Document:

STATEMENT OF WORK NO. 24

 Exhibit 10.1.1 

 

							
	Statement of Work No. 24 Revision 6 (NE)
	SOW:	 		 	 	 	No
		 		 	ü  	 	Yes

 Pursuant to Instruction 2 to Item 601 of Regulation S-K, NeuStar, Inc. has filed an agreement with the North
American Portability Management LLC, as successor to Northeast Carrier Acquisition Company, LLC, which is one of seven agreements that are substantially identical in all material respects other than the parties to the agreements. North American
Portability Management, LLC succeeded to the interests of Northeast Carrier Acquisition Company, LLC and each of the other entities listed below. The following list identifies the other parties to the six agreements that have been omitted pursuant
to Instruction 2 to Item 601: 
  

	 	•	 	 LNP, LLC (Midwest) 

  

	 	•	 	 Southwest Region Portability Company, LLC 

  

	 	•	 	 Western Region Telephone Number Portability, LLC 

 

	 	•	 	 Southeast Number Portability Administration Company, LLC 

 

	 	•	 	 Mid-Atlantic Carrier Acquisition Company, LLC 

  

	 	•	 	 West Coast Portability Services, LLC 

  

 
 AMENDED AND RESTATED 
 STATEMENT OF WORK NO. 24 
 FOR 

CONTINUING CERTIFICATION TESTING (CCT) 
 CONFIDENTIAL 

							
	Statement of Work No. 24 Revision 6 (NE)
	SOW: 	 		 	 	 	No
		 		 	ü  	 	Yes

  

 AMENDED AND RESTATED STATEMENT OF WORK 

FOR 

CONTINUING CERTIFICATION TESTING (CCT) 
  

	1.	PARTIES & EFFECTIVENESS 

 This
Revision 6 (the “Revision”) to Statement of Work No. 24 (this “SOW”) amends and restates in its entirety the SOW in effect immediately prior the SOW Effective Data (as that term is defined below),
and is entered into pursuant to Article 13 and Article 30 of, and upon execution shall be a part of, the Contractor Services Agreement for Number Portability Administration Center/Service Management System, as amended and in effect immediately prior
to the SOW Revision Effective Date (each such agreement referred to individually as the “Master Agreement” and collectively as the “Master Agreements”) by and between NeuStar, Inc.
(“Contractor”) and the North American Portability Management LLC, a Delaware limited liability company (the “Customer”), as the successor in interest to and on behalf of the Northeast Carrier
Acquisition Company, LLC (the “Subscribing Customer”). 
  

	2.	EFFECTIVENESS AND SUBSCRIBING CUSTOMERS 

This Revision of the SOW shall be effective as of the last date of execution below (the “SOW Revision Effective Date”),
conditioned upon execution by Contractor and Customer on behalf of all the limited liability companies listed below for the separate United States Service Areas (the “Subscribing Customers”). 

 

	 	•	 	 LNP, LLC (Midwest) 

  

	 	•	 	 Mid-Atlantic Carrier Acquisition Company, LLC 

  

	 	•	 	 Northeast Carrier Acquisition Company, LLC 

  

	 	•	 	 Southeast Number Portability Administration Company, LLC 

 

	 	•	 	 Southwest Region Portability Company, LLC 

  

	 	•	 	 West Coast Portability Services, LLC 

  

	 	•	 	 Western Region Telephone Number Portability, LLC 

 The number in the upper left-hand corner refers to this Statement of Work. Capitalized terms used herein without definition or which do not specifically reference another agreement shall have the meanings
as defined in the Master Agreement. 

  
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	Statement of Work No. 24 Revision 6 (NE)
	SOW: 	 		 	 	 	No
		 		 	ü  	 	Yes

  

	3.	APPLICABLE DOCUMENTS 

 The following
internal documents are applicable to the Additional Services contemplated under this SOW: 
  

			
	  ü  	  	Requirements Traceability Matrix
	ü	  	System Design
	ü	  	Detailed Design
	ü	  	Integration Test Plan
	ü	  	System Test Plan
	ü	  	NPAC Software Development Process Plan
	ü	  	User Documentation

 Effective on the SOW Completion Date (defined below), the term Specifications as used in the Master Agreements shall mean
the Specifications as defined therein and as modified and amended pursuant to Statements of Work under the Master Agreements through and including this Statement of Work. 

 

	4.	IMPACTS ON MASTER AGREEMENT 

  

			
	None	  	Master Agreement
	None	  	Exhibit B Functional Requirements Specification
	None	  	Exhibit C Interoperable Interface Specification
	None	  	Exhibit E Pricing Schedules
	None	  	Exhibit F Project Plan and Test Schedule
	None	  	Exhibit G Service Level Requirements
	None	  	Exhibit H Reporting and Monitoring Requirements
	None	  	Exhibit J User Agreement Form
	None	  	Exhibit K External Design
	None	  	Exhibit L Infrastructure/Hardware
	None	  	Exhibit M Software Escrow Agreement
	None	  	Exhibit N System Performance Plan for NPAC/SMS Services
	None	  	Disaster Recovery
	None	  	Back Up Plans
	None	  	Gateway Evaluation Process (Article 32 of Master Agreement)

  

	5.	SCOPE OF ADDITIONAL SERVICES 

 Contractor
shall perform the Additional Services set forth herein. The Additional Services under this SOW consist exclusively of the activities set forth in this Article 5. 
  

	 	5.1	No Enhancements 

 The Additional Services
set forth in this SOW are not an Enhancement to the NPAC/SMS as defined under the Master Agreement. 
  

	 	5.2	Purpose 

 The Additional Services ensure
that all Users are maintaining a system that does not impact the NPAC/SMS and other providers when the NPAC/SMS software application is changed or modified as required under any other statement of work. Users’ systems must support new NPAC/SMS
Software releases subject to Change Orders issued by the North American 

  
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	Statement of Work No. 24 Revision 6 (NE)
	SOW: 	 		 	 	 	No
		 		 	ü  	 	Yes

  

 
Numbering Council (NANC) and incorporated into statements of work negotiated between Contractor the Customer. User systems that do not meet these requirements may be a significant
inhibitor of systems’ operations and efficiency for local number portability across the industry. This Article defines the requirements for ensuring that all Users are maintaining a system that does not adversely impact the NPAC/SMS and other
providers when the NPAC/SMS software application is changed. This SOW also defines the process for ensuring certification for NPAC/SMS Software releases agreed to by the Subscribing Customers and as implemented by Contractor. 

 

	 	5.3	Changes Resulting from Revision 6 

 The
SOW is revised by this Revision to reflect the decision by the LNPA Working Group, at its March 14, 2012 meeting, to eliminate vendor Interoperability (ITP) testing and replace it with vendor Turn-Up Testing (TUT). That is, both
local system developers and SOA/LSMS Users each separately will perform the complete set of required Turn-Up test cases. The term “Continuing Certification Process” (CCP) is replaced with the term “Continuing Certification
Testing” (CCT). 
  

	 	5.4	Continuing Certification Testing 

 Each
local system (i.e., Service Order Administration [SOA] or Local Service Management System [LSMS]) developer and User shall satisfactorily complete CCT provided for in each SOW. A User shall not establish or maintain an active association with the
NPAC following the production release of an NPAC/SMS Software version subject to each SOW, unless and until both the local system developer and the User have satisfactorily completed the CCT. The foregoing requirement to satisfactorily complete CCT
applies to all scenarios described in Section 5.7 below, except scenario (a). For a given SOA or LSMS system configuration, local system developer testing must be completed before User testing is begun. 

 

	 	5.5	Initial Suspension 

 If both local system
developer and User do not satisfactorily complete such CCT at least five (5) calendar days prior to date on which a new version of the NPAC/SMS Software is implemented in any Service Area, as set forth in the applicable SOW Project Plan of the
statement of work for the implementation of such a release, and such User has not voluntarily agreed to suspend its association with the NPAC/SMS at least one (1) calendar day prior to the new production release date, then Contractor may
suspend the User’s association and User shall not be allowed to re-establish its association unless or until both User and its local system developer have completed CCT (the “Initial Suspension”). Contractor shall notify the
appropriate Subscribing Customer or Project Executive of the date such Initial Suspension occurred. During any suspension of User’s association in accordance with this SOW, User shall remain obligated with respect to all charges as would
otherwise be charged under the Master Agreement and User Agreement. 

  
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 CONFIDENTIAL 

							
	Statement of Work No. 24 Revision 6 (NE)
	SOW: 	 		 	 	 	No
		 		 	ü  	 	Yes

  

 If a User fails to complete CCT within the time allotted, as set forth in the applicable SOW Project
Plan, and Contractor has suspended such User’s association, then Contractor shall notify User that User has thirty (30) calendar days (the “Initial Suspension Period”), from receipt of such notification in which to
complete CCT. During the Initial Suspension Contractor shall furnish one (1) bulk data download (“BDD”) per applicable NPAC/SMS Service Area per calendar day without charge and User shall accept and install such BDD. Upon
expiration of the Initial Suspension period, Contractor shall have the right to exercise one (1) of the following options (Contractor may consult with Subscribing Customers on a case-by-case basis about which option is selected): 

Option 1 - Continued Suspension 
 After the Initial Suspension period Contractor may continue the User’s applicable User Agreement by providing notice thereof no later than the end of the Initial Suspension Period, and thus continue
providing User with BDDs (the “Continued Suspension Period”). In such a case, Contractor shall provide one (1) BDD per applicable NPAC/SMS Service Area per calendar day for a fee (see Attachment A for pricing) and User shall
accept and install such BDD. 
 Option 2 - Termination 

The User’s applicable User Agreement shall terminate if Contractor (a) does not elect during the Initial Suspension Period to
continue the User Agreement or (b) provides notice of termination during any Continued Suspension Period. User shall be charged and be liable for all fees associated with subsequently establishing service as a new User. 

 

	 	5.6	Amendment to Section 10.1(e) of User Agreement  

 Each User Agreement is hereby amended to add a new paragraph (e) to Section 10.1 (concerning termination), reading, in its entirety, as follows: 

(e) immediately, upon the expiration of a thirty (30) day period following receipt of written notice from Contractor that the User
has not satisfactorily completed Continuing Certification Testing, unless Contractor elects, at its option, to continue the User Agreement, notice of which must be provided to the User no later than the end of the forgoing thirty (30) day
period, until Contractor otherwise terminates the User Agreement upon written notice. 
  

	 	5.7	Requirements for Turn-Up Testing 

 TUT,
which includes both new NPAC/SMS Software release functionality testing and regression testing, must be performed on a developer’s local system software and on a User’s local system software anytime a change is made to the interface (GDMO
or ASN.1) of either the NPAC/SMS 

  
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 CONFIDENTIAL 

							
	Statement of Work No. 24 Revision 6 (NE)
	SOW: 	 		 	 	 	No
		 		 	ü  	 	Yes

  

 
or the local system. In the event that the interface change is initiated by the NPAC/SMS, both the local system developers and Users shall perform Turn-Up testing on each version of the local
system software that a User potentially may use with the new NPAC/SMS interface. However, in the case where the User also is the local system developer, the second round of Turn-Up testing which User otherwise would perform is not required as part
of the Continuing Certification Testing. 
 The following sets forth the required level of testing for specific scenarios: 

(a) When a local product (SOA/LSMS) is compiled with the current interface model, and a new local feature (SOA/LSMS feature) is
implemented that does NOT involve a change in the use of the interface model, and the NPAC/SMS is compiled with the current model, then Turn-Up Testing is optional. Test cases to be performed at the discretion of local system developers and Users.
In this situation standard regression test cases shall be performed. 
 (b) When a local product (SOA/LSMS) is compiled
with the current interface model, and no new local features are implemented that involve the interface, and the NPAC/SMS is compiled with the new interface model, then Turn-Up Testing by both local system developers and Users is required. In this
situation, standard regression test cases shall be performed. 
 (c) When a local product (SOA/LSMS) is compiled with the
new interface model, and no new local features are implemented that involve the interface, and the NPAC/SMS is compiled with the new interface model, then Turn-Up Testing by both local system developers and Users is required. In this situation,
standard regression test cases shall be performed. 
 (d) When a local product (SOA/LSMS) is compiled with the new
interface model, and new local features are implemented that involve the interface, and the NPAC/SMS is compiled with the new interface model, then Turn-Up Testing by both local system developers and Users is required. In this situation, standard
regression test cases and new functionality test cases shall be performed. 
 (e) When a local product (SOA/LSMS) is
compiled with the current interface model, and new local features are implemented that involve the interface, and the NPAC/SMS is compiled with the current model, then Turn-Up Testing by both local system developers and Users is required. In this
situation, standard regression test cases and new functionality test cases shall be performed. 
 (f) When the operating
system software of a local product (SOA/LSMS ) is upgraded, and this results in any OSI stack or CMIP toolkit change, then Turn-Up Testing by both local system developers and Users is required. In this situation, standard regression test
cases shall be performed. 

  
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 CONFIDENTIAL 

							
	Statement of Work No. 24 Revision 6 (NE)
	SOW: 	 		 	 	 	No
		 		 	ü  	 	Yes

  

 (g) When the operating system of a local product (SOA/LSMS) is changed (e.g. OS vendor A
to OS vendor B), then Turn-Up Testing by both local system developers and Users is required. In this situation, standard regression test cases shall be performed. 
 (h) When the hardware of a local product (SOA/LSMS) is changed, then Turn-Up Testing by both local system developers and Users is required. In this situation, standard regression test cases
shall be performed. 
  

	6.	OUT OF SCOPE SERVICES 

 This SOW contains
the agreed-upon terms and conditions that shall govern Contractor’s performance of the Additional Services described herein. The Additional Services provided for in this SOW and for which Contractor shall be compensated in accordance with
Section 6, herein, shall not be interpreted, implied, or assumed to include any other service(s), including additional or changed services, not specifically described in Article 5, Scope of Additional Services. Any and all requested or required
services or change orders (hereinafter “Out of Scope Services”) may be provided in accordance with the Master Agreement and, specifically, Article 13. 

 

	7.	PROJECT SCHEDULE 

 The schedule set forth
in the following table is a summary of tasks and time frames for implementation: 
  

					
	 Phase
	  	 Summary Milestone
	  	 Interval

			
	 Phase 0.0
	  	Statement of Work Effective	  	Week 0
			
	 Phase 1.0
	  	Develop Communication and Education Plan for local system (SOA/LSMS) Developers and Users	  	Week 1
			
	 Phase 2.0
	  	Notify Subscribing Customers of CCT Procedures	  	Week 2

  

	8.	PRICING 

  

	 	8.1	Obligation 

 Upon execution of this
Revision, Contractor shall be entitled to full compensation for Additional Services in the amount and on the terms and conditions set forth herein. Such compensation shall be the obligation of each User. For the purposes of and in accordance with
Section 23.3 (“Users’ Liability for Payments”) of the Master Agreement, these Additional Services shall be considered by all Users to be services performed prior to any effective date of termination. Accordingly and
notwithstanding any other provisions to the contrary in the Master Agreement or any exhibit attached thereto, in the event any amounts owed pursuant to this SOW remain outstanding upon any termination or expiration of the Master Agreement or this
SOW, such amounts shall be immediately due and payable by the charged User(s) as provided for herein. 

  
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 CONFIDENTIAL 

							
	Statement of Work No. 24 Revision 6 (NE)
	SOW: 	 		 	 	 	No
		 		 	ü  	 	Yes

  

	 	8.2	Amendment to Master Agreement - CCT Pricing 

 Pricing under this SOW is set forth Attachment A hereto, which amends Schedule 1 (Service Element Fees/Unit Pricing) under Exhibit E (Pricing Schedules) of the Master Agreement by adding the two Service
Elements under Category 2 as set forth in Attachment A. 
  

	 	8.3	Invoicing and Payment 

 Contractor shall
prepare invoices (separate from Master Agreement invoicing, but which may include invoicing for other SOW charges) on the last day of a calendar month and send to each User for the amount of its User Charges. All invoices shall be due and payable
within thirty (30) days after the date of the invoice. 
  

	 	8.4	Collection and Remedies 

 Collections and
remedies hereunder with respect to a User shall be subject the User’s applicable NPAC/SMS User Agreement. Any billing disputes shall be promptly presented to Contractor in reasonable detail, in writing. Any requests for adjustment shall not be
cause for delay in payment of the undisputed balance due. 
  

	 	8.5	Late Fee 

 Late payments will be subject
to a 1.25% interest charge per month, or, if lower, the maximum rate permitted by law. 
  

	 	8.6	Taxes 

 Each Allocated Payor is to remit
to or reimburse Contractor for any taxes that an Allocated Payor is obligated to pay by law, rule or regulation, or under the Master Agreement, this SOW, or its respective NPAC/SMS User Agreement. 

 

	 	8.7	No Withholding 

 Users may withhold
payment of any amounts which are subject to a bona fide dispute; provided it shall pay all undisputed amounts owing to Contractor that have been separately invoiced to such User. If re-invoice occurs following the thirty (30) day payment
schedule, such invoice for the undisputed amount shall be paid within ten (10) business days of receipt by User. User and Contractor shall seek to resolve any such disputes expeditiously, but in any event within thirty (30) days after
receipt of notice thereof. All disputed amounts ultimately paid or awarded to Contractor shall bear interest from the thirtieth (30th) day following the original invoice. 

  
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 CONFIDENTIAL 

							
	Statement of Work No. 24 Revision 6 (NE)
	SOW: 	 		 	 	 	No
		 		 	ü  	 	Yes

  

 Notwithstanding the foregoing, User may not withhold payment of any amounts invoiced by Contractor based
solely upon a dispute concerning how a User, as an Allocated Payor, is allocated charges under the Allocation Model (as those terms are defined in the Master Agreement). 

 

	9.	MISCELLANEOUS 

 9.1 Except as specifically
modified and amended hereby, all the provisions of the Master Agreement and the User Agreements entered into with respect thereto, and all exhibits and schedules thereto, shall remain unaltered and in full force and effect in accordance with their
terms. From and after the SOW Revision Effective Date hereof, any reference in the Master Agreement to itself and any Article, Section or subsections thereof or to any Exhibit thereto, or in any User Agreement to itself or to the Master Agreement
and applicable to any time from and after the SOW Revision Effective Date hereof, shall be deemed to be a reference to such agreement, Article, Section, subsection or Exhibit, as modified and amended by this SOW. From and after the SOW Revision
Effective Date, the SOW shall be a part of the Master Agreement, including its Exhibits, and, as such, shall be subject to the terms and conditions therein. Each of the respective Master Agreements with respect to separate Service Areas remains an
independent agreement regarding the rights and obligations of each of the Parties thereto with respect to such Service Area, and neither this SOW nor any other instrument shall join or merge any Master Agreement with any other, except by the express
written agreement of the Parties thereto. 
 9.2 If any provision of this SOW is held invalid or unenforceable the remaining provision of this
SOW shall become null and void and be of no further force or effect. If by rule, regulation, order, opinion or decision of the Federal Communications Commission or any other regulatory body having jurisdiction or delegated authority with respect to
the subject matter of this SOW or the Master Agreement, this SOW is required to be rescinded or is declared ineffective or void in whole or in part, whether temporarily, permanently or ab initio (an “Ineffectiveness
Determination”), immediately upon such Ineffectiveness Determination and without any requirement on any party to appeal, protest or otherwise seek clarification of such Ineffectiveness Determination, this SOW shall be rescinded and
of no further force or effect retroactively to the SOW Revision Effective Date. Consequently, the Master Agreement in effect immediately prior to the SOW Revision Effective Date shall continue in full force and effect in accordance with its terms,
unchanged or modified in any way by this SOW. In the event of an Ineffectiveness Determination, any amounts that would have otherwise been due and payable under the terms and conditions of the Master Agreement, in effect immediately prior to the SOW
Revision Effective Date (including, but not limited to any adjustments necessary to retroactively re-price TN Porting Events under Exhibit E from the SOW Revision Effective Date through the date of the Ineffectiveness Determination, or other amounts
or credits, to any party hereunder), shall be invoiced by Contractor at the earliest practical Billing Cycle in accordance with the Master Agreement and shall be due and payable in accordance with the applicable invoice therewith or shall be
credited or applied for the benefit of the Customer or any Allocated Payor in accordance with the Master Agreement. 

  
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 CONFIDENTIAL 

							
	Statement of Work No. 24 Revision 6 (NE)
	SOW: 	 		 	 	 	No
		 		 	ü  	 	Yes

  

 9.3. This SOW Revision may be executed in two or more counterparts and by different parties hereto in
separate counterparts, with the same effect as if all parties had signed the same document. All such counterparts shall be deemed an original, shall be construed together and shall constitute one and the same instrument. 

9.4 If at any time hereafter a customer, other than a Subscribing Customer that is a party hereto, desires to become a party hereto, then such customer
may become a party hereto by executing a joinder agreement under which it agrees to be bound by the terms and conditions of this SOW, as modified from time to time. 
 9.5 This SOW is the joint work product of representatives of Customer and Contractor; accordingly, in the event of ambiguities, no inferences will be drawn against either party, including the party that
drafted the Agreement in its final form. 
 9.6 This SOW sets forth the entire understanding between the Parties with regard to the subject
matter hereof and supersedes any prior or contemporaneous agreement, discussions, negotiations or representations between the Parties, whether written or oral, with respect thereto. The modifications, amendments and price concessions made herein
were negotiated together and collectively, and each is made in consideration of all of the other terms herein. All such modifications, amendments and price concessions are interrelated and are dependent on each other. No separate, additional or
different consideration is contemplated with respect to the modifications, amendments and price concessions herein. 
 [THIS
SPACE INTENTIONALLY LEFT BLANK] 

  
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 CONFIDENTIAL 

							
	Statement of Work No. 24 Revision 6 (NE)
	SOW: 	 		 	 	 	No
		 		 	ü  	 	Yes

  

 IN WITNESS WHEREOF, the undersigned have executed this Statement of Work: 

 

			
	CONTRACTOR: NeuStar, Inc.
		
	By:	 	 /s/ Bradley D. Smith

	Its:	 	 Controller

	Date:	 	 9-17-12

	
	CUSTOMER: North American Portability Management LLC, as successor in interest to and on behalf of Northeast Carrier Acquisition Company, LLC
		
	By:	 	 /s/ Melvin Clay

	Its:	 	 NAPM LLC Co-Chair

	Date:	 	 9/6/2012

		
	By:	 	 /s/ Timothy Decker

	Its:	 	 NAPM LLC CO-CHAIR

	Date:	 	 9/7/2012

  
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 CONFIDENTIAL 

							
	Statement of Work No. 24 Revision 6 (NE)
	SOW: 	 		 	 	 	No
		 		 	ü  	 	Yes

  

 ATTACHMENT A 

TO 

STATEMENT OF WORK NO. 24, REVISION 6 
 Amendment to Schedule 1, Category 2, of Exhibit E 
  

							
	 Category
	  	 Service Element
	  	 Unit
	  	 Price

				
		  	Bulk Data Download provided to User with suspended association during the Initial Suspension period.	  	BDD per NPAC Service Area provided during Initial Suspension period (one per day per applicable NPAC Service Area must be accepted).	  	No charge for one BDD in each NPAC region per day.
				
		  	Bulk Data Download provided to User with suspended association during the Continued Suspension period.	  	BDD per NPAC Service Area provided during Continued Suspension period (one per day per applicable NPAC Service Area must be accepted), as provided by SOW 24, as
revised.	  	$500 for each NPAC region BDD.

  
 Page 11

 CONFIDENTIALFifth Amendment to Lease, dated September 19, 2012

 Exhibit 10.1 
 FIFTH AMENDMENT TO LEASE 
  

			
	PARTIES:	  	RGH HOLDINGS LIMITED PARTNERSHIP, an Alaskan limited partnership (successor-in-interest to E.G. SIRRAH LLC, a California limited liability company)
		  	P.O. Box 2790
		  	Malibu, California 90265
		  	(“Lessor”)
		
		  	ACADIA PHARMACEUTICALS INC., a Delaware corporation
		  	3911 Sorrento Valley Boulevard
		  	San Diego, California 92121
		  	(“Lessee”)
		
	DATE:	  	September 19, 2012
		
	PLACE:	  	Los Angeles, California

  
  

RECITALS 
 A. Lessor and Lessee are the current parties to a Lease dated August 15, 1997 between R.G. Harris Co. and Harris Family Revocable Trust, as Lessor, and Receptor Technology, Inc. (the “Original
Lease”), as amended by an Amendment No. 1 dated October 30, 1997 (the “First Amendment”), by an Amendment No. 2 dated November 1, 2005 (the “Second Amendment”), by a Third Amendment to Lease dated
November 30, 2007 (the “Third Amendment”), and by a Fourth Amendment to Lease re Termination of Lease as to 3931 Sorrento dated January 22, 2010 (the “Fourth Amendment”) (collectively, the “Lease”), pertaining
to premises located at 3911 Sorrento Valley Boulevard, San Diego, California (the “Premises”). 
 B. The term of the
Lease is presently scheduled to expire on December 31, 2012. However, the parties wish to extend the term of the Lease through June 30, 2013, and month-to-month thereafter unless and until either party terminates the Lease by written
notice to the other party, on the terms and conditions as further described in this Fifth Amendment to Lease (the “Fifth Amendment”). 

  
 1 

 THEREFORE, Lessor and Lessee hereby amend the Lease in the following particulars only, with
all other terms and conditions of the Lease to remain the same: 
 AGREEMENT 

1. Extension of Term. The Original Term, as defined in Paragraph 1.3 of the Original Lease, and as extended by the Second
Amendment and the Third Amendment, is hereby further extended by at least six (6) months, so that it shall continue at least through June 30, 2013, and shall continue on a month-to-month basis thereafter. Either party may terminate such
month-to-month tenancy by giving at least thirty (30) days’ prior written notice of such termination to the other party, which notice shall set out the effective date of such termination; provided, however, that no such termination shall
be effective earlier than June 30, 2013. Such date of termination set out in a termination notice shall be the new “Expiration Date” as described in such Paragraph 1.3 of the Original Lease (also sometimes referred to as the
“Termination Date” in the Second Amendment and the Third Amendment). All of Lessee’s extension options, early termination rights, expansion rights, and first refusal rights have previously expired and are deemed deleted from the
Lease. 
 2. Base Rent for Original Premises. Effective January 1, 2013, the monthly Base Rent (on a
“triple-net” basis) to be paid by Lessee to Lessor for the Premises shall be as follows: 
  

					
	 Period of Time
	  	Monthly
Base Rent	 
		
	 1/1/2013-6/30/2013
	  	$	26,916.00	  

 After June 30, 2013, the monthly Base Rent to be paid by Lessee to Lessor for the Premises shall
remain $26,916.00 per month. 
 The Base Rents set forth in this Paragraph 2 for the period from and after January 1, 2013,
are in addition to, not in lieu of, the charges described in the Lease other than Base Rent. Such other charges for which Lessee shall remain liable include, but are not limited to, Lessee’s obligations for Real Property Taxes, insurance
premiums, utility costs and other operating expenses of the Premises and the Project as required by the Lease, as amended to date (including but not limited to Section 5 of the Fourth Amendment). The Base Rent (and all other periodic charges
for which Lessee is liable under the Lease) shall be equitably prorated, as calculated by Lessor in its reasonable discretion, for any partial calendar month (and any partial calendar year) in which the Expiration Date occurs, based upon the number
of days during such calendar month (and calendar year) that Lessee leased the Premises up through the Expiration Date. 
 3.
Lessee’s Exit Assessment and Surrender upon Termination. Without limiting Lessor’s rights under Paragraphs 6 and 7 of the Original Lease or other provisions of the Lease, as amended to date, Lessee, at Lessee’s sole cost and
expense, shall cause to be conducted on or before the Expiration Date, a preliminary environmental site assessment by Occupational Services, Inc. of San Diego, California (or another qualified consultant

  
 2 

 
pre-approved in writing by Lessor) with respect to the existence of Hazardous Substances (as defined in Paragraph 6 of the Original Lease) on or about the Premises, and shall promptly provide to
Lessor a copy of such consultant's written report. Lessee’s obligations regarding Hazardous Substances as set forth in Paragraph 6.2 of the Original Lease shall survive the expiration or termination of the Lease. 

Upon the expiration or termination of the Lease, Lessee shall surrender the Premises in the manner and condition required by Paragraph
7.4 of the Original Lease and other applicable lease provisions, free of any occupancies, claims to occupancy, liens, Trade Fixtures (as defined in Paragraph 7.3(a) of the Original Lease) or personal property of Lessee or of any subtenant or other
third party claiming under Lessee. The parties agree that Lessor shall be required to make the written election described in Paragraph 7.4(b) of the Original Lease (electing to require Lessee’s removal of certain “Lessee Owned Alterations
or Utility Installations” from the Premises (the “Removal Election”)) at any time after the date of this Fifth Amendment up until thirty (30) days after the Expiration Date, as amended by Paragraph 1 above. Provided, however,
that if Lessor makes a Removal Election, then Lessee shall complete such removal and related work prior to the latter of (i) the date thirty (30) days after Lessor gives written notice to Lessee of such election, or (ii) the
Expiration Date. 
 4. No Brokerage Commissions. The parties acknowledge that no brokers represent either party in this
transaction. If Lessee has dealt with any real estate broker or other person or firm with respect to this Fifth Amendment, Lessee shall be solely responsible for the payment of any fee due such broker, person or firm, and Lessee hereby agrees to
indemnify, defend and hold Lessor harmless from and against any claim, liability or expense with respect thereto. Similarly, if Lessor has dealt with any real estate broker or other person or firm with respect to this Fifth Amendment, Lessor shall
be solely responsible for the payment of any fee due such broker, person or firm, and Lessor hereby agrees to indemnify, defend and hold Lessee harmless from and against any claim, liability or expense with respect thereto. Except as provided above
in this Paragraph 4, Lessor shall not be responsible for any compensation to any brokers for their services rendered in this transaction. 
 5. Lessor’s Marketing of Premises. Lessee agrees that from and after the parties’ full execution and delivery of this Fifth Amendment (and irrespective of whether or not Lessor and Lessee
are engaged in negotiations for a potential new lease or lease extension), Lessor shall have the right to actively market the Premises for lease or sale to third parties, and, starting January 1, 2013, (i) to place “For Sale”
and/or “For Lease” signs on or about the Premises, and (ii) to show the Premises to such third parties and their guests and advisors, either directly or through real estate brokers or salespersons. Lessee shall cooperate in providing
to Lessor reasonable access to the Premises for such showings at reasonable times upon reasonable telephonic notice. (Lessor’s provision of at least one business days’ advance notice for a showing between 9 a.m. and 5 p.m.,

  
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Monday through Friday, except holidays, shall be deemed reasonable for this purpose.) The provisions of this Paragraph 5 shall not limit any other rights of access Lessor may have under the
Lease, including but not limited to Paragraph 32 of the Original Lease, but the provisions in such Paragraph 32 limiting showings to prospective lessees and the posting of “For Lease” signs to the last six months of the Lease term shall no
longer apply. 
 6. Confidentiality. Lessee agrees to hold in confidence the economic terms of this Fifth Amendment and
agrees not to disclose such terms to any third party; provided, however, that Lessee may disclose such terms (a) to Lessee’s agents, employees, professional advisors, and lenders who require such information in the course of their duties
for or financial dealings with Lessee, so long as Lessee advises such persons and entities in writing of the provisions of this Paragraph 6 and causes them to hold such information in confidence; (b) as required to comply with applicable local,
state or federal laws, including the rules and regulations of the Securities and Exchange Commission; and (c) as necessary to enforce the provisions of the Lease, as amended by this Fifth Amendment. 

7. Miscellaneous. This Fifth Amendment supersedes all prior or contemporaneous understandings, negotiations, or agreements between
the parties, whether written or oral, with respect to its subject matter. This Fifth Amendment is part of and shall be attached as an addendum to the Lease. The Lease, as amended by this Fifth Amendment, may be further amended only in a writing
signed by both Lessor and Lessee. All terms of the Lease which have not been expressly altered by this Fifth Amendment shall remain in full force and effect. In the event of any litigation or other proceeding between the parties arising out of or
relating to this Fifth Amendment, the recovery of reasonable attorney fees and costs of suit shall be governed by the terms of Paragraph 31 of the Original Lease. 
 8. Execution in Counterparts; Electronic Signatures. This Fifth Amendment to Lease may be executed in counterparts by the parties, and when each party has signed and delivered at least one such
counterpart, each counterpart shall be deemed an original, and, when taken together with other signed counterparts, shall constitute one agreement, which shall be binding upon and effective as to both parties. Each party shall be bound by signatures
transmitted by facsimile or e-mail in the same fashion as such party would be bound by original signatures. Any party delivering signatures by facsimile or e-mail transmission shall, for convenience and record-keeping purposes, provide original
signatures to the other parties within 10 days after such party binds itself by facsimile or e-mail signatures. 

  
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 IN WITNESS WHEREOF, the parties have executed this Fifth Amendment to Lease as of the date
and at the place first written above. 
  

							
	LESSEE:	 		 	ACADIA PHARMACEUTICALS INC., a Delaware corporation
				
		 		 	By:	 	 /s/ Thomas H. Aasen

		 		 	Name:	 	Thomas H. Aasen
		 		 	Title:	 	Executive Vice President
			
	LESSOR:	 		 	RGH HOLDINGS LIMITED PARTNERSHIP, an Alaskan limited partnership
				
		 		 	By:	 	 /s/ Henry K. Workman, Jr.

		 		 	Name:	 	Henry K. Workman, Jr.
		 		 	Title:	 	General Partner

  
 5

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