Document:

Form of Stock Option Agreement for executive officers and key employees.

 Exhibit 10.21 
  
 REGENERATION TECHNOLOGIES, INC. 
  
 INCENTIVE STOCK OPTION GRANT AGREEMENT 
  
  
 This Grant Agreement (the
“Agreement”) is entered into this      day of                      by and between
REGENERATION TECHNOLOGIES, INC., a Delaware corporation (the “Corporation”), and                      (“Grantee”),
effective as of the Grant Date as defined in Article 1 hereof. 
  
 In consideration of the premises, mutual covenants and agreements herein, the Corporation and the Grantee agree as follows: 
  
 ARTICLE 1 
 GRANT OF OPTION

  
 Section 1.1 Grant of Option. The
Corporation hereby grants to the Grantee, pursuant to the provisions of the Regeneration Technologies, Inc. Omnibus Stock Plan (the “Plan”), an incentive stock option to purchase shares of Common Stock, par value of $0.001 per share, of
the Corporation (“Stock”), subject to the provisions of this Agreement (the “Option”). Unless stated otherwise herein, capitalized terms in this Agreement shall have the same meaning as defined in the Plan. Schedule A, attached
hereto and incorporated herein, sets forth the following terms of the Option: 
  

	 	(i)	the date the Administrator approved the Option (the “Grant Date”); 

  

	 	(ii)	the number of shares of Stock which the Grantee may purchase under the Option; 

  

	 	(iii)	the exercise price per share (the “Exercise Price”); and 

  

	 	(iv)	the date as of which the Option shall expire (the “Expiration Date”), at 5:00 p.m. Eastern Time, unless terminated earlier pursuant to other provisions of this Agreement.

  
 Section 1.2 Limitation on Term of
Option. Notwithstanding the foregoing, in no event shall the Option expire later than 5:00 p.m. Eastern Time on the day prior to the tenth (10th) anniversary of its Grant Date (or on the day prior to the fifth (5th) anniversary of its Grant Date if the Grantee owns stock possessing more than 10% of the total combined voting power of all classes of stock of the Corporation or of any of its subsidiaries on the Grant Date). 
  
 ARTICLE 2 
 VESTING 
  
 Section 2.1 Vesting Schedule. Unless the Option terminates earlier pursuant to other provisions of this Agreement, the Option shall vest and become exercisable as provided in the following schedule: 
  

 Section 2.2 Acceleration of Vesting. Unless the Option has earlier terminated pursuant to
the provision of the Agreement, vesting of the Option shall be accelerated so that all unvested shares of Stock subject to the Option shall become one hundred percent (100%) vested in the Grantee upon a Change of Control. For purposes of this
Agreement, the term “Change of Control” shall mean (i) the sale of all or substantially all of the assets of the Corporation, (ii) the sale of more than fifty percent (50%) of the outstanding common stock of the Corporation in a non-public
sale, (iii) the dissolution or liquidation of the Corporation, or (iv) any merger, share exchange, consolidation or other reorganization or business combination of the Corporation if immediately after such transaction either (A) persons who were
directors of the Corporation immediately prior to such transaction do not constitute at least a majority of the directors of the surviving entity, or (B) persons who hold a majority of the voting capital stock of the surviving entity are not persons
who held a majority of the voting capital stock of the Corporation immediately prior to such transaction. 
  
 ARTICLE 3 
 EXERCISE OF OPTION 
  
 Section 3.1: Exercisability of Option. The Option is
exercisable only if it is vested and has not been terminated. If exercisable, the Option may be exercised in whole or in part, subject to the conditions precedent described in Section 3.3. Only Grantee and, after his death, his executor, personal
representative, or the person to whom the Option shall have been transferred by will or the laws of descent and distribution, may exercise the Option. 
  
 Section 3.2: Manner of Exercise. Grantee or any other person exercising the Option may do so only by delivering written notice thereof to
the Administrator. Such notice shall be in the form as attached hereto, unless the Administrator requires otherwise. Notwithstanding the foregoing, the Option may not be exercised at any one time as to fewer than five (5) Shares or, if less, such
number of Shares as to which the Option is then exercisable. Such notice shall be accompanied by full payment of the Exercise Price. Payment of the Exercise Price shall be made in cash, provided that the Administrator may authorize a payment of the
Exercise Price to be made, in whole or in part, by such other means as the Administrator may prescribe at the time of exercise. The Option may be exercised only in multiples of whole Shares and no fractional Shares shall be issued. If the Common
Stock is registered under Section 12 of the Securities Exchange Act of 1934, as amended, the Exercise Price may be paid, in whole or in part, subject to such limitations as the Administrator may determine, by delivery of a properly executed exercise
notice, together with irrevocable instructions: (i) to a brokerage firm designated by the person exercising the Option and approved by the Administrator to deliver promptly to the Corporation the aggregate amount of sale or loan proceeds to pay the
Exercise Price and any withholding tax obligations that may arise in connection with the exercise, and (ii) to the Corporation to deliver the certificates for such purchased Shares directly to such brokerage firm. 
  
 Section 3.3: Issuance of Shares upon Exercise. Upon exercise of
the Option and payment of the Exercise Price, the Corporation shall issue to Grantee the number of Shares so paid for, in the form of fully paid and nonassessable Common Stock. If the Common Stock is not yet registered under Section 12 of the
Securities Exchange Act of 1934, as amended, the Grantee shall be required to execute and deliver, as a condition precedent to the exercise of the option and the issuance of the Shares to the Grantee, a stockholder agreement and/or stock restriction
agreement which shall contain certain stock restrictions, including but not limited to a waiver of inspection rights, proxy voting, limitations on transfer and other restrictions. The Grantee’s stock certificates shall be held in escrow by the
Corporation during the period that the shares are subject to restriction. The stock certificates for any Shares issued hereunder shall, unless such Shares are registered, bear a legend restricting transferability of such Shares and referencing the
stockholder agreement and stock restriction agreement. 
  

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 ARTICLE 4 
 TERMINATION OF OPTION 
  
 Section 4.1 Termination, In General. The Option granted hereby shall terminate and be of no force or effect after the Expiration Date set forth on Schedule A, unless terminated prior to such time as provided below.
Notwithstanding anything contained herein, vesting of the Option pursuant to Section 2.1 shall cease upon the Grantee’s termination of employment by, or service to, the Corporation, unless otherwise agreed by the Corporation in writing.

  
 Section 4.2 Termination of Employment or Service or for
Reason Other Than Death or Disability. Unless the Option has earlier terminated pursuant to the provisions of the Agreement, the Option shall terminate in its entirety, regardless of whether the Option is vested in whole or in part, thirty
(30) days after the date the Grantee is no longer employed by, or not in the service of, the Corporation and its Affiliates for any reason other than the Grantee’s death or Disability. Notwithstanding the foregoing, the Option shall terminate
in its entirety, regardless of whether the Option is vested in whole or in part, upon termination of the employment or service of the Grantee by the Corporation or an Affiliate for “Cause”. 
  
 If the Grantee is a party to a written employment agreement or service
agreement with the Corporation or an Affiliate then currently in effect which contains a definition of “cause”, “termination for cause” or words of similar import, whether such Grantee is terminated for “Cause” pursuant
to this Section 4.2 shall be determined according to the terms of and in a manner consistent with the provisions of such written agreement. If the Grantee is not party to such a written employment agreement or service agreement with the Corporation
or an Affiliate, then for purposes of this Section 4.2, “Cause” shall mean (a) the conviction of the Grantee of, or the entry of a pleading of guilty or nolo contendere by the Grantee to, any felony or any crime involving moral
turpitude, (b) willful misconduct in connection with the Grantee’s duties, willful failure to follow the directions of the Grantee’s supervisor or supervisors, or willful failure to perform his or her responsibilities in the best interest
of the Corporation, except in cases involving the mental or physical incapacity or disability of the Grantee, or (c) in the sole judgment of the President of the Corporation, the Grantee has acted or is acting in a manner that is not in the best
interest of the Corporation or its employees, including but not limited to, disparaging the Corporation or its products or engaging in harassment or other inappropriate behavior directed towards employees of the Corporation. “Willful
misconduct” and “willful failure to perform” shall not include actions or inactions on the part of the Grantee which were taken or not taken in good faith by the Grantee. The good faith determination by the Administrator of whether
the Grantee’s employment or service was terminated by the Corporation for “Cause” shall be final and binding for all purposes hereunder. 
  
 Section 4.3 Upon Grantee’s Death. Unless the Option has earlier terminated pursuant to the provisions of the Agreement, upon the
Grantee’s death the Grantee’s executor, personal representative, or the person(s) to whom the Option shall have been transferred by will or the laws of descent and distribution, may exercise all or any part of the outstanding Option with
respect to the shares of Stock as to which the Option is vested as of the Grantee’s date of death, provided such exercise occurs within six (6) months after the date of the Grantee’s death, but not later than the Expiration Date of the
Option. Unless sooner terminated, the Option shall terminate upon the expiration of such six (6) month period. 
  
 Section 4.4 Termination of Employment or Service by Reason of Disability. Unless the Option has earlier terminated pursuant to the
provisions of the Agreement, in the event that the Grantee ceases, by reason of Disability, to be an employee of or in the service of the Corporation or an Affiliate, the outstanding Option may be exercised in whole or in part with respect to the
shares of Stock as to which the Option is vested as of the date of the Grantee’s termination of employment or service due to Disability at any time within six (6) months after the date of such termination, but not later than the Expiration Date
of the Option. Unless sooner terminated, the Option shall terminate upon the expiration of such six (6) month period. 
  
 For purposes of this Agreement, Disability shall mean the inability to engage in any substantial gainful activity by reason of any medically determinable
physical or mental impairment which can be expected to result in death or which has lasted or can be expected to last for a continuous period of not less than twelve (12) months. The Administrator may require such proof of Disability as the
Administrator in its sole discretion deems appropriate and the Administrator’s determination as to whether the Grantee is Disabled shall be final and binding on all parties concerned. 
  

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 Section 4.5 Leave of Absence. For purposes of this Agreement, the Grantee’s employment
or service with the Corporation or an Affiliate shall not be deemed to terminate if the Grantee takes any military leave, sick leave, or other bona fide leave of absence approved by the Administrator of ninety (90) days or less. In the event of a
leave in excess of ninety (90) days, the Grantee’s employment or service shall be deemed to terminate on the ninety-first (91st) day of the leave unless the Grantee’s right to re-employment with the Corporation or Affiliate remains
guaranteed by statute or contract. Notwithstanding the foregoing, unless otherwise determined by the Administrator (or required by law), a leave of absence shall not be treated as employment or service for purposes of vesting in additional shares of
Stock during such leave pursuant to Section 2.1 of this Agreement. 
  
 ARTICLE 5 
 ADJUSTMENTS; BUSINESS COMBINATIONS 
  
 Section 5.1 Adjustments for Events Affecting Common Stock. In the event of changes in the Common Stock of the
Corporation by reason of any stock dividend, split-up, recapitalization, merger, consolidation, business combination or exchange of shares and the like, the Administrator shall, in its discretion, make appropriate adjustments to the number, kind and
price of shares covered by this Option, and shall, in its discretion and without the consent of the Grantee, make any other adjustments in this Option, including but not limited to reducing the number of shares subject to the Option or providing or
mandating alternative settlement methods such as settlement of the Option in cash or in shares of Common Stock or other securities of the Corporation or of any other entity, or in any other matters which relate to the Option as the Administrator
shall, in its sole discretion, determine to be necessary or appropriate. 
  
 Section 5.2 Adjustments for Unusual Events. The Administrator is authorized to make, in its discretion and without the consent of the Grantee, adjustments in the terms and conditions of, and the criteria
included in, the Option in recognition of unusual or nonrecurring events affecting the Corporation, or the financial statements of the Corporation or any Subsidiary, or of changes in applicable laws, regulations, or accounting principles, whenever
the Administrator determines that such adjustments are appropriate in order to prevent dilution or enlargement of the benefits or potential benefits intended to be made available under the Option or the Plan. 
  
 Section 5.3 Binding Nature of Adjustments. Adjustments under
this Article 5 will be made by the Administrator, whose determination as to what adjustments, if any, will be made and the extent thereof will be final, binding and conclusive. No fractional shares will be issued pursuant to this Option on account
of any such adjustments. 
  
 ARTICLE 6 
 MISCELLANEOUS 
  
 Section 6.1 Non-Guarantee of Employment. Nothing in the Plan or this Agreement shall alter the employment status of the Grantee, nor be
construed as a contract of employment between the Corporation (or an Affiliate) and the Grantee, or as a contractual right of the Grantee to continue in the employ or service of the Corporation (or an Affiliate), or as a limitation of the right of
the Corporation (or an Affiliate) to discharge the Grantee at any time with or without cause or notice. 
  
 Section 6.2 No Rights of Stockholder. The Grantee shall not have any of the rights of a stockholder with respect to the shares of Stock that
may be issued upon the exercise of the Option until such shares of Stock have been issued upon the due exercise of the Option, subject to and in accordance with the provisions of Section 3.3. No adjustment shall be made for dividends or
distributions or other rights for which the record date is prior to the date such certificate or certificates are issued. 
  

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 Section 6.3 Nature of Option. The Option is intended to be a stock option that qualifies as
an incentive stock option (“Incentive Stock Option”) within the meaning of Section 422 of the Internal Revenue Code of 1986, as amended, to the fullest extent permitted within the limit set forth under Section 422(d) of the Code, and this
Agreement shall be so construed. The aggregate fair market value (determined as of the Grant Date) of the shares of Stock with respect to which all Incentive Stock Options first become exercisable by the Grantee in any calendar year under the Plan
or any other plan of the Corporation (and its parent and subsidiary corporations, as may exist from time to time) may not exceed $100,000 or such other amount as may be permitted from time to time under Section 422 of the Code. To the extent that
such aggregated fair market value shall exceed $100,000 or other applicable amount in any calendar year, such stock options shall be treated as nonqualified stock options with respect to the amount of the aggregate fair market value thereof that
exceeds the Section 422(d) limit. For this purpose, the Incentive Stock Options will be taken into account in the order in which they were granted. In such case, the Corporation may designate the shares of Stock that are to be treated as stock
acquired pursuant to a nonqualified stock option by issuing separate certificates for such shares and identifying the certificates as such in the stock transfer records of the Corporation. 
  
 Section 6.4 Notice of Disqualifying Disposition. If the Grantee
makes a disposition (as that term is defined in Section 424(c) of the Code) of any shares of Stock acquired pursuant to the exercise of this Option within two (2) years of the Grant Date or within one (1) year after the shares of Stock are
transferred to the Grantee, the Grantee shall notify the Administrator of such disposition in writing within thirty (30) days of the disposition. 
  
 Section 6.5 The Corporation’s Rights. The existence of this Option shall not affect in any way the right or power of the Corporation or
its stockholders to make or authorize any or all adjustments, recapitalizations, reorganizations or other changes in the Corporation’s capital structure or its business, or any merger or consolidation of the Corporation, or any issue of bonds,
debentures, preferred or other stocks with preference ahead of or convertible into, or otherwise affecting the Stock or the rights thereof, or the dissolution or liquidation of the Corporation, or any sale or transfer of all or any part of the
Corporation’s assets or business, or any other corporate act or proceeding, whether of a similar character or otherwise. 
  
 Section 6.6 Withholding of Taxes. The Corporation or any Affiliate shall have the right to deduct from any compensation or any other payment
of any kind (including withholding the issuance of shares of Stock) due the Grantee the amount of any foreign, federal, state or local taxes required by law to be withheld as the result of the exercise of the Option or the lapsing of any restriction
with respect to any shares of Stock acquired on exercise of the Option; provided, however, that the value of the shares of Stock withheld may not exceed the statutory minimum withholding amount required by law. In lieu of such deduction, the
Administrator may require the Grantee to make a cash payment to the Corporation or an Affiliate equal to the amount required to be withheld. If the Grantee does not make such payment when requested, the Corporation may refuse to issue any Stock
certificate under the Plan until arrangements satisfactory to the Administrator for such payment have been made. 
  
 Section 6.7 Grantee. Whenever the word “Grantee” is used in any provision of this Agreement under circumstances where the
provision should logically be construed to apply to the estate, personal representative or beneficiary to whom this Option may be transferred by will or by the laws of descent and distribution, the word “Grantee” shall be deemed to include
such person. 
  
 Section 6.8 Nontransferability of
Option. The Option shall be nontransferable otherwise than by will or the laws of descent and distribution and during the lifetime of the Grantee, the Option may be exercised only by the Grantee or, during the period the Grantee is under a
legal disability, by the Grantee’s guardian or legal representative. Except as provided in the preceding sentence, the Option may not be assigned, transferred, pledged, hypothecated or disposed of in any way (whether by operation of law or
otherwise) and shall not be subject to execution, attachment or similar process. 
  
 Section 6.9 Notices. All notices and other communications made or given pursuant to the Agreement shall be in writing and shall be sufficiently made or given if hand delivered or mailed by certified
mail, addressed to the Grantee at the address contained in the records of the Corporation, or addressed to the Administrator, care of the Corporation for the attention of its Secretary at its principal office or, if the receiving party consents in
advance, transmitted and received via telecopy or via such other electronic transmission mechanism as may be available to the parties. 
  

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 Section 6.10 Entire Agreement; Modification. This Agreement contains the entire agreement
between the parties with respect to the subject matter contained herein and may not be modified, except as provided in the Plan or in a written document signed by each of the parties hereto. Any oral or written agreements, representations,
warranties, written inducements, or other communications made prior to the execution of the Agreement shall be void and ineffective for all purposes. 
  
 Section 6.11 Conformity with Plan. This Agreement is intended to conform in all respects with, and is subject to all applicable provisions
of, the Plan, which is incorporated herein by reference. Inconsistencies between this Agreement and the Plan shall be resolved in accordance with the terms of the Plan. In the event of any ambiguity in the Agreement or any matters as to which the
Agreement is silent, the Plan shall govern. A copy of the Plan is available upon request to the Administrator. 
  
 Section 6.12 Governing Law. This Agreement shall be governed by and construed in accordance with the laws of the State of Delaware, other
than the conflict of laws principles thereof. 
  
 Section
6.13 Headings. The headings in the Agreement are for reference purposes only and shall not affect the meaning or interpretation of the Agreement. 
  
 [signatures on next page] 
  

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 IN WITNESS WHEREOF, the Corporation has caused this Agreement, which shall be effective as of the Grant
Date, to be executed by its duly authorized officer, and the Grantee has hereunto set his hand and seal. 
  

					
	ATTEST:	 	 REGENERATION TECHNOLOGIES, INC.

			
	  

	 	By:	 	  

	 	 	 	 	 
	 	 	Date:	 	  

  

					
		
	WITNESS:	 	GRANTEE:
		
	  

	 	  

	 	 	Name:
	 	 	Date:	 	  

  

							
	 	 	 	 	SSN: (Required)	 	  

  

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 SCHEDULE A 
  
 OF REGENERATION TECHNOLOGIES, INC. 
  
 INCENTIVE STOCK OPTION GRANT AGREEMENT 
  

			
	Name of Grantee:	    	 
		
	 Date Option Was Approved
 By
Plan Administrator:
	    	 
		
	Number of Shares:	    	                     shares of Common Stock of
		
	 	    	Regeneration Technologies, Inc.
		
	Exercise Price Per Share:	    	                     per share
		
	Expiration Date:	    	Ten (10) Years from Grant Date

 EXERCISE FORM 
  
 Stock Option Plan Administrator 
 c/o Office of
the Corporate Secretary 
 Regeneration Technologies, Inc. 
 11621
Research Circle 
 Alachua, Florida 32615 
  
 Gentlemen: 
  
 I hereby exercise the Option granted to me on                     ,
             by Regeneration Technologies, Inc. (the “Corporation”), subject to all the terms and provisions thereof and of the Regeneration Technologies, Inc. Omnibus
Stock Plan (the “Plan”), and notify you of my desire to purchase                      shares of Common Stock of the Corporation at a
price of $[            ] per share pursuant to the exercise of said Option. 
  

			
	Total Amount Enclosed: $            	 	 
		
	Date:                     	 	.                                      
                                      
	 	 	Grantee
		
	 	 	Received by Regeneration Technologies, Inc. on:
	 	 	                                      
                      ,
                
		
	 	 	By:Certified Resolutions of the Board of Directors

 Exhibit 10.18 
  
 CERTIFIED RESOLUTIONS OF THE BOARD OF DIRECTORS 
 OF 
 WESBANCO, INC. 
  
 I hereby certify that I am the Secretary of Wesbanco, Inc., a corporation,
with its principal office and place of business located in Wheeling, West Virginia, and that I have been duly appointed and am presently serving in that capacity in accordance with the Bylaws of said corporation. 
  
 I further certify that at a meeting of the Executive Committee of the Board
of Directors of the corporation duly called in accordance with the Bylaws of said corporation and convened on the 19th day of January, 2005, the following resolutions were adopted by unanimous vote of all of the members of the Executive Committee
present and participating: 
  
 RESOLVED,
that the Committee hereby approves certain changes to the compensation to be paid to the members of the Board of Directors and the Executive Committee effective January 1, 2005, by increasing the meeting fee for each meeting of the Executive
Committee of the Board of Directors to $1,250.00 per meeting attended and increasing the meeting fee for members of the Board of Directors to $1,000.00 per meeting attended effective with the February meeting with the quarterly retainer to be
retained at its current amount of $1,500.00 per calendar quarter. 
  
 The foregoing resolution is presently in full force and effect and has not been revoked or rescinded as of the date hereof. 
  
 IN WITNESS WHEREOF, I have hereunto set my hand and affixed the seal of this corporation this 14th day of March, 2005. 
  

	
	
	/S/    LARRY
JOHNSON        
	Larry Johnson, Secretary

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