Document:

Third Amendment to Office Lease Agreement

 Exhibit 10.1 
 THIRD AMENDMENT 
 THIS THIRD AMENDMENT (the “Amendment”) is made and entered into as of
January 31, 2008, by and between 4350 LA JOLLA VILLAGE LLC, a Delaware limited liability company (“Landlord”), and MEDICINOVA, INC., a Delaware corporation (“Tenant”). 
 RECITALS 
  

	 A.
	 Landlord (as successor in interest to CA-La Jolla II Limited Partnership, a Delaware limited partnership) and Tenant are
parties to that certain lease dated January 28, 2004, which lease has been previously amended by First Amendment dated August 10, 2004, and Second Amendment dated March 21, 2005 (“Second Amendment”) (collectively, the
“Lease”). Pursuant to the Lease, Landlord has leased to Tenant space currently containing approximately 16,609 rentable square feet (the “Premises”) described as Suite No(s). 900, 950, 960, and 970 on the 9th
floor at the building located at 4350 La Jolla Village Drive, San Diego, California, 92122 (the “Building”). 

  

	B.	The Lease by its terms shall expire on February 29, 2008 (“Second Prior Termination Date”), and the parties desire to extend the Term of the Lease with respect to
12,699 rentable square feet, i.e., Suite No.(s) 950, 960, and 970 (collectively known as “Suite 950”) only as shown in Exhibit A attached hereto, all on the following terms and conditions. 

 NOW, THEREFORE, in consideration of the above recitals which by this reference are incorporated herein, the mutual covenants and conditions
contained herein and other valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Landlord and Tenant agree as follows: 
  

	I.	Remeasurement of Suite 950. Landlord and Tenant acknowledge and agree that Landlord has remeasured Suite 950 and that according to the remeasurement, the rentable
square feet of Suite 950 as of the Second Extension Date (as hereinafter defined) is 12,699 rentable square feet. For the period prior to the Second Extension Date, the rentable square feet of Suite 950 shall remain as set forth in the Lease.
However, commencing on the Second Extension Date and continuing throughout the Second Extended Term (as hereinafter defined), the rentable square feet of Suite 950 shall be adjusted to reflect such remeasurement and all references in the Lease to
the “Premises” shall refer to Suite 950. 

  

	II.	Extension for Suite 950. The Term of the Lease with respect to Suite 950 only is hereby extended and shall expire on February 28, 2009 (“Second Extended
Termination Date”), unless sooner terminated in accordance with the terms of the Lease. That portion of the Term commencing the day immediately following the Second Prior Termination Date (“Second Extension Date”) and ending on the
Second Extended Termination Date shall be referred to herein as the “Second Extended Term”. 

  

	III.	Base Rent for Suite 950. As of the Second Extension Date, the schedule of Base Rent payable with respect to the Suite 950 during the Second Extended Term is the
following: 

  

					
	 Months of Term or Period
	 	 Monthly Rate Per
 Square Foot
	 	 Monthly Basic Rent

	 03/01/08 – 02/28/09
	 	$2.75	 	$34,922

 All such Base Rent shall be payable by Tenant in accordance with the terms of the Lease.

  

	IV.	Expenses and Taxes. For the period commencing on the Second Extension Date and ending on the Second Extended Termination Date, Tenant shall be obligated to pay
Tenant’s Pro Rata Share of Expenses and Taxes accruing in connection with Suite 950 in accordance with the terms of the Lease; provided, however, the Base Year for the computation of Tenant’s Pro Rata Share of Expenses and Taxes applicable
to Suite 950 is Landlord’s fiscal year of July 1 through June 30. The Base Year for calculation of Tenant’s Pro Rata Share of Expenses and Taxes in connection with Suite 950 shall be July 1, 2007 through June 30, 2008.
Tenant’s Pro Rata Share for Suite 950 shall be 6.56%. 

  

	V.	Additional Security Deposit. No additional security deposit shall be required in connection with this Amendment. 

  

	VI.	Improvements to Suite 950. 

  

	 	A.	Condition of Premises. Tenant is in possession of Suite 950 and accepts the same “as is” without any agreements, representations, understandings or obligations on
the part of Landlord to perform any alterations, repairs or improvements, except as may be expressly provided otherwise in this Amendment. 

  

	 	B.	Any construction, alterations or improvements to Suite 950 shall be performed by Tenant at its sole cost and expense using contractors selected by Tenant and approved by Landlord
and shall be governed in all respects by the provisions of Section 9 of the Lease. 

  

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	VII.	Parking. Notwithstanding any contrary provision in the “Parking Agreement” attached as Exhibit G to the Lease, effective as of the Second Extension Date,
Landlord shall lease to Tenant, and Tenant shall lease from Landlord, a minimum of ten (10) unreserved parking spaces, but not more than forty-one (41) unreserved parking spaces (the “Allotted Stalls”), at the rate of fifty
dollars $50.00 per stall per month utilized during the Second Extended Term. Prior to the Second Extension Date, Tenant shall deliver notice to Landlord, in writing, of the number of unreserved parking spaces that Tenant desires to utilize.

  

	VIII.	SDN List. Tenant hereby represents and warrants that neither Tenant nor any officer, director, employee, partner, member or other principal of Tenant (collectively,
“Tenant Parties”) is listed as a Specially Designated National and Blocked Person (“SDN”) on the list of such persons and entities issued by the U.S. Treasury Office of Foreign Assets Control (OFAC). In the event Tenant or any
Tenant Party is or becomes listed as an SDN, Tenant shall be deemed in breach of this Lease and Landlord shall have the right to terminate the Lease immediately upon written notice to Tenant. 

  

	IX.	Other Pertinent Provisions. Landlord and Tenant agree that, effective as of the date of this Amendment (unless different effective date(s) is/are specifically
referenced in this Section), the Lease shall be amended in the following additional respects: 

  

	 	A.	Deleted Provisions. As of the Second Extension Date, Exhibit F (Renewal Option) to the Lease, as amended and Section 9.04 (Right of First Offer) of the Second Amendment to the
Lease shall be deleted in their entirety and of no further force or effect. 

  

	 	B.	Landlord’s Notice Address. The notice address for Landlord in Section 1.12 of the Lease entitled “Notice Address(es)”, is hereby deleted in its entirety and the
following substituted in lieu thereof: 

 4350 La Jolla Village LLC 
 The Irvine Company LLC 
 9255 Towne Centre
Drive, Suite 800 
 San Diego, California 92121 
 Attn: Property Manager 
 with a copy of notices to: 
 The Irvine Company LLC 
 P.O. Box 6370

 Newport Beach, CA 92658-6370 
 Attn: Vice President, Operations, Office Properties/San Diego 
  

	X.	GENERAL. 

  

	 	A.	Effect of Amendments. The Lease shall remain in full force and effect except to the extent that it is modified by this Amendment. 

  

	 	B.	Entire Agreement. This Amendment embodies the entire understanding between Landlord and Tenant and can be changed only by a writing signed by Landlord and Tenant. There have
been no additional oral or written representations or agreements. Under no circumstances shall Tenant be entitled to any rent abatement, improvement allowance, leasehold improvements, or any similar economic incentives that may have been provided
Tenant in connection with entering into the Lease, unless specifically set forth in this Amendment. 

  

	 	C.	Counterparts. If this Amendment is executed in counterparts, each is hereby declared to be an original; all, however, shall constitute but one and the same amendment. In any
action or proceeding, any photographic, photostatic, or other copy of this Amendment may be introduced into evidence without foundation. 

  

	 	D.	Defined Terms. All words commencing with initial capital letters in this Amendment and defined in the Lease shall have the same meaning in this Amendment as in the Lease,
unless they are otherwise defined in this Amendment. 

  

	 	E.	Authority. If Tenant is a corporation, limited liability company or partnership, or is comprised of any of them, each individual executing this Amendment for the corporation,
limited liability company or partnership represents that he or she is duly authorized to execute and deliver this Amendment on behalf of such entity and that this Amendment is binding upon such entity in accordance with its terms.

  

	 	F.	Attorneys’ Fees. The provisions of the Lease respecting payment of attorneys’ fees shall also apply to this Amendment. 

  

	 	G.	Execution of Amendment. Submission of this Amendment by Landlord is not an offer to enter into this Amendment but rather is a solicitation for such an offer by Tenant.
Landlord shall not be bound by this Amendment until Landlord has executed and delivered the same to Tenant. 

  

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	 	H.	Nondisclosure of Terms. Except (i) as required by law; (ii) in connection with a dispute or litigation hereunder; (iii) as required by subpoena or
(iv) pursuant to regulations and statutes for publicly traded entities, Tenant agrees that neither Tenant nor its agents or any other parties acting on behalf of Tenant shall disclose any matters set forth in this Amendment or disseminate or
distribute any information concerning the terms, details or conditions hereof to any person, firm or entity. All other disclosures shall require the express written consent of Landlord. Landlord acknowledges that Tenant is required to file this
Amendment with the Securities Exchange Commission. 

 IN WITNESS WHEREOF, Landlord and Tenant have duly executed this
Amendment as of the day and year first above written. 
  

									
	LANDLORD:	 		 	TENANT:
			
	4350 LA JOLLA VILLAGE LLC,	 		 	MEDICINOVA, INC.,
	a Delaware limited liability company	 		 	a Delaware corporation
					
	By:	 	/s/ Steven M. Case	 		 	By:	 	 /s/ Yuichi Iwaki
		 	Steven M. Case	 		 	Printed Name:	 	 Yuichi Iwaki
		 	Senior Vice President, Leasing	 		 	Title:	 	 President and CEO
					
	By:	 	/s/ Michael Bennett	 		 	By:	 	 /s/ Shintaro Asako
		 	Michael T. Bennett	 		 	Printed Name:	 	 Shintaro Asako
		 	Vice President, Operations	 		 	Title:	 	 CFO

  

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 4350 La Jolla Village Drive,
Suite 950 
  
  
 

 
 Exhibit A 
  

 4Amendment No.1 to Registration Rights Agreement

 EXHIBIT 10.1 
 AMENDMENT NO. 1 
 TO 
 REGISTRATION RIGHTS AGREEMENT 
 THIS AMENDMENT NO. 1 (the
“Amendment”) dated as of January 29, 2008 to the Registration Rights Agreement (the “Agreement”) dated as of September 28, 2006 is entered into by and between STONEMOR PARTNERS
L.P., a Delaware limited partnership (the “Company”), acting by its General Partner, STONEMOR GP LLC, a Delaware limited liability company, and SCI NEW MEXICO FUNERAL SERVICES, INC., a New Mexico corporation
(“SCI”). 
 BACKGROUND 
 The Agreement was executed pursuant to that certain Asset Purchase and Sale Agreement dated as of September 28, 2006 (“Asset Purchase Agreement”) to which StoneMor Operating LLC, a
subsidiary of the Company, and affiliates of SCI are party. The parties to the Agreement desire to amend the Agreement as set forth below. 
 NOW, THEREFORE, in consideration of the foregoing and the mutual promises contained herein, and intending to be legally bound hereby, the parties agree as follows: 
 1. Certain Definitions. For purposes of this Amendment: 
 (a) The term “Registrable Securities” means (1) the 275,046 common units (“Common
Units”) of the Company received by SCI pursuant to the Asset Purchase Agreement and (2) any Common Units of the Company issued as a stock dividend or other distribution with respect to, or in exchange for or in replacement of, such
Common Units. 
 (b) The term “trading day” means a day on which The NASDAQ Stock Market is open for
business. 
 2. Amendment. The Agreement is hereby amended by: 
 (i) restating the definition of the term “90-Day Period” to read as follows: 
 “The term “180-Day Period” refers to the one hundred and eighty (180) consecutive trading days after the
effective date of the registration statement with respect to the Registrable Securities.” 
 (ii) replacing the term
“90-Day Period” by the term “180-Day Period” throughout the Agreement. 

 3. Continuing Validity of Agreement. Except as expressly modified or amended hereby, the Agreement
shall continue in full force and effect. 
 4. General. 
 (a) Counterparts. This Amendment may be executed in any number of counterparts, each of which when so executed and delivered shall
be an original hereof, and it shall not be necessary in making proof of this Amendment to produce or account for more than one counterpart hereof. 
 (b) Section Headings. The section and subsection headings in this Amendment are used solely for convenience of reference, do not constitute a part of this Amendment, and shall not affect its interpretation.

 (c) References. All words used in this Amendment shall be construed to be of such number and gender as the context
requires or permits. 
 (d) Controlling Law. THIS AMENDMENT IS MADE UNDER, AND SHALL BE CONSTRUED AND ENFORCED IN
ACCORDANCE WITH, THE LAWS OF THE STATE OF DELAWARE APPLICABLE TO AGREEMENTS MADE AND TO BE PERFORMED SOLELY THEREIN, WITHOUT GIVING EFFECT TO PRINCIPLES OF CONFLICTS OF LAW. IN VIEW OF THE FACT THAT EACH OF THE PARTIES HERETO HAS BEEN REPRESENTED BY
ITS OWN COUNSEL AND THIS AMENDMENT HAS BEEN FULLY NEGOTIATED BY ALL PARTIES, THE LEGAL PRINCIPLE THAT AMBIGUITIES IN A DOCUMENT ARE CONSTRUED AGAINST THE DRAFTSPERSON OF THAT DOCUMENT SHALL NOT APPLY TO THIS AMENDMENT. 
 (e) Entire Agreement; Amendment, Supplement, Waiver or Termination. This Amendment along with the Agreement and the Asset
Purchase Agreement (and all other documents executed in connection therewith) constitute the entire understanding of the parties with respect to the subject manner thereof, and supersede all prior oral and written communications and agreements, and
all contemporaneous oral communications and agreements with respect of the subject matter contained therein. No amendment, supplement, waiver, or termination of this Amendment, in whole or in part, shall be effective unless in writing and signed by
the party against whom enforcement is sought and no written waiver by any party shall be used as a precedent for future waivers. 
 (f) Jurisdiction and Process. In any action between any of the parties, whether arising out of this Amendment or otherwise, (a) each of the parties irrevocably consents to the exclusive jurisdiction and venue of the
federal and state courts located in the State of Delaware; (b) if any such action is commenced in a state court other than the State of Delaware, then, subject to applicable law, no party shall object to the removal of such action to any
federal court located in the State of Delaware; (c) each of the parties irrevocably waives the right to trial by jury; and (d) each of the parties irrevocably consents to service of process by first class 

  

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certified mail, return receipt requested, postage prepaid, to the address at which such party is to receive notice in accordance with the Asset Purchase
Agreement. 
 (g) No Third-Party Beneficiaries. No provision of this Amendment shall be construed to confer any
right to enforce this Amendment, or any remedy for breach of this Amendment, to or upon any individual or entity other than the parties hereto, and there are no third party beneficiaries of this Amendment. 
  

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 In Witness Whereof, the parties hereto have executed this Amendment as of the date first
above written. 
 STONEMOR PARTNERS L.P., a Delaware limited partnership, 
 By: STONEMOR GP LLC, its General Partner 
 /s/ Paul
Waimberg                                       
          
 By: Paul Waimberg 
 Title: Vice President 
  
 SCI NEW MEXICO FUNERAL
SERVICES, INC., a New Mexico corporation 
 /s/ Michael D.
Lehmann                                      

 By: Michael D. Lehmann 
 Title: Vice President

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