Document:

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                                                                   Exhibit 10.30

February 8, 2000

Mr. Domenic Micale
1400 Providence Highway, Bldg. 2
Norwood, MA 02062

Dear Domenic:

This letter will evidence the terms of a retention bonus arrangement between you
and UroMed Corporation ("UroMed").

UroMed agrees that if you are an employee of the Company on February 28th 2002
(the "Retention Date"), UroMed will pay you a cash bonus in the amount of
$40,000 (the "Retention Bonus"). In the event that prior to the Retention Date
              ---------------
your employment is terminated for death or disability (as defined below), UroMed
will pay you or your estate a pro rata portion of the Retention Bonus based on
                              --- ----
the time elapsed between now and the date of such termination as compared to the
total period between now and the Retention Date.

You acknowledge that if your employment terminates for any other reason prior to
the Retention Date, including a termination by UroMed for any reason or no
reason at all, you will not be entitled to receive any portion of the Retention
Bonus. In addition, this letter is not intended to imply that you are anything
other than an "at will" employee of UroMed.

For purposes of the letter "total disability" is the same as that defined in
your UroMed Long Term Disability Policy.

Any payment of the Retention Bonus will be subject to applicable withholding.

This letter may not be amended or modified except by a writing signed by both of
us. This letter expresses our entire understanding regarding the Retention Bonus
and supersedes all prior discussions, understandings, or agreements, written or
oral, regarding the Retention Bonus.

Please sign where indicated below to confirm our agreement.

Sincerely yours,

UROMED CORPORATION

By: /s/ Dan Muscatello
    ------------------

Name:   Dan Muscatello

Title:  President and CEO

Agreement confirmed:

    /s/ Domenic Micale
    -------------------

Name:   Domenic Micale<PAGE>

                                                                   Exhibit 10.31

October 17, 2000

Domenic Micale
C/o UroMed Corporation
1400 Providence Highway
Norwood, MA 02062

Re:  Salary Benefit
     --------------

Dear Domenic:

        With this letter, UroMed (the "Company") is offering to you a salary
continuation benefit to provide you further protection in the event that the
Company merges with, acquires or is acquired by another company, or engages in
any other activity or transaction which results in the elimination of your
position, for any other reason other than your negligence (each, a "Change
                                                                    ------
Event"). Upon the occurrence of a Change Event, if you are not offered continued
-----
employment in a substantially similar position as currently held by you, within
the greater Boston area, the Company agrees that it will continue to pay you
your then current base salary for a period of six (6) months from the date of
the consummation of the Change Event, in accordance with the Company's then
current payroll practices and net of tax and other required withholding.

        By signing below, you agree that, in consideration of the Company's
commitment to make such continued salary payments to you, in order to facilitate
the Company's transition following a Change Event, if the Company so requests,
you will continue to work for the Company for a period of six (6) months
following the consummation of the Change Event.

        This letter will only apply to any Acquisitions Event occurring prior
to December 31, 2003. In addition, this letter is not intended to create any
commitment on behalf of the Company to continue your employment for any
particular period before or after a Change Event.

                                   Very truly yours,

                                   /s/ Dan Muscatello      October 17, 2000
                                   -------------------     --------------------
                                   Dan Muscatello          Date
                                   President and CEO

Accepted and Agreed:

/s/ Domenic Micale                 October 17, 2000
------------------                 ----------------
Domenic Micale                     Date<PAGE>

                                                                   Exhibit 10.32

January 5, 2001

Mr. Domenic Micale
1400 Providence Highway, Bldg. 2
Norwood, MA 02062

Dear Domenic:

This letter will evidence the terms of an amended retention bonus arrangement
between you and UroMed Corporation ("UroMed"). This letter amends and restates
the prior retention bonus arrangement set forth in the letter agreement between
you and UroMed dated February 8, 2000.

UroMed agrees that if you are an employee of the Company on February 28/th/ 2002
(the "Retention Date"), UroMed will pay you a cash bonus in the amount of
$40,000 (the "Retention Bonus"). In the event that prior to the Retention Date
your employment is terminated for death or disability (as defined below), UroMed
will pay you or your estate a pro rata portion of the Retention Bonus based on
                              --- ----
the time elapsed between February 8, 2000 and the Retention Date.

In addition, if your employment is terminated by UroMed prior to the Retention
Date, UroMed may at its discretion, elect to pay you all or a part of the
Retention Bonus. The payment of the Retention Bonus will be entirely within
UroMed's discretion, and will depend on, among other things, the circumstances
underlying the termination, the subjective evaluation by UroMed's Chief
Executive Officer of your job performance, and your willingness to enter into a
separation agreement relating to a transitional role.

You acknowledge that if your employment terminates for any reason other than
death or disability prior to the Retention Date, including a termination by
UroMed for any reason or no reason at all, you will not be entitled to receive
any portion of the Retention Bonus. In addition, this letter is not intended to
imply that you are anything else other than an "at will" employee of UroMed.

For purposes of the letter "disability" is the same as that defined in your
UroMed Long Term Disability Policy.

Any payment of the Retention Bonus will be subject to applicable withholding.
This letter may not be amended or modified except by a writing signed by both of
us. This letter expresses our entire understanding regarding the Retention Bonus
and supersedes all prior discussions, understanding, or agreements, written or
oral, regarding the Retention Bonus, including the February 8, 2000 letter
referred to above.

Please sign where indicated below to confirm our agreement.

Sincerely yours,

UROMED CORPORATION

By: /s/ Dan Muscatello
    ----------------------
Name:   Dan Muscatello
Title:  President and CEO

Agreement Confirmed:

/s/ Domenic C. Micale
--------------------------
Name:  Domenic C. Micale<PAGE>

                                                                   Exhibit 10.33

                        AMENDMENT TO EMPLOYMENT AGREEMENT

     Whereas UroMed Corporation, a Massachusetts corporation with its principal
place of business at 1400 Providence Highway, Building #2, Norwood,
Massachusetts 02062 ("the Company") and Daniel Muscatello an individual residing
at [ ] ("Employee") are parties to an Employment agreement dated on February 4,
1997 and amended on December 1, 1999.

Both parties agree to amend paragraph 2(a) to read:

"Employee's" annual compensation shall be $250,000 ("the Base Salary"). Employee
shall be paid on the 15/th/ day and the last day of each calendar month for the
current month's employment. Pay shall be adjusted pro rata for any partial week
of employment and standard employer deductions shall be made from each payment.
Employee's gross semi-monthly compensation shall be subjected to an annual
review and adjustment.

IN WITNESS WHEREOF the parties hereto have affixed their hands and seals upon
two (2) counterpart originals hereof as of March 12, 2001.

EMPLOYEE                                              UROMED CORPORATION

/s/ Daniel Muscatello                              By /s/ Richard Sandberg
---------------------                                 ----------------------
                                                      its Chairman of the
                                                      Compensation Committee,
                                                      hereunto duly Authorized,
                                                      acting in such capacity,
                                                      and not individually<PAGE>

                                                                   Exhibit 10.34

                        AMENDMENT TO EMPLOYMENT AGREEMENT

     Whereas UroMed Corporation, a Massachusetts corporation with its principal
place of business at 1400 Providence Highway, Building #2, Norwood,
Massachusetts 02062 ("the Company") and Daniel Muscatello an individual residing
at [  ] ("Employee") are parties to an Employment Agreement dated on February 4,
1997, amended on December 1, 1999 and on March 12, 2001

       Whereas both parties seek to continue the employment relationship on
terms and conditions acceptable to each;

   NOW, THEREFORE, in consideration of the foregoing and of the mutual
promises and covenants contained herein, Employee and the Company hereby agree
as follows:

1. Amend paragraph 2(a) of the aforementioned Employment agreement by striking
it in its entirety and replacing it with the following:

"Employee's annual compensation shall be $295,000.00 ("the Base Salary")
effective as of January 1, 2002. Employee shall be paid on the 15/th/ day and
the last day of each calendar month for the current month's employment. Pay
shall be adjusted pro rata for any partial week of employment and standard
employer deductions shall be made from each payment. Employee's gross
semi-monthly compensation shall be subjected to an annual review and
adjustment."

Both parties agree to add a new paragraph 2(d) of the aforementioned Employment
Agreement

2. Add paragraph 2(d) which should read in its entirety:

"Upon signing an amendment to this Employment Agreement during January, 2002,
the Employee shall immediately be paid a one-time signing bonus in the amount of
$85,000."

3. Amend paragraph 4 of the aforementioned Employment agreement by striking it
in its entirety and replacing it with the following:

"Term. As an at-will employee, Employee understands that this agreement and the
employment hereunder may be terminated by either party hereto at any time with
or without cause. If not terminated, this agreement shall cover the terms of the
Employee's employment for a period ending on December 31, 2002. At such time,
the term of this agreement with automatically be extended for an additional one
year unless either the Employee or the Company provides notice of non-renewal
before September 30 2002. The term of this arrangement is referred to as the
"Term". The Term of this Agreement shall not affect the covenants herein that
are intended to survive the Term. Annual salary adjustments pursuant to section
2 above shall not affect the other terms and conditions hereof nor shall it
necessitate any written modifications hereof."

       IN WITNESS WHEREOF the parties hereto have affixed their hands and seals
upon two (2) counterpart originals hereof as of January 23, 2002.

EMPLOYEE                               UROMED CORPORATION

/s/ Daniel Muscatello                  By /s/ Richard Sandberg
---------------------                     --------------------------------------
                                          Chairman of the Compensation Committee

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