Document:

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EXHIBIT 10.78
FORM OF CONVERTIBLE DEBENTURE UNDER SECURITIES PURCHASE AGREEMENT

NEITHER THESE SECURITIES NOR THE SECURITIES INTO WHICH THESE SECURITIES ARE
CONVERTIBLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR
THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM
REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "SECURITIES
ACT"), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN
EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR PURSUANT TO AN
AVAILABLE EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION
REQUIREMENTS OF THE SECURITIES ACT AND IN ACCORDANCE WITH APPLICABLE STATE
SECURITIES LAWS AS EVIDENCED BY A LEGAL OPINION OF COUNSEL TO THE TRANSFEROR TO
SUCH EFFECT, THE SUBSTANCE OF WHICH SHALL BE REASONABLY ACCEPTABLE TO THE
COMPANY. THESE SECURITIES MAY BE PLEDGED IN CONNECTION WITH A BONA FIDE MARGIN
ACCOUNT OR OTHER LOAN SECURED BY SUCH SECURITIES.

                                             ORIGINAL ISSUE DATE: AUGUST 9, 2002

No. CD-[ ]                                                                  $[ ]

                         PEREGRINE PHARMACEUTICALS, INC.
               6% SECURED CONVERTIBLE DEBENTURE DUE AUGUST 8, 2005

                  THIS DEBENTURE is one of a series of duly authorized and
issued debentures of PEREGRINE PHARMACEUTICALS, INC., a corporation organized
under the laws of Delaware (the "COMPANY"), designated as its 6% Series A
Convertible Debentures due August 8, 2005 in the aggregate principal amount of
Three Million Seven Hundred Fifty Thousand Dollars ($3,750,000) (collectively,
the "Debentures").

         FOR VALUE RECEIVED, the Company promises to pay to the order of
[debenture holderinvestor name] or its registered assigns (the "HOLDER") the
principal sum of [investment amount] Dollars ($[ ]) and any additional sums due
pursuant to the terms hereof, on August 8, 2005, or such earlier date as the
Debentures are required or permitted to be repaid as provided hereunder (the
"MATURITY Date"), and to pay interest to the Holder on the principal amount of
this Debenture in accordance with the provisions hereof. This Debenture is
subject to the following additional provisions.

         1. DEFINITIONS. As used in this Debenture, the following terms shall
have the meanings set forth in this Section 1:

         "AFFILIATE" means any Person that, directly or indirectly through one
or more intermediaries, controls or is controlled by or is under common control
with a Person, as such terms are used in and construed under Rule 144 under the
Securities Act.

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         "BANKRUPTCY EVENT" means any of the following events: (a) the Company
or any subsidiary thereof commences a case or other proceeding under any
bankruptcy, reorganization, arrangement, adjustment of debt, relief of debtors,
dissolution, insolvency or Liquidation or similar law of any jurisdiction
relating to the Company or any subsidiary thereof; (b) there is commenced
against the Company or any subsidiary thereof any such case or proceeding that
is not dismissed within 60 days after commencement; (c) the Company or any
subsidiary thereof is adjudicated insolvent or bankrupt or any order of relief
or other order approving any such case or proceeding is entered; (d) the Company
or any subsidiary thereof suffers any appointment of any custodian or the like
for it or any substantial part of its property that is not discharged or stayed
within 60 days; (e) the Company or any subsidiary thereof makes a general
assignment for the benefit of creditors; (f) the Company or any subsidiary
thereof fails to pay, or states that it is unable to pay or is unable to pay,
its debts generally as they become due; (g) the Company or any subsidiary
thereof calls a meeting of its creditors with a view to arranging a composition,
adjustment or restructuring of its debts; or (h) the Company or any subsidiary
thereof, by any act or failure to act, expressly indicates its consent to,
approval of or acquiescence in any of the foregoing or takes any corporate or
other action for the purpose of effecting any of the foregoing.

         "BLOOMBERG" means Bloomberg Financial L.P. (or its successor to
reporting stock prices).

         "BUSINESS DAY" means any day except Saturday, Sunday and any day which
shall be a legal holiday or a day on which banking institutions in the State of
New York are authorized or required by law or other governmental action to
close.

         "CLOSING DATE" shall have the meaning set forth in the Purchase
Agreement.

         "CLOSING PRICE" means, for any date, the price determined by the first
of the following clauses that applies: (a) if the Common Stock is then listed or
quoted on an Eligible Market, the closing bid price per share of the Common
Stock for such date (or the nearest preceding date if there is no such price on
such date) on the Eligible Market on which the Common Stock is then listed or
quoted; (b) if the Common Stock is not then listed or quoted on an Eligible
Market and if prices for the Common Stock are then quoted on the OTC Bulletin
Board, the closing bid price per share of the Common Stock for such date (or the
nearest preceding date if there is no such price on such date) on the OTC
Bulletin Board; (c) if the Common Stock is not then listed or quoted on an
Eligible Market or the OTC Bulletin Board and if prices for the Common Stock are
then reported in the "Pink Sheets" published by the National Quotation Bureau
Incorporated (or a similar organization or agency succeeding to its functions of
reporting prices), the most recent bid price per share of the Common Stock so
reported; or (d) in all other cases, the fair market value of a share of Common
Stock as determined by an independent appraiser selected in good faith by the
Holder.

         "COMMISSION" means the Securities and Exchange Commission.

         "COMMON STOCK" means the Company's Common Stock, $.001 par value per
share, and stock of any other class into which such shares may be reclassified
or changed.

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         "COMMON STOCK EQUIVALENTS" means any securities of the Company or any
Subsidiary (as defined in the Purchase Agreement) which entitle the holder
thereof to acquire Common Stock at any time, including without limitation, any
debt, preferred stock, rights, options, warrants or other instrument that is at
any time convertible into or exchangeable for, or otherwise entitles the holder
thereof to receive, Common Stock or other securities that entitle the holder to
receive, directly or indirectly, Common Stock.

         "COMPANY REDEMPTION PRICE" means the sum of (i) 150% of the outstanding
principal amount of this Debenture plus (ii) all other amounts, interest and
liquidated damages due in respect of this Debentures.

         "CONVERSION DATE" is the date specified in a Conversion Notice to
effect conversions of Debentures under Section 5(a)(i), which date may not be
prior to the date the Holder delivers such Conversion Notice. If no Conversion
Date is specified in a Conversion Notice, then the Conversion Date for such
notice shall be the date that such notice is deemed delivered hereunder.

         "CONVERSION PRICE" means $0.85 (subject to adjustment in accordance
with Section 6(g)).

         "DISTRIBUTION" means, with respect to any Person, the declaration or
payment of any dividends by such Person, or the purchase, redemption, retirement
or other acquisition for value of any of its capital stock or other equity now
or hereafter outstanding, or the making of any distribution of assets to its
stockholders as such whether in cash, assets or in obligations of such Person,
or the allocation or other setting apart of any sum for the payment of any
dividend or distribution on, or for the purchase, redemption, retirement or
other acquisition of any shares of its capital stock, or the making of any other
distribution by reduction of capital or otherwise in respect of any shares of
its capital stock.

         "EFFECTIVE DATE" means the date that the Registration Statement is
first declared effective by the Securities and Exchange Commission.

         "EXCHANGE ACT" means the Securities Exchange Act of 1934, as amended.

         "ELIGIBLE MARKET" means whichever of the New York Stock Exchange, the
American Stock Exchange, the Nasdaq National Market or the Nasdaq SmallCap
Market on which the Common Stock is then listed or quoted.

         "EQUITY CONDITIONS" means, with respect to a specified issuance of
Common Stock, that each of the following conditions is satisfied: (i) the number
of authorized but unissued and otherwise unreserved shares of Common Stock is
sufficient for such issuance; (ii) such shares of Common Stock are registered
for resale by the Holder pursuant to an effective registration statement, and
the prospectus thereunder is available for use by the Holder to sell such
shares, or all such shares may be sold by the Holder without volume restrictions
pursuant to Rule 144(k) under the Securities Act; (iii) the Common Stock is
listed or quoted (and is not suspended from trading) on an Eligible Market and
such shares of Common Stock are approved for listing on such Eligible Market
upon issuance; (iv) such issuance would be permitted in full without violating
Section 5(b)(iii) or the rules or regulations of the Eligible Market on which
such shares are listed or quoted; (v) no Bankruptcy Event has occurred; (vi) no

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public announcement of a pending or proposed Sale Event that has not been
approved by the Required Holders; (viii) the Company is not in default with
respect to any material obligation hereunder or under any other Transaction
Document; or (ix) no Event of Default nor any event that with the passage of
time and without being cured would constitute an Event of Default which has
occurred and not been cured.

         "EVENT OF DEFAULT" means the occurrence of any one or more of the
following events (whatever the reason and whether it shall be voluntary or
involuntary or effected by operation of law or pursuant to any judgment, decree
or order of any court, or any order, rule or regulation of any administrative or
governmental body):

                  (i) any default in the payment of principal or liquidated
damages in respect of any Debentures, as and when the same becomes due and
payable (whether by acceleration or otherwise) or any default in the payment of
interest in respect of any Debentures, within five Business Days of when the
same becomes due and payable;

                  (ii) the Company or any Subsidiary defaults in any of its
obligations under any other debenture or any mortgage, credit agreement or other
facility, indenture agreement, factoring agreement or other instrument under
which there may be issued, or by which there may be secured or evidenced, any
Indebtedness, whether such Indebtedness now exists or is hereafter created, and
such default results in such Indebtedness becoming or being declared due and
payable prior to the date on which it would otherwise become due and payable;

                  (iii) a Bankruptcy Event;

                  (iv) the Company shall fail for any reason to deliver
certificates representing Underlying Shares issuable upon a conversion hereunder
that comply with the provisions hereof prior to the fifth Business Day after the
Conversion Date or the Company shall provide notice to any Holder, including by
way of public announcement, at any time, of its intention not to comply with
requests for conversion of Debentures in accordance with the terms hereof;

                  (v) the Company shall fail for any reason to pay in full the
amount of cash due pursuant to a Buy-In within seven days after notice therefor
is delivered hereunder or shall fail to pay any liquidated damages due pursuant
to the Transaction Documents within seven days of the date of the request for
such payment;

                  (vi) the Company shall fail to have available a sufficient
number of authorized and unreserved shares of Common Stock to issue to such
Holder upon a conversion hereunder;

                  (vii) the Registration Statement shall not have been declared
effective by the Commission on or prior to the 150th day after the Original
Issue Date;

                  (viii) during the Effectiveness Period (as defined in the
Registration Rights Agreement), the effectiveness of the Registration Statement
lapses for any reason or the Holder shall not be permitted to resell Registrable
Securities (as defined in the Registration Rights Agreement) under the
Registration Statement, in either case, for more than five consecutive Trading
Days or an aggregate of eight Trading Days (which need not be consecutive
Trading Days);

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                  (ix) an Event (as defined in the Registration Rights
Agreement) shall not have been cured to the satisfaction of the Holder prior to
the expiration of ten days from the Event Date (as defined in the Registration
Rights Agreement) relating thereto (other than an Event resulting from a failure
of a Registration Statement to be declared effective by the Commission on or
prior to the 150th day after the Original Issue Date, which shall be covered by
clause (vii) above);

                  (x) the Company or any Subsidiary takes any Restricted Action
without the prior written consent of the Required Holders; or

                  (xi) the Company defaults in the timely performance of any
other obligation under the Transaction Documents and such default continues
uncured for a period of five Trading Days after the date on which notice of such
default is first given to the Company by the Holder (it being understood that no
prior notice need be given in the case of a default that cannot reasonably be
cured within five Trading Days).

          "FUNDAMENTAL TRANSACTION" any (i) merger or consolidation of the
Company with or into another Person, (ii) any sale of more than one-half of the
assets of the Company (on an as valued basis) in one or a series of related
transactions, (iii) any tender offer or exchange offer (whether by the Company
or another Person) pursuant to which holders of Common Stock are permitted to
tender or exchange their shares for other securities, cash or property, or (iv)
any reclassification of the Common Stock or any compulsory share exchange
pursuant to which the Common Stock is effectively converted into or exchanged
for other securities, cash or property.

         "INDEBTEDNESs" shall mean the principal amount of, premium, if any,
profit participation, if any, and accrued and unpaid interest on and all other
amounts and costs payable in respect of (a) indebtedness for money borrowed from
others; (b) indebtedness guaranteed, directly or indirectly, in any manner, or
in effect guaranteed, directly or indirectly, in any manner through an
agreement, contingent or otherwise, to supply funds to, or in any other manner
invest in the debtor, or to purchase indebtedness, or to purchase and pay for
property if not delivered or pay for services if not performed, primarily for
the purpose of enabling the debtor to make payment of the indebtedness or to
assure the owners of the indebtedness against loss; (c) all indebtedness secured
by any mortgage, lien, pledge, charge or other encumbrance upon property owned
by the Company; (d) all indebtedness of such person created or arising under any
conditional sale, lease (intended primarily as a financing device) or other
title retention or security agreement with respect to property acquired by the
Company even though the rights and remedies of the seller, lessor or lender
under such agreement or lease in the event of a default may be limited to
repossession or sale of such property; (e); and (f) renewals, extensions and
refundings of any such indebtedness.

         "INTELLECTUAL PROPERTY SECURITY AGREEMENT" means the Intellectual
Security Agreement, dated as of the Original Issuance Date, by and among the
Company and the holders of the Debentures, pursuant to which the obligations of
the Company under the Debentures are secured by the intellectual property of the
Company.

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         "INTEREST PAYMENT DATE" means each Semi-Annual Payment Date, Conversion
Date or the Maturity Date, as applicable.

         "LIEN" means any lien (statutory or otherwise), security interest,
mortgage, deed of trust, priority, pledge, charge, conditional sale, title
retention agreement, financing lease or other encumbrance or similar right of
others, or any agreement to give any of the foregoing.

         "LIQUIDATION" means for any Person, any liquidation, dissolution or
winding-up of such Person, whether voluntary or involuntary, by operation or law
or otherwise.

         "MANDATORY PREPAYMENT AMOUNT" for any Debentures shall equal the sum
of: (i) the greater of (A) the principal amount of Debentures to be prepaid and
any Reinstated Principal (to the extent the Holder returns the Underlying Shares
subject to such Reinstated Principal), plus all accrued and unpaid interest
thereon, and (B) the principal amount of Debentures to be prepaid and the
Reinstated Principal (to the extent the Holder returns the Underlying Shares
subject to such Reinstated Principal), plus all accrued and unpaid interest
thereon, divided by the Conversion Price on the Trading Day immediately
preceding (x) the date of the Event of Default or (y) the date the Mandatory
Prepayment Amount is paid in full, whichever is less, multiplied by the Closing
Price on (x) the date of the Event of Default or (y) the date the Mandatory
Prepayment Amount is paid in full, whichever is greater, and (ii) all other
amounts, costs, expenses and liquidated damages due in respect of such
Debentures.

         "MATERIAL PROPERTY" means any interest in real property, the Collateral
Targeting Agent technologies (as described in the SEC Reports) or any of the
businesses, properties, contracts, agreements or operations of Avid Bioservices,
Inc. (as described in the SEC Reports).

         "ORIGINAL ISSUE DATE" means the date of the first issuance of any
Debentures regardless of the number of transfers of any particular Debenture and
regardless of the number of certificates which may be issued to evidence such
Debentures.

         "PERMITTED INDEBTEDNESS" means equipment leases that would require in
the aggregate for all such leases less than $500,000 of payments over the life
thereof.

         "PERSON" means an individual or corporation, partnership, trust,
incorporated or unincorporated association, joint venture, limited liability
company, joint stock company, government (or an agency or subdivision thereof)
or other entity of any kind.

         "PROCEEDING" means an action, claim, suit, investigation or proceeding
(including, without limitation, an investigation or partial proceeding, such as
a deposition), whether commenced or threatened concerning the interpretation,
enforcement or defense of any transaction contemplated by any Transaction
Document (whether brought against a party hereto or such parties affiliates,
directors, officers, employees or agents).

         "PROPERTY" means any interest in any kind of property or asset, whether
real, personal or mixed, and whether tangible or intangible.

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         "PURCHASE AGREEMENT" means the Securities Purchase Agreement, dated as
of August 9, 2002, to which the Company and the original Holders are parties, as
amended, modified or supplemented from time to time in accordance with its
terms.

         "REGISTRATION RIGHTS AGREEMENT" means the Registration Rights
Agreement, dated as of August 9, 2002, to which the Company and the original
Holders are parties, as amended, modified or supplemented from time to time in
accordance with its terms.

         "REGISTRATION STATEMENT" means a registration statement meeting the
requirements of the Registration Rights Agreement and covering the resale of,
among other things, all Underlying Shares by the Holders, who shall be named as
"selling stockholders" thereunder.

         "REINSTATED PRINCIPAL" means the principal amount of Debentures
converted during the ten Trading Days preceding the delivery of an Event of
Default Notice, for which the Company issued or was obligated to issue
Underlying Shares to the Holder.

         "RESTRICTED ACTIONS" the taking by Company or any of its subsidiaries
of any of the following actions"

                  (i) create, incur, assume or suffer to exist any Indebtedness
except Permitted Indebtedness;

                  (ii) create, incur, assume or suffer to exist any guaranty,

                  (iii) create, incur, assume or suffer to exist any Lien, upon
or with respect to any Material Property, now owned or hereafter acquired,
except for Liens pursuant to the Debenture;

                  (iii) create, incur, assume or suffer to exist any obligation
as lessee for the rental or hire of any Material Property, except leases
existing on the Original Issuance Date, and any extensions, supplements or
renewals thereof;

                  (iv) make any loan or advance to any Person or any purchase or
other acquisition of any capital stock, assets, obligations or other securities
of any Person, or any capital contribution to, investment in, or other
acquisition of any interest in, any Person;

                  (v) make any Distribution, except that any subsidiary may make
Distributions to the Company;

                  (vi) sell, lease, assign, transfer or otherwise dispose of any
of its now owned or hereafter acquired Material Property (including, without
limitation, shares of stock and indebtedness, receivables and leasehold
interests), except in the ordinary course of business consistent with past
practices;

                  (vii) sell, lease, assign or otherwise dispose of any Property
to any Affiliate; (a) merge into or consolidate with or purchase or acquire
Property from any Affiliate; or (b) enter into any other transaction directly or
indirectly with or for the benefit of any Affiliate (including, without
limitation, guaranties and assumption of obligations of any Affiliate); provided
that; any Affiliate who is an individual may serve as a director, officer or
employee of the Company or any Subsidiary and receive reasonable compensation
for his or her services in such capacity;

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                  (viii) merge or consolidate with, or sell, assign, lease or
otherwise dispose of (whether in one transaction or in a series of related
transactions) all or substantially all of its assets (whether now owned or
hereafter acquired) to, any Person, or acquire all or substantially all of the
assets or the business of any Person (or enter into any agreement to do any of
the foregoing);

                  (ix) enter into any agreement with respect to the foregoing
provisions (i) through (viii); or

                  (x) enter into any agreement with respect to a Sale Event.

         "REQUIRED HOLDERS" mean the holders of Debentures owning more than 90%
of the aggregate outstanding principal amount of all the Debentures issued by
the Company under the Purchase Agreement.

         "SALE EVENT" means the occurrence of any of the following with respect
to the Company or any Subsidiary (as defined in the Purchase Agreement),
including Avid Bioservices, Inc.,: (i) the sale of all or substantially all of
its assets in one or a series of related transactions, (ii) an acquisition after
by a Person or "group" (as described in Rule 13d-5(b)(1) promulgated under the
Exchange Act) of effective control (whether through legal or beneficial
ownership of capital stock, by contract or otherwise) of in excess of 33% of its
voting securities, (iii) a replacement at one time or over time of more than
one-half of the members of its board of directors which is not approved by a
majority of those individuals who are members of the board of directors on the
date hereof (or by those individuals who are serving as members of the board of
directors on any date whose nomination to the board of directors was approved by
a majority of the members of the board of directors who are members on the date
hereof); provided that the foregoing shall not apply to any Subsidiary so long
as such Subsidiary is wholly-owned by the Company, (iv) the merger or
consolidation of it with or into another entity that is not wholly-owned by the
Company in one or a series of related transactions, or (v) the execution by the
Company of an agreement to which the Company is a party or by which it is bound,
providing for any of the events set forth above in (i), (ii), (iii) or (iv)
above.

         "SECURITIES ACT" means the Securities Act of 1933, as amended.

         "SECURITY AGREEMENT" means the Security Agreement, dated as of the
Original Issuance Date, by and among the Company and the holders of the
Debentures, pursuant to which the obligations of the Company under the
Debentures are secured by the assets of the Company.

         "SEMI-ANNUAL PAYMENT DATE" means each of June 30 and December 31,
except if such date is not a Trading Day, in which case such Semi-Annual Payment
Date shall be the next succeeding Trading Day.

         "STRATEGIC TRANSACTION" means a transaction or relationship in which
the Company issues shares of Common Stock to a Person which is, itself or
through its subsidiaries, an operating company in a business synergistic with
the business of the Company, whose business consists primarily of manufacturing,

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research, developing, or selling pharmaceutical products and in which the
Company receives material benefits in addition to the investment of funds (such
Person, a "STRATEGIC COMPANY"), but shall not include a transaction in which the
Company is issuing securities primarily for the purpose of raising capital or to
a Person whose primary business is investing in securities. The parties agree
that the issuance by the Company of Common Stock in connection with the
Company's licensing of technology to or from a Strategic Company if (i) such
arrangement is approved by the board of directors of the Company, (ii) such
transaction is a bona fide, arms-length transaction to a third party
unaffiliated with the Company or any of its Affiliates, (iii) the Common Stock
at issue may not be registered for resale until 60 Trading Days following the
Effective Date (plus such number of Trading Days during such period when the
Registration Statement may not be used by the Purchasers for the resale of the
shares of Common Stock), (iv) such Strategic Company is not in the primary
business of investing in securities, and (v) such Strategic Company purchases
the Common Stock, for cash, at a price equal to or greater than average of the
Closing Prices of the Common Stock for the five Trading Days immediately
preceding date closing date of the issuance of the Common Stock shall be deemed
a Strategic Transaction.

         "TRADING DAY" means (i) a day on which the Common Stock is traded on an
Eligible Market, or (ii) if the Common Stock is not listed on an Eligible
Market, a day on which the Common Stock is traded in the over the counter
market, as reported by the OTC Bulletin Board, or (iii) if the Common Stock is
not quoted on the OTC Bulletin Board, a day on which the Common Stock is quoted
in the over the counter market as reported by the National Quotation Bureau
Incorporated (or any similar organization or agency succeeding its functions of
reporting prices); provided, that in the event that the Common Stock is not
listed or quoted as set forth in (i), (ii) and (iii) hereof, then Trading Day
shall mean a Business Day.

         "TRANSACTION DOCUMENTS" shall have the meaning set forth in the
Purchase Agreement.

         "UNDERLYING SHARES" means, collectively, the Common Stock issuable upon
conversion of Debentures in accordance with the terms hereof.

         "VWAP" means, with respect to any date of determination, the daily
volume weighted average price (as reported by Bloomberg using the VAP function)
of the Common Stock on such date of determination, or if there is no such price
on such date of determination, then the daily volume weighted average price on
the date nearest preceding such date.

         "WARRANTS" shall have the meaning set forth in the Purchase Agreement.

         "ZLP PURCHASE AGREEMENT" means the Securities Purchase Agreement, dated
as of August 9, 2002, between the Company and ZLP Master Fund, Ltd. ("ZLP"), as
amended, modified or supplemented from time to time in accordance with its
terms, pursuant to which ZLP will purchase from the Company shares of Common
Stock and common stock purchase warrants similar to the Warrants and the
Adjustment Warrants, and have the right to required the Company to register the
Common Stock so purchased and shares of common stock issuable upon exercise of
all common stock purchase warrants pursuant to a registration rights agreement
similar to the Registration Rights Agreement.

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         2. INTEREST.

                  (a) The Company shall pay interest to the Holder on the
aggregate unconverted and then outstanding principal amount of this Debenture
(including any interest added to such principal in accordance with this Section
2) at the rate of 6% per annum, payable in arrears on each Interest Payment
Date. Interest shall be calculated on the basis of a 360-day year and shall
accrue daily commencing on the Original Issue Date (regardless of the number of
transfers of the Debenture).

                  (b) Subject to the conditions and limitations set forth below,
the Company shall pay interest under this Debenture in cash

                  (c) If the Company fails for any reason to pay interest in
cash by the Delivery Date, any Holder may (but shall not be required to) treat
such interest as if it had been added to the principal amount of this Debenture
as of such Delivery Date.

                  (d) Any interest to be paid in cash hereunder that are not
paid by the Delivery Date and not added to the principal amount of the Debenture
shall continue to accrue and shall entail a late fee, which must be paid in
cash, at the rate of 15% per annum or the lesser rate permitted by applicable
law (such fees to accrue daily, from the date such dividend is due hereunder
through and including the date of payment).

         3. REGISTRATION OF DEBENTURES. The Company shall register the
Debentures upon records to be maintained by the Company for that purpose (the
"DEBENTURE REGISTER") in the name of each record holder thereof from time to
time. The Company may deem and treat the registered Holder of this Debenture as
the absolute owner hereof for the purpose of any conversion hereof or any
payment of interest hereon, and for all other purposes, absent actual notice to
the contrary.

         4. REGISTRATION OF TRANSFERS AND EXCHANGES. The Company shall register
the transfer of any portion of this Debenture in the Debenture Register upon
surrender of this Debenture to the Company at its address for notice set forth
herein. Upon any such registration or transfer, a new debenture, in
substantially the form of this Debenture (any such new debenture, a "NEW
DEBENTURE"), evidencing the portion of this Debenture so transferred shall be
issued to the transferee and a New Debenture evidencing the remaining portion of
this Debenture not so transferred, if any, shall be issued to the transferring
Holder. The acceptance of the New Debenture by the transferee thereof shall be
deemed the acceptance by such transferee of all of the rights and obligations of
a holder of a Debenture. This Debenture is exchangeable for an equal aggregate
principal amount of Debentures of different authorized denominations, as
requested by the Holder surrendering the same. No service charge or other fee
will be imposed in connection with any such registration of transfer or
exchange. Transfers of this Debenture and the Underlying Shares are governed by
Section 4.1 of the Purchase Agreement.

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         5. CONVERSION.

                  (a) (i) AT THE OPTION OF THE HOLDER. All or any portion of the
principal amount of this Debenture then outstanding shall be convertible into
Common Stock (subject to the limitations set forth in Section 5(b)), at the
option of the Holder, at any time and from time to time from and after the
Original Issue Date. Holders shall effect conversions under this Section 5(a)(i)
by delivering the Company with a written notice in the form attached hereto as
EXHIBIT A (a "CONVERSION NOTICE") together with a schedule in the form of
SCHEDULE 1 attached hereto (the "CONVERSION SCHEDULE"). The number of Underlying
Shares issuable upon any conversion hereunder shall (subject to the limitations
of Section 5(b)) equal the outstanding principal amount of this Debenture to be
converted divided by the Conversion Price.

                      (ii) AUTOMATIC CONVERSION. Subject to this Section
5(a)(ii), if after the Effective Date, the VWAP for 20 consecutive Trading Days
(such 20 consecutive Trading Day period is hereinafter referred to as the
"DETERMINATION PERIOD") equals or exceeds $2.50 (as adjusted for stock splits,
stock dividends, stock combinations and other similar transactions) (the
"THRESHOLD PRICE") then the outstanding principal amount of the Debentures (and
any accrued and unpaid interest thereunder), subject to the limitations set
forth herein and in Section 5(b), shall be automatically, without any action on
the part of the Company or the Holder, converted, at the Conversion Ratio, into
shares of Common Stock. Such Underlying Shares issuable pursuant to this Section
5(a)(ii) shall be delivered to the Holders within three Trading Days following
the first date in accordance with Section 5(c) that the Threshold Price is met
for 20 consecutive Trading Days. The Debenture shall only be converted pursuant
to this Section 5(a)(ii) if, during the period from the beginning of the
Determination Period used to determine whether the Threshold Price has been met
through and including the third Trading Day following such Determination Period,
the following shall be true: (i) the VWAP shall have equaled or exceeded the
Threshold Price, (ii) the Company shall have honored all conversion notices from
the Holders, (iii) the Equity Conditions have been satisfied with respect to any
and all of the Underlying Shares then issuable upon conversion in full of all
outstanding principal amount of the Debenture at all times, and not breached as
a result of the conversions under this Debenture. If any of the foregoing
conditions shall cease to be satisfied at any time during the required period,
or if the Company shall fail to deliver the Underlying Shares to the Holders
within three Trading Days following the Determination Period, then the
outstanding principal amount of the Debentures shall not be automatically
converted pursuant to this Section 5(a)(ii), until all of the conditions set
forth herein have been satisfied.

                  (b) CERTAIN CONVERSION RESTRICTIONS.

                      (i) Notwithstanding anything to the contrary contained
herein, the number of shares of Common Stock that may be acquired by a Holder
upon any conversion of Debentures (or otherwise in respect hereof) shall be
limited to the extent necessary to insure that, following such conversion (or
other issuance), the total number of shares of Common Stock then beneficially
owned by such Holder and its affiliates and any other Persons whose beneficial
ownership of shares of Common Stock would be aggregated with such Holder's for
purposes of Section 13(d) of the Exchange Act, does not exceed 4.999% of the
total number of issued and outstanding shares of Common Stock (including for
such purpose the shares of Common Stock issuable upon such conversion). For such

                                      -11-
<PAGE>

purposes, beneficial ownership shall be determined in accordance with Section
13(d) of the Exchange Act and the rules and regulations promulgated thereunder.
Each delivery of a Conversion Notice hereunder will constitute a representation
by the applicable Holder that it has evaluated the limitation set forth in this
paragraph and determined that issuance of the full number of Underlying Shares
issuable in respect of such Conversion Notice does not violate the restriction
contained in this paragraph. This provision shall not restrict the number of
shares of Common Stock which a Holder may receive or beneficially own in order
to determine the amount of securities or other consideration that such Holder
may receive in the event of a merger, sale or other business combination or
reclassification involving the Company as contemplated herein.

                      (ii) Notwithstanding anything to the contrary contained
herein, the number of shares of Common Stock that may be acquired by a Holder
upon any conversion of Debentures (or otherwise in respect hereof) shall be
limited to the extent necessary to insure that, following such conversion (or
other issuance), the total number of shares of Common Stock then beneficially
owned by such Holder and its affiliates and any other Persons whose beneficial
ownership of shares of Common Stock would be aggregated with such Holder's for
purposes of Section 13(d) of the Exchange Act, does not exceed 9.999% of the
total number of issued and outstanding shares of Common Stock (including for
such purpose the shares of Common Stock issuable upon such conversion). For such
purposes, beneficial ownership shall be determined in accordance with Section
13(d) of the Exchange Act and the rules and regulations promulgated thereunder.
Each delivery of a Conversion Notice hereunder will constitute a representation
by the applicable Holder that it has evaluated the limitation set forth in this
paragraph and determined that issuance of the full number of Underlying Shares
issuable in respect of such Conversion Notice does not violate the restriction
contained in this paragraph. This provision shall not restrict the number of
shares of Common Stock which a Holder may receive or beneficially own in order
to determine the amount of securities or other consideration that such Holder
may receive in the event of a merger, sale or other business combination or
reclassification involving the Company as contemplated herein.

                      (iii) If the Company has not previously obtained
Shareholder Approval (as defined below), then the Company may not issue in
excess of the Issuable Maximum upon conversions of the Debentures. The "ISSUABLE
MAXIMUM" means a number of shares equal to 22,054,931, less: (i) shares of
Common Stock issued pursuant to the Purchase Agreement, (ii) shares of Common
Stock previously issued upon exercise of the Warrants, (iii) Underlying Shares
previously issued upon conversion of Debentures and payment of interest thereon
in Dividend Shares, (iv) any issuance of shares of Common Stock to an Approved
Purchaser (as defined in the Purchase Agreement) subsequent to the Original
Issue Date pursuant to the Company's Registration Statement No. 333-71086, and
(v) shares of Common Stock issued pursuant to the ZLP Purchase Agreement (and
the transactions contemplated thereby). Each Holder shall be entitled to a
portion of the Issuable Maximum equal to the quotient obtained by dividing: (x)
the principal amount of Debentures issued and sold to such Holder on the
Original Issue Date by (y) the aggregate principal amount Debentures issued and
sold by the Company on the Original Issue Date. If any Holder shall no longer
holds Debentures, then such Holder's remaining portion of the Issuable Maximum
shall be allocated pro-rata among the remaining Holders. If on any Conversion
Date: (A) the aggregate number of shares of Common Stock that would then be
issuable upon conversion in full of all then outstanding principal amount of
Debentures would exceed the Issuable Maximum, and (B) the Company shall not have
previously obtained the vote of shareholders, as may be required by the
applicable rules and regulations of the Nasdaq Stock Market (or any successor
entity) applicable to approve the issuance of shares of Common Stock in excess

                                      -12-
<PAGE>

of the Issuable Maximum pursuant to the terms hereof (the "SHAREHOLDER
APPROVAL"), then, the Company shall issue to the converting Holder a number of
shares of Common Stock equal to such Holder's pro-rata portion (which shall be
calculated pursuant to the terms hereof) of the Issuable Maximum and, with
respect to the remainder of the principal amount of Debentures then held by such
Holder for which a conversion would result in an issuance of shares of Common
Stock in excess of such Holder's pro-rata portion (which shall be calculated
pursuant to the terms hereof) of the Issuable Maximum (the "EXCESS PRINCIPAL
AMOUNT "), the applicable Holder shall have the right to require the Company to
either: (1) obtain the Shareholder Approval applicable to such issuance as soon
as is possible, but in any event not later than the 90th day after such request,
or (2) pay cash, in an amount equal to the Excess Principal Amount (and accrued
and unpaid dividends thereon). If a Holder shall have elected the first option
pursuant to the immediately preceding sentence and the Company shall have failed
to obtain the Shareholder Approval on or prior to the 90th day after such
request, then within three (3) days of such 90th day, the Company shall pay cash
to such Holder an amount equal to Excess Principal Amount (and accrued and
unpaid dividends thereon). If the Company fails to pay the Excess Principal
Value in full pursuant to this Section within seven days after the date payable,
the Company will pay interest thereon at a rate of 15% per annum or such lesser
maximum amount that is permitted to be paid by applicable law, to such Holder,
accruing daily from the Conversion Date until such amount, plus all such
interest thereon, is paid in full. Notwithstanding anything herein to the
contrary, if on any date other than a Conversion Date: (A) the aggregate number
of shares of Common Stock that would then be issuable upon conversion in full of
all then outstanding Debentures would exceed the Issuable Maximum, and (B) the
Company shall not have previously obtained the Shareholder Approval, then, the
Holder shall be entitled to require the Company to pay to it in cash an amount
equal to the outstanding principal amount of the Debentures (plus all accrued
and unpaid dividends thereon) then held by such Holder for which a potential
conversion on such date would result in an issuance of shares of Common Stock in
excess of such Holder's pro-rata portion (which shall be calculated pursuant to
the terms hereof) of the Issuable Maximum. The outstanding principal amount of
the Debentures shall be reduced by the Excess Principal Amount upon the Holder's
receipt of the Excess Principal Amount pursuant to the terms hereof. The Company
and the Holder understand and agree that shares of Common Stock issued to and
then held by the Holder as a result of conversions of Debentures shall not be
entitled to cast votes on any resolution to obtain Shareholder Approval pursuant
hereto.

                      (iv) Notwithstanding anything herein to the contrary, the
Company may not issue, agree to issue, or enter into any arrangement pursuant to
which it may issue at any time, shares of Common Stock or Common Stock
Equivalents that would entitle any holder thereof to receive at any time shares
of Common Stock at, in any such case, a price that is less than the Conversion
Price, unless prior to the earlier to occur of the entering into of such
agreement or such issuance, the Company obtains the approval of its shareholders
pursuant to the rules and regulations of the Nasdaq Stock Market, Inc.
("NASDAQ") (including, without limitation, NASD Rules 4350(i), NASD IM-4300,
NASD IM-4310-2, and Rule 4350(i)): for (i) the transactions contemplated by the
Transaction Documents and the ZLP Purchase Agreement, including, without
limitation, the sale, issuance and potential issuance of the securities issued
and issuable thereunder, including the securities issued pursuant to the
Purchase Agreement as well as the shares of Common Stock issuable in accordance
with the Debentures, the Warrants and Adjustment Warrants, (ii) the issuance
under the Transaction Documents and the ZLP Purchase Agreement (and transactions

                                      -13-
<PAGE>

contemplated thereby) of in excess of 19.99% of the shares of Common Stock
outstanding prior to the Original Issuance Date at a price that is less than the
greater of book or market value of the Common Stock, and/or (iii) the potential
issuance of securities of the Company having sufficient voting power to result
in a change of control of the Company as described under the rules of Nasdaq.
The Company understands and agrees that the shares of Common Stock that have
been issued or that may be issued to and then held by any Holder or any of such
Holder's Affiliates may not cast votes on such matters. In the event that the
Company enters into or seeks to enter into a transaction described in this
Section 5(b)(iii), then the Company shall deposit into an escrow account with an
escrow agent (which account and agent shall be reasonably satisfactory to the
Holders) an amount equal to the aggregate outstanding principal amount of
Debentures plus all accrued and unpaid interest thereon plus all liquidated
damages and other amounts payable thereon, which amount shall be paid to the
Holders in the event that the Company fails to obtain the approval of its
stockholders with respect to such transaction.

                  (c) MECHANICS OF CONVERSION. By the third Trading Day after
each Conversion Date, the Company shall issue or cause to be issued and cause to
be delivered to or upon the written order of the Holder and in such name or
names as the Holder may designate a certificate for the Underlying Shares
issuable upon such conversion which, unless required by the Purchase Agreement,
shall be free of all restrictive legends. The Holder, or any Person so
designated by the Holder to receive Underlying Shares, shall be deemed to have
become the holder of record of such Underlying Shares as of the Conversion Date.
If the Company's transfer agent is eligible to participate in the Depositary
Trust Corporation DWAC system and no legends are required to be included on the
certificates representing Underlying Shares pursuant to the Purchase Agreement,
the Company shall, upon request of the Holder, use its best efforts to deliver
Underlying Shares hereunder electronically through the Depository Trust
Corporation or another established clearing corporation performing similar
functions.

                  (d) To effect conversions hereunder, the Holder shall not be
required to physically surrender this Debenture unless the aggregate principal
amount represented by such Debenture is being converted, in which event, the
Holder shall deliver such Debenture promptly to the Company (it being understood
that such delivery is not a condition precedent to the Company's obligations to
deliver Underlying Shares upon such conversion). Conversions hereunder shall
have the effect of lowering the outstanding principal amount represented by such
Debenture in an amount equal to the applicable conversion, which shall be
evidenced by entries set forth in the Conversion Schedule attached as SCHEDULE
I, which will be maintained by the Company and the Holder.

                  (e) The Company's obligations to issue and deliver Underlying
Shares upon conversion of this Debenture in accordance with the terms hereof are
absolute and unconditional, irrespective of any action or inaction by the Holder
to enforce the same, any waiver or consent with respect to any provision hereof,
the recovery of any judgment against any Person or any action to enforce the
same, or any setoff, counterclaim, recoupment, limitation or termination, or any
breach or alleged breach by the Holder or any other Person of any obligation to
the Company or any violation or alleged violation of law by the Holder or any
other Person, and irrespective of any other circumstance which might otherwise
limit such obligation of the Company to the Holder in connection with the
issuance of such Underlying Shares.

                                      -14-
<PAGE>

                  (f) If by the third Trading Day after a Conversion Date the
Company fails to deliver to the Holder such Underlying Shares in such amounts
and in the manner required pursuant to Section 5(a), then the Holder will have
the right to rescind such conversion.

                  (g) If by the third Trading Day after a Conversion Date the
Company fails to deliver to the Holder such Underlying Shares in such amounts
and in the manner required pursuant to Section 5(c), and if after such third
Trading Day the Holder purchases (in an open market transaction or otherwise)
shares of Common Stock to deliver in satisfaction of a sale by such Holder of
the Underlying Shares which the Holder anticipated receiving upon such
conversion (a "BUY-IN"), then the Company shall: (A) pay in cash to the Holder
(in addition to any remedies available to or elected by the Holder) the amount
by which (x) the Holder's total purchase price (including brokerage commissions,
if any) for the shares of Common Stock so purchased exceeds (y) the amount
obtained by multiplying (1) the aggregate number of Underlying Shares that the
Company was required to deliver to the Holder in connection with the conversion
at issue by (2) the Closing Price at the time of the obligation giving rise to
such purchase obligation and (B) at the option of the Holder, either reinstate
the principal amount of Debentures and equivalent number of Underlying Shares
for which such conversion was not timely honored or deliver to the Holder the
number of shares of Common Stock that would have been issued had the Company
timely complied with its conversion and delivery obligations hereunder. For
example, if the Holder purchases shares of Common Stock having a total purchase
price of $11,000 to cover a Buy-In with respect to an attempted conversion of
Debentures with a market price on the date of conversion totaling $10,000, under
clause (A) of the immediately preceding sentence, the Company shall be required
to pay the Holder $1,000. The Holder shall provide the Company written notice
indicating the amounts payable to the Holder in respect of the Buy-In.

                  (h) ADJUSTMENTS TO CONVERSION PRICE. The Conversion Price in
effect on any Conversion Date shall be subject to adjustments in accordance with
this Section 5(h):

                      (i) STOCK DIVIDENDS AND SPLITS. If the Company, at any
time while any Debentures are outstanding, (i) pays a stock dividend on its
shares of Common Stock or otherwise makes a distribution on any class of capital
stock that is payable in shares of Common Stock, (ii) subdivides outstanding
shares of Common Stock into a larger number of shares, or (iii) combines
outstanding shares of Common Stock into a smaller number of shares, then in each
such case the Conversion Price shall be multiplied by a fraction of which the
numerator shall be the number of shares of Common Stock outstanding immediately
before such event and of which the denominator shall be the number of shares of
Common Stock outstanding immediately after such event. Any adjustment made
pursuant to clause (i) of this paragraph shall become effective immediately
after the record date for the determination of stockholders entitled to receive
such dividend or distribution, and any adjustment pursuant to clause (ii) or
(iii) of this paragraph shall become effective immediately after the effective
date of such subdivision or combination.

                      (ii) ADDITIONAL DISTRIBUTIONS. If the Company, at any time
while any Debentures are outstanding, shall distribute to all holders of shares
of Common Stock (and not to Holders) evidences of its indebtedness or assets or
rights or warrants to subscribe for or purchase any security, then in each such
case the Conversion Price at which the principal amount of Debentures shall
thereafter be convertible shall be determined by multiplying the Conversion

                                      -15-
<PAGE>

Price in effect immediately prior to the record date fixed for determination of
stockholders entitled to receive such distribution by a fraction of which the
denominator shall be the Closing Price determined as of the record date
mentioned above, and of which the numerator shall be such Closing Price on such
record date less the then fair market value at such record date of the portion
of such assets or evidence of indebtedness so distributed applicable to one
outstanding Common Share as determined by the Board of Directors in good faith.
In either case the adjustments shall be described in a statement provided to the
Holders of the portion of assets or evidences of indebtedness so distributed or
such subscription rights applicable to one share of Common Stock. Such
adjustment shall be made whenever any such distribution is made and shall become
effective immediately after the record date mentioned above.

                      (iii) SUBSEQUENT EQUITY SALES. If the Company or any
subsidiary thereof, at any time while Debentures are outstanding and during the
period between the Original Issue Date and the 18th month anniversary of the
Effective Date (provided that such period shall be extended by the number of
days in which the Registration Statement is not effective or the prospectus
included in the Registration Statement may not be used by the selling
stockholders thereunder for the resale of the shares of Common Stock registered
thereunder), shall issue shares of Common Stock or Common Stock Equivalents
entitling any Person to acquire shares of Common Stock, at a price per share
less than the Conversion Price (if the holder of the Common Stock or Common
Stock Equivalent so issued shall at any time, whether by operation of purchase
price adjustments, reset provisions, floating conversion, exercise or exchange
prices or otherwise, or due to warrants, options or rights issued in connection
with such issuance, be entitled to receive shares of Common Stock at a price
less than the Conversion Price, such issuance shall be deemed to have occurred
for less than the Conversion Price), then, at the option of the Holder for such
exercises as it shall indicate, the Conversion Price shall be adjusted to equal
the conversion, exchange or purchase price for such Common Stock or Common Stock
Equivalents (including any reset provisions thereof) at issue. Such adjustment
shall be made whenever such Common Stock or Common Stock Equivalents are issued,
and which adjusted Conversion Price shall continue for as long as the Debentures
remain outstanding. The Company shall notify the Holder in writing, no later
than the Trading Day following the issuance of any Common Stock or Common Stock
Equivalent subject to this section, indicating therein the applicable issuance
price, or of applicable reset price, exchange price, conversion price and other
pricing terms.

                           (A) If, at any time while any Debentures are
outstanding, the Company or any subsidiary issues Common Stock Equivalents at a
price per share that floats or resets or otherwise varies or is subject to
adjustment based on market prices of the Common Stock (a "FLOATING PRICE
SECURITY"), then for purposes of applying the preceding paragraph in connection
with any subsequent exercise, the Conversion Price will be determined separately
on each Conversion Date and will be deemed to equal the lowest price per share
at which any holder of such Floating Price Security is entitled to acquire
shares of Common Stock on such Conversion Date (regardless of whether any such
Holder actually acquires any shares on such date).

                           (B) Notwithstanding the foregoing, no adjustment will
be made under this Section 5(h)(iii) as a result of: (i) any grant of an option
or warrant for Common Stock or issuance of any shares of Common Stock upon the
exercise of any options or warrants to employees, officers and directors of or

                                      -16-
<PAGE>

consultants to the Company pursuant to any stock option plan, employee stock
purchase plan or similar plan or consulting arrangement approved by the
Company's board of directors or (ii) any rights or agreements to purchase Common
Stock or Common Stock Equivalents outstanding on the Original Issue Date hereof
and as specified in SCHEDULE 3.1(G) (but not as to any amendments or other
modifications to the number of shares of Common Stock issuable thereunder, the
terms set forth therein, or the exercise price set forth therein) or (iii) the
issuance of shares of Common Stock in connection with a Strategic Transaction or
(iv) the issuance of up to 2,900,000 shares of Common Stock (as adjusted for
stock splits, reverse stock splits, combinations and other similar transactions)
to any Approved Purchaser (as defined in the Purchase Agreement) pursuant to
Registration Statement No. 333-71086 or (v) the issuance of Common Stock
pursuant to the Transaction Documents or the ZLP Purchase Agreement (or the
transactions contemplated thereby).

                      (iv) CALCULATIONS. All calculations under this Section 5
shall be made to the nearest cent or the nearest 1/100th of a share, as the case
may be. The number of shares of Common Stock outstanding at any given time shall
not include shares owned or held by or for the account of the Company, and the
disposition of any such shares shall be considered an issue or sale of Common
Stock.

                      (v) NOTICE OF ADJUSTMENTS. Whenever the Conversion Price
is adjusted pursuant to the terms hereof the Company shall promptly mail to each
Holder, a notice setting forth the Conversion Price after such adjustment and
setting forth a brief statement of the facts requiring such adjustment.

                  (i) CERTAIN FUNDAMENTAL TRANSACTIONS. In case of any
Fundamental Transaction, a Holder shall have the right to do any of the
following: (1) convert its Debentures into the shares of stock and other
securities, cash and property receivable upon or deemed to be held by holders of
shares of Common Stock following such Fundamental Transaction and such Holder
shall be entitled upon such Fundamental Transaction to receive such amount of
securities, cash and property as the shares of Common Stock into which such
Debentures could have been converted immediately prior to such Fundamental
Transaction would have been entitled, or (2)(x) require the surviving entity to
issue debentures in such principal amount equal to the principal amount of the
Debentures held by such Holder prior to such Fundamental Transaction, plus all
other amounts owing thereon, which newly issued debentures shall have identical
terms to the terms of the Debentures and shall be entitled to all of the rights
and privileges of a Holder set forth herein and the agreements pursuant to which
the prepayment was issued, and (y) simultaneously with the issuance of such
convertible debentures shall have the right to convert such shares only into
shares of stock and other securities, cash and property receivable upon or
deemed to be held by holders of shares of Common Stock following such
Fundamental Transaction (the conversion price applicable for the newly issued
convertible debentures shall be based upon the amount of securities, cash and
property that each Common Share would receive in such Fundamental Transaction
and the Conversion Price stated herein) or (3) at the Holder's option and
request, any successor to the Company or surviving entity in such Fundamental
Transaction shall either pay to the Holder the greater of (A) the outstanding
principal amount of the Debentures held by such Holder plus all accrued and
unpaid interest thereon, and (B) the principal amount of the Debenture held by
such Holder, plus all accrued and unpaid interest thereon, divided by the
Conversion Price on the Trading Day immediately preceding (x) the date of prior

                                      -17-
<PAGE>

to such Fundamental Transaction or (y) the date the amount set forth in this
section is paid in full, whichever is less, multiplied by the Closing Price on
(x) the date of the Fundamental Transaction or (y) the date the amount set forth
in this section is paid in full, whichever is greater. Any Fundamental
Transaction shall include such terms so as continue to give the Holders the
right to receive the securities, cash and property set forth in this Section
upon any conversion or redemption following such event. This provision shall
similarly apply to successive such Fundamental Transactions. The rights set
forth herein shall not alter the rights of a Holder set forth in Section 6,
provided, that, a Holder may only exercise the rights set forth herein or the
rights set forth in Section 6 with respect to a single event giving rise to such
rights.

                  (j) RECLASSIFICATIONS; SHARE EXCHANGES. In case of any
reclassification of the shares of Common Stock, or any compulsory share exchange
pursuant to which the shares of Common Stock are converted into other
securities, cash or property (other than compulsory share exchanges which
constitute a Sale Event), the Holders of the Debentures then outstanding shall
have the right thereafter to convert such shares only into the shares of stock
and other securities, cash and property receivable upon or deemed to be held by
holders of shares of Common Stock following such reclassification or share
exchange, and the Holders shall be entitled upon such event to receive such
amount of securities, cash or property as a holder of the number of shares of
Common Stock of the Company into which such shares of Debentures could have been
converted immediately prior to such reclassification or share exchange would
have been entitled. This provision shall similarly apply to successive
reclassifications or share exchanges.

                  (k) NOTICE OF CORPORATE EVENTS. If: (a) the Company shall
declare a dividend (or any other distribution) on the Common Stock, (b) the
Company shall declare a special nonrecurring cash dividend on or a redemption of
the Common Stock, (c) the Company shall authorize the granting to all holders of
Common Stock rights or warrants to subscribe for or purchase any shares of
capital stock of any class or of any rights, (d) the approval of any
stockholders of the Company shall be required in connection with any Sale Event
or Fundamental Transaction, or (e) the Company shall authorize the voluntary or
involuntary dissolution, liquidation or winding up of the affairs of the
Company; then the Company shall file a press release or Current Report on Form
8-K to disclose such occurrence and notify the Holders at their last addresses
as they shall appear upon the stock books of the Company, at least 20 calendar
days prior to the applicable record or effective date hereinafter specified, a
notice stating (x) the date on which a record is to be taken for the purpose of
such dividend, distribution, redemption, rights or warrants, or if a record is
not to be taken, the date as of which the holders of Common Stock of record to
be entitled to such dividend, distributions, redemption, rights or warrants are
to be determined or (y) the date on which any such Sale Event or Fundamental
Transaction is expected to become effective or close, and the date as of which
it is expected that holders of Common Stock of record shall be entitled to
exchange their Common Stock for securities, cash or other property deliverable
upon any such Sale Event or Fundamental Transaction. Holders are entitled to
convert the outstanding principal amount of the Debentures during the 20-day
period commencing the date of such notice to the effective date of the event
triggering such notice.

                  (l) RESERVATION OF COMMON STOCK. The Company covenants that it
will at all times reserve and keep available out of its authorized and unissued
shares of Common Stock solely for the purpose of issuance upon conversion of
Debentures, each as herein provided, free from preemptive rights or any other

                                      -18-
<PAGE>

actual contingent purchase rights of persons other than the Holders, not less
than such number of shares of Common Stock as shall be issuable upon the
conversion of all outstanding principal amount of Debentures. The Company
covenants that all shares of Common Stock that shall be so issuable shall, upon
issue, be duly and validly authorized and issued and fully paid and
nonassessable.

                  (m) FRACTIONAL SHARES. Upon a conversion hereunder the Company
shall not be required to issue stock certificates representing fractions of
shares of Common Stock, but may if otherwise permitted, make a cash payment in
respect of any final fraction of a share based on the Closing Price on the
applicable Conversion Date. If any fraction of an Underlying Share would, except
for the provisions of this Section, be issuable upon a conversion hereunder, the
Company shall pay an amount in cash equal to the Conversion Price multiplied by
such fraction.

                  (n) STAMP TAXES. The issuance of certificates for Common Stock
on conversion of principal amount of this Debenture shall be made without charge
to the Holders thereof for any documentary stamp or similar taxes that may be
payable in respect of the issue or delivery of such certificate, provided that
the Company shall not be required to pay any tax that may be payable in respect
of any transfer involved in the issuance and delivery of any such certificate
upon conversion in a name other than that of the Holder of such Debentures so
converted.

                  (o) NOTICES. Any and all notices or other communications or
deliveries to be provided by the Holders, including, without limitation, any
Holder Conversion Notice, shall be in writing and delivered personally, by
facsimile or sent by a nationally recognized overnight courier service,
addressed to the attention of the Chief Financial Officer of the Company
addressed to Peregrine Pharmaceuticals, Inc., 14272 Franklin Avenue, Tustin,
California 92780, Facsimile No.: (714) 838-5817, attention Chief Financial
Officer, or to such other address or facsimile number as shall be specified in
writing by the Company for such purpose. Any and all notices or other
communications or deliveries to be provided by the Company hereunder shall be in
writing and delivered personally, by facsimile or sent by a nationally
recognized overnight courier service, addressed to each Holder at the facsimile
telephone number or address of such Holder appearing on the books of the
Company, or if no such facsimile telephone number or address appears, at the
principal place of business of the Holder. Any notice or other communication or
deliveries hereunder shall be deemed given and effective on the earliest of (i)
the date of transmission, if such notice or communication is delivered via
facsimile at the facsimile telephone number specified in this Section prior to
6:30 p.m. (New York City time) (with confirmation of transmission), (ii) the
date after the date of transmission, if such notice or communication is
delivered via facsimile at the facsimile telephone number specified in this
Section later than 6:30 p.m. (New York City time) on any date and earlier than
11:59 p.m. (New York City time) on such date (with confirmation of
transmission), (iii) upon receipt, if sent by a nationally recognized overnight
courier service, or (iv) upon actual receipt by the party to whom such notice is
required to be given.

         6. RESTRICTED ACTIONS. Neither the Company nor any subsidiary shall
taken any Restricted Action without the prior written consent of the Required
Holders.

                                      -19-
<PAGE>

         7. PREPAYMENTS.

                  (a) UPON EVENT OF DEFAULT. Upon the occurrence of an Event of
Default, each Holder shall (in addition to all other rights it may have
hereunder or under applicable law), have the right, exercisable at the sole
option of such Holder, and by delivery of a written notice to the Company to
require the Company (an "EVENT OF DEFAULT NOTICE") to prepay all or a portion of
the Debentures then held by such Holder and, at the option of the Holder, all or
a portion of the Reinstated Principal, for an amount, in cash, equal to the
Mandatory Prepayment Amount. The Mandatory Prepayment Amount shall be due and
payable within five Trading Days of the date of the Event of Default Notice. For
purposes of this Section, principal amount of Debentures shall remain
outstanding until such date as the Holder shall have received Underlying Shares
upon a conversion (or attempted conversion) thereof that meets the requirements
hereof. Notwithstanding anything herein to the contrary, upon the occurrence of
a Bankruptcy Event, all outstanding principal and accrued but unpaid interest on
this Debenture shall immediately become due and payable in full in cash, without
any further action by the Holder, and the Company shall immediately be obligated
to pay the Mandatory Prepayment Amount pursuant to this paragraph as if the
Holder had delivered a Event of Default Notice immediately prior to the
occurrence of any such Event of Default. The Holder need not provide and the
Company hereby waives any presentment, demand, protest or other notice of any
kind, and the Holder may immediately and without expiration of any grace period
enforce any and all of its rights and remedies hereunder and all other remedies
available to it under applicable law. Such declaration may be rescinded and
annulled by Holder at any time prior to payment hereunder. No such rescission or
annulment shall affect any subsequent Event of Default or impair any right
consequent thereon.

                  (b) UPON SALE EVENT. The Company shall notify the Holders on
the day that the Company enters into a transaction giving rise to a Sale Event
(such notice, a "COMPANY REDEMPTION NOTICE" and the date such Company Redemption
Notice is received by a Holder, a "COMPANY REDEMPTION DATE"). The Company
Redemption Notice shall describe the Sale Event and state the consideration
being paid in such Sale Event and the date of consummation of the Sale Event. In
addition, on the day that the Company delivers to the Holders a Company
Redemption Notice, the Company shall also issue a press release and file a
Current Report on Form 8-K, in each case disclosing all material terms of the
Sale Event. Concurrent with the closing of the Sale Event (and as a condition
precedent to such closing), the Company shall, redeem, in cash, all outstanding
principal amount of the Debentures which have not previously been redeemed or
for which Conversion Notices shall not have been delivered, at a price equal to
the Company Redemption Price. Notwithstanding the foregoing, a Holder may
convert (and the Company shall honor such conversions in accordance with the
terms hereof) any or all of the outstanding principal amounts of Debentures
subject to a Company Redemption Notice delivered for conversion on or prior to
the Sale Event. Concurrent with the closing of the Sale Event, the Company shall
cause the escrow agent holding the Company Redemption Price to pay to the
Holders the Company Redemption Price, which amount shall be due and payable in
cash, and such payment of the Company Redemption Amount shall be a condition
precedent to the closing of the Sale Event.

                  (c) AT COMPANY'S OPTION. If after the Effective Date, the
Closing Price for ten consecutive Trading Days is less than $1.00 per share (as

                                      -20-
<PAGE>

adjusted for stock splits, stock dividends, stock combinations and other similar
transactions) (the "MINIMUM PRICE"), then the Company may deliver a notice to
the Holders (an "OPTIONAL REPAYMENT NOTICE" and the date such notice is received
by the Holders, the "OPTIONAL REPAYMENT NOTICE DATE") of its irrevocable
election to repay all, but not less than all, of the then aggregate amount of
outstanding Debentures, for an amount, in cash, equal to the Company Redemption
Price. The Company Redemption Amount payable pursuant to this Section 7(c) is
due in full on the tenth Trading Day following the Optional Repayment Notice
Date. The Company may only deliver an Optional Repayment Notice if from the
first of the ten Trading Days utilized to determine whether the Minimum Price
has been so met through and including the tenth Trading Day following the
Optional Repayment Notice Date each of the following shall be true: (i) the
Closing Price shall be less than the Minimum Price, (ii) the Company shall have
duly honored all conversions and redemptions scheduled to occur or occurring by
virtue of one or more Conversion Notices prior to the Optional Repayment Due
Date, (iii) the Equity Conditions shall have been satisfied at all times. If any
of the foregoing conditions shall cease to be satisfied at any time during the
required period, or if the Company shall fail to pay the Optional Repayment
Amount in full by the Optional Repayment Due Date, then the Optional Repayment
Notice shall be null and void, ab initio, and the Company may not deliver any
subsequent Optional Repayment Notices. The Holder may convert any portion of
this Debenture prior to the Optional Repayment Due Date. The Company covenants
and agrees that it will honor all Conversion Notices tendered from the time of
delivery of the Optional Repayment Notice through the Optional Repayment Due
Date.

         8. RANKING. This Debenture ranks pari passu to all other Debentures now
or hereafter issued pursuant to the Transaction Documents. No Indebtedness of
the Company is senior to this Debenture in right of payment, whether with
respect of interest, damages or upon Liquidation or dissolution or otherwise.

         9. SECURED OBLIGATION. The payment obligations under this Debenture are
secured pursuant to the Security Agreement and Intellectual Property Security
Agreement. Such agreements will terminate upon the earlier to occur of the
following: (i) with respect to the Holder upon the date on which all payments
hereunder have been made in full or the Debenture has otherwise been converted
pursuant to the terms hereof and (ii) the 21st day following (but not including)
the date that the Closing Price exceeds $1.25 per share (as adjusted for stock
splits, stock dividends, stock combinations and other similar transactions) for
20 consecutive Trading Days and the Equity Conditions shall have been satisfied
at all times during such 20 consecutive Trading Days.

         10. MISCELLANEOUS.

                  (a) This Debenture shall be binding on and inure to the
benefit of the parties hereto and their respective successors and assigns. This
Debenture may be amended only in writing signed by the Company and the Holder
and their successors and assigns.

                                      -21-
<PAGE>

                  (b) Subject to Section 9(a), above, nothing in this Debenture
shall be construed to give to any person or corporation other than the Company
and the Holder any legal or equitable right, remedy or cause under this
Debenture. This Debenture shall inure to the sole and exclusive benefit of the
Company and the Holder.

                  (c) All questions concerning the construction, validity,
enforcement and interpretation of this Debenture shall be governed by and
construed and enforced in accordance with the internal laws of the State of New
York, without regard to the principles of conflicts of law thereof. Each party
agrees that all Proceedings shall be commenced exclusively in the state and
federal courts sitting in the City of New York, Borough of Manhattan (the "NEW
YORK COURTS"). Each party hereto hereby irrevocably submits to the exclusive
jurisdiction of the New York Courts for any proceeding, and hereby irrevocably
waives, and agrees not to assert in any Proceeding, any claim that it is not
personally subject to the jurisdiction of any New York Court or that a New York
Court is an inconvenient forum for such Proceeding. Each party hereto hereby
irrevocably waives personal service of process and consents to process being
served in any such Proceeding by mailing a copy thereof via registered or
certified mail or overnight delivery (with evidence of delivery) to such party
at the address in effect for notices to it under this Debenture and agrees that
such service shall constitute good and sufficient service of process and notice
thereof. Nothing contained herein shall be deemed to limit in any way any right
to serve process in any manner permitted by law. Each party hereto hereby
irrevocably waives, to the fullest extent permitted by applicable law, any and
all right to trial by jury in any legal Proceeding. If either party shall
commence a Proceeding, then the prevailing party in such Proceeding shall be
reimbursed by the other party for its attorney's fees and other costs and
expenses incurred with the investigation, preparation and prosecution of such
Proceeding.

                  (d) The headings herein are for convenience only, do not
constitute a part of this Debenture and shall not be deemed to limit or affect
any of the provisions hereof.

                  (e) In case any one or more of the provisions of this
Debenture shall be invalid or unenforceable in any respect, the validity and
enforceability of the remaining terms and provisions of this Debenture shall not
in any way be affected or impaired thereby and the parties will attempt in good
faith to agree upon a valid and enforceable provision which shall be a
commercially reasonable substitute therefor, and upon so agreeing, shall
incorporate such substitute provision in this Debenture.

                  (f) No provision of this Debenture may be waived or amended
except in a written instrument signed, in the case of an amendment, by the
Company and the Holder or, or, in the case of a waiver, by the Holder. No waiver
of any default with respect to any provision, condition or requirement of this
Debenture shall be deemed to be a continuing waiver in the future or a waiver of
any subsequent default or a waiver of any other provision, condition or
requirement hereof, nor shall any delay or omission of either party to exercise
any right hereunder in any manner impair the exercise of any such right.

                  (g) Any cash amounts due from the Company under this
Debenture, including, interest, liquidated damages and redemption amounts, which
is not paid on the date such payment is due to be paid shall continue to accrue
and shall entail a late fee, which must be paid in cash, at the rate of 15% per
annum or the lesser rate permitted by applicable law (such fees to accrue daily,
from the date such amount is due hereunder through and including the date of
payment in full of such amount).

                                      -22-
<PAGE>

                  (h) If it shall be found that any interest due hereunder shall
violate applicable laws governing usury, the applicable rate of interest due
hereunder shall be reduced to the maximum permitted rate of interest under such
law.

                  (i) Except pursuant to the terms of this Debenture, the
outstanding principal amount and interest under this Debenture may not be
prepaid by the Company without the prior written consent of the Holder.

                   [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK
                             SIGNATURE PAGE FOLLOWS]

                                      -23-
<PAGE>

         IN WITNESS WHEREOF, the Company has caused this Debenture to be duly
executed by a duly authorized officer as of the date first above indicated.

                         PEREGRINE PHARMACEUTICALS, INC.

                                             By:
                                                --------------------------------
                                                Name:  Paul Lytle
                                                Title: V.P. Finance & Accounting

                                      -24-
<PAGE>

                                    EXHIBIT A

                                CONVERSION NOTICE

(To be Executed by the Registered Holder
in order to convert Debentures)

                  The undersigned hereby elects to convert the principal amount
of Debenture indicated below, into shares of Common Stock of Peregrine
Pharmaceuticals, Inc. as of the date written below. If shares are to be issued
in the name of a Person other than undersigned, the undersigned will pay all
transfer taxes payable with respect thereto and is delivering herewith such
certificates and opinions as reasonably requested by the Company in accordance
therewith. No fee will be charged to the Holder for any conversion, except for
such transfer taxes, if any. All terms used in this notice shall have the
meanings set forth in the Debenture.

Conversion calculations:           _____________________________________________
                                   Date to Effect Conversion

                                   _____________________________________________
                                   Principal amount of Debenture owned prior to
                                   conversion

                                   _____________________________________________
                                   Principal amount of Debenture to be Converted

                                   _____________________________________________
                                   Principal amount of Debenture remaining after
                                   Conversion

                                   _____________________________________________
                                   Number of shares of Common Stock to be Issued

                                   Conversion Price_____________________________

                                   Signature____________________________________

                                   Name_________________________________________

                                   Address______________________________________

                  By the delivery of this Conversion Notice, the Holder
represents and warrants to the Company that its ownership of the shares of
Common Stock does not exceed the restrictions set forth in Sections 5(b) of the
Debenture.

<PAGE>

                                   SCHEDULE 1

                               CONVERSION SCHEDULE

6% Convertible Debentures, due August 8, 2005, in the aggregate principal amount
of $_______ issued by Peregrine Pharmaceuticals, Inc. This Conversion Schedule
reflects conversions made under the above referenced Debentures.

--------------  --------------  --------------  --------------  --------------
Date of         Amount of       Aggregate       Applicable      Mandatory
Conversion      Conversion      Principal       Conversion      Prepayment
                                Amount          Price           Amount
                                Remaining
                                Subsequent to
                                Conversion
--------------  --------------  --------------  --------------  --------------
--------------  --------------  --------------  --------------  --------------
--------------  --------------  --------------  --------------  --------------
--------------  --------------  --------------  --------------  --------------
--------------  --------------  --------------  --------------  --------------
--------------  --------------  --------------  --------------  --------------
--------------  --------------  --------------  --------------  --------------
--------------  --------------  --------------  --------------  --------------
--------------  --------------  --------------  --------------  --------------
--------------  --------------  --------------  --------------  --------------
--------------  --------------  --------------  --------------  --------------
--------------  --------------  --------------  --------------  --------------
--------------  --------------  --------------  --------------  --------------
--------------  --------------  --------------  --------------  --------------<PAGE>
EXHIBIT 10.79
FORM OF REGISTRATION RIGHTS AGREEMENT UNDER SECURITIES PURCHASE AGREEMENT

                          REGISTRATION RIGHTS AGREEMENT

                  This Registration Rights Agreement (this "AGREEMENT") is made
and entered into as of August 9, 2002, by and among Peregrine Pharmaceuticals,
Inc., a Delaware corporation (the "COMPANY"), and the investors signatory hereto
(each a "PURCHASER" and collectively, the "PURCHASERS").

                  This Agreement is made pursuant to the Securities Purchase
Agreement, dated as of the date hereof among the Company and the Purchasers (the
"PURCHASE AGREEMENT").

                  The Company and the Purchasers hereby agree as follows:

         1. DEFINITIONS. Capitalized terms used and not otherwise defined herein
that are defined in the Purchase Agreement shall have the meanings given such
terms in the Purchase Agreement. As used in this Agreement, the following terms
shall have the following meanings:

                  "COMMON SHARES" means the shares of Common Stock issued or
issuable to the Purchasers pursuant to the Purchase Agreement.

                  "COMMON STOCK" means the Common Stock, $.001 par value per
share, of the Company.

                  "COMMON STOCK WARRANTS" mean the Common Stock Warrants issued
to the Purchasers pursuant to the Purchase Agreement.

                  "DEBENTURES" means the 6% Secured Convertible Debentures, in
the aggregate principal amount of $[ ], issued to the Purchasers pursuant to the
Purchase Agreement.

                  "DEBENTURE WARRANTS" mean the Debenture Warrants issued to the
Purchasers pursuant to the Purchase Agreement.

                  "EFFECTIVE DATE" means the date on which a Registration
Statement is declared effective by the Commission.

                  "EFFECTIVENESS DATE" means, (a) with respect to the initial
Registration Statement required to be filed hereunder, the earlier of (i) the
90th day following the Closing Date and (ii) the third Trading Day following the
date on which the Company is notified by the Commission that such Registration
Statement will not be reviewed or is no longer subject to further review and
comments, and (b) with respect to any additional Registration Statements that
may be required pursuant to SECTION 2(C) or SECTION 2(D) the earlier of (i) the
90th day following the date on which the Company first knows, or reasonably
should have known, that such additional Registration Statement is required under
such Section and (ii) the third Trading Day following the date on which the
Company is notified by the Commission that such Registration Statement will not
be reviewed or is no longer subject to further review and comments.

                  "EFFECTIVENESS PERIOD" shall have the meaning set forth in
Section 2(a).

<PAGE>

                  "FILING DATE" means: (a) with respect to the initial
Registration Statement required to be filed hereunder, the 30th day following
the Closing Date, and (b) with respect to any additional Registration Statements
that may be required pursuant to Section 2(c), the 30th day following the date
on which the Company first knows, or reasonably should have known, that such
additional Registration Statement is required under such Section.

                  "HOLDER" or "HOLDERS" means the holder or holders, as the case
may be, from time to time of Registrable Securities.

                  "INDEMNIFIED PARTY" shall have the meaning set forth in
Section 5(c).

                  "INDEMNIFYING PARTY" shall have the meaning set forth in
Section 5(c).

                  "LOSSES" shall have the meaning set forth in Section 5(a).

                  "PROCEEDING" means an action, claim, suit, investigation or
proceeding (including, without limitation, an investigation or partial
proceeding, such as a deposition), whether commenced or threatened.

                  "PROSPECTUS" means the prospectus included in a Registration
Statement (including, without limitation, a prospectus that includes any
information previously omitted from a prospectus filed as part of an effective
registration statement in reliance upon Rule 430A promulgated under the
Securities Act), as amended or supplemented by any prospectus supplement, with
respect to the terms of the offering of any portion of the Registrable
Securities covered by a Registration Statement, and all other amendments and
supplements to the Prospectus, including post-effective amendments, and all
material incorporated by reference or deemed to be incorporated by reference in
such Prospectus.

                  "REGISTRABLE SECURITIES" means the Common Shares, Underlying
Shares and Warrant Shares, together with any securities issued or issuable upon
any stock split, dividend or other distribution, recapitalization or similar
event with respect to the foregoing.

                  "REGISTRATION STATEMENT" means each of the following: (a) an
initial registration statement which is required to register the resale of not
less than 125% of the Registrable Securities measured on the Closing Date, the
Filing Date or the date of request for acceleration of such registration
statement (whichever yields the highest number of shares), (b) each additional
registration statement, if any, contemplated by Section 2(c), and (c) including,
in each case, the Prospectus, amendments and supplements to each such
registration statement or Prospectus, including pre- and post-effective
amendments, all exhibits thereto, and all material incorporated by reference or
deemed to be incorporated by reference in such registration statement.

                  "RULE 144" means Rule 144 promulgated by the Commission
pursuant to the Securities Act, as such Rule may be amended from time to time,
or any similar rule or regulation hereafter adopted by the Commission having
substantially the same purpose and effect as such Rule.

                                      -2-
<PAGE>

                  "RULE 415" means Rule 415 promulgated by the Commission
pursuant to the Securities Act, as such Rule may be amended from time to time,
or any similar rule or regulation hereafter adopted by the Commission having
substantially the same purpose and effect as such Rule.

                  "RULE 424" means Rule 424 promulgated by the Commission
pursuant to the Securities Act, as such Rule may be amended from time to time,
or any similar rule or regulation hereafter adopted by the Commission having
substantially the same purpose and effect as such Rule.

                  "UNDERLYING SHARES" means the shares of Common Stock issuable
upon conversion of the Debentures.

                  "SPECIAL COUNSEL" means legal counsel to a Purchaser who will
be reimbursed by the Company pursuant to Section 4.

                  "WARRANT SHARES" means the shares of Common Stock issuable
upon exercise of the Warrants.

                  "WARRANTS" mean the Common Stock Warrants, the Debenture
Warrants and Adjustment Warrant issued or issuable under the Purchase Agreement.

         2. REGISTRATION.

                  (a) On or prior to each Filing Date, the Company shall prepare
and file with the Commission a Registration Statement covering the resale of all
Registrable Securities required to be included in such Registration Statement
for an offering to be made on a continuous basis pursuant to Rule 415. Each
Registration Statement shall be on Form S-3 (except if the Company is not then
eligible to register for resale the Registrable Securities on Form S-3, in which
case such registration shall be on another appropriate form in accordance
herewith) and shall contain (except if otherwise required by the Commission) the
"PLAN OF DISTRIBUTION" attached hereto as ANNEX A. The Company shall use its
best efforts to cause each Registration Statement to be declared effective under
the Securities Act as promptly as possible, but in any event prior to the
applicable Effectiveness Date, and shall use its best efforts to keep such
Registration Statement continuously effective under the Securities Act until the
date which is two years after the date that such Registration Statement is
declared effective by the Commission or such earlier date when all Registrable
Securities covered by a Registration Statement have been sold or may be sold
without volume restrictions pursuant to Rule 144(k) as determined by the counsel
to the Company pursuant to a written opinion letter to such effect, addressed
and acceptable to the Company's transfer agent and the affected Holders (the
"EFFECTIVENESS PERIOD").

                  (b) If: (i) a Registration Statement is not filed on or prior
to its Filing Date (if the Company files a Registration Statement without
affording the Holder the opportunity to review and comment on the same as
required by Section 3(a), the Company shall not be deemed to have satisfied
clause (i)), or (ii) the Company fails to file with the Commission a request for
acceleration in accordance with Rule 461 promulgated under the Securities Act,
within five Trading Days of the date that the Company is notified (orally or in
writing, whichever is earlier) by the Commission that a Registration Statement

                                      -3-
<PAGE>

will not be "reviewed," or not subject to further review, or (iii) prior to its
Effective Date, the Company fails to file a pre-effective amendment and
otherwise respond in writing to comments made by the Commission in respect of
such Registration Statement within fifteen Trading Days after the receipt of
comments by or notice from the Commission that such amendment is required in
order for a Registration Statement to be declared effective, or (iv) a
Registration Statement filed or required to be filed hereunder is not declared
effective by the Commission by its Effectiveness Date, or (v) after the
Effective Date, a Registration Statement ceases for any reason to remain
continuously effective as to all Registrable Securities for which it is required
to be effective, or the Holders are not permitted to utilize the Prospectus
therein to resell such Registrable Securities, for in any such cases an
aggregate of twenty Trading Days (which need not be consecutive Trading Days)
(any such failure or breach being referred to as an "EVENT," and for purposes of
clause (i) or (iv) the date on which such Event occurs, or for purposes of
clause (ii) the date on which such five Trading Day period is exceeded, or for
purposes of clauses (iii) the date which such fifteen Trading Day period is
exceeded, or for purposes of clause (v) the date on which such twenty Trading
Day period is exceeded being referred to as "EVENT DATE"), then in addition to
any other rights the Holders may have under any Transaction Document (including
any right to require the payment in full of the Mandatory Prepayment Amount
under the Debentures), or applicable law (it being agreed that these damages are
not to be construed as the sole remedy for any Event but are in addition to any
other damages and remedies which may be or become due under the Transaction
Documents): (x) on each such Event Date the Company shall pay to each Holder an
amount in cash, as liquidated damages and not as a penalty, equal to 1.5% of the
aggregate investment amount paid by such Holder pursuant to the Purchase
Agreement; and (y) on each monthly anniversary of each such Event Date (if the
applicable Event shall not have been cured by such date) until the applicable
Event is cured, the Company shall pay to each Holder an amount in cash, as
liquidated damages and not as a penalty, equal to 1.5% of the aggregate
investment amount paid by such Holder pursuant to the Purchase Agreement. If the
Company fails to pay any liquidated damages pursuant to this Section in full
within seven days after the date payable, the Company will pay interest thereon
at a rate of 12% per annum (or such lesser maximum amount that is permitted to
be paid by applicable law) to the Holder, accruing daily from the date such
liquidated damages are due until such amounts, plus all such interest thereon,
are paid in full. Each Holder agrees that it will provide the Company with any
comments such Holder may have to a Registration Statement within five Trading
Days after such Holder's receipt of such Registration Statement. The Company
shall not be liable to pay any liquidated damages to a Holder due to a delay in
the Effectiveness Date if such delay is a result of such Holder's failure to
provide the Company with such Holders' comments to a Registration Statement.
Notwithstanding the foregoing, the amount of liquidated damages with respect to
a Registration Statement covering the Warrant Shares with respect to the
Adjustment Warrant (if such Warrant Shares are not included in the first
Registration Statement filed following the date hereof) shall be based on 1.5%
times the lesser of (i) the aggregate investment amount paid by such Holder
pursuant to the Purchase Agreement and (ii) the product of the Closing Price on
the Trading Day immediately prior to the Event Date at issue multiplied by the
number of Warrant Shares at issue.

                  (c) If the number of Registrable Securities issuable at any
time exceeds 85% of the number of shares of Common Stock then registered in a
Registration Statement, then the Company shall file an additional Registration
Statement covering the resale of by the Holders of not less than 125% of the

                                      -4-
<PAGE>

number of Registrable Securities required in order that all Underlying Shares
and all Warrant Shares issuable upon exercise of the Warrants would then be
registered in accordance with this Agreement.

                  (d) Notwithstanding anything herein to the contrary, the
Company shall prepare and file a Registration Statement covering the resale of
shares of Common Stock issuable upon exercise of each Adjustment Warrant within
30 days following each issuance of such Adjustable Warrant.

         3. REGISTRATION PROCEDURES

                  In connection with the Company's registration obligations
hereunder, the Company shall:

                  (a) Not less than five Trading Days prior to the filing of the
Registration Statement or any related Prospectus or any amendment or supplement
thereto, the Company shall, (i) furnish to the Holders and their Special Counsel
copies of all such documents proposed to be filed (including documents
incorporated or deemed incorporated by reference) which documents will be
subject to the review of such Holders and their Special Counsel, and (ii) cause
its officers and directors, counsel and independent certified public accountants
to respond to such inquiries as shall be necessary, in the reasonable opinion of
respective counsel to conduct a reasonable investigation within the meaning of
the Securities Act. The Company shall not file the Registration Statement or any
such Prospectus or any amendments or supplements thereto to which the Holders of
a majority of the Registrable Securities and their Special Counsel shall
reasonably object in good faith.

                  (b) (i) Prepare and file with the Commission such amendments,
including post-effective amendments, to the Registration Statement and the
Prospectus used in connection therewith as may be necessary to keep the
Registration Statement continuously effective as to the applicable Registrable
Securities for the Effectiveness Period and prepare and file with the Commission
such additional Registration Statements in order to register for resale under
the Securities Act all of the Registrable Securities; (ii) cause the related
Prospectus to be amended or supplemented by any required Prospectus supplement,
and as so supplemented or amended to be filed pursuant to Rule 424; (iii)
respond as promptly as reasonably possible, and in any event within fifteen
Trading Days, to any comments received from the Commission with respect to the
Registration Statement or any amendment thereto and, as promptly as reasonably
possible provide the Holders true and complete copies of all correspondence from
and to the Commission relating to the Registration Statement; and (iv) comply in
all material respects with the provisions of the Securities Act and the Exchange
Act with respect to the disposition of all Registrable Securities covered by the
Registration Statement during the applicable period in accordance with the
intended methods of disposition by the Holders thereof set forth in the
Registration Statement as so amended or in such Prospectus as so supplemented.

                  (c) Notify the Holders of Registrable Securities to be sold
and their Special Counsel as promptly as reasonably possible (and, in the case
of (i)(A) below, not less than three Trading Days prior to such filing) and (if
requested by any such Person) confirm such notice in writing no later than one
Trading Day following the day (i)(A) when a Prospectus or any Prospectus

                                      -5-
<PAGE>

supplement or post-effective amendment to the Registration Statement is proposed
to be filed; (B) when the Commission notifies the Company whether there will be
a "review" of such Registration Statement and whenever the Commission comments
in writing on such Registration Statement (the Company shall provide true and
complete copies thereof and all written responses thereto to each of the
Holders); and (C) with respect to the Registration Statement or any
post-effective amendment, when the same has become effective; (ii) of any
request by the Commission for amendments or supplements to the Registration
Statement or Prospectus or for additional information; (iii) of the issuance by
the Commission of any stop order suspending the effectiveness of the
Registration Statement covering any or all of the Registrable Securities or the
initiation of any Proceedings for that purpose; (iv) of the receipt by the
Company of any notification with respect to the suspension of the qualification
or exemption from qualification of any of the Registrable Securities for sale in
any jurisdiction, or the initiation or threatening of any Proceeding for such
purpose; and (v) of the occurrence of any event or passage of time that makes
the financial statements included in the Registration Statement ineligible for
inclusion therein or any statement made in the Registration Statement or
Prospectus or any document incorporated or deemed to be incorporated therein by
reference untrue in any material respect or that requires any revisions to the
Registration Statement, Prospectus or other documents so that, in the case of
the Registration Statement or the Prospectus, as the case may be, it will not
contain any untrue statement of a material fact or omit to state any material
fact required to be stated therein or necessary to make the statements therein,
in light of the circumstances under which they were made, not misleading.

                  (d) Use its best efforts to avoid the issuance of, or, if
issued, obtain the withdrawal of (i) any order suspending the effectiveness of
the Registration Statement, or (ii) any suspension of the qualification (or
exemption from qualification) of any of the Registrable Securities for sale in
any jurisdiction, at the earliest practicable moment.

                  (e) Furnish to each Holder and their Special Counsel, without
charge, at least one conformed copy of each Registration Statement and each
amendment thereto, including financial statements and schedules, all documents
incorporated or deemed to be incorporated therein by reference, and all exhibits
to the extent requested by such Person (including those previously furnished or
incorporated by reference) promptly after the filing of such documents with the
Commission; provided, however, if the Registration Statement is on Form S-3,
then the Company shall not be obligated to provide copies of any financial
statements incorporated by reference therein, but only to the extent that such
financial statements have been previously filed with the Commission.

                  (f) Promptly deliver to each Holder and their Special Counsel,
without charge, as many copies of the Prospectus or Prospectuses (including each
form of prospectus) and each amendment or supplement thereto as such Persons may
reasonably request. The Company hereby consents to the use of such Prospectus
and each amendment or supplement thereto by each of the selling Holders in
connection with the offering and sale of the Registrable Securities covered by
such Prospectus and any amendment or supplement thereto and each Holder agrees
to comply with the prospectus delivery requirements in accordance with the
Securities Act in connection with sales made by such Holder of the Registrable
Securities.

                                      -6-
<PAGE>

                  (g) Prior to any public offering of Registrable Securities,
use its best efforts to register or qualify or cooperate with the selling
Holders and their Special Counsel in connection with the registration or
qualification (or exemption from such registration or qualification) of such
Registrable Securities for offer and sale under the securities or Blue Sky laws
of such jurisdictions within the United States as any Holder requests in
writing, to keep each such registration or qualification (or exemption
therefrom) effective during the Effectiveness Period and to do any and all other
acts or things necessary or advisable to enable the disposition in such
jurisdictions of the Registrable Securities covered by a Registration Statement;
PROVIDED, that the Company shall not be required to qualify generally to do
business in any jurisdiction where it is not then so qualified or subject the
Company to any material tax in any such jurisdiction where it is not then so
subject.

                  (h) Cooperate with the Holders to facilitate the timely
preparation and delivery of certificates representing Registrable Securities to
be delivered to a transferee pursuant to a Registration Statement, which
certificates shall be free, to the extent permitted by the Purchase Agreement,
of all restrictive legends, and to enable such Registrable Securities to be in
such denominations and registered in such names as any such Holders may request.

                  (i) Upon the occurrence of any event contemplated by Section
3(c)(v), as promptly as reasonably possible, prepare a supplement or amendment,
including a post-effective amendment, to the Registration Statement or a
supplement to the related Prospectus or any document incorporated or deemed to
be incorporated therein by reference, and file any other required document so
that, as thereafter delivered, neither the Registration Statement nor such
Prospectus will contain an untrue statement of a material fact or omit to state
a material fact required to be stated therein or necessary to make the
statements therein, in light of the circumstances under which they were made,
not misleading.

                  (j) Comply with all applicable rules and regulations of the
Commission.

                  (k) The Company may require, at any time prior to the third
Trading Day prior to the Filing Date, each selling Holder to furnish to the
Company a certified statement as to the number of shares of Common Stock
beneficially owned by such Holder and, if requested by the Commission, the
controlling person thereof, within three Trading Days of the Company's request.

         4. REGISTRATION EXPENSES. All fees and expenses incident to the
performance of or compliance with this Agreement by the Company shall be borne
by the Company whether or not any Registrable Securities are sold pursuant to
the Registration Statement. The fees and expenses referred to in the foregoing
sentence shall include, without limitation, (i) all registration and filing fees
(including, without limitation, fees and expenses (A) with respect to filings
required to be made with the Trading Market on which the Common Stock is then
listed for trading, and (B) in compliance with applicable state securities or
Blue Sky laws), (ii) printing expenses (including, without limitation, expenses
of printing certificates for Registrable Securities and of printing prospectuses
if the printing of prospectuses is reasonably requested by the holders of a
majority of the Registrable Securities included in the Registration Statement),
(iii) messenger, telephone and delivery expenses, (iv) fees and disbursements of
counsel for the Company, (v) Securities Act liability insurance, if the Company

                                      -7-
<PAGE>

so desires such insurance, and (vi) fees and expenses of all other Persons
retained by the Company in connection with the consummation of the transactions
contemplated by this Agreement. In addition, the Company shall be responsible
for all of its internal expenses incurred in connection with the consummation of
the transactions contemplated by this Agreement (including, without limitation,
all salaries and expenses of its officers and employees performing legal or
accounting duties), the expense of any annual audit and the fees and expenses
incurred in connection with the listing of the Registrable Securities on any
securities exchange as required hereunder.

         5. INDEMNIFICATION

                  (a) INDEMNIFICATION BY THE COMPANY. The Company shall,
notwithstanding any termination of this Agreement, indemnify and hold harmless
each Holder, the officers, directors, agents, brokers (including brokers who
offer and sell Registrable Securities as principal as a result of a pledge or
any failure to perform under a margin call of Common Stock), investment advisors
and employees of each of them, each Person who controls any such Holder (within
the meaning of Section 15 of the Securities Act or Section 20 of the Exchange
Act) and the officers, directors, agents and employees of each such controlling
Person, to the fullest extent permitted by applicable law, from and against any
and all losses, claims, damages, liabilities, costs (including, without
limitation, reasonable costs of preparation and reasonable attorneys' fees) and
expenses (collectively, "Losses"), as incurred, arising out of or relating to
any untrue or alleged untrue statement of a material fact contained in the
Registration Statement, any Prospectus or any form of prospectus or in any
amendment or supplement thereto or in any preliminary prospectus, or arising out
of or relating to any omission or alleged omission of a material fact required
to be stated therein or necessary to make the statements therein (in the case of
any Prospectus or form of prospectus or supplement thereto, in light of the
circumstances under which they were made) not misleading, except to the extent,
but only to the extent, that (1) such untrue statements or omissions are based
solely upon information regarding such Holder furnished in writing to the
Company by such Holder expressly for use therein, or to the extent that such
information relates to such Holder or such Holder's proposed method of
distribution of Registrable Securities and was reviewed and expressly approved
in writing by such Holder expressly for use in the Registration Statement, such
Prospectus or such form of Prospectus or in any amendment or supplement thereto
(it being understood that the Holder has approved Annex A hereto for this
purpose) or (2) in the case of an occurrence of an event of the type specified
in Section 3(c)(ii)-(v), the use by such Holder of an outdated or defective
Prospectus after the Company has notified such Holder in writing that the
Prospectus is outdated or defective and prior to the receipt by such Holder of
the Advice contemplated in Section 6(d). The Company shall notify the Holders
promptly of the institution, threat or assertion of any Proceeding of which the
Company is aware in connection with the transactions contemplated by this
Agreement.

                  (b) INDEMNIFICATION BY HOLDERS. Each Holder shall, severally
and not jointly, indemnify and hold harmless the Company, its directors,
officers, agents and employees, each Person who controls the Company (within the
meaning of Section 15 of the Securities Act and Section 20 of the Exchange Act),
and the directors, officers, agents or employees of such controlling Persons, to
the fullest extent permitted by applicable law, from and against all Losses, as
incurred, arising solely out of or based solely upon: (x) such Holder's failure
to comply with the prospectus delivery requirements of the Securities Act or (y)
any untrue statement of a material fact contained in any Registration Statement,

                                      -8-
<PAGE>

any Prospectus, or any form of prospectus, or in any amendment or supplement
thereto, or arising solely out of or based solely upon any omission of a
material fact required to be stated therein or necessary to make the statements
therein not misleading to the extent, but only to the extent, that such untrue
statement or omission is contained in any information so furnished in writing by
such Holder to the Company specifically for inclusion in such Registration
Statement or such Prospectus or to the extent that (1) such untrue statements or
omissions are based solely upon information regarding such Holder furnished in
writing to the Company by such Holder expressly for use therein, or to the
extent that such information relates to such Holder or such Holder's proposed
method of distribution of Registrable Securities and was reviewed and expressly
approved in writing by such Holder expressly for use in the Registration
Statement (it being understood that the Holder has approved Annex A hereto for
this purpose), such Prospectus or such form of Prospectus or in any amendment or
supplement thereto or (2) in the case of an occurrence of an event of the type
specified in Section 3(c)(ii)-(v), the use by such Holder of an outdated or
defective Prospectus after the Company has notified such Holder in writing that
the Prospectus is outdated or defective and prior to the receipt by such Holder
of the Advice contemplated in Section 6(d). In no event shall the liability of
any selling Holder hereunder be greater in amount than the dollar amount of the
net proceeds received by such Holder upon the sale of the Registrable Securities
giving rise to such indemnification obligation.

                  (c) CONDUCT OF INDEMNIFICATION PROCEEDINGS. If any Proceeding
shall be brought or asserted against any Person entitled to indemnity hereunder
(an "INDEMNIFIED PARTY"), such Indemnified Party shall promptly notify the
Person from whom indemnity is sought (the "INDEMNIFYING PARTY") in writing, and
the Indemnifying Party shall assume the defense thereof, including the
employment of counsel reasonably satisfactory to the Indemnified Party and the
payment of all fees and expenses incurred in connection with defense thereof;
provided, that the failure of any Indemnified Party to give such notice shall
not relieve the Indemnifying Party of its obligations or liabilities pursuant to
this Agreement, except (and only) to the extent that it shall be finally
determined by a court of competent jurisdiction (which determination is not
subject to appeal or further review) that such failure shall have proximately
and materially adversely prejudiced the Indemnifying Party.

                  An Indemnified Party shall have the right to employ separate
counsel in any such Proceeding and to participate in the defense thereof, but
the fees and expenses of such counsel shall be at the expense of such
Indemnified Party or Parties unless: (1) the Indemnifying Party has agreed in
writing to pay such fees and expenses; (2) the Indemnifying Party shall have
failed promptly to assume the defense of such Proceeding and to employ counsel
reasonably satisfactory to such Indemnified Party in any such Proceeding; or (3)
the named parties to any such Proceeding (including any impleaded parties)
include both such Indemnified Party and the Indemnifying Party, and such
Indemnified Party shall have been advised by counsel that a conflict of interest
is likely to exist if the same counsel were to represent such Indemnified Party
and the Indemnifying Party (in which case, if such Indemnified Party notifies
the Indemnifying Party in writing that it elects to employ separate counsel at
the expense of the Indemnifying Party, the Indemnifying Party shall not have the
right to assume the defense thereof on behalf of the Indemnified Party and such
additional counsel shall be at the expense of the Indemnifying Party). The

                                      -9-
<PAGE>

Indemnifying Party shall not be liable for any settlement of any such Proceeding
effected without its written consent, which consent shall not be unreasonably
withheld. No Indemnifying Party shall, without the prior written consent of the
Indemnified Party, effect any settlement of any pending Proceeding in respect of
which any Indemnified Party is a party, unless such settlement includes an
unconditional release of such Indemnified Party from all liability on claims
that are the subject matter of such Proceeding.

                  All fees and expenses of the Indemnified Party (including
reasonable fees and expenses to the extent incurred in connection with
investigating or preparing to defend such Proceeding in a manner not
inconsistent with this Section) shall be paid to the Indemnified Party, as
incurred, within ten Trading Days of written notice thereof to the Indemnifying
Party (regardless of whether it is ultimately determined that an Indemnified
Party is not entitled to indemnification hereunder; PROVIDED, that the
Indemnifying Party may require such Indemnified Party to undertake to reimburse
all such fees and expenses to the extent it is finally judicially determined
that such Indemnified Party is not entitled to indemnification hereunder).

                  (d) CONTRIBUTION. If a claim for indemnification under Section
5(a) or 5(b) is unavailable to an Indemnified Party (by reason of public policy
or otherwise), then each Indemnifying Party, in lieu of indemnifying such
Indemnified Party, shall contribute to the amount paid or payable by such
Indemnified Party as a result of such Losses, in such proportion as is
appropriate to reflect the relative fault of the Indemnifying Party and
Indemnified Party in connection with the actions, statements or omissions that
resulted in such Losses as well as any other relevant equitable considerations.
The relative fault of such Indemnifying Party and Indemnified Party shall be
determined by reference to, among other things, whether any action in question,
including any untrue or alleged untrue statement of a material fact or omission
or alleged omission of a material fact, has been taken or made by, or relates to
information supplied by, such Indemnifying Party or Indemnified Party, and the
parties' relative intent, knowledge, access to information and opportunity to
correct or prevent such action, statement or omission. The amount paid or
payable by a party as a result of any Losses shall be deemed to include, subject
to the limitations set forth in Section 5(c), any reasonable attorneys' or other
reasonable fees or expenses incurred by such party in connection with any
Proceeding to the extent such party would have been indemnified for such fees or
expenses if the indemnification provided for in this Section was available to
such party in accordance with its terms.

                  The parties hereto agree that it would not be just and
equitable if contribution pursuant to this Section 5(d) were determined by pro
rata allocation or by any other method of allocation that does not take into
account the equitable considerations referred to in the immediately preceding
paragraph. Notwithstanding the provisions of this Section 5(d), no Holder shall
be required to contribute, in the aggregate, any amount in excess of the amount
by which the proceeds actually received by such Holder from the sale of the
Registrable Securities subject to the Proceeding exceeds the amount of any
damages that such Holder has otherwise been required to pay by reason of such
untrue or alleged untrue statement or omission or alleged omission.

                  The indemnity and contribution agreements contained in this
Section are in addition to any liability that the Indemnifying Parties may have
to the Indemnified Parties.

                                      -10-
<PAGE>

         6. MISCELLANEOUS

                  (a) REMEDIES. In the event of a breach by the Company or by a
Holder, of any of their obligations under this Agreement, each Holder or the
Company, as the case may be, in addition to being entitled to exercise all
rights granted by law and under this Agreement, including recovery of damages,
will be entitled to specific performance of its rights under this Agreement. The
Company and each Holder agree that monetary damages would not provide adequate
compensation for any losses incurred by reason of a breach by it of any of the
provisions of this Agreement and hereby further agree that, in the event of any
action for specific performance in respect of such breach, it shall waive the
defense that a remedy at law would be adequate.

                  (b) OTHER REGISTRATIONS. Prior to the third month anniversary
of the Effective Date, the Company shall not, directly or indirectly, file any
other registration statement with the Commission with respect to any securities
of the Company, except for a Form S-8 or a prospectus supplement or amendment to
any current effective registration statement; provided that no such registration
statement shall have the effect of registering additional shares of Common Stock
originally covered by such registration statement or realizing a lower price per
share than as initially disclosed in such registration statement. Except as and
to the extent specified in SCHEDULE 6(B) hereto or as otherwise contemplated by
the Transaction Documents or for the registration rights granted pursuant to the
ZLP Purchase Agreement (and the transactions contemplated thereby), neither the
Company nor any of its security holders (other than the Holders in such capacity
pursuant hereto) may include securities of the Company in the Registration
Statement other than the Registrable Securities, and the Company shall not after
the date hereof enter into any agreement providing any such right to any of its
security holders. Except as and to the extent specified in this Agreement or in
SCHEDULE 6(B) hereto, the Company has not previously entered into any agreement
granting any registration rights with respect to any of its securities to any
Person which have not been fully satisfied.

                  (c) COMPLIANCE. Each Holder covenants and agrees that it will
comply with the prospectus delivery requirements of the Securities Act as
applicable to it in connection with sales of Registrable Securities pursuant to
the Registration Statement.

                  (d) DISCONTINUED DISPOSITION. Each Holder agrees by its
acquisition of such Registrable Securities that, upon receipt of a notice from
the Company of the occurrence of any event of the kind described in Section
3(c), such Holder will forthwith discontinue disposition of such Registrable
Securities under the Registration Statement until such Holder's receipt of the
copies of the supplemented Prospectus and/or amended Registration Statement or
until it is advised in writing (the "ADVICE") by the Company that the use of the
applicable Prospectus may be resumed, and, in either case, has received copies
of any additional or supplemental filings that are incorporated or deemed to be
incorporated by reference in such Prospectus or Registration Statement. The
Company may provide appropriate stop orders to enforce the provisions of this
paragraph.

                  (e) PIGGY-BACK REGISTRATIONS. If at any time during the
Effectiveness Period there is not an effective Registration Statement covering
all of the Registrable Securities and the Company shall determine to prepare and
file with the Commission a registration statement relating to an offering for

                                      -11-
<PAGE>

its own account or the account of others under the Securities Act of any of its
equity securities, other than on Form S-4 or Form S-8 (each as promulgated under
the Securities Act) or their then equivalents relating to equity securities to
be issued solely in connection with any acquisition of any entity or business or
equity securities issuable in connection with stock option or other employee
benefit plans, then the Company shall send to each Holder written notice of such
determination and, if within fifteen days after receipt of such notice, any such
Holder shall so request in writing, the Company shall include in such
registration statement all or any part of such Registrable Securities such
holder requests to be registered, subject to customary underwriter cutbacks
applicable to all holders of registration rights.

                  (f) AMENDMENTS AND WAIVERS. The provisions of this Agreement,
including the provisions of this sentence, may not be amended, modified or
supplemented, and waivers or consents to departures from the provisions hereof
may not be given, unless the same shall be in writing and signed by the Company
and the Holders of at least two-thirds of the then outstanding Registrable
Securities.

                  (g) NOTICES. Any and all notices or other communications or
deliveries required or permitted to be provided hereunder shall be in writing
and shall be deemed given and effective on the earliest of (i) the date of
transmission, if such notice or communication is delivered via facsimile at the
facsimile telephone number specified in this Section prior to 6:30 p.m. (New
York City time) on a Trading Day, (ii) the Trading Day after the date of
transmission, if such notice or communication is delivered via facsimile at the
facsimile telephone number specified in this Agreement later than 6:30 p.m. (New
York City time) on any date and earlier than 11:59 p.m. (New York City time) on
such date, (iii) the Trading Day following the date of mailing, if sent for next
day delivery by nationally recognized overnight courier service, or (iv) upon
actual receipt by the party to whom such notice is required to be given. The
address for such notices and communications shall be as follows:

         If to the Company:    Peregrine Pharmaceuticals, Inc.
                               14272 Franklin Avenue
                               Tustin, California 92780
                               Facsimile No.: (714) 838-5817
                               Attn: Chief Financial Officer

         With a copy to:       Jeffers, Shaff & Falk, LLP
                               18881 Von Karman Avenue, Suite 1400
                               Irvine, CA 92612
                               Facsimile No.: (949) 660-7799
                               Attn: Mark R. Ziebell, Esq.

         If to a Purchaser:    To the address set forth under such Purchaser's
                               name on the signature pages hereto.

                                      -12-
<PAGE>

         If to any other Person who is then the registered Holder:

                               To the address of such Holder as it appears in
                               the stock transfer books of the Company

or such other address as may be designated in writing hereafter, in the same
manner, by such Person.

                  (h) SUCCESSORS AND ASSIGNS. This Agreement shall inure to the
benefit of and be binding upon the successors and permitted assigns of each of
the parties and shall inure to the benefit of each Holder. The Company may not
assign its rights or obligations hereunder without the prior written consent of
each Holder. Each Holder may assign its rights hereunder in the manner and to
the Persons as permitted under the Purchase Agreement.

                  (i) EXECUTION AND COUNTERPARTS. This Agreement may be executed
in any number of counterparts, each of which when so executed shall be deemed to
be an original and, all of which taken together shall constitute one and the
same Agreement. In the event that any signature is delivered by facsimile
transmission, such signature shall create a valid binding obligation of the
party executing (or on whose behalf such signature is executed) the same with
the same force and effect as if such facsimile signature were the original
thereof.

                  (j) GOVERNING LAW. All questions concerning the construction,
validity, enforcement and interpretation of this Agreement shall be governed by
and construed and enforced in accordance with the internal laws of the State of
New York, without regard to the principles of conflicts of law thereof. Each
party agrees that all Proceedings concerning the interpretations, enforcement
and defense of the transactions contemplated by this Agreement and any other
Transaction Documents (whether brought against a party hereto or its respective
affiliates, directors, officers, stockholders, employees or agents) shall be
commenced exclusively in the state and federal courts sitting in the City of New
York, Borough of Manhattan. Each party hereto hereby irrevocably submits to the
exclusive jurisdiction of the state and federal courts sitting in the City of
New York, Borough of Manhattan for the adjudication of any dispute hereunder or
in connection herewith or with any transaction contemplated hereby or discussed
herein (including with respect to the enforcement of the any of the Transaction
Documents), and hereby irrevocably waives, and agrees not to assert in any
Proceeding, any claim that it is not personally subject to the jurisdiction of
any such court or that such Proceeding is improper. Each party hereto hereby
irrevocably waives personal service of process and consents to process being
served in any such Proceeding by mailing a copy thereof via registered or
certified mail or overnight delivery (with evidence of delivery) to such party
at the address in effect for notices to it under this Agreement and agrees that
such service shall constitute good and sufficient service of process and notice
thereof. Nothing contained herein shall be deemed to limit in any way any right
to serve process in any manner permitted by law. Each party hereto hereby
irrevocably waives, to the fullest extent permitted by applicable law, any and
all right to trial by jury in any legal proceeding arising out of or relating to
this Agreement or the transactions contemplated hereby. If either party shall
commence a Proceeding to enforce any provisions of a Transaction Document, then
the prevailing party in such Proceeding shall be reimbursed by the other party
for its attorney's fees and other costs and expenses incurred with the
investigation, preparation and prosecution of such Proceeding.

                                      -13-
<PAGE>

                  (k) CUMULATIVE REMEDIES. The remedies provided herein are
cumulative and not exclusive of any remedies provided by law.

                  (l) SEVERABILITY. If any term, provision, covenant or
restriction of this Agreement is held by a court of competent jurisdiction to be
invalid, illegal, void or unenforceable, the remainder of the terms, provisions,
covenants and restrictions set forth herein shall remain in full force and
effect and shall in no way be affected, impaired or invalidated, and the parties
hereto shall use their reasonable efforts to find and employ an alternative
means to achieve the same or substantially the same result as that contemplated
by such term, provision, covenant or restriction. It is hereby stipulated and
declared to be the intention of the parties that they would have executed the
remaining terms, provisions, covenants and restrictions without including any of
such that may be hereafter declared invalid, illegal, void or unenforceable.

                  (m) HEADINGS. The headings in this Agreement are for
convenience of reference only and shall not limit or otherwise affect the
meaning hereof.

                  (n) INDEPENDENT NATURE OF PURCHASERS' OBLIGATIONS AND RIGHTS.
The obligation of each Purchaser hereunder is several and not joint with the
obligations of any other Purchaser hereunder, and no Purchaser shall be
responsible in any way for the performance of the obligations of any other
Purchaser hereunder. Nothing contained herein or in any other agreement or
document delivered at any closing, and no action taken by any Purchaser pursuant
hereto or thereto, shall be deemed to constitute the Purchasers as a
partnership, an association, a joint venture or any other kind of entity, or
create a presumption that the Purchasers are in any way acting in concert with
respect to such obligations or the transactions contemplated by this Agreement.
Each Purchaser shall be entitled to protect and enforce its rights, including
without limitation the rights arising out of this Agreement, and it shall not be
necessary for any other Purchaser to be joined as an additional party in any
proceeding for such purpose.

                   [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK
                           SIGNATURE PAGES TO FOLLOW]

                                      -14-
<PAGE>

                  IN WITNESS WHEREOF, the parties have executed this
Registration Rights Agreement as of the date first written above.

                                         PEREGRINE PHARMACEUTICALS, INC

                                         By:
                                             -----------------------------------
                                         Name:
                                         Title:

                   [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK
                     SIGNATURE PAGES OF PURCHASER TO FOLLOW]

                                      -15-
<PAGE>

                  IN WITNESS WHEREOF, the parties have executed this
Registration Rights Agreement as of the date first written above.

                          By:
                             -----------------------------------------
                             Name:
                             Title:

                          Address for Notice:

                          with a copy to:
                                Bryan Cave LLP
                                1290 Avenue of the Americas
                                New York, NY  10104
                                Facsimile No.: (212) 541-4630 and (212) 541-1432
                                Attn: Eric L. Cohen, Esq.

                                      -16-
<PAGE>

                                     ANNEX A

                              PLAN OF DISTRIBUTION
                              --------------------

         The Selling Stockholders and any of their pledgees, assignees and
successors-in-interest may, from time to time, sell any or all of their shares
of Common Stock on any stock exchange, market or trading facility on which the
shares are traded or in private transactions. These sales may be at fixed or
negotiated prices. The Selling Stockholders may use any one or more of the
following methods when selling shares:

o        ordinary brokerage transactions and transactions in which the
         broker-dealer solicits purchasers;

o        block trades in which the broker-dealer will attempt to sell the shares
         as agent but may position and resell a portion of the block as
         principal to facilitate the transaction;

o        purchases by a broker-dealer as principal and resale by the
         broker-dealer for its account;

o        an exchange distribution in accordance with the rules of the applicable
         exchange;

o        privately negotiated transactions;

o        short sales

o        broker-dealers may agree with the Selling Stockholders to sell a
         specified number of such shares at a stipulated price per share;

o        a combination of any such methods of sale; and

o        any other method permitted pursuant to applicable law.

         The Selling Stockholders may also sell shares under Rule 144 under the
Securities Act, if available, rather than under this prospectus.

         Broker-dealers engaged by the Selling Stockholders may arrange for
other brokers-dealers to participate in sales. Broker-dealers may receive
commissions or discounts from the Selling Stockholders (or, if any broker-dealer
acts as agent for the purchaser of shares, from the purchaser) in amounts to be
negotiated. The Selling Stockholders do not expect these commissions and
discounts to exceed what is customary in the types of transactions involved.

         The Selling Stockholders may from time to time pledge or grant a
security interest in some or all of the shares of Common Stock, Debentures or
Warrants owned by them and, if they default in the performance of their secured
obligations, the pledgees or secured parties may offer and sell the shares of
Common Stock from time to time under this prospectus, or under an amendment to
this prospectus under Rule 424(b)(3) or other applicable provision of the
Securities Act of 1933 amending the list of Selling Stockholders to include the
pledgee, transferee or other successors in interest as Selling Stockholders
under this prospectus.

                                      -17-
<PAGE>

         The Selling Stockholders also may transfer the shares of Common Stock
in other circumstances, in which case the transferees, pledgees or other
successors in interest will be the selling beneficial owners for purposes of
this prospectus.

         The Selling Stockholders and any broker-dealers or agents that are
involved in selling the shares may be deemed to be "underwriters" within the
meaning of the Securities Act in connection with such sales. In such event, any
commissions received by such broker-dealers or agents and any profit on the
resale of the shares purchased by them may be deemed to be underwriting
commissions or discounts under the Securities Act. Each Selling Stockholder has
informed the Company that it does not have any agreement or understanding,
directly or indirectly, with any person to distribute the Common Stock.

         The selling shareholders may enter into hedging transactions with third
parties, which may in turn engage in short sales of the securities in the course
of hedging the position they assume. The selling shareholders may also enter
into short positions or other derivative transactions relating to the
securities, or interests in the securities, and deliver the securities, or
interests in the securities, to close out their short or other positions or
otherwise settle short sales or other transactions, or loan or pledge the
securities, or interests in the securities, to third parties that in turn may
dispose of these securities.

         The Company is required to pay all fees and expenses incident to the
registration of the shares. The Company has agreed to indemnify the Selling
Stockholders against certain losses, claims, damages and liabilities, including
liabilities under the Securities Act.

                                      -18-

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