Document:

Third Modification of Mortgage and Security Agreement

 Exhibit 10.8 
 THIRD MODIFICATION OF MORTGAGE AND SECURITY AGREEMENT 
 This Third Modification of Mortgage and Security Agreement (“Third Modification”) made effective as of the 30th day
of September, 2008, by and between UNIGENE LABORATORIES, INC., a Delaware corporation authorized to do business in New Jersey, having offices at 110 Little Falls Road, Fairfield, New Jersey 07004 (the “Mortgagor”), and JAY
LEVY, with an address at 2150 Center Avenue, Fort Lee, New Jersey 07024 (the “Mortgagee”). 
 WHEREAS, in connection
with a loan which Mortgagee provided to Mortgagor, Mortgagor executed and delivered a Mortgage and Security Agreement, dated July 13, 1999, to Mortgagee (the “Original Mortgage”), with respect to property located in the
Township of Fairfield, County of Essex and State of New Jersey, as more particularly described in the Original Mortgage (the “Premises”), which Original Mortgage was recorded in the Essex County Register’s Office;

 WHEREAS, in connection with certain other loans which Mortgagee provided to Mortgagor, Mortgagor executed and delivered a Modification of
Mortgage and Security Agreement to Mortgagee dated August 5, 1999 (the “First Modification”), which was recorded in the Essex County Register’s Office with respect to the Premises; 
 WHEREAS, in connection with a restructuring and consolidation of the notes which were secured by the Original Mortgage, as modified by the First
Modification (the “Amended Mortgage”), Mortgagor executed and delivered a second Modification of Mortgage and Security Agreement to Mortgagee dated May 10, 2007 (the “Second Modification”), which
was recorded in the Essex County Register’s Office with respect to the Premises; and 

 WHEREAS, Mortgagee and Mortgagor now wish to further modify the Amended Mortgage, as modified by the
Second Modification (the “Consolidated Mortgage”), by the execution and filing of this Third Modification, such that the Consolidated Mortgage, as modified by this Third Modification (the “Mortgage”),
shall be subject to the terms and conditions set forth herein. 
 NOW, THEREFORE, the parties agree as follows: 
 1. Subordination of Mortgage. This instrument and the rights, remedies and obligations evidenced hereby are subordinate in the manner and to the
extent set forth in that certain Affiliate Subordination Agreement (as amended, restated, modified or supplemented from time to time, the “Subordination Agreement”), dated as of September 30, 2008, by and among
Mortgagee, Mortgagor and Victory Park Management, LLC (“Victory”), among others, to the Senior Debt (as defined in the Subordination Agreement), that certain first priority lien Mortgage, Security Agreement, Assignment of
Rents and Leases and Fixture Filing, dated as of September 30, 2008 (the “Senior Mortgage”), by Mortgagor in favor of Victory as Agent and each other Senior Debt Document (as defined in the Subordination Agreement); and
each holder of this instrument, by its acceptance hereof, irrevocably agrees to be bound by the provisions of the Subordination Agreement. 
  

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 2. No Event of Default. Notwithstanding anything in the Mortgage to the contrary, Mortgagee does
hereby affirm that Mortgagee’s entering into the Senior Debt and the execution, delivery and performance of the Senior Mortgage and each other Senior Debt Document shall not constitute an Event of Default under the Mortgage. 
 3. Termination of Subordination. The subordination of the Mortgage evidenced hereby shall remain in full force and effect until the indefeasible
payment in full in cash of the Senior Debt and the termination of all lending commitments under the Senior Debt Documents (as defined in the Subordination Agreement), after which the subordination shall terminate without further action. 

4. Affirmation of Validity of Mortgage. Mortgagor does hereby affirm the extent and validity of the Mortgage and does confirm that, as of the
date of execution hereof, the Mortgage, as modified by the within agreement, shall constitute a continuing, valid lien upon the Premises, to secure payment of certain indebtedness. 
 5. Binding Effect. The within agreement shall be binding upon the parties hereto, their successors and assigns. 
 6. Governing Law. The within agreement shall be construed and enforced in accordance with the laws of the State of New Jersey. 
 7. Copy Acknowledge. The undersigned Mortgagor acknowledges receipt of a true copy of this document without charge. 
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 IN WITNESS WHEREOF, the parties hereto have executed this Third Modification of Mortgage and Security
Agreement as of the day and year first above written. 
  

					
	Attest:	  	Unigene Laboratories, Inc.
			
	 /s/ Ronald S. Levy
	  	By:	 	 /s/ William Steinhauer

	Ronald S. Levy, Secretary	  		 	William Steinhauer, Vice President of Finance
			
	Witness: /s/Warren P. Levy	  		 	

					
	 Attest:
	  		 	
			
	 /s/ Warren P. Levy
	  	By:	 	 /s/ Jay Levy

	Witness:	  		 	JAY LEVY

					
	STATE OF NEW JERSEY	  	)	  	
		  	)	  	ss:
	COUNTY OF ESSEX	  	)	  	

 I certify that on September 30, 2008, Ronald S. Levy personally came before me and this
person acknowledged under oath, to my satisfaction, that: 
  

	 	(a)	this person is the Secretary of Unigene Laboratories, Inc., the corporation named in this document; 

  

	 	(b)	this person is the attesting witness to the signing of this document by the proper corporate officer who is William Steinhauer, the Vice President of Finance of the corporation;

  

	 	(c)	this document was signed and delivered by the corporation as its voluntary act duly authorized by a proper resolution of its Board of Directors; 

  

	 	(d)	this person knows the proper seal of the corporation which was affixed to this document; and 

  

	 	(e)	this person signed this proof to attest to the truth of these facts. 

 Sworn and Subscribed to this 
 30th
 day of September, 2008 
  

	
	 /s/ Linda L. Rohloff

 Notary Information: 
 LINDA L. ROHLOFF 
 Notary Public, State of New Jersey 
 County of Passaic 
 Registration No. 2057307 
 Commission Expires April 11, 2009 

					
	STATE OF NEW JERSEY	  	)	  	
		  	)	  	ss:
	COUNTY OF ESSEX	  	)	  	

 On this 30th day of September, 2008, before me, Linda L. Rohloff, the undersigned officer, personally appeared JAY LEVY to me personally known and known to
me to be the same person whose name is signed to the foregoing instrument, and acknowledged the execution thereof for the uses and purposes therein set forth. 
 In WITNESS WHEREOF I have hereunto set my hand and official seal. 
 Sworn and Subscribed to this 
 30th day of
September, 2008 
  

	
	 /s/ Linda L. Rohloff

 Notary Information: 
 LINDA L. ROHLOFF 
 Notary Public, State of New Jersey 
 County of Passaic 
 Registration No. 2057307 
 Commission Expires April 11, 2009Lock-Up Agreement

 Exhibit 10.9 
 LOCK-UP AGREEMENT 
 This LOCK-UP AGREEMENT (this “Agreement”), dated as of
September 30, 2008, is entered into by and among Unigene Laboratories, Inc., a Delaware corporation (the “Company”), and the lender(s) listed on the signature page hereto (each, a “Holder” and collectively, the
“Holders”). 
 WHEREAS: 
 A. In connection with that certain Financing Agreement, dated as of even date herewith, by and among the Company, Victory Park Management, LLC, as administrative agent and collateral agent, and the Holders (the
“Financing Agreement”), the Company has agreed, upon the terms and subject to the conditions of the Financing Agreement, to issue and sell on the date hereof to each Holder certain shares of the Company’s common stock, par
value $0.01 per share (the “Common Stock”). 
 B. To induce the Company to execute and deliver the Financing
Agreement, each Holder has agreed to enter into this Agreement. 
 C. This Agreement constitutes a Transaction Document (as defined in
the Financing Agreement). 
 NOW, THEREFORE, in consideration of the premises and the mutual covenants contained herein and other good
and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Company and each of the Buyers hereby agree as follows: 
 1. For a period of one (1) year from the date hereof (the “Lock-Up Period”), no Holder will, without the prior written consent of the Company, directly or indirectly, (i) offer, sell,
assign, transfer, pledge, contract to sell (if such sale would or could be consummated within the Lock-Up Period) or otherwise dispose of (collectively, “Transfer”) any shares of Common Stock issued to such Holder pursuant to the
Financing Agreement (“Financing Shares”). For the purpose hereof, the term “Transfer” includes the entry into any swap, hedge or similar agreement or arrangement that transfers, in whole or in part, the economic
risk of ownership of the Financing Shares or any short selling of the Financing Shares; provided, however, that nothing in this Agreement shall prevent a Holder from entering into any legally permissible hedge or collar transaction (or
similar transaction) that does not permit or require the Financing Shares to be transferred into the open market or that does not result in a change of beneficial ownership of the Financing Shares prior to the expiration of the Lock-Up Period.

 2. Notwithstanding the foregoing, each Holder may (a) transfer any or all of the Financing Shares, as the case may be, by gift, will
or intestacy, (b) pledge the Financing Shares in connection with a bona fide margin account or other loan or financing arrangement secured by the Financing Shares or (c) transfer any or all of its Financing Shares to a partner or affiliate
of such Holder; provided, however, that in any such case it shall be a condition to the transfer or pledge that the transferee or pledgee execute an agreement stating that the transferee or pledgee is receiving and holding the
Financing Shares subject to the provisions of this Agreement, and there shall be no further transfer of the Financing Shares except in accordance with this Agreement. 

 3. Each Holder agrees that the Company may, and in the case of clause (ii) that such Holder will,
(i) with respect to any Financing Shares for which such Holder is the record holder, cause the transfer agent for the Company to note stop transfer instructions with respect to such Financing Shares on the transfer books and records of the
transfer agent or the Company, as applicable, and (ii) with respect to any Financing Shares for which such Holder is the beneficial holder but not the record holder, cause the record holder of such Financing Shares to cause the transfer agent
for the Company to note stop transfer instructions with respect to such Financing Shares on the transfer books and records of the transfer agent or the Company, as applicable. 
 4. Provisions of this Agreement may be amended and the observance thereof may be waived (either generally or in a particular instance and either
retroactively or prospectively) only with the written consent of the Company and the Holders. All questions concerning the construction, validity, enforcement and interpretation of this Agreement shall be governed by the internal laws of the State
of Illinois, without giving effect to any choice of law or conflict of law provision or rule (whether of the State of Illinois or any other jurisdictions) that would cause the application of the laws of any jurisdiction other than the State of
Illinois. 
 5. The language used in this Agreement will be deemed to be the language chosen by the parties to express their mutual intent
and no rules of strict construction will be applied against any party. 
 6. This Agreement may be executed in identical counterparts, each
of which shall be deemed an original but all of which shall constitute one and the same agreement. This Agreement, once executed by a party, may be delivered to the other party hereto by facsimile transmission of a copy of this Agreement bearing the
signature of the party so delivering this Agreement. 
 7. Upon the earlier of (i) the occurrence of any Event of Default (as defined in
the Financing Agreement) of the type described in Section 10.1(c), (d) or (g) of the Financing Agreement and (ii) thirty (30) days following the occurrence of any other Event of Default (without giving effect to any cure
period set forth therein) unless such Event of Default shall have been cured prior thereto, in either case this Agreement shall automatically and irrevocably terminate and be of no further force or effect. 
 *  *  *  *  *  * 
  

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 IN WITNESS WHEREOF, each Holder and the Company has caused its signature page to this Lock-Up
Agreement to be duly executed as of the date first written above. 
  

			
	 COMPANY:

	
	 UNIGENE LABORATORIES, INC.

		
	By:	 	 /s/ Warren P. Levy

	Name:	 	Warren Levy
	Title:	 	Chief Executive Officer
	
	HOLDER:
	
	VICTORY PARK SPECIAL SITUATIONS MASTER FUND, LTD.
		
	By:	 	Victory Park Capital Advisors, LLC, its investment manager
		
	By:	 	 /s/ Scott Zemnick

	Name:	 	Scott Zemnick
	Title:	 	General Counsel

 [Signature Page to Lock-Up Agreement]

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