Document:

EX-10.24

 Exhibit 10.24 

Name 
 Address 

 

	Re:	 Decibel Therapeutics, Inc. Change in Control Agreement 

Dear: 
 The Company desires to provide you with
accelerated vesting of equity in the event of termination after a change in control (as defined herein) in certain circumstances. Accordingly, the Company agrees to provide a change in control benefit to you on the terms and conditions set forth in
this Change in Control Agreement (the “Agreement”) between Decibel Therapeutics, Inc. (the “Company,” which term shall include any successor by merger, consolidation, sale of substantially all of the
Company’s assets or otherwise) and (“you”), to be effective on ___________, 20[ ] (the “Effective Date”). Terms that are not defined herein where used appear on Exhibit A hereto. This benefit of
stock is in lieu of any acceleration benefit that would otherwise be payable to you under any employment agreement between you and the Company, any severance pay plan maintained by the Company for the benefit of Company employees, or by statute.
This Agreement does not represent an employment contract for any definite term or period, which means that either you or the Company can terminate your employment at any time, for any reason or no reason, and with or without notice, except as
expressly set forth in any employment agreement between you and the Company. 
  

	1.	 Equity Acceleration. If, during the 12 month period commencing upon the closing of a Change in Control,
(i) your employment ends as a result of Termination without Cause or your resignation for Good Reason, or (ii) the acquirer fails to assume the equity obligation (a “Qualifying Termination”) and subject to the
release requirement in Section 2 and to your continuing compliance with any restrictive covenant agreements between you and the Company, to the extent not already vested and exercisable, each Stock-Based Award shall become conditionally
accelerated by the applicable number of months on the chart set forth below, pending satisfying the release requirements, upon the occurrence of the Qualifying Termination, subject to compliance, if necessary, with Section 409A of the Internal
Revenue Code of 1986, as amended (“Section 409A”). 

  

							
	 If Employed:
	  	Accelerate each grant that
is not wholly vested by:	  		  	
	 0-12
months
	  	12 months	  		  	
	 >12 months
	  	24 months	  		  	
	 >24 months
	  	36 months	  		  	
	 >36 months
	  	48 months	  		  	

 The portion of each Stock-Based Award for which vesting is conditionally accelerated as set forth in the chart
above will only become fully vested and exercisable if and when you satisfy the release requirements, and any such tentatively vested portion will be forfeited retroactively to your date of termination if you either notify the Company that you will
not execute or will revoke the Release or the period for providing the Release expires without your complying with the release requirements. The Company may choose 

 
instead to permit you to exercise the conditionally vested portions of exercisable awards before the Release becomes effective and release to you any conditionally vested portions of other
Stock-Based Awards, subject to your undertaking to repay the Company in the manner determined by the Compensation Committee of the Board of Directors at such time if you fail to satisfy the release requirements thereafter. If you hold a Stock-Based
Award requiring exercise, the Company shall give you a reasonable period of notice and opportunity to exercise the Stock-Based Award. Notwithstanding the foregoing, to the extent permitted by the equity plan under which a Stock-Based Award was
granted, nothing in this Agreement shall preclude the Company from accelerating the vesting and exercisability of any or all Stock-Based Awards to an earlier period, and terminating unexercised awards as provided under the equity plan.
“Stock-Based Award” means any option, stock appreciation right, restricted stock, or restricted stock unit granted by the Company to you pursuant to the Company’s 2015 Stock Incentive Plan of Decibel Therapeutics, Inc.
or any successor plan or agreement, or any other Company equity compensation plan or agreement in which you participated. 
  

	2.	 Required Release. The Company’s obligation to provide equity acceleration under this Agreement is
subject (a) to your signing a release of claims in favor of the Company, confirmation of continued compliance with restrictive covenants, and post-employment cooperation on a form with customary terms to be supplied by the Company at or
promptly following the Date of Termination, which release becomes enforceable within 60 days (or such shorter period as the Company specifies) following the Date of Termination (the “Release”) and (b) to your meeting in
full your obligations under any restrictive covenant agreements in effect between you and the Company. The date for acceleration is the date of the first payroll whose cutoff date follows the date the Release becomes enforceable, provided that if
the 60 day period for providing an enforceable release extends into a calendar year subsequent to the year containing the Date of Termination, the acceleration will be no earlier than the first business day of such subsequent year.

  

	3.	 Amendment; Survival. This Agreement may be amended or modified only by a written instrument signed by
you and by an expressly authorized representative of the Company. The Company shall require any successor-in interest whether directly or indirectly by purchase, merger, consolidation, reorganization or
otherwise to all or substantially all of the business assets of the Company, expressly to assume and agree to perform this Agreement in the same manner and to the same extent as the Company would be required to perform if no such succession had
taken place. 

  

	4.	 Withholding; Section 409A. All benefits hereunder shall be subject to reduction for
applicable tax withholdings. If and to the extent any portion of any compensation or other benefit provided to you in connection with your employment termination is determined to constitute “nonqualified deferred compensation” within the
meaning of Section 409A and you are a specified employee as defined in Section 409A(a)(2)(B)(i), as determined by the Company in accordance with its procedures, by which determination you hereby agree that you are bound, such portion of
the compensation or other benefit shall not be paid or provided before the earlier of (i) the expiration of the six month period measured from the date of your “separation from service” (as determined

  
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under Section 409A) or (ii) the tenth day following the date of your death following such separation from service (or such later date as is required for administrative practicability
and permitted under Section 409A) (the “New Acceleration Date”). The acceleration of equity that otherwise would have been provided to you during the period between the date of separation from service and the New
Acceleration Date shall be provided to you in the first payroll period beginning after such New Acceleration Date. This Agreement is intended to comply with the provisions of Section 409A and this Agreement shall, to the extent practicable, be
construed in accordance therewith. Terms defined in this Agreement will have the meanings given such terms under Section 409A if and to the extent required to comply with Section 409A. In any event, the Company makes no representations or
warranty and will have no liability to you or any other person if any provisions of acceleration of equity under this Agreement are determined to constitute deferred compensation subject to Code Section 409A but not to satisfy the conditions of
that section. 
  

	5.	 No Mitigation. In no event shall you be obligated to seek other employment or take any other action by
way of mitigation of the acceleration of equity provided to you under any of the provisions of the Agreement, and in no event shall your equity hereunder be reduced by any compensation earned by you as a result of employment by another employer.

  

	6.	 Amendment to Conform to Law. The Company may amend this Agreement to comply with or avail itself of any
changes in common law or statutory law or regulations related to the terms of this Agreement. 

  

	7.	 Notices. Any and all notices, requests, demands and other communications provided for by this Agreement
shall be in writing and shall be effective when delivered in person or deposited in the United States mail, postage prepaid, registered or certified, and addressed to you at your last known address on the books of the Company or, in the case
of the Company, at its principal place of business, attention of the Chief Executive Officer, or to such other address as either party may specify by notice to the other actually received. 

 

	8.	 Entire Agreement. This Agreement constitutes the entire agreement between the parties and supersedes all
prior communications, agreements and understandings, written or oral, with respect to the terms and conditions of your compensation as a result of a Change in Control, including, as of the Effective Date, any such terms in a prior offer letter or
employment agreement between the Company and you. 

  

	9.	 Severability. Each provision of this Agreement shall be considered severable such that if any one
provision or clause conflicts with existing or future applicable law, or may not be given full effect because of such law, this shall not affect any other provision of the Agreement which, consistent with such law, shall remain in full force and
effect. All surviving clauses shall be construed so as to effectuate the purpose and intent of the parties. 

  
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	10.	 Headings. The headings and captions in this Agreement are for convenience only and in no way define or
describe the scope or content of any provision of this Agreement. 

  

	11.	 Counterparts. This Agreement may be executed in two or more counterparts, each of which shall be an
original and all of which together shall constitute one and the same instrument. 

  

	12.	 Governing Law. This Agreement shall be governed by the laws of the Commonwealth of Massachusetts without
regard to its conflicts of laws principles. 

  

									
	 EMPLOYEE
	 		 	 DECIBEL THERAPEUTICS, INC.

				
	 	 		 	By:	 	                
	 Name:
	 		 	 Name:

		 		 	 Title:

					
	 Dated:
	 	
                
	 		 	 Dated:
	 	
            

  
 4 

 Exhibit A 

Definitions 

Definitions. The following terms as used in this Agreement shall have the following meanings: 

 

	 	(a)	 “Affiliate” means any business entity in which the Company holds, directly or
indirectly, an equity, profits, or voting interest of 30% or more, and includes any subsidiary. 

  

	 	(b)	 “Cause” means, for purposes of this Agreement (i) material breach by you of any
other agreement with the Company or any of its Affiliates; (ii) other conduct by you that is reasonably likely to be materially harmful to the business, interests or reputation of the Company or any of its Affiliates; (iii) fraud,
embezzlement or other material dishonesty by you with respect to the Company or any of its Affiliates; (iv) your conviction of, or pleading guilty or no contest to, any crime involving moral turpitude or any; or (v) a breach of any confidentiality/non-competition/ non-solicitation agreement with the Company. With respect to a breach of (i) or (ii), you shall be given 30 days, after written notice of
such breach, to cure a breach to the reasonable satisfaction of the Company. 

  

	 	(c)	 “Change in Control” or “Change in Control of the Company” shall
mean the occurrence hereafter of any of the following, provided, in each case, that such event also constitutes a “change in control event” within the meaning of Treasury Regulation
Section 1.409A-3(i)(5) if necessary to avoid the imposition of additional taxes under Section 409A (as defined below): 

 

	 	(i)	 a change in the composition of the Board over a period of thirty-six
consecutive months or less such that a majority of the members of the Board ceases to be comprised of individuals who are Continuing Members; for such purpose, a “Continuing Member” shall mean an individual who is a member of
the Board on the date of this Agreement and any successor of a Continuing Member who is elected to the Board or nominated for election by action of a majority of Continuing Members then serving on the Board; 

 

	 	(ii)	 any merger or consolidation that results in the voting securities of the Company outstanding immediately prior
thereto representing (either by remaining outstanding or by being converted into voting securities of the surviving or acquiring entity) less than 50% of the combined voting power of the voting securities of the Company or such surviving or
acquiring entity outstanding immediately after such merger or consolidation; 

  

	 	(iii)	 any sale of all or substantially all of the assets of the Company to any Person; 

 

	 	(iv)	 the complete liquidation or dissolution of the Company; or 

  
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	 	(v)	 the acquisition of “beneficial ownership” (as defined in Rule
13d-3 under the Securities Exchange Act of 1934, as amended) of securities of the Company representing [50%] or more of the combined voting power of the Company’s then outstanding securities (other than
through a merger or consolidation or an acquisition of securities directly from the Company) by any Person, other than the Company, any trustee or other fiduciary holding securities under an employee benefit plan of the Company or any corporation
owned directly or indirectly by the stockholders of the Company in substantially the same proportion as their ownership of stock of the Company. 

  

	 	(d)	 “Good Reason” means any action on the part of the Company not consented to you in
writing that has the following effect or effects: (i) any action by the Company that results in a material diminution in your reporting relationship, authority, duties or responsibilities[; provided, however, that a sale or transfer of
less than all or substantially all of the business of the Company or any of its subsidiaries or other reduction of less than all or substantially all of its business or that of its subsidiaries, or the fact that the Company has become a subsidiary
of another company or that the securities of the Company are no longer publicly traded, shall not be taken into account when determining whether a material diminution in your authority, duties or responsibilities has occurred]; (ii) any
material reduction in your base salary; or (iii) the Company requires you to be based at any office or location that is more than 50 miles distant from your base office or work location immediately prior to relocation, except if such new
location is closer to your residence at the time such requirement is imposed. Notwithstanding the occurrence of any such event or circumstance, such occurrence shall not be deemed to constitute Good Reason unless (x) you give the Company the
notice of termination no more than 90 days after the initial existence of such event or circumstance (or series of either), (y) such event or circumstance has not been fully corrected within 30 days of the Company’s receipt of such notice
and (z) the Date of Termination occurs within 30 days following the end of the correction period if the Good Reason has not been corrected. 

  

	 	(e)	 “Termination without Cause” means a termination of your employment by the Company for
any reason other than (i) Cause, (ii) illness or injury, or (iii) death that occurs during the 12 month period commencing upon the closing of a Change in Control and subject to the release requirement in Section 2 and to your
continuing compliance with any restrictive covenant agreements between you and the Company. 

  

	
	Sincerely,
	
	   

	Title

  
 6 

 Please sign below for your acceptance of the terms of this Agreement. 

I accept the terms of this Agreement. 
  

					
	   
	 		 	   

	Employee	 		 	Date

  
 7EX-10.25

 Exhibit 10.25 

SUBLEASE AGREEMENT 
 THIS
SUBLEASE AGREEMENT, dated June 20, 2019 (this “Sublease”), is entered into by and between United HealthCare Services, Inc., a Minnesota corporation (“Sublandlord”), and Decibel Therapeutics, Inc., a Delaware
corporation (“Subtenant”). 
 RECITALS 

WHEREAS, Boylston West LLC, as landlord (“Landlord”), and Sublandlord, as tenant, are parties to that certain Lease, dated
December 23, 2015 (the “Original Lease”) and amended by the July 13, 2016 First Amendment to Lease (the “First Amendment” and, as so amended, the “Lease”), for certain premises consisting
of approximately 151,300 rentable square feet consisting of the entire eighth (8th), ninth (9th), tenth (10th), and eleventh (11th) floors and a portion of the fourth (4th) and sixth (6th) floors (the “Premises”) in the building located at 1325 Boylston Street, Boston, Massachusetts (the “Building”) and further described in the Lease; 

WHEREAS, a copy of the Lease is attached hereto as Exhibit A; and 

WHEREAS, Subtenant desires to sublease from Sublandlord, and Sublandlord desires to sublease to Subtenant, subject to Landlord’s Consent
(as defined below), the Subleased Premises (as defined below) pursuant to the terms of this Sublease. 
 NOW, THEREFORE, for good and
valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto agree as set forth below. 

AGREEMENT 
 1. Capitalized
Terms. Any capitalized terms not otherwise defined in this Sublease shall have the meanings ascribed thereto in the Lease. 
 2.
Subleased Premises; Grant; Proportionate Share; Permitted Use. Sublandlord hereby subleases unto Subtenant, and Subtenant hereby subleases from Sublandlord, a portion of the Premises comprised of approximately 16,940 rentable square feet on
the sixth (6th) floor of the Building, and identified on the attached Exhibit B (the “Subleased Premises”), together with the right to exercise in common with Sublandlord
and others entitled thereto, Sublandlord’s right to use the common areas under the Lease necessary or appropriate to Subtenant’s use of the Subleased Premises. Sublandlord and Subtenant agree that, for purposes of calculation of Rent
hereunder, the Subleased Premises contain 16,940 rentable square feet without regard to actual measurement. 
 3. “Subtenant’s
Proportionate Share” is eleven and two tenths percent (11.20%), which is the quotient of 16,940 rentable square feet in the Subleased Premises divided by 151,300 rentable square feet in the Premises. Subtenant shall only use the Subleased
Premises for the Permitted Use, and subject to the applicable terms of the Lease and to the terms of this Sublease. Sublandlord shall deliver the Subleased Premises to Subtenant in its as-is, where-is condition; provided, however, Sublandlord shall be obligated to deliver the space (i) in broom clean condition, (ii) free and clear of all tenants and occupants, and (iii) free of all of
Sublandlord’s personal property, except as expressly set forth herein. 

 4. Term. The term of this Sublease (the “Term”) commences on
Commencement Date and expires on January 31, 2027 (the “Expiration Date”) unless earlier terminated in accordance with the provisions of this Sublease. The “Commencement Date” is the later of (i) the date
on which Sublandlord receives Landlord’s Consent (as defined below); or (ii) September 1, 2019; provided, however, that if the Commencement Date has not occurred by December 31, 2019, then this Sublease is automatically void
ab initio unless, prior to December 31, 2019, the parties hereto expressly agree in writing to the contrary. The “Rent Commencement Date” is the date that is three (3) entire months after the Commencement Date (if
any). 
 5. Rent. “Rent” is the sum of Gross Rent and Additional Rent, both as defined below. Subtenant agrees to
pay to Sublandlord the total of the following sums as Rent for the Subleased Premises without delay, demand, notice or offset thereof or therefor: 
  

	 	5.1	 “Gross Rent” in accordance with attached Exhibit C. Commencing on the Rent Commencement
Date and thereafter for the remainder of the Term, Gross Rent is payable monthly in advance on the first day of each month with the first installment being payable in advance on the date that is five (5) business days after Subtenant receives a
fully executed copy of this Sublease. Gross Rent is inclusive of, and Subtenant is not required to separately reimburse Sublandlord for, Subtenant’s Proportionate Share of Tax Excess and Operating Cost Excess, as defined in the Lease.

  

	 	5.2	 “Additional Rent” is all amounts, other than Gross Rent, payable by Subtenant under this
Sublease. 

  

	 	5.3	 If Subtenant fails to pay any Rent when due then, in addition to the Rent, Subtenant shall pay Sublandlord a
late charge equal to five percent (5%) of the amount that was due to compensate for the administrative expense of monitoring and collecting Rent. In addition, if Sublandlord does not receive Rent within 10 business days after the date when Rent is
due, Subtenant shall pay interest on the unpaid amount from the date when it was due until it is paid at an interest rate equal to the lesser of (i) the rate announced by Bank of America, N.A. (or its successor) from time to time as its prime
or base rate (or if such rate is no longer available, a comparable rate reasonably selected by Sublandlord) plus two percent (2%), or (ii) the maximum applicable legal rate, if any. 

 

	 	5.4	 Notwithstanding anything in this Sublease to the contrary, if the rent due under the Lease with respect to the
Subleased Premises is abated in whole or in part during the Term pursuant to the terms of Sections 7.6, 14.1 and 14.3 of the Original Lease, or any other applicable provision of the Lease, then the Gross Rent due under this Sublease shall abate for
the same period and to the same extent as the rent for the Premises is abated pursuant to such Sections 7.6, 14.1 and 14.3 of the Original Lease, or any other provision of the Lease, as applicable. 

  
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	 	5.5	 Subtenant shall pay all Rent to Sublandlord pursuant to the deposit instructions attached hereto as Exhibit
D. 

  

	 	5.6	 The Subleased Premises are separately metered for electricity in order to monitor usage of electricity in the
Subleased Premises. Subtenant shall pay for all electricity charges shown on such meter directly to the supplier of the same. The Premises is separately metered for hot and chilled water in order to monitor usage of water in the Premises. Subtenant
shall pay Sublandlord for Subtenant’s Proportionate Share based upon the amount billed to Sublandlord by Landlord for Subtenant’s water usage in the Subleased Premises. The Subleased Premises are served by the central HVAC system provided
by Landlord, measured by one or more submeters. Subtenant shall be responsible for payment on an overtime basis for Landlord’s provision of HVAC to the Subleased Premises beyond the Normal Business Hours and on Holidays. Subtenant shall give
Landlord written notice by 12:00 noon each Friday as to any such needs for the following Saturday, Sunday or Holiday. 

6. Assumption of Obligations. Subtenant agrees to assume and perform, according to the terms of the Lease, all of the duties,
covenants, agreements and obligations of Sublandlord under the Lease, as the same may be applicable to the Subleased Premises as if Subtenant were the tenant under the Lease, except as expressly provided herein and except for the duty to make
payments to Landlord of rent and other charges. 
  

	 	6.1	 Subtenant agrees that it will perform all maintenance, repair and replacement obligations under the Lease that
are applicable to the Subleased Premises, and shall use, care for and maintain the Subleased Premises as required by the Lease. 

  

	 	6.2	 Subtenant shall neither do nor permit anything to be done which would cause the Lease to be terminated or
forfeited or any claims to accrue to the benefit of Landlord by reason of any right of termination or forfeiture reserved or vested in Landlord under the Lease, or any right for Landlord to claim damages under the Lease. 

 

	 	6.3	 It is hereby understood and agreed that Subtenant’s rights to use, possess and enjoy the Subleased
Premises are subject to the terms and conditions of the Lease and the rights and remedies of Landlord and Sublandlord thereunder. 

  

	 	6.4	 Subtenant agrees to indemnify Sublandlord against, and to hold Sublandlord harmless from, any liability,
damages, costs or expenses of any kind or nature, including court costs and reasonable attorneys’ fees, resulting from any failure by Subtenant to perform, keep and obey the terms of the Lease insofar as they are applicable to the Subleased
Premises. 

  
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	 	6.5	 Subtenant shall obtain and maintain the same insurance with respect to Subtenant’s liability and property
damage as Sublandlord is required to maintain pursuant to the Lease, and such insurance shall name Sublandlord as an additional insured, and also name Landlord as an additional insured. Subtenant shall, prior to the Commencement Date and in addition
to the requirements regarding certificates of insurance set forth in the Lease, provide certificates of such insurance to Sublandlord and Landlord. 

  

	 	6.6	 Except to the extent such terms and provisions are inconsistent with or are specifically contrary to the
express written provisions of this Sublease and except as provided in this Section 6.6, all of the terms, covenants and conditions of the Lease are by this reference incorporated herein and made a part of this Sublease with the same force and
effect as if fully set forth herein, provided, however, that for purposes of such incorporation, (i) the term “Lease” as used in the Lease shall refer to this Sublease; (ii) the term “Landlord” (and other
defined terms containing the term “Landlord” or any derivative thereof) as used in the Lease, and subject to the limitations of Sublandlord’s responsibilities to Subtenant under the Lease set forth in Section 16 of this Sublease,
shall refer to Sublandlord; (iii) the term “Tenant” (and other defined terms containing the term “Tenant” or any derivative thereof) as used in the Lease shall refer to Subtenant; (iv) the terms “Term” and
“Original Lease Term” as used in the Lease shall refer to the Term defined herein; and (v) the term “Premises,” as used in the Lease shall refer to the Subleased Premises; and (vi) the term “Annual Fixed Rent”
and “Monthly Fixed Rent” as used in the Lease shall refer to the Gross Rent due under this Sublease. In the event of any inconsistency between the provisions set forth in this Sublease and the provisions of the Lease, as incorporated
herein, the provisions of this Sublease shall control as between Sublandlord and Subtenant. Notwithstanding the foregoing, the following provisions of the Lease are expressly not incorporated into this Sublease: 

 

	 	(a)	 First Amendment Sections I(B), (C), (D) and (E); II; and IV; and 

 

	 	(b)	 Original Lease: 

  

	 	i.	 All reference to and provisions regarding “Tenant’s Work”, “Tenant’s Construction
Representative”, “Landlord’s Contribution”, and “Landlord’s Fit Plan Contribution”; 

  

	 	ii.	 Clauses (a) and (b) of Section 1.2; 

 

	 	iii.	 The second paragraph and clauses (A) through (E) of Section 2.2; 

 

	 	iv.	 Section 2.3; 

  

	 	v.	 Section 2.4; 

  

	 	vi.	 Section 2.5; 

  

	 	vii.	 Section 3.2; 

  

	 	viii.	 Section 4.2; 

  
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	 	ix.	 Section 4.3; 

  

	 	x.	 Section 5.1; 

  

	 	xi.	 Section 6.1; 

  

	 	xii.	 Section 6.2; 

  

	 	xiii.	 Section 7.4; 

  

	 	xiv.	 Section 7.5; 

  

	 	xv.	 The last sentence of the first paragraph of Section 8.1; 

 

	 	xvi.	 Article X; 

  

	 	xvii.	 Section 15.7; 

  

	 	xviii.	 Section 16.5; 

  

	 	xix.	 Section 16.9; 

  

	 	xx.	 Section 16.18; 

  

	 	xxi.	 Section 16.21; 

  

	 	xxii.	 Section 16.29; 

  

	 	xxiii.	 Section 16.31; 

  

	 	xxiv.	 Second paragraph of Section 16.30; and 

 

	 	xxv.	 Exhibits B-1, B-2, E-1, E-2, F, F-1, H, K, and L. 

7. Title and Possession. Subject the provisions of Section 22 below, Sublandlord covenants and agrees that it has full right and
authority to enter into this Sublease for the full Term hereof, and that Subtenant, so long as Subtenant is not in Default (as defined below), will have, hold and enjoy quiet possession of the Subleased Premises for the Term herein granted. 

8. Sublease and Assignment. Except as otherwise permitted pursuant to Article XII of the Original Lease, as incorporated into this
Sublease, Subtenant shall not assign this Sublease or further sublease any portion of the Subleased Premises voluntarily or by operation of law without the prior written consent of Sublandlord and Landlord, which consent Sublandlord shall not
unreasonably withhold in the event Landlord consents to the same. Subtenant will not pledge its interest hereunder, or allow liens to be placed on such interest, or suffer this Sublease or any portion thereof to be attached or taken upon execution.
No assignment or further subleasing, even with the consent of Sublandlord and Landlord, will relieve Subtenant from liability for payment of the Rent herein provided for or from the obligation to keep and be bound by all of the terms, conditions and
covenants of this Sublease. 

  
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 9. Damage, Destruction or Condemnation. In the event of damage or destruction of the
Subleased Premises or the taking of all or any part thereof under the power of eminent domain, this Sublease will terminate if the Lease is terminated as a result thereof, and the Rent payable hereunder will abate for as long as and in the same
proportion as the Rent due from Sublandlord to Landlord under the Lease abates as a result thereof. If this Sublease is not so terminated, the provisions of the Lease with regard to restoration of the Subleased Premises shall control. 

10. Mutual Release and Waiver of Subrogation. Notwithstanding any provision of this Sublease or the Lease to the contrary, Sublandlord
and Subtenant each hereby waives any and all rights of recovery, claim, action or cause of action, against the other and against Landlord, their agents (including partners, both general and limited), officers, directors, shareholders or employees,
for any loss or damage that may occur to the Subleased Premises, or any improvements thereto, or the Building, or any improvements thereto, or any property of such party therein, by reason of fire, the elements, or any other cause which could be
insured against under the terms of standard fire and extended coverage insurance policies, regardless of cause or origin, including negligence of the other party hereto, its agents, officers or employees, provided that Subtenant will not be released
to the extent that Sublandlord is not released from liability under the Lease, and each covenants that its insurers will hold no right of subrogation against such other party. 

11. Alterations. The parties agree that Subtenant is taking the Subleased Premises as is, where is, and with all faults. Subtenant
shall not make any alterations, additions or improvements to the Subleased Premises without the prior written consent of Landlord and Sublandlord, which consent Sublandlord shall not withhold in the event Landlord consents to the same. All
alterations, additions and improvements that are approved must be made at Subtenant’s sole cost and expense and shall be completed in accordance with Article IX of the Original Lease. At the time Sublandlord and Landlord approves any of
Subtenant’s alterations, additions or improvements, Sublandlord and Landlord shall notify Subtenant which of the subject alterations, additions or improvements shall be required to be removed by Subtenant at the end of the Term. If either
Landlord or Sublandlord shall give such notice, Subtenant shall remove the same prior to the expiration of the Term in accordance with Section 14 hereof. Notwithstanding the foregoing or anything to the contrary contained in this Sublease,
Subtenant shall not be obligated to remove any of Subtenant’s alterations, additions or improvements unless such alterations, additions or improvements are Atypical Improvements (as such term is defined in the Original Lease). 

12. Default. Upon the occurrence of a Default, Sublandlord has all of the rights and remedies against Subtenant that would be available
to Landlord against Sublandlord in the event of a default by Sublandlord under the Lease. The occurrence of any of the following shall constitute a material breach of this Sublease and a “Default” by Subtenant: (a) failure to
pay Rent or any other amount within five (5) days after receipt of written notice from Sublandlord to Subtenant of such late payment (or Sublandlord having rightfully given the written notice specified herein to Subtenant twice in any twelve
(12) month period, Subtenant shall fail thereafter in that twelve (12) month period to pay the Rent or any other monetary amount due under this Sublease on or before the date on which the same becomes due and payable); (b) all those items
of default set forth in the Master Lease which remain uncured after the cure period provided in the Master Lease, less two (2) business days; and/or (c) Subtenant’s failure to perform timely and subject to any cure periods any other
material provision of this Sublease or the Lease as incorporated herein. 

  
 -6- 

 13. Notices. All notices and notifications under this Lease to be sent from one party
to the other must be in writing and sent by a nationally recognized private carrier of overnight mail (e.g., Federal Express), with signature required upon delivery, to either party as set forth below. Each such communication is deemed to have been
given to, or served upon, the party to which addressed one (1) business day after the date the same is deposited with the courier. Any party hereto may change its address for the service of notice hereunder by serving written notice hereunder
upon the other party hereto, in the manner specified above, at least ten (10) days prior to the effective date of such change. 
  

			
	To Sublandlord:	  	 United HealthCare Services, Inc.
 Lease
Administration - MN008-W310
 9900 Bren Road East
 Minnetonka,
MN 55343

		
	To Subtenant:	  	 Decibel Therapeutics, Inc.
 1325 Boylston
Street, Suite 500
 Boston, MA 02215
 Attention: General
Counsel
  
 With a copy to:

 
 Goodwin Procter LLP

100 Northern Avenue
 Boston, MA 02210

Attention: Michelle C. Shea, Esq.

 14. Surrender of Subleased Premises. Upon the expiration or earlier termination of the Term of this
Sublease, Subtenant will quit and surrender possession of the Subleased Premises to Sublandlord in the condition required by Section 16.4(B) of the Original Lease; however, in no event shall Subtenant be obligated to remove any Furniture (as
defined below) or restore any alterations or improvements currently existing in the Subleased Premises as of the Commencement Date. To the extent Subtenant’s property remains in the Subleased Premises after the expiration of the Term such
property is deemed abandoned and Sublandlord has the right to remove and store the same at Subtenant’s cost, or to use assert control and ownership over the same. At least sixty (60), but not more than ninety (90), days prior to the Expiration
Date, Subtenant shall submit a written notice to Sublandlord and Landlord (the “Surrender Condition Notice”) to schedule a joint inspection with Sublandlord and Landlord to inspect the Subleased Premises to identify the scope of
work that Subtenant must complete, at Subtenant’s expense, to satisfy its surrender obligations under this section. If Subtenant either or both fails to deliver the Surrender Condition Notice to, or jointly inspect the Subleased Premises with,
Sublandlord and Landlord, then Sublandlord’s and/or Landlord’s determination of the required work shall be dispositive. 

  
 -7- 

 15. Termination of Lease. It is understood and agreed by and between the parties
hereto that the existence of this Sublease is dependent and conditioned upon the continued existence of the Lease, and in the event of the termination of the Lease, this Sublease automatically will be terminated; provided, however, that this
provision will not be deemed to release Sublandlord from liability if the Lease is terminated by reason of a Default by Sublandlord as tenant under the Lease, which Default did not result, in whole or in part, from a Default by Subtenant hereunder.
Subtenant will have no recourse against Sublandlord if the Lease is terminated by reason of a Default by Subtenant hereunder, or by any reason other than a Default by Sublandlord under the Lease. 

16. Benefits of the Master Lease; Services. Sublandlord agrees that Subtenant shall be entitled to receive all services, utilities,
repairs and restorations to be provided by Landlord to Sublandlord under the Lease with respect to the Subleased Premises. Except as expressly provided in this Sublease, Subtenant shall look solely to Landlord for all such services, utilities,
repairs and restorations and shall not require Sublandlord to perform any such services, utilities, repairs and restorations. Subtenant acknowledges that Sublandlord will have no responsibilities or liability for Landlord’s failure to provide
such services, utilities, repairs and restorations; except to the extent Sublandlord may interfere in the provision of such services, utilities, repairs and restorations by Landlord. Sublandlord will use commercially reasonable efforts to cause
Landlord to comply with all obligations of Landlord under the Lease with respect to the delivery of services, utilities, repairs and restorations to the Subleased Premises, but will not be obligated to commence litigation in connection therewith.

 With respect to the HVAC system within the Subleased Premises, Sublandlord specifically agrees to maintain at all times a service
contract during the Term. If Sublandlord elects to provide its own janitorial services within the Premises, pursuant to Section 7.3 of the Original Lease, Sublandlord shall not make such election with respect to the Subleased Premises without
Subtenant’s prior written consent. If Subtenant shall not consent to such election by Sublandlord, Sublandlord shall not elect to provide its own janitorial services with respect to the Subleased Premises so that Landlord shall not cease to
provide janitorial services within the Subleased Premises. If Subtenant shall consent to such election by Sublandlord, and if upon Sublandlord’s exercise of such election Landlord ceases providing janitorial services within the Subleased
Premises, Sublandlord shall provide such janitorial services within the Subleased Premises and such services shall be performed in compliance with the requirements set forth in Sections 9.2, 9.3 and 9.4 of the Original Lease, at no additional cost
to Subtenant. 
 17. Waiver. A waiver by any Default, breach or failure under this Sublease will not be construed as a waiver of any
subsequent or different Default, breach or failure. 
 18. Inspection. Sublandlord shall, upon reasonable prior notice (except in the
case of emergency), have the right to enter the Subleased Premises during the Normal Business Hours (except at any time in the case of emergency) for the purposes of inspecting the condition of same. Notwithstanding the foregoing, except in the
event of an emergency, Subtenant shall have the right to have a representative of Subtenant accompany Sublandlord at such times Sublandlord shall require access to the Subleased Premises; provided, however, if Subtenant’s representative is not
available or does not elect to accompany Sublandlord at the times that Sublandlord has requested such access, then such unavailability shall not prohibit or otherwise restrict Sublandlord’s access to the Subleased Premises, and Sublandlord may
access the Subleased Premises with or without Subtenant’s representative present. 

  
 -8- 

 19. Holding Over. Subtenant has no right to hold over after the expiration or earlier
termination of the term hereof. Subtenant will indemnify Sublandlord for any costs incurred by Sublandlord as a result of its failure to deliver the Premises to Landlord upon the expiration of the term of the Lease and Subtenant is also liable to
Sublandlord for Rent during such holdover at the rate of one hundred fifty percent (150%) of the Rent in effect as of the expiration of the Term of this Sublease. Acceptance by Sublandlord of Rent after such expiration or earlier termination will
not constitute consent to a holdover hereunder or result in a renewal. The foregoing provisions of this section are in addition to, and will not limit, Sublandlord’s right of reentry or any other rights of Sublandlord hereunder or as otherwise
provided by law. 
 20. Successors and Assigns. All of the terms, covenants, provisions and conditions of this Sublease are binding
upon and inure to the benefit of the parties hereto and their respective successors and permitted assigns. 
 21. Captions. The
captions used on the sections of this Sublease are for convenience only, are not a part of this Sublease, and are not to be considered in the interpretation hereof. 

22. Consent of Landlord. This Sublease is contingent upon approval by Landlord manifested by Landlord’s execution of a written
consent hereto (“Landlord’s Consent”), which Landlord’s Consent must be in a form reasonably acceptable to Subtenant and must expressly state that Landlord agrees that this Sublease does not significantly alter or
eliminate any of Sublandlord’s rights and options under the Lease, including, without limitation, signage rights, parking rights, and options to expand or contract the Premises, or extend or shorten the term of the Lease. Unless and until
Landlord so consents in writing to this Sublease, this Sublease is of no force or effect, and the parties hereto have no liability or obligation to each other. Subtenant shall reimburse Sublandlord for any amounts charged by Landlord in connection
with Landlord’s consenting to this Sublease, regardless if Landlord consents to this Sublease, and such reimbursable amounts are Additional Rent for purposes of this Sublease. Subtenant shall reimburse Sublandlord for those amounts within ten
(10) days’ after receipt of Sublandlord’s written request therefor. 
 23. Relationship of Parties. This Sublease does
not and will not create the relationship of principal and agent, or of partnership, or of joint venture, or of any other association between Sublandlord and Subtenant, the sole relationship between the parties hereto being strictly that of landlord
and tenant. 
 24. Broker’s Warranty. Sublandlord and Subtenant warrant and represent that they have dealt with no real estate
brokers in connection with this Sublease other than Jones Lang LaSalle Americas, Inc. (or an affiliate thereof) and CB Richard Ellis (or an affiliate thereof). No other brokers are entitled to any commission on account of this Sublease. The party
who breaches this warranty will defend, hold harmless and indemnify the other from any loss, damage or expense, including reasonable attorneys’ fees, arising from the breach. 

  
 -9- 

 25. Non-Disclosure. Neither Sublandlord nor
Subtenant shall publicize in a medium of general circulation available to the general public (e.g., trade journals, newspapers, radio, television, internet, etc.) the transaction evidenced by this Sublease. The foregoing prohibition is not
applicable to disclosures required by applicable laws (including, but not limited to SEC disclosure requirements), disclosures made in connection with efforts to sell or finance the Building, or non-published
statements made in the ordinary course of Sublandlord’s or Subtenant’s business. 
 26. Subordination. Subtenant
acknowledges that Sublandlord has executed the Non-Disturbance and Attornment Agreement attached hereto as Exhibit E, and that this Sublease is subject to the provisions of that agreement, including the subordination provisions therein.
Subtenant agrees to comply with the terms and provisions of that agreement to the extent that they apply to the Subleased Premises. 
 27.
Counterparts; Signatures. This Sublease may be executed in any number of counterparts, all of which are considered one and the same Sublease notwithstanding that all parties hereto have not signed the same counterpart. Signatures of this
Sublease which are transmitted by either or both electronic or telephonic means (including, without limitation, email) are valid for all purposes. Any party shall, however, deliver an original signature of this Sublease to the other party upon
request. 
 28. Furniture. Subtenant shall have, as appurtenant to the Subleased Premises, the use of the furniture located in the
Subleased Premises as of the Commencement Date (the “Furniture”) during the Term. Promptly after the Commencement Date, Sublandlord and Subtenant shall execute a furniture inventory which shall list the Furniture, substantially in
the form attached hereto as Exhibit F (the “Furniture Inventory”). The Furniture is provided “AS-1S/WHERE IS” and without warranty by Sublandlord as to its condition or
usability. Sublandlord shall maintain property insurance for the Furniture. Subtenant acknowledges that to the extent it deems appropriate Subtenant has inspected the Furniture and found the same to be in acceptable condition. Subject to
Sublandlord’s insurance obligations herein, Subtenant shall repair and maintain the Furniture so that it will remain in the same condition as when delivered to Subtenant, ordinary wear and tear from proper use excepted. At the expiration or
earlier termination of the Term, Subtenant shall return the Furniture to Sublandlord in the condition required hereunder. Notwithstanding the foregoing or anything to the contrary contained in this Sublease, during the Term, Subtenant shall have the
right, at Subtenant’s sole cost, to disassemble any or all of the partitions located in the Subleased Premises as of the Commencement Date, Sublandlord shall, at Sublandlord’s sole cost, remove the same from the Subleased Premises, and
such partitions shall no longer be designated as Furniture that Subtenant is required to maintain during the Term or return to Sublandlord at the expiration or earlier termination of the Term. 

29. Parking. Subject to the terms and provisions of the Lease, Sublandlord shall provide Subtenant with thirteen (13) of
Sublandlord’s unreserved parking spaces in a location reasonably acceptable to Sublandlord in the Garage and at the monthly rate charged from time-to-time under the Lease. Subtenant shall pay amounts due
under this section for the parking spaces as Additional Rent to Sublandlord with Subtenant’s monthly payment of Gross Rent under this Sublease. 

  
 -10- 

 30. Sublandlord Covenants and Representations. Sublandlord covenants and agrees that
Sublandlord: (i) shall cause all rent to be paid under the Lease as and when due and payable under the Lease; (ii) shall observe and perform the other terms, provisions, covenants and conditions of the Lease to be observed and performed by
Sublandlord, except and to the extent that such terms, provisions, covenants and conditions are assumed by Subtenant hereunder; (iii) shall not voluntarily terminate the Lease except pursuant to a right of termination arising out of casualty or
condemnation expressly set forth in the Lease and shall not amend the Lease in a manner adverse to Subtenant in any material respect; (iv) shall not take any action or fail to perform any act that results in a breach or default under the Lease
to the extent any such failure to perform such act adversely affects the rights of Subtenant under this Sublease, including, without limitation, the right of Subtenant to receive all services, utilities, repairs and restorations to be provided by
Landlord to Sublandlord under the Lease with respect to the Subleased Premises or the ability of Subtenant to seek or obtain the approval or consent of Landlord or the right of Subtenant to use and occupy the Subleased Premises for the purposes set
forth in this Sublease. 
 Sublandlord represents to Subtenant that: (a) Sublandlord has not received any written notice of default
under the Lease, except for any defaults that Sublandlord has cured and Landlord is no longer claiming to exist, and to the actual knowledge, without any investigation, of Sublandlord, Sublandlord is not in default of any of Sublandlord’s
obligations under the Lease; (b) Sublandlord has not sent to Landlord any written notice stating that Landlord is in default of any of Landlord’s obligations under the Lease; (c) Sublandlord has not received any written notice that
any work is required under the Lease or by applicable law to be done in the Subleased Premises; and (d) Sublandlord has not received any written notice of violation of any laws, ordinances, codes, rules, regulations or requirements affecting
the Subleased Premises. 
 31. Limited Liability. In no event shall the partners, principals, members, officers, stockholders,
directors, employees or agents of either Sublandlord or Subtenant be personally liable for the performance of that party’s obligations under this Sublease. 

32. Miscellaneous. If any provision of this Sublease is held by the final judgment of any court of competent jurisdiction to be
illegal, invalid or unenforceable, the validity of the remaining portions or provisions must not be impaired or affected, and the rights and obligations of the parties must be construed and enforced as if this Sublease did not contain that certain
part, term or provision held to be illegal, invalid or unenforceable. This Sublease constitutes the entire agreement between Sublandlord and Subtenant with respect to the Subleased Premises and may be amended or altered only by written agreement
executed by both parties, and supersedes all prior agreements, whether written or oral, between the parties. This Sublease, and the rights and obligations of the parties hereto, must be construed and enforced in accordance with the laws of the
Commonwealth of Massachusetts. 
 33. Signage. Subtenant may install signage identifying Subtenant, which may include
Subtenant’s corporate logo and colors, on the entrance door to the Subleased Premises and/or within the Subleased Premises, which signage shall be subject to Sublandlord’s and Landlord’s approval. 

  
 -11- 

 34. Card Access System. Subtenant shall have the right to install its own access
controlled security system within the Subleased Premises, provided that: (i) Subtenant obtains all necessary governmental permits and approvals for such use, (ii) any such system shall be compatible with the existing Premises access
control system and tied into the Premises’ fire alarm system, and (iii) the plans and specifications for any such system shall be subject to the prior approval of Sublandlord and Landlord in all respects (which approval Sublandlord shall
not withhold in the event Landlord approved the same). The work to install any such security system shall be performed in accordance with Article IX of the Original Lease. 

35. Security Deposit. Subtenant shall deliver to Sublandlord a clean, irrevocable letter of credit (the “Letter of
Credit”) established in Sublandlord’s (and its successors’ and assigns’) favor in the amount of $588,666.00, subject to reduction as set forth herein, issued by a federally insured banking or lending institution reasonably
acceptable to Sublandlord and in other form and substance reasonably acceptable to Sublandlord. 
  

	 	35.1	 The Letter of Credit shall specifically provide for partial draws, shall be extended annually, without
amendment, for additional one-year periods, shall have a term that commences on the Commencement Date and expires on the Expiration Date, and shall by its terms be transferable by the beneficiary thereunder.

  

	 	35.2	 If Subtenant fails to make any payment of rent or other charges due to Sublandlord under the terms of this
Sublease, or otherwise Defaults hereunder, Sublandlord, at Sublandlord’s option, may make a demand for payment under the Letter of Credit in an amount equal to the amounts then due and owing to Sublandlord under this Sublease.

  

	 	35.3	 In the event that Sublandlord draws upon the Letter of Credit, Subtenant shall present to Sublandlord a
replacement Letter of Credit in the full Letter of Credit amount satisfying all of the terms and conditions of this article within ten (10) business days after receipt of notice from Sublandlord of such draw. Subtenant’s failure to do so
within such 10-business-day period will constitute a Default hereunder, and upon such Default, Sublandlord shall be entitled to immediately exercise all rights and
remedies available to it hereunder, at law or in equity. 

  

	 	35.4	 Provided Subtenant is not then in Default under this Sublease, the balance of the Letter of Credit shall reduce
during the Term of this Sublease as follows: 

  

					
	 Period
	  	Letter of Credit Amount	 
	 Rent Year 2
	  	$	490,555.00	 
	 Rent Year 3
	  	$	392,444.00	 
	 Rent Year 4
	  	$	294,333.00	 
	 From the commencement of Rent Year 5 through January 31, 2027
	  	$	196,222.00	 

 For purposes hereof, “Rent Year” shall mean a period of twelve (12) consecutive months
commencing on the Rent Commencement Date, and each successive twelve (12) month period thereafter; provided, however, that if the Rent Commencement Date is not the first day of a month, then the second Rent Year shall commence on the first day
of the month immediately following the first anniversary of the Rent Commencement Date. 
 [The balance of this page is intentionally
left blank.] 

 IN WITNESS WHEREOF, the parties hereto have caused these presents to be executed as of the
day and year first above written. 
  

							
	 SUBLANDLORD
  

UNITED HEALTHCARE SERVICES, INC.,

a Minnesota corporation
	  	 SUBTENANT
  

DECIBEL THERAPEUTICS, INC.,

a Delaware corporation

				
	By:	 	 /s/ Adam Wilford
	  	By:	  	 /s/ Steven H. Holtzman

	 Name: Adam Wilford
 Title: Vice
President, Real Estate
	  	 Name: Steven H. Holtzman
 Title:
President and CEO

 Exhibit A 

The Lease 
 (see attached)

 Exhibit B 

The Subleased Premises 
  

 
 The cross-hatched area represents an approximate depiction of the Subleased Premises. The furniture shown in
the depiction is for illustration purposes only. 

 Exhibit C 

Gross Rent Schedule 
  

																	
	 Period
	  	RSF	 	  	Gross Rent Per RSF	 	  	Annual Gross
Rent	 	  	Monthly
Gross Rent	 
	 Rent Commencement Date to January 31, 2020
	  	 	16,940	 	  	$	69.50	 	  	$	1,177,330.00	 	  	$	98,110.83	 
	 February 1, 2020 to January 31, 2021
	  	 	16,940	 	  	$	70.50	 	  	$	1,194,270.00	 	  	$	99,522.50	 
	 February 1, 2021 to January 31, 2022
	  	 	16,940	 	  	$	71.50	 	  	$	1,211,210.00	 	  	$	100,934.17	 
	 February 1, 2022 to January 31, 2023
	  	 	16,940	 	  	$	72.50	 	  	$	1,228,150.00	 	  	$	102,345.83	 
	 February 1, 2023 to January 31, 2024
	  	 	16,940	 	  	$	73.50	 	  	$	1,245,090.00	 	  	$	103,757.50	 
	 February 1, 2024 to January 31, 2025
	  	 	16,940	 	  	$	74.50	 	  	$	1,262,030.00	 	  	$	105,169.17	 
	 February 1, 2025 to January 31, 2026
	  	 	16,940	 	  	$	75.50	 	  	$	1,278,970.00	 	  	$	106,580.83	 
	 February 1, 2026 to January 31, 2027
	  	 	16,940	 	  	$	76.50	 	  	$	1,295,910.00	 	  	$	107,992.50	 

 Exhibit D 

Direct Deposit Instructions 

 Exhibit E 

The Non-Disturbance and Attornment Agreement 

(see attached) 

 Exhibit F 

Furniture Inventory 
 Date:
                                         
            
 This Furniture Inventory is being provided pursuant to that certain Sublease
Agreement dated as of                                     
(the “Sublease”) by and between United HealthCare Services, Inc., a Minnesota corporation (“Sublandlord”), and Decibel Therapeutics, Inc., a Delaware corporation (“Subtenant”). 

The parties to the Sublease desire to confirm that the following shall be the Furniture (as such term is defined in Section 28 of the Sublease): 

 

			
		
	  
	  	
		
	  
	  	
		
	  
	  	
		
	  
	  	
		
	  
	  	
		
	  
	  	
		
	  
	  	
		
	  
	  	
		
	  
	  	

 [SIGNATURE PAGE FOLLOWS] 

 IN WITNESS WHEREOF, Sublandlord and Subtenant have executed this Furniture Inventory as of the day and year
first above written. 
  

									
	SUBLANDLORD	 	                            	  	SUBTENANT
			
	 UNITED HEALTHCARE SERVICES, INC., 

a Minnesota corporation
	 		  	 DECIBEL THERAPEUTICS, INC., 

a Delaware corporation

									
					
	By:	 	  
	 	                            	  	By:	 	  

	Name:	 	  
	 	                            	  	Name:	 	  

	Title:	 	  
	 	                            	  	Title:

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