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                                                                    EXHIBIT 10.1

                           SYNTA PHARMACEUTICALS CORP.

                                 2001 STOCK PLAN
                      (AS AMENDED AND RESTATED ON 5/09/05)

1.       DEFINITIONS.

         Unless otherwise specified or unless the context otherwise
         requires, the following terms, as used in this Synta Pharmaceuticals
         Corp. 2001 Stock Plan, have the following meanings:

                  ADMINISTRATOR means the Board of Directors, unless it
                  has delegated power to act on its behalf to the Committee, in
                  which case the Administrator means the Committee.

                  AFFILIATE means a corporation which, for purposes of
                  Section 424 of the Code, is a parent or subsidiary of the
                  Company, direct or indirect.

                  BOARD OF DIRECTORS means the Board of Directors of the
                  Company.

                  CHANGE OF CONTROL means the occurrence of any of the following
                  events:

                           (i) Ownership. Any "Person" (as such term is
                           used in Sections 13(d) and 14(d) of the Securities
                           Exchange Act of 1934, as amended) becomes the
                           "Beneficial Owner" (as defined in Rule 13d-3 under
                           said Act), directly or indirectly, of securities of
                           the Company representing 50% or more of the total
                           voting power represented by the Company's then
                           outstanding voting securities (excluding for this
                           purpose any such voting securities held by the
                           Company or its Affiliates or by any employee benefit
                           plan of the Company) pursuant to a transaction or a
                           series of related transactions which the Board of
                           Directors does not approve; or

                           (ii) Merger/Sale of Assets. (A) A merger or
                           consolidation of the Company whether or not approved
                           by the Board of Directors, other than a merger or
                           consolidation which would result in the voting
                           securities of the Company outstanding immediately
                           prior thereto continuing to represent (either by
                           remaining outstanding or by being converted into
                           voting securities of the surviving entity or the
                           parent of such corporation) at least 50% of the total
                           voting power represented by the voting securities of
                           the Company or such surviving entity or parent of
                           such corporation, as the case may be,

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                           outstanding immediately after such merger or
                           consolidation; (B) or the stockholders of the Company
                           approve an agreement for the sale or disposition by
                           the Company of all or substantially all of the
                           Company's assets; or

                           (iii) Change in Board Composition. A change in the
                           composition of the Board of Directors, as a
                           result of which fewer than a majority of the
                           directors are Incumbent Directors. "Incumbent
                           Directors" shall mean directors who either (A) are
                           directors of the Company as of January 11, 2005, or
                           (B) are elected, or nominated for election, to the
                           Board of Directors with the affirmative votes of at
                           least a majority of the Incumbent Directors at the
                           time of such election or nomination (but shall not
                           include an individual whose election or nomination is
                           in connection with an actual or threatened proxy
                           contest relating to the election of directors to the
                           Company).

                  CODE means the United States Internal Revenue Code of 1986,
                  as amended.

                  COMMITTEE means the committee of the Board of Directors to
                  which the Board of Directors has delegated power to act under
                  or pursuant to the provisions of the Plan.

                  COMMON STOCK means shares of the Company's common stock,
                  $.0001 par value per share.

                  COMPANY means Synta Pharmaceuticals Corp., a Delaware
                  corporation.

                  DISABILITY or DISABLED means permanent and total disability as
                  defined in Section 22(e)(3) of the Code.

                  FAIR MARKET VALUE of a Share of Common Stock means:

                  (1) If the Common Stock is listed on a national securities
                  exchange or traded in the over-the-counter market and sales
                  prices are regularly reported for the Common Stock, the
                  closing or last price of the Common Stock on the composite
                  tape or other comparable reporting system for the trading day
                  immediately preceding the applicable date;

                  (2) If the Common Stock is not traded on a national securities
                  exchange but is traded on the over-the-counter market, if
                  sales prices are not regularly reported for the Common Stock
                  for the trading day referred to in clause (1), and if bid and
                  asked prices for the Common Stock are regularly reported, the
                  mean between the bid and the asked price for the Common Stock
                  at the close of trading in the over-the-counter market for the
                  trading day on which Common Stock was traded immediately
                  preceding the applicable date; and

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                  (3) If the Common Stock is neither listed on a national
                  securities exchange nor traded in the over-the-counter market,
                  such value as the Administrator, in good faith, shall
                  determine.

                  ISO means an option meant to qualify as an incentive stock
                  option under Section 422 of the Code.

                  KEY EMPLOYEE means an employee of the Company or of an
                  Affiliate (including, without limitation, an employee who is
                  also serving as an officer or director of the Company or of an
                  Affiliate), designated by the Administrator to be eligible to
                  be granted one or more Stock Rights under the Plan.

                  NON-QUALIFIED OPTION means an option which is not intended to
                  qualify as an ISO.

                  OPTION means an ISO or Non-Qualified Option granted under the
                  Plan.

                  OPTION AGREEMENT means an agreement between the Company and a
                  Participant delivered pursuant to the Plan, in such form as
                  the Administrator shall approve.

                  PARTICIPANT means a Key Employee, director or consultant to
                  whom one or more Stock Rights are granted under the Plan. As
                  used herein, "Participant" shall include "Participant's
                  Survivors" where the context requires.

                  PLAN means this Synta Pharmaceuticals Corp. 2001 Stock Plan.

                  SHARES means shares of the Common Stock as to which Stock
                  Rights have been or may be granted under the Plan or any
                  shares of capital stock into which the Shares are changed or
                  for which they are exchanged within the provisions of
                  Paragraph 3 of the Plan. The Shares issued under the Plan may
                  be authorized and unissued shares or shares held by the
                  Company in its treasury, or both.

                  STOCK GRANT means a grant by the Company of Shares under the
                  Plan.

                  STOCK GRANT AGREEMENT means an agreement between the Company
                  and a Participant delivered pursuant to the Plan, in such form
                  as the Administrator shall approve.

                  STOCK RIGHT means a right to Shares of the Company granted
                  pursuant to the Plan -- an ISO, a Non-Qualified Option or a
                  Stock Grant.

                  SURVIVORS means a deceased Participant's legal representatives
                  or any person or persons who acquired the Participant's rights
                  to a Stock Right by will or by the laws of descent and
                  distribution.

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2.       PURPOSES OF THE PLAN.

         The Plan is intended to encourage ownership of Shares by Key Employees
and directors of and certain consultants to the Company in order to attract such
people, to induce them to work for the benefit of the Company or of an Affiliate
and to provide additional incentive for them to promote the success of the
Company or of an Affiliate. The Plan provides for the granting of ISOs,
Non-Qualified Options and Stock Grants.

3.       SHARES SUBJECT TO THE PLAN.

         The number of Shares which may be issued from time to time pursuant to
this Plan shall be 15,000,000, or the equivalent of such number of Shares after
the Administrator, in its sole discretion, has interpreted the effect of any
stock split, stock dividend, combination, recapitalization or similar
transaction in accordance with Paragraph 23 of the Plan.

         If an Option ceases to be outstanding, in whole or in part, or if the
Company shall reacquire any Shares issued pursuant to a Stock Grant, the Shares
which were subject to such Option and any Shares so reacquired by the Company
shall be available for the granting of other Stock Rights under the Plan. Any
Option shall be treated as outstanding until such Option is exercised in full,
or terminates or expires under the provisions of the Plan, or by agreement of
the parties to the pertinent Option Agreement.

4.       ADMINISTRATION OF THE PLAN.

         The Administrator of the Plan will be the Board of Directors, except to
the extent the Board of Directors delegates its authority to the Committee, in
which case the Committee shall be the Administrator. Subject to the provisions
of the Plan, the Administrator is authorized to:

         a. Interpret the provisions of the Plan or of any Option or Stock Grant
            and to make all rules and determinations which it deems necessary or
            advisable for the administration of the Plan;

         b. Determine which employees of the Company or of an Affiliate shall be
            designated as Key Employees and which of the Key Employees,
            directors and consultants shall be granted Stock Rights; and

         c. Determine the number of Shares for which Stock Rights shall be
            granted.

         d. Specify the terms and conditions upon which Stock Rights may be
            granted;

provided, however, that all such interpretations, rules, determinations, terms
and conditions shall be made and prescribed in the context of preserving the tax
status under Section 422 of the Code of those Options which are designated as
ISOs. Subject to the foregoing, the interpretation and construction by the
Administrator of any provisions of the Plan or of any Stock Right granted

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under it shall be final, unless otherwise determined by the Board of Directors,
if the Administrator is the Committee.

5.       ELIGIBILITY FOR PARTICIPATION.

         The Administrator will, in its sole discretion, name the Participants
in the Plan, provided, however, that each Participant must be a Key Employee,
director or consultant of the Company or of an Affiliate at the time a Stock
Right is granted. Notwithstanding the foregoing, the Administrator may authorize
the grant of a Stock Right to a person not then an employee, director or
consultant of the Company or of an Affiliate; provided, however, that the actual
grant of such Stock Right shall be conditioned upon such person becoming
eligible to become a Participant at or prior to the time of the delivery of the
Agreement evidencing such Stock Right. ISOs may be granted only to Key
Employees. Non-Qualified Options and Stock Grants may be granted to any Key
Employee, director or consultant of the Company or an Affiliate. The granting of
any Stock Right to any individual shall neither entitle that individual to, nor
disqualify him or her from, participation in any other grant of Stock Rights.

6.       TERMS AND CONDITIONS OF OPTIONS.

         Each Option shall be set forth in writing in an Option Agreement, duly
executed by the Company and, to the extent required by law or requested by the
Company, by the Participant. The Administrator may provide that Options be
granted subject to such terms and conditions, consistent with the terms and
conditions specifically required under this Plan, as the Administrator may deem
appropriate including, without limitation, subsequent approval by the
shareholders of the Company of this Plan or any amendments thereto.

         A. NON-QUALIFIED OPTIONS: Each Option intended to be a Non-Qualified
            Option shall be subject to the terms and conditions which the
            Administrator determines to be appropriate and in the best interest
            of the Company, subject to the following minimum standards for any
            such Non-Qualified Option:

            a. OPTION PRICE: Each Option Agreement shall state the option price
               (per share) of the Shares covered by each Option, which option
               price shall be determined by the Administrator but shall not be
               less than the par value per share of Common Stock.

            b. NUMBER OF SHARES: Each Option Agreement shall state the number of
               Shares to which it pertains.

            c. OPTION PERIODS: Each Option Agreement shall state the date or
               dates on which it first is exercisable and the date after which
               it may no longer be exercised, and may provide that the Option
               rights accrue or become exercisable in installments over a period
               of months or years, or upon the

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               the occurrence of certain conditions or the attainment of stated
               goals or events.

            d. OPTION CONDITIONS: Exercise of any Option may be conditioned upon
               the Participant's execution of a Share purchase agreement in form
               satisfactory to the Administrator providing for certain
               protections for the Company and its other shareholders, including
               requirements that:

               i.   The Participant's or the Participant's Survivors' right to
                    sell or transfer the Shares may be restricted; and

               ii.  The Participant or the Participant's Survivors may be
                    required to execute letters of investment intent and must
                    also acknowledge that the Shares will bear legends noting
                    any applicable restrictions.

            e. DIRECTORS' OPTIONS. Each director of the Company who is not an
               employee of the Company or any Affiliate, upon first being
               elected or appointed to the Board of Directors, and upon every
               fourth anniversary thereof provided that on such dates such
               director has been in the continued and uninterrupted service as a
               director of the Company or the Affiliate since his or her
               election or appointment and is a director and is not an employee
               or consultant of the Company or the Affiliate at such time, may,
               within the discretion of the Board of Directors, be granted a
               Non-Qualified Option to purchase such number of shares as
               determined by the Board of Directors. Such Option may be granted
               to a director on such date as he or she was appointed to be a
               director, and upon every fourth anniversary thereof provided that
               on such date such director has been in the continued and
               uninterrupted service as a director of the Company or the
               Affiliate since his or her initial appointment as a director, and
               is a director and is not an employee or consultant of the Company
               or the Affiliate at such time. Each such Option shall (i) have an
               exercise price equal to the Fair Market Value (per share) of the
               Shares on the date of grant of the Option, (ii) have a term of
               ten (10) years, and (iii) provided that the grantee of the Option
               still serves as a director of the Company or the Affiliate,
               become cumulatively exercisable as follows: 25% upon the first
               anniversary of the date of the grant of the Option, and 6.25%
               upon the expiration of each successive quarter thereafter. Any
               director entitled to receive an Option grant under this
               subparagraph may elect to decline the Option.

Except as otherwise provided in the pertinent Option Agreement, if a director
who receives Options pursuant to this subparagraph:

            a. ceases to be a member of the Board of Directors for any reason
               other than death or Disability, any unexercised Options granted
               to such director may be exercised by the director within a period
               of ninety (90) days after the date the director ceases to be a
               member of the Board of Directors, but only to the extent of the
               number of Shares with respect to which the Options are
               exercisable on the date the director ceases to be a member

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               of the Board of Directors, and in no event later than the
               expiration date of the Option; or

            b. ceases to be a member of the Board of Directors by reason of his
               or her death or Disability, any unexercised Options granted to
               such director may be exercised by the director (or by the
               director's personal representative, or the director's Survivors)
               within a period of one hundred eighty (180) days after the date
               the director ceases to be a member of the Board of Directors, but
               only to the extent of the number of Shares with respect to which
               the Options are exercisable on the date the director ceases to be
               a member of the Board of Directors, and in no event later than
               the expiration date of the Option.

         B. ISOS: Each Option intended to be an ISO shall be issued only to a
            Key Employee and be subject to the following terms and conditions,
            with such additional restrictions or changes as the Administrator
            determines are appropriate but not in conflict with Section 422 of
            the Code and relevant regulations and rulings of the Internal
            Revenue Service:

            a. MINIMUM STANDARDS: The ISO shall meet the minimum standards
               required of Non-Qualified Options, as described in Paragraph 6(A)
               above, except clauses (a) and (e) thereunder.

            b. OPTION PRICE: Immediately before the Option is granted, if the
               Participant owns, directly or by reason of the applicable
               attribution rules in Section 424(d) of the Code:

               i.   Ten percent (10%) OR LESS of the total combined voting power
                    of all classes of stock of the Company or an Affiliate, the
                    Option price per share of the Shares covered by each Option
                    shall not be less than one hundred percent (100%) of the
                    Fair Market Value per share of the Shares on the date of the
                    grant of the Option.

               ii.  More than ten percent (10%) of the total combined voting
                    power of all classes of stock of the Company or an
                    Affiliate, the Option price per share of the Shares covered
                    by each Option shall not be less than one hundred ten
                    percent (110%) of the said Fair Market Value on the date of
                    grant.

            c. TERM OF OPTION: For Participants who own

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               i.   Ten percent (10%) OR LESS of the total combined voting power
                    of all classes of stock of the Company or an Affiliate, each
                    Option shall terminate not more than ten (10) years from the
                    date of the grant or at such earlier time as the Option
                    Agreement may provide.

               ii.  More than ten percent (10%) of the total combined voting
                    power of all classes of stock of the Company or an
                    Affiliate, each Option shall terminate not more than five
                    (5) years from the date of the grant or at such earlier time
                    as the Option Agreement may provide.

            d. LIMITATION ON YEARLY EXERCISE: The Option Agreements shall
               restrict the amount of Options which may be exercisable in any
               calendar year (under this or any other ISO plan of the Company or
               an Affiliate) so that the aggregate Fair Market Value (determined
               at the time each ISO is granted) of the stock with respect to
               which ISOs are exercisable for the first time by the Participant
               in any calendar year does not exceed one hundred thousand dollars
               ($100,000), provided that this subparagraph (d) shall have no
               force or effect if its inclusion in the Plan is not necessary for
               Options issued as ISOs to qualify as ISOs pursuant to Section
               422(d) of the Code.

7.       TERMS AND CONDITIONS OF STOCK GRANTS.

         Each offer of a Stock Grant to a Participant shall state the date prior
to which the Stock Grant must be accepted by the Participant, and the principal
terms of each Stock Grant shall be set forth in a Stock Grant Agreement, duly
executed by the Company and, to the extent required by law or requested by the
Company, by the Participant. The Stock Grant Agreement shall be in a form
approved by the Administrator and shall contain terms and conditions which the
Administrator determines to be appropriate and in the best interest of the
Company, subject to the following minimum standards:

         (a) Each Stock Grant Agreement shall state the purchase price (per
             share), if any, of the Shares covered by each Stock Grant, which
             purchase price shall be determined by the Administrator but shall
             not be less than the minimum consideration required by the Delaware
             General Corporation Law on the date of the grant of the Stock
             Grant;

         (b) Each Stock Grant Agreement shall state the number of Shares to
             which the Stock Grant pertains; and

         (c) Each Stock Grant Agreement shall include the terms of any right of
             the Company to reacquire the Shares subject to the Stock Grant,
             including the time and events upon which such rights shall accrue
             and the purchase price therefor, if any.

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8.       EXERCISE OF OPTIONS AND ISSUE OF SHARES.

         An Option (or any part or installment thereof) shall be exercised by
giving written notice to the Company at its principal executive office address,
together with provision for payment of the full purchase price in accordance
with this Paragraph for the Shares as to which the Option is being exercised,
and upon compliance with any other condition(s) set forth in the Option
Agreement. Such written notice shall be signed by the person exercising the
Option, shall state the number of Shares with respect to which the Option is
being exercised and shall contain any representation required by the Plan or the
Option Agreement. Payment of the purchase price for the Shares as to which such
Option is being exercised shall be made (a) in United States dollars in cash or
by check, or (b) at the discretion of the Administrator, through delivery of
shares of Common Stock having a Fair Market Value equal as of the date of the
exercise to the cash exercise price of the Option, or (c) at the discretion of
the Administrator, by having the Company retain from the shares otherwise
issuable upon exercise of the Option, a number of shares having a Fair Market
Value equal as of the date of exercise to the exercise price of the Option, or
(d) at the discretion of the Administrator, by delivery of the grantee's
personal recourse note bearing interest payable not less than annually at no
less than 100% of the applicable Federal rate, as defined in Section 1274(d) of
the Code, or (e) at the discretion of the Administrator, in accordance with a
cashless exercise program established with a securities brokerage firm, and
approved by the Administrator, or (f) at the discretion of the Administrator, by
any combination of (a), (b), (c), (d) and (e) above. Notwithstanding the
foregoing, the Administrator shall accept only such payment on exercise of an
ISO as is permitted by Section 422 of the Code.

         The Company shall then reasonably promptly deliver the Shares as to
which such Option was exercised to the Participant (or to the Participant's
Survivors, as the case may be). In determining what constitutes "reasonably
promptly," it is expressly understood that the issuance and delivery of the
Shares may be delayed by the Company in order to comply with any law or
regulation (including, without limitation, state securities or "blue sky" laws)
which requires the Company to take any action with respect to the Shares prior
to their issuance. The Shares shall, upon delivery, be evidenced by an
appropriate certificate or certificates for fully paid, non-assessable Shares.

         The Administrator shall have the right to accelerate the date of
exercise of any installment of any Option; provided that the Administrator shall
not accelerate the exercise date of any installment of any Option granted to any
Key Employee as an ISO (and not previously converted into a Non-Qualified Option
pursuant to Paragraph 26) if such acceleration would violate the annual vesting
limitation contained in Section 422(d) of the Code, as described in Paragraph
6.B.d.

         The Administrator may, in its discretion, amend any term or condition
of an outstanding Option provided (i) such term or condition as amended is
permitted by the Plan, (ii) any such amendment shall be made only with the
consent of the Participant to whom the Option was granted, or in the event of
the death of the Participant, the Participant's Survivors, if the amendment is
adverse to the Participant, and (iii) any such amendment of any ISO shall be
made only after the Administrator, after consulting the counsel for the Company,
determines whether such amendment would constitute a modification (as that term
is defined in Section 424(h) of the

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Code) of any Option which is an ISO or would cause any adverse tax consequences
for the holder of such ISO.

9.       ACCEPTANCE OF STOCK GRANT AND ISSUE OF SHARES.

         A Stock Grant (or any part or installment thereof) shall be accepted by
executing the Stock Grant Agreement and delivering it to the Company at its
principal office address, together with provision for payment of the full
purchase price, if any, in accordance with this Paragraph for the Shares as to
which such Stock Grant is being accepted, and upon compliance with any other
conditions set forth in the Stock Grant Agreement. Payment of the purchase price
for the Shares as to which such Stock Grant is being accepted shall be made (a)
in United States dollars in cash or by check, or (b) at the discretion of the
Administrator, through delivery of shares of Common Stock having a fair market
value equal as of the date of acceptance of the Stock Grant to the purchase
price of the Stock Grant determined in good faith by the Administrator, or (c)
at the discretion of the Administrator, by delivery of the grantee's personal
recourse note bearing interest payable not less than annually at no less than
100% of the applicable Federal rate, as defined in Section 1274(d) of the Code,
or (d) at the discretion of the Administrator, by any combination of (a), (b)
and (c) above.

         The Company shall then reasonably promptly deliver the Shares as to
which such Stock Grant was accepted to the Participant (or to the Participant's
Survivors, as the case may be), subject to any escrow provision set forth in the
Stock Grant Agreement. In determining what constitutes "reasonably promptly," it
is expressly understood that the issuance and delivery of the Shares may be
delayed by the Company in order to comply with any law or regulation (including,
without limitation, state securities or "blue sky" laws) which requires the
Company to take any action with respect to the Shares prior to their issuance.

         The Administrator may, in its discretion, amend any term or condition
of an outstanding Stock Grant or Stock Grant Agreement provided (i) such term or
condition as amended is permitted by the Plan, and (ii) any such amendment shall
be made only with the consent of the Participant to whom the Stock Grant was
made, if the amendment is adverse to the Participant.

10.      RIGHTS AS A SHAREHOLDER.

         No Participant to whom a Stock Right has been granted shall have rights
as a shareholder with respect to any Shares covered by such Stock Right, except
after due exercise of the Option or acceptance of the Stock Grant and tender of
the full purchase price, if any, for the Shares being purchased pursuant to such
exercise or acceptance and registration of the Shares in the Company's share
register in the name of the Participant.

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11.      ASSIGNABILITY AND TRANSFERABILITY OF STOCK RIGHTS.

         By its terms, a Stock Right granted to a Participant shall not be
transferable by the Participant other than (i) by will or by the laws of descent
and distribution, or (ii) as otherwise determined by the Administrator and set
forth in the applicable Option Agreement or Stock Grant Agreement. The
designation of a beneficiary of a Stock Right by a Participant, with the prior
approval of the Administrator and in such form as the Administrator shall
prescribe, shall not be deemed a transfer prohibited by this Paragraph. Except
as provided above, a Stock Right shall only be exercisable or may only be
accepted, during the Participant's lifetime, by such Participant (or by his or
her legal representative) and shall not be assigned, pledged or hypothecated in
any way (whether by operation of law or otherwise) and shall not be subject to
execution, attachment or similar process. Any attempted transfer, assignment,
pledge, hypothecation or other disposition of any Stock Right or of any rights
granted thereunder contrary to the provisions of this Plan, or the levy of any
attachment or similar process upon a Stock Right, shall be null and void.

12.      EFFECT ON OPTIONS OF TERMINATION OF SERVICE OTHER THAN "FOR CAUSE" OR
         DEATH OR DISABILITY.

         Except as otherwise provided in the pertinent Option Agreement in the
event of a termination of service (whether as an employee, director or
consultant) with the Company or an Affiliate before the Participant has
exercised an Option, the following rules apply:

         a. A Participant who ceases to be an employee, director or consultant
            of the Company or of an Affiliate (for any reason other than
            termination "for cause", Disability, or death for which events there
            are special rules in Paragraphs 13, 14, and 15, respectively), may
            exercise any Option granted to him or her to the extent that the
            Option is exercisable on the date of such termination of service,
            but only within such term as the Administrator has designated in the
            pertinent Option Agreement.

         b. Except as provided in Subparagraph (c) below, or Paragraph 14 or 15,
            in no event may an Option Agreement provide, if an Option is
            intended to be an ISO, that the time for exercise be later than
            three (3) months after the Participant's termination of employment.

         c. The provisions of this Paragraph, and not the provisions of
            Paragraph 14 or 15, shall apply to a Participant who subsequently
            becomes Disabled or dies after the termination of employment,
            director status or consultancy, provided, however, in the case of a
            Participant's Disability or death within three (3) months after the
            termination of employment, director status or consultancy, the
            Participant or the Participant's Survivors may exercise the Option
            within one (1) year after the date of the Participant's termination
            of employment, but in no event after the date of expiration of the
            term of the Option.

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         d. Notwithstanding anything herein to the contrary, if subsequent to a
            Participant's termination of employment, termination of director
            status or termination of consultancy, but prior to the exercise of
            an Option, the Board of Directors determines that, either prior or
            subsequent to the Participant's termination, the Participant engaged
            in conduct which would constitute "cause", then such Participant
            shall forthwith cease to have any right to exercise any Option.

         e. A Participant to whom an Option has been granted under the Plan who
            is absent from work with the Company or with an Affiliate because of
            temporary disability (any disability other than a Disability as
            defined in Paragraph 1 hereof), or who is on leave of absence for
            any purpose, shall not, during the period of any such absence, be
            deemed, by virtue of such absence alone, to have terminated such
            Participant's employment, director status or consultancy with the
            Company or with an Affiliate, except as the Administrator may
            otherwise expressly provide.

         f. Except as required by law or as set forth in the pertinent Option
            Agreement, Options granted under the Plan shall not be affected by
            any change of a Participant's status within or among the Company and
            any Affiliates, so long as the Participant continues to be an
            employee, director or consultant of the Company or any Affiliate.

13.      EFFECT ON OPTIONS OF TERMINATION OF SERVICE "FOR CAUSE".

         Except as otherwise provided in the pertinent Option Agreement, the
following rules apply if the Participant's service (whether as an employee,
director or consultant) with the Company or an Affiliate is terminated "for
cause" prior to the time that all his or her outstanding Options have been
exercised:

         a. All outstanding and unexercised Options as of the time the
            Participant is notified his or her service is terminated "for cause"
            will immediately be forfeited.

         b. For purposes of this Plan, "cause" shall include (and is not limited
            to) dishonesty with respect to the Company or any Affiliate,
            insubordination, substantial malfeasance or non-feasance of duty,
            unauthorized disclosure of confidential information, and conduct
            substantially prejudicial to the business of the Company or any
            Affiliate. The determination of the Administrator as to the
            existence of "cause" will be conclusive on the Participant and the
            Company.

         c. "Cause" is not limited to events which have occurred prior to a
            Participant's termination of service, nor is it necessary that the
            Administrator's finding of "cause" occur prior to termination. If
            the Administrator determines, subsequent to a Participant's
            termination of service but prior to the exercise of an Option, that
            either prior or subsequent to the Participant's termination the
            Participant engaged in conduct which would constitute "cause", then
            the right to exercise any Option is forfeited.

                                       12
<Page>

         d. Any definition in an agreement between the Participant and the
            Company or an Affiliate, which contains a conflicting definition of
            "cause" for termination and which is in effect at the time of such
            termination, shall supersede the definition in this Plan with
            respect to such Participant.

14.      EFFECT ON OPTIONS OF TERMINATION OF SERVICE FOR DISABILITY.

         Except as otherwise provided in the pertinent Option Agreement, a
Participant who ceases to be an employee, director or consultant of the Company
or of an Affiliate by reason of Disability may exercise any Option granted to
such Participant:

         a. To the extent exercisable but not exercised on the date of
            Disability; and

         b. In the event rights to exercise the Option accrue periodically, to
            the extent of a pro rata portion of any additional rights as would
            have accrued had the Participant not become Disabled prior to the
            end of the accrual period which next ends following the date of
            Disability. The proration shall be based upon the number of days of
            such accrual period prior to the date of Disability.

         A Disabled Participant may exercise such rights only within the period
ending one (1) year after the date of the Participant's termination of
employment, directorship or consultancy, as the case may be, notwithstanding
that the Participant might have been able to exercise the Option as to some or
all of the Shares on a later date if the Participant had not become Disabled and
had continued to be an employee, director or consultant or, if earlier, within
the originally prescribed term of the Option.

         The Administrator shall make the determination both of whether
Disability has occurred and the date of its occurrence (unless a procedure for
such determination is set forth in another agreement between the Company and
such Participant, in which case such procedure shall be used for such
determination). If requested, the Participant shall be examined by a physician
selected or approved by the Administrator, the cost of which examination shall
be paid for by the Company.

15.      EFFECT ON OPTIONS OF DEATH WHILE AN EMPLOYEE, DIRECTOR OR CONSULTANT.

         Except as otherwise provided in the pertinent Option Agreement, in the
event of the death of a Participant while the Participant is an employee,
director or consultant of the Company or of an Affiliate, such Option may be
exercised by the Participant's Survivors:

         a. To the extent exercisable but not exercised on the date of death;
            and

                                       13
<Page>

         b. In the event rights to exercise the Option accrue periodically, to
            the extent of a pro rata portion of any additional rights which
            would have accrued had the Participant not died prior to the end of
            the accrual period which next ends following the date of death. The
            proration shall be based upon the number of days of such accrual
            period prior to the Participant's death.

         If the Participant's Survivors wish to exercise the Option, they must
take all necessary steps to exercise the Option within one (1) year after the
date of death of such Participant, notwithstanding that the decedent might have
been able to exercise the Option as to some or all of the Shares on a later date
if he or she had not died and had continued to be an employee, director or
consultant or, if earlier, within the originally prescribed term of the Option.

16.      EFFECT OF TERMINATION OF SERVICE ON STOCK GRANTS.

         In the event of a termination of service (whether as an employee,
director or consultant) with the Company or an Affiliate for any reason before
the Participant has accepted a Stock Grant, such offer shall terminate.

         For purposes of this Paragraph 16 and Paragraph 17 below, a Participant
to whom a Stock Grant has been offered under the Plan who is absent from work
with the Company or with an Affiliate because of temporary disability (any
disability other than a permanent and total Disability as defined in Paragraph 1
hereof), or who is on leave of absence for any purpose, shall not, during the
period of any such absence, be deemed, by virtue of such absence alone, to have
terminated such Participant's employment, director status or consultancy with
the Company or with an Affiliate, except as the Administrator may otherwise
expressly provide.

         In addition, for purposes of this Paragraph 16 and Paragraph 17 below,
any change of employment or other service within or among the Company and any
Affiliates shall not be treated as a termination of employment, director status
or consultancy so long as the Participant continues to be an employee, director
or consultant of the Company or any Affiliate.

17.      EFFECT ON STOCK GRANTS OF TERMINATION OF SERVICE OTHER THAN "FOR CAUSE"
         OR DEATH OR DISABILITY.

         Except as otherwise provided in the pertinent Stock Grant Agreement, in
the event of a termination of service (whether as an employee, director or
consultant), other than termination "for cause," Disability, or death for which
events there are special rules in Paragraphs 18, 19, and 20, respectively,
before all Company rights of repurchase shall have lapsed, then the Company
shall have the right to repurchase that number of Shares subject to a Stock
Grant as to which the Company's repurchase rights have not lapsed.

                                       14
<Page>

18.      EFFECT ON STOCK GRANTS OF TERMINATION OF SERVICE "FOR CAUSE".

         Except as otherwise provided in the pertinent Stock Grant Agreement,
the following rules apply if the Participant's service (whether as an employee,
director or consultant) with the Company or an Affiliate is terminated "for
cause":

         a. All Shares subject to any Stock Grant shall be immediately subject
            to repurchase by the Company at the purchase price, if any, thereof.

         b. For purposes of this Plan, "cause" shall include (and is not limited
            to) dishonesty with respect to the employer, insubordination,
            substantial malfeasance or non-feasance of duty, unauthorized
            disclosure of confidential information, and conduct substantially
            prejudicial to the business of the Company or any Affiliate. The
            determination of the Administrator as to the existence of "cause"
            will be conclusive on the Participant and the Company.

         c. "Cause" is not limited to events which have occurred prior to a
            Participant's termination of service, nor is it necessary that the
            Administrator's finding of "cause" occur prior to termination. If
            the Administrator determines, subsequent to a Participant's
            termination of service, that either prior or subsequent to the
            Participant's termination the Participant engaged in conduct which
            would constitute "cause," then the Company's right to repurchase all
            of such Participant's Shares shall apply.

         d. Any definition in an agreement between the Participant and the
            Company or an Affiliate, which contains a conflicting definition of
            "cause" for termination and which is in effect at the time of such
            termination, shall supersede the definition in this Plan with
            respect to such Participant.

19.      EFFECT ON STOCK GRANTS OF TERMINATION OF SERVICE FOR DISABILITY.

         Except as otherwise provided in the pertinent Stock Grant Agreement,
the following rules apply if a Participant ceases to be an employee, director or
consultant of the Company or of an Affiliate by reason of Disability: to the
extent the Company's rights of repurchase have not lapsed on the date of
Disability, they shall be exercisable; provided, however, that in the event such
rights of repurchase lapse periodically, such rights shall lapse to the extent
of a pro rata portion of the Shares subject to such Stock Grant as would have
lapsed had the Participant not become Disabled prior to the end of the vesting
period which next ends following the date of Disability. The proration shall be
based upon the number of days of such vesting period prior to the date of
Disability.

         The Administrator shall make the determination both of whether
Disability has occurred and the date of its occurrence (unless a procedure for
such determination is set forth in another agreement between the Company and
such Participant, in which case such procedure shall be

                                       15
<Page>

used for such determination). If requested, the Participant shall be examined by
a physician selected or approved by the Administrator, the cost of which
examination shall be paid for by the Company.

20.      EFFECT ON STOCK GRANTS OF DEATH WHILE AN EMPLOYEE, DIRECTOR OR
         CONSULTANT.

         Except as otherwise provided in the pertinent Stock Grant Agreement,
the following rules apply in the event of the death of a Participant while the
Participant is an employee, director or consultant of the Company or of an
Affiliate: to the extent the Company's rights of repurchase have not lapsed on
the date of death, they shall be exercisable; provided, however, that in the
event such rights of repurchase lapse periodically, such rights shall lapse to
the extent of a pro rata portion of the Shares subject to such Stock Grant as
would have lapsed had the Participant not died prior to the end of the vesting
period which next ends following the date of death. The proration shall be based
upon the number of days of such vesting period prior to the Participant's death.

21.      PURCHASE FOR INVESTMENT.

         Unless the offering and sale of the Shares to be issued upon the
particular exercise or acceptance of a Stock Right shall have been effectively
registered under the Securities Act of 1933, as now in force or hereafter
amended (the "1933 Act"), the Company shall be under no obligation to issue the
Shares covered by such exercise unless and until the following conditions have
been fulfilled:

         a. The person(s) who exercise(s) or accept(s) such Stock Right shall
            warrant to the Company, prior to the receipt of such Shares, that
            such person(s) are acquiring such Shares for their own respective
            accounts, for investment, and not with a view to, or for sale in
            connection with, the distribution of any such Shares, in which event
            the person(s) acquiring such Shares shall be bound by the provisions
            of the following legend which shall be endorsed upon the
            certificate(s) evidencing their Shares issued pursuant to such
            exercise or such grant:

                 "The shares represented by this certificate have been taken for
                 investment and they may not be sold or otherwise transferred by
                 any person, including a pledgee, unless (1) either (a) a
                 Registration Statement with respect to such shares shall be
                 effective under the Securities Act of 1933, as amended, or (b)
                 the Company shall have received an opinion of counsel
                 satisfactory to it that an exemption from registration under
                 such Act is then available, and (2) there shall have been
                 compliance with all applicable state securities laws."

                                       16
<Page>

         b. At the discretion of the Administrator, the Company shall have
            received an opinion of its counsel that the Shares may be issued
            upon such particular exercise or acceptance in compliance with the
            1933 Act without registration thereunder.

22.      DISSOLUTION OR LIQUIDATION OF THE COMPANY.

         Upon the dissolution or liquidation of the Company, all Options granted
under this Plan which as of such date shall not have been exercised and all
Stock Grants which have not been accepted will terminate and become null and
void; provided, however, that if the rights of a Participant or a Participant's
Survivors have not otherwise terminated and expired, the Participant or the
Participant's Survivors will have the right immediately prior to such
dissolution or liquidation to exercise or accept any Stock Right to the extent
that the Stock Right is exercisable or subject to acceptance as of the date
immediately prior to such dissolution or liquidation.

23.      ADJUSTMENTS.

         Upon the occurrence of any of the following events, a Participant's
rights with respect to any Stock Right granted to him or her hereunder shall be
adjusted as hereinafter provided, unless otherwise specifically provided in the
pertinent Option Agreement or Stock Grant Agreement:

         A. STOCK DIVIDENDS AND STOCK SPLITS. If (i) the shares of Common Stock
shall be subdivided or combined into a greater or smaller number of shares or if
the Company shall issue any shares of Common Stock as a stock dividend on its
outstanding Common Stock, or (ii) additional shares or new or different shares
or other securities of the Company or other non-cash assets are distributed with
respect to such shares of Common Stock, the number of shares of Common Stock
deliverable upon the exercise or acceptance of such Stock Right may be
appropriately increased or decreased proportionately, and appropriate
adjustments may be made in the purchase price per share to reflect such events.

         B. CONSOLIDATIONS OR MERGERS. If the Company is to be consolidated with
or acquired by another entity in a merger, sale of all or substantially all of
the Company's assets other than a transaction to merely change the state of
incorporation (a "Corporate Transaction"), the Administrator or the board of
directors of any entity assuming the obligations of the Company hereunder (the
"Successor Board"), shall, as to outstanding Options, either (i) make
appropriate provision for the continuation of such Options by substituting on an
equitable basis for the Shares then subject to such Options either the
consideration payable with respect to the outstanding shares of Common Stock in
connection with the Corporate Transaction or securities of any successor or
acquiring entity; or (ii) upon written notice to the Participants, provide that
all Options must be exercised, within a specified number of days of the date of
such notice at the end of which period the Options shall terminate (all Options
shall for purposes of

                                       17
<Page>

this clause (ii) be made fully vested and exercisable immediately prior to their
termination); or (iii) terminate all Options in exchange for a cash payment
equal to the excess of the Fair Market Value of the Shares subject to such
Options over the exercise price thereof (all Options shall for purposes of this
clause (iii) be made fully vested and immediately exercisable immediately prior
to their termination).

         With respect to outstanding Stock Grants, the Administrator or the
Successor Board, shall either (i) make appropriate provisions for the
continuation of such Stock Grants on the same terms and conditions by
substituting on an equitable basis for the Shares then subject to such Stock
Grants either the consideration payable with respect to the outstanding Shares
of Common Stock in connection with the Corporate Transaction or securities of
any successor or acquiring entity; or (ii) terminate all Stock Grants in
exchange for a cash payment equal to the excess of the Fair Market Value of the
Shares (without regard to repurchase rights of the Company) subject to such
Stock Grants over the purchase price thereof, if any.

         The provisions of this Section 23B shall be applicable to all Options
and Stock Grants made under the Plan from the Plan's adoption in 2001.

         C. RECAPITALIZATION OR REORGANIZATION. In the event of a
recapitalization or reorganization of the Company (other than a transaction
described in Subparagraph B above) pursuant to which securities of the Company
or of another corporation are issued with respect to the outstanding shares of
Common Stock, a Participant upon exercising or accepting a Stock Right shall be
entitled to receive for the purchase price, if any, paid upon such exercise or
acceptance the securities which would have been received if such Stock Right had
been exercised or accepted prior to such recapitalization or reorganization.

         D. MODIFICATION OF ISOS. Notwithstanding the foregoing, any adjustments
made pursuant to Subparagraph A, B or C with respect to ISOs shall be made only
after the Administrator, after consulting with counsel for the Company,
determines whether such adjustments would constitute a "modification" of such
ISOs (as that term is defined in Section 424(h) of the Code) or would cause any
adverse tax consequences for the holders of such ISOs. If the Administrator
determines that such adjustments made with respect to ISOs would constitute a
modification of such ISOs, it may refrain from making such adjustments, unless
the holder of an ISO specifically requests in writing that such adjustment be
made and such writing indicates that the holder has full knowledge of the
consequences of such "modification" on his or her income tax treatment with
respect to the ISO.

E.       CHANGE OF CONTROL.  In the event of either

                  (A) a Corporate Transaction that also constitutes a Change of
Control, where outstanding options are assumed or substituted in accordance with
the first paragraph of Subparagraph B clause (i) above and, with respect to
Stock Grants, in accordance with the second paragraph of Subparagraph B clause
(i); or

                  (B) a Change of Control that does not also constitute a
Corporate Transaction,

if within six months after the date of such Change of Control, (i) a
Participant's service is terminated by the Company or an Affiliate for any
reason other than Cause; or (ii) a Participant

                                       18
<Page>

terminates his or her service as a result of being required to change the
principal location where he or she renders services to a location more than 50
miles from his or her location of employment or consultancy immediately prior to
the Change of Control; or (iii) the Participant terminates his or her service
after there occurs a material adverse change in a Participant's duties,
authority or responsibilities which causes such Participant's position with the
Company to become of significantly less responsibility or authority than such
Participant's position was immediately prior to the Change of Control, THEN all
of such Participant's Options outstanding under the Plan shall become fully
vested and immediately exercisable as of the date of termination of such
Participant, unless in any such case an Option has otherwise expired or been
terminated pursuant to its terms or the terms of the Plan and any repurchase
rights of the Company with respect to outstanding Stock Grants that have not
lapsed or expired prior to such Change of Control shall terminate as of the date
of termination of such Participant.

         The provisions of this Section 23E shall be applicable to all Options
and Stock Grants made under the Plan from the Plan's adoption in 2001.

24.      ISSUANCES OF SECURITIES.

         Except as expressly provided herein, no issuance by the Company of
shares of stock of any class, or securities convertible into shares of stock of
any class, shall affect, and no adjustment by reason thereof shall be made with
respect to, the number or price of shares subject to Stock Rights. Except as
expressly provided herein, no adjustments shall be made for dividends paid in
cash or in property (including without limitation, securities) of the Company
prior to any issuance of Shares pursuant to a Stock Right.

25.      FRACTIONAL SHARES.

         No fractional shares shall be issued under the Plan and the person
exercising a Stock Right shall receive from the Company cash in lieu of such
fractional shares equal to the Fair Market Value thereof.

26.      CONVERSION OF ISOS INTO NON-QUALIFIED OPTIONS; TERMINATION OF ISOS.

         The Administrator, at the written request of any Participant, may in
its discretion take such actions as may be necessary to convert such
Participant's ISOs (or any portions thereof) that have not been exercised on the
date of conversion into Non-Qualified Options at any time prior to the
expiration of such ISOs, regardless of whether the Participant is an employee of
the Company or an Affiliate at the time of such conversion. Such actions may
include, but not be limited to, extending the exercise period or reducing the
exercise price of the appropriate installments of such Options. At the time of
such conversion, the Administrator (with the consent of the Participant) may
impose such conditions on the exercise of the resulting Non-Qualified Options as
the Administrator in its discretion may determine, provided that such conditions
shall not be inconsistent with this Plan. Nothing in the Plan shall be deemed to
give

                                       19
<Page>

any Participant the right to have such Participant's ISOs converted into
Non-Qualified Options, and no such conversion shall occur until and unless the
Administrator takes appropriate action. The Administrator, with the consent of
the Participant, may also terminate any portion of any ISO that has not been
exercised at the time of such conversion.

27.      WITHHOLDING.

         In the event that any federal, state, or local income taxes, employment
taxes, Federal Insurance Contributions Act ("F.I.C.A.") withholdings or other
amounts are required by applicable law or governmental regulation to be withheld
from the Participant's salary, wages or other remuneration in connection with
the exercise or acceptance of a Stock Right or in connection with a
Disqualifying Disposition (as defined in Paragraph 28) or upon the lapsing of
any right of repurchase, the Company may withhold from the Participant's
compensation, if any, or may require that the Participant advance in cash to the
Company, or to any Affiliate of the Company which employs or employed the
Participant, the statutory minimum amount of such withholdings unless a
different withholding arrangement, including the use of shares of the Company's
Common Stock or a promissory note, is authorized by the Administrator (and
permitted by law). For purposes hereof, the fair market value of the shares
withheld for purposes of payroll withholding shall be determined in the manner
provided in Paragraph 1 above, as of the most recent practicable date prior to
the date of exercise. If the fair market value of the shares withheld is less
than the amount of payroll withholdings required, the Participant may be
required to advance the difference in cash to the Company or the Affiliate
employer. The Administrator in its discretion may condition the exercise of an
Option for less than the then Fair Market Value on the Participant's payment of
such additional withholding.

28.      NOTICE TO COMPANY OF DISQUALIFYING DISPOSITION.

         Each Key Employee who receives an ISO must agree to notify the Company
in writing immediately after the Key Employee makes a "Disqualifying
Disposition" of any shares acquired pursuant to the exercise of an ISO. A
Disqualifying Disposition is any disposition (including any sale) of such shares
before the later of (a) two years after the date the Key Employee was granted
the ISO, or (b) one year after the date the Key Employee acquired Shares by
exercising the ISO. If the Key Employee has died before such stock is sold,
these holding period requirements do not apply and no Disqualifying Disposition
can occur thereafter.

29.      TERMINATION OF THE PLAN.

         The Plan will terminate on the date which is ten (10) years from the
EARLIER of the date of its adoption and the date of its approval by the
shareholders of the Company. The Plan may be terminated at an earlier date by
vote of the shareholders of the Company; provided, however, that any such
earlier termination shall not affect any Option Agreements or Stock Grant
Agreements executed prior to the effective date of such termination.

                                       20
<Page>

30.      AMENDMENT OF THE PLAN AND AGREEMENTS.

         The Plan may be amended by the shareholders of the Company. The Plan
may also be amended by the Administrator, including, without limitation, to the
extent necessary to qualify any or all outstanding Stock Rights granted under
the Plan or Stock Rights to be granted under the Plan for favorable federal
income tax treatment (including deferral of taxation upon exercise) as may be
afforded incentive stock options under Section 422 of the Code, and to the
extent necessary to qualify the shares issuable upon exercise or acceptance of
any outstanding Stock Rights granted, or Stock Rights to be granted, under the
Plan for listing on any national securities exchange or quotation in any
national automated quotation system of securities dealers. Any amendment
approved by the Administrator which the Administrator determines is of a scope
that requires shareholder approval shall be subject to obtaining such
shareholder approval. Any modification or amendment of the Plan shall not,
without the consent of a Participant, adversely affect his or her rights under a
Stock Right previously granted to him or her. With the consent of the
Participant affected, the Administrator may amend outstanding Option Agreements
and Stock Grant Agreements in a manner which may be adverse to the Participant
but which is not inconsistent with the Plan. In the discretion of the
Administrator, outstanding Option Agreements and Stock Grant Agreements may be
amended by the Administrator in a manner which is not adverse to the
Participant.

31.      EMPLOYMENT OR OTHER RELATIONSHIP.

         Nothing in this Plan or any Option Agreement or Stock Grant Agreement
shall be deemed to prevent the Company or an Affiliate from terminating the
employment, consultancy or director status of a Participant, nor to prevent a
Participant from terminating his or her own employment, consultancy or director
status or to give any Participant a right to be retained in employment or other
service by the Company or any Affiliate for any period of time.

32.      GOVERNING LAW.

         This Plan shall be construed and enforced in accordance with the law of
the State of Delaware.<Page>

                                                                    EXHIBIT 10.2

                           SYNTA PHARMACEUTICALS CORP.

                                 2006 STOCK PLAN

1.       DEFINITIONS.

         Unless otherwise specified or unless the context otherwise requires,
         the following terms, as used in this Synta Pharmaceuticals Corp. 2006
         Stock Plan, have the following meanings:

                  ADMINISTRATOR means the Board of Directors, unless it has
                  delegated power to act on its behalf to the Committee, in
                  which case the Administrator means the Committee.

                  AFFILIATE means a corporation which, for purposes of Section
                  424 of the Code, is a parent or subsidiary of the Company,
                  direct or indirect.

                  AGREEMENT means an agreement between the Company and a
                  Participant delivered pursuant to the Plan, in such form as
                  the Administrator shall approve.

                  BOARD OF DIRECTORS means the Board of Directors of the
                  Company.

                  CHANGE OF CONTROL means the occurrence of any of the following
                  events:

                           (i)   Ownership. Any "Person" (as such term is used
                                 in Sections 13(d) and 14(d) of the Securities
                                 Exchange Act of 1934, as amended) becomes the
                                 "Beneficial Owner" (as defined in Rule 13d-3
                                 under said Act), directly or indirectly, of
                                 securities of the Company representing 50% or
                                 more of the total voting power represented by
                                 the Company's then outstanding voting
                                 securities (excluding for this purpose any such
                                 voting securities held by the Company or its
                                 Affiliates or by any employee benefit plan of
                                 the Company) pursuant to a transaction or a
                                 series of related transactions which the Board
                                 of Directors does not approve; or

                           (ii)  Merger/Sale of Assets. (A) A merger or
                                 consolidation of the Company whether or not
                                 approved by the Board of Directors, other than
                                 a merger or consolidation which would result in
                                 the voting securities of the Company
                                 outstanding immediately prior thereto
                                 continuing to represent (either by remaining
                                 outstanding or by being converted into voting
                                 securities of the surviving entity or the
                                 parent of such corporation) at least 50% of the
                                 total voting power represented by the voting
                                 securities of the Company or such surviving
                                 entity or parent of such corporation, as the
                                 case may be, outstanding immediately after such
                                 merger or consolidation; (B) or the
                                 stockholders of the Company approve an
                                 agreement for the sale

<Page>

                                 or disposition by the Company of all or
                                 substantially all of the Company's assets; or

                           (iii) Change in Board Composition. A change in the
                                 composition of the Board of Directors, as a
                                 result of which fewer than a majority of the
                                 directors are Incumbent Directors. "Incumbent
                                 Directors" shall mean directors who either (A)
                                 are directors of the Company as of February 15,
                                 2006, or (B) are elected, or nominated for
                                 election, to the Board of Directors with the
                                 affirmative votes of at least a majority of the
                                 Incumbent Directors at the time of such
                                 election or nomination (but shall not include
                                 an individual whose election or nomination is
                                 in connection with an actual or threatened
                                 proxy contest relating to the election of
                                 directors to the Company).

                           CODE means the United States Internal Revenue Code of
                           1986, as amended.

                           COMMITTEE means the committee of the Board of
                           Directors to which the Board of Directors has
                           delegated power to act under or pursuant to the
                           provisions of the Plan.

                           COMMON STOCK means shares of the Company's common
                           stock, $.0001 par value per share.

                           COMPANY means Synta Pharmaceuticals Corp., a Delaware
                           corporation.

                           DISABILITY or DISABLED means permanent and total
                           disability as defined in Section 22(e)(3) of the
                           Code.

                           EMPLOYEE means any employee of the Company or of an
                           Affiliate (including, without limitation, an employee
                           who is also serving as an officer or director of the
                           Company or of an Affiliate), designated by the
                           Administrator to be eligible to be granted one or
                           more Stock Rights under the Plan.

                           FAIR MARKET VALUE of a Share of Common Stock means:

                           (1) If the Common Stock is listed on a national
                           securities exchange or traded in the over-the-counter
                           market and sales prices are regularly reported for
                           the Common Stock, the closing or last price of the
                           Common Stock on the composite tape or other
                           comparable reporting system for the trading day
                           immediately preceding the applicable date;

                           (2) If the Common Stock is not traded on a national
                           securities exchange but is traded on the
                           over-the-counter market, if sales prices are not
                           regularly reported for the Common Stock for the
                           trading day referred to in clause (1), and if bid and
                           asked prices for the Common Stock are regularly
                           reported, the mean between the bid and the asked
                           price for the Common Stock at the close of trading in
                           the over-

                                       2
<Page>

                           the-counter market for the trading day on which
                           Common Stock was traded immediately preceding the
                           applicable date; and

                           (3) If the Common Stock is neither listed on a
                           national securities exchange nor traded in the
                           over-the-counter market, such value as the
                           Administrator, in good faith, shall determine.

                           ISO means an option meant to qualify as an incentive
                           stock option under Section 422 of the Code.

                           NON-QUALIFIED OPTION means an option which is not
                           intended to qualify as an ISO.

                           OPTION means an ISO or Non-Qualified Option granted
                           under the Plan.

                           PARTICIPANT means an Employee, director or consultant
                           of the Company or an Affiliate to whom one or more
                           Stock Rights are granted under the Plan. As used
                           herein, "Participant" shall include "Participant's
                           Survivors" where the context requires.

                           PLAN means this Synta Pharmaceuticals Corp. 2006
                           Stock Plan.

                           SHARES means shares of the Common Stock as to which
                           Stock Rights have been or may be granted under the
                           Plan or any shares of capital stock into which the
                           Shares are changed or for which they are exchanged
                           within the provisions of Paragraph 3 of the Plan. The
                           Shares issued under the Plan may be authorized and
                           unissued shares or shares held by the Company in its
                           treasury, or both.

                           STOCK-BASED AWARD means a grant by the Company under
                           the Plan of an equity award or equity based award
                           which is not an Option or Stock Grant.

                           STOCK GRANT means a grant by the Company of Shares
                           under the Plan.

                           STOCK RIGHT means a right to Shares or the value of
                           Shares of the Company granted pursuant to the Plan --
                           an ISO, a Non-Qualified Option, a Stock Grant or a
                           Stock-Based Award.

                           SURVIVOR means a deceased Participant's legal
                           representatives and/or any person or persons who
                           acquired the Participant's rights to a Stock Right by
                           will or by the laws of descent and distribution.

2.       PURPOSES OF THE PLAN.

         The Plan is intended to encourage ownership of Shares by Employees and
directors of and certain consultants to the Company in order to attract such
people, to induce them to work for the benefit of the Company or of an Affiliate
and to provide additional incentive for them to

                                       3
<Page>

promote the success of the Company or of an Affiliate. The Plan provides for the
granting of ISOs, Non-Qualified Options, Stock Grants and Stock-Based Awards.

3.       SHARES SUBJECT TO THE PLAN.

         (a) The number of Shares which may be issued from time to time pursuant
to this Plan, shall be 9,625,000, or the equivalent of such number of Shares
after the Administrator, in its sole discretion, has interpreted the effect of
any stock split, stock dividend, combination, recapitalization or similar
transaction in accordance with Paragraph 24 of the Plan.

         (b) If an Option ceases to be outstanding, in whole or in part (other
than by exercise), or if the Company shall reacquire (at no more than its
original issuance price) any Shares issued pursuant to a Stock Grant or
Stock-Based Award, or if any Stock Right expires or is forfeited, cancelled, or
otherwise terminated or results in any Shares not being issued, the unissued
Shares which were subject to such Stock Right shall again be available for
issuance from time to time pursuant to this Plan.

         (c) Notwithstanding Subparagraph (a) above, on the first day of each
fiscal year of the Company during the period beginning in fiscal year 2007, and
ending on the second day of fiscal year 2015, the number of Shares that may be
issued from time to time pursuant to the Plan, shall be increased by an amount
equal to the lesser of (i) 5,225,000 or the equivalent of such number of Shares
after the Administrator, in its sole discretion, has interpreted the effect of
any stock split, stock dividend, combination, recapitalization or similar
transaction in accordance with Paragraph 24 of the Plan; (ii) 5% of the number
of outstanding shares of Common Stock on such date; and (iii) an amount
determined by the Board. However, in no event shall the number of Shares
available for issuance under this Plan be increased as set forth in this
Subparagraph (c) to the extent such increase, in addition to any other increases
proposed by the Board in the number of shares of Common Stock available for
issuance under all other employee or director stock plans, including, without
limitation, employee stock purchase plans, would result in the total number of
shares of Common Stock then available for issuance under all employee and
director stock plans exceeding 25% of the outstanding shares of the Company on
the first day of the applicable fiscal year.

         4.       ADMINISTRATION OF THE PLAN.

         The Administrator of the Plan will be the Board of Directors, except to
the extent the Board of Directors delegates its authority to the Committee, in
which case the Committee shall be the Administrator. Subject to the provisions
of the Plan, the Administrator is authorized to:

         a. Interpret the provisions of the Plan and all Stock Rights and to
            make all rules and determinations which it deems necessary or
            advisable for the administration of the Plan;

                                       4
<Page>

         b. Determine which Employees, directors and consultants shall be
            granted Stock Rights;

         c. Determine the number of Shares for which a Stock Right or Stock
            Rights shall be granted; provided, however, that in no event shall
            Stock Rights with respect to more than 500,000 Shares be granted to
            any Participant in any fiscal year;

         d. Specify the terms and conditions upon which a Stock Right or Stock
            Rights may be granted;

         e. to make changes to any outstanding Stock Right, including, without
            limitation, to reduce or increase the exercise price or purchase
            price, to accelerate the vesting schedule or to extend the
            expiration date, provided that no such change shall impair the
            rights of a Participant under any grant previously made without such
            Participant's consent;

         f. to buy out for a payment in cash or Shares, a Stock Right previously
            granted and/or to cancel any such Stock Right and grant in
            substitution therefor other Stock Rights, covering the same or a
            different numbers of Shares and having an exercise price or purchase
            price per share which may be lower or higher than the exercise price
            or purchase price of the cancelled Stock Right, based on such terms
            and conditions as the Administrator shall establish and the
            Participant shall accept; and

         g. Adopt any sub-plans applicable to residents of any specified
            jurisdiction as it deems necessary or appropriate in order to comply
            with or take advantage of any tax or other laws applicable to the
            Company or to Plan Participants or to otherwise facilitate the
            administration of the Plan, which sub-plans may include additional
            restrictions or conditions applicable to Stock Rights or Shares
            issuable pursuant to a Stock Right;

provided, however, that all such interpretations, rules, determinations, terms
and conditions shall be made and prescribed in the context of preserving the tax
status under Section 422 of the Code of those Options which are designated as
ISOs. Subject to the foregoing, the interpretation and construction by the
Administrator of any provisions of the Plan or of any Stock Right granted under
it shall be final, unless otherwise determined by the Board of Directors, if the
Administrator is the Committee. In addition, if the Administrator is the
Committee, the Board of Directors may take any action under the Plan that would
otherwise be the responsibility of the Committee.

         To the extent permitted under applicable law, the Board of Directors or
the Committee may allocate all or any portion of its responsibilities and powers
to any one or more of its members and may delegate all or any portion of its
responsibilities and powers to any other person selected by it. Any such
allocation or delegation may be revoked by the Board of Directors or the
Committee at any time.

                                       5
<Page>

5.       ELIGIBILITY FOR PARTICIPATION.

         The Administrator will, in its sole discretion, name the Participants
in the Plan, provided, however, that each Participant must be an Employee,
director or consultant of the Company or of an Affiliate at the time a Stock
Right is granted. Notwithstanding the foregoing, the Administrator may authorize
the grant of a Stock Right to a person not then an Employee, director or
consultant of the Company or of an Affiliate; provided, however, that the actual
grant of such Stock Right shall be conditioned upon such person becoming
eligible to become a Participant at or prior to the time of the execution of the
Agreement evidencing such Stock Right. ISOs may be granted only to Employees.
Non-Qualified Options, Stock Grants and Stock-Based Awards may be granted to any
Employee, director or consultant of the Company or an Affiliate. The granting of
any Stock Right to any individual shall neither entitle that individual to, nor
disqualify him or her from, participation in any other grant of Stock Rights.

6.       TERMS AND CONDITIONS OF OPTIONS.

         Each Option shall be set forth in writing in an Option Agreement, duly
executed by the Company and, to the extent required by law or requested by the
Company, by the Participant. The Administrator may provide that Options be
granted subject to such terms and conditions, consistent with the terms and
conditions specifically required under this Plan, as the Administrator may deem
appropriate including, without limitation, subsequent approval by the
shareholders of the Company of this Plan or any amendments thereto. The Option
Agreements shall be subject to at least the following terms and conditions:

         A. NON-QUALIFIED OPTIONS: Each Option intended to be a Non-Qualified
            Option shall be subject to the terms and conditions which the
            Administrator determines to be appropriate and in the best interest
            of the Company, subject to the following minimum standards for any
            such Non-Qualified Option:

            a. OPTION PRICE: Each Option Agreement shall state the option price
               (per share) of the Shares covered by each Option, which option
               price shall be determined by the Administrator but shall not be
               less than the Fair Market Value per share of Common Stock.

            b. NUMBER OF SHARES: Each Option Agreement shall state the number of
               Shares to which it pertains.

            c. OPTION PERIODS: Each Option Agreement shall state the date or
               dates on which it first is exercisable and the date after which
               it may no longer be exercised, and may provide that the Option
               rights accrue or become exercisable in installments over a period
               of months or years, or upon the occurrence of certain conditions
               or the attainment of stated goals or events.

                                       6
<Page>

            d. OPTION CONDITIONS: Exercise of any Option may be conditioned upon
               the Participant's execution of a Share purchase agreement in form
               satisfactory to the Administrator providing for certain
               protections for the Company and its other shareholders, including
               requirements that:

               i.   The Participant's or the Participant's Survivors' right to
                    sell or transfer the Shares may be restricted; and

               ii.  The Participant or the Participant's Survivors may be
                    required to execute letters of investment intent and must
                    also acknowledge that the Shares will bear legends noting
                    any applicable restrictions.

         B.  ISOS: Each Option intended to be an ISO shall be issued only to an
             Employee and be subject to the following terms and conditions, with
             such additional restrictions or changes as the Administrator
             determines are appropriate but not in conflict with Section 422 of
             the Code and relevant regulations and rulings of the Internal
             Revenue Service:

            a. MINIMUM STANDARDS: The ISO shall meet the minimum standards
               required of Non-Qualified Options, as described in Paragraph 6(A)
               above, except clause (a) thereunder.

            b. OPTION PRICE: Immediately before the ISO is granted, if the
               Participant owns, directly or by reason of the applicable
               attribution rules in Section 424(d) of the Code:

               i.  Ten percent (10%) OR LESS of the total combined voting power
                   of all classes of stock of the Company or an Affiliate, the
                   Option price per share of the Shares covered by each ISO
                   shall not be less than one hundred percent (100%) of the Fair
                   Market Value per share of the Shares on the date of the grant
                   of the Option; or

               ii. More than ten percent (10%) of the total combined voting
                   power of all classes of stock of the Company or an Affiliate,
                   the Option price per share of the Shares covered by each ISO
                   shall not be less than one hundred ten percent (110%) of the
                   Fair Market Value on the date of grant.

               c.  TERM OF OPTION: For Participants who own:

                    i.  Ten percent (10%) OR LESS of the total combined voting
                        power of all classes of stock of the Company or an
                        Affiliate, each ISO shall terminate not more than ten
                        (10) years from the date of the grant or at such earlier
                        time as the Option Agreement may provide; or

                                       7
<Page>

                    ii. More than ten percent (10%) of the total combined voting
                        power of all classes of stock of the Company or an
                        Affiliate, each ISO shall terminate not more than five
                        (5) years from the date of the grant or at such earlier
                        time as the Option Agreement may provide.

            d. LIMITATION ON YEARLY EXERCISE: The Option Agreements shall
               restrict the amount of ISOs which may become exercisable in any
               calendar year (under this or any other ISO plan of the Company or
               an Affiliate) so that the aggregate Fair Market Value (determined
               at the time each ISO is granted) of the stock with respect to
               which ISOs are exercisable for the first time by the Participant
               in any calendar year does not exceed $100,000.

7.       TERMS AND CONDITIONS OF STOCK GRANTS.

         Each offer of a Stock Grant to a Participant shall state the date prior
to which the Stock Grant must be accepted by the Participant, and the principal
terms of each Stock Grant shall be set forth in an Agreement, duly executed by
the Company and, to the extent required by law or requested by the Company, by
the Participant. The Agreement shall be in a form approved by the Administrator
and shall contain terms and conditions which the Administrator determines to be
appropriate and in the best interest of the Company, subject to the following
minimum standards:

            (a) Each Agreement shall state the purchase price (per share), if
                any, of the Shares covered by each Stock Grant, which purchase
                price shall be determined by the Administrator but shall not be
                less than the minimum consideration required by the Delaware
                General Corporation Law on the date of the grant of the Stock
                Grant;

            (b) Each Agreement shall state the number of Shares to which the
                Stock Grant pertains; and

            (c) Each Agreement shall include the terms of any right of the
                Company to restrict or reacquire the Shares subject to the Stock
                Grant, including the time and events upon which such rights
                shall accrue and the purchase price therefor, if any.

8.       TERMS AND CONDITIONS OF OTHER STOCK-BASED AWARDS.

         The Board shall have the right to grant other Stock-Based Awards based
upon the Common Stock having such terms and conditions as the Board may
determine, including, without limitation, the grant of Shares based upon certain
conditions, the grant of securities convertible into Shares and the grant of
stock appreciation rights, phantom stock awards or stock units. The principal
terms of each Stock-Based Award shall be set forth in an Agreement, duly
executed by the Company and, to the extent required by law or requested by the
Company, by

                                       8
<Page>

the Participant. The Agreement shall be in a form approved by the Administrator
and shall contain terms and conditions which the Administrator determines to be
appropriate and in the best interest of the Company.

9.       EXERCISE OF OPTIONS AND ISSUE OF SHARES.

         An Option (or any part or installment thereof) shall be exercised by
giving written notice to the Company or its designee, together with provision
for payment of the full purchase price in accordance with this Paragraph for the
Shares as to which the Option is being exercised, and upon compliance with any
other condition(s) set forth in the Option Agreement. Such notice shall be
signed by the person exercising the Option, shall state the number of Shares
with respect to which the Option is being exercised and shall contain any
representation required by the Plan or the Option Agreement. Payment of the
purchase price for the Shares as to which such Option is being exercised shall
be made (a) in United States dollars in cash or by check, or (b) at the
discretion of the Administrator, through delivery of shares of Common Stock
having a Fair Market Value equal as of the date of the exercise to the cash
exercise price of the Option, or (c) at the discretion of the Administrator, by
having the Company retain from the shares otherwise issuable upon exercise of
the Option, a number of shares having a Fair Market Value equal as of the date
of exercise to the exercise price of the Option, or (d) at the discretion of the
Administrator, by delivery of the grantee's personal recourse note bearing
interest payable not less than annually at no less than 100% of the applicable
Federal rate, as defined in Section 1274(d) of the Code, or (e) at the
discretion of the Administrator, in accordance with a cashless exercise program
established with a securities brokerage firm, and approved by the Administrator,
or (f) at the discretion of the Administrator, by any combination of (a), (b),
(c), (d) and (e) above, or (g) at the discretion of the Administrator, payment
of such other lawful consideration as the Board may determine. Notwithstanding
the foregoing, the Administrator shall accept only such payment on exercise of
an ISO as is permitted by Section 422 of the Code.

         The Company shall then reasonably promptly deliver the Shares as to
which such Option was exercised to the Participant (or to the Participant's
Survivors, as the case may be). In determining what constitutes "reasonably
promptly," it is expressly understood that the issuance and delivery of the
Shares may be delayed by the Company in order to comply with any law or
regulation (including, without limitation, state securities or "blue sky" laws)
which requires the Company to take any action with respect to the Shares prior
to their issuance. The Shares shall, upon delivery, be fully paid,
non-assessable Shares.

         The Administrator shall have the right to accelerate the date of
exercise of any installment of any Option; provided that the Administrator shall
not accelerate the exercise date of any installment of any Option granted to an
Employee as an ISO (and not previously converted into a Non-Qualified Option
pursuant to Paragraph 27) if such acceleration would violate the annual vesting
limitation contained in Section 422(d) of the Code, as described in Paragraph
6.B.d.

         The Administrator may, in its discretion, amend any term or condition
of an outstanding Option provided (i) such term or condition as amended is
permitted by the Plan, (ii) any such

                                       9
<Page>

amendment shall be made only with the consent of the Participant to whom the
Option was granted, or in the event of the death of the Participant, the
Participant's Survivors, if the amendment is adverse to the Participant, and
(iii) any such amendment of any ISO shall be made only after the Administrator
determines whether such amendment would constitute a "modification" of any
Option which is an ISO (as that term is defined in Section 424(h) of the Code)
or would cause any adverse tax consequences for the holder of such ISO.

10.      ACCEPTANCE OF STOCK GRANTS AND STOCK-BASED AWARDS AND ISSUE OF SHARES.

         A Stock Grant or Stock-Based Award (or any part or installment thereof)
shall be accepted by executing the applicable Agreement and delivering it to the
Company or its designee, together with provision for payment of the full
purchase price, if any, in accordance with this Paragraph for the Shares as to
which such Stock Grant or Stock-Based Award is being accepted, and upon
compliance with any other conditions set forth in the applicable Agreement.
Payment of the purchase price for the Shares as to which such Stock Grant or
Stock-Based Award is being accepted shall be made (a) in United States dollars
in cash or by check, or (b) at the discretion of the Administrator, through
delivery of shares of Common Stock having a Fair Market Value equal as of the
date of acceptance of the Stock Grant or Stock-Based Award to the purchase price
of the Stock Grant or Stock-Based Award, or (c) at the discretion of the
Administrator, by delivery of the grantee's personal recourse note bearing
interest payable not less than annually at no less than 100% of the applicable
Federal rate, as defined in Section 1274(d) of the Code, or (d) at the
discretion of the Administrator, by any combination of (a), (b) and (c) above.

         The Company shall then, if required pursuant to the applicable
Agreement, reasonably promptly deliver the Shares as to which such Stock Grant
or Stock-Based Award was accepted to the Participant (or to the Participant's
Survivors, as the case may be), subject to any escrow provision set forth in the
applicable Agreement. In determining what constitutes "reasonably promptly," it
is expressly understood that the issuance and delivery of the Shares may be
delayed by the Company in order to comply with any law or regulation (including,
without limitation, state securities or "blue sky" laws) which requires the
Company to take any action with respect to the Shares prior to their issuance.

         The Administrator may, in its discretion, amend any term or condition
of an outstanding Stock Grant, Stock-Based Award or applicable Agreement
provided (i) such term or condition as amended is permitted by the Plan, and
(ii) any such amendment shall be made only with the consent of the Participant
to whom the Stock Grant or Stock-Based Award was made, if the amendment is
adverse to the Participant.

11.      RIGHTS AS A SHAREHOLDER.

         No Participant to whom a Stock Right has been granted shall have rights
as a shareholder with respect to any Shares covered by such Stock Right, except
after due exercise of the Option

                                       10

<Page>

or acceptance of the Stock Grant or as set forth in any Agreement and tender of
the full purchase price, if any, for the Shares being purchased pursuant to such
exercise or acceptance and registration of the Shares in the Company's share
register in the name of the Participant.

12.      ASSIGNABILITY AND TRANSFERABILITY OF STOCK RIGHTS.

         By its terms, a Stock Right granted to a Participant shall not be
transferable by the Participant other than (i) by will or by the laws of descent
and distribution, or (ii) as approved by the Administrator in its discretion and
set forth in the applicable Agreement. Notwithstanding the foregoing, an ISO
transferred except in compliance with clause (i) above shall no longer qualify
as an ISO. The designation of a beneficiary of a Stock Right by a Participant,
with the prior approval of the Administrator and in such form as the
Administrator shall prescribe, shall not be deemed a transfer prohibited by this
Paragraph. Except as provided above, a Stock Right shall only be exercisable or
may only be accepted, during the Participant's lifetime, by such Participant (or
by his or her legal representative) and shall not be assigned, pledged or
hypothecated in any way (whether by operation of law or otherwise) and shall not
be subject to execution, attachment or similar process. Any attempted transfer,
assignment, pledge, hypothecation or other disposition of any Stock Right or of
any rights granted thereunder contrary to the provisions of this Plan, or the
levy of any attachment or similar process upon a Stock Right, shall be null and
void.

13.      EFFECT ON OPTIONS OF TERMINATION OF SERVICE OTHER THAN "FOR CAUSE" OR
         DEATH OR DISABILITY.

         Except as otherwise provided in a Participant's Option Agreement in the
event of a termination of service (whether as an employee, director or
consultant) with the Company or an Affiliate before the Participant has
exercised an Option, the following rules apply:

            a. A Participant who ceases to be an employee, director or
               consultant of the Company or of an Affiliate (for any reason
               other than termination "for cause", Disability, or death for
               which events there are special rules in Paragraphs 14, 15, and
               16, respectively), may exercise any Option granted to him or her
               to the extent that the Option is exercisable on the date of such
               termination of service, but only within such term as the
               Administrator has designated in a Participant's Option Agreement.

            b. Except as provided in Subparagraph (c) below, or Paragraph 15 or
               16, in no event may an Option intended to be an ISO, be exercised
               later than three (3) months after the Participant's termination
               of employment.

            c. The provisions of this Paragraph, and not the provisions of
               Paragraph 15 or 16, shall apply to a Participant who subsequently
               becomes Disabled or dies after the termination of employment,
               director status or consultancy; provided, however, in the case of
               a Participant's Disability or death within three (3) months after
               the

                                       11
<Page>

               termination of employment, director status or consultancy, the
               Participant or the Participant's Survivors may exercise the
               Option within one (1) year after the date of the Participant's
               termination of service, but in no event after the date of
               expiration of the term of the Option.

            d. Notwithstanding anything herein to the contrary, if subsequent to
               a Participant's termination of employment, termination of
               director status or termination of consultancy, but prior to the
               exercise of an Option, the Board of Directors determines that,
               either prior or subsequent to the Participant's termination, the
               Participant engaged in conduct which would constitute "cause",
               then such Participant shall forthwith cease to have any right to
               exercise any Option.

            e. A Participant to whom an Option has been granted under the Plan
               who is absent from the Company or an Affiliate because of
               temporary disability (any disability other than a Disability as
               defined in Paragraph 1 hereof), or who is on leave of absence for
               any purpose, shall not, during the period of any such absence, be
               deemed, by virtue of such absence alone, to have terminated such
               Participant's employment, director status or consultancy with the
               Company or with an Affiliate, except as the Administrator may
               otherwise expressly provide.

            f. Except as required by law or as set forth in a Participant's
               Option Agreement, Options granted under the Plan shall not be
               affected by any change of a Participant's status within or among
               the Company and any Affiliates, so long as the Participant
               continues to be an employee, director or consultant of the
               Company or any Affiliate.

14.      EFFECT ON OPTIONS OF TERMINATION OF SERVICE "FOR CAUSE".

         Except as otherwise provided in a Participant's Option Agreement, the
following rules apply if the Participant's service (whether as an employee,
director or consultant) with the Company or an Affiliate is terminated "for
cause" prior to the time that all his or her outstanding Options have been
exercised:

            a. All outstanding and unexercised Options as of the time the
               Participant is notified his or her service is terminated "for
               cause" will immediately be forfeited.

            b. For purposes of this Plan, "cause" shall include (and is not
               limited to) dishonesty with respect to the Company or any
               Affiliate, insubordination, substantial malfeasance or
               non-feasance of duty, unauthorized disclosure of confidential
               information, breach by the Participant of any provision of any
               employment, consulting, advisory, nondisclosure, inventions
               assignment, non-competition or similar agreement between the
               Participant and the Company, and conduct substantially
               prejudicial to the business of the Company or any Affiliate. The
               determination of the Administrator as to the existence of "cause"
               will be conclusive on the Participant and the Company.

                                       12
<Page>

            c. "Cause" is not limited to events which have occurred prior to a
               Participant's termination of service, nor is it necessary that
               the Administrator's finding of "cause" occur prior to
               termination. If the Administrator determines, subsequent to a
               Participant's termination of service but prior to the exercise of
               an Option, that either prior or subsequent to the Participant's
               termination the Participant engaged in conduct which would
               constitute "cause", then the right to exercise any Option is
               forfeited.

            d. Any provision in an agreement between the Participant and the
               Company or an Affiliate, which contains a conflicting definition
               of "cause" for termination and which is in effect at the time of
               such termination, shall supersede the definition in this Plan
               with respect to that Participant.

15.      EFFECT ON OPTIONS OF TERMINATION OF SERVICE FOR DISABILITY.

         Except as otherwise provided in a Participant's Option Agreement, a
Participant who ceases to be an employee, director or consultant of the Company
or of an Affiliate by reason of Disability may exercise any Option granted to
such Participant:

            a. To the extent that the Option has become exercisable but has not
               been exercised on the date of Disability; and

            b. In the event rights to exercise the Option accrue periodically,
               to the extent of a pro rata portion through the date of
               Disability of any additional vesting rights that would have
               accrued on the next vesting date had the Participant not become
               Disabled. The proration shall be based upon the number of days
               accrued in the current vesting period prior to the date of
               Disability.

         A Disabled Participant may exercise such rights only within the period
ending one (1) year after the date of the Participant's termination of
employment, directorship or consultancy, as the case may be, notwithstanding
that the Participant might have been able to exercise the Option as to some or
all of the Shares on a later date if the Participant had not become Disabled and
had continued to be an employee, director or consultant or, if earlier, within
the originally prescribed term of the Option.

         The Administrator shall make the determination both of whether
Disability has occurred and the date of its occurrence (unless a procedure for
such determination is set forth in another agreement between the Company and
such Participant, in which case such procedure shall be used for such
determination). If requested, the Participant shall be examined by a physician
selected or approved by the Administrator, the cost of which examination shall
be paid for by the Company.

                                       13
<Page>

16.      EFFECT ON OPTIONS OF DEATH WHILE AN EMPLOYEE, DIRECTOR OR CONSULTANT.

         Except as otherwise provided in a Participant's Option Agreement, in
the event of the death of a Participant while the Participant is an employee,
director or consultant of the Company or of an Affiliate, such Option may be
exercised by the Participant's Survivors:

            a. To the extent that the Option has become exercisable but has not
               been exercised on the date of death; and

            b. In the event rights to exercise the Option accrue periodically,
               to the extent of a pro rata portion through the date of death of
               any additional vesting rights that would have accrued on the next
               vesting date had the Participant not died. The proration shall be
               based upon the number of days accrued in the current vesting
               period prior to the Participant's date of death.

         If the Participant's Survivors wish to exercise the Option, they must
take all necessary steps to exercise the Option within one (1) year after the
date of death of such Participant, notwithstanding that the decedent might have
been able to exercise the Option as to some or all of the Shares on a later date
if he or she had not died and had continued to be an employee, director or
consultant or, if earlier, within the originally prescribed term of the Option.

17.      EFFECT OF TERMINATION OF SERVICE ON UNACCEPTED STOCK GRANTS.

         In the event of a termination of service (whether as an employee,
director or consultant) with the Company or an Affiliate for any reason before
the Participant has accepted a Stock Grant, such offer shall terminate.

         For purposes of this Paragraph 17 and Paragraph 18 below, a Participant
to whom a Stock Grant has been offered and accepted under the Plan who is absent
from work with the Company or with an Affiliate because of temporary disability
(any disability other than a permanent and total Disability as defined in
Paragraph 1 hereof), or who is on leave of absence for any purpose, shall not,
during the period of any such absence, be deemed, by virtue of such absence
alone, to have terminated such Participant's employment, director status or
consultancy with the Company or with an Affiliate, except as the Administrator
may otherwise expressly provide.

         In addition, for purposes of this Paragraph 17 and Paragraph 18 below,
any change of employment or other service within or among the Company and any
Affiliates shall not be treated as a termination of employment, director status
or consultancy so long as the Participant continues to be an employee, director
or consultant of the Company or any Affiliate.

                                       14
<Page>

18.      EFFECT ON STOCK GRANTS OF TERMINATION OF SERVICE OTHER THAN "FOR
         CAUSE" OR DEATH OR DISABILITY.

         Except as otherwise provided in a Participant's Agreement, in the event
of a termination of service (whether as an employee, director or consultant),
other than termination "for cause," Disability, or death for which events there
are special rules in Paragraphs 19, 20, and 21, respectively, before all Company
rights of repurchase shall have lapsed, then the Company shall have the right to
repurchase that number of Shares subject to a Stock Grant as to which the
Company's repurchase rights have not lapsed.

19.      EFFECT ON STOCK GRANTS OF TERMINATION OF SERVICE "FOR CAUSE".

         Except as otherwise provided in a Participant's Agreement, the
following rules apply if the Participant's service (whether as an employee,
director or consultant) with the Company or an Affiliate is terminated "for
cause":

            a. All Shares subject to any Stock Grant shall be immediately
               subject to repurchase by the Company at the purchase price, if
               any, thereof.

            b. For purposes of this Plan, "cause" shall include (and is not
               limited to) dishonesty with respect to the employer,
               insubordination, substantial malfeasance or non-feasance of duty,
               unauthorized disclosure of confidential information, breach by
               the Participant of any provision of any employment, consulting,
               advisory, nondisclosure, inventions assignment, non-competition
               or similar agreement between the Participant and the Company, and
               conduct substantially prejudicial to the business of the Company
               or any Affiliate. The determination of the Administrator as to
               the existence of "cause" will be conclusive on the Participant
               and the Company.

            c. "Cause" is not limited to events which have occurred prior to a
               Participant's termination of service, nor is it necessary that
               the Administrator's finding of "cause" occur prior to
               termination. If the Administrator determines, subsequent to a
               Participant's termination of service, that either prior or
               subsequent to the Participant's termination the Participant
               engaged in conduct which would constitute "cause," then the
               Company's right to repurchase all of such Participant's Shares
               shall apply.

            d. Any provision in an agreement between the Participant and the
               Company or an Affiliate, which contains a conflicting definition
               of "cause" for termination and which is in effect at the time of
               such termination, shall supersede the definition in this Plan
               with respect to that Participant.

                                       15
<Page>

20.      EFFECT ON STOCK GRANTS OF TERMINATION OF SERVICE FOR DISABILITY.

         Except as otherwise provided in a Participant's Agreement, the
following rules apply if a Participant ceases to be an employee, director or
consultant of the Company or of an Affiliate by reason of Disability: to the
extent the Company's rights of repurchase have not lapsed on the date of
Disability, they shall be exercisable; provided, however, that in the event such
rights of repurchase lapse periodically, such rights shall lapse to the extent
of a pro rata portion of the Shares subject to such Stock Grant through the date
of Disability as would have lapsed had the Participant not become Disabled. The
proration shall be based upon the number of days accrued prior to the date of
Disability.

         The Administrator shall make the determination both of whether
Disability has occurred and the date of its occurrence (unless a procedure for
such determination is set forth in another agreement between the Company and
such Participant, in which case such procedure shall be used for such
determination). If requested, the Participant shall be examined by a physician
selected or approved by the Administrator, the cost of which examination shall
be paid for by the Company.

21.      EFFECT ON STOCK GRANTS OF DEATH WHILE AN EMPLOYEE, DIRECTOR OR
         CONSULTANT.

         Except as otherwise provided in a Participant's Agreement, the
following rules apply in the event of the death of a Participant while the
Participant is an employee, director or consultant of the Company or of an
Affiliate: to the extent the Company's rights of repurchase have not lapsed on
the date of death, they shall be exercisable; provided, however, that in the
event such rights of repurchase lapse periodically, such rights shall lapse to
the extent of a pro rata portion of the Shares subject to such Stock Grant
through the date of death as would have lapsed had the Participant not died. The
proration shall be based upon the number of days accrued prior to the
Participant's death.

22.      PURCHASE FOR INVESTMENT.

         Unless the offering and sale of the Shares to be issued upon the
particular exercise or acceptance of a Stock Right shall have been effectively
registered under the Securities Act of 1933, as now in force or hereafter
amended (the "1933 Act"), the Company shall be under no obligation to issue the
Shares covered by such exercise unless and until the following conditions have
been fulfilled:

            a. The person(s) who exercise(s) or accept(s) such Stock Right shall
               warrant to the Company, prior to the receipt of such Shares, that
               such person(s) are acquiring such Shares for their own respective
               accounts, for investment, and not with a view to, or for sale in
               connection with, the distribution of any such Shares, in which
               event the person(s) acquiring such Shares shall be bound by the
               provisions of the

                                       16
<Page>

               following legend which shall be endorsed upon the certificate(s)
               evidencing their Shares issued pursuant to such exercise or such
               grant:

                     "The shares represented by this certificate have been taken
                     for investment and they may not be sold or otherwise
                     transferred by any person, including a pledgee, unless (1)
                     either (a) a Registration Statement with respect to such
                     shares shall be effective under the Securities Act of 1933,
                     as amended, or (b) the Company shall have received an
                     opinion of counsel satisfactory to it that an exemption
                     from registration under such Act is then available, and (2)
                     there shall have been compliance with all applicable state
                     securities laws."

            b. At the discretion of the Administrator, the Company shall have
               received an opinion of its counsel that the Shares may be issued
               upon such particular exercise or acceptance in compliance with
               the 1933 Act without registration thereunder.

23.      DISSOLUTION OR LIQUIDATION OF THE COMPANY.

         Upon the dissolution or liquidation of the Company, all Options granted
under this Plan which as of such date shall not have been exercised and all
Stock Grants and Stock-Based Awards which have not been accepted, will terminate
and become null and void; provided, however, that if the rights of a Participant
or a Participant's Survivors have not otherwise terminated and expired, the
Participant or the Participant's Survivors will have the right immediately prior
to such dissolution or liquidation to exercise or accept any Stock Right to the
extent that the Stock Right is exercisable or subject to acceptance as of the
date immediately prior to such dissolution or liquidation. Upon the dissolution
or liquidation of the Company, any outstanding Stock-Based Awards shall
immediately terminate unless otherwise determined by the Administrator or
specifically provided in the applicable Agreement.

24.      ADJUSTMENTS.

         Upon the occurrence of any of the following events, a Participant's
rights with respect to any Stock Right granted to him or her hereunder shall be
adjusted as hereinafter provided, unless otherwise specifically provided in a
Participant's Agreement:

         A. STOCK DIVIDENDS AND STOCK SPLITS. If (i) the shares of Common Stock
shall be subdivided or combined into a greater or smaller number of shares or if
the Company shall issue any shares of Common Stock as a stock dividend on its
outstanding Common Stock, or (ii) additional shares or new or different shares
or other securities of the Company or other non-cash assets are distributed with
respect to such shares of Common Stock, the number of shares of Common Stock
deliverable upon the exercise of an Option or acceptance of a Stock Grant may be
appropriately increased or decreased proportionately, and appropriate
adjustments may be made including, in the purchase price per share to reflect
such events. The number of Shares

                                       17
<Page>

subject to the limitation in Paragraphs 3(a), 3(c) and 4(c) shall also be
proportionately adjusted upon the occurrence of such events.

         B. CORPORATE TRANSACTIONS. If the Company is to be consolidated with or
acquired by another entity in a merger, sale of all or substantially all of the
Company's assets other than a transaction to merely change the state of
incorporation (a "Corporate Transaction"), the Administrator or the board of
directors of any entity assuming the obligations of the Company hereunder (the
"Successor Board"), shall, as to outstanding Options, either (i) make
appropriate provision for the continuation of such Options by substituting on an
equitable basis for the Shares then subject to such Options either the
consideration payable with respect to the outstanding shares of Common Stock in
connection with the Corporate Transaction or securities of any successor or
acquiring entity; or (ii) upon written notice to the Participants, provide that
all Options must be exercised, within a specified number of days of the date of
such notice at the end of which period the Options shall terminate (all Options
shall for purposes of this clause (ii) be made fully vested and exercisable
immediately prior to their termination); or (iii) terminate all Options in
exchange for a cash payment equal to the excess of the Fair Market Value of the
Shares subject to such Options over the exercise price thereof (all Options
shall for purposes of this clause (iii) be made fully vested and immediately
exercisable immediately prior to their termination).

         With respect to outstanding Stock Grants, the Administrator or the
Successor Board, shall either (i) make appropriate provisions for the
continuation of such Stock Grants on the same terms and conditions by
substituting on an equitable basis for the Shares then subject to such Stock
Grants either the consideration payable with respect to the outstanding
Shares of Common Stock in connection with the Corporate Transaction or
securities of any successor or acquiring entity; or (ii) terminate all Stock
Grants in exchange for a cash payment equal to the excess of the Fair Market
Value of the Shares (without regard to repurchase rights of the Company)
subject to such Stock Grants over the purchase price thereof, if any.

         C. RECAPITALIZATION OR REORGANIZATION. In the event of a
recapitalization or reorganization of the Company, other than a Corporate
Transaction, pursuant to which securities of the Company or of another
corporation are issued with respect to the outstanding shares of Common Stock, a
Participant upon exercising an Option or accepting a Stock Grant after the
recapitalization or reorganization shall be entitled to receive for the purchase
price paid upon such exercise or acceptance the number of replacement securities
which would have been received if such Option had been exercised or Stock Grant
accepted prior to such recapitalization or reorganization.

         D. ADJUSTMENTS TO STOCK-BASED AWARDS. Upon the happening of any of the
events described in Subparagraphs A, B or C above, any outstanding Stock-Based
Award shall be appropriately adjusted to reflect the events described in such
Subparagraphs. The Administrator or the Successor Board shall determine the
specific adjustments to be made under this Paragraph 24 and, subject to
Paragraph 4, its determination shall be conclusive.

         E. MODIFICATION OF ISOS. Notwithstanding the foregoing, any adjustments
made pursuant to Subparagraph A, B or C above with respect to ISOs shall be made
only after the

                                       18
<Page>

Administrator determines whether such adjustments would constitute a
"modification" of such ISOs (as that term is defined in Section 424(h) of the
Code) or would cause any adverse tax consequences for the holders of such ISOs.
If the Administrator determines that such adjustments made with respect to ISOs
would constitute a modification of such ISOs, it may refrain from making such
adjustments, unless the holder of an ISO specifically requests in writing that
such adjustment be made and such writing indicates that the holder has full
knowledge of the consequences of such "modification" on his or her income tax
treatment with respect to the ISO.

         F.  CHANGE OF CONTROL.  In the event of either

                   (A) a Corporate Transaction that also constitutes a Change of
Control, where outstanding options are assumed or substituted in accordance with
the first paragraph of Subparagraph B clause (i) above and, with respect to
Stock Grants, in accordance with the second paragraph of Subparagraph B clause
(i); or

                   (B) a Change of Control that does not also constitute a
Corporate Transaction,

if within six months after the date of such Change of Control, (i) a
Participant's service is terminated by the Company or an Affiliate for any
reason other than Cause; or (ii) a Participant terminates his or her service as
a result of being required to change the principal location where he or she
renders services to a location more than 50 miles from his or her location of
employment or consultancy immediately prior to the Change of Control; or (iii)
the Participant terminates his or her service after there occurs a material
adverse change in a Participant's duties, authority or responsibilities which
causes such Participant's position with the Company to become of significantly
less responsibility or authority than such Participant's position was
immediately prior to the Change of Control, THEN all of such Participant's
Options outstanding under the Plan shall become fully vested and immediately
exercisable as of the date of termination of such Participant, unless in any
such case an Option has otherwise expired or been terminated pursuant to its
terms or the terms of the Plan and any repurchase rights of the Company with
respect to outstanding Stock Grants that have not lapsed or expired prior to
such Change of Control shall terminate as of the date of termination of such
Participant.

25.      ISSUANCES OF SECURITIES.

         Except as expressly provided herein, no issuance by the Company of
shares of stock of any class, or securities convertible into shares of stock of
any class, shall affect, and no adjustment by reason thereof shall be made with
respect to, the number or price of shares subject to Stock Rights. Except as
expressly provided herein, no adjustments shall be made for dividends paid in
cash or in property (including without limitation, securities) of the Company
prior to any issuance of Shares pursuant to a Stock Right.

                                       19
<Page>

26.      FRACTIONAL SHARES.

         No fractional shares shall be issued under the Plan and the person
exercising a Stock Right shall receive from the Company cash in lieu of such
fractional shares equal to the Fair Market Value thereof.

27.      CONVERSION OF ISOS INTO NON-QUALIFIED OPTIONS; TERMINATION OF ISOS.

         The Administrator, at the written request of any Participant, may in
its discretion take such actions as may be necessary to convert such
Participant's ISOs (or any portions thereof) that have not been exercised on the
date of conversion into Non-Qualified Options at any time prior to the
expiration of such ISOs, regardless of whether the Participant is an employee of
the Company or an Affiliate at the time of such conversion. At the time of such
conversion, the Administrator (with the consent of the Participant) may impose
such conditions on the exercise of the resulting Non-Qualified Options as the
Administrator in its discretion may determine, provided that such conditions
shall not be inconsistent with this Plan. Nothing in the Plan shall be deemed to
give any Participant the right to have such Participant's ISOs converted into
Non-Qualified Options, and no such conversion shall occur until and unless the
Administrator takes appropriate action. The Administrator, with the consent of
the Participant, may also terminate any portion of any ISO that has not been
exercised at the time of such conversion.

28.      WITHHOLDING.

         In the event that any federal, state, or local income taxes, employment
taxes, Federal Insurance Contributions Act ("F.I.C.A.") withholdings or other
amounts are required by applicable law or governmental regulation to be withheld
from the Participant's salary, wages or other remuneration in connection with
the exercise or acceptance of a Stock Right or in connection with a
Disqualifying Disposition (as defined in Paragraph 29) or upon the lapsing of
any right of repurchase, the Company may withhold from the Participant's
compensation, if any, or may require that the Participant advance in cash to the
Company, or to any Affiliate of the Company which employs or employed the
Participant, the statutory minimum amount of such withholdings unless a
different withholding arrangement, including the use of shares of the Company's
Common Stock or a promissory note, is authorized by the Administrator (and
permitted by law). For purposes hereof, the fair market value of the shares
withheld for purposes of payroll withholding shall be determined in the manner
provided in Paragraph 1 above, as of the most recent practicable date prior to
the date of exercise. If the fair market value of the shares withheld is less
than the amount of payroll withholdings required, the Participant may be
required to advance the difference in cash to the Company or the Affiliate
employer. The Administrator in its discretion may condition the exercise of an
Option for less than the then Fair Market Value on the Participant's payment of
such additional withholding.

                                       20
<Page>

29.      NOTICE TO COMPANY OF DISQUALIFYING DISPOSITION.

         Each Employee who receives an ISO must agree to notify the Company in
writing immediately after the Employee makes a "Disqualifying Disposition" of
any shares acquired pursuant to the exercise of an ISO. A Disqualifying
Disposition is defined in Section 424(c) of the Code and includes any
disposition (including any sale or gift) of such shares before the later of (a)
two years after the date the Employee was granted the ISO, or (b) one year after
the date the Employee acquired Shares by exercising the ISO, except as otherwise
provided in Section 424(c) of the Code. If the Employee has died before such
stock is sold, these holding period requirements do not apply and no
Disqualifying Disposition can occur thereafter.

30.      TERMINATION OF THE PLAN.

         The Plan will terminate on February 14, 2016 the date which is ten (10)
years from the EARLIER of the date of its adoption by the Board of Directors and
the date of its approval by the shareholders of the Company. The Plan may be
terminated at an earlier date by vote of the shareholders or the Board of
Directors of the Company; provided, however, that any such earlier termination
shall not affect any Agreements executed prior to the effective date of such
termination.

31.      AMENDMENT OF THE PLAN AND AGREEMENTS.

         The Plan may be amended by the shareholders of the Company. The Plan
may also be amended by the Administrator, including, without limitation, to the
extent necessary to qualify any or all outstanding Stock Rights granted under
the Plan or Stock Rights to be granted under the Plan for favorable federal
income tax treatment (including deferral of taxation upon exercise) as may be
afforded incentive stock options under Section 422 of the Code, and to the
extent necessary to qualify the shares issuable upon exercise or acceptance of
any outstanding Stock Rights granted, or Stock Rights to be granted, under the
Plan for listing on any national securities exchange or quotation in any
national automated quotation system of securities dealers. Any amendment
approved by the Administrator which the Administrator determines is of a scope
that requires shareholder approval shall be subject to obtaining such
shareholder approval. Any modification or amendment of the Plan shall not,
without the consent of a Participant, adversely affect his or her rights under a
Stock Right previously granted to him or her. With the consent of the
Participant affected, the Administrator may amend outstanding Agreements in a
manner which may be adverse to the Participant but which is not inconsistent
with the Plan. In the discretion of the Administrator, outstanding Agreements
may be amended by the Administrator in a manner which is not adverse to the
Participant.

32.      EMPLOYMENT OR OTHER RELATIONSHIP.

         Nothing in this Plan or any Agreement shall be deemed to prevent the
Company or an Affiliate from terminating the employment, consultancy or director
status of a Participant, nor to

                                       21
<Page>

prevent a Participant from terminating his or her own employment, consultancy or
director status or to give any Participant a right to be retained in employment
or other service by the Company or any Affiliate for any period of time.

33.      GOVERNING LAW.

         This Plan shall be construed and enforced in accordance with the law of
the State of Delaware.

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