Document:

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EXHIBIT 10.1

June 30, 2004

David Kirske

Dear David:

Our Board of Directors, our management team, and I are confident you possess the
experience and qualifications we are seeking to assist us in making the Company
a highly successful business. On behalf of Helix BioMedix, Inc. (the "Company")
we are pleased to offer you the position of Vice-President and Chief Financial
Officer on the following terms and conditions.

Subject to the fulfillment of any conditions imposed by this letter, the terms
of your position with the Company will be as set forth below:

1. POSITION:

You will be Vice-President and Chief Financial Officer, working out of the
Company's headquarters office in Bothell, Washington. As such, you will have
responsibility for overseeing all aspects of the Company's accounting and
finance requirements, including reporting under the 1933 Securities Act and the
1934 Securities Exchange Act and initially report to R. Stephen Beatty.

You agree to the best of your ability and experience that you will at all times
loyally, honestly, and conscientiously perform all of the duties and obligations
required of and from you pursuant to the express and implicit terms hereof.
During the term of your employment, you further agree that you will devote all
of your business time and attention to the business of the Company, the Company
will be entitled to all of the benefits and profits arising from or incident to
all such work services and advice, you will not render commercial or
professional services of any nature to any person or organization, whether or
not for compensation, without the prior written consent of the Company, and you
will not directly or indirectly engage or participate in any business that is
competitive in any manner with the business of the Company. Notwithstanding the
preceding sentence, we acknowledge and consent to the fact that, during the
months of July and August 2004 you will be providing consulting services on a
one-day a week basis to Blood Cell Storage, Inc. Our consent to that consulting
relationship is subject to you providing us with a copy of an agreement pursuant
to which that relationship is terminated on or before August 31, 2004. Nothing
in this letter agreement will prevent you from accepting speaking or
presentation engagements in exchange for honoraria or from serving on Board of
Directors of organizations that are not in a competitive posture with the
Company.

2. START DATE:

We would like for you to commence your employment with the Company on July 1,
2004.

3. PROOF OF RIGHT TO WORK:

For purposes of Federal immigration law, you will be required to provide the
Company with documentary evidence of your identity and eligibility for
employment in the United States. Such documentation must be provided to us
within three (3) business days of your date of hire, or our employment
relationship with you may be terminated.

4. COMPENSATION:

BASE SALARY:

You will be paid a monthly salary of $12,500.00. Your position is classified as
exempt and, as such, you will not be eligible for overtime pay. Your salary will
be payable every other week pursuant to the Company's regular payroll policy
including standard withholding such as Medicare and social security taxes.

HEALTH, MEDICAL, AND LIFE INSURANCE BENEFITS:

You and your family will be eligible to participate in the Company's health,
medical, and life insurance plans that will be described to you in detail under
separate cover. We provide a competitive health, medical insurance, and life
insurance plan to the Company's employees.

<PAGE>

ANNUAL REVIEW:

Your base salary will be reviewed at the end of each calendar year as part of
the Company's normal salary review process, commencing December 2004.

5. STOCK OPTION GRANT:

In connection with the commencement of your employment, the Company will
recommend that the Board of Directors grant you an option to purchase 180,000
shares of the Company's common stock with an exercise price equal to the fair
market value on the date of the grant. These option shares will vest over a
three-year period in six (6) equal installments of 30,000 shares on the last day
of each six (6) month period commencing on December 31, 2004.

The option will be an incentive stock option to the maximum extent allowed by
the Federal tax code and will be subject to the terms of the Company's 2000
Stock Option Plan and the Incentive Stock Option Agreement between you and the
Company.

6. ARBITRATION AGREEMENT/ PIAA/CONFIDENTIALITY OF TERMS:

Upon commencement of your employment with the Company, you agree to execute and
deliver to the Company its standard forms of arbitration agreements and
proprietary invention and assignment agreement. You also agree not to disclose,
either directly or indirectly, any information, including any of the terms of
this agreement, regarding salary, bonuses, or stock purchases or option
allocations to any person, including other employees of the Company; provided,
however, that you may discuss such terms with members of your immediate family
and any legal, tax, or accounting specialists who provide you with individual
legal, tax, or accounting advice.

7. AT-WILL EMPLOYMENT:

Your employment with the Company will be on an "at will" basis, meaning that
either you or the Company may terminate your employment at any time for any
reason or no reason, without further obligation or liability. Notwithstanding
the foregoing, in the event that, during the first three (3) years of your
employment relationship, the Company terminates this employment relationship
without cause (as defined below), the Company will pay you a severance benefit
equal to six months of your then current base monthly salary. For purposes of
the immediately preceding sentence the term "cause" shall means if you: (i) are
convicted of a felony or any crime involving dishonesty, breach of trust, or
physical harm to any person or relating to the business of the Company or any
successor company (or enter a pleas of guilty or nolo contendere with respect
thereto); (ii) repeatedly report to work under the influence of alcohol or
illegal drugs; (iii) substantially and repeatedly fail to perform the duties as
reasonably directed by the President of the Company or any successor company,
(iv) are found by a court of competent jurisdiction to have made unauthorized
use or disclosure of confidential information or trade secrets; or (v) engage in
gross negligence or willful misconduct in carrying out your duties as an
employee of the Company or any successor company.

To indicate your acceptance of the Company's offer, please sign and date this
letter in the space provided below and return it to me. This letter, together
with the PIIA referenced above, set forth the terms of your employment with the
Company and supercedes any prior representations or agreements, whether written
or oral. This letter may not be modified or amended except by a written
agreement, signed by the Company and by you.

                                   HELIX BIOMEDIX, INC.

Dated: July 2, 2004

                                   By: /s/R. Stephen Beatty
                                   -------------------------------------------
                                   R. Stephen Beatty
                                   President and Chief Executive Officer

                                   /s/David H. Kirske
                                   -------------------------------------------
                                   David H. Kirske
                                   Vice President and Chief Financial Officer<PAGE>

EXHIBIT 10.2

August 12, 2004

David Drajeske

Dear David:

Our Board of Directors, our management team, and I are confident you possess the
experience and qualifications we are seeking to assist us in making the Company
a highly successful business. On behalf of Helix BioMedix, Inc. (the "Company")
we are pleased to offer you the position of Vice-President - Business
Development on the following terms and conditions.

Subject to the fulfillment of any conditions imposed by this letter, the terms
of your position with the Company will be as set forth below:

1. POSITION:

You will be Vice-President - Business Development, working out of the Company's
headquarters office in Bothell, Washington. As such, you will have
responsibility for overseeing all aspects of the Company's business development
initiatives and initially report to R. Stephen Beatty.

You agree to the best of your ability and experience that you will at all times
loyally, honestly, and conscientiously perform all of the duties and obligations
required of and from you pursuant to the express and implicit terms hereof.
During the term of your employment, you further agree that you will devote all
of your business time and attention to the business of the Company, the Company
will be entitled to all of the benefits and profits arising from or incident to
all such work services and advice, you will not render commercial or
professional services of any nature to any person or organization, whether or
not for compensation, without the prior written consent of the Company, and you
will not directly or indirectly engage or participate in any business that is
competitive in any manner with the business of the Company. Nothing in this
letter agreement will prevent you from accepting speaking or presentation
engagements in exchange for honoraria or from serving on Board of Directors of
organizations that are not in a competitive posture with the Company.

2. START DATE:

We would like for you to commence your employment under the terms set forth in
this letter agreement on July 1, 2004.

3. PROOF OF RIGHT TO WORK:

For purposes of Federal immigration law, you will be required to provide the
Company with documentary evidence of your identity and eligibility for
employment in the United States. Such documentation must be provided to us
within three (3) business days of your date of hire, or our employment
relationship with you may be terminated.

4. COMPENSATION:

BASE SALARY:

You will be paid a monthly salary of $12,500.00. Your position is classified as
exempt and, as such, you will not be eligible for overtime pay. Your salary will
be payable every other week pursuant to the Company's regular payroll policy
including standard withholding such as Medicare and social security taxes.

UPFRONT BONUS:

Upon your agreement with this letter agreement, we will pay to you an
unconditional-upfront bonus in the amount of $25,000.00 subject, of course, to
withholding obligations.

<PAGE>

HEALTH, MEDICAL, AND LIFE INSURANCE BENEFITS:

You and your family will be eligible to participate in the Company's health,
medical, and life insurance plans that will be described to you in detail under
separate cover. We provide a competitive health, medical insurance, and life
insurance plan to the Company's employees.

ANNUAL REVIEW:

Your base salary will be reviewed at the end of each calendar year as part of
the Company's normal salary review process, commencing December 2004.

5. STOCK OPTION GRANT:

In connection with the commencement of your employment, the Company will
recommend that the Board of Directors grant you an option to purchase 180,000
shares of the Company's common stock with an exercise price equal to the fair
market value on the date of the grant. These option shares will vest over a
three-year period in six (6) equal installments of 30,000 shares on the last day
of each six (6) month period commencing on December 31, 2004.

The option will be an incentive stock option to the maximum extent allowed by
the Federal tax code and will be subject to the terms of the Company's 2000
Stock Option Plan and the Incentive Stock Option Agreement between you and the
Company.

6. ARBITRATION AGREEMENT/ PIAA/CONFIDENTIALITY OF TERMS:

Upon commencement of your employment with the Company, you agree to execute and
deliver to the Company its standard forms of arbitration agreements and
proprietary invention and assignment agreement. You also agree not to disclose,
either directly or indirectly, any information, including any of the terms of
this agreement, regarding salary, bonuses, or stock purchases or option
allocations to any person, including other employees of the Company; provided,
however, that you may discuss such terms with members of your immediate family
and any legal, tax, or accounting specialists who provide you with individual
legal, tax, or accounting advice.

7. AT-WILL EMPLOYMENT:

Your employment with the Company will be on an "at will" basis, meaning that
either you or the Company may terminate your employment at any time for any
reason or no reason, without further obligation or liability. Notwithstanding
the foregoing, in the event that, during the first three (3) years of your
employment relationship, the Company terminates this employment relationship
without cause (as defined below), the Company will pay you a severance benefit
equal to six months of your then current base monthly salary. For purposes of
the immediately preceding sentence the term "cause" shall means if you: (i) are
convicted of a felony or any crime involving dishonesty, breach of trust, or
physical harm to any person or relating to the business of the Company or any
successor company (or enter a pleas of guilty or nolo contendere with respect
thereto); (ii) repeatedly report to work under the influence of alcohol or
illegal drugs; (iii) substantially and repeatedly fail to perform the duties as
reasonably directed by the President of the Company or any successor company,
(iv) are found by a court of competent jurisdiction to have made unauthorized
use or disclosure of confidential information or trade secrets; or (v) engage in
gross negligence or willful misconduct in carrying out your duties as an
employee of the Company or any successor company.

To indicate your acceptance of the Company's offer, please sign and date this
letter in the space provided below and return it to me. This letter, together
with the PIIA referenced above, set forth the terms of your employment with the
Company and supersedes any prior representations or agreements, whether written
or oral. This letter may not be modified or amended except by a written
agreement, signed by the Company and by you.

HELIX BIOMEDIX, INC.                       By: /s/R. Stephen Beatty
                                           -------------------------------------
Dated: August 12, 2004                     R. Stephen Beatty
                                           President and Chief Executive Officer

                                           /s/David Drajeske
                                           -------------------------------------
                                           Vice President, Business Development

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