Document:

Exhibit 10.5

                     EMPLOYMENT AGREEMENT WITH SAI MING WONG

       EMPLOYMENT  AGREEMENT  ("Agreement")  made and entered into as of the 1st
day  of  July,  2000  by  and  between  AlphaRx  Inc.,  a  Delaware  corporation
("Company"), and Sai Ming Wong ("Executive").

       WHEREAS,  Company  desires  to employ  Executive  as its  Executive  Vice
President  and Executive  desires to be employed by Company,  upon the terms and
conditions hereinafter set forth.

       NOW,  THEREFORE,  in consideration of the mutual covenants and agreements
set forth and the mutual  benefits to be derived  herefrom,  and intending to be
legally bound hereby, the Company and the Executive agree as follows:

1.     Employment  and Term.  Company  hereby  employs  Executive  and Executive
       hereby  accepts  employment  for a term  commencing on July 1st, 2000 and
       continuing  until June 30th, 2003,  unless sooner  terminated as provided
       for  in  this  Agreement.  Company  and  Executive  have  the  option  to
       renegotiate this Agreement beyond the three-year period. Executive hereby
       warrants  and  represents  to Company  that he is free to enter into this
       Agreement and is not a party to any agreement,  written or otherwise,  or
       bound by any restrictions, which limit or restrict him from entering into
       this  Agreement or performing the services,  duties and  responsibilities
       called for hereunder.

2.     Duties.

2.1    Executive shall perform the duties of the Executive Vice President of the
       Company  and  such  additional   executive  duties  of  Company  and  its
       affiliates  as  may  be,  from  time  to  time,  requested  of him by the
       Company's  Board of Directors  or the  Chairman,  President  and/or Chief
       Executive Officer of the Company.

2.2    Executive shall devote his full professional time and best efforts to the
       performance of his duties and  responsibilities  hereunder to advance the
       interests of the Company and shall not during the term of this  Agreement
       (as  defined in  Section 1 hereof) be  employed,  involved  or  otherwise
       engaged in, either directly or indirectly, any other employment for gain,
       profit or other  pecuniary  advantage,  without prior written  consent of
       Company. At no time shall Executive engage in any activity that conflicts
       with the business of the Company or its affiliates.  Nothing set forth in
       this section 2.2 shall be construed to prevent  Executive from (i) acting
       as a member of Board of Trustees or a member of Board of Directors of any
       other  corporation,  or as a  member  of the  Board  of  Trustees  of any
       organization  or entity which is not a competitor  of the Company or (ii)
       devoting of such of  Executive's  time and  attention  to  philanthropic,
       charitable,   civic,  community  or  other  activities  or  endeavors  as
       Executive  shall  reasonably  determine  but  only  to  the  extent  that
       Executive's  pursuance of any activities or endeavors does not materially
       and  adversely  effect the  Executive's  ability to

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       perform and discharge  Executive's  duties and  objectives to the Company
       hereunder.

2.3    Except for required travel on Company  business,  Executive shall perform
       his duties and  responsibilities  at the Company's principal Asia offices
       located in Hong Kong.  The Company  shall furnish  Executive  with office
       space,  secretarial  assistance,  a  personal  computer,  and such  other
       facilities and services as shall be suitable to Executive's  position and
       adequate for the performance of his duties hereunder.

3.     Compensation.  For all duties and responsibilities to be performed and/or
       assumed by Executive hereunder, Executive shall be entitled to receive an
       annual salary as set forth below ("Base Salary").  The Base Salary,  less
       any sums  required  to be  withheld  by law,  shall be  payable  in equal
       monthly  installments or such other more frequent regular installments as
       the Company may, from time to time, determine.  For purposes hereof, Base
       Salary shall be:

3.1.1  For the six-month period commencing with the date hereof, the Base Salary
       shall be $12,000  per year which shall be  increased  to $36,000 per year
       after the first six months of employment

3.1.2  For each year thereafter, the Base Salary shall be increased by an amount
       determined  by the Board of Directors  but in no event less than (i) five
       percent (5%) after the first year, six percent (6%) after the second year
       and seven percent (7%) after the third year and each year thereafter upon
       mutual  agreement  to extend the term.  Each  percentage  increase  for a
       particular  year shall be based on the Base  Salary  for the  immediately
       preceding year.

4.     Fringe  Benefits.  Company  shall pay for or provide  Executive  with the
       following benefits:

4.1    For the first year,  Executive  shall be entitled to three (3) weeks paid
       vacation to be used at the Executive's discretion.  Thereafter, Executive
       shall be entitled to four (4) weeks paid  vacation  during each full year
       of this Agreement to be used at the Executives discretion.  Vacation time
       shall accrue on a pro-rata basis during each year of this Agreement.  Any
       unused  vacation shall be cumulative  from year to year unless  otherwise
       agreed upon by the parties.

4.2    Health and  hospitalization  insurance  established and maintained by the
       Company for its senior executives and key management personnel. Since the
       Company  presently  does not  have,  in  effect,  a plan for  health  and
       hospitalization  insurance,  Company  shall  reimburse  Executive for all
       medical  payments  made by Executive to his previous  employer for health
       and  hospitalization  coverage for Executive and his family.  Thereafter,
       Company  shall  either  secure and  maintain  health and  hospitalization
       insurance  for Executive  and his  dependents or reimburse  Executive for
       coverage  comparable  to Blue  Shield/Blue  Cross for  Executive  and his
       immediate family.

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4.3    Such other  employee  benefits  maintained  by the Company for its senior
       executives and key management employees,  including,  all pension, profit
       sharing,  retirement,  stock bonus and stock option plans,  to the extent
       Executive is eligible to participate pursuant to the terms and conditions
       of such plans.

4.4    Executive shall be reimbursed in a timely manner for all items of travel,
       entertainment  and  miscellaneous  expenses  which  Executive  reasonably
       incurs  in  connection  with the  performance  of his  duties  hereunder,
       provided that the Executive  submits to the Company such  statements  and
       other  evidence  supporting  said  expenses as the Company my  reasonably
       require.   Executive,  when  traveling  on  Company  business,  shall  be
       permitted to fly economy class on all domestic flights and business class
       on all international flights with at least 4 hours of flight time.

5.     Stock Options.

5.1    As  part  of  Executive's   compensation  for  services  to  be  rendered
       hereunder,  Executive  shall have the right and option to  purchase  from
       Company  voting common stock in Company  ("Option").  The total number of
       shares  available to  Executive  under this Option is One Hundred & Fifty
       Thousand  Shares  (150,000) at a purchase  price of Ten Cents ($0.10) per
       share ("Option Shares").  The Option Shares are available for purchase in
       installments  as  listed in  Column A below  and each  installment  shall
       become vested on the corresponding date listed in Column B, as follows:

       Column A                 Column B
       Number of Shares         Date Option Shares Available for Purchase
                                Become Vested

       37,500                   Upon the commencement of Executive's
                                employment pursuant to the terms of this
                                Agreement

       37,500                   First anniversary date of this Agreement

       37,500                   Second anniversary date of this Agreement

       37,500                   Third Anniversary date of this Agreement

In order for the Option Shares to become vested as provided for above, Executive
must be  employed  by the Company  under the terms of this  Agreement  as of the
vesting date set forth in Column B above.

5.2    Except as otherwise  provided for below,  the term of the Option  granted
       shall  remain in effect  for ten (10)  years  from the date on which such
       Option Shares  become  vested.  If the  Executive's  employment  with the
       Company is terminated

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<PAGE>

       by the Company for Cause (as defined  herein) or by the act of Executive,
       the  Executive's  right to exercise  vested Option Shares shall cease and
       become  null and void  within  thirty  (30)  days of the date  employment
       terminated,  except as  otherwise  provided in Section  5.3  hereof.  All
       unvested Option Shares will terminate  immediately as of the date of such
       termination of employment. In the event the Company receives, accepts and
       consummates a tender offer for all of its outstanding  common stock prior
       to the  vesting  of the  Option  Shares,  the  vesting  rights  shall  be
       accelerated  so as to allow  Executive to exercise the Option to purchase
       all of the Option Shares  immediately  prior to the  consummation of such
       tender offer.

5.3    Notwithstanding  anything  in  this  Section  5 to the  contrary,  if the
       Executive's  employment is terminated for Cause,  as set forth in Section
       6.3,  the Company  shall have the right to  terminate  and  withdraw  any
       vested or unvested Options under this Agreement.

5.4    The  purchase  price of the Option  Shares shall be paid in full upon the
       exercise  of the  Option,  and  Company  shall not be required to deliver
       certificates  for such Option  Shares  until  payment  has been made.  In
       addition  to, and at the time of payment of the  purchase  price for such
       Option Shares,  Executive  shall be responsible for all federal and state
       withholding or other employment taxes applicable to the taxable income of
       such  Executive  and any other fees  resulting  from the  exercise of the
       Executive.

5.5    Each share of Option Stock  purchased  pursuant to the terms hereof shall
       carry  all  appropriate  registration  and/or  restrictions  on sale  and
       notices as determined from time to time by Company's  securities counsel.
       Executive shall cooperate with Company and Company's counsel in complying
       with all applicable securities laws.

6.     Termination  of  Employment.  The  employment  of Executive and Company's
       liability and obligations hereunder shall terminate as follows:

6.1    This Agreement shall terminate  immediately  upon the death of Executive.
       In  such  event,  Company  shall  pay to such  person  as  Executive  may
       designate  in a written  notice  filed  with the  Company,  or if no such
       person  shall be  designated,  to  Executive's  estate,  a lump sum death
       benefit in an amount  equal to twelve  (12)  months of  Executive's  Base
       Salary as in effect on the date of Executive's death and double indemnity
       in event Executive's death occurs while traveling on Company business.

6.2    This  Agreement  shall  terminate  immediately  upon  the  Disability  of
       Executive.  Disability  shall  exist  if  due  to a  mental  or  physical
       condition, Executive is determined to be unable to perform his duties and
       responsibilities  hereunder  for a  continuous  period of two (2) months.
       Disability shall be conclusively  established by written certification by
       two (2) licensed,  disinterested  physicians  selected as mutually agreed
       upon between  Company and Executive.  In the event the two (2)

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       physicians  disagree,  a third  physician  shall be  selected  by the two
       physicians  to  break  such  impasse.   The  costs  associated  with  the
       determination  of Disability  shall be borne equally  between Company and
       Executive.  In the event of  Disability,  Executive  shall be entitled to
       receive his Base Salary in accordance  with Section 3 for a period of six
       (6) months following the onset of Disability.

6.3    The Company may discharge the Executive for Cause and thereby immediately
       terminate  his  employment  under this  Agreement.  For  purposes of this
       Agreement,  Company  shall have  "Cause"  to  terminate  the  Executive's
       employment if the Executive, in the reasonable judgment of the Company:

6.3.1  Willfully  fails to perform any  reasonable  directive  of the  Company's
       Board of Directors, Chairman or Chief Executive Officer.

6.3.2  Materially  breaches any of the agreements,  duties,  responsibilities or
       obligations under this Agreement.

6.3.3  Embezzles or converts to his own use any funds or property of the Company
       or any client or customer of the Company.

6.3.4  Is convicted of a felony or any crime involving larceny,  embezzlement or
       moral turpitude.

6.4    In the event that  Executive's  employment  is  terminated by the Company
       without Cause, as defined in Section 6.3, above,  for a reason other than
       death or  Disability,  or Executive  shall resign for "Good  Reason",  as
       defined below, then, in such event:

6.4.1  Executive's Base Salary, as defined in Section 3 as then in effect, shall
       continue to be paid for a period of six (6) months ("Payment Period").

6.4.2  Company  shall  maintain  in effect  during the Payment  Period,  for the
       continued benefit of the Executive, all of the employee benefit plans and
       programs in which the Executive was entitled to  participate  immediately
       prior to the Executive's  termination provided same is possible under the
       general  terms  and  provisions  of  such  benefit  plans  and  programs.
       Moreover,  during  the  Payment  Period the  Company  shall  provide  the
       Executive with such reasonable  administrative  and  secretarial  support
       services as may be necessary or appropriate in order to assist  Executive
       in finding  new  employment  or  Executive  may  select an  out-placement
       service  to be paid  for by the  Company  at a cost  not to  exceed  Five
       Thousand Dollars ($5,000).

       For purposes of this Section 6.4, "Good Reason" shall mean:

       (i)    An assignment to the Executive of any duties inconsistent with, or
              a  material  change  in  the  nature  or  scope  of,   Executive's
              responsibilities, authority or duties hereunder.

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       (ii)   Failure  by the  Company  to comply  with the  provisions  of this
              Agreement.

       (iii)  Ill health of  Executive  or a member of his family,  or any other
              compelling  personal  circumstance which, in the mutual discretion
              of the  Executive,  and the  Chairman  of the  Company  makes  the
              Executive's   continued   employment  hereunder   impossible,   or
              inappropriate.

6.5    Executive may voluntarily  terminate his employment  under this Agreement
       without  Good  Reason,  as defined in  Section  6.4 above,  by giving the
       Company  ninety  (90) days prior  written  notice  thereof,  and upon the
       expiration of such ninety (90) day period,  Executive's  employment under
       this  Agreement  shall  terminate,  and  Company  shall  have no  further
       obligation  or  liabilities  under  this  Agreement  except  to  pay  the
       Executive the portion, if any, that remains unpaid of the Base Salary and
       unpaid  accrued  prorated  vacation  for  the  period  up to the  date of
       termination. Resignation as defined herein must be in written form to the
       Board, witnessed and signed by the Executive.

7.     Surrender of Books and Records.  Executive  acknowledges  that all lists,
       books,  records,  literature,  products and any other  materials owned by
       Company or its affiliates or used by them in connection  with the conduct
       of their business,  shall at all times remain the property of Company and
       its  affiliates  and  that  upon  termination  of  employment  hereunder,
       irrespective of the time, manner or cause of said termination,  Executive
       will  surrender  to Company and its  affiliates  all such  lists,  books,
       records, literature, products and other materials.

8.     Miscellaneous.

8.1    Any notice,  demand or  communication  required or  permitted  under this
       Agreement  shall be in writing  and shall be  sufficient  when  delivered
       personally,  or three (3) days after  mailing by  registered or certified
       mail,  return  receipt  requested,  or the next day if sent by nationally
       recognized overnight courier with proof of delivery, in each case postage
       prepaid, addressed as follows:

       If to the Company:
       AlphaRx Inc.
       75 East beaver Creek, Unit 10
       Richmond Hill, Ontario L4B 1B8
       Attn.: Michael M. Lee, President

       If to the Executive:
       Sai Ming Wong
       Room 1802, Choi Yuk House, Choi Yuen Estate
       Sheung Shui, Hong Kong

       The  foregoing  addressees  may be changed at any time by notice given in
the manner herein provided.

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<PAGE>

8.2    This Agreement constitutes the entire understanding and agreement between
       Company and Executive  regarding its subject  matter and  supersedes  all
       prior negotiations and agreements,  whether oral or written, between them
       with respect to its subject  matter.  This  Agreement may not be modified
       except by a written agreement signed by the Executive and the Company.

8.3    This  Agreement  shall be  binding  upon and inure to the  benefit of the
       parties and their respective  heirs,  executors,  successors and assigns,
       except that this Agreement may not be assigned by the Executive.

8.4    No waiver by either party of any  condition or of the breach by the other
       of any term or covenant  contained in this Agreement,  whether by conduct
       or otherwise,  in any one or more instances  shall be deemed or construed
       as a further or  continuing  waiver of any such  condition or breach or a
       waiver  of any  other  condition,  or the  breach  of any  other  term or
       covenant  set forth in this  Agreement.  Moreover,  the failure of either
       party to exercise any right  hereunder  shall not bar the later  exercise
       thereof.

8.5    This  Agreement  shall be governed by the statutes and common laws of the
       State of Delaware, excluding its choice of law statutes or common law.

8.6    The headings of the various  sections and  paragraphs  have been included
       herein for  convenience  only and shall not be construed in  interpreting
       this Agreement.

8.7    If  any   provision   of  this   Agreement   shall  be  held  invalid  or
       unenforceable,  the  remainder  of this  Agreement  shall,  nevertheless,
       remain in full force and  effect.  If any  provision  is held  invalid or
       unenforceable  with  respect  to  particular  circumstances,   it  shall,
       nevertheless, remain in full force and effect in all other circumstances.

8.8    This  Agreement  may be executed in several  counterparts,  each of which
       shall  be  deemed  to be an  original  but  all of  which  together  will
       constitute one and the same instrument.

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       IN WITNESS WHEREOF, this Agreement has been executed by the Executive and
on behalf of the Company by its duly authorized  officer on the date first above
written.

ALPHARX INC.

By:    /s/ Sandro Persia                   By:     /s/ Michael M. Lee
    -----------------------------              ---------------------------
       Sandro Persia                               Michael M. Lee
       Secretary                                   Chairman/CEO

EXECUTIVE

By:   /s/ Sai Ming Wong
    -----------------------------
          Sai Ming Wong

                                       8Exhibit 10.5(a)

                               AMENDMENT AGREEMENT

       AMENDMENT AGREEMENT, dated as of August 20, 2001, by and between ALPHARx,
INC.,  a  Delaware   corporation  (the  "Company"),   and  Sai  Ming  Wong  (the
"Executive").

                                    RECITALS

       The Company and the  Executive  are parties to an  Employment  Agreement,
dated July 1, 2000 (the  "Employment  Agreement"),  and have agreed to amend the
Employment  Agreement  to extend  the term of the  Employment  Agreement  and to
increase the Executive's compensation thereunder.  Capitalized terms used herein
shall have the meanings set forth in the Employment  Agreement  unless otherwise
defined herein.

       NOW,  THEREFORE,  in consideration of the mutual covenants and agreements
herein set forth, and for other good and valuable consideration, the receipt and
sufficiency of which are hereby acknowledged, the parties hereto hereby agree as
follows:

       1.  Section  1 of the  Employment  Agreement  is  hereby  deleted  in its
       entirety  and the  following  new  Section  1is hereby  inserted  in lieu
       thereof:

              1.  Employment  and Term.  Company  hereby  employs  Executive and
              Executive hereby accepts  employment for a term commencing on July
              1st, 2000 and continuing  until  December 31, 2003,  unless sooner
              terminated as provided for in this Agreement.

       2. Section 3.1.1 and 3.1.2 of the Employment  Agreement is hereby deleted
       in its entirety and the following  new Section 3.1 is hereby  inserted in
       lieu thereof.

              3.4    The Company  shall pay the  Executive an annual Base Salary
                     ("Base Salary") as follows:

                     (xvi)  commencing  July 1, 2000,  and ending  December  31,
                            2000, a Base Salary at the rate of $12,000 per year;

                     (xvii) commencing  January  1, 2001,  and  ending  June 30,
                            2001, a Base Salary at the rate of $36,000 per year;

                     (xviii)commencing  July 1, 2001,  and ending  December  31,
                            2001, a Base Salary at the rate of $72,000 per year;

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                     (xix)  commencing  January 1, 2002, and ending December 31,
                            2002, a Base Salary at the rate of $96,000 per year;
                            and

                     (xx)   commencing  January 1, 2003, and ending December 31,
                            2003,  a Base  Salary  at the rate of  $120,000  per
                            year.

                     The Executive's Base Salary shall be paid at such times and
              in such  manner as is  consistent  with the  Company's  prevailing
              payroll practices for other senior executives of the Company.

       3.  Except  as  otherwise  amended  by  this  Amendment  Agreement,   the
       Employment  Agreement  shall  remain in full  force and  effect,  and the
       Company and the Executive each hereby  reaffirm each of their  respective
       agreements, covenants and obligations set forth therein.

       IN WITNESS  WHEREOF,  the parties  hereto have  executed  this  Amendment
Agreement as of the date above written.

ALPHARX INC.

By:      /s/ Sandro Persia                   By:     /s/ Michael M. Lee
    ------------------------------              ---------------------------
         Sandro Persia                               Michael M. Lee
         Secretary                                   Chairman/CEO

EXECUTIVE

By:      /s/ Sai Ming Wong
    ------------------------------
             Sai Ming Wong

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                                   SIGNATURES:

       Pursuant to the requirements of Section 12 of the Securities Exchange Act
of 1934,  the  registrant has duly caused this report to be signed on its behalf
by the undersigned, thereunto duly authorized.

DATED: December 28, 2001

                                               ALPHARx, INC.

                                              By:    /S/ Michael M. Lee
                                                   -----------------------------
                                                   Michael M. Lee, President

                                              Directors:

                                                     /S/ Michael M. Lee
                                                   -----------------------------
                                                   Michael M. Lee, Director

                                                     /S/ Sai Ming Wong
                                                   -----------------------------
                                                   Sai Ming Wong, Director

                                                     /S/ Joseph Schwarz
                                                   -----------------------------
                                                   Joseph Schwarz, Director

                                                     /S/ Sandro Persia
                                                   -----------------------------
                                                   Sandro Persia, Director

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