Document:

exv4w3

 

Exhibit 4.3

WARRANT

THE WARRANT EVIDENCED HEREBY AND THE COMMON STOCK ISSUABLE UPON EXERCISE HEREOF ARE SUBJECT TO A
SHAREHOLDER AGREEMENT BY AND AMONG ZARS, INC. AND THE SHAREHOLDERS OF ZARS, INC.

THIS WARRANT AND THE COMMON STOCK ISSUABLE UPON EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE
SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), AND MAY NOT BE TRANSFERRED EXCEPT PURSUANT TO AN
EFFECTIVE REGISTRATION UNDER THE ACT OR IN A TRANSACTION WHICH, IN THE OPINION OF COUNSEL
REASONABLY SATISFACTORY TO ZARS, INC., QUALIFIES AS AN EXEMPT TRANSACTION UNDER THE ACT AND THE
RULES AND REGULATIONS PROMULGATED THEREUNDER.

ZARS, INC.

Stock Purchase Warrant

     ZARS, Inc., a [Utah] corporation (the “Company”), hereby certifies that, for value received,
                    , or assigns (the “Holder”), is entitled to purchase from the Company, subject to the
terms set forth below, at the price of Four AND 86/100ths Dollars ($4.86) per share (the “Exercise
Price”), up to                      (       ) shares of the Company’s voting common stock, par value $0.12
(the “Common Stock). This Warrant is herein called the “Warrant.”

          1. Exercise of Warrant. The purchase rights evidenced by this Warrant shall be
exercised by the Holder surrendering this Warrant, with the form of subscription at the end hereof
duly executed by such holder, to the Company at its offices at 1142 West 2320 South Suite A Salt
Lake City, Utah or such other location as the parties may agree, accompanied by payment, in cash,
by certified or official bank check or by wire transfer of an amount equal to the Exercise Price
multiplied by the number of shares being purchased pursuant to such exercise of the Warrant. This
Warrant may be exercised for less than the full number of shares of Common Stock, in which case the
number of shares receivable upon the exercise of this Warrant as a whole, and the sum payable upon
the exercise of this Warrant as a whole, shall be proportionately reduced. Upon any such partial
exercise, the Company at its expense will forthwith issue to the Holder a new Warrant or Warrants
of like tenor calling for the number of shares of Common Stock as to which rights have not been
exercised, such Warrant or Warrants to be issued in the name of the Holder.

          2. Delivery of Stock Certificates on Exercise. As soon as practicable after the
exercise of this Warrant and payment of the Exercise Price, and in any event within ten (10) days

 

 

thereafter, the Company, at its expense, will cause to be issued in the name of and delivered
to the Holder hereof a certificate or certificates for the number of fully paid and non-assessable
shares to which such Holder shall be entitled upon such exercise. The Company agrees that the
shares so purchased shall be deemed to be issued to the Holder hereof as the record owner of such
shares as of the close of business on the date on which this Warrant shall have been surrendered
and payment made for such shares as aforesaid.

          3. Exercise Date and Term of Warrant. Unless accelerated as described in Section 4
below, the Holder shall not be entitled to exercise this Warrant until a period of one year after
February 27, 2004 (the “Exercise Date”). Holder shall have from the Exercise Date until May 31,
2013, in which to exercise this Warrant, at which time all of the Holder’s rights hereunder shall
terminate. Moreover, this Warrant shall expire, and the Holder shall have no rights hereunder,
unless the Holder has been continuously and actively involved with the affairs of the Company, by
providing meaningful services to the Company or its subsidiaries, from the date hereto until the
Exercise Date.

          4. Acceleration of Exercise Date. In the event the Company enters into an agreement to
sell a majority of its assets, the Exercise Date shall be accelerated and shall be the date on
which the Company enters into such agreement. In such an event, the Company shall provide notice to
the Holder in accordance with this Warrant.

          5. Shareholder Agreement. Upon exercise of this Warrant and at the request of the
Company, the Holder shall execute and deliver to the Company a Shareholder Agreement or Statement
of Acceptance thereof prior to the transfer or delivery of any shares and prior to the expiration
of the Exercise Period. The Company shall have no obligation to transfer or deliver the shares
issued pursuant to this Warrant unless or until the Holder executes and delivers the foregoing to
the Company.

          6. No Impairment. The Company will not, by amendment of its articles of incorporation
or through reorganization, consolidation, merger, dissolution, sale of assets or any other
voluntary action, avoid or seek to avoid the observance or performance of any of the terms of this
Warrant, but will at all times in good faith assist in the carrying out of all such terms and in
the taking of all such action as may be necessary or appropriate in order to protect the rights of
the Holder against impairment. Without limiting the generality of the foregoing, the Company will
not increase the par value of any shares of stock receivable upon the exercise of this Warrant
above the amount payable therefor upon such exercise, and at all times will take all such action as
may be necessary or appropriate in order that the Company may validly and legally issue fully paid
and non-assessable stock upon the exercise of this Warrant and all other Warrants at the time
outstanding.

          7. Reservation of Stock, Etc., Issuable on Exercise of Warrants. The Company shall at
all times reserve and keep available out of its authorized but unissued stock,

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solely for the issuance and delivery upon the exercise of this Warrant and other similar
Warrants, such number of its duly authorized shares of Common Stock as from time to time shall be
issuable upon the exercise of this Warrant, and all other Warrants at the time outstanding.

          8. Assignment or Transfer Prohibited: This Warrant is not transferable by the Holder
other than by will or the laws of descent and distribution, and this Warrant shall be exercisable
during the Holder’s lifetime only by the Holder. This Warrant shall become null and void in the
event the Holder attempts to transfer, assign, pledge, hypothecate or otherwise dispose of this
Warrant contrary to the provisions hereof.

          9. Miscellaneous.

               a. Replacement of Warrant. Upon receipt of evidence reasonably satisfactory to the
Company of the loss, theft, destruction or mutilation of this Warrant and (in the case of loss,
theft or destruction) upon delivery of an indemnity agreement (with surety if reasonably required)
in an amount reasonably satisfactory to it, or (in the case of mutilation) upon surrender and
cancellation thereof, the Company will issue, in lieu thereof, a new Warrant of like tenor.

               b. Remedies. The Company stipulates that the remedies at law of the Holder in the
event of any default by the Company in the performance of or compliance with any of the terms of
this Warrant are not and will not be adequate, and that the same may be specifically enforced.

               c. Rights Prior to Exercise. Prior to the exercise of this Warrant, the Holder shall
not be entitled to any rights of a shareholder of the Company with respect to shares for which this
Warrant shall be exercisable, including, without limitation, the right to vote, to receive
dividends or other distributions, and shall not be entitled to receive any notice of any
proceedings of the Company.

               d. Subdivision of Rights. This Warrant (as well as any new warrants issued pursuant to
the provisions of this paragraph) is exchangeable, upon the surrender hereof by the Holder, at the
principal office of the Company for any number of new warrants of like tenor and date representing
in the aggregate the right to subscribe for and purchase the number of shares of Common Stock of
the Company which may be subscribed for and purchased hereunder.

               e. Mailing of Notices, Etc. All notices and other communications from the Company to
the Holder shall be mailed by first-class certified mail, postage prepaid, to the address furnished
to the Company in writing.

 3.

 

               f. Headings, Etc. The headings in this Warrant are for purposes of reference only, and
shall not limit or otherwise affect the meaning hereof.

               g. Change, Waiver, Etc. Neither this Warrant nor any term hereof may be changed,
waived, discharged or terminated orally but only by an instrument in writing signed by the party
against which enforcement of the change, waiver, discharge or termination is sought.

               h. Governing Law. This Warrant shall be construed and enforced in accordance with the
laws of the State of Utah.

	 	 	 	 	 
	 	ZARS, INC.
 	 	 
	 
	 	By  	 	 
	 
	 	 	Name:  	Larry Rigby 	 
	 
	 	Title:  	              President 	 
	 

Dated: June 7, 2004

 4.

 

[To be signed only upon exercise of Warrant]

To ZARS, Inc.

     The undersigned, the holder of the within Warrant, hereby irrevocably elects to exercise the
purchase right represented by such Warrant for, and to purchase thereunder,                      shares of
Common Stock of ZARS, Inc. and herewith makes payment of $
_____ therefor, and requests that the
certificates for such shares be issued in the name of, and be delivered to the undersigned, whose
address is                                         .

Dated:

                                        

	 	 	 
	 

	 	 
	 

	 	(Signature must conform in all respects to name of
	 

	 	Holder as specified on the face of the Warrant)
	 
	 	 
	 
	 

	 	 
	 

	 	Address

 

 

Schedule
to Form of Common Stock Warrant

	 	 	 	 	 	 	 	 	 	 	 	 	 
	Name	 	Date	 	 	Shares	 	 	Price	 
	 
	Busch, Michael
	 	 	2/27/2004	 	 	 	2,000	 	 	$	4.86	 
	Dow Pharmaceutical
	 	 	5/18/2001	 	 	 	15,000	 	 	$	4.86	 
	Grosser, Bernard
	 	 	4/1/2003	 	 	 	500	 	 	$	4.86	 
	Krueger, Gerald
	 	 	4/25/2006	 	 	 	1,750	 	 	$	3.41	 
	Leazer, Richard
	 	 	2/28/2000	 	 	 	12,000	 	 	$	2.50	 
	Leazer, Richard
	 	 	2/27/2004	 	 	 	2,000	 	 	$	4.86	 
	Lippert, Robert
	 	 	7/21/2003	 	 	 	1,000	 	 	$	4.86	 
	Patel, Dinesh
	 	 	5/5/2004	 	 	 	3,000	 	 	$	4.86	 
	Patel, Dinesh
	 	 	2/14/2003	 	 	 	3,000	 	 	$	4.86	 
	Rigby, Larry
	 	 	2/27/2004	 	 	 	20,000	 	 	$	4.86	 
	Rudd, David
	 	 	2/28/2000	 	 	 	12,000	 	 	$	2.50	 
	Venture
Spark, Inc.
	 	 	8/30/2004	 	 	 	208	 	 	$	4.86	 
	Venture
Spark, Inc.
	 	 	5/18/2001	 	 	 	7,202	 	 	$	4.86	 
	Venture
Spark, Inc.
	 	 	5/18/01	 	 	 	7,202	 	 	$	4.86	 
	Stanley,
Theodore H.
	 	 	8/5/2004	 	 	 	5,000	 	 	$	4.86	 
	Stanley,
Theodore H.
	 	 	2/27/2004	 	 	 	15,000	 	 	$	4.86	 
	Talmage, Egan
	 	 	10/5/2004	 	 	 	1,000	 	 	$	2.00	 
	Coast
Ventures
	 	 	8/30/2004	 	 	 	139	 	 	$	4.86	 
	Viscomi, Christopher
	 	 	5/25/2005	 	 	 	500	 	 	$	2.00	 
	Weinschenker, Ned
	 	 	3/31/2000	 	 	 	9,000	 	 	$	2.50	 
	 
	 	 	 	 	 	 	 	 	 	 	 
	 
	 	Total	 	 	117,501	 	 	 	 	 
	 
	 	 	 	 	 	 	 	 	 	 	 

 

 

THE WARRANT EVIDENCED HEREBY AND THE COMMON STOCK ISSUABLE UPON EXERCISE HEREOF ARE SUBJECT TO A
SHAREHOLDER AGREEMENT BY AND AMONG ZARS, INC. AND THE SHAREHOLDERS OF ZARS, INC.

THIS WARRANT AND THE COMMON STOCK ISSUABLE UPON EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE
SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), AND MAY NOT BE TRANSFERRED EXCEPT PURSUANT TO AN
EFFECTIVE REGISTRATION UNDER THE ACT OR IN A TRANSACTION WHICH, IN THE OPINION OF COUNSEL
REASONABLY SATISFACTORY TO ZARS, INC., QUALIFIES AS AN EXEMPT TRANSACTION UNDER THE ACT AND THE
RULES AND REGULATIONS PROMULGATED THEREUNDER.

ZARS, INC.

Stock Purchase Warrant

     ZARS, Inc., a Utah corporation (the “Company”), hereby certifies that, for value
received,                     , or assigns (the “Holder”), is entitled to purchase from the
Company, subject to the terms set forth below, at the price of Four Dollars and eighty-six cents
($4.86) per share (the “Exercise Price”), up to                      (          ) shares of the
Company’s voting common stock, par value $0.12 (the “Common Stock”). This Warrant is herein called
the “Warrant.”

     10. Exercise of Warrant. The purchase rights evidenced by this Warrant shall be exercised by
the Holder surrendering this Warrant, with the form of subscription at the end hereof duly executed
by such holder, to the Company at its offices at 1142 West 2230 South, Suite A, Salt Lake City,
Utah 84119 or such other location as the parties may agree. The purchase rights evidenced by this
Warrant may be exercised by the Holder surrendering this Warrant without payment of any cash or
other additional consideration. This Warrant may be exercised for less than the full number of
shares of Common Stock, in which case the number of shares receivable upon the exercise of this
Warrant as a whole, and the sum payable upon the exercise of this Warrant as a whole, shall be
proportionately reduced. Upon any such partial exercise, the Company at its expense will forthwith
issue to the Holder a new Warrant or Warrants of like tenor calling for the number of shares of
Common Stock as to which rights have not been exercised, such Warrant or Warrants to be issued in
the name of the Holder.

     11. Delivery of Stock Certificates on Exercise. As soon as practicable after the exercise of
this Warrant, and in any event within ten (10) days thereafter, the Company, at its expense, will
cause to be issued in the name of and delivered to the Holder hereof a certificate or certificates
for the number of fully paid and non-assessable shares to which such Holder shall be entitled upon
such exercise. The Company agrees that the shares so purchased shall be deemed to

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be issued to the Holder hereof as the record owner of such shares as of the close of business
on the date on which this Warrant shall have been surrendered and payment made for such shares as
aforesaid.

     12. Exercise Date and Term of Warrant. Unless accelerated as described in Section 4 below,
the Holder shall not be entitled to exercise this Warrant until December 1, 2004 (the “Exercise
Date”). Holder shall have from the Exercise Date until December 1, 2010, in which to exercise this
Warrant, at which time all of the Holder’s rights hereunder shall terminate.

     13. Acceleration of Exercise Date. In the event the Company enters into an agreement to sell,
convey or dispose of all or substantially all of the Company’s property or business or the
Company’s merger with or into or consolidation with any other corporation (other than a
wholly-owned subsidiary of the corporation) or if the Company effects any other transaction or
series of related transactions in which more than fifty percent (50%) of the voting power of the
Company is disposed of, the Exercise Date shall be accelerated and shall be the date on which the
Company enters into such transaction. In such an event, the Company shall provide notice to the
Holder in accordance with this Warrant.

     14. Shareholder Agreement. Upon exercise of this Warrant and at the request of the Company,
the Holder shall execute and deliver to the Company a Shareholder Agreement or Statement of
Acceptance thereof prior to the transfer or delivery of any shares and prior to the expiration of
the Exercise Period. The Company shall have no obligation to transfer or deliver the shares issued
pursuant to this Warrant unless or until the Holder executes and delivers the foregoing to the
Company.

     15. No Impairment. The Company will not, by amendment of its articles of incorporation or
through reorganization, consolidation, merger, dissolution, sale of assets or any other voluntary
action, avoid or seek to avoid the observance or performance of any of the terms of this Warrant,
but will at all times in good faith assist in the carrying out of all such terms and in the taking
of all such action as may be necessary or appropriate in order to protect the rights of the Holder
against impairment. Without limiting the generality of the foregoing, the Company will not
increase the par value of any shares of stock receivable upon the exercise of this Warrant above
the amount payable therefor upon such exercise, and at all times will take all such action as may
be necessary or appropriate in order that the Company may validly and legally issue fully paid and
non-assessable stock upon the exercise of this Warrant and all other Warrants at the time
outstanding.

     16. Reservation of Stock, Etc., Issuable on Exercise of Warrants. The Company shall at all
times reserve and keep available out of its authorized but unissued stock, solely for the issuance
and delivery upon the exercise of this Warrant and other similar Warrants, such number of its duly
authorized shares of Common Stock as from time to time shall be issuable upon the exercise of this
Warrant, and all other Warrants at the time outstanding.

2

 

     17. Assignment or Transfer Prohibited. This Warrant is not transferable by the Holder other
than by will or the laws of descent and distribution, and this Warrant shall be exercisable during
the Holder’s lifetime only by the Holder. This Warrant shall become null and void in the event the
Holder attempts to transfer, assign, pledge, hypothecate or otherwise dispose of this Warrant
contrary to the provisions hereof.

     18. Miscellaneous.

          a. Replacement of Warrant. Upon receipt of evidence reasonably satisfactory to the Company of
the loss, theft, destruction or mutilation of this Warrant and (in the case of loss, theft or
destruction) upon delivery of an indemnity agreement (with surety if reasonably required) in an
amount reasonably satisfactory to it, or (in the case of mutilation) upon surrender and
cancellation thereof, the Company will issue, in lieu thereof, a new Warrant of like tenor.

          b. Remedies. The Company stipulates that the remedies at law of the Holder in the event of
any default by the Company in the performance of or compliance with any of the terms of this
Warrant are not and will not be adequate, and that the same may be specifically enforced.

          c. Rights Prior to Exercise. Prior to the exercise of this Warrant, the Holder shall not be
entitled to any rights of a shareholder of the Company with respect to shares for which this
Warrant shall be exercisable, including, without limitation, the right to vote, to receive
dividends or other distributions, and shall not be entitled to receive any notice of any
proceedings of the Company.

          d. Subdivision of Rights. This Warrant (as well as any new warrants issued pursuant to the
provisions of this paragraph) is exchangeable, upon the surrender hereof by the Holder, at the
principal office of the Company for any number of new warrants of like tenor and date representing
in the aggregate the right to subscribe for and purchase the number of shares of Common Stock of
the Company which may be subscribed for and purchased hereunder.

          e. Mailing of Notices, Etc. All notices and other communications from the Company to the
Holder shall be mailed by first class certified mail, postage prepaid, to the address furnished to
the Company in writing.

          f. Headings, Etc. The headings in this Warrant are for purposes of reference only, and shall
not limit or otherwise affect the meaning hereof.

          g. Change, Waiver, Etc. Neither this Warrant nor any term hereof may be changed, waived,
discharged or terminated orally but only by an instrument in writing signed by the party against
which enforcement of the change, waiver, discharge or termination is sought.

3

 

          h. Governing Law. This Warrant shall be construed and enforced in accordance with the laws of
the State of Utah.

	 	 	 	 	 
	 	ZARS, INC.

 	 
	 	By:  	 	 
	 	 	Larry D. Rigby 	 
	 	Its:  President 	 
	 

Dated: December  1 , 2003

4

 

Schedule
to Form of Common Stock Warrant

	 	 	 	 	 	 	 	 	 	 	 	 	 
	Name	 	Date	 	 	Shares	 	 	Price	 
	 
	Venture
Spark, Inc
	 	 	12/1/2003	 	 	 	1,052	 	 	$ 4.86
	Coast
Ventures
	 	 	12/1/2003	 	 	 	701	 	 	$ 4.86
	Wasatch Venture Fund II, LLC
	 	 	10/16/2003	 	 	 	20,000	 	 	$ 4.86
	 
	 	 	 	 	 	 	 	 	 	 	 	 
	 
	 	 	 	 	 	 	 	 	 	 	 
	 
	 	Total	 	 	21,753exv4w4

 

Exhibit 4.4

WARRANT

THE WARRANT EVIDENCED HEREBY AND THE COMMON STOCK ISSUABLE UPON EXERCISE HEREOF ARE SUBJECT TO
A SHAREHOLDER AGREEMENT BY AND AMONG ZARS, INC. AND THE SHAREHOLDERS OF ZARS, INC.

THIS WARRANT AND THE COMMON STOCK ISSUABLE UPON EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE
SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), AND MAY NOT BE TRANSFERRED EXCEPT PURSUANT TO AN
EFFECTIVE REGISTRATION UNDER THE ACT OR IN A TRANSACTION WHICH, IN THE OPINION OF COUNSEL
REASONABLY SATISFACTORY TO ZARS, INC., QUALIFIES AS AN EXEMPT TRANSACTION UNDER THE ACT AND THE
RULES AND REGULATIONS PROMULGATED THEREUNDER.

ZARS, INC.

Stock Purchase Warrant

     ZARS, Inc., a Utah corporation, and any successors thereto (the “Company”), hereby certifies
that, for value received, Zions First National Bank, or assigns (the “Holder”), is entitled to
purchase from the Company, subject to the terms set forth below, at the price of Nine AND 20/100ths
Dollars ($9.20) per share (the “Exercise Price”), up to Eleven Thousand Seven Hundred (11,700)
shares of the Company’s voting common stock, par value $0.12 (the “Warrant Stock”). This Warrant
is herein called the “Warrant,” and is issued under and in accordance with a Loan Agreement of even
date herewith (the “Loan Agreement”), between the Company and Zions.

     It is anticipated that the Company will participate in a reverse merger with Zars Pharma,
Inc., a Delaware corporation (the “Surviving Company”), whereby the Company will merge with and
become part of the Surviving Company (the “Merger”).

          1. Shares of Common Stock. This Warrant shall, when exercised pursuant to the terms
hereof, entitle the Holder to purchase 11,700 share of the Company’s voting stock (the “Common
Stock”) as adjusted as provided herein, which, as of the date of the Loan Agreement, represents
0.1% of the total issued and outstanding Common Stock on a fully diluted basis (the “Stock
Percentage”).

          2. Purchase Rights. If at any time the Company grants, issues or sells any options,
convertible securities or rights to purchase stock, warrants, securities or other property pro rata
to the record holders of the Common Stock for which no adjustment is made pursuant to Section 10
hereof (the “Purchase Rights”), then upon exercise of this Warrant, the Company shall grant, issue
or sell (as the case may be) to the Holder the aggregate Purchase

 

 

Rights which such Holder would have acquired if such Holder had held the number of shares of
Warrant Stock acquired upon such exercise of this Warrant immediately before the date on which a
record is taken for the grant, issuance or sale of such Purchase Rights or, if no such record is
taken, the date as of which the record holders of the Common Stock are to be determined for the
grant, issue or sale of such Purchase Rights.

          3. Exercise of Warrant. The purchase rights evidenced by this Warrant shall be
exercised by the Holder surrendering this Warrant, with the form of subscription at the end hereof
duly executed by such holder, to the Company at its offices at 1455 West 2200 South, Suite 300,
Salt Lake City, Utah or such other location as the parties may agree, accompanied by payment, in
cash, by certified or official bank check or by wire transfer of an amount equal to the Exercise
Price multiplied by the number of shares being purchased pursuant to such exercise of the Warrant.
This Warrant may be exercised for less than the full number of shares of Warrant Stock, in which
case the number of shares receivable upon the exercise of this Warrant as a whole, and the sum
payable upon the exercise of this Warrant as a whole, shall be proportionately reduced. Upon any
such partial exercise, the Company at its expense will forthwith issue to the Holder a new Warrant
or Warrants of like tenor calling for the number of shares of Warrant Stock as to which rights have
not been exercised, such Warrant or Warrants to be issued in the name of the Holder.

          4. Delivery of Stock Certificates on Exercise. As soon as practicable after the
exercise of this Warrant and payment of the Exercise Price, and in any event within ten (10) days
thereafter, the Company, at its expense, will cause to be issued in the name of and delivered to
the Holder hereof a certificate or certificates for the number of fully paid and non-assessable
shares to which such Holder shall be entitled upon such exercise. The Company agrees that the
shares so purchased shall be deemed to be issued to the Holder hereof as the record owner of such
shares as of the close of business on the date on which this Warrant shall have been surrendered
and payment made for such shares as aforesaid.

          5. Exercise Date and Term of Warrant. Holder shall have from the Date of this Warrant
until June 30, 2017, in which to exercise this Warrant, at which time all of the Holder’s rights
hereunder shall terminate.

          6. Shareholder Agreement. Upon exercise of this Warrant and at the request of the
Company, the Holder shall execute and deliver to the Company a Shareholder Agreement or Statement
of Acceptance thereof prior to the transfer or delivery of any shares and prior to the expiration
of the Exercise Period. The Company shall have no obligation to transfer or deliver the shares
issued pursuant to this Warrant unless or until the Holder executes and delivers the foregoing to
the Company.

          7. No Impairment. The Company will not, by amendment of its articles of incorporation
or through reorganization, consolidation, merger, dissolution, sale of assets or any other
voluntary action, avoid or seek to avoid the observance or performance of any of the terms of this
Warrant, but will at all times in good faith assist in the carrying out of all

2

 

such terms and in the taking of all such action as may be necessary or appropriate in order to
protect the rights of the Holder against impairment. Without limiting the generality of the
foregoing, the Company will not increase the par value of any shares of stock receivable upon the
exercise of this Warrant above the amount payable therefor upon such exercise, and at all times
will take all such action as may be necessary or appropriate in order that the Company may validly
and legally issue fully paid and non-assessable stock upon the exercise of this Warrant and all
other Warrants at the time outstanding.

          8. Reservation of Stock, Etc., Issuable on Exercise of Warrants. The Company shall at
all times reserve and keep available out of its authorized but unissued stock, solely for the
issuance and delivery upon the exercise of this Warrant and other similar Warrants, such number of
its duly authorized shares of Common Stock as from time to time shall be issuable upon the exercise
of this Warrant, and all other Warrants at the time outstanding.

          9. Registration Rights. The Company agrees to use its best efforts to amend the
Second Amended and Restated Registration Rights Agreement, dated as of August 30, 2004 (the
“Registration Rights Agreement”) to provide that the Warrant Stock shall have the registration
rights, and be deemed “Registrable Securities,” pursuant to and as set forth in the Registration
Rights Agreement.

	 	10.	 	Adjustment upon Change in Capitalization, Payment of Stock
Dividend, Merger, Consolidation or Other Business Combination.

               10.1. Change in Capitalization; Stock Dividend. In case, prior to the expiration of
this Warrant by exercise or by its terms, the Company shall issue any shares of its stock as a
share dividend or subdivide the number of outstanding shares of stock into a greater number of
shares, then, in either of such cases, the Exercise Price per share of the stock purchasable
pursuant to this Warrant in effect at the time of such action shall be proportionately reduced and
the number of shares at the time purchasable pursuant to this Warrant shall be proportionately
increased; and conversely, in the event the Company shall contract the number of outstanding shares
of stock by combining such shares into a smaller number of shares, then, in such case, the Exercise
Price per share of the stock purchasable pursuant to this Warrant in effect at the time of such
action shall be proportionately increased and the number of shares at that time purchasable
pursuant to this Warrant shall be proportionately decreased. If the Company shall, at any time
during the life of this Warrant, declare a dividend payable in cash on its stock and shall at
substantially the same time offer to its shareholders a right to purchase new shares of stock from
the proceeds of such dividend or for an amount substantially equal to the dividend, all shares of
stock so issued shall, for the purpose of this Warrant, be deemed to have been issued as a share
dividend. Any dividend paid or distributed upon the stock in shares of any other class or
securities convertible into stock shall be treated as a dividend paid in shares of stock to the
extent that shares of stock are issuable upon the conversion thereof.

3

 

               10.2. Organic Change. Any recapitalization, reorganization, reclassification,
consolidation, merger, sale of all or substantially all of the Company’s assets or other
transaction which is effected in such a way holders of stock are entitled to receive (either
directly or upon subsequent liquidation) stock, securities or assets with respect to or in exchange
for stock is referred to herein as an “Organic Change”. Prior to the consummation of any Organic
Change, the Company shall make appropriate provision to ensure that any successor entity shall
assume the obligations of this Warrant, and this Warrant shall be exercisable for the same
securities, cash, and property as would be payable for the Warrant Stock issuable upon exercise of
the unexercised portion of this Warrant as if such Warrant Stock were outstanding on the record
date for the Organic Change and subsequent closing. The Exercise Price per share of the stock
purchasable pursuant to this Warrant in effect at the time of such action and the number of shares
at the time purchasable pursuant to this Warrant shall be adjusted accordingly. The Company shall
not effect any such Organic Change unless, prior to the consummation thereof, the successor entity
(if other than the Company) resulting from such Organic Change (including a purchaser of all or
substantially all of the Company’s assets) assumes by written instrument the obligation to deliver
to each Holder such shares of stock, securities or assets as, in accordance with the foregoing
provisions, such Holder may be entitled to acquire upon exercise of Warrants.

               10.3. Zars Pharma Merger. Both the Company and the Surviving Company hereby expressly
covenant and warrant, (a) that this Warrant shall survive the Merger, (b) that, upon the Merger,
the Holder’s right to purchase the number of shares of the Company as to which this Warrant remains
unexercised shall become the Holder’s right to purchase shares of the Surviving Company subject to
any adjustment pursuant to this Section 10, and (c) that, upon the Merger, the Surviving Company
expressly assumes the obligations of the Company hereunder.

               10.4. Certain Events. If any event occurs of the type contemplated by the provisions
of this Section 10 but not expressly provided for by such provisions (including, without
limitation, the granting of stock appreciation rights, phantom stock rights or other rights with
equity features but excluding any Permitted Issuance), then the Company’s Board of Directors shall
exercise their reasonable judgment consistent with the fundamental intent of such provisions in
making an appropriate adjustment in the Exercise Price and the number of Warrant Shares obtainable
upon exercise of this Warrant so as to protect the rights of the Holder of this Warrant.

               10.5. Dividend Record Date. In case:

                    (i) the Company shall take a record of its shareholders for the purpose of entitling the
holders of its stock to receive a dividend payable otherwise than in cash, or any other
distribution in respect of the stock (including cash), pursuant to, without limitation, any
spin-off, split-off, or distribution of the Company’s assets; or

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                    (ii) the Company shall take a record of its shareholders for the purpose of entitling the
holders of its stock to subscribe for or purchase any shares of any class or to receive any other
rights; or

                    (iii) of any classification, reclassification, or other reorganization of the shares which the
Company is authorized to issue, consolidation or merger of the Company with or into another
corporation, or conveyance of all or substantially all of the assets of the Company; or

                    (iv) of the voluntary or involuntary dissolution, liquidation, or winding up of the Company;

then, and in any such case, the Company shall mail to Zions or the Holder, as the case may be, at
least 30 days prior thereto, a notice stating the date or expected date on which a record is to be
taken for the purpose of such dividend, distribution, or rights, or the date on which such
classification, reclassification, reorganization, consolidation, merger, conveyance, dissolution,
liquidation, or winding up is to take place, as the case may be. Such notice shall also specify
the date or expected date, if any is to be fixed, as of which holders of record of stock shall be
entitled to participate in such dividend, distribution, or rights, or shall be entitled to exchange
their stock for securities or other property deliverable upon such classification,
reclassification, reorganization, consolidation, merger, conveyance, dissolution, liquidation, or
winding up, as the case may be.

               10.6. Liquidation. If the Company at any time while this Warrant shall remain
unexpired and unexercised shall sell all or substantially all of its property or dissolve,
liquidate, or wind up its affairs, Zions or the Holder, as the case may be, may thereafter receive
upon exercise hereof, in lieu of each share of stock of the Company which it would have been
entitled to receive, the same kind and amount of any securities or assets as may be issuable,
distributable, or payable upon any such sale, dissolution, liquidation, or winding up with respect
to each share of stock of the Company.

          11. Stock. All shares of stock issuable by the Company upon the exercise of the
Warrant shall be validly issued, fully paid and non-assessable, and the Company shall pay all taxes
and other governmental charges that may be imposed under the laws of the United States of America
or of any State or any political subdivision or taxing authority of the United States of America or
of any State in respect of the issue or delivery thereof or of other securities deliverable upon
exercise of warrants. The Company shall not be required, however, to pay any tax or other charge
imposed in connection with any transfer involved in the issue of any certificate for shares of
stock or other securities to any person or party other than the Holder of the Warrant as and when
exercised, and in such case the Company shall not be required to issue or deliver any stock
certificate until such tax or other charge has been paid or it has been established to the
Company’s satisfaction that no tax or other charge is due.

5

 

          12. Transfer. Subject to the provisions of applicable federal and state securities
laws and to receipt by the Company of a reasonably satisfactory and customary opinion of Zions’
counsel to the effect that such transfer is not subject to the registration requirements of federal
or applicable state securities laws, this Warrant Certificate and all rights hereunder are
transferable by any holder hereof in whole or in part, on the records of the Company, upon
surrender of this Warrant Certificate duly endorsed, or accompanied by a written instrument of
transfer in form satisfactory to the Company, duly executed by the holder hereof or his attorney
duly authorized in writing, and upon payment of any necessary transfer tax or other governmental
charge imposed upon such transfer. Upon any partial transfer the Company will issue and deliver to
such holder a new Warrant Certificate or Certificates with respect to any portion not so
transferred. Each taker and holder of this Warrant Certificate, by taking or holding the same,
consents and agrees that this Warrant Certificate when duly endorsed in blank shall be deemed
negotiable and that when this Warrant Certificate shall have been so endorsed, the holder hereof
may be treated by the Company and all other persons dealing with this Warrant Certificate as the
absolute owner hereof for any purpose and as the person entitled to exercise the rights represented
hereby, or to the transfer hereof in the records of the Company, any notice to the contrary
notwithstanding, but until such transfer on such records, the Company may treat the registered
holder hereof as the owner for all purposes.

          13. Transfer of the Warrant. Zions shall be permitted to disclose to any party to
which it proposes to transfer the Warrant such financial and other information as Zions has or may
have in its possession regarding the Company and its subsidiaries, including without limitation any
financial and other information provided to Zions in its capacity as lender to and creditor of the
Company and of the Company’s subsidiaries, and including without limitation financial and other
information provided to Zions pursuant to the provisions of the Loan Agreement; provided that the
party to which such information is disclosed shall have agreed in advance in writing for the
benefit of the Company to receive and hold such information confidentially.

          14. Assignment or Transfer Prohibited. The benefit of this Warrant Certificate and of
the Warrant represented hereby may not be assigned or in any other manner transferred and the
obligations may not be delegated, except by Zions and assigns as provided herein. Subject to the
foregoing limitation upon assignment and delegation, this Warrant Certificate shall be binding upon
and inure to the benefit of the parties and their respective legal representatives, successors,
agents, heirs, and assigns.

          15. Miscellaneous.

               a. Qualified Institutional Buyer. Zions represents to the Company that it is a
“qualified institutional buyer” within the meaning of Rule 144A promulgated under the Securities
Act of 1933, as amended.

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               b. Replacement of Warrant. Upon receipt of evidence reasonably satisfactory to the
Company of the loss, theft, destruction or mutilation of this Warrant and (in the case of loss,
theft or destruction) upon delivery of an indemnity agreement (with surety if reasonably required)
in an amount reasonably satisfactory to it, or (in the case of mutilation) upon surrender and
cancellation thereof, the Company will issue, in lieu thereof, a new Warrant of like tenor.

               c. Enforcement. In the event of a dispute between the parties arising under this
Warrant Certificate, the party prevailing in such dispute shall be entitled to collect such party’s
costs from the other party, including without limitation court costs and reasonable attorney’s
fees.

               d. Remedies. The Company stipulates that the remedies at law of the Holder in the
event of any default by the Company in the performance of or compliance with any of the terms of
this Warrant are not and will not be adequate, and that the same may be specifically enforced.

               e. Rights Prior to Exercise. Prior to the exercise of this Warrant, the Holder shall
not be entitled to any rights of a shareholder of the Company with respect to shares for which this
Warrant shall be exercisable, including, without limitation, the right to vote, to receive
dividends or other distributions.

               f. Subdivision of Rights. This Warrant (as well as any new warrants issued pursuant
to the provisions of this paragraph) is exchangeable, upon the surrender hereof by the Holder, at
the principal office of the Company for any number of new warrants of like tenor and date
representing in the aggregate the right to subscribe for and purchase the number of shares of
Common Stock of the Company which may be subscribed for and purchased hereunder.

               g. Mailing of Notices, Etc. All notices and other communications from the Company to
the Holder shall be mailed by first-class certified mail, postage prepaid, to the address furnished
to the Company in writing.

               h. Headings, Etc. The headings in this Warrant are for purposes of reference only,
and shall not limit or otherwise affect the meaning hereof.

               i. Change, Waiver, Etc. Neither this Warrant nor any term hereof may be changed,
waived, discharged or terminated orally but only by an instrument in writing signed by the party
against which enforcement of the change, waiver, discharge or termination is sought.

               j. Governing Law. This Warrant shall be construed and enforced in accordance with the
laws of the State of Utah.

7

 

               k. Severability. In the event any one or more of the provisions contained in this
Warrant Certificate shall for any reason be held to be invalid, illegal or unenforceable in any
respect, such invalidity, illegality or unenforceability shall not affect the validity of any other
provision hereof and this Warrant Certificate shall be construed as if such invalid, illegal or
unenforceable provision were not contained herein; provided that the Warrant Certificate as so
modified preserves the basic intent of the parties.

               l. Entire Agreement. This Warrant Certificate and any exhibits and schedules attached
hereto, together with the Loan Agreement and related loan documents, constitute the entire
agreement between the parties hereto with respect to the subject matter contained herein, and there
are no covenants, terms or conditions, express or implied, other than as set forth or referred to
herein. This Warrant Certificate supersedes all prior agreements between the parties hereto
relating to all or part of the subject matter herein. No representations, oral or written,
modifying or contradicting the terms of this Warrant Certificate have been made by any party except
as contained herein. This Warrant Certificate may not be amended, modified or canceled except as
provided herein or by written agreement of the parties signed by the party against whom enforcement
is sought.

	 	 	 	 	 	 	 
	 	 	ZARS, INC., a Utah corporation	 	 
	 
	 	 	 	 	 	 
	 

	 	By:
	 	/s/ Robert Lippert	 	 
	 

	 	 	 	 	 	 
	 	 	Name: Robert Lippert	 	 
	 	 	Title: CEO	 	 
	 
	 	 	 	 	 	 
	 	 	ZARS PHARMA, INC., a Delaware corporation	 	 
	 
	 

	 	By:
	 	/s/ Robert Lippert	 	 
	 

	 	 	 	 	 	 
	 	 	Name: Robert Lippert	 	 
	 	 	Title: CEO	 	 

Dated: June 30, 2007

8

 

[To be signed only upon exercise of Warrant]

To ZARS, Inc.

     The undersigned, the holder of the within Warrant, hereby irrevocably elects to exercise the
purchase right represented by such Warrant for, and to purchase thereunder,                      shares of Common
Stock of ZARS, Inc. and herewith makes payment of $                     therefor, and requests that the
certificates for such shares be issued in the name of, and be delivered to the undersigned, whose
address is                     .

Dated:

	 	 	 
	 

	 	 
	 
	 	 
	 

	 	 
	 

	 	(Signature must conform in all respects to name of
Holder as specified on the face of the Warrant)
	 
	 	 
	 

	 	 
	 

	 	Address

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