Document:

EX-10.5

 Exhibit 10.5 
 CONSULTING AGREEMENT 
 (Robert S. Langer, Jr.) 

This Consulting Agreement dated as of October 31, 2006 (this “Agreement”), is made by and between BIND Biosciences,
Inc., a Delaware corporation (the “Company”), and Robert S. Langer, Jr. (the “Consultant”). 

WHEREAS, the Company and the Consultant desire to enter into a Consulting Agreement as provided herein (the
“Agreement”). 
 NOW, THEREFORE, in consideration of the premises and the mutual covenants set forth herein,
the parties hereby agree as follows: 
 1. Consulting Services. 

(a) The Company hereby retains the Consultant and the Consultant hereby agrees to perform such consulting and advisory services relating
to the Field of Interest (as defined in Section 13(j)) as the Company may request and as set forth in Schedule A (the “Consulting Services”). 
 (b) The Consultant agrees to make himself available to render the Consulting Services, at such times and locations as may be mutually agreed, from time to time as requested by the Company. Except as
provided in Schedule A, the Consultant may deliver the Consulting Services over the telephone, in person or by written correspondence. 
 (c) The Consultant agrees to devote his best efforts to performing the Consulting Services. The Consultant shall comply with all rules, procedures and standards promulgated from time to time by the
Company with regard to the Consultant’s access to and use of the Company’s property, information, equipment and facilities. 
 2. Compensation. The Company shall pay the Consultant a consulting fee as provided in Schedule A. The Company will reimburse the Consultant for reasonable business expenses incurred by the
Consultant in the performance of Consulting Services for the Company as provided in Schedule A. 
 3. Independent
Contractor. In furnishing the Consulting Services, the Consultant understands that he will at all times be acting as an independent contractor of the Company and, as such, will not be an employee of the Company and will not by reason of this
Agreement or by reason of his Consulting Services to the Company be entitled to participate in or to receive any benefit or right under any of the Company’s employee benefit or welfare plans. The Consultant also will be responsible for paying
all withholding and other taxes required by law to be paid as and when the same become due and payable. Consultant shall not enter into any agreements or incur any obligations on behalf of the Company. 

4. Term. The parties may terminate this Agreement with the mutual consent of both parties. The Company may terminate this
Agreement at any time for Cause (as defined in Section 13(j)) or at any time after April 30, 2010 without Cause; provided, however, that in the 

 
event this Agreement is terminated by the Company without Cause, then the Company shall (i) deposit into escrow with an escrow agent acceptable to both parties an amount of cash equal to the
consulting fee paid to the Consultant during the preceding ninety (90) days, and (ii) cause the escrow agent to pay such amount to the Consultant payable when and as if Consultant had continued to provide Consulting Services to the Company
during the ninety (90) days immediately following such termination. The Consultant may terminate this Agreement for any reason; provided, however, that he shall first provide written notice to the Company at least 30 days prior to the
effective date of termination. 
 5. Exceptions to this Agreement. 

(a) Certain Other Contracts. The Company acknowledges that (I) the Consultant is a member of the faculty of the Massachusetts
Institute of Technology (“M.I.T.”), and (II) the Consultant is now or may become a party to agreements with M.I.T. and other third parties relating to the disclosure of information, the ownership of inventions, restrictions against
competition and/or similar matters. The Consultant represents and agrees that the execution, delivery and performance of this Agreement does not and will not conflict with any other agreement, policy or rule applicable to the Consultant. The
Consultant will not (i) disclose to the Company any information that he is required to keep secret pursuant to an existing confidentiality agreement with M.I.T. or any other third party, (ii) use the funding, resources, facilities or
inventions of M.I.T. or any other third party to perform the Consulting Services, or (iii) perform the Consulting Services in any manner that would give M.I.T. or any other third party rights to any intellectual property created in connection
with such services. 
 (b) Prior Inventions. The Consultant has informed the Company, in writing, of any and all
inventions which he claims as his own or otherwise intends to exclude from this Agreement because it was developed by him prior to the date of this Agreement. The Consultant acknowledges that after execution of this Agreement he shall have no right
to exclude any Inventions (as defined in Section 7) from this Agreement. 
 6. Confidential Information. While
providing the Consulting Services to the Company and thereafter, the Consultant shall not, directly or indirectly, use any Confidential Information (as defined below) other than pursuant to his provision of the Consulting Services by and for the
benefit of the Company, or disclose to anyone outside of the Company any such Confidential Information. The term “Confidential Information” as used throughout this Agreement shall mean all trade secrets, proprietary information and
other data or information (and any tangible evidence, record or representation thereof), written or oral, whether prepared, conceived or developed by a consultant or employee of the Company (including the Consultant) or received by the Company from
an outside source, which is in the possession of the Company (whether or not the property of the Company) and which is maintained in secrecy or confidence by the Company. Without limiting the generality of the foregoing, Confidential Information
shall include: 
 (a) any idea, improvement, invention, innovation, development, concept, technical data, design, formula,
device, pattern, sequence, method, process, composition of matter, computer program or software, source code, object code, algorithm, model, diagram, flow chart, product specification or design, plan for a new or revised product, sample,

  
 - 2 -

 
compilation of information, or work in process, or parts thereof, and any and all revisions and improvements relating to any of the foregoing (in each case whether or not reduced to tangible
form); and 
 (b) the name of any customer, supplier, employee, prospective customer, sales agent, supplier or consultant, any
sales plan, marketing material, plan or survey, business plan or opportunity, product or development plan or specification, business proposal, financial record, or business record or other record or information relating to the present or proposed
business of the Company. 
 Notwithstanding the foregoing, the term Confidential Information shall not apply to information
which the Company has voluntarily disclosed to the public without restriction or which has otherwise lawfully entered the public domain. 
 The Consultant acknowledges that the Company from time to time has in its possession information (including product and development plans and specifications) which represent information which is claimed
by others to be proprietary and which the Company has agreed to keep confidential. The Consultant agrees that all such information shall be Confidential Information for purposes of this Agreement. 

The Consultant agrees that all originals and all copies of materials containing, representing, evidencing, recording, or constituting any
Confidential Information, however and whenever produced (whether by the Consultant or others), shall be the sole property of the Company. 
 7. Inventions. 
 (a) Certain Inventions Made by Others. Subject to
the Consultant’s obligations to M.I.T. and other third parties, during the Term of this Agreement, the Consultant will use his best efforts (i) to disclose to the President of the Company, on a confidential basis, technology and product
opportunities which come to the attention of the Consultant in the Field of Interest, and (ii) any invention, improvement, discovery, process, formula or method or other intellectual property relating to or useful in, the Field of Interest,
whether or not patentable or copyrightable, and whether or not discovered or developed by Consultant. 
 (b) Inventions Made
by the Consultant. Subject to the Consultant’s obligations to M.I.T., the Consultant agrees that all Confidential Information and all other discoveries, inventions, ideas, concepts, trademarks, service marks, logos, processes, products,
formulas, computer programs or software, source codes, object codes, algorithms, machines, apparatuses, items of manufacture or composition of matter, or any new uses therefor or improvements thereon, or any new designs or modifications or
configurations of any kind, or works of authorship of any kind, including, without limitation, compilations and derivative works, whether or not patentable or copyrightable, conceived, developed, reduced to practice or otherwise made by the
Consultant, either alone or with others, and in any way related to the Field of Interest or to tasks assigned to the Consultant during the course of his relationship with the Company, whether or not conceived, developed, reduced to practice or made
on the Company’s premises (collectively “Inventions”), and any and all services and products which embody, 

  
 - 3 -

 
emulate or employ any such Invention or Confidential Information shall be the sole property of the Company and all copyrights, patents, patent rights, trademarks and reproduction rights to, and
other proprietary rights in, each such Invention or Confidential Information, whether or not patentable or copyrightable, shall belong exclusively to the Company. The Consultant agrees that all such Inventions shall constitute works made for hire
under the copyright laws of the United States and hereby assigns and, to the extent any such assignment cannot be made at the present time, agrees to assign, to the Company any and all copyrights, patents and other proprietary rights he may have in
any such Invention, together with the right to file and/or own wholly without restrictions applications for United States and foreign patents, trademark registration and copyright registration and any patent, or trademark or copyright registration
issuing thereon. 
 8. Consultant’s Obligation to Keep Records. Consultant shall make and maintain adequate and
current written records of all Inventions, and shall disclose all Inventions promptly, fully and in writing to the Company immediately upon development of the same and at any time upon request. 

9. Consultant’s Obligation to Cooperate. The Consultant will, at any time during or after the term of this Agreement, upon
request of the Company, execute all documents and perform all lawful acts which the Company considers necessary or advisable to secure its rights hereunder and to carry out the intent of this Agreement. Without limiting the generality of the
foregoing, the Consultant will assist the Company in any reasonable manner to obtain for its own benefit patents or copyrights in any and all countries with respect to all Inventions assigned pursuant to Section 7, and the Consultant will
execute, when requested, patent and other applications and assignments thereof to the Company, or Persons (as defined in Section 13(j)) designated by it, and any other lawful documents deemed necessary by the Company to carry out the purposes
of this Agreement, and the Consultant will further assist the Company in every way to enforce any patents and copyrights obtained, including testifying in any suit or proceeding involving any of said patents or copyrights or executing any documents
deemed necessary by the Company, all without further consideration than provided for herein. It is understood that reasonable out-of-pocket expenses of the Consultant’s assistance incurred at the request of the Company under this Section will
be reimbursed by the Company. 
 10. Noncompetition. Subject to written waivers that may be provided by the Company upon
request, which shall not be unreasonably withheld, the Consultant agrees that during the term of this Agreement and for a period of one year after the termination of this Agreement, the Consultant shall not directly or indirectly (i) provide
any services in the Field of Interest to any Person other than the Company, (ii) become an owner, partner, shareholder, consultant, agent, employee or co-venturer of any Person that has committed, or intends to commit, significant resources to
the Field of Interest. Notwithstanding the foregoing, the Consultant may purchase as a passive investment up to one percent (1%) of any class or series of outstanding voting securities of any Person that has committed significant resources to
the Field of Interest if such class or series is listed on a national or regional securities exchange or publicly traded in the “over-the-counter” market. 
 11. Nonsolicitation. During the term of this Agreement and for a period of one year after the termination of this Agreement, the Consultant shall not (i) solicit, encourage, or take

  
 - 4 -

 
any other action which is intended to induce any employee of, or consultant to, the Company (or any other Person who may have been employed by, or may have been a consultant to, the Company
during the Term) to terminate his or her employment or relationship with the Company in order to become employed by or otherwise perform services for any other Person or (ii) solicit, endeavor to entice away from the Company or otherwise
interfere with the relationship of the Company with any Person who is, or was within the then-most recent 12 month period, a client or customer of the Company. 
 12. Return of Property. Upon termination of the Consultant’s engagement with the Company, or at any other time upon request of the Company, the Consultant shall return promptly any and all
Confidential Information, including customer or prospective customer lists, other customer or prospective customer information or related materials, computer programs, software, electronic data, specifications, drawings, blueprints, medical devices,
samples, reproductions, sketches, notes, notebooks, memoranda, reports, records, proposals, business plans, or copies of them, other documents or materials, tools, equipment, or other property belonging to the Company or its customers which the
Consultant may then possess or have under his control. The Consultant further agrees that upon termination of his engagement he shall not take with him any documents or data in any form or of any description containing or pertaining to Confidential
Information or any Inventions. 
 13. Miscellaneous. 

(a) Entire Agreement. This Agreement and the documents referred to herein constitute the entire agreement among the parties with
respect to the subject matter hereof and supersede all other prior agreements and understandings, both written and oral, between the parties with respect to such subject matter. 

(b) Assignment. This Agreement shall be binding upon and inure to the benefit of the parties hereto and their respective
successors and permitted assigns. This Agreement is not intended to confer upon any person other than the parties hereto any rights or remedies hereunder, except as otherwise expressly provided herein and shall not be assignable by operation of law
or otherwise. 
 (c) Amendments and Supplements. This Agreement may not be altered, changed or amended, except by an
instrument in writing signed by the parties hereto. 
 (d) No Waiver. The terms and conditions of this Agreement may be
waived only by a written instrument signed by the party waiving compliance. The failure of any party hereto to enforce at any time any of the provisions of this Agreement shall in no way be construed to be a waiver of any such provision, nor in any
way to affect the validity of this Agreement or any part hereof or the right of such party thereafter to enforce each and every such provision. No waiver of any breach of or non-compliance with this Agreement shall be held to be a waiver of any
other or subsequent breach or non-compliance. 
 (e) Governing Law. This Agreement shall be governed by, and construed
and enforced in accordance with, the substantive laws of The Commonwealth of Massachusetts, without regard to its principles of conflicts of laws. 

  
 - 5 -

 (f) Notice. All notices and other communications hereunder (other than Consulting
Services, which shall be delivered in the manner specified in Section 1 and Schedule A) shall be in writing and shall be deemed given if delivered by hand, sent by facsimile transmission with confirmation of receipt, sent via a reputable
overnight courier service with confirmation of receipt requested, or mailed by registered or certified mail (postage prepaid and return receipt requested) to the parties at the following addresses (or at such other address for a party as shall be
specified by like notice), and shall be deemed given on the date on which delivered by hand or otherwise on the date of receipt as confirmed: 
 To the Company: 
 BIND Biosciences, Inc. 

1000 Winter Street 
 Suite 3350 
 Waltham, MA 02451 

Attention: President 
 To the Consultant: 
 Robert S. Langer, Jr. 

98 Montvale Road 

Newton, MA 02459 

(g) Remedies. The Consultant recognizes that money damages alone would not adequately compensate the Company in the event of
breach by the Consultant of this Agreement, and the Consultant therefore agrees that, in addition to all other remedies available to the Company at law, in equity or otherwise, the Company shall be entitled to injunctive relief for the enforcement
hereof. All rights and remedies hereunder are cumulative and are in addition to and not exclusive of any other rights and remedies available at law, in equity, by agreement or otherwise. 

(h) Survival; Validity. Notwithstanding the termination of the Consultant’s relationship with the Company (whether pursuant
to Section 4 or otherwise), the Consultant’s covenants and obligations set forth in Sections 6, 7, 9, 10, 11, 12 and 13 shall remain in effect and be fully enforceable in accordance with the provisions thereof. In the event that any provision
of this Agreement shall be determined to be unenforceable by reason of its extension for too great a period of time or over too large a geographic area or over too great a range of activities, it shall be interpreted to extend only over the maximum
period of time, geographic area or range of activities as to which it may be enforceable. If, after application of the preceding sentence, any provision of this Agreement shall be determined to be invalid, illegal or otherwise unenforceable by a
court of competent jurisdiction, the validity, legality and enforceability of the other provisions of this Agreement shall not be affected thereby. Except as otherwise provided in this Section 13(h), any invalid, illegal or unenforceable
provision of this Agreement shall be severable, and after any such severance, all other provisions hereof shall remain in full force and effect. 

  
 - 6 -

 (i) Construction. A reference to a Section or a Schedule shall mean a Section in or
Schedule to this Agreement unless otherwise expressly stated. The titles and headings herein are for reference purposes only and shall not in any manner limit the construction of this Agreement which shall be considered as a whole. The words
“include,” “includes” and “including” when used herein shall be deemed in each case to be followed by the words “without limitation.” Whenever the context may require, any pronouns
used herein shall include the corresponding masculine, feminine or neuter forms, and the singular form of names and pronouns shall include the plural and vice-versa. 
 (j) Certain Definitions. 
 “Cause” shall mean:
(i) Consultant’s dishonesty with respect to the Company; (ii) Consultant’s misconduct which materially and adversely reflects upon the business, affairs, operations, or reputation of the Company or upon Consultant’s ability
to perform his duties for the Company; (iii) Consultant’s failure to perform his duties and responsibilities for the Company, which failure continues for more than ten (10) days after the Company gives written notice to Consultant
which sets forth in reasonable detail the nature of such failure; (iv) Consultant’s negligent performance of his duties, which negligent performance continues for more than ten (10) days after the Company gives written notice to
Consultant which sets forth in reasonable detail the nature of such negligence; or (v) Consultant’s breach of any one or more of the material provisions of this Agreement, which breach continues for more than ten (10) days after the
Company gives written notice to Consultant which sets forth in reasonable detail the nature of such breach. 
 “Field of
Interest” shall mean PEG-PLGA nanoparticles functionalized with macromolecules for human therapeutic applications. (For the avoidance of doubt, PEG is an abbreviation of polyethylene glycol and PLGA is an abbreviation for
polylactic-co-glycolic acid.) 
 “Person” shall mean an individual, a corporation, an association, a
partnership, an estate, a trust and any other entity or organization. 
 (k) Counterparts. This Agreement may be executed
in one or more counterparts, all of which together shall constitute one and the same Agreement. 
 ***** 

  
 - 7 -

 IN WITNESS WHEREOF, the parties have caused this Consulting Agreement to be executed as an
agreement under seal as of the date first written above. 
  

			
	BIND BIOSCIENCES, INC.
		
	By:	 	/s/ Paul D. Goldenheim
	Name:	 	Paul D. Goldenheim
	Title:	 	PRESIDENT
	
	CONSULTANT:
	
	 /s/ Robert S. Langer, Jr.

	Robert S. Langer, Jr.

  
 - 8 -

 Schedule A 

 

	 	1.	Description of Consulting Services. 

 The Consultant shall provide consulting services to the Company as may be mutually determined by the Company and Consultant from time to time. In determining the times and locations for the performance of
such services, due consideration shall be given to Consultant’s commitments to M.I.T. or any future employer of Consultant. 
  

	 	2.	Compensation. 

 2.1 The
Company shall pay Consultant a periodic consulting fee payable quarterly in arrears on the first day of February, May, August and November of each year during the term of this Agreement and all renewal terms of this Agreement. Such consulting fee
shall initially be $0.00, but shall increase upon the occurrence of the following events: (i) to $25,000 per 365-day period on and after the Initial Milestone Date (as defined below) and continuing until the Second Milestone Date (as defined
below); (ii) to $50,000 per 365-day period on and after the Second Milestone Date and continuing until the Third Milestone Date (as defined below); (iii) to $75,000 per 365-day period on and after the Third Milestone Date and continuing
until the Fourth Milestone Date (as defined below); and (iv) to $100,000 per 365-day period on and after the Fourth Milestone Date. 
 As used herein, the term “Initial Milestone Date” shall mean the date upon which the cumulative Cash Flow (as defined below) received by the Company shall be greater than $2,500,000; the
term “Second Milestone Date” shall mean the date upon which the cumulative Cash Flow received by the Company shall be greater than $10,000,000; the term “Third Milestone Date” shall mean the date upon which the
cumulative Cash Flow received by the Company shall be greater than $25,000,000; and the term “Fourth Milestone Date” shall mean the earliest to occur of (i) the date upon which the cumulative Cash Flow received by the Company
shall be greater than $50,000,000, (ii) the consummation by the Company of an Initial Public Offering (as defined below) or (iii) the sale of the Company in a merger or consolidation in which the Company is not the surviving corporation or
in which the Company is the surviving corporation but becomes a wholly-owned subsidiary of another corporation, or involving the sale of substantially all of the Company’s assets. 

The term “Cash Flow” shall include all funds received by the Company (other than funds which must be repaid), including,
without limitation, the proceeds of the sale of equity securities by the Company and the committed proceeds for equity and research funding in connection with a strategic alliance or corporate partnering transaction with a third party in the Field
of Interest. 
 The term “Initial Public Offering” shall mean a firm commitment underwritten public offering
pursuant to an effective registration statement under the Securities Act of 1933, as amended, covering the offer and sale of the Company’s Common Stock to the public, for the account of the Company, at a public offering price of at least $3.00
per share, with such amount to be appropriately adjusted to take account of any stock split, stock dividend, subdivision, combination of shares, or the like, and having an aggregate offering price to the public of not less than $30,000,000.

  
 - 9 -

 2.2 Consultant shall be reimbursed for all reasonable, appropriate or necessary travel and
other out-of-pocket expenses incurred in the performance of his duties hereunder upon submission and approval of written statements and bills in accordance with the then regular reimbursement procedures of the Company. 

  
 - 10 -

							
	

	  		  	 BIND Biosciences, Inc.
 64 Sidney Street
 Cambridge, MA 02139

 
	  	 www.bindbio.com
 p  617.491.3400
 f  617.491.0351

 

	  		  	  
	  		  	  

 June 11, 2010 
 Robert S. Langer, Jr. 
 98 Montvale Road 
 Newton, Massachusetts 02458 
  

	Re:	Modifications to Consulting Agreement 

Dear Bob: 
 The purpose of this
letter agreement (this “Amendment”) is to amend certain provisions to your consulting agreement with BIND Biosciences, Inc. (the “Company”) dated as of October 31, 2006 (your “Original Consulting
Agreement”). 
 Schedule A to your Original Consulting Agreement provides that your periodic consulting fee will
increase periodically upon the occurrence of certain triggering events. After discussion, we have agreed that the increase scheduled to occur at the Fourth Milestone Date, as defined in the Original Consulting Agreement, should take place as of
May 1, 2010. Accordingly, the defined term “Fourth Milestone Date” is hereby amended as follows: 
 The term
“Fourth Milestone Date” shall mean May 1, 2010. 
 Further, we have agreed that the increase scheduled to
take place on the Fourth Milestone Date, as defined herein, will raise your periodic consulting fee to an annual rate of $125,000. Therefore, Section 2.1(iv) of Schedule A to your Original Consulting Agreement is hereby amended to read as
follows: 
 (iv) to $125,000 per 365-day period on and after the Fourth Milestone Date. 

Except as expressly amended by this Amendment, your Original Consulting Agreement remains in full force and affect and otherwise
unchanged. The Original Consulting Agreement shall, together with this Amendment, be read and construed as a single document. Please indicate your agreement to the Amendment by signing below. 

 

			
	Very truly yours,
	
	BIND BIOSCIENCES, INC.
		
	By:	 	 /s/ Scott Minick

		 	Scott Minick
		 	President and Chief Executive Officer

  

	
	Acknowledged and agreed by:
	
	 /s/ Robert S. Langer, Jr.

	 Robert S. Langer, Jr.EX-10.6

 Exhibit 10.6 
 AMENDED AND RESTATED CONSULTING AGREEMENT 
 (Omid Farokhzad) 

This Amended and Restated Consulting Agreement dated as of July 12, 2007 (this “Agreement”), is made by and between BIND
Biosciences, Inc., a Delaware corporation (the “Company”), and Omid Farokhzad (the “Consultant”). 
 WHEREAS, the Company and the Consultant are parties to a Consulting Agreement dated as of October 31, 2006 (the “Original Agreement”); and 

WHEREAS, the Company and the Consultant desire to amend and restate the Original Agreement as provided herein; 

NOW, THEREFORE, in consideration of the premises and the mutual covenants set forth herein, the parties hereby agree as follows:

 1. Consulting Services. 
 (a) The Company hereby retains the Consultant and the Consultant hereby agrees to perform such consulting and advisory services relating to the Field of Interest (as defined in Section 13G)) as the
Company may request and as set forth in Schedule A (the “Consulting Services”). 
 (b) The Consultant
agrees to make himself available to render the Consulting Services, at such times and locations as may be mutually agreed, from time to time as requested by the Company. Except as provided in Schedule A, the Consultant may deliver the
Consulting Services over the telephone, in person or by written correspondence. 
 (c) The Consultant agrees to devote his best
efforts to performing the Consulting Services. The Consultant shall comply with all rules, procedures and standards promulgated from time to time by the Company with regard to the Consultant’s access to and use of the Company’s property,
information, equipment and facilities. 
 (d) The Company acknowledges that (i) the Consultant is a member of the faculty
of Harvard Medical School (“Harvard”); (ii) the Consultant is subject to certain policies of Harvard, as such policies may be revised from time to time, including among others, policies concerning consulting, conflicts of
interest and commitment, intellectual property, and use of Harvard’s name; and (iii) any provision of this Agreement that conflicts with such policies shall be superseded by such policies. Further, the Company agrees that this Agreement is
subject to the Addendum attached hereto, the terms of which are incorporated herein by reference. 
 2.
Compensation. The Company shall pay the Consultant a consulting fee as provided in Schedule A. The Company will reimburse the Consultant for reasonable business expenses incurred by the Consultant in the performance of Consulting
Services for the Company as provided in Schedule A. 

 3. Independent Contractor. In furnishing the Consulting Services, the Consultant
understands that he will at all times be acting as an independent contractor of the Company and, as such, will not be an employee of the Company and will not by reason of this Agreement or by reason of his Consulting Services to the Company be
entitled to participate in or to receive any benefit or right under any of the Company’s employee benefit or welfare plans. The Consultant also will be responsible for paying all withholding and other taxes required by law to be paid as and
when the same become due and payable. Consultant shall not enter into any agreements or incur any obligations on behalf of the Company. 
 4. Term. The parties may terminate this Agreement with the mutual consent of both parties. The Company may terminate this Agreement at any time for Cause (as defined in Section 13U)) or at any
time after April 30, 2010 without Cause; provided, however, that in the event this Agreement is terminated by the Company without Cause, then the Company shall (i) deposit into escrow with an escrow agent acceptable to both parties
an amount of cash equal to the consulting fee paid to the Consultant during the preceding ninety (90) days, and (ii) cause the escrow agent to pay such amount to the Consultant payable when and as if Consultant had continued to provide
Consulting Services to the Company during the ninety (90) days immediately following such termination. The Consultant may terminate this Agreement for any reason; provided, however, that he shall first provide written notice to the
Company at least 30 days prior to the effective date of termination. 
 5. Exceptions to this Agreement. 

(a) Certain Other Contracts and Obligations. The Company acknowledges that (I) the Consultant is a member of the faculty of
Harvard and a member of the staff of The Brigham and Women’s Hospital (“Brigham”), and (II) the Consultant is now or may become a party to agreements with Harvard and/or Brigham and other third parties relating to the
disclosure of proprietary information, the ownership of discoveries and inventions, restrictions against competition and/or similar matters. The Consultant represents and agrees that the execution, delivery and performance of this Agreement does not
and will not conflict with any other agreement, policy or rule applicable to the Consultant. The Consultant will not (i) disclose to the Company any information that he is required to keep secret pursuant to an existing confidentiality
agreement with Harvard, Brigham or any other third party, (ii) use the funding, resources, facilities or inventions of Harvard, Brigham or any other third party to perform the Consulting Services, or (iii) perform the Consulting Services
in any manner that would give Harvard, Brigham or any other third party rights to any intellectual property created in connection with such Consulting Services. 
 (b) Prior Inventions. The Consultant has informed the Company, in writing, of any and all inventions which he claims as his own or otherwise intends to exclude from this Agreement because it was
developed by him prior to the date of this Agreement. The Consultant acknowledges that after execution of this Agreement he shall have no right to exclude any Company Inventions (as defined in Section 7) from this Agreement. The provisions of
this Section 5(b) shall not apply to, and the definition of Company Inventions in Section 7 shall not be understood to include, any invention or other form of intellectual property made or developed by the Consultant in connection with his
activities as a faculty member of Harvard or that are otherwise subject to the intellectual property policies of Harvard. 

  
 - 2 -

 6. Confidential Information. While providing the Consulting Services to the Company
and thereafter, the Consultant shall not, directly or indirectly, use any Confidential Information (as defined below) other than pursuant to his provision of the Consulting Services by and for the benefit of the Company, or disclose to anyone
outside of the Company any such Confidential Information. The term “Confidential Information” as used throughout this Agreement shall mean all trade secrets, proprietary information and other data or information (and any tangible
evidence, record or representation thereof), written or oral, whether prepared, conceived or developed by a consultant or employee of the Company (including the Consultant) or received by the Company from an outside source, which is in the
possession of the Company (whether or not the property of the Company) and which is maintained in secrecy or confidence by the Company. Without limiting the generality of the foregoing, Confidential Information shall include: 

(a) any idea, improvement, invention, innovation, development, concept, technical data, design, formula, device, pattern, sequence,
method, process, composition of matter, computer program or software, source code, object code, algorithm, model, diagram, flow chart, product specification or design, plan for a new or revised product, sample, compilation of information, or work in
process, or parts thereof, and any and all revisions and improvements relating to any of the foregoing (in each case whether or not reduced to tangible form); and 
 (b) the name of any customer, supplier, employee, prospective customer, sales agent, supplier or consultant, any sales plan, marketing material, plan or survey, business plan or opportunity, product or
development plan or specification, business proposal, financial record, or business record or other record or information relating to the present or proposed business of the Company. 

Notwithstanding the foregoing, the term Confidential Information shall not apply to information which (i) the Company has
voluntarily disclosed to the public without restriction or which has otherwise lawfully entered the public domain; (ii) was already properly and lawfully in the Consultant’s possession at the time it was received from the Company, as
evidenced by the Consultant’s written records; (iii) was or is lawfully received by the Consultant from a third party who was under no obligation of confidentiality respect thereto; (iv) was or is independently developed by Consultant
without reference to Company Confidential Information, as evidenced by the Consultant’s written records; or (v) is required to be disclosed by law, regulation or judicial or administrative process. 

The Consultant acknowledges that the Company from time to time has in its possession information (including product and development plans
and specifications) which is claimed by others to be proprietary and which the Company has agreed to keep confidential. The Consultant agrees that all such information shall be Confidential Information for purposes of this Agreement. 

The Consultant agrees that all originals and all copies of materials containing, representing, evidencing, recording, or constituting any
Confidential Information, however and whenever produced (whether by the Consultant or others), shall be the sole property of the Company. 

  
 - 3 -

 7. Inventions. Subject to the Consultant’s obligations to Harvard and Brigham,
the Consultant agrees that all Confidential Information and all other discoveries, inventions, ideas, concepts, trademarks, service marks, logos, processes, products, formulas, computer programs or software, source codes, object codes, algorithms,
machines, apparatuses, items of manufacture or composition of matter, or any new uses therefor or improvements thereon, or any new designs or modifications or configurations of any kind, or works of authorship of any kind, including, without
limitation, compilations and derivative works, whether or not patentable or copyrightable, conceived, developed, reduced to practice or otherwise made by the Consultant, either alone or with others, and in any way related to the Field of Interest or
to tasks assigned to the Consultant during the course of his relationship with the Company, whether or not conceived, developed, reduced to practice or made on the Company’s premises (collectively “Company Inventions”), and any
and all services and products which embody, emulate or employ any such Company Invention or Confidential Information shall be the sole property of the Company and all copyrights, patents, patent rights, trademarks and reproduction rights to, and
other proprietary rights in, each such Company Invention or Confidential Information, whether or not patentable or copyrightable, shall belong exclusively to the Company. The Consultant agrees that all such Company Inventions shall constitute works
made for hire under the copyright laws of the United States and hereby assigns and, to the extent any such assignment cannot be made at the present time, agrees to assign, to the Company any and all copyrights, patents and other proprietary rights
he may have in any such Company Invention, together with the right to file and/or own wholly without restrictions applications for United States and foreign patents, trademark registration and copyright registration and any patent, or trademark or
copyright registration issuing thereon. 
 8. Consultant’s Obligation to Keep Records. Consultant shall make and
maintain adequate and current written records of all Company Inventions, and shall disclose all Company Inventions promptly, fully and in writing to the Company immediately upon development of the same and at any time upon request. 

9. Consultant’s Obligation to Cooperate. The Consultant will, at any time during or after the term of this Agreement, upon
request of the Company, execute all documents and perform all lawful acts which the Company considers necessary or advisable to secure its rights hereunder and to carry out the intent of this Agreement. Without limiting the generality of the
foregoing, the Consultant will assist the Company in any reasonable manner to obtain for its own benefit patents or copyrights in any and all countries with respect to all Company Inventions assigned pursuant to Section 7, and the Consultant
will execute, when requested, patent and other applications and assignments thereof to the Company, or Persons (as defined in Section 13U)) designated by it, and any other lawful documents deemed necessary by the Company to carry out the
purposes of this Agreement, and the Consultant will further assist the Company in every way to enforce any patents and copyrights obtained, including testifying in any suit or proceeding involving any of said patents or copyrights or executing any
documents deemed necessary by the Company, all without further consideration than provided for herein. It is understood that reasonable out-of-pocket expenses of the Consultant’s assistance incurred at the request of the Company under this
Section will be reimbursed by the Company. 
 10. Noncompetition. Subject to written waivers that may be provided by the
Company upon request, which shall not be unreasonably withheld, the Consultant agrees that 

  
 - 4 -

 
during the term of this Agreement and for a period of one year after the termination of this Agreement, the Consultant shall not directly or indirectly (i) provide any services in the Field
of Interest to any Person other than the Company, (ii) become an owner, partner, shareholder, consultant, agent, employee or co-venturer of any Person that has committed, or intends to commit, significant resources to the Field of Interest.
Notwithstanding the foregoing, the Consultant may purchase as a passive investment up to one percent (1%) of any class or series of outstanding voting securities of any Person that has committed significant resources to the Field of Interest if such
class or series is listed on a national or regional securities exchange or publicly traded in the “over-the-counter” market. 
 11. Nonsolicitation. During the term of this Agreement and for a period of one year after the termination of this Agreement, the Consultant shall not (i) solicit, encourage, or take any other
action which is intended to induce any employee of, or consultant to, the Company (or any other Person who may have been employed by, or may have been a consultant to, the Company during the term of this Agreement) to terminate his or her employment
or relationship with the Company in order to become employed by or otherwise perform services for any other Person or (ii) solicit, endeavor to entice away from the Company or otherwise interfere with the relationship of the Company with any
Person who is, or was within the then-most recent 12 month period, a client or customer of the Company. 
 12. Return of
Property. Upon termination of the Consultant’s engagement with the Company, or at any other time upon request of the Company, the Consultant shall return promptly any and all Confidential Information, including customer or prospective
customer lists, other customer or prospective customer information or related materials, computer programs, software, electronic data, specifications, drawings, blueprints, medical devices, samples, reproductions, sketches, notes, notebooks,
memoranda, reports, records, proposals, business plans, or copies of them, other documents or materials, tools, equipment, or other property belonging to the Company or its customers which the Consultant may then possess or have under his control.
The Consultant further agrees that upon termination of his engagement he shall not take with him any documents or data in any form or of any description containing or pertaining to Confidential Information or any Company Inventions. 

13. Miscellaneous. 
 (a) Entire Agreement. This Agreement and the documents referred to herein constitute the entire agreement among the parties with respect to the subject matter hereof and supersede all other prior
agreements and understandings, both written and oral, between the parties with respect to such subject matter. 
 (b)
Assignment. This Agreement shall be binding upon and inure to the benefit of the parties hereto and their respective successors and permitted assigns. This Agreement is not intended to confer upon any person other than the parties hereto any
rights or remedies hereunder, except as otherwise expressly provided herein and shall not be assignable by operation of law or otherwise. 
 (c) Amendments and Supplements. This Agreement may not be altered, changed or amended, except by an instrument in writing signed by the parties hereto. 

  
 - 5 -

 (d) No Waiver. The terms and conditions of this Agreement may be waived only by a
written instrument signed by the party waiving compliance. The failure of any party hereto to enforce at any time any of the provisions of this Agreement shall in no way be construed to be a waiver of any such provision, nor in any way to affect the
validity of this Agreement or any part hereof or the right of such party thereafter to enforce each and every such provision. No waiver of any breach of or non-compliance with this Agreement shall be held to be a waiver of any other or subsequent
breach or non-compliance. 
 (e) Governing Law; Jurisdiction. This Agreement shall be governed by, and construed and
enforced in accordance with, the substantive laws of The Commonwealth of Massachusetts, without regard to its principles of conflicts of laws. All litigation arising from or relating to this Agreement shall be filed in, prosecuted before, and
resolved by any court of competent subject matter jurisdiction in Boston, Massachusetts. The Consultant consents to the jurisdiction of the courts located in Boston, Massachusetts over him, stipulates to the convenience, efficiency and fairness of
proceeding in such courts, and covenants not to allege or assert the inconvenience, inefficiency or unfairness of proceeding in such courts. 
 (f) Notice. All notices and other communications hereunder (other than Consulting Services, which shall be delivered in the manner specified in Section 1 and Schedule A) shall be in
writing and shall be deemed given if delivered by hand, sent by facsimile transmission with confirmation of receipt, sent via a reputable overnight courier service with confirmation of receipt requested, or mailed by registered or certified mail
(postage prepaid and return receipt requested) to the parties at the following addresses (or at such other address for a party as shall be specified by like notice), and shall be deemed given on the date on which delivered by hand or otherwise on
the date of receipt as confirmed: 
 To the Company: 
 BIND Biosciences, Inc. 
 1000 Winter Street 

Suite 3350 

Waltham, MA 02451 

Attention: President 
 To the Consultant: 
 Omid Farokhzad 

490 Beacon Street 

Chestnut Hill, MA 02476 
 (g) Remedies. The Consultant recognizes that money damages alone would not adequately compensate the Company in the event of breach by the Consultant of this Agreement, and the Consultant therefore
agrees that, in addition to all other remedies available to the Company at law, in equity or otherwise, the Company shall be entitled to injunctive relief for the enforcement hereof. All rights and remedies hereunder are cumulative and are in
addition to and not exclusive of any other rights and remedies available at law, in equity, by agreement or otherwise. 

  
 - 6 -

 (h) Survival; Validity. Notwithstanding the termination of the Consultant’s
relationship with the Company (whether pursuant to Section 4 or otherwise), the Consultant’s covenants and obligations set forth in Sections 6, 7, 9, 10, 11, 12 and 13 shall remain in effect and be fully enforceable in accordance with the
provisions thereof. In the event that any provision of this Agreement shall be determined to be unenforceable by reason of its extension for too great a period of time or over too large a geographic area or over too great a range of activities, it
shall be interpreted to extend only over the maximum period of time, geographic area or range of activities as to which it may be enforceable. If, after application of the preceding sentence, any provision of this Agreement shall be determined to be
invalid, illegal or otherwise unenforceable by a court of competent jurisdiction, the validity, legality and enforceability of the other provisions of this Agreement shall not be affected thereby. Except as otherwise provided in this
Section 13(h), any invalid, illegal or unenforceable provision of this Agreement shall be severable, and after any such severance, all other provisions hereof shall remain in full force and effect. 

(i) Construction. A reference to a Section or a Schedule shall mean a Section in or Schedule to this Agreement unless otherwise
expressly stated. The titles and headings herein are for reference purposes only and shall not in any manner limit the construction of this Agreement which shall be considered as a whole. The words “include,”
“includes” and “including” when used herein shall be deemed in each case to be followed by the words “without limitation.” Whenever the context may require, any pronouns used herein shall include
the corresponding masculine, feminine or neuter forms, and the singular form of names and pronouns shall include the plural and vice-versa. 
 (j) Certain Definitions. 
 “Cause” shall mean:
(i) Consultant’s dishonesty with respect to the Company; (ii) Consultant’s misconduct which materially and adversely reflects upon the business, affairs, operations, or reputation of the Company or upon Consultant’s ability
to perform his duties for the Company; (iii) Consultant’s failure to perform his duties and responsibilities for the Company, which failure continues for more than ten (1 0) days after the Company gives written notice to Consultant which
sets forth in reasonable detail the nature of such failure; (iv) Consultant’s negligent performance of his duties, which negligent performance continues for more than ten (1 0) days after the Company gives written notice to Consultant
which sets forth in reasonable detail the nature of such negligence; or (v) Consultant’s breach of any one or more of the material provisions of this Agreement, which breach continues for more than ten (1 0) days after the Company gives
written notice to Consultant which sets forth in reasonable detail the nature of such breach. 
 “Field of
Interest” shall mean PEG-PLGA nanoparticles functionalized with macromolecules for human therapeutic applications. (For the avoidance of doubt, PEG is an abbreviation of polyethylene glycol and PLGA is an abbreviation for poly
lactic-co-glycolic acid.) 

  
 - 7 -

 “Person” shall mean an individual, a corporation, an association, a
partnership, an estate, a trust and any other entity or organization. 
 (k) Counterparts. This Agreement may be executed
in one or more counterparts, all of which together shall constitute one and the same Agreement. Facsimile transmission of execution copies or signature pages for this Agreement shall be legal, valid and binding execution and delivery for all
purposes. 
 ***** 

  
 - 8 -

 IN WITNESS WHEREOF, the parties have caused this Consulting Agreement to be executed as an
agreement under seal as of the date first written above. 
  

			
	BIND BIOSCIENCES, INC.
		
	By :	 	/s/ Glenn Batchelder
	Name:	 	CEO
	Title:	 	Glenn Batchelder
	
	CONSULTANT:
	
	/s/ Omid Farokhzad
	Omid Farokhzad

  
 - 9 -

 Schedule A 
 1. Description of Consulting Services. 
 The Consultant shall provide
consulting services to the Company as may be mutually determined by the Company and Consultant from time to time. In determining the times and locations for the performance of such services, due consideration shall be given to Consultant’s
commitments to Harvard, Brigham or any future employer of Consultant. 
 2. Compensation. 

2.1 The Company shall pay Consultant a periodic consulting fee payable quarterly in arrears on the first day of February, May, August and
November of each year during the term of this Agreement and all renewal terms of this Agreement. Such consulting fee shall initially be $0.00, but shall increase upon the occurrence of the following events: (i) to $25,000 per 365-day period on
and after the Initial Milestone Date (as defined below) and continuing until the Second Milestone Date (as defined below); (ii) to $50,000 per 365-day period on and after the Second Milestone Date and continuing until the Third Milestone Date
(as defined below); (iii) to $75,000 per 365-day period on and after the Third Milestone Date and continuing until the Fourth Milestone Date (as defined below); and (iv) to $100,000 per 365-day period on and after the Fourth Milestone
Date. 
 As used herein, the term “Initial Milestone Date” shall mean the date upon which the cumulative Cash
Flow (as defined below) received by the Company shall be greater than $2,500,000; the term “Second Milestone Date” shall mean the date upon which the cumulative Cash Flow received by the Company shall be greater than $10,000,000;
the term “Third Milestone Date” shall mean the date upon which the cumulative Cash Flow received by the Company shall be greater than $25,000,000; and the term “Fourth Milestone Date” shall mean the earliest to
occur of (i) the date upon which the cumulative Cash Flow received by the Company shall be greater than $50,000,000, (ii) the consummation by the Company of an Initial Public Offering (as defined below) or (iii) the sale of the
Company in a merger or consolidation in which the Company is not the surviving corporation or in which the Company is the surviving corporation but becomes a wholly-owned subsidiary of another corporation, or involving the sale of substantially all
of the Company’s assets. 
 The term “Cash Flow” shall include all funds received by the Company (other
than funds which must be repaid), including, without limitation, the proceeds of the sale of equity securities by the Company and the committed proceeds for equity and research funding in connection with a strategic alliance or corporate partnering
transaction with a third party in the Field of Interest. 
 The term “Initial Public Offering” shall mean a
firm commitment underwritten public offering pursuant to an effective registration statement under the Securities Act of 1933, as amended, covering the offer and sale of the Company’s Common Stock to the public, for the account of the Company,
at a public offering price of at least $3.00 per share, with such amount to be appropriately adjusted to take account of any stock split, stock dividend, subdivision, combination of shares, or the like, and having an aggregate offering price to the
public of not less than $30,000,000. 

  
 - 10 -

 2.2 Consultant shall be reimbursed for all reasonable, appropriate or necessary travel and
other out-of-pocket expenses incurred in the performance of his duties hereunder upon submission and approval of written statements and bills in accordance with the then regular reimbursement procedures of the Company. 

  
 - 11 -

 Addendum to Consulting Agreement 

The Company acknowledges that Consultant’s primary employment responsibility is to Harvard Medical School and Harvard University
(together, “HMS”) and that Consultant’s obligations under HMS policies take priority over any obligations that Consultant may have to the Company by reason of this Agreement. 

The Company acknowledges that Consultant’s activities may be further bound by the policies of Governmental agencies (e.g. the
National Institutes of Health) or funding agencies (e.g., the Howard Hughes Medical Institute or the Juvenile Diabetes Foundation) as applicable, including policies relating to consulting and conflicts of interest, and that such policies may take
priority over any obligations that Consultant may have to the Company by reason of this Agreement. 
 The parties understand and
agree that it is Consultant’s responsibility to ensure that Consultant’s services to the Company do not employ proprietary information of HMS nor make substantial use of HMS’s time or resources nor involve HMS students, employees,
post-doctoral trainees or any other HMS personnel other than the Consultant. 
 Subject to obligations to protect the
Company’s proprietary or confidential information, Consultant’s services may not restrict or hinder his/her ability to conduct current or foreseeable research or teaching assignments with HMS, nor limit Consultant’s ability to publish
work generated at or on the behalf of HMS, nor infringe on Consultant’s academic freedom. 
 The Company will have no
rights by reason of the Agreement in any intellectual property whatsoever, whether or not patentable or copyrightable, generated wholly or in part as a result of Consultant’s activities as an employee of HMS or using the resources or
proprietary information of HMS. 
 The Company further acknowledges that Consultant will serve as a consultant in the capacity
of an individual, and not as an agent, employee or representative of HMS. Any confidential or other information provided to Consultant by Company will be deemed received only by Consultant as an individual and not by HMS, and any obligations
pertaining thereto will apply only to the Consultant and not HMS. 
 The name of HMS or Harvard or its affiliates may not be
used in connection with Consultant’s services, other than in affiliation as his employer, without written permission from HMS. 
  

									
	BIND Biosciences, Inc.	 		 	CONSULTANT
				
	By:	 	 /s/ Glenn Batchelder
	 		 	 /s/ Omid Farokhzad

	Name:	 	Glenn Batchelder	 		 	Omid Farokhzad
	Title:	 	CEO	 		 		 	
	Date:	 	7/12, 2007	 		 	Date:	 	7/12/07, 2007

					
	

	  	BIND Biosciences, Inc.	  	www.bindbio.com
		  	64 Sidney Street	  	p 617.491.3400
		  	Cambridge, MA 02139	  	f 617.491.0351

 June 11, 2010 
 Omid Farokhzad 
 490 Beacon Street 
 Chestnut Hill, Massachusetts 03476 
  

	Re:	Modifications to Consulting Agreement 

Dear Omid: 
 The purpose of
this letter agreement (this “Amendment”) is to amend certain provisions to your consulting agreement with BIND Biosciences, Inc. (the “Company”) dated as of October 31, 2006 (your “Original Consulting
Agreement”). 
 Schedule A to your Original Consulting Agreement provides that your periodic consulting fee will
increase periodically upon the occurrence of certain triggering events. After discussion, we have agreed that the increase scheduled to occur at the Fourth Milestone Date, as defined in the Original Consulting Agreement, should take place as of
today’s date. Accordingly, the defined term “Fourth Milestone Date” is hereby amended as follows: 
 The term
“Fourth Milestone Date” shall mean June 11, 2010. 
 Except as expressly amended by this Amendment, your
Original Consulting Agreement remains in full force and affect and otherwise unchanged. The Original Consulting Agreement shall, together with this Amendment, be read and construed as a single document. Please indicate your agreement to the
Amendment by signing below. 
  

			
	Very truly yours,
	
	BIND BIOSCIENCES, INC.
		
	By:	 	/s/ Scott Minick
		 	  
 Scott
Minick

		 	President and Chief Executive Officer

  

	
	Acknowledged and agreed by:
	
	 /s/ Omid Farokhzad

	Omid Farokhzad

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00220-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00220-of-00352.parquet"}]]