Document:

Master Clinical Services Agreement

 Exhibit 10.28 
 MASTER CLINICAL SERVICES AGREEMENT 
 by and between 
 NEUROBIOLOGICAL TECHNOLOGIES, INC. 
 and 
 ICON CLINICAL RESEARCH LIMITED 
 This Master Clinical Services Agreement (this “Agreement”) is made as of January 16, 2007 by and between Neurobiological Technologies, Inc., a Delaware corporation with an address of 2000 Powell Street,
Suite 800, Emeryville, CA 94608 (“Sponsor”), and ICON Clinical Research Limited, a company formed under the laws of Ireland with offices at South County Business park, Leopardstown, Dublin, Ireland (“Service Provider”).

 WITNESSETH 
 WHEREAS,
Sponsor has now and from time to time in the future may have the desire to engage Service Provider for research or clinical services and 
 WHEREAS, Service Provider would like to provide such services on the terms and conditions set forth herein. 
 NOW THEREFORE, in
consideration of the premises and of the mutual promises and covenants herein contained, the adequacy of which is acknowledged by each of the parties, the parties hereto agree as follows: 
  

	1.	SERVICES AND PERSONNEL 

 1.1 General. Service Provider shall use its
best commercial efforts to diligently provide all the services reasonably helpful for the successful completion of each project (“Project”) set forth in a Work Order (“Services”) to Sponsor in accordance with this Agreement, to
keep Sponsor fully advised of the progress of the work, to provide Sponsor with such reports, specifications, and the like, as and when reasonably requested by Sponsor. 
 1.2 Affiliates. Sponsor and Service Provider agree that their respective Affiliates may also execute Work Orders under this Agreement. Furthermore Sponsor agrees that Service Provider may use the services of
its Affiliates to fulfill Service Provider’s obligations under this Agreement. Any Affiliate(s) so used shall be subject to all of the terms and conditions applicable to the respective party under this Agreement. Service Provider hereby
authorizes any of its Affiliates to execute Work Orders in connection herewith and such Work Orders shall be deemed to have full force and effect as if executed by Service Provider. Service Provider shall be fully responsible for all the acts or
omissions of its Affiliates and their fulfillment of the terms and conditions of this Agreement and any Work Orders. For the purposes of this Agreement and any Work Order hereunder “Affiliate” shall mean any entity, which controls, is
controlled by, or is under common control with that party. In this context “control” shall mean (1) ownership by one entity, directly or indirectly, of at least fifty percent (50%) of the voting stock of another entity,
(2) power of one entity to direct the management or policies of another entity by contract or otherwise, or (3) any other relationship between a party and an entity which both Sponsor and Service Provider have agreed in writing may be
considered an “affiliate” of a party. 
  

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 1.3 Work Order. Services provided by Service Provider shall be subject to the terms and conditions of this
Agreement. All such Services shall be the subject of a work order, substantially in the form of Exhibit A, setting forth the following with respect to the applicable Project: (i) description of Services to be provided, (ii) fee and payment
schedule for the Services, (iii) description of deliverables to be delivered by Service Provider (each, a “Deliverable) and related specifications, (iv) materials to be provided by each party and (v) a Project timeline. After a
work order substantially in the form of Exhibit A is agreed upon and executed by the parties hereto, the same shall be attached to this Agreement as an amendment to Exhibit B (each, a “Work Order”) and the Work Order shall
then be a part of this Agreement. There will be no limit to the number of Work Orders that may be added to this Agreement. Services shall only be commenced after the execution of a Work Order by both parties. In the event of any conflict between the
terms of any Work Order and Sections 1 – 11 of this Agreement, then the terms set forth in Sections 1 – 11 of this Agreement (excluding any that require the incorporation of the conflicting term) shall govern. 
 1.4 Change Orders. In the event that Sponsor would like Service Provider to materially alter the Services under a given Work Order or the assumptions underlying
the budget, (including, but not limited to, changes in an agreed starting date for services or suspension of some or all of the Services, by the Sponsor; a delay in the provision of needed Study materials or needed information by a party; or any
delays caused by a party), the parties shall agree upon a written change order (“Change Order”) prior to the provision of said Services. The Change Order constitutes an amendment to the applicable Work Order and the additional or amended
services set forth therein shall be deemed to be Services part of such Work Order. Any unauthorized changes in scope made by Service Provider shall be the responsibility of Service Provider and Service Provider agrees to pay to Sponsor any of its
losses related thereto. Service Provider has no obligation to perform and Sponsor has no obligation to pay for any additional or modified Services absent written agreement by the parties with respect thereto. 
 1.5 Core Team. Service Provider will assign a project manager (the “Project Manager”) and other members of the core Project team agreed by the parties
(including, as relevant, a project director) (the “Core Team”) for the duration of each project for which a Work Order has been authorized. Service Provider agrees to provide thirty (30) days prior written notice to Sponsor, whenever
practicable, of any changes to the Core Team, except as specified below. During any Project, Service Provider will employ its commercially reasonable efforts to promote members of the Core Team within the Project. Service Provider agrees to obtain
the consent of Sponsor to any changes to the relevant Core Team (other than as a result of death or disability or illness or promotion, or if the Core Team member is no longer an employee or agent of Service Provider), which consent shall not be
unreasonably withheld, delayed, or conditioned. Service Provider will provide Project-specific training to replacement Core Team members at its own expense. The Project Manager, or such other Core Team Member agreed by the parties, shall be the
primary contact for Sponsor and shall timely address all issues and concerns raised by Sponsor, as well as provide to Sponsor all information requested by Sponsor concerning this Agreement or the Services. In the event (i) Service Provider
becomes aware that a Core Team member plans to 

  

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leave the employment of Service Provider or shall be unable to complete the Services due to dismissal, death or disability or illness or promotion, it shall
give prompt written notice of the same to Sponsor or (ii) Sponsor is not reasonably satisfied with the services of Core Team member, Sponsor shall give notice of the same to Service Provider. If Service Provider and Sponsor are unable to
mutually agree upon a substitute Core Team member within a period of thirty (30) days following the date of the written notice, this Agreement or the affected Work Order may be immediately terminated by Sponsor for material breach of Service
Provider upon written notice to Service Provider pursuant to Section 6.2(a)(ii). 
 1.6 Nonconforming Services. Notwithstanding anything to the
contrary herein, if due to the acts or omissions of Service Provider, it provides any deliverable or Services that materially fail to conform to the specifications of Sponsor, including those set forth in the applicable Work Order and any reasonable
written instructions of Sponsor, in addition to any rights or remedies Sponsor may have available to it, Sponsor may require Service Provider to (i) conform such Services to the specifications of Sponsor at no additional cost to Sponsor or
(ii) if Service Provider does not or cannot promptly conform such Services, credit to Sponsor any monies paid by Sponsor to Service Provider for the performance of such Services and the additional reasonable cost incurred by Sponsor in
connection with causing the Services to conform to the relevant specifications of Sponsor. 
 1.7 Service Provider Personnel. All employees and agents
of Service Provider that perform Services under this Agreement are employees and agents, respectively, of Service Provider and not Sponsor during the term of this Agreement and shall at all times be directed solely by Service Provider.
Notwithstanding Sponsor’s obligation to reimburse certain costs pursuant to Section 3 hereof, Service Provider will be responsible for payment to its employees and agents of all salaries, wages, benefits, other compensation, reimbursable
travel, lodging, and other expenses to which the employees or agents may be entitled to receive for performing Services. Service Provider will be solely responsible for withholding and paying all applicable payroll taxes of any nature, including,
without limitation, social security and other social welfare taxes or contributions, that may be due on amounts paid to employees or agents. To the extent that any Services are performed on the premises of Sponsor, Service Provider will cause each
of its employees and agents involved in providing any Services to Sponsor to comply with Sponsor’s then-current workplace rules, security procedures and confidentiality policies and procedures for the Sponsor facility where such employee or
agent performs Services. 
 1.8 Initiation, Accrual, and Completion. Service Provider shall exercise all reasonable diligence to meet and maintain
site initiation, subject accrual, and subject completion rates and timing set forth in a Work Order. Sponsor shall have the right to terminate performance under a Work Order if due to the actions or inactions of the Service Provider such initiation,
accrual, or completion rates and timing do not materially reach and maintain levels agreed in the Work Order. Any such termination shall be deemed a termination by Sponsor pursuant to Section 6.2(a)(ii). All study sites and investigators shall
be subject to the prior written approval of Sponsor. 
 1.9 Laboratory Services. If Service Provider laboratory services are to be utilized by
Sponsor, such services will be invoiced separately, in accordance with Exhibit C, and as results are reported, together with other fees including but not limited to initial set-up, investigator manuals, data transfer fees. 
  

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	2.	REPRESENTATIONS, WARRANTIES AND COVENANTS 

 Service Provider represents,
warrants and covenants to Sponsor as follows. 
 2.1 Formation/Power and Authority. Service Provider is duly formed and validly existing under the
laws of its jurisdiction of formation and has all requisite power and authority, in each jurisdiction in which Services will be performed, to own and operate its business and properties and to carry on its business as such business is now being
conducted and to execute and deliver this Agreement and to perform its obligations hereunder. 
 2.2 No Conflict. The execution, delivery and
performance of this Agreement by Service Provider and the consummation of the transactions contemplated hereby do not and will not contravene the formation documents of Service Provider and do not and will not conflict with or result in a breach of
or default under any agreement to which it is a party that would have a material adverse effect on Service Provider’s ability to perform its obligations under this Agreement. 
 2.3 Compliance with Applicable Law. Service Provider represents and warrants that it is in full compliance at all times and will continue to be in compliance at all times with all applicable U.S. or foreign
laws, rules, regulations, guidelines and industry standards, including those of the U.S. Food and Drug Administration (the “FDA”); good clinical practice guidelines of the FDA; the International Conference on Harmonization E6 Good Clinical
Practice (“ICHGPC”) guidelines; Clinical Laboratory Improvement Amendments; 21 CFR Part 11; and any other relevant U.S. or foreign regulatory or governmental authority (“Applicable Law”). Service Provider shall not violate, or
cause Sponsor to be in violation of, the U.S. Foreign Corrupt Practices Act. 
 2.4 Report of Noncompliance. Should noncompliance of an employee,
agent, investigator or study site with Applicable Law, this Agreement or any applicable agreement be discovered by or come to the attention of Service Provider, Service Provider will immediately notify Sponsor and appropriate action will be taken by
Service Provider. Any such action shall be taken after consultation with Sponsor and at Sponsor’s expense. 
 2.5 Experience/Timeliness. Service
Provider, its employees and agents, have and will continue to have the knowledge, experience and skill to provide, and will provide, the Services in a professional and timely manner. Service Provider will staff each Project sufficiently to ensure
the completion of the Project in accordance with this Agreement. 
 2.6 Workmanship. Services will conform to the industry accepted standards of
workmanship and the specifications for the Project. 
 2.7 Performance. Service Provider will perform all Services in accordance with this Agreement,
Applicable Law, each applicable protocol (each, a “Protocol”), standard operating procedures approved by Sponsor and the reasonable written instructions of Sponsor. 
  

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 2.8 Deliverables. Each Deliverable delivered in connection herewith shall be in accordance with the specifications
set out in the applicable Work Order. 
 2.9 Permits. Prior to commencement of a Project, Service Provider will identify all permits and approvals
necessary or helpful in connection with the conduct and successful completion of such Project. The parties shall indicate in the Work Order which party will be responsible for procuring and maintaining each such permit and approval. Unless
impossible, expressly prohibited by Applicable Law or otherwise requested by Sponsor in writing, Service Provider shall procure and maintain in the name of Sponsor all permits and approvals for which it is responsible. 
 2.10 No Encumbrance. Service Provider hereby (i) acknowledges and agrees that neither it, nor any of its affiliates or subsidiaries, nor any of its or their
directors, officers, employees and agents has any interest in Sponsor Data or Inventions (each as defined below) and (ii) covenants that it will not lien or encumber, or otherwise cause, permit or consent to the granting of a lien or
encumbrance of the Sponsor Data or Inventions. 
 2.11 Freedom to Use. Excluding Service Provider’s Property, to Service Provider’s
knowledge, Sponsor may freely use, practice, reproduce, distribute, make and sell all intellectual property rights and any other advice, data, information, inventions, works of authorship or know-how, including Sponsor Data, Inventions and any
Deliverables, that Service Provider conveys or provides hereunder without restriction and without infringing or misappropriating any third party’s (e.g., a university or corporation) intellectual property or other rights. 
 2.12 Debarment. Service Provider hereby certifies it does not and shall not employ, contract with or retain any person to perform Services under this Agreement if
such person is debarred under 21 U.S.C. 335a (a) or (b) or other equivalent laws, rules, regulations or standards of any other relevant jurisdiction. Upon written request of Sponsor, Service Provider shall, within ten (10) business
days, provide written confirmation that it has complied with the foregoing obligation. Service Provider agrees to promptly disclose in writing to Sponsor if any employee or agent performing, or who has performed, the Services is debarred, or if any
action or investigation is pending or, to the best of Service Provider’s knowledge, threatened, relating to the debarment of Service Provider or any person performing services related to this Agreement. 
 2.13 Disclosures. Service Provider shall also provide all information to Sponsor requested by Sponsor to comply with any disclosure requirements of Applicable
Law, including any information required to be disclosed in connection with any financial relationship between Sponsor and Service Provider. Service Provider shall disclose to Sponsor any financial interest, other than the payment for Services agreed
to hereunder, that Service Provider might have in any Project. 
 2.14 Inspections. Service Provider agrees to permit representatives of the FDA or
any other relevant regulatory or governmental authority to access at any reasonable time during normal business hours relevant records, information (and, where applicable, make copies of the same), personnel and facilities. 
  

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 2.15 Scheduling of Inspections. Service Provider shall within one business day notify Sponsor if the FDA or other
governmental authority schedules or, without scheduling, begins an inspection or audit relating to Services. Service Provider shall make every reasonable effort to permit Sponsor to be present at or participate in such inspection or audit if the
same relates to this Agreement or Services. In addition, Service Provider will promptly provide Sponsor copies of any correspondence from or to the FDA or other regulatory authorities relating to this Agreement or any Services. 
 2.16 Electronic Systems. Service Provider represents and warrants that all computer systems and electronic records used by Service Provider or delivered to
Sponsor: (i) have been or, with respect to systems and records yet to be used or delivered, shall have been, upon use or delivery, developed, validated, established and maintained in full accordance with Applicable Law, including, without
limitation, 21 CFR Part 11, as may be amended or superseded from time to time; (ii) are not subject to any known errors, anomalies or impairment in connection with the use, calculation, representation or handling of any form of date related
information; (iii) are free of any known computer viruses or other harmful programming which might impair Sponsor’s full and unconditional use of such electronic records; and (iv) are free of any lien or license or any requirement to
obtain any license for their use (except for such readily available software licenses required in the ordinary course of business for the products used to handle and use such electronic records). With respect to any systems and records to be used by
or delivered to Sponsor which are not validated as of the date hereof, Service Provider has in place a compliance plan for the validation of such systems or records to ensure compliance with Applicable Law prior to such use or delivery. 

Sponsor represents, warrants and covenants to Service Provider as follows. 
 2.17 Compliance with Applicable Law. Sponsor represents and warrants that it will comply with Applicable Law in the fulfillment of its duties hereunder. Sponsor shall not violate, or cause Service Provider to be in violation of, the
U.S. Foreign Corrupt Practices Act. 
 2.18 License. Sponsor warrants that it has the right to have the Services performed and the Deliverables
delivered. 
 2.19 Freedom to Use. To Sponsor’s knowledge, Service Provider may, for the purposes of this Agreement and any Work Order
promulgated hereunder, use the Confidential Information provided to it for use in the performance of the Services. 
  

	3.	COMPENSATION 

 3.1 Generally. The fees for Services and estimated
pass-through costs to be paid to Service Provider in connection with the Services are contained in each Work Order. Service Provider acknowledges that it has included all of its costs and estimated costs (including pass-through costs), in
calculating the fee and costs for the Services budget attached hereto as part of the applicable Work Order and that Sponsor shall not be liable for any other fees. No fee line item in any budget shall be exceeded by Service Provider without the
prior written consent of Sponsor. All budgets shall detail out-of-pocket costs, associated overhead allocations, and the basis for budget calculations. 
  

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 3.2 Invoicing and Payment. All invoices and payments hereunder shall be in U.S. Dollars, unless otherwise agreed
to in the relevant Work Order (the “Contract Currency”). Payments will be made payable to Service Provider at the address above. If Service Provider’s fees have been costed in another currency, conversion to the Contract Currency will
be made at a fixed price set out in the budget in the relevant Work Order. There will be no adjustments to the conversion rate for the first twelve (12) months of the term of each Work Order. Thereafter, a party may request that the conversion
rate be adjusted for a Work Order, provided that such rate has fluctuated by greater than four percent (4%) since the original Work Order or most recent adjustment, as the case may be. In such event, the parties agree to make the adjustment.
Unless otherwise agreed in the payment schedule for the relevant Work Order, invoices shall be submitted by Service Provider to Sponsor on a monthly basis and, except with respect to amounts subject to a bona fide dispute, payment will be made by
Sponsor within thirty (30) days after receipt by Sponsor of Service Provider’s monthly invoice. 
 3.3 Taxes. All income taxes, VAT, levies,
surcharges, withholding, or other similar charges and any penalties levied thereon which relate to any amounts paid to Service Provider (excluding agreed pass-through expenses and investigator payments) hereunder shall be the responsibility of and
paid by the Service Provider. 
 3.4 Service Provider’s Fees for Performance of Services. The Service Provider’s fees for the performance of
Services represent the entire cost for the provision of the Services. Service Provider shall not charge Sponsor for (a) any Services, Deliverables, or costs set forth in a Work Order or other agreement of the parties, but not materially
performed or delivered to Sponsor in accordance with this Agreement or (b) any Services, Deliverables or costs that were not contracted in connection the relevant Project. All budgets shall include all costs of permitted subcontractors and
affiliates, it being understood that investigators at study sites not owned or controlled by Service Provider are not subcontractors of Service Provider. 
 3.5 Pass-through Costs. If applicable, Service Provider will provide an estimated pass-through budget in each Work Order. The budget shall constitute Service Provider’s best good faith estimate of all pass-through costs for the
relevant Project. Prior to exceeding any material pass-through cost which is not clearly specified in the estimated pass through costs, Service Provider will contact Sponsor for prior approval All pass-through costs invoiced to Sponsor will be at
actual cost with no mark-up for administrative, overhead, or other similar fees. Upon good cause, but not on a regular basis without cause, Sponsor shall be permitted to request and Service Provider will provide back-up documentation reasonably
acceptable to Sponsor. In the event Service Provider incurs a pass-through cost in a currency other than Contract Currency, the parties shall determine the amount payable based on the applicable currency exchange rate as published at Oanda.com on
the first Monday of the month in which the costs were incurred. All pass-through expenses shall be invoiced to Sponsor and paid within fifteen (15) days of receipt of invoice. It is acknowledged and accepted by Sponsor that Service Provider
shall not make any investigator payments until it has received funds for the same from Sponsor. 
  

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	4.	SPONSOR DATA, PREEXISTING TECHNOLOGY AND INVENTIONS 

 4.1 Ownership of
Sponsor Data and Inventions. Excluding Service Provider’s Property, all (i) data, images, information, documents, records in whatever form obtained, developed, recorded or compiled in connection with this Agreement or any Work Order
relating to the Services (“Sponsor Data”) and (ii) technology, inventions, discoveries and improvements, whether patentable or not, developed or conceived in connection with this Agreement and relating to the Services, including,
without limitation, any technology, inventions, discoveries and improvements relating to a relevant study, protocol, the study drug, or any chemicals structurally related to such study drug, or the use, formulation, manufacture, administration,
dosing, mechanism, or composition of such study drug or chemical (“Inventions”) are and shall remain the sole and exclusive property of Sponsor. Service Provider shall immediately deliver any such property to Sponsor. Service Provider and
the Project Manager agree that they will not file any patent applications with respect to any Sponsor Data or Invention. 
 4.2 Disclosure and
Assignment. With respect to all Sponsor Data and Inventions, Service Provider and Project Manager agree (i) to disclose the same promptly to Sponsor; (ii) to execute documents evidencing the rights set forth herein; and (iii) upon
the request of Sponsor and at the sole expense, discretion and exclusive control of Sponsor, to apply, or to assist and cooperate with Sponsor in applying for, letters patent or like corresponding legal protection of any such Sponsor Data and
Inventions in the United States and all foreign countries (and for any extension, continuation, validation, reissue or renewal thereof). For that purpose, Service Provider and Project Manager agree to execute, and Sponsor agrees to cause its
employees and agents to execute, all papers necessary therefor, including assignments to Sponsor or its nominee, without consideration, and also agree without further consideration, but at Sponsor’s expense, to provide such information as may
be required by Sponsor and to assist Sponsor, or its agents or designees, in the preparation and prosecution of any such patent application, the enforcement of any such resulting patent and the protection of any such invention or discovery.

 4.3 Service Provider’s Property. Any inventions, processes, know-how, trade secrets, improvements, other intellectual properties and other
assets, including but not limited to customers, contractors and suppliers lists, analytical methods, designs, procedures and techniques, procedure manuals, personnel data, financial information, computer technical expertise and software, which have
been developed by the Service Provider independently of this Agreement, any Work Order, and Confidential Information, and which relate to its business or operations shall remain the sole and exclusive property of the Service Provider and Sponsor
shall hold it in the strictest confidence. 
 4.4 Supply of Materials. In the event that Sponsor provides any materials to Service Provider in
connection with the Services (“Materials”), Service Provider agrees that the Materials, no express or implied licenses or other rights relating to the Materials are provided to Service Provider under any patents, patent applications, trade
secrets or other proprietary rights of Sponsor, Service Provider agrees that the Materials shall: (i) only be used as specified in writing by Sponsor and not for any other purpose; (ii) be used in compliance at all times with all
applicable statutes and regulations; and (iii) not be transferred to any third party without the prior written consent of Sponsor. Upon completion of any Project and upon direction of Sponsor, Service Provider shall provide Sponsor
with an accounting, and shall cause the investigator performing a Work Order to maintain records, of all Materials supplied by Sponsor. 
  

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 4.5 Survival of Section 4. The obligations imposed by this Section 4 shall survive the expiration or
earlier termination, for any reason, of this Agreement. 
  

	5.	CONFIDENTIALITY/PUBLICATIONS 

 5.1 Confidential Information. Service
Provider shall not, at any time, without Sponsor’s prior written consent, disclose to any third party any of Sponsor’s Confidential Information or the fact that the Services are being conducted on behalf of Sponsor. Service Provider shall
use such Confidential Information solely for the purposes for which Sponsor provided it. Service Provider shall keep such information secure, secret and confidential and cause its directors, officers, employees, or agents to keep such information
secure, secret and confidential and shall take all reasonable precautions to prevent any unauthorized use or disclosure of the Confidential Information. For purposes of this Agreement, “Confidential Information” means any information of
Sponsor in any form, whether provided by Sponsor or its agent or designee, whether of a technical, business or other nature, including, but not limited to, information, documents, data and images which (i) relate to Sponsor’s trade
secrets, products, promotional material, developments, proprietary rights or business affairs, (ii) relate to or are part of Materials, Sponsor Data or Inventions, (iii) are developed by or compiled by Service Provider pursuant hereto and
relate to the Services, (iv) were exchanged under the Letter Agreement, dated January 16, 2007, or (v) were exchanged by the parties prior to the date hereof. Confidential Information does not include any information that: 

(a) Service Provider can prove (with written documentation) was known to it prior to the date of this Agreement and any other agreement between the
parties hereto; 
 (b) Service Provider can prove was lawfully obtained from a third party without any obligation of confidentiality; or

 (c) is or becomes part of the public domain through no act or violation of any obligation of Service Provider. 
 5.2 Required Disclosure. Notwithstanding anything to the contrary in section 5.1 above: 
 (a) if Service Provider is required by Applicable Law to disclose Confidential Information to a third party, Service Provider shall notify Sponsor, and
Service Provider and Sponsor shall agree to a mutually satisfactory way to disclose such information as necessary and in accordance with Applicable Law; and 
 (b) with respect to research subjects’ medical records, the parties agree to hold in confidence the identity and personal health information of the patients in accordance with Applicable Law. 
 5.3 In the event that Service Provider supplies to Sponsor any of its confidential information (including but not limited to marketing and selling plans, business plans,
budgets and 

  

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unpublished financial statements, licenses, customer lists, supplier lists, Service Provider’s Property), Sponsor shall keep it confidential in the same
manner as Service Provider is required to keep Confidential Information confidential. 
 5.4 Return of Confidential Information. Upon expiration of
this Agreement, completion of a Work Order, earlier termination of a Work Order or this Agreement, or otherwise upon the request of Sponsor, Service Provider will promptly (i) provide a copy of all relevant Confidential Information to Sponsor
in a form acceptable to Sponsor and (ii) to the extent that Sponsor so requests, provide to Sponsor or destroy all other copies of relevant Confidential Information in Service Provider’s possession or under Service Provider’s control,
except that one copy thereof may be retained as otherwise required by Applicable Law or as necessary to demonstrate compliance with the terms hereof. Service Provider will not withhold from Sponsor any Confidential Information as a means of
resolving any dispute. Service Provider will not utilize Confidential Information for any purpose other than that of rendering the Services. 
 5.5
Publications. Service Provider shall have no right to publish any Confidential Information. 
 5.6 Handling and Reconstruction of and Access to
Confidential Information. Service Provider will establish and maintain rigorous safety and facility procedures, data security procedures and other safeguards against the destruction, loss, or alteration of Confidential Information in the
possession of Service Provider. Service Provider will be responsible for developing and maintaining procedures for the recovery and reconstruction of such lost Confidential Information. Service Provider will promptly notify Sponsor (with full
details) of any security compromises or breaches that might affect the security of any such Confidential Information, including the personal information or personal health information of any individual related to the Sponsor. Service Provider will
correct or remedy, at Sponsor’s request and sole discretion and at no charge to Sponsor, any destruction, loss or alteration of any such Confidential Information that occurs while such Confidential Information is under the control or
supervision of Service Provider, its employee or agents (including permitted subcontractors). Upon reasonable request by Sponsor at any time, Service Provider will promptly retrieve, in the format and on media acceptable to Sponsor, any portion of
such Confidential Information reasonably specified by Sponsor. Sponsor will have unrestricted access to, and the right to review and retain the entirety of, all computer or other files containing such Confidential Information. At no time will any of
such files or other materials or information be stored or held in a form or manner not immediately accessible to Sponsor. Service Provider shall not withhold from Sponsor any Confidential Information in order to settle a dispute. 
  

	6.	TERM AND TERMINATION 

 6.1 Term. The term of this Agreement shall
begin on the date first above mentioned and shall end three (3) year(s) thereafter, unless sooner terminated in accordance with the terms hereof. The term of this Agreement may be extended upon written agreement by Sponsor and Service Provider.

  

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 6.2 Termination. 
 (a) A Work Order or this Agreement, and with respect to Sponsor only, Services under a Work Order, may be terminated (i) by Sponsor at any time in the exercise of its sole discretion upon 30 days written notice
to Service Provider, (ii) by a party upon the material breach of this Agreement by the other party, which material breach continues unremedied for thirty (30) days after delivery to the breaching party by the nonbreaching party of notice
of the material breach, (iii) by a party immediately in the event of the bankruptcy (voluntary or otherwise), insolvency or other similar financial distress of the other party, or (iv) by a party or the parties pursuant to
Section 11.13. 
 (b) Upon termination or expiration, Service Provider shall
(i) promptly terminate all relevant Services, provided that Service Provider shall not immediately terminate Services necessary in connection with responsible treatment of any study subjects and (ii) Service Provider will work with Sponsor
to transition the relevant Services to Sponsor or its designee. In the event of a termination by Sponsor pursuant to Section 6.2(a)(ii), 6.2(a)(iii), 6.2(a)(iv) or 6.2(a)(v), the foregoing shall be provided by Service Provider to Sponsor
without charge. In the event of a termination by Sponsor pursuant to Section 6.2(a)(i) or by Service Provider pursuant to Section 6.2(a)(ii) or 6.2(a)(iii), the total sums payable by Sponsor shall be equitably pro-rated for actual Services
completed by the date of such termination in accordance with this Agreement and the relevant Work Order, with any unexpended funds previously paid by Sponsor to Service Provider promptly refunded to Sponsor and any payments future non-cancellable
pass through costs accrued will be promptly paid by Sponsor. In the event of any other termination, the parties shall negotiate in good faith to determine the appropriate amount to be paid by Sponsor to Service Provider (or refunded to Sponsor by
Service Provider, as the case may be), in light of the circumstances of such termination, in compensation for all Services rendered in accordance with this Agreement. Upon the termination or expiration of a Work Order or this Agreement and in
addition to fulfilling the requirements of Section 5.3, Service Provider shall promptly return to Sponsor any unused study supplies, including all unused study drug and placebo. 
  

	7.	AUDIT 

 Sponsor and its agents and designees shall have the
right at anytime upon reasonable notice to audit Service Provider’s facilities, systems, records (financial and otherwise), procedures, and documentation related to this Agreement, as well as the progress of Services and all information and
results derived from or relating to such Services, wherever performed, including, without limitation, at third party premises. Notwithstanding, Sponsor shall not utilize a direct competitor of Service Provider to audit Service Provider’s
financials or other proprietary information of Service Provider absent the prior written consent of Service Provider, such consent not to be unreasonably withheld. In connection with any audit, Service Provider shall also provide Sponsor reasonable
access to its personnel upon reasonable notice. Such audits may be conducted upon reasonable notice during the term of this Agreement and for a period of up to two (2) years after termination or expiration. In connection with a financial audit,
if the audit reveals that payments made by Sponsor to Service Provider for any period audited have not exceeded amounts owed by Sponsor for such period, Sponsor shall pay the costs of such audit and Service Provider shall not have any liability
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audited exceed amounts actually owed by Sponsor for such period, but by less than three percent (3%) of the amount actually owed, Service Provider shall
in addition to repaying any overpaid amounts equally share with Sponsor the reasonable costs of such audit work. If the audit reveals that payments made by Sponsor to Service Provider for any period audited exceed amounts actually owed by Sponsor
for such period by three percent (3%) or more of the amount actually owed, Service Provider shall in addition to repaying any overpaid amounts pay the reasonable costs of such audit work. In no event shall Sponsor be liable to pay Service
Provider’s costs and expenses related to this Section. 
  

	8.	ADVERSE EVENTS 

 To the extent appropriate with respect to
Services to be delivered in connection with a given Work Order, Service Provider shall have a system to collect all serious adverse events, which shall include instructing investigators to notify Service Provider and/or Sponsor directly and
immediately, but in no even later than within one business day of a serious adverse event (expected or unexpected). Service Provider will notify Sponsor by email and/or by fax, but in no event later than within one business day of its own receipt of
notice of any serious adverse event. Service Provider will promptly thereafter follow-up with written documentation to Sponsor. Service Provider shall notify all study sites and investigators of any serious, unexpected adverse event as required by
Applicable Law within legally pre-specified timeframes, unless Sponsor agrees to take such responsibility. Non serious adverse events will be captured by Service Provider in case report forms during the course of the Study. 
  

	9.	INDEMNIFICATION 

 9.1 Indemnification by Sponsor. Sponsor shall indemnify, defend and hold harmless Service Provider and its directors, officers, employees, subcontractors and agents (the “Service Provider Indemnitees”) against any and all
losses, costs, expenses and damages, including but not limited to reasonable attorneys’ fees, resulting from a third party claim in respect of (i) the negligence or willful misconduct of Sponsor, (ii) a material breach of this
Agreement by Sponsor, or (iii) the personal injury caused by the use of a study drug supplied by Sponsor in connection with a Work Order or Project, except to the extent that any such claim is caused by a Service Provider Indemnitee’s
negligence, malpractice, reckless or intentional misconduct, or breach of this Agreement. Sponsor shall have the right, at its sole option, to defend against such claim including selection of counsel and control of the proceedings, including
reasonable settlement. Each Service Provider Indemnitee shall fully cooperate and aid in such defense. Service Provider shall have the right to select and to obtain representation by separate legal counsel at its own expense. Notwithstanding
anything to the contrary herein, Sponsor shall have the right to select counsel for, direct and control any proceedings related to any of its study drugs at the reasonable expense of the indemnifying party, subject to Service Provider’s
approval, not unreasonably withheld, conditioned, or delayed. 
 9.2 Indemnification by Service Provider. Service Provider shall indemnify, defend and
hold harmless Sponsor and its affiliates and its and their respective directors, officers, employees and agents against (the “Sponsor Indemnitees”) any and all losses, costs, expenses and damages, including but not limited to reasonable
attorneys’ fees, arising from a third party claim resulting 

  

 12 

 
from the (i) material breach of this Agreement by Service Provider, including but not limited to adherence to an applicable protocol, Applicable Law or
any reasonable written instructions or other directions given by Sponsor or (ii) the negligence or intentional misconduct of any Service Provider Indemnitee, except to the extent that such claim is caused by a Sponsor Indemnitee’s
negligence or malpractice, reckless or intentional misconduct, or breach of this Agreement. Subject to the final sentence of Section 9.1. Service Provider shall have the right to defend against such claim, including selection of counsel and
control of the proceedings, including reasonable settlement. Each Sponsor Indemnitee shall fully cooperate and aid in such defense. Sponsor shall have the right to select and to obtain representation by separate legal counsel at its own expense.

 9.3 Limitations of Liabilities. 
 (a)
Neither party shall be liable to the other for loss, damage, or liability in respect of loss of profits, business or revenue loss, special, indirect or consequential loss (even if foreseeable or in the contemplation of either party). 
 (b) Each party shall not be responsible for a failure to meet its obligations under this Agreement to the extent caused by the following:
(i) materially inaccurate data provided by the other party; (ii) any failure of the other party to meet its obligations stated in this Agreement; (iii) any failure of equipment, facilities or services not controlled or supplied by
such party. It is understood that a party shall not be liable for the other party’s delays. 
  

	10.	CONTRACTING/SUBCONTRACTING 

 All services or materials for
which Service Provider contracts, subcontracts or purchases for purposes of this Agreement shall be subject to prior written approval by Sponsor. Service Provider agrees to provide to Sponsor a copy of any such contract for services or materials
prior to execution for comment, in particular regarding costs, source, payment schedule, early termination penalties, confidentiality and patent rights. Where Service Provider has selected, contracted with, or supervises subcontractors for Services,
it shall be responsible for managing any such permitted subcontractors hereunder. Service Provider hereby unconditionally guarantees the performance of Services and delivery of Deliverables in accordance with this Agreement by any such permitted
subcontractor hereunder. In the event that Sponsor insists Service Provider contract with a subcontractor against the written advice of Service Provider, Sponsor shall be responsible for the performance of such subcontractor and Service Provider
shall not. 
  

	11.	MISCELLANEOUS 

 11.1 Entire Agreement. This Agreement constitutes
the entire agreement between the parties and supersedes all prior negotiations, representations or agreements, either written or oral, with respect to the subject matter hereof. 
 11.2 Obligation of Investigators. All investigators and other personnel involved in the conduct of the Services will be informed by Service Provider of all of the relevant provisions of this Agreement and the
obligations of Service Provider and will be required by Service Provider to comply therewith. 
  

 13 

 11.3 Publicity. None of the parties shall use the name of any other party for promotional purposes without the
prior written consent of the party whose name is proposed to be used, nor shall either party disclose the existence or substance of this Agreement except as required by Applicable Law. Notwithstanding the preceding, the participation of Service
Provider in the matters undertaken pursuant to this Agreement may be recognized by Sponsor in publications and promotional materials that may result from the Services. 
 11.4 Governing Law. The laws of the State of Delaware shall govern this Agreement. 
 11.5 Independent
Contractor. Service Provider, investigators recruited by Service Provider, and research staff at study sites recruited by Service Provider are acting in the capacity of independent contractors hereunder and not as employees of Sponsor.

 11.6 Agreement Modification/Assignment. This Agreement, or any of its Exhibits, may not be altered, amended, or modified except by a written
document signed by the parties hereto. Service Provider will not assign this Agreement or any of its rights or obligations without the prior written consent of Sponsor and any purported assignment in contravention of this Section shall be null and
void; provided, however, that Sponsor may assign this Agreement in connection with (i) the sale, transfer or other disposition of its assets related to this Agreement, (ii) a change in control of Sponsor or (iii) the sale or transfer
of substantially all of Sponsor’s outstanding stock. 
 11.7 Notice. Any notices given hereunder shall be sent by fax or email, with a
confirmation copy sent via overnight courier or via overnight courier to the following addresses (or such other address as a party may designate as a notice address in a prior written notice to the other party) and shall be deemed delivered when
received (or if received on a weekend or holiday, on the next business day thereafter) as follows: 
  

			
	If to Sponsor:	 	Neurobiological Technologies, Inc.
		 	2000 Powell Street
		 	Suite 800
		 	Emeryville, CA 94608
		 	Attention: Cheryl D. Swanson, Contracts Administration
		 	Telephone: 510-595-6000
		 	Fax: 510-595-6006
		 	Email: cswanson@ntii.com
		
	With a copy to:	 	Heller Ehrman LLP
		 	7 Times Square
		 	New York, New York 10036
		 	Attention: Blaine Templeman
		 	Telephone: (212) 847-8572
		 	Fax: (212) 763-7600
		 	Email: blaine.templeman@hellerehrman.com

  

 14 

			
	 If to Service Provider:
	 	ICON Clinical Research Limited
		 	South County Business Park, Leopardstown
		 	Dublin, Ireland
		 	Attention: Legal Affairs
		 	Telephone: 00-353-1-2912000
		 	Fax: 00-353-1-2912700 (Generic)
		 	        00-353-1-2912737 (Commercial Affairs)
		 	Email: commercialaffairsirl@iconirl.com

 11.8 Counterparts. This Agreement may be executed in counterparts, each of which will be deemed an original
and both of which together will constitute one and the same instrument. 
 11.9 Survival of Obligations. Notwithstanding expiration or termination of
this Agreement for any reason, rights and obligations, which by their nature should survive, will remain in full force and effect. In particular Sections 1.5, 1.6, 2.4, 2.8, 2.10, 2.11, 2.12, 2.13, 2.14, 2.15, 2.16, 3, 4, 5, 6.2(b), 7, 9, 11.4,
11.7, 11.9, 11.12, 11.14, and 11.15 will survive the expiration or termination of this Agreement. 
 11.10 Enforceability. If any of the provisions or
a portion of any provision of this Agreement is held to be unenforceable or invalid by a court of competent jurisdiction, the validity and enforceability of the enforceable portion of any such provision and/or the remaining provisions will not be
affected thereby. 
 11.11 Conflict of Interest. During the course of providing Services, Service Provider shall not undertake to provide services for
any person or organization that conflicts with, hinders, delays and adversely impacts the execution of Services and its obligations hereunder. 
 11.12
Insurance. Service Provider and Sponsor shall at their own expense obtain and maintain insurance in amounts and coverages that are commensurate with industry standards for, with respect to Sponsor, studies substantially similar to the Study
and, with respect to Service Provider, for performance of services substantially similar to the Services. Each party will, forthwith on request by the other, provide the party requesting the same with evidence of the insurance as that party may
reasonably require. 
 11.13 Force Majeure. If either party shall be delayed or hindered in or prevented from the performance of any act required
hereunder by reason of strike, lockouts, labor troubles, restrictive governmental or judicial orders or decrees, riots, insurrection, war, acts of God, inclement weather or other reason or cause reasonably beyond such party’s control (each a
“Disability”), then performance of such act shall be excused for the period of such Disability. The party incurring the Disability shall provide notice to the other of the commencement and termination of the Disability. Should a Disability
continue for more than three (3) months, the party unaffected by the Disability may terminate this Agreement upon prior written notice to the affected party. Should the Disability equally affect the performance of both parties, then such
termination shall only be by mutual written agreement. 
  

 15 

 11.14 Third Party Beneficiaries. The provisions set forth in this Agreement are for the sole benefit of the
parties hereto and their successors and assigns, and they shall not be construed as conferring any rights on any other persons. 
 11.15 Material Inside
Information. Information that any agent or employee of Service Provider may learn during the course of performing this Agreement, including Confidential Information, may be deemed to be “material inside information” about Sponsor. In
order to avoid any actual or perceived conflicts of interest, Service Provider will not purchase or trade in any stock or other securities of Sponsor, or recommend that others do so, during the term of the Study. This restriction shall also apply to
all Service Provider employees involved in the Services, and Service provider shall communicate this restriction to all such employees. Notwithstanding the foregoing, this Section shall not restrict in any way Service Provider or its employees and
agents from making investments in pooled investment vehicles such as mutual funds, or in individual securities, in the ordinary course of business. 
 11.16
Staff Solicitation. During the term of any Work Order hereunder and for six (6) months thereafter, each party agrees not to solicit directly, any employee of the other party for employment, whether as an employee, independent contractor
or otherwise, if such person devoted substantial efforts to the completion of the Services under the relevant Work Order. This provision shall not apply to persons who apply for a position with a party and are hired by the party, ex-employees of the
party, or responses of potential employees to general solicitations. 
  

 16 

 IN WITNESS WHEREOF, the parties hereto have caused this Master Clinical Services Agreement to be executed
by their duly authorized representatives as of the date first above written. 
  

			
	NEUROBIOLOGICAL TECHNOLOGIES, INC.
		
	BY:	 	 /s/ Craig W. Carlson

	Name:	 	
	Title:	 	
	
	ICON CLINICAL RESEARCH LIMITED
		
	BY:	 	 /s/ Sean Leech

	Name:	 	Sean Leech
	Title:	 	Executive VP Commercial and Organizational Development

  

 17 
 Confidential 

 EXHIBIT A 
 FORM OF WORK ORDER 
 [Study Name] 
 [Protocol No.] 
 Pursuant to Section 1.2 of the Master Clinical Services
Agreement dated January 16, 2007, by and between Sponsor and Service Provider and in consideration of the mutual promises contained therein and for other good and valuable consideration the receipt and adequacy of which each of the parties does
hereby acknowledge, the parties hereby agree to amend Exhibit B by adding the attached new Work Order entitled
                                        ,
which is designated Work Order B-        . This Work Order B-         is effective as of
                    , 200    . 
 Transfer of Obligations. Pursuant to 21 CFR §312.52, Neurobiological Technologies, Inc., as sponsor of the Study, hereby transfers to Service Provider and Service Provider hereby assumes all the obligations of
Sponsor for the Services set forth in Attachment A and included on Form FDA 1571, Section 13. Sponsor shall retain the right to assume any of the duties delegated to Service Provider at any time and the Services and Attachments A and B shall be
adjusted accordingly. 
 If an Affiliate of Service Provider is executing this Work Order, then Affiliate agrees to adhere to all the terms
and conditions of this Agreement as if such Affiliate were Service Provider. 
 Work Order
B-         contains the following Attachments, each of which is made a part hereof: 
  

					
	Attachment A	 	–	 	Description of Services/Specifications/Description of Deliverables and Intended Use of Deliverables/Transfer of Obligations
	Attachment B	 	–	 	Budgets, Fees, Pass-through Costs, and Payment Schedule
	Attachment C	 	–	 	Materials Provided by Either Party
	Attachment D	 	–	 	Project Schedule
	Attachment E	 	–	 	Core Team Members
	Attachment F	 	–	 	Protocol or Protocol Summary
	Attachment G	 	–	 	Reports and Information Management/Regular Meetings
	Attachment H	 	–	 	Special Insurance

									
	NEUROBIOLOGICAL TECHNOLOGIES, INC.	 		 	[SERVICE PROVIDER]
					
	By:	 	  
	 		 	By:	 	  

					
	Name:	 	  
	 		 	Name:	 	  

					
	Title:	 	  
	 		 	Title:	 	  

					
	Date:	 	  
	 		 	Date:	 	  

  

					
	 Acknowledged and Agreed:
	 	
		
	  
	 	
		
	                                      
                                        
  , Project Manager	 	

 EXHIBIT B 
 WORK ORDERS 
 (in the form of Exhibit A) 

 EXHIBIT C 
 The following provisions shall also apply with respect to Services to be performed by ICON CENTRAL LABORATORIES, INC. (hereinafter referred to as “Service Provider Lab”): 
 1. Fees – SPONSOR shall pay the fees set forth in the applicable lab proposal attached to the Work Order (or any Exhibit thereto) in consideration of Service
Provider Lab providing the Services set forth therein. 
 2. Service Mechanics 
 (a) Service Provider Lab shall use reasonable best efforts to ensure that consistent test methodologies and reference ranges are used at all times during
the provision of the lab services. In the event that any test kit or any other equipment or substance used by Service Provider Lab in the provision of the lab services becomes unsuitable or unavailable (e.g. product discontinuation or FDA mandate),
Service Provider Lab may adopt methodologies and reference ranges of any alternative test kits or equipment or substance which are approved by the Sponsor. The parties agree that all tests kits shipped under this Agreement shall remain Service
Provider Lab’s property until paid for by SPONSOR in accordance with the terms of this Attachment B and the applicable lab proposal. In the event any test kits are shipped, but not used, SPONSOR shall be responsible for proper disposal of such
test kits in accordance with Applicable Law. 
 (b) IATA The parties acknowledge to each other that the shippers of all infectious materials
under this Agreement are required to be certified under the pertinent regulations of the International Air Transport Association (“IATA”) relating to the handling and transportation of infectious materials and that the shippers
(investigator sites) are responsible to comply with all pertinent IATA regulations. 
 3. Investigator Meetings SPONSOR may require a representative
from Service Provider Lab to attend all investigator meetings, and such representative from Service Provider Lab shall attend such meetings for the purpose of training the representatives of SPONSOR and any third parties in connection with the
provision of the lab services at SPONSOR’s cost and expense, which will be agreed by the parties in advance. 
 4. Records Service
Provider Lab shall maintain relevant data records pertaining to the lab services performed as outlined in Service Provider Lab quality system documents for a period required by Applicable Law. Such records shall be maintained in a proper and ordered
manner in accordance with Applicable Law. SPONSOR shall be entitled to obtain copies of any of the Records at any time maintained by Service Provider Lab. After the required maintenance requirements under Applicable Law have expired, Service
Provider Lab may give notice to SPONSOR requesting that SPONSOR specify whether it requires Service Provider Lab to continue to maintain such records or whether such records should be destroyed. In the event that SPONSOR requires that such records
be destroyed it shall reimburse Service Provider Lab the reasonable costs and expenses of destroying such records. In the event that SPONSOR requires that Service Provider Lab continue to maintain such records, SPONSOR shall reimburse Service
Provider Lab its reasonable costs and expenses for maintaining such records.Executive Termination Agreement with Jean-Paul Mangeolle

 Exhibit 10.1 
 EXECUTIVE TERMINATION AGREEMENT, dated as of September 10, 2007 (the “Effective Date”), between MILLIPORE CORPORATION, a
Massachusetts corporation with offices at 290 Concord Road, Billerica, Massachusetts 01821 (the “Company”), and Jean-Paul Mangeolle (the “Executive”). 
 WHEREAS the Executive is an officer and key member of the Company’s management; 
 WHEREAS the Company
believes that it is in its best interests, as well as those of its stockholders, to assure the continuity of management in general and the Executive in particular, for a fixed period of time in the event of an actual or threatened change of control
of the Company and whether or not such change of control is determined by the Board of Directors of the Company (the “Board”) to be in the best interest of its stockholders; 
 WHEREAS this Agreement is not intended to alter materially the compensation, benefits or terms of employment that the Executive could reasonably expect
in the absence of a change in control of the Company, but is intended to encourage and reward the Executive’s compliance with the wishes of the Board whatever they may be in the event that a change of control occurs or is threatened; and

 WHEREAS this Agreement supersedes and replaces the previous the Executive Termination Agreement between the Executive and the Company
dated January 9, 2006. 
 NOW, THEREFORE, in consideration of the mutual agreements, provisions and covenants contained herein, and
intending to be legally bound hereby, the parties hereto agree as follows: 
 ARTICLE I 
 Term of this Agreement; Defined Terms. 
 SECTION 1.01. The term of this Agreement (such term as it may be extended is herein referred to as the “Term”) shall be for a period commencing on the date first written above and ending on March 1, 2011, provided that the
Term may be extended by action of the Committee effective as of each March 1st beginning in 2009 as part of its annual compensation review so that the then remaining Term is three years. Notwithstanding any such notice, the Term shall not
expire before the second anniversary of a Change of Control that occurs prior to expiration of the Term. Definitions of capitalized terms used in this Agreement are provided in Exhibit A to this Agreement. 
 ARTICLE II 
 The Company’s
Covenants Summarized 
 SECTION 2.01. In order to induce the Executive to remain in the employ of the Company and in consideration of
the Executive’s covenants set forth in Article III, the Company agrees, under the conditions described herein, to provide the Executive with the payments and 

  

 -1- 

 
benefits described in this Agreement in the event the Executive’s employment with the Company is terminated following a Change of Control. No amount or
benefit shall be payable under this Agreement unless there shall have been (or, under the terms hereof, there shall be deemed to have been) a termination of the Executive’s employment with the Company following a Change of Control. 

ARTICLE III 
 The
Executive’s Employment Obligations 
 SECTION 3.01. If an Impending Change of Control should occur while the Executive is
employed by the Company, the Executive agrees to remain in the employ of the Company for at least the Period of Employment in the position and with the duties and responsibilities in effect immediately prior to the Impending Change of Control, with
such changes therein as may from time to time be made by the Board and upon the other terms and conditions hereinafter stated, provided that the foregoing shall not prevent the Executive from terminating the Executive’s employment for Good
Reason. 
 SECTION 3.02. The Executive agrees that during the Period of Employment and prior to any Change of Control, subject to the
Executive’s fiduciary duties to the Company and its stockholders, the Executive will exercise the Executive’s best efforts to bring about whatever result the Board determines to be in the best interests of the Company and its stockholders
relative to any Impending Change of Control, (i.e., to help resist any such Change of Control if the Board determines that to be in the best interests of the Company and its stockholders, and to bring about such Change of Control if the Board
determines that to be the preferable alternative). The Executive agrees to use the Executive’s best efforts at and after the occurrence of a Change of Control to effect an orderly and beneficial transfer of control to the party or parties
comprising the new control group. 
 SECTION 3.03. Nothing in this Agreement shall be deemed to prevent the Executive from remaining in the
employ of the Company or any successor beyond the Period of Employment either on the terms and conditions set forth herein or on others that may be mutually agreed upon. 
 ARTICLE IV 
 Compensation Other Than Severance Payments 
 SECTION 4.01. Following a Change of Control, during any period that the Executive fails to perform the Executive’s full-time duties with the Company
as a result of Disability, the Executive shall be compensated as provided pursuant to the terms of the Company’s short- and long-term disability plans as in effect as of immediately prior to a Change of Control or, if more favorable, as of any
time thereafter, together with all other compensation and benefits payable to the Executive pursuant to the terms of any compensation or benefit plan, program or arrangement maintained by the Company during such period. 
 SECTION 4.02. If the Executive’s employment shall be terminated for any reason following a Change of Control, the Company shall pay the
Executive’s full salary to the 

  

 -2- 

 
Executive through the Date of Termination at the rate in effect at the time the Notice of Termination is given, together with all other compensation and
benefits payable to the Executive through the Date of Termination (including, without limitation, all incentive compensation amounts owed the Executive for a completed calendar year to the extent not yet then paid but excluding any annual bonus for
the year in which the Date of Termination occurs unless specifically provided for in Section 5.03 of this Agreement) under the terms of any compensation or benefit plan, program or arrangement maintained by the Company during such period.

 SECTION 4.03. If the Executive’s employment shall be terminated for any reason following a Change of Control, the Company shall pay
the Executive, subject to Section 5.01, such normal post-termination compensation and benefits as may be provided by the Company’s retirement, insurance and other compensation or benefit plans, programs and arrangements, as in effect as of
immediately prior to a Change of Control or, if more favorable, as of any time thereafter. 
 ARTICLE V 
 Severance Payments 
 SECTION
5.01. In lieu of any other severance compensation or benefits to which the Executive may otherwise be entitled under any plan, program, policy or arrangement of the Company, the Severance Agreement or any other agreement between the Executive and
the Company (which compensation and benefits the Executive hereby expressly waives to the extent the Executive receives the compensation and benefits provided for hereunder), the Company shall pay the Executive, in addition to the payments and
benefits described in Article IV, the payments described in this Article V (the “Severance Payments”) upon the termination of the Executive’s employment within two years following a Change of Control, unless such termination is
(a) by the Company for Cause or due to the Executive’s Disability, (b) by reason of the Executive’s death, or (c) by the Executive without Good Reason. The Executive’s employment shall be deemed to have been terminated
following a Change of Control by the Company without Cause or by the Executive with Good Reason if (i) the Executive is requested by the Company to terminate the Executive’s employment after a Change of Control, (ii) the
Executive’s employment is terminated prior to a Change of Control without Cause at the direction of a person or entity who has entered into an agreement with the Company the consummation of which will constitute a Change of Control or
(iii) if the Executive terminates the Executive’s employment prior to a Change of Control with Good Reason (determined by treating an Impending Change of Control as a Change of Control in applying the definition of Good Reason) if the
circumstance or event which constitutes Good Reason occurs at the direction of such person or entity. Any termination of Executive’s employment in respect of which the Executive is entitled to Severance Payments is referred to as a
“Qualifying Termination”. 
 SECTION 5.02. In the event of a Qualifying Termination, the Company shall provide the Executive with a
lump sum severance payment in an amount equal to two times the sum of (a) the Executive’s then current base salary (without regard to any reduction that gave rise to Good Reason) plus (b) the greater of (i) the average bonus
earned by the Executive in respect of the three most recently completed calendar years prior to the Qualifying Termination and (ii) the Executive’s target annual bonus (without regard to any reduction that gave rise to Good Reason) for the
year in which the Qualifying Termination occurs six months and a day after a Qualifying Termination. 
  

 -3- 

 SECTION 5.03. In the event of a Qualifying Termination, the Company shall pay the Executive a lump sum
cash amount equal to the Executive’s target annual bonus (without regard to any reduction that gave rise to Good Reason) for the year in which the Qualifying Termination occurs, multiplied by a fraction, the numerator of which is the number of
days elapsed in such year through the date of termination, and the denominator of which is 365, payable six months and a day following the Qualifying Termination. 
 SECTION 5.04. In the event of a Qualifying Termination, the Executive and the Executive’s family shall receive continued provision of the Company’s standard group employee insurance coverages (e.g. health,
dental, disability, and life), as elected by the Executive and as in effect as of immediately prior to a Change of Control or, if more favorable, as of any time thereafter, for a period (the “Company-Paid Coverage Period”) that commences
upon the Qualifying Termination and ends upon the earlier of (i) the expiration of two years thereafter, or (ii) the date that the Executive becomes covered under another employer’s group health, dental, disability or life insurance
plans that provide the Executive with benefits not less favorable than those being provided to the Executive and the Executive’s family members as of immediately prior to a Change of Control or, if more favorable, as of any time thereafter;
provided, however, that if the continuation of any or all of such insurance coverages are not permitted under the terms of the Company’s group insurance plans, the Company shall arrange for the provision of substantially
equivalent insurance coverages to be provided under alternative plans or arrangements that provide such coverages on substantially the same terms and at a cost to the Executive that is not greater than that incurred by the Executive (determined on
an after-tax basis) immediately prior to a Change of Control or, if more favorable, at any time thereafter. Notwithstanding the foregoing, in the event any such coverage is unavailable or otherwise commercially impracticable, the Company may (but is
not required to) satisfy its obligation under this Section 3.01(b) by paying to the Executive the cost of such coverage if it were available, as determined in good faith by the Company. For purposes of Title X of the Consolidated Budget
Reconciliation Act of 1985 (“COBRA”), the date of the “qualifying event” for the Executive and the Executive’s family members shall be the date of the Executive’s employment termination; provided, however, that such
date shall be the date on which the Executive loses coverage if the applicable group health plan provides for such treatment. To the extent any medical, dental, prescription drug, or other health benefits (collectively, the “Medical
Benefits”) that may be required to be provided by the Company during the Company-Paid Coverage Period that are provided under a so-called “self-insured” benefit plan which is subject to Section 105(h) of the Code shall be
structured so that on or about the first day of each month for which coverage is to be provided the Company shall pay to the Executive an amount in cash sufficient (taking into account applicable taxes) to cover the applicable premium for the
Medical Benefits coverage for that month. The Executive’s premium payments to the Company for Medical Benefits shall be due on the last day of the month to which the coverage relates. The parties intend that the first 18 months of Medical
Benefits coverage shall be exempt from the application of Section 409A, and that any remaining payments by the Company for Medical Benefits shall be considered in compliance with Section 409A. 
  

 -4- 

 ARTICLE VI 
 Treatment of Stock Awards on and after a Change of Control 
 SECTION 6.01. The vesting of the
Executive’s Stock Awards shall be accelerated solely by reason of a Change of Control only if the surviving corporation or acquiring corporation following a Change of Control refuses to assume or continue the Executive’s Stock Awards or to
substitute similar Stock Awards for those outstanding immediately prior to the Change of Control. If the Executive’s Stock Awards are so continued, assumed or substituted and at any time after the Change of Control the Executive’s
employment is terminated by the Company without Cause or the Executive for Good Reason, then the vesting and exercisability of all unvested Stock Awards held by the Executive shall be accelerated in full and any reacquisition rights held by the
Company with respect to a Stock Award shall lapse in full, in each case, upon such termination. By signing this Agreement, the Executive waives any greater rights to accelerated vesting with respect to the Stock Awards that the Executive may
currently have under any plan, agreement, arrangement or policy (written or unwritten) with the Company or any of its subsidiaries or affiliates, and agrees to cooperate with the Company in executing amendments or consents to further the intent and
purposes of this Section 6.01. Enforcement of the terms of this Section 6.01 shall survive termination of this Executive Termination Agreement. 
 ARTICLE VII 
 Conditions to Severance Benefits and Accelerated Vesting of Stock Awards 

 SECTION 7.01. The Executive’s entitlement to receive the Severance Payments and accelerated vesting of Stock Awards under
Section 6.01 due to a Qualifying Termination shall be conditioned upon the Executive having complied to the best of the Executive’s abilities with the commitments contained in Sections 3.01 and 3.02 and the conditions set forth in
Section 7.02. In the event of a Qualifying Termination, the Executive shall be deemed to have so complied if the Executive shall have complied to the best of the Executive’s abilities with the requirements of those Sections until the time
of the Executive’s discharge or resignation. 
 SECTION 7.02. Conditions. Severance Payments and accelerated vesting of Stock
Awards under Section 6.01 are subject to the Executive’s: 
 (a) compliance with the provisions of Article IX hereof
and Article V of the Severance Agreement; 
 (b) delivery to the Company of an executed Agreement and General Release (the
“General Release”), which shall be executed substantially in the form attached hereto as Exhibit B (with such changes therein or additions thereto as needed under then applicable law to give effect to its intent and purpose) within 21 days
of presentation thereof by the Company to the Executive; and 
 (c) delivery to the Company of a resignation from all offices,
directorships and fiduciary positions with the Company, its affiliates and employee benefit plans. 
  

 -5- 

 SECTION 7.03. If the Executive fails to materially comply with any obligation or covenant under
Section 5.02 of the Severance Agreement or is subsequently determined to have terminated employment for Cause under Section 11.02 below, the Company’s obligations to make any additional payments or provide any additional benefits or
other rights or entitlements to Executive pursuant to any provision of this Agreement shall immediately cease and Executive shall be required to immediately repay to the Company all amounts theretofore paid or otherwise provided to Executive
pursuant to Sections 5.02 and 5.03 of this Executive Termination Agreement. The Company may recover amounts under this Section 7.03 by set-off from any amounts otherwise due to Executive under any other plan, program or arrangement if the
Executive fails to make any required repayment within 15 business days after written demand to the Executive. 
 ARTICLE VIII

 Section 4999 Excise Tax 
 SECTION 8.01. If any payments, rights or benefits (whether pursuant to the terms of this Executive Termination Agreement or any other plan, arrangement or agreement of Executive with the Company or with any person
affiliated with the Company and whether or not the Executive’s employment has then terminated (the “Payments”)) received or to be received by Executive will be subject to the tax (the “Excise Tax”) imposed by
Section 4999 of the Code (or any similar tax that may hereafter be imposed), then the Company shall pay to Executive an amount in addition to the Payments (the “Gross-Up Payment”) as calculated below. The Gross Up Payment shall be in
an amount such that, after deduction of any Excise Tax on the Payments and any federal, state and local income and employment tax and Excise Tax on the Gross Up Payment, but before deduction for any federal, state or local income and employment tax
on the Payments, the net amount retained by the Executive shall be equal to the Payments. 
 SECTION 8.02. The process for calculating the
Excise Tax, determining the amount of any Gross-Up Payment and other procedures relating to this Article VIII are set forth in Exhibit C attached hereto. For purposes of making the determinations and calculations required herein, the Consultant may
rely on reasonable, good faith interpretations concerning the application of Section 280G and 4999 of the Code, provided that the Consultant shall make such determinations and calculations on the basis of “substantial
authority” (within the meaning of Section 6662 of the Code) and shall provide opinions to that effect to both the Company and Executive. 
 ARTICLE IX 
 Post-Employment Obligations 
 SECTION 9.01. As an inducement to the Company to provide the payments and benefits to the Executive hereunder, the Executive acknowledges and agrees that
in the event that the Executive’s employment is terminated by reason of a Qualifying Termination, the Executive shall be subject to the provisions set forth in Article V of the Severance Agreement, in the same manner as if his employment had
terminated prior to a Change of Control and Executive had received severance benefits under such Severance Agreement. For avoidance of doubt, this Article IX shall survive termination of this Executive Termination Agreement. 
  

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 ARTICLE X 
 Successors; Binding Agreement 
 SECTION 10.01. In addition to any obligations imposed by law
upon any successor to the Company, the Company will require any successor (whether direct or indirect, by purchase, merger, consolidation or otherwise) to all or substantially all of the business and/or assets of the Company to expressly assume and
agree to perform this Executive Termination Agreement in the same manner and to the same extent that the Company would be required to perform it if no such succession had taken place. Failure of the Company to obtain such assumption and agreement
prior to the effectiveness of any such succession shall be a breach of this Executive Termination Agreement and shall entitle the Executive to compensation from the Company in the same amount and on the same terms as the Executive would be entitled
to hereunder if the Executive were to terminate the Executive’s employment for Good Reason after a Change of Control, except that, for purposes of implementing the foregoing, the date on which any such succession becomes effective shall be
deemed the Date of Termination. 
 SECTION 10.02. This Executive Termination Agreement shall inure to the benefit of and be enforceable by
the Executive’s personal or legal representatives, executors, administrators, successors, heirs, distributees, devisees and legatees. If the Executive shall die while any amount would still be payable to the Executive hereunder (other than
amounts which, by their terms, terminate upon the death of the Executive) if the Executive had continued to live, all such amounts, unless otherwise provided herein, shall be paid in accordance with the terms of this Agreement to the executors,
personal representatives or administrators of the Executive’s estate. 
 ARTICLE XI 
 Termination Procedures 
 SECTION 11.01. Notice of Termination. After a Change of Control, any purported termination of the Executive’s employment (other than by reason of death) shall be communicated by written Notice of Termination from one party
hereto to the other party hereto in accordance with Article XI hereof. 
 SECTION 11.02. Termination of Employment for Cause. Any
termination of employment for Cause shall be made by written notice setting forth in detail all acts or omissions upon which the Board is relying for such termination. 
 SECTION 11.03. Dispute Concerning Termination. If the party receiving the Notice of Termination notifies the other party within thirty (30) days after the date such Notice of Termination is given that a
dispute exists concerning the termination, the Date of Termination shall be the date on which the dispute is finally resolved, either by mutual written agreement of the parties or by a final judgment, order or decree of a court of competent
jurisdiction (which is not appealable or with respect to which the time for appeal therefrom has expired and no appeal has been perfected); provided, however, that the Date of Termination shall be extended by a notice of dispute only
if such notice is given in good faith and the party giving such notice pursues the resolution of such dispute with reasonable diligence. The Company shall continue to 

  

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pay the Executive the Executive’s full compensation in effect when the notice giving rise to the dispute was given and continue the Executive as a
participant in all compensation, benefit and insurance plans in which the Executive participated when the Notice of Termination was given (without regard to any reductions that gave rise to Good Reason) until the dispute is finally resolved in
accordance with this Section. Amounts paid under this Section are in addition to all other amounts due under this Agreement and shall not be offset against or reduce any other amounts due under this Agreement. In addition, for purposes of
determining whether any Qualifying Termination has occurred, the date a Notice of Termination is given pursuant to this Section shall be deemed the date of the Executive’s Qualifying Termination. 
 ARTICLE XII 
 Notices 

 SECTION 12.01. For the purpose of this Agreement, notices and all other communications provided for in this Agreement shall be in writing
and shall be deemed to have been duly given (a) on the date of delivery if delivered by hand, (b) on the date of transmission, if delivered by confirmed facsimile, (c) on the first business day following the date of deposit if
delivered by guaranteed overnight delivery service, or (d) on the fourth business day following the date delivered or mailed by United States registered or certified mail, return receipt requested, postage prepaid, addressed as follows:

 If to the Executive: at the address (or to the facsimile number) shown on the records of the Company. 
 To the Company: 
 Millipore Corporation

 290 Concord Road 
 Billerica,
MA 01821 
 Attention: Clerk 
 or to such other
address as either party may have furnished to the other in writing in accordance herewith, except that notices of change of address shall be effective only upon receipt. 
 ARTICLE XIII 
 Legal Fees and Expenses 
 SECTION 13.01. The Company also shall pay to the Executive all legal fees and expenses incurred by the Executive in good faith as a result of a
termination of employment which entitles the Executive to the Severance Payments (including all such fees and expenses, if any, incurred in disputing any such termination) or in seeking in good faith to obtain or enforce any benefit or right
provided by this Agreement or in connection with any tax audit or proceeding to the extent attributable to the application of Section 4999 of the Code to any payment or benefit provided hereunder. Such payments shall be made within five
business days after delivery of the Executive’s written requests for payment accompanied with such evidence of fees and expenses incurred as the Company reasonably may require. 
  

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 ARTICLE XIV 
 No Mitigation and No Offset 
 SECTION 14.01. The amounts payable to the Executive hereunder
shall be absolutely owing, and not subject to reduction or mitigation as a result of employment by the Executive elsewhere after the Executive’s employment with the Company is terminated. 
 SECTION 14.02. There shall be no right of set-off or counterclaim in respect of any claim, debt or obligation against any payments to the Executive, the
Executive’s dependents, beneficiaries or estate, provided for in this Agreement. 
 ARTICLE XV 
 Amendment or Modification; Waiver 
 SECTION 15.01. No provision of this Agreement may be amended, modified or waived unless such amendment, modification or waiver shall be authorized by the Board or any authorized committee of the Board and shall be agreed to in writing,
signed by the Executive and by an officer of the Company thereunto duly authorized; provided, however, that either the Board or the Committee may amend this Agreement at any time as necessary to comply with applicable laws and
regulations without the Executive’s written consent prior to a Change of Control; provided, further, however, that (1) the Company’s unilateral power to amend this Agreement shall be limited to technical,
ministerial, and regulatory requirements generally applicable to all public company officers, and (2) no such amendment would constitute Good Reason as presently defined by this Agreement. Except as otherwise specifically provided in this
Agreement, no waiver by either party hereto of any breach by the other party hereto of any condition or provision of this Agreement to be performed by such other party shall be deemed a waiver of a subsequent breach of such condition or provision or
a waiver of a similar or dissimilar provision or condition at the same time or at any prior or subsequent time. 
 ARTICLE XVI

 Governing Law; Submission to Jurisdiction 
 SECTION 16.01. The validity, interpretation, construction performance and enforcement of this Agreement shall be governed by the laws of the Commonwealth of Massachusetts without giving effect to the principles of
conflict of laws thereof. 
 SECTION 16.02. (a) Except as otherwise specifically provided herein, the Executive and the Company each
hereby irrevocably submits to the exclusive jurisdiction of federal and state courts in the Commonwealth of Massachusetts with respect to any disputes or controversies arising out of or relating to this Agreement. The parties undertake not to
commence any suit, action or proceeding arising out of or relating to this Agreement in a forum other than a forum described in this Section 16.02(a); provided, however, that nothing herein shall preclude the Company from bringing
any suit, action or proceeding in any other court for the purposes of enforcing any judgment obtained by the Company and, in such event, the Executive hereby irrevocably submits to the jurisdiction of such other court. 
  

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 (b) The agreement of the parties to the forum described in Section 16.02(a) is
independent of the law that may be applied in any suit, action, or proceeding and the parties agree to such forum even if such forum may under applicable law choose to apply non-forum law. The parties hereby waive, to the fullest extent permitted by
applicable law, any objection which they now or hereafter have to personal jurisdiction or to the laying of venue of any such suit, action or proceeding brought in an applicable court described in Section 16.02(a), and each party agrees that it
shall not attempt to deny or defeat such personal jurisdiction by motion or other request for leave from any such court. The parties agree that, to the fullest extent permitted by applicable law, a final and non-appealable judgment in any suit,
action or proceeding brought in any applicable court described in Section 16.02(a) shall be conclusive and binding upon the parties and may be enforced in any other jurisdiction. 
 (c) Each party hereto irrevocably consents to the service of any and all process in any suit, action or proceeding arising out of or
relating to this Agreement by the mailing of copies of such process to such party at such party’s address specified in Article XII. 
 ARTICLE XVII 
 General Provisions 
 SECTION 17.01. The Company and the Executive intend that the benefits and payments described in this Agreement shall comply with, or be exempt from, the
requirements of Section 409A of the Code (“Section 409A”). The Company shall in no event be obligated to indemnify the Executive for any taxes or interest that may be assessed by the IRS pursuant to Section 409A of the Code.

 SECTION 17.02. This Executive Termination Agreement shall not be construed as creating an express or implied contract of employment and,
except as otherwise agreed in writing between the Executive and the Company, the Executive shall not have any right to be retained in the employ of the Company. 
 SECTION 17.03. No right or interest to or in any payments shall be assignable by the Executive; provided, however, that this provision shall not preclude the Executive from designating one or more
beneficiaries to receive any amount that may be payable after the Executive’s death and shall not preclude the legal representative of the Executive’s estate from assigning any right hereunder to the person or persons entitled thereto
under the Executive’s will or, in the case of intestacy, to the person or persons entitled thereto under the laws of intestacy applicable to the Executive’s estate. 
 SECTION 17.04. No right, benefit or interest hereunder shall be subject to anticipation, alienation, sale, assignment, encumbrance, charge, pledge,
hypothecation, or set-off in respect of any claim, debt or obligation, or to execution, attachment, levy or similar process, or assignment by operation of law. Any attempt, voluntary or involuntary, to effect any action specified in the immediately
preceding sentence shall, to the full extent permitted by law, be null, void and of no effect. 
  

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 SECTION 17.05. The invalidity or unenforceability of any provisions of this Agreement shall not affect
the validity or enforceability of any other provisions of this Agreement, which shall remain in full force and effect to the fullest extent permitted by law. The Executive agrees that in the event that any court of competent jurisdiction shall
finally hold that any provision of this Agreement (whether in whole or in part) is void or constitutes an unreasonable restriction against the Executive, such provision shall not be rendered void but shall be deemed to be modified to the minimum
extent necessary to make such provision enforceable for the longest duration and the greatest scope as such court may determine constitutes a reasonable restriction under the circumstances. 
 SECTION 17.06. This Agreement supersedes and replaces the Executive Termination Agreement dated January 9, 2006 and any and all prior severance
agreements (but expressly excluding the Severance Agreement) between the Company and the Executive entered into before the date of this Agreement (the “Prior Agreements”). By signing this Agreement, the Executive acknowledges that the
Prior Agreements are terminated and cancelled, and releases and discharges the Company from any and all obligations and liabilities heretofore or now existing under or by virtue of such Prior Agreements, it being the intention of the parties hereto
that this Agreement effective immediately shall supersede and be in lieu of the Prior Agreements. By signing this Agreement, the Executive further acknowledges that this Executive Termination Agreement shall supersede and replace any rights the
Executive may have had to an enhancement of any supplemental retirement benefits under the Supplemental Retirement Savings Plan for Key Employees of Millipore Corporation on a termination of the Executive’s employment. It is specifically
acknowledged by the Company that this Agreement does not supersede the Severance Agreement. 
 SECTION 17.07. The Company may withhold from
any amounts payable under this Agreement such Federal, state, local, foreign or other taxes as are required to be withheld pursuant to any applicable law or regulation. 
 SECTION 17.08. The headings of this Agreement are inserted for convenience only and neither constitute a part of this Agreement nor affect in any way the meaning or interpretation of this Agreement. When a reference
in this Agreement is made to a Section, such reference shall be to a Section of this Agreement unless otherwise indicated. The section headings used in this Agreement are included solely for convenience and shall not affect, or be used in connection
with, the interpretation of this Agreement. If there is any inconsistency between this Executive Termination Agreement and any other agreement (including but not limited to any option, stock, long-term incentive or other equity award agreement),
plan, program, policy or practice (collectively, “Other Provision”) of the Company the terms of this Executive Termination Agreement shall control over such Other Provision. 
 SECTION 17.09. This Executive Termination Agreement may be executed in one or more counterparts (including via facsimile), each of which shall be deemed
to be an original, but all of which together shall constitute one and the same instrument and shall become effective when one or more counterparts have been signed by each of the parties and delivered to the other parties. 
  

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 SECTION 17.10. The language used in this Executive Termination Agreement will be deemed to be the
language chosen by the parties hereto to express their mutual intent, and no rule of strict construction will be applied against any party hereto. Neither the Executive nor the Company shall be entitled to any presumption in connection with any
determination made hereunder in connection with any arbitration, judicial or administrative proceeding relating to or arising under this Agreement. 
 SECTION 17.11. The Executive represents and warrants to the Company that the Executive has the legal right to enter into this Executive Termination Agreement and to perform all of the obligations on the Executive’s part to be performed
hereunder in accordance with its terms and that the Executive is not a party to any agreement or understanding, written or oral, which could prevent the Executive from entering into this Executive Termination Agreement or performing all of the
Executive’s obligations hereunder. 
 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the day and year first above written.

  

			
	MILLIPORE CORPORATION
		
	By	 	 /s/ Martin D. Madaus

	Name:	 	Martin D. Madaus
	Title:	 	President and Chief Executive Officer
	
	 /s/ Jean-Paul Mangeolle

	Jean-Paul Mangeolle
		
	Date:	 	9/10/07

  

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 EXHIBIT A 
 DEFINITIONS 
 “Cause” means any of the following: 
 (a) repeated and documented failure or refusal, without proper legal cause, to perform the duties and responsibilities of the
Executive’s position; 
 (b) the Executive’s conviction, indictment or entering into a guilty plea or a plea of no
contest (or their procedural equivalent) for any felony or other crime with respect to which imprisonment is reasonably likely; 
 (c) the Executive’s misappropriation or embezzlement of funds or property belonging to the Company; 
 (d) the
appropriation (or attempted appropriation) of a material business opportunity of the Company, including attempting to secure or securing any personal profit in connection with any transaction entered into on behalf of the Company; 
 (e) the Executive’s engaging in activities that constitute a material breach or violation of any of the terms of this Agreement or
Employee Code of Conduct (including its Rules of Conduct) dated as of October 26, 2006, and as may be awarded from time to time; 
 (f) chronic absenteeism not caused by Disability; 
 (g) engaging in sexual harassment in
violation of applicable federal, state or local laws or the Company’s employment policies; or 
 (h) controlled substance
abuse, alcoholism or drug addiction that interferes with or affects the Executive’s responsibilities to the Company or that reflects negatively upon the Company’s integrity or reputation. 
 The Executive shall have a reasonable period of time (but in no event less than 15 days) to cure any material breach described in paragraph
(e) above; provided, however, that the Board shall not be required to provide the Executive an opportunity to cure a material breach under paragraph (e) above if it reasonably determines that such breach is not capable of being cured.
Cause does not include any act or omission of which any member of the Board who is not a party to such act or omission has had actual knowledge for at least six (6) months. Any notice to terminate the Executive employment for Cause must state
that the Board finds in good faith that (1) the Executive is guilty of conduct constituting Cause, specifying the details of such conduct, and (2) solely with respect to a material breach under paragraph (e), that either (x) the
Executive failed to timely cure such breach to the Board’s reasonable satisfaction, or (y) such breach was not capable of being cured. 
  

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 “Change of Control” shall mean the first to occur of the following events, provided that such
event is not a Management Buyout: 
 (a) any “person” (as such term is defined in Section 3(a)(9) of the
Securities Exchange Act of 1934, as amended (the “Exchange Act”), and as used in Sections 13(d)(3) and 14(d)(2) of the Exchange Act) is or becomes a “beneficial owner” (as defined in Rule 13d-3 under the Exchange Act), directly
or indirectly, of securities of the Company representing 30% or more of the combined voting power of the Company’s then outstanding securities eligible to vote for the election of the Board (the “Company Voting Securities”);
provided, however, that the event described in this paragraph (a) shall not be deemed to be a Change of Control if such event results from any of the following: (i) the acquisition of Company Voting Securities by the Company
or any of its subsidiaries, (ii) the acquisition of Company Voting Securities by any employee benefit plan (or related trust) sponsored or maintained by the Company or any of its subsidiaries, (iii) the acquisition of Company Voting
Securities by any underwriter temporarily holding securities pursuant to an offering of such securities, or (iv) the acquisition of Company Voting Securities pursuant to a Non-Qualifying Transaction (as defined in paragraph (c) below);

 (b) individuals who, as of the date hereof, constitute the Board (the “Incumbent Directors”) cease for any reason
to constitute at least a majority of the Board; provided, however, that any individual becoming a director subsequent to the date hereof, whose election or nomination for election was endorsed (either by a specific vote or by approval
of the proxy statement of the Company in which such individual is named as a nominee for director, without written objection to such nomination) by a vote of at least a majority of the directors who were, as of the date of such approval, Incumbent
Directors, shall be an Incumbent Director; provided, however, that no individual initially appointed, elected or nominated as a director of the Company as a result of an actual or threatened election contest with respect to the
election or removal of directors or as a result of any other actual or threatened solicitation of proxies or consents by or on behalf of any person other than the Board shall be an Incumbent Director; or 
 (c) the consummation of a merger, consolidation, statutory share exchange or similar form of corporate transaction involving (i) the
Company or (ii) any of its wholly owned subsidiaries pursuant to which, in the case of this clause (ii), Company Voting Securities are issued or issuable (any event described in the immediately preceding clause (i) or (ii), a
“Reorganization”) or (iii) the sale or other disposition of all or substantially all of the assets of the Company to an entity that is not an affiliate of the Company (it being understood that this clause (iii) will only be
triggered upon a sale of assets having a total gross fair market value equal to or more than 40% of the total gross fair market value of all the Company’s assets immediately before such acquisition) (a “Sale”), unless immediately
following such Reorganization or Sale: (A) more than 50% of the total voting power (in respect of the election of directors, or similar officials in the case of an entity other than a corporation) of (x) the entity resulting from such
Reorganization, or the entity which has acquired all or substantially all of the assets of the Company (in either case, the “Surviving Entity”), or (y) if applicable, the ultimate parent entity that directly or indirectly has
beneficial ownership of more than 50% of the total 

  

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voting power (in respect of the election of directors, or similar officials in the case of an entity other than a corporation) of the Surviving Entity (the
“Parent Entity”), is represented by Company Voting Securities that were outstanding immediately prior to such Reorganization or Sale (or, if applicable, is represented by shares into which such Company Voting Securities were converted
pursuant to such Reorganization or Sale), (B) no person (other than any employee benefit plan (or related trust) sponsored or maintained by the Surviving Entity or the Parent Entity) is or becomes the beneficial owner, directly or indirectly,
of 30% or more of the total voting power (in respect of the election of directors, or similar officials in the case of an entity other than a corporation) of the outstanding voting securities of the Parent Entity (or, if there is no Parent Entity,
the Surviving Entity) and (C) at least a majority of the members of the board of directors (or similar officials in the case of an entity other than a corporation) of the Parent Entity (or, if there is no Parent Entity, the Surviving Entity)
following the consummation of the Reorganization or Sale were, at the time of the approval by the Board of the execution of the initial agreement providing for such Reorganization or Sale, Incumbent Directors (any Reorganization or Sale which
satisfies all of the criteria specified in (A), (B) and (C) above shall be deemed to be a “Non-Qualifying Transaction”); or 
 (d) the stockholders of the Company approve a plan of complete liquidation or dissolution of the Company. 
 Notwithstanding
the foregoing, if any person becomes the beneficial owner of 30% or more of the combined voting power of Company Voting Securities solely as a result of the acquisition of Company Voting Securities by the Company which reduces the number of Company
Voting Securities outstanding, such increased amount shall be deemed not to result in a Change of Control; provided, however, that if such person subsequently becomes the beneficial owner of additional Company Voting Securities that
increases the percentage of outstanding Company Voting Securities beneficially owned by such person, a Change of Control shall then be deemed to occur. 
 “Code” shall mean the Internal Revenue Code of 1986, as amended. 
 “Company” means
Millipore Corporation and, for purposes of the definition of “Cause” shall include its subsidiaries and affiliates. 
 “Consultant” shall have the meaning set forth in Exhibit C of this Agreement. 
 “Date of Termination”, with
respect to any purported termination of the Executive’s employment after a Change of Control, means (a) if the Executive’s employment is terminated for Disability, 30 days after Notice of Termination is given (provided that the
Executive has not returned to the performance of the Executive’s duties on a full-time basis during such 30-day period), (b) if the Executive’s employment is terminated by the Company for any reason other than Disability or by the
Executive for any reason, the date specified in the Notice of Termination (which, in the case of a termination by the Company shall not be less than 30 days, and in the case of a termination by the Executive shall not be more than 60 days,
respectively, from the date such Notice of Termination is given) or (c) if the Executive dies, the Executive’s date of death (without any requirement that a Notice of Termination be provided), subject in each case to Section 11.02.

  

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 “Disability” means if, for physical or mental reasons, the Executive is unable to perform the
Executive’s duties under this Agreement for 120 consecutive days, or 180 days during any twelve-month period, as reasonably determined by the Board. 
 “Excise Tax” shall mean any excise tax imposed under Section 4999 of the Code. 
 “Good
Reason” shall mean the occurrence (without the Executive’s express written consent) after a Change of Control of any one of the following acts by the Company, or failures by the Company to act, unless such act or failure to act is
corrected in accordance with the procedures described below: 
 (a) the assignment to the Executive of any duties inconsistent
with the Executive’s status as Corporate Vice President and President of Bioprocess Division of the Company or a substantial diminution in the nature or status of the Executive’s responsibilities from those in effect immediately prior to
the Change of Control (for the avoidance of doubt, a change in reporting relationships shall not be considered a substantial diminution in the nature or status of the Executive’s responsibilities); 
 (b) a reduction by the Company in the Executive’s annual base salary and/or the level of the Executive’s target bonus under the
Company’s annual bonus plan, in each case as in effect as of immediately prior to a Change of Control or as the same may be increased from time to time; 
 (c) the Company’s requiring the Executive to be based anywhere outside a fifty mile radius of the Company’s offices at which the
Executive is based as of immediately prior to a Change of Control (or any subsequent location at which the Executive has previously consented to be based) except for required travel on the Company’s business to an extent that is not
substantially greater than the Executive’s business travel obligations as of immediately prior to a Change of Control or, if more favorable, as of any time thereafter, or, in the event the Executive consents to any such relocation of the
Executive’s offices, the failure by the Company to provide the Executive with all of the benefits of the Company’s relocation policy, if any, as in effect as of immediately prior to a Change of Control or, if more favorable as of any time
thereafter; 
 (d) the failure by the Company to pay to the Executive any portion of the Executive’s current compensation
(for purposes of this paragraph (d), “current compensation” shall mean the Executive’s annual base salary and the awards earned pursuant to the Company’s annual bonus plan, in each case as in effect as of immediately prior
to a Change of Control or as the same may be increased from time to time) or to pay to the Executive any portion of an installment of deferred compensation under any deferred compensation program of the Company as in effect as of immediately prior
to a Change of Control or, if more favorable, as of any time thereafter, within seven days of the date such compensation is due; 
 (e) the failure by the Company to continue in effect any short-term and long-term cash compensation and stock-based compensation plan in which the Executive participates as of immediately prior to a Change of Control or, if more favorable,
as of any time thereafter, unless an equitable arrangement (embodied in an ongoing substitute 

  

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or alternative plan) has been made with respect to such plan, or the failure by the Company to continue the Executive’s participation therein (or in
such substitute or alternative plan) on a basis not less favorable, both in terms of the amount of benefits provided and the level of the Executive’s participation relative to other participants as existed as of immediately prior to a Change of
Control or, if more favorable, as of any time thereafter; 
 (f) the failure by the Company to continue to provide the
Executive with benefits no less favorable in the aggregate than those enjoyed by the Executive under any of the Company’s life insurance, medical, health and accident, or disability plans in which the Executive was participating as of
immediately prior to a Change of Control or, if more favorable, as of any time thereafter, (ii) the taking of any action by the Company which would directly or indirectly reduce any of such benefits or deprive the Executive of any fringe
benefit enjoyed by the Executive as of immediately prior to a Change of Control or, if more favorable, as of any time thereafter, or (iii) the failure by the Company to provide the Executive with the number of paid vacation days to which the
Executive is entitled on the basis of years of service with the Company in accordance with the Company’s normal vacation policy in effect as of immediately prior to a Change of Control or, if more favorable, as of any time thereafter;
provided, however that this paragraph shall not be construed to require the Company to provide the Executive with a defined benefit pension plan if no such plan is provided to similarly situated executive officers of the Company; or

 (g) any purported termination of the Executive’s employment which is not effected pursuant to a Notice of Termination
satisfying the requirements of Section 11.01, and, for purposes of this Agreement, no such purported termination shall preclude the Executive from claiming Good Reason hereunder. 
 The Executive’s right to terminate the Executive’s employment for Good Reason shall not be affected by the Executive’s incapacity due to physical or mental illness. The Executive will be deemed to have
waived the Executive’s rights relating to circumstances constituting Good Reason if the Executive has not provided to the Company a written Notice of Termination within ninety (90) days following the Executive’s knowledge of
circumstances constituting Good Reason. If the condition giving rise to Good Reason is capable of being corrected, the Company shall have 30 days during which it may remedy the condition to the reasonable satisfaction of the Executive. 

“Gross-Up Payment” shall have the meaning set forth in Section 8.01 of this Agreement. 
 “Impending Change of Control” means the occurrence of any event or circumstance which gives rise to a threat or a likelihood of Change of
Control, whether or not supported or approved by the Company’s management or the Board, provided that an Impending Change of Control shall be deemed to have occurred if: 
 (a) the Company enters into an agreement, the consummation of which would result in the occurrence of a Change of Control; 
  

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 (b) the Company or any person (as defined for purposes of a Change of Control), publicly
announces an intention to take or to consider taking actions which, if consummated, would constitute a Change of Control; 
 (c) any person (other than any person described in paragraph (a)(i), (ii) or (iii) of the definition of a Change of Control) (i) who is the beneficial owner, as of the date hereof, directly or indirectly, 15% or more of the
combined voting power of the Company Voting Securities, increases such person’s beneficial ownership of Company Voting Securities or (ii) who beneficially owns, as of the date hereof, directly or indirectly, less than 15% of the combined
voting power of the Company Voting Securities, becomes the beneficial owner of 15% or more of the combined voting power of the Company Voting Securities; or 
 (d) the Board adopts a resolution to the effect that, for purposes of this Agreement, an Impending Change of Control has occurred.

 Notwithstanding the foregoing, if any person becomes the beneficial owner of an additional amount of the combined voting power of Company Voting
Securities solely as a result of the acquisition of Company Voting Securities by the Company which reduces the number of Company Voting Securities outstanding, such increased amount shall be deemed not to result in an Impending Change of Control;
provided, however, that if such person subsequently becomes the beneficial owner of additional Company Voting Securities that increases the percentage of outstanding Company Voting Securities beneficially owned by such person, an
Impending Change of Control shall then be deemed to occur.  
 Any determination made by the Board that an event constituting an Impending Change of
Control has occurred shall be final and binding if such determination is made by the Board in good faith. 
 “Management Buyout”
shall mean an event or transaction which would otherwise constitute a Change of Control (a “Transaction”) if, in connection with the Transaction, the Executive, members of the Executive’s immediate family, and/or the
“Executive’s Affiliates” (as defined below) participate, directly or beneficially, as an equity investor in, or have the option or right to acquire, whether or not vested, equity interests of, the acquiring entity or any of its
Affiliates (the “Acquiror”) having a percentage interest therein greater than three percent. For purposes of the preceding sentence, a party shall not be deemed to have participated as an equity investor in the Acquiror by virtue of
(i) obtaining beneficial ownership of any equity interest in the Acquiror as a result of the grant to the party of an incentive compensation award under one or more incentive plans of the Acquiror (including, but not limited to, the conversion
in connection with the Transaction of incentive compensation awards of the Company into incentive compensation awards of the Acquiror), on terms and conditions substantially equivalent to those applicable to other employees of the Company at a
comparable level as such party immediately prior to the Transaction, or at other peer group life science companies customarily referenced as such in the Company’s proxy statement disclosures, after taking into account normal differences
attributable to job responsibilities, title and the like, or (ii) obtaining beneficial ownership of any equity interest in the Acquiror on terms and conditions substantially equivalent to those obtained in the Transaction by all other
shareholders of the Company or (iii) the party’s interests in any tax-qualified defined benefit or defined contribution pension or retirement plan in which such 

  

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party or any family member is a participant or beneficiary. The “Executive’s Affiliates “ at any time consist of any entity in which the
Executive and/or members of the Executive’s immediate family then own, directly or beneficially, or have the option or right to acquire, whether or not vested, greater than 10% of such entity’s equity interests, and all then current
directors and executive officers of the Company who are members of any group, that also includes the Executive, a member of the Executive’s immediate family and/or any such entity, in which the members have agreed to act together for the
purpose of participating in the Transaction. The Executive’s immediate family consists of the Executive’s spouse, parents, children and grandchildren. 
 “Notice of Termination” shall mean a notice which indicates the specific termination provision in this Agreement relied upon and sets forth in reasonable detail the facts and circumstances claimed to provide
a basis for termination of the Executive’s employment under the provision so indicated. A Notice of Termination for Cause is required to include a copy of a resolution duly adopted by the affirmative vote of not less than three-quarters
(3/4) of the entire membership of the Board (excluding the Executive for such purpose) at a meeting of the Board which was called and held for the purpose of considering such termination (after reasonable notice to the Executive and an
opportunity for the Executive, together with the Executive’s counsel, to be heard before the Board) finding that, in the good faith opinion of the Board, the Executive’s conduct constituted Cause, and specifying the particulars thereof in
detail. 
 “Payments” shall have the meaning set forth in Section 8.01 of this Agreement. 
 “Period of Employment” shall mean the period beginning upon the occurrence of an Impending Change of Control (or, if a Change of Control occurs
prior to any Impending Change of Control, upon a Change of Control) and ending at the close of business on the 180th day subsequent to any Change of Control (or, if earlier, the date on which the Board determines that there is no longer any threat
or likelihood of a Change of Control). 
 “Qualifying Termination” shall have the meaning given such term in Section 5.01, For
avoidance of doubt, a suspension of the Executive’s title and authority while on administrative leave due to a reasonable belief that the Executive has engaged in misconduct, whether or not the suspected misconduct constitutes Cause for
employment termination, shall not be considered a constructive termination of employment. 
 “Severance Agreement” shall mean that
certain Officer Severance Agreement, dated as of the date hereof, between the Executive and the Company. 
 “Severance Payments”
shall have the meaning given such term in Section 5.01. 
 “Stock Award” means stock options, restricted stock, stock
appreciation rights, phantom stock and any other similar award initially issued to the Executive before, on or after the date of this Agreement but before a Change of Control that has its value based on the Company’s common stock. 

 

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 EXHIBIT B 
 FORM OF RELEASE AGREEMENT 
 AGREEMENT AND GENERAL RELEASE 
 Millipore Corporation, its affiliates, parents, subsidiaries, divisions, successors and assigns in such capacity, and the current, future and former
employees, officers, directors, trustees and agents thereof (collectively referred to throughout this Agreement as “Employer”), and
                                 (“Executive”), the Executive’s
heirs, executors, administrators, successors and assigns (collectively referred to throughout this Agreement as “Employee”) agree: 
 1. Last Day of Employment. Executive’s last day of employment with Employer is
                            . In addition, effective as of DATE, Executive resigns from the
Executive’s position as                                  and will not be
eligible for any benefits or compensation after                     , other than as specifically provided in Article IV, Article V and
Section 6.01 of the Executive Termination Agreement between Employer and Executive dated
                             (the “Executive Termination Agreement”). The Executive
further acknowledges and agrees that, after DATE, the Executive will not represent the Executive as being a director, employee, officer, trustee, agent or representative of Employer for any purpose. In addition, effective as of DATE, Executive
resigns from all offices, directorships, trusteeships, committee memberships and fiduciary capacities held with, or on behalf of, Employer or any benefit plans of Employer. These resignations will become irrevocable as set forth in Section 3
below. 
 2. Consideration. The parties acknowledge that this Agreement and General Release is being executed in accordance with
Section 7.02(b) of the Executive Termination Agreement. 
 3. Revocation. Executive may revoke this Agreement and General Release for a
period of seven (7) calendar days following the day Executive executes this Agreement and General Release. Any revocation within this period must be submitted, in writing, to Employer and state, “I hereby revoke my acceptance of our
Agreement and General Release.” The revocation must be personally delivered to Employer’s
                                        ,
and postmarked within seven (7) calendar days of execution of this Agreement and General Release. This Agreement and General Release shall not become effective or enforceable until the revocation period has expired. If the last day of the
revocation period is a Saturday, Sunday, or legal holiday in Boston, Massachusetts, then the revocation period shall not expire until the next following day which is not a Saturday, Sunday, or legal holiday. 
 4. General Release of Claim. Subject to the full satisfaction by the Employer of its obligations under the Severance Agreement, Employee knowingly and
voluntarily releases and forever discharges Employer from any and all claims, causes of action, demands, fees and liabilities of any kind whatsoever, whether known and unknown, against Employer, Employee has, has ever had or may have as of the date
of execution of this Agreement and General Release, including, but not limited to, any alleged violation of: 
  

	 	•	 	 Title VII of the Civil Rights Act of 1964, as amended; 

  

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	 	•	 	 The Civil Rights Act of 1991; 

  

	 	•	 	 Sections 1981 through 1988 of Title 42 of the United States Code, as amended; 

  

	 	•	 	 The Employee Retirement Income Security Act of 1974, as amended; 

  

	 	•	 	 The Immigration Reform and Control Act, as amended; 

  

	 	•	 	 The Americans with Disabilities Act of 1990, as amended; 

  

	 	•	 	 The Age Discrimination in Employment Act of 1967, as amended; 

  

	 	•	 	 The Older Workers Benefit Protection Act of 1990; 

  

	 	•	 	 The Worker Adjustment and Retraining Notification Act, as amended; 

  

	 	•	 	 The Occupational Safety and Health Act, as amended; 

  

	 	•	 	 The Family and Medical Leave Act of 1993; 

  

	 	•	 	 Any wage payment and collection, equal pay and other similar laws, acts and statutes of the Commonwealth of Massachusetts; 

  

	 	•	 	 Any other federal, state or local civil or human rights law or any other local state or federal law, regulation or ordinance; 

  

	 	•	 	 Any public policy, contract, tort, or common law; or 

  

	 	•	 	 Any allegation for costs, fees, or other expenses including attorneys fees incurred in these matters. 

 Notwithstanding anything herein to the contrary, the sole matters to which the Agreement and General Release do not apply are: (i) Employee’s express rights to
accrued vested benefits under any other employee benefit plan, policy or arrangement maintained by Employer or under COBRA (the “Accrued Amounts”); (ii) Employee’s rights under the provisions of the Executive Termination
Agreement which are intended to survive termination of employment; or (iii) the Employee’s rights as a stockholder. 
 5. No Claims
Permitted. Employee waives Executive’s right to file any charge or complaint against Employer arising out of Executive’s employment with or separation from Employer before any federal, state or local court or any state or local
administrative agency, except where such waivers are prohibited by law. 
 6. Affirmations. Employee affirms Executive has not filed, has not
caused to be filed, and is not presently a party to, any claim, complaint, or action against Employer in any forum. Employee further affirms that the Executive has been paid and/or has received all compensation, wages, bonuses, commissions, and/or
benefits to which Executive may be entitled and no other compensation, wages, bonuses, commissions and/or benefits are due to Executive, except for the Accrued Amounts. The Employee also affirms Executive has no known workplace injuries. 

 

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 7. Cooperation; Return of Property. In accordance with Section 5.10 of the Severance Agreement,
Employee agrees to reasonably cooperate with Employer and its counsel in connection with any investigation, administrative proceeding or litigation relating to any matter that occurred during Executive’s employment in which Executive was
involved or of which Executive has knowledge. Employee represents that Executive has complied with Section 5.08 of the Severance Agreement regarding the return of property. 
 8. Governing Law and Interpretation. This Agreement and General Release shall be governed and conformed in accordance with the laws of the Commonwealth
of Massachusetts without regard to its conflict of laws provisions. In the event Employee or Employer breaches any provision of this Agreement and General Release, Employee and Employer affirm either may institute an action to specifically enforce
any term or terms of this Agreement and General Release. Should any provision of this Agreement and General Release be declared illegal or unenforceable by any court of competent jurisdiction and should the provision be incapable of being modified
to be enforceable, such provision shall immediately become null and void, leaving the remainder of this Agreement and General Release in full force and effect. Nothing herein, however, shall operate to void or nullify any general release language
contained in the Agreement and General Release. 
 9. No Admission of Wrongdoing. Employee agrees neither this Agreement and General Release
nor the furnishing of the consideration for this Release shall be deemed or construed at any time for any purpose as an admission by Employer of any liability or unlawful conduct of any kind. 
 10. Amendment. This Agreement and General Release may not be modified, altered or changed except upon express written consent of both parties wherein
specific reference is made to this Agreement and General Release. 
 11. Entire Agreement. This Agreement and General Release sets forth the
entire agreement between the parties hereto and fully supersedes any prior agreements or understandings between the parties; provided, however, that notwithstanding anything in this Agreement and General Release, the provisions in the
Executive Termination Agreement which are intended to survive termination of the Executive’s employment, such as under Article IX, shall survive and continue in full force and effect. Employee acknowledges Executive has not relied on any
representations, promises, or agreements of any kind made to Executive in connection with Executive’s decision to accept this Agreement and General Release. 
 EMPLOYEE HAS BEEN ADVISED THAT EXECUTIVE HAS UP TO TWENTY-ONE (21) CALENDAR DAYS TO REVIEW THIS AGREEMENT AND GENERAL RELEASE AND HAS BEEN ADVISED IN WRITING TO CONSULT WITH AN ATTORNEY PRIOR TO EXECUTION OF THIS AGREEMENT AND GENERAL
RELEASE. 
 EMPLOYEE AGREES ANY MODIFICATIONS, MATERIAL OR OTHERWISE, MADE TO THIS AGREEMENT AND GENERAL RELEASE DO NOT RESTART OR AFFECT IN ANY MANNER THE
ORIGINAL TWENTY-ONE (21) CALENDAR DAY CONSIDERATION PERIOD. 
  

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 HAVING ELECTED TO EXECUTE THIS AGREEMENT AND GENERAL RELEASE, TO FULFILL THE PROMISES SET FORTH HEREIN, AND TO RECEIVE
THE SUMS AND BENEFITS SET FORTH IN THE SEVERANCE AGREEMENT, EMPLOYEE FREELY AND KNOWINGLY, AND AFTER DUE CONSIDERATION, ENTERS INTO THIS AGREEMENT AND GENERAL RELEASE INTENDING TO WAIVE, SETTLE AND RELEASE ALL CLAIMS EXECUTIVE HAS OR MIGHT HAVE
AGAINST EMPLOYER. 
 IN WITNESS WHEREOF, the parties hereto knowingly and voluntarily executed this Agreement and General Release as of the date set forth
below: 
  

			
	MILLIPORE CORPORATION
		
	By:	 	  

		
	Name:	 	[NAME]
	Title:	 	  

	Date:	 	  

	
	EXECUTIVE
	
	  

		
	Date:	 	  

  

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 EXHIBIT C 
 TAX GROSS-UP PAYMENT RULES AND PROCEDURES 
 1. Subject to Paragraph 3 below, all determinations
required to be made under Section 8.02 of this Agreement, including whether a Gross-Up Payment is required and the amount of such Gross-Up Payment, shall be made by an accounting firm (the “Consultant”) selected in accordance with
Paragraph 2 below. The Consultant shall provide detailed supporting calculations both to the Company and Executive within 15 business days of the event that results in the potential for an excise tax liability for the Executive, which could include
but is not limited to a Change of Control and the subsequent vesting of any cash payments or awards, or the Executive’s termination of employment, or such earlier time as is required by the Company. The initial Gross-Up Payment, if any, as
determined pursuant to this Paragraph 1, shall be paid on the Executive’s behalf to the applicable taxing authorities within five (5) days of the receipt of the Consultant’s determination. If the Consultant determines that the
Executive is not subject to Excise Tax, it shall furnish the Executive with a written report indicating that the Executive has substantial authority not to report any Excise Tax on the Executive’s federal income tax return. Any determination by
the Consultant shall be binding upon the Company and Executive. As a result of the uncertainty in the application of Section 4999 of the Code at the time of the initial determination by the Consultant hereunder, it is possible that Gross-Up
Payments which will not have been made by the Company should have been made (“Underpayment”), consistent with the calculations required to be made hereunder. In the event that the Company exhausts its remedies pursuant to Paragraph 3 below
and Executive thereafter is required to make a payment or additional payment of any Excise Tax, the Consultant shall determine the amount of the Underpayment that has occurred and any such Underpayment, increased by all applicable interest and
penalties associated with the Underpayment, shall be promptly paid by the Company to or for the benefit of Executive. For purposes of determining the amount of the Gross-Up Payment, Executive shall be deemed to pay federal income tax at the highest
marginal rate of federal income taxation in the calendar year in which the Gross-Up Payment is to be made and state and local income taxes on earned income at the highest marginal rate of taxation in the state and locality of Executive’s
residence on the Date of Termination, (or the date of the Change of Control if the Executive is subject to Excise Tax prior to the issuance of a Notice of Termination) net of the maximum reduction in federal income taxes which could be obtained from
deduction of such state and local taxes. 
 2. The Consultant shall be a nationally recognized public accounting firm, benefits consultant or
law firm proposed by the Company and agreed upon by the Executive. If Executive and the Company cannot agree on the firm to serve as the Consultant within ten (10) days after the date on which the Company proposed to Executive an entity to
serve as the Consultant, then Executive and the Company shall each select one and those two firms shall jointly select the entity to serve as the Consultant within ten (10) days after being requested by the Company and Executive to make such
selection. The Company shall pay the Consultant’s fee. 
 3. Executive shall notify the Company in writing of any claim by the Internal
Revenue Service that, if successful, would require the payment by the Company of the Gross-Up Payment. Such notification shall be given as soon as practicable, but no later than fifteen (15)

  

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business days after Executive knows of such claim and the Executive shall apprise the Company of the nature of such claim and the date on which such claim is
requested to be paid. Executive shall not pay such claim prior to the expiration of the period ending on the date that any payment of taxes with respect to such claim is due or the thirty day period following the date on which Executive gives such
notice to the Company, whichever period is shorter. If the Company notifies Executive in writing prior to the expiration of such period that it desires to contest such claim, Executive shall (i) give the Company any information reasonably
requested by the Company relating to such claim, (ii) take such action in connection with contesting such claim as the Company shall reasonably request in writing from time to time, including, without limitation, accepting legal representation
with respect to such claim by an attorney reasonably selected by the Company, (iii) cooperate with the Company in good faith in order effectively to contest such claim, and (iv) permit the Company to participate in any proceedings relating
to such claim; provided, however, that the Company shall bear and pay directly all costs and expenses (including attorneys fees and any additional interest and penalties) incurred in connection with such contest and shall indemnify and
hold Executive harmless, on an after-tax basis, for any Excise Tax or income tax, including interest and penalties with respect thereto, imposed as a result of such representation and payment of costs and expenses. Without limitation of the
foregoing provisions of this Paragraph 3, the Company shall control all proceedings taken in connection with such contest and, at its sole option, may pursue or forego any and all administrative appeals, proceedings, hearings and conferences with
the taxing authority in respect to such claim and may, at its sole option, either direct Executive to pay the tax claimed and sue for a refund or contest the claim in any permissible manner, and Executive agrees to prosecute such contest to a
determination before any administrative tribunal, in a court of initial jurisdiction and in one or more appellate courts, as the Company shall determine; provided, however, that if the Company directs Executive to pay such claim and
sue for a refund, the Company shall advance the amount of such payment to Executive, on an interest-free basis and shall indemnify and hold Executive harmless, on an after-tax basis, from any Excise Tax and income tax, including interest or
penalties with respect thereto, imposed with respect to such advance or with respect to any imputed income with respect to such advance; and further provided that any extension of the statute of limitations relating to payment of taxes for the
taxable year of Executive with respect to which such contested amount is claimed to be due is limited solely to such contested amount. Furthermore, the Company’s control of the contest shall be limited to issues with respect to which a Gross-Up
Payment would be payable hereunder and Executive shall be entitled to settle or contest, as the case may be, any other issue raised by the Internal Revenue Service or any other authority. 
 4. If, after the receipt by Executive of an amount advanced by the Company pursuant to Paragraph 3 above, Executive becomes entitled to receive any
refund with respect to such claim, Executive shall (subject to the Company’s complying with the requirements of Paragraph 3), promptly pay to the Company the amount of such refund (together with any interest paid or credited thereon after taxes
applicable thereto). 
 5. Any Gross-Up Payment required to be paid hereunder shall be paid no later than the end of the Executive’s
taxable year next following the Executive’s taxable year in which the Executive pays the Excise Tax to which the Gross-Up Payment relates to the United States Internal Revenue Service or other applicable taxing authority. 
  

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