Document:

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                                                                   Exhibit 10.21

                                 FIRST AMENDMENT
                                       TO
                              CONSULTING AGREEMENT

         This First Amendment (this "AMENDMENT") is entered into this 21st day
of August, 2002 between Mymetics Corporation, a Delaware corporation (the
"COMPANY"), and Michael Allio, an individual resident of Rhode Island (the
"CONSULTANT").

                                    PREAMBLE

         The parties entered into that certain Consulting Agreement (the
"AGREEMENT") dated as of August 31, 2001. The Company and the Consultant are
desirous of amending the Agreement in accordance with the provisions of this
Amendment. Therefore, the parties, intending to be legally bound hereby, agree
as follows:

                                    AGREEMENT

         1. All defined terms used herein and not otherwise defined shall have
the meaning set forth in the Agreement.

         2. The term of the Agreement shall be extended to February 28, 2003,
unless terminated earlier in accordance with the provision of Section 3 of the
Agreement.

         3. Effective July 1, 2002, the monthly amount payable to the Consultant
in accordance with Section 2(a) of the Agreement shall be increased to $16,500.
If the Consultant's engagement hereunder should require more than the 7.5 days
of full time work per month alloted under the Agreement, the Consultant shall
invoice the Company for such additional time at a rate of $2,500 per diem, and
the Company shall pay such invoices within 30 days of receipt thereof.

         4. Section 2(b) of the Agreement is deleted in its entirety and in its
stead is inserted the following:

            "(b) Stock Options. In addition to the compensation set forth in (a)
above, the Consultant shall be granted stock options to purchase up to 50,000
shares of the Company's common stock, $0.01 par value, pursuant to the Company's
2001 Stock Option Plan (the "INITIAL STOCK OPTION"). The exercise price for the
Initial Stock Option will be $2.50 per share of commons stock, which represents
the average of the bid and ask price of such shares as of September 1, 2001. In
addition, the Company agrees to grant the Consultant stock options for an
additional 100,000 shares of the Company's common stock, $0.01 par value,
pursuant to the Company's 2001 Stock Option Plan (the "SECONDARY STOCK OPTION"
and, together with the Initial Stock Option, the "STOCK OPTIONS"). The exercise
price for the Secondary Stock Option will be $0.55 per share,

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which represents the average of the bid and ask price of such shares as of
August 15, 2002. The Consultant agrees to execute a Stock Option Agreement in
substantially the form of Exhibit A, attached hereto an incorporated by
reference herein, upon the grant of each of the Stock Options. Each of the Stock
Options will vest upon being granted."

         5. All other provisions of the Agreement shall continue to remain in
effect.

ATTEST:                                 MYMETICS CORPORATION

_________________________________       By: /s/ Peter P. McCann
                                           -----------------------------------
                                        Name:  Peter P. McCann
                                        Title:  President and CEO
WITNESS:

_________________________________       /s/ Michael Allio
                                        --------------------------------------
                                        Michael Allio<PAGE>

                                                                   Exhibit 10.23

                        SEPARATION AGREEMENT AND RELEASE

         THIS AGREEMENT is entered into this 31st day of January, 2003, by and
between MYMETICS CORPORATION, a Delaware corporation ("Mymetics"), and DR. PETER
P. MCCANN ("Employee").

         WHEREAS, Employee has been employed by Mymetics as its President and
Chief Executive Officer as set forth in the Employment Agreement by and between
Mymetics and Employee dated March 18, 2002 (the "Employment Agreement"); and

         WHEREAS, Mymetics has decided to terminate the Employment Agreement;
and

         WHEREAS, Employee has agreed to resign from his position on the Board
of Directors of Mymetics and resign from all other positions he holds with
Mymetics and its affiliates and subsidiaries; and

         WHEREAS, Mymetics and Employee desire to set forth the terms and
conditions of Employee's resignation; and

         WHEREAS, this Agreement is being offered solely for the purpose of
attempting to settle any and all existing or potential outstanding disputes
between the parties and is not an admission of any obligations or liability;

         NOW THEREFORE, in consideration of the settlement of any claims that
either party to this Agreement may have against the other arising out of the
employment relationship between the parties hereto and/or the termination of the
Employee's employment with Mymetics and/or the March 18, 2002 Employment
Agreement and/or any and all claims arising thereunder now or hereafter, and
intending to be legally bound, the parties do hereby agree as follows:

                                    AGREEMENT

         1. TERMINATION OF EMPLOYMENT AGREEMENT. The Employment Agreement, which
is incorporated herein by reference, is terminated effective as of January 31,
2003, except for Sections 5.1, 5.2, 5.3, and 5.4, which will survive the
termination of the Employment Agreement and shall remain in full force and
effect.

         2. RESIGNATION FROM EMPLOYMENT. Employee agrees to resign from his
position on the Board of Directors of Mymetics and resign from all other
positions he holds with Mymetics and its affiliates and subsidiaries effective
as of January 31, 2003. Employee agrees that he will leave Mymetics in an
orderly, non-disruptive fashion.

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         3. CONSIDERATION. As consideration for entering into this Agreement,
Mymetics agrees to grant, pursuant to Mymetics Stock Option Plan, to Employee
seventy-five thousand (75,000) options for Mymetics stock at a price to be
determined as the trading value of Mymetics stock on January 31, 2003. Said
grant will be made on January 31, 2003.

         Employee acknowledges that the consideration set forth in this
Agreement constitutes consideration over and above anything of value that he
would be entitled to but for this Agreement. Employee's acceptance of the
consideration to be made hereunder is in full accord and satisfaction of all
claims arising out of Employee's employment with Mymetics and/or the termination
of the Employment Agreement, including but not limited to breach of contract,
tort, or any federal, state, or municipal statute or ordinance relating to
employment including, without limitation, any claim for wrongful discharge
(under any state or federal law or statute), breach of contract, benefits under
the plans, incentive compensation, vacation benefits, or other common law claims
or claims in equity. Employee agrees that all benefits and incidents of his
employment relationship with Mymetics ceased on January 31, 2003.

         4.       NON-DISPARAGEMENT AND CONFIDENTIALITY.

                  (a) Employee agrees that he will not in any way disparage or
make negative comments regarding Mymetics or its directors, officers, employees,
agents, attorneys, or consultants to any person. Mymetics, its directors,
officers, employees, agents, attorneys, and consultants agree that they will not
in any way disparage or make negative comments regarding Employee.

                  (b) The terms, conditions, amount, and fact of this Agreement
(other than the fact of Employee's prior employment and his resignation), and
the reasons therefor, shall at all times remain confidential. Neither Employee
nor Mymetics will make, facilitate, or authorize any disclosure concerning this
Agreement, or the reasons therefor, except for disclosures to Employee's
immediate family, legal counsel and/or accountants for the respective parties,
or as may be required by applicable laws, regulations, or judicial,
governmental, or similar order or decree.

         5. NO ADMISSION OF LIABILITY. This Agreement will not constitute nor be
deemed or construed to be an admission by Mymetics of discrimination of any kind
or nature whatsoever against Employee or of any breach of any obligation of any
kind or nature whatsoever, express or implied, to Employee. This Agreement shall
not be deemed or construed to be an admission by Employee of any act of
impropriety or wrongdoing.

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         6.       COOPERATION AND RETURN OF PROPERTY.

                  (a) Employee agrees to cooperate fully with Mymetics, its
counsel, and other representatives with respect to any and all legal disputes
involving matters arising during his employ in which he was involved or in which
he is knowledgeable of relevant information. Employee further agrees to
cooperate fully with Mymetics to complete the transition of all matters with
which Employee is familiar or for which Employee has responsibility and to be
reasonably available to answer questions and assist in such matters.

                  (b) Promptly following the execution hereof, Employee shall
return to Mymetics any and all tangible personal property that belongs to
Mymetics and that is in Employee's possession. Such property may consist of,
without limitation, computers, fax machines, books and other resource materials,
office supplies, communications equipment, documents, files, computer disks and
other electronic media, tools, equipment, and other property of Mymetics,
including all correspondence, memoranda, drawings, blueprints, manuals, letters,
notes, reports, flow-charts, training and marketing materials, and related
documents, proposals, plans, and any documents concerning Mymetics' customers or
prospective customers or concerning products or processes used or developed by
Mymetics. Without limiting the foregoing, Employee will promptly deliver to
Mymetics any and all other documents or materials containing or constituting
confidential or proprietary information (as described in the Employment
Agreement).

         7. RELEASE. Employee does hereby absolutely, irrevocably, and
unconditionally release and forever discharge Mymetics and its successors,
assigns, directors, officers, employees, agents, and attorneys from any and all
actions, causes of actions, damages (including but not limited to wages,
benefits, emotional distress, pain and suffering, humiliation), suits, claims,
complaints, costs, and demands whatsoever, at law or in equity, which he ever
had, now has, or hereafter may have, whether known or unknown by him as of the
date hereof, by reason of or in any way related to his employment, separation
from employment, loss of employment, ownership (if any) of equity or stock
options to purchase equity in Mymetics, or the forfeiture or termination of such
equity or the right to obtain such equity, including but not limited to breach
of contract, breach of fiduciary duty, shareholder derivative claims (or similar
shareholder claims), tort, or any federal, state, or municipal statute or local
ordinance relating to employment including, without limitation, any claim for
wrongful discharge, breach of contract, benefits under plans or programs,
including without limitation, any severance or termination pay program, or other
common law claims or claims in equity and all statutes and ordinances concerning
employment discrimination on account of, but not limited to, sex, race, age,
religion, national origin, familial status, military status, and disability,
including without limitation, Title VII of the Civil Rights Act of 1964, as
amended, the Age Discrimination in Employment Act, as amended, the Older Workers
Benefit Protection Act, the Americans with Disabilities Act, the Employee
Retirement Income Security Act, Delaware's Discrimination in Employment Law,
Maryland's fair

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employment practices laws, Delaware's Wage Payment and Collection Act, and the
Maryland Wage Payment and Collection Law. In addition, Employee also releases
Mymetics and waives any right to or claim for any and all attorneys' fees,
including litigation expenses and costs that Employee or his counsel may claim
under any statute, regulation, or at common law or in equity, including but not
limited to those set forth in this Section.

         8. RECOVERY OF PAYMENTS. This Agreement may be pled as a complete
defense and bar to any claims Employee may bring against Mymetics arising in any
way from his employment with Mymetics or resignation therefrom. In the event a
court of competent jurisdiction determines that Employee breached any of his
obligations hereunder, Mymetics will be entitled to recover the consideration
given under this Agreement and to obtain all other relief provided by law or
equity.

         9. JUDICIAL ENFORCEMENT. Ten (10) days before any party hereto
institutes any action to enforce the rights set forth in this Agreement, written
notice of the intention to sue shall be given by certified mail by said party to
the other party. During the above-mentioned ten (10) day period, the parties
hereto will make a reasonable effort to amicably resolve any disagreement that
has arisen between them.

         10. GOVERNING LAW. Should any dispute arise concerning the
interpretation of this Agreement, it will be interpreted under the laws of the
State of Delaware.

         11. CONSULTATION WITH COUNSEL. Employee is advised to consult an
attorney about this Agreement, and by executing this Agreement, Employee
acknowledges that he has been so advised.

         12. ATTORNEYS' FEES. Each party shall pay its own legal fees and
expenses in connection with this Agreement.

         13. ENTIRE AGREEMENT. This Agreement contains the entire agreement of
the parties with respect to the matters contemplated hereby and supersedes all
prior written and oral agreements, and all contemporaneous oral agreements,
relating to such transactions.

         14. ARBITRATION. Any controversy, claim, or dispute between the parties
concerning this Agreement or the breach thereof shall be finally settled by
arbitration in Pittsburgh, Pennsylvania, pursuant to the rules of the American
Arbitration Association regarding employment disputes. In such instances, it is
agreed that the dispute shall be submitted to final and binding arbitration by
one arbitrator; provided, however, that either party may request that there be
three arbitrators, in which case each party shall select one arbitrator, and the
two arbitrators so selected shall select a third. All costs of arbitration
(other than the costs of a party's own witnesses and professional advisors)
shall be split equally between the parties.

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         15. EQUITABLE RELIEF. Notwithstanding Section 14 "Arbitration," the
parties acknowledge and agree that each would be irreparably damaged in the
event that any of the provisions of this Agreement are not performed by the
other in accordance with their specific terms or are otherwise breached.
Accordingly, it is agreed that the non-breaching party shall be entitled to an
injunction or injunctions to prevent breaches of this Agreement by the other
party and shall have the right to specifically enforce this Agreement and the
terms and provisions hereof against the breaching party in addition to any other
remedy to which the non-breaching party may be entitled at law or in equity. The
parties further agree that Section 14 "Arbitration" is not intended to be a bar
to either party seeking injunctive relief by filing an action in an appropriate
court.

         16. HEADINGS. All titles and headings in this Agreement are intended
solely for convenience of reference and shall in no way limit or otherwise
affect the interpretation of any of the provisions hereof.

         17. ASSIGNMENT. This Agreement shall inure to the benefit of, and be
binding upon, the heirs, executors, administrators, and assigns of the Employee
and upon the successors and assigns of Mymetics and the other members of
Mymetics, provided that this clause does not in any way alter the rights of the
Employee with respect to the Mymetics Stock Option Plan or grant to the Employee
the right to assign the Mymetics Stock Option Plan or any of them, or any of his
rights thereunder.

         18. SEVERABILITY. Should any provision of this Agreement be declared
illegal or unenforceable by any court of competent jurisdiction and cannot be
modified to be enforceable, including the general release language, such
provision shall immediately become null and void, leaving the remainder of this
Agreement in full force and effect. However, if any portion of the general
release language were ruled to be unenforceable as a result of an action filed
by Employee or at Employee's direction, Employee shall return the consideration
given hereunder to Mymetics. Provided, however, Mymetics and Employee shall
first use their best efforts to negotiate in good faith an enforceable general
release.

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         By signing this Separation Agreement and Release, the parties hereto
acknowledge that they understand this Agreement and enter into it voluntarily,
that this is a complete settlement and release agreement and that there are no
written or oral understandings or agreements that are not set forth herein.

         WITNESS the due execution hereof as of the date first set forth above.

                                        MYMETICS CORPORATION

                                        By:/s/Michael K. Allio
                                           ------------------------------------
                                           MICHAEL K. ALLIO
                                           CHAIRMAN OF THE BOARD

                                        Dated:
                                              ---------------------------------

WITNESS:

____________________________            /s/ Peter P. McCann
                                           ------------------------------------
                                        DR. PETER P. MCCANN

                                        Dated:
                                              ---------------------------------

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