Document:

THE SECURITIES  REPRESENTED BY THIS WARRANT MAY NOT BE OFFERED FOR SALE, SOLD OR
OTHERWISE  TRANSFERRED  EXCEPT PURSUANT TO AN EFFECTIVE  REGISTRATION  STATEMENT
FILED UNDER THE SECURITIES ACT OF 1933, AS AMENDED,  OR PURSUANT TO AN EXEMPTION
FROM REGISTRATION UNDER SUCH ACT.

Void after 5:00 P.M., New York Time, on December 31, 2002

                                                          Warrant to Purchase
                                                          _________ Shares of
                                                          Common Stock

                CLASS C REDEEMABLE COMMON STOCK PURCHASE WARRANT

                  This Is to Certify That, FOR VALUE RECEIVED,

                               -------------------

is entitled to purchase,  subject to the provisions of this Warrant, from SELECT
THERAPEUTICS,  INC. (the "Company"),  a Delaware corporation,  at any time on or
after April 1, 2000 (the  "effective  date"),  and not later than 5:00 P.M., New
York time, on December 31, 2002,  _________________  (________) shares of Common
Stock of the Company at a purchase price per share of $2.00; provided,  however,
that the number of shares of Common  Stock to be received  upon the  exercise of
this  Warrant  and the  price to be paid for a share of  Common  Stock  shall be
adjusted form time to time as hereinafter set forth.  The shares of Common Stock
deliverable  upon  such  exercise,  and as  adjusted  from  time  to  time,  are
hereinafter  sometimes  referred to as "Warrant Stock" and the exercise price of
this  Warrant  in  effect  at any  time  and as  adjusted  from  time to time is
hereinafter  sometimes  referred to as the  "Exercise  Price".  The  above-named
registered owner of this Warrant and its permitted  transferees and/or assignees
are hereinafter referred to as, collectively, the "Holder".

     (a) Exercise of Warrant.  This Warrant may be exercised in whole or in part
at any time or from time to time on or after the effective  date,  but not later
than 5:00 P.M., New York time, on December 31, 2002, or if such  expiration date
is a day on which banking  institutions are authorized by law to close,  then on
the next  succeeding  day which  shall not be such a day,  by  presentation  and
surrender  hereof to the Company  with the  Purchase  Form  annexed  hereto duly
executed  and  accompanied  by payment of the  Exercise  Price for the number of
shares of Warrant  Stock  specified in such form,  together with all federal and
state taxes  applicable upon such exercise.  If this Warrant should be exercised
in part only,

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the Company shall, upon surrender of this Warrant for cancellation,  execute and
deliver a new warrant evidencing the right of the Holder to purchase the balance
of the Warrant Stock purchasable hereunder.  At the close of business on the day
of  receipt  by the  Company  of this  Warrant  at the  office  or agency of the
Company, in proper form for exercise and accompanied by payment as aforesaid for
the Warrant Stock to be acquired, the Holder shall be deemed to be the holder of
record of the number of fully  paid and  non-assessable  shares of Common  Stock
issuable upon such  exercise,  notwithstanding  that the stock transfer books of
the Company shall then be closed or that  certificates  representing such shares
of Common Stock shall not then actually be delivered to the Holder.

     (b)  Reservation  of Shares.  The Company  hereby  agrees that at all times
there shall be reserved  for  issuance  and/or  delivery  upon  exercise of this
Warrant  such  number of shares of its  Common  Stock as shall be  required  for
issuance or delivery upon exercise of this Warrant.

     (c)  Fractional   Shares.  No  fractional  shares  or  scrip   representing
fractional  shares  shall be issued  upon the  exercise  of this  Warrant.  With
respect to any  fraction of a share  called for upon any  exercise  hereof,  the
Company  shall  pay to the  holder  an  amount  in cash  equal to such  fraction
multiplied by the current market value of such fractional  share,  determined as
follows:

          (1) If the Common Stock is listed on a national securities exchange or
     admitted to unlisted trading privileges on such exchange, the current value
     shall be the last reported sales price of the Common Stock on such exchange
     on the last trading day prior to the date of exercise of this  Warrant,  or
     if no such  sale is made on such day,  the  average  closing  bid and asked
     prices for such day on the composite tape of such exchange; or

          (2) If the  Common  Stock is not so listed  or  admitted  to  unlisted
     trading  privileges,  the  current  value  shall  be the  mean of the  last
     reported  bid and asked  prices  reported by the  National  Association  of
     Securities  Dealers  Automated  Quotation  System  ("NASDAQ")  (or,  if not
     reported by NASDAQ,  then reported by the National Quotation Bureau,  Inc.)
     on the last trading day prior to the date of the exercise of this  Warrant;
     or

          (3) If the  Common  Stock is not so listed  or  admitted  to  unlisted
     trading  privileges  and bid and  asked  prices  are not so  reported,  the
     current  value shall be an amount,  not less than fully diluted book value,
     determined in such  reasonable  manner as may be prescribed by the Board of
     Directors of the Company, such determination to be final and binding on the
     Holder.

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<PAGE>

     (d) Exchange,  Assignment or Loss of Warrant. This Warrant is exchangeable,
without expense,  at the option of the Holder,  upon  presentation and surrender
hereof to the Company or at the office of its stock transfer  agent, if any, for
other  Warrants  of  different  denominations  entitling  the Holder  thereof to
purchase  in  the  aggregate  the  same  amount  of  Warrant  Stock  purchasable
hereunder. Any such assignment shall be made by surrender of this Warrant to the
Company  or at the  office  of its  stock  transfer  agent,  if  any,  with  the
Assignment  Form annexed  hereto duly  executed and funds  sufficient to pay any
transfer tax; whereupon the Company shall, without charge, execute and deliver a
new Warrant in the name of the assignee  named in such  instrument of assignment
and this Warrant  shall  promptly be  cancelled.  This Warrant may be divided or
combined  with other  Warrants  which carry the same  rights  upon  presentation
hereof  at the  office of the  Company  or at the  office of its stock  transfer
agent,  if  any,  together  with a  written  notice  specifying  the  names  and
denominations in which new Warrants are to be issued. The term "Warrant" as used
herein includes any Warrants  issued in substitution  for or replacement of this
Warrant, or into which this Warrant may be divided or exchanged. Upon receipt by
the Company of evidence  satisfactory to it of the loss,  theft,  destruction or
mutilation of this Warrant,  and (in the case of loss,  theft or destruction) of
indemnification  reasonably  satisfactory  in form and substance to its counsel,
and upon surrender and cancellation of this Warrant,  if mutilated,  the Company
will  execute  and  deliver a new  Warrant of like tenor and date.  Any such new
Warrant  executed and  delivered  shall  constitute  an  additional  contractual
obligation  on the part of the  Company,  whether  or not this  Warrant so lost,
stolen, destroyed, or mutilated, shall be at any time enforceable by anyone.

     (e) Rights of the  Holder.  The  Holder  shall not,  by virtue  hereof,  be
entitled  to any rights of a  shareholder  of the  Company,  either at law or in
equity,  and the  rights of the Holder are  limited to those  expressed  in this
Warrant and are not  enforceable  against  the Company  except to the extent set
forth herein.

     (f) Anti-Dilution Provisions.

          (1) Stock  Dividends,  Subdivisions and  Combinations.  If the Company
     shall  at  any  time  issue  Common  Stock  by  way of  dividend  or  other
     distribution  on the Common Stock of the  Company,  or subdivide or combine
     the  outstanding  shares of Common Stock,  then the Exercise Price shall be
     proportionately  decreased  in the  case  of  such  issuance  (on  the  day
     following the date fixed for determining  shareholders  entitled to receive
     such dividend or

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<PAGE>

     other  distribution)  or  decreased  in the  case  of such  subdivision  or
     increased  in  the  case  of  such  combination  (on  the  date  that  such
     subdivision or combination shall become effective).  Upon any adjustment of
     the  Exercise  Price  pursuant to this Section  (f)(1),  the holder of this
     Warrant shall  thereafter  (until  another such  adjustment) be entitled to
     purchase,  at  the  new  Exercise  Price,  the  amount  of  Warrant  Stock,
     calculated to the nearest full share, obtained by multiplying the number of
     shares of Warrant  Stock then issuable upon exercise of this Warrant by the
     Exercise  Price then in effect and  dividing the product so obtained by the
     new Exercise Price.

          (2) No Adjustment for Small  Amounts.  Anything in this Section (f) to
     the  contrary  notwithstanding,  the Company  shall not be required to give
     effect to any  adjustment  in the  Exercise  Price unless and until the net
     effect of one or more adjustments, determined as above provided, shall have
     required a change of the  Exercise  Price by at least five  percent in such
     Price,  but when the  cumulative  net effect of more than one adjustment so
     determined  shall be to change the actual  Exercise  Price by at least five
     percent, such change in the Exercise Price shall thereupon be given effect.

          (3) Common Stock Defined.  Whenever  reference is made in this Section
     (f) to the issue or sale of shares of Common Stock, the term "Common Stock"
     shall mean the Common  Stock of the Company of the class  authorized  as of
     the date hereof and any other class of stock  ranking on a parity with such
     Common  Stock.  However,  subject to the  provisions of Section (i) hereof,
     shares issuable upon exercise hereof shall include only shares of the class
     designated as Common Stock of the Company as of the date hereof.

     (g) Officer's Certificate. Whenever the Exercise Price shall be adjusted as
required by the  provisions of Section (f) hereof,  the Company shall  forthwith
file in the custody of its Secretary or an Assistant  Secretary at its principal
office,  and with its stock  transfer  agent,  if any, an officer's  certificate
showing the adjusted  Exercise Price  determined as herein  provided and setting
forth in reasonable detail the facts requiring such adjustments.  Each officer's
certificate  shall be made available at all  reasonable  times for inspection by
the Holder, and the Company shall, forthwith after each such adjustment,  mail a
copy of such certificate to the Holder.  Such certificate shall be conclusive as
to the correctness of such adjustment.

     (h)  Notices  to  Warrant  Holders.  So  long  as  this  Warrant  shall  be
outstanding and unexercised, (i) if the Company shall pay

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<PAGE>

any  dividend  or make any  distribution  upon the Common  Stock to the  holders
thereof as a group in proportion to their respective  shareholdings,  or (ii) if
the Company shall offer to the holders of Common Stock, as a group in proportion
to their  respective  shareholdings,  for  subscription  or purchase by them any
shares  of  stock of any  class or any  other  rights,  or (iii) if any  capital
reorganization  of the  Company,  reclassification  of the capital  stock of the
Company, consolidation or merger of the Company with or into another corporation
(other  than a merger in which the  Company is the  continuing  corporation  and
which does not result in any reclassification,  capital  reorganization or other
similar change of outstanding  shares of Common Stock of the class issuable upon
exercise of this Warrant),  sale, lease or transfer of all or substantially  all
of the property and assets of the Company to another  corporation,  or voluntary
or  involuntary  dissolution,  liquidation or winding up of the Company shall be
effected, then, in any such case, the Company shall cause to be delivered to the
Holder,  at least ten days prior to the date  specified in (x) or (y) below,  as
the case may be, a notice  containing a brief description of the proposed action
and  stating  the date on which (x) a record is to be taken for the  purpose  of
such  dividend,   distribution   or  rights,   or  (y)  such   reclassification,
reorganization,   consolida-  tion,  merger,  conveyance,   lease,  dissolution,
liquidation or winding up is to take place and the date, if any, as of which the
holders of Common Stock of record shall be entitled to exchange  their shares of
Common  Stock  for   securities  or  other   property   deliverable   upon  such
reclassification,    reorganization,    consolidation,    merger,    conveyance,
dissolution, liquidation or winding up.

     (i)   Reclassification,   Reorganization   or   Merger.   In  case  of  any
reclassification,  capital  reorganization or other change of outstanding shares
of  Common  Stock of the  Company  (other  than a change  in par value or to par
value, or as a result of an issuance of Common Stock by way of dividend or other
distribution  or  of  a  subdivision  or   combination),   or  in  case  of  any
consolidation or merger of the Company with or into another  corporation  (other
than a merger in which the Company is the continuing  corporation and which does
not result in any  reclassification,  capital  reorganization  or other  similar
change of outstanding shares of Common Stock of the class issuable upon exercise
of this Warrant),  or in case of any sale or conveyance to any other corporation
of the property and assets of the Company as an entirety or  substantially as an
entirety,  the Company  shall cause  effective  provision to be made so that the
Holder shall have the right thereafter,  by exercising this Warrant, to purchase
the kind and amount of shares of securities and other property  receivable  upon
such reclassification, capital reorganization or other similar

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<PAGE>

change, consolidation, merger, sale or conveyance as if the Holder had exercised
this  Warrant  prior to such  transaction.  Any  such  provision  shall  include
provision  for  adjustments  which  shall  be as  nearly  equivalent  as  may be
practicable  to the  adjustments  provided for in this  Warrant.  The  foregoing
provisions   of  this   Section  (i)  shall   similarly   apply  to   successive
reclassifications,  capital  reorganizations  and  similar  changes of shares of
Common Stock and to successive consolidations, mergers, sales or conveyances.

     (j)  Spin-Offs.  In  the  event  the  Company  spins-off  a  subsidiary  by
distributing to the shareholders of the Company, as a dividend or otherwise, the
stock of the subsidiary, the Company shall reserve, for the life of the Warrant,
shares of the  subsidiary  to be  delivered  to the Holder upon  exercise of the
Warrant to the same  extent as if Holder was the owner of record of the  Warrant
Stock on the record date for payment of the shares of the subsidiary.

     (k) "Piggyback" Registration Rights.

          (1)  Definitions.  As used in this Section (k),  the  following  terms
     shall have the following meanings:

               (a) The term "Holder"  shall mean any person owning or having the
          right to acquire Registrable Securities or any permitted transferee of
          a Holder.

               (b) The terms "register",  "registered" and "registration"  refer
          to a  registration  effected by  preparing  and filing a  registration
          statement or similar document  (except a Registration  Statement filed
          for a purpose  which would render  inappropriate  the covenants of the
          Company contained in this Section (k) such as a Registration Statement
          on Form S-8 or any other  inappropriate  form), in compliance with the
          Securities  Act of 1933, as amended (the  "Securities  Act"),  and the
          declaration or order of effectiveness of such  registration  statement
          or document.

               (c) The term  "Registrable  Securities"  shall  mean the  Warrant
          Stock;  provided,  however,  that securities  shall only be treated as
          Registrable  Securities  if and  only for so long as they (A) have not
          been  disposed  of  pursuant  to  a  registration  statement  declared
          effective by the Securities and Exchange Commission ("SEC"),  (B) have
          not  been  sold in a  transaction  exempt  from the  registration  and
          prospectus  delivery  requirements  of the  Securities Act wherein all
          transfer restrictions and restrictive legends with respect thereto are
          removed  upon  the  consummation  of such  sale  and (C) are held by a
          Holder or a  permitted  transferee  of a Holder  pursuant  to  Section
          (k)(10) below.

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<PAGE>

          (2) Registration under the Securities Act.

               (a) In the event that at any time  before the second  anniversary
          of the effective date of this Warrant the Company  intends to register
          securities  which relate to a current  offering of  securities  of the
          Company,  the Company shall give written notice (the "Company Notice")
          of such intention to the Holder, and upon receipt within 30 days after
          the giving of the Company Notice of the written request of the Holder,
          the  Company  shall  include  in  such  registration  the  Registrable
          Securities  of the Holder so as to permit the public  sale  thereof by
          the Holder in compliance with the Securities Act. Neither the delivery
          of a Company Notice nor of a registration  request by any Holder shall
          in any way obligate the Company to file such  Registration  Statement.
          Notwithstanding  the filing of the Registration  Statement the Company
          may, at any time prior to the effective date thereof, determine not to
          offer the  securities  to which it relates,  without  liability to the
          Holder  except that the Company  shall pay such  expenses as are to be
          paid by it under Section (k)(5).

               (b) In no event shall the Company be  obligated to file more than
          one registration  statement for the subject Registrable  Securities on
          account of the registration rights granted to the Holders thereof.

          (3) Obligations of the Company.  Whenever  required under this Section
     (k) to include  Registrable  Securities in a  registration  statement,  the
     Company shall, as expeditiously as reasonably possible:

               (a) Use its  reasonable  best efforts to cause such  registration
          statement to become effective, and, upon the request of the Holders of
          a majority of the Registrable Securities registered  thereunder,  keep
          such registration  statement  effective for a period of up to 120 days
          or until the distribution  contemplated in the Registration  Statement
          has been  completed  and,  during  the period  that such  registration
          statement  is  required  to  be   maintained   hereunder,   file  such
          post-effective  amendments and supplements  thereto as may be required
          by the  Securities  Act and the rules and  regulations  thereunder  or
          otherwise  to ensure that the  prospectus  included  therein  does not
          contain any untrue  statement of material fact or omit to state a fact
          required  to be stated  therein or  necessary  to make the  statements
          contained therein,  in light of the circumstances under which they are
          made,  not  misleading;  provided,  however,  that such 120-day period
          shall be  extended  for a period of time equal to the period  that the
          Holder   refrains  from  selling  any  securities   included  in  such
          registration  at the  request of an  underwriter  of Common  Stock (or
          other

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<PAGE>

securities) of the Company,  and provided further that if applicable rules under
the Securities Act governing the obligation to file a  post-effective  amendment
permit,  in lieu of filing a  post-effective  amendment  that (i)  includes  any
prospectus  required by Section  10(a)(3) of the Securities Act or (ii) reflects
facts or events representing a material or fundamental change in the information
set  forth  in the  registration  statement,  the  Company  may  incorporate  by
reference  information  required  to be  included  in (i) and (ii)  above to the
extent such  information  is contained  in periodic  reports  filed  pursuant to
Section 13 or 15(d) of the  Securities  Exchange  Act of 1934,  as amended  (the
"Exchange Act"), in the registration statement.

               (b) Prepare and file with the SEC such amendments and supplements
          to such registration statement,  and the prospectus used in connection
          with such registration  statement,  as may be necessary to comply with
          the provisions of the  Securities Act with respect to the  disposition
          of all securities covered by such registration statement.

               (c)  Furnish  to  the  Holders   such  numbers  of  copies  of  a
          prospectus,   including  a   preliminary   prospectus  as  amended  or
          supplemented from time to time, in conformity with the requirements of
          the  Securities  Act, and such other  documents as they may reasonably
          request  in  order  to  facilitate  the   disposition  of  Registrable
          Securities owned by them.

               (d) Use its  reasonable  best efforts to register and qualify the
          Registrable  Securities  covered by such registration  statement under
          such other federal or state  securities laws of such  jurisdictions as
          shall be reasonably requested by the Holders; provided,  however, that
          the  Company  shall not be required in  connection  therewith  or as a
          condition  thereto  to  qualify  to do  business  or to file a general
          consent to service  of  process in any such  states or  jurisdictions,
          unless the Company is already subject to service in such  jurisdiction
          and except as may be required by the Securities Act.

               (e) In the event of any underwritten public offering,  enter into
          and perform its obligations under an under writing agreement, in usual
          and customary  form,  with the managing  underwriter of such offering.
          Each Holder  participating in such underwriting  shall also enter into
          and perform its obligations under such an agreement.

               (f) At  any  time  when  a  prospectus  relating  to  Registrable
          Securities  covered by such  registration  statement is required to be
          delivered under the Securities Act, notify each

                                        8
<PAGE>

          Holder  (i)  when the  registration  statement  or any  post-effective
          amendment and  supplement  thereto has become  effective,  (ii) of the
          issuance by the SEC of any stop order or the initiation of proceedings
          for that  purpose (in which event the Company  shall make every effort
          to obtain the withdrawal of any order suspending  effectiveness of the
          registration  statement at the earliest  possible  time or prevent the
          entry   thereof),   (iii)  of  the  receipt  by  the  Company  of  any
          notification  with respect to the suspension of the  qualification  of
          the  Registrable  Securities  for  sale  in  any  jurisdiction  or the
          initiation  of  any  proceeding  for  such  purpose  and  (iv)  of the
          happening of any event as a result of which the prospectus included in
          such  registration  statement,  as then in effect,  includes an untrue
          statement  of a  material  fact or  omits  to  state a  material  fact
          required  to be stated  therein or  necessary  to make the  statements
          therein  not  misleading  in  the  light  of  the  circumstances  then
          existing.

               (g) Cause all such Registrable Securities registered hereunder to
          be listed on each  securities  exchange or quotation  service on which
          similar securities issued by the Company are then listed or quoted.

               (h) Provide a transfer  agent and registrar  for all  Registrable
          Securities  registered  hereunder  and a CUSIP  number  for  all  such
          Registrable Securities, in each case not later than the effective date
          of such registration.

     (4) Holders'  Obligation  to Furnish  Information.  It shall be a condition
precedent to the  obligation of the Company to take any action  pursuant to this
Section (k) with respect to the  Registrable  Securities  of any selling  Holder
that such Holder shall  furnish to the Company such  information  regarding  the
Holder,  the Registrable  Securities held by the Holder, and the intended method
of disposition of such securities as shall be reasonably required by the Company
to effect the registration of such Holder's Registrable Securities.

     (5) Expenses of Piggyback Registration.  The Company shall bear and pay all
expenses incurred in connection with any registration of Registrable  Securities
pursuant to Section (k)(2)(a) for each Holder,  including  (without  limitation)
all registration,  filing, and qualification  fees, printers and accounting fees
relating or  apportionable  thereto,  but excluding  underwriting  discounts and
commissions  relating to Registrable  Securities;  provided,  however,  that the
Company shall not bear the cost of any professional fees or costs of accounting,
financial or legal advisors to any of the Holders. Notwithstanding the

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foregoing,  each Holder shall pay all registration  expenses that such Holder is
required to pay under applicable law.

     (6) Underwriting Requirements. In connection with any offering involving an
underwriting of shares of the Company's  capital stock, the Company shall not be
required  under  Section  (k)(2)  to  include  any of the  Holders'  Registrable
Securities in such underwriting unless they accept the terms of the underwriting
as agreed upon  between the Company and the  underwriters  selected by it (or by
other  persons  entitled  to  select  the  underwriters),  and then only in such
quantity  as the  underwriters  determine  in  their  sole  discretion  will not
jeopardize  the success of the offering by the  Company.  If the total amount of
securities,  including Registrable Securities,  requested by selling stockholder
to be included in such  offering  exceeds  the amount of  securities  to be sold
other  than by the  Company  that  the  underwriters  determine  in  their  sole
discretion  is  compatible  with the success of the  offering,  then the Company
shall  be  required  to  include  in the  offering  only  that  number  of  such
securities,  including Registrable Securities,  which the underwriters determine
in their sole  discretion  will not  jeopardize the success of the offering (the
securities   so  included  to  be   apportioned   pro  rata  among  the  selling
stockholders, including the Holders, according to the total amount of securities
entitled to be included  therein  owned by each selling  stockholder  or in such
other proportions as shall mutually be agreed to by such selling  stockholders).
For purposes of the preceding parenthetical  concerning  apportionment,  for any
selling  stockholder  who  is  a  Holder  of  Registrable  Securities  and  is a
partnership or corporation,  the partners,  retired partners and stockholders of
such holder,  or the estates and family members of any such partners and retired
partners and any trusts for the benefit of any of the foregoing persons shall be
deemed to be a single  "selling  stockholder",  and any pro-rata  reduction with
respect to such "selling  stockholder"  shall be based upon the aggregate amount
of shares  carrying  registration  rights owned by all entities and  individuals
included in such "selling stockhold er", as defined in this sentence.

     (7) Delay of Registration. No Holder shall have any right to obtain or seek
an injunction  restraining or otherwise  delaying any such  registration  as the
result of any controversy that might arise with respect to the interpretation or
implemen tation of these Registration Rights.

     (8)  Indemnification.  In the event  that any  Registrable  Securities  are
included in a registration statement under this Section (k)(2):

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<PAGE>

               (a) To the extent  permitted by law,  the Company will  indemnify
          and hold  harmless  each Holder,  any  underwriter  (as defined in the
          Securities Act) for such Holder and each person,  if any, who controls
          such Holder or underwriter within the meaning of the Securities Act or
          the Exchange Act, against any losses, claims,  damages, or liabilities
          (joint  or  several)  to  which  they may  become  subject  under  the
          Securities Act, or the Exchange Act,  insofar as such losses,  claims,
          damages,  or liabilities (or actions in respect  thereof) arise out of
          or are  based  upon  any of the  following  statements,  omissions  or
          violations  (collectively a "Violation"):  (i) any untrue statement or
          alleged  untrue  statement  of  a  material  fact  contained  in  such
          registration statement,  including any preliminary prospectus or final
          prospectus contained therein or any amendments or supplements thereto,
          (ii) the omission or alleged omission to state therein a material fact
          required to be stated  therein,  or necessary  to make the  statements
          therein not misleading, or (iii) any violation or alleged violation by
          the Company of the  Securities  Act, the Exchange  Act, or any rule or
          regulation  promulgated under the Securities Act, or the Exchange Act,
          and  the  Company  will  pay  to  each  such  Holder,  underwriter  or
          controlling   person,  as  incurred,   any  legal  or  other  expenses
          reasonably  incurred  by  them in  connection  with  investigating  or
          defending  any  such  loss,  claim,  damage,   liability,  or  action;
          provided,  however,  that the  indemnity  agreement  contained in this
          Section  (k)(8) shall not apply to amounts paid in  settlement  of any
          such loss, claim, damage,  liability,  or action if such settlement is
          effected  without the consent of the Company  (which consent shall not
          be unreasonably withheld), nor shall the Company be liable in any such
          case for any such loss,  claim,  damage,  liability,  or action to the
          extent that it arises out of or is based upon a Violation which occurs
          in reliance upon and in conformity with written information  furnished
          expressly for use in  connection  with such  registration  by any such
          Holder, underwriter or controlling person.

               (b) To the extent  permitted  by law,  each  selling  Holder will
          indemnify and hold harmless the Company,  each of its directors,  each
          of its  officers  who has  signed  the  registration  statement,  each
          person,  if any, who  controls  the Company  within the meaning of the
          Securities Act, any underwriter,  any other person selling  securities
          in such registration  statement and any controlling person of any such
          underwriter or other person, against any losses,  claims,  damages, or
          liabilities  (joint or several) to which any of the foregoing  persons
          may become  subject,  under the  Securities  Act, or the Exchange Act,
          insofar as such losses, claims, damages, or liabilities (or actions in
          respect thereto) arise out of or are based upon any Violation, in each
          case to the extent (and only to the extent) that such Violation occurs

                                       11
<PAGE>

          in reliance upon and in conformity with written information fur nished
          by such Holder expressly for use in connection with such registration;
          and each  such  Holder  will  pay,  as  incurred,  any  legal or other
          expenses  reasonably incurred by any person intended to be indemnified
          pursuant to this Section (8)(b),  in connection with  investigating or
          defending  any  such  loss,  claim,  damage,   liability,  or  action;
          provided,  however,  that the  indemnity  agreement con tained in this
          Section  (8)(b) shall not apply to amounts paid in  settlement  of any
          such loss,  claim,  damage,  liability or action if such settlement is
          effected without the consent of the Holder, which consent shall not be
          unreasonably withheld; provided, that, in no event shall any indemnity
          under this Section  (8)(b) exceed the gross proceeds from the offering
          received by such Holder.

               (c) Promptly  after  receipt by an  indemnified  party under this
          Section (8) of notice of the commencement of any action (including any
          governmental  action),  such  indemnified  party shall,  if a claim in
          respect  thereof is to be made  against any  indemnifying  party under
          this Section (8), deliver to the  indemnifying  party a written notice
          of the commencement  thereof and the indemnifying party shall have the
          right to participate in, and, to the extent the indemnifying  party so
          desires, jointly with any other indemnifying party similarly notified,
          to  assume  the  defense   thereof  with   counsel   selected  by  the
          indemnifying  party  and  approved  by the  indemnified  party  (whose
          approval shall not be unreasonably withheld);  provided, however, that
          an  indemnified  party  (together with all other  indemnified  parties
          which may be represented  without  conflict by one counsel) shall have
          the right to retain one separate  counsel,  with the fees and expenses
          to be paid by the indemnifying  party, if representation of such indem
          nified party by the counsel retained by the  indemnifying  party would
          be  inappropriate  due to  actual  or  potential  differing  interests
          between such indemnified party and any other party represented by such
          counsel in such  proceeding.  The failure to deliver written notice to
          the  indemnifying  party within a rea sonable time of the commencement
          of any such  action,  if  prejudicial  to its  ability to defend  such
          action, shall relieve such indem nifying party of any liability to the
          indemnified  party  under this  Section  (8),  but the  omission so to
          deliver written notice to the  indemnifying  party will not relieve it
          of any liability that it may have to any  indemnified  party otherwise
          than under this Section (8).

               (d) If the  indemnification  provided  for in this Section (8) is
          held by a court of  competent  jurisdiction  to be  unavailable  to an
          indemnified party with respect to any loss, liability,  claim, damage,
          or expense referred to therein,  then the indemnifying  party, in lieu
          of indemnifying such indemnified party

                                       12
<PAGE>

          hereunder,  shall  contribute  to the  amount  paid or payable by such
          indemnified party as a result of such loss, liability,  claim, damage,
          or  expense  in such  proportion  as is  appropriate  to  reflect  the
          relative  fault of the  indemnifying  party on the one hand and of the
          indemnified  party on the other in connection  with the  statements or
          omissions that resulted in such loss,  liability,  claim,  damage,  or
          expense as well as any other relevant  equitable  considerations.  The
          relative fault of the indemnifying  party and of the indemnified party
          shall be determined  by reference to, among other things,  whether the
          untrue or alleged untrue  statement of a material fact or the omission
          to state a  material  fact  relates  to  information  supplied  by the
          indemnifying  party  or by the  indemnified  party  and  the  parties'
          relative intent, knowledge, access to information,  and opportunity to
          correct or prevent such statement or omission.

               (e)  Notwithstanding  the  foregoing,  to  the  extent  that  the
          provisions  on  indemnification  and  contribution  contained  in  the
          underwriting   agreement   entered   into  in   connection   with  the
          underwritten  public  offering  are in  conflict  with  the  foregoing
          provisions,   the  provisions  in  the  underwriting  agreement  shall
          control.

               (f) The obligations of the Company and Holders under this Section
          (8) shall  survive  the  completion  of any  offering  of  Registrable
          Securities  in  a  registration  statement  under  these  Registration
          Rights, and otherwise.

     (9) Reports under the Exchange Act. With a view to making  available to the
Holders  the  benefits of Rule 144 and any other rule or  regulation  of the SEC
that may at any time  permit a Holder to sell  securities  of the Company to the
public pursuant to an exemption from registration, the Company agrees to:

               (a) File with the SEC in a timely  manner all  reports  and other
          documents  required of the Company  under the  Securities  Act and the
          Exchange Act; and

               (b)  Furnish  to any  Holder,  so long  as the  Holder  owns  any
          Registrable Securities,  forthwith upon request (i) a copy of the most
          recent  annual or  quarterly  report  of the  Company  and such  other
          reports and  documents  so filed by the  Company,  and (ii) such other
          information  as may be reasonably  requested in availing any Holder of
          any rule or  regulation  of the SEC which  permits  the selling of any
          such securities without registration or pursuant to such form.

     (10)  Permitted  Transferees.  The right to cause the  Company to  register
Registrable Securities granted to the Holder by

                                       13
<PAGE>

the Company under this Warrant may be assigned in full by a Holder in connection
with a transfer by such Holder of its Registrable Securities if: (a) such Holder
gives prior written notice to the Company;  (b) such transferee agrees to comply
with the terms and provisions of this Agreement;  (c) such transfer is otherwise
in compliance with this Agreement and (d) such transfer is otherwise be effected
in accordance with applicable securities laws. Except as specifically  permitted
by this  Section  (10),  the  rights of a Holder  with  respect  to  Registrable
Securities as set out herein shall not be transferable to any other person,  and
any  attempted  transfer  shall  cause all rights of such  Holder  therein to be
forfeited.

     (11) Termination of Registration Rights. The right of any Holder to request
the filing or inclusion  in any  registration  pursuant to Section  (k)(2) shall
terminate if all  Registrable  Securities held by such Holder may immediately be
sold under Rule 144.

               (l)  Redemption  of Warrants.  Provided the closing  price of the
          Company's  Common  Stock is $3.00 or more for 10  consecutive  trading
          days,  the  Company  shall  have the  right to call the  Warrants  for
          redemption  at a price of $.001 per  Warrant at any time.  The Company
          shall give no less than 10 days written  notice of  redemption  to the
          Holders as of the date of such  notice.  Such notice  shall set a date
          not more than 90 days  after the date of the  redemption  notice  (the
          "Redemption  Date").  Upon the Redemption  Date, the Warrants shall be
          cancelled and shall thereafter be null and void and of no effect,  and
          the Company  shall pay to the Holders as of the date of the notice the
          above  redemption  price upon surrender of their Warrants.  No Warrant
          will be subject to redemption unless at the time of the giving of such
          notice the Company has an effective  registration  statement under the
          Securities Act registering its sale of the Warrant Stock.

               (m) Transfer to Comply with the Securities Act.

                    (1) This  Warrant,  or any new  warrant  issued  pursuant to
               Section (d) hereof,  or the Warrant  Stock or any other  security
               issued or  issuable  upon  exercise of this  Warrant,  may not be
               offered or sold except in conformity  with the Securities Act and
               then only against  receipt of an agreement of such person to whom
               such offer of sale is made to comply with the  provisions of this
               Section (m) with  respect to any resale or other  disposition  of
               such securities.

                                       14
<PAGE>

                    (2) The Company may cause a customary  legend for securities
               not  registered  under the Securities Act to be set forth on each
               certificate  representing  Warrant  Stock or any  other  security
               issued or issuable upon exercise of this Warrant not  theretofore
               distributed   to  the   public  or  sold  to   underwriters   for
               distribution to the public pursuant to Section (k) hereof, unless
               counsel  for  the  Company  is of  the  opinion  as to  any  such
               certificate that such legend is unnecessary.

               (n) Notices.  All notices,  requests,  claims,  demands and other
          communications hereunder shall be in writing and shall be given either
          (i) by  delivery  in person,  in which case any such  notice  shall be
          deemed to have been duly  given  upon  receipt,  or (ii) by  certified
          mail,  (postage paid and return receipt  requested),in which case said
          notice  will be deemed to have been duly  given  three (3) days  after
          such mailing, to the respective parties as follows:

                  If to the Company:

                                    Select Therapeutics, Inc.
                                    124 Mt. Auburn St., Suite 200 North
                                    Cambridge, MA 02138
                                    Attn:  Robert Bender, Chairman

                  If to Holder:

                                    ______________________

                                    ______________________

                                    ______________________

or to such other  address  as either  party may have  furnished  to the other in
writing in accordance herewith, except that notices of a change of address shall
only be effective upon receipt.

               (n)  Governing  Law.  This  Warrant  shall  be  governed  by  and
          construed  in  accordance  with  the laws of the  State  of New  York,
          without regard to the principles of conflict of laws.

               (o) No Prior  Agreements.  This  Warrant (i)  contains the entire
          agreement,   and   supersedes   all   other   prior   agreements   and
          understandings, both written and oral, between the parties hereto with
          respect to the  subject  matter  hereof,  and (ii) is not  intended to
          confer upon any other person any rights or remedies hereunder.

                                       15
<PAGE>

               (p)  Effect of  Headings.  The  section  headings  herein are for
          convenience  only and shall not affect the meaning or  construction of
          this Agreement.

                                            SELECT THERAPEUTICS, INC.

                                            By: ____________________________
                                                Robert Bender, Chairman

                CLASS C REDEEMABLE COMMON STOCK PURCHASE WARRANT

                                       16
<PAGE>

                                  PURCHASE FORM

                                             Dated ______________, 20___

     The undersigned hereby irrevocably elects to exercise the within Warrant to
the  extent  of  purchasing  _____________  shares  of  Common  Stock of  SELECT
THERAPEUTICS,  INC. and hereby makes  payment of  $__________  in payment of the
actual exercise price thereof.

                     INSTRUCTIONS FOR REGISTRATION OF STOCK

Name
     _____________________________________________________________
     (please typewrite or print in block letters)

Address
        __________________________________________________________

Signature
          ________________________________________________________

Social Security or Employer I.D. No.
                                     _____________________________

                                 ASSIGNMENT FORM

                  FOR VALUE RECEIVED,
                                      ____________________________

hereby sells, assigns and transfers unto

Name
     _____________________________________________________________
         (please typewrite or print in block letters)

Address
        __________________________________________________________

the right to purchase Common Stock, represented by this Warrant to the extent of
shares as to which right is exercisable,  and does hereby irrevocably constitute
and appoint ,  attorney,  to transfer  the same on the books of the Company with
full power of substitution in the premises.

                                                     Signature
                                                              _________________

Dated:________________, 20___

                                       17STOCK OPTION AGREEMENT

     AGREEMENT, dated as of March 2, 2000, between SELECT THERAPEUTICS INC. (the
"Company"),  a Delaware  corporation  with offices at 124 Mount  Auburn  Street,
Suite  200  North,  Cambridge,  Massachusetts,  02138,  and DAWN  VAN ZANT  (the
"Optionee"),  residing at 145 Tyee Drive, Number 1573, Point Roberts, Washington
98281.

     WHEREAS,  the Company desires to recognize the Optionee's  achievements for
the Company  and provide  additional  incentive  to the  Optionee to utilize the
Optionee's  utmost  efforts to contribute to the  Company's  future  success and
prosperity  by giving the  Optionee an  opportunity  to  purchase  shares of its
common stock (the "Common Stock"), subject to the terms and conditions set forth
in this Agreement.

     NOW, THEREFORE, the parties hereto hereby agree as follows:

1. Option  Grant.  The Company  hereby  grants to the  Optionee  the option (the
"Option") to purchase 25,000 shares (the "Optioned Shares") of Common Stock from
the Company at a price of US $4.25 per share.  The Optionee shall have the right
to exercise the Option  immediately upon the execution of this Agreement through
and including March 1, 2007. The Option may be exercised in whole at any time or
in part  from  time  to time  during  the  exercise  period  and is  subject  to
adjustment as to price and number of shares as set forth in Section 5 hereof.

<PAGE>

2. Option Exercise;  Cashless Exercise. The Option may be exercised by notice to
the Company of the intent to exercise the Option,  an  acceptable  form of which
notice is set forth as Exhibit A hereto and made a part hereof,  specifying  the
number of Optioned  Shares in respect of which the Option is being exercised and
the Option  exercise  price and  accompanied by payment for such Shares by cash,
wire transfer or a bank or certified  check payable to the order of the Company.
This Option also is  exercisable  by a broker-  dealer,  acting on behalf of the
Optionee,  if (a) such broker-dealer and the Optionee shall agree to comply with
the applicable  provisions of Section 220.3(e)(4) of Regulation T of the Federal
Reserve  Board,  (b) if the  broker-dealer  agrees to remit the Option  exercise
price to the Company out of the net sales proceeds of the Optioned  Shares being
acquired and (c) if the Company  receives  written  instructions,  signed by the
Optionee,  requesting  the Company to deliver such Shares to such broker  dealer
and  specifying  the account  into which such Shares  should be  deposited.  The
Optionee  agrees to make adequate  provision for the payment of any  withholding
taxes due upon exercise of the Option.

3. Option  Transferable Only Upon the Death of the Optionee.  During the life of
the Optionee,  the Option shall not be transferable and may be exercised only by
the Optionee;  provided, however, that in the event of the death of the Optionee
prior  to the  Expiration  Date,  the  Option,  to the  extent  not  theretofore
exercised,  shall be  exercisable  in full by the  person to whom the  Option is
transferred by will or by the applicable laws of descent and  distribution,  and
the Option shall terminate upon its expiration date and not prior to such date.

                                       -2-
<PAGE>

4. Reservation of Common Stock. During the period within which the Option may be
exercised  the  Company  shall at all times have  authorized  and  reserved  for
issuance  upon such  exercise a  sufficient  number of shares of Common Stock to
provide for its exercise. The Company agrees that its issuance of this Agreement
shall constitute full authority to its officers who are charged with the duty of
causing  the  issuance of stock  certificates  of the Company to take all action
necessary or appropriate to cause to be issued the necessary stock  certificates
for the shares of Common Stock issuable upon the proper exercise of the Option.

5. Adjustment of Option Price and Number of Optioned Shares. With respect to the
Option granted hereunder, the Option price and the number and kind of securities
purchasable  upon the exercise of the Option shall be subject to adjustment from
time to time upon the occurrence of certain events as follows:

          (a) In case the  Company  shall  (i) pay a  dividend  in shares of its
     capital stock, (ii) subdivide its outstanding shares of Common Stock, (iii)
     reduce, consolidate, or combine its outstanding shares of Common Stock into
     a smaller number of shares, or (iv) issue by reclassification of its shares
     of Common Stock any shares of Common Stock of the Company, the Option price
     in effect  immediately  prior  thereto  shall be adjusted  to that  amount,
     determined by multiplying the Option price in effect  immediately  prior to
     such date by a  fraction,  of which the  numerator  shall be the  number of
     shares of Common Stock  outstanding  on such date before  giving  effect to
     such event,  and of which the denominator  shall be the number of shares of
     Common Stock outstanding after

                                       -3-
<PAGE>

     giving effect  thereto.  An  adjustment  made pursuant to this Section 5(a)
     shall become effective retroactively,  immediately after the record date in
     the case of a dividend,  and  immediately  after the effective  date in the
     case  of  a   subdivision,   reduction,   consolidation,   combination   or
     reclassification.  Each such adjustment shall be made successively whenever
     any such effective date or record date shall occur.

          (b) If the Common Stock issuable upon the exercise of the Option shall
     be changed  into the same or a  different  number of shares of any class or
     classes of stock,  whether by capital  reorganization,  reclassification or
     otherwise  (other  than a  subdivision  or  combination  of shares or stock
     dividend,  or a  reorganization,  merger,  consolidation  or sale of assets
     provided for in this Section 5), then, and in each such event, the Optionee
     shall  have  the  right  thereafter  to  receive,  without  payment  of any
     additional  consideration therefor, the kind and amount of shares of Common
     Stock and other securities  properly  receivable upon such  reorganization,
     reclassification  or other  change by  holders  of the  number of shares of
     Common Stock into which the Option might have been exercised, as reasonably
     determined by the Company's Board of Directors,  immediately  prior to such
     reorganization,   reclassification   or  change,  all  subject  to  further
     adjustment as provided in this Section 5.

          (c) If at any  time or from  time to time  there  shall  be a  capital
     reorganization of the Common Stock (other than a subdivision,  combination,
     reclassification or exchange of shares provided for in this Section 5) or a
     merger or consolidation of the Company with or into another corporation, or
     the sale of all or substantially all of the Company's properties and assets
     to any

                                       -4-
<PAGE>

     other person, then, as a part of such reorganization, merger, consolidation
     or sale, provision shall be made as reasonably  determined by the Company's
     Board of  Directors so that the Optionee  shall  thereafter  be entitled to
     receive  upon  exercise of the Option,  without  payment of any  additional
     consideration  therefor,  the  number of shares of  capital  stock or other
     securities  or  property  of the  Company or of the  successor  corporation
     resulting from such merger or  consolidation  or sale, to which a holder of
     Common  Stock  deliverable  upon  exercise  of the  Option  would have been
     entitled on such capital reorganization, merger, consolidation or sale.

          (d) Upon each adjustment in the Option price,  the number of shares of
     Common Stock purchasable  hereunder shall be adjusted, to the nearest whole
     share to the  product  obtained,  by  multiplying  the  number of shares of
     Common Stock purchasable immediately prior to such adjustment in the Option
     price by a  fraction,  the  numerator  of which  shall be the Option  price
     immediately  prior to such adjustment and the denominator of which shall be
     the Option price immediately thereafter.

          (e) The adjustments  provided for in this Section 5 are cumulative and
     shall   apply   to   successive   divisions,   subdivisions,    reductions,
     combinations,   consolidations,   issues,  distributions  or  other  events
     contemplated  herein  resulting in any  adjustment  under the provisions of
     this  Section  5;  provided,   however,  that,  notwithstanding  any  other
     provision  of this  Section 5, no  adjustment  of the Option price shall be
     required  if (1) the issue of Common  Stock is being made  pursuant  to any
     stock option or stock purchase plan in force from time to time for officers
     and/or employees of the Company, or any other option(including warrants)

                                       -5-
<PAGE>

     outstanding  at the date of  issuance  of this  Option or (2)  unless  such
     adjustment  would require an increase or decrease of more than five percent
     (5%) in the Option  price then in effect;  and provided  further,  however,
     that any  adjustments in the Option price,  which by reason of this Section
     5(e),  are not required then to be made shall be carried  forward and taken
     into account in any subsequent adjustment.

6. Certificate of Adjustment. Whenever the Option price is adjusted, as provided
in  Section 5 above,  the  Company  shall  promptly  deliver  to the  Optionee a
certificate of the principal  financial officer of the Company setting forth the
Option price after such  adjustment  and setting forth a brief  statement of the
facts requiring such adjustments and the calculation thereof.

7. No Fractional  Shares. No fractional shares of Common Stock will be issued in
connection  with any exercise of the Option.  In lieu of any  fractional  shares
which would  otherwise  be  issuable,  the  Company  shall pay cash equal to the
product of such fraction multiplied by the Option price in effect on the date of
exercise.

8.  Notice of Certain  Events.  If at any time prior to the  expiration  or full
exercise of the Option,  the Company shall:

          (a) Take a record of the  holders  of any class of  securities  of the
     Company for the purpose of determining the holders thereof who are entitled
     to receive any dividend (other than a cash dividend at the same rate as the
     rate of the last cash dividend theretofore paid) or other distribution,  or
     any rights to subscribe  for,  purchase or otherwise  acquire any shares of
     capital

                                       -6-
<PAGE>

     stock of any class or any other  securities or property,  or to receive any
     other right;

          (b) Offer for  subscription pro rata to holders of Common Stock of the
     Company  any  additional  shares  of  capital  stock of any  class or other
     rights;

          (c)  Propose  any  capital   reorganization   of  the   Company,   any
     reclassification or recapitalization of the capital stock of the Company or
     any  consolidation  or  merger  of the  Company  with,  or  sale  of all or
     substantially  all  of its  assets  to,  another  corporation  or  business
     organization; or

          (d) Be  the  subject  of any  voluntary  or  involuntary  dissolution,
     liquidation or winding-up;
     then,  in each such event,  the Company shall mail to the Optionee a notice
     specifying  (i) the date or expected date on which any such record is to be
     taken for the purpose of such dividend, distribution or right, and (ii) the
     date or expected date upon which any such reorganization, reclassification,
     recapitalization,  dissolution,  liquidation,  winding-up or offering is to
     take place and the time,  if any,  to be fixed,  as of which the holders of
     record of Common Stock shall be entitled to exchange their shares of Common
     Stock   for   securities   or  other   property   deliverable   upon   such
     reorganization,     reclassification,     recapitalization,    dissolution,
     liquidation or winding-up.  Such notice shall be mailed at least forty-five
     (45) days prior to the  earlier of the dates  specified  in clauses (i) and
     (ii) above.

                                       -7-
<PAGE>

9. Rights as a Stockholder.

     (a) The Optionee  shall not be deemed for any purposes to be a  stockholder
of the Company with respect to any of the Optioned  Shares  except to the extent
that the Option shall have been duly exercised with respect thereto.

     (b) The  existence  of an Option  shall not  affect in any way the right or
power  of the  Company  or its  stockholders  to  make or  authorize  any or all
adjustments, recapitalization, reorganizations or other changes in the Company's
capital  structure  or its  business,  or any  merger  or  consolidation  of the
Company, or any issue of bonds, debentures,  preferred or prior preference stock
ahead of or affecting the Common Stock or the rights thereof,  or dissolution or
liquidation  of the  Company or any sale or  transfer  of all or any part of its
assets or  business,  or any other  corporate  act or  proceeding,  whether of a
similar character or otherwise.

10. Compliance with Securities Laws.

     (a)  Until  such  time  as the  Optioned  Shares  shall  have  been  either
registered under the Securities Act of 1933, as amended (the "Securities  Act"),
or sold pursuant to an exemption  from  registration,  the Company shall utilize
its best efforts to comply with the  reporting  requirements  of Sections 13 and
15(d)  of the  Securities  Exchange  Act of 1934  (whether  or not it  shall  be
required to do so pursuant to such  sections)  and will use its best  efforts to
comply  with  all  other  public  information  reporting   requirements  of  the
Securities and Exchange  Commission (the "SEC") (including,  without limitation,
Rule 144  promulgated by the SEC under the Securities  Act) from time to time in
effect and relating

                                       -8-
<PAGE>

to the availability of an exemption from  registration  under the Securities Act
for the sale of restricted securities.  The Company also will cooperate with the
Optionee in supplying  such  information as may be necessary for the Optionee to
complete  and  file any  information  reporting  forms  presently  or  hereafter
required by the SEC as a condition to the availability of such an exemption.

     (b) Unless  prior to the  issuance  thereof the  Optioned  Shares  shall be
registered  under the  Securities  Act,  as a condition  precedent  to the valid
exercise of an Option the  Optionee  shall  represent  in writing to the Company
that he is acquiring  such Shares for his own account as an  investment  and not
with a view to, or for sale in connection with, the distribution of any thereof.
If the Optioned  Shares shall not be registered  under the  Securities Act at or
prior to the issuance  thereof,  each certificate  representing  Optioned Shares
shall bear a legend customary for securities not registered under the Securities
Act.

     (c) The Company will use its best efforts to qualify,  file or register the
Optioned  Shares in accordance  with the  securities  laws of such states of the
United States of America as may be reasonably  designated by the Optionee and to
obtain  the  consent,  authorization  or  approval  of any  governmental  agency
required in connection with the issuance of such Shares or which may be required
in order that the Optionee may otherwise publicly sell such Shares.

11. Notices.  All notices  required or desired to be given hereunder shall be in
writing and shall be deemed properly given to a party if personally delivered or
mailed by certified mail, return receipt requested, to such party at the address
set forth at the

                                       -9-
<PAGE>

head of this  Agreement or to such other address as shall be specified by notice
duly given. Notices given by certified mail shall be deemed given three business
days after the date of mailing,  and notices delivered in person shall be deemed
given on the date of delivery.

12. Entire  Agreement;  Breach and Waiver.  The provisions hereof constitute the
entire  agreement  between the parties with respect to the subject matter hereof
and supersede any prior written or oral understanding. This Agreement may not be
amended or modified in any manner,  except by an instrument in writing signed by
both parties  hereto.  The failure of either party hereto to enforce at any time
any of the provisions  hereof shall in no way be construed to be a waiver of any
such provision or any other provision,  or of the right of such party thereafter
to enforce each and every such  provision  or other  provision in the event of a
subsequent breach. Any waiver must be in writing and duly authorized.

13. Agreement Binding Upon Successors. This Agreement shall inure to the benefit
of, and shall be binding upon the Company,  its successors and assigns, and upon
the Optionee, his successors and assigns, heirs,  executors,  administrators and
legal representatives.

                                      -10-
<PAGE>

14. Counterparts.  This Agreement may be executed in several counterparts,  each
of which shall be deemed an original, but all of which together shall constitute
one and the same instrument.

15.  Construction.  This  Agreement  shall be  governed  by,  and  construed  in
accordance with, the local laws of the State of New York.

16.  Headings.  The headings  herein are solely for the convenience of reference
and shall be given no effect in the  construction or  interpretation  hereof and
shall not constitute, or be deemed to constitute, a part hereof.

     IN WITNESS  WHEREOF,  the  Company  and the  Optionee  have  executed  this
Agreement as of the day and year first above written.

                                          SELECT THERAPEUTICS INC.

                                          By:
                                              ----------------------------------
                                              Robert Bender, Chairman

                                          Optionee:

                                          --------------------------------------
                                          Dawn van Zant

                                      -11-
<PAGE>

                                    EXHIBIT A

                                                     Date: ______________, 200_

Select Therapeutics Inc.
124 Mount Auburn Street
Suite 200 North
Cambridge, Massachusetts 02138

Attn: Chairman

          Re:  Exercise of Stock Option

Gentlemen:

     Please be advised  that I wish to  exercise my Stock  Option by  purchasing
_________  shares of Common Stock of the Company at the option price of US $ per
share. I enclose herewith a check in the amount of US  $_______________  in full
payment for said shares.

     Please deliver the certificate(s) to me at the following address:

                                                     Sincerely,

                                                     Name:
                                                          ----------------------

                                                     Address:
                                                             -------------------

                                                     ---------------------------

                                                     ---------------------------

                                                     Social Security Number:

                                                     ---------------------------

Enclosure

                                      -12-

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