Document:

Summary of 2008 Executive Officer Cash Bonus Plan

 Exhibit 10.44 
 SUMMARY OF 2008 EXECUTIVE OFFICER CASH BONUS PLAN 
 Overview and Purpose 
 This plan (the “2008 Bonus Plan”) was adopted by the Compensation Committee of the Board of Directors (the “Compensation Committee”) of Kosan
Biosciences Incorporated (the “Company”) on December 4, 2007 and is designed to offer incentive compensation to the Chief Executive Officer and Senior Vice Presidents of the Company by rewarding the achievement of specifically
measured corporate objectives and, if applicable, individual performance objectives. 
 Administration 
 The 2008 Bonus Plan will be administered by the Compensation Committee. The Compensation Committee will be responsible for approving, or recommending to the Board of
Directors for approval, any cash incentive awards to executive officers of the Company, including any incentive awards to the Chief Executive Officer. 
 Eligibility 
 The Chief Executive Officer and Senior Vice Presidents of the Company are eligible to participate in the 2008 Bonus Plan.

 Corporate and Individual Performance 
 The 2008 Bonus
Plan provides for the payment of cash bonuses to participants for the achievement of corporate objectives relating to certain clinical and partnering goals determined by the Compensation Committee. Each participant, other than the Chief Executive
Officer, will also be subject to key individual performance objectives. The actual bonuses payable for 2008 (if any) will vary depending on the extent to which actual performance meets, exceeds or falls short of the corporate objectives and, other
than with respect to the Chief Executive Officer, applicable individual performance objectives approved by the Compensation Committee, as determined by the Compensation Committee in its discretion, and on the level of the Company’s then current
or anticipated cash reserves. The Company’s Board of Directors or the Compensation Committee reserves the right to modify the corporate or individual performance objectives at any time based on business changes during the year. 
 Target Cash Bonus Amount 
 The 2008 Bonus Plan provides a target cash
bonus amount for the Chief Executive Officer and each Senior Vice President of the Company, expressed as a percentage of 2008 annual base salary for each participant.Second Modification of Lease

 Exhibit 10.1 
 SECOND MODIFICATION OF LEASE 
 This Second Modification of Lease (the “Second
Modification”) is made and entered into as of the 30th day of November, 2007 between BRC PROPERTIES, INC., an Ohio corporation (“Landlord”) and DOMINION HOMES, INC., an Ohio corporation (“Tenant”). 

WHEREAS, a certain Lease (the “Lease”) was executed July 21, 2003, by and between Landlord and Tenant, pursuant to which Tenant
leased 35,000 gross square feet of office space, being all of the building currently identified as 5000 Tuttle Crossing Blvd., Dublin, Ohio (the “Leased Premises”); 
 WHEREAS, the Lease was amended October 31, 2003 to reflect a change of address for the Leased Premises and to change the expiration date of
the Lease from September 30, 2018 to October 31, 2018; 
 WHEREAS, Landlord and Tenant mutually desire to further amend the
Lease to include an Early Termination Option for Tenant; 
 NOW THEREFORE, for good and valuable consideration, the sufficiency of
which hereby is acknowledged, Landlord and Tenant agree to amend the Lease to add the following Early Termination Option: 
 Early
Termination Option 
 Tenant shall have an option to terminate the Lease effective
at any time on or after December 1, 2007. Tenant may exercise its option by giving written notice to Landlord specifying the date the Lease shall terminate (the “Termination Date”), provided that the Termination Date shall be no
sooner than thirty (30) days after the date of Tenant’s notice. On or before the 15th day prior to the Termination Date, Tenant shall pay to
Landlord: (i) an early termination fee in the amount of Three Hundred Eighty-Five Thousand Dollars ($385,000.00); and (ii) Fixed Rent and any other charges due and payable under the Lease through the Termination Date. In the event Tenant
validly exercises its early termination option, Tenant waives its right to reimbursement for insurance premiums and real estate taxes to the extent paid in advance by Tenant. Tenant shall vacate the Leased Premises on or before the Termination Date;
shall leave the Leased Premises in broom-clean condition; and shall surrender the Leased Premises to Landlord free of Tenant’s personal property in accordance with, and subject to the terms of, Section 22 of the Lease. Tenant shall remain
liable for, and shall indemnify Landlord against, any loss, damage, claim or liability arising under the Lease with respect to matters occurring on or before the Termination Date. 
 Except as modified above, the Lease shall remain in full force and effect as originally written. Any ambiguity or inconsistency between the terms and
provisions of the Lease and prior amendment thereto, and the terms and provisions of this Second Modification, shall be resolved in favor of this Second Modification. 

 IN WITNESS WHEREOF, Landlord and Tenant have signed this Second Modification as of the date and
year set forth above. 
  

			
	 Landlord:

	 BRC Properties Inc., an Ohio corporation

		
	 By:
	 	 /s/ Terry E. George

	 Name:
	 	Terry E. George
	 Its:
	 	Vice President
	
	 Tenant:

	 Dominion Homes, Inc., an Ohio corporation

		
	 By:
	 	 /s/ William G. Cornely

	 Name:
	 	William G. Cornely
	 Its:
	 	Executive Vice President

 STATE OF OHIO 
 COUNTY OF FRANKLIN, ss: 
 On this 30th day of November, 2007, before me a Notary Public personally appeared Terry E. George, the Vice President of BRC Properties, Inc., an Ohio corporation, and acknowledged that he did
sign the foregoing instrument, and that the same is his free act and deed and the free act and deed of the corporation. 
 IN WITNESS
WHEREOF, I have hereunto subscribed my name and affixed my official seal on the date and year aforesaid. 
  

	
	 /s/ Kathy Kellenbarger

	 Notary Public

 STATE OF OHIO 
 COUNTY OF FRANKLIN, ss: 
 On this 30th day of November, 2007, before me a Notary Public personally appeared William G. Cornely, the Executive Vice President of Dominion Homes, Inc., an Ohio corporation, and acknowledged
that he did sign the foregoing instrument, and that the same is his free act and deed and the free act and deed of the corporation. 
 IN WITNESS WHEREOF, I have hereunto subscribed my name and affixed my official seal on the date and year aforesaid. 
  

	
	 /s/ Kathy Kellenbarger

	 Notary PublicAmendment No. 3 to Lease

 Exhibit 10.2 
 AMENDMENT NO. 3 TO LEASE 
 This Amendment No. 3 to Lease (the “Third
Amendment”) is made and entered into as of the 30th day of November, 2007 between BRC PROPERTIES, INC., an Ohio corporation f/k/a Borror Realty Company (“Landlord”) and DOMINION HOMES, INC., an Ohio corporation
(“Tenant”). 
 WHEREAS, a certain Lease was executed December 29, 1997, by and between Landlord and Tenant, pursuant to
which Tenant leased 39,504 gross square feet of office space, being all of the building previously identified as 5501 Frantz Road, Dublin, Ohio and currently identified as 4900 Tuttle Crossing Blvd., Dublin, Ohio (the “Leased Premises”);

 WHEREAS, the Lease was amended February 2, 1998 to provide for an expiration date of December 31, 2009; 
 WHEREAS, the Lease was amended November 30, 2005 to increase the monthly rental amount to $39,424.19 beginning December 1, 2005 and
continuing throughout the remaining lease term; 
 WHEREAS, Landlord and Tenant mutually desire to further amend the Lease;

 NOW THEREFORE, for good and valuable consideration, the sufficiency of which hereby is acknowledged, Landlord and Tenant agree to
amend the Lease as follows: 
  

	 	1.	Term – Effective November 30, 2007, the amended December 31, 2009 lease expiration date shall be deleted and a new ten-year lease term shall commence
December 1, 2007 and expire on November 30, 2017 (the “Revised Term”). 

  

	 	2.	Rent – Tenant agrees to pay to Landlord as Fixed Rent during the Revised Term, monthly installments in the amounts set forth below: 

  

				
	 Time Period
	  	Monthly Fixed Rent
Installment
	 December 1, 2007 to November 30, 2008
	  	$	41,150.00
	 December 1, 2008 to November 30, 2009
	  	$	41,561.50
	 December 1, 2009 to November 30, 2010
	  	$	41,973.00
	 December 1, 2010 to November 30, 2011
	  	$	42,384.50
	 December 1, 2011 to November 30, 2012
	  	$	42,796.00
	 December 1, 2012 to November 30, 2013
	  	$	43,207.50
	 December 1, 2013 to November 30, 2014
	  	$	43,619.00
	 December 1, 2014 to November 30, 2015
	  	$	44,030.50
	 December 1, 2015 to November 30, 2016
	  	$	44,442.00
	 December 1, 2016 to November 30, 2017
	  	$	44,853.50

 3. Renewal Option – Section 34 of the Lease is deleted. In lieu thereof, Tenant shall
have one option to extend the Revised Term on all the provisions contained in the Lease, except for Fixed Rent, for a period of five years beginning December 1, 2017 and expiring November 30, 2022 (the “Extended Term”). Tenant
may exercise its option by giving written notice (a “Renewal Notice”) to Landlord at least 180 days prior to November 30, 2017. Such option shall be void and of no effect if Tenant is in default on the date the Renewal Notice is
given, or on the date the Extended Term is to commence. Fixed Rent for the Extended Term shall be equal to fair market rental for similar Class A office buildings in the Dublin, Ohio area as of the date Tenant exercises its option; provided
that in no event shall Fixed Rent be less than the Fixed Rent payable by Tenant for the month immediately preceding commencement of the Extended Term. 
 Except as modified above, the Lease shall remain in full force and effect as originally written. Any ambiguity or inconsistency between the provisions of the Lease and prior amendments thereto and the terms and
provisions of this Third Amendment shall be resolved in favor of this Third Amendment. 
 IN WITNESS WHEREOF, Landlord and Tenant have
signed this Addendum No. 3 to Lease on 30, November, 2007. 
  

			
	 Landlord:

	 BRC Properties Inc., an Ohio corporation

		
	 By:
	 	 /s/ Terry E. George

	 Name:
	 	Terry E. George
	 Its:
	 	Vice President
	
	 Tenant:

	 Dominion Homes, Inc., an Ohio corporation

		
	 By:
	 	 /s/ William G. Cornely

	 Name:
	 	William G. Cornely
	 Its:
	 	Executive Vice President

  

 -2- 

 STATE OF OHIO 
 COUNTY OF
FRANKLIN, ss: 
 On this 30th day of November, 2007, before me a Notary Public personally appeared Terry E. George, the Vice President of BRC Properties, Inc., an Ohio corporation, and acknowledged that he did
sign the foregoing instrument, and that the same is his free act and deed and the free act and deed of the corporation. 
 IN WITNESS
WHEREOF, I have hereunto subscribed my name and affixed my official seal on the date and year aforesaid. 
  

	
	 /s/ Kathy Kellenbarger

	 Notary Public

 STATE OF OHIO 
 COUNTY OF FRANKLIN, ss: 
 On this 30th day of November, 2007, before me a Notary Public personally appeared William G. Cornely, the Executive Vice President of Dominion Homes, Inc., an Ohio corporation, and acknowledged
that he did sign the foregoing instrument, and that the same is his free act and deed and the free act and deed of the corporation. 
 IN WITNESS WHEREOF, I have hereunto subscribed my name and affixed my official seal on the date and year aforesaid. 
  

	
	 /s/ Kathy Kellenbarger

	 Notary Public

  

 -3-

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00133-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00133-of-00352.parquet"}], [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00133-of-00352.parquet"}]]