Document:

Exhibit 4.1

  

   
    

    

    FIRST SUPPLEMENTAL INDENTURE

     

    THIS FIRST SUPPLEMENTAL INDENTURE dated as of January 1, 2022, is by and among UMB Bank, N.A., as Trustee (the “Trustee”), Reliant Bancorp, Inc., a Tennessee corporation (the “Company”), and United Community Banks, Inc., a Georgia corporation (the “Successor Company”), under the Indenture referred to below.

     

    NOW, THEREFORE, in consideration of the premises and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged
      by the parties hereto, the Trustee, the Company, and the Successor Company hereby agree as follows:

     

    PRELIMINARY STATEMENTS

     

    The Trustee and the Company are parties to that certain Indenture, dated as of December 13, 2019, by and between the Company and the Trustee (the “Indenture”), pursuant to which the Company issued $60,000,000 of its Fixed-to Floating Rate Subordinated Notes due 2029 (the “Notes”).

     

    As permitted by the terms of the Indenture, the Company, simultaneously with the effectiveness of this First Supplemental Indenture, shall merge (referred to
      herein for purposes of Article VII of the Indenture as the “Merger”) with and into the Successor Company with the Successor
      Company as the surviving corporation. The parties hereto are entering into this First Supplemental Indenture pursuant to, and in accordance with, Articles VII and VIII of the Indenture.

     

    SECTION 1. Definitions.

     

    All capitalized terms used herein that are defined in the Indenture, either directly or by reference therein, shall have the respective meanings assigned them
      in the Indenture except as otherwise provided herein or unless the context otherwise requires.

     

    SECTION 2. Interpretation.

    

    

    	

          	(a)	
            In this First Supplemental Indenture, unless a clear contrary intention appears:

          

    	

          	(i)	
            a term has the meaning assigned to it;

          

    	

          	(ii)	
            “or” is not exclusive;

          

    	

          	(iii)	
            words in the singular include the plural, and words in the plural include the singular;

          

    	

          	(iv)	
            “including” means including without limitation;

          

    	

          	(v)	
            “will” will be interpreted to express a command;

          

    	

          	(vi)	
            unless the context otherwise requires, any reference to an “Article,” “Section,” or “clause” refers to an Article, Section, or clause, as the case may
              be, of this First Supplemental Indenture; and

          

    	

          	(vii)	
            the words “herein,” “hereof,” and “hereunder” and other words of similar import refer to this First Supplemental Indenture as a whole and not any
              particular Article, Section, clause, or other subdivision.

          

    	

          	(b)	
            No provision in this First Supplemental Indenture shall be interpreted or construed against any Person because that Person or its legal representative
              drafted such provision.

          

     

    SECTION 3. Assumption of Obligations.

    

    

    	

          	(a)	
            Pursuant to, and in compliance and accordance with, Section 7.01 and Section 7.02 of the Indenture, the Successor Company hereby expressly assumes all
              of the obligations of the Company in connection with the Subordinated Notes issued under the Indenture and the performance of every other covenant of the Indenture on the part of the Company.

          

     

      

    

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            	(b)	
              
                
                  Pursuant to, and in compliance and accordance with, Section 7.02 of the Indenture, the Successor Company succeeds to and is
                    substituted for the Company, with the same effect as if the Successor Company had originally been named in the Indenture as the Company.

                

              

            

      

      

    

    SECTION 4. Representations and Warranties.

    

    The Successor Company represents and warrants that (a) it has all necessary power and authority to execute and deliver this First Supplemental Indenture and
      to perform the Indenture, (b) that it is the successor of the Company pursuant to the Merger effected in accordance with applicable law, (c) that it is a corporation organized and validly existing under the laws of the State of Georgia, and (d) that
      this First Supplemental Indenture is executed and delivered pursuant to Article VII and Section 8.01(1) of the Indenture and does not require the consent of any Holder.

    

    

    SECTION 5. Conditions of Effectiveness.

    

    

    This First Supplemental Indenture shall become effective simultaneously with the effectiveness of the Merger, provided, however, that:

    

    

    	

          	(a)	
            the Trustee shall have executed a counterpart of this First Supplemental Indenture and shall have received one or more counterparts of this First
              Supplemental Indenture executed by the Successor Company and the Company;

          

    	

          	(b)	
            the Trustee shall have received an Officers’ Certificate from the Successor Company stating that the Merger complies with Article VII of the Indenture
              and that all conditions precedent provided for in the Indenture relating to the Merger and this First Supplemental Indenture have been complied with;

          

    	

          	(c)	
            the Trustee shall have received an Opinion of Counsel from the Successor Company stating that the Merger complies with Article VII of the Indenture and
              that all conditions precedent provided for in the Indenture relating to the Merger and this First Supplemental Indenture have been complied with; and

          

    	

          	(d)	
            the Successor Company and the Company shall have duly executed and filed articles
                of merger with the Secretary of the State of the State of Tennessee and the Secretary of the State of the State of Georgia in connection with the
              Merger.

          

     

    SECTION 6. Reference to the Indenture.

    

    

    	

          	(a)	
            Upon the effectiveness of this First Supplemental Indenture, each reference in the Indenture to “this Indenture,” “hereunder,” “herein,” or words of
              like import shall mean and be a reference to the Indenture, as affected, amended, and supplemented hereby.

          

    	

          	(b)	
            Upon the effectiveness of this First Supplemental Indenture, each reference in the Subordinated Notes to the Indenture including each term defined by
              reference to the Indenture shall mean and be a reference to the Indenture or such term, as the case may be, as affected, amended, and supplemented hereby.

          

    	

          	(c)	
            The Indenture, as amended and supplemented hereby, shall remain in full force and effect and is hereby ratified and confirmed.

          

     

    SECTION 7. Execution in Counterparts.

     

    This First Supplemental Indenture may be executed in any number of counterparts and by different parties hereto in separate counterparts, each of which, when
      so executed and delivered, shall be deemed to be an original and all of which when taken together shall constitute but one and the same instrument.

    

    

    SECTION 8. Governing Law; Binding Effect.

    

    

    This First Supplemental Indenture shall be governed by and construed in accordance with the laws of the State of New York and shall be binding upon the
      parties hereto and their respective successors and assigns.

     

    

    

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    SECTION 9. The Trustee.

     

    The Trustee shall not be responsible in any manner whatsoever for or in respect of the validity or sufficiency of this First Supplemental Indenture or the due
      execution thereof by the Company or the Successor Company. The recitals of fact contained herein shall be taken as the statements solely of the Company or the Successor Company, and the Trustee assumes no responsibility for the correctness thereof.

     

    [Signatures on following page]

     

    

    

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    IN WITNESS WHEREOF, the parties hereto have caused this First Supplemental Indenture to be duly executed as of the day and year first written above.

     

    

    	 	
            RELIANT BANCORP, INC.

          
	 	 	 
	 	By: 

          	/s/ DeVan D. Ard, Jr. 

          
	 	
            Name:

          	
            DeVan D. Ard, Jr.

          
	 	
            Title:

          	
            Chairman and Chief Executive Officer

          
	 	 
	 	
            UNITED COMMUNITY BANKS, INC.

          
	 	 	 
	 	By:	/s/ H. Lynn Harton
	 	
            Name:

          	
            H. Lynn Harton

          
	 	
            Title:

          	
            President and Chief Executive Officer

          
	 	 
	 	
            UMB BANK, N.A.,

            as Trustee

          
	 	 	 
	 	By:	/s/ Shazia Flores
	 	
            Name:

          	
            Shazia Flores

          
	 	
            Title:

          	
            Vice President

          

    

    

    [Signature Page to First Supplemental Indenture]Exhibit 10.1

 

FIRST
AMENDMENT TO AMENDED AND RESTATED EMPLOYMENT AGREEMENT

 

This First Amendment to Amended
and Restated Employment Agreement (this “Amendment”) is made effective as of January 1, 2022 (the “Amendment
Effective Date”), by and between Aptinyx, Inc. (the “Company”), and Andrew D. Kidd (the “Executive”).

 

WITNESSETH

 

WHEREAS, the Company and the
Executive are parties to an Amended and Restated Employment Agreement effective as of the closing of the Company’s first underwritten
public offering of its equity securities pursuant to an effective registration statement under the Securities Act of 1933 (the “Employment
Agreement”);

 

WHEREAS, the Company and the
Executive wish to amend certain provisions of the Employment Agreement to reflect Executive’s transition into the Company’s
Chief Executive Officer role;

 

WHEREAS, the Executive is
entering into this Amendment in consideration and as a condition of his continued employment;

 

WHEREAS, capitalized terms
used herein and not otherwise defined shall have the meanings ascribed to them in the Employment Agreement.

 

NOW, THEREFORE, in consideration
of the mutual agreements and covenants set forth herein, and for other good and valuable consideration, the receipt and sufficiency of
which are hereby acknowledged, the parties hereto, intending to be legally bound, hereby agree as follows:

 

1.            Section 2
of the Employment Agreement (“Duties”) is hereby amended and restated in its entirety to read as follows:

 

The Executive will serve as President and Chief Executive
Officer and will have such powers and duties as may from time to time be prescribed by the Chairman of the Company’s Board of Directors
(the “Board”). The Executive shall devote his full working time and efforts to the business and affairs of the Company and
not engage in any other business activities without prior written approval by the Board. Notwithstanding the foregoing, the Executive
may engage in religious, charitable or other community activities as long as such services and activities do not interfere with the Executive’s
performance of his duties to the Company.

 

2.            Section 3(a) of
the Employment Agreement (“Base Salary”) is hereby amended by (i) deleting the number “$341,700.00” and replacing
it with “$500,000.00” and (ii) replacing “the Company’s Board of Directors (the “Board”)”
with “the Board.”

 

3.            Section 3(b) of
the Employment Agreement (“Incentive Bonus”) is hereby amended by deleting the percentage “25%” and replacing
it with “50%”.

 

     

     

    

 

4.            Section 5
of the Employment Agreement (“Severance and Accelerated Vesting if a Terminating Event Occurs within the Sale Event Period”)
is hereby amended by (i) deleting the three references to a time period of “12 months” and replacing each such reference
with “18 months” and (ii) deleting the percentage “100%” in Section 5(a) and replacing it with
 “150%”.

 

5.            Section 6
of the Employment Agreement (“Severance if a Terminating Event Occurs Outside the Sale Event Period”) is hereby amended by
deleting the three references to a time period of “9 months” and replacing each such reference with “12 months.”

 

6.            The
Executive and the Company agree and hereby acknowledge that neither the Company’s tendering of this Amendment nor any aspect of
this Amendment taking effect shall constitute an occurrence constituting Good Reason as defined in Section 4 of the Employment Agreement.

 

7.            All
other provisions of the Employment Agreement shall remain in full force and effect according to their respective terms, and nothing contained
herein shall be deemed a waiver of any right or abrogation of any obligation otherwise existing under the Employment Agreement except
to the extent specifically provided for herein.

 

8.            This
Amendment may be executed in counterparts, each of which shall be deemed an original, but all of which together shall constitute one and
the same instrument. Signatures on this Amendment may be conveyed by facsimile or other electronic transmission and shall be binding upon
the parties so transmitting their signatures. Counterparts with original signatures shall be provided to the other parties following the
applicable facsimile or other electronic transmission; provided, that failure to provide the original counterpart shall have no effect
on the validity or the binding nature of this Amendment.

 

[Signature page follows]

 

    2 

     

    

 

IN WITNESS WHEREOF, the parties hereto have executed
this Amendment as of the Amendment Effective Date.

 

	 	THE COMPANY
	 	 
	 	APTINYX, INC.
	 	 
	 	/s/ Ashish Khanna
	 	By:	Ashish Khanna
	 	Its:	Chief Financial Officer and Chief Business Officer
	 	 
	 	THE EXECUTIVE
	 	 
	 	/s/ Andrew D. Kidd
	 	Andrew D. Kidd

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