Document:

<PAGE>
                                                               Exhibit 10.25

                           CHANGE IN CONTROL AGREEMENT

         This Agreement, made and entered into this 3rd day of November 2000, by
and between Endocardial Solutions, Inc., a Minnesota corporation (the
"Company"), with its principal offices at 1350 Energy Lane, Suite 110, St. Paul,
Minnesota, 55108-5254, and __________________ (the "Employee"), residing at 1170
Cushing Circle, #121, St. Paul, Minnesota 55108.

         WHEREAS, this Agreement is intended to specify the financial
arrangements that the Company will provide to the Employee upon the Employee's
separation from employment with the Company under any of the circumstances
described herein; and

         WHEREAS, this Agreement is entered into by the Company in the belief
that it is in the best interest of the Company to provide stable conditions of
employment for the Employee notwithstanding the possibility, threat, or
occurrence of certain types of changes in control, thereby enhancing the
Company's ability to attract and retain highly qualified people;

         NOW, THEREFORE, in lieu of the foregoing recitals and in consideration
of the mutual covenants, promises, payments, and undertakings of the parties
hereto, the parties agree as follows:

         1.   TERM OF AGREEMENT. The Employee shall be employed on an at-will
basis. This Agreement is not, and shall not be construed as, an employment
contract affecting in any way the duration of the Employee's employment or any
terms and conditions thereof except those set forth herein. The Employee and the
Company may terminate their employment relationship at any time, for any reason,
or for no reason.

         2.   TERMINATION OF EMPLOYMENT.

              (a)   PRIOR TO A CHANGE IN CONTROL. Prior to a Change in Control
(as defined in section 3(a) hereof), the Company may terminate the Employee from
employment with the Company at-will with or without Cause (as defined in section
3(c) hereof), at any time.

              (b)   AFTER A CHANGE IN CONTROL.

                    (i)    From and after the date of a Change in Control (as
defined in section 3(a) hereof), during the term of this Agreement, the Company
shall not terminate the Employee from employment with the Company except as
provided in this section 2(b), or as a result of the Employee's Disability (as
defined in section 3(d) hereof) or his death.

                                      -1-

<PAGE>

                    (ii)   From and after the date of a Change in Control (as
defined in section 3(a) hereof), during the term of this Agreement, the Company
shall have the right to terminate the Employee from employment with the Company
at any time for Cause (as defined in section 3(c) hereof), by written notice to
the Employee, specifying the particulars of the conduct of the Employee forming
the basis for such termination.

                    (iii)  From and after the date of a Change in Control (as
defined in section 3(a) hereof), during the term of this Agreement: (a) the
Company shall have the right to terminate the Employee's employment without
Cause (as defined in section 3(c) hereof), at any time; and (b) the Employee
shall, upon the occurrence of such termination by the Company without Cause or
upon the voluntary termination of the Employee's employment by the Employee for
Good Reason (as defined in section 3(b) hereof), be entitled to receive the
benefits provided in section 4 hereof. The Employee shall evidence a voluntary
termination for Good Reason by written notice to the Company given within ten
(10) days after the date of the occurrence of any event that the Employee knows
or should reasonably have known constitutes Good Reason for voluntary
termination. Such notice need only identify the Employee and set forth in
reasonable detail the facts and circumstances claimed by the Employee to
constitute Good Reason. Any notice given by the Employee pursuant to this
section 2 shall be effective ten (10) days after the date it is given by the
Employee.

         3.   DEFINITIONS.

              (a)   A "Change in Control" shall mean:

                    (i)    A change in control of a nature that would be
required to be reported in response to Item 6(e) of Schedule 14A of Regulation
14A promulgated under the Securities Exchange Act of 1934, as amended (the
"Exchange Act"), whether or not the Company is then subject to such reporting
requirement;

                    (ii)   The public announcement (which, for purposes of this
definition, shall include, without limitation, a report filed pursuant to
Section 13(d) of the Exchange Act) by the Company or any "person" (as such term
is used in Sections 13(d) and 14(d) of the Exchange Act) that such person has
become the "beneficial owner" (as defined in Rule 13d-3 promulgated under the
Exchange Act) directly or indirectly, of securities of the Company representing
twenty percent (20%) or more of the combined voting power of the Company's then
outstanding securities;

                    (iii)  The Continuing Directors (as defined in section 3(e)
hereof) cease to constitute a majority of the Company's Board of Directors;

                    (iv)   The shareholders of the Company approve: (a) any
consolidation or merger of the Company in which the Company is not the
continuing or surviving corporation or pursuant to which shares of Company stock
would be converted into cash, securities, or other property, other than a merger
of the Company

                                      -2-

<PAGE>

in which shareholders immediately prior to the merger have the same
proportionate ownership of stock of the surviving corporation immediately after
the merger; (b) any sale, lease, exchange, or other transfer (in one transaction
or a series of related transactions) of all or substantially all of the assets
of the Company; or (c) any plan of liquidation or dissolution of the Company; or

                    (v)    The majority of the Continuing Directors (as defined
in section 3(e) hereof) determine in their sole and absolute discretion that
there has been a Change in Control of the Company.

              (b)   "Good Reason" shall mean the occurrence of any of the
following events, except for the occurrence of such an event in connection with
the termination or reassignment of the Employee's employment by the Company for
Cause (as defined in section 3(c) hereto), for Disability (as defined in section
3(d) hereof), or for death:

                    (i)    The assignment to the Employee of employment
responsibilities which are not of comparable responsibility and status as the
employment responsibilities held by the Employee immediately prior to a Change
in Control (as defined in section 3(a) hereof);

                    (ii)   Any unreasonable reduction by the Company in the
Employee's base salary as in effect immediately prior to a Change in Control (as
defined in section 3(a) hereof);

                    (iii)  The failure by the Company to obtain, as specified in
section 5(a) hereof, an assumption of the obligations of the Company to perform
this Agreement by any successor to the Company;

                    (iv)   The Company's requiring the Employee to be based at a
location that is in excess of 50 miles from the location of the Employee's
principal office immediately prior to a Change in Control (as defined in section
3(a) hereof); or

                    (v)    Any other material breach of this Agreement by the
Company which is not cured within thirty (30) days after written notice thereof
from the Employee.

              (c)   "Cause" shall mean termination by the Company of the
Employee's employment based upon:

                    (i)    Repeated violations by the Employee of any of his
duties or his repeated failures or omissions to carry out lawful and reasonable
orders which, in the reasonable judgment of the Company, are willful and
deliberate and which are not cured within a reasonable period after the
Employee's receipt of written notice thereof from the Company;

                                      -3-

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                    (ii)   Any act or acts of personal dishonesty by the
Employee which are intended to result in the personal enrichment of the Employee
at the expense of the Company;

                    (iii)  Any willful and deliberate misconduct that is
materially and demonstrably injurious to the Company; or

                    (iv)   Any criminal indictment, presentment, or conviction
for a felony, whether or not the Company is the victim of such offense.

              (d)   "Disability" shall mean Employee's total disability which
results in Employee's inability to perform the essential functions of Employee's
position, with or without reasonable accommodation, provided Employee has
exhausted Employee's entitlement to any applicable leave, if Employee desires to
take and satisfies all eligibility requirements for such leave.

              (e)   "Continuing Director" shall mean any person who is a
member of the Board of Directors of the Company, while such person is a member
of the Board of Directors, who is not an Acquiring Person (as defined herein) or
an Affiliate or Associate (as defined herein) of an Acquiring Person, or a
representative of an Acquiring Person or any such Affiliate or Associate, and
who:

                    (i)    was a member of the Board of Directors on the date of
this Agreement as first written above; or

                    (ii)   subsequently becomes a member of the Board of
Directors, if such person's initial nomination for election or initial election
to the Board of Directors is recommended or approved by a majority of the
Continuing Directors. For purposes of this section 3(e), "Acquiring Person"
shall mean any "person" (as such term is used in sections 13(d) and 14(d) of the
Exchange Act) who or which, together with all Affiliates and Associates of such
person, is the "beneficial owner" (as defined in Rule 13d-3 promulgated under
the Exchange Act), directly or indirectly, of securities of the Company
representing twenty percent (20%) or more of the combined voting power of the
Company's then outstanding securities, but shall not include the Company, any
subsidiary of the Company, or any employee benefit plan of the Company, or of
any subsidiary of the Company, or any entity holding shares of common stock
organized, appointed, or established for, or pursuant to the terms of, any such
plan; and "Affiliate" and "Associate" shall have the respective meanings
described to such terms in Rule 12b-2 promulgated under the Exchange Act.

         4.   BENEFITS UPON TERMINATION UNDER SECTION 2(b)(iii).

              (a)   Upon the termination (voluntary or involuntary) of the
employment of the Employee pursuant to section 2(b)(iii) hereof, the Company
shall pay to the Employee, in lieu of any further base salary or bonus
payments to the

                                      -4-

<PAGE>

Employee for periods subsequent to the date that the termination of the
Employee's employment becomes effective, as severance pay, payments as
follows:

                    (i)    if the termination pursuant to section 2(b)(iii)
hereof following a Change in Control (as defined in section 3(a) hereof) occurs
during the first twelve (12) months following a Change in Control (as defined in
section 3(a) hereof), payments equal to twelve (12) times the Employee's monthly
base salary;

                    (ii)   if the termination pursuant to section 2(b)(iii)
hereof following a Change in Control (as defined in section 3(a) hereof) occurs
more than twelve (12) months after a Change in Control (as defined in section
3(a) hereof), the Employee will not be entitled to any payments pursuant to this
section 4.

              (b)   For purposes of this section 4, "the Employee's monthly
base salary" shall mean the Employee's monthly base salary as in effect in the
month preceding the month in which the termination becomes effective or as in
effect in the month preceding the Change in Control, whichever is higher.

              (c)   All payments to the Employee subject to this section 4
shall be paid, in the sole discretion of the Company, in a lump sum or
periodically in accordance with the Company's normal payroll practices in effect
from time-to-time. All payments to the Employee subject to this section 4 shall
be subject to any applicable payroll or other taxes required by law to be
withheld.

              (d)   The Employee shall not be required to mitigate the amount
of any payment provided for in this section 4 by seeking other employment or
otherwise. The amount of any payment provided in this section 4 shall not be
reduced by any compensation earned by the Employee as a result of any employment
by an employer.

         5.       SUCCESSORS AND BINDING AGREEMENT.

              (a)   The Company will require any successor (whether direct or
indirect) by purchase, merger, consolidation, or otherwise to all or
substantially all of the business and/or of the assets of the Company to
expressly assume and agree to perform this Agreement in the same manner and to
the same extent that the Company would be required to perform it if no such
succession had taken place. Failure of the Company to obtain such agreement
prior to the effectiveness of any such succession shall be a breach of this
Agreement and shall entitle the Employee to compensation from the Company in the
same amount and on the same terms as the Employee would be entitled hereunder if
the Employee terminated his employment after a Change in Control for Good
Reason, except that, for purposes of implementing the foregoing, the date on
which any such succession becomes effective shall be deemed the date that the
termination of the Employee's employment becomes effective. As used in this
Agreement, "Company" shall mean the Company and any successor to its business
and/or assets which executes and delivers the Agreement provided for in this
section

                                      -5-

<PAGE>

5(a) or which otherwise becomes bound by all the terms and provisions of
this Agreement by operation of law.

              (b)   This Agreement is personal to the Employee, and the
Employee may not assign or transfer any part of his rights or duties hereunder,
or any compensation due to him hereunder, to any other person. Notwithstanding
the foregoing, this Agreement shall inure to the benefit of, and be enforceable
by, the Employee's personal or legal representatives, executors, administrators,
heirs, distributees, devisees, and legatees.

         6.   LIMITATION OF DAMAGES. If for any reason the Employee believes the
severance provisions of this Agreement have not been properly adhered to by the
Company, and if, pursuant to section 7 hereof, it is determined that the Company
has not, in fact, properly adhered to the severance provisions of this
Agreement, the sole and exclusive remedy to which the Employee is entitled is
the severance payment to which he is entitled under the provisions of this
Agreement.

         7.   DISPUTE RESOLUTION. Any controversy, claim, or dispute arising out
of or relating to the making, performance, breach, termination, expiration,
application, or meaning of this Agreement shall be resolved exclusively by
arbitration before the American Arbitration Association in Minneapolis,
Minnesota, pursuant to the American Arbitration Association's rules then in
effect.

              (a)   The decision of the arbitrator(s) shall be final and
binding on both parties. Judgment on the award rendered by the arbitrator(s) may
be entered in any court having jurisdiction thereof. In the event of submission
of any dispute to arbitration, each party shall, not later than thirty (30) days
prior to the date set for hearing, provide to the other party and to the
arbitrator(s) a copy of all exhibits upon which the party intends to rely at the
hearing and a list of all persons whom the party intends to call as witnesses at
the hearing.

              (b) The arbitrator(s) shall strictly adhere to the sole and
exclusive remedy set forth in section 6 hereof and may not award or assess
punitive damages against either party.

              (c)   Each party shall bear its own costs and expenses of the
arbitration and one-half (1/2) of the fees and costs of the arbitrator(s).

         8.   MODIFICATION: WAIVER. No provisions of this Agreement may be
modified, waived, or discharged unless such waiver, modification, or discharge
is agreed to in a writing signed by the Employee and such officer as may be
specifically designated by the Board of Directors of the Company. No waiver by
either party hereto at any time of any breach by the other party hereto of, or
compliance with, any condition or provision of this Agreement to be performed by
such other party shall be

                                      -6-

<PAGE>

deemed a waiver of similar or dissimilar provisions or conditions at the same or
at any prior or subsequent time.

         9.   NOTICE. All notices, requests, demands, and all other
communications required or permitted by either party to the other party by this
Agreement (including, without limitation, any notice of termination of
employment) shall be in writing and shall be deemed to have been duly given when
delivered personally or received by certified or registered mail, return receipt
requested, postage prepaid, at the address of the other party as first written
above (directed to the attention of the Board of Directors in the case of the
Company). Either party hereto may change its address for purposes of this
section 9 by giving fifteen (15) days' prior written notice to the other party
hereto.

         10.  SEVERABILITY. If any term or provision of this Agreement or the
application hereof to any person or circumstances shall to any extent be invalid
or unenforceable, the remainder of this Agreement or the application of such
term or provision to persons or circumstances other than those as to which it is
held invalid or unenforceable shall not be effected thereby, and each term and
provision of this Agreement shall be valid and enforceable to the fullest extent
permitted by law.

         11.  GOVERNING LAW.  This Agreement has been executed and delivered in
the State of Minnesota and shall in all respects be governed by, and construed
and enforced in accordance with, the laws of the State of Minnesota, including
all matters of construction, validity, and performance.

         12.  EFFECT OF AGREEMENT: ENTIRE AGREEMENT. The Company and the
Employee understand and agree that this Agreement is intended to reflect their
agreement only with respect to the subject matter hereof and is not intended to
create any obligation on the part of either party to continue employment. This
Agreement supersedes any and all other oral or written agreements or policies
made relating to the subject matter hereof and constitutes the entire agreement
of the parties relating to the subject matter hereof; provided that this
Agreement shall not supersede or limit in any way the Employee's rights under
any benefit plan, program, or arrangements in accordance with their terms.

                                      -7-

<PAGE>

         IN WITNESS WHEREOF, the Company and the Employee have executed this
Agreement as of the date first written above.

                                              ENDOCARDIAL SOLUTIONS, INC.

                                              By   /s/ James W. Bullock
                                              -----------------------------

                                              Its  President and Chief
                                              -----------------------------
                                                   Executive Officer
                                              -----------------------------

                                              [EMPLOYEE]

                                              ----------------------------

                                      -8-<PAGE>

                                                                   Exhibit 10.26
                           LEASE AMENDMENT NUMBER FIVE

         THIS LEASE AMENDMENT NUMBER FIVE is made this second day of August,
1999, by and between the Port Authority of the City of St. Paul, a public body
corporate and politic, created pursuant to Chapter 469 of Minnesota Statutes,
herein called "Lessor," and Endocardial Solutions, Inc., a Delaware corporation,
herein called "Tenant."

                                    RECITALS

         WHEREAS, by a Lease dated September 15, 1993, Endocardial Therapeutics,
Inc. did lease from Lessor Suite 110E on the first floor in that certain office
building known as Energy Park Place East Building, located at 1350 Energy Lane,
St. Paul, Minnesota; and by the Lease Modification and Extension Agreement dated
February 6, 1995, Tenant did lease Suite 107E and extended term; and by the
Lease Amendment Number Two dated May 16, 1995, the tax clause was modified; and
by Lease Amendment Number Three dated June 4, 1996, Tenant did Lease Suite 113E
and extended term; and by a notice letter dated March 31, 1997 and acceptance
letter dated June 16, 1997, Tenant exercised its option to extend, and by Lease
Amendment Number Four dated January 23, 1998, Tenant did lease Suite 207. Said
space consists of approximately 21,535 rentable square feet, is shown in Exhibit
A attached to said Lease, and is herein called the "Premises" and the "Existing
Space."

         WHEREAS, the term of said Lease expired on March 31, 1999 and continued
month-to-month thereafter; and

         WHEREAS, the parties wish to extend term, add certain space to the
Premises, and make certain changes to said Lease.

                                    AGREEMENT

         NOW, THEREFORE, in consideration of the mutual covenants contained
herein and in said Lease, the parties hereto agree as follows:

         1.   ENLARGEMENT OF PREMISES: Effective as of October 1, 1999, the
description of the Premises contained in said lease is amended so as to add
Suite 106E, consisting of approximately 2,138 rentable square feet, and
effective as of October 1, 1999, Suite 105E is added, consisting of 4,893
rentable square feet, and effective October 1, 1999, Suite 104E is added,
consisting of 1,834 rentable square feet, and effective September 30, 1999 Suite
207E is subtracted consisting of 4,056 rentable square feet, and hereinafter
called the "Additional Space." As of October 1, 1999, the total space
(hereinafter called the "Enlarged Premises") leased to Tenant under said Lease
shall consist of a total area of approximately 26,344 rentable square feet. The
Enlarged Premises are generally shown on the floor plan attached hereto as
Exhibit "A," which exhibit is made a part hereof by this reference. As of
October 1, 1999, that certain Exhibit "A" attached to said Lease is hereby
superseded (by Exhibit "A" attached hereto) and of no further force and effect.

                                      -1-

<PAGE>

         2.   NET BASE RENT: Effective as of the dates below, the net base rent
payable shall be as follows for the extended term:

<TABLE>
<CAPTION>

---------------------------------------------------------------------------------
                                                                     NET BASE
        DATES                    SUITE                  SF         RENT/RSF/YR
---------------------------------------------------------------------------------
   <S>                       <C>                     <C>          <C>
    4/1/99-9/30/99           110E/107E/113E           17,479          $9.00
                                  207E                 4,056          $9.00
                                                      ------
                                 Total                21,535
---------------------------------------------------------------------------------
   10/1/99-3/31/00           110E/107E/113E           17,479          $9.00
                             104E/105E/106E            8,865          $9.00
                                                      ------
                                 Total                26,344
---------------------------------------------------------------------------------
    4/1/00-3/31/01           110E/107E/113E           17,479          $9.50
                             104E/105E/106E            8,865          $9.50
                                                      ------
                                 Total                26,344
---------------------------------------------------------------------------------
</TABLE>

The base rent, as increased herein, shall continue to be payable in advance by
the first of each month and subject to operating expenses and taxes as well as
its separately metered utilities. Tenant is solely responsible for its own
janitorial and garbage removal and disposal for the Enlarged Premises. If the
Additional Space is added to the Premises on a date prior to October 1, 1999,
the resulting increase in rent shall be prorated for such partial month.

              3.    EXTENSION  OF LEASE  TERM:  The term of the Lease is
hereby extended for a period of two (2) years, from April 1, 1999 to and
including March 31, 2001.

              4.    CONDITION OF EXISTING AND ADDITIONAL SPACE/TENANT'S WORK:
Tenant is presently in possession of the Existing Premises and accepts same in
its present condition as of the date hereof. Tenant has inspected the Additional
Space including but not limited to HVAC capacity and distribution, electrical
capacity and distribution, and telecommunication capacity and distribution and
accepts same as of the date hereof. Any improvements to be done by Tenant to the
Additional Space shall be at Tenant's sole cost and expense, and shall be
performed in accordance with the provisions of said Lease. Tenant agrees that
any additional HVAC modifications must comply with Energy Center regulations.
Any supplemental, non Energy Center connected, existing HVAC units must remain
as designed prior to Tenant's occupancy. Pursuant to Sections 5 and 6 of this
Lease and provided Lessor approves plan, and contractors are licensed, bonded
and insured, Tenant shall proceed to complete certain improvements to Suites
106E, 105E and 104E as shown on attached Exhibit E. Provided Tenant is not in
default, and in consideration of Tenant accepting the Premises in "as-is"
condition and completing its own tenant improvements, Lessor agrees to reimburse
Tenant for the cost of building standard improvements, including architectural
fees, permits, performance and payment bonds, demolition, and construction
financing, prior to November 1, 1999. The tenant improvement reimbursement shall
be given to Tenant in the form of Net Base Rent Abatement. Upon completion of
tenant improvements, Tenant shall present Lessor with copies of all invoices,
contractor unconditional lien releases and a complete set of "As-Built"
drawings. Then, Tenant and Lessor agree to execute an amendment to this Lease
setting forth the amount of Rent Abatement which shall be equivalent to the
actual amount Tenant spends on building standard improvements for Suites 106E,
105E and 104E, not to exceed $57,497.00 in Net Base Rent. If Tenant does not
improve Suites 106E, 105E and 104E by said amount by November 1, 1999,

                                      -2-

<PAGE>

said rent credit is null and void. Any improvement costs amount over this
allowance is Tenant's sole responsibility.

          5.  FINANCIAL STATEMENT: Attached as Exhibit "F" are Tenant's updated
audited corporate financial statements.

          6.  MISCELLANEOUS:

              (a)   The provisions of this Lease Amendment shall be fully
applicable to the Enlarged Premises and shall remain in full force and effect
for the duration of the term of said Lease, as extended herein.

              (b)   Except as otherwise set forth herein, all of the terms and
conditions of said Lease shall remain in full force and effect, and shall be
fully applicable to the Additional Space as well as the Existing Space,
throughout the duration of the term of said Lease, as extended herein. Said
Lease, as amended herein, constitutes the entire agreement between the parties
hereto, and no further modification of said Lease shall be binding unless
evidenced by an agreement in writing signed by Lessor and Tenant.

              (c)   The captions and paragraph numbers appearing in the
Amendment are inserted only as a matter of convenience and in no way define,
limit, construe, affect or describe the scope or intent of the provisions in
this Amendment.

         7.   This Lease Amendment Number Five will not be in effect until duly
signed by Lessor and Tenant.

IN WITNESS WHEREOF, Lessor and Tenant have executed this Lease Amendment Number
Five as of the day and year first above written.

LESSOR:                                       TENANT:

PORT AUTHORITY OF THE CITY OF SAINT PAUL      ENDOCARDIAL SOLUTIONS, INC.

By:  /s/ Kenneth R. Johnson                   By:  /s/ Leota Pearson
    ---------------------------------            -----------------------------
Its: President                                Its: VP Finance & CFO
    ---------------------------------            -----------------------------

By:                                           By:
    ---------------------------------            -----------------------------
Its:                                          Its:
    ---------------------------------            -----------------------------

--------------------------------------------------------------------------------
CONSULT YOUR ATTORNEY: This document has been prepared for approval by your
attorney. No representation or recommendation is made by Broker as to the legal
sufficiency, legal effect, or tax consequence of this document or the
transaction to which it relates. These are questions for your attorney and
financial advisors.
--------------------------------------------------------------------------------

                                      -3-

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