Document:

EX-10.8

                        CASH COLLATERAL PLEDGE AGREEMENT

1.       GRANT OF PLEDGE., THERMODYNETICS, INC., a Delaware corporation having a
         principal place of business at 651 Day Hill Road, Windsor,  Connecticut
         (the "PLEDGOR"),  does hereby pledge,  assign,  transfer and deliver to
         CITIZENS   BANK  OF   MASSACHUSETTS   (hereinafter,   the  "BANK"),   a
         Massachusetts  state  chartered  bank with offices  located at 53 State
         Street,  Boston,  Massachusetts  02109, and does hereby grant to Bank a
         continuing  security  interest  in, the  Collateral  to secure the Debt
         Service Shortfall Obligations (as these terms are hereinafter defined).

2.       MODIFICATION AGREEMENT AND DEFINED TERMS. This agreement  (hereinafter,
         the "CASH  COLLATERAL  PLEDGE  AGREEMENT" or  "AGREEMENT") is delivered
         pursuant to the terms of that  certain  Modification  Agreement  by and
         between   the   Pledgor   and  the  Bank  dated  April  25,  2006  (the
         "MODIFICATION  AGREEMENT",  together  with  the  all  other  documents,
         instruments  and  agreements,   collectively,  the  "LOAN  DOCUMENTS").
         Capitalized  terms used herein and not otherwise  specifically  defined
         shall have the same meaning herein as in the Loan Documents.

3.       COLLATERAL.  The term  "Collateral"  as utilized  herein shall mean and
         include:  (a) $337,000.00  deposited herewith  (hereinafter,  the "Cash
         Collateral"); (b) that certain account established at the Bank entitled
         "Thermodynetics  Cash Collateral  Account" and having an account number
         of  1303814029  (hereinafter,  the "Cash  Collateral  Account") and all
         subsequent  deposits thereto;  and (c) all proceeds and products of any
         one or more of the  foregoing  whether  now  existing or arising at any
         time in the future.

4.       WARRANTIES AND REPRESENTATIONS.  Pledgor warrants and represent to, and
         agrees with, Bank that:

         a.       Pledgor is and shall be the owner of the  Collateral  free and
                  clear of all  pledges,  liens,  security  interests  and other
                  encumbrances  of every nature  whatsoever,  except in favor of
                  Bank;

         b.       Pledgor has the full right,  power and authority to pledge the
                  Collateral   and  to  grant  the  security   interest  in  the
                  Collateral as herein provided;

         c.       the execution,  delivery and  performance of this Agreement by
                  Pledgor does not and shall not result in the  violation of any
                  mortgage, indenture, material contract, instrument, agreement,
                  judgment,  decree, order, statute, rule or regulation to which
                  Pledgor is subject,  or by which it or any of its  property is
                  bound;

         d.       Pledgor shall not suffer or permit any lien or  encumbrance to
                  exist on or with respect to the Collateral  except in favor of
                  Bank;

         e.       this  Agreement  constitutes  the  legal,  valid  and  binding
                  obligation of Pledgor in accordance  with the terms hereof and
                  has been duly authorized, executed and delivered; and

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         f.       there is no material  litigation or administrative  proceeding
                  now  pending,  or to the  best  of its  knowledge  threatened,
                  against  Pledgor which if adversely  decided could  materially
                  impair the  ability  of  Pledgor  to pay or perform  Pledgor's
                  obligations hereunder.

5.       ACKNOWLEDGEMENT   OF   PLEDGOR'S   OBLIGATIONS.   The  parties   hereto
         acknowledge  and  agree  that  the  Pledgor  is  obligated  to the bank
         pursuant to, among others,  the following  documents,  instruments  and
         agreements:

         a.       Security Agreement (Inventory,  Accounts,  Equipment and other
                  Personal Property) dated September 4, 1992 between Pledgor and
                  the Bank;

         b.       Secured  Term Note dated  January 23,  2002 (the "TERM  NOTE")
                  made by Pledgor payable to the Bank in the original  principal
                  amount of $2,025,000.00;

         c.       Commercial  Promissory  Note  dated  November  10,  2005  (the
                  "COMMERCIAL NOTE") made by Pledgor and Turbotec Products, Inc.
                  payable  to the  Bank  in the  original  principal  amount  of
                  $183,000.00; and

         d.       Open-End Mortgage dated January 23, 2002 granted by Pledgor to
                  the Bank  and  encumbering  certain  property  located  on 651
                  Dayhill Road, Windsor, Connecticut, as amended by that certain
                  Amendment  to and  Confirmation  of Open  End  Mortgage  dated
                  November 10, 2005.

6.       PROCEDURES.

         a.       CASH  COLLATERAL   ACCOUNT.   Pledgor  agrees  that  the  Cash
                  Collateral paid to Bank and all proceeds thereof shall be held
                  by Bank in the Cash  Collateral  Account as  security  for the
                  Obligations  (as  defined  in  the  Modification   Agreement).
                  Payments to the Cash Collateral  Account shall be deposited by
                  Bank into the Cash  Collateral  Account and such account shall
                  be subject to  withdrawal  by order only of such  officers and
                  agents of Bank as Bank may designate from time to time for use
                  in  strict  accordance  with the  provisions  of,  and for the
                  purposes  stated in, this  Agreement and the provisions of the
                  Loan Documents.

         b.       PERMITTED INVESTMENTS.  Collected funds in the Cash Collateral
                  Account shall be invested in the Cash Collateral Account.  All
                  interest  earned on the Cash  Collateral  shall  remain in the
                  Cash  Collateral  Account to be applied in accordance with the
                  terms of this Agreement.

         c.       CHARGES.  Pledgor shall pay upon billing  therefore,  or there
                  shall be  deducted  from the Cash  Collateral  Account  or the
                  income  therefrom,  all regular  reasonable and actual service
                  fees,   maintenance  fees  and  transaction   charges  related
                  thereto.

         d.       USE OF CASH  COLLATERAL.  The Collateral,  including,  without
                  limitation,  the  Cash  Collateral  and  the  Cash  Collateral
                  Account, shall be held by Bank pursuant to the

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<PAGE>

                  terms of this Agreement and the  Modification  Agreement until
                  the  Obligations  under the Term Note and the Commercial  Note
                  have been satisfied in full.  Upon and After the occurrence of
                  an Event of  Default,  that Bank may apply  funds out the Cash
                  Collateral   Account  in  a  manner  determined  in  its  sole
                  discretion.

         e.       RELEASE. In the event that the Obligations under the Term Note
                  have been  satisfied in full,  and the  Obligations  under the
                  Commercial  Note  remain  due and  owing,  a portion  the Cash
                  Collateral Account,  except for an amount equal to $37,000.00,
                  shall be paid to  Pledgor  within  five (5)  Business  Days of
                  Pledgor's  written request.  In the event that the Obligations
                  under the Commercial Note have been satisfied in full, and the
                  Obligations  under  the Term  Note  remain  due and  owing,  a
                  portion of the Cash Collateral  Account,  except for an amount
                  equal to $300,000.00, shall be paid to Pledgor within five (5)
                  Business Days of Pledgor's  written  request.  At such time as
                  the  Obligations  under both the Term Note and the  Commercial
                  Note have been satisfied in full, the remaining balance in the
                  Cash  Collateral  Account,  if any,  shall be paid to  Pledgor
                  within five (5) Business  Days of Pledgor's  written  request.
                  Notwithstanding  the  foregoing,  provided  that no  Event  of
                  Default  exists,  Pledgor may request from Bank in  connection
                  with Pledgor's payment in full of the Obligations at Maturity,
                  the release of the  Collateral  in order to assist the Pledgor
                  in the  payment  in full of the  Obligations  and  Bank  shall
                  release such  Collateral  provided that (i) such Collateral is
                  solely  utilized  to  pay  the   Obligations,   and  (ii)  the
                  Obligations are paid in full at the time of such release.

7.       CONSENTS  AND  WAIVERS.  Pledgor  hereby  consents  to  the  extension,
         renewal, amendment,  modification or recasting from time to time of the
         obligations,  or  the  other  Loan  Documents,  or of  any  instrument,
         document  or  agreement  evidencing  or securing  any of the same,  and
         Pledgor  specifically waives any notice of the creation or existence of
         any of such obligations and of any such extension,  renewal, amendment,
         modification  or  recasting.  Pledgor also agrees that Bank may enforce
         its rights as against Pledgor,  Pledgor, the Collateral,  or as against
         any other  party  liable for the  Obligations,  or as against any other
         collateral  given for any of the  obligations,  in any order or in such
         combination as Bank may in its sole discretion  determine,  and Pledgor
         hereby  expressly  waives all  suretyship  defenses and defenses in the
         nature thereof, agrees to the release or substitution of any collateral
         hereunder or otherwise, waives any defense based upon the invalidity or
         unenforceability of any of the Loan Document,  and consents to each and
         all of the terms, provisions and conditions of this Pledge and Security
         Agreement and the other Loan Documents.  Upon an Event of Default, Bank
         may, at its option,  from time to time, and  notwithstanding any waiver
         at that  time or at any  other  time,  exercise  any one or more of the
         rights  and  remedies  of a  secured  party  afforded  by  the  Uniform
         Commercial  Code, as from time to time in effect in the Commonwealth of
         Massachusetts  or  afforded by other  applicable  law.  Requirement  of
         reasonable notice with respect to any sale or disposition shall be made
         if such notice is given in any manner  permitted  for notices under the
         Modification  Agreement  at least ten (10) days  before the time of the
         sale or other disposition or as otherwise required by applicable law.

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8.       EXPENSES. The reasonable and actual expenses of enforcing Bank's rights
         hereunder and Bank's  reasonable  attorneys' fees and other  reasonable
         legal  expenses  together  with  interest  thereon  shall be payable by
         Pledgor and shall be secured hereby and by the Loan Documents.

9.       SUCCESSORS   AND   ASSIGNS.   All  of  the   agreements,   obligations,
         undertakings,  representations and warranties herein made by Pledgor or
         Bank  shall  inure  to  the  benefit  of the  other  party,  and  their
         respective  successors and assigns, and shall bind Pledgor and Bank and
         their respective successors and assigns.

10.      FURTHER  ASSURANCES.  Pledgor agrees to execute such further assurances
         and  other  instruments  as Bank may deem  necessary  or  desirable  to
         effectuate the purposes of this Agreement.

11.      NO LIENS OR TRANSFERS BY PLEDGOR.  Pledgor agrees that until Pledgor is
         entitled to a return of the Collateral,  or so much thereof as remains,
         Pledgor shall not, without the express prior written consent of Bank in
         each instance, transfer the Collateral or any interest therein or enter
         into any  agreement for the transfer of such  Collateral,  or permit or
         suffer  any other  liens,  whether  or not  junior to the lien  created
         hereby,  to be created or to exist with respect to the Collateral.  The
         foregoing  shall  not by  implication  relieve  the  Pledgor  from  the
         restrictions upon liens set forth in the other Loan Documents.

12.      NOTICES.  Any notices given in connection  with this Agreement shall be
         in  writing  and  shall be  effective  only if given  according  to the
         provisions of the Modification Agreement.

13.      COUNTERPARTS.  This Agreement may be executed in several  counterparts,
         each of which when  executed and  delivered is an original,  but all of
         which together shall constitute one instrument. In making proof of this
         Agreement,  it shall not be  necessary  to produce or account  for more
         than one such  counterpart  which is executed by the party against whom
         enforcement of such agreement is sought.

                            [Signature Page Follows]

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<PAGE>

         IN WITNESS WHEREOF,  the parties hereto have executed this Agreement as
an instrument under seal on the dated as of April 25, 2006.

PLEDGOR:                                    THERMODYNETICS, INC.

                                            By:_________/s/_____________________
                                            Name:____________________________
                                            Title:_____________________________

BANK:                                       CITIZENS BANK OF MASSACHUSETTS

                                            By:_______/s/_______________________
                                            Name: James H. Herzog, Jr.
                                            Title: Vice President

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EXHIBIT 4.3

THE SECURITIES REPRESENTED HEREBY HAVE BEEN ACQUIRED BY THE HOLDER HEREOF FOR ITS OWN ACCOUNT
FOR INVESTMENT WITH NO INTENTION OF MAKING OR CAUSING TO BE MADE A PUBLIC DISTRIBUTION OF ALL OR
ANY PORTION THEREOF. SUCH SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 OR
ANY STATE SECURITIES LAWS AND MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED OR HYPOTHECATED, EXCEPT
PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT FILED UNDER SUCH ACT OR PURSUANT TO AN EXEMPTION
FROM REGISTRATION UNDER SUCH ACT.

Warrant to Purchase

Shares of Capital Stock

(Subject to Adjustment)

ARTES MEDICAL USA, INC.

COMMON STOCK PURCHASE WARRANT

Void after August 16, 2009

     Artes Medical USA, Inc., a Delaware corporation (the “Company”), hereby certifies that, for
value received, Tiffany Storm (including any successors and assigns, “Holder”), is entitled
immediately upon or after the date hereof, and subject to the terms set forth below, to purchase
from the Company any time or from time to time before the earlier of (i) 5:00 P.M. Pacific Standard
Time, on August 26, 2009 or (ii) the closing of (a) the sale, lease, transfer or conveyance of all
or substantially all of the assets of the Company, (b) a consolidation of the Company with, or
merger of the Company with or into, any person (including any individual, partnership, joint
venture, corporation, trust or group thereof) other than a consolidation or merger by the Company
with a subsidiary of the Company in which the Company is the continuing entity or (c) the initial
underwritten public offering of the Company’s common stock (the earlier to occur of (i) or (ii) the
“Expiration Date”), fully paid and nonassessable shares of the Company’s Common Stock (the “Warrant
Shares”), with the number and character of the Warrant Shares and the exercise price of the Warrant
Shares to be determined as follows:

	 	(a)	 	Number of Warrant Shares. This Warrant shall evidence the right of the
Holder to purchase ___Thousand (___000) Warrant Shares, at a price per share
(the “Warrant Price”) set forth below, subject to adjustments and all other terms and
conditions set forth in this Warrant [equivalent to August 16, 2004 invoice].
	 
	 	(b)	 	Exercise Price. The exercise price per Warrant Share (the “Exercise
Price”) shall be an amount equal to $___per share, subject to the provisions of
Section 5, as applicable. The parties agree that the parties are in agreement that the
consideration for such Warrant Shares shall be deemed fully paid in consideration of
consulting services rendered to the Company as of _________, 2004.

 

 

	 	(c)	 	Character of Warrant Shares. This Warrant shall evidence the right of
the Holder to purchase Common Stock of the Company.
	 
	 	(d)	 	Definitions. As used herein the following terms, unless the context
otherwise requires, have the following respective meanings:

	 	i.	 	The term “Common Stock” shall
mean the Common Stock of the Company.
	 
	 	ii.	 	The term “Company” includes any
entity which shall succeed to or assume the obligations of the
Company hereunder.
	 
	 	iii.	 	The Date of Grant shall be August
16, 2004.

     l. Exercise Date; Expiration. Subject to the provisions of Section 5.3, this Warrant
may be exercised by the Holder at any time or from time to time from the Date of Grant and ending
on the earlier of (i) August 16, 2009 or (ii) the Expiration Date defined above. After the
Expiration Date, this Warrant Agreement shall be of no further force or effect.

     2. Exercise of Warrant; Partial Exercise. This Warrant may be exercised in full by
the Holder by surrender of this Warrant, together with the Holder’s duly executed form of
subscription attached hereto as Schedule 1, to the Company at its principal office, (as
determined above) of the number of Warrant Shares to be purchased hereunder. The exercise of this
Warrant pursuant to this Section 2 shall be deemed to have been effected immediately prior to the
close of business on the business day on which this Warrant is surrendered to the Company as
provided in this Section 2, and at such time the person in whose name any certificate for Warrant
Shares shall be issuable upon such exercise shall be deemed to be the record holder of such Warrant
Shares for all purposes. As soon as practicable after the exercise of this Warrant, the Company at
its expense will cause to be issued in the name of and delivered to the Holder, or as the Holder
may direct, a certificate or certificates for the number of fully paid and nonassessable full
shares of Warrant Shares to which the Holder shall be entitled on such exercise, together with
cash, in lieu of any fraction of a share, equal to such fraction of the current market value of one
full Warrant Share as determined in good faith by the Board of Directors, and, if applicable, a new
warrant evidencing the balance of the shares remaining subject to the Warrant.

     3. Net Issuance.

          3.1 Right to Convert. In addition to and without limiting the rights of the Holder
under the terms of this Warrant, the Holder shall have the right to convert this Warrant (the
“Conversion Right”) into Warrant Shares as provided in this Section 3 at any time or from time to
time during the Exercise Period. Upon exercise of the Conversion Right with respect to shares
subject to the Warrant (the “Converted Warrant Shares”), the Company shall deliver to the Holder
(without payment by the Holder of any exercise price or any cash or other consideration) that
number of fully paid and nonassessable Warrant Shares computed using the following formula:

2

 

	 	 	 
	X = Y (A - B)

	 	 
	A
	 	 

     Where X = the number of shares of Warrant Shares to be delivered to the holder

                    Y = the number of Converted Warrant Shares

                    A = the fair market value of one Warrant Share on the Conversion Date (as defined below)

                    B = the per share exercise price of the Warrant (as adjusted to the Conversion Date)

No fractional shares shall be issuable upon exercise of the Conversion Right, and if the number of
shares to be issued determined in accordance with the foregoing formula is other than a whole
number, the Company shall pay to the Holder an amount in cash equal to the fair market value of the
resulting fractional share on the Conversion Date (as defined below). Shares issued pursuant to
the Conversion Right shall be treated as if they were issued upon the exercise of the Warrant.

          3.2 Method of Exercise. The Conversion Right may be exercised by the Holder by the
surrender of the Warrant at the principal office of the Company together with a written statement
specifying that the Holder thereby intends to exercise the Conversion Right and indicating the
total number of shares under the Warrant that the Holder is exercising through the Conversion
Right. Such conversion shall be effective upon receipt by the Company of the Warrant together with
the aforesaid written statement, or on such later date as is specified therein (the “Conversion
Date”). Certificates for the shares issuable upon exercise of the Conversion Right shall be
delivered to the Holder promptly following the Conversion Date.

          3.3 Determination of Fair Market Value. For purposes of this Section 3, fair market
value of a Warrant Share on the Conversion Date shall mean:

                    (1) If traded on a stock exchange, the fair market value of the Common Stock shall be deemed
to be the average of the closing selling prices of the Common Stock on the stock exchange
determined by the Board to be the primary market for the Common Stock over the ten (10) trading day
period (or such shorter period immediately following the closing of an initial public offering)
ending on the date prior to the Conversion Date, as such prices are officially quoted in the
composite tape of transactions on such exchange;

                    (2) If traded over-the-counter, the fair market value of the Common Stock shall be deemed to
be the average of the closing bid prices (or, if such information is available, the closing selling
prices) of the Common Stock over the ten (10) trading day period (or such shorter period
immediately following the closing of an initial public offering) ending on the date prior to the
Conversion Date, as such prices are reported by the National Association of Securities Dealers
through its NASDAQ system or any successor system; and

                    (3) If there is no public market for the Common Stock, then the fair market value shall be
determined by the Board of Directors of the Company in good faith.

3

 

     4. Limit on Rights of the Holder upon Exercise. The Holder acknowledges and agrees
that upon the exercise of this Warrant in full or in part, the following provisions shall apply to
the rights of the Holder as a holder of shares of the Company’s Common Stock:

          4.1 Market Stand-Off Agreement. During the period of duration specified by the
Company and an underwriter of Common Stock or other securities of the Company, following the
effective date of a registration statement of the Company filed under the Act, the Holder or any
future transferee will not, to the extent requested by the Company and such underwriter, directly
or indirectly sell, offer to sell, contract to sell (including, without limitation, any short
sale), grant any option to purchase or otherwise transfer or dispose of (other than to transferees
or donees who agree to be similarly bound) any securities of the Company held by it at any time
during such period except shares of capital stock included in such registration; provided,
however, that such agreement shall not exceed one hundred eighty (180) days and shall only
apply to the Company’s initial public offering.

                    In order to enforce the foregoing covenant, the Company may impose stop-transfer instructions
with respect to the Common Stock of the Holder or any future transferee (and the shares or
securities of every other person subject to the foregoing restriction) until the end of such
period.

     5. Adjustments to Conversion Price. The number and kind of Warrant Shares (or any
shares of stock or other securities which may be) issuable upon the exercise of this Warrant and
the exercise price hereunder shall be subject to adjustment from time to time upon the happening of
certain events, as follows:

          5.1 Dividends, Distributions, Stock Splits or Combinations. If the Company shall at
any time or from time to time after the date hereof make or issue, or fix a record date for the
determination of holders of Warrant Shares entitled to receive, a dividend or other distribution
payable in additional shares of common or preferred stock (as the case may be), then and in each
such event the exercise price hereunder then in effect shall be decreased as of the time of such
issuance or, in the event such a record date shall have been fixed, as of the close of business on
such record date, by multiplying the exercise price hereunder then in effect by a fraction: (a)
the numerator of which shall be the total number of Warrant Shares (assuming the exercise or
conversion into Warrant Shares of all outstanding securities of the Company that are convertible
into Warrant Shares and the conversion of all such Warrant Shares into Common Stock) issued and
outstanding immediately prior to the time of issuance or the close of business on such record date;
and (b) the denominator of which shall be the total number of Warrant Shares (assuming the exercise
or conversion into Warrant Shares of all outstanding securities of the Company that are convertible
into Warrant Shares and the conversion of all such Warrant Shares into Common Stock) issued and
outstanding immediately after the time of issuance or the close of business on such record date.
If the Company shall at any time subdivide the outstanding Warrant Shares, or if the Company shall
at any time combine the outstanding Warrant Shares, then the exercise price hereunder immediately
shall be decreased proportionally (in the case of a subdivision) or increased proportionally (in
the case of a combination). Any such adjustment shall become effective at the close of business on
the date the subdivision or combination becomes effective.

4

 

          5.2 Reclassification or Reorganization. If the Warrant Shares issuable upon the
exercise of this Warrant shall be changed into the same or different number of shares of any class
or classes of stock, whether by capital reorganization, reclassification or otherwise (other than a
subdivision or combination of shares or stock dividend provided for in Section 5.1 above, or a
reorganization, merger, consolidation or sale of assets provided for in Section 5.3 below), then
and in each such event the Holder shall be entitled to receive upon the exercise of this Warrant
the kind and amount of shares of stock and other securities and property receivable upon such
reorganization, reclassification or other change, to which a holder of the number of Warrant Shares
issuable upon the exercise of this Warrant would have received if this Warrant had been exercised
immediately prior to such reorganization, reclassification or other change, all subject to further
adjustment as provided herein.

          5.3 Merger, Consolidation or Sale of Assets. If at any time or from time to time
there shall be a capital reorganization of the Warrant Shares or a merger, consolidation or sale of
all or substantially all of the assets of the Company (other than a subdivision, combination,
reclassification or exchange of shares provided for elsewhere in this Section 5) of the Company,
then as a part of such reorganization, provision shall be made so that the Holder shall thereafter
be entitled to receive upon the exercise of this Warrant, the number of shares of stock or other
securities or property of the Company, resulting from such reorganization, merger, consolidation or
sale, to which a holder of the number of Warrant Shares issuable upon the exercise of this Warrant
would have received if this Warrant had been exercised immediately prior to such reorganization,
merger, consolidation or sale.

          5.4 Notice of Record Dates; Adjustments. In the event of, at any time prior to the
Expiration Date, an initial public offering of securities of the Company registered under the
Securities Act of 1933, as amended, or the consolidation or merger of the Company with or into
another Company (other than a merger solely to effect a reincorporation of the Company into another
state), or the sale or other disposition of all or substantially all the properties and assets of
the Company in its entirety to any other person, the Company shall provide to the Holder twenty
(20) days advance written notice of such public offering, consolidation, merger or sale or other
disposition of the Company’s assets, and this Warrant shall terminate unless exercised prior to the
date such public offering is declared effective by the Securities and Exchange Commission or the
occurrence of such consolidation, merger or sale or other disposition of the Company’s assets. The
Company shall promptly notify the Holder in writing of each adjustment or readjustment of the
exercise price hereunder and the number of Warrant Shares issuable upon the exercise of this
Warrant. Such notice shall state the adjustment or readjustment and show in reasonable detail the
facts on which that adjustment or readjustment is based.

     6. Replacement of Warrants. On receipt by the Company of evidence reasonably
satisfactory to the Company of the loss, theft, destruction or mutilation of this Warrant and, in
the case of any such loss, theft or destruction of this Warrant, on delivery of an indemnity
agreement reasonably satisfactory in form and amount to the Company or, in the case of any such
mutilation, on surrender and cancellation of such Warrant, the Company at its expense will execute
and deliver to the Holder, in lieu thereof, a new Warrant of like tenor.

5

 

     7. No Rights or Liability as a Stockholder. This Warrant does not entitle the Holder
hereof to any voting rights or other rights as a stockholder of the Company. No provisions hereof,
in the absence of affirmative action by the Holder to purchase Warrant Shares, and no enumeration
herein of the rights or privileges of the Holder, shall give rise to any liability of the Holder as
a stockholder of the Company.

     8. Miscellaneous.

          8.1 Transfer of Warrant/Representations of Holder. This Warrant shall not be
transferable or assignable in any manner and no interest shall be pledged or otherwise encumbered
by Holder without the express written consent of the Company, and any such attempted disposition of
this Warrant or any portion hereof shall be of no force or effect unless such disposition is in
compliance with this Warrant Agreement. Holder acknowledges that the warrants granted hereunder
are acquired for investment for such individual’s own account, not as a nominee or agent, and not
with a view to the resale or distribution of any part thereof, and Holder has no present intention
of selling, granting any participation in, or otherwise distributing the same. By executing this
Agreement, Holder further represents that Holder has no contract, undertaking, agreement or
arrangement with any person to sell, transfer or grant participation to such person or to any third
person, with respect to any of the common stock underlying this Warrant.

          8.2 Titles and Subtitles. The titles and subtitles used in this Warrant are for
convenience only and are not to be considered in construing or interpreting this Warrant.

          8.3 Notices. Any notice required or permitted under this Warrant shall be given in
writing and shall be sent by facsimile, overnight courier or mailed by certified or registered mail
postage prepaid, return receipt requested, to the facsimile number or address shown on the
signature pages to this Warrant Agreement, in accordance with this Section 8.3. Such notices or
other communications shall be deemed received upon receipt of a confirmation of facsimile receipt
or three (3) days after deposit in the mails, except as otherwise expressly provided in this
Warrant Agreement.

          8.4 Attorneys’ Fees. If any action at law or in equity is necessary to enforce or
interpret the terms of this Warrant, the prevailing party shall be entitled to reasonable
attorneys’ fees, costs and disbursements in addition to any other relief to which such party may be
entitled.

          8.5 Amendments and Waivers. Any term of this Warrant may be amended and the
observance of any term of this Warrant may be waived (either generally or in a particular instance
and either retroactively or prospectively), with the written consent of the Company and the Holder.
Any amendment or waiver effected in accordance with this Section 8.5 shall be binding upon the
Holder of this Warrant (and of any securities into which this Warrant is convertible), each future
holder of all such securities, and the Company.

          8.6 Severability. If one or more provisions of this Warrant are held to be
unenforceable under applicable law, such provision shall be excluded from this Warrant and the

6

 

balance of the Warrant shall be interpreted as if such provision were so excluded and shall be
enforceable in accordance with its terms.

          8.7 Governing Law. This Warrant shall be governed by and construed and enforced in
accordance with the laws of the State of California, without giving effect to its conflicts of laws
principles.

          8.8 English Language. This Warrant is written in the English Language, which shall be
controlling for all purposes. No translation of this Warrant into any other language shall be of
any force or effect in the interpretation of this Warrant or in a determination of the intent of
the parties hereto.

          8.9 Counterparts. This Warrant may be executed in any number of counterparts, each of
which shall be deemed an original, but all of which together shall constitute one and the same
instrument.

[REMAINDER OF THIS PAGE INTENTIONALLY LEFT BLANK]

7

 

Date: August 16, 2004

	 	 	 	 	 
	 	 	ARTES MEDICAL USA, INC.,

a Delaware corporation
	 
	 	 	 	 
	 

	 	By:	 	 
	 

	 	 	 	 
	 

	 	Name:
	 	Stefan M. Lemperle
	 

	 	Title:
	 	Chief Executive Officer
	 
	 	 	 	 
	ACKNOWLEDGED AND AGREED:
	 	 	 	 
	 
	 	 	 	 
	 
	 	 	 	 
	 
	 	 	 	 
	Tiffany Storm
	 	 	 	 

[SIGNATURE PAGE TO WARRANT]

8

 

SCHEDULE 1

FORM OF SUBSCRIPTION

(To be signed only on exercise of Warrant)

To: ARTES MEDICAL USA, INC.

     The undersigned, the holder of the Warrant attached hereto, hereby irrevocably elects to
exercise the purchase rights represented by such Warrant for, and to purchase thereunder,
_______* shares of Common Stock of Artes Medical USA, Inc., and herewith makes payment of
$________therefor, and requests that the certificates for such shares be issued in the name
of, and delivered to _____________, whose address is
_______________________.

	 	 	 
	 
	 	 
	 
	 	 
	 

	 	(Signature must conform in all respects to name of

the Holder as specified on the face of the Warrant)
	 
	 	 
	 
	 	 
	 

	 	 
	 

	 	(Print Name)
	 
	 	 
	 
	 	 
	 

	 	 
	 
	 	 
	 
	 	 
	 
	 	 
	 

	 	 
	 

	 	(Address)

	 	 	 	 	 
	Dated:

	 	 	 	 
	 

	 	 	 	 
	 

	 	 	 	 
	 

	 	 	 	 

* Insert here the number of shares as to which the Warrant is being exercised.

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00103-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00103-of-00352.parquet"}]]