Document:

Exhibit 4.1

COMMON STOCK PURCHASE WARRANT

NEITHER THIS SECURITY NOR THE SECURITIES INTO WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR PURSUANT TO AN AVAILABLE EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT AND IN ACCORDANCE WITH APPLICABLE STATE SECURITIES LAWS AS EVIDENCED BY A LEGAL OPINION OF COUNSEL TO THE TRANSFEROR REASONABLY ACCEPTABLE TO THE COMPANY TO SUCH EFFECT, THE SUBSTANCE OF WHICH SHALL BE REASONABLY ACCEPTABLE TO THE COMPANY.  

COMMON STOCK PURCHASE WARRANT

To Purchase  Shares of Common Stock of

Large Scale Biology Corporation 

                              THIS COMMON STOCK PURCHASE WARRANT (the “Warrant”) CERTIFIES that, for value received, Kentucky Technology, Inc. a Kentucky Corporation (the “Holder”), is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the earlier of: (a) July 31, 2006 or (b) the forty-fifth (45th) calendar day following the Prepayment Date under the Loan Agreement (the “Initial Exercise Date”) and on or prior to December 17, 20111 (the “Termination Date”) but not thereafter, to subscribe for and purchase from Large Scale Biology Corporation, a Delaware corporation (the “Company”), up to the Number of Shares (as defined below, and
herein referred to as the “Warrant Shares”) of Common Stock, par value $0.001 per share, of the Company (the “Common Stock”).  The purchase price of each share of Common Stock (the “Exercise Price”) under this Warrant shall be $1.42
2,subject to adjustment hereunder.  The Exercise Price and the number of Warrant Shares for which the Warrant is exercisable shall be subject to adjustment as provided herein. Capitalized terms used and not otherwise defined herein shall have the meanings set forth in that certain Loan Agreement dated as of December 17, 2004 (the “Loan Agreement”), among the Company and Holder.

                              1.     Number of Shares Issuable Under the Warrant.  For purposes of this Warrant, the “Number of Shares” at any time is determined according to the following formula:

                              Number of Shares3= (Multiplier x Aggregate Daily Principal Balance) – Shares Issued 

where, 

“Multiplier” means .00045659178 (as adjusted in accordance with the terms of this Warrant);

“Aggregate Daily Principal Balance” means the sum of each Daily Balance for the number of days during which a principal balance is outstanding under the Loan Agreement; 

	
  

  
	
  
1 The seventh anniversary   of the Closing Date of the Loan Agreement.
  
	
  
2 125% of the daily volume   weighted average price of the Company’s Common Stock for the 5 consecutive   days  immediately prior to the Closing   Date of the Loan Agreement.
  
	
  
3 For example, assuming $1   Million is advanced on December 17, 2004 and an additional $1.9 Million is   advanced on January 14, 2005 and no payments of principal are made until   December 16, 2005 when the entire principal balance is paid off, then the   aggregate Number of Shares that may be purchased by exercise of this warrant   would be 459,012 shares calculated as follows:
  

.00045659178 x ($1 Million balance x 28 days outstanding + $2.9 Million balance x 337 days outstanding) = 459,012 shares

“Daily Balance” means the principal balance outstanding on each day under the Loan Agreement; and

“Shares Issued” means the number of Warrant Shares previously issued (as adjusted in accordance with the terms of this Warrant) pursuant to the foregoing calculation at the time this Warrant is exercised.

Notwithstanding the foregoing, the maximum Number of Shares is 700,000.

                              2.     Title to Warrant.  After the Initial Exercise Date and subject to compliance with applicable laws and Section 8 of this Warrant, this Warrant and all rights hereunder are transferable, in whole or in part, at the office or agency of the Company by the Holder in person or by duly authorized attorney, upon surrender of this Warrant together with the Assignment Form annexed hereto properly endorsed.  The transferee shall sign an investment letter in form and substance reasonably satisfactory to the Company.

                              3.     Authorization of Shares.  The Company covenants that all Warrant Shares which may be issued upon the exercise of the purchase rights represented by this Warrant will, upon exercise of the purchase rights represented by this Warrant, be duly authorized, validly issued, fully paid and nonassessable and free from all taxes, liens and charges in respect of the issue thereof (other than taxes in respect of any transfer occurring contemporaneously with such issue).

                              4.     Exercise of Warrant.

                              (a)          Exercise of the purchase rights represented by this Warrant may be made at any time or times on or after the Initial Exercise Date and on or before the Termination Date by delivery to the Company of: (a) a duly executed facsimile copy of the Notice of Exercise Form annexed hereto (or such other office or agency of the Company as it may designate by notice in writing to the registered Holder at the address of such Holder appearing on the books of the Company); (b) this Warrant; and (c) the aggregate Exercise Price of the Warrant Shares thereby purchased by wire transfer or cashier’s check drawn on a United States bank.  The Company shall endeavor to delivery certificates for shares purchased hereunder to the
Holder within 5 business days from the date of exercise of this Warrant.  This Warrant shall be deemed to have been exercised, the Warrant Shares shall be deemed to have been issued, and Holder or any other person so properly designated to be named therein shall be deemed to have become a holder of record of such shares for all purposes, as of 5:00 p.m. Pacific Time on the last date on which all of the deliverables specified above have been received by the Company. 

                              (b)          If this Warrant shall have been exercised in part, the Company shall, at the time of delivery of the certificate or certificates representing Warrant Shares, deliver to Holder a new Warrant evidencing the rights of Holder to purchase the unpurchased Warrant Shares called for by this Warrant, which new Warrant shall in all other respects be identical with this Warrant.

                              5.     No Fractional Shares or Scrip.  No fractional shares or scrip representing fractional shares shall be issued upon the exercise of this Warrant.  As to any fraction of a share which Holder would otherwise be entitled to purchase upon such exercise, the Company shall pay a cash adjustment in respect of such final fraction in an amount equal to such fraction multiplied by the Exercise Price.

                              6.     Charges, Taxes and Expenses.  Issuance of certificates for Warrant Shares shall be made without charge to the Holder for any issue or transfer tax in respect of the issuance of such certificate, all of which taxes shall be paid by the Company, and such certificates shall be issued in the name of the Holder or in such name or names as may be directed by the Holder; provided, however, that in the event certificates for Warrant Shares are to be issued in a name other than the name of the Holder, this Warrant when surrendered for exercise shall be accompanied by the Assignment Form attached hereto duly executed by the Holder; and the Company may require, as a condition thereto, the payment of a sum sufficient to reimburse it for
any transfer tax incidental thereto.

                              7.     Closing of Books.  The Company will not close its stockholder books or records in any manner that prevents the timely exercise of this Warrant, pursuant to the terms hereof.

                              8.     Transfer, Division and Combination.

                              (a)                    This Warrant and all rights hereunder may not be transferred in whole or in part prior to July 31, 2006 or the forty-fifth (45th) calendar day following the Prepayment Date as defined in the Loan Agreement without the prior written consent of the Company, except for a transfer to the University of Kentucky Research Foundation, and any such attempted transfer without the Company’s consent shall be null and void.  Subject to compliance with any applicable securities laws and the conditions set forth in Sections 2 and 8(e) hereof, this Warrant and all rights hereunder are transferable, in whole or in part, upon surrender of this Warrant at the
principal office of the Company, together with a written assignment of this Warrant substantially in the form attached hereto duly executed by the Holder or its agent or attorney and funds sufficient to pay any transfer taxes payable upon the making of such transfer.  Upon such surrender and, if required, such payment, the Company shall execute and deliver a new Warrant or Warrants in the name of the assignee or assignees and in the denomination or denominations specified in such instrument of assignment, and shall issue to the assignor a new Warrant evidencing the portion of this Warrant not so assigned, and this Warrant shall promptly be cancelled.  A Warrant, if properly assigned, may be exercised by a new holder for the purchase of Warrant Shares without having a new Warrant issued.

                              (b)                    This Warrant may be divided or combined with other Warrants upon presentation hereof at the aforesaid office of the Company, together with a written notice specifying the names and denominations in which new Warrants are to be issued, signed by the Holder or its agent or attorney.  Subject to compliance with Section 8(a), as to any transfer which may be involved in such division or combination, the Company shall execute and deliver a new Warrant or Warrants in exchange for the Warrant or Warrants to be divided or combined in accordance with such notice.

                              (c)                    The Company shall prepare, issue and deliver at its own expense (other than transfer taxes) the new Warrant or Warrants under this Section 8.

                              (d)                    The Company agrees to maintain, at its aforesaid office, books for the registration and the registration of transfer of the Warrants.

                              (e)                    If, at the time of the surrender of this Warrant in connection with any transfer of this Warrant, the transfer of this Warrant shall not be registered pursuant to an effective registration statement under the Securities Act and under applicable state securities or blue sky laws, the Company may require, as a condition of allowing such transfer: (i) that the Holder or transferee of this Warrant, as the case may be, furnish to the Company a written opinion of counsel (which opinion shall be in form, substance and scope customary for opinions of counsel in comparable transactions) to the effect that such transfer may be made without registration under the Securities Act
and under applicable state securities or blue sky laws, (ii) that the holder or transferee execute and deliver to the Company an investment letter in form and substance acceptable to the Company and (iii) that the transferee be an “accredited investor” as defined in Rule 501(a)(1), (a)(2), (a)(3), (a)(7), or (a)(8) promulgated under the Securities Act or a qualified institutional buyer as defined in Rule 144A(a) under the Securities Act.

                              9.     No Rights as Shareholder until Exercise.  This Warrant does not entitle the Holder to any voting rights or other rights as a shareholder of the Company prior to the exercise hereof.  Upon the surrender of this Warrant and the payment of the aggregate Exercise Price, the Warrant Shares so purchased shall be and be deemed to be issued to such Holder as the record owner of such shares as of the close of business on the later of the date of such surrender or payment.

                              10.     Loss, Theft, Destruction or Mutilation of Warrant.  The Company covenants that upon receipt by the Company of evidence reasonably satisfactory to it of the loss, theft, destruction or mutilation of this Warrant or any stock certificate relating to the Warrant Shares, and in case of loss, theft or destruction, of indemnity or security reasonably satisfactory to it (which, in the case of the Warrant, shall not include the posting of any bond), and upon surrender and cancellation of such Warrant or stock certificate, if mutilated, the Company will make and deliver a new Warrant or stock certificate of like tenor and dated as of such cancellation, in lieu of such Warrant or stock certificate.

                              11.     Saturdays, Sundays, Holidays, etc.  If the last or appointed day for the taking of any action or the expiration of any right required or granted herein shall be a Saturday, Sunday or a legal holiday, then such action may be taken or such right may be exercised on the next succeeding day not a Saturday, Sunday or legal holiday.

                              12.     Adjustments of Exercise Price and Number of Shares.  The number and kind of securities purchasable upon the exercise of this Warrant and the Exercise Price shall be subject to adjustment from time to time upon the happening of any of the following.  In case the Company shall (i) pay a dividend in shares of Common Stock or make a distribution in shares of Common Stock to holders of its outstanding Common Stock, (ii) subdivide its outstanding shares of Common Stock into a greater number of shares, (iii) combine its outstanding shares of Common Stock into a smaller number of shares of Common Stock, or (iv) issue any shares of its capital stock in a reclassification of the Common Stock, then the number of Warrant Shares purchasable upon
exercise of this Warrant immediately prior thereto shall be adjusted so that the Holder shall be entitled to receive the kind and number of Warrant Shares or other securities of the Company which it would have owned or have been entitled to receive had such Warrant been exercised in advance thereof.  Upon each such adjustment of the kind and number of Warrant Shares or other securities of the Company which are purchasable hereunder, the Holder shall thereafter be entitled to purchase the number of Warrant Shares or other securities resulting from such adjustment at an Exercise Price per Warrant Share or other security obtained by multiplying the Exercise Price in effect immediately prior to such adjustment by the number of Warrant Shares purchasable pursuant hereto immediately prior to such adjustment and dividing by the number of Warrant Shares or other securities of the Company that are purchasable pursuant hereto immediately after such adjustment.  An adjustment made pursuant to this
paragraph shall become effective immediately after the effective date of such event retroactive to the record date, if any, for such event.

                              13.     Reorganization, Reclassification, Merger, Consolidation or Disposition of Assets.  In case the Company shall reorganize its capital, reclassify its capital stock, consolidate or merge with or into another corporation (where the Company is not the surviving corporation or where there is a change in or distribution with respect to the Common Stock of the Company), or sell, transfer or otherwise dispose of its property, assets or business to another corporation and, pursuant to the terms of such reorganization, reclassification, merger, consolidation or disposition of assets, shares of common stock of the successor or acquiring corporation, or any cash, shares of stock or other securities or property of any nature whatsoever (including
warrants or other subscription or purchase rights) in addition to or in lieu of common stock of the successor or acquiring corporation (“Other Property”), are to be received by or distributed to the holders of Common Stock of the Company, then the Holder shall have the right thereafter to receive upon exercise of this Warrant, the number of shares of Common Stock of the successor or acquiring corporation or of the Company, if it is the surviving corporation, and Other Property receivable upon or as a result of such reorganization, reclassification, merger, consolidation or disposition of assets by a Holder of the number of shares of Common Stock for which this Warrant is exercisable immediately prior to such event.  In case of any such reorganization, reclassification, merger, consolidation or disposition of assets, the successor or acquiring corporation (if other than the Company) shall expressly assume the due and punctual observance and performance of each and every covenant
and condition of this Warrant to be performed and observed by the Company and all the obligations and liabilities hereunder, subject to such modifications as may be deemed appropriate (as determined in good faith by resolution of the Board of Directors of the Company) in order to provide for adjustments of Warrant Shares for which this Warrant is exercisable which shall be as nearly equivalent as practicable to the adjustments provided for in this Section 13.  For purposes of this Section 13, “common stock of the successor or acquiring corporation” shall include stock of such corporation of any class which is not preferred as to dividends or assets over any other class of stock of such corporation and which is not subject to redemption and shall also include any evidences of indebtedness, shares of stock or other securities which are convertible into or exchangeable for any such stock, either immediately or upon the arrival of a specified date or the happening of a specified event and
any warrants or other rights to subscribe for or purchase any such stock.  The foregoing provisions of this Section 13 shall similarly apply to successive reorganizations, reclassifications, mergers, consolidations or disposition of assets. 

                              14.     Voluntary Adjustment by the Company.  The Company may at any time during the term of this Warrant reduce the then current Exercise Price to any amount and for any period of time deemed appropriate by the Board of Directors of the Company.

                              15.     Notice of Adjustment.  Whenever the number of Warrant Shares or number or kind of securities or other property purchasable upon the exercise of this Warrant or the Exercise Price is adjusted, as herein provided, the Company shall give notice thereof to the Holder, which notice shall state the number of Warrant Shares (and other securities or property) purchasable upon the exercise of this Warrant and the Exercise Price of such Warrant Shares (and other securities or property) after such adjustment, setting forth a brief statement of the facts requiring such adjustment and setting forth the computation by which such adjustment was made.

                              16.     Notice of Corporate Action.  If at any time:

                              (a)          the Company shall take a record of the holders of its Common Stock for the purpose of entitling them to receive a dividend or other distribution, or any right to subscribe for or purchase any evidences of its indebtedness, any shares of stock of any class or any other securities or property, or to receive any other right, or

                              (b)          there shall be any capital reorganization of the Company, any reclassification or recapitalization of the capital stock of the Company or any consolidation or merger of the Company with, or any sale, transfer or other disposition of all or substantially all the property, assets or business of the Company to, another corporation or,

                              (c)          there shall be a voluntary or involuntary dissolution, liquidation or winding up of the Company; then, in any one or more of such cases, the Company shall give to Holder (i) at least 10 days’ prior written notice of the date on which a record date shall be selected for such dividend, distribution or right or for determining rights to vote in respect of any such reorganization, reclassification, merger, consolidation, sale, transfer, disposition, liquidation or winding up, and (ii) in the case of any such reorganization, reclassification, merger, consolidation, sale, transfer, disposition, dissolution, liquidation or winding up, at least 10 days’ prior written notice of the date when the same shall take place. 
Such notice in accordance with the foregoing clause also shall specify (i) the date on which any such record is to be taken for the purpose of such dividend, distribution or right, the date on which the holders of Common Stock shall be entitled to any such dividend, distribution or right, and the amount and character thereof, and (ii) the date on which any such reorganization, reclassification, merger, consolidation, sale, transfer, disposition, dissolution, liquidation or winding up is to take place and the time, if any such time is to be fixed, as of which the holders of Common Stock shall be entitled to exchange their Warrant Shares for securities or other property deliverable upon such disposition, dissolution, liquidation or winding up.  Each such written notice shall be sufficiently given if addressed to Holder at the last address of Holder appearing on the books of the Company and delivered in accordance with Section 19(d).

                              17.     Authorized Shares.  The Company covenants that during the period the Warrant is outstanding, it will reserve from its authorized and unissued Common Stock a sufficient number of shares to provide for the issuance of the Warrant Shares upon the exercise of any purchase rights under this Warrant.  The Company further covenants that its issuance of this Warrant shall constitute full authority to its officers who are charged with the duty of executing stock certificates to execute and issue the necessary certificates for the Warrant Shares upon the exercise of the purchase rights under this Warrant.  The Company will take all such reasonable action as may be necessary to assure that such Warrant Shares may be issued as provided herein
without violation of any applicable law or regulation.

                              Except and to the extent as waived or consented to by the Holder, the Company shall not by any action, including, without limitation, amending its certificate of incorporation or through any reorganization, transfer of assets, consolidation, merger, dissolution, issue or sale of securities or any other voluntary action, avoid or seek to avoid the observance or performance of any of the terms of this Warrant, but will at all times in good faith assist in the carrying out of all such terms and in the taking of all such actions as may be necessary or appropriate to protect the rights of Holder as set forth in this Warrant against impairment.  Without limiting the generality of the foregoing, the Company will (a) not increase the par value of any Warrant Shares above the amount payable
therefor upon such exercise immediately prior to such increase in par value, (b) take all such action as may be necessary or appropriate in order that the Company may validly and legally issue fully paid and nonassessable Warrant Shares upon the exercise of this Warrant, and (c) use commercially reasonable efforts to obtain all such authorizations, exemptions or consents from any public regulatory body having jurisdiction thereof as may be necessary to enable the Company to perform its obligations under this Warrant.

                              Before taking any action which would result in an adjustment in the number of Warrant Shares for which this Warrant is exercisable or in the Exercise Price, the Company shall obtain all such authorizations or exemptions thereof, or consents thereto, as may be necessary from any public regulatory body or bodies having jurisdiction thereof.

                              18.     Holder’s Securities Law Representations and Warranties.  Holder hereby represents and warrants as follows:

                                                  (a)          Investment Intent.  Holder understands that this Warrant and the Warrant Shares issuable hereunder (the “Securities”) are “restricted securities” and have not been registered under the Securities Act or any applicable state securities law and is acquiring the Securities as principal for its own account for investment purposes only and not with a view to or for distributing or reselling such Securities or any part thereof, has no present intention of distributing any of such Securities and has no arrangement or understanding with any other persons regarding the distribution of
such Securities (this representation and warranty not limiting Holder’s right to sell the Securities pursuant to the Registration Statement or otherwise in compliance with applicable federal and state securities laws).  Holder is acquiring the Securities hereunder in the ordinary course of its business, and Holder has not been formed for the specific purpose of acquiring the Securities.  Holder does not have any agreement or understanding, directly or indirectly, with any person to distribute any of the Securities.

                                                  (b)          Holder Status.  At the time Holder was offered the Securities, it was, and at the date hereof it is, and on each date on which it exercises any Warrants, it will be either: (i) an “accredited investor” as defined in Rule 501(a)(1), (a)(2), (a)(3), (a)(7) or (a)(8) under the Securities Act or (ii) a “qualified institutional buyer” as defined in Rule 144A(a) under the Securities Act.  Holder is not required to be registered as a broker-dealer under Section 15 of the Exchange Act or any state law applicable in the context of the transactions provided for under this
Agreement.  

                                                  (c)          Experience of Holder.  Holder, either alone or together with its representatives, has such knowledge, sophistication and experience in business and financial matters so as to be capable of evaluating the merits and risks of the prospective investment in the Securities, has had an opportunity to ask questions of and receive answers to such questions from the Company, and has evaluated the merits and risks of such investment.  Holder is able to bear the economic risk of an investment in the Securities and, at the present time, is able to afford a complete loss of such investment.

                                                  (d)          General Solicitation.  Holder is not purchasing the Securities as a result of any advertisement, article, notice or other communication regarding the Securities published in any newspaper, magazine or similar media or broadcast over television or radio or presented at any seminar or any other general solicitation or general advertisement.

                              19.     Miscellaneous.

                                                  (a)          Jurisdiction.  All questions concerning the construction, validity, enforcement and interpretation of this Warrant shall be determined in accordance with the provisions of the Loan Agreement.

                                                  (b)          Restrictions.  The Holder acknowledges that the Warrant Shares acquired upon the exercise of this Warrant, if not registered, will have restrictions upon resale imposed by state and federal securities laws.

                                                  (c)          Nonwaiver and Expenses.  No course of dealing or any delay or failure to exercise any right hereunder on the part of Holder shall operate as a waiver of such right or otherwise prejudice Holder’s rights, powers or remedies, notwithstanding all rights hereunder terminate on the Termination Date.  If the Company willfully and knowingly fails to comply with any provision of this Warrant, which results in any material damages to the Holder, the Company shall pay to Holder such amounts as shall be sufficient to cover any costs and expenses including, but not limited to, reasonable attorneys’
fees, including those of appellate proceedings, incurred by Holder in collecting any amounts due pursuant hereto or in otherwise enforcing any of its rights, powers or remedies hereunder.

                                                  (d)          Notices.  Any notice, request or other document required or permitted to be given or delivered to the Holder by the Company shall be delivered in accordance with the notice provisions of the Loan Agreement.

                                                  (e)          Limitation of Liability.  No provision hereof, in the absence of any affirmative action by Holder to exercise this Warrant or purchase Warrant Shares, and no enumeration herein of the rights or privileges of Holder, shall give rise to any liability of Holder for the purchase price of any Common Stock or as a stockholder of the Company, whether such liability is asserted by the Company or by creditors of the Company.

                                                  (f)          Remedies.  Holder, in addition to being entitled to exercise all rights granted by law, including recovery of damages, will be entitled to specific performance of its rights under this Warrant.  The Company agrees that monetary damages would not be adequate compensation for any loss incurred by reason of a breach by it of the provisions of this Warrant and hereby agrees to waive the defense in any action for specific performance that a remedy at law would be adequate.

                                                  (g)          Successors and Assigns.  Subject to applicable securities laws, this Warrant and the rights and obligations evidenced hereby shall inure to the benefit of and be binding upon the successors of the Company and the successors and permitted assigns of Holder.  The provisions of this Warrant are intended to be for the benefit of all Holders from time to time of this Warrant and shall be enforceable by any such Holder or holder of Warrant Shares.

                                                  (h)          Amendment.  This Warrant may be modified or amended or the provisions hereof waived with the written consent of the Company and the Holder.

                                                  (i)          Severability.  Wherever possible, each provision of this Warrant shall be interpreted in such manner as to be effective and valid under applicable law, but if any provision of this Warrant shall be prohibited by or invalid under applicable law, such provision shall be ineffective to the extent of such prohibition or invalidity, without invalidating the remainder of such provisions or the remaining provisions of this Warrant.

                                                  (j)          Headings.  The headings used in this Warrant are for the convenience of reference only and shall not, for any purpose, be deemed a part of this Warrant.

[The balance of this page intentionally left blank]

                              IN WITNESS WHEREOF, the Company has caused this Warrant to be executed by its officer thereunto duly authorized.

	
  
 
  	
  
Dated:
  
	
  
 
  	
  
 
  	
  
 
  
	
  
 
  	
  
 
  	
  
 
  
	
  
 
  	
  
LARGE SCALE BIOLOGY   CORPORATION
  
	
  
 
  	
  
 
  	
  
 
  
	
  
 
  	
  
By: 
  	
  
/s/  RONALD   J. ARTALE
  
	
   
  	
  
 
  	
  

  
	
  
 
  	
  
Name: 
  	
  
Ronald J. Artale
  
	
  
 
  	
  
Title:  
  	
  
Senior V.P., COO & CFO
  

NOTICE OF EXERCISE

To:          Large Scale Biology Corporation

                              (1)     The undersigned hereby elects to purchase ________ Warrant Shares of the Company pursuant to the terms of the attached Warrant, and tenders herewith payment of the exercise price in full, together with all applicable transfer taxes, if any.

                              (2)     Payment in lawful money of the United States shall take the form of (check applicable box):

                                                  
o wire transfer to the account of Large Scale Biology Corporation

                                                  
o  cashier’s check drawn on an United States bank payable to the order of Large Scale Biology Corporation

                              (3)     Please issue a certificate or certificates representing said Warrant Shares in the name of the undersigned or in such other name as is specified below:

	
  
 
  	
  

  	
  
 
  
	
  
 
  	
  
 
  	
  
 
  
	
  
The Warrant Shares shall be delivered to the   following:
  
	
  
 
  	
  
 
  	
  
 
  
	
   
  	
  
 
  	
  
 
  
	
  
 
  	
  

  	
  
 
  
	
  
 
  	
  
 
  	
  
 
  
	
  
 
  	
  
 
  	
  
 
  
	
  
 
  	
  

  	
  
 
  
	
  
 
  	
  
 
  	
  
 
  
	
  
 
  	
  
 
  	
  
 
  
	
  
 
  	
  

  	
  
 
  

                              (4)     Representations and Warranties.  The undersigned hereby affirms and makes as of this date the representations and warranties set forth in Section 18 of the Warrant.

	
  
 
  	
  
[PURCHASER]
  
	
  
 
  	
  
 
  	
  
 
  
	
  
 
  	
  
By:
  	
  
 
  
	
  
 
  	
  
 
  	
  

  
	
  
 
  	
  
Name:
  	
  
 
  
	
  
 
  	
  
Title:
  	
  
 
  
	
   
  	
  
 
  	
  
 
  
	
  
 
  	
  
Dated: 
  	
  
 
  
	
  
 
  	
  
 
  	
  

  

ASSIGNMENT FORM

(To assign the foregoing warrant, execute
 this form and supply required information. 
 Do not use this form to exercise the warrant.)

                              FOR VALUE RECEIVED, the foregoing Warrant and all rights evidenced thereby are hereby assigned to

_______________________________________________ whose address is

_______________________________________________________________.

_______________________________________________________________

	
   
  	
  
 
  	
  
                                        Dated:   ______________, _______
  
	
  
 
  	
  
Holder’s Signature:
  	
  
 
  	
  
 
  
	
  
 
  	
  
 
  	
  

  	
  
 
  
	
  
 
  	
  
Holder’s Address:
  	
  
 
  	
  
 
  
	
  
 
  	
  
 
  	
  

  	
  
 
  
	
  
 
  	
  
 
  	
  
 
  	
  
 
  
	
   
  	
  
 
  	
  
 
  	
  
 
  
	
  
 
  	
  
 
  	
  

  	
  
 
  
	
  
 
  	
  
 
  	
  
 
  
	
  
Signature Guaranteed:
  	
  
 
  	
  
 
  
	
  
 
  	
  

  	
  
 
  

NOTE:  The signature to this Assignment Form must correspond with the name as it appears on the face of the Warrant, without alteration or enlargement or any change whatsoever, and must be guaranteed by a bank or trust company.  Officers of corporations and those acting in a fiduciary or other representative capacity should file proper evidence of authority to assign the foregoing Warrant.  Transfer of this Warrant is restricted and subject to the provisions and restrictions set forth in the Warrant.Exhibit 4.2

REGISTRATION RIGHTS AGREEMENT

                              This Registration Rights Agreement (this “Agreement”) is made and entered into as of December 17, 2004, by and among Large Scale Biology Corporation, a Delaware corporation (the “Company”), and Kentucky Technology, Inc., a Kentucky corporation (“KTI” or “Purchaser”).

                              This Agreement is made pursuant to the Loan Agreement, dated as of the date hereof among the Company and the Purchaser (the “Loan Agreement”).

                              The Company and the Purchaser hereby agree as follows:

                 1.          Definitions.  Capitalized terms used and not otherwise defined herein that are defined in the Loan Agreement shall have the meanings given such terms in the Loan Agreement.  As used in this Agreement, the following terms shall have the following meanings:

                              “Advice” shall have the meaning set forth in Section 6(d).

	
   
  	
  
             “Effectiveness   Date” means, with respect to the Registration Statement required to be   filed hereunder, the earlier of (a) the 120th calendar day   following the Filing Date, and (b) the fifth Trading Day following the date   on which the Company is notified by the Commission that the Registration   Statement will not be reviewed or is no longer subject to further review and   comments.
  
	
  
 
  	
  
 
  
	
  
 
  	
  
                “Effectiveness Period” shall have the meaning set forth in Section 2.
  
	
  
 
  	
  
 
  
	
  
 
  	
  
                “Filing Date” means, with respect to the Registration Statement   required to be filed hereunder, the forty-fifth (45th) calendar   day following the earlier of i) the Revolving Credit Expiration Date as   defined in the Loan Agreement or ii) the Prepayment Date as defined in the   Loan Agreement.
  
	
  
 
  	
  
 
  
	
  
 
  	
  
                “Holder” or “Holders” means the holder or holders, as the case   may be, from time to time of Registrable Securities.
  
	
   
  	
  
 
  
	
  
 
  	
  
                “Indemnified Party” shall have the meaning set forth in Section 5(c).
  
	
  
 
  	
  
 
  
	
  
 
  	
  
                “Indemnifying Party” shall have the meaning set forth in Section 5(c).
  
	
  
 
  	
  
 
  
	
  
 
  	
  
                “Losses” shall have the meaning set forth in Section 5(a).
  
	
  
 
  	
  
 
  
	
  
 
  	
  
                “Proceeding” means an action, claim, suit, investigation or proceeding   (including, without limitation, an investigation or partial proceeding, such   as a deposition), whether commenced or threatened in writing.
  
	
   
  	
  
 
  
	
  
 
  	
  
                “Prospectus” means the prospectus included in the Registration   Statement (including, without limitation, a prospectus that includes any   information previously omitted from a prospectus filed as part of an   effective registration statement in reliance upon Rule 430A promulgated under   the Securities Act), as amended or supplemented by any prospectus supplement,   with respect to the terms of the offering of any portion of the Registrable   Securities covered by the Registration Statement, and all other amendments   and supplements to the Prospectus, including post-effective amendments, and   all material incorporated by reference or deemed to be incorporated by reference   in such Prospectus.
  
	
  
 
  	
  
 
  
	
  
 
  	
  
                “Registrable Securities” means all of the Warrant Shares, together   with any shares of Common Stock issued or issuable upon any stock split,   dividend or other distribution, recapitalization or similar event with respect   to the foregoing.
  
	
  
 
  	
  
 
  
	
  
 
  	
  
                “Registration Statement” means the registration statements required to   be filed hereunder, including (in each case) the Prospectus, amendments and   supplements to the registration statement or Prospectus, including pre- and   post-effective amendments, all exhibits thereto, and all material   incorporated by reference or deemed to be incorporated by reference in the   registration statement.
  

	
  
 
  	
  
                “Rule 415” means Rule 415 promulgated by the Commission pursuant to   the Securities Act, as such Rule may be amended from time to time, or any   similar rule or regulation hereafter adopted by the Commission having   substantially the same purpose and effect as such Rule.
  
	
  
 
  	
  
 
  
	
  
 
  	
  
                “Rule 424” means Rule 424 promulgated by the Commission pursuant to   the Securities Act, as such Rule may be amended from time to time, or any   similar rule or regulation hereafter adopted by the Commission having   substantially the same purpose and effect as such Rule.
  
	
  
 
  	
  
 
  
	
  
 
  	
  
                “Trading Day” means a day on which the Common Stock is traded on the   nasdaq Stock Market.
  

                 2.          Registration.  On or prior to the Filing Date, the Company shall prepare and file with the Commission the Registration Statement covering the resale of all of the Registrable Securities for an offering to be made on a continuous basis pursuant to Rule 415.  The Registration Statement required hereunder shall be on Form S-3 (except if the Company is not then eligible to register for resale the Registrable Securities on Form S-3, in which case the Registration shall be on another appropriate form in accordance herewith).  Subject to the terms of this Agreement, the Company shall use its reasonable efforts to cause the Registration Statement to be declared effective under the Securities Act as promptly as possible after the filing thereof, but in any event not later than the
Effectiveness Date, and shall use its reasonable efforts to keep the Registration Statement continuously effective under the Securities Act until the date when all Registrable Securities covered by the Registration Statement have been sold or may be sold without volume restrictions pursuant to Rule 144(k) as determined by the counsel to the Company pursuant to a written opinion letter to such effect, addressed and acceptable to the Company’s transfer agent and the affected Holders, and in no event later than the date two (2) years following the Effectiveness Date (the “Effectiveness Period”).

	
  
 
  	
  
3.          Registration   Procedures
  
	
  
 
  	
  
 
  
	
  
 
  	
  
             In   connection with the Company’s registration obligations hereunder, the Company   shall:
  
	
  
 
  	
  
 
  
	
  
 
  	
  
             (a)          Not   less than five Trading Days prior to the filing of the Registration Statement   or any related Prospectus or any amendment or supplement thereto, the Company   shall, (i) furnish to the Holders copies of all such documents proposed to be   filed (including documents incorporated or deemed incorporated by reference   to the extent requested by such Person) which documents will be subject to   the review of such Holders, and (ii) cause its officers and directors,   counsel and independent certified public accountants to respond to such   inquiries as shall be necessary, in the reasonable opinion of respective counsel   to conduct a reasonable investigation within the meaning of the Securities   Act.  The Company shall not file the   Registration Statement or any such Prospectus or any amendments or   supplements
thereto to which the Holders of a majority of the Registrable   Securities shall reasonably object in good faith, provided that the Company   is notified of such objection in writing no later than 5 Trading Days after   the Holders have been so furnished copies of such documents.
  
	
   
  	
  
 
  
	
  
 
  	
  
                (b)          (i) Prepare   and file with the Commission such amendments, including post-effective   amendments, to the Registration Statement and the Prospectus used in   connection therewith as may be necessary to keep the Registration Statement   continuously effective as to the applicable Registrable Securities for the   Effectiveness Period and prepare and file with the Commission such additional   Registration Statements in order to register for resale under the Securities   Act all of the Registrable Securities; (ii) cause the related Prospectus to   be amended or supplemented by any required Prospectus supplement, and as so   supplemented or amended to be filed pursuant to Rule 424; (iii) respond as   promptly as reasonably possible to any comments received from the Commission   with respect to the Registration Statement or any
amendment thereto and, as   promptly as reasonably possible, upon request, provide the Holders true and   complete copies of all correspondence from and to the Commission relating to   the Registration statement; and (iv) comply in all material respects with the   provisions of the Securities Act and the Exchange Act with respect to the   disposition of all Registrable Securities covered by the Registration   Statement during the applicable period in accordance with the intended methods   of disposition by the Holders thereof set forth in the Registration Statement   as so amended or in such Prospectus as so supplemented.
  

	
  
 
  	
  
             (c)          Notify   the Holders of Registrable Securities to be sold as promptly as reasonably   possible and (if requested by any such Person) confirm such notice in writing   promptly following the day (i)(A) when a Prospectus or any Prospectus   supplement or post-effective amendment to the Registration Statement is   proposed to be filed; (B) when the Commission notifies the Company whether   there will be a “review” of the Registration Statement and whenever the   Commission comments in writing on the Registration Statement (the Company   shall upon request provide true and complete copies thereof and all written   responses thereto to each of the Holders); and (C) with respect to the   Registration Statement or any post-effective amendment, when the same has   become effective; (ii) of any request by the Commission or
any other Federal   or state governmental authority during the period of effectiveness of the   Registration Statement for amendments or supplements to the Registration   Statement or Prospectus or for additional information; (iii) of the issuance   by the Commission or any other federal or state governmental authority of any   stop order suspending the effectiveness of the Registration Statement   covering any or all of the Registrable Securities or the initiation of any   Proceedings for that purpose; (iv) of the receipt by the Company of any   notification with respect to the suspension of the qualification or exemption   from qualification of any of the Registrable Securities for sale in any   jurisdiction, or the initiation or threatening of any Proceeding for such   purpose; and (v) of the occurrence of any event or passage of time that makes   the financial statements included in the Registration Statement ineligible   for inclusion therein or any statement made in the Registration Statement or
  Prospectus or any document incorporated or deemed to be incorporated therein   by reference untrue in any material respect or that requires any revisions to   the Registration Statement, Prospectus or other documents so that, in the   case of the Registration Statement or the Prospectus, as the case may be, it   will not contain any untrue statement of a material fact or omit to state any   material fact required to be stated therein or necessary to make the   statements therein, in light of the circumstances under which they were made,   not misleading.
  
	
   
  	
  
 
  
	
  
 
  	
  
             (d)          Use   commercially reasonable efforts to avoid the issuance of, or, if issued,   obtain the withdrawal of (i) any order suspending the effectiveness of the   Registration Statement, or (ii) any suspension of the qualification (or   exemption from qualification) of any of the Registrable Securities for sale   in any jurisdiction, at the earliest practicable moment.
  
	
  
 
  	
  
 
  
	
  
 
  	
  
             (e)             Furnish to each   Holder, without charge, at least one conformed copy of the Registration   Statement and each amendment thereto, including financial statements and   schedules, all documents incorporated or deemed to be incorporated therein by   reference to the extent requested by such Person, and all exhibits to the   extent requested by such Person (including those previously furnished or   incorporated by reference) promptly after the filing of such documents with   the Commission.
  
	
  
 
  	
  
 
  
	
  
 
  	
  
             (f)          Promptly   deliver to each Holder, without charge, as many copies of the Prospectus or   Prospectuses (including each form of prospectus) and each amendment or   supplement thereto as such Persons may reasonably request in connection with   resales by the Holder of Registrable Securities.  Subject to the terms of this Agreement, the Company hereby consents   to the use of such Prospectus and each amendment or supplement thereto by   each of the selling Holders in connection with the offering and sale of the   Registrable Securities covered by such Prospectus and any amendment or   supplement thereto, except after the giving of any notice pursuant to Section   3(c).
  
	
   
  	
  
 
  
	
  
 
  	
  
             (g)          Prior   to any resale of Registrable Securities by a Holder, use its commercially   reasonable efforts to register or qualify or cooperate with the selling   Holders in connection with the registration or qualification (or exemption   from the Registration or qualification) of such Registrable Securities for   the resale by the Holder under the securities or Blue Sky laws of such   jurisdictions within the United States as any Holder reasonably requests in   writing, to keep the Registration or qualification (or exemption therefrom)   effective during the Effectiveness Period and to do any and all other acts or   things reasonably necessary to enable the disposition in such jurisdictions   of the Registrable Securities covered by the Registration Statement; provided,   that the Company shall not be required to qualify
generally to do business in   any jurisdiction where it is not then so qualified, subject the Company to   any material tax in any such jurisdiction where it is not then so subject or   file a general consent to service of process in any such jurisdiction.
  
	
  
 
  	
  
 
  
	
  
 
  	
  
             (h)          If   requested by the Holders, cooperate with the Holders to facilitate the timely   preparation and delivery of certificates representing Registrable Securities   to be delivered to a transferee pursuant to the Registration Statement, which   certificates shall be free, to the extent permitted by the Loan Agreement, of   all restrictive legends, and to enable such Registrable Securities to be in   such denominations and registered in such names as any such Holders may   reasonably request.
  

	
  
 
  	
  
                  (i)          Upon
     the occurrence of any event contemplated by Section 3(c)(v), as promptly as
     reasonably possible, prepare a supplement or amendment, including a
     post-effective amendment, to the Registration Statement or a supplement to
     the related Prospectus or any document incorporated or deemed to be
     incorporated therein by reference, and file any other required document so
     that, as thereafter delivered, neither the Registration Statement nor such
     Prospectus will contain an untrue statement of a material fact or omit to
     state a material fact required to be stated therein or necessary to make
     the statements therein, in light of the circumstances under which they were
     made, not misleading.   If the Company notifies the Holders in
     accordance with clauses (ii) through (v) of Section 3(c) above to suspend
     the use of any Prospectus until the requisite changes to such Prospectus
     have been made, then the Holders shall suspend use of such
     Prospectus.  The Company will use its best efforts to ensure that the
     use of the Prospectus may be resumed as promptly as is practicable. 
     The Company shall be entitled to exercise its right under this Section 3(i)
     to suspend the availability of a Registration Statement and Prospectus, for
     a period not to exceed 60 days (which need not be consecutive days) in any
     12-month period.  Such period will be extended to 90 days in the event
     that (1) the Company would, in accordance with the advice of its counsel,
     be required to disclose in the Prospectus information not otherwise then
     required by law to be publicly disclosed, and (2) in the good faith
     judgment of the Company’s Board of Directors, there is a reasonable
     likelihood that such disclosure, or any other action to be taken in
     connection with the prospectus, would materially and adversely affect or
     interfere with any financing, transaction with a strategic partner (not in
     the ordinary course of business), acquisition, merger, disposition of
     assets (not in the ordinary course of business), corporate reorganization
     or other similar transaction involving the Company

  
	
   
 
   	
   
 
   
	
    
   	
   
             (j)          Comply    with all applicable rules and regulations of the Commission.
   
	
   
 
   	
   
 
   
	
   
 
   	
   
             (k)          The    Company may require each selling Holder to furnish to the Company a    certified statement as to the number of shares of Common Stock beneficially    owned by such Holder and, if required by the Commission, the person thereof    that has voting and dispositive control over the Shares. During any periods    that the Company is unable to meet its obligations hereunder with respect to    the registration of the Registrable Securities solely because any Holder    fails to furnish such information within three Trading Days of the Company’s    request, any liquidated damages that are accruing at such time as to such    Holder only shall be tolled and any Event that may otherwise occur solely    because of such delay shall be suspended as to such Holder only, until such    information is delivered to the
Company.
   

                                4.          
Registration Expenses.  All fees and expenses incident to the performance of or
     compliance with this Agreement by the Company shall be borne by the Company
     whether or not any Registrable Securities are sold pursuant to the
     Registration Statement.  The fees and expenses referred to in the
     foregoing sentence shall include, without limitation, (i) all registration
     and filing fees (including, without limitation, fees and expenses (A) with
     respect to filings required to be made with the nasdaq Stock Market, and
     (B) in compliance with applicable state securities or Blue Sky laws), (ii)
     printing expenses (including, without limitation, expenses of printing
     certificates for Registrable Securities and of printing prospectuses if the
     printing of prospectuses is reasonably requested by the holders of a
     majority of the Registrable Securities included in the Registration
     Statement), (iii) messenger, telephone and delivery expenses, (iv) fees and
     disbursements of counsel for the Company, (v) Securities Act liability
     insurance, if the Company so desires such insurance, and (vi) fees and
     expenses of all other Persons retained by the Company in connection with
     the consummation of the transactions contemplated by this Agreement. 
     In addition, the Company shall be responsible for all of its internal
     expenses incurred in connection with the consummation of the transactions
     contemplated by this Agreement (including, without limitation, all salaries
     and expenses of its officers and employees performing legal or accounting
     duties), the expense of any annual audit and the fees and expenses incurred
     in connection with the listing of the Registrable Securities on any
     securities exchange as required hereunder. In no event shall the Company be
     responsible for any broker or similar commissions or, except to the extent
     provided for in the Transaction Documents, any legal fees or other costs of
     the Holders.

 	
   
 
   	
   
5.               Indemnification
   
	
   
 
   	
   
 
   
	
   
 
   	
   
             (a)          Indemnification    by the Company.  The Company    shall, notwithstanding any termination of this Agreement, indemnify and hold    harmless each Holder, the officers, directors, agents and employees of each    of them, each Person who controls any such Holder (within the meaning of    Section 15 of the Securities Act or Section 20 of the Exchange Act) and the    officers, directors, agents and employees of each such controlling Person,    to the fullest extent permitted by applicable law, from and against any and    all losses, claims, damages, liabilities, costs (including, without    limitation, reasonable attorneys’ fees) and expenses (collectively, “Losses”),    as incurred, arising out of or relating to any untrue or alleged untrue    statement of a material fact contained in the
Registration Statement, any    Prospectus or any form of prospectus or in any amendment or supplement    thereto or in any preliminary prospectus, or arising out of or relating to    any omission or alleged omission of a material fact required to be stated therein    or necessary to make the statements therein (in the case of any Prospectus    or form of prospectus or supplement thereto, in light of the circumstances    under which they were made) not misleading, except to the extent, but only    to the extent, that (i) such untrue statements or omissions are based upon    information regarding such Holder furnished in writing to the Company by    such Holder expressly for use therein, or to the extent that such    information relates to such Holder or such Holder’s proposed method of    distribution of Registrable Securities and was reviewed and expressly    approved in writing by such Holder expressly for use in the Registration    Statement, such Prospectus or such form of Prospectus or in any
amendment or    supplement thereto or (ii) in the case of an occurrence of an event of the    type specified in Section 3(c)(ii)-(v), the use by such Holder of an    outdated or defective Prospectus after the Company has notified such Holder    in writing that the Prospectus is outdated or defective and prior to the    receipt by such Holder of the Advice contemplated in Section 6(d).  The Company shall notify the Holders    promptly of the institution, threat or assertion of any Proceeding of which    the Company is aware in connection with the transactions contemplated by    this Agreement.
   
	
    
   	
   
 
   
	
   
 
   	
   
             (b)          Indemnification    by Holders. Each Holder shall, severally and not jointly, indemnify and    hold harmless the Company, its directors, officers, agents and employees,    each Person who controls the Company (within the meaning of Section 15 of    the Securities Act and Section 20 of the Exchange Act), and the directors,    officers, agents or employees of such controlling Persons, to the fullest    extent permitted by applicable law, from and against all Losses, as incurred,    to the extent arising out of or based solely upon: (x) such Holder’s failure    to comply with the prospectus delivery requirements of the Securities Act or    (y) any untrue or alleged untrue statement of a material fact contained in    any Registration Statement, any Prospectus, or any form of prospectus, or in    any amendment or
supplement thereto or in any preliminary prospectus, or    arising out of or relating to any omission or alleged omission of a material    fact required to be stated therein or necessary to make the statements    therein not misleading (i) to the extent, but only to the extent, that such    untrue statement or omission is contained in any information so furnished in    writing by such Holder to the Company specifically for inclusion in the    Registration Statement or such Prospectus or (ii) to the extent that (1)    such untrue statements or omissions are based solely upon information    regarding such Holder furnished in writing to the Company by such Holder    expressly for use therein, or to the extent that such information relates to    such Holder or such Holder’s proposed method of distribution of Registrable    Securities and was reviewed and expressly approved in writing by such Holder    expressly for use in the Registration Statement, such Prospectus or such    form of Prospectus or in
any amendment or supplement thereto or (2) in the    case of an occurrence of an event of the type specified in Section    3(c)(ii)-(v), the use by such Holder of an outdated or defective Prospectus    after the Company has notified such Holder in writing that the Prospectus is    outdated or defective and prior to the receipt by such Holder of the Advice    contemplated in Section 6(d).  In no    event shall the liability of any selling Holder hereunder be greater in    amount than the dollar amount of the net proceeds received by such Holder    upon the sale of the Registrable Securities giving rise to such    indemnification obligation.
   
	
    
   	
   
 
   
	
   
 
   	
   
             (c)          Conduct    of Indemnification Proceedings. If any Proceeding shall be brought or    asserted against any Person entitled to indemnity hereunder (an “Indemnified    Party”), such Indemnified Party shall promptly notify the Person from    whom indemnity is sought (the “Indemnifying Party”) in writing, and    the Indemnifying Party shall have the right to assume the defense thereof,    including the employment of counsel reasonably satisfactory to the    Indemnified Party and the payment of all fees and expenses incurred in    connection with defense thereof; provided, that the failure of any    Indemnified Party to give such notice shall not relieve the Indemnifying    Party of its obligations or liabilities pursuant to this Agreement, except    (and only) to the extent that it shall be
finally determined by a court of    competent jurisdiction (which determination is not subject to appeal or    further review) that such failure shall have prejudiced the Indemnifying    Party.
   

	
   
 
   	
   
             An    Indemnified Party shall have the right to employ separate counsel in any    such Proceeding and to participate in the defense thereof, but the fees and    expenses of such counsel shall be at the expense of such Indemnified Party    or Parties unless:  (1) the    Indemnifying Party has agreed in writing to pay such fees and expenses; (2)    the Indemnifying Party shall have failed promptly to assume the defense of    such Proceeding and to employ counsel reasonably satisfactory to such    Indemnified Party in any such Proceeding; or (3) the named parties to any    such Proceeding (including any impleaded parties) include both such    Indemnified Party and the Indemnifying Party, and such Indemnified Party    shall reasonably believe that a material conflict of interest is likely to    exist if the same counsel were to represent such Indemnified Party and the    Indemnifying
Party (in which case, if such Indemnified Party notifies the    Indemnifying Party in writing that it elects to employ separate counsel at    the expense of the Indemnifying Party, the Indemnifying Party shall not have    the right to assume the defense thereof and the reasonable fees and expenses    of one separate counsel shall be at the expense of the Indemnifying    Party).  The Indemnifying Party shall    not be liable for any settlement of any such Proceeding effected without its    written consent, which consent shall not be unreasonably withheld.  No Indemnifying Party shall, without the    prior written consent of the Indemnified Party, effect any settlement of any    pending Proceeding in respect of which any Indemnified Party is a party,    unless such settlement includes an unconditional release of such Indemnified    Party from all liability on claims that are the subject matter of such    Proceeding.
   
	
    
   	
   
 
   
	
   
 
   	
   
             Subject    to the terms of this Agreement, all reasonable fees and expenses of the    Indemnified Party (including reasonable fees and expenses to the extent    incurred in connection with investigating or preparing to defend such    Proceeding in a manner not inconsistent with this Section) shall be paid to    the Indemnified Party, as incurred, within ten Trading Days of written    notice thereof to the Indemnifying Party; provided, that the Indemnified    Party shall promptly reimburse the Indemnifying Party for that portion of    such fees and expenses applicable to such actions for which such Indemnified    Party is not entitled to indemnification hereunder, determined based upon    the relative faults of the parties.
   
	
   
 
   	
   
 
   
	
   
 
   	
   
             (d)          Contribution.  If a claim for indemnification under    Section 5(a) or 5(b) is unavailable to an Indemnified Party (by reason of    public policy or otherwise), then each Indemnifying Party, in lieu of indemnifying    such Indemnified Party, shall contribute to the amount paid or payable by    such Indemnified Party as a result of such Losses, in such proportion as is    appropriate to reflect the relative fault of the Indemnifying Party and    Indemnified Party in connection with the actions, statements or omissions    that resulted in such Losses as well as any other relevant equitable    considerations.  The relative fault    of such Indemnifying Party and Indemnified Party shall be determined by    reference to, among other things, whether any action in question, including    any untrue or alleged untrue
statement of a material fact or omission or    alleged omission of a material fact, has been taken or made by, or relates    to information supplied by, such Indemnifying Party or Indemnified Party,    and the parties’ relative intent, knowledge, access to information and    opportunity to correct or prevent such action, statement or omission.  The amount paid or payable by a party as    a result of any Losses shall be deemed to include, subject to the    limitations set forth in this Agreement, any reasonable attorneys’ or other    reasonable fees or expenses incurred by such party in connection with any    Proceeding to the extent such party would have been indemnified for such    fees or expenses if the indemnification provided for in this Section was    available to such party in accordance with its terms.
   
	
    
   	
   
 
   
	
   
 
   	
   
             The    parties hereto agree that it would not be just and equitable if contribution    pursuant to this Section 5(d) were determined by pro rata allocation or by    any other method of allocation that does not take into account the equitable    considerations referred to in the immediately preceding paragraph.  Notwithstanding the provisions of this    Section 5(d), no Holder shall be required to contribute, in the aggregate,    any amount in excess of the amount by which the proceeds actually received    by such Holder from the sale of the Registrable Securities subject to the    Proceeding exceeds the amount of any damages that such Holder has otherwise    been required to pay by reason of such untrue or alleged untrue statement or    omission or alleged omission, except in the case of fraud by such Holder.
   
	
   
 
   	
   
 
   
	
   
 
   	
   
             The    indemnity and contribution agreements contained in this Section are in    addition to any liability that the Indemnifying Parties may have to the    Indemnified Parties.
   
	
   
 
   	
   
 
   
	
   
 
   	
   
6.           Miscellaneous
   
	
    
   	
   
 
   
	
   
 
   	
   
             (a)          Remedies.  In the event of a breach by the Company    or by a Holder, of any of their obligations under this Agreement, each Holder    or the Company, as the case may be, in addition to being entitled to    exercise all rights granted by law and under this Agreement, including    recovery of damages, will be entitled to specific performance of its rights    under this Agreement.  The Company and    each Holder agree that monetary damages would not provide adequate    compensation for any losses incurred by reason of a breach by it of any of    the provisions of this Agreement and hereby further agrees that, in the    event of any action for specific performance in respect of such breach, it    shall waive the defense that a remedy at law would be adequate.
   

	
   
 
   	
   
             (b)          No    Piggyback on Registrations.     Neither the Company nor any of its security holders (other than the    Holders in such capacity pursuant hereto) may include securities of the    Company in a Registration Statement other than the Registrable    Securities.  No Person has any right    to cause the Company to effect the registration under the Securities Act of    any securities of the Company.  The    Company shall not file any other registration statement (on than on Form    S-8) until after the Effective Date.
   
	
    
   	
   
 
   
	
   
 
   	
   
             (c)          Compliance.  Each Holder covenants and agrees that it    will comply with the prospectus delivery requirements of the Securities Act    as applicable to it in connection with sales of Registrable Securities    pursuant to the Registration Statement.
   
	
   
 
   	
   
 
   
	
   
 
   	
   
             (d)          Discontinued    Disposition.  Each Holder agrees    by its acquisition of such Registrable Securities that, upon receipt of a    notice from the Company of the occurrence of any event of the kind described    in Section 3(c), such Holder will forthwith discontinue disposition of such    Registrable Securities under the Registration Statement until such Holder’s    receipt of the copies of the supplemented Prospectus and/or amended    Registration Statement or until it is advised in writing (the “Advice”)    by the Company that the use of the applicable Prospectus may be resumed,    and, in either case, has received copies of any additional or supplemental    filings that are incorporated or deemed to be incorporated by reference in    such Prospectus or Registration Statement.     The
Company will use its reasonable efforts to ensure that the use of    the Prospectus may be resumed as promptly as it practicable.
   
	
   
 
   	
   
 
   
	
    
   	
   
             (e)          Piggy-Back    Registrations.  If at any time    during the Effectiveness Period there is not an effective Registration    Statement covering all of the Registrable Securities and the Company shall    determine to prepare and file with the Commission a registration statement    relating to an offering for its own account or the account of others under    the Securities Act of any of its equity securities, other than on Form S-4    or Form S-8 (each as promulgated under the Securities Act) or their then    equivalents relating to equity securities to be issued solely in connection    with any acquisition of any entity or business or equity securities issuable    in connection with the stock option or other employee benefit plans, then    the Company shall send to each Holder a written notice of such determination
and, if within fifteen days after the date of such notice, any such Holder    shall so request in writing, the Company shall include in such registration    statement all or any part of such Registrable Securities such Holder    requests to be registered, subject to customary underwriter cutbacks    applicable to all holders of registration rights and the other terms and    conditions of such offering, including without limitation the execution by    the participating Holders of an underwriting agreement in the form to be    used in connection with such offering.
   
	
   
 
   	
   
 
   
	
   
 
   	
   
             (f)          Amendments    and Waivers.  The provisions of    this Agreement, including the provisions of this sentence, may not be    amended, modified or supplemented, and waivers or consents to departures    from the provisions hereof may not be given, unless the same shall be in    writing and signed by the Company and Holders of 66% of the then outstanding    Registrable Securities, and in such case the same shall be binding upon all    Holders.
   
	
    
   	
   
 
   
	
   
 
   	
   
             (g)          Notices.  Any and all notices or other    communications or deliveries required or permitted to be provided hereunder    shall be made in accordance with the provisions of the Loan Agreement.
   
	
   
 
   	
   
 
   
	
   
 
   	
   
             (h)          Successors    and Assigns.  This Agreement    shall inure to the benefit of and be binding upon the successors and    permitted assigns of each of the parties and shall inure to the benefit of    each Holder.  Each Holder may assign    its respective rights hereunder to the acquirer from such Holder of at least    25,000 shares of Registrable Securities in the manner and to the Persons as    permitted under the Loan Agreement.
   
	
   
 
   	
   
 
   
	
   
 
   	
   
             (i)          Execution    and Counterparts.  This Agreement    may be executed in any number of counterparts, each of which when so    executed shall be deemed to be an original and, all of which taken together    shall constitute one and the same Agreement.  In the event that any signature is delivered by facsimile    transmission, such signature shall create a valid binding obligation of the    party executing (or on whose behalf such signature is executed) the same    with the same force and effect as if such facsimile signature were the    original thereof.
   
	
    
   	
   
 
   
	
   
 
   	
   
             (j)          Governing    Law.  All questions concerning    the construction, validity, enforcement and interpretation of this Agreement    shall be determined in accordance with the provisions of the Loan Agreement.
   
	
   
 
   	
   
 
   
	
   
 
   	
   
             (k)          Cumulative    Remedies.  The remedies provided    herein are cumulative and not exclusive of any remedies provided by law.
   

	
   
 
   	
   
             (l)          Severability.    If any term, provision, covenant or restriction of this Agreement is held by    a court of competent jurisdiction to be invalid, illegal, void or    unenforceable, the remainder of the terms, provisions, covenants and    restrictions set forth herein shall remain in full force and effect and    shall in no way be affected, impaired or invalidated, and the parties hereto    shall use their commercially reasonable efforts to find and employ an    alternative means to achieve the same or substantially the same result as    that contemplated by such term, provision, covenant or restriction.  It is hereby stipulated and declared to    be the intention of the parties that they would have executed the remaining    terms, provisions, covenants and restrictions without including any of such    that may be
hereafter declared invalid, illegal, void or unenforceable.
   
	
    
   	
   
 
   
	
   
 
   	
   
             (m)          Headings.  The headings in this Agreement are for    convenience of reference only and shall not limit or otherwise affect the    meaning hereof.
   
	
   
 
   	
   
 
   
	
   
 
   	
   
             (n)          Independent    Nature of Purchasers’ Obligations and Rights.  The obligations of each Holder hereunder are several and not    joint with the obligations of any other Holder hereunder, and no Holder    shall be responsible in any way for the performance of the obligations of    any other Holder hereunder.  Nothing    contained herein or in any other agreement or document delivered at any    closing, and no action taken by any Holder pursuant hereto or thereto, shall    be deemed to constitute the Holders as a partnership, an association, a    joint venture or any other kind of entity, or create a presumption that the    Holders are in any way acting in concert with respect to such obligations or    the transactions contemplated by this Agreement.  Each Holder shall be entitled to protect and enforce
its    rights, including without limitation the rights arising out of this    Agreement, and it shall not be necessary for any other Holder to be joined    as an additional party in any proceeding for such purpose.
   

 
[The  balance of this page intentionally left blank]

                                        IN  WITNESS WHEREOF, the parties have executed this Registration Rights Agreement  as of the date first written above.
 	
   
 
   	
   
LARGE SCALE BIOLOGY CORPORATION
   
	
   
 
   	
   
 
   	
   
 
   
	
   
 
   	
   
By:
   	
   
/s/  RONALD J. ARTALE
   
	
   
 
   	
   
 
   	
   

   
	
    
   	
   
Name: 
   	
   
Ronald J. Artale
   
	
   
 
   	
   
Title: 
   	
   
Senior Vice President, COO, CFO
   
	
   
 
   	
   
 
   	
   
 
   

	
   
 
   	
   
KENTUCKY TECHNOLOGY, INC.
   
	
   
 
   	
   
 
   	
   
 
   
	
   
 
   	
   
By:  
   	
       /s/  JOHN B.
        PARKS

    
	
    
   	
    
   	
   

   
	
    
   	
   Name: 
   	
   John B. Parks
   
	
    
   	
   Title: 
   	
   President

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00076-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00076-of-00352.parquet"}]]