Document:

Collateral Agreement, dated as of June 18, 2009

 Exhibit 4.17 
 EXECUTION VERSION 
  
  
  
 COLLATERAL AGREEMENT 
 dated as of 
 June 18, 2009, 
 among 
 US ONCOLOGY, INC., 
 THE SUBSIDIARIES OF US ONCOLOGY, INC. 
 IDENTIFIED HEREIN 
 and 
 WILMINGTON TRUST FSB, 
 as Collateral Agent 
  
  
  
  
 [CS&M Ref. 8669-177] 

 TABLE OF CONTENTS 
 ARTICLE I 
 Definitions and Other Rules of Construction

  

					
	 SECTION 1.01.
	  	 Indenture and Intercreditor Agreement
	  	1
	 SECTION 1.02.
	  	 Other Defined Terms
	  	1
	
	 ARTICLE II

	
	 [Intentionally Omitted]

	
	 ARTICLE III

	
	 Pledge of Securities

			
	 SECTION 3.01.
	  	 Pledge
	  	5
	 SECTION 3.02.
	  	 Delivery of the Pledged Collateral
	  	6
	 SECTION 3.03.
	  	 Representations, Warranties and Covenants
	  	7
	 SECTION 3.04.
	  	 Certification of Limited Liability Company and Limited Partnership Interests
	  	9
	 SECTION 3.05.
	  	 Registration in Nominee Name; Denominations
	  	9
	 SECTION 3.06.
	  	 Voting Rights; Dividends and Interest
	  	9
	
	 ARTICLE IV

	
	 Security Interests in Personal Property

			
	 SECTION 4.01.
	  	 Security Interest
	  	12
	 SECTION 4.02.
	  	 Representations and Warranties
	  	14
	 SECTION 4.03.
	  	 Covenants
	  	16
	 SECTION 4.04.
	  	 Other Actions
	  	20
	 SECTION 4.05.
	  	 Covenants Regarding Patent, Trademark and Copyright Collateral
	  	22
	 SECTION 4.06.
	  	 Cash Management System
	  	24
	
	 ARTICLE V

	
	 Remedies

			
	 SECTION 5.01.
	  	 Remedies Upon Default
	  	24
	 SECTION 5.02.
	  	 Application of Proceeds
	  	26
	 SECTION 5.03.
	  	 Grant of License to Use Intellectual Property
	  	26
	 SECTION 5.04.
	  	 Securities Act
	  	27

					
	 ARTICLE VI

	
	 [Intentionally Omitted]

	
	 ARTICLE VII

	
	 Miscellaneous

			
	 SECTION 7.01.
	  	 Notices
	  	28
	 SECTION 7.02.
	  	 Waivers; Amendment
	  	28
	 SECTION 7.03.
	  	 Collateral Agent’s Fees and Expenses; Indemnification
	  	28
	 SECTION 7.04.
	  	 Successors and Assigns
	  	29
	 SECTION 7.05.
	  	 Survival of Agreement
	  	29
	 SECTION 7.06.
	  	 Counterparts; Effectiveness; Several Agreement
	  	29
	 SECTION 7.07.
	  	 Severability
	  	30
	 SECTION 7.08.
	  	 Right of Set-Off
	  	30
	 SECTION 7.09.
	  	 Governing Law; Jurisdiction; Consent to Service of Process
	  	30
	 SECTION 7.10.
	  	 WAIVER OF JURY TRIAL
	  	31
	 SECTION 7.11.
	  	 Headings
	  	31
	 SECTION 7.12.
	  	 Security Interest Absolute
	  	31
	 SECTION 7.13.
	  	 Termination or Release
	  	32
	 SECTION 7.14.
	  	 Additional Subsidiaries
	  	32
	 SECTION 7.15.
	  	 Collateral Agent Appointed Attorney-in-Fact
	  	32
	 SECTION 7.16.
	  	 Intercreditor Agreement Governs
	  	33
	 SECTION 7.17.
	  	 Mortgages
	  	33
	 SECTION 7.18.
	  	 Intercreditor Agent
	  	34

					
	 Schedules
	 		  	
			
	 Schedule I
	 	Subsidiary Guarantors	  	
	 Schedule II
	 	Pledged Stock; Debt Securities	  	
	 Schedule III
	 	Intellectual Property	  	
	 Schedule IV
	 	Commercial Tort Claims	  	
	 Schedule V
	 	Concentration Accounts	  	
			
	 Exhibits
	 		  	
			
	 Exhibit I
	 	Form of Supplement	  	
	 Exhibit II
	 	Form of Perfection Certificate	  	
	 Exhibit III
	 	Form of Patent Security Agreement	  	
	 Exhibit IV
	 	Form of Trademark Security Agreement	  	

 COLLATERAL AGREEMENT (this “Agreement”) dated as of
June 18, 2009, among US ONCOLOGY, INC. (the “Issuer”), a Delaware corporation, the Subsidiary Guarantors identified herein and WILMINGTON TRUST FSB, as collateral agent (in such capacity, together with its successors and
assigns, the “Collateral Agent”). 
 Reference is made to (a) the Indenture dated as of June 18, 2009 (as amended,
supplemented or otherwise modified from time to time, the “Indenture”), among the Issuer, the subsidiaries of the Issuer named therein (the “Subsidiary Guarantors”), and Wilmington Trust FSB, as Trustee, and
(b) the Intercreditor Agreement dated as of June 18, 2009 (as amended, supplemented or otherwise modified from time to time, the “Intercreditor Agreement”), among the Issuer, the Subsidiary Guarantors, the Collateral Agent
and the Intercreditor Agent (as defined therein). The Subsidiary Guarantors are affiliates of the Issuer and will derive substantial benefits from the sale of the securities and are willing to execute and deliver this Agreement in order to induce
the potential investors to purchase the securities issued under the Indenture. Accordingly, the parties hereto agree as follows: 
 ARTICLE I 
 Definitions and Other Rules of Construction 
 SECTION 1.01. Indenture and Intercreditor Agreement. (a) Capitalized terms used in this Agreement and not otherwise defined in
this Agreement have the respective meanings assigned thereto in the Indenture or the Intercreditor Agreement. All terms defined in the New York UCC (as defined in this Agreement) and not defined in this Agreement have the meanings specified therein.

 (b) The rules of construction specified in Section 1.04 of the Indenture also apply to this Agreement, mutatis mutandis.

 (c) Section 11.11 of the Indenture shall be deemed to be incorporated by reference herein. 
 SECTION 1.02. Other Defined Terms. As used in this Agreement, the following terms have the meanings specified below: 
 “Account Debtor” means any Person who is or who may become obligated to any Grantor under, with respect to or on account of
an Account. 
 “Article 9 Collateral” has the meaning assigned to such term in Section 4.01.

 “Collateral” means Article 9 Collateral and Pledged Collateral. 

 “Collateral Agent” has the meaning assigned to such term in the preliminary
statement. 
 “Concentration Accounts” mean those accounts listed on Schedule V and any other account
designated by a Grantor which is subject to the terms of a deposit account control agreement in a form reasonably satisfactory to the Collateral Agent. 
 “Copyright License” means any written agreement, now or hereafter in effect, granting any right to any third party under any Copyright now or hereafter owned by any Grantor or that such
Grantor otherwise has the right to license, or granting any right to any Grantor under any Copyright now or hereafter owned by any third party, and all rights of any Grantor under any such agreement. 
 “Copyrights” means all of the following now owned or hereafter acquired by any Grantor: (a) all copyright rights in
any work subject to the copyright laws of the United States or any other country, whether as author, assignee, transferee or otherwise and (b) all registrations and applications for registration of any such copyright in the United States or any
other country, including registrations, recordings, supplemental registrations and pending applications for registration in the United States Copyright Office (or any similar office in any other country), including, in the case of clauses
(a) and (b), those listed on Schedule III. 
 “Discharge of First-Priority Lien Obligations” shall
have the meaning assigned to such term in the Intercreditor Agreement. 
 “Equity Interests” means shares of
capital stock, partnership interests, membership interest in a limited liability company, beneficial interests in a trust or other equity ownership interests in a Person, and any warrants, options or other rights entitling the holder thereof to
purchase or acquire any such equity interest from the issuer thereof. 
 “Existing Credit Agreement” means the
Credit Agreement, dated August 20, 2004 (as amended by Amendment No. 1, dated March 17, 2005, Amendment No. 2, dated November 15, 2005, Amendment No. 3, dated July 10, 2006, Amendment No. 4, dated
December 21, 2006, Amendment No. 5 dated March 1, 2007, Amendment No. 6 dated November 7, 2007 and Amendment No. 7 dated June 3, 2009), among U.S. Oncology Holdings Inc., the Issuer, as the borrower, the lenders
party thereto, JPMorgan Chase Bank N.A., as administrative agent and collateral agent, Wachovia Bank, National Association, as syndication agent and Citicorp North America, Inc., as documentation agent. 
 “Federal Securities Laws” has the meaning assigned to such term in Section 5.04. 
 “Financial Officer” means the chief financial officer, principal accounting officer, treasurer or controller of the Issuer.

 “Foreign Subsidiary” means any Subsidiary which is not organized under the laws of the United States of
America or any State thereof or the District of Columbia. 
  

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 “General Intangibles” means all “General Intangibles” of any
Grantor as defined in Section 9-102(42) of the UCC. 
 “Governmental Authority” means the government of
the United States of America, any other nation or any political subdivision thereof, whether state or local, and any agency, authority, instrumentality, regulatory body, court, central bank or other entity exercising executive, legislative,
judicial, taxing, regulatory or administrative powers or functions of or pertaining to government. 
 “Grantors” means the Issuer and the Subsidiary Guarantors. 
 “Indenture” has the
meaning assigned to such term in the preliminary statement of this Agreement. 
 “Indenture Documents” means
(a) the Indenture, the Securities, this Agreement and the other Security Documents and (b) any related documents or instruments executed and delivered pursuant to the Indenture or any Security Document, in each case, as such agreements may
be amended, restated, supplemented or otherwise modified from time to time. 
 “Instrument” has the meaning
specified in Article 9 of the New York UCC. 
 “Intellectual Property” means all intellectual and similar
property of any Grantor of every kind and nature now owned or hereafter acquired by any Grantor, including inventions, designs, Patents, Copyrights, Licenses, Trademarks, trade secrets, confidential or proprietary technical and business information,
know-how or other data or information, software and databases and all embodiments or fixations thereof and related documentation, registrations and franchises, and all additions, improvements and accessions to, and books and records describing or
used in connection with, any of the foregoing. 
 “License” means any Patent License, Trademark License,
Copyright License or other license or sublicense agreement to which any Grantor is a party, including those listed on Schedule III. 
 “New York UCC” means the Uniform Commercial Code as from time to time in effect in the State of New York. 
 “Obligations” has the meaning assigned to such term in the Indenture. 
 “Patent License” means any written agreement, now or hereafter in effect, granting to any third party any right to make, use or sell any invention on which a Patent, now or hereafter owned by any Grantor or that any Grantor
otherwise has the right to license, is in existence, or granting to any Grantor any right to make, use or sell any invention on which a patent, now or hereafter owned by any third party, is in existence, and all rights of any Grantor under any such
agreement. 
  

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 “Patents” means all of the following now owned or hereafter acquired by any
Grantor: (a) all letters patent of the United States or the equivalent thereof in any other country, all registrations and recordings thereof, and all applications for letters patent of the United States or the equivalent thereof in any other
country, including registrations, recordings and pending applications in the United States Patent and Trademark Office or any similar offices in any other country, including those listed on Schedule III, and (b) all reissues,
continuations, divisions, continuations-in-part, renewals or extensions thereof, and the inventions disclosed or claimed therein, including the right to make, use and/or sell the inventions disclosed or claimed therein. 
 “Patent Agreement” means the Patent Security Agreement substantially in the form attached hereto as Exhibit III.

 “Perfection Certificate” means a certificate substantially in the form of Exhibit II, completed and
supplemented with the schedules and attachments contemplated thereby, and duly executed by a Financial Officer and a legal officer of the Issuer. 
 “Pledged Collateral” has the meaning assigned to such term in Section 3.01. 
 “Pledged Debt Securities” has the meaning assigned to such term in Section 3.01. 
 “Pledged Securities” means any promissory notes, stock certificates or other securities now or hereafter included in the Pledged Collateral, including all certificates, instruments or
other documents representing or evidencing any Pledged Collateral. 
 “Pledged Stock” has the meaning assigned
to such term in Section 3.01. 
 “Proceeds” has the meaning specified in Section 9-102 of the New
York UCC. 
 “Secured Parties” means (a) the Collateral Agent, (b) each Holder, (c) the Trustee,
(d) the beneficiaries of each indemnification obligation undertaken by the Issuer or any Subsidiary Guarantor under any Indenture Document and (e) the successors and assigns of each of the foregoing. 
 “Security Interest” has the meaning assigned to such term in Section 4.01. 
 “Taxes” means any and all present or future taxes, levies, imposts, duties, deductions, charges or withholdings imposed by
any Governmental Authority. 
 “Trademark License” means any written agreement, now or hereafter in effect,
granting to any third party any right to use any Trademark now or hereafter owned by any Grantor or that any Grantor otherwise has the right to license, or granting to any Grantor any right to use any Trademark now or hereafter owned by any third
party, and all rights of any Grantor under any such agreement. 
  

 4 

 “Trademarks” means all of the following now owned or hereafter acquired by
any Grantor: (a) all trademarks, service marks, trade names, corporate names, company names, business names, fictitious business names, trade styles, trade dress, logos, other source or business identifiers, designs and general intangibles of
like nature, now existing or hereafter adopted or acquired, all registrations and recordings thereof, and all registration and recording applications filed in connection therewith, including registrations and registration applications in the United
States Patent and Trademark Office or any similar offices in any State of the United States or any other country or any political subdivision thereof, and all extensions or renewals thereof, including those listed on Schedule III, (b) all
goodwill associated therewith or symbolized thereby and (c) all other assets, rights and interests that uniquely reflect or embody such goodwill. 
 “Trademark Agreement” means the Trademark Security Agreement substantially in the form attached hereto as Exhibit IV. 
 ARTICLE II 
 [Intentionally Omitted] 
 ARTICLE III 
 Pledge
of Securities 
 SECTION 3.01. Pledge. As security for the payment or performance, as applicable, in full of the
Obligations, each Grantor hereby grants to the Collateral Agent, its successors and assigns, for the ratable benefit of the Secured Parties, a security interest in, all of such Grantor’s right, title and interest in, to and under (a) the
shares of capital stock and other Equity Interests of each Subsidiary owned by it and listed on Schedule II and any other Equity Interests of a Subsidiary obtained in the future by such Grantor and the certificates representing all such Equity
Interests (the “Pledged Stock”), provided that the Pledged Stock shall not include more than (i) 65% of the outstanding voting Equity Interests of any Foreign Subsidiary; or (ii) the Pledged Stock of any Person that
is not a direct or indirect wholly-owned subsidiary of the Issuer to the extent the grant of such security interest would (A) constitute a violation of a valid and enforceable restriction in respect of, or result in the abandonment,
invalidation or unenforceability of any right, title or interest of such Grantor in, such Pledged Stock in favor of a third party or under any law, regulation, permit, order, judgment or decree of any Governmental Authority (for the avoidance of
doubt, the restrictions described herein are not negative pledges or similar undertakings in favor of a lender or other financial counterparty) or (B) result in a material breach, termination or default under any contract, lease, instrument,
franchise, permit, license or other document relating to any such Pledged Stock, or give any other party the right to terminate its obligations or such Grantor’s rights under such contract, lease, instrument, franchise, permit, license or other
document (whether expressly in such document or otherwise under applicable law); provided further (x) that the capital stock

  

 5 

 
and other Equity Interests of any Subsidiary that are owned by any Grantor will constitute Pledged Stock only to the extent that such capital stock and other Equity Interests can secure the
Securities without Rule 3-10 or Rule 3-16 of Regulation S-X (or any other law rule or regulation) requiring separate financial statements of such Subsidiary to be filed with the SEC, (y) in the event that either Rule 3-10 or Rule 3-16 of
Regulation S-X requires or is amended modified or interpreted by the SEC to require (or is replaced with another rule or regulation or any other law rule or regulation is adopted, which would require) the filing with the SEC (or any other
governmental agency) of separate financial statements of any Subsidiary due to the fact that such Subsidiary’s capital stock or other Equity Interests constitute Pledged Stock, then such capital stock or other Equity Interests shall
automatically be deemed not to be Pledged Stock but only to the extent necessary to not be subject to such requirement and (z) in the event that either Rule 3-10 or Rule 3-16 of Regulation S-X is amended modified or interpreted by the SEC to
permit (or is replaced with another rule or regulation or any other law rule or regulation is adopted, which would permit) such capital stock or other Equity Interests to constitute Pledged Stock without the filing with the SEC (or any other
governmental agency) of separate financial statements of such Subsidiary, then such capital stock and other Equity Interests shall automatically be deemed to be Pledged Stock but only to the extent necessary to not be subject to any such financial
statement requirement; (b)(i) the debt securities listed opposite the name of such Grantor on Schedule II, (ii) any debt securities issued after the Issue Date to such Grantor by the Issuer and each Subsidiary and (iii) the
promissory notes and any other instruments evidencing such debt securities (the “Pledged Debt Securities”); (c) all other property that may be delivered to and held by the Collateral Agent pursuant to the terms of this
Section 3.01; (d) subject to Section 3.06, all payments of principal or interest, dividends, cash, instruments and other property from time to time received, receivable or otherwise distributed in respect of, in exchange for or upon
the conversion of, and all other Proceeds received in respect of, the securities referred to in clauses (a), (b) and (c) above; (e) subject to Section 3.06, all rights and privileges of such Grantor with respect to the
securities and other property referred to in clauses (a), (b), (c) and (d) above; and (f) all Proceeds of any of the foregoing (the items referred to in clauses (a) through (f) above being collectively referred to as
the “Pledged Collateral”). 
 TO HAVE AND TO HOLD the Pledged Collateral, together with all right, title,
interest, powers, privileges and preferences pertaining or incidental thereto, unto the Collateral Agent, its successors and assigns, for the ratable benefit of the Secured Parties, forever, subject, however, to the terms, covenants
and conditions hereinafter set forth. 
 SECTION 3.02. Delivery of the Pledged Collateral. (a) Each Grantor agrees
promptly to deliver or cause to be delivered to the Collateral Agent (or, prior to the Discharge of First-Priority Lien Obligations, to the Intercreditor Agent, acting as a gratuitous bailee of the Collateral Agent) any and all (i) Pledged
Stock, (ii) to the extent required to be delivered pursuant to paragraph (b) of this Section 3.02, Pledged Debt Securities and (iii) to the extent required to be delivered pursuant to paragraph (c) of this Section 3.02,
any other Pledged Securities to the extent certificated. 
 (b) Each Grantor will cause any Indebtedness for borrowed money owed
to such Grantor (i) by any Grantor to be evidenced by a duly executed promissory note

  

 6 

 
that is pledged and delivered to the Collateral Agent (or, prior to the Discharge of First-Priority Lien Obligations, to the Intercreditor Agent, acting as a gratuitous bailee of the Collateral
Agent) pursuant to the terms hereof and (ii) by any other Person which is (A) in excess of $500,000 and (B) evidenced by a duly executed promissory note to be pledged and delivered to the Collateral Agent (or, prior to the Discharge
of First-Priority Lien Obligations, to the Intercreditor Agent, acting as a gratuitous bailee of the Collateral Agent) pursuant to the terms hereof. 
 (c) Upon delivery to the Collateral Agent (or, prior to the Discharge of First-Priority Lien Obligations, to the Intercreditor Agent, acting as a gratuitous bailee of the Collateral Agent), (i) any
Pledged Securities shall be accompanied by undated stock powers duly executed in blank or other undated instruments of transfer reasonably satisfactory to the Intercreditor Agent and by such other instruments and documents as the Intercreditor Agent
may reasonably request pursuant to any Senior Collateral Document and (ii) all other property comprising part of the Pledged Collateral shall be accompanied by proper instruments of assignment duly executed by the applicable Grantor and such
other instruments or documents as the Intercreditor Agent may reasonably request. Each delivery of Pledged Securities shall be accompanied by a schedule describing such Pledged Securities, which schedule shall be attached hereto as a supplement to
Schedule II and made a part hereof, provided that failure to attach any such schedule hereto shall not affect the validity of such pledge of such Pledged Securities. Each schedule so delivered shall supplement any prior schedules so
delivered. 
 (d) Notwithstanding anything herein to the contrary, prior to the Discharge of the First-Priority Lien
Obligations, to the extent any Grantor is required hereunder to deliver Collateral to the Collateral Agent for purposes of possession and control and is unable to do so as a result of having previously delivered such Collateral to the Intercreditor
Agent in accordance with the terms of the First-Priority Lien Security Agreement, such Grantor’s obligations hereunder with respect to such delivery shall be deemed satisfied by the delivery to the Intercreditor Agent, acting as gratuitous
bailee of the Collateral Agent. 
 SECTION 3.03. Representations, Warranties and Covenants. The Grantors jointly and
severally represent, warrant and covenant to and with the Collateral Agent, for the benefit of the Secured Parties, that: 
 (a) Schedule II correctly sets forth, as of the Issue Date and as of each date on which a supplement to Schedule II is delivered pursuant to Section 3.02(c), the percentage of the issued and
outstanding shares (or units or other comparable measure) of each class of the Equity Interests of the issuer thereof represented by the Pledged Stock and includes all Equity Interests, debt securities and promissory notes required to be pledged
hereunder; 
 (b) the Pledged Stock and Pledged Debt Securities have been duly and validly authorized and issued
by the issuers thereof and (i) in the case of Pledged Stock, are fully paid and nonassessable and (ii) in the case of Pledged Debt Securities (solely with respect to Pledged Debt Securities issued by a Person other than the Issuer or a
Subsidiary of the Issuer, to the best of the Issuer’s knowledge), are legal, valid and binding obligations of the issuers thereof; 
  

 7 

 (c) except for the security interests granted hereunder, each of the
Grantors (i) is and, subject to any transfers made in compliance with the Indenture, will continue to be the direct owner, beneficially and of record, of the Pledged Securities indicated on Schedule II as owned by such Grantor, (ii) holds
the same free and clear of all Liens, other than Liens created by any Indenture Document and Permitted Liens, (iii) will make no assignment, pledge, hypothecation or transfer of, or create or permit to exist any security interest in or other
Lien on, the Pledged Collateral, other than Liens created by any Indenture Document, Permitted Liens and transfers made in compliance with the Indenture, and (iv) will defend its title or interest thereto or therein against any and all Liens
(other than Liens created by any Indenture Document and Permitted Liens), however arising, of all Persons whomsoever; 
 (d) except for restrictions and limitations imposed by (i) the Indenture Documents, (ii) securities laws generally, (iii) in the case of Pledged Stock Persons that are not Subsidiary Guarantors, transfer restrictions that
exist at the time of acquisition of such Equity Interests (provided that the Grantors used commercially reasonable efforts to limit such transfer restrictions) or (iv) customary provisions in joint venture agreements relating to purchase
options, rights for first refusal or call or similar rights of a third party that owns Equity Interests in such joint venture, the Pledged Collateral is and will continue to be freely transferable and assignable, and except as described in the
Perfection Certificate, none of the Pledged Collateral is or will be subject to any option, right of first refusal, shareholders agreement, charter or by-law provision or contractual restriction of any nature that might prohibit, impair, delay or
otherwise affect in a manner adverse to the Secured Parties, the pledge of such Pledged Collateral hereunder, the sale or disposition thereof pursuant hereto or the exercise by the Collateral Agent of rights and remedies hereunder; 
 (e) each of the Grantors has the power and authority to pledge the Pledged Collateral pledged by it hereunder in the manner
hereby done or contemplated; 
 (f) no consent or approval of any Governmental Authority, any securities exchange
or any other Person was or is necessary to the validity of the pledge effected hereby (other than such as have been obtained and are in full force and effect); 
 (g) by virtue of the execution and delivery by the Grantors of this Agreement, when any Pledged Securities are delivered to
the Collateral Agent (or, prior to the Discharge of First-Priority Lien Obligations, to the Intercreditor Agent, acting as a gratuitous bailee of the Collateral Agent) in accordance with this Agreement, the Collateral Agent will obtain, for the
benefit of the Secured Parties, a legal, valid and perfected lien upon and security interest in such Pledged Securities as security for the payment and performance of the Obligations; and 
  

 8 

 (h) the pledge effected hereby is effective to vest in the Collateral Agent,
for the ratable benefit of the Secured Parties, the rights of the Collateral Agent in the Pledged Collateral as set forth in this Agreement. 
 SECTION 3.04. Certification of Limited Liability Company and Limited Partnership Interests. (a) Each Grantor acknowledges and agrees that (i) each interest in any limited liability
company or limited partnership wholly-owned by any Grantor and acquired after the Issue Date and pledged hereunder shall be represented by a certificate, shall be a “security” within the meaning of Article 8 of the New York UCC and shall
be governed by Article 8 of the New York UCC and (ii) each such interest shall at all times thereafter be represented only by a certificate. 
 (b) Each Grantor further acknowledges and agrees that (i) the interests in any limited liability company or limited partnership controlled by such Grantor and pledged hereunder that are not
represented by a certificate are not “securities” within the meaning of Article 8 of the New York UCC and (ii) such Grantor shall at no time elect to treat any such interest as a “security” within the meaning of Article 8 of
the New York UCC or issue any certificate representing such interest, unless such Grantor provides prior written notification to the Collateral Agent of such election and immediately pledges any such certificate to the Collateral Agent pursuant to
the terms hereof. 
 SECTION 3.05. Registration in Nominee Name; Denominations. Following the Discharge of First-Priority
Lien Obligations, the Collateral Agent, on behalf of the Secured Parties, shall have the right (in its sole and absolute discretion) to hold the Pledged Securities in the name of the applicable Grantor, endorsed or assigned in blank or in favor of
the Collateral Agent or, upon the occurrence and during the continuance of an Event of Default and with written notice to the applicable Grantor given concurrently (if possible after using reasonable efforts) or promptly thereafter (and in any event
within five days), in its own name as pledgee or the name of its nominee (as pledgee or as sub-agent); provided that any failure by the Collateral Agent to provide notice shall not affect the Collateral Agent’s Security Interest in the
Pledged Securities or rights hereunder. Each Grantor will promptly give to the Collateral Agent copies of any notices or other communications received by it with respect to Pledged Securities registered in the name of such Grantor. The Collateral
Agent shall at all times upon the occurrence and during the continuance of an Event of Default have the right to exchange the certificates representing Pledged Securities for certificates of smaller or larger denominations for any purpose consistent
with this Agreement in the case of Pledged Securities of Persons that are not Subsidiaries, to the extent permitted by the documentation governing such Pledged Securities. Each Grantor shall use its commercially reasonable efforts to cause any
Subsidiary of the Company that is not party to this Agreement to comply with request by the Collateral Agent pursuant to this Section 3.05 to exchange certificates representing Pledged Securities of such Subsidiary of the Company for
certificates of smaller or larger denominations. 
 SECTION 3.06. Voting Rights; Dividends and Interest. (a) Unless
and until an Event of Default shall have occurred and be continuing and the Collateral Agent shall have notified the Grantors that their rights under this Section 3.06 are being suspended: 
  

 9 

 (i) Each Grantor shall be entitled to exercise any and all voting and other
consensual rights and powers inuring to an owner of Pledged Securities or any part thereof for any purpose consistent with the terms of this Agreement, the Indenture and the other Indenture Documents, provided that such rights and powers
shall not be exercised in any manner that would reasonably be expected to materially and adversely affect the rights inuring to a holder of any Pledged Securities or the rights and remedies of any of the Collateral Agent or the other Secured Parties
under this Agreement or the Indenture or any other Indenture Document or the ability of the Secured Parties to exercise the same. 
 (ii) The Collateral Agent shall execute and deliver to each Grantor, or cause to be executed and delivered to such Grantor, all such proxies, powers of attorney and other instruments as such Grantor may
reasonably request for the purpose of enabling such Grantor to exercise the voting and other consensual rights and powers it is entitled to exercise pursuant to subparagraph (i) above. 
 (iii) Each Grantor shall be entitled to receive and retain any and all dividends, interest, principal and other distributions
paid on or distributed in respect of the Pledged Securities to the extent and only to the extent that such dividends, interest, principal and other distributions are permitted by, and otherwise paid or distributed in accordance with, the terms and
conditions of the Indenture, the other Indenture Documents and applicable laws, provided that any noncash dividends, interest, principal or other distributions that would constitute Pledged Stock or Pledged Debt Securities, whether resulting
from a subdivision, combination or reclassification of the outstanding Equity Interests of the issuer of any Pledged Securities or received in exchange for Pledged Securities or any part thereof, or in redemption thereof, or as a result of any
merger, consolidation, acquisition or other exchange of assets to which such issuer may be a party or otherwise, shall be and become part of the Pledged Collateral, and, if received by any Grantor, shall not be commingled by such Grantor with any of
its other funds or property but shall be held separate and apart therefrom, shall be held in trust for the benefit of the Collateral Agent and the other Secured Parties and shall be forthwith delivered to the Collateral Agent in the same form as so
received (with any necessary endorsement as described in Section 3.03(c) or otherwise). So long as no Default or Event of Default has occurred and is continuing, the Collateral Agent shall promptly deliver (after reasonable advance notice) to
the applicable Grantor Pledged Securities pledged by such Grantor in its possession if requested to be delivered to the Issuer thereof in connection with any exchange or redemption of such Pledged Securities permitted under the Indenture.

 (b) Upon the occurrence and during the continuance of an Event of Default, after the Collateral Agent shall have notified the
Grantors of the suspension of their rights under paragraph (a)(iii) of this Section 3.06, all rights of any Grantor to dividends, interest, principal or other distributions that such Grantor is authorized to

  

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receive pursuant to paragraph (a)(iii) of this Section 3.06 shall cease, and all such rights shall thereupon become vested in the Collateral Agent, which shall have the sole and
exclusive right and authority to receive and retain such dividends, interest, principal or other distributions. All dividends, interest, principal or other distributions received by any Grantor contrary to the provisions of this Section 3.06
shall be held in trust for the benefit of the Collateral Agent and the other Secured Parties, shall be segregated from other property or funds of such Grantor and shall be forthwith delivered to the Collateral Agent upon demand in the same form as
so received (with any necessary endorsement). Any and all money and other property paid over to or received by the Collateral Agent pursuant to the provisions of this paragraph (b) shall be retained by the Collateral Agent in an account to be
established by the Collateral Agent upon receipt of such money or other property and shall be applied in accordance with the provisions of Section 5.02. After all Events of Default have been cured or waived and the Issuer has delivered to the
Collateral Agent a certificate to that effect, the Collateral Agent shall promptly repay to each Grantor (without interest) all dividends, interest, principal or other distributions that such Grantor would otherwise be permitted to retain pursuant
to the terms of paragraph (a)(iii) of this Section 3.06 and that remain in such account. 
 (c) Upon the occurrence and
during the continuance of an Event of Default, after the Collateral Agent shall have notified the Grantors of the suspension of their rights under paragraph (a)(i) of this Section 3.06, all rights of any Grantor to exercise the voting and other
consensual rights and powers it is entitled to exercise pursuant to paragraph (a)(i) of this Section 3.06, and the obligations of the Collateral Agent under paragraph (a)(ii) of this Section 3.06, shall cease, and all such rights
shall thereupon become vested in the Collateral Agent, which shall have the sole and exclusive right and authority to exercise such voting and other consensual rights and powers, provided that, unless otherwise directed by the Holders of at
least a majority in aggregate principal amount of the Securities then outstanding, the Collateral Agent shall have the right from time to time following and during the continuance of an Event of Default to permit the Grantors to exercise such
rights. After all Events of Default have been cured or waived and the Issuer has delivered to the Collateral Agent a certificate to that effect, the Grantors shall have the exclusive right to exercise the voting and consensual rights and powers that
they would otherwise be entitled to exercise pursuant to the terms of paragraph (a)(i) above. 
 (d) Any notice given by the
Collateral Agent to the Grantors suspending their rights under paragraph (a) of this Section 3.06 (i) may be given by telephone if promptly confirmed in writing, (ii) may be given to one or more of the Grantors at the same or
different times and (iii) may suspend the rights of the Grantors under paragraph (a)(i) or paragraph (a)(iii) of this Section 3.06 in part without suspending all such rights (as specified by the Collateral Agent in its sole and absolute
discretion) and without waiving or otherwise affecting the Collateral Agent’s rights to give additional notices from time to time suspending other rights so long as an Event of Default has occurred and is continuing. 
  

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 ARTICLE IV 
 Security Interests in Personal Property 
 SECTION 4.01. Security Interest.
(a) As security for the payment or performance, as applicable, in full of the Obligations, each Grantor hereby grants to the Collateral Agent, its successors and assigns, for the ratable benefit of the Secured Parties, a security interest (the
“Security Interest”) in all right, title or interest in or to any and all of the following assets and properties now owned or at any time hereafter acquired by such Grantor or in which such Grantor now has or at any time in the
future may acquire any right, title or interest (collectively, the “Article 9 Collateral”): 
 (i) all Accounts; 
 (ii) all Chattel Paper; 
 (iii) all cash and Deposit Accounts; 
 (iv) all Documents; 
 (v) all Equipment; 
 (vi) all General Intangibles; 
 (vii) all Instruments; 
 (viii) all Inventory; 
 (ix) all Investment Property; 

(x) until the termination of the Existing Credit Agreement, all Letter-of-credit rights; 
 (xi) until the termination of the Existing Credit Agreement, the commercial tort claims specified on Schedule IV; 

(xii) all books and records pertaining to the Article 9 Collateral; and 
 (xiii) to the extent not otherwise included, all Proceeds and products of any and all of the foregoing and all collateral
security, supporting obligations and guarantees given by any Person with respect to any of the foregoing; 
 provided that
notwithstanding anything to the contrary in this Agreement, this Agreement shall not constitute a grant of a security interest in (A) motor vehicles the perfection of a security interest in which is excluded from the UCC in the relevant
jurisdiction, (B) any Equipment that is subject to a purchase money lien or a capital lease permitted under the Indenture to the extent the documents relating to such purchase money lien or capital lease prohibits such Equipment to be subject
to the Security Interest created hereby, (C)

  

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any intent-to-use Trademark applications to the extent that, and solely during the period in which, the grant of a security interest therein would impair the validity or enforceability of such
intent-to-use Trademark applications under applicable federal law, or (D) any General Intangibles, Investment Property, Accounts, Intellectual Property, promissory notes, chattel paper, or other such rights of a Grantor if (but only to the
extent that) the grant of a security interest therein would (x) constitute a violation of a valid and enforceable restriction in respect of, or result in the abandonment, invalidation or unenforceability of any right, title or interest of such
Grantor in, such General Intangibles, Investment Property, Accounts, Intellectual Property, promissory notes, chattel paper, or other such rights in favor of a third party or under any law, regulation, permit, order, judgment or decree of any
Governmental Authority, unless and until all required consents shall have been obtained (for the avoidance of doubt, the restrictions described herein are not negative pledges or similar undertakings in favor of a lender or other financial
counterparty) or (y) result in a breach, termination or default under any contract, lease, instrument, franchise, permit, license or other document relating to any such General Intangibles, Investment Property, Accounts, Intellectual Property,
promissory notes, chattel paper, or other such rights of a Grantor, or give any other party the right to terminate its obligations or such Grantor’s rights under such contract, lease, instrument, franchise, permit, license or other document
(whether expressly in such document or otherwise under applicable law), provided however, that the limitation set forth in clause (C) above shall not affect, limit, restrict or impair the grant by a Grantor of a security interest pursuant to
this Agreement in any such Collateral to the extent that an otherwise applicable prohibition or restriction on such grant is rendered ineffective by any applicable law, including the New York UCC; provided further, that the limitations set
forth in clause (B) above shall not restrict the grant by a Grantor of a subordinated security interest with respect to such Property to the extent permitted under the applicable agreements governing such Property. Notwithstanding the
limitations set forth in clause (D) above, each Grantor agrees to use commercially reasonable efforts to obtain any consents required in connection with the grant of a security interest in any General Intangible, Investment Property, Accounts,
Intellectual Property, promissory notes, chattel paper or other such rights of the Grantor acquired after the Issue Date that generates revenue in excess of $500,000 annually or has a Fair Market Value in excess of $1,000,000; provided,
however, that no Grantor shall be obligated to use commercially reasonable efforts to obtain such consents in connection with the grant of security interests in any General Intangibles or other rights arising under any joint venture
agreements. 
 (b) Each Grantor hereby irrevocably authorizes the Collateral Agent at any time and from time to time to file in
any relevant jurisdiction any initial financing statements (including fixture filings) with respect to the Article 9 Collateral or any part thereof and amendments thereto that (i) indicate the Collateral as “all assets” of such
Grantor or such other description as the Collateral Agent may determine and (ii) contain the information required by Article 9 of the Uniform Commercial Code of each applicable jurisdiction for the filing of any financing statement or
amendment, including (A) whether such Grantor is an organization, the type of organization and any organizational identification number issued to such Grantor and (B) in the case of a financing statement filed as a fixture filing, a
sufficient description of the real property to which such Article 9 Collateral relates. Each Grantor agrees to provide such information to the Collateral Agent promptly upon request. 
  

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 Each Grantor also ratifies its authorization for the Collateral Agent to file in any
relevant jurisdiction any initial financing statements (including fixture filings, as applicable) or other appropriate filings, recordings or registrations or amendments thereto if filed prior to the date hereof. 
 The Collateral Agent is further authorized to file with the United States Patent and Trademark Office or United States Copyright Office (or
any successor office or any similar office in any other country) such documents as may be necessary or advisable for the purpose of perfecting, confirming, continuing, enforcing or protecting the Security Interest granted by each Grantor, without
the signature of any Grantor, and naming any Grantor or the Grantors as debtors and the Collateral Agent as secured party. 
 (c) The Security Interest is granted as security only and shall not subject the Collateral Agent or any other Secured Party to, or in any way alter or modify, any obligation or liability of any Grantor with respect to or arising out of the
Article 9 Collateral. 
 (d) Each of the parties hereto acknowledges and agrees that any provision of this Agreement to the
contrary notwithstanding, until the Discharge of First-Priority Lien Obligations, the Grantors shall not be required to act or refrain from acting under this Agreement with respect to the Collateral in any manner that would be contrary to or would
otherwise result in a Default or Event of Default under the terms and provisions of the Senior Collateral Documents and no such failure to act or refrain from acting shall constitute a Default or Event of Default under the Indenture Documents.

 (e) Notwithstanding anything to the contrary herein, no Grantor shall be required to perfect the Security Interests granted
by this Agreement in any Deposit Account or securities or other investment account except in accordance with Section 4.06(a). The Collateral Agent agrees that it will not give any instructions under any deposit account or other control
agreement or withhold any withdrawal rights with respect to funds or securities in any Deposit Account or securities or other investment account subject thereto unless and until an Event of Default has occurred and is continuing. 
 SECTION 4.02. Representations and Warranties. The Grantors jointly and severally represent and warrant to the Collateral Agent and
the other Secured Parties that: 
 (a) Each Grantor has good and valid rights in and title to the Article 9 Collateral and
has full power and authority to grant to the Collateral Agent, for the ratable benefit of the Secured Parties, the Security Interest in such Article 9 Collateral pursuant hereto and to execute, deliver and perform its obligations in accordance
with the terms of this Agreement, without the consent or approval of any other Person other than any consent or approval that has been obtained. 
  

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 (b) The Perfection Certificate has been duly prepared, completed and executed and the
information set forth therein, including (i) the exact legal name of each Grantor and (ii) the jurisdiction of organization of each Grantor, is correct and complete as of the Issue Date. The Uniform Commercial Code financing statements
(including fixture filings, as applicable) or other appropriate filings, recordings or registrations prepared by the Collateral Agent based upon the information provided to the Collateral Agent in the Perfection Certificate for filing in each
governmental, municipal or other office specified in Schedule 2 to the Perfection Certificate (or specified by notice from the Issuer to the Collateral Agent after the Issue Date in the case of filings, recordings or registrations required by
the Indenture), are all the filings, recordings and registrations (other than filings required to be made in the United States Patent and Trademark Office and the United States Copyright Office in order to perfect the Security Interest in
Article 9 Collateral consisting of United States Patents, United States registered Trademarks (and Trademarks for which United States registration applications are pending) and United States registered Copyrights) that are necessary to publish
notice of and protect the validity of and to establish a legal, valid and perfected security interest in favor of the Collateral Agent, for the ratable benefit of the Secured Parties, in respect of all Article 9 Collateral in which the Security
Interest may be perfected by filing, recording or registration in the United States (or any political subdivision thereof) and its territories and possessions, and no further or subsequent filing, refiling, recording, rerecording, registration or
reregistration is necessary in any such jurisdiction, except as provided under applicable law with respect to the filing of continuation statements. Each Grantor represents and warrants that fully executed agreements in the form of Exhibit III and
Exhibit IV hereto and containing a description of all Article 9 Collateral consisting of Intellectual Property with respect to United States Patents and United States registered Trademarks (and Trademarks for which United States registration
applications are pending) and United States registered Copyrights have been delivered to the Collateral Agent for recording by the United States Patent and Trademark Office and the United States Copyright Office pursuant to
35 U.S.C. § 261, 15 U.S.C. § 1060 or 17 U.S.C. § 205 and the regulations thereunder, as applicable, and otherwise as may be required pursuant to the laws of any other necessary
jurisdiction, to protect the validity of and to establish a legal, valid and perfected security interest in favor of the Collateral Agent, for the ratable benefit of the Secured Parties, in respect of all Article 9 Collateral consisting of
United States Patents, United States registered Trademarks (and Trademarks for which United States registration applications are pending) and United States registered Copyrights in which a security interest may be perfected by filing, recording or
registration in the United States (or any political subdivision thereof) and its territories and possessions, and no further or subsequent filing, refiling, recording, rerecording, registration or reregistration is necessary (other than such actions
as are necessary to perfect the Security Interest with respect to any Article 9 Collateral consisting of United States Patents, United States registered Trademarks (and Trademarks for which United States registration applications are pending)
and United States registered Copyrights acquired or developed after the date hereof). 
 (c) The Security Interest constitutes
(i) a legal and valid security interest in all the Article 9 Collateral securing the payment and performance of the Obligations, (ii) subject to the filings described in Section 4.02(b), a perfected security interest in all

  

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Article 9 Collateral in which a security interest may be perfected by filing, recording or registering a financing statement or analogous document in the United States (or any political
subdivision thereof) and its territories and possessions pursuant to the Uniform Commercial Code and (iii) a security interest that shall be perfected in all Article 9 Collateral in which a security interest may be perfected upon the
receipt and recording of this Agreement (or the Trademark Agreement) with the United States Patent and Trademark Office within the four -month period (commencing as of the date hereof) pursuant to 35 U.S.C. § 261 or 15 U.S.C.
§ 1060 or the four-month period (commencing as of the date hereof) pursuant to 17 U.S.C. § 205 and otherwise as may be required pursuant to the laws of any other necessary jurisdiction. The Security Interest is (to the
extent such Security Interest can be perfected by filing) and shall be prior to any other Lien on any of the Article 9 Collateral, other than Permitted Liens and Liens that have priority as a matter of applicable law. 
 (d) The Article 9 Collateral is owned by the Grantors free and clear of any Lien, except for Permitted Liens. None of the Grantors has
filed or consented to the filing of (i) any financing statement or analogous document under the Uniform Commercial Code or any other applicable laws covering any Article 9 Collateral, (ii) any assignment in which any Grantor assigns
any Collateral or any security agreement or similar instrument covering any Article 9 Collateral with the United States Patent and Trademark Office or the United States Copyright Office or (iii) any assignment in which any Grantor assigns
any Article 9 Collateral or any security agreement or similar instrument covering any Article 9 Collateral with any foreign governmental, municipal or other office, which financing statement or analogous document, assignment, security
agreement or similar instrument is still in effect, except, in each case, for Permitted Liens and assignments permitted by the Indenture. 
 SECTION 4.03. Covenants. (a) Each Grantor agrees promptly to notify the Collateral Agent in writing of any change (i) in its corporate name, (ii) in the location of its chief
executive office or its principal place of business, (iii) in its identity or type of organization or corporate structure, (iv) in its organizational identification number or (v) in its jurisdiction of organization. Each Grantor
agrees to promptly provide the Collateral Agent with certified organizational documents reflecting any of the changes described in the first sentence of this Section 4.03(a). Each Grantor agrees not to effect or permit any change referred to in
the second preceding sentence unless all filings have been made under the Uniform Commercial Code or otherwise that are required in order for the Collateral Agent to continue at all times following such change to have a valid, legal and perfected
first priority security interest (subject to the Intercreditor Agreement and Permitted Liens) in the Article 9 Collateral. 
 (b) Each Grantor agrees to maintain, at its own cost and expense, such complete and accurate records with respect to the Article 9 Collateral owned by it as is consistent with its current practices and in accordance with such standard
practices used in industries that are the same as or similar to those in which such Grantor is engaged, but in any event to include complete accounting records indicating all payments and proceeds received with respect to any part of the
Article 9 Collateral, and, at such time or times as the Intercreditor Agent may reasonably request pursuant to any Senior Collateral

  

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Document, promptly to prepare and deliver to the Collateral Agent a duly certified schedule or schedules in form and detail reasonably satisfactory to the Intercreditor Agent showing the
identity, amount and location of any and all Article 9 Collateral. 
 (c) Each year, at the time of delivery of annual
financial statements with respect to the preceding fiscal year pursuant to Section 4.02 of the Indenture, the Issuer shall deliver to the Collateral Agent a certificate executed by a Financial Officer and the chief legal officer of the Issuer
(i) setting forth the information required pursuant to Schedules 1A, 1B, 1C and 2A (with respect to owned real property only), and Schedules 6, 9, 10 and 12 to the Perfection Certificate or confirming that there has been no change in such
information since the date of the Perfection Certificate delivered on the Issue Date or the date of the most recent certificate delivered pursuant to this Section 4.03(c) and (ii) certifying that all Uniform Commercial Code financing
statements (including fixture filings, as applicable) or other appropriate filings recordings or registrations, including all refilings, rerecordings and registrations, containing a description of the Collateral have been filed of record in each
governmental, municipal or other appropriate office in each jurisdiction identified pursuant to clause (a) of this Section 4.03 to the extent necessary to protect and perfect the Security Interest for a period of not less than
18 months after the date of such certificate (except as noted therein with respect to any continuation statements to be filed within such period). 
 (d) Each Grantor shall, at its own expense, take any and all actions necessary to defend title to the Article 9 Collateral (other than Article 9 Collateral that is deemed immaterial in the
reasonable business judgment of such Grantor) against all Persons and to defend the Security Interest of the Collateral Agent in the Article 9 Collateral and the priority thereof against any Lien that is not a Permitted Lien. Nothing in this
Agreement shall prevent any Grantor from discontinuing the operation or maintenance of any of its assets or properties if such discontinuance is (x) in the reasonable business judgment of such Grantor, desirable in the conduct of its business
and (y) permitted by the Indenture. 
 (e) Each Grantor agrees, at its own expense, to execute, acknowledge, deliver and
cause to be duly filed all such further instruments and documents and take all such actions as the Collateral Agent may from time to time reasonably request to better assure, preserve, protect and perfect the Security Interest and the rights and
remedies created hereby, including the payment of any fees and taxes required in connection with the execution and delivery of this Agreement, the granting of the Security Interest and the filing of any financing statements (including fixture
filings) or other documents (including execution of agreements in the form of Exhibits I and II and filing such agreements with the United States Patent and Trademark Office or United States Copyright Office, as applicable) in connection herewith or
therewith. If any amount payable to any Grantor under or in connection with any of the Article 9 Collateral shall be or become evidenced by any promissory note or other instrument in excess of $500,000, such note or instrument shall be promptly
pledged and delivered to the Collateral Agent (or, prior to the Discharge of First-Priority Lien Obligations, to the Intercreditor Agent, acting as a gratuitous bailee of the Collateral Agent), duly endorsed in a manner reasonably satisfactory to
the Collateral Agent. 
  

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 (f) Following the Discharge of First-Priority Lien Obligations, the Collateral Agent and
such Persons as the Collateral Agent may reasonably designate shall have the right, once in any twelve-month period other than following and during the continuance of an Event of Default, at the Grantors’ own cost and expense, to inspect the
Article 9 Collateral, all records related thereto (and to make extracts and copies from such records) and the premises upon which any of the Article 9 Collateral is located, to discuss the Grantors’ affairs with the officers of the
Grantors and their independent accountants and to verify under reasonable procedures the validity, amount, quality, quantity, value, condition and status of, or any other matter relating to, the Article 9 Collateral, including, (upon the occurrence
and during the continuance of a Default or with the consent of the applicable Grantor (not to be unreasonably withheld)) in the case of Accounts or other Article 9 Collateral in the possession of any third person, by contacting Account Debtors
or the third person possessing such Article 9 Collateral for the purpose of making such a verification. The Collateral Agent shall have the absolute right to share any information it gains from such inspection or verification with any Secured
Party. 
 (g) At its option, the Collateral Agent may discharge, but is not obligated to discharge, past due Taxes, assessments,
charges, fees or Liens at any time levied or placed on the Article 9 Collateral and that is not a Permitted Lien, and may pay for the maintenance and preservation of the Article 9 Collateral to the extent any Grantor fails to do so as
required by the Indenture or this Agreement and within a reasonable period of time after the Collateral Agent has requested it to do so, and each Grantor jointly and severally agrees to reimburse the Collateral Agent within five days after demand
for any payment made or any expense incurred by the Collateral Agent pursuant to the foregoing authorization, provided that nothing in this paragraph shall be interpreted as excusing any Grantor from the performance of, or imposing any
obligation on the Collateral Agent or any Secured Party to cure or perform, any covenants or other promises of any Grantor with respect to Taxes, assessments, charges, fees, Liens and maintenance as set forth in the Indenture, this Agreement or in
the other Indenture Documents. 
 (h) If at any time any Grantor shall take a security interest in any property of an Account
Debtor or any other Person with a value in excess of $500,000 to secure payment and performance of an Account, such Grantor shall promptly assign such security interest to the Collateral Agent. Such assignment need not be filed of public record
unless necessary to continue the perfected status of the security interest against creditors of and transferees from the Account Debtor or other Person granting the security interest. 
 (i) Each Grantor shall remain liable to observe and perform all the conditions and material obligations to be observed and performed by it
under each contract, agreement or instrument relating to the Article 9 Collateral, all in accordance with the terms and conditions thereof, and each Grantor jointly and severally agrees to indemnify and hold harmless the Collateral Agent and
the other Secured Parties from and against any and all liability for such performance. 
  

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 (j) None of the Grantors shall make or permit to be made an assignment, pledge or
hypothecation of the Article 9 Collateral or shall grant any other Lien in respect of the Article 9 Collateral, except as expressly permitted by the Indenture. Subject to the immediately following sentence, none of the Grantors shall make or permit
to be made any transfer of the Article 9 Collateral and each Grantor shall remain at all times in possession of the Article 9 Collateral owned by it, except as permitted by the Indenture or the Intercreditor Agreement. Without limiting the
generality of the foregoing, each Grantor agrees that it shall not permit any Inventory to be in the possession or control of any warehouseman, agent, bailee, or processor at any time unless (x) the aggregate fair value of the Inventory in the
possession of or subject to the control of such Person is less than $500,000 or (y) such Person shall have been notified of the Security Interest and shall have acknowledged in writing, in form and substance reasonably satisfactory to the
Collateral Agent, that such warehouseman, agent, bailee or processor holds the Inventory for the benefit of the Collateral Agent subject to the Security Interest and shall act upon the instructions of the Collateral Agent without further consent
from the Grantor, and that such warehouseman, agent, bailee or processor further agrees to waive and release any Lien held by it with respect to such Inventory, whether arising by operation of law or otherwise. 
 (k) None of the Grantors will, without the Intercreditor Agent’s prior written consent pursuant to any Senior Collateral Document,
grant any extension of the time of payment of any Accounts included in the Article 9 Collateral, compromise, compound or settle the same for less than the full amount thereof, release, wholly or partly, any Person liable for the payment thereof
or allow any credit or discount whatsoever thereon, other than compromises, compoundings, settlements and collections made in the ordinary course of business or in accordance with the reasonable business judgment of such Grantor. 
 (l) The Grantors, at their own expense, shall maintain or cause to be maintained insurance covering physical loss or damage to the Inventory
and Equipment (x) in accordance with the requirements set forth in any agreement with respect to any Credit Facility or (y) after the Discharge of First-Priority Lien Obligation, in a manner and amount customary for companies in the same
industries as the Issuer. Subject to the Intercreditor Agreement, each Grantor irrevocably makes, constitutes and appoints the Collateral Agent (and all officers, employees or agents designated by the Collateral Agent) as such Grantor’s true
and lawful agent (and attorney-in-fact) for the purpose, upon the occurrence and during the continuance of an Event of Default, of making, settling and adjusting claims in respect of Article 9 Collateral under policies of insurance, endorsing
the name of such Grantor on any check, draft, instrument or other item of payment for the proceeds of such policies of insurance and for making all determinations and decisions with respect thereto. In the event that any Grantor at any time or times
shall fail to obtain or maintain any of the policies of insurance required under the first sentence of this Section 4.03(n) or to pay any premium in whole or part relating thereto, the Collateral Agent may, but is not obligated, without waiving
or releasing any obligation or liability of the Grantors hereunder or any Event of Default, in its sole reasonable discretion, obtain and maintain such policies of insurance and pay such premium and take any other actions with respect thereto as the
Collateral Agent deems

  

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advisable. All sums disbursed by the Collateral Agent in connection with this paragraph, including reasonable attorneys’ fees, court costs and other charges relating thereto, shall be
payable, within five days of demand, by the Grantors to the Collateral Agent and shall be additional Obligations secured hereby. 
 (m) Each Grantor shall maintain, in form and manner reasonably satisfactory to the Collateral Agent, records of its Chattel Paper and its books, records and documents evidencing or pertaining thereto. 
 SECTION 4.04. Other Actions. In order to insure the attachment, perfection and priority of, and the ability of the Collateral Agent
to enforce, the Security Interest, each Grantor agrees, in each case at such Grantor’s own expense, to take the following actions with respect to the following Article 9 Collateral: 
 (a) Instruments. If any Grantor shall at any time hold or acquire any Instruments with a value in excess of $500,000,
such Grantor shall forthwith endorse, assign and deliver the same to the Collateral Agent (or, prior to the Discharge of First-Priority Lien Obligations, to the Intercreditor Agent, acting as gratuitous bailee of the Collateral Agent), accompanied
by such undated instruments of transfer or assignment duly executed in blank as the Intercreditor Agent may from time to time reasonably request. 
 (b) Investment Property. Except to the extent otherwise provided in Article III, after the termination of the Existing Credit Agreement, if any Grantor shall at any time hold or acquire any
certificated securities, such Grantor shall forthwith endorse, assign and deliver the same to the Collateral Agent (or, prior to the Discharge of First-Priority Lien Obligations, to the Intercreditor Agent, acting as gratuitous bailee of the
Collateral Agent), accompanied by such instruments of transfer or assignment duly executed in blank as the Intercreditor Agent may from time to time specify pursuant to any Senior Collateral Document. If any securities now or hereafter acquired by
any Grantor are uncertificated and are issued to such Grantor or its nominee directly by the issuer thereof, such Grantor shall immediately notify the Collateral Agent (or, prior to the Discharge of First-Priority Lien Obligations, to the
Intercreditor Agent, acting as gratuitous bailee of the Collateral Agent) thereof and, at the Intercreditor Agent’s reasonable request and option pursuant to any Senior Collateral Document, following and during the continuance of an Event of
Default, pursuant to an agreement in form and substance reasonably satisfactory to the Intercreditor Agent, either (i) cause the issuer to agree to comply with instructions from the Intercreditor Agent as to such securities, without further
consent of any Grantor or such nominee, or (ii) arrange for the Intercreditor Agent to become the registered owner of the securities. If any securities, whether certificated or uncertificated, or other investment property now or hereafter
acquired by any Grantor are held by such Grantor or its nominee through a securities intermediary or commodity intermediary, such Grantor shall immediately notify the Collateral Agent thereof and, at the Intercreditor Agent’s request and option
pursuant to any Senior Collateral Document, following and during the continuance of an Event of Default, pursuant to an agreement in form

  

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and substance reasonably satisfactory to the Intercreditor Agent, either (i) cause such securities intermediary or commodity intermediary, as the case may be, to agree to comply with
entitlement orders or other instructions from the Collateral Agent to such securities intermediary as to such security entitlements or to apply any value distributed on account of any commodity contract as directed by the Collateral Agent to such
commodity intermediary, as the case may be, in each case without further consent of any Grantor, such nominee, or any other Person, or (ii) in the case of financial assets or other Investment Property held through a securities intermediary,
arrange for the Collateral Agent to become the entitlement holder with respect to such Investment Property, with the Grantor being permitted, only with the consent of the Collateral Agent, to exercise rights to withdraw or otherwise deal with such
Investment Property. The Collateral Agent agrees with each of the Grantors that the Collateral Agent shall not give any such entitlement orders or instructions or directions to any such issuer, securities intermediary or commodity intermediary, and
shall not withhold its consent to the exercise of any withdrawal or dealing rights by any Grantor, unless an Event of Default has occurred and is continuing, or, after giving effect to any such investment and withdrawal rights, would occur. The
provisions of this paragraph shall not apply to any financial assets credited to a securities account for which the Collateral Agent is the securities intermediary. 
 (c) Electronic Chattel Paper and Transferable Records. If any Grantor at any time holds or acquires an interest in any
electronic chattel paper or any “transferable record,” as that term is defined in Section 201 of the Federal Electronic Signatures in Global and National Commerce Act, or in Section 16 of the Uniform Electronic Transactions Act
as in effect in any relevant jurisdiction, with a value in excess of $500,000, such Grantor shall promptly notify the Collateral Agent thereof and, at the request of the Intercreditor Agent pursuant to any Senior Collateral Document, shall take such
action as the Intercreditor Agent may reasonably request pursuant to any Senior Collateral Document, to vest in the Intercreditor Agent (or, after the Discharge of First-Priority Lien Obligations, the Collateral Agent) control under New York
UCC Section 9-105 of such electronic chattel paper or control under Section 201 of the Federal Electronic Signatures in Global and National Commerce Act or, as applicable, Section 16 of the Uniform Electronic Transactions Act, as in
effect in such jurisdiction, of such transferable record. The Collateral Agent agrees with such Grantor that the Intercreditor Agent will arrange, pursuant to procedures reasonably satisfactory to the Intercreditor Agent pursuant to any Senior
Collateral Document and so long as such procedures will not result in the Collateral Agent’s loss of control, for the Grantor to make alterations to the electronic chattel paper or transferable record permitted under UCC Section 9-105 or,
as applicable, Section 201 of the Federal Electronic Signatures in Global and National Commerce Act or Section 16 of the Uniform Electronic Transactions Act for a party in control to allow without loss of control, unless an Event of
Default has occurred and is continuing or would occur after taking into account any action by such Grantor with respect to such electronic chattel paper or transferable record. 
  

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 (d) Letter-of-Credit Rights. Until the termination of the Existing
Credit Agreement, if any Grantor is at any time a beneficiary under a letter of credit now or hereafter issued in favor of such Grantor in an amount in excess of $500,000, such Grantor shall promptly notify the Collateral Agent thereof and, at the
request and option of the Intercreditor Agent pursuant to any Senior Collateral Document, such Grantor shall, pursuant to an agreement in form and substance reasonably satisfactory to the Intercreditor Agent, either (i) arrange for the issuer
and any confirmer of such letter of credit to consent to an assignment to the Collateral Agent of the proceeds of any drawing under such letter of credit or (ii) arrange for the Collateral Agent to become the transferee beneficiary of such
letter of credit, with the Collateral Agent agreeing, in each case, that the proceeds of any drawing under such letter of credit are to be paid to the applicable Grantor unless an Event of Default has occurred or is continuing. 
 (e) Commercial Tort Claims. Until the termination of the Existing Credit Agreement, if any Grantor shall at any time
hold or acquire a commercial tort claim in an amount reasonably estimated to exceed $2,500,000, the Grantor shall promptly notify the Collateral Agent thereof in a writing signed by such Grantor including a summary description of such claim and
grant to the Collateral Agent, for the ratable benefit of the Secured Parties, in such writing a security interest therein and in the proceeds thereof, all upon the terms of this Agreement, with such writing to be in form and substance reasonably
satisfactory to the Intercreditor Agent. 
 SECTION 4.05. Covenants Regarding Patent, Trademark and Copyright Collateral.
(a) Each Grantor agrees that it will not do any act or omit to do any act (and will exercise commercially reasonable efforts to prevent its licensees from doing any act or omitting to do any act) whereby any Patent that is material to the
conduct of such Grantor’s business would become invalidated or dedicated to the public, and agrees that it shall continue to mark any products covered by a Patent with the relevant patent number as necessary and sufficient in its reasonable
judgment to establish and preserve its material rights under applicable patent laws. 
 (b) Each Grantor (either itself or
through its licensees or its sublicensees) will, for each Trademark material to the conduct of such Grantor’s business, (i) maintain such Trademark in full force free from any claim of abandonment or invalidity for non-use, (ii) use
commercially reasonable efforts to maintain the quality of products and services offered under such Trademark, (iii) display such Trademark with notice of Federal or foreign registration (or, if such Trademark is unregistered, display such
Trademark with notice as required for unregistered Trademarks) to the extent necessary and sufficient to establish and preserve its maximum rights under applicable law and (iv) not knowingly use or knowingly permit the use of such Trademark in
any violation of any third party rights. 
 (c) Each Grantor (either itself or through its licensees or sublicensees) will, for
each work covered by a Copyright material to the conduct of such Grantor’s business, continue to publish, reproduce, display, adopt and distribute the work with appropriate copyright notice as necessary and sufficient in its reasonable judgment
to establish and preserve its material rights under applicable copyright laws. 
  

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 (d) Each Grantor shall notify the Collateral Agent promptly if it knows that any Patent,
Trademark or Copyright material to the conduct of its business could reasonably be expected to become abandoned, lost or dedicated to the public, or of any materially adverse determination or development (including the institution of, or any such
determination or development in, any proceeding in the United States Patent and Trademark Office, United States Copyright Office or any court or similar office of any country) regarding such Grantor’s ownership of any Patent, Trademark or
Copyright, its right to register the same, or its right to keep and maintain the same. 
 (e) Each Grantor will take all
reasonably necessary steps that are consistent with the practice in any proceeding before the United States Patent and Trademark Office, United States Copyright Office or any office or agency in any political subdivision of the United States or in
any other country or any political subdivision thereof, to maintain and pursue each registration or application that is material to the conduct of such Grantor’s business relating to the Patents, Trademarks and/or Copyrights (and to obtain the
relevant grant or registration) and to maintain each issued Patent and each registration of the Trademarks and Copyrights that is material to the conduct of any Grantor’s business, including timely filings of applications for renewal,
affidavits of use, affidavits of incontestability and payment of maintenance fees, and, if consistent with good business judgment, to initiate opposition, interference and cancellation proceedings against third parties. 
 (f) In the event that any Grantor knows that any Article 9 Collateral consisting of a Patent, Trademark or Copyright material to the
conduct of any Grantor’s business has been or is about to be infringed, misappropriated or diluted by a third party, such Grantor promptly shall notify the Collateral Agent and shall, if consistent with good business judgment, promptly sue for
infringement, misappropriation or dilution and to recover any and all damages for such infringement, misappropriation or dilution (and take any actions required by applicable law prior to instituting such suit), and take such other actions as are
appropriate under the circumstances to protect such Article 9 Collateral. Nothing in this Agreement shall prevent any Grantor from discontinuing the use or maintenance of any Article 9 Collateral consisting of a Patent, Trademark or
Copyright, or require any Grantor to pursue any claim of infringement, misappropriation or dilution, if (x) such Grantor so determines in its good business judgment and (y) it is not prohibited by the Indenture. 
 (g) Upon and during the continuance of an Event of Default, each Grantor shall, at the request of the Intercreditor Agent pursuant to any
Senior Collateral Document, use its commercially reasonable efforts to obtain all requisite consents or approvals by the licensor of each Copyright, License, Patent License or Trademark License to effect the assignment of all such Grantor’s
right, title and interest thereunder to the Collateral Agent or its designee. 
  

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 SECTION 4.06. Cash Management System. (a) The Grantors shall ensure that the
Concentration Accounts are subject to the terms of a deposit account control agreement in a form reasonably satisfactory to the Intercreditor Agent and the Issuer within 120 days of the Issue Date. In addition, the Grantors shall ensure that any
Deposit Account or securities or other investment account that becomes subject to an account control agreement with the Intercreditor Agent is subject to the terms of the same account control agreement or a separate account control agreement in
substantially the same form as the agreement entered into with the Intercreditor Agent with the Collateral Agent at the same time. 
 (b) Following the Discharge of First-Priority Lien Obligations, the Grantors shall not, without the prior written consent of the Collateral Agent, the Grantors shall not change their system of deposit accounts and lockbox accounts or change
their cash management systems, in each case in a manner materially adverse to the Secured Parties. 
 ARTICLE V 
 Remedies 
 SECTION
5.01. Remedies Upon Default. Upon the occurrence and during the continuance of an Event of Default, each Grantor agrees to deliver each item of Collateral to the Collateral Agent on demand, and it is agreed that the Collateral Agent shall
have the right to take any of or all the following actions at the same or different times: (a) with respect to any Article 9 Collateral consisting of Intellectual Property, on demand, to cause the Security Interest to become an assignment,
transfer and conveyance of any of or all such Article 9 Collateral by the applicable Grantors to the Collateral Agent, for the ratable benefit of the Secured Parties, or to license or sublicense, whether general, special or otherwise, and whether on
an exclusive or nonexclusive basis, any such Article 9 Collateral throughout the world on such terms and conditions and in such manner as the Collateral Agent shall determine (other than in violation of any then-existing licensing arrangements to
the extent that waivers cannot be obtained), and (b) with or without legal process and with or without prior notice or demand for performance, to take possession of the Article 9 Collateral and without liability for trespass to enter any
premises where the Article 9 Collateral may be located for the purpose of taking possession of or removing the Article 9 Collateral and, generally, to exercise any and all rights afforded to a secured party under the Uniform Commercial Code or other
applicable law. Without limiting the generality of the foregoing, each Grantor agrees that the Collateral Agent shall have the right, subject to the mandatory requirements of applicable law, to sell or otherwise dispose of all or any part of the
Collateral at a public or private sale or at any broker’s board or on any securities exchange, for cash, upon credit or for future delivery as the Collateral Agent shall deem appropriate. After the termination of the Existing Credit Agreement,
the Collateral Agent shall be authorized at any such sale of securities (if it deems it advisable to do so) to restrict the prospective bidders or purchasers to Persons who will represent and agree that they are purchasing the Collateral for their
own account for investment and not with a view to the distribution or sale thereof, and upon consummation of any such sale the

  

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Collateral Agent shall have the right to assign, transfer and deliver to the purchaser or purchasers thereof the Collateral so sold. Each such purchaser at any sale of Collateral shall hold the
property sold absolutely, free from any claim or right on the part of any Grantor, and each Grantor hereby waives (to the extent permitted by law) all rights of redemption, stay and appraisal that such Grantor now has or may at any time in the
future have under any rule of law or statute now existing or hereafter enacted. 
 The Collateral Agent shall give the
applicable Grantors 10 days’ written notice (which each Grantor agrees is reasonable notice within the meaning of Section 9-611 of the New York UCC or its equivalent in other jurisdictions) of the Collateral Agent’s
intention to make any sale of Collateral. Such notice, in the case of a public sale, shall state the time and place for such sale and, in the case of a sale at a broker’s board or on a securities exchange, shall state the board or exchange at
which such sale is to be made and the day on which the Collateral, or portion thereof, will first be offered for sale at such board or exchange. Any such public sale shall be held at such time or times within ordinary business hours and at such
place or places as the Collateral Agent may fix and state in the notice (if any) of such sale. At any such sale, the Collateral, or portion thereof, to be sold may be sold in one lot as an entirety or in separate parcels, as the Collateral Agent may
determine in its sole and absolute discretion. The Collateral Agent shall not be obligated to make any sale of any Collateral if it shall determine not to do so, regardless of the fact that notice of sale of such Collateral shall have been given.
The Collateral Agent may, without notice or publication, adjourn any public or private sale or cause the same to be adjourned from time to time by announcement at the time and place fixed for sale, and such sale may, without further notice, be made
at the time and place to which the same was so adjourned. In case any sale of all or any part of the Collateral is made on credit or for future delivery, the Collateral so sold may be retained by the Collateral Agent until the sale price is paid by
the purchaser or purchasers thereof, but the Collateral Agent and the other Secured Parties shall not incur any liability in case any such purchaser or purchasers shall fail to take up and pay for the Collateral so sold and, in case of any such
failure, such Collateral may be sold again upon like notice. At any public (or, to the extent permitted by law, private) sale made pursuant to this Agreement, any Secured Party may bid for or purchase, free (to the extent permitted by law) from any
right of redemption, stay, valuation or appraisal on the part of any Grantor (all said rights being also hereby waived and released to the extent permitted by law), the Collateral or any part thereof offered for sale and may make payment on account
thereof by using any claim then due and payable to such Secured Party from any Grantor as a credit against the purchase price, and such Secured Party may, upon compliance with the terms of sale, hold, retain and dispose of such property without
further accountability to any Grantor therefor. For purposes hereof, a written agreement to purchase the Collateral or any portion thereof shall be treated as a sale thereof; the Collateral Agent shall be free to carry out such sale pursuant to such
agreement and no Grantor shall be entitled to the return of the Collateral or any portion thereof subject thereto, notwithstanding the fact that after the Collateral Agent shall have entered into such an agreement, all Events of Default shall have
been remedied and the Obligations paid in full (in which case the applicable Grantors shall be entitled to the proceeds of any such sale pursuant to Section 5.02 hereof). As an alternative to exercising the power of sale herein conferred upon
it,

  

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the Collateral Agent may proceed by a suit or suits at law or in equity to foreclose this Agreement and to sell the Collateral or any portion thereof pursuant to a judgment or decree of a court
or courts having competent jurisdiction or pursuant to a proceeding by a court-appointed receiver. Any sale pursuant to the provisions of this Section 5.01 shall be deemed to conform to the commercially reasonable standards as provided in
Section 9-610(b) of the New York UCC or its equivalent in other jurisdictions. 
 SECTION 5.02. Application of
Proceeds. The Collateral Agent shall, subject to the Intercreditor Agreement, apply the proceeds of any collection or sale of Collateral pursuant to this Article V, including any Collateral consisting of cash, as follows: 
 FIRST, to the payment of all costs and expenses incurred by the Collateral Agent in connection with such collection or sale
or otherwise in connection with this Agreement, any other Indenture Document or any of the Obligations, including all court costs and the fees and expenses of its agents and legal counsel, the repayment of all advances made by the Collateral Agent
hereunder or under any other Indenture Document on behalf of any Grantor and any other costs or expenses incurred in connection with the exercise of any right or remedy hereunder or under any other Indenture Document; 
 SECOND, to the payment in full of the Obligations (the amounts so applied to be distributed among the Secured Parties pro
rata in accordance with the amounts of the Obligations owed to them on the date of any such distribution); and 
 THIRD, to the Grantors, their successors or assigns, or as a court of competent jurisdiction may otherwise direct. 
 The Collateral
Agent shall have sole and absolute discretion as to the time of application of any such proceeds, moneys or balances in accordance with this Agreement. Upon any sale of Collateral by the Collateral Agent (including pursuant to a power of sale
granted by statute or under a judicial proceeding), the receipt of the Collateral Agent or of the officer making the sale shall be a sufficient discharge to the purchaser or purchasers of the Collateral so sold and such purchaser or purchasers shall
not be obligated to see to the application of any part of the purchase money paid over to the Collateral Agent or such officer or be answerable in any way for the misapplication thereof. 
 SECTION 5.03. Grant of License to Use Intellectual Property. For the purpose of enabling the Collateral Agent to exercise rights and
remedies under this Agreement in accordance with, and to the extent consistent with, the terms of the Intercreditor Agreement at such time as the Collateral Agent shall be lawfully entitled to exercise such rights and remedies, each Grantor hereby
grants to the Collateral Agent an irrevocable, nonexclusive license (exercisable without payment of royalty or other compensation to the Grantors) to use, license or sublicense any of the Article 9 Collateral consisting of Intellectual Property
now owned or hereafter acquired by such Grantor, and wherever the same may be located, and including in such license reasonable access to all

  

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media in which any of the licensed items may be recorded or stored and to all computer software and programs used for the compilation or printout thereof. The use of such license by the
Collateral Agent shall be exercised, at the option of the Collateral Agent, only upon the occurrence and during the continuance of an Event of Default, provided that any license, sublicense or other transaction entered into by the Collateral
Agent in accordance herewith shall be binding upon the Grantors notwithstanding any subsequent cure of an Event of Default. 
 SECTION 5.04. Securities Act. In view of the position of the Grantors in relation to the Pledged Collateral, or because of other current or future circumstances, a question may arise under the Securities Act of 1933, as now or
hereafter in effect, or any similar statute hereafter enacted analogous in purpose or effect (such Act and any such similar statute as from time to time in effect being called the “Federal Securities Laws”) with respect to any
disposition of the Pledged Collateral permitted hereunder. Each Grantor understands that compliance with the Federal Securities Laws might very strictly limit the course of conduct of the Collateral Agent if the Collateral Agent were to attempt to
dispose of all or any part of the Pledged Collateral, and might also limit the extent to which or the manner in which any subsequent transferee of any Pledged Collateral could dispose of the same. Similarly, there may be other legal restrictions or
limitations affecting the Collateral Agent in any attempt to dispose of all or part of the Pledged Collateral under applicable Blue Sky or other state securities laws or similar laws analogous in purpose or effect. Each Grantor recognizes that in
light of such restrictions and limitations the Collateral Agent may, with respect to any sale of the Pledged Collateral, limit the purchasers to those who will agree, among other things, to acquire such Pledged Collateral for their own account, for
investment, and not with a view to the distribution or resale thereof. Each Grantor acknowledges and agrees that in light of such restrictions and limitations, the Collateral Agent, in its sole and absolute discretion (a) may proceed to make
such a sale whether or not a registration statement for the purpose of registering such Pledged Collateral or part thereof shall have been filed under the Federal Securities Laws and (b) may approach and negotiate with a single potential
purchaser to effect such sale. Each Grantor acknowledges and agrees that any such sale might result in prices and other terms less favorable to the seller than if such sale were a public sale without such restrictions. In the event of any such sale,
the Collateral Agent shall incur no responsibility or liability for selling all or any part of the Pledged Collateral at a price that the Collateral Agent, in its sole and absolute discretion, may in good faith deem reasonable under the
circumstances, notwithstanding the possibility that a substantially higher price might have been realized if the sale were deferred until after registration as aforesaid or if more than a single purchaser were approached. The provisions of this
Section 5.04 will apply notwithstanding the existence of a public or private market upon which the quotations or sales prices may exceed substantially the price at which the Collateral Agent sells. 
  

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 ARTICLE VI 
 [Intentionally Omitted] 
 ARTICLE VII 
 Miscellaneous 
 SECTION 7.01. Notices. All communications and notices hereunder shall (except as otherwise expressly permitted in this Agreement) be in writing and given as provided in Section 12.02 of the Indenture, provided that any
communication or notice hereunder from the Collateral Agent to any Grantor upon the occurrence and during the continuance of an Event of Default may be given by telephone if promptly confirmed in writing. All communications and notices hereunder to
any Subsidiary Guarantor shall be given to it in care of the Issuer as provided in Section 12.02 of the Indenture. 
 SECTION 7.02. Waivers; Amendment. (a) No failure or delay by any Secured Party in exercising any right or power hereunder or under any other Indenture Document shall operate as a waiver thereof, nor shall any single or partial
exercise of any such right or power, or any abandonment or discontinuance of steps to enforce such a right or power, preclude any other or further exercise thereof or the exercise of any other right or power. The rights and remedies of the Secured
Parties hereunder and under the other Indenture Documents are cumulative and are not exclusive of any rights or remedies that they would otherwise have. No waiver of any provision in this Agreement or consent to any departure by any Grantor
therefrom shall in any event be effective unless the same shall be permitted by paragraph (b) of this Section 7.02, and then such waiver or consent shall be effective only in the specific instance and for the purpose for which given. No
notice or demand on any Grantor in any case shall entitle any Grantor to any other or further notice or demand in similar or other circumstances. 
 (b) Neither this Agreement nor any provision hereof may be waived, amended or modified except pursuant to an agreement or agreements in writing entered into by the Collateral Agent and the Grantors with
respect to which such waiver, amendment or modification is to apply, subject to any consent required in accordance with the Indenture. 
 SECTION 7.03. Collateral Agent’s Fees and Expenses; Indemnification. (a) The parties hereto agree that the Collateral Agent shall be entitled to reimbursement of its reasonable expenses incurred hereunder as provided in
Section 11.11 of the Indenture. 
 (b) Without limitation of its indemnification obligations under the other Indenture
Documents, each Grantor jointly and severally agrees to indemnify the Collateral Agent (as defined in the Indenture) against, and hold each Collateral Agent harmless from, any and all losses, claims, damages, liabilities and related out-of-pocket
expenses, including the fees, charges and disbursements of any counsel for any Collateral Agent, incurred by or asserted against any Collateral Agent by any third party or by any

  

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Grantor arising out of, in connection with, or as a result of, the execution, delivery or performance of this Agreement or any actual or prospective claim, litigation, investigation or proceeding
relating to any of the foregoing agreements or instruments contemplated hereby, or to the Collateral, whether or not the Collateral Agent is a party thereto, provided that such indemnity shall not, as to any Collateral Agent, be available to
the extent that such losses, claims, damages, liabilities or related out-of-pocket expenses are determined by a court of competent jurisdiction to have resulted from the gross negligence or wilful misconduct of such Collateral Agent or any of its
Related Parties. 
 (c) Any such amounts payable as provided hereunder shall be additional Obligations secured hereby and by the
other Security Documents. The provisions of this Section 7.03 shall remain operative and in full force and effect regardless of the termination of this Agreement or any other Indenture Document, the consummation of the transactions contemplated
hereby, the repayment of any of the Obligations, the invalidity or unenforceability of any term or provision of this Agreement or any other Indenture Document, or any investigation made by or on behalf of the Collateral Agent or any other Secured
Party. All amounts due under this Section 7.03 shall be payable on written demand therefor. 
 SECTION 7.04. Successors
and Assigns. Whenever in this Agreement any of the parties hereto is referred to, such reference shall be deemed to include the permitted successors and assigns of such party; and all covenants, promises and agreements by or on behalf of any
Grantor or the Collateral Agent that are contained in this Agreement shall bind and inure to the benefit of their respective successors and assigns and shall inure to the benefit of the other Secured Parties and their respective successors and
assigns. 
 SECTION 7.05. Survival of Agreement. All covenants, agreements, representations and warranties made by the
Grantors in the Indenture Documents and in the certificates or other instruments prepared or delivered in connection with or pursuant to this Agreement or any other Indenture Document shall be considered to have been relied upon by the Holders and
shall survive the execution and delivery of the Indenture Documents, regardless of any investigation made by any Holders or on its behalf and notwithstanding that the Collateral Agent may have had notice or knowledge of any Default or incorrect
representation or warranty at any time and shall continue in full force and effect as long as the principal of or any accrued interest on any Security or any fee or any other amount payable under any Indenture Document is outstanding. 
 SECTION 7.06. Counterparts; Effectiveness; Several Agreement. This Agreement may be executed in counterparts, each of which shall
constitute an original but all of which, when taken together, shall constitute single contract. Delivery of an executed signature page to this Agreement by facsimile transmission shall be as effective as delivery of a manually signed counterpart of
this Agreement. This Agreement shall become effective as to any Grantor when a counterpart hereof executed on behalf of such Grantor shall have been delivered to the Collateral Agent and a counterpart hereof shall have been executed on behalf of the
Collateral Agent, and thereafter shall be binding upon such Grantor and the Collateral Agent and their respective permitted successors and

  

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assigns, and shall inure to the benefit of such Grantor, the Collateral Agent and the other Secured Parties and their respective successors and assigns, except that no Grantor shall have the
right to assign or transfer its rights or obligations hereunder or any interest in this Agreement or in the Collateral (and any such assignment or transfer shall be void) except as contemplated by this Agreement or the Indenture. This Agreement
shall be construed as a separate agreement with respect to each Grantor and may be amended, modified, supplemented, waived or released with respect to any Grantor without the approval of any other Grantor and without affecting the obligations of any
other Grantor hereunder. 
 SECTION 7.07. Severability. Any provision in this Agreement held to be invalid, illegal or
unenforceable in any jurisdiction shall, as to such jurisdiction, be ineffective to the extent of such invalidity, illegality or unenforceability without affecting the validity, legality and enforceability of the remaining provisions hereof; the
invalidity of a particular provision in a particular jurisdiction shall not invalidate such provision in any other jurisdiction. The parties shall endeavor in good-faith negotiations to replace the invalid, illegal or unenforceable provisions with
valid provisions the economic effect of which comes as close as possible to that of the invalid, illegal or unenforceable provisions. 
 SECTION 7.08. Right of Set-Off. If an Event of Default shall have occurred and be continuing, each Secured Party is hereby authorized at any time and from time to time, to the fullest extent permitted by law, to set off and apply any
and all deposits (general or special, time or demand, provisional or final) at any time held and other obligations at any time owing by such Secured Party to or for the credit or the account of any Grantor against any of and all the obligations of
such Grantor now or hereafter existing under this Agreement owed to such Secured Party, irrespective of whether or not such Secured Party shall have made any demand under this Agreement and although such obligations may be unmatured. The rights of
each Secured Party under this Section 7.08 are in addition to other rights and remedies (including other rights of set-off) which such Secured Party may have. 
 SECTION 7.09. Governing Law; Jurisdiction; Consent to Service of Process. (a) This Agreement shall be construed in accordance with and governed by the law of the State of New York. 

(b) Each of the parties hereto hereby irrevocably and unconditionally submits, for itself and its property, to the nonexclusive
jurisdiction of the Supreme Court of the State of New York sitting in New York County and of the United States District Court of the Southern District of New York, and any appellate court from any thereof, in any action or proceeding arising out of
or relating to this Agreement or any other Loan Document, or for recognition or enforcement of any judgment, and each of the parties hereto hereby irrevocably and unconditionally agrees that all claims in respect of any such action or proceeding may
be heard and determined in such New York State or, to the extent permitted by law, in such Federal court. Each of the parties hereto agrees that a final judgment in any such action or proceeding shall be conclusive and may be enforced in other
jurisdictions by suit on the judgment or in any other manner provided

  

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by law. Nothing in this Agreement or any other Loan Document shall affect any right that the Collateral Agent, the Issuing Bank, any Lender or any Loan Party may otherwise have to bring any
action or proceeding relating to this Agreement or any other Loan Document in the courts of any jurisdiction. 
 (c) Each of the
Grantors hereby irrevocably and unconditionally waives, to the fullest extent it may legally and effectively do so, any objection that it may now or hereafter have to the laying of venue of any suit, action or proceeding arising out of or relating
to this Agreement or any other Indenture Document in any court referred to in paragraph (b) of this Section 7.09. Each of the parties hereto hereby irrevocably waives, to the fullest extent permitted by law, the defense of an inconvenient
forum to the maintenance of such action or proceeding in any such court. 
 (d) Each party to this Agreement irrevocably
consents to service of process in the manner provided for notices in Section 7.01. Nothing in this Agreement or any other Indenture Document will affect the right of any party to this Agreement to serve process in any other manner permitted by
law. 
 SECTION 7.10. WAIVER OF JURY TRIAL. EACH PARTY HERETO HEREBY WAIVES, TO THE FULLEST EXTENT PERMITTED BY
APPLICABLE LAW, ANY RIGHT IT MAY HAVE TO A TRIAL BY JURY IN ANY LEGAL PROCEEDING DIRECTLY OR INDIRECTLY ARISING OUT OF OR RELATING TO THIS AGREEMENT, ANY OTHER LOAN DOCUMENT OR THE TRANSACTIONS CONTEMPLATED HEREBY (WHETHER BASED ON CONTRACT, TORT OR
ANY OTHER THEORY). EACH PARTY HERETO (A) CERTIFIES THAT NO REPRESENTATIVE, AGENT OR ATTORNEY OF ANY OTHER PARTY HAS REPRESENTED, EXPRESSLY OR OTHERWISE, THAT SUCH OTHER PARTY WOULD NOT, IN THE EVENT OF LITIGATION, SEEK TO ENFORCE THE FOREGOING
WAIVER AND (B) ACKNOWLEDGES THAT IT AND THE OTHER PARTIES HERETO HAVE BEEN INDUCED TO ENTER INTO THIS AGREEMENT BY, AMONG OTHER THINGS, THE MUTUAL WAIVERS AND CERTIFICATIONS IN THIS SECTION 7.10. 
 SECTION 7.11. Headings. Article and Section headings and the Table of Contents used in this Agreement are for convenience of
reference only, are not part of this Agreement and are not to affect the construction of, or to be taken into consideration in interpreting, this Agreement. 
 SECTION 7.12. Security Interest Absolute. All rights of the Collateral Agent hereunder, the Security Interest, the grant of a security interest in the Pledged Collateral and all obligations of each
Grantor hereunder shall be absolute and unconditional irrespective of (a) any lack of validity or enforceability of the Indenture, any other Indenture Document, any agreement with respect to any of the Obligations or any other agreement or
instrument relating to any of the foregoing, (b) any change in the time, manner or place of payment of, or in any other term of, all or any of the Obligations, or any other amendment or waiver of or any consent to any departure from the
Indenture, any other Indenture Document or any other agreement or instrument,

  

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(c) any exchange, release or non-perfection of any Lien on other collateral, or any release or amendment or waiver of or consent under or departure from any guarantee, securing or
guaranteeing all or any of the Obligations, or (d) any other circumstance that might otherwise constitute a defense available to, or a discharge of, any Grantor in respect of the Obligations or this Agreement. 
 SECTION 7.13. Termination or Release. (a) This Agreement shall terminate and the Security Interest and all other security
interests granted hereby shall be automatically released when all the Obligations have been paid in full. 
 (b) A Subsidiary
Guarantor shall automatically be released from its obligations hereunder and the Security Interest in the Collateral of such Subsidiary Guarantor shall be automatically released upon the consummation of any transaction permitted by the Indenture as
a result of which such Subsidiary Guarantor ceases to be a Subsidiary. 
 (c) Upon any sale or other transfer by any Grantor of
any Collateral that is permitted under the Indenture, or upon the effectiveness of any written consent to the release of the security interest granted hereby in any Collateral pursuant to the Indenture, the security interest in such Collateral shall
be automatically released. 
 (d) In connection with any termination or release pursuant to paragraph (a), (b) or
(c) of this Section 7.13, the Collateral Agent shall execute and deliver to any Grantor, at such Grantor’s expense, all documents that such Grantor shall reasonably request to evidence such termination or release. Any execution and
delivery of documents pursuant to this Section 7.13 shall be without recourse to or warranty by the Collateral Agent. 
 SECTION 7.14. Additional Subsidiaries. Pursuant to Section 4.14 of the Indenture, each Subsidiary of a Grantor that was not in existence or not a Subsidiary on the date of the Indenture and is not a Foreign Subsidiary may be
required to enter in this Agreement as a Subsidiary Guarantor upon becoming such a Subsidiary. Upon execution and delivery by the Collateral Agent and a Subsidiary of an instrument in the form of Exhibit I hereto, such Subsidiary shall become a
Subsidiary Guarantor hereunder with the same force and effect as if originally named as a Subsidiary Guarantor in this Agreement. The execution and delivery of any such instrument shall not require the consent of any other Grantor hereunder. The
rights and obligations of each Grantor hereunder shall remain in full force and effect notwithstanding the addition of any new Grantor as a party to this Agreement. 
 SECTION 7.15. Collateral Agent Appointed Attorney-in-Fact. Each Grantor hereby appoints the Collateral Agent the attorney-in-fact of such Grantor for the purpose of carrying out the provisions of
this Agreement and taking any action and executing any instrument that the Collateral Agent may deem necessary or advisable to accomplish the purposes hereof, which appointment is irrevocable and coupled with an interest. Without limiting the
generality of the foregoing, the Collateral Agent shall have the right, upon the occurrence and during the continuance of an Event of Default, with

  

 32 

 
full power of substitution either in the Collateral Agent’s name or in the name of such Grantor (a) to receive, endorse, assign and/or deliver any and all notes, acceptances, checks,
drafts, money orders or other evidences of payment relating to the Collateral or any part thereof; (b) to demand, collect, receive payment of, give receipt for and give discharges and releases of all or any of the Collateral; (c) to sign
the name of any Grantor on any invoice or bill of lading relating to any of the Collateral; (d) to send verifications of Accounts Receivable to any Account Debtor; (e) to commence and prosecute any and all suits, actions or proceedings at
law or in equity in any court of competent jurisdiction to collect or otherwise realize on all or any of the Collateral or to enforce any rights in respect of any Collateral; (f) to settle, compromise, compound, adjust or defend any actions,
suits or proceedings relating to all or any of the Collateral; (g) to notify, or to require any Grantor to notify, Account Debtors to make payment directly to the Collateral Agent; and (h) to use, sell, assign, transfer, pledge, make any
agreement with respect to or otherwise deal with all or any of the Collateral, and to do all other acts and things necessary to carry out the purposes of this Agreement, as fully and completely as though the Collateral Agent were the absolute owner
of the Collateral for all purposes, provided that nothing in this Agreement contained shall be construed as requiring or obligating the Collateral Agent to make any commitment or to make any inquiry as to the nature or sufficiency of any
payment received by the Collateral Agent, or to present or file any claim or notice, or to take any action with respect to the Collateral or any part thereof or the moneys due or to become due in respect thereof or any property covered thereby. The
Collateral Agent and the other Secured Parties shall be accountable only for amounts actually received as a result of the exercise of the powers granted to them in this Agreement, and neither they nor their officers, directors, employees or agents
shall be responsible to any Grantor for any act or failure to act hereunder, except for their own gross negligence or wilful misconduct. 
 SECTION 7.16. Intercreditor Agreement Governs. Notwithstanding anything herein to the contrary, (i) the lien and security interest granted to the Collateral Agent, for the ratable benefit of
the Secured Parties, pursuant to this Agreement are expressly subject to and subordinate to the liens and security interests granted to (a) JPMorgan Chase Bank, N.A., as collateral agent (and its permitted successors) pursuant to the Guarantee
and Collateral Agreement dated as of August 20, 2004 (as amended, restated, supplemented or otherwise modified from time to time), by and among U.S. Oncology Holdings, Inc., the Issuer, the other “Grantors” named therein, JPMorgan
Chase Bank, N.A., as collateral agent, and the other parties thereto (and any similar agreement entered into pursuant to a Refinancing of the First-Priority Lien Obligations secured thereby as permitted under the Indenture) or (b) any agent or
trustee for any other Senior Lenders (as defined in the Intercreditor Agreement), in the case of clause (a) and (b), to the extent provided in the Intercreditor Agreement and (ii) the exercise of any right or remedy by the Collateral Agent
and the other Secured Parties hereunder are subject to the limitations and provisions of the Intercreditor Agreement. In the event of any conflict or inconsistency between the Intercreditor Agreement and this Agreement, the provisions of the
Intercreditor Agreement shall control. 
 SECTION 7.17. Mortgages. In the event that any of the Collateral hereunder is
also subject to a valid and enforceable Lien under the terms of a Mortgage

  

 33 

 
and the terms thereof are inconsistent with the terms of this Agreement, then with respect to such Collateral, the terms of such Mortgage shall control in the case of Fixtures and real estate
leases, letting and licenses of, and contracts and agreements relating to the lease of, real property, and the terms of this Agreement shall control in the case of all other Collateral. 
 SECTION 7.18. Intercreditor Agent. The parties hereto agree that the Intercreditor Agent shall have no obligation whatsoever to or
fiduciary relationship in respect of the Collateral Agent under this Agreement and the Collateral Agent hereby waives and releases the Intercreditor Agent from all claims and liabilities arising pursuant to the Intercreditor Agent’s role under
this Agreement. 
 [Signature Pages to Follow] 
  

 34 

 IN WITNESS WHEREOF, the parties hereto have duly executed this Agreement as of the day and
year first above written. 
  

							
	US ONCOLOGY, INC.
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Chief Financial Officer and Executive Vice President

  

							
	 ACCESSMED HOLDINGS, LLC,
 as a Subsidiary Guarantor,

		
		 	 By: Physician Reliance Network, LLC,
 its sole member

			
		 	 By: 
	 	 /s/ Michael A. Sicuro

		 		 	 Name:
	 	Michael A. Sicuro
		 		 	 Title:
	 	Vice President and Treasurer

  

							
	 ACCESSMED, LLC, as a Subsidiary Guarantor,

		
		 	 By: Physician Reliance Network, LLC,
 its sole member

			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	 AOR HOLDING COMPANY OF INDIANA, LLC,
 as a Subsidiary Guarantor,

		
		 	 By: Physician Reliance Network, LLC,
 its sole member

			
		 	 By:
	 	 /s/ Michael A. Sicuro

		 		 	 Name:
	 	Michael A. Sicuro
		 		 	 Title:
	 	Vice President and Treasurer

  

 35 

							
	AOR MANAGEMENT COMPANY OF ARIZONA, LLC, as a Subsidiary Guarantor,
		
		 	 By: Physician Reliance Network, LLC,
 its sole member

			
		 	 By:
	 	 /s/ Michael A. Sicuro

		 		 	 Name:
	 	Michael A. Sicuro
		 		 	 Title:
	 	Vice President and Treasurer

  

							
	AOR MANAGEMENT COMPANY OF INDIANA, LLC, as a Subsidiary Guarantor,
		
		 	 By: Physician Reliance Network, LLC,
 its sole member

			
		 	 By:
	 	 /s/ Michael A. Sicuro

		 		 	 Name:
	 	Michael A. Sicuro
		 		 	 Title:
	 	Vice President and Treasurer

  

							
	AOR MANAGEMENT COMPANY OF MISSOURI, LLC, as a Subsidiary Guarantor,
		
		 	 By: Physician Reliance Network, LLC,
 its sole member

			
		 	 By:
	 	 /s/ Michael A. Sicuro

		 		 	 Name:
	 	Michael A. Sicuro
		 		 	 Title:
	 	Vice President and Treasurer

  

							
	AOR MANAGEMENT COMPANY OF OKLAHOMA, LLC, as a Subsidiary Guarantor,
		
		 	 By: Physician Reliance Network, LLC,
 its sole member

			
		 	 By:
	 	 /s/ Michael A. Sicuro

		 		 	 Name:
	 	Michael A. Sicuro
		 		 	 Title:
	 	Vice President and Treasurer

  

 36 

							
	AOR MANAGEMENT COMPANY OF PENNSYLVANIA, LLC, as a Subsidiary Guarantor,
		
		 	 By: Physician Reliance Network, LLC,
 its sole member

			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	 AOR MANAGEMENT COMPANY OF VIRGINIA, LLC, as a Subsidiary Guarantor,

		
		 	 By: Physician Reliance Network, LLC,
 its sole member

			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	AOR OF INDIANA MANAGEMENT PARTNERSHIP, as a Subsidiary Guarantor,
		
		 	By: AOR Management Company of Indiana, LLC, its general partner
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer
		
		 	and
		
		 	By: AOR Holding Company of Indiana, LLC, its general partner
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

 37 

							
	AOR OF TEXAS MANAGEMENT, LLC, as a Subsidiary Guarantor,
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	AOR REAL ESTATE, LLC, as a Subsidiary Guarantor,
		
		 	By: Physician Reliance Network, LLC, its sole member
			
		 	 By:
	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	AOR SYNTHETIC REAL ESTATE, LLC, as a Subsidiary Guarantor,
		
		 	By: Physician Reliance Network, LLC, its sole member
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	AORT HOLDING COMPANY, INC., as a Subsidiary Guarantor,
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	GREENVILLE RADIATION CARE, INC., as a Subsidiary Guarantor,
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

 38 

							
	INNOVENT ONCOLOGY, LLC, as a Subsidiary Guarantor,
		
		 	By: Physician Reliance Network, LLC, its sole member
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	IOWA PHARMACEUTICAL SERVICES, LLC, as a Subsidiary Guarantor,
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	NEBRASKA PHARMACEUTICAL SERVICES, LLC, as a Subsidiary Guarantor,
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	 NEW MEXICO PHARMACEUTICAL SERVICES, LLC, as a Subsidiary Guarantor,

			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	NORTH CAROLINA PHARMACEUTICAL SERVICES, LLC, as a Subsidiary Guarantor,
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

 39 

							
	ONCOLOGY RX CARE ADVANTAGE, LP, as a Subsidiary Guarantor,
		
		 	By: US Oncology Corporate, Inc., its general partner
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer
	
	ONCOLOGY TODAY, LP, as a Subsidiary Guarantor,
		
		 	By: US Oncology Corporate, Inc., its general partner
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer
	
	PHYSICIAN RELIANCE, LLC, as a Subsidiary Guarantor,
		
		 	By: Physician Reliance Network, LLC, its sole member
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer
	
	PHYSICIAN RELIANCE NETWORK, LLC, as a Subsidiary Guarantor,
		
		 	By: US Oncology, Inc., its sole member
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

 40 

							
	RMCC CANCER CENTER, LLC, as a Subsidiary Guarantor,
		
		 	By: Physician Reliance Network, LLC, its sole member
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer
	
	SELECTPLUS ONCOLOGY, LLC, as a Subsidiary Guarantor,
		
		 	By: Physician Reliance Network, LLC, its sole member
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer
	
	ST. LOUIS PHARMACEUTICAL SERVICES, LLC, as a Subsidiary Guarantor,
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer
	
	TEXAS PHARMACEUTICAL SERVICES, LLC, as a Subsidiary Guarantor,
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer
	
	UNITY ONCOLOGY, LLC, as a Subsidiary Guarantor,
		
		 	By: Physician Reliance Network, LLC, its sole member
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

 41 

							
	TOPS PHARMACY SERVICES, INC., as a Subsidiary Guarantor,
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer
	
	US ONCOLOGY CLINICAL DEVELOPMENT, LLC, as a Subsidiary Guarantor,
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer
	
	US ONCOLOGY CORPORATE, INC., as a Subsidiary Guarantor,
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer
	
	US ONCOLOGY INTEGRATED SOLUTIONS, LP, as a Subsidiary Guarantor,
		
		 	By: US Oncology Corporate, Inc., its general partner
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer
	
	US ONCOLOGY PHARMACEUTICAL SERVICES, LLC, as a Subsidiary Guarantor,
			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

 42 

							
	 US ONCOLOGY REIMBURSEMENT SOLUTIONS, LLC, as a Subsidiary
 Guarantor,

		
		 	 By: Physician Reliance Network, LLC,
 its sole member

			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer
	
	 US ONCOLOGY RESEARCH, LLC, as a
 Subsidiary Guarantor,

		
		 	 By: Physician Reliance Network, LLC,
 its sole member

			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer
	
	 US ONCOLOGY SPECIALTY, LP, as a
 Subsidiary Guarantor,

		
		 	 By: US Oncology Corporate, Inc., its
 general partner

			
		 	By:	 	 /s/ Michael A. Sicuro

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

 43 

							
	WILMINGTON TRUST FSB, AS COLLATERAL AGENT,
			
		 	by	 	 /s/ Jane Schweiger

		 		 	Name:	 	Jane Schweiger
		 		 	Title:	 	Vice President

  

 44Lien Subordination and Intercreditor Agreement dated June 18, 2009

 Exhibit 4.18 
 EXECUTION COPY 
 LIEN SUBORDINATION AND INTERCREDITOR
AGREEMENT 
 LIEN SUBORDINATION AND INTERCREDITOR AGREEMENT (this “Agreement”) dated as of June 18,
2009, among US ONCOLOGY, INC. (the “Company”), a Delaware corporation, each Subsidiary of the Company listed on Schedule 1 hereto, JPMORGAN CHASE BANK, N.A. (“JPMCB”), as administrative agent and collateral agent
for the Senior Lenders (as defined below) (in such capacity, as further defined herein, the “Intercreditor Agent”), and WILMINGTON TRUST FSB, as collateral agent and trustee for the Secured Notes Holders (as defined below) (in such
capacity, as further defined herein, the “Notes Collateral Agent”). 
 A. The Company is party to the Credit
Agreement dated as of August 20, 2004 (as amended, restated, supplemented, waived or otherwise modified from time to time, the “Credit Agreement”), among US Oncology Holdings, Inc. (“Holdings”), the Company,
the Lenders party thereto from time to time, JPMCB, as Administrative Agent and Collateral Agent, Wachovia Bank National Association, as Syndication Agent, and Citicorp North America, Inc., as Documentation Agent. The credit facilities under the
Credit Agreement are included in the definition of “Credit Facilities” under the Secured Notes Indenture (as defined below), and the Obligations of the Company and certain of the Company’s Subsidiaries under the Credit Agreement and
the Senior Lender Documents executed or delivered pursuant thereto constitute First-Lien Indebtedness and First-Priority Lien Obligations hereunder. 
 B. The Company is party to the 9.125% Senior Secured Notes due 2017 Indenture dated as of June 18, 2009 (as amended, supplemented or otherwise modified from time to time, the “Secured Notes
Indenture”), among the Company, certain of the Company’s Subsidiaries and the Trustee (as defined herein). The Obligations of the Company, and certain of the Company’s Subsidiaries under the Secured Notes Indenture, the Notes, and
the other Noteholder Documents constitute Noteholder Claims and Second-Priority Obligations hereunder. 
 Accordingly, in
consideration of the foregoing, the mutual covenants and obligations herein set forth and for other good and valuable consideration, the sufficiency and receipt of which are hereby acknowledged, the parties hereto, intending to be legally bound,
hereby agree as follows: 
 ARTICLE I 
 Definitions 
 SECTION 1.01. Defined Terms. As used in this
Agreement, the following terms have the meanings specified below: 
 “Agreement” shall mean this Agreement, as
amended, renewed, extended, supplemented or otherwise modified from time to time in accordance with the terms hereof. 

 “Bankruptcy Law” shall mean Title 11 of the United States Code and any
similar Federal, state or foreign law for the relief of debtors. 
 “Business Day” shall mean any day other
than a Saturday, a Sunday or a day that is a legal holiday under the laws of the State of New York or on which banking institutions in the State of New York are required or authorized by law or other governmental action to close. 
 “Cash Management Obligations” shall mean, with respect to any Person, all obligations, whether now owing or hereafter
arising, of such Person in respect of overdrafts and related liabilities owed to any other Person that arise from treasury, depositary or cash management services, including any automated clearing house transfers of funds or any similar
transactions. 
 “Common Collateral” shall mean all of the assets of any Grantor, whether real, personal or
mixed, constituting both Senior Lender Collateral and Second-Priority Collateral. 
 “Company” shall have the
meaning set forth in the preamble. 
 “Comparable Second-Priority Collateral Document” shall mean, in relation
to any Common Collateral subject to any Lien created under any Senior Collateral Document, those Second-Priority Collateral Documents that create a Lien on the same Common Collateral, granted by the same Grantor. 
 “Credit Agreement” shall have the meaning set forth in the recitals and shall also include any other credit agreement, note
agreement, promissory note, indenture or other agreement or instrument evidencing or governing the terms of any indebtedness or other financial accommodation that has been incurred pursuant to Section 4.03(b)(2) of the Secured Notes Indenture
to extend, replace, refinance or refund in whole or in part the commitments, indebtedness and/or other obligations under the Credit Agreement (as set forth in the recitals) or any subsequent extension, replacement, refinancing or refunding thereof.
In the event the Company and/or any other Grantor shall enter into any extension, replacement, refinancing or refunding of any Credit Agreement at any time, written notice thereof by the Company to the Intercreditor Agent and the Notes Collateral
Agent shall constitute conclusive and binding evidence for all purposes of the existence of such extension, replacement, refinancing or refunding and thereafter the credit agreement, note agreement, promissory note, indenture or other agreement or
instrument referred to in such written notice shall constitute a “Credit Agreement” hereunder. 
 “Deposit
Account” shall have the meaning set forth in the Uniform Commercial Code. 
  

 2 

 “Deposit Account Collateral” shall mean that part of the Common Collateral
comprised of, or contained in, Deposit Accounts or Securities Accounts. 
 “DIP Financing” shall have the
meaning set forth in Section 6.01. 
 “Discharge of First-Priority Lien Obligations” shall mean, except to
the extent otherwise provided in Section 5.07, payment in full in cash (except for contingent indemnities and cost and reimbursement obligations to the extent no claim has been made) of (a) all Obligations in respect of all outstanding
First-Lien Indebtedness and, with respect to letters of credit or letter of credit guaranties outstanding thereunder, delivery of cash collateral or backstop letters of credit in respect thereof in compliance with the Senior Credit Agreement, in
each case after or concurrently with the termination of all commitments to extend credit thereunder and (b) any other First-Priority Lien Obligations that are due and payable or otherwise accrued and owing at or prior to the time such principal
and interest are paid. 
 “First-Lien Indebtedness” shall mean (a) any Indebtedness incurred under a
Credit Facility (under, and as defined in, the Secured Notes Indenture as in effect on the date hereof), including all Indebtedness incurred by the Company and its Subsidiaries pursuant to the Credit Agreement and the other Senior Lender Documents,
that is secured by a Permitted Lien (under, and as defined in, the Secured Notes Indenture as in effect on the date hereof and incurred or deemed incurred pursuant to clause (c) of the definition thereof), (b) all other Obligations (not
constituting Indebtedness) of the Company and its Subsidiaries under the Senior Lender Documents with respect to Indebtedness described in clause (a) and (c) all other Obligations of Holdings, the Company and its Subsidiaries in respect of
Hedging Obligations or Cash Management Obligations to the extent such Obligations are permitted to be secured pursuant to the terms of the Credit Agreement on an equal and ratable basis with Indebtedness described in clause (a). 
 “First-Priority Lien Obligations” shall mean (a) all First-Lien Indebtedness outstanding, including any Future
First-Lien Indebtedness, and (b) all other Obligations (not constituting Indebtedness under any such First-Lien Indebtedness) with respect to First-Lien Indebtedness, including all Senior Lender Hedging Obligations and Senior Lender Cash
Management Obligations. First-Priority Lien Obligations shall include all interest and expenses accrued or accruing (or that would, absent the commencement of an Insolvency or Liquidation Proceeding, accrue) after the commencement of an Insolvency
or Liquidation Proceeding in accordance with and at the rate specified in the relevant Senior Lender Document whether or not the claim for such interest or expenses is allowed or allowable as a claim in such Insolvency or Liquidation Proceeding.

 “Future First-Lien Indebtedness” shall mean any First-Lien Indebtedness other than First-Lien Indebtedness
referred to in clauses (a) and (b) of the definition of First-Lien Indebtedness incurred pursuant to the Credit Agreement (as set forth in the recitals) and the Senior Lender Documents entered into in connection therewith; provided,
however, that such First-Lien Indebtedness is permitted to be so incurred in accordance with the Second-Priority Documents and any Senior Lender Documents, as applicable. 
  

 3 

 “Future Second-Lien Indebtedness” shall mean Indebtedness or Obligations
(other than Noteholder Claims) of the Company and its Subsidiaries that is to be equally and ratably secured with the Noteholder Claims and is designated by the Company as Future Second-Lien Indebtedness hereunder and as Other Pari-Passu Lien
Obligations (under, and as defined in, the Secured Notes Indenture); provided, however, that such Future Second-Lien Indebtedness is permitted to be so incurred in accordance with any Senior Lender Documents and any Second-Priority
Documents, as applicable. 
 “Grantors” shall mean the Company and each of the Subsidiaries that has executed
and delivered a Second-Priority Collateral Document or a Senior Collateral Document. 
 “Hedging Obligations”
shall mean, with respect to any Person, all obligations and liabilities, whether now owing or hereafter arising, of such Person in respect of (a) currency exchange, interest rate or commodity swap agreements, currency exchange, interest rate or
commodity cap agreements, and currency exchange, interest rate or commodity collar agreements and (b) other agreements or arrangements designed to protect such Person against fluctuations in currency exchange, interest rates or commodity
prices. 
 “Indebtedness” shall mean and include all obligations that constitute “Debt” within the
meaning of the Secured Notes Indenture and “Indebtedness” within the meaning of the Senior Credit Agreement. 
 “Indenture Secured Parties” shall mean the Persons holding Noteholder Claims, including the Notes Collateral Agent and the Trustee. 
 “Insolvency or Liquidation Proceeding” shall mean (a) any voluntary or involuntary case or proceeding under any Bankruptcy Law with respect to any Grantor, (b) any other
voluntary or involuntary insolvency, reorganization or bankruptcy case or proceeding, or any receivership, liquidation, reorganization or other similar case or proceeding with respect to any Grantor or with respect to any of its assets, (c) any
liquidation, dissolution, reorganization or winding up of any Grantor whether voluntary or involuntary and whether or not involving insolvency or bankruptcy or (d) any assignment for the benefit of creditors or any other marshalling of assets
and liabilities of any Grantor. 
 “Intercreditor Agent” shall mean JPMCB, in its capacity as collateral agent
for the Senior Lenders under the Credit Agreement (as set forth in the recitals) and the other Senior Lender Documents entered into pursuant to the Credit Agreement (as set forth in the recitals), together with its successors (or if there is more
than one Senior Credit Agreement, such agent or trustee as is designated “Intercreditor Agent” by Senior Lenders holding a majority of the First-Priority Lien Obligations then outstanding) and permitted assigns under the Senior Credit
Agreement exercising substantially the same rights and powers. In the event that (a) the Company and/or any other Grantor shall enter into any extension, replacement, refinancing or refunding in full of any Credit Agreement or (b) there is
more than one Senior Credit Agreement, upon

  

 4 

 
execution and delivery by the Company and, in the case of clause (a), the collateral agent or collateral trustee under the new Credit Agreement or, in the case of clause (b), the agent or trustee
designated “Intercreditor Agent” by Senior Lenders holding a majority of the First-Priority Lien Obligations, an instrument in the form of Exhibit A hereto, such collateral agent or agent shall become the Intercreditor Agent hereunder with
the same force and effect as if originally the Intercreditor Agent under this Agreement and the existing Intercreditor Agent shall cease to be the Intercreditor Agent hereunder. The execution and delivery of any such instrument shall not require the
consent of any party hereunder (other than the Company and the incoming Intercreditor Agent). The rights and obligations of each party hereunder (other than the Intercreditor Agent being so replaced) shall remain in full force and effect
notwithstanding the replacement of the Intercreditor Agent as a party to this Agreement. 
 “JPMCB” shall have
the meaning set forth in the preamble. 
 “Lien” shall mean, with respect to any asset, any mortgage, deed of
trust, lien, pledge, hypothecation, assignment, deposit arrangement, easement, encumbrance, charge, preference, priority or other security interest in, on or of such asset. 
 “Noteholder Claims” shall mean all Obligations in respect of the Notes or arising under the Noteholder Documents or any of
them, including all fees and expenses of the Notes Collateral Agent and the Trustee thereunder. 
 “Noteholder
Collateral” shall mean all of the assets of any Grantor, whether real, personal or mixed, with respect to which a Lien is granted as security for any Noteholder Claim. 
 “Noteholder Collateral Agreement” shall mean the Collateral Agreement dated as of June 18, 2009, among the Company,
the Subsidiaries of the Company identified therein and the Notes Collateral Agent in respect of the Secured Notes Indenture. 
 “Noteholder Collateral Documents” shall mean the Noteholder Collateral Agreement and any other document or instrument pursuant to which a Lien is granted by any Grantor to secure any Noteholder Claims or under which rights
or remedies with respect to any such Lien are governed. 
 “Noteholder Documents” shall mean (a) the
Secured Notes Indenture, the Notes, and the Noteholder Collateral Documents and (b) any other related document or instrument executed and delivered pursuant to any Noteholder Document described in clause (a) above evidencing or governing
any Obligations thereunder. 
 “Notes” shall mean any notes issued under the Secured Notes Indenture.

 “Notes Collateral Agent” shall have the meaning set forth in the preamble. 
  

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 “Obligations” shall mean, with respect to any Indebtedness, any and all
obligations, whether now owing or hereafter arising, with respect to the payment of (a) any principal of or interest (including interest accrued on or accruing after the commencement of any Insolvency or Liquidation Proceeding, whether or not a
claim for post-filing interest is allowed in such proceeding) or premium on any Indebtedness, including any reimbursement obligation in respect of any letter of credit or letter of credit guaranty, (b) any fees, indemnification obligations,
expense reimbursement obligations or other liabilities payable under the documentation governing such Indebtedness and (c) any obligation to post cash collateral in respect of letters of credit or letter of credit guaranties and any other
obligations. 
 “Officers’ Certificate” shall have the meaning set forth in the Secured Notes Indenture.

 “Person” shall mean any natural person, corporation, limited liability company, trust, joint venture,
association, company, partnership, entity or other party, including any government and any political subdivision, agency or instrumentality thereof. 
 “Pledged Collateral” shall mean the Common Collateral in the possession of the Intercreditor Agent (or its agents or bailees), to the extent that possession thereof is necessary to
perfect a Lien thereon under the Uniform Commercial Code. 
 “Recovery” shall have the meaning set forth in
Section 6.04. 
 “Required Lenders” shall mean, with respect to any Senior Credit Agreement, those Senior
Lenders the approval of which is required to approve an amendment or modification of, termination or waiver of any provision of or consent to any departure from such Senior Credit Agreement (or would be required to effect such consent under this
Agreement if such consent were treated as an amendment of the Senior Credit Agreement). 
 “Second-Priority
Agents” shall mean (a) the Notes Collateral Agent as agent for the Indenture Secured Parties and (b) the collateral agent for any Future Second-Lien Indebtedness. 
 “Second-Priority Collateral” shall mean the Noteholder Collateral and all of the assets of any Grantor, whether real,
personal or mixed, with respect to which a Lien is granted as security for any Future Second-Lien Indebtedness. 
 “Second-Priority Collateral Agreements” shall mean the Noteholder Collateral Agreement and any comparable agreement with respect to any Future Second-Lien Indebtedness. 
 “Second-Priority Collateral Documents” shall mean the Noteholder Collateral Documents and any other agreement, document or
instrument pursuant to which a Lien is now or hereafter granted securing any Second-Priority Obligations or under which rights or remedies with respect to such Liens are at any time governed. 
  

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 “Second-Priority Designated Agent” shall mean such agent or trustee as is
designated “Second-Priority Designated Agent” by Second-Priority Secured Parties holding a majority in principal amount of the Second-Priority Obligations then outstanding; it being understood that as of the date of this agreement, the
Notes Collateral Agent shall be so designated Second-Priority Designated Agent. 
 “Second-Priority Documents”
shall mean the Noteholder Documents and any other document or instrument evidencing or governing any Future Second-Lien Indebtedness. 
 “Second-Priority Lien” shall mean any Lien on any assets of the Company or any other Grantor securing any Second-Priority Obligations. 
 “Second-Priority Obligations” shall mean the Noteholder Claims and all other Obligations in respect of, or arising under, the Second-Priority Documents, including all fees and expenses of
the collateral agent for any Future Second-Lien Indebtedness. Second-Priority Obligations shall include all interest and expenses accrued or accruing (or that would, absent the commencement of an Insolvency or Liquidation Proceeding, accrue) after
the commencement of an Insolvency or Liquidation Proceeding in accordance with and at the rate specified in the relevant Second-Priority Document whether or not the claim for such interest or expenses is allowed or allowable as a claim in such
Insolvency or Liquidation Proceeding. 
 “Second-Priority Secured Parties” shall mean the Indenture Secured
Parties and all other Persons holding any Second-Priority Obligations, including the collateral agent for any Future Second-Lien Indebtedness. 
 “Secured Notes Indenture” shall have the meaning set forth in the recitals. 
 “Securities Account” shall have the meaning set forth in the Uniform Commercial Code. 
 “Senior Collateral Documents” shall mean any agreement, document or instrument pursuant to which a Lien is now or hereafter granted securing any First-Priority Lien Obligations or under
which rights or remedies with respect to such Liens are at any time governed. 
 “Senior Credit Agreement”
shall mean the Credit Agreement and any other agreement governing any Future First-Lien Indebtedness. 
 “Senior Lender
Cash Management Obligations” shall mean any Cash Management Obligations that are permitted to be secured on an equal and ratable basis with the any Indebtedness under the Senior Credit Agreement by any Common Collateral under the Senior
Collateral Documents. 
 “Senior Lender Collateral” shall mean all of the assets of any Grantor, whether real,
personal or mixed, with respect to which a Lien is granted as security for any First-Priority Lien Obligation. 
  

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 “Senior Lender Documents” shall mean the Senior Credit Agreement, the
Senior Collateral Documents and each of the other agreements, documents and instruments (including each agreement, document or instrument providing for or evidencing a Senior Lender Hedging Obligation or Senior Lender Cash Management Obligation)
providing for, evidencing or securing any Obligation under the Credit Agreement or any Future First-Lien Indebtedness and any other related document or instrument executed or delivered pursuant to any Senior Lender Document at any time or otherwise
evidencing or securing any Indebtedness arising under any Senior Lender Document. 
 “Senior Lender Hedging
Obligations” shall mean any Hedging Obligations that are permitted to be secured on an equal and ratable basis with any Indebtedness under the Senior Credit Agreement by any Common Collateral under the Senior Collateral Documents.

 “Senior Lenders” shall mean the Persons holding First-Priority Lien Obligations, including the
Senior-Priority Agents. 
 “Senior-Priority Agents” shall mean (a) the collateral agent under the Credit
Agreement and (b) the collateral agent for any other First-Lien Indebtedness. 
 “Subsidiary” shall mean
any Person within the definition of “Subsidiary” under the Credit Agreement or the Secured Notes Indenture. 
 “Trustee” shall mean Wilmington Trust FSB, in its capacity as trustee under the Secured Notes Indenture and as collateral agent under the Noteholder Collateral Documents, and its permitted successors. 
 “Uniform Commercial Code” or “UCC” shall mean the Uniform Commercial Code as from time to time in effect
in the State of New York. 
 SECTION 1.02. Terms Generally. The definitions of terms herein shall apply equally to the
singular and plural forms of the terms defined. Whenever the context may require, any pronoun shall include the corresponding masculine, feminine and neuter forms. The words “include,” “includes” and “including” shall
be deemed to be followed by the phrase “without limitation”. The word “will” shall be construed to have the same meaning and effect as the word “shall”. Unless the context requires otherwise (a) any definition of
or reference to any agreement, instrument or other document herein shall be construed as referring to such agreement, instrument or other document as from time to time amended, supplemented or otherwise modified in accordance with this Agreement,
(b) any reference herein to any Person shall be construed to include such Person’s successors and assigns, (c) the words “herein,” “hereof” and “hereunder,” and words of similar import, shall be construed
to refer to this Agreement in its entirety and not to any particular provision hereof, (d) all references herein to Sections shall be construed to refer to Sections of this Agreement and (e) the words “asset” and
“property” shall be construed to have the same meaning and effect and to refer to any and all tangible and intangible assets and properties, including cash, securities, accounts and contract rights. 
  

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 ARTICLE II 
 Lien Priorities 
 SECTION 2.01. Subordination of Liens.
Notwithstanding the date, time, manner or order of filing or recordation of any document or instrument or grant, attachment or perfection of any Liens granted to the Second-Priority Secured Parties on the Common Collateral or of any Liens granted to
the Intercreditor Agent or the Senior Lenders on the Common Collateral and notwithstanding any provision of the UCC, or any applicable law or the Second-Priority Documents or the Senior Lender Documents or any other circumstance whatsoever, each
Second-Priority Agent, on behalf of itself and each applicable Second-Priority Secured Party, hereby agrees that: (a) any Lien on the Common Collateral securing any First-Priority Lien Obligations now or hereafter held by or on behalf of the
Intercreditor Agent or any Senior Lenders or any agent or trustee therefor regardless of how acquired, whether by grant, statute, operation of law, subrogation or otherwise, shall have priority over and be senior in all respects and prior to any
Lien on the Common Collateral securing any Second-Priority Obligations, (b) any Lien on the Common Collateral securing any Second-Priority Obligations now or hereafter held by or on behalf of the Trustee, the Notes Collateral Agent or any
Second-Priority Secured Parties or any agent or trustee therefor regardless of how acquired, whether by grant, statute, operation of law, subrogation or otherwise, shall be junior and subordinate in all respects to all Liens on the Common Collateral
securing any First-Priority Lien Obligations and (c) with respect to any Second-Priority Obligations (and as between the Second-Priority Agents and the Second-Priority Secured Parties), the Liens on the Common Collateral securing any
Second-Priority Obligations now or hereafter held by or on behalf of the Trustee, the Notes Collateral Agent or any Second-Priority Secured Party or any agent or trustee therefor regardless of how acquired, whether by grant, statute, operation of
law, subrogation or otherwise, shall rank equally and ratably in all respects. All Liens on the Common Collateral securing any First-Priority Lien Obligations shall be and remain senior in all respects and prior to all Liens on the Common Collateral
securing any Second-Priority Obligations for all purposes, whether or not such Liens securing any First-Priority Lien Obligations are subordinated to any Lien securing any other obligation of the Company, any other Grantor or any other Person.

 SECTION 2.02. Prohibition on Contesting Liens. Each Second-Priority Agent, for itself and on behalf of each applicable
Second-Priority Secured Party, and the Senior-Priority Agents, for itself and on behalf of each applicable Senior Lender, agrees that it shall not (and hereby waives any right to) contest or support any other Person in contesting, in any proceeding
(including any Insolvency or Liquidation Proceeding), the validity, perfection, priority or enforceability of (a) a Lien securing any First-Priority Lien Obligations held (or purported to be held) by or on behalf of the Intercreditor Agent, any
Senior-Priority Agent or any of the Senior Lenders or any agent or trustee therefor in

  

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any Senior Lender Collateral or (b) a Lien securing any Second-Priority Obligations held (or purported to be held) by or on behalf of any Second-Priority Secured Party in the Common
Collateral, as the case may be; provided, however, that nothing in this Agreement shall be construed to prevent or impair the rights of the Intercreditor Agent, any Senior-Priority Agent or any Senior Lender to enforce this Agreement
(including the priority of the Liens securing the First-Priority Lien Obligations as provided in Section 2.01) or any of the Senior Lender Documents. 
 SECTION 2.03. No New Liens. Subject to Section 5.01, so long as the Discharge of First-Priority Lien Obligations has not occurred, the parties hereto agree that, after the date hereof, if any
Second-Priority Agent shall hold any Lien on any assets of the Company or any other Grantor securing any Second-Priority Obligations that are not also subject to the first-priority Lien in respect of the First-Priority Lien Obligations under the
Senior Lender Documents, such Second-Priority Agent shall notify the Intercreditor Agent promptly upon becoming aware thereof and, upon demand by the Intercreditor Agent or the Company, will assign or release such Lien to the Intercreditor Agent
(and/or its designee) as security for the applicable First-Priority Lien Obligations (in the case of an assignment, each Second-Priority Agent may retain a junior lien on such assets subject to the terms hereof). Subject to Section 5.01, each
Second-Priority Agent agrees that, after the date hereof, if it shall hold any Lien on any assets of the Company or any other Grantor securing any Second-Priority Obligations that are not also subject to the Lien in favor of the other
Second-Priority Agent such Second-Priority Agent shall notify any other Second-Priority Agent promptly upon becoming aware thereof. To the extent that the foregoing provisions are not complied with for any reason, without limiting any other rights
or remedies available to the Intercreditor Agent or any of the Senior Lenders, the Second-Priority Agents and the Second-Priority Secured Parties agree that any amounts received by or distributed to any of them pursuant to or as a result of Liens
granted in contravention of this Section 2.03 shall be subject to Section 4.02. 
 SECTION 2.04. Perfection of
Liens. Neither the Intercreditor Agent nor the Senior Lenders shall be responsible for perfecting and maintaining the perfection of Liens with respect to the Common Collateral for the benefit of the Second-Priority Agents and the Second-Priority
Secured Parties. The provisions of this Intercreditor Agreement are intended solely to govern the respective Lien priorities as between the Senior Lenders and the Second-Priority Secured Parties and shall not impose on the Intercreditor Agent, the
Second-Priority Agents, the Second-Priority Secured Parties or the Senior Lenders or any agent or trustee therefor any obligations in respect of the disposition of proceeds of any Common Collateral which would conflict with prior perfected claims
therein in favor of any other Person or any order or decree of any court or governmental authority or any applicable law. 
 SECTION 2.05. No Duties of Intercreditor Agent. Each of the Second-Priority Secured Parties waives any claim such Second-Priority Secured Party may now or hereafter have against the Intercreditor Agent or any Senior Lender (or their
representatives) arising out of (i) any actions which the Intercreditor Agent or Senior Lenders take or omit to take with respect to the Common Collateral (including actions

  

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with respect to the creation, perfection or continuation of Liens on any Common Collateral, actions with respect to the foreclosure upon, sale, release or disposition of, or failure to realize
upon, any of the Common Collateral and actions with respect to the collection of any claim for all or any part of the First-Priority Lien Obligations from any account debtor, guarantor or any other party) or to the collection of the First-Priority
Lien Obligations or the valuation, use, protection or release of any security for the First-Priority Lien Obligations, (ii) any election by the Intercreditor Agent or any Senior Lender, in any proceeding instituted under the Bankruptcy Code, of
the application of Section 1111(b) of the Bankruptcy Code or (iii) any borrowing of, or grant of a security interest or administrative expense priority under Section 364 of the Bankruptcy Code to, or the use of cash collateral by, the
Company or any of its Subsidiaries, as debtor-in-possession. 
 ARTICLE III 
 Enforcement 
 SECTION 3.01. Exercise of Remedies. (a) So long as the Discharge of First-Priority Lien Obligations has not occurred, whether or not any Insolvency or Liquidation Proceeding has been commenced by or against the Company
or any other Grantor, (i) no Second-Priority Agent or any Second-Priority Secured Party will (x) exercise or seek to exercise any rights or remedies (including setoff) with respect to any Common Collateral in respect of any applicable
Second-Priority Obligations, institute any action or proceeding with respect to such rights or remedies (including any action of foreclosure), (y) contest, protest or object to any foreclosure proceeding or action brought with respect to the
Common Collateral by the Intercreditor Agent or any Senior Lender in respect of the First-Priority Lien Obligations, the exercise of any right by the Intercreditor Agent or any Senior Lender (or any agent or sub-agent on their behalf) in respect of
the First-Priority Lien Obligations under any lockbox agreement, control agreement, landlord waiver or bailee’s letter or similar agreement or arrangement to which any Second-Priority Agent or any Second-Priority Secured Party either is a party
or may have rights as a third party beneficiary, or any other exercise by any such party, of any rights and remedies relating to the Common Collateral under the Senior Lender Documents or otherwise in respect of First-Priority Lien Obligations, or
(z) object to the forbearance by the Senior Lenders from bringing or pursuing any foreclosure proceeding or action or any other exercise of any rights or remedies relating to the Common Collateral in respect of First-Priority Lien Obligations
and (ii) except as otherwise provided herein, the Intercreditor Agent and the Senior Lenders shall have the exclusive right to enforce rights, exercise remedies (including setoff and the right to credit bid their debt) and make determinations
regarding the release, disposition or restrictions with respect to the Common Collateral without any consultation with or the consent of any Second-Priority Agent or any Second-Priority Secured Party; provided, however, that
(A) in any Insolvency or Liquidation Proceeding commenced by or against the Company or any other Grantor, each Second-Priority Agent may file a claim or statement of interest with respect to the applicable Second-Priority Obligations and
(B) each Second-Priority Agent may take any action (not adverse to the prior Liens on the Common Collateral securing the First-Priority Lien Obligations, or the rights of the Intercreditor Agent or the Senior

  

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Lenders to exercise remedies in respect thereof) in order to create, prove, perfect, preserve or protect (but not enforce) its rights in, and perfection and priority of its Lien on, the Common
Collateral. In exercising rights and remedies with respect to the Senior Lender Collateral, the Intercreditor Agent and the Senior Lenders may enforce the provisions of the Senior Lender Documents and exercise remedies thereunder, all in such order
and in such manner as they may determine in the exercise of their sole discretion. Such exercise and enforcement shall include the rights of an agent appointed by them to sell or otherwise dispose of Common Collateral upon foreclosure, to incur
expenses in connection with such sale or disposition, and to exercise all the rights and remedies of a secured lender under the Uniform Commercial Code of any applicable jurisdiction and of a secured creditor under Bankruptcy Laws of any applicable
jurisdiction. 
 (b) So long as the Discharge of First-Priority Lien Obligations has not occurred, each Second-Priority Agent,
on behalf of itself and each applicable Second-Priority Secured Party, agrees that it will not, in the context of its role as secured creditor, take or receive any Common Collateral or any proceeds of Common Collateral in connection with the
exercise of any right or remedy (including setoff) with respect to any Common Collateral in respect of the applicable Second-Priority Obligations. Without limiting the generality of the foregoing, unless and until the Discharge of First-Priority
Lien Obligations has occurred, except as expressly provided in the proviso to clause (ii) of Section 3.01(a), the sole right of the Second-Priority Agents and the Second-Priority Secured Parties with respect to the Common Collateral is to
hold a Lien on the Common Collateral in respect of the applicable Second-Priority Obligations pursuant to the Second-Priority Documents, as applicable, for the period and to the extent granted therein and to receive a share of the proceeds thereof,
if any, after the Discharge of First-Priority Lien Obligations has occurred. 
 (c) Subject to the proviso to clause
(ii) of Section 3.01(a), (i) each Second-Priority Agent, for itself and on behalf of each applicable Second-Priority Secured Party, agrees that no Second-Priority Agent or any Second-Priority Secured Party will take any action that
would hinder any exercise of remedies undertaken by the Intercreditor Agent or the Senior Lenders with respect to the Common Collateral under the Senior Collateral Documents, including any sale, lease, exchange, transfer or other disposition of the
Common Collateral, whether by foreclosure or otherwise, and (ii) each Second-Priority Agent, for itself and on behalf of each applicable Second-Priority Secured Party, hereby waives any and all rights it or any Second-Priority Secured Party may
have as a junior lien creditor or otherwise to object to the manner in which the Intercreditor Agent or the Senior Lenders seek to enforce or collect the First-Priority Lien Obligations or the Liens granted in any of the Senior Lender Collateral,
regardless of whether any action or failure to act by or on behalf of the Intercreditor Agent or Senior Lenders is adverse to the interests of the Second-Priority Secured Parties. 
 (d) Each Second-Priority Agent hereby acknowledges and agrees that no covenant, agreement or restriction contained in any applicable
Second-Priority Document shall be deemed to restrict in any way the rights and remedies of the Intercreditor Agent or the Senior Lenders with respect to the Senior Lender Collateral as set forth in this Agreement and the Senior Lender Documents.

  

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 SECTION 3.02. Cooperation. Subject to the proviso in clause (ii) of
Section 3.01(a), each Second-Priority Agent, on behalf of itself and each applicable Second-Priority Secured Party, agrees that, unless and until the Discharge of First-Priority Lien Obligations has occurred, it will not commence, or join with
any Person (other than the Senior Lenders and the Intercreditor Agent upon the request thereof) in commencing, any enforcement, collection, execution, levy or foreclosure action or proceeding with respect to any Lien held by it in the Common
Collateral under any of the applicable Second-Priority Documents or otherwise in respect of the applicable Second-Priority Obligations. 
 ARTICLE IV 
 Payments 
 SECTION 4.01. Application of Proceeds. After an event of default under any First-Lien Indebtedness has occurred with respect to which the Intercreditor Agent has provided written notice to each
Second-Priority Agent, and until such event of default is cured or waived, so long as the Discharge of First-Priority Lien Obligations has not occurred, the Common Collateral or proceeds thereof received in connection with the sale or other
disposition of, or collection on, such Common Collateral upon the exercise of remedies, shall be applied by the Intercreditor Agent to the First-Priority Lien Obligations in such order as specified in the relevant Senior Lender Documents until the
Discharge of First-Priority Lien Obligations has occurred. Upon the Discharge of First-Priority Lien Obligations, the Intercreditor Agent shall deliver promptly to the Second-Priority Designated Agent any Common Collateral or proceeds thereof held
by it in the same form as received, with any necessary endorsements or as a court of competent jurisdiction may otherwise direct to be applied by the Second-Priority Designated Agent ratably to the Second-Priority Obligations and, with respect to
each class of Second-Priority Obligations, in such order as specified in the relevant Second-Priority Documents. 
 SECTION
4.02. Payments Over. So long as the Discharge of First-Priority Lien Obligations has not occurred, any Common Collateral or proceeds thereof received by any Second-Priority Agent or any Second-Priority Secured Party in connection with the
exercise of any right or remedy (including setoff) relating to the Common Collateral in contravention of this Agreement shall be segregated and held in trust for the benefit of and forthwith paid over to the Intercreditor Agent (and/or its
designees) for the benefit of the applicable Senior Lenders in the same form as received, with any necessary endorsements or as a court of competent jurisdiction may otherwise direct. Until the Discharge of First-Priority Lien Obligations, the
Intercreditor Agent is hereby authorized to make any such endorsements as agent for any Second-Priority Agent or any such Second-Priority Secured Party for purposes of this Section 4.02. This authorization is coupled with an interest and is
irrevocable. 
  

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 ARTICLE V 
 Other Agreements 
 SECTION 5.01. Releases. (a) If, at any time any
Grantor or the holder of any First-Priority Lien Obligation delivers written notice to each Second-Priority Agent that any specified Common Collateral (including all or substantially all of the equity interests of a Grantor or any of its
Subsidiaries that constitutes Common Collateral) is sold, transferred or otherwise disposed of: 
 (i) by the
owner of such Common Collateral in a transaction not prohibited under the Senior Lender Documents, the Secured Notes Indenture and each other Second-Priority Document (if any); 
 (ii) in connection with the foreclosure on or other exercise of remedies with respect to such Common Collateral by the
Intercreditor Agent; or 
 (iii) to the extent the Intercreditor Agent has consented to such sale, transfer or
disposition: 
 then (whether or not any Insolvency or Liquidation Proceeding is pending at the time) the Liens in favor of the Second-Priority
Secured Parties upon such Collateral will automatically be released and discharged as and when, but only to the extent, such Liens on such Collateral securing the First-Priority Lien Obligations are released and discharged (in the case of
Section 5.01(a)(iii), other than a release or discharge granted upon or following the Discharge of First-Priority Lien Obligations) unless (subject to Section 6.01(e)), in the case of a release or discharge under Section 5.01(a)(iii)
at the time of such release by the Senior Lenders, an Event of Default shall then have occurred and be continuing under the Second-Priority Documents (provided that any Liens in favor of the Second-Priority Secured Parties that would have
otherwise been released and terminated pursuant to Section 5.01(a)(iii) in the absence of such an Event of Default shall terminate and be released automatically without further action when such Event of Default (and all other Events of Default,
under the Second-Priority Documents) cease to exist), in each case except with respect to any proceeds of such Common Collateral that remain after the Discharge of First-Priority Lien Obligations. Upon delivery to each Second-Priority Agent of a
notice from the Intercreditor Agent stating that any release of Liens securing or supporting the First-Priority Lien Obligations has become effective (or shall become effective upon each Second-Priority Agent’s release), other than, in the case
of Section 5.03(a)(iii), such release granted upon or following the Discharge of First-Priority Lien Obligations, each Second-Priority Agent will promptly execute and deliver (at the sole cost and expense of the Grantors) such instruments,
releases, termination statements or other documents confirming such release on customary terms; provided that any Second-Priority Agent shall have the right to require an Officers’ Certificate or an Opinion of Counsel (as defined in the
Secured Notes Indenture), or both, in accordance with Section 11.03(a) of the Secured Notes Indenture or comparable provision in any other Second-Priority Document in connection with the execution and delivery of any such release or other
documents (including evidence of the concurrent release of the

  

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Liens securing the First-Priority Lien Obligations). In the case of the sale, transfer or other disposition of all or substantially all of the equity interests of a Grantor, the guarantee in
favor of the Second-Priority Secured Parties, if any, made by such Grantor will automatically be released and discharged as and when, but only to the extent, the guarantee by such Grantor of First-Priority Lien Obligations is released and discharged
(other than such release or discharge granted upon or following the Discharge of First-Priority Lien Obligations). 
 (b) Each
Second-Priority Agent, for itself and on behalf of each applicable Second-Priority Secured Party, hereby irrevocably constitutes and appoints the Intercreditor Agent and any officer or agent of the Intercreditor Agent, with full power of
substitution, as its true and lawful attorney-in-fact with full irrevocable power and authority in the place and stead of each Second-Priority Agent or such holder or in the Intercreditor Agent’s own name, from time to time in the Intercreditor
Agent’s discretion, for the purpose of carrying out the terms of this Section 5.01, to take any and all appropriate action and to execute any and all documents and instruments that may be necessary or desirable to accomplish the purposes
of this Section 5.01, including any termination statements, endorsements or other instruments of transfer or release. 
 (c) Unless and until the Discharge of First-Priority Lien Obligations has occurred, each Second-Priority Agent, for itself and on behalf of each applicable Second-Priority Secured Party, hereby consents to the application, whether prior to
or after a default, of Deposit Account Collateral or proceeds of Common Collateral to the repayment of First-Priority Lien Obligations pursuant to the Senior Credit Agreement; provided that nothing in this Section 5.01(c) shall be
construed to prevent or impair the rights of the Second-Priority Agents or the Second-Priority Secured Parties to receive proceeds in connection with the Second-Priority Obligations not otherwise in contravention of this Agreement. 
 SECTION 5.02. Insurance. Unless and until the Discharge of First-Priority Lien Obligations has occurred, the Intercreditor Agent and
the Senior Lenders shall have the sole and exclusive right, subject to the rights of the Grantors under the Senior Lender Documents, to adjust settlement for any insurance policy covering the Common Collateral in the event of any loss thereunder and
to approve any award granted in any condemnation or similar proceeding affecting the Common Collateral. Unless and until the Discharge of First-Priority Lien Obligations has occurred, all proceeds of any such policy and any such award if in respect
of the Common Collateral shall be paid (a) first, prior to the occurrence of the Discharge of First-Priority Lien Obligations, to the Intercreditor Agent for the benefit of Senior Lenders pursuant to the terms of the Senior Lender Documents,
(b) second, after the occurrence of the Discharge of First-Priority Lien Obligations, to the Second-Priority Agents for the benefit of the Second-Priority Secured Parties pursuant to the terms of the applicable Second-Priority Documents and
(c) third, if no Second-Priority Obligations are outstanding, to the owner of the subject property, such other person as may be entitled thereto or as a court of competent jurisdiction may otherwise direct. If any Second-Priority Agent or any
Second-Priority Secured Party shall, at any time, receive any proceeds of any such insurance policy or any such award in contravention of this Agreement, it shall pay such proceeds over to the Intercreditor Agent in accordance with the terms of
Section 4.02. 
  

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 SECTION 5.03. Amendments to Second-Priority Collateral Documents. (a) So long as the
Discharge of First-Priority Lien Obligations has not occurred, without the prior written consent of the Intercreditor Agent and the Required Lenders, no Second-Priority Collateral Document may be amended, supplemented or otherwise modified or
entered into to the extent such amendment, supplement or modification, or the terms of any new Second-Priority Collateral Document, would be prohibited by or inconsistent with any of the terms of this Agreement. Each Second-Priority Agent agrees
that each applicable Second-Priority Collateral Document shall include the following language (or language to similar effect approved by the Intercreditor Agent): 
 “Notwithstanding anything herein to the contrary, (i) the liens and security interests granted to the Collateral
Agent pursuant to this Agreement are expressly subject to and subordinate to the liens and security interests granted to (a) JPMorgan Chase Bank, N.A., as collateral agent (and its permitted successors and assigns) pursuant to the Guarantee and
Collateral Agreement dated as of August 20, 2004 (as amended, restated, supplemented or otherwise modified from time to time), by and among U.S. Oncology Holdings, Inc., the Company, the other “Grantors” named therein, JPMorgan Chase
Bank, N.A., as collateral agent and the other parties thereto (and any agreement entered into pursuant to a extension, replacement, refinancing or refunding of the First-Priority Lien Obligations secured thereby as permitted under the Secured Notes
Indenture) or (b) any agent or trustee for any other Senior Lenders (as defined in the Intercreditor Agreement), in the case of clause (a) and (b), to the extent provided in the Intercreditor Agreement and (ii) the exercise of any
right or remedy by the Collateral Agent and the other Secured Parties hereunder are subject to the limitations and provisions of the Intercreditor Agreement. In the event of any conflict or inconsistency between the Intercreditor Agreement and this
Agreement, the provisions of the Intercreditor Agreement shall control”. 
 (b) In the event that the Intercreditor Agent
or the Senior Lenders under the Credit Agreement or, if there is no Credit Agreement, any other Senior Lenders, enter into any amendment, waiver or consent in respect of or replace any of the Senior Collateral Documents for the purpose of adding to,
or deleting from, or waiving or consenting to any departures from any provisions of, any Senior Collateral Document or changing in any manner the rights of the Intercreditor Agent, the Senior Lenders, the Company or any other Grantor thereunder
(including the release of any Liens in Senior Lender Collateral), then such amendment, waiver or consent shall apply automatically to any comparable provision of each Comparable Second-Priority Collateral Document without the consent of any
Second-Priority Agent or any Second-Priority Secured Party and without any action by any Second-Priority Agent, Second-Priority Secured Party, the Company or any other Grantor; provided, however, that (A) such amendment, waiver or
consent does not materially adversely affect the rights of the Second-Priority Secured Parties or the interests of the Second-Priority Secured Parties in the Second-Priority Collateral and not the Intercreditor Agent or the Senior Lenders, as the
case may be, that

  

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have a security interest in the affected collateral in a like or similar manner and (B) written notice of such amendment, waiver or consent shall have been given to each Second-Priority
Agent promptly after the effectiveness of such amendment. 
 SECTION 5.04. Rights As Unsecured Creditors. To the extent
not inconsistent with the provisions of this Agreement, the Second-Priority Agents and the Second-Priority Secured Parties may exercise rights and remedies as unsecured creditors against the Company or any Subsidiary that has guaranteed the
Second-Priority Obligations in accordance with the terms of the applicable Second-Priority Documents and applicable law. Nothing in this Agreement shall prohibit the receipt by any Second-Priority Agent or any Second-Priority Secured Party of the
required payments of interest, principal, fees and other amounts so long as such receipt is not the direct or indirect result of the exercise by any Second-Priority Agent or any Second-Priority Secured Party of rights or remedies as a secured
creditor in respect of Common Collateral or enforcement in contravention of this Agreement of any Lien in respect of Second-Priority Obligations held by any of them. In the event any Second-Priority Agent or any Second-Priority Secured Party becomes
a judgment lien creditor in respect of Common Collateral as a result of its enforcement of its rights as an unsecured creditor in respect of Second-Priority Obligations, such judgment lien shall be subordinated to the Liens securing First-Priority
Lien Obligations on the same basis as the other Liens securing the Second-Priority Claims are so subordinated to such Liens securing First-Priority Lien Obligations under this Agreement. Nothing in this Agreement impairs or otherwise adversely
affects any rights or remedies the Intercreditor Agent or the Senior Lenders may have with respect to the Senior Lender Collateral. 
 SECTION 5.05. Intercreditor Agent as Gratuitous Bailee for Perfection. (a) The Intercreditor Agent agrees to hold the Pledged Collateral that is part of the Common Collateral in its possession or control (or in the possession or
control of its agents or bailees) as gratuitous bailee for each Second-Priority Agent and any assignee solely for the purpose of perfecting the security interest granted in such Pledged Collateral pursuant to the Second-Priority Collateral
Agreements, subject to the terms and conditions of this Section 5.05. 
 (b) The Intercreditor Agent agrees to hold the
Deposit Account Collateral that is part of the Common Collateral and controlled by the Intercreditor Agent as gratuitous bailee for each Second-Priority Agent and any assignee solely for the purpose of perfecting the security interest granted in
such Deposit Account Collateral pursuant to the Second-Priority Collateral Agreements, subject to the terms and conditions of this Section 5.05. 
 (c) In the event that the Intercreditor Agent (or its agent or bailees) has Lien filings against Intellectual Property that is part of the Common Collateral that are necessary for the perfection of Liens
in such Common Collateral, the Intercreditor Agent agrees to hold such Liens as gratuitous bailee for each Second-Priority Agent and any assignee solely for the purpose of perfecting the security interest granted in such Liens pursuant to the
Second-Priority Collateral Agreements, subject to the terms and conditions of this Section 5.05. 
  

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 (d) Except as otherwise specifically provided herein (including Sections 3.01 and
4.01), until the Discharge of First-Priority Lien Obligations has occurred, the Intercreditor Agent shall be entitled to deal with the Pledged Collateral in accordance with the terms of the Senior Lender Documents as if the Liens under the
Second-Priority Collateral Documents did not exist. The rights of the Second-Priority Agents and the Second-Priority Secured Parties with respect to such Pledged Collateral shall at all times be subject to the terms of this Agreement. 
 (e) The Intercreditor Agent shall have no obligation whatsoever to any Second-Priority Agent or any Second-Priority Secured Party to assure
that the Pledged Collateral is genuine or owned by the Grantors or to protect or preserve rights or benefits of any Person or any rights pertaining to the Common Collateral except as expressly set forth in this Section 5.05. The duties or
responsibilities of the Intercreditor Agent under this Section 5.05 shall be limited solely to holding the Pledged Collateral as gratuitous bailee for each Second-Priority Agent for purposes of perfecting the Lien held by the Second-Priority
Secured Parties. 
 (f) The Intercreditor Agent shall not have by reason of the Second-Priority Collateral Documents or this
Agreement or any other document a fiduciary relationship in respect of any Second-Priority Agent or any Second-Priority Secured Party and the Second-Priority Agents and the Second-Priority Secured Parties hereby waive and release the Intercreditor
Agent from all claims and liabilities arising pursuant to the Intercreditor Agent’s role under this Section 5.05, as agent and gratuitous bailee with respect to the Common Collateral. 
 (g) Upon the Discharge of First-Priority Lien Obligations, the Intercreditor Agent shall deliver to the Second-Priority Designated Agent, to
the extent that it is legally permitted to do so, the remaining Pledged Collateral (if any) and the Deposit Account Collateral (if any) together with any necessary endorsements (or otherwise allow the Second-Priority Designated Agent to obtain
control of such Pledged Collateral and Deposit Account Collateral) or as a court of competent jurisdiction may otherwise direct. The Company shall take such further action as is required to effectuate the transfer contemplated hereby and shall
indemnify the Intercreditor Agent for loss or damage suffered by the Intercreditor Agent as a result of such transfer except for loss or damage suffered by the Intercreditor Agent as a result of its own willful misconduct, gross negligence or bad
faith. The Intercreditor Agent has no obligation to follow instructions from any Second-Priority Agent in contravention of this Agreement. 
 (h) Neither the Intercreditor Agent nor the Senior Lenders shall be required to marshal any present or future collateral security for the Company’s or its Subsidiaries’ obligations to the
Intercreditor Agent or the Senior Lenders under the Senior Credit Agreement or the Senior Collateral Documents or any assurance of payment in respect thereof or to resort to such collateral security or other assurances of payment in any particular
order, and all of their rights in respect of such collateral security or any assurance of payment in respect thereof shall be cumulative and in addition to all other rights, however existing or arising. 
  

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 SECTION 5.06. Second-Priority Designated Agent as Gratuitous Bailee for Perfection.
(a) Upon the Discharge of First-Priority Lien Obligations, the Second-Priority Designated Agent agrees to hold the Pledged Collateral that is part of the Common Collateral in its possession or control (or in the possession or control of its agents
or bailees) as gratuitous bailee for the other Second-Priority Agents and any assignee solely for the purpose of perfecting the security interest granted in such Pledged Collateral pursuant to the applicable Second-Priority Collateral Agreement,
subject to the terms and conditions of this Section 5.06. 
 (b) Upon the Discharge of First-Priority Lien Obligations, the
Second-Priority Designated Agent agrees to hold the Deposit Account Collateral that is part of the Common Collateral and controlled by the Second-Priority Designated Agent as gratuitous bailee for the other Second-Priority Agents and any assignee
solely for the purpose of perfecting the security interest granted in such Deposit Account Collateral pursuant to the applicable Second-Priority Collateral Agreement, subject to the terms and conditions of this Section 5.06. 
 (c) In the event that the Second-Priority Designated Agent (or its agent or bailees) has Lien filings against Intellectual Property that is
part of the Common Collateral that are necessary for the perfection of Liens in such Common Collateral, upon the Discharge of First-Priority Lien Obligations, the Second-Priority Designated Agent agrees to hold such Liens as gratuitous bailee for
the other Second-Priority Agents and any assignee solely for the purpose of perfecting the security interest granted in such Liens pursuant to the applicable Second-Priority Collateral Agreement, subject to the terms and conditions of this
Section 5.06. 
 (d) The Second-Priority Designated Agent, in its capacity as gratuitous bailee, shall have no obligation
whatsoever to the other Second-Priority Agents to assure that the Pledged Collateral is genuine or owned by the Grantors or to protect or preserve rights or benefits of any Person or any rights pertaining to the Common Collateral except as expressly
set forth in this Section 5.06. The duties or responsibilities of the Second-Priority Designated Agent under this Section 5.06 upon the Discharge of First-Priority Lien Obligations shall be limited solely to holding the Pledged Collateral
as gratuitous bailee for the other Second-Priority Agents for purposes of perfecting the Lien held by the applicable Second-Priority Secured Parties. 
 (e) The Second-Priority Designated Agent shall not have by reason of the Second-Priority Collateral Documents or this Agreement or any other document a fiduciary relationship in respect of the other
Second-Priority Agents (or the Second-Priority Secured Parties for which such other Second-Priority Agents is agent) and the other Second-Priority Agents hereby waive and release the Second-Priority Designated Agent from all claims and liabilities
arising pursuant to the Second-Priority Designated Agent’s role under this Section 5.06, as agent and gratuitous bailee with respect to the Common Collateral. 
  

 19 

 (f) In the event that the Second-Priority Designated Agent shall cease to be so designated
the Second-Priority Designated Agent pursuant to the definition of such term, the then Second-Priority Designated Agent shall deliver to the successor Second-Priority Designated Agent, to the extent that it is legally permitted to do so, the
remaining Pledged Collateral (if any) and the Deposit Account Collateral (if any) together with any necessary endorsements (or otherwise allow the successor Second-Priority Designated Agent to obtain control of such Pledged Collateral and Deposit
Account Collateral) or as a court of competent jurisdiction may otherwise direct, and such successor Second-Priority Designated Agent shall perform all duties of the Second-Priority Designated Agent as set forth herein. The Company shall take such
further action as is required to effectuate the transfer contemplated hereto and shall indemnify the Second-Priority Designated Agent for loss or damage suffered by the Second-Priority Designated Agent as a result of such transfer except for loss or
damage suffered by the Second-Priority Designated Agent as a result of its own wilful misconduct, gross negligence or bad faith. The Second-Priority Designated Agent has no obligation to follow instructions from the successor Second-Priority
Designated Agent in contravention of this Agreement. 
 SECTION 5.07. When Discharge of First-Priority Lien Obligations
Deemed to Not Have Occurred. If, at any time after the Discharge of First-Priority Lien Obligations has occurred, the Company incurs and designates any Future First-Lien Indebtedness, then such Discharge of First-Priority Lien Obligations shall
automatically be deemed not to have occurred for all purposes of this Agreement (other than with respect to any actions taken prior to the date of such designation as a result of the occurrence of such first Discharge of First-Priority Lien
Obligations), and the applicable agreement governing such Future First-Lien Indebtedness shall automatically be treated as a Senior Credit Agreement for all purposes of this Agreement, including for purposes of the Lien priorities and rights in
respect of Common Collateral set forth herein and the granting by the Intercreditor Agent of amendments, waivers and consents hereunder. Upon receipt of notice of such designation (including the identity of the new Intercreditor Agent), each
Second-Priority Agent shall promptly (i) enter into such documents and agreements (at the expense of the Company), including amendments or supplements to this Agreement, as the Company or such new Intercreditor Agent shall reasonably request in
writing in order to provide the new Intercreditor Agent the rights of the Intercreditor Agent contemplated hereby and (ii) to the extent then held by any Second-Priority Agent, deliver to the Intercreditor Agent the Pledged Collateral that is
Common Collateral together with any necessary endorsements (or otherwise allow such Intercreditor Agent to obtain possession or control of such Pledged Collateral). 
 SECTION 5.08. Refinancings. The First-Priority Lien Obligations and the Second-Priority Obligations may be refinanced or replaced, in whole or in part, in each case, without notice to, or the
consent (except to the extent a consent is otherwise required to permit the refinancing transaction under any Senior Credit Agreement or any Second-Priority Document) of any Senior Lender or any Second-Priority Secured Party, all without affecting
the Lien priorities provided for herein or the other provisions hereof; provided, however, that the holders of any such refinancing or replacement indebtedness (or an authorized agent or trustee on their behalf) bind themselves in
writing to the terms of this Agreement pursuant to such documents or agreements (including amendments or supplements to this Agreement) as the Intercreditor Agent or the Second-Priority Designated Agent, as the case may be, shall reasonably request
and in form and substance

  

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reasonably acceptable to the Intercreditor Agent or the Second-Priority Designated Agent, as the case may be; provided that such documents or agreements shall comply with
Section 5.03(a). In connection with any refinancing or replacement contemplated by this Section 5.08, this Agreement may be amended at the request and sole expense of the Company, and without the consent of the Intercreditor Agent or any
Second-Priority Agent, (a) to add parties (or any authorized agent or trustee therefor) providing any such refinancing or replacement indebtedness and (b) to establish that Liens on any Common Collateral securing such refinancing or
replacement indebtedness shall have the same priority as the Liens on any Common Collateral securing the indebtedness being refinanced or replaced, all on the terms provided for herein immediately prior to such refinancing or replacement.

 SECTION 5.09. After Discharge of First-Priority Lien Obligations. Following the Discharge of First-Priority Lien
Obligations, the second-priority Liens on the Second-Priority Collateral will not be released, except to the extent such Second-Priority Collateral or any portion thereof was disposed of in order to repay the First-Lien Indebtedness secured by such
Second-Priority Collateral, and thereafter the Second-Priority Designated Agent will have the right to determine the time and method by which the security interests in the Second-Priority Collateral will be enforced. The Second-Priority Collateral
and the proceeds thereof received by the Second-Priority Designated Agent in connection with the sale or other disposition of, or collection on, such Second-Priority Collateral upon the exercise of remedies, shall be applied by the Second-Priority
Designated Agent in accordance with Section 4.01. 
 ARTICLE VI 
 Insolvency or Liquidation Proceedings 
 SECTION 6.01.
Financing Issues. If the Company or any other Grantor shall be subject to any Insolvency or Liquidation Proceeding and the Intercreditor Agent shall desire to permit the use of cash collateral or to permit the Company or any other Grantor to
obtain financing under Section 363 or Section 364 of Title 11 of the United States Code or any similar provision in any Bankruptcy Law (“DIP Financing”), then each Second-Priority Agent, on behalf of itself and each
applicable Second-Priority Secured Party, agrees that it will raise no (a) objection to (and will not otherwise contest) such use of cash collateral or DIP Financing and will not request adequate protection or any other relief in connection
therewith (except to the extent permitted by the proviso in clause (ii) of Section 3.01(a) and Section 6.03) and, to the extent the Liens securing the First-Priority Lien Obligations under the Credit Agreement or, if no Credit
Agreement exists, under the other Senior Lender Documents are subordinated or pari passu with such DIP Financing, will subordinate its Liens in the Common Collateral to such DIP Financing (and all Obligations relating thereto) on the
same basis as the other Liens securing the Second-Priority Obligations are so subordinated to Liens securing First-Priority Lien Obligations under this Agreement, (b) objection to (and will not otherwise contest) any motion for relief from the
automatic stay or from any injunction against foreclosure or enforcement in respect of First-Priority Lien Obligations made by the Intercreditor Agent or any holder of First-Priority Lien Obligations, (c) objection to (and

  

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will not otherwise contest) any lawful exercise by any holder of First-Priority Lien Obligations of the right to credit bid First-Priority Lien Obligations at any sale in foreclosure of Senior
Lender Collateral, (d) objection to (and will not otherwise contest) any other request for judicial relief made in any court by any holder of First-Priority Lien Obligations relating to the lawful enforcement of any Lien on Senior Lender
Collateral or (e) objection to (and will not otherwise contest) any order relating to a sale of assets of any Grantor for which the Intercreditor Agent has consented that provides, to the extent the sale is to be free and clear of Liens, that
the Liens securing the First-Priority Lien Obligations and the Second-Priority Obligations will attach to the proceeds of the sale on the same basis of priority as the Liens securing the First-Priority Lien Obligations rank to the Liens securing the
Second-Priority Obligations in accordance with this Agreement. 
 SECTION 6.02. Relief from the Automatic Stay. Until the
Discharge of First-Priority Lien Obligations has occurred, each Second-Priority Agent, on behalf of itself and each applicable Second-Priority Secured Party, agrees that none of them shall seek relief from the automatic stay or any other stay in any
Insolvency or Liquidation Proceeding in respect of the Common Collateral, without the prior written consent of the Intercreditor Agent and the Required Lenders. 
 SECTION 6.03. Adequate Protection. Each Second-Priority Agent, on behalf of itself and each applicable Second-Priority Secured Party, agrees that none of them shall contest (or support any other
Person contesting) (a) any request by the Intercreditor Agent or the Senior Lenders for adequate protection or (b) any objection by the Intercreditor Agent or the Senior Lenders to any motion, relief, action or proceeding based on the
Intercreditor Agent’s or the Senior Lenders’ claiming a lack of adequate protection. Notwithstanding the foregoing, in any Insolvency or Liquidation Proceeding, (i) if the Senior Lenders (or any subset thereof) are granted adequate
protection in the form of additional collateral in connection with any DIP Financing or use of cash collateral under Section 363 or Section 364 of Title 11 of the United States Code or any similar Bankruptcy Law, then each Second-Priority
Agent, on behalf of itself and any applicable Second-Priority Secured Party, may seek or request adequate protection in the form of a replacement Lien on such additional collateral, which Lien is subordinated to the Liens securing the First-Priority
Lien Obligations and such DIP Financing (and all Obligations relating thereto) on the same basis as the other Liens securing the Second-Priority Obligations are so subordinated to the Liens securing First-Priority Lien Obligations under this
Agreement and (ii) in the event any Second-Priority Agent, on behalf of itself or any applicable Second-Priority Secured Party, seeks or requests adequate protection and such adequate protection is granted in the form of additional collateral,
then such Second-Priority Agent, on behalf of itself or each such Second-Priority Secured Party, agrees that the Senior-Priority Agents shall also be granted a senior Lien on such additional collateral as security for the applicable First-Priority
Lien Obligations and any such DIP Financing and that any Lien on such additional collateral securing the Second-Priority Obligations shall be subordinated to the Liens on such collateral securing the First-Priority Lien Obligations and any such DIP
Financing (and all Obligations relating thereto) and any other Liens granted to the Senior Lenders as adequate protection on the same basis as the other Liens securing the Second-Priority Obligations are so subordinated to such Liens securing
First-Priority Lien Obligations under this Agreement. 
  

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 SECTION 6.04. Preference Issues. If any Senior Lender is required in any Insolvency
or Liquidation Proceeding or otherwise to turn over or otherwise pay to the estate of the Company or any other Grantor (or any trustee, receiver or similar person therefor), because the payment of such amount was declared to be fraudulent or
preferential in any respect or for any other reason, any amount (a “Recovery”), whether received as proceeds of security, enforcement of any right of setoff or otherwise, then the First-Priority Lien Obligations shall be reinstated
to the extent of such Recovery and deemed to be outstanding as if such payment had not occurred and the Senior Lenders shall be entitled to a Discharge of First-Priority Lien Obligations with respect to all such recovered amounts. If this Agreement
shall have been terminated prior to such Recovery, this Agreement shall be reinstated in full force and effect, and such prior termination shall not diminish, release, discharge, impair or otherwise affect the obligations of the parties hereto.

 SECTION 6.05. Application. This Agreement shall be applicable prior to and after the commencement of any Insolvency or
Liquidation Proceeding. All references herein to any Grantor shall apply to any trustee for such Person and such Person as debtor in possession. The relative rights as to the Collateral and proceeds thereof shall continue after the filing thereof on
the same basis as prior to the date of the petition, subject to any court order approving the financing of, or use of cash collateral by, any Grantor. 
 SECTION 6.06. 506(c) Claims. Until the Discharge of First-Priority Lien Obligations has occurred, each Second-Priority Agent, on behalf of itself and each applicable Second-Priority Secured Party,
will not assert or enforce any claim under Section 506(c) of the United States Bankruptcy Code senior to or on a parity with the Liens securing the First-Priority Lien Obligations for costs or expenses of preserving or disposing of any Common
Collateral. 
 SECTION 6.07. Post-Petition Interest. 
 (a) Neither the Second-Priority Agent nor any other Second-Priority Secured Party shall oppose or seek to challenge any claim by any
Senior-Priority Agent or any Senior Lender for allowance in any Insolvency or Liquidation Proceeding of First-Priority Lien Obligations consisting of post-petition interest, fees or expenses. Regardless of whether any such claim for post-petition
interest, fees or expenses is allowed or allowable, and without limiting the generality of the other provisions of this Agreement, this Agreement expressly is intended to include and does include the “rule of explicitness” in that this
Agreement expressly entitles the Senior Lenders, and is intended to provide the Senior Lenders with the right, to receive payment of all post-petition interest, fees or expenses through distributions made from Common Collateral or the proceeds
thereof pursuant to the provisions of this Agreement even though such interest, fees and expenses are not allowed or allowable against the bankruptcy estate of the Company or any other Grantor under Section 502(b)(2) or Section 506(b) of
the Bankruptcy Code or under any other provision of the Bankruptcy Code or any other Bankruptcy Law. 
  

 23 

 (b) Without limiting the foregoing, it is the intention of the parties hereto that (and to
the maximum extent permitted by law the parties hereto agree that) the First-Priority Lien Obligations (and the security therefor) in respect of the Common Collateral constitute a separate and distinct class (and separate and distinct claims) from
the Second-Priority Obligations (and the security therefor) in respect of the Common Collateral. 
 ARTICLE VII 
 Reliance; Waivers; Etc. 
 SECTION 7.01. Reliance. The consent by the Senior Lenders to the execution and delivery of the Second-Priority Documents to which the Senior Lenders have consented and all loans and other
extensions of credit made or deemed made on and after the date hereof by the Senior Lenders to the Company or any Subsidiary shall be deemed to have been given and made in reliance upon this Agreement. Each Second-Priority Agent, on behalf of itself
and each applicable Second-Priority Secured Party, acknowledges that it and the applicable Second-Priority Secured Parties have, independently and without reliance on the Intercreditor Agent or any Senior Lender, and based on documents and
information deemed by them appropriate, made their own credit analysis and decision to enter into the applicable Second-Priority Document, this Agreement and the transactions contemplated hereby and thereby and they will continue to make their own
credit decision in taking or not taking any action under the applicable Second-Priority Document or this Agreement. 
 SECTION
7.02. No Warranties or Liability. Each Second-Priority Agent, on behalf of itself and each applicable Second-Priority Secured Party, acknowledges and agrees that neither the Intercreditor Agent nor any Senior Lender has made any express or
implied representation or warranty, including with respect to the execution, validity, legality, completeness, collectibility or enforceability of any of the Senior Lender Documents, the ownership of any Common Collateral or the perfection or
priority of any Liens thereon. The Senior Lenders will be entitled to manage and supervise their respective loans and extensions of credit under the Senior Lender Documents in accordance with law and as they may otherwise, in their sole discretion,
deem appropriate, and the Senior Lenders may manage their loans and extensions of credit without regard to any rights or interests that any Second-Priority Agent or any of the Second-Priority Secured Parties have in the Common Collateral or
otherwise, except as otherwise provided in this Agreement. Neither the Intercreditor Agent nor any Senior Lender shall have any duty to any Second-Priority Agent or any Second-Priority Secured Party to act or refrain from acting in a manner that
allows, or results in, the occurrence or continuance of an event of default or default under any agreements with the Company or any Subsidiary thereof (including the Second-Priority Documents), regardless of any knowledge thereof that they may have
or be charged with. Except as expressly set forth in this Intercreditor Agreement, the Intercreditor Agent, the Senior Lenders, the Second-Priority

  

 24 

 
Agents and the Second-Priority Secured Parties have not otherwise made to each other, nor do they hereby make to each other, any warranties, express or implied, nor do they assume any liability
to each other with respect to (a) the enforceability, validity, value or collectibility of any of the Second-Priority Obligations, the First-Priority Lien Obligations or any guarantee or security which may have been granted to any of them in
connection therewith, (b) the Company’s or any other Grantor’s title to or right to transfer any of the Common Collateral or (c) any other matter except as expressly set forth in this Intercreditor Agreement. 
 SECTION 7.03. Obligations Unconditional. All rights, interests, agreements and obligations of the Intercreditor Agent and the Senior
Lenders, and the Second-Priority Agents and the Second-Priority Secured Parties, respectively, hereunder shall remain in full force and effect irrespective of: 
 (a) any lack of validity or enforceability of any Senior Lender Documents or any Second-Priority Documents; 
 (b) any change in the time, manner or place of payment of, or in any other terms of, all or any of the First-Priority Lien
Obligations or Second-Priority Obligations, or any amendment or waiver or other modification, including any increase in the amount thereof, whether by course of conduct or otherwise, of the terms of the Senior Credit Agreement or any other Senior
Lender Document or of the terms of the Secured Notes Indenture or any other Second-Priority Document; 
 (c) any
exchange of any security interest in any Common Collateral or any other collateral, or any amendment, waiver or other modification, whether in writing or by course of conduct or otherwise, of all or any of the First-Priority Lien Obligations or
Second-Priority Obligations or any guarantee thereof; 
 (d) the commencement of any Insolvency or Liquidation
Proceeding in respect of the Company or any other Grantor; or 
 (e) any other circumstances that otherwise might
constitute a defense available to, or a discharge of, the Company or any other Grantor in respect of the First-Priority Lien Obligations, or of any Second-Priority Agent or any Second-Priority Secured Party in respect of this Agreement. 

ARTICLE VIII 
 Miscellaneous 
 SECTION 8.01. Conflicts. Subject to Section 8.19, in the event of any conflict
between the provisions of this Agreement and the provisions of any Senior Lender Document or any Second-Priority Document, the provisions of this Agreement shall govern. 
  

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 SECTION 8.02. Continuing Nature of this Agreement; Severability. Subject to
Section 5.07 and Section 6.04, this Agreement shall continue to be effective until the Discharge of First-Priority Lien Obligations shall have occurred or such later time as all the Obligations in respect of the Second-Priority Obligations
shall have been paid in full. This is a continuing agreement of lien subordination and the Senior Lenders may continue, at any time and without notice to each Second-Priority Agent or any Second-Priority Secured Party, to extend credit and other
financial accommodations and lend monies to or for the benefit of the Company or any other Grantor constituting First-Priority Lien Obligations in reliance hereon. The terms of this Agreement shall survive, and shall continue in full force and
effect, in any Insolvency or Liquidation Proceeding. Any provision of this Agreement that is prohibited or unenforceable in any jurisdiction shall not invalidate the remaining provisions hereof, and any such prohibition or unenforceability in any
jurisdiction shall not invalidate or render unenforceable such provision in any other jurisdiction. 
 SECTION 8.03.
Amendments; Waivers. No amendment, modification or waiver of any of the provisions of this Agreement by any Second-Priority Agent or any Senior-Priority Agent shall be deemed to be made unless the same shall be in writing signed on behalf of
the party making the same or its authorized agent and each waiver, if any, shall be a waiver only with respect to the specific instance involved and shall in no way impair the rights of the parties making such waiver or the obligations of the other
parties to such party in any other respect or at any other time. The Company and the other Grantors shall not have any right to consent to or approve any amendment, modification or waiver of any provision of this Agreement except to the extent their
rights are affected. Notwithstanding anything in this Section 8.03 to the contrary, this Agreement may be amended from time to time at the request of the Company, at the Company’s expense, and without the consent of any Second-Priority
Agent, any Senior-Priority Agent, any Senior Lender or any Second-Priority Secured Party to (i) add other parties holding Future Second-Lien Indebtedness (or any agent or trustee therefor) and Future First-Lien Indebtedness (or any agent or
trustee therefor) in each case to the extent such Indebtedness is not prohibited by any Senior Credit Agreement, the Secured Notes Indenture or any other Second-Priority Document governing Future Second-Lien Indebtedness, (ii) in the case of
Future Second-Lien Indebtedness, (a) establish that the Lien on the Common Collateral securing such Future Second-Lien Indebtedness shall be junior and subordinate in all respects to all Liens on the Common Collateral securing any
First-Priority Lien Obligations and shall share in the benefits of the Common Collateral equally and ratably with all Liens on the Common Collateral securing any Second-Priority Obligations, and (b) provide to the holders of such Future
Second-Lien Indebtedness (or any agent or trustee thereof) the comparable rights and benefits (including any improved rights and benefits that have been consented to by the Intercreditor Agent) as are provided to the holders of Second-Priority
Obligations under this Agreement, and (iii) in the case of Future First-Lien Indebtedness, (a) establish that the Lien on the Common Collateral securing such Future First-Lien Indebtedness shall be superior in all respects to all Liens on
the Common Collateral securing any Second-Priority Obligations and any Future Second-Lien Indebtedness and shall share in the benefits of the Common Collateral equally and ratably with all Liens on the Common Collateral securing any First-Priority
Lien Obligations, and (b) provide to the holders of such Future First-Lien Indebtedness (or any agent or trustee thereof) the comparable rights and benefits as are provided to the holders of First-Priority Lien Obligations under

  

 26 

 
this Agreement, in each case so long as such modifications do not expressly violate the provisions of any Senior Credit Agreement, the Secured Notes Indenture or any other Second-Priority
Document governing Future Second-Lien Indebtedness. Any such additional party and each Second-Priority Agent shall be entitled to rely on the determination of officers of the Company that such modifications do not violate any Senior Credit
Agreement, the Secured Notes Indenture or any other Second-Priority Document governing Future Second-Lien Indebtedness if such determination is set forth in an Officers’ Certificate delivered to such party, the Intercreditor Agent and each
Second-Priority Agent; provided, however, that such determination will not affect whether or not the Company has complied with its undertakings in any Senior Credit Agreement, the Senior Collateral Documents, the Secured Notes
Indenture, any other Second-Priority Document governing Future Second-Lien Indebtedness, the Second-Priority Collateral Documents or this Agreement. Any amendment to this Agreement that is proposed to be effected without the consent of any
Senior-Priority Agent shall be submitted to such Senior-Priority Agent promptly after the effectiveness of such amendment, and no such Senior-Priority Agent shall be deemed to have knowledge of any such amendment until it receives a copy of such
amendment certified by the Company. Any amendment to this Agreement that is proposed to be effected without the consent of any Second-Priority Agent shall be submitted to such Second-Priority Agent promptly after the effectiveness of such amendment,
and no such Second-Priority Agent shall be deemed to have knowledge of any such amendment until it receives a copy of such amendment certified by the Company. 
 SECTION 8.04. Information Concerning Financial Condition of the Company and the Subsidiaries. None of the parties hereto (other than the Grantors) shall be responsible for keeping the other parties
hereto informed and no Second-Priority Agent shall be required to keep itself informed of (a) the financial condition of the Company and the Subsidiaries and all endorsers and/or guarantors of the Second-Priority Obligations or the
First-Priority Lien Obligations and (b) all other circumstances bearing upon the risk of nonpayment of the Second-Priority Obligations or the First-Priority Lien Obligations. The Intercreditor Agent, the Senior Lenders, each Second-Priority
Agent and the Second-Priority Secured Parties shall have no duty to advise any other party hereunder of information known to it or them regarding such condition or any such circumstances or otherwise. In the event that the Intercreditor Agent, any
Senior Lender, any Second-Priority Agent or any Second-Priority Secured Party, in its or their sole discretion, undertakes at any time or from time to time to provide any such information to any other party, it or they shall be under no obligation
(w) to make, and the Intercreditor Agent, the Senior Lenders, the Second-Priority Agents and the Second-Priority Secured Parties shall not make, any express or implied representation or warranty, including with respect to the accuracy,
completeness, truthfulness or validity of any such information so provided, (x) to provide any additional information or to provide any such information on any subsequent occasion, (y) to undertake any investigation or (z) to disclose
any information that, pursuant to accepted or reasonable commercial finance practices, such party wishes to maintain confidential or is otherwise required to maintain confidential. 
  

 27 

 SECTION 8.05. Subrogation. Each Second-Priority Agent, on behalf of itself and each
applicable Second-Priority Secured Party, hereby waives any rights of subrogation it may acquire as a result of any payment hereunder until the Discharge of First-Priority Lien Obligations has occurred; provided, however, that, as
between the Grantors, on the one hand, and the Second-Priority Secured Parties, on the other hand, any such payment that is paid over to the Intercreditor Agent shall be deemed not to reduce any of the Second-Priority Obligations unless and until
the Discharge of First-Priority Lien Obligations shall have occurred and the Intercreditor Agent delivers any such payment to the Second-Priority Designated Agent. 
 SECTION 8.06. Application of Payments. Except as otherwise provided herein, all payments received by the Senior Lenders may be applied, reversed and reapplied, in whole or in part, to such part of
the First-Priority Lien Obligations as the Senior Lenders, in their sole discretion, deem appropriate, consistent with the terms of the Senior Lender Documents. Except as otherwise provided herein, each Second-Priority Agent, on behalf of itself and
each applicable Second-Priority Secured Party, assents to any such extension or postponement of the time of payment of the First-Priority Lien Obligations or any part thereof and to any other indulgence with respect thereto, to any substitution,
exchange or release of any security that may at any time secure any part of the First-Priority Lien Obligations and to the addition or release of any other Person primarily or secondarily liable therefor. 
 SECTION 8.07. Consent to Jurisdiction; Waivers. The parties hereto consent to the jurisdiction of any state or federal court located
in New York, New York, and consent that all service of process may be made by registered mail directed to such party as provided in Section 8.08 for such party. Service so made shall be deemed to be completed three days after the same shall be
posted as aforesaid. The parties hereto waive any objection to any action instituted hereunder in any such court based on forum non conveniens, and any objection to the venue of any action instituted hereunder in any such court. Each of the parties
hereto waives any right it may have to trial by jury in respect of any litigation based on, or arising out of, under or in connection with this Agreement, or any course of conduct, course of dealing, verbal or written statement or action of any
party hereto in connection with the subject matter hereof. 
 SECTION 8.08. Notices. All notices to the Second-Priority
Secured Parties and the Senior Lenders permitted or required under this Agreement may be sent to the Notes Collateral Agent, the Intercreditor Agent or any Second-Priority Agent as provided in the Secured Notes Indenture, the Credit Agreement, the
other relevant Senior Lender Document or the relevant Second-Priority Document, as applicable. Unless otherwise specifically provided herein, any notice or other communication herein required or permitted to be given shall be in writing and may be
personally served, telecopied, electronically mailed or sent by courier service or U.S. mail and shall be deemed to have been given when delivered in person or by courier service, upon receipt of a telecopy or electronic mail or upon receipt via
U.S. mail (registered or certified, with postage prepaid and properly addressed). For the purposes hereof, the addresses of the parties hereto shall be as set forth below each party’s name on the signature pages hereto, or, as to each party, at
such other address as may be designated by such party in a written notice to all of the other parties. The Senior-Priority Agents hereby agree to promptly notify each Second-Priority Agent upon payment in full in cash of all Indebtedness under the
applicable Senior Lender Documents (except for contingent indemnities and cost and reimbursement obligations to the extent no claim therefor has been made). 
  

 28 

 SECTION 8.09. Further Assurances. Each of the Second-Priority Agents, on behalf of
itself and each applicable Second-Priority Secured Party, and the Intercreditor Agent, on behalf of itself and each Senior Lender, agrees that each of them shall take such further action and shall execute and deliver to the Intercreditor Agent and
the Senior Lenders such additional documents and instruments (in recordable form, if requested) as the Intercreditor Agent or the Senior Lenders may reasonably request to effectuate the terms of and the lien priorities contemplated by this
Agreement. 
 SECTION 8.10. Governing Law. This Agreement has been delivered and accepted at and shall be deemed to have
been made at New York, New York and shall be interpreted, and the rights and liabilities of the parties bound hereby determined, in accordance with the laws of the State of New York. 
 SECTION 8.11. Binding on Successors and Assigns. This Agreement shall be binding upon the Intercreditor Agent, the Senior Lenders,
the Second-Priority Agents, the Second-Priority Secured Parties, the Company, the Company’s Subsidiaries party hereto and their respective permitted successors and assigns. 
 SECTION 8.12. Specific Performance. The Intercreditor Agent and any Second-Priority Agent may demand specific performance of this
Agreement. Each Second-Priority Agent, on behalf of itself and each applicable Second-Priority Secured Party, and the Intercreditor Agent, on behalf of itself and each Senior Lender, hereby irrevocably waives any defense based on the adequacy of a
remedy at law and any other defense that might be asserted to bar the remedy of specific performance in any action that may be brought by the Intercreditor Agent or any Second-Priority Agent, as applicable. 
 SECTION 8.13. Section Titles. The section titles contained in this Agreement are and shall be without substantive meaning or
content of any kind whatsoever and are not a part of this Agreement. 
 SECTION 8.14. Counterparts. This Agreement may be
executed in one or more counterparts, including by means of facsimile, each of which shall be an original and all of which shall together constitute one and the same document. 
 SECTION 8.15. Authorization. By its signature, each Person executing this Agreement on behalf of a party hereto represents and
warrants to the other parties hereto that it is duly authorized to execute this Agreement. The Intercreditor Agent represents and warrants that this Agreement is binding upon the Senior Lenders. The Notes Collateral Agent represents and warrants
that this Agreement is binding upon the Indenture Secured Parties. 
 SECTION 8.16. No Third Party Beneficiaries; Successors
and Assigns. This Agreement and the rights and benefits hereof shall inure to the benefit of, and be binding upon, each of the parties hereto and their respective successors and assigns and 
 shall inure to the benefit of each of, and be binding upon, the holders of First-Priority Lien Obligations and Second-Priority Obligations. No other Person
shall have or be entitled to assert rights or benefits hereunder. 
  

 29 

 SECTION 8.17. Effectiveness. This Agreement shall become effective when executed and
delivered by the parties hereto. This Agreement shall be effective both before and after the commencement of any Insolvency or Liquidation Proceeding. All references to the Company or any other Grantor shall include the Company or any other Grantor
as debtor and debtor-in-possession and any receiver or trustee for the Company or any other Grantor (as the case may be) in any Insolvency or Liquidation Proceeding. 
 SECTION 8.18. Intercreditor Agent and Second-Priority Agents. It is understood and agreed that (a) JPMCB is entering into this Agreement in its capacity as administrative agent and collateral
agent under the Credit Agreement and the provisions of Article VIII of the Credit Agreement applicable to JPMCB as administrative agent thereunder shall also apply to JPMCB as Intercreditor Agent hereunder and (b) Wilmington Trust FSB is
entering into this Agreement in its capacity as Trustee and Notes Collateral Agent, and the provisions of Article 7 and Article 11 of the Secured Notes Indenture applicable to the Trustee and the Notes Collateral Agent thereunder shall also apply to
the Trustee and the Notes Collateral Agent hereunder. 
 SECTION 8.19. Relative Rights. Notwithstanding anything in this
Agreement to the contrary (except to the extent contemplated by Section 5.03 (b)), nothing in this Agreement is intended to or will (a) amend, waive or otherwise modify the provisions of the Senior Credit Agreement, the Secured Notes
Indenture or any other Senior Lender Documents or Second-Priority Documents entered into in connection with the Senior Credit Agreement, the Secured Notes Indenture or any other Senior Lender Document or Second-Priority Document or permit the
Company or any Subsidiary to take any action, or fail to take any action, to the extent such action or failure would otherwise constitute a breach of, or default under, the Senior Credit Agreement or any other Senior Lender Documents entered into in
connection with the Senior Credit Agreement, the Secured Notes Indenture or any other Second-Priority Documents, (b) change the relative priorities of the First-Priority Lien Obligations or the Liens granted under the Senior Lender Documents on
the Common Collateral (or any other assets) as among the Senior Lenders, (c) otherwise change the relative rights of the Senior Lenders in respect of the Common Collateral as among such Senior Lenders or (d) obligate the Company or any
Subsidiary to take any action, or fail to take any action, that would otherwise constitute a breach of, or default under, the Senior Credit Agreement or any other Senior Lender Document entered into in connection with the Senior Credit Agreement,
the Secured Notes Indenture or any other Second-Priority Documents. 
 SECTION 8.20. References. Notwithstanding anything
to the contrary in this Agreement, any references contained herein to any Section, clause, paragraph, definition or other provision of the Secured Notes Indenture (including any definition contained therein) shall be deemed to be a reference to such
Section, clause, paragraph, definition or other provision as in effect on the date of this Agreement; provided that any

  

 30 

 
reference to any such Section, clause, paragraph or other provision shall refer to such Section, clause, paragraph or other provision of the Secured Notes Indenture, as applicable (including any
definition contained therein), as amended or modified from time to time if such amendment or modification has been (1) made in accordance with the Secured Notes Indenture, and (2) approved in writing by, or on behalf of, the requisite
Senior Lenders as are needed under the terms of the Senior Credit Agreement to approve such amendment or modification. 
 SECTION 8.21. Intercreditor Agreements. Each party hereto agrees that the Senior Lenders (as among themselves) and the Second-Priority Secured Parties (as among themselves) may each enter into intercreditor agreements (or similar
arrangements) with the Intercreditor Agent governing the rights, benefits and privileges as among the Senior Lenders or the Second-Priority Secured Parties, as the case may be, in respect of the Common Collateral, this Agreement and the other Senior
Collateral Documents or Second-Priority Collateral Documents, as the case may be, including as to application of proceeds of the Common Collateral, voting rights, control of the Common Collateral and waivers with respect to the Common Collateral, in
each case so long as (A) the terms thereof do not violate or conflict with the provisions of this Agreement or the other Senior Collateral Documents or Second-Priority Collateral Documents, as the case may be, (B) in the case of any such
intercreditor agreement (or similar arrangement) affecting any Senior Lenders, the Senior-Priority Agent acting on behalf of such Senior Lenders agrees in its sole discretion to enter into any such intercreditor agreement (or similar arrangement)
and (C) in the case of any such intercreditor agreement (or similar arrangement) affecting the Senior Lenders holding First-Priority Lien Obligations under the Credit Agreement, the Required Lenders authorize the applicable Senior-Priority
Agent to enter into any such intercreditor agreement (or similar arrangement). Notwithstanding the preceding clauses (B) and (C), to the extent that the applicable Senior-Priority Agent is not authorized by the Required Lenders to enter into
any such intercreditor agreement (or similar arrangement ) or does not agree to enter into such intercreditor agreement (or similar arrangement ), such intercreditor agreement (or similar arrangement ) shall not be binding upon the applicable
Senior-Priority Agent but, subject to the immediately succeeding sentence, may still bind the other parties party thereto. In any event, if a respective intercreditor agreement (or similar arrangement) exists, the provisions thereof shall not be (or
be construed to be) an amendment, modification or other change to this Agreement or any other Senior Collateral Document or Second-Priority Collateral Document, and the provisions of this Agreement and the other Senior Collateral Documents and
Second-Priority Collateral Documents shall remain in full force and effect in accordance with the terms hereof and thereof (as such provisions may be amended, modified or otherwise supplemented from time to time in accordance with the terms thereof,
including to give effect to any intercreditor agreement (or similar arrangement)). 
 [Remainder of page intentionally left
blank] 
  

 31 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
written above. 
  

							
	INTERCREDITOR AGENT:
	
	JPMORGAN CHASE BANK, N.A., as Intercreditor Agent,
			
		 	by	 	

		 		 	Name:	 	Dawn L. LeeLum
		 		 	Title:	 	Executive Director

 [Signature Page to Intercreditor Agreement] 

							
	TRUSTEE AND NOTES COLLATERAL AGENT:
	
	WILMINGTON TRUST FSB, as Trustee and Notes Collateral Agent,
			
		 	by	 	

		 		 	Name:	 	Jane Schweiger
		 		 	Title:	 	Vice President

 [Signature Page to the Intercreditor Agreement] 

							
	US ONCOLOGY, INC.
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	 Chief Financial Officer and
   Executive Vice President

  

							
	ACCESSMED HOLDINGS, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	ACCESSMED, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	AOR HOLDING COMPANY OF INDIANA, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

 [Signature Page to Intercreditor Agreement] 

							
	AOR MANAGEMENT COMPANY OF ARIZONA, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	AOR MANAGEMENT COMPANY OF INDIANA, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	AOR MANAGEMENT COMPANY OF MISSOURI, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	AOR MANAGEMENT COMPANY OF OKLAHOMA, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

 [Signature Page to Intercreditor Agreement] 

							
	AOR MANAGEMENT COMPANY OF PENNSYLVANIA, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	AOR MANAGEMENT COMPANY OF VIRGINIA, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  
  

							
	AOR OF INDIANA MANAGEMENT PARTNERSHIP, AS A SUBSIDIARY GUARANTOR,
		
		 	By: AOR Management Company of Indiana, LLC, its general partner
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
		 	and
		
		 	By: AOR Holding Company of Indiana, LLC, its general partner
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

 [Signature Page to Intercreditor Agreement] 

							
	AOR OF TEXAS MANAGEMENT, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	AOR REAL ESTATE, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	AOR SYNTHETIC REAL ESTATE, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	AORT HOLDING COMPANY, INC., AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	GREENVILLE RADIATION CARE, INC., AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

 [Signature Page to Intercreditor Agreement] 

							
	INNOVENT ONCOLOGY, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	IOWA PHARMACEUTICAL SERVICES, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	NEBRASKA PHARMACEUTICAL SERVICES, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	NEW MEXICO PHARMACEUTICAL SERVICES, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	NORTH CAROLINA PHARMACEUTICAL SERVICES, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

 [Signature Page to Intercreditor Agreement] 

							
	ONCOLOGY RX CARE ADVANTAGE, LP, AS A SUBSIDIARY GUARANTOR,
		
		 	By: US Oncology Corporate, Inc., its general partner
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	ONCOLOGY TODAY, LP, AS A SUBSIDIARY GUARANTOR,
		
		 	By: US Oncology Corporate, Inc., its general partner
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	PHYSICIAN RELIANCE, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	PHYSICIAN RELIANCE NETWORK, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

 [Signature Page to Intercreditor Agreement] 

							
	RMCC CANCER CENTER, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	SELECTPLUS ONCOLOGY, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	ST. LOUIS PHARMACEUTICAL SERVICES, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	TEXAS PHARMACEUTICAL SERVICES, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	UNITY ONCOLOGY, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

 [Signature Page to Intercreditor Agreement] 

							
	TOPS PHARMACY SERVICES, INC., AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	US ONCOLOGY CLINICAL DEVELOPMENT, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	US ONCOLOGY CORPORATE, INC., AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	US ONCOLOGY INTEGRATED SOLUTIONS, LP, AS A SUBSIDIARY GUARANTOR,
		
		 	By: US Oncology Corporate, Inc., its general partner
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

 [Signature Page to Intercreditor Agreement] 

							
	US ONCOLOGY PHARMACEUTICAL SERVICES, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	US ONCOLOGY REIMBURSEMENT SOLUTIONS, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	US ONCOLOGY RESEARCH, LLC, AS A SUBSIDIARY GUARANTOR,
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

  

							
	US ONCOLOGY SPECIALTY, LP, AS A SUBSIDIARY GUARANTOR,
		
		 	By: US Oncology Corporate, Inc., its general partner
			
		 	By:	 	

		 		 	Name:	 	Michael A. Sicuro
		 		 	Title:	 	Vice President and Treasurer

 [Signature Page to Intercreditor Agreement] 

 SCHEDULE I 
 Subsidiary Parties 
 AccessMED Holdings, LLC 
 AccessMED, LLC 
 AOR Holding Company of Indiana, LLC

 AOR Management Company of Arizona, LLC 
 AOR Management Company of Indiana, LLC 
 AOR Management Company of Missouri, LLC 
 AOR Management Company of Oklahoma, LLC 
 AOR
Management Company of Pennsylvania, LLC 
 AOR Management Company of Virginia, LLC 
 AOR of Indiana Management Partnership 
 AOR of Texas Management, LLC 
 AOR Real Estate, LLC 
 AOR Synthetic Real Estate,
LLC 
 AORT Holding Company, Inc. 
 Greenville Radiation Care, Inc. 
 Innovent Oncology, LLC 
 Iowa Pharmaceutical Services, LLC 
 Nebraska Pharmaceutical Services, LLC 
 New Mexico Pharmaceutical Services, LLC 
 North
Carolina Pharmaceutical Services, LLC 
 Oncology Rx Care Advantage, LP 
 Oncology Today, LP 
 Physician Reliance, LLC 
 Physician Reliance Network, LLC 
 RMCC Cancer
Center, LLC 
 SelectPlus Oncology, LLC 
 St. Louis Pharmaceutical Services, LLC 
 Texas Pharmaceutical Services, LLC 
 Unity Oncology, LLC 
 TOPS Pharmacy Services, Inc.

 US Oncology Clinical Development, LLC 
 US Oncology Corporate, Inc. 
 US Oncology Integrated Solutions, LP 
 US Oncology Pharmaceutical Services, LLC 
 US Oncology Reimbursement Solutions, LLC 
 US Oncology Research, LLC 
 US Oncology Specialty,
LP 

 EXHIBIT A 
 JOINDER AGREEMENT 
 THIS JOINDER AGREEMENT (this
“Agreement”), dated as of [—], is by and between [—] (the “Successor Agent”) and US ONCOLOGY, INC. (the
“Company”). Capitalized terms used herein but not otherwise defined shall have the meanings provided in the Intercreditor Agreement, dated as of June 18, 2009, among the Company, the Subsidiary Guarantors party thereto, the
Exiting Agent (as defined below) and the Successor Agent (as amended, restated, supplemented waived or otherwise modified from time to time, the “Intercreditor Agreement”). 
 The Successor Agent is succeeding [—] (the “Exiting Agent”), as
[administrative agent and collateral agent for the Senior Lenders], and, consequently, the Successor Agent desires to become a party to the Intercreditor Agreement. 
 Accordingly, the Successor Agent and the Company agree as follows: 
 1. The
Successor Agent hereby (i) acknowledges, agrees and confirms that, by its execution of this Agreement, the Successor Agent will be deemed to be a party to the Intercreditor Agreement, and shall have all of the obligations of the Exiting Agent
under the Intercreditor Agreement as if it had executed the Intercreditor Agreement, and (ii) ratifies, as of the date hereof, and agrees to be bound by, all of the terms, provisions and conditions contained in the Intercreditor Agreement.

 2. The Successor Agent acknowledges and confirms that it has received a copy of the Intercreditor Agreement and the schedules
and exhibits thereto. 
 3. Except as specifically provided herein, all of the terms and conditions of the Intercreditor
Agreement shall remain in full force and effect as in effect prior to the date hereof. 
 4. This Agreement may be executed in
any number of counterparts and by different parties in separate counterparts, each of which when so executed shall be deemed to be an original and all of which when taken together shall constitute one and the same agreement. Signature pages may be
detached from multiple separate counterparts and attached to a single counterpart. Delivery of an executed signature page of this Agreement by facsimile transmission or electronic transmission shall be as effective as delivery of a manually executed
counterpart hereof. 
 5. The laws of the State of New York shall govern all matters arising out of, in connection with or
relating to this Agreement, including, without limitation, its validity, interpretation, construction, performance and enforcement. 
 [SIGNATURES ON FOLLOWING PAGES] 

 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be duly executed and
delivered by their duly authorized officers as of the day and year first above written. 
  

			
	SUCCESSOR AGENT:
		
	By:	 	 
	Name: 	 	 
	Its:	 	 

  

			
	COMPANY:
		
	By:	 	 
	Name: 	 	 
	Its:	 	 

 [Intercreditor Joinder Agreement]

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00164-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00164-of-00352.parquet"}]]