Document:

Exhibit 10.7

 

CONFIDENTIAL TREATMENT REQUESTED UNDER RULE 406 UNDER THE
SECURITIES ACT OF 1933, AS AMENDED.

 

[*] INDICATES OMITTED MATERIAL THAT IS THE SUBJECT OF A CONFIDENTIAL
TREATMENT REQUEST FILED SEPARATELY WITH THE COMMISSION. THE OMITTED MATERIAL HAS BEEN FILED SEPARATELY WITH THE COMMISSION.

 

UNANIMOUS SHAREHOLDERS AGREEMENT

 

This Agreement dated as of the 27th day
of March, 2014.

 

AMONG:

 

ADVANCED ACCELERATOR APPLICATIONS
CANADA INC., a corporation incorporated under the laws of Canada

 

(Hereinafter called “AAA Holdco")

 

OF THE FIRST PART;

 

- and-

 

4549694 CANADA INC., a corporation
incorporated under the laws of Canada

 

(Hereinafter called “Exchangeco")

 

OF THE SECOND PART;

 

- and-

 

7329563 CANADA INC., a corporation
incorporated under the laws of Canada

 

(Hereinafter called “Atreus Holdco")

 

OF THE THIRD PART;

 

- and-

 

ATREUS PHARMACEUTICALS
CORPORATION, a Corporation incorporated under the laws of Canada

 

(Hereinafter called the "Corporation")

 

OF THE FOURTH PART.

 

    	 

    	 

    

  

WHEREAS:

 

		1.	The authorized capital of the Corporation consists of an unlimited number of common shares, of
which 1,000 common shares are issued and outstanding and held by the shareholders set out in Schedule A hereto;

 

		2.	The parties wish to enter into this Agreement to provide for the conduct of the business and affairs
of the Corporation, to provide for restrictions on the transfer and ownership of their shares of the Corporation and to govern
their relationship as shareholders of the Corporation.

 

NOW THEREFORE THIS
AGREEMENT WITNESSES THAT, in consideration of the mutual covenants and agreement herein contained and other good and valuable
consideration, the parties hereto agree as follows:

 

ARTICLE 1

 

INTERPRETATION

 

		1.1	Definitions

 

Unless the subject matter or context otherwise
requires:

 

		(a)	"Act" means the Canada Business Corporations Act and any statute that may be substituted therefore, as from
time to time amended, and the regulations thereto and any regulations that may be substituted therefore, as from time to time amended;

 

		(b)	"Affiliate" has the meaning assigned to such term in the Act;

 

		(c)	"thisAgreement"the"Agreement","hereto","hereof',"herein","hereby","hereunder"
and similar expressions mean or refer to this Agreement as amended , from time to time, any indenture, agreement or instrument
supplemental or ancillary hereto or in the implementation hereof, and the expressions "Section", "subsection"
and "paragraph" followed by a number or letter refer to the specified section, subsection or paragraph of
this Agreement;

 

		(d)	"Annual Budget" means the detailed financial
and cash budget of the projected businessactivities and operations of the Corporation, including estimates of proposed and
committed operating and capital expenditures and the subject matter of each expenditure and all sources of revenue, cash
and financing of the Corporation for the subject period;

 

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		(e)	"Articles” means the articles of incorporation
                                         of the Corporation, as amended from time to time;

 

		(f)	"Board of Directors” means the board of directors of the Corporation which shall be constituted in accordance
with the provisions of subsection 2.2 hereof

 

		(g)	"Business Day" means any day other than a Saturday, Sunday or statutory holiday in the Province of Ontario
or France;

 

		(h)	"Common Shares" means the common shares in the capital of the Corporation and any other shares that may henceforth
be issued having the same rights, privileges and restrictions as such common shares;

 

		(i)	"Control” has the meaning assigned to such term
                                         in the Act;

 

		(j)	"Fiscal Year" means the fiscal year of the Corporation which ends on December31 in each year;

 

		(k)	"Milestone" means the Corporation obtaining the IND by the FDA to proceed with a clinical trial with Tc-Annexin,
for the indication on Rheumatoid Arthritis;

 

		(1)	"Person" means any individual, company, corporation, partnership, firm, trust, sole proprietorship, government
or entity howsoever designated or constituted;

 

		(m)	"Public Offering" means an underwritten
public offering of its Common Shares pursuant to a registration statement that has been declared effective under the UnitedStates
Securities Act of 1933 or a prospectus filed under applicable Canadian securities laws in respect of which a (final) receipt has
been obtained, accompanied by the listing of the Common Shares on the Toronto Stock Exchange and/or the Nasdaq National Market
and/or the New York Stock Exchange and/or any other stock exchange or market approved by Special Shareholder Approval;

 

		(n	"Share" means any share in the capital of the Corporation;

 

		(0)	"Shareholder” means any party to this Agreement who is a holder of Shares; and

 

		(p)	"Special Shareholder Approval" means the approval of the holders of Shares representing not less than sixty-six
and two-thirds percent (66 2/3%) of the votes attaching to the outstanding shares in the Corporation.

 

		1.2	Schedules

 

The following are the
schedules attached to and forming part of this Agreement

 

 Schedule A - Shareholders
and Issued Capital of the Corporation

 

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		1.3	Extended Meanings

 

Words importing the singular
number include the plural and vice versa and words importing the masculine gender include the feminine and neuter genders and vice
versa.

 

		1.4	Interpretation Not Affected by Headings

 

The division of this Agreement
into sections and insertion of headings are for convenience of reference only and shall not affect the construction or Interpretation
of this Agreement.

 

		1.5	Applicable Law

 

This Agreement shall be interpreted
in accordance with and be governed by the laws of Ontario and the laws of Canada applicable therein.

 

		1.6	Entire Agreement

 

This Agreement constitutes the
entire agreement among the parties with respect to the subject matter hereof and contains all the representations, undertakings
and agreements of the respective parties.

 

		1.7	Funds

 

All dollar amounts referred to in this Agreement are
in the lawful money of the United States of America.

 

		1.8	Paramountcy

 

If any provision of this Agreement
conflicts with the Articles or by-laws of the Corporation or any agreement among the Corporation and/or any of the Shareholders
and/or any officers or directors of the Corporation concerning matters which are the subject matter of this Agreement, the provisions
of this Agreement shall prevail.

 

		1.9	Invalidity

 

If any provision of this Agreement
shall be held invalid or unenforceable in any jurisdiction, such invalidity or unenforceability shall attach only to such provision
such jurisdiction and shall not in any manner affect or render invalid or unenforceable such provision 111 any other jurisdiction
or any other provision of this Agreement in any jurisdiction.

 

		1.10	Calculation of Time

 

Where in this Agreement a period
of time is given for the doing of any act following the giving of a notice the date on which the notice is given shall be excluded
from the calculation of the time period. When any period of time for the performance of any act expires on a Saturday, Sunday or
a national statutory holiday the period shall be deemed to expire on the next following Business Day. Notwithstanding anything
herein contained to the contrary, the Corporation shall have the right, at its sole option, to postpone any date provided for herein
to a date not exceeding three Business days after such date.

 

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		1.11	Privity

 

This Agreement shall be binding
upon all Persons executing these presents, and all Persons who subsequently become holders of Shares, each of whom shall execute
a counterpart of this Agreement. Any agreement to be bound hereby and any other agreement among the parties hereto with respect
to the Corporation or the Shares may be effectively delivered by one party to each of the others by delivery of an executed counterpart
of this Agreement to the Corporation.

 

ARTICLE 2

 

CONDUCT OF THE AFFAIRS OF THE CORPORATION

 

		2.1	Business and Affairs of the Company

 

The Shareholders shall cause
such meeting to be held, votes to be cast, resolutions to be passed, by-laws to be made and confirmed, documents to be executed
and all other things and acts to be done to ensure that, at all times, the following provisions are in effect or are complied with,
or with respect to any provision which is not entirely within the control or power of the Shareholders to cause compliance therewith,
the Shareholders .shall use their best efforts to cause such compliance to occur.

 

		2.2	Directors of the Corporation

 

(a)     The
Shareholders, by majority vote, will determine from time to time the number of directors to be elected.

 

(b)    The
Shareholders will from time to time so act and vote (to the extent that each is able to do so on account of its respective shareholdings
or otherwise) so that the board of directors (the "Board") of the Corporation shall consist of at least one nominee of
AAA Holdco and at least one nominee of Atreus Holdco; provided that, such right shall terminate in respect of each such Shareholder
if AAA Holdco and Exchangeco, on the one hand, or Atreus Holdco, on the other hand, shall cease to hold Shares in the capital of
the Corporation representing at least 5% of the votes attaching to the outstanding shares in the Corporation.

 

(c)    Each
of AAA Holdco and Atreus Holdco shall be entitled at any time to require the removal of any director nominated by it and to provide
for a successor nominee by written notice to the Corporation and to the other Shareholders. No Shareholder other than a shareholder
having nomination rights shall use its voting rights to remove a director who is a nominee of AAA Holdco or Atreus Holdco. If a
director nominated by AAA Holdco or Atreus Holdco ceases to be a director for any reason, the Shareholders shall, if necessary,
fill the

 

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vacancy thereby created by appointing,
as soon as reasonably possible, the individual who is nominated by AAA Holdco or Atreus Holdco, as the case may be.

 

(d)     A
quorum for a meeting of directors of the Corporation shall be a nominee of each of the Shareholders; provided that, if a nominee
is not able to attend two (2) successive properly called board meetings, then the next meetings may proceed without such nominee
being present, so long as a majority of directors are present.

 

(e)    Notice
of meetings of the Board shall be accompanied by an agenda together with copies of documents to be considered at such meetings.
AAA Holdco and Atreus Holdco shall make best efforts to convene board meetings at least [quarterly] during the year. Each of AAA
Holdco and Atreus Holdco may bring one observer to board meetings, but such observer shall have no right to vote. Any additional
observers shall require the approval of the other board members.

 

(f)    The
Board shall appoint a Chairperson (who shall not have a casting vote in the event of an equality of votes on any matter among members
of the Board), who shall initially be ■.

 

		2.3	Directors' Compensation and Indemnity

 

The Corporation will pay all
reasonable out-of pocket expenses incurred by the directors to attend meetings of the Board of Directors. Directors shall be indemnified
by the Corporation with respect to their actions as directors to the maximum extent, and subject to the limitations, permitted
by law. The Board will determine what, if any, compensation will be paid to any external director

 

		2.4	Shareholders' Right of Inspection and Inquiry

 

The Corporation shall permit
Persons designated by the Shareholders to visit and inspect any properties of the Corporation, to examine the books and financial
records of the Corporation and to discuss with management its affairs, finances and accounts all during normal business hours and
as often as may be reasonably requested, with prior notice and at times reasonably convenient to management. The Persons designated
pursuant to this provision may include accountants (including the auditors of the Corporation) or management consultants or
others appointed to examine all or any aspect of the operations of the Corporation, and the Corporation agrees to cause management
to answer fully and fairly and to the best of their ability any reasonable inquiries which such Persons may have. The Corporation
agrees that such Persons may, in the course of their investigations, discuss the business and affairs of the Corporation with the
officers and directors and with the auditors of the Corporation.

 

		2.5	Annual Financial Statements

 

Within 90 days after the end
of the Fiscal Year, the Corporation shall prepare and furnish or cause to be prepared and furnished to the Shareholders unaudited
consolidated financial statements in respect of the Corporation, including a balance sheet and statements of changes in financial
position and profit and loss, together with a comparison of the actual

 

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budgeted results, each of the end of such Fiscal Year and
prepared in accordance with Canadian generally accepted accounting principles applied on a consistent basis from time to time and
certified by the President of the Corporation. The Shareholders agree to waive the right to receive audited financial statements
as permitted in the Act; provided however, that a Shareholder may retract such waiver in respect of a fiscal year of the Corporation
and prior to the commencement of such fiscal year if (i) such Shareholder agrees to pay the full incremental costs of conducting
such audit; and (ii) such audit can be completed without unduly interfering with the business operations of the Corporation.

 

		2.6	Additional Financial Reporting

 

The Corporation shall provide
the Shareholders with the following data:

 

(a)     Quarterly
financial report, within 30 days of the end of each calendar quarter;

 

(b)     6
months balance sheet, income statement and cash flow statement for the Corporation, its Subsidiaries and on a consolidated basis,
within 40 days after the end of each semester; and

 

(c)     budget
for the year including income statement balance sheet and cash flow statements and capital expenditure plans of the Corporation,
its subsidiaries and on a consolidated basis, within thirty (30) days of the end of each fiscal year of the Corporation.

 

		2.7	Board of Directors Consent/Special Shareholder
Approval Respecting Certain Matters

 

Save and except as expressly
provided in this Agreement, no action shall be taken by the Corporation in respect of any of the matters described below without
prior Special Shareholder Approval, which approval shall be in addition to any other approvals that may be required by the
Act;

 

(a)     the
approval of the Corporation's annual budget;

 

(b)     any
significant deviation from the Corporation's current business plan;

 

(c)     any
redemption or repurchase of Shares not effected on a pro-rata basis.

 

		2.8	Licensing of IP Almexin rights in the USA and Japan

 

Any decisions with respect to
the licensing of IP Annexin rights in the USA and Japan shall be on terms determined by Atreus Holdco; provided that:

 

(i)     Atreus
Holdco shall consult with AAA Holdco prior to any such agreement being entered into;

 

(ii)     Atreus
Holdco shall provide an execution copy of the proposed license agreement to AAA Holdco not less than fifteen (15) days prior to
the execution of any such agreement, during which time AAA Holdco shall have the right to provide a written opinion thereon which
shall be considered in good faith by Atreus Holdco; and

 

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(iii)     The
terms of such license agreement shall be commercially reasonable and consistent with the fiduciary obligations of the directors
of the Corporation.

 

ARTICLE 3

 

RESTRICTIONS ON TRANSFER OF SHARES

 

		3.1	Restrictions on Transfer of Shares

 

No Shareholder shall, except
as expressly provided herein, directly or indirectly, sell assign or otherwise transfer or encumber by pledge, assignment, mortgage,
charge or otherwise, any Shares from time to time held by it. Any attempted sale, assignment, transfer or other disposition of
Shares in violation of this Agreement shall be void and of no force and effect and the Corporation shall not recognize any such
attempted disposition.

 

A transfer of a controlling interest
in AAA Holdco or Atreus Holdco shall be subject to the provisions of this Article 3.

 

		3.2	Pledge of Shares

 

Each of the Shareholders may
mortgage, hypothecate, pledge or charge its Shares to a commercial lending institution as security for an operating or term loan
provided by that institution to the Corporation, provided that each of the Shareholders consents in advance to such transaction
and provided further that the Person to whom such Shares are mortgage, hypothecated, pledge or charged agrees in writing to be
bound by the provision of this Agreement with respect to such Shares and, in the event of the realization on such Shares, such
Person shall become a party to this Agreement.

 

		3.3	Permitted Transfers

 

Notwithstanding the terms of
this Agreement, a Shareholder shall be entitled to sell, assign, transfer or otherwise dispose of all or any shares in the capital
of the Corporation beneficially owned by such Shareholder to an Affiliate, provided that, prior to the completion of such sale,
assignment, transfer or other disposition, the transferee agrees to be bound by the terms of this Agreement.

 

		3.4	Piggyback/ Drag-Along

 

		(a)	Offer - If an independent third party (the "Third
Party") shall make a bona fide offer (the "Offer") to purchase all or a majority of the Shares of the
Corporation which the holders of not less than sixty-six and two-thirds (66 2/3rds) of the Shares (the "Super Majority")
wish to accept, then, the Super Majority shall give notice (the "Notice of Sale") to the other Shareholders (the
"Other Shareholder(s)") specifying therein the number of Shares which Super Majority desires to sell (the "Offered
Shares") and the terms upon which and the price at which it desires to sell the Offered Shares, including the identity
of the proposed purchaser (the "Selling Price").

 

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		(b)	Rejection, Third Party Sale and Piggyback - The Super Majority may, at any time and from
time to time during the period of 90 days next following the delivery of the Notice of Sale, sell the Offered Shares to the Third
Party at a price which is not less than the Selling Price and on terms not less favourable to the Super Majority than those set
out in the Notice of Sale, provided that the Third Party shall have offered by notice given to each of the Other Shareholders to
purchase from each of the Other Shareholders all the Shares owned by such of the Other Shareholders at the price and upon the terms
and conditions set forth in the offer from the Third Party.

 

		(c)	Time for Sale - If the Super Majority does not effect a sale to the Third Party during the
90-day period referred to in paragraph (b), then the foregoing provisions hereof shall again apply thereto and so on from time
to time.

 

		(d)	Drag-Along - In the event that any of the Other Shareholders do not wish to accept the Third
Party offer under paragraph (b) above, the Super Majority may, if the Third Party Offer is an offer to acquire all of the Shares,
by notice in writing given to the Other Shareholders who do not wish to sell at any time ten (l0) days or more prior to the expiry
of the Offer, require the Other Shareholders to sell their Shares pursuant to the Offer at the same price specified in the Offer:

 

Notwithstanding the foregoing,
no Shareholder is required to comply with the terms of this Section 3.4 if:

 

		(i)	consideration under the Offer is not payable in cash or securities of a publicly traded entity
(or shares exchangeable into shares of a publicly traded entity);

 

		(ii)	the liability of such Shareholder under the purchase agreement in respect of the Offer (including,
without limitation, liability for a breach of representation or warranty or for a claim under an indemnity) exceeds with respect
to such Shareholder the lesser of such Shareholder's (A.) pro rata share of any claim; and (B,) the purchase price payable to such
Investor; or

 

		(iii)	any representation and warranty to be given by a Shareholder is to be given on a joint and several
basis.

 

		(e)	Power of Attorney - Each of the Other Shareholders hereby appoints, in the event that circumstances
give rise to this Section 3.4, the President of the Corporation as the Shareholder's attorney, with full power of substitution,
in the name of the Shareholder, to execute and deliver all deeds, transfers, assignments and assurances necessary to effectively
transfer the interest being sold in the Corporation under this Section 3.4.Such appointment, being coupled with an interest, is
irrevocable by each 

 

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Shareholder and shall not
be revoked by the insolvency, bankruptcy, death incapacity, dissolution, liquidation or other termination of the existence of the
Shareholder and the Shareholder agrees to ratify and confirm all that the Corporation may do or cause to be done pursuant to the
foregoing. The Shareholder consents to any transfer of shares made pursuant to the foregoing.

 

		3.5	Right of First Refusal

 

		(a)	Unless the provisions of Section 3.4(d) apply, in the
event that any Shareholder (hereinafter in this Section 3.5 referred to as the "Selling Shareholder") receives
a bona fide offer from a person, firm or corporation dealing at arm's length with such Shareholder (including another Shareholder)
(hereinafter in this Section 3 referred to as the "Offer") to purchase any or all of the Shares owned or
controlled by the Selling Shareholder, which the Selling Shareholder is prepared to accept, then the Selling Shareholder shall
forthwith give to the Corporation and to each of the other Shareholders who owns more than one percent (1%) of the outstanding
Common Shares (hereinafter in this Section 3.5 referred to as the "Offeree Shareholders") notice in writing of
its desire or intention to sell such Shares accompanied by a copy of the entire Offer which, without limiting the generality of
the foregoing, shall fully identify the offeror.

 

		(b)	Such notice shall provide that the Corporation shall
be entitled to purchase any or all of the offered Shares and each Offeree Shareholder shall be entitled to purchase such number
of the offered Shares not purchased by the Corporation as nearly as may be in proportion to the number of Shares of the class
of offered Shares held by it at the date of the Offer on the same terms as specified in the Offer and shall also state that any
Offeree Shareholder who desires to purchase a number of Shares so offered in excess of its proportion shall in its reply state
how many Shares in excess of its proportion it desires to purchase. Such notice shall also provide that if the Corporation or
Offeree Shareholder do not accept such offer from the Selling Shareholder within thirty (30) days after the date of notice of
the Offer, it will be deemed to have been declined. The Corporation shall notify the Selling Shareholder and each Offeree Shareholder
within fifteen (15) days of receipt of notice of the Offer whether it intends to purchase any of the Shares.

 

		(c)	If all the Offeree Shareholders do not claim their respective proportions, the unclaimed Shares
so offered shall be used for satisfying the claims of Offeree Shareholders for Shares in excess of their proportions and if the
claims in excess are more than sufficient to exhaust such unclaimed Shares, the unclaimed Shares shall be divided pro rata among
the Offeree Shareholders desiring excess Shares in proportion to their existing holdings of Shares of the class of offered Shares;
provided that no Offeree Shareholder shall be bound to take any Shares in excess of the amount which it desires.

 

		(d)	If any Shares shall not be capable of being offered to or divided among the Offeree Shareholders
in proportion to their existing holdings of Shares without

 

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division into fractions of shares,
the same shall be offered to or divided among the Offeree Shareholders as nearly as may be in proportion to the number of Shares
of the class of offered Shares held by them respectively at the date of such Offer as may be determined by the Board.

 

		(e)	If by the time limited by the Offer, the Corporation
and the Offeree Shareholders have not agreed to purchase all the Shares offered thereby on the terms specified in the Offer, the
Selling Shareholder shall be under no obligation to sell any Shares to the Corporation and the Offeree Shareholders or any of
them and the Selling Shareholder may, within ninety (90) days from the date of the Offer, sell all and not less than all of the
Shares specified in the Offer pursuant to the provisions of this Section 3.5 to the bona fide purchaser at a price not less than
the share price set out in the Offer and on the other terms and conditions set out in the Offer; provided that such person or
persons to whom the Selling Shareholder sells the Shares, contemporaneously with the purchase of such Shares, shall covenant and
agree with all the other Shareholders to be bound by the terms and conditions of this Agreement as if it were an original party
thereto by signing an acknowledgment to become bound by the terms of this Agreement. After the expiration of the said ninety
(90) days, no sale of Shares shall be made except without again complying with the provisions of this Section 3.5.

 

ARTICLE 4

 

ADDITIONAL ISSUE OF SHARES

 

		4.1	Pre-Emptive Right

 

Subject to the provisions of
Section 4.2 hereof, in the event the Corporation wishes at any time to issue any Shares (except for the granting of options to
employees not to exceed 10% of the issued and outstanding shares of the Corporation) it shall offer them for purchase by the Shareholders
by notice given to each Shareholder. Such notice shall be given within 10 days of the approval of the Board of Directors of a proposal
to issue Shares to raise funds and shall set forth a description of the Shares to be offered, the purchase price and the purchase
date which shall be a date not earlier than twenty (20) days after the date of such notice. Upon receipt of such notice, each such
Shareholder shall have the right to subscribe for and purchase a number of such Shares determined by multiplying the total
number of Share offered by a fraction, the numerator of which shall be the number of Common Shares owned by such Shareholder at
the date of such notice and the denominator of which shall be the total number of Conunon Shares outstanding as at the date of
such notice. Such right shall be exercised by the Shareholder by giving notice of acceptance to the Corporation within twenty (20)
days after the receipt of the notice from the Corporation. In the event that the Shareholder does exercise such right it shall
subscribe, purchase and pay for such Shares on the purchase date set forth in the notice of the Corporation. If all the Shareholders
do not subscribe for their respective proportions, the unsubscribed Shares shall be used to satisfy the subscriptions of such Shareholders
for Shares in excess of their proportion and,

 

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if the subscriptions in excess are more than sufficient to exhaust such unsubscribed
Shares, the unsubscribed Shares shall be divided pro rata among the Shareholders desiring Shares as nearly as may be in proportion
to the number of Common Shares held by them respectively at the date of such notice, but no Shareholder shall be bound to take
any such Shares in excess of the amount it desires. It shall be a condition to the issuance of any new shares that the new Shareholder
become party to this Agreement or, if agreed by the Board, another shareholder or share restriction agreement approved by the Board.

 

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		4.2	Right of AAA Holdco to Increase Shareholdings

 

Notwithstanding the provisions
of Section 4,1 hereof, and provided AAA Holdco and Exchangeco together own more than 50% of the Shares in Atreus and have no obligation
to return Shares to the Corporation that would leave it with less than 50% of the Shares, AAA Holdco shall have the right, exercisable
by a written offer to the Corporation, with a copy to Atreus Holdco, any time after the day which is eighteen (18) months after
the date of this Agreement, to subscribe for such number of additional Common Shares to permit it to reach up to a 65% shareholding
in the Corporation, at a price per share determined in AAA Holdco's sole discretion (the "AAA Holdco Offer").
In case such an offer is made in writing to the Corporation, the Corporation, and Atreus Holdco, shall have the right to find investors
to subscribe to substantially the same amount of shares that are the subject matter of the AAA Holdco Offer at a price [*] higher
than the price offered by AAA Holdco (the "Higher Price"), within [*] months from receipt by the Corporation of
the AAA Holdco Offer. Atreus Holdco shall be permitted to disclose relevant information about the Corporation to prospective investors
considering making an investment in the Corporation based on the AAA Holdco Offer, subject to the execution of a confidentiality
and non-disclosure agreement in a form approved by AAA Holdco.

 

In case one or more investors
place a bona fide binding offer at a Higher Price as set out above within the above mentioned [*] months period, then the investors'
offer will be deemed accepted and the offering investor shall have the obligation to subscribe to the offered shares at a Higher
Price and AAA Holdco shall have the right, but not the obligation, to subscribe to the same amount of shares that are the subject
matter of the AAA Holdco Offer, at the Higher Price. In any case, AAA Holdco shall have the right to subscribe for additional shares
at the Higher Price in order to maintain majority.

 

In case the Corporation and Atreus
Holdco do not find other investors within the above mentioned [*] months period, then AAA Holdco shall have the right to complete
the AAA Holdco Offer within [*] ([*]) days after the expiry of such [*] month period, and the Corporation shall fully cooperate
in order to complete such transaction.

 

ARTICLE 5

 

PAYMENT AND CLOSING PROVISIONS

 

		5.1	Payment and Closing Provisions

 

In the event of the sale of Shares
as provided in Article 3 hereof, the party selling shall in this subsection 5.1 be called the "Vendor" and the
party purchasing shall be in this subsection 5.1 be called the "Purchaser" and the following provisions shall apply:

 

Certain confidential information has been omitted from this
document, as indicated by the notation “[*]”. The omitted information has been filed on a confidential basis with the
Securities and Exchange Commission pursuant to a request for confidential treatment.

 

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(a)     Payment
of Purchase Price and Delivery of Certificates - The purchase price shall be paid in such a manner as the Vendor and the Purchaser
may agree or as specified pursuant to the relevant provision of this Agreement, as the case may be, against receipt by the Purchaser
of the share certificate or certificates representing the Shares being purchased and sold, duly endorsed in blank for transfer
together with signed and dated resignations by the Vendor or its nominee as a director and officer of the Corporation.

 

(b)     Closing
- closing shall take place at 10:00 a.m. on the closing date at the office of the solicitors for the Corporation.

 

(c)     Title
- The Vendor shall warrant that it has good and marketable title to the Shares being sold subject only to the terms of this Agreement,
and shall deliver to the Purchaser all such documents, instruments and releases and shall take all such steps and do all such acts
and things as may be necessary or desirable to vest title in the Shares to the Purchaser and the Purchaser shall be bound by all
the terms of this Agreement as if he had been a party hereto.

 

(d)     Failure
to Complete Sale - If on the date of closing the Vendor shall have failed, neglected or refused to complete the sale, the
Purchaser shall have the right to deposit the purchase price for the account of the Vendor in the Corporation's bank and thereafter
to execute and deliver such deeds, transfers of share certificates, resignations, releases and other documents that may be necessary
or desirable in order to complete the transaction with respect to such purchase; and the Purchaser is hereby irrevocably constituted
and appointed as the attorney of the Vendor to so execute and deliver.

 

(e)     Vendor
Indebted to Corporation - If at the time of such sale the Vendor shall be indebted to the Corporation, the Purchaser shall
at the Vendor's option pay, satisfy and discharge suchindebtedness out of the purchase price payable for the Shares.

 

(f)     Assignment
of Indebtedness - If at the time of sale the Corporation shall be indebted to the Vendor, the Purchaser shall, at the Vendor's
option, upon the closing of such sale, purchase from the Vendor that proportion of the indebtedness that the number of Shares to
be sold bears to the total number of Shares held by the Vendor for a price equal to the amount thereof and shall pay such price
to the Vendor on closing by certified cheque against the delivery of a valid assignment to the Purchaser of such indebtedness.
Alternatively, if the Purchaser and the non-selling Shareholders if any agree, the Purchaser may cause the Corporation to repay
such indebtedness or portion thereof to the Vendor.

 

(g)     Liability
as Guarantor  - If at the time of sale, the Vendor shall be liable or responsible as a guarantor for any debts, liabilities
or obligations of the Corporation, the Purchaser shall use its best efforts to cause any and all such guarantees to be released
on or before the date of closing and, in the event that the Purchaser shall be unable to deliver up such guarantees, the Purchaser
shall indemnify and save harmless the Vendor from all claims arising out of such guarantees.

 

    	~ 14 ~

    	 

    

  

(h)    Payment
of Declared Dividends - Prior to the closing of any sale of Shares any declared and unpaid dividends in respect of the Shares
to be sold shall be paid in full to the Vendor

 

ARTICLE 6

 

CONFIDENTIALITY

 

		6.1	Confidentiality

 

For so long as the Corporation carries
on business, each Shareholder shall keep confidential any trade secret, patent, know-how or secret, technical expertise, customer
list or non-public information of any sort relating to the business carried on by the Corporation, as may from time to time be
acquired by it by virtue of being a Shareholder, officer, agent, director or employee of the Corporation, and shall use its best
efforts to prevent communication of such information to others, even after such Shareholder ceases to own, directly or indirectly,
Shares, provided that a party's obligations to disclose information requested pursuant to applicable laws shall supersede its obligations
pursuant to this provision. The provisions hereof are in addition to and not in substitution for any confidentiality agreement
executed by any party hereto.

 

ARTICLE 7

 

GENERAL

 

		7.1	Share Certificates

 

All certificates representing Shares shall
have endorsed thereon the following notation:

 

"The shares represented
by this certificate are subject to the terms of a Shareholders Agreement dated ■ as amended from time to time, among the
shareholders of the Corporation and the Corporation and others. Such shares may not be sold, transferred, pledged, hypothecated
or otherwise disposed of except in accordance with the provisions thereof herewith."

 

		7.2	Assignment and Enurement

 

This Agreement is not assignable
by any party except insofar as its benefit and burden pass with the Shares transferred in accordance with the provisions of this
Agreement. This Agreement shall enure to the benefit of and be binding upon the successors and permitted assigns of the parties
hereto.

 

		7.3	Notices

 

Any instrument, notice, consent, request
or election required or permitted to be given under this Agreement shall be in writing and delivered personally or transmitted
by telecopier or other form of recorded communication or, except in the event of disruption or threatened disruption of postal
service, mailed by prepaid registered mail addressed to the party to whom it is to be given at his address as shown below and such
notice shall be deemed to have been given on the next day after delivery or transmission or on the fourth business day after mailing
as aforesaid, as the case may be,

 

    	~ 15 ~

    	 

    

  

	if to AAA Holdco or Exchangeco:	■	 
	 	 	 
	 	■	 
	 	 	 
	 	Attention:	■
	 	 	 
	 	Fax:	■
	 	 	 
	if to Atreus Holdco: 	■	 
	 	 	 
	 	■	 
	 	 	 
	 	Attention:	■
	 	 	 
	 	Fax:	■
	 	 	 
	if to the Corporation:	 	 
	 	 	 
	 	Attention:	■
	 	 	 
	 	Fax	■

 

Notice of change of address may be given
to any party in the same manner.

 

		7.4	Time of Essence

 

Time shall be of the
essence of this Agreement.

 

		7.5	Further Assurances

 

The parties hereto hereby' agree
to execute or cause to be executed such other documents, instruments and certificates as may be required to effectively carry out
the terms and conditions of this Agreement.

 

		7.6	CounterpaIis

 

This Agreement may be executed
in one or more counterparts each of which shall be deemed to be an original and such counterparts together shall constitute but
one and the same instrument.

 

		7.7	Waivers - In this Agreement:

 

(a)    Not
a Waiver of Other Rights - A waiver by any party of its rights hereunder or of the performance by any other party of any of
its obligations hereunder shall be without prejudice to all or any of the other rights hereunder of the party so waiving and shall
not constitute a waiver of any other such rights or, in any other instances, of the rights so waived or a waiver of performance
by the party of any of its other obligations hereunder or the performance, in any other instance, of the obligations so waived.

 

    	~ 16 ~

    	 

    

  

(b)    In
Writing - No waiver on behalf of any party of the breach of any of the covenants, conditions and provisions herein contained
shall be effective or binding upon such other party unless the same shall be expressed in writing.

 

		7.8	Termination

 

This Agreement terminates
upon the first to occur of:

 

(a)     
the date this Agreement is terminated by the written approval by Shareholders holding at least sixty-six and two-thirds percent
(66 2/3%) of the outstanding shares of the Corporation;

 

(b)     the
date that is immediately prior to a Public Offering by the Corporation;

 

(c)     the
date that the Corporation is wound-up, liquidated or dissolved, whether voluntarily or involuntarily; and

 

(d)     that
date that one Person becomes the beneficial owner of all of the Shares.

 

		7.9	Amendment

 

No amendment, supplement or modification
of this Agreement and, unless otherwise specified, no waiver, consent or approval by any Party, is binding unless approved by the
Board, and approved in writing by Shareholders holding at least sixty-six and two-thirds percent (66 2/3 %) of the outstanding
shares of the Corporation and any amendment, supplement, modification, waiver, consent or approval so approved shall be binding
upon each of the Parties, but only if no Shareholder, without its consent, is materially and adversely affected by any such amendment,
supplement, modification, waiver, consent or approval in any maimer in which the other Shareholders are not likewise adversely
affected.

 

		7.10	Facsimile Delivery

 

This Agreement may be delivered
upon the provision of telefaxed execution pages provided that the party delivering such telefaxed execution pages shall as soon
as practicable thereafter deliver to the other parties an originally executed execution page.

 

[The remainder of this page has been
left blank intentionally}

 

    	~ 17 ~

    	 

    

  

IN WITNESS WHEREOF the parties hereto
have executed this Agreement on the date set out above.

 

	 	ADVANCED ACCELERATOR
	 	 
	 	APPLICATIONS CANADA INC.
	 	 	 
	 	By: 	/s/ Stefano Buono
	 	 	 
	 	Name: 	 Stefano Buono
	 	 	 
	 	Title:	 President

  

 

	 	4549694 CANADA INC.
	 	 	 
	 	By: 	/s/ Stefano Buono
	 	 	
	 	Name:  	Stefano Buono
	 	 	 
	 	Title:	President

  

 

	 	7329563  CANADA  INC.
	 	 
	 	By: 	/s/ William J. Dickie

  

	 	Name: William J. Dickie
	 	 
	 	Title: Director
	 	 	 
	 	ATREUS  PHARMACEUTICALS
	 	 
	 	CORPORATION

  

	 	By: 	/s/ William J. Dickie

  

	 	Name: William J. Dickie
	 	 	 
	 	Title: Director

 

    	~ 18 ~Exhibit 10.8

 

CONFIDENTIAL TREATMENT REQUESTED UNDER RULE 406 UNDER THE SECURITIES
ACT OF 1933, AS AMENDED.

 

[*] INDICATES OMITTED MATERIAL THAT IS THE SUBJECT OF A CONFIDENTIAL
TREATMENT REQUEST FILED SEPARATELY WITH THE COMMISSION. THE OMITTED MATERIAL HAS BEEN FILED SEPARATELY WITH THE COMMISSION.

 

	
         

        SHARE PURCHASE AGREEMENT

         

 

Made as of
December 18, 2014

 

    	 

    	 

    

 

TABLE OF CONTENTS

 

	Article 1 INTERPRETATION	1
	1.1	General Definitions	1
	1.2	Headings, etc.	7
	1.3	Number, etc.	7
	1.4	Currency	7
	1.5	Accounting Principles	7
	1.6	Additional Rules of Interpretation	7
	1.7	Knowledge	8
	1.8	Schedules	8
	1.9	Taxes	8
	Article 2 PURCHASE AND SALE	8
	2.1	Agreement of Purchase and Sale	8
	2.2	Purchase Price	8
	2.3	Payment of Purchase Price	8
	2.4	Determination and Payment of Royalty Amounts	9
	2.5	Anniversary Payments	11
	2.6	Manner of Payments	11
	2.7	Termination	11
	Article 3 REPRESENTATIONS AND WARRANTIES OF THE SELLER AND RELATING TO THE CORPORATION	12
	3.1	Seller’s Representations and Warranties	12
	3.2	Representations and Warranties relating to the Corporation	13
	3.3	Non-Waiver	18
	Article 4 PURCHASER’S REPRESENTATIONS AND WARRANTIES	19
	4.1	Purchaser’s Representations and Warranties	19
	4.2	Non-Waiver	20
	Article 5 INDEMNIFICATION	20
	5.1	Non-Merger and Exclusive Remedy	20
	5.2	Indemnification by Seller	20
	5.3	Indemnification by the Purchaser	20
	5.4	Time Limitations	21
	5.5	Limitations on Amount	22
	5.6	Limited Recourse	22
	5.7	Notice of Third Party Claims	22
	5.8	Defence of Third Party Claims	22
	5.9	Assistance for Third Party Claims	23
	5.10	Settlement of Third Party Claims	23
	5.11	Direct Claims	23
	5.12	Failure to Give Timely Notice	24
	5.13	Set-off	24
	5.14	Reductions and Subrogation	24
	5.15	Tax Effect	24
	5.16	Additional Rules and Procedures	24
	Article 6 CLOSING ARRANGEMENTS	25
	6.1	Date, Place and Time of Closing	25
	6.2	Closing Deliveries of the Seller	25
	6.3	Closing Deliveries of the Purchaser	26

 

    	 

    	 

    

 

	Article 7 GENERAL	26
	7.1	Further Assurances	26
	7.2	Costs and Expenses	26
	7.3	Public Announcements	26
	7.4	Assignment	26
	7.5	Notices	27
	7.6	Governing Law	28
	7.7	Benefit of Agreement	28
	7.8	Amendment and Waiver	28
	7.9	Entire Agreement	28
	7.10	Severability	28
	7.11	Counterparts and Execution by Electronic Means	29

 

    	 	2

    	 

    

 

SHARE PURCHASE AGREEMENT

 

THIS
SHARE PURCHASE AGREEMENT is made as of the 18th day of December, 2014 between 7329563 Canada Inc. (the “Seller”),
a corporation incorporated under the Canada Business Corporations Act, and Advanced Accelerator Applications International
S.A. (the “Purchaser”), a corporation incorporated under the laws of Switzerland and Advanced Accelerator
Applications S.A. (“Parent”), a corporation incorporated under the laws of France.

 

RECITALS:

 

WHEREAS
Atreus Pharmaceuticals Corporation (the “Corporation”) is a corporation incorporated under the Canada
Business Corporations Act;

 

AND
WHEREAS the Seller is the owner of 499 Common Shares in capital of the Corporation (the “Purchased Shares”);

 

AND
WHEREAS members of the Purchaser Group (as hereinafter defined) are the owners of 501 Common Shares in the capital of
the Corporation;

 

AND
WHEREAS the Seller wishes to sell and the Buyer wishes to buy from the Seller the Purchased Shares;

 

AND
WHEREAS the Parties desire to make certain representations, warranties and agreements in connection with the transactions
contemplated by this Agreement;

 

NOW
THEREFORE THIS AGREEMENT WITNESSES that in consideration of the premises and the mutual covenants and agreements herein
contained the Parties hereto covenant and agree as follows:

 

Article 1

INTERPRETATION

 

		1.1	General Definitions

 

In this Agreement (including
the recitals hereto), unless something in the subject matter or context is inconsistent therewith, the following terms have the
following meanings:

 

		(a)	“Accounting Firm” has the meaning set forth in Section 2.4(c);

 

		(b)	“Affiliate” has the meaning given to that term in the Canada Business Corporations
Act;

 

		(c)	“Agreement” means this agreement and all Schedules annexed hereto, as amended
from time to time;

 

		(d)	“Annexin” means all forms of annexin developed and marketed by the Corporation
or, from and after the date hereof, any other member of the Purchaser Group from time to time;

 

		(e)	“Annexin Sales” shall mean, with respect to the applicable period, all gross
revenue actually received by the Corporation and the Purchaser Group

 

    	 

    	 

    

 

(determined on
a consolidated basis) from Annexin, determined in accordance with IFRS, but shall not include the following items (to the extent
that they pertain to the making, using, importing or selling of Annexin, are otherwise included in gross revenue, and are separately
billed):

 

		(i)	import, export, excise and sales taxes, and custom duties;

 

		(ii)	costs of insurance, packing and transportation from the place of manufacture to the customer's
premises; and

 

		(iii)	credit for returns, allowances or trades;

 

		(f)	“Anniversary Payment” has the meaning set forth in Section 2.5;

 

		(g)	“Annual Financial Statements” means the unaudited financial statements of the
Corporation as, at and for the financial year ended December 31, 2013, a copy of which are attached hereto as Schedule “A”;

 

		(h)	“Annual Royalty Amount” has the meaning set forth in Section 2.4(c);

 

		(i)	“Approval Date” means the earlier of the First Milestone Approval Date and the
Second Milestone Approval Date;

 

		(j)	“Benefit Plan” means any plan providing for profit sharing, deferred compensation,
incentives, health, dental, welfare, bonuses, retirement, unemployment compensation, insurance, severance, sick leave or vacation,
or any other employee benefit plan of a similar nature, that is sponsored or maintained by or contributed to or required to be
contributed to by the Corporation for the benefit of any of its employees, former employees or beneficiaries of any of them, whether
or not insured (except, that, the term “Benefit Plan” shall not include any statutory plans with which the Corporation
is required to comply, including the Canada/Quebec Pension Plan or plans administered pursuant to applicable provincial health
tax, workers’ compensation, workers’ safety and insurance or employment insurance legislation);

 

		(k)	“Business” when used in relation to the Corporation means the business of developing
and selling Annexin-based imaging agents;

 

		(l)	“Business Day” means any day except Saturday, Sunday or any statutory holiday
in the Province of Ontario;

 

		(m)	“Claim” means any act, omission or state of facts, and any legal proceeding,
assessment, judgment, settlement or compromise relating thereto, which may give rise to a right to indemnification under Article
5;

 

		(n)	“Closing Date” means the date hereof;

 

		(o)	“Closing Date Payment” means CHF 318,955;

 

    	 	2

    	 

    

 

		(p)	“Closing Time” means 1:00 p.m. in the City of Ottawa on the Closing Date or
such other time on the Closing Date as the Parties may agree in writing that the Closing will take place;

 

		(q)	“Contract” means any written, oral, implied or other agreement, contract, understanding,
instrument, note, guarantee, indemnity, representation, warranty, deed, assignment, power of attorney, certificate, commitment,
covenant, assurance or undertaking of any nature;

 

		(r)	“Corporation” has the meaning set forth in the recitals;

 

		(s)	“Defending Party” has the meaning set forth in Section 5.9;

 

		(t)	“Direct Claim” has the meaning set forth in Section 5.11;

 

		(u)	“Disclosure Schedule” means the schedule of exceptions annexed hereto as Schedule
“C”;

 

		(v)	“EMA” means the European Medicines Agency;

 

		(w)	“Encumbrance” means any mortgage, charge, easement, encroachment, lien, adverse
claim, restrictive covenant, assignment by way of security, security interest of any nature, servitude, pledge, hypothecation,
security agreement, title retention agreement, right of occupation, option or privilege or any agreement to create any of the foregoing;

 

		(x)	“FDA” means the U.S. Food and Drug Administration;

 

		(y)	“Final Fiscal Year” has the meaning set forth in Section 2.4(c);

 

		(z)	“Financial Statements” means, collectively, the Annual Financial Statements
and the Interim Financial Statements;

 

		(aa)	“First Milestone Amount” has the meaning set forth in Section 2.3(b);

 

		(bb)	“First Milestone Approval Date” means the date upon which the Corporation satisfies
the First Milestone Condition;

 

		(cc)	“First Milestone Condition” means the Corporation obtaining first indication
market approval for Annexin in the United States by the FDA;

 

		(dd)	“Fourth Milestone Amount” has the meaning set forth in Section 2.3(e);

 

		(ee)	“Fourth Milestone Condition” means the Corporation obtaining second indication
market approval for Annexin across Europe by the EMA;

 

		(ff)	“Fundamental Representations” has the meaning set forth in Section 5.4(b)(i);

 

		(gg)	“Governmental Authority” means any domestic or foreign government, whether federal,
provincial, state, territorial or municipal; and any governmental agency,

 

    	 	3

    	 

    

 

ministry, department,
Tribunal, commission, bureau, board or other similar instrumentality;

 

		(hh)	“IFRS” means International Financial Reporting Standards in effect at the applicable
date of determination;

 

		(ii)	“Income Tax Act” means, collectively, the Income Tax Act, R.S.C. 1985,
c. 1 (5th Supp.), the Income Tax Application Rules, R.S.C. 1985, c. 2 (5th Supp.), and the Income
Tax Regulations, C.R.C., c. 945, in each case as amended from time to time;

 

		(jj)	“Indemnitee” means any Party entitled to indemnification under Article 5 of
this Agreement;

 

		(kk)	“Indemnitor” means any Party obligated to provide indemnification under Article
5 of this Agreement;

 

		(ll)	“Indemnity Payment” has the meaning set forth in Section 5.14;

 

		(mm)	“Initial Royalty Amount” has the meaning set forth in Section 2.4(b)(i);

 

		(nn)	“Insiders” of a corporation means directors, officers, holders of more than
5% of the corporation’s shares, or employees of the corporation, or any other person not dealing at arm’s length (as
such term is defined in the Income Tax Act) with the corporation or any Affiliate or associate (as such terms is defined in the
Canada Business Corporations Act) of any of the foregoing;

 

		(oo)	“Intellectual Property” means any and all of the following and all proprietary,
intellectual property and other rights in, arising out of or associated with:

 

(i)          all
patents and utility models and applications therefor (including without limitation provisionals) and all equivalent or similar
rights anywhere in the world in inventions and discoveries including without limitation, invention disclosures;

 

(ii)         all
registered and unregistered trade-marks, service marks, trade names, trade dress, logos, business, corporate and product names
and slogans and registrations and applications for registration thereof (including intent-to-use applications);

 

(iii)        all
copyrights in copyrightable works, and all other rights of authorship, worldwide, and all applications, registrations and renewals
in connection therewith;

 

(iv)        all
maskworks, maskwork registrations and applications therefor, and any equivalent or similar rights in semiconductor masks, layouts,
architectures or topologies;

 

(v)         all
design patents, design registrations, pending patent and design applications and rights to file applications for the designs,

 

    	 	4

    	 

    

 

including all rights
of priority and rights in continuations, continuations-in-part, divisions, reexaminations, reissues and other derivative applications
and patents; and

 

(vi)        all
Internet or World Wide Web addresses, domain names and sites and applications and registrations therefor;

 

		(pp)	“Interim Financial Statements” means the unaudited interim financial statements
of the Corporation as, at and for the period ending September 30, 2014; provided that if Closing has not occurred by January 15,
2015, the Interim Financial Statements will be prepared as, at and for the period ending December 31, 2014, a copy of which
are attached hereto as Schedule “B”;

 

		(qq)	“Interim Financial Statement Date” means the date of the Interim Financial Statements;

 

		(rr)	“Investment Date” means February 12, 2010, being the effective date of a purchase
agreement by and among the Corporation, the Seller, the Parent and other parties;

 

		(ss)	“Loss” means any loss, liability, damage, cost, expense, charge, fine, penalty
or assessment, resulting from or arising out of any Claim, including the costs and expenses of any legal proceeding, assessment,
judgment, settlement or compromise relating thereto and all interest, punitive damages, fines and penalties and reasonable legal
fees and expenses incurred in connection therewith;

 

		(tt)	“Material Adverse Change” in relation to the Corporation means a change in the
business, operations, capital, properties, assets, prospects or condition, financial or otherwise, of the Corporation that materially
and adversely affects or could reasonably be expected to have a material and adverse effect on the Corporation, the Business or
the value of the securities of the Corporation;

 

		(uu)	“Milestone Amounts” means collectively, the First Milestone Amount, the Second
Milestone Amount, the Third Milestone Amount and the Fourth Milestone Amount;

 

		(vv)	“Notice Period” has the meaning set forth in Section 5.8;

 

		(ww)	“Parties” means the Purchaser and the Seller collectively, and “Party”
means any one of them;

 

		(xx)	“Purchase Price” has the meaning set forth in Section 2.2;

 

		(yy)	“Purchased Shares” has the meaning set forth in the recitals;

 

		(zz)	“Purchaser” has the meaning set forth in the preamble;

 

		(aaa)	“Purchaser Group” means the Purchaser and its Affiliates;

 

    	 	5

    	 

    

 

		(bbb)	“Royalty Amount” has the meaning set forth in Section 2.4;

 

		(ccc)	“Royalty Period End Date” means the tenth (10th) anniversary of the
later of the First Milestone Approval Date and the Second Milestone Approval Date;

 

		(ddd)	“Royalty Report” has the meaning set forth in Section 2.4(c);

 

		(eee)	“Second Milestone Amount” has the meaning set forth in Section 2.3(c);

 

		(fff)	“Second Milestone Approval Date” means the date upon which the Corporation satisfies
the Second Milestone Condition;

 

		(ggg)	“Second Milestone Condition” means the Corporation obtaining first indication
market approval for Annexin across Europe by the EMA;

 

		(hhh)	“Seller” has the meaning set forth in the preamble;

 

		(iii)	“Shareholders Agreement” has the meaning set forth in Section 6.2(f);

 

		(jjj)	“Stanford Agreement” means the License Agreement effective June 1, 2008 between
the Board of Trustees of the Leland Stanford Junior University and the Corporation, as amended by Amendment No. 1 effective as
of December 17, 2009, as further amended by Amendment No. 2 effective as of August 17, 2010 and as further amended by Amendment
No. 3 effective as of November 20, 2013 between the same parties;

 

		(kkk)	“Subsequent Royalty Amount” has the meaning set forth in Section 2.4(b)(ii);

 

		(lll)	“Tax Legislation” means collectively, the Income Tax Act, the United States
Internal Revenue Code of 1986, as amended, and all federal, provincial, state, municipal, county, territorial or other tax
statutes including all treaties, conventions, case law, interpretation bulletins, circulars and releases, rules, regulations, orders
and decrees of any jurisdiction;

 

		(mmm)	“Tax Returns” means all reports, elections, returns and other documents required
to be filed under the provisions of any applicable Tax Legislation and any tax forms required to be filed, whether in connection
with a tax return or not, under any provisions of any applicable Tax Legislation;

 

		(nnn)	“Tax” or “Taxes” means all taxes, assessments, charges, dues,
duties, rates, fees, imposts, levies and similar charges of any kind lawfully levied, assessed or imposed by any Governmental Authority
under any applicable Tax Legislation, including, Canadian federal, provincial, territorial, municipal and local, foreign or other
income, capital, goods and services, sales, use, consumption, excise, value-added, business, real property, personal property,
transfer, franchise, withholding, payroll, or employer health taxes, customs, import, anti-dumping or countervailing duties, Canada
Pension Plan contributions, provincial pension plan contributions, employment insurance premiums, and provincial workers’
compensation payments, including any interest, penalties and fines associated therewith;

 

    	 	6

    	 

    

 

		(ooo)	“Third Milestone Amount” has the meaning set forth in Section 2.3(d);

 

		(ppp)	“Third Milestone Condition” means the Corporation obtaining second indication
market approval for Annexin in the United States by the FDA;

 

		(qqq)	“Third Party Claim” has the meaning set forth in Section 5.6;

 

		(rrr)	“Tribunal” means any court (including a court of equity), arbitrator or arbitration
panel and any other Governmental Authority, stock exchange, professional or business organization or association or other body
exercising adjudicative, regulatory, judicial or quasi-judicial powers.

 

		1.2	Headings, etc.

 

The division of this Agreement
into Articles, Sections, subsections, paragraphs, subparagraphs and clauses and the insertion of headings are for the convenience
of reference only and shall not affect the construction or interpretation of this Agreement. The terms “this Agreement”,
“hereof”, “hereunder” and similar expressions refer to this Agreement and not to any particular Article,
Section, subsection, paragraph, subparagraph, clause or other portion hereof and include any agreement or instrument supplemental
or ancillary hereto.

 

		1.3	Number, etc.

 

Words importing the singular
number only shall include the plural and vice versa, and words importing the masculine gender shall include the feminine and neutral
genders and vice versa.

 

		1.4	Currency

 

Unless otherwise indicated
all dollar amounts referred to in this Agreement, including the symbol “CHF”, refer to Swiss Francs.

 

		1.5	Accounting Principles

 

Wherever
in this Agreement reference is made to “generally accepted accounting principles” or “GAAP”, such reference
shall be to the generally accepted accounting principles in effect in Canada at the date of determination as recommended
in Part II – Accounting Standards for Private Enterprises of the Handbook of Chartered Professional Accountants of Canada
and consistently applied.

 

		1.6	Additional Rules of Interpretation

 

		(a)	Persons - Unless the context otherwise requires, references in this Agreement to a “person”
are to be broadly interpreted and shall include an individual (whether acting as an executor, administrator, legal representative
or otherwise), body corporate, unlimited liability company, partnership, limited liability partnership, joint venture, trust, unincorporated
association, unincorporated syndicate, any Governmental Authority and any other legal or business entity.

 

		(b)	Trade Meanings - Unless otherwise defined herein, words or abbreviations that have well-known
trade meanings are used herein with those meanings.

 

    	 	7

    	 

    

 

		1.7	Knowledge

 

Where any representation,
warranty or other statement in this Agreement is expressed to be made by a Party to its knowledge or is otherwise expressed to
be limited in scope to matters known to such Party or of which such Party is aware, it shall mean such knowledge as is actually
known to the officers or employees of such Party who have overall responsibility for or knowledge of the matters relevant to such
statement, and such Party hereby confirms that it has made reasonable inquiries of such officers and employees.

 

		1.8	Schedules

 

The following are the Schedules
annexed hereto and incorporated in this Agreement by reference and deemed to be part hereof:

 

	Schedule “A”	-	Annual Financial Statements
	Schedule “B”	-	Interim Financial Statements
	Schedule “C”	-	Disclosure Schedule

 

		1.9	Taxes

 

Subject to any taxes required
to be withheld by the Purchaser, in accordance with applicable laws, from the Purchase Price Payments to be made hereunder, the
Purchaser shall not deduct any non-Canadian taxes from the Purchase Price payments hereunder due to the Seller.

 

Article 2

PURCHASE AND SALE

 

		2.1	Agreement of Purchase and Sale

 

Subject to the terms and
conditions of this Agreement, at the Closing Time the Seller shall sell to the Purchaser, and the Purchaser shall purchase from
the Seller, all of the Purchased Shares.

 

		2.2	Purchase Price

 

The aggregate consideration
to be paid for the Purchased Shares (the “Purchase Price”) shall be an amount equal to (i) the Closing Date
Payment, plus (ii) the aggregate of all Anniversary Payments (if any) made pursuant to Section 2.5, plus (iii) the
Milestone Amounts (if any), plus (iv) the Initial Royalty Amount (if any), plus (v) the Subsequent Royalty Amount
(if any).

 

		2.3	Payment of Purchase Price

 

The Purchaser shall pay and
satisfy the Purchase Price as follows:

 

		(a)	at the Closing Time, the Purchaser shall pay to the Seller the Closing Date Payment;

 

		(b)	within ten (10) Business Days of the satisfaction of the First Milestone Condition by the Corporation,
the Purchaser shall pay to the Seller, by wire transfer of immediately available funds to an account designated in writing by the
Seller at least two (2) Business Days prior to such payment, an amount equal to CHF

 

    	 	8

    	 

    

 

387,303 less
the aggregate of the Closing Date Payment and any Anniversary Payments previously paid by the Purchaser to the Seller and not previously
deducted from the payment of the Second Milestone Amount (the “First Milestone Amount”);

 

		(c)	within ten (10) Business Days of the satisfaction of the Second Milestone Condition by the
Corporation, the Purchaser shall pay to the Seller, by wire transfer of immediately available funds to an account designated in
writing by the Seller at least two (2) Business Days prior to such payment, an amount equal to CHF 387,303 less the aggregate
of the Closing Date Payment and any Anniversary Payments previously paid by the Purchaser to the Seller and not previously deducted
from the payment of the First Milestone Amount (the “Second Milestone Amount”);

 

		(d)	within ten (10) Business Days of the satisfaction of the Third Milestone Condition by the Corporation,
the Purchaser shall pay to the Seller, by wire transfer of immediately available funds to an account designated in writing by the
Seller at least two (2) Business Days prior to such payment, an amount equal to CHF 592,345 less the aggregate of the Closing
Date Payment and any Anniversary Payments previously paid by the Purchaser to the Seller and not previously deducted from the payment
of the First Milestone Amount and/or the Second Milestone Amount and/or the Fourth Milestone Amount (the “Third Milestone
Amount”);

 

		(e)	within ten (10) Business Days of the satisfaction of the Fourth Milestone Condition by the Corporation,
the Purchaser shall pay to the Seller, by wire transfer of immediately available funds to an account designated in writing by the
Seller at least two (2) Business Days prior to such payment, an amount equal to CHF 592,345 less the aggregate of the Closing
Date Payment and any Anniversary Payments previously paid by the Purchaser to the Seller and not previously deducted from the payment
of the First Milestone Amount, the Second Milestone Amount and/or the Third Milestone Amount (the “Fourth Milestone Amount”);

 

		(f)	the Purchaser shall pay to the Seller, in accordance with Section 2.4, the Initial Royalty Amount,
if any, less the aggregate of any Anniversary Payments previously paid by the Purchaser to the Seller and not deducted from the
payment of the Milestone Amounts; and

 

		(g)	the Purchaser shall pay to the Seller, in accordance with Section 2.4, the Subsequent Royalty Amount,
if any, less the aggregate of any Anniversary Payments previously paid by the Purchaser to the Seller and not deducted from the
payment of the Milestone Amounts.

 

		2.4	Determination and Payment of Royalty Amounts

 

The Purchaser shall make
payment to the Seller in an aggregate amount (the “Royalty Amount”), calculated, if any, as follows:

 

    	 	9

    	 

    

 

		(a)	Following the Approval Date, the Purchaser shall determine the amount, if any, of the Royalty Amount,
based on the cumulative Annexin Sales as follows:

 

		(i)	the Purchaser shall pay a royalty to the Seller on all Annexin Sales in the United States of America
from the First Milestone Approval Date until the tenth (10th) anniversary of the First Milestone Approval Date;

 

		(ii)	the Purchaser shall pay a royalty to the Seller on all Annexin Sales in Europe from the Second
Milestone Date until the tenth (10th) anniversary of the Second Milestone Approval Date; and

 

		(iii)	the Purchaser shall pay a royalty to the Seller on all Annexin Sales worldwide (excluding the United
States and the European Union) from the Approval Date to the tenth (10th) anniversary of the Approval Date.

 

		(b)	The Royalty Amount shall be equal to:

 

		(i)	an amount equal to [*]% of the first cumulative CHF 91.13 million of Annexin Sales, determined
in accordance with Section 2.3(a), following the Approval Date, to a maximum of CHF [*] (the “Initial Royalty Amount”);
plus

 

		(ii)	an amount equal to [*]% of all Annexin Sales, determined in accordance with Section 2.3(a), in
excess of CHF 91.13 million in aggregate, if any, until the Royalty Period End Date (the “Subsequent Royalty Amount”).

 

		(c)	Within ninety (90) days of the end of each fiscal year of the Corporation, commencing with the
fiscal year in which the Approval Date occurs and ending with the fiscal year in which the Royalty Period End Date occurs (the
“Final Fiscal Year”), the Purchaser shall provide the Seller with a report setting forth the number, description
and aggregate Annexin Sales during the most recently completed fiscal year of the Corporation, or in the case of the Final Fiscal
Year the Annexin Sales from January 1 of the Final Fiscal Year to the Royalty Period End Date (in each case a “Royalty
Report”) for purposes of establishing any amounts to be paid in accordance with this Section 2.4, together with an amount
equal to the Purchaser’s determination of the amount of the Royalty Amount to be paid for the particular fiscal year (the
“Annual Royalty Amount”). The Purchaser shall cause the Corporation and any other member of the Purchaser Group
to maintain its records relating to its determination of an Annual Royalty Amount for a period of three years from the date of
the applicable Royalty Report.

 

		(d)	In the event the Seller objects to the Annual Royalty Amount, the Seller shall deliver written
notice of such objection to Purchaser within thirty (30) days of the Seller’s receipt of a Royalty Report. If the Seller
does not notify the Purchaser of any dispute within such thirty (30) day period, the Annual Royalty Amount set forth in the Royalty
Report shall be deemed to binding on the Parties. The Seller and the Purchaser shall attempt in good faith to resolve any such
dispute as promptly as practicable. If the Seller and Purchaser are unable to resolve any dispute regarding the calculation of
the Annual Royalty Amount

 

    	 	10

    	 

    

 

within ten (10)
days (or such longer period as the Purchaser and the Seller shall mutually agree in writing) of the Seller’s notice of a
dispute, the Parties shall engage a mutually agreeable nationally-recognized accounting firm (the “Accounting Firm”)
to resolve all issues having a bearing on such dispute and such resolution shall be final and binding on the Parties. The Accounting
Firm shall deliver a statement setting forth its own calculation of the Annual Royalty Amount (determined in accordance with this
Agreement) to the Parties within thirty (30) days of the submission of the matter to such firm. The fees and expenses of the
Accounting Firm in resolving such dispute shall be borne by the Seller, unless the Accounting Firm determination of the Annual
Royalty Amount is greater than 105% of the Purchaser’s determination of the Annual Royalty Amount, in which case the fees
and expenses of the Accounting Firm shall be borne by the Purchaser.

 

		(e)	Within ten (10) Business Days after the final determination of an Annual Royalty Amount in
accordance with Section 2.4(d) the Purchaser shall pay to the Seller the excess of the Annual Royalty Amount as finally determined
over the payment made in Section 2.4(c), if any, or the Seller shall pay to the Purchaser the excess of the payment made in Section
2.4(c) over the Annual Royalty Amount as finally determined, if any, as the case may be, by wire transfer of immediately available
funds to an account designated in writing by the payee at least two (2) Business Days prior to such payment.

 

		2.5	Anniversary Payments

 

On each anniversary of the
Closing Date and prior to the Approval Date, the Purchaser shall pay the Seller an amount equal to CHF 318,955 (each such payment
being an “Anniversary Payment”).

 

		2.6	Manner of Payments

 

All payments required to
be made by the Purchaser to or to the order of the Seller under this Article 2 shall be made in Swiss Francs.

 

		2.7	Termination

 

If the Purchaser Group abandons
the development and marketing of Annexin and provides written evidence of such abandonment, this Agreement may be terminated at
any time thereafter, in the sole and absolute discretion of the Purchaser, by providing thirty (30) days’ prior written
notice to the Seller. In the event that the Purchaser exercises its right to terminate this Agreement the Parties will be discharged
from any further obligations under this Agreement except that:

 

		(a)	all Purchase Price payments due to the date of termination shall become immediately due and payable
by the Purchaser to the Seller; provided that if the Approval Date has not yet occurred when this Agreement is terminated the Purchaser
shall not be required to pay a pro rata amount of the upcoming Anniversary Payment;

 

    	 	11

    	 

    

 

		(b)	the Purchaser shall cause the Corporation to use its commercially reasonable efforts to assign
all of its rights and obligations under the Stanford Agreement to the Seller;

 

		(c)	the Purchaser shall cause the Corporation to deliver all materials, regulatory documents, protocols
and any other property of the Corporation pertaining to the development of Annexin to the Seller and all Intellectual Property
of the Corporation or the Purchaser Group pertaining to Annexin; and

 

		(d)	each Party’s respective obligations under Section 7.2 and Section 7.3 will continue indefinitely.

 

Article 3

REPRESENTATIONS AND WARRANTIES OF THE SELLER AND RELATING TO THE CORPORATION 

 

		3.1	Seller’s Representations and Warranties

 

The Seller represents and
warrants to the Purchaser as follows, and acknowledges that the Purchaser is relying on such representations and warranties in
connection with the transactions contemplated herein, including, without limitation, the purchase of the Purchased Shares:

 

		(a)	Incorporation of the Seller.

 

The Seller is duly incorporated,
organized and subsisting under the laws of Canada . No proceedings have been taken or authorized by the Seller or by any other
person with respect to the bankruptcy, insolvency, liquidation, dissolution or winding up of the Seller or with respect to any
amalgamation, merger, consolidation, arrangement or reorganization of, or relating to, the Seller nor, to the knowledge of the
Seller, have any such proceedings been threatened by any other person.

 

		(b)	Authorization of Transaction by Seller.

 

The Seller has the corporate
power, authority and capacity to execute and deliver this Agreement, to hold the Purchased Shares and to perform its other obligations
hereunder. The execution and delivery of this Agreement and the completion of the transactions herein contemplated have been duly
and validly authorized by all necessary action on behalf of the Seller and this Agreement has been duly and validly executed and
delivered by the Seller and is a valid and binding obligation of the Seller enforceable against the Seller in accordance with its
terms. There is no litigation, action, suit, investigation, hearing, claim, complaint, grievance, arbitration proceeding or other
proceeding, including any appeal or review and any application for same, in progress, pending, or, to the knowledge of the Seller,
threatened against or affecting the Seller or affecting the title of the Seller to any of the Purchased Shares at law or in equity
or before or by any Tribunal and, to the knowledge of the Seller, there are no grounds on which any such legal proceeding might
be commenced with any reasonable likelihood of success nor is there any order outstanding against or affecting the Seller which,
in any such case, affects adversely or might affect adversely the ability of the Seller to enter into this Agreement or to perform
its obligations hereunder. Seller has obtained all authorizations, consents or approvals required to be obtained or performed by
the Seller in order to complete the transactions contemplated by this Agreement.

 

    	 	12

    	 

    

 

		(c)	Title to Purchased Shares.

 

The Seller is the registered
and beneficial owner of the Purchased Shares to be sold by the Seller to the Purchaser hereunder. The Seller has good and marketable
title to such Purchased Shares, free and clear of all Encumbrances. No person has, or has any right capable of becoming, any agreement,
option, understanding or commitment for the purchase or other acquisition from the Seller of any of the Purchased Shares.

 

		(d)	Residence of Seller.

 

The Seller is not a “non-resident”
of Canada within the meaning of the Income Tax Act.

 

		(e)	No Finders’ Fee.

 

No broker, finder, agent
or similar intermediary has acted on behalf of the Seller in connection with this Agreement or the transactions contemplated hereby,
and there is no brokerage commission, finders’ fee or similar fee payable by the Corporation or the Purchaser in connection
therewith.

 

		3.2	Representations and Warranties relating to the Corporation

 

The Seller represents and
warrants to the Purchaser and acknowledges that the Purchaser is relying on such representations and warranties in connection with
the transactions contemplated herein, including, without limitation, the purchase of the Purchased Shares:

 

		(a)	Incorporation and Organization of the Corporation. 

 

The
Corporation is a corporation duly incorporated, organized and validly subsisting under the laws of Canada, and is in good standing
under the laws of such jurisdiction.

 

		(b)	Qualification.

 

To the Seller’s knowledge,
the Corporation is duly qualified or licensed to carry on business in every jurisdiction in which the nature of the Business or
the property owned or leased by the Corporation makes such qualification or license necessary, except where the failure to be so
in any such case or taken together would not have a material adverse effect on the Corporation.

 

(c)          Shareholder
Agreements. Other than as set forth in the Shareholders Agreement and the articles of the Corporation, as amended, the Seller
is not a party to any Contract that relates to or affects the management of the Corporation or restricts the ability of the Corporation
to issue securities or the ability of shareholders of the Corporation to freely transfer or alienate any outstanding securities
of the Corporation or securities of the Corporation that may hereafter be issued, or that creates a voting trust, voting agreement,
pooling agreement, drag-along, right of first refusal, pre-emptive right or proxy with respect to any of the outstanding securities
of the Corporation or securities of the Corporation that hereafter may be issued.

 

		(d)	Conflicting Instruments.

 

To the knowledge of the Seller,
the consummation of the transactions contemplated herein will not conflict with, or result in the violation of, or a default under,
any applicable law, rule or

 

    	 	13

    	 

    

 

regulation, any of the terms
and provisions of the articles or by-laws of the Corporation or of any Contract to which the Corporation is a party or by which
it is bound, or cause the rights of any party (including any right to the vesting of purchase rights with respect to any outstanding
securities or securities which hereafter may be issued) to any such Contract to accelerate according to the terms of such Contract.

 

		(e)	Subsidiaries and Other Interests.

 

To the knowledge of the Seller,
the Corporation has no subsidiaries, is not and has not been a partner in a partnership, is not and has not participated in any
joint venture, and does not own, and has not agreed or become bound to acquire any securities issued by, or acquire any equity
or ownership interest in, any other business or person. To the knowledge of the Seller, the Corporation is not subject to any obligation
or requirement to provide funds to or to make any investment in any business or person by way of loan, capital contribution or
otherwise.

 

		(f)	Minute Books.

 

To the knowledge of the Seller,
the minute books of the Corporation have been made available to the Purchaser or counsel to the Purchaser and contain all articles,
by-laws and resolutions and a complete and accurate record of all meetings and actions of directors (and committees thereof) and
shareholders of the Corporation since the Investment Date, and reflect all transactions referred to in such proceedings accurately
up until the Closing Time. The share ledgers and registers of the Corporation are complete and reflect all issuances, transfers,
repurchases and cancellations of shares in the capital of the Corporation.

 

		(g)	Financial Statements.

 

The
Financial Statements have been prepared in accordance with generally accepted accounting principles applied on a basis consistent
with prior periods and completely and accurately presents the financial position of the Corporation as at December 31, 2013 in
respect of the Annual Financial Statements and as at the Interim Financial Statement Date in respect of the Interim Financial
Statements, including, without limiting the generality of the foregoing, all liabilities of the Corporation of every nature and
kind whether contingent, deferred or otherwise, including but not limited to all liabilities or provision for Taxes of any and
every kind due or to become due as at such date. The Financial Statements are in all respects in accordance with the books and
records of the Corporation. The books and records of the Corporation completely and accurately record all financial transactions
of the Corporation in accordance with sound business and financial practice. There has not been, since December 31, 2013, any:

 

		(i)	payment or satisfaction of any obligation or liability, absolute or contingent, other than current
liabilities or obligations disclosed in the Financial Statements and current liabilities or obligations incurred since the Interim
Financial Statement Date in the ordinary course of the business of the Corporation or in connection with the transactions contemplated
by this Agreement;

 

		(ii)	declaration, setting aside or payment of any dividend, redemption or repurchase of any outstanding
shares, or any distribution by the Corporation of its properties or assets to its shareholders, other than salaries paid in the
ordinary course;

 

    	 	14

    	 

    

 

		(iii)	material loss, destruction or damage to any property of the Corporation, whether or not insured;

 

		(iv)	material change in any of the Corporation’s personnel or their terms and conditions of employment;

 

		(v)	waiver of any valuable right, claim or debt owed to the Corporation;

 

		(vi)	acquisition or disposition of any material asset (or any Contract or arrangement therefor) in excess
of $100,000, or any other material transaction by the Corporation;

 

		(vii)	authorization, agreement or commitment to do any of the foregoing; or

 

		(viii)	to the knowledge of the Seller, Material Adverse Change.

 

		(h)	Business in the Ordinary Course.

 

To the knowledge of the Seller,
the Corporation has not carried on any business other than the Business since the Investment Date. To the knowledge of the Seller,
the operations and Business of the Corporation between the Investment Date and the date hereof have been carried
on in the ordinary course and, except as set forth in the Financial Statements, the Corporation has not incurred any obligation
or liability out of the ordinary course.

 

		(i)	Compliance With Laws.

 

To the knowledge of the Seller,
the Corporation is conducting the Business in compliance in all material respects with all applicable laws, rules and regulations
of each jurisdiction in which the Business is carried on, and is not in breach in any material respect of any such laws, rules
or regulations except where the failure to be so in any such case or taken together would not have a material adverse effect on
the Corporation.

 

		(j)	Tax Matters.

 

The
Corporation has duly filed all Tax Returns required to be filed by it. All such Tax Returns, and all materials accompanying such
Tax Returns, are true, correct and complete in all material respects and contain accurate disclosure. The Corporation has paid
all Taxes which are due and payable by it on or prior to the date hereof, and all governmental or municipal charges or levies,
penalties, interest and fines in respect of such Taxes due and payable by it on or prior to the date hereof; to the extent required,
adequate provisions have been made for all such Taxes, charges, levies, penalties, interest and fines payable for the current year
for which Tax Returns are not yet filed; there is no action, suit, proceeding, investigation or claim pending or, to the knowledge
of the Corporation, threatened, against the Corporation in respect of Taxes, governmental or municipal charges, levies or assessment,
nor are there any matters under discussion with any governmental or municipal authority relating to Taxes, governmental or municipal
charges, levies or assessment asserted by any such authority. The Corporation has withheld from each payment made to any of its
officers, directors, employees, shareholders, creditors or other persons, all amounts which it is required by law to withhold or
deduct and has duly remitted all amounts so withheld or deducted to the proper recipients thereof within the time periods and in
the manner required by such laws.

 

    	 	15

    	 

    

 

		(k)	Property & Assets.

 

The Corporation has good
and marketable title, or valid leasehold title pursuant to the leases described in Schedule 3.2(k) of the Disclosure Schedule,
to all of its properties and assets, free and clear of all Encumbrances. All machinery and equipment included in such properties
and assets is in good condition and repair except for reasonable wear and tear, and all leases of real or personal property to
which the Corporation is a Party are fully effective and afford the Corporation peaceful and undisturbed possession of the subject
matter of the lease. To the knowledge of the Seller, the Corporation is not in violation of any zoning, building or safety ordinance,
regulation or requirement or other law or regulation applicable to the operation of owned or leased properties that is likely to
impede the normal operation of the Business. The Corporation does not own any real property.

 

		(l)	Liabilities and Debt Instruments.

 

Except
as set forth in the Financial Statements or as may exist between the Corporation and members of the Purchaser Group, the Corporation
does not have any liabilities, obligations or commitments (including, without limitation, indebtedness, Tax liabilities, guarantees,
indemnifications, surety or similar obligations), whether accrued, absolute, contingent or otherwise. To the knowledge of
the Seller, the Corporation is not a party to or bound by or subject to: (i) any bond, debenture, promissory note, credit facility
or other Contract evidencing indebtedness for borrowed money; or (ii) any agreement, Contract to create, assume or issue any of
the foregoing. To the knowledge of the Seller, the Corporation is not in default under any obligation (contingent or otherwise)
in respect of borrowed money or pursuant to any Contract referred to above, and none of the Corporation’s debts or liabilities
is guaranteed by any other person.

 

		(m)	Employee Benefits.

 

The Corporation does not
maintain any Benefit Plans.

 

		(n)	Environmental, Health and Safety Matters.

 

To the knowledge of the Seller,
the operations of the Corporation (as well as any property or assets of the Corporation whether or not used in carrying on of the
Business) are not in, and have not been in, violation of any applicable laws, regulations, permits, licences, approvals, policies,
guidelines or orders of any governmental or municipal authority relating to environmental, health or safety matters, including
the release of hazardous substances.

 

		(o)	Litigation.

 

To the knowledge of the Seller,
there is no claim, action, law suit, proceeding, complaint, charge or investigation pending or threatened against the Corporation.
The foregoing includes, without limitation, actions pending or, to the knowledge of the Seller, threatened, involving the prior
employment or engagement, as applicable, of any of the employees or independent contractors of the Corporation, their use in connection
with the Business of the Corporation of any information, creations or techniques allegedly proprietary to any of their former employers
or other persons, or their obligations under any Contracts with prior employers or other persons. Neither the Corporation nor any
of its employees, independent contractors, officers or directors, is a party to, or subject to the provisions of, any order, writs,
injunction, judgment or decree of any court or governmental agency or instrumentality relating to the Corporation or the Business.
The Corporation is not and has not been since the Investment Date engaged in any dispute with any present or former

 

    	 	16

    	 

    

 

officers, directors, employees,
independent contractors or shareholders. There is no action, suit or proceeding by the Corporation currently pending or, to the
knowledge of the Seller, which the Corporation presently intends to initiate.

 

		(p)	Stanford Agreement.

 

The Stanford Agreement: (i)
is valid and binding upon the Corporation and, to the knowledge of the Seller, the other parties thereto; (ii) is in full force
and effect; and (iii) has not been breached by the Corporation or, to the knowledge of the Seller, any other party thereto, nor
is there any event or condition which, with the passage of time would constitute a material default or a material breach by the
Corporation or any third party. No party to the Stanford Agreement has indicated to the Corporation, nor does the Seller have any
reasonable basis to believe that any party to the Stanford Agreement shall indicate, that it intends to cancel, withdraw, modify
or amend any of same. There is no consent or approval required from any party to the Stanford Agreement in order to complete the
transactions contemplated by this Agreement. A true and complete copy of the Stanford Agreement has been delivered to the Purchaser
or counsel for the Purchaser.

 

		(q)	Insiders.

 

Except as set forth in Schedule
3.2(q) of the Disclosure Schedule, there are no Contracts between the Corporation and any of the Seller’s Insiders (other
than Contracts of employment and share subscription agreements entered into in the ordinary course). Except for usual compensation
paid in the ordinary course of business, consistent with past practice, the Corporation has not made any payment or loan to, or
borrowed any monies from or is otherwise indebted to, any of the Seller’s Insiders.

 

		(r)	Employees.

 

		(i)	The Corporation has no employees and only 1 independent contractor, who is Bill Dickie. The agreement
governing the terms of the independent contractor’s services has been provided to the Purchaser. There has not been and there
is not currently any material disagreement or other difficulties with any of the Corporation’s present or former employees
or independent contractors. To the knowledge of the Seller, no officer or key employee of the Corporation has any present intention
of terminating his or her services to the Corporation nor to the knowledge of the Seller does the Corporation have any present
intention of terminating the service of any such person in each case, other than as contemplated herein.

 

		(ii)	To the knowledge of the Seller, since the Investment Date no present or former employee or independent
contractor of the Corporation is a party to or has violated any term of any employment contract, consulting agreement, non-competition
or non-solicitation agreement, patent or other proprietary information agreement or similar Contract with, or any fiduciary duty
in favour of, a former employer of such employee or independent contractor or any other third party. The Corporation has not received
any notice from any third party alleging that such a violation has occurred. To the knowledge of the Seller, the

 

    	 	17

    	 

    

 

continued employment
or engagement by the Corporation of its present employees or contractors shall not result in any such violation.

 

		(iii)	Since the Investment Date, there have been no claims of wrongful dismissal, or complaints, inquiries
or claims made against the Corporation resulting from the violation or alleged violation of any applicable employment law or regulation,
including any employment equity, human rights, health or safety law or regulation, or any agreement or arrangement with respect
to Benefit Plans.

 

		(iv)	Since the Investment Date, the Corporation has complied with all applicable federal, provincial,
state and any other applicable laws and regulations respecting employment and employment practices, terms and conditions of employment,
wages and hours and other laws related to employment, and there are no arrears in the payments of wages, withholding Taxes, Canada
Pension Plan premiums, employment insurance premiums or other similar obligations.

 

		(v)	The Corporation is not a party to any collective bargaining agreement and, to the Corporation’s
knowledge, no organizational efforts to establish a collective bargaining or similar arrangement are presently being made with
respect to any of its employees.

 

		(vi)	The Corporation is not a party to and is not bound by any Contract for the: (A) employment of any
employee that cannot be terminated without cause on provisions of notice limited to the minimum notice requirements under the Employment
Standards Act, 2000 (Ontario), as amended; or (B) engagement of any independent contractor or consultant that cannot be terminated
on less than sixty (60) days’ notice.

 

		(s)	Material Information.

 

No representation or warranty
by the Seller contained in this Agreement contains any untrue statement of a material fact or omits to state a material fact necessary
to make the statements therein, in light of the circumstances in which they were made, not false or misleading.

 

		3.3	Non-Waiver

 

The Purchaser and the Purchaser
Group shall not have any recourse against the Seller in respect of facts or circumstances that are reflected in public filings
of any member of the Purchaser Group or in respect of facts or circumstances of which any member of the Purchaser Group other than
the Corporation had knowledge.

 

    	 	18

    	 

    

 

Article 4

PURCHASER’S REPRESENTATIONS AND WARRANTIES

 

		4.1	Purchaser’s Representations and Warranties

 

The Purchaser represents
and warrants to the Seller as follows and acknowledges that the Seller is relying on such representations and warranties in connection
with the transactions contemplated herein:

 

		(a)	Incorporation of the Purchaser

 

The Purchaser is duly incorporated,
organized and subsisting under the laws of its jurisdiction of incorporation and is in good standing under the laws of such jurisdiction.
No proceedings have been taken or authorized by the Purchaser or by any other person with respect to the bankruptcy, insolvency,
liquidation, dissolution or winding up of the Purchaser or with respect to any amalgamation, merger, consolidation, arrangement
or reorganization of, or relating to, the Purchaser nor, to the knowledge of the Purchaser, have any such proceedings been threatened
by any other person.

 

		(b)	Authorization.

 

The Purchaser has all the
necessary corporate or other power, authority and capacity to (i) own and operate its properties and assets; (ii) carry on its
business as presently conducted and proposed to be conducted; (iii) purchase or acquire the Purchased Shares; and (iv) execute
and deliver this Agreement and to perform all of its obligations hereunder. The execution and delivery of this Agreement, and the
consummation of the transactions herein contemplated, has been duly authorized by all necessary corporate or other action of the
Purchaser.

 

		(c)	Charter Documents and By-laws, etc.

 

The execution, delivery and
performance of this Agreement, and the consummation of the transactions herein contemplated, shall not conflict with or constitute
a default under or result in the breach of: (i) any provision of the constating documents or any resolution of the directors or
shareholders of the Purchaser (if applicable); or (ii) any statute, law or regulation of any jurisdiction as such statute, law
or regulation relates to the Purchaser.

 

		(d)	Binding Obligation.

 

Upon due execution by the
Seller and the Purchaser, this Agreement will constitute a legally valid and binding obligation of the Purchaser enforceable in
accordance with its respective terms except as limited by applicable bankruptcy, insolvency, reorganization, moratorium or other
similar laws affecting creditors’ rights generally.

 

		(e)	No Finders’ Fee.

 

The Purchaser has carried
on all negotiations relating to this Agreement and the transactions contemplated by this Agreement without intervention on its
behalf of any other party in such a manner as to give rise to any valid claim for a brokerage commission, finder’s fee or
other like payment against the Seller.

 

    	 	19

    	 

    

 

		4.2	Non-Waiver

 

No investigation made by
or on behalf of the Seller at any time shall waive, diminish the scope of or otherwise affect any representation or warranty made
by the Purchaser in this Agreement.

 

Article 5

INDEMNIFICATION

 

		5.1	Non-Merger and Exclusive Remedy

 

The representations, warranties,
covenants and other obligations contained in this Agreement and in any agreement, certificate, affidavit, statutory declaration
or other document delivered or given pursuant to this Agreement shall not merge on Closing and, notwithstanding the Closing or
any investigation made by any Party with respect thereto, shall continue in full force and effect until the dates specified in
Section 5.4 hereof. All claims by any Party after the Closing in respect of such representations and warranties (but not, for greater
certainty, any of such covenants and other obligations (which are intended to be continuing in nature)) shall be subject to the
conditions and limitations set forth in this Article 5 and the rights of indemnity in this Article 5 shall be the sole and exclusive
remedy of each Party in respect of such claims.

 

		5.2	Indemnification by Seller

 

Subject to the limitations
in Sections 5.4(a) and 5.4(b), the Seller shall indemnify, defend and save harmless the Purchaser from and against any and all
Losses suffered or incurred by the Purchaser, as a direct or indirect result of, or arising in connection with or related in any
manner whatever to:

 

		(a)	any misrepresentation or breach of warranty made or given by the Seller in this Agreement or in
any agreement, certificate, affidavit, statutory declaration or other document delivered or given pursuant to this Agreement; or

 

		(b)	any failure by the Seller to observe or perform any covenant or obligation contained in this Agreement
or in any agreement, certificate, affidavit, statutory declaration or other document delivered or given pursuant to this Agreement.

 

		5.3	Indemnification by the Purchaser

 

Subject to limitations in
Section 5.4(c), the Purchaser and Parent shall jointly and severally indemnify, defend and save harmless the Seller from and against
any and all Losses suffered or incurred by it, as a direct or indirect result of, or arising in connection with or related in any
manner whatsoever to:

 

		(a)	any misrepresentation or breach of any warranty made or given by the Purchaser in this Agreement;

 

		(b)	any misrepresentation or breach in any agreement, certificate, affidavit, statutory declaration
or other document delivered or given pursuant to this Agreement; or

 

    	 	20

    	 

    

 

		(c)	any failure by the Purchaser to observe or perform any covenant or obligation contained in this
Agreement or in any agreement, certificate, affidavit, statutory declaration or other document delivered or given pursuant to this
Agreement, including any failure to pay any portion of the Purchase Price.

 

		5.4	Time Limitations

 

		(a)	Subject to Section 5.4(b), the Seller shall have no liability to the Purchaser for any Loss arising
from any Claim relating to a breach of any representation or warranty by the Seller contained in this Agreement or in any agreement,
certificate, affidavit, statutory declaration or other document delivered or given pursuant to this Agreement unless the Purchaser
gives notice to the Seller specifying in reasonable detail the factual basis of the Claim and a reasonable estimate of the amount
thereof on or before that date which is two (2) years after the Closing Date.

 

		(b)	Despite the provisions of Section 5.4(a):

 

		(i)	notice with respect to Claims relating to Section 3.1(a) (Incorporation of the Seller.),
Section 3.1(b) (Authorization of Transaction by Seller.), Section 3.1(c) (Title to Purchased Shares.) and Section
3.1(e) (No Finders’ Fee.) (collectively, the “Fundamental Representations”) may be given at any
time after the Closing Date and prior to the 30th day following the expiration of all applicable statute of limitation
periods (including all extensions thereof);

 

		(ii)	the period to give notice with respect to Claims relating to Section 3.1(d) (Residence of Seller.)
and 3.2(j) (Tax Matters.) shall be the date which is sixty (60) days following the expiration of the period during which
an assessment, reassessment or other form of recognized document assessing liability for tax, interest or penalties under applicable
Tax Legislation in respect of any taxation year to which such representations and warranties extend could be issued (after giving
effect to any extensions or waivers thereof),

 

except in the case
of claims for fraud, in which case, such representations and warranties shall not terminate and shall survive indefinitely; provided,
any representation or warranty in respect of which indemnity may be sought under this Article 5, and the indemnity with respect
thereto, shall survive the time at which it would otherwise terminate pursuant to this Section 5.4 if notice of the inaccuracy
or breach or potential inaccuracy or breach thereof giving rise to such right or alleged right of indemnity shall have been given
to the Party against whom such indemnity may be sought prior to such time.

 

		(c)	The Purchaser and Parent shall have no liability to the Seller for any Loss arising from any Claim
relating to a breach of any representation or warranty contained in this Agreement or in any agreement, certificate, affidavit,
statutory declaration or other document delivered or given pursuant to this Agreement unless the Seller gives notice to the Purchaser
or Parent specifying in reasonable

 

    	 	21

    	 

    

 

detail the factual
basis of the Claim and a reasonable estimate of the amount thereof on or before that date which is two (2) years after the Closing
Date.

 

		(d)	The covenants of each Party in this Agreement shall survive the Closing and, notwithstanding such
Closing, shall continue in full force and effect for the benefit of the other Party in accordance with the terms hereof.

 

		5.5	Limitations on Amount 

 

		(a)	The Seller shall not have any liability under Section 5.2(a) unless and until the aggregate of
the Losses collectively, in respect of all Claims at any time asserted by the Purchaser pursuant to this Article 5, exceeds CHF
45,565, in which event the amount of all such Losses including such CHF 45,565 amount may be asserted.

 

		(b)	The Seller shall not have any liability under Section 5.2(a) for any Claim resulting solely from
any action or inaction on the part of any member of the Purchaser Group.

 

		(c)	The Purchaser shall not have any liability under Section 5.3(a) unless and until the aggregate
of the Losses in respect of all Claims at any time asserted by the Seller pursuant to this Article 5 exceeds CHF 45,565, in which
event the amount of all such Losses including such CHF 45,565 amount may be asserted.

 

		5.6	Limited Recourse

 

The aggregate liability of
the Seller under Section 5.2(a) (other than with respect to a misrepresentation involving fraud) shall be limited to the Purchase
Price paid or otherwise payable by the Purchaser to the Seller hereunder.

 

		5.7	Notice of Third Party Claims

 

If an Indemnitee receives
notice of the commencement or assertion of any Claim asserted against the Indemnitee that is paid or payable to, or claimed by,
any person who is not a Party to this Agreement (a “Third Party Claim”), the Indemnitee shall give the Indemnitor
reasonably prompt notice thereof, but in any event no later than thirty (30) days after receipt of such notice of such Third Party
Claim. Such notice to the Indemnitor shall describe the Third Party Claim in reasonable detail and shall indicate, if reasonably
practicable, the estimated amount of the Loss that has been or may be sustained by the Indemnitee.

 

		5.8	Defence of Third Party Claims

 

The Indemnitor may participate
in or assume the defence of any Third Party Claim by giving notice to that effect to the Indemnitee not later than thirty (30)
days after receiving notice of that Third Party Claim (the “Notice Period”). The Indemnitor’s right to
do so shall be subject to the rights of any insurer or other Party who has potential liability in respect of that Third Party Claim.
The Indemnitor shall pay all of its own expenses of participating in or assuming such defence. The Indemnitee shall co-operate
in good faith in the defence of each Third Party Claim, even if the defence has been assumed by the Indemnitor and may participate
in such defence assisted by counsel of its own choice at its own expense. If the Indemnitee has not received notice within the
Notice Period that the Indemnitor has

 

    	 	22

    	 

    

 

elected to assume the defence
of such Third Party Claim, the Indemnitee may, at its option, elect to settle or compromise the Third Party Claim or assume such
defence, assisted by counsel of its own choosing and the Indemnitor shall be liable for all reasonable costs and expenses paid
or incurred in connection therewith and any Loss suffered or incurred by the Indemnitee with respect to such Third Party Claim.
If the Indemnitor elects to assume the defence of a Third Party Claim under this Section 5.8 or fails to assume the defence, the
Indemnitor shall not have the right thereafter to contest its liability for such claim.

 

		5.9	Assistance for Third Party Claims

 

The Indemnitor and the Indemnitee
will use all reasonable efforts to make available to the person that is undertaking and controlling the defence of any Third Party
Claim (the “Defending Party”),

 

		(a)	those employees and other persons whose assistance, testimony or presence is necessary to assist
the Defending Party in evaluating and in defending any Third Party Claim; and

 

		(b)	all documents, records and other materials in the possession of such Party reasonably required
by the Defending Party for its use in defending any Third Party Claim,

 

and shall otherwise cooperate
with the Defending Party. The Indemnitor shall be responsible for all reasonable expenses associated with making such documents,
records and materials available and for all reasonable expenses of any employees or other persons made available by the Indemnitee
to the Indemnitor hereunder, which expense shall not exceed the actual cost to the Indemnitee associated with such employees and
other persons.

 

		5.10	Settlement of Third Party Claims

 

If an Indemnitor elects to
assume the defence of any Third Party Claim as provided in Section 5.8, the Indemnitor shall not be liable for any legal expenses
subsequently incurred by the Indemnitee in connection with the defence of such Third Party Claim following the receipt by the Indemnitee
of notice of such assumption. However, if in the opinion of the Indemnitee, acting reasonably, there is a conflict between the
interests of the Indemnifying Party and the interests of the Indemnitee with respect to such Third Party Claim, or if the Indemnitor
fails to take reasonable steps necessary to defend diligently such Third Party Claim within thirty (30) days after receiving notice
from the Indemnitee that the Indemnitee believes on reasonable grounds that the Indemnitor has failed to take such steps, the Indemnitee
may, at its option, elect to assume the defence of and to negotiate, settle or compromise the Third Party Claim assisted by counsel
of its own choosing and the Indemnitor shall also be liable for all reasonable costs and expenses paid or incurred in connection
therewith. The Indemnitor shall not, without the prior written consent of the Indemnitee, enter into any compromise or settlement
of a Third Party Claim, which would lead to liability or create any other obligation, financial or otherwise, on the Indemnitee.

 

		5.11	Direct Claims

 

Any Claim other than a Third
Party Claim (a “Direct Claim”) shall be asserted by giving the Indemnitor reasonably prompt written notice thereof,
but in any event not later than sixty (60) days after the Indemnitee becomes aware of such Direct Claim. The Indemnitee shall make
available to the

 

    	 	23

    	 

    

 

Indemnitor the information
relied upon by the Indemnitee to substantiate its right to be indemnified hereunder, together with such other information as the
Indemnitor may reasonably request. The Indemnitor shall then have a period of thirty (30) days within which to respond in writing
to such Direct Claim. If the Indemnitor does not so respond within such thirty (30) day period (or any mutually agreed upon extension
thereof), the Indemnitor shall be deemed to have rejected such Direct Claim, and in such event the Indemnitee shall be free to
pursue such remedies as may be available to the Indemnitee.

 

		5.12	Failure to Give Timely Notice

 

A failure to give timely
notice as provided in this Article 5 shall not affect the rights or obligations of any Party except and only to the extent that,
as a result of such failure, any Party which was entitled to receive such notice was deprived of its right to recover any payment
under its applicable insurance coverage or was otherwise directly and materially damaged as a result of such failure.

 

		5.13	Set-off

 

The Purchaser shall be entitled
to set-off the amount of any Loss for which indemnification is sought under Section 5.2 once finally determined in accordance with
this Article 5 as damages or by way of indemnification against any other amounts payable by the Purchaser to the Seller pursuant
to this Agreement.

 

		5.14	Reductions and Subrogation

 

If the amount of any Loss
at any time subsequent to the making of any payment on account of any Loss required to paid pursuant to this Article 5 (an “Indemnity
Payment”) in respect of that Loss is reduced by any recovery, settlement or otherwise under or pursuant to any insurance
coverage, or pursuant to any claim, recovery, settlement or payment by or against any other person, the amount of such reduction
(less any costs, expenses (including Taxes) or premiums incurred in connection therewith), shall promptly be repaid by the Indemnitee
to the Indemnitor. Upon making a full Indemnity Payment, the Indemnitor shall, to the extent of such Indemnity Payment, be subrogated
to all rights of the Indemnitee against any third party that is not an affiliate of the Indemnitee in respect of the Loss to which
the Indemnity Payment relates. Until the Indemnitee recovers full payment of its Loss, any and all claims of the Indemnitor against
any such third party on account of such Indemnity Payment shall be postponed and subordinated in right of payment to the Indemnitee’s
rights against such third party. Without limiting the generality or effect of any other provision hereof, the Indemnitee and Indemnitor
shall duly execute upon request all instruments reasonably necessary to evidence and perfect such postponement and subordination.

 

		5.15	Tax Effect

 

If any Indemnity Payment
received by an Indemnitee would constitute taxable income or be subject to a tax benefit to such Indemnitee, the Indemnitor shall
pay to the Indemnitee at the same time and on the same terms, as to interest and otherwise, as the Indemnity Payment an additional
or lesser amount, as the case may be, to place the Indemnitee in the same after-tax position as it would have been if the Indemnity
Payment had been received without the tax deduction or benefit.

 

		5.16	Additional Rules and Procedures

 

The Indemnitee and the Indemnitor
shall co-operate fully with each other with respect to Third Party Claims, shall keep each other fully advised with respect thereto
(including supplying

 

    	 	24

    	 

    

 

copies of all relevant documentation
promptly as it becomes available) and shall each designate a senior officer who shall keep himself informed about and be prepared
to discuss the Third Party Claim with his counterpart and with counsel at all reasonable times.

 

Article 6

CLOSING ARRANGEMENTS

 

		6.1	Date, Place and Time of Closing

 

The Closing shall take place
at the offices of Dentons Canada LLP, located at Suite 1420, 99 Bank Street, Ottawa, Ontario K1P 1H4 at the Closing Time on the
Closing Date, or at such other place, on such other date and at such other time as may be agreed upon in writing by the Parties.

 

		6.2	Closing Deliveries of the Seller

 

At the Closing Time, the
Seller shall deliver or cause to be delivered to the Purchaser, the following:

 

		(a)	a transfer by the Seller to the Purchaser (or as the Purchaser may otherwise direct) of the Purchased
Shares, or certificates representing the Purchased Shares duly endorsed for transfer to the Purchaser (or as the Purchaser may
otherwise direct);

 

		(b)	all documentation and other evidence reasonably requested by the Purchaser in order to establish
the due authorization and completion of the transactions contemplated by this Agreement, including the taking of all corporate
proceedings by the boards of directors and shareholders of the Seller and the Corporation required to effectively carry out the
obligations of the Seller pursuant to this Agreement;

 

		(c)	duly executed resignation effective as at the Closing Time of each resigning Seller nominee director
of the Corporation;

 

		(d)	releases from the Seller and Bill Dickie of all Claims they may have against the Corporation as
at the Closing Time in a form acceptable to the Seller, acting reasonably;

 

		(e)	a consulting agreement between the Corporation and WJD Associates Inc., in form and substance satisfactory
to the Purchaser signed by Bill Dickie on behalf of WJD Associates Inc.;

 

		(f)	written consent of the Seller to the termination of that certain Unanimous Shareholders Agreement
made as of December 6, 2010, as amended (the “Shareholders Agreement”).

 

    	 	25

    	 

    

 

		6.3	Closing Deliveries of the Purchaser

 

At the Closing Time, the
Purchaser shall deliver or cause to be delivered to the Seller, the following:

 

		(a)	all documentation and other evidence reasonably requested by the Seller in order to establish the
due authorization and completion of the transactions contemplated by this Agreement, including the taking of all corporate proceedings
by the board of directors and shareholders of the Purchaser and the Corporation required to effectively carry out the obligations
of the Purchaser pursuant to this Agreement;

 

		(b)	the consulting agreement between the Corporation, Bill Dickie and WJD Associates Inc., signed by
the Corporation; and

 

		(c)	documentation, satisfactory to the Seller, evidencing the termination of the Shareholders Agreement.

 

Article 7

GENERAL

 

		7.1	Further Assurances

 

Each Party shall execute
and deliver such further documents, instruments of conveyance and transfer and take such additional action as the other Parties
may reasonably request to confirm or evidence the transfer of the Purchased Shares or to otherwise carry out or better evidence
or perfect the full intent and meaning of this Agreement.

 

		7.2	Costs and Expenses

 

Unless otherwise specified,
each Party shall be responsible for all costs and expenses (including the fees and disbursements of legal counsel, bankers, investment
bankers, accountants, brokers and other advisors) incurred by it in connection with this Agreement and the transactions contemplated
by it.

 

		7.3	Public Announcements

 

No public announcement or
press release concerning the purchase and sale of the Purchased Shares shall be made by the Purchaser or the Seller without the
consent and approval of the other Party; provided, however, that each of the Parties shall be permitted to disclose
the transactions contemplated by this Agreement to each of such Party’s direct or indirect shareholders, members or partners,
as applicable, to the extent required by law or in a manner consistent with such Party’s past practices.

 

		7.4	Assignment

 

Except as provided in this
Section 7.4, neither this Agreement nor any of the rights, benefits or obligations under this Agreement are assignable or transferable
by either Party without the prior written consent of the other Party which consent shall not be unreasonably withheld. The
Purchaser may assign its rights, benefits and obligations under this Agreement, in whole or in part, to

 

    	 	26

    	 

    

 

any person that acquires
all or substantially all of the assets of the Purchaser or acquires a majority of the Purchaser’s issued and outstanding
voting securities, whether by way of take-over bid, amalgamation, arrangement, merger or otherwise.

 

		7.5	Notices

 

Any demand, notice or other
communication to be made or given in connection with this Agreement shall be made or given in writing and may be made or given
by personal delivery, by courier or by transmittal by fax or e-mail addressed as follows:

 

		(a)	if to the Purchaser, to:

 

20 rue Diesel

01630 Saint Genis Pouilly,

France

 

		Facsimile:	+33 4 50 99 30 71

		Attention:	Stefano Buono, CEO of AAA

		E-Mail:	stefano.buono@adacap.com

 

with a copy to:

 

Dentons Canada LLP

99 Bank Street, Suite 1420

Ottawa ON K1P 1H4

 

		Facsimile:	(613) 783-9690

		Attention:	Thomas A. Houston

		E-Mail:	tom.houston@dentons.com 

 

		(b)	if to the Seller, to:

 

9 Hansen Avenue,

Kanata, Ontario K2K 2L9

 

		Facsimile:	(613) 212-8990

		Attention:	Chief Executive Officer

		E-Mail:	bdickie@atreuspharma.com

 

with a copy to:

 

LaBarge Weinstein LLP

800-515 Legget Drive

Ottawa ON K2K 3G4

 

    	 	27

    	 

    

 

		Facsimile:	(613) 599-0018

		Attention:	Estelle Duez

		E-Mail:	eduez@lwlaw.com

 

or to such other address,
fax number, e-mail address or individual as may be designated by notice by any Party to the others. Any demand, notice or other
communication made or given by personal delivery shall be conclusively deemed to have been given on the day of actual delivery
thereof and, if made or given by courier, on the second (2nd) business day following the deposit thereof with the courier
and, if made or given by fax or e-mail, on the day of transmittal thereof or if the day of transmittal is not a business day, the
next business day following the date of transmittal thereof (provided the original copy is immediately forwarded by courier).

 

		7.6	Governing Law

 

This Agreement shall be governed
by and construed in accordance with the laws of the Province of Ontario, without regard to the province’s conflict of law
provisions, and each of the Parties hereto irrevocably agrees to submit to the exclusive jurisdiction of the courts of such province
located in Ottawa, Ontario for and in connection with any proceedings relating to this Agreement.

 

		7.7	Benefit of Agreement

 

This Agreement shall enure
to the benefit of and be binding upon the Parties and their respective successors and permitted assigns.

 

		7.8	Amendment and Waiver

 

This Agreement may not be
amended, supplemented or otherwise modified in any respect except by written agreement signed by the Parties. Any waiver of any
of the provisions of this Agreement will be binding only if it is in writing and signed by the Party to be bound by it, and only
in the specific instance and for the specific purpose for which it has been given. The failure or delay of any Party in exercising
any right under this Agreement will not operate as a waiver of that right. No single or partial exercise of any right will preclude
any other or further exercise of that right or the exercise of any other right, and no waiver of any of the provisions of this
Agreement will constitute a waiver of any other provision (whether or not similar).

 

		7.9	Entire Agreement

 

This Agreement constitutes
the entire agreement between the Parties hereto with respect to the subject matter hereof and cancels and supersedes any prior
understandings and agreements between the Parties hereto with respect thereto. There are no representations, warranties, terms,
conditions, undertakings or collateral agreements, express, implied or statutory, between the Parties other than as expressly set
forth or contemplated in this Agreement.

 

		7.10	Severability

 

If any provision of this
Agreement is determined to be invalid or unenforceable in whole or in part, such invalidity or unenforceability shall attach only
to such provision or part thereof and the remaining part of such provision and all other provisions hereof shall continue in full
force and effect.

 

    	 	28

    	 

    

 

		7.11	Counterparts and Execution by Electronic Means

 

This Agreement may be executed
by the Parties in separate counterparts, each of which, when so executed and delivered, shall be deemed to constitute an original,
but all of which together shall constitute one and the same agreement. This Agreement may be executed by facsimile or PDF and the
delivery by facsimile or PDF of signed copies of this Agreement shall constitute and be deemed to be delivery of the original signatures
of the Parties.

 

The remainder of this page
is intentionally left blank.

 

    	 	29

    	 

    

 

IN WITNESS WHEREOF the Parties
have executed this Agreement on and as of the day first above written.

 

	 	AAA INTERNATIONAL S.A.
	 	 
	 	By:	/s/ Gérard Ber
	 	 	Name: Gérard Ber
	 	 	Title: Chief Executive Officer

 

	 	ADVANCED ACCELERATOR APPLICATIONS S.A.
	 	 
	 	By:	/s/ Stefano Buono
	 	 	Name: Stefano Buono
	 	 	Title: Chief Executive Officer

 

	 	7329563 CANADA INC.
	 	 
	 	By:	/s/ William J. Dickie
	 	 	Name: William J. Dickie
	 	 	Title: Director

 

[SIGNATURE PAGE TO SHARE PURCHASE AGREEMENT]

 

    	 

    	 

    

 

SCHEDULE “A”

 

Annual Financial Statements

 

See attached.

 

    	 

    	 

    

 

SCHEDULE “B”

 

Interim Financial Statements

 

See attached.

 

    	 

    	 

    

 

SCHEDULE “C”

 

Disclosure Schedule

 

See attached.

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