Document:

<PAGE>

                                                                  Exhibit 10.8.3

      THIS WARRANT AND THE SECURITIES ISSUABLE UPON THE EXERCISE HEREOF HAVE NOT
      BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933. THEY MAY NOT BE SOLD,
      OFFERED FOR SALE, PLEDGED, HYPOTHECATED, OR OTHERWISE TRANSFERRED EXCEPT
      PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT
      OF 1933, OR AN OPINION OF COUNSEL SATISFACTORY TO THE COMPANY THAT
      REGISTRATION IS NOT REQUIRED UNDER SUCH ACT OR PURSUANT TO RULE 144 UNDER
      SUCH ACT.

      THESE SECURITIES MAY NOT BE TRANSFERRED EXCEPT IN ACCORDANCE WITH THE
      PROVISIONS OF REGULATION S UNDER THE SECURITIES ACT OF 1933, AS AMENDED,
      PURSUANT TO REGISTRATION UNDER THE SECURITIES ACT, OR PURSUANT TO AN
      AVAILABLE EXEMPTION FROM REGISTRATION. HEDGING TRANSACTIONS INVOLVING
      THESE SECURITIES MAY NOT BE CONDUCTED UNLESS IN COMPLIANCE WITH THE
      SECURITIES ACT.

Date of Issuance                                                      Void after
August __, 2006                                                  August __, 2013

                               BIOVEX GROUP, INC.
                   WARRANT TO PURCHASE SHARES OF CAPITAL STOCK

            For the mutual promises and other consideration contemplated by the
Note and Warrant Purchase Agreement (the "Purchase Agreement") dated as of
August __, 2006, the receipt and sufficiency of which are hereby acknowledged,
this Warrant is issued to _____________________________________ or its assigns
(the "Holder") by BioVex Group, Inc., a Delaware corporation (the "Company").
Capitalized terms not defined herein shall have the meaning set forth in the
Purchase Agreement.

            1. PURCHASE OF SHARES.

                  (a) Number of Shares Issuable. Subject to the terms and
conditions set forth herein and set forth in the Purchase Agreement, the Holder
is entitled, upon surrender of this Warrant at the principal office of the
Company (or at such other place as the Company shall notify the Holder in
writing), to purchase from the Company up to the number of fully paid and
nonassessable Warrant Shares as described in the Purchase Agreement (as adjusted
pursuant to Section 6 hereof).

                  (b) Exercise Price. The purchase price for the Warrant Shares
issuable pursuant to this Section 1 shall be equal to the Exercise Price defined
in Section 1 of the Purchase Agreement. The Warrant Shares and the purchase
price of such Warrant Shares shall be subject to adjustment pursuant to Section
6 hereof. Such purchase price, as adjusted from time to time, is herein referred
to as the "Exercise Price."

            2. EXERCISE PERIOD. This Warrant shall be exercisable at the
earliest to occur of (i) the closing of the Initial Public Offering and (ii) the
Maturity Date, and shall expire on August __, 2013 (the "Exercise Period"). With
respect to the Initial Public Offering, the Company shall provide notice to the
Holder of such Initial Public Offering at least ten (10) days prior to the
consummation of such Initial Public Offering.

<PAGE>

            3. METHOD OF EXERCISE.

                  (a) While this Warrant remains outstanding and exercisable in
accordance with Section 2 above, the Holder may exercise, in whole or in part,
the purchase rights evidenced hereby. Such exercise shall be effected by:

                        (i) the surrender of the Warrant, together with a duly
executed copy of the Notice of Exercise attached hereto, to the Secretary of the
Company at its principal office (or at such other place as the Company shall
notify the Holder in writing); and

                        (ii) the payment to the Company of an amount equal to
the aggregate Exercise Price for the number of Warrant Shares being purchased.

                  (b) Each exercise of this Warrant shall be deemed to have been
effected immediately prior to the close of business on the day on which this
Warrant is surrendered to the Company as provided in Section 3(a) above. At such
time, the person or persons in whose name or names any certificates for the
Warrant Shares shall be issuable upon such exercise as provided in Section 3(c)
below shall be deemed to have become the holder or holders of record of the
Warrant Shares represented by such certificates.

                  (c) As soon as practicable after the exercise of this Warrant
in whole or in part, and in any event within twenty (20) days thereafter, the
Company at its expense will cause to be issued in the name of, and delivered to,
the Holder, or as such Holder (upon payment by such Holder of any applicable
transfer taxes) may direct:

                        (i) a certificate or certificates for the number of
Warrant Shares to which such Holder shall be entitled, and

                        (ii) in case such exercise is in part only, a new
warrant or warrants (dated the date hereof) of like tenor, calling in the
aggregate on the face or faces thereof for the number of Warrant Shares equal to
the number of such Warrant Shares called for on the face of this Warrant minus
the number of Warrant Shares purchased by the Holder upon all exercises made in
accordance with Section 3(a) above or Section 4 below.

            4. NET EXERCISE. In lieu of exercising this Warrant for cash, the
Holder may elect to receive shares equal to the value of this Warrant (or the
portion thereof being exercised) by surrender of this Warrant at the principal
office of the Company together with notice of such election (a "Net Exercise").
In the event of such a Net Exercise, the Company shall issue to such Holder a
number of Warrant Shares computed using the following formula:

                           Y (A - B)
                           ---------
                      X =      A

      Where

            X =    The number of Warrant Shares to be issued to the Holder.

                                       2
<PAGE>

            Y =   The number of Warrant Shares purchasable under this Warrant
                  or, if only a portion of the Warrant is being exercised, the
                  portion of the Warrant being cancelled (at the date of such
                  calculation).

            A =   The fair market value of one (1) Warrant Share (at the date
                  of such calculation).

            B =   The Exercise Price (as adjusted to the date of such
                  calculations).

            For purposes of this Section 4, the fair market value of a Warrant
Share shall mean the average of the closing price of the Warrant Shares quoted
in the over-the-counter market in which the Warrant Shares are traded or the
closing price quoted on any exchange or electronic securities market on which
the Warrant Shares are listed, whichever is applicable, as published in The Wall
Street Journal for the thirty (30) trading days prior to the date of
determination of fair market value (or such shorter period of time during which
such Warrant Shares were traded over-the-counter or on such exchange). In the
event that this Warrant is exercised pursuant to this Section 4 in connection
with the Company's Initial Public Offering of its Common Stock, the fair market
value per Warrant Share shall be the product of (i) the per share offering price
to the public of the Company's Initial Public Offering, and (ii) the number of
shares of Common Stock into which each Warrant Share is convertible at the time
of such exercise. If the Warrant Shares are not traded on the over-the-counter
market, an exchange or an electronic securities market, the fair market value
shall be the price per Warrant Share that the Company could obtain from a
willing buyer for Warrant Shares sold by the Company from authorized but
unissued Warrant Shares, as such prices shall be determined in good faith by the
Company's Board of Directors.

            5. COVENANTS OF THE COMPANY.

                  (a) Notices of Record Date. In the event of any taking by the
Company of a record of the holders of any class of securities for the purpose of
determining the holders thereof who are entitled to receive any dividend (other
than a cash dividend which is the same as cash dividends paid in previous
quarters or a stock dividend) or other distribution, the Company shall mail to
the Holder, at least ten (10) days prior to such record date, a notice
specifying the date on which any such record is to be taken for the purpose of
such dividend or distribution.

                  (b) Covenants as to Exercise Shares. The Company covenants and
agrees that all Warrant Shares that may be issued upon the exercise of the
rights represented by this Warrant will, upon issuance in accordance with the
terms hereof, be validly issued and outstanding, fully paid and nonassessable,
and free from all taxes, liens and charges with respect to the issuance thereof.
The Company further covenants and agrees that the Company will at all times
during the Exercise Period have authorized and reserved, free from preemptive
rights, a sufficient number of shares of its capital stock to provide for the
exercise of the rights represented by this Warrant. If at any time during the
Exercise Period the number of authorized but unissued shares of capital stock
shall not be sufficient to permit exercise of this Warrant, the Company will
take such corporate action as may, in the opinion of its counsel, be necessary
to

                                       3
<PAGE>

increase its authorized but unissued shares of capital stock to such number
of shares as shall be sufficient for such purposes.

                  (c) No Impairment. Except and to the extent waived or
consented to by the Holder or as otherwise permitted under the terms hereof, the
Company will not, by amendment of its Certificate of Incorporation or through
any reorganization, transfer of assets, consolidation, merger, dissolution,
issue or sale of securities or any other voluntary action, avoid or seek to
avoid the observance or performance of any of the terms to be observed or
performed hereunder by the Company, but will at all times in good faith assist
in the carrying out of all the provisions of this Warrant and in the taking of
all such action as may be necessary or appropriate in order to protect the
exercise rights of the Holder against impairment.

            6. ADJUSTMENT OF EXERCISE PRICE AND NUMBER OF WARRANT SHARES. The
number of Warrant Shares purchasable upon exercise of this Warrant and the
Exercise Price shall be subject to adjustment from time to time as follows:

                  (a) Subdivisions, Combinations and Other Issuances. If the
Company shall at any time after the issuance but prior to the expiration of this
Warrant subdivide its Common Stock or Series D Preferred Stock, as the case may
be, by split-up or otherwise, or combine such capital stock, or issue additional
shares of such capital stock as a dividend with respect to any shares of such
capital stock, the number of Warrant Shares issuable on the exercise of this
Warrant shall forthwith be proportionately increased in the case of a
subdivision or stock dividend, or proportionately decreased in the case of a
combination. Appropriate adjustments shall also be made to the Exercise Price
payable per share, but the aggregate Exercise Price payable for the total number
of Warrant Shares purchasable under this Warrant (as adjusted) shall remain the
same. Any adjustment under this Section 6(a) shall become effective at the close
of business on the date the subdivision or combination becomes effective, or as
of the record date of such dividend, or in the event that no record date is
fixed, upon the making of such dividend.

                  (b) Reclassification, Reorganization and Consolidation. In
case of any reclassification, capital reorganization or change in the capital
stock of the Company (other than as a result of a subdivision, combination or
stock dividend provided for in Section 6(a) above), then, as a condition of such
reclassification, reorganization or change, lawful provision shall be made, and
duly executed documents evidencing the same from the Company or its successor
shall be delivered to the Holder, so that the Holder shall have the right at any
time prior to the expiration of this Warrant to purchase, at a total price equal
to that payable upon the exercise of this Warrant, the kind and amount of shares
of stock and other securities or property receivable in connection with such
reclassification, reorganization or change by a holder of the same number and
type of securities as were purchasable as Warrant Shares by the Holder
immediately prior to such reclassification, reorganization or change. In any
such case appropriate provisions shall be made with respect to the rights and
interest of the Holder so that the provisions hereof shall thereafter be
applicable with respect to any shares of stock or other securities or property
deliverable upon exercise hereof, and appropriate adjustments shall be made to
the Exercise Price per Warrant Share payable hereunder, provided the aggregate
Exercise Price shall remain the same.

                                       4
<PAGE>

                  (c) Notice of Adjustment. When any adjustment is required to
be made in the number or kind of shares, or property, purchasable upon exercise
of the Warrant, or in the Exercise Price, the Company shall promptly notify the
Holder of such event and of the number of Warrant Shares or other securities or
property thereafter purchasable upon exercise of this Warrant.

            7. NO FRACTIONAL SHARES OR SCRIP. No fractional shares or scrip
representing fractional shares shall be issued upon the exercise of this
Warrant, but in lieu of such fractional shares the Company shall make a cash
payment therefor on the basis of the Exercise Price then in effect.

            8. NO STOCKHOLDER RIGHTS OR LIABILITIES. Prior to exercise of this
Warrant, the Holder shall not be entitled to any rights of a stockholder with
respect to the Warrant Shares, including (without limitation) the right to vote
such Warrant Shares, receive dividends or other distributions thereon, exercise
preemptive rights or be notified of stockholder meetings, and except as
otherwise provided in this Warrant or the Purchase Agreement, such Holder (in
such capacity) shall not be entitled to any stockholder notice or other
communication concerning the business or affairs of the Company. No provisions
hereof, in the absence of affirmative action by the Holder to purchase stock,
and no enumeration herein of the rights or privileges of the Holder shall give
rise to any liability of the Holder as a stockholder of the Company.

            9. TRANSFER OF WARRANT. Subject to compliance with applicable
federal and state securities laws and any other contractual restrictions between
the Company and the Holder contained in the Purchase Agreement, this Warrant and
all rights hereunder are transferable in whole or in part by the Holder to any
person or entity upon written notice to the Company. Within a reasonable time
after the Company's receipt of an executed Assignment Form in the form attached
hereto, the transfer shall be recorded on the books of the Company upon the
surrender of this Warrant, properly endorsed, to the Company at its principal
offices, and the payment to the Company of all transfer taxes and other
governmental charges imposed on such transfer. In the event of a partial
transfer, the Company shall issue to the new holders one or more appropriate new
warrants.

            10. GOVERNING LAW. This Warrant shall be governed by and construed
under the laws of the Commonwealth of Massachusetts as applied to agreements
among Massachusetts residents, made and to be performed entirely within the
Commonwealth of Massachusetts.

            11. SUCCESSORS AND ASSIGNS. The terms and provisions of this Warrant
and the Purchase Agreement shall inure to the benefit of, and be binding upon,
the Company and the holders hereof and their respective successors and assigns.

            12. TITLES AND SUBTITLES. The titles and subtitles used in this
Warrant are used for convenience only and are not to be considered in construing
or interpreting this Warrant.

            13. NOTICES. All notices and other communications given or made
pursuant hereto shall be in writing and shall be deemed effectively given: (i)
upon personal delivery to the party to be notified, (ii) when sent by confirmed
electronic mail or facsimile if sent during normal business hours of the
recipient, (iii) five (5) days after having been sent by registered or

                                       5
<PAGE>

certified mail, return receipt requested, postage prepaid, or (iv) one (1) day
after deposit with an internationally recognized overnight courier, specifying
next day delivery, with written verification of receipt. All communications
shall be sent to the respective parties at the following addresses (or at such
other addresses as shall be specified by notice given in accordance with this
Section 13):

            If to the Company:

            BioVex Group, Inc.
            34 Commerce Way
            Woburn, MA  01801
            Attention:  Chief Financial Officer

            If to Holders:

            At the addresses shown on the signature pages hereto.

            14. ASSUMPTION OF WARRANT. If at any time while this Warrant, or any
portion thereof, is outstanding and unexpired there shall be a Corporate
Transaction, then, as a part of such transaction, lawful provision shall be made
so that the Holder shall thereafter be entitled to receive upon exercise of this
Warrant, during the period specified herein and upon payment of the Exercise
Price then in effect, the number of shares of stock or other securities or
property of the successor corporation resulting from the Corporate Transaction
which a holder of the shares deliverable upon exercise of this Warrant would
have been entitled to receive in such Corporate Transaction if this Warrant had
been exercised immediately before such Corporate Transaction, all subject to
further adjustment as provided in this Section 14; and, in any such case,
appropriate adjustment (as determined by the Company's Board of Directors) shall
be made in the application of the provisions herein set forth with respect to
the rights and interests thereafter of the Holder to the end that the provisions
set forth herein (including provisions with respect to changes in and other
adjustments of the number of Warrant Shares the Holder is entitled to purchase)
shall thereafter be applicable, as nearly as possible, in relation to any
Warrant Shares or other securities or other property thereafter deliverable upon
the exercise of this Warrant. For purposes of this Warrant, a "Corporate
Transaction" shall mean any transaction defined as a "Deemed Liquidation Event"
in the Company's current Restated Certificate of Incorporation on file with the
Secretary of State of the State of Delaware (the "Restated Certificate").

            15. AMENDMENTS AND WAIVERS; RESOLUTIONS OF DISPUTE; NOTICE. The
amendment or waiver of any term of this Warrant, the resolution of any
controversy or claim arising out of or relating to this Warrant and the
provision of notice shall be conducted pursuant to the terms of the Purchase
Agreement.

                                       6
<PAGE>

            16. SEVERABILITY. If any provision of this Warrant is held to be
unenforceable under applicable law, such provision shall be excluded from this
Warrant and the balance of the Warrant shall be interpreted as if such provision
were so excluded and shall be enforceable in accordance with its terms.

                  [Remainder of Page Left Intentionally Blank.]

                                       7
<PAGE>

      IN WITNESS WHEREOF, the parties have executed this Agreement as of the
date above written,

                             BIOVEX GROUP, INC.

                             By: ______________________________________________
                                 Philip Astley-Sparke
                                 President and Chief Financial Officer

                             Address: 34 Commerce Way
                                      Woburn, MA  01801

ACKNOWLEDGED AND AGREED:

HOLDER

By: __________________________________

    __________________________________

    __________________________________

                                       8
<PAGE>

                               NOTICE OF EXERCISE

BioVex Group, Inc.
Attention:  Corporate Secretary

            The undersigned hereby elects to purchase, pursuant to the
provisions of the Warrant, as follows:

            ____  _____________ Warrant Shares pursuant to the terms of the
                  attached Warrant, and tenders herewith payment in cash of the
                  Exercise Price of such Warrant Shares in full, together with
                  all applicable transfer taxes, if any.

            ____  Net Exercise the attached Warrant with respect to __________
                  Warrant Shares.

            The undersigned hereby represents and warrants that Representations
and Warranties in Section 6 of the Purchase Agreement are true and correct as of
the date hereof.

                                        HOLDER:

Date:___________________                By:____________________________________

                                        Address: ______________________________

                                                 ______________________________

                                                 ______________________________

Name in which shares should be registered:

____________________________________________

<PAGE>

                                 ASSIGNMENT FORM

                    (To assign the foregoing Warrant, execute
                    this form and supply required information.
                    Do not use this form to purchase shares.)

      FOR VALUE RECEIVED, the foregoing Warrant and all rights evidenced thereby
are hereby assigned to

Name: _________________________________________________________________________
                                 (Please Print)

Address: ______________________________________________________________________
                                 (Please Print)

Dated: _________________

Holder's
Signature: _________________________________________

Holder's
Address:  __________________________________________

NOTE: The signature to this Assignment Form must correspond with the name as it
appears on the face of the Warrant. Officers of corporations and those acting in
a fiduciary or other representative capacity should provide proper evidence of
authority to assign the foregoing Warrant.<PAGE>

                                                                  Exhibit 10.9.1

                           SALE AND TRANSFER AGREEMENT

                                 BY AND BETWEEN

                                 BIOVEX LIMITED

                      (as seller and transferor and lessee)

                                       and

                   EUROPEAN VENTURE PARTNERS II ANNEX LIMITED

                   (as purchaser, transferee and head lessor)

                              Dated 25 / 08 / 2006

<PAGE>

AGREEMENT

BETWEEN

(1)  BIOVEX LIMITED incorporated in England with Registered Number 3480520 whose
     address is 70 Milton Park, Abingdon, Oxford OX14 4RX (the "lessee"); and

(2)  EUROPEAN VENTURE PARTNERS II ANNEX LIMITED, whose address is St Paul's
     Gate, New Street, St Helier, Jersey JE4 8ZB (the "Head lessor")

RECITALS

(A)  The lessee wishes to sell the Equipment (as defined in this agreement) to
     the Head lessor on the terms set out in this agreement.

(B)  The Head lessor wishes to purchase the Equipment from the lessee.

(C)  The Head lessor by separate agreement shall lease the Equipment to Venture
     Leasing (UK) Annex Limited (Company Number 05758881) (the "Head lessee")
     (the "Master Head-lease Agreement") and Head lessee shall by separate
     agreement entered into on the date hereof between the Head lessee and the
     lessee (the "Master Sub-lease Agreement") lease the Equipment back to the
     lessee.

IT IS AGREED as follows:

1.   Definitions

1.1  The expressions used herein are those used in the Master Sub-lease
     Agreement, unless expressly stated otherwise herein.

1.2  "Transfer Date" means the date hereof.

1.3  "Equipment" means the products described in ANNEX 1 attached hereto.

2.   SALE AND TRANSFER

2.1  The lessee hereby sells the Equipment with full title guarantee to the Head
     lessor with effect from the Transfer Date.

2.2  Physical delivery of the Equipment shall not take place but the parties
     hereby agree that the legal and beneficial ownership in the Equipment shall
     be transferred to the Head lessor with effect from the Transfer Date.

                                        2

<PAGE>

3.   RISK

     All risk of loss, theft and damage of and to the Equipment from any cause
     whatsoever remains with the lessee until such time as determined under the
     Master Sub-lease Agreement.

4.   PURCHASE PRICE

     In consideration for the sale and transfer of the Equipment, the Head
     lessor shall pay an aggregate purchase price of E3,000,000 plus value
     added tax at the prevailing rate of currently 17.5%

5.   REPRESENTATIONS AND WARRANTIES OF THE LESSEE

5.1. The lessee represents and warrants that the following statements are true
     and accurate as at the Transfer Date:

     a)   The lessee is the sole legal and beneficial owner of every item of the
          Equipment. The lessee can freely dispose of every item of the
          Equipment.

     b)   The Equipment is free of any lien, encumbrance and other rights
          created for the benefit of third parties.

     c)   The sale and transfer of the equipment and any part thereof does not
          require the consent of any other person or authority. The lessee is
          not restricted by any applicable law or any contract, agreement or
          arrangement to which it is a party to validly and effectively sell and
          transfer the equipment. There are no claims, options, rights of
          pre-emption or other agreements materially affecting the good and
          marketable title to the Equipment.

     d)   The Equipment is of satisfactory quality within the meaning of the
          Sale of Goods Act 1979, has, if and as applicable, been properly
          installed, operated and maintained in accordance the manufacturer's
          instructions whilst in the possession or ownership of the lessee and
          is in good working order.

     e)   The aggregate price to be paid by the Head lessor under clause 4
          reflects the fair replacement value of the Equipment at the date of
          this Agreement.

6.   MISCELLANEOUS

                                        3

<PAGE>

     This Sales Agreement is governed by and interpreted in accordance with
     English law and the parties hereto submit to the exclusive jurisdiction of
     the English Courts in relation to any matter arising herefrom.

Duly executed by the parties on the date set out on the front page

SIGNED BY
For and on behalf of
BIOVEX LIMITED

                                        /s/ P. Astley-Sparke
                                        ----------------------------------------
                                        Authorised Signatory

SIGNED BY
For and on behalf of
EUROPEAN VENTURE PARTNERS II
ANNEX LIMITED

                                        /s/ [ILLEGIBLE]
                                        ----------------------------------------
                                        Authorised Signatory

                                        4
<PAGE>

                                     ANNEX 1

ASSET
REGISTER

               BIOVEX                                             TOTAL SCHEDULE
COMPANY NAME   LIMITED        DRAWDOWN DATE           25-AUG-06   AMOUNT

LEASE

AGREEMENT NO         6        COMMENCEMENT DATE       01-OCT-06    E3,000,000.00
DRAWDOWN NO          1        TERMINATION DATE        30-SEP-09

<TABLE>
<CAPTION>
                   Asset     Date of
Asset Location   Category*   Invoice            Asset Description               Supplier        Invoice #
--------------   ---------   -------   -----------------------------------   -------------   ---------------
<S>              <C>         <C>       <C>                                   <C>             <C>
                                       Chessel 5100V with 6 channels
  Milton Park        3        Dec-05   & memory card                         Inlec           Y 36628
  Milton Park        3        Dec-05   Recorder, Monitor & filter            Amersham        Y 59146888
                                                                             Telephone
  Milton Park        3        Oct-05   Telephone system - cabling etc        Systems         Y TSS/I/121/05
                                       Chromotography Column                 Amersham
  Milton Park        3        Aug-05   (Bioreliance)                         Biosciences     Y 59132920
                                       Revco Ultima II Series upright                        Y
  Milton Park        3        Jul-05   Freezer                               Kendro          SLS/85001438
                                       Cryostorage Vessell, controller,
  Milton Park        3        Apr-05   vapour phase                          Jencons         Y 00342287
  Milton Park        3        Apr-05   Immunospot Series 3A Analyzer         CTL             Y 1-040705
                                                                             Web
  Milton Park        3        Mar-05   Bioneb Disruption System              Scientific      Y 89586
  Milton Park        3        Mar-05   Mini Prep Cell                        Bio-Rad         Y 320/25008595
  Milton Park        3        Oct-04   340L Fridge                           Jencons         Y 00332804
  Milton Park        3        Oct-04   Temperature monitoring system         Jencons         Y 00332804
                                       BPG140/500.100/750 4 way              Amersham
     Cobra           3        Aug-04   Valve & accessories                   Pharmacia       Y 47134089
  Milton Park        3        Jul-04   Refridgerators, cryostorage           Jencons         Y 00326524
                                       Centramate cassette, quattro          Pall
  Milton Park        3        May-04   Pump                                  Corporation     Y 4400465774
  Milton Park        3        Apr-04   Topcount, 2 detector                  Perkin Elmer    Y 5400128782
                                                                             Appleton
  Milton Park        3        Feb-04   Bio-doc - It system                   Woods           Y 088388
                                                                             Becton
  Milton Park        3        Dec-03   FL4 UPG                               Dickinson       Y 40015300
  Milton Park        3        Dec-03   Guava Cytometer                       GRI             Y PRO00455
                                       Mastercycler Thermocycler -
  Milton Park        3        Oct-03   Eppendorf                             VWR             Y 91614147
  Milton Park        3        Jun-03   Total Volume system                   Applikon        Y 24713
                                       2 x Heracell CO2 double                               Y
  Milton Park        3        May-03   Chamber                               Kendro          SLS/83001558
                                                                                             Y
  Milton Park        3        May-03   Herasafe Class II Cabinet             Kendro          SLS/83001758
                                                                                             Y
  Milton Park        3        Apr-03   VAP 3 Unit                            Kendro          SLS/83001255
                                       Radioactive Safety Equip,                             Y
  Milton Park        3        Apr-03   Eppendorff centrifuge                 AMS             GT/0028/000085
</TABLE>

                                        5

<PAGE>

<TABLE>
<S>              <C>         <C>       <C>                                   <C>             <C>
                                       Fluorometer & minicell adapter
  Milton Park        3        Mar-03   kit                                   GRI             Y PRO00403
                                                                             Thermo Life
  Milton Park        3        Mar-03   Hybaid Instruments multiblock         Sciences        Y 842061
                                       Biotechne Hepa & Microplate
  Milton Park        3        Feb-03   Strip Washer                          Jencons         Y 00297563
                                       Biorack Storage Unit, cryoguard,
  Milton Park        3        Feb-03   roller base                           SLS             Y SI25515501
                                       Hybaid Instruments 1 block MBS        Thermo Life
  Milton Park        3        Jan-03   start up kit                          Sciences        Y 836698
                                                                                             Y
  Milton Park        3        Jan-03   Legend Easy Set + accessories         Kendro          SLS/82002705
                                                                             Pall
  Milton Park        3        Dec-02   Quattro pump 1000S                    Corporation     Y 361111
                                                                             Pall
  Milton Park        3        Dec-02   Centramate Package 2                  Corporation     Y 361693
                                                                             Autoimmun
  Milton Park        3        Nov-02   AID Elispot Reader System             Diagnostika     Y AR02114103
  Milton Park        3        Nov-02   Densitometer & accessories            Bio-Rad         Y 320/22027709
                                                                             Amersham
  Milton Park        3        Oct-02   Pump P-950                            Pharmacia       Y 27151076
  Milton Park        3        Sep-02   Protean IEF Cell                      Bio-Rad         Y 320/22021752
                                       MX FLII Optics Carrier &
  Milton Park        3        Sep-02   accessories                           Leica           Y 93466724
                                       Olympus microscope frame &
  Milton Park        3        Sep-02   accessories                           SLS             Y SI24329001
                                       AKTA FPLC system inc
  Milton Park        3        Aug-02   computer & printer                    Rodaris         Y ROD/BV001
                                       Shimadzu UV 2401 PC,
  Milton Park        3        Aug-02   Spectrophotometer etc                 Rodaris         Y ROD/BV002
                                       Washing machine, ice maker,
  Milton Park        3        Jul-02   accessories                           Jencons         Y 00285909
                                       Xograph film processor &
  Milton Park        3        Jun-02   accessories                           Xograph         Y OP/I056750
  Milton Park        3        Jun-02   Gene Pulser II & accessory            Bio-Rad         Y 320/22014464
                                       Computer software - re Oncovex        Canfield
  Milton Park        3        May-02   project                               Clinical
                                       Ultrasonic Processor &
  Milton Park        3        Apr-02   accessories                           Jencons         Y 280112
  Milton Park        3        Apr-02   Legend Easy Set                       Kendro          Y 4025561
  Milton Park        3        Mar-02   Microscope Olympus                    SLS             Y SI21324801
  Milton Park        3        Mar-02   Assorted analytical instruments       Jencons         Y 00278079
                                       Miele Glass Washing Machine &
  Milton Park        3        Mar-02   accessories                           Jencons         Y 00277895
  Milton Park        3        Mar-02   Lightbox, light table                 VWR             Y 91115392
                                       Scintillation counter & cell
  Milton Park        3        Mar-02   harvester                             Packard         Y 57013
  Milton Park        3        Mar-02   Olympus Microscope plus eqpt          SLS             Y SI21324802
  Milton Park        3        Mar-02   Revco Elite Series Upright            Kendro          Y 4024807
  Milton Park        3        Feb-02   Centrifuge 5417R                      VWR             Y 91082496
  Milton Park        3        Feb-02   Minus 80 Freezer                                      Y 4024006
                                       Supply & install additional Cat5e     Computers in
  Milton Park        3        Jan-02   outlets                               the City        Y 4566
                                                                             Red Box Fire
  Milton Park        3        Jan-02   Fire extinguishers                    Control         Y 18794
  Milton Park        3        Jan-02   Installation of telephone system      TSS             Y I/014/02
  Milton Park        3        Jan-02   Fridges for labs                      John Lewis      Y
  Milton Park        3        Jan-02   Equipment for labs - various          Kendro          Y - contract
</TABLE>

                                        6

<PAGE>

<TABLE>
<S>              <C>         <C>       <C>                                   <C>             <C>
  Milton Park        3        Jan-02   Mastercycler gradient, Centrifuge     VWR             Y 91073201
                                       Supply & installation of Cat5e        Computers in
  Milton Park        3        Dec-01   outlets                               the City        Y 4418
  Milton Park        3        Nov-01   Heracell incubator                    Kendro          Y 0004022020
  Milton Park        3        Oct-01   Refractometer                         Merck           Y 90986449
  Milton Park        3        Oct-01   Herasafe Class II Cabinet HS12        Kendro          Y 0004020913
  Milton Park        3        Oct-01   Herasafe Class II Cabinet HS9         Kendro          Y 0004021019
                                       TZ-28 Ti zonal rotor &
  Milton Park        3        Aug-01   conversion kit                        Kendro          Y 0004020110
                                                                             Becton
  Milton Park        3        Aug-01   Facscalibur & accessories             Dickinson       Y 010057564
                                       Reservoir kit, Proflux basic unit
  Milton Park        3        Apr-01   & accessories                         Millipore       Y 74
  Milton Park        3        Apr-01   A-621 F/A Rotor Oncovex               Kendro          Y 0004017808
                                       Spectrophotometer & cell ultra
  Milton Park        3        Mar-01   micro                                 Merck           Y 90812338
  Milton Park        3        Mar-01   Reservoir kit Oncovex                 Millipore       Y 2106385
  Milton Park        3        Dec-00   Lucia IA DVC Camera                   Nikon UK        Y 2042886
  Milton Park        3        Dec-00   Lucia DVC Camera accessories          Nikon UK        Y 2042688
      UCL            3        Nov-00   Heracell Stacked Double Unit          Kendro          Y
      UCL            3        Nov-00   Olympus Microscope plus eqpt          SLS             Y
      UCL            3        Oct-00   Heracell Stacked Double Unit          Kendro          Y
      UCL            3        Sep-00   Millipore eqpt                        Millipore       Y
      UCL            3        Sep-00   Ugo Basile Meter and plate            Linton          Y
                                       Sanyo Gallenkamp upright
      UCL            3        Jun-00   freezer & CO2 backup                  Sanyo           Y 2074933
                                       Proflux M12 Basic unit+reservoir                      Y
      UCL            3        Mar-00   kit                                   Millipore       4033/58428502cr
      UCL            3        Mar-00   Sanitary Manifold+Tubing kit          Millipore       Y 2007139
                                                                             Scientific
      UCL            3        Mar-00   Balance A&D HR-120                    Lab. Supplies   Y 14836901
      UCL            3        Mar-00   Roto rat 8 station & accessories      via UCL         YES
      UCL            3        Mar-00   Opsys MR+Printer                      Dynex           Y 62986
      UCL            3        Feb-00   Leica SM 2000R                        Leica           Y 93215325
      UCL            3        Feb-00   Dry ice tray for Leice SM             Leica           Y 93220416
      UCL            3        Feb-00   Pel 2 Mini holder                     Millipore       Y 2004374
      UCL            3        Feb-00   Stereotactic Drill +Manipulator       Harvard         Y 26396
                                       Small animal sterotaxic
      UCL            3        Dec-99   instrument                            via UCL         NO
                                       Hybridation Oven
      UCL            3        Dec-99   HBMSOV14220                           Hybaid          Y 545925
      UCL            3        Nov-99   Micro4 Controller UPM II              WPI             Y 605623
                                                                             Insight
      UCL            3        Nov-99   Gel system.double sided, vertical     Biotechnology   Y 8119
                                                                             Scientific
      UCL            3        Sep-99   Microscope stero zoom                 Lab. Supplies   Y 12968402
                                                                             Life Sciences
      UCL            3        Sep-99   Mixer/Shaker -Orbital B Denley        Int             Y 770454
                                                                             Amersham
      UCL            3        Sep-99   Power supply x4 +Transphor unit       Pharmacia       Y 97120969
                                                                             Amersham
      UCL            3        Sep-99   Power supply x2                       Pharmacia       Y 97121570
                                       Storage System Biostor                Scientific
      UCL            3        Sep-99   MOL3136                               Lab. Supplies   Y 12965702
                                                                             Insight
      UCL            3        Aug-99   Incubator Shaker, G25 KS              Biotechnology   Y 7029
</TABLE>

                                        7

<PAGE>

<TABLE>
<S>              <C>         <C>       <C>                                   <C>             <C>
                                                                             Scientific
      UCL            3        Aug-99   Icemaker Scotsman AF10-AS             Lab. Supplies   Y 12948301
      UCL            3        Aug-99   Heracell Double Unit x2               Kendro          Y 4003981
      UCL            3        Aug-99   Incubator B12 Function Line           Kendro          Y 4003981
      UCL            3        Aug-99   Centrifuge Superspeed rc -26+         Kendro          Y 4003981
                                                                             Scientific
      UCL            3        Aug-99   Microscope CK40-F Olympus             Lab. Supplies   Y 12968401
                                                                             Scientific
      UCL            3        Aug-99   Biosystem 10 with LN Cylinder         Lab. Supplies   Y 12965701
      UCL            3        Jul-99   Herasafe HS12                         Kendro          Y 4003841
      UCL            3        Jul-99   VIP Freezer -86c MDF-U70V             Sanyo           Y 2066173
      UCL            3        Jul-99   Centrifuge micro 5417c x2             Merck           Y 90271450
                                       Centrifuge, refrigerated Jouan
      UCL            3        Jul-99   CR4.22                                Merck           Y 90271450
                                       Concentrator with pump and
      UCL            3        Jun-99   rotor                                 Merck           Y 90223259
      UCL            3        Jun-99   Centrifuge 5417R with rotor           Merck           Y 90223259
      UCL            3        Jun-99   PCR                                   Merck           Y 90218336
      UCL            3        Apr-99   Incubator/SUB6                        via UCL         NO
                                       New Brunswick Scientific G25
      UCL            3        Jan-99   Incubator Shaker                      Insight         Y 4909
  Milton Park        1        Feb-06   Server and adaptor                    SDT             Y 13095
  Milton Park        1        Jan-06   Servers - Blackberry & email          SDT             Y 13075
                                       Various computer equip (see           Bechtle
  Milton Park        1        Oct-05   invoice)                              Direct          Y SINV079275
  Milton Park        1        Aug-05   Sony Laptop VGN-S4 VP (CSS)           Sony
                                       HP DL380 - Financial Server (for
  Milton Park        1        Jul-05   US)                                   SDT             Y 12955
                                       HP Compaq nx8220-760,                 Bechtle
  Milton Park        1        Jun-05   monitor etc                           Direct          Y SINV072702
                                                                             Bechtle
  Milton Park        1        Jun-05   Sony Vaio (GB)                        Direct          Y SINV073508
  Milton Park        1        Dec-04   Server & accessories                  SDT             Y 12854
                                                                             Eurosource
  Milton Park        1        Nov-04   Sony Vaio Notebook (CL)               IT              Y I002494
  Milton Park        1        Aug-04   Compaq server and extras              SDT             Y 12793
                                       HP DL 380 3.2 Ghz Server &
  Milton Park        1        Jul-04   software                              SDT             Y 12776
                                       D330 MT Computers x 2 (Imm            Bechtle
  Milton Park        1        Jun-04   & JH)                                 Direct          Y SINV056158
  Milton Park        1        Apr-04   Compaq DL320                          SDT             Y 12705
                                                                             Bechtle
  Milton Park        1        Apr-04   Apple PowerMac G4,                    Direct          Y SINV053265
                                       HP Compaq nc4000/ Sony Viao           Bechtle
  Milton Park        1        Jan-04   Z1 RMP                                Direct          Y 47941
                                       M'soft windows/exchange/XP            Software
  Milton Park        1        Nov-03   pro                                   Design Tech     Y 12627
                                                                             Bechtle
  Milton Park        1        Oct-03   HP Colour laser printer               Direct          YSINV044951
                                                                             Software
  Milton Park        1        Oct-03   HP D330 - 1 (Bliu) Computer           Design Tech     Y 12620
                                       HP D330 - 2 (Imm Lab)                 Bechtle
  Milton Park        1        Oct-03   Computer                              Direct          Y SINV045518
                                                                             Software
  Milton Park        1        May-03   Server cabinets                       Design Tech     Y 12518
                                                                             Software
  Milton Park        1        May-03   Rackmount UPS                         Design Tech     Y 12523
</TABLE>

                                        8

<PAGE>

<TABLE>
<S>              <C>         <C>       <C>                                   <C>             <C>
                                       Compaq server, Jukebox &              Software
  Milton Park        1        May-03   software                              Design Tech     Y 12526
                                                                             Software
  Milton Park        1        May-03   Compaq notebook (communal)            Design Tech     Y 12529
                                       Compaq D310 MT & monitor              Software
  Milton Park        1        Feb-03   (blackberry)                          Design Tech     Y 12474
                                       Compaq comp. & monitors               Software
  Milton Park        1        Jan-03   (SW/TP/MW)                            Design Tech     Y 12457
                                       Compaq computer & monitor             Software
  Milton Park        1        Oct-02   (ET)                                  Design Tech     Y 12421
                                       Compaq computer & accessories         Software
  Milton Park        1        Sep-02   (Ymc)                                 Design Tech     Y 12387
                                       Compaq computer & accessories         Software
  Milton Park        1        Sep-02   (RC - L)                              Design Tech     Y 12404
                                                                             Software
  Milton Park        1        Jul-02   Firebox & Soho TC                     Design Tech     Y 12356
                                       Compaq laptop (RS) & 2 PC's           Software
  Milton Park        1        Jun-02   (ST,Anal)                             Design Tech     Y 12342
                                                                             Micro Anvika
  Milton Park        1        Jun-02   Laptop computer (JH)                  (Visa)          Y
                                       5 Compaq                              Software
  Milton Park        1        Apr-02   computers,monitors,software           Design Tech     Y 12292
                                                                             Software
  Milton Park        1        Mar-02   Laptop - TM                           Design Tech     Y 12273
                                                                             Software
  Milton Park        1        Jan-02   3 Compaq D300 & software              Design Tech     Y 12227
                                       Compaq Rack Server &                  Computers in
  Milton Park        1        Dec-01   accessories                           the City        Y 4423
                                       Compaq Rack Server &                  Computers in
  Milton Park        1        Dec-01   accessories                           the City        Y 4422
                                       Compaq stabiliser unit, drawer        Computers in
  Milton Park        1        Dec-01   kit etc                               the City        Y 4421
                                                                             Computers in
  Milton Park        1        Dec-01   Leads various                         the City        Y 4450
                                                                             Computers in
  Milton Park        1        Dec-01   MS Upgrades various, ACT 2000         the City        Y 4417
                                                                             Computers in
  Milton Park        1        Oct-01   Sony Vaio R600 (PAS)                  the City        Y 4200
  Milton Park        4        Sep-05   Filing cabinets & chairs              ISIS            Y (4)
  Milton Park        4        Sep-05   Cabinets & desks                      ISIS            Y (2)
  Milton Park        4        Jul-05   workstation (desks, chairs etc)       ISIS            Y (3)
  Milton Park        4        May-05   4 workstations (desks,chairs etc)     ISIS            Y
  Milton Park        4        Jan-05   4 x 2 drawer fire proof filing cab.   Viking Direct   y
  Milton Park        4        Feb-04   Bisley Side open Tambour              Guilbert        y
  Milton Park        4        Jul-02   Fire cabinet                          Viking Direct   Y
  Milton Park        4        Jun-02   Seating                               Vector          Y
  Milton Park        4        May-02   Office Furniture desks, chairs etc    Viking Direct   Y (2)
  Milton Park        4        Mar-02   Office Furniture desks, chairs etc    Viking Direct   Y (4)
  Milton Park        4        Feb-02   Office Furniture desks, chairs etc    Viking Direct   Y (3)
  Milton Park        4        Jan-02   Office Furniture desks, chairs etc    Viking Direct   Y (5)
  Milton Park        4        Dec-01   Office Furniture desks, chairs etc    Viking Direct   Y (2)
  Milton Park        4        Nov-01   Office Furniture desks, chairs etc    Viking Direct   Y (9)
  Milton Park        4        Oct-01   Office Furniture desks, chairs etc    Viking Direct   Y (6)
                                                                             Oxford
  Milton Park        4        Jul-01   Epson Data projector                  Visuals         Y
  Milton Park        3        Nov-01   Cold room                             IAB 1329,I344 and I352
</TABLE>

                                        9

<PAGE>

<TABLE>
<S>              <C>         <C>       <C>                                   <C>             <C>
                                       Air conditioning units, ducts and
  Milton Park        3        Nov-01   piping                                IAB 1329,I344 and I352
  Milton Park        3        Nov-01   Furniture                             IAB 1329,I344 and I352
                                       Mechanical services and co2
  Milton Park        3        Nov-01   gases                                 IAB 1329,I344 and I352
  Milton Park        3        Nov-01   Circulating fume cupboad              IAB 1329,I344 and I352
</TABLE>

                                       10

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