Document:

EX-10.12

 Exhibit 10.12 

Execution Version 

PROMISSORY NOTE PURCHASE AGREEMENT 

This Promissory Note Purchase Agreement (including all exhibits hereto, this “Agreement”) is made as of February 22,
2016 (the “Effective Date”), between AquaBounty Technologies, Inc., a Delaware corporation (“AquaBounty”), and Intrexon Corporation, a Virginia corporation (“Intrexon”). 

WHEREAS, upon the terms and conditions set forth in this Agreement, AquaBounty proposes to issue to Intrexon one or more promissory notes with
commitments in an aggregate principal amount not to exceed $10,000,000, each in substantially the same form as Exhibit A hereto (the “Notes”), upon the terms and conditions set forth herein and therein; and

 WHEREAS, Intrexon has agreed to make such loans to AquaBounty subject to the terms and conditions contained herein and in the Notes. 

NOW, THEREFORE, in consideration of the foregoing premises and the mutual covenants and conditions set forth herein, the parties hereto agree
as follows: 
 ARTICLE I 

DEFINITIONS 
 Section 1.1
Definitions. 
 In addition to the terms defined elsewhere herein, when used herein, the following terms shall have the meanings
indicated hereunder: 
 “Act” means the Securities Act of 1933, as amended, and the rules and regulations of the SEC
thereunder. 
 “Affiliate” means, with respect to any Person, any other Person who controls, is controlled by, or is under
common control with such Person. 
 “AIM Market” means AIM, a market operated by the London Stock Exchange. 

“Board” means the Board of Directors of AquaBounty. 

“Business Day” means any day other than a Saturday, Sunday, or other day on which commercial banks in the State of Delaware
are authorized or required by law or executive order to close. 
 “Capital Stock” means all of AquaBounty’s issued and
outstanding equity securities. 
 “Commitment” means the amount of capital that Intrexon agrees to fund to AquaBounty in
exchange for each Note under the terms set forth therein. 
 “Contractual Obligation” means, as to any Person, any
provision of any security issued by such Person or of any agreement, undertaking, contract, indenture, mortgage, deed of trust, or other instrument to which such Person is a party or by which it or any of its property is bound. 

“GAAP” means U.S. generally accepted accounting principles as in effect from time to time. 

 “Governmental Authority” means the AIM Market; any federal, state, or local
governmental or quasi-governmental instrumentality, agency, board, commission, or department; or any regulatory agency, bureau, commission, or authority. 

“Lien” means any mortgage, deed of trust, pledge, hypothecation, assignment, encumbrance, lien (statutory or other) or
preference, priority, right, or other security interest or preferential arrangement of any kind or nature whatsoever (excluding preferred stock and equity-related preferences), including, without limitation, those created by, arising under, or
evidencing substantially the same economic effect as any of the foregoing. 
 “Material Adverse Effect” means, subject to
any applicable cure or grace periods, a material adverse effect upon (a) the financial condition, operations, business, or properties of AquaBounty; (b) the ability of AquaBounty to perform its material obligations under any of the
Transaction Documents; or (c) the legality, validity, or enforceability of any of the Transaction Documents. 

“Order” means any judgment, injunction, writ, award, decree, or order of any nature. 

“Person” means any individual, group of individuals, firm, corporation, partnership, trust, incorporated or unincorporated
association, joint venture, joint stock company, limited liability company, Governmental Authority, or other entity of any kind and shall include any successor (by merger or otherwise) of such entity. 

“Requirement of Law” means, as to any Person, any law, statute, treaty, rule, regulation, or determination of an arbitrator
or a court or other Governmental Authority that is applicable to or binding upon such Person or any of its property, or to which such Person or any of its property is subject, or that pertains to the transactions contemplated or referred to herein.

 “SEC” means the Securities and Exchange Commission or any similar agency then having jurisdiction to enforce the Act.

 “Securities Filings” means the filing of any filing required by the SEC under the Act, any filing required pursuant to
the rules of the AIM Market, or any filing with the Delaware Corporations Commission under the Delaware General Corporation Law by AquaBounty, in each case in respect of its issuance of the Notes. 

“Transaction Documents” means, collectively, this Agreement and the Notes. 

Section 1.2 Accounting Terms; Financial Statements. 

All accounting terms used herein not expressly defined in this Agreement shall have the respective meanings given to them in accordance with
sound accounting practice. The term “sound accounting practice” shall mean such accounting practice as, in the opinion of the independent certified public accountants regularly retained by AquaBounty, conforms at the time to GAAP
applied on a consistent basis except for changes with which such accountants concur. 

  
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 ARTICLE II 

PURCHASE AND SALE OF THE NOTES 
 Section
2.1 Purchase and Sale of the Notes. 
 (a) Subject to the terms and conditions set forth herein, AquaBounty may issue and sell to
Intrexon, and Intrexon hereby agrees to purchase from AquaBounty, one or more Notes, each with a Commitment in an amount designated by AquaBounty (with respect to any Note, the “Purchase Price”) subject to the following limitations:
(i) each Note shall be for a principal amount evenly divisible by $2,500,000 and (ii) all Notes issued hereunder shall have aggregate Commitments of no more than $10,000,000. Intrexon agrees to be bound by the terms and conditions of
each Note issued to Intrexon hereunder. 
 (b) From and after the Effective Date, for a period of one year, AquaBounty may notify Intrexon
of its desire to sell to Intrexon one or more Notes and shall provide Intrexon with a request substantially in the form of Exhibit B attached hereto (each a “Compliance Certificate”), completed to the
satisfaction of Intrexon and delivered as provided in Section 7.2. Each Compliance Certificate shall be provided at least three Business Days prior to the prospective sale of the applicable Note. 

Section 2.2 Closings. 
 The closing
of the sale and purchase of each Note (a “Closing”) shall take place on the date set forth in the Compliance Certificate (a “Closing Date”). On each Closing Date, AquaBounty shall deliver the applicable Note,
and, upon satisfaction of the conditions set forth herein and in that Note, Intrexon will fund the principal amount thereof. 
 ARTICLE
III 
 REPRESENTATIONS AND WARRANTIES OF AQUABOUNTY 

AquaBounty represents and warrants to Intrexon that the statements contained in this Article III are true, complete, and correct as of
each Closing Date. For purposes of the representations and warranties set forth in this Article III, AquaBounty will be deemed to have “knowledge” of a particular fact or other matter if an officer or director of AquaBounty is
actually aware of such fact or other matter. 
 Section 3.1 Organization and Standing. 

AquaBounty is a corporation duly organized, validly existing, and in good standing under the laws of the State of Delaware and has all
requisite corporate power and authority to carry on its business as now conducted. AquaBounty is duly qualified to transact business and is in good standing in each jurisdiction in which the failure to so qualify would have a Material Adverse
Effect. 
 Section 3.2 Authorization; Enforceability. 

(a) AquaBounty has all requisite corporate power and authority to execute, deliver, and perform, as applicable, the Transaction Documents. 

(b) AquaBounty and its officers, directors, and shareholders have taken all corporate action necessary for (i) the authorization,
execution, delivery, and performance of all obligations of 

  
 3 

 
AquaBounty under each of the Transaction Documents and (ii) the issuance and sale by AquaBounty of the Notes hereunder. Each of the Transaction Documents constitutes a valid and legally
binding obligation of AquaBounty, enforceable in accordance with its terms, except (A) as limited by applicable bankruptcy, insolvency, reorganization, moratorium, and other laws of general application affecting enforcement of creditors’
rights generally or by equitable principles; (B) as limited by laws relating to the availability of specific performance, injunctive relief, or other equitable remedies; and (C) to the extent that the enforceability of the indemnification
provisions may be limited by applicable laws (such limitations, collectively, the “Equitable Exceptions”). 
 Section 3.3 Validity of
Notes and Issuance. 
 The Notes (a) are duly authorized; (b) when issued and sold to Intrexon will be validly issued; and
(c) will be free and clear of any and all liens, charges, restrictions, claims, and encumbrances except as set forth in this Agreement or as otherwise created by Intrexon. 

Section 3.4 Compliance with Law and Instruments. 

To AquaBounty’s knowledge, the execution, delivery, and performance of and compliance with this Agreement and the issuance and sale of the
Notes will not, with or without the passage of time or giving of notice, violate (a) any applicable statute, rule, regulation, order, or restriction of any domestic or foreign government or any instrumentality or agency thereof in respect of
the conduct of its business or the ownership of its properties; (b) any term of AquaBounty’s organizational documents; (c) any provision of any mortgage, indenture, contract, agreement, instrument, or contract to which it is party or
by which it is bound; or (d) any Order by which it is bound. 
 Section 3.5 Consents. 

No consent, approval, order, or authorization of, or registration, qualification, designation, declaration, or filing with, any federal, state,
or local Governmental Authority or any other Person is required in connection with the consummation of the transactions contemplated by this Agreement, except for compliance with notice filings and other requirements under federal and applicable
state securities laws. 
 Section 3.6 Offering Exemption. 

Based in part on the representations of Intrexon set forth in Article IV, the offer, sale, and issuance of the Notes in conformity with
the terms and conditions set forth in this Agreement and in the Notes are exempt from the registration requirements of the Act and are exempt from the qualification or registration requirements of applicable state securities laws. Neither
AquaBounty nor any agent on its behalf has solicited or will solicit any offers to sell or has offered to sell or will offer to sell all or any part of the Notes to any Person or Persons so as to bring the sale of such Notes by AquaBounty within the
registration provisions of the Act or any state securities laws. 
 Section 3.7 Brokers and Finders. 

AquaBounty agrees to indemnify and hold harmless Intrexon from any liability for any commission or compensation in the nature of a
finder’s or broker’s fee arising out of this Agreement or the transactions contemplated hereby (and the costs and expenses of defending against such liability or asserted liability) for which AquaBounty or any of its officers, employees,
or representatives is responsible. 

  
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 ARTICLE IV 

REPRESENTATIONS AND WARRANTIES OF INTREXON 

As a material inducement to AquaBounty to enter into and perform its obligations under this Agreement, Intrexon represents and warrants to
AquaBounty that the statements contained in this Article IV are true, complete, and correct as of the Effective Date. 
 Section 4.1
Authorization; Enforceability. 
 Intrexon has all requisite power and authority to execute, deliver, and perform this
Agreement. Intrexon and, as applicable, its directors, officers, members, partners, and shareholders have taken all action necessary for the authorization, execution, delivery, and performance of all obligations of Intrexon under this
Agreement. This Agreement constitutes the valid and legally binding obligation of Intrexon, enforceable in accordance with its terms, except as limited by the Equitable Exceptions. 

Section 4.2 Investor Representations. 

(a) The Notes will be acquired by Intrexon for its own account for investment purposes and not with a view to, or for sale in connection with,
any distribution. Intrexon does not presently have any contract, undertaking, or agreement with any Person to sell, transfer, or grant participation rights to such Person or to any other Person with respect to any of the Notes. 

(b) Intrexon is an “accredited investor” within the meaning of Rule 501(a) promulgated under the Act. 

(c) Intrexon understands that the Notes are characterized as “restricted securities” under the federal securities laws inasmuch as
they are being acquired from AquaBounty in a transaction not involving a public offering and that under such laws and applicable regulations such securities may be resold without registration under the Act only in certain limited
circumstances. Intrexon acknowledges and agrees that the Notes must be held indefinitely unless they are subsequently registered under the Act or an exemption from such registration is available. Intrexon understands that no public market
now exists for the Notes and that a public market may never exist for the Notes. 
 (d) Intrexon acknowledges and agrees that it can bear
the economic risk of its investment in the Notes and has such knowledge and experience in financial or business matters that it is capable of evaluating the merits and risks of the investment in the Notes. 

(e) Intrexon was not contacted by AquaBounty or its representatives for the purpose of investing in any securities of AquaBounty offered
hereby through any advertisement, article, notice, or any other communication published in any newspaper, magazine, or similar media or broadcast over television or radio, or any seminar or meeting whose attendees were invited by any general
advertising. The Notes purchased under this Agreement were not offered or sold to Intrexon by any form of general solicitation or general advertising. 

  
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 (f) Intrexon has not agreed to incur, directly or indirectly, any liability for brokerage or
finders’ fees, agents’ commissions, or other similar charges in connection with this Agreement or any of the transactions contemplated hereby. 

Section 4.3 Legends. 
 Intrexon
acknowledges and agrees that the instruments evidencing the Notes may bear such restrictive legends as required by law. 
 ARTICLE V

 CONDITIONS TO THE OBLIGATION OF INTREXON TO CLOSE 

The obligation of Intrexon to purchase the Notes and to perform any obligations hereunder with respect to each Closing shall be subject to the
satisfaction as determined by, or waiver by, Intrexon of the following conditions on or before that Closing. 
 Section 5.1 Representations and
Warranties. 
 The representations of AquaBounty contained in Article III shall be true and correct in all material respects,
and the warranties in that Article shall remain in effect, at and as of the applicable Closing Date (except with respect to such representations that address matters only as of a particular date, which are true and correct as of such particular
date). 
 Section 5.2 Compliance with this Agreement. 

AquaBounty shall have performed and complied in all material respects with all of its agreements and conditions set forth herein that are
required to be performed or complied with by AquaBounty on or before the applicable Closing Date. 
 Section 5.3 Secretary’s
Certificate. 
 The Secretary of AquaBounty shall have signed and delivered to Intrexon on behalf of AquaBounty a certificate, in
form and substance satisfactory to Intrexon and dated as of the applicable Closing Date, certifying (a) that the Board resolutions attached thereto approving each of the Transaction Documents to which AquaBounty is a party and the transactions
contemplated thereby are all true, complete, and correct and remain unamended and in full force and effect and (b) as to the incumbency and specimen signature of each officer of AquaBounty executing each Transaction Document or other document
delivered in connection with that Closing on behalf of AquaBounty. 
 Section 5.4 Note. 

AquaBounty shall have executed and delivered to Intrexon the applicable Note. 

Section 5.5 Consents and Approvals. 

Except for the Securities Filings, all consents, exemptions, authorizations, and other actions by, or notices to, or filings with, any
Governmental Authority or any other Person required in respect of any Requirement of Law and with respect to each Contractual Obligation of AquaBounty that is necessary in 

  
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connection with the execution, delivery, or performance by, or enforcement against, AquaBounty of each of the Transaction Documents shall have been obtained and be in full force and effect, and
Intrexon shall have been furnished with appropriate evidence thereof. 
 Section 5.6 No Material Judgment or Order. 

There shall be no Order of a court of competent jurisdiction, Lien under any Contractual Obligation, ruling of any Governmental Authority, or
condition imposed under any Requirement of Law that, in the reasonable judgment of Intrexon, would prohibit the purchase of the Notes or subject Intrexon to any penalty or other onerous condition under or pursuant to any Requirement of Law if the
Notes were to be purchased hereunder. 
 Section 5.7 No Litigation. 

No action, suit, proceeding, claim, or dispute shall have been brought or otherwise arisen against AquaBounty (whether at law, in equity, in
arbitration, or before any Governmental Authority) that would, if adversely determined, have a Material Adverse Effect. 
 ARTICLE VI

 CONDITIONS TO THE OBLIGATIONS OF AQUABOUNTY TO CLOSE 

The obligations of AquaBounty to issue and sell the Notes and to perform its other obligations hereunder, shall be subject to the
satisfaction, as determined by, or written waiver by, AquaBounty of the following conditions on or before each Closing Date. 
 Section 6.1
Representations and Warranties. 
 The representations of Intrexon contained in Article IV shall be true and correct in all
material respects, and the warranties in that Article shall remain in effect, at and as of the applicable Closing Date (except with respect to such representations that address matters only as of a particular date, which are true and correct as of
such particular date). 
 Section 6.2 Compliance with this Agreement. 

Intrexon shall have performed and complied in all material respects with all of the agreements and conditions set forth herein that are
required to be performed or complied with by Intrexon on or before the applicable Closing Date. 
 Section 6.3 No Material Judgment or Order.

 On the applicable Closing Date, there shall be no Order of a court of competent jurisdiction, Lien under any Contractual Obligation,
ruling of any Governmental Authority, or condition imposed under any Requirement of Law that, in the reasonable judgment of AquaBounty, would prohibit the sale of the applicable Note or subject AquaBounty to any penalty or other onerous condition
under or pursuant to any Requirement of Law if that Note were to be purchased hereunder. 

  
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 Section 6.4 Consents and Approvals. 

Except for the Securities Filings, all consents, exemptions, authorizations, or other actions by, or notices to, or filings with, Governmental
Authorities and other Persons required in respect of any Requirement of Law and with respect to each Contractual Obligation of Intrexon that is necessary in connection with the execution, delivery, or performance by, or enforcement against, Intrexon
of each of the Transaction Documents shall have been obtained and be in full force and effect, and AquaBounty shall have been furnished with appropriate evidence thereof. 

Section 6.5 Purchase Price. 

AquaBounty shall have received the Purchase Price from Intrexon for the Note to be acquired during the applicable Closing. 

ARTICLE VII 

MISCELLANEOUS 
 Section 7.1 Survival
of Representations and Warranties. 
 All of the representations and warranties made herein shall survive the execution and delivery
of this Agreement until the first anniversary of the Effective Date. 
 Section 7.2 Notices. 

All notices, demands, and other communications required or permitted hereunder shall be in writing and shall be given by registered or
certified first-class mail (return receipt requested), facsimile, electronic mail, courier service, or personal delivery to the address or number for the intended recipient set forth below or such other address or number as may be provided by notice
from the intended recipient from time to time. 
  

	 	(a)	if to AquaBounty: 

 AquaBounty Technologies, Inc. 

Two Clock Tower Place, Suite 395 

Maynard, MA 01754 
 Attention:
David Frank 
 Facsimile: 978-897-3217 

E-mail: dfrank@aquabounty.com 
  

	 	(b)	if to Intrexon: 

 Intrexon Corporation 

1750 Kraft Drive, Suite 1400 

Blacksburg, VA 24060 
 Attention:
Rick L. Sterling, Chief Financial Officer 
 Facsimile: 540-961-0925 

E-mail: rsterling@intrexon.com 

  
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 with a copy (which shall not constitute notice) to: 

Intrexon Corporation 
 20358
Seneca Meadows Parkway 
 Germantown, MD 20876 

Attention: Legal Department 

Facsimile: 301-556-9901 
 E-mail:
dlehr@intrexon.com 
 All such communications shall be deemed to have been duly given when delivered by hand, if personally delivered; when
delivered by courier, if delivered by commercial courier service; five Business Days after being deposited in the mail, postage prepaid, if mailed; and upon receipt, if sent via facsimile or electronic mail. 

Section 7.3 Successors and Assigns; Third-Party Beneficiaries. 

This Agreement shall inure to the benefit of and be binding upon the successors and permitted assigns of the parties hereto. Subject to
applicable securities laws and the terms of the applicable Transaction Documents, Intrexon may assign any of its rights under any of the Transaction Documents to any of its Affiliates and, with the prior written consent of AquaBounty, to any Person
that is not an Affiliate of Intrexon. AquaBounty may not assign any of its rights under this Agreement without the prior written consent of Intrexon. No Person other than the parties hereto and their successors are intended to be
beneficiaries of the provisions of this Agreement. 
 Section 7.4 Amendment and Waiver. 

(a) No failure or delay on the part of AquaBounty or Intrexon in exercising any right, power, or remedy hereunder shall operate as a waiver
thereof, nor shall any single or partial exercise of any such right, power, or remedy preclude any other or further exercise thereof or the exercise of any other right, power, or remedy. The remedies provided for herein are cumulative and are
not exclusive of any remedies that may be available to AquaBounty or Intrexon at law, in equity, or otherwise. 
 (b) Any amendment,
supplement, modification, or waiver of or to any provision of this Agreement must be in a written agreement signed by both parties hereto and shall be effective only in the specific instance and for the specific purpose for which made or
given. Except where notice is specifically required by this Agreement, no notice to or demand on AquaBounty in any case shall entitle AquaBounty to any other further notice or demand in similar or other circumstances. 

Section 7.5 Counterparts; Facsimile or Electronic Transmission. 

This Agreement may be executed in any number of counterparts, each being deemed to be an original and all of which taken together being deemed
to constitute a single agreement. Such counterparts may be delivered by facsimile or as a .pdf file by electronic mail. 
 Section 7.6
Headings. 
 The headings in this Agreement are for convenience only and shall not limit or otherwise affect the meaning hereof.

  
 9 

 Section 7.7 Governing Law. 

This Agreement shall be governed by and construed in accordance with the laws of the State of Delaware, without regard to the conflict of laws
principles thereof. 
 Section 7.8 Severability. 

If any provision of this Agreement, or the application thereof in any circumstance, is held invalid, illegal, or unenforceable in any respect
for any reason, the validity, legality, and enforceability of such provision in every other respect and of the remaining provisions hereof shall not be in any way impaired, unless the provision held invalid, illegal, or unenforceable shall
substantially impair the benefits of the remaining provisions hereof. 
 Section 7.9 Rules of Construction. 

Unless the context otherwise requires, references to articles, sections, or subsections refer to articles, sections, or subsections of this
Agreement. 
 Section 7.10 Entire Agreement. 

The Transaction Documents are intended by the parties hereto as a complete and final expression of their agreement in respect of the subject
matter of those documents and supersede all prior agreements and understandings between the parties with respect to such subject matter. There are no restrictions, promises, representations, warranties, or undertakings other than those set
forth or referred to in the Transaction Documents. 
 Section 7.11 Fees. 

Each party hereto shall be responsible for all costs, fees, and expenses it incurs (including, without limitation, those of counsel) in
connection with the transactions contemplated hereby, including, without limitation, any amendment or modification of the Transaction Documents. 

Section 7.12 Publicity; Confidentiality. 

Neither of the parties hereto shall make any disclosure concerning this Agreement, the transactions contemplated hereby, or, with respect to
Intrexon, regarding the business, technology, or financial affairs of AquaBounty, without prior approval by the other party; provided, however, that nothing in this Agreement shall restrict AquaBounty or Intrexon from disclosing information
(a) that is already publicly available; (b) that was known to Intrexon on a non-confidential basis prior to its disclosure by AquaBounty; (c) that may be required or appropriate in response to any summons or subpoena or in connection
with any litigation, provided that the parties will use reasonable efforts to notify the other party in advance of such disclosure so as to permit such party to seek a protective order or otherwise contest such disclosure, and such other party will
use reasonable efforts to cooperate, at the expense of the party trying to prevent such disclosure, with such party in pursuing any such protective order; (d) to the extent that Intrexon or AquaBounty reasonably believes it appropriate in order
to comply with any Requirement of Law; (e) to Intrexon’s or AquaBounty’s officers, directors, shareholders, agents, employees, members, partners, controlling persons, auditors, or counsel; (f) to Persons from whom releases,
consents, or approvals are required, or to whom notice is required to be 

  
 10 

 
provided, pursuant to the transactions contemplated by the Transaction Documents; or (g) to the prospective transferee in connection with any contemplated transfer of any Note. If any
announcement is required by law or the rules of any securities exchange or market on which shares of Capital Stock of AquaBounty are traded to be made by any party hereto, prior to making such announcement such party will deliver a draft of such
announcement to the other party and shall give the other party reasonable opportunity to comment thereon. 
 Section 7.13 Further Assurances.

 Each of the parties shall execute such documents and perform such further acts (including, without limitation, obtaining any consents,
exemptions, authorizations, or other actions of, or giving any notices to, or making any filings with, any Governmental Authority or any other Person) as may be reasonably required or desirable to carry out or to perform the provisions of this
Agreement. 
 Section 7.14 Waiver of Jury Trial and Setoff; Consent to Jurisdiction; Etc. 

(a) In any litigation with respect to, in connection with, or arising out of this Agreement or any instrument or document delivered pursuant to
this Agreement, or the validity, protection, interpretation, collection, or enforcement hereof or thereof, or any other claim or dispute howsoever arising, between AquaBounty and Intrexon, the parties hereby waive, to the fullest extent they may
legally do so, (i) the right to interpose any setoff, recoupment, counterclaim, or cross-claim in connection with any such litigation, irrespective of the nature of such setoff, recoupment, counterclaim, or cross-claim, unless such setoff,
recoupment, counterclaim, or cross-claim could not, by reason of any applicable federal or state procedural laws, be interposed, pleaded, or alleged in any other action and (ii) TRIAL BY JURY IN CONNECTION WITH ANY SUCH
LITIGATION. AQUABOUNTY AGREES THAT THIS SECTION 7.14(a) IS A SPECIFIC AND MATERIAL ASPECT OF THIS AGREEMENT AND ACKNOWLEDGES THAT INTREXON WOULD NOT EXTEND ANY CREDIT TO AQUABOUNTY IF THIS SECTION 7.14(a) WERE NOT PART OF THIS
AGREEMENT. 
 (b) The parties hereby irrevocably consent to the exclusive jurisdiction of the courts located within the State of Delaware in
connection with any action or proceeding arising out of or relating to this Agreement or any document or instrument delivered in connection with the transactions contemplated hereby. In such litigation, AquaBounty waives, to the fullest extent
it may effectively do so, any personal service of any summons, complaint, or other process and agrees that the service thereof may be made by certified or registered mail directed to AquaBounty at its address set forth in this
Agreement. AquaBounty hereby waives, to the fullest extent it may effectively do so, the defenses of forum non conveniens and improper venue. 

[remainder of page intentionally left blank] 

  
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 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be executed and delivered by
their respective officers hereunto duly authorized on the date first set forth above. 
  

			
	AQUABOUNTY TECHNOLOGIES, INC.
		
	By:	 	 /s/ David A. Frank

		 	David A. Frank
		 	Chief Financial Officer
	
	INTREXON CORPORATION
		
	By:	 	   /s/ Donald P. Lehr

		 	Name: Donald P. Lehr
		 	Title: Chief Legal Officer

 [Signature Page to Promissory Note Purchase Agreement] 

 EXHIBIT A 

FORM OF PROMISSORY NOTE 

 THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED
(THE “ACT”), OR ANY APPLICABLE STATE SECURITIES LAWS. IT MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED, OR HYPOTHECATED IN THE ABSENCE OF A REGISTRATION STATEMENT IN EFFECT WITH RESPECT TO THE SECURITY UNDER SUCH ACT OR AN
OPINION OF COUNSEL SATISFACTORY TO AQUABOUNTY THAT SUCH REGISTRATION IS NOT REQUIRED. 
 CONVERTIBLE PROMISSORY NOTE 

 

			
	 $2,500,000
	 	February     , 2016

 FOR VALUE RECEIVED, the undersigned, AquaBounty Technologies, Inc., a Delaware corporation, with an address of
Two Clock Tower Place, Suite 395, Maynard, MA 01754 (together with its successors and permitted assigns, “AquaBounty”), hereby promises to pay to the order of Intrexon Corporation, a Virginia corporation (together with its successors and
assigns, “Intrexon”), at 1750 Kraft Drive, Suite 1400, Blacksburg, VA 24060, or at such other place as may be designated from time to time in writing by Intrexon, in lawful money of the United States of America, without setoff, the
principal sum of $2,500,000, or such lesser amount as may be advanced and remain outstanding from time to time, together with simple interest thereon at the rate provided below, all in accordance with the following terms and provisions: 

1.    Definitions. Capitalized terms used in this Convertible Promissory Note (as in effect from time to time, the
“Note”) but not defined herein shall have the meanings ascribed thereto in that certain Promissory Note Purchase Agreement by and among AquaBounty and Intrexon, dated as of February 16, 2016 (as in effect from time to time, the
“Purchase Agreement”). The following terms, unless the context otherwise requires, have the following meanings: 

a.    “Common Stock” means AquaBounty’s common stock, par value $0.001 per share. 

b.    “Copyrights” means any foreign or United States copyright registrations, applications for
registration thereof, and any non-registered copyrights. 
 c.    “Event of Default” has the meaning
set forth in Section 16 of this Note. 
 d.    “Indebtedness” means, as to any Person,
(i) all obligations of such Person (A) for borrowed money (including, without limitation, reimbursement and all other obligations with respect to surety bonds, letters of credit, and bankers’ acceptances, whether or not matured);
(B) evidenced by notes, bonds, debentures, or similar instruments; (C) to pay the deferred purchase price of property or services, except trade accounts payable and accrued commercial or trade liabilities arising in the ordinary course of
business; or (D) under leases that have been or should be, in accordance with GAAP, recorded as capital leases; (ii) all interest rate and currency swaps, caps, collars, and similar agreements or hedging devices under which payments are
obligated to be made by such Person, whether periodically or upon the happening of a contingency; and (iii) all indebtedness (A) created or arising under any conditional sale or other title retention agreement with respect to property
acquired by such Person (even though the 

 
rights and remedies of the seller or lender under such agreement in the event of default are limited to repossession or sale of such property); or (B) secured by any Lien (other than Liens
in favor of lessors under leases not included in clause (i)(D) above) on any property or asset owned or held by that Person regardless of whether the indebtedness secured thereby shall have been assumed by that Person or its non-recourse to the
credit of that Person. 
 e.    “Intellectual Property” means Copyrights, Patents, Trade Secrets,
Trademarks, Internet Assets, software (excluding “off the shelf” software) and other proprietary rights. 

f.    “Internet Assets” mean any internet domain names and other computer user identifiers and any rights
in and to sites on the worldwide web, including rights in and to any text, graphics, audio and video files, and html or other code incorporated in such sites. 

g.    “Loan” has the meaning set forth in Section 3 of this Note. 

h.    “Maturity Date” shall mean March 1, 2017, or such later date as may be agreed to by Intrexon
in writing. 
 i.    “Patents” means any foreign or United States patents and patent applications,
(including any divisionals, continuations, continuations-in-part, substitutions, or reissues thereof), whether or not patents are issued on such applications or such applications are modified, withdrawn, or resubmitted. 

j.    “Offering” means the first issuance and sale of shares of Common Stock that occurs prior to the
repayment in full of the outstanding principal balance of this Note and all accrued interest thereon, excluding the grant, issuance, or sale or any security by AquaBounty to any employee or director in such capacity. 

k.    “Trade Secrets” means any scientific or technical information, design, process, procedure, formula,
or improvement that derives independent economic value from not being generally known, and not being readily ascertainable through proper means, to AquaBounty’s competitors or other persons who can obtain economic value from its use. To
the fullest extent consistent with the foregoing, and otherwise lawful, Trade Secrets shall include, without limitation, information and documentation pertaining to the design, specifications, testing, validation, implementation, and customizing
techniques and procedures concerning AquaBounty’s products and services. 
 l.    “Trademarks”
means any foreign or United States trademarks, service marks, trade dress, trade names, brand names, designs and logos, corporate names, and product or service identifiers, whether registered or unregistered, and all registrations and applications
for registration thereof. 
 2.    Purchase Agreement. This Note is one of the Notes executed and delivered by AquaBounty
pursuant to the terms and conditions of the Purchase Agreement and is subject to the terms and conditions thereof. 

3.    Loans. Upon the terms and subject to the conditions of this Note and the Purchase Agreement, Intrexon agrees to make a
loan (the “Loan”) to AquaBounty on the Closing Date, in 

 
an amount up to $2,500,000. Intrexon may endorse and attach a schedule to reflect the borrowing of the Loan evidenced by this Note and all payments and permitted prepayments thereon;
provided that any failure to endorse such information shall not affect the obligation of AquaBounty to pay amounts evidenced hereby. Any and all borrowing under this Note shall be in the manner set forth in Section 2.3 of the
Purchase Agreement. 
 4.    Use of Proceeds. The Loan made by Intrexon to AquaBounty hereunder may only be used for working
capital and other general corporate purposes of AquaBounty. 
 5.    Interest Rate. The unpaid principal balance of this
Note outstanding from time to time shall bear interest at a simple rate of interest equal to 10% per annum. After the occurrence and during the continuance of an Event of Default, interest shall accrue on all amounts due hereunder at a simple
rate of interest equal to 15% per annum. Interest shall be calculated on the basis of actual number of days elapsed over a year of 360 days. 

6.    Interest Payments. Without the prior written consent of Intrexon, AquaBounty shall not be permitted to make a payment of
interest under this Note prior to the Maturity Date or such earlier date that this Note is repaid pursuant to Section 8 of this Note. 

7.    Principal Payments. If not sooner paid, the entire unpaid principal balance of this Note and all unpaid accrued interest
thereon shall be due and payable on the Maturity Date. 
 8.    Prepayment. This Note may be prepaid in whole or in part at
any time at the election of AquaBounty. 
 9.    Application of Payments. Payments made by AquaBounty pursuant to the terms
hereof shall be applied as follows: first, to any unpaid accrued collection costs and expenses; second, to any unpaid accrued interest; and third, to the principal balance of this Note. 

10.    Conversion. The aggregate outstanding balance of principal and accrued interest on this and all other Notes shall be
converted into shares of Common Stock at a price per share equal to the closing market price for Common Stock on the AIM market on the Effective Date (as defined in the Purchase Agreement) upon (a) the closing of any Offering or
(b) written notice from Intrexon to AquaBounty of Intrexon’s election to so convert. If such conversion would result in the issuance of a fractional share of Common Stock, AquaBounty shall, in lieu of issuance of any fractional share,
pay Intrexon a sum in cash equal to the product of the then-current fair market value of one share of Common Stock, multiplied by such fraction. Upon such conversion, Intrexon shall surrender this Note to AquaBounty, this Note shall be deemed
cancelled, and the Purchase Agreement shall be deemed terminated. 
 11.    Assignment. Subject to the restrictions on
transfer described in Section 13 of this Note, the rights and obligations of AquaBounty and Intrexon shall be binding upon and inure to the benefit of their respective permitted successors, assigns, heirs, administrators, and transferees. 

12.    Amendment. Any provision of this Note may be amended or modified with the prior written consent of both Intrexon and
AquaBounty. 

 13.    Transfer. Subject to applicable securities laws, Intrexon may assign this
Note or any of its rights hereunder to any of its Affiliates and, with the prior written consent of AquaBounty, to any other Person. With respect to any such transfer of this Note, Intrexon will give written notice to AquaBounty prior thereto,
describing briefly the manner thereof, together with a written opinion of Intrexon’s counsel, in a form reasonably satisfactory to AquaBounty, to the effect that such offer, sale, or other distribution may be effected without registration or
qualification under any federal or state law then in effect. Promptly upon receiving such written notice and opinion of counsel, AquaBounty, as promptly as practicable but in no event later than five Business Days after such receipt, shall
notify Intrexon that Intrexon may sell or otherwise dispose of this Note in accordance with the terms of the notice delivered to AquaBounty, subject to any additional applicable restrictions, including without limitation restrictions set forth in
any Transaction Document. If AquaBounty determines that the opinion of counsel for Intrexon is not reasonably satisfactory to AquaBounty, AquaBounty shall so notify Intrexon promptly after such determination has been made. Each Note thus
transferred shall bear a legend as to the applicable restrictions on transferability in order to ensure compliance with the Act, unless in the opinion of counsel for AquaBounty such legend is not required, in order to ensure compliance with the
registration or qualification requirement of any federal or state law then in effect. AquaBounty may issue stop transfer instructions to its transfer agent in connection with such restrictions. 

14.    Shareholder Status. Intrexon or its Affiliates currently own certain Capital Stock of AquaBounty. Nothing
contained in this Note shall be construed as conferring upon Intrexon any additional rights to vote or to receive dividends or to consent or to receive notice as a shareholder in respect of any meeting of shareholders for the election of directors
of AquaBounty or of any other matter, or any rights whatsoever as a shareholder of AquaBounty. 
 15.    Negative
Covenants. So long as there remains any outstanding and unpaid principal or interest under this Note, AquaBounty hereby agrees to abide by the restrictions and negative covenants set forth in this Section 15, unless AquaBounty first
obtains the written consent of Intrexon to permit AquaBounty to take the action that would otherwise result in a breach of this Section 15. 

a.    Financing. AquaBounty shall not raise capital through the issuance of equity or debt, or any instruments
convertible into or exchangeable for equity or debt, unless, in connection with and contemporaneous with the closing of such financing, AquaBounty shall repay this Note in full. Notwithstanding the foregoing, AquaBounty shall be permitted to
incur indebtedness without repayment of this Note pursuant to proposed financing arrangements (the “Proposed Loans”) between Aqua Bounty Canada Inc., a Newfoundland and Labrador corporation (“ABC”), and
(A) Finance PEI, a crown corporation of the Prince Edward Island Department of Economic Development and Tourism, for an initial principal amount of up to US$600,000, and (B) the Atlantic Canada Opportunities Agency, a Canadian federal
agency (“ACOA”), for an initial principal amount of up to US$400,000. 

b.    Liens. AquaBounty shall not (i) create, incur, assume, or suffer to exist any Lien upon any of the
property or assets of AquaBounty or (ii) suffer to exist for a period of more than 30 days after the same shall have been incurred any Indebtedness or claim against it in excess of $100,000 that, if unpaid, would by law or upon bankruptcy or
insolvency, or otherwise, be entitled to any priority whatsoever over Intrexon other than trade credit incurred in the ordinary 

 
course of business; provided, however, that AquaBounty may incur and suffer to exist Liens (A) in favor of Intrexon under any Note in compliance with the terms hereof;
(B) imposed by law, which were incurred in the ordinary course of business, do not secure Indebtedness for borrowed money arising in the ordinary course of business, and do not in the aggregate materially detract from the value of its property
or assets or materially impair the use thereof in the operation of business; (C) for taxes, fees, assessments, or other government charges or levies, either not delinquent or being contested in good faith and for which AquaBounty maintains
adequate reserves on its books; (D) arising in connection with leases or subleases of real property granted in the ordinary course of business, and licenses or sublicenses of property granted in the ordinary course of AquaBounty’s
business; (E) arising from judgments, decrees, or attachments in circumstances not constituting an Event of Default under any of the Transaction Documents; (F) in favor of financial institutions arising in connection with AquaBounty’s
deposit and/or securities accounts held at such institutions; (G) in connection with purchase money Indebtedness for equipment and capitalized leases of equipment, provided that such security interests only attach to the equipment the purchase
of which was financed by such purchase money Indebtedness or which is the subject of such capitalized leases and the proceeds thereof; or (H) arising in connection with either of the Proposed Loans or a financing arrangement between ABC and
ACOA under Contract Number 193648, entered into as of December 16, 2009. 
 c.    Dissolution; Sale of
Assets. AquaBounty shall not dissolve, reorganize, liquidate, or sell any of its assets to any Person or enter into any merger or consolidation with any Person except (i) dispositions of assets or property of AquaBounty of $100,000 or
less, individually or collectively, (ii) sales or leases of AquaBounty’s products in the ordinary course of business, (iii) grants of non-exclusive licenses of Intellectual Property in the ordinary course of business, and
(iv) dispositions in the ordinary course of business. 
 d.    Obligations Under this Note. AquaBounty
shall not, by amendment of its organizational documents or through any reorganization, transfer of assets, consolidation, merger, dissolution, issue or sale of securities, or any other voluntary action, avoid or seek to avoid the observance or
performance of any of the terms of this Note, but shall at all times in good faith assist in the carrying out of all such terms and in the taking of all such actions as may be necessary or appropriate in order to protect the rights of Intrexon
hereunder. 
 16.    Default and Remedies. If any of the events specified in this Section 16 shall occur (each, an
“Event of Default”), Intrexon may, so long as such condition exists (after giving effect to any applicable cure period set forth below), declare the entire outstanding principal balance and unpaid accrued interest hereon immediately
due and payable, by notice in writing to AquaBounty. 
 a.    Default in the payment of the principal or unpaid accrued
interest on this Note when due and payable if such default is not cured by AquaBounty within fifteen Business Days after AquaBounty receives written notice of such default. 

b.    A material default in the observance or performance of any other covenant or agreement contained in this Note or the
Purchase Agreement, which default continues for a period of fifteen Business Days after AquaBounty receives written notice specifying the default. 

 c.    The failure to pay at final stated maturity (giving effect to any
applicable grace periods and any extensions thereof) (i) any trade credit of AquaBounty incurred in the ordinary course of business that has an outstanding principal balance in excess of $100,000 or (ii) any other Indebtedness of
AquaBounty or, in each case, the acceleration of any such Indebtedness (which acceleration is not rescinded, annulled, or otherwise cured within fifteen Business Days after receipt by AquaBounty of notice of any such acceleration). 

d.    The institution by AquaBounty of proceedings to be adjudicated as bankrupt or insolvent; the consent by it to
institution of bankruptcy or insolvency proceedings against it; the filing by it of a petition, answer, or consent seeking reorganization or release under Title 11 of the United States Code, or any other applicable federal or state law; the consent
by it to the filing of any such petition or the appointment of a receiver, liquidator, assignee, trustee, or other similar official of AquaBounty or any substantial part of its property; or the making by it of an assignment for the benefit of
creditors, in each case that is not dismissed within 60 days of the commencement thereof. 
 e.    If, within 60 days
after the commencement of an action against AquaBounty (and service of process in connection therewith on AquaBounty) seeking any bankruptcy, insolvency, reorganization, liquidation, dissolution, or similar relief under any present or future
statute, law, or regulation, (i) such action shall not have been resolved in favor of AquaBounty or all orders or proceedings thereunder affecting the operations or the business of AquaBounty stayed; (ii) the stay of any such order or
proceeding shall thereafter be set aside; or (iii) within 60 days after the appointment without the consent or acquiescence of AquaBounty of any trustee, receiver, or liquidator of AquaBounty of all or any substantial part of its properties,
such appointment shall not have been vacated. 
 f.    The decision by the Board to cease or substantially cease its
operations or wind up the affairs of AquaBounty. 
 g.    The occurrence of an event of default or material breach, as
applicable, under any of the Transaction Documents if such default or breach is not cured by AquaBounty within fifteen Business Days after AquaBounty receives written notice of such default. 

17.    Allocation of Costs. If this Note is not paid in accordance with its terms, AquaBounty shall pay to Intrexon, in
addition to principal and accrued interest thereon, all costs of collection of the principal and accrued interest, including, but not limited to, reasonable attorneys’ fees, court costs, and other costs for the enforcement of payment of this
Note. 
 18.    Waiver. No waiver of any obligation of AquaBounty under this Note shall be effective unless it is in a
writing signed by Intrexon. A waiver by Intrexon of any right or remedy under this Note on any occasion shall not be a bar to exercise of the same right or remedy on any subsequent occasion or of any other right or remedy at any
time. AquaBounty hereby expressly waives presentment; demand; protest; notice of demand, dishonor, and nonpayment; and all other notices or demands of any kind in connection with the delivery, acceptance, performance, default, or enforcement
hereof, except as expressly provided for herein or in any other Transaction Document, and hereby consents to any delays, extensions of time, renewals, or waivers that may be granted or consented to by Intrexon with respect to the time of payment or
any other provision hereof. 

 19.    Notices. Each notice or other communication provided for or permitted
hereunder shall be made in writing and shall be delivered by registered or certified first-class mail (return receipt requested), facsimile, electronic mail, courier service, or personal delivery to the address or number for each intended recipient
listed in the Purchase Agreement. Such communications shall be deemed to have been duly given when delivered by hand, if personally delivered; when delivered by courier, if delivered by commercial courier service; five Business Days after being
deposited in the mail, if mailed; and upon receipt, if sent via facsimile or electronic mail. 
 20.    Governing Law. This
Note is delivered in and shall be enforceable and construed in accordance with the laws of the State of Delaware (other than its conflict of laws principles). 

21.    Severability. If any provision of this Note shall for any reason be held to be invalid, illegal, or unenforceable, in
whole or in part or in any respect, or operate or would operate to invalidate this Note, then such provision shall be deemed null and void, and the remaining provisions of this Note shall remain operative and in full force and effect and in no way
shall be affected, prejudiced, or disturbed thereby. 
 22.    No Personal Liability. No officer, director, or shareholder
of AquaBounty or any Person executing this Note on behalf of AquaBounty shall be liable personally or be subject to any personal liability or accountability with respect to the obligations of this Note or the Purchase Agreement by reason of the
issuance hereof. 

 IN WITNESS WHEREOF, AquaBounty has executed and delivered this Note as of the date first set
forth above. 
  

			
	 AQUABOUNTY TECHNOLOGIES, INC.

		
	By:	 	 
		 	David A. Frank
		 	Chief Financial Officer

 [Signature Page to Convertible Promissory Note] 

 EXHIBIT B 

FORM OF COMPLIANCE CERTIFICATE 

I,                 , hereby certify, as of this
     day of                     , 20    , that I am the duly elected, qualified, and serving Chief Financial
Officer of AquaBounty Technologies, Inc., a Delaware corporation (“AquaBounty”). This Compliance Certificate (this “Certificate”) is being delivered pursuant to Section 2.1 of that certain Promissory Note
Purchase Agreement, dated as of February 16, 2016, by and between AquaBounty and Intrexon Corporation (the “Agreement”). Capitalized terms appearing in this Certificate, but not otherwise defined, shall have the meanings
given to them in the Agreement. 
 Pursuant to the Agreement, AquaBounty hereby gives notice of its desire to sell to Intrexon a Note in
accordance with the terms of the Agreement and as set forth below: 
 The initial principal amount of such Note shall be
$        , and the Closing Date shall be                     , 20    . 

I hereby certify, solely in my capacity as Chief Financial Officer of AquaBounty, that as of the date hereof, there exists no Event of Default
(as defined in the Note being sold in reliance on this Certificate). 
 IN WITNESS WHEREOF, the undersigned has duly executed this
Compliance Certificate as of the date first set forth above. 
  

			
	AQUABOUNTY TECHNOLOGIES, INC.
		
	By:	 	      

		 	[Name]
		 	Chief Financial OfficerEX-10.13

 Exhibit 10.13 

THE COMMONWEALTH OF MASSACHUSETTS 

William Francis Galvin 
 Secretary
of the Commonwealth 
  

			
	
APOSTILLE
 (Convention de La
Haye du 5 octobre 1961)

	 	 
	 1.   Country:

  This public document
	  	 United States of America

 

	 	 
	2.   has been signed by:	  	Caillin D. Wall
	 	 
	3.   acting in the capacity of:	  	Notary Public
	 	 
	 4.   bears the seal/stamp of:

  whose commission expires on:
	  	 Caillin D. Wall

November 28, 2019

	 
	Certified              

	 	 
	5.   at: Boston, Massachusetts	  	 6. the: 26 June, 2013

	7.   by: the Secretary of the Commonwealth	  	 
	8.   No.: 1677755	  	 
	9.   Seal/stamp:	  	 Great Seal of the Commonwealth

	 	 
	10. Signature	  	 
	/s/ William Francis Galvin	  	 
	 	 
	 William Francis Galvin

Secretary of the Commonwealth
	  	 

 UNITED STATES OF AMERICA 

COMMONWEALTH OF MASSACHUSETTS 
 Middlesex,
ss 
 On this 20th day of June, 2013, before me, the undersigned notary public, personally appeared
David A. Frank and proved to me through satisfactory evidence of identification, which was a driver’s license, to be the person whose name is signed on the preceding or attached document, and who swore or affirmed to me that the contents of the
document are truthful and accurate to the best of his knowledge and belief. 
  

	
	 /s/ Caillin Wall

	Caillin Wall
	Notary Public
	My Commission Expires: November 28, 2019

 LEASE AND MANAGEMENT AGREEMENT 

This Lease and Management Agreement (“Agreement”) is made and entered into as of 1 October 2013 (the “Effective Date”), by and
between LUIS LAMASTUS, male, Panamanian, of legal age, married, with identity card No. #-###-### (“LANDLORD”), on one hand, and on the other hand, DAVID FRANK, male, American (USA), of legal age, with passport No. #########,
acting in name and on behalf of AQUA BOUNTY PANAMA, S. de R.L., a company duly organized and existing under the laws of the Republic of Panama, registered under Microjacket 1017, Document 1363400 of the Mercantile Section of the Public
Registry of the Republic of Panama, (“ABP”) duly authorized to that end, as registered before the Public Registry, (each individually a “Party” and both collectively the “Parties”). 

RECITALS 
 WHEREAS, the LANDLORD owns
possessory rights over a property of approximately 21 hectares, located in Los Naranjos, District of Boquete, Province of Chiriqui, Republic of Panama (the “Property”). 

WHEREAS, the Property is adjacent to a river flow that originates from the Rio Caldera (“River Flow”), with an average water flow of 95,000
gallons per minute during the rainy season, that is key for the purpose of this Agreement. 
 WHEREAS, the LANDLORD is the only owner of the Property and
has had the total control and use of the Property, for sixteen (16) years, including the River Flow but for the 2.03 hectares previously given in usufruct to ABP. Furthermore, the Property is under a titling process before the National Property
Administration Authority (ANATI) to obtain an official property title. 
 WHEREAS, the Property was subject to a usufruct agreement entered into and between
the LANDLORD and ABP (the “Previous Usufruct Agreement”). 
 WHEREAS, the LANDLORD wishes to lease to ABP, and ABP wishes to lease from the
LANDLORD, a portion of 2.03 hectares of the Property adjacent to the River Flow, that is described and depicted in EXHIBIT A attached hereto that constitutes part of this Agreement (the “Parcel”). 

Whereas, the Parcel is free and clear from any encumbrances, liens or restrictions. Furthermore, the Property is in good standing from any fees or taxes
applicable from any public or private institutions. 
 Whereas, there are no claims or disputes over the possessory rights and/or title rights of the
LANDLORD on the Parcel or of any other nature. 
 Whereas, ABP is developing an aquaculture project in the Parcel identified as “Aqua Bounty Panama
Project” consisting of the production of genetically modified salmon (the “ABP Project”) that requires (i) the importation of AquAdvantage Salmon (“AAS”) eggs from the facilities of Aqua Bounty Technologies
(“ABT”) and (ii) grow-out of the AAS. 

 WHEREAS, ABP will obtain from ABT the AAS eggs from ABT and will ship them to Panama for production. 

Whereas, ABP made capital investments and improvements to the Parcel during the term of the Previous Usufruct Agreement, consisting of the following
(“FACILITIES AND EQUIPMENT”): 
  

	1.	The buildings contained on the Parcel, including, but not limited to, the quarantine building containing the fry tanks, egg incubation system, feed warehouse and office. 

 

	2.	The structures, including, but not limited to, the small LHO (“Low Head Oxygenator”), large LHO, concrete water intake and distribution structure, containment sump, and sedimentation pond outlet structures.

  

	3.	The fry tanks and external grow-out tanks. 

  

	4.	The containment components, including the filters and screens, filter boxes, containment sump screens, sedimentations ponds including their outlet screens, and perimeter fencing. 

 

	5.	Water distribution components, including river and spring water intakes, pipes, drainage canal, and sedimentation ponds. 

  

	6.	Electrical generation system, including the solar panels, hydroelectric turbine, and associated electrical transmission and storage components. 

WHEREAS, in furtherance of this ABP Project, ABP wishes to obtain from the LANDLORD, and the LANDLORD wishes to provide to ABP the management services
specified in this Agreement in connection with the ABP Project. 
 NOW, THEREFORE, in consideration of the premises described above, and of the mutual
benefits and obligations set forth in this Agreement, the Parties hereto agree as follows: 
 The Recitals set forth above are material to this Agreement
and are hereby expressly incorporated herein. 
 ARTICLE 1. LEASE 

The LANDLORD hereby leases to ABP the following: 
  

	 	1.	The Parcel described in EXHIBIT A and all its inherent benefits. 

  

	 	2.	The River Flow and spring water adjacent to the Parcel. 

 ARTICLE 2. MANAGEMENT SERVICES 

The LANDLORD may use the FACILITIES AND EQUIPMENT and is obliged to provide the following management services: 

2.1 Carry on the daily management of the ABP Project; 

  
 -2- 

 2.2 Obtain all the permits and authorizations required for the Property and the ABP Project to comply with the
regulations of Panama, including, but not limited to import permits and any permit and/or authorization before the National Environmental Authority (ANAM), Ministry of Agricultural Development (MIDA), Aquatic Resources Authority of Panama (ARAP),
and the National Bio-safety Commission (Comisión Nacional de Bioseguridad- CNB); 
 2.3 Purchase local and imported feeds; 

2.4 Take care of the security within the ABP Project; 
 2.5
Harvest the product on the dates established to that end by ABP; 
 2.6 Maintain the necessary stock of food for the salmons, and parts for repairing the
facilities within the ABP Project; 
 2.7 Transfer the AAS from the incubation system to the fry tanks, and from the fry tanks to the growout tanks as
indicated and/or established by ABP; 
 2.8 Maintain the facilities within the ABP Project in good conditions to guarantee the health, safety, and survival
of the AAS and the ABP Project; 
 2.9 Assume the minor legal expenses related to the administration of the ABP Project, and not covered in Article 9.6;

 2.10 Pay all the operating expenses of the ABP Project, including but not limited to, all salaries for full time and part time employees, feed, oxygen,
gas, supplies, equipment, maintenance, utilities, and costs related to regulatory compliance; and 
 2.11 Maintain a minimum of 100 AAS alive in the
ABP Project. 
 ARTICLE 3. PARCEL AND WATER USE 

3.1 ABP shall only use the Parcel for activities related to the ABP Project. 

3.2 ABP shall use the Parcel with the diligence of a good pater familias and shall not allow the Parcel to be used for any unlawful purpose. 

3.3 ABP shall make any additional improvements that it deems convenient and/or necessary to develop the ABP Project without the approval of the LANDLORD. 

3.4 Unless there is a cause that originates from Acts of God, the ABP Project will have access to the River Flow and to spring water at the same volumes that
are currently in use in the ABP Project and in no event shall these volumes be lower than 2170 gallons per minute of river water for the growout tanks and 130 gallons per minute of spring water for the fry tanks. 

3.5 The water distribution system of the ABP Project will be managed by the LANDLORD. The LANDLORD will not diminish, increase or in any way endanger the
water levels in the ABP Project’s drainage canal and sedimentation ponds without the written consent of ABP. 

  
 -3- 

 3.6 In the event that the LANDLORD develops production facilities that require water use in his portion of the
Property, ABP shall share with the LANDLORD, without any cost to the LANDLORD, a portion of the water flow contained in the water distribution system only if the water requirements for the ABP Project are met. 

ARTICLE 4. TERM 
 The term of this Agreement shall
be two (2) years as of the Effective date (“Term”). 
 ARTICLE 5. LANDLORD OBLIGATIONS AND PROHIBITIONS 

5.1 The LANDLORD shall guarantee ABP the peaceful and uninterrupted use of the Parcel. 

5.2 The LANDLORD shall make any repair that is needed to preserve the Parcel for the use of ABP for the purposes herein established. 

5.3 The LANDLORD shall not impose any liens or restrictions for the use of the Property during the Term of this Agreement. Shall the LANDLORD sell or transfer
his possessory rights over the Property, the contract covering the sale or transfer of the possessory rights over the Property to the new owner shall include the duty of the new owner to respect this Agreement. In any case, ABP has the right to
exercise any actions that it deems convenient or necessary to guarantee that the Parcel, the equipment and the Improvements are free and clear from any liens or restriction of use. 

5.4 The LANDLORD agrees not to modify or interfere with any of the existing AAS production facilities, containment, and/or water distribution systems of the
ABP Project without prior written authorization of ABP and/or ABT. The LANDLORD will not jeopardize, negatively impact or increase effluent flow into the project drainage canal and sedimentation ponds without the written authorization of ABP. The
LANDLORD has knowledge that any unauthorized change to the facilities of the ABP Project that were previously inspected by the FDA could jeopardize ABT’s Food and Drug Administration (FDA) application. 

5.5 The LANDLORD also agrees to staff the ABP Project with at least the following persons, all which shall be employees of the LANDLORD or of a company of its
control: Luis Lamastus as Manager, plus a minimum of four (4) production staff comprised of: (i) one (1) experienced supervisor; and (ii) three (3) workers (“Production Staff”). None of the Production Staff shall
be considered an employee of ABP. 
 5.6 Whenever there are AAS in the ABP Project, the LANDLORD will make every effort to assure that there is a minimum of
one (1) LANDLORD employee present at the ABP Project twenty four (24) hours per day, seven (7) days per week. ABP and/or ABT will continue to visit and monitor the ABP Project, and if there is indication that the health, well-being or
survival of the salmon is being endangered by the Production Staff, ABT will notify the LANDLORD in writing, and the LANDLORD will immediately replace the Production Staff with the necessary biologists and/or technicians trained in fish biology.

 ARTICLE 6. LANDLORD RIGHTS 
 6.1 The LANDLORD
is permitted to build on the Property outside the borders of the Parcel, in accordance with the Property borders established in EXHIBIT A, as long as the construction and new infrastructure does not impede the development of the ABP Project, damages
or 

  
 -4- 

 
interferes with (i) the existing ABP Project infrastructure; (ii) the equipment; (iii) containment elements and/or (iv) the River Flow and spring water used in the ABP Project
and the effluent. The LANDLORD must advise ABP in writing before making any constructions or additions to the infrastructure of the ABP Project for ABP and shall await for ABP to authorize them. 

6.2 The LANDLORD has the right to receive the monthly fee described in Article 9.1. 

6.3 The LANDLORD has the right to receive technical assistance from ABP when needed. 

ARTICLE 7. ABP OBLIGATIONS 
 ABP shall provide the
LANDLORD with the following: 
 7.1 The Canadian Food Inspection Agency (CFIA) export permits for all the AAS egg shipments to Panama from Canada
(Shipment); 
 7.2 All the permits that are required by the laws of Panama to introduce the Shipment from Canada to Panama, including Aquatic Animal Health
Certificates and Export Permits from Canada for the National Directorship of Animal Health of Panama (Autoridad Nacional de Salud Animal-DINASA and/or the Animal Quarantine Directorship (Dirección de Cuarentena Animal – DECA)
permits or eligibility renewals; 
 7.3 The Shipment; 
 7.4
The technical assistance when required or needed; and 
 7.5 The payment of the monthly fee described in Article 9.1 of this Agreement. 

ARTICLE 8. ABP RIGHTS 
 8.1 ABP has the right to:

  

	 	1.	Enter the ABP Project at any time without prior notice to the LANDLORD. 

  

	 	2.	Impose its technical and management parameters on the management of the ABP Project to guarantee the survival, performance, and production of the AAS, in accordance with Article 8.2. 

8.2 All of the technical parameters for the management of the ABP project (including, but not limited to, the stocking densities, optimal ASS biomasses, feed
types and rates, size grading and population reduction, mean harvest weight, and harvest scheduling) will be mutually agreed upon by ABP and/or ABT, and the LANDLORD. 

8.3 Unless otherwise informed by ABP in writing, the AAS biomass will be maintained at or below twenty (20) kilograms per cubic meter of grow-out tank
water volume, and the AAS biomass will be managed through selective culling and harvesting. This maximum AAS biomass may be modified in the future under mutual written agreement of ABP and/or ABT, and the LANDLORD. 

  
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 ARTICLE 9. PAYMENT 

9.1 ABP agrees to pay the LANDLORD a total fee of US$712,834.00 over the term of the lease (the FEE), such payments to be made according to article 9.2
that cover all of the costs for: 
  

	 	1.	The lease of the Parcel, which is US$13,200.00 per month of the FEE and is included in the monthly payments and the Deposit as further defined in this Agreement; 

 

	 	2.	The management services of the ABP Project; 

  

	 	3.	The operational expenses of the ABP Project; and 

  

	 	4.	The opportunity costs for loss of revenue from sales of trout to organic food wholesalers. 

 9.2 Payments to
the LANDLORD: 
 a. The first payment to the LANDLORD will be a $180,000.00 Deposit that the LANDLORD will acknowledge in writing upon
receipt by means of a letter that shall be personally delivered to ABP; and by email, as well; 
 b. Monthly payments numbers one
(1) through twelve (12) will be $15,000.00 per month for October 2013 through September 2014; 
 c. Monthly payment number thirteen
(13) will be $22,834.00 for October 2014; and 
 d. Monthly payments number fourteen (14) through twenty-four (24) will be
$30,000.00 per month for November 2014 through September 2015. 
 9.3 The FEE shall be transferred to the following bank account designated by the LANDLORD
within the first ten (10) days of every month: 
 CITIBANK NEW YORK 

ABA ######### (Swift: ###### ## ) 
 Credit to account No. ########

 In name of GLOBAL BANK CORPORATION (Swift: GLBLPAPA ) 
 For
further credit to account No. ##-###-#####-# 
 In the name of: LUIS LAMASTUS 

9.4 The LANDLORD agrees to pay all operational expenses related to the ABP Project from the FEE, excluding (i) the AAS eggs; and (ii) the
freight costs associated with the Shipment of the AAS eggs from Canada to Panama. 
 9.5 The monthly payment described in section 9.1 will be suspended if
the total live AAS population in the ABP Project’s rearing facilities falls below one hundred (100) AAS, for any reason other than programmed harvests mutually agreed upon by both, ABT by means of ABP, and the LANDLORD. In the event that
the AAS population in the rearing facilities has not recovered to more than one hundred (100) AAS within ninety (90) days of falling below the one hundred (100) AAS threshold, this agreement will be irrevocably terminated without the
need of previous notice or judicial authorization, unless it is remedied within the cure period stated in Article 12 of this Agreement. 

  
 -6- 

 In the event that the loss of AAS is due to an Act of God (caso fortuito as described in the second
paragraph of Article 34-D of the Civil Code of Panama) or a government imposed action (fuerza mayor as described in the first paragraph of Article 34-D of the Civil Code of Panama), that was not directly or indirectly caused by the LANDLORD,
the monthly payments will continue at fifty percent (50%), which is US$15,000.00 per month, until the termination date of this Agreement. 
 In the event
that the conditions of 9.5 have been triggered by loss of AAS as described above within the first thirteen (13) months of the TERM, the reduced monthly payments of $15,000.00 described above will be discounted (up to a maximum of $15,000 per
month) until the Deposit has been fully realized, at which point the $15,000.00 per month payments to the LANDLORD will continue until the termination date of the Agreement. 

9.6 ABP will pay for an independent local auditor to prepare an inventory of the AAS population in the ABP Project and to verify that no material changes have
been made to the ABP Project’s layout, production facilities, containment elements, and water distribution pathways. 
 9.7 In the event that
Panamanian legal counsel is required to defend the ABP Project against litigations or claims, ABP will assume the legal expenses if the litigation or claim arises out of (i) reasons not attributable to the LANDLORD; and/or (ii) reasons
attributable to the ABP Project or the AAS eggs. However, if the litigation or claim is a result of a direct or indirect action of the LANDLORD, then the LANDLORD will bear said legal expenses. 

9.8 ABP will transfer ownership to the LANDLORD of ABP’s vehicle (2007 Nissan Frontier, license plate: 416101) at no cost to the LANDLORD. 

ARTICLE 10. PRODUCT 
 10.1 Product
ownership: ABP is the owner of (i) the AAS contained in the tanks; and (ii) the harvested AAS. At its discretion, ABP may offer without any cost to the LANDLORD a portion of the AAS as a production performance incentive bonus, in
addition to the monthly fees described in Article 9.1, if the AAS has been approved by United States (U.S.) and Panamanian authorities as described in Article 11. 

10.2 Product sales: In the event that the AAS is approved by U.S. and the authorities of the Republic of Panama, as described in Article 11, ABP,
and/or ABT, will determine to whom and in what form the harvested AAS will be commercialized. The LANDLORD will be given first rights of refusal to purchase the harvested AAS. 

10.3 Product processing: ABT and/or ABP will decide where to process the harvested AAS. If ABT and/or ABP use the LANDLORD to process the AAS, ABT
and/or ABP will pay the LANDLORD a competitively priced processing and packing fee that shall be agreed by both parties. 
 10.4 Sales Proceeds: In
the event that the AAS is approved by the U.S. and authorities of the Republic of Panama, as described in Article 11, all sales proceeds from approved harvested AAS will belong to ABP and/or ABT. 

  
 -7- 

 ARTICLE 11. PRODUCT DISPOSITION 

Until the U.S. FDA has approved AAS in the U.S., and until ABP has complied with the regulations and laws of the Republic of Panama permitting the
commercialization and consumption of AAS in Panama, all AAS produced at the ABP Project must be destroyed according to the protocol established by the authorities in Panama and not allowed to enter commerce or be consumed. 

ARTICLE 12. CURE PERIOD 
 If any of the Parties
breaches the terms of this Agreement (“Breach”), the offended party will deliver a written notice to the breaching party (“Notice”) within thirty (30) calendar days of the Breach. The breaching party will in turn have sixty
(60) calendar days to remedy his Breach (“Cure Period”). In the event that breaching party does not satisfactorily remedy his Breach within the Cure Period, the offended party shall have the right to terminate this Agreement by
written notice to the breaching party. Notwithstanding the above, shall according to the exclusive opinion of ABP, the Breach endanger the ABP Project, upon Notice the LANDLORD will be obliged to immediately remedy the Breach, and shall it not be
remedied, ABP will be entitled to terminate this Agreement without Notice and/or judicial authorization. 
 ARTICLE 13. TERMINATION 

13.1 The occurrence of any of the following events shall be deemed to be and shall be treated as a default under this Agreement and the parties shall be
entitled to terminate this Agreement without the need of Notice and/or judicial authorization: 
  

	 	1.	The breach or failure by either Party in the due observance or performance of the obligations of this Agreement; 

  

	 	2.	The extinction of the possessory rights of LANDLORD over the Property, unless that such possessory rights evolve into property rights and title; 

 

	 	3.	The resignation or death of the LANDLORD; 

  

	 	4.	The diminishment of the River Flow and/or spring water adjacent to the Parcel in such a manner that could impede ABP to continue developing its activities and/or the ABP Project; 

 

	 	5.	The expiration of the Term of this Agreement; and 

  

	 	6.	If either of the Parties files or have filed a petition of bankruptcy liquidation or dissolution. 

ARTICLE 14. CONFLICT RESOLUTION 
 In case
any disputes arise in connection with the interpretation or execution of this Agreement, such dispute shall be submitted to arbitration in law, at a proceeding administered by the Centro de Conciliación y Arbitraje de la Cámara de
Comercio, Industria y Agricultura of the Republic of Panama, to which rules the Parties unconditionally voluntarily submit and claim knowledge thereof. The dispute shall be resolved in accordance with Panamanian substantive rules and the
procedural rules of the Centro de Conciliación y Arbitraje de la Cámara de Comercio, Industria y Agricultura of the Republic of Panama or, in its defect, applicable procedural rules under Panamanian law. The arbitration shall
take place in Panama City, Republic of Panama and proceedings shall be in Spanish unless the Parties to the dispute agree otherwise. The dispute will be resolved by a panel of three arbitrators. Each Party to the dispute shall appoint an arbitrator
from the list of arbitrators approved by the Centro de Conciliación y Arbitraje de la 

  
 -8- 

 
Cámara de Comercio, Industria y Agricultura of the Republic of Panama. The Centro de Conciliación y Arbitraje de la Cámara de Comercio, Industria y Agricultura
of the Republic of Panama shall appoint the third arbitrator who will preside the panel. The award rendered pursuant to such arbitration shall be in writing, shall be final, binding and conclusive between the Parties. The award shall have no further
recourse, except for those provided for annulment in accordance with the laws of Panama. Once the award is rendered and is final, it will produce the effects of res judicata and the Parties shall comply with the award without delay. 

All costs and expenses related to the arbitration proceeding shall be borne by the Parties to the dispute in equal parts. Each party will cover the costs of
its own legal counsel and expert witnesses, except they expressly agree otherwise or the arbitrators so decide in the final award. 
 ARTICLE 15.
TAXES 
 The LANDLORD shall maintain the Property in good standing from any applicable fees or taxes from any public or private institutions. 

ARTICLE 16. GOVERNING LAW 
 This Agreement shall be
interpreted and enforced in accordance with the laws of the Republic of Panama. 
 ARTICLE 17. ENTIRE .AGREEMENT. 

This Agreement constitutes the entire Agreement between the Parties related to the subject matter herein, and the terms included herein may not be contradicted
by evidence of any prior Agreement or of any oral Agreement. 
 ARTICLE 18. NOTICES 

Any notice or written communications required or submitted under this Agreement shall be sent to the Following Addresses: 

For ABP: 
  

			
	Name:	  	David A. Frank
	Domicile:	  	Two Clock Tower Place, Suite 395, Maynard, MA 01754
	Telephone:	  	(978) 648-6048
	Email:	  	dfrank@aquabounty.com

 For the LANDLORD: 
  

			
	Name:	  	Luis Lamastus
	Domicile:	  	Los Naranjos, Boquete, Chiriqui, Panama
	Telephone:	  	507 66174739
	Email:	  	luitolamastus@hotmail.com

 ARTICLE 19. MODIFICATIONS. 

This Agreement can be only modified by written agreement of the Parties. No change in, addition to, or waiver of any of the terms and conditions of this
Agreement shall be binding upon any Party unless approved by it in writing. 

  
 -9- 

 ARTICLE 20. ASSIGNMENT. 

The Parties to this Agreement shall not assign any rights or obligations hereunder without the express written consent of the other Party. 

ARTICLE 21. SEVERABILITY 
 If it is determined that
any provision of this Agreement is invalid or not binding, in whole or in part, such invalidity shall be only in respect of that provision or portion thereof and the remainder of the same clause or all the remaining provisions of this Agreement
shall remain valid, in full force and binding on the Parties. 
 ARTICLE 22. CONFIDENTIALITY 

The Parties agree to maintain strict confidentiality of the terms of this Agreement. The Parties shall treat as confidential all information made available to
them under this Agreement and shall not disclose such confidential information without the written consent of the owner of that information. 
 The
foregoing restriction on use and disclosure shall not apply to confidential information that, at the time of disclosure or its becoming known to the recipient, the recipient can show: 

 

	 	1.	Is public knowledge; or 

  

	 	2.	Came lawfully into the recipient’s possession otherwise than directly or indirectly from the owner without restriction on its subsequent disclosure or use by the recipient. 

The foregoing restriction on use and disclosure shall be maintained by the recipient until the confidential information: 

 

	 	1.	Becomes public knowledge through no fault or action on the recipient’s part; or 

  

	 	2.	Comes into the recipient’s possession free from any restriction from a third party (other than the owner or its affiliate) who has the lawful right to make such disclosure. 

Notwithstanding the foregoing restriction on use and disclosure, a party may disclose confidential information to any competent governmental agencies having
authority to require such disclosure but informing such governmental agencies of the confidential nature of such information. 
 ARTICLE 23.
COUNTERPARTS 
 This Agreement may be executed in counterparts (and by different parties hereto in different counterparts), each of which shall
constitute an original, but all of which when taken together shall constitute a single contract. This Agreement shall become effective when it shall have been executed by the Parties in their respective counterparts, and when taken together
constitute a single document. Delivery of an executed counterpart of a signature page of this Agreement by telecopy or electronic transmission shall be effective as delivery of a manually executed counterpart of this Agreement. 

  
 -10- 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the day and year first above written.

  

					
	 /s/ Luis Lamastus
	 		 	 /s/ David Frank

	 LUIS LAMASTUS
 LANDLORD
	 		 	 DAVID FRANK
 AQUA BOUNTY PANAMA S. DE
R.L.

  
 -11-

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