Document:

Form of Option Agreement & Form of Option Grant Notice

 Exhibit 10.2.1 
 CARDIOMEMS, INC. 
 2001 EQUITY
INCENTIVE PLAN 
 STOCK OPTION AGREEMENT 
 (INCENTIVE STOCK OPTION OR NONSTATUTORY STOCK
OPTION) 
 Pursuant to your Stock Option Grant Notice (“Grant Notice”) and this Stock Option Agreement,
CardioMems, Inc. (the “Company”) has granted you an option under its 2001 Equity Incentive Plan (the “Plan”) to purchase the number of shares of the Company’s Common Stock indicated in your Grant Notice at the exercise price
indicated in your Grant Notice. Defined terms not explicitly defined in this Stock Option Agreement but defined in the Plan shall have the same definitions as in the Plan. 
 The details of your option are as follows: 
 1. VESTING. Subject to the limitations contained herein, your option will vest as provided in your Grant Notice, provided that vesting will cease upon the termination of your Continuous Service.

 2. NUMBER OF SHARES AND EXERCISE
PRICE. The number of shares of Common Stock subject to your option and your exercise price per share referenced in your Grant Notice may be adjusted from time to time for Capitalization Adjustments, as provided in
the Plan. 
 3. EXERCISE PRIOR TO VESTING (“EARLY
EXERCISE”). If permitted in your Grant Notice (i.e., the “Exercise Schedule” indicates that “Early Exercise” of your option is permitted) and subject to the provisions of your option, you may elect at any
time that is both (i) during the period of your Continuous Service and (ii) during the term of your option, to exercise all or part of your option, including the nonvested portion of your option; provided, however, that: 
 (a) a partial exercise of your option shall be deemed to cover first vested shares of Common Stock and then the earliest vesting installment of
unvested shares of Common Stock; 
 (b) any shares of Common Stock so purchased from installments that have not vested as of the date
of exercise shall be subject to the purchase option in favor of the Company as described in the Company’s form of Early Exercise Stock Purchase Agreement; and 
 (c) you shall enter into the Company’s form of Early Exercise Stock Purchase Agreement with a vesting schedule that will result in the same vesting as if no early exercise had occurred. 
 4. ISO EXERCISE LIMITATION. 
 (a) The aggregate Fair Market Value of the shares of Common Stock with respect to which you may exercise your option for the first time during any calendar year, when added to the aggregate Fair Market Value of
the shares of Common Stock subject to any other options designated as Incentive Stock Options and granted to you under any stock option plan of the Company or an Affiliate prior to the Date of Grant with respect to which such options are exercisable
for the first time during the same calendar year, shall not exceed $100,000 (the “ISO Exercise Limitation”) unless applicable law requires that your option be exercisable sooner.1 
  

	1	For purposes of this provision, your options designated as Incentive Stock Options shall be taken into account in the order in which they were granted to you, and
the Fair Market Value of shares of Common Stock shall be determined as of the time the option with respect to such shares of Common Stock is granted. If Section 422 of the Code is amended to provide for a different limitation from that set forth in
this provision, the ISO Exercise Limitation shall be deemed amended effective as of the date required or permitted by such amendment to the Code. 

 (b) Notwithstanding the provisions of paragraph 4(a), if the ISO Exercise Limitation would prevent
you from exercising your option as to vested shares, then the ISO Exercise Limitation shall terminate as to such vested shares as such shares vest, and you may exercise your option as to such vested shares. Upon such termination of the ISO Exercise
Limitation, your option shall be deemed a Nonstatutory Stock Option to the extent of the number of vested shares of Common Stock subject to your option that would otherwise exceed the ISO Exercise Limitation. 
 (c) The ISO Exercise Limitation shall terminate, and you may fully exercise your option, as to all shares of Common Stock subject to your option
for which your option would have been exercisable in the absence of the ISO Exercise Limitation upon the earlier of the following events: 
 (i) the date of termination of your Continuous Service, 
 (ii) the day immediately prior to the effective date of a
Corporate Transaction described in subsection 11(c) the Plan in which your option is not assumed or substituted for as provided in the Plan, or 
 (iii) the day that is ten (10) days prior to the Expiration Date of your option. 
 Upon such termination of the ISO Exercise
Limitation, your option shall be deemed a Nonstatutory Stock Option to the extent of the number of shares of Common Stock subject to your option that would otherwise then exceed the ISO Exercise Limitation. 
 5. METHOD OF PAYMENT. Payment of the exercise price is due in full upon exercise of
all or any part of your option. You may elect to make payment of the exercise price in cash or by check or in any other manner permitted by your Grant Notice, which may include one or more of the following: 
 (a) In the Company’s sole discretion at the time your option is exercised and provided that at the time of exercise the Common Stock is
publicly traded and quoted regularly in The Wall Street Journal, pursuant to a program developed under Regulation T as promulgated by the Federal Reserve Board that, prior to the issuance of Common Stock, results in either the receipt of cash
(or check) by the Company or the receipt of irrevocable instructions to pay the aggregate exercise price to the Company from the sales proceeds. 
 (b) Provided that at the time of exercise the Common Stock is publicly traded and quoted regularly in The Wall Street Journal, by delivery of already-owned shares of Common Stock either that you have held for the period
required to avoid a charge to the Company’s reported earnings (generally six months) or that you did not acquire, directly or indirectly from the Company, that are owned free and clear of any liens, claims, encumbrances or security interests,
and that are valued at Fair Market Value on the date of exercise. “Delivery” for these purposes, in the sole discretion of the Company at the time you exercise your option, shall include delivery to the Company of your attestation of
ownership of such shares of Common Stock in a form approved by the Company. Notwithstanding the foregoing, you may not exercise your option by tender to the Company of Common Stock to the extent such tender would violate the provisions of any law,
regulation or agreement restricting the redemption of the Company’s stock. 
 6. WHOLE
SHARES. You may exercise your option only for whole shares of Common Stock. 
  

 7. SECURITIES LAW COMPLIANCE.
Notwithstanding anything to the contrary contained herein, you may not exercise your option unless the shares of Common Stock issuable upon such exercise are then registered under the Securities Act or, if such shares of Common Stock are not then so
registered, the Company has determined that such exercise and issuance would be exempt from the registration requirements of the Securities Act. The exercise of your option must also comply with other applicable laws and regulations governing your
option, and you may not exercise your option if the Company determines that such exercise would not be in material compliance with such laws and regulations. 
 8. TERM. You may not exercise your option before the commencement of its term or after its term expires. The term of your option commences on the Date of Grant and expires upon the
earliest of the following: 
 (a) three (3) months after the termination of your Continuous Service for any reason
other than your Disability or death, provided that if during any part of such three (3) month period your option is not exercisable solely because of the condition set forth in the preceding paragraph relating to “Securities Law
Compliance,” your option shall not expire until the earlier of the Expiration Date or until it shall have been exercisable for an aggregate period of three (3) months after the termination of your Continuous Service; 
 (b) twelve (12) months after the termination of your Continuous Service due to your Disability; 
 (c) eighteen (18) months after your death if you die either during your Continuous Service or within three (3) months after your
Continuous Service terminates; 
 (d) the Expiration Date indicated in your Grant Notice; or 
 (e) the day before the tenth (10th) anniversary of the Date of Grant. 
 If your option is an incentive stock option, note that, to obtain the federal income tax advantages associated with an “incentive stock
option,” the Code requires that at all times beginning on the date of grant of your option and ending on the day three (3) months before the date of your option’s exercise, you must be an employee of the Company or an Affiliate,
except in the event of your death or Disability. The Company has provided for extended exercisability of your option under certain circumstances for your benefit but cannot guarantee that your option will necessarily be treated as an “incentive
stock option” if you continue to provide services to the Company or an Affiliate as a Consultant or Director after your employment terminates or if you otherwise exercise your option more than three (3) months after the date your
employment terminates. 
 9. EXERCISE. 
 (a) You may exercise the vested portion of your option (and the unvested portion of your option if your Grant Notice so permits) during its term by delivering a Notice of Exercise (in a form designated by the
Company) together with the exercise price to the Secretary of the Company, or to such other person as the Company may designate, during regular business hours, together with such additional documents as the Company may then require. 
 (b) By exercising your option you agree that, as a condition to any exercise of your option, the Company may require you to enter into an
arrangement providing for the payment by you to the Company of any tax withholding obligation of the Company arising by reason of (1) the exercise of your option, (2) the lapse of any substantial risk of forfeiture to which the shares of
Common Stock are subject at the time of exercise, or (3) the disposition of shares of Common Stock acquired upon such exercise. 
  

 (c) If your option is an incentive stock option, by exercising your option you agree that you will
notify the Company in writing within fifteen (15) days after the date of any disposition of any of the shares of the Common Stock issued upon exercise of your option that occurs within two (2) years after the date of your option grant or
within one (1) year after such shares of Common Stock are transferred upon exercise of your option. 
 (d) By exercising your
option you agree that the Company (or a representative of the underwriter(s)) may, in connection with the first underwritten registration of the offering of any securities of the Company under the Securities Act, require that you not sell, dispose
of, transfer, make any short sale of, grant any option for the purchase of, or enter into any hedging or similar transaction with the same economic effect as a sale, any shares of Common Stock or other securities of the Company held by you, for a
period of time specified by the underwriter(s) (not to exceed one hundred eighty (180) days) following the effective date of the registration statement of the Company filed under the Securities Act. You further agree to execute and deliver such
other agreements as may be reasonably requested by the Company and/or the underwriter(s) that are consistent with the foregoing or that are necessary to give further effect thereto. In order to enforce the foregoing covenant, the Company may impose
stop-transfer instructions with respect to your shares of Common Stock until the end of such period. The underwriters of the Company’s stock are intended third party beneficiaries of this Section 9(d) and shall have the right, power and
authority to enforce the provisions hereof as though they were a party hereto. 
 10. TRANSFERABILITY.
Your option is not transferable, except by will or by the laws of descent and distribution, and is exercisable during your life only by you. Notwithstanding the foregoing, by delivering written notice to the Company, in a form satisfactory to the
Company, you may designate a third party who, in the event of your death, shall thereafter be entitled to exercise your option. 
 (a)
If your option is an incentive stock option, your option is not transferable, except by will or by the laws of descent and distribution, and is exercisable during your life only by you. Notwithstanding the foregoing, by delivering written notice
to the Company, in a form satisfactory to the Company, you may designate a third party who, in the event of your death, shall thereafter be entitled to exercise your option. 
 (b) If your option is a nonstatutory stock option, your option is not transferable, except (i) by will or by the laws of descent and
distribution, (ii) with the prior written approval of the Company, by instrument to an inter vivos or testamentary trust, in a form accepted by the Company, in which the option is to be passed to beneficiaries upon the death of the trustor
(settlor) and (iii) with the prior written approval of the Company, by gift, in a form accepted by the Company, to your “immediate family” as that term is defined in 17 C.F.R. 240.16a-1(e). The term “immediate family” is
defined in 17 C.F.R. 240.16a-1(e) to mean any child, stepchild, grandchild, parent, stepparent, grandparent, spouse, sibling, mother-in-law, father-in-law, son-in-law, daughter-in-law, brother-in-law, or sister-in-law, and includes adoptive
relationships. Your option is exercisable during your life only by you or a transferee satisfying the above-stated conditions. The right of a transferee to exercise the transferred portion of your option after termination of your Continuous Service
shall terminate in accordance with your right to exercise your option as specified in your option. In the event that your Continuous Service terminates due to your death, your transferee will be treated as a person who acquired the right to exercise
your option by bequest or inheritance. In addition to the foregoing, the Company may require, as a condition of the transfer of your option to a trust or by gift, that your transferee enter into an option transfer agreement provided by, or
acceptable to, the Company. The terms of your option shall be binding upon your transferees, executors, administrators, heirs, successors, and assigns. Notwithstanding the foregoing, by delivering written notice to the Company, in a form
satisfactory to the Company, you may designate a third party who, in the event of your death, shall thereafter be entitled to exercise your option. 
  

 11. RIGHT OF FIRST
REFUSAL. Shares of Common Stock that you acquire upon exercise of your option are subject to any right of first refusal that may be described in the Company’s bylaws in effect at such time the Company elects to
exercise its right. The Company’s right of first refusal shall expire on the Listing Date. 
 12. RIGHT
OF REPURCHASE. To the extent provided in the Company’s bylaws as amended from time to time, the Company shall have the right to repurchase all or any part of the shares of Common Stock you
acquire pursuant to the exercise of your option. 
 13. OPTION NOT A SERVICE
CONTRACT. Your option is not an employment or service contract, and nothing in your option shall be deemed to create in any way whatsoever any obligation on your part to continue in the employ of the Company or an
Affiliate, or of the Company or an Affiliate to continue your employment. In addition, nothing in your option shall obligate the Company or an Affiliate, their respective shareholders, Boards of Directors, Officers or Employees to continue any
relationship that you might have as a Director or Consultant for the Company or an Affiliate. 
 14. WITHHOLDING
OBLIGATIONS. 
 (a) At the time you exercise your option, in whole or in part, or at any time thereafter as
requested by the Company, you hereby authorize withholding from payroll and any other amounts payable to you, and otherwise agree to make adequate provision for (including by means of a “cashless exercise” pursuant to a program developed
under Regulation T as promulgated by the Federal Reserve Board to the extent permitted by the Company), any sums required to satisfy the federal, state, local and foreign tax withholding obligations of the Company or an Affiliate, if any, which
arise in connection with your option. 
 (b) Upon your request and subject to approval by the Company, in its sole discretion, and
compliance with any applicable conditions or restrictions of law, the Company may withhold from fully vested shares of Common Stock otherwise issuable to you upon the exercise of your option a number of whole shares of Common Stock having a Fair
Market Value, determined by the Company as of the date of exercise, not in excess of the minimum amount of tax required to be withheld by law. If the date of determination of any tax withholding obligation is deferred to a date later than the date
of exercise of your option, share withholding pursuant to the preceding sentence shall not be permitted unless you make a proper and timely election under Section 83(b) of the Code, covering the aggregate number of shares of Common Stock
acquired upon such exercise with respect to which such determination is otherwise deferred, to accelerate the determination of such tax withholding obligation to the date of exercise of your option. Notwithstanding the filing of such election,
shares of Common Stock shall be withheld solely from fully vested shares of Common Stock determined as of the date of exercise of your option that are otherwise issuable to you upon such exercise. Any adverse consequences to you arising in
connection with such share withholding procedure shall be your sole responsibility. 
 (c) You may not exercise your option unless the
tax withholding obligations of the Company and/or any Affiliate are satisfied. Accordingly, you may not be able to exercise your option when desired even though your option is vested, and the Company shall have no obligation to issue a certificate
for such shares of Common Stock or release such shares of Common Stock from any escrow provided for herein. 
  

 15. NOTICES. Any notices provided for in your option or the Plan
shall be given in writing and shall be deemed effectively given upon receipt or, in the case of notices delivered by mail by the Company to you, five (5) days after deposit in the United States mail, postage prepaid, addressed to you at the
last address you provided to the Company. 
 16. GOVERNING PLAN DOCUMENT.
Your option is subject to all the provisions of the Plan, the provisions of which are hereby made a part of your option, and is further subject to all interpretations, amendments, rules and regulations which may from time to time be promulgated and
adopted pursuant to the Plan. In the event of any conflict between the provisions of your option and those of the Plan, the provisions of the Plan shall control. 
  

 CARDIOMEMS, INC. 
 STOCK OPTION GRANT NOTICE 
 (2001 EQUITY INCENTIVE PLAN) 
 CardioMEMS, Inc.
(the “Company”), pursuant to its 2001 Equity Incentive Plan (the “Plan”), hereby grants to Optionholder an option to purchase the number of shares of the Company’s Common Stock set forth below. This option is subject to all
of the terms and conditions as set forth herein and in the Stock Option Agreement, the Plan and the Notice of Exercise, all of which are attached hereto and incorporated herein in their entirety. 
  

			
	 Optionholder:
	 	__________________________________________
	 Date of Grant:
	 	 __________________________________________

	 Vesting Commencement Date:
	 	 __________________________________________

	 Number of Shares Subject to Option:
	 	 __________________________________________

	 Exercise Price (Per Share):
	 	 __________________________________________

	 Total Exercise Price:
	 	 __________________________________________

	 Expiration Date:
	 	 __________________________________________

  

					
	Type of Grant:	  	 ̈ Incentive Stock Option1	  	 ̈ Nonstatutory Stock Option

					
		
	Exercise Schedule:	  	Same as Vesting Schedule
		
	Vesting Schedule:	  	[1/4th of the shares subject to the option
shall vest on the one year anniversary of the Vesting Commencement Date.
		
		  	1/48th of the shares subject to the option
shall vest monthly thereafter over the next three years.]
		
		  	[1/48th of the shares subject to the option
shall vest monthly over four year commencing with the Vesting Commencement Date.]
		
	Payment:	  	By one or a combination of the following items (described in the Stock Option Agreement):
		
		  	        By cash or check

 Additional Terms/Acknowledgements: The undersigned Optionholder acknowledges receipt of, and understands
and agrees to, this Grant Notice, the Stock Option Agreement and the Plan. Optionholder further acknowledges that as of the Date of Grant, this Grant Notice, the Stock Option Agreement and the Plan set forth the entire understanding between
Optionholder and the Company regarding the acquisition of stock in the Company and supersede all prior oral and written agreements on that subject with the exception of (i) options previously granted and delivered to Optionholder under the
Plan, and (ii) the following agreements only: 
  

					
	 OTHER AGREEMENTS:
	 	  
	 	
		 	  
	 	

  

									
	CARDIOMEMS, INC.	 		 	OPTIONHOLDER
				
	By:	 	  
	 		 	  

		 	Signature	 		 	Signature
					
	Title:	 	  
	 		 	Date:	 	  

	Date:	 	  
	 		 		 	

 ATTACHMENTS: Stock Option Agreement, 2001 Equity Incentive Plan and Notice of
Exercise 
  

	1	If this is an incentive stock option, it (plus your other outstanding incentive stock options) cannot be first exercisable for more than $100,000 in
any calendar year. Any excess over $100,000 is a nonstatutory option.Rental Agreement dated August 17, 2005

 Exhibit 10.5 
 STATE OF GEORGIA 
 COUNTY OF FULTON: 
 RENTAL AGREEMENT 
 THIS RENTAL AGREEMENT (hereinafter referred to as “Agreement”), is made and entered into as of
this August 17, 2005, (hereinafter referred to as the “Effective Date”), by and between Georgia Advanced Technology Ventures, (hereinafter referred to as “Landlord”), whose address for purposes of this Agreement is 75
Fifth Street, NW, Atlanta, Georgia 30308 and, CardioMems, Inc, (hereinafter referred to as “Tenant”), whose address for purposes of this Agreement is 75 Fifth Street NW, Atlanta, GA 30308 suite 440. 
 WITNESSETH: 
 PREMISES 
  

	1.1	For and in consideration of the rental, terms, provisions and conditions hereinafter set forth to be kept and performed by Tenant, Landlord hereby rents unto Tenant, and Tenant
hereby takes and hires from Landlord, upon the terms, provisions, and conditions hereinafter set forth, the following described real property (hereinafter referred to as “Premises”): 

 Suite – 440 5246 rentable square feet of office space 
 (Measured per BOMA standards based on an 18% common area factor) 
 in the building known as the ATDC
Headquarters at Centergy One located at 75 Fifth Street, N.W., Atlanta, Georgia 30308. Tenant shall have reasonable access to restrooms, conference rooms, and loading dock facilities on a first-come, first-serve basis. A conference room calendar
will be maintained on the ATDC Intranet site. 
 USE OF PREMISES 
  

	2.1	Tenant shall use the Premises solely for the purposes of the general office operations of CardioMems, Inc. Tenant must obtain the prior written approval of Landlord
for any other use of the Premises. At Tenant’s own expense, Tenant shall promptly comply with all building code and other requirements of any local, state or federal law or regulation required by Tenant’s occupancy of the Premises.

  

	2.2	Tenant shall not (i) use the Premises for any illegal purpose, nor for any purpose that is injurious to the health, safety, and welfare of the public or that may jeopardize
Tenant’s insurance coverage of the Premises; or (ii) commit, or suffer to be committed, any waste in or on the Premises; or (iii) create or permit any nuisance in or on the Premises. Tenant hereby covenants to Landlord that no
hazardous substances, as defined by any federal, state, or local law, will be used or generated on the Premises without prior written notice to Landlord and without strict compliance with all local, state, and federal laws and regulations regarding
the same. 

  

	2.3	Tenant agrees to abide by all occupancy rules for Centergy One set forth by the building owner, TUFF ATDC, LLC and its assignees (Exhibit A). 

 RENTAL TERM 
  

	3.1	The Rental Term of this Agreement shall be ninety (90) days commencing on September 1, 2005. 

  

	3.2	Ten days prior to the expiration of the current term, the Rental Term shall be automatically renewed for an additional ninety (90) days unless termination notification is
provide by the Landlord or by the Tenant at least ninety (90) days prior to the expiration to the current term. 

  

	3.3	

  

	3.4	At any point in the initial or subsequent Rental Terms, the Landlord may give 90 days notice of lease termination or Tenant may give 90 days notice of lease termination without
penalty. 

  

 -1- 

 RENTAL 
  

	4.1	For and as rental for the Premises, Tenant agrees to pay Landlord, on or before the first day of each month during the initial and subsequent rental terms,, a Base Monthly Rental
amount of $ 9836.25, calculated upon the following formula, and to keep and perform each and every provision of this Agreement required to be kept and performed by Tenant, each of which shall constitute rental for the Premises. The Base Monthly
Rental amount may be increased during subsequent rental periods. 

 Base Monthly Rental = $ 22.50 per RSF per year x
5246 RSF of office space / 12 months 
                                      = $ 9836.25

 Additional furniture and wall at $2,271.55 per month. Total monthly rental amount of $12,107.80 
  

	4.2	Tenant shall pay to Landlord promptly all rent, and all other charges as provided by this Agreement, as the same become due and payable without offset, deduction, notice or demand.
If such sums are not paid within five (5) days of the due date of such sum, Tenant shall pay to Landlord, as additional rent, a late charge equal to 1.5 percent of such overdue sum. If any check delivered by Tenant to Landlord is dishonored,
Tenant shall pay to Landlord a charge equal to the maximum amount lawfully charged for dishonored checks. Any payment made by a dishonored check shall be deemed to be late. Returned checks may not be redeemed by a personal check, but must be
redeemed by cash, cashier’s check, certified check or money order. All charges under this section 4.2 shall be deemed to constitute additional rent due and payable upon notice from Landlord to Tenant, and Landlord shall have all the rights and
remedies with respect thereto as Landlord has for the nonpayment of rent. 

  

	4.3	Checks shall be made payable to Georgia Advanced Technology Ventures and shall be sent to the attention of the Facilities Manager, Georgia Advanced Technology Ventures, Suite
100, 75 Fifth Street, NW, Atlanta, GA 30308. 

 SECURITY DEPOSIT 
  

	5.1	As security for the full and faithful performance by Tenant of each and every one of its duties and obligations under this Agreement, Tenant agrees to deposit with Landlord, on the
date hereof, and to maintain at all times with Landlord during the entire term of this Agreement, a security deposit equal to one month’s rental. 

  

	5.2	Upon default by Tenant of any of its obligations under this Agreement, not cured within fifteen (15) days of the date of such written notice of default, Landlord may use, apply
or retain the whole or any part of the security deposit for the payment of any rent in default, or for any expenditure made by Landlord by reason of Tenant’s default of any of Tenant’s obligations of this Agreement, including, but not
limited to, any damages or deficiency due to reletting of the Premises, whether such damages or deficiency accrue before or after summary proceedings or other reentry by Landlord. In the event Landlord uses, applies, or retains the whole or any part
of Tenant’s security deposit, Tenant shall pay to Landlord immediately such amount that will fulfill Tenant’s obligation hereunder to maintain at all times a security deposit equal to one month’s rental. 

  

	5.3	If upon the termination of this Agreement, Tenant shall have kept all of its duties and obligations hereunder, Landlord shall return to Tenant all the security so deposited with
Landlord. 

  

 -2- 

 PARKING 
 Additional parking spaces may be purchased as available from the Landlord. Parking fees are due and payable on the 1st of each month. The current rate for the Centergy One deck is $720.00 per year per space ($60.00 per month per space). 
  

	6.1.1	Tenant shall comply with all parking rules and regulations of the Centergy development and the Georgia Institute of Technology. 

 UTILITIES 
  

	7.1	Landlord shall be responsible for the payment of all utility bills for normal office use of the Premises by Tenant, including water, sewer, natural gas. Normal office use of
electricity shall include use of computer terminals, desk calculators, and lab testing equipment using not more than 110 volts, 15 amps power. Landlord retains the option to meter separately or to estimate any utility usage in excess of normal
office use, and Tenant shall be exclusively responsible for payment of the such excess usage. Tenant shall be solely responsible for obtaining, maintaining, and paying for telephone and data network service for the Premises.

  

	7.2	Heating, ventilating and air conditioning systems shall be kept operating by Landlord during normal business hours Monday through Friday, 8 AM – 6 PM and Saturday, 8 AM - Noon.
After hour HVAC is available; however, Tenant shall be responsible for additional energy use charges during after hour use. Charges will be set by Centergy Development. 

  

	7.3	Landlord shall provide a garbage receptacle and garbage pick-up at Landlord’s expense. Landlord shall provide janitorial service for the Premises. 

  

	8.1	Intentionally Blank 

 MAINTENANCE AND REPAIRS 

 

	9.1	Landlord agrees to maintain and keep in good repair the roof, foundations, and exterior walls of the building in which the Premises are located, and the structure of the walls
surrounding the Premises, exclusive of any repairs made necessary by the actions of Tenant or Tenant’s agents, employees, or invitees. 

  

	9.2	Landlord warrants that the premises shall meet and remain current with all ADA Standards as of the commencement date of the lease through it’s Expiration and/or Extension.

  

	9.3	Landlord gives to Tenant exclusive control of the Premises and shall not be required to supply any maintenance or repair to or for the Premises or to inspect the same. Tenant shall
report promptly to Landlord all items that Tenant contends Landlord is under a duty to provide maintenance and repair. 

  

	9.4	Tenant shall not make improvements or alterations to the Premises without the prior express written consent of Landlord, which consent will not be unreasonably withheld. Any such
improvements or alterations approved by Landlord must comply with all existing federal, state, and local laws and must be maintained and repaired by Tenant. Upon the expiration or termination of this Agreement, all improvements or additions placed
in or erected on the Premises by Tenant, whether or not affixed or attached to the Premises, shall vest in and become the property of Landlord, without further notice, action taken, or instrument executed; provided, however, Tenant may remove all of
Tenant’s personal property from the Premises on or before the expiration or termination of this Agreement. Tenant shall repair all damage to the Premises resulting from the removal of Tenant’s personal property. Tenant agrees that all of
Tenant’s personal property in or on the Premises is located there at Tenant’s risk and Landlord shall not be liable for any damage thereto or loss thereof. 

  

 -3- 

	9.5	Any property acquired by Tenant through Landlord or acquired by Landlord for the use of Tenant shall become and remain the property of Landlord and shall not be removed by Tenant,
or its employees, agents, licensees, or invitees, from the Premises. 

  

	9.6.1	Landlord’s obligations under this paragraph 9 are subject to reduction depending upon the availability of funds appropriated for the purposes herein. 

INSPECTION 
  

	10.1	Tenant shall permit Landlord, its agents and employees, without prior notice, to enter into and upon the Premises at all reasonable times for the purpose of inspecting the Premises
and making any necessary repairs or alterations to electrical wiring, heating and cooling systems, or plumbing, and other similar repairs and alterations. 

 INSURANCE AND INDEMNITY 
  

	11.1	Indemnification Agreement: 

 Tenant hereby waives,
releases, relinquishes, discharges and agrees to indemnify, protect, save harmless, Georgia Advanced Technology Ventures, Inc., the University System of Georgia and Board of Regents, the State of Georgia and its departments, agencies and
instrumentalities (including the State Tort Claims Trust Fund, the State Authority Liability Trust Fund, the State Employee Broad Form Liability Fund, the State Insurance and Hazard Reserve Fund, and other self insured funds, hereinafter
collectively referred to as the “Fund”) and all of their respective officers, employees, directors and agents (hereinafter collectively referred to as the “Indemnitees”) of and from any and all claims, demands, liabilities,
losses, costs or expenses for any loss including but not limited to bodily injury (including death), personal injury, property damage, expenses, and attorneys’ fees, caused by, growing out of, or otherwise happening in connection with this
contact, due to any act or omission (whether intentional or negligent) on the part of the Tenant, it’s agents, employees or others working at the direction of Tenant or on its behalf, or due to any breach of this contract by the Tenant, or due
to the application or violation of any pertinent Federal, State, or local law, rule or regulation. This indemnification extends to the successors and assigns of the Tenant, and this indemnification survives the termination of the contract and the
dissolution or, to the extent allowed by law, the bankruptcy of the Tenant. If and to the extent such damage or loss (including costs and expenses as covered by this indemnification is covered by the Fund established and maintained by the State of
Georgia Department of Administrative Services (DOAS), the Tenant agrees to reimburse the Fund for such monies paid out of the Fund. 
  

	11.1.1	This indemnification applies whether: (a) the activities involve third parties or employees or agents of the Tenant or of the Indemnitees. 

  

	11.1.2	This indemnification does not apply to the extent of the sole negligence of the Indemnitees. This indemnification is subject to an overall limitation of $1,000,000.00 so long as the
insurance required in Section 11.2.2(a) is in full force and effect. 

  

	11.1.3	To the full extent permitted by the Constitution and the laws of the State of Georgia and the terms of the Fund, the Tenant and its insurers waive any right of subrogation against
the Indemnitees, the Fund and insurers participating thereunder, to the full extent of this indemnification. 

  

	11.2	Insurance Requirements: 

  

	11.2.1	Insurance Certificates. The Tenant shall procure the insurance policies identified below at the Tenant’s own 

  

 -4- 

 expense and shall furnish the Landlord an insurance certificate listing the agency as the certificate
holder. The insurance certificate must document that the liability insurance coverage purchased by the Tenant includes contractual liability coverage to insure the indemnity agreement as stated. In addition, the insurance certificate must provide
the following: 
 (a) Name and address of authorized agent 
 (b) Name and address of insured 
 (c) Name of insurance company 
 (d) Description of coverage in standard terminology 
 (e) Policy name 
 (f) Policy number 
 (g) Limits of liability 
 (h) Name and address of Landlord as certificate holder 
 (i) Acknowledgment of notice of cancellation to Landlord 
 (j) Signature of authorized agent 
 (k) Telephone number of authorized agent 
 (l) Details of special policy exclusions in comments section of Certificate 
  

	11.2.2	Insurance Coverages. The Tenant also agrees to purchase and have the authorized agent state on the insurance certificate that the following types of insurance coverages,
issued pursuant to O.C.G.A. Section 50-21-37, have been purchased by the Tenant: 

 (a) Commercial General Liability
Insurance Policy (CGL). Tenant shall procure and maintain a primary Commercial General Liability Insurance Policy, including products and completed operation liability and contractual liability coverage, with limits of not less than $1,000,000
per person and $1,000,000 per occurrence covering bodily injury, property damage liability and personal injury. The policy or policies shall name the officers, agents, and employees of the Board of Regents as additional insureds, but only with
respect to claims which are not covered by the Georgia Tort Claims act, O.C.G.A. Section 50-21-20 et seq. The CGL policy must provide primary limits over any other liability policy provided by the State for any claims not covered by the Georgia
Tort Claims Act. However, the CGL policy must indemnify the State for any claims covered by the Georgia Tort Claims Act. The policy of policies must be on an “occurrence” basis unless waived by the State. The CGL policy shall include
contractual liability coverage, which shall be endorsed to state that indemnity obligations specified in this agreement are insured by the carrier. The CGL policy purchased by the Tenant must be issued by a company authorized to conduct business in
the State of Georgia or by a company acceptable to the State if the company is an alien insurer. The CGL policy must be endorsed to include separate aggregate limits per project. 
 (b) Tenant is responsible for insuring at its sole expense its own property which may be brought upon the Premises, and subtenant shall be responsible for
insuring any of their property brought upon the Premises. 
 DESTRUCTION OR DAMAGE TO PREMISES 
  

	12.1	If the Premises are totally destroyed or rendered untenantable by storm, fire, earthquake, hurricane, or other natural catastrophe, this Agreement shall terminate as of the date of
such total destruction or untenantability, with no obligation of Landlord to rebuild or provide other rental premises for Tenant. Any rental or other obligations accrued by or to the parties to this Agreement shall be accounted for between Landlord
and Tenant as of the date when the Premises were destroyed or rendered untenantable. 

  

	12.2	If the Premises are partially destroyed or rendered partially untenantable by storm, fire, earthquake, hurricane, or other natural catastrophe, Tenant shall have the option to elect
either to terminate this Agreement by written notice to Landlord in accordance with Paragraph 24 or to continue this Agreement in force with an appropriate abatement of rent and without obligation of Landlord to repair, restore, or rebuild the
Premises at any time, even if Tenant elects to continue this Agreement. The Premises shall be considered partially destroyed or rendered partially untenantable when at least ten per cent (10%) but less than one hundred per cent (100%) of
the Premises are destroyed or rendered untenantable. 

  

 -5- 

 TRANSFER, SUBLETTING AND ASSIGNMENT 
  

	13.	Tenant shall not transfer, assign, or sublet this Agreement or any right or privilege of Tenant under this Agreement without the prior, express, written consent of Landlord.
Landlord, in its sole discretion, may withhold or refuse to give its consent to any proposed transfer, subletting, or assignment and to any proposed use or occupancy by any party other than Tenant. Any transfer, subletting, or assignment without the
prior, express, written consent of Landlord shall be void and shall, at the option of Landlord terminate this Agreement. Landlord’s consent to one transfer, subletting, assignment, use or occupancy of the Premises by a party other than Tenant
shall not constitute a waiver of Landlord’s rights in this Paragraph, and each subsequent transfer, subletting, assignment, use or occupancy of the Premises by a party other than Tenant shall require Landlord’s consent in accordance with
this Paragraph. 

 DEFAULT 
  

	14.1	If Tenant defaults in the payment of monetary rental or any other monetary obligation to Landlord and remains in default for ten (10) calendar days after the date of service of
notice of such default by Landlord on Tenant; or if Tenant defaults in the performance of any other covenant or provision of this Agreement required to be complied with by Tenant and remains in default for thirty (30) calendar days after the
date of service of notice of such default by Landlord on Tenant; or if Tenant defaults in the payment of any monetary obligation to Landlord’s cooperative organization, the Georgia Tech Research Corporation (hereinafter referred to as
“GTRC”), including without limitation the L-Account Agreement between Tenant and GTRC, and remains in default for ten (10) calendar days after the date of service of notice of such default by GTRC; then, in any such event, Landlord
may at once terminate this Agreement by written notice to Tenant. 

  

	14.2	Upon such termination, Tenant shall surrender the Premises to Landlord and remove all personal property from the same and, without requiring legal action to be taken by Landlord,
Landlord may enter in and upon the Premises and take immediate possession and control of the Premises to the complete exclusion of Tenant. Landlord’s failure to exercise its rights after one or more defaults of Tenant shall not be construed as
a waiver of Landlord’s rights upon any subsequent default. 

 EXTERIOR SIGNS 
  

	15.1	Tenant shall not place signs or displays off the Premises, including the roof, exterior doors, and exterior walls of the building in which the Premises are located, or in the
windows of the Premises without the prior, express, written consent of Landlord, which consent will not be unreasonably withheld. 

 FIXTURES AND PERSONAL PROPERTY 
  

	16.1	Tenant may install and operate in and on the Premises such fixtures and personal property as is required for Tenant’s permitted use of the Premises, subject to the prior,
express, written approval of Landlord. 

 ENTRY OF LANDLORD FOR RELETTING 
  

	17.1	During the thirty (30) day period immediately preceding the termination of this Agreement, Landlord may enter the Premises at any time to show the Premises to prospective
tenants. 

 NO ESTATE 
  

	18.1	This Agreement shall create the relationship of landlord and tenant, otherwise known as a usufruct, and no estate shall pass from landlord. Tenant’s interest in this rental
agreement is not subject to levy and sale. 

  

 -6- 

 TERMINATION AND HOLDING OVER 
  

	19.1	Tenant shall vacate the Premises promptly upon termination of this Agreement. Any holding over or continued use or occupancy of the Premises by Tenant after termination of this
Agreement without the express written consent of Landlord shall not constitute a Tenancy-At-Will, but Tenant shall be a Tenant-At-Sufferance and shall be required to vacate the Premises immediately without notice. There shall be no renewal or
extension of the term of this Agreement by operation of law. Tenant agrees that the provisions of O.C.G.A. §44-7-50 et. seq. shall apply, permitting summary dispossession. 

  

	19.2	Upon any such termination, Tenant shall surrender the Premises to Landlord and remove all personal property from the same and, without requiring legal action to be taken by
Landlord, Landlord may enter in and upon the Premises and take immediate possession and control of the Premises to the complete exclusion of Tenant. 

  

	19.3	Tenant agrees to return the premises to the Landlord upon the expiration or termination of this rental agreement in as good condition and repair as when first received; normal wear
and tear, excepted. 

 NO ABANDONMENT 
  

	20.1	Tenant shall occupy the Premises continuously throughout the term of this Agreement and shall not for any cause whatsoever, unless otherwise specifically permitted under this
Agreement, desert, surrender, abandon, or cease operation of the Premises during the term of this Agreement. 

 RIGHTS
CUMULATIVE 
  

	21.1	All rights, powers, and privileges conferred by this Agreement shall be cumulative and not restrictive of those rights, powers, and privileges conferred by law.

 ATTORNEYS FEES 
  

	22.1	In the event Landlord uses the services of an attorney to collect any monetary amounts required under this Agreement, Tenant shall pay ten percent (10%) of such amount in
addition as attorney’s fees. 

 NO WAIVER 
  

	23.1	No failure of Landlord to exercise any right or power given to Landlord under this Agreement, or to insist upon strict compliance by Tenant with the provisions of this Agreement,
and no custom or practice of Landlord or Tenant at variance with the provisions of this Agreement, nor acceptance by Landlord of rent or any other payments from any person other than Tenant, shall constitute a waiver of Landlord’s right to
demand exact and strict compliance by Tenant with the terms and conditions of this Agreement. 

 TENANT BUSINESS RECORDS

  

	24.1	Not required. 

 NOTICES 
  

	25.1	All notices and other communications, hereinafter collectively referred to as “notices,” required by this Agreement to be secured from or given by either party to the
other party shall be in writing and the original of said notice shall be delivered either: (a) by hand delivery to the recipient party at such party’s address; or 

  

 -7- 

 (b) sent by United States Certified Mail - Return Receipt Requested, postage prepaid and addressed to the
recipient party at such party’s address. If sent by United States Certified Mail - Return Receipt Requested, the sender of the notice shall “show to whom, date and address of delivery” of said notice on the returned receipt. The day
upon which such notice is hand delivered or so mailed shall be deemed the date of service of such notice. Any notice, so hand delivered or mailed, the text of which is reasonably calculated to apprise the recipient party of the substance thereof,
shall be deemed sufficient under this Agreement. Either party hereto, by proper notice, may at any time and any number of times designate a different address to which notices to said party shall be given. 
  

			
	To Landlord:	 	To Tenant:
		
	 Georgia Advanced Technology Ventures 
 75 Fifth
Street, NW Suite 100
 Atlanta, Georgia 30308
 Attn: General
Manager
	 	 CardioMems, Inc
 75 Fifth Street, NW
 Suite 440
 Atlanta, Georgia 30308

 TIME IS OF ESSENCE 
  

	26.1	Time is of the essence of this Agreement. All time limits stated herein are likewise of the essence. 

 ENTIRE AGREEMENT 
  

	27.1	This Agreement constitutes the full, complete and entire agreement between Landlord and Tenant; no agent, employee, officer or representative of Landlord or Tenant has authority to
make, or has made, any statement, agreement, representation or contemporaneous agreement, oral or written, in connection herewith modifying, adding to, or changing the covenants, terms and provisions of this Agreement. No modification or amendment
of this Agreement shall be binding unless such modification or amendment is in writing, signed by Landlord and Tenant, and by reference incorporated into this Agreement. 

 GOVERNING LAW 
  

	28.1	This Agreement shall be governed by, construed under, and performed and enforced in accordance with the laws of the State of Georgia. 

  

 -8- 

 IN WITNESS WHEREOF, Landlord and Tenant, acting by and through their duly authorized representatives, have caused these
presents to be signed, sealed, and delivered all as of the date hereof. 
  

			
	LANDLORD
	Georgia Advanced Technology Ventures
		
	BY:	 	  

	Business Operations Manager

  

			
	TENANT	 	
	  
 /s/ Sandeep Yadav

	Name:	 	Yadav
	Title:	 	CFO
	Date:	 	10-20-05
	
	(Corporate Seal Affixed Here)

 Signed, sealed, and delivered 
 as to Landlord in the presence of: 
 Official Witness, Notary Public     Date 
 My Commission Expires: 
 (Notary Public Seal Affixed Here) 
  

 -9- 

 GUARANTY 
 On this 20th day of Oct 2005, in consideration of Landlord’s agreement to enter into the above Rental
Agreement with Tenant and in recognition of Landlord’s unwillingness to enter into the Rental Agreement without this Guaranty, the undersigned Guarantor guaranties the payment of rent and performance by Tenant, Tenant’s heirs, executors,
administrators, successors, or assigns of all covenants and agreements of the above Rental Agreement. 
  

			
	GUARANTOR
	
	 /s/ Sandeep Yadav

	Name:	 	Yadav
	Title:	 	CFO
	Date:	 	10-20-05

 Signed, sealed, and delivered 
 as to Landlord in the presence of: 
 Official Witness, Notary Public      Date 
 My Commission Expires: 
 (Notary Public Seal Affixed Here) 
  

 -10- 

 EXHIBIT A 
 Rules and Regulations 
 1. The sidewalks and public portions of the Building, such as entrances,
passages, courts, elevators, vestibules, stairways, corridors or halls, shall not be obstructed or encumbered by Tenant or used for any purpose other than ingress and egress to and from the Premises. 
 2. No curtains, blinds, shades, louvered openings or screens shall be attached to or hung in, or used in connection with, any window or door of the
Premises, without the prior written consent of Landlord. 
 3. No sign, advertisement, notice or other lettering shall be exhibited,
inscribed, painted or affixed by Tenant on any part of the outside of the Premises or Building or on corridor walls. Signs on entrance door or doors shall conform to Building standard signs, samples of which are on display in Landlord’s Rental
office. Signs on doors shall, at Tenant’s expense, be inscribed, painted or affixed for each tenant by sign makers reasonably approved by Landlord. In the event of the violation of the foregoing by Tenant, Landlord may remove same without any
liability and may charge the expense incurred by such removal to Tenant. 
 4. The sashes, sash doors, skylights, windows, heating,
ventilating and air conditioning vents and doors that reflect or admit light and air into the halls, passageways or other public places in the Building shall not be covered or obstructed by Tenant, nor shall any bottles, parcels or other articles be
placed on the window sills. 
 5. The water and wash closets and other plumbing fixtures shall not be used for any purposes other than those
for which they were constructed, and no sweepings, rubbish, rags or other substances shall be thrown therein. All damages resulting from any misuse of the fixtures shall be borne by Tenant, if caused by it or its agents, employees, contractors,
licensees or invitees. 
 6. Tenant shall not in any way deface any part of the Premises or the Building. Tenant shall not lay linoleum, or
other similar floor covering, so that the same shall come in direct contact with the floor of the Premises, and, if linoleum or other similar floor covering is desired to be used, an interlining of builder’s deadening felt shall be first
affixed to the floor by a paste or other material, soluble in water, the use of cement or other similar adhesive material being expressly prohibited. 
 7. No bicycles, vehicles or animals (except Seeing Eye dogs) of any kind shall be brought into or keep in or about the Premises. No cooking shall be done or permitted by Tenant on the Premises except in conformity
with law and then only in the utility kitchen, if any, as set forth in Tenant’s layout, which is to be primarily used by Tenant’s employees for heating beverages and light snacks. Tenant shall not cause or permit any unreasonably unusual
or objectionable odors to be produced upon or permeate from the Premises. 
 8. No space in the Building shall be used for manufacturing or
distribution, or for the storage of merchandise or for the sale of merchandise, goods or property of any kind at auction. 
 9. Tenant shall
not make, or permit to be made, any unseemly or unreasonably disturbing noises or unreasonably disturb or interfere with occupants of the Building or neighboring buildings or premises or those having business with them, whether by the use of any
musical instrument, radio, talking machine, unmusical noise, whistling, singing, or in any other way. 
 10. Neither Tenant, nor any of
Tenant’s agents, employees, contractors, licensees or invitees, shall at any time put up or operate fans or electrical heaters or bring or keep upon the Premises flammable, combustible or explosive fluid, or chemical substance, other than
reasonable amounts of cleaning fluids or solvents required in the normal operation of Tenant’s business offices. No offensive gases or liquids will be permitted. 
 11. No additional locks or bolts of any kind shall be placed upon any of the doors or windows by Tenant, nor shall any changes be made in existing locks or the mechanism thereof, without the prior written reasonable
approval of Landlord and unless and until a duplicate key is delivered to Landlord. Tenant shall, upon termination of its tenancy, restore to Landlord all keys of stores, offices and toilet rooms, either furnished to, or otherwise procured by,
Tenant, and in the event of the loss of any keys so furnished, Tenant shall pay to Landlord the reasonable cost thereof. 

 12. All moves in or out of the Premises, or the carrying in or out of any safes, freight, furniture or
bulky matter of any description, must take place during the hours which Landlord or its agent may reasonably determine from time to time. Only the Building freight elevator shall be used for such purposes. Tenant will ensure that movers take
necessary measures reasonably required by Landlord to protect the Building (e.g., windows, carpets, walls, doors and elevator cabs) from damage. Landlord reserves the right to inspect all freight to be brought into the Building and to exclude from
the Building all freight which violates any of these Rules and Regulations or the Lease of which these Rules and Regulations are a part. 
 13. Tenant shall not place any furniture, accessories or other materials on any balconies located within or adjacent to the Premises without having obtained Landlord’s express written approval thereof in each instance. 
 14. Landlord shall have the right to prohibit advertising by Tenant which in Landlord’s reasonable opinion tends to impair the reputation of the
Building or its desirability as a building for offices, and upon written notice from Landlord, Tenant shall refrain from or discontinue such advertising. 
 15. Landlord reserves the right to exclude from the Building at all times, other than business hours, all persons who do not present a pass to the Building signed by Tenant. Tenant shall be responsible for all persons
to whom it issues such a pass and shall be liable to Landlord for all acts of such persons. 
 16. The Premises shall not be used for lodging
or sleeping or for any immoral or illegal purpose. 
 17. The requirements of Tenant will be attended to only upon application at the
management office for the Building. Building employees shall not perform any work or do anything outside of their regular duties, unless under special instructions from the office of Landlord. 
 18. Canvassing, soliciting and peddling in the Building are prohibited, and Tenant shall cooperate to prevent the same. 
 19. There shall not be used in any space, or in the public halls of the Building, either by Tenant or by its jobbers or others, in the delivery or
receipt of merchandise, any hand trucks, except those equipped with rubber tires and side guards. No hand trucks, mail carts or mail bags shall be used in passenger elevators. 
 20. All paneling or other wood products not considered furniture shall be of fire retardant materials. Before installation of such materials
certification of the materials’ fire retardant characteristics shall be submitted to Landlord or its agents, in a manner satisfactory to Landlord. 
 21. Tenant shall not employ any persons other than the janitors retained by Landlord (who will be provided with passkeys into the offices) for the purpose of cleaning or taking charge of the Premises. It is understood
and agreed that except to the extent proven to be caused by the gross negligence or willful misconduct of Landlord, Landlord shall not be responsible to any tenant for any loss of property from rented premises, however occurring, or for any damage
done to furniture or other effects of any tenant by the janitor or any of its employees. 
 22. No sunscreen or other films shall be applied
to the interior surface of any window glass. All glass, locks and trimmings in or upon the doors and windows of the Building shall be kept whole, and when any part thereof shall be broken, the same shall be immediately replaced or repaired and put
in order at Tenant’s expense under the reasonable direction and to the reasonable satisfaction of Landlord, and shall be left whole and in good repair. 
 23. Landlord will post on the Building directories three names only for Tenant at no charge. All additional names which Tenant shall desire put upon said directories must be first reasonably consented to by Landlord,
and if so approved, a reasonable charge to Tenant will be made for each additional listing as prescribed by Landlord to be paid to Landlord by Tenant. 
 24. Landlord reserves all vending rights for the Building as a whole. Tenant reserves vending rights with respect to its operations within the Premises. 

 25. Landlord reserves the right to modify or delete any of the foregoing Rules and Regulations and to
make such other and reasonable rules and regulations as in its reasonable judgment may from time to time be needed for the safety, care and cleanliness of the Centergy development, and for the preservation of good order therein. Landlord shall not
be responsible to any tenant for the non-observance, or violation, of any of these Rules and Regulations by other tenants, but Landlord shall not discriminate in its enforcement of these Rules and Regulations. 
 26. Parking facilities supplied by Landlord for Tenant, if any, shall be used by vehicles that may occupy a standard parking area only. Moreover, the use
of such parking facilities shall be limited to normal business parking and shall not be used for a continuous parking of any vehicle regardless of size. 
 27. The Building shall be a smoke-free environment, and Tenant’s employees, agents, contractors, licensees and invitees shall refrain from smoking in the Premises, the common areas of the Building, or on the
Building grounds, except in those areas, if any designated by Landlord as smoking areas. 
 28. Tenant shall not install any wireless access
points within or outside their leased area without written permission from the landlord. 

 [ATDC LETTERHEAD] 
 October 18, 2005 
 CardioMems, Inc. 
 75 Fifth
Street, NW 
 Atlanta, GA 30332 
 Dear CardioMems, Inc

 This letter will serve as Lease Amendment 1 to your existing lease dated June 1, 2005. 
 Commencing October 10, 2005, CardioMems, Inc, continued to occupy suite 440 (5246 rentable square feet of office space), and acquired and occupied suite 460 (1337 rentable square feet of office space) at 75 Fifth
Street, NW, Atlanta, GA 30308 
 Base Monthly rental rate is $12,343.12 
 ($22.50 per RSF per year). 
 Please make your check payable to Georgia Advanced Technology Ventures (GATV)

 Your signature will serve as your agreement. If there are any questions, please feel free to contact me at 894-0331. 
  

	
	Sincerely,
	
	 /s/ Beverly D. Hutchinson

	Beverly D. Hutchinson
	Administrative Manager
	
	 /s/ Sandeep Yadav

	Guarantor Signature
	
	Date:

 [ATDC LETTERHEAD] 
 March 6, 2006 
 CardioMems, Inc 
 75 Fifth
Street, NW 
 Atlanta, GA 30308 
 Dear Mr. Yadav, 
 This letter will serve as Lease Amendment Number 3 to your existing lease dated October 18, 2005 
 Commencing April 1, 2006, CardioMems will continue to occupy suites 440, 460 (6583 rentable square feet of office space), and acquire and occupy suites 325 (Venture Suite), 470 (2260 rentable square feet of
office space) on the date of completion of space preparation and readiness for occupancy, at 75 Fifth Street, NW, Atlanta, GA 30308. 
 Base Monthly
rental rate for suites 440, 460, & 325 is $13,118.12 
 ($22.50/RSF for suites 440 & 460, $775.00/Flat Rate for suite 325), additional
furniture and wall $2271,55. Additional office $80.00 per office x 2 = $160.00 
 $24.50/RSF for suite 470 upon occupancy. 
 Furniture lease cost for suite 470 are to be determined. Parking rate is $720.00 for each permit per year at $60.00 per month. 
 Parking rate will increase to $720.00 per year per parking permit ($60.00) per month per space). 
 Please make your check payable to Georgia Advanced Technology Ventures (GATV) 
 Your signature will
serve as your agreement. If there are any questions, please feel free to contact me at 894-0331. 
 Sincerely, 
 /s/ Beverly D. Hutchinson 
 Beverly D. Hutchinson 
 Administrative Manager 
 /s/ Sandeep Yadav 
 Guarantor Signature 
 Date: 03/15/2006 

 November 14, 2006 
 CardioMEMS, Inc. 
 75 Fifth Street, NW 
 Suite 440 
 Atlanta, GA 30308 
 Dear
CardioMEMS, 
 This letter will serve as Lease Amendment Number 4 to your existing lease dated October 18, 2005. 
 Commencing November 14, 2006, CardioMEMS, Inc. will continue to occupy Suites 440 (5,246 RSF), 460 (1,337 RSF), 325 (Venture Suite), and 470 (2260 RSF), and will
acquire and occupy Suite 333 (1,077 RSF) of office space at 75 Fifth Street, NW, Atlanta, GA 30308. 
 The total monthly charge for these suites is
$23,198.59. Please see the chart below for a breakdown of the costs. 
  

														
	Suite #	  	RSF	  	Cost/RSF	  	 Monthly
 Rent
	  	 Furniture Charge
	  	 Total
 Monthly
 Charge

	325	  	VS	  	 	n/a	  	$	775.00	  		  	$	775.00
	333	  	1077	  	$	21.00	  	$	1,884.75	  	 $460 (7 desk sets at $60/month plus 2
 bookcases at $15/month and 1 small
 lateral file cabinet at $10/month)
	  	$	2,344.75
	440	  	5246	  	$	22.50	  	$	9,836.25	  	$2,271.55	  	$	12,107.80
	460	  	1337	  	$	22.50	  	$	2,506.88	  	$160 ($80/office for 2 offices	  	$	2,666.88
	470	  	2260	  	$	24.50	  	$	4,614.17	  	 $690 ($600 for desks; 2 file cabinets @
 $15/each & 6 small cabinets @ $10/each)
	  	$	5,304.17
		  		  			  			  		  	 	 
		  		  			  			  	Total Monthly Charges	  	$	23,198.59
		  		  			  			  		  	 	 

 The parking rate is $720.00 per year per parking permit. Please note the modifications to Section 6.1 of the
CardioMEMS lease: 
 6.1 
 Landlord will provide 2.5 unreserved parking spaces per 1000 rentable square feet (leased) that the Tenant may lease at the current subsidized parking rate. Additional parking spaces may be leased as available from the Landlord at the full
regular rate. Parking fees are due and payable on the 1st of each month. The current subsidized parking rate is
$720.00 per year per space ($60.00 per month per space). 

 Please note the modification to 4.2 of the CardioMEMS lease: 
 4.2 
 If such sums are not paid within five
(5) days of the due date, the Tenant shall pay to Landlord, as additional to rent, a late charge equal to 5% of such overdue sum. 
 Please make your
check payable to Georgia Advance Technology Ventures (GATV). 
 Your signature will serve as your agreement. If there are any questions, please feel free to
contact me at 404-894-0331. Thank you. 
 Sincerely, 
 Beverly
D. Hutchinson 
 Administrative Manager 
 Guarantor Signature:
                                        
                 Date:

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