Document:

Restructuring Support Agreement

 Exhibit 10.1 
 RESTRUCTURING SUPPORT AGREEMENT 
 This RESTRUCTURING SUPPORT AGREEMENT (this
“Agreement”), dated as of September 11, 2009, is made by and among (i) Triple Crown Media, Inc. (the “Parent”) on behalf of itself and each of its subsidiaries (collectively, the
“Debtors”): (a) Triple Crown Media, LLC (“TCM”), (b) BR Acquisition Corp., (c) BR Holding, Inc., (d) Datasouth Computer Corporation, (e) Gray Publishing, LLC, and (f) Capital Sports
Properties, Inc; and (ii) the undersigned Supporting Second Lien Lenders (as defined below) (collectively with the Debtors, the “Parties” and each, a “Party”). 
 RECITALS 
 WHEREAS, the Debtors
are indebted to certain lenders (the “Second Lien Lenders”) on account of loan and advances (collectively, the “Second Lien Loans”) made under the Second Lien Senior Secured Credit Agreement, dated as of
December 30, 2005 (as amended, supplemented, amended and restated, or otherwise modified from time to time, the “Second Lien Credit Agreement”), by and among TCM, as Borrower; the Parent and each of the subsidiary guarantors
party thereto, as Guarantors; the Second Lien Lenders; and the Agent, as successor administrative and collateral agent; 
 WHEREAS,
the Parties have engaged in good faith negotiations with the objective of reaching an agreement with respect to the restructuring and recapitalization of the Debtors (the “Restructuring”); 
 WHEREAS, it is anticipated that the Restructuring will be implemented through a plan of reorganization of the Debtors pursuant to chapter 11 of
title 11 of the United States Code, 11 U.S.C. §§ 101, et seq. (the “Bankruptcy Code”), which plan shall contain, in all material respects, the same terms and conditions set forth in the proposed plan, attached as
Exhibit A hereto and incorporated herein by reference (the “Proposed Plan”); 
 WHEREAS, pursuant to the
Restructuring and Proposed Plan, the Debtors shall issue Second Lien Senior Secured Notes to the Second Lien Lenders on the terms and conditions set forth in the note term sheet, attached as Exhibit B hereto and incorporated herein by
reference (the “Note Term Sheet”); and 
 WHEREAS, this Agreement, the Proposed Plan, and the Note Term Sheet set
forth the agreement among the Parties concerning their commitment, subject to the terms and conditions of this Agreement, the Proposed Plan, and the Note Term Sheet, to implement the Restructuring. 
 NOW, THEREFORE, for valuable consideration, the receipt and sufficiency of which is hereby acknowledged, and subject to the fulfillment of the
terms and conditions set forth below, the Parties agree as follows: 
 1.        Definitions. The following
terms shall have the following definitions: 
 “Affiliate” means, with respect to any Person, any other Person which
directly or indirectly controls, is under common control with, or is controlled by, such Person. As used in 

 
this definition, “control” (including, with its correlative meanings, “controlled by” and “under common control
with”) shall mean, with respect to any Person, the possession, directly or indirectly, of power to direct or cause the direction of management or policies (whether through ownership of securities or partnership or other ownership interests,
by contract or otherwise) of such Person. 
 “Agreement” has the meaning given to such term in the preamble. 
 “Automatic Termination Event” has the meaning given to such term in Section 5. 
 “Ballot” means any ballot (including any beneficial ballot) distributed with the Disclosure Statement for purposes of voting on the
Plan. 
 “Bankruptcy Code” has the meaning given to such term in the recitals. 
 “Business Day” means any day other than a Saturday, Sunday and any day that is a legal holiday or a day on which banking institutions in
New York, New York are authorized by law or other governmental action to close. 
 “Bankruptcy Court” means the United
States Bankruptcy Court for the District of Delaware. 
 “Cash Collateral Order” means an interim or final order entered by
the Bankruptcy Court, authorizing the Debtors to use cash collateral (as such term is defined in section 363 of the Bankruptcy Code) and granting adequate protection to the Agent, in form and substance acceptable to the Agent and the Required
Supporting Second Lien Lenders in the sole discretion of each. 
 “Chapter 11 Cases” means the voluntary cases to be
commenced by each of the Debtors under chapter 11 of the Bankruptcy Code with the Bankruptcy Court. 
 “Corporate Governance
Documents” means the following corporate governance documents, as applicable: the (i) articles of incorporation or certificate of formation, (ii) bylaws, (iii) shareholder agreement or limited liability company operating
agreements, and (iv) registration rights agreement. 
 “Confirmation Order” means the order entered by the Bankruptcy
Court, confirming the Plan, including all exhibits, supplements, appendices, and related documents thereto, each in form and substance acceptable to the Agent and the Required Supporting Second Lien Lenders in the sole discretion of each.

 “Debtor Termination Event” has the meaning given to such term in Section 6. 
 “Disclosure Statement” means the disclosure statement in respect of the Plan, which shall be in form and substance acceptable to the
Agent and the Required Supporting Second Lien Lenders in the sole discretion of each. 
  

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 “Disclosure Statement Order” means the order entered by the Bankruptcy Court, approving
the Disclosure Statement, including all exhibits, supplements, appendices, and related documents thereto, for purposes of soliciting votes on the Plan, each in form and substance acceptable to the Agent and the Required Supporting Second Lien
Lenders in the sole discretion of each. 
 “Effective Date” means the date on which the Plan becomes effective. 

“Note Term Sheet” has the meaning given to such term in the recitals. 
 “Outside Date” means January 4, 2010, unless such date is extended by written agreement of the Parties. 
 “Party” and “Parties” have the meaning given to such terms in the preamble. 
 “Person” means an individual, a partnership, a joint venture, a limited liability company, a corporation, a trust, an unincorporated
organization, a group, or any other legal entity or association. 
 “Petition Date” means the date on which the Chapter 11
Cases of the Debtors are commenced in the Bankruptcy Court, which date shall be no later than September 14, 2009. 
 “Plan” means the (i) Proposed Plan or (ii) a plan of reorganization in respect of the Chapter 11 Cases, which contains all of the material terms and conditions set forth in the Proposed Plan and is in form and
substance acceptable to the Agent and the Required Supporting Second Lien Lenders in the sole discretion of each. 
 “Plan
Documents” means the Plan, the Solicitation Materials, the Disclosure Statement Order, the Confirmation Order, and any other documents filed with the Bankruptcy Court by the Debtors (or at the Debtors’ direction) that are necessary to
implement the Plan, including any appendices, amendments, modifications, supplements, exhibits, or schedules relating to any of the foregoing, including, without limitation, any: (a) term sheet, commitment letter, or operative document for any
proposed exit financing facility; (b) documents identifying the members of the board of directors of any Reorganized Debtor and compensation to be provided to any “insider” (as such term is defined in section 101 of the Bankruptcy
Code) to be employed or retained by any Reorganized Debtor; (c) list of material executory contracts and unexpired leases to be assumed, assumed and assigned, or rejected; (d) list of any material retained causes of action;
(e) Corporate Governance Document for any Reorganized Debtor; and (f) liquidating or distribution trust agreement; provided, however, that each of the foregoing documents shall be in form and substance acceptable to the Agent
and the Required Supporting Second Lien Lenders in the sole discretion of each. 
 “Proposed Plan” has the meaning given to
such term in the recitals. 
 “Restructuring” has the meaning given to such term in the recitals. 
  

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 “Restructuring Documents” has the meaning given to such term in Section 13.

 “Required Supporting Second Lien Lenders” means the Supporting Second Lien Lenders holding more than 67% of the aggregate
principal amount of the Second Lien Loans held by all of the Supporting Second Lien Lenders. 
 “Reorganized Debtors” means
the Debtors, in each case, or any successor thereto (by merger, consolidation or otherwise), on or after the Effective Date. 
 “Second Lien Claims” means any claim (as such term is defined in section 101 of the Bankruptcy Code) against any Debtor arising under the Second Lien Credit Documents. 
 “Second Lien Credit Agreement” has the meaning given to such term in the recitals. 
 “Second Lien Credit Documents” means the Second Lien Credit Agreement and the other Loan Documents (as defined in the Second Lien Credit
Agreement). 
 “Second Lien Lenders” has the meaning given to such term in the recitals. 
 “Second Lien Loans” has the meaning given to such term in the recitals. 
 “Solicitation Materials” means the Ballots, Disclosure Statement, and other solicitation materials distributed in respect of the Plan,
as approved by the Bankruptcy Court pursuant to section 1125 and 1126(b) of the Bankruptcy Code. 
 “Supporting Second Lien
Lenders” means the undersigned Second Lien Lenders and any holder of the Second Lien Loans who, after the date of this Agreement, executes a counterpart to this Agreement or takes the actions required of a transferee in accordance with
Section 10. 
 “Termination Event” has the meaning given to such terms in Section 5. 
 “Transfer” has the meaning given to such term in Section 10. 
 2.        Supporting Second Lien Lenders’ Consent. Unless otherwise specified herein, where this Agreement provides for the action, consent, or approval of the
Supporting Second Lien Lenders, such action, consent, or approval shall be upon the agreement of the Required Supporting Second Lien Lenders. 
 3.        Commitment of Supporting Second Lien Lenders. Subject to the terms and conditions of this Agreement, the Proposed Plan, and the Note Term Sheet, each Supporting Second Lien Lender
(severally and not jointly) agrees: 
  

	 	(a)	 so long as its vote has been properly solicited pursuant to sections 1125 and 1126 of the Bankruptcy Code, to (i) timely vote (or cause to be voted) all Second
Lien Claims beneficially owned by such Supporting Second Lien Lender, or for which it serves as the nominee, investment manager, or advisor for the beneficial holders 

  

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thereof, in favor of the Plan, in accordance with the applicable procedures set forth in the Solicitation Materials, and (ii) to the extent such
election is available, not elect on its Ballot to preserve any Second Lien Claims that may be affected by any releases provided for under the Plan; 

  

	 	(b)	not to withdraw or revoke its vote with respect to the Plan; and 

  

	 	(c)	not to (i) object to the Plan, the Disclosure Statement, the consummation of the Plan, or any efforts to solicit acceptances for, confirm, and implement the Plan;
(ii) commence any legal proceedings (x) that would delay or prevent the approval, confirmation, or consummation of the Plan, Disclosure Statement, or transactions outlined therein or in the Note Term Sheet, or (y) to oppose any action
necessary to effectuate the Plan or any other Plan Document, so long as the Plan and all other Plan Documents contain terms and conditions that conform in all material respects to the Proposed Plan and Note Term Sheet, subject to the rights of the
Supporting Second Lien Lenders under this Section 3; (iii) vote for, consent to, support, or participate in the formulation of any other restructuring, plan of reorganization, proposal or offer of dissolution, winding up,
liquidation, reorganization, merger, transaction, sale, or disposition in respect of the Debtors (or any of their assets or stock), other than the Plan or as set forth in the Plan or Note Term Sheet; or (iv) solicit, encourage, or direct any
person or entity, including, without limitation, the Agent, to undertake any action set forth in clauses (i) through (iii) of this subsection (c). 

 Notwithstanding anything herein to the contrary, no Supporting Second Lien Lender shall be obligated to vote in favor of the Plan, and each may, acting individually and of its own accord, withdraw or revoke its
consent or vote with respect to the Plan upon the (x) termination of this Agreement in accordance with its terms; or (y) withdrawal, amendment, or modification of (or the filing of any pleading by the Debtors seeking to withdraw, amend, or
modify) the Plan, Disclosure Statement, or other Plan Document in a manner that is materially inconsistent with this Agreement, the Proposed Plan, or the Note Term Sheet and adverse to such Supporting Second Lien Lender without such Supporting
Second Lien Lender’s prior written consent. 
 4.        Commitment of the Debtors. Subject to their
fiduciary duties as debtors in possession, the Debtors agree to use commercially reasonable efforts to (i) support and take any necessary and appropriate actions (including obtaining any required regulatory and third party approvals and orders
of the Bankruptcy Court) to further the Restructuring, the Plan, and all transactions contemplated under the Plan and Note Term Sheet; (ii) complete the Restructuring, the Plan, and all transactions contemplated under the Plan and Note Term
Sheet within the time-frame outlined in Section 5; and (iii) take no actions inconsistent with this Agreement, the Plan, the Note Term Sheet or the confirmation and consummation of the Plan. Notwithstanding anything to the contrary
herein, the Debtors shall not solicit acceptances of the Plan from any Supporting Second Lien Lender until such Supporting Second Lien Lender has been provided with copies of a Disclosure Statement approved by the Bankruptcy Court. 
  

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 5.        Termination by Supporting Second Lien Lenders. Unless otherwise
consented to in writing by the Required Supporting Second Lien Lenders, this Agreement may be terminated upon the occurrence of any of the following events (each, a “Termination Event”): 
  

	 	(a)	the Debtors fail to commence the Chapter 11 Cases on or before 11:59 P.M. (prevailing Eastern time) on the Petition Date; 

  

	 	(b)	an interim Cash Collateral Order has not been entered by the Bankruptcy Court on or before 11:59 P.M. (prevailing Eastern time) on the date that is fifteen (15) days after the
Petition Date; 

  

	 	(c)	a final Cash Collateral Order has not been entered by the Bankruptcy Court on or before 11:59 P.M. (prevailing Eastern time) on the date that is forty (40) days after the
Petition Date; 

  

	 	(d)	the termination of any Cash Collateral Order in accordance with its terms; 

  

	 	(e)	the Debtors fail to file the Plan and Disclosure Statement on or before 11:59 P.M. (prevailing Eastern time) on the date that is fifteen (15) days after the Petition Date;

  

	 	(f)	the Disclosure Statement Order has not been entered by the Bankruptcy Court on or before 11:59 P.M. (prevailing Eastern time) on the date that is forty-five (45) days after the
Petition Date; 

  

	 	(g)	the Confirmation Order has not have been entered by the Bankruptcy Court on or before 11:59 P.M. (prevailing Eastern time) on the date that is ninety-one (91) days after the
Petition Date; 

  

	 	(h)	the Effective Date has not occurred on or before 11:59 P.M. (prevailing Eastern time) on the date that is one hundred and one (101) days after the Petition Date;

  

	 	(i)	the occurrence of the Effective Date; 

  

	 	(j)	the occurrence of the Outside Date; 

  

	 	(k)	the filing of any plan of reorganization or disclosure statement that is materially inconsistent with this Agreement, the Proposed Plan, or the Note Term Sheet and not acceptable to
the Agent and the Required Supporting Second Lien Lenders in the sole discretion of each; 

  

	 	(l)	the withdrawal, amendment, modification of (or the filing of a pleading by the Debtors seeking to withdraw, amend, or modify) the Plan, the Disclosure Statement, or other Plan
Document in a manner that is materially inconsistent with this Agreement, Proposed Plan, or the Note Term Sheet and not acceptable to the Agent and the Required Supporting Second Lien Lenders in the sole discretion of each; 

 

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	 	(m)	the filing of any pleading by the Debtors seeking to (i) voluntarily dismiss any Chapter 11 Case, (ii) convert any Chapter 11 Case to chapter 7 of the Bankruptcy Code, or
(iii) appoint a trustee, an examiner, or a similar fiduciary with expanded powers pursuant to section 1104 of the Bankruptcy Code in any Chapter 11 Case; 

  

	 	(n)	the entry of an order by the Bankruptcy Court (i) dismissing any Chapter 11 Case, (ii) converting any Chapter 11 Case to chapter 7 of the Bankruptcy Code, or
(iii) appointing a trustee, an examiner, or a similar fiduciary with expanded powers pursuant to section 1104 of the Bankruptcy Code in any Chapter 11 Case; 

  

	 	(o)	the issuance of an order by any court of competent jurisdiction or other governmental or regulatory authority that prohibits or restricts the Restructuring, the Plan, or the
transactions contemplated under the Plan and the Note Term Sheet in a manner that cannot be reasonably remedied by the Debtors; 

  

	 	(p)	the filing of any pleading or commencement of any action by the Debtors (or the joinder of the Debtors in or support by the Debtors of any such pleading or action) seeking to prime
or challenge the validity, enforceability, perfection, or priority of any lien or security interest securing the Second Lien Claims under the Second Lien Credit Documents; 

  

	 	(q)	the filing of any pleading or commencement of any action by the Debtors (or the joinder of the Debtors in or support by the Debtors of any such pleading or action) against the Agent
or any Supporting Second Lien Lender with respect to the Second Lien Claims or Second Lien Credit Documents; 

  

	 	(r)	the public announcement by the Debtors of their intention not to support the Plan; or 

  

	 	(s)	the occurrence of any material breach of this Agreement by any Debtor. 

 Upon the occurrence of a Termination Event under subsections (d), (i), (n), and (o) (each, an “Automatic Termination Event”), this Agreement shall automatically terminate without further action.

 Upon the occurrence and during the continuation of a Termination Event that is not an Automatic Termination Event, this Agreement shall
terminate upon the expiration of five (5) Business Days after the Agent provides written notice of such Termination Event to the Debtors, unless the Debtors cure such Termination Event prior to the expiration of such period. 
 6.        Termination by the Debtors. The Debtors may terminate this Agreement as to any Supporting Second Lien Lender
upon five (5) Business Days’ prior written notice to the Agent upon any material breach of this Agreement by such Supporting Second Lien Lender (a “Debtor Termination Event”), unless such Supporting Second Lien Lender
cures such Debtor Termination Event prior to the expiration of 
 such period. Any termination of this Agreement 

  

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arising out of a Debtor Termination Event shall apply only to the individual Supporting Second Lien Lender, and this Agreement shall remain in full force and
effect with respect to the remaining Parties. 
 7.        Waiver of Automatic Stay. The Parties hereby
(i) waive any requirement to lift or modify the automatic stay under section 362 of the Bankruptcy Code in the Chapter 11 Cases in connection with any notice of termination provided hereunder and (ii) agree not to object to any
non-breaching Party seeking to lift such automatic stay in connection with any such notice. 
 8.        Effect of
Termination. Upon the termination of this Agreement, all obligations hereunder shall terminate and be of no further force and effect; provided, however, that any claim for breach of this Agreement shall survive termination and all
rights and remedies with respect to such claims shall not be prejudiced in any way; provided, further, that the breach of this Agreement by one or more Parties shall not create any rights or remedies against any non-breaching Party
unless such non-breaching Party has participated in or aided and abetted the breach by a breaching Party or Parties; provided, further, that the confidentiality agreements referenced in Section 16 hereof shall survive termination
of this Agreement. Except as set forth in this Section 8, upon such termination, any obligations of the non-breaching Parties set forth in this Agreement shall be null and void ab initio and all claims, causes of actions,
remedies, defenses, setoffs, rights, or other benefits of such non-breaching Parties shall be fully preserved without any estoppel, evidentiary, or other effect of any kind or nature whatsoever. 
 9.        Appearances. Notwithstanding anything herein to the contrary, any Party may appear as a party-in-interest in any
matter to be adjudicated in the Chapter 11 Cases; provided, however, that such appearance and the positions advocated in connection therewith are not barred by this Agreement. 
 10.      Transfer of Second Lien Claims. 
  

	 	(a)	Each Supporting Second Lien Lender agrees that it shall not sell, assign, transfer, convey, pledge, hypothecate, or otherwise dispose of, directly or indirectly (each, a
“Transfer”), any of its Second Lien Claims (or any voting or other rights associated therewith), unless the transferee: (a) agrees in writing to be bound by this Agreement, the Proposed Plan, and the Note Term Sheet and to
assume the rights and obligations of the transferring Supporting Second Lien Lender thereunder; and (b) delivers such agreement to the Debtors and the Agent within two (2) Business Days after the relevant transfer. Upon the Transfer and
the completion of the procedures in this Section 10(a), such transferee shall become a Supporting Second Lien Lender hereunder. 

  

	 	(b)	The Debtors shall promptly acknowledge such Transfer in writing and deliver such acknowledgement to the transferee and the Agent. By acknowledging such Transfer, the Debtors agree
that the obligations of the Debtors to the transferor shall be deemed to be obligations to the transferee. 

  

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	 	(c)	Any Transfer of any Second Lien Claim by a Supporting Second Lien Lender that fails to comply with the procedures set forth in Section 10(a) shall be deemed void ab
initio. 

  

	 	(d)	This Agreement shall in no way be construed to preclude any Supporting Second Lien Lender from acquiring additional Second Lien Claims; provided, however, that such
additional Second Lien Claims shall automatically be deemed subject to the terms and conditions of this Agreement; provided, further that the Supporting Second Lien Lender shall provide written notice to the other Parties within five
(5) Business Days of the acquisition of any additional Second Lien Claims. 

 11.    Effectiveness. This
Agreement shall become effective and binding upon each of the undersigned Parties as of the date when (i) each Party has executed and delivered signed copies of this Agreement to each other Party; and (ii) the Agent and counsel to the
Agent have received all outstanding fees and expenses through the date of this Agreement and a single $100,000 retainer for counsel to the Agent, which, to the extent not applicable to fees and expenses prior to the Petition Date, shall be applied
to fees and expenses incurred by such counsel and payable in accordance with any Cash Collateral Order entered by the Bankruptcy Court. 
 12.
    No Deemed Solicitation. This Agreement and the Proposed Plan are not and shall not be deemed to be a solicitation of votes for the acceptance of the Plan (or any other plan of reorganization) for the purposes of
sections 1125 and 1126 of the Bankruptcy Code or otherwise. 
 13.    Cooperation. 
  

	 	(a)	Each Party shall use commercially reasonable efforts to negotiate in good faith all definitive documentation to which it will be a party, as necessary to consummate the
Restructuring and the transactions contemplated by the Proposed Plan and Note Term Sheet, and in all respects consistent with the Proposed Plan and Note Term Sheet. 

  

	 	(b)	The Debtors shall provide draft copies of any Plan Document or other motion, pleading, proposed order, press release, public statement, or document that relates or refers to the
Restructuring, the Proposed Plan, the Note Term Sheet, or any of the transactions or documentation contemplated thereby (each, a “Restructuring Document”) to the Agent or its representatives (including counsel) for review and
comment within a reasonable time prior to making public or filing such Restructuring Document with the Bankruptcy Court. 

  

	 	(c)	The Debtors shall refrain from making public or filing any Restructuring Document with the Bankruptcy Court without the prior consent of the Agent or its representatives (including
counsel), which consent shall not be unreasonably withheld, conditioned, or delayed. 

 14.    Claim Resolution
Matters. Prior to the entry of the Confirmation Order, the Debtors may enter into agreements with holders of claims (as such term is defined in the Bankruptcy Code) (other than the Supporting Second Lien Lenders) relating to the allowance,
estimation, validity, extent, or priority of such claims, or the treatment and classification of such claims under the 

  

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Plan; provided, however, that the Debtors shall provide the Agent with at least three (3) Business Days’ prior written notice of any
pleading seeking authority for the Debtors to enter into any such agreement; provided, further, that if the Agent has not notified the Debtors of its objection or response to such pleading on or before the expiration of such period,
the Debtors shall be authorized to proceed with such pleading. Notwithstanding the foregoing, the Debtors shall not be required to provide the Agent with advance notice with respect to the payment of (i) any trade payables and employee benefits
and obligations which arise in the ordinary course of the Debtors’ business, and (ii) claims which the Debtors are authorized to resolve or pay pursuant to any order of the Bankruptcy Court. 
 15.    Business Continuance. Unless otherwise consented to in writing by the Required Supporting Second Lien Lenders, and except for changes
resulting from or relating to the filing of the Chapter 11 Cases or imposed by the Bankruptcy Court, the Debtors agree that, between the date of this Agreement and the Effective Date, the Debtors shall (i) operate their businesses in the
ordinary course in a manner consistent with past practice in all material respects; (ii) use commercially reasonable efforts to preserve relationships with current customers, distributors, suppliers, vendors, and others having business dealings
with the Debtors, including the performance of all material obligations under any executory contracts which have not been rejected; (ii) maintain and insure their physical assets, properties, and facilities in their current condition as of the
date hereof (ordinary wear and tear excepted); and (iii) maintain the Debtors’ books and records on a basis consistent with prior practice, including historical billing and collection practices. 
 16.    Access. The Debtors agree to respond to reasonable requests from the Agent and Supporting Second Lien Lenders or their representatives
(including counsel) regarding the Debtors’ business, Chapter 11 Cases, general status of ongoing operations, and operating results and provide access to the Debtors’ offices, properties, personnel, and books and records; provided,
however, that any such request and or provision of access does not interfere unreasonably with the normal business operations of the Debtors; provided, further, that the Agent and Supporting Second Lien Lenders execute
confidentially agreements reasonably acceptable to the Debtors and their counsel. 
 17.    Representations by Parties. Each Party
represents to each other Party that the following statements are true, correct, and complete, as of the date of this Agreement: 
  

	 	(a)	Corporate Power and Authority. Such Party is duly organized, validly existing, and in good standing under the laws of the jurisdiction of its organization, and has all
requisite corporate, partnership, or limited liability company power and authority to enter into this Agreement and to carry out the transactions contemplated by, and perform its respective obligations under, this Agreement.

  

	 	(b)	 No Conflicts. The execution, delivery, and performance of this Agreement by such Party does not and shall not (i) conflict with or result in any breach
of the charter or by-laws or similar organizational document of such Party, (ii) result in a violation or breach of, or constitute (with due notice or lapse of time or both) a default (or give rise to any right of termination, cancellation, or
acceleration) under any material note, bond, mortgage, indenture, license, contract, agreement, 

  

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or other instrument or obligation to which such Party or any of its subsidiaries is a party or by which any of them or any of their properties or assets may
be bound; or (iii) violate any order, injunction, statute, rule, or regulation applicable to such Party, any of its subsidiaries, or any of their properties or assets. 

  

	 	(c)	Governmental Consents. The execution, delivery, and performance by such Party of this Agreement does not and shall not require any registration or filing with, consent, or
approval of, or notice to, or other action to, with, or by any federal, state, or other governmental authority or regulatory body, except such filing as may be necessary for disclosure to the Securities and Exchange Commission, pursuant to state
securities or “blue sky” laws, or to obtain the approval by the Bankruptcy Court of the Debtors’ authority to enter into and implement this Agreement. 

  

	 	(d)	Binding Obligations. Subject to the provisions of sections 1125 and 1126 of the Bankruptcy Code, and assuming the due execution and delivery of this Agreement by all Parties,
this Agreement is the legally valid and binding obligation of such Party, enforceable against it in accordance with its terms, except as enforcement may be limited by bankruptcy, insolvency, reorganization, moratorium, or other similar laws, either
foreign or domestic, or by equitable principles relating to or limiting creditors’ rights generally. 

 18.    Ownership of Second Lien Loans. Each Supporting Second Lien Lender represents and warrants (severally and not jointly) that: 
  

	 	(a)	as of the date of this Agreement, it is the beneficial owner of the principal amount of the Second Lien Loans, or is the nominee, investment manager, or advisor for beneficial
holders of the Second Lien Loans, as such Supporting Second Lien Lender has indicated on Exhibit C hereto; provided, however, that Exhibit C shall only be disclosed to the Debtors, their legal counsel, and any financial
or restructuring advisors retained by the Debtors upon approval by the Bankruptcy Court; and 

  

	 	b)	other than pursuant to this Agreement, such Second Lien Loans are free and clear of any pledge, lien, security interest, charge, claim, equity, option, proxy, voting restriction,
right of first refusal, or other limitation on disposition or encumbrances of any kind, that might adversely affect in any way such Supporting Second Lien Lender’s performance of its obligations contained in this Agreement at the time such
obligations are required to be performed. 

 19.    Public Disclosure. The Debtors shall not (a) use the name
of any Supporting Second Lien Lender in any press release without such Supporting Second Lien Lender’s prior written consent or (b) disclose to any Person (other than legal and financial advisors to the Debtors) the principal amount or
percentage of any Second Lien Loans held by any Supporting Second Lien Lender or any Affiliate; provided, however, that the Debtors shall be permitted to disclose the aggregate principal amount of and aggregate percentage of Second
Lien Loans held by the Supporting Second Lien Lenders; provided, further, that the Debtors may disclose the execution 

  

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and contents of this Agreement in the Plan, Disclosure Statement, other Plan Documents, and any filings by the Debtors with the Bankruptcy Court or the
Securities and Exchange Commission, or as required by applicable law. 
 20.    No Waiver of Participation; Reservation of Rights.
Except as expressly provided in this Agreement and in any amendment among the Parties, nothing herein is intended to, or does, in any manner, waive, limit, impair, or restrict the ability of each Party to protect and preserve its rights, remedies,
and interests, including, without limitation, its claims against any other Party (or its respective Affiliates) or its full participation in the Chapter 11 Cases. If the transactions contemplated by this Agreement, the Plan, and the Note Term Sheet
are not consummated, or if this Agreement is terminated for any reason, the Parties fully reserve any and all of their rights, remedies, defenses, and privileges. 
 21.    No Admissions. This Agreement shall in no event be construed as or be deemed to be evidence of an admission or concession on the part of any Party of any claim, fault, liability or damages whatsoever.
Without limiting the foregoing, pursuant to Federal Rule of Evidence 408 and any other applicable rules of evidence, this Agreement and all negotiations relating hereto will not be admissible into evidence in any proceeding, other than a proceeding
to enforce the terms of this Agreement. Each Party denies any and all wrongdoing or liability of any kind and does not concede any infirmity in the claims or defenses which it has asserted or could assert. 
 22.    Fiduciary Duties. Notwithstanding anything to the contrary herein, nothing in this Agreement shall require any Party or any of its
directors or officers (in such person’s capacity as a director or officer) to take any action, or refrain from taking any action, to the extent that taking such action, or refraining from taking such action, would be inconsistent with such
person’s fiduciary obligations under applicable law. 
 23.    Representation by Counsel. Each Party acknowledges that it has
been represented by counsel (or had the opportunity to and waived its right to do so) in connection with this Agreement and the transactions contemplated by this Agreement. Accordingly, any rule of law or any legal decision that would provide any
Party with a defense to the enforcement of the terms of this Agreement against such Party based on lack of legal counsel shall have no application and is expressly waived. 
 24.    Independent Due Diligence and Decision-Making. Each Supporting Second Lien Lender confirms that its decision to execute this Agreement has been based upon its independent
investigation of the operations, businesses, financial, and other conditions and prospects of the Debtors. 
 25.    Relationship
Among Parties. Notwithstanding anything herein to the contrary, the duties and obligations of the Supporting Second Lien Lenders under this Agreement shall be several, not joint, and no prior history, pattern or practice of sharing confidences
among or between Parties shall in any way affect or negate this understanding and agreement. No Party shall have, solely by reason of this Agreement, a fiduciary relationship in respect of any other Party, person, or entity, and nothing herein,
expressed or implied, is intended to or shall be so construed as to impose upon any Party any obligations in respect of this Agreement except as expressly set forth herein. 
  

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 26.    Specific Performance. It is understood and agreed by the Parties that monetary damages
would be an insufficient remedy for any breach of this Agreement by any Party and each non-breaching Party shall be entitled to specific performance and injunctive or other equitable relief as a remedy for such breach; provided,
however, that each Party agrees to waive any requirement for the securing or posting of a bond in connection with such remedy. In no event shall any Party be liable for any special, indirect, incidental, punitive, or consequential damages of
any kind or nature. 
 27.    Tax Matters. The Debtors shall not, without the prior written consent of the Agent: (i) cause
(or cause another party to make) any new or change a current “check the box” election under Treasury Regulations § 301.7701-3 with respect to the Debtors, or (ii) merge, consolidate, or liquidate, if any of the actions specified
in clauses (i) or (ii) have material adverse tax consequences for the Debtors or the Supporting Second Lien Lenders. 
 28.    Notices. All notices, requests, and other communications shall be in writing and be deemed to have been duly given only if delivered by hand, email, courier, facsimile transmission, or mail (first class
postage prepaid) to the parties at the following addresses, emails, or facsimile numbers: 
 If to the Debtors: 
 Triple Crown Media, Inc. 
 725A Old Norcross Road 
 Lawrenceville, GA 30045 
 Attn: Mark Meikle 

			
	Telephone:	 	(859) 226-4376
	Email:	 	Mark.Meikle@triplecrownmedia.com

 With a copy to: 
 Dinsmore & Shohl LLP 
 Lexington Financial Center 
 250 West Main Street, Suite 1400 
 Lexington, KY 40507 
 Attn: Joseph H. Terry, Esq. 

			
	Telephone:	 	(859) 425-1000
	Facsimile:	 	(859) 425-1099
	Email:	 	terry@dinslaw.com

 If to the Agent or the Supporting Second Lien Lenders: 
 Wilmington Trust FSB 
 246 Goose Lane, Suite 105 
 Guilford, CT 06437 
 Attn: Joseph P. O’Donnell 

			
	Telephone:	 	(203) 453-4130
	Facsimile:	 	(203) 453-1183

  

 - 13 - 

			
	E-mail:	 	jodonnell@wilmingtontrust.com

 With a copy to: 
 Ropes & Gray LLP 
 1211 Avenue of the Americas 
 New York, NY 10036-8704 
 Attn: Mark R. Somerstein, Esq. 

			
	Telephone:	 	(212) 841-8814
	Facsimile:	 	(212) 596-9090
	Email:	 	mark.somerstein@ropesgray.com

 29.    Amendments or Waivers. Except as otherwise provided herein, this Agreement may
not be modified, amended, waived, or supplemented without the prior written consent of the Debtors, the Agent, and the Required Supporting Second Lien Lenders; provided, however, that the effectiveness of any modification, amendment,
waiver, or supplement that adversely impacts the economic treatment or rights of any Supporting Second Lien Lender hereunder shall also require the prior written consent of such affected Supporting Second Lien Lender. No waiver of any provisions of
this Agreement shall be deemed or constitute a waiver of any other provisions of this Agreement, whether or not similar, or be deemed a continuing waiver (unless such waiver expressly provides otherwise). 
 30.    No Third-Party Beneficiaries. The terms and provisions of this Agreement, the Proposed Plan, and the Note Term Sheet are intended
solely for the benefit of the Parties hereto and their respective successors and permitted assigns, and it is not the intention of the Parties to confer third-party beneficiary rights upon any other Person. 
 31.    Successors. This Support Agreement is intended to bind the Parties and inure to the benefit of the Parties and their respective
successors, assigns, heirs, executors, administrators, and representatives; provided, however, that nothing contained in this Section 31 shall be deemed to permit any Transfer of any Second Lien Claims other than in accordance
with the terms of this Agreement. 
 32.    Governing Law. The Parties irrevocably waive all rights to trial by jury in any
jurisdiction in any action, suit, proceeding, or counterclaim (whether based in contract, tort, or otherwise) arising out of or relating to this Agreement or the transactions contemplated hereby. This Agreement shall be governed by, and construed in
accordance with, the laws of the State of New York, without regard to any conflicts of law provision which would require the application of the law of any other jurisdiction. By its execution and delivery of this Agreement, each Party irrevocably
and unconditionally agrees that any legal action, suit, or proceeding against it with respect to any matter arising under, arising out of, or in connection with this Agreement or for recognition or enforcement of any judgment rendered in any such
action, suit, or proceeding, may be brought in the United States District Court for the Southern District of New York, and by execution and delivery of this Agreement, each Party irrevocably accepts and submits itself to the exclusive jurisdiction
of such court, generally and unconditionally, with respect to any such action, suit, or proceeding. Notwithstanding the foregoing, upon the commencement of the 

  

 - 14 - 

 
Chapter 11 Cases, each Party agrees that the Bankruptcy Court shall have exclusive jurisdiction of all matters arising out of or in connection with this
Agreement. 
 33.    Entire Agreement. This Agreement, including the exhibits hereto, constitute the entire agreement of the
Parties and supersedes all other prior negotiations, agreements, and understandings, whether written or oral, among the Parties with respect to the subject matter of this Agreement. 
 34.    Interpretation. This Agreement is the product of negotiations of the Parties, and is to be interpreted in a neutral manner with respect to the enforcement or interpretation hereof.
Any presumption for or against any Party by reason of that Party having drafted or caused to be drafted this Agreement, or any portion hereof, shall not be effective with respect to the enforcement or interpretation hereof. In the event of any
inconsistency among the terms and conditions set forth in this Agreement, the Proposed Plan, and the Note Term Sheet, the terms and conditions in the Proposed Plan and Note Term Sheet shall control. 
 35.    Headings. The headings of the sections, paragraphs, and subsections of this Agreement are for convenience only and shall not affect the
interpretation hereof. 
 36.    Counterparts. This Agreement may be executed in one or more counterparts, each of which, when so
executed, shall be deemed an original and all of which shall constitute one and the same instrument. The counterparts may be delivered by facsimile transmission or by electronic mail in portable document format (.pdf). 
 [The remainder of this page has been intentionally left blank.] 
  

 - 15 - 

 IN WITNESS WHEREOF, each Party has caused this Agreement to be executed by its duly authorized
officer under seal as of the date first set forth above. 
 DEBTORS: 
  

			
	 TRIPLE CROWN MEDIA, LLC

		
	By:	 	 /s/ Mark Meikle

	Name:	 	Mark Meikle
	Title:	 	Executive Vice President and CFO
	
	 TRIPLE CROWN MEDIA, INC.,

		
	By:	 	 /s/ Mark Meikle

	Name:	 	Mark Meikle
	Title:	 	Executive Vice President and CFO
	
	 BR ACQUISITION CORP.,

		
	By:	 	 /s/ Mark Meikle

	Name:	 	Mark Meikle
	Title:	 	Executive Vice President and CFO
	
	 BR HOLDING, INC.,

		
	By:	 	 /s/ Mark Meikle

	Name:	 	Mark Meikle
	Title:	 	Executive Vice President and CFO
	
	 DATASOUTH COMPUTER CORPORATION,

		
	By:	 	 /s/ Mark Meikle

	Name:	 	Mark Meikle
	Title:	 	Executive Vice President and CFO

 [Signature Page to Restructuring Support Agreement] 

			
	GRAY PUBLISHING, LLC,
		
	By:	 	 /s/ Mark Meikle

	Name:	 	Mark Meikle
	Title:	 	Executive Vice President and CFO
	
	CAPITAL SPORTS PROPERTIES, INC.,
		
	By:	 	 /s/ Mark Meikle

	Name:	 	Mark Meikle
	Title:	 	Executive Vice President and CFO

 [Signature Page to Restructuring Support Agreement] 

			
	 SUPPORTING SECOND LIEN LENDERS:

	
	GPC LVIII, LLC
	By: GoldenTree Asset Management, LP
		
	By:	 	 /s/ Karen Weber

	Name:	 	Karen Weber
	Title:	 	Authorized Signatory
	
	GOLDENTREE 2004 TRUST
	By: GoldenTree Asset Management, LP
		
	By:	 	 /s/ Karen Weber

	Name:	 	Karen Weber
	Title:	 	Authorized Signatory
	
	 GOLDENTREE CAPITAL SOLUTIONS FUND FINANCING

	By: GoldenTree Asset Management, LP
		
	By:	 	 /s/ Karen Weber

	Name:	 	Karen Weber
	Title:	 	Authorized Signatory
	
	 GOLDENTREE CAPITAL SOLUTIONS OFFSHORE FUND FINANCING

	By: GoldenTree Asset Management, LP
		
	By:	 	 /s/ Karen Weber

	Name:	 	Karen Weber
	Title:	 	Authorized Signatory
	
	 GOLDENTREE CAPITAL OPPORTUNITIES, LP

	By: GoldenTree Asset Management, LP
		
	By:	 	 /s/ Karen Weber

	Name:	 	Karen Weber
	Title:	 	Authorized Signatory

 [Signature Page to Restructuring Support Agreement] 

			
	 GOLDENTREE MULTISTRATEGY FINANCING, LIMITED

	By: GoldenTree Asset Management, LP
		
	By:	 	 /s/ Karen Weber

	Name:	 	Karen Weber
	Title:	 	Authorized Signatory

 [Signature Page to Restructuring Support Agreement]Form of Indemnification Agreement

 Exhibit 10.19 
 INDEMNIFICATION AGREEMENT 
 This Agreement, made and entered into this
             day of             , 2009 (“Agreement”), by and between CombinatoRx, Incorporated, a Delaware corporation
(the “Company”), and              (“Indemnitee”): 
 WHEREAS,
it is reasonable, prudent and necessary for the Company to obligate itself to indemnify, and to advance expenses on behalf of, its directors to the fullest extent permitted by applicable law so that they will serve or continue to serve the Company
free from undue concern that they will not be so indemnified; and 
 WHEREAS, Indemnitee is willing to serve, continue to serve the Company
as a director and to take on additional service for or on its behalf on the condition that he be so indemnified; 
 NOW, THEREFORE, in
consideration of the premises and the covenants contained herein, the Company and Indemnitee do hereby covenant and agree as follows: 
  

	1.	Services by Indemnitee. Indemnitee agrees to serve as a director of the Company. Indemnitee may at any time and for any reason resign from such position (subject to any other
contractual obligation or any obligation imposed by operation of law). 

  

	2.	Indemnification—General. The Company shall indemnify, and advance Expenses (as hereinafter defined) to, Indemnitee (a) as provided in this Agreement and
(b) (subject to the provisions of this Agreement) to the fullest extent permitted by applicable law in effect on the date hereof and as amended from time to time. The rights of Indemnitee provided under the preceding sentence shall include, but
shall not be limited to, the rights set forth in the other Sections of this Agreement. 

  

	3.	Proceedings Other Than Proceedings by or in the Right of the Company. Indemnitee shall be entitled to the rights of indemnification provided in this Section 3 if, by
reason of Indemnitee’s Corporate Status (as hereinafter defined), Indemnitee is, or is threatened to be made, a party to or a participant in any threatened, pending or completed Proceeding (as hereinafter defined), other than a Proceeding by or
in the right of the Company. Pursuant to this Section 3, Indemnitee shall be indemnified against all Expenses, judgments, penalties, fines and amounts paid in settlement (including all interest, assessments and other charges paid or payable in
connection with or in respect of such Expenses, judgments, penalties, fines and amounts paid in settlement) actually and reasonably incurred by Indemnitee or on behalf of Indemnitee in connection with such Proceeding or any claim, issue or matter
therein, if Indemnitee acted in good faith and in a manner Indemnitee reasonably believed to be in or not opposed to the best interests of the Company and, with respect to any criminal Proceeding, had no reasonable cause to believe Indemnitee’s
conduct was unlawful. 

  

	4.	 Proceedings by or in the Right of the Company. Indemnitee shall be entitled to the rights of indemnification provided in this Section 4 if, by reason of
Indemnitee’s Corporate Status, Indemnitee is, or is threatened to be made, a party to or a participant in any threatened, pending or completed Proceeding brought by or in the right of the Company to procure a judgment in its favor. Pursuant to
this Section, Indemnitee shall be indemnified against all Expenses (including all interest, assessments and other charges paid or payable in connection with or in respect of 

  

 1 

	 	 
such Expenses) actually and reasonably incurred by Indemnitee or on behalf of Indemnitee in connection with such Proceeding if Indemnitee acted in good faith
and in a manner Indemnitee reasonably believed to be in or not opposed to the best interests of the Company; provided, however, that indemnification against such Expenses shall be made in respect of any claim, issue or matter in such
Proceeding as to which Indemnitee shall have been adjudged to be liable to the Company if and only to the extent that the Court of Chancery of the State of Delaware, or the court in which such Proceeding shall have been brought or is pending, shall
determine that such indemnification may be made. 

  

	5.	Partial Indemnification. Notwithstanding any other provision of this Agreement, to the extent that Indemnitee is, by reason of Indemnitee’s Corporate Status, a party to
(or a participant in) and is successful, on the merits or otherwise, in defense of any Proceeding, Indemnitee shall be indemnified against all Expenses actually and reasonably incurred by Indemnitee or on behalf of Indemnitee in connection
therewith. If Indemnitee is not wholly successful in defense of such Proceeding but is successful, on the merits or otherwise, as to one or more but less than all claims, issues or matters in such Proceeding, the Company shall indemnify Indemnitee
against all Expenses actually and reasonably incurred by Indemnitee or on behalf of Indemnitee in connection with each successfully resolved claim, issue or matter. For purposes of this Section and without limitation, the termination of any claim,
issue or matter in such a Proceeding by dismissal, with or without prejudice, shall be deemed to be a successful result as to such claim, issue or matter. If Indemnitee is entitled under any provision of this agreement to indemnification by the
Company for some or a portion of the Expenses, judgments, penalties, fines and amounts paid in settlement (including all interest, assessments and other charges paid or payable in connection with or in respect of such Expenses, judgments, penalties,
fines and amounts paid in settlement) actually and reasonably incurred by Indemnitee or on behalf of Indemnitee in connection with such Proceeding or any claim, issue or matter therein, but not, however, for the total amount thereof, the Company
shall nevertheless indemnify Indemnitee for the portion to which Indemnitee is entitled. 

  

	6.	Indemnification for Additional Expenses. 

  

	 	a.	The Company shall indemnify Indemnitee against any and all Expenses and, if requested by Indemnitee, shall (within seven (7) business days of such request) advance such
Expenses to Indemnitee, which are incurred by Indemnitee in connection with any action brought by Indemnitee for (i) indemnification or advance payment of Expenses by the Company under this Agreement or any other agreement or by-law of the
Company now or hereafter in effect; or (ii) recovery under any directors’ and officers’ liability insurance policies maintained by the Company, regardless of whether Indemnitee ultimately is determined to be entitled to such
indemnification, advance expense payment or insurance recovery, as the case may be. 

  

	 	b.	Notwithstanding any other provision of this Agreement, to the extent that Indemnitee is, by reason of Indemnitee’s Corporate Status, a witness in any Proceeding to which
Indemnitee is not a party, Indemnitee shall be indemnified against all Expenses actually and reasonably incurred by Indemnitee or on behalf of Indemnitee in connection therewith. 

  

	7.	 Advancement of Expenses. The Company shall advance all reasonable Expenses incurred by or on behalf of Indemnitee in connection with any Proceeding within
seven (7) days after the receipt 

  

 2 

	 	 
by the Company of a statement or statements from Indemnitee requesting such advance or advances from time to time, whether prior to or after final
disposition of such Proceeding. Such statement or statements shall reasonably evidence the Expenses incurred by Indemnitee and shall include or be preceded or accompanied by an undertaking by or on behalf of Indemnitee to repay any Expenses advanced
if it shall ultimately be determined that Indemnitee is not entitled to be indemnified against such Expenses. Notwithstanding the foregoing, the obligation of the Company to advance Expenses pursuant to this Section 7 shall be subject to the
condition that, if, when and to the extent that the Company determines that Indemnitee would not be permitted to be indemnified under applicable law, the Company shall be entitled to be reimbursed, within thirty (30) days of such determination,
by Indemnitee (who hereby agrees to reimburse the Company) for all such amounts theretofore paid; provided, however, that if Indemnitee has commenced or thereafter commences legal proceedings in a court of competent jurisdiction to
secure a determination that Indemnitee should be indemnified under applicable law, any determination made by the Company that Indemnitee would not be permitted to be indemnified under applicable law shall not be binding and Indemnitee shall not be
required to reimburse the Company for any advance of Expenses until a final judicial determination is made with respect thereto (as to which all rights of appeal therefrom have been exhausted or lapsed). 

  

	8.	Procedure for Determination of Entitlement to Indemnification. 

  

	 	a.	To obtain indemnification under this Agreement, Indemnitee shall submit to the Company a written request, including therein or therewith such documentation and information as is
reasonably available to Indemnitee and is reasonably necessary to determine whether and to what extent Indemnitee is entitled to indemnification. The Secretary of the Company shall, promptly upon receipt of such a request for indemnification, advise
the Board in writing that Indemnitee has requested indemnification. 

  

	 	b.	Upon written request by Indemnitee for indemnification pursuant to the first sentence of Section 8(a) hereof, a determination, if required by applicable law, with respect to
Indemnitee’s entitlement thereto shall be made in the specific case: (i) if a Change in Control (as hereinafter defined) shall have occurred, by Independent Counsel (as hereinafter defined) in a written opinion to the Board of Directors, a
copy of which shall be delivered to Indemnitee; or (ii) if a Change of Control shall not have occurred, (A) by a majority vote of the Disinterested Directors (as hereinafter defined), even though less than a quorum of the Board, or
(B) if there are no such Disinterested Directors or, if such Disinterested Directors so direct, by Independent Counsel in a written opinion to the Board, a copy of which shall be delivered to Indemnitee or (C) if so directed by the Board,
by the stockholders of the Company; and, if it is so determined that Indemnitee is entitled to indemnification, payment to Indemnitee shall be made within seven (7) days after such determination. The Company and Indemnitee shall each cooperate
with the person, persons or entity making such determination with respect to Indemnitee’s entitlement to indemnification, including providing to such person, persons or entity upon reasonable advance request any documentation or information
which is not privileged or otherwise protected from disclosure and which is reasonably available to Indemnitee and reasonably necessary to such determination. Any costs or expenses (including attorneys’ fees and disbursements) incurred by
Indemnitee in so cooperating with the person, persons or entity making such determination shall be borne by the Company (irrespective of the determination as to Indemnitee’s entitlement to indemnification), and the Company hereby indemnifies
and agrees to hold Indemnitee harmless therefrom. 

  

 3 

	 	c.	In the event the determination of entitlement to indemnification is to be made by Independent Counsel pursuant to Section 8(b) hereof, the Independent Counsel shall be selected
as provided in this Section 8(c). If a Change of Control shall not have occurred, the Independent Counsel shall be selected by the Board of Directors, and the Company shall give written notice to Indemnitee advising him of the identity of the
Independent Counsel so selected. If a Change of Control shall have occurred, the Independent Counsel shall be selected by Indemnitee (unless Indemnitee shall request that such selection be made by the Board of Directors, in which event the preceding
sentence shall apply), and Indemnitee shall give written notice to the Company advising it of the identity of the Independent Counsel so selected. In either event, Indemnitee or the Company, as the case may be, may, within 10 days after such written
notice of selection shall have been given, deliver to the Company or to Indemnitee, as the case may be, a written objection to such selection; provided, however, that such objection may be asserted only on the ground that the
Independent Counsel so selected does not meet the requirements of “Independent Counsel” as defined in Section 17 of this Agreement, and the objection shall set forth with particularity the factual basis of such assertion. If such
written objection is so made and substantiated, the Independent Counsel so selected may not serve as Independent Counsel unless and until such objection is withdrawn or a court has determined that such objection is without merit. If, within 20 days
after submission by Indemnitee of a written request for indemnification pursuant to Section 8(a) hereof, no Independent Counsel shall have been selected and not objected to, either the Company or Indemnitee may petition the Court of Chancery of
the State of Delaware for resolution of any objection which shall have been made by the Company or Indemnitee to the other’s selection of Independent Counsel and/or for the appointment as Independent Counsel of a person selected by the Court or
by such other person as the Court shall designate, and the person with respect to whom all objections are so resolved or the person so appointed shall act as Independent Counsel under Section 8(b) hereof. The Company shall pay any and all
reasonable fees and expenses of Independent Counsel incurred by such Independent Counsel in connection with acting pursuant to Section 8(b) hereof, and the Company shall pay all reasonable fees and expenses incident to the procedures of this
Section 8(c), regardless of the manner in which such Independent Counsel was selected or appointed, and if such Independent Counsel was selected or appointed by Indemnitee or the Court, shall provide such Independent Counsel with such retainer
as may requested by such counsel. Upon the due commencement of any judicial proceeding or arbitration pursuant to Section 10(a)(iii) of this Agreement, Independent Counsel shall be discharged and relieved of any further responsibility in such
capacity (subject to the applicable standards of professional conduct then prevailing). 

  

	 	d.	The Company shall not be required to obtain the consent of Indemnitee to the settlement of any Proceeding which the Company has undertaken to defend if the Company assumes full and
sole responsibility for such settlement and the settlement grants Indemnitee a complete and unqualified release in respect of the potential liability. The Company shall not be liable for any amount paid by Indemnitee in settlement of any Proceeding
that is not defended by the Company, unless the Company has consented to such settlement, which consent shall not be unreasonably withheld. 

  

 4 

	9.	Presumptions and Effect of Certain Proceedings. 

  

	 	a.	In making a determination with respect to entitlement to indemnification or the advancement of expenses hereunder, the person or persons or entity making such determination shall
presume that Indemnitee is entitled to indemnification or advancement of expenses under this Agreement if Indemnitee has submitted a request for indemnification or the advancement of expenses in accordance with Section 8(a) of this Agreement,
and the Company shall have the burden of proof to overcome that presumption in connection with the making by any person, persons or entity of any determination contrary to that presumption. Neither the failure of the Company (including its board of
directors or independent legal counsel) to have made a determination prior to the commencement of any action pursuant to this Agreement that indemnification is proper in the circumstances because Indemnitee has met the applicable standard of
conduct, nor an actual determination by the Company (including its board of directors or independent legal counsel) that Indemnitee has not met such applicable standard of conduct, shall be a defense to the action or create a presumption that
Indemnitee has not met the applicable standard of conduct. 

  

	 	b.	If the person, persons or entity empowered or selected under Section 8 of this Agreement to determine whether Indemnitee is entitled to indemnification shall not have made a
determination within sixty (60) days after receipt by the Company of the request therefor, the requisite determination of entitlement to indemnification shall be deemed to have been made and Indemnitee shall be entitled to such indemnification,
absent (i) a misstatement by Indemnitee of a material fact, or an omission of a material fact necessary to make Indemnitee’s statement not materially misleading, in connection with the request for indemnification, or (ii) a
prohibition of such indemnification under applicable law; provided, however, that such 60-day period may be extended for a reasonable time, not to exceed an additional thirty (30) days, if the person, persons or entity making the
determination with respect to entitlement to indemnification in good faith requires such additional time for the obtaining or evaluating of documentation and/or information relating thereto; and provided, further, that the foregoing provisions of
this Section 9(b) shall not apply (i) if the determination of entitlement to indemnification is to be made by the stockholders pursuant to Section 8(b) of this Agreement and if (A) within fifteen (15) days after receipt by
the Company of the request for such determination the Board of Directors has resolved to submit such determination to the stockholders for their consideration at an annual meeting thereof to be held within seventy-five (75) days after such
receipt and such determination is made thereat, or (B) a special meeting of stockholders is called within fifteen (15) days after such receipt for the purpose of making such determination, such meeting is held for such purpose within sixty
(60) days after having been so called and such determination is made thereat, or (ii) if the determination of entitlement to indemnification is to be made by Independent Counsel pursuant to Section 8(b) of this Agreement.

  

	 	c.	The termination of any Proceeding or of any claim, issue or matter therein, by judgment, order, settlement or conviction, or upon a plea of nolo contendere or its equivalent,
shall not (except as otherwise expressly provided in this Agreement) of itself adversely affect the right of Indemnitee to indemnification or create a presumption that Indemnitee did not act in good faith and in a manner which he reasonably believed
to be in or not opposed to the best interests of the Company or, with respect to any criminal Proceeding, that Indemnitee had reasonable cause to believe that his conduct was unlawful. 

  

 5 

	 	d.	Reliance as Safe Harbor. For purposes of any determination of good faith, Indemnitee shall be deemed to have acted in good faith if Indemnitee’s action is based on the
records or books of account of the Company or relevant enterprise, including financial statements, or on information supplied to Indemnitee by the officers of the Company or relevant enterprise in the course of their duties, or on the advice of
legal counsel for the Company or relevant enterprise or on information or records given in reports made to the Company or relevant enterprise by an independent certified public accountant or by an appraiser or other expert selected with reasonable
care by the Company or relevant enterprise. The provisions of this Section 9(d) shall not be deemed to be exclusive or to limit in any way the other circumstances in which Indemnitee may be deemed to have met the applicable standard of conduct
set forth in this Agreement. 

  

	 	e.	Actions of Others. The knowledge and/or actions, or failure to act, of any director, officer, agent or employee of the Company or relevant enterprise shall not be imputed to
Indemnitee for purposes of determining the right to indemnification under this Agreement. 

  

	10.	Remedies of Indemnitee. 

  

	 	a.	In the event that (i) a determination is made pursuant to Section 8 of this Agreement that Indemnitee is not entitled to indemnification under this Agreement,
(ii) advancement of Expenses is not timely made pursuant to Section 7 of this Agreement, (iii) no determination of entitlement to indemnification shall have been made pursuant to Section 8(b) of this Agreement within 90 days
after receipt by the Company of the request for indemnification, (iv) payment of indemnification is not made pursuant to Section 5 or 6 of this Agreement within ten (10) days after receipt by the Company of a written request therefor,
or (v) payment of indemnification is not made within ten (10) days after a determination has been made that Indemnitee is entitled to indemnification, Indemnitee shall be entitled to an adjudication by the Court of Chancery of the State of
Delaware, or any other court of competent jurisdiction, of his entitlement to such indemnification or advancement of Expenses. Alternatively, Indemnitee, at his option, may seek an award in arbitration to be conducted by a single arbitrator pursuant
to the Commercial Arbitration Rules of the American Arbitration Association. 

  

	 	b.	In the event that a determination shall have been made pursuant to Section 8(b) of this Agreement that Indemnitee is not entitled to indemnification, any judicial proceeding or
arbitration commenced pursuant to this Section 10 shall be conducted in all respects as a de novo trial, or arbitration, on the merits and Indemnitee shall not be prejudiced by reason of that adverse determination. If a Change of Control
shall have occurred, in any judicial proceeding or arbitration commenced pursuant to this Section 10, the Company shall have the burden of proving that Indemnitee is not entitled to indemnification or advancement of Expenses, as the case may
be. 

  

	 	c.	 If a determination shall have been made pursuant to Section 8(b) of this Agreement that Indemnitee is entitled to indemnification, the Company shall be bound
by such determination in any judicial proceeding or arbitration commenced pursuant to this 

  

 6 

	 	 
Section 10, absent (i) a misstatement by Indemnitee of a material fact, or an omission of a material fact necessary to make Indemnitee’s
statement not materially misleading in connection with the request for indemnification, or (ii) a prohibition of such indemnification under applicable law. 

  

	 	d.	In the event that Indemnitee, pursuant to this Section 10, seeks a judicial adjudication of or an award in arbitration to enforce his rights under, or to recover damages for
breach of, this Agreement, Indemnitee shall be entitled to recover from the Company, and shall be indemnified by the Company against, any and all expenses (of the types described in the definition of Expenses in Section 17 of this Agreement)
actually and reasonably incurred by him in such judicial adjudication or arbitration, but only if he prevails therein. If it shall be determined in said judicial adjudication or arbitration that Indemnitee is entitled to receive part but not all of
the indemnification or advancement of expenses sought, the expenses incurred by Indemnitee in connection with such judicial adjudication or arbitration shall be appropriately prorated. The Company shall indemnify Indemnitee against any and all
Expenses and, if requested by Indemnitee, shall (within ten (10) days after receipt by the Company of a written request therefor) advance such expenses to Indemnitee, which are incurred by Indemnitee in connection with any action brought by
Indemnitee for indemnification or advance of Expenses from the Company under this Agreement or under any directors’ or officers’ liability insurance policies maintained by the Company, regardless of whether Indemnitee ultimately is
determined to be entitled to such indemnification, advancement of Expenses or insurance recovery, as the case may be. 

  

	 	e.	The Company shall be precluded from asserting in any judicial proceeding or arbitration commenced pursuant to this Section 10 that the procedures and presumptions of this
Agreement are not valid, binding and enforceable and shall stipulate in any such court or before any such arbitrator that the Company is bound by all the provisions of this Agreement. 

  

	11.	Non-Exclusivity; Survival of Rights; Insurance; Subrogation. 

  

	 	a.	The rights of indemnification and to receive advancement of Expenses as provided by this Agreement shall not be deemed exclusive of any other rights to which Indemnitee may at any
time be entitled under applicable law, the Certificate of Incorporation, the By-Laws, any agreement, a vote of stockholders or a resolution of directors, or otherwise. No amendment, alteration or repeal of this Agreement or of any provision hereof
shall limit or restrict any right of Indemnitee under this Agreement in respect of any action taken or omitted by such Indemnitee in Indemnitee’s Corporate Status prior to such amendment, alteration or repeal. To the extent that a change in the
General Corporation Law of the State of Delaware, whether by statute or judicial decision, permits greater indemnification or advancement of Expenses than would be afforded currently under the Company’s By-Laws and this Agreement, it is the
intent of the parties hereto that Indemnitee shall enjoy by this Agreement the greater benefits so afforded by such change. No right or remedy herein conferred is intended to be exclusive of any other right or remedy, and every other right and
remedy shall be cumulative and in addition to every other right and remedy given hereunder or now or hereafter existing at law or in equity or otherwise. The assertion or employment of any right or remedy hereunder, or otherwise, shall not prevent
the concurrent assertion or employment of any other right or remedy. 

  

 7 

	 	b.	To the extent that the Company maintains an insurance policy or policies providing liability insurance for directors, officers, employees or agents of the Company or of any other
corporation, partnership, joint venture, trust, employee benefit plan or other enterprise which such person serves at the request of the Company, Indemnitee shall be covered by such policy or policies in accordance with its or their terms to the
maximum extent of the coverage available for any such director, officer, employee or agent under such policy or policies. 

  

	 	c.	In the event of any payment under this Agreement, the Company shall be subrogated to the extent of such payment to all of the rights of recovery of Indemnitee, who shall execute all
papers required and take all action necessary to secure such rights, including execution of such documents as are necessary to enable the Company to bring suit or enforce such rights. 

  

	 	d.	The Company shall not be liable under this Agreement to make any payment of amounts otherwise indemnifiable hereunder if and to the extent that Indemnitee has otherwise actually
received such payment under any insurance policy, contract, agreement or otherwise. 

  

	 	e.	The Company’s obligation to indemnify or advance expenses hereunder to Indemnitee who is or was serving at the request of the Company as a director, officer, employee or agent
of any other corporation, partnership, joint venture, trust, employee benefit plan or other enterprise shall be reduced by any amount Indemnitee has actually received as indemnification or advancement of expenses from such other corporation,
partnership, joint venture, trust, employee benefit plan or other enterprise. 

  

	12.	Duration of Agreement. 

  

	 	a.	This Agreement shall continue until and terminate upon the later of: (i) 10 years after the date that Indemnitee shall have ceased to serve as a director of the Company (or of
any other corporation, partnership, joint venture, trust, employee benefit plan or other enterprise which Indemnitee served at the request of the Company); or (ii) the final termination of any Proceeding then pending in respect of which
Indemnitee is granted rights of indemnification or advancement of expenses hereunder and of any proceeding commenced by Indemnitee pursuant to Section 10 of this Agreement relating thereto. 

  

	 	b.	This Agreement shall not be deemed an employment contract between the Company (or any of its subsidiaries) and Indemnitee. Indemnitee specifically acknowledges that Indemnitee may
be discharged from service as a director at any time for any reason, with or without cause, except as may be otherwise provided, by the Company’s Certificate of Incorporation, By-laws, and the General Corporation Law of the State of Delaware.
The foregoing notwithstanding, this Agreement shall continue in force as provided above after Indemnitee has ceased to serve as a director of the Company. 

  

	 	c.	This Agreement shall be binding upon the Company and its successors and assigns and shall inure to the benefit of Indemnitee and his heirs, executors and administrators.

  

 8 

	13.	Severability. If any provision or provisions of this Agreement shall be held to be invalid, illegal or unenforceable for any reason whatsoever: (a) the validity,
legality and enforceability of the remaining provisions of this Agreement (including without limitation, each portion of any Section of this Agreement containing any such provision held to be invalid, illegal or unenforceable, that is not itself
invalid, illegal or unenforceable) shall not in any way be affected or impaired thereby; (b) such provision or provisions shall be deemed reformed to the extent necessary to conform to applicable law and to give the maximum effect to the intent
of the parties hereto; and (c) to the fullest extent possible, the provisions of this Agreement (including, without limitation, each portion of any Section of this Agreement containing any such provision held to be invalid, illegal or
unenforceable, that is not itself invalid, illegal or unenforceable) shall be construed so as to give effect to the intent manifested thereby. 

  

	14.	Exception to Right of Indemnification or Advancement of Expenses. Except as provided in Section 6(a) of this Agreement, Indemnitee shall not be entitled to
indemnification or advancement of Expenses under this Agreement with respect to any Proceeding brought by Indemnitee (other than a Proceeding by Indemnitee to enforce his rights under this Agreement or his right as a director to inspect corporate
records under Section 220 of the Delaware General Corporation Law), or any claim therein, unless the bringing of such Proceeding or making of such claim shall have been approved by the Board of Directors. For purposes of this paragraph, a
defense or counterclaim brought by Indemnitee in defense of a Proceeding brought against Indemnitee shall not constitute a proceeding brought by Indemnitee. 

  

	15.	Identical Counterparts. This Agreement may be executed in one or more counterparts, each of which shall for all purposes be deemed to be an original but all of which together
shall constitute one and the same Agreement. Only one such counterpart signed by the party against whom enforceability is sought needs to be produced to evidence the existence of this Agreement. 

  

	16.	Headings. The headings of the paragraphs of this Agreement are inserted for convenience only and shall not be deemed to constitute part of this Agreement or to affect the
construction thereof. 

  

	17.	Definitions. For purposes of this Agreement: 

  

	 	a.	“Change in Control” means: 

  

	 	i.	The acquisition by any person, corporation, partnership, limited liability company or other entity (a “Person”, which term shall include a group within the meaning of
section 13(d) of the Securities Exchange Act of 1934 (the “Exchange Act”)) of ultimate beneficial ownership (within the meaning of Rule 13d-3 promulgated under the Exchange Act), directly or indirectly of 30% or more of either (i) the
then outstanding shares of common stock of the Company (the “Outstanding Company Common Stock”) or (ii) the combined voting power of the then outstanding voting securities of the Company entitled to vote generally in the election of
directors (the “Outstanding Company Voting Securities”); provided, however, that for purposes of this subsection (a), the following acquisitions shall not constitute a Change of Control: (i) any such acquisition directly from the
Company, except for acquisition of securities upon conversion of other securities of the Company (ii) any such acquisition by the Company, (iii) any such acquisition by any employee benefit plan (or related trust) sponsored or maintained
by the Company or any corporation controlled by the Company or (iv) any such acquisition by any corporation pursuant to a transaction which complies with clauses (1), (2) and (3) of subsection (iii) of this Section 17(a); or

  

 9 

	 	ii.	Individuals who, as of the date hereof, constitute the Board (the “Incumbent Board”) cease for any reason to constitute at least a majority of the Board; provided,
however, that any individual becoming a director subsequent to the date hereof whose election, or nomination for election, by the Company’s stockholders, was approved by a vote of at least a majority of the directors then comprising the
Incumbent Board shall be considered as though such individual were a member of the Incumbent Board, but excluding, for this purpose, any such individual whose initial assumption of office occurs as a result of an actual or threatened election
contest with respect to the election or removal of directors or other actual or threatened solicitation of proxies or consents by or on behalf of a Person other than the Board; or 

  

	 	iii.	Consummation of a reorganization, merger or consolidation or sale or other disposition of all or substantially all of the assets of the Company in one or a series of transactions (a
“Business Combination”), in each case, unless, following such Business Combination, (1) all or substantially all of the individuals and entities who were the beneficial owners, respectively, of the Outstanding Company Common Stock and
Outstanding Company Voting Securities immediately prior to such Business Combination beneficially own, directly or indirectly, immediately following such Business Combination more than 50% of, respectively, the outstanding shares of common stock and
the combined voting power of the then outstanding voting securities entitled to vote generally in the election of directors, as the case may be, of the corporation resulting from such Business Combination (including, without limitation, a
corporation which as a result of such transaction owns the Company or all or substantially all of the Company’s assets either directly or through one or more subsidiaries) in substantially the same proportions as their ownership, immediately
prior to such Business Combination of the Outstanding Company Common Stock and outstanding Company Voting Securities, as the case may be, (2) no Person (excluding any corporation resulting from such Business Combination or any employee benefit
plan (or related trust) of the Company or such corporation resulting from such Business Combination) ultimately beneficially owns, directly or indirectly, 30% or more of, respectively, the then outstanding shares of common stock of the corporation
resulting from such Business Combination or the combined voting power of the then outstanding voting securities of such corporation except to the extent that such ownership existed prior to the Business Combination and (3) at least a majority
of the members of the board of directors of the corporation resulting from such Business Combination were members of the Incumbent Board at the time of the execution of the initial agreement, or of the action of the Board, providing for such
Business Combination; or 

  

	 	iv.	approval by the stockholders of the Company of a complete liquidation or dissolution of the Company. 

  

	 	b.	“Corporate Status” describes the status of a person who is or was a director, officer, employee, fiduciary or agent of the Company or of any other corporation,
partnership, joint venture, trust, employee benefit plan or other enterprise which such person is or was serving at the request of the Company. 

  

 10 

	 	c.	“Disinterested Director” means a director of the company who is not and was not a party to the Proceeding in respect of which indemnification is sought by Indemnitee.

  

	 	d.	“Effective Date” means the date the Company’s Registration Statement on Form S-1 (No. 333-121173) is declared effective by the Securities and Exchange Commission.

  

	 	e.	“Expenses” shall include all reasonable attorneys’ fees, retainers, court costs, transcript costs, fees of experts, witness fees, travel expenses, duplicating costs,
printing and binding costs, telephone charges, postage, delivery service fees, and all other disbursements or expenses of the types customarily incurred in connection with prosecuting, defending, preparing to prosecute or defend, investigating,
being or preparing to be a witness, in, or otherwise participating in, a Proceeding. 

  

	 	f.	“Independent Counsel” means a law firm, or a member of a law firm, that is experienced in matters of corporation law and neither presently is, nor in the past five years
has been, retained to represent: (i) the Company or Indemnitee in any matter material to either such party, or (ii) any other party to the Proceeding giving rise to a claim for indemnification hereunder. Notwithstanding the foregoing, the
term “Independent Counsel” shall not include any person who, under the applicable standards of professional conduct then prevailing, would have a conflict of interest in representing either the Company or Indemnitee in an action to
determine Indemnitee’s rights under this Agreement. The Company agrees to pay the reasonable fees of the Independent Counsel referred to above and to fully indemnify such counsel against any and all Expenses, claims, liabilities and damages
arising out of or relating to this Agreement or its engagement pursuant hereto. 

  

	 	g.	“Proceeding” includes any threatened, pending or completed action, suit, arbitration, alternate dispute resolution mechanism, investigation, inquiry, administrative
hearing or any other actual, threatened or completed proceeding, whether brought by or in the right of the Company or otherwise and whether civil, criminal, administrative or investigative, in which Indemnitee was, is, may be or will be involved as
a party or otherwise, by reason of the fact that Indemnitee is or was a director of the Company, by reason of any action taken by him or of any inaction on his part while acting as director of the Company, or by reason of the fact that he is or was
serving at the request of the Company as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other enterprise; in each case whether or not he is acting or serving in any such capacity at the time any
liability or expense is incurred for which indemnification or advancement of expenses can be provided under this Agreement; except one (i) initiated by an Indemnitee pursuant to Section 10 of this Agreement to enforce his right under this
Agreement or (ii) pending on or before the Effective Date. 

  

	18.	Enforcement. 

  

	 	a.	The Company expressly confirms and agrees that it has entered into this Agreement and assumed the obligations imposed on it hereby in order to induce Indemnitee to serve as a
director of the Company, and the Company acknowledges that Indemnitee is relying upon this Agreement in serving as a director of the Company. 

  

 11 

	 	b.	This Agreement constitutes the entire agreement between the parties hereto with respect to the subject matter hereof and supersedes all prior agreements and understandings, oral,
written and implied, between the parties hereto with respect to the subject matter hereof. 

  

	19.	Modification and Waiver. No supplement, modification or amendment of this Agreement shall be binding unless executed in writing by both of the parties hereto. No waiver of
any of the provisions of this Agreement shall be deemed or shall constitute a waiver of any other provisions hereof (whether or not similar) nor shall such waiver constitute a continuing waiver. 

  

	20.	Notice by Indemnitee. Indemnitee agrees promptly to notify the Company in writing upon being served with any summons, citation, subpoena, complaint, indictment, information
or other document relating to any Proceeding or matter which may be subject to indemnification or advancement of Expenses covered hereunder. The failure of Indemnitee to so notify the Company shall not relieve the Company of any obligation which it
may have to Indemnitee under this Agreement or otherwise. 

  

	21.	Notices. All notices, requests, demands or other communications hereunder shall be in writing and shall be deemed to have been duly given if (i) delivered by hand and
receipted for by the party to whom said notice or other communication shall have been direct, or (ii) mailed by certified or registered mail with postage prepaid, on the third business day after the date on which it is so mailed:

  

	 	a.	If to Indemnitee to: 

 [Indemnitee] 
 [ADDRESS] 
  

	 	b.	If to the Company to: 

 CombinatoRx, Incorporated

 245 First Street 
 Third
Floor 
 Cambridge, MA 02142 
 Attn: General Counsel 
 or to such other address as may have been furnished to Indemnitee by the Company or to the Company by
Indemnitee, as the case may be. 
  

	22.	Contribution. To the fullest extent permissible under applicable law, if the indemnification provided for in this Agreement is unavailable to Indemnitee for any reason
whatsoever, the Company, in lieu of indemnifying Indemnitee, shall contribute to the amount incurred by Indemnitee, whether for judgments, fines, penalties, excise taxes, amounts paid or to be paid in settlement and/or for Expenses, in connection
with any claim relating to an indemnifiable event under this Agreement, in such proportion as is deemed fair and reasonable in light of all of the circumstances of such Proceeding in order to reflect (i) the relative benefits received by the
Company and Indemnitee as a result of the event(s) and/or transaction(s) giving cause to such Proceeding; and/or (ii) the relative fault of the Company (and its directors, officers, employees and agents) and Indemnitee in connection with such
event(s) and/or transaction(s). 

  

 12 

	23.	Governing Law; Submission to Jurisdiction; Appointment of Agent for Service of Process. This Agreement and the legal relations among the parties shall be governed by, and
construed and enforced in accordance with, the laws of the State of Delaware, without regard to its conflict of laws rules. Except with respect to any arbitration commenced by Indemnitee pursuant to Section 10(a) of this Agreement, the Company
and Indemnitee hereby irrevocably and unconditionally (i) agree that any action or proceeding arising out of or in connection with this Agreement shall be brought only in the Chancery Court of the State of Delaware (the “Delaware
Court”), and not in any other state or federal court in the United States of America or any court in any other country, (ii) consent to submit to the exclusive jurisdiction of the Delaware Court for purposes of any action or proceeding
arising out of or in connection with this Agreement, (iii) appoint, to the extent such party is not a resident of the State of Delaware, irrevocably the Corporation Trust Center, 1209 Orange Street, City of Wilmington, County of New Castle,
Delaware, as its agent in the State of Delaware for acceptance of legal process in connection with any such action or proceeding against such party with the same legal force and validity as if served upon such party personally within the State of
Delaware, (iv) waive any objection to the laying of venue of any such action or proceeding in the Delaware Court, and (v) waive, and agree not to plead or to make, any claim that any such action or proceeding brought in the Delaware Court
has been brought in an improper or otherwise inconvenient forum. 

  

	24.	Miscellaneous. Use of the masculine pronoun shall be deemed to include usage of the feminine pronoun where appropriate. 

 [Remainder of Page Intentionally Blank] 
  

 13 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement on the day and year first above
written. 
  

			
	COMBINATORX, INCORPORATED
		
	By:	 	  

	Name:	 	
	Title:	 	
	
	INDEMNITEE:
	
	  

	Name:	 	
	Title:	 	

  

 14

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