other securities or derivative transaction to create, a false or misleading
appearance of active trading or market activity in the Shares (or any security
convertible into or exchangeable for the Shares), or which would otherwise
violate the Exchange Act;

(d) Counterparty is in compliance with its reporting obligations under the
Exchange Act and its most recent Annual Report on Form IO-K, together with all
reports subsequently filed by it pursuant to the Exchange Act, taken together
and as amended and supplemented to the date of this representation, do not, as
of their respective filing dates, contain any untrue statement of a material
fact or omit any material fact required to be stated therein or necessary to
make the statements therein, in the light of the circumstances in which they
were made, not misleading;

(e) each Transaction is being entered into pursuant to a publicly disclosed
Share buy-back program and its Board of Directors has approved the Agreement and
the Master Confirmation (including the use of derivatives) in substantially the
form of such documents executed and delivered by the parties hereto to effect
the Share buy-back program;

(f) notwithstanding the generality of Section 13.1 of the Equity Definitions,
GS&Co. is not making any representations or warranties with respect to the
treatment of any Transaction under FASB Statements 149 or 150, EITF 00-19 (or
any successor issue statements) or under FASB's Liabilities & Equity Project;

(g) it will not take any action or refrain from taking any action that would
knowingly limit or in any way adversely affect GS&Co.'s rights under the
Agreement, so long as GS&Co. is not in breach of the Agreement or this Master
Confirmation, provided that the foregoing shall not in any manner be construed
to limit Counterparty's ability to protect, preserve and pursue any of its
rights under the Agreement or this Master Confirmation in a commercially
reasonable manner;

(h) it has not, and during any Valuation Period (as extended pursuant to the
provisions of Section 5 and "Valuation Period" herein) or Hedge Period will not,
enter into agreements similar to the Transactions described herein where the
valuation period in such other transaction will overlap at any time (including
as a result of extensions in such valuation period as provided in the relevant
agreements) with any Valuation Period (as extended pursuant to the provisions of
Section 5 and "Valuation Period" herein) or Hedge Period under this Master
Confirmation. In the event that the valuation period in any other similar
transaction overlaps with any Hedge Period or any Valuation Period under this
Master Confirmation as a result of any extension made pursuant to the provisions
of Section 5 and "Valuation Period" herein, Counterparty shall promptly amend
such transaction to avoid any such overlap;

(i) during the Hedge Period and the Valuation Period (as extended or
suspended pursuant to the provisions of Section 5 and "Valuation Period" herein)
the Shares or securities that are convertible into, or exchangeable or
exercisable for Shares are not subject to a "restricted period" as such term is
defined in Regulation M promulgated under the Exchange Act ("Regulation M");

(j) upon entering into each Transaction the Counterparty covenants that it wi1l
immediately retire or hold in treasury the Number of Shares purchased by it in
connection with the relevant Transaction from an entity affiliated with GS&Co.;
and

(k) it shall report each Transaction as required under Regulation S-K and/or
Regulation S-B under the Exchange Act, as applicable.

     5. Suspension of Valuation Period and/or Hedge Period.

(a) If Counterparty concludes that it will be engaged in a distribution of the
Shares for purposes of Regulation M, Counterparty agrees that it wi1t, on one
Scheduled Trading Day's written notice, direct GS&Co. not to purchase Shares in
connection with hedging any Transaction during the "restricted period" (as
defined in Regulation M). If on any Scheduled Trading Day Counterparty delivers
written notice (and confirms by telephone) by 8:30 a.m. New York Time (the
"Notification Time") then such notice shall be effective to suspend the
Valuation Period or the Hedge Period, as the case may be, as of such
Notification Time. In the event that Counterparty delivers notice and/or
confirms by telephone after the Notification Time, then the Valuation Period or
the Hedge Period, as the case may be, shall be suspended effective as of 8:30
a.m. New York Time on the following Scheduled Trading Day or as otherwise
required by law or agreed between Counterparty and GS&Co. The Valuation Period
shall be suspended and the Valuation Date extended for each Scheduled Trading
Day in such restricted period.

(b) In the event that GS&Co. concludes, in its sole discretion, that it is
appropriate with respect to any legal, regulatory or self-regulatory
requirements or related policies and procedures (whether or not such
requirements, policies or procedures are imposed by law or have been voluntarily
adopted by GS&Co.), for it to refrain from purchasing Shares on any Scheduled
Trading Day during the Valuation Period or the Hedge Period, GS&Co. may by
written notice to Counterparty elect to suspend the Valuation Period or the
Hedge Period, as the case may be, for such number of Scheduled Trading Days as
is specified in the notice. The notice shall not specify, and GS&Co. shall not
otherwise communicate to Counterparty, the reason for GS&Co. 's election to
suspend the Valuation Period or the Hedge Period. The Valuation Period shall be
suspended and the Valuation Date extended for each Scheduled Trading Day
occurring during any such suspension.

(c) On one occasion and upon written notice to GS&Co. prior to 8:30 a.m. New
York time on any Scheduled Trading Day during the Valuation Period and the Hedge
Period, Counterparty may elect to suspend the Valuation Period or the Hedge
Period, as the case may be, for such number of Scheduled Trading Days as is
specified in the notice up to a maximum of 30 calendar days. The notice shall
not specify, and Counterparty shall not otherwise communicate to GS&Co., the
reason for Counterparty's election to suspend the Valuation Period or the Hedge
Period. The Valuation Period shall be suspended and the Valuation Date extended
for each Scheduled Trading Day occurring during any such suspension.

(d) In the event Counterparty is subject to a third-party tender offer, and for
purposes of Counterparty's compliance with Rule Be-I, Counterparty may elect,
upon written notice to GS&Co. prior to 8:30 a.m. New York time on any Scheduled
Trading Day during the Valuation Period and the Hedge Period, to suspend the
Valuation Period or the Hedge Period, as the case may be, for such number of
Scheduled Trading Days as is specified in the notice up to a maximum of 30
calendar days. The Valuation Period shall be suspended and the Valuation Date
extended for each Scheduled Trading Day occurring during any such suspension.

(e) In the event that the Valuation Period is suspended pursuant to Sections
5(a),(b), (c) or (d) above during the regular trading session on the Exchange
then the Calculation Agent in its sole discretion shall, in calculating the
Forward Cash Settlement Amount, extend the Valuation Period and make adjustments
to the weighting of each Relevant Price for purposes of determining the
Settlement Price, with such adjustments based on, among other factors, the
duration of any such suspension and the volume, historical trading patterns and
price of the Shares.

      6. Counterparty Purchases. Counterparty represents, warrants and covenants
to GS&Co. that for each Transaction:

(a) Counterparty (or any "affiliated purchaser" as defined in Rule 1 Ob-18 under
the Exchange Act ("Rule 10b-18") shall not, without the prior written consent
of GS&Co., purchase any Shares, listed contracts on the Shares or securities
that are convertible into, or exchangeable or exercisable for Shares (including,
without limitation, any Rule IOb-18 purchases of blocks (as defined in Rule I
Ob-18)) during any Valuation Period or Hedge Period (as extended pursuant to the
provisions of Section 5 and "Valuation Period" herein). During this time, any
such purchases by Counterparty shall be made through GS&Co., or if not through
GS&Co., with the prior written consent of GS&Co., and in compliance with Rule
lOb-18 or otherwise in a manner that Counterparty and GS&Co. believe is in
compliance with applicable requirements. Any such purchase by Counterparty shall
be disregarded for purposes of determining the Forward Cash Settlement Amount.
To the extent that Counterparty makes any such purchase other than through
GS&Co., or other than in connection with any Transaction, Counterparty hereby
represents and warrants to GS&Co. that (a) it will not take other action that
would or could cause GS&Co.'s purchases of the Shares during the Valuation
Period and the Hedge Period not to comply with Rule 1Ob-18 and (b) any such
purchases will not otherwise constitute a violation of Section 9(a) or Rule
10(b) of the Exchange Act. This subparagraph (a) shall not restrict any
purchases by Counterparty of Shares effected during any suspension of any
Valuation Period or any Hedge Period in accordance with Section 5 herein and any
purchases during such suspension shall be disregarded in calculating the Forward
Cash Settlement Amount; and

(b) Counterparty is entering into this Master Confirmation and each Transaction
hereunder in good faith and not as part of a plan or scheme to evade the
prohibitions of Rule 1Ob5-1 under the Exchange Act ("Rule 10b5-1 "). It is the
intent of the parties that each Transaction entered into under this Master
Confirmation comply with the requirements of Rule lOb5-l(c)(1)(i)(A) and (B) and
each Transaction entered into under this Master Confirmation shall be
interpreted to comply with the requirements of Rule 1Ob5-l(c). Counterparty wi1l
not seek to control or influence GS&Co. to make "purchases or sales" (within the
meaning of Rule 1Ob5-1(c)(l)(i)(B)(3)) under any Transaction entered into under
this Master Confirmation, including, without limitation, GS&Co.'s decision to
enter into any hedging transactions. Counterparty represents and warrants that
it has consulted with its own advisors as to the legal aspects of its adoption
and implementation of this Master Confirmation and each Supplemental
Confirmation under Rule 1Ob5-1.

     7. Additional Termination Events. Additional Termination Event will apply.
The following will constitute Additional Termination Events, in each case with
Counterparty as the sole Affected Party:

(a) Notwithstanding anything to the contrary in the Equity Definitions, the
occurrence of a Nationalization, Insolvency or a Delisting (in each case
effective on the Announcement Date as determined by the Calculation Agent);

(b) Notwithstanding anything to the contrary in the Equity Definitions, the
occurrence of a Merger Event (effective on the Merger Date) or a Tender Offer
(effective on the Tender Offer Date) in respect of which any Other Consideration
received for the Shares does not consist of cash. For the avoidance of doubt, in
the event that any portion of the consideration received for the Shares consists
of cash or New Shares, this Additional Termination Event shall only apply with
respect to all or any Transaction(s) (or portions thereof) remaining after
giving effect to the provisions in "Consequences of Merger Events" or
"Consequences of Tender Offers", as the case may be, above;

(c) GS&Co. shall reasonably believe in good faith that Counterparty will be
unable to meet its obligations when due for any reason and Counterparty fails,
after 10 Business Days prior written notice from GS&Co. to provide GS&Co. with
reasonable assurance of its ability to perform: or

(d) Notwithstanding anything to the contrary in the Equity Definitions, an
Extraordinary Dividend is declared by the Issuer.

     8. Additional Event of Default. The following will constitute an Event of
Default for purposes of Section 5(a) of the Agreement (with Counterparty
considered to be the Defaulting Party as a result of clause (a) and Counterparty
or GS&Co. considered to be the Defaulting Party as a result of clause (b), as
the case may be):

(a) Counterparty fails to perform any material obligation required to be
performed under any other agreement between Counterparty and GS&Co. or its
affiliated entities (after giving effect to any applicable notice requirement or
grace period, or such default continues for at least three Exchange Business
Days if there is no applicable notice requirement or grace period).

(b) Counterparty reasonably believes in good faith that continued performance of
the Agreement by either party would contravene any law, regulation or order (or
similar obligation to which it is subject) (such party shall be
the Defaulting Party) or that GS&Co. has failed to comply with any federal or
state securities laws or regulations or any applicable regulations of self-
regulatory organizations of which it is a member in the performance of its
obligations under the Agreement.

     9. Automatic Termination Provisions. Notwithstanding anything to the
contrary in Section 6 of the Agreement:

(a) An Additional Termination Event with Counterparty as the sole Affected Party
will automatically occur without any notice or action by GS&Co. or Counterparty
if the price of the Shares on the Exchange at any time fans below the
Termination Price (as specified in the related Supplemental Confirmation)
provided that (for the avoidance of doubt only) such Additional Termination
Event shall be an Additional Termination Event only with respect to the
Transaction documented in such related Supplemental Confirmation. The Exchange
Business Day that the price of the Shares on the Exchange at any time falls
below the Termination Price will be the "Early Termination Date" for purposes of
the Agreement.

(b) Notwithstanding anything to the contrary in Section 6(d) of the Agreement.
fol1owing the occurrence of such an Additional Termination Event, GS&Co. will
notify Counterparty of the amount owing under Section 6(e) of the Agreement
within a commercially reasonable time period (with such period based upon the
amount of time, determined by GS&Co. (or any of its Affiliates) in its sole
discretion, that it would take to unwind any of its Hedge Position(s) related to
the Transaction in a commercially reasonable manner based on relevant market
indicia). For purposes of the "Net Share Settlement Upon Early Termination"
provisions herein, (i) the date that such notice is effective (the "Notice
Date") shall constitute the "Net Share Valuation Date", (ii) the Exchange
Business Day immediately following the Notice Date shall be the Net Share
Settlement Date and (iii) all references to the Net Cash Amount in Annex C
hereto shall be deemed to be the Early Termination Amount.

     10. Special Provisions for Merger Events. Notwithstanding anything to the
contrary herein or in the Equity Definitions, to the extent that an Announcement
Date for a potential Merger Transaction occurs during any Valuation Period:

(a) Promptly after request from GS&Co., Counterparty shall provide GS&Co. with
written notice specifying (i) Counterparty's average daily Rule 1Ob-18 Purchases
(as defined in Rule lOb-18) during the three full calendar months immediately
preceding the Announcement Date that were not effected through GS&Co. or its
affiliates and (ii) the number of Shares purchased pursuant to the proviso in
Rule 1Ob-18(b)(4) under the Exchange Act for the three full calendar months
preceding the Announcement Date. Such written notice shall be deemed to be a
certification by Counterparty to GS&Co. that such information is true and
correct. Counterparty understands that GS&Co. will use this information in
calculating the trading volume for purposes of Rule 1Ob-18; and

(b) GS&Co. in its sole discretion may (i) make adjustments to the terms
of any Transaction, including, without limitation, the Valuation Date, the
Counterparty Additional Payment Amount and the Number of Shares to account for
the number of Shares that could be purchased on each day during the Valuation
Period in compliance with Rule 1Ob-18 following the Announcement Date or (ii)
treat the occurrence of the Announcement Date as an Additional Termination Event
with Counterparty as the sole Affected Party.

"Merger Transaction" means any merger, acquisition or similar transaction
involving a recapitalization as contemplated by Rule IOb-18(a)(l3)(iv) under the
Exchange Act.

     11. Special Calculation and Settlement Following Early Termination and
Extraordinary Events. Notwithstanding anything to the contrary in this Master
Confirmation or any Supplemental Confirmation hereunder, in the event that an
Extraordinary Event under Article 12 of the Equity Definitions occurs or an
Early Termination Date occurs or is designated with respect to any Transaction
(each an "Affected Transaction"), then GS&Co. may elect, in its sole discretion,
by notice to Counterparty, to have Counterparty deliver the Number of Early
Settlement Shares to GS&Co. on the date that such notice is effective and either
GS&Co. shall pay to Counterparty the Special Termination Amount, if positive, or
Counterparty shall pay to GS&Co. the absolute value of the Special Termination
Amount, if negative. To the extent that Counterparty elects to deliver Shares to
GS&Co. accompanied by an effective Registration Statement (satisfactory to
GS&Co. in its sole discretion) covering such Shares, Counterparty must be in
compliance with the conditions specified in (iii) though (ix) in Annex C hereto
at the time of such delivery. If Counterparty elects to deliver Unregistered
Shares (as defined in Annex C) to GS&Co., Counterparty and GS&Co. will negotiate
in good faith on acceptable procedures and documentation relating to the
sale of such Unregistered Shares. Counterparty and GS&Co. agree that the payment
of the Special Termination Amount and the delivery of the Number of Early
Settlement Shares satisfies in full any obligation of a party to make
any payments pursuant to Section 6(e) of the Agreement or Article 12 of the
Equity Definitions. as the case may be.

"Number of Early Settlement Shares" means a number of Shares as determined by
GS&Co. in a good faith and commercially reasonable manner based on its or any of
its Affiliates' Hedge Positions with respect to each Affected Transaction under
this Master Confirmation.

"Special Termination Amount" means, without duplication, the sum of (a) the
product of (i) the Number of Early Settlement Shares multiplied by (ii) a per
Share price (the "Early Termination Price") determined by GS&Co. in a good faith
and commercially reasonable manner based on relevant market indicia, including
GS&Co.'s funding costs associated with Early Settlement Shares and costs
incurred or estimated to be incurred by GS&Co. in connection with the purchase
and sale of Shares in order to close out GS&Co.'s or any of its Affiliates'
Hedge Positions with respect to each Affected Transaction and, in the event that
Counterparty delivers Unregistered Shares to GS&Co., whether GS&Co. and
Counterparty have agreed on acceptable procedures and documentation relating to
such Unregistered Shares as described above and (b) any amount owing under
Section 6(e) of the Agreement or pursuant to Article 12 of the Equity
Definitions, as the case may be, by GS&Co. to Counterparty (expressed as a
positive number) or by Counterparty to GS&Co. (expressed as a negative number).

     12. Acknowledgments. The parties hereto intend for:

(a) Each Transaction to be a "securities contract" as defined in Section 741
(7) of the U.S. Bankruptcy Code (Title II of the United States Code) (the
"Bankruptcy Code"), a "swap agreement" as defined in Section 101(53B) of the
Bankruptcy Code, or a "forward contract" as defined in Section 101(25) of the
Bankruptcy Code, and the parties hereto to be entitled to the protections
afforded by, among other Sections, Sections 362(b)(6), 362(b)(17),555, 556, and
560 of the Bankruptcy Code;

(b) A party's right to liquidate or terminate any Transaction, net out
or offset termination values of payment amounts, and to exercise any other
remedies upon the  occurrence of any Event of Default under the Agreement with
respect to the other party to constitute a "contractual right" (as defined in
the Bankruptcy Code);

(c) Any cash, securities or other property transferred as performance assurance,
credit support or col1ateral with respect to each Transaction to constitute
"margin payments" (as defined in the Bankruptcy Code);

(d) All payments for, under or in connection with each Transaction, an payments
for the Shares and the transfer of such Shares to constitute "settlement
payments" and "transfers" (as defined in the Bankruptcy
Code); and

(e) GS&Co. to not have any rights that rank higher than those rights held by
shareholders of Shares.

     13. Calculations on Early Termination and Set-Off.

(a) Notwithstanding anything to the contrary in the Agreement or the Equity
Definitions, the calculation of any Settlement Amounts, Unpaid Amounts and
amounts owed in respect of cancelled Transactions under Article 12 of the Equity
Definitions shall be calculated separately for (A) all Terminated Transactions
(it being understood that such term for the purposes of this paragraph includes
cancelled Transactions under Article 12 of the Equity Definitions) in the Shares
of the Issuer that qualify as equity under applicable accounting rules
(collectively, the "Equity Shares") as determined by the Calculation Agent and
(B) all other Terminated Transactions under the Agreement including, without
limitation, Transactions in Shares other than those of the Issuer (collectively,
the "Other Shares") and the netting and set-off provisions of the Agreement
shall only operate to provide netting and set-off (i) among Terminated
Transactions in the Equity Shares and (ii) among Terminated Transactions in the
Other Shares. In no event shall the netting and set-off provisions of the
Agreement operate to permit netting and set-off between Terminated Transactions
in the Equity Shares and Terminated Transactions in the Other Shares.

(b) The parties agree to amend Section 6 of the Agreement by adding a new
Section 6(f) thereto as follows:

"(f) Upon the occurrence of an Event of Default or Termination Event with
respect to a party who is the Defaulting Party or the Affected Party ("X"), the
other party ("V") will have the right (but not be obliged) without prior notice
to X or any other person to set-off or apply any obligation of X owed to Y (or
any Affiliate of Y) (whether or not matured and whether or not arising under the
Agreement, and regardless of the currency, place of payment or booking office
of the obligation) against any obligation of Y (or any Affiliate of Y) owed to X
(whether or not matured and whether or not arising under the Agreement, and
regardless of the currency, place of payment or booking office of the
obligation).  Y will give notice to the other party of any set-off effected
under this Section 6(f).

Amounts (or the relevant portion of such amounts) subject to set-off may be
converted by Y into the Termination Currency at the rate of exchange at which
such party would be able, acting in a reasonable manner and in good faith, to
purchase the relevant amount of such currency.  If any obligation is
unascertained, Y may in good faith estimate that obligation and set-off in
respect of the estimate, subject to the relevant party accounting to the other
when the obligation is ascertained. Nothing in this Section 6(f) shall be
effective to create a charge or other security interest. This Section 6(f) shall
be without prejudice and in addition to any right of set-off, combination of
accounts, lien or other right to which any party is at any time otherwise
entitled (whether by operation of law, contract or otherwise)."

     14. Payment Date Upon Early Termination. Notwithstanding anything to the
contrary in Section 6(d)(ii) of the Agreement, all amounts calculated as being
due in respect of an Early Termination Date under Section 6(e) of the Agreement
will be payable on the day that notice of the amount payable is effective.

     15. Governing Law. The Agreement, this Master Confirmation and each
Supplemental Confirmation and all matters arising in connection with the
Agreement. this Master Confirmation and each Supplemental Confirmation shall be
governed by, and construed and enforced in accordance with, the law of the
State of New York without reference to its choice of law doctrine.

     16. Offices.

(a) The Office of GS&Co. for each Transaction is: One New York Plaza, New York,
New York 10004.

(b) The Office of Counterparty for each Transaction is: 6]4 McKinley Place N.E.,
Minneapolis, Minnesota 55413.

     17. Arbitration.

(a) Arbitration is final and binding on Counterparty and GS&Co.

(b) Counterparty and GS&Co. are waiving their right to seek remedies in court,
including the right to a jury trial.

(c) Pre-arbitration discovery is generally more limited than and different from
court proceedings.

(d) The arbitrator's award is not required to include factual findings or legal
reasoning and any party's right to appeal or to seek modification of rulings by
the arbitrators is strictly limited.

(e) The panel of arbitrators will typically include a minority of arbitrators
who were or are affiliated with the securities industry.

Any controversy between or among GS&Co. or its affiliates, or any of its or
their partners, directors, agents or employees, on the one hand, and
Counterparty or its agents and affiliates, on the other hand, arising out of or
relating to the Agreement or any Transaction entered into hereunder, shall be
settled by arbitration, in accordance with the then current rules of, at
Counterparty's election, the American Arbitration Association ("AAA") or the
Board of Arbitration of the New York Stock Exchange, Inc. ("BANYSE"). If
Counterparty does not make such election by registered mail addressed to GS&Co.
within five (5) Exchange Business Days after receipt of notification from GS&Co.
requesting such election, then Counterparty irrevocably authorizes GS&Co. to
make such election on behalf of Counterparty. The award of the arbitrators shall
be final, and judgment upon the award rendered may be entered in any court,
state or Federal, having jurisdiction.

Neither party shall bring a putative or certified class action to arbitration,
nor seek to enforce any pre-dispute arbitration agreement against any person who
has initiated in court a putative class action; who is a member of a putative
class who has not opted out of the class with respect to any claims encompassed
by the putative class action until:

(i) the class certification is denied;

(ii) the class is decertified; or

(iii) the party is excluded from the class by the court.

Such forbearance to enforce an agreement to arbitrate shall not constitute a
waiver of any rights under the Agreement except to the extent stated herein.

     18. Counterparty hereby agrees (a) to check this Master Confirmation
carefully and immediately upon receipt so that errors or discrepancies can be
promptly identified and rectified and (b) to confirm that the foregoing (in the
exact form provided by GS&Co.) correctly sets forth the terms of the agreement
between GS&Co. and Counterparty with respect to any Transaction., by manually
signing this Master Confirmation or this page hereof as evidence of agreement to
such terms and providing the other information requested herein and immediately
returning an executed copy to Equity Derivatives Documentation Department,
facsimile No. 212-428-1980/83.

                                       Yours sincerely,

                                       GOLDMAN, SACHS & CO.

                                        By:______________________
                                           Authorized Signatory

Agreed and Accepted By:
TECHNE CORPORATION

By: _______________________
    Name
    Title
..

                                  ANNEX A

              SUPPLEMENTAL CONFIRMATION FOR FULLY UNCOLLARED TRANSACTIONS

To:       Techne Corporation
          614 McKinley Place N.E.
          Minneapolis, MN 55413

From:     Goldman, Sachs & Co.

Subject:  Accelerated Share Repurchase Transaction - VWAP Pricing

Ref. No:  [Insert Reference No.]

Date:     [Insert Date]

The purpose of this Supplemental Confirmation is to confirm the terms and
conditions of the Transaction entered into between Goldman, Sachs & Co.
("GS&Co.") and Techne Corporation ("Counterparty") (together, the "Contracting
Parties") on the Trade Date specified below. This Supplemental Confirmation is a
binding contract between GS&Co. and Counterparty as of the relevant Trade Date
for the Transaction referenced below.

The definitions and provisions contained in the Master Confirmation specified
below are incorporated into this Supplemental Confirmation. In the event of any
inconsistency between those definitions and provisions and this Supplemental
Confirmation, this Supplemental Confirmation will govern.

1.	This Supplemental Confirmation supplements, forms part of, and is subject
to the Master Confirmation dated as of March 1, 2005 (the "Master Confirmation")
between the Contracting Parties, as amended and supplemented from time to time.
All provisions contained in the Master Confirmation govern this Supplemental
Confirmation except as expressly modified below.

2. The terms of the Transaction to which this Supplemental Confirmation relates
are as follows:

Trade Date:                        [  ], 2005. In a related transaction
                                   Counterparty agreed to purchase a number of
                                   Shares equal to the Number of Shares from
                                   GS&Co. on the Trade Date at the Forward Price
                                   per Share.

Forward Price:                     USD [ ] per Share

Valuation Date:                    [      ], 2005 (1)

Number of Shares:                  [       ] Shares

Termination Price:                 $15.00 per Share

Reserved Shares:                   6,000,000 Shares

(1) [ ] month(s) after the Trade Date.

3.  Counterparty represents and warrants to GS&Co. that neither it (nor any
"affiliated purchaser" as defined in Rule 1Ob-18 under the Exchange Act) have
made any purchases of blocks pursuant to the proviso in Rule 10b-18(b)(4) under
the Exchange Act during the four full calendar weeks immediately preceding the
Trade Date.

Counterparty hereby agrees (a) to check this Supplemental Confirmation carefully
and immediately upon receipt so that errors or discrepancies can be promptly
identified and rectified and (b) to confirm that the foregoing (in the exact
form provided by GS&Co.) correctly sets forth the terms of the agreement between
GS&Co. and Counterparty with respect to this Transaction, by manually signing
this Supplemental Confirmation or this page hereof as evidence of agreement to
such terms and providing the other information requested herein and immediately
returning an executed copy to Equity Derivatives Documentation Department,
facsimile No. 212-428-1980/83.

                                                Yours sincerely,

                                                GOLDMAN, SACHS & CO.

                                                By:__________________

                                                Authorized Signatory
Agreed and Accepted
By: TECHNE CORPORATION

By:____________________
Name:
Title:

                                  ANNEX B

                 SUPPLEMENTAL CONFIRMATION FOR COLLARED TRANSACTIONS

To:       Techne Corporation
          614 McKinley Place N.E.
          Minneapolis, MN 55413

From:     Goldman, Sachs & Co.

Subject:  Collared Accelerated Share Repurchase Transaction - VWAP Pricing

Ref. No:  EN50B4000000000

Date:     March 1, 2005

The purpose of this Supplemental Confirmation is to confirm the terms and
conditions of the Transaction (the "Transaction") entered into between Goldman,
Sachs & Co. ("GS&Co.") and Techne Corporation ("Counterparty") (together, the
"Contracting Parties") on the Trade Date specified below. This Supplemental
Confirmation is a binding contract between GS&Co. and Counterparty as of the
relevant Trade Date for the Transaction referenced below. The final terms of the
Transaction shall be sent to Counterparty by GS&Co. substantially in the form of
a Trade Notification attached hereto as Schedule A.

The definitions and provisions contained in the Master Confirmation specified
below are incorporated into this Supplemental Confirmation. In the event of any
inconsistency between those definitions and provisions and this Supplemental
Confirmation, this Supplemental Confirmation will govern. This Transaction
constitutes a "Collared Transaction" for purposes of the Master Confirmation.

1.  This Supplemental Confirmation supplements, forms part of, and is subject
to the Master Confirmation dated as of March 1, 2005 (the "Master Confirmation")
between the Contracting Parties, as amended and supplemented from time to time.
All provisions contained in the Master Confirmation govern this Supplemental
Confirmation except as expressly modified below.

2. The terms of the Transaction to which this Supplemental Confirmation relates
are as follows:

Trade Date:                      As specified in the Trade Notification. In a
                                 related transaction Counterparty agreed to
                                 purchase a number of Shares equal to the
                                 Number of Shares from GS&Co. on the Trade Date
                                 at the Forward Price per Share.

Capped Settlement Amount:        The product of (a) 0.0% of the Hedge Period
                                 Market Price multiplied by (b) the Number of
                                 Shares multiplied by (c) the Applicable
                                 Percentage.

Floor Settlement Amount:         The product of (a) 5.5% of the Hedge Period
                                 Market Price multiplied by (b) the Number of
                                 Shares multiplied by (c) the Applicable
                                 Percentage.

Hedge Completion Date:           The Scheduled Trading Day on which GS&Co.
                                 finishes establishing its Hedge Positions, as
                                 determined by GS&Co. in its sole discretion.

Forward Price:                   USD $34.45 per Share

Hedge Period Market Price:       The NASDAQ Volume Weighted Average Price per
                                 share of the Shares over the Hedge Period
                                 (without regard to pre-open or after hours
                                 trading outside of regular trading sessions),
                                 as published by Bloomberg. For purposes of
                                 calculating the Hedge Period Market Price, the
                                 Calculation Agent will include only those
                                 trades which are reported during the period of
                                 time during which Counterparty could purchase
                                 its own shares under Rule 1Ob-18(b)(2), and
                                 pursuant to the conditions of Rule 1Ob-
                                 18(b)(3) and (b)(4) each under the Exchange
                                 Act.

Hedge Forward Differential:      The product of (a) the difference between the
                                 Hedge Period Market Price minus the Forward
                                 Price multiplied by the product of (b) the
                                 Number of Shares multiplied by (c) the
                                 Applicable Percentage.

Hedge Forward Cash
Settlement Amount:               The product of (a) the difference between the
                                 Settlement Price minus the Hedge Period Market
                                 Price multiplied by the product of (b) the
                                 Number of Shares multiplied by (c) the
                                 Applicable Percentage.

Hedge Period:                    The number of Scheduled Trading Days from and
                                 including the Time of the Order to and
                                 including the Scheduled Trading Day upon which
                                 GS&Co. fully establishes its Hedge Positions.

Initial Payment Amount:          An amount in USD equal to the product of (i)
                                 5.0% multiplied by (ii) (Number of Shares x
                                 Forward Price) multiplied by (iii) the
                                 Applicable Percentage, payable by Counterparty
                                 to GS&Co. by 10:00 a.m. New York time on the
                                 Scheduled Trading Day immediately following the
                                 Trade Date.

Valuation Date:                  As specified in the Trade Notification.

Number of Shares:                2,902,758 Shares

Applicable Percentage:           As specified in the Trade Notification.

Reserved Shares:                 6,000,000 Shares

Termination Price:               $15.00 per Share

Counterparty Additional
Payment Amount:                   As specified in the Trade Notification.

3.  Counterparty represents and warrants to GS&Co. that neither it (nor any
"affiliated purchaser" as defined in Rule 10b-18 under the Exchange Act) have
made any purchases of blocks pursuant to the proviso in Rule 1Ob-18(b)(4) under
the Exchange Act during the four full calendar weeks immediately preceding the
Trade Date.

[SIGNATURE PAGE FOLLOWS]

Counterparty hereby agrees (a) to check this Supplemental Confirmation carefully
and immediately upon receipt so that errors or discrepancies can be promptly
identified and rectified and (b) to confirm that the foregoing (in the exact
form provided by GS&Co.) correctly sets forth the terms of the agreement between
GS&Co. and Counterparty with respect to this Transaction by manually signing
this Supplemental Confirmation or this page hereof as evidence of Agreement to
such terms and providing the other information requested herein and immediately
returning an executed copy to Equity Derivatives Documentation Department,
facsimile No.212-428-1980/83.

                                          Yours sincerely,
                                          GOLDMAN, SACHS & CO.

                                          By:___________________________
                                          Authorized Signatory
Agreed and Accepted
By: TECHNE CORPORATION
By. ____________________
Name:
Title:

                                 SCHEDULE A

                 TRADE NOTIFICATION FOR COLLARED TRANSACTIONS

To: Techne Corporation
    614 McKinley Place N.E.
    Minneapolis, MN 55413

From: Goldman, Sachs & Co.

Subject: Collared Accelerated Share Repurchase Transaction-VWAP
         Pricing

Ref. No: EN50B4000000000

Date:  March 24,2005

The purpose of this Trade Notification is to notify you of certain terms in the
Transaction entered into between Goldman, Sachs & Co. ("GS&Co.") and Techne
Corporation ("Counterparty") (together, the "Contracting Parties") on the Trade
Date specified below.

The definitions and provisions contained in the Supplemental Confirmation
specified below are incorporated into this Trade Notification. In the event of
any inconsistency between those definitions and provisions and this Trade
Notification, this Trade Notification will govern.

This Trade Notification supplements, forms part of, and is subject to the
Supplemental Confirmation dated as of March 1, 2005 (the "Supplemental
Confirmation") between the Contracting Parties, as amended and supplemented from
time to time. All provisions contained in the Supplemental Confirmation govern
this Trade Notification.

The Supplemental Confirmation specified a method or formula for determining the
amounts, dates or numbers below. The actual amounts, dates or numbers are as
follows:

Trade Date:                             March 1, 2005

Hedge Completion Date:                  March 24, 2005

Capped Settlement Amount:               USD $0.00

Floor Settlement Amount:                USD $3,854,453.04

Hedge Forward Differential:             USD $8,529,761.82

Initial Payment Amount:                 USD $3,500,000.00

Counterparty Additional Payment Amount: USD $0.00

Valuation Date:                         December 23, 2005

Applicable Percentage:                  61.475%

                                Yours sincerely,
                                GOLDMAN, SACHS & CO.

                                By: ______________________
                                 Authorized Signatory

                                  ANNEX C

                      NET SHARE SETTLEMENT PROCEDURES

The following Net Share Settlement Procedures shall apply to the extent that
Counterparty elects Net Share Settlement in accordance with the Master
Confirmation:

Net Share Settlement shall be made by delivery of the number of Shares equal in
value to the Forward Cash Settlement Amount plus any Net Cash Amount, if
applicable (the "Settlement Shares"), with such Shares' value based on the Net
Share Settlement Price. Delivery of such Settlement Shares shall be made free of
any contractual or other restrictions in good transferable form on the Net Share
Settlement Date with Counterparty (i) representing and warranting to GS&Co. at
the time of such delivery that it has good, valid and marketable title or
right to sell and transfer all such Shares to GS&Co. under the terms of the
related Transaction free of any lien charge, claim or other encumbrance and (ii)
making the representations and agreements contained in Section 9.11 (ii) through
(iv) of the Equity Definitions to GS&Co. with respect to the Settlement Shares.
GS&Co. or any affiliate of GS&Co. designated by GS&Co. (GS&Co. or such
affiliate, "GS") shall resell the Settlement Shares during a period (the "Resale
Period") commencing no earlier than the Net Share Valuation Date. The Resale
Period shall end on the Exchange Business Day on which GS completes the sale of
all Settlement Shares or a sufficient number of Settlement Shares so that the
realized net proceeds of such sales exceed the Forward Cash Settlement Amount,
plus the Net Cash Amount if applicable. Notwithstanding the foregoing, if resale
by GS of the Settlement Shares, as determined by as in its sole discretion (i)
occurs during a distribution for purposes of Regulation M, and if as would be
subject to the restrictions of Rule 101 of Regulation M in connection with such
distribution, the Resale Period will be postponed or tolled, as the case may be,
until the Exchange Business Day immediately following the end of any "restricted
period" as such term is defined in Regulation M with respect to such
distribution under Regulation M or (ii) conflicts with any legal, regulatory or
self-regulatory requirements or related policies and procedures applicable to as
(whether or not such requirements, policies or procedures are imposed by law or
have been voluntarily adopted by GS), the Resale Period will be postponed or
tolled, as the case may be, until such conflict is no longer applicable. During
the Resale Period, if the realized net proceeds from the resale of the
Settlement Shares exceed the Forward Cash Settlement Amount, plus the Net Cash
Amount if applicable, GS shall refund such excess in cash to Counterparty by the
close of business on the third Exchange Business Day immediately following the
last day of the Resale Period. If the Forward Cash Settlement Amount, plus
the Net Cash Amount if applicable, exceeds the realized net proceeds from such
resale, Counterparty shall transfer to as by the open of the regular trading
session on the Exchange on the third Scheduled Trading Day immediately
following the last day of the Resale Period the amount of such excess (the
"Additional Amount") in cash or in the number of Shares ("Make-whole Shares") in
an amount that, based on the Net Share Settlement Price on the last day of the
Resale Period (as if such day was the "Net Share Valuation Date" for purposes of
computing such Net Share Settlement Price), has a dollar value equal to the
Additional Amount. The Resale Period shall continue to enable the sale of the
Make-whole Shares. If Counterparty elects to pay the Additional Amount in
Shares, the requirements and provisions set forth below shall apply. This
provision shall be applied successively until the Additional Amount is equal to
zero.

Net Share Settlement of a Transaction is subject to the following conditions:

Counterparty at its sole expense shall:

(i) as promptly as practicable (but in no event more than five (5) Exchange
Business Days immediately following the Settlement Method Election Date or, in
the case of an election of Net Share Settlement upon the occurrence of an
Extraordinary Event or an Early Termination Date, no more than three (3)
Exchange Business Day immediately following either the Cancellation Date or the
Early Termination Date, as the case may be) tile under the Securities Act and
use its best efforts to make effective, as promptly as practicable, a
registration statement or supplement or amend an outstanding registration
statement, in any such case, in form and substance reasonably satisfactory to as
(the "Registration Statement") covering the offering and sale by GS of not less
than 150% of the Shares necessary to fulfill the Net Share Settlement delivery
obligation by Counterparty (determining the number of such Shares to be
registered on the basis of the average of the Settlement Prices on the five (5)
Exchange Business Days prior to the date of such filing, amendment or
supplement, as the case may be), provided, however, that Counterparty shall not
be deemed to have failed to comply with its obligation to file the
Registration Statement until one (1) Exchange Business Day after GS&Co. has
indicated that the Registration Statement is reasonable in form and substance to
GS&Co. so long as Counterparty has delivered to GS&Co. a form of the
Registration Statement Counterparty believes to be acceptable for filing
prior to the expiration of the aforementioned five-day or three-day period, as
the case may be;

(ii) maintain the effectiveness of the Registration Statement until GS has sold
all shares to be delivered by Counterparty in satisfaction of its Net Share
Settlement obligations;

(iii)	have afforded GS and its counsel and other advisers a reasonable
opportunity to conduct a due diligence investigation of Counterparty customary
in scope for transactions in which GS acts as underwriter of equity securities,
and as shall have been reasonably satisfied (with the approval of its
Commitments Committee in accordance with its customary review process, which
such approval shall not be unreasonably withheld) with the results of such
investigation;

(iv) have negotiated and entered into an agreement with as providing for such
covenants, conditions, representations and warranties, underwriting discounts,
commissions, indemnities and contribution rights as are customary for GS equity
underwriting agreements, together with customary certificates and opinions of
counsel and letters of independent auditors of Counterparty to be delivered to
as covering the shares to be delivered by Counterparty in satisfaction of its
Net Share Settlement obligations;

(v) have delivered to GS such number of prospectuses relating thereto as
OS shall have reasonably requested and shall promptly update and provide GS with
replacement prospectuses as necessary to ensure the prospectus does not contain
any untrue statement of a material fact or any omission of a material fact
required to be stated therein or necessary to make the statements therein, in
the light of the circumstances in which they were made, not misleading;

(vi) reimburse GS for an underwriting counsel selected by GS (in its sole
discretion);

(vii) have taken all steps necessary for the shares sold by as to be listed or
quoted on the primary exchange or quotation system that the Shares are listed or
quoted on;

(viii) have paid all reasonable and actual out-of-pocket costs and expenses of
GS and all reasonable and actual fees and expenses of GS's outside counsel and
other independent experts in connection with the foregoing; and

(ix) take such action as is required to ensure that GS's sale of the Shares does
not violate, or result in a violation of, the federal or state securities laws.

In the event that the Registration Statement is not declared effective by the
Securities Exchange Commission (the "SEC") or any of the conditions specified in
(ii) through (ix) above are not satisfied on or prior to the Valuation Date (or,
in the case of an election of Net Share Settlement upon the occurrence of an
Extraordinary Event or an Early Termination Date, on or prior to the first
Exchange Business Day following either the Cancellation Date or the Early
Termination Date, as the case may be), then Counterparty may deliver
Unregistered Shares (as defined below) to OS in accordance with the following
conditions. If GS and Counterparty can agree on acceptable pricing (including
any applicable discounts to the Net Share Settlement Price at which GS can sell
the Unregistered Shares), procedures and documentation relating to the sale of
such Unregistered Shares (including, without limitation, applicable requirements
in (iii) through (ix) above and insofar as pertaining to private offerings),
then such Unregistered Shares shall be deemed to be the "Settlement Shares" or
"Make-whole Shares" for the purposes of the related Transaction and the
settlement procedure specified in this Annex C shall be followed.
Notwithstanding the delivery of the Unregistered Shares, Counterparty shall
endeavor in good faith to have a registration statement declared effective by
the SEC as soon as practical and shall use commercially reasonable
efforts to maintain the effectiveness of any such registration statement. In the
event that as has not sold sufficient Unregistered Shares to satisfy
Counterparty's obligations to as contained herein at the time that a
Registration Statement covering the offering and sale by GS of a number of
Shares equal in value to not less than 150% of the amount then owed to GS is
declared effective (based on the Net Share Settlement Price on the Exchange
Business Day (as if such Exchange Business Day were the "Net Share Valuation
Date" for purposes of computing such Net Share Settlement Price) that the
Registration Statement was declared effective), as shall return al1 unsold
Unregistered Shares to Counterparty and Counterparty shall deliver such number
of Shares covered by the effective Registration Statement equal to 100% of the
amount then owed to as based on such Net Share Settlement Price. Such
delivered shares shall be deemed to be the "Settlement Shares" for the purposes
of the related Transaction and the settlement procedure specified in this Master
Confirmation (including the obligation to deliver any Make-whole Shares, if
applicable) shall be followed. In all cases as shall be entitled to take any and
all required actions in the course of its sales of the Settlement Shares,
including without limitation making sales of the Unregistered Shares only to
"Qualified Institutional Buyers" (as such term is defined under the Securities
Act), to ensure that the sales of the Unregistered Shares and the Settlement
Shares covered by the Registration Statement are not integrated resulting
in a violation of the securities laws and Counterparty agrees to take all
actions requested by GS in furtherance thereof.

If GS and Counterparty cannot agree on acceptable pricing, procedures and
documentation relating to the sales of such Unregistered Shares then the number
of Unregistered Shares to be delivered to as pursuant to the provisions above
shall be based on the value attributed by as to each Unregistered Share in a
commercially reasonable manner and based on such value Counterparty shall
deliver a number of Shares equal in value to the Forward Cash Settlement Amount,
plus the Net Cash Amount, if applicable. For the purposes hereof "Unregistered
Shares" means Shares that have not been registered pursuant to an effective
registration statement under the Securities Act or any state securities laws
("Blue Sky Laws") and that cannot be sold, transferred, pledged or otherwise
disposed of without registration under the Securities Act or under applicable
Blue Sky Laws unless such sale, transfer, pledge or other disposition is made in
a transaction exempt from registration thereunder.

In the event that Counterparty delivers Shares pursuant to an election of Net
Share Settlement then Counterparty agrees to indemnify and hold harmless GS, its
affiliates and its assignees and their respective directors, officers,
employees, agents and controlling persons (as and each such person being an
"Indemnified Party") from and against any and all losses, claims, damages and
liabilities (or actions in respect thereof), joint or several, to which such
Indemnified Party may become subject, under the Securities Act or otherwise. (i)
relating to or arising out of any of the Transactions contemplated by this
Master Confirmation concerning Net Share Settlement or (ii) arising out of or
based upon any untrue statement or alleged untrue statement of a material fact
contained in any preliminary prospectus, prospectus. Registration Statement or
other written material relating to the Shares delivered to prospective
purchasers, including in each case any amendments or supplements thereto and
including but not limited to any documents deemed to be incorporated in any such
document by reference (the "Offering Materials"), or arising out of or based
upon any omission or alleged omission to state in the Offering Materials a
material fact necessary in order to make the statements therein, in the light of
the circumstances under which they were made, not misleading; provided, however,
that, in the case of this clause (i), Counterparty will not be liable to the
extent that any loss, claim, damage or liability arises out of or is based upon
any untrue statement or omission or alleged untrue statement or omission in the
Offering Materials made in reliance upon and in conformity with written
information furnished to Counterparty by as expressly for use in the Offering
Materials, as expressly identified in a letter to be delivered at the closing of
the delivery of Shares by Counterparty to GS.  For the avoidance of doubt, this
indemnification is not intended to influence the Company's selection of a
settlement procedure of this contract. The foregoing indemnity shall exc1ude
losses that as incurs solely by reason of the proceeds from the sale of a number
of Shares equal to the Capped Number (as defined below) being less than the
Forward Cash Settlement Amount plus any Net Cash Amount. Counterparty will not
be liable under the foregoing indemnification provision to the extent
that any loss, c1aim, damage, liability or expense is found in a nonappealable
judgment by a court of competent jurisdiction or arbitrator to have resulted
from GS's willful misconduct, gross negligence or bad faith in performing the
services that are subject of this Master Confirmation. If for any reason the
foregoing indemnification is unavailable to any Indemnified Party or
insufficient to hold harmless any Indemnified Party, then Counterparty shall
contribute, to the maximum extent permitted by law, to the amount paid or
payable by the Indemnified Party as a result of such loss, claim, damage or
liability. In addition, Counterparty will reimburse any Indemnified Party for
all expenses (including reasonable counsel fees and expenses) as they are
incurred (after notice to Counterparty) in connection with the investigation of,
preparation for or defense or settlement of any pending or threatened claim or
any action, suit or proceeding arising therefrom, whether or not such
Indemnified Party is a party thereto and whether or not such claim, action, suit
or proceeding is initiated or brought by or on behalf of Counterparty; provided
that such Indemnified Party is seeking a claim for indemnification in relation
to such expenses. In the event any Indemnified Party is found in a nonappealable
judgment by a court of competent jurisdiction or arbitrator to have acted in
gross negligence, willful misconduct or bad faith, such Indemnified Party
shall return any amounts paid by Counterparty to such Indemnified Party in
connection with such expenses.  Counterparty also agrees that no Indemnified
Party shall have any liability to Counterparty or any person asserting
claims on behalf of or in right of Counterparty in connection with or as a
result of Net Share Settlement except to the extent that any losses, claims,
damages, liabilities or expenses incurred by Counterparty result from the gross
negligence, willful misconduct or bad faith of the Indemnified Party. This
indemnity shall survive the completion of any Transaction contemplated by this
Master Confirmation and any assignment and delegation of a Transaction
made pursuant to this Master Confirmation or the Agreement shall inure to the
benefit of any permitted assignee of GS&Co.

In no event shall the number of Shares deliverable under these Net Share
Settlement procedures (equal to the number of Settlement Shares (including,
without duplication, any Unregistered Shares) and any Make-whole Shares), be
greater than an amount of Shares equal to (i) the Reserved Shares minus (ii) the
amount of any Shares actually delivered by Counterparty under any other
Transaction(s) under this Master Confirmation (the result of such calculation,
the "Capped Number"). Counterparty represents and warrants (which shall be
deemed to be repeated on each day that a Transaction is outstanding) that the
Capped Number is equal to or less than the number of Shares determined according
to the following formula:

                                     A-B

Where A = the number of authorized but unissued shares of Counterparty that are
not reserved for future issuance on the date of the determination of the Capped
Number; and

B = the maximum number of Shares that would be required to be delivered to third
parties if Counterparty elected Net Share Settlement for all other transactions
in the Shares (other than Transactions in the Shares under this Master
Confirmation) with all third parties that are then currently outstanding and
unexercised.<PAGE>

                                                                   EXHIBIT 10.30

      LEASE AGREEMENT made and entered into as of this 1st day of July, 2005, by
and between David A. Yarom, whose mailing address is 46 Westland Drive, Glen
Cove, NY 11542 (hereinafter referred to as "LESSOR"), and Nastech Pharmaceutical
Company Inc., a Delaware Corporation with a place of business at 45 Davids
Drive, Hauppauge, New York (hereinafter referred to as "LESSEE").

1.    LEASE.

      The LESSOR hereby leases to the LESSEE and the LESSEE hereby leases from
the LESSOR, subject to the conditions hereinafter set forth, the building, known
as 45 Davids Drive, Hauppauge, NY, together with the right of LESSEE, its
employees and invitees to use entrances, parking areas, walkways, public and
common areas and any other appurtenances to the Leased Property.

2.    LESSOR'S WARRANTIES.

      2.1   The LESSOR represents and warrants (which representations and
warranties shall survive the execution of this Lease), that he is the sole Owner
of the Leased Property; that he has the right to lease the herein premises to
the Lessee.

      2.2   Neither the LESSOR nor its agents have made or make any
representations or warranty with respect to the Leased Property except as
expressly set forth herein.

      2.3   LESSOR represents premises are zoned light industrial.

      2.4   The LESSEE acknowledges that it has examined the Leased Property and
that the Leased Property is accepted, as is, in its present condition and state
of repair.

3.    TERM

      3.1   The Term of this lease shall be for five (5) years to commence on
July 1, 2005 and to end on June 30, 2010, unless sooner terminated in accordance
with the provisions of this lease, or otherwise. In the event that the
commencement date of this Lease or any extension or renewal thereof falls on
other than the first day of the month, then the LESSEE shall pay a pro-rated
rent for said partial month, and the balance of the term of the lease shall be
adjusted to run from the first day of the following month.

<PAGE>

      Should the LESSEE hold over or remain in possession of the Leased Property
after the expiration of this lease, or any renewal or extension thereof, without
the LESSOR's consent, such holdover shall not be deemed or construed to be a
renewal or an extension of this lease, but shall only operate to create a "month
to month" tenancy which may be terminated by the LESSOR at the end of any
calendar month upon 30 days prior written notice to the LESSEE. During any such
month of the "month to month" tenancy, fixed, minimum base rent shall be payable
at one and one-half times the rate as that in effect during the last month of
the preceding term, and the provisions of this lease shall be applicable to such
"month to month" or holdover tenancy.

4.    RENT

      4.1   The LESSEE agrees to pay to LESSOR's office at the address first
hereinabove set forth, or at such other place as LESSOR may designate, in
writing, the amount of the fixed minimum base rent, "fixed rent", in advance on
the first day of each calendar month during the term of this Lease and any
extension or renewal thereof or any month to month tenancy created hereunder,
according to the annexed "Rent Schedule." LESSEE agrees to make such rental
payments in full without any right to prior demand or set-off or deduction
whatsoever, except as expressly provided herein.

      Any extension of time for payment of any installment of rent granted by
the LESSOR shall not constitute a waiver of the LESSOR's right to have all other
payments of rent made in a timely manner as herein specified. Time is of the
essence with respect to each monthly installment of rent due hereunder, beyond
any applicable grace periods hereunder.

      In the event LESSEE fails to pay the rent on or before the 10th day of the
month in which same is due ("Grace Period"), the LESSEE shall pay the LESSOR as
a "late charge", an additional sum equal to six (6%) percent of the rent
remaining unpaid.

      4.2   It is intended that the " fixed rent" provided for in paragraph 4.1
hereof, shall be net of any cost, tax, imposition, expense, charge, abatement or
setoff or other deduction whatsoever, with respect to the leasing operation,
management, maintenance, repair, rebuilding, use or occupation of the Leased
Property with respect to any interest of LESSOR therein except only as otherwise
expressly provided in paragraph 7.6 of this lease. The LESSEE agrees to pay all
such costs, impositions, expenses, charges with respect to the Leased Property
as "Additional Rent" and indemnify the LESSOR against such costs, expenses and
charges.

5.    SECURITY DEPOSIT

      The LESSEE shall deposit with the LESSOR, upon execution of this Lease,
the sum of $18,000.00 (Eighteen Thousand Dollars) as security for the full and
faithful performance by the LESSEE of all of the terms, covenants and conditions
of this Lease upon the LESSEE's part to be performed. Said security deposit
shall be returned to the LESSEE, with interest, within thirty (30) days after
the time fixed as the expiration of the lease or any extension or renewal
thereof herein, or any other permitted earlier termination provided the LESSEE
has fully and faithfully carried out all of the said terms, covenants and
conditions on LESSEE's part to be performed. In the event of a bonafide sale,
subject to this lease, the LESSOR shall transfer the security to the vendee for
the benefit of the LESSEE and the LESSOR shall be considered released by the
LESSEE from all liability for the return of such security; and the LESSEE agrees
to look to the new LESSOR solely for the return of the said security. The
security deposited under this lease shall not be mortgaged, assigned or
encumbered by the LESSEE without the prior, written consent of the LESSOR, nor
shall it be used as or towards the final rental payments due hereunder.

6.    TAX ABATEMENTS

<PAGE>

      The parties agree that the LESSEE shall receive the benefit of any
decrease in taxes attributable to the premises due by reason of any business tax
exemptions, if any, or the equivalent thereto, with respect to the Leased
Property, applicable to the period beginning on the commencement date of the
lease, but only for the period LESSEE is a tenant hereunder and only if LESSEE
is not in default hereunder, beyond applicable periods of notice or grace.

7.    ADDITIONAL RENT

      7.1   The LESSEE shall pay as Additional Rent, before any fine, penalty,
interest or cost may be added thereto for the non-payment thereof, any sewer
rents, water rates and water charges and other governmental levies and charges,
general and special, ordinary and extraordinary, unforeseen as well as foreseen,
which are assessed or imposed upon and attributable to the Leased Property or
any part thereof or which become payable during the term of this lease. If any
such payments are payable in more than one installment to the authority (i.e.,
real estate taxes), then LESSEE shall be entitled to make such payments in
installments, as billed for same.

      7.2   The LESSEE shall also pay as additional rent, all charges for
real-estate taxes, gas, water, sewer, electricity, , heat, garbage removal, and
telephone and other communications and utilities services used, rendered or
supplied upon or in connection with the Leased Property and the cost of repair,
maintenance, replacement and reading of any meters measuring LESSEE's
consumption thereof, and LESSEE shall indemnify the LESSOR against any liability
or damages on such account. Other than as may be required by law, the LESSOR
shall not be required to furnish to the LESSEE any facilities or services of any
kind such as, but not limited to, water, steam heat, gas, hot water, garbage
removal, electricity, light, power or any and all forms of communications, all
costs for which remain LESSEE's responsibility.

      7.3 a  All of the items in subsection 7.1 and 7.2 hereof shall be referred
to as "Additional Rent" and shall be the responsibility of the LESSEE. If any of
the impositions required to be paid pursuant to paragraphs 7.1 and 7.2 hereof
are billed to LESSEE by the LESSOR directly, then such Additional Rent shall be
paid to LESSOR within fifteen (15) days from the date of an itemized bill from
LESSOR. Payments of Additional Rent made after said due date shall carry
interest at the Chemical Bank or any successor bank thereto prime rate
established at the time the monies are due, plus 2%.

      7.3 b. Anything herein to the contrary not withstanding, LESSOR shall
supply LESSEE with all reasonable documentation to support its bill for
additional rent if requested by the LESSEE.

      7.4   LESSOR represents that the premises are fully assessed for real
estate taxes without exemption and have, to date, received no notice of any
change in assessed valuation. All taxes or payments assessed prior to but
payable in whole or in installments after the effective date of the lease and
all taxes assessed during the term but payable in whole or in installments after
the lease term shall be adjusted and pro-rated so that the LESSOR shall pay his
pro-rata share of such taxes for the period prior to and following the lease
term, and the LESSEE shall pay its pro-rate share of such taxes for the lease
term.

      7.5   LESSEE, at its own cost and expense, may faithfully contest any
impositions mentioned in paragraphs 7.1 and 7.2 hereof in any manner permitted
by law, in LESSEE's name, and whenever necessary, in LESSOR's name. LESSOR will
reasonably cooperate with LESSEE in such contest. Such contest may include
appeals from any judgment, decrees or orders until a final determination is made
by a court or governmental department or authority having final jurisdiction in
the matter. However, notwithstanding such contest, LESSEE shall pay the
contested imposition in the manner and on the dates due unless the imposing
authority permits the withholding of payment pending outcome of such appeal or
contest, without

<PAGE>

risk or jeopardy to LESSOR's property, and further provided that the LESSEE
shall set up adequate reserves with respect to such payments and the LESSOR
shall give his consent to such withholding, which consent shall not be
unreasonably withheld. Any refund with respect to impositions paid by LESSEE
shall be the property of the LESSEE. LESSEE shall arrange for and pay all costs
associated with the contest any impositions mentioned in paragraphs 7.1 and 7.2.

      7.6   LESSEE shall not be obligated or required hereunder to pay any
estate, excise, inheritance, succession, capital levy, mortgage or transfer tax
of LESSOR, or any income, profit, franchise or revenue tax upon the income or
receipts of LESSOR, or any other tax, assessment charge or levy upon the rent
reserved under this lease, or any tax or other imposition, charge or levy (i)
not commonly deemed to be either a real estate tax or ad valorem or similar
personal property, ownership or use tax, and (ii) not arising solely from the
ownership, occupation or operation of the demised premises, although the same
may be or become a lien upon the real property or improvements thereon, nor
shall LESSEE be obligated or required hereunder to pay interest, amortization or
principal on any mortgage given by LESSOR covering or affecting the fee of the
demised premises, or expenses of leasing or sale, nor LESSOR's depreciation
expense.

      7.7   If during the term of this lease there shall be levied or assessed
any imposition on rents or against the fixed annual rent or against LESSOR, or
the Leased Property not in effect on the commencement date of the Lease Term, as
a substitute in whole or in part of real estate taxes on land or buildings such
imposition shall be included within those payable by LESSEE pursuant to
paragraph 7.1 above.

      7.8   In the event the LESSEE fails to pay the Additional Rent or any part
thereof when due, the LESSOR shall have all of the rights and remedies with
respect thereto as the LESSOR has for the non-payment of the rent called for
pursuant to paragraph 4.1 hereof, except for the penalty described in section
7.3.

8.    USE OF LEASED PROPERTY

      The LESSEE may use and occupy the Leased Property for fill and finish,
design, manufacture and sale of its products, warehousing of inventory, light
assembly, electronic component testing and general business and uses incidental
to the aforementioned purposes, except that the LESSEE shall not use or occupy
and/or permit the Leased Property or any part thereof to be used or occupied,
for any unlawful business, use or purpose, nor for any business, use or purpose
deemed disreputable , nor for any purpose other than as permitted above, which,
in the reasonable judgment of the LESSOR, would reduce the value of the said
premises, nor for any purpose or in any manner which is in violation of any
present or future governmental laws or regulations. The LESSEE shall promptly,
after discovery of any such unlawful, disreputable use take all necessary steps,
legal and equitable, to compel the discontinuance of such use and to oust and
remove any sublessees, occupants or other persons guilty of such unlawful or
disreputable use. The LESSEE shall indemnify the LESSOR against all costs,
expenses, liability losses, damages, injunctions, suits, fines, penalties,
claims and demands including reasonable counsel fees arising out of any
violation or default in these covenants. The LESSEE shall also not use or occupy
or permit the Leased Property to be used or occupied or permit anything to be
done in or on he Leased Property in a manner which will in any way violate any
certificate of occupancy or building or zoning law affecting the Leased Property
or which would make void or voidable any insurance then in force with respect
thereto or which will cause or be likely to cause structural damage to the
building or any part thereof or which will constitute a public or private
nuisance. In the event that the LESSEE's hazardous or particular use of use of
the premises increases the LESSOR's insurance premiums for the premises, the
LESSEE shall pay the increase attributable thereto as additional rent.

9.    MAINTENANCE AND REPAIR

<PAGE>

      The LESSEE shall not cause or permit any waste, damage or injury to the
Leased Property and shall, at the expiration of this lease, return the Leased
Property to the LESSOR in as good and safe order and condition as when received
hereunder, reasonable wear and tear excepted. The LESSEE, at its sole expense,
shall keep such Leased Property as now or hereafter constituted with all
improvements made thereto and the HVAC, adjoining walks, curbs, walls, roof,
parking areas, driveways and access roads used by LESSEE in good and safe
condition, reasonable wear and tear excepted and shall make all repairs,
replacements or renewals whether ordinary or extraordinary, seen or unforeseen,
including all interior and exterior structural repairs. All repairs, fixtures
and equipment shall be at least equal in quality and material and workmanship to
that originally existing in the Leased Property. The LESSOR shall in no event be
required to make any repair, alteration, or improvement to the Leased Property
except repair necessitated due to LESSOR's misconduct. LESSEE shall be
responsible for costs attribable to and arrange for the maintenance of the
parking areas, loading docks, walkways, etc., and such maintenance shall
include, but not be limited to, snow removal, landscaping, lawn care and
resealing. LESSEE shall be responsible for costs attributable to and arrange for
the maintenance of the parking areas, loading docks, walkways, etc., and such
maintenance shall include, but not be limited to, snow removal, landscaping and
lawn care, resealing and repaving, and all other maintenance. This provision
shall not be deemed to require LESSEE to repair, restore or rebuild all or any
part of the Leased Property in the event of casualty, destruction or
condemnation as set forth in paragraph 12.

10.   IMPROVEMENTS

      No alteration, addition or improvement to the Leased Property shall be
made by the LESSEE without the prior written consent of the LESSOR, which shall
not be unreasonably withheld, and without LESSEE first obtaining any and all
required permits therefor. At the time that the LESSOR provides written consent
for proposed alterations, additions or improvements, LESSOR shall also indicate
whether the LESSEE shall be required to remove said alterations, additions or
improvements and restore those portions of the premises at lease end or earlier
termination thereof. This requirement that LESSEE first obtain LESSOR's written
consent for alterations, additions or improvements shall not apply to LESSEE's
installation of machinery, equipment and fixtures used in the conduct of
LESSEE's business (hereinafter referred to as LESSEE's "Trade Fixtures") except
for equipment or machinery which may affect the structural integrity of the
building. Any alteration, addition or improvement made by the LESSEE, after such
consent shall have been given, and any fixtures installed as a part thereof
(except LESSEE's Trade Fixtures, which shall be removed by LESSEE upon
termination of this Lease), shall be deemed to be part of the premises and shall
become the property of the LESSOR upon the termination or expiration of this
Lease any renewal or extension thereof. No signs may be installed or affixed to
the exterior of the Premises without LESSOR's prior written approval, which
approval shall not be unreasonably withheld.

      Within 30 days of presentation of paid bills, LESSOR shall re-pay LESSEE
for 50% of the cost incurred by LESSEE, up to a total of $24,000., of the
following improvements to the premises:

1.    Upgrade lavatories/restrooms.

2.    Upgrade main building entrance including handicapped access.

3.    Upgrade the air conditioning system to improve heating/cooling.

      In no event shall LESSOR be liable or obligated to LESSEE for more than
$24,000. All construction/alterations at the premises shall be performed in
conformity with all applicable codes and laws. LESSOR reserves the right to
inspect said repairs/alterations at reasonable times to confirm completion of
work in bills presented under this article.

<PAGE>

11.   COMPLIANCE WITH LAWS

      The LESSEE shall through the term of this lease, at its sole expense,
promptly comply with all laws and regulations of all federal, state, municipal
governments and appropriate departments, agencies, commissions, boards and
offices thereof, and the orders and regulations of the National Board of Fire
Underwriters or any other party, now or hereafter exercising similar functions
which may be applicable to the business, use, operation or maintenance of the
Leased Property by LESSEE. The LESSEE shall comply with the requirements of all
policies of public liability, fire and all other types of insurance at any time
in force with respect to the Leased Property. The LESSEE, at its sole expense,
shall obtain all licenses and/or permits which may be required for the conduct
of its business within the terms of this lease and for making of repairs,
alterations, improvements or additions necessary for the particular business and
in conformity with any health or building department requirements, and the
LESSOR, where required, will join with the LESSEE in applying for all such
permits or licenses. LESSEE shall promptly provide LESSOR with copies of all
such permits and/or certificates of occupancy covering all such repairs,
alterations, improvements or additions.

12.   INSURANCE AND RISK OF LOSS

      12.1  Except as set forth herein, no destruction or damage to any building
or improvement on the Leased Property by fire, windstorm, or any other casualty,
or a taking by condemnation or other governmental authority of less than 25% of
the Leased Property, shall entitle LESSEE to surrender possession of the Leased
Property, to terminate the Lease or to violate any of its provisions. In the
event of a governmental taking of up to 25% of the building located upon the
Leased Property, or up to 50% of the parking areas located on the Leased
Property, or in the event of any damage to or destruction of the Leased Property
by fire or other casualty, the LESSOR shall promptly restore and/or relocate the
Leased Property as nearly as possible to its condition prior to such damage or
destruction and shall use the net proceeds of any insurance or condemnation for
that purpose only. In such case of government taking, and provided LESSEE's
business cannot operate from said premises during the reconstruction or
restoration of same, LESSOR shall pro-rate the rent and deduct therefrom the
proportionate amount not able to be used up to the 25%. In the event of a
government taking or condemnation of the building in excess of 25% thereof, or
of the parking areas by more than 50%, this lease shall be terminated at the
option of the LESSEE upon giving LESSOR thirty (30) days written notice from the
date of such condemnation, and the LESSEE shall, upon vacating the Leased
Premises, be released from further liability hereunder effective upon the date
of taking. All insurance or condemnation proceeds resulting from a casualty
claim shall be held by the LESSOR or the mortgagee(s) of the premises, and
applied in payment of restoration and/or relocation of the Premises as such
restoration relocation progresses. Such restoration, relocation, repair or
replacement, rebuilding or alteration shall be commenced by LESSOR as soon as
practicable, after receipt of insurance proceeds, unless such destruction or
damage is of such magnitude that LESSOR or its mortgagee, in their sole
discretion shall decide not to rebuild or restore, in which event LESSOR shall
give LESSEE written notice of such intention, with ninety (90) days from the
date of fire or casualty, and thereupon this Lease shall terminate with LESSEE
being under no further obligation with respect to future payments under the term
of the Lease. Unless LESSOR shall terminate as provided for herein, LESSOR shall
make the repairs and restorations under the conditions hereof, subject to delays
due to adjustment of insurance claims, labor troubles and causes beyond LESSOR's
control, but in any event, such Premises shall be substantially restored within
twelve (12) months from the date of such casualty or loss. In the event the
Premises are not substantially restored within said twelve (12) month period,
then, within ten (10) days after the expiration of said period of time, LESSEE
shall have the right to terminate this Lease, by written notice to the LESSOR,
and LESSEE shall thereafter be under no further obligation hereunder with
respect to Future Rents or obligations. LESSEE shall also have the right to
terminate if, in its discretion, so much the premises is destroyed that it
cannot operate its business or if the damage occurs during the last year of the
lease term. After any such casualty, LESSEE shall cooperate with LESSOR's
restoration by removing from the premises as promptly as possible, all of

<PAGE>

LESSEE's moveable equipment, furniture and other property. Nothing contained
herein shall relieve LESSEE from liability which may exist as a result of damage
from fire or other casualty caused by its negligence, acts or omissions or those
of its agents or invitees. Notwithstanding the foregoing, each party shall look
first to any insurance in its favor before making any claim against the other
party for recovery for loss or damage resulting from fire or other casualty to
the extent that such insurance is in force and collectible. LESSEE acknowledges
that LESSOR will not carry insurance on LESSEE's inventory, furniture and/or
furnishings or any equipment, improvements or fixtures removeable by LESSEE and
agrees that LESSOR will not be obligated to repair any damage thereto or replace
the same. LESSEE hereby waives the provisions of Section 227 of the Real
Property Law and agrees that the provisions of this article shall govern and
control in lieu thereof.

      12.2  During the term of this lease, or any renewal thereof, LESSEE shall
at its own cost and expense provide and keep in force the following insurance:

            12.2.1 Comprehensive public liability insurance for the mutual
benefit of LESSOR, and LESSEE against claims for bodily injury, death or
property damage occurring in or about the Leased Property (including, without
limitation, bodily injury, death or property damage resulting directly or
indirectly from or in connection with any change, alteration, improvement or
repair thereof), with limits of not less than $2,000,000.00 for bodily injury or
death and property damage, which insurance may be carried under a so-called
"blanket" or "umbrella" policy;

            12.2.2 Such other insurance, in such amounts that may from time to
time be reasonably requested by LESSOR, LESSOR's mortgagee or any governmental
authority, against other insurable hazards which at the time are reasonably
available and commonly insured against in the case of premises or buildings
similarly situated, with due regard to the height and the type of the premises,
its constructions, use and occupancy including, but not limited to, boiler
insurance and machinery insurance.

            12.2.3 Insurance covering the Premises for the mutual benefit of
LESSOR, LESSEE, and any mortgagees hereunder, against loss or damage by fire and
lightning and such other risks as are customarily including in extended coverage
endorsements attached to fire insurance policies covering property similar to
such premises in an amount equal to $1,000,000 (excluding foundations and
excavation costs and LESSEE's contents).

      12.3  All insurance to be provided and kept in force by LESSEE under the
provisions hereof shall include as additional insureds, the LESSOR, LESSEE and
any named mortgagee hereunder as their respective interests may appear.

      12.4  All policies required herein to be obtained by LESSEE and
certificates thereof shall be delivered to LESSOR at or before the commencement
of the term hereof and shall be taken with responsible companies satisfactory to
LESSOR and authorized to do business in the State of New York. All policies
shall be for a period of not less than one (1) year and shall contain a
provision whereby the same cannot be cancelled unless LESSOR is given at least
thirty (30) days written notice of such cancellation. Such policies shall also
contain waivers of subrogation in favor of the LESSOR. LESSEE shall procure and
pay for renewals of such insurance from time to time and LESSEE shall promptly
deliver to LESSOR certificates thereof at least fifteen(15) days before the
expiration thereof, providing for fire and extended coverage and certificates
for liability coverage prior to the expiration thereof.

      12.5  LESSEE hereby released LESSOR, its agents and assignees from any and
all liability or responsibility to it or anyone claiming through or under it by
way of subrogation or otherwise, for any loss or damage to property or business,
including loss or damage to LESSEE's goods or property, or to the Leased
Property from fire, lightning, water, or any of the extended coverage
casualties, whether or not insured unless caused by the willfull misconduct of
LESSOR.

<PAGE>

13.   ASSIGNMENT/SUBLETTING

      13.1  The LESSEE may not sublet or assign the Leased Property for any
portion of the remainder of the term of this lease, or any extension or renewal
thereof, without the prior written consent of the LESSOR which consent LESSOR
agrees shall not be unreasonably withheld. However, LESSOR may set such
conditions as he reasonably deems appropriate to such consent, including but not
limited to, the right of the LESSOR and any mortgagees hereunder to approve the
form of assignment/sublease, the financial condition of the assignee/sublessee,
the type of business or occupation of the sublessee or assignee which shall not
be, disreputable, illegal and that the LESSEE shall remain primarily liable for
the payment of the rent and Additional Rent herein and for the performance of
all of the other terms of this lease required to be performed by the LESSEE.
LESSEE shall give LESSOR written notice of its desire to so sublease or assign,
which notice shall be accompanied by a copy of the proposed Sublease or
assignment. The consent by LESSOR to any assignment or subletting shall not be
construed in any way to relieve LESSEE from obtaining the express consent in
writing of LESSOR to any further assignment or subletting. Consent shall not be
required for an assignment or subletting by the LESSEE to a corporation which
owns, is owned by, or is under common control of LESSEE, whether such ownership
or control is immediate or through ownership or control of other Corporations,
or to a corporate successor of LESSEE, whether by merger, acquisition or stock
purchase. For purposes of the foregoing sentence, in order to establish
ownership or common control, each order to establish ownership or common
control, each Corporation in the chain of ownership or control must own at least
50% of the voting securities of its immediate subsidiary in such chain of
ownership or control. Notwithstanding such consent, LESSEE shall not be relieved
from liability under the lease, and further, such subletting or assignment shall
comply with the remaining prerequisites listed above.

      13.2  In the event that the LESSOR consents to any assignment or
subletting of the Leased Premises by the LESSEE, the LESSOR may impose a
condition upon said consent that LESSEE thereafter to pay to LESSOR a sum equal
to 50% (i) subtenant or assignee which is in excess of the fixed annual rent and
Additional Rent and other amounts then being paid by LESSEE to LESSOR pursuant
to the terms of this Lease, and (ii) any other profit or gain realized by LESSEE
directly as a result of any such assignment or subletting (in computing any
profit to be paid LESSOR hereunder there shall be deducted all reasonable
expenses incurred by LESSEE in connection with the assignment or particular
subletting, including any reasonable attorneys fees or customary brokerage
commissions paid to an unaffiliated broker or agent). Nothing contained in this
paragraph shall require LESSEE to pay to LESSOR any profit or gain realized by
LESSEE from any such assignment or subletting until LESSEE has actually received
payment thereof by such assignee or subtenant.

      13.3  Notwithstanding any of the above, following LESSEE's written notice
of a proposed assignment or Sub-Lease as provided in Section 13.1, of more than
75% of the Leased Property, LESSOR shall have the sole option, in its
discretion, in lieu of granting or accepting any assignment or sublease, to
terminate the Lease hereunder. This right of LESSOR to terminate pursuant to
this section shall not apply to an Sub-Lease or assignment not requiring
LESSOR's prior consent.

14    COVENANT OF QUIET ENJOYMENT

      The LESSEE, upon paying the rent and all Additional Rent and other charges
herein provided for and performing all of the other terms of this lease on its
part to be performed shall quietly have and enjoy the Leased Property, during
the term of this lease or any renewal thereof without hinderance or molestation.

15.   RIGHT OF ENTRY

<PAGE>

      The LESSOR or its agents shall have the right to enter the Leased Property
at all reasonable times upon reasonable notice (except in emergencies) in order
to examine it, and to show it to mortgagees, or prospective lessees (within the
last six (6) months of the term) or to make such repairs, alterations,
improvements or additions as necessary to keep the Premises in proper order and
repair. The LESSOR shall be allowed to take all material into or upon the Leased
Property that may be required therefor without the same constituting an eviction
of the LESSEE in whole or in part. Neither the rent nor the Additional Rent
shall abate while repairs, alterations, improvements or additions are being
made, whether by reason of loss or interruption of the business of the LESSEE.
or otherwise. LESSOR shall not unreasonably delay in making repairs/alterations
referred to in this paragraph. During the six months prior to the expiration of
this Lease, LESSOR may list the Leased Property with a broker or real estate
agent for the purpose of reletting the Leased Property and may post "To Let" or
other appropriate signs on the property. If required by law, rule or regulation,
the LESSOR shall have the right at any time without effecting an actual or
constructive eviction and without incurring any liability to the LESSEE therefor
to change the arrangement or location of entrances or passageways, doors and
doorways, corridors, elevators, driveways, stairs, toilets or other public parts
of the building (and if LESSOR undertakes same, shall complete same with
reasonable diligence) and to change the name, number or designation by which the
building is commonly known. If at any time during the term of this lease the
Leased Property or any part thereof shall be abandoned for more than 10
consecutive days by the LESSEE, the LESSOR may at its option enter into the
Leased Property by force or otherwise, without being liable to the LESSEE for
damages for any payment of any kind whatsoever (unless damage to the Premises
caused by the gross negligence of the LESSOR) and may in its uncontrolled
discretion, as an agent of the LESSEE, relet the Leased Property or any part
thereof for the whole or any part of the then unexpired term and for the
purposes of such reletting, LESSOR may make necessary alterations and
modifications of the Leased Property and may receive and collect all rent
payable by virtue of such reletting. If the LESSOR shall, because of non-payment
of rent, the Additional Rent or other breach of condition or covenants or
agreement on the part of the LESSEE, re-enter and repossess the Leased Property
pursuant to the conditions and limitations contained therein by summary
proceeding or otherwise, the LESSOR may, at its option, hold the LESSEE liable
for the difference between the rent and other charges that would have been
payable hereunder during the remainder of the leased term, as if this lease had
contained in full force and the net rent for such period realized by the LESSOR
by means of reletting to any party or parties on such terms and conditions as
any in the uncontrolled discretion of the LESSOR be provided and the LESSEE
shall pay monthly in advance at such periods at the rent hereunder would have
fallen due, if this lease continued, the difference between the original amount
of each monthly payment as herein provided plus such sums, if any, due from the
LESSEE as Additional Rent and the net proceeds of reletting after deducting
expenses of every nature and description incurred by the LESSOR, including
commissions and the reasonable cost of all alterations and modifications to the
Leased Property made in reletting same.

16    SURRENDER OF LEASED PROPERTY

      The LESSEE shall on the last day of the term, or upon the sooner
termination of the lease, any extension or renewal thereof, peacefully and
quietly surrender the Leased Property to the LESSOR, broom clean, in as good
condition or repair as at the commencemyn of the term, with normal wear and tear
thereof excepted. The LESSEE shall remove all improvements and replacements
which are LESSEE's property and, if such removal damages the Leased Property,
LESSEE shall repair and restore the Leased Property in conformity with this
paragraph.

17    SELF-HELP

      LESSEE convenants and agrees that if it shall at any time fail to make any
payments or perform any act which the LESSEE is obligated to make or perform
under this lease within fifteen (15) days after LESSEE's time to make any such
payment or perform any act has expired including applicable periods of notice or
grace then the LESSOR may, but shall not be

<PAGE>

obligated so to do, and without waiving, or releasing the LESSEE from any
obligations of the LESSEE in this lease contained, make any payment or perform
any act which the LESSEE is obligated to perform under this lease, in such
manner and to such extent as shall be necessary, and in exercising any such
rights, reasonably pay necessary and incidental costs and expenses, employ
counsel and incur and pay reasonable attorneys' fees. Notwithstanding the
foregoing, LESSOR may make any such payment or perform any such act before
LESSEE's time to do so as provided herein has expired if the same is necessary
to protect the structural integrity of the building or as required by law,
governmental authority, LESSOR's mortgagee, insurance company or rating company,
and charge to LESSEE the incidental costs and expenses in connection with the
performance of any such act by LESSOR, shall be deemed Additional Rent hereunder
and, except as otherwise in this lease expressly provided, shall be payable to
LESSOR on demand or at the option of the LESSOR may be added to any rent then
due or thereafter becoming due under this lease, and LESSEE covenants to pay any
such sum or sums with interest as aforesaid and LESSOR shall have (in addition
to any other right or remedies of LESSOR), the same rights and remedies in the
event of the non-payment thereof by LESSEE as in the case of default by LESSEE
in the payment of rent.

18    DEFAULT

      18.1  The occurrence of any of the following shall constitute an event of
default:

            (a)   Delinquency in the payment of any rent or Additional Rent
payable under this lease after (5) days notice from LESSOR beyond any applicable
grace period.

            (b)   Delinquency or failure by the LESSEE in the performance of or
compliance with any of the conditions contained in this lease other than those
referred to in the foregoing subparagraph (a), for a period of fifteen (15) days
after written notice by LESSOR of such occurrence, unless said delinquency or
failure is not capable of being cured wtihin said period of time, but LESSEE
commences curing within fifteen (15) days and diligently works towards
completing such cure which, in any event, must be completed withnt sixty (60)
days.

            (c)   Filing by the LESSEE in any court pursuant to any statute,
either of the United States or any state, of a petition in bankruptcy or
insolvency, or for reorganization, or for the appointment of a receiver or
trustee of all or a portion of the LESSEE's property, or an assignment by the
LESSEE for the benefit of creditors.

            (d)   Filing against the LESSEE in any court pursuant to any
statute, either of the United States or of any state, of a petition in
bankruptcy or insolvency, or for reorganization, or for appointment of a
receiver or trustee of all or a portion of the LESSEE's property, if within
sixty (60) days after the commencement of any such proceedings against the
LESSEE such petition shall not have been dismissed or discharged.

            (e)   If LESSEE shall assign, record, mortgage or encumber this
lease or sublet the whole or any part of the Leased Property, otherwise than as
expressly permitted hereunder.

            (f)   If LESSEE shall abandon the Leased Property for more than 10
consecutive days or fail to keep the premises occupied to the extent necessary
to maintain fire insurance coverage. The LESSEE shall not be deemed to have
abandoned the Premises if LESSEE continues to make payments of rent when due and
Additional Rent required under the Lease.

            (g)   If any execution, attachment or levy shall be issued against
LESSEE or a substantial portion of LESSEE's property which is not dismissed,
discharged, stayed or bonded within thirty (30) days after issuance, or where
the premises shall be, or attempted to

<PAGE>

be, taken or occupied by someone other than LESSEE (except where permitted by
assignment or sublease).

            (h)   If a petition or a proceeding is filed or commenced by or
against LESSEE for its dissolution of liquidation, or if its property is taken
by any governmental authority in connection with a dissolution or liquidation,
and if filed or commenced against LESSEE, the same is not dismissed within
thirty (30) days.

            (i)   If LESSEE shall dissolve or if it shall sell or liquidate
substantially all of its assets Except as permitted pursuant section 13.1
herein.

      18.2  Upon the occurrence of an event of default, the LESSOR at any time
thereafter may give written notice to the LESSEE specifying such event of
default and stating that this lease shall expire on the date specified in such
notice, which shall be at least ten (10) days after the giving of such notice,
and upon the date specified in such notice this lease and all rights of the
LESSEE hereunder shall terminate. LESSEE hereby waives any and all rights of
redemption under the laws of the State of New York.

      18.3  Upon the termination of this lease pursuant to paragraph 18.2 of
this article the LESSEE shall peacefully surrender the Leased Property to the
LESSOR, and the LESSOR, upon or at any time after any such termination, may
without further notice re-enter the Leased Property and repossess it as
permitted by summary proceedings, ejectment or otherwise, and may dispossess the
LESSEE and remove the LESSEE and all other persons and property from the Leased
Property and may have, hold and enjoy the Leased Property and the right to
receive all rental income therefrom.

      18.4  At any time after any such termination, the LESSOR may relet the
Leased Property or any part thereof, in the name of the LESSOR or otherwise, for
such term (which may be greater or less than the period which would otherwise
have constituted the balance of the term of this lease, or the renewal term, if
any) and on such conditions (which may include concessions or free rent) as the
LESSOR, in its discretion, may determine, and may collect and receive the rent
therefor. The LESSOR shall in no way be responsible or liable for any failure to
relet the Leased Property or any part thereof, or for any failure to collect any
rent due upon such reletting.

      18.5  No such termination of this lease shall relieve the LESSEE of its
liability and obligations under this lease, and such liability and obligations
shall survive any such termination. In the event of any such termination,
whether or not the Leased Property or any part thereof shall have been relet,
the LESSEE shall pay to the LESSOR the rent and Additional Rent required to be
paid by the LESSEE up to the time of such termination, and thereafter the
LESSEE, until the end of what would have been the term of this lease in the
absence of such termination, shall be liable to the LESSOR for, and shall pay to
the LESSOR, as and for liquidated and agreed current damages for the LESSEE's
default:

            (a)   the equivalent of the full amount of the rent and Additional
Rent which would be payable under this lease by the LESSEE if this lease were
still in effect, less:

            (b)   the net proceeds of any reletting effected pursuant to the
provisions of paragraph 18.4 of this article, after deducting all the LESSOR's
reasonable expenses in connection with such reletting, including, without
limitation, all repossession costs, brokerage commissions, legal expenses,
reasonable attorneys' fees, reasonable alteration costs and expenses of
preparation for such reletting.

      18.6  The LESSEE shall pay such current damages, herein called deficiency,
to the LESSOR monthly on the days on which the rent and Additional Rent would
have been payable under this lease if this lease were still in effect, and the
LESSOR shall be entitled to

<PAGE>

recover from the LESSEE each monthly deficiency as such deficiency shall arise,
or obtain a judgment (which is hereby consented to) for the full amount due or
to become due as per paragraph (a) above, giving credit, from time to time in
the nature or a partial satisfaction piece, for the items in sub-paragraph (b)
above, which, if previously collected from LESSEE, shall be remitted and
returned to LESSEE, as collected.

      18.7  In case suit shall be brought for recovery of possession of the
Leased Premises, for the recovery of rent or any other amount due under the
provisions of this Lease, or because of any breach of any other covenant herein
contained on the part of the LESSEE to be kept or performed, LESSEE shall pay to
LESSOR all expenses incurred therefor, including reasonable attorneys fees, All
said monies, including legal fees, shall be deemed to be Additional Rent herein.

19    CUMULATIVE REMEDIES, WAIVER ORAL CHANGE

      19.1  Every term, condition, agreement or provision contained in this
lease shall be deemed to be also a covenant.

      19.2  The specified remedies to which the LESSOR may resort under the
terms of this lease are cumulative and are not intended to be exclusive of any
other remedies or means of redress to which LESSOR may be lawfully entitled in
case of any breach by LESSEE of any provision of this lease. This provision,
however, shall not be deemed a waiver of LESSEE's right to insist upon an
election of remedies by LESSOR where otherwise required by law.

      19.3  The failure of LESSOR to insist in any one or more cases upon the
strict performance of any of the terms, covenants, conditions, provisions or
agreements of this lease or to exercise any option herein contained shall not be
construed as a waiver or a relinquishment for the future of any such term,
covenant, conditions, provision, agreement or option. A receipt and acceptance
by LESSOR of performance of anything required by this lease to be performed,
with the knowledge of the breach of any term, covenant, provision or agreement
of this lease, shall not be deemed a waiver of such breach, nor shall any such
acceptance of rent in a lesser amount than herein provided for (regardless of
any endorsement of any check, or any statement in any letter accompanying any
payment of rent) operate or be construed either as an accord and satisfaction or
in any manner other than as payment on account of the earliest rent then unpaid
by LESSEE, and no waiver by LESSEE of any term, covenant, conditions, provision
or agreement of this lease shall be deemed to have been made unless expressed in
writing and signed by LESSOR.

      19.4  In addition to the other remedies in this lease provided, LESSOR
shall be entitled to obtain an injunction against any violation or attempted to
threatened violation, of any of the terms, covenants, conditions, provisions or
agreements of this lease.

      19.5  This lease may not be changed orally, but only by agreement in
writing signed by the party against whom enforcement of the change, modification
or discharge is sought or by his agent.

20    ESTOPPEL CERTIFICATE

      LESSEE agrees, at any time and from time to time, upon not less than ten
(10) days prior request by the LESSOR to execute, acknowledge and deliver a
statement in writing certifying that this lease is unmodified and in full force
and effect (or if there have been modifications that the same is in full force
and effect as modified and stating the modification), and the dates to which the
rent and other charges have been paid in advance, and if there are any defaults
or rent abatements or offsets claimed, it being intended that any such statement
delivered pursuant to this paragraph may be relied upon by the LESSOR, any
prospective

<PAGE>

purchaser of the fee or mortgagee or assignee of any mortgage upon the fee of
the Leased Premises.

21    SUBORDINATION

      This lease is and shall be subject and subordinated to the lien of any
mortgage or mortgages on or affecting the Leased Premises, or any part thereof,
at the date hereof, and to any mortgage or mortgages hereafter made affecting
the Leased Premises, and to all renewals, modifications, consolidations,
replacements or extensions thereof, irrespective of the time of recording such
mortgage provided, however, that the Mortgagee agrees not to disturb LESSEE's
occupancy so long as LESSEE performs its obligations under this Lease. The
provisions of this subordination shall be self-operative, but in confirmation of
this subordination LESSEE shall, at LESSOR's, or mortgagee's request, execute
and deliver such further instruments as may be reasonably desired by the holders
of said mortgages, if any, and LESSEE hereby appoints LESSOR its irrevocable
attorney-in-fact to execute and deliver any such instruments for LESSEE.

22    SHORT FORM LEASE

      The LESSEE will at any time at the request of LESSOR, execute duplicate
originals of an instrument in recordable form which will constitute a short form
or memorandum of lease, setting forth a description of the Leased Property, the
term of lease and oother portions hereof except the rent provisions, that LESSOR
may reasonably request, provided same expressly states that it is subject to,
and is not in any respect a modificationof, this Lease Agreement.

23    SECURITY INTEREST

      LESSEE acknowledges that a security interest has been granted by the
LESSOR on certain monies due or to become due under this Lease. The original
counterpart of the Lease shall be marked "Secured Party's Original" and all
other counterparts thereof shall be marked "Duplicate" and no security interest
can be created except by possession of the original counterpart.

24    LIMITATION OF LIABILITY

      LESSOR shall be under no personal liability with respect to any of the
provisions of this lease, and if it is in breach or default with respect to its
obligations or otherwise, under this lease, LESSEE shall look solely to the
equity of LESSOR in the Leased Property including the proceeds and profits
therefrom for the satisfaction of LESSEE's remedies. It is expressly understood
and agreed that LESSOR's liability under the terms, covenants, warranties and
obligations of this lease shall in no event exceed the amount of its equity in
the Leased Property.

25    ENCUMBRANCES

      The LESSEE shall not cause any of the Leased Property to be encumbered
with any lien, mortgage, security or any other encumbrances during the term of
this lease or any renewal thereof, nor shall the LESSEE have the right to
mortgage its interest in this lease. The LESSOR, however, shall have the
absolute right to mortgage the Leased Property without notice to the LESSEE and
the LESSEE agrees to subordinate this lease or any renewal thereof to the lien
of any mortgage or mortgages on or affecting the Leased Property or any part
thereof, in accordance with paragraph 21 hereof.

26    BROKERS

<PAGE>

      LESSEE hereby represents that no broker was dealt with in connection with
the lease and agrees to indemnify the LESSOR against any and all claims for a
brokerage commission by any person or entity claiming to have dealt with LESSEE.

27    NOTICES

      All notices to be given hereunder shall be in writing, personally
delivered or deposited in the United States mail, certified or registered, with
postage prepaid, and addressed, to the party at the address on page 1 hereof or
such other address as designated in writing by a party hereto. Notices shall be
deemed given when so personally delivered or when deposited in the United States
mail as above provided, with a copy, if to LESSOR to:

<PAGE>

              Mason & Mason, PC
              Law Offices
              394 Old Country Rd.
              Garden City, NY   11530
              ATTN: Michael Mason, Esq.
              Phone:(516) 739-3090
              Fax: (516) 739-3077

If to LESSEE:

              PRYOR CASHMAN SHERMAN & FLYNN
              410 PARK AVE
              NEW YORK NY 10022
              Attn: Eliezer Hecht, Esq.
              (212) 421-4100

              With a Copy to :
              Gregory L. Weaver
              Chief Financial Officer
              3450 Monte Villa Parkway
              Bothell, WA 98021-8906
              (425)908-3615

28    CAPTIONS

      The paragraph captions are for convenience only and shall not limit or be
deemed to construe or interpret the terms and provisions hereof.

29.   APPLICABLE LAW

      This lease and any dispute arising hereunder shall be construed and
enforced in accordance with the laws of the State of New York.

30    SUCCESSORS

      Subject to the provisions of paragraph 13 hereof, this lease shall be
binding upon and inure to the benefit of the heirs, executors, administrators,
successors and assigns of the parties hereto.

31.   ENTIRE AGREEMENT

      This instrument constitutes the entire agreement between the parties
hereto and there are no verbal or collateral understandings, agreements,
representations, or warranties not expressly set forth herein.

32.   Original Lease

      Lessor and Lessee are parties to a lease for the Leased Premises dated
April 23, 1995 (the "Original Lease"). The parties hereby agree that, upon the
the effective date of this Lease, the Original Lease shall terminate in its
entirety and be of no further force and effect.

33.   Tenant Early Termination Right

      Anything herein to the contrary notwithstanding, provided the Lessee is
not in default under any term, covenant or condition of this lease, including
but not limited to the obligation to pay rent, at any time after the expiration
of the third year from the commencement

<PAGE>

date of this lease, Lessee shall have the right to terminate the Lease upon six
(6) months written notice to Lessor (the "Termination Period"). At the end of
the Termination Period, Lessee shall vacate the Lease Premises and this Lease
shall terminate and be of no further force and effect, as though the end of the
Termination Period was the original expiration date of the Lease.

34.   RESTORATION AT LEASE END

      At the expiration of this lease, or sooner termination hereof, LESSEE
shall remove those alterations, additions or improvements, and restore those
portions of the premises, as required in Article 10 herein. LESSEE shall also
remove those alterations, additions or improvements WHICH WERE INSTALLED AFTER
THE DATE OF THIS LEASE, and restore those portions of the premises, for which
consent was required under this lease, but not obtained.

ATTEST:

David A. Yarom, LESSOR

By /s/ David A. Yarom
   ------------------
      DAVID A. YAROM

Dated: March 25, 2005

ATTEST:

Nastech Pharmaceutical Company Inc.

BY: /s/ Gregory L. Weaver
   ----------------------

Dated: March 16, 2005

<PAGE>

DAVID A. YAROM.
                                      with
                       NASTECH PHARMACUTICAL COMPANY INC.

                                  RENT SCHEDULE

a) $83,400.00 base rent for the period July 1, 2005 through June 30, 2006,
payable in advance on the first day of each calendar month in equal monthly
installments of $6,950.00 each.

b) $87,600.00 base rent for the period July 1, 2006 through June 30, 2007,
payable in advance on the first day of each calendar month in equal monthly
installments of $7,300.00 each.

c) $92,000.00 base rent for the period July 1, 2007 through June 30, 2008,
payable in advance on the first day of each calendar month in equal monthly
installments of $7,666.67 each.

d) $96,600.00 base rent for the period July 1, 2008 through June 30, 2009,
payable in advance on the first day of each calendar month in equal monthly
installments of $8,050.00 each.

e) $101,400.00 base rent for the period June 1, 2009 through June 30, 2010,
payable in advance on the first day of each calendar month in equal monthly
installments of $8,450.00 each.

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