Document:

EXHIBIT 10.44

                           PLEDGE AND ESCROW AGREEMENT

         THIS PLEDGE AND ESCROW AGREEMENT (the "Agreement") is made and entered
into as of September 9, 2005 (the "Effective Date") by and among CORD BLOOD
AMERICA, INC., a corporation organized and existing under the laws of the State
of Florida (the "Pledgor"), CORNELL CAPITAL PARTNERS, LP, (the "Pledgee"), and
DAVID GONZALEZ, ESQ., as escrow agent ("Escrow Agent").

                                    RECITALS:

         WHEREAS, in order to secure the full and prompt payment when due
(whether at the stated maturity, by acceleration or otherwise) of all of the
Company's obligations (the "Obligations") to the Pledgee or any successor to the
Pledgee under this Agreement, the Securities Purchase Agreement of even date
herewith between the Pledgor and the Pledgee (the "Securities Purchase
Agreement"), the Convertible Debentures (the "Convertible Debentures") issued or
to be issued by the Company to the Pledgee, either now or in the future, up to a
total of Five Million ($5,000,000) of principal, plus any interest, costs, fees,
and other amounts owed to the Pledgee thereunder, the Security Agreement of even
date herewith between the Pledgor and the Pledgee (the "Security Agreement"),
and all other contracts entered into between the parties hereto (collectively,
the "Transaction Documents"), the Pledgor has agreed to irrevocably pledge to
the Pledgee Thirty Four Million (34,000,000) shares (the "Pledged Shares") of
the Pledgor's common stock.

         NOW, THEREFORE, in consideration of the mutual covenants, agreements,
warranties, and representations herein contained, and for other good and
valuable consideration, the receipt and sufficiency of which is hereby
acknowledged, the parties hereto agree as follows:

                              TERMS AND CONDITIONS

         1.       PLEDGE AND TRANSFER OF PLEDGED SHARES.

         1.1.     The Pledgor hereby grants to Pledgee a security interest in
all Pledged Shares as security for Pledgor's obligations under the Convertible
Debentures. Simultaneously with the execution of the Transaction Documents, the
Pledgor shall deliver to the Escrow Agent stock certificates representing the
Pledged Shares, together with duly executed stock powers or other appropriate
transfer documents executed in blank by the Pledgor (the "Transfer Documents"),
and such stock certificates and Transfer Documents shall be held by the Escrow
Agent until the full payment of all amounts due to the Pledgee under the
Convertible Debentures and through repayment in accordance with the terms of the
Convertible Debentures, or the termination or expiration of this Agreement.

         2.       RIGHTS RELATING TO PLEDGED SHARES. Upon the occurrence of an
Event of Default (as defined herein), the Pledgee shall be entitled to vote the
Pledged Shares, to receive dividends and other distributions thereon, and to
enjoy all other rights and privileges incident to the ownership of the Pledged
Shares.

<PAGE>

         3.       RELEASE OF PLEDGED SHARES FROM PLEDGE. Upon the payment of all
amounts due to the Pledgee under the Convertible Debentures by repayment in
accordance with the terms of the Note, the parties hereto shall notify the
Escrow Agent to such effect in writing. Upon receipt of such written notice for
payment of the amounts due to the Pledgee under the Convertible Debentures, the
Escrow Agent shall return to the Pledgor the Transfer Documents and the
certificates representing the Pledged Shares, (collectively the "Pledged
Materials"), whereupon any and all rights of Pledgee in the Pledged Materials
shall be terminated. Notwithstanding anything to the contrary contained herein,
upon full payment of all amounts due to the Pledgee under the Convertible
Debentures, by repayment in accordance with the terms of the Note, this
Agreement and Pledgee's security interest and rights in and to the Pledged
Shares shall terminate.

         4.       EVENT OF DEFAULT. An "Event of Default" shall be deemed to
have occurred under this Agreement upon an Event of Default under the
Convertible Debentures.

         5.       REMEDIES. Upon and anytime after the occurrence of an Event of
Default, the Pledgee shall have the right to provide written notice of such
Event of Default (the "Default Notice") to the Escrow Agent, with a copy to the
Pledgor. As soon as practicable after receipt of the Default Notice, the Escrow
Agent shall deliver to Pledgee the Pledged Materials held by the Escrow Agent
hereunder. Upon receipt of the Pledged Materials, the Pledgee shall have the
right to (i) sell the Pledged Shares and to apply the proceeds of such sales,
net of any selling commissions, to the Obligations owed to the Pledgee by the
Pledgor under the Transaction Documents, including, without limitation,
outstanding principal, interest, legal fees, and any other amounts owed to the
Pledgee, and exercise all other rights and (ii) any and all remedies of a
secured party with respect to such property as may be available under the
Uniform Commercial Code as in effect in the State of New Jersey. To the extent
that the net proceeds received by the Pledgee are insufficient to satisfy the
Obligations in full, the Pledgee shall be entitled to a deficiency judgment
against the Pledgor for such amount. The Pledgee shall have the absolute right
to sell or dispose of the Pledged Shares in any manner it sees fit and shall
have no liability to the Pledgor or any other party for selling or disposing of
such Pledged Shares even if other methods of sales or dispositions would or
allegedly would result in greater proceeds than the method actually used. The
Escrow Agent shall have the absolute right to disburse the Pledged Shares to the
Pledgee in batches not to exceed 9.9% of the outstanding capital of the Pledgor
(which limit may be waived by the Pledgee providing not less than 65 days' prior
written notice to the Escrow Agent). The Pledgee shall return any Pledged Shares
released to it and remaining after the Pledgee has applied the net proceeds to
all amounts owed to the Pledgee.

                  5.1.     Each right, power and remedy of the Pledgee provided
for in this Agreement or any other Transaction Document shall be cumulative and
concurrent and shall be in addition to every other such right, power or remedy.
The exercise or beginning of the exercise by the Pledgee of any one or more of
the rights, powers or remedies provided for in this Agreement or any other
Transaction Document or now or hereafter existing at law or in equity or by
statute or otherwise shall not preclude the simultaneous or later exercise by
the Pledgee of all such other rights, powers or remedies, and no failure or
delay on the part of the Pledgee to exercise any such right, power or remedy
shall operate as a waiver thereof. No notice to or demand on the Pledgor in any
case shall entitle it to any other or further notice or demand in similar or
other circumstances or constitute a waiver of any of the rights of the Pledgee
to any other further action in any circumstances without demand or notice. The

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<PAGE>

Pledgee shall have the full power to enforce or to assign or contract is rights
under this Agreement to a third party.

                  5.2.     DEMAND REGISTRATION RIGHTS. In addition to all other
remedies available to the Pledgee, upon an Event of Default, the Pledgor shall
promptly, but in no event more than thirty (30) days after the date of the
Default Notice, file a registration statement to register with the Securities
and Exchange Commission the Pledged Shares for the resale by the Pledgee. The
Pledgor shall cause the registration statement to remain in effect until all of
the Pledged Shares have been sold by the Pledgee.

         6.       CONCERNING THE ESCROW AGENT.

                  6.1.     The Escrow Agent undertakes to perform only such
duties as are expressly set forth herein and no implied duties or obligations
shall be read into this Agreement against the Escrow Agent.

                  6.2.     The Escrow Agent may act in reliance upon any writing
or instrument or signature which it, in good faith, believes to be genuine, may
assume the validity and accuracy of any statement or assertion contained in such
a writing or instrument, and may assume that any person purporting to give any
writing, notice, advice or instructions in connection with the provisions hereof
has been duly authorized to do so. The Escrow Agent shall not be liable in any
manner for the sufficiency or correctness as to form, manner, and execution, or
validity of any instrument deposited in this escrow, nor as to the identity,
authority, or right of any person executing the same; and its duties hereunder
shall be limited to the safekeeping of such certificates, monies, instruments,
or other document received by it as such escrow holder, and for the disposition
of the same in accordance with the written instruments accepted by it in the
escrow.

                  6.3.     Pledgee and the Pledgor hereby agree, to defend and
indemnify the Escrow Agent and hold it harmless from any and all claims,
liabilities, losses, actions, suits, or proceedings at law or in equity, or any
other expenses, fees, or charges of any character or nature which it may incur
or with which it may be threatened by reason of its acting as Escrow Agent under
this Agreement; and in connection therewith, to indemnify the Escrow Agent
against any and all expenses, including attorneys' fees and costs of defending
any action, suit, or proceeding or resisting any claim (and any costs incurred
by the Escrow Agent pursuant to Sections 6.4 or 6.5 hereof). The Escrow Agent
shall be vested with a lien on all property deposited hereunder, for
indemnification of attorneys' fees and court costs regarding any suit,
proceeding or otherwise, or any other expenses, fees, or charges of any
character or nature, which may be incurred by the Escrow Agent by reason of
disputes arising between the makers of this escrow as to the correct
interpretation of this Agreement and instructions given to the Escrow Agent
hereunder, or otherwise, with the right of the Escrow Agent, regardless of the
instructions aforesaid, to hold said property until and unless said additional
expenses, fees, and charges shall be fully paid. Any fees and costs charged by
the Escrow Agent for serving hereunder shall be paid by the Pledgor.

                  6.4.     If any of the parties shall be in disagreement about
the interpretation of this Agreement, or about the rights and obligations, or

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<PAGE>

the propriety of any action contemplated by the Escrow Agent hereunder, the
Escrow Agent may, at its sole discretion deposit the Pledged Materials with the
Clerk of the United States District Court of New Jersey, sitting in Newark, New
Jersey, and, upon notifying all parties concerned of such action, all liability
on the part of the Escrow Agent shall fully cease and terminate. The Escrow
Agent shall be indemnified by the Pledgor, the Company and Pledgee for all
costs, including reasonable attorneys' fees in connection with the aforesaid
proceeding, and shall be fully protected in suspending all or a part of its
activities under this Agreement until a final decision or other settlement in
the proceeding is received.

                  6.5.     The Escrow Agent may consult with counsel of its own
choice (and the costs of such counsel shall be paid by the Pledgor and Pledgee)
and shall have full and complete authorization and protection for any action
taken or suffered by it hereunder in good faith and in accordance with the
opinion of such counsel. The Escrow Agent shall not be liable for any mistakes
of fact or error of judgment, or for any actions or omissions of any kind,
unless caused by its willful misconduct or gross negligence.

                  6.6.     The Escrow Agent may resign upon ten (10) days'
written notice to the parties in this Agreement. If a successor Escrow Agent is
not appointed within this ten (10) day period, the Escrow Agent may petition a
court of competent jurisdiction to name a successor.

                  6.7      Conflict Waiver. The Pledgor hereby acknowledges that
the Escrow Agent is general counsel to the Pledgee, a partner in the general
partner of the Pledgee, and counsel to the Pledgee in connection with the
transactions contemplated and referred herein. The Pledgor agrees that in the
event of any dispute arising in connection with this Agreement or otherwise in
connection with any transaction or agreement contemplated and referred herein,
the Escrow Agent shall be permitted to continue to represent the Pledgee and the
Pledgor will not seek to disqualify such counsel and waives any objection
Pledgor might have with respect to the Escrow Agent acting as the Escrow Agent
pursuant to this Agreement.

                  6.8      Notices. Unless otherwise provided herein, all
demands, notices, consents, service of process, requests and other
communications hereunder shall be in writing and shall be delivered in person or
by overnight courier service, or mailed by certified mail, return receipt
requested, addressed:

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<PAGE>

If to the Pledgor, to:       Cord Blood America, Inc.
                             9000 W. Sunset Boulevard, Suite 4000
                             Los Angeles, CA 90069
                             Attention:        Matthew Schissler
                             Telephone:        (310) 432-4090
                             Facsimile:        (310) 432-4098

With a copy to:              Kirkpatrick & Lockhart Nicholson Graham, LLP
                             201 South Biscayne Boulevard, Suite 2000
                             Miami, Florida 33131
                             Attention:        Clayton E. Parker, Esq.
                             Telephone:        (305) 539-3306
                             Facsimile:        (305) 328-7095

If to the Pledgee:           Cornell Capital Partners, LP
                             101 Hudson Street, Suite 3700
                             Jersey City, NJ 07302
                             Attention:        Mark A. Angelo
                             Telephone:        (201) 985-8300
                             Facsimile:        (201) 985-8744

With copy to:                David Gonzalez, Esq.
                             101 Hudson Street, Suite 3700
                             Jersey City, NJ 07302
                             Telephone:        (201) 985-8300
                             Facsimile:        (201) 985-1964

Any such notice shall be effective (a) when delivered, if delivered by hand
delivery or overnight courier service, or (b) five (5) days after deposit in the
United States mail, as applicable.

         7.       BINDING EFFECT. All of the covenants and obligations contained
herein shall be binding upon and shall inure to the benefit of the respective
parties, their successors and assigns.

         8.       GOVERNING LAW; VENUE; SERVICE OF PROCESS. The validity,
interpretation and performance of this Agreement shall be determined in
accordance with the laws of the State of New Jersey applicable to contracts made
and to be performed wholly within that state except to the extent that Federal
law applies. The parties hereto agree that any disputes, claims, disagreements,
lawsuits, actions or controversies of any type or nature whatsoever that,
directly or indirectly, arise from or relate to this Agreement, including,
without limitation, claims relating to the inducement, construction, performance
or termination of this Agreement, shall be brought in the state superior courts
located in Hudson County, New Jersey or Federal district courts located in
Newark, New Jersey, and the parties hereto agree not to challenge the selection
of that venue in any such proceeding for any reason, including, without
limitation, on the grounds that such venue is an inconvenient forum. The parties
hereto specifically agree that service of process may be made, and such service
of process shall be effective if made, pursuant to Section 8 hereto.

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<PAGE>

         9.       ENFORCEMENT COSTS. If any legal action or other proceeding is
brought for the enforcement of this Agreement, or because of an alleged dispute,
breach, default or misrepresentation in connection with any provisions of this
Agreement, the successful or prevailing party or parties shall be entitled to
recover reasonable attorneys' fees, court costs and all expenses even if not
taxable as court costs (including, without limitation, all such fees, costs and
expenses incident to appeals), incurred in that action or proceeding, in
addition to any other relief to which such party or parties may be entitled.

         10.      REMEDIES CUMULATIVE. No remedy herein conferred upon any party
is intended to be exclusive of any other remedy, and each and every such remedy
shall be cumulative and shall be in addition to every other remedy given
hereunder or now or hereafter existing at law, in equity, by statute, or
otherwise. No single or partial exercise by any party of any right, power or
remedy hereunder shall preclude any other or further exercise thereof.

         11.      COUNTERPARTS. This Agreement may be executed in one or more
counterparts, each of which shall be deemed an original, but all of which
together shall constitute the same instrument.

         12.      NO PENALTIES. No provision of this Agreement is to be
interpreted as a penalty upon any party to this Agreement.

         13.      JURY TRIAL. EACH OF THE PLEDGEE AND THE PLEDGOR HEREBY
KNOWINGLY, VOLUNTARILY AND INTENTIONALLY WAIVES THE RIGHT WHICH IT MAY HAVE TO A
TRIAL BY JURY OF ANY CLAIM, DEMAND, ACTION OR CAUSE OF ACTION BASED HEREON, OR
ARISING OUT OF, UNDER OR IN ANY WAY CONNECTED WITH THE DEALINGS BETWEEN PLEDGEE
AND PLEDGOR, THIS PLEDGE AND ESCROW AGREEMENT OR ANY DOCUMENT EXECUTED IN
CONNECTION HEREWITH, OR ANY COURSE OF CONDUCT, COURSE OF DEALING, STATEMENTS
(WHETHER ORAL OR WRITTEN) OR ACTIONS OF ANY PARTY HERETO OR THERETO IN EACH CASE
WHETHER NOW EXISTING OR HEREAFTER ARISING, AND WHETHER IN CONTRACT, TORT, EQUITY
OR OTHERWISE.

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<PAGE>

         IN WITNESS WHEREOF, the parties hereto have duly executed this Pledge
and Escrow Agreement as of the date first above written.

                            CORNELL CAPITAL PARTNERS, LP

                            By:  Yorkville Advisors, LLC
                            Its: General Partner

                            By:_______________________________________
                            Name:  Mark Angelo
                            Title: Portfolio Manager

                            CORD BLOOD AMERICA, INC.

                            By:_______________________________________
                            Name:  Matthew Schissler
                            Title: Chairman and Chief Executive Officer

                            ESCROW AGENT

                            By:_______________________________________
                            Name: David Gonzalez, Esq.

                                       7EXHIBIT 10.45

                       INSIDER PLEDGE AND ESCROW AGREEMENT
                       -----------------------------------

         THIS INSIDER PLEDGE AND ESCROW AGREEMENT (the "Agreement") is made and
entered into as of September 9, 2005 (the "Effective Date") by and among CORNELL
CAPITAL PARTNERS, LP (the "Pledgee"), CORD BLOOD AMERICA, INC., a Florida
corporation (the "Company"), MATTHEW L. SCHISSLER (the "Pledgor") and DAVID
GONZALEZ, ESQ., as escrow agent ("Escrow Agent").

                                    RECITALS:
                                    ---------

         WHEREAS, in order to secure the full and prompt payment when due
(whether at the stated maturity, by acceleration or otherwise) of all of the
Company's obligations (the "Obligations") to the Pledgee or any successor to the
Pledgee under this Agreement, the Securities Purchase Agreement of even date
herewith between the Pledgor and the Pledgee (the "Securities Purchase
Agreement"), the Convertible Debentures (the "Convertible Debentures") issued or
to be issued by the Company to the Pledgee, either now or in the future, up to a
total of Five Million ($5,000,000) of principal, plus any interest, costs, fees,
and other amounts owed to the Pledgee thereunder, the Security Agreement of even
date herewith between the Pledgor and the Pledgee (the "Security Agreement"),
and all other related contracts entered into between the parties hereto
(collectively, the "Transaction Documents"), the Pledgor has agreed to
irrevocably pledge to the Pledgee a total of Seven Million Seven Hundred Seventy
Thousand (7,770,000) shares (the "Pledged Shares") of common stock of the
Company beneficially owned by the Pledgor.

         NOW, THEREFORE, in consideration of the mutual covenants, agreements,
warranties, and representations herein contained, and for other good and
valuable consideration, the receipt and sufficiency of which is hereby
acknowledged, the parties hereto agree as follows:

                              TERMS AND CONDITIONS
                              --------------------

         1. PLEDGE AND TRANSFER OF PLEDGED SHARES. The Pledgor hereby grants to
Pledgee an irrevocable, first priority security interest in all Pledged Shares
as security for the Company's obligations under the Transaction Documents. On or
before the closing of the Transaction Documents, the Pledgor shall deliver to
the Escrow Agent stock certificates representing the Pledged Shares, together
with duly executed stock powers or other appropriate transfer documents with
medallion bank guarantees and executed in blank by the Pledgor (the "Transfer
Documents"), and such stock certificates and Transfer Documents shall be held by
the Escrow Agent until the full payment of all Obligations due to the Pledgee
under the Transaction Documents, including the repayment of all amounts owed by
the Company to the Pledgee under the Promissory Notes (whether outstanding
principal, interest, legal fees, or any other amounts owed to the Pledgee by the
Company).

<PAGE>

         2. RIGHTS RELATING TO PLEDGED SHARES. Upon the occurrence of an Event
of Default (as defined herein), the Pledgee shall be entitled to vote the
Pledged Shares, receive dividends and other distributions thereon, and enjoy all
other rights and privileges incident to the ownership of the number of Pledged
Shares actually released from escrow in accordance with Section 5.1 hereof.

         3. RELEASE OF PLEDGED SHARES FROM PLEDGE. When the Company has made
each of its monthly interest payments due under the Convertible Debentures for a
period of 12 calendar months, including the repayment of all amounts owed by the
Company to the Pledgee under the Promissory Notes (whether outstanding
principal, interest, legal fees, and any other amounts owed to the Pledgee by
the Company), the parties hereto shall notify the Escrow Agent to such effect in
writing. Promptly upon receipt of such written notice, the Escrow Agent shall
return to the Pledgor the Transfer Documents and the certificates representing
the Pledged Shares (collectively the "Pledged Materials"), whereupon any and all
rights of Pledgee in the Pledged Materials shall be terminated.

         4. EVENT OF DEFAULT. An "Event of Default" shall be deemed to have
occurred under this Agreement upon an Event of Default as defined in the
Convertible Debentures.

         5. REMEDIES. Upon and anytime after the occurrence of an Event of
Default, the Pledgee shall have the right to provide written notice of such
Event of Default (the "Default Notice") to the Escrow Agent, with a copy to the
Pledgor. As soon as practicable after receipt of the Default Notice, the Escrow
Agent shall deliver to Pledgee the Pledged Materials held by the Escrow Agent
hereunder. Upon receipt of the Pledged Materials, the Pledgee shall have the
right to (i) sell the Pledged Shares and to apply the proceeds of such sales,
net of any selling commissions, to the Obligations owed to the Pledgor by the
Company under the Transaction Documents, including, without limitation,
outstanding principal, interest, legal fees, and any other amounts owed to the
Pledgee, and exercise all other rights and (ii) any and all remedies of a
secured party with respect to such property as may be available under the
Uniform Commercial Code as in effect in the State of New Jersey. To the extent
that the net proceeds received by the Pledgee are insufficient to satisfy the
Obligations in full, the Pledgee shall be entitled to a deficiency judgment
against the Pledgor or the Company for such amount. The Pledgee shall have the
absolute right to sell or dispose of the Pledged Shares in any manner it sees
fit and shall have no liability to the Pledgor, the Company or any other party
for selling or disposing of such Pledged Shares even if other methods of sales
or dispositions would or allegedly would result in greater proceeds than the
method actually used. The Escrow Agent shall have the absolute right to disburse
the Pledged Shares to the Pledgee in batches not to exceed 9.9% of the
outstanding capital of the Company (which limit may be waived by the Pledgee
providing not less than 65 days' prior written notice to the Escrow Agent). The
Pledgee shall return any Pledged Shares released to it and remaining after the
Pledgee has applied the net proceeds to all amounts owed to the Pledgee.

         Each right, power and remedy of the Pledgee provided for in this
Agreement or any other Transaction Document shall be cumulative and concurrent
and shall be in addition to every other such right, power or remedy. The
exercise or beginning of the exercise by the Pledgee of any one or more of the
rights, powers or remedies provided for in this Agreement or any other
Transaction Document or now or hereafter existing at law or in equity or by
statute or otherwise shall not preclude the simultaneous or later exercise by
the Pledgee of all such other rights, powers or remedies, and no failure or
delay on the part of the Pledgee to exercise any such right, power or remedy
shall operate as a waiver thereof. No notice to or demand on the Pledgor in any

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<PAGE>

case shall entitle it to any other or further notice or demand in similar or
other circumstances or constitute a waiver of any of the rights of the Pledgee
to any other further action in any circumstances without demand or notice. The
Pledgee shall have the full power to enforce or to assign or contract is rights
under this Agreement to a third party.

6.       REPRESENTATIONS, WARRANTIES AND COVENANTS.

            6.1. The Pledgor represents, warrants and covenants that:

                 (i) the Pledgor is, and at the time when pledged hereunder will
be, the legal, beneficial and record owner of, and has (and will have) good and
valid title to, all Pledged Shares pledged by the Pledgor hereunder, subject to
no pledge, lien, mortgage, hypothecation, security interest, charge, option or
other encumbrance whatsoever;

                 (ii) the Pledgor has full power, authority and legal right to
pledge all the Pledged Shares pledged by the Pledgor pursuant to this Agreement;
and

                 (iii) all the Pledged Shares have been duly and validly issued,
are fully paid and non-assessable and are subject to no options to purchase or
similar rights.

            6.2. The Pledgor covenants and agrees that it will take all
reasonable steps to defend the Pledgee's right, title and security interest in
and to the Pledged Shares and the proceeds thereof against the claims and
demands of all persons whomsoever (other than the Pledgee and the Escrow Agent);
and the Pledgor covenants and agrees that it will have like title to and right
to pledge any other property at any time hereafter pledged to the Pledgee as
Collateral hereunder and will likewise take all reasonable steps to defend the
right thereto and security interest therein of the Pledgee.

            6.3. The Pledgor covenants and agrees that it will take no action
which would violate or be inconsistent with any of the terms of any Transaction
Document, or which would have the effect of impairing the position or interests
of the Pledgee under any Transaction Document.

            6.4. The Pledgor represents, warrants and covenants that (i) the
Pledgor acquired 16,100,000 shares of Common Stock on March 31, 2004 in exchange
for the Pledgor's shares of Cord Partners, Inc. in connection with a reverse
merger in which the company acquired Cord Partners, Inc., of which 7,770,000
have been pledged to the Pledgee hereunder (ii) the Pledgor has owned its shares
of Cord Partners, Inc. since its inception in January 2003, and (iii) this
Agreement is made with recourse. Upon an Event of Default, the Pledgee shall be
deemed to have acquired the Pledged Shares on the date they were acquired by the
Pledgor. The Pledgor is an "affiliate" of the Company, as such term is defined
in Rule 144(a) promulgated under the Securities Act of 1933, as amended.

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<PAGE>

         7. CONCERNING THE ESCROW AGENT.

            7.1. The Escrow Agent undertakes to perform only such duties as are
expressly set forth herein and no implied duties or obligations shall be read
into this Agreement against the Escrow Agent.

            7.2. The Escrow Agent may act in reliance upon any writing or
instrument or signature which it, in good faith, believes to be genuine, may
assume the validity and accuracy of any statement or assertion contained in such
a writing or instrument, and may assume that any person purporting to give any
writing, notice, advice or instructions in connection with the provisions hereof
has been duly authorized to do so. The Escrow Agent shall not be liable in any
manner for the sufficiency or correctness as to form, manner, and execution, or
validity of any instrument deposited in this escrow, nor as to the identity,
authority, or right of any person executing the same; and its duties hereunder
shall be limited to the safekeeping of such certificates, monies, instruments,
or other document received by it as such escrow holder, and for the disposition
of the same in accordance with the written instruments accepted by it in the
escrow.

            7.3. Pledgee and the Pledgor hereby agree, to defend and indemnify
the Escrow Agent and hold it harmless from any and all claims, liabilities,
losses, actions, suits, or proceedings at law or in equity, or any other
expenses, fees, or charges of any character or nature which it may incur or with
which it may be threatened by reason of its acting as Escrow Agent under this
Agreement; and in connection therewith, to indemnify the Escrow Agent against
any and all expenses, including attorneys' fees and costs of defending any
action, suit, or proceeding or resisting any claim (and any costs incurred by
the Escrow Agent pursuant to Sections 6.4 or 6.5 hereof). The Escrow Agent shall
be vested with a lien on all property deposited hereunder, for indemnification
of attorneys' fees and court costs regarding any suit, proceeding or otherwise,
or any other expenses, fees, or charges of any character or nature, which may be
incurred by the Escrow Agent by reason of disputes arising between the makers of
this escrow as to the correct interpretation of this Agreement and instructions
given to the Escrow Agent hereunder, or otherwise, with the right of the Escrow
Agent, regardless of the instructions aforesaid, to hold said property until and
unless said additional expenses, fees, and charges shall be fully paid. Any fees
and costs charged by the Escrow Agent for serving hereunder shall be paid by the
Pledgor.

            7.4. If any of the parties shall be in disagreement about the
interpretation of this Agreement, or about the rights and obligations, or the
propriety of any action contemplated by the Escrow Agent hereunder, the Escrow
Agent may, at its sole discretion deposit the Pledged Materials with the Clerk
of the United States District Court of New Jersey, sitting in Newark, New
Jersey, and, upon notifying all parties concerned of such action, all liability
on the part of the Escrow Agent shall fully cease and terminate. The Escrow
Agent shall be indemnified by the Pledgor, the Company and Pledgee for all
costs, including reasonable attorneys' fees in connection with the aforesaid
proceeding, and shall be fully protected in suspending all or a part of its
activities under this Agreement until a final decision or other settlement in
the proceeding is received.

            7.5. The Escrow Agent may consult with counsel of its own choice
(and the costs of such counsel shall be paid by the Pledgor and Pledgee) and
shall have full and complete authorization and protection for any action taken
or suffered by it hereunder in good faith and in accordance with the opinion of
such counsel. The Escrow Agent shall not be liable for any mistakes of fact or
error of judgment, or for any actions or omissions of any kind, unless caused by
its willful misconduct or gross negligence.

                                       4

<PAGE>

            7.6. The Escrow Agent may resign upon ten (10) days' written notice
to the parties in this Agreement. If a successor Escrow Agent is not appointed
within this ten (10) day period, the Escrow Agent may petition a court of
competent jurisdiction to name a successor.

            7.7. Conflict Waiver. The Pledgor hereby acknowledges that the
Escrow Agent is general counsel to the Pledgee, a partner in the general partner
of the Pledgee, and counsel to the Pledgee in connection with the transactions
contemplated and referred herein. The Pledgor agrees that in the event of any
dispute arising in connection with this Agreement or otherwise in connection
with any transaction or agreement contemplated and referred herein, the Escrow
Agent shall be permitted to continue to represent the Pledgee and the Pledgor
will not seek to disqualify such counsel and waives any objection Pledgor might
have with respect to the Escrow Agent acting as the Escrow Agent pursuant to
this Agreement.

            7.8. Notices. Unless otherwise provided herein, all demands,
notices, consents, service of process, requests and other communications
hereunder shall be in writing and shall be delivered in person or by overnight
courier service, or mailed by certified mail, return receipt requested,
addressed:

If to the Company, to:              Cord Blood America, Inc.
                                    9000 W. Sunset Boulevard, Suite 4000
                                    Los Angeles, CA 90069
                                    Attention:        Matthew Schissler
                                    Telephone:        (310) 432-4090
                                    Facsimile:        (310) 432-4098

With a copy to:                     Kirkpatrick & Lockhart Nicholson Graham, LLP
                                    201 South Biscayne Boulevard, Suite 2000
                                    Miami, Florida 33131
                                    Attention:        Clayton E. Parker, Esq.
                                    Telephone:        (305) 539-3306
                                    Facsimile:        (305) 328-7095

If to the Pledgee:                  Cornell Capital Partners LP
                                    101 Hudson Street, Suite 3700
                                    Jersey City, NJ 07302
                                    Attention:        Mark A. Angelo
                                    Telephone:        (201) 985-8300
                                    Facsimile:        (201) 985-8744

With copy to:                       Cornell Capital Partners, LP
                                    101 Hudson Street, Suite 3700
                                    Jersey City, NJ 07302
                                    Attention:        David Gonzalez, Esquire
                                    Telephone:        (201) 985-8300
                                    Facsimile:        (201) 985-1964

                                       5

<PAGE>

If to the Pledgor, to:              Cord Blood America, Inc.
                                    9000 W. Sunset Boulevard, Suite 4000
                                    Los Angeles, CA 90069
                                    Attention:        Matthew Schissler
                                    Telephone:        (310) 432-4090
                                    Facsimile:        (310) 432-4098

Any such notice shall be effective (a) when delivered, if delivered by hand
delivery or overnight courier service, or (b) five (5) days after deposit in the
United States mail, as applicable.

         8. BINDING EFFECT. All of the covenants and obligations contained
herein shall be binding upon and shall inure to the benefit of the respective
parties, their successors and assigns.

         9. GOVERNING LAW; VENUE; SERVICE OF PROCESS. The validity,
interpretation and performance of this Agreement shall be determined in
accordance with the laws of the State of New Jersey applicable to contracts made
and to be performed wholly within that state except to the extent that Federal
law applies. The parties hereto agree that any disputes, claims, disagreements,
lawsuits, actions or controversies of any type or nature whatsoever that,
directly or indirectly, arise from or relate to this Agreement, including,
without limitation, claims relating to the inducement, construction, performance
or termination of this Agreement, shall be brought in the state superior courts
located in Hudson County, New Jersey or Federal district courts located in
Newark, New Jersey, and the parties hereto agree not to challenge the selection
of that venue in any such proceeding for any reason, including, without
limitation, on the grounds that such venue is an inconvenient forum. The parties
hereto specifically agree that service of process may be made, and such service
of process shall be effective if made, pursuant to Section 8 hereto.

         10. ENFORCEMENT COSTS. If any legal action or other proceeding is
brought for the enforcement of this Agreement, or because of an alleged dispute,
breach, default or misrepresentation in connection with any provisions of this
Agreement, the successful or prevailing party or parties shall be entitled to
recover reasonable attorneys' fees, court costs and all expenses even if not
taxable as court costs (including, without limitation, all such fees, costs and
expenses incident to appeals), incurred in that action or proceeding, in
addition to any other relief to which such party or parties may be entitled.

         11. REMEDIES CUMULATIVE. No remedy herein conferred upon any party is
intended to be exclusive of any other remedy, and each and every such remedy
shall be cumulative and shall be in addition to every other remedy given
hereunder or now or hereafter existing at law, in equity, by statute, or
otherwise. No single or partial exercise by any party of any right, power or
remedy hereunder shall preclude any other or further exercise thereof.

         12. COUNTERPARTS. This Agreement may be executed in one or more
counterparts, each of which shall be deemed an original, but all of which
together shall constitute the same instrument.

                                       6

<PAGE>

         13. NO PENALTIES. No provision of this Agreement is to be interpreted
as a penalty upon any party to this Agreement.

         14. JURY TRIAL. EACH OF THE PLEDGEE AND THE PLEDGOR HEREBY KNOWINGLY,
VOLUNTARILY AND INTENTIONALLY WAIVES THE RIGHT WHICH IT MAY HAVE TO A TRIAL BY
JURY OF ANY CLAIM, DEMAND, ACTION OR CAUSE OF ACTION BASED HEREON, OR ARISING
OUT OF, UNDER OR IN ANY WAY CONNECTED WITH THE DEALINGS BETWEEN PLEDGEE AND
PLEDGOR, THIS PLEDGE AND ESCROW AGREEMENT OR ANY DOCUMENT EXECUTED IN CONNECTION
HEREWITH, OR ANY COURSE OF CONDUCT, COURSE OF DEALING, STATEMENTS (WHETHER ORAL
OR WRITTEN) OR ACTIONS OF ANY PARTY HERETO OR THERETO IN EACH CASE WHETHER NOW
EXISTING OR HEREAFTER ARISING, AND WHETHER IN CONTRACT, TORT, EQUITY OR
OTHERWISE.

                           [SIGNATURE PAGE TO FOLLOW]

                                        7

<PAGE>

         IN WITNESS WHEREOF, the parties hereto have duly executed this Insider
Pledge and Escrow Agreement as of the date first above written.

                                    CORNELL CAPITAL PARTNERS, LP

                                    By: Yorkville Advisors, LLC
                                    Its: General Partner

                                    By:
                                        --------------------------------
                                    Name:    Mark Angelo
                                    Title: Portfolio Manager

                                    PLEDGOR

                                    Matthew L. Schissler
                                    7,770,000 Shares

                                    ____________________________________

                                   CORD BLOOD AMERICA, INC.

                                   By:
                                   Name: Matthew L. Schissler
                                   Title: Chairman and Chief Executive Officer

                                   ESCROW AGENT

                                   By:
                                        --------------------------------
                                   Name: David Gonzalez, Esq.

         FOR VALUE RECEIVED, the Pledgor hereby unconditionally and absolutely
guarantees the Company's Obligations (as defined above). This Agreement is made
with recourse.

Matthew L. Schissler

_________________________________

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