Document:

EMPLOYMENT AGREEMENT

THIS EMPLOYMENT AGREEMENT (this "Agreement") between Vadim Babenko,  residing at
7501 Heatherton Lane, Potomac,  MD 20854,  ("Employee"),  and INFORMAX,  INC., a
Delaware corporation with offices at 6010 Executive Boulevard, 10th floor, North
Bethesda,  Maryland 20852  ("InforMax" or the "Company") is made effective as of
July 14, 2000 (the "Effective  Date") and sets forth the terms and conditions of
Employee's continued employment by InforMax.

                                   WITNESSETH

     WHEREAS, Employee is presently employed by InforMax; and

     WHEREAS,  InforMax  believes that it is in the best interest of InforMax to
assure the continued  services of Employee on behalf of InforMax under the terms
and conditions set forth herein; and

     NOW THEREFORE, in consideration of the premises and of the mutual covenants
and conditions contained in this Agreement,  the parties hereto, intending to be
legally bound, agree as follows:

     1.  EMPLOYMENT.  . Informax  hereby  employs  Employee and Employee  hereby
accepts  continued  employment  with Informax upon the terms and  conditions set
forth in this Agreement.  Employee's principal titles and responsibilities shall
be that of Chief Technology Officer. Employee's sole duties and responsibilities
in the Company shall be to participate in the day-to-day  operations of software
development for the Company and to supervise software developers and programmers
of the  Company.  It is  expressly  understood  that  Employee  shall  not  have
policy-making  functions  or authority in the Company in carrying out his duties
and shall not  participate  in management of the Company other than as expressly
set forth in this  paragraph.  Employee  shall  report to and be directed by the
Chief Executive Officer ("CEO") with respect to his duties and responsibilities.
Both  Employee  and  Informax  reserve  the  right  to  change   Employee's  job
responsibilities  and  title  on a  mutually  agreeable  basis  should  that  be
desirable in the future.

     2. TERM OF  AGREEMENT.  The term of this  Agreement  shall  commence on the
Effective Date, and, except as otherwise  provided  herein,  shall terminate two
(2) years  thereafter.  The Agreement shall  automatically  renew for additional
terms of one (1) year  unless,  not less than  ninety  (90) days before the next
termination  date of the Agreement,  either party provides  notice in writing to
the other that it does not intend to renew the Agreement.

<PAGE>

     3. COMPENSATION.

     (a) Base Salary.  InforMax shall pay, and Employee shall accept, during the
term of this  Agreement,  as  compensation  for services  rendered  hereunder an
annual salary of $285,000 payable in semi-monthly  payments,  with increases and
bonuses annually at the discretion of the CEO.

     (b)  Benefit  Plans.  Employee  shall be entitled  to  participate  in such
benefit  plan(s) of InforMax now in existence or which may hereafter  during the
term of this  Agreement  become  effective  for Senior  Executives  of InforMax.
Nothing in this Section 3(c) shall be deemed to prevent  InforMax  from altering
or  abolishing  any of such  plans or  benefits  provided  that all such  Senior
Executives are treated equally.

     (c) Vacation. During the term of this Agreement, Employee shall be entitled
to a minimum of three (3) weeks paid vacation in accordance with the established
policy of InforMax,  or such other greater number of days pursuant to an amended
policy in effect at the relevant  time.  Employee  also shall be entitled to all
paid holidays and personal days given by InforMax.

     (d)  Expenses.  InforMax  shall  promptly  pay or reimburse  Employee  upon
submission of vouchers or receipts, and such other documentation as InforMax may
request, for all reasonable  out-of-pocket  expenses for entertainment,  travel,
meals, hotel  accommodations  and the like,  incurred by him that are reasonably
related to the performance of his duties.

     (e)  Withholding.  Employee  acknowledges  that  InforMax may withhold from
amounts payable to Employee under this Agreement with respect to certain income,
unemployment and social security taxes required to be withheld from the wages of
employees under applicable Federal,  State, and local law. No other taxes, fees,
impositions,  duties or other  charges of any kind shall be deducted or withheld
from amounts payable hereunder, unless otherwise required by law or agreed to by
Employee.

     4. TERMINATION OF EMPLOYMENT.  Notwithstanding any provisions herein to the
contrary,  Employee's  employment  with InforMax may be terminated  prior to the
completion of the term described in Section 2 of this Agreement,  subject to the
following terms and conditions:

     (a) Termination for Cause.  InforMax may terminate Employee's employment at
any time for Cause.  For the purpose of this  Agreement,  the term "Cause" shall
mean Employee's: (1) willful misconduct; (2) gross negligence or incompetence in
the  performance  of his  duties;  (3)  willful  violation  of any law,  rule or
regulation  (other  than  traffic  violations  or  similar  offenses)  or  final
cease-and-desist  order in performance of his duties;  or (4) material

                                       2
<PAGE>

breach of any provision of this Agreement  which breach  continues for more than
five (5) days after receiving written notice from InforMax.

     (b) Termination Without Cause upon a Change of Control.  InforMax shall pay
Employee  a sum equal to his  annual  base  salary  at the time of a "Change  in
Control" upon  termination  by InforMax of Employee's  employment  without Cause
within 180 days of a "Change in  Control".  For the  purposes of this  Section a
"Change of Control" of the Company  shall be deemed to have  occurred if (i) any
persons or  entities  other than a person  currently a  beneficial  owner of the
Company's  securities  becomes,  after the date hereof,  the beneficial owner of
securities of the Company  representing 50% of more of the combined voting power
of the Company's then outstanding  securities,  or (ii) the Company sells all or
substantially all or substantially all of its assets.

     (c) Termination Without Cause other than upon a Change of Control. InforMax
shall pay  Employee a  lump-sum  cash  payment in an amount  equal to his annual
salary upon termination by InforMax of Employee's employment without Cause other
than as provided in Section 4(b) above.  The severance  payment shall be paid to
Employee in cash as promptly as  practicable,  but in no event later than thirty
(30) days following the termination of his employment.

     (d) Voluntary  Termination by Employee  without Cause.  Any  termination of
Employee's employment by resignation, retirement or any other action of Employee
shall be deemed to be a "Voluntary  Termination."  Employee  shall give InforMax
thirty (30) days notice prior to the effective time of a Voluntary Termination.

     (e) Payment Upon Termination For Cause or Voluntary Termination. InforMax's
obligation to pay Employee any and all  compensation and benefits shall cease in
the event of a Termination  for Cause or a Voluntary  Termination,  and InforMax
shall not be liable for any further  payments to Employee  hereunder  except for
accrued salary,  accrued  vacation days,  reimbursement  of appropriate  expense
vouchers,  applicable indemnification obligations and other benefit continuation
obligations imposed by law.

     5. DEVOTION OF TIME.  Except for vacations as provided  herein and absences
due to temporary  illness or family  emergencies,  Employee agrees to devote his
full business time, best efforts and undivided attention and energies during the
term  of  this  Agreement  to the  performance  of  his  duties  and to  advance
InforMax's  interests.  During the term of this  Agreement,  Employee shall not,
without the prior written  approval of the Board of Directors,  or its designee,
be engaged in any other business  activity which, in the reasonable  judgment of
the Board of Directors,  conflicts  with the duties of Employee,  whether or not
such  business  activity  is  pursued  for  gain,  profit,  or  other  pecuniary
advantage;  but this restriction  shall not be construed as preventing  Employee
from investing his assets in such form or manner as will not

                                       3
<PAGE>

require the performance of services of Employee in the operations of the affairs
of  the   enterprises  or  companies  in  which  said   investments   are  made.
Notwithstanding  the  foregoing,  services,  which are neither  substantial  nor
significant,  individually or in the aggregate,  shall be permitted with respect
to investments  of Employee  provided that they shall not have an adverse effect
on Employee's duties hereunder.

     6. NON-COMPETITION; NON-SOLICITATION; NON-HIRE. Employee agrees that during
the term of this  Agreement and for a period of two years after  termination  of
this Agreement:

          a) Employee  shall not,  directly,  indirectly  or in concert with any
     other  person or entity  (whether  for or on behalf of  Employee or for any
     entity in which Employee  shall have a direct or indirect  interest (or any
     subsidiary  or  affiliate  of any such  entity),  whether as a  proprietor,
     partner,  co-venturer,   financier,  investor  or  stockholder,   director,
     officer, employer, employee, consultant,  servant, agent, representative or
     otherwise), solicit, attempt to solicit, service or attempt to service, any
     entity  or  individual  who  (a) is a  customer  of  InforMax  at the  time
     Employee's employment is terminated,  (b) was a customer of InforMax during
     the one  (1)-year  period  preceding  the  date  Employee's  employment  is
     terminated or (c) is, at the time  Employee's  employment is terminated,  a
     prospective customer of InforMax.

          b) Employee will not, directly or indirectly,  on Employee's behalf or
     in the  service or on behalf of  others,  render or be  retained  to render
     services whether as an officer, partner, trustee,  consultant, or employee,
     for any business  engaged in the Same Business as InforMax  including,  but
     not limited to, any  customer of InforMax  for whom  Employee  has provided
     services  during  Employee's  employment  with  InforMax.  As  used in this
     Agreement, the term "Same Business" means any business in which InforMax is
     engaged at the time of  termination  or any  business in which the Board of
     Directors has given the management of InforMax the approval to engage in as
     of the date of termination.

          c)  Employee  shall not,  directly  or  indirectly,  hire or engage or
     attempt to hire or engage any  individual  who shall have been a consultant
     or employee of InforMax as of the date Employee's  employment is terminated
     or at any time during the one (1)- year period prior to such date,  whether
     for or on behalf of Employee or for any entity in which Employee shall have
     a direct or indirect  interest (or any  subsidiary or affiliate of any such
     entity), whether as a proprietor, partner, co-venturer, financier, investor
     or stockholder, director, officer, employer, employee, consultant, servant,
     agent, representative or otherwise.

          d) The  business  of  InforMax  is  international  in  scope  and  the
     restrictions of this paragraph shall accordingly apply worldwide.

                                       4
<PAGE>

     7. NONDISCLOSURE OF PROPRIETARY INFORMATION. Both during and after the term
of this Agreement,  Employee agrees to preserve and protect the  confidentiality
of Proprietary Information as defined in Section 8 below. In addition,  Employee
will not (i) disclose or disseminate Proprietary Information to any third party,
including  employees of InforMax without a need to know, or (ii) use Proprietary
Information  for his own  benefit  or for the  benefit  of any third  party.  If
Employee receives information with uncertain confidentiality, he agrees to treat
the information as Proprietary  Information until management has verified to him
that such information is neither  confidential nor proprietary.  Notwithstanding
the foregoing  limitations,  Employee shall not be required to keep confidential
pursuant to this Section 7 any  Proprietary  Information  that:  (i) is known or
available through other lawful sources,  or (ii) is or becomes publicly known or
generally known in the industry  through no fault of Employee or his agents,  or
(iii) is  required  to be  disclosed  pursuant  to any  statutes,  laws,  rules,
regulations,   ordinances,  codes,  directives,  writs,  injunctions,   decrees,
judgments,  and orders of any  governmental  body (provided the Company is given
reasonable prior notice).

     8.  DEFINITION  OF  PROPRIETARY  INFORMATION.  Proprietary  Information  is
defined  as  information  regarding  InforMax's  current  and  planned  business
activities,  including (i)  information  which  relates to InforMax's  actual or
anticipated  products,  software,  research inventions,  processes,  techniques,
designs or other  technical  data; (ii)  information  regarding  administrative,
financial or marketing  activities of InforMax;  (iii) information received from
InforMax  clients and other third  parties;  and (iv) any materials or documents
containing  any of the  above  information.  Proprietary  Information  does  not
include  information which is or becomes publicly  available without a breach of
this Agreement by Employee.

     9. RETURN OF PROPRIETARY  INFORMATION.  Upon  termination of his employment
with  InforMax,   Employee   agrees  to  deliver  to  InforMax  all  Proprietary
Information  and any and all documents and other tangibles  including  diskettes
and  other   electronic  or  other  storage  media  containing  any  Proprietary
Information in whole or part.

     10. TRADE  SECRETS.  Employee  understands  and agrees that the  covenants,
restrictions and prohibitions against disclosure of Proprietary  Information set
forth in this  Agreement  are in addition  to, and not in lieu of, any rights or
remedies  which  InforMax  may  have  available  pursuant  to  the  laws  of any
jurisdiction  or at  common  law to  prevent  disclosure  of  trade  secrets  or
proprietary  information,  and the  enforcement  by  InforMax  of its rights and
remedies  pursuant to this  Agreement  shall not be construed as a waiver of any
other rights or available  remedies which it may possess in law or equity absent
this Agreement.

     11.  OWNERSHIP OF WORKS.  During the time Employee is employed by InforMax,
InforMax shall own all rights, including, without limitation, all trade secrets,
patents  and  copyrights,  in and to the  following  works  created by  Employee
whether created on InforMax's

                                       5

<PAGE>

premises or at some other  location:  (i) works  which  relate to or are derived
from the actual or anticipated  business of InforMax and (ii) works which result
from or are derived  from any task  assigned to  Employee or work  performed  by
Employee for InforMax (collectively, the "Works"). InforMax shall own such Works
even  if  created  outside  normal  working  hours  and  regardless  of  whether
Employee's  own equipment or InforMax's  equipment was used to create the Works.
Such Works shall include program codes and documentation. To the extent that any
such Works do not  qualify as works  made for hire  under  U.S.  copyright  law,
pursuant to this Agreement  Employee hereby grants an irrevocable  assignment to
InforMax of the ownership of, and all right, title and interest of copyright in,
such Works.  Employee  agrees to give InforMax or its  designees all  assistance
reasonably  required to perfect such rights provided that following  termination
of this Agreement, InforMax shall reimburse Employee for his reasonable time and
expense in assisting with such matters.

     12. INVENTIONS.  If Employee  individually or jointly makes or conceives of
any invention, technique, process, or other know-how, whether patentable or not,
in the course of performing  services for InforMax,  which relates in any manner
to the actual or  anticipated  business  of  InforMax  or results  from any task
assigned to Employee or work  performed by Employee for InforMax  (collectively,
"Inventions"),  Employee  will and hereby  does  assign to  InforMax  his entire
right,  title and interest in such  Inventions.  Employee will disclose any such
Inventions  to an officer of InforMax and will,  upon  request,  promptly sign a
specific  assignment  of title to  InforMax,  and do  anything  else  reasonably
necessary  to enable  InforMax  to  secure  patents,  trade  secret or any other
proprietary  rights in the United  States or foreign  countries,  provided  that
following  termination of this Agreement,  InforMax shall reimburse Employee for
his reasonable  time and expense in assisting with such matters.  Any Inventions
Employee has made or conceived  before the effective  date of this Agreement are
listed and described on Exhibit A attached hereto. These items are excluded from
this Agreement.

     13. ASSIGNABILITY.  This Agreement and all rights hereunder are personal to
Employee  and shall not be  assignable  except  in  accordance  with the laws of
descent and  distribution,  and any purported  assignment  in violation  thereof
shall not be valid or binding on InforMax. This Agreement,  however, shall inure
to the benefit  of, and be binding  upon each  successor  of  InforMax,  whether
resulting  from  a  merger  or  consolidation  or to  the  recipient  of  all or
substantially all of the assets of InforMax (and such successor shall thereafter
be deemed the same as InforMax for purposes of this  Agreement).  This Agreement
shall in no way restrict  InforMax's  right to merge,  consolidate,  sell all or
substantially  all of its assets or engage in any business  combination or other
transaction of any nature.

     14. ENTIRE AGREEMENT.  This Agreement,  including Exhibit A, supersedes and
replaces any and all present,  written or oral, agreements of employment between
the parties hereto, and all such agreements are hereby deemed canceled, revoked,
and of no further force or effect.

                                       6
<PAGE>

     15.  ACKNOWLEDGMENT.   Employee  and  InforMax  consider  the  restrictions
contained  in Section 6 of this  Agreement  reasonable,  and it is the desire of
both parties that such  restrictions  and the other provisions of this Agreement
be  enforced  to the fullest  extent  permissible  under the laws and the public
policies  applied  in  each   jurisdiction  in  which   enforcement  is  sought.
Accordingly,  in the event that any such restriction or provision shall be found
to be void or invalid but would be valid if some part  thereof  were  deleted or
the period or area of application reduced,  such restriction or provisions shall
apply  with  such  modification  as shall  be  necessary  to make it  valid  and
effective.  A deletion  resulting  from any  adjudication  shall occur only with
respect to the operation of the provision or a portion  thereof  affected in the
particular  jurisdiction  in which such  adjudication is made, and each court or
other body having jurisdiction with respect to the enforcement of the provisions
of Section 6 of this  Agreement  are hereby  empowered  to modify by  reduction,
rather  than  deletion,  the time  periods  or other  restrictions  referred  to
therein.

     16. MODIFICATION. This Agreement constitutes the entire agreement regarding
employment  of  Employee  by  InforMax  and there are no terms  other than those
stated herein.  No variation  hereof shall be deemed valid unless in writing and
signed by the parties  hereto,  and no  discharge  of the terms  hereof shall be
deemed valid unless by full  performance  by the parties hereto and by a writing
signed by the parties  hereto.  No waiver by either  party of any  provision  or
condition  of this  Agreement  by him or it to be  performed  shall be  deemed a
waiver of similar or dissimilar  provisions  and  conditions at the same time or
any prior or subsequent time.

     17. NOTICES. Any notice,  statement,  report, request or demand required or
permitted  to be  given by this  Agreement  shall be in  writing,  and  shall be
sufficient if addressed and sent by certified mail, return receipt requested, to
the parties at the  addresses set forth above or at such other place that either
party may designate by notice to the other.

     18. EQUITABLE  RELIEF/PAYMENT  OF FEES. The parties to this Agreement agree
that each of them shall be entitled,  in addition to any other remedies they may
have under this  Agreement,  at law, or otherwise,  to immediate  injunctive and
other equitable relief to prevent or curtail any breach of this Agreement. .

     19.  GOVERNING  LAW.  This  Agreement  shall be governed by the laws of the
State of Maryland  (regardless  of the laws that might  otherwise  govern  under
applicable principles or conflicts of law) as to all matters,  including but not
limited to matters of validity, construction, effect, performance and remedies.

     20. COUNTERPARTS.  This Agreement may be executed in counterparts,  each of
which shall be deemed an original,  but which together shall  constitute one and
the same instrument.

                                       7
<PAGE>

     22. LIMITED AGREEMENT.  This Agreement is intended by the parties to govern
only those rights and obligations  described herein,  and it is not the parties'
intent to abrogate  any other  rights in favor of Employee or InforMax  provided
under Federal or State Law.

     IN WITNESS WHEREOF, the parties have executed this Agreement as of the date
set forth below.

                                InforMax, Inc.

                                By:   /s/ Alexander Titomirov
                                      --------------------------------
                                      Alex Titomirov
                                      Chairman, CEO

                                Date:
                                      --------------------------------

                                Employee

                                By:   /s/ Vadim Babenko
                                      --------------------------------
                                      Vadim Babenko

                                Date: 7/14/00
                                      --------------------------------

                                       8EX-10.22

                                 August 14, 2000

InforMax, Inc.
10th Floor
6010 Executive Boulevard
Rockville, Maryland  20852

Gentlemen:

     This  letter  sets  forth the  commitments  I am making to  InforMax,  Inc.
("InforMax"  or "the  Company") in connection  with an equity  investment in the
Company by Amersham Pharmacia Biotech, Inc. ("APB").

     I agree to continue to serve as Chief Executive  Officer and/or Chairman of
the  Board  of  Directors  of  InforMax,  devoting  at  least a  majority  of my
professional  working time to the business of InforMax,  for a period of two (2)
years from the date of this letter or for eighteen  (18) months from the date of
an initial public offering  ("IPO") by InforMax,  whichever is later;  provided,
that, in no event shall this  commitment  extend beyond three (3) years from the
date  hereof;  and,  provided  further,  that I receive  no less than my current
salary, benefits and Board approved bonuses from time-to-time no less than those
awarded to other senior management.

     I also agree that,  for so long as I am an  officer,  employee or holder of
more than 10% of the outstanding shares of InforMax, and for a period of two (2)
years after I cease to be an officer, employee or holder of more than 10% of the
outstanding  shares of  InforMax,  I will not directly  render  services for any
business  engaged in the business in which InforMax is engaged at the time of my

<PAGE>

termination  or any  business  in which  the  Board of  Directors  has given the
management  of  InforMax  the  approval  to  engage  in as  of  the  date  of my
termination;  provided,  that both parties agree that  RealTimeHealth.com,  Inc.
("RTH")  is not  competitive  with the  Company  and thus  not  covered  by this
provision;  and, provided further, that I am not precluded from investing in any
funds which invest in biotechnology or other companies.

     I also agree that,  for so long as I am an  officer,  employee or holder of
more than 10% of the outstanding  shares of InforMax and for a period of two (2)
years after I cease to be an officer, employee or holder of more than 10% of the
outstanding  shares of InforMax,  I will not,  directly or  indirectly,  hire or
engage  or  attempt  to hire or engage  any  individual  who shall  have been an
employee  of InforMax as of the date I cease to be an officer or employee of the
Company  or at any time  during  the one (1)  year  period  prior to such  date,
whether  for or on my own  behalf or for any  entity in which I have a direct or
indirect interest.

     I acknowledge  that,  prior to and  following the Company's  planned IPO, I
will not sell or attempt to sell any shares of stock, options, warrants or other
equity  interest I have in InforMax for a period of six (6) months from the date
of such IPO;  provided,  that, this commitment  shall not restrict my ability to
sell any such equity interests should the currently-filed S-1 be withdrawn.

     I further  acknowledge  that,  if I breach or  attempt to breach any of the
commitments set forth herein,  (i) InforMax may, for a period of sixty (60) days
after such breach or attempted breach becomes known to InforMax,  seek to enjoin
me from further breaches or attempted breaches, or seek to compel me to

<PAGE>

comply with such commitments by specific  performance,  in addition to any other
remedies  available  in equity or at law;  and (ii) after a period of sixty (60)
days from the time any such breach or attempted breach becomes known to InforMax
or APB,  APB may, if and only if InforMax  has not  successfully  enjoined  such
breach or attempted breach, seek to enjoin me from further breaches or attempted
breaches,  or seek to compel me to comply  with  such  commitments  by  specific
performance, in addition to any other remedies available in equity or at law, as
a third-party beneficiary of the foregoing commitments.

     Nothing   contained   herein  shall  be  interpreted  to  limit  any  other
obligations  I have with  respect  to the  Company's  business  pursuant  to the
Shareholder's   Agreement   dated   September  1,  1999  and  the   Confidential
Information,   Non-Competition,   Non-Solicitation  and  Intellectual   Property
Agreement that I have dated June 22, 1999.

                                             Very truly yours,

                                             /s/ Alexander Titomirov
                                             -----------------------------------
                                             Dr. Alexander Titomirov

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00014-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00014-of-00352.parquet"}]]