Document:

Exhibit
10.1

  

THIS
ASSIGNMENT AND CONSENT AGREEMENT (this “Agreement”), made as of the 6th day of June, 2017, between 275
MADISON AVENUE RPW 1 LLC and 275 MADISON AVENUE RPW 2 LLC, having an office in care of RPW Group, Inc., 800 Westchester Avenue,
Rye Brook, New York 10573, hereinafter referred to collectively as the “Owner,” RELMADA THREAPEUTICS, INC.,
having an office at 275 Madison Avenue, Suite 702, New York, New York 10016, hereinafter referred to as the “Assignor,”
and ACTINIUM PHARMACEUTICALS, INC., having an office at 275 Madison Avenue, Suite 702, New York, New York 10016, hereinafter
referred to as the “Assignee.”

 

W
I T N E S S E T H:

 

WHEREAS,
Owner, is the fee simple owner of the building commonly known as and located at 275 Madison Avenue, Suite 702, New York, New York
10016 (the “Building”);

 

WHEREAS,
Owner’s predecessor in interest entered into that certain Agreement of Lease with Assignor dated as of June 9, 2015, as
amended by Commencement Date Agreement and First Amendment of Lease dated as of September 25, 2015, (hereinafter referred to collectively
as the “Lease”) for certain premises located on the seventh (7th) floor of the Building, commonly
known as Suite 702, as more particularly described in the Lease (hereinafter referred to collectively as the “Premises”);

 

WHEREAS,
Assignee has occupied the Premises as licensee of Assignor, and Assignor and Assignee have now agreed that Assignor shall assign
the Lease to Assignee, and Assignee has agreed to assume all of all Assignor’s rights and obligations under the Lease;

 

WHEREAS,
Owner has agreed to consent to the assignment of the Lease by Assignor to Assignee as hereinafter specifically provided;

 

WHEREAS,
capitalized terms not otherwise defined in this Agreement shall have the meanings ascribed to them under the Lease;

 

NOW,
THEREFORE, for and in consideration of the foregoing and for other good and valuable consideration and of the mutual agreements
hereinafter set forth, Owner, Assignor and Assignee stipulate, covenant and agree as follows:

 

ARTICLE
1 - ASSIGNMENT AND ASSUMPTION OF THE LEASE

 

SECTION
1.01. Assignor hereby transfers to Assignee, all of Assignor's right, title and interest in and to the Lease, provided, however,
that Assignee does hereby agree to assume all of the duties, liabilities and obligations of the tenant under the Lease accruing
from and after (but not prior to) the date hereof, including, but not limited to the payment of rent; and covenants and agrees
to save, defend, indemnify and hold Assignor, its members, managers, shareholders, directors, officers, employees, agents successors
and assigns (collectively, “Assignor Indemnitees”) harmless from and against any and all demands, claims, causes of
action, actions, liabilities, obligations, losses, damages, costs, charges, counsel fees and other expenses of every nature and
character whatsoever which may be incurred by Assignor and/or any other Assignor Indemnitees by reason of Assignee's failure to
comply or perform any covenant, term, condition, or agreement in the Lease to be complied with or performed by the tenant thereunder
from and after the date hereof.

 

    	 	Page 1 of 4	 

     

    

 

SECTION
1.02. Assignor covenants and agrees to save, defend, indemnify and hold Assignee, its members, managers, shareholders, directors,
officers, employees, agents successors and assigns (collectively, “Assignee Indemnitees”) harmless from and against
any and all demands, claims, causes of action, actions, liabilities, obligations, losses, damages, costs, charges, counsel fees
and other expenses of every nature and character whatsoever which may be incurred by Assignee and/or any other Assignee Indemnitees
by reason of Assignor's failure to comply or perform any covenant, term, condition, or agreement in the Lease to be complied with
or performed by the tenant under the Lease prior to the date hereof.

 

ARTICLE
2 - CONSENT

 

SECTION
2.01. Owner hereby consents to the assignment of the Lease by Assignor to Assignee, provided, however, that nothing contained
herein shall be construed to: (i) waive, modify, impair or affect any of the provisions of the Lease; (ii) waive payment of the
Rent Arrears; (iii) waive any present or future breach of, or default under, the Lease, or the rights of Owner against any person,
firm, association or corporation liable or responsible for the performance thereof; (iv) enlarge or increase Owner's obligations
or the tenants rights under the Lease, or otherwise; (v) to release Assignor and Assignee from any and all of their respective
liability under the Lease; and (vi) all of the provisions of the Lease are hereby declared to be in full force and effect.

 

SECTION
2.02. This consent is not, and shall not be construed as, a consent by Owner to, or as permitting, any other or further assignments.

 

SECTION
2.03. In the event of any breach of, or default under, the Lease, or the rights of Owner against any person, firm association
or corporation liable or responsible for the performance under the Lease, or in the event of an inconsistency between the provisions
of the Lease and/or this Assignment, the provisions of the Lease shall control and prevail.

 

ARTICLE
3 - REPRESENTATIONS

 

SECTION
3.01. Assignor, for itself and its legal representatives, successors and assigns, covenants and represents to Assignee and Owner
as follows: (i) Assignor has full right, authority and power to assign the Lease to Assignee; (ii) Assignor has not assigned,
transferred, pledged or otherwise encumbered all or any part of its right, title and interest in and to the Lease and/or the Premises,
and the Lease is free and clear of any liens and encumbrances made by Assignor; (iii) except as otherwise specifically provided
for in this Agreement, to Assignor’s knowledge, Assignor is not on the date hereof in default under any of the terms of
the Lease, having performed all of the obligations imposed upon Assignor thereunder, and as of the date hereof, the Lease is in
full force and effect and enforceable in accordance with its respective terms; (iv) except as otherwise specifically provided
for in this Agreement, Assignor has no knowledge of any default in the performance and observance of any obligations contained
in the Lease, to be kept, observed and performed by Owner, or any condition, which with the giving of notice or passage of time,
or both, would constitute a default under the Lease; (v) that it is a corporation duly organized and in good standing; (vi) that
it has all requisite authority to execute and to enter into this Agreement and that the execution of this Agreement will not constitute
a violation of any law, agreement or other rule of governance; and (vii) that the individual executing this Agreement on behalf
of Assignor is so authorized.

 

SECTION
3.02.A. Assignee, for itself and its legal representatives, successors and assigns, covenants and represents to Assignor and Owner
as follows: (i) that it has all requisite authority to execute and to enter into this Agreement and that the execution of this
Agreement will not constitute a violation of any internal by-law, agreement or other rule of governance, (ii) that the individual
executing this Agreement on behalf of Assignee is so authorized; (iii) that the Premises shall continue to be used for the use
permitted under the Lease; and (iv) Assignee has assumed all of the obligations of Assignor under the Lease.

 

    	 	Page 2 of 4	 

     

    

 

B.
Assignee represents and warrants that Assignee is not now acting and shall not in the future act, directly or indirectly, for
or on behalf of any person, group, entity or nation named by any Executive Order or the United States Department of the Treasury
as a terrorist, “Specially Designated and Blocked Persons”, or other banned or blocked person, group, entity,
nation or transaction pursuant to any law, order, rule or regulation that is enforced or administered by the Office of Foreign
Asset Control (“OFAC”) of the United States Department of the Treasury. Assignee further represents and warrants
that Assignee is not now engaged and shall not in the future be engaged, directly or indirectly, in any dealings or transactions
or otherwise be associated with such person, group, entity or nation; and Assignee hereby agrees to defend, indemnify and hold
Owner harmless from and against any and all claims, losses, costs, expenses, damages and liabilities (including, without limitation,
attorneys’ fees) arising from or related to any breach of the foregoing representations.

 

ARTICLE
4 – SECURITY DEPOSIT

 

SECTION
4.01. Assignee acknowledges and agrees regarding the Security Deposit as follows: (i) Assignee shall furnish Owner with cash or
a letter of credit in the amount of Three Hundred Ninety Thousand, Eight Hundred Twenty-Five ($390,825.00) in accordance
with Article 27 of the Lease, and (ii) Section 27D of Article 27 of the Lease regarding the reduction of the Security Deposit
is hereby deleted in its entirety.

 

ARTICLE
5 - MISCELLANEOUS

 

SECTION
5.01. Assignor agrees to reimburse Owner for its legal costs and expenses in connection with preparing this Agreement in the amount
of One Thousand, Two Hundred Fifty and 00/100 ($1,250.00) Dollars. Such payment shall be made directly to Owner’s
attorney simultaneously with the execution and delivery of this Agreement.

 

SECTION
5.02. All other terms, covenants and conditions of the Lease and all exhibits and schedules thereto shall remain in full force
and effect, are hereby ratified, confirmed and incorporated herein by reference as though set forth fully herein at length.

 

SECTION
5.03. This Agreement may be executed in counterparts, which when taken together shall be construed as a complete agreement.

 

[Signature
page(s) follow]

 

    	 	Page 3 of 4	 

     

    

 

IN
WITNESS WHEREOF, duly authorized representatives of the parties hereto have executed this Agreement as of the day and year
first above written.

 

	 	275
    MADISON AVENUE RPW 1 LLC, (Owner)
	 	 	 
	 	By:	/s/
    Robert P. Weisz
	 	Name:	Robert
    P. Weisz
	 	Title:	President
	 	 	 
	 	275
    MADISON AVENUE RPW 2 LLC, (Owner)
	 	 	 
	 	By:	/s/
    Robert P. Weisz
	 	Name:	Robert
    P. Weisz
	 	Title:	President
	 	 	 
	 	RELMADA
    THERAPEUTICS, INC., (Assignor)
	 	 	 
	 	By:	/s/
Sergio Traversa
	 	Name:	Sergio
    Traversa
	 	Title:	CEO
	 	 	 
	 	ACTINIUM
    PHARMACEUTICALS, INC., (Assignee)
	 	 	 
	 	By:	/s/
    Steve O’Loughlin
	 	Name:	Steve
    O’Loughlin
	 	Title:	Principal
    Financial Officer

 

 

Page 4 of 4Exhibit
10.3

 

AMENDED
AND RESTATED LICENSE AGREEMENT

 

This
Amended and Restated License Agreement (this “Agreement”) is entered on this 8th day of June, 2017, between Relmada
Therapeutics, Inc., a Nevada corporation (“Relmada”), and Actinium Pharmaceuticals, Inc., a Delaware corporation (“Actinium”),
with respect to the office space (the “Premises”) located on the 7th floor of the office building located
at 275 Madison Avenue, New York, New York (“the Building”), upon and subject to the following terms and conditions:

 

This
Agreement amends and restates in its entirety that certain Office Space License Agreement, dated as of March 10, 2016 and effective
as of January 1, 2016, between Relmada and Actinium (the “Original Agreement”) for office space within the Premises.
This Agreement is intended to and does completely amend and restate the Original Agreement.

 

A.       As
of the date hereof, Relmada and Actinium have entered into an Assignment and Assumption Agreement (the “Assignment and Assumption”)
pursuant to which Actinium will occupy the entire Premises in accordance with the terms thereof and assume Relmada’s obligations
under that certain Lease, dated June 9, 2015, (the “Lease”) between 275 Madison Avenue RPW 1 LLC and 275 Madison Avenue
RPW 2 LLC RPW (as successor in interest to GP 275 Owner, LLC) and Relmada, among other things.

 

B.       Relmada
and Actinium desire to amend and restate the Original Agreement with respect to Actinium’s occupancy of the Client Area
(as defined under the Original Agreement”), to reflect Actinium’s continued license to use the furniture, fixtures,
equipment and tenant improvements (collectively, “FFE”) located in the Premises.

 

NOW
THEREFORE, in consideration of the License Fee (as hereinafter defined) to be paid, the mutual covenants and agreements herein
contained, and other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the parties
agree as follows:

 

1.       License
to Use: (a) Relmada hereby grants Actinium the license to use the FFE that is located in the Premises, a schedule of which is
attached hereto as Exhibit A, for a period of time that shall be coterminous with the Lease (the “Term”). For the
duration of the Term, Actinium shall pay Relmada the amount of $7,529.00 per month (the “Licensee Fee”) on the first
calendar day of each month.

 

(b)
This FFE use license is granted, and Actinium hereby accepts such license, on an “AS-IS, WITH ALL FAULTS” basis, without
recourse, representation or warranty of any kind or nature, express or implied, including without limitation, habitability, merchantability
or fitness for a particular purpose.

 

(c)
During the Term, Actinium, at its sole cost and expense, shall keep and maintain the FFE, in a good state of repair, normal wear
and tear excepted, and shall be responsible for replacement and/or repair of any FFE which is not returned because it is damaged,
lost or stolen. Actinium shall not remove any of the FFE from the Premises without prior written approval of Relmada. Relmada
shall be granted access to the Premises at reasonable times, upon advance written notice for the purposes of inspecting the FFE.
Relmada shall have no obligation to repair, maintain or insure any of the FFE. Actinium, at its sole cost and expense, shall insure
the FFE (and name Relmada as additional insured) for its full replacement value.

 

     

     

    

 

(d)
At the expiration or earlier termination of Term, the FFE shall be returned and surrendered to Relmada, at such location as designated
by Relmada, in good condition and repair, reasonable wear and tear excepted.

 

(e)
Actinium shall not have the right to and shall not (i) remove the FFE from the Premises or modify the FFE in any way, or
(ii) pledge or encumber any of the FFE in any way.

 

2.       Right
to Purchase: Actinium shall have at any time during the Term of this Agreement the right to purchase the FFE by delivering written
notice of such intent to Relmada together with a tender of payment of a purchase price equal to the FFE Consideration (as hereinafter
defined). The purchase contemplated by the previous sentence will be effected by the execution and delivery by the parties of
a Bill of Sale in form and substance mutually acceptable to both parties. “FFE Consideration” shall mean $ 496,909.00
less any License Fee(s) previously paid by Actinium.

 

3.       Termination
of License to use “Client Area” (as defined in the Original Agreement): Upon the execution by both parties of the
Assignment and Assumption, the Original Agreement shall be deemed terminated as relating to Actinium’s occupancy of the
Client Area, except for any covenant, term, condition or agreement to be complied with or performed by Actinium under the Original
Agreement prior to the date hereof, which shall be deemed to survive.

 

4.
      Default: Each of the following shall constitute a “Default” by Actinium:

 

(a)       The
failure of Actinium to pay any sum when due, and such failure continues for a period of five (5) days thereafter.

 

(b)       Actinium
shall become insolvent or unable to pay its debts as they become due, or Actinium notifies Relmada that it anticipates either
condition; or Actinium files a petition under any section or chapter of the United States Bankruptcy Code, as amended from time
to time; or a petition shall be filed against Actinium under such statute or Actinium notifies Relmada that it knows such a petition
will be filed and such petition is not withdrawn or dismissed within sixty (60) days of filing; or a receiver or trustee is appointed
to take possession of substantially all of Actinium’s assets located at the Premises or of Actinium’s interest in
this Agreement is legally attached or seized.

 

(c)       Actinium
shall fail to perform, in whole or in part, any of the other obligations under this Agreement and such failure or non-performance
continues for a period of five (5) days after written notice thereof has been given by Relmada.

 

5.       Remedies
- Termination: (a) If a Default occurs, then at any time thereafter, prior to the curing thereof, Actinium shall be deemed to
have automatically exercised its right to purchase the FFE pursuant to Section 2 hereof and the FFE Consideration shall be immediately
due and payable, and Relmada may exercise any and all rights and remedies available to Relmada, with or without notice of demand,
under this Agreement, at law, or in equity, to recover and collect the FFE Consideration and/or to terminate this Agreement.

 

(b)
Actinium shall pay all reasonable attorney and other fees, expenses and costs incurred by Relmada in protecting its rights under
this Agreement and/or for any action taken by Relmada to collect any amounts due by Actinium under this Agreement.

 

    	 	2	 

     

    

 

6.       Indemnification:
Actinium covenants and agrees to indemnify and hold Relmada harmless from and against any and all losses, damages, costs, charges,
counsel fees and other expenses of every nature and character whatsoever which may be incurred by Relmada by reason of Actinium's
use of the FFE and by reason of Actinium’s failure to comply or perform any covenant, term, condition, or agreement in this
Agreement to be complied with or performed by Actinium.

 

7.       Entire
Agreement: This Agreement, including all Exhibit(s) attached hereto (which Exhibit(s) are hereby incorporated herein and shall
constitute a portion hereof), contains the entire agreement between Relmada and Actinium with respect to the subject matter hereof.

 

8.       Severability:
It is the intention of the parties hereto that if any provision of this Agreement is capable of two constructions, one of which
would render the provision invalid and the other of which would render the provision valid, then the provision shall have the
meaning which renders it valid. If any term or provision of this Agreement, or the application thereof to any person or circumstance,
shall to any extent be invalid or unenforceable, the remainder of this Agreement, or the application of such term or provision
to other persons or circumstances, shall not be affected thereby, and each term and provision of this Agreement shall be valid
and enforced to the fullest extent permitted by law.

 

9.       Counterparts:
This Agreement may be executed in any number of separate counterparts, all of which counterparts taken together shall constitute
the entirety of this Agreement.

 

IN
WITNESS WHEREOF, Relmada and Actinium have executed this Agreement as of the date first above written.

 

	RELMADA
    THERAPEUTICS, INC.	 
	 	 	 
	By:	/s/
    Sergio Traversa	 
	Name:	Sergio
    Traversa	 
	Title:	Chief
    Executive Officer	 

 

	ACTINIUM
    THERAPEUTICS, INC.	 
	 	 	 
	By:	/s/
    Steve O’Loughlin	 
	Name:	Steve
    O’Loughlin	 
	Title:	Principal
    financial Officer	 

 

    	 	3	 

     

    

 

EXHIBIT
A

 

ITEMIZED
INVENTORY OF FFE

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