Document:

ARTICLES OF AMENDMENT
                                       TO
                            ARTICLES OF INCORPORATION
                                       OF
                          CATALYST COMMUNICATIONS, INC.

Articles I and IV of the Articles of Incorporation  of Catalyst  Communications,
Inc., a Utah  Corporation  (the  "Corporation"),  is hereby further  amended and
restated in its entirety to read as follows:

                                    ARTICLE I

The name of this  Corporation  is DNAPrint  genomics,  Inc.,  formerly  known as
Catalyst Communications, Inc., and prior to December 26, 1996 known as Homestyle
Harmony, Inc., and prior to 1996 known as Aire Wrap Systems International, Inc.,
and originally incorporated as Lexington Energy, Inc.

                                   ARTICLE IV

AUTHORIZED SHARES. The Company shall have two (2) classes of shares,  that being
common stock and preferred  stock. The Company shall have the authority to issue
five hundred  million  (500,000,000)  shares of common stock with a par value of
one cent ($0.01) per share.  The Company  shall have the  authority to issue ten
million  (10,000,000)  shares of  preferred  stock  with a par value of one cent
($0.01) per share. All stock will be fully paid and nonassessable, and the stock
of this  Corporation  shall not be liable for further  call or  assessment.  The
authorized shares shall be issued at the discretion of the Directors.

The  foregoing  amendment  (the  "Amendment")  was adopted  and  approved by the
written consent,  dated and effective July 17, 2000, of the holders of more than
a majority  of the  Corporation's  192,360,986  shares of $0.01 (one  tenth) par
value voting common stock then  outstanding in accordance with the provisions of
Section 16-10a-704 of the Utah Revised Business  Corporation Act. The holders of
the  192,360,986  shares of $0.01 (one tenth) par value voting common stock were
the only  voting  group  entitled  to vote on the  Amendment,  and each of these
shares was entitled to one vote.  The total number of undisputed  votes cast for
the Amendment by this voting group was 100,667,772, and the number of votes cast
for the  Amendment  by such voting  group was  sufficient  for  approval by that
voting group.

IN WITNESS WHEREOF, these Articles of Amendment are executed on July 17, 2000.

CATALYST COMMUNICATIONS, INC.

By:      /s/Carl L. Smith
         Carl L. Smith

         Chairman and Chief Executive OfficerSUPPLY AND LICENSE AGREEMENT FOR AUTOMATED SNP ANALYSIS

         THIS  AGREEMENT,  made this 15th day of September 2000 (the  "Effective
Date"), is between Orchid Biosciences,  Inc., a Delaware  corporation,  having a
principal  place of  business at 303 College  Road East,  Princeton,  New Jersey
08543 ("Orchid"),  and DNAPrint Genomics, Inc., a Florida corporation,  having a
principal place of business at 1748 Independence Boulevard,  Suite D1, Sarasota,
Florida 34234 ("DNAPrint"). The parties agree as follows:

1        Definitions
         In this Agreement:

1.1  "Formatting"  means the custom design of PCR and SNP-IT primers and quality
     control  of  the   primers  for   amplification   and   subsequent   SNP-IT
     functionality.

1.2  "Genotyping Services" means the practice of Primer Extension on behalf of a
     third party and the  compilation  and reporting of the results to the third
     party.

1.3  "Improvements"  means any and all new and useful  processes,  manufactures,
     compositions  of matter or  methods  of use,  first  conceived,  reduced to
     practice or developed during the term of this Agreement, by DNAPrint or its
     employees, consultants or contractors.

1.4  "Know-How" means Orchid's proprietary  information as of the Effective Date
     for performing automated SNP-IT.

1.5  "Orchid Trademarks" means the marks listed in attached Schedule 1.5 and any
     stylized version or variation thereof.

1.6  "Primer Extension" means a nucleic acid template-dependent primer extension
     reaction  to  determine  the  identity  of a  single  nucleotide  base at a
     specific position in a nucleic acid of interest.

1.7  "DNAPrint's  SNPstream  Instrument" means the SNPstream Instrument DNAPrint
     is purchasing from Orchid to be located at ________.

1.8  "SNP Assay Kit" means the SNPware(TM)  preformatted  consumable  assay kits
     containing  validated and quality  controlled  reagents or similar kits for
     genotyping.

1.9  "SNP Identification  Technology" or "SNP-IT" means an assay that identifies
     one and only one base position of a target nucleic acid.

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2        Supply Of SNP Assay Kits

2.1  During  the term of this  Agreement,  Orchid  will  sell to  DNAPrint,  and
     DNAPrint will purchase from Orchid,  all of DNAPrint's  requirements of SNP
     Assay Kits.

2.2  Orchid  will  provide  Formatting  with its  supply  of SNP  Assay  Kits to
     DNAPrint in accordance with section 3. DNAPrint may not order any SNP Assay
     Kit until Orchid completes  Formatting for the particular  SNP(s) which the
     SNP Assay Kit is intended to identify.

2.3  DNAPrint will issue written  purchase  orders to Orchid for SNP Assay Kits.
     The  purchase  orders  are  subject  to the  terms and  provisions  of this
     Agreement  which,  if other or different than those of the purchase  order,
     will be  controlling  even if the purchase  order is accepted and filled by
     Orchid.

2.4  Orchid will use all commercially  reasonable  efforts to supply  DNAPrint's
     reasonable requirements of forecast SNP Assay Kits.

2.5  All purchase orders will be accepted unless Orchid notifies DNAPrint within
     ten (10) business days of receipt of the purchase  order that Orchid cannot
     fill the purchase order.

2.6  DNAPrint  may defer or cancel  delivery  of SNP Assay Kits  specified  in a
     purchase order by notifying Orchid at least twenty (20) business days prior
     to the requested  delivery date. All permitted SNP Assay Kit  cancellations
     are subject to  cancellation  charges of ten percent  (10%) of the purchase
     price.  A request by DNAPrint to defer  delivery of SNP Assay Kits for more
     than sixty  (60) days  after the date  provided  on the  purchase  order is
     considered a cancellation for the purposes of this paragraph.

3        Formatting

3.1  SNP  Assay  Kits  supplied  under  this  Agreement  will be  Formatted  for
     particular SNPs of interest to DNAPrint.

3.2  Accordingly,  prior to  submitting  a  purchase  order for a SNP Assay Kit,
     DNAPrint  will  describe  to Orchid the SNP of  interest  for which the SNP
     Assay Kit will be Formatted.

3.3  With respect to a submitted SNP sequence  which (i) includes at least fifty
     (50)  flanking  bases both  upstream and  downstream of the SNP of interest
     (e.g.  greater  than 100 base pairs of  interest),  (ii) is at least  fifty
     (50%) known (e.g.  no more than five (5) "N" per 101 base  sequence,  (iii)
     has a GC content  between  thirty five (35) and seventy (70) percent,  (iv)
     has a quality  score of PHRED 20 or higher,  and (v) is annotated  with SNP
     and/or  insertion or deletion  sites,  Orchid will provide the  Formatting,
     using its standard procedures, free of charge. Orchid's standard Formatting
     procedures involve _____.

3.4  In the event that Orchid is unable to properly  Format SNP Assay Kits for a
     submitted  SNP  of  interest  using  its  standard  Formatting  procedures,
     DNAPrint  may  request  Orchid  to use more  than its  standard  Formatting
     procedures to attempt to properly Format SNP Assay Kits.  DNAPrint will pay
     Orchid two thousand dollars ($2,000) per man-day for its efforts beyond its
     standard formatting procedures.

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3.5  Both Orchid and DNAPrint  recognize that Formatting for a particular SNP of
     interest is inexact and may be  commercially  unreasonable  or  impossible.
     Therefore,  neither  DNAPrint nor Orchid expect Orchid to be able to Format
     for more than X% of the SNPs of interest submitted.  In the event, however,
     Orchid is unable to Format at least X% of the SNPs DNAPrint  submits,  then
     the  Minimum  Amount of SNP Assay Kits  DNAPrint is  committed  to purchase
     under  paragraph 4.1 will be reduced by a factor equal to the percentage of
     SNPs  Orchid was unable to Format  (Y%)  divided  by X% (i.e.  the  Minimum
     Amount will be reduced in a amount equal to Y%/X% x the Minimum Amount).

4    Minimum

4.1  DNAPrint will purchase, at a minimum, SNP Assay Kits to perform two hundred
     thousand  (200,000)  genotypes  during  the  term  of this  Agreement  (the
     "Minimum Amount").

4.2  In the event the quantity of SNP Assay Kits actually  purchased by DNAPrint
     is less than the Minimum  Amount,  DNAPrint  will pay to Orchid a Shortfall
     Fee equal to fifty percent (50%) of the purchase price of the difference in
     the Minimum Amount and the amount of SNP Assay Kits it did purchase.

4.3  DNAPrint  will pay the  Shortfall  Fee to Orchid within thirty (30) days of
     the expiration or termination date of this Agreement.

4.4  In the event  Orchid is unable  to fill  DNAPrint's  purchase  order on the
     delivery date set forth in the purchase order, then the Minimum Amount will
     be reduced by the amount of SNP Assay Kits Orchid is unable to supply.

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5        Delivery

5.1  Orchid will use reasonable efforts to deliver to DNAPrint SNP Assay Kits on
     or before the date requested in DNAPrint's purchase order, but will have no
     obligation to deliver SNP Assay Kits in less than twenty (20) business days
     from receipt of the purchase order.

5.2  Orchid will ship SNP Assay Kits F.O.B. Orchid's manufacturing plant, or its
     supplier's plant,  freight prepaid,  to the address specified in DNAPrint's
     purchase  order.  DNAPrint  will  be  invoiced  for all  shipping  charges,
     freight,  insurance,  special  handling (where required) and similar costs,
     import permits and duties (if applicable) and all taxes assessed. Title and
     the risk of loss with  respect to SNP Assay Kits  transfer  to  DNAPrint at
     this time.

5.3  DNAPrint,  in consultation with Orchid,  will select the carrier or freight
     forwarder which will be at all times an agent of DNAPrint.  Orchid will not
     be liable for any damages,  loss or penalty for delay in delivery caused by
     the carrier or freight  forwarder  or for failure of the carrier or freight
     forwarder to give DNAPrint notice of any delay.

6        Price and Payment

6.1  The purchase  price for SNP Assay Kits to be delivered by Orchid under this
     Agreement  to  DNAPrint  will be  equivalent  to seventy  cents  ($.70) per
     genotype.

6.2  All payments for SNP Assay Kits will be made in United  States  Dollars and
     within thirty (30) days of receipt of Orchid's invoice therefor.

6.3  Orchid may add an interest  charge equal to 1/1/2% per month (18% per year)
     on any amounts payable by DNAPrint that remain unpaid after the payment due
     date.

7        Forecasts and Allocation

7.1  Within thirty (30) days of the Effective  Date of this Agreement and at the
     beginning of each calendar quarter thereafter, DNAPrint will provide Orchid
     with a written  forecast  of its  requirements  for SNP Assay  Kits for the
     remainder of the term of this  Agreement.  The first calendar  quarter of a
     forecast  represents a firm  commitment  to purchase such SNP Assay Kits in
     that quarter (subject to the cancellation provisions of paragraph 2.6). The
     remaining portion of each forecast  represents a non-binding  projection on
     which Orchid will base its material procurement and manufacturing plans.

7.2  In the event that  demand  for any SNP Assay Kit should at any time  exceed
     Orchid's capacity to fill and deliver all of its customer's orders (and its
     own need for SNP Assay  Kits),  Orchid will  notify  DNAPrint of the excess
     demand.  Until such time as the excess demand  abates or Orchid's  capacity
     becomes  sufficient  to meet  such  demand,  Orchid  will have the right to
     equitably  allocate,  in any manner it deems just and fair,  its  available
     supplies,  manufacturing  capacity,  inventory and other  resources,  among
     DNAPrint,  itself and its other  customers,  including those not then under
     contract.

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<PAGE>

7.3  In the event  Orchid is unable,  or expects  to be  unable,  to  reasonably
     supply  DNAPrint's  requirements of forecast SNP Assay Kits for twenty (20)
     consecutive  business  days from the  delivery  date set out in  DNAPrint's
     purchase  order,  DNAPrint  may obtain  from any other  source,  reasonably
     acceptable to Orchid,  that portion of its  requirements for SNP Assay Kits
     which Orchid is unable to reasonably supply for so long as Orchid is unable
     or expects to be unable to supply that portion of DNAPrint's  requirements.
     The  alternate  source  will  supply  only SNP Assay  Kits that  conform to
     Orchid's  specifications  and are of the same or  better  quality  as those
     supplied by Orchid.  Orchid will provide DNAPrint with technical assistance
     and  information as may be reasonably  required by DNAPrint to establish an
     alternate source of SNP Assay Kits, including a license under any patent to
     which Orchid has rights to license on the method of  manufacture of the SNP
     Assay Kits or on the method of use of the SNP Assay Kits authorized in this
     Agreement.

7.4  In the event that both Orchid and sources  reasonably  acceptable to Orchid
     are unable to deliver  forecast SNP Assay Kits for thirty (30)  consecutive
     business days from the original purchase order delivery date, then DNAPrint
     at its sole  discretion may elect to terminate this Agreement upon ten (10)
     days prior written notice to Orchid. In the event DNAPrint  terminates this
     Agreement  pursuant  to this  paragraph,  DNAPrint  will be relieved of its
     obligations to purchase the Minimum Amount and to pay the Shortfall Fee.

8        Inspection and Acceptance

8.1  DNAPrint may conduct  acceptance  testing upon receipt of SNP Assay Kits to
     verify  conformance  with their  specifications.  In the absence of written
     notice to Orchid of  nonconformance  and  nonacceptance  within twenty five
     (25) business days of delivery, the SNP Assay Kits will be deemed accepted.
     Orchid  will  provide to  DNAPrint  with each SNP Assay Kit  delivery  data
     verifying the SNP Assay Kit's conformance with its specifications.

8.2  If Orchid disputes  DNAPrint's notice that a SNP Assay Kit fails to conform
     to its  specifications,  such  dispute  will be resolved by an  independent
     laboratory, selected by Orchid and reasonably acceptable to DNAPrint, whose
     determination  will be  final  and  binding.  All  fees  and  disbursements
     incurred in connection with the independent  determination will be borne by
     the party which  incorrectly  determined  that the SNP Assay Kit did or did
     not conform to its specifications.

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<PAGE>

8.3  Orchid  promptly  will  replace  any SNP  Assay Kit not  conforming  to its
     specifications,  at its expense;  or, if unable to make prompt replacement,
     refund any payment made on the  nonconforming  SNP Assay Kit. The amount of
     any  nonconforming  SNP Assay Kits that are not  replaced  will be deducted
     from the Minimum Amount.

9        Limited License

9.1  Orchid   grants  to   DNAPrint,   for  the  term  of  this   Agreement,   a
     non-transferable, non-exclusive license to use the SNP Assay Kits (provided
     under  this  Agreement)  on  DNAPrint's  SNPstream  Instrument  solely  for
     research use and only for the detection of genetic polymorphisms by SNP-IT.
     DNAPrint  may make this use only on its own behalf and in its  provision of
     Genotyping Services under this Agreement.

9.2  No other  license is intended or granted  through sale of SNP Assay Kits to
     DNAPrint.

9.3  DNAPrint may use the SNP Assay Kits only on DNAPrint's SNPstream Instrument
     and only at its facility at a location to be  specified  prior to September
     30, 2000.

9.4  DNAPrint is specifically  not authorized to, and is forbidden  from,  using
     SNP  Assay  Kits  for  diagnostic  or  therapeutic  purposes  or as  direct
     components  in the  manufacture  or use of any  diagnostic  or  therapeutic
     product.

9.5  Purchase  by DNAPrint of SNP Assay Kits does not include or carry any right
     to resell or transfer the SNP Assay Kits,  either as a stand alone  product
     or as a  component  of  another  product,  or to  disassemble  and  use any
     component or part of any SNP Assay Kit separate  from its other  components
     and parts, or to otherwise commercially exploit the SNP Assay Kits. Any use
     of SNP Assay Kits other than the  licensed  use without the prior,  express
     written authorization of Orchid is strictly prohibited.

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10       Trademarks

10.1 Orchid   grants  to   DNAPrint,   for  the  term  of  this   Agreement,   a
     non-transferable, non-exclusive license to use the Orchid Trademarks solely
     for and in connection with the marketing,  promotion,  advertisement,  sale
     and provision of Genotyping Services under this Agreement.

10.2 DNAPrint may not use the Orchid  Trademarks in connection with any products
     or services other than the Genotyping Services.

10.3 DNAPrint,  in connection with the use of the Orchid Trademarks,  will place
     adjacent  to the Orchid  Trademarks  the  appropriate  designation  "(TM)",
     "(sm)",  or "(R)" and  indicate  on all printed oR  electronic  materials a
     notice to the effect the Orchid  Trademarks  are the trademarks and service
     marks of Orchid and are used under license from Orchid.

10.4 DNAPrint  may  not use the  Orchid  Trademarks  in any  manner  that  might
     adversely  reflect  on the  image  of  quality  symbolized  by  the  Orchid
     Trademarks.

10.5 DNAPrint  acknowledges Orchid's exclusive right, title and interests in and
     to the Orchid  Trademarks,  and acknowledges that nothing in this Agreement
     or DNAPrint's use of the Orchid  Trademarks will confer to it or create any
     rights  for it in the Orchid  Trademarks  except  for the  limited  license
     expressly  provide  in  this  Agreement.  All  goodwill  symbolized  by and
     connected  with the use of the Orchid  Trademarks  will inure solely to the
     benefit of Orchid.

10.6 DNAPrint  will not use any  trademark or service  mark that is  confusingly
     similar to, or a colorable  imitation of, any Orchid  Trademark  during the
     term of this Agreement or at any time thereafter.

10.7 Except as provided in this Agreement, or with other express written consent
     of the other party, neither party will at anytime include the other parties
     name in any written  material,  marketing or advertising  brochures,  bids,
     contracts, proposals,  applications or otherwise, except as may be required
     by law, or in any way  represent or imply that the other party has endorsed
     that party or its business.

10.8 Immediately  upon  expiration or  termination  of this  Agreement,  with or
     without  reason,  DNAPrint will cease and not  thereafter use in any manner
     the Orchid Trademarks.

11       Genotyping Services

11.1 Orchid grants to DNAPrint a non-transferable, non-exclusive license for the
     term of this Agreement to provide Genotyping Services.

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11.2 DNA print has no right under this Agreement to provide Genotyping  Services
     other than solely for research use and not for  diagnostic  or  therapeutic
     purposes,  unless  permitted to do so under a separate written license from
     Orchid.

11.3 DNAPrint  will inform each third party in writing who  requests  Genotyping
     Services that the employed  Primer  Extension  Technology is proprietary to
     Orchid and that  DNAPrint is only licensed to provide  Genotyping  Services
     solely  for  research  purposes  and  not  for  diagnostic  or  therapeutic
     purposes.

11.4 DNAPrint will include in its printed and electronic marketing,  promotional
     and  advertising  materials  relating to Genotyping  Services  notification
     clearly stating  substantially  the following  information:  (i) Genotyping
     Services  are subject to  proprietary  rights of Orchid and are provided by
     DNAPrint under license from Orchid; (ii) results of the Genotyping Services
     are solely for research use and not for diagnostic or therapeutic purposes;
     and (iii)  all  warnings  and  statements  required  by  applicable  law or
     regulation,  or provided by Orchid from time to time, for  notification  to
     customers.

11.5 If  DNAPrint  considers  in its  reasonable  judgment  that any third party
     requesting  Genotyping Services intends to use, or is using, the Genotyping
     Services  not for  research  purposes,  or for  diagnostic  or  therapeutic
     purposes,  DNAPrint will not provide, and will immediately cease providing,
     any  Genotyping  Services to that third  party,  and will notify  Orchid in
     writing of the third party's name and address, the dates, types and amounts
     of Genotyping Services it provided to the third party, and acknowledge that
     it has ceased providing Genotyping Services to the third party.

11.6 In the marketing, advertising, promotion, sale or performance of Genotyping
     Services, DNAPrint will not be an agent of, hold itself out as an agent of,
     or give the appearance of being an agent for Orchid.

12       Maintenance of Quality

12.1 In the course of marketing, promoting,  advertising,  selling and providing
     Genotyping Services under the Orchid Trademarks, DNAPrint will at all times
     maintain and adhere to the quality  standards  adopted by Orchid consistent
     with the high reputation of the Orchid Trademarks.

12.2 Prior to using any Orchid  Trademark  on any type of printed or  electronic
     marketing,  advertising  or  promotional  materials,  DNAPrint  will submit
     samples of the material to Orchid for approval,  which approval will not be
     unreasonably withheld. Once approved by Orchid, DNAPrint may use the Orchid
     Trademarks on printed or electronic  marketing,  advertising or promotional
     materials prepared in accordance with the previously submitted and approved
     samples.

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12.3 To further ensure that quality  standards are maintained,  Orchid will have
     the  right,  but not the  obligation,  to  inspect,  monitor  and  test the
     equipment,   materials  and  procedures,   including  DNAPrint's  SNPstream
     Instrument and Primer Extension method, and to inspect DNAPrint's books and
     records  relating to the  provision of  Genotyping  Services to ensure that
     DNAPrint is in compliance with Orchid's quality  standards.  Any inspection
     will be with  prior  notice  to  DNAPrint  and in a  manner  that  does not
     unreasonably interfere with the business and affairs of DNAPrint.

13       Royalty

13.1 In  consideration  of the  right  and  license  to use  SNP  Assay  Kits in
     performance of Genotyping Services for Permitted Parties, DNAPrint will pay
     to Orchid a royalty equal to fifteen percent (15%) of the total gross sales
     price invoiced for the Genotyping  Services,  less one percent (1%) in lieu
     of any discounts or offsets.

13.2 Notwithstanding  paragraph  13.1,  in no event will the royalty  payable to
     Orchid be less than fifteen percent (15%) of twice  DNAPrint's  actual cost
     (including  overhead) in providing the Genotyping Services as determined in
     accordance with United States generally accepted accounting principles.

13.3 DNAPrint will pay Orchid the royalties accrued in a calendar quarter within
     thirty (30) days after the end of the calendar  quarter and accompany  each
     payment with a report detailing the calculation of the royalties due, which
     report Orchid may rely on without independent verification.

13.4 Where  the  gross  price  for  Genotyping  Services  comprise  non-monetary
     consideration,  in whole  or in part,  DNAPrint  will pay  Orchid  the cash
     equivalent to the fair market value of the non-monetary consideration.

13.5 All  payments  will be made in United  States  Dollars by wire  transfer of
     funds to an account  designated by Orchid or by delivery of an  irrevocable
     cashier's check to Orchid.

13.6 Orchid may add an interest  charge equal to 1/1/2% per month (18% per year)
     on any amounts payable by DNAPrint that remain unpaid after the payment due
     date.
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14       Records and Inspection

14.1 DNAPrint will keep complete and accurate records of all Genotyping Services
     provided,  the cost of providing Genotyping  Services,  the prices invoiced
     for Genotyping  Services,  the names and addresses of third parties to whom
     Genotype  Services  were  provided,  and all other  information  reasonably
     necessary to permit Orchid to verify the quality of the Genotyping Services
     provided and the computation and amount of royalties due Orchid.

14.2 At  Orchid's  request and  expense,  DNAPrint  will  permit an  independent
     certified public accountant  selected by Orchid, and reasonably  acceptable
     to DNAPrint,  to examine all records deemed by the accountant as reasonably
     necessary in  verifying  for Orchid the  computation  of, and the amount of
     royalties  accrued,  payments  made or to be made,  and the accuracy of the
     royalty reports.

14.3 Each  accountant  who  examines  records  will agree in writing to treat as
     confidential  and not to disclose any  information  other than  information
     relating  solely to the  royalties  accrued and the accuracy of the royalty
     reports and payments required to be made.

14.4 The  examination  of  records in all  instances  will be  conducted  during
     reasonable business hours, be limited to once per calendar year, and be for
     a  period  of time of no more  than  three  (3)  fiscal  years  immediately
     preceding the request for examination.

14.5 In the event any examination reveals that DNAPrint under compensated Orchid
     in an amount in excess of five  percent (5%) of the amount  actually  owed,
     DNAPrint  will pay the fees of the account  plus  interest at a rate of one
     and a half  percent  (1 1/2%)  per month  (18% per  year) on the  amount of
     underpayment from the date payment was due to the date payment is made.

15       Warranties

15.1 Orchid warrants that all SNP Assay Kits when delivered to DNAPrint are free
     from defects in materials and workmanship  and conform to their  respective
     Specifications.

15.2 THERE ARE NO OTHER WARRANTIES,  EXPRESS OR IMPLIED,  INCLUDING ANY WARRANTY
     OF  MERCHANTABILITY  OR  FITNESS  FOR A  PARTICULAR  PURPOSE  AND  NONE ARE
     CREATED,  WHETHER UNDER THE UNIFORM COMMERCIAL CODE, CUSTOM OR USAGE IN THE
     INDUSTRY OR THE COURSE OF DEALINGS BETWEEN THE PARTIES.

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15.3 ORCHID MAKES NO WARRANTY OR  REPRESENTATION TO DNAPRINT THAT USE OF ANY SNP
     ASSAY KIT,  FORMATTING,  OR KNOW HOW, OR ANY PRODUCT  PRODUCED BY SUCH USE,
     WILL NOT INFRINGE ANY PATENT, COPYRIGHT, TRADE SECRET, OR OTHER PROPRIETARY
     RIGHT,  FOREIGN OR  DOMESTIC,  OF ANY THIRD  PARTY TO WHICH  ORCHID HAS NOT
     OBTAINED  RIGHTS.  ORCHID  WARRANTS  THAT  IT IS  NOT  AWARE  OF  ANY  SUCH
     INFRINGEMENT AND HAS NOT RECEIVED ANY NOTICE OF POSSIBLE INFRINGEMENT.

15.4 ORCHID DOES NOT WARRANT, GUARANTEE OR MAKE ANY REPRESENTATION REGARDING THE
     USE, OR THE RESULTS OF THE USE,  OR THE  PERFORMANCE  OF THE SNP ASSAY KIT,
     FORMATTING,  OR  KNOW  HOW.  DNAPRINT  REPRESENTS  AND  WARRANTS  THAT  ANY
     STATEMENTS  HERETOFORE  OR  HEREAFTER  MADE  BY  ORCHID  OR ANY  AUTHORIZED
     REPRESENTATIVE  RELATIVE TO THE USE,  RESULTS OF THE USE OR  PERFORMANCE OF
     THE SNP  ASSAY  KIT,  FORMATTING,  OR  KNOW-HOW  WERE  AND WILL  ALWAYS  BE
     INDEPENDENTLY  VERIFIED BY DNAPRINT AND DNAPRINT AGREES THAT ITS ACCEPTANCE
     AND/OR USE OF SUCH STATEMENTS IS ENTIRELY AT ITS OWN RISK.

16       Indemnification

16.1 Orchid agrees to  indemnify,  defend,  and hold harmless  DNAPrint from and
     against all liabilities, damages, expenses and losses (including reasonable
     attorney  fees and  costs),  arising  out of (i) the  negligent  actions of
     Orchid,  its  employees  or any  third  party  acting  on  behalf  or under
     authority  of  Orchid in the  performance  of this  Agreement  and (ii) any
     actual  or  alleged  act  of  patent   infringement,   contributory  patent
     infringement,  inducing  patent  infringement,  or  copyright  infringement
     resulting from DNAPrint's use of the SNP Assay Kits,  Formatting,  Know-How
     or any information and materials received,  in a manner approved by Orchid.
     At any time  during the course of any action  involving a SNP Assay Kit, or
     if in Orchid's opinion a SNP Assay Kit is likely to become the subject of a
     patent  infringement  claim,  Orchid  may at its option  and  expense,  (i)
     procure for  DNAPrint the right to continue  using the SNP Assay Kit,  (ii)
     replace  or modify the SNP Assay Kit so that it  becomes  noninfringing  or
     (iii) accept  return of the SNP Assay Kit,  refund the  purchase  price and
     terminate this Agreement.

16.2 Orchid will not be liable to DNAPrint under paragraph 16.1 if the patent or
     copyright  infringement  claim is based on an alteration or modification of
     the  Formatting,  or  SNP  Assay  Kit or a use of the  SNP  Assay  Kit  not
     authorized by Orchid.

                                       11
<PAGE>

16.3 ORCHID WILL NOT BE LIABLE TO  DNAPRINT  OR ANY THIRD PARTY WITH  RESPECT TO
     ANY USE OF THE SNP ASSAY KIT,  FORMATTING,  OR  KNOW-HOW BY DNAPRINT OR ANY
     AGENT OR EMPLOYEE OF DNAPRINT,  FOR ANY LOSS, CLAIM, DAMAGE OR LIABILITY OF
     ANY KIND OR  NATURE  WHICH MAY ARISE  FROM OR IN  CONNECTION  WITH THE USE,
     HANDLING,  STORAGE OR DISPOSAL OF THE SNP ASSAY KITS,  OR KNOW-HOW,  OR ANY
     PRODUCTS RESULTING FROM SUCH USE; OR ANY CLAIM FOR LOSS OF PROFITS, LOSS OR
     INTERRUPTION OF BUSINESS, OR FOR INDIRECT, SPECIAL OR CONSEQUENTIAL DAMAGES
     OF ANY KIND.

16.4 DNAPrint  agrees to  indemnify,  defend and hold  harmless  Orchid from and
     against all liabilities,  demands,  damages, expenses and losses (including
     reasonable  attorney  fees and costs)  arising out of (i)  DNAPrint's  use,
     handling, storage and disposal of SNP Assay Kits, Formatting,  Know-How and
     any information and materials received from Orchid,  except those resulting
     from  Orchid's  (or  its   employees  or  agents)   negligence  or  willful
     misconduct,  (ii) any products developed or made by DNAPrint as a result of
     the use of the SNP Assay Kits, Formatting, Know-How and any information and
     materials  received from Orchid,  (iii) DNAPrint's  provision of Genotyping
     Services,  and (iv) any  actual  or  alleged  act of  patent  infringement,
     contributory  patent  infringement,   inducing  patent   infringement,   or
     copyright infringement resulting from DNAPrint's use of the SNP Assay Kits,
     Formatting,  Know-How and any  information and materials  received,  in any
     manner not approved by Orchid or in DNAPrint's manufacture,  use or sale of
     any product resulting from such use.

16.5 A party  seeking  indemnification  under this  Agreement  will give  prompt
     written notice to the indemnifying  party of the commencement of any action
     (and any prior  claims  relating to such  action) for which the party seeks
     indemnification.   An   indemnifying   party  will  have  no  liability  or
     responsibility  of any kind to the party seeking  indemnification  if it is
     not promptly notified and does not have adequate opportunity to defend. The
     indemnifying  party will have sole control of the defense of the action and
     of all negotiations for its settlement or compromise.

16.6 This section 16 survives any termination or expiration of this Agreement.

17       Improvements

17.1 Upon, or before,  delivery of  DNAPrint's  initial order of SNP Assay Kits,
     and subject to section 18,  Orchid will  disclose in confidence to DNAPrint
     its Know How regarding the ordered SNP Assay Kits.

                                       12
<PAGE>

17.2 DNAPrint  agrees  to  grant  and  hereby  grants  to  Orchid  a  perpetual,
     world-wide, nonexclusive, royalty-free license to any Improvements directly
     related to the SNP Assay Kits,  Formatting,  and Know How related  thereto.
     This paragraph survives any termination or expiration of this Agreement.

18       Confidentiality

18.1 Orchid agrees not to disclose  publicly or to any third party,  and to keep
     in strictest confidence,  all (i) all information identified by DNAPrint as
     being secret or confidential, and (iii) all information which by its nature
     or the circumstances should be treated as confidential.

18.2 DNAPrint agrees not to disclose publicly or to any third party, and to keep
     in strictest confidence, all (i) prices and price schedules, (ii) Know How,
     (iii) all information identified by Orchid as being secret or confidential,
     and (iv) all information which by its nature or the circumstances should be
     treated as confidential.

18.3 The obligation of  confidentiality  under this section 18 does not apply to
     information  which the recipient can demonstrate is known  publicly,  is in
     the  public  domain or enters the public  domain  without  the fault of the
     recipient,  is  disclosed  to the  recipient  by a third  party  not  under
     obligation of  confidence,  or with respect to Technical  Data was known to
     DNAPrint prior to the Effective Date of this Agreement,  or with respect to
     Assay Data and Know How was known to the recipient  prior to the disclosure
     thereof.

18.4 The  obligations  of this  section 18 survive and  continue for a period of
     five (5) years after any termination or expiration of this Agreement.

19       PUBLICITY

19.1 DNAPRINT  MAY  REFER  TO  ORCHID  AS A  LICENSEE  FOR  THE  PERFORMANCE  OF
     GENOTYPING  SERVICES IN ITS MARKETING  AND  PROMOTIONAL  MATERIALS.  WITHIN
     TWENTY  (20)  DAYS OF THE  EFFECTIVE  DATE OF THIS  AGREEMENT,  ORCHID  AND
     DNAPRINT WILL ISSUE A MUTUALLY ACCEPTABLE JOINT PRESS RELEASE (DESCRIBED IN
     10.1 OF THE "OPTION  AGREEMENT"  IF IN FACT SAID  AGREEMENT  IS  EXECUTED),
     DISCLOSING THE CONFERRAL OF THIS LICENSE.

                                       13
<PAGE>

20       Term and Termination

20.1 Notwithstanding  11.1,  unless  extended by mutual  agreement of Orchid and
     DNAPrint,  this  Agreement  will expire and terminate one year (1) from the
     Effective Date of this Agreement.

20.2 THE TERM OF THE LICENSE TO PROVIDE GENOTYPING SERVICES (11.1) WILL BE FOR A
     PERIOD  OF 5  YEARS,  UNLESS  DNAPRINT  BREACHES  ANY OF THE  TERMS OF THIS
     AGREEMENT, AND WILL BE AUTOMATICALLY RENEWED FOR A SUCCESSIVE 5 YEAR PERIOD
     UNLESS  DNAPRINT  IS  FOUND  TO BE IN  BREACH  OF ANY  PROVISIONS  OF  THIS
     AGREEMENT.

20.3 Orchid and DNAPrint have the right to terminate this Agreement if the other
     fails to make  any  payment  due and  owing,  or  commits  a breach  of any
     material  provision of this Agreement and fails to make such payment within
     thirty  (30)  days or remedy  such  breach  within  sixty  (60) days  after
     receiving written notice of such default or breach.

20.4 Orchid and DNAPrint each have the right to terminate  this Agreement if any
     proceeding  is  instituted  by  or  against  the  other  party  seeking  to
     adjudicate it bankrupt or insolvent,  or seeking  liquidation,  winding up,
     reorganization,  arrangement, adjustment, protection, relief or composition
     of it or its debts under any law  relating  to  bankruptcy,  insolvency  or
     reorganization  or relief of  debtors,  or seeking an entry of an order for
     relief or the appointment of a receiver,  trustee or other similar official
     for it or any  substantial  part of its  property  or taking  any action to
     authorize  any of the  foregoing  or similar  actions.  No assignee for the
     benefit  of  creditors,  receiver,  liquidator,  sequestiator,  trustee  in
     bankruptcy,  sheriff or any other  office of the court or official  charged
     with taking over  custody of  DNAPrint's  assets or business  will have any
     right to continue the performance of this Agreement.

20.5 Upon  expiration or  termination  of this Agreement for any cause or reason
     neither   DNAPrint  nor  Orchid  will  be  released  from  any   obligation
     theretofore accrued.

21       Miscellaneous

21.1 The  relationship  of Orchid and DNAPrint  under this  Agreement is that of
     seller and buyer.  The provisions of this Agreement may not be construed to
     create between Orchid and DNAPrint the relationship of principal and agent,
     joint  venturers,  co-partners  or  any  other  similar  relationship,  the
     existence of which is hereby denied by Orchid and  DNAPrint.  Neither party
     hereto  is  liable in any way for any  engagement,  obligation,  liability,
     contract,  representation  or  warranty  of the other  party to or with any
     third  party.  Orchid is not an agent for  DNAPrint  and DNAPrint is not an
     agent for Orchid for any purpose  whatsoever and each party has no right or
     authority  to assume or create  any  obligations,  express or  implied,  on
     behalf or in the name of the other party.

                                       14
<PAGE>

21.2 No  amendment,  variation,  modification  or  waiver  of any  breach of any
     provision of this Agreement  will be binding unless  executed in writing by
     an authorized  officer of the party to be bound. No waiver of any breach of
     any  provision  of this  Agreement  will  constitute a waiver of any prior,
     concurrent or subsequent  breach of the same or any other provision of this
     Agreement.

21.3 Any notice  required or permitted  under this  Agreement  will be deemed to
     have been  sufficiently  provided and effectively made if sent by facsimile
     and  either  hand-delivered  or sent by  overnight  express  courier  (e.g.
     Federal  Express) and  addressed to the receiving  party at its  respective
     address as follows:

Orchid Biosciences, Inc.                   DNAPrint Genomics, Inc.
303 College Road East                      1748 Independence Boulevard, Suite 1D
Princeton, NJ 08540                        Sarasota, Florida 34234
Facsimile:  (609) 750-2250                 Facsimile:
Attn:  Kevin Nash                          Attn:

With a courtesy copy to:                   With a courtesy copy to:

Kalow & Springut LLP
488 Madison Avenue
New York, NY 10016

Facsimile:  (212) 813-9600                 Facsimile:
Attn:  David A. Kalow                      Attn:

     or such  other  address  of which the  receiving  party  has  given  notice
     pursuant to this paragraph. The effective date of the notice is the date of
     receipt of the hand or courier delivery.

21.4 In the event that the  performance  of this  Agreement or of an  obligation
     hereunder,  other than the payment of money,  is  prevented,  restricted or
     interfered  with by  reason  of any cause not  within  the  control  of the
     respective  party,  and which could not by reasonable  diligence  have been
     avoided by such  party,  the party so  affected,  upon the giving of prompt
     notice to the other party,  as to the nature and probable  duration of such
     event, is excused from such  performance to the extent and for the duration
     of such prevention, restriction or interference, provided that the party so
     affected  uses its  reasonable  efforts  to avoid or remove  such  cause of
     non-performance and continues performance under this Agreement whenever and
     to the extent  such cause or causes are  removed.  For the  purpose of this

                                       15
<PAGE>

     paragraph,  but without limiting the generality  hereof, the following will
     be considered as not being within the control of a party: acts of God; acts
     or omissions of a governmental  agency or body;  compliance  with requests,
     recommendations,   rules,  regulations,   or  orders  of  any  governmental
     authority or any officer, department, agency, or instrument thereof; flood;
     storm; earthquake;  fire; war; insurrection;  riot; accidents;  acts of the
     public enemy;  invasion;  quarantine  restrictions;  strike; labor lockout;
     differences with workmen;  embargoes; delays or failures in transportation;
     and acts of a similar nature.

21.5 If any  provision  of  this  Agreement  is  held  to be  invalid,  illegal,
     unenforceable  or  void,  such  will be  without  effect  on the  validity,
     legality and  enforceability of the remaining  provisions or this Agreement
     as a whole.  Both  parties will  endeavor to replace the invalid,  illegal,
     unenforceable  or void provision with a valid and  enforceable one which in
     its equitable effect is most consistent with the prior provision.

21.6 The paragraph  headings are for convenience only and cannot have any effect
     on the interpretation or construction of this Agreement.

21.7 The laws of the State of New Jersey,  excluding the principles of conflicts
     of laws (and the 1980 U.N.  Convention on Contracts  for the  International
     Sale of Goods),  govern this  Agreement.  Any legal  action  arising from a
     dispute or question  regarding the terms and conditions,  or performance of
     this  contract  may be  instituted  only in the  Superior  Court for Mercer
     County New Jersey or the United States  District  Court for the District of
     New Jersey.  Both DNAPrint and Orchid consent to the personal  jurisdiction
     and waive any  objection to the venue of these  courts.  Both  DNAPrint and
     Orchid  further  consent  that any  service  of  process  may be  served by
     overnight courier or express mail at its address stated in paragraph 20.3.

21.8 The  rights  provided  herein  are  personal  to  DNAPrint  and  may not be
     sub-licensed,  sub-contracted  or otherwise  transferred  without the prior
     express  written  approval of Orchid except in connection  with the sale or
     acquisition of substantially all of the assets or stock of DNAPrint related
     to this Agreement.

21.9 This  Agreement  is binding  upon and  inures to the  benefit of the heirs,
     successors and assigns of the parties hereto, provided that this Agreement,
     in whole or in part,  is not  assignable  by either party without the prior
     written  consent of the other party,  such  consent not to be  unreasonably
     withheld,  except  that Orchid may assign this  Agreement  to an  affiliate
     without  any such  consent.  Any  effort to assign in  violation  hereof is
     considered  void. In the event of any assignment,  the assigning party must
     provide the other party with appropriate documentation of the assignment.

                                       16
<PAGE>

21.10Each party  acknowledges  that it has read this Agreement,  understands it,
     and agrees to be bound by its terms and further  agrees that it constitutes
     the  complete  and  exclusive  understanding  between  the  parties,  which
     supersedes  and merges all prior  proposals,  understandings  and all other
     agreements,  oral and written,  between the parties  regarding  the subject
     matter of this Agreement; and no party has relied on any representation not
     expressly set forth or referred to in this Agreement.

21.11DNAPrint and Orchid  acknowledge that (i) its counsel reviewed the terms of
     this  Agreement,  (ii)  the rule of  construction  to the  effect  that any
     ambiguities are resolved against the drafting party will not be employed in
     the interpretation of this Agreement, and (iii) the terms of this Agreement
     are to be  construed  fairly as to both parties and not in favor or against
     either party,  regardless of which party was generally  responsible for the
     preparation of this Agreement.

21.12This  Agreement may be executed in two or more  counterparts,  all of which
     constitute one and the same legal instrument.

21.13DNAPrint and Orchid agree to execute,  acknowledge, and deliver any further
     instruments  and to do all other acts as may be necessary or appropriate to
     effect the purpose and intent of this Agreement.

IN WITNESS WHEREOF, the parties have executed this Agreement as of the Effective
Date.

DNAPrint Genomics, Inc.                        Orchid Biosciences, Inc.

By:________________________                    By: _______________________

Title:______________________                   Title:_______________________

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