Document:

Avantogen Oncology, Inc. 2006 Stock Incentive Plan

 Exhibit 10.1 
 AVANTOGEN ONCOLOGY, INC. 
 2006 STOCK INCENTIVE PLAN 

 AVANTOGEN ONCOLOGY, INC. 
 2006 STOCK INCENTIVE PLAN 
  

	1.	ESTABLISHMENT AND PURPOSE. 

 The Avantogen Oncology, Inc.
2006 Stock Incentive Plan (the “Plan”) is established by Avantogen Oncology, Inc., a Nevada corporation (the “Company”), to attract and retain persons eligible to participate in the Plan; motivate Participants to
achieve long-term Company goals; and further align Participants’ interests with those of the Company’s other stockholders. The Plan is adopted as of August 7, 2006, subject to approval by the Company’s stockholders within 12
months after such adoption date. No Awards shall be granted hereunder prior to the approval of the Plan by the Company’s stockholders. No Award shall be granted hereunder on or after the date 10 years after the Effective Date or such earlier
date as of which the Plan is discontinued by the Board as provided herein. The Plan shall terminate on August 6, 2016 or such earlier time as the Board may determine. 
 Certain terms used herein are defined as set forth in Section 9. 
  

	2.	ADMINISTRATION; ELIGIBILITY. 

 The Plan shall be administered
by the Compensation Committee of the Board, or such other Committee, appointed by the Board consisting of two (2) or more members of the Board all of whom are intended to be “non-employee directors” within the meaning of
Section 16 of the Securities Exchange Act of 1934 and the regulations promulgated thereunder and “outside directors” within the contemplation of Section 162(m) of the Code; provided, however, that, if at any time no
Compensation Committee or other Committee has been appointed or is eligible to act in the circumstances, the Plan shall be administered by the Board. As used herein, the term “Administrator” means the Board, the Compensation
Committee or any of the Board’s other Committees as shall be administering the Plan or any individual delegated authority to act as the Administrator in accordance with this Section 2. 
 The Administrator shall have plenary authority to grant Awards pursuant to the terms of the Plan to Eligible Individuals. Participation shall be limited to such persons
as are selected by the Administrator. Subject to Section 409A of the Code, Awards may be granted as alternatives to, in exchange or substitution for, or replacement of, awards outstanding under the Plan or any other plan or arrangement of the
Company or a Subsidiary (including, subject to the requirements under the Plan, a plan or arrangement of a business or entity, all or a portion of which is acquired by the Company or a Subsidiary). The provisions of Awards need not be the same with
respect to each Participant. 
 Among other things, the Administrator shall have the authority, subject to the terms of the Plan: 
  

	 	(a)	to select the Eligible Individuals to whom Awards may from time to time be granted; 

	 	(b)	to determine whether and to what extent Stock Options, Stock Awards or any combination thereof are to be granted hereunder; 

  

	 	(c)	to determine the number of shares of Stock to be covered by each Award granted hereunder; 

  

	 	(d)	to approve forms of agreement for use under the Plan; 

  

	 	(e)	to determine the terms and conditions, not inconsistent with the terms of this Plan, of any Award granted hereunder (including, but not limited to, the option price, any vesting
restriction or limitation, any vesting acceleration or waiver of forfeiture, and any right of repurchase, right of first refusal or other transfer restriction regarding any Award and the shares of Stock relating thereto, based on such factors or
criteria as the Administrator shall determine); 

  

	 	(f)	subject to Section 8(a), to modify, amend or adjust the terms and conditions of any Award, at any time or from time to time, including, but not limited to, with respect
to (i) performance goals and targets applicable to performance based Awards pursuant to the terms of the Plan and (ii) extension of the post-termination exercisability period of Stock Options; 

  

	 	(g)	to determine the Fair Market Value; and 

  

	 	(h)	to determine the type and amount of consideration to be received by the Company for any Stock Award issued under Section 5. 

 The Administrator shall have the authority to adopt, alter and repeal such administrative rules, guidelines and practices governing the Plan as it shall, from time to
time, deem advisable, to interpret the terms and provisions of the Plan and any Award issued under the Plan (and any agreement relating thereto) and to otherwise supervise the administration of the Plan. 
 In order to assure the viability of Awards granted to Participants employed in foreign countries who are not subject to U.S. tax law, the Administrator may provide for
such special terms as it may consider necessary or appropriate to accommodate differences in local law, tax policy, or custom. Moreover, the Administrator may approve such supplements to, or amendments, restatements, or alternative versions of, the
Plan as it may consider necessary or appropriate for such purposes without thereby affecting the terms of the Plan as in effect for any other purpose; provided, however, that no such supplements, amendments, restatements, or alternative
versions shall increase the share limitations contained in Section 3 of the Plan. 
 Except to the extent prohibited by applicable law, the
Administrator may allocate all or any portion of its responsibilities and powers to any one or more of its members and may delegate all 

  

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or any portion of its responsibilities and powers to any other person or persons selected by it. Any such allocation or delegation may be revoked by the
Administrator at any time. The Administrator may authorize any one or more of their members or any officer of the Company to execute and deliver documents on behalf of the Administrator. 
 Any determination made by the Administrator or pursuant to delegated authority pursuant to the provisions of the Plan with respect to any Award shall be made in the sole discretion of the Administrator or such
delegate at the time of the grant of the Award or, unless in contravention of any express term of the Plan, at any time thereafter. All decisions made by the Administrator or any appropriately delegated officer pursuant to the provisions of the Plan
shall be final and binding on all persons, including the Company and Participants. 
 No member of the Administrator, and no officer of the Company, shall be
liable for any action taken or omitted to be taken by such individual or by any other member of the Administrator or officer of the Company in connection with the performance of duties under this Plan, except for such individual’s own willful
misconduct or as expressly provided by law. 
  

	3.	STOCK SUBJECT TO PLAN. 

 Subject to adjustment as provided in
this Section 3, the aggregate number of shares of Stock which may be delivered under the Plan shall not exceed eight million (8,000,000) shares. 
 To the extent any shares of Stock covered by an Award are not delivered to a Participant or beneficiary thereof because the Award expires, is forfeited, lapses without exercise, canceled or otherwise terminated, or the shares of Stock are
not delivered because the Award is settled in cash or are used to satisfy the applicable tax withholding obligation, such shares shall not be deemed to have been delivered for purposes of determining the maximum number of shares of Stock available
for delivery under the Plan with respect to, and shall be available for, future grants of Awards. 
 Subject to adjustment as provided in this
Section 3, the maximum number of shares that may be covered by Stock Options and Stock Awards, in the aggregate, granted to any one Participant during any calendar year shall be one million five hundred thousand (1,500,000) shares.

 In the event of any Company stock dividend, special cash dividend, stock split, combination or exchange of shares, recapitalization or other change in the
capital structure of the Company, corporate separation or division of the Company (including, but not limited to, a split-up, spin-off, split-off or other distribution to Company stockholders, other than a normal cash dividend), sale by the Company
of all or a substantial portion of its assets (measured on either a stand-alone or consolidated basis), reorganization, rights offering, partial or complete liquidation, merger or consolidation in which the Company is the surviving corporation, or
any other corporate transaction, Company share offering or other event involving the Company and having an effect similar to any of the foregoing, the Administrator may make such substitution or adjustments in 

  

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the (a) number and kind of shares that may be delivered under the Plan, (b) additional maximums imposed in the immediately preceding paragraph,
(c) number and kind of shares subject to outstanding Awards, (d) exercise price of outstanding Stock Options and (e) other characteristics or terms of the Awards as it may determine appropriate in its sole discretion to equitably
reflect such corporate transaction, share offering or other event; provided, however, that the number of shares subject to any Award shall always be a whole number and any fractional share resulting from an adjustment or substitution
provided for hereunder shall be rounded up to the nearest whole share. 
 In the event of the dissolution or liquidation of the Company, or a merger,
reorganization or consolidation in which the Company is not the surviving corporation, then, except as otherwise provided herein and/or in the discretion of the Administrator, each Stock Option, to the extent not theretofore exercised, shall
terminate forthwith. 
 Notwithstanding the foregoing, no adjustment shall be made pursuant to this Section 3 to the extent that such adjustment
would violate Section 409A of the Code. 
  

	4.	STOCK OPTIONS. 

 Stock Options may be granted alone or in
addition to other Awards granted under the Plan and may be of two types: Incentive Stock Options and Non-Qualified Stock Options. Any Stock Option granted under the Plan shall be in such form as the Administrator may from time to time approve.

 The Administrator shall have the authority to grant any Participant Incentive Stock Options, Non-Qualified Stock Options or both types of Stock Options.
Incentive Stock Options may be granted only to employees of the Company and its subsidiaries (within the meaning of Section 424(f) of the Code). To the extent that any Stock Option is not designated as an Incentive Stock Option or, even if so
designated, does not qualify as an Incentive Stock Option, it shall constitute a Non-Qualified Stock Option. Incentive Stock Options may be granted only within ten (10) years from the date the Plan is adopted, or the date the Plan is approved
by the Company’s stockholders, whichever is earlier. 
 Stock Options shall be evidenced by option agreements, each in a form approved by the
Administrator. An option agreement shall indicate on its face whether it is intended to be an agreement for an Incentive Stock Option or a Non-Qualified Stock Option. 
 Anything in the Plan to the contrary notwithstanding, no term of the Plan relating to Incentive Stock Options shall be interpreted, amended or altered, nor shall any discretion or authority granted under the Plan be
exercised, so as to disqualify the Plan under Section 422 of the Code or, without the consent of the Optionee affected, to disqualify any Incentive Stock Option under Section 422 of the Code. 
  

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 To the extent that the aggregate Fair Market Value of Stock with respect to which Incentive Stock Options are exercisable
for the first time by a Participant during any calendar year (under all plans of the Company and its subsidiaries within the meaning of Section 424(f) of the Code) exceeds $100,000, such Stock Options shall be treated as Non-Qualified Stock
Options. 
 Stock Options granted under this Section 4 shall be subject to the following terms and conditions and shall contain such additional
terms and conditions as the Administrator shall deem desirable: 
  

	 	(a)	Exercise Price. The exercise price per share of Stock purchasable under a Stock Option shall be determined by the Administrator at the time of grant; provided,
however, that the exercise price per share shall be not less than the Fair Market Value per share on the date the Stock Option is granted, or in the case of an Incentive Stock Option granted to an individual who is a Ten Percent Holder, not
less than 110% of such Fair Market Value per share on the date the Stock Option is granted. 

  

	 	(b)	Option Term. Except as otherwise provided in the applicable option agreement, no Stock Option shall be exercisable more than ten (10) years after the date that the Stock
Option is granted; provided that under no circumstances shall an Incentive Stock Option be exercisable more than ten (10) years (or five (5) years in the case of an individual who is a Ten Percent Holder) after the date the
Incentive Stock Option is granted. 

  

	 	(c)	Vesting. Except as otherwise provided in the applicable option agreement, a Stock Option shall become vested and non-forfeitable with respect to one-third of the Stock
underlying such Stock Option on the first anniversary of the date of grant, with an additional one-twelfth of the Stock underlying such Stock Option becoming vested and non-forfeitable on each successive third month anniversary thereafter, so that
the remaining two-thirds of the Stock underlying the Stock Option shall become vested on the third anniversary of the date of grant; provided, in each case, that the Participant shall have continuously remained in the active employment of the
Company or an Affiliate. 

  

	 	(d)	Exercisability. Stock Options shall be exercisable to the extent vested; provided that the exercise of a Stock Option shall be subject to such additional terms
and conditions, performance requirements, restrictions, forfeiture provisions, contingencies and limitations, if any, as shall be determined by the Administrator and listed in the applicable option agreement. If any Stock Option is exercisable only
in installments, the Administrator may at any time waive such installment exercise provisions, in whole or in part, based on such factors as the Administrator may determine. In addition, the Administrator may at any time, in whole or in part,
accelerate the exercisability of any Stock Option. 

  

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	 	(e)	Method of Exercise. Stock Options may be exercised, in whole or in part, by giving written notice of exercise to the Company specifying the number of shares of Stock subject
to the Stock Option to be purchased. 

 The option price of any Stock Option shall be paid in full in cash (by certified or bank
check or such other instrument as the Company may accept) or, unless otherwise provided in the applicable option agreement, by one or more of the following: (i) in the form of shares of unrestricted and vested Stock already owned by the
Optionee, based on the Fair Market Value of the Stock on the date the Stock Option is exercised; (ii) by certifying ownership of shares of Stock owned by the Optionee to the satisfaction of the Administrator for later delivery to the Company as
specified by the Company; (iii) unless otherwise prohibited by law for either the Company or the Optionee, by irrevocably authorizing a third party to sell shares of Stock (or a sufficient portion of the shares) acquired upon exercise of the
Stock Option and remit to the Company a sufficient portion of the sale proceeds to pay the entire exercise price and any tax withholding resulting from such exercise; or (iv) by any combination of cash and/or any one or more of the methods
specified in clauses (i), (ii) and (iii). Notwithstanding the foregoing, a form of payment shall not be permitted to the extent it would cause the Company to recognize a compensation expense (or additional compensation expense) with respect to
the Stock Option for financial reporting purposes. 
 Unless otherwise determined by the Administrator, if payment of the option exercise
price of a Non-Qualified Stock Option is made in whole or in part in the form of stock that is subject to restrictions on transfer and/or forfeiture provisions (“Restricted Stock”), some or all of the Stock received upon such exercise
shall be subject to the same restrictions as such Restricted Stock. The number of shares of Stock received upon such exercise that shall be subject to such restrictions shall equal the number of shares of Restricted Stock used for payment of the
option exercise price. 
 No shares of Stock shall be issued upon exercise of a Stock Option until full payment therefor has been made. Upon
exercise of a Stock Option (or a portion thereof), the Company shall have a reasonable time to issue the Stock for which the Stock Option has been exercised, and the Optionee shall not be treated as a stockholder for any purposes whatsoever prior to
such issuance. No adjustment shall be made for cash dividends or other rights for which the record date is prior to the date such Stock is recorded as issued and transferred in the Company’s official stockholder records, except as otherwise
provided herein or in the applicable option agreement. 
  

	 	(f)	 Transferability of Stock Options. Except as otherwise provided in the applicable option agreement, a Non-Qualified Stock Option (i) shall be
transferable by the 

  

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Optionee to a Family Member of the Optionee, provided that (A) any such transfer shall be by gift with no consideration and (B) no
subsequent transfer of such Stock Option shall be permitted other than by will or the laws of descent and distribution, and (ii) shall not otherwise be transferable except by will or the laws of descent and distribution. An Incentive Stock
Option shall not be transferable except by will or the laws of descent and distribution. A Stock Option shall be exercisable, during the Optionee’s lifetime, only by the Optionee or by the guardian or legal representative of the Optionee, it
being understood that the terms “holder” and “Optionee” include the guardian and legal representative of the Optionee named in the applicable option agreement and any person to whom the Stock Option is transferred
(X) pursuant to the first sentence of this Section 4(f) or pursuant to the applicable option agreement or (Y) by will or the laws of descent and distribution. Notwithstanding the foregoing, references herein to the termination
of an Optionee’s employment or provision of services shall mean the termination of employment or provision of services of the person to whom the Stock Option was originally granted. 

  

	 	(g)	Termination by Death. Except as otherwise provided in the applicable option agreement, if an Optionee’s employment or provision of services terminates by reason of
death, any Stock Option held by such Optionee shall (except to the extent that such Stock Option is a performance-based Award) be fully vested upon such death and may thereafter be exercised for a period of one year from the date of such death or
until the expiration of the stated term of such Stock Option, whichever period is shorter. 

  

	 	(h)	Termination by Reason of Disability. Except as otherwise provided in the applicable option agreement, if an Optionee’s employment or provision of services terminates by
reason of Disability, any Stock Option held by such Optionee shall (except to the extent that such Stock Option is a performance-based Award) be fully vested upon such termination of employment or provision of services and may thereafter be
exercised by the Optionee for a period of one year from the date of such termination of employment or provision of services or until the expiration of the stated term of such Stock Option, whichever period is shorter. 

  

	 	(i)	 Termination by Reason of Retirement. Except as otherwise provided in the applicable option agreement, if an Optionee’s employment or provision of
services terminates by reason of Retirement, any Stock Option held by such Optionee, to the extent it was exercisable at the time of termination, may thereafter be exercised by the Optionee for a period of six months from the date of such
termination of employment or provision of services or until the expiration of the stated term of such Stock Option, whichever period is shorter, and any Stock 

  

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Option that is unvested or unexercisable at the date of termination shall thereupon terminate. 

  

	 	(j)	Involuntary Termination Without Cause. Except as otherwise provided in the applicable option agreement, if an Optionee’s employment or provision of services terminates
involuntarily without Cause, and for reasons other than death, Disability or Retirement, any Stock Option held by such Optionee may thereafter be exercised, to the extent it was exercisable at the time of termination, for a period of three months
from the date of such termination of employment or provision of services or until the expiration of the stated term of such Stock Option, whichever period is shorter, and any Stock Option that is unvested or unexercisable at the date of termination
shall thereupon terminate. 

  

	 	(k)	Involuntary Termination for Cause. Except as otherwise provided in the applicable option agreement, if an Optionee’s employment or provision of services terminates
involuntarily for Cause, all Stock Options held by such Optionee, whether or not then vested and exercisable, shall thereupon terminate. 

  

	 	(l)	Other Termination. Except as otherwise provided in the applicable option agreement, if an Optionee’s employment or provision of services is terminated by the Optionee
for any reason other than death, Disability or Retirement, any Stock Option held by such Optionee may thereafter be exercised, to the extent it was exercisable at the time of termination, for a period of 1 month from the date of such termination of
employment or provision of services or until the expiration of the stated term of such Stock Option, whichever period is shorter, and any Stock Option that is unvested or unexercisable at the date of termination shall thereupon terminate.

  

	 	(m)	Notwithstanding the foregoing, to the extent permitted under Section 409A of the Code, the exercise period following a termination described in subsection (g), (h), (i),
(j) or (l) above shall be tolled for any applicable window/blackout period restrictions under the Company’s insider trading policy. 

  

	5.	STOCK AWARDS OTHER THAN OPTIONS. 

 Stock Awards may be
directly issued under the Plan (without any intervening options), subject to such terms, conditions, performance requirements, restrictions, forfeiture provisions, contingencies and limitations as shall be determined by the Administrator and set
forth in the applicable award agreement. Subject to the provisions of this Section 5, Stock Awards may be issued which vest in one or more installments over the Participant’s period of employment and/or other service to the Company
and/or upon the attainment of specified performance objectives, and/or the Company may issue Stock Awards which entitle the Participant to receive a specified number of vested shares of Stock upon the attainment of one or more performance goals
and/or 

  

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service requirements established by the Administrator. Except as set forth in the applicable award agreement, a Stock Award shall become vested and
nonforfeitable with respect to one-third of the shares of Stock underlying such Stock Award on the first anniversary of the date of grant, with an additional one-twelfth becoming vested and non-forfeitable on each successive third month anniversary
thereafter, so that the remaining two-thirds of the Stock underlying the stock award will become vested on the third anniversary of the date of grant. 
 Shares representing a Stock Award shall be evidenced in such manner as the Administrator may deem appropriate, including book-entry registration or issuance of one or more certificates (which may bear appropriate legends referring to the
terms, conditions and restrictions applicable to such Award). The Administrator may require that any such certificates be held in custody by the Company until any restrictions thereon shall have lapsed and that the Participant deliver a stock power,
endorsed in blank, relating to the Stock covered by such Award. 
 A Stock Award may be issued in exchange for any consideration which the Administrator may
deem appropriate in each individual instance, including, without limitation: 
  

	 	(a)	cash or cash equivalents; 

  

	 	(b)	past services rendered to the Company or any Affiliate; or 

  

	 	(c)	future services to be rendered to the Company or any Affiliate (provided that, in such case, the par value of the stock subject to such Stock Award shall be paid in
cash or cash equivalents, unless the Administrator provides otherwise). 

 A Participant, at his or her option, will be entitled to make the
election permitted under Section 83(b) of the Code, to include in gross income in the taxable year in which the Stock Award are transferred to him or her, the fair market value of such shares at the time of transfer, notwithstanding that such
shares are subject to a substantial risk of forfeiture within the meaning of the Code, or he or she may elect to include in gross income the Fair Market Value of the Stock Award as of the date or date on which such restrictions lapse.
Notwithstanding the foregoing, the Administrator shall adopt, from time to time, such rules with respect to the return of executed award agreements as it deems appropriate and failure by a Participant to comply with such rules shall, without
limitation, terminate the grant of such Stock Award to such Participant and/or cause the forfeiture of any Stock Award as to which restrictions have not yet lapsed. 
  

	6.	PERFORMANCE AWARDS. 

  

	 	(a)	 Performance Conditions. The right of a Participant to exercise or receive a grant or settlement of any Award, and its timing, may be subject to performance
conditions specified by the Administrator at the time of grant (except as provided 

  

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in this Section 6). The Administrator may use business criteria and other measures of performance it deems appropriate in establishing any
performance conditions, and may exercise its discretion to reduce or increase amounts payable under any Award subject to performance conditions, except as limited under Section 6(b) hereof in the case of a Performance Award intended to
qualify under Section 162(m) of the Code. 

  

	 	(b)	Performance Awards Granted to Designated Covered Employees. If the Administrator determines that a Performance Award to be granted to a person the Administrator regards as
likely to be a Covered Employee should qualify as “performance-based compensation” for purposes of Section 162(m) of the Code, the grant and/or settlement of such Performance Award shall be contingent upon achievement of
pre-established performance goals and other terms set forth in this Section 6(b) 

  

	 	(i)	Performance Goals Generally. The performance goals for such Performance Awards shall consist of one or more business criteria and a targeted level or levels of performance
with respect to such criteria, as specified by the Administrator consistent with this Section 6(b). Performance goals shall be objective and shall otherwise meet the requirements of Section 162(m) of the Code, including the
requirement that the level or levels of performance targeted by the Administrator result in the performance goals being “substantially uncertain.” The Administrator may determine that more than one performance goal must be achieved as a
condition to settlement of such Performance Awards. Performance goals may differ for Performance Awards granted to any one Participant or to different Participants. 

  

	 	(ii)	Business Criteria. One or more business criteria for the Company, on a consolidated basis, and/or for specified Subsidiaries or business units of the Company (except with
respect to the total stockholder return and earnings per share criteria), shall be used by the Administrator in establishing performance goals for such Performance Awards and set forth in the applicable Performance Award Agreement.

  

	 	(iii)	Performance Period: Timing For Establishing Performance Goals. Achievement of performance goals in respect of such Performance Awards shall be measured over such duration as
may be specified by the Administrator. Performance goals shall be established on or before the dates that are required or permitted for “performance-based compensation” under Section 162(m) of the Code. 

  

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	 	(iv)	Settlement of Performance Awards; Other Terms. Settlement of Performance Awards may be in cash or Stock, or other Awards, or other property, in the discretion of the
Administrator. The Administrator may, in its discretion, reduce the amount of a settlement otherwise to be made in connection with such Performance Awards, but may not exercise discretion to increase any such amount payable in respect of a
Performance Award subject to this Section 6(b). The Administrator shall specify the circumstances in which such Performance Awards shall be forfeited or paid in the event of a termination of employment at least six months prior to the
end of a performance period or settlement of Performance Awards, and other terms relating to such Performance Awards. 

  

	7.	CHANGE IN CONTROL PROVISIONS. 

  

	 	(a)	Impact of Event. Notwithstanding any other provision of the Plan to the contrary, in the event of a Change in Control: 

  

	 	(i)	The vesting and exercisability of any Stock Options outstanding as of the date such Change in Control is determined to have occurred and not then vested and exercisable shall become
fully vested and exercisable; 

  

	 	(ii)	Any restrictions applicable to any outstanding Stock Awards shall lapse and the Stock relating to such Awards shall become free of all restrictions and fully vested and
transferable; and 

  

	 	(iii)	Outstanding Awards shall, provided that no material modification of the Award or any liability results under Section 409A of the Code, be subject to any agreement of
acquisition, merger or reorganization that effects such Change in Control and that provides for: 

  

	 	(A)	The continuation of the outstanding Awards by the Company, if the Company is a surviving corporation; 

  

	 	(B)	The assumption of the outstanding Awards by the surviving corporation or its parent or subsidiary; 

  

	 	(C)	The substitution by the surviving corporation or its parent or subsidiary of equivalent awards for the outstanding Awards; or 

  

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	 	(D)	Settlement of each share of Stock subject to an outstanding Award for the Change in Control Price (less, to the extent applicable, the per share exercise price), or, if the per
share exercise price equals or exceeds the Change in Control Price, the outstanding Award shall terminate and be canceled. 

  

	 	(b)	Definition of Change in Control. 

  

	 	(i)	For purposes of the Plan, a “Change in Control” shall occur or be deemed to have occurred only if any of the following events occur: 

  

	 	(A)	The acquisition, directly or indirectly, by any person or group (as those terms are defined in Sections 3(a)(9), 13(d) and 14(d) of the Exchange Act and the rules thereunder) of
beneficial ownership (as determined pursuant to Rule 13d-3 under the Exchange Act) of securities entitled to vote generally in the election of directors (voting securities) of the Company that represent 66-2/3% or more of the combined voting power
of the Company’s then outstanding voting securities, other than: 

  

	 	(1)	An acquisition by a trustee or other fiduciary holding securities under any employee benefit plan (or related trust) sponsored or maintained by the Company or any person controlled
by the Company or by any employee benefit plan (or related trust) sponsored or maintained by the Company or any person controlled by the Company; or 

  

	 	(2)	An acquisition of voting securities by the Company or a corporation owned, directly or indirectly by all of the stockholders of the Company in substantially the same proportions as
their ownership of the stock of the Company; or 

  

	 	(3)	An acquisition of voting securities pursuant to a transaction described in clause (C) below that would not be a Change in Control under clause (C); 

 Notwithstanding the foregoing, the following event shall not constitute an acquisition by any person or group for purposes of this
subsection (a): an acquisition of the Company’s securities by the Company which causes the Company’s voting securities beneficially owned by a person or group to represent 66-2/3% or more of the combined voting power of the Company’s
then outstanding voting securities; 

  

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provided, however, that if a person or group shall become the beneficial owner of 66-2/3% or more of the combined voting power of the Company’s
then outstanding voting securities by reason of share acquisitions by the Company as described above and shall, after such share acquisitions by the Company, become the beneficial owner of any additional voting securities of the Company, then such
acquisition shall constitute a Change in Control; or 
  

	 	(B)	The consummation by the Company (whether directly involving the Company or indirectly involving the Company through one or more intermediaries) of (x) a merger, consolidation,
reorganization, or business combination or (y) a sale or other disposition of all or substantially all of the Company’s assets or (z) the acquisition of assets or stock of another entity, in each case other than a transaction:

  

	 	(1)	Which results in the Company’s voting securities outstanding immediately before the transaction continuing to represent (either by the remaining outstanding or by being
converted into voting securities of the Company or the person that, as a result of the transaction, controls, directly or indirectly, the Company or owns, directly or indirectly, all or substantially all of the Company’s assets or otherwise
succeeds to the business of the Company (the Company or such person, the “Successor Entity”)) directly or indirectly, at least a majority of the combined voting power of the Successor Entity’s outstanding voting securities
immediately after the transaction; and 

  

	 	(2)	After which no person or group beneficially owns voting securities representing 66-2/3% or more of the combined voting power of the Successor Entity; provided, however, that
no person or group shall be treated for purposes of this clause (2) as beneficially owning 66-2/3% or more of combined voting power of the Successor Entity solely as a result of the voting power held in the Company prior to the consummation of
the transaction; or 

  

	 	(C)	The Company’s stockholders approve a liquidation or dissolution of the Company. 

 The Committee shall have full and final authority, which shall be exercised in its discretion, to determine conclusively whether a Change in Control of the Company has occurred pursuant to the above definition, and
the date of the occurrence of such Change in Control and any incidental matters relating thereto. 
  

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	 	(ii)	For purposes of Section 7(b), stock ownership is determined under Section 409A of the Code. 

  

	 	(c)	Change in Control Price. For purposes of the Plan, “Change in Control Price” means the Fair Market Value (which may be the amount of consideration per share
of Stock received by the holder of Stock in connection with the Change in Control transaction or, in the case of a tender or exchange offer, the highest price per share of Stock paid in such tender or exchange offer, in each case, as determined by
the Administrator in accordance with Section 9(n) hereunder) of a share of Stock on the date of a Change in Control. To the extent that the consideration paid in any such transaction described above consists all or in part of securities or
other non-cash consideration, the value of such securities or other non-cash consideration shall be determined in the sole discretion of the Board. The Participant shall receive the same form of consideration as holders of common stock, subject to
the same restrictions and limitations and indemnification obligations as the holders of common stock and will execute any and all documents required by the Administrator to evidence the same. 

  

	8.	MISCELLANEOUS. 

  

	 	(a)	Amendment. The Board may at any time terminate, amend, alter, or discontinue the Plan, but no amendment, alteration or discontinuation shall be made which would adversely
affect the rights of a Participant under an Award theretofore granted without the Participant’s consent, except such an amendment (i) made to avoid an expense charge to the Company or an Affiliate under applicable law or regulation,
(ii) made to permit the Company or an Affiliate a deduction under the Code or (iii) made to avoid the violation of Section 409A of the Code. No such amendment or alteration shall be made without the approval of a majority vote of the
Company’s shareholders, present in person or by proxy at any special or annual meeting of the shareholders to the extent such approval is required by law, agreement or the rules of any stock exchange or market on which the Stock is listed.

 The Administrator may amend the terms of any Stock Option or other Award theretofore granted, prospectively or retroactively,
but except as provided in Section 3 hereof no such amendment shall adversely affect the rights of a Participant without the Participant’s consent. 
  

	 	(b)	 Unfunded Status of Plan. It is intended that this Plan be an “unfunded” plan for incentive and deferred compensation. The Administrator may
authorize the 

  

 14 

	 	 
creation of trusts or other arrangements to meet the obligations created under this Plan to deliver Stock or make payments, provided that,
unless the Administrator otherwise determines, the existence of such trusts or other arrangements is consistent with the “unfunded” status of this Plan. 

  

	 	(c)	General Provisions. 

  

	 	(i)	Unless the shares to be issued in connection with an Award are registered prior to the issuance thereof under the Securities Act of 1933, as amended, the Administrator may require
each person purchasing or receiving shares pursuant to an Award to represent to and agree with the Company in writing that such person is acquiring the shares for his or her own account as an investment without a view to or for sale in connection
with, the distribution thereof. The certificates for such shares may include any legend which the Administrator deems appropriate to reflect any restrictions on transfer. 

 All certificates for shares of Stock or other securities delivered under the Plan shall be subject to such stock transfer orders and other restrictions
as the Administrator may deem advisable under the rules, regulations and other requirements of the Commission, any stock exchange or market on which the Stock is then listed and any applicable Federal or state securities law, and the Administrator
may cause a legend or legends to be put on any such certificates to make appropriate reference to such restrictions. 
  

	 	(ii)	Nothing contained in the Plan shall prevent the Company or any Affiliate from adopting other or additional compensation arrangements for its employees. 

  

	 	(iii)	The adoption of the Plan shall not confer upon any employee, director, associate, consultant or advisor any right to continued employment, directorship or service, nor shall it
interfere in any way with the right of the Company or any Subsidiary or Affiliate to terminate the employment or service of any employee, consultant or advisor at any time. 

  

	 	(iv)	 No later than the date as of which an amount first becomes includible in the gross income of the Participant for Federal income tax purposes with respect to any
Award under the Plan, the Participant shall pay to the Company, or make arrangements satisfactory to the Company regarding the payment of, any Federal, state, local or foreign taxes of any kind required by law to be withheld with respect to such
amount. Unless otherwise determined by the Administrator, withholding obligations may be settled with Stock, including Stock that is part of the Award that gives 

  

 15 

	 	 
rise to the withholding requirement. The obligations of the Company under the Plan shall be conditional on such payment or arrangements, and the Company, its
Subsidiaries and its Affiliates shall, to the extent permitted by law, have the right to deduct any such taxes from any payment otherwise due to the Participant. The Administrator may establish such procedures as it deems appropriate for the
settlement of withholding obligations with Stock. 

  

	 	(v)	The Administrator shall establish such procedures as it deems appropriate for a Participant to designate a beneficiary to whom any amounts payable in the event of the
Participant’s death are to be paid. In the event of the death of a Participant, a condition of exercising any Award shall be the delivery to the Company of such tax waivers and other documents as the Administrator shall determine.

  

	 	(vi)	Neither any Participant nor his or her legal representatives, legatees or distributees shall be or be deemed to be the holder of any share of Stock covered hereby unless and until a
certificate for such share has been issued. Upon payment of the purchase price thereof, a share shall be fully paid and non-assessable. 

  

	 	(vii)	The grant of an Award shall in no way affect the right of the Company to adjust, reclassify, reorganize or otherwise change its capital or business structure or to merge,
consolidate, dissolve, liquidate or sell or transfer all or any part of its business or assets, or issue bonds, debentures, preferred or prior preference stock ahead of or affecting the Stock, or take any other corporate act or proceeding whether of
a similar character or otherwise. 

  

	 	(viii)	 If any payment or right accruing to a Participant under this Plan (without the application of this Section 8(c)(viii)), either alone or together with
other payments or rights accruing to the Participant from the Company or an Affiliate (“Total Payments”) would constitute a “parachute payment” (as defined in Section 280G of the Code and regulations thereunder), such
payment or right shall be reduced to the largest amount or greatest right that will result in no portion of the amount payable or right accruing under this Plan being subject to an excise tax under Section 4999 of the Code or being disallowed
as a deduction under Section 280G of the Code; provided, however, that the foregoing shall not apply to the extent provided otherwise in an Award or in the event the Participant is party to an agreement with the Company or an
Affiliate that explicitly provides for an alternate treatment of payments or rights that would constitute “parachute payments.” The determination of whether any reduction in the rights or payments under this Plan is to apply shall be made
by the 

  

 16 

	 	 
Administrator in good faith after consultation with the Participant, and such determination shall be conclusive and binding on the Participant. The
Participant shall cooperate in good faith with the Administrator in making such determination and providing the necessary information for this purpose. The foregoing provisions of this Section 8(c)(viii) shall apply with respect to any
person only if, after reduction for any applicable Federal excise tax imposed by Section 4999 of the Code and Federal income tax imposed by the Code, the Total Payments accruing to such person would be less than the amount of the Total Payments
as reduced, if applicable, under the foregoing provisions of this Plan and after reduction for only Federal income taxes. 

  

	 	(ix)	To the extent that the Administrator determines that the restrictions imposed by the Plan preclude the achievement of the material purposes of the Awards in jurisdictions outside
the United States, the Administrator in its discretion may modify those restrictions as it determines to be necessary or appropriate to conform to applicable requirements or practices of jurisdictions outside of the United States.

  

	 	(x)	The headings contained in this Plan are for reference purposes only and shall not affect the meaning or interpretation of this Plan. 

  

	 	(xi)	If any provision of this Plan shall for any reason be held to be invalid or unenforceable, such invalidity or unenforceability shall not effect any other provision hereby, and this
Plan shall be construed as if such invalid or unenforceable provision were omitted. 

  

	 	(xii)	This Plan shall inure to the benefit of and be binding upon each successor and assign of the Company. All obligations imposed upon a Participant, and all rights granted to the
Company hereunder, shall be binding upon the Participant’s heirs, legal representatives and successors. 

  

	 	(xiii)	This Plan and each agreement granting an Award constitute the entire agreement with respect to the subject matter hereof and thereof, provided that in the event of any
inconsistency between this Plan and such agreement, the terms and conditions of the Plan shall control. 

  

	 	(xiv)	 In the event there is an effective registration statement under the Securities Act pursuant to which shares of Stock shall be offered for sale in an underwritten
offering, a Participant shall not, during the period requested by the underwriters managing the registered public offering, effect any public sale or distribution of shares of Stock received, directly or 

  

 17 

	 	 
indirectly, as an Award or pursuant to the exercise or settlement of an Award. 

  

	 	(xv)	None of the Company, an Affiliate or the Administrator shall have any duty or obligation to disclose affirmatively to a record or beneficial holder of Stock or an Award, and such
holder shall have no right to be advised of, any material information regarding the Company or any Affiliate at any time prior to, upon or in connection with receipt or the exercise of an Award or the Company’s purchase of Stock or an Award
from such holder in accordance with the terms hereof. 

  

	 	(xvi)	This Plan, and all Awards, agreements and actions hereunder, shall be governed by, and construed in accordance with, the laws of the state of Nevada. 

  

	 	(xvii)	No Award granted pursuant to this Plan is intended to constitute “deferred compensation” as defined in Section 409A of the Code, and the Plan and the terms of all
Awards shall be interpreted accordingly. If any provision of the Plan or an Award contravenes any regulations or Treasury guidance promulgated under Section 409A of the Code or could cause an Award to be subject to the penalties and interest
under Section 409A of the Code, such provision of the Plan or Award shall be modified to maintain, to the maximum extent practicable, the original intent of the applicable provision without violating the provisions of Section 409A of the
Code. 

  

	9.	DEFINITIONS. 

 For purposes of this Plan, the following terms
are defined as set forth below: 
  

	 	(a)	“Affiliate” means a corporation or other entity (i) controlled by the Company and which, in the case of grants of Stock Options would, together with the
Company, be classified as the “service recipient” (as defined in the regulations under Section 409A of the Code) with respect to an Eligible Individual, and (ii) is designated by the Administrator as such.

  

	 	(b)	“Award” means a Stock Option or Stock Award. 

  

	 	(c)	“Board” means the Board of Directors of the Company. 

  

	 	(d)	 “Cause” means (i) the commission by the Participant of any act or omission that would constitute a felony or any crime of moral turpitude
under Federal law or the law of the state or foreign law in which such action occurred, (ii) dishonesty, disloyalty, fraud, embezzlement, theft, disclosure of trade secrets or confidential 

  

 18 

	 	 
information or other acts or omissions that result in a breach of fiduciary or other material duty to the Company and/or a Subsidiary; or
(iii) continued reporting to work or working under the influence of alcohol, an illegal drug, an intoxicant or a controlled substance which renders Participant incapable of performing his or her material duties to the satisfaction of the
Company and/or its Subsidiaries. Notwithstanding the foregoing, if the Participant and the Company or the Affiliate have entered into an employment or services agreement which defines the term “Cause” (or a similar term), such
definition shall govern for purposes of determining whether such Participant has been terminated for Cause for purposes of this Plan. The determination of Cause shall be made by the Administrator, in its sole discretion.

  

	 	(e)	“Code” means the Internal Revenue Code of 1986, as amended from time to time, and any successor thereto. 

  

	 	(f)	“Commission” means the Securities and Exchange Commission or any successor agency. 

  

	 	(g)	“Committee” means a committee of Directors appointed by the Board to administer this Plan. Insofar as the Committee is responsible for granting Awards to
Participants hereunder, it shall consist solely of two or more directors, each of whom is a “non-employee director” within the meaning of Rule 16b-3, an “outside director” under Section 162(m) of the Code, an
“independent director” as defined by the Sarbanes-Oxley Act of 2002, and “independent” as defined by the rules of any stock exchange or market on which the Stock is listed. 

  

	 	(h)	“Covered Employee” means a person who is a “covered employee” within the meaning of Section 162(m) of the Code. 

  

	 	(i)	“Director” means a member of the Company’s Board. 

  

	 	(j)	 “Disability” means mental or physical illness that entitles the Participant to receive benefits under the long-term disability plan of the Company
or an Affiliate, or if the Participant is not covered by such a plan or the Participant is not an employee of the Company or an Affiliate, a mental or physical illness that renders a Participant totally and permanently incapable of performing the
Participant’s duties for the Company or an Affiliate; provided, however, that a Disability shall not qualify under this Plan if it is the result of (i) a willfully self-inflicted injury or willfully self-induced sickness; or
(ii) an injury or disease contracted, suffered or incurred while participating in a criminal offense. Notwithstanding the foregoing, if the Participant and the Company or an Affiliate have entered into an employment or services agreement which
defines the term “Disability” (or a similar term), such definition shall govern for purposes of 

  

 19 

	 	 
determining whether such Participant suffers a Disability for purposes of this Plan. The determination of Disability shall be made by the Administrator, in
its sole discretion. The determination of Disability for purposes of this Plan shall not be construed to be an admission of disability for any other purpose. 

  

	 	(k)	“Effective Date” means August 7, 2006. 

  

	 	(l)	“Eligible Individual” means any (i) officer, employee, associate or director of the Company or a Subsidiary or Affiliate, (ii) any consultant or advisor
providing services to the Company or a Subsidiary or Affiliate, or (iii) employees of (x) a corporation or other business enterprise which has been acquired by the Company or a Subsidiary, which, in the case of grants of Stock Options and
Stock Awards would, together with the Company and, if applicable, the Subsidiary, be classified as the “service recipient” (as defined in the regulations under Section 409A of the Code) with respect to such employees and (y) who
hold options with respect to the stock of such corporation which the Company has agreed to assume. 

  

	 	(m)	“Exchange Act” means the Securities Exchange Act of 1934, as amended from time to time, and any successor thereto. 

  

	 	(n)	 “Fair Market Value” means, as of any given date, the fair market value of the Stock, determined as follows: (i) if the Stock is listed on any
established stock exchange or a national market system, including without limitation, the Nasdaq National Market or the Nasdaq SmallCap Market, its fair market value on such date shall be the reported closing selling price for the Stock on the
principal securities exchange or national market system on which the Stock is at such date listed for trading; provided that if there are no sales of Stock on that date, then the reported closing selling price for the Stock on the next
preceding date shall be determinative of fair market value; or (ii) if the Stock is listed on the OTC Electronic Bulletin Board, its fair market value on such date shall be the closing selling price on such date for the Stock as reported on the
OTC Electronic Bulletin Board; provided that if there are no sales of the Stock on that date, then the reported closing selling price for the Stock on the next preceding date for which such closing selling price is quoted shall be
determinative of fair market value; or, (iii) if the Stock is not traded on the OTC Electronic Bulletin Board, an exchange, or a national market system, or notwithstanding (i) and (ii) above, if a determination of Fair Market Value
under (i) or (ii) above would violate the rules under Section 409A of the Code and the regulations thereunder with respect to the determination of fair market value, Fair Market Value of the Stock on such date shall be determined in
good faith by the Administrator in accordance with Section 409A of the Code and the regulations issued thereunder, and such determination shall be conclusive and binding on all persons. In the event of a Change in Control, notwithstanding the
foregoing provisions of this Section 9(n), Fair 

  

 20 

	 	 
Market Value of the Stock in connection with such Change in Control transaction shall be determined in good faith by the Administrator in accordance with
Section 409A of the Code and the regulations issued thereunder, and such determination shall be conclusive and binding on all persons. 

  

	 	(o)	“Family Member” means any child, stepchild, grandchild, parent, stepparent, grandparent, spouse, former spouse, sibling, niece, nephew, mother-in-law,
father-in-law, son-in-law, daughter-in-law, brother-in-law or sister-in-law of a Participant (including adoptive relationships); any person sharing the Participant’s household (other than a tenant or employee); any trust in which the
Participant and any of these persons have all of the beneficial interest; any foundation in which the Participant and any of these persons control the management of the assets; any corporation, partnership, limited liability company or other entity
in which the Participant and any of these other persons are the direct and beneficial owners of all of the equity interests (provided the Participant and these other persons agree in writing to remain the direct and beneficial owners of all
such equity interests); and any personal representative of the Participant upon the Participant’s death for purposes of administration of the Participant’s estate or upon the Participant’s incompetency for purposes of the protection
and management of the assets of the Participant. 

  

	 	(p)	“Incentive Stock Option” means any Stock Option intended to be and designated as an “incentive stock option” within the meaning of Section 422 of the
Code. 

  

	 	(q)	“Non-Qualified Stock Option” means any Stock Option that is not an Incentive Stock Option. 

  

	 	(r)	“Optionee” means a person who holds a Stock Option. 

  

	 	(s)	“Participant” means a person granted an Award. 

  

	 	(t)	“Performance Award” means a right, granted to a Participant under Section 6, to receive Awards based upon performance criteria specified by the
Administrator. 

  

	 	(u)	 “Representative” means (i) the person or entity acting as the executor or administrator of a Participant’s estate pursuant to the last
will and testament of a Participant or pursuant to the laws of the jurisdiction in which the Participant had his or her primary residence at the date of the Participant’s death; (ii) the person or entity acting as the guardian or temporary
guardian of a Participant; (iii) the person or entity which is the beneficiary of the Participant upon or following the Participant’s death; or (iv) any person to whom a Stock Option has been transferred with the permission of the
Administrator or by operation of law; 

  

 21 

	 	 
provided that only one of the foregoing shall be the Representative at any point in time as determined under applicable law and recognized by
the Administrator. 

  

	 	(v)	“Retirement” means termination of employment or provision of services without Cause, death or Disability on or after age 65 with 5 years of service.

  

	 	(w)	“Stock” means the common stock, par value $.01 per share, of the Company. 

  

	 	(x)	“Stock Award” means an Award, other than a Stock Option or Stock Appreciation Right, made in Stock or denominated in shares of Stock. 

  

	 	(y)	“Stock Option” means an option granted under Section 4. 

  

	 	(z)	“Subsidiary” means any company during any period in which it is a “subsidiary corporation” (as such term is defined in Section 424(f) of the Code)
with respect to the Company. 

  

	 	(aa)	“Ten Percent Holder” means an individual who owns, or is deemed to own, stock possessing more than 10% of the total combined voting power of all classes of stock of
the Company or of any parent or subsidiary corporation of the Company, determined pursuant to the rules applicable to Section 422(b)(6) of the Code. 

 In addition, certain other terms used herein have the definitions given to them in the places they are first used. 
  

 22Termination of Agreement and Releases

 Exhibit 10.2 
 TERMINATION OF AGREEMENT AND RELEASES 
 AGREEMENT dated as of November 6, 2006, between SUPRATEK
PHARMA, INC. (“SPI”), on the one hand, and AVANTOGEN ONCOLOGY, INC., formerly known as Innovate Oncology, Inc. (“AOI”), and GARDANT PHARMACEUTICALS INC., formerly known as Bioaccelerate Holdings Inc.
(“GDT”), severally, on the other hand. 
 SPI and GDT are the parties to the License and Co-Marketing Agreement effective
July 15, 2004 (the “Licensing Agreement”), pursuant to which SPI licensed GDT to develop and commercialize products comprising or utilizing SPI’s proprietary SP1010-O for the treatment of cancer in humans. GDT subsequently
assigned, GDT’s rights and obligations under the Licensing Agreement to AOI, and AOI accepted such assignment. 
 SPI has requested that
AOI and GDT agree to terminate the Licensing Agreement, with the result that all rights granted thereunder to GDT and to AOI as GDT’s assignee would revert to SPI, and AOI (on the basis of a recent strategic review suggesting prioritization of
its lead clinical development program, RP101) and GDT are amenable to so doing, in each case, pursuant to the terms and subject to the conditions of this Agreement. 
 Accordingly, the parties hereto hereby agree as follows: 
 1. The License Agreement is hereby terminated
effective as of the date hereof and shall no longer have any force or effect, and all rights granted under the License Agreement to GDT and to AOI as GDT’s assignee hereby revert to SPI effective as of the date hereof. 
 2. Each party hereto (a “Releasing Party”), on behalf of itself, its predecessors, and each of its present and former officers,
employees, directors, shareholders, parents, subsidiaries, alter egos, affiliates, partners, agents, attorneys, accountants, successors and assigns, hereby fully and forever releases and discharges each of the other parties, its predecessors, and
each of its present and former officers, employees, directors, shareholders, parents, subsidiaries, alter egos, affiliates, partners, agents, attorneys, accountants, successors and assigns (each, a “Released Party”), from any and
all claims, demands, liens, actions, agreements, suits, causes of action, obligations, controversies, debts, costs, attorneys’ fees, expenses, damages, judgments, orders and liabilities of whatever kind or nature, at law, in equity or
otherwise, whether now known or suspected, which have existed or may have existed or which do exist or which hereafter can or may exist, based on any facts events or omissions occurring from any time on or prior to execution of this Agreement, which
arise out of, concern, pertain or relate in any way to the License Agreement (the “Released Claims”). For more certainty, the “Released Claims” shall not include any claim arising out of, concerning, pertaining or related
in any way to the Form of Securities Purchase Agreement between SPI and Bioaccelerate Holdings Inc., dated March 9, 2005, as amended. 
 Each Releasing Party acknowledges that there is a possibility that subsequent to the execution of this Agreement, it will discover facts or incur or suffer claims which were unknown or unsuspected at the time this Agreement was executed and
which, if known by it at 

 
that time, may have materially affected its decision to execute this Agreement and that, by reason of this Agreement, it is assuming any risk of such unknown
facts and such unknown and unsuspected claims. Such party has been advised of the existence of Section 1542 of the California Civil Code (“Section 1543”), which provides: 
 A GENERAL RELEASE DOES NOT EXTEND TO CLAIMS WHICH THE CREDITOR DOES NOT KNOW OR SUSPECT TO EXIST IN HIS OR HER FAVOR AT THE TIME OF
EXECUTING THE RELEASE, WHICH IF KNOWN BY HIM OR HER MUST HAVE MATERIALLY AFFECTED HIS OR HER SETTLEMENT WITH THE DEBTOR. 
 Notwithstanding
the foregoing, this Agreement shall constitute a full release in accordance with its terms. Each Releasing Party knowingly and voluntarily waives the provisions of Section 1542, as well as any other statute, law or rule of similar effect. In
connection with such waiver and relinquishment, such Releasing Party acknowledges that it is aware that it may hereafter discover claims presently unknown or unsuspected or facts in addition to or different from those which it now knows or believes
to be true, with respect to the matters released herein. Nevertheless, it is the intention of the Releasing Party, through this Agreement, fully and finally to settle and release all such matters, and all claims relative thereto, which do now exist
or have existed between and among the parties hereto. The Releasing Party hereby acknowledges that it understands and acknowledges the significance and consequence of this release and of this specific waiver of Section 1542 and other such laws.

 Each Released Party will forever refrain and forbear from commencing, instituting or prosecuting any lawsuit, action or other proceeding
of any kind whatsoever, by way of action, defense, set-off, cross-complaint or counterclaim, against the Released Parties based on, arising out of or in connection with any Released Claim, except for an action commenced to enforce any rights
conferred in this Agreement. In the event of any violation of its undertaking pursuant to this paragraph by a Releasing Party, this Agreement will be subject to termination at the election of the affected Released Party. 
 3. Each Releasing Party represents and warrants: 
 (a) that no other party, nor any agent or attorney of any other party, has made any promise, representation or warranty whatsoever, express or implied, not contained herein concerning the subject matter hereof, to
induce it to execute this Agreement; 
 (b) that the person executing this Agreement in a representative capacity on its
behalf is authorized and empowered to do so; 
 (c) that it has read this Agreement and understands the contents hereof and
has made such an investigation of the facts pertinent to this Agreement and of all the matters pertaining hereto as it deems necessary; and 

 (d) that it has been represented by legal counsel of its own choice throughout all
negotiations which preceded execution of this Agreement and has executed this Agreement with the consent and advice of such counsel. 
 4.
Each Releasing Party further represents and warrants that it has not assigned or transferred any Released Claim that the Releasing Party has or may have against any Released Party, and agrees to indemnify and hold the Released Parties harmless from
any liabilities, claims demands, damages, costs, expenses and attorneys’ fees incurred by any of them as a result of any person asserting any such assignment or transfer. 
 5. Nothing in this Agreement will be construed as an express or implied admission or acknowledgment by any party hereto of any liability to any other
party or to any other person, all such liability being expressly denied. The parties hereto agree that this Agreement is the result of a compromise within the meaning of California Evidence Code Sections 1152 and 1154. 
 6. Each party hereto will upon request by another party, without charge or other consideration, execute such additional documentation and cooperate in
such further proceedings as may become necessary to effectuate the terms of this Agreement. 
 7. This Agreement constitutes the entire
agreement and understanding of the parties hereto concerning the subject matter hereof and supercedes and replaces any and all prior negotiations, proposed agreements and agreements, oral or written, relating thereto. No covenants, agreements,
representations or warranties of any kind whatsoever have been made by any party, except as specifically set forth in his Agreement. 
 8.
Any and all questions with respect to the construction of this Agreement and the rights and liabilities of the parties hereto will be governed by the laws of, and will be submitted and resolved by a court of competent jurisdiction sitting in, the
State stipulated by the parties thereto in the Licensing Agreement. 
 9. This Agreement may be executed in any number of counterparts, and
delivered via facsimile transmission, each of which will be deemed an original, but all of which together will constitute one and same instrument. 
 10. If any provision of this Agreement is adjudicated to be unenforceable or invalid for any reason, that part will be deemed to be severed from the balance of this Agreement, which will in no way be affected or impaired, unless the severed
portion was essential to the intended purpose of this Agreement, in which case, the party who was to receive the benefit of the severed portion has the option to void this Agreement. 
 11. A party hereto, including any Released Party, to the extent such party is the prevailing party in such action, will be entitled to recover its
reasonable attorneys’ fees, court costs and other fees, costs and disbursements in any action brought to enforce or interpret this Agreement. 

 12. This Agreement will bind and inure to the benefit of the parties hereto, including Released Parties,
and their respective successors, assigns, heirs, administrators, executors and conservators. 
 13. This Agreement will be construed
neutrally, and not applied more strictly against one party than another. This Agreement is null and void and shall have no effect unless it is signed by all three parties hereto. 
 IN WITNESS WHEREOF, the parties hereto have hereunto set their hands, all as of the date first hereinabove written. 
  

									
	SUPRATEK PHARMA, INC.	 		 	AVANTOGEN ONCOLOGY, INC.
					
	By:	 	/s/ Oleg Romar	 		 	By:	 	/s/ Christopher Nowers
		 	Oleg Romar	 		 		 	Christopher Nowers
		 	President and Chief Executive Officer	 		 		 	Chief Executive Officer
			
		 		 	GARDANT PHARMACEUTICALS INC.
					
		 		 		 	By:	 	/s/ Lee Cole
		 		 		 		 	Lee Cole
		 		 		 		 	President and Chief Executive Officer

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