Document:

Orgenesis Inc. - Exhibit 4.3 - Filed by newsfilecorp.com

EXHIBIT D 
FORM OF WARRANT

THESE WARRANTS ARE NOT TRANSFERABLE 

NONE OF THE SECURITIES REPRESENTED HEREBY HAVE BEEN
REGISTERED UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE “1933
ACT”), OR ANY U.S. STATE SECURITIES LAWS, AND, UNLESS SO REGISTERED, NONE MAY BE
OFFERED OR SOLD, DIRECTLY OR INDIRECTLY, IN THE UNITED STATES OR TO U.S. PERSONS
EXCEPT IN ACCORDANCE WITH THE PROVISIONS OF REGULATION S UNDER THE 1933 ACT,
PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE 1933 ACT, OR PURSUANT
TO AN EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION
REQUIREMENTS OF THE 1933 ACT AND IN EACH CASE ONLY IN ACCORDANCE WITH APPLICABLE
SECURITIES LAWS. 

ORGENESIS INC. 
(A Nevada Corporation) 

NON-TRANSFERABLE 
WARRANT CERTIFICATE 

CERTIFICATE NO. 2018 _____

	NUMBER OF WARRANTS: ________	RIGHT TO PURCHASE
      __________Shares 

THESE NON-TRANSFERABLE WARRANTS WILL EXPIRE AND BECOME NULL AND
VOID 
AT 5:00 P.M. (PACIFIC TIME) ON THE EXPIRY DATE (AS DEFINED IN THE TERMS
AND 
CONDITIONS ATTACHED TO THIS WARRANT CERTIFICATE. 

NON-TRANSFERABLE SHARE PURCHASE WARRANTS 
TO PURCHASE COMMON
SHARES OF ORGENESIS INC. 

THE WARRANTS ARE REPRESENTED BY THIS CERTIFICATE. 

This is to certify that, for value received, ________________
(the “Holder”) has the right to purchase, upon and subject to the terms
and conditions attached hereto as Appendix “A” (the “Terms and
Conditions”) from October __, 2018 to 5:00 p.m. (Pacific Time) on the Expiry
Date (as defined in the attached Terms and Conditions), the number of fully paid
and non-assessable common shares (the “Shares”) of Orgenesis Inc. (the
“Company”) set out above, by surrendering to the Company, at its offices
at 20271 Goldenrod Lane, Germantown, MD 20876, this Warrant Certificate with a
Subscription in the form attached hereto as Appendix “B”, duly completed and
executed, and cash, bank draft, certified cheque or money order in lawful money
of the United States of America, payable to the order of the Company in an
amount equal to the purchase price per Share multiplied by the number of Shares
being purchased (the “Aggregate Purchase Price”). Subject to adjustment
thereof in the events and in the manner set forth in the Terms and Conditions,
the purchase price per Share on the exercise of each Non-Transferable Share
Purchase Warrant (“Warrant”) evidenced hereby shall be US $7.00
per Share (subject to adjustment as described in the Terms and Conditions). 

These Warrants are issued subject to the Terms and Conditions,
and the Holder may exercise the right to purchase Shares only in accordance with
the Terms and Conditions. 

Nothing contained herein or in the Terms and Conditions will
confer any right upon the Holder or any other person to subscribe for or
purchase any Shares at any time subsequent to the Expiry Date and from and after
such time, these Warrants and all rights hereunder will be void and of no value.

IN WITNESS WHEREOF the Company has caused this Warrant
Certificate to be executed. 

DATED at the City of Scottsdale, in the __________, as of the
________day of _______, _______. 

ORGENESIS INC. 

Per:       
__________________________
              
Name: Neil
Reithinger 
              
Title: Chief Financial Officer 

PLEASE NOTE THAT ALL SHARE CERTIFICATES ISSUED TO NON-U.S.
PERSONS UPON EXERCISE HEREOF MUST BE LEGENDED AS FOLLOWS: 

“THESE SECURITIES WERE ISSUED IN AN OFFSHORE TRANSACTION TO
PERSONS WHO ARE NOT U.S. PERSONS (AS DEFINED IN REGULATION S UNDER THE 1933 ACT)
PURSUANT TO REGULATION S UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS
AMENDED (THE “1933 ACT”). ACCORDINGLY, NONE OF THE SECURITIES TO WHICH THIS
CERTIFICATE RELATES HAVE BEEN REGISTERED UNDER THE 1933 ACT, OR ANY U.S. STATE
SECURITIES LAWS, AND, UNLESS SO REGISTERED, NONE MAY BE OFFERED OR SOLD IN THE
UNITED STATES OR, DIRECTLY OR INDIRECTLY, TO U.S. PERSONS EXCEPT IN ACCORDANCE
WITH THE PROVISIONS OF REGULATION S UNDER THE 1933 ACT, PURSUANT TO AN EFFECTIVE
REGISTRATION STATEMENT OR PURSUANT TO AN EXEMPTION FROM, OR IN A TRANSACTION NOT
SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE 1933 ACT AND IN EACH CASE ONLY
IN ACCORDANCE WITH APPLICABLE STATE SECURITIES LAWS. IN ADDITION, HEDGING
TRANSACTIONS INVOLVING THE SECURITIES MAY NOT BE CONDUCTED UNLESS IN ACCORDANCE
WITH THE 1933 ACT.” 

PLEASE NOTE THAT ALL SHARE CERTIFICATES ISSUED TO U.S. PERSONS
UPON EXERCISE HEREOF MUST BE LEGENDED AS FOLLOWS: 

NONE OF THE SECURITIES REPRESENTED HEREBY HAVE BEEN REGISTERED
UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE “1933 ACT”), OR
ANY U.S. STATE SECURITIES LAWS, AND, UNLESS SO REGISTERED, NONE MAY BE OFFERED
OR SOLD, DIRECTLY OR INDIRECTLY, IN THE UNITED STATES OR TO U.S. PERSONS EXCEPT
IN ACCORDANCE WITH THE PROVISIONS OF REGULATION S UNDER THE 1933 ACT, PURSUANT
TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE 1933 ACT, OR PURSUANT TO AN
EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION
REQUIREMENTS OF THE 1933 ACT AND IN EACH CASE ONLY IN ACCORDANCE WITH APPLICABLE
SECURITIES LAWS. 

2

APPENDIX “A” 

TERMS AND CONDITIONS dated as of ____________, 2018 (the “Terms
and Conditions”), attached to the Non-Transferable Share Purchase Warrants
issued by Orgenesis Inc. 

1.         
 Definitions

In these Terms and Conditions, unless there is something in the
subject matter or context inconsistent therewith: 

(a)         “Business
Day” means any day other than a Saturday, Sunday, or a day on which banking
institutions in the State of Nevada are authorized or obligated by law or
executive order to close. 

(b)         “Company”
means Orgenesis Inc., a Nevada corporation. If a successor corporation will have
become such as a result of consolidation, amalgamation or merger with or into
any other corporation or corporations, or as a result of the conveyance or
transfer of all or substantially all of the properties and estates of the
Company as an entirety to any other corporation and thereafter “Company” will
mean such successor corporation; 

(c)         “Company’s
Auditors” means an independent firm of accountants duly appointed as auditors of
the Company; 

(d)         “Exercise
Price” means US $7.00 per Share, subject to adjustment as provided in the Terms
and Conditions; 

(e)         “Expiry
Date” means the third anniversary from the date of the issuance of the Note to
the Holder; 

(f)         “herein”,
“hereby” and similar expressions refer to these Terms and Conditions as the same
may be amended or modified from time to time; and the expression “Section”
followed by a number refer to the specified Section of these Terms and
Conditions; 

(g)         “person”
means an individual, corporation, partnership, trustee or any unincorporated
organization and words importing persons have a similar meaning; 

(h)         “Holder”
or “Holders” means the holder of the Warrants and its heirs, executors,
administrators, successors, legal representatives and assigns; 

(i)         “Shares”
means the shares of common stock in the capital of the Company as constituted at
the date hereof and any shares resulting from any subdivision or consolidation
of such shares, issued upon exercise of the Warrants; 

(j)         “Trading
Day” means any day on which the Common Stock is traded on The Nasdaq Capital
Market, or, if The Nasdaq Capital Market is not the principal trading market for
the Common Stock, then on the principal securities exchange or securities market
on which the Common Stock is then traded. 

(k)         “Warrants”
means the Non-Transferable Share Purchase Warrants of the Company issued and
presently authorized and for the time being outstanding; and

(l)         “1933
Act” means the United States Securities Act of 1933. 

3

2.          
Interpretation 

The division of these Terms and Conditions into sections and
the insertion of headings are for convenience of reference only and shall not
affect the construction or interpretation thereof. Words importing the singular
number include the plural and vice versa and words importing the masculine
gender include the feminine and neuter genders. 

3.          
Applicable Law

The rights and restrictions attached to the Warrants shall be
construed in accordance with the laws of the State of Nevada. 

4.         
 Additional Issuances of Securities

The Company may at any time and from time to time do further
equity or debt financing and may issue additional shares, warrants, convertible
securities, stock options or similar rights to purchase shares of its capital
stock. 

5.          
Replacement of Lost Warrants

In case this Warrant Certificate shall become mutilated, lost,
destroyed or stolen, the Company in its discretion may issue and deliver a new
Warrant Certificate of like date and tenure as the one mutilated, lost,
destroyed or stolen, in exchange for and in place of and upon cancellation of
such mutilated Warrant Certificate, or in lieu of, and in substitution for such
lost, destroyed or stolen Warrant Certificate and the substituted Warrant
Certificate shall be entitled to all benefits hereunder and rank equally in
accordance with its terms with all other Warrants issued or to be issued by the
Company. 

The applicant for the issue of a new Warrant Certificate
pursuant hereto shall bear the cost of the issue thereof and in case of loss,
destruction or theft shall furnish to the Company evidence of ownership and of
loss, destruction or theft of the Warrant Certificate so lost, destroyed or
stolen as shall be satisfactory to the Company and its transfer agent in
accordance with its usual policies and procedures and such applicant may also be
required to furnish indemnity in the amount and form satisfactory to the Company
and its transfer agent in accordance with its usual policies and procedures, and
shall pay the reasonable charges of the Company in connection therewith. 

6.         
 Warrant Holder Not a Shareholder

The holding of a Warrant Certificate will not constitute the
Holder as a shareholder of the Company, nor entitle the Holder to any right or
interest in respect thereof except as is expressly provided in the Warrant
Certificate or these Terms and Conditions. 

7.          
Warrants Not Transferable

The Warrants and all rights attached thereto are not
transferable. 

8.           Notice
to Holders

Any notice required or permitted to be given to the Holder will
be in writing and may be given by prepaid registered post, electronic facsimile
transmission or other means of electronic communication capable of producing a
printed copy to the address of the Holder appearing on the Warrant Certificate
or to such other address as any Holder may specify by notice in writing to the
Company, and any such notice will be deemed to have been given and received by the Holder to whom it
was addressed if mailed, on the third day following the mailing thereof, if by
facsimile or other electronic communication, on successful transmission, or, if
delivered, on delivery; but if at the time of mailing or between the time of
mailing and the third Business Day thereafter there is a strike, lockout, or
other labour disturbance affecting postal service, then the notice will not be
effectively given until actually delivered. 

4

9.          
  Notice to the Company

Any notice required or permitted to be given to the Company
will be in writing and may be given by prepaid registered post, electronic
facsimile transmission or other means of electronic communication capable of
producing a printed copy to the address of the Company set forth below or such
other address as the Company may specify by notice in writing to the Holder, and
any such notice will be deemed to have been given and received by the Company to
whom it was addressed if mailed, on the third day following the mailing thereof,
if by facsimile or other electronic communication, on successful transmission,
or, if delivered, on delivery; but if at the time or mailing or between the time
of mailing and the third Business Day thereafter there is a strike, lockout, or
other labour disturbance affecting postal service, then the notice will not be
effectively given until actually delivered: 

Orgenesis Inc. 
c/o Eventus Advisory Group, LLC 
14201 N.
Hayden Road, Suite A-1 
Scottsdale, AZ 85260 
Attention: Neil Reithinger,
CFO 

10.        
Method of Exercise of Warrants 

The right to purchase Shares conferred by the Warrants may be
exercised by the Holder of such Warrant by surrendering it to the Company, with
a duly completed and executed subscription in the form attached as Appendix “B”
and cash, bank draft, certified cheque or money order payable to or to the order
of the Company for the Aggregate Purchase Price subscribed for in lawful money
of the United States of America. 

11.         Mandatory
Exercise of Warrants

If at any time from and after the date hereof, the closing
price of the Company’s Common Stock on the Nasdaq Capital Market (or other
national stock exchange or market on which the Common Stock is then listed or
quoted) equals or exceeds $20.00 per share (which amount may be adjusted for
certain capital events, such as stock splits, as described herein) for thirty
(30) consecutive Trading Days (the “Mandatory Exercise Measuring
Period”), then the Company shall have the right to require the Holder to
exercise all or any portion of this Warrant still unexercised for a cash
exercise, as designated in the Mandatory Exercise Notice on the Mandatory
Exercise Date (each as defined below) into fully paid, validly issued and
nonassessable shares of Common Stock in accordance with Section 10 hereof at the
Exercise Price as of the Mandatory Exercise Date (as defined below) (a
“Mandatory Exercise”). The Company may exercise its right to require
exercise under this Section 5 by delivering within not more than five (5)
Trading Days following the end of such Mandatory Exercise Measuring Period a
written notice thereof by electronic mail to the Holder (the “Mandatory
Exercise Notice” and the date that the Holder received such notice is
referred to as the “Mandatory Exercise Notice Date”). The Mandatory
Exercise Notice shall be irrevocable. The Mandatory Exercise Notice shall state
(I) the Trading Day on which the Mandatory Exercise shall occur, which shall be
the second (2nd) Trading Day following the Mandatory Exercise Notice Date (the
“Mandatory Exercise Date”) and (II) the aggregate number of Warrants
which the Company has elected to be subject to such Mandatory Exercise from the
Holder (the “Mandatory Exercise Amount”) pursuant to this Section 11.

5

12.         Effect
of Exercise of Warrants 

Upon surrender and payment as aforesaid, the Shares so
subscribed for shall be deemed to have been issued and such Holder shall be
deemed to have become the holder (or holders) of record of such Shares on the
date of such surrender and payment and such Shares shall be issued at the
Exercise Price in effect on the date of such surrender and payment. 

Within ten Business Days after surrender and payment as
aforesaid, the Company shall forthwith cause to be delivered to the person or
persons in whose name or names the Shares so subscribed for are to be issued as
specified in such subscription or mailed to him or them at his or their
respective addresses specified in such subscription, a certificate or
certificates for the appropriate number of Shares not exceeding those which the
Holder is entitled to purchase pursuant to the Warrant surrendered. 

13.         Subscription
for Less than Entitlement

The Holder of any Warrant may subscribe for and purchase a
number of Shares less than the number which he is entitled to purchase pursuant
to the surrendered Warrant. In the event of any purchase of a number of Shares
less than the number which can be purchase pursuant to a Warrant, the Holder,
upon exercise thereof, shall be entitled to receive a new Warrant Certificate in
respect of the balance of the Shares which he was entitled to purchase pursuant
to the surrendered Warrant Certificate and which were not then purchased. 

14.         Warrants
for Fractions of Shares

To the extent that the Holder of any Warrant is entitled to
receive on the exercise or partial exercise thereof a fraction of a Share, such
right may be exercised in respect of such fraction only in combination with
another Warrant or other Warrants which in the aggregate entitle the Holder to
receive a whole number of such Shares. 

15.         Expiration
of Warrants

After the expiration of the Expiry Period, all rights
thereunder shall wholly cease and terminate and such Warrants shall be void and
of no further force and effect. 

16.         Adjustment
of Exercise Price

The Exercise Price and the number of Common Shares deliverable
upon the exercise of the Warrants shall be subject to adjustment in the event
and in the manner following: 

(a)         If and
whenever the Shares at any time outstanding shall be subdivided into a greater
or consolidated into a lesser number of Shares, the Exercise Price shall be
decreased or increased proportionately, as the case may be, and upon any such
subdivision or consolidation, the number of Shares deliverable upon the exercise
of the Warrants shall be increased or decreased proportionately, as the case may
be; 

(b)         In
case of any capital reorganization or of any reclassification of the capital of
the Company or in case of the consolidation, merger or amalgamation of the
Company with or into any other company or of the sale of the assets of the
Company as or substantially as an entirety or of any other company, each Warrant
shall, after such capital reorganization, reclassification of capital,
consolidation, merger, amalgamation or sale, confer the right to purchase that
number of shares or other securities or property of the Company or of the
company resulting from such capital reorganization, reclassification, consolidation, merger, amalgamation or to which such sale shall
be made, as the case may be, to which the Holder of the shares deliverable at
the time of such capital reorganization, reclassification of capital,
consolidation, merger, amalgamation or sale had the Warrants been exercised,
would have been entitled on such capital reorganization, reclassification,
consolidation, merger, amalgamation or sale and in any such case, if necessary,
appropriate adjustments shall be made in the application of the provisions set
forth in Sections 13 to 20 hereof with respect to the rights and interest
thereafter of the Holders of the Warrants to the end that the provisions set
forth in Sections 13 to 20 hereof shall thereafter correspondingly be made
applicable as nearly as may reasonable be expected in relation to any shares or
other securities or property thereafter deliverable on the exercise of the
Warrants. The subdivision or consolidation of the Shares at any time outstanding
into a greater or lesser number of Shares (whether with or without par value)
shall not be deemed to be a capital reorganization or a reclassification of the
capital of the Company for the purposes of this Section 16(b). 

6

The adjustments provided for in this Section 16 pursuant to any
Warrants are cumulative .and will become effective immediately after the record
date for, or, if no record date is fixed, the effective date, of the event which
results in such adjustments. 

17.         Determination
of Adjustments

If any questions shall at any time arise with respect to the
Exercise Price or any adjustments provided for in this Warrant, such questions
shall be conclusively determined by the Company’s Auditors, from time to time,
or, if they decline to so act, any other firm of chartered accountants that the
Company may designate and who shall have access to all appropriate records and
such determination shall be binding upon the Company and the Holders. 

18.         Covenants
of the Company

The Company will reserve and there will remain unissued out of
its authorized capital a sufficient number of Shares to satisfy the rights of
purchase provided for in the Warrants should the Holders of all the Warrants
from time to time outstanding determine to exercise such rights in respect of
all Shares which they are or may be entitled to purchase pursuant thereto. 

19.        
Immunity of Shareholders, etc.

The Holder hereby waives and releases any right, cause of
action or remedy now or hereafter existing in any jurisdiction against any past,
present or future incorporator, shareholder, director or officer (as such) of
the Company for the issue of Shares pursuant to any Warrant or on any covenant,
agreement, representation or warranty by the Company herein contained. 

20.         Modification
of Terms and Conditions for Certain Purposes

From time to time the Company may, subject to the provisions of
these presents, and it shall, when so directed by these presents, modify the
terms, and conditions hereof, for any one or more of any of the following
purposes: 

(a)         making
such provisions not inconsistent herewith as may be necessary or desirable with
respect to matters or questions arising hereunder or for the purpose of
obtaining a listing or quotation of the Warrants on any stock exchange or
quotation system; 

7

(b)         adding
to or altering the provisions hereof in respect of the registration and transfer
of Warrants making provisions for the exchange of Warrants of different
denominations; and making any modification in the form of the Warrants which
does not affect the substance thereof; 

(c)         for
any other purpose not inconsistent with the terms hereof, including the
correction or recertification of any ambiguities, defective provisions, errors
or omissions herein; and 

(d)         to
evidence any successions of any corporation and the assumption of any successor
of the covenants of the Company herein and in the Warrants contained as provided
herein. 

21.         United
States Restrictions

These Warrants and the Shares issuable upon the exercise of
these Warrants have not been and will not be registered under the 1933 Act as
amended or any state securities laws. These Warrants may not be exercised in the
United States (as defined in Regulation S under the 1933 Act) unless these
Warrants and the Shares issuable upon exercise hereof have been registered under
the 1933 Act, and any applicable state securities laws or unless an exemption
from such registration is available. 

DATED as of the date first above written in these Terms and
Conditions. 

ORGENESIS INC. 

Per:     
__________________________________________
            
Name: Neil
Reithinger 
            
Title: Chief Financial Officer 

8

APPENDIX “B” 

SUBSCRIPTION FORM

(ONE NON-TRANSFERABLE SHARE PURCHASE WARRANT IS 
REQUIRED TO
SUBSCRIBE FOR EACH COMMON SHARE) 

TO:      ORGENESIS INC.

20271 Goldenrod Lane 
Germantown, MD 20876 

The undersigned, bearer of the attached Non-Transferable Share
Purchase Warrants, hereby subscribes for _____________ of shares of common stock
of Orgenesis Inc. (the “Company”) referred to in the Warrants according
to the conditions thereof and herewith makes payment of the purchase price in
full for the said number of shares at the price of U.S. $7.00 per share if
exercised on or before 5:00 p.m. (Pacific Time) on the Expiry Date (as that term
is defined in the Terms and Conditions attached to the Non-Transferable Share
Purchase Warrant). Cash, a certified cheque, bank draft or money order is
enclosed herewith for such amount. 

The undersigned hereby directs that the shares hereby
subscribed for be issued and delivered as follows: 

	Name(s) in Full 	 	Address(es) 	 	Number of Shares 
	 	 	 	 	 
	 	 	 	 	 

(Please print full names in which share certificates are to be
issued. The Share must be issued in the name of the Holder.) 

DATED this ______ day of ___________________, 20___ . (the
“Exercise Date”) 

	 	 	 
	Witness 	 	Signature 
	Please print your name and address in full 	 	  
	  	 	  
	  	 	Address
    ________________________________________
	 	 	 
	 	 	               
      ________________________________________

TERMS AND CONDITIONS 

The Warrants are issued subject to the Terms and Conditions,
which are attached to the Warrant Certificate delivered to the Holder.

9

[APPLIES TO NON-U.S. PERSONS ONLY:] 

REPRESENTATIONS AND WARRANTIES 

The undersigned represents and warrants that the undersigned is
not a “U.S. person”, as such term is defined in Regulation S as promulgated
under the United States Securities Act of 1933, as at the Exercise Date. The
undersigned represents and warrants that the representations and warranties in
the subscription agreement between the undersigned and the Company dated the
Holder are true and correct as of the date of the Exercise Date. 

LEGENDS

The certificates representing the shares acquired on the
exercise of the Warrants will bear a legend in substantially the following form:

“THESE SECURITIES WERE ISSUED IN AN OFFSHORE TRANSACTION TO A
PERSON WHO IS NOT A U.S. PERSON (AS DEFINED HEREIN) PURSUANT TO REGULATION S
UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE “1933 ACT”).
ACCORDINGLY, NONE OF THE SECURITIES TO WHICH THIS CERTIFICATE RELATES HAVE BEEN
REGISTERED UNDER THE 1933 ACT, OR ANY U.S. STATE SECURITIES LAWS, AND, UNLESS SO
REGISTERED, NONE MAY BE OFFERED OR SOLD IN THE UNITED STATES (AS DEFINED HEREIN)
OR, DIRECTLY OR INDIRECTLY, TO U.S. PERSONS EXCEPT IN ACCORDANCE WITH THE
PROVISIONS OF REGULATION S UNDER THE 1933 ACT, PURSUANT TO AN EFFECTIVE
REGISTRATION STATEMENT OR PURSUANT TO AN EXEMPTION FROM, OR IN A TRANSACTION NOT
SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE 1933 ACT AND IN EACH CASE ONLY
IN ACCORDANCE WITH APPLICABLE STATE SECURITIES LAWS. IN ADDITION, HEDGING
TRANSACTIONS INVOLVING THE SECURITIES MAY NOT BE CONDUCTED UNLESS IN ACCORDANCE
WITH THE 1933 ACT. “UNITED STATES” AND “U.S. PERSON” ARE AS DEFINED BY
REGULATION S UNDER THE 1933 ACT.” 

10Orgenesis Inc. - Exhibit 10.1 - Filed by newsfilecorp.com

ORGENESIS INC. 
(the “Issuer”) 

PRIVATE PLACEMENT SUBSCRIPTION AGREEMENT 

(CONVERTIBLE NOTE) 

INSTRUCTIONS TO SUBSCRIBER 

1.        You must complete
all the information in the boxes on page 2 and sign where indicated with an
“X”. 

2.        If you are a “U.S.
Purchaser”, as defined in Exhibit A, you must complete and sign Exhibit A
“United States Accredited Investor Questionnaire”. 

3.        If you are paying
for your subscription with funds drawn from a U.S. bank or Non U.S. source, you
may pay by by wire transfer to the Issuer pursuant to the wiring instructions
set out in Exhibit B. 

ORGENESIS INC. 
PRIVATE
PLACEMENT SUBSCRIPTION AGREEMENT 

The undersigned (the “Subscriber”) hereby irrevocably
subscribes for and agrees to purchase from Orgenesis Inc. (the “Issuer”)
a 2% Unsecured Convertible Note of the Issuer (the “Note”) in the
principal amount set forth below. The form of the Note is attached to this
Subscription Agreement as Exhibit C. The Subscriber agrees to be bound by
the terms and conditions set forth in the attached “Terms and Conditions of
Subscription for Note”. 

	Subscriber Information 	 	Note to be Purchased 
	 
    	 	 
	  	 	Principal Amount of Note: $
      125,000________
	 
    	 	 
	(Name of Subscriber) 	 	 
	 
    	 	 
	Account Reference (if applicable): ______________________	 	 
	  	 	Total Subscription Price: $125,000 _________
    
	X 	 	(the “Subscription Amount”, plus wire fees
      if 
	(Signature of Subscriber – if the 	 	applicable) 
	Subscriber is an Individual) 	 	 
	 
    	 	 
	 
    	 	 
	 
    	 	 
	X 	 	 
	(Signature of Authorized Signatory – if the 	 	Please complete if purchasing as agent or
  
	Subscriber is not an Individual) 	 	trustee for a principal (beneficial purchaser)
      
	  	 	(a “Disclosed Principal”) and not purchasing
    
	  	 	as trustee or agent for accounts fully managed
      
	(Name and Title of Authorized Signatory – if 	 	by it. 
	the Subscriber is not an Individual) 	 	 
	 	 	 
	 
    	 	 
	(SSN or other Tax Identification Number of 	 	(Name of Disclosed Principal) 
	 	 	 
	the Subscriber) 	 	 
	 
    	 	 
	  	 	(Address of Disclosed Principal) 
	 	 	 
	 
    	 	 
	(Subscriber’s Address, including postal or zip code) 	 	 
	  	 	(Account Reference, if applicable) 
	 	 	 
	 
    	 	 
	(Telephone Number) 	 	 
	(Email Address) 	 	(SSN or other Tax Identification Number of 
	  	 	Disclosed Principal) 

2

	Register the Note as set forth below: 	 	Deliver the Note as set forth below: 
	 
    	 	  
	 
    	 	  
	(Name to Appear on Note Certificate) 	 	(Attention - Name) 
	 
    	 	  
	 
    	 	  
	(Account Reference, if applicable) 	 	(Account Reference, if applicable) 
	 
    	 	  
	 
    	 	  
	  	 	(Street Address, including postal or zip code –
      no 
	(Address, including postal or zip code) 	 	PO Boxes permitted) 
	 
    	 	  
	 
    	 	  
	 
    	 	  
	  	 	(Telephone Number) 
	 
    	 	  
	Number and kind of securities of the Issuer already
      held, directly or indirectly, or over which control or direction is
      exercised by, the Subscriber, if any (i.e.,
      shares, warrants, options): 	  	  
	 	 	 
	 	 	 
	 	 	 

3

ACCEPTANCE 

The Issuer hereby accepts the Subscription (as defined herein)
on the terms and conditions contained in this private placement subscription
agreement (this “Agreement”) as of the 30th day of November, 2018 (the
“Closing Date”). 

ORGENESIS INC. 

 

Per: /s/ Neil
Reithinger 
            
Authorized Signatory 

4

TERMS AND CONDITIONS OF SUBSCRIPTION FOR NOTE

1.       
Subscription 

1.1      On the basis of the
representations and warranties, and subject to the terms and conditions, set
forth in this Agreement and in the form of Note attached as Exhibit C to
this Agreement, the Subscriber hereby irrevocably subscribes for and agrees to
purchase a Note in the principal amount as set forth on page 2 of this Agreement
for the Subscription Amount shown on page 2 of this Agreement, which is tendered
herewith (such subscription and agreement to purchase being the
“Subscription”), and the Issuer agrees to sell the Note to the
Subscriber, effective upon the Issuer’s acceptance of this Agreement. 

1.2      The principal amount of the
Note will accrue interest at 2% per annum. The Note will be an unsecured
obligation of the Issuer. The Subscriber hereby confirms and acknowledges that
the Issuer may use the Subscription Amount, either in part or in full, in any
manner as the Issuer deems advisable including, without limitation, to issue
that certain convertible promissory note in the amount of $1,000,000 to
Hemogenyx (or an affiliate thereof). Subject to Section 3 of the Note, within
two (2) years from the date hereof (the “Conversion Period”), the
Subscriber shall be entitled, at its option, to convert, at any time and from
time to time, until payment in full of the Note, all or any portion of the
outstanding principal amount of the Note, plus accrued and unpaid interest
thereon, into either of the following (as shall be determined by the Subscriber
in his discretion):

	 	1.2.1 	
      Units of the Issuer. The term “Units” shall mean
      one (1) share (each, a “Conversion Share”) of the Issuer’s common
      stock, par value $0.0001 per share (the “Common Stock”), and one
      warrant to purchase one share of Common Stock (the “Warrants”).
      Each Warrant shall entitle the holder to purchase one share of Common
      Stock (the “Warrant Shares”) at an exercise price of $7.00 per
      share (the “Exercise Price”), subject to adjustment, and shall be
      exercisable for a period of three years from the date hereof.

	 	 	 
	 	1.2.2 	
      shares of capital stock of Hemogenyx at a price per share
      based on a pre-money valuation of Hemogenyx of $12,000,000 (the
      “Hemogenyx Securities”, and collectively with the Note, Conversion
      Shares, Warrant and Warrant Shares referred to herein as the
      “Securities”).

1.3      In the event the Subscriber
does not elect to convert the principal amount of the Note, plus accrued and
unpaid interest thereon, into Hemogenyx Securities during the Conversion Period,
the Conversion Period shall be extended by an additional one (1) year during
which the Subscriber may convert the principal amount of the Note, plus accrued
and unpaid interest thereon, solely into Units. In no event may the Subscriber
convert such amounts into Hemogenyx Securities after the expiration of the
Conversion Period. 

1.4      The Subscriber acknowledges
that the Note has been offered to the Subscriber as part of an offering (the
“Offering”) in which the Issuer intends to sell up to an aggregate of
$10,000,000 of principal amount of the Notes on the same terms as set forth in
this Agreement. 

1.5      All dollar amounts referred
to in this Agreement are in lawful money of the United States of America, unless
otherwise indicated. 

2.      
 Payment

2.1      Payment of the Aggregate
Subscription Price is required upon submission of the subscription documents.

5

2.2      The Subscriber acknowledges
and agrees that this Agreement, the Subscription Amount and any other documents
delivered in connection herewith will be held by or on behalf of the Issuer. In
the event that this Agreement is not accepted by the Issuer for whatever reason,
which the Issuer expressly reserves the right to do, the Issuer will return the
Subscription Amount (without interest thereon) to the Subscriber at the address
of the Subscriber as set forth on page 2 of this Agreement, or as otherwise
directed by the Subscriber. 

3.        Documents
Required from Subscriber

3.1      The Subscriber must complete,
sign and return to the Issuer the following documents: 

           
(a)      this Agreement; 

         
  (b)      if the Subscriber is a U.S.
Purchaser (as defined in Exhibit A), the United States Accredited
Investor Questionnaire (the “Questionnaire”) attached as Exhibit
A; 

       
    (c)      such other supporting
documentation that the Issuer or the Issuer’s Counsel may request to establish
the Subscriber’s qualification as a qualified investor; and 

      
     (d)      the Subscriber
acknowledges and agrees that the Issuer will not consider the Subscription for
acceptance unless the Subscriber has provided all of such documents to the
Issuer. 

3.2      As soon as practicable upon
any request by the Issuer, the Subscriber will complete, sign and return to the
Issuer any additional documents, questionnaires, notices and undertakings as may
be required by any regulatory authorities or applicable laws. 

3.3      The Issuer and the Subscriber
acknowledge and agree that the Issuer’s Counsel has acted as counsel only to the
Issuer and is not protecting the rights and interests of the Subscriber. The
Subscriber acknowledges and agrees that the Issuer and the Issuer’s Counsel have
given the Subscriber the opportunity to seek, and are hereby recommending that
the Subscriber obtain, independent legal advice with respect to the subject
matter of this Agreement and, further, the Subscriber hereby represents and
warrants to the Issuer and the Issuer’s Counsel that the Subscriber has sought
independent legal advice or waives such advice. 

4.        Conditions
and Closing

The Subscriber acknowledges that the Note will be available for
delivery within five (5) Business Days of the Issuer’s acceptance of the
subscription hereunder, provided that the Subscriber has satisfied the
requirements of Section 3 hereof and the Issuer has accepted this Agreement.

5.       
Acknowledgements and Agreements of the Subscriber

The Subscriber acknowledges and agrees that: 

          (a)     
none of the Securities have been or will be registered under the United States
Securities Act of 1933, as amended, (the “1933 Act”), or under any
securities or “blue sky” laws of any state of the United States, and, unless so
registered, may not be offered or sold in the United States or, directly or
indirectly, to any U.S. Person (as defined in Section 902 of Regulation S),
except in accordance with the provisions of Regulation S under the 1933 Act
(“Regulation S”), pursuant to an effective registration statement under
the 1933 Act, or pursuant to an exemption from, or in a transaction not subject
to, the registration requirements of the 1933 Act, and in each case
only in accordance with applicable securities laws; 

6

          (b)     
the Issuer has not undertaken, and will have no obligation, to register any of
the Securities under the 1933 Act or any other applicable securities laws;

          (c)     
the Issuer will refuse to register the transfer of any of the Securities to a
U.S. Person not made pursuant to an effective registration statement under the
1933 Act or pursuant to an available exemption from the registration
requirements of the 1933 Act and in each case in accordance with applicable
laws; 

          (d)     
the decision to execute this Agreement and to acquire the Securities has not
been based upon any oral or written representation as to fact or otherwise made
by or on behalf of the Issuer and such decision is based entirely upon a review
of any public information which has been filed by the Issuer with the United
States Securities and Exchange Commission (the “SEC”) (collectively, the
“Public Record”); 

          (e)     
the Issuer and others will rely upon the truth and accuracy of the
acknowledgements, representations, warranties, covenants and agreements of the
Subscriber contained in this Agreement and the Questionnaire, as applicable, and
agrees that if any of such acknowledgements, representations and agreements are
no longer accurate or have been breached, the Subscriber will promptly notify
the Issuer; 

          (f)     
there are risks associated with the purchase of the Securities, as more fully
described in the Public Record; 

          (g)     
the Subscriber and the Subscriber’s advisor(s) have had a reasonable opportunity
to ask questions of, and receive answers from, the Issuer in connection with the
distribution of the Securities hereunder, and to obtain additional information,
to the extent possessed or obtainable without unreasonable effort or expense,
necessary to verify the accuracy of the information about the Issuer; 

          (h)     
a portion of the Offering may be sold pursuant to an agreement between the
Issuer and one or more agents registered in accordance with applicable
securities laws, in which case the Issuer will pay a fee and/or compensation
security on terms as set out in such agreement; 

          (i)     
finder’s fees or broker’s commissions may be payable by the Issuer to finders
who introduce subscribers to the Issuer; 

          (j)     
the books and records of the Issuer were available upon reasonable notice for
inspection, subject to certain confidentiality restrictions, by the Subscriber
during reasonable business hours at its principal place of business, and all
documents, records and books in connection with the distribution of the
Securities hereunder have been made available for inspection by the Subscriber,
its legal counsel and/or its advisor(s); 

          (k)     
all of the information which the Subscriber has provided to the Issuer is
correct and complete and if there should be any change in such information prior
to the Closing, the Subscriber will immediately notify the Issuer, in writing,
of the details of any such change; 

          (l)     
the Issuer is entitled to rely on the representations and warranties of the
Subscriber contained in this Agreement and the Questionnaire, as applicable, and
the Subscriber will hold harmless the Issuer from any loss or damage it or they
may suffer as a result of the Subscriber’s failure to correctly complete this
Agreement or the Questionnaire, as applicable; 

7

          (m)     
any resale of the Securities by the Subscriber will be subject to resale
restrictions contained in the securities laws applicable to the Issuer, the
Subscriber and any proposed transferee, including resale restrictions imposed
under United States securities laws and additional restrictions on the
Subscriber’s ability to resell any of the Securities in any other jurisdiction
under applicable securities laws; 

          (n)     
it is the responsibility of the Subscriber to find out what any applicable
resale restrictions are and to comply with such restrictions before selling any
of the Securities; 

          (o)     
the Subscriber has been advised to consult the Subscriber’s own legal, tax and
other advisors with respect to the merits and risks of an investment in the
Securities and with respect to applicable resale restrictions, and it is solely
responsible (and the Issuer is not in any way responsible) for compliance with:

                    (i)     
any applicable laws of the jurisdiction in which the Subscriber is resident in
connection with the distribution of the Securities hereunder, and 

                   
(ii)      applicable resale restrictions;

(p)      there may be material tax
consequences to the Subscriber of an acquisition or disposition of the
Securities and the Issuer gives no opinion and makes no representation to the
Subscriber with respect to the tax consequences to the Subscriber under federal,
state, provincial, local or foreign tax laws that may apply to the Subscriber’s
acquisition or disposition of the Securities; 

(q)      the Issuer has advised the
Subscriber that the Issuer is relying on an exemption from the requirements to
provide the Subscriber with a prospectus and to offer or sell the Securities
through a person registered to sell securities under applicable securities laws,
and, as a consequence of acquiring the Securities pursuant to such exemption,
certain protections, rights and remedies provided by applicable securities laws,
including statutory rights of rescission or damages, may not be available to the
Subscriber; 

(r)      no documents in connection
with the issuance of the Securities have been reviewed by the SEC or any other
securities regulators; 

(s)      neither the SEC nor any other
securities commission or similar regulatory authority has reviewed or passed on
the merits of any of the Securities; 

(t)      there is no government or
other insurance covering any of the Securities; 

(u)      hedging transactions
involving the Securities may not be conducted unless such transactions are in
compliance with the provisions of the 1933 Act and in each case only in
accordance with applicable securities laws; and 

(v)      this Agreement is not
enforceable by the Subscriber unless it has been accepted by the Issuer and the
Issuer reserves the right to reject this Subscription for any reason. 

6.       
Representations and Warranties of the Subscriber

The Subscriber hereby represents and warrants to the Issuer
(which representations and warranties will survive the Closing) that: 

8

         
(a)      Unless the Subscriber has completed Exhibit
A, the Subscriber is not a U.S. Purchaser; 

          (b) the Subscriber is resident in
  the jurisdiction set out on page 2 of this Agreement; 

          (c) if the Subscriber is
  resident outside of the United States: 

                         (i)     
the Subscriber is knowledgeable of, or has been independently advised as to, the
applicable securities laws having application in the jurisdiction in which the
Subscriber is resident (the “International Jurisdiction”) which would
apply to the offer and sale of the Securities; 

                         (ii)     
the Subscriber is purchasing the Securities pursuant to exemptions from
prospectus or equivalent requirements under applicable laws of the International
Jurisdiction or, if such is not applicable, the Subscriber is permitted to
purchase the Securities under applicable securities laws of the International
Jurisdiction without the need to rely on any exemptions; 

                         (iii)     
the applicable laws and regulations of the International Jurisdiction do not and
will not require the Issuer to make any filings or seek any approvals of any
kind from any securities regulator of any kind in the International Jurisdiction
in connection with the offer, issue, sale or resale of any of the Securities;

                        
(iv)      the purchase of the Securities by the
Subscriber does not trigger: 

	 	A. 	
      any obligation to prepare and file a prospectus or
      similar document, or any other report with respect to such purchase in the
      International Jurisdiction, or

	 	 	 
	 	B. 	
      any continuous disclosure reporting obligation of the
      Issuer in the International Jurisdiction, and

                         (v)     
the Subscriber will, if requested by the Issuer, deliver to the Issuer a
certificate or opinion of local counsel from the International Jurisdiction
which will confirm the matters referred to in subparagraphs (ii), (iii) and (iv)
above to the satisfaction of the Issuer, acting reasonably; 

          (d)     
the Subscriber: (i) has adequate net worth and means of providing for its
current financial needs and possible personal contingences, (ii) has no need for
liquidity in this investment, (iii) has such knowledge and experience in
business matters as to be capable of evaluating the merits and risks of its
prospective investment in the Securities, (iv) is able to bear the economic
risks of an investment in the Securities for an indefinite period of time, and
(v) can afford the complete loss of the Subscription Amount; 

          (e)     
the Subscriber has the legal capacity and competence to enter into and execute
this Agreement and to take all actions required pursuant hereto and, if the
Subscriber is a corporate entity, it is duly incorporated and validly subsisting
under the laws of its jurisdiction of incorporation and all necessary approvals
by its directors, shareholders and others have been obtained to authorize
execution and performance of this Agreement on behalf of the Subscriber; 

          (f)     
the entering into of this Agreement and the transactions contemplated hereby do
not and will not result in the violation of any of the terms and provisions of
any law applicable to, and, if applicable, any of the constating documents of,
the Subscriber or of any agreement, written or oral, to which the Subscriber may
be a party or by which the Subscriber is or may be bound; 

9

         
(g)      the Subscriber has duly executed and delivered
this Agreement and it constitutes a valid and binding agreement of the
Subscriber enforceable against the Subscriber; 

         
(h)      the Subscriber has received and carefully read
this Agreement; 

          (i)     
the Subscriber is aware that an investment in the Issuer is speculative and
involves certain risks, including those risks disclosed in the Public Record and
the possible loss of the entire Subscription Amount; 

          (j)     
the Subscriber has made an independent examination and investigation of an
investment in the Securities and the Issuer and agrees that the Issuer will not
be responsible in any way for the Subscriber’s decision to invest in the
Securities and the Issuer; 

          (k)     
the Subscriber is not an underwriter of, or dealer in, any of the Securities,
nor is the Subscriber participating, pursuant to a contractual agreement or
otherwise, in the distribution of the Securities; 

          (l)     
the Subscriber is purchasing the Securities for its own account for investment
purposes only and not for the account of any other person and not for
distribution, assignment or resale to others, and no other person has a direct
or indirect beneficial interest in such Securities, and the Subscriber has not
subdivided its interest in any of the Securities with any other person; 

          (m)     
the Subscriber is not aware of any advertisement of any of the Securities and is
not acquiring the Securities as a result of any form of general solicitation or
general advertising, including advertisements, articles, notices or other
communications published in any newspaper, magazine or similar media, or
broadcast over radio or television, or any seminar or meeting whose attendees
have been invited by general solicitation or general advertising;

          (n)     
the Subscriber has not acquired the Securities as a result of, and will not
itself engage in, any “directed selling efforts” (as defined in Regulation S) in
the United States in respect of any of the Securities which would include any
activities undertaken for the purpose of, or that could reasonably be expected
to have the effect of, conditioning the market in the United States for the
resale of any of the Securities, provided, however, that the Subscriber may sell
or otherwise dispose of any of the Securities pursuant to registration of any of
the Securities pursuant to the 1933 Act and any applicable securities laws or
under an exemption from such registration requirements; and 

         
(o)      no person has made to the Subscriber any
written or oral representations: 

                     
(i)      that any person will resell or repurchase any
of the Securities, 

                     
(ii)      that any person will refund the purchase
price of any of the Securities, or 

                     
(iii)      as to the future price or value of any of
the Securities. 

In this Agreement, the term “U.S. Person” will have the
meaning ascribed thereto in Regulation S, and for the purpose of this Agreement
includes, but is not limited to: (a) any person in the United States; (b) any
natural person resident in the United States; (c) any partnership or corporation
organized or incorporated under the laws of the United States; (d) any
partnership or corporation organized outside the United States by a U.S. Person
principally for the purpose of investing in securities not registered under the
1933 Act, unless it is organized or incorporated, and owned, by accredited
investors who are not natural persons, estates or trusts; or (e) any estate or trust
of which any executor or administrator or trustee is a U.S. Person. 

10

          (p)     
The Subscriber should check the Office of Foreign Assets Control (“OFAC”)
website at <http://www.treas.gov/ofac> before making the following
representations.

                   
(i)      The Subscriber represents that the amounts
invested by it in the Issuer in the offering were not and are not
directly or indirectly derived from activities that contravene federal, state or
international laws and regulations, including anti-money laundering laws and
regulations. Federal regulations and Executive Orders administered by OFAC
prohibit, among other things, the engagement in transactions with, and the
provision of services to, certain foreign countries, territories, entities and
individuals. The lists of OFAC prohibited countries, territories, persons and
entities can be found on the OFAC website at< http://www.treas.gov/ofac. In
addition, the programs administered by OFAC (the “OFAC Programs”) prohibit
dealing with individuals1 or entities in certain countries regardless
of whether such individuals or entities appear on the OFAC lists; 

                   
(ii)      To the best of the Subscriber’s knowledge,
none of: (1) the Subscriber; (2) any person controlling or controlled by the
Subscriber; (3) if the Subscriber is a privately-held entity, any person having
a beneficial interest in the Subscriber; or (4) any person for whom the
Subscriber is acting as agent or nominee in connection with this investment is a
country, territory, individual or entity named on an OFAC list, or a person or
entity prohibited under the OFAC Programs. You are advised that the Issuer may
not accept any amounts from a prospective investor if such prospective investor
cannot make the representation set forth in the preceding paragraph. The
Subscriber agrees to promptly notify the Issuer should the Subscriber become
aware of any change in the information set forth in these representations. The
Subscriber understands and acknowledges that, by law, the Issuer may be
obligated to “freeze the account” of the Subscriber, either by prohibiting
additional subscriptions from the Subscriber, declining any redemption requests
and/or segregating the assets in the account in compliance with governmental
regulations. These individuals include specially designated nationals, specially
designated narcotics traffickers and other parties subject to OFAC sanctions and
embargo programs; 

                    (iii)      To the best of the Subscriber’s knowledge,
none of: (1) the Subscriber; (2) any person controlling or controlled by the
Subscriber`; (3) if the Subscriber is a privately-held entity, any person having
a beneficial interest in the Subscriber; or (4) any person for whom the
Subscriber is acting as agent or nominee in connection with this investment is a
senior foreign political figure,2 or any immediate family3
member or close associate4 of a senior foreign political figure, as
such terms are defined in the footnotes below; and 

1 These individuals include specially designated
nationals, specially designated narcotics traffickers and other parties subject
to OFAC sanctions and embargo programs. 
2 A “senior foreign
political figure” is defined as a senior official in the executive, legislative,
administrative, military or judicial branches of a foreign government (whether
elected or not), a senior official of a major foreign political party, or a
senior executive of a foreign government-owned corporation. In addition, a
“senior foreign political figure” includes any corporation, business or other
entity that has been formed by, or for the benefit of, a senior foreign
political figure. 
3 “Immediate family” of a senior foreign
political figure typically includes the figure’s parents, siblings, spouse,
children and in-laws. 
4 A “close associate” of a senior foreign
political figure is a person who is widely and publicly known to maintain an
unusually close relationship with the senior foreign political figure and
includes a person who is in a position to conduct substantial domestic and
international financial transactions on behalf of the senior foreign political
figure. 

11

                    (iv)
If the Subscriber is affiliated with a non-U.S. banking institution (a “Foreign
Bank”), or if the Subscriber receives deposits from, makes payments on behalf
of, or handles other financial transactions related to a Foreign Bank, the
Subscriber represents and warrants to the Issuer that: (1) the Foreign Bank has
a fixed address, other than solely an electronic address, in a country in which
the Foreign Bank is authorized to conduct banking activities; (2) the Foreign
Bank maintains operating records related to its banking activities; (3) the
Foreign Bank is subject to inspection by the banking authority that licensed the
Foreign Bank to conduct banking activities; and (4) the Foreign Bank does not
provide banking services to any other Foreign Bank that does not have a physical
presence in any country and that is not a regulated affiliate 

7.           
 Representations and Warranties will be Relied Upon by the
Issuer

The Subscriber acknowledges and agrees that the representations
and warranties contained in this Agreement and the Questionnaire, as applicable,
are made by it with the intention that such representations and warranties may
be relied upon by the Issuer and the Issuer’s Counsel in determining the
Subscriber’s eligibility to purchase the Securities under applicable laws, or,
if applicable, the eligibility of others on whose behalf the Subscriber is
contracting hereunder to purchase the Securities under applicable laws. The
Subscriber further agrees that, by accepting delivery of the certificate
representing the Note, it will be representing and warranting that the
representations and warranties contained herein are true and correct as at the
Closing Date with the same force and effect as if they had been made by the
Subscriber on the Closing Date and that they will survive the purchase by the
Subscriber of the Securities and will continue in full force and effect
notwithstanding any subsequent disposition by the Subscriber of such Securities.

8.            
Acknowledgement and Waiver

The Subscriber has acknowledged that the decision to acquire
the Securities was solely made on the basis of the Public Record. The Subscriber
hereby waives, to the fullest extent permitted by law, any rights of withdrawal,
rescission or compensation for damages to which the Subscriber might be entitled
in connection with the distribution of any of the Securities. 

9.         
   Legending of Securities

The Subscriber hereby acknowledges that, upon the issuance
thereof, and until such time as the same is no longer required under applicable
securities laws, any certificates representing any of the Securities will bear a
legend in substantially the following form: 

“NONE OF THE SECURITIES REPRESENTED HEREBY HAVE BEEN REGISTERED
UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE “1933 ACT”), OR
ANY U.S. STATE SECURITIES LAWS, AND, UNLESS SO REGISTERED, NONE MAY BE OFFERED
OR SOLD, DIRECTLY OR INDIRECTLY, IN THE UNITED STATES OR TO U.S. PERSONS EXCEPT
IN ACCORDANCE WITH THE PROVISIONS OF REGULATION S UNDER THE 1933 ACT, PURSUANT
TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE 1933 ACT, OR PURSUANT TO AN
EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION
REQUIREMENTS OF THE 1933 ACT AND IN EACH CASE ONLY IN ACCORDANCE WITH APPLICABLE
SECURITIES LAWS.” 

12

The Subscriber hereby acknowledges and agrees to the Issuer
making a notation on its records or giving instructions to the registrar and
transfer agent of the Issuer in order to implement the restrictions on transfer
set forth and described in this Agreement. 

10.          
Collection of Personal Information

               10.1     
The Subscriber acknowledges and consents to the fact that the Issuer is
collecting the Subscriber’s personal information for the purpose of fulfilling
this Agreement and completing the Offering. The Subscriber acknowledges that its
personal information (and, if applicable, the personal information of those on
whose behalf the Subscriber is contracting hereunder) may be included in record
books in connection with the Offering and may be disclosed by the Issuer to: (a)
stock exchanges or securities regulatory authorities, (b) the Issuer's registrar
and transfer agent, (c) tax authorities, (d) authorities pursuant to the PATRIOT
Act (U.S.A.) and (e) any of the other parties involved in the Offering,
including the Issuer’s Counsel. By executing this Agreement, the Subscriber is
deemed to be consenting to the foregoing collection, use and disclosure of the
Subscriber's personal information (and, if applicable, the personal information
of those on whose behalf the Subscriber is contracting hereunder) for the
foregoing purposes and to the retention of such personal information for as long
as permitted or required by applicable laws. Notwithstanding that the Subscriber
may be purchasing the Note as agent on behalf of an undisclosed principal, the
Subscriber agrees to provide, on request, particulars as to the nature and
identity of such undisclosed principal, and any interest that such undisclosed
principal has in the Issuer, all as may be required by the Issuer in order to
comply with the foregoing. 

               10.2     
Furthermore, the Subscriber is hereby notified that the Issuer may deliver to
any government authority having jurisdiction over the Issuer, the Subscriber or
this Subscription, including the SEC and/or any state securities commissions,
certain personal information pertaining to the Subscriber, including the
Subscriber’s full name, residential address and telephone number, the number of
Shares or other securities of the Issuer owned by the Subscriber, the principal
amount of Note purchased by the Subscriber, the total Subscription Amount paid
for the Note and the date of distribution of the Note. 

11.          
Costs

The Subscriber acknowledges and agrees that all costs and
expenses incurred by the Subscriber (including any fees and disbursements of any
special counsel retained by the Subscriber) relating to the purchase of the Note
will be borne by the Subscriber. 

12.          
Governing Law

This Agreement is governed by the laws of the State of Nevada
(without reference to its rules governing the choice or conflict of laws). 

13.          
Survival

This Agreement, including, without limitation, the
representations, warranties and covenants contained herein, will survive and
continue in full force and effect and be binding upon the Issuer and the
Subscriber, notwithstanding the completion of the purchase of the Securities by
the Subscriber. 

14.          
Assignment

This Agreement is not transferable or assignable. 

13

15.          
Severability 

The invalidity or unenforceability of any particular provision
of this Agreement will not affect or limit the validity or enforceability of the
remaining provisions of this Agreement. 

16.          
Entire Agreement

Except as expressly provided in this Agreement and in the
exhibits, agreements, instruments and other documents attached hereto or
contemplated or provided for herein, this Agreement contains the entire
agreement between the parties with respect to the sale of the Securities and
there are no other terms, conditions, representations or warranties, whether
expressed, implied, oral or written, by statute or common law, by the Issuer or
by anyone else. 

17.          
Notices

All notices and other communications hereunder will be in
writing and will be deemed to have been duly given if hand delivered or
transmitted by any standard form of telecommunication, including facsimile,
electronic mail or other means of electronic communication capable of producing
a printed copy. Notices to the Subscriber will be directed to the address of the
Subscriber set forth on page 2 of this Agreement and notices to the Issuer will
be directed to it at the address of the Issuer set forth on page 3 of this
Agreement. 

18.          
Counterparts and Electronic Means

This Agreement may be executed in any number of counterparts,
each of which, when so executed and delivered, will constitute an original and
all of which together will constitute one instrument. Delivery of an executed
copy of this Agreement by electronic facsimile transmission or other means of
electronic communication capable of producing a printed copy will be deemed to
be execution and delivery of this Agreement as of the Closing Date. 

19.          
Exhibits

The exhibits attached hereto form part of this Agreement. 

20.          
Indemnity

The Subscriber will indemnify and hold harmless the Issuer and,
where applicable, its directors, officers, employees, agents, advisors and
shareholders, from and against any and all loss, liability, claim, damage and
expense whatsoever (including, but not limited to, any and all fees, costs and
expenses whatsoever reasonably incurred in investigating, preparing or defending
against any claim, lawsuit, administrative proceeding or investigation whether
commenced or threatened) arising out of or based upon any representation or
warranty of the Subscriber contained in this Agreement, the Questionnaire or in
any document furnished by the Subscriber to the Issuer in connection herewith
being untrue in any material respect, or any breach or failure by the Subscriber
to comply with any covenant or agreement made by the Subscriber to the Issuer in
connection therewith. 

14

EXHIBIT A 

UNITED STATES ACCREDITED INVESTOR QUESTIONNAIRE

Capitalized terms used in this Questionnaire (this
“Questionnaire”) and not specifically defined have the meaning ascribed
to them in the Private Placement Subscription Agreement (the “Agreement”)
between the Subscriber and the Issuer to which this Exhibit A is attached. 

This Questionnaire applies only to persons that are U.S.
Purchasers. A “U.S. Purchaser” is: (a) any U.S. Person, (b) any person
purchasing the Note on behalf of any U.S. Person, (c) any person that receives
or received an offer of the Note while in the United States, or (d) any person
that is in the United States at the time the Subscriber’s buy order was made or
this Agreement was executed or delivered. 

The Subscriber understands and agrees that none of the
Securities have been or will be registered under the 1933 Act, or applicable
state, provincial or foreign securities laws, and the Securities are being
offered and sold to the Subscriber in reliance upon the exemption provided in
Section 4(a)(2) of the 1933 Act and Rule 506 of Regulation D under the 1933 Act
for non-public offerings. The Securities are being offered and sold within the
United States only to “accredited investors” as defined in Rule 501(a) of
Regulation D. The Securities offered hereby are not transferable except in
accordance with the restrictions described herein and the Agreement. 

The Subscriber represents, warrants, covenants and certifies
(which representations, warranties, covenants and certifications will survive
the Closing) to the Issuer (and acknowledges that the Issuer is relying thereon)
that: 

1.          
it has such knowledge and experience in financial and business matters as to be
capable of evaluating the merits and risks of an investment in the Securities
and it is able to bear the economic risk of loss of its entire investment; 

2.          
the Issuer has provided to it the opportunity to ask questions and receive
answers concerning the terms and conditions of the Offering and it has had
access to such information concerning the Issuer as it has considered necessary
or appropriate in connection with its investment decision to acquire the
Securities; 

3.          
it is acquiring the Securities for its own account, for investment purposes only
and not with a view to any resale, distribution or other disposition of the
Securities in violation of the United States securities laws; 

4.          
it (i) has adequate net worth and means of providing for its current financial
needs and possible personal contingencies, (ii) has no need for liquidity in
this investment, and (iii) is able to bear the economic risks of an investment
in the Securities for an indefinite period of time; 

5.          
if the Subscriber is an individual (that is, a natural person and not a
corporation, partnership, trust or other entity), then it satisfies one or more
of the categories indicated below (please place an “X” on the appropriate
lines): 

	 	__________	
      a natural person whose individual net worth, or joint net
      worth with that person’s spouse, exceeds US$1,000,000. For purposes of
      this category, "net worth" means the excess of total assets at fair market
      value (including personal and real property, but excluding the estimated
      fair market value of a person's primary home) over total liabilities.
      Total liabilities excludes any 

15

	 	__________	
      mortgage on the primary home in an amount of up to the
      home's estimated fair market value as long as the mortgage was incurred
      more than 60 days before the Securities are acquired, but includes (i) any
      mortgage amount in excess of the home's fair market value and (ii) any
      mortgage amount that was borrowed during the 60-day period before the date
      of the acquisition of Securities for the purpose of investing in the
      Securities; 

	 	 	     
	 	__________	
      a natural person who had an individual income in excess
      of US$200,000 in each of the two most recent years, or joint income with
      their spouse in excess of US$300,000 in each of those years and has a
      reasonable expectation of reaching the same income level in the current
      year, or 

	 	 	     
	 	__________	
      a director or executive officer of the Issuer.
  

6.          
if the Subscriber is a corporation, partnership, trust or other entity), then it
satisfies one or more of the categories indicated below (please place an “X” on
the appropriate lines): 

	 	__________	
      an organization described in Section 501(c)(3) of the
      United States Internal Revenue Code, a corporation, a Massachusetts or
      similar business trust or partnership, not formed for the specific purpose
      of acquiring the Securities, with total assets in excess of US$5,000,000;
      

	 	 	     
	 	__________	
      a “bank” as defined under Section (3)(a)(2) of the 1933
      Act or savings and loan association or other institution as defined in
      Section 3(a)(5)(A) of the 1933 Act acting in its individual or fiduciary
      capacity; a broker dealer registered pursuant to Section 15 of the
      Securities Exchange Act of 1934 (United States); an insurance
      company as defined in Section 2(13) of the 1933 Act; an investment company
      registered under the Investment Company Act of 1940 (United
      States) or a business development company as defined in Section 2(a)(48)
      of such Act; a Small Business Investment Company licensed by the U.S.
      Small Business Administration under Section 301(c) or (d) of the Small
      Business Investment Act of 1958 (United States); a plan with total
      assets in excess of US$5,000,000 established and maintained by a state, a
      political subdivision thereof, or an agency or instrumentality of a state
      or a political subdivision thereof, for the benefit of its employees; an
      employee benefit plan within the meaning of the Employee Retirement
      Income Security Act of 1974 (United States) whose investment decisions
      are made by a plan fiduciary, as defined in Section 3(21) of such Act,
      which is either a bank, savings and loan association, insurance company or
      registered investment adviser, or if the employee benefit plan has total
      assets in excess of US$5,000,000, or, if a self- directed plan, whose
      investment decisions are made solely by persons that are accredited
      investors; 

	 	 	     
	 	__________	
      a private business development company as defined in
      Section 202(a)(22) of the Investment Advisers Act of 1940 (United
      States); 

	 	 	     
	 	__________	
      a trust with total assets in excess of US$5,000,000, not
      formed for the specific purpose of acquiring the Securities, whose
      purchase is directed by a sophisticated person as described in Rule
      506(b)(2)(ii) under the 1933 Act, or 

16

	 	__________	
      an entity in which all of the equity owners satisfy the
      requirements of one or more of the categories set forth in Section 6 of
      this Questionnaire. 

7.            
it has not purchased the Securities as a result of any form of general
solicitation or general advertising, including advertisements, articles, notices
or other communications published in any newspaper, magazine or similar media or
broadcast over radio, internet, television or other form of telecommunications,
or any seminar or meeting whose attendees have been invited by general
solicitation or general advertising; 

8.            
if the Subscriber decides to offer, sell or otherwise transfer any of the
Securities, it will not offer, sell or otherwise transfer any of such
Securities, directly or indirectly, unless: 

              
(a)           the sale is to
the Issuer; 

               (b)          
the sale is made outside the United States in a transaction meeting the
requirements of Rule 904 and 905 of Regulation S under the 1933 Act and in
compliance with applicable local laws and regulations in which such sale is
made; 

               (c)          
the sale is made pursuant to the exemption from the registration requirements
under the 1933 Act provided by Rule 144 thereunder and in accordance with any
applicable state securities or “blue sky” laws; 

               (d)          
the Securities are sold in a transaction that does not require registration
under the 1933 Act or any applicable state laws and regulations governing the
offer and sale of securities; and 

               (e)          
it has, prior to such sale pursuant to subsection (b), (c) or (d), furnished to
the Issuer an opinion of counsel of recognized standing reasonably satisfactory
to the Issuer, to such effect. 

9.           
 it understands and agrees that there may be material tax consequences to
the Subscriber of an acquisition or disposition of the Securities. The Issuer
gives no opinion and makes no representation with respect to the tax
consequences to the Subscriber under United States, state, local or foreign tax
law of the Subscriber’s acquisition or disposition of the Securities; 

10.          
it consents to the Issuer making a notation on its records or giving
instructions to any transfer agent of the Issuer in order to implement the
restrictions on transfer set forth and described in this Questionnaire and the
Agreement; 

11.          
it is resident in the United States of America, its territories and possessions
or any state of the United States or the District of Columbia (collectively the
“United States”), is a “U.S. Person” as such term is defined in
Regulation S or was in the United States at the time the Securities were offered
or the Agreement was executed; and 

12.          
except as contemplated in the Agreement, it understands that the Issuer has no
obligation to register any of the Securities or to take action so as to permit
sales pursuant to the 1933 Act (including Rule 144 thereunder). 

17

The Subscriber undertakes to notify the Issuer immediately of
any change in any representation, warranty or other information relating to the
Subscriber set forth herein which takes place prior to the closing time of the
purchase and sale of the Securities. 

Dated: ___________, 2018. 

	 	X
  
	 	Signature of individual (if Subscriber is an
  
	 	individual) 
	 	  
	 	X
  
	 	Authorized signatory (if Subscriber is not an
    
	 	individual) 
	 	  
	 	  
	 	Name of Subscriber (please print) 
	 	  
	 	  
	 	Name of authorized signatory (please print)
  

18

EXHIBIT B 
INSTRUCTIONS FOR WIRING FUNDS 

 

ORGENESIS INC. 
20271 Goldenrod Lane 
Germantown,
MD 20876 

REMITTANCE INSTRUCTIONS 
JP Morgan Chase Bank 

Account Name: 
Orgenesis Inc. 

Account #: 
000000949139307 

Wire Routing Numbers: 
Domestic – 021000021 

International (also referred to as Swift Code) - CHASUS33 

ACH Routing Numbers: 
022300173 

19

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