Document:

EX 10.42

 Exhibit 10.42 
 THIRD AMENDED AND RESTATED 
 UNSECURED REVOLVING 

DEMAND PROMISSORY NOTE 
  

			
	$40,000,000.00	  	December 31, 2012

 Section 1. Promise to Pay. For and in consideration of value
received, the undersigned, NL INDUSTRIES, INC., a corporation duly organized under the laws of the state of New Jersey ( “Borrower”), promises to pay, in lawful money of the United States of America, to
the order of VALHI, INC., a corporation duly organized under the laws of the state of Delaware (“Valhi”), or the holder hereof (as applicable, Valhi or such holder shall be referred to as
“Noteholder”), the principal sum of FORTY MILLION and NO/100ths United States Dollars ($40,000,000.00) or such lesser amount as shall equal the unpaid principal amount of the loan made by Noteholder to Borrower together with
interest on the unpaid principal balance from time to time pursuant to the terms of this Third Amended and Restated Unsecured Revolving Demand Promissory Note, as it may be amended from time to time (this “Note”). This Note shall be
unsecured and will bear interest on the terms set forth in Section 7 below. Capitalized terms not otherwise defined shall have the meanings given to such terms in Section 17 of this Note. 

Section 2. Amendment and Restatement. This Note renews, replaces, amends and restates
in its entirety the Second Amended and Restated Unsecured Revolving Demand Promissory Note dated December 13, 2011 in the original principal amount of $40,000,000.00 payable to the order of Noteholder and executed by Borrower (the
“Second Amended Note”). The Second Amended Note replaced, amended and restated in its entirety the First Amended and Restated Unsecured Revolving Demand Promissory Note dated December 31, 2010 in the original
principal amount of $40,000,000.00 payable to the order of Noteholder and executed by Borrower (the “First Amended Note”). The First Amended Note replaced, amended and restated in its entirety the Unsecured Revolving
Demand Promissory Note dated June 23, 2010 in the original principal amount of $40,000,000.00 payable to the order of Noteholder and executed by Borrower (the “Original Note”). This Note amends and restates in its
entirety the Second Amended Note, the First Amended Note and the Original Note (collectively, the “Prior Notes”); provided that such amendment and restatement shall operate to renew, amend and
modify the rights and obligations of the parties under each Prior Note, as provided herein, but shall not extinguish the obligations under each Prior Note, nor effect a novation thereof. As of the close of business on December 31, 2012, the
unpaid principal balance of the Second Amended Note was nil and the accrued and unpaid interest thereon was nil, which are the principal and accrued and unpaid interest owed under this Note as of the close of business on the date of this Note.

 Section 3. Place of Payment. All payments will be made at
Noteholder’s address at Three Lincoln Centre 5430 LBJ Freeway, Suite 1700, Dallas, Texas 75240-2697, Attention: Treasurer, or such other place as Noteholder may from time to time appoint in writing. 

Section 4. Payments. The unpaid principal balance of this Note and any unpaid and accrued
interest thereon shall be due and payable on the Final Payment Date. Prior to the Final Payment Date, any unpaid and accrued interest on an unpaid principal balance shall be paid in arrears quarterly on the last day of each March, June, September
and December, commencing March 31, 2013. All payments on this Note shall be applied first to accrued and unpaid interest, next to accrued interest not yet payable and then to principal. If any payment of principal or interest on this Note shall
become due on a day that is not a Business Day, such payment shall be made on the next succeeding Business Day and the payment shall be the amount owed on the original payment date. 

Section 5. Prepayments. This Note may be prepaid in part or in full at any time without
penalty. 
 Section 6. Borrowings. Prior to the Final Payment Date, Noteholder
expressly authorizes Borrower to borrow, repay and re-borrow principal under this Note in increments of $100,000 on a daily basis so long as: 
  

	 	•	the aggregate outstanding principal balance does not exceed $40,000,000.00; and 

 

	 	•	no Event of Default has occurred and is continuing. 

 Notwithstanding anything else in this Note, in no event will Noteholder be required to lend money to Borrower under this Note and loans under this Note shall be at the sole and absolute discretion of
Noteholder. 

  
 Page 1 of 4.

 Section 7. Interest. The unpaid principal
balance of this Note shall bear interest at the rate per annum of the Prime Rate plus two and three-quarters percent (2.75%). In the event that an Event of Default occurs and is continuing, the unpaid principal amount shall bear interest from the
Event of Default at the rate per annum of the Prime Rate plus four percent (4.00%) until such time as the Event of Default is cured. Accrued interest on the unpaid principal of this Note shall be computed on the basis of a 365- or 366-day year
for actual days (including the first, but excluding the last day) elapsed, but in no event shall such computation result in an amount of accrued interest that would exceed accrued interest on the unpaid principal balance during the same period at
the Maximum Rate. Notwithstanding anything to the contrary, this Note is expressly limited so that in no contingency or event whatsoever shall the amount paid or agreed to be paid to Noteholder exceed the Maximum Rate. If, from any circumstances
whatsoever, Noteholder shall ever receive as interest an amount that would exceed the Maximum Rate, such amount that would be excessive interest shall be applied to the reduction of the unpaid principal balance and not to the payment of interest,
and if the principal amount of this Note is paid in full, any remaining excess shall be paid to Borrower, and in such event, Noteholder shall not be subject to any penalties provided by any laws for contracting for, charging, taking, reserving or
receiving interest in excess of the highest lawful rate permissible under applicable law. All sums paid or agreed to be paid to Noteholder for the use, forbearance or detention of the indebtedness of Borrower to Noteholder shall, to the extent
permitted by applicable law, be amortized, prorated, allocated and spread throughout the full term of such indebtedness until payment in full of the principal (including the period of any renewal or extension thereof) so that the interest on account
of such indebtedness shall not exceed the Maximum Rate. If at any time the Contract Rate is limited to the Maximum Rate, any subsequent reductions in the Contract Rate shall not reduce the rate of interest on this Note below the Maximum Rate until
the total amount of interest accrued equals the amount of interest that would have accrued if the Contract Rate had at all times been in effect. In the event that, upon the Final Payment Date, the total amount of interest paid or accrued on this
Note is less than the amount of interest that would have accrued if the Contract Rate had at all times been in effect with respect thereto, then at such time, to the extent permitted by law, in addition to the principal and any other amounts
Borrower owes to the Noteholder, the Borrower shall pay to the Noteholder an amount equal to the difference between: (i) the lesser of the amount of interest that would have accrued if the Contract Rate had at all times been in effect or the
amount of interest that would have accrued if the Maximum Rate had at all times been in effect; and (ii) the amount of interest actually paid on this Note. 
 Section 8. Remedy. Upon the occurrence and during the continuation of an Event of Default, Noteholder shall have all of the rights and remedies provided in the
applicable Uniform Commercial Code, this Note or any other agreement with Borrower and in favor of Noteholder, as well as those rights and remedies provided by any other applicable law, rule or regulation. In conjunction with and in addition to the
foregoing rights and remedies of Noteholder, Noteholder may declare all indebtedness due under this Note, although otherwise unmatured, to be due and payable immediately without notice or demand whatsoever. All rights and remedies of Noteholder are
cumulative and may be exercised singly or concurrently. The failure to exercise any right or remedy will not be a waiver of such right or remedy. 
 Section 9. Right of Offset. Noteholder shall have the right of offset against amounts that may be due by Noteholder now or in the future to Borrower against
amounts due under this Note. 
 Section 10. Record of Outstanding Indebtedness. The
date and amount of each repayment of principal outstanding under this Note or interest thereon shall be recorded by Noteholder in its records. The principal balance outstanding and all accrued or accruing interest owed under this Note as recorded by
Noteholder in its records shall be the best evidence of the principal balance outstanding and all accrued or accruing interest owed under this Note; provided that the failure of Noteholder to so record or any error in so recording or
computing any such amount owed shall not limit or otherwise affect the obligations of Borrower under this Note to repay the principal balance outstanding and all accrued or accruing interest. 

Section 11. Waiver. Borrower and each surety, endorser, guarantor, and other party now or
subsequently liable for payment of this Note, severally waive demand, presentment for payment, notice of nonpayment, notice of dishonor, protest, notice of protest, notice of the intention to accelerate, notice of acceleration, diligence in
collecting or bringing suit against any party liable on this Note, and further agree to any and all extensions, renewals, modifications, partial payments, substitutions of evidence of indebtedness, and the taking or release of any collateral with or
without notice before or after demand by Noteholder for payment under this Note. 

  
 Page 2 of 4.

 Section 12. Costs and Attorneys’ Fees. In
addition to any other amounts payable to Noteholder pursuant to the terms of this Note, in the event Noteholder incurs costs in collecting on this Note, this Note is placed in the hands of any attorney for collection, suit is filed on this Note or
if proceedings are had in bankruptcy, receivership, reorganization, or other legal or judicial proceedings for the collection of this Note, Borrower and any guarantor jointly and severally agree to pay on demand to Noteholder all expenses and costs
of collection, including, but not limited to, reasonable attorneys’ fees incurred in connection with any such collection, suit, or proceeding, in addition to the principal and interest then due. 

Section 13. Time of Essence. Time is of the essence with respect to all of Borrower’s
obligations and agreements under this Note. 
 Section 14. Jurisdiction and
Venue. THIS NOTE SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE DOMESTIC LAWS OF THE STATE OF TEXAS, WITHOUT GIVING EFFECT TO ANY CHOICE OF LAW OR CONFLICT OF LAW PROVISION OR RULE (WHETHER OF THE STATE OF TEXAS OR ANY OTHER
JURISDICTION) THAT WOULD CAUSE THE APPLICATION OF THE LAWS OF ANY JURISDICTION OTHER THAN THE STATE OF TEXAS. BORROWER CONSENTS TO JURISDICTION IN THE COURTS LOCATED IN DALLAS, TEXAS. 

Section 15. Notice. Any notice or demand required by this Note shall be deemed to have been
given and received on the earlier of (i) when the notice or demand is actually received by the recipient or (ii) 72 hours after the notice is deposited in the United States mail, certified or registered, with postage prepaid,
and addressed to the recipient. The address for giving notice or demand under this Note (i) to Noteholder shall be the place of payment specified in Section 3 or such other place as Noteholder may specify in writing to
Borrower and (ii) to Borrower shall be the address below Borrower’s signature or such other place as Borrower may specify in writing to Noteholder. 
 Section 16. Successors and Assigns. All of the covenants, obligations, promises and agreements contained in this Note made by Borrower shall be binding upon
its successors and permitted assigns, as applicable. Notwithstanding the foregoing, Borrower shall not assign this Note or its performance under this Note without the prior written consent of Noteholder. 

Section 17. Definitions. For purposes of this Note, the following terms shall have the
following meanings: 
 (a) “Business Day” shall mean any day banks are open in the
state of Texas. 
 (b) “Contract Rate” means the amount of any interest (including
fees, charges or expenses or any other amounts that, under applicable law, are deemed interest) contracted for, charged or received by or for the account of Noteholder. 

(c) “Event of Default” wherever used herein, means any one of the following events:

 (i) Borrower fails to pay any amount due on this Note and/or any fees or sums due under or in
connection with this Note after any such payment otherwise becomes due and payable and three Business Days after demand for such payment; 
 (ii) Borrower otherwise fails to perform or observe any other provision contained in this Note and such breach or failure to perform shall continue for a period of thirty days after notice thereof
shall have been given to Borrower by Noteholder; 
 (iii) a case shall be commenced against Borrower, or
Borrower shall file a petition commencing a case, under any provision of the Federal Bankruptcy Code of 1978, as amended, or shall seek relief under any provision of any other bankruptcy, reorganization, arrangement, insolvency, readjustment of
debt, dissolution or liquidation law of any jurisdiction, whether now or hereafter in effect, or shall consent to the filing of any petition against it under such law, or Borrower shall make an assignment for the benefit of its creditors, or shall
admit in writing its inability to pay its debts generally as they become due, or shall consent to the appointment of a receiver, trustee or liquidator of Borrower or all or any part of its property; or 

  
 Page 3 of 4.

 (iv) an event occurs that, with notice or lapse of time, or both,
would become any of the foregoing Events of Default. 
 (d) “Final Payment Date”
shall mean the earlier of: 
  

	 	•	written demand by Noteholder for payment of all or part of the principal and interest accrued and unpaid thereon, but in any event no earlier than March 31, 2014;

  

	 	•	December 31, 2014; or 

  

	 	•	acceleration as provided herein. 

 (e) “Maximum Rate” shall mean the highest lawful rate permissible under applicable law for the use, forbearance or detention of money. 

(f) “Prime Rate” shall mean the fluctuating interest rate per annum in effect from time to
time equal to the base rate on corporate loans as reported as the Prime Rate in the Money Rates column of The Wall Street Journal or other reliable source. 

 

			
	 BORROWER:
  

NL INDUSTRIES, INC.

		
	By:	 	 
		 	John A. St. Wrba, Vice President and Treasurer
	
	Address:
	
	 5430 LBJ Freeway, Suite 1700
 Dallas, Texas 75240-2697

 As of the date hereof, Valhi, Inc., as Noteholder, hereby agrees that this Note renews and
replaces, amends and restates in its entirety each Prior Note (but shall not extinguish the obligations under each Prior Note, nor effect a novation thereof) and that the unpaid principal of nil and the accrued and unpaid interest thereon of nil
that was owed under the Second Amended Note as of the close of business on December 31, 2012 are the unpaid principal and the accrued and unpaid interest thereon, respectively, owed under this Note as of the close of business on the date of
this Note. 
  

			
	VALHI, INC.
		
	By:	 	 
		 	Gregory M. Swalwell
		 	Vice President and Controller

  
 Page 4 of 4.EX-10.31

 Exhibit 10.31 
 FIRST AMENDMENT OF LEASE 
 THIS FIRST AMENDMENT OF LEASE (the
“First Amendment”) is made this 17th day of September, 2012 by and between RB KENDALL FEE, LLC, a Delaware limited liability company (“Landlord”) and IN VIVO THERAPEUTICS CORPORATION, a Delaware
corporation (“Tenant”). 
 BACKGROUND: 

A. Reference is made to a certain Lease Agreement dated November 29, 2011 by and between Landlord and Tenant, demising approximately
20,917 rentable square feet of space on the fourth (4th) floor of Building 1400 (the “Existing Premises”) in One Kendall Square, Cambridge, Massachusetts (the “Complex”). Capitalized terms used but not defined
herein shall have the same meaning as in the Lease. 
 B. Landlord and Tenant are the current holders, respectively, of the
lessor’s and lessee’s interests in the Lease. 
 C. Landlord and Tenant desire to expand the Existing Premises to
include additional space within Building 1400 in the Complex and to further amend the Lease, all as set forth herein. 

AGREEMENTS: 
 NOW, THEREFORE, in consideration of the mutual covenants and agreements herein contained, and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged,
Landlord and Tenant hereby agree and amend the Lease as follows: 
  

	 	1.	Expansion Space and Additional Space. 

 (a) Effective upon the later of the date that (i) this Amendment has been executed and delivered by Landlord and Tenant and approved in writing by Landlord’s mortgagee, and (ii) Landlord
delivers exclusive possession of the Expansion Space (hereinafter defined) to Tenant in the Delivery Condition (the “Expansion Commencement Date”), approximately 5,233 rentable square feet of space on the fourth (4th) floor of
Building 1400 identified on the plan attached hereto as Exhibit 1 as the Expansion Space (the “Expansion Space”) shall be deemed added to and incorporated into the Existing Premises, whereupon the Total Rentable Area of the
Premises shall be increased to 26,150 square feet. The demise and use of the Expansion Space shall be upon and subject to all of the terms and conditions of the Lease, except as expressly set forth in this First Amendment. Tenant acknowledges and
agrees that the Expansion Space may be used for general office purposes only and not for any laboratory or chemical storage uses. All references to the Premises in the Lease shall include the Expansion Space and all references to Exhibit 2 in
the Lease shall be deemed to include and refer to Exhibit 1 attached hereto, as applicable. The Expansion Space shall be delivered in broom clean condition, free of all occupants, personal property, trade fixtures and equipment (with the
exception of the Remaining Furniture, Fixtures and Equipment hereinafter defined), and with all Building systems serving the Expansion Space in good working condition, with new flooring and ceiling tiles (using Building standard materials) installed
in the common area corridor leading to the Expansion Space and new paint on the radiator in said corridor (using Building standard colors) (collectively, the “Delivery Condition”), and, shall otherwise be accepted by Tenant in
“as-is”, “where-is” condition without any warranty of fitness for use or occupancy, expressed or implied, except as otherwise expressly set forth herein or in the Lease. Tenant agrees that 

  
 1 

 
Landlord has no work to perform in or on the Expansion Space to prepare same for Tenant’s use and occupancy except as set forth in this First Amendment. The foregoing shall in no way
derogate from Landlord’s ongoing repair and maintenance obligation as may be set forth in the Lease. 
 (b) Effective upon
the Expansion Commencement Date, the former common hallways and bathroom shown on the plan attached hereto as Exhibit 1A (the “Additional Space”) shall be considered be deemed added to and incorporated into the Existing
Premises. All references to the Premises in the Lease shall include the Additional Space and all references to Exhibit 2 in the Lease shall be deemed to include and refer to Exhibit 1A attached hereto, as applicable. Landlord shall
cause the Additional Space to be cleaned on Monday through Friday (excepting Massachusetts or City of Cambridge legal holidays) in a manner consistent with cleaning standards generally prevailing in comparable buildings. 

(c) The “Expansion Space Rent Commencement Date” shall be the later to occur of November 1, 2012 and the Expansion
Space Commencement Date. Prior to the Expansion Space Rent Commencement Date Tenant shall continue to pay Yearly Rent, and or other amounts payable under the Lease, for the Existing Premises in the amounts provided for in the Lease as of the date
hereof and as amended herein. 
 2. Term. The term of the Lease with respect to the Existing Premises commenced on
July 12, 2012. The term of the Lease with respect to the Expansion Space and the Additional Space shall commence on the Expansion Commencement Date and thereafter shall be co-terminous with the term of the Lease, expiring on October 31,
2018, unless the Lease is otherwise terminated or extended pursuant to the terms and conditions of the Lease. 
 3. Yearly
Rent. Commencing on the Expansion Space Rent Commencement Date, the Yearly Rent due under the Lease with respect to the Expansion Space shall be as follows: 
  

													
	 Period
	  	Yearly Rent	 	  	Monthly
Rent	 	  	Rent Per
Rentable
Square Foot	 
	 Expansion Space Rent Commencement Date – October 31, 2013
	  	$	198,854.00	  	  	$	16,571.17	  	  	$	38.00	  
	 November 1, 2013 – October 31, 2014
	  	$	204,087.00	  	  	$	17,007.25	  	  	$	39.00	  
	 November 1, 2014 – October 31, 2015
	  	$	225,908.61	  	  	$	18,825.72	  	  	$	43.17	  
	 November 1, 2015 – October 31, 2016
	  	$	231,141.61	  	  	$	19,261.80	  	  	$	44.17	  
	 November 1, 2016 – October 31, 2017
	  	$	236,374.61	  	  	$	19,697.88	  	  	$	45.17	  
	 November 1, 2017 – October 31, 2018
	  	$	241,607.61	  	  	$	20,133.97	  	  	$	46.17	  

  
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 The Yearly Rent for the entire Premises, including the Expansion Space, shall be payable in accordance with
the terms of the Lease and shall be in addition to all other amounts due and payable by Tenant pursuant to the Lease. 
 4.
Escalation. (a) In addition to payment of the Tax Share in connection with the Existing Premises, Tenant shall pay to Landlord with regard to the Expansion Space, with respect to any fiscal period in respect of which Taxes are due and
payable during the term of the Lease (the “Tax Period”), the sum of: (x) 4.05% (the “Tenant’s Expansion Proportionate Building Share”) of the amount (if any) by which Building Taxes for such Tax Period
exceeds the Building Taxes in Fiscal Year 2014 (the “Real Estate Tax Base Year”) (the “Building Tax Base”), plus (y) 0.82% (the “Tenant’s Expansion Proportionate Common Share”) of the
amount (if any) by which Common Area Taxes for such Tax Period exceeds the Common Area Taxes in the Real Estate Tax Base Year (the “Common Area Tax Base”), such sum being hereinafter referred to as “Tax Excess”.
Tenant’s obligation to pay the Tax Excess hereunder shall commence on July 1, 2014. Taxes in respect of the Expansion Space shall be calculated in the manner set forth in the Lease. In implementation and not in limitation of the foregoing,
Tenant shall remit to Landlord pro rata monthly installments on account of projected Tax Excess, calculated by Landlord on the basis of the most recent Tax data or budget available. If the total of such monthly remittances on account of any Tax
Period is greater than the actual Tax Excess for such Tax Period, Landlord shall credit the difference against the next installment of rent or other charges due to Landlord under the Lease, or if the term has expired, Landlord shall promptly repay
such excess to Tenant. If the total of such remittances is less than the actual Tax Excess for such Tax Period, Tenant shall pay the difference to Landlord within thirty (30) days of when billed therefor. Appropriate credit against Tax
Excess shall be given for any refund obtained by reason of a reduction in any Taxes by the Assessors or the administrative, judicial or other governmental agency responsible therefor. The original computations, as well as reimbursement or payments
of additional charges, if any, or allowances, if any, under the provisions of this paragraph shall be based on the original assessed valuations with adjustments to be made at a later date when the tax refund, if any, shall be paid to Landlord by the
taxing authorities. Expenditures for reasonable legal fees and for other similar or dissimilar expenses incurred in obtaining the tax refund may be charged against the tax refund before the adjustments are made for the Tax Period. 

(b) In addition to payment of the Operating Expense Share in connection with the Existing Premises, Tenant shall pay to Landlord with
regard to the Expansion Space, with respect to any Operating Year, the sum of: (x) 4.05% (the “Tenant’s Expansion Proportionate Building Share”) of the amount (if any) by which Building Operating Costs for such Operating
Year exceeds Building Operating Costs in the calendar year 2013 (the “Operating Costs Base Year”), plus (y) 0.82% (the “Tenant’s Expansion Proportionate Common Share” of the amount (if any) by which Common
Area Operating Costs for such Operating Year exceeds Common Area Operating Costs in the Operating Costs Base Year, such sum being hereinafter referred to as “Operating Expense Excess”. Tenant’s obligation to pay the Operating
Expense hereunder shall commence on January 1, 2014. Operating Costs in respect of the Expansion Space shall be calculated in the manner set forth in the Lease, and the “gross-up” provision in Section 9.2(f)(6) of the Lease shall
apply, without limitation, to the Operating Cost Base Year. In implementation and not in limitation of the foregoing, Tenant shall remit to Landlord pro rata monthly installments on account of projected Operating Expense Excess, calculated by
Landlord on the basis of the most recent Operating Costs date or budget available. If the total of such monthly remittances on account of any Operating Year is greater than the actual Operating Expense Excess for such Operating Year, Tenant may
credit the different against the next installment of rent or other charges due to Landlord hereunder. If the total of such remittances is less than actual Operating Expense Excess for such Operating Year, Tenant shall pay the difference to Landlord
within thirty (30) days after being billed therefor. 

  
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 5. Utilities. In addition to the Yearly Rent, and other amounts payable under the
Lease, Tenant shall be obligated to pay, when billed by Landlord, for its electricity usage in the Premises, including the Expansion Space, in accordance with the provisions of Section 8.1 of the Lease. 

6. Tenant’s Improvements; Expansion Improvement Allowance. After the date of this First Amendment, Tenant may begin its
Tenant’s leasehold improvements to the Expansion Space (“Tenant’s Improvements”) in the same manner and in accordance with the terms and conditions of the Lease. Prior to commencing work on Tenant’s Improvements,
Tenant’s contractors and subcontractors shall provide Landlord with evidence of builder’s risk, general liability, automobile liability, workers compensation, and excess/umbrella insurance policies in coverages reasonably acceptable to
Landlord, such policies to be maintained throughout the construction of Tenant’s Improvements. In connection with Tenant’s Improvements, Landlord shall reimburse Tenant up to a maximum of Twenty-five and 00/100 Dollars ($25.00) per
rentable square foot of the Expansion Space, not to exceed One Hundred Thirty Thousand Eight Hundred Twenty Five and 00/100 Dollars ($130,825.00) (“Expansion Improvement Allowance”) in the aggregate toward the actual cost (which
cost shall include, without limitation, the costs of construction, the cost of permits and permit expediting, and all architectural and engineering services obtained by Tenant in connection therewith) of Tenant’s Improvements relating to the
Expansion Space that are completed solely during the first six (6) months after the date of this First Amendment. The Expansion Improvement Allowance shall be utilized for so-called “hard” costs and building improvements to the
Expansion Space pursuant to Tenant’s Plans, and for so-called “soft” costs limited to architectural and design costs, permit fees, construction management fees, reasonable moving costs, and legal fees relating to Tenant’s fit-up
of and/or move into the Expansion Space. So long as Tenant is not in default of the Lease beyond any Grace Period, payment of the Expansion Improvement Allowance shall be paid by Landlord to Tenant in one (1) lump sum payment based upon a
request for payment submitted by Tenant upon the completion of Tenant’s Improvements. Such request for payment shall be accompanied by a written certification reasonably satisfactory to Landlord by Tenant’s architect that all work has been
completed, along with any other support documentation reasonably required by Landlord in connection therewith, including lien waivers, provided, however, that the Expansion Improvement Allowance (or a suitable portion thereof) may not be released by
Landlord if any liens, notices of contract or similar instruments relating to Tenant’s Improvements exist or appear in the record title to the Building or Complex. Any and all costs for the construction of the Expansion Space above the
Expansion Improvement Allowance shall be paid by Tenant to the applicable contractors, subcontractors, and material suppliers. In the event of a default under the Lease (or an event which with passage of time or the giving of notice, or both, would
constitute a default) or if a lien has been filed by one of Tenant’s contractors, subcontractors or material suppliers (or in Landlord’s good faith belief the filing of such a lien is likely), Landlord reserves the right to make any
payment (or portion thereof) of the Expansion Improvement Allowance payable jointly to Tenant and its general contractor (or subcontractor or supplier) or directly to such contractor, subcontractor or supplier. Tenant’s Improvements shall be in
conformity with plans and specifications (“Tenant’s Plans”) submitted to and approved by Landlord (such approval not to be unreasonably withheld, delayed or conditioned), and constructed by a contractor approved by Landlord (such
approval not to be unreasonably withheld, delayed or conditioned) in the same manner and in accordance with the terms of the Lease. 
 7. Furniture; Bill of Sale. Landlord and Tenant acknowledge that certain furniture, fixtures and equipment presently located in the Expansion Space shall remain in the Expansion Space upon delivery
of the Expansion Space to Tenant. Landlord hereby agrees to execute and deliver to Tenant a Bill of Sale in the form attached hereto as Exhibit A (the “Bill of Sale”) conveying to Tenant all of Landlord’s right, title
and interest in and to the furniture, fixtures and equipment in the Premises as of the date hereof more particularly described on Schedule 1 to the Bill of Sale (collectively, the “Remaining Furniture, Fixtures and Equipment”).

  
 4 

 8. Extension Payment. As further consideration for this First Amendment, upon the
Expansion Commencement Date, Landlord shall pay to Tenant an amount equal to the Termination Payment made by the prior tenant of the Expansion Space, which Landlord represents to be $43,259.47. 

9. Additional Security Deposit. Upon the execution of this First Amendment by Tenant, Tenant shall deliver to Landlord an
amendment to the existing Letter of Credit (in the current amount of $294,662.00) being held by the Landlord under the Lease increasing the amount under the Letter of Credit by $16,571.17 for a total Letter of Credit amount of $311,233.17 or deliver
a Substitute Letter of Credit (as defined in Section 29.13 of the Lease) in an amount equal to $311,233.17 representing the combined security amount required under the Lease and this First Amendment. The foregoing shall not derogate from
Tenant’s ongoing right to reduce the amount of the Letter of Credit under Section 29.13 of the Lease, and any future 25% reductions shall be applied to the amount of the Letter of Credit as increased hereby. 

10. Parking. Effective upon the date of this First Amendment, Tenant shall be entitled to a total of six (6) additional
monthly parking passes (for a total of twenty seven (27)) available to Tenant for use in the One Kendall Square Garage pursuant to, and in accordance with, Section 29.14 of the Lease, except that, as of the date of this First Amendment,
Landlord represents that the current prevailing rate for such passes is $225.00 per month, which rate may vary from time to time. 
 11. Amendment re Subleasing and Assignments. The last sentence of Section 16.1 is amended to read as follows: “Tenant shall not collaterally assign this Lease (or any portion thereof) or
permit any assignment of this Lease by mortgage, other encumbrance or operation of law, without, in each instance, having first received the express, written consent of Landlord and provided Landlord has approved the form of such assignment, which
consent and approval shall not be unreasonably withheld, conditioned or delayed.” 
 12. Brokers. Landlord and
Tenant each warrant and represent to the other that they have dealt with no brokers in connection with the negotiation or consummation of this First Amendment other than Beal and Company, Inc. and CBRE NE (collectively, the
“Brokers”) and in the event of any brokerage claim against either party by any person claiming to have dealt with either Landlord or Tenant in connection with this First Amendment, other than the Brokers, the party with whom such
person claims to have dealt shall defend and indemnify the other party against such claim. Landlord shall pay any commission due the Brokers pursuant to a separate agreement. 
 13. Consent and Reaffirmation of Guarantor. The undersigned Guarantor acknowledges and consents to this First Amendment and confirms that its Guaranty dated November 30, 2011, remains
in full force and effect and continues to guaranty the Lease as amended herein. 
 14. Reaffirmation. In all other
respects the Lease shall remain unmodified and shall continue in full force and effect, as amended hereby. The parties hereby ratify, confirm, and reaffirm all of the terms and conditions of the Lease, as amended hereby. 

15. Counterparts. This First Amendment may be signed in any number of counterparts, each of which so executed shall be deemed
original and such counterparts shall together constitute the First Amendment. Facsimile signatures shall be sufficient and binding. 

  
 5 

 IN WITNESS WHEREOF the parties hereto have executed this First Amendment of Lease on the
date first written above in multiple copies, each to be considered an original hereof, as a sealed instrument. 
  

									
	 LANDLORD:
  

RB KENDALL FEE, LLC
	 		 	 TENANT:
  

IN VIVO THERAPEUTICS CORPORATION

					
	By:	 	/s/ Robert L. Beal	 		 	By:	 	/s/ Frank Reynolds
		 	Robert L. Beal, its authorized signatory	 		 		 	 Frank Reynolds
 Chief
Executive Officer

  

			
	 GUARANTOR:
  

IN VIVO THERAPEUTICS HOLDING

CORPORATION

		
	By:	 	/s/ Frank Reynolds
		 	 Frank Reynolds
 Chief
Executive Officer

  
 6 

 EXHIBIT 1 
 PLAN FOR EXPANSION SPACE 
  
 

 

  
 7 

 EXHIBIT 1A 
 PLAN FOR ADDITIONAL SPACE 
  
 

 

  
 8 

 EXHIBIT A 
 BILL OF SALE 
 By this instrument dated as of
September 17, 2012, for good and valuable consideration, the receipt of which is hereby acknowledged, RB KENDALL FEE, LLC, a Delaware limited liability company, having a mailing address c/o The Beal Companies, LLP, 177 Milk Street,
Boston, Massachusetts (“Transferor”) does hereby grant, bargain, transfer, assign, sell and convey unto IN VIVO THERAPEUTICS CORPORATION, a Delaware corporation, having a mailing address of One Kendall Square, Building 1400,
4th Floor, Cambridge, Massachusetts (the
“Transferee”) all of the furniture, fixtures and equipment (the “Remaining Furniture, Fixtures and Equipment”) more particularly described on Schedule 1 attached hereto and located in, on or at the premises located on the fourth
(4th) floor of Building 1400 at One Kendall Square,
Cambridge, Massachusetts, as described in the First Amendment of Lease of even date herewith (the “First Amendment”). 

Transferor hereby warrants that it is the lawful owner of the Remaining Furniture, Fixtures and Equipment described above and has good
right to sell the same to Transferee. 
 Subject to the foregoing, Transferee acknowledges and agrees that the Remaining
Furniture, Fixtures and Equipment is hereby transferred to Transferee in its “as is” condition with all faults and with no representations or warranties of any kind except as specifically set forth herein, any warranty of merchantability
or fitness is hereby expressly excluded. This instrument and all of its terms shall inure to the benefit of and be binding upon the undersigned and its successors and assigns. 
 EXECUTED as a sealed instrument as of the date written above. 
  

			
	 TRANSFEROR:

RB KENDALL FEE, LLC, a Delaware limited liability company

		
	By:	 	 
		 	Robert L. Beal, its Authorized Signatory

  

			
	 TRANSFEREE:

IN VIVO THERAPEUTICS CORPORATION, a Delaware corporation

		
	By:	 	 
		 	 Frank Reynolds
 Chief
Executive Officer

  
 9 

 Schedule 1 
 9 office work stations 
 16 cubicle office work stations 

2 conference tables 
 Approximately 20
miscellaneous office/visitor chairs 

  
 10

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