Document:

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                                                                    EXHIBIT 10.1

                            TKT Management Bonus Plan
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PURPOSE

The purpose of the TKT Retention Management Bonus Plan (the "Plan") is to;

      -     Enable Transkaryotic Therapies, Inc. ("TKT" or the "Company") to
            retain certain management employees from year to year and to provide
            such employees with incentive to remain with TKT after the
            conclusion of any given calendar year.

      -     Provide participating management employees with motivation and
            incentive to help drive TKT's and the individual's near and long
            term success.

      -     Align compensation with Company goals and the interests of the
            shareholders.

      -     Base variable compensation on individual and team performance.

PLAN DESIGN

Rewards under the Plan may consist of cash, stock options or a combination of
both. The cash component is designed to provide near-term reward based on annual
performance against goals and foster continued retention. The stock component
encourages continued retention and longer- term achievement (through options and
vesting periods). Award amounts will be determined by TKT with consideration for
industry practices, internal equity and company resources.

Notwithstanding anything in this document to the contrary, the fully funded
bonus(es) provided pursuant to this Plan will be based on a pool of management
bonus funds. The Company's ability to meet, exceed or fall short of financial
targets established in the sole discretion of the Company will determine the
management bonus fund pool available for distribution.

PLAN DETAILS

Bonuses will be targeted as a percentage of annual base salary and Base Shares
Options for each Plan participant. "Base Share Options" shall be determined by
TKT in its sole discretion. Plan participants will be provided with this
information or may contact the Human Resources Department with questions
regarding their applicable Base Salary percentage or Base Share Options.

Actual bonus amounts will be determined in the Company's sole discretion and
will be calculated based on the achievement of Company Goals and Individual
Goals, as such terms are defined herein. Generally, if a bonus is awarded, half
of such bonus, if any, will be determined based upon the achievement of Company
Goals and the balance will be based upon the achievement of Individual Goals.

"Company Goals" shall include those goals set forth for the Company as a whole
at the beginning of or during a given Plan Year as set forth on the TKT
Management Bonus Plan Schedule to be entered into between the Company and each
participant (the "Bonus Plan Schedule"). "Individual Goals" shall include goals
provided by an employee's

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supervisor to an employee at the beginning of or during a given Plan Year as set
forth on the Bonus Plan Schedule.

The Company retains the right to weight each of the goals as it deems
appropriate and, thereby, determine what bonus, if any, is earned by each
participant in this Plan.

Participants who may be eligible for a bonus pursuant to this Plan shall be
provided with information regarding their position classification. TKT reserves
the right to determine the actual bonus to be provided, if any, to each
participating employee.

      CASH TARGET BONUS

After meeting all eligibility requirements and after achieving all Company and
Individual Goals established by the Company in its sole discretion, each
participating employee will be eligible for a cash target bonus, calculated as a
percentage of his/her base salary.

      STOCK OPTION TARGET

After meeting all eligibility requirements and after achieving all Company and
Individual Goals established by the Company in its sole discretion, each
participating employee will be eligible for a stock option target bonus.

TKT reserves the right to grant additional stock options and pay additional cash
bonuses in excess of the targets or to grant stock options or pay cash bonuses
that are below the targets whether or not the targets are achieved, subject in
all cases to the approval of TKT's Board of Directors.

Stock options granted pursuant to this Plan shall be granted with an exercise
price equal to the fair market value on the date of any such grant. In addition,
stock options shall be granted with a three year vesting schedule. All stock
options granted under this Plan are subject to TKT Board of Directors approval.
The stock options shall also be subject to any option agreement(s) and/or
plan(s) which are in effect from time to time.

SUMMARY OF PROGRAM DETAILS

      PLAN YEAR

January 1 through December 31 annually

      BONUS POOL DOLLARS

The plan funding is subject to change based upon whether TKT achieves the
minimal financial threshold determined by the Company in its sole discretion.
The extent to which the Company does or does not meet such minimum financial
performance goals may vary TKT's contributions to the Plan and thus the total
bonus dollars available in the pool for distribution. The actual amount
contributed to the Plan, if any, shall be determined by TKT in its sole
discretion.

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      BONUS PAYMENT

If a cash bonus is to be paid out under the Plan, such bonus will be paid to
only those employees remaining employed by the Company on the date of such
payment. It is anticipated that the TAG evaluation of Individual and Company
Goals will be made by the end of January of the year following the Plan Year. It
is also anticipated that the participant pay out will be on the later of two
days after the TKT annual earning release or February 15th of the year following
the Plan Year which is consistent with TAG.

      ELIGIBILITY

Certain management-level employees of TKT will be eligible pursuant to this
Plan. Employees are only eligible if they enter into a Bonus Plan Schedule with
the Company.

Participants will only be eligible for bonus payments hereunder if they are in
good standing with the Company. Employees who have been placed on a performance
improvement plan may not be eligible under this Plan. Employees are eligible for
a bonus under this Plan only if they are employed by TKT on the date the bonus
payments are distributed.

Participants must be employed in or promoted into a management bonus plan
classification before September 1 of the Plan Year. Plan participants who join
TKT or are promoted into a management bonus plan classification before September
1 of the Plan Year and after March 1 of the Plan Year will be eligible to
receive a pro rata bonus based on the time between their start date and December
31 of the Plan Year..

Plan participants who are promoted during the Plan Year will not see an effect
on the cash or stock option target bonuses for the current Plan Year.

Eligible part time employees will receive pro rated bonuses based on their
number of regularly scheduled work hours.

Employees who are eligible to receive incentive bonus(es) through an individual
or group plan of TKT (including sales incentive plans and individual employment
agreements) other than this Plan, will generally be ineligible under this Plan.

      HOW CASH BONUS PAY AFFECTS YOUR BENEFITS

The bonus amount, if any, will be taken into account when calculating
participation in the 401k plan. The elected contribution percentage will be
deducted from the lump sum bonus payment.

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OTHER PROVISIONS

Earnings from this Plan will be subject to applicable taxes and withholdings.

Subject to applicable law, TKT expressly reserves the right to deduct any
amounts or monies owed or due by a participating employee to TKT, for any
reason, from the payments provided hereunder. By signing below, the employee
specifically permits such a deduction.

This Plan does not constitute a contract of employment or guarantee a bonus
award payment. Except as may be amended by a written agreement signed by the
President and CEO of TKT, each employee remains employed at-will and either the
employee or the Company may terminate the employment relationship at any time.
The Company does reserve the right to review, alter, amend or terminate this
Plan at anytime. The Company also retains the right to interpret the Plan in its
sole discretion. This Plan and each employee's eligibility hereunder may be
reviewed by the Company on an annual basis.

_______________________________           ______________________________
Employee Name                             Plan Year

_______________________________           ______________________________
Employee Signature                        Date

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                     2005 TKT MANAGEMENT BONUS PLAN SCHEDULE

This TKT Management Bonus Schedule is entered into between the Company and the
employee listed below in accordance with the TKT Management Bonus Plan (the
"Plan") and in all respects is subject to the terms of the Plan, a copy of which
has been furnished to the Employee with this Schedule.

BONUSABLE TKT COMPANY GOALS                                                  50%

REPLAGAL                              I2S

GA-GCB                                DYNEPO

PORTFOLIO / RESEARCH                  CORPORATE GOALS

BUSINESS DEVELOPMENT

BONUSABLE INDIVIDUAL GOALS                                                   50%

List 3-5 goals the individual will be evaluated against at the end of the plan
year.

1.                                                                        _____%

2.                                                                        _____%

3.                                                                        _____%

4.                                                                        _____%

5.                                                                        _____%

Name:__________________________________        Cash Target Bonus:_______________

Title:_________________________________        Stock Option Target: ____________

********************************************************************************
Employee signature:________________________    Date:____________________________

Supervisor's signature:____________________    Date:____________________________

                                       6<PAGE>

                                                                   EXHIBIT 10.01

                        SHARE SALE AND PURCHASE AGREEMENT

                                     Between

                  Perbio Science International Netherlands B.V.

                                       and

                                 Cidron Group AB

                                    regarding

               the sale and purchase of all outstanding shares in

                             Atos Medical Holding AB

                         Advokatfirman Hammarskiold & Co
                                  Skeppsbron 42
                                   PO Box 2278
                               SE-103 17 Stockholm

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                                TABLE OF CONTENTS

<TABLE>
<CAPTION>
CLAUSE                                                                                          PAGE
<S>                                                                                             <C>
1.     DEFINITIONS AND INTERPRETATIONS......................................................      4
2.     SALE AND PURCHASE....................................................................      8
3.     PURCHASE PRICE.......................................................................      8
4.     CONDITIONS PRECEDENT.................................................................     11
5.     COVENANTS............................................................................     12
6.     COMPLETION...........................................................................     14
7.     REPRESENTATIONS AND WARRANTIES OF THE VENDOR.........................................     16
8.     REPRESENTATIONS AND WARRANTIES OF THE PURCHASER......................................     21
9.     REMEDIES.............................................................................     21
10.    INTERIM MEASURES.....................................................................     22
11.    COSTS AND EXPENSES...................................................................     23
12.    CONFIDENTIALITY......................................................................     23
13.    ANNOUNCEMENTS........................................................................     24
14.    ASSIGNMENTS..........................................................................     24
15.    ENTIRE AGREEMENT AND AMENDMENTS......................................................     24
16.    NOTICES..............................................................................     24
17.    INVALIDITY...........................................................................     25
18.    WAIVER...............................................................................     26
19.    GOVERNING LAW AND DISPUTES...........................................................     26
</TABLE>

LIST OF EXHIBITS

EXHIBIT           DESCRIPTION

Exhibit 1.1 (a)   "Benchmark Net Working Capital" calculation
Exhibit 1.1 (b)   "Net Working Capital calculation"
Exhibit 1.1 (c)   "Subsidiaries"
Exhibit 5.1(a)    Planned actions outside ordinary course
Exhibit 6.2(v)    List of Vendor appointed Directors
Exhibit 7.1.1     Share Capital of the Group
Exhibit 7.5 (i)   Agreements outside ordinary course
Exhibit 7.10.1    The Intellectual Property Rights
Exhibit 7.10.3    Current infringements of the Intellectual Property Rights
Exhibit 7.11      Material Contracts
Exhibit 7.14.3    Transaction Bonuses.

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                                                                               3

                        SHARE SALE AND PURCHASE AGREEMENT

This Share Sale and Purchase Agreement is made on the 7th day of March 2005 by
and between on the one hand;

Perbio Science International Netherlands B.V., a company incorporated under the
laws of the Netherlands and whose registered office is at Drentestraat 24, BG,
1083 HK Amsterdam, the Netherlands

(hereinafter referred to as the "Vendor"), and on the other hand;

Cidron Group AB, org. no. 556669-5820, a company incorporated under the laws of
Sweden and whose registered office is at Stureplan 4A, 114 35 Stockholm, Sweden
(hereinafter referred to as the "Purchaser").

WHEREAS;

A.    The Vendor is the owner of 1,000 shares (hereinafter referred to as the
      "Shares") representing 100% of the capital and votes in Atos Medical
      Holding AB; (hereinafter referred to as the "Company").

B.    The Company is part of the Fisher Scientific International Inc. Group and
      the Vendor is the parent company of the Swedish Medical Device business
      within the Fisher Scientific International Inc. Group.

C.    The Purchaser is a special purpose entity indirectly owned by Nordic
      Capital V Ltd.

D.    The Purchaser desires to purchase and the Vendor wishes to sell the
      Shares.

E.    Representatives of Seller and Purchaser have specifically agreed that such
      sale and purchase shall be made with only a limited number of basic
      representations and warranties made by the Vendor that survive completion
      of the sale and purchase of the Shares.

NOW THEREFORE THE PARTIES HEREBY AGREE as follows:

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                                                                               4

1.    DEFINITIONS AND INTERPRETATIONS

1.1   In this Agreement and in the Exhibits hereto, which shall form part of
      this Agreement, the following words and expressions shall have the
      meanings respectively set out opposite them;

"Accounting Principles" shall mean the US GAAP accounting principles that have
                        been consistently applied by the Group since September
                        2003 for purposes of the preparation of the Fisher
                        internal monthly GMM reports;

"Agreement"             shall mean this Share Sale and Purchase Agreement and
                        all the schedules and exhibits attached hereto, each of
                        which constitutes an integral part of this Agreement;

"Benchmark Net
Cash/Debt"              shall mean the estimated Net Cash/Debt as of Completion,
                        which shall be USD nil (0.00);

"Benchmark Net
Working Capital"        shall mean the average level of Net Working Capital for
                        the Group during 2004. The Benchmark Net Working Capital
                        shall thus be SEK 27.5 million, as calculated in
                        accordance with Exhibit 1.1 (a);

"Business Day"          Any day (other than a Saturday or Sunday) on which banks
                        in Stockholm are open for a full range of banking
                        transactions;

"Company"               shall have the meaning set out in the introductory
                        paragraph (A) above;

"Company's Auditors"    shall mean the auditing firm Deloitte & Touche with Elna
                        Lembrer Astrom as main responsible auditor;

"Completion"            shall mean the completion of this Agreement in
                        accordance with Section 6 below;

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                                                                               5

"Completion Auditor"    shall have the meaning set out in Section 3.3(b) below;

"Completion Date"       shall mean the date on which Completion occurs or is
                        deemed to have occurred in accordance with this
                        Agreement as set forth in Section 6.1 below;

"Completion Net
Cash/Debt"              shall have the meaning set out in Section 3.3 below;

"Completion Net
Working Capital"        shall have the meaning set out in Section 3.3 below;

"Completion Payment"    shall have the meaning set out in Section 3.1 below;

"Completion Statement"  shall have the meaning set out in Section 3.3 below;

"Conditions Precedent"  shall mean the conditions set out in Section 4.1 below;

"Final Purchase Price"  shall mean the final purchase price for the Shares as
                        established in accordance with Section 3.3 below;

"Group"                 shall mean the Company and the Subsidiaries jointly;

"Group Companies"       shall mean the Company and the Subsidiaries;

"Intellectual Property
Rights"                 shall mean the registered patents, the registered and
                        unregistered trademarks, copyrights, designs, trade and
                        business names, including applications for any of these
                        rights as listed in Exhibit 7.10.1;

"Key Employees"         shall mean Tommy Hedberg, Tommy Niklasson, Jan-Ove
                        Persson and Claes Hansson;

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                                                                               6

"Material Contracts"    shall mean each of the contracts which have a
                        material effect on the results and financial condition
                        of the Group Companies, as set out in Exhibit 7.11;

"Net Cash/Debt"         shall mean (i) cash and marketable cash instruments with
                        maturity not more than 12 months minus (ii) long term
                        interest bearing liabilities, short term interest
                        bearing liabilities, accrued unpaid income taxes (net of
                        any income tax receivable) related to the income tax
                        year ending December 31 2004, minority interest
                        liability, declared unpaid dividends and decided unpaid
                        group contributions, as determined in accordance with
                        the Accounting Principles;

"Net Working Capital"   shall mean the difference between current assets and
                        current liabilities to be calculated based on the line
                        items set out in Exhibit 1.1(b), as determined in
                        accordance with the Accounting Principles;

"Party"                 shall mean any of Vendor or the Purchaser;

"Parties"               shall mean the Vendor and the Purchaser collectively;

"Preliminary Purchase   shall mean the preliminary purchase price set out in
Price"                  Section 3.1 below;

"Purchaser"             shall have the meaning set out in the Preamble to this
                        Agreement;

"Shares"                shall have the meaning set out in the introductory
                        paragraph (A) above;

"Signing Date"          shall mean the date first above written;

"STIBOR"                shall mean the Stockholm Interbank Offered Rate;

"Subsidiaries"          shall mean the entities listed in Exhibit 1.1(c);

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                                                                               7

"USD"                   shall mean the lawful currency of the United States of
                        America;

"Vendor"                shall have the meaning set out in the introductory
                        paragraph above;

"Vendor's Knowledge"    shall mean the actual knowledge of Todd
                        DuChene, Mark Dmytruk and Demaris Mills following their
                        due and careful inquiries with the Key Employees.

1.2   The following provisions shall apply to the construction and
      interpretation of this Agreement and its Exhibits:

      (a)   References to statutes, acts and the like of whatever jurisdiction
            shall include any modification, re-enactment or extension thereof
            whether made before or after the signing of this Agreement and any
            orders, regulations, instruments or other subordinate legislation
            made there under in force from time to time;

      (b)   The masculine gender shall include the feminine and neuter and the
            singular number shall include the plural and vice versa;

      (c)   References to persons shall include corporate bodies, corporate
            entities, firms, unincorporated associations and partnerships;

      (d)   The headings are inserted for convenience only and shall not affect
            the construction of this Agreement;

      (e)   The terms "material" or "material to the Group" and the concept of
            the "material" nature of an effect upon the Group shall be measured
            relative to the entire business of the Company and the Subsidiaries,
            taken as a whole, as such business is currently being conducted;

      (f)   References to Sections, sub-sections and Exhibits are to the
            Sections and sub-sections of and Exhibits to this Agreement and
            include documents, etc. referred to in such Sections, sub-sections
            and Exhibits;

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                                                                               8

2.    SALE AND PURCHASE

2.1   Subject to the terms of this Agreement, the Vendor shall sell and transfer
      the Shares to the Purchaser and the Purchaser shall purchase the Shares
      from the Vendor at Completion.

2.2   The Shares shall be sold free from all liens and encumbrances and together
      with all accrued benefits and rights pertaining thereto.

3.    PURCHASE PRICE

3.1   PURCHASE PRICE; COMPLETION PAYMENT

      The Preliminary Purchase Price shall be (A) USD one hundred and ten
      million (110,000,000) plus (B) the Benchmark Net Cash/Debt (such net
      amount referred to hereinafter as the "Completion Payment"). The
      Completion Payment shall be subject to the Post-Completion Adjustment in
      accordance with Section 3.3 below.

3.2   PAYMENT OF THE COMPLETION PAYMENT

      The Completion Payment shall be paid in full at Completion in immediately
      available funds to the bank account(s) identified by Vendor.

3.3   POST-COMPLETION ADJUSTMENT OF COMPLETION PAYMENT

      Within thirty (30) days after the Completion Date, Vendor shall, with the
      assistance of the Company, prepare and deliver to Purchaser (A) an audited
      determination of the Net Cash/Debt of the Group as of the Completion Date
      without giving regard to any payments made at the Completion, prepared by
      applying the Accounting Principles (the "Completion Net Cash/Debt") and
      (B) an audited determination of the Net Working Capital of the Group as of
      the Completion Date, prepared by applying the Accounting Principles (the
      "Completion Net Working Capital"). The proposed determinations of (A) and
      (B)

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                                                                               9

      hereinafter referred to as the "Completion Statement". The calculation of
      the Completion Net Cash/Debt and the Completion Net Working Capital shall
      be prepared by using currency exchange rates applicable as of the
      Completion Date as quoted by Reuters on page 1 FED Federal Reserve Bank of
      New York currency fixing rates at 10.00 am EST on the Completion Date.

(a)   If Purchaser does not object to such determination by Vendor of the
      Completion Net Cash/Debt and/or the Completion Net Working Capital by
      written notice of objection delivered to Vendor within twenty (20) days
      after Purchaser's receipt of the Completion Statement, the Completion Net
      Cash/Debt and/or the Completion Net Working Capital shall be deemed final
      and binding upon the Parties.

(b)   If Purchaser delivers to Vendor a notice of objection in respect of the
      Completion Statement and the Parties cannot agree upon the determination
      thereof within fifteen (15) days of delivery of such notice of objection,
      then the Purchaser shall within twenty five (25) days of delivery of the
      notice of objection submit its final proposal for the determination of the
      Completion Net Cash/Debt and/or the Completion Net Working Capital to the
      Vendor and to KPMG acting as a completion auditor for the Parties (the
      "Completion Auditor"). If the Purchaser does not submit its final proposal
      for the determination of the Completion Net Cash/Debt and/or the
      Completion Net Working Capital within the specified time period, the
      Completion Statement shall be deemed final and binding upon the Parties.

(c)   Within thirty (30) days of the submission of any dispute concerning the
      determination of the Completion Statement, the Completion Auditor shall
      render its decision determining the Completion Net Cash/Debt and/or the
      Completion Net Working Capital. After the Completion Auditor has rendered
      the decision determining the Completion Net Cash/Debt and/or the
      Completion Net Working Capital, the Completion Statement determined by the
      Completion Auditor shall be final and binding upon the Parties, unless
      either Party within fifteen (15) days from the Completion Auditor's
      decision notifies the other Party in writing of its non-satisfaction with
      the

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                                                                              10

      Completion Statement and within fifteen (15) days from such notice
      initiates arbitration in accordance with Section 19 below.

(d)   The fees and expenses of the Completion Auditor for any determination
      under this Section 3 shall be borne by the Vendor and the Purchaser
      equally.

(e)   Upon the final determination of the Completion Statement, the Parties
      shall make the following adjustments and applicable payments (the
      "Post-Completion Adjustment"):

      (i)   If, pursuant to such final determination, the Completion Net
            Cash/Debt is less than the Benchmark Net Cash/Debt, then the
            Completion Payment shall be decreased by the amount of such
            difference and the Vendor shall reimburse the Purchaser such amount
            in accordance with Section 3.3(f).

      (ii)  If, pursuant to such final determination, the Completion Net
            Cash/Debt is greater than the Benchmark Net Cash/Debt, then the
            Completion Payment shall be increased by the amount of such
            difference and Purchaser shall pay Vendor such amount in accordance
            with Section 3.3(f).

      (iii) If the Completion Net Working Capital is less than SEK 25.5 million,
            the Completion Payment shall be decreased by the amount of such
            difference and the Vendor shall reimburse the Purchaser such amount
            in accordance with Section 3.3(f) below.

      (iv)  If the Completion Net Working Capital is higher than SEK 29.5
            million, the Completion Payment shall be increased by the amount of
            such difference and the Purchaser shall pay the Vendor such amount
            in accordance with Section 3.3(f) below.

(f)   Any Post-Completion Adjustment shall bear interest from the Completion
      Date to the date of payment thereof, at an interest rate equal to four
      percent (4 %) per annum calculated on the basis of actual number of days
      elapsed from the Completion Date and a 360 day year,
<PAGE>

                                                                              11

      and shall be paid within five (5) Business Days after the final
      determination of the Completion Statement under sub-sections (a) through
      (c) above by wire transfer in immediately available funds to the receiving
      Party to the account(s) specified in writing by such Party.

(g)   The Purchaser and the Vendor respectively shall give each and its
      representatives access within normal business hours to the books and
      records of the Group to enable each Party to determine the Completion
      Payment, the Completion Net Cash/Debt and the Completion Net Working
      Capital and to verify, control and investigate any decision rendered by
      the Completion Auditor.

(h)   Payments to the respective parties under this Section 3.3 shall be netted
      out against each other to render a final payment from one of the Parties.

4.    CONDITIONS PRECEDENT

4.1   The obligations of the Parties to complete the sale and purchase of the
      Shares under this Agreement shall be subject to the fulfillment prior to
      or at Completion, unless waived in writing, of each of the following
      conditions precedent (the "Conditions Precedent"):

4.1.1 The obligations of the Vendor and the Purchaser are conditional upon the
      obtaining of clearance or a decision not to take any further action from
      the competition authorities in Germany.

4.1.2 The obligations of the Purchaser are conditional upon that there has not
      occurred any event or circumstance which has a material adverse effect on
      the business, financial condition, assets or prospects of the Group taken
      as a whole.

4.2   Fulfillment of the Conditions Precedent

4.2.1 The Parties undertake to use all reasonable endeavors to procure the
      fulfillment of the Conditions Precedent and otherwise to complete the
      transaction contemplated herein.

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                                                                              12

4.2.2 Should Completion not occur due to the non-fulfillment of the Conditions
      Precedent, none of the Parties shall be under any obligation to compensate
      the other Party for any losses or costs incurred as a result of the
      contemplated transaction.

5.    COVENANTS

5.1   From the Signing Date until Completion, the Vendor shall use its
      reasonable efforts to cause the Group:

      (a)   to operate its business in the ordinary course consistent with past
            practice, except as set out in Exhibit 5.1(a) hereof;

      (b)   to preserve the relationships with suppliers, customers,
            distributors, cooperation partners and others having business
            dealings with a Group Company;

      (c)   to maintain its present insurance coverage;

      (d)   not to dispose of or encumber any of the assets of the Group other
            than in the ordinary course of business;

      (e)   not to authorize, issue or otherwise grant any options, warrants,
            conversion rights or other agreements pursuant to which a Group
            Company may be required to purchase, redeem, issue or sell any
            shares or other securities;

      (f)   to prepare the final consolidated statutory accounts of the Group in
            accordance with Swedish GAAP for the financial year 2004 as soon as
            practicable and take all reasonable measures to facilitate a smooth
            audit of such statutory accounts.

5.2   The Vendor shall, between the Signing Date and the Completion, consult
      with the Purchaser prior to taking any material decisions regarding the
      Group and/or the Group Companies not previously disclosed to the Purchaser
      during the course of the Purchaser's due diligence.

<PAGE>
                                                                              13

5.3   The Vendor shall, between the Signing Date and the Completion, cause the
      Group Companies to afford the Purchaser's employees, consultants, banks
      and advisors reasonable access, at all times during normal business hours,
      reasonable notice having been given, to management personnel and auditors
      of the Group Companies and to the accounts, books and records of the Group
      Companies. Such right of access includes discussions between the Purchaser
      and the management and independent auditors of the Group Companies.

5.4   The Purchaser shall, between the Signing Date and the Completion, use all
      reasonable endeavors to fulfill or procure the fulfillment of the
      condition set out in Section 4.1.1 above and will notify the Vendor in
      writing, immediately after it becomes aware of the satisfaction of such
      conditions. The Vendor shall cooperate with and furnish information as
      requested by the Purchaser in order to facilitate the fulfillment of the
      condition set out in Section 4.1.1.

      In the event the relevant competition or other authorities would not be
      prepared to give its clearance to the sale and purchase contemplated
      herein, the Purchaser undertakes to negotiate in good faith with the
      relevant authorities and, as the case may be, with the Vendor, in order to
      obtain timely clearance and to take any reasonable measures required by
      the authorities in order for the said sale and purchase to not be
      prohibited or restricted in any material way. For the avoidance of doubt,
      the Purchaser's undertaking pursuant to the preceding sentence does not
      include any restructuring of or changes in the business operations of the
      Purchaser, affiliates of the Purchaser, the Company or any of the
      Subsidiaries. Measures taken pursuant to this Section 5.4 shall not
      entitle the Purchaser to any compensation of any kind from the Vendor. The
      Vendor shall be given the opportunity to participate in all negotiations
      with the competition authorities, except for negotiations pertaining to
      the business of the Purchaser and the affiliates of the Purchaser.

<PAGE>
                                                                              14

6.    COMPLETION

6.1   Completion shall take place, unless otherwise agreed in writing between
      the Parties, at the offices of Hammarskiold & Co in Stockholm, Sweden on
      (i) the eighth Business Day following the satisfaction or waiver of the
      Conditions Precedent in Section 4.1.1 with effect as of March 31, 2005,
      provided that such Condition Precedent has been satisfied or waived on or
      prior to March 31, 2005, or (ii) on the last Business Day of a calendar
      month occurring first but not earlier than eight (8) Business Days after
      the date upon which the Condition Precedent in Section 4.1.1 is satisfied
      or waived, if such Conditions Precedent have been satisfied or waived
      after March 31, 2005, (the "Completion Date").

      If Completion has not occurred on or before May 31, 2005, this Agreement
      shall automatically become null and void and neither Party shall have any
      claims against each other by reason thereof.

6.2   At Completion, the Vendor shall:

      (i)   unless Annual General Meetings of each of the Group Companies have
            already been held prior to Completion, hold Annual General Meetings
            of each of the Group Companies;

      (ii)  deliver the share certificates representing the Shares, duly
            endorsed to the Purchaser; free and clear of any and all liens,
            charges and other encumbrances;

      (iii) deliver the original share register (Sw. aktieboken) of the Company;

      (iv)  deliver to the Purchaser the share registers and share certificates,
            if such certificates have been issued, representing all shares
            directly and indirectly held in the Subsidiaries;

      (v)   deliver to the Purchaser written resignations, in agreed form, by
            each retiring member and deputy member of the board of directors of
            the Group Companies listed in Exhibit 6.2(v) hereof,

<PAGE>
                                                                              15

            including a confirmation from each such person that he has no claims
            against the relevant Group Company resulting from his position as a
            member or deputy member of the board of directors of any of the
            Group Companies; and

      (vi)  deliver to the Purchaser the final audited consolidated statutory
            accounts of the Group prepared in accordance with Swedish GAAP for
            the financial year 2004.

6.3   At Completion, the Purchaser shall:

      (i)   pay to the Vendor the Completion Payment in accordance with Section
            3.1 above;

      (ii)  procure that the debt of Atos Medical AB to Perbio Science Sweden
            Holdings AB in the amount of approximately SEK 61,655,000 resulting
            from the group contribution as of December 31, 2004 is paid in full
            to Perbio Science Sweden Holdings AB by way of transfer of
            immediately available funds.

6.4   At the Completion Date, the Vendor shall cause a shareholders meeting and
      a board meeting to be held in each of the Group Companies allowing the
      Purchaser to appoint new directors and deputy directors and to appoint
      company signatories. The Purchaser shall prepare the minutes of said
      meetings as well as the necessary ancillary documentation, and the
      Purchaser shall procure that the documentation, immediately following said
      meetings, is submitted to the relevant registration authorities, including
      the Swedish Companies Registration Office.

6.5   At the next annual general meeting of each of the Group Companies, the
      Purchaser undertakes to grant the directors in the respective Group
      Companies who have retired the last fiscal year and in connection with the
      Completion, discharge from liability for their administration until the
      Completion Date (or the earlier date of the retirement), however, only
      provided that, in the auditors' reports for the relevant period, the
      Company's auditors do not recommend against such discharges.

<PAGE>
                                                                              16

6.6   To evidence that Completion has taken place in accordance with the terms
      and conditions set forth in this Agreement, the Vendor and the Purchaser
      shall sign a completion memorandum, outlining and evidencing the actions
      taken and the documents delivered in connection with the Completion.

7.    REPRESENTATIONS AND WARRANTIES OF THE VENDOR

      Prior to the date hereof, the Purchaser has conducted a thorough due
      diligence investigations, including but not limited to, a legal,
      accounting and business due diligence with respect to the Group together
      with the Purchaser's professional advisers, to the full satisfaction of
      the Purchaser.

      The Vendor represents and warrants to the Purchaser, subject to all
      matters sufficiently disclosed by the Vendor to the Purchaser and its
      advisors in the Data Room and otherwise in writing during the course of
      the Purchaser's due diligence investigation, that the following statements
      are true and correct as of the Signing Date and, in respect of the
      statements in Sections 7.1, 7.2 and 7.3 only, will be true and correct
      also as of the Completion:

7.1   SHARE CAPITAL AND THE GROUP

7.1.1 The shares of the Group Companies have been duly authorized, validly
      issued, fully paid up, and are owned, directly and indirectly, by the
      Vendor, all as set out in Exhibit 7.1.1 hereto.

7.1.2 There is no agreement or commitment outstanding which calls for the
      allotment, issue or transfer of or accords to any person the right to call
      for the allotment or issue of, any shares (including the Shares) or
      securities of any of the Group Companies.

7.1.3 Each Group Company is duly organized and validly existing under the
      relevant laws of its respective country of incorporation and has the full
      power and authority under its articles of association to carry on its
      business as currently being conducted.

<PAGE>
                                                                              17

7.1.4 Each of the Subsidiaries is a wholly owned subsidiary (or a majority owned
      subsidiary in the case of Platon Medical Ltd.) of a Group Company and no
      Group Company owns any shares or other securities or participation
      interest of any kind in any other company or entity.

7.2   TITLE TO SHARES

      The Vendor owns and has good and marketable title to the Shares, which are
      fully paid, free from all liens, charges and other encumbrances. The
      shares of the Subsidiaries are free from all liens, charges and other
      encumbrances.

7.3   CAPACITY

7.3.1 This Agreement and the transactions contemplated hereby have been duly
      authorized by all necessary actions on the part of the Vendor.

7.3.2 The Vendor warrants that it has all powers to enter into and to perform
      its obligations under this Agreement which, when executed, will constitute
      binding obligations of the Vendor in accordance with its terms.

7.4   BOOKS AND RECORDS

      Since September 2003, the statutory books (including all register and
      minute books) of the Group Companies have been maintained in all material
      respects in accordance with applicable law and are, in all material
      respects, true, correct and complete.

7.5   CONDUCT OF BUSINESS

      Except as contemplated by this Agreement, since December 31, 2004 the
      business of the Group has been conducted in all material respects in the
      ordinary course of business consistent with past practice and since such
      date:

      (i)   except as set forth in Exhibit 7.5(i), no Group Company has entered
            into any agreement or undertaking outside the ordinary course of
            business or which are not on arms length terms;

      (ii)  no Group Company has sold or transferred or committed to sell or
            transfer any material asset other than in the ordinary course of
            business; and

<PAGE>
                                                                              18

       (iii) no Group Company has declared any dividends or made any other
             non-cash payments or distributions to any person or entity outside
             the Group (including, but not limited to, group contributions) in
             respect of any shares or other equity interests.

7.6    LICENSES AND PERMITS

       To the Vendor's Knowledge, the Group Companies have all the necessary
       material licenses, permits and authorizations to carry on their
       businesses as presently being conducted and the Group has not received
       any written notices of non-compliance or to the effect that any such
       material license, permit or authorization is being revoked, withdrawn or
       not renewed.

7.7    COMPLIANCE WITH LAWS

       To the Vendor's Knowledge, the Group Companies have in all material
       respects complied with all applicable laws, regulations and orders
       relating to the business of the Group and otherwise.

7.8    REAL ESTATE

       The Group does not own any real property.

7.9    ENVIRONMENTAL MATTERS

       To the Vendor's Knowledge, no Group Company has since September 2003
       received any notice of any breach of any applicable environmental laws,
       regulations or orders.

7.10   INTELLECTUAL PROPERTY

7.10.1 The Intellectual Property Rights set out in Exhibit 7.10.1 comprise all
       material Intellectual Property Rights that are owned by the Group.

7.10.2 To the best of the Vendor's Knowledge the Group has not been notified of
       any third party challenging the validity of any Intellectual Property
       Rights and neither has to the best of Vendor's Knowledge the Group
       received any written claim whether for infringement, damages or otherwise
       made by any third party which relates to the ownership or use of the
       Intellectual Property Rights by the Company.
<PAGE>

                                                                              19

7.10.3  Except as set forth in Exhibit 7.10.3, to the Vendor's Knowledge, there
        is no ongoing infringement of any material Intellectual Property Rights.

7.11    MATERIAL CONTRACTS

        To the Vendor's Knowledge, no Group Company is in material breach of any
        provision of, or in material default under, any Material Contract, and
        none of the Group Companies has received, or delivered itself, any
        notice of termination of any Material Contract, except in respect of the
        agreement with Obtech Medical AG. To the Vendor's Knowledge no other
        party is in default under or in breach or violation of, any Material
        Contract.

7.12    TAXES

        The Group has filed all tax returns required to be filed and has duly
        paid all taxes required to be paid.

7.13    LITIGATION

        Except as disclosed in Exhibit 7.10.3 and other than in respect of
        normal debt collection proceedings, no Group Company is engaged in any
        litigation or arbitration, whether as a plaintiff, defendant or
        otherwise which could have a material adverse effect on the Group and,
        to Vendor's Knowledge, no litigation or arbitration, by or against a
        Group Company is threatened which could have a material adverse effect
        on the Group.

7.14    EMPLOYEES

7.14.1  There is no actual or, to the Vendor's Knowledge, threatened (i) labor
        strike, work stoppage or lockout against any Group Company; or (ii)
        unfair labor practice charge or complaint against any Group Company
        before any governmental authority.

7.14.2  There are no severance agreements or arrangements with respect to any
        Key Employee other than as reflected in the Data Room. Other than as
        reflected in the Data Room, there are no material plans or programs
        relating to retirement, compensation, incentive, bonus, stock

<PAGE>
                                                                              20

        option, stock purchases or restricted stock operated by any Group
        Company.

7.14.3  Except as described in Exhibit 7.14.3, no bonus or similar arrangement
        related to the consummation of the transaction contemplated by this
        Agreement exists with respect to any employee of the Group.

7.15    BROKERS

        No broker, finder or investment banker is entitled to any brokerage fee,
        finder's fee or other fee from the Group in connection with the
        transaction contemplated by this Agreement.

7.16    INTRA GROUP ARRANGEMENTS

        No Group Company is a party to any contract or arrangement of any kind
        outside the ordinary course of business with the Vendor or its
        affiliates or any director, officer or employee of the Vendor.

7.17    NO CONFLICT

        To the Vendor's Knowledge, the execution of this Agreement by the
        Vendor, the consummation of the transactions contemplated hereby and the
        fulfilment of the terms hereof will not violate any applicable law,
        rule, regulation, judgment, decree, order or approval of any court or
        governmental authority applicable to the Vendor or the Group Companies,
        or by which their respective assets are bound or affected.

7.18    INFORMATION

        The Data Room has been compiled by the Vendor based on questions and
        requests from the Purchaser after due inquiry with the Key Employees. To
        the Vendor's Knowledge, the information provided in the Data Room is,
        taken as a whole, in all material respects, true and correct and not
        misleading and no material information requested by the Purchaser to
        which the Vendor had access has been withheld by the Vendor.

<PAGE>
                                                                              21

8.      REPRESENTATIONS AND WARRANTIES OF THE PURCHASER

8.1     The Purchaser is duly organized and validly existing under the laws of
        Sweden, having all licenses, authorizations and corporate powers to
        carry on its business as now conducted and to enter into this Agreement,
        which, when executed, will constitute binding obligations on the
        Purchaser in accordance with its terms.

8.2     The Purchaser is neither prohibited nor restrained by its by-laws,
        articles of association or similar document, or by any agreements to
        which it is a party, from entering into this Agreement and consummating
        the transactions contemplated hereby, and this Agreement and the
        transactions related hereto have been duly authorized by all necessary
        corporate actions.

8.3     The Purchaser has no actual knowledge of any breach of any warranty in
        Section 7 of this Agreement.

9.      REMEDIES

9.1     Except for the warranties contained in Sections 7.1, 7.2 and 7.3, none
        of the warranties contained in this Agreement shall survive after the
        date hereof and no Party shall under any circumstance have any rights or
        remedies directly or indirectly against the other Party or its
        affiliates, officers, directors, employees, agents or representatives
        for any breach of warranty contained in this Agreement nor shall the
        Vendor, the Purchaser or any of their respective affiliates, officers,
        directors, employees, agents or representatives have any liability on
        account of such breach. Each of the Parties confirm that the principles
        for establishing the purchase price for the Shares have been agreed
        based on this principle.

9.2     The Vendor is, subject to what is set out below in this Section 9,
        liable for breach of the warranties contained in Sections 7.1, 7.2 and
        7.3. Any compensation payable by the Vendor for a breach there under
        shall only be in the form of a reduction of the Final Purchase Price and

<PAGE>
                                                                              22

        the Vendor's aggregate liability to compensate the Purchaser shall under
        no circumstances exceed the Final Purchase Price.

9.3     The Purchaser confirms that it has not relied on any express or implied
        warranty, representation, indemnity, covenant or undertaking which is
        not expressly contained in this Agreement.

9.4     The remedy provided to the Purchaser under this Agreement shall be
        exclusive and hence it is specifically agreed that the Vendor shall have
        no other liability in respect of this Agreement including any liability
        under any statute including the Swedish Sale of Goods Act (Sw. Koplagen
        (1990:931)) or the International Sale of Goods Act (Sw. Lag (1987:822)
        om internationella kop).

10.     INTERIM MEASURES

10.1    As soon as practicable after the Signing Date, representatives of the
        Vendor, the Purchaser and the CEO of the Company shall form a joint
        committee with the purpose to outline any and all issues that need to be
        resolved in order for the Group to be able to operate on a stand alone
        basis immediately after the Completion Date. The intent is that all such
        issues shall be resolved by the Group reaching separate agreements with
        third parties. However, in case where such agreements cannot be reached,
        each of the Vendor and the Purchaser undertake to use best efforts in
        order to agree on a temporary separation agreement. Any separation
        agreement shall be on arm's length terms on market conditions and shall,
        unless the Parties agree otherwise, be conditioned upon Completion and
        not be effective for a longer term than three months after the
        Completion Date.

10.2    The Vendor agrees to extend its property insurance coverage to include
        the Group for a period of thirty (30) days after the Completion Date. In
        no instance shall Vendor's obligations exceed the terms or limits of its
        current worldwide property policy. The Purchaser shall be responsible
        for all non-covered property losses, including self-insured retentions,
        and shall reimburse and indemnify the Vendor for any and all costs
        incurred by the Vendor or its affiliates as a result of such continued
        insurance coverage.

<PAGE>
                                                                              23

10.3    The Purchaser shall procure that the Vendor is given opportunity to have
        reasonable access and assistance from the Company, including but not
        limited to Tommy Niklasson, for the preparation of the statutory
        accounts for 2004 and associated tax filings etc. of the companies
        within the former Perbio Science Group during a period of nine (9)
        months from the Completion Date. The Parties shall during the period
        between the signing Date and the Completion Date establish the
        reasonable time limits and other terms and conditions for such work and
        both parties undertake to use best efforts to reach an agreement
        relating hereto on arm's length terms reasonably acceptable to both
        Parties.

11.     COSTS AND EXPENSES

        Except as expressly otherwise provided herein, the Vendor and the
        Purchaser, respectively, shall bear their own costs and expenses
        incurred in connection with this Agreement and the transactions
        contemplated herein, whether or not such transactions shall be
        completed, including, without limitation, all fees of its legal
        advisors, accountants and other advisors.

12.     CONFIDENTIALITY

        The Vendor and the Purchaser undertake not to disclose the content of
        this Agreement or any other information, whether written or oral,
        including, without limitation, financial information, trade secrets,
        client lists and other proprietary business information, regarding the
        Company, which information is not known to the general public, unless
        (i) required to do so by law or stock exchange recommendations or
        regulations or (ii) such disclosure has been consented by the Vendor or
        the Purchaser, as the case may be.

<PAGE>
                                                                              24

13.     ANNOUNCEMENTS

        The Parties shall mutually determine the date and the form of any
        announcement of the Purchaser's acquisition of the Shares except as may
        be required by law or stock exchange recommendations or regulations in
        which case such Party undertakes to inform the other Party in advance in
        writing.

14.     ASSIGNMENTS

        This Agreement shall be binding upon and inure to the benefit of the
        successors and assignees of the Parties but shall not be assignable by
        any of the Parties without the prior written consent of the other Party.

15.     ENTIRE AGREEMENT AND AMENDMENTS

15.1    This Agreement constitutes the entire understanding of the Parties and
        supersedes all prior agreements, covenants, arrangements,
        communications, representations or warranties, whether oral or written,
        by any officer, employee, representative or advisor of either of the
        Parties or the Company.

15.2    This Agreement may only be amended by an instrument in writing duly
        executed by the Parties. No change, termination or modification of any
        of the provisions of this Agreement shall be binding on the Parties,
        unless made in writing in accordance with this Section 15.2.

16.     NOTICES

        All notices, consents and other communications required or permitted
        under this Agreement shall be made in writing and be deemed to have been
        duly given by the Parties if addressed and delivered by registered mail
        to the addresses set forth below or to such other addresses as may be
        given by written notice in accordance with this Section 16.

<PAGE>
                                                                              25

        If to the Vendor:

        Perbio Science International Netherlands B.V.
        Att: John Dellapa
        Fisher Scientific International Inc
        Liberty Lane
        Hampton, NH 03842
        USA

        with a copy to:

        Advokatfirman Hammarskiold & Co
        Att: Jacob Melander
        Box 2278
        103 17 Stockholm, Sweden

        If to the Purchaser:

        Cidron Group AB
        Att: Director
        C/o NC Advisory AB
        Stureplan 4A
        114 35 Stockholm, Sweden

        with a copy to:

        White & Case Advokat AB
        Att: Claes Zettermarck
        Box 5573
        114 85 Stockholm, Sweden

17.     INVALIDITY

        If any term or provision in this Agreement shall be held to be illegal
        or unenforceable, in whole or in part, under any enactment or rule of
        law, such term or provision or part shall to that extent be deemed not
        to

<PAGE>
                                                                              26

        form a part of this Agreement but the enforceability of the remainder of
        this Agreement shall not be affected.

18.     WAIVER

        No waiver by any of the Parties of any of the requirements hereof or of
        any of its rights hereunder shall have effect unless given in writing
        and signed by the duly authorized representatives of the other Parties.

19.     GOVERNING LAW AND DISPUTES

19.1    This Agreement shall be governed by and construed in accordance with the
        laws of Sweden.

19.2    Any dispute, controversy or claim arising out of or in connection with
        this Agreement, or the breach, termination or invalidity thereof, shall
        be finally settled by arbitration in accordance with the Rules of the
        Arbitration Institute of the Stockholm Chamber of Commerce.

19.3    The place of arbitration shall be Stockholm. The language to be used in
        the arbitration proceedings shall be English.

The Parties hereto have executed this Agreement on the day and year first
written above in two original copies, of which each of the Parties hereto have
taken one each.

PERBIO SCIENCE INTERNATIONAL
NETHERLANDS B.V.                             CIDRON GROUP AB

by                                           by

/s/ John A. Dellapa                          /s/ Ulf Johnansson by proxy
-------------------------                    -----------------------------
John A. Dellapa                              Ulf Johnansson by proxy

<PAGE>
                                                                              27

Fisher Scientific International Inc. hereby represents and warrants to the
Purchaser that the statements contained in Sections 7.1, 7.2 and 7.3 are true
and correct as of the Signing Date and will be true and correct also as of the
Completion. For the avoidance of doubt, it is confirmed that Section 19 applies
to this representation and warranty.

FISHER SCIENTIFIC INTERNATIONAL INC.

by

/s/ Paul M. Meister
-------------------------
Paul M. Meister

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