Document:

exv4w5

	 	 	 	 	 

Exhibit 4.5

AMENDMENT NO. 3

TO THE

GLAXOSMITHKLINE RETIREMENT SAVINGS PLAN

(Amended and Restated Effective July 1, 2001, as

Amended Through November 26, 2002)

 

          Pursuant to resolutions of the Board of Directors of SmithKline Beecham Corporation, adopted
June 15, 2009, the GlaxoSmithKline Retirement Savings Plan (the “Plan”) is amended as follows:

     1. Article 1 of the Plan is amended by adding the definition of “Corporate Transaction” to
read as follows:

“‘Corporate Transaction’ means a transaction pursuant to which the
Company or an Affiliated Company (i) acquires an ownership interest in an
employer such that such employer becomes an Affiliated Company, or (ii)
acquires substantially all of the assets of a trade or business of an
employer, as a result of which former employees of such employer become
Employees.”

     2. Article 2 of the Plan is amended by adding a Section 2.2.4 to read as follows:

“2.2.4 Corporate Transactions. Except as otherwise provided in
this Section 2.2.4, an individual who becomes an Employee as the direct
result of a Corporate Transaction shall not be treated as an Employee
before he is first credited with an Hour of Service. An employee of an
acquired company listed in Appendix C who became an Employee as the direct
result of a Corporate Transaction, and who subsequently became an Eligible
Employee as of the relevant eligibility service effective date listed in
Appendix C for such acquired company, shall be credited with a Period of
Service for purposes of Section 2.2.2.1(C) and Section 4.1.4 based on an
Employment Commencement Date determined as of his employment commencement
date with the acquired company.”

     3. The Plan is amended by adding an Appendix C in substantially the form attached hereto.

Executed this 22nd day of June, 2009.

	 	 	 	 	 
	 	SMITHKLINE BEECHAM CORPORATION,

a GlaxoSmithKline company

 	 
	 	By:  	/s/ William J. Mosher
 	 
	 	 	William J. Mosher 	 
	 	 	Vice President and Secretary 	 

 

 

	 	 	 	 	 

APPENDIX C

ACQUISITION TABLE

Pursuant to Section 2.2.4, an Employee shall be credited with a Period of Service for purposes of
Section 2.2.2.1(C) and Section 4.1.4 with an Employment Commencement Date determined based on his
employment commencement date with one of the acquired companies listed below, provided he is an
Eligible Employee of a Participating Company on the relevant Eligibility Service Effective Date:

	 	 	 
	Acquired Company	 	Eligibility Service Effective Date
	Corixa Corporation

	 	January 1, 2006
	ID Biomedical Corporation of Maryland

	 	June 26, 2006
	ID Biomedical Corporation of Northborough

	 	June 26, 2006
	CNS, Inc.

	 	January 22, 2007
	Praecis Pharmaceuticals Incorporated

	 	April 30, 2007
	Reliant Pharmaceuticals, Inc.

	 	February 18, 2008
	Sirtris Pharmaceuticals, Inc.

	 	July 3, 2008
	Genelabs Technology, Inc.

	 	February 9, 2009exv4w7

Exhibit 4.7

AMENDMENT NO. 1

TO THE

GSK PUERTO RICO RETIREMENT SAVINGS PLAN

(Amended and Restated Effective July 1, 2001)

 

     Pursuant to resolutions of the Board of Directors of SB Pharmco Puerto Rico Inc., adopted
December 14, 2007, the GSK Puerto Rico Retirement Savings Plan (the “Plan”) is hereby amended as
follows effective January 1, 2007, unless otherwise noted:

     1. Section 4.5.2 of the Plan is hereby restated in its entirely to read as follows:

“4.5.2 Participants Right to Diversify. A Participant or beneficiary may transfer
all or a portion of the value of his Stock Ownership Account to another Investment Fund
effective as of such date determined by the Plan Administrator. Any portion of the Stock
Ownership Account that the Participant or beneficiary does not elect to diversify his
investments shall be invested in the Employer Stock Fund. The Plan Administrator shall
establish reasonable non-discriminatory rules to implement and administer the provisions of
this Section 4.5.2, such rules which shall designate reasonable periods of time (which shall
occur no less frequently than quarterly) during which a Participant or beneficiary may
diversify his Stock Ownership Account.”

     2. Section 7.1 of the Plan is hereby restated in its entirety to read as follows:

“7.1 Participant Contributions Account. Until such time as the Plan Administrator
may direct otherwise or unless specifically restricted for particular Investment Funds, each
Participant may direct the Plan Administrator in the manner and pursuant to the rules
established by the Plan Administrator and under this Section 7.1, to invest the
Participant’s Account, including the Participant’s Stock Ownership Account, subject to the
provisions of Section 4.5.2. Investment managers may be appointed by the Plan Administrator
to advise the Trustee regarding investments of all or a portion of the Trust Fund assets and
to direct the investment of those assets.

     7.1.1 All investment directions shall be made in the manner and pursuant to the uniform
rules and procedures established by the Plan Administrator.

     7.1.2 Until a new investment direction is given to the Plan Administrator in the manner
specified by the Plan Administrator, investment of contributions to a Participant’s Account
shall be governed by the investment direction last given by the Participant in accordance
with the Plan rules.

     7.1.3 To the extent permissible by law, no fiduciary (within the meaning given in
Section 3(21)(A) of ERISA) shall be liable for any loss which results from a Participant’s
exercise or failure to exercise his investment election.”

 

 

     3. Section 7.2 of the Plan is hereby restated in its entirety to read as follows:

“7.2 Transfers Between Investment Funds. By providing prior written or telephone
notice, subject to such rules as the Plan Administrator may prescribe from time to time, a
Participant may transfer, effective as of such date determined by the Plan Administrator,
such portion of the value of his Account in any Investment Fund to another Investment Fund.”

     4. Section 10.2 of the Plan is hereby restated in its entirety to read as follows:

     “10.2 Voluntary Withdrawals.

     10.2.1 Regular Withdrawal Without Suspension. Subject to such rules as the
Plan Administrator may from time to time prescribe, an active Participant may make a
withdrawal from his After-Tax Contributions Account and from his Prior Company Matching
Contributions Account up to two (2) times in any given Plan Year by filing a written notice
with the Plan Administrator. Withdrawals shall be made in the following order and
classification:

          10.2.1.1 First, from the Participant’s After-Tax Contributions,

          10.2.1.2 Second, from the earnings on his After-Tax Contributions Account, and

          10.2.1.3 Finally, from his Prior Company Matching Contributions Account.”

     5. New Sections 10.4.3.6 and 10.4.3.7 are hereby added to the Plan to read as follows:

“10.4.3.6 Expenses for the repair of damage to the Participant’s principal residence that
would qualify for the casualty deduction under section 1023(aa)(2)(F) of the PR Code.

“10.4.3.7 Such other circumstances or events as may be prescribed by the Puerto Rico
Secretary of the Treasury or his delegate.”

     6. Appendix A to the Plan is hereby amended to read as attached hereto as Appendix A.

Executed this 20th day of December, 2007.

	 	 	 	 	 
	 	SB Pharmco Puerto Rico Inc.,

a GlaxoSmithKline company

 	 
	 	By:  	/s/ Donald F. Parman
 	 
	 	 	Name:  	Donald F. Parman 	 
	 	 	Title:  	Assistant Secretary 	 
	 

-2-

 

APPENDIX A

GSK PUERTO RICO RETIREMENT SAVINGS PLAN

Affiliate Companies Participating in the Plan

(As of July 1, 2007)

	•	 	SB Pharmco Puerto Rico Inc.

	•	 	GlaxoSmithKline Consumer Healthcare, L.P.

	•	 	GlaxoSmithKline Puerto Rico Inc.

-3-exv4w8

Exhibit 4.8

AMENDMENT NO. 2

TO THE

GSK PUERTO RICO RETIREMENT SAVINGS PLAN

(Amended and Restated Effective July 1, 2001)

 

          Pursuant to resolutions of the Board of Directors of SmithKline Beecham (Cork) Limited,
adopted December 17th, 2008, the GSK Puerto Rico Retirement Savings Plan (the “Plan”) is
hereby amended as follows effective July 3, 2008, unless otherwise noted:

     1. Each of the definitions in the Plan noted below are hereby restated in their entirety to
read as follows:

	 	 	 	“Board of Directors” means the Board of Directors of SmithKline Beecham (Cork)
Limited.
	 
	 	 	 	“Company” means SmithKline Beecham (Cork) Limited, an Ireland corporation, or
any successor corporation resulting from merger, consolidation, or transfer of assets
substantially as a whole, which shall expressly agree in writing to continue the Plan.

     2. Effective January 1, 2009, the first sentence of Section 5.1.1 of the Plan is hereby
restated in its entirety to read as follows:

     “5.1.1 Each active Participant may designate a percentage of his Compensation (in
1% increments), not to exceed the lesser of 50% of his Compensation or the $9,000 limit
contained in Section 1165(e)(7) of the PR Code ($9,000 for 2009), as Pre-Tax
Contributions in any calendar year; provided that, annual Pre-Tax Contributions by an
active Participant who also contributes to an individual retirement account described in
PR Code Section 1169 will be further limited to the extent required by the PR Code.”

     3. Appendix A to the Plan is hereby amended to read in the form attached hereto.

	 	 	 	Executed this 17th day of December, 2008.

	 	 	 	 	 
	 	SmithKline Beecham (Cork) Limited

a GlaxoSmithKline company

 	 
	 	By:  	/s/ Finbar Whyte
 	 
	 	 	Name:  	Finbar Whyte 	 
	 	 	Title:  	Director 	 

 

 

	 	 	 	 	 

APPENDIX A

GSK PUERTO RICO RETIREMENT SAVINGS PLAN

Affiliate Companies Participating in the Plan

(As of July 3, 2008)

	•	 	GlaxoSmithKline Consumer Healthcare, L.P.

	•	 	GlaxoSmithKline Puerto Rico Inc.

-2-

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