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NEITHER THIS NOTE NOR THE SECURITIES INTO WHICH THIS NOTE IS CONVERTIBLE HAVE
BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES
COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER
THE SECURITIES ACT OF 1933, AS AMENDED (THE "SECURITIES ACT"), AND, ACCORDINGLY,
MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION
STATEMENT UNDER THE SECURITIES ACT OR PURSUANT TO AN AVAILABLE EXEMPTION FROM,
OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE
SECURITIES ACT AND IN ACCORDANCE WITH APPLICABLE STATE SECURITIES LAWS.

No. ___  U.S.                              Original Issue Date: March 20, 2002
Holder:
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Address:
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               SERIES 2002A 4% CONVERTIBLE NOTE DUE MARCH 1, 2003

     THIS Note is one of a duly authorized issue of Notes of ISONICS
CORPORATION, a California corporation, having a principal place of business at
5906 McIntyre Street, Golden, Colorado 80403 (the "COMPANY"), designated as its
Series 2002A 4% Convertible Notes, due March 1, 2003 (the "NOTES"), in an
aggregate principal amount of up to One Million and 00/100 Dollars
($1,000,000.00). This Note is acquired by the Holder (as defined herein)
pursuant to the terms of that certain Financing Agreement dated as of the
Original Issue Date (as defined herein), between the Company and the Holder, as
amended, modified or supplemented from time to time in accordance with its terms
("FINANCING AGREEMENT").

     FOR VALUE RECEIVED, the Company promises to pay to the Holder or registered
assigns, the principal sum of ___________________ and 00/100 Dollars
($___________.00), on or before March 1, 2003 (the "MATURITY DATE") and to pay
interest to the Holder on the principal sum at the rate of 4% per annum, which
interest shall be due and payable on the earlier of the Conversion Date (with
respect to the principal amount converted) or the Maturity Date. Interest shall
accrue daily commencing on the Original Issue Date (as defined in Section 6)
until payment in full of the principal sum, together with all accrued and unpaid
interest and other amounts which may become due hereunder, has been made.
Interest shall be calculated on the basis of a 360-day year and for the actual
number of days elapsed. Interest hereunder will be paid to the person in whose
name this Note (or one or more predecessor Notes) is registered on the records
of the Company regarding registration and transfers of the Notes (the "NOTE
REGISTER"). All overdue, accrued and unpaid interest and other amounts due
hereunder shall bear interest at the rate of 18% per annum from the day such
interest is due hereunder through and including the date of payment. The
principal of, and interest on, this Note are payable in such coin or currency of
the United States of America as at the time of payment is legal tender for
payment of public and private debts, at the address of the Holder last appearing
on the Note Register, except that the Company may, at the Company's option and
at any time, pay the principal amount due (but not the interest due) in shares
of the Company's Common Stock (as defined in Section 6) calculated based upon
the Conversion Price (as defined below). The Company shall provide the

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Holder notice of its intention to pay amounts hereunder in cash or shares not
less than five (5) Trading Days (as defined in Section 6) prior to the Maturity
Date. Except as otherwise provided herein, if at any time the Company pays less
than the total amount of interest then accrued on account of the Note, such
payment shall be distributed ratably among the Holders based upon the aggregate
principal amount of Notes held by each Holder.

     Notwithstanding anything to the contrary contained herein, the Company may
not prepay any portion of this Note by issuing shares of its Common Stock unless
(i) upon issuance such shares will be legally and validly issued, fully-paid,
and non-assessable; and (ii) such shares are registered for resale pursuant to
an effective Registration Statement (as defined in Section 6) and (iii) such
shares are listed or quoted for trading on an "Authorized Market" (as defined in
Section 6). Notwithstanding anything to the contrary contained herein, the
Company may not prepay any portion of this Note by issuing shares of its Common
Stock if the issuance of such shares would result in a violation of Section
4(a)(ii).

     This Note is subject to the following additional provisions:

     SECTION 1. The Notes are issuable in denominations of Fifty Thousand
Dollars ($50,000.00). The Notes are exchangeable for an equal aggregate
principal amount of Notes of different authorized denominations, as requested by
the Holder surrendering the same but shall not be issuable in denominations of
less than integral multiples of Fifty Thousand Dollars ($50,000) unless such
amount represents the full principal balance of Notes outstanding to such
Holder. No service charge will be made for such registration of transfer or
exchange.

     SECTION 2.

          (a)  This Note may not be sold, transferred, assigned, hypothecated or
divided into two or more Notes of smaller denominations, nor may any Underlying
Shares be transferred, sold, assigned or hypothecated except in accordance with
this Section. The Holder, by acceptance hereof, agrees to give written notice to
the Company before transferring this Note or transferring any Underlying Shares;
such notice will describe briefly the any proposed transfer and will give the
Company the name, address, and tax identification number of the proposed
transferee, and will further provide the Company with an opinion of the Holder's
counsel that such transfer can be accomplished in accordance with federal and
applicable state securities laws (unless such transaction is permitted by the
plan of distribution in an effective Registration Statement). Promptly upon
receiving such written notice, the Company shall present copies thereof to the
Company's counsel.

     (i) If in the opinion of such counsel the proposed transfer may be effected
     without registration or qualification (under any federal or state
     securities laws), the Company, as promptly as practicable, shall notify the
     Holder of such opinion, whereupon the Holder shall be entitled to transfer
     this Note or to dispose of Underlying Shares received upon the previous
     conversion of this Note, all in accordance with the terms of the notice
     delivered by the Holder to the Company; provided that an appropriate legend
     may be endorsed on this Note or the certificates for such Underlying Shares
     respecting restrictions upon transfer thereof necessary or advisable in the
     opinion of counsel and satisfactory to the Company to prevent further
     transfers which would be in violation of Section 5 of the Securities Act
     and applicable state securities laws; and provided further that the
     prospective transferee or purchaser shall execute such documents and make
     such representations, warranties, and agreements as may be required solely
     to comply with the

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     exemptions relied upon by the Company for the transfer or disposition of
     the Note or Underlying Shares.

     (ii) If in the opinion of the counsel referred to in this Section 2, the
     proposed transfer or disposition of this Note or such Underlying Shares
     described in the written notice given pursuant to this Section 2 may not be
     effected without registration or qualification of this Note or such
     Underlying Shares the Company shall promptly give written notice thereof to
     the Holder, and the Holder will limit its activities in respect to such as,
     in the opinion of such counsel, are permitted by law.

          (b)  Prior to transfer of this Note in compliance with this Section 2,
the Company and any agent of the Company may treat the person in whose name this
Note is duly registered on the Note Register as the owner hereof for the purpose
of receiving payment as herein provided and for all other purposes, whether or
not this Note is overdue, and neither the Company nor any such agent shall be
affected by notice to the contrary.

     SECTION 3. EVENTS OF DEFAULT.

          "EVENT OF DEFAULT" wherever used herein, means any one of the
following events (whatever the reason and whether it shall be voluntary or
involuntary or effected by operation of law or pursuant to any judgment, decree
or order of any court, or any order, rule or regulation of any administrative or
governmental body):

               (i)  any default in the payment of the principal of, interest on
     or liquidated damages, or other obligations on conversion in respect of,
     this Note, free of any claim of subordination, as and when the same shall
     become due and payable, (whether on an Interest Payment Date, Conversion
     Date or the Maturity Date or by acceleration or otherwise);

               (ii) the Company shall fail to observe or perform any other
     covenant, agreement or warranty contained in, or otherwise commit any
     breach of, this Note, the Financing Agreement or the Registration Rights
     Agreement (as defined in Section 6) and such failure or breach shall not
     have been remedied within 10 days after the date on which notice of such
     failure or breach shall have been given;

               (iii) the Company shall commence a voluntary case under the
     United States Bankruptcy Code or insolvency laws as now or hereafter in
     effect or any successor thereto (the "BANKRUPTCY CODE"); or an involuntary
     case is commenced against the Company under the Bankruptcy Code and the
     petition is not controverted within 30 days, or is not dismissed within 60
     days, after commencement of such involuntary case; or a "custodian" (as
     defined in the Bankruptcy Code) is appointed for, or takes charge of, all
     or any substantial part of the property of the Company or the Company
     commences any other proceeding under any reorganization, arrangement,
     adjustment of debt, relief of debtors, dissolution, insolvency or
     liquidation or similar law of any jurisdiction whether now or hereafter in
     effect relating to the Company or there is commenced against the Company
     any such proceeding which remains undismissed for a period of 60 days; or
     the Company is adjudicated insolvent or bankrupt; or any order of relief or
     other order approving any such case or proceeding is entered; or the
     Company suffers any appointment of any custodian or the like for it or any
     substantial part of its property which continues undischarged or unstayed
     for a period of 60 days; or the Company

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     makes a general assignment for the benefit of creditors; or the Company
     shall fail to pay, or shall state that it is unable to pay its debts
     generally as they become due;r the Company shall call a meeting of all of
     its creditors with a view to arranging a composition or adjustment of its
     debts; or the Company shall by any act or failure to act indicate its
     consent to, approval of or acquiescence in any of the foregoing; or any
     corporate or other action is taken by the Company for the purpose of
     effecting any of the foregoing;

               (iv) the Company shall default in any of its obligations under
     any mortgage, credit agreement or other facility, indenture, agreement or
     other instrument under which there may be issued, or by which there may be
     secured or evidenced any indebtedness of the Company in an amount exceeding
     two hundred thousand dollars ($200,000), whether such indebtedness now
     exists or shall hereafter be created and such default shall result in such
     indebtedness becoming or being declared due and payable prior to the date
     on which it would otherwise become due and payable;

               (v)  the Common Stock shall fail to be listed or authorized for
     quotation on an Authorized Market, or trading in an Authorized Market has
     been suspended without the Common Stock having been relisted or having such
     suspension lifted, as the case may be, within five (5) Trading Days;

               (vi) the Company shall be a party to any Change of Control
     Transaction (as defined in Section 6), shall agree to sell or dispose of
     all or in excess of 49% of its assets (based on book value calculation as
     reflected in the Company's most recent financial statements) in one or more
     transactions (whether or not such sale would constitute a Change of Control
     Transaction), or shall redeem more than a DE MINIMIS number of shares of
     Common Stock or other equity securities of the Company (other than
     redemptions of Underlying Shares);

               (vii) an Event (as hereinafter defined) shall not have been cured
     to the satisfaction of the Holder prior to the expiration of thirty (30)
     days from the Event Date (as hereinafter defined) relating thereto (other
     than as a result from a failure of a Registration Statement to be declared
     effective by the Commission on or prior to the Effective Date (as defined
     in the Registration Rights Agreement)); or

               (viii) the Company shall fail for any reason to deliver Free
     Trading Certificates (as defined in Section 6) to a Holder on or prior to
     the fifth (5th) Trading Day after a Conversion Date, or the Company shall
     provide notice to the Holder, including by way of public announcement, at
     any time, of its intention not to comply with requests for conversions of
     any Notes in accordance with the terms hereof.

     SECTION 4. CONVERSION.

          (a)  (i) This Note shall be convertible into shares of Common Stock
     (subject to the limitation set forth in Section 4(a)(ii)) at the option of
     the Holder in whole or in part at any time and from time to time commencing
     ninety-one (91) days after the Original Issue Date and prior to the close
     of business on the Maturity Date. The number of shares of Common Stock
     issuable upon a conversion hereunder shall be determined by dividing the
     outstanding principal amount of this Note to be converted by the Conversion
     Price, each as subject to adjustment as provided hereunder. The Holder
     shall effect

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     conversions by surrendering the Notes (or such portions thereof) to be
     converted, together with the form of conversion notice attached hereto as
     EXHIBIT A (the "CONVERSION NOTICE") to the Company. Each Conversion Notice
     shall specify the principal amount of Notes to be converted and the date on
     which such conversion is to be effected, which date may not be prior to the
     date of such Conversion Notice is deemed to have been delivered pursuant to
     Section 4(h) (the "CONVERSION DATE"). If no Conversion Date is specified in
     a Conversion Notice, the Conversion Date shall be the date that the
     Conversion Notice is deemed delivered pursuant to Section 4(h). Subject to
     Section 4(b) hereof, each Conversion Notice, once given, shall be
     irrevocable. If the Holder is converting less than all of the principal
     amount represented by the Note(s) tendered by the Holder with the
     Conversion Notice, or if a conversion hereunder cannot be effected in full
     for any reason, the Company shall honor such conversion to the extent
     permissible hereunder and shall promptly deliver to such Holder (in the
     manner and within the time set forth in Section 4(b)) a new Note for such
     principal amount as has not been converted.

               (ii) CERTAIN CONVERSION RESTRICTIONS. The Holder agrees not to
     convert Notes to the extent such conversion would result in the Holder
     beneficially owning (as determined in accordance with Section 13(d) of the
     Exchange Act and the rules thereunder) in excess of 4.999% of the then
     issued and outstanding shares of Common Stock, including shares issuable
     upon conversion of the Notes held by such Holder after application of this
     Section. The Holder shall have the sole authority and obligation to
     determine whether the restriction contained in this Section applies and to
     the extent the Holder determines that the restriction contained in this
     Section applies, the determination of which portion of the principal amount
     of such Notes is convertible shall be in the sole discretion of the Holder.
     The provisions of this Section may be waived by a Holder (but only as to
     itself and not to any other Holder) upon not less than 65 days prior notice
     to the Company. Other Holders shall be unaffected by any such waiver.

          (b)  (i) Not later than five (5) Trading Days after the Conversion
     Date, the Company will deliver to the Holder a Free Trading Certificate or
     certificates free of restrictive legends, trading restrictions or stop
     transfer orders representing the number of shares of the Common Stock being
     acquired upon the conversion of Notes, (ii) Notes in a principal amount
     equal to the principal amount of Notes not converted, and (iii) a corporate
     check in the amount of all accrued and unpaid interest, together with all
     other amounts then due and payable in accordance with the terms hereof, in
     respect of Notes tendered for conversion; PROVIDED, HOWEVER, that the
     Company shall not be obligated to issue certificates evidencing the shares
     of the Common Stock issuable upon conversion of the principal amount of
     Notes until Notes are either delivered for conversion to the Company or any
     transfer agent for the Notes or the Common Stock, or the Holder notifies
     the Company that such Note has been lost, stolen or destroyed and complies
     with Section 9 hereof (in which case the Company shall issue a replacement
     Note in like principal amount). The Company shall, upon request of the
     Holder, use its best efforts to deliver any certificate or certificates
     required to be delivered by the Company under this Section electronically
     through the Depository Trust Corporation or another established clearing
     corporation performing similar functions. If in the case of any Conversion
     Notice such Free Trading Certificate or certificates, are not delivered to
     or as directed by the applicable Holder by the fifth Trading Day after a
     Conversion Date, the Holder shall be entitled by written notice to the
     Company at any time on or before its receipt of such certificate or
     certificates thereafter, to rescind such conversion, in which event the
     Company shall immediately return the Notes tendered for conversion.

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               (ii) If the Company fails to deliver to the Holder such
     certificate or certificates pursuant to this Section prior to the third
     Trading Day after a Conversion Date, the Company shall pay to such Holder,
     in cash and as liquidated damages and not as a penalty, an amount equal to
     0.5% of the principal amount of the Note to be converted..

               (iii) Intentionally omitted.

               (iv) In the event a Holder shall elect to convert a Note or part
     thereof, the Company may not refuse conversion based on any claim that such
     Holder or any one associated or affiliated with such Holder has been
     engaged in any violation of law, or for any other reason, unless, an
     injunction from a court, or notice, restraining and or enjoining conversion
     of all or part of said Note shall have been sought and obtained and the
     Company posts a surety bond for the benefit of such Holder in the amount of
     130% of the amount of the Note, which is subject to the injunction, which
     bond shall remain in effect until the completion of litigation of the
     dispute and the proceeds of which shall be payable to such Holder to the
     extent Holder obtains judgment.

          (c)  (i) The conversion price (the "CONVERSION PRICE") in effect shall
     be $1.00, or as adjusted as hereinafter provided.

               (ii) If the Company, at any time while any Notes are outstanding,
     (a) shall pay a stock dividend or otherwise make a distribution or
     distributions on shares of its Common Stock or any other equity or equity
     equivalent securities payable in shares of the Common Stock, (b) subdivide
     outstanding shares of the Common Stock into a larger number of shares, (c)
     combine outstanding shares of the Common Stock into a smaller number of
     shares, or (d) issue by reclassification of shares of the Common Stock any
     shares of capital stock of the Company, the Initial Conversion Price shall
     be multiplied by a fraction of which the numerator shall be the number of
     shares of the Common Stock (excluding treasury shares, if any) outstanding
     before such event and of which the denominator shall be the number of
     shares of the Common Stock outstanding after such event. Any adjustment
     made pursuant to this Section 4(c)(ii) shall become effective immediately
     after the record date for the determination of stockholders entitled to
     receive such dividend or distribution and shall become effective
     immediately after the effective date in the case of a subdivision,
     combination or re-classification.

               (iii) If the Company, at any time while any Notes are
     outstanding, shall issue rights or warrants to all holders of the Common
     Stock (and not to Holders of Notes) entitling them to subscribe for or
     purchase shares of the Common Stock at a price per share less than the
     Conversion Price, the Conversion Price shall be multiplied by a fraction,
     of which

     the denominator shall be the number of shares of the Common Stock
     (excluding treasury shares, if any) outstanding on the date of issuance of
     such rights or warrants plus the number of additional shares of the Common
     Stock offered for subscription or purchase, and

     the numerator shall be the number of shares of the Common Stock (excluding
     treasury shares, if any) outstanding on the date of issuance of such rights
     or warrants plus the

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     number of shares which the aggregate offering price of the total number of
     shares so offered would purchase at the Conversion Price.

     Such adjustment shall be made whenever such rights or warrants are issued,
     and shall become effective immediately after the record date for the
     determination of stockholders entitled to receive such rights or warrants.
     However, upon the expiration of any right or warrant to purchase shares of
     the Common Stock the issuance of which resulted in an adjustment in the
     Conversion Price pursuant to this Section 4(c)(iii), if any such right or
     warrant shall expire and shall not have been exercised, the Conversion
     Price shall immediately upon such expiration be recomputed and effective
     immediately upon such expiration be increased to the price which it would
     have been (but reflecting any other adjustments in the Conversion Price
     made pursuant to the provisions of this Section 4 after the issuance of
     such rights or warrants) had the adjustment of the Conversion Price made
     upon the issuance of such rights or warrants been made on the basis of
     offering for subscription or purchase only that number of shares of the
     Common Stock actually purchased upon the exercise of such rights or
     warrants actually exercised.

               (iv) If the Company, as applicable with respect to Common Stock
     Equivalents (as defined below), at any time while this Note is outstanding,
     shall issue shares of Common Stock or rights, warrants, options or other
     securities or debt that is convertible into or exchangeable for shares of
     Common Stock ("COMMON STOCK EQUIVALENTS") entitling any Person to acquire
     shares of Common Stock at a price per share less than the Conversion Price,
     then the Conversion Price shall be multiplied by a fraction,

          the numerator of which shall be the number of shares of Common Stock
          outstanding immediately prior to the issuance of shares of Common
          Stock or such Common Stock Equivalents plus the number of shares of
          Common Stock which the offering price for such shares of Common Stock
          or Common Stock Equivalents would purchase at the Conversion Price,
          and

          the denominator of which shall be the sum of the number of shares of
          Common Stock outstanding immediately prior to such issuance plus the
          number of shares of Common Stock so issued or issuable,

     provided, that for purposes hereof, all shares of Common Stock that are
     issuable upon exercise or exchange of Common Stock Equivalents shall be
     deemed outstanding immediately after the issuance of such Common Stock
     Equivalents. Such adjustment shall be made whenever such shares of Common
     Stock or Common Stock Equivalents are issued.

               (v)  If the Company, at any time while Notes are outstanding,
     shall distribute to all holders of the Common Stock (and not to Holders of
     Notes) evidences of its indebtedness or assets or rights or warrants to
     subscribe for or purchase any security, then in each such case the Initial
     Conversion Price at which Notes shall thereafter be convertible shall be
     determined by multiplying the Initial Conversion Price in effect
     immediately prior to the record date fixed for determination of
     stockholders entitled to receive such distribution by a fraction of which

          the denominator shall be the Per Share Market Value of the Common
          Stock determined as of the record date mentioned above, and

          the numerator shall be such Per Share Market Value of the Common Stock
          on such record date less the then fair market value at such record
          date of the portion of such assets

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          or evidence of indebtedness so distributed applicable to one
          outstanding share of the Common Stock as determined by the Board of
          Directors in good faith; PROVIDED, HOWEVER, that in the event of a
          distribution exceeding ten percent (10%) of the net assets of the
          Company, such fair market value shall be determined by a nationally
          recognized or major regional investment banking firm or firm of
          independent certified public accountants of recognized standing (which
          may be the firm that regularly examines the financial statements of
          the Company) (an "APPRAISER") selected in good faith by the holders of
          a majority in interest of Notes then outstanding; and PROVIDED,
          FURTHER, that the Company, after receipt of the determination by such
          Appraiser shall have the right to select an additional Appraiser, in
          good faith, in which case the fair market value shall be equal to the
          average of the determinations by each such Appraiser.

     In either case the adjustments shall be described in a statement provided
     to the holders of Notes of the portion of assets or evidences of
     indebtedness so distributed or such subscription rights applicable to one
     share of the Common Stock. Such adjustment shall be made whenever any such
     distribution is made and shall become effective immediately after the
     record date mentioned above.

               (vi) In case of any reclassification of the Common Stock or any
     compulsory share exchange pursuant to which the Common Stock is converted
     into other securities, cash or property, the Holder of this Note shall have
     the right thereafter to, at its option, convert the then outstanding
     principal amount only into the shares of stock and other securities, cash
     and property receivable upon or deemed to be held by holders of the Common
     Stock following such reclassification or share exchange, and the Holders of
     the Notes shall be entitled upon such event to receive such amount of
     securities, cash or property as the shares of the Common Stock of the
     Company into which the then outstanding principal amount could have been
     converted immediately prior to such reclassification or share exchange
     would have been entitled. The terms of any such reclassification or share
     exchange shall include such terms so as to continue to give to the Holder
     the right to receive the securities, cash or property set forth in this
     Section 4(c)(vi) upon any conversion following such event. This provision
     shall similarly apply to successive reclassifications or share exchanges.

               (vii) If:

               A.   the Company shall declare a dividend (or any other
          distribution) on its Common Stock; or

               B.   the Company shall declare a special nonrecurring cash
          dividend on or a redemption of its Common Stock; or

               C.   the Company shall authorize the granting to all holders of
          the Common Stock rights or warrants to subscribe for or purchase any
          shares of capital stock of any class or of any rights; or

               D.   the approval of any stockholders of the Company shall be
          required in connection with any reclassification of the Common Stock
          of the Company, any consolidation or merger to which the Company is a
          party, any sale or transfer of all or substantially all of the assets
          of the Company, of any compulsory share of exchange whereby the Common
          Stock is converted into other securities, cash or property; or

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               E.   the Company shall authorize the voluntary or involuntary
          dissolution, liquidation or winding up of the affairs of the Company;

     then the Company shall cause to be filed at each office or agency
     maintained for the purpose of conversion of the Notes, and shall cause to
     be mailed to the Holders of Notes at their last addresses as they shall
     appear upon the stock books of the Company, at least 30 calendar days prior
     to the applicable record or effective date hereinafter specified, a notice
     stating (x) the date on which a record is to be taken for the purpose of
     such dividend, distribution, redemption, rights or warrants, or if a record
     is not to be taken, the date as of which the holders of the Common Stock of
     record to be entitled to such dividend, distributions, redemption, rights
     or warrants are to be determined or (y) the date on which such
     reclassification, consolidation, merger, sale, transfer or share exchange
     is expected to become effective or close, and the date as of which it is
     expected that holders of the Common Stock of record shall be entitled to
     exchange their shares of the Common Stock for securities, cash or other
     property deliverable upon such reclassification, consolidation, merger,
     sale, transfer or share exchange; PROVIDED, HOWEVER, that the failure to
     mail such notice or any defect therein or in the mailing thereof shall not
     affect the validity of the corporate action required to be specified in
     such notice. Holders are entitled to convert Notes during the 30-day period
     commencing the date of such notice to the effective date of the event
     triggering such notice.

               (viii) All calculations under this Section 4 shall be made to the
     nearest cent or the nearest 1/100th of a share, as the case may be.

               (ix) Whenever the Conversion Price is adjusted pursuant to
     Section 4(c)(i) - (v), the Company shall promptly mail to each Holder of
     Notes, a notice setting forth the Initial Conversion Price after such
     adjustment and setting forth a brief statement of the facts requiring such
     adjustment.

               (x)  Notwithstanding anything to the contrary herein, in no event
     shall the Conversion Price be adjusted for (i) issuances of shares upon
     exercise of any warrants, options or convertible securities outstanding as
     of the date hereof; (ii) issuances of shares upon conversion of any Notes
     or exercise of the Warrants (as defined in the Financing Agreement); or
     (iii) issuances of options (or shares upon the exercise thereof), stock
     bonuses, or shares pursuant to the Company's 1996 Stock Option Plan, 1996
     Executives Equity Incentive Plan, 1996 Equity Incentive Plan, the 1998
     Employee Stock Purchase Plan, or the Directors' Plan.

          (d)  If at any time conditions shall arise by reason of action taken
     by the Company which in the opinion of the Board of Directors are not
     adequately covered by the other provisions hereof and which might
     materially and adversely affect the rights of the Holders (different than
     or distinguished from the effect generally on rights of holders of any
     class of the Company's capital stock) or if at any time any such conditions
     are expected to arise by reason of any action contemplated by the Company,
     the Company shall mail a written notice briefly describing the action
     contemplated and the material adverse effects of such action on the rights
     of the Holders at least 30 calendar days prior to the effective date of
     such action, and an Appraiser selected by the Holders of majority in
     interest of the Notes shall give its opinion as to the adjustment, if any
     (not inconsistent with the standards established in this Section 4), of the
     Conversion Price (including, if necessary, any adjustment as to the
     securities into which Notes may thereafter be convertible) and any
     distribution which is or would be required to preserve without diluting the
     rights of the Holders; PROVIDED, HOWEVER, that the Company, after receipt
     of

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     the determination by such Appraiser, shall have the right to select an
     additional Appraiser, in good faith, in which case the adjustment shall be
     equal to the average of the adjustments recommended by each such Appraiser.
     The Board of Directors shall make the adjustment recommended forthwith upon
     the receipt of such opinion or opinions or the taking of any such action
     contemplated, as the case may be; PROVIDED, HOWEVER, that no such
     adjustment of the Conversion Price shall be made which in the opinion of
     the Appraiser(s) giving the aforesaid opinion or opinions would result in
     an increase of the Conversion Price to more than the Conversion Price then
     in effect.

          (e)  The Company covenants that it will at all times reserve and keep
     available out of its authorized and unissued shares of the Common Stock
     solely for the purpose of issuance upon conversion of the Notes and payment
     of interest on the Notes, each as herein provided, free from preemptive
     rights or any other actual contingent purchase rights of persons other than
     the Holders, not less than such number of shares of the Common Stock as
     shall (subject to any additional requirements of the Company as to
     reservation of such shares set forth in the Financing Agreement) be
     issuable (taking into account the adjustments and restrictions of Section
     4(c)) upon the conversion of the outstanding principal amount of the Notes
     and payment of interest hereunder. The Company covenants that all shares of
     the Common Stock that shall be so issuable shall, upon issue, be duly and
     validly authorized, issued and fully paid, nonassessable and, if the
     Registration Statement has been declared effective under the Securities
     Act, freely tradeable.

          (f)  Upon a conversion hereunder the Company shall not be required to
     issue stock certificates representing fractions of shares of the Common
     Stock, but may if otherwise permitted, make a cash payment in respect of
     any final fraction of a share based on the Per Share Market Value at such
     time. If the Company elects not, or is unable, to make such a cash payment,
     the holder shall be entitled to receive, in lieu of the final fraction of a
     share, one whole share of Common Stock.

          (g)  The issuance of certificates for shares of the Common Stock on
     conversion of the Notes shall be made without charge to the Holders thereof
     for any documentary stamp or similar taxes that may be payable in respect
     of the issue or delivery of such certificate, provided that the Company
     shall not be required to pay any tax that may be payable in respect of any
     transfer involved in the issuance and delivery of any such certificate upon
     conversion in a name other than that of the Holder of such Notes so
     converted and the Company shall not be required to issue or deliver such
     certificates unless or until the person or persons requesting the issuance
     thereof shall have paid to the Company the amount of such tax or shall have
     established to the satisfaction of the Company that such tax has been paid.

          (h)  Any and all notices or other communications or deliveries to be
     provided by the Holders of the Notes hereunder, including, without
     limitation, any Conversion Notice, shall be in writing and delivered
     personally, by facsimile, sent by a nationally recognized overnight courier
     service or sent by certified or registered mail, postage prepaid, addressed
     to the Company, at 5906 McIntyre Street, Golden, Colorado 80403 (facsimile
     number (303-279-7300), attention James E. Alexander, President, or such
     other address or facsimile number as the Company may specify for such
     purposes by notice to the Holders delivered in accordance with this
     Section. Any and all notices or other communications or deliveries to be
     provided by the Company hereunder shall be in

                                       10
<Page>

     writing and delivered personally, by facsimile, sent by a nationally
     recognized overnight courier service or sent by certified or registered
     mail, postage prepaid, addressed to the Holder at the facsimile telephone
     number or address of such Holder appearing on the books of the Company, or
     if no such facsimile telephone number or address appears, at the principal
     place of business of the holder. Any notice or other communication or
     deliveries hereunder shall be deemed given and effective on the earliest of
     (i) the date of transmission, if such notice or communication is delivered
     via facsimile at the facsimile telephone number specified in this Section
     prior to 5:00 p.m. (New York City time), (ii) the date after the date of
     transmission, if such notice or communication is delivered via facsimile at
     the facsimile telephone number specified in this Section later than 5:00
     p.m. (New York City time) on any date and earlier than 11:59 p.m. (New York
     City time) on such date, (iii) four days after deposit in the United States
     mails, (iv) the Business Day following the date of mailing, if send by
     nationally recognized overnight courier service, or (v) upon actual receipt
     by the party to whom such notice is required to be given.

     SECTION 5. PREPAYMENT.

          (a)  The Company shall have the right to prepay this Note and all
     accrued but unpaid interest thereon prior to the Maturity Date provided
     that, if the prepayment is accomplished in cash, the Company shall issue to
     the Holder a warrant to purchase one (1) share of Common Stock at an
     exercise price of $1.00 for each $1.00 principal amount so prepaid, and the
     warrant will be in the form attached to the Financing Agreement.

          (b)  (i) The Company shall give at least five (5) business days, but
     not more than ten (10) business days, written notice of any intention to
     prepay this Note prior to the Maturity Date to the Holder which n otice
     shall specify the "Prepayment Date.".

               (ii) With respect to any Note for which a Notice of Conversion is
     submitted to the Company prior to the Prepayment Date, the Notice of
     Conversion shall take precedence and such Note shall be converted in
     accordance with the terms hereof. Furthermore, in the event such prepayment
     is not timely made, the Notice of Prepayment shall be null and void, and
     any rights of the Company to thereafter prepay this Note shall be subject
     to the deposit of the amount to be paid in escrow, with an attorney
     designated by the Holder, not later than two business days after delivery
     of any Notice.

     SECTION 6. DEFINITIONS. For the purposes hereof, the following terms shall
have the following meanings:

          "Authorized Market" means the OTC Bulletin Board, the Nasdaq SmallCap
     Stock Market ("NASDAQ"), the American Stock Exchange, Nasdaq National
     Market or The New York Stock Exchange.

          "BUSINESS DAY" means any day except Saturday, Sunday and any day which
     shall be a legal holiday or a day on which banking institutions in the
     State of New York are authorized or required by law or other government
     action to close.

          "CHANGE OF CONTROL TRANSACTION" means the occurrence of any of (i) an
     acquisition after the date hereof by an individual or legal entity or
     "group" (as described in Rule 13d-5(b)(1) promulgated under the Exchange
     Act) of in excess of 49% of the voting securities of the Company coupled
     with a replacement of more than one-half of

                                       11
<Page>

     the members of the Company's board of directors which is not approved by
     those individuals who are members of the board of directors on the date
     hereof in one or a series of related transactions, or (ii) the merger of
     the Company with or into another entity, consolidation or sale of all or
     substantially all of the assets of the Company in one or a series of
     related transactions, unless following such transaction, the holders of the
     Company's securities continue to hold at least 40% of such securities
     following such transaction. The execution by the Company of an agreement to
     which the Company is a party or by which it is bound providing for any of
     the events set forth above in (i) or (ii) does not constitute the
     occurrence of the event until after the event in fact occurs.

          "COMMON STOCK" means the Company's common stock, no par value per
     share, and stock of any other class into which such shares may hereafter
     have been reclassified or changed.

          "FREE TRADING CERTIFICATES" SHALL MEAN CERTIFICATES REPRESENTING
     SHARES OF COMMON STOCK WHICH ARE ELIGIBLE FOR SALE PURSUANT TO AN EFFECTIVE
     REGISTRATION STATEMENT.

          "ORIGINAL ISSUE DATE" shall mean the date of the first issuance of any
     Notes regardless of the number of transfers of any Note and regardless of
     the number of instruments which may be issued to evidence such Note.

          "PERSON" means a corporation, an association, a partnership,
     organization, a business, an individual, a government or political
     subdivision thereof or a governmental agency.

          "REGISTRATION RIGHTS AGREEMENT" means the Registration Rights
     Agreement, dated March 20, 2002, between the Company and the initial
     Holders of the Notes.

          "REGISTRATION STATEMENT" means a registration statement meeting the
     requirements set forth in the Registration Rights Agreement, covering among
     other things the resale of the Underlying Shares and naming the Holder as a
     "selling stockholder" thereunder.

          "TRADING DAY" means (a) a day on which the Common Stock is traded on
     the NASDAQ, or (b) if the Common Stock is not listed on the NASDAQ, a day
     on which the Common Stock is traded in the over-the-counter market, as
     reported by the OTC Bulletin Board, or (c) if the Common Stock is not
     quoted on the OTC Bulletin Board, a day on which the Common Stock is quoted
     in the over-the-counter market as reported by the National Quotation Bureau
     Incorporated (or any similar organization or agency succeeding its
     functions of reporting prices); PROVIDED, HOWEVER, that in the event that
     the Common Stock is not listed or quoted as set forth in (a), (b) and (c)
     hereof, then Trading Day shall mean any day except Saturday, Sunday and any
     day which shall be a legal holiday or a day on which banking institutions
     in the State of New York are authorized or required by law or other
     government action to close.

          "UNDERLYING SHARES" means the number of shares of Common Stock into
     which the Notes are convertible and any shares of Common Stock issuable in
     payment of interest as provided under and in accordance with the terms
     hereof and the Financing Agreement.

                                       12
<Page>

     SECTION 7. Except as expressly provided herein, no provision of this Note
shall alter or impair the obligation of the Company, which is absolute and
unconditional, to pay the principal of, interest and liquidated damages (if any)
on, this Note at the time, place, and rate, and in the coin or currency, herein
prescribed. This Note is a direct obligation of the Company. This Note ranks
PARI PASSU with all other Notes now or hereafter issued under the terms set
forth herein.

     SECTION 8. This Note shall not entitle the Holder to any of the rights of a
stockholder of the Company, including without limitation, the right to vote, to
receive dividends and other distributions, or to receive any notice of, or to
attend, meetings of stockholders or any other proceedings of the Company, unless
and to the extent converted into shares of Common Stock in accordance with the
terms hereof. As long as there are Notes outstanding, the Company shall not and
shall cause it subsidiaries not to, without the consent of the Holders, (i)
amend its certificate of incorporation, bylaws or other charter documents so as
to adversely affect any rights of the Holders; or (ii) repay, repurchase or
otherwise acquire shares of its Common Stock or other equity securities other
than as to the Underlying Shares to the extent permitted or required under the
Related Agreements (as defined in the Purchase Agreement).

     SECTION 9. If this Note shall be mutilated, lost, stolen or destroyed, the
Company shall execute and deliver, in exchange and substitution for and upon
cancellation of a mutilated Note, or in lieu of or in substitution for a lost,
stolen or destroyed Note, a new Note for the principal amount of this Note so
mutilated, lost, stolen or destroyed but only upon receipt of evidence of such
loss, theft or destruction of such Note, and of the ownership hereof, and
indemnity, if requested, all reasonably satisfactory to the Company.

     SECTION 10. This Note shall be governed by and construed in accordance with
the laws of the State of New York. Each of the parties consents to the exclusive
jurisdiction of the federal courts whose districts encompass any part of the
City of New York or the state courts of the State of New York sitting in the
City of New York in connection with any dispute arising under this Agreement and
hereby waives, to the maximum extent permitted by law, any objection, including
any objection based on FORUM NON COVENIENS, to the bringing of any such
proceeding in such jurisdictions. To the extent determined by such court, the
Company shall reimburse the Holder for any reasonable legal fees and
disbursements incurred by the Holder in enforcement of or protection of any of
its rights under any of this Note.

     SECTION 11. Any waiver by the Company or the Holder of a breach of any
provision of this Note shall not operate as or be construed to be a waiver of
any other breach of such provision or of any breach of any other provision of
this Note. The failure of the Company or the Holder to insist upon strict
adherence to any term of this Note on one or more occasions shall not be
considered a waiver or deprive that party of the right thereafter to insist upon
strict adherence to that term or any other term of this Note. Any waiver must be
in writing.

     SECTION 12. If any provision of this Note is invalid, illegal or
unenforceable, the balance of this Note shall remain in effect, and if any
provision is inapplicable to any person or circumstance, it shall nevertheless
remain applicable to all other persons and circumstances.

                                       13
<Page>

     SECTION 13. Whenever any payment or other obligation hereunder shall be due
on a day other than a Business Day, such payment shall be made on the next
succeeding Business Day (or, if such next succeeding Business Day falls in the
next calendar month, the preceding Business Day in the appropriate calendar
month).

     SECTION 14. SECURITY. The obligation of the Company for payment of
principal, interest and all other sums hereunder, in the event of a default and
failure of the Company to perform hereunder, is secured solely by the pledge of
certain shares of the Company's Common Stock owned beneficially and of record by
the Persons specified on Schedule A hereto, (the "COLLATERAL SHARES") under the
terms and conditions of a Stock Pledge Agreement, by reference made a part of
the terms of this Note. The security interest of the Holder as to the Collateral
Shares is perfected by the delivery of such shares to Krieger & Prager, LLP, as
escrow agent pursuant to the terms of the Pledge Agreement.

                  [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]

                                       14
<Page>

     IN WITNESS WHEREOF, the Company has caused this instrument to be duly
executed by an officer duly authorized for such purpose, as of the date first
above indicated.

                                        ISONICS CORPORATION

                                        By:
                                            -----------------------------
                                            James E. Alexander, President
Attest:

By:
    ------------------------------------
    Stephen Burden, Assistant Secretary

                                       15
<Page>

                                    EXHIBIT A

                              NOTICE OF CONVERSION

(To be Executed by the Registered Holder
in order to Convert the Note)

     The undersigned hereby elects to convert Note No. [ ] into shares of Common
Stock, no par value (the "COMMON STOCK"), of ISONICS CORPORATION (the "COMPANY")
according to the conditions hereof, as of the date written below. If shares are
to be issued in the name of a person other than undersigned, the undersigned
will pay all transfer taxes payable with respect thereto and is delivering
herewith such certificates and opinions as reasonably requested by the Company
in accordance therewith, and such transfer may only be accomplished to the
extent permitted in Section 2 of this Note. No fee will be charged to the holder
for any conversion, except for such transfer taxes, if any.

Conversion calculations:
                         -------------------------
                         Date to Effect Conversion

Principal Amount of Notes to be Converted
                                          --------

Number of shares of Common Stock to be Issued

     Applicable Conversion Price

                                        Signature
                                                 -------------------------------

                                        Name
                                            ------------------------------------

                                        Address
                                               ---------------------------------

                                       16<Page>

                                                   [PROTOTYPE FOR EACH ISSUANCE]

                                 FORM OF WARRANT

THESE SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS
AMENDED, OR THE SECURITIES LAWS OF ANY STATE AND MAY NOT BE SOLD OR OFFERED FOR
SALE IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STATEMENT FOR THE SECURITIES OR
AN OPINION OF COUNSEL OR OTHER EVIDENCE ACCEPTABLE TO THE COMPANY THAT SUCH
REGISTRATION IS NOT REQUIRED.

                               ISONICS CORPORATION

                          COMMON STOCK PURCHASE WARRANT

     1.   ISSUANCE; CERTAIN DEFINITIONS. In consideration of good and valuable
consideration, the receipt of which is hereby acknowledged by ISONICS
CORPORATION, a California corporation (the "Company"), _____________ or
registered assigns (the "Holder") is hereby granted the right to purchase at
any time until 5:00 P.M., New York City time, on _____________, _______ (the
"Expiration Date"), __________________(_____)(1) fully paid and nonassessable
shares of the Company's Common Stock, no par value per share (the "Common
Stock"), at an initial exercise price per share (the "Exercise Price") of
[$1.00/1.25] per share, subject to further adjustment as set forth herein.
This Warrant is being issued pursuant to the terms of that certain Financing
Agreement, dated as of ____________,2002 (the "Agreement"), to which the
Company and Holder (or Holder's predecessor in interest) are parties.
Capitalized terms not otherwise defined herein shall have the meanings
ascribed to them in the Agreement.

     2.   EXERCISE OF WARRANTS.

          (a)  This Warrant is exercisable in whole or in part at any time and
from time to time. Such exercise shall be effectuated by submitting to the
Company (either by delivery to the Company or by facsimile transmission as
provided in Section 8 hereof) a completed and duly executed Notice of Exercise
(substantially in the form attached to this Warrant Certificate) as provided in
this paragraph. The date such Notice of Exercise is faxed to the Company shall
be the "Exercise Date," provided that the Holder of this Warrant tenders this
Warrant Certificate and full payment of the Exercise Price to the Company within
five (5)

----------
(1)  Insert Number which is equal to 20% of the Dollar Amount of the
Investment/Dollar Amount of Prepayment.
<Page>

business days thereafter. The Notice of Exercise shall be executed by the Holder
of this Warrant and shall indicate the number of shares then being purchased
pursuant to such exercise. Upon surrender of this Warrant Certificate, together
with appropriate payment of the Exercise Price for the shares of Common Stock
purchased, the Holder shall be entitled to receive a certificate or certificates
for the shares of Common Stock so purchased.

          (b)  The Exercise Price per share of Common Stock for the shares then
being exercised shall be payable in cash or by certified or official bank check
or Fed wire transfer.

          2.2  LIMITATION ON EXERCISE. Notwithstanding the provisions of this
Warrant or the Agreement, in no event (except (i) as specifically provided in
this Warrant as an exception to this provision, (ii) while there is outstanding
a tender offer for any or all of the shares of the Company's Common Stock, or
(iii) at the Holder's option, on at least sixty-five (65) days' advance written
notice from the Holder) shall the Holder be entitled to exercise this Warrant,
or shall the Company have the obligation to issue shares upon such exercise of
all or any portion of this Warrant to the extent that, after such exercise the
sum of

     (1) the number of shares of Common Stock beneficially owned by the Holder
     and its affiliates (other than shares of Common Stock which may be deemed
     beneficially owned through the ownership of the unexercised portion of the
     Warrants or other rights to purchase Common Stock or through the ownership
     of the unconverted portion of the Notes or other convertible securities),
     and

     (2) the number of shares of Common Stock issuable upon the exercise of the
     Warrants with respect to which the determination of this proviso is being
     made,

would result in beneficial ownership by the Holder and its affiliates of more
than 4.99% of the outstanding shares of Common Stock (after taking into account
the shares to be issued to the Holder upon such exercise). For purposes of the
proviso to the immediately preceding sentence, beneficial ownership shall be
determined in accordance with Section 13(d) of the Securities Exchange Act of
1934, as amended (the "1934 Act"), except as otherwise provided in clause (1) of
such sentence. The Holder, by its acceptance of this Warrant, further agrees
that if the Holder transfers or assigns any of the Warrants to a party who or
which would not be considered such an affiliate, such assignment shall be made
subject to the transferee's or assignee's specific agreement to be bound by the
provisions of this Section 2.2 as if such transferee or assignee were the
original Holder hereof.

     3.   RESERVATION OF SHARES. The Company hereby agrees that at all times
during the term of this Warrant there shall be reserved for issuance upon
exercise of this Warrant such number of shares of its Common Stock as shall be
required for issuance upon exercise of this Warrant (the "Warrant Shares").

     4.   MUTILATION OR LOSS OF WARRANT. Upon receipt by the Company of evidence
satisfactory to it of the loss, theft, destruction or mutilation of this
Warrant, and (in the case of loss, theft or destruction) receipt of reasonably
satisfactory indemnification, and (in the case of mutilation) upon surrender and
cancellation of this Warrant, the Company will execute and deliver a new Warrant
of like tenor and date and any such lost, stolen, destroyed or mutilated

                                       2
<Page>

Warrant shall thereupon become void.

     5.   RIGHTS OF THE HOLDER. The Holder shall not, by virtue hereof, be
entitled to any rights of a stockholder in the Company, either at law or equity,
and the rights of the Holder are limited to those expressed in this Warrant and
are not enforceable against the Company except to the extent set forth herein.

     6.   PROTECTION AGAINST DILUTION AND OTHER ADJUSTMENTS.

          6.1  ADJUSTMENT MECHANISM. If an adjustment of the Exercise Price is
required pursuant to Section 6.2, the Holder shall be entitled to purchase such
number of additional shares of Common Stock as will cause

     (i) the total number of shares of Common Stock Holder is entitled to
     purchase pursuant to this Warrant, multiplied by

     (ii) the adjusted Exercise Price per share, to equal

     (iii) the dollar amount of the total number of shares of Common Stock
     Holder is entitled to purchase before adjustment multiplied by the total
     Exercise Price before adjustment.

          6.2  CAPITAL ADJUSTMENTS. In case of any stock split or reverse stock
split, stock dividend, reclassification of the Common Stock, recapitalization,
merger or consolidation, or like capital adjustment affecting the Common Stock
of the Company, the provisions of this Section 6 shall be applied as if such
capital adjustment event had occurred immediately prior to the date of this
Warrant and the original Exercise Price had been fairly allocated to the stock
resulting from such capital adjustment; and in other respects the provisions of
this Section shall be applied in a fair, equitable and reasonable manner so as
to give effect, as nearly as may be, to the purposes hereof. A rights offering
to stockholders shall not be deemed a stock dividend.

          6.3  ADJUSTMENT FOR SPIN OFF. If, for any reason, prior to the
exercise of this Warrant in full, the Company spins off or otherwise divests
itself of a part of its business or operations or disposes all or a part of its
assets in a transaction (the "Spin Off") in which the Company does not receive
compensation for such business, operations or assets, but causes securities of
another entity (the "Spin Off Securities") to be issued to security holders of
the Company, then

          (a)  the Company shall cause (i) to be reserved Spin Off Securities
     equal to the number thereof which would have been issued to the Holder had
     all of the Holder's unexercised Warrants outstanding on the record date
     (the "Record Date") for determining the amount and number of Spin Off
     Securities to be issued to security holders of the Company (the
     "Outstanding Warrants") been exercised as of the close of business on the
     trading day immediately before the Record Date (the "Reserved Spin Off
     Shares"), and (ii) to be issued to the Holder on the exercise of all or any
     of the Outstanding Warrants, such amount of the Reserved Spin Off Shares
     equal to (x) the Reserved Spin Off Shares multiplied by (y) a fraction, of
     which (I) the numerator is the amount of the Outstanding Warrants then
     being exercised, and (II) the denominator is the amount of the Outstanding

                                       3
<Page>

     Warrants; and

          (b)  the Exercise Price on the Outstanding Warrants shall be adjusted
     immediately after consummation of the Spin Off by multiplying the Exercise
     Price by a fraction (if, but only if, such fraction is less than 1.0), the
     numerator of which is the average Closing Bid Price of the Common Stock for
     the five (5) trading days immediately following the fifth trading day after
     the Record Date, and the denominator of which is the average Closing Bid
     Price of the Common Stock on the five (5) trading days immediately
     preceding the Record Date; and such adjusted Exercise Price shall be deemed
     to be the Exercise Price with respect to the Outstanding Warrants after the
     Record Date.

     7.   TRANSFER TO COMPLY WITH THE SECURITIES ACT; REGISTRATION RIGHTS.

          7.1  TRANSFER. This Warrant has not been registered under the
Securities Act of 1933, as amended, (the "Act") and has been issued to the
Holder for investment and not with a view to the distribution of either the
Warrant or the Warrant Shares. Neither this Warrant nor any of the Warrant
Shares or any other security issued or issuable upon exercise of this Warrant
may be sold, transferred, pledged or hypothecated in the absence of an effective
registration statement under the Act relating to such security or an opinion of
counsel satisfactory to the Company that registration is not required under the
Act. Each certificate for the Warrant, the Warrant Shares and any other security
issued or issuable upon exercise of this Warrant shall contain a legend on the
face thereof, in form and substance satisfactory to counsel for the Company,
setting forth the restrictions on transfer contained in this Section.

          7.2  REGISTRATION RIGHTS. (a) Reference is made to the Registration
Rights Agreement. The Company's obligations under the Registration Rights
Agreement and the other terms and conditions thereof with respect to the Warrant
Shares, including, but not necessarily limited to, the Company's commitment to
file a registration statement including the Warrant Shares, to have the
registration of the Warrant Shares completed and effective, and to maintain such
registration, are incorporated herein by reference.

          (b)  In addition to the registration rights referred to in the
preceding provisions of Section 7.2(a), effective after the expiration of the
effectiveness of the Registration Statement as contemplated by the Registration
Rights Agreement, the Holder shall have piggy-back registration rights with
respect to the Warrant Shares then held by the Holder or then subject to
issuance upon exercise of this Warrant (collectively, the "Remaining Warrant
Shares"), subject to the conditions set forth below. If, at any time after the
Registration Statement has ceased to be effective, the Company participates
(whether voluntarily or by reason of an obligation to a third party) in the
registration of any shares of the Company's stock (other than a registration on
Form S-4, S-8 or successor form), the Company shall give written notice thereof
to the Holder and the Holder shall have the right, exercisable within ten (10)
business days after receipt of such notice, to demand inclusion of all or a
portion of the Holder's Remaining Warrant Shares in such registration statement.
If the Holder exercises such election, the Remaining Warrant Shares so
designated shall be included in the registration statement at no cost or expense
to the Holder (other than any costs or commissions which would be borne by the
Holder under the terms of the Registration Rights Agreement). The Holder's
rights under this Section 7 shall expire at such time as the Holder can sell all
of the Remaining Warrant Shares under Rule 144(k) without volume or other
restrictions or limit.

                                       4
<Page>

     8.   NOTICES. Any notice or other communication required or permitted
hereunder shall be in writing and shall be delivered personally, telegraphed,
telexed, sent by facsimile transmission or sent by certified, registered or
express mail, postage pre-paid. Any such notice shall be deemed given when so
delivered personally, telegraphed, telexed or sent by facsimile transmission,
or, if mailed, two days after the date of deposit in the United States mails, as
follows:

          (i)  if to the Company, to:

               Isonics Corporation
               5906 McIntyre Street
               Golden,Colorado 80403
               ATT: James E. Alexander, President
               Telephone No.: (303) 279-7900
               Telecopier No.: (303) 279-7300

          (ii) if to the Holder, to its name, address, telephone, and facsimile
               number set forth beneath its signature.

          with a copy to:

               Krieger & Prager LLP, Esqs.
               39 Broadway
               Suite 1440
               New York, NY 10006
               Attn: Samuel M. Krieger, Esq.
               Telephone No.: (212) 363-2900
               Telecopier No. (212) 363-2999

Any party may be notice given in accordance with this Section to the other
parties designate another address or person for receipt of notices hereunder.

     9.   SUPPLEMENTS AND AMENDMENTS; WHOLE AGREEMENT. This Warrant may be
amended or supplemented only by an instrument in writing signed by the parties
hereto. This Warrant contains the full understanding of the parties hereto with
respect to the subject matter hereof and thereof and there are no
representations, warranties, agreements or understandings other than expressly
contained herein and therein.

     10.  GOVERNING LAW. This Warrant shall be deemed to be a contract made
under the laws of the State of New York for contracts to be wholly performed in
such state and without giving effect to the principles thereof regarding the
conflict of laws. Each of the parties consents to the jurisdiction of the
federal courts whose districts encompass any part of the City of New York or the
state courts of the State of New York sitting in the City of New York in
connection with any dispute arising under this Warrant and hereby waives, to the
maximum extent permitted by law, any objection, including any objection based on
FORUM NON CONVENIENS, to the bringing of any such proceeding in such
jurisdictions. To the extent determined by such

                                       5
<Page>

court, the Company shall reimburse the Holder for any reasonable legal fees and
disbursements incurred by the Buyer in enforcement of or protection of any of
its rights under any of the Transaction Agreements.

     11.  JURY TRIAL WAIVER. The Company and the Holder hereby waive a trial by
jury in any action, proceeding or counterclaim brought by either of the Parties
hereto against the other in respect of any matter arising out or in connection
with this Warrant.

     12.  COUNTERPARTS. This Warrant may be executed in any number of
counterparts and each of such counterparts shall for all purposes be deemed to
be an original, and all such counterparts shall together constitute but one and
the same instrument.

     13.  DESCRIPTIVE HEADINGS. Descriptive headings of the several Sections of
this Warrant are inserted for convenience only and shall not control or affect
the meaning or construction of any of the provisions hereof.

     IN WITNESS WHEREOF, the parties hereto have executed this Warrant as of the
___ day of ________________, 2002.

                                        ISONICS CORPORATION

                                        By:
                                            ------------------------------------
                                            JAMES E. ALEXANDER, PRESIDENT

ATTEST:

John V. Sakys, Secretary

                          NOTICE OF EXERCISE OF WARRANT

     The undersigned hereby irrevocably elects to exercise the right,
represented by the Warrant Certificate dated as of ________________, ____, to
purchase ________ shares of the Common Stock, no par value, of ISONICS
CORPORATION and tenders herewith payment in accordance with Section 1 of said
Common Stock Purchase Warrant.

_    CASH: $                               =  (Exercise Price x Exercise Shares)
            ------------------------------

           Payment is being made by:
               _    enclosed check
               _    wire transfer
               _    other

     It is the intention of the Holder to comply with the provisions of Section
2.2 of the Warrant regarding certain limits on the Holder's right to exercise
thereunder. Based on the

                                       6
<Page>

analysis on the attached Worksheet Schedule, the Holder believe this exercise
complies with the provisions of said Section 2.2. Nonetheless, to the extent
that, pursuant to the exercise effected hereby, the Holder would have more
shares than permitted under said Section, this notice should be amended and
revised, ab initio, to refer to the exercise which would result in the issuance
of shares consistent with such provision. Any exercise above such amount is
hereby deemed void and revoked.

     Please deliver the stock certificate to:

Dated:

[Name of Holder]

By:

                                       7
<Page>

                          NOTICE OF EXERCISE OF WARRANT
                               WORKSHEET SCHEDULE

1.   Current Common Stock holdings of Holder and Affiliates        _____________

2.   Shares to be issued on current exercise                       _____________

3.   Other shares eligible to be acquired without restriction      _____________

4.   Total [sum of Lines 1 through 3]                              _____________

5.   Outstanding shares of Common Stock                            _____________

6.   Adjustments to Outstanding

     a.   Shares from Line 1 not included in Line 5                 ____________

     b.   Shares to be issued per Line 2                            ____________

     c.   Total Adjustments [Lines 6a and 6b]                      _____________

7.   Total Adjusted Outstanding [Lines 5 plus 6c]                  _____________

8.   Holder's Percentage [Line 4 divided by Line 7]               _____________%

[Note: Line 8 not to be above 4.99%]

                                       8

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