Document:

Stock Purchase Agreement

 Exhibit 10.43 
 BIOAMBER INC. 
 STOCK PURCHASE AGREEMENT 

THIS STOCK PURCHASE AGREEMENT (this “Agreement”) is made and entered into on February 6th, 2012 (the “Execution Date”) by and among BioAmber
Inc., a Delaware corporation (the “Company”), and Lanxess Corporation, a Delaware corporation (the “Purchaser”). 
 RECITALS 
 WHEREAS, the Company’s Board of Directors has
determined that in order to raise additional funds for the Company’s and its Subsidiaries general corporate purposes, potential asset or other acquisitions and certain other purposes, it is in the best interest of the Company to issue 10,030
shares of the Company’s Common Stock, par value $0.01 per share (“Common Stock”), at a price of US$997.00 per share, on the terms and conditions set forth in this Agreement (the “Financing”); and 

WHEREAS, the Company wishes to issue and sell to the Purchaser, and the Purchaser wishes to purchase from the Company, 10,030
shares of Common Stock on the terms and conditions set forth herein. 
 NOW, THEREFORE, in consideration of the foregoing
recitals and the mutual promises, representations, warranties and covenants hereinafter set forth and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto agree as follows:

 1. Agreement to Purchase and Sell Shares of Common Stock. At the Closing (as defined below), the Company shall sell and issue to the
Purchaser, and, subject to the terms and conditions set forth herein, the Purchaser shall acquire and purchase from the Company, 10,030 Securities (as defined below) upon payment by the Purchaser of a purchase price of Nine Million Nine Hundred
Ninety-Nine Thousand Nine Hundred and Ten US Dollars (US$9,999,910) (the “Purchase Price”), payable as set out in Section 2 of this Agreement. The shares of Common Stock issued to the Purchaser are referred to in this
Agreement as the “Securities.” 
 2. Closing; Delivery and Payment. The closing of the purchase and
sale of the Securities under this Agreement (the “Closing”) shall take place at 5pm New York City time on February 6th, 2012 (the “Closing Date”), subject to the satisfaction (or waiver as provided herein) of the
conditions set forth in Section 6 (other than those conditions that by their nature will be satisfied at the Closing), unless another time or date is agreed to in writing by the parties. This Agreement, the Second Amendment to the
Amended and Restated Shareholders Agreement of the Company attached hereto as Exhibit A (the “Second Amendment”), the three (3) Heads of Agreements attached hereto as Exhibit B (collectively, the “Heads of
Agreement”) and all other agreements, certificates, documents and instruments furnished in connection herewith or therewith at or prior to the Closing are referred to collectively herein as the “Closing Documents”. The
parties agree that the delivery of this Agreement, the Closing Documents and any other documents at the Closing may be effected by means of an exchange of facsimile signatures with original copies to follow by mail or courier service. 

 2.1 At the Closing, subject to the terms and conditions hereof, the Company shall deliver to
the Purchaser the following: 
 (a) a duly executed counterpart to the Second Amendment; 

(b) a duly executed Heads of Agreement; 

(c) a duly executed stock certificate representing the Securities registered in the name of the Purchaser; 

(d) a certificate of good standing as to the Company issued by the Secretary of State of the State of Delaware, dated as
of a date within five (5) business days of the Closing Date; 
 (e) a certificate of good standing as to
each of the Subsidiaries issued by the Secretary of State, or similar governmental authority, in each such Subsidiaries’ jurisdiction of organization, dated as of a date within five (5) business days of the Closing Date; 

(f) a certificate of the secretary of the Company in a form satisfactory to the Purchaser certifying as to (i) the
incumbency of the officers executing the Closing Documents on behalf of the Company, (ii) the resolutions of the Board of Directors and, to the extent required under applicable law, the shareholders, of the Company duly authorizing the
transactions contemplated by this Agreement and the other Closing Documents, and (iii) the Bylaws of the Company as in effect at the time of the Closing, and (iv) the Amended and Restated Certificate of Incorporation of the Company as in
effect at the time of the Closing; 
 (g) a certificate of each of Jean-François Huc, Michael Hartmann and
Jim Millis (the “Key Company Personnel”) pursuant to Section 6.5 hereof; 
 (h)
copies of all consents, waivers and other approvals required in connection with execution, delivery and performance of this Agreement and the other Closing Documents and the other transactions contemplated hereunder and thereunder. 

2.2 At the Closing, subject to the terms and conditions hereof, the Purchaser shall pay the Purchase Price by wire transfer of
immediately available funds to an account designated in writing by the Company not less than two business days prior to the Closing and shall deliver to the Company the following: 

(a) a duly executed counterpart of the Second Amendment; 

(b) a duly executed Heads of Agreement; 

(c) a duly executed Undertaking in the form attached hereto as Exhibit C; and 

(d) a duly executed Accredited Investor Certificate in the form attached hereto as Exhibit D. 

  
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 3. Representations and Warranties. The Company and each of the Key Company Personnel, jointly and
severally, hereby represent and warrant to the Purchaser that the statements contained in this Section 3 are true and correct, except as set forth in the Disclosure Schedules attached to this Agreement (the “Schedules”).
The Schedules shall be arranged in numbered paragraphs and each exception shall be deemed to qualify only the specific numbered section of this Agreement which is referenced in the applicable exception. 

3.1 Subsidiaries. Except as set forth in Schedule 3.1, the Company (a) does not own or control any equity security or
other interest of any other corporation, limited partnership or other business entity and (b) is not a participant in any joint venture, partnership or similar arrangement. As used in this Agreement, the term “Subsidiaries”
shall mean Sinoven Biopolymers, Inc., a Delaware corporation (“Sinoven”), BioAmber S.A.S., a Societe par Actions Simplifiee (“BioAmber”), BioAmber Sarnia Inc., a Canadian Corporation (“BioAmber
Sarnia”), BioAmber International S.à.r.l., a Luxembourg Société a Responsabilité Limitée and the other corporations, limited partnerships, limited liability companies, and other business entities
(including those listed as joint ventures, partnerships or similar arrangements pursuant to (b)) listed (or required to be listed) in Schedule 3.1. The Company owns 100% of the outstanding capital stock of BioAmber and, except as specifically
disclosed in Schedule 3.1, owns 100% of the outstanding capital stock of each of the other Subsidiaries. 
 3.2
Organization, Good Standing and Qualification. 
 (a) The Company and each of its Subsidiaries are duly
organized, validly existing and in good standing under the Laws (as defined in Section 3.15(a)) of their jurisdiction of formation. The Company and each of its Subsidiaries has all requisite corporate power and authority to own and
operate their properties and assets and to carry on their business as currently conducted and as proposed to be conducted. The Company has all requisite corporate power and authority to execute and deliver the Closing Documents to which it is
a party, to issue and sell the Securities and to carry out the provisions of this Agreement and the other Closing Documents. The Company and each of its Subsidiaries are duly qualified and in good standing in all jurisdictions in which (i) the
nature of their activities and of their properties (both owned and leased) makes such qualification necessary, or (ii) the failure to so qualify might reasonably be expected to have a Material Adverse Effect. 

(b) Neither the Company nor any of its Subsidiaries is in violation or default of any term of their respective certificate
of incorporation, bylaws or other organizational documents (“Organizational Documents”). The execution, delivery, and performance of this Agreement and the other Closing Documents by the Company, and the sale, issuance and delivery
of the Securities pursuant hereto will not, with or without the passage of time or giving of notice, result in any such violation, or be in conflict with or constitute a default under the Company’s Organizational Documents. 

3.3 Capitalization. 
 (a) The authorized capital stock of the Company consists of 500,000 shares of Common Stock, 287,679 shares of which are issued and outstanding. Schedule 3.3(a) sets forth a capitalization table of
the Company on a post-closing, as-converted, fully-diluted 

  
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basis. Such capitalization table is complete, accurate and correct and identifies by name and number of securities owned, each stockholder and other holder of the Company’s outstanding
securities. 
 (b) Under the Company’s Stock Incentive Plan, initially adopted on December 8, 2008 (as
amended on November 12, 2009, July 21, 2010, April 15, 2011, June 27, 2011 and December 6, 2011) (the “Plan”), 60,600 shares of Common Stock are available for issuance as of the date hereof,
of which 54,300 shares of Common Stock are subject to options granted and outstanding. Under the Plan, there are no shares reserved but not yet subject to options already granted and outstanding. Some of the options granted pursuant to the Plan will
vest upon an initial public offering of the Company’s shares or a sale/merger transaction involving the Company and some employees have, pursuant to their employment agreements, options that provide for accelerated vesting upon the death of the
employee or the termination of their employment by the Company. Subject to the foregoing, no employee, officer, director or consultant has options or any other securities that provide for accelerated vesting upon termination of employment or
service, merger or change of ownership of the Company or any other event. 
 (c) Other than (i) the shares
reserved for issuance under the Plan, (ii) 41,694 shares reserved for issuance upon the exercise of warrants identified in the capitalization table of the Company set forth in Schedule 3.3(a) and (iii) except as may be granted
pursuant to this Agreement, there are no outstanding options, warrants, rights (including conversion or preemptive rights, rights of first refusal and phantom stock rights), proxy, voting, transfer restriction or stockholder agreements, or
agreements of any kind for the purchase or acquisition from the Company of any of its securities, except for the Amended and Restated Shareholders Agreement of the Company dated as of April 15, 2011, as amended (the “Shareholders
Agreement”). The Closing of the transactions contemplated by this Agreement will not result in (i) accelerated vesting of any options or other equity-based compensation, or (ii) the payment or the obligation of the Company or any of
its Subsidiaries to pay or accelerate the payment of any bonus or other compensation to any employee, consultant, officer, director, or advisor. 
 (d) Other than as set out in the Shareholders Agreement, the Company is not under any obligation, and has not granted any rights, to register any of the Company’s presently outstanding securities or
any of its securities that may hereafter be issued. No stockholder of the Company has entered into any agreement with the Company or, to the Company’s knowledge, any other Person, with respect to the voting or transfer of equity securities of
the Company, except for the Shareholders Agreement. 
 (e) All issued and outstanding shares of the
Company’s capital stock (i) have been duly authorized and validly issued and are fully paid and nonassessable, and (ii) were issued in accordance with all applicable securities Laws, including, without limitation, the registration
requirements of the Securities Act of 1933, as amended (the “Securities Act”), and applicable state securities Laws or pursuant to an exemption from such registration requirements. 

(f) The Securities have been duly and validly reserved for issuance. When issued in compliance with the provisions of this
Agreement, the Securities will be (i)

  
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validly issued, fully paid and nonassessable, (ii) issued in compliance with applicable federal and state securities Laws, and (iii) will be free of any mortgage, pledge, lien,
conditional sale agreement, security agreement, encumbrance or other charge or restriction on transfer of title or voting, whether imposed by agreement, understanding, Law, equity or otherwise (collectively, “Liens”); provided,
however, that the Securities may be subject to restrictions on transfer under applicable state and/or federal securities Laws and the provisions of the Shareholders Agreement. 

(g) Schedule 3.3(g) sets forth a capitalization table of each of the Subsidiaries on an as-converted, fully-diluted
basis. Such capitalization tables identify by name and number of securities owned, each holder of outstanding securities of the Subsidiaries. There are no outstanding options, warrants, rights (including conversion or preemptive rights, rights of
first refusal and phantom stock rights), proxy, voting, transfer restriction or stockholder agreements, or agreements of any kind for the purchase or acquisition from any of the Subsidiaries of any of their securities. None of the Subsidiaries is
under any obligation, nor has any of the Subsidiaries granted any rights, to register any of their presently outstanding securities or any of their securities that may hereafter be issued. All issued and outstanding shares of capital stock and other
equity interests, as applicable, of each of the Subsidiaries have been duly authorized and validly issued and are fully paid and nonassessable and were issued in accordance with all applicable Laws. 

3.4 Authorization; Binding Obligations. All corporate action on the part of the Company, its officers, directors and stockholders
necessary for the authorization of this Agreement and the Closing Documents, the performance of all obligations of the Company hereunder and thereunder and the authorization, sale, issuance and delivery of the Securities has been taken. This
Agreement and the other Closing Documents have been duly executed and delivered by the Company and constitute valid and binding obligations of the Company enforceable in accordance with their respective terms except (a) as limited by applicable
bankruptcy, insolvency, reorganization, moratorium or other Laws of general application affecting enforcement of creditors’ rights, and (b) as limited by general principles of equity that restrict the availability of equitable remedies.

 3.5 Financial Statements. 
 (a) Schedule 3.5(a) attached hereto sets forth the Company’s (i) audited consolidated financial statements for the six-month period ended December 31, 2010 and the period from
June 30, 2009 until June 30, 2010 (the “Consolidated Financial Statements”) and (ii) unaudited consolidated balance sheets as at September 30, 2011 (the “Latest Balance Sheet”) and unaudited
consolidated income statements for the nine month period ending September 30, 2011 (the “Latest Financial Statements” and together with the Consolidated Financial Statements, the “Financial Statements”). The
Financial Statements (including in all cases the notes thereto, if any) fairly present the financial condition, position and operating results of the Company, on a consolidated basis, and have been prepared in accordance with United States generally
accepted accounting principles, as in effect from time to time, consistently applied (“GAAP”) throughout the periods covered thereby. 

  
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 (b) Schedule 3.5(b) attached hereto sets forth the
Subsidiaries’: 
 (i) following financial statements: (x) Sinoven Biopolymers Inc.’s unaudited financial
statements (balance sheet and income statement) for the six month period ended December 31, 2010, and (y) Sinoven Biopolymers Trading (Shanghai) LLC’s (“Sinoven China”) audited financial statements for the period from
August 3, 2010 to December 31, 2010 (the “Subsidiary Financial Statements”); and 
 (ii) unaudited
consolidated balance sheets as of June 30, 2011 for BioAmber SAS and for Sinoven Biopolymers Inc. (the “Subsidiary Latest Balance Sheet”) and unaudited consolidated income statements for the six month period ending
June 30, 2011 for BioAmber SAS and for Sinoven Biopolymers Inc. (the “Subsidiary Latest Financial Statements” and together with the Subsidiary Financial Statements, the “Subsidiary Financial Statements.” The
Subsidiary Financial Statements fairly present the financial condition, position and operating results of such Subsidiaries, and have been prepared in accordance with United States generally accepted accounting principles, as in effect from time to
time, consistently applied (“GAAP”) throughout the periods covered thereby. 
 3.6 Liabilities.

 (a) Except as disclosed on, or reflected or reserved against in, the Consolidated Financial Statements,
neither the Company nor BioAmber Canada have and is not subject to any liability or obligation of any nature, whether accrued, absolute, contingent, or otherwise, asserted or unasserted, known or unknown (including, without limitation, liabilities
as guarantor or otherwise with respect to obligations of others, or liabilities for taxes due or then accrued or to become due), except current liabilities incurred in their ordinary course of business since December 31, 2010 which would not
have a Material Adverse Effect. 
 (b) Except as disclosed on, or reflected or reserved against in, the
Subsidiary Financial Statements, no such Subsidiary has or is subject to any liability or obligation of any nature, whether accrued, absolute, contingent, or otherwise, asserted or unasserted, known or unknown (including, without limitation,
liabilities as guarantor or otherwise with respect to obligations of others, or liabilities for taxes due or then accrued or to become due), except current liabilities incurred in the ordinary course of business of the Subsidiaries since
December 31, 2010 which would not have a Material Adverse Effect. 
 3.7 Agreements. 

(a) Except as set forth in Schedule 3.7(a), there are no agreements, understandings, arrangements or other
commitments, written or oral, to which the Company or any of its Subsidiaries is a party or by which they are bound, (i) that are terminable without the consent of the Company, or (ii) that involve or may involve: 

(i) obligations (contingent or otherwise) of the Company or any of its Subsidiaries, or payments to the Company or any of its
Subsidiaries, in each case in excess of $10,000, 
 (ii) the license of any Intellectual Property (as defined below) by the
Company or any of its Subsidiaries to any third party or by a third party to the Company or any of its Subsidiaries, 

  
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 (iii) provisions restricting or affecting the development, manufacture or distribution of
the products or services of the Company or any of its Subsidiaries, 
 (iv) indemnification by the Company or any of its
Subsidiaries with respect to infringement of proprietary rights, or 
 (v) any other agreement, understanding or instrument to
which the Company or any of its Subsidiaries is a party or by which it is bound that is material to the Company or any of its Subsidiaries. 
 (b) Except as set forth in Schedule 3.7(b), neither the Company nor any of its Subsidiaries is or has ever been a party to, as a contractor or subcontractor, or is making or has ever made, any bid
or proposal with respect to, any government contract. 
 (c) Each agreement, understanding, arrangement or other
commitment which is required to be set forth in Schedule 3.7(a), (each, a “Material Contract”), is in full force and effect and is valid, binding and enforceable in accordance with its terms. The Company has furnished to the
Purchaser complete and correct copies of all such Material Contracts. 
 (d) Neither the Company nor its
Subsidiaries, as applicable, nor any other party is in violation or default under any Material Contract and no event has occurred which with notice, lapse of time or both would constitute a violation default thereunder. The execution, delivery, and
performance of this Agreement and the other Closing Documents by the Company, and the sale, issuance and delivery of the Securities pursuant hereto will not, with or without the passage of time or giving of notice, result in any such violation, or
be in conflict with or constitute a default under any Material Contract. 
 3.8 Obligations to Related Parties. Except as
set forth in Schedule 3.8, neither the Company nor any of its Subsidiaries has any obligations to the officers, directors, stockholders or employees of the Company or any of its Subsidiaries other than for (a) payment of salary for
services rendered, (b) reimbursement for reasonable expenses incurred on behalf of the Company or any of its Subsidiaries and (c) other standard employee benefits made generally available to all employees (including the issuance of stock
options pursuant to the Plan and outstanding warrants). None of the officers, directors or stockholders of the Company or any of its Subsidiaries, or any members of their immediate families, are indebted to the Company or any of its Subsidiaries or,
to the Company’s knowledge, have any direct or indirect ownership interest in any firm or corporation with which the Company or any of its Subsidiaries is affiliated or with which the Company or any of its Subsidiaries has a business
relationship, or any firm or corporation which competes with the Company or any of its Subsidiaries, other than passive investments in publicly traded companies (representing less than one percent of such company) which may compete with the Company
or any of its Subsidiaries. No officer or director of the Company or any of its Subsidiaries or member of their immediate families or, to the Company’s knowledge, any stockholder or key employee, is, directly or indirectly, interested in any
Material Contract or are otherwise indebted to the Company or any of its Subsidiaries. Neither the Company nor any of its Subsidiaries is a guarantor or indemnitor of any indebtedness of any other individual, partnership, limited liability company,
corporation, association, joint stock 

  
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company, trust, joint venture, unincorporated organization, investment fund or other business or governmental entity (“Person”). For purposes of this Agreement, the phrases
“knowledge of the Company” or “the Company’s knowledge” or words of similar import, mean the knowledge of any director, officer, or key employee of the Company or any of its Subsidiaries (including, without
limit, the Key Company Personnel), including facts of which directors, officers, and/or key employees, in the reasonably prudent exercise of their duties, should be aware. 
 3.9 Changes. Except as described on Schedule 3.9, since December 31, 2010, there has not been: 
 (a) Any event that has had or could reasonably be expected to adversely affect the financial condition, business, results of operations or prospects of the Company or any of its Subsidiaries in any
material manner; 
 (b) Any resignation or termination of any officer, key employee or group of employees of the
Company or any of its Subsidiaries, and the Company, to its knowledge, does not know of the impending resignation or termination of employment of any such officer or key employee; 

(c) Any damage, destruction or loss, whether or not covered by insurance, with respect or affecting the properties,
business, assets or prospects or financial condition of the Company or any of its Subsidiaries; 
 (d) Any waiver
or compromise by the Company or any of its Subsidiaries of a valuable right or of a material debt owed to them; 

(e) Any loans made by the Company or any of its Subsidiaries to any stockholder, employee, officer or director of the
Company or any of its Subsidiaries, other than advances made in the ordinary course of business; 
 (f) Any
material change in any compensation arrangement or agreement with any employee, officer, director or stockholder of the Company or any of its Subsidiaries; 
 (g) Any declaration or payment of any dividend or other distribution of the assets of the Company or any of its Subsidiaries; 

(h) Any labor organization activity related to the Company or any of its Subsidiaries; 

(i) Any debt incurred, assumed or guaranteed by the Company or any of its Subsidiaries, except those for immaterial
amounts and for current liabilities incurred in the ordinary course of business; 
 (j) Any sale, mortgage,
pledge, license, transfer, lease or other assignment of any Intellectual Property (as defined below) owned or licensed by the Company or any of its Subsidiaries, other than those listed under Schedule 3.11(d); 

  
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 (k) Any material change in any Material Contract; 

(l) Any sale, mortgage, pledge, transfer, lease or other assignment of any of the tangible assets of the Company or any of
its Subsidiaries outside of the ordinary course of business; 
 (m) Any capital expenditure by the Company or any
of its Subsidiaries in excess of $10,000; 
 (n) to the Company’s knowledge, any other event or condition of
any character that would reasonably be expected to materially and adversely affect the assets, properties, financial conditions, operating results or business of the Company or its Subsidiaries (as such business is presently conducted and as it is
presently proposed to be conducted); or 
 (o) Any arrangement or commitment by the Company or any of its
Subsidiaries to do any of the acts described in subsection (a) through (n) above. 
 3.10 Real and Personal
Property. 
 (a) Real Property. Neither the Company nor any of its Subsidiaries owns or has ever owned
any real property. All of the real property leased by the Company or any of Subsidiaries (the “Leased Real Property”) is identified on Schedule 3.10(a) attached hereto. The schedule of Leased Real Property set forth in
Schedule 3.10(a) is a complete, accurate, and correct list of the Leased Real Property of the Company and its Subsidiaries. Each of the leases for the Leased Real Property set forth on Schedule 3.10(a) (the “Leases”)
is in full force and effect and has not been modified, amended, or altered, in writing or otherwise. Neither the Company nor any of its Subsidiaries nor any other party thereto is in default under any of the Leases, nor has any event occurred which,
with the giving of notice or the passage of time, or both, would give rise to a default. The Company has furnished to the Purchaser complete and correct copies of all Leases and other agreements relating to the Leased Real Property. 

(b) Personal Property. The Company and its Subsidiaries are the sole, legal and equitable owners of all their
respective personal property and assets and have good and marketable title thereto. All such personal property and assets are in good working condition. None of such personal property or assets is subject to any Lien. The Financial Statements
reflect all personal property and assets of the Company and BioAmber Canada (other than assets disposed of in the ordinary course of business since December 31, 2010), and such properties and assets are sufficient for the Company and BioAmber
Canada to conduct their businesses as currently conducted and as proposed to be conducted. The Subsidiary Financial Statements reflect all personal property and assets of such Subsidiaries (other than assets disposed of in the ordinary course of
business since December 31, 2010), and such properties and assets are sufficient for the Subsidiaries to conduct their businesses as currently conducted and as proposed to be conducted. 

  
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 3.11 Intellectual Property. Unless otherwise set forth in Schedule 3.11:

 (a) The Company and its Subsidiaries own, or are licensed or otherwise possess enforceable rights to use, all
Intellectual Property (as defined below) used in or necessary for the conduct of their respective businesses as currently conducted and as proposed to be conducted. There are no claims or demands pending by any other Person pertaining to any of such
Intellectual Property nor, to the knowledge of the Company, is there a claim or demand threatened, and no proceedings have been instituted or, to the knowledge of the Company, threatened which challenge the rights of the Company or any of its
Subsidiaries with respect to such Intellectual Property. 
 (b) With respect to Intellectual Property that is
owned by the Company or its Subsidiaries, all such Intellectual Property is owned free and clear of Liens. All patents, patent applications, trademarks, trademark applications, trademark registrations, service marks, service work applications,
service mark registrations, and registered copyrights which are owned by the Company or its Subsidiaries are listed in Schedule 3.11(b). All such patents, patent applications, trademarks, trademark registrations, trademark applications, and
registered copyrights have been duly registered in, filed in or issued by the United States Patent and Trademark Office, the United States Register of Copyrights, or the corresponding offices of other jurisdictions as identified on Schedule
3.11(b), and have been properly maintained and renewed in accordance with all applicable provisions of Law and administrative regulations of the United States and each such jurisdiction. 

(c) All licenses or other agreements under which the Company or its Subsidiaries are granted rights in Intellectual
Property of any third Person are listed in Schedule 3.11(c). All such licenses or other agreements are in full force and effect and there is no default or threatened default by the Company or any of its Subsidiaries or by any other party
thereto. The licensors under said licenses and other agreements have and, at the time of the grant of such licenses or agreements, had all requisite power and authority to grant the rights purported to be conferred thereby. The execution, delivery,
and performance of this Agreement and the other Closing Documents by the Company, and the sale, issuance and delivery of the Securities pursuant hereto and pursuant to the Company’s Organizational Documents, will not, with or without the
passage of time or giving of notice, impair or otherwise affect the rights of the Company or its Subsidiaries under any such license or agreement. 
 (d) All licenses or other agreements under which the Company or any of its Subsidiaries have granted rights to others in its Intellectual Property are listed in Schedule 3.11(d). All such licenses
or other agreements are in full force and effect and there is no default by the Company or its Subsidiaries or by any other party thereto. The execution, delivery, and performance of this Agreement and the other Closing Documents by the Company, and
the sale, issuance and delivery of the Securities pursuant hereto and pursuant to the Company’s Organizational Documents, will not, with or without the passage of time or giving of notice, impair or otherwise affect the rights of the Company or
its Subsidiaries under any such license or agreement. 
 (e) The Company and its Subsidiaries have taken all
commercially reasonable measures required to establish and preserve their ownership of all Intellectual Property developed by, on behalf of, or licensed to, the Company or any of its Subsidiaries. The Company and its Subsidiaries have required all
current and former employees and all 

  
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consultants and independent contractors having access to, or who were involved in the development of, any of the Intellectual Property owned or developed by the Company or any of its
Subsidiaries, to execute enforceable agreements that provide valid written assignment of all inventions and developments conceived or created by them in the course of their employment or services, and all such Persons are in compliance with such
agreements. The Company has no knowledge of any infringement by others of any of its Intellectual Property. The Company does not believe it is or will be necessary to use any inventions of any of its employees (or persons it intends to hire) made
prior to their employment by the Company or any of its Subsidiaries. All current and former employees and all consultants and independent contractors hired by the Company or any of its Subsidiaries have agreed to maintain the confidentiality of all
confidential and proprietary information of the Company and its Subsidiaries and of any information of third parties received by the Company or any of its Subsidiaries under an obligation of confidentiality. To the knowledge of the Company, no
current or former employee, officer, consultant or contractor is in default or breach of any term of any employment, consulting or contractor agreement, non-disclosure agreement, assignment agreement, or similar agreement. No present or former
employee, officer, consultant or contractor of the Company has any ownership, license or other right, title or interest, directly or indirectly, in whole or in part, in any Intellectual Property that is owned or purported to be owned by the Company
or its Subsidiaries. 
 (f) Neither the Company nor any of its Subsidiaries has infringed, does infringe and, by
conducting its respective business as currently conducted or as proposed to be conducted, will infringe or unlawfully or wrongfully use the Intellectual Property of any third Person. No proceeding charging the Company or any of its Subsidiaries with
infringement of any Intellectual Property of any third Person has been filed or, to the Company’s knowledge, is threatened to be filed. There exists no unexpired patent or, to the Company’s knowledge, patent application which includes
claims that would be infringed by or otherwise adversely affect the products, activities, or business of the Company or any of its Subsidiaries as currently conducted or as proposed to be conducted. 

(g) Neither the Company nor any of its Subsidiaries is making unauthorized use of any confidential information or trade
secrets of any Person, including without limitation, any former employer of any past or present employee of the Company or any of its Subsidiaries. Neither the Company, any of its Subsidiaries nor any employee of the Company or any of its
Subsidiaries is obligated under any duty or agreement (including any license, confidentiality agreement, covenant or commitment of any nature), or subject to any judgment, decree or order of any court or administrative agency, that would interfere
in any manner with the use of their best efforts to promote the interests of the Company or its Subsidiaries or that would conflict with the business as now conducted or proposed to be conducted of the Company or any of its Subsidiaries. Each
current employee, officer and consultant of the Company and its Subsidiaries has executed a proprietary information and assignment of inventions agreement. No employee or consultant is in violation of any proprietary information or assignment of
inventions agreement, or in any such similar agreement, with any former employer or contractor, and the carrying on of the Company’s or its Subsidiaries’ businesses and the conduct of the Company’s and its Subsidiaries’
businesses as proposed will not conflict with or result in a breach of the terms, conditions or provisions of, or constitute a default under, such agreements. 

  
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 (h) As used in this Agreement, the term “Intellectual
Property” means (i) inventions (whether or not patentable), trade secrets, technical data, databases, customer lists, designs, tools, methods, processes, technology, ideas, know how and other confidential or proprietary information and
materials; (ii) trade marks and service marks (whether or not registered), applications for trade marks and service marks, trade names, logos, trade dress and other proprietary indicia and all goodwill associated therewith;
(iii) documentation, advertising copy, marketing materials, specifications, mask works, drawings, graphics, databases, recordings and other works of authorship, whether or not protected by copyright; (iv) source code, object code, data and
operating files, user manuals, documentation, flow charts, algorithms, compilers, development tools, maintenance records and other materials related to computer programs; (v) internet web-sites and domain names; and (vi) all forms of legal
rights and protections that may be obtained for, or may pertain to, the Intellectual Property set forth in clauses (i) through (v) in any country of the world, including, without limitation, all letters patent, patent applications,
provisional patents, design patents, PCT filings and other rights to inventions or designs, all registered and unregistered copyrights in both published and unpublished works, trade secret rights, mask works, moral rights or other literary property
or authors rights, rights regarding trademarks and other proprietary indicia, and all applications, registrations, issuances, divisions, continuations, renewals, reissuances and extensions of the foregoing. 

3.12 Litigation. There is no litigation, arbitration, mediation or proceeding or investigation (each an “Action”
and collectively, “Actions”) pending or, to the knowledge of the Company, threatened against the Company or any of its Subsidiaries or affecting any of their properties or assets or against any officer, director, or key employee of
the Company or any of its Subsidiaries in his or her capacity as an officer, director or employee of the Company or any its Subsidiaries, or which may call into question the validity or hinder the enforceability of this Agreement or any other
Closing Document or the transactions contemplated hereby and thereby; nor has there occurred any event nor does there exist any condition on the basis of which any such Action might be properly instituted or commenced. There are no Actions pending
or, to the Company’s knowledge, threatened relating to the prior employment of any of the Company’s or its Subsidiaries’ employees or consultants, such employees’ or consultants’ use in connection with the Company’s or
its Subsidiaries’ business of any information, technology or techniques allegedly proprietary to any of such employees’ or consultants’ former employers, clients or other parties, or such employees’ or consultants’
obligations under any agreements with prior employers, clients or other parties. Neither the Company nor any of its Subsidiaries is a party or subject to the provisions of any order, writ, injunction, judgment or decree of any court or government
agency or instrumentality. There is no Action by the Company or any of its Subsidiaries pending or threatened against others. 

3.13 Tax Returns and Payments. The Company and each of its Subsidiaries have filed on a timely basis all tax returns and reports
as required by any applicable Laws. Such tax returns and reports correctly and completely reflect the liability for taxes and all other information required to be reported thereon by the Company and its Subsidiaries. The Company and each of its
Subsidiaries have paid all taxes and other assessments due to be paid before the Closing. The Company and each of its Subsidiaries have adequately provided for, in its books of account and related records, liability for all unpaid taxes, being
current taxes not yet due and payable. Neither the Company nor any of its Subsidiaries have been advised that any of their 

  
 12 

 
federal, state or other returns have been or are being audited, or of any deficiency in assessment in its federal, state or other taxes. All taxes and other assessments and levies which the
Company or any of its Subsidiaries are required to withhold or collect have been withheld and collected and have been paid over to the proper governmental authorities. 
 3.14 Employees. 
 (a) Neither the Company nor any of its
Subsidiaries maintains or contributes to any employee benefit plan, pension plan, stock option, bonus or incentive plan, severance pay policy or agreement, deferred compensation agreement, or any similar plan or agreement (an “Employee
Benefit Plan”) other than the Employee Benefit Plans identified in Schedule 3.14. No other corporation, trade, or business exists which would be treated together with the Company or any of its Subsidiaries as a single
“employer” under the provisions of Section 414(b), (c), (m) or (o) of the Internal Revenue Code of 1986, as amended (the “Code”). Each Employee Benefit Plan has been and is currently administered in
compliance with its constituent documents and all reporting, disclosure and other requirements of the Employee Retirement Income Security Act of 1974, as amended (“ERISA”), and the Code and any other Law applicable to such Employee
Benefit Plan. There are no unfunded obligations of the Company or any of its Subsidiaries under any retirement, pension, profit-sharing, deferred compensation plan or similar program, and any employee contributions withheld from payroll have been
timely and fully contributed to the appropriate Employee Benefit Plan as required under applicable Law. Neither the Company nor any of its Subsidiaries is required to make any payments or contributions to any Employee Benefit Plan pursuant to any
collective bargaining agreement or any applicable labor relations Law. Neither the Company nor any of its Subsidiaries has ever maintained or contributed to any Employee Benefit Plan providing or promising any health or other nonpension benefits to
terminated employees (other than continuation coverage, at the maximum applicable premium permitted to be charged by the Company, required under Section 4980B of the Code, or Section 601 of the ERISA). 

(b) Schedule 3.14(b) sets forth a list of (a) all members of the management team of the Company and the
Subsidiaries, together with each such person’s position, date of hiring, salary and any other compensation payable to such person (including, without limitation, compensation payable pursuant to bonus, deferred compensation or commission
arrangements), and (b) each contract, commitment, arrangement, or understanding, whether oral or written, relating to the employment of, or the performance of services by, any employee, consultant, or independent contractor. Neither the Company
nor any of its Subsidiaries is delinquent in payments to any of their employees for any wages, salaries, commissions, bonuses or other direct compensation for any services performed for them to the date hereof or amounts required to be reimbursed to
such employees. The Company and each of its Subsidiaries are in compliance with all applicable Laws, agreements, orders, and consent decrees respecting labor, employment, immigration, fair employment practices, terms and conditions of employment,
and wages and hours. Neither the Company nor any of its Subsidiaries has any collective bargaining agreements with any of their employees. There is no labor union organizing activity pending or, to the Company’s knowledge, threatened with
respect to the Company or any of its Subsidiaries. There are no charges of employment discrimination or unfair labor practices or any strikes, slowdowns, stoppages of work, or any other concerted interference with normal operations, pending or, to
the knowledge of the Company, threatened against or involving the Company or any of its Subsidiaries. 

  
 13 

 (c) No employee of the Company or any of its Subsidiaries, nor any
consultant with whom the Company or any of its Subsidiaries has contracted, is in violation of any term of any employment contract, proprietary information agreement or any other agreement relating to the right of any such individual to be employed
by, or to contract with, the Company or its Subsidiaries because of the nature of the business conducted by the Company or any of its Subsidiaries; and to the Company’s knowledge, the continued employment by the Company and its Subsidiaries of
their present employees, and the performance of the contracts with their independent contractors, will not result in any such violation. Neither the Company nor any of its Subsidiaries has received any notice alleging that any such violation has
occurred. Except as disclosed on Schedule 3.14(c), no employee of the Company or any of its Subsidiaries has been granted the right to continued employment by the Company or any of its Subsidiaries or to any material compensation following
termination of employment with the Company or its Subsidiaries. To the Company’s knowledge, no officer, key employee or group of employees intends to terminate his, her or their employment with the Company or its Subsidiaries, nor does the
Company or its Subsidiaries have a present intention to terminate the employment of any officer, key employee or group of employees. 
 (d) Each Employee Benefit Plan has been administered and operated in compliance with Section 409A of the Code and neither the Company nor any Subsidiary has any obligations to employees or other
service providers with respect to any deferred compensation plan, agreement, method, or arrangement which might be subject to an excise tax under Section 409A of the Code. 

3.15 Compliance with Laws; Authorizations. 

(a) The Company and each of its Subsidiaries have complied with each, and are not in violation of, any law, statute,
regulation, rule, ordinance or order (collectively, “Laws”) to which the Company or any of its Subsidiaries or their businesses, operations, employees, assets or properties are or have been subject, including but not limited to any
Laws which apply to the manufacture, distribution and/or export of succinic acid, modified PBS and other related polymers and/or formulations thereof. No event has occurred or circumstances exist that (with or without the passage of time or the
giving of notice) may result in a violation of, conflict with or failure on the part of the Company or any of its Subsidiaries to comply with, any Law. Neither the Company nor any of its Subsidiaries has received notice regarding any violation of,
conflict with, or failure to comply with, any Law. The execution, delivery, and performance of this Agreement and the other Closing Documents by the Company, and the sale, issuance and delivery of the Securities pursuant hereto will not, with or
without the passage of time or giving of notice, result in any such violation, or be in conflict with or constitute a default under any Law. 
 (b) The Company and each of its Subsidiaries owns, holds, possesses or lawfully uses in the operation of their respective business all franchises, licenses, permits and registrations (collectively,
“Authorizations”) which are required or otherwise necessary for them to conduct their business as currently conducted or as proposed to be conducted or for the 

  
 14 

 
ownership and use of the assets owned or used by them in the conduct of their business, free and clear of all Liens. Such Authorizations are valid and in full force and effect and none of such
Authorizations will be terminated or impaired or become terminable as a result of the transactions contemplated by this Agreement or the other Closing Documents. All Authorizations are listed in Schedule 3.15(b). No event has occurred or
circumstances exist that (with or without the passage of time or the giving of notice) may result in a violation of, conflict with, failure on the part of the Company or any of its Subsidiaries to comply with the terms of, or the revocation,
withdrawal, termination, cancellation, suspension or modification of any Authorization. Neither the Company nor any of its Subsidiaries has received notice regarding any violation of, conflict with, failure to comply with the terms of, or any
revocation, withdrawal, termination, cancellation, suspension or modification of, any Authorization. Neither the Company nor any of its Subsidiaries is in default or has received notice of any claim of default, with respect to any Authorization.

 3.16 Environmental. 
 (a) Except as set forth on Schedule 3.16: (i) the Company and its Subsidiaries are and have been in compliance with all Environmental Laws; (ii) neither the Company nor any of its
Subsidiaries has received any notice alleging that they are not in such compliance with Environmental Laws; (iii) there has been no unpermitted treatment, storage, disposal or release of any pollutant, contaminant or toxic or hazardous
material, substance or waste, or petroleum or any fraction thereof, (each a “Hazardous Substance”) on, upon, into or from any site currently or heretofore owned, leased or otherwise used by the Company or its Subsidiaries which
release could reasonably be expected to give rise to any liability of the Company or its Subsidiaries; (iv) no Hazardous Substances are present in, on, about or migrating to or from any real property that could be expected to give rise to an
action under Environmental Laws against the Company or its Subsidiaries; (v) there have been no Hazardous Substances generated by the Company or its Subsidiaries that have been disposed of at any site that has been included in any published
U.S. federal, state or local “superfund” site list or any other similar list of hazardous or toxic waste release sites published by any governmental authority in or outside of the United States; and (vi) there are no underground
storage tanks located on, no polychlorinated biphenyls (“PCBs”) or PCB-containing equipment used or stored on, and no hazardous waste as defined by the Resource Conservation and Recovery Act, as amended, stored on, any site owned or
operated by the Company or its Subsidiaries, except for any of the foregoing in compliance with Environmental Laws. For purposes of this Section 3.16, “Environmental Laws” means any law, regulation, or other applicable
requirement relating to (i) releases or threatened release of Hazardous Substance; (ii) pollution or protection of employee health or safety, public health or the environment; or (iii) the manufacture, handling, transport, use,
treatment, storage, or disposal of Hazardous Substances. The Company and each of its Subsidiaries have obtained, and are in compliance with, all Authorizations required by any Environmental Laws. All such Authorizations are valid and in full force
and effect and none of such Authorizations will be terminated or impaired or become terminable as a result of the transactions contemplated by this Agreement or the other Closing Documents. The Company and each of its Subsidiaries have been, and are
currently, in compliance with all Environmental Laws. 

  
 15 

 (b) There are no past, pending or, to the Company’s knowledge,
threatened actions against or affecting the Company or any of its Subsidiaries under any Environmental Law, and the Company is not aware of any facts or circumstances which could be expected to form the basis for any such action against the Company
or any of its Subsidiaries. 
 (c) The Company has provided to the Purchaser true and complete copies of, or
access to, all written environmental assessments, materials, reports, data, analyses and compliance audits that have been prepared by or on behalf of the Company or any of its Subsidiaries. 

3.17 Offering Valid. Assuming the accuracy of the representations and warranties of the Purchaser contained in
Section 4.2 hereof, the offer, sale, issuance and delivery of the Securities will be exempt from the registration requirements of the Securities Act, and will have been registered or qualified (or are exempt from registration and
qualification) under the registration, permit or qualification requirements of all applicable state securities Laws. 
 3.18
Insurance. The Company and each of its Subsidiaries has fire, casualty, product liability, and business interruption and other insurance policies, with extended coverage, sufficient in amount to allow it to replace any of its material
properties which might be damaged or destroyed or sufficient to cover liabilities to which the Company and its Subsidiaries may reasonably become subject, and such types and amounts of other insurance with respect to its business and properties, on
both a per occurrence and an aggregate basis, as are customarily carried by Persons engaged in the same or similar businesses as the Company and its Subsidiaries. There is no default by the Company or any of its Subsidiaries, or to the knowledge of
the Company, by any insurance carrier of such policies, or event which could give rise to a default under any such policy. 

3.19 Corporate Documents. The Amended and Restated Certificate of Incorporation of the Company and Bylaws of the Company are in
the form provided to the Purchaser. The Company has made available to the Purchaser the minute books of the Company and its Subsidiaries containing minutes of the material meetings of directors and stockholders and the material actions by written
consent without a meeting by the directors and stockholders since the date of the Company’s or such Subsidiary’s incorporation. 
 3.20 No Brokers. No agent, broker, investment banker, person or firm acting on behalf of or under the authority of the Company or its Subsidiaries is or will be entitled to any broker’s or
finder’s fee or any other commission directly or indirectly in connection with the transactions contemplated by this Agreement. The Company shall pay, and hold the Purchaser harmless against, any liability, loss or expense (including, without
limitation, attorneys’ fees and out-of-pocket expenses) arising in connection with any claim for any such fee or commission. 
 3.21 Disclosure. The representations and warranties made or contained in this Agreement, the schedules and exhibits hereto, and the certificates and statements executed or delivered in connection
herewith, when taken together, do not and shall not contain any untrue statement of a material fact and do not and shall not omit to state a material fact required to be stated therein or necessary in order to make such representations, warranties,
or other material 

  
 16 

 
not misleading in light of the circumstances in which they were made or delivered. There have been no events or transactions, or facts or information which have not been disclosed herein or in a
schedule hereto which have or could reasonably be expected to adversely affect the financial condition, business, results of operations or prospects of the Company or any of its Subsidiaries in any material manner. All references in this
Section 3 to documents being made available to the Purchaser are references to the documents having been posted and made accessible to the Purchaser or otherwise delivered to and received by the Purchaser prior to the date of this Agreement in
the Company’s data room located at https://virtualdataroom.bio-amber.com. The copies of the documents in the Company’s data room are true and correct. 
 4. Representations and Warranties of the Purchaser. The Purchaser hereby represents and warrants to the Company that the statements contained in this Section 4 are true and correct.

 4.1 Requisite Power and Authority. The Purchaser has all necessary power and authority to execute and deliver this
Agreement and the other Closing Documents and to carry out their provisions. All action on the Purchaser’s part required for the execution and delivery of this Agreement and the other Closing Documents has been taken. Upon its execution and
delivery, this Agreement and the other Closing Documents will be valid and binding obligations of the Purchaser, enforceable in accordance with their respective terms, except (a) as limited by applicable bankruptcy, insolvency, reorganization,
moratorium or other Laws of general application affecting enforcement of creditors’ rights, and (b) as limited by general principles of equity that restrict the availability of equitable remedies. 

4.2 Investment Representations. The Purchaser is purchasing the Securities for its own account and not with a view to the resale,
distribution or other disposition thereof in violation of the registration requirements of U.S. securities laws. The Purchaser is an “accredited investor” that meets one or more of the criteria in Rule 501(a) of Regulation D under the
Securities Act and is authorized to consummate the purchase of the Securities. Purchaser acknowledges (a) that the offer and sale of the Securities have not been registered under the Securities Act or the securities Laws of any state or other
jurisdiction (b) that the Securities are being offered and sold pursuant to an exemption from registration under the Securities Act provided by Section 4(2) of Securities Act, and exemptions under applicable state securities Laws; and
(c) that the Securities will be “restricted securities” as defined in Rule 144(a)(3) under the Securities Act and cannot be disposed of unless they are subsequently registered under the Securities Act and any applicable state Laws or
the Purchaser has furnished to the Company an opinion of counsel of recognized standing or other evidence reasonably satisfactory to the Company to the effect that the proposed transfer may be made without registration under the Securities Act and
any applicable state securities Laws. The foregoing, however, does not limit or modify the representations and warranties of the Company in this Agreement or the right of the Purchaser to rely thereon. Purchaser understands and agrees that the
Securities will bear a legend substantially similar to the legend set forth below in addition to any other legend that may be required by applicable Law or by the Company’s Organizational Documents, as the same may be amended from time to time,
or by any agreement between the Company and Purchaser: 
 THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED
UNDER THE SECURITIES ACT OF 1933, AS AMENDED, AND APPLICABLE STATE SECURITIES LAWS, 

  
 17 

 
AND MAY NOT BE OFFERED, SOLD OR OTHERWISE TRANSFERRED, PLEDGED OR HYPOTHECATED UNLESS AND UNTIL SUCH SECURITIES ARE REGISTERED UNDER SUCH ACT, AND APPLICABLE STATE SECURITIES LAWS, OR AN OPINION
OF COUNSEL REASONABLY SATISFACTORY TO THE COMPANY IS OBTAINED TO THE EFFECT THAT SUCH REGISTRATIONS ARE NOT REQUIRED. 
 The Purchaser
acknowledges and agrees that it is not purchasing Securities as a result of “general solicitation” or “general advertising”, as such terms are defined in Regulation D under the Securities Act. 

If the Purchaser is acquiring any Securities as a fiduciary or agent for one or more investor accounts, it represents that it has full power to make the
foregoing representations, warranties and agreements on behalf of each such account and that the foregoing representations, warranties and agreements are true and correct and will be binding upon each such account. 

5. Additional Covenants of the Company. The Company hereby covenants that, so long as any obligation of the Company under the Closing Documents is
outstanding or as long as Purchaser or any affiliate of Purchaser continues to own any of the Securities, the Company shall comply with the following affirmative covenants: 
 5.1 Information; Inspection Rights. 
 (a) Information. From and
after the Closing, the Company shall deliver to the Purchaser the following: 
 (i) Material Threat. Within fifteen
(15) days after the Company or any of its Subsidiaries obtains knowledge of the commencement or written threat of commencement of any material litigation or proceeding against the Company or any of its Subsidiaries or their respective assets,
written notice by the Company of the nature and extent of such litigation or proceeding. 
 (ii) Default. Within ten
(10) days after the occurrence of any default by the Company or any of its Subsidiaries, or any notice of default or potential default or similar material adverse development with respect to the Company or any of its Subsidiaries, furnish the
Purchaser with a detailed written notice of such event. 
 (iii) Stockholder Notices and Consents. Promptly, all notices
for and minutes of meetings of the stockholders or directors of the Company or any of its Subsidiaries, and all written consents taken by the stockholders or directors of the Company or any of its Subsidiaries. 

(iv) Subsidiaries’ Notices. Promptly, all notices received by the Company in its capacity as a shareholder of any of the
Subsidiaries. 
 (v) Material Developments. Within ten (10) days after the occurrence thereof, detailed written
notice of all material developments and of all transactions outside of the 

  
 18 

 
ordinary course of business that have or might have a significant effect on the results of operations, financial condition, business, or prospects of the Company or any of its Subsidiaries or on
each Purchaser’s interest in the Securities. 
 (vi) Additional Information. From time to time, and promptly, such
additional information and financial data regarding results of operations, financial condition, business, affairs or prospects of the Company or any of its Subsidiaries, which the Purchaser may reasonably request, including, without limitation, a
list of stockholders and other security holders, showing the authorized and outstanding shares by class (including the common stock equivalents of any convertible security), the holdings of each stockholder (both before giving effect to dilution and
on a fully-diluted basis) and the holdings of each Person that holds options, warrants or convertible securities (both before giving effect to dilution and on a fully diluted basis). Such information shall be delivered to Purchaser without regard to
the purpose of such request and Purchaser shall have no obligation to demonstrate that the purpose of such request is proper or reasonably related to its investment under any applicable Law. 

(b) Inspection Rights. At such reasonable times and as often as may be reasonably requested, the Purchaser, or any
authorized representative thereof, shall have the right to (i) visit and inspect any of the properties of the Company and its Subsidiaries, (ii) examine the corporate and financial records (and make copies thereof or extracts therefrom) of
the Company and its Subsidiaries, (iii) discuss the business, affairs, finances and accounts of the Company and its Subsidiaries with their officers, directors and, through the President or the Chief Financial Officer of the Company, its key
employees and accountants, and (iv) review such information as is reasonably requested all at such reasonable times and as often as may be reasonably requested. The Purchaser agrees to use commercially reasonable efforts to exercise such rights
in a manner so as not to disrupt unreasonably the Company’s ordinary course of business activities and to maintain, and to use its commercially reasonable efforts to cause its representatives to maintain, the confidentiality of any information
so obtained by it. Notwithstanding anything to the contrary contained in this Agreement, the Company agrees that Purchaser shall have no obligation to demonstrate that the purpose of such inspection, examination, discussion or review is proper or
reasonably related to its investment under any applicable Law. 
 5.2 Maintenance of Properties; Books and Records. The
Company and each of its Subsidiaries shall keep their properties in good repair, working order and condition, and from time to time will make all necessary and appropriate repairs, replacements, additions and improvements thereto, so that the
business carried on by them will be conducted at all times in accordance with prudent business management. The Company and each of its Subsidiaries shall make and keep books, records and accounts, which, in reasonable detail, accurately and fairly
reflect its transactions, and shall devise and maintain a system of internal accounting controls sufficient to provide reasonable assurances that: (a) transactions are executed in accordance with management’s general or specific
authorization; (b) transactions are recorded as necessary to permit preparation of the financial statements required herein and to maintain accountability for assets; and (c) access to assets is permitted only in accordance with
management’s general or specific instructions and recorded assets are compared with existing assets at reasonable intervals and appropriate action is taken with respect to any difference. 

  
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 5.3 Other Insurance. The Company and each of its Subsidiaries shall maintain
insurance against such risks and in at least such amounts as is customarily carried by companies of established reputations engaged in the same or a similar business, under valid and enforceable policies issued by insurers of recognized
responsibility. 
 5.4 Contracts and Agreements. The Company and each of its Subsidiaries shall comply in all material
respects with the provisions of all contracts, indentures, instruments and agreements to which it is a party or by which its properties are bound, and with all other obligations which it incurs or to which it becomes subject. 

5.5 Taxes. The Company and each of its subsidiaries shall pay and discharge when payable all federal, state, local, and foreign
taxes, assessments, penalties, interest and governmental charges which become payable by it or which shall be imposed upon its properties, and all claims for labor, materials or supplies which if unpaid might by law become a lien upon any of its
properties; provided, however, that the Company and its Subsidiaries may in good faith contest any tax, assessment, penalty, or charge, provided that such contest is asserted in accordance with applicable procedures. 

5.6 Compliance with Laws. The Company and each of its Subsidiaries shall comply with all Laws, rules and regulations of all
governmental authorities and agencies applicable to them, their business or their properties. 
 5.7 D&O Insurance.
The Company and each of its Subsidiaries shall maintain directors’ and officers’ insurance in form and substance reasonably satisfactory to the Purchaser, but in no event shall such insurance provide for coverage of less than US$5,000,000.

 5.8 Appointment of Director. Immediately after the Closing, the authorized size of the Board of Directors of the
Company shall be increased to eight (8) directors, and the members of the Board of Directors of the Company shall be (and will consist solely of) initially the following individuals: Mr. Kurt Briner, Mr. Heinz Haller,
Mr. Jean-François Huc, Mr. Taro Inaba, Mr. Denis Lucquin, Mr. William Camp, Mr. Jorge Nogueira and Mr. Raymond J. Land. Immediately after the Closing, the Company shall enter into an indemnification
agreement with Mr. Nogueira in the form executed by the Company and non-management members of the Board of Directors. 

5.9 Satisfaction of Closing Conditions. The Company shall use its reasonable best efforts to satisfy all of the closing conditions
set forth in Section 6. 
 5.10 Use of Proceeds. The Company will use the proceeds of the sale of the
Securities for general operating purposes and potential asset acquisitions as approved by the Board of Directors and subject to any approval rights granted to some or all of the shareholders pursuant to the terms of the Shareholders Agreement.

 6. Conditions to Obligation of the Purchaser to Close. The obligations of the Purchaser to purchase the Securities at the Closing are
subject to the fulfillment, on or before the Closing, of each of the following conditions unless waived in writing: 
 6.1
Representations and Warranties. Each of the representations and warranties of the Company set forth in this Agreement shall be true and correct in all material respects as of the Execution Date and as of the Closing Date (except that where a
representation or warranty is by its terms qualified by materiality, the representation or warranty, as so qualified, shall be true and correct in all respects). 

  
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 6.2 Performance. The Company shall have performed and complied in all material
respects with all agreements, covenants, obligations and conditions required by this Agreement to be performed or complied with by the Company on or prior to the Closing Date. 
 6.3 Absence of Material Adverse Effect. 
 (a) Since the
Execution Date, no event, change, effect or development shall have occurred that, individually or in the aggregate, has had or would reasonably be expected to have, a Material Adverse Effect (as defined below). 

(b) For purposes of this Agreement, the term “Material Adverse Effect” means a material adverse effect on
(a) the business, financial condition, operations, assets, or prospects of the Company or its Subsidiaries, or (b) the ability of the Company to perform its obligations under this Agreement and the Closing Documents and to consummate the
transactions contemplated hereby and thereby. 
 6.4 Closing Deliveries. The Company shall have each of the items and
deliveries required to be delivered at the Closing pursuant to Section 2.1 hereof. 
 6.5 Certificate. The
Key Company Personnel, in their capacity as officers, shareholders and/or directors of the Company, shall deliver to the Purchaser a certificate certifying that each of the conditions set forth in Sections 6.1, 6.2 and 6.3 has
been satisfied. The delivery of such certificate to the Purchaser shall be deemed to constitute the satisfaction of such conditions. 
 6.6 Purchaser Deliveries. The Purchaser shall have (a) executed and delivered a copy of this Agreement, including Exhibits A, B, C and D hereof, and any other agreements required to be
delivered hereunder and (b) delivered the Purchase Price. 
 6.7 Termination by the Purchaser for
Failure of Closing Conditions. This Agreement may be terminated by the Purchaser in the event that all of the conditions set forth in this Section 6 (other than this Section 6.7) do not occur on or before
February 8th, 2012 and, upon such termination by the
Purchaser, this Agreement shall become null and void, and there shall be no liability or obligation on the part of the Purchaser or its respective officers, directors, stockholders or affiliates. 

6.8 Preemptive Rights. The Company shall have fully satisfied (including with respect to rights of timely notification) or
obtained enforceable waivers in respect of any preemptive rights directly or indirectly affecting any of its securities and provided Purchaser evidence of such waivers or satisfaction. 

  
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 6.9 Opinion of Company Counsel. The Purchasers shall have received legal opinions
from each of (i) Boivin Desbiens Senécal Chalifour, (ii) Carter Ledyard & Milburn, and (iii) Morris Nichols Arsht & Tunnell LLP, dated as of the Closing, in substantially the form of Exhibit E attached
hereto. 
 7. Miscellaneous. 
 7.1 Governing Law. All questions concerning the construction, validity and interpretation of this Agreement and the exhibits and schedules hereto shall be governed by and construed in accordance
with the internal Laws of the State of Delaware, without giving effect to any choice of Law or conflict of law provision or rule (whether of the State of Delaware or any other jurisdiction) that would cause the application of the Laws of any
jurisdiction other than the State of Delaware. 
 7.2 Dispute Resolution. 

(a) With respect to any claims, counterclaims, demands, causes of action, disputes, controversies, and other matters in question arising
out of or relating to this Agreement including any questions regarding its existence, validity or termination, any provision hereof, the alleged breach thereof, or in any way relating to the subject matter of this Agreement or the relationship
between the parties hereto created by this Agreement, (referred to herein as a “Dispute”), any party hereto may initiate the dispute resolution procedures set forth in Sections 7.2(b) though 7.2(e) hereof. Except as
provided in Section 7.2(e), such procedures shall be the sole and exclusive procedures for the resolution of any such Dispute. 
 (b) Initiation of Procedures. Any party wishing to initiate the dispute resolution procedures set forth herein with respect to a Dispute not resolved in the ordinary course of business, shall give
written notice of the Dispute to the other parties and of its initiation of the negotiation procedure set forth in Section 7.2(c) below (the “Dispute Notice”). The notice shall include (a) a statement of that
party’s position and a summary of arguments supporting that position, and (b) the name and title of the executive who will represent that party, and of any other person who will accompany the executive, in the negotiations under
Section 7.2(c) below. 
 (c) Negotiation Between Executives. If one party has given a Dispute Notice
pursuant to Section 7.2(b) above, the parties shall promptly attempt in good faith to resolve the Dispute by negotiations between executives who have authority to settle the controversy and who are at a higher level of management
than those directly involved in the Dispute. 
 (d) Arbitration. If the Dispute has not been resolved by negotiation
under Section 7.2(b) within thirty (30) days of the Dispute Notice (or such longer period agreed to by the executives), and only in such event, any party may initiate the arbitration procedure of this
Section 7.2(d) with respect to such Dispute and only with respect to such Dispute by giving written notice thereof to the other parties (the “Arbitration Notice”). Such Dispute shall be finally determined and
resolved by binding arbitration in accordance with the procedures in this document and the Commercial Arbitration Rules of the American Arbitration Association (“AAA Rules”) as in effect on the date such Dispute arises. In the event
of a conflict, the provisions of this document will control. 

  
 22 

 (i) Any arbitration will be conducted at the Pittsburgh, Pennsylvania office of the AAA.
The arbitration will be conducted before a panel of three arbitrators, regardless of the size of the Dispute, to be selected as provided in the AAA Rules; provided, however, that no more than one of the three arbitrators shall be a full-time
accounting professional. Any issue concerning the extent to which any Dispute is subject to arbitration, or concerning the applicability, interpretation or enforceability of these procedures, including any contention that all or part of these
procedures are invalid or unenforceable, shall be governed by the Federal Arbitration Act and resolved by the arbitrators. No potential arbitrator may serve on the panel unless he or she has agreed in writing to abide and be bound by these
procedures. 
 (ii) The arbitrators may not award non-monetary or injunctive relief of any sort. The arbitrators shall have no
power to award punitive damages or any other indirect damages, and the parties expressly waive their right to obtain such damages in arbitration or in any other forum. In no event, even if any other portion of these provisions is held to be invalid
or unenforceable, shall the arbitrators have power to make an award or impose a remedy that could not be made or imposed by a federal court deciding the matter in the same jurisdiction. The arbitrator shall determine the allocation of the costs and
expenses of the arbitration, including the arbitrator’s fee and the parties’ attorneys’ fees and expenses, based upon the extent to which each party prevailed in the arbitration. 

(iii) No discovery will be permitted in connection with the arbitration unless expressly authorized by the arbitration panel upon a
showing of substantial need by the party seeking discovery. 
 (iv) All aspects of the arbitration shall be treated as
confidential. Neither the parties nor the arbitrators may disclose the existence, content or results of the arbitration, except as necessary to comply with legal or regulatory requirements. Before making any such disclosure, a party shall give
written notice to all other parties and shall afford such parties a reasonable opportunity to protect their interests. 
 (v)
The arbitrators shall render a written decision stating specifically the reasons of the fact and law on which the decision is based. 
 (vi) The result of the arbitration will be binding on the parties, and judgment on the arbitrators’ award may be entered in any court having jurisdiction. Any party may contest the Arbitrators’
decision and seek to have the award vacated, modified or corrected in a court of competent jurisdiction based only on the grounds that: (i) the decision is not in conformity with The Federal Arbitration Act (9 USC Sections 10-11); or
(ii) where the arbitrators’ findings of fact are not supported by substantial evidence; or (iii) the decision was based on an erroneous conclusion of law. 
 (e) Injunctive Relief. Notwithstanding anything to the contrary in this Agreement including the foregoing Dispute Resolution provisions, any party may seek injunctive relief, including specific
performance, in a court of law or equity for matters arising out of or 

  
 23 

 
relating to this Agreement. For purposes of this Section only, the parties stipulate and agree to the sole and exclusive jurisdiction of the United States District Court for the Western District
of Pennsylvania to consider and hear any request by a party seeking injunctive relief. In the event that the aforementioned United States District Court lacks jurisdiction or venue to hear such a request for injunctive relief, the parties stipulate
and agree to the sole and exclusive jurisdiction of the state courts of the Commonwealth of Pennsylvania, Allegheny County, to consider and hear such a request for injunctive relief. 

7.3 Survival; Indemnification of Purchaser. 

(a) The representations, warranties, certifications, covenants and agreements made in this Agreement or any other Closing
Document shall survive any investigation made by the Purchaser and the closing of the transactions contemplated hereby and thereby. 
 (b) The Company and each of the Key Company Personnel, jointly and severally, hereby agree to hold harmless and indemnify the Purchaser, the Purchaser’s direct and indirect subsidiaries, affiliated
entities and corporations, and each of its partners, officers, directors, employees, stockholders, agents and representatives (referred to as the “Purchaser Indemnitees”) against any and all damages, liabilities, losses (including,
without limitation, losses due to diminution in the value of the Securities), costs and expenses (including attorneys’ fees and expenses), whether or not arising out of third-party claims, based upon, or arising out of, or relating to:
(i) any inaccuracy in, or any breach by the Company of, any representation, warranty, certification or other statement contained in this Agreement or any other Closing Document, or (ii) any breach of any covenant or agreement contained in
this Agreement or any other Closing Document, or (iii), any tax imposed on the Company (A) with respect to a taxable period or portion thereof ending on or before the Closing Date, (B) as a transferee or successor, by contract or pursuant
to any law, to the extent that the liability for such tax relates to transactions or events that occurred on or prior to prior to the Closing, and (C) as a result of the Company being, on or prior to the Closing, a member of an affiliated,
combined, consolidated, unitary or similar group pursuant to section 1.1502-6 of the Treasury Regulations (or any other similar provision of state, local or foreign Law), including but not limited to any taxes associated with the spin-off the
Company by Diversified Natural Products, Inc. (collectively, the “Indemnifiable Claims”). 
 (c)
The Company shall reimburse, promptly following request therefor, all expenses incurred by a Purchaser Indemnitee in connection with any Indemnifiable Claim, including, without limitation, any threatened, pending or completed action, suit,
arbitration, investigation or other proceeding arising out of, or relating to, any Indemnifiable Claim. 
 (d)
The rights to indemnification set forth in this Section 7.3 are in addition to, and not in limitation of, all rights and remedies to which the Purchaser may have in equity, including the right to seek specific performance, rescission or
restitution, none of which such rights or remedies shall be affected or diminished by this Section 7.3. All remedies, either under this Agreement or any other Closing Document, the Company’s Organizational Documents or otherwise
afforded to any party, shall be cumulative and not alternative. 

  
 24 

 (e) Notwithstanding anything else contained herein, it is understood and
agreed that the liability of any Key Company Personnel to the Purchaser Indemnitees pursuant to this Section 7.3 shall be limited to any shares of Common Stock of the Company currently owned by such Key Company Personnel (including any
stock options and warrants which may be converted or exchanged into shares of Common Stock of the Company), together with any cash proceeds which result from the sale or exercise thereof, and such Key Company Personnel shall discharge such liability
by the surrender of such securities and/or any proceeds which have been received from the sale or exercise thereof. 
 7.4
Consent to Amendments and Waivers. Except as otherwise expressly provided herein, the provisions of this Agreement may be amended and the Company may take any action herein prohibited, or omit to perform any act herein required to be
performed by it, only if the Company has obtained the prior written consent of the Purchaser. No other course of dealing between the Company and the Purchaser or any delay in exercising any rights hereunder or under the Amended and Restated
Certificate of Incorporation of the Company shall operate as a waiver of any rights of any Purchaser. Any amendment or waiver effected in accordance with this Section 7.4 shall be binding upon the Company and the Purchaser, and their
respective successors and assigns. 
 7.5 Entire Agreement. This Agreement and the Closing Documents constitute the
entire agreement among the parties relative to the specific subject matter hereof and thereof. 
 7.6 Notices. All
notices and other communications provided for herein shall be dated and in writing and shall be deemed to have been duly given (i) on the date of delivery, if delivered by facsimile, receipt confirmed, (ii) on the following business day,
if delivered by a reputable nationwide overnight courier service guaranteeing next business day delivery; provided that, notices and other communications sent from or delivered outside of the United States of America shall be sent by a reputable
international express courier service and shall be deemed to have been duly given upon delivery to the recipient, and (iii) two business days after being sent by certified or registered mail, return receipt requested, postage prepaid; provided
that, notices and other communications sent from or delivered outside of the United States of America by certified or registered mail, return receipt requested, postage prepaid shall be deemed to have been duly given upon delivery to the recipient,
in each case, to the party to whom it is directed at the following address (or at such other address as any party hereto shall hereafter specify by notice in writing to the other parties hereto): 

If to the Company, to the following address: 
 BioAmber Inc. 
 1250, Rene-Levesque Boulevard West, Suite 4110 

Montreal, Quebec, Canada 
 H3B 4W8 
 Attention: Mr. Jean-François Huc, President & CEO

 Facsimile: *** 

  
 25 

 with a copy (which shall not constitute notice) to: 

Boivin Desbiens Senécal, g.p. 
 *** 
 If to the Purchaser: 

Lanxess Corporation 
 111 RIDC Park West Drive 
 Pittsburgh 

Pennsylvania 15275-1112 
 Attention: Marcy Tenaglia, Vice President, General Counsel and Secretary 

Facsimile: *** 

7.7 Severability. In the event one or more of the provisions of this Agreement should, for any reason, be held to be invalid,
illegal or unenforceable in any respect, such invalidity, illegality, or unenforceability shall not affect any other provisions of this Agreement, and this Agreement shall be construed as if such invalid, illegal or unenforceable provision had never
been contained herein. 
 7.8 Counterparts; Delivery by Facsimile of PDF. This Agreement may be executed in two or more
counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. This Agreement, the agreements referred to herein, and each other agreement or instrument entered into in connection
herewith or therewith or contemplated hereby or thereby, and any amendments hereto or thereto, to the extent signed and delivered by means of a facsimile machine or by other electronic transmission of a manual signature (by pdf or other method that
enables the recipient to reproduce a copy of the manual signature), shall be treated in all manner and respects as an original agreement or instrument and shall be considered to have the same binding legal effect as if it were the original signed
version thereof delivered in person. At the request of any party hereto or to any such agreement or instrument, each other party hereto or thereto shall re-execute original forms thereof and deliver them to all other parties. No party hereto or to
any such agreement or instrument shall raise the use of a facsimile machine or electronic transmission in pdf format to deliver a signature or the fact that any signature or agreement or instrument was transmitted or communicated through the use of
a facsimile machine or electronic transmission in pdf as a defense to the formation or enforceability of a contract and each such party forever waives any such defense. 

  
 26 

 7.9 Successors and Assigns. Neither the Company nor the Purchaser may assign its
rights and obligations under this Agreement except upon written consent of the Purchaser (with respect to an assignment by the Company) or the Company (with respect to an assignment by the Purchaser, as applicable); provided that, the
provisions of this Agreement that are for the Purchaser’s benefit as a purchaser or holder of Securities are also for the benefit of, and enforceable by, any subsequent holder of such Securities but only if a transfer to such holder of the
Securities complies with all applicable provisions of the Shareholders Agreement. Subject to the immediately foregoing sentence, all covenants and agreements contained in this Agreement by or on behalf of any of the parties hereto shall bind and
inure to the benefit of the respective successors and permitted assigns of the parties hereto whether so expressed or not. Notwithstanding the foregoing, this Agreement cannot be assigned to a new investor without the consent of the Company, unless
such new investor is an affiliate of a Purchaser. 
 7.10 Titles and Subtitles. The titles of the sections and
subsections of this Agreement are for convenience of reference only and are not to be considered in construing this Agreement 

7.11 No Brokers. The Purchaser represents and warrants that no agent, broker, investment banker, person or firm acting on behalf
of or under the authority of the Purchaser is or will be entitled to any broker’s or finder’s fee or any other commission directly or indirectly in connection with the transactions contemplated herein. The Purchaser agrees to indemnify the
Company against any fee or commission payable by the Company for which such Purchaser is responsible. 
 7.12 Expenses.
The Company and the Purchaser shall each bear their respective costs, expenses and fees, (including legal and other advisor fees) incurred in connection with the negotiation of this Agreement and the documents contemplated hereunder, and the
consummation of the transactions contemplated hereunder. 
 7.13 Public Disclosure. The parties to this Agreement agree
that it is their intent to publicly disclose the conclusion of the transaction provided in this Agreement, subject to the Company and the Purchaser agreeing in writing beforehand on the content of any press release and the timing of its release.
Until the disclosure of such press release, the parties agree that the transactions provided in this Agreement shall remain confidential and no public disclosure thereof shall be made by any party to this Agreement. 

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK] 

  
 27 

 IN WITNESS WHEREOF, the parties hereto have duly executed this Stock Purchase Agreement as
of the date set forth in the first paragraph hereof. 
  

			
	BIOAMBER INC.
		
	By:	 	 /s/ Jean-François Huc

	Name:	 	Jean-François Huc
	Title:	 	President & CEO
	
	LANXESS CORPORATION
		
	By:	 	 /s/ Randall S. Dearth

	Name:	 	Randall S. Dearth
	Title:	 	President & CEO

 EXHIBIT C 
 Undertaking 
 WHEREAS, in connection with a private placement for
gross proceeds of US$9,999,910, BioAmber Inc. (the “Corporation”) is issuing an aggregate of 10,030 shares of common stock of the Corporation to Lanxess Corporation (“Lanxess”) pursuant to a Stock Purchase
Agreement entered into between the Corporation and Lanxess on the date hereof and, the latter will become a shareholder of the Corporation; 
 WHEREAS, according to the terms of the Amended and Restated Shareholders’ Agreement of the Corporation dated April 15, 2011, as amended on November 4, 2011 and February 6,
2012 (the “Shareholders’ Agreement”), namely the provisions provided at its section 1.1, a Shareholder (as defined in the Shareholders’ Agreement”) shall include a Security Holder (as defined in the
Shareholders’ Agreement”) who becomes a holder of Shares (as defined in the Shareholders’ Agreement”) subsequent to the date of the Shareholders’ Agreement; 

WHEREAS, according to the terms of section 2.3., the Corporation hereby covenants to require any purchaser of Shares or
Convertible Securities becoming a holder of such security after the date of the Shareholders’ Agreement to become a party to such Agreement and to meet the requirements set forth in the Shareholders’ Agreement, including but not
limited to Section 6.2.1., 6.2.2., 6.2.3. and 6.2.4. 

THEREFORE, LANXESS HERETO AGREES AS FOLLOWS: 
  

	1.	Lanxess hereby declares that it has read the Shareholders’ Agreement, understands its meaning and scope and is satisfied therewith.

  

	2.	Lanxess hereby agrees (i) to become a party to the Shareholders’ Agreement, as a Shareholder and as an Investor (as these terms are defined in the
Shareholders’ Agreement), and (ii) that it declares itself bound by each of the provisions of the Shareholders’ Agreement applicable to it, as a Shareholder and as an Investor (as these terms are defined in the
Shareholders’ Agreement), which provisions it undertakes to respect as a party to the Shareholders’ Agreement. 

  

	3.	Lanxess hereby confirms that any notice to be sent to it in connection with this Undertaking and the Shareholders’ Agreement shall be sent in accordance with
Section 12.2 of the Shareholders’ Agreement to it at the following address: 

 Lanxess Corporation

 111 RIDC Park West Drive 
 Pittsburgh 
 Pennsylvania 15275-1112 

Attention: Marcy Tenaglia, Vice President, General Counsel and Secretary 

Facsimile: *** 
  

	4.	Delivery of an executed counterpart of this Undertaking may be made by means of a facsimile machine or as an attachment in “pdf” or similar format to an
electronic mail message. 

 Signed as of February 6, 2012. 

 

			
	LANXESS CORPORATION
		
	By:	 	  

			
	Name:	 	

 
			
	Title:Lease Agreement

 Exhibit 10.46 
 TABLE OF CONTENTS 
  

							
	 	 	 	  	PAGE	 
			
	1.	 	Premises and Term	  	 	1	  
			
	2.	 	Base Rent, Late Payment Charges and Security Deposit	  	 	1	  
			
	3.	 	Use	  	 	2	  
			
	4.	 	Operating Costs; Additional Rent	  	 	2	  
			
	5.	 	Landlord’s Responsibilities	  	 	3	  
			
	6.	 	Tenant’s Responsibilities	  	 	4	  
			
	7.	 	Alterations; Condition of Premises Upon Expiration	  	 	5	  
			
	8.	 	Signs/Window Coverings	  	 	5	  
			
	9.	 	Inspection	  	 	5	  
			
	10.	 	Utilities	  	 	5	  
			
	11.	 	Assignment and Subletting	  	 	6	  
			
	12.	 	Fire and Casualty Damage	  	 	6	  
			
	13.	 	Reciprocal Indemnification; Waiver and Release	  	 	7	  
			
	14.	 	Insurance	  	 	8	  
			
	15.	 	Condemnation	  	 	9	  
			
	16.	 	Holding Over	  	 	9	  
			
	17.	 	Quiet Enjoyment	  	 	10	  
			
	18.	 	Events of Default	  	 	10	  
			
	19.	 	Remedies	  	 	10	  
			
	20.	 	Intentionally Left Blank	  	 	12	  
			
	21.	 	Mortgages	  	 	12	  
			
	22.	 	Mechanic’s Liens	  	 	12	  
			
	23.	 	Notices	  	 	12	  
			
	24.	 	Hazardous Substances	  	 	12	  
			
	25.	 	Expense of Enforcement	  	 	13	  
			
	26.	 	Intentionally Left Blank	  	 	13	  
			
	27.	 	Transfer of Landlord’s Interest; Limitation of Liability	  	 	13	  
			
	28.	 	Right of Landlord to Perform	  	 	13	  
			
	29.	 	Miscellaneous	  	 	14	  
			
	30.	 	Exhibits	  	 	15	  
			
	31.	 	Removal of Existing Improvements	  	 	15	  
		
	 Exhibit A – Depiction of Premises
  

Exhibit B – Rules and Regulations
  

Exhibit C – Intentionally Omitted
  

Exhibit D – Signage Criteria
  

Exhibit E – Move-Out Standards
  

Exhibit F – Existing Improvements
	  			

 DATA SHEET 

 

							
	DATE OF LEASE:	  	December 20, 2011
		
	LANDLORD:	  	ST. PAUL FIRE AND MARINE INSURANCE COMPANY, a Connecticut corporation
		
	LANDLORD’S ADDRESS FOR RENT:	  	 St. Paul Fire and Marine Insurance Company
 c/o NorthMarq Real Estate Services, LLC
 SDS-12-2659, PO Box 86

Minneapolis, MN 55486-2659

		
	TENANT:	  	BioAmber Inc., a Delaware corporation
		
	TENANT’S ADDRESS:	  	Suite 180, 3850 Annapolis Lane, Plymouth, Minnesota, 55447
		
	PREMISES:	  	Approximately 27,259 rentable square feet, as designated on Exhibit A.
		
	COMMENCEMENT DATE:	  	March 1, 2012.
		
	EXPIRATION DATE:	  	February 29, 2016.
		
	TERM:	  	48 months, beginning on the Commencement Date, and ending on the Expiration Date, unless earlier terminated as provided in this Lease.
		
	BASE RENT:	  	Base Rent shall be due hereunder as follows:

 

									
	 Period
	  	Monthly Base Rent	 	  	Annual Base Rent	 
	March 1, 2012 – February 28, 2013	  	$	13,038.89	  	  	$	156,466.68	  
	March 1, 2013 – February 28, 2014	  	$	13,356.91	  	  	$	160,282.92	  
	March 1, 2014 – February 28, 2015	  	$	13,697.65	  	  	$	164,371.80	  
	March 1, 2015 – February 29, 2016	  	$	14,038.39	  	  	$	168,460.68	  

  

					
	USE:	  	Office/laboratory/warehouse	  	
			
	ADDRESSES FOR NOTICES:	  	Landlord:	  	with a copy to Landlord’s Managing Agent:
			
		  	 St. Paul Fire and Marine Insurance Company
 385 Washington Street
 St. Paul, Minnesota 55102

Attn: Vice President, Asset Management
	  	 NorthMarq Real Estate Services, LLC
 3500 American Blvd. West, Suite 200
 Bloomington, Minnesota 55431

Attn: Vice President, Property Management

			
		  	Tenant: at the Premises, with a copy to:	  	
			
		  	 Boivin Desbiens Senécal s.e.n.c.
 ***
	  	
			
	SECURITY DEPOSIT:	  	$20,695	  	
		
	PHASE:	  	Phase I, Plymouth Business Center, consisting of two buildings with a combined rentable area of 104,005 rentable square feet.
			
	TENANT’S PROPORTIONATE SHARE:	  	26.21% of Phase I, Plymouth Business Center.	  	

			
	BUILDING:	  	3850 Annapolis Lane, the building in which the Premises are located, which building is a part of Phase I, Plymouth Business Center.
		
	LANDLORD’S WORK:	  	Landlord agrees to create a vestibule install new carpet and paint in the office portion of the Premises that is crosshatched on the attached Exhibit A within 90 days after the
Commencement Date subject to Tenant-caused delays and force majeure. Tenant shall coordinate with Landlord and Landlord’s contractor to schedule the performance of the Landlord’s Work during normal business hours.
		
	TENANT’S BROKER:	  	None
		
	LANDLORD’S BROKER:	  	Northmarq Brokerage Services, LLC (Dave Paradise)
	
	The information in this Data Sheet is incorporated in and made a part of this lease agreement.

 LEASE AGREEMENT 

THIS LEASE AGREEMENT (“Lease”) is between Landlord and Tenant as of the Date of Lease. 

W I T N E S E T H: 
 1. Premises and Term. 
 (a) In consideration of the
obligation of Tenant to pay Rent (as defined in Paragraph 4(g)), and in consideration of the other terms, provisions and covenants hereof, Landlord hereby leases to Tenant, and Tenant hereby takes from Landlord the Premises designated on the Data
Sheet, as shown on the plan attached hereto as Exhibit A, which Premises are located in the Building, together with all rights, privileges, easements, appurtenances, and immunities belonging to or in any way pertaining to the Premises, TO
HAVE AND TO HOLD the same for the Term. 
 (b) Tenant is in possession of the Premises on the date of this Lease
under a sublease (the “Sublease”) between DNP Green Technology, Inc., a Delaware corporation (“DNP”) and the current tenant of the Premises, GenMab MN, Inc. (“GenMab”). On November 16, 2010, by an amendment to its
articles of incorporation filed with the Secretary of State of Delaware, DNP changed its name to BioAmber Inc. The term of the lease under which Tenant is subleasing the Premises on the date of this Lease is scheduled to expire on February 29,
2012. Therefore, Tenant hereby accepts possession of the Premises on the Commencement Date under this Lease in their “as-is” condition on the Commencement Date. Landlord has no obligation to perform any work in or about the Premises or
anywhere else as a condition to Tenant’s acceptance of possession of the Premises under this Lease or the commencement of the Term of this Lease, other than the Landlord’s Work, which Landlord shall perform after the Commencement Date in
accordance with the Data Sheet. 
 2. Base Rent, Late Payment Charges and Security Deposit. 

(a) Base Rent. Tenant agrees to pay to Landlord Base Rent for the Premises, in advance, without demand, deduction
or set off, for the entire Term at the rate stated in the Data Sheet, except that the monthly installment for the first month of the Term is due and payable on the date of this Lease. Thereafter, one such monthly installment is be due and payable,
in advance, without demand, deduction or set off on or before the first day of each calendar month succeeding the Commencement Date during the Term. It is understood and agreed that Tenant’s obligation to pay Base Rent, Operating Costs (as
defined in Paragraph 4(a) hereof) and any Additional Rent under this Lease shall constitute an independent covenant. 
 (b) Late Charge; Interest. If Tenant fails to pay any installment of Rent, including any amount treated as Additional Rent (as defined in Paragraph 4(g)) of this Lease, or other sums hereunder
prior to the date such installment or other charge becomes delinquent pursuant to Paragraph 18, Tenant shall pay to Landlord on demand a late charge of $500.00 for each late installment or other charge to help defray the additional cost to Landlord
for processing such late payments, and such late charge shall be Additional Rent. In addition to the foregoing, to the extent Rent is not paid on or before the date the same becomes delinquent pursuant to Paragraph 18, all unpaid Rent shall accrue
interest from the first day of each month at a rate that is the lesser of (i) eighteen percent (18%) per annum; or (ii) the highest amount permitted by applicable law and such interest shall constitute Additional Rent and shall be
payable with the next installment of Base Rent falling due. The provision for the payment of such late charge and interest shall be in addition to all of Landlord’s other rights and remedies hereunder or at law and shall not be construed as
liquidated damages or as limiting Landlord’s remedies in any manner. 
 (c) Security Deposit. Tenant
agrees to deposit with Landlord on the date hereof the Security Deposit as stated on the Data Sheet, which Security Deposit shall be held by Landlord, without interest, as security for the performance of Tenant’s covenants and obligations under
this Lease, it being expressly understood and agreed that such deposit is not an advance rental deposit or a measure of Landlord’s damages in case of Tenant’s default. Upon the occurrence of any Event of Default (as defined in Paragraph 18
below) by Tenant, Landlord may, from time to time, without prejudice to any other remedy provided herein or provided by law, apply such Security Deposit to any arrears of Rent or other payments due Landlord under this Lease, and any other damage,
injury, expense or liability caused by such Event of Default without waiving such Event of Default, and Tenant shall pay to Landlord on demand the amount so applied in order to restore the Security Deposit to its original amount, which amount shall
constitute Additional Rent. Although the Security Deposit shall be deemed the property of Landlord, subject to the provisions of Paragraph 27(a) hereof, Landlord agrees to refund to Tenant the remaining balance of such Security Deposit, if any,
within thirty (30) days after the date following the Expiration Date that Landlord determines that all of Tenant’s obligations under this Lease have been fulfilled. 

  
 1 

 3. Use. The Premises shall be used only for the Use stated on the Data Sheet and for
such other lawful purposes as may be incidental thereto. Outside storage, including without limitation, trucks and other vehicles, garbage containers and outdoor furniture are prohibited without Landlord’s prior written consent. Tenant shall,
at its own cost and expense, obtain any and all licenses and permits necessary for Tenant’s Use prior to the Commencement Date. Further, Tenant shall be responsible for ensuring that the Use is an allowable use under the zoning code of the City
of Plymouth, as the same may be amended from time to time, it being understood and agreed that the fact that the Use is not allowed shall not excuse Tenant’s full payment and performance under this Lease. Landlord makes no representations or
warranties of any kind or nature that the Use is a permitted use under the zoning code of the City of Plymouth or any other governmental entity or agency with jurisdiction over the Building. 

Tenant shall comply with all governmental laws, ordinances and regulations applicable to the Use of the Premises, and shall promptly
comply with all governmental orders and directives for the correction, prevention and abatement of nuisance in or upon, or connected with, the Premises, all at Tenant’s sole expense. Tenant shall not receive, store or otherwise handle on the
Premises any product, material or merchandise that is explosive or highly flammable. Tenant will not permit the Premises to be used for any purpose or in any manner (including without limitation any method of storage) that would render the insurance
on the Building or the property on which the Phase is located (“Property”) void or the insurance risk more hazardous or cause the State Board of Insurance or other insurance authority to disallow any sprinkler credits. If any increase in
the fire and extended coverage insurance premiums paid by Landlord for the Building is caused by Tenant’s use and occupancy of the Premises, then Tenant shall pay to Landlord the amount of such increase, within ten (10) days after written
demand therefor, as Additional Rent. 
 4. Operating Costs; Additional Rent. 

(a) Operating Costs. Subject to the provisions of Paragraph 2(a) hereof, beginning on the Commencement Date and on
the first day of each month thereafter during the Term, Tenant shall pay to Landlord, without demand, deduction or setoff, Tenant’s proportionate share of Operating Costs, as defined below, calculated on the basis of Tenant’s Proportionate
Share stated on the Data Sheet. 
 As used in this Lease, the term “Operating Costs” shall mean any and
all expenses, costs and disbursements of any kind and nature whatsoever incurred by Landlord in connection with the ownership, management, maintenance, operation and repair of the Property, the Phase or the Building that Landlord shall pay or become
obligated to pay in respect of a calendar year (regardless of when such Operating Costs were incurred). Operating Costs shall include, without limitation, the costs of maintenance, repairs, and, subject to the provisions of Paragraph 5 hereof,
replacements to the Building, including, without limitation, downspouts, gutters, painting, sprinkler systems, roof and walls; the costs of maintaining and repairing parking lots, parking structures and easements; property management fees, salaries,
fringe benefits and related costs payable to employees of Landlord’s Managing Agent whose duties are connected with the Property; insurance costs, all heating and air conditioning costs not payable by Tenant pursuant to Paragraph 6 hereof,
electricity, sewer and water and other utility costs not separately metered to tenants, including Tenant, landscape maintenance, trash and snow removal, Taxes, as defined in Paragraph 4(e), and costs and expenses incurred by Landlord in protesting
any assessments, levies or the tax rate. Operating Costs shall not include the following: (i) costs of alterations of any tenant’s premises, including the Premises; (ii) costs of curing construction defects to the base Building;
(iii) depreciation; (iv) interest and principal payments on mortgages, and other debt costs; (v) real estate brokers’ leasing commissions or compensation; (vi) any cost or expenditure (or portion thereof) for which Landlord
is reimbursed, whether by insurance proceeds or otherwise; (vii) cost of any service furnished to any other occupant of the Building that Landlord does not provide to Tenant hereunder; (viii) the full replacement of (A) roofs,
(B) exterior walls (as defined in Paragraph 5) and (C) foundations; (ix) attorney’s fees, costs and disbursements and other expenses incurred in connection with negotiations or disputes with tenants, other occupants, or
prospective tenants or other occupants; (x) costs incurred due to violation by Landlord or any other tenant of the terms and conditions of this Lease; (xi) overhead and profit increment paid to subsidiaries or affiliates of Landlord for
services on or the real property, to the extent only that the costs of such services exceed competitive costs of such services were they not so rendered by a subsidiary or affiliate; (xii) rent under any ground or underlying leases or lease; or
rent or lease payments for parking; (xiii) Landlord’s general corporate overhead and general administrative expenses; (xiv) any compensation paid to clerks, attendants or other persons in commercial concessions operated by Landlord;
(xv) all costs for which Tenant reimburses Landlord or pays third persons; and (xvi) advertising and promotional expenditures. Notwithstanding anything to the contrary in this Lease, Operating Costs shall not include the full amount of any
Capital Cost in the year incurred, but Operating Costs shall include amortization of each Capital Cost over the useful life of the relevant repair or replacement, as determined by Landlord in its reasonable discretion, together with interest at the
rate of 9% per year. For the purposes of the preceding sentence, the term “Capital Cost” means the cost of any repair or replacement that is considered a capital repair or replacement under generally accepted accounting principles in
use in the real estate industry on the date of the relevant repair or replacement, except that any particular repair or replacement that costs less than $20,000 is not a Capital Cost. 

(b) Estimated Operating Costs. Promptly after the commencement of this Lease and during January of each year or as
soon thereafter as practicable, Landlord shall give Tenant written notice of its estimate of amounts payable under Paragraph 4(a) for such calendar year. On or before the first day of each month thereafter, Tenant shall pay to Landlord one/twelfth
(1/12th) of such estimated amounts, provided that if such notice is not given in January, Tenant shall continue to 

  
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pay on the basis of the prior year’s estimate until the first day of the month after the month in which such notice is given, at which time, in addition to paying the first installment of
the estimated amount provided by Landlord for such year, Tenant shall also pay the difference, if any, between the current year’s estimate and the previous year’s estimate for the period from January 1 of such year through the last
day of the month in which the notice was given. If at any time it appears to Landlord that the amounts payable under Paragraph 4(a) for the then current calendar year will vary from its estimate by more than five percent (5%), Landlord may, by
written notice to Tenant, revise its estimate for such year, and subsequent payments by Tenant for such year shall be based upon such revised estimate. 
 Within ninety (90) days after the end of each calendar year or as soon thereafter as practicable, Landlord shall deliver to Tenant a summary of the total Operating Costs for the previous calendar
year and Tenant’s proportionate share thereof, which shall be based upon Tenant’s Proportionate Share as stated in the Data Sheet (the “Summary”). If the Summary shows an amount due from Tenant that is less than the estimated
payments previously paid by Tenant (the “Excess Amount”), Landlord shall credit the Excess Amount against Operating Costs next falling due hereunder until the Excess Amount is exhausted; provided however, that if the summary shows an
Excess Amount for the year in which this Lease expired, and Tenant has fully complied with all of its obligations under this Lease, the Summary shall be accompanied by a refund of the Excess Amount to Tenant. If such Summary shows an amount due from
Tenant that is more than the estimated payments previously paid by Tenant, Tenant shall pay the deficiency to Landlord, as Additional Rent, within thirty (30) days after delivery of the Summary, and Tenant’s failure to do so shall
constitute an Event of Default pursuant to Paragraph 18(a) hereof. The provisions of this subparagraph (b) shall survive the expiration or earlier termination of this Lease. 

(c) Right to Audit. Tenant or its representatives shall have the right to examine Landlord’s books and records
of Operating Costs during normal business hours within twenty (20) days following the furnishing of the Summary to Tenant. Unless Tenant takes written exception to any item within thirty (30) days following the furnishing of the Summary to
Tenant (which item shall be paid in any event), the Summary shall be considered as final and accepted by Tenant. 

(d) Accrual Accounting. If Landlord selects the accrual accounting method rather than the cash accounting method
for operating expense purposes, Operating Costs shall be deemed to have been paid when such expenses have accrued. 
 (e) Taxes. Landlord agrees to pay before they become delinquent all taxes, including, without limitation, real estate taxes, installments of special assessments and governmental charges of any kind
and nature whatsoever, (herein collectively referred to as “Taxes”) lawfully due and payable with respect to the Building, the Phase and the Property. In addition, Tenant shall be liable for all taxes levied or assessed against personal
property, furniture or fixtures placed by Tenant in the Premises. If any such taxes for which Tenant is liable are levied or assessed against Landlord or Landlord’s property and if Landlord elects to pay the same or if the assessed value of
Landlord’s property is increased by inclusion of personal property, furniture or fixtures placed by Tenant in the Premises, and Landlord elects to pay the taxes based on such increase, Tenant shall pay to Landlord that part of such taxes within
ten (10) days after Landlord’s written demand therefor, which amount shall constitute Additional Rent. 

(f) Change in Method of Taxation. If at any time during the Term, the present method of taxation shall be changed
so that in lieu of the whole or any part of any Taxes (including personal property taxes described in Paragraph 4(e) hereof), assessments or governmental charges levied, assessed or imposed on real estate and the improvements thereon, there shall be
levied, assessed or imposed on Landlord a capital levy or other tax directly on the Rent or any portion thereof and/or a franchise tax, assessment, levy or charge measured by or based, in whole or in part, upon such Rent, Landlord’s income or
any portion thereof for the present or any future building or buildings on the Property, then all such taxes, assessments, levies or charges, or the part thereof so measured or based, shall be deemed to be included within the term “Taxes”
for the purposes hereof. 
 (g) Definition of “Rent”. Any amounts in addition to Base Rent and
Operating Costs, chargebacks for work performed by Landlord for the benefit of Tenant, if any, and other costs payable by Tenant to Landlord hereunder, if any, (collectively the “Additional Rent”) shall be an obligation of Tenant hereunder
and all such Additional Rent shall be due and payable upon demand. Base Rent, Operating Costs and Additional Rent may be referred to collectively as “Rent.” 
 5. Landlord’s Responsibilities. Except for reasonable wear and tear and any casualty against which Tenant was obligated to insure under this Lease, and subject to the payment of Operating
Costs as required hereunder, Landlord shall maintain all parts of the Building, other than tenants’ premises, including, without limitation, the Premises, making all necessary repairs and replacements, whether ordinary or extraordinary,
structural or nonstructural, including downspouts, gutters, irrigation sprinkler system; regularly mow any grass, remove weeds and perform general landscape maintenance; and maintain and repair the parking lot and driveway areas. Notwithstanding the
foregoing, Landlord shall be responsible, at its sole cost and expense, for the full (but not partial) replacement of (a) roofs; (b) exterior walls; and (c) foundations and for compliance with Title III of the Americans With

  
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Disabilities Act of 1990, as amended as of the Date of Lease (the “ADA”) solely as to the exterior walls of the Premises, including access to the Building and maintenance of parking.
Tenant shall immediately give Landlord written notice of any defect or need for repairs. Landlord’s liability with respect to any defects, repairs or maintenance for which Landlord is responsible under any of the provisions of this Lease shall
be limited to the cost of such repairs or maintenance or the curing of such defect. The term “exterior walls” as used in this Lease shall not include windows, glass or plate glass, doors, special store fronts or office entries. 

6. Tenant’s Responsibilities. 
 (a) Maintenance of Premises. Tenant shall, at its own cost and expense, keep and maintain all parts of the Premises (except as provided in Paragraph 5) in good condition, promptly making all
necessary repairs and replacements, including but not limited to, windows, glass and plate glass, doors, any special entry, interior walls and finish work, floors and floor covering, heating and air conditioning systems, electrical systems, dock
boards, truck doors, dock bumpers, dock seals, plumbing work and fixtures, termite and pest extermination, regular removal of trash and debris and keeping the parking areas, driveways, alleys and the whole of the Premises in a clean and sanitary
condition. Further, Tenant shall comply with the ADA with respect to the Premises. Tenant shall not be obligated to repair any damage caused by fire, tornado or other casualty covered by the insurance to be maintained by Landlord pursuant to
Paragraph 14(a), except that Tenant shall be obligated to repair all wind damage to glass unless caused by a tornado. 
 (b) Damage to Demising Walls. Tenant shall not damage any demising wall or disturb the integrity and support provided by any demising wall and shall, at its sole cost and expense, promptly repair
any damage or injury to any demising wall caused by Tenant or its employees, agents or invitees. 
 (c)
Parking. Tenant and its employees, customers and licensees shall have the nonexclusive right to use, in common with the other parties occupying the Phase, common parking areas, if any (exclusive of any parking or work load areas designated or
to be designated by Landlord for the exclusive use of Tenant or other tenants occupying or to be occupying other portions of the Phase), driveways and alleys adjacent to the Building, subject to such reasonable rules and regulations as Landlord may
from time to time prescribe. 
 (d) Preventive Maintenance. Tenant shall, at its own cost and expense,
enter into a regularly scheduled preventive maintenance/service contract with a maintenance contractor for servicing all hot water, heating and air conditioning systems and equipment serving the Premises. The maintenance contractor and the contract
must be approved by Landlord. The service contract must include all services suggested by the equipment manufacturer in the operation/maintenance manual and must become effective (and a copy thereof delivered to Landlord) within thirty
(30) days after the date Tenant takes possession of the Premises. 
 (e) Security Measures.

 (i) Tenant acknowledges and agrees that the Building is an industrial building, and, accordingly, the level of
security services, if any, provided by Landlord are only those commonly provided for industrial buildings. Specifically, and without limitation of the foregoing, Landlord does not provide, and the Rent payable hereunder does not include, the cost of
a guard service, an alarm service or other security measures. 
 (ii) Notwithstanding the foregoing, to the
extent Landlord provides any security measures at any time, such security measures are not intended to be and shall not be treated as a guaranty against crime, property damage, personal or bodily injury or death. Landlord does not make, and Tenant
hereby waives any right to make a claim that Landlord has made any guaranty or warranty, express or implied, with respect to security at the Building or the Project or, if any security measures exist, that the same will prevent the occurrence of
and/or the consequences of criminal or other unlawful activity. Without limiting the generality of the foregoing, it is the intent of this Lease that Tenant assume full and complete responsibility for claims, actions, judgments, damages, costs and
expenses, including, without limitation, attorneys’ fees through all appellate levels, arising from or related to bodily injury, personal injury, property damage or death occurring on or about the Premises from any cause whatsoever, including,
without limitation, criminal activity (and including, without limitation, such claims for which Landlord may be, or may be argued to be, liable). 
 (iii) The parties agree that Landlord shall not be liable to Tenant for any injury, damage or loss from any cause whatsoever that is caused (A) in whole or in part arising from any problem, defect,
malfunction or failure of any security measure (if any is provided); or (B) by criminal activity. 
 (iv)
Tenant assumes full responsibility for protecting the Premises from, among other things, theft, robbery, and pilferage. 

  
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 (f) Costs Payable by Tenant. Notwithstanding the provisions of
Paragraph 13(b) below, within ten (10) days after demand by Landlord, Tenant shall pay, as Additional Rent, the cost and expense of repairing any damage to the Premises resulting from and/or caused in whole or in part by the negligence or
misconduct of Tenant, its agents, servants, employees, contractors, patrons, customers, or any other person entering upon the property as a result of Tenant’s business activities or caused by Tenant’s default hereunder. 

7. Alterations; Condition of Premises Upon Expiration. Tenant shall not make any alterations, additions or improvements to the
Premises (including but not limited to roof and wall penetrations) without the prior written consent of Landlord, except that Tenant may make alterations which do not cost, in the aggregate, more than Five Thousand Dollars ($5,000.00) each; provided
such alterations do not affect the Building structure or systems, including, but not limited to, HVAC, plumbing, mechanical and electrical systems, in which case Landlord’s prior written consent must be obtained, which consent shall not be
unreasonably withheld or delayed. Tenant may, without the consent of Landlord, but at its own cost and expense and in a good and workmanlike manner erect such shelves, bins, machinery and trade fixtures as it may deem advisable, without altering the
basic character of the Building and without overloading or damaging such Building, and in each case complying with all applicable governmental laws, ordinances, regulations and other requirements. Prior to commencing any such alterations, additions
or improvements Tenant shall provide such assurances to Landlord, including but not limited to waivers of lien, surety company performance and payment bonds and personal guaranties of persons of substance, as Landlord shall require to assure payment
of the costs thereof and to protect Landlord against any loss from mechanics’, laborer’s, materialmen’s or other liens. All alterations, additions, improvements and partitions erected by Tenant shall be and remain the property of
Tenant during the term of this Lease and Tenant shall, on the Restoration Date (defined below) restore the Premises to the condition described Exhibit E attached hereto and made a part hereof. In addition to the foregoing, all telephone and
data communications cabling (“Cabling”), shall be and remain the property of Tenant during the Term and Tenant shall, unless Landlord otherwise elects as provided below, remove the Cabling by the Restoration Date. For the purposes of this
Lease, “Restoration Date” shall mean the earliest of (a) the Expiration Date, (b) the date of termination of this Lease prior to the Expiration Date or (c) the vacating or abandonment of the Premises without termination of
this Lease; provided, however, that if Landlord so elects, in writing, prior to the Restoration Date, such alterations, additions, installations, improvements, partitions and Cabling (other than trade fixtures and personal property of Tenant) shall
become the property of Landlord as of the Restoration Date and shall be delivered to the Landlord with the Premises, and title thereof shall pass to Landlord upon such delivery as if by bill of sale. All shelves, bins, machinery and trade fixtures
installed by Tenant shall be removed by Tenant by the Restoration Date. All such removals and restoration shall be accomplished in a good workmanlike manner and shall not damage the primary structure or structural qualities of the Building. All
obligations of Tenant to restore the Premises shall be subject to the rights and obligations of the parties in the event of (a) the occurrence of a casualty covered by Paragraph 12(b), condemnation pursuant to Paragraph 15 and any breach of
this Lease by either party not cured within applicable cure periods. 
 8. Signs/Window Coverings. All signage visible
from the exterior of the Premises shall, at all times, comply with Exhibit D. Tenant shall not, without the prior written consent of Landlord, install or affix any window coverings, draperies, signs, window or door lettering or advertising
media of any type on the Property, the Building or in or on the Premises that are visible from the exterior of the Building. Tenant shall remove any permitted signs and window coverings, but not blinds, not later than the Restoration Date. Any such
installations and removals shall be made in such manner as to avoid injury or defacement of the Building and other improvements, and Tenant shall repair any injury or defacement, including, without limitation, discoloration caused by such
installation and/or removal. 
 9. Inspection. Landlord and Landlord’s agents and representatives shall have the
right to enter and inspect the Premises upon prior notice (which may be verbal notice) given at least one (1) business day prior to Landlord’s entry for the purpose of ascertaining the condition of the Premises or in order to make such
repairs and perform such actions as may be required or permitted to be made by Landlord under the terms of this Lease. Notwithstanding the foregoing, in the event of an emergency, Landlord shall have the right to enter the Premises without notice to
Tenant and shall not be liable to Tenant for any damage to person or property caused as a result of such entry; provided however that Landlord shall make reasonable efforts to communicate with Tenant prior to such emergency entry. In addition to the
foregoing, Landlord and Landlord’s agents and representatives shall also have the right to enter the Premises upon prior notice (which may be verbal notice) given at least one (1) business day prior to Landlord’s entry for the purpose
of showing the Premises to prospective purchasers and/or lenders and, during the period that is nine (9) months prior to the end of the Term, Landlord and Landlord’s agents shall have the right to erect a sign on the Premises indicating
the Premises are available for lease. 
 10. Utilities. Tenant shall pay for all water, gas, heat, light, power,
telephone, sewer and sprinkler charges and other utilities and services separately metered for the Premises, together with any taxes, penalties, surcharges or the like pertaining thereto and shall furnish and install all replacement electric light
bulbs and tubes. Landlord shall not be liable for any interruption or failure of utility services, communications or data services serving the Building or the Premises arising from any cause whatsoever. 

  
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 11. Assignment and Subletting. 

(a) Assignment and Subletting. Tenant shall not have the right to assign or pledge this Lease or to sublet the
whole or any part of the Premises, whether voluntarily or by operation of law, or permit the use or occupancy of the Premises by anyone other than Tenant, without the prior written consent of Landlord, which consent shall not be unreasonably
withheld, and such restrictions shall be binding upon any assignee or subtenant to which Landlord has consented. The foregoing prohibition includes, without limitation, any subletting or assignment that would otherwise occur by merger,
consolidation, reorganization, transfer or other change in Tenant’s corporate, partnership or other proprietary structure. Notwithstanding any permitted assignment or subletting, Tenant shall at all times remain directly, primarily and fully
responsible and liable for the payment of the Rent and for compliance with all of its other obligations under the terms, provisions and covenants of this Lease. If Tenant assigns this Lease or sublets all or a portion of the Premises without first
obtaining Landlord’s consent, as required by this Paragraph 11(a), said assignment or sublease shall be null and void and of no force or effect. Landlord’s consent to an assignment, sublease or other transfer of any interest of Tenant in
this Lease or in the Premises shall not be deemed to be a consent to any subsequent assignment, transfer, use or occupation. For the purposes of this Paragraph 11, Landlord shall be deemed to have acted reasonably if it withholds its consent to a
proposed assignment or sublease if (i) the creditworthiness of the proposed assignee or sublessee is less than the greater of (A) Tenant’s net worth as of the date of this Lease; or (B) a net worth of at least the net worth of
tenants to whom Landlord is then in the process of leasing similar square footage in the Building, it being understood and agreed that if Landlord is then requiring new tenants of such similar spaces to enhance their credit by virtue of security
deposits, letters of credit or similar vehicles, Landlord may require that the proposed assignee or sublessee comply with such credit enhancement requirements; and/or (ii) the assignee or sublessee is a tenant of Landlord in the Building or a
prospective tenant of the Building then working with Landlord or Landlord’s leasing agent. Landlord shall have no obligation to review or agree to any assignment or sublease request if Tenant is then in default under this Lease. 

(b) Payment of Rent to Landlord by Subtenant. Upon the occurrence of an Event of Default, if the Premises or any
part thereof are then sublet, Landlord, in addition to any other remedies herein provided or provided by law, may, at its option, collect directly from any subtenant all amounts due and becoming due to Tenant under such sublease and apply such
amounts against any sums due to Landlord from Tenant hereunder, and no such collection shall be construed to constitute a novation or release of Tenant from the further performance of Tenant’s obligations hereunder. Landlord’s acceptance
of any Rent following any assignment or other transfer prohibited by this Paragraph 11 shall not be deemed to be a consent by Landlord to such assignment or other transfer (including, without limitation, a prohibited sublease) nor shall the same be
deemed a waiver of any right or remedy of Landlord hereunder for breach of this Paragraph 11. 
 (c)
Costs. If Landlord grants its consent to any sublease or assignment, and the base rent payable by the assignee or subtenant exceeds the Base Rent then payable under this Lease, Tenant shall pay Landlord, as Additional Rent (i) fifty
percent (50%) of such excess net of Tenant’s actual costs payable to third parties to obtain such sublease or assignment and (ii) Landlord’s reasonable out of pocket costs, including attorneys’ fees and costs, with respect
to Landlord’s review and approval or disapproval of any proposed assignment or sublease. In addition, if Tenant has any options to extend or renew the Term, such options shall not be available to any subtenant or assignee, directly or
indirectly. Tenant shall, at Tenant’s own cost and expense, discharge in full any outstanding commission obligation on the part of Landlord with respect to this Lease, and any commissions that may be due and owing as a result of any proposed
assignment or subletting, whether or not the Premises are recaptured pursuant to subparagraph (d) below and rented by Landlord to the proposed tenant or any other tenant. 

(d) Right of Recapture. In addition, but not in limitation of, Landlord’s right to approve of any subtenant or
assignee, Landlord shall have the option, in its sole discretion, in the event of any proposed subletting or assignment, to terminate this Lease, or in the case of a proposed subletting of less than the entire Premises, to recapture the portion of
the Premises to be sublet, as of the date the subletting or assignment is to be effective. The option shall be exercised, if at all, by Landlord giving Tenant written notice thereof within thirty (30) days following Landlord’s receipt of
Tenant’s written notice as required above. If this Lease shall be terminated with respect to the entire Premises pursuant to this subparagraph, the Term shall end on the date stated in Tenant’s notice as the effective date of the sublease
or assignment as if that date had been the Expiration Date. If Landlord recaptures only a portion of the Premises under this subparagraph, the Base Rent during the remainder of the Term shall abate proportionately based on the Base Rent payable
hereunder as of the date immediately prior to such recapture. 
 12. Fire and Casualty Damage. 

(a) Notice of Casualty. If the Building should be damaged or destroyed by casualty, Tenant shall give immediate
oral and written notice thereof to Landlord’s Managing Agent. 

  
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 (b) Termination of Lease. If the Building should be damaged or
destroyed by casualty, or if it should be so damaged thereby that rebuilding or repairs cannot in Landlord’s estimation be completed within two hundred (200) days after the date upon which Landlord is notified by Tenant of such damage,
Landlord shall notify Tenant thereof and this Lease shall automatically terminate and Base Rent and Operating Costs shall be abated during the unexpired portion of this Lease, effective upon the date of the occurrence of such damage. 

(c) Repair of Premises. If the Building should be damaged by any peril covered by the insurance to be provided by
Landlord under Paragraph 14(a), but only to such extent that rebuilding or repairs can, in Landlord’s estimation, be completed within two hundred (200) days after the date upon which Landlord is notified by Tenant of such damage (except
that Landlord may elect not to rebuild if such damage occurs during the last year of the Term), Landlord shall notify Tenant thereof and this Lease shall not terminate, and Landlord shall, at its sole cost and expense, proceed with reasonable
diligence to rebuild and repair the Building to substantially the condition in which it existed prior to such damage, except that Landlord shall not be required to rebuild, repair or replace any part of the partitions, fixtures, additions and other
improvements that may have been placed in, on or about the Premises by Tenant. If the Premises are untenantable in whole or in part following such damage, Base Rent and Operating Costs payable hereunder during the period in which the Premises are
untenantable shall be reduced to such extent as may be fair and reasonable under all of the circumstances. In the event that Landlord should fail to complete such repairs and rebuilding within two hundred (200) days after the date upon which
Landlord is notified by Tenant of such damage (unless any such failure to complete is a Force Majeure Delay (as defined below) in which event such period shall be extended for the amount of time Landlord is so delayed on a business day for business
day basis), Tenant may at its option, upon thirty (30) days prior written notice, terminate this Lease as Tenant’s exclusive remedy, whereupon all rights and obligations of the parties to each other under this Lease shall cease and
terminate. For the purposes of this Lease, a “Force Majeure Delay” is a delay occurring, partially or wholly, as a result of delays caused by strikes, lockouts, boycotts or other labor problems, acts of war, acts of terrorism, acts of
nature, casualties, discontinuance of any utility or other service required for performance of the repair and restoration work, unavailability or shortages of materials or other problems in obtaining materials necessary for performance of the repair
and restoration work or any other matter beyond the control of Landlord or beyond the control of Landlord’s contractors or subcontractors performing such repair and restoration work. 

(d) Application of Proceeds. Notwithstanding anything herein to the contrary, in the event the holder of any
indebtedness secured by a mortgage or deed of trust covering the Premises or the Building requires that the insurance proceeds be applied to such indebtedness, Landlord shall have the right to terminate this Lease by delivering written notice of
termination to Tenant within fifteen (15) days after such requirement is made by any such holder, whereupon all rights and obligations of the parties to each other under this Lease shall cease and terminate. 

(e) Removal of Personal Property. In the event of any damage to the Building or the Premises by any peril
contemplated by this Paragraph 12, Tenant shall, promptly after the occurrence of such damage and at its sole cost and expense, remove from the Premises any personal property on the Premises belonging to any of Tenant, its agents, employees,
contractors, licensees or invitees. Tenant hereby indemnifies, holds harmless and agrees to defend Landlord from any loss, liability, damage, judgment, cost or expense, including attorneys’ fees incurred from the assertion of a claim, through
all appellate levels arising out of any claim of personal injury, bodily, injury, property damage or death by any of Tenant, its agents, employees, contractors, licensees or invitees as to itself or themselves or their respective properties arising
as a result of the removal or failure to remove such personal property. Landlord and Tenant agree that Landlord shall have no obligation to secure the Building or the Premises in the event of a casualty and that the risk of loss, by destruction,
theft or otherwise, to the personal property of Tenant, its agents, employees, contractors, licensees or invitees shall be borne, as between Landlord and Tenant, entirely by Tenant. 

(f) Business Interruption Waiver. Tenant waives all claims against Landlord for any damages for any loss that would
be covered by a policy of insurance in favor of Tenant covering business interruption for a period of at least 365 days. 

13. Reciprocal Indemnification; Waiver and Release. 

(a) Reciprocal Indemnification. Landlord shall not be liable for, and Tenant will indemnify and defend Landlord
from and against all losses, liabilities, claims, demands, suits, proceedings, judgments, costs, and expenses, (including attorneys’ fees), that result from any claim of injury or damage that arises in any manner from any occurrence in the
Premises or otherwise from Tenant’s use or occupancy of the Premises, whether or not Landlord is also indemnified by anyone else. Subject to the preceding sentence, Tenant shall not be liable for, and Landlord will indemnify and defend Tenant
from and against all losses, liabilities, claims, demands, suits, proceedings, judgments, costs, and expenses, (including attorneys’ fees), that result from any claim of injury or damage that arises in any manner from any occurrence in the
common areas of the Property outside of the Premises, whether or not Tenant is also indemnified by anyone else. Each of Landlord and Tenant acknowledges and agrees that this Paragraph 13(a) obligates it to indemnify and defend the other against the

  
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consequences of the indemnitee’s own negligence when the indemnitee is or is claimed to be jointly, comparatively, contributively, or concurrently negligent with the indemnitor, and when any
claim is based upon or alleged to be based upon the strict liability of the indemnitee. Any indemnitee has the right to participate in the defense of any indemnified claim at its own expense. 

(b) Waiver and Release. Except as provided in Paragraph 6 and below, each of Landlord and Tenant agrees to rely
entirely upon its own property insurance with respect to any damage, loss or injury to its property. 
 Each of
Landlord and Tenant hereby releases the other and the other party’s directors, officers, employees, agents and others acting on the other party’s behalf (collectively, the “released parties”) from all claims and all liability or
responsibility to the releasing party and to any person claiming through or under the releasing party, by way of subrogation or otherwise, for any loss or damage to the releasing party’s business or property caused by fire or other peril, even
if such fire or other peril was caused in whole or in part by the negligence or other act or omission of one or more of the released parties. Notwithstanding the foregoing, the release from liability and waiver or subrogation provided for shall
(i) only be effective to the extent that the loss or damage to the releasing party’s business or property is actually covered by insurance; and (ii) not apply to the extent of any deductible (or deductibles) that apply under such
insurance. 
 (c) Limitation of Liability. In no event shall a party ever be liable to the other party or
such party’s agents, servants or employees, or to any person or entity claiming by or through such party, for any consequential, indirect, special or similar types of damages; provided however that the parties agree that the foregoing
limitation shall not apply to consequential, indirect, special or other types of damages suffered by Landlord pursuant to Paragraph 16 hereof. 
 14. Insurance. 
 (a) Landlord’s Insurance.
Landlord shall maintain in effect at all times during the Term a policy or policies of insurance insuring the Building against loss or damage by fire, explosion or other insurable hazards and contingencies for the full replacement value. Landlord
shall not insure any personal property of Tenant or any additional improvements, which Tenant may construct or install on the Premises. Landlord may self-insure the exposures described above. Subject to the provisions of Paragraphs 12(b), 12(c) and
12(d), such insurance shall be for the sole benefit of Landlord and under its sole control. 
 (b)
Tenant’s Insurance. Tenant shall provide and maintain insurance as specified below. 
 (i) Insurance policies required by this Paragraph 14(b) shall be in a form reasonably acceptable to Landlord, with an insurer or insurers qualified to do business in the State of Minnesota with Financial
Performance rating of A+ and a Financial Size Category of VII (A+VII) or better in accordance with the current Best Key Rating
Guide®, Property Casualty, United States. Such policy(ies) shall require at least thirty (30) days prior
written notice to Landlord (and, if requested by Landlord, Landlord’s mortgagee(s)) and shall include a Notice of Cancellation Endorsement in form and substance reasonably acceptable to Landlord. All policies required shall be primary and
non-contributory to any other insurance available to Landlord. 
 (ii) Tenant shall, at its sole cost and
expense, maintain in effect at all times during the Term a commercial general liability insurance policy, on an “occurrence” rather than on a “claims made” basis, with a total combined policy limit of at least $2,000,000.00. The
policy shall include, but not be limited to, coverages for Bodily Injury, Property Damage, Personal Injury and Contractual Liability (applying to this Lease), or an equivalent form (or forms) affording coverage at least as broad. Landlord and
Landlord’s Managing Agent shall be named as Additional Insureds under the policy and Tenant shall deliver to Landlord an Additional Insured Endorsement to Tenant’s policy in form and substance satisfactory to Landlord naming Landlord,
Landlord’s Managing Agent and Landlord’s mortgagee(s), if any as additional insureds. No coverage shall be deleted from the standard policy without notification of individual exclusions being attached for review and acceptance by Landlord.
The liability insurance under this subparagraph 14(b)(ii) shall be primary with respect to Landlord and its agents and not participating with any other available insurance. 

(iii) Tenant shall, at its sole cost and expense, maintain in effect at all times during the Term, a policy or polices of
insurance covering all of Tenant’s improvements, fixtures, inventory and other personal property in the Premises against loss by fire and other hazards covered by an “all-risk” form of policy, in an amount equal to the full
replacement cost thereof, without deduction for physical depreciation. Such insurance shall include Valuable papers and Records coverage providing for the Reproduction Costs measure of recovery and coverage for damage to Electronic Data Processing
Equipment and Media, including coverage of the perils of mechanical breakdown and electronic disturbance. 

  
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 (iv) If the use of the Premises by Tenant increases the premium rate for
insurance carried by Landlord on the Building, Tenant shall pay Landlord, upon demand, as Additional Rent, the amount of such premium increase. 
 (v) Tenant, upon actual knowledge or receipt of written notice by Landlord, shall not carry any stock of goods, inventory, or Hazardous Substances (as defined in this Lease) or do anything in or about the
Premises that will in any way impair or invalidate the obligation of the insurer under any policy of insurance required by this Lease. 
 Prior to the Commencement Date, on each anniversary of the Commencement Date and at such other times as Landlord may request, Tenant shall deliver to Landlord evidence satisfactory to Landlord showing the
coverages and endorsements required to be provided hereunder are in full force and effect. 
 If Tenant has a
blanket insurance policy providing coverage for several properties of Tenant, including the Premises, Landlord will accept evidence of such insurance provided: 
 (1) the evidence is in form and substance satisfactory to Landlord and includes the Notice of Cancellation and Additional Insured endorsements required above; and 

(2) the policy complies with the other requirements in this Lease. 

15. Condemnation. 
 (a) Total Taking. If the whole or any substantial part of the Building is taken for any public or quasi-public use under governmental law, ordinance or regulation, or by right of eminent domain, or
by private purchase in lieu thereof and the taking would prevent or materially interfere with the use of the Premises or the Building for the Use, by notice given by Landlord to Tenant, this Lease shall terminate and the Base Rent and Operating
Costs shall be abated during the unexpired portion of this Lease effective as of the date the physical taking of the Property occurs. 
 (b) Partial Taking. If part of the Premises shall be taken for any public or quasi-public use under any governmental law, ordinance or regulation, or by right of eminent domain, or by private
purchase in lieu thereof, and this Lease is not terminated as provided in the subparagraph above, this Lease shall not terminate but the Base Rent and Operating Costs payable hereunder during the unexpired portion of this Lease shall be reduced to
such extent as may be fair and reasonable under all of the circumstances. 
 (c) Awards. In the event of
any such taking or private purchase in lieu thereof, Landlord and Tenant shall each be entitled to receive and retain such separate awards and/or portion of lump sum awards as may be allocated to their respective interests in any condemnation
proceedings, provided that Tenant shall not be entitled to receive any award for Tenant’s loss of its leasehold interest or other property that would have become the property of Landlord upon termination of this Lease; the right to such award
being hereby assigned to Landlord. 
 (d) Application of Proceeds. Notwithstanding anything herein to the
contrary, in the event the holder of any indebtedness secured by a mortgage or deed of trust covering the Premises or the Building requires that the award be applied to such indebtedness, Landlord shall have the right to terminate this Lease by
delivering written notice of termination to Tenant within fifteen (15) days after such requirement is made by any such holder, whereupon all rights and obligations of the parties to each other under this Lease shall cease and terminate.

 16. Holding Over. Tenant will, at the expiration or earlier termination of this Lease yield up immediate possession to
Landlord in the condition required by Exhibit E. If Tenant retains possession of the Premises or any part thereof after such expiration or termination, then, subject to the last sentence of this Paragraph, such holding over shall constitute
creation of a month to month tenancy, upon the terms and conditions of this Lease; provided, however, that the monthly rental for such holding over shall, in addition to all other sums that are to be paid by Tenant hereunder, whether or not as
Additional Rent, be equal to two hundred percent (200%) of the Rent being paid monthly to Landlord under this Lease immediately prior to such termination. In addition to and not in limitation of the foregoing, Tenant shall also pay to Landlord
all damages sustained by Landlord resulting from retention of possession by Tenant, including the loss of any proposed subsequent tenant for any portion of the Premises. The provisions of this Paragraph shall not constitute a waiver by Landlord of
any right of re-entry as herein set forth; nor shall receipt of any rental or other sums or any other act in apparent affirmance of the tenancy operate (a) as an extension of the Term; (b) a waiver of Landlord’s right to terminate
Tenant’s right to possession of the Premises; or (c) a waiver of the right to terminate this Lease for a breach of any of the terms, covenants, or obligations herein on Tenant’s part to be performed. 

  
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 17. Quiet Enjoyment. Landlord covenants that it now has, or will acquire before
Tenant takes possession of the Premises, insurable title to the Premises. Landlord represents and warrants that it has full right and authority to enter into this Lease and that Tenant, upon paying the Rent and performing its other covenants and
agreements under this Lease, shall peaceably and quietly have, hold and enjoy the Premises for the Term, subject to the terms and provisions of this Lease. 
 18. Events of Default. Each of the following events shall be deemed to be an Event of Default by Tenant under this Lease: 

(a) Tenant shall fail to pay any installment or other payment of Rent required herein when due, and such failure shall
continue for a period of five (5) days after such payment was due; ; provided however that if Tenant fails to pay any installment or other payment of Rent required herein when due, Tenant shall not be deemed in default of this Lease until five
(5) days after Landlord has notified Tenant, in writing, of such failure; but provided further that Landlord shall be required to give the notice described in the preceding clause only once in any twelve-month period, and Tenant’s failure
to pay any installment or other payment of Rent required herein within five (5) days from the date such payment was due, within twelve months after any such written notice given by Landlord pursuant to this subparagraph (a) shall
constitute an Event of Default under this Lease;; 
 (b) Tenant shall become insolvent, or shall make a transfer
in fraud of creditors, or shall make an assignment for the benefit of creditors; or a receiver or trustee shall be appointed for all or substantially all of the assets of Tenant; 

(c) Tenant shall file a petition under any section or chapter of the federal bankruptcy laws, or under any similar law or
statute of the United States or any State, including, without limitation, a liquidation, rehabilitation or other insolvency statute, whether now or hereafter in effect; or an order for relief shall be entered against Tenant in any such bankruptcy or
insolvency proceedings filed against Tenant thereunder or Tenant shall be adjudged bankrupt or insolvent in proceedings filed against Tenant thereunder; 
 (d) Tenant shall vacate or abandon all or a substantial portion of the Premises; provided however, that such vacation or abandonment shall not constitute a default hereunder unless, in Landlord’s
reasonable estimation, Tenant has failed to comply with its obligations to maintain the Premises as required under this Lease; 
 (e) Tenant shall fail to discharge any lien placed upon the Premises in violation of Paragraph 22 hereof; 
 (f) Tenant shall fail to insure and provide evidence of such insurance in accordance with Paragraph 14(b); and 
 (g) Tenant shall fail to pay Tenant’s Restoration Share as set forth in Paragraph 31 hereof; and 
 (h) Tenant shall fail to comply with any term, provision or covenant of this Lease (other than the foregoing in this Paragraph 18), and shall not cure such failure within 30 days after written notice
thereof from Landlord to Tenant, provided that Tenant promptly commences and diligenty pursues a cure in good faith for a period not to exceed 60 days after the date of written notice. 

19. Remedies. Upon the occurrence of any one or more of the Events of Default described in Paragraph 18 hereof, Landlord shall
have the option to pursue any one or more of the following remedies without any further notice or demand whatsoever. 
 (a) Landlord may, at its election, terminate this Lease or terminate Tenant’s right to possession only, without terminating this Lease; 

(b) Upon any termination of this Lease, whether by lapse of time or otherwise, or upon any termination of Tenant’s
right to possession without termination of this Lease, Tenant shall surrender possession and vacate the Premises immediately and deliver possession thereof to Landlord in the condition required by Exhibit E hereof, and Tenant hereby grants to
Landlord full and free license to enter into and upon the Premises in such event with or without process of law and to repossess Landlord of the Premises as of Landlord’s former estate and to expel or remove Tenant and any others who may be
occupying or within the Premises and to alter all locks and other security devices at the Premises and to remove any and all property therefrom, without being deemed in any manner guilty of trespass, eviction or forcible entry or detainer, and
without incurring any liability for any damage resulting therefrom. Tenant hereby waives any right to claim damage for such re-entry and expulsion, and such entry and possession shall not terminate this Lease or release Tenant, in whole or in part,
from any obligation, including Tenant’s obligation to pay all Rent payable by Tenant hereunder, for the Term or any other right given to Landlord hereunder or by operation of law; 

  
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 (c) Landlord may, but need not, relet the Premises or any part thereof for
such Rent and upon such terms as Landlord, in its sole discretion, shall determine (including the right to relet the Premises as part of a larger area and the right to change the character or the use made of the Premises), and Landlord shall not be
required to accept any tenant offered by Tenant or to observe any instructions given by Tenant about such reletting. In any such case, Landlord may make repairs, alterations and additions in or to the Premises, and redecorate the same to the extent
Landlord deems necessary or desirable, in its sole discretion. All Rent and other sums received by Landlord from any such reletting shall be applied as follows: first, to the payment of any indebtedness other than Rent due hereunder from Tenant to
Landlord; second, to the payment of any costs and expenses of such alterations and repairs; third, to the payment of Landlord’s expenses of reletting, including, without limitation, broker’s commissions, reasonable attorneys’ fees and
costs and lease inducements, such as moving or leasehold improvement allowances; fourth, to the payment of Rent due and unpaid hereunder; and the residue, if any, shall be held by Landlord and applied in payment of future Rent as the same may become
due and payable hereunder. If such Rent and other sums received from such reletting during any month be less than the Rent to be paid during said month by Tenant hereunder, Tenant shall pay such deficiency to Landlord within ten (10) days after
Landlord’s written demand therefor. Such deficiency shall be calculated and paid monthly or at other intervals as Landlord, in its sole discretion, may determine, but not more frequently than monthly. Notwithstanding any such re-entry by
Landlord, Landlord may at any time hereafter elect to terminate this Lease for such previous breach. 
 (d)
Tenant acknowledges that the damages Landlord would incur in connection with terminating this Lease following an Event of Default by Tenant would be difficult to estimate or ascertain. Therefore, Tenant agrees that, in the event Landlord elects to
terminate this Lease, Landlord may, in addition to other remedies available at law or in equity, declare all Rent payable under this Lease immediately due and payable and recover from Tenant, as liquidated damages, and not as a penalty, an amount
equal to the sum of the following: (i) all unpaid Rent that is payable by Tenant hereunder and that accrues through the effective date of termination; plus (ii) the “Tenant’s Restoration Share”, as Paragraph 31 of this Lease
defines that term; plus (iii) the cost of repairs, alterations and/or redecoration of the Premises that Landlord reasonably determines are necessary to make the Premises suitable for reletting, but not including the cost of removing the
“Improvements”, as Paragraph 31 of this Lease defines that term; plus (iv) a sum of money equal to the entire amount of Rent that would be payable under this Lease for the lesser of (A) the three (3) year period commencing
upon the effective date of termination, or (B) the period commencing upon the effective date of termination and ending upon the original Expiration Date (as the same may have been extended), which amount shall be immediately due and payable
upon demand, but which amount shall be discounted to present value using a discount rate equal to the discount rate of the Federal Reserve Bank of Minneapolis as of the effective date of termination plus one percent (1%). For purposes of calculating
the amount of Rent that would be payable under this Lease for the period succeeding the effective date of termination, such Rent shall be computed on the basis of the average monthly amount of Rent accruing during the twenty-four (24) month
period immediately preceding the default to which such termination relates (exclusive of any months in which Tenant received “free” or abated Base Rent concessions); provided, however, if the default occurs prior to the expiration of the
first twenty-four (24) months of this Lease, then the Rent shall be computed on the basis of the average monthly amount of Rent accruing during all months preceding the month in which said default occurred (exclusive of any months in which
Tenant received “free” or abated Base Rent concessions). 
 (e) Any and all property that may be
removed from the Premises by Landlord pursuant to the authority of this Lease or of law, to which Tenant is or may be entitled, may be left at the Premises, handled, removed and stored, as the case may be, by or at the direction of Landlord, in
Landlord’s sole discretion, at the risk, cost and expense of Tenant, and Landlord shall in no event be responsible for the value, preservation or safekeeping thereof. Tenant shall pay to Landlord, upon demand, any and all expenses incurred in
such removal and all storage charges against such property (even if left at the Premises) so long as the same shall be in Landlord’s possession or under Landlord’s control. Any such property of Tenant not retaken by Tenant from storage
within thirty (30) days after removal from the Premises shall, at Landlord’s option, be deemed conveyed by Tenant to Landlord under this Lease as by a bill of sale without further payment or credit by Landlord to Tenant. 

(f) Pursuit of any of the foregoing remedies shall not preclude pursuit of any of the other remedies herein provided or
any other remedies provided by law, nor shall pursuit of any remedy herein provided constitute a forfeiture or waiver of any Rent due to Landlord hereunder or of any damages accruing to Landlord by reason of the violation of any of the terms,
provisions and covenants herein contained. No act or thing done by the Landlord or its agents during the Term shall be deemed a termination of this Lease or an acceptance of the surrender of the Premises, and no agreement to terminate this Lease or
accept a surrender of said Premises shall be valid unless in writing signed by Landlord. No waiver by Landlord of any violation or breach of any of the terms, provisions and covenants herein contained shall be deemed or construed to constitute a
waiver of any other violation or breach of any of the terms, provisions and covenants herein contained. Landlord’s acceptance of the payment of Rent or other payments hereunder after the occurrence of an Event of Default shall not be construed
as a waiver of such default, unless Landlord so notifies Tenant in writing. Forbearance by Landlord to enforce one or more of the remedies herein provided upon an Event of Default shall not be deemed or construed to constitute a waiver of such
default or of Landlord’s right to enforce any such remedies with respect to such default or any subsequent default. 

  
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 20. Intentionally Left Blank. 

21. Mortgages. This Lease is and shall be subject and subordinate to any mortgage(s) now or at any time hereafter constituting a
lien or charge upon the Property or the Premises, provided, however, that if the holder of any such mortgage elects to have Tenant’s interest in this Lease superior to any such instrument, then by notice to Tenant from such holder, this Lease
shall be deemed superior to such lien, whether this Lease was executed before or after said mortgage. Tenant shall at any time hereafter on demand execute any instruments, releases or other documents that may be required by any mortgagee for the
purpose of subjecting and subordinating this Lease to the lien of any such mortgage. Landlord represents and warrants to Tenant that, as of the Date of Lease, there is no mortgage, deed of trust, similar security instrument or ground lease affecting
the Building or the Project. 
 22. Mechanic’s Liens. Tenant shall keep the Premises and the Property free from any
mechanics’, materialmen’s, contractors’ or other liens arising from, or any claims for damages growing out of, any work performed, materials furnished or obligations incurred by or on behalf of Tenant. If such a lien is filed against
the Premises or the Property or any portion thereof as a result of work performed, materials furnished or obligations incurred by or on behalf of Tenant, Tenant, at its sole cost and expense, shall cause such lien to be removed within 30 calendar
days after Tenant becomes aware of the filing of such lien. Tenant hereby agrees to defend and indemnify Landlord and to hold Landlord harmless from and against any such lien or claim or action thereon, and shall reimburse Landlord, as Additional
Rent for Landlord’s costs of suit and all attorneys’ fees and costs incurred in connection any such lien, claim or action. Landlord hereby reserves the right, at any time and from time to time during the construction of the Premises or any
subsequent alteration to enter onto the Premises and post and review notices in accordance with Minn. Stat. §514.06, as the same may be amended. 
 23. Notices. All Rent payments, bills, statements, notices or communications, required or desired to be given hereunder shall be in writing and shall be deemed given, effective and received (the
“Effective Date of Notice”) (a) upon personal delivery; (b) five (5) days after deposit in the United States mail, certified mail, return receipt requested, postage prepaid; or (c) one (1) business day after
deposit with a national overnight air courier, fees prepaid, to Landlord or Tenant, as the case may be, at the notice or Rent payment addresses for each party stated on the Data Sheet. Either party may designate an additional or another address upon
giving written notice to the other party at the address for notices for such party stated on the Data Sheet pursuant to this Paragraph 23. Any return of any access cards or keys or other similar devices shall be made to Landlord’s Managing
Agent, at the address stated on the Data Sheet or such other address as may be provided pursuant to this Paragraph 23. Landlord’s Managing Agent shall give and receive notices in the manner prescribed by this Paragraph, and a copy of all
notices given to Landlord shall be given to Landlord’s Managing Agent in the manner prescribed by this Paragraph 23. For the purposes of this Lease, “business day” shall mean a day that is not a Saturday, a Sunday or a legal holiday
of the State of Minnesota. 
 If and when included within the term “Landlord,” as used in this instrument, there are
more than one person, firm or corporation, all shall jointly arrange among themselves for their joint execution of such a notice specifying some individual at some specific address for the receipt of notices and payments to Landlord; if and when
included within the term “Tenant,” as used in this instrument, there are more than one person, firm or corporation, all shall jointly arrange among themselves for their joint execution of such a notice specifying some individual at some
specific address within the continental United States for the receipt of notices and payments to Tenant. All parties included within the terms “Landlord” and “Tenant,” respectively, shall be bound by notices given in accordance
with the provisions of this paragraph to the same effect as if each had received such notice. 
 24. Hazardous
Substances. Tenant shall at all times comply with all applicable local, state and federal laws, ordinances and regulations relating to Hazardous Substances. “Hazardous Substances” means (1) any oil, petroleum product, flammable
substances, explosives, radioactive materials, hazardous wastes or substances, toxic wastes or substances, infectious wastes or substances or any other wastes, materials or pollutants that (A) pose a hazard to the Premises, Building or Property
or to persons on or about the Premises, Building or Property or (B) cause the Premises, Building or Property to be in violation of any hazardous materials laws; (2) asbestos in any form, urea-formaldehyde foam insulation, transformers or
other equipment that contains dielectric fluid containing polychlorinated biphenyl, or radon gas; (3) any chemical, materials or substance defined as or included in the definition of “hazardous substances,” “hazardous
wastes,” “hazardous materials,” “extremely hazardous waste,” “restricted hazardous waste,” “infectious waste,” or “toxic substances,” or words of similar import under any applicable local, state
or federal law or under the regulations adopted or publications promulgated pursuant thereto, including, but not limited to, the Comprehensive Environmental Response, Compensation and Liability Act of 1980, as amended, 42 U.S.C. §§ 9601,
et seq.; the Hazardous Materials Transportation Act, as amended, 42 U.S.C. §§ 6901, et seq.; the Federal Water Pollution Control Act, as amended, 33 U.S.C. §§ 1251, et seq.; (4) any
other chemical, material or substance, exposure to which is prohibited, limited or regulated by any governmental authority or may or could pose a hazard to the health and safety of the occupants of the Premises, Building or Property or the owners
and/or occupants of property adjacent to or surrounding the Property, or any other person or entity coming upon the Property or adjacent property; and (5) any other chemical, material or substance that may or could pose a hazard to the
environment. Tenant shall not: (i) use the Premises, 

  
 12 

 
Building or Property for the storage of Hazardous Substances except for such activities that are part of the course of tenant’s ordinary business (the “Permitted Activities”);
provided, such Permitted Activities are conducted in accordance with all applicable laws, orders, regulations and ordinances and have been approved in advance in writing by Landlord; (ii) use the Premises, Building or Property as a landfill or
dump; or (iii) install any underground tanks of any type at the Property. Tenant shall at its own expense maintain in effect any and all permits, licenses or other governmental approvals, if any, required for Tenant’s use of the Premises
and require the same of any subtenants. Tenant shall make and cause any subtenant to make all disclosures required of Tenant by any laws, and shall comply and cause subtenant to comply with all orders concerning Tenant’s use of the Premises
issued by any governmental authority having jurisdiction over the Premises and take all action required by such governmental authorities to bring the Tenant’s activities on the Premises into compliance with all environmental and other laws,
rules, regulations and ordinances affecting the Premises. If at any time Tenant shall become aware, or have reasonable cause to believe, that any Hazardous Substance has been released or has otherwise come to be located on or beneath the Property,
Tenant shall give written notice of that condition to Landlord immediately after Tenant becomes so aware. Tenant shall be responsible for, and shall indemnify, defend and hold Landlord harmless from and against, all environmental claims, demands,
damages and liabilities, including, without limitation, court costs and reasonable attorney fees, if any, arising out of, or in connection with, the generation, storage, disposal or other presence of any Hazardous Substance in, on or about the
Premises, Building or Property during the Term or that Tenant or its subtenants caused or permitted. The indemnification provided by this Paragraph 24 shall survive the expiration or earlier termination of this Lease. 

25. Expense of Enforcement. If either party commences an action against the other to enforce this Lease or because of the breach
by either party of this Lease, or if Landlord seeks enforcement against any assignee or subtenant or any guarantor of Tenant’s obligations under this Lease, the prevailing party in such action shall be entitled to recover reasonable attorney
fees, costs, and expenses (including expert fees and costs) incurred in connection with the prosecution or defense of such action, including any appeal, in addition to all other relief. To the extent Tenant is the non-prevailing party,
attorneys’ fees and costs payable by Tenant under this paragraph shall be payable by Tenant to Landlord with the next installment of Rent falling due and shall constitute Additional Rent hereunder. For the purposes of this Lease,
“prevailing party” shall mean the party that obtains the principal relief it has sought, whether by compromise, settlement, judgment or otherwise. In addition, the non-prevailing party shall be responsible for payment of any and all actual
third party costs and/or expenses (including, without limitation, reasonable attorney’s fees and expert fees) incurred by the prevailing party in the enforcement of any of its rights and/or remedies under this Lease, at law or in equity.

 26. Intentionally Left Blank. 
 27. Transfer of Landlord’s Interest; Limitation of Liability. 
 (a) Transfer of Landlord’s Interest. The term “Landlord” shall mean only the owner, at any time of the Property, and in the event of the transfer by such owner of its interest in the
Property, such owner’s grantee or successor shall upon such transfer, become “Landlord” under this Lease. If any owner transfers its interest in the Premises or the Property or any portion thereof, other than a transfer for security
purposes, such owner shall automatically be relieved of any and all obligations and liabilities on the part of such owner as “Landlord” accruing after the date of such transfer, including, without limitation, such owner’s obligation
to return the Security Deposit following assignment or transfer thereof to such owner’s transferee. 
 (b)
Limitation of Landlord’s Liability. If Landlord is ever adjudged by any court to be liable to Tenant, Tenant specifically agrees to look solely to Landlord’s interest in the Phase for the recovery of any judgment from Landlord, it
being agreed that none of Landlord, its directors, officers, shareholders, managing agents, employees or agents shall be personally liable for any such judgment. In no event shall Landlord ever be liable to Tenant, Tenant’s agents, servants or
employees, or to any person or entity claiming by or through Tenant, for any consequential, indirect, special or similar types of damages. 
 28. Right of Landlord to Perform. If Tenant shall fail to pay any sum of money other than Rent required to be paid by it under this Lease, or shall fail to perform any other act on its part to be
performed under this Lease, Landlord may, but shall not be so obligated, and without waiving or releasing Tenant from any obligations of Tenant, after the end of the tenth (10th) calendar day after the Effective Date of Notice of notice to Tenant specifying Tenant’s obligation to
perform, make any such payment or perform any such other act on Tenant’s part to be made or performed; provided, however, that in the event of emergency, Landlord shall have the right to perform Tenant’s obligations prior to the expiration
of the ten (10) day period specified above. If Landlord performs Tenant’s obligations pursuant to this Paragraph 28, Landlord shall have the right to use the Security Deposit to pay such expenses, or pay such expenses directly and
reimburse itself from the Security Deposit or to the extent the cost of such performance exceeds the Security Deposit, Landlord may pay for the cost of such performance from its own funds, or from a combination of the Security Deposit and its own
funds and all such amounts shall be repaid to Landlord by Tenant as Additional Rent, payable with the next installment of Base Rent falling due. 

  
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 29. Miscellaneous. 

(a) Gender; etc. Words of any gender used in this Lease shall be held and construed to include any other gender,
and words in the singular number shall be held to include the plural, unless the context otherwise requires. 

(b) Binding Effect. The terms, provisions and covenants and conditions contained in this Lease shall apply to,
inure to the benefit of, and be binding upon, the parties hereto and upon their respective heirs, legal representatives, successors and permitted assigns, except as otherwise herein expressly provided. Tenant shall deliver promptly upon demand, a
corporate resolution, proof of due authorization by partners, or other appropriate documentation evidencing the due authorization of Tenant to enter into this Lease. Nothing herein contained shall give any other tenant in the Building any
enforceable rights against either Landlord or Tenant as a result of the covenants and obligations of either party stated herein. 
 (c) Captions. The captions inserted in this Lease are for convenience only and in no way define, limit or otherwise describe the scope or intent of this Lease, or any provision hereof, or in any
way affect the interpretation of this Lease. 
 (d) Estoppel. Tenant agrees from time to time within ten
(10) days after the Effective Date of Notice of request by Landlord, to deliver to Landlord, or Landlord’s designee an estoppel certificate in a form designated by Landlord. It is understood and agreed that Tenant’s obligation to
furnish such estoppel certificates in a timely fashion is a material inducement for Landlord’s execution of this Lease, and that, if Tenant fails timely to deliver any estoppel certificate contemplated by this subparagraph (d), Tenant shall be
liable to Landlord for all losses incurred by Landlord as a result of such failure, including, without limitation, attorneys’ fees and court costs through all appellate levels. 

(e) Amendment. This Lease may not be altered, changed or amended except by an instrument in writing signed by both
parties hereto. 
 (f) Survival of Obligations. All obligations of Tenant hereunder not fully performed as
of the expiration or earlier termination of the Term shall survive the expiration or earlier termination of the Term, including without limitation, all payment obligations with respect to Operating Costs and all obligations concerning the condition
of the Premises. Upon the expiration or earlier termination of the Term, Tenant shall pay to Landlord the amount as estimated by Landlord, necessary (i) to bring the Premises into the condition required by Exhibit E; and (ii) to
discharge Tenant’s obligation for Operating Costs or other amounts due Landlord. All such amounts shall be used and held by Landlord for payment of such obligations of Tenant, with Tenant being liable for any additional costs upon demand by
Landlord, or with any excess to be returned to Tenant after all such obligations have been determined and satisfied. Any security deposit held by Landlord shall be credited against the amount payable by Tenant under this subparagraph. 

(g) Joint and Several. If there be more than one person or entity comprising Tenant, the obligations hereunder
imposed upon Tenant shall be joint and several. 
 (h) Brokers. Tenant represents and warrants that it has
dealt with no broker, agent or other person in connection with this transaction or that no broker, agent or other person brought about this transaction, other than Tenant’s Broker, if any, listed on the Data Sheet, and Tenant agrees to defend,
indemnify and hold Landlord harmless from and against any claims by any other broker, agent or other person claiming a commission or other form of compensation by virtue of having dealt with Tenant with regard to this leasing transaction.

 (i) Severability. If any clause or provision of this Lease is illegal, invalid or unenforceable under
present or future laws effective during the Term, then and in that event, it is the intention of the parties hereto that the remainder of this Lease shall not be affected thereby, and it is also the intention of the parties to this Lease that in
lieu of each clause or provision of this Lease that is illegal, invalid or unenforceable, there be added as a part of this Lease a clause or provision as similar in terms to such illegal, invalid or unenforceable clause or provision as may be
possible and be legal, valid and enforceable. 
 (j) Offer to Lease. Because the Premises are on the open
market and are currently being shown, this Lease shall be treated as an offer and shall not be valid or binding unless and until accepted by Landlord in writing. 

(k) Waiver of Jury Trial; Jurisdiction. EACH OF LANDLORD AND TENANT HEREBY WAIVES ANY RIGHT TO A TRIAL BY JURY IN
ANY ACTION RELATING TO THIS LEASE. At the option of Landlord, this Lease shall be enforced in any United States District Court for the Federal District of Minnesota or state court of the State of Minnesota sitting in Hennepin County, Minnesota, and
Tenant consents to the jurisdiction and venue of any such court and waives any argument that venue in such forums is not proper or convenient. 

  
 14 

 (l) Complete Agreement. This Lease contains all of the agreements and
understandings relating to the leasing of the Premises and the obligations of Landlord and Tenant in connection with such leasing. Landlord has not made, and Tenant is not relying upon, any warranties or representations, promises or statements made
by Landlord or any agent of landlord, except as expressly stated herein. This Lease supersedes any and all prior agreements and understandings between Landlord and Tenant and alone expresses the agreement of the parties. 

(m) Governing Law. This Lease, the rights of the parties hereunder and the interpretation hereof shall be governed
by, and construed in accordance with, the internal laws of the State of Minnesota, without giving effect to conflict of laws principles thereof. 
 (n) Construction. The parties agree that counsel for both parties have reviewed this Agreement. Accordingly, neither party shall be deemed to have drafted this Agreement and it shall not be
construed against either party by virtue of the drafting thereof in the event of a dispute. 
 (o) Time of
Essence. Time shall be of the essence with respect to this Lease and each and every provision hereof. 
 30.
Exhibits. Exhibits A, B, C, D, E and F attached hereto are hereby incorporated herein by reference. 
 31. Removal of
Existing Improvements. 
 (a) The parties acknowledge and agree that, as of the date of this Lease:

 (i) The Premises contain certain specialized improvements as depicted on Exhibit F
(“Improvements”) placed therein by the two previous tenants of the Premises and used by Tenant. 
 (ii)
Under the Sublease, Tenant is obligated to pay GenMab a portion of the cost of removing the Improvements at the end of the term of the Sublease unless Tenant enters into a lease of the Premises directly with Landlord that commences upon the
expiration of the term of the Sublease. 
 (iii) The existence of the Improvements is of critical importance to
Tenant in leasing the Premises pursuant to this Lease, and that, but for the existence of the Improvements, Tenant would not enter into this Lease. 
 (iv) Landlord would not enter into this Lease unless Tenant agrees to pay for part of the cost of removing the Improvements upon the expiration of this Lease. 

(v) Tenant shall pay $180,000 (“Tenant’s Restoration Share”) towards the cost of the removal of the
Improvements and the restoration of the Premises to Landlord on the earlier of (A) the date of termination of this Lease prior to the Expiration Date; or (B) within sixty (60) days prior to the expiration of the Term. Tenant has no
obligation to remove the Improvements at or before the end of the Term, and Tenant has no right to reduce or avoid paying the Tenant’s Restoration Share to Landlord by removing any or all of the Improvements at any time. 

(vi) notwithstanding anything to the contrary in Paragraph 19 of this Lease, in the event of adefault by Tenant under this
Paragraph 31, the calculation of damages set forth in Paragraph 19(d)(iii) of this Lease shall not include Tenant’s Restoration Share, which shall be paid to Landlord in full, together with any amounts payable under said Paragraph 

19(d)(iii). 
 (b) Nothing in this Paragraph shall be deemed to excuse Tenant, at its sole cost and expense, from restoring the Premises to the condition required by Exhibit E as to those matters not covered by
the any bid received by Landlord for the cost of restoration of the Premises. 

  
 15 

 IN WITNESS WHEREOF, the parties have executed this Lease as of the Date of Lease.

  

									
	ST. PAUL FIRE AND MARINE INSURANCE COMPANY	  		  	BIOAMBER INC.
					
	By:	  	 /s/ Michael D. Elnicky
	  		  	By:	    	 /s/ Jean François-Huc

		  	Name:    Michael D. Elnicky	  		  		    	Name:    J.F. Huc
		  	Title:      Asset Manager	  		  		    	Title:      CEO

  
 16 

 EXHIBIT A 
 DEPICTION OF PREMISES 
 

 
  

  
 A-1

 EXHIBIT B 
 RULES AND REGULATIONS FOR 
 PLYMOUTH BUSINESS CENTER 

1. The sidewalks, passages and stairways, if any, shall not be obstructed by Tenant or used for any purpose other than for ingress to and
egress from the Premises. The passages, entrances, stairways, if any, and roof are not for the use of the general public, and Landlord shall in all cases retain the right to control and prevent access thereto of all persons whose presence in the
judgment of Landlord shall be prejudicial to the safety, character, reputation and interests to the Building and its tenants; provided that nothing herein contained shall be construed to prevent such access to persons with whom Tenant normally deals
in the ordinary course of its business unless such persons are engaged in illegal activities. None of Tenant, its employees, agents or contractors shall go upon the roof of the Building without the prior written consent of the Landlord. 

2. The sashes, sash doors, windows, glass lights and any lights or skylights that reflect or admit light into halls, from the building
exterior or other places into the building shall not be covered or obstructed. Any curtains, blinds, shades, or screens attached or hung to any of the prior mentioned areas must have prior approval of Landlord. Landlord will provide standard window
coverings on exterior windows and other glass if appropriate and Landlord reserves the right to regulate position of such coverings. 
 3. In case of invasion, act of war, act of terrorism, riot, public excitement or other commotion, Landlord reserves the right to prevent access to the Building during the continuance of same. Landlord
shall in no case be liable for damages for the admission or exclusion of any person or equipment to or from the Building. Landlord has the right to evacuate the Building in the event of an emergency or catastrophe. 

4. Two door keys for doors to leased premises shall be furnished at the commencement of a lease by Landlord. All duplicate keys shall be
purchased only from the Landlord. One security card per each of Tenant’s employees so authorized by Tenant will be issued for all approved personnel to permit afterhours access, and Landlord reserves the right to assess a fee to Tenant for the
replacement of lost keys or cards. Tenant shall not alter any lock, or install new or additional locks or bolts, on any door without the prior written approval of Landlord. In the event such alteration or installation is approved by Landlord, Tenant
shall supply Landlord with a key for any such lock or bolt. Tenant, upon the termination of the tenancy, shall deliver to Landlord all the keys, locks, bolts, cabinets, safes or vaults, or the means of opening any lockable device and security cards
of offices, rooms and toilet rooms that shall have been furnished Tenant or that Tenant shall have had made, and in the event of loss of any keys or security cards so furnished shall pay the Landlord therefor. 

5. All deliveries, including intra company deliveries, must be made via service entrances. Tenant agrees to adhere to floor loading
maximum levels as stated by Landlord. All damage done to the Building by the delivery or removal of such items, or by reason of their presence in the Building, shall be paid to Landlord upon demand by Tenant and shall constitute Additional Rent,
payable upon demand, under this Lease. 
 6. Parking area and parking policies will be established by Landlord, and Tenant
agrees to adhere to said policies. UPON A COMPLAINT BY TENANT AND OTHER TENANTS OF THE BUILDING AND AT ANY OTHER TIME, Landlord reserves the right to implement and institute new parking policies as they are determined to benefit overall Building or
Phase operations. Tenant further agrees that its employees will not park in the visitor parking areas at any time. 
 7. If
Tenant desires signal, communication, alarm or other utility or service connection installed or changed, the same shall be made at the expense of Tenant, with approval and under direction of Landlord, Landlord’s Managing Agent or
Landlord’s contractors, it being understood and agreed that (a) no audible alarm shall be installed unless specifically approved in writing by Landlord prior to installation; and (b) only Tenant shall be obligated to respond to such
signal, communication, alarm or other utility or service connection, and none of Landlord, Landlord’s Managing Agent or other employee, agent or contractor of Landlord shall, under any circumstances have any obligation to Tenant or others to
respond to such alarm or be liable to Tenant or any party claiming by or through Tenant for any failure to do so. Any installations, and the boring or cutting for wires, shall be made at the sole cost and expense of Tenant and under control and
direction of Landlord. Landlord retains in all cases the right to require (x) the installation and use of such electrical-protecting devices that prevents the transmission of excessive current or electricity into or transmission of excessive
current or electricity into or through the Building (y) the changing of wires and of their installation and arrangement underground or otherwise as Landlord may direct, and (z) compliance on the part of all using or seeking access to such
wires with such rules as Landlord may establish relating thereto. All such wires used by Tenant must be clearly tagged at the distribution boards and junction box and elsewhere in the Building, with (h) the number of the Premises to which said
wires lead, (i) the purpose for which said wires are used and (j) the name of the company operating same. 

  
 B-1

 Tenant agrees to instruct all approved communication, and computer and other cabling
installers to attach cable in wire hangers from the deck or in any designated building floor or ceiling system cable location. Tenant will not allow installers to lay any cabling on top of the suspended layer ceiling system. 

8. Tenant shall give Landlord prompt notice of all accidents to or defects in air conditioning equipment, plumbing, electrical facilities
or any part of appurtenances of the Premises; provided nothing herein shall operate to modify Tenant’s obligations pursuant to subparagraph 6(a) of this Lease. 
 9. Tenant assumes full responsibility for protecting its space from theft, robbery, and pilferage, which includes keeping doors locked and other means of entry to the space closed and secured. Landlord
shall be in no way responsible to Tenant, its agents, employees, licensees, contractors or invitees for any loss of property from the Premises or public areas or for any damages to any property thereon from any cause whatsoever. 

10. Tenant shall not install or operate machinery or any mechanical devices of a nature not directly related to Tenant’s ordinary
use of the Premises without the prior written permission of the Landlord. Tenant shall not place in or move about the Premises any safe or other heavy article that, in Landlord’s reasonable opinion may damage the Premises (including the slab)
or overload the floor of the Premises, shall not mark on or drive nails, screw or drill into the partitions, woodwork or plaster (except as may be incidental to the hanging of wall decorations) and shall not in any way deface the Premises or any
part thereof. 
 11. No person or contractor not employed by Landlord shall be used to perform window washing, decorating,
repair or other work in the leased Premises without the express written consent of Landlord. 
 12. The directories of the
Building shall be used exclusively for the display of the name and location only of the tenants of the Building, including Tenant, and will be provided at the expense of Landlord. Any additional names requested by Tenant to be displayed in the
directories must be approved by Landlord and, if approved, will be provided at the sole expense of Tenant. 
 13. Tenant shall
not and shall ensure that its agents, servants, employees, licensees, contractors or invitees shall not: 
 (a)
enter into or upon the roof of the Building or any storage, electrical or telephone closet, or heating, ventilation, air conditioning, mechanical or elevator machinery housing areas; 

(b) use any additional method of heating or air conditioning the Premises, including, without limitation, space heaters of
any kind or nature; 
 (c) sweep or throw any dirt or other substance into ANY passageway, sidewalk or parking
area; 
 (d) bring in or keep in or about the Premises any firearms, vehicles, bicycles, motorcycles or animals
of any kind except service animals; 
 (e) deposit any trash, refuse or other substance of any kind within or out
of the Building, except in the refuse containers provided therefor; 
 (f) permit the operation any device that
may produce an odor, cause music, vibrations of air waves to be heard or felt outside the Premises, or that may emit electrical waves that shall impair radio, television or any other form of communication system; or 

(g) permit the carrying of a lighted cigar, cigarette, pipe or any other lighted smoking equipment or permit smoking of
cigarettes, cigars or pipes (i) in the common areas of the Building, including, without limitation, restrooms, except common areas that have been designated by Landlord in writing as smoking areas; or (ii) within ten (10) yards of any
door leading into the Building or any building comprising a part thereof. 
 14. Tenant will not install any radio or television
antennas or receptor dish or any device on the roof or grounds without the prior written approval of Landlord. Tenant understands that rentals are charged for roof space in the event any roof installation is approved in writing by Landlord. Landlord
reserves the right to require removal of any approved installed device in the event it is necessary to do so in Landlord’s opinion. 
 15. No sign, light, name placard, poster advertisement or notice visible from the exterior of any demised premises, shall be placed, inscribed, painted or affixed by Tenant on any part of the Building
without the prior written approval of Landlord. All signs or letterings on doors, or otherwise, approved by Landlord shall be inscribed, painted or affixed at the sole cost and expense of Tenant, by a person approved by Landlord. 

  
 B-2

 16. The toilet rooms, toilet, urinals, wash bowls and water apparatus shall not be used for
any purpose other than those for which they were constructed or installed, and no sweeping, rubbish, chemicals or other unsuitable substances shall be thrown or placed therein. Tenant shall bear the expense of repairing and cleaning up any breakage,
stoppage or damage resulting from violation(s) of this rule by Tenant or its agents, servants, employees, invitees, licensees or visitors. 
 17. Tenant must have Landlord’s prior written consent before using the name of the Building and/or pictures of the Building in advertising or other publicity. 

18. Tenant shall not make any room-to-room canvass to solicit business from other tenants in the Project, and shall not exhibit, sell or
offer to sell, use, rent or exchange in or from the Premises unless ordinarily embraced within Tenant’s use of the Premises specified herein. 
 19. Tenant shall not do any cooking in the Premises, except that Tenant may install a microwave oven and coffee makers for the use of its employees in the Premises. Under no circumstances shall Tenant
install or use any hot plates. 
 20. No portion of the Premises or any other part of the Building shall at any time be used or
occupied as sleeping or lodging quarters. 
 21. Landlord has the right to enact trash removal and trash recycling rules and
regulations as necessary to control trash removal costs or as required by the laws of the State of Minnesota and/or the United States of America. Tenant agrees to adhere to such trash removal regulations and to any and all modifications thereof
issued by Landlord from time to time. 
 22. Tenant will refer all contractors, contractors’ representatives and
installation technicians rendering any service to Tenant to Landlord’s Managing Agent for supervision, approval and control before performance of any contractual service. This provision shall apply to any work performed in the Building
including installations of telephones, telegraph equipment, electrical devices and attachments and installations of any nature affecting floors, walls, woodwork, trim, windows, ceilings, equipment or any other physical portion of the Building.

 23. Tenant shall not permit picketing or other union activity involving its employees in the Building except in those
locations and subject to time and other limitations as to which Landlord may give prior written consent. 
 24. Tenant shall not
conduct, or permit to be conducted on or from the Premises, any auction of Tenant’s personal property, any liquidation sale, any going-out-of-business sale or other similar activity. 

25. Landlord reserves the right to rescind, make reasonable amendments, modifications and additions to the rules and regulations
heretofore set forth, and to make additional reasonable rules and regulations, as in Landlord’s sole judgment may from time to time be needed for the safety, care, cleanliness and preservation of good order of the Building. Landlord shall not
be responsible for any violation of the foregoing rules and regulations by other tenants of the Building and shall have no obligation to enforce the same against other tenants. 

  
 B-3

 EXHIBIT C 
 Intentionally Omitted 

  
 C-1

 EXHIBIT D 
 PLYMOUTH BUSINESS CENTER 
 SIGNAGE CRITERIA 

FRONT ENTRANCE DOOR 
 White Vinyl Applied Letters Only 
 “2 Maximum Height 

Helvetica Letters 

Two or Three Lines Only 
 Logos, Script, or Color Variations 
 REAR OVERHEAD DOOR 

Black Vinyl Applied Letters Only 
 6” Maximum Height 
 Helvetica Letters 

One or Two Lines Only 
 No Logos, Script, or Color Variations 
 REAR ENTRANCE/HOLLOW METAL DOOR

 Black Vinyl Applied Letters Only 
 2# Maximum Height 
 Helvetica Letters 

Two or Three Lines Only 
 No Logos, Script, or Color Variations 
 FRONT OVERHEAD SIGN 

Freeway Exposure (mounted below wallpack lighting) 
 4’ x 8’ Black Acrylic Background Panel 
 White or Gray Copy Only

 Logo Reproduction Permitted 
 Non-Freeway Exposure (mounted adjacent to entrance door) 
 2.5’ x
3.5’ Black Acrylic Background Panel 
 White or Gray copy Only 

Logo Reproduction Permitted 
  

 
 NOTE: 

Signage must meet Landlord approval prior to installation. 
 Signage contractor must obtain permit from City if required. 

  
 D-1

 EXHIBIT E 
 MOVE-OUT STANDARDS 
 Not later than the Restoration Date (as defined in the Lease), Tenant
shall deliver the Premises to Landlord in the same condition as they were upon delivery of possession thereto under this Lease, reasonable wear and tear excepted, and shall deliver all keys to Landlord. Before delivery of the Premises to Landlord,
Tenant shall remove all of its personal property and all alterations, additions, installations, improvements, partitions, Cabling and trade fixtures, all as and to the extent provided in Paragraph 7 of this Lease. If Tenant fails to remove its
personal property and fixtures upon the expiration of this Lease, the same shall be deemed abandoned and shall become the property of the Landlord. 
 The Tenant shall, on the Restoration Date, place the Premises in a condition that shall include, but is not limited to, the following: 

 

					
	1.	  	Lights:	  	Office and warehouse lights will be fully operational with all bulbs functioning.
			
	2.	  	Dock Levelers & Roll Up Doors:	  	All dock levelers and roll-up doors will be in good working condition.
			
	3.	  	Dock Seals:	  	All dock seals will be free of tears and any broken backboards repaired.
			
	4.	  	Warehouse Floor:	  	The warehouse floor will swept with no racking bolts or other protrusions left in floor. Cracks will be repaired with an epoxy or polymer.
			
	5.	  	Equipment & Wiring:	  	Unless otherwise specified by Landlord in writing, all equipment and wiring shall be removed and the Premises returned to original condition, including, without limitation, removal
of air lines, junction boxes, conduit, etc.).
			
	6.	  	Walls:	  	Sheetrock (drywall) damage should be patched and fire-taped so that there are no holes in either office or warehouse.
			
	7.	  	Roof:	  	Any tenant-installed equipment must be removed and roof penetrations properly repaired by a licensed roofing contractor selected or approved by Landlord. Active leaks must be fixed
and latest Landlord maintenance and repairs recommendation must have been followed.
			
	8.	  	Signs:	  	All exterior signs must be removed and holes patched and paint touched up as necessary. All window signs should likewise be removed.
			
	9.	  	Heating & Air Conditioning System:	  	A written report from a licensed HVAC contractor within the last three months stating that all evaporative coolers within the Premises are operational and safe and in good and safe
operating condition.
			
	10.	  	Overall Cleanliness:	  	Clean windows, sanitize bathroom(s), vacuum carpet, and remove any and all debris from office and warehouse. Remove all pallets and debris from exterior premises.
			
	11.	  	Upon Completion:	  	Contact Landlord’s property manager to coordinate date of turning off power, turning in keys, and obtaining final Landlord inspection of Premises.

 Nothing in this Exhibit E obligates Tenant to remove the “Improvements”, as Paragraph 31 of this Lease
defines that term, from the Premises. 

  
 E-1

 EXHIBIT F 
 EXISTING IMPROVEMENTS 
 (See attached) 

  
 F-1

 

 

  
 F-2

															
	 Asset Number
	  	 Functional Area
	  	 Equipment Number
	  	 Description
	  	 Manufacturer
	  	 Model
	  	 Serial Number
	  	Room
	 33092
	  		  	E1977	  	4 Channel In-Line Degasser	  		  		  		  	129
	 NA
	  	Utility	  	E1925	  	Air Compressor, Backup - 49 scfm @ 90 psi	  	Ingersoll-Rand	  	OL15E15	  	30T973670	  	140
	 NA
	  	Utility	  	E2219	  	Air Compressor, Primary - 44 scfm @ 100 psi	  	Powerex	  	SET 150 740	  	) 6/5/2003 - 2232182-	  	140
	 NA
	  	Utility	  	E1928	  	Air Handling Unit #1	  	McQuay	  	CAH014FDAC	  	F80U010900562	  	157
	 IMA
	  	Utility	  	E1926	  	Air Handling Unit #2	  	McQuay	  	CAH014FDAC	  	F80U010900561	  	157
	 NA
	  	Utility	  	E2201	  	Air Handling Unit, Boiler Room	  	McQuay	  	CAH012FDAC	  	FBOU021100007	  	140
	 NA
	  	Cell Culture	  	NA	  	Analyzer, Biochemistry	  	Nova Biomedical	  	ova 100 Plus Bioprofile 3829	  	T34A06040	  	129
	 33012
	  	Cell Culture	  	E1307	  	Analyzer, Biochemistry, Dual Channel	  	YSI	  	2700 Select	  	95B29414	  	129
	 33068
	  	Cell Culture	  	E1879	  	Analyzer, Biochemistry, Dual Channel	  	YSI	  	2700 Select	  	01J0718AA	  	129
	 NA
	  	Cell Culture	  	E1308	  	Analyzer, Biochemistry, Dual Channel	  	YSI	  	2700 Select	  	96M0363AA	  	157
	 NA
	  	Cell Culture	  	NA	  	Analyzer, Biochemistry, Dual Channel	  	YSI	  	2700 Select	  	05M0118	  	131
	 33009
	  	Cell Culture	  	El 243	  	Analyzer, Blood Gas	  	ABL	  	ABL-5	  	142R0121N05	  	131
	 33171
	  	Cell Culture	  	NA	  	Analyzer, Blood Gas	  	ABL	  	ABL-5	  	142R0472N001	  	129
	 33150
	  	Cell Culture	  	NA	  	Analyzer, Chemistry	  	Drtho Clinical Diagnostics	  	tros DT60 II Chemistry System	  	60034165	  	157
	 NA
	  	Cell Culture	  	NA	  	Analyzer, Chemistry, Module (goes with 33150)	  	Ortho Clinical Diagnostics	  	DTSC II Module	  	62022192	  	157
	 33204
	  	Analytical	  	NA	  	Analyzer, iCE280 With PrinCE	  	Convergent Biosciences	  	iCE280 Analyzer	  	1122	  	105
	 NA
	  	Clean & Wash	  	E1880	  	Autoclave	  	Getinge	  	GE6912AR-1	  	5100572-010-01	  	140
	 33109
	  	Utility	  	NA	  	Automatic External Defibrillator	  	Medtronic	  	.ifePack 500 3011790-00011:	  	14202709	  	119
	 33218
	  	Cell Culture	  	95-AS-1200	  	Autosampler	  	Innovatis	  	MS20	  	10001511	  	129
	 NA
	  	Cell Culture	  	E2350	  	Bag Cart	  	Stedim	  	NA	  	NA	  	131
	 NA
	  	Cell Culture	  	E2439	  	Bag Cart	  	Stedim	  	NA	  	NA	  	131
	 NA
	  	Cell Culture	  	NA	  	Bag Cart	  	Stedim	  	NA	  	NA	  	131
	 NA
	  	Cell Culture	  	NA	  	Bag Cart	  	Stedim	  	NA	  	NA	  	131
	 33069
	  	Purification	  	E1913	  	Balance	  	Sartorius	  	LP2200	  	13308632	  	129
	 33070
	  	Purification	  	E1914	  	Balance	  	Sartorius	  	LP2200	  		  	129
	 33071
	  	Purification	  	E1915	  	Balance	  	Sartorius	  	LP2200	  	13406888	  	129
	 33086
	  	Purification	  	E1897	  	Balance	  	Mettler-Atoledo	  	AX205	  	112051104	  	129
	 33103
	  	Cell Culture	  	E2032	  	Balance	  	Sartorius	  	LP2200	  	13804679	  	129
	 33104
	  	Cell Culture	  	E2033	  	Balance	  	Sartorius	  	LP2200	  	13804677	  	129
	 33105
	  	Cell Culture	  	E2034	  	Balance	  	Sartorius	  	LP2200	  	13804680	  	129
	 33106
	  	Cell Culture	  	E2035	  	Balance	  	Sartorius	  	LP2200	  	13804676	  	130
	 33107
	  	Cell Culture	  	E2090	  	Balance	  	Sartorius	  	LP2200	  	14405037	  	131
	 33115
	  	Purification	  	E2094	  	Balance	  	Sartorius	  	LP2200	  	14007266	  	129
	 33130
	  	Purification	  	E2047	  	Balance	  	Sartorius	  	LP2200	  	14106678	  	129
	 33131
	  	Purification	  	E2048	  	Balance	  	Sartorius	  	LP2200	  		  	129
	 33132
	  	Purification	  	E2049	  	Balance	  	Sartorius	  	LP2200	  	14405038	  	129

  
 F-3

															
	 Asset Number
	  	 Functional Area
	  	 Equipment Number
	  	 Description
	  	 Manufacturer
	  	 Model
	  	 Serial Number
	  	Room
	 33133
	  	Purification	  	E2050	  	Balance	  	Sartorius	  	LP2200	  	14306850	  	129
	 33157
	  	Purification	  	E2475	  	Balance	  	Sartorius	  	LE2202S	  	17210443	  	129
	 NA
	  	Cell Culture	  	95-SC-1201	  	Balance	  	Sartorius	  	LP2200	  	15202516	  	130
	 33065
	  	Cell Culture	  	E1827	  	Balance (For Viral Filtration)	  	Sartorius	  	BP 16000-S	  	12511303	  	129
	 30516
	  	Purification	  	E1910	  	Bath, Circulating Water	  	Pharmacia Biotech - The	  	MultiTemp III - 56-1165-33	  	1200103454019	  	157
	 33015
	  	Metrology	  	E1305	  	Bath, Circulating Water	  		  	1130-2	  	613990	  	129
	 33145
	  	Metrology	  	E2157	  	Bath, Circulating Water	  	VWR	  	1137-2P	  	G23148	  	136
	 33146
	  	Metrology	  	E2158	  	Bath, Circulating Water	  	VWR	  	1137-2P	  	G23159	  	136
	 33021
	  	Cell Culture	  	E0715	  	Bioreactor System, 150 L	  	ABEC	  	150L	  	8870-1	  	131
	 33179
	  	Cell Culture	  	E2377	  	Bioreactor System, 150 L	  	ITT Pure-Flo	  	P210CP	  	NA	  	131
	 33180
	  	Cell Culture	  	E2386	  	Bioreactor System, 150 L	  	ITT Pure-Flo	  	P310CP	  	NA	  	131
	 33061
	  	Cell Culture	  	E1767	  	Bioreactor System, Dual 2L	  	Braun	  	Biostat MD2 Dual	  	(Various in System)	  	129
	 33122
	  	Cell Culture	  	E2031	  	Bioreactor System, Dual 2L	  	Braun	  	Biostat (BDCU)	  	(Various in System)	  	129
	 33185
	  	Cell Culture	  	E2504	  	Bioreactor System, Dual 2L	  	Braun	  	Biostat (BDCU)	  	(Various in System)	  	131
	 33186
	  	Cell Culture	  	E2505	  	Bioreactor System, Dual 2L	  	Braun	  	Biostat (BDCU)	  	(Various in System)	  	131
	 33162
	  	Cell Culture	  	E2285	  	Bioreactor System, Quad 2L	  	Braun	  	Biostat (BDCU)	  	(Various in System)	  	131
	 33263
	  	Cell Culture	  	95-BRX-1200	  	Bioreactor System, Quad 2L	  	Sartorius	  	Biostat (BDCU)	  	(Various in System)	  	131
	 33167
	  	Cell Culture	  	E2407	  	Bioreactor System, Wave	  	Wave	  	System 20P	  	0110.0304.2050P	  	129
	 NA
	  	Cell Culture	  	E2404	  	Bioreactor System, Wave	  	Wave	  	System 20P	  	0111.0304.2050P	  	129
	 NA
	  	Utility	  	E0082	  	Biosafety Cabinet	  	Nuaire	  	NU-425-600	  	21168VU	  	129
	 NA
	  	Utility	  	E1929	  	Iler, Aerco (Hydronic - 1,000,000 BTU/Hr, 90% ef	  	Aerco	  	N/A	  	G-01-0776	  	141
	 NA
	  	Utility	  	E1929	  	iler, Aerco (Hydronic - 1,000,000 BTU/Hr, 90% ef	  	Aerco	  	N/A	  	G-01-0777	  	141
	 NA
	  	Utility	  	E1918	  	Boiler, High Pressure (Process) - 30HP	  	Fulton	  	ICS 30	  	89438	  	141
	 33194
	  	Analytical	  	NA	  	busLAC/E Box	  	Waters	  	LAC/E32	  	B06L32055W	  	105
	 33195
	  	Analytical	  	NA	  	busLAC/E Box	  	Waters	  	LAC/E32	  	M05L32456W	  	105
	 33196
	  	Analytical	  	NA	  	busLAC/E Box	  	Waters	  	LAC/E32	  	M05L32464W	  	105
	 33197
	  	Analytical	  	NA	  	busLAC/E Box	  	Waters	  	LAC/E32	  	B06L32120W	  	105
	 33005
	  	Metrology	  	E1150	  	Calibrator, Low Temperature Dry Well With Inserts	  	Hart Scientific	  	9105	  	94279	  	136
	 33143
	  	Metrology	  	E2138	  	Calibrators, Dry-Well	  	Hart Scientific	  	9103	  	A33466	  	136
	 NA
	  	Metrology	  	E1658	  	Calibrators, Dry-Well	  	Hart Scientific	  	9103	  	98052	  	136
	 NA
	  	Metrology	  	E2139	  	Calibrators, Dry-Well	  	Hart Scientific	  	9103	  	A33464	  	136
	 33075
	  	Cell Culture	  	E1883	  	Cell Counting System, Cedex	  	Innovatis	  	(first model)	  	G007D1089	  	129
	 33175
	  	Cell Culture	  	E2449	  	Cell Counting System, ViCell	  	Beckman Coulter	  	ViCell XR	  	0AJ24118	  	129
	 33173
	  	Cell Culture	  	E2340	  	Centrifuge	  	Alpha Laval	  	LAPX404SGP-31C	  	4126998	  	131
	 33237
	  	dia & Buffer Preparat	  	95-CEN-1200	  	Centrifuge	  	Beckman Coulter	  	Avanti J-26 XPI	  	1053894	  	129
	 NA
	  	Analytical	  	NA	  	Centrifuge, LCC Carousel	  	Roche	  	LCC Centrifuge 2.0	  	40511846	  	157

  
 F-4

															
	 Asset Number
	  	 Functional Area
	  	 Equipment Number
	  	 Description
	  	 Manufacturer
	  	 Model
	  	 Serial Number
	  	Room
	 33231
	  	Analytical	  	95-AN-8300	  	Characterization System, Protein	  	Beckman Coulter	  	PA800	  	3063329	  	105
	 32984
	  	Utility	  	E0144	  	Chart Recorder	  	Honeywell	  	DR45	  	9218862396011	  	137
	 33006
	  	Utility	  	E1192	  	Chart Recorder	  	Honeywell	  	DR45	  	9625Y6260902000002	  	157
	 NA
	  	Utility	  	E0710	  	Chart Recorder	  	Honeywell	  	DR45	  	93271236810008	  	154
	 NA
	  	Utility	  	E1057	  	Chart Recorder	  	Honeywell	  	DR45	  	9538Y522698300001	  	157
	 33110
	  	Utility	  	E1917	  	Chiller, 3850 House - 50 ton capacity	  	McQuay	  	AGZ050A527-ER10	  	STNU011000083	  	Parking
Lot (E
	 NA
	  	Utility	  	E1919	  	Chiller, 3850 Process - 7.5 ton capacity	  	Arctic Chill	  	MACVPV0075S4	  	6056101	  	Parking
Lot (E
	 NA
	  	Utility	  	E2202	  	Chiller, Boiler Room - 16 ton capacity	  	McQuay	  	ACZ016AC27-ER10	  	STNU0Z1100097	  	Parking
Lot (E
	 33022
	  	Purification	  	E1573	  	Chromatography System, Development	  	are (Amersham Pharmac	  	AKTA Explorer 100	  	001028	  	157
	 33046
	  	Purification	  	E1659	  	Chromatography System, Development	  	:are (Amersham Pharmac	  	AKTA Explorer 100	  	001821	  	129
	 33102
	  	Purification	  	E1990	  	Chromatography System, Development	  	are (Amersham Pharmac	  	AKTA Purifier 100	  	01041822	  	129
	 33163
	  	Purification	  	E2269	  	Chromatography System, Development	  	Ithcare (Amersham Biosc	  	AKTA Pilot	  	01083186	  	157
	 33166
	  	Purification	  	E2473	  	Chromatography System, Development	  	Ithcare (Amersham Biosc	  	AKTA Purifier 100	  	01133947	  	129
	 33178
	  	Purification	  	E2501	  	Chromatography System, Development	  	Ithcare (Amersham Biosc	  	AKTA Explorer 100	  	01181121	  	129
	 33184
	  	Purification	  	E2474	  	Chromatography System, Development	  	Ithcare (Amersham Biosc	  	AKTA Explorer 100	  	01136604	  	129
	 33202
	  	Purification	  	NA	  	Chromatography System, Development	  	GE Healthcare	  	AKTA Explorer 100	  	1301175	  	129
	 33275
	  	Purification	  	95-XX-5000	  	Chromatography System, Development	  	GE Healthcare	  	AKTA Explorer 100	  	1438206	  	129
	 33037
	  	Purification	  	E1574	  	Chromatography System, Pilot	  	Millipore	  	K-Prime 40-1	  	NA	  	169
	 33200
	  	Purification	  	NA	  	Chromatography System, Pilot	  	are (Amersham Pharmac	  	AKTA Pilot	  	1281693	  	129
	 33120
	  	Analytical	  	E2008	  	CIEF System	  	Convergent Biosciences	  		  		  	?
	 33088
	  	Utility	  	E1920	  	CIP Skid	  	Cotter Corporation	  	SK-006	  	NA	  	141
	 33090
	  	Utility	  	E1973	  	Clean Steam System - 550 Ibs/hr @ 50 psi	  	Finn-Aqua	  	Finn-Aqua 300G	  	39252	  	141
	 NA
	  	Utility	  	E1878	  	Cold Room 130	  	Thermo-Kool	  	TK-4878-F-L	  	38680 EJS	  	129
	 33113
	  	Utility	  	NA	  	Compressed Gases System	  	Genmab	  	NA	  	NA	  	146
	 33268
	  	Analytical	  	95-XX-8300	  	Concentrator, Speed Vac	  	Savant	  	SPD131P-120	  	5PD131D-9K450108-ly	  	129
	 NA
	  	Analytical	  	95-XX-8300	  	Concentrator, Speed Vac - Refrigerated Vapor Tra^	  	Savant	  	RUT4104-120	  	120	  	129
	 NA
	  	Analytical	  	95-XX-8300	  	Concentrator, Speed Vac - Vacuum Pump	  	Savant	  	OFP400-115	  	02F260184-1B	  	129
	 NA
	  	Utility	  	E1852	  	Cond/Evap Units	  	Heatcraft Inc	  	MOZ055M64CF	  	39(unit#l) T01K0089	  	Cold
Room
169
	 NA
	  	Utility	  	E1853	  	Cond/Evap Units	  	Heatcraft Inc	  	MOZ045M64CF	  	T01K00830	  	158
	 33074
	  		  	E1863	  	Conductivity Meter For Orion Electrode	  		  		  		  	129
	 NA
	  	Analytical	  	E2513	  	Conductivity Meter For Orion Electrode	  	lermo Electron Corporate	  	Orion 3 Star	  	008500	  	105
	 33192
	  	Analytical	  	E2508	  	Densitometer, GS800 Calibrated	  	Bio-Rad	  	PowerLook 2100XL	  	H9D00507A0041	  	157
	 33201
	  	Analytical	  	NA	  	Detector, Charge Aerosol	  	ESA Biosciences	  	Corona Plus 70-6967	  	CP-0150	  	129
	 33114
	  	Utility	  	NA	  	Electric Truck For 3850 Warehouse	  	Big Joe	  	1518-T08	  	370556	  	157
	 NA
	  	Analytical	  	E1855	  	Electrophoresis Power Supply	  	lermo Electron Corporation	  	EC105	  	105ECA-1K471209-1A	  	129
	 NA
	  	Analytical	  	E1856	  	Electrophoresis Power Supply	  	lermo Electron Corporation	  	EC105	  	105ECA-1K471217-1A	  	129

  
 F-5

															
	 Asset Number
	 	 Functional Area
	 	 Equipment Number
	 	 Description
	 	 Manufacturer
	 	 Model
	 	 Serial Number
	 	Room
	 NA
	 	Analytical	 	E1911	 	Electrophoresis Power Supply	 	nersham Pharmacia Biote	 	EPS 3501 XL	 	01034575	 	129
	 NA
	 	Utility	 	E2271	 	Exhaust Fan	 	Penn Ventilation Co,	 	DX08B	 	N/A	 	Roof
	 NA
	 	Utility	 	E2272	 	Exhaust Fan	 	Penn Ventilation Co.	 	DX08B	 	N/A	 	Roof
	 NA
	 	Utility	 	E2273	 	Exhaust Fan	 	Penn Ventilation Co.	 	DX36B	 	N/A	 	Roof
	 NA
	 	Utility	 	E2274	 	Exhaust Fan	 	Penn Ventilation Co.	 	DX08B	 	N/A	 	Roof
	 NA
	 	Utility	 	E2275	 	Exhaust Fan	 	Penn Ventilation Co.	 	DX08B	 	N/A	 	Roof
	 NA
	 	Utility	 	E2276	 	Exhaust Fan	 	Penn Ventilation Co.	 	DX08B	 	N/A	 	Roof
	 NA
	 	Utility	 	E2277	 	Exhaust Fan	 	Penn Ventilation Co.	 	DX1B	 	N/A	 	Roof
	 NA
	 	Utility	 	E2278	 	Exhaust Fan	 	Penn Ventilation Co.	 	DC08B	 	N/A	 	Roof
	 NA
	 	Utility	 	E2279	 	Exhaust Fan	 	Penn Ventilation Co.	 	DX08B	 	N/A	 	Roof
	 NA
	 	Utility	 	E2280	 	Exhaust Fan	 	Penn Ventilation Co.	 	DX08B	 	N/A	 	Roof
	 NA
	 	Utility	 	E2281	 	Exhaust Fan	 	Penn Ventilation Co.	 	DX08B	 	N/A	 	Roof
	 NA
	 	Metroloqy	 	NA	 	Field Communicator, Hart	 	Sae-Stahl	 	375	 	11008890	 	136
	 33270
	 	Cell Culture	 	95-TX-1200	 	Filter Testing Station	 	FilterTec	 	CP-120	 	NA	 	129
	 NA
	 	Cell Culture	 	E0310	 	Filter Testing Station	 	Sartorius	 	arto Check II D3400 - SM1621	 	4203417	 	129
	 33187
	 	Analytical	 	E2507	 	Fluorescence Detector	 	Waters	 	W2475	 		 	105
	 NA
	 	Utility	 	NA	 	Freezer, Chest	 	Frlqidaire Commercial	 	FCCS201FWO	 	WB63328822	 	157
	 NA
	 	Cell Culture	 	95-CSU-1200	 	Freezer, Cryogenic	 	Custom Biogenics System	 	V-1500	 	B041116C-1	 	137
	 33025
	 	Utility	 	E1377	 	Freezer, Upriqht	 	Forma Scientific	 	916	 	85171-635	 	135
	 33027
	 	Utility	 	E1389	 	Freezer, Upriqht	 	Forma Scientific	 	916	 	85134-665	 	129
	 33028
	 	Utility	 	E1390	 	Freezer, Upright	 	Forma Scientific	 	916	 	85173-645	 	137
	 33045
	 	Utility	 	E1804	 	Freezer, Upright	 	Forma Scientific	 	916	 	20771-981	 	129
	 33176
	 	Utility	 	E2463	 	Freezer, Upriqht	 	Revco	 	ULT 1340-9-A37	 	YIIO-273885-YO	 	135
	 33177
	 	Utility	 	E2464	 	Freezer, Upriqht	 	Revco	 	ULT 1386-9-A37	 	YI20-273926-YO	 	135
	 33198
	 	Utility	 	E2512	 	Freezer, Upriqht	 	Thermo Scientific	 	904	 	810131-448	 	137
	 NA
	 	Utility	 	E0308	 	Freezer, Upriqht	 	ter Scientific Products/Re	 	U2186 D-U-A	 	WZ 24604-3	 	157
	 NA
	 	Utility	 	E0309	 	Freezer, Upright	 	ter Scientific Products/Re	 	U2186 D-U-A	 	WZ 2Y604-1E	 	171
	 NA
	 	Utility	 	E0365	 	Freezer, Upriqht	 	VWR	 	D8517-U-0-D	 	PX64104H	 	137
	 NA
	 	Cell Culture	 	E0960	 	Freezer, Upriqht	 	Forma Scientific	 	916	 	87054-238	 	
	 NA
	 	Utility	 	E1900	 	Freezer, Upright	 	Revco Technologies	 	ULT2140-5-D35	 	007M-568242-OM	 	154
	 NA
	 	Metrology	 	E0681	 	Fume Hood	 	Labconco	 	48800	 	234542	 	136
	 NA
	 	Utility	 	E1854	 	Fume Hood	 	/aunee Scientific Corpora	 	HOSK5448B00	 	120617	 	129
	 NA
	 	Utility	 	E2396	 	Fume Hood	 	/aunee Scientific Corpora	 	HOSKSYV8	 	1934	 	105
	 NA
	 	Metrology	 	NA	 	Gas Mixer, Environics	 	Environics	 	Series 4000	 	3266	 	136
	 NA
	 	Utility	 	E1924	 	Generator, Backup #1 - 100KW	 	Cummins Genset	 	WSG1068IT-6005-A	 	01-08-007669	 	144
	 NA
	 	Utility	 	E2307	 	Generator, Backup #2 - 100KW	 	Cummins Genset	 	WSG1068IT-6005-A	 	1030549315	 	147

  
 F-6

															
	 Asset Number
	  	 Functional Area
	  	 Equipment Number
	  	 Description
	  	 Manufacturer
	  	 Model
	  	 Serial Number
	  	Room
	 NA
	  	Analytical	  	E1709	  	HPLC Alliance System (with E1708 and E1707)	  	Waters	  	A/AT270886 [W2690 (pump)l	  	D00SM7 052M	  	105
	 NA
	  	Analytical	  	E1712	  	HPLC Alliance System (with E1711 and E1710)	  	Waters	  	WAT270886 [W2690 (pump)l	  	D00SM7 038M	  	105
	 33076
	  	Analytical	  	E1890	  	HPLC Alliance System (with E1889 and E1888)	  	Waters	  	WAT270008 [W2690 (pump)’	  	M01SM4 593M	  	105
	 33140
	  	Analytical	  	E2101	  	HPLC Alliance System (with E2102 and E2103)	  	Waters	  	A/AT270008 TW2690 (pump)’	  	K02SM4 318M	  	105
	 33141
	  	Analytical	  	E2131	  	HPLC Alliance System (with E2132 and E1706)	  	Waters	  	WAT270008 [W2690 (pump)l	  	M02SM4 919M	  	105
	 NA
	  	Analytical	  	E1705	  	HPLC Alliance System (with E2397 and E2133)	  	Waters	  	A/AT270886 [W2690 (pump)]	  	D00SM7 045M	  	105
	 NA
	  	Analytical	  	E2402	  	HPLC Alliance System (with E2401 and E2400)	  	Waters	  	WAT270008 [W2690 (pump)]	  	C04SM4 250M	  	105
	 NA
	  	Analytical	  	E2399	  	HPLC Alliance System (with E2507 and E2398)	  	Waters	  	WAT270008 [W2690 (pump)’	  	C045SM4 282M	  	105
	 NA
	  	Analytical	  	E1706	  	HPLC Alliance System Column Heater/Cooler	  	Waters	  	WAT270852	  	D00SMH 355M	  	105
	 NA
	  	Analytical	  	E1707	  	HPLC Alliance System Column Heater/Cooler	  	Waters	  	WAT270852	  	D00SMH 356M	  	105
	 NA
	  	Analytical	  	E1710	  	HPLC Alliance System Column Heater/Cooler	  	Waters	  	WAT270852	  	DOOSMH 317M	  	105
	 NA
	  	Analytical	  	E1888	  	HPLC Alliance System Column Heater/Cooler	  	Waters	  	WAT270852	  	M01SMH 022M	  	105
	 NA
	  	Analytical	  	E2103	  	HPLC Alliance System Column Heater/Cooler	  	Waters	  	WAT270852	  	J02SMH 677M	  	105
	 NA
	  	Analytical	  	E2133	  	HPLC Alliance System Column Heater/Cooler	  	Waters	  	186001863	  	L02SMH 054M	  	105
	 NA
	  	Analytical	  	E2398	  	HPLC Alliance System Column Heater/Cooler	  	Waters	  	186001863	  	C04SMH 605M	  	105
	 NA
	  	Analytical	  	E2400	  	HPLC Alliance System Column Heater/Cooler	  	Waters	  	186001863	  	C04SMH 590M	  	105
	 NA
	  	Analytical	  	E1708	  	HPLC Alliance System Detector	  	Waters	  	T081110 [W2487 (UV detector)	  	D00487 383M	  	105
	 NA
	  	Analytical	  	E1711	  	HPLC Alliance System Detector	  	Waters	  	T081110 [W2487 (UV detector)	  	D00487.301M	  	105
	 NA
	  	Analytical	  	E1716	  	HPLC Alliance System Detector	  	Waters	  	996 (PDA detector)]	  	MX4MM8071M	  	105
	 NA
	  	Analytical	  	E1889	  	HPLC Alliance System Detector	  	Waters	  	000869 [W2996 (PDA detector)	  	M01996 263M	  	105
	 NA
	  	Analytical	  	E2102	  	HPLC Alliance System Detector	  	Waters	  	000869 [W2996 (PDA detector)	  	J02296 718M	  	105
	 NA
	  	Analytical	  	E2132	  	HPLC Alliance System Detector	  	Waters	  	000869 [W2996 (PDA detector)	  	M02296 263M	  	105
	 NA
	  	Analytical	  	E2397	  	HPLC Alliance System Detector	  	Waters	  	T081110 TW2487 (UV detector)	  	C04487 916M	  	105
	 NA
	  	Analytical	  	E2401	  	HPLC Alliance System Detector	  	Waters	  	T081110 TW2487 (UV detector)	  	C04487.884M	  	105
	 NA
	  	Analytical	  	E2507	  	HPLC Alliance System Detector	  	Waters	  	V75 [W2475 (Fluorescence detector)	  	J05475.410M	  	105
	 33007
	  	Utility	  	E1213	  	Incubator	  	VWR	  	2020	  	500796	  	137
	 33066
	  	Utility	  	E1831	  	Incubator	  	VWR	  	2020	  	301201	  	137
	 NA
	  	Cell Culture	  	E1665	  	Incubator	  	Forma Scientific	  	3950	  	46030-57	  	157
	 NA
	  	Analytical	  	NA	  	Incubator	  	Thermo Scientific	  	120	  	1460081256851	  	157
	 33016
	  	Cell Culture	  	E1310	  	Incubator, C02	  	Forma Scinetific	  	3956	  	26229-2729	  	129
	 33054
	  	Cell Culture	  	E1689	  	Incubator, C02	  	Forma Scinetific	  	3956	  	64362-101	  	129
	 33164
	  	Cell Culture	  	E2394	  	Incubator, C02	  	Forma Scientific	  	3950	  	302895-981	  	129
	 NA
	  	Utility	  	E0892	  	Laminar Flow Hood	  	Nuaire	  	NU-301-636	  	63738	  	129
	 33014
	  		  	E0557	  	Leitz DM IL Basic Stand, Condenser AO.23	  		  		  		  	129
	 33181
	  	Analytical	  	E2469	  	Lightcycler	  	Roche	  	NA	  	1405748	  	157
	 33253
	  	Analytical	  	95-PCR-8300	  	LightCycler 480 Real Time PCR 96 Well System	  	Roche	  	480 II	  	25495	  	105

  
 F-7

															
	 Asset Number
	 	 Functional Area
	 	 Equipment Number
	 	 Description
	 	 Manufacturer
	 	 Model
	 	 Serial Number
	 	Room
	 33036
	 	Metrology	 	E1514	 	LowTemp Calibration Bath	 	Hart Scientific	 	7102	 	81015	 	136
	 33017
	 	Cell Culture	 	E1519	 	MF Skid	 	Genmab	 	NA	 	NA	 	131
	 33097
	 	Analytical	 	E1885	 	Mlcrocentrifuge	 	Eppendorf	 	5804	 	02213	 	129
	 NA
	 	Analytical	 	E2514	 	Microcentrifuge	 	Eppendorf	 	5804	 	0011696	 	129
	 NA
	 	Analytical	 	NA	 	Microcentrifuge	 	Galaxy	 	C12XX-220V	 	0501-0590	 	129
	 32834
	 	Analytical	 	NA	 	Microplate Reader, Spectramax	 	Molecular Devices	 	Spectra-Max 340 PC	 	LN02400	 	105
	 33087
	 	Analytical	 	E1909	 	Microplate Reader, Spectramax	 	Molecular Devices	 	Spectra-Max 340 PC	 	LN02053	 	105
	 NA
	 	Analytical	 	E2000	 	Microplate Reader, Thermomax	 	Molecular Devices	 	Thermomax	 	06379	 	105
	 NA
	 	Cell Culture	 	E1031	 	Microscope	 	Nikon	 	Labophot-2	 	15202516	 	129
	 NA
	 	Cell Culture	 	E1032	 	Microscope	 	Nikon	 	Labophot-2	 	461785	 	129
	 NA
	 	Cell Culture	 	E1304	 	Microscope	 	Lecia	 	DMIL090-131.001	 	520802	 	129
	 NA
	 	Cell Culture	 	NA	 	Microscope	 	Elica	 	410	 	19144-3	 	129
	 NA
	 	Analytical	 	NA	 	Mixer, Vortex	 	Bamstead/Thermolyne	 	37600 Mixer - Maxi Mix II M3	 	1254011193993	 	129
	 NA
	 	Analytical	 	NA	 	Mixer, Vortex	 	Barnstead/Thermolyne	 	37600 Mixer - Maxi Mix II Ml	 	1254011193859	 	129
	 NA
	 	Analytical	 	NA	 	Mixer, Vortex	 	Barnstead/Thermolyne	 	37600 Mixer - Maxi Mix II M3	 	1254011194005	 	129
	 NA
	 	Analytical	 	NA	 	Mixer, Vortex	 	Barnstead/Thermolyne	 	37600 Mixer - Maxi Mix II m:	 	1254050248241	 	129
	 NA
	 	Analytical	 	NA	 	Mixer, Vortex	 	Barnstead/Thermolyne	 	37600 Mixer - Maxi Mix II Ml	 	1254050248281	 	105
	 NA
	 	Analytical	 	NA	 	Mixer, Vortex	 	Barnstead/Thermolyne	 	37600 Mixer - Maxi Mix II Ml	 	1254021175312	 	105
	 NA
	 	Analytical	 	NA	 	Mixer, Vortex	 	Barnstead/Thermolyne	 	37600 Mixer - Maxi Mix II Ml	 	11254050245416	 	105
	 NA
	 	Analytical	 	NA	 	Mixer, Vortex	 	Bamstead/Thermolyne	 	37600 Mixer - Maxi Mix II Ml	 	1254050248269	 	105
	 NA
	 	Analytical	 	NA	 	Mixer, Vortex	 	Barnstead/Thermolyne	 	37600 Mixer - Maxi Mix II Ml	 	1254021175177	 	105
	 33151
	 	dia & Buffer Preparat	 	NA	 	Mixing Tank, 100 L	 	T&C Stainless	 	NA	 	TC5914	 	131
	 33174
	 	dia & Buffer Preparat	 	E2489	 	Mixing Tank, 100 L	 	T&C Stainless	 	NA	 	TC6198	 	131
	 NA
	 	dia & Buffer Preparat	 	NA	 	Mixing Tank, 100 L	 	T&C Stainless	 	NA	 	TC6015	 	131
	 33135
	 	dia & Buffer Preparat	 	NA	 	Mixing Tank, 200 L	 	T&C Stainless	 	NA	 	TC5741	 	131
	 33193
	 	dia & Buffer Preparat	 	NA	 	Mixing Tank, 200 L With Agitator	 	Hans Pedersen Group	 	NA	 	05270	 	131
	 33041
	 	dia & Buffer Preparat	 	E0609	 	Mixing Tank, 50 L	 	Walker	 	SP	 	5528	 	131
	 NA
	 	Cell Culture	 	95-SKR-1200	 	Orbital Shaker	 	Thermo Scientific	 	416	 	147600-508	 	129
	 NA
	 	Cell Culture	 	95-SKR-1201	 	Orbital Shaker	 	Thermo Scientific	 	416	 	147600-507	 	129
	 33189
	 	Analytical	 	NA	 	Osmometer	 	Precision Systems	 	5004	 	J302040	 	129
	 33189
	 	Cell Culture	 	NA	 	Osmometer	 	Precision Systems	 	Microsmette 5004	 	JJ02040	 	129
	 NA
	 	Cell Culture	 	E1309	 	Osmometer	 	Precision Systems	 	Microsmette 5004	 	AA01100	 	131
	 NA
	 	Cell Culture	 	NA	 	Osmometer	 	Precision Systems	 	Microsmette 5004	 	AA01120	 	131
	 33168
	 	Analytical	 	E2488	 	Osmometer, Vapor Pressure	 	Wescor	 	5520	 	5520042488	 	129
	 33183
	 	Analytical	 	E2486	 	Plate Reader, Fluorescence, Gemini EM	 	Molecular Devices	 	SpectraMax Gemini EM	 	EM01416	 	105
	 30552
	 	Cell Culture	 	E2038	 	Pump, Peristaltic	 	Watson-Marlow	 	101U/R	 	1110070	 	131
	 33123
	 	Cell Culture	 	E2036	 	Pump, Peristaltic	 	Watson-Marlow	 	101U/R	 	C071648	 	129

  
 F-8

															
	 Asset Number
	  	 Functional Area
	  	 Equipment Number
	  	 Description
	  	 Manufacturer
	  	 Model
	  	 Serial Number
	  	Room
	 33124
	  	Cell Culture	  	E2037	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	C071649	  	129
	 33126
	  	Cell Culture	  	E2040	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	1110772	  	131
	 33127
	  	Cell Culture	  	E2041	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	C071879	  	129
	 33158
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	C120404	  	129
	 IMA
	  	Analytical	  	E1774	  	Pump, Peristaltic	  	Watson-Marlow	  	504S/RL	  	A113989	  	129
	 NA
	  	Cell Culture	  	E2039	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	C071651	  	129
	 NA
	  	Cell Culture	  	E5286	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	5060061	  	131
	 NA
	  	Cell Culture	  	E5293	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	4110653	  	129
	 NA
	  	Cell Culture	  	E55285	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	4110651	  	129
	 NA
	  	Analytical	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	520U/R	  	E032284	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450796	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450805	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450797	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450790	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450804	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450792	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450801	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450790	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450794	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450802	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1517123	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450806	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450791	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450793	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1434367	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450800	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450795	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450799	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	C.P.78016-45	  	1450803	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	ISM936D	  	1426513	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	ISM936D	  	1426512	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	B013967	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	B040522	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	C021320	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	D040521	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	A052090	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	D010806	  	131

  
 F-9

															
	 Asset Number
	  	 Functional Area
	  	 Equipment Number
	  	 Description
	  	 Manufacturer
	  	 Model
	  	Serial Number	  	Room
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	C121622	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	D031394	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	D040518	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	F030904	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	1110767	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	A052086	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	C071650	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	C071880	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	D040523	  	130
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	D040527	  	130
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	D040526	  	130
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	A021138	  	130
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	B060228	  	130
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	C121620	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	F030905	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	A052088	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	A021136	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	A052087	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	5060064	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	F030867	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	1102407	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	B051902	  	129
	 NA
	  	Ceil Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	F030865	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Watson-Marlow	  	101U/R	  	D041623	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	MasterFlex	  	7520-00	  	H96007044	  	129
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	MasterFlex	  	7520-40	  	L04001754	  	131
	 NA
	  	Cell Culture	  	NA	  	Pump, Peristaltic	  	Ismatec	  	ISM404B	  	1501866	  	131
	 33116
	  	Cell Culture	  	E1874	  	Refrigerator, Upright	  	Revco Technologies	  	R429GA14	  	Z20L-561055-NM	  	154
	 33117
	  	Cell Culture	  	E1875	  	Refrigerator, Upright	  	Revco Technologies	  	R429GA14	  	Z20L-561056-NM	  	154
	 33119
	  	Utility	  	E1981	  	Refrigerator, Upright	  	VWR	  	R429GA14	  	N09M-546132-NM	  	135
	 NA
	  	Cell Culture	  	E2017	  	Roller Bottle Unit	  	Wheaton	  	4862	  	65795-286	  	157
	 33043
	  	dia & Buffer Preparation	  	E1538	  	Scale, Barrel	  	Pennsylvania	  	7507	  	98 249293	  	129
	 33024
	  	dia & Buffer Preparation	  	E1410	  	Scale, Ramp, PA	  	unknown	  	6600	  	H7209092	  	131
	 33169
	  	Analytical	  	E2372	  	Spectrophotometer, UV-Visible	  	Thermo-Fisher	  	Nicolet Evolution 300	  	EV3121703	  	129
	 32727
	  	Characterization Lab	  	95-IB-8300	  	Stability Chamber	  		  		  		  	157
	 NA
	  	Analytical	  	NA	  	Stirrer, Cimarec 2	  	Barnstead/Thermolyne	  	S46725	  	1071010978741	  	129

  
 F-10

															
	 Asset Number
	  	 Functional Area
	  	 Equipment Number
	  	 Description
	  	 Manufacturer
	  	 Model
	  	 Serial Number
	  	Room
	 NA
	  	Analytical	  	NA	  	Stirrer, Cimarec 2	  	Bamstead/Thermolyne	  	S46725	  	1071010978723	  	129
	 NA
	  	Metrology	  	E1635	  	Tachometer, Digital	  	Ametek	  	1726	  	101599004	  	136
	 33165
	  	Purification	  	NA	  	Tangential Flow Filtration System, Bench	  	Sartorius	  	ice 200 Benchtop (multiple a	  	E200-525-0604	  	129
	 33154
	  	Purification	  	E2295	  	Tangential Flow Filtration System, Pilot	  	II Life Sciences Corporate	  	Maxim UF	  	6201375/65	  	129
	 32996
	  	dia & Buffer Preparation	  	E0483	  	Tank, 50 L	  	Walker	  	SP	  	5531	  	131
	 NA
	  	Utility	  	NA	  	Telephone Network Switch	  	Avaya	  	Definity G3si	  	1004493488	  	163

  
 F-11

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00201-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00201-of-00352.parquet"}]]