Document:

2003 Long Term Incentive Plan of C.R. Bard, Inc.

 Exhibit 10bs 
 2003 LONG TERM INCENTIVE PLAN 
 OF 
 C. R. BARD, INC. 
 (AS AMENDED AND RESTATED) 
 Effective as of April 16, 2008, the 2003 Long Term Incentive Plan of C. R. Bard, Inc. (the “Plan”) is hereby amended and restated by C. R.
Bard, Inc., a New Jersey corporation (the “Corporation”), as set forth herein. The Plan was originally effective as of April 16, 2003. 
 SECTION 1. — Purpose of the Plan 
 The 2003 Long Term Incentive Plan of C. R. Bard, Inc. is designed to attract and
retain the services of selected employees of the Corporation and its Subsidiaries and to motivate such employees to exert their best efforts on behalf of the Corporation and its Subsidiaries by providing incentives through the granting of Awards.
The Corporation expects that it will benefit from the added interest that such employees will have in the welfare of the Corporation as a result of their proprietary interest in the Corporation’s success. The Plan may be used to grant
equity-based awards under various compensation programs of the Corporation, as determined in the discretion of the Compensation Committee of the Board of Directors of the Corporation and in accordance with the terms hereof. The Committee shall have
the full authority to establish the terms and conditions of any Award granted under the Plan, subject to the terms and limitations contained herein. 
 SECTION 2. — Definitions 
 The following capitalized terms used in the Plan have the respective meanings set forth in
this Section: 
 (a) Act: The Securities Exchange Act of 1934, as amended (or any successor statute thereto). 
 (b) Award: An Option, Stock Appreciation Right or Other Stock-Based Award granted pursuant to the Plan. 
 (c) Board: The Board of Directors of the Corporation. 
 (d) Change of Control: A change of control of the nature that would be required to be reported in response to Item 1(a) of the Current Report on Form 8-K as in effect on April 16, 2003, pursuant to
Section 13 or 15(d) of the Act (other than such a change of control involving a Permitted Holder); provided, that, without limitation, a Change of Control shall be deemed to have occurred if: 
 (i) any “person” (other than a Permitted Holder) shall become the “beneficial owner”, as those terms are defined
below, of capital stock of the Corporation, the voting power of which constitutes 20% or more of the general voting power of all of the Corporation’s outstanding capital stock; or 
 (ii) individuals who, as of April 16, 2003, constituted the Board (the “Incumbent Board”) cease for any reasons to
constitute at least a majority of the Board; provided, that any person becoming a Director subsequent to April 16, 2003, whose election, or nomination for election by the Corporation’s shareholders, was approved by a vote of at
least three quarters of the Directors comprising the Incumbent Board (other than an election or nomination of an individual whose initial assumption of office is in connection with an actual or threatened election contest relating to the election of
the Directors of the Corporation, which is or would be subject to Rule 14a-11 of the Regulation 14A promulgated under the Act) shall be, for purposes of the Plan, considered as though such person were a member of the Incumbent Board. 
 For purposes of the definition of Change of Control, the following definitions shall be applicable: 
 (1) The term “person” shall mean any individual, group, corporation or other entity. 
 (2) For purposes of this definition only, any person shall be deemed to be the “beneficial owner” of any shares of capital
stock of the Corporation: 
 (i) which that person owns directly, whether or not of record, or 
 (ii) which that person has the right to acquire pursuant to any agreement or understanding or upon exercise of conversion rights,
warrants, or options, or otherwise, or 
 (iii) which are beneficially owned, directly or indirectly (including shares
deemed owned through application of clause (ii) above), by an “affiliate” or “associate” (as defined in the rules of the Securities and Exchange Commission under the Securities Act of 1933, as amended) of that person, or

 (iv) which are beneficially owned, directly or indirectly (including shares deemed owned through application of
clause (ii) above), by any other person with which that person or such 

  

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person’s “affiliate” or “associate” (defined as aforesaid) has any agreement, arrangement or understanding for the purpose of
acquiring, holding, voting or disposing of capital stock of the Corporation. 
 (3) The outstanding shares of capital
stock of the Corporation shall include shares deemed owned through application of clauses (2)(ii), (iii) and (iv), above, but shall not include any other shares which may be issuable pursuant to any agreement or upon exercise of conversion
rights, warrants or options, or otherwise, but which are not actually outstanding. 
 (e) Code: The Internal Revenue Code of 1986, as
amended (or any successor statute thereto). 
 (f) Committee: The Compensation Committee of the Board, or such other committee as may
be designated by the Board. 
 (g) Corporation: C. R. Bard, Inc., a New Jersey corporation. 
 (h) Director: A member of the Board. 
 (i) Disability: Inability of a Participant to perform in all material respects his duties and responsibilities to the Corporation, or any Subsidiary of the Corporation, by reason of a physical or mental disability or infirmity which
inability is reasonably expected to be permanent and has continued (i) for a period of six consecutive months or (ii) such shorter period as the Committee may reasonably determine in good faith. The Disability determination shall be in the
sole discretion of the Committee. 
 (j) Effective Date: April 16, 2008, provided that the Plan, as amended and restated, shall
have been approved by the shareholders of the Corporation. 
 (k) Fair Market Value: On a given date, (i) if there should be a
public market for the Shares on such date, the arithmetic mean of the high and low prices of the Shares as reported on such date on the Composite Tape of the principal national securities exchange on which such Shares are listed or admitted to
trading, or, if the Shares are not listed or admitted on any national securities exchange, the arithmetic mean of the per Share closing bid price and per Share closing asked price on such date as quoted on the National Association of Securities
Dealers Automated Quotation System (or such market in which such prices are regularly quoted) (the “NASDAQ”), or, if no sale of Shares shall have been reported on the Composite Tape of any national securities exchange or quoted on the
NASDAQ on such date, then the immediately preceding date on which sales of the Shares have been so reported or quoted shall be used, and (ii) if there should not be a public market for the Shares on such date, the Fair Market Value shall be the
value established by the Committee in good faith. 
 (l) ISO: An Option that is also an incentive stock option granted pursuant to
Section 6(d) of the Plan. 
 (m) LSAR: A limited stock appreciation right granted pursuant to Section 7(d) of the Plan.

 (n) Other Stock-Based Awards: Awards granted pursuant to Section 8 of the Plan. 
 (o) Option: A stock option granted pursuant to Section 6 of the Plan. 
 (p) Option Price: The purchase price per Share of an Option, as determined pursuant to Section 6(a) of the Plan. 
 (q) Participant: An employee of the Corporation or any of its Subsidiaries who is selected by the Committee to participate in the Plan. 

(r) Permitted Exceptions: The Board may amend the Plan at any time to terminate restrictions applicable to Awards in connection with (i) a
Change of Control, (ii) a Participant’s death, Disability, retirement, or Qualified Termination, or (iii) any termination of employment other than a Qualified Termination; provided, however, that the amount of Awards with
respect to which the Board terminates restrictions pursuant to this subsection (iii) together with any Awards granted pursuant to Section 8(a)(ii) hereof does not in the aggregate exceed 5% of the total number of Shares that may be issued
under the Plan from time to time. 
 (s) Permitted Holder means, as of the date of determination: (i) an employee benefit plan (or
trust forming a part thereof) maintained by the Corporation or any corporation or other person of which a majority of its voting power of its voting equity securities or equity interest is owned, directly or indirectly, by the Corporation (a
“Controlled Entity”); (ii) the Corporation or any Controlled Entity; (iii) any entity, which directly or indirectly through a majority-owned Subsidiary, following a transaction described in paragraph (d) above, owns the
stock or assets of the Corporation, and in which a majority of the combined voting power of the voting securities of such entity is held by the shareholders of the Corporation who were shareholders of the Corporation immediately prior to such
transaction, in substantially the same proportion to each other that they were prior to the transaction; or (iv) an underwriter in a public offering, or purchaser in a private placement, of capital stock by the Corporation. 
  

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 (t) Performance-Based Awards: Certain Other Stock-Based Awards granted pursuant to
Section 8(b) of the Plan. 
 (u) Plan: The 2003 Long Term Incentive Plan of C. R. Bard, Inc., as amended from time to time.

 (v) Qualified Termination: Termination of employment in connection with the divestiture, sale or other disposition of a business or
assets of the Corporation. 
 (w) Shares: Shares of common stock of the Corporation. 
 (x) Stock Appreciation Right: A stock appreciation right granted pursuant to Section 7 of the Plan. 
 (y) Subsidiary: A subsidiary corporation, as defined in Section 424(f) of the Code (or any successor section thereto). 
 SECTION 3. — Shares Subject to the Plan 
 Subject
to adjustment as provided in Section 9, (i) the total number of Shares which may be issued under the Plan is 14,725,000 and (ii) the maximum number of Shares for which Options and Stock Appreciation Rights or Other Stock-Based Awards
under Section 8(b) may be granted during a calendar year to any Participant shall not exceed 900,000. The maximum number of Shares that may be granted as Awards of restricted Shares, unrestricted Shares, restricted Share units, or Other
Stock-Based Awards shall not exceed 3,475,000 shares in the aggregate. The Shares may consist, in whole or in part, of unissued Shares or treasury Shares. The issuance of Shares or the payment of cash upon the exercise of an Award or in
consideration of the cancellation or termination of an Award shall reduce the total number of Shares available under the Plan, as applicable. Shares subject to Awards which are forfeited, terminate or otherwise lapse will be added back to the
aggregate number of Shares available under the Plan. Notwithstanding the foregoing, the following Shares shall not become available for issuance under the Plan: (i) Shares tendered by Participants as full or partial payment to the Corporation
upon the exercise of Options granted under the Plan; (ii) Shares reserved for issuance upon the grant of Stock Appreciation Rights, to the extent the number of reserved Shares exceeds the number of Shares actually issued upon the exercise of
the Stock Appreciation Rights; and (iii) Shares withheld by, or otherwise remitted to, the Corporation to satisfy a Participant’s tax withholding obligations upon the lapse of restrictions on restricted Shares or the exercise of Options or
Stock Appreciation Rights granted under the Plan. 
 SECTION 4. — Administration 
 The Plan shall be administered by the Committee, which may delegate its duties and powers in whole or in part to any subcommittee thereof; it is expected
that such subcommittee shall consist solely of at least two individuals who are intended to qualify as “Non-Employee Directors” within the meaning of Rule 16b-3 under the Act (or any successor rule thereto) and “outside
directors” within the meaning of Section 162(m) of the Code (or any successor section thereto); provided, however, that the failure of the subcommittee to be so constituted shall not impair the validity of any Award made by such
subcommittee. Subject to the provisions of the Plan, the Committee shall have exclusive power to select the Participants and to determine the amount of, or method of determining, the Awards to be made to Participants. All Awards granted to
Participants under the Plan shall be evidenced by an Award agreement which specifies the type of Award granted pursuant to the Plan, the number of Shares underlying the Award and all terms governing the Award, including, without limitation, terms
regarding vesting, exercisability and expiration of the Award. Awards may, in the discretion of the Committee, and to the extent permitted by Section 6(a), be made under the Plan to Participants in assumption of, or in substitution for,
outstanding awards previously granted by the Corporation or its affiliates or an entity acquired by the Corporation or with which the Corporation combines. The number of Shares underlying such substitute awards shall be counted against the aggregate
number of Shares available for Awards under the Plan. The Shares underlying such previously outstanding awards, if such awards were Awards under this Plan, shall be added back to the aggregate number of Shares available under the Plan. The Committee
is authorized to interpret the Plan, to establish, amend or rescind any rules and regulations relating to the Plan and to make any other determinations that it deems necessary or desirable for the administration of the Plan. The Committee may
correct any defect or supply any omission or reconcile any inconsistency in the Plan in the manner and to the extent the Committee deems necessary or desirable. Any decision of the Committee in the interpretation and administration of the Plan, as
described herein, shall lie within its sole and absolute discretion and shall be final, conclusive and binding on all parties concerned (including, but not limited to, Participants and their beneficiaries or successors). The Committee shall have the
full power and authority, consistent with the provisions of the Plan, to establish the terms and conditions of any Award and to waive any such terms or conditions at any time (including, without limitation, accelerating or waiving any vesting
conditions). The Committee shall require payment of any amount it may determine to be necessary to withhold for federal, state, local or other taxes as a result of the exercise, grant or vesting of an Award as a condition to such exercise, grant or
vesting. Unless the Committee specifies otherwise, the Participant may elect to pay a portion or all of such withholding taxes by (a) delivery in Shares or (b) having Shares withheld by the Corporation from any Shares that would have
otherwise been received by the Participant. 
  

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 SECTION 5. — Limitations 
 No Award may be granted under the Plan after the tenth anniversary of the Effective Date, but Awards theretofore granted may extend beyond that date. 
 SECTION 6. — Terms and Conditions of Options 
 Options granted under the Plan shall be, as
determined by the Committee, non-qualified or incentive stock options for federal income tax purposes, as evidenced by the related Award agreements between the Corporation and the Option recipient, and shall be subject to the foregoing and the
following terms and conditions and to such other terms and conditions, not inconsistent therewith, as the Committee shall determine: 
 (a) Option Price. The Option Price per Share shall be determined by the Committee, but shall not be less than 100% of the Fair Market Value of the Shares on the date an Option is granted. Notwithstanding any provision in this
Plan to the contrary other than the last sentence of this Section 6(a), no Option may be amended to reduce the per Share Option Price of the Shares subject to such Option below the Option Price determined as of the date the Option is granted,
nor may an Option be granted in exchange for, or in connection with, the cancellation or surrender of an Option or other Award having a higher Option Price or exercise price. The restrictions set forth in this Section 6 shall not apply to the
assumption of, substitution for, or adjustment of outstanding Options that are assumed, substituted, or adjusted in connection with a transaction described in Section 9, provided that the aggregate Option Price times the number of shares
underlying the Option immediately before the transaction equals or exceeds the aggregate Option Price times the number of Shares underlying the Option (or substituted Option) immediately following the transaction. 
 (b) Exercisability. Options granted under the Plan shall be vested and exercisable at such times and upon such terms and
conditions as may be determined by the Committee, but in no event shall an Option be exercisable more than ten years after the date it is granted. 
 (c) Exercise of Options. Except as otherwise provided in the Plan or in an Award agreement, an Option may be exercised for all, or from time to time any part, of the Shares for which it is then vested and
exercisable. For purposes of Section 6 of the Plan, the exercise date of an Option shall be the later of the date a notice of exercise is received by the Corporation and, if applicable, the date payment is received by the Corporation pursuant
to clauses (i), (ii), (iii) or (iv) in the following sentence. The purchase price for the Shares as to which an Option is exercised shall be paid to the Corporation in full at the time of exercise at the election of the Participant
(i) in cash or its equivalent (e.g., by check), (ii) to the extent permitted by the Committee, in Shares having a Fair Market Value equal to the aggregate Option Price for the Shares being purchased and satisfying such other requirements
as may be imposed by the Committee; provided, that such Shares have been held by the Participant for no less than six months (or such other period as established from time to time by the Committee in order to avoid adverse accounting
treatment applying generally accepted accounting principles), (iii) partly in cash and, to the extent permitted by the Committee, partly in such Shares or (iv) if there is a public market for the Shares at such time, subject to rules and
limitations established by the Committee, through the delivery of irrevocable instructions to a broker to sell Shares obtained upon the exercise of the Option and to deliver promptly to the Corporation an amount out of the proceeds of such sale
equal to the aggregate Option Price for the Shares being purchased. No Participant shall have any rights to dividends or other rights of a stockholder with respect to Shares subject to an Option until the Participant has given written notice of
exercise of the Option, paid in full for such Shares, received such Shares from the Corporation and, if applicable, has satisfied any other conditions imposed by the Committee pursuant to the Plan. 
 (d) Incentive Stock Options. The Committee may grant Options under the Plan that are intended to be ISOs. Such ISOs shall
comply with the requirements of Section 422 of the Code (or any successor section thereto). Except as otherwise permitted in Section 422 of the Code (or any successor section thereto), no ISO may be granted to any Participant who, at the
time of such grant, owns more than ten percent of the total combined voting power of all classes of stock of the Corporation or of any Subsidiary, unless (i) the Option Price for such ISO is at least 110% of the Fair Market Value of a Share on
the date the ISO is granted and (ii) the date on which such ISO terminates is a date not later than the day preceding the fifth anniversary of the date on which the ISO is granted. Any Participant who disposes of Shares acquired upon the
exercise of an ISO either (i) within two years after the date of grant of such ISO or (ii) within one year after the transfer of such Shares to the Participant shall promptly notify the Corporation of such disposition and of the amount
realized upon such disposition. All Options granted under the Plan are intended to be nonqualified stock options, unless the applicable Award agreement expressly states that the Option is intended to be an ISO. If an Option is intended to be an ISO,
and if for any reason such Option (or portion thereof) shall not qualify as an ISO, then, to the extent of such failure to qualify, such Option (or portion thereof) shall be regarded as a nonqualified stock option granted under the Plan;
provided, that such Option (or portion thereof) otherwise complies with the Plan’s requirements relating to nonqualified stock options. In no event shall any member of the Committee, the Corporation or any of its Affiliates (or their
respective employees, officers or directors) have any liability to any Participant (or any other Person) due to the failure of an Option to qualify for any reason as an ISO. 
  

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 (e) Attestation. Wherever in this Plan or any agreement evidencing an Award a
Participant is permitted to pay the exercise price of an Option or taxes relating to the exercise of an Option by delivering Shares, the Participant may, subject to procedures satisfactory to the Committee, satisfy such delivery requirement by
presenting proof that he or she is the beneficial owner (as such term is defined in Rule 13d-3 under the Act (or any successor rule thereto)) of such Shares, in which case the Corporation shall treat the Option as exercised without further payment
and shall withhold such number of Shares from the Shares acquired by the exercise of the Option. 
 SECTION 7. — Terms and Conditions of Stock
Appreciation Rights 
 (a) Grants. The Committee also may grant (i) a Stock Appreciation Right
independent of an Option or (ii) a Stock Appreciation Right in connection with an Option, or a portion thereof. A Stock Appreciation Right granted pursuant to clause (ii) of the preceding sentence (A) may be granted at the time the
related Option is granted or at any time prior to the exercise or cancellation of the related Option, (B) shall cover the same number of Shares covered by an Option (or such lesser number of Shares as the Committee may determine) and
(C) shall be subject to the same terms and conditions as such Option except for such additional limitations as are contemplated by this Section 7 (or such additional limitations as may be included in an Award agreement). 
 (b) Terms. The exercise price per Share of a Stock Appreciation Right shall be an amount determined by the Committee but in no
event shall such amount be less than the greater of (i) the Fair Market Value of a Share on the date the Stock Appreciation Right is granted or, in the case of a Stock Appreciation Right granted in conjunction with an Option, or a portion
thereof, the Option Price of the related Option and (ii) the minimum amount permitted by applicable laws, rules, by-laws or policies of regulatory authorities or stock exchanges. Notwithstanding any provision in this Plan to the contrary other
than the next sentence of this Section 7(b), no Stock Appreciation Right may be amended to reduce the exercise price per Share of the Shares subject to such Stock Appreciation Right below the exercise price determined as of the date the Stock
Appreciation Right is granted, nor may a Stock Appreciation Right be granted in exchange for, or in connection with, the cancellation or surrender of a Stock Appreciation Right or other Award having a higher exercise price. The restrictions set
forth in this Section 7(b) shall not apply to the assumption of, substitution for, or adjustment of outstanding Stock Appreciation Rights that are assumed, substituted, or adjusted in connection with a transaction described in Section 9,
provided that the aggregate exercise price times the number of shares underlying the Stock Appreciation Right immediately before the transaction equals or exceeds the aggregate exercise price times the number of Shares underlying the Stock
Appreciation Right (or substituted Stock Appreciation Right) immediately following the transaction. Each Stock Appreciation Right granted independent of an Option shall entitle a Participant upon exercise to an amount equal to (i) the excess of
(A) the Fair Market Value on the exercise date of one Share over (B) the exercise price per Share, times (ii) the number of Shares covered by the Stock Appreciation Right and as to which the Stock Appreciation Right is exercised. Each
Stock Appreciation Right granted in conjunction with an Option, or a portion thereof, shall entitle a Participant to surrender to the Corporation the unexercised Option, or any portion thereof, and to receive from the Corporation in exchange
therefor an amount equal to (i) the excess of (A) the Fair Market Value on the exercise date of one Share over (B) the Option Price per Share, times (ii) the number of Shares covered by the Option, or portion thereof, which is
surrendered. The date a notice of exercise is received by the Corporation shall be the exercise date. Payment shall be made in Shares or in cash, or partly in Shares and partly in cash (any such Shares valued at such Fair Market Value), all as shall
be determined by the Committee. Stock Appreciation Rights may be exercised from time to time in whole or in part upon actual receipt by the Corporation of written notice of exercise stating the number of Shares with respect to which the Stock
Appreciation Right is being exercised. No fractional Shares will be issued in payment for Stock Appreciation Rights, but instead cash will be paid for a fraction or, if the Committee should so determine, the number of Shares will be rounded downward
to the next whole Share. In no event shall a Stock Appreciation Right be exercisable more than ten years after the date it is granted. 
 (c) Limitations. Subject to Section 12, the Committee may impose, in its discretion, such conditions upon the exercisability or transferability of Stock Appreciation Rights as it may deem fit.

 (d) Limited Stock Appreciation Rights. The Committee may grant LSARs that are exercisable upon the occurrence
of specified contingent events (including, without limitation, a Change of Control). Such LSARs may provide for a different method of determining appreciation, may specify that payment will be made only in cash and may provide that any related
Awards are not exercisable while such LSARs are exercisable. Pursuant to Section 4, the Committee is authorized to amend the terms of an LSAR held by any employee subject to Section 16 of the Exchange Act, as may be necessary so that the
holding and exercise of such LSAR will be exempt under such Section 16. Unless the context otherwise requires, whenever the term “Stock Appreciation Right” is used in the Plan, such term shall include LSARs. 
  

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 SECTION 8. — Other Stock-Based Awards 
 (a) Generally. The Committee, in its sole discretion, may grant or sell Awards of Shares, Awards of restricted Shares and
Awards that are valued in whole or in part by reference to, or are otherwise based on the Fair Market Value of, Shares (“Other Stock-Based Awards”). Such Other Stock-Based Awards shall be in such form, and dependent on such conditions, as
the Committee shall determine, including, without limitation, the right to receive, or vest with respect to, one or more Shares (or the equivalent cash value of such Shares) upon the completion of a specified period of service, the occurrence of an
event and/or the attainment of performance objectives; provided, however, that the Committee may grant Awards of unrestricted Shares only if the Committee has determined that such Award is made in lieu of salary or cash bonus. Other
Stock-Based Awards may be granted alone or in addition to any other Awards granted under the Plan. Subject to the provisions of the Plan, the Committee shall determine to whom and when Other Stock-Based Awards will be made, the number of Shares to
be awarded under (or otherwise related to) such Other Stock-Based Awards; whether such Other Stock-Based Awards shall be settled in cash, Shares or a combination of cash and Shares; and all other terms and conditions of such Awards (including,
without limitation, the vesting provisions thereof and provisions ensuring that all Shares so awarded and issued shall be fully paid and non-assessable); provided, however, that the restricted period specified in respect of any Award
of restricted Shares shall not be less than three years, except that the Committee may (i) provide for the restricted period to terminate at any time after one year upon the attainment of performance-based objectives and (ii) the Committee
may grant Awards of up to 500,000 restricted Shares without regard to this limitation. 
 (b) Performance-Based
Awards. Notwithstanding anything to the contrary herein, certain Other Stock-Based Awards granted under this Section 8 may be granted in a manner which is deductible by the Corporation under Section 162(m) of the Code (or any successor
section thereto) (“Performance-Based Awards”). A Participant’s Performance-Based Awards shall be determined based on the attainment of written performance goals approved by the Committee for a performance period established by the
Committee (i) while the outcome for that performance period is substantially uncertain and (ii) no more than 90 days after the commencement of the performance period to which the performance goal relates or, if less, the number of days
which is equal to 25 percent of the relevant performance period, or as otherwise permitted pursuant to Section 162(m) of the Code (or any successor section thereto). The performance goals, which must be objective, shall be based upon one or
more of the following criteria: (i) consolidated earnings before or after taxes (including earnings before interest, taxes, depreciation and amortization); (ii) net income; (iii) operating income; (iv) earnings per Share;
(v) return on shareholders’ equity; (vi) attainment of strategic and operational initiatives; (vii) customer income; (viii) economic value-added models; (ix) maintenance or improvement of profit margins; (x) stock
price, including, without limitation, as compared to one or more stock indices; (xi) market share; (xii) revenues, sales or net sales; (xiii) return on assets; (xiv) book value per Share; (xv) expense management;
(xvi) improvements in capital structure; (xvii) costs and (xviii) cash flow. The foregoing criteria may relate to the Corporation, one or more of its Subsidiaries or one or more of its divisions or units, or any combination of the
foregoing, and may be applied on an absolute basis and/or be relative to one or more peer group companies or indices, or any combination thereof, all as the Committee shall determine. In addition, to the degree consistent with the Code, the
performance goals may be calculated without regard to extraordinary, unusual and/or non-recurring items. The Committee shall determine whether, with respect to a performance period, the applicable performance goals have been met with respect to a
given Participant and, if they have, so certify and ascertain the amount of the applicable Performance-Based Award. No Performance-Based Awards will be paid for such performance period until such certification is made by the Committee. The amount of
the Performance-Based Award actually paid to a given Participant may be less than the amount determined by the applicable performance goal formula, at the discretion of the Committee. The amount of the Performance-Based Award determined by the
Committee for a performance period shall be paid to the Participant at such time as determined by the Committee in its sole discretion after the end of such performance period; provided, however, that a Participant may, if and to the
extent permitted by the Committee and consistent with the provisions of Section 162(m) of the Code, elect to defer payment of a Performance Based Award. To the extent Section 162(m) of the Code (or any successor section thereto) provides
terms different from the requirements of this Section 8(b), this Section 8(b) shall be deemed amended thereby. 
 SECTION 9. — Adjustments
Upon Certain Events 
 Notwithstanding any other provisions in the Plan to the contrary: 
 (a) Generally. In the event after the Effective Date there is any Share dividend or split, reorganization, recapitalization,
merger, consolidation, spin-off, combination, combination or transaction or exchange of Shares or other corporate exchange, or any distribution to shareholders of Shares or other property or securities (other than regular cash dividends) or any
transaction similar to the foregoing or other transaction that results in a change to the Corporation’s equity capitalization, the Committee shall make such substitution or adjustment, if any, as is equitable or appropriate, as to (i) the
number or kind of Shares or other securities issued or reserved for issuance pursuant to the Plan or pursuant to outstanding Awards, (ii) the maximum number of Shares for which Options and Stock Appreciation 

  

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Rights and Other Stock-Based Awards under Section 8(b) may be granted during a calendar year to any Participant, (iii) the maximum number of Shares
which may be granted as Awards of restricted Shares, unrestricted Shares and restricted Share units, (iv) the Option Price, exercise price of any Stock Appreciation Right or purchase price of any Award and/or (v) any other affected terms
of an Award or the Plan. 
 (b) Change of Control. In the event of a Change of Control after the Effective Date,
except to the extent the Committee has determined otherwise with respect to any Award at or prior to the time of grant, (i) any outstanding Awards then held by Participants which are unexercisable or otherwise unvested or subject to lapse
restrictions shall automatically be deemed exercisable or otherwise vested or no longer subject to lapse restrictions, as the case may be, as of immediately prior to the effectiveness of such Change of Control and (ii) the Committee may, but
shall not be obligated to, (A) cancel such Awards for fair value (as determined in the sole discretion of the Committee) which, in the case of Options and Stock Appreciation Rights, may equal the excess, if any, of value of the consideration to
be paid in the Change of Control transaction to holders of the same number of Shares subject to such Options or Stock Appreciation Rights (or, if no consideration is paid in any such transaction, the Fair Market Value of the Shares subject to such
Options or Stock Appreciation Rights) over the aggregate exercise price of such Options or Stock Appreciation Rights or (B) provide for the issuance of substitute Awards that will substantially preserve the otherwise applicable terms of any
affected Awards previously granted hereunder as determined by the Committee in its sole discretion. 
 SECTION 10. — No Right to Employment or
Awards; Excluded Compensation Under Other Plans 
 The granting of an Award under the Plan shall impose no obligation on the Corporation
or any Subsidiary to continue the employment of a Participant and shall not lessen or affect the Corporation’s or Subsidiary’s right to terminate the employment of such Participant. No Participant or other Person shall have any claim to be
granted any Award, and there is no obligation for uniformity of treatment of Participants or holders or beneficiaries of Awards. The terms and conditions of Awards and the Committee’s determinations and interpretations with respect thereto need
not be the same with respect to each Participant (whether or not such Participants are similarly situated). No award under the Plan shall be taken into account in determining a Participant’s compensation for purposes of any group life insurance
or other employee benefit or pension plan of the Corporation. 
 SECTION 11. — Successors and Assigns 
 The Plan shall be binding on all successors and assigns of the Corporation and a Participant, including, without limitation, the estate of such
Participant and the executor, administrator or trustee of such estate, or any receiver or trustee in bankruptcy or representative of the Participant’s creditors. 
 SECTION 12. — Transferability of Awards 
 An Award shall not be transferable or assignable by the
Participant for consideration. An Award may be transferred by will or by the laws of descent and distribution. An Award exercisable after the death of a Participant may be exercised by the legatees, personal representatives or distributees of the
Participant. Upon the Disability of a Participant, an Award may be exercisable by his or her conservator or representative. At the Committee’s discretion, an Award agreement may provide that a Participant may transfer certain Awards to family
members, or one or more trusts or other entities for the benefit of or owned by family members, consistent with applicable securities laws, provided that the Participant receives no consideration for the transfer of the Award and the transferred
Award shall continue to be subject to the same terms and conditions as were applicable to the Award immediately before the transfer. 
 SECTION 13. —
Share Issuance and Delivery in Compliance With Securities Laws 
 If in the opinion of counsel for the Corporation (who may be an employee
of the Corporation or independent counsel employed by the Corporation), any issuance or delivery of Shares to a Participant will violate the requirements of any applicable federal or state laws, rules or regulations (including, without limitation,
the provisions of the Securities Act of 1933, as amended, or the Act), such issuance or delivery may be postponed until the Corporation is satisfied that the distribution will not violate such laws, rules or regulations. Certificates delivered to
Participants pursuant to the Plan may bear such legends as the Corporation may deem advisable. 
 SECTION 14. — Amendments or Termination

 The Board may amend the Plan at any time, provided that no amendment shall be made without the approval of the Shareholders of the
Corporation that would (a) increase the maximum number of Shares which may be acquired under the Plan, (b) extend the term during which Options may be granted under the Plan, (c) permit the Option Price or exercise price per Share to
be less than 100% of the Fair Market Value of the Shares on the date an Option or Stock Appreciation Right is granted (other than as specifically provided in Sections 6(a) and 7(b)), (d) terminate restrictions applicable to Awards (except for
Permitted Exceptions) or (e) provide for Awards not permitted pursuant to the terms of the Plan. The Board shall also have the right to terminate the Plan at any time. Without the consent of a Participant (except as otherwise provided in

  

 7 

 
Section 9(a)), no amendment shall materially diminish any of the rights of such Participant under any Award theretofore granted to such Participant
under the Plan; provided, however, that the Committee may amend the Plan in such manner as it deems necessary to permit the granting of Awards meeting the requirements of the Code or other applicable laws. 
 SECTION 15. — International Participants 
 With
respect to Participants who reside or work outside the United States of America and who are not (and who are not expected to be) “covered employees” within the meaning of Section 162(m) of the Code, the Committee may, in its sole
discretion, amend the terms of the Plan or Awards with respect to such Participants in order to conform such terms with the provisions of local law and practice or otherwise as deemed necessary or desirable by the Committee. 
 SECTION 16. — Choice of Law 
 The Plan shall be
governed by and construed in accordance with the laws of the State of New Jersey without regard to conflicts of laws. 
 SECTION 17. — Effectiveness
of the Plan 
 The Plan shall be effective as of the Effective Date. 
  

 8THIRD WAVE TECHNOLOGIES, INC. 1999 INCENTIVE STOCK OPTION PLAN

 Exhibit 10.1 
 THIRD WAVE TECHNOLOGIES, INC. 
 1999 INCENTIVE STOCK OPTION PLAN 
  
  
  

	1.	Purpose. The purpose of the Third Wave Technologies, Inc. 1999 Incentive Stock Option Plan (the “Plan) is to encourage certain employees of Third Wave Technologies, Inc.
(the “Corporation”) to acquire or increase their stock ownership in the Corporation, to provide an incentive to such employees to promote the financial success of the Corporation, and to enable the Corporation to attract and retain
personnel necessary for continued growth and profitability. 

  

	2.	Effective Date and Term of Plan. The Plan shall become effective on the date adopted by the Board of Directors of the Corporation (“Board of Directors”) and shall
continue for a period of ten years unless sooner terminated as provided in Paragraph 17. 

  

	3.	Approval of Shareholders. The Plan is subject to the approval of shareholders of majority of all of the outstanding voting shares of the Corporation. If it is not so approved
on or before one year after the date of adoption of the Plan by the Board of Directors, the Plan shall not come into effect and any options granted pursuant to the Plan shall be deemed canceled. No option may be exercised prior to approval of the
Plan by the shareholders. 

  

	4.	Stock Subject to Plan. Only Common Stock, with $1.00 par value per share, of the Corporation (“Common Stock”) may be issued pursuant to options granted under this
Plan. The maximum number of shares of Common Stock that may be issued pursuant to the exercise of options granted under the Plan (“Options”) is Four Hundred Fifty-nine (459) shares of Common Stock, less the number of shares of Common
Stock that may be issued pursuant to the Third Wave Technologies, Inc. 1999 Nonqualified Stock Option Plan effective as of the date of this Plan, subject to any adjustments provided in Paragraph 16. If any Options expire or terminate for any reason
without having been exercised in full, the unpurchased shares subject thereto shall again be available for further grants under the Plan. 

  

	5.	 Administration. The Plan shall be administered by the committee described in Paragraph 6 (the “Committee”). Subject to the express provisions of
the Plan, the Committee shall have complete authority in its discretion, to determine those employees (“Participants”) to whom Options shall be granted, the option price, the option periods and the number of shares to be subject to each
Option. Subject to the express provisions of the Plan, the Committee shall also have the authority in its discretion to prescribe the time or times at which Options may be exercised, the limitations upon the exercise of Options (including
limitations effective upon death, disability, or termination of employment of any Participant) and the restrictions, if any, to be imposed upon the transferability of shares acquired upon exercise of Options. In making such determinations, the
Committee may take into account the nature of the services rendered by the respective Participants, their present and potential contributions to the success of the Corporation, and such other factors as the Committee in its discretion shall deem
relevant. Subject to the express provisions of the Plan, the Committee shall also have complete authority to interpret the Plan, to prescribe, amend and rescind rules and regulations relating to the Plan, to determine the terms and provisions of the
respective option agreements (which need not be identical), to determine whether the shares delivered upon exercise of Options will be treasury shares or will be authorized but previously unissued shares and to make all other determinations
necessary or advisable for the 

	 	 
administration of the Plan. The Committee’s determinations on the matters referred to in this paragraph shall be conclusive.

  

	6.	Committee. The Committee shall consist of not less than two members of the Board of Directors, each of whom shall be (i) a “non-employee director” as that term
is defined in Rule 16b-3 promulgated under the Securities and Exchange Act of 1934, as amended (the “Exchange Act”), and (ii) an “outside director” within the meaning of Section 162(m) of the Internal Revenue Code of
1986, as amended (the “Code”). The Committee shall be appointed from time to time by the Board of Directors, which may from time to time appoint members of the Committee in substitution for members previously appointed and may fill
vacancies, however caused, in the Committee. A majority of its members shall constitute a quorum. All determinations of the Committee shall be made by a majority of its members. Any decision or determination reduced to writing and signed by all of
the members shall be fully as effective as if it had been made by a majority vote at a meeting duly called and held. The Committee may hold meetings by use of conference telephone or similar communications equipment by which all persons
participating in the meeting can hear each other. 

  

	7.	Eligibility. An Option may be granted under the Plan to any employee of the Corporation, and of its present and future subsidiaries, as defined in Section 424(f) of the
Code (“Subsidiaries”). The foregoing nonwithstanding, members of the Committee shall not, while serving as members of the Committee, be eligible to receive Options. 

  

	8.	Option Price. The option price per share will be determined by the Committee at the time each Option is granted, but shall not be less than 100% of the fair market value, as
determined by the Committee, of a share of Common Stock on the date of grant. If such Option is granted to a person who owns, directly or indirectly, stock possessing more than 10% of the total combined voting power of all classes of stock of the
Corporation on the date of the grant, the option price per share shall not be less than 110% of its fair market value. 

  

	9.	Option Periods. The term of each Option will be for such period not exceeding ten years from the date of grant, as the Committee shall determine; provided, however, that if
such Option is granted to a person who owns, directly or indirectly, stock possessing more than 10% of the total combined voting power of all classes of stock of the Corporation on the date of the grant, the term of such Option shall not exceed five
years from the date of grant. An Option shall be considered granted on the date the Committee acts to grant the Option or such later date as the Committee shall specify. Each Option shall be subject to earlier termination as described under
Paragraphs 13 and 17. 

  

	10.	Exercise of Options. Subject to the restrictions in Paragraph 13 and in the agreement referred to in Paragraph 14, each Option may be exercised at any time during the option
period for such Option by written notice delivered to an officer of the Corporation, stating the number of shares with respect to which the Option is being exercised. 

  

	11.	 Payment for Option. Within five (5) business days following the date of exercise, the Participant shall make full payment of the option price
(i) in cash; (ii) with the consent of the Committee, by tendering previously acquired shares of Common Stock which on the date of tender (A) have a fair market value, as determined by the Committee equal to the aggregate option price
and (B) in the case of shares acquired by previous exercise of an option, have been owned by the Participant for more than six months; or (iii) any combination of (i) and (ii). Shares of Common Stock tendered shall be duly endorsed in
blank or accompanied by 

  

 - 2 - 

	 	 
stock powers duly endorsed in blank. Upon receipt of the payment of the entire option price for the shares so purchased, certificates for such shares shall
be delivered to the Participant. The transferability of such shares shall be subject to the restrictions contained in the Shareholder Agreement in the form attached hereto and made part hereof as Exhibit A, or as otherwise may be required by the
Committee from time to time, and the Participant agrees to execute such documents as may be required by the Corporation to become an “Agreeing Shareholder” as such term is defined in the Shareholder Agreement. 

 

	12.	Maximum Per Participant. The aggregate fair market value, as determined by the Committee, of the stock for which options held by a Participant are exercisable for the first
time under the Plan or other options granted to the Participant under any plan of the Corporation or any Subsidiary during any calendar year shall not exceed $100,000. For purposes of this paragraph, the fair market value of stock subject to an
Option or other Incentive Stock Option shall be determined as of the date the Option or other Incentive Stock Option, as the case may be, is granted. 

  

	13.	Termination of Employment. Except as hereinafter provided, no Option may be exercised later than three months after a Participant terminates his employment with the
Corporation or its Subsidiaries, as the case may be. If termination of employment results from the deliberate, willful or gross misconduct of a Participant, then the Option may not be exercised and all of the Participant’s rights in the Option
shall be forfeited upon termination. If termination of employment results from the disability of a Participant within the meaning of Section 22(e)(3) of the Code, as amended, any Option may be exercised at any time within twelve months after
such termination of employment, but in no event beyond the option period. If termination of employment results from the death of a Participant, the personal representative of the Participant’s estates, or a person who by bequest, inheritance,
or otherwise by reason of the Participant’s death, acquired the right to exercise the Option, may exercise any Option at any time within three years after the death of such Participant, but in no event beyond the option period. The Committee
may impose additional restrictions upon the exercise of Options after termination of employment, including prohibition of such exercise. 

  

	14.	Agreements. Options granted pursuant to the Plan shall be evidenced by a stock option agreement in the form attached hereto as Exhibit B, or as otherwise may be required by
the Committee from time to time, except that in the case of a “Key Employee”, as defined in Paragraph 17 below, the stock option agreement will include such different or additional terms as are required by Paragraph 17 below and the 1999
Investment Agreement, also as defined in Paragraph 17 below. 

  

	15.	Nontransferability of Options. Options under the Plan are not transferable by a Participant other than by will or the laws of descent or distribution, and may be exercised
during the lifetime of a Participant only by such Participant. 

  

	16.	 Adjustment of Number of Shares. In the event of any change in the outstanding Common Stock of the Corporation by reason of stock dividends,
recapitalizations, reorganizations, mergers, consolidations, split-ups, combinations or exchanges of shares and the like, the Committee shall, consistent with such change, appropriately adjust the number and kind of shares which thereafter may be
optioned and sold under the Plan, the number and kind of shares under option in outstanding and sold under the Plan, the number and kind of shares under option in outstanding stock option agreements and the purchase price per share thereof. The
determination of the Committee as to any such adjustment shall be final and conclusive. No adjustment or substitution provided for in this paragraph shall require the 

  

 - 3 - 

	 	 
Corporation in any stock option agreement to sell a fractional share and the total substitution or adjustment with respect to each stock option agreement
shall be limited accordingly. 

  

	17.	Change in Control. In the case of a Key Employee, as the term is defined in the Investment Agreement dated as of July 21, 1999, by and among the Corporation and
Schroeder Ventures International Life Sciences Fund II et al (the “1999 Investment Agreement”), the terms of his or her stock option agreement shall further provide that in the event of an Adjustment to the Applicable Conversion Value
pursuant to Sections 5.5(a) or 5.5(e) of Article III of the Corporation’s Amended and Restated Articles of Incorporation (the “Articles”), but not an Adjustment to the Applicable Conversion Value as a result of a Below Projection
Liquidity Event pursuant to section 5.5(h) of Article III of the Articles, all rights of the holder of the Option shall automatically terminate and holder of the Option shall automatically forfeit such Option to the Corporation and, to the extent
such Option has been previously exercised, the holder shall automatically forfeit any such shares received upon such prior exercise, provided that in such event the Corporation shall reimburse the holder thereof for all consideration previously paid
to the Corporation upon the exercise of such Option. 

  

	18.	Amendment, Suspension or Termination. The Board of Directors, without further approval of the shareholders, may from time to time amend, suspend or terminate the Plan in such
respects as the Board may deem advisable; provided, however, that no amendment shall become effective without prior approval of the shareholders which would (i) increase the aggregate number of shares which may be issued pursuant to Options
granted under the Plan, except as permitted under Paragraph 16; (ii) permit the granting of options to anyone other than an employee of the Corporation or a Subsidiary or to a member of the Committee; (iii) decrease the minimum option
prices; (iv) increase the maximum option periods; (v) increase the maximum per Participant set in Paragraph 12; or (vi) extend the term of the Plan. No amendment shall, without the Participant’s consent, alter or impair any of
the rights or obligations under any Option theretofore granted to the Participant. 

 Dated this 7th day of October, 1999. 
  

			
	THIRD WAVE TECHNOLOGIES, INC.
		
	By:	 	 
		 	         Lance Fors, President and
         Chief Executive Officer

  
  

			
		
	Attest:	 	 
		 	     David C. Sneider,
     Chief Financial Officer

  

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