Document:

<PAGE>

                                                                    Exhibit 10.1

                           ORCHID BIOCOMPUTER, INC.
                           1995 STOCK INCENTIVE PLAN
                           -------------------------

                                   SECTION 1
                                    Purpose
                                    -------

          This Orchid Biocomputer, Inc. 1995 Stock Incentive Plan (the "Plan")
is intended to provide a means whereby Orchid Biocomputer, Inc. (the "Company")
may, through (i) the grant of incentive stock options and nonqualified stock
options (collectively, the "Options") to Employees (as defined in Section 3),
(ii) the grant of nonqualified stock options to Non-Employee Directors and
Consultants (as defined in Section 3), and (iii) the grant of stock subject to
restrictions ("Restricted Stock Awards") to Employees, Non-Employee Directors
and Consultants, attract and retain such individuals and motivate them to
exercise their best efforts on behalf of the Company and of any Related
Corporation (as defined below).

          For purposes of the Plan, a Related Corporation shall mean either a
subsidiary corporation of the Company, as defined in section 424(f) of the
Internal Revenue Code of 1986, as amended (the "Code"), or the parent
corporation of the Company, as defined in section 424(e) of the Code.  Further,
as used in the Plan, (i) the term incentive stock option ("ISO") shall mean an
Option which, at the time such option is granted under the Plan, qualifies as an
ISO within the meaning of section 422 of the Code and is designated as an ISO in
the Option Agreement (as defined in Section 6(c)); and (ii) the term
nonqualified stock option ("NQSO") shall mean an option which, at the time such
option is granted, does not qualify as an ISO, and is designated as an NQSO in
the Option Agreement.

                                   SECTION 2
                                Administration
                                --------------

          (a)  The Plan shall be administered (i) by the Company's Compensation
Committee, which shall consist of not less than three directors of the Company
who shall be appointed by, and shall serve at the pleasure of, the Company's
Board of Directors (the "Board"), or (ii) in the event a Compensation Committee
has not been established, by the entire Board, (the "Committee").  Each member
of the Committee, while serving as such, shall be deemed to be acting in his
capacity as a director of the Company.

          (b)  On and after the date the Company first registers equity
securities under section 12 of the Securities Exchange Act of 1934 (the
"Exchange Act") (the "Registration Date"), the Board shall change the membership
of the Committee, to the extent necessary, and the Committee shall thereafter be
composed, such that the Plan complies with the provisions of Rule 16b-3 under
the Exchange Act or any successor provisions thereto.

          (c)  At such time as the Committee reasonably determines that
remuneration payable pursuant to any Award under the Plan qualifies as
applicable employee remuneration (as defined in section 162(m) of the Code and
regulations thereunder), the Board shall change the
<PAGE>

membership of the Committee, to the extent necessary, and the Committee shall
thereafter be composed, such that each member of the Committee shall be an
outside director (as defined in regulations or rules under section 162 (m) of
the Code).

          (d)  The Committee shall have full authority, subject to the terms of
the Plan, to select the Employees, Non-Employee Directors and Consultants to be
granted Restricted Stock Awards and Options ("Awards") under the Plan, to grant
Awards on behalf of the Company, and to set the date of grant and the other
terms of such Awards; provided, however, that a grant of an Award to a member of
the Committee made pursuant to the terms of the Plan shall be made by (and the
terms of such Award shall be set by) a majority of the members of the Board
excluding such Committee member; and provided further, however, that action by
the Committee when not properly composed as set forth in Section 2(a), (b) or
(c) above shall be null, void and of no effect.

          (e)  The Committee may correct any defect, supply any omission and
reconcile any inconsistency in the Plan and in any Award granted hereunder to
the extent it shall deem desirable.  The Committee also shall have the authority
to establish such rules and regulations, not inconsistent with the provisions of
the Plan, for the proper administration of the Plan, and to amend, modify, or
rescind any such rules and regulations, and to make such determinations, and
interpretations under, or in connection with, the Plan, as it deems necessary or
advisable.  All such rules, regulations, determinations, and interpretations
shall be binding and conclusive upon the Company, its stockholders and all
employees, and upon their respective legal representatives, beneficiaries,
successors, and assigns and upon all other persons claiming under or through any
of them.

          (f)  No member of the Board or the Committee shall be liable for any
action or determination made in good faith with respect to the Plan or any Award
granted under it.

                                   SECTION 3
                                  Eligibility
                                  -----------

          The following individuals shall be eligible to receive Awards under
the Plan:

          (a)  Employees.  Officers and other employees (including any directors
               ---------
who are also employees) of the Company and Related Corporations ("Employees")
shall be eligible to receive ISOs, NQSOs and Restricted Stock Awards under the
Plan.

          (b)  Non-Employee Directors and Consultants.  Directors of the Company
               --------------------------------------
who are not officers or employees ("Non-Employee Directors") and independent
consultants or advisors hired by the Company to render bona fide services to the
                                                       ---------
Company or a Related Corporation ("Consultants") shall be eligible to receive
NQSOs and Restricted Stock Awards, but not ISOs, under the Plan.

                                       2
<PAGE>

          More than one Award may be granted to an Employee, Non-Employee
Director or Consultant ("Eligible Individual") under the Plan.  Eligible
Individuals who have been granted an Award under the Plan shall be referred to
as "Grantees."

                                   SECTION 4
                                     Stock
                                     -----

          The number of common shares of the Company, par value $0.00l per share
("Common Shares"), that may be subject to Awards under the Plan shall be
3,500,000 Shares, subject to adjustment as hereinafter provided. Shares issuable
under the Plan may be authorized but unissued shares or reacquired share, and
the Company may purchase shares required for this purpose, from time to time, if
it deems such purchase to be advisable.

          Any Common Shares subject to an Option which expires or otherwise
terminates for any reason whatever (including, without limitation, the Grantee's
surrender thereof) without having been exercised, and any shares of Restricted
Stock which are forfeited, shall continue to be available for the granting of
Awards under the Plan; provided, however, that (i) if an Option is cancelled,
the Common Shares covered by the cancelled Option shall be counted against the
maximum number of shares for which Options may be granted to an Employee, and
(ii) if the Option price is reduced after the date of grant, the transaction
shall be treated as a cancellation of an Option and the grant of a new Option
for purposes of counting the maximum number of shares for which Options may be
granted to an Employee.

                                   SECTION 5
                                 Annual Limit
                                 ------------

          (a)  ISOs. The aggregate Fair Market Value (as defined in Section 6(b)
               ----
(2)) as of the date the ISO is granted of the Common Shares with respect to
which ISOs are exercisable for the first time by an Employee during any calendar
year (under this Plan and any other ISO plan of the Company or a Related
Corporation) shall not exceed $100,000.  To the extent the aggregate Fair Market
Value of the Common Shares for which ISOs are exercisable for the first time by
any Employee during any calendar year exceeds $100,000, such excess ISOs shall
be treated as NQSOs.

          (b)  NQSOs and Restricted Stock Awards.  The annual limits set forth
               ---------------------------------
above for ISOs shall not apply to NQSOs and Restricted Stock Awards.

                                   SECTION 6
                                    Options
                                    -------

          (a)  Granting of Options.  From time to time until the expiration or
               -------------------
earlier suspension or discontinuance of the Plan, the Committee may, on behalf
of the Company, grant to Eligible Individuals under the Plan such Options as it
determines are warranted; provided, however, that grants of ISOs and NQSOs shall
be separate and not in tandem; and further provided that Non-Employee Directors
and Consultants shall not be eligible to receive ISOs.  In making any
determination as to whether an Eligible Individual shall be granted an Option
and as

                                       3
<PAGE>

to the number of shares to be covered by such Option, the Committee shall take
into account the duties of the Eligible Individual, his present and potential
contributions to the success of the Company or a Related Corporation, the tax
implications to the Company and the Eligible Individual of any Options granted,
and such other factors as the Committee shall deem relevant in accomplishing the
purposes of the Plan. Moreover, the Committee may provide in the Option
Agreement that said Option may be exercised only if certain conditions, as
determined by the Committee, are fulfilled.

          (b)  Terms and Conditions of Options. The Options granted to Employees
               -------------------------------
pursuant to the Plan shall expressly specify whether they are ISOs or NQSOs.
The Options granted to Non-Employee Directors and Consultants pursuant to the
Plan shall expressly specify that they are NQSOs.  In addition, the Options
granted pursuant to the Plan shall include expressly or by reference the
following terms and conditions, as well as such other provisions not
inconsistent with the provisions of this Plan and, for ISOs granted under this
Plan, the provisions of section 422(b) of the Code, as the Committee shall deem
desirable:

               (1)  Number of Shares.  The Option shall state the number of
                    ----------------
     shares to which the Option pertains.

               (2)  Price.  The Option shall state the Option exercise price
                    -----
     which shall be determined and fixed by the Committee in its discretion at
     the time of grant but, in the case of an ISO, shall not be less than the
     higher of 100 percent (110 percent in the case of a grant to a more-than10-
     percent stockholder, as discussed in Section 6(b) (8)) of the Fair Market
     Value of the optioned Common Shares, or the par value thereof, on the date
     the ISO is granted and, in the case of an NQSO, shall not be less than the
     higher of 100 percent of the Fair Market Value of the optioned Common
     Shares, or the par value thereof, on the date the NQSO is granted.

          The Fair Market Value of the optioned Common Shares on a given date
means (i) if the Common Shares are listed on a national securities exchange, the
mean between the highest and lowest sale prices reported as having occurred on
the primary exchange with which the Common Shares are listed and traded on the
date prior to such date, or if there is no such sale on that date, then on the
last preceding date on which such sale was reported; (ii) if the Common Shares
are not listed on any national securities exchange but are quoted on the
National Market System of the National Association of Securities Dealers
Automated Quotation System on a last sale basis, the average between the high
bid price and low ask price reported on the date prior to such date, or, if
there is no such sale on that date, then on the last preceding date on which a
sale was reported; or (iii) if the Common Shares are not listed on a national
securities exchange nor quoted on the National Market System of the National
Association of Securities Dealers Automated Quotation System on a last sale
basis, the amount determined by the Committee to be the fair market value based
upon a good faith attempt to value the Common Shares accurately and computed in
accordance with the applicable regulations of the Internal Revenue Service.

                                       4
<PAGE>

               (3)  Term.
                    ----

                    (A)  ISOs.  Subject to earlier termination as provided in
                         ----
          Sections 6(b)(5), (6) and (7) and in Section 8 hereof, the term of
          each ISO shall be not more than 10 years (five years in the case of an
          ISO granted to a more-than-10-percent stockholder, as discussed in
          Section (6) (b) (8)) from the date of grant.

                    (B)  NQSOs.  Subject to earlier termination as provided in
                         -----
          Sections 6(b)(5), (6) and (7) and in Section 8 hereof, the term of
          each NQSO shall be not more than 10 years from the date of grant.

               (4)  Exercise.  Options shall be exercisable in such installments
                    --------
     and on such dates, not less than 6 months after the date of grant as the
     Committee may specify; provided that (i) in the case of new Options granted
     to an Eligible Individual in replacement for options (whether granted under
     the Plan or otherwise) held by the Eligible Individual, the new Options may
     be made exercisable at the earliest date the replaced options were
     exercisable, but not earlier than 3 months after the date of grant of the
     new Options, and (ii) the Committee may accelerate the exercise date of any
     outstanding Options (including, without limitation, the 3 and 6-month
     exercise dates referred to above), in its discretion, if it deems such
     acceleration to be desirable.

          Any Common Shares, the right to the purchase of which has accrued, may
be purchased at any time up to the expiration or termination of the Option.
Exercisable Options may be exercised, in whole or in part, from time to time by
giving written notice of exercise to the Company at its principal office,
specifying the number of Common Shares to be purchased and accompanied by
payment in full of the aggregate Option exercise price for such Shares.  Only
full Shares shall be issued under the Plan, and any fractional Share which might
otherwise be issuable upon exercise of an Option granted hereunder shall be
forfeited.

     The Option price shall be payable --

               (A)  in cash or its equivalent;

               (B)  in the discretion of the Committee, in Common Shares
     previously acquired by the Grantee; provided that (i) if such Common Shares
     were acquired through the exercise of an ISO and are used to pay the Option
     price for ISOs, such shares have been held by the Employee for a period of
     not less than the holding period described in section 422(a) (1) of the
     Code on the date of exercise, or if (ii) such Common Shares were acquired
     through the exercise of an NQSO or the vesting of a Restricted Stock Award
     and are used to pay the Option price of an ISO, or if such Common Shares
     were acquired through the exercise of an ISO, an NQSO or the vesting of a
     Restricted Stock Award and are used to pay the Option price of an NQSO,
     such shares have been held by the Grantee for a period of more than one
     year on the date of exercise;

                                       5
<PAGE>

               (C)  in the discretion of the Committee, in Common Shares newly
     acquired by the Grantee upon exercise of such Option (which shall
     constitute a disqualifying disposition in the case of an Option which is an
     ISO);

               (D)  in the discretion of the Committee, in any combination of
     subparagraphs (A), (B) and (C) above; or

               (E)  in the discretion of the Committee, by delivering a properly
     executed notice of exercise of the Option to the Company and a broker, with
     irrevocable instructions to the broker promptly to deliver to the Company
     the amount of sale or loan proceeds necessary to pay the exercise price of
     the Option.

          In the event the Option price is paid, in whole or in part, with
Common Shares, the portion of the Option price so paid shall be equal to the
Fair Market Value on the date of exercise of the Option of the Common Shares so
surrendered in payment of the Option price.

               (5)  Termination of Employment, Consulting Services or Board
                    -------------------------------------------------------
     Membership.  If a Grantee's employment relationship, consulting
     ----------
     relationship or directorship with the Company (and Related Corporations, as
     the case may be) is terminated by either party prior to the expiration date
     fixed for his Option for any reason other than death, disability or Cause,
     such Option may be exercised, to the extent of the number of Common Shares
     with respect to which the Grantee could have exercised it on the date of
     such termination, or to any greater extent permitted by the Committee, by
     the Grantee at any time prior to the earlier of (i) the expiration date
     specified in such Option, or (ii) that date which is three months after the
     Grantee's termination of employment, consulting relationship or
     directorship, as the case may be.

               (6)  Exercise upon Disability of Grantee.  If a Grantee's
                    -----------------------------------
     employment relationship, consulting relationship or directorship with the
     Company (and Related Corporations, as the case may be) is terminated as a
     consequence of Grantee's becoming disabled (within the meaning of section
     22(e) (3) of the Code) during his employment by the Company (and Related
     Corporations), his provision of consulting services to the Company (and
     Related Corporations), his membership on the Board or during the three
     month period after termination of such relationship with the Company as
     provided for in Section 6(b) (5) above, and prior to the expiration date
     fixed for his Option, such Option may be exercised, to the extent of the
     number of shares with respect to which the Grantee could have exercised it
     on the date of such termination, or to any greater extent permitted by the
     Committee, by the Grantee at any time prior to the earlier of (i) the
     expiration date specified in such Option, or (ii) that date which is six
     months after the Grantee's termination of employment, engagement or
     membership, as the case may be.  In the event of the Grantee's legal
     disability, such Option may be so exercised by the Grantee's legal
     representative.

               (7)  Exercise upon Death of Grantee.  If a Grantee's employment
                    ------------------------------
     relationship, consulting relationship or directorship with the Company (and
     Related Corporations, as the case may be) is terminated as a consequence of
     Grantee's death

                                       6
<PAGE>

     during his employment by the Company (and Related Corporations), his
     provision of consulting services to the Company (and Related Corporations),
     his membership on the Board or during the three or six month period after
     termination of such relationship with the Company as provided for in
     Section 6(b) (5) or (6) above, and prior to the expiration date fixed for
     his Option, such Option may be exercised, to the extent of the number of
     Common Shares with respect to which the Grantee could have exercised it on
     the date of his death, or to any greater extent permitted by the Committee,
     by the Grantee's estate, personal representative or beneficiary who
     acquired the right to exercise such Option by bequest or inheritance or by
     reason of the death of the Grantee. Such post-death exercise may occur at
     any time prior to the earlier of (i) the expiration date specified in such
     Option or (ii) that date which is one year after the Grantee's date of
     death.

               (8)  Ten Percent Stockholder.  If the Employee owns more than 10
                    -----------------------
     percent of the total combined voting power of all shares of stock of the
     Company or of a Related Corporation at the time an ISO is granted to him,
     the Option price for the ISO shall be not less than 110 percent of the Fair
     Market Value of the optioned Common Shares on the date the ISO is granted,
     and such ISO, by its terms, shall not be exercisable after the expiration
     of five years from the date the ISO is granted.  The conditions set forth
     in this paragraph shall not apply to NQSOs.

               (9)  Expiration upon Termination for Cause.  If a Grantee's
                    -------------------------------------
     employment relationship, consulting relationship or directorship with the
     Company (or any Related Corporation, as the case may be) is terminated by
     the Company (or any Related Corporation, as the case may be) for Cause, all
     of his unexercised Options shall immediately expire and any and all rights
     thereunder shall be forfeited. The Company (or any Related Corporation, as
     the case may be) shall have Cause to terminate a Grantee's employment or
     consulting relationship with the Company (or any Related Corporation, as
     the case may be) if the Company (or any Related Corporation, as the case
     may be) has Cause pursuant to any existing employment, consulting or any
     other agreement between the Grantee and the Company (or any Related
     Corporation, as the case may be), or, in the absence of such an employment,
     consulting or any other agreement, upon (i) the determination by the
     Committee that Grantee has ceased to perform his duties to the Company (or
     any Related Corporation, as the case may be) (other than as a result of his
     incapacity due to physical or mental injury), which failure amounts to an
     intentional and extended neglect of his duties to such party, (ii) the
     Committee's determination that the Grantee has engaged or is about to
     engage in conduct materially injurious to the Company (or any Related
     Corporation, as the case may be) or (iii) the Grantee having been convicted
     of a felony.

                                       7
<PAGE>

          (c)  Option Agreements.  Options granted under the Plan shall be
               -----------------
evidenced by written documents ("Option Agreements") in such form as the
Committee shall from time to time approve, and containing such provisions not
inconsistent with the provisions of the Plan (and, for ISOs, not inconsistent
with section 422 of the Code), as the Committee shall deem advisable. The Option
Agreements shall specify whether the Option is an ISO or NQSO. Each Grantee
shall enter into, and be bound by, such an Option Agreement, as soon as
practicable after the grant of an Option.

                                   SECTION 7
                            Restricted Stock Awards
                            -----------------------

          From time to time until the expiration or earlier termination of the
Plan, the Committee may, on behalf of the Company, make such Restricted Stock
Awards under the Plan to Eligible Individuals as it determines are warranted.
Restricted Stock Awards shall be subject to the following terms and conditions,
as well as such other terms and conditions as the Committee may prescribe:

          (a)  Vesting Period; Conditions.  At the time of granting a Restricted
               --------------------------
Stock Award, the Committee may establish one or more vesting periods ("Vesting
Periods") with respect to the Common Shares covered by the Award; provided that
no more than 20% of the Common Shares covered by an Award or Awards to a Grantee
may have an initial stated Vesting Period of less than six months. The length of
any such Vesting Period(s) applicable to a Restricted Stock Award shall be
within the discretion of the Committee. At the time of grant, the Committee also
may establish such additional conditions to the payment of a Restricted Stock
Award ("Conditions") as it may deem advisable in its sole discretion, such as
the achievement of corporate or individual goals. Subject to the provisions of
this Section 7 and any other Conditions prescribed by the Committee, shares
subject to a Restricted Stock Award shall vest in the Grantee upon the
expiration of the Vesting Period with respect to such shares. Notwithstanding
any provision herein to the contrary, the Committee may accelerate the vesting
date of any uninvested shares subject to a Restricted Stock Award in its
discretion, if it deems such acceleration of vesting to be desirable.

          (b)  Issuance and Delivery of Certificates.  Upon the granting of a
               -------------------------------------
Restricted Stock Award, (i) the Company may, if so determined by the Committee
at the time of the grant, issue certificates in the name of the Grantee
representing the Common Shares subject to the Restricted Stock Award which are
subject to Vesting Periods and/or Conditions, and (ii) the Company shall issue
certificates in the name of the Grantee representing the Common Shares subject
to the Award which are not subject to Vesting Periods or Conditions. Any such
shares subject to Vesting Periods and/or Conditions shall bear a legend
indicating that they are subject to the terms of the Plan and the Restricted
Stock Award Agreement (as defined in Section 7(f)) and that they may not be
sold, exchanged, transferred, pledged, hypothecated or otherwise disposed of
except in accordance with the terms of the Plan and the Restricted Stock Award
Agreement. Upon issuance of such legended certificates, the Grantee shall
immediately execute a stock power or other instrument of transfer, appropriately
endorsed in blank, to be held by the Company pursuant to the terms of the Plan
and the Restricted Stock Award Agreement. Only full shares

                                       8
<PAGE>

shall be issued, and any fractional shares which might otherwise be issuable
pursuant to a Restricted Stock Award shall be forfeited.

          (c)  Rights as a Shareholder.  If the Company issues certificates
               -----------------------
representing the shares subject to a Restricted Stock Award prior to the
expiration of the Vesting Period for the shares subject to such Award or prior
to the satisfaction of the Conditions, if any, pertaining to such Award, the
Grantee shall be entitled to receive dividends paid on such shares, shall have
the right to vote such shares, and shall have all other shareholder's rights
with respect to such shares, except that (i) the Grantee will not be entitled to
delivery of the stock certificate, (ii) the Company will retain custody of the
Common Shares, and (iii) the shares subject to the Restricted Stock Award will
revert to the Company to the extent all Vesting Periods and Conditions
applicable to such Award are not satisfied.

          (d)  Termination of Employment, Consulting Services or Board
               -------------------------------------------------------
Membership.  At the time of granting a Restricted Stock Award, the Committee
----------
shall specify in the Restricted Stock Award Agreement, the manner of determining
the number, if any, of unvested shares subject to the Award which shall become
vested in the Grantee, or in his beneficiary or estate, if employment by the
Company and Related Corporations (where the Grantee is an Employee), engagement
by the Company and Related Corporations (where the Grantee is a Consultant), or
Board membership (where the Grantee is a Non-Employee Director) is terminated
prior to the later of the expiration of the Vesting Period or the satisfaction
of all of the Conditions with respect to such shares.  Any Restricted Stock
Award Agreement may provide different vesting provisions upon a Grantee's
termination due to death or disability.  Any remaining shares covered by the
Grantee's Restricted Stock Award not vested pursuant to the terms of the
Restricted Stock Award Agreement shall immediately be forfeited upon termination
of employment, consulting arrangement or Board membership, as applicable, except
that the Committee, if it determines that the circumstances warrant, may direct
that all or a portion of such remaining unvested shares also be vested in the
Grantee, or in his beneficiary or estate, subject to such further terms and
conditions, if any, as the Committee may determine.

          (e)  Payment for Restricted Stock. The Committee may, on behalf of the
               ----------------------------
Company, grant Restricted Stock Awards under which the Grantee shall not be
required to make any payment for the Common Shares upon satisfaction of
applicable Vesting Periods and Conditions or, in the alternative, under which
the Grantee, as a condition to the Restricted Stock Award, shall pay all (or any
lesser amount than all) of the Fair Market Value of the Common Shares,
determined as of the date the Restricted Stock Award is made.  If the latter,
such purchase price shall be paid as provided in the Restricted Stock Award
Agreement.

          (f)  Restricted Stock Award Agreement.  Restricted Stock Awards under
               --------------------------------
the Plan shall be evidenced by written documents ("Restricted Stock Award
Agreements") in such form as the Committee shall, from time to time, approve,
which Restricted Stock Award Agreements shall contain such provisions, not
inconsistent with the provisions of the Plan, as the Committee shall deem
advisable.  Each Grantee shall enter into, and be bound by the terms of, the
Restricted Stock Award Agreement.

                                       9
<PAGE>

                                   SECTION 8
                              Capital Adjustments
                              -------------------

          The number of shares which may be issued under the Plan, the maximum
number of shares with respect to which Options may be granted to any Employee
under the Plan, both as stated in Section 4 hereof, the number of shares
issuable upon exercise of outstanding Options under the Plan (as well as the
Option price per share under such outstanding Options), and the number of Shares
issuable upon the vesting of outstanding Restricted Stock Awards (as well as the
purchase price, if any, for such Shares) shall, subject to the provisions of
section 424(a) of the Code, be adjusted, as may be deemed appropriate by the
Committee, to reflect any stock dividend, stock split, share combination, or
similar change in the capitalization of the Company.

          In the event of a corporate transaction (as that term is described in
section 424(a) of the Code and the Treasury Regulations issued thereunder as,
for example, a merger, consolidation, acquisition of property or stock,
separation, reorganization, or liquidation), each outstanding Award shall be
assumed by the surviving or successor corporation; provided, however, that, in
the event of a proposed corporate transaction, the Committee may terminate all
or a portion of the outstanding Options if it determines that such termination
is in the best interests of the Company. If the Committee decides to terminate
outstanding Options, the Committee shall give each Employee holding an Option to
be terminated not less than seven days' notice prior to any such termination by
reason of such a corporate transaction, and any such Option which is to be so
terminated may be exercised (if and only to the extent that it is then
exercisable) up to, and including the date immediately preceding such
termination. Further, as provided in Section 6(b) (4) and Section 7(a) hereof
the Committee, in its discretion, may accelerate, in whole or in part, the date
on which any or all Options become exercisable, and the vesting date of unvested
shares subject to a Restricted Stock Award, respectively.

          The Committee also may, in its discretion, change the terms of any
outstanding Award to reflect any such corporate transaction, provided that, in
the case of ISOs, such change is excluded from the definition of a
"modification" under section 424(h) of the Code.

                                   SECTION 9
                               Change in Control
                               -----------------

          Unless otherwise determined by the Committee before or after the
granting of an Option or Award, but before the occurrence of a Change in Control
of the Company, all Options may, in the discretion of the Committee, become
fully vested and exercisable, and all Vesting Periods and Conditions for
Restricted Stock Awards may be deemed to have been satisfied, upon a Change in
Control of the Company.  "Change in Control" shall mean the point in time when
(i) any person (as such term is used in section 13 of the Exchange Act and the
rules and regulations thereunder and including any Affiliate or Associate of
such person, as defined in Rule 12b-2 under the Exchange Act, and any person
acting in concert with such person) directly or indirectly acquires or otherwise
becomes entitled to vote more than 50 percent of the voting power entitled to be
cast at elections for directors of the Company, (ii) during any period of two
consecutive

                                      10
<PAGE>

years after the Registration Date, individuals who constitute the Board at the
beginning of such period cease for any reason to constitute at least a majority
thereof, unless the election or nomination for the election by the Company's
shareholders of each new director was approved by a vote of at least three-
quarters of the directors then still in office who were directors at the
beginning of the period or (iii) the Company undergoes a liquidation or
dissolution or a sale of all or substantially all of the assets of the Company.
Neither the initial offering of Common Shares to the public through an effective
registration statement nor any merger, consolidation or corporate reorganization
in which the owners of the combined voting power of the Company's then
outstanding voting securities entitled to vote generally prior to said
combination own 50% or more of the resulting entities' outstanding voting
securities shall, by itself, be considered a Change in Control.

                                  SECTION 10
                    Amendment or Discontinuance of the Plan
                    ---------------------------------------

          At any time and from time to time, the Board may suspend or terminate
the Plan or amend it, and the Committee may amend any outstanding Awards, in any
respect whatsoever, except that the following amendments shall require the
approval of shareholders (given in the manner set forth in Section 12):

               (a)  With respect to ISOs, any amendment which would:

                    (1)  Change the class of employees eligible to participate
               in the Plan;

                    (2)  Except as permitted under Section 8 hereof, increase
               the maximum number of Common Shares with respect to which ISOs
               may be granted under the Plan; or

                    (3)  Extend the duration of the Plan under Section 11 hereof
               with respect to any ISOs granted hereunder.

               (b)  On and after the Registration Date, any amendment which
would:

                    (1)  Materially increase the benefits accruing to directors
               and officers, within the meaning of Rule 16a-l(f) under the
               Exchange Act (hereinafter referred to as "Officers"), under the
               Plan;

                    (2)  Materially increase the number of Common Shares which
               may be issued to directors and Officers under the Plan; or

                    (3)  Materially modify the requirements as to eligibility
               for directors and Officers to participate in the Plan.

                                      11
<PAGE>

               (c)  On and after such date as the Committee reasonably
          determines that remuneration payable pursuant to any Award under the
          Plan qualifies as applicable employee remuneration (as defined in
          section 162 (m) of the Code), any amendment which would require
          shareholder approval pursuant to section 162(m) of the Code and rules
          and regulations issued thereunder.

          Notwithstanding the foregoing, no such suspension, discontinuance or
amendment shall materially impair the rights of any holder of an outstanding
Award without the consent of such holder.

                                  SECTION 11
                              Termination of Plan
                              -------------------

          Unless earlier terminated as provided in the Plan, the Plan and all
authority granted hereunder shall terminate absolutely at 12:00 midnight on
November 28, 2005, which date is within 10 years after the date the Plan was
adopted by the Board, and no Awards hereunder shall be granted thereafter.
Nothing contained in this Section 11, however, shall terminate or affect the
continued existence of rights created under Awards issued hereunder and
outstanding on November 28, 2005 which by their terms extend beyond such date.

                                  SECTION 12
                             Shareholder Approval
                             --------------------

          This Plan shall become effective on November 29, 1995 (the date the
Plan was adopted by the Board); provided, however, that if the Plan is not
approved (i) by the written consent of the holders of at least a majority of the
shares of the Company entitled to vote, or (ii) by the affirmative vote of the
holders of at least a majority of the shares present, or represented, and
entitled to vote at a duly held meeting of the shareholders of the Company,
within 12 months after said date, the Plan and all Awards granted hereunder
shall be null and void and no additional Awards shall be granted hereunder.

                                  SECTION 13
                                 Miscellaneous
                                 -------------

          (a)  Governing Law. The Plan, and the Option Agreements and Restricted
               -------------
Stock Award Agreements (collectively the "Award Agreements") entered into, and
the Awards granted thereunder, shall be governed by the Code provisions to the
extent applicable.  Otherwise, the operation of, and the rights of Eligible
Individuals under, the Plan, the Award Agreements, and the Awards shall be
governed by applicable federal law and otherwise by the laws of the State of New
York.

          (b)  Rights.  Neither the adoption of the Plan nor any action of the
               ------
Board or the Committee shall be deemed to give any individual any right to be
granted an Award, or any other right hereunder, unless and until the Committee
shall have granted such individual an Award, and then his rights shall be only
such as are provided by the Plan and the Award Agreement.

                                      12
<PAGE>

          Any Option under the Plan shall not entitle the holder thereof to any
rights as a shareholder of the Company prior to the exercise of such Option and
the issuance of the shares pursuant thereto.  Further, notwithstanding any
provisions of the Plan or any Award Agreement with a Grantee, but subject to any
employment agreement or consulting agreement, the Company shall have the right,
in its discretion, to retire an Employee at any time pursuant to its retirement
rules or otherwise to terminate his employment or a Consultant's consulting
services at any time for any reason whatsoever.

          (c)  No Obligation to Exercise Option. The granting of an Option shall
               --------------------------------
impose no obligation upon a Grantee to exercise such Option.

          (d)  Non-Transferability.  Except as otherwise provided in any Award
               -------------------
Agreement, no Award shall be assignable or transferable by the Grantee otherwise
than by will or by the laws of descent and distribution, and during the lifetime
of the Grantee, any Options shall be exercisable only by him or by his guardian
or legal representative.  If a Grantee is married at the time of exercise of an
Option and if the Grantee so requests at the time of exercise, the certificate
or certificates issued shall be registered in the name of the Grantee and the
Grantee's spouse, jointly, with right of survivorship.

          (e)  Listing and Registration of Shares.  Each Award shall be subject
               ----------------------------------
to the requirement that, if at any time the Committee shall determine, in its
discretion, that the listing, registration, or qualification of the Common
Shares covered thereby upon any securities exchange or under any state or
federal law, or the consent or approval of any governmental regulatory body, is
necessary or desirable as a condition of, or in connection with, the granting of
such Award or the purchase or vesting of Common Shares thereunder, or that
action by the Company or by the Grantee should be taken in order to obtain an
exemption from any such requirement, no such Option may be exercised, in whole
or in part, and no Common Shares shall be received pursuant to a Restricted
Stock Award, unless and until such listing, registration, qualification,
consent, approval, or action shall have been effected, obtained, or taken under
conditions acceptable to the Committee.  Without limiting the generality of the
foregoing, each Grantee or his legal representative or beneficiary may also be
required to give satisfactory assurance that shares purchased upon exercise of
an Option or received pursuant to a Restricted Stock Award are being purchased
for investment and not with a view to distribution, and certificates
representing such shares may be legended accordingly.

          (f)  Withholding and Use of Shares to Satisfy Tax Obligations.  The
               --------------------------------------------------------
obligation of the Company to deliver Common Shares pursuant to any Award (or
cash in lieu thereof) shall be subject to any applicable federal, state or local
tax withholding requirements.

          In connection with an Award in the form of Common Shares subject to
the withholding requirements of applicable federal tax law, the Committee, in
its discretion (and subject to any withholding rules adopted by the Committee),
may permit the Employee to satisfy the minimum required federal, state and local
withholding tax, in whole or in part, by electing to have the Company withhold
Common Shares subject to the exercise (or by returning previously acquired
Common Shares to the Company). Common Shares shall be

                                      13
<PAGE>

valued, for purposes of this paragraph, at their Fair Market Value on the date
the amount attributable to the Restricted Stock Award, or the exercise of the
Option, is includable in income by the Grantee under section 83 of the Code (the
"Determination Date").

          If Common Shares acquired by the exercise of an ISO are used to
satisfy the withholding requirement described above, such Common Shares must
have been held by the Employee for a period of not less than the holding period
described in section 422(a) (1) of the Code as of the Determination Date.  If
Common Shares acquired by the exercise of an NQSO or of an option under a
similar plan are used to satisfy such withholding requirement with regard to an
Officer or a director of the Company, such option must have been granted to the
Officer or director at least 6 months prior to the Determination Date.

          The Committee shall adopt such withholding rules as it deems necessary
to carry out the provisions of this paragraph.

          (g)  Indemnification of Board and Committee.  Without limiting any
               --------------------------------------
other rights of indemnification which they may have from the Company and any
Related Corporation, the members of the Board and the members of the Committee
shall be indemnified by the Company against all costs and expenses reasonably
incurred by them in connection with any claim, action, suit, or proceeding to
which they or any of them may be a party by reason of any action taken or
failure to act under, or in connection with, the Plan, or any Award granted
thereunder, and against all amounts paid by them in settlement thereof (provided
such settlement is approved by legal counsel selected by the Company) or paid by
them in satisfaction of a judgment in any such action, suit, or proceeding,
except a judgment based upon a finding of willful misconduct or recklessness on
their part.  Upon the making or institution of any such claim, action, suit, or
proceeding, the Board or Committee member shall notify the Company in writing,
giving the Company an opportunity, at its own expense, to handle and defend the
same before such Board or Committee member undertakes to handle it on his own
behalf.

          (h)  Application of Funds.  The proceeds received by the Company from
               --------------------
the sale of Common Shares pursuant to Awards granted under the Plan shall be
used for general corporate purposes.  Any cash received in payment for shares
upon exercise of an Option to purchase Common Shares or vesting of a Restricted
Stock Award shall be added to the general funds of the Company and shall be used
for its corporate purposes.  Any Common Shares received in payment for shares
upon exercise of an Option or vesting of a Restricted Stock Award shall become
treasury stock.

                                      14
<PAGE>

ISO-000                                                                   Shares

                            ORCHID BIOCOMPUTER, INC.
                            1995 Stock Incentive Plan
                       Incentive Stock Option Certificate

         Orchid Biocomputer, Inc. (the "Company"), a Delaware corporation,
hereby grants to the person named below an option to purchase shares of Common
Stock, $0.001 par value, of the Company (the "Option") under and subject to the
Company's 1995 Stock Incentive Plan (the "Plan") exercisable on the following
terms and conditions and those set forth on the reverse side of this
certificate:

Name of Optionholder:
Address:

Number of Shares:
Exercise Price per Share:
Date of Grant:

Vesting Schedule:         The shares subject to this option certificate shall
                          vest monthly on the last day of each month in forty-
                          eight (48) equal installments of 2.083% per month over
                          a period of four (4) years from the effective date of
                          this certificate, with the first such vesting to occur
                          on _______________________.

Expiration Date:

         This Option is intended to be treated as an Incentive Stock Option
under section 422 of the Internal Revenue Code of 1986, as amended (the "Code").

         By acceptance of this Option, the Optionholder agrees to the terms and
conditions hereof.

                                 ORCHID BIOCOMPUTER, INC.

                                 By:
                                    ---------------------------------------

                                       15
<PAGE>

               ORCHID BIOCOMPUTER, INC. 1995 STOCK INCENTIVE PLAN

                   INCENTIVE STOCK OPTION TERMS AND CONDITIONS
                   -------------------------------------------

         1. Plan Incorporated by Reference. This Option is issued pursuant to
            ------------------------------
the terms of the Plan and may be amended as provided in the Plan. Capitalized
terms used and not otherwise defined in this certificate have the meanings given
to them in the Plan. This certificate does not set forth all of the terms and
conditions of the Plan, which are incorporated herein by reference. The
Committee administers the Plan, and its determinations regarding the operation
of the Plan are final and binding. Copies of the Plan may be obtained upon
written request without charge from the Human Resources Department of the
Company.

         2. Option Price. The price to be paid for each share of Common Stock
            ------------
issued upon exercise of the whole or any part of this Option is the Option Price
set forth on the face of this certificate.

         3. Exercisability Schedule. This Option may be exercised at any time
            -----------------------
and from time to time for the number of shares and in accordance with the
Schedule set forth on the face of this certificate, but only for the purchase of
whole shares. This Option may not be exercised as to any shares after the
Expiration Date.

         4. Method of Exercise. To exercise this Option, the Optionholder shall
            ------------------
deliver written notice of exercise to the Company specifying the number of
shares with respect to which the Option is being exercised accompanied by
payment of the Option Price for such shares in cash, by certified check or in
such other form, including shares of Common Stock of the Company valued at their
fair market value on the date of delivery, as the Committee may approve.
Promptly following such notice, the Company will deliver to the Optionholder a
certificate representing the number of shares with respect to which the Option
is being exercised. In connection with any purchase of shares pursuant to an
exercise of this option, the Optionholder shall exercise a Stock Restriction
Agreement in form and substance reasonably acceptable to the Company.

         5. Rights as a Stockholder or Employee. The Optionholder shall not have
            -----------------------------------
any rights in respect of shares as to which the Option shall not have been
exercised and payment made as provided above. The Optionholder shall not have
any rights to continued employment by the Company or its Affiliates by virtue of
the grant of this Option.

         6. Recapitalization, Mergers, Etc. As provided in the Plan, in the
            ------------------------------
event of corporate transactions affecting the Company's outstanding Common
Stock, the Committee shall equitably adjust the number and kind of shares
subject to this Option and the exercise price hereunder or make provision for a
cash payment. If such transaction involves a consolidation or merger of the
Company with another equity, the sale or exchange of all or substantially all of
the assets of the Company or a reorganization or liquidation of the Company,
then in lieu of the foregoing, the Committee may upon written notice to the
Optionholder provide that this Option shall terminate on a date not less than 20
days after the date of such notice unless theretofore exercised. In connection
with such notice, the Committee may in its discretion accelerate or waive any
deferred exercise period.

         7. Option Not Transferable. This Option is not transferable by the
            -----------------------
Optionholder otherwise than by will or the laws of descent and distribution, and
is exercisable, during the Optionholder's lifetime, only by the Optionholder.
The naming of a Designated Beneficiary does not constitute a transfer.

         8. Exercise of Option After Termination of Employment. If the
            --------------------------------------------------
Optionholder's employment with (a) the Company, (b) an Affiliate, or (c) a
corporation (or parent or subsidiary corporation of such corporation) issuing or
assuming a stock option in a transaction to which section 424(a) of the Code
applies, is terminated for any reason other than by disability (within the
meaning of section 22(e)(3) of the Code) or death, the Optionholder may exercise
the rights which were available to the Optionholder at the time of such
termination only within three months from the date of termination. If
Optionholder's employment is terminated as a result of disability, such rights
may be exercised within twelve months from the date of termination. Upon the
death of the Optionholder, his or her Designated Beneficiary shall have the
right, at any time within twelve months after the date of death, to exercise in
whole or in part any rights that were available to the Optionholder at the time
of death. Notwithstanding the foregoing, no rights under this Option may be
exercised after the Expiration Date.

         9. Compliance with Securities Laws. It shall be a condition to the
            -------------------------------
Optionholder's right to purchase shares of Common Stock hereunder that the
Company may, in its discretion, require (a) that the shares of Common Stock
reserved for issue upon the exercise of this Option shall have been duly listed,
upon official notice of issuance, upon any national securities exchange or
automated quotation system on which the Company's Common Stock may then be
listed or quoted, (b) that either (i) a registration statement under the
Securities Act of 1933, as amended (the "Act") with respect to the shares shall
be in effect, or (ii) in the option of counsel for the Company, the proposed
purchase shall be exempt from registration under that Act and the Optionholder
shall have made such undertakings and agreements with the Company as the Company
may reasonably require, and (c) that such other steps, if any, as counsel for
the company shall consider necessary to comply with any law applicable to the
issue of such shares by the Company shall have been taken by the Company or the
Optionholder, or both. The certificates representing the shares purchased under
this Option may contain such legends as counsel for the Company shall consider
necessary to comply with any applicable law.

         10. Payment of Taxes. The Optionholder shall pay to the Company, or
             ----------------
make provision satisfactory to the Company for payment of, any taxes required by
law to be withheld with respect to the exercise of this Option. The Committee
may, in its discretion, require any other Federal or state taxes imposed on the
sale of the shares to be paid by the Optionholder. In the Committee's
discretion, such tax obligations may be paid in whole or in part in shares of
Common Stock, including shares retained from the exercise of this Option, valued
at their fair market value on the date of delivery. The Company and its
Affiliates may, to the extent permitted by law, deduct any such tax obligations
from any payment of any kind otherwise due to the Optionholder.

         11. Notice of Sale of Shares Required. The Optionholder agrees to
             ---------------------------------
notify the Company in writing within 30 days of the disposition of any shares
purchased upon exercise of this Option if such disposition occurs within two
years of the date of the grant of this Option or within one year after such
purchase.

                                       16
<PAGE>

NSO-000                                                                   Shares

                            ORCHID BIOCOMPUTER, INC.
                            1995 Stock Incentive Plan
                     Non-Statutory Stock Option Certificate

         Orchid Biocomputer, Inc. (the "Company"), a Delaware corporation,
hereby grants to the person named below an option to purchase shares of Common
Stock, $0.001 par value, of the Company (the "Option") under and subject to the
Company's 1995 Stock Incentive Plan (the "Plan") exercisable on the following
terms and conditions and those set forth on the reverse side of this
certificate:

Name of Optionholder:
Address:

Number of Shares:
Exercise Price per Share:
Date of Grant:

Vesting Schedule:     The shares subject to this option certificate shall vest
                      monthly on the last day of each month in (_) equal
                      installments of ____ per month over a period of ____
                      (_) years from the effective date of this certificate,
                      with the first such vesting to occur on _________________.

Expiration Date:

         By acceptance of this Option, the Optionholder agrees to the terms and
conditions hereof.

                                     ORCHID BIOCOMPUTER, INC.

                                     By:
                                        ---------------------------------------

                                       17
<PAGE>

               ORCHID BIOCOMPUTER, INC. 1995 STOCK INCENTIVE PLAN

                 NON-STATUTORY STOCK OPTION TERMS AND CONDITIONS
                 -----------------------------------------------

         1. Plan Incorporated by Reference. This Option is issued pursuant to
            ------------------------------
the terms of the Plan and may be amended as provided in the Plan. Capitalized
terms used and not otherwise defined in this certificate have the meanings given
to them in the Plan. This certificate does not set forth all of the terms and
conditions of the Plan, which are incorporated herein by reference. The
Committee administers the Plan, and its determinations regarding the operation
of the Plan are final and binding. Copies of the Plan may be obtained upon
written request without charge from the Human Resources Department of the
Company.

         2. Option Price. The price to be paid for each share of Common Stock
            ------------
issued upon exercise of the whole or any part of this Option is the Option Price
set forth on the face of this certificate.

         3. Exercisability Schedule. This Option may be exercised at any time
            -----------------------
and from time to time for the number of shares and in accordance with the
Schedule set forth on the face of this certificate, but only for the purchase of
whole shares. This Option may not be exercised as to any shares after the
Expiration Date.

         4. Method of Exercise. To exercise this Option, the Optionholder shall
            ------------------
deliver written notice of exercise to the Company specifying the number of
shares with respect to which the Option is being exercised accompanied by
payment of the Option Price for such shares in cash, by certified check or in
such other form, including shares of Common Stock of the Company valued at their
fair market value on the date of delivery, as the Committee may approve.
Promptly following such notice, the Company will deliver to the Optionholder a
certificate representing the number of shares with respect to which the Option
is being exercised. In connection with any purchase of shares pursuant to an
exercise of this option, the Optionholder shall exercise a Stock Restriction
Agreement in form and substance reasonably acceptable to the Company.

         5. Rights as a Stockholder or Employee. The Optionholder shall not have
            -----------------------------------
any rights in respect of shares as to which the Option shall not have been
exercised and payment made as provided above. The Optionholder shall not have
any rights to continued employment by the Company or its Affiliates by virtue of
the grant of this Option.

         6. Recapitalization, Mergers, Etc. As provided in the Plan, in the
            ------------------------------
event of corporate transactions affecting the Company's outstanding Common
Stock, the Committee shall equitably adjust the number and kind of shares
subject to this Option and the exercise price hereunder or make provision for a
cash payment. If such transaction involves a consolidation or merger of the
Company with another equity, the sale or exchange of all or substantially all of
the assets of the Company or a reorganization or liquidation of the Company,
then in lieu of the foregoing, the Committee may upon written notice to the
Optionholder provide that this Option shall terminate on a date not less than 20
days after the date of such notice unless theretofore exercised. In connection
with such notice, the Committee may in its discretion accelerate or waive any
deferred exercise period.

         7. Option Not Transferable. This Option is not transferable by the
            -----------------------
Optionholder otherwise than by will or the laws of descent and distribution, and
is exercisable, during the Optionholder's lifetime, only by the Optionholder.
The naming of a Designated Beneficiary does not constitute a transfer.

         8. Exercise of Option After Termination of Employment. If the
            --------------------------------------------------
Optionholder's status as an employee, consultant or director of (a) the Company,
(b) an Affiliate, or (c) a corporation (or parent or subsidiary corporation of
such corporation) issuing or assuming a stock option in a transaction to which
section 424(a) of the Code applies, is terminated for any reason other than by
disability (within the meaning of section 22(e)(3) of the Code) or death, the
Optionholder may exercise the rights which were available to the Optionholder at
the time of such termination only within three months from the date of
termination. If such status is terminated as a result of disability, such rights
may be exercised within twelve months from the date of termination. Upon the
death of the Optionholder, his or her Designated Beneficiary shall have the
right, at any time within twelve months after the date of death, to exercise in
whole or in part any rights that were available to the Optionholder at the time
of death. Notwithstanding the foregoing, no rights under this Option may be
exercised after the Expiration Date.

         9. Compliance with Securities Laws. It shall be a condition to the
            -------------------------------
Optionholder's right to purchase shares of Common Stock hereunder that the
Company may, in its discretion, require (a) that the shares of Common Stock
reserved for issue upon the exercise of this Option shall have been duly listed,
upon official notice of issuance, upon any national securities exchange or
automated quotation system on which the Company's Common Stock may then be
listed or quoted, (b) that either (i) a registration statement under the
Securities Act of 1933, as amended (the "Act") with respect to the shares shall
be in effect, or (ii) in the option of counsel for the Company, the proposed
purchase shall be exempt from registration under that Act and the Optionholder
shall have made such undertakings and agreements with the Company as the Company
may reasonably require, and (c) that such other steps, if any, as counsel for
the company shall consider necessary to comply with any law applicable to the
issue of such shares by the Company shall have been taken by the Company or the
Optionholder, or both. The certificates representing the shares purchased under
this Option may contain such legends as counsel for the Company shall consider
necessary to comply with any applicable law.

         10. Payment of Taxes. The Optionholder shall pay to the Company, or
             ----------------
make provision satisfactory to the Company for payment of, any taxes required by
law to be withheld with respect to the exercise of this Option. The Committee
may, in its discretion, require any other Federal or state taxes imposed on the
sale of the shares to be paid by the Optionholder. In the Committee's
discretion, such tax obligations may be paid in whole or in part in shares of
Common Stock, including shares retained from the exercise of this Option, valued
at their fair market value on the date of delivery. The Company and its
Affiliates may, to the extent permitted by law, deduct any such tax obligations
from any payment of any kind otherwise due to the Optionholder.

         11. Notice of Sale of Shares Required. The Optionholder agrees to
             ---------------------------------
notify the Company in writing within 30 days of the disposition of any shares
purchased upon exercise of this Option if such disposition occurs within two
years of the date of the grant of this Option or within one year after such
purchase.

                                       18<PAGE>

                                                                    Exhibit 10.4

     THIS LEASE is made this 6th day of March, 1998, between COLLEGE ROAD
ASSOCIATES, LIMITED PARTNERSHIP, having an office at 2 Research Way, Princeton
NJ 08540, hereinafter called "Landlord", and Orchid Biocomputer Inc. with an
office located at 303 College Road East, Princeton, New Jersey 08540,
hereinafter called `Tenant".

                               LEASE OF PREMISES

     Landlord hereby leases to Tenant and Tenant hereby hires from Landlord,
subject to all of the terms and conditions hereinafter set forth, those certain
premises (the "Premises") as set forth in Items 1 of the Basic Lease Provisions
and as shown in the drawings attached hereto as Exhibit "A" being located on the
floor indicated in that certain office building (the "Building") and on that
certain lot (the "Parcel") together hereinafter referred to as (the "Project")
being located at 303 College Road East, Township of Plainsboro, County of
Middlesex, State of New Jersey.

                            BASIC LEASE PROVISIONS

1.   Location of Premises:                 303 College Road East
                                           Princeton, New Jersey 08540

2.   Rentable Area of Premises:            30,894 rentable square feet
                                           (28,085 usable s.f. x 1.10
                                           = 30,894 rentable s.f.)
3.   Tenant's Percentage Share:            50.35% (30,894/61,359)
4.   Base Project Operating Expenses:      Those incurred in the year 1999
5.   Base Project Property Taxes:          Those incurred in the year 1999
6.   Basic Annual Rent:                    Years 1-5 @ $695,115.00 per annum
                                           ($22.50 psf) + all electric; and
                                           Years 6-10 @ $726,009.00 per annum
                                           ($23.50 psf) + all electric
7.   Basic Monthly Rental Installments:    Months 1-60 @ $57,926.25 per month
                                           + all electric; and
                                           Months 61-120 @ $60,500.75 per month
                                           + all electric
8.   Term:                                 Ten (10) years
9.   Target Commencement Date:             January 1, 1999
10.  Security Deposit:                     $115,852.50 + a Letter of Credit in
                                           the amount of $600,000.00 (see
                                           Paragraph 4)
11.  Parking Spaces:                       124
12.  Broker(s):                            Grubb & Ellis Company
13.  Permitted Use:                        General Office, Development, Light
                                           Assembly and R & D Laboratory
<PAGE>

14.  Addresses for Notices:
               LANDLORD                                                TENANT
     College Road Associates,                       Orchid Biocomputer, Inc.
     Limited Partnership                            303 College Road East
     2 Research Way                                 Princeton, New Jersey 08540
     Princeton, NJ 08540

15.  All payments under this Lease shall be payable and sent to:

                            College Road Associates
                                2 Research Way
                          Princeton, New Jersey 08540

           or such other payee or address as Landlord may designate.

     IN WITNESS WHEREOF, the parties hereto have executed this Lease, consisting
of the foregoing and Paragraphs I through 48 which follow, together with
Exhibits A through F inclusive, incorporated herein by this reference as of the
date first above written.

                              College Road Associates,
                              Limited Partnership

                              By:    Z Forrestal Center, L.P.,
                                     Managing General Partner

                              By:    Z Forrestal Corp.,
                                     General Partner

                              By:    /s/ John Zirinsky
                                     ---------------------------------
                              Name:  John Zirinsky
                              Title: President

                              Orchid Biocompter, Inc.

                              By:    /s/ Dale R. Pfost, Ph.D.
                                     ---------------------------------
                              Name:  Dale R. Pfost, Ph.D.
                              Title: Chairman, President and CEO

                                       2
<PAGE>

STATE OF NEW YORK:
                         :ss
COUNTY OF NEW YORK:

     BE IT REMEMBERED, that on this 10th day of March, 1998, before me, the
subscriber, a Notary Public of the State of New York personally appeared John
Zirinsky, of Z Forrestal Corp., the General Partner of Z Forrestal Center, L.P.,
the General Partner of College Road Associates, Limited Partnership, who, I am
satisfied, is the person who has signed the within instrument, and he did
acknowledge that he signed, sealed and delivered the same as such officer
aforesaid; and that the within instrument is the voluntary act and deed of said
corporation made by virtue of authority from its Board of Directors.

                              /s/ Marc L. Dececchis
                              --------------------------------------------

                                      MARC L. DeCECCHIS
                                  Notary Public, State of New York
                                         No. 4963923
                                  Qualified in Westchester County
                                  Commission Expires  3/19/1998

STATE OF NEW YORK:
                         :ss
COUNTY OF NEW YORK:

     BE IT REMEMBERED, that on this 6th day of March, 1998, before me, the
subscriber, a Notary Public of the State of New Jersey personally appeared Dale
R. Pfost, Ph.D., president of Orchid Biocomputer, Inc., who, I am satisfied, is
the person who has signed the within instrument, and he did acknowledge that he
signed, sealed and delivered the same as such officer aforesaid; and that the
within instrument is the voluntary act and deed of said corporation made by
virtue of authority from its Board of Directors.

                              /s/ Debra H. Babashak
                              --------------------------------------------

                                     DEBRA H. BABASHAK
                                 NOTARY PUBLIC OF NEW JERSEY
                              MY COMMISSION EXPIRES AUGUST 12 2001

                                       3
<PAGE>

                               TABLE OF CONTENTS

<TABLE>
<CAPTION>
    PARAGRAPH                                                             PAGE
<S>                                                                       <C>

1.   Commencement Date and Term                                           6
2.   Basic Annual Rent                                                    6
3.   Additional Rent                                                      7-11
4.   Security Deposit                                                     11
5.   Repairs                                                              12
6.   Improvements and Alterations                                         12-14
7.   Liens                                                                14
8.   Use of Premises                                                      14-16
9.   Utilities and Services                                               16-18
10.  Rules and Regulations                                                19
11.  Taxes on Tenant's Property                                           19
12.  Substituted Premises                                                 19
13.  Fire and Casualty                                                    20
14.  Eminent domain                                                       20-21
15.  Assignment and Subletting                                            21-22
16.  Landlord's Access to Premises                                        22-23
17.  Subordination:  Attornment; Estoppel Certificates                    23
18.  Sale by Landlord                                                     24
19.  Indemnification of Landlord and Insurance                            24-26
20.  Waiver of Subrogation                                                26
21.  No Waiver                                                            26
22.  Default                                                              27-29
23.  Right of Landlord to Cure Tenant's Default                           29-30
24.  Notices                                                              30
25.  Insolvency or Bankruptcy                                             30
26.  Surrender and Holdover                                               30-31
27.  Condition of Premises                                                31
28.  Quiet Possession                                                     31
29.  Limitation of Landlord's Liability                                   31-32
30.  Governing Law                                                        32
31.  Common Facilities                                                    32
32.  Successors and Assigns                                               33
33.  Brokers                                                              33
34.  Name                                                                 34
35.  Examination of Lease                                                 34
36.  Additional Charges                                                   34
37.  Marginal Headings                                                    34
38.  Prior Agreements; Severability                                       35
39.  Parking                                                              35
40.  Authority                                                            35
41.  No Light, Air or View Easement                                       35
42.  Force Majeure                                                        36
43.  Attornment                                                           36
</TABLE>

                                       4
<PAGE>

<TABLE>
<S>                                                                      <C>
44.  Common Area Maintenance Cost                                        36
45.  Notice Regarding Tenant's Move In or Out                            37
46.  Option to Expand First Available Space                              37-38
47.  First Option to Renew                                               38
48.  Second Option to Renew                                              38
</TABLE>

          Exhibit "A"         Floor Plans
          Exhibit "B1"        Landlord's Work Letter
          Exhibit "B2"        Building Standard Work Letter
          Exhibit "C"         Commencement Date Memorandum
          Exhibit "D"         Rules and Regulations
          Exhibit "E"         Janitorial Specifications
          Exhibit "F"         Model Letter of Credit

                                       5
<PAGE>

                          COMMENCEMENT DATE AND TERM

                                  PARAGRAPH 1

     (A)  The term of this Lease shall be as shown in Item 8 of the Basic Lease
Provisions and shall commence on the Target Commencement Date as shown in Item 9
of the Basic Lease Provisions or such earlier date as a Temporary Certificate of
Occupancy has been issued. Such date of commencement, hereinafter the
"Commencement Date", shall be confirmed by Landlord and Tenant by execution of a
"Commencement Date Memorandum" in a form substantially similar to Exhibit "C".

     (B)  Notwithstanding the Commencement Date, if for any reason Landlord
cannot deliver possession of the Demised Premises to Tenant on said Commencement
Date, then Landlord shall not be subject to any liability therefor; nor shall
such failure affect the validity of this Lease or the obligations of Tenant
hereunder, provided that Tenant shall not be obligated to pay Rent (except a sum
equal to the first Basic Monthly Rental Installment) until possession of the
Premises is rendered to Tenant.

                               BASIC ANNUAL RENT

                                  PARAGRAPH 2

     (A)  Tenant agrees to pay as Basic Annual Rent for the Premises the initial
sum shown in Item 6 of the Basic Lease Provisions. Except for months when this
Lease is not in effect for the full calendar month (partial month), the Basic
Annual Rent shall be payable in U.S. currency in equal monthly installments,
hereinafter sometimes referred to as "Basic Monthly Rental Installments", in
advance without notice, deduction, demand, offset, or abatement. Basic Monthly
Rental Installments shall be in the initial sum shown in Item 7 of the Basic
Lease Provisions. Payment of Basic Annual Rent shall commence on the
Commencement Date (except that the first month's rent shall be due upon the
signing of this Lease), and continue on the first day of each calendar month
thereafter except that Basic Rent for any partial month during the term hereof
shall be prorated in the proportion that the number of days this lease is in
effect during such partial month bears to the number of days in that calendar
month, and shall be paid at the commencement of such partial month, and except
further that the Basic Monthly Rental Installment for the first full calendar
month of this Lease for which an installment of Basic Annual Rent is due will be
paid on execution hereof.

     (B)  In addition to the Basic Annual Rent stipulated herein, Tenant
covenants and agrees to pay Landlord without offset or deduction as additional
Rent, hereinafter "Additional Rent", all other sums and charges which are to be
paid by Tenant pursuant to the terms of this Lease. Except as otherwise provided
in this Lease, Additional Rent shall be due and payable on the first day of the
month following the date on which Tenant is given notice that Additional Rent is
due. Rent means Basic Annual Rent and Additional Rent.

                                       6
<PAGE>

                                ADDITIONAL RENT

                                  PARAGRAPH 3

     (A)  For each calendar year during the term of this Lease, Tenant agrees to
pay as items of Additional Rent for the Premises, Tenant's "Percentage Share"
(being the percentage indicated in Item 3 of Basic Lease Provisions) of all
increases in "Project Operating Expenses" and "Project Property Taxes" (as
hereinafter defined) incurred by Landlord in the operation of the Building or
Project over the Base Project Operating Expenses and Base Project Property Taxes
as stipulated in Items 4 and 5 respectively in the Basic Lease Provisions.

     (B)  The items of Additional Rent contemplated under subparagraph 3(A)
shall be calculated in accordance with the following procedures:

          (i)   Each December during the term hereof or as soon thereafter as
                practical, Landlord shall give Tenant written notice of
                Landlord's estimate of any amounts payable under subparagraph
                3(A) above for the ensuing calendar year. On or before the first
                day of each month during the ensuing calendar year, Tenant shall
                pay Landlord without further notice 1/12 (One-twelfth) of such
                estimated amounts, provided that if such notice is not given in
                December, Tenant shall continue to pay on the basis of the then
                applicable rental until the month after such notice is given. If
                at any time or times it appears to Landlord that the adjusted
                amounts payable under subparagraph 3(A) for the current calendar
                year will exceed its estimate, Landlord may, by notice to
                Tenant, revise its estimate for such year. Subsequent payments
                by Tenant for such year shall be based upon such revised
                estimate.

          (ii)  Within ninety (90) days after the close of each calendar year or
                as soon thereafter as is practical, Landlord shall deliver to
                Tenant a statement of the annual adjustment of those Additional
                Rent items made pursuant to subparagraph 3(A) for such calendar
                year. If on the basis of such statement Tenant owes an amount
                that is less than the estimated payments for such calendar year
                previously made by Tenant, Landlord shall refund or credit such
                excess to Tenant. If on the basis of such statement Tenant owes
                an amount that is more than the estimated payment for such
                calendar year previously made by Tenant, Tenant shall pay the
                deficiency to Landlord within thirty (30) days after delivery of
                the statement.

          (iii) The Additional Rent due under the terms and conditions of this
                Paragraph 3 shall survive termination of this Lease, shall be
                payable by Tenant without any setoff or deduction, and shall be
                computed by Landlord on a prorated basis for any period less
                than a full calendar year.

                                       7
<PAGE>

          (iv) Anything to the contrary contained in this Paragraph 3
               notwithstanding, if the average occupancy of the Building is less
               than ninety-five (95%) percent during the Base Year hereinafter
               defined, then Landlord shall make a determination ("Landlord's
               Determination") of what the Project Operating Expenses for such
               year would have been if during the entire year the average tenant
               occupancy of the Building were ninety-five (95%) percent.
               Landlord's Determination shall be binding and conclusive upon
               Tenant and shall for all purposes of this Lease be deemed to be
               the Project Operating Expenses for the Base Year. Landlord shall
               notify Tenant of Landlord's Determination within ninety (90) days
               following the last day of the Base Year. Thereafter, if for any
               subsequent calendar year beginning after the Commencement Date
               the average tenant occupancy of the Building is below ninety-five
               (95%) percent, the Project Operating Expenses for any such year
               shall be adjusted by Landlord to the amount that such Project
               Operating Expenses would have been if the average tenant
               occupancy during that year had been ninety-five (95%) percent.
               The term Base Year means the twelve (12) month period during
               which Base Project Operating expenses are calculated.

     (C)  Definitions:

          (i)  The term "Project Operating Expenses" as used herein shall
               (except as noted below), include all costs of operation and
               maintenance of the Project for each calendar year as determined
               by generally accepted accounting principles consistently applied.
               Project Operating Expenses shall, by way of illustration but not
               limitation, include water and sewer charges, insurance premiums,
               license, permit, and inspection fees, fuel, heat, light, power
               (except for electricity charged directly to the Premises and
               other rental space on the Project), steam, janitorial and
               security services, labor, salaries for owners' on-site personnel,
               air conditioning, landscaping maintenance and repair of the
               Building and driveways, parking structures and surface parking
               areas, ice and snow removal, supplies, materials, equipment,
               tools, property management fees, office costs, and the cost
               incurred in contesting the validity of Project Property Taxes.
               Project Operating Expenses shall also include but not be limited
               to the cost of any capital improvements made to the Building by
               Landlord that reduce Project Operating Expenses or that are
               required under any governmental law or regulation not previously
               applicable to the Building or not in effect at the time it was
               constructed. Such capital cost shall be amortized over such
               reasonable periods as Landlord shall determine with a return on
               capital at the then current prime interest rate of the largest
               national bank in New York City or at such higher rate as may have
               been paid by Landlord on the funds borrowed for the purpose of
               purchasing such capital improvements. In no event shall Project
               Operating Expenses ever be

                                       8
<PAGE>

               less than Base Project Operating Expenses stipulated in Item 4 of
               Basic Lease Provisions.

          (ii) The term "Project Property Taxes" as used herein shall include
               all real estate taxes or personal property taxes and other taxes,
               charges and assessments, unforeseen as well as foreseen, which
               are levied with respect to the Project and any improvements,
               fixtures and equipment and other property of Landlord, real or
               personal, located in the Building or on the Project and used in
               connection with the operation of the Project for each calendar
               year and shall include any tax, surcharge or assessment which
               shall be levied in addition to or in lieu of real estate or
               personal property taxes, other than taxes covered in Paragraph
               11, and shall also include any rental, excise, sales,
               transaction, privilege, or other tax or levy, however,
               denominated, imposed upon or measured by the rental reserved
               hereunder or on Landlord's business of leasing the Premises and
               Project, excepting only net income taxes. In no event shall
               Project Property Taxes ever be less than Base Project Property
               taxes stipulated in Item 5 of Basic Lease Provisions.

     (D)  Unless Tenant takes written exception to any item in the statement
referred to in subparagraph 3(B)(ii) within thirty (30) days after the
furnishing of the statement, such statement shall be considered as final and
accepted by Tenant. Any amount due Landlord as shown on any such statement shall
be paid by Tenant within thirty (30) days after it is furnished to Tenant. If
Tenant shall dispute in writing any specific item, or items in the statement of
Project Operating Expenses and Project Property Taxes, and such dispute is not
resolved between Landlord and Tenant within sixty (60) days after the date the
statement was rendered, either party may, during the thirty (30) days next
following the expiration of the sixty (60) days, refer such disputed item or
items to any independent certified public accountant selected by Landlord, for a
determination. Pending the determination of any dispute with respect to the
statement submitted by Landlord, Tenant shall pay when due the sums shown as due
on such statement. If it shall be determined that any portion of such sums were
not properly chargeable to Tenant, then Landlord shall credit or refund the
appropriate sum to Tenant. The costs for the accountant's review and
determination will be borne by Landlord if it is determined that Landlord's
original calculation of both Project Property Taxes and Project Operating
Expenses was in error by more than five (5%) percent, otherwise such costs will
be borne by Tenant.

     (E)  As one of the items of Additional Rent, payable monthly, Tenant shall
also pay to Landlord the full cost of Tenant's consumption of electricity as
determined in accordance with Paragraph 9.

     (F)  The Basic Annual Rent plus Additional Rent are sometimes collectively
referred to as "Rent".

     (G)  Notwithstanding anything to the contrary in the definition of "Project
Operating Expenses", Project Operating Expenses shall not include the following:

                                       9
<PAGE>

          (i)    Costs incurred by Landlord with respect to goods and services
                 (including utilities sold and supplied to tenants and occupants
                 of the Building) to the extent that Landlord is entitled to
                 reimbursement for such costs;

          (ii)   Costs incurred by Landlord for the repair of damage to the
                 Building to the extent that Landlord is reimbursed by insurance
                 proceeds;

          (iii)  Costs, including permit, license and inspection costs, incurred
                 with respect to the installation of tenant improvements made
                 for new tenants in the Building or incurred in renovating or
                 otherwise improving, decorating, painting or redecorating
                 vacant space for tenants or other occupants of the Building;

          (iv)   Depreciation and amortization, except as provided herein and
                 except on materials, tools, supplies and vendor-type equipment
                 purchased by Landlord to enable Landlord to supply services
                 Landlord might otherwise contract for with a third party where
                 such depreciation and amortization would otherwise have been
                 included in the charge for such third party's services, all as
                 determined in accordance with generally accepted accounting
                 principles, consistently applied;

          (v)    Leasing commissions in connection with prospective tenants or
                 other occupants of the Building;

          (vi)   Costs incurred by Landlord for alterations which are considered
                 capital improvements and replacements under generally accepted
                 accounting principles, consistently applied except those which
                 reduce Project Operating Expenses or that are required under
                 any governmental law or regulation not previously applicable to
                 the Building or not in effect at the time it was constructed;

          (vii)  Costs of capital nature, including, without limitation, capital
                 improvements, and capital tools, all as determined in
                 accordance with generally accepted accounting principles,
                 consistently applied except those which reduce Project
                 Operating Expenses or that are required under any governmental
                 law or regulation not previously applicable to the Building or
                 not in effect at the time it was constructed;

          (viii) Overhead and profit increment paid to Landlord or to
                 subsidiaries or affiliates of Landlord for services in the
                 Building to the extent the same exceeds the costs of such
                 services rendered by unaffiliated third parties on a
                 competitive basis except all direct billing invoices will
                 include 10% overhead and 10% profit;

          (ix)   Interest, points and fees on debt or amortization on any
                 mortgage or mortgages encumbering the Building or the land;

                                       10
<PAGE>

          (x)    All items and services for which Tenant or any other tenant in
                 the building reimburses Landlord or which Landlord provides
                 selectively to one or more tenants (other than Tenant) without
                 reimbursement;

          (xi)   Advertising and promotional expenditures; and

          (xii)  Electric power costs for which any tenant directly contracts
                 with the local public service company except for common area.

                               SECURITY DEPOSIT

                                  PARAGRAPH 4

     Tenant has paid or agrees to pay Landlord such sum(s) as are set forth in
Item 10 of the Basic Lease Provisions as security for the performance of the
terms hereof by Tenant. If Tenant defaults with respect to any provision of this
Lease, including but not limited to, the provisions relating to the payment of
Rent or the surrender of the Premises in accordance with the terms hereof upon
the termination of the Lease, Landlord may, but shall not be required to use,
apply or retain all or any part of the Letter of Credit for the payment of any
Rent or any other sum due from Tenant in default, or for the payment of any
other amount which Landlord may spend or become obligated to spend by reason of
Tenant's default or to compensate Landlord for any other loss or damage which
Landlord may suffer by reason of Tenant's default including, without limitation,
costs and attorneys' fees incurred by Landlord. In the event of bankruptcy or
other debtor-creditor proceeding against Tenant, such Letter of Credit shall be
deemed to have been applied first to the payment of Rent and other charges due
Landlord for all periods prior to filing of such proceedings. In addition to the
$115,852.50 of Security Deposit set forth in Item 10 of the Basic Lease
Provisions, Tenant shall post a Letter of Credit in the form of Exhibit "F" in
the amount of $600,000.00. Beginning on the third year (twenty-fifth month) of
this Lease, and at the beginning of each successive year thereafter, Tenant
shall deliver to Landlord a revised Letter of Credit with the face amount of
each such Letter adjusted such that for the third year of this Lease the amount
shall be $533,000.00, for the fourth year the amount shall be $466,000.00, for
the fifth year the amount shall be $400,000.00, for the sixth year the amount
shall be $333,000.00, for the seventh year the amount shall be $266,000.00, for
the eighth year the amount shall be $200,000.00, for the ninth year the amount
shall be $133,000.00, and for the tenth year the amount shall be $67,000.00
(such amount shall remain in effect as Security Deposit for ninety (90) days
following the last day of the term of this Lease). The Irrevocable Letter of
Credit must be renewed sixty (60) days prior to its expiration date for each
year of this Lease, and Landlord given notice of such renewal at least sixty
(60) days prior to the expiration date of the then existing Letter of Credit.
The Letter of Credit is further security for the Tenant's performance of the
terms of this Lease.

                                       11
<PAGE>

                                    REPAIRS

                                  PARAGRAPH S

     (A)  Subject to Paragraph 5(B), Landlord shall cause all necessary repairs
to be made to the exterior doors, windows, corridors and other common areas of
the Building and the Project and Landlord shall cause the Building and the
Project to be kept in a safe, clean and neat condition and shall use reasonable
efforts to keep all equipment used in common with other tenants (such as
elevators, plumbing, heating, air conditioning and similar equipment) in good
condition and repair. Except as provided in Paragraph 13 hereof, there shall be
no abatement of Rent and no liability of Landlord by reason of any injury to or
interference with Tenant's business arising from the making of any repairs,
alterations or improvements in or to any portion of the Building or the Project
or in or to fixtures, appurtenances and equipment therein or thereon.

     (B)  Tenant agrees that all repairs to the Premises not required above to
be made by Landlord and all decorating, remodeling, alteration and painting
required by Tenant during the term of this Lease, if approved by Landlord, shall
be made by Landlord at the sole cost and expense of Tenant. Tenant will pay for
any repairs to the Premises, the Building or the Project made necessary by any
negligence or willful acts or omissions of Tenant or its assignees, subtenants,
employees or their respective agents or other persons permitted in the Building
or on the Project by Tenant, or any of them, and Tenant will maintain the
Premises, and, upon termination of this Lease, will leave the Premises in a
safe, clean, neat and sanitary condition. Tenant has the right to seek
competitive bids to ensure that Landlord's pricing for such repairs is
comparable to that which is charged by other area office parks of the same level
of quality as the Project.

     (C)  Landlord shall maintain and repair all HVAC equipment for Tenant,
except that with respect to any major repair (ex.: compressors, etc...), Tenant
will pay to Landlord as Additional Rent the cost of such major repair which
shall be payable in equal monthly installments over the remaining life of the
Lease.

                         IMPROVEMENTS AND ALTERATIONS

                                  PARAGRAPH 6

     (A)  Landlord's sole construction obligation under this Lease is as set
forth in the Work Letter attached hereto as Exhibit "B-1" and incorporated
herein by reference.

     (B)  Landlord shall have the right at any time to change the arrangement
and/or location of entrances or passageways, doors and doorways, and corridors,
elevators, stairs, toilets, or other public parts of the Building or Project,
and upon giving Tenant reasonable notice thereof, to change the name, number or
designation by which the Building or the Project is commonly known.

                                       12
<PAGE>

     (C)  The alterations, additions or improvements to or of the Premises or
any part thereof referred to in this subparagraph (6)(C) do not include the
initial tenant improvements. Tenant shall not make or cause to be made any
alterations, additions or improvements to or of the Premises or any part
thereof, or attach any fixtures or equipment thereto, without first obtaining
Landlord's prior written consent (which consent shall not be unreasonably
withheld). Any such alterations, additions or improvements to the Premises
consented to by Landlord shall at Landlord's option be made by Landlord for
Tenant's account and Tenant shall pay Landlord for the costs thereof (including
reasonable charge for Landlord's overhead) within ten (10) days after receipt of
Landlord's statement. All such alterations, additions and improvements shall
(without compensation to Tenant) at Landlord's option become Landlord's property
(except movable furniture and trade fixtures) and at the end of the term hereof,
shall remain on the Premises unless Landlord elects by notice to Tenant to have
Tenant remove same, in which event Tenant shall promptly restore the Premises to
their condition prior to the installation of (i) such alterations, additions and
improvements, and (ii) equipment of any nature. Further, Landlord may elect by
notice to Tenant to have Tenant remove not only Tenant's alterations, additions
and improvements, but also any items of Tenant's equipment including but not
limited to movable furniture, trade fixtures, office equipment and any cafeteria
equipment. Any such equipment not removed from the Premises at the end of the
term hereof shall at the option of the Landlord become Landlord's property
without payment of any consideration therefor. The removal of any such equipment
and any alterations, additions and improvements which Landlord elects Tenant to
remove will be accomplished by Tenant prior to the expiration of the term of
this Lease and if not done, Tenant will be deemed a tenant at sufferance
pursuant to Paragraph 26. If Tenant does not perform such removal, Landlord may
remove, destroy, store or otherwise dispose of such alterations, additions,
improvements and equipment, whether or not Landlord takes title thereto. In
addition, Tenant will pay (i) all Landlord's costs of removing, disposing or
destroying any such alterations, additions, improvements and equipment whether
or not Landlord takes title thereto, that Tenant is supposed to remove, which
Tenant does not remove, and (ii) Landlord's cost to restore the Premises to
their condition prior to the installation of any alterations, additions,
improvements and equipment of any nature referred to in subdivision (i) of this
sentence. Such costs will include Landlord's fees and expenses in collecting
such costs and interest on such costs at the rate of fourteen (14%) percent per
annum. Tenant will pay to Landlord Landlord's costs of storage of any equipment
which Tenant is supposed to remove pursuant to this paragraph that Tenant does
not remove. Further, Landlord reserves and shall have right of access to the
Premises at any time within ninety (90) days prior to any projected termination
of this Lease to inspect the Premises to determine alterations, additions,
improvements and equipment Landlord desires Tenant to remove. This right of
access is in addition to Landlord's right of access set forth in Paragraph 16
hereof. Notwithstanding the above, Landlord and Tenant hereby agree that nine
(9) months prior to the expiration of the term of this Lease, Tenant will have
the right to either (i) leave all of the improvements and remove only its
furniture and trade fixtures, or (ii) remove any improvements (example: hood,
benches, coolers, etc...) in which event Tenant must remove all improvements and
restore the Premises to a shell condition at its sole cost and expense, prior to
the expiration of the term of this Lease. (Shell condition shall mean... demo
walls, floors, ceilings, cap utilities, remove all wiring back to distribution
panels, remove all data and telephone wiring completely, patch all holes in
walls, floors and roof, remove flex

                                       13
<PAGE>

ductwork to VAV boxes and leave the Premises in a safe condition to the then
current codes.

                                     LIENS

                                  PARAGRAPH 7

     Tenant shall keep the Premises `free from any liens arising out of any work
performed, materials furnished, or obligations incurred by or for Tenant. In the
event that Tenant shall not, within ten (10) days following the imposition of
any such lien, cause the same to be released of record by payment or posting of
a proper bond, Landlord shall have, in addition to all other remedies provided
herein or by law, the right but not the obligation, to cause the same to be
released by such means as it shall deem proper, including payment of or defense
against the claim giving rise to such lien. All sums paid by Landlord and all
expenses incurred by it in connection therewith, shall create automatically an
obligation of Tenant to pay an equivalent amount as Additional Rent, which
Additional Rent shall be payable by Tenant on Landlord's demand with interest at
the maximum rate per annum permitted by law until paid. For purposes of this
Paragraph 7, "liens" shall include, but not be limited to, lien claims filed
under the "Construction Lien Law".

     Notwithstanding any other provision of this Lease to the contrary, Tenant
shall have the right to finance the purchase of its personal property, fixtures
and equipment by lease or otherwise and the right to enter into security
agreements with respect thereto and any such lien created thereby shall be
superior to any rights of Landlord, if any, in said personal property, fixtures
or equipment created hereunder this Lease; provided, however, that in no event,
shall any such lien encumber the Premises, the Building or the Project.

                                USE OF PREMISES

                                  PARAGRAPH 8

     Tenant shall use the Premises only as set forth in Item 13 of the Basic
Lease Provisions and shall not use or permit the Premises to be used for any
other purpose without the prior written consent of Landlord. Tenant shall comply
with all laws and covenants and restrictions of record affecting use of the
Premises, and shall not use or occupy the Premises in violation of law or of the
certificate of occupancy issued for the Building, and shall immediately
discontinue any use of the Premises which is declared by any governmental
authority having jurisdiction to be a violation of law or of said certificate of
occupancy. Tenant shall comply with any direction of any governmental authority
having jurisdiction which shall, by reason of the nature of Tenant's use or
occupancy of the Premises impose any duty upon Tenant or Landlord with respect
to the Premises or with respect to the use or occupancy thereof. Tenant shall
not do or permit to be done anything which will invalidate or increase the cost
of any fire, extended coverage or any other insurance policy covering the
Building, the Project and/or property located therein and shall comply with all
rules, orders, regulations and requirements of the appropriate fire

                                       14
<PAGE>

rating bureau or any other organization performing a similar function. Tenant
shall upon demand reimburse Landlord for the full amount of any additional
premium charged for such policy by reason of Tenant's failure to comply with the
provisions of this paragraph. Such reimbursement shall not be Landlord's
exclusive remedy. Tenant shall not in any way obstruct or interfere with the
rights of other tenants or occupants of the Building or the Project or injure,
or use or allow the Premises to be used for any improper, immoral, unlawful, or
objectionable purpose, nor shall Tenant cause, maintain, or permit any nuisance
in, on, or about the Premises. Tenant shall not commit or suffer to be committed
any waste in or upon the Premises.

     Upon the expiration, or early termination of the Term of this Lease or the
permanent assignment of this Lease, or subletting of the Premises, or cessation
or transferring of Tenant's operations at the Premises, or upon any action or
non-action of Landlord including a sale of the Building in which the Premises
are located, Tenant, if its operations are subject to the Environmental Clean-up
Laws hereinafter defined, shall comply, at Tenant's own expense, except as
hereinafter stated, and with diligence, with the Industrial Site Recovery Act,
1993 N.J. Law's Chapter 139, the regulations promulgated thereunder and any
successor legislation and regulations(collectively "Environmental Clean-up
Laws"). Tenant, if its operations are subject to the Environmental Clean-up Laws
shall, at Tenant's own expense, except as hereinafter stated, make prompt
submissions to, provide all information to and comply with all requirements of
the Industrial Site Evaluation Element ("ISEE") or its successor of the New
Jersey Department of Environmental Protection or its successor ("NJDEP") arising
out of the expiration, termination, assignment, subletting or transferring of
Tenant's operation at the Premises or arising out of any action or non-action of
the Landlord including the sale of the Building in which the Premises are
located. If Landlord's actions or non-actions including a sale of the Building
in which the Premises are located necessitate compliance with Environmental
Clean-up Laws, Landlord, at its expense, will make the submissions to NJDEP or
any of its elements in order to obtain a statement of non-applicability or
negative declaration, but Tenant whether or not it is subject to Environmental
Clean-up Laws, will cooperate with Landlord to aid in the making of Landlord's
submission by providing information and signing such documents as are necessary
for Landlord to make its submission. Clean-up expenses or the making up of any
clean-up plan or remedial action work plan, or sampling plan or the taking of
any corrective action to comply with Environmental Clean-up Laws and expenses
therefore, will be borne by the party whose actions or failure to act
necessitated the clean-up.

     Each party shall, within a reasonable time and receipt of same, furnish to
the other party true and complete copies of all documents, submissions,
correspondence and oral or written reports, directives, correspondence and oral
or written communications by ISEE to the recipient party. Each party shall also
promptly furnish to the other party true and complete copies of all sampling and
test results and reports obtained and prepared from samples and tests taken at
and around the Premises that is obtained by the party first obtaining the
results and reports.

     Tenant shall immediately and diligently cause any and all Hazardous
Materials it, its agents, employees, invitees or licensees released in, onto or
under or dispose from the Premises during the Term of the Lease to be removed in
compliance with all applicable

                                       15
<PAGE>

laws, rules, ordinances and regulations and all conditions resulting therefrom
to be remediated in compliance with all applicable laws, rules, ordinances and
regulations and the Premises restored to their condition without said Hazardous
Materials as quickly as possible.

     Tenant shall indemnify, defend and save harmless Landlord from all fines,
suits, procedures, claims and actions of any kind arising out of or in any way
connected with any release or discharge of Hazardous Materials at the Premises
which occur during the term of the Lease as a result of the acts of Tenant, its
invitees or licensees; and from all fines, suits, procedures, claims and actions
of any kind arising out of Tenant's failure to provide all information to NJDEP
or the Landlord as appropriate to make all submissions other than those Landlord
is required to make as provided herein, and take all actions required by the
NJDEP or any of its divisions.

     Landlord hereby agrees to defend, indemnify and hold Tenant harmless from
and against any and all claims, lawsuits,, liabilities, losses, damages and
expenses (including, but not limited to, reasonable attorneys' fees arising by
reason of any of the aforesaid or any action against the Landlord under this
indemnity) arising directly or indirectly from, out of or by reason of (i) any
spills or discharges of toxic or hazardous waste or substances at the Premises
or Project which occur prior to or during the term of this Lease caused by
Landlord, its employees, agents or invitees; or (ii) any pre-existing conditions
including underground tanks, which are the subject of federal, state or local
environmental laws.

     Tenant's obligations and liabilities under this Paragraph shall continue so
long as Landlord remains responsible for any releases or discharges of Hazardous
Materials at the Premises which occur as a result of the acts of Tenant, its
invitees or licensees. Tenant's failure to abide by the terms of this Paragraph
shall be restrainable by injunction.

                            UTILITIES AND SERVICES

                                  PARAGRAPH 9

     (A)  Provided that Tenant is not in default hereunder, Landlord agrees to
furnish or cause to be furnished to the Premises the following utilities and
services, subject to the conditions and standards set forth below:

          (i)   Tenant shall have twenty-four (24) hours per day, seven (7) days
                per week access to the Premises.

          (ii)   Intentionally deleted.

          (iii)  Landlord shall furnish to the Premises at all times, subject to
                 interruptions beyond Landlord's control and subject to
                 subparagraph 3(E), electric current in accordance with the
                 Building Standard office lighting and receptacle. At no time
                 shall Tenant's use of electric current exceed the capacity of
                 the feeders to the Building or the risers

                                       16
<PAGE>

                 or wiring installation. Tenant shall not install or use or
                 permit the installation or use of any mainframe computer
                 equipment in the Premises without the prior written consent of
                 Landlord.

          (iv)   Landlord shall furnish the building with water for (x) drinking
                 and lavatory purposes only at no additional charge; and (y) for
                 laboratory purposes at a reasonable charge.

          (v)    Landlord shall provide janitorial services to the Premises,
                 comparable to such services provided in other first class
                 office buildings in the vicinity, provided that the said other
                 office buildings are used exclusively as offices, and provided
                 further that the Premises are kept in good order by Tenant.
                 Tenant shall pay to Landlord the cost of removal of any of
                 Tenant's refuse and rubbish to the extent that the same exceeds
                 the refuse and rubbish usually attendant upon the use of the
                 Premises as offices.

          (vi)   Landlord shall replace, as necessary, the fluorescent tubes in
                 the standard lighting fixtures installed by Landlord. Tenant
                 agrees to reimburse Landlord upon demand for the cost of such
                 fluorescent tubes and ballast and the labor and overhead for
                 their installation. Initial installation of fixtures will be
                 warranteed for one year for lamps and ballast.

     (B)  Landlord may impose a reasonable charge for any utilities and
services, including without limitation, electric current (except for electricity
paid under subparagraph (E) Paragraph 3 and water), provided by Landlord by
reason of any use of the Premises at any time. Separate meters for such
utilities and services are installed in the Premises, and upon demand, Tenant
shall immediately pay Landlord for all charges with respect to consumption of
such utilities or services so metered or provided (it being understood that the
cost for water for drinking and lavatory purposes is included in the Rent).

          (i)    Intentionally Deleted.

          (ii)   Intentionally Deleted.

          (iii)  Landlord shall not be liable in any way to Tenant for any
                 failure or defect in the supply or character of electric energy
                 furnished to the Premises by reason of any requirement, act or
                 omission of the public utility serving the Building with
                 electricity or for any other reason not attributable to
                 Landlord.

          (iv)   Tenant's use of electric energy in the Premises shall not at
                 any time exceed the capacity of any of the electrical
                 conductors and equipment serving the Premises. In order to
                 insure that such capacity is not exceeded and to avert possible
                 adverse effect upon the Building's

                                       17
<PAGE>

                 electric service, Tenant shall not, without Landlord's prior
                 written consent in each instance (which shall not be
                 unreasonably withheld), connect any additional fixtures,
                 appliances or equipment to the Building's electric distribution
                 system or make any alteration or addition to the electric
                 system of the Premises existing on the Commencement Date.
                 Should Landlord grant such consent, all additional risers or
                 other equipment required therefor shall be provided by Landlord
                 and the cost thereof shall be paid by Tenant upon Landlord's
                 demand.

          (v)    If the public utility rate schedule for the supply of electric
                 current to the Building shall be increased during the term of
                 this Lease, the Additional Rent payable pursuant to Paragraph 3
                 hereof shall be equitably adjusted to reflect the resulting
                 increase in Landlord's cost of furnishing electric service to
                 the Premises. It is the intention hereof that Landlord only
                 recapture the charges payable by Tenant under Paragraph 3 and
                 under no circumstances shall Landlord earn any profit thereof.

     (C)  Tenant agrees to cooperate fully at all times with Landlord and to
abide by all reasonable regulations and requirements which Landlord may
prescribe for the use of the above utilities and services. Any failure to pay
any costs as described above shall constitute a breach of the obligation to pay
Rent under this Lease and shall entitle Landlord to rights herein granted for
such breach.

     (D)  Landlord shall not be liable for, and Tenant shall not be entitled to,
any abatement or reduction of Rent by reason of Landlord's failure to furnish
any of the foregoing services, nor shall any such failure, stoppage or
interruption of any such service be construed either as an eviction of Tenant,
or relieve Tenant from the obligation to perform any covenant or agreement.
However, in the event of any failure, stoppage or interruption thereof, Landlord
shall use reasonable diligence to have service resumed promptly.

     (E)  It is understood and agreed that Landlord has the sole right to choose
the provider or providers of all utilities and services described or referred to
in this Paragraph 9.

     (F)  Notwithstanding anything hereinafter to the contrary, Landlord
reserves the right from time to time to make reasonable modifications to the
above provisions for utilities and services.

                                       18
<PAGE>

                             RULES AND REGULATIONS

                                 PARAGRAPH 10

     Tenant agrees to abide by all rules and regulations of the Buildings and
Project ("Rules and Regulations") imposed by the Landlord as set forth in
Exhibit "D" attached hereto, as the same may be changed from time to time upon
reasonable notice to Tenant. These Rules and Regulations are imposed for the
cleanliness, good appearance, proper maintenance, good order and reasonable use
of the Premises and the Project, as may be necessary for the enjoyment of the
Project by all tenants and their employees and invitees. Landlord shall not be
liable for the failure of any tenant, its agents or employees to conform to the
Rules and Regulations.

                          TAXES AND TENANT'S PROPERTY

                                 PARAGRAPH 11

     (A)  Tenant shall be liable for and shall pay not later than ten (10) days
before delinquency, all taxes, levies and assessments levied against any
personal property or trade fixtures placed by Tenant in or about the Premises.
If any such taxes, levies and assessments on Tenant's personal property or trade
fixtures are levied against Landlord or Landlord's property or if the assessed
value of the Building or the Project is increased by the inclusion therein of a
value placed upon such personal property or trade fixtures of Tenant and if
Landlord pays the taxes, levies and assessments, Tenant shall, upon demand,
repay to Landlord the taxes, levies and assessments so levied against Landlord,
or the proportion of such taxes, levies and assessments resulting from such
increase in the assessment.

     (B)  If Tenant improvements in the Premises, whether installed and/or paid
for by Landlord or Tenant and whether or not affixed to the real property so as
to become as part thereof, are assessed for real property tax purposes at a
valuation higher than the valuation at which Tenant improvements conforming to
"Building Standard" (as referred to in Exhibit "B-2") are assessed, then the
real property taxes and assessments levied against Landlord or the Project by
reason of such excess, assessed valuation shall be deemed to be taxes levied
against personal property of Tenant and shall be governed by the provisions of
subparagraph 11(A). If the records of the Tax Assessor are available and
sufficiently detailed to serve as a basis for determining whether said Tenant
improvements are assessed at a higher valuation than Building Standard, such
records shall be binding on both Landlord and Tenant; otherwise the actual cost
of construction shall be the basis for such determination.

                             SUBSTITUTED PREMISES

                                 PARAGRAPH 12

Intentionally deleted.

                                       19
<PAGE>

                               FIRE OR CASUALTY

                                 PARAGRAPH 13

     In the event that the Project (regardless of whether the Premises or access
thereto is affected) is so damaged or destroyed to the extent of more than one-
third of its replacement cost, or to any substantial extent by a casualty not
covered by Landlord's insurance, or during the last two (2) years of this Lease,
Landlord, upon giving thirty (30) days' notice to Tenant, may elect to terminate
this Lease. If the damage or destruction is other than as provided above, then
Landlord shall commence within ninety (90) days after such damage or destruction
to rebuild, repair or restore the Premises and access thereto to substantially
the same condition as when the same were delivered to Tenant, excluding the
improvements owned by Tenant, and the Lease shall continue in full force and
effect.

     Landlord shall in no event be obligated to make any repairs or replacements
of any items owned by Tenant. If the Lease is not terminated but the Premises
are rendered totally untenantable, Rent shall abate during the period of such
untenantability. Tenant acknowledges (i) that Landlord shall not obtain
insurance of any kind on Tenant's improvements and betterment to the Premises
owned by Tenant or on Tenant's furniture, fixtures, equipment and other personal
property, (ii) that it is Tenant's obligation to obtain such insurance at
Tenant's sole cost and expense, and (iii) that Landlord not be obligated to
repair any damage thereto or replace the same.

                                EMINENT DOMAIN

                                 PARAGRAPH 14

     In case the whole of the Premises, or such part thereof as shall
substantially interfere with Tenant's use and occupancy thereof, shall be taken
by any lawful power or authority by exercise of the power of eminent domain,
Tenant or Landlord may terminate this Lease effective as of the date possession
is required to be surrendered to said authority. In the event of any taking (in
whole or part) of the Project whether or not the Premises or access thereto are
affected thereby, Landlord shall have the right to terminate this Lease. Except
as provided herein, Tenant shall not, because of any taking, assert any claim
against Landlord or the taking authority for any compensation because of such
taking, and Landlord shall be entitled to receive the entire amount of any award
without deduction for any estate or interest of Tenant. In the event the amount
of property or the type of estate taken shall not substantially interfere with
Tenant's use of the Premises, and Landlord does not terminate this Lease,
Landlord shall proceed to restore the Premises (to the extent permitted by the
taking) to substantially their condition prior to such partial taking, and a
proportionate allowance shall be made to Tenant for Rent corresponding to the
time during which, and to the part of the Premises of which, Tenant shall be so
deprived on account of such taking and restoration. Provided same shall not
diminish Landlord's award in any way, nothing contained in this Paragraph 14
shall prevent Tenant from seeking any award against the taking authority for the
taking of personal property and fixtures owned by Tenant or for relocation
expenses recoverable from the taking authority. In no event shall Landlord be

                                       20
<PAGE>

required to expend more for restoration than received from the taking authority
for such taking. For the purposes of this paragraph, "taking" shall also include
any conveyance in lieu of condemnation.

                           ASSIGNMENT AND SUBLETTING

                                 PARAGRAPH 15

     (A)  Tenant shall not voluntarily or involuntarily assign, sublet,
mortgage, or otherwise encumber all or any portion of its interest in this Lease
or in the Premises without obtaining the prior written consent of Landlord
(which consent shall not be unreasonably withheld) and any such attempted
subletting, mortgage or other encumbrance without such consent shall be null and
void and of no effect. Without limiting the instances in which the Landlord will
refuse to give its consent, Landlord will withhold its consent where the Rent
per month of the proposed sublease or assignment is (i) less than ninety (90%)
of the Rent per month in effect for the remainder of the term of this Lease, or
(ii) where the proposed sublessee is either another tenant of Landlord or a
bonafide prospective tenant of Landlord.

     (B)  No assignment, subletting, mortgage or other encumbrance of Tenant's
interest in this Lease shall relieve Tenant of its obligation to pay the Rent
and to perform all of the other obligations to be performed by Tenant hereunder.
The acceptance of Rent by Landlord from any other person shall not be deemed to
be a waiver by Landlord of any provision of this Lease or be a consent to any
subletting, assignment, mortgage or other encumbrance. Consent to one sublease,
assignment, mortgage or other encumbrance shall not be deemed to constitute
consent to any subsequent attempted subletting, assignment, mortgage or other
encumbrance.

     (C)  If Tenant desires at any time to assign this Lease or to sublet the
Premises or any portion thereof, Tenant shall first notify Landlord of Tenant's
desire to do so and shall submit in writing to Landlord no less than sixty (60)
days prior to such assignment or subletting (i) the name of the proposed
subtenant or assignee; (ii) the premises; (iii) the term and provisions of the
proposed sublease or assignment and a copy of the proposed sublease or
assignment; and (iv) such financial information as Landlord may reasonably
request concerning the proposed subtenant or assignee.

     (D)  At any time within thirty (30) days after Landlord's receipt of the
information specified in subparagraph (C) above, Landlord may by written notice
to Tenant, elect (i) to take from Tenant a sublease of the Premises or the
portion thereof proposed to be subleased by Tenant, or to take an assignment of
Tenant's leasehold estate hereunder, or such part thereof as shall be specified
in said notice, upon the same terms as those offered to the proposed subtenant
or assignee, as the case may be; (ii) to give Tenant written consent to the
proposed assignment or sublease, provided that the Rent payable monthly by the
Tenant to the Landlord under the terms of this Lease shall be increased by a sum
equal to one-half (1/2) of all rental and other considerations received by
Tenant from its subtenant or assignee in excess of the Rent payable by Tenant
under the terms of this Lease (less the cost of brokerage commissions and/or
reasonable legal fees); or (iii) to terminate

                                       21
<PAGE>

this Lease as to the portion (including all) of the Premises proposed to be
subleased or assigned with a proportionate abatement in the Rent payable
hereunder. If Landlord does not exercise any option set forth in this
subparagraph (D) within said thirty (30) day period, Landlord shall be deemed to
have refused to consent to the proposed assignment or sublease and this Lease
shall remain in full force and effect.

     (E)  Except as provided in (i) immediately below, if Tenant is a
corporation, an unincorporated association or partnership, the transfer,
assignment or hypothecation of any stock or interest in such corporation,
association or partnership, in the aggregate in excess of forty-nine (49%)
percent, shall be deemed an assignment within the meaning and provisions of this
Paragraph.

          (i)    Without Landlord being able to terminate pursuant to Paragraph
                 15 (D), Tenant, if it is not then in material default of this
                 Lease may, without Landlord's consent but with notice to
                 Landlord with such information as Landlord may reasonably
                 request, sublet all or part of the Premises or assign this
                 Lease to any parent, affiliate or wholly-owned subsidiary of
                 Tenant; or assign this Lease to a corporation, or a subsidiary
                 of a corporation which succeeds to all or substantially all of
                 the assets and business of Tenant or into which Tenant is
                 merged; provided, however, that Tenant shall at all times be
                 and remain primarily and jointly liable under this Lease
                 despite any such subletting or assignment and provided further
                 that any surviving entity in a merger or any assignee or
                 subtenant has a net worth at least as much as Tenant had on the
                 Commencement Date and such successor, if an assignee or
                 survivor in a merger becomes liable on this Lease.

     (F)  Tenant shall reimburse Landlord for Landlord's reasonable costs and
attorneys' fees incurred in conjunction with the processing and documentation of
any such requested assignment, subletting, transfer, change in ownership or
hypothecation of this Lease or Tenant's interest in and to the Premises.

                         LANDLORD'S ACCESS TO PREMISES

                                 PARAGRAPH 16

     Landlord reserves and shall at any and all reasonable times have the right
to enter the Premises to inspect the same, to supply janitorial service and any
other service to be provided by Landlord to Tenant hereunder, to show said
Premises to prospective purchasers or tenants, to alter or repair the Premises
or any portion of the Building or Project, all without being deemed guilty of an
eviction of Tenant and without abatement of Rent, and may for that purpose erect
scaffolding and other necessary structures where reasonable required by the
character of the work to be performed, provided that the business of Tenant
shall be interfered with as little as is reasonably practicable. Tenant hereby
waives any claim for damages or any injury or inconvenience to or interference
with Tenant's business, any loss of occupancy or quiet enjoyment of the
Premises, and any other loss occasioned thereby. For each of the aforesaid
purposes, Landlord shall at all times have and retain a

                                       22
<PAGE>

key with which to unlock all of the doors in, upon and about the Premises,
excluding Tenant's vaults and safes, and Landlord shall have the right to use
any and all means which Landlord may deem proper to open said doors in an
emergency in order to obtain entry to the Premises, and any entry to the
Premises obtained by Landlord by any of said means shall not under any
circumstances be construed or deemed to be a forcible or unlawful entry into, or
a detainer of the Premises, or any eviction of Tenant from the Premises or any
portion thereof. No provision of this Lease shall be construed as obligating
Landlord to perform any repairs, alterations or decoration except as otherwise
expressly agreed to be performed by Landlord.

               SUBORDINATION, ATTORNMENT, ESTOPPEL CERTIFICATES

                                 PARAGRAPH 17

     (A)  This Lease is junior, subject, and subordinate to all ground leases,
mortgages, deeds of trust, and other security instruments of any kind now
covering the Project or any portion thereof. Landlord reserves the right to
place liens or encumbrances on the Project or any part thereof or interest
therein superior in lien and effect to this Lease. This Lease, at the option of
Landlord, shall be subject and subordinate to any and all such liens or
encumbrances now or hereafter imposed by Landlord without the necessity of the
execution and delivery of any further instruments on the part of Tenant to
effectuate such subordination. Notwithstanding the foregoing, Tenant covenants
and agrees to execute and deliver upon request such further instruments
evidencing such subordination of this Lease as may be requested by Landlord.
Landlord will request a Subordination and Non-Disturbance Agreement from its
current mortgagee (and any future mortgagee if requested) of the Project.

     (B)  Tenant shall at any time and from time to time upon not less than ten
(10) days' prior notice by Landlord, execute, acknowledge and deliver to
Landlord a statement in writing and in form and substance. satisfactory to
Landlord certifying that this Lease is unmodified and in full force and effect
(or if there have been modifications, that the same is in full force and effect
as modified and stating the modifications), and the dates to which the Basic
Annual Rent, Additional Rent and other charges have been paid in advance, if
any, and stating whether or not to the best knowledge of Tenant, Landlord is in
default in the performance of any covenant, agreement or condition contained in
this Lease and, if so, specifying each such default of which Tenant may have
knowledge. Any such statement delivered pursuant to this Paragraph may be relied
upon by any prospective purchaser of the fee of the Building or the Project or
any mortgagee, ground lessor or other encumbrancer thereof or any assignee of
any such person.

     (C)  Should any mortgage on the Property of which the Premises are a part
be foreclosed, the Purchaser upon foreclosure of the lien of the mortgage shall
have the right following foreclosure to preserve this Lease and the rights of
the Tenant or any other person or entity having an interest in the Premises, and
the Tenant shall attorn to such Purchaser at foreclosure and pay and perform its
obligations under this Lease for the benefit of such Purchaser.

                                       23
<PAGE>

                               SALE BY LANDLORD

                                 PARAGRAPH 18

     In the event of a sale or conveyance by Landlord of the Project or any part
thereof, the same shall operate to release Landlord from any and all liability
under this Lease after the date of such conveyance of title. If any security
deposit has been made by Tenant, Landlord shall transfer such security deposit
to the purchaser, and thereupon Landlord shall be discharged from any further
liability in reference thereto.

                   INDEMNIFICATION OF LANDLORD AND INSURANCE

                                 PARAGRAPH 19

     (A)  Except for negligent acts or omissions of Landlord, its agents,
servants, employees or invitees, Tenant shall indemnify, hold Landlord harmless
from and defend Landlord against any and all claims, loss, costs, damage,
expense or liability, including without limitation reasonable attorneys' fees,
for any injury or damages to any person or property whatsoever when such injury
has been caused in part or in whole by any act, neglect, fault, or Omission of
Tenant, its agents, servants, employees or invitees. This indemnity shall not
require any payment by Landlord as condition precedent to recovery. In addition,
if any person not a party to this Lease shall institute any other type of action
against Tenant in which Landlord shall be made a party defendant, Tenant shall
indemnify, hold Landlord harmless from and defend Landlord from all liabilities
and costs by reason thereof.

     (B)  Tenant hereby agrees to maintain in full force and effect at all times
during the term of this Lease, at its own expense, for the protection of Tenant
and Landlord as their interests may appear, policies of insurance issued by a
responsible carrier or carriers acceptable to Landlord licensed in New Jersey
and also having a policyholder's rating of not less than A- in the most current
edition of Best's Insurance Reports, which afford the following coverage:

          (i)    Worker's Compensation            --  Statutory
                 Employer's Liability             --  Not less than $250,000

          (ii)   Comprehensive General            --  Not less than $3,000,000
                 Liability Insurance              Combined Single Limit for both
                 including Blanket                bodily injury and property
                 Contractual Liability            damage
                 Broad Form Property Damage,
                 Personal Injury, Completed
                 Operations, Products Liability,
                 Fire Damage

          Landlord and its managing agent shall be named as an additional
          insured on all policies listed under (ii) above, and (iv) below.

                                       24
<PAGE>

          (iii)  All Risk Property Coverage in an amount sufficient to cover the
                 full cost of replacement of all improvements and betterment to
                 the Premises owned by Tenant and all of Tenant's fixtures and
                 other personal property.

          (iv)   Business Interruption Insurance (which includes Rent Insurance)
                 in an amount equal to the Basic Annual Rent and Additional Rent
                 for a period of at least twelve (12) months commencing with the
                 date of loss.

     (C)  Tenant shall deliver to Landlord at least thirty (30) days prior to
the time such insurance is first required to be carried by Tenant and thereafter
at least thirty (30) days prior to expiration of each such policy, certificates
of insurance evidencing the above coverage with limits not less than those
specified above. Such policy or certificate, with the exception of Worker's
Compensation, shall expressly provide that the interest of Landlord therein
shall not be affected by any breach by Tenant of any provision of any such
policy. Further, all certificates shall expressly provide that no less than
thirty (30) days prior written notice shall be given Landlord in the event of
material alterations to or cancellation of the coverage evidenced by such
certificates.

     (D)  Upon demand, Tenant shall provide Landlord, at Tenant's expense, with
such increased amount of existing insurance, and such other insurance in such
limits as Landlord may reasonably require and such other hazard insurance as the
nature and condition of the Premises may require in the sole judgement of
Landlord, to afford Landlord adequate protection for said risks. Such increased
insurance shall be comparable with that which is required by other landlords of
comparable buildings in the area.

     (E)  If on account of the failure of Tenant to comply with the provisions
of this Paragraph 19, Landlord is adjudged a coinsurer by its insurance carrier,
then any loss or damage Landlord shall sustain by reason thereof shall be borne
by Tenant and shall be immediately paid by Tenant upon receipt of a bill
therefore and evidence of such loss.

     (F)  Landlord makes no representation that the limits of liability
specified to be carried by Tenant under the terms of this Lease are adequate to
protect Tenant against Tenant's undertaking under this Paragraph 19. In the
event Tenant believes that any such insurance coverage called for under this
Lease is insufficient, Tenant shall provide, at its own expense, such additional
insurance as it deems adequate.

     (G)  Each policy evidencing the insurance to be carried by Tenant under
this Lease shall contain a clause that such policy and the coverage endorsed
thereby shall be primary with respect to any policies carried by Landlord, and
that any coverage carried by Landlord shall be excess insurance.

     (H)  Any insurance required of Tenant under this Lease may be furnished by
Tenant under a blanket policy carried by it. Such blanket policy shall contain
an endorsement that names Landlord as an additional insured, references the
Premises, and guarantees a minimum limit available for the Premises equal to the
insurance amounts

                                       25
<PAGE>

required in this Lease.

     (I)  In the event Tenant fails to procure, maintain, and/or pay for the
insurance required by this Lease, at the times and for the durations specified
in this Lease, Landlord shall have the right, but not the obligation, at any
time and from time to time, and without notice, to procure such insurance and/or
pay the premiums for such insurance, in which event Tenant shall repay Landlord,
immediately upon demand by Landlord, as Additional Rent, all sums so paid by
Landlord together with interest thereon and any costs or expenses incurred by
Landlord in connection therewith, without prejudice to any other rights and
remedies of the Landlord under this Lease.

                             WAIVER OF SUBROGATION

                                 PARAGRAPH 20

     Tenant and Landlord each agree that the respective insurance carried by it
against loss or damage by fire or other casualty shall contain a clause whereby
the insurer waives its right of subrogation against the other party.

     Pursuant to the foregoing, Landlord and Tenant hereby waive all claims for
recovery from the other party for any loss or damage to any of its property
insured under valid and collectible insurance policies to the extent of any
recovery collectible under such insurance. The foregoing waiver shall be in
force only if both Tenant's and Landlord's insurance policies contain a clause
providing that such waiver shall not invalidate the insurance.

                                   NO WAIVER

                                 PARAGRAPH 21

     No waiver by Landlord of any provision of this Lease or of any breach by
Tenant hereunder shall be deemed to be a waiver of any other provision hereof,
or for any subsequent breach by Tenant of the same or any other provisions.
Landlord's consent to or approval of any act by Tenant requiring Landlord's
consent or approval shall not be deemed to render unnecessary the obtaining of
Landlord's consent to or approval of any subsequent act of Tenant. Failure of
Landlord to insist upon strict performance of any provision of this Lease shall
not be deemed to be a waiver of such provision. No act or omission by Landlord
or Landlord's agents during the term of this Lease shall be deemed an acceptance
of a surrender of the Premises, unless confirmed by Landlord in writing. The
delivery of the keys to an employee or agent of Landlord shall not operate as a
termination of the Lease or a surrender of the Premises. The acceptance of any
Rent by Landlord following a breach of this Lease by Tenant shall not constitute
a waiver of any of Landlord's rights unless such waiver is expressly stated in
writing and signed by Landlord.

                                       26
<PAGE>

                                    DEFAULT

                                 PARAGRAPH 22

     (A)  The occurrence of any of the following shall constitute a material
default and breach of this Lease by Tenant:

          (i)    Any failure by Tenant to pay the Rent or to make any other
                 payment required to be made by Tenant hereunder within five (5)
                 days of date due;

          (ii)   The abandonment or vacation of the Premises by Tenant;

          (iii)  Any failure by Tenant to observe and perform any of its
                 obligations under this Lease, not referred to in (i) above,
                 where such failure continues for fifteen (15) days after
                 Landlord has given Tenant written notice, provided, however,
                 that if the nature of Tenant's default is such that more than
                 fifteen (15) days are reasonably required for its cure, then
                 Tenant shall not be deemed to be in default if Tenant has been
                 pursuing such cure with reasonable diligence, within the
                 fifteen (15) day period and thereafter diligently completes the
                 cure; where such failure continues for fifteen (15) days after
                 Landlord has given Tenant written notice or such other notice
                 as may be required by law;

          (iv)   Tenant makes, or has made, or furnishes, or has furnished, any
                 warranty, representation or statement to Landlord in connection
                 with this Lease, or any other agreement to which Tenant and
                 Landlord are parties, which is or was false or misleading in
                 any material respect when made or furnished;

          (v)    Any substantial portion of the assets of Tenant is transferred
                 unless such transfer is incurred in the ordinary course of
                 Tenant's business in good faith for fair equivalent
                 consideration, and with Landlord's consent, and except for a
                 transfer of assets subject to Paragraph 15 E (i);

          (vi)   Tenant becomes insolvent as defined in the Federal Bankruptcy
                 Code, admits in writing its insolvency or its present or
                 prospective inability to pay its debts as they become due, is
                 unable to or does not pay all or any material portion (in
                 number or dollar amount) of its debts as they become due,
                 permits or suffers a judgement to exist against it which
                 affects Tenant's ability to conduct its business in the
                 ordinary course (unless enforcement thereof is stayed pending
                 appeal), makes or proposes an assignment for .the benefit of
                 creditors or any class thereof for purposes of effecting a
                 moratorium upon or extension or composition, or commences or
                 proposes to commence any bankruptcy,

                                       27
<PAGE>

                 reorganization or insolvency proceeding, or other proceedings
                 under any federal, state or other law for the relief of
                 debtors;

          (vii)  Tenant fails to obtain the dismissal, within thirty (30) days
                 after the commencement thereof, of any bankruptcy,
                 reorganization or insolvency proceeding, or other proceeding
                 under any law for the relief of debtors, instituted against it
                 by one or more third parties, or fails actively to oppose any
                 such proceedings, or, in any such proceeding, defaults or files
                 an answer admitting the material allegations upon which the
                 proceeding was based or alleges its willingness to have an
                 order for relief entered or its desire to seek liquidation,
                 reorganization or adjustment of any of its debts;

          (viii) Any receiver, trustee, or custodian is appointed to take
                 possession of all or any substantial portion of the assets of
                 Tenant, or any committee of Tenant, or any committee of
                 Tenant's creditors, or any class thereof is formed for the
                 purpose of monitoring or investigating the financial affairs of
                 Tenant or enforcing such creditors' rights.

     (B)  In the event of any such material default and breach of this Lease by
Tenant, then in addition to any other remedies available to Landlord at law or
in equity, Landlord shall have the option to immediately terminate this Lease
and all rights of Tenant hereunder by giving written notice of such intention to
terminate. In the event that Landlord shall elect to so terminate the Lease,
then Landlord may recover from Tenant:

          (i)    any unpaid Rent which shall have accrued at the time of such
                 termination; plus

          (ii)   the entire amount of unpaid Rent for the balance of the term
                 which amount shall, at Landlord's option, be immediately due
                 and payable; plus

          (iii)  any other amount necessary to compensate Landlord for
                 Landlord's loss or damage caused directly or indirectly by
                 Tenant's failure to perform its obligations under this Lease
                 including, but not limited to, reasonable attorneys' fees and
                 costs; plus

          (iv)   at Landlord's election, such other amounts in addition to, or
                 in lieu of the foregoing, as may be permitted from time to time
                 by applicable law.

     (C)  In the event of any such material default and breach of this Lease by
Tenant, Landlord shall also have the right, with or without terminating this
Lease, to re-enter and to take possession of the Premises and to remove all
persons and property from the Premises. Landlord is hereby granted a lien, in
addition to any statutory lien or right to distrain that may exist, on all
personal property of Tenant in or upon the Premises to assure payment of the
Rent and performance of the covenants and conditions of this Lease.

                                       28
<PAGE>

Landlord shall have the right, as agent of Tenant, to take possession of all
personal property of Tenant found in or about the Premises including without
limitation furniture and fixtures of Tenant and, to sell the same at public or
private sale and to apply the proceeds thereof to the payment of any monies due
or becoming under this Lease, or to remove all such effects and store same in a
public warehouse or elsewhere at the cost of and for the account of Tenant, or
any other owner or occupant, Tenant hereby waiving the benefit of all laws
exempting property from executing, levy and sale of distress or judgement.

     (D)  In the event of the vacation or abandonment of the Premises by Tenant
or in the event that Landlord shall elect to re-enter as provided above or shall
take possession of the Premises pursuant to legal proceeding or pursuant to any
notice provided by law, then if Landlord does not elect to terminate this Lease
as provided in this Paragraph 22, Landlord may from time to time, without
terminating this Lease, either recover all Rent as it becomes due or relet the
Premises or any part thereof for such term or terms and at such rental or
rentals and upon such other terms and conditions as Landlord in his sole
discretion may deem advisable with the right to make alterations and repairs to
the Premises.

     (E)  In the event that Landlord shall elect to so relet, then rentals
received by Landlord from such reletting shall be applied: first, to the payment
of any indebtedness other than Rent due hereunder from Tenant to Landlord;
second, to the payment of any cost of such reletting, including but not limited
to broker's commissions and reasonable attorneys' fees; third, to the payment of
the cost of any alterations and repairs to the premises; fourth, to the payment
of any Rent due and unpaid hereunder; and the residue, if any, shall be held by
Landlord and applied in payment of future Rent as the same may become due and
payable hereunder. Should any such reletting result in the payment of rentals
less than the Rent payable by Tenant hereunder, then Tenant shall pay such
deficiency to Landlord immediately upon demand therefor by Landlord. Tenant
shall also pay Landlord as soon as ascertained, any costs and expenses incurred
by Landlord in such reletting or in making such alterations and repairs not
covered by the rentals received from such reletting.

     (F)  No re-entry or taking possession of the Premises by Landlord pursuant
to this Paragraph 22 shall be construed as an election to terminate this Lease
unless a written notice of such intention be given to Tenant. Notwithstanding
any reletting without termination by Landlord because of any default by Tenant,
Landlord may at any time after such reletting, elect to terminate this Lease for
any such default.

                  RIGHT OF LANDLORD TO CURE TENANT'S DEFAULT

                                 PARAGRAPH 23

     If Tenant defaults in the making of any payment or in the doing of any act
herein required to be made or done by Tenant, then Landlord may but shall not be
required to make such payment or do such act and charge to Tenant the amount of
41 costs in connection therewith including but not limited to reasonable legal
fees and expenses

                                       29
<PAGE>

incurred by Landlord, with interest thereon as provided in Paragraph 36 from the
date paid by Landlord to the date of payment thereof by Tenant. Such payment and
interest shall constitute Additional Rent hereunder due and payable upon demand
but the making of such payment or the taking of such action by Landlord shall
not operate to cure such default or to stop Landlord from the pursuit of any
other remedy to which Landlord would otherwise be entitled.

                                    NOTICES

                                 PARAGRAPH 24

     All notices which Landlord or Tenant may be required or may desire to serve
on the other may be served, as an alternative to personal service, by mailing
the same by registered or certified mail, return receipt requested, postage
prepaid, addressed as set forth in Item 14 of the Basic Lease Provisions, or
addressed to such other address or addresses as either Landlord or Tenant may
from time to time designate to the other by written notice.

                           INSOLVENCY OR BANKRUPTCY

                                 PARAGRAPH 25

     In no event shall this Lease be assigned or assignable by operation of law
and in no event shall this Lease be an asset of Tenant in any receivership,
bankruptcy, insolvency, or reorganization proceeding.

                            SURRENDER AND HOLDOVER

                                 PARAGRAPH 26

     (A) On the expiration or the sooner termination hereof, Tenant shall
peaceably surrender the Premises broom clean, in good order, condition and
repair. On or before the last day of the term or the sooner termination hereof,
Tenant shall at its expense remove its trade fixtures, signs and other personal
property from the Premises. Any property not removed shall be deemed abandoned
and may either retained by Landlord as its property, or disposed of, without
accountability and at Tenant's expense, in such manner as Landlord may
determine. If the Premises are not surrendered at the end of the term or the
sooner termination, Tenant shall indemnify Landlord against loss or liability
resulting from delay by Tenant in so surrendering the Premises, including,
without limitation, claims made by any succeeding tenants found on such delay.
Tenant shall promptly surrender all keys for the Premises and Building restrooms
to Landlord at the place then fixed for payments of Rent. Tenant's covenants
hereunder shall survive the expiration or termination of this Lease.

     (B) If Tenant holds over after the expiration or sooner termination hereof
without the express written consent of Landlord, Tenant shall become a Tenant at
sufferance only

                                       30
<PAGE>

at two times the greater of (i) the Rent due hereunder or (ii) the then
prevailing market rate rent, as determined by Landlord in its sole and absolute
discretion, plus all items of Additional Rent provided herein, and either (i) or
(ii) shall be prorated on a daily basis according to the number of days
contained in the month that such expiration or earlier termination takes place,
and otherwise upon the terms, covenants and conditions herein specified, so far
as applicable. Acceptance by Landlord of Rent after such expiration or earlier
termination shall not constitute a consent to a holdover hereunder or result in
a renewal. The foregoing provisions of this paragraph are in addition to and do
not affect Landlord's rights of re-entry or any other rights of Landlord
hereunder or as otherwise provided by law.

                             CONDITION OF PREMISES

                                 PARAGRAPH 27

     Landlord's sole responsibility for preparation of the Premises will be as
set forth in the Work Letter attached hereto as Exhibit "B-I" and if there is no
Work Letter, Landlord's sole responsibility will consist of building of a
demising wall and an entry door for Tenant. Landlord's responsibility for the
preparation of the Premises as described above is hereinafter referred to as
Landlord's Work. Except for Landlord's Work, Tenant acknowledges that neither
Landlord nor any agent of Landlord has made any representation or warranty with
respect to the Premises, the Building or the Project for the conduct of Tenant's
business. The taking of possession of the Premises by Tenant shall conclusively
establish that the Building and the Premises were at such time in good order and
repair.

                               QUIET POSSESSION

                                 PARAGRAPH 28

     Upon Tenant's paying the rent reserved hereunder and observing and
performing all of the covenants, conditions and provisions on Tenant's part to
be performed hereunder, Tenant shall have quiet possession of the Premises for
the entire term hereof, subject to all of the provisions of this Lease. This
covenant shall be binding upon any Landlord hereunder only during its respective
ownership of the Premises.

                      LIMITATION OF LANDLORD'S LIABILITY

                                 PARAGRAPH 29

     (A) Landlord and its employees and agents shall not be liable for any
damage to

Tenant's property entrusted to employees of Landlord or its agents, nor for any
loss or interruption of Tenant's possession, nor for loss of or damage to any
property by theft or otherwise, nor for any injury or damage to persons or
property resulting from fire, explosion,

                                       31
<PAGE>

falling plaster, steam, gas, electricity, water or rain which may leak from any
part of the Building or from the pipes, appliances or plumbing works therein or
from the roof, street, or sub-surface or from any other place or resulting from
dampness or any other cause whatsoever in the Building or the Project. Landlord
and its employees and agents shall not be liable for any property loss resulting
from any latent defect in the Premises or in the Building. Notwithstanding the
foregoing provisions of this Paragraph 29(A) to the contrary, Landlord and its
employees and agents shall indemnify, hold harmless and indemnify Tenant against
any claims, loss, costs, damage expense, liability, including without limitation
reasonable attorney's fees, for any injury or damages to any person or property
whatsoever to the extent such injury has been caused by the gross negligence or
willful misconduct of Landlord, its agents, servants, employees or invitees or
when such injury has been caused in part or in whole by any defects relating to
Landlord's obligations with respect to the Landlord's Work which could not have
been discovered by a careful visual inspection or normal use within the three
(3) month period following the issuance of the certificate of occupancy for the
Premises.

     (B) Tenant shall look solely to Landlord's estate and property in the
Project (or the proceeds thereof) for the satisfaction of Tenant's remedies for
the collection of a Judgement (or other judicial process) requiring the payment
of money by Landlord in the event of any default by Landlord hereunder, and no
other property or assets of Landlord or Landlord's partners or members shall be
subject to levy, execution or other enforcement procedure for the satisfaction
of Tenant's remedies under or with respect to either this Lease, the
relationship of Landlord and Tenant hereunder, or Tenant's use and occupancy of
the Premises.

                                 GOVERNING LAW

                                 PARAGRAPH 30

     This Lease shall be governed by and construed pursuant to the laws of the
State of New Jersey.

                               COMMON FACILITIES

                                 PARAGRAPH 31

     Tenant shall have the non-exclusive right in common with others, to the use
of common entrances, lobbies, elevators, ramps, drives, stairs and similar
access and serviceways and the other common facilities (except for parking
spaces other than those provided for in Paragraph 39) in and adjacent to the
Building or Project, as may be provided by Landlord from time to time for
general use, subject to such rules and regulations as may be adopted by the
Landlord including, but not limited to, the right to close from time to time all
or a portion of said common facilities to such extent as may be legally
sufficient, in Landlord's sole opinion, to prevent a dedication thereof or the
accrual of rights to any person or to the public therein.

                                       32
<PAGE>

                            SUCCESSORS AND ASSIGNS

                                 PARAGRAPH 32

     Except as otherwise provided in this Lease, all of the covenants,
conditions and provisions of this Lease shall be binding upon and shall inure to
the benefit of the parties hereto and their respective heirs, personal
representatives, successors and assigns. However, the obligations of Landlord
under this Lease shall not be binding upon Landlord herein named with respect to
any period subsequent to the transfer of its interest in the Project as owner or
lessee thereof, and in the event of such transfer said obligations shall
thereafter be binding upon each transferee of the interest of Landlord herein
named as such owner or lessee of the Project, but only with respect to the
period commencing with its respective transfer in and ending with a subsequent
transfer out, and such transferee, by accepting such interest, shall be deemed
to have assumed such obligations except only as may be expressly otherwise
provided in this Lease. A lease of Landlord's entire interest in the Project as
owner or lessee thereof shall be deemed a transfer within the meaning of this
Paragraph 32.

                                    BROKERS

                                 PARAGRAPH 33

     Tenant represents and agrees that it has not directly or indirectly dealt
with any real estate broker(s) other than the firm(s) specified in Item 12 of
Basic Lease Provisions in connection with this transaction. Further, Tenant
covenants and agrees that with respect to any renewal or extension or expansion
of this Lease, or with respect to any transaction by Tenant or its affiliates,
successors or assigns with Landlord or 400 College Road Associates, Limited
Partnership with respect to the leasing of space by Tenant either by original
lease, renewal or expansion space within any buildings owned by Landlord or 400
College Road Associates, Limited Partnership within College Park at Princeton
Forrestal Center in Plainsboro, New Jersey, that Tenant will pay all brokerage
commissions or finders fees, commissions, fees or other remuneration claimed by
any real estate broker or finder other than the firm(s) specified in Item 12 of
the Basic Lease Provisions. Tenant agrees to defend, indemnify and hold Landlord
harmless from and against any claims for brokerage commissions or finder's fee
arising out of or based upon any actions of Tenant with respect to any other
broker or brokers other than the firm(s) specified in Item 12 of the Basic
Lease Provisions with respect to the leasing of space by Tenant, either by
original lease, renewal, or expansion space for any space including, but not
limited to the Premises, leased by Tenant or its affiliates, successors or
assigns from Landlord or 400 College Road Associates, Limited Partnership within
the buildings owned by either of them at College Park at Princeton Forrestal
Center in Plainsboro, New Jersey. The terms of this Paragraph will survive
termination of this Lease. With respect to this transaction, Landlord shall pay
the firm specified in Item 12 of the Basic Lease Provisions via a separate
agreement.

                                       33
<PAGE>

                                     NAME

                                 PARAGRAPH 34

     Tenant shall not, without the written consent of Landlord, use the name of
the Building or the Project for any purpose other than as the address of the
business to be conducted by Tenant in the Premises, and in no event shall Tenant
acquire any rights in or to such names.

                             EXAMINATION OF LEASE

                                 PARAGRAPH 35

     Submission of this instrument for examination or signature by Tenant does
not constitute a reservation of or option for lease, and it is not effective as
a Lease or otherwise until execution by and delivery to both Landlord and
Tenant.

                               ADDITIONAL CHARGES

                                  PARAGRAPH 36

     Any amount due from Tenant to Landlord which is not paid when due, in
addition to other remedies available to Landlord, shall at Landlord's option
bear interest which shall be at the lesser of (i) eighteen (18%) percent per
annum or (ii) the maximum lawful rate per annum, from the date such payment is
due until paid, but the payment of such interest shall not excuse the cure of
default. In addition to the foregoing, Landlord may also impose a late charge of
four (4%) percent of the amount past due, and a charge for reasonable legal fees
and costs.

                               MARGINAL HEADINGS

                                 PARAGRAPH 37

     The marginal headings and titles to the Paragraphs of this Lease are not a
part of this Lease and shall have no effect upon the construction or
interpretation of any part hereof.

                                       34
<PAGE>

                         PRIOR AGREEMENTS; SEVERABILITY

                                  PARAGRAPH 38

     This Lease contains all of the agreements of the parties hereto with
respect to any matter covered or mentioned in this Lease, and no prior
agreement, understanding or representation pertaining to any such matter shall
be effective for any purpose. No provision of this Lease may be amended or added
to except by an agreement in writing signed by the parties hereto or their
respective successors in interest. If any term or provision of this Lease, the
deletion of which would not adversely affect the receipt of any material benefit
by either party hereunder, shall be held invalid or unenforceable to any extent,
the remainder of this Lease shall not be affected thereby and each term and
provision of this Lease shall be valid and enforceable to the fullest extent
permitted by law.

                                    PARKING

                                  PARAGRAPH 39

     Tenant shall have the right to the non-exclusive use of the number of
parking spaces shown in Item 11 of Basic Lease Provisions. Tenant covenants and
agrees to comply with all reasonable rules and regulations which Landlord may
hereafter from time to time make to assure use of parking spaces by permitted
users. Landlord's remedies under such rules and regulations may include, but
shall not be limited to, the right to tow away at owner's expense any vehicles
not parked in compliance with these rules and regulations. Landlord shall not be
responsible to Tenant for the noncompliance or breach by any other tenant of
said rules and regulations.

                                   AUTHORITY

                                  PARAGRAPH 40

     Tenant represents that Tenant is authorized to do business in the State of
New Jersey. Upon Landlord's request, Tenant's signatories hereto will furnish
satisfactory evidence of Tenant's authorization and their authority to execute
this Lease on behalf of Tenant.

                         NO LIGHT, AIR OR VIEW EASEMENT

                                  PARAGRAPH 41

     Any diminution or shutting off of light, air or view of any structure which
may be erected on lands adjacent to the Building shall in no way effect this
Lease or impose any liability on Landlord.

                                       35
<PAGE>

                                 FORCE MAJEURE

                                  PARAGRAPH 42

     Except as otherwise expressly provided herein, this Lease and the
obligations of Tenant to pay Rent hereunder and perform all of the other
covenants, agreements, terms, provisions and conditions hereunder on the part of
Tenant to be performed shall in no way be affected, impaired or excused because
Landlord is unable to fulfill any of its obligations under this Lease, if
Landlord is prevented or delayed from so doing by reason of any cause beyond
Landlord's reasonable control, including, but not limited to, Acts of God,
strikes, labor troubles, shortage of material, governmental preemption in
connection with a national emergency or by reason of any rule, order or
regulations of any governmental agency or by reason of war, hostilities or
similar emergency; provided that Landlord shall in each instance exercise
reasonable diligence to effect performance as soon as possible. It is agreed
that Landlord shall not be required to incur any overtime or additional expenses
in Landlord's reasonable diligence to effect the performance of any of
Landlord's obligations hereunder.

                                   ATTORNMENT

                                  PARAGRAPH 43

     If for any reason the leasehold estate of Landlord as Tenant under any
underlying lease is terminated by summary proceedings or otherwise, Tenant will
attorn to the Landlord under such underlying Lease and will recognize such
Landlord as Tenant's Landlord under this (sub)lease. Tenant agrees to execute
and deliver, at any time, and from time, to time, upon the request of Landlord
or of the Landlord under any such underlying lease, any instrument which may be
necessary or appropriate to evidence such attornment and Tenant hereby appoints
Landlord the Landlord under such underlying lease the attorney-in-fact,
irrevocable, of Tenant to execute and deliver any such instrument for and on
behalf of Tenant. Tenant further waives the provisions of any statute or rule of
law now or election to terminate this (sub)lease or to surrender possession of
the Premises in the event such underlying lease terminates or any such
proceeding is brought by Landlord under such underlying lease, and agrees that
his (sub)lease shall not be affected in any way whatsoever by any such
proceeding or termination.

                          COMMON AREA MAINTENANCE COST

                                  PARAGRAPH 44

     Base Project Operating Expenses as defined in Paragraph 3 shall also
include Landlord's costs and expenses incurred as Landlord's share of common
area maintenance all as set forth in Article 29 of the underlying Land Lease
between the Trustees of Princeton University as landlord and Landlord as tenant.

                                       36
<PAGE>

                   NOTICE REGARDING TENANT'S MOVING IN OR OUT

                                  PARAGRAPH 45

     Two days prior to any move into or out of the Premises, Tenant must notify
National Business Parks, as Agent for College Road Associates, of the following:
the name of the Moving Company, Moving Company representative in charge of the
move, and Moving Company's phone number. All moves must be done during the work
week (Monday through Friday, inclusive between the hours of 7:30 AM. and 4:30
P.M.). No elevators will be available Saturday, Sunday or holidays or after 4:30
P.M. on other days. The insurance evidence in the form required by Paragraph 19
hereof must be delivered to Landlord prior to commencement of the Tenant's move
into or out of the Premises.

                     OPTION TO EXPAND FIRST AVAILABLE SPACE

                                  PARAGRAPH 46

     Tenant shall have the option to expand into space when it first becomes
vacant ("Expansion Space") in the Building upon that Expansion Space becoming
vacant by giving Landlord notice in the manner hereinafter set forth on the
terms and conditions hereinafter provided. The notice must be given by. the
Tenant in writing to the Landlord within thirty (30) days after the later of the
Landlord giving notice that such Expansion Space is or will be vacant or the
Expansion Space actually becoming vacant. Time is of the essence. The Basic Rent
for such Expansion Space will be fair market rent for comparable space in the
Princeton area. The Base Year for the initial term for the Expansion Space will
be the first calendar year that the Expansion Space is leased by Tenant from
Landlord. Except as herein provided in this Paragraph, the other terms of this
Lease will apply to such Expansion Space. If no renewal term commences after the
term for the Expansion Space commences, the term for the Expansion Space will
end the later of (i) the date defined in 8 of the Basic Lease Provisions or the
date the current renewal period ends or (ii) sixty (60) months from the date the
term for the Expansion Space commences. If a renewal term commences while the
Expansion Space is subject to this Lease, the initial term for the Expansion
Space will end when the Renewal term begins. Such Expansion Space leased is part
of the Premises for any renewal term. If the term for the Expansion Space ends
on a date later than the date the Lease would have terminated had there been no
Expansion Space, and no renewal term is elected which would go into effect after
the Expansion Space is occupied, the rate of Basic Rent will then be increased
for all the Premises to the highest Basic Rent for any Expansion Space for that
period of time after the date the Lease would have terminated had there been no
Expansion Space, and further, the term for all the Premises will be extended to
a date sixty (60) months from the date the term for the Expansion Space
commences.

     This is a one time option as to each space of whatever size when such space
first becomes vacant after the date of this Lease in the Building. For example,
if all space in the Building not initially the subject of this Lease becomes
vacant all at once subsequent to the date of the Lease, and none of such space
was vacant from the date of this Lease to the

                                       37
<PAGE>

date when all such space becomes vacant, then this option will apply to such
space for the period stated in the Second sentence of this Paragraph 46 and will
not apply again to any space in the Building. When a part of the space in the
Building not initially the subject of this Lease first becomes vacant after the
date of this Lease, this option will apply to such part for the period stated in
the second sentence of this Paragraph 46 and will not apply again to such part.

     An Amendment to this Lease will be made to reflect the effect of this
Paragraph 46, if the Option to Expand described in this Paragraph 46 is elected.

                             FIRST OPTION TO RENEW

                                  PARAGRAPH 47

     Upon condition that Tenant is not in default in the payment of any Rent or
other charge payable to Tenant under this Lease and not in default in the
performance of any covenant or obligation to be performed by Tenant under this
Lease and upon Tenant's giving Landlord twelve (12) months notice in writing in
the manner prescribed in Article 24 hereof prior to the expiration of the term
hereof, Tenant shall have the option to renew and extend this Lease for an
additional period of five (5) years, pursuant and subject to all terms,
covenants, provisions, and conditions of this Lease, including, without
limitation, the payment of all items of Rent as provided for hereunder, except
that the Basic Annual Rent shall be adjusted to the then prevailing fair market
rent for comparable space within Princeton Forrestal Center.

                             SECOND OPTION TO RENEW

                                  PARAGRAPH 48

Upon condition that Tenant is not in default in the payment of any Rent or other
charge payable to Tenant under this Lease and not in default in the performance
of any covenant or obligation to be performed by Tenant under this Lease and
upon condition that Tenant has exercised the renewal option granted in Paragraph
47 hereof, and upon Tenant's giving Landlord twelve (12) months notice in
writing in the manner prescribed in Article 24 hereof prior to the expiration of
the term hereof (as may be extended pursuant to Paragraph 47 hereof), Tenant
shall have the option to renew and extend this Lease for an additional period of
five (5) years, pursuant and subject to all terms, covenants, provisions, and
conditions of this Lease, including, without limitation, the payment of all
items of Rent as provided for hereunder, except that the Basic Annual Rent shall
be adjusted to the then prevailing fair market rent for comparable space within
Princeton Forrestal Center.

                                       38
<PAGE>

                                  EXHIBIT "A"

                              [MAP APPEARS HERE]

<PAGE>

                                  EXHIBIT B-1
                            LANDLORD'S WORK LETTER

     It is the intent of this Exhibit that Tenant shall be permitted reasonable
freedom in the interior design and layout of its space, consistent with
applicable building codes and sound architectural and construction practices in
first class office buildings, provided that no interference is caused to the
operation of the Building's mechanical, heating, cooling or electrical systems
or other building operations or functions, and no increase in maintenance or
utility charges will be incurred by Landlord. Any additional costs of design,
construction, operation or maintenance which results from Tenant's deviations
from Building Standard quantities or specifications shall be charged to Tenant.

     A.  IMPROVEMENTS

     1.  Landlord's Work: Landlord, at its sole cost and expense, shall furnish
         ---------------
and install in or for the benefit of the Premises pursuant to the plans and
specifications referred to below, the following:

     (a)  For divided-floor tenancies, all walls separating the Premises from
          areas or from other tenant space.

     2.  Landlord Allowance:  Landlord will contribute $15.00 per rentable
         ------------------
square foot, towards all Tenant improvements in demised premises only.

     3.  Landlord's Option for Tenant's Work:  Landlord under the terms of this
         -----------------------------------
Lease will allow Tenant to perform its own work under the following conditions:

         A)  Landlord has the exclusive option to either accept to perform the
Tenant work upon the Tenant producing competitive bids from qualified and
approved contractors, and provided the scope of the work is equal to all other
bids, or elect not to perform the work Tenant must submit to the Landlord its
lowest bid price in the following manner.

               1)  Name of the general contractor indicating a lump sum bid and
               a bid breakdown of the general contractor's sub-contractors with
               their bid price.
               Example:
                              Electrical:
                              -----------
                              Name:       Contractor
                              Bid Price:  Amount

                              HVAC:
                              ----
                              Name:       Contractor
                              Bid Price:  Amount

                                      39
<PAGE>

For the purpose of this bid, the following general contractors are here-by
approved:

     1.  Turner
     2.  Huber, Hunt & Nichols
     3.  Boys Construction Corp.
     4.  Torcon

     * Note:  Work must be performed with union labor of local jurisdiction, no
outside local jurisdiction is approved under this Lease.

          2)  Landlord maintains the exclusive right to approve or disapprove
          any of the general contractors or sub-contractors, not listed above.

          3)  Landlord's Approval:  Tenant's plan, as hereinafter defined, shall
              -------------------
          be subject to Landlord's prior written approval or disapproval within
          five days of the receipt of same. If Tenant's plan requires any
          variance or any modifications of any existing site plan, Tenant will
          be responsible for obtaining all approvals required at Tenant's sole
          cost and expense. Landlord will cooperate with Tenant in securing such
          approvals.

          4)  If Landlord elects to perform all of the Tenant work, then any
          cost above the Landlord's allowance will be paid for by the Tenant.
          Payments to the Landlord will be made as follows:

              a)  one third (1/3) at time of issuance of all building permits
              b)  one third (1/3) when the work is 50% completed
              c)  one third (1/3) upon completion less 10% retainage

          5)  Base Building Changes:  If Tenant Plan necessitates revisions in
              ---------------------
          the design of the base building or necessitates changes in the
          construction of the base building for which Landlord has previously
          contracted, Tenant shall be responsible for all costs resulting from
          such design revisions or construction changes, including but hot
          limited to architectural and engineering changes, and any special
          permits for fees attributed thereto. Before Landlord shall authorize
          such design and/or construction changes, Tenant shall pay Landlord the
          full cost attributable thereto. All costs will be paid to the Landlord
          with a 10% general condition and a 10% profit fee, above sub-
          contractors cost. Landlord will not proceed with any contract changes
          without prior written consent by Tenant and or its representative.

          6)  In the event that Tenant performs its own construction the payment
          of the Landlord's allowance will be paid to the Tenant upon the
          issuance of a final Certificate of Occupancy.

                                      40
<PAGE>

     B.  CONSTRUCTION

          1. By Tenant: If Landlord elects not to perform the construction for
the Tenant improvements, then the work may be done by the Tenant in compliance
with the following:

          a)  No such work shall proceed without Landlord's prior written
approval of (i) Tenant's contractor, if any; (ii) detailed plans and
specifications for the work which are usual and customary; and (iii) a
certificate of workman's compensation insurance in an amount and with a company
and on a form reasonably acceptable to Landlord and a certificate of insurance
in form and from an insurer reasonably acceptable to Landlord, showing Tenant or
Tenant's contractor to have in effect public liability, comprehensive general
liability and property damage insurance with limits of not less than
$1,000,000/$5,000,000 and $1,000,000 respectively. All such certificates except
worker's compensation shall be endorsed to show Landlord as an additional
insured and such insurance shall be maintained by Tenant or Tenant's contractor
at all times during the performance of Tenant's work.

          b)  All such work shall be done in conformity with applicable codes
and regulations of governmental authorities having jurisdiction over the
Building and Premises and with valid building permits and other authorizations
from appropriate governmental agencies when required shall be obtained by
Landlord's representative at Tenant's sole expense. Any work not being performed
by Landlord, and not acceptable to the appropriate governmental agencies or not
reasonably satisfactory to Landlord, shall be promptly replaced at Tenant's
expense. Notwithstanding any failure by Landlord to object to any such work,
Landlord shall have no responsibility therefore, except for the negligence or
willful misconduct of Landlord. Tenant agrees to save and hold Landlord harmless
for said work as provided in the Lease.

          c)  Tenant and Tenant's contractors shall abide by all safety and
construction laws, ordinances, rules and regulations. All work and deliveries
shall be scheduled through Landlord. Entry by Tenant's contractors shall be
deemed to be under all the terms, covenants, provisions and conditions of the
Lease. All Tenant's materials, work, installations and decorations of any nature
brought upon or installed in the Premises before the Commencement Date shall be
at Tenant's risk, and neither Landlord nor any party acting on Landlord's behalf
shall be responsible for any damage thereto or loss or destruction thereof.
Tenant shall not employ any contractor who in Landlord's opinion may prejudice
Landlord's negotiations or relationships with Landlord's contractors or
subcontractors or the negotiations or relationship of those contractors or
subcontractors with their employees, or may disturb harmonious labor relations.

          d)  Tenant shall reimburse Landlord for any actual, direct, and
reasonable extra expenses incurred by Landlord by reason of faulty work done by
Tenant or its contractors, or by reason of delays caused by such work, or by
reason of cleanup which fails to comply with Landlord's rules and regulations,
or by reason of building use outside normal working hours.

          e)  In addition to the sums to be paid to the Landlord pursuant to the
above, Tenant shall pay to Landlord a building service fee of ten percent (10%)
of the total

                                       41
<PAGE>

cost of Tenant's work not performed by Landlord. Such building service fee shall
be paid in the same manner as indicated in A-4 (above).

         f)  Tenant's contractors shall not post any signs on any part of the
Building or the Premises.

         g)  Tenant shall, upon Landlord's written request, provide Landlord
with copies of bills and invoices for the cost of Tenant's Work hereunder,
performed by Tenant or Tenant's contractors.

     2.  Tenant's Option to Use Landlord's Contractor: Tenant may elect to have
any of the work described above done by Landlord's contractor at Tenant's
expense.

     3.  Changes:  If there are any changes requested by Tenant, after approval
of Tenant's Plan, Tenant shall be responsible for costs including permits and
fees, architectural, engineering and related design expenses resulting from such
changes. No such changes shall be made without prior written approval of
Landlord. Landlord shall not be responsible for delay in occupancy by Tenant
because of changes to plans after approval by Tenant as outlined above. Upon
completion of such revised working drawings and specifications, Landlord shall
notify Tenant in writing of the cost which will be chargeable to Tenant by
reason of such change, addition or deletion. Tenant shall, within (5) business
days, notify Landlord in writing whether it desires to proceed with such change,
addition or deletion. In the absence of such written authorization and payment
in full of the total costs of such change, addition or deletion, Landlord shall
not be obligated to continue work on Tenant's Premises and may suspend work and
Tenant shall be responsible and chargeable for any and all delays in the
completion of the Premises resulting therefrom.

     4.  Tenant's Inspection:  Tenant is authorized by Landlord to make periodic
inspections of the Premises during construction provided that such inspections
are made during reasonable business hours and that Tenant is accompanied by a
representative of the Landlord. Tenant shall advise Landlord immediately in
writing of any objection to the performance of Tenant's Work.

     5.  If the Tenant's Work is done by other than Landlord, the term of this
Lease shall commence on the earlier of (a) the Target Commencement Date as shown
in Item 9 of the Basic Lease Provisions or (b) such earlier date as Tenant is
able to take possession of and is able to use the premises as a research
laboratory (in no event later than January 1, 1999).

     C.  ACCEPTANCE OF PREMISES

          When Landlord's Work and Tenant's Work is substantially completed in
accordance with Tenant's Plan (except for the punch list items) and a Temporary
Certificate of Occupancy is issued, the Premises shall be considered acceptable
for occupancy. Within five (5) business days of Landlord's notice that
Landlord's Work and Tenant's Work has been substantially completed, Tenant shall
inspect the Premises in the presence of Landlord

                                       42
<PAGE>

and Landlord's contractor in order to establish a punch list of items to be
completed or corrected.

     D.   RESPONSIBILITY FOR DELAYS

          If Tenant shall cause any delay in the construction of the Premises,
whether reason of any failure by Tenant to comply with the applicable time
schedule set forth in Paragraph B-5, or by Tenant's requirement of materials or
installations different from the Building Standard, or by delays in performance
of completion by a party employed by Tenant, or by reason of building code
problems arising from Tenant's design, or by reason of changes in the work
ordered by Tenant, then notwithstanding the provisions of the Lease or any other
provision of this Exhibit, any such delay in completing the Premises shall not
in any manner affect the Lease Commencement Date of the Tenant's liability for
the payment of rent set forth in the Lease.

     E.   INCORPORATED OF LEASE

          This Agreement is, and shall be incorporated by reference in the Lease
and all of the terms and provisions of said Lease are and shall be incorporated
herein by this reference.

     F.   BUILDING STANDARD ALLOWANCES

          Landlord, at Landlord's expense, except as otherwise expressly
specified in this Exhibit B and in the foregoing Lease, shall furnish and
install in and to the Premises the following, all of which shall be of material,
manufacture, design, capacity, finish and color of the Building Standard adopted
by Landlord for the Building in accordance with the Tenant's Plan.

     G.   ELECTRICAL CONSUMPTION CALCULATION

          If Tenant's electrical requirements exceed power designed to be
provided to the Premises, in order to accurately calculate the power consumed by
Tenant, it is a requirement of this Lease that the electrical design will
incorporate a check meter in order to properly calculate the power usage. The
Landlord will be consulted as to the type of meter required. All associated
cost(s) are inclusive of Tenant's Workletter Allowance.

     H.   FINAL PAYMENT OF EXCESS COSTS

          If prior to Tenant's occupancy of the Premises there is a default by
Tenant in payment of the sum it owes Landlord for the construction of the
Premises or other cost of charges stated herein, Landlord shall, in addition to
all other legally allowable remedies, have the same rights as in the case of
default in rent under the Lease. However, Landlord must provide Tenant with
written notice of such default, and Tenant shall have the appropriate time
periods to cure such default as detailed in the Lease.

                                       43
<PAGE>

                                  EXHIBIT B-2
                               BUILDING STANDARD
                                   300 SERIES

1.   PARTITIONS

     (a)       Partitions within the Demised Premises shall have 5/8" gypsum
               board on each side of 2-1/2" metal studs, 24" on center, taped
               and spackled, to underside of finished ceiling. Partitions
               between the Demised Premises and corridor(s) and between the
               Demised Premises, any adjacent space shall have 5/8" fire code
               gypsum board, taped and spackled, on each side of 3-1/2" metal
               studs, 24" on center. Demising partitions and corridor partitions
               to have 1-1/2" (full thick) sound deadening insulation installed
               within from floor to underside of floor above.

     (b)       There will be no jogs, curves or angles in any partition.

     (c)       Vinyl base 4" high to be on all partitioning and existing walls
               and columns.

2.   DOORS

     (a)       All frames to be 16 gauge, pressed steel, painted.

     (b)       Doors within Demised Premises to be 3'-0" x 7'-0" nominal x 1-
               3/4" solid core oak, rift cut, matched finish. Doors to have fire
               rating as required by applicable codes.

3.   HARDWARE

     (a)       Cylindrical latch sets, standard weight, on individual office
               doors within the Demised Premises.

     (b)       Cylindrical lock sets, heavy duty, and closers on doors from
               corridor(s) on Demised Premises.

     (c)       Lock sets and latch sets to be Schlage, Sargent, Yale, Russwin or
               equal, as selected by Landlord.

     (d)       All lock sets shall be keyed to the building master key system.

                                       44
<PAGE>

4.   ACOUSTICAL CEILINGS

     (a)       Lay-in acoustic tile ceilings, within Demised Premises, shall be
               24" x 48" regressed white mineral fiber, textured panels with
               white recessed "T" - spline, as selected by Landlord.

     (b)       Ceiling heights within Demised Premises to be nominal 9'-0".

     (c)       Direction of ceiling-grid to be as determined by Landlord.

5.   FLOORING

     Building standard carpet to be in all tenant areas where vinyl composition
     tile is not installed. All carpets will be selected from Landlord's
     samples, or of equal quality.

6.   PAINTING

     (a)       Interior wall surfaces of gypsum board shall receive two (2)
               coats of flat latex paint, colors to be selected by Tenant from
               Landlord's samples.

     (b)       All interior ferrous metal surfaces shall receive two (2) coats
               of alkyd semigloss enamel paint over shop-applied primer.

     (c)       All wood doors to receive one (1) coat of sealer and two (2)
               coats of clear polyurethane satin varnish.

     (d)       Paint manufacturers to be Sherwin Williams, or approved equal, as
               selected by Landlord.

7.   WINDOW COVERING

     All exterior windows to receive building standard, narrow, horizontal
aluminum slat blinds, Levelor or equal, as selected by Landlord.

8.   ELECTRICAL SPECIFICATIONS

     (a)       Lighting - Provide 2' x 4' 3L - high efficiency open deep cell
               fixtures in regressed aluminum frame with air return feature.

     (b)       Power - Wall mounted duplex receptacles must meet all applicable
               codes.

     (c)       The average electric load of the Demised Premises shall not
               exceed five (5) watts per square foot for lighting and power in
               office areas.  Landlord will provide available service of 200A
               277/480V 3 phase, for Tenant's exclusive use. All other
               switchgear required is a function

                                      45
<PAGE>

               of the work letter allowance.

     (d)       Landlord shall initially provide and install lamps and ballasts.
               Replacement of same shall be by Landlord, at Tenant's expense.

9.   FIRE AND LIFE SAFETY FEATURES

     (a)       The Building is fully sprinklered in all areas.

     (b)       Fire Alarm System consisting of manual pull boxes, annunciators,
               alarm bells, control panel, etc. shall be required per code.

     (c)       Smoke detectors, ionization-type, in corridors, Tenant's space,
               electrical equipment rooms, elevator machine rooms and ductwork
               where the air quality is over 15,000 CEM. Firestats in the
               ductwork where air quality is less than 15,000 CEM.

     (d)       Battery back-up shall be required in the Building to operate all
               emergency and exit lighting fixtures in public areas and fire
               alarm system.

10.  TELEPHONE WORK

     (a)       The Landlord shall arrange with New Jersey Bell Telephone Company
               for telephone service within the equipment room in the Building's
               core.

     (b)       All telephone work and wiring in partitions, floors and ceilings
               to be paid for by Tenant as arranged for by Tenant with any
               qualified installer selected by Tenant but approved by Landlord.
               Landlord will coordinate work with other trades as required.
               Completion or non-completion of the telephone work will not delay
               Tenant's acceptance of the Demised Premises or the payment of
               Rent. All electrical load centers, special wiring and plywood
               supplied by Landlord for telephone equipment shall be an extra
               cost to be paid by Tenant. Telephone company work is to meet all
               prevailing codes.

11.  HVAC SPECIFICATIONS

     (a)       Heating, ventilation and air-conditioning system shall be capable
               of maintaining the following interior conditions, subject to
               governmental regulations:

               Summer - 75 degrees F (+2 degrees F) dry bulb and 50% relative
               humidity, when outside temperature is 90 degrees F dry bulb and
               75 degrees wet bulb.

                                       46
<PAGE>

               Winter - 68 degrees F when outside temperature is 14 degrees F.

     (b)       The VAV system with roof top A/C unit will have automatic
               thermostats mounted in the rooms or open spaces within the
               Demised Premises.

     (c)       The VAV units are connected to roof top A/C units with filters,
               mixing dampers and fan motor.

     (d)       Tenant override timers and running hour meter will be provided in
               electrical closet for after hours use.

     (e)       The air supply distribution of the HVAC system for the Demised
               Premises shall be based on five (5) watts per square foot of
               total electrical load for all purposes. Occupancy rate is based
               on one (1) person per 200 square feet.

     (f)       All heating will be provided from the perimeter base board
               heaters via solid state controllers, from Building central
               system.

     (g)       The control system for the heating will be by means of electric
               thermostats mounted in the rooms or open spaces within the
               Demised Premises as described in (11 b) interfaced with solar &
               ambient outdoor temperature sensors.

     (h)       Zoning within Tenant's Demised Premises shall provide interior
               and perimeter zones. The number of zones, as determined by
               Landlord, shall be based on orientation and total area occupied
               with average zones as follows:

               Perimeter of areas - one (1) zone per 1,200 square feet

               Interior areas - one (1) zone per 2,000 square feet

               An average of 1 CFM per square foot will be delivered by the HVAC
               system within the Demised Premises. Diffusers supplying air will
               be spaced at 1 per 225 square feet.

     (i)       If Tenant's equipment (i.e. computers, business machines, etc.)
               or special uses (i.e. conference rooms, mailrooms, lunch rooms,
               etc.) requires air-conditioning above and beyond Building
               Standard, as outlined, said additional air conditioning
               (including cost of operation as stipulated in the Lease) shall be
               paid for by Tenant. Any special exhaust requirements will also be
               paid for by Tenant.

                                       47
<PAGE>

                                  EXHIBIT "C"

                         COMMENCEMENT DATE MEMORANDUM

     THIS AGREEMENT made the ___ day of _______, 1998, by and between COLLEGE:
ROAD ASSOCIATES, LIMITED PARTNERSHIP ("Landlord") and ______________ with an
office at _______________, Princeton, New Jersey 08540 ("Tenant").

                                  WITNESSETH:

     WHEREAS, Landlord and Tenant entered into a lease dated ___________
("Lease") setting forth the terms of occupancy by Tenant of a portion of a
Building located at ___________ Princeton, New Jersey; and

     WHEREAS, the Lease is for a term of _____________, with the "Target
Commencement Date" of the term being defined as __________ in Basic Lease
Provisions of the Lease; and

     WHEREAS, it has been determined that ________________ is the actual
Commencement Date of the Lease.

     NOW, THEREFORE, in consideration of the premises and the covenants
hereinafter set forth, it is agreed:

     1.  The actual Commencement Date of the term of the Lease is ____________
and the termination date thereof is _______________

     2.  This agreement is executed by the parties for the purpose of providing
a record of the commencement and termination dates of the term of the Lease.

                                      48
<PAGE>

     IN WITNESS WHEREOF, the parties hereto have duly executed this instrument
as of the day and year first above written.

                                              COLLEGE ROAD ASSOCIATES,
                                              LIMITED PARTNERSHIP

                                              BY:  Z FORRESTAL CENTER, L.P.
                                                   Its Managing General Partner

                                              BY:  Z FORRESTAL CORP.,
                                                   Its General Partner

ATTEST

BY:________________________                   BY:_______________________________
    Name:                                         Name:  John Zirinsky
    Title:                                        Title:  President

ATTEST

BY:________________________                   BY:_______________________________
    Name:                                         Name:
    Title:                                        Title:

                                      49
<PAGE>

                             RULES AND REGULATIONS
                             ---------------------
                                   Exhibit D

1.  The sidewalks, halls, passages, elevators and stairways shall not be
obstructed by any of the tenants nor used by them for any other purpose than for
ingress and egress to and from their respective offices, nor shall they be used
as a waiting or lounging place for tenant's employees or those having business
with tenants. The halls, passages, elevators, stairways and roofs are not for
the use of the general public, and Landlord retains in all cases the right to
control and prevent access to any part of said Building of all persons whose
presence, in the judgement of Landlord or Landlord's employees, may be
prejudicial to the safety, character, reputation or interests of the Building
and its tenants. In case of invasion, mob, riot, public excitement or other
commotion, Landlord reserves the right to prevent access to the Building during
the continuance of same by closing the doors or otherwise, for the safety of
tenants and the protection of property in said Building. During other than
business hours, access to the Building may also be refused, unless the person
seeking admission is known by Landlord's agent in charge to have the right to
enter the Premises therein or is properly identified. In addition, the
production of a key to such premises may be required. Landlord shall in no case
be liable in damages for the admission or exclusion of any person from said
Building.

2.  The floors, walls, partitions, skylights, transoms that reflect or admit
light into passageways or into any place in said Building shall not be covered
or obstructed by any of the tenants. The toilet-rooms, sinks and other water
apparatus shall hot be used for any purposes other than those for which they
were constructed, and no sweepings, rubbish, rags, ashes, chemicals or refuse
shall be thrown or placed therein. Any damage resulting from such misuses or
abuse shall be borne and immediately paid by Tenant by whom or by whose
employees it shall have been caused.

3.  Nothing shall be placed by tenants or their employees on the outside of the
Building.

4.  No sign, advertisement or notice shall be inscribed, painted or affixed on
any part of the outside or inside of said Building, unless of such character,
color, size and material and in such places as shall be first designated by
Landlord in writing. A sign painter authorized by Landlord will do such work at
Tenant's expense.

5.  Tenant will see that the windows are closed and the doors securely locked
each day before leaving the Building. Shades shall be of the material, style,
form and color adopted by Landlord for the Building, and no tenant shall put up
any that do not conform to such standards. Tenant shall have the right to remove
such shades at the expiration of the lease.

6.  Tenant, their employees or others shall not make or commit any improper
noises or disturbances of any kind in the Building, nor smoke in the elevators,
mark or defile the elevators, bathrooms or interfere in any way with other
tenants or those having business in the Building. Tenants shall be liable for
all damage to the Building done by their employees. Cigar & pipe smoking will
not be permitted anywhere in the Building.

                                       50
<PAGE>

7.  No carpet, rug or other article shall be hung or shaken out of any window,
and nothing shall be thrown by tenants or tenants' employees nor be allowed by
them to drop out of the windows or doors or down the passages or skylights of
the Building; and no tenant shall sweep or throw or permit to be swept or thrown
from the Premises any dirt or other substance into any of the corridors or
halls, elevators or stairways of the Building, or into any of the lightshafts or
ventilators thereof.

8.  No animals shall be kept in or about the Premises, except for small
laboratory animals.

9.  If the tenants desire to introduce signalling, telegraphic, telephonic or
other wires and instruments, Landlord will direct the electricians as to where
and how the same are to be placed; and, without such direction, no placing
boring or cutting for wires will be permitted. Landlord retains in all cases the
right to require the placing and using of such electrical protecting devices to
prevent the transmission of excessive currents of electricity into or through
the Building, to require the changing of wires and of their placing an
arrangement underground or otherwise as Landlord may direct, and further to
require compliance on the part of all using or seeking access to such wires with
such rules as Landlord may establish thereto; and, in the event of noncompliance
by tenants or by those furnishing service by or using such wires or by others
with the directions, requirements or rules, Landlord shall have the right to
immediately cut, displace and prevent the use of such wires. Notice requiring
such changing of wires and their replacing and rearrangement given by Landlord
to any company or individual furnishing service by means of such wires to any
tenant shall be regarded as notice to such tenants and shall take effect
immediately. All wires used by tenants must be clearly tagged at the
distributing boards and junction boxes and elsewhere in the Building and with
the number of the office to which said wires lead and the purpose for which said
wires respectively are used, together with the names of the company operating
same.

10. A directory in a conspicuous place on the first floor, with the names of
tenants, will be provided by Landlord at Landlord's expense.

11. No varnish, stain, paint, linoleum, oil-cloth, rubber or other air-tight
covering shall be laid or put upon the floors; nor shall articles be fastened to
or holes drilled or nails or screws driven into walls, doors or partitions; nor
shall the walls, doors or partitions be painted, papered or otherwise covered or
in any way marked or broken; nor shall any tenant use any other method of
heating than that provided by Landlord; without the written consent of Landlord,
which consent shall not be unreasonably withheld.

12. The delivery of materials and other supplies to tenants in the Building
will be permitted only under the direction, control and supervision of the
Landlord.

13. The use of rooms as sleeping apartments is prohibited.

14. All entrance doors leading from the hallways are to be kept closed at all
times.

15. For the protection of tenants, the Landlord reserves the right to refuse the

                                      51
<PAGE>

admittance to the Building between the hours of 5:30 p.m. and 8:00 a.m., Monday
through Friday, and from 1:00 p.m. Saturday to 8:00 a.m. Monday to any person
not producing a key to such Tenant's office or suite and a pass issued by
building management upon the direction of the tenant. Tenants will instruct the
Building manager from time to time as to the number of persons to whom they
desire passes issued for this purpose. It will be the responsibility of the
Tenant to pick up any pass and key whenever the employment of the passholder is
discontinued.

16.  Tenants must use designated parking lots only during hours of building
operation. Tenant parking is restricted to main lots and is not permitted in any
other area whatsoever including visitor, delivery or fire lane areas. It is
expressly prohibited to allow overnight parking or storage of vehicles used by
`employees or in the course of business without prior written consent of
Landlord.

Violation of this parking regulation will result in removal of the vehicle at
the sole cost of tenant.

17.  Tenants must adhere to all recycling mandates (as they may be required by
local and state laws), and Landlord's existing established procedure (s).

18.  No smoking is permitted in the Premises or any other part of the Building.

19.  No vending machine of any type are permitted in the Premises without the
prior written consent of the Landlord.

20.  All deliveries to and/or from the Building must be coordinated with the
Building's Management.

                                      52
<PAGE>

                                   EXHIBIT E
                                COLLEGE PARK AT
                           PRINCETON FORRESTAL CENTER

                           JANITORIAL SPECIFICATIONS

General Cleaning
----------------

     Cleaning Services provided five (5) days per week unless otherwise
     specified.

     Cleaning hours Monday through Friday, between 6:00 p.m. and before 8:00
     a.m. of the following day.

     On the last day of the week work will be done after 6:00 p.m. Friday, but
     before 8:00 a.m. Monday.

     No cleaning on holidays.

I.   Office Area
     -----------

     Furniture and fixtures within reach will be dusted and desk tops will be
     wiped clean.  However, desks with loose papers on top will not be cleaned.

     Window sills and baseboards to be dusted and washed when necessary.

     Office wastepaper baskets will be emptied.

     Cartons or refuse in excess of that which can be placed in wastebaskets
     will not be removed. Tenants are required to place such unusual refuse in
     trash cans.

     Cleaner will not remove or clean tea or coffee cups or similar containers;
     also, if such liquids are spilled in wastebaskets, the wastebaskets will be
     emptied but not otherwise cleaned. All kitchen cleaning by Tenant.

     Carpets will be vacuumed nightly.

     All tile floors will be vacuumed nightly and wet mopped weekly.

     Wipe clean all glass, brass and other bright work weekly.

     Dust all pictures, charts, wall hangings monthly that are not reached in
     nightly cleaning.

     Dust all vertical surfaces to include doors, bucks and partitions monthly.

     Dust all ventilating louvers and other such installations monthly.

                                      53
<PAGE>

II.  Lavatories
     ----------

     All lavatory floors to be swept and washed with disinfectant nightly.

     Tile walls and dividing partitions to be washed and disinfected weekly.

     Basins, bowls, urinals to be washed and disinfected daily.

     Mirrors, shelves, plumbing work, bright work, and enamel surfaces cleaned
     nightly.

     Waste receptacles will be emptied and cleaned and wash dispensaries to be
     filled with appropriate tissues, towels, and soap nightly.

III. Main Lobby Elevators, Building Exterior and Corridors
     -----------------------------------------------------

     Wipe and wash all floors in Main Lobby nightly.

     Wipe and/or vacuum elevator floor nightly.

     Polish floors weekly in elevator.

IV:  All windows interior and exterior will be cleaned once a year.

V:   Tenant will comply fully with the New Jersey State Recycling Mandates.

VI:  Tenant is responsible for the cleaning of Tenant's laboratory area(s).

                                      54
<PAGE>

                                  EXHIBIT "F"
                             Model Letter of Credit
                             ----------------------

{Insert name and address of issuing bank}
 ---------------------------------------

{Insert date}

IRREVOCABLE LETTER OF CREDIT NO. {Insert number}
{Insert name and address of owner}

Dear Sir:
At the request and for the account of {insert name of Tenant} located at
                                       ---------------------
{insert address of Tenant} (hereinafter called "Applicant"), we hereby establish
 ------------------------
our Irrevocable Letter of Credit No. {insert number} in your favor and authorize
                                      -------------
you to draw on us up to the aggregate amount of US $ {insert amount of Letter of
                                                      --------------------------
Credit} available by your draft(s) at sight drawn on us and accompanied by the
------
following:

A written statement by you that:
     (i)  "Applicant is in default under that certain lease, dated as of {insert
                                                                          ------
          date of lease} between you, as Landlord, and Applicant, as Tenant (the
          -------------
          `Lease');" or

     (ii) "Applicant has failed to deliver timely a renewal Letter of Credit as
          provided in the Lease."

This Irrevocable Letter of Credit will be duly honored by us at sight upon
delivery of the statement set forth above without inquiry as to the accuracy of
such statement and regardless of whether Applicant disputes the content of such
statement.

We hereby engage with you that all drafts drawn under and in compliance with the
terms of this Irrevocable Letter of Credit will be duly honored by us if
presented at {insert address of issuing bank} no later than {insert expiration
              ------------------------------                 -----------------
date of Letter of Credit}, it being a condition of this Irrevocable Letter of
------------------------
Credit that it shall be automatically extended for periods of at least one year
from the present and each future expiration date unless, at least sixty (60)
days prior to the relevant expiration date, we notify you, by certified mail,
return receipt requested, that we elect not to extend this Irrevocable Letter of
Credit for any additional period.

This Irrevocable Letter of Credit is transferable at no charge to any transferee
of Landlord upon notice to the undersigned from you and such transferee.

This Irrevocable Letter of Credit is subject to the Uniform Customs and
Practices for Documentary Credits (1983-Rev) International Chamber of Commerce
Publication #400.

Sincerely yours,
{Insert authorized signature}
 ---------------------------

                                      55

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00002-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00002-of-00352.parquet"}]]