Document:

EX-4.12

 Exhibit 4.12 

Group Irrevocable Guarantee for Maximum Amount 

Contract No.: 2013 Doc. No. 00131810064 
 To:
China Merchants Bank, Shenzhen Jinzhonghuan Sub-branch (the “Bank”) 
 According to the Guarantor and the Bank signed 2013 Doc.
No. 00131810064 “Group’s consolidated credit business cooperation agreement” (hereinafter “the Credit Business Cooperation Agreement”) on April 3, 2013, the guarantor agrees to issue an irrevocable letter of
guarantee to the Bank, to take the responsibility for all debt obligations from getting the credit from the Bank or the Bank’s branches by the affiliated companies (hereinafter “ borrower “) authorized by the guarantor, in accordance
with “credit business cooperation agreement”, specific guarantees below : 
 1. This Guarantee is unconditional and irrevocable for maximum
amount. The guarantee scope includes the credit principal (a maximum of not exceed the amount of credit line determined by the “credit business cooperation agreement”), the corresponding interest, penalty interest, liquidated damages, and
costs, obtained by the borrower from the Bank or the Bank’s branches, based on the “credit business cooperation agreement”, specific credit agreement, and credit business contracts. 

2. The guarantor confirm to bear the liability for all debt obligations from getting the credit from the Bank or the Bank’s branches by the borrower
during the credit period determined by the “credit agreement”, and guarantee to unconditionally settle all outstanding debt for the borrower at the date of receipt of the written notice from the Bank. 

Before the expiration of the credit period, if the Bank or the Bank’s branches in advance recourse to the borrower in accordance with “ credit
business cooperation agreement “ or each specific credit agreement , the provisions of business contracts , the guarantor still bear the joint responsibility in accordance with the contents of this Guarantee. 

If the actual used amount exceeds the allocated amount listed in the annex of the “credit business cooperation agreement” because of the line
adjustment stipulated by the “credit business cooperation agreement”, the guarantor confirm the excess amount included in the Article I of the this Guarantee, and the guarantor shall continue to bear the joint responsibility in accordance
with the contents of this Guarantee. 
 For the added new credit business authorized to subordinate enterprises according to the “credit business
cooperation agreement “, the guarantor has also confirmed to include it in the guarantee scope of this Guarantee, and the guarantor shall continue to bear the joint responsibility in accordance with the contents of this Guarantee. 

3. The term of the guarantee begins on the effective date of the guarantee and ends on the maturity date of each loan or other facilities or creditor’s
right for receivables of the Bank or two years after the date when each advance is made. The term of guarantee for renewal of each facility lasts for 2 years after expiry of the renewed period. 

 [ü] As the Bank and the Guarantor and / or the respective
borrower originally signed a credit business cooperation agreement / credit agreement, from the effective date of this Guarantee, the outstanding balance of the concrete business under the original agreement is included in the guarantee scope of
this Guarantee. (If the terms apply, call “ü” in [  ]). 
 4. The content of each loan,
trade finance or other credit business, between the borrower and the Bank’s respective branches according to the authorization of the guarantor under the “credit business cooperation agreement”, can be determined according to the
credit agreement or business contract between the borrower and the Bank’s respective braches. 
 5. If the Bank or the Bank’s branches provide
draft guarantee, issue letters of credit, letters of guarantee, the Guarantor shall bear joint and severable liability within the scope specified in this Guarantee for any advances of the Bank incurred by the above-said businesses after the expiry
of the Term of Facilities even if the Bank has not provided any advances for Borrower during the Term of Facilities. 
 Renewal of the Facility Agreement or
amendments of terms under it made between the Bank or the Bank’s branches and Borrower with regard to periods, interest rates and amounts of specific businesses during the performance of Facility Agreement, or the Bank’s branches’
adjustment of interest rates during Term of Facilities in accordance with the Facility Agreement and/or specific contracts are not subject to the Guarantor’s consent or acknowledgment, and have no impacts on the joint and severable liability
assumed by the Guarantor herein. 
 If the Bank or the Bank’s branches discover anything incompliant with its requirements in documents received for
providing letters of credits under the Facility Agreement, and Borrower admits the incompliance, the Guarantor shall assume liability for the principal and interest incurred by the external acceptance or payment, and shall not demur because the Bank
accepts the incompliance without obtaining the Guarantor’s consent or notifying the Guarantor. 
 Amendments to letters of credit and guarantee (or
stand-by letters of credit ), acceptance of time letters of credit or postponement of payment terms upon guarantee of due payment are not subject to the Guarantor’s consent or acknowledgement, and have no impacts on the joint and severable
liability assumed by the Guarantor herein. 
 6. The guarantor herein assumes the independent responsibility for the guarantee. The guarantee issued by the
third party to the borrower held by the Bank or the Bank’s branches, have no impacts on the joint and severable liability assumed by the Guarantor herein. The guarantor is still independently liable to pay off all secured debt obligations. 

7. The guarantor represent and warrant that: 
 7.1 the guarantor
is approved by                                 , the legal person with license of
the business corporation issued by the Industrial and Commercial Administrative Department, and has enough property to repay a corresponding amount of the guarantee, to ensure to fulfill obligations specified in the Guarantee herein. 

 7.2 the financial statements and other documents provided by the guarantor to the Bank are true and valid. 

7.3 The guarantor issued that the Guarantee by the guarantor is the true meaning of that. 

7.4 If any change to the Guarantor’s industry and commercial registration, organization structure, business operation or financial conditions, may impact
the Guarantor’s capability of performing the guarantee, the Guarantor shall immediately notify the Bank. 
 8. The guarantee is independent,
continuously effective, irrevocable and unconditional. It is unaffected by the effectiveness of the Facility Agreement and other specific contracts, or any agreements and documents between the Borrower and any organizations and person, or
fraudulence, reorganization, suspension of business, dismissal, liquidation, bankruptcy, merger, division and reform of the Borrower, or any extension and postpone of time for the Borrower by the Bank or delaying in exercising the right to demand
repayment from the Borrower. 
 Even if the Bank waives, change or release the pledge, mortgage or relieves other guarantors from liability, the Guarantor
shall assume the guarantee liability in accordance with the guarantee. 
 9. No matter whether the creditor’s rights of the maximum amount guarantee
are confirmed, when the Bank transfer its creditor’s rights under the Facility Agreement to a third party, the maximum amount guarantee will be transferred to the assignee of the creditor’s rights. 

After the creditor’s rights of the guarantee are confirmed, when the Bank transfers part of its creditor’s rights, the Guarantor’s accessory
rights under the guarantee will be partly transferred. The Bank and the assignee of the transferred creditor’s rights will jointly share the rights and interests of the Guarantor under the guarantee; before the creditor’s rights under the
guarantee are confirmed, if the Bank transfers part of its creditor’s rights, the rights and interests will be transferred partly. The maximum amount of the Bank’s main creditor’s rights under the previous maximum amount guarantee
will decrease (the maximum amount of the Bank’s main creditor’s rights less the transferred part of the creditor’s rights). After the main creditor’s rights of the remaining part are confirmed, the Bank and the assignee of the
transferred creditor’s rights will share the rights and interests of the Guarantor under the guarantee. 
 10. During the term of validity of the
Guarantee herein, the Bank and the Bank’ branches impose any grace for any borrower’s default or delay behavior or delay the implementation of “credit business cooperation agreement” and each specific credit agreements, business
contracts and the rights enjoyed by the Bank or the Bank’s branches under the Guarantee herein, which do not mean that the Bank or the Bank’s branches give up such rights. 

11. For any change of communication data listed in Guarantee herein, the Guarantor guarantee to notify the Bank within three days. Any notice issued by the
Bank to the Guarantor, by such as telex , telegraph, facsimile, then once sent out ; by letter, posted in five days ; If delivery by person, once delivered out or within the business premises of the Guarantor, are deemed to have been served on the
guarantor. 
 12. The Guarantor confirmed that: the Guarantee herein applies for the law of The People’s Republic of China. During the term of validity
of the Guarantee herein, for any dispute or issue, the guarantor agreed to settle it according to “credit business cooperation agreement” or the dispute settlement method stipulated by the specific credit agreements and business contracts
between the borrower and the Bank or the Bank’s branches. 

 13. This Guarantee will come into effect subject to signatures of the Authorized Signatory (or signature stamps)
and the official seals of the Guarantor. 
 14. The Guarantee is made in four copies, two for the Bank and the Guarantor respectively, with equal legal
force. 
 ------ 
 (This page is signature page) 

Special Note : 
 The guarantor has confirmed that the Bank
has required the guarantor to notice and understand terms about relief or restrict of the Bank’s responsibility, rights only enjoyed by the Bank, and increase of responsibilities of other parties or restrict of their rights. The Bank has
explained such clauses at the request of the guarantor. The guarantor has full and exact understanding about all clauses in the guarantee. The guarantor has consistent understandings with the Bank about the clause in the guarantee. 

Guarantor ( stamp ) : 
 Authorized Signatory ( signed ) :

 Guarantor Address: 
  

					
	 Phone:
	 	Fax :	 	Postal Code:

 Guarantor Bank: 
 Account: 

April 3, 2013EX-10.1

 Exhibit 10.1 
  

 
 March 9, 2014 

Eric Compton 
 Dear Eric, 

I am delighted to welcome you to Hologic. You are joining a company with a tradition of excellence in providing innovative solutions to the field of
women’s health. I am pleased to offer you the position of Chief Operating Officer reporting to Steve MacMillan, Chief Executive Officer. Please note that all offers are contingent based upon successful completion of references and a background
check. 
 Start Date 
 Your start date will be on
April 14, 2014. 
 Salary 
 Your biweekly base
salary for this position will be $17,307.69 (equivalent to $450,000 on an annualized basis). 
 Relocation 

You are eligible to submit relocation expenses for reimbursement up to $200,000. This value is pending the determination of issues relating to the sale of your
home. As such, the relocation reimbursement may exceed $200,000; Hologic will work with you to agree upon the final reimbursement amount with the understanding that any increase in the amount beyond $200,000 will be in Hologic’s sole
discretion. All relocation benefits will be grossed up for taxes. A formalized Relocation Assistance Plan is forthcoming. Additionally, you will be provided temporary housing at Hologic’s expense in advance of your relocation in the Marlborough
area. 
 Benefit Plans and Programs 
 You will be
eligible to participate in Hologic’s benefit programs. Please note that all insurance plans, benefits, as well as Company policies and procedures are subject to change without notice. You will have five (5) weeks of vacation time per year.
Details will be provided during your first week of employment. Each year you will be eligible for additional Long Term Incentive Awards commensurate with your role as Chief Operating Officer, as determined by the Board of Directors. 

Stock Options 
 As part of Hologic’s Long Term
Incentive Program, you will be granted an option to purchase shares of currently authorized Company stock which will be subject to the terms and conditions set forth in Hologic’s standard stock option agreement with the value of $350,000. The
stock option grant, which we believe will represent a valuable equity position in Hologic, will have a grant price based on Hologic’s closing price (listed on the NASDAQ) on your first day of employment (grant date). This option will vest at a
rate of 20% per year, the first 20% vesting one year from the grant date (100% vested five years from the grant date). A detailed stock option agreement will be provided to you following the start of your employment. 

  

 

 

 

 
  

 Restricted Stock Units 

As part of Hologic’s Long Term Incentive Program, you will be awarded a Restricted Stock Unit grant upon hire with the value of $350,000. This grant will
be subject to the terms and conditions set forth in Hologic’s standard RSU agreement. The RSU grant, which we believe will represent a valuable equity position in Hologic, will vest at a rate of 25% per year, the first vesting one year
from the award data (100% vested 4 years from your first day of employment). A detailed RSU agreement will be provided to you following the start of your employment. 

Performance Share Stock Units 
 As part of Hologic’s
Long Term Incentive Program, you will be awarded a Performance Share Unit grant upon hire with the value of $750,000. This grant will be subject to the terms and conditions set forth in Hologic’s standard PSU agreement. The PSU grant, which we
believe will represent a valuable equity position in Hologic, will vest 100% on the third anniversary of your employment date (grant date). A detailed PSU agreement will be provided to you following the start of your employment. 

Accelerated Sign-On Award 
 If your first day of
employment is on or before April 14, 2014, you will be awarded a one-time special bonus of $482,375.00 payable within 14 days of your first day of employment. This one-time award is to replace an award from your prior employer in order to
accelerate your joining Hologic. You understand and agree that if you voluntarily terminate employment or your employment is ended for Cause (as those terms are defined in your Severance and Change of Control Agreement), within twelve
(12) months from your hire date, you hereby agree to repay Hologic, within 30 days of termination, the one-time special bonus on a pro-rated share, beginning as of month one (1) and the obligation will be reduced each month, or portion
thereof that you worked for Hologic, by one/twelfth of the cost. If your employment is terminated at any time by Hologic without Cause, or by you for Good Reason, you will not have a repayment obligation under this paragraph. 

Short-Term Incentive Plan (STIP) 
 You are eligible to
participate in Hologic’s Short-Term Incentive Plan, with a target incentive opportunity in fiscal year 2014 of 75% of base salary. Plan funding is based on company financial performance, and payouts are based on a combination of company
financial achievement and individual achievement. A threshold level of corporate financial achievement is required for any payments to be made. The Short-term Incentive Plan is measured and paid at the conclusion of the fiscal year. Any payout for
the current fiscal year will be pro-rated to reflect your tenure in this position. Please note that all compensation plans and programs are subject to change or cancellation without notice, and any Short-term Incentive payment will be subject to the
terms and conditions of the Plan. 
 Deferred Compensation Plan (DCP) 

You will be eligible for participation in the company’s DCP. You will receive a summary of this benefit as well as online account set up instructions
directly from Fidelity shortly. You may enroll during the annual enrollment period in the late fall to defer from your regular base salary and/or annual bonus during the following calendar year. In the meantime, you should elect your desired
distribution option for any Employer Retention Contribution that you may be eligible to receive. This election should be made within 30 days of becoming eligible (hire/promotion date). 

  
 

 

 

 
  

 Proof of Right to Work 

In accordance with federal immigration law, you will be required to provide to the Company documentary evidence of your identity and eligibility for employment
in the United States. Such documentation must be provided to the Company within three (3) business days of your hire date. Hologic, Inc. utilizes E-Verify, an internet-based program operated by the Department of Homeland Security in partnership
with Social Security Administration to verify every employee’s eligibility to work. 
 At Will Employment 

Your relationship with Hologic will be one of employment at will; employment is not for any specific term and may be terminated by either you or Hologic at any
time, for any reason with or without prior notice. Additionally, the Company requires you to verify that your employment at Hologic does not and will not breach any agreements entered into by you prior to employment with the Company (i.e., you
have not entered into any agreements with previous employers that are in conflict with your obligations to the Company). Please provide us with a copy of any such agreements.

Non-Compete/Confidentiality/Proprietary Agreements 
 You
have disclosed to Hologic that you are bound by a formal non-competition, confidentiality and proprietary agreement with your previous employer, Johnson & Johnson. You have provided a copy of that document to Hologic prior to Hologic
extending this offer, and Hologic has determined to extend this offer to you based upon its own legal determination that nothing in your prior agreement with Johnson & Johnson would preclude you from working for Hologic as its Chief
Operating Officer. In the event your employment with the Hologic results in a claim (whether through arbitration or court) by Johnson & Johnson, or any parent, successor or affiliate (collectively “Johnson & Johnson”),
alleging that you have breached any covenant of your employment, non-competition, confidentiality and proprietary agreements between you and Johnson & Johnson that have been provided to Hologic for review, Hologic shall indemnify you and
hold you harmless for any expenses, judgments, penalties, fines and amounts paid in settlement actually and reasonably incurred, including all attorney’s fees. Hologic shall advance reasonable attorneys’ fees and costs incurred by you to
defend against such action. 
 Your employment with Hologic is contingent upon you signing the Employee Intellectual Property Rights and Non-Competition
Agreement, as well as the securing of satisfactory reference and background checks. 
 This offer is valid through March 12, 2014 and requires a
response on or before that date. 
 Confidentiality 

You agree to follow the Company’s policy that employees must not disclose, either directly or indirectly, any confidential information, including any of
the terms of this agreement to any person including other employees of the Company. You may however discuss such terms with members of your immediate family and any legal, tax or accounting specialists who provide you with services, and to your
current employer, to the extent required by any current agreements you have with Johnson & Johnson to do so upon your termination of employment. 

  
 

 

 

 
  

 Please confirm your acceptance of this offer and the terms and conditions as described herein by executing
the attached copy of this letter and the Employee Intellectual Property Rights and Non-Competition Agreement. 
 We believe that joining Hologic is truly an
ideal opportunity for you to move to the next step in your career. You will be in a position to significantly influence Hologic’s growth and success. We are confident you will find working at Hologic an exciting and worthwhile venture. 

Congratulations! 
  

							
	Sincerely,	 		 	Accepted:	 	 /s/ Eric Compton

		 		 		 	Eric Compton
				
	

	 		 		 	
	Holly Lynch	 		 	Date:	 	 March 9, 2014

	Senior Vice President, Human Resources

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