Document:

EXCLUSIVE
LICENSE AGREEMENT

 

THIS
EXCLUSIVE LICENSE AGREEMENT (the “Agreement”), effective as of this 29th day of March, 2017, between KOTZKER
CONSULTING LLC, a Delaware limited liability company having a business address of 20 Highview Ln, Yardley, PA 19067 (the “LICENSOR”)
and INTIVA KOTZKER PHARMACEUTICALS INC., a Colorado corporation having a business address at 3773 Cherry Creek North Drive,
Suite 575, Denver Colorado 80209 (the “LICENSEE”).

 

RECITALS

 

WHEREAS,
LICENSOR owns or has exclusively licensed all right, title and interest in certain Licensed Technology (as hereinafter defined),
for the use of cannabinoids alone or in combination with various other active pharmaceutical ingredients and/or excipients (i)
as preventative and therapeutic neuroprotectives against nerve agents and pesticides and (ii) for the treatment of diseases for
a variety of therapeutic categories;

 

WHEREAS,
LICENSOR desires to license LICENSOR’s right, title and interest in the Licensed Technology in the Licensed Field and in
the Territory (as hereinafter defined), and LICENSEE desires to secure such license in order to develop, commercialize, sell,
and license throughout the Territory products that embody or employ the Licensed Technology;

 

NOW
THEREFORE, in consideration of the premises, and the receipt of good and valuable consideration the sufficiency of which is hereby
acknowledged, the parties hereto agree as follows:

 

1.
DEFINITIONS

 

1.1
“Accounting Period” shall mean each 3 month period ending March 31, June 30, September 30, and December 31
during the term of this Agreement.

 

1.2
“Affiliate” with respect to each party shall mean any corporation or other legal entity controlling, controlled
by, or under common control with such party. The term “control” means possession, direct or indirect, of the powers
to direct or cause the direction of the management and policies of an entity, whether through the ownership of voting securities,
by contract or otherwise.

 

1.3
“Approval” shall mean such approval or approvals as are necessary from an applicable Regulatory Authority for
the marketing of the Products for use in the Licensed Field in a jurisdiction within the Territory.

 

1.4
“Effective Date” shall mean the date first written above.

 

    	CONFIDENTIAL	1	 

    	 

    

 

1.5
“FDA” shall mean the United States Food and Drug Administration and any successor thereto.

 

1.6
“First Commercial Sale” shall mean the first sale of any Licensed Product by LICENSEE, its Affiliates or Sublicensees,
but not including transfers or dispositions of Licensed Product for charitable, promotional, pre-clinical, clinical, regulatory
or governmental purposes for which LICENSEE receives no payment.

 

1.7
“License” shall have the meaning ascribed to that term in Section 2.1(a).

 

1.8
“Licensed Field” the use of cannabinoids alone or in combination with various other active pharmaceutical ingredients
and/or excipients (i) as preventative and therapeutic neuroprotectives against nerve agents and pesticides and (ii) for the treatment
of diseases for a variety of therapeutic categories.

 

1.9
“Licensed Inventions” shall mean the inventions claimed in the Licensed Patents.

 

1.10
“Licensed Know-how” shall include all technology, materials, research data, designs, formulas, process information,
manufacturing information, application information, commercialization information, clinical data, scientific data, medical data,
and any other information useful from time to time for the design, development, manufacturing, use, and/or commercialization of
the Licensed Products, whether or not eligible for protection under the patent laws of the United States or elsewhere and whether
or not any such technology, materials, information, data and the like related thereto, would be enforceable as a trade secret
or the copying of which would be enjoined or restrained by a court as constituting unfair competition, which is developed by,
or in the possession or control of, LICENSOR now or at any time during the term of this Agreement other than such information
that is independently developed by LICENSEE or its agents, as evidenced by contemporaneous written records.

 

1.11
“Licensed Patents” shall mean any and all rights arising out of or resulting from (i) the patents and patent
application set forth in Schedule 1.11 attached to this Agreement, as well as any additional patents or patent applications related
to any aspect of any Licensed Technology Improvements, Licensed Know-how, Licensed Products, and/or Licensed Technology (as herein
defined) filed prior to or during the term of this Agreement and (ii) any letters patent granted in respect of all such applications,
as well as, without limitation, any substitutions, divisions, continuations, continuations-in-part, reissues, renewals, re-examinations,
extensions, supplementary protection certificates, confirmations, registrations, revalidations and the like, of any and all such
patents and patent applications and any international equivalents thereof.

 

1.12
“Licensed Products” shall mean any and all products, (including any and all) doses, strengths, formulations,
compositions and methods thereof containing cannabinoids alone or in combination with various other active pharmaceutical ingredients
and/or excipients for use in the Licensed Field utilizing the Licensed Technology.

 

1.13
“Licensed Technology” shall mean the aggregate of the Licensed Inventions, the Licensed Know-how, the Licensed
Products and the Licensed Patents and any other information and/or technology related to the Licensed Products and/or the design
and/or the manufacturing of the Licensed Products.

 

    	CONFIDENTIAL	2	 

    	 

    

 

1.14
“Licensed Technology Improvements” shall have the meaning ascribed to that term in Section 2.2.

 

1.15
“Net Sales” shall mean the Gross Sales (as defined and calculated in accordance with US generally accepted
accounting principles (“GAAP”) of Licensed Products by LICENSEE or any of its Affiliates or Sublicensees (“Sellers”)
to a third party that is not an Affiliate or Sublicensee of LICENSEE (“Customer”), less applicable Sales Returns
and Allowances (as defined below), and corresponding to the definition of actual net sales used in the audited consolidated financial
statements of LICENSEE:

 

1.16
“Sales Returns and Allowances” means the sum of

 

	 	(a)	(i)
    as determined under US GAAP, trade, cash, and quantity discounts or rebates (other than price discounts granted at the time
    of invoicing and which are included in the determination of Gross Sales), credits or allowances given or made for rejection
    or return of, and for uncollectible amounts on, previously sold Licensed Products or for retroactive price reductions (including
    any types of rebates and charge-backs), (iii) taxes, duties, or other governmental charges levied on or measured by the billing
    amount for Licensed Products, and (iv) credits for allowances given or made for wastage, replacement, indigent patient, and
    any other sales programs for Licensed Products; and
	 	(b)	periodic
    adjustments of the amount determined in (a) to reflect amounts actually incurred by LICENSEE for items (i), (ii), (iii), and
    (iv) in clause (a).

 

For
purposes of determining Gross Sales, a “sale” shall not include transfers or dispositions for charitable, promotional
purposes or for pre-clinical, clinical, regulatory or governmental testing purposes for which a Seller receives no payment.

 

If
a Seller commercially uses or disposes of any Licensed Product by itself (as opposed to use or disposition of the Licensed Product
as a component of a combination of active functional elements) other than in a bona fide sale to a bona fide Customer, the Gross
Sales price of the Licensed Product for purposed of calculating Gross Sales shall be the price which would be then payable in
an arm’s length transaction with such a Customer. If a Seller commercially uses or disposes of any Licensed Product as a
component of a combination of active functional elements other than in a bona fide sale to a bona fide Customer, the Gross Sales
price of the Licensed Product for purposes of calculating Gross Sales shall be determined in accordance with the definition of
“Sales Returns and Allowances” above, using as the Gross Sales price of the combination that price which would then
be payable in an arm’s length transaction.

 

Transfer
of a Licensed Product within a Seller or between or among LICENSEE and its Affiliate and Sublicensees for sale by the transferee
shall not be considered a sale, commercial use or disposition for the purpose of the foregoing subsections; in the case of such
transfer the Gross Sales price shall be the Gross Sales price of the Licensed Product when sold to a third party by the transferee.

 

    	CONFIDENTIAL	3	 

    	 

    

 

1.16
“Patent Right” shall mean any right, title or interest in any Licensed Patent.

 

1.17
“Regulatory Authorities” shall mean the governmental authorities responsible for regulating the development,
marketing, and/or sales of pharmaceutical products in a particular country.

 

1.18
“Seller” shall mean with respect to any sale of a Licensed Product the party responsible for such sale, where
such party may be, as applicable, LICENSEE, an Affiliate of LICENSEE or a Sublicensee.

 

1.19
“Sublicensee” shall mean any unrelated third party licensed by LICENSEE or by an Affiliate thereof to develop
or have developed, make or have made, use or have used, sell or have sold, import or have imported any Licensed Product. For the
avoidance of doubt, a wholesaler, distributor, or similar entity which purchases any Licensed Product from LICENSEE or any of
its Affiliates in a bona fide arms-length transaction, shall not be deemed to be a Sublicensee. The agreement evidencing such
sublicense shall contain relevant terms and conditions substantially similar to those in this Agreement and shall be subject to
the review and approval by LICENSOR, such approval not to be unreasonably withheld. Notwithstanding the foregoing, if LICENSEE
sublicenses to a third party who has financial wherewithal equal to or greater than the LICENSEE, the approval of LICENSEE shall
not be required.

 

1.20
“Term” shall mean the period during which this Agreement is in effect, commencing on the Effective Date and
continuing until the termination of this Agreement.

 

1.21
“Territory” shall mean the World.

 

1.22
“Valid Claim” shall mean any pending or issued claim of any patent application or patent that has not been
finally rejected or declared invalid or unenforceable by a patent office or court of competent jurisdiction in any unappealed
and unappealable decision. Notwithstanding other provisions of this Agreement, if a claim of a pending patent application within
the Licensed Patents has not issued as a claim of an issued patent within the Licensed Patents in any particular country in the
Territory, within ten (10) years after the initiation of the examination from which such claim takes priority, such pending claim
shall not be a Valid Claim in such country in the Territory for purposes of this Agreement.

 

2.
LICENSE

 

2.1
Grant of License. Subject to the provisions of this Agreement, LICENSOR hereby grants LICENSEE, including LICENSEE’s
Affiliates,

 

(a)
a royalty-bearing, Territory-wide license (the “License”) in the Licensed Field under the Patent Rights to the Licensed
Technology, as well as under the Licensed Patents, the Licensed Know-how, and the Licensed Technology, regardless of whether such
Licensed Patents are actually granted, to use the Licensed Know-how and Licensed Technology and to develop and have developed,
make and have made, use and have used, sell and have sold, offer for sale and have offered for sale, import and have imported,
export and have exported, any and all inventions claimed in the Licensed Patents related to the Licensed Products and/or any compounds,
chemicals, substrates, devices, tools, dies, molds or any other materials whatsoever that are useful in the development and/or
manufacturing and/or sale of the Licensed Products, and particularly including, without limitation, such license to develop and
have developed, make and have made, use and have used, sell and have sold, offer for sale and have offered for sale, import and
have imported, export and have exported Licensed Products, which license shall be exclusive even as to LICENSOR, and

 

    	CONFIDENTIAL	4	 

    	 

    

 

(b)
the parties acknowledge and agree that LICENSEE is permitted to seek funding for the development of the Licensed Product, from
an Affiliate or funding source without receipt of such funds being deemed a sale or sublicense that would entitle LICENSOR to
receive any portion of the particular funding , and

 

(c)
the right to grant bona fide sublicenses to third parties, to develop and have developed, to make and have made, use and have
used, sell and have sold, import and have imported, export and have exported, Licensed Products, and to exercise all other rights
under the License; provided, however, LICENSEE shall not have the right to grant any sublicense or to transfer any of its
rights under the License unless each such sublicense or other transfer granted by LICENSEE contains terms and conditions under
which the Sublicensee or transferee will be bound in the same manner as LICENSEE is under this Agreement. A copy of the proposed
agreement shall be provided to LICENSOR prior to the execution of the Agreement.

 

2.2
Improvements. The parties acknowledge and agree that this Agreement shall apply to any and all improvements, modifications,
enhancements, or other changes to the Licensed Technology created, conceived, developed, or reduced to practice by LICENSOR during
the term of this Agreement within the Licensed Field (collectively, the “Licensed Technology Improvements”). Licensed
Technology Improvements within the Licensed Field shall be considered to be a part of the Licensed Technology and shall be licensed
to LICENSEE in accordance with the provisions of this Agreement.

 

3.
DEVELOPMENT OBLIGATIONS

 

3.1
LICENSEE’s Obligations. LICENSEE shall use its commercially reasonable efforts to develop and commercialize
the Licensed Products, and, in particular, LICENSEE will be responsible for the design, manufacturing, preclinical, clinical,
and regulatory development activities of the Licensed Products in the Territory and shall bear the costs of such activities. LICENSEE
shall be responsible for the good laboratory practices (“GLP”) and/or GLP pre-clinical toxicology studies,
good manufacturing practices (“GMP”), GMP manufacturing of the Licensed Products, including the development
of associated compounds, chemicals, substrates, devices, tools, dies, molds, and or related materials. In addition, the parties
may elect to perform non-GLP pre-clinical toxicology studies as a prelude to GLP studies. In the event that LICENSEE, after using
its commercially reasonable efforts, decides to halt or stop development, the termination provisions of Section 9 below shall
apply.

 

    	CONFIDENTIAL	5	 

    	 

    

 

3.2
Progress Reports. At intervals no longer than every six (6) months, LICENSEE shall provide a written summary status
report of progress made toward commercialization, summarizing achievements toward commercialization in the last six months and
communicate with LICENSOR by telephone or through in-person meetings on progress made toward achieving the development and commercialization
of one or more Licensed Products.

 

3.3
Cooperation of LICENSOR. Upon execution of the Agreement, LICENSOR, in consideration of the various continuing payment
obligations of LICENSEE under Article 5 (Royalties and Milestone Payments and Equity Interest) and Article 9 (Termination), shall
provide to LICENSEE such assistance, and cooperation as shall be requested and pre-authorized in writing by LICENSEE relating
to the development and commercialization of Licensed Products, such assistance and cooperation will be provided by LICENSOR to
LICENSEE at a rate of $250/hour for consultant time and a minimum retainer of two (2) hours a month. LICENSEE shall, as it deems
necessary, separately contract with LICENSOR for consulting services regarding the design and/or manufacturing and/or commercialization
and/or general business purposes of the Licensed Products. The terms of such consulting agreement to be mutually agreed but will
include a rate of $250/hour for consultant time and a minimum retainer of two (2) hours a month and guaranteed availability of
ten (10) hours per month, being paid within 30 days of invoicing, and will be terminable by either party on sixty (60) days written
notice. All other terms to be separately negotiated between LICENSOR and LICENSEE.

 

3.4
Provision of Product in Support of Development and Sales. LICENSEE will manufacture or will have manufactured the
finished and packaged Licensed Products in support of development activities and for commercial sales.

 

4.
FILING, PROSECUTION AND MAINTENANCE OF LICENSED PATENTS

 

4.1
Responsibility. LICENSEE, at its expense, shall be responsible, and shall have sole decision-making authority, for
the preparation, filing, prosecution and maintenance of all patent applications and patents included in the Licensed Patents;
provided, however, that if the LICENSEE determines to cease the preparation, filing, prosecution or maintenance of any
patent application or patent included in the Licensed Patents, then LICENSOR, at its option and expense, shall have the right
to assume responsibility for such preparation, filing, prosecution and maintenance. Prior to abandoning any patent application,
Licensee will provide Licensor an adequate opportunity to assume such prosecution at its own expense before the application goes
abandoned.

 

4.2
Delivery of Existing Documents. With respect to each Licensed Patent, each document or a draft thereof pertaining
to the filing, prosecution, or maintenance of such Licensed Patent, including, without limitation, each patent application, office
action, response to office action, request for terminal disclaimer, request for reissue or reexamination of any patent issuing
from such application, and all other prosecution items contained in the file maintained by or for LICENSOR in respect of such
Licensed Patent in the possession of LICENSOR or its counsel at the Effective Date shall be provided to LICENSEE within fifteen
(15) days of the Effective Date and any such documents received by LICENSOR or its counsel from any patent office after the Effective
Date shall be provided within fifteen (15) days after receipt.

 

    	CONFIDENTIAL	6	 

    	 

    

 

5.
ROYALTIES, MILESTONE PAYMENTS AND EQUITY

 

5.1
Royalties. Beginning with the First Commercial Sale in any country of any Licensed Product by LICENSEE or any of
its Affiliates or Sublicensees, LICENSEE shall pay to LICENSOR royalties in accordance with the following schedule for Licensed
Products sold by LICENSEE or its Affiliates and Sublicensees until the later to occur of (i) the expiration date of the last to
expire of the Licensed Patents; or (ii) when a competitive generic product utilizing the Licensed Technology is marketed in the
particular country in the Territory., LICENSEE will pay to LICENSOR the royalty specified below, for the manufacture, use, sale,
import or offer for sale of such Licensed Product in the country where such manufacture, use, sale, import or offer for sale of
such Licensed Product occurs, infringe a Valid Claim of any Licensed Patent or violate an exclusive marketing right granted by
any governmental agency in such country in the absence of the License granted by Article 2 or a sublicense granted under Article
2:

 

	 	(i)	Three
    percent (3%).
	 	 	 
	 	(ii)	For
    sales of Licensed Products by Sublicensees, ten percent (10%) of the total revenue received by LICENSEE, or any Affiliate
    of LICENSEE, from any other person or organization in the form of royalties, milestone payments or any other consideration
    (including the proportionate share of such non-cash consideration, for example and without limitation, stock, real property,
    and ownership interests) in respect of sublicense(s) granted by LICENSEE or any of its Affiliates under Article 2 (the “Sublicensee
    Revenue) in all countries in the Territory with the exception for Israel where LICENSOR shall receive eighteen percent (18%)
    of the Sublicensee Revenue. Notwithstanding the foregoing, in no event shall LICENSOR receive Sublicensee Revenue that is
    less cumulatively than the three percent (3%) royalty LICENSOR is entitled to if the sale had been made by LICENSEE to the
    Third Party. Additionally, regardless of LICENSEE’s sublicense to a Third Party, LICENSOR shall receive the Milestone
    Payments as set forth in Section 5.2 either from the LICENSOR or the Sublicensee; 
	 	 	 
	 	(iii)
    	To
    the extent funds received by the LICENSEE or any Affiliate, from a Sublicensee or any other source are provided for and used
    for developing Licensed Products, such funds are not considered Sublicensee Revenue under Section 5.1(iii) and such funds
    shall not be subject to any royalty payment whatsoever to LICENSOR.

 

Only
one royalty under this Section 5.1 shall be due and payable to LICENSOR by LICENSEE in respect of the sale of any Licensed Product,
regardless of the number of Valid Claims covering such Licensed Product or any other considerations. Royalty payments shall be
made within sixty (60) days after the end of the Accounting Period in which the sale is made.

 

    	CONFIDENTIAL	7	 

    	 

    

 

5.2
Upfront and Milestone Payments. In addition to the payments provided for in Section 5.1, LICENSEE shall pay LICENSOR
the following amounts upon the occurrence of the following events:

 

	 	●	In
    consideration for access to the Licensed Patents and Licensed Technology, LICENSEE shall make the following payments to LICENSOR:
    

 

LICENSEE
shall be responsible for the patent prosecution expenses from October 1, 2016 through the earlier of the date of execution of
this Agreement or the date that LICENSEE elects to terminate negotiations with respect to this Agreement (the “Patent Expenses”).
The Patent Expenses shall not exceed $15,000. If it executes this Agreement, it shall pay one third (1/3) of the Patents Expenses
upon execution of this Agreement (the “Closing”). One Third (1/3) of the Patent Expenses shall be paid sixty (60)
days following Closing and one third (1/3) of the Patent Expenses shall be paid one hundred twenty (120) days following Closing.

 

	TIME LICENSOR SHALL RECEIVE PAYMENTS	 	PAYMENT	 
	 	 	 	 
	Upon execution of this Agreement (the “Closing”):	 	$	60,000	 
	Sixty (60) days following Closing:	 	$	60,000	 
	One hundred twenty days (120) following Closing:	 	$	60,000	 

 

	 	●	Development
    Milestone payments shall be paid by LICENSEE to LICENSOR as follows:

 

A.
for the “family” of Licensed Products for use as a preventative and therapeutic neuroprotective against nerve agents
and pesticides, LICENSEE shall make a one time payment of $500,000 as follows:

 

i.
$250,000 upon no later than thirty (30) days from acceptance of submission of the regulatory filing of the first Licensed Product
as preventative and therapeutic neuroprotectives against nerve agents and/or pesticides by the applicable Regulatory Authority.

 

ii.
$250,000 upon no later than thirty (30) days from Approval of the first Licensed Product as preventative and therapeutic for use
as neuroprotectives against nerve agents and/or pesticides by the applicable Regulatory Authority.

 

B.
for the treatment of diseases LICENSEE shall make a one-time payment of $500,000 as follows:

 

i.
$250,000 upon no later than thirty (30) days from acceptance of submission of the regulatory filing of the first Licensed Product
for treatment of a disease (i.e. a product that is not as preventative and therapeutic neuroprotectives against nerve agents and/or
pesticides) by the applicable Regulatory Authority.

 

    	CONFIDENTIAL	8	 

    	 

    

 

ii.
$250,000 upon no later than thirty (30) days from Approval of the First Licensed Product for treatment of a disease by the applicable
Regulatory Authority.

 

5.3
Credits for Payments to Third Parties. In the event that LICENSEE and/or LICENSEE’s Affiliate is required
to pay royalties to any third parties with respect to the development or commercialization of a Licensed Product, LICENSEE will
have the right to offset such royalties against any payments owed to LICENSOR pursuant to Section 5.1, provided that no such offset
shall result in a reduction of the royalties owed to LICENSOR pursuant to Section 5.1 to an amount that is less than fifty percent
(50%) of the amount that would otherwise be due in respect of any Accounting Period.

 

5.4
Overdue Payments. The payments due under this Agreement shall, if overdue, bear interest until payment at a per
annum rate equal to the lesser of ten (10) percent and the maximum permitted by law. The payment of such interest shall not preclude
LICENSOR from exercising any other rights it may have as a consequence of the lateness of any payment.

 

5.5
Currency. All royalty payments and milestone payments under this Agreement shall be in United States Dollars. Whenever
conversion from any foreign currency shall be required, such conversion shall be at the rate of exchange thereafter published
in the Wall Street Journal for the business day closest to the end of the applicable Accounting Period.

 

5.6
Equity Interest. In consideration for entering into this Agreement, LICENSOR shall receive , within 30 calendar
days, 31,550 shares of Intiva Inc. (“Intiva”) stock. This number reflects approximately one half of one percent of
the amount of shares outstanding as of the date of this Agreement.

 

Upon
approval of the first Licensed Product, LICENSOR shall be issued US$180,000 value of Intiva’s stock based upon the share
price determined at the most recent private placement price per share with an unrelated third party, or if Intiva shares are publicly
traded the average closing price for the previous 30 days (the “Additional Stock”). For purposes of illustration,
if in the last private placement with an unrelated third party, the par share value of Intiva’s stock was equal to $5.00
per share, LICENSOR shall be issued 36,000 share of Additional Stock.

 

If
the parties determine that the development of the Licensed Product is unfeasible, as demonstrated by the failure to develop a
formulation or to establish a satisfactory regulatory pathway or a determination that the formulation to be Marketed may not be
economically viable, but LICENSEE elects to acquire an interest in the Licensed Patents, in consideration for LICENSEE continuing
to pay the cost of prosecuting the Licensed Patents and the issuance to LICENSOR of the Additional Stock referenced above which
would not otherwise be issued to LICENSOR, LICENSOR and LICENSEE shall at the time LICENSEE elects to no longer seek to develop
the Product agree that LICENSEE shall acquire a twenty five percent (25%) interest in the Licensed Patents, provided that LICENSEE
has paid LICENSOR $180,000.

 

    	CONFIDENTIAL	9	 

    	 

    

 

6.
REPORTS AND PAYMENTS

 

6.1
Books of Accounts. LICENSEE shall keep, and shall cause each of its Affiliates and Sublicensees, if any, to keep
full and accurate books of accounts containing all particulars that may be necessary for the purpose of calculating all royalties
payable to LICENSOR. Such books of account shall be kept at their principal place of business and, with necessary supporting data
shall, during all reasonable times for the two (2) years next following the end of the calendar year to which each shall pertain,
be open for inspection at reasonable times by LICENSOR or its designee at LICENSOR’s expense for the purpose of verifying
royalty statements or compliance with this Agreement. In the event that any audit performed under this Section 6.1 reveals an
underpayment in excess of seven and one half percent (7.5%) of the total amount determined by the auditor to be due LICENSOR (the
“Underpayment”), LICENSEE shall bear the full cost of such audit and shall remit any amounts due to LICENSOR within
forty-five (45) days of receiving notice thereof from LICENSOR. LICENSOR shall have the right to audit yearly, provided however
if such audit reveals an Underpayment, LICENSOR shall thereafter have the right to audit on a semi-annual basis (with the audit
returning to a yearly basis after three (3) sequential semi-annual audits are conducted with no Underpayments discovered).

 

6.2
Quarterly Payments. In each year the amount of royalty due shall be calculated on a cash received basis on the Licensee
and Affiliates and Sublicensees books as of the end of each Accounting Period as defined in Section 1.1 of this Agreement and
shall be paid within the next sixty (60) day period following such date, every such payment to be supported by the accounting
prescribed in Section 6.3.

 

6.3
Accounting Reports. With each quarterly payment, LICENSEE shall deliver to LICENSOR a full and accurate accounting
to include at least the following information:

 

(a)
Quantity of each Licensed Product sold by LICENSEE and its Affiliate or Sublicensees (by country);

 

(b)
Inventory of each Licensed Product at end of each period held by LICENSEE and its Affiliate or Sublicensees (by country);

 

(c)
Gross Sales billed and Net Sales received by LICENSEE or any of its Affiliates or Sublicensees (“Sellers”) for the
sale of each Licensed Product with full detail of Sales Returns and Allowances used to determine the Net Sales;

 

(d)
Names and addresses of all Sublicensees of LICENSEE; and

 

(e)
Total Royalties payable to LICENSOR.

 

    	CONFIDENTIAL	10	 

    	 

    

 

7.
INFRINGEMENT

 

7.1
Infringement of Licensed Patents. Each party shall promptly notify the other party of evidence of infringement of
a claim of a Licensed Patent by a third party. If either party shall have supplied the other party with written evidence demonstrating
prima facie infringement of a claim of a Licensed Patent in the Licensed Field by a third party, LICENSEE shall have the right
to take steps to protect the Patent Right in such claim, either upon notice from LICENSOR requesting such action, or on its own
initiative. LICENSEE shall notify LICENSOR, within three (3) months of one party providing the other with evidence of infringement,
whether LICENSEE intends to prosecute the alleged infringement. If LICENSEE notifies LICENSOR that it intends to so prosecute,
LICENSEE shall (at its expense), within three (3) months of its notice to LICENSOR either (i) cause infringement to terminate
or (ii) initiate and diligently prosecute legal proceedings against the infringer and in LICENSOR’s name if so required
by law. In the event LICENSEE notifies LICENSOR that LICENSEE does not intend to prosecute said infringement, LICENSOR may, upon
notice to LICENSEE, initiate legal proceedings against the infringer at LICENSOR’s expense. No settlement, consent judgment,
or other voluntary final disposition of the suit which invalidates or restricts the claims of such Patent Rights may be entered
into without the consent of the other party, which consent shall not be unreasonably withheld, but provided that, in the event
one party (“the Objecting Party”) withholds consent for a proposed settlement, the party proposing the settlement
may decline to support further costs of such suit or settlement discussions, and the Objecting Party shall be required to continue
such suit or settlement discussions at its own expense. LICENSEE shall indemnify LICENSOR against any order for payment that may
be made against LICENSOR in such proceedings brought by LICENSEE. LICENSOR shall indemnify LICENSEE against any order for payment
that may be made against LICENSEE in such proceedings brought by LICENSOR to the extent arising out of any proceedings which LICENSOR
brings at its own expense pursuant to Section 7.1 following LICENSEE’s decision not to prosecute any alleged infringement.

 

7.2
Cooperation. In the event one party shall initiate or carry on legal proceedings to enforce any Patent Right against
any alleged infringer, the other party shall fully cooperate with and supply all assistance reasonably requested by the party
initiating or carrying on such proceedings. The party which institutes any suit to protect or enforce a Patent Right shall have
sole control of that suit and shall bear the reasonable expenses (including legal fees) incurred by said other party in providing
such assistance and cooperating as is requested pursuant to this Section. The party initiating or carrying on such legal proceedings
shall keep the other party informed of the progress of such proceedings and said other party shall be entitled to counsel in such
proceedings but at its own expense. Any award paid by third parties as the result of such proceedings (whether by way of settlement
or otherwise) shall first be applied to reimbursement of the unreimbursed legal fees and expenses incurred by either party and
then the remainder shall be divided between the parties as follows:

 

(a)
If the amount is based on lost profits, LICENSEE shall receive an amount equal to the damages the court determines LICENSEE has
suffered as a result of the infringement less the amount of any royalties that would have been due LICENSOR on sales of Licensed
Product lost by LICENSEE as a result of the infringement had LICENSEE made such sales, and LICENSOR shall receive an amount equal
to the royalties it would have received if such sales had been made by LICENSEE, and

 

(b)
As to awards other than those based on lost profits, sixty percent (60%) to the party initiating such proceedings and forty percent
(40%) to the other party.

 

    	CONFIDENTIAL	11	 

    	 

    

 

7.3
Infringement Actions by Third Parties. In the event that the making, selling or using of a Licensed Product in the
Licensed Field infringes the intellectual property rights of others, LICENSEE will have the first right to control any negotiation
or litigation with respect thereto; however no settlement, consent judgment or other voluntary final disposition of the infringement
allegation may be entered into without the written consent, which shall not be unreasonably withheld, of LICENSOR.

 

7.4
Further Assurances; Progress Reports. For the purpose of the proceedings referred to in this Article 7, LICENSOR
and LICENSEE shall permit the use of their names and shall execute such documents and carry out such other acts as may be necessary.
The party initiating or carrying on such legal proceedings shall keep the other party informed of the progress of such proceedings
and said other party shall be entitled to counsel in such proceedings but at its own expense, said expenses to be offset against
any damages received by the party bringing any infringement suit against a third party in accordance with Section 7.2.

 

8.
IDEMNIFICATION; REPRESENTATIONS AND WARRANTIES

 

8.1
Indemnification.

 

(a)
LICENSEE shall indemnify, defend and hold harmless LICENSOR and its directors, officers, medical and professional staff, employees,
independent contractors, and agents and their respective successors, heirs and assigns (each an “Indemnitee” under
this Section 8.1(a)), against any liability, damage, loss or expense (including reasonable attorney’s fees and expenses
of litigation) (collectively, “Losses”) incurred by or imposed upon such Indemnitees or any one of them in connection
with any claims, suits, actions, demands or judgments arising out of any theory of product liability (including, but not limited
to, actions in the form of tort, warranty, or strict liability) concerning any Licensed Product made, used or sold pursuant to
any right or license granted under this Agreement other than Losses arising out of claims of infringement of intellectual property
rights held by third parties by the practice of the Licensed Inventions, the existence of which rights constitute a breach of
the representations and warranties given by LICENSOR under Section 8.2(b) or (c).

 

(b)
LICENSOR shall indemnify, defend and hold harmless LICENSEE and its directors, officers, medical and professional staff, employees,
independent contractors, and agents and their respective successors, heirs and assigns (each an “Indemnitee” under
this Section 8.1(b)), against Losses incurred by or imposed upon such Indemnitees or any one of them in connection with any claims,
suits, actions, demands or judgments arising out of any claims of infringement of intellectual property rights held by third parties
by the practice of the Licensed Inventions, the existence of which rights constitute a breach of the representations and warranties
given by LICENSOR under Section 8.2(b) or (c); provided that in no event shall Licensor’s liability for this indemnity and
defense obligation exceed in the aggregate the total amount of Consideration actually paid to Licensor under this Agreement.

 

    	CONFIDENTIAL	12	 

    	 

    

 

(c)
No Indemnitee under clause (a) or clause (b) of this Section 8.1 shall be entitled to any indemnification under such clause for
any Loss to the extent that such Loss is attributable to the negligent activities, reckless misconduct or intentional misconduct
of such Indemnitee.

 

(d)
Any Indemnitee under clause (a) or clause (b) of this Section 8.1 shall give the party from whom indemnification under such clause
is sought (the “Indemnitor”) prompt written notice of any Losses or discovery of fact upon which such Indemnitee intends
to base a request for indemnification under such clause, provided, however, that an Indemnitor’s obligations to such
Indemnitee under this Section 8.1 shall not be rendered inapplicable as a result of the failure by such Indemnitee to notify such
Indemnitor as required under this Section 8.1(d), unless such failure materially prejudices such Indemnitor’s ability to
take action with respect to any such Loss.

 

(e)
Each Indemnitor under this Section 8.1 agrees, at its own expense, to provide attorneys reasonably acceptable to an Indemnitee
under this Section 8.1 to defend against any actions brought or filed against such Indemnitee with respect to the subject of indemnity
contained herein, whether or not such actions are rightfully brought. Each Indemnitee under this Section 8.1 shall be entitled
to participate in, but not control, the defense of such action and to employ counsel of its own choice for such purpose; provided,
however, that such employment shall be at such Indemnitee’s own expense.

 

(f)
Each Indemnitor shall have the sole right to consent to the entry of any judgment, enter into any settlement or otherwise dispose
of any Loss, on such terms as such Indemnitor, in its sole discretion, shall deem appropriate.

 

8.2
Representations and Warranties.

 

Mutual
representations:

 

(a)
LICENSOR and LICENSEE represent and warrant to each other that: (i) it is duly organized and validly existing under the laws of
its jurisdiction of incorporation or formation, and has full corporate or other power and authority to enter into this Agreement
and to carry out the provisions hereof; (ii) it is duly authorized and has Board approval, in the case of LICENSEE and manager/member
approval in the case of LICENSOR, to execute and delivery this Agreement and to perform its obligations hereunder and thereunder,
and the person or persons executing this Agreement on its behalf has been duly authorized to do so by all requisite corporate/company
action; (iii) this Agreement is legally binding upon it, enforceable in accordance with its terms, and does not conflict with
any agreement, instrument or understanding, oral or written, to which it is a party or by which it may be bound, nor violate any
material law or regulations of any court, governmental body or administrative or other agency having jurisdiction over it; (iv)
neither it nor any of its Affiliates have been debarred or is subject to debarment and will not use in any capacity, in connection
with the services to be performed under this Agreement, and person who has been debarred pursuant to Section 306 of the United
States Food, Drug and Cosmetic Act or who is subject of conviction in such section..

 

    	CONFIDENTIAL	13	 

    	 

    

 

LICENSOR
represents to LICENSEE that:

 

(a)
To the best of LICENSOR’s actual knowledge with respect solely to its Licensed Technology, as of the Effective Date there
is no fact or circumstance that would prevent the use of the Licensed Technology to develop Licensed Products that could be Approved
by a Regulatory Authority.

 

(b)
LICENSOR is the sole and exclusive owner of all right, title and interest in and to the Patent Rights to the Licensed Patents
originally listed on Schedule 1.11 and such rights, and all other rights granted to LICENSEE under the License existing as of
the date hereof, are not subject to any encumbrance, lien or claim of ownership by any third party. LICENSOR has obtained all
necessary assignments and made all appropriate filings with respect thereto in order to secure its sole and exclusive ownership
rights in and to such Patent Rights, and all other rights granted to LICENSEE as of the date hereof. During the term of this Agreement,
LICENSOR shall not knowingly take any action that would encumber the rights granted to LICENSEE hereunder.

 

(c)
Except for the grant by LICENSOR to LICENSEE of the License and other rights in Article 2, which relate solely to the Licensed
Product, LICENSOR has not, directly or indirectly, expressly or by implication, by action or omission or otherwise (i) assigned,
transferred or conveyed any right, title or interest in or to the Patent Rights in the Licensed Patents and/or any other rights
granted to LICENSEE under the License, (ii) granted any license or other right, title or interest in or to the Patent Rights in
the Licensed Patents and/or any other rights granted to LICENSEE under the License, or (iii) agreed to or is otherwise bound by
any covenant not to sue for any infringement, misuse or otherwise with respect to the Patent Rights in the Licensed Patents and/or
any other rights granted to LICENSEE under the License.

 

(d)
To the best of LICENSOR’s knowledge, there is no actual or threatened infringement by a third party of the Patent Rights
in the Licensed Patents.

 

8.3
Limitation on Damages and Disclaimer. WITH THE EXCEPTION FOR INTENTIONAL MISCONDUCT OR GROSS NEGLIGENCE OF SUCH
PARTY, IN NO EVENT SHALL EITHER PARTY BE LIABLE FOR SPECIAL, INDIRECT, INCIDENTAL, COLLATERAL, EXEMPLARY, PUNITIVE, OR CONSEQUENTIAL
DAMAGES, INCLUDING LOSS OF INCOME, PROFIT OR SAVINGS, OF ANY PARTY, INCLUDING THIRD PARTIES, REGARDLESS OF THE FORM OF THE ACTION
OR THE THEORY OF RECOVERY, EVEN IF SUCH PARTY HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES.

 

OTHER
THAN WARRANTIES SET FORTH HEREIN, EACH PARTY MAKES NO WARRANTY, EXPRESS OR IMPLIED, INCLUDING, WITHOUT LIMITATION, ANY IMPLIED
WARRANTY OF MERCHANTABILITY OR ANY IMPLIED WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO ANY PATENT, TRADEMARK,
SOFTWARE, TRADE SECRET, TANGIBLE RESEARCH PROPERTY, INFORMATION OR DATA LICENSED OR OTHERWISE PROVIDED TO THE OTHER PARTY HEREUNDER
AND HEREBY DISCLAIMS THE SAME.

 

    	CONFIDENTIAL	14	 

    	 

    

 

8.4
Insurance. Licensee will maintain insurance in amounts and areas of coverage that are considered commercially reasonable
in this industry. The Licensee will obtain such insurance coverages and will provide each other with proof of such insurance coverage.

 

9.
TERMINATION

 

9.1
Upon Expiration of Patent Rights and Exclusive Marketing Rights.

 

(a)
Unless otherwise terminated as provided for in this Agreement, the License and other rights granted to LICENSEE in Article 2 will
continue on a country by country and Licensed Product by Licensed Product basis, and shall expire in each country for each Licensed
Product sold in that country when the manufacture, use, sale, import or offer for sale of such Licensed Product in said country
on the later to occur of (i) the expiration date of the last to expire of the Licensed Patents or when a competitor generic product
utilizing the Licensed Technology is marketed in the particular country in the Territory. In such an event, the License, with
respect to such country and such Licensed Product, will be automatically converted to a fully paid-up royalty–free perpetual
license that grants LICENSEE the same bundle of rights as the License, including all the rights under Section 2.1(b) to grant
sublicenses.

 

(b)
Notwithstanding the foregoing, in the event LICENSOR and/or LICENSEE are unable to obtain patent protection for a Licensed Product
in any particular country, the License shall be in effect with respect to such Licensed Product in such country, with LICENSEE
paying LICENSOR fees equal to the normal royalty rates and subject to the conditions specified in Section 5.1, for a period of
ten (10) years after the First Commercial Sale of said Licensed Product in such country, so long as generic competition (where
“generic competition” exists when a product having the same active pharmaceutical ingredient as a Licensed Product,
and utilizing the Licensed Technology, is marketed by a competitor in the same country as said Licensed Product) is absent with
regard to said Licensed Product, as consideration for the right to use the Licensed Know How and the unpatented Licensed technology
as well as any continuing technical and informational marketing support from LICENSOR. At the earlier of the expiration of the
ten (10) year period or when generic competition begins with regard to said Licensed Product in a country for which there is no
Licensed Patent, the License, with respect to such country and Licensed Product, will convert to the fully paid-up royalty-free
perpetual license described in Section 9.1(a), including all the rights under Section 2.1(b) to grant sublicenses.

 

(c)
If LICENSEE was able to operate for some period under the protections of patent rights with regard to a particular Licensed Product
in a particular country, then, for so long as generic competition is absent with regards to said Licensed Product in said particular
country and upon the expiration of such patent rights and/or exclusive marketing rights, as described in Section 9.1(a), LICENSEE
shall continue to pay LICENSOR fees equal to the normal royalty rates and subject to the conditions specified in Section 5.1 for
the right to use the Licensed Know How and the unpatented Licensed Technology as well as any continuing technical and informational
marketing support from LICENSOR.

9.2
Upon Default, Generally. If either party shall fail to faithfully perform any of its obligations under this Agreement,
the non-defaulting party may give written notice of the default to the defaulting party. Unless such default is corrected within
sixty (60) days after such notice, the notifying party may terminate this Agreement upon thirty (30) days prior written notice;
provided, however, in the event that prior to the expiration of any such sixty (60) day period, such breaching party has
in good faith commenced to use commercially reasonable efforts to remedy such breach and the completion of such remedy, due to
reasons beyond the control of such breaching party, requires more than sixty (60) days to complete, then such sixty (60) day period
shall be extended for so long as such breaching party is continuing in good faith to use commercially reasonable efforts to remedy
such breach.

 

    	CONFIDENTIAL	15	 

    	 

    

 

9.3
If Commercially Unfeasible. LICENSEE may terminate this Agreement on thirty (30) days written notice to Licensor,
without penalty and at any time, if LICENSEE, at its sole discretion, determines that further development, manufacture, and/or
sales of the Licensed Products will be commercially unfeasible.

 

9.4
Effect on Sublicenses. In the event that the License granted to LICENSEE under this Agreement is terminated, any
sublicense under such License granted prior to termination of said License shall remain in full force and effect, provided that:

 

(a)
the Sublicensee is not then in breach of its sublicense agreement;

 

(b)
the Sublicensee agrees to be bound to LICENSOR as the licensor under the terms and conditions of this Agreement, as modified by
the provisions of this Section 9.4;

 

(c)
LICENSOR shall have the right to receive any payments payable to LICENSEE under such sublicense agreement to the extent that they
are reasonably and equitably attributable to such Sublicensee’s right under such sublicense to use and exploit Patent Rights
in the Licensed Patents and other rights granted in the License;

 

(d)
the Sublicensee agrees to be bound by the development and commercialization obligations of LICENSEE pursuant to Article 3 (whether
set by the parties or by arbitration) in the field and territory of the sublicense;

 

(e)
LICENSOR has the right to terminate such sublicense upon thirty (30) days prior written notice to LICENSEE and such Sublicensee
in the event of any material breach of the obligation to make the payments described in clause (c) of this Section 9.3, unless
such breach is cured prior to the expiration of such thirty (30) day period, and shall further have the right to terminate such
sublicense in the event of Sublicensee’s failure to meet its development obligations pursuant to clause (d) hereof; and

 

(f)
LICENSOR shall not assume, and shall not be responsible to each Sublicensee for, any representations, warranties or obligations
of LICENSEE to such Sublicensee, other than to permit such Sublicensee to exercise any rights to the Patent Rights in the Licensed
Patents and other rights under the License that are granted under such sublicense agreement consistent with the terms of this
Agreement.

 

9.5
Payments. Upon termination of the License granted hereunder, LICENSEE shall pay LICENSOR all royalties, milestone
payments and any other amounts due or accrued up to and including the date of termination and (ii) for twelve (12) months following
the date of termination, the sale of Licensed Products manufactured prior to the termination date, if LICENSEE and LICENSOR separately
agree to conduct such sales.

 

    	CONFIDENTIAL	16	 

    	 

    

 

10.
CONFIDENTIAL INFORMATION

 

10.1
Definitions. Each party receiving information (the “Receiving Party”) disclosed to it by the other party
(the “Disclosing Party”) acknowledges that by reason of its relationship to the Disclosing Party hereunder, between
the parties, will have, or has had, access to certain information and materials, including the terms of this Agreement and information
concerning the Disclosing Party’s business, plans, technology, products and/or services that are confidential and of substantial
value to the Disclosing Party (“Confidential Information”).

 

10.2
Obligation to Protect Confidential Information. Each Receiving Party agrees that it shall (i) take every reasonable
precaution to protect the confidentiality of Disclosing Party’s Confidential Information from unauthorized access or use
and (ii) not use the Disclosing Party’s Confidential Information in any way for the Receiving Party’s own account
or the account of any third party except for the purposes of performing its obligations under this Agreement. Upon termination
of this Agreement and at the request of the Disclosing Party, the Receiving Party will return to Disclosing Party all of the Disclosing
Party’s Confidential Information in its possession or within its control or destroy such Confidential Information and certify
in writing to the Disclosing Party that all such information has been destroyed; however, Receiving Party shall have the right
to retain one (1) copy of the Disclosing Party’s Confidential Information solely for the purpose of determining Receiving
Party’s obligations under this Agreement.

 

10.3
Exclusions. Confidential Information does not include any information that the Receiving Party can demonstrate by
written records: (a) was known to the Receiving Party prior to its disclosure by the Disclosing Party; (b) was independently developed
by the Receiving Party without use of or reference to the Disclosing Party’s Confidential Information; (c) was or becomes
publicly known through no wrongful act of the Receiving Party; (d) was rightfully received from a third party whom the Receiving
Party had reasonable grounds to believe was authorized to make such disclosure without restriction; or (e) has been approved for
public release by the Disclosing Party’s prior written authorization. Further, if the Receiving Party is required to disclose
Confidential Information pursuant to a subpoena, court order or other similar process (“Court Order”), it is agreed
that the Receiving Party shall provide the Disclosing Party with notice of such request(s), to the extent that such notice is
legally permissible, so that the Disclosing Party may seek an appropriate protective order. In the event that the Disclosing Party
is not successful in obtaining a protective order and the Receiving Party is compelled to disclose the Confidential Information,
the Receiving Party may disclose such information solely in accordance with and for the limited purpose of compliance with the
Court Order without liability hereunder.

 

10.4
Disclosures Required by Law. In addition, either party may disclose, on a confidential basis, the existence and
terms of this Agreement to existing or potential investors in such party, or in connection with a private or public offering of
such party’s securities. Furthermore, either party may disclose, on a confidential and need-to-know basis, the existence
and terms of this Agreement and the proposed terms of this Agreement to its counsel, accountants, directors and other similar
advisors (the “Representatives”). The foregoing shall not, however, operate or grant either party any rights under
any patents, trade secrets, copyrights, or any other proprietary rights of the other party.

 

    	CONFIDENTIAL	17	 

    	 

    

 

10.5
Remedies. The parties acknowledge that money damages would be both incalculable and an insufficient remedy for any
breach of the confidentiality provisions of this Agreement, and that any such breach would cause the other party irreparable harm.
Accordingly, the parties hereto agree that in the event of any such breach or threatened breach hereof by a party or by its respective
Representatives, the other party to this Agreement shall be entitled, in addition to any other available remedies at law, to seek
equitable relief, including injunctive relief and specific performance without the posting of any bond or other security.

 

11.
MISCELLANEOUS

 

11.1
Entire Agreement. This Agreement constitutes the entire understanding between the parties with respect to the subject
matter hereof.

 

11.2
Notices. All notices and other communications required or permitted under this Agreement shall be in writing and
shall be sent by registered or certified mail (return receipt requested and postage prepaid), or delivered by hand, by messenger
or by a recognized overnight delivery service, addressed to each party as follows:

 

if
to LICENSOR:

 

KOTZKER
CONSULTING LLC

20
Highview Ln.

Yardley,
PA 19067

Attn:
Joseph Morgan, M.D.

 

With
a copy to:

 

Gerard
P. Norton

Fox
Rothschild LLP

997
Lenox Drive, Building 3

Lawrenceville,
NJ

08543

 

if
to LICENSEE:

 

INTIVA
KOTZKER PHARMACEUTICALS INC.

3773
Cherry Creek North Drive

Suite
575

Denver
Colorado 80209

Attn:
Jeffery Friedland

 

    	CONFIDENTIAL	18	 

    	 

    

 

With
a copy to:

 

Robert
I. Goldfarb

Robert
I. Goldfarb P.A.

6100
Hollywood Blvd, Suite 207

Hollywood,
FL 33024

 

Each
such notice or other communication shall for all purposes of this Agreement be treated as effective or having been given (i) if
sent by registered or certified mail, the earlier of receipt and five (5) business days after dispatch, and (ii) if delivered
in person, by messenger, or by overnight courier, on the business day delivered.

 

11.3
Amendments; Waivers. This Agreement may be amended or any of its terms or conditions may be waived only by a written
instrument executed by the parties or, in the case of a waiver, by the party waiving compliance. The failure of either party at
any time or times to require performance of any provision hereof shall in no manner affect its rights at a later time to enforce
the same. No waiver by either party of any condition shall be deemed as a further or continuing waiver of such condition or term
or of any other condition or term.

 

11.4
Assignment, Successors. This Agreement shall be binding upon and inure to the benefit of and be enforceable by the
parties hereto and their respective successors and permitted assigns; provided that this Agreement shall not be assignable by
LICENSOR without LICENSEE’s written consent (which consent shall not be unreasonably withheld, delayed or conditioned) except
for the right to receive royalties or other payments payable herein, and further provided that LICENSEE may, with the consent
of LICENSOR (which consent shall not be unreasonably withheld, delayed or conditioned), transfer its interest or any part thereof
under this Agreement to a wholly-owned subsidiary of LICENSEE or to any assignee or purchaser of the portion of its business associated
with the manufacture and sale of Licensed Product, so long as such transferee assumes and agrees to be bound by the provisions
of this Agreement.

 

11.5
Force Majeure. Any delays in or failures of performance by either party under this Agreement shall not be considered
a breach of this Agreement if and to the extent caused by occurrences beyond the reasonable control of the party affected, including
but not limited to: acts of God, acts, regulations, or laws of any government, strikes or the concerted acts of workers, fires,
floods, explosions, riots, wars, rebellion, and sabotage. Any time for performance hereunder shall be extended by the actual time
of delay caused by such occurrence; provided, however, that either party shall have the right to terminate this Agreement
if any such extension endures for more than twelve (12) consecutive months.

 

11.6
Publicity. Neither party shall use the name of the other party or any staff member, officer, employee or student
of the other party or any adaptation thereof in any advertising, promotional or sales literature, publicity or in any document
employed to obtain funds or financing without the prior written approval of the party or individual whose name is to be used.
Notwithstanding the foregoing, the parties agree that LICENSEE may disclose to its Representatives, investors and potential investors
that Dr. Joseph Morgan is the physician and scientist who conceived of the concepts and is reflected as the inventor in the patent
applications.

 

    	CONFIDENTIAL	19	 

    	 

    

 

11.7
Governing Law. This Agreement shall be governed by and construed and interpreted in accordance with the laws of
the State of Colorado, without regard to its choice of law principles.

 

11.8
Alternative Dispute Resolution. For any and all claims, disputes, or controversies arising under, out of, or in
connection with this Agreement, except issues relating to the validity, construction or effect of any Patent Right, which the
parties shall be unable to resolve within sixty (60) days, then either party may after such sixty (60) day period advise the other
party of its intent to pursue such claim, dispute, or controversy in Alternative Dispute Resolution (ADR) in a writing which describes
in reasonable detail the nature of such dispute. By not later than five (5) business days after the recipient has received such
notice of dispute, each party shall have selected for itself a representative who shall have the authority to bind such party
and shall additionally have advised the other party in writing of the name and title of such representative. By not later than
ten (10) business days after the date of such notice of dispute, such representatives shall agree upon a third party, which is
in the business of providing Alternative Dispute Resolution (ADR) services (hereinafter, “ADR Provider”) and shall
schedule a date with such ADR Provider to engage in ADR. Thereafter, the representatives of the parties shall engage in good faith
in an ADR process under the auspices of the selected ADR Provider. If within the aforesaid ten (10) business days after the date
of the notice of dispute the representatives of the parties have not been able to agree upon an ADR Provider and schedule a date
to engage in ADR, or if they have not been able to resolve the dispute within thirty (30) business days after the conclusion of
ADR, the parties shall have the right to pursue any other remedies legally available to resolve such dispute in either the state
or federal courts of Colorado, to whose jurisdiction for such purposes each of LICENSOR and LICENSEE hereby irrevocably consents
and submits. Notwithstanding the foregoing, nothing in this Section 11.8 shall be construed to waive any rights or timely performance
of any obligations existing under this Agreement.

 

11.9
Severability. If any provision(s) of this Agreement are or become invalid, are ruled illegal by any court of competent
jurisdiction or are deemed unenforceable under then current applicable law from time to time in effect during the term thereof,
it is the intention of the parties that the remainder of this Agreement shall not be affected thereby. It is further the intention
of the parties that in lieu of each such provision which is invalid, illegal or unenforceable, there be substituted or added as
part of this Agreement a provision which shall be as similar as possible in economic and business objectives as intended by the
parties to such invalid, illegal or enforceable provision, but shall be valid, legal and enforceable.

 

11.10
Independent Contractors. It is expressly agreed that LICENSOR, on the one hand, and LICENSEE, on the other hand,
shall be independent contractors and that the relationship between the two parties shall not constitute a partnership, joint venture
or agency. Neither LICENSOR, on the one hand, nor LICENSEE, on the other hand, shall have the authority to make any statements,
representations or commitments of any kind, or to take any action, which shall be binding on the other, without the prior written
consent of the other party to do so. All persons employed by a party shall be employees of such party and not of the other party
and all costs and obligations incurred by reason of any such employment shall be for the account and expense of such party.

 

11.11
Survival. Sections 5, 6, 8, 9 10 and 11 shall survive the expiration or termination of this Agreement.

 

11.12
Counterparts. This Agreement may be executed in two counterparts, each of which shall be enforceable against the
party actually executing such counterpart, and both of which together shall constitute one instrument.

 

11.13
Titles and Subtitles. The titles and subtitles used in this Agreement are used for convenience only and are not
considered in construing or interpreting this Agreement.

 

THE
PARTIES have duly executed this Agreement as of the date first shown above written.

 

[signature
page follows]

 

    	CONFIDENTIAL	20	 

    	 

    

 

[signature
page to Exclusive License Agreement]

 

	LICENSOR:
    	 	LICENSEE:
	KOTZKER
    CONSULTING LLC	 	INTIVA
    KOTZKER PHARMACEUTICALS INC.
	 	           	 	 	                         
	BY:	 	 	BY:	 
	NAME:	 	 	NAME:	 
	TITLE:
    	 	 	TITLE:
    	 
	 	 	 	 	 
	 	 	 	 	 
	 	 	 	 	 
	 	 	 	 	 

 

    	CONFIDENTIAL	21	 

    	 

    

 

Schedule
1.11

 

Patents
and Patent Applications

 

	Country	 	Status	 	Application
    #	 	Filing
    Date	 	Publication
    #	 	Publication
    Date
	Canada	 	Pending	 	2,895,805	 	18-Jun-2015	 	 	 	 
	European Patent Office	 	Published	 	13866227.5	 	17-Jul-2015	 	2934512	 	28-Oct-2015
	Israel	 	Pending	 	238946	 	21-May-2015	 	 	 	 
	India	 	Pending	 	1877/KOLNP/2015	 	16-Jun-2015	 	 	 	 
	United States	 	Published	 	14/649,951	 	05-Jun-2015	 	2015-0313868	 	05-Nov-2015
	Untiled States	 	Expired	 	61/738,782	 	18-Dec-2012	 	 	 	 
	PCT	 	Expired	 	PCT/US13/76223	 	18-Dec-2013	 	2014/100231	 	26-Jun-2014

 

    	CONFIDENTIAL	22EXCLUSIVE
LICENSE AGREEMENT

 

THIS
EXCLUSIVE LICENSE AGREEMENT (the “Agreement”), effective as of this 28th day of February, 2018, between ACCU-BREAK
PHARMACEUTICALS, INC., a Florida corporation having a business address of 6100 Hollywood Boulevard, Suite 207, Hollywood,
FL 33024 (the “Licensor”) and INTIVA BIOPHARMA INC., a Delaware corporation having a business address at 4340
East Kentucky Avenue, Suite 206, Denver, CO 80246 (the “Licensee”).

 

RECITALS

 

WHEREAS,
Licensor owns all right, title and interest in certain Licensed Technology (as hereinafter defined), for use with Cannabinoids
(as hereinafter defined) in recreational, Medicinal and Pharmaceutical (as both terms are hereinafter defined) products for the
treatment of various medical conditions and disorders for humans and animals; and

 

WHEREAS,
Licensee desires to license Licensor’s right, title and interest in the Licensed Technology in the Licensed Field and in
the Territory (as hereinafter defined), and Licensee desires to secure such license in order to develop, commercialize, sell,
and license throughout the Territory products that embody or employ the Licensed Technology;

 

NOW
THEREFORE, in consideration of the premises, and the receipt of good and valuable consideration the sufficiency of which is hereby
acknowledged, the parties hereto agree as follows:

 

1.
DEFINITIONS

 

1.1
“Accounting Period” shall mean each three-month period ending March 31, June 30, September 30, and December
31 during the term of this Agreement.

 

1.2
“Affiliate” with respect to each party shall mean any corporation or other legal entity controlling, controlled
by, or under common control with such party. The term “control” means possession, direct or indirect, of the powers
to direct or cause the direction of the management and policies of an entity, whether through the ownership of voting securities,
by contract or otherwise.

 

1.3
“API” means active pharmaceutical ingredient.

 

1.4
“Cannabinoids” means any of the chemical compounds that
are the active components of the Cannabis genus of plants and its three species, Cannabis sativa, Cannabis indica, and Cannabis
ruderalis; whether the compounds are synthetically produced or plant-derived, as well as cannabinoid compounds, formulations
or products, that include single and/or multiple Cannabinoids including both synthetic and plant-derived Cannabinoids, as well
as any and all Cannabinoid analogues. For formulations or compounds which may include combinations of API’s, other than
Cannabinoids or terpenes, it is being agreed that if the API is another FDA approved Pharmaceutical, Licensor approval will be
required to ensure that the API is not the subject of a current Licensor product, or the product of another licensee of the Licensor.

 

    	CONFIDENTIAL	1	 

    	 

    

 

1.5
“Effective Date” shall mean the date first written above.

 

1.6
“FDA” shall mean the United States Food and Drug Administration and any successor thereto.

 

1.7
“First Commercial Sale” shall mean the first sale of any Licensed Product by Licensee, its Affiliates or Sublicensees,
but not including transfers or dispositions of Licensed Product for charitable, promotional, pre-clinical, clinical, regulatory
or governmental purposes for which Licensee receives no payment.

 

1.8
“GMP” means good manufacturing practices required in order to conform
to the guidelines recommended by agencies that control the authorization and licensing of the manufacture and sale of food and
beverages, cosmetics, Pharmaceutical products, dietary supplements, and medical devices.

 

1.9
“License” shall have the meaning ascribed to that term in Section 2.1(a).

 

1.10
“License Fee” shall have the meaning ascribed to that term in Section 5.1(a).

 

1.11
“Licensed Field” shall mean the use of Cannabinoids, together with the Licensed Technology for recreational,
Medicinal and Pharmaceutical purposes in humans and animals.

 

1.12
“Licensed Inventions” shall mean the inventions claimed in the Licensed Patents.

 

1.13
“Licensed Know-how” shall include all technology, materials, research data, designs, formulas, process information,
manufacturing information, application information, commercialization information, clinical data, scientific data, medical data,
and any other information useful from time to time for the design, development, manufacturing, use, and/or commercialization of
the Licensed Products, whether or not eligible for protection under the patent laws of the United States or elsewhere and whether
or not any such technology, materials, information, data and the like related thereto, would be enforceable as a trade secret
or the copying of which would be enjoined or restrained by a court as constituting unfair competition, which is developed by,
or in the possession or control of, Licensor now or at any time during the term of this Agreement other than such information
that is independently developed by Licensee or its agents, as evidenced by contemporaneous written records.

 

1.14
“Licensed Patents” shall mean any and all rights arising out of or resulting from (i) the patents and patent
application set forth in Schedule 1.14 attached to this Agreement, as well as any additional patents or patent applications related
to any aspect of any Licensed Technology Improvements, Licensed Know-how, Licensed Products, and/or Licensed Technology (as herein
defined) filed prior to or during the term of this Agreement and (ii) any patent granted in respect of all such applications,
as well as, without limitation, any substitutions, divisions, continuations, continuations-in-part, reissues, renewals, re-examinations,
extensions, supplementary protection certificates, confirmations, registrations, revalidations and the like, of any and all such
patents and patent applications and any international equivalents thereof.

 

    	CONFIDENTIAL	2	 

    	 

    

 

1.15
“Licensed Products” shall mean any and all products comprising tablets with Cannabinoids) utilizing the Licensed
Technology for the delivery of a recreational, Medicinal or Pharmaceutical Cannabinoids product in specific dosage forms.

 

1.16
“Licensed Technology” shall mean the aggregate of the Licensed Inventions, the Licensed Know-how, the Licensed
Products and the Licensed Patents and any other information and/or technology related to the Licensed Products and/or the design
and/or the manufacturing of the Licensed Products.

 

1.17
“Licensed Technology Improvements” shall have the meaning ascribed to that term in Section 2.2.

 

1.18
“Medicinal” shall mean any product containing marijuana, hemp or cannabis produced
and sold for health, wellness, or nutritional purposes, including as herbal medicine, including products produced or sold through
U.S. state-licensed or regulated marijuana programs and comparable programs in other countries and jurisdictions. 

 

1.19
“Milestone Payments” shall have the meaning ascribed to that term in Section 5.1(b).

 

1.20
(a) “Net Sales” shall mean the Gross Sales (as defined and calculated in accordance with US generally accepted
accounting principles (“GAAP”)) of Licensed Products by Licensee or any of its Affiliates or Sublicensees (“Sellers”)
to a third party that is not an Affiliate or Sublicensee of Licensee (“Customer”), less applicable Sales Returns and
Allowances (as defined below), and corresponding to the definition of actual net sales used in the audited consolidated financial
statements of Licensee:

 

“Sales
Returns and Allowances” means the sum of

 

	 	(a)	(i)
    as determined under US GAAP, trade, cash, and quantity discounts or rebates (other than price discounts granted at the time
    of invoicing and which are included in the determination of Gross Sales), credits or allowances given or made for rejection
    or return of, and for uncollectible amounts on, previously sold Licensed Products or for retroactive price reductions (including
    any types of rebates and charge-backs), (ii) taxes, duties, or other governmental charges levied on or measured by the billing
    amount for Licensed Products, and (iii) credits for allowances given or made for wastage, replacement, indigent patient, and
    any other sales programs for Licensed Products; and 
	 	(b)	periodic
    adjustments of the amount determined in (a) to reflect amounts actually incurred by Licensee for items (i), (ii), and (iii)
    in clause (a). 

 

(b)
For purposes of determining Gross Sales, a “sale” shall not include transfers or dispositions for charitable, promotional
purposes or for pre-clinical, clinical, regulatory or governmental testing purposes for which a Seller receives no payment.

 

    	CONFIDENTIAL	3	 

    	 

    

 

(c)
If a Seller commercially uses or disposes of any Licensed Product by itself (as opposed to use or disposition of the Licensed
Product as a component of a combination of active functional elements) other than in a bona fide sale to a bona fide Customer,
the Gross Sales price of the Licensed Product for purposed of calculating Gross Sales shall be the price which would be then payable
in an arm’s length transaction with such a Customer.

 

(d)
Transfer of a Licensed Product within a Seller or between or among Licensee and its Affiliate and Sublicensees for sale by the
transferee shall not be considered a sale, commercial use or disposition for the purpose of the foregoing subsections; in the
case of such transfer the Gross Sales price shall be the Gross Sales price of the Licensed Product when sold to a third party
by the transferee.

 

1.21
“Patent Right” shall mean any right, title or interest in any Licensed Patent.

 

1.22
“Pharmaceutical” means relating to drugs and subject to a variety of
laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs under the rules and regulations
of the FDA or similar international agencies

 

1.23
“Regulatory Authorities” shall mean the governmental authorities responsible for regulating the development,
marketing, and/or sales of Pharmaceutical products in a particular country.

 

1.24
“Seller” shall mean with respect to any sale of a Licensed Product the party responsible for such sale, where
such party may be, as applicable, Licensee, an Affiliate of Licensee or a Sublicensee.

 

1.25
“Sublicensee” shall mean any third party licensed by Licensee or by an Affiliate thereof to develop or have
developed, make or have made, use or have used, sell or have sold, import or have imported any Licensed Product. For the avoidance
of doubt, a wholesaler, distributor, or similar entity which purchases any Licensed Product from Licensee or any of its Affiliates,
shall not be deemed to be a Sublicensee.

 

1.26
“Sublicensee Payments” shall have the meaning ascribed to that term in Section 5.2(ii).

 

1.27
“Term” shall mean the period during which this Agreement is in effect, commencing on the Effective Date and
continuing until the termination of the Agreement.

 

1.28
“Territory” shall mean the World.

 

1.29
“Valid Claim” shall mean any pending or issued claim of any patent application or patent that has not been
finally rejected or declared invalid or unenforceable by a patent office or court of competent jurisdiction in any unappealed
and unappealable decision.

 

    	CONFIDENTIAL	4	 

    	 

    

 

2.
LICENSE

 

2.1
Grant of License. Subject to the provisions of this Agreement, Licensor hereby grants Licensee, including Licensee’s
Affiliates,

 

(a)
during the Term, a royalty-bearing, Territory-wide license (the “License”) in the Licensed Field under the Patent
Rights to the Licensed Technology, as well as under the Licensed Patents, the Licensed Know-how, and the Licensed Technology,
regardless of whether such Licensed Patents are actually granted, to use the Licensed Know-how and Licensed Technology and to
develop and have developed, make and have made, use and have used, sell and have sold, offer for sale and have offered for sale,
import and have imported, export and have exported, any and all inventions claimed in the Licensed Patents related to the Licensed
Products and/or any compounds, chemicals, substrates, devices, tools, dies, molds or any other materials whatsoever that are useful
in the development and/or manufacturing and/or sale of the Licensed Products, and particularly including, without limitation,
such license to develop and have developed, make and have made, use and have used, sell and have sold, offer for sale and have
offered for sale, import and have imported, export and have exported Licensed Products, which license shall be exclusive even
as to Licensor, and

 

(b)
the right to grant bona fide sublicenses to third parties, to develop and have developed, to make and have made, use and have
used, sell and have sold, import and have imported, export and have exported, Licensed Products, and to exercise all other rights
under the License; provided, however, Licensee shall not have the right to grant any sublicense or to transfer any of its
rights under the License unless each such sublicense or other transfer granted by Licensee contains terms and conditions under
which the Sublicensee or transferee will be bound in the same manner as Licensee is under this Agreement. A copy of the proposed
agreement shall be provided to Licensor prior to the execution of the Agreement.

 

2.2
Improvements. The parties acknowledge and agree that this Agreement shall apply to any and all improvements, modifications,
enhancements, or other changes to the Licensed Technology created, conceived, developed, or reduced to practice by Licensor during
the Term of this Agreement within the Licensed Field (collectively, the “Licensed Technology Improvements”). Licensed
Technology Improvements within the Licensed Field shall be considered to be a part of the Licensed Technology and shall be licensed
to Licensee in accordance with the provisions of this Agreement.

 

3.
DEVELOPMENT OBLIGATIONS

 

3.1
Licensee’s Obligations. Licensee shall use its commercially reasonable efforts to develop and commercialize
one or more Licensed Products, and, in particular, Licensee will be responsible for the (i) development and manufacture of recreation
and medicinal License Products and (ii) design, development, manufacturing, preclinical, clinical, and regulatory development
activities of Pharmaceutical Licensed Products in the Territory and shall bear the costs of such activities. Licensee shall be
responsible for the GMP manufacturing of the Licensed Products, where applicable, including the development of associated compounds,
chemicals, substrates, devices, tools, dies, molds, and or related materials.

 

    	CONFIDENTIAL	5	 

    	 

    

 

3.2
Progress Reports. At intervals no longer than every six (6) months, Licensee shall communicate with Licensor by
telephone or through in-person meetings on progress made toward achieving the development and commercialization of one or more
Licensed Products.

 

3.3
Cooperation of Licensor. Licensor, in consideration of the various continuing payment obligations of Licensee under
Article 5 (License Fees, Milestone Payments and Royalties) and Article 9 (Termination), shall provide to Licensee such assistance,
consultation and cooperation as shall be reasonably requested by Licensee relating to the development and commercialization of
Licensed Products. Licensee shall, as it deems necessary, separately contract with Licensor for consulting services regarding
the design and/or manufacturing of the Licensed Products. Licensor shall make available its personnel to provide such consulting
services at commercially reasonable consulting rates, and in accordance with other terms to be separately negotiated between Licensor
and Licensee. No compensation shall be paid to Licensor for any disclosures required under this Agreement.

 

3.4
Provision of Product in Support of Development and Sales. Licensee will manufacture or will have manufactured the
finished and packaged Licensed Products in support of development activities and for commercial sales.

 

4.
FILING, PROSECUTION AND MAINTENANCE OF LICENSED PATENTS

 

4.1
Responsibility. Licensor, at its expense, shall be responsible, and shall have sole decision-making authority, for
the preparation, filing, prosecution and maintenance of all existing patent applications and patents included in the Licensed
Patents. Additionally, Licensee, at its expense, shall be responsible and shall work together with Licensor with respect to the
preparation, filing and prosecution of any new patent applications using the Licensed Technology with the Licensed Products.

 

4.2
Delivery of Existing Documents. With respect to each Licensed Patent, each document or a draft thereof pertaining
to the filing, prosecution, or maintenance of such Licensed Patent, including, without limitation, each patent application, office
action, response to office action, request for terminal disclaimer, request for reissue or reexamination of any patent issuing
from such application, and all other prosecution items contained in the file maintained by or for Licensor in respect of such
Licensed Patent in the possession of Licensor or its counsel at the Effective Date shall be provided to Licensee within thirty
(30) days of the Effective Date and any such documents received by Licensor or its counsel from any patent office after the Effective
Date shall be provided within fifteen (15) days after receipt.

 

    	CONFIDENTIAL	6	 

    	 

    

 

5.
LICENSE FEES, MILESTONE PAYMENTS AND ROYALTIES

 

5.1
License Fees and Milestone Payments.

 

(a)
Licensee shall pay Licensor a License fee in the total amount of $100,000 (the “License Fee”), which License Fee shall
be payable as follows:

 

	 	●
    	The
    amount of $35,000 in the form of cash for access to the Licensed Technology will be paid by Licensee to Licensor upon the
    date of execution of this Agreement; 
	 	●	The
    amount of $30,000 in the form of cash shall be due within one hundred eighty (180) days from the date of execution of this
    Agreement; and
	 	●	The
    amount of $35,000 in the form of cash or (at the option of Licensee) common stock of Licensee, shall be due within one (1)
    year from the date of execution of this Agreement. 

 

(b)
With respect specifically to Pharmaceutical Licensed Products, milestone payments (the “Milestone Payments”) may be
paid in cash or (at the option of Licensee) common stock of Licensee pursuant to the following:

 

	 	●	A
    milestone payment of $100,000 shall be due upon approval of filing by each Regulatory Authority of each Pharmaceutical Licensed
    Product; 
	 	 	 
	 	●	A
    milestone payment of $100,000 shall be due upon approval by each Regulatory Authority of each Pharmaceutical Licensed Product;
    
	 	 	 
	 	●	A
    milestone payment of $50,000 shall be due upon achievement of $10,000,000 of cumulative Net Sales for any and all of the Licensed
    Products (for clarity purposes, this payment is a one-time only payment) in the Territory;
	 	 	 
	 	●	A
    milestone payment of $50,000 shall be due upon achievement of $25,000,000 of cumulative Net Sales for any and all of the Licensed
    Products (for clarity purposes, this payment is a one-time only payment) in the Territory;
	 	 	 
	 	●	A
    milestone payment of $50,000 shall be due upon achievement of $50,000,000 of cumulative Net Sales for any and all of the Licensed
    Products (for clarity purposes, this payment is a one-time only payment) in the Territory.

 

(c)
For the purposes of this Section 5.1, if License Fees and/or Milestone Payments are paid with common stock of Licensee, the shares
shall not be registered under federal securities laws and shall be valued using the weighted average over the five (5) trading
days immediately preceding the due date of the payment.

 

5.2
Royalties. Beginning with the First Commercial Sale in any country of any Licensed Product by Licensee or any of
its Affiliates or Sublicensees, Licensee shall pay to Licensor royalties in accordance with the following schedule for Licensed
Products sold by Licensee or its Affiliates and Sublicensees so long as the manufacture, use, sale, import or offer for sale of
such Licensed Product would, in the country where such manufacture, use, sale, import or offer for sale of such Licensed Product
occurs, infringe a Valid Claim of any Licensed Patent or violate an exclusive marketing right granted by any governmental agency
in such country in the absence of the License granted by Article 2 or a sublicense granted under Article 2:

 

    	CONFIDENTIAL	7	 

    	 

    

 

	 	(i)	 For
    sales of Licensed Products by Licensee and/or any Affiliate, four percent (4%) of the annual Net Sales thereof. 
	 	 	 
	 	(ii)	 For
    sales of Licensed Products by Sublicensees, twenty-five percent (25%) of the total revenue received by Licensee, or any Affiliate
    of Licensee, from any other person or organization in the form of royalties, milestone payments or any other consideration
    (including the proportionate share of such non-cash consideration, for example and without limitation, stock, real property,
    and ownership interests) in respect of sublicense(s) granted by Licensee or any of its Affiliates under Article 2 (“Sublicensee
    Payments”); 
	 	 	 
	 	(iii)	 Notwithstanding
    the foregoing (i) and (ii), the License Fee and Milestone Payments shall be offset against any amounts due to Licensor for
    royalties and Sublicensee Payments and only after the License Fee and Milestone Payments have been reimbursed in full to Licensee
    shall Licensor be entitled to a royalty payment or Sublicensee Payments. In other words, the License Fee and Milestone Payments
    shall be treated as a credit against Licensee’s obligations under this Section 5.2. For purposes of illustration, if
    Licensee has paid Licensor $100,000 in License Fees and Licensee has begun selling a recreational Licensed Product, Licensor
    shall not receive any royalty on the Net Sales of that recreational Licensed Product until the cumulative Net Sales for that
    Licensed Product equals Two Million Five Hundred Thousand Dollars ($2,500,000 multiplied by 4%, which equals $100,000). 
	 	 	 
	 	(iii)	  Development
    funds received by the Licensee and/or any Affiliate, from a Sublicensee or any other source, will not be considered revenue
    under Section 5.2(iii) and such funds shall not be subject to any royalty payment whatsoever to Licensor.

 

5.3
Overdue Payments. The payments due under this Agreement shall, if overdue, bear interest until payment at a per
annum rate equal to the lesser of ten percent (10%) and the maximum permitted by law. The payment of such interest shall not preclude
Licensor from exercising any other rights it may have as a consequence of the lateness of any payment.

 

5.4
Currency. All License Fees, Milestone Payments and royalty payments under this Agreement shall be in United States
Dollars. Whenever conversion from any foreign currency shall be required, such conversion shall be at the rate of exchange thereafter
published in the Wall Street Journal for the business day closest to the due date of the payment.

 

    	CONFIDENTIAL	8	 

    	 

    

 

6.
REPORTS AND PAYMENTS

 

6.1
Books of Accounts. Licensee shall keep, and shall cause each of its Affiliates and Sublicensees, if any, to keep
full and accurate books of accounts containing all particulars that may be necessary for the purpose of calculating all Milestone
Payments and royalties payable to Licensor. Such books of account shall be kept at their principal place of business and, with
necessary supporting data shall, during all reasonable times for the three (3) years next following the end of the calendar year
to which each shall pertain, be open for inspection at reasonable times by Licensor or its designee at Licensor’s expense
for the purpose of verifying royalty statements or compliance with this Agreement. In the event that any audit performed under
this Section 6.1 reveals an underpayment in excess of ten percent (10%) of the total amount determined by the auditor to be due
Licensor (the “Underpayment”), Licensee shall bear the full cost of such audit and shall remit any amounts due to
Licensor within ninety (90) days of receiving notice thereof from Licensor. Licensor shall have the right to audit yearly, provided
however if such audit reveals an Underpayment, Licensor shall thereafter have the right to audit on a semi-annual basis (with
the audit returning to a yearly basis after three (3) sequential semi-annual audits are conducted with no Underpayments discovered).

 

6.2
Quarterly Payments. In each year the amount of Milestone Payment and royalty due shall be calculated on a cash received
basis as of the end of each Accounting Period as defined in Section 1.1 of this Agreement and shall be paid within the sixty (60)
days next following such date, every such payment to be supported by the accounting prescribed in Section 6.3.

 

6.3
Accounting Reports. With each semiannual/quarterly payment, Licensee shall deliver to Licensor a full and accurate
accounting to include at least the following information:

 

(a)
Quantity of each Licensed Product sold by Licensee and its Affiliate or Sublicensees (by country);

 

(b)
Gross Sales billed and Net Sales received by Licensee or any of its Affiliates or Sublicensees (“Sellers”) for the
sale of each Licensed Product;

 

(c)
Quantities of each Licensed Product used by Licensee and its Affiliate or Sublicensees;

 

(d)
Names and addresses of all Sublicensees of Licensee; and

 

(e)
Total Milestone Payments and/or royalties payable to Licensor.

 

    	CONFIDENTIAL	9	 

    	 

    

 

7.
INFRINGEMENT 

 

7.1
Infringement of Licensed Patents. Each party shall promptly notify the other party of evidence of infringement of
a claim of a Licensed Patent by a third party. If either party shall have supplied the other party with written evidence demonstrating
prima facie infringement of a claim of a Licensed Patent in the Licensed Field by a third party, Licensee shall have the right
to take steps to protect the Patent Right in such claim, either upon notice from Licensor requesting such action, or on its own
initiative. Licensee shall notify Licensor, within three (3) months of one party providing the other with evidence of infringement,
whether Licensee intends to prosecute the alleged infringement. If Licensee notifies Licensor that it intends to so prosecute,
Licensee shall (at its expense), within three (3) months of its notice to Licensor either (i) cause infringement to terminate
or (ii) initiate and diligently prosecute legal proceedings against the infringer and in Licensor’s name if so required
by law. In the event Licensee notifies Licensor that Licensee does not intend to prosecute said infringement, Licensor may, upon
notice to Licensee, initiate legal proceedings against the infringer at Licensor’s expense. No settlement, consent judgment,
or other voluntary final disposition of the suit which invalidates or restricts the claims of such Patent Rights may be entered
into without the consent of the other party, which consent shall not be unreasonably withheld, but provided that, in the event
one party (“the Objecting Party”) withholds consent for a proposed settlement, the party proposing the settlement
may decline to support further costs of such suit or settlement discussions, and the Objecting Party shall be required to continue
such suit or settlement discussions at its own expense. Licensee shall indemnify Licensor against any order for payment that may
be made against Licensor in such proceedings brought by Licensee. Licensor shall indemnify Licensee against any claim of damages
that may be made against Licensee to the extent arising out of any proceedings which Licensor brings at its own expense pursuant
to Section 7.1 following Licensee’s decision not to prosecute any alleged infringement.

 

7.2
Cooperation. In the event one party shall initiate or carry on legal proceedings to enforce any Patent Right against
any alleged infringer, the other party shall fully cooperate with and supply all assistance reasonably requested by the party
initiating or carrying on such proceedings. The party which institutes any suit to protect or enforce a Patent Right shall have
sole control of that suit and shall bear the reasonable expenses (excluding legal fees) incurred by said other party in providing
such assistance and cooperating as is requested pursuant to this Section. The party initiating or carrying on such legal proceedings
shall keep the other party informed of the progress of such proceedings and said other party shall be entitled to counsel in such
proceedings but at its own expense. Any award paid by third parties as the result of such proceedings (whether by way of settlement
or otherwise) shall first be applied to reimbursement of the unreimbursed legal fees and expenses incurred by either party and
then the remainder shall be divided between the parties as follows:

 

(a)
If the amount is based on lost profits, Licensee shall receive an amount equal to the damages the court determines Licensee has
suffered as a result of the infringement less the amount of any royalties that would have been due Licensor on sales of Licensed
Product lost by Licensee as a result of the infringement had Licensee made such sales, and Licensor shall receive an amount equal
to the royalties it would have received if such sales had been made by Licensee, and

 

(b)
As to awards other than those based on lost profits, sixty percent (60%) to the party initiating such proceedings and forty percent
(40%) to the other party.

 

7.3
Infringement Actions by Third Parties. In the event that the making, selling or using of a Licensed Product in the
Licensed Field infringes the intellectual property rights of others, Licensee will have the first right to control any negotiation
or litigation with respect thereto; however, no settlement, consent judgment or other voluntary final disposition of the infringement
allegation may be entered into without the written consent, which shall not be unreasonably withheld, of Licensor.

 

    	CONFIDENTIAL	10	 

    	 

    

 

7.4
Further Assurances; Progress Reports. For the purpose of the proceedings referred to in this Article 7, Licensor
and Licensee shall permit the use of their names and shall execute such documents and carry out such other acts as may be necessary.
The party initiating or carrying on such legal proceedings shall keep the other party informed of the progress of such proceedings
and said other party shall be entitled to counsel in such proceedings but at its own expense, said expenses to be offset against
any damages received by the party bringing any infringement suit against a third party in accordance with Section 7.2.

 

8.
IDEMNIFICATION; REPRESENTATIONS AND WARRANTIES

 

8.1
Indemnification.

 

(a)
Licensee shall indemnify, defend and hold harmless Licensor and its directors, officers, medical and professional staff, employees,
independent contractors, and agents and their respective successors, heirs and assigns (each an “Indemnitee” under
this Section 8.1(a)), against any liability, damage, loss or expense (including reasonable attorney’s fees and expenses
of litigation) (collectively, “Losses”) incurred by or imposed upon such Indemnitees or any one of them in connection
with any claims, suits, actions, demands or judgments arising out of any theory of product liability (including, but not limited
to, actions in the form of tort, warranty, or strict liability) concerning any Licensed Product made, used or sold pursuant to
any right or license granted under this Agreement other than Losses arising out of claims of infringement of intellectual property
rights held by third parties by the practice of the Licensed Inventions, the existence of which rights constitute a breach of
the representations and warranties given by Licensor under Section 8.2(b) or (c).

 

(b)
Licensor shall indemnify, defend and hold harmless Licensee and its directors, officers, medical and professional staff, employees,
independent contractors, and agents and their respective successors, heirs and assigns (each an “Indemnitee” under
this Section 8.1(b)), against Losses incurred by or imposed upon such Indemnitees or any one of them in connection with any claims,
suits, actions, demands or judgments arising out of (i) any theory of product liability (including, but not limited to, actions
in the form of tort, warranty, or strict liability) concerning any Licensed Product made, used or sold by Licensee or any of its
Affiliates or Sublicensees pursuant to any right or license granted under this Agreement, but only to the extent that any such
claim, suit, action, demand or judgment owes to a failure on the part of Licensor to advise Licensee as to some unsafe element
of the Licensed Technology that was within Licensor’s actual knowledge (provided, however, that Licensor shall not have
any affirmative obligation to make a determination as to the safety of the Licensed Technology), (ii) any theory of product liability
(including, but not limited to, actions in the form of tort, warranty, or strict liability) concerning any Licensed Product made,
used or sold by Licensor or any of its Affiliates or Sublicensees and (iii) any claims of infringement of intellectual property
rights held by third parties by the practice of the Licensed Inventions, the existence of which rights constitute a breach of
the representations and warranties given by Licensor under Section 8.2(b) or (c).

 

    	CONFIDENTIAL	11	 

    	 

    

 

(c)
No Indemnitee under clause (a) or clause (b) of this Section 8.1 shall be entitled to any indemnification under such clause for
any Loss to the extent that such Loss is attributable to the negligent activities, reckless misconduct or intentional misconduct
of such Indemnitee.

 

(d)
Any Indemnitee under clause (a) or clause (b) of this Section 8.1 shall give the party from whom indemnification under such clause
is sought (the “Indemnitor”) prompt written notice of any Losses or discovery of fact upon which such Indemnitee intends
to base a request for indemnification under such clause, provided, however, that an Indemnitor’s obligations to such
Indemnitee under this Section 8.1 shall not be rendered inapplicable as a result of the failure by such Indemnitee to notify such
Indemnitor as required under this Section 8.1(d), unless such failure materially prejudices such Indemnitor’s ability to
take action with respect to any such Loss.

 

(e)
Each Indemnitor under this Section 8.1 agrees, at its own expense, to provide attorneys reasonably acceptable to an Indemnitee
under this Section 8.1 to defend against any actions brought or filed against such Indemnitee with respect to the subject of indemnity
contained herein, whether or not such actions are rightfully brought. Each Indemnitee under this Section 8.1 shall be entitled
to participate in, but not control, the defense of such action and to employ counsel of its own choice for such purpose; provided,
however, that such employment shall be at such Indemnitee’s own expense.

 

(f)
Each Indemnitor shall have the sole right to consent to the entry of any judgment, enter into any settlement or otherwise dispose
of any Loss, on such terms as such Indemnitor, in its sole discretion, shall deem appropriate.

 

8.2
Representations and Warranties.

 

Licensor
represents to Licensee that:

 

(a)
To the best of Licensor’s actual knowledge with respect solely to its Licensed Technology, there is no fact or circumstance
that could adversely affect the acceptance, or the subsequent approval, by any regulatory authority of any filing, application
or request with respect to the development or commercialization of any Licensed Product, existing on the Effective Date.

 

(b)
Licensor is the sole and exclusive owner of all right, title and interest in and to the Patent Rights to the Licensed Patents
originally listed on Schedule 1.14 and such rights, and all other rights granted to Licensee under the License existing as of
the date hereof, are not subject to any encumbrance, lien or claim of ownership by any third party. Licensor has obtained all
necessary assignments and made all appropriate filings with respect thereto in order to secure its sole and exclusive ownership
rights in and to such Patent Rights, and all other rights granted to Licensee as of the date hereof. During the term of this Agreement,
Licensor shall not knowingly take any action that would encumber the rights granted to Licensee hereunder.

 

    	CONFIDENTIAL	12	 

    	 

    

 

(c)
Except for the grant by Licensor to Licensee of the License and other rights in Article 2, which relate solely to the Licensed
Product, Licensor has not, directly or indirectly, expressly or by implication, by action or omission or otherwise (i) assigned,
transferred or conveyed any right, title or interest in or to the Patent Rights in the Licensed Patents and/or any other rights
granted to Licensee under the License, (ii) granted any license or other right, title or interest in or to the Patent Rights in
the Licensed Patents and/or any other rights granted to Licensee under the License, or (iii) agreed to or is otherwise bound by
any covenant not to sue for any infringement, misuse or otherwise with respect to the Patent Rights in the Licensed Patents and/or
any other rights granted to Licensee under the License.

 

(d)
To the best of Licensor’s knowledge, there is no actual or threatened infringement by a third party of the Patent Rights
in the Licensed Patents.

 

8.3
Limitation on Damages and Disclaimer. WITH THE EXCEPTION FOR INTENTIONAL MISCONDUCT OF SUCH PARTY, IN NO EVENT SHALL
EITHER PARTY BE LIABLE FOR SPECIAL, INDIRECT, INCIDENTAL, COLLATERAL, EXEMPLARY, PUNITIVE, OR CONSEQUENTIAL DAMAGES, INCLUDING
LOSS OF INCOME, PROFIT OR SAVINGS, OF ANY PARTY, INCLUDING THIRD PARTIES, REGARDLESS OF THE FORM OF THE ACTION OR THE THEORY OF
RECOVERY, EVEN IF SUCH PARTY HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES.

 

OTHER
THAN WARRANTIES SET FORTH HEREIN, EACH PARTY MAKES NO WARRANTY, EXPRESS OR IMPLIED, INCLUDING, WITHOUT LIMITATION, ANY IMPLIED
WARRANTY OF MERCHANTABILITY OR ANY IMPLIED WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO ANY PATENT, TRADEMARK,
SOFTWARE, TRADE SECRET, TANGIBLE RESEARCH PROPERTY, INFORMATION OR DATA LICENSED OR OTHERWISE PROVIDED TO THE OTHER PARTY HEREUNDER
AND HEREBY DISCLAIMS THE SAME.

 

8.4
Insurance. Each party will maintain insurance in amounts and areas of coverage that are considered commercially
reasonable in this industry.

 

9.
TERMINATION

 

9.1
Upon Expiration of Patent Rights and Exclusive Marketing Rights. Unless otherwise terminated as provided for in
this Agreement, the License and other rights granted to Licensee in Article 2 will continue on a country by country and Licensed
Product by Licensed Product basis, and shall expire in each country for each Licensed Product sold in that country when the manufacture,
use, sale, import or offer for sale of such Licensed Product would not, in said country, infringe a Valid Claim of any Licensed
Patent or violate an exclusive marketing right granted by any governmental agency in such country in the absence of the License
granted by Article 2 or a sublicense granted under Article 2. Upon such expiration, the License, with respect to such country
and such Licensed Product, will be automatically converted to a fully paid-up royalty–free perpetual license that grants
Licensee the same bundle of rights as the License, including all the rights under Section 2.1(b) to grant sublicenses.

 

    	CONFIDENTIAL	13	 

    	 

    

 

9.2
Upon Default, Generally. If either party shall fail to faithfully perform any of its obligations under this Agreement,
the non-defaulting party may give written notice of the default to the defaulting party. Unless such default is corrected within
sixty (60) days after such notice, the notifying party may terminate this Agreement upon thirty (30) days prior written notice;
provided, however, in the event that prior to the expiration of any such sixty (60) day period, such breaching party has
in good faith commenced to use commercially reasonable efforts to remedy such breach and the completion of such remedy, due to
reasons beyond the control of such breaching party, requires more than sixty (60) days to complete, then such sixty (60) day period
shall be extended for so long as such breaching party is continuing in good faith to use commercially reasonable efforts to remedy
such breach.

 

9.3
If Commercially Unfeasible. Licensee may terminate this Agreement, as to a particular Licensed Product, without
penalty and at any time, if Licensee, at its sole discretion, determines that further development, manufacture, and/or sales of
the Licensed Products will be commercially unfeasible.

 

9.4
Effect on Sublicenses. In the event that the License granted to Licensee under this Agreement is terminated, any
sublicense under such License granted prior to termination of said License shall remain in full force and effect, provided that

 

(a)
the Sublicensee is not then in breach of its sublicense agreement;

 

(b)
the Sublicensee agrees to be bound to Licensor as the licensor under the terms and conditions of this Agreement, as modified by
the provisions of this Section 9.4;

 

(c)
Licensor shall have the right to receive any payments payable to Licensee under such sublicense agreement to the extent that they
are reasonably and equitably attributable to such Sublicensee’s right under such sublicense to use and exploit Patent Rights
in the Licensed Patents and other rights granted in the License;

 

(d)
the Sublicensee agrees to be bound by the development and commercialization obligations of Licensee pursuant to Article 3 (whether
set by the parties or by arbitration) in the field and territory of the sublicense;

 

(e)
Licensor has the right to terminate such sublicense upon thirty (30) days prior written notice to Licensee and such Sublicensee
in the event of any material breach of the obligation to make the payments described in clause (c) of this Section 9.4, unless
such breach is cured prior to the expiration of such thirty (30) day period, and shall further have the right to terminate such
sublicense in the event of Sublicensee’s failure to meet its development obligations pursuant to clause (d) hereof; and

 

(f)
Licensor shall not assume, and shall not be responsible to each Sublicensee for, any representations, warranties or obligations
of Licensee to such Sublicensee, other than to permit such Sublicensee to exercise any rights to the Patent Rights in the Licensed
Patents and other rights under the License that are granted under such sublicense agreement consistent with the terms of this
Agreement.

 

    	CONFIDENTIAL	14	 

    	 

    

 

9.5
Payments. Upon termination of the License granted hereunder, Licensee shall pay Licensor all royalties due or accrued
on (i) the sale of Licensed Products up to and including the date of termination and (ii) for twelve (12) months following the
date of termination, the sale of Licensed Products manufactured prior to the termination date, if Licensee and Licensor separately
agree to conduct such sales.

 

10.
CONFIDENTIAL INFORMATION

 

10.1
Definitions. Each party receiving information (the “Receiving Party”) disclosed to it by the other party
(the “Disclosing Party”) acknowledges that by reason of its relationship to the Disclosing Party hereunder, between
the parties, will have, or has had, access to certain information and materials, including the terms of this Agreement and information
concerning the Disclosing Party’s business, plans, technology, products and/or services that are confidential and of substantial
value to the Disclosing Party (“Confidential Information”).

 

10.2
Obligation to Protect Confidential Information. Each Receiving Party agrees that it shall (i) take every reasonable
precaution to protect the confidentiality of Disclosing Party’s Confidential Information from unauthorized access or use
and (ii) not use the Disclosing Party’s Confidential Information in any way for the Receiving Party’s own account
or the account of any third party except for the purposes of performing its obligations under this Agreement. Upon termination
of this Agreement and at the request of the Disclosing Party, the Receiving Party will return to Disclosing Party all of the Disclosing
Party’s Confidential Information in its possession or within its control or destroy such Confidential Information and certify
in writing to the Disclosing Party that all such information has been destroyed; however, Receiving Party shall have the right
to retain one (1) copy of the Disclosing Party’s Confidential Information solely for the purpose of determining Receiving
Party’s obligations under this Agreement.

 

10.3
Exclusions. Confidential Information does not include any information that the Receiving Party can demonstrate by
written records: (a) was known to the Receiving Party prior to its disclosure by the Disclosing Party; (b) was independently developed
by the Receiving Party without use of or reference to the Disclosing Party’s Confidential Information; (c) was or becomes
publicly known through no wrongful act of the Receiving Party; (d) was rightfully received from a third party whom the Receiving
Party had reasonable grounds to believe was authorized to make such disclosure without restriction; or (e) has been approved for
public release by the Disclosing Party’s prior written authorization. Further, if the Receiving Party is required to disclose
Confidential Information pursuant to a subpoena, court order or other similar process (“Court Order”), it is agreed
that the Receiving Party shall provide the Disclosing Party with notice of such request(s), to the extent that such notice is
legally permissible, so that the Disclosing Party may seek an appropriate protective order. In the event that the Disclosing Party
is not successful in obtaining a protective order and the Receiving Party is compelled to disclose the Confidential Information,
the Receiving Party may disclose such information solely in accordance with and for the limited purpose of compliance with the
Court Order without liability hereunder.

 

    	CONFIDENTIAL	15	 

    	 

    

 

10.4
Disclosures Required by Law. In addition, either party may disclose, on a confidential basis, the existence and
terms of this Agreement to existing or potential investors in such party, in connection with a private or public offering of such
party’s securities, or if required by law. Furthermore, either party may disclose, on a confidential and need-to-know basis,
the existence and terms of this Agreement and the proposed terms of this Agreement to its counsel, accountants, directors and
other similar advisors (the “Representatives”). The foregoing shall not, however, operate or grant either party any
rights under any patents, trade secrets, copyrights, or any other proprietary rights of the other party.

 

10.5
Remedies. The parties acknowledge that money damages would be both incalculable and an insufficient remedy for any
breach of the confidentiality provisions of this Agreement, and that any such breach would cause the other party irreparable harm.
Accordingly, the parties hereto agree that in the event of any such breach or threatened breach hereof by a party or by its respective
Representatives, the other party to this Agreement shall be entitled, in addition to any other available remedies at law, to seek
equitable relief, including injunctive relief and specific performance without the posting of any bond or other security.

 

11.
MISCELLANEOUS

 

11.1
Entire Agreement. This Agreement constitutes the entire understanding between the parties with respect to the subject
matter hereof.

 

11.2
Notices. All notices and other communications required or permitted under this Agreement shall be in writing and
shall be sent by registered or certified mail (return receipt requested and postage prepaid), or delivered by hand, by messenger
or by a recognized overnight delivery service, addressed to each party as follows:

 

if
to Licensor:

 

ACCU-BREAK
PHARMACEUTICALS, INC.

Accu-Break
Pharmaceuticals, Inc.

6100
Hollywood Boulevard, Suite 207

Hollywood,
FL 33024

Telephone:
954-989-4150

E-mail:
r.goldfarb@accubreak.com

 

if
to Licensee:

 

INTIVA
BIOPHARMA INC.

4340
East Kentucky Avenue, Suite 206

Denver,
CO 80246

Telephone:

E-mail:
jfriedland@intivabiopharma.com

 

Each
such notice or other communication shall for all purposes of this Agreement be treated as effective or having been given (i) if
sent by registered or certified mail, the earlier of receipt and five (5) business days after dispatch, and (ii) if delivered
in person, by messenger, or by overnight courier, on the business day delivered.

 

    	CONFIDENTIAL	16	 

    	 

    

 

11.3
Amendments; Waivers. This Agreement may be amended or any of its terms or conditions may be waived only by a written
instrument executed by the parties or, in the case of a waiver, by the party waiving compliance. The failure of either party at
any time or times to require performance of any provision hereof shall in no manner affect its rights at a later time to enforce
the same. No waiver by either party of any condition shall be deemed as a further or continuing waiver of such condition or term
or of any other condition or term.

 

11.4
Assignment; Successors. This Agreement shall be binding upon and inure to the benefit of and be enforceable by the
parties hereto and their respective successors and permitted assigns; provided that this Agreement shall not be assignable by
Licensor without Licensee’s written consent (which consent shall not be unreasonably withheld, delayed or conditioned) except
for the right to receive royalties or other payments payable herein, and further provided that Licensee may, with the consent
of Licensor (which consent shall not be unreasonably withheld, delayed or conditioned), transfer its interest or any part thereof
under this Agreement to a wholly-owned subsidiary of Licensee or to any assignee or purchaser of the portion of its business associated
with the manufacture and sale of Licensed Product, so long as such transferee assumes and agrees to be bound by the provisions
of this Agreement and provided further that such transferee shall give to Licensor financial statements which financial statements
shall reflect that its tangible net worth is equal to or greater than Licensee’s net worth as reflected in Licensee’s
financial statement provided to Licensor at the time of such request. Except as provided in the immediately preceding sentence,
this Agreement shall be assignable by Licensee only with the consent in writing of Licensor, not to be unreasonably withheld,
provided that the proposed assignee has sufficient resources and capabilities to operate a business in the Licensed Field.

 

11.5
Force Majeure. Any delays in or failures of performance by either party under this Agreement shall not be considered
a breach of this Agreement if and to the extent caused by occurrences beyond the reasonable control of the party affected, including
but not limited to: acts of God, acts, regulations, or laws of any government, strikes or the concerted acts of workers, fires,
floods, explosions, riots, wars, rebellion, and sabotage. Any time for performance hereunder shall be extended by the actual time
of delay caused by such occurrence; provided, however, that either party shall have the right to terminate this Agreement
if any such extension endures for more than twelve (12) consecutive months.

 

11.6
Publicity. Neither party shall use the name of the other party, nor the officers or employees of the other party,
nor any adaptation thereof in any advertising, promotional or sales literature, publicity or in any document employed to obtain
funds or financing without the prior written approval of the party or individual whose name is to be used, such approval not to
be unreasonably withheld.

 

11.7
Governing Law. This Agreement shall be governed by and construed and interpreted in accordance with the laws of
the State of Colorado, without regard to its choice of law principles.

 

    	CONFIDENTIAL	17	 

    	 

    

 

11.8
Alternative Dispute Resolution. For any and all claims, disputes, or controversies arising under, out of, or in
connection with this Agreement, except issues relating to the validity, construction or effect of any Patent Right, which the
parties shall be unable to resolve within sixty (60) days, the party raising such dispute shall promptly advise the other party
of such claim, dispute, or controversy in a writing which describes in reasonable detail the nature of such dispute. By not later
than five (5) business days after the recipient has received such notice of dispute, each party shall have selected for itself
a representative who shall have the authority to bind such party and shall additionally have advised the other party in writing
of the name and title of such representative. By not later than ten (10) business days after the date of such notice of dispute,
such representatives shall agree upon a third party, which is in the business of providing Alternative Dispute Resolution (ADR)
services (hereinafter, “ADR Provider”) and shall schedule a date with such ADR Provider to engage in ADR. Thereafter,
the representatives of the parties shall engage in good faith in an ADR process under the auspices of the selected ADR Provider.
If within the aforesaid ten (10) business days after the date of the notice of dispute the representatives of the parties have
not been able to agree upon an ADR Provider and schedule a date to engage in ADR, or if they have not been able to resolve the
dispute within thirty (30) business days after the conclusion of ADR, the parties shall have the right to pursue any other remedies
legally available to resolve such dispute in either the state or federal courts of New York, to whose jurisdiction for such purposes
each of Licensor and Licensee hereby irrevocably consents and submits. Notwithstanding the foregoing, nothing in this Section
11.8 shall be construed to waive any rights or timely performance of any obligations existing under this Agreement.

 

11.9
Severability. If any provision(s) of this Agreement are or become invalid, are ruled illegal by any court of competent
jurisdiction or are deemed unenforceable under then current applicable law from time to time in effect during the term thereof,
it is the intention of the parties that the remainder of this Agreement shall not be affected thereby. It is further the intention
of the parties that in lieu of each such provision which is invalid, illegal or unenforceable, there be substituted or added as
part of this Agreement a provision which shall be as similar as possible in economic and business objectives as intended by the
parties to such invalid, illegal or enforceable provision, but shall be valid, legal and enforceable.

 

11.10
Independent Contractors. It is expressly agreed that Licensor, on the one hand, and Licensee, on the other hand,
shall be independent contractors and that the relationship between the two parties shall not constitute a partnership, joint venture
or agency. Neither Licensor, on the one hand, nor Licensee, on the other hand, shall have the authority to make any statements,
representations or commitments of any kind, or to take any action, which shall be binding on the other, without the prior written
consent of the other party to do so. All persons employed by a party shall be employees of such party and not of the other party
and all costs and obligations incurred by reason of any such employment shall be for the account and expense of such party.

 

11.11
Survival. Sections 5, 6, 7, 8, 9, 10 and 11 shall survive the expiration or termination of this Agreement.

 

11.12
Counterparts. This Agreement may be executed in two counterparts, each of which shall be enforceable against the
party actually executing such counterpart, and both of which together shall constitute one instrument.

 

11.13
Titles and Subtitles. The titles and subtitles used in this Agreement are used for convenience only and are not
considered in construing or interpreting this Agreement.

 

[signature
page follows]

 

    	CONFIDENTIAL	18	 

    	 

    

 

THE
PARTIES have duly executed this Agreement as of the date first shown above written.

 

[signature
page to Exclusive License Agreement]

 

	Licensor:
    	 	Licensee:
	ACCU-BREAK
    PHARMACEUTICALS, INC.	 	INTIVA
                                         BIOPHARMA INC.

        

	 	 	 
	BY:	/s/
    Elliot F. Hahn	 	BY:	/s/
    Alain Bankier
	NAME:	Elliot
    F. Hahn, Ph.D	 	NAME:	Alain
    Bankier
	TITLE:	Executive
    Chairman	 	TITLE:	Chief
    Strategy Officer and Director

 

    	CONFIDENTIAL	19

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00283-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00283-of-00352.parquet"}]]