Document:

edit_Ex10_1

		
			Exhibit 10.1
		

		
			EDITAS MEDICINE, INC.
		

		
			Restricted Stock Agreement
		

		
			2015 Stock Incentive Plan
		

		
			This Restricted Stock Agreement (this “Agreement”) is made as of the Grant Date set forth below between Editas Medicine, Inc., a Delaware corporation (the “Company”), and the Participant named below.
		

		
			NOTICE OF GRANT
		

			
					
						 

					
					
						 

				
	
					
						Name of Participant (the “Participant”):

					
					
						 

				
	
					
						Grant Date:

					
					
						 

				
	
					
						Number of shares of the restricted common stock, $0.0001 par value per share (the “Common Stock”) awarded (“Restricted Shares”):

					
					
						 

				
	
					
						Vesting Start Date:

					
					
						 

				

		
			 
		

		
			Vesting Schedule:
		

			
					
						 

					
					
						 

				
	
					
						Vesting Date

					
					
						Number of Shares that Vest

				
	
					
						 

					
					
						 

				
	
					
						Except as provided herein, all vesting is dependent on the Participant remaining an Eligible Participant on each applicable Vesting Date.

				

		
			 
		

		
			This Agreement includes this Notice of Grant and the following Exhibit and the 2015 Stock Incentive Plan (the “Plan”),  each of which is expressly incorporated by reference in their entirety herein:
		

		
			Exhibit A – General Terms and Conditions
		

		
			The undersigned participant acknowledges that he has received a copy of the Plan.
		

		
			Please confirm your acceptance of this restricted stock award and of the terms and conditions of this Agreement by signing a copy of this Agreement where indicated below.
		

			
					
						 

					
					
						 

					
					
						 

					
					
						 

					
					
						 

				
	
					
						EDITAS MEDICINE, INC.

					
					
						 

					
					
						PARTICIPANT

					
					
						 

				
	
					
						By:

					
					
						 

					
					
						 

					
					
						 

					
					
						 

				
	
					
						 

					
					
						Name:

					
					
						 

					
					
						Name:

					
					
						 

				
	
					
						 

					
					
						Title:

					
					
						 

					
					
						Address:

					
					
						 

				

		
			 
		

		
			
		

		
			

		 

		

			1

		

 

		

		
			Restricted Stock Agreement
		

		
			2015 Stock Incentive Plan
		

		
			EXHIBIT A
		

		
			GENERAL TERMS AND CONDITIONS
		

		
			The terms and conditions of the award of Restricted Shares made to the Participant, as set forth in the Notice of Grant that forms part of this Agreement (the “Notice of Grant”), are as follows:
		

			
	
			
				 1.
			Issuance of Restricted Shares.

			
	
			
				 (a)
			The Restricted Shares are issued to the Participant, effective as of the Grant Date (as set forth on the Notice of Grant), in consideration of services rendered and to be rendered by the Participant to the Company.

			
	
			
				 (b)
			The Restricted Shares will initially be issued by the Company in book entry form only, in the name of the Participant.  Following the vesting of any Restricted Shares pursuant to Section 2 below, the Company shall, if requested by the Participant, issue and deliver to the Participant a certificate representing the vested Restricted Shares.  The Participant agrees that the Restricted Shares shall be subject to the forfeiture provisions set forth in Section 3 of this Agreement and the restrictions on transfer set forth in Section 4 of this Agreement.

			
	
			
				 2.
			Vesting Schedule.  The Restricted Shares shall vest in accordance with Vesting Schedule set forth in the Notice of Grant (the “Vesting Schedule”).  Any fractional number of Restricted Shares resulting from the application of the percentages in the Vesting Schedule shall be rounded down to the nearest whole number of Restricted Shares.

			
	
			
				 3.
			Forfeiture of Unvested Restricted Shares Upon Employment Termination.  In the event that the Participant ceases to be an Eligible Participant for any reason or no reason, with or without cause, all of the Restricted Shares that are unvested as of the time of such cessation shall be forfeited immediately and automatically to the Company, without the payment of any consideration to the Participant, effective as of such cessation. The Participant shall have no further rights with respect to any Restricted Shares that are so forfeited.  The Participant shall be an “Eligible Participant” if he or she is an employee, director or officer of, or consultant or advisor to, the Company or any other entity the employees, officers, directors, consultants or advisors of which are eligible to receive awards of restricted stock under the Plan.

			
	
			
				 4.
			Restrictions on Transfer.  The Participant shall not sell, assign, transfer, pledge, hypothecate or otherwise encumber, by operation of law or otherwise (collectively “transfer”) any Restricted Shares, or any interest therein, until such Restricted Shares have vested, except that the Participant may transfer such Restricted Shares to or for the benefit of any immediate family member, family trust or other entity established for the benefit of the Participant and/or an immediate family member thereof if the Company would be eligible to use a Form S‐8 under the Securities Act of 1933, as amended (the “Securities Act”) for the registration of the sale of the Restricted Shares to such proposed transferee, provided that the Company shall not be required to recognize any such permitted transfer until such time as such permitted transferee shall, as a 

		 

		

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	condition to the transfer, deliver to the Company a written instrument in form and substance satisfactory to the Company confirming that such transferee shall be bound by all of the terms and conditions of this Agreement.  The Company shall not be required to (i) transfer on its books any of the Restricted Shares which have been transferred in violation of any of the provisions of this Agreement or (ii) treat as owner of such Restricted Shares or to pay dividends to any transferee to whom such Restricted Shares have been transferred in violation of any of the provisions of this Agreement.

			
	
			
				 5.
			Restrictive Legends.  The book entry account reflecting the issuance of the Restricted Shares in the name of the Participant shall bear a legend or other notation upon substantially the following terms:

		
			“THE SHARES REPRESENTED BY THIS CERTIFICATE ARE SUBJECT TO A RIGHT OF REPURCHASE OPTION HELD BY THE ISSUER AND/OR ITS ASSIGNEE(S) AS SET FORTH IN A CERTAIN RESTRICTED STOCK PURCHASE AGREEMENT BETWEEN THE ISSUER AND THE ORIGINAL HOLDER OF THESE SHARES, A COPY OF WHICH MAY BE OBTAINED AT THE PRINCIPAL OFFICE OF THE ISSUER, SUCH RIGHT TO REPURCHASE IS BINDING ON THE TRANSFEREES OF THESE SHARES.”
		

			
	
			
				 6.
			Rights as a Shareholder.  Except as otherwise provided in this Agreement, for so long as the Participant is the registered owner of the Restricted Shares, the Participant shall have all rights as a shareholder with respect to the Restricted Shares, whether vested or unvested, including, without limitation, rights to vote the Restricted Shares and act in respect of the Restricted Shares at any meeting of shareholders; provided that the payment of dividends on unvested Restricted Shares shall be deferred until, and shall only be paid at, such time as the shares vest.

			
	
			
				 7.
			Provisions of the Plan.  This Agreement is subject to the provisions of the Plan, a copy of which is furnished to the Participant with this Agreement.

			
	
			
				 8.
			Tax Matters.

			
	
			
				 (a)
			Acknowledgments; Section 83(b) Election.  The Participant acknowledges that he or she is responsible for obtaining the advice of the Participant’s own tax advisors with respect to the acquisition of the Restricted Shares and the Participant is relying solely on such advisors and not on any statements or representations of the Company or any of its agents with respect to the tax consequences relating to the Restricted Shares.  The Participant understands that the Participant (and not the Company) shall be responsible for the Participant’s tax liability that may arise in connection with the acquisition, vesting and/or disposition of the Restricted Shares.

		
			THE PARTICIPANT ACKNOWLEDGES HE OR SHE SHALL NOT MAKE AN ELECTION UNDER SECTION 83(b) OF THE INTERNAL REVENUE CODE OF 1986, AS AMENDED.
		

			
	
			
				 (b)
			Withholding.  The Participant acknowledges and agrees that the Company has the right to deduct from payments of any kind otherwise due to the Participant any federal, state, local or other taxes of any kind required by law to be withheld with respect to the issuance or vesting of the Restricted Shares. The Company shall not remove the restrictive legend described in Section 5 hereof from any shares of Common Stock until it is satisfied that all its required withholdings have been made.  The Participant acknowledges and agrees that the Company has the right to deduct from 

		 

		

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	payments of any kind otherwise due to the Participant any federal, state, local or other taxes of any kind required by law to be withheld with respect to the issuance or vesting of the Restricted Shares.

			
	
			
				 9.
			Miscellaneous.

		
			(a)Authority of Board.  In making any decisions or taking any actions with respect to the matters covered by this Agreement, the Company’s Board of Directors (the “Board”) or any one or more of the committees or subcommittees of the Board to which the Board delegates its powers in accordance with the terms of the Plan shall have all of the authority and discretion, and shall be subject to all of the protections, provided for in the Plan.  All decisions and actions by the Board or any one or more of its committees or subcommittees to which its powers have been delegated with respect to this Agreement shall be made in its discretion and shall be final and binding on the Participant.
		

		
			(b)No Right to Continued Service.  The Participant acknowledges and agrees that, notwithstanding the fact that the vesting of the Restricted Shares is contingent upon his or her continued service to the Company, this Agreement does not constitute an express or implied promise of a  continued service relationship or confer upon the Participant any rights with respect to a  continued service relationship by the Company.
		

		
			(c)Governing Law.  This Agreement shall be construed, interpreted and enforced in accordance with the internal laws of the State of Delaware, without regard to any applicable conflicts of law provisions.
		

		
			(d)Participant’s Acknowledgments.  The Participant acknowledges that (i) he or she has read this Agreement, has received and read the Plan, and understands the terms and conditions of this Agreement and the Plan, and (ii) that he or she agrees that in accepting this award, he or she will be bound by any clawback policy that the Company has in effect or may adopt in the future.
		

		
			 
		

		 

		

			4edit_Ex10_2

		

			 

		

		
			Exhibit 10.2
		

			
					
						 

					
					
						Confidential Materials omitted and filed separately with the

					
					
						 

				
	
					
						 

					
					
						Securities and Exchange Commission. Double asterisks denote omissions.

					
					
						 

				

		
			FIRST AMENDMENT TO LICENSE AGREEMENT
		

		
			This First Amendment, dated September 1, 2017 (the “First Amendment”), is by and between Editas Medicine, Inc., a Delaware corporation (“Licensee”) and Duke University, a nonprofit educational and research institution organized under the laws of North Carolina ("DUKE").
		

		
			WHEREAS, Licensee and DUKE entered into a license agreement dated October 10, 2014 (the "License Agreement"); and
		

		
			WHEREAS, DUKE and Licensee desire to modify certain provisions of the License Agreement as provided herein. 
		

		
			NOW THEREFORE, for and in consideration of the promises and mutual covenants herein contained DUKE and Licensee hereby agree as follows:
		

		
			1.           Section 1.6 of the License Agreement shall be deleted in its entirety and the following inserted in lieu thereof:
		

		
			1.6         “Field of Use” means the prevention and/or treatment of human disease.  For clarity, Field of Use specifically excludes (i) identifying or producing small or large molecules discovered using the technology covered by the Patents, including for the prevention and/or treatment of human disease, unless such small or large molecules are used for gene therapy, or used for the editing, modifying or targeting of DNA or RNA, in each case, in association with the use of CRISPR technology (other than the use of CRISPR technology for the making of such small or large molecules) (“Small or Large Molecule Treatment Activities”), and (ii) internal research in any field, including the Life Sciences Research Reagent Market. Found in Articles 2.1, 2.3, 2.7, 4.1 and 5.1.
		

		
			2.           Section 2.2 of the License Agreement shall be deleted in its entirety and the following inserted in lieu thereof:
		

		
			2.2         Non-Exclusive License Grant Under the Patents. Subject to the terms and conditions of this Agreement, DUKE grants to Licensee and Licensee accepts from DUKE (i) a non-exclusive, sublicensable license under the Patents for Small or Large Molecule Treatment Activities and internal research in the Field of Use, including target discovery and (ii) a non-exclusive, non-sublicensable license under the Patents for Small or Large Molecule Treatment Activities and internal research in any field outside the Field of Use, including target discovery and the Life Sciences Research Reagent Market.  The license granted in this Article 2.2 (ii) shall
		

		
			
		

		
			

		 

 

		

			 

		

		

		
			expire on the fifth anniversary of the Effective Date, provided that Licensee may extend such expiration date by three (3) years upon written notice to DUKE at least [**] days in advance of the original expiration date and payment to DUKE of $[**] and provided further that Licensee may terminate the license granted in this Article 2.2, without affecting any other provision of this Agreement, at any time upon [**] days advance written notice to DUKE.
		

		
			3.           Sections 8.2, 8.3 and 8.4 of the License Agreement shall be deleted in their entirety and the following inserted in lieu thereof:
		

		
			8.2         Enforcement of Patents. If Licensee becomes aware of any alleged infringement of the Patents in the Field of Use by a Third Party, Licensee shall, during the Term of this Agreement, have the right, but not the obligation, upon advance written notice to DUKE, to either:
		

		
			(a)    resolve such infringement by sublicensing the Patents in the Field of Use to the alleged infringer or by other means if not expressly prohibited under this Agreement, or
		

		
			(b)    prosecute or defend at its own expense an action to resolve such infringement. In the event Licensee prosecutes such infringement, Licensee may, for such purposes, request to use the name of DUKE as party plaintiff.  If DUKE is required by law to join such action as a party plaintiff, DUKE may, at its sole discretion, agree to become a party plaintiff, and all costs associated therewith shall be borne by Licensee. If DUKE becomes a Party plaintiff, DUKE shall have the right to approve the counsel with primary responsibility for the enforcement. If joint representation is deemed to be inappropriate because of actual or potential differences in the interests of Licensee and DUKE, Licensee shall pay the out-of-pocket costs and expenses of separate counsel to DUKE.
		

		
			In the event that Licensee does not take any action to abate infringement of the Patents in the Field of Use against a party after Licensee becomes aware of such infringing activity of the party within [**] months from being aware of such infringing activity, DUKE shall have the right, but not the obligation, to institute an action against the infringing party with respect to such infringement; provided, however, that DUKE shall not initiate a suit or other enforcement action concerning infringement of the Patents in the Field of Use without first consulting Licensee and giving due consideration to Licensee’s reasons for not initiating an action or otherwise prosecuting a claim.  Notwithstanding anything to the contrary herein, DUKE shall have the exclusive right to pursue actual or alleged infringement of the Patents outside the  Field of Use, at its own cost, without limitation and without obligation to Licensee (except as set forth in Articles 8.1 and 8.4), including the right to grant, without obligation to Licensee, such right to pursue actual or alleged infringement of the Patents outside the Field of Use, without obligation to Licensee, to Third Parties.  DUKE shall consult with Licensee prior to initiating any suit or other enforcement action against an alleged infringer outside of the Field of Use and shall give due consideration to the Company’s reasons for not initiating an action or otherwise prosecuting a claim of infringement, which reasons will not be unreasonably disregarded, prior to initating such suit or enforcement action.
		

		
			 
		

		
			
		

		
			

		 

 

		

			 

		

		

		
			8.3         Recovery of Damages and Costs.
		

		
			(a)    In the event DUKE undertakes the enforcement and/or defense of the Patents by litigation, including any declaratory judgment action, DUKE may request the use of the name of Licensee as a party plaintiff in any such suit without expense to Licensee; provided however that Licensee may, in its sole discretion, refuse such request so long as Licensee is not obligated by a court of law for joinder purposes to join as a party plaintiff. The total cost of any such infringement action commenced or defended solely by DUKE shall be borne by DUKE. Any recovery of damages by DUKE for any infringement of the Patents in the Field of Use shall be applied first in satisfaction of any unreimbursed expenses and attorneys’ fees of DUKE relating to the suit, and second toward reimbursement of Licensee’s reasonable expenses, including reasonable attorneys’ fees, relating to the suit. Any balance remaining from such recovery shall, to the extent solely concerning infringement of the Patents in the Field of Use, be distributed with DUKE receiving [**] percent ([**]%).  Notwithstanding anything to the contrary, however, Licensee shall not be entitled to retain or be paid any amounts paid by or received from Third Parties with respect to any infringement of the Patents outside the Field of Use.
		

		
			(b)    In the event that Licensee undertakes the enforcement and/or defense of the Patents in the Field of Use by litigation, including any declaratory judgment action pursuant to Article 8.2(b), the total cost of any such action commenced or defended solely by Licensee shall be borne by Licensee. Any recovery of damages by Licensee as a result of such action shall be applied first in satisfaction of any unreimbursed expenses and attorneys’ fees of Licensee relating to the action, and second in satisfaction of unreimbursed legal expenses and attorneys’ fees of DUKE, if any, relating to the action subject to Article 8.4. If applicable, Licensee shall receive, as its portion of any such recovery of damages, an amount equal to its lost profits or a reasonable royalty on Sales of the infringer (whichever measure of damages the court shall have applied), less a reasonable approximation of the royalties that Licensee would have owed to DUKE on Net Sales that were lost to the infringer, which amount shall be promptly paid by Licensee to DUKE. Any balance remaining from such recovery that is related to the Patents within the Field of Use shall be distributed between Licensee and DUKE with Licensee receiving [**] percent ([**]%) and DUKE receiving [**] percent ([**]%). 
		

		
			8.4         Cooperation of the Parties.
		

		
			(a)    If a Party undertakes an infringement suit in the Field of Use with respect to the Patents against a Third Party as permitted under this Agreement (the “controlling Party”), upon that Party’s reasonable request, the other Party (the “cooperating Party”) shall provide the controlling Party with such assistance and information as may be required by the suit. Such information and assistance includes having the cooperating Party’s employees testify when necessary to the suit and making available, for example, relevant records, papers, information,
		

		
			
		

		
			

		 

 

		

			 

		

		

		
			samples, and specimens. At all times, the cooperating Party shall have the right to select and to utilize independent counsel to advise the cooperating Party regarding the action.  The controlling Party shall reimburse the cooperating Party for all reasonable fees and costs incurred by the cooperating Party arising from its cooperation as requested by the controlling Party, including fees and costs charged by independent counsel. Before any such fees or costs are incurred, the controlling Party shall be entitled to notice of the rates at which such fees and costs will be incurred, and the cooperating Party will work in good faith with the controlling Party to minimize such fees and costs. The controlling Party shall keep the cooperating Party informed of progress of such proceedings and shall make its independent counsel available to cooperating Party.  The cooperating Party shall have the right to select and to utilize independent counsel to advise the cooperating Party regarding the action, but at the cooperating Party’s own expense, said expense to be eligible for reimbursement in connection with a recovery of damages in accordance with Article 8.3 only if representation of the cooperating Party by counsel to the controlling Party bringing suit would be inappropriate because of conflicts of interest.
		

		
			(b)    Licensee agrees that DUKE shall be entitled to disclose, under reasonable conditions of confidentiality, any notice or information provided to DUKE by Licensee concerning any alleged or actual infringement of the Patents by a Third Party, or litigation or settlement activities with respect thereto, to any Third Party licensees of DUKE under the Patents. If and as requested by Licensee, DUKE shall use reasonable efforts to facilitate communications between Licensee and any Third Party licensees of DUKE with respect to the Patents with respect to matters concerning the infringement of the Patents inside or outside the Field of Use, or litigation or settlement activities with respect thereto, including as may be necessary to coordinate the actions of Licensee, such Third Party, and/or DUKE in order to effect the purposes of this Article 8 or any corresponding provision of any agreement between DUKE and any Third Party concerning rights to Patents outside the Field of Use.  Licensee, at DUKE’s request, shall communicate with such Third Party licensees of DUKE regarding questions or issues that Third Party licensee may identify with respect to matters concerning the infringement of the Patents inside or outside the Field of Use (or litigation or settlement activities with respect thereto).   Notwithstanding anything to the contrary, however, any disclosure required or permitted under this Article 8.4(b) shall be subject to (i) no Party violating, or being required to waive, attorney-client privilege with respect to any information and (ii) the confidentiality protections of Article 11 (or a separate, mutually agreeable nondisclosure or confidentiality agreement between the Parties).  
		

		
			4.           Existing Appendix A shall be deleted and replaced with Appendix A attached to this First Amendment.
		

		
			5.           Existing Appendix C shall be deleted and replaced with Appendix C attached to this First Amendment.
		

		
			6.           Except as specifically modified and amended herein, all other terms and conditions of the License Agreement remain unchanged and in effect and are hereby ratified and adopted as though fully set forth herein.
		

		
			
		

		
			

		 

 

		

			 

		

		

		
			7.           This First Amendment may be executed in one or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. 
		

		
			IN WITNESS WHEREOF, the parties have entered into this Amendment to the Amended Agreement as of the date and year first above-written.
		

			
					
						 

					
						 

					
					
						 

					
					
						 

					
					
						 

					
					
						 

				
	
					
						EDITAS MEDICINE

					
					
						    

					
					
						DUKE UNIVERSITY

				
	
					
						 

					
					
						 

					
					
						 

				
	
					
						By:

					
					
						/s/ Andrew Hack

					
					
						 

					
					
						By

					
					
						/s/ Robin Rasor

				
	
					
						 

					
					
						Andrew Hack

					
					
						 

					
					
						 

					
					
						 

				
	
					
						 

					
					
						 

					
					
						 

					
					
						 

					
					
						 

				
	
					
						Title:

					
					
						Chief Financial Officer

					
					
						 

					
					
						Title

					
					
						Executive Director, Office of Licensing 

				
	
					
						 

					
					
						 

					
					
						 

					
					
						 

					
					
						& Ventures, Duke University and DUMC

				

		
			 
		

		
			

		 

 

		

			 

		

APPENDIX A—PATENTS
		

		
			Intellectual property contained in Duke’s Office of Licensing & Ventures files #[**] and to patents and patent applications derived from (Patents), all to the extent to which Editas Medicine would need a license to practice in the Field of Use.  
		

			
					
						 

					
					
						 

					
					
						 

					
					
						 

				
	
					
						IDF No.

					
					
						App No.

					
					
						Patent No.

					
					
						App. Title

				
	
					
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APPENDIX C – DEVELOPMENT SCHEDULE
		

		
			For a Licensed Product for the treatment of Duchenne Muscular Dystrophy:
		

		
			[**]
		

		
			For a Licensed Product other than for the treatment of Duchenne Muscular Dystrophy (e.g., a non DMD product):
		

		
			[**]

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