Document:

Form of senior debt security

 Exhibit 4.01 
 LEHMAN BROTHERS HOLDINGS INC. 
 Partial Protection Participation Notes Linked to a Basket of Global Index Funds Due
June 5, 2010 
  

			
	Number R-1	 	$1,320,000
	ISIN US5252M0GE18	 	CUSIP 5252M0GE1

 See Reverse for Certain Definitions 
 THIS SECURITY (THIS “SECURITY”) IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN
THE NAME OF A DEPOSITORY OR A NOMINEE THEREOF. UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN CERTIFICATED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITORY TO A NOMINEE OF THE DEPOSITORY OR BY A
NOMINEE OF THE DEPOSITORY TO SUCH DEPOSITORY OR ANOTHER NOMINEE OF THE DEPOSITORY OR BY THE DEPOSITORY OR ANY SUCH NOMINEE TO A SUCCESSOR DEPOSITORY OR A NOMINEE OF SUCH SUCCESSOR DEPOSITORY. UNLESS THIS SECURITY IS PRESENTED BY AN AUTHORIZED
REPRESENTATIVE OF THE DEPOSITORY TO LEHMAN BROTHERS HOLDINGS INC. OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY SECURITY ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS REQUESTED BY AN
AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY (AND ANY PAYMENT IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE
BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 
 LEHMAN BROTHERS
HOLDINGS INC., a corporation duly organized and existing under the laws of the State of Delaware (hereinafter called the “Company”), for value received, hereby promises to pay to CEDE & CO. or registered assigns, at the
office or agency of the Company in the Borough of Manhattan, The City of New York, on the Maturity Date, in such coin or currency of the United States of America at the time of payment shall be legal tender for the payment of public and private
debts, for each $1,000 principal amount of the Securities represented hereby, an amount equal to the Payment at Maturity. THE SECURITIES REPRESENTED HEREBY SHALL NOT BEAR ANY INTEREST. 
 Any amount payable hereon on the Maturity Date will be paid only upon presentation and surrender of this Security. 
 REFERENCE IS HEREBY MADE TO THE FURTHER PROVISIONS OF THIS SECURITY SET FORTH ON THE REVERSE HEREOF WHICH FURTHER PROVISIONS SHALL FOR ALL PURPOSES HAVE
THE SAME EFFECT AS IF SET FORTH AT THIS PLACE. 

 This Security shall not be valid or become obligatory for any purpose until the certificate of
authentication hereon shall have been signed by the Trustee under the Indenture referred to on the reverse hereof. 
 “Standard & Poor’s®”, “S&P®” and “S&P 500®” are trademarks of The McGraw-Hill Companies, Inc. and are expected to be licensed for use by the Company. The Company is expected to enter into a non-exclusive license agreement with Standard &
Poor’s (“S&P”), a division of The McGraw Hill Companies, Inc. for use of “Standard & Poor’s Depositary Receipts®” and “SPDR®” which are also trademarks of The McGraw-Hill Companies, Inc. The Securities, which are linked to the performance of the SPDR Trust, Series 1, are not sponsored, endorsed, sold or promoted
by S&P, State Street Bank and Trust Company, as trustee for the Index Fund (“SSBTC”) and PDR Services LLC, as sponsor of the SPDR Trust, Series 1 (the “Index Fund Sponsor”). S&P, SSBTC and the Index Fund Sponsor makes no
representation regarding the advisability of investing in the Securities. S&P has no obligation or liability in connection with the operation, marketing, trading or sale of the Securities. 
 “iShares®” is a registered mark of Barclays Global Investors, N.A.
(“BGI”). BGI has licensed certain trademarks and trade names of BGI to the Company. The Securities, linked to the performance of the iShares® MSCI EAFE Index Fund, are not
sponsored, endorsed, sold or promoted by BGI. BGI makes no representations or warranties to the Holders of the Securities or any member of the public regarding the advisability of investing in the Securities. BGI has no obligation or liability in
connection with the operation, marketing, trading or sale of the Securities. 
 “MSCI EAFE Index®” is a registered trademark of MSCI, Inc. (“MSCI”) and is expected to be licensed for use by the Company. The Securities which are linked to the performance of the iShares® MSCI EAFE Index Fund, are not sponsored, endorsed, sold or promoted by MSCI, and MSCI makes no representation regarding the advisability of investing in the Securities. 
 “Russell 2000® Index” is a registered trademark of Russell Investment Group
(“Russell”) and has been licensed for use by the Company. The Securities, which are linked to the performance of the iShares® Russell 2000 Index Fund, are not sponsored, endorsed,
sold or promoted by Russell, and Russell makes no representation regarding the advisability of investing in the Securities. 
  

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 IN WITNESS WHEREOF, Lehman Brothers Holdings Inc. has caused this instrument to be signed by its
Chairman of the Board, its President, its Vice Chairman, its Chief Financial Officer, one of its Vice Presidents or its Treasurer, by manual or facsimile signature under its corporate seal, attested by its Secretary or one of its Assistant
Secretaries by manual or facsimile signature. 
  

							
	Dated: June 5, 2008	 	LEHMAN BROTHERS HOLDINGS INC.	 	
				
	[SEAL]	 	By:	 	  
	 	
		 		 	Vice President	 	
				
		 	Attest:	 	  
	 	
		 		 	Assistant Secretary	 	

  
 TRUSTEE’S CERTIFICATE OF
AUTHENTICATION 
 This is one of the Securities of the series designated therein referred to in the within-mentioned Indenture. 
  

			
	 CITIBANK, N.A.
 as
Trustee

		
	By:	 	  

		 	    Authorized Officer

  

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 Reverse of Security 
 This Security is one of a duly authorized series of Securities of the Company designated as Partial Protection Participation Notes Linked to a Basket of Global Index Funds Due June 5, 2010 (herein called the
“Securities”). The Company may, without the consent of the holders of the Securities, create and issue additional securities ranking equally with the Securities and otherwise similar in all respects so that such additional
securities shall be consolidated and form a single series with the Securities; provided that no additional securities can be issued if an Event of Default has occurred with respect to the Securities. This series of Securities is one of an indefinite
number of series of debt securities of the Company, issued and to be issued under an indenture, dated as of September 1, 1987, as amended (herein called the “Indenture”), duly executed and delivered by the Company and Citibank,
N.A., as trustee (herein called the “Trustee”, which term includes any successor trustee under the Indenture), to which Indenture and all indentures supplemental thereto reference is hereby made for a description of the rights,
limitations of rights, obligations, duties and immunities thereunder of the Company, the Trustee and the Holders of the Securities. 
 The
Payment at Maturity shall, at the request of the Trustee be determined by the Calculation Agent pursuant to the Calculation Agency Agreement. The Trustee shall fully rely on the determination by the Calculation Agent of the Payment at Maturity and
shall have no duty to make any such determination. At or prior to 11:00 a.m. on the Business Day preceding the Maturity Date, the Calculation Agent will provide written notice to the Trustee at its New York office, on which notice the Trustee may
conclusively rely, of the Payment at Maturity. 
 All calculations with respect to each Basket Index Fund Return, the Basket Ending Level
and the Basket Return will be rounded to the nearest one hundred-thousandth, with five one-millionths rounded upward (e.g., .876545 would be rounded to .87655); all dollar amounts related to determination of the payment per $1,000 principal
amount Security on the Maturity Date, if any, will be rounded to the nearest ten-thousandth, with five one hundred-thousandths rounded upward (e.g., .76545 would be rounded up to .7655); and all dollar amounts paid on the aggregate principal
amount of Securities per Holder will be rounded to the nearest cent, with one-half cent rounded upward. 
 This Security is not subject to
any sinking fund. 
 If an Event of Default with respect to the Securities shall occur and be continuing, the amounts payable on all of the
Securities may be declared due and payable in the manner and with the effect provided in the Indenture. The amount payable to the Holder hereof upon any acceleration permitted under the Indenture will be equal to the Payment at Maturity calculated
as though the date of acceleration were the Maturity Date and the third Business Day immediately preceding the date of acceleration were the Valuation Date. If the maturity of the Securities is accelerated because of an Event of Default, the Company
shall, or shall cause the Calculation Agent to, provide written notice to the Trustee at its New York office, on which notice the Trustee may conclusively rely, and to The Depository Trust Company of the cash amount due with respect to the
Securities as promptly as possible and in no event later than two Business Days after the date of acceleration. 

 The Indenture contains provisions permitting the Company and the Trustee, with the consent of the
holders of not less than 66 2/3% in aggregate principal amount of the Outstanding Securities (as defined in the Indenture) of
each series affected by a proposed supplemental indenture (each series voting as a class), evidenced as provided in the Indenture, to execute such supplemental indenture for the purpose of adding any provisions to, or changing in any manner or
eliminating any provisions of, the Indenture or of any supplemental indenture or, modifying in any manner the rights of the holders of the Securities of all such series; provided, however, that no such supplemental indenture
shall, among other things, (i) change the fixed maturity of any Security, or reduce the principal amount thereof, or reduce the rate or extend the time of payment of interest thereon, if any, or reduce any premium payable on redemption, or make
the principal thereof, or premium, if any, or interest thereon, if any, payable in any coin or currency other than that hereinabove provided, without the consent of the holder of each Outstanding Security so affected, or (ii) change the place
of payment on any Security, or impair the right to institute suit for payment on any Security, or reduce the aforesaid percentage of Securities, the holders of which are required to consent to any such supplemental indenture, without the consent of
the holders of each Outstanding Security so affected. It is also provided in the Indenture that, prior to any declaration accelerating the maturity of any series of Securities, the holders of a majority in aggregate principal amount of the
Securities of such series Outstanding may on behalf of the holders of all the Securities of such series waive any past default or Event of Default under the Indenture with respect to such series and its consequences, except a default in the payment
of interest, if any, or the principal of, or premium, if any, on any of the Securities of such series, or in the payment of any sinking fund installment or analogous obligation with respect to Securities of such series. Any such consent or waiver by
the Holder of this Security shall be conclusive and binding upon such Holder and upon all future holders and owners of this Security and any Securities which may be issued in exchange or substitution hereof, irrespective of whether or not any
notation thereof is made upon this Security or such other Securities. 
 No reference herein to the Indenture and no provision of
this Security or of the Indenture shall alter or impair the obligation of the Company, which is absolute and unconditional, to pay the Payment at Maturity with respect to this Security. 
 The Securities are issuable in denominations of $1,000 and any whole multiples thereof. 
 The Company, the Trustee, and any agent of the Company or of the Trustee may deem and treat the registered holder (the “Holder”) hereof
as the absolute owner of this Security (whether or not this Security shall be overdue and notwithstanding any notation of ownership or other writing hereon), for the purpose of receiving payment hereof, or on account hereof, and for all other
purposes and neither the Company nor the Trustee nor any agent of the Company or of the Trustee shall be affected by any notice to the contrary. All such payments made to or upon the order of such registered holder shall, to the extent of the sum or
sums paid, effectually satisfy and discharge liability for moneys payable on this Security. 
 No recourse for the payment of the principal
of, or premium, if any, on this Security, or for any claim based hereon or otherwise in respect hereof, and no recourse under or upon any obligation, covenant or agreement of the Company in the Indenture or any indenture 

  

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supplemental thereto or in any Security, or because of the creation of any indebtedness represented thereby, shall be had against any incorporator,
stockholder, officer or director, as such, past, present or future, of the Company or of any successor corporation, either directly or through the Company or any successor corporation, whether by virtue of any constitution, statute or rule of law or
by the enforcement of any assessment or penalty or otherwise, all such liability being, by the acceptance hereof and as part of the consideration for the issue hereof, expressly waived and released. 
 As provided in the Indenture and subject to certain limitations therein set forth, the transfer of this Security is registrable in the Security
Register, upon surrender of this Security for registration of transfer at the Corporate Trust Office or agency in a Place of Payment for this Security, duly endorsed by, or accompanied by a written instrument of transfer in form satisfactory to the
Company and the Security Registrar duly executed by, the Holder hereof or such Holder’s attorney duly authorized in writing, and thereupon one or more new Securities of this series or of like tenor and of authorized denominations and for the
same aggregate principal amount, will be issued to the designated transferee or transferees. 
 The Company intends to treat, and by
purchasing this Security, the Holder agrees to treat, for all tax purposes, this Security as a cash-settled financial contract, rather than as a debt instrument. 
 THE INDENTURE AND THIS SECURITY SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK. 
 Definitions 
 Set forth below are definitions of the terms used in this Security. 
 “Basket” shall mean the basket of three index funds to which the Securities are linked. The Basket shall initially be composed of the
SPDR Trust, Series 1, the iShares® MSCI EAFE Index Fund and the iShares® Russell 2000 Index Fund (each, a “Basket Index
Fund” and, collectively, the “Basket Index Funds”). 
 “Basket Ending Level”, as calculated by the
Calculation Agent, is calculated as follows: 
 Basket Starting Level × [1 + (the sum of (Basket Index Fund Return × Basket
Index Fund Weighting) for all Basket Index Funds)] 
 “Basket Index Fund” shall initially be the SPDR Trust, Series 1, the
iShares® MSCI EAFE Index Fund and the iShares® Russell 2000 Index Fund (each, a “Basket Index Fund” and, collectively,
the “Basket Index Funds”). 
 “Basket Index Fund Final Share Price” shall mean, with respect to each Basket Index
Fund, the Closing Price of the Basket Index Fund on the Valuation Date. 
  

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 “Basket Index Fund Initial Share Price” for each Basket Index Fund shall equal the
Closing Price of such Basket Index Fund on the Pricing Date, divided by the applicable Share Adjustment Factor. The Basket Index Fund Initial Share Price of each Basket Index Fund shall initially be as follows: 
  

			
	 Basket Index Fund
	  	 Basket Index Fund
 Initial Share Price

	 SPDR Trust, Series 1
 iShares® MSCI EAFE Index Fund
 iShares® Russell 2000 Index
Fund
	  	 $138.90
 $75.91
 $73.99

 “Basket Index Fund Return” for each Basket Index Fund, as calculated by the
Calculation Agent, shall be calculated as follows: 
 Basket Index Fund Final Share Price – Basket Index Fund Initial Share Price 

 Basket Index Fund Initial Share Price 
 “Basket Index Fund Weighting” shall mean, with respect to each Basket Index Fund, the weighting for such Basket Index Fund. The Basket Index Fund Weighting for each Basket Index Fund shall be as follows: 
  

			
	 Basket Index Fund
	  	 Basket Index Fund
 Weighting

	 SPDR Trust, Series 1
 iShares® MSCI EAFE Index Fund
 iShares® Russell 2000 Index
Fund
	  	 45.00%
 40.00%
 15.00%

 “Basket Return”, as calculated by the Calculation Agent, is calculated as
follows: 
 Basket Ending Level – Basket Starting Level 
 Basket Starting Level 
 “Basket Starting Level” shall equal 1,000.

 “Buffer Amount” shall equal 10.00%. 
 “Business Day”, notwithstanding any provision in the Indenture, shall mean any day that is not a Saturday or Sunday and that is not a day on which banking institutions in the City of New York are
authorized or obligated by law to close. 
 “Calculation Agency Agreement” shall mean the Calculation Agency Agreement,
dated as of December 21, 2006 between the Company and the Calculation Agent, as amended from time to time, or any successor calculation agency agreement. 
  

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 “Calculation Agent” shall mean the person that has entered into an agreement with the
Company providing for, among other things, the determination of the Payment at Maturity, which term shall, unless the context otherwise requires, include its successors and assigns. The initial Calculation Agent shall be Lehman Brothers Inc.

 “Closing Price” shall mean, as to one share of any Basket Index Fund (or any Successor Basket Index Fund) or one unit of
any other security for which a Closing Price must be determined on any Trading Day: 
  

	 	•	 	 if such Basket Index Fund (or any such Successor Basket Index Fund or such other security) is listed or admitted to trading on a national securities exchange, the
last reported sale price, regular way, of the principal trading session on such day on the principal United States securities exchange registered under the Securities Exchange Act of 1934 (the “Exchange Act”) on which such Basket Index
Fund (or any such Successor Basket Index Fund or such other security) is listed or admitted to trading; 

  

	 	•	 	 if such Basket Index Fund (or any such Successor Basket Index Fund or such other security) is listed or admitted to trading on any national securities exchange but
the last reported sale price is not available pursuant to the preceding bullet point, the last reported sale price of the principal trading session on the over-the-counter market as reported on the OTC Bulletin Board Service (the “OTC Bulletin
Board”) operated by Financial Industry Regulatory Authority, Inc. (“FINRA”) on such day; 

  

	 	•	 	 if such Basket Index Fund (or any such Successor Basket Index Fund or such other security) is not listed or admitted to trading on any national securities exchange
but is included in the OTC Bulletin Board, the last reported sale price of the principal trading session on the OTC Bulletin Board on such day; 

  

	 	•	 	 if such Basket Index Fund (or any such Successor Basket Index Fund) is de-listed, liquidated or otherwise terminated, the Closing Price calculated pursuant to the
alternative methods of calculation of the Closing Price described below under “Alternative Calculation of Closing Price”; or 

  

	 	•	 	 if, because of a Market Disruption Event or otherwise, the last reported sale price for such Basket Index Fund (or any such Successor Basket Index Fund or such
other security) is not available for such Trading Day pursuant to the preceding bullet points, then (i) if the day for which such last reported sale price is unavailable is other than the Valuation Date, the calculation agent’s good faith
estimate of the price of a share of such 

  

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Basket Index Fund (or such other security) as of the close of trading on such trading day, in its sole discretion, and (ii) if the day for which such
last reported sale price is unavailable is the originally scheduled Valuation Date with respect to such Basket Index Fund, the price determined pursuant to the final sentence of the definition of “Valuation Date,”

 in each case subject to the provisions of “Alternative Calculation of Closing Price” below. 
 “Company” shall have the meaning set forth on the face of this Security. 
 “Holder” shall have the meaning set forth on the reverse of this Security. 
 “Indenture” shall have the meaning set forth on the reverse of this Security. 
 “Market Disruption Event” shall mean, with respect to any Basket Index Fund (or any Successor Basket Index Fund or other security for
which a Closing Price must be determined) on any day, any of the following events on such day, as determined by the Calculation Agent: 
 (1) the occurrence or existence of a suspension, absence or material limitation of trading of the shares of such Basket Index Fund (or such Successor Basket Index Fund or such other security) on the primary market for such shares (or such
Successor Basket Index Fund or such other security) at any time during the one-hour period preceding the close of the principal trading session in such market; or 
 (2) a breakdown or failure in the price and trade reporting systems of the primary market for the shares of such Basket Index Fund (or such Successor Basket Index Fund or such other security) as a result of which the
reported trading prices for such shares (or such Successor Basket Index Fund or such other security) during the last one-hour period preceding the close of the principal trading session in such market are materially inaccurate; or 
 (3) the occurrence or existence of a suspension, absence or material limitation of trading on the primary market for trading in futures or options
contracts related to the shares of such Basket Index Fund (or such Successor Basket Index Fund or such other security), if available, during the last one-hour period preceding the close of the principal trading session in the applicable market; or

 (4) the occurrence or existence of a suspension, absence or material limitation of trading of stocks then constituting 20% or more of the
level of the related Underlying Index (or the underlying index related to such Successor Basket Index Fund) on the Relevant Exchanges for such stocks at any time during the one-hour period preceding the close of the principal trading session on such
Relevant Exchange; or 
  

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 (5) a breakdown or failure in the price and trade reporting systems of the primary market of any
Relevant Exchange as a result of which the reported trading prices for stocks then constituting 20% or more of the level of the related Underlying Index (or the underlying index related to such Successor Basket Index Fund) at any time during the
one-hour period preceding the close of the principal trading session on such Relevant Exchange are materially inaccurate; or 
 (6) the
occurrence or existence of a suspension, absence or material limitation of trading on any major securities exchange for trading in futures or options contracts related to the Underlying Index (or the underlying index related to such Successor Basket
Index Fund) or shares of such Basket Index Fund (or such Successor Basket Index Fund or such other security) at any time during the one-hour period preceding the close of the principal trading session on such exchange; or 
 (7) a decision to permanently discontinue trading in the relevant futures or options contracts; 
 in each case, as determined by the Calculation Agent in its sole discretion. 
 For the purpose of determining whether a Market Disruption Event exists at any time, if trading in a security included in an Underlying Index (or the
underlying index related to a Successor Basket Index Fund) is materially suspended or materially limited at that time, then the relevant percentage contribution of that security to the level of such Underlying Index (or the underlying index related
to such Successor Basket Index Fund) shall be based on a comparison of: 
  

	 	•	 	 the portion of the level of such Underlying Index (or the underlying index related to such Successor Basket Index Fund) attributable to that security relative to

  

	 	•	 	 the overall level of such Underlying Index (or the underlying index related to such Successor Basket Index Fund) 

 in each case immediately before that suspension or limitation. 
 For purposes of determining whether a Market Disruption Event has occurred: 
 (1) a limitation on the hours
or number of days of trading will not constitute a Market Disruption Event if it results from an announced change in the regular business hours of the Relevant Exchange or market; 
 (2) limitations pursuant to the rules of any Relevant Exchange similar to NYSE Rule 80B (or any applicable rule or regulation enacted or promulgated by
any other self-regulatory organization or any government agency of scope similar to NYSE Rule 80B as determined by the Calculation Agent in its sole discretion) on trading during significant market fluctuations will constitute a suspension, absence
or material limitation of trading; 
  

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 (3) a suspension of trading in futures or options contracts on an Underlying Index (or the underlying
index related to a Successor Basket Index Fund) or shares of a Basket Index Fund (or such Successor Basket Index Fund or such other security) by the primary securities market trading in such contracts by reason of: 
  

	 	•	 	 a price change exceeding limits set by such exchange or market, 

  

	 	•	 	 an imbalance of orders relating to such contracts, or 

  

	 	•	 	 a disparity in bid and ask quotes relating to such contracts 

 will, in each such case, constitute a suspension, absence or material limitation of trading in futures or options contracts related to such Underlying Index (or the underlying index related to such Successor Basket
Index Fund) or the shares of such Basket Index Fund (or such Successor Basket Index Fund or such other security); and 
 (4) a
“suspension, absence or material limitation of trading” on any Relevant Exchange or on the primary market on which futures or options contracts related to such Underlying Index (or the underlying index related to such Successor Basket
Index Fund) or the shares of such Basket Index Fund (or such Successor Basket Index Fund or such other security) are traded will not include any time when such market is itself closed for trading under ordinary circumstances. 
 “Maturity Date” shall mean June 5, 2010, unless that day is not a Business Day, in which case the amount equal to the Payment at
Maturity that would otherwise be due on the scheduled Maturity Date will instead be due on the next succeeding Business Day following such scheduled Maturity Date, with the same effect as if paid on the scheduled Maturity Date; provided that if due
to a non-Trading Day or a Market Disruption Event, the Valuation Date is postponed so that it falls less than three Business Days prior to the scheduled Maturity Date, the Maturity Date will be the third Business Day following the Valuation Date, as
postponed. 
 “NYSE” shall mean The New York Stock Exchange, Inc. 
 “Participation Rate” shall equal 110.00%. 
 “Payment at Maturity”, as calculated by the Calculation Agent for each $1,000 principal amount Security, shall equal: 
  

	 	•	 	 If the Basket Return is positive, $1,000 + [$1,000 × (Basket Return × Participation Rate)]. 

  

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	 	•	 	 If the Basket Return is equal to or less than zero, and the absolute value of the Basket Return is less than or equal to the Buffer Amount, $1,000.

  

	 	•	 	 If the Basket Return is negative and the absolute value of the Basket Return is greater than the Buffer Amount, $1,000 + [$1,000 × (Basket Return + Buffer
Amount)]. 

 “Place of Payment” shall mean the place or places where the Payment at Maturity on the
Securities is payable. 
 “price” shall mean, as to one share of any Basket Index Fund (or one unit of any other security
for which a Price must be determined) on any Trading Day: 
  

	 	•	 	 if such Basket Index Fund (or such other security) is listed or admitted to trading on a national securities exchange, the highest intraday bid price on such day on
the principal United States securities exchange registered under the Exchange Act, on which such Basket Index Fund (or any such other security) is listed or admitted to trading; 

  

	 	•	 	 if such Basket Index Fund (or such other security) is not listed or admitted to trading on any national securities exchange but is included in the OTC Bulletin
Board, the highest reported bid price reported on the OTC Bulletin Board on such day; or 

  

	 	•	 	 if a bid price is not available pursuant to the preceding bullet points, the Calculation Agent’s good faith estimate of such bid price, in its sole discretion.

 “Pricing Date” shall mean June 2, 2008. 
 “Relevant Exchange” shall mean, as to any Basket Index Fund, the primary exchange quotation system (which includes bulletin board
services) or other market of trading for the shares of such Basket Index Fund (or any Successor Basket Index Fund) or any security (or any combination thereof) then included in the related Underlying Index (or the underlying index related to a
Successor Basket Index Fund). 
 “Securities” shall have the meaning set forth on the reverse of this Security. 

“Share Adjustment Factor” shall, for each Basket Index Fund, initially equal 1.0, subject to adjustment under certain circumstances
as described under “Anti-dilution Adjustments” below. 
 “Successor Basket Index Fund” shall have the meaning
specified under the heading below “Alternative Calculation of Closing Price.” 
 “Trading Day” shall mean a day,
as determined by the Calculation Agent, on which trading is generally conducted on the NYSE, the American Stock Exchange, the Nasdaq Global Select Market, the Nasdaq Global Market, the Chicago Mercantile Exchange, the Chicago Board Options Exchange
and the over-the-counter market for equity securities in the United States. 
  

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 “Trustee” shall have the meaning set forth on the reverse of this Security. 

“Underlying Index” shall mean with respect to each Basket Index Fund, the index underlying that Basket Index Fund. 
 “Valuation Date” shall mean June 2, 2010; provided, however, that if the Valuation Date is not a Trading Day or if there is a
Market Disruption Event on such day, with respect to a Basket Index Fund, the Calculation Agent will: 
  

	 	•	 	 with respect to each Basket Index Fund for which such day is a Trading Day and for which a Market Disruption Event has not occurred, determine the
Closing Price of such Basket Index Fund for use in calculating the Basket Index Fund Final Share Price of such Basket Index Fund by reference to the Closing Price of such Basket Index Fund on that Trading Day; and 

  

	 	•	 	 with respect to each Basket Index Fund for which such day is not a Trading Day or for which a Market Disruption Event has occurred, determine the
Basket Index Fund Final Share Price of the Basket Index Fund by reference to the Closing Price of the Basket Index Fund on the next Trading Day for the Basket Index Fund on which there is not a Market Disruption Event; provided, however, if a
Market Disruption Event with respect to the Basket Index Fund occurs on each of the eight Trading Days following the originally scheduled Valuation Date, then the Calculation Agent shall determine the Basket Index Fund Final Share Price of the
Basket Index Fund based upon its good faith estimate of the price of such Basket Index Fund as of the close of trading on that eighth Trading Day, in its sole discretion. 

 All terms used but not defined in this Security are used herein as defined in the Calculation Agency Agreement or the Indenture. 
 Calculation Agent 
 The Calculation Agent will
determine, among other things, the Basket Ending Level (including each Basket Index Fund Return, the Basket Index Fund Final Share Price for each Basket Index Fund and the Basket Index Fund Initial Share Price for each Basket Index Fund), the Basket
Return, the Closing Price, as applicable, of one share of each Basket Index Fund with respect to any Trading Day for the purposes of determining the applicable Share Adjustment Factor and anti-dilution adjustments, if any, and the Payment at
Maturity on the Securities. The Calculation Agent will also be responsible for determining, among other things, whether a Market Disruption Event has occurred, which exchange traded fund will be substituted for a Basket Index Fund (or Successor
Basket Index Fund, if applicable) if a Basket Index Fund (or Successor Basket Index Fund, if applicable) is de-listed, liquidated or otherwise terminated, whether an Underlying Index (or the underlying index related to a Successor Basket Index Fund)
has been changed in a 

  

 10 

 
material respect, and whether a Basket Index Fund (or Successor Basket Index Fund, if applicable) has been so modified that such Basket Index Fund (or
Successor Basket Index Fund, if applicable) does not, in the opinion of the Calculation Agent, fairly represent the price of such Basket Index Fund (or Successor Basket Index Fund, if applicable) in the absence of such modifications. All
calculations, determinations and adjustments made by the Calculation Agent will be at the sole discretion of the Calculation Agent and will, in the absence of manifest error, be conclusive for all purposes and binding on Holders and on the Company.
The Company may appoint a different Calculation Agent from time to time after the date of the original issue of the Securities without the Holders’ consent and without notifying Holders. 
 Anti-Dilution Adjustments 
 Share Splits and
Reverse Share Splits 
 If the shares of any Basket Index Fund are subject to a share split or reverse share split, then once such split
has become effective, the applicable Share Adjustment Factor will be adjusted so that it equals the product of: 
  

	 	•	 	 the Share Adjustment Factor before such adjustment, and 

  

	 	•	 	 the number of shares that a holder of one share of such Basket Index Fund before the effective date of the share split or reverse share split would have owned or
been entitled to receive immediately following the applicable effective date. 

 Share Dividends or Distributions 

 If a Basket Index Fund is subject to (i) a share dividend, i.e., an issuance of additional shares of such Basket Index Fund
that is given ratably to all or substantially all holders of shares of such Basket Index Fund or (ii) a distribution of shares of such Basket Index Fund as a result of the triggering of any provision of the corporate charter of such Basket
Index Fund, then, once the dividend or distribution has become effective and the shares of such Basket Index Fund are trading ex-dividend, the Share Adjustment Factor will be adjusted so that it equals the Share Adjustment Factor before such
adjustment plus the product of: 
  

	 	•	 	 the Share Adjustment Factor before such adjustment, and 

  

	 	•	 	 the number of additional shares issued in the share dividend or distribution with respect to one share of such Basket Index Fund. 

 Non-cash Distributions 
 If a Basket
Index Fund distributes shares of capital stock, evidences of indebtedness or other assets or property of such Basket Index Fund to all or substantially all 

  

 11 

 
holders of shares of such Basket Index Fund (other than (i) share dividends or distributions referred to under “— Share Dividends or
Distributions” above and (ii) cash dividends referred to under “— Cash Dividends or Distributions” below), then, once the distribution has become effective and the shares of such Basket Index Fund are trading ex-dividend,
the Share Adjustment Factor will be adjusted so that it equals the product of: 
  

	 	•	 	 the Share Adjustment Factor before such adjustment, and 

  

	 	•	 	 a fraction whose numerator is the Current Market Price of one share of such Basket Index Fund and whose denominator is the amount by which such Current Market Price
exceeds the Fair Market Value of such distribution. 

 The “Current Market Price” of any Basket Index Fund means
the arithmetic average of the Closing Prices of one share of such Basket Index Fund for the ten Trading Days prior to the Trading Day immediately preceding the ex-dividend date of the distribution requiring an adjustment to the Share Adjustment
Factor. 
 The “ex-dividend date” is, with respect to a dividend or distribution on a Basket Index Fund, the first Trading Day on
which transactions in the shares of such Basket Index Fund trade on the Relevant Exchange without the right to receive that dividend or distribution. 
 The “Fair Market Value” of any such distribution is the value of such distribution on the ex-dividend date for such distribution, as determined by the Calculation Agent. If such distribution consists of
property traded on the ex-dividend date on a U.S. national securities exchange, the Fair Market Value will equal the Closing Price of such distributed property on such ex-dividend date. 
 Cash Dividends or Distributions 
 If
the issuer of any shares of a Basket Index Fund pays dividends or makes other distributions consisting exclusively of cash to all or substantially all holders of shares of such Basket Index Fund during any fiscal quarter during the term of the
Securities, in an aggregate amount that, together with other such dividends or distributions made during such quarterly fiscal period, exceeds the Dividend Threshold, then, once the dividend or distribution has become effective and the shares of
such Basket Index Fund are trading ex-dividend, the Share Adjustment Factor will be adjusted so that it equals the product of: 
  

	 	•	 	 the Share Adjustment Factor before such adjustment, and 

  

	 	•	 	 a fraction whose numerator is the Current Market Price of one share of such Basket Index Fund and whose denominator is the amount by which such Current Market Price
exceeds the amount in cash per share such Basket Index Fund distributes to holders of shares of such Basket Index Fund in excess of the Dividend Threshold. 

  

 12 

 “Dividend Threshold” shall mean, with respect to a Basket Index Fund, the amount of any cash
dividend or cash distribution distributed per share of the Basket Index Fund that exceeds the immediately preceding cash dividend or other cash distribution, if any, per share of such Basket Index Fund by more than 10% of the Closing Price of such
Basket Index Fund on the Trading Day immediately preceding the ex-dividend date. 
 The Calculation Agent will provide information as to any
adjustments to any Share Adjustment Factor upon written request by any Holder. 
 Alternative Calculation of Closing Price 
 If a Basket Index Fund (or a Successor Basket Index Fund (as defined below) is de-listed from the Relevant Exchange, liquidated or otherwise terminated,
the Calculation Agent will substitute an exchange traded fund that the Calculation Agent determines, in its sole discretion, is comparable to the discontinued Basket Index Fund (or such successor basket index fund) (such index fund being referred to
herein as a “Successor Basket Index Fund”). If a Basket Index Fund (or a Successor Basket Index Fund) is de-listed, liquidated or otherwise terminated and the Calculation Agent determines that no Successor Basket Index Fund is available,
then the Calculation Agent will, in its sole discretion, calculate the appropriate Closing Price of the shares of such Basket Index Fund (or a Successor Basket Index Fund) by a computation methodology that the Calculation Agent determines will as
closely as reasonably possible replicate such Basket Index Fund (or a Successor Basket Index Fund). If a Successor Basket Index Fund is selected or the Calculation Agent calculates a Closing Price by a computation methodology that the Calculation
Agent determines will as closely as reasonably possible replicate the Basket Index Fund (or a Successor Basket Index Fund), that Successor Basket Index Fund or Closing Price, as applicable, will be substituted for such Basket Index Fund (or such
Successor Basket Index Fund) or such Basket Index Fund’s Closing Price for all purposes of the Securities. 
 If at any time:

  

	 	•	 	 an Underlying Index (or the underlying index related to a Successor Basket Index Fund) is changed in a material respect, or 

  

	 	•	 	 a Basket Index Fund (or a Successor Basket Index Fund) in any other way is so modified that it does not, in the opinion of the Calculation Agent, fairly represent
the Closing Price of the shares of such Basket Index Fund (or such Successor Basket Index Fund) in the absence of those changes or modifications, 

 then, from and after that time, the Calculation Agent shall make such calculations and adjustments as, in the good faith judgment of the Calculation Agent, may be necessary in order to arrive at a Closing Price of an exchange traded fund
comparable to such Basket Index Fund (or such Successor Basket Index Fund) as if those changes or modifications had not been made, and the Calculation Agent shall calculate the Closing Price with reference to the shares of such Basket Index Fund (or
such Successor Basket Index Fund), as adjusted. The Calculation Agent also may determine that no adjustment is required by the modification of the method of calculation. 
  

 13 

 The Calculation Agent will provide information as to the method of calculating the Closing Price of the
shares of any Basket Index Fund (or such Successor Basket Index Fund) upon written request by any Holder. 
  

 14 

 The following abbreviations, when used in the inscription on the face of the within Security, shall be
construed as though they were written out in full according to applicable laws or regulations: 
  

							
	TEN COM -	    	as tenants in common	    	UNIF GIFT MIN ACT - _________ Custodian _________
		    		    	                          (Cust)             
     (Minor)

	TEN ENT -	    	as tenants by the entireties	    	under Uniform Gifts to Minors
	JT TEN -	    	as joint tenants with right of	    	Act	  	  

		    	Survivorship and not as tenants in common	    		  	( State)

 Additional abbreviations may also be used though not in the above list. 
                                       
                   
 FOR VALUE RECEIVED, the
undersigned hereby sells, assigns and transfers unto 
 PLEASE INSERT SOCIAL SECURITY OR 
 OTHER IDENTIFYING NUMBER OF ASSIGNEE 
  

			
	 	 	
	 	 	
	 	 	

  
  

	
	
	 

 (Name and Address of Assignee, including zip code, must be printed or typewritten.) 
  

	
	 

 the within Security, and all rights thereunder, hereby irrevocably constituting and appointing 
  

	
	 

 to transfer the said Security on the books of the Company, with full power of substitution in the premises.

 Dated: 
 __________________________________________ 
 NOTICE: The signature to this assignment must correspond with the name as it appears
upon the face of the within Security in every particular, without alteration or enlargement or any change whatever. 
 Signature(s) Guaranteed: 

____________________________ 
 THE SIGNATURE(S) SHOULD BE GUARANTEED BY AN
ELIGIBLE GUARANTOR INSTITUTION (BANKS, STOCKBROKERS, SAVINGS AND LOAN ASSOCIATIONS AND CREDIT UNIONS WITH MEMBERSHIP IN AN APPROVED MEDALLION SIGNATURE GUARANTEE PROGRAM), PURSUANT TO S.E.C. RULE 17Ad-15. 
  

 15Form of Merger Voting Agreement

 Exhibit 10.2 
 JUNE 4, 2008 
 BEAUFOUR IPSEN PHARMA, S.A.S. 
 TRIBECA ACQUISITION CORPORATION 
 AND 
 THE STOCKHOLDER NAMED HEREIN 
  
  
 VOTING AGREEMENT 
  
  
 

 

 THIS VOTING AGREEMENT (this Agreement), is entered into as of June 4, 2008, by and between the
undersigned stockholder (the Stockholder) of Tercica, Inc., a Delaware corporation (the Company), Beaufour Ipsen Pharma, a French société par actions simplifée (the Purchaser),
and Tribeca Acquisition Corporation, a newly incorporated Delaware subsidiary of the Purchaser (Merger Sub). 
 WHEREAS, in connection
with the execution of this Agreement, the Purchaser, Merger Sub and the Company are concurrently entering into an Agreement and Plan of Merger, as of the date hereof (the Merger Agreement), pursuant to which, upon the terms and subject
to the conditions thereof, Merger Sub will be merged with and into the Company, at which time the separate existence of Merger Sub shall cease and the Company will be the Surviving Corporation (the Merger); 
 WHEREAS, as of the date hereof, the Stockholder is the legal and Beneficial Owner of, and has the power to vote, the Subject Shares; and 
 WHEREAS, as a condition to the Purchaser and Merger Sub entering into the Merger Agreement, and as an inducement and consideration therefor, the Purchaser and
Merger Sub have required the Stockholder to agree to, and the Stockholder has agreed to, enter into this Agreement. 
 NOW, THEREFORE, in
consideration of the foregoing and mutual promises, representations, warranties, covenants and agreements set forth herein, the parties hereto, intending to be legally bound, hereby agree as follows: 
 1. Definitions and interpretation. 
  

	(a)	Capitalized terms used and not otherwise defined herein shall have the respective meanings assigned to them in the Merger Agreement. 

  

	(b)	Each of the following terms, when used in this Agreement, shall have the meaning set forth below: 

  

	 	(i)	Agreement has the meaning set forth in the in the preamble hereto; 

  

	 	(ii)	Beneficial Ownership by a Person of any securities means ownership by any Person who, directly or indirectly, through any contract, arrangement, understanding,
relationship or otherwise has or shares: 

  

	 	(A)	voting power which includes the power to vote, or to direct the voting of, such security; and/or 

  

	 	(B)	investment power which includes the power to dispose, or to direct the disposition of such security, and 

 shall otherwise be interpreted in accordance with the term “beneficial ownership” as defined in Rule 13d-3(a) adopted by the SEC under the
Exchange Act, as amended. The terms “Beneficially Own” and “Beneficially Owned” shall have a correlative meaning; 

	 	(iii)	Company has the meaning set forth in the preamble hereto; 

  

	 	(iv)	Governing Documents means the charter or organizational documents by which any Person (other than an individual) establishes its legal existence or which govern its
internal affairs, and shall include (A) in respect of a corporation, its certificate or articles of incorporation or association and its bylaws, (B) in respect of a partnership, its certificate of partnership and its partnership agreement
and (C) in respect of a limited liability company, its certificate of formation and operating or limited liability company agreement; 

  

	 	(v)	Lien means any security interest, pledge, mortgage, lien (statutory or other), charge, option to purchase, lease or other right to acquire any interest or any claim,
restriction, covenant, title defect, hypothecation, assignment, deposit arrangement or other encumbrance of any kind or any preference, prior or other security agreement or preferential arrangement of any kind or nature whatsoever (including any
conditional sale or other title retention agreement), excluding restrictions created by this Agreement and for transfer restrictions of general applicability under the Securities Act and under “blue sky” laws; 

  

	 	(vi)	Merger has the meaning set forth in the preamble hereto; 

  

	 	(vii)	Merger Agreement has the meaning set forth in the preamble hereto; 

  

	 	(viii)	Stockholder has the meaning set forth in the preamble hereto; 

  

	 	(ix)	Subject Shares shall mean all of the Shares and all other shares of capital stock and other equity securities of the Company, that on the date hereof, the Stockholder
is the legal and Beneficial Owner of and over which the Stockholder has the power to vote. In the event of a stock split, stock dividend or distribution, or any change in the shares of capital stock of the Company by reason thereof or by any
recapitalization, combination, reclassification, exchange of shares or similar event, the term Subject Shares shall be deemed to refer to and include such shares as well as stock dividends and distributions and any securities into
which or for which any or all of such shares of capital stock of the Company may be changed or exchanged or which are received in such transaction; 

  

	 	(x)	Transfer means, directly or indirectly, to sell, transfer (whether by merger (including by conversion into securities or other consideration), by tendering into any
tender or exchange offer, by testamentary disposition, by interspousal disposition pursuant to a domestic relations proceeding, by operation of law or otherwise), assign, pledge, encumber, hypothecate or otherwise dispose of, whether by liquidation,
dissolution, dividend, distribution or otherwise, or to enter into any contract, option or other arrangement or understanding with respect to the voting of or sale, transfer, assignment, pledge, encumbrance, hypothecation or similar disposition.

  

	(c)	The definitions of terms herein shall apply equally to the singular and plural forms of the terms defined. 

  

 Page 3 

	(d)	Whenever the context may require, any pronoun shall include the corresponding masculine, feminine and neuter forms. 

  

	(e)	The words “include”, “includes” and “including” are not limiting and shall be deemed to be followed by the phrase “without limitation”.

  

	(f)	The word “will” shall be construed to have the same meaning and effect as the word “shall”. 

  

	(g)	Any definition of or reference to any Contract, document, instrument or other record herein shall be construed as referring to such Contract, document, instrument or other record as
from time to time amended, supplemented, restated or otherwise modified. 

  

	(h)	Any reference herein to any Person shall be construed to include such Person’s successors and permitted assigns. 

  

	(i)	The words “herein”, “hereof” and “hereunder”, and words of similar import, shall be construed to refer to this Agreement in its entirety and not to any
particular provision hereof. 

  

	(j)	Unless the context otherwise requires, all references herein to Section, shall be construed to refer to Sections of this Agreement. 

  

	(k)	The headings and captions used in this Agreement are for convenience of reference only and are not to affect the construction of, or to be taken into consideration in interpreting,
this Agreement. 

 2. Representations and warranties of the Stockholder. 
 The Stockholder hereby represents and warrants to the Purchaser and Merger Sub as follows: 
  

	(a)	Organization. To the extent that the Stockholder is not an individual, the Stockholder is duly organized, validly existing and in good standing under the laws of the
jurisdiction in which it is organized and has full power and authority necessary to enable it to own the Subject Shares and to execute and deliver this Agreement, perform the obligations hereunder and to consummate the transactions contemplated
hereby. 

  

	(b)	Authority. The execution and delivery by the Stockholder of this Agreement and the consummation by the Stockholder of the transactions contemplated hereby have been duly and
validly authorized by all necessary action and no further action on the part of the Stockholder or any other Person is required in connection therewith. No Person has any authority over, or with respect to, the Subject Shares that conflicts or
competes with, or that in any way undermines, the authority of the Stockholder to execute and deliver this Agreement and perform the obligations set out herein. The Stockholder has duly executed and delivered this Agreement and, assuming this
Agreement constitutes a valid and binding obligation of the other parties hereto, this Agreement constitutes a legal, valid and binding obligation of the Stockholder, enforceable against it in accordance with its terms, except to the extent that
such enforceability may be limited by applicable bankruptcy, insolvency, fraudulent transfer, moratorium, reorganization or other similar laws affecting the enforcement of creditors’ rights generally and by principles of equity regarding the
availability of remedies (whether in a proceeding at law or in equity). 

  

 Page 4 

	(c)	Non-contravention. The execution and delivery by the Stockholder of this Agreement does not, and the consummation of the transactions contemplated hereby and the compliance
by the Stockholder with the terms hereof will not, conflict with, or result in any violation of or default (with or without notice or lapse of time, or both) under, or give rise to a right of termination, amendment, cancellation or acceleration of
any obligation or to loss of a benefit under, or result in the creation of any Lien upon the Subject Shares under, any provision of (i) the Governing Documents of the Stockholder, (ii) any Contract to which the Stockholder is a party or by
which it is bound or (iii) any Law or Order applicable to the Stockholder, except for any of the foregoing as could not reasonably be expected to impair the Stockholder’s ability to perform its obligations under this Agreement.

  

	(d)	Consents and approvals. No consent, approval, license, Order or other authorization of, or registration with, or notice to, any Governmental Entity is required to be obtained
or made by or with respect to such Stockholder in connection with the execution, delivery and performance of this Agreement or the consummation of transactions contemplated hereby except for: 

  

	 	(i)	approval of this Agreement by the Company for the purposes of Section 203 of the DGCL; and 

  

	 	(ii)	filings with the SEC of such reports under the Exchange Act as may be required in connection with this Agreement. 

  

	(e)	Ownership. As of the date of this Agreement, the Stockholder is the record and Beneficial Owner of the Subject Shares set forth on the signature page to this Agreement and
has the voting power and power of disposition with respect to the Subject Shares. Except as provided for in this Agreement: 

  

	 	(i)	the Stockholder owns the Subject Shares free and clear of all Liens; and 

  

	 	(ii)	none of the Subject Shares are subject to any voting agreement, voting trust or any other similar arrangement or restriction with respect to the voting of the Subject Shares.

  

	(f)	Other securities. The Subject Shares set forth on the signature page to this Agreement constitute all of the securities of the Company owned of record or Beneficially Owned
by the Stockholder as of the date of this Agreement. As of the date of this Agreement, the Stockholder does not, and its Affiliates do not, own or hold any voting rights with respect to any other securities of the Company. 

 

	(g)	Proxies. Any and all proxies heretofore given in respect of such Stockholder’s Subject Shares are revocable upon notice by such Stockholder, all such proxies have been
revoked prior to the date hereof and the proxy contained in this Agreement is the only proxy in effect relating to the matters set forth in Section 3 with respect to the Subject Shares as of the date of this Agreement. 

 

 Page 5 

	(h)	Absence of litigation. There is no Proceeding pending or, to the knowledge of the Stockholder, threatened against or affecting the Stockholder, or any of its Affiliates,
before or by any Governmental Entity that could reasonably be expected to impair the ability of the Stockholder to perform its obligations hereunder or to consummate the transactions contemplated hereby on a timely basis. 

3. Voting agreement 
  

	(a)	The Stockholder hereby covenants and unconditionally agrees that, until the termination of this Agreement in accordance with its terms: 

  

	 	(i)	at the Company Stockholders’ Meeting or any other meeting of the stockholders of the Company, including any adjournment or postponement thereof, however called, and in any
action by written consent of the stockholders of the Company with respect to any of the following, the Stockholder will, if a meeting is held, appear at the meeting, in person or by proxy, or otherwise cause its Subject Shares to be counted as
present thereat for purposes of establishing a quorum and will: 

  

	 	(A)	vote or consent to, or cause to be voted or consented to, all of its Subject Shares in favor of the Merger, including the adoption of the Merger Agreement, and all actions and
transactions contemplated thereby or in furtherance thereof, including, upon the request of the Purchaser, any adjournment or postponement of the Company Stockholders’ Meeting or any other meeting of the stockholders of the Company, however
called; and 

  

	 	(B)	vote (or cause to be voted) all of its Subject Shares against, and not provide consents to: 

  

	 	(I)	any and all Takeover Proposals (except by a member of the Purchaser Group) and Alternative Acquisition Agreements or any proposal or nomination made by a Person (including the
Stockholder) who is, or whose Affiliate is, making, or has publicly communicated an intention to make, a Takeover Proposal or to oppose the approval of the Merger or adoption of the Merger Agreement; or 

  

	 	(II)	any other proposal, action, transaction or agreement that is submitted to the stockholders of the Company for approval and that would reasonably be expected to (x) materially
and adversely delay, postpone, impede, affect or frustrate, (y) prevent or nullify, or (z) be in opposition to or in competition with, the Merger Agreement or any of the transactions contemplated thereunder including:

  

	 	(aa)	any extraordinary corporate transaction, such as a merger, consolidation or other business combination involving the Company; 

  

 Page 6 

	 	(bb)	a sale, lease or transfer of a material amount of assets of the Company or any reorganization, recapitalization or liquidation of the Company; 

  

	 	(cc)	an election of new members to the Company Board other than nominees to Company Board in office on the date of this Agreement; 

  

	 	(dd)	any change in the present capitalization or dividend policy of the Company or any amendment or other change to the Company’s Governing Documents, except if approved by the
Purchaser in accordance with the Merger Agreement. 

  

	 	(ii)	except as permitted under Section 4(a), at all times to retain the right to vote the Subject Shares on any matters that are at any time, or from time to time, presented for
consideration to the Company’s stockholders generally and without any other limitation on those matters other than as set forth in this Section 3(a); and 

  

	 	(iii)	not to engage in any transaction with respect to any Subject Shares with the primary purpose of depriving the Purchaser and Merger Sub of the intended benefits of this Agreement.

  

	(b)	For the avoidance of doubt, the Stockholder agrees that the obligations of the Stockholder hereunder shall not be affected by: 

  

	 	(i)	any Recommendation Change, it being understood that the delivery by the Company of a Notice of Recommendation Change pursuant to Section 6.2 of the Merger Agreement shall not,
in and of itself, constitute a Recommendation Change; or 

  

	 	(ii)	any breach by the Company of any of its representations, warranties, agreements or covenants set forth in the Merger Agreement. 

 4. Covenants of the Stockholder 
 The Stockholder hereby
covenants and unconditionally agrees as follows: 
  

	(a)	Transfer of Subject Shares. Until the termination of this Agreement in accordance with its terms, the Stockholder will not Transfer any Subject Shares, Transfer legal or
Beneficial Ownership thereof or any other interest therein; provided that Stockholder may Transfer Subject Shares (A) if Stockholder is an individual (1) up to 10% of the Subject Shares to any member of Stockholder’s immediate
family, or to a trust for the benefit of Stockholder or any member of Stockholder’s immediate family, or (2) upon the death of Stockholder, or (B) if Stockholder is a partnership or limited liability company, to one or more partners
or members of Stockholder or to an affiliated corporation under common control with Stockholder; provided that a transfer referred to in this sentence shall be permitted only if, as a precondition to such transfer, the transferee agrees in a
writing, reasonably satisfactory in form and substance to Purchaser, to be bound by all of the terms of this Agreement. Any Transfer in violation of this provision shall be null and void. 

  

 Page 7 

	(b)	Information. Except as contemplated by Section 6, the Stockholder will, upon receipt of reasonable advance notice by the Company, the Purchaser or Merger Sub, without
further consideration, promptly provide any customary information reasonably requested by the Company, the Purchaser or Merger Sub that is necessary for any regulatory application or filing made or approval sought in connection with the transactions
contemplated by his Agreement or the Merger Agreement (including filings with the SEC or any other Governmental Entity). 

  

	(c)	Subject Shares. While this Agreement is in effect the Stockholder shall notify the Purchaser promptly in writing of the number of additional Subject Shares acquired by the
Stockholder, if any, after the date hereof (such notice to be given within 3 Business Days of such acquisition). The Stockholder agrees that to the extent it acquires legal or Beneficial Ownership of any shares that fall within the definition of
Subject Shares after the date hereof, such securities shall automatically be deemed Subject Shares hereunder and shall be subject in all respect to the terms hereof to the full extent as if they were Subject Shares on the date hereof. All of the
Subject Shares as of the date hereof are detailed on the signature page hereto 

  

	(d)	Irrevocable proxy. The Stockholder hereby appoints the Purchaser and any designee of the Purchaser, and each of them individually, as the Stockholder’s attorney-in-fact
and proxy, with full power of substitution and re-substitution, during the period from the date and after the date of this Agreement and until this Agreement terminates pursuant to Section 7, to vote all of the Subject Shares or to act by
written consent in accordance with Section 3. This power of attorney and proxy is given to secure the performance of the Stockholders’ obligation set forth in Section 3. The Stockholder acknowledges that this power of attorney and
proxy (i) is coupled with an interest, (ii) constitutes, among other things, an inducement for the Purchaser and Merger Sub to enter into the Merger Agreement and (iii) is irrevocable. The power of attorney granted by the Stockholder
herein is a durable power of attorney and will survive the dissolution, bankruptcy and other incapacity of the Stockholder; and the proxy granted herein by the Stockholder is executed and is intended to be irrevocable in accordance with the
provisions of Section 212 of the DGCL. The Stockholder hereby ratifies and confirms all that such irrevocable proxy may lawfully do or cause to be done by virtue hereof and hereby revokes all other powers of attorney and proxies with respect to
the Subject Shares that it may heretofore have appointed or granted with respect to the matters set forth in Section 3. 

  

	(e)	Non-solicitation The Stockholder hereby undertakes that, while this Agreement is in effect, except as contemplated by Section 6, the Stockholder shall not, directly or
indirectly, take any action that the Company is prohibited from taking pursuant to Section 6.2 of the Merger Agreement. 

  

	(f)	Further assurances Except as contemplated by Section 6 and subject to the terms and conditions of the Merger Agreement, while this Agreement is in effect, the
Stockholder shall use all reasonable efforts to take, or cause to be taken, and to do, or cause to be done, and to assist and cooperate with the other parties in doing, all things reasonably necessary to carry out the intent and purposes of this
Agreement including executing and delivering, or causing to be executed or delivered, such additional or further consents, documents, agreements, proxies and other instruments as the Purchaser shall reasonably request for the purpose of effectively
carrying out the transactions contemplated by this Agreement. 

  

 Page 8 

	(g)	Appraisal rights The Stockholder agrees not to seek appraisal or assert any rights of dissent from the Merger that it may have under the DGCL and, to the fullest extent
permitted by Law, the Stockholder hereby waives any rights of appraisal or rights to dissent from the Merger that it may have under applicable Law. 

 5. Stockholder acknowledgements and approval 
  

	(a)	The Stockholder acknowledges that irreparable damage to the Purchaser would occur in the event that any of the provisions hereof were not performed in accordance with their specific
terms or were otherwise breached and money damages would not be an adequate remedy. Accordingly, the Stockholder agrees that prior to the termination of this Agreement in accordance with Section 7, the Purchaser and Merger Sub shall be entitled
to an injunction or injunctions to prevent breaches of this Agreement and to enforce specifically the terms and provisions of this Agreement in the Court of Chancery of the State of Delaware in addition to any other remedy to which the Purchaser or
Merger Sub may be entitled at Law or in equity, and the Stockholder hereby waives and agrees that it will not raise any defense to any action for specific performance based on the Purchaser or Merger Sub having an obligation to mitigate damages or
having an adequate remedy at Law. 

  

	(b)	The Stockholder understands and acknowledges that the Purchaser and Merger Sub are entering into the Merger Agreement in reliance upon the Stockholder’s execution and delivery
of this Agreement and the representations and warranties of the Stockholder contained herein. 

 6. Fiduciary duties 
 This Agreement shall apply to the Stockholder solely in the Stockholder’s capacity as a stockholder of the Company and the Stockholder shall vote according to the
terms of this Agreement. Nothing in this Agreement shall limit, restrict or otherwise affect, or gives rise to any liability of Stockholder by virtue of, any actions taken by Stockholder in the Stockholder’s capacity as a director or officer of
the Company, including any actions taken in connection with the exercise of rights of the Company or the Company Board (or any committee thereof) under the Merger Agreement. 
 7. Termination This Agreement and the irrevocable proxy contained herein shall terminate, and none of the Purchaser, Merger Sub or the Stockholder shall have any rights or obligations hereunder and this
Agreement shall become null and void and have no effect, upon the earliest to occur of: 
  

	(a)	the mutual consent of the Purchaser and the Stockholder; 

  

	(b)	the Effective Time; or 

  

	(c)	the date of termination of the Merger Agreement in accordance with its terms. 

  

 Page 9 

 Termination of this Agreement shall not prevent any party hereunder from seeking any remedies (at Law or equity) against
another party hereto or relieving such party from liability for such party’s willful or intentional breach of any terms of this Agreement. 
 8.
Miscellaneous 
  

	(a)	Stockholder information. The Stockholder hereby consents to the publication and disclosure in the Company Proxy Statement, statements of Beneficial Ownership filed by the
Purchaser and its Affiliates (and any other documents or communications provided by the Purchaser, Merger Sub or the Company to any Governmental Entity or to security holders of the Company) the Stockholder’s identity and beneficial ownership
(within the meaning of Rule 13d-3 of the Exchange Act) of the Subject Shares and the nature of such Stockholder’s commitments, arrangements and understandings under and relating to this Agreement; provided, however, that the
Stockholder’s Representatives shall be given a reasonable opportunity to review and comment (and such reasonable comments shall be accepted) on any such proposed disclosure. 

  

	(b)	Legends and stop transfer orders. In furtherance of this Agreement, the Stockholder hereby authorizes and instructs the Company to notify its transfer agent that this
Agreement places limits on the voting and Transfer of the Subject Shares and to instruct the transfer agent to enter a stop transfer order with respect to all of the Subject Shares and to legend the share certificates (as applicable).

  

	(c)	Control and ownership interest. Nothing contained in this Agreement shall be deemed to vest in the Purchaser or Merger Sub any direct or indirect ownership or incidence of
ownership of, or with respect to the Subject Shares. All rights, ownership and economic benefits of and relating to, and pecuniary interest in, the Subject Shares shall remain vested in and belong to the Stockholder, and the Purchaser shall not have
any authority to control, manage, direct, superintend, restrict, regulate, govern or administer the Company, or any of the policies or operations of the Company, or exercise any power or authority to direct any Stockholder in the voting of any of
the Subject Shares, except as otherwise provided in this Agreement. 

  

	(d)	Reliance by the Purchaser and Merger Sub. The Stockholder acknowledges and understands that the Purchaser and Merger Sub are entering into the Merger Agreement in reliance
upon the Stockholder’s execution and delivery of this Agreement and the representations and warranties of the Stockholder contained herein. 

  

	(e)	Rights of third parties. This Agreement is for the sole and exclusive benefit of the parties hereto and their successors and permitted assigns, and nothing herein expressed
or implied shall give, or be construe to give, to any Person, other than the parties hereto and such successors and permitted assigns, any legal or equitable right, remedies or claims under or with respect to this Agreement or any provisions hereof.
This Agreement and the rights and obligations hereunder shall not be assignable, delegable or transferable in whole or in part by any party hereto without the prior written consent of the Purchaser or Merger Sub, on the one hand, and the
Stockholder, on the other hand; provided that the Purchaser and Merger Sub may assign their respective rights hereunder to any Affiliate without the prior written consent of the Stockholder. Subject to the preceding sentence, this Agreement
will be binding upon, inure to the benefit of, and be enforceable by, the parties hereto and their respective successors and permitted assigns. Any purported assignment not permitted under this Section 8(e) shall be null and void.

  

 Page 10 

	(f)	Capacity. It is understood and agreed that to the extent the Stockholder is executing this Agreement in the capacity as a trustee of a trust, the Stockholder is executing
this Agreement only in the capacity of a trustee and as to the Subject Shares of that trust set forth on the signature page to this Agreement and in no other capacity. In addition, a Stockholder executing this Agreement in the capacity of a trustee
shall not be responsible or liable for the actions or omissions of such person’s co-trustees of such trust. 

  

	(g)	Amendment and waiver. This Agreement may only be amended, changed, supplemented, waived, or otherwise modified with a written instrument of the Purchaser and the Stockholder.
The failure of any party to exercise any of its rights under this Agreement or otherwise shall not constitute a waiver of such rights. 

  

	(h)	Fees and expenses. Each of the parties shall be responsible for its own fees and expenses, including, without limitation, the fees and expenses of its Representatives, in
connection with the entering into of this Agreement and the consummation of the transactions contemplated hereby and by the Merger Agreement; provided that the foregoing shall not be construed to modify the provisions of the Merger Agreement
pertaining to the fees and expenses applicable to the Purchaser, Merger Sub and the Company; and provided, further, that the Company shall pay the legal expenses of the Stockholder associated with the negotiation and preparation of this
Agreement. 

  

	(i)	Notices. Any notice, request, claim, demand, instruction or other communication under this Agreement shall be in writing and delivered by hand or nationally recognized
overnight courier or by facsimile to the respective parties at the following addresses (or at such other address for a party as shall be specified by like notice): 

 (i) if to the Purchaser or Merger Sub, to: 
 Beaufour Ipsen Pharma, S.A.S. 
 42, rue du Docteur Blanche 
 75016 
 France 
 Attention: Willy Mathot 
 Facsimile: + 331 44
96 11 88 
 Email: willy.mathot@ipsen.com 
 with a copy (which shall not constitute notice) to: 
 Freshfields Bruckhaus Deringer, LLP 

520 Madison Avenue, 34th Floor 
 New York,
NY 10022 
 UNITED STATES OF AMERICA 
 Attention: Matthew L. Jacobson, Esq. 
 Facsimile: +1 212 277 4001 
 Email: matthew.jacobson@freshfields.com 
  

 Page 11 

 and 
 (ii) if to Stockholder to: 
 such 
 Stockholder at the address set 
 forth on the signature page hereto 
 with a copy (which shall not constitute notice) to: 
 Cooley Godward Kronish LLP 
 Five Palo Alto Square 
 3000 El Camino Real 
 Palo Alto 
 California 94306 
 United States 

Attention: Jennifer Fonner DiNucci 
 Facsimile: +1 (650) 840 7400 
 Email: DINUCCIJF@cooley.com 
  

	(j)	Counterparts. This Agreement may be executed in any number of counterparts, including by facsimile transmission, all of which shall be one and the same agreement, and shall
become effective only when actually signed by each party hereto and each such party has received counterparts hereof signed by all of the other parties hereto. Any such counterpart may be delivered to a party by facsimile or other electronic
communication (including “.pdf”). 

  

	(k)	Severability. The provisions of this Agreement are severable and the invalidity, illegality or unenforceability of any provision will not affect the validity or
enforceability of the other provisions of this Agreement. If any provision of this Agreement, or the application of that provision to any Person or any circumstance, is invalid or unenforceable, (i) a suitable and equitable provision will be
substituted for that provision in order to carry out, so far as may be valid and enforceable, the intent and purpose of the invalid or unenforceable provision and (ii) the remainder of this Agreement and the application of that provision to
other Persons or circumstances will not be affected by such invalidity or unenforceability, nor will such invalidity or unenforceability affect the validity or enforceability of that provision, or the application of that provision, in any other
jurisdiction. 

  

	(l)	Entire Agreement. This Agreement and the irrevocable proxy contained herein and any other documents delivered by the parties in connection herewith and to the extent
referenced herein, the Merger Agreement, constitute the entire agreement between the parties with respect to the subject matter hereof and thereof and supersede all prior agreements and understandings, both written and oral, between the parties with
respect thereto. 

  

	(m)	Governing Law, submission to jurisdiction, waiver of jury trial.  

  

 Page 12 

	 	(i)	This Agreement shall be deemed to be made in and in all respects shall be interpreted, and construed in accordance with, the Laws of the State of Delaware, without giving effect to
any applicable principles of conflict of laws that would cause the Laws of another State to otherwise govern this Agreement. 

  

	 	(ii)	Each of the parties hereto irrevocably: 

  

	 	(A)	irrevocably agrees that any legal action or proceeding with respect to this Agreement and the rights and obligations arising hereunder, or for recognition and enforcement of any
judgment in respect of this Agreement and the rights and obligations arising hereunder brought by the other party hereto or its successors or assigns shall only be brought and determined in the Court of Chancery of the State of Delaware, or in the
event that court lacks jurisdiction to hear the claim, in any Delaware State court; 

  

	 	(B)	agrees that mailing of process or other papers in connection with any such action or proceeding in the manner provided in Section 8(i) or in such other manner as may be
permitted by Laws, will be valid and sufficient service thereof; 

  

	 	(C)	hereby irrevocably submits with regard to any such action or proceeding for itself and in respect of its property, generally and unconditionally, to the personal jurisdiction of the
aforesaid courts and agrees that it will not bring any action relating to this Agreement or any of the transactions contemplated by this Agreement in any court or tribunal other than the aforesaid courts; and 

  

	 	(D)	hereby irrevocably waives, and agrees not to assert, by way of motion, as a defense, counterclaim or otherwise, in any action or proceeding with respect to this Agreement and the
rights and obligations arising hereunder, or for recognition and enforcement of any judgment in respect of this Agreement and the rights and obligations arising hereunder: 

  

	 	(I)	any claim that it is not personally subject to the jurisdiction of the above named courts for any reason other than the failure to serve process in accordance with this
Section 8(m); 

  

	 	(II)	any claim that it or its property is exempt or immune from jurisdiction of any such court or from any legal process commenced in such courts (whether through service of notice,
attachment prior to judgment, attachment in aid of execution of judgment, execution of judgment or otherwise); and 

  

	 	(III)	to the fullest extent permitted by Law, any claim that (x) the suit, action or proceeding in such court is brought in an inconvenient forum, (y) the venue of such suit,
action or proceeding is improper or (z) this Agreement, or the subject matter hereof, may not be enforced in or by such courts. 

  

 Page 13 

	 	(iii)	Each party acknowledges and agrees that any controversy which may arise under this Agreement is likely to involve complicated and difficult issues and, therefore, each such party
irrevocably and unconditionally waives any right it may have to a trial by jury in respect of any Proceeding arising out of or relating to this Agreement or the transactions contemplated by this Agreement. Each party to this Agreement certifies and
acknowledges that (a) no Representative of any other party has represented, expressly or otherwise, that such other party would not seek to enforce the foregoing waiver in the event of a Proceeding, (b) such party understands and has
considered the implications of this waiver, (c) such party makes this waiver voluntarily, and (d) such party has been induced to enter into this Agreement by, among other things, the mutual waivers and certifications in this
Section 8(m). 

  

	(n)	Remedies. Except as otherwise provided under this Agreement, all rights, powers and remedies provided under this Agreement, or otherwise available in respect hereof at Law or
in equity, shall be cumulative and not alternative of any other remedy at Law or equity and the exercise of any such right, power or remedy shall not preclude the simultaneous or later exercise of any other such right, power or remedy by such party.

 [SIGNATURE PAGE FOLLOWS 
 REMAINDER OF PAGE INTENTIONALLY LEFT BLANK] 
  

 Page 14 

 IN WITNESS WHEREOF, the Stockholder, the Purchaser, Merger Sub and the Company have duly executed this Agreement
as of the date first written above. 
  

	
	BEAUFOUR IPSEN PHARMA, S.A.S.
	
	  

	Name:
	Title:
	
	TRIBECA ACQUISITION CORPORATION
	
	  

	Name:
	Title:

  

			
	NAME OF STOCKHOLDER	 	Number of Subject Shares
		
	                                      
              	 	                                      
  

  

			
	 By:
	 	  

	 Name:
	 	
	 Title:
	 	
	 Address:

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