Document:

Investment Agreement by Red Mountain Jet LLC

 Exhibit 4.05 

CONFIDENTIAL TREATMENT REQUESTED. CERTAIN PORTIONS OF THIS 

DOCUMENT HAVE BEEN OMITTED PURSUANT TO A REQUEST FOR 

CONFIDENTIAL TREATMENT AND, WHERE APPLICABLE, HAVE BEEN MARKED 

WITH AN ASTERISK TO DENOTE WHERE OMISSIONS HAVE BEEN MADE. THE 

CONFIDENTIAL MATERIAL HAS BEEN FILED SEPARATELY WITH 

THE SECURITIES AND EXCHANGE COMMISSION. 
  

 
 INVESTMENT
AGREEMENT 
 BY 

RED MOUNTAIN JET LLC, 

AMYRIS BIOTECHNOLOGIES, INC., 

AND 

AMYRIS BRASIL S.A. 

 
  

MAY 26, 2010 
  

 
  

 

 INVESTMENT AGREEMENT 

This Investment Agreement (this “Agreement”) is executed on May 26, 2010
(the “Effective Date”), by the following parties (all of them, collectively, the “Parties” and individually, a “Party”): 

(1)        RED MOUNTAIN JET LLC company
incorporated and existing under the laws of State of Delaware, with head offices at 16192 Coastal Highway, Lewes, Delaware 19958, United States of America, herein represented by its undersigned representatives (“Red Mountain”)

 (2)        AMYRIS BIOTECHNOLOGIES,
INC., a company incorporated and existing under the laws of the State of California, United States of America, with head offices at 5980 Hollis Street, Suite 100, Emeryville, California 94608, Estados Unidos da America herein
represented by its undersigned representatives (“ABI”); and 

(3)        AMYRIS BRASIL S.A., a company incorporated and
existing under the laws of Brazil, with head offices in the city of Campinas, State of Sao Paulo, at Rua James Clerk Maxwell, n° 315, Techno Park, CEP 13069-380, registered with the CNPJ/MF under n° 09.379.224/0001-20, herein represented by
its undersigned representatives (“AB” or the “Company”). 
 WHEREAS: 

(A)        ABI is a technology company focused on the research, development and commercialization
of renewable fuel and renewable chemical products (the “Amyris Renewable Products”) through the use of a proprietary microbial production technology which converts simple sugars derived from various plant sources, including
sugarcane, into specific compounds of interest (the “Amyris Technology”); 

(B)        ABI established operations in Brazil by forming AB in March of 2008 for the purpose of
(i) acquiring an ownership interest in or by any other means partnering with certain sugar and ethanol producers in Brazil and converting a portion of the production capacity of their assets to the production of Amyris Renewable Products, and
(ii) providing other Brazilian sugar and ethanol mills with access to the Amyris Technology for the production of Amyris Renewable Products; 

(C)        To enable AB to carry out these activities, effective as of March 27, 2008, ABI
entered into an intellectual property license with AB (the “Technology License”), the terms of which are attached hereto as Exhibit 1, which provides AB with (i) the exclusive right to use the Amyris Technology to
manufacture Amyris Renewable Products in Brazil and the exclusive right to grant manufacturing sublicenses to mills located in Brazil, (ii) the exclusive right to market and distribute Amyris Renewable Products in Brazil, and (iii) the
non-exclusive right to market and distribute Amyris Renewable Products outside Brazil; 

(D)        On December 22, 2009, Fundo Mútuo de Investimento em Empresas Emergentes
Inovadoras Stratus GC III and Stratus Investimentos Ltda. (both referred to, individually or collectively, as “Stratus”), ABI and AB entered into an Investment Agreement and a Shareholders’ Agreement under which Stratus has
made, to date, an equity investment in AB equal to R$ 10,000,000 (ten million Brazilian Reais) (the “Stratus Cash Contribution”); 

(E)        To date, ABI has made cash contributions to AB in the amount of US$ 10,000,000.00 (ten
million United States dollars) (the “ABI Cash Contributions”); 

 (F)        Red Mountain intends to make a capital
contribution of R$ 10,000,000.00 (ten million Reais) into the Company (“Red Mountain Cash Contribution” and, together with the Stratus Cash Contribution, the “Investors Cash Contribution”); 

Now, therefore, the Parties hereby decide to enter into this Agreement, which shall be governed by the following terms and conditions:

 SECTION ONE 

DEFINITIONS AND INTERPRETATION 

1.1        Definitions. 

“AB” has the meaning set forth in the Preamble. 

“AB Share Price” equals R$ 9.00 (nine Brazilian Reais). 

“ABI” has the meaning set forth in the Preamble. 

“ABI Cash Contributions” has the meaning set forth in item “E” of the preamble hereto. 

“Affiliate” means, with respect to any Person, any other Person that directly, or indirectly through one or more
intermediaries, Controls, or is Controlled by, or is under common Control with, such first Person. 
 “Agreement” has the
meaning set forth in the Preamble and includes all exhibits and schedules hereto. 
 “Amyris Renewable Products” has the
meaning set forth in item “A” of the preamble hereto. 
 “Amyris Technology” has the meaning set forth in item
“A” of the preamble hereto. 
 “Closing” has the meaning set forth in section 3.2.1 hereto. 

“Company” has the meaning set forth in the Preamble. 

“Control” of a company means the power to direct the management and policies of such company and shall be presumed to
exist upon ownership of securities entitling the holder thereof to exercise more than 50% (fifty percent) of the voting power in the election of directors and in the decision of any strategic matter of such company. 

“Definitive Documents” means the Agreement, the Shareholders Agreement and the Minutes of Board of Directors Meeting
mentioned in section 3.1 hereof. 
 “Effective Date” has the meaning set forth in the preamble hereto. 

“Intellectual Property” means all (i) trademarks, service marks, trade names, trade dress, domain names, copyrights
and similar rights, including registrations and applications to register or renew the registration of any of the foregoing, (ii) letters patent, patent applications, inventions, processes, designs, formulae, trade secrets, know-how,
confidential information, computer software, data and documentation, website content, and all similar intellectual property rights, (iii) tangible embodiments of any of the foregoing in any medium, (iv) Information Technology, and
(v) licenses of any of the foregoing. 
 “Investors” shall mean, on the date hereof, Stratus and Red Mountain. 

 “Investors Cash Contribution” has the meaning set forth in item “F” of the
preamble hereto. 
 “Losses” has the meaning set forth in section 7.2 hereto. 

“Party” or “Parties” has the meaning set forth in the Preamble. 

“Person” means any individual, corporation, partnership, limited liability company, firm, joint venture, association,
joint stock company, trust, unincorporated organization, governmental or regulatory body or subdivision thereof, or any other entity. 

“Rules of Arbitration” has the meaning set forth in section 10.2 hereto. 

“Shareholders” means the shareholders of AB, which shall correspond to ABI and the Investors. 

“Shareholders’ Agreement” means the shareholders’ agreement of AB dated December 22, 2009, which shall be
amended on the date hereof as to include Red Mountain. 
 “Shares” shall mean the shares of capital stock of AB. 

“Red Mountain” has the meaning set forth in the Preamble. 

“Red Mountain Cash Contribution” has the meaning set forth in item “F” of the preamble hereto. 

“Stratus” has the meaning set forth in item “D” of the preamble hereto. 

“Stratus Cash Contribution” has the meaning set forth in item “D” of the preamble hereto. 

“Technology License” has the meaning set forth in item “C” of the Preamble hereto. 

“Total Contribution Amount” means that amount equal to (i) the ABI Cash Contribution, plus (ii) the Investors
Cash Contribution. 
 1.2        Interpretation. 

A reference in this Agreement to the singular includes a reference to the plural and vice versa. The term “including” shall be
deemed to be followed by the phrase “but not limited to”. The words “hereof’, “herein”, “hereto”, “hereunder” and similar words refer to this Agreement as a whole. The headings of this Agreement are
included for convenience purposes only and are to be ignored in the interpretation of this Agreement. 
 SECTION TWO

 PURPOSE OF THE COMPANY AND SCOPE OF THIS AGREEMENT 

2.1        Purpose of the Company. 

The Company’s purpose is to (i) acquire an ownership interest in certain or by any other means partnering with certain sugar
and ethanol producers in Brazil and converting a portion of the production capacity of their assets to the production of Amyris Renewable Products, and (ii) provide other Brazilian sugar and ethanol mills with access to the Amyris Technology
for the production of Amyris Renewable Products. 

 2.2        Scope. 

The scope of this Agreement is to establish the terms and conditions of the investments to be made in the Company by Red Mountain.

 2.3        Shareholders’ Agreement. 

Conditions relating to the transfer of the Company’s shares, voting rights, management and public offerings are set forth in the
Shareholders’ Agreement. 
 SECTION THREE 

INVESTMENTS IN THE COMPANY BY RED MOUNTAIN 

3.1        Subscription.  Upon the terms and subject to the conditions of
this Agreement: (a) on May 25th, 2010, AB’s board members shall hold a Board of Directors Meeting of AB and shall resolve on a capital increase in the total amount of R$ 10,000,000.00 (ten million Brazilian Reais), with the issuance
of 1,111,111 (one million, one hundred and eleven thousand, one hundred and eleven) new Shares; (b) on the date hereof, Red Mountain shall subscribe for all of those newly issued Shares, for the total subscription price of R$ 10,000,000.00 (ten
million Brazilian Reais) to be paid within 5 (five) days as from the date hereof; and (c) on the date hereof, AB’s current Shareholders shall waive its preemptive rights for the subscription of the newly issued Shares to be subscribed by
Red Mountain. Each Share shall be worth the AB Share Price. 
 3.2        Closing. 

3.2.1    Timing. 

The closing of issuance and subscription of the Shares as mentioned in Section 3.1 above takes place on the date
hereof, at the offices of Machado, Meyer, Sendacz e Opice Advogados, in the City of São Paulo, State of São Paulo, Brazil (the “Closing”). 

3.2.2    Closing. 

At the Closing: 
  

	 	(a)	 AB shall hold a Board of Directors Meeting and take all of the actions mentioned in section 3.1 above, being the relevant minutes executed by all of
the members of the Board of Directors; 

  

	 	(b)	 AB shall cause 1,111,111 Shares to be issued to Red Mountain, have a subscription bulletin of the newly-issued shares duly prepared and executed by
Red Mountain, and have those shares registered in the name of Red Mountain in the AB’s Share Register Book (Livro de Registro de Ações Nominativas); and 

 

	 	(c)	 The Shareholders’ Agreement shall be amended as to include Red Mountain. 

3.2.3    Deliveries by Red Mountain. 

Subject to the terms and conditions set forth in this Agreement, on the date hereof, Red Mountain shall deliver the
following to AB (the delivery of which may be waived, in writing, by AB): 
  

	 	(a)	 all the Definitive Documents to which Red Mountain is a party and a subscription bulletin duly executed by it; 

	 	(b)	 evidence that Red Mountain has been authorized to execute each of the Definitive Document to which it is a party; and 

 

	 	(c)	 all other documents, instruments, certificates and writings required to be delivered by Red Mountain pursuant to the Definitive Documents.

 3.2.4    Deliveries by AB. 

Subject to the terms and conditions hereof, on the date hereof, AB shall deliver the following to Red Mountain (the
delivery of which may be waived, in writing, by Red Mountain): 
  

	 	(a)	 all the Definitive Documents to which AB is a party duly executed by AB and by the members of its Board of Directors, as the case may be;

  

	 	(b)	 evidence that AB has been authorized to execute each of the Definitive Documents to which they are parties; 

 

	 	(c)	 all other documents, instruments, certificates and writings required to be delivered by AB pursuant to the Definitive Documents.

 3.2.5    Closing Events. 

All of the transactions to occur at the Closing shall be deemed to have occurred simultaneously and neither Party shall
have the obligation to consummate any of the transactions referred to in section 3.1 unless all of such actions shall have been consummated simultaneously. All of the transactions and actions listed in sections 3.2.2, 3.2.3 and 3.2.4 above shall be
deemed to have taken place simultaneously and no action shall be deemed to have been made until all steps taken at the Closing have been completed in form and substance reasonably satisfactory to Red Mountain and AB, and their respective counsels.

 3.2.6    Payment by Red Mountain. 

Red Mountain shall deliver to AB the price of the Shares subscribed by Red Mountain by wire transfers of immediately
available funds, within 5 (five) days as from the date hereof, to the bank account No. [*], held by AB at agency no. [*] of Banco Itaú BBA S.A. Within said period, Red Mountain shall deliver to all other Parties evidence of the wire transfer
of the price of the Shares subscribed by Red Mountain to the referred AB account. 
 SECTION FOUR 

USE OF PROCEEDS 

4.1        Use of Proceeds. 

The Parties agree that the proceeds raised through the ABI Cash Contribution and the Investors Cash Contribution shall be put towards the
funding of projects for production of Amyris Renewable Products in Brazil. 
  

	*	 Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been
requested with respect to the omitted portions. 

 SECTION FIVE 

REPRESENTATIONS AND WARRANTIES 

5.1        General Representations and Warranties. 

Each of the Parties represents and warrants that: 
  

	(i)	 it has been duly incorporated, is validly existing and in good standing under the laws of its place of incorporation; 

 

	(ii)	 it has full power and authority, and has taken all required corporate and other action necessary to execute and deliver this Agreement and to
fulfill its obligations hereunder; the execution, delivery and performance of this Agreement shall not violate any applicable law of its places of incorporation; 

 

	(iii)	 this Agreement constitutes a legal, valid and binding obligation, enforceable against it in accordance with its terms, except (A) as limited by
applicable bankruptcy, insolvency, reorganization, moratorium, fraudulent conveyance, or other laws of general application relating to or affecting the enforcement of creditors’ rights generally or (B) as limited by laws relating to the
availability of specific performance, injunctive relief, or other equitable remedies; 

  

	(iv)	 the execution, delivery and performance of this Agreement do not, and the consummation of the transactions contemplated hereby and compliance with
the terms hereof will not conflict with, or result in any violation of or default under, or give rise to a right of termination, cancellation or acceleration of any obligation, of any contract, corporate or other documents executed by it; and

  

	(v)	 no order, consent, approval or authorization of, or registration, declaration or filing with any governmental authority is required to be obtained
in connection with the execution, delivery and performance of this Agreement or the consummation of the transactions contemplated hereby. 

5.2        Specific Representations and Warranties of AB. 

In addition to the representations and warranties set forth in section 5.1 above, the Company hereby represents and warrants that:

  

	(i)	 AB has all requisite corporate power and authority to own and operate its properties and assets and carry out its business as now conducted;

  

	(ii)	 AB is not a party to any litigation, suit, action, investigation, proceeding, controversy or claim before any governmental authority that could
materially and adversely affect the business; 

  

	(iii)	 AB is not insolvent or unable to pay its debts and has not been held in default by lenders under any debt financing; 

 

	(iv)	 AB has complied with all applicable laws and has not received any written notice nor has any claim alleging failure to comply with any applicable
law and no expenditures are or will be required to comply with any law, except, in any case, in a manner that would not be materially adverse to its business and ability to perform under this Agreement; and 

 

	(v)	 as of the date hereof, the Technology License is in full force and effect and AB is not in violation or default of any term or provision set forth
therein. AB has neither performed any act, the occurrence of which would result in AB’s loss of any right granted under the Technology License, nor failed to perform any act, the failure of which would result in AB’s loss of any right
granted under the Technology License. To the best of AB’s knowledge and belief, after having 

	 	 
carried out any investigation required by law, (A) AB owns or has been granted all necessary Intellectual Property rights to conduct it business as currently conducted, and (B) use of
the Amyris Technology by AB will not infringe the intellectual property rights of any third party. AB has not received any written communications alleging that AB has violated or, by conducting its business as proposed, would violate, infringe or
misappropriate any of the Intellectual Property of any other person or entity. 

 SECTION SIX

 CONFIDENTIALITY. 

6.1        Confidentiality. 

Each of the Parties hereby undertakes to maintain and to procure that its directors, officers, employees, advisers and contractors
maintain in absolute confidentiality, any document or information deemed as confidential by the Parties, including documents, information related to this Agreement and its negotiation process. The provisions of this section shall not apply to any
information: 
  

	(i)	 generally available to the public other than through any disclosure by a Party to the other; 

 

	(ii)	 independently received from a third party who is free from any obligations not to disclose it; 

 

	(iii)	 in the possession of the recipient, on a non-confidential basis, prior to its receipt from the other Party (as demonstrated by contemporaneous
records); 

  

	(iv)	 regarding which the recipient is bound by applicable laws or regulations to disclose, provided that such Party notify the other Party of such
disclosure with a 24 (twenty-four) hour written notice after the requirement by the relevant authority; and 

  

	(v)	 in the case of ABI or AB, information which is provided to actual or prospective investors, underwriters, or acquirers of ABI or AB and/or their
affiliates. 

 SECTION SEVEN 

VALIDITY AND INDEMNITY 

7.1        Validity. 

All representations, warranties and obligations of the Parties set forth in this Agreement shall be valid as from the date hereof and
will remain in full force and effect for the respective statute of limitation. 

7.2        Indemnity. 

Each Party shall indemnify and hold harmless the other Parties and their respective directors, officers, employees, Affiliates,
controlling Persons, agents and representatives and their successors and assigns from and against any liability, demand, claim, action, assessment, expense, damage or loss (“Losses”) arising from (i) the breach of any of its
obligations hereunder and (ii) from the non-compliance with any representation or warranty set forth herein. In addition to the foregoing, AB shall indemnify and hold harmless the other Parties and their respective directors, officers,
employees, Affiliates, controlling Persons, agents and representatives and their successors and assigns from and against any Losses arising 

 
from any illegal act, fact or omission of AB and of any Person who may have served as manager of AB, acting in such capacity within the applicable corporate powers, occurred prior to the Closing.

 The right to indemnification arising from the breach of either Party’s obligation hereunder or from the non-compliance
with any representation and warranty set forth herein will not be affected by any investigation conducted or knowledge acquired at any time, whether before or after the Closing, with respect to the accuracy or inaccuracy of or compliance with, any
such representation, warranty, covenant or obligation. 
 7.2.1    Payments.

  

	 	(a)	 Immediately after having knowledge of any act or fact giving rise to an indemnification under this section 7.2, the applicable Party shall send to
the other Parties hereto a notice to that effect with a description of such act or fact and a copy of any relevant document. 

  

	 	(b)	 If, despite their best efforts, the Parties are not able to reach a mutually acceptable settlement deemed reasonable by all Parties within fifteen
(15) days from the receipt of such notice, the applicable indemnified party shall then have forty-eight (48) hours, counted from the end of the negotiations mentioned herein, to send a notice to the indemnifying party, in which such
indemnified party shall state whether it wishes to start an indemnification claim and, if so, it shall include reasonable details of the nature and basis for such indemnification claim and the total amount related thereto. Upon receipt of such
response notice, the indemnifying party shall have seventy-two hours to either pay or contest the payment of the indemnification claimed by the applicable indemnified party. 

 

	 	(c)	 If (A) the indemnifying party contests and does not make the claimed payment, or (B) the indemnified party contests the payment made by
the indemnifying party of the indemnification claimed, then the indemnified party may start an arbitration procedure against the indemnifying party, in accordance with section 10.2 of this Agreement. The indemnifying party shall be required to pay
any such indemnification within 48 (forty-eight) hours counted as of the date on which a final and non-appealable decision or arbitral award is rendered in favor of the indemnified party with respect to the claim started by the indemnified party
against the indemnifying party or as of the date on which a settlement, agreement or compromise is made with respect thereto. 

  

	 	(d)	 All payments to the applicable indemnified party shall be in immediately available funds and any indemnification payment must be grossed up to cover
any and all taxes payable by the applicable indemnified party on account of such payment. 

  

	 	(e)	 In the event the indemnifying party has knowledge of any act or fact giving rise to an indemnification under this section 7.2 and fails to deliver a
notice in terms set forth herein to the applicable indemnified party, it shall further indemnify the applicable indemnified party for any additional Losses that such a delay may have caused. 

7.2.2    Legal Action or Administrative Proceeding 

 

	 	(a)	 In the event that any legal action or administrative proceeding that could give rise to an indemnification under this section 7.2 is filed against
or made upon any indemnified party, such indemnified party shall notify the indemnifying party, in writing, as soon as reasonably practical, but in no event later than one third (1/3) of the legal term to present

	 	 
a defense for the respective legal action or administrative proceeding. Such notice shall contain, in reasonable detail, a description of the amounts being claimed and the basis thereto.

  

	 	(b)	 The indemnifying party may either decide to present a defense, counterclaim or pay the amount sought under the legal action or administrative
proceeding (including to post a bond for such a defense, if so required), without prejudice to item “f’ below. 

  

	 	(c)	 The indemnifying party shall bear any and all costs incurred, including reasonable attorney’s fees and court fees, guarantees, as well as
expenses incurred in relation to the defense of the legal action or administrative proceeding. In the event the indemnified party receives an order issued by any governmental authority requesting it to make a judicial deposit (or any similar
payment) in connection with such legal or administrative proceeding, then such deposit amount shall be reimbursed by the indemnifying party within 48 (forty-eight) hours as of such payment by the indemnified party. 

 

	 	(d)	 If the indemnifying party assumes the defense of any legal action or administrative proceeding in accordance with the terms of the preceding
sentence, the indemnifying party shall not be entitled to agree to any settlement, agreement or compromise with respect thereto without the prior written consent of the applicable indemnified party, which consent shall not be unreasonably withheld.
The applicable indemnified party shall not be required to agree to any settlement, agreement or compromise that (i) does not contain a full release with respect to the respective legal action or administrative proceeding, or (ii) provides
for any injunctive or other non-monetary relief. 

  

	 	(e)	 In the event that the indemnifying party does not present a defense, counterclaim or pay the amount sought under the legal action or administrative
proceeding and notifies the applicable indemnified party within two thirds (2/3) of the period available for the presentation of the relevant defense, the applicable indemnified party shall have the right to assume the defense of the legal
action or administrative proceeding. The indemnifying party shall promptly and immediately reimburse the applicable indemnified party for any and all expenses incurred in relation to said Legal Action, whether during an administrative or judicial
proceeding, including, but not limited to attorneys’ expenses, court fees, administrative fees and penalties. If the applicable indemnified party assumes the defense of any legal action or administrative proceeding in accordance with the terms
of the preceding sentence, such indemnified party shall be entitled to agree to any settlement, agreement or compromise with respect thereto without the prior written consent of the indemnifying party. 

 

	 	(f)	 Notwithstanding the above, if the indemnifying party believes the legal action or administrative proceeding filed against or made upon any
indemnified party should not give rise to an indemnification under this section 7.2, then the indemnified party may start an arbitration procedure against the indemnifying party, as set forth in section 7.2.1., item “c”, above. In that
case, all costs and expenses incurred by the indemnified party in connection with such legal action or administrative proceeding shall be reimbursed by the indemnifying party after the date on which a final and non-appealable decision or arbitral
award is rendered in favor of the indemnified party, also as set forth in section 7.2.1., item “c”, above. 

 SECTION EIGHT 

TERMINATION 

This Agreement may not be terminated except by the written consent of all the Parties. 

SECTION NINE 

GENERAL PROVISIONS 

9.1        Entire Agreement. 

This Agreement shall constitute the entire agreement between the Parties hereto and supersede and replace all other agreements and
understandings, verbal or written, among the Parties with respect to the subject matter of this Agreement. No amendment or modification of any provision of this Agreement shall be effective unless it is done in writing and signed by each of the
Parties. 
 9.2        Severability. 

The invalidity of one or more provisions of this Agreement shall not affect the validity of this Agreement as a whole unless the invalid
provision was of such essential importance to this Agreement that it is to be reasonably assumed that the Parties would not have entered into this Agreement without such invalid provision. The Parties shall negotiate in good faith to substitute any
invalid provisions with other provisions that may substantially achieve their original intentions. 

9.3        Waiver. 

Any term or condition of this Agreement may be waived at any time by the Party that is entitled to the benefit thereof, but no such
waiver shall be effective unless set forth in a written instrument duly executed by or on behalf of the Party waiving such term or condition. The failure of any Party at any time to enforce any provision of this Agreement shall not in any way affect
its rights to require performance thereof, nor shall the waiver of any breach of any provision hereof be taken or held to be a waiver of any succeeding breach of any such provision or as a waiver or a novation (novação) of the
provision itself. 
 9.4        Assignment. 

No Party may directly or indirectly transfer any of its rights and obligations under this Agreement to any third party, without the prior
written consent of the other Parties. 
 9.5        Costs and Expenses. 

Each Party shall bear all costs and expenses incurred by it in connection with the preparation, negotiation and delivery of this
Agreement. 

 9.6        Notices. 

All notices, requests, claims and other communications hereunder shall be in writing and communicated to the receiving party either by
hand, or sent by registered mail, electronic mail or facsimile and addressed as follows or to such other addresses as may from time to time be notified by any Party to the other Party: 

If to ABI: 
 AMYRIS BIOTECHNOLOGIES,
INC. 
 Address: 5885 Hollis Street, Suite 100, Emeryville, California 94608, USA 

Telephone: +1 510 740-7416 
 Fax: +1 510 842 1460

 E-mail: tompkins@amyris.com 

Attn: Tamara Tompkins - General Counsel 
 If
to Red Mountain: 
 PEDRO PAULO FALLEIROS DOS SANTOS DINIZ 

Address: Rua Jerônimo da Veiga, 384, 3rd floor 

Telephone: +55 11 3705-5161 
 Fax: + 55 11
3702-5112 
 E-mail: pedro@ppdholding.com 

If to AB: 
 AMYRIS BRASIL S.A.

 Address: Rua James Clerk Maxwell, 315, Campinas, SP, Brazil 

Telephone: +55 19 3783-9450 
 Fax: +55 19
3283-0005 
 E-mail: collier@amyris.com 

Attn: Roel Collier 

9.6.1    Delivery of Notice. 

Any notice served by hand shall be deemed to have been served upon delivery. Any notice served by prepaid registered mail
shall be deemed to have been served upon evidenced receipt. Any notice served by e-mail or facsimile shall be deemed to have been served when sent, provided that evidence has been produced showing that the notice has been sent to the facsimile
number/e-mail address, as indicated in this Agreement. 
 9.6.2    Change of Data.

 In case of any change of data, if the new information is not notified by the relevant Party to the other
Party, all notices sent to the previous addresses shall be deemed to have been duly served. 

9.7        Language. 

This Agreement shall be executed in the English and Portuguese languages, provided that the English version shall prevail, including in
arbitration, and excluding when in proceedings before Brazilian courts, in which the Portuguese version shall prevail. 

 SECTION TEN 

GOVERNING LAW AND DISPUTE RESOLUTION 

10.1        Governing Law. 

This Agreement shall be governed by and construed in accordance with the laws of Brazil. 

10.2        Dispute Resolution. 

Any dispute, controversy or claim by and among the Parties to this Agreement, arising out of or relating to this Agreement, or the
breach, termination or validity hereof, shall be settled by arbitration in accordance with the Rules of Arbitration of the Câmara de Comércio Brasil-Canadá (the “Rules of Arbitration”). The decision of the
arbitrators shall be final and binding upon the Parties with no further appeal, recourse or review. Until such decision, the Parties agree to keep the arbitration procedure on a confidential basis, except to the extent necessary for any interim or
conservatory measures permitted under the Rules of Arbitration. 
 10.2.1    Arbitration
Place. 
 The place of arbitration shall be in the City of São Paulo, State of São Paulo,
Brazil, where the arbitration award shall be rendered. 
 10.2.2    Arbitration
Language. 
 The language of the arbitration shall be English. 

10.2.3    Judicial Measures. 

Without prejudice to this section 10.2 and without limiting any other powers the arbitrators may have, the Parties remain
fully entitled to request judicial measures: (a) in order to obtain preliminary and urgent measures (medidas cautelares) prior to the formation of the arbitral tribunal, and such judicial recourse shall not be interpreted as a
waiver of the arbitration as set forth in this section; and (b) to enforce any arbitral decision, including the final award. For that purpose, the Parties elect the courts of the city of São Paulo, State of São Paulo, Brazil,
being waived any other no matter how privileged it may be. The Parties recognize that any provisional or urgent matter granted by judicial courts shall be, necessarily, reviewed by the arbitral tribunal, which shall decide on its ratification,
revision or cancellation. 
 IN WITNESS hereof, this Agreement is executed in 3 (three) counterparts of the same form and
content, in the City of São Paulo, State of São Paulo, Brazil, on May 26, 2010. 
 PARTIES: 

 

	
	
	 /s/ [illegible]

	RED MOUNTAIN JET LLC
	
	/s/ [illegible]
	AMYRIS BIOTECHNOLGOIES, INC.

	
	
	/s/ [illegible]
	AMYRIS BRASIL S.A.

WITNESSES: 
  

					
			
	 1. /s/ Luana Komatsu
	 		 	 2. /s/ Gabriel Aldallah Mundinn

	 Name: /s/ Luana Yo Ko Vieira Komatsu
	 		 	 Name: /s/ Gabriel Aldallah Mundinn

 LIST OF EXHIBITS 
  

	1.	 Technology License 

  

	2.	 Shareholders Agreement 

 EXHIBIT 1 

LICENSE AGREEMENT BETWEEN ABI AND AB 

 LICENSE AGREEMENT 

This LICENSE AGREEMENT (the “Agreement”), effective as of March 27, 2008 (the “Effective
Date”), is made by and between AMYRIS BIOTECHNOLOGIES, INC., a California corporation with a principal place of business at 5885 Hollis St., Ste. 100, Emeryville, CA 94608 (“ABI”), and AMYRIS PESQUISA E
DESENVOLVIMENTO DE BIOCOMBUSTIVEIS LTDA., a company organized and existing as a “sociedade limitada” under the laws of Brazil with headquarters in the city of Campinas, state of São Paulo, at Rua James Clerk Maxwell, n° 315,
Techno Park, CEP 13069-380, registered with the CNPJ/MF under n° 09.379.224/0001-20 (“AB”). ABI and AB are each a “Party” hereto, and collectively are the “Parties.” 

BACKGROUND 

WHEREAS, ABI is a technology company which is focused on the research, development and commercialization of a variety of renewable fuel
and chemical products; 
 WHEREAS, ABI has developed a proprietary microbial production technology which converts sugars derived
from various plant sources, including sugar cane, into renewable fuel and chemical products; 
 WHEREAS, ABI formed AB as a
wholly owned subsidiary with the intent of having AB hold certain rights to such technology in Brazil; 
 WHEREAS, AB intends to
(a) acquire, own and manage sugar cane and ethanol mills in Brazil, and to convert such mills to the production of renewable fuel and chemical products using such technology; and (b) enter into commercial arrangements with other mills hi
Brazil pursuant to which such mills would convert a portion of their assets to the production of renewable fuel and chemical products using such technology; 

WHEREAS, ABI desires to license to AB, the right to use certain ABI technology and the right to use certain ABI trade names and ABI
trademarks (a) on an exclusive basis, to develop, make, have made, use, sell, distribute and market certain renewable fuel and chemical products in Brazil, with the right to grant limited sublicenses to such technology, trade names and
trademarks to mills located in Brazil, and (b) on a nonexclusive basis, to sell, distribute and market certain renewable fuel and chemical products outside of Brazil, in each case under the terms and conditions set forth herein, and AB desires
to obtain such licenses; and 
 WHEREAS, in consideration of the licenses granted herein, AB desires to (a) license back to
ABI the right to use any developments and improvements derived from or related to the ABI technology that. are or become owned or controlled in whole or in part by AB outside of Brazil for any purpose on the terms and conditions set forth herein
(subject only to AB’s nonexclusive license rights), and (b) permit ABI to assist patent prosecution and enforcement matters relating to such developments and improvements, under the terms and conditions set forth herein, and ABI desires to
obtain such a license and such rights: 
 NOW, THEREFORE, on the terms and subject to the conditions set forth herein, the
Parties hereby agree to enter into this Agreement upon the following terms and subject to the following conditions: 

 ARTICLE 1 

DEFINITIONS 
 For
purposes of this Agreement, the following definitions will apply: 

1.1        “ABI Base Technology” means Patents, Production
Strains and Know-How associated with such Patents and Production Strains, in each case that are (a) necessary for the development, manufacture, rise, sale and distribution of Renewable Fuel Products and Renewable Chemical Products Brazil and
(b) Controlled by ABI as of the Effective Date of this Agreement. Patents and Production Strains within the ABI Base Technology are listed on Schedule 1 attached hereto and incorporated herein by reference. 

1.2        “ABI Improvements” means any Patents, Production
Strains and Know-How associated with such Patents and Production Strains comprising Improvements that (a) are necessary for the development, manufacture, use, sale and distribution of Renewable Fuel Products and Renewable Chemical Products in
Brazil and (b) become Controlled by ABI during the Term of this Agreement. Schedule I will be amended by the Parties from rime to time to reflect the inclusion of Patents and Production Strains included within ABI Improvements.

 1.3        “ABI Technology” means the ABI Base
Technology and the ABI Improvements. 
 1.4        “AR
Improvements” means any Improvements and any other Patents, Production Strains or Know-How that are (a) Controlled by any AR Party as of the Effective Date or become Controlled at any time during the Term of this Agreement and for a
period of five years after expiration of the Term of this Agreement, or (b) made, developed or created by or on behalf of any AB Party, or their employees or agents, solely or jointly with any Third Party, during the Term of this Agreement and
for a period of five years after expiration of the Term of this Agreement in each case in connection with the exercise of its rights hereunder or otherwise through use of based upon, derived from or incorporating any ABI Technology. AB Improvements
shall include, without limitation: (i) Improvements to the ABI Technology, (ii) Improvements to Joint Improvements, and (iii) Improvements to other AB Improvements, 

1.5        “AB Parties” means AB, its successors and permitted
assigns and its or their permitted sublicensees. 
 1.6
        “Confidential Information” has the meaning set forth in Section 5.1. 

1.7        “Control” (including any variations such as
“Controlled” or “Controlling”) means, in the context of Patents, Production Strains, Know-How, Improvements and Licensed Marks, rights to such Patents, Production Strains, Know-How, improvements and Licensed Marks sufficient to
grant the applicable license or assignment under this Agreement without violating the terms of any arrangement with any Third Party. 

1.8        “Improvements” means all enhancements, modifications
and revisions, whether or not protectable under intellectual property laws, based upon, derived from or incorporating any ABI Technology or other applicable technology in which ABI holds any right, title or interest. 

1.9        “Joint Improvements” means any Patents, Production
Strains or Know-How that are made, developed or created-jointly by or out behalf of ABI and by or on behalf or any AB Party, or their employees or agents, during the Term of this Agreement and for a period of five years after expiration of the Term
of this Agreement. 

1.10        “Know-How” means non patented information and
tangible materials, including: (a) technical and non-technical data, specifications, formulae, compounds, formulations, assays, designs, results, information, conclusions, interpretations, inventions, developments, discoveries, ideas,
improvements, and trade secrets; (b) methods, databases, tests, procedures, processes and techniques; (c) biological material, including strains, progeny, clones, vectors, recombinant DNA and samples; and (d) other know-how and
technology. 
 1.11        “Licenses” has the meaning
set forth in Section 2,1. 
 1.12        “Licensed
Marks” means, collectively, (a) the trade name “Amyris”; (b) the logo set forth on Schedule 2, attached hereto and incorporated herein by reference; (c) the additional trademarks listed on Schedule 3,
attached hereto and incorporated herein by reference; and (d) such future marks as determined by ABI in its sole discretion from time to time ns appropriate for the development, manufacture, use, sale or distribution of Renewable Fuel
Products and Renewable Chemical Products in Brazil. Schedule 3 and Schedule 4 (Requirements of Licensed Marks Use), attached hereto and incorporated herein by reference will be amended by the Parties from time to time to reflect the inclusion
of such future marks and appropriate requirements for lie use of such marks. 

1.13        “Patents” means any patents and patent applications,
together with all additions, divisions, continuations, continuations-in-part, substitutions, reissues, re-examinations, extensions, registrations, patent term extensions, supplemental protection certificates, renewals, and the like with respect to
any of the foregoing. 
 1.14        “Production
Strain” means recombinant yeast that has been genetically engineered by or on behalf of ABI (which shall be deemed to include any Production Strains made by AB on behalf of ABI1) to make a five carbon (CS), ten carbon (C10), or a fifteen
carbon (C15) isoprenoid product during fermentation. 

1.15        “Term” has the meaning set forth in
Section 9.1. 
 1.16        “Third Party” means
any person, corporation, joint venture or other entity, other than ABI or AB or their respective permitted successors and assigns. 

1.17        “Renewable Chemical Products” means a compound made
directly by a Production Strain for use in industrial operations or in the commodity chemicals industry as a raw material which is then converted to a product of interest by formulation or by a chemical change in the compound. The term excludes use
of a compound made directly by a Production Strain, including derivatives thereof, for use in pharmaceutical formulations, drugs and as ingredients in food. 

1.18        “Renewable Fuel Products” means a combustible
material that (a) is used to generate energy (heat or power), and (b) is derived from a product made by a Production Strain, 

 ARTICLE 2 

TECHNOLOGY LICENSES 

2.1        ABI Technology License Grant. 

 

	 	(a)	 Grant. Subject to the terms and conditions of this Agreement, ABI hereby grants to AB (i) an exclusive royalty-free right to the ABI
Technology to develop, make, have made, use, sell, distribute and market Renewable Fuel Products and Renewable Chemical Products in Brazil; and (ii) a non-exclusive royalty-free right to the ABI Technology to sell, distribute and market
Renewable Fuel Products and Renewable Chemical Products outside of Brazil. The foregoing grant is achieved by a grant of multiple licenses on a Patent-by-Patent and a Production Strain-by-Production Strain basis (collectively, the
“Licenses”), whereas each such License includes the Know-How associated with the Patent or Production Strain covered by such License. The foregoing Licenses include the right to grant limited sublicenses accordance with
Section 2.2. 

  

	 	(b)	 Term. The term of each License will be determined un a License-by-License basis as follows: (i) each License to a Patent will expire
upon the expiration of the term of the applicable Patent, unless earlier terminated as permitted herein; and (ii) each License to a Production Strain will expire upon the expiration of the applicable Patent, if any, covering such Production
Strain or, if there is no Patent covering such Production Strain, then upon expiration of the last License to a Patent hereunder. 

2.2        Sublicense Rights to ABI Technology.  AB may grant limited
sublicenses under the Licenses granted under Section 2.1 to sugar cane and ethanol mills in Brazil that are being Converted either by AB in its capacity as a shareholder in such mills, or by the mill itself pursuant to a commercial agreement
with AB, to the production of Renewable Fuel Products and Renewable Chemical Products in Brazil. Each sublicense will be in a form approved in advance by ABI, as determined by ABI in its sole discretion and may be granted only under the following
terms and conditions unless otherwise agreed to by ABI in writing in its sole and absolute discretion: 
  

	 	(a)	 Each such sublicense will only permit the sublicensee to develop, make and have made Renewable Fuel Products and Renewable Chemical Products in
Brazil (or for that subset of uses and for such subset of Renewable Fuel Products and Renewable Chemical Products that ore determined by AB in such sublicense.) 

 

	 	(b)	 Each such sublicense will not conflict with, and will be expressly subordinate to, the terms and conditions of this Agreement. In the event of a
conflict, the terms of this Agreement shall prevail. 

  

	 	(c)	 Each such sublicense will prohibit the sublicensee from further sublicensing. 

 

	 	(d)	 AB will remain responsible to ABI under each sublicense for all the obligations of AB under this Agreement. 

 

	 	(e)	 Upon the expiration or earlier termination of this Agreement, at the option of ABI, all sublicenses granted hereunder will either continue with ABI
succeeding AB as licensor, or automatically terminate, as determined by ABI in its sole discretion. 

	 	(f)	 Promptly following the execution of each sublicense, AB will provide ABI with an executed copy of such sublicense agreement.

 For the avoidance of doubt, if AB desires to transfer any ABI Technology, including without limitation any
Production Strain or any other tangible biological material received from ABI or derived from any materials received front ABI, to any Third Party to pursue development or scale-up work consistent with the license rights granted hereunder, such
transfer must also be documented on the terms required for sublicenses set forth above. 

2.3        AB License Grant Back to AB Improvements.  AB hereby grants to ABI an
exclusive fully paid-up, perpetual, irrevocable, royalty-free right and license, including the right to grant sublicenses in ABI’s sole and absolute discretion, to use the AB Improvements on an exclusive basis (subject only to AB’s
nonexclusive license rights granted by ABI hereunder) to develop, make, have made, use, sell, have sold, distribute, have distributed and market Renewable Fuel Products and Renewable Chemical Products and any other purpose whatsoever worldwide,
excluding Brazil. AB will not grant rights to any Third Party to AB Improvements inconsistent with this Agreement. 

2.4        AB License Grant Back to AB Interest in Joint Improvements.  AB
hereby grants to ABI an exclusive (even as to AB) fully paid-up, perpetual, irrevocable, royalty-free right and license, including the right to grant sublicenses in ABI’s sole and absolute discretion, to use AB’s interest in the Joint
Improvements (subject only to AB’s nonexclusive license rights granted by ABI hereunder) (a) worldwide, excluding Brazil, to develop, make, have made, use, sell, have sold, distribute, have distributed and market Renewable Fuel Products
and Renewable Chemical Products and for any other purpose, whatsoever and (b) in Brazil, for any purpose other than developing, making, having made, using, selling, having sold, distributing, having distributed and marketing Renewable Fuel
Products and Renewable Chemical Products. AB will not grant rights to any Third Party to AB’s interest in the Joint Improvements inconsistent with this Agreement. For the avoidance of doubt, the Parties hereby affirm that they (i) intend
for the foregoing provisions to mean that AB shall grant back to ABI the rights AB otherwise have to use AB’s interest in the Joint Improvements for the purposes described in clauses (a) and (b; (ii) agreed to such rights after due
diligence, careful deliberation and consultation with counsel; and (iii) agree that neither Party shall require the permission of the other Party to use the rights granted to such other Party in this Section 2.4 notwithstanding that the
law of jurisdictions other than the State of California, United States of America might otherwise grant such other Party pre-approval, prior consent or other similar blocking or permission rights. 

2.5        No Other Rights.  Except as expressly granted herein, no right, title
or interest is granted by ABI to AB. In addition, any license granted by ABI under this Agreement is subject to applicable laws and regulations, including United States laws and regulations as shall front time to time govern the license and delivery
of technology and products between the United States and other countries, including the United States Foreign Assets Control Regulations, Transaction Control Regulations and Export Control Regulations, as amended, and any successor legislation
issued by the Department of Commerce, International Trade Administration, Office of Export Licensing, which laws and regulations may restrict ABI’s ability to grant the lice-use or deliver the ABI Technology. In the event any such restrictions
are found to apply, the Parties will work together in good faith to comply with requirements to lift or otherwise satisfy such restrictions. The costs of any activities in connection therewith will be borne by AB. 

 ARTICLE 3 

TRADEMARK LICENSE GRANTS 

3.1        Grant of Trademark License.  Subject to the terms and conditions of
this Agreement, ABI hereby grants to AB an exclusive license, without the right to sublicense, to use the Licensed Marks in Brazil to practice the ABI Technology to develop, make, have made, use, sell, distribute and market Renewable Fuel Products
and Renewable Chemical Products in Brazil. The term of such license will expire, unless earlier terminated as permitted herein, upon the earlier of (a) fifteen (15) years from the Effective Date, and (b) the expiration of all of the
Licenses granted in Section 2.1, 
 3.2        Acknowledgment of
Rights.  ABI acknowledges that ABI is the owner of the Licensed Marks, and that all use of the Licensed Marks by AB inures to the benefit of ABI. AB further acknowledges that the Licensed Marks embody substantial goodwill and enjoy
favorable public recognition, and that ABI’s rights therein constitute valuable assets of ABI. 

3.3        Quality Control.  In order to protect the goodwill and reputation
associated with the Licensed Marks, AB agrees that AB will provide ABI with representative specimens of advertising and promotional materials showing AB’s use of the Licensed Marks and will use the Licensed Marks in publicly disseminated
materials in the manner set forth in the requirements of Requirements of Licensed Marks Use set forth on Schedule 4 attached hereto. Any deviation from the Requirements of Licensed Marks Use must be approved by ABI in writing. 

3.4        Trademark Maintenance.  During the Term of this Agreement, ABI, at
its own cost, will be responsible for maintaining and renewing registrations for the Licensed Marks. AB will cooperate with ABI in its efforts to protect the Licensed Marks in Brazil, including exerting its best efforts to exploit the Licensed Marks
so as to maintain their validity in the territory of Brazil. ABI will timely notify AB of its decision not to maintain registration for any of the Licensed Marks in Brazil. If registration of AB as a registered user of the Licensed Marks is
required, AB will bear all expenses, including government fees and attorney and trademark agent lees, relating to such registration. 

3.5        Licensed Mark Infringement. 

 

	 	(a)	 Enforcement of Licensed Marks.  If either Party becomes aware of any use by any Third Party of any name, mark or designation that
infringes or is likely to infringe any of the Licensed Marks in Brazil, that Party will notify the other Party promptly in writing of the actual or threatened infringement. Whether to take action will be in ABI’s sole discretion. If requested
by ABI, AB will join with ABI at ABE’s expense in such action as ABI in its reasonable discretion nay deem advisable for the protection of its rights. In connection therewith, AB will cooperate to the extent reasonably required by ABI to stop
such infringement or act, and, if so requested by ABI, will join with AB as a party to any action brought by ABI for such purpose. ABI will have full control over any action taken, including, without limitation, the right to select counsel, to
settle on any terms it deems advisable in its discretion, to appeal any adverse decision rendered in any court, to discontinue any action taken by it, and otherwise to make any decision in respect thereto as it in its discretion deems advisable. Any
recovery as a result of such action shall belong solely to ABI. 

  

	 	(b)	 Infringement of Third Party Marks.  If AB receives any written notice or claim that the use by AB of the Licensed Marks infringes
the intellectual property rights of a Third Party, then AB will promptly so notify ABI in writing. ABI shall have the right, but not 

	 	 
the obligation, to defend against any such claim. If requested by ABI, AB will join with ABE at ABI’s expense in such action as ABI in its reasonable discretion may deem advisable for the
protection of its rights. In connection therewith, AB will cooperate to the extent reasonably required by ABI, and, if so requested by ABI, will join with ABI as a party to any action brought by ABI for such purpose. ABI will have full control over
any action taken, including; without limitation, the right to select counsel, to settle on any terms it deems advisable in its discretion, to appeal any adverse decision rendered in any court, to discontinue any action taken by it, and otherwise to
make any decision in respect thereto as it in its discretion deems advisable, 

 ARTICLE 4 

DILIGENCE; REPORTING 

4.1        Diligence.  AB will use commercially reasonable efforts, consistent
with prudent and reasonable business practices and judgment, to develop, make, and have made, directly or through its permitted sublicensees, and to use, sell, distribute and market Renewable Fuel Products and Renewable Chemical Products in Brazil.
AB shall permit auditors or inspectors appointed by ABI to have access during ordinary business hours and as may be necessary, to monitor compliance of AB with this Agreement. 

4.2        AB Reporting.  During the Term of this Agreement, AB will keep ABI
informed as to the activities of AB and its sublicensees with respect to the development, manufacture, use, sale or distribution of Renewable Fuel Products and Renewable Chemical Products or otherwise involving the ABI Technology. In connection
therewith, AB will deliver to ABI, and will cause its sublicensees to deliver to ABI, no less frequently than quarterly, a written report summarizing in reasonable detail progress with respect to such activities since the last such report, including
without limitation any AB Improvements and Joint Improvements which have arisen during such time period. 

4.3        ABI Reporting.  During the Term of this Agreement, ABI will keep AB
informed annually as to any ABI Technology or marks, trade names or trademarks that have become subject to any license under this Agreement. 

ARTICLE 5 

CONFIDENTIALITY 

5.1        Confidential Information.  The Parties understand and agree that in
the performance of this Agreement each party may have access to proprietary or confidential data or information of the other Party, including, but not limited to, trade secrets, intellectual property, services and/or the business, finances, or
affairs of either Party (“Confidential Information”). Confidential Information may be communicated orally, visually, in writing or in ally other recorded or tangible form. All data and information shall be considered to be
Confidential Information hereunder (i) if either Party has marked them as such, (ii) if either Party, orally (to be reduced to writing) or in writing, has advised the other Party of their confidential nature, or (iii) if, due to
their-character or nature, a reasonable person in a like position and under like circumstances would treat them as confidential. 

5.2         Disclosure of Confidential Information.  Each Party will maintain in
confidence and not disclose to any third party any Confidential Information of the other Party. Each Party will use the Confidential Information of the other Party only for the purposes of this Agreement. Each Party will ensure that access to
Confidential Information will be provided to its employees and officers only on a need to know basis if such employees and/or officers must be familiar with the same in connection with the performance of

 
their duties. Such employees and officers must be informed that the Confidential Information may be used only as permitted under this Agreement and must be obligated in writing to abide by such
Party’s obligations under this Agreement. The receiving party shall immediately notify the disclosing party of any unauthorized disclosure or use of any Confidential Information by the disclosing party that comes to receiving party’s
attention and shall take all action that the disclosing party reasonably requests to prevent any timber unauthorized use or disclosure thereof. AB will cause each and every officer and employee and worker of AB who is likely to acquire knowledge of
any Confidential Information of ABI to keep the confidentiality of such Confidential Information and agrees to prepare a written statement of undertaking agreeing that it will comply with the provisions of this Article 5. 

5.3        Exceptions.  The provisions of this Article 5 will not apply, or will
cease to apply, to Confidential Information supplied by the disclosing party if disclosing party demonstrates by written evidence that (i) was in the receiving party’s possession without restriction on use or disclosure prior to receipt
from the disclosing Party as shown by files existing at the time of disclosure, (ii) has come into the public domain other than through a breach of confidentiality by the receiving party, (iii) was developed independently by employees of
the receiving party or by persons who have not had access to the disclosing party’s Confidential Information; (iv) was or is lawfully obtained, directly or indirectly, by the receiving party from a third party under no obligation of
confidentiality, or (v) is required to be disclosed pursuant to any statutory or regulatory provision or court order; provided, however, that the receiving party provides notice thereof to the disclosing party, together with the statutory or
regulatory provision, or court order, on which such disclosure is based, as soon as practicable prior to such disclosure so that the disclosing party has the opportunity to obtain a protective order or take other protective measures as it may deem
necessary with respect to such information. 

5.4        Survival.  The obligations of the Parties under this Article 5 shall
remain in effect for five (5) years from the dale of termination or expiration of this Agreement. 
 ARTICLE 6

 INTELLECTUAL PROPERTY; PATENT PROSECUTION AND MAINTENANCE 

6.1        Ownership of Patents and Know-How. 

 

	 	(a)	 ABI Technology.  As between the Parties, ABI will own all right, title and interest in and to the ABI Base Technology and the ABI
Improvements, subject only to the licenses set forth herein. 

  

	 	(b)	 AB Improvements.  As between the Parties, AB will own all right, title and interest in and to the AB Improvements, subject only to
the licenses set forth herein and the rights conferred in Section 6.2. 

  

	 	(c)	 Joint Improvements.  The Parties will jointly own own all right, title and interest in and to the Joint Improvements, subject only
to the licenses set forth herein and the rights conferred in Section 6.2. 

6.2        Patent Strategy and Prosecution. ABI shall have the sole right to
(i) determine the process for protecting The ABI Technology, the Joint Improvements and the AB Improvements worldwide, including whether or not to obtain patent protection and in what countries, and (ii) at its own expense, but without
obligation, to prepare, file, prosecute and maintain throughout the world any and all Patents claiming or relating to the ABI Technology, the Joint Improvements and the AB Improvements. For the avoidance of doubt, the Parties hereby affirm that they
intend for the foregoing provisions to apply and be upheld as an 

 
agreement reached between the Parties after due diligence, careful deliberation and consultation with counsel, notwithstanding that the law of jurisdictions other than the State of California,
United States of America might otherwise not permit, uphold or otherwise enforce the granting of such rights. 

6.3        Cooperation and Assistance.  AB will provide to ABI and/or its
designee. and AB will cause any and all relevant AB Parties to provide to ABI, as reasonably requested by ABI and at ABI’s expense (including reasonable attorney’s fees and other reasonable legal expenses), full cooperation and assistance
(including the execution and delivery of any and all affidavits, declarations, oaths, exhibits, assignments, powers of attorney, or other documentation as may be reasonably required): (i) in order to allow ABI to apply for, register, obtain,
maintain, defend, and enforce the Patents for which ABI has control under Section 6.2 and/or its rights therein: (ii) in connection with the prosecution or defense of any interference, opposition, re-examination. reissue, infringement,
declaratory judgment, or other judicial or legal administrative proceedings that may arise in connection with such Patents (including the validity and/or enforceability thereof) and/or any Production Strains, Know-How or other intellectual property
owned by ABI (including testifying as to any facts, production of any documents, responses to any requests or demands relating to such Patents, Production Strains and/or Know-How); and/or (iii) in order to perfect the delivery, assignment, and
conveyance to ABI, its successors, assigns, and nominees, of the entire right, title, and interest in and to all ABE Technology. 

6.4        Enforcement of Patents.  In the event either Party becomes aware of
any activity that infringes or is likely to infringe the ABI Technology, the AB Improvements or the Joint Improvements, that Party will notify the other Party promptly in writing of the actual or threatened infringement. Whether to take action will
be in ABI’s sole discretion whenever the infringement involves ABI’s rights. If requested by ABI, AB will join with ABI at ABI’s expense in such action as ABI in its reasonable discretion may deem advisable for the protection of its
rights. In connection therewith, AB will cooperate to the extent reasonably required by ABI to stop such infringement or act, and, if so requested by ABI, will join with ABI as a party to any action brought by ABI for such purpose. ABI will have
full control over any action taken, including, without limitation, the right to select counsel, to settle on any terms it deems advisable in its discretion, to appeal any adverse decision rendered in any court, to discontinue any action taken by it,
and otherwise to make any decision in respect thereto as it in its discretion deems advisable. Any recovery as a result of such action shall belong solely to ABI. 

6.5        Infringement of Third Party Rights.  In the event either Party
receives any written notice or claim that the use of the ABI Technology, the AB Improvements or the Joint Improvements infringes or is likely to infringe the intellectual property rights of a Third Party, then that Party will notify the other Party
promptly in writing. Whether to take action to defend against any such claim will be in ABI’s sole discretion. If requested by ABI, AB will join with ABI at ABI’s expense in such action as ABI in its reasonable discretion may deem
advisable for the protection of its rights. In connection therewith, AB will cooperate to the extent reasonably required by ABI. and, if so requested by ABI, will join with ABI as a party to any action brought by ABI for such purpose. ABI will have
full control over any action taken, including, without limitation, the right to select counsel, to settle on any terms it deems advisable in its discretion, to appeal any adverse decision rendered in any court, no discontinue any action taken by it,
and otherwise to make any decision in respect thereto as it in its discretion deems advisable. For the avoidance of doubt, the Parties hereby affirm that they intend for the foregoing provisions to apply and be upheld as an agreement reached between
the Parties after due diligence, careful deliberation and consultation with counsel, notwithstanding that the law of jurisdictions other than the State of California, United States of America might otherwise not permit, uphold or otherwise enforce
the granting of such rights. 

 ARTICLE 7 

REPRESENTATIONS AND WARRANTIES 

ABI hereby represents and warrants to AB and AB hereby represents and warrants to ABI that as of the Effective Date:

  

	 	(a)	 They have the full right, power and authority to enter into this Agreement, this Agreement has been duly executed by such Party and constitutes a
legal, valid and binding obligation of such Party, enforceable in accordance with its terms; 

  

	 	(b)	 The execution, delivery and performance of this Agreement does not conflict with, or constitute a breach or default under any of its charter or
organizational documents, any law, order or judgment or governmental rule or regulation applicable to it, or any material agreement, contract commitment or instrument to which it is a party; and 

 

	 	(c)	 They shall comply in all material respects with all applicable laws, rules, regulations and other governmental requirements relating to or affecting
its performance under this Agreement, and shall obtain and maintain all governmental permits, licenses and consents required in connection therewith. 

ARTICLE 8 

INDEMNIFICATION; INSURANCE 

8.1        Indemnification.  AB agrees to defend, indemnify and hold harmless
ABI and its directors, officers, shareholders, employees, and agents (collectively, the “ABI Indemnitees”) from and against any and all suits, claims, actions, or demands (“Claims”), and any liabilities, damages,
costs, expenses and/or losses incurred, including reasonable legal expenses and attorneys’ lees (collectively, “Losses”), suffered or sustained by any ABI Indemnitee, or to which an ABI Indemnitee becomes subject, arising out
of or attributable to any of the following: (a) a breach by AB or a AB Party or its or their respective directors, officers, employees, agents, successors, assigns or sublicensees of a representation, warranty, covenant or agreement made or
undertaken by AB under this Agreement; (b) the practice of any license granted by ABI to AB pursuant to this Agreement or any other use of the ABI Technology, the Joint Improvements, the Licensed Marks or ABI’s Confidential Information by
AB or a AB Party or its or their respective director’s, officers, employees, agents, successors, assigns or sublicensees; or (c) the negligence, recklessness or willful misconduct of AB or a AB Party or its or their respective directors,
officers, employees, agents, successors, assigns or sublicensees. ABI and any ABI indemnitee may, at its option and expense, be represented by counsel of its choice in any action or proceeding with respect to any such Claim or Loss. ABI will not
settle any Claim or Loss if such settlement: (i) does not fully and unconditionally release the ABI Indemnitees from all liability relating thereto; or (ii) adversely impacts the rights granted to any ABI Indemnitee under this Agreement,
unless each affected ABI Indemnitee otherwise agrees in writing. 

8.2        Insurance.  At any time, promptly upon ABI’s request, AB will
obtain and maintain, at its sole cost and expense, comprehensive general liability insurance providing reasonable coverage in respect of AB’s activities under this Agreement and in its practice of the licenses granted hereunder. AB will provide
ABI with written evidence of such insurance upon ABI’s request. 

 ARTICLE 9 

TERM AND TERMINATION 

9.1        Term.  This Agreement will commence on the Effective Date and, unless
earlier terminated as permitted herein, will continue until the expiration of all of the Licenses granted in Section 2.1 (the “Term”). 

9.2        Termination by AB.  AB may terminate this Agreement at any time upon sixty
(60) days written notice to ABI. 
 9.3        Termination by
ABI.  The failure by AB comply with any of the material obligations contained in this Agreement shall entitle ABI to give notice to have the default cured. If such default is not cured within sixty (60) days, or diligent steps are
not taken to cure if by its nature such default could not be cured within sixty (60) days, ABI shall be entitled, without prejudice to any of its other rights conferred on it by this Agreement, and in addition to any other remedies that may be
available to it, to terminate this Agreement. In addition, ABI may terminate this Agreement upon ABI’s written notice to AB in the event that (a) such termination is necessary to comply with any order, decree or request of the government
of either Party hereto or of any court department or agency thereof; (b) normal conduct of the business of AB as a private enterprise ceases or is substantially altered as a consequence of any action taken by governmental, judicial, or any
other authority: or (c) AB makes a general assignment for the benefit of creditors, is the subject of proceedings in voluntary or involuntary bankruptcy instituted on behalf of or against AB, or has a receiver or trustee appointed for all or
substantially all of its property. 
 9.4        Effect of Expiration and
Termination.  Upon the expiration or termination of this Agreement for any reason: (a) all licenses under this Agreement immediately terminate, except that, at the option of ABI, all sublicenses granted hereunder may continue as
determined by ABI in its sole discretion; (b) AB and its sublicensees will cease using the ABI Technology for any and all purposes (except for uses under sublicenses continued as determined by ABI in its sole discretion); (c) within thirty
(30) days of termination, AB will return or destroy, at its own expense, all tangible Know-How provided by, or owned by, ABI to ABI in accordance with written instructions from ABI; and (d) each Party will return, at its own expense, to
the other Party all Confidential information of the other Party within thirty (30) days of termination. 

9.5        Survival of Obligations.  The termination or expiration of this
Agreement shall not relieve the Parties of any obligations accruing prior to such termination, and any such termination shall be without prejudice to the rights of either Party against the other. The provisions of Sections 2.2, 2.3, 2.4, 2.5, 3.5,
8.1, 9.4 and 9.5 and Articles 5, 6, 7 and 10 shall survive any termination of this Agreement. 
 ARTICLE 10 

MISCELLANEOUS 

10.1        Governing Law; Venue.  This Agreement shall be governed by, and
construed in accordance with the laws of the State of California, United States of America, as if entered into by California residents and executed and wholly performed within the State of California. Any dispute as to the performance, enforcement,
validity, or interpretation of this Agreement shall be brought only in a federal court of competent jurisdiction (or a state court if no federal court has jurisdiction) located in the Northern District of California, and the Parties hereby submit to
the exclusive jurisdiction and venue of such courts. For the avoidance of doubt, the Parties hereby affirm that they intend for the laws of the Slate of California to apply to the interpretation and enforcement of this Agreement as a whole as well
as each provision set 

 
forth herein, including, without limitation; all matters set forth in the Recitals, Article 2 and Article 6. The Parties’ decision to designate the laws of the State of California as the
governing law of this Agreement was reached after due diligence, careful deliberation and consultation with counsel and the Parties intend for this to be upheld and enforced notwithstanding that certain activities and obligations under this
Agreement shall be performed outside the State of California and/or outside the United Stales of America. 

10.2        Entire Agreement.  This Agreement (including all Schedules attached
hereto) contains the entire agreement between the Parties with respect to the subject matter hereof and supersedes any and all prior and contemporaneous, express and implied, agreements, understandings, and representations, either written or oral,
which may have related to the subject matter hereof in any way. 

10.3        Assignment.  This Agreement may not be assigned or otherwise
transferred, nor, except as otherwise expressly provided in this Agreement, may any right or obligation tinder’ this Agreement be assigned or otherwise transferred, by AB, including without limitation any assignment or transfer in connection
with a change of control or otherwise by operation of law, without the consent of ABI. Any permitted assignee shall assume all obligations of AB under this Agreement. Any purported assignment by AB in violation of this Agreement shall be void. This
Agreement shall he binding upon, and inure to the benefit of, each Party, its successors and permitted assigns. 

10.4        Waiver; Amendment.  Except as otherwise expressly provided in this
Agreement, any term of this Agreement may be waived only by a written instrument executed by a duly authorized representative of the Party waiving compliance. The delay or failure of any Party at any time to require performance of any provision of
this Agreement shall in no manner affect such Party’s rights at a later time to enforce the same. No alteration, amendment, change, or addition to this Agreement will be binding upon the Patties unless reduced to writing and signed by an
authorized officer of each Party. 
 10.5        Notices.  Any notice
or other communication required or permitted to be given under this Agreement must be in writing, in the English language, must specifically refer to this Agreement, and will be deemed given on the date delivered to the receiving Party if and when
(a) delivered personally with a signed receipt of personal delivery; (b) sent by facsimile (receipt electronically verified and a copy promptly sent by personal delivery, registered or certified mail or courier as provided herein);
(c) sent by internationally recognized courier providing evidence of receipt; or (d) sent by registered or certified mail, postage prepaid, return receipt requested. All such notices will be addressed to the Parties as follows (or such
other address or facsimile number for a Party as may be specified by like notice): 
  

	 	For ABI:	 Amyris Biotechnologies, Inc. 

	 	    	 5885 Hollis St,, Ste, 100 

	 	    	 Emeryville, CA 94608 

	 	    	 Fax: (510) 740-7416 

	 	    	 Attn: General Counsel 

	 	

	 	For AB:	 Amyris do Brasil Pesquisa e Desenvolvimento de 

	 	    	 Biocombustiveis Ltda. 

	 	    	 Rua James Clerk Maxwell,
no 315 

	 	    	 Techno Park, Campinas 

	 	    	 Sâo Paulo, Brazil 

	 	    	 Fax: 55 19 3283 0005 

	 	    	 Attn: Roel Collier 

 10.6        No Strict
Construction.  This Agreement has been prepared jointly and will not be strictly construed against either Party. 

10.7        Severability.  If one or more provisions of this Agreement is held
to be invalid, illegal or unenforceable, the Parties shall substitute, by mutual consent, valid provisions for such invalid, illegal or unenforceable provisions which valid provisions are, in their economic effect, sufficiently similar to the
invalid provisions that it can be reasonably assumed that the Parties would have entered into this Agreement with such provisions. In the event that such provisions cannot be agreed upon, the invalidity, illegality or unenforceability of one or more
provisions of this Agreement shall not affect the validity of this Agreement as a whole, unless the invalid provisions are of such essential importance to this Agreement that it is to be reasonably assumed that the Parties would not have entered
into this Agreement without such invalid provisions. 

10.8        Interpretation.  The headings for each article and section in this
Agreement have been inserted for convenience of reference only and are not intended to affect its meaning or interpretation. In this Agreement: (a) the word “including” (including any variations such as “includes”) shall be
deemed to be followed by the phrase “without limitation” or like expression; (b) the singular shall include the plural and vice versa; and (c) masculine, feminine, and neuter pronouns and expressions shall be interchangeable.

 10.9        Further Actions.  Each Party agrees to execute,
acknowledge, and deliver any further instruments, and to do all other acts, as may be necessary or appropriate to carry out the purposes and intent of this Agreement. 

10.10      Independent Contractors.  The relationship between the Parties created by this
Agreement is one of independent contractors and shall not constitute or be deemed to constitute a partnership, joint venture, agency, or other fiduciary relationship. Neither Party shall have the authority to make any statements, representations, or
commitments of any kind, or to take any action, that shall be binding on the other Party in whole or in part as a result of this Agreement, without the prior written consent of the other Party to do so. 

10.11      No Warranty.  BY GRANTING THE LICENSES SET FORTH HEREIN, ABI IS NOT MAKING ANY
WARRANTY OF ANY KIND, AND EXPRESSLY DISCLAIMS ALL WARRANTIES, EXPRESS AND IMPLIED, WITH RESPECT TO ABI TECHNOLOGY OR THE LICENSED MARKS, INCLUDING, BUT NOT LIMITED TO, IMPLIED WARRANTIES AND/OR CONDITIONS OF MERCHANTABILITY, NONINFRINGEMENT OR
FITNESS FOR A PARTICULAR PURPOSE. 
 10.12      Limitation of Liability.  IN NO
EVENT SHALL ABI BE LIABLE To AB HEREUNDER FOR INDIRECT, CONSEQUENTIAL, INCIDENTAL, PUNITIVE OR SPECIAL DAMAGES OR LOSSES, INCLUDING BUT NOT LIMITED TO LOST PROFITS, ARISING FROM OR RELATING TO ANY BREACH OF THIS AGREEMENT, REGARDLESS OF ANY NOTICE
OF THE: POSSIBILITY OF SUCH DAMAGES, WHETHER SUCH DAMAGES ARE BASED UPON A BREACH OF EXPRESS OR IMPLIED WARRANTIES, BREACH OF CONTRACT, NEGLIGENCE, STRICT TORT, OR ANY OTHER LEGAL THEORY. 

10.13      Non-Use of Names.  Except as expressly permitted under this Agreement, AB may
not use the name, trade name, trademark or other designation of ABI (including any contraction, abbreviation or simulation of any of the foregoing) or any of its directors, officers, employees and agents in any advertising, publicity, promotional
activities, publication, press release, or other public announcement without the prior written consent of such person or entity in each case. 

 10.14      Language.  This Agreement shall be executed in the
English Language. 
 [Remainder of this page intentionally left blank; signature page follows] 

 IN WITNESS WHEREOF, the Parties have duly executed this Agreement effective as of the day
and year first above written. 

 

 

 Schedule 1 

Patents and Production Strains 

A.  Amyris owned Patents and Patent Applications 
  

							
	 Amyris Ref. No.

 
	 	 Serial
No.
  
	 	 Title

  
	 	
Status
  

	
AM-400 BR
  
	 	 P10712160-1

 
	 	 Fuel Components, Fuel Compositions and Methods of Making and
Using the Same
  
	 	 Based on PCT Application No.
PCT/US2007/012468; Published as WO 2007/139925
  

	 AM-500 BR
	 	 P10713105-4
	 	Production of Isoprenoids	 	 Based on PCT Application No.
PCT/US2007/069807; Published as WO 2007/140339
  

	 AM-700 BR
	 	 P10712508-9
	 	Apparatus for Making a Bio-Organic Compound	 	 Based on PCT Application No.
PCT/US2007/012467; Published as WO 2007/139924
  

	 AM-800 BR
	 	 P10719659-8
	 	 Fuel Compositions Comprising Farnesane and Farnesane Derivatives
and Method of Making and Using the Same
  
	 	Based on PCT Application No. PCT/US2007/021890; Published as WO
2008/045555
	 AM-900 BR
	 	 P10718978-8
	 	Jet Fuel Compositions and Methods of Making and Using the Same	 	 Based on PCT Application No.
PCT/US2007/024266; Published as WO 2008/140492
  

	 AM-1000 PCT
	 	 PCT/US2008/008747

Filed 07/17/2008
	 	 Fuel Compositions Comprising Tetramethylcyclohexane

 
	 	 
	 AM-1200 PCT
	 	 PCT/US2007/024270

Filed 11/20/2007
	 	 Jet Fuel Compositions and Methods of Making and Using the Same

  
	 	Published as WO 2008/133658 on 11/06/2008
	 AM-1400 PCT
	 	 PCT/US2008/010886

Filed 09/19/2008
  
	 	Production of Isoprenoids	 	 
	 AM-1800 PCT
	 	 PCT/US2009/039769

Filed 04/08/2009
  
	 	Expression of Heterologous Sequences	 	 
	 AM-1900 PCT
	 	 PCT/US2009/042183

Filed 04/29/2009
  
	 	 Jet Fuel Compositions and Methods of Making and Using the Same

  
	 	 
	 AM-2100 PCT
	 	 PCT/US2009/004959

Filed 09/01/2009
  
	 	Farnesene Interpolymers	 	 
	 AM-2200 PCT
	 	 PCT/US2009/005158

Filed 09/16/2009
  
	 	Jet Fuel Compositions	 	 
	 AM-2310 PCT
	 	 PCT/US2009/005543

Filed 10/09/2009
	 	 Lubricant Compositions and Methods of Making and Using the Same

  
	 	 
	 AM-2400 PCT
	 	 PCT/US2009/065048
	 	 Compositions and Methods for the Rapid Assembly of
Polynucleotides
  
	 	 
	 AM-3300 PCT
	 	 PCT/US2009/004958

Filed 09/03/2009
	 	 Adhesive Compositions Comprising Polyfarnesene

 
	 	 

 B.  Patents and Patent Applications Licensed from University of California 

 

							
	 Amyris Ref. No.

 
	 	 Serial
No.
  
	 	 Title

  
	 	
Status
  

	 UC-400 BR
	 	 P10510115-8

Filed 05/20/05
	 	Method for Enhancing Production of Isoprenoid Compounds	 	 Based on PCT Application No. PCT/US05/17874;
Published as WO 2006/085899
  

	 UC-500 BR
	 	 P10513837-0

Filed: 07/21/05
	 	Genetically Modified Host Cells and Use of Same for Producing Isoprenoid Compounds	 	 Based on PCT Application No. PCT/US05/026190;
Published as WO 2006/014837
  

	 UC-700 BR
	 	 P10614990-1

Filed: 08/17/06
	 	Genetically Modified Host Cells and Use of Same for Producing Isoprenoid Compounds	 	 Based on PCT Application No.
PCT/US/2006/32406; Published as WO 2007/024718
  

	 UC-1100 BR
	 	 P10716954-0

Filed 09/25/07
	 	Production of Isoprenoids and Precursors Thereof	 	 Based on PCT Application No.
PCT/US/2007/020790; Published as WO 2008/039499
  

C.  Production Strains 
  

	 	o	 [*] 

	 	o	 [*] 

	 	o	 [*] 

	 	o	 [*] 

	 	o	 [*] 

	 	o	 [*] 

	 	o	 [*] 

	 	o	 [*] 

	 	o	 [*] 

	 	o	 [*] 

	 	o	 [*] 

	 	o	 [*] 

	 	o	 [*] 

	 	o	 [*] 

	 	o	 [*] 

  

	*	 Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been
requested with respect to the omitted portions. 

 Schedule 2 

Logo 

 

 

 Schedule 3 

Additional Trademarks 
  

									
	Mark	  	Country	  	 Application
Number

 
	  	Filing Date	  	Status
	 AMYRIS

(Class 4)
  
	  	 BR
	  	 900766638
	  	 02/28/2008
	  	Extension based on Registration No. 1R948423 on 12/20/2007
	 AMYRIS

(Class 42)
  
	  	 BR
	  	 900766654
	  	 02/28/2008
	  	Extension based on Registration No. 1R 948424 on 12/20/2007
	 DIAL-A-BLEND

(Class 4)
  
	  	 BR
	  	 900766719
	  	 02/28/2008
	  	 
	 DIAL-A-BLEND

(Class 9)
  
	  	 BR
	  	 900766735
	  	 02/28/2008
	  	 
	 NO COMPROMISE

(class 4)
  
	  	 BR
	  	 901470945
	  	 02/20/2009
	  	 

 Schedule 4  

Requirements for Use of Licensed Marks 
  

	1.	 The Licensed Marks shall be used in all upper ease letters, so as to distinguish them from the surrounding text. 

 

	2.	 The first or most prominent reference to the Licensed Marks shall be marked with a
® or TM symbol, as appropriate. 

 

	3.	 The Licensed Marks shall not be used in possessive form. 

 

	4.	 The Licensed Marks shall not be used in the plural form. 

 

	5.	 The Licensed Marks can be used jointly with other marks. 

 EXHIBIT 2 

SHAREHOLDERS AGREEMENT 

[See Exhibit 4.06 to the Registration Statement on Form S-1 filed by Amyris, Inc. with the Securities and 

Exchange Commission, File No. 333-166135]Amendment and Restatement to the Shareholders' Agreement

 Exhibit 4.06 

Execution Version 

AMENDMENT AND RESTATEMENT TO THE SHAREHOLDERS’ AGREEMENT 

BY 
 FUNDO
MÚTUO DE INVESTIMENTOS EM EMPRESAS EMERGENTES INOVADORAS 
 STRATUS GC III, 

RED MOUNTAIN JET LLC, 

AMYRIS BIOTECHNOLOGIES, INC., 

AND, AS INTERVENING PARTIES, 

AMYRIS BRASIL S.A. 

AND 
 STRATUS
INVESTIMENTOS LTDA. 
 MAY 26, 2010 

 Execution Version 

 

 AMENDMENT AND RESTATEMENT TO THE SHAREHOLDERS’ AGREEMENT 

This amendment and restatement to the Shareholders’ Agreement (this “Amendment”) is executed on May 26, 2010, by the following
parties (all of them, collectively, the “Parties”, and individually, a “Party”): 
  

	(1)	FUNDO MÚTUO DE INVESTIMENTO EM EMPRESAS EMERGENTES INOVADORAS STRATUS GC III (“Stratus”), a fund duly authorized by CVM according to
Oficio n° 2607/06, dated November 23, 2006, registered with the CNPJ/MF under n° 08.083.268/0001-46, herein represented by Stratus Gestão de Carteiras Ltda. (“SGC”), a company incorporated and existing
under the laws of Brazil, with head offices in the city of São Paulo, State of São Paulo, at Rua Funchal, 129,
13th floor, suite B, Vila Olímpia, registered with
the CNPJ/MF under n° 09.238.656/0001-11, authorized by CVM for the rendering of management of portfolio services, according to Ato Declaratório n° 9.808, dated April 28, 2008, herein represented in accordance with its
regulations; 

  

	(2)	RED MOUNTAIN JET LLC, a company incorporated and existing under the laws of State of Delaware, with head offices at 16192 Coastal Highway, Lewes, Delaware 19958,
United States of America, herein represented by its undersigned representatives (“Red Mountain”) 

  

	(3)	AMYRIS BIOTECHNOLOGIES, INC., a company incorporated and existing under the laws of the State of California, United States of America, with head offices at 5980
Hollis Street, Suite 100, Emeryville, California 94608, herein represented by its undersigned representatives (“ABI”); 

And, as intervening parties, 
  

	(4)	AMYRIS BRASIL S.A., a company incorporated and existing under the laws of Brazil, with head offices in the city of Campinas, state of São Paulo, at Rua
James Clerk Maxwell, n° 315, Techno Park, CEP 13069-380, registered with the CNPJ/MF under n° 09.379.224/0001-20, herein represented by its undersigned representatives (“AB” or the “Company”); and

  

	(5)	STRATUS INVESTIMENTOS LTDA., Stratus’s administrator (administradora), a company incorporated and existing under the laws of Brazil, with head
offices in the city of São Paulo, State of São Paulo, at Rua Funchal, 129,
13th floor, suite B, Vila Olímpia, registered with
the CNPJ/MF under n° 02.263.285/0001-89, herein represented by its undersigned representatives (“SIL”). 

WHEREAS, on December 22, 2009, Stratus, ABI, AB and SIL entered into a Shareholders’ Agreement, in order to govern the relationship
between Stratus and ABI, as shareholder of the Company (the “Agreement”), 
 WHEREAS Red Mountain has also made capital
contributions into the Company, thus becoming one of its shareholders and subject to the rules set forth in the Agreement, 
  

 1 

 Execution Version 

 

 WHEREAS, besides including Red Mountain as a party of the Agreement, the Parties intend to
further agree on a conversion right for the Investors (as defined in this Amendment), to convert their shares of AB into shares of ABI, under certain circumstances, 

WHEREAS the Parties intend to alter certain other terms of the Agreement, 

Now, therefore, the Parties hereby decide to amend the Agreement, as set forth below. 

1.        Parties. Red Mountain shall be deemed as a Party to the Agreement and, thus any reference to the
Parties contained in the Agreement shall hereinafter include Red Mountain. 
 2.        Definitions.
The Parties agree to amend Section 1.1 of the Agreement, in order to exclude and modify certain definitions contained therein and to insert new definitions, as follows: 

2.1.     The Parties agree to modify the following definitions of Section 1.1 of the Agreement, which shall
hereinafter be read as follows: 
 “AB Post-Money Valuation” means the sum of (i) the AB Pre-Money Valuation,
(ii) the ABI Cash Contribution, and (iii) the Investors Cash Contribution. 
 “AB Pre-Money Valuation” means
R$180,000,000 (one hundred and eighty million Brazilian Reais) which represents the value of the Company, agreed on by the Parties, after the ABI Technology Contribution and before the ABI Cash Contribution and the Investors Cash Contribution. 

 “Closing” means the date on which Stratus has made its capital contribution to the Company. 

“Conditions for Distribution” means the following conditions necessary to allow AB to distribute capital (dividends or interest on
capital (juros sobre capital próprio) to the Shareholders: (a) all legal requirements for distribution of capital under Brazilian laws, including the existence of net profits or distributable capital reserves, are complied with; and
(b) the Company has cash immediately available for the distribution. 
 “Investors” jointly, Stratus, Red Mountain
and all the qualified third party investors appointed by ABI, SGC or SIL, which are on this date or become a direct or indirect shareholder of the Company, who shall invest the Investors Cash Contribution. 

“Share” means a common share issued by the Company and held by the Shareholders as well as any other shares issued by the Company
which the shareholders may subscribe, receive or otherwise acquire in the future during the term of this Agreement. 

“Shareholders” means the shareholders of AB, which are subject to the terms and conditions of this Agreement. 

“Total Contribution Amount” means that amount equal to (i) the ABI Cash Contribution, plus (ii) the Investors Cash
Contribution. 

 Execution Version 

 

	2.2.     The	Parties agree to insert the following definitions in Section 1.1 of the Agreement: 

“ABI Conversion Notice” shall have the meaning set forth in the section 7.3 hereto. 

“Red Mountain” shall have the meaning set forth in the Preamble. 

2.3.     The Parties agree to exclude the following definitions from Section 1.1 of the Agreement and accordingly
agree to exclude all references to such definitions contained throughout the Agreement: “ABI Additional Contributions”, “ABI Mill Contribution”, “Investment Agreement”, “Usina Boa
Vista”. 
 2.4.     The Parties decide to rename the definitions “Investor Offer
Notice” and “Investor Offered Shares”, so that they shall now read “Investors Offer Notice” and “Investors Offered Shares”. The meaning of both of these renamed definitions shall remain the
same. 
 3.        Additional language to Section 2.2.   The Parties agree to add
additional language to Section 2.2 of the Agreement, which shall from now on the read as follows: 

“2.2    Scope of this Agreement. 

The scope of this Agreement is to establish the terms and conditions that shall rule the relationship of the Shareholders of the Company, including:
(i) management and corporate governance of the Company, (ii) voting rights, (iii) conditions applicable to the Transfer of Shares, and (iv) a possible IPO of the Company. 

2.2.1    Capital ownership 

For future reference regarding the capital ownership of the Company, parties should refer to the copy of the Company’s share
registry book as of this date, which is attached to this Agreement as Exhibit I.” 

4.        Observer Seat at the Board of Directors and Related Provisions. The Parties agree that as long
as Red Mountain is a Shareholder of the Company, it shall be entitled to 1 (one) non-voting observer at the Company’s Board of Directors. Therefore, Section 4.3 of the Agreement shall be amended accordingly and shall hereinafter be read as
follows: 
 “4.3    Election of the Board of Directors. 

The Board of Directors shall consist of 5 (five) directors appointed as follows: (i) ABI shall be entitled to appoint 3 (three) directors;
(ii) the Investors shall be entitled to appoint 1 (one) director as long as the amount of Investors’ cash contribution into the Company corresponds to at least 10% (ten per cent) of the sum of the Total Contribution Amount and all future
contributions made into the Company, provided that all Investors shall vote as block to elect such director; and (iii) 1 (one) independent director; with substantial experience in the Brazilian sugar and ethanol sector, shall be unanimously
appointed by the other directors. The Shareholders’ undertake to approve the election of the directors appointed in accordance with the conditions established in this section, for a term of office of 2 (two) years, being re-election permitted.

 Execution Version 

 

 4.3.1 Resignation of the Director Appointed by the Investors. 

Whenever the amount of the Investors’ cash contribution into the Company falls below 10% (ten per cent) of the sum of the Total
Contribution Amount and all future contributions made into the Company, the Board of Directors may require the resignation of the director appointed by it, in which case the Board of Directors will consist of 4 (four) directors after the
resignation. 
 4.3.2 Observer Seat at the Board of Directors. 

4.3.2.1 Stratus. 

Whenever Stratus is not able to elect a member of the Board of Directors, it shall be entitled to 1 (one) non-voting observer at the
Board of Directors. 
 4.3.2.2 Red Mountain. 

As long as Red Mountain is a Shareholder of the Company, it shall be entitled to 1 (one) non-voting observer at the Board of
Directors.” 
 5.        Board of Officers. The Parties agree that the Company’s
Board of Directors shall no longer be required to appoint a chief operational officer (Diretor de Operações). Therefore, Section 4.5 of the Agreement shall be amended accordingly and henceforth read as follows: 

“4.5    Board of Officers 

The initial Board of Officers shall consist of either one Chief Executive Officer (“CEO”) or one officer superintendent (Diretor
Superintendente), one Financial Officer (Diretor Financeiro) and such additional senior management as may be necessary. The Board of Officers shall be responsible for routine management of the activities of the Company. The members of the Board of
Officers shall perform their duties in accordance with applicable laws, the by-laws of the Company, and any internal guidelines of the Company (including instructions given by the Board of Directors). The Board of Directors may alter the composition
of the Board of Officers from time to time by majority vote.” 
 6.        Additional
language to Section Five. The Parties agree to add additional wording to Sections 5.3, 5.4, 5.5, 5.6 and 5.8 which shall, henceforth, read as follows: 

“5.3    Right of First Refusal for Acquisition of the Investors’ Shares. 

If any Investor wishes, directly or indirectly, to Transfer some or all of its Shares (the “Investor Offered Shares”), it must offer
such Investor Offered Shares to ABI in accordance with the following provisions: 
  

	(a)	 The Investor shall deliver a notice (“ABI Offer Notice”) to ABI stating (i) its bona fide intention to offer such Investor
Offered Shares, (ii) the number of such Investor Offered Shares to be offered, (iii) the price and terms, if any, upon which it proposes to offer such Investor Offered Shares, and (iv) when applicable, the identity of any third party
who has offered to buy such Investor Offered Shares and a copy of the offer received from such 

 Execution Version 

 

	 	 
third party, as long as ABI accepts in writing to be subject to the confidentiality requirements established by the Investor and the third party. 

 

	(b)	The Investor’s offer shall remain effective for acceptance by ABI for a period of 30 (thirty) days, as of the date of receipt of the Offer Notice, unless
earlier waived by ABI (the “ABI Acceptance Period”). During the ABI Acceptance Period, ABI shall have the right to accept all, but not less than all of the Investor Offered Shares, by giving written notice to the Investor who wishes
to sell its Shares. The failure by ABI to reply to the ABI Offer Notice within the ABI Acceptance Period shall be deemed as the non-exercise of its right of first refusal. 

 

	(c)	If ABI does not exercise its right of first refusal, the Investor shall have the right, exercisable not later than 90 (ninety) days following the expiration of the
ABI Acceptance Period, to consummate the Transfer of the Investor Offered Shares to a third party on the same terms and conditions of the offer presented to ABI in the ABI Offer Notice. If the Investor does not consummate such Transfer within such
90 (ninety) day period, the Investor Offered Shares shall again be subject to the terms, conditions and restrictions set forth in this section 5.3. 

5.4    Right of First Refusal for Acquisition of ABI’s Shares. 

If ABI wishes, directly or indirectly, to Transfer some or all of its Shares (the “ABI Offered Shares”), it must offer such ABI
Offered Shares to the Investors in accordance with the following provisions: 
  

	(a)	ABI shall deliver a notice (“Investors Offer Notice”) to the Investors stating (i) its bona fide intention to offer such ABI Offered Shares,
(ii) the number of such ABI Offered Shares to be offered, and (iii) the price and terms, if any, upon which it proposes to offer such ABI Offered Shares and (iv) when applicable, the identity of any third party who has offered to buy
such ABI Offered Shares and a copy of the offer received from such third party, as long as the Investors accept in writing to be subject to the confidentiality requirements established by ABI and the third party. 

 

	(b)	ABI’s offer shall remain effective for acceptance by the Investors for a period of 30 (thirty) days, as of the date of receipt of the Investors Offer Notice,
unless earlier waived by the Investors and subject to the additional term provided for in section 5.4(d), if applicable, (the “Investors Acceptance Period”). During the Investors Acceptance Period, the Investors shall have the right
to accept all, but not less than all of the ABI Offered Shares, by giving written notice to ABI. The failure by the Investors to reply to the Investors Offer Notice within the Investors Acceptance Period shall be deemed as the non-exercise of the
right of first refusal by the Investors. 

  

	(c)	 If the Investors do not exercise their right of first refusal, ABI shall have the right, exercisable not later than ninety (90) days following
the expiration of the Investors Acceptance Period, to consummate the Transfer of the ABI Offered Shares to a third party on the same terms and conditions of the offer presented to the Investors in the Investors Offer Notice. If ABI does not
consummate such Transfer within the mentioned 

 Execution Version 

 

	 	 
ninety (90) day period, the ABI Offered Shares shall again be subject to the terms, conditions and restrictions set forth in this section 5.4. 

 

	(d)	Each Investor shall have the right to accept to acquire a number of the ABI Offered Shares proportional to their equity participation in the Company. If one or more
Investors accept to acquire their pro rata share of the ABI Offered Shares (the “Accepting Investors”), but one or more Investors refuse to acquire such Shares, then the Accepting Investors shall have the right to acquire the
refused part of the ABI Offered Shares, also on a pro rata basis, according to their equity participation in the Company. The Accepting Investors shall have additional 15 (fifteen) days to accept to acquire all remaining ABI Offered Shares. The
failure by the Accepting Investors to accept all, but not less than all remaining ABI Offered Shares within such additional period shall be deemed as the non-exercise of all Investors’ right of first refusal under this section 5.4.

 5.5     Tag Along Rights. 

If, subject to the provisions of sections 5.3 or 5.4 above, ABI decides to Transfer the Control of the Company to a third party, other than to an
Affiliate and in a way that ABI ceases to hold the direct or indirect Control of the Company, in one transaction or in a series of transactions (whether related or not), by contract or otherwise, each of the Investors shall have the right to sell
all of its Shares to the same third party, together with the Shares Transferred by ABI, at the same terms, conditions, price and form of payment (“Tag Along Right”), according to the following procedure: 

 

	(a)	ABI shall present to the Investors a notice, which shall include the identity of the acquiring third party, the proposed sale price per Share and any other terms and
conditions of the intended Transfer, including a copy of the offer received by ABI, when applicable (“Tag Along Notice”). 

  

	(b)	Each of the Investors shall have the right to exercise its Tag Along Right during a period of 30 (thirty) days, as of the date of receipt of the Tag Along Notice, by
giving written notice to the transferring Shareholder, being the failure of doing so interpreted as non- exercise of such right. 

5.6     Drag Along Rights. 

If, subject to the provisions of section 5.4 above and section 5.8 below, ABI decides to Transfer all of its Shares to any third party, ABI may compel
all the Investors to sell all of their Shares to the same third party, together with the Shares Transferred by ABI, at the same terms, conditions, price and form of payment. ABI shall provide the identity of any third party who has offered to buy
its Shares and a copy of the offer received from such third party, as long as the Investors accept in writing to be subject to the confidentiality requirements established by ABI and the third party. 

For ABI to be able to exercise the Drag Along Rights provided for in this section, the price to be paid to each of the Investors for the Shares to be
transferred upon such exercise may not be lower than their pro rata share of the Put Option Price provided for on section 5.8, The Change 

 Execution Version 

 

 
of Put Option Price provided for on section 5.8.1 shall also be applicable in case of exercise of Drag Along Rights under this section. 

 

	  	... 

5.8     Change of Control of AB. 

If the Company undergoes a Change of Control Event in which the Investors’ pro rata share of the Acquisition Price is lower than the Minimum
Investors’ Return, each Investor will have a put option against ABI. Such put option will be exercisable within 10 (ten) days, as of the receipt by the Investors of a notice sent by ABI informing that it has received a binding offer from one or
more third parties willing to acquire the control of AB through a Change of Control Event (the “Third Party Acquirer”), and will entitle the Investors to sell all their Shares to ABI, for a total amount equal to the Put Option
Price. Each of the Investors shall have the right to receive from ABI its pro rata share of the total Put Option Price, in accordance with its respective equity participation in AB determined as of the date the put option is exercised. The Put
Option Price shall be paid by ABI to each Investor within 5 (five) business days of receipt by ABI of the effective payment, made by the Third Party Acquirer or by AB, of the sale proceeds arising from said Change of Control Event. 

5.8.1  Change of Put Option Price. 

In the event AB is valued at the Minimum Future AB Pre-Money Valuation in connection with a Change of Control Event or an IPO of AB,
the price of the put option held by the Investors, in the situation described in this section 5.8, shall be the lower of (i) the amount invested by the Investors in AB in Brazilian Reais; and (ii) the total amount of proceeds actually
received by ABI from a third party acquirer or from AB, in connection with a Change of Control Event relating to the Company. 

7.        Minor adjustments to Section 6.   The Parties agree to amend Sections 6.1 and
6.3, which shall henceforth read as follows: 
 “6.1    Approval of the IPO. 

The Shareholders hereby commit to vote in a Shareholders’ Meeting in order to approve an IPO of the Company, after 4 (four) years of the Closing,
as long as market conditions are favourable for an IPO, as determined by an internationally recognized investment bank to be selected by the Board of Directors. 

(...) 

6.3     Secondary Offers by the Shareholders. 

In the event the investment bank coordinating the IPO recommends that the IPO may include the offer of shares held by the shareholders (secondary
offering), each of the Investors shall have the right to participate of such secondary offering, through the public offer of their Shares jointly with the Company’s primary offer at the time of the IPO, pro rata to their then stock
ownership.” 

 Execution Version 

 

 8.        Additional wording on Section 7.
  The Parties agree to amend Sections 7.1(i) 7.2 and 7.3, of the Agreement, which shall henceforth read as follows: 

“7.1    ABI Change of Control Event. 

 

	  	... 

  

	(i)	Each of the Investors shall have the right to convert all, and not less than all of its Shares in AB to shares of ABI common stock at the Conversion Ratio by
providing written notice to ABI of its desire to carry out the conversion within ten (10) business days of receipt of a written notice by ABI, explaining the general terms of the transaction underlying the Change of Control Event, the
identification of the potential acquirer(s), the expected closing date and the consideration to be provided for the acquisition of Control in AB (“ABI Change of Control Notice”); 

... 

7.2     ABI IPO. 

Subject to the restrictions on the transfer of AB’s Shares set forth in Section Five above, in the event of an ABI IPO, each of the Investors
shall have the following rights: 
 (...) 

7.3.     ABI’s Call for Conversion. 

ABI shall have the right to require the Investors to exchange some or all of their Shares in AB for restricted shares of ABI common stock, at the
Conversion Ratio, in the event ABI is valued at least U.S. $ 500,000,000 (five hundred million United States dollars) in connection with an ABI IPO or an ABI Change of Control Event. In that case, ABI shall provide written notice to the Investors of
its desire to carry out the conversion no later than ten (10) days prior to the closing of the transaction in connection with which the conversion is being required (the “ABI Conversion Notice”). The conversion will be effective
immediately prior to the closing of the relevant transaction. The Investors shall (i) enter into the applicable agreement for effecting the conversion (in reasonable form provided by ABI), (ii) in the event the triggering transaction is an
ABI IPO, enter into any lock-up agreement and/or plan of sale documents required by the underwriters, and (iii) enter into and deliver such other documents as are necessary to cause the relevant transaction to be completed. The Investors
further agree to provide such information as may be requested by ABI to ensure compliance with all applicable laws, including securities laws. Each Party agrees to take such further actions as are necessary to cause the conversion of shares to be
consummated. 
 7.3.1    Each Party agrees to use reasonable efforts to cause
the conversion of shares to be consummated in such a way that would maximize benefits for each of the Parties. 

7.3.2    In the event the conversion required under this section 7.3, cannot be carried out
due to regulatory restrictions applicable to ABI or one of the Investors, the parties shall use reasonable efforts to agree on a mechanism, within 30 (thirty) days of receipt of the 

 Execution Version 

 

 
ABI Conversion Notice, by which the Investors would (i) cease to be shareholders of AB; and reach the same economic results as if they had converted their Shares into shares of ABI as
provided herein. In any case, no regulatory restriction applicable to the Investors, nor the failure of any of the Investors to comply with any obligation provided for in the Agreement, especially those provided for in this Section 7.3 shall
prevent ABI from exercising the right set forth in this section. 
 9.        Conversion Right.
The Parties agree to include in the Agreement a new Section Eight and to accordingly renumber the other subsequent Sections. The new Section shall read as follows: 

“SECTION EIGHT 

RIGHT TO CONVERT INTO ABI STOCK 

8.1.     Right to Convert into ABI stock 

 

	(i)	In case, by December 31, 2012, any of the Investors who remain as Shareholders of AB, having not converted their shares in AB to shares of ABI common stock
pursuant to Section 7.1 in connection with a Change of Control of ABI, or pursuant to Section 7.2 or Section 7.3 in connection with an ABI IPO, such Investor will have the right to convert its Shares of AB into shares of ABI common
stock, at the Conversion Ratio, subject to compliance by ABI and the Investors with all applicable laws (including securities laws). 

  

	(ii)	The Investors will have fifteen (15) days from the abovementioned date to provide ABI with notice of their intention to convert their Shares of AB into shares
of ABI common stock. ABI shall endeavor to use reasonable efforts to carry out the exchange of shares within ninety (90) days after the deadline provided for in this paragraph has elapsed. 

8.2     The Parties agree that the right of the Investors to convert their Shares of AB into shares of
ABI common stock, provided for in section 8.1 above, is fully conditioned and inherent to the fact that they are (i) shareholders of AB and (ii) part of this Agreement, so that this right, as well as any other rights or obligations arising
out of this Agreement may not be transferred to any third party without the Parties’ prior consent. Any assignment of rights in disregard with this provision shall be rendered null and void. 

10.     Notices to Red Mountain. The Parties agree to amend the Section 11.6 of the Agreement to add that, if to Red
Mountain, the notices to be sent pursuant to the Agreement shall be sent to the following address: 
 “If to Red Mountain:

 PEDRO PAULO FALLEIROS DOS SANTOS DINIZ 

Address: Rua Jerônimo da Veiga, 384,
3rd floor 

Telephone: +55 11 3702-5161 
 Fax: +55
11 3702-5112 
 E-mail: pedro@ppdholding.com” 

 Execution Version 

 

 Copy to: 

KLA- Koury Lopes Advogados 
 Address:
Avenida Brigadeiro Faria Lima, 1355, 18th floor 
 Telephone: +55 11 3799-8118 

Fax: +55 11 3799-8200 
 E-mail:
mcortez@klalaw.com.br 
 Attn.: Mariana Machado Cortez 

11.     Consolidation. For the avoidance of doubt, the Parties decide to consolidate a final version of the Agreement,
which shall from now on be read as follows: 
 “SHAREHOLDERS’ AGREEMENT 

This Shareholders’ Agreement, as amended from time to time (this “Agreement”), is executed by the following parties (all of them,
collectively, the “Parties” and individually, a “Party”): 
  

	(1)	FUNDO MÚTUO DE INVESTIMENTO EM EMPRESAS EMERGENTES INOVADORAS STRATUS GC III (“Stratus”), a fund duly authorized by CVM according to
Oficio n° 2607/06, dated November 23, 2006, registered with the CNPJ/MF under n° 08.083.268/0001-46, herein represented by Stratus Gestão de Carteiras Ltda. (“SGC”), a company incorporated and existing
under the laws of Brazil, with head offices in the city of São Paulo, state of São Paulo, at Rua Funchal, 129,
13t
h floor, suite B, Vila Olímpia, registered with the CNPJ/MF under n° 09.238.656/0001-11, authorized by
CVM for the rendering of management of portfolio services, according to Ato Declaratório n° 9.808, dated April 28, 2008, herein represented in according with its regulations; 

 

	(2)	RED MOUNTAIN JET LLC, a company incorporated and existing under the laws of State of Delaware, with head offices at 16192 Coastal Highway, Lewes, Delaware 19958,
United States of America, herein represented by its undersigned representatives (“Red Mountain”) 

  

	(3)	AMYRIS BIOTECHNOLOGIES, INC., a company incorporated and existing under the laws of the State of California, United States of America, with head offices at 5980
Hollis Street, Suite 100, Emeryville, California 94608, herein represented by its undersigned representatives (“ABI”); 

And, as intervening parties, 
  

	(4)	AMYRIS BRASIL S.A., a company incorporated and existing under the laws of Brazil, with head offices in the city of Campinas, state of São Paulo, at Rua
James Clerk Maxwell, n° 315, Techno Park, CEP 13069-380, registered with the CNPJ/MF under n° 09.379.224/0001-20, herein represented by its undersigned representatives (“AB” or the “Company”); and

  

	(5)	STRATUS INVESTIMENTOS LTDA., Stratus’s administrator (administradora), a company incorporated and existing under the laws of Brazil, with head
offices in the city of São Paulo, at Rua Funchal, 129,
13th floor, suite B, Vila Olímpia, registered with
the CNPJ/MF under n° 02.263.285/0001-89, herein represented by its undersigned representatives (“SIL”). 

 Execution Version 

 

 WHEREAS ABI and the Investors (as defined below) have made capital contributions into the Company
and intend to establish the rules that shall govern their relationship as shareholders of the Company, 
 WHEREAS ABI and the Investors
(as defined below) have made capital contributions into the Company and intend to establish the rules that shall govern their relationship as shareholders of the Company, 

Now, therefore, the Parties hereby decide to enter into this Agreement, which shall be governed by the following terms and conditions: 

SECTION ONE 

DEFINITIONS AND INTERPRETATION 

1.1     Definitions: 

“AB” has the meaning set forth in the Preamble. 

“AB Competitor” means any person or entity that has current or prospective business activities or interests that, in ABI’s
reasonable judgment, are competitive with the business of the Company. 
 “AB Post-Money Valuation” means the sum of
(i) the AB Pre-Money Valuation, (ii) the ABI Cash Contribution, and (iii) the Investors Cash Contribution. 
 “AB
Pre-Money Valuation” means R$180,000,000 (one hundred and eighty million Brazilian Reais) which represents the value of the Company, agreed on by the Parties, after the ABI Technology Contribution and before the ABI Cash Contribution and
the Investors Cash Contribution. 
 “ABI” has the meaning set forth in the Preamble. 

“ABI Acceptance Period” has the meaning set forth in section 5.3(b) hereto. 

“ABI BDRs” means Brazilian Depositary Receipts tracking to ABI stock that is issued and publicly traded in the United States.

 “ABI Cash Contribution” means a cash contribution of US$ 10,000,000 (ten million United States dollars) to be made by ABI in
AB. 
 “ABI Change of Control Notice” has the meaning set forth in section 7.1(i) hereto. 

“ABI Conversion Notice” shall have the meaning set forth in the section 7.3 hereto. 

“ABI IPO” means an initial public offering of the shares issued by ABI, at a value determined through a book-building process by
internationally recognized investment banks to be selected by the ABI’s management, either relating to shares newly issued by ABI for the offering (primary offering) or shares held by ABI’s shareholders and publicly offered by such
shareholders (secondary offering), or a combination of both. 

 Execution Version 

 

 “ABI Offer Notice” has the meaning set forth in section 5.3(a) hereto. 

“ABI Offered Shares” has the meaning set forth in section 5.4 hereto. 

“Accepting Investors” has the meaning set forth in section 5.4(d) hereto. 

“Acquisition Price” means the purchase price to be paid by the acquirer/buyer to the seller in connection with a Change of Control
Event. 
 “Affiliate” of a certain Person (the “first Person”) means a Person that directly or indirectly through one
or more intermediaries, Controls, or is Controlled by, or is under common Control with, the first Person. 
 “Agreement” has
the meaning set forth in the Preamble. 
 “Amyris Renewable Products” means renewable chemical and fuel products to be
manufactured by AB through the use of Amyris Technology under the terms and conditions set forth in the Technology License. 
 “Amyris
Technology” means ABI’s proprietary microbial production technology which converts simple sugars derived from various plant sources, including sugarcane, into specific compounds of interest, with respect to which certain exclusive and
non-exclusive rights were transferred by ABI to AB by means of the Technology License. 
 “Block Sale” means any individual
sale or sequence of sales within a one (1)-year time frame, under which at least twenty percent (20%) of the Company’s shares are sold to one single entity or to a group of different entities subject to common Control. 

“Board of Directors” means the board of directors (“Conselho de Administração”) of the Company.

 “Board of Officers” means the board of officers (“Diretoria”) of the Company. 

“Bovespa” means the São Paulo stock exchange (Bolsa de Valores, Mercadorias e Futuros - BM&FBovespa). 

“Bovespa Mais” means a certain listing segment of Bovespa. 

“Brazilian Civil Procedure Code” means law No. 5,869, enacted on January 11, 1973, as amended from time to time. 

“Brazilian Corporation Law” means law No. 6,404, enacted on December 15, 1976, as amended from time to time. 

“Business Plan and Budget” means a written two-(2)-year business, operational and strategic plan governing the operation of the Company,
including strategic plans for capital requirements 

 Execution Version 

 

 
and capital expenditures for each of the two (2) years; a capital budget for each of the two (2) years; and an operating budget for the relevant year. 

“Change of Control Event” means, with respect to an entity, (i) a merger, reorganization, consolidation or other transaction (or
series of related transactions of such nature) pursuant to which more than fifty percent (50%) of the voting power of all outstanding equity securities of the entity is transferred by the holders of such entity’s outstanding shares
(excluding a reincorporation to effect a change in domicile), (ii) a sale of all or substantially all of the assets of the entity, or (iii) any other transaction or series of related transactions, in which the entity’s shareholders
immediately prior to such transaction or transactions own immediately after such transaction less than fifty (50%) of the voting equity securities of the surviving corporation or its parent. 

“Company” has the meaning set forth in the Preamble. 

“Conditions for Distribution” means the following conditions necessary to allow AB to distribute capital (dividends or interest on
capital (juros sobre capital próprio) to the Shareholders: (a) all legal requirements for distribution of capital under Brazilian laws, including the existence of net profits or distributable capital reserves, are complied with;
and (b) the Company has cash immediately available for the distribution. 
 “Control” of an entity means the power to
direct the management and policies of such entity and shall be presumed to exist upon ownership of securities entitling the holder thereof to exercise more than 50% (fifty per cent) of the voting power in the election of directors and in the
decision of any strategic matter of such entity. 
 “Conversion Ratio” shall mean 0.28 (twenty-eight hundredths) shares of ABI
per each 1 share of AB. 
 “Closing” means the date on which Stratus has made its capital contribution to the Company.

 “Encumbrance” means any claim, charge, mortgage, lien, option, power of sale, usufruct, right of pre-emption, right of first
refusal or other third party rights or security interest of any kind or an agreement, arrangement or obligation to create any of the foregoing. 

“Investors” means, jointly, Stratus, Red Mountain and all the qualified third party investors appointed by ABI, SGC or SIL, which are on
this date or become a direct or indirect shareholder of the Company, who shall invest the Investors Cash Contribution. 
 “Investors
Acceptance Period” has the meaning set forth in section 5.4(b) hereto. 
 “Investors Cash Contribution” means the
capital investments in AB that the Investors are entitled to make in an amount up to the lesser of (i) US$ 32,500,000 (thirty-two million, five hundred thousand United States dollars), and (ii) that amount equal to twenty percent
(20%) of the AB Post-Money Valuation (as defined above). 
 “Investor Offer Notice” has the meaning set forth in section
5.4(a) hereto. 

 Execution Version 

 

 “Investor Offered Shares” has the meaning set forth in section 5.3 hereto. 

“IPO” means the initial public offering of Shares of the Company, at a value determined through a book-building process by
internationally recognized investment banks to be selected by the Company, either relating to Shares newly issued by the Company for the offering (primary offering) or Shares held by the Shareholders and publicly offered by such Shareholders
(secondary offering), or a combination of both, after which the Company shall be listed at Bovespa. 
 “Minimum Future AB Pre-Money
Valuation” means an amount representing the value of the Company, according to which the Investors’ equity participation in AB would value more than the Minimum Investors’ Return in Brazilian Reais. 

“Minimum Investors’ Return” means the amount invested by the Investors in AB in Brazilian Reais, plus 8% (eight per cent) per year.

 “Off-Exchange Sale” means any sale of the Company’s shares, after the Company is publicly listed and traded in Brazil,
that is not within Bovespa. 
 “Parties” has the meaning set forth in the Preamble. 

“Person” means any individual, corporation, partnership, limited liability company, firm, joint venture, association, joint stock
company, trust, unincorporated organization, governmental or regulatory body or subdivision thereof, or any other entity. 
 “Put Option
Price” means the lower of (i) the Minimum Investors’ Return; and (ii) the total amount of proceeds actually received by ABI from a third party acquirer or from AB, in connection with a Change of Control Event relating to the
Company. 
 “Red Mountain” has the meaning set forth in the Preamble. 

“Related Party” means, with respect to any Person, (i) its Affiliates, (ii) a spouse, parent, grandparent, descendant or
sibling of such Person, (iii) any other Person owning twenty percent (20%) or more of the issued and outstanding equity securities of such Person, and (iv) any other Person Controlled by the Affiliates of such Person. 

“Related Party Transaction” means any transaction between the Company, on the one hand, and any Related Party, on the other hand, or
entered into by the Company for the benefit of a Related Party. 
 “Rules of Arbitration” has the meaning set forth in section
12.2 hereto. 
 “Shareholders” means the shareholders of AB, which are subject to the terms and conditions of this Agreement.

 “Shareholders’ Meeting” means a shareholders’ meeting of the Company, either annual (ordinary) or extraordinary.

 Execution Version 

 

 “Share” means a common share issued by the Company and held by the Shareholders as well
as any other shares issued by the Company which the Shareholders may subscribe, receive or otherwise acquire in the future during the term of this Agreement. 

“SGC” has the meaning set forth in the Preamble. 

“SIL” has the meaning set forth in the Preamble. 

“Stratus” has the meaning set forth in the Preamble. 

“Tag Along Notice” has the meaning set forth in section 5.5(a) hereto. 

“Tag Along Right” has the meaning set forth in section 5.5 hereto. 

“Technology License” means that certain Technology License Agreement between ABI and the Company effective as of March 27, 2008.

 “Third Party Acquirer” has the meaning set forth in section 5.8 hereto. 

“Total Contribution Amount” means that amount equal to (i) the ABI Cash Contribution, plus (ii) the Investors Cash
Contribution. 
 “Transfer” (including the terms “Transfer”, “Transferring” and “Transferred”)
means (i) any direct or indirect transfer, sale, assignment (including assignment of pre-emptive rights), exchange, donation or other disposition of any kind, voluntary or involuntary, contingent or non-contingent, including any transfer, sale,
assignment, exchange, donation or other disposition of any kind that results from the foreclosure of any pledge, mortgage, grant of security interest or Encumbrance, or in connection with any merger, consolidation, spin-off, reorganization,
amalgamation, issuance of equity securities or other transactions having a similar effect, (ii) entering into any agreement for the direct or indirect transfer of the voting rights attached to any Shares; and (iii) any agreement (whether
or not subject to conditions) to do or create or grant any of the foregoing. 
 1.2     Interpretation.

 A reference in this Agreement to the singular includes a reference to the plural and vice versa. The term “including” shall be
deemed to be followed by the phrase “but not limited to”. The words “hereof’, “herein”, “hereto”, “hereunder” and similar words refer to this Agreement as a whole. The headings of this Agreement are
included for convenience purposes only and are to be ignored in the interpretation of this Agreement. 
 SECTION TWO

 PURPOSE OF THE COMPANY AND SCOPE OF THIS AGREEMENT 

2.1     Purpose of the Company. 

The Company’s purpose is to (i) acquire an ownership interest in certain sugar and ethanol assets in Brazil and convert a portion of the
production capacity of such assets to the production of 

 Execution Version 

 

 
Amyris Renewable Products, and (ii) provide other Brazilian sugar and ethanol mills with access to the Amyris Technology for the production of Amyris Renewable Products. 

2.2       Scope of this Agreement. 

The scope of this Agreement is to establish the terms and conditions that shall rule the relationship of the Shareholders of the Company, including:
(i) management and corporate governance of the Company, (ii) voting rights, (iii) conditions applicable to the Transfer of Shares, and (iv) a possible IPO of the Company. 

2.2.1    Capital ownership 

For future reference regarding the capital ownership of the Company, parties should refer to the copy of the Company’s share
registry book as of this date, which is attached to this Agreement as Exhibit I. 
 SECTION THREE 

SHAREHOLDERS’ MEETING 

3.1       Shareholders Meetings. 

Annual Shareholders’ Meetings shall take place in the head offices of the Company, within four (4) months following the end of each fiscal
year, and extraordinary Shareholders’ Meetings may take place whenever called by any member of the Board of Directors or in accordance with article 123 of the Brazilian Corporation Law. 

3.2       Shares Representation. 

Each Share shall represent 1 (one) vote at any Shareholders’ Meeting and the Shareholders agree not to adopt multiple vote provisions under article
141 of the Brazilian Corporation Law. Except as may be otherwise expressly stated herein, in the Company’s by-laws, in the Brazilian Corporation Law or in any other applicable laws, resolutions passed at any Shareholders’ Meeting shall
require the approval of the Shareholders holding a simple majority of the Shares authorized and entitled to vote. 

3.3       Matters Subject to the Shareholders’ Meeting. 

Subject to section 3.4 below, the following matters shall be decided by the Shareholders in a Shareholders’ Meeting, without prejudice to other
matters attributed to the Shareholders’ Meeting by the Brazilian Corporation Law: 
  

	(i)	amendment to the by-laws of the Company; 

  

	(ii)	any capital increase and the issuance of new shares by the Company, whenever such capital increase is greater than the authorized capital (capital autorizado)
set forth in the Company’s by-laws and the price per share is equal to or greater than the price paid by Stratus on
December 22nd, 2009, as well as issuance of other
securities; 

 Execution Version 

 

	(iii)	any capital reduction of the Company; 

  

	(iv)	election of the members of the Board of Directors of the Company, with due regard to the provisions set forth in section 4.1 below; 

 

	(v)	approval of bonus, stock option or similar plans or schemes for the employees and managers of the Company, and any amendment of the foregoing, with due regard to
section 4.7 below; 

  

	(vi)	approval of any dividend policy and any amendments to the foregoing; 

  

	(vii)	specific approval of the distribution of dividends in a given year by the Company, in accordance with the applicable dividend policy; and 

 

	(viii)	decision to carry out the IPO, with due regard to the provisions set forth in section 6.1 below. 

3.4     Supermajority Approvals. 

The following matters shall be decided in a Shareholders’ Meeting by Shareholders holding at least 85% (eighty-five per cent) of the total corporate
capital of the Company: 
  

	(i)	dissolution or liquidation of the Company; 

  

	(ii)	merger, transformation, amalgamation or spin-off of the Company; 

  

	(iii)	request for bankruptcy, as well as for judicial or non-judicial recovery (recuperação judicial ou extrajudicial); and 

 

	(iv)	any capital increase and the issuance of new shares by the Company, whenever such capital increase is greater than the authorized capital (capital autorizado)
set forth in the Company’s by-laws and the price per share is lower than the price paid by Stratus on
December 22nd, 2009. 

3.5.    Authorized Capital. 

The Shareholders agree that they shall not amend the bylaws of the Company to exclude or reduce the amount of the Company’s authorized corporate
capital established on December 22nd, 2009.

 SECTION FOUR 

MANAGEMENT 

4.1     Management. 

The management of the Company shall be carried out by the Board of Directors and the Board of Officers in accordance with the provisions set forth in
this Section Four. 

 Execution Version 

 

 4.2      Board of Directors. 

The Board of Directors shall be responsible for the supervision of the management of the Company, for strategic and policy decisions, and other tasks and
matters allotted to the Board of Directors by the laws of Brazil, this Agreement and the by-laws of the Company. 

4.3      Election of the Board of Directors. 

The Board of Directors shall consist of 5 (five) directors appointed as follows: (i) ABI shall be entitled to appoint 3 (three) directors;
(ii) the Investors shall be entitled to appoint 1 (one) director as long as the amount of Investors’ cash contribution into the Company corresponds to at least 10% (ten per cent) of the sum of the Total Contribution Amount and all future
contributions made into the Company, provided that all Investors shall vote as block to elect such director; and (iii) 1 (one) independent director, with substantial experience in the Brazilian sugar and ethanol sector, shall be
unanimously appointed by the other directors. The Shareholders’ undertake to approve the election of the directors appointed in accordance with the conditions established in this section, for a term of office of 2 (two) years, being re-election
permitted. 
 4.3.1     Resignation of the Director Appointed by the Investors. 

Whenever the amount of the Investors’ cash contribution into the Company falls below 10% (ten per cent) of the sum of the Total
Contribution Amount and all future contributions made into the Company, the Board of Directors may require the resignation of the director appointed by it, in which case the Board of Directors will consist of 4 (four) directors after the
resignation. 
 4.3.2     Observer Seat at the Board of Directors. 

4.3.2.1 Stratus. 

Whenever Stratus is not able to elect a member of the Board of Directors, it shall be entitled to 1 (one) non-voting observer at the
Board of Directors. 
 4.3.2.2 Red Mountain. 

As long as Red Mountain is a Shareholder of the Company, it shall be entitled to 1 (one) non-voting observer at the Board of Directors.

 4.4      Matters Subject to the Board of Directors. 

The matters below shall be subject to the approval of the simple majority of the members of the Board of Directors: 

 

	(i)	any capital increase and the issuance of new shares by the Company, whenever such capital increase is lower than or equal to the authorized capital (capital
autorizado) set forth in the Company’s by-laws and the price per share is equal to or greater than the price paid by Stratus on
December 22nd, 2009; 

 Execution Version 

 

	(ii)	the sale or disposal of any assets of the Company in an amount of over R$ 250,000 (two hundred and fifty thousand Brazilian Reais); 

 

	(iii)	the assumption of any obligations by the Company in an amount of over R$ 1,000,000 (one million Brazilian Reais), except for any obligation that requires the unanimous
consent of the Board of Directors pursuant to section 4.4.1 below; 

  

	(iv)	approval of the Company’s Business Plan and Budget; 

  

	(v)	creation of Encumbrances over the Company’s assets that are not provided for in the annual budget; 

 

	(vi)	appointment and replacement of the officers of the Company, with due regard to section 4.6 below; 

 

	(vii)	approval of the policies of the Company (finance and investments, people and organization, insurance, legal affairs etc.); 

 

	(viii)	approval of material commercial and operational decisions related to the use of the Amyris Technology; 

 

	(ix)	any Related Party Transaction; and 

  

	(x)	approval of any contract entered into by AB related to the use of the Amyris Technology or the manufacture, marketing, sale or distribution of Amyris Renewable
Products, and/or any other products or services made through the use of Amyris Technology or otherwise in connection with the rights granted under the Technology License. 

4.4.1     Matters Subject to the Unanimous Approval of the Board of Directors. 

The matters below shall be subject to the approval of all of the members of the Board of Directors: 

 

	 	(i)	any capital increase and the issuance of new shares by the Company, whenever such capital increase is lower than or equal to the authorized capital (capital
autorizado) set forth in the Company’s by-laws and the price per share is lower than the price paid by Stratus on
December 22nd, 2009; 

 

	 	(ii)	the contracting of loans or the entering into other financial obligations by the Company in an amount that exceeds, individually or in the aggregate in any period of 12
(twelve) months, 100% of the Company’s paid in equity; 

  

	 	(iii)	any sale or Transfer of assets by the Company in an amount that exceeds, individually or in the aggregate in any period of 12 (twelve) months, 15% (fifteen percent) of
the Company’s paid in equity; 

 Execution Version 

 

	 	(iv)	replacement of the auditors of the Company for auditors that are not within the “Big Four” accounting firms (namely PricewaterhouseCoopers, KPMG, Deloitte and
Ernst & Young and their respective successors in title); and 

  

	 	(v)	termination of the Technology License. 

4.5      Board of Officers. 

The initial Board of Officers shall consist of either one Chief Executive Officer (“CEO”) or one officer superintendent (Diretor
Superintendente), one Financial Officer (Diretor Financeiro) and such additional senior management as may be necessary. The Board of Officers shall be responsible for routine management of the activities of the Company. The members of the
Board of Officers shall perform their duties in accordance with applicable laws, the by-laws of the Company, and any internal guidelines of the Company (including instructions given by the Board of Directors). The Board of Directors may alter the
composition of the Board of Officers from time to time by majority vote. 
 4.6      Election of the Board of
Officers. 
 The CEO and the Financial Officer must be approved by the unanimous vote of the Board of Directors, while the other members of
the Board of Officers must be approved by the majority of the Board of Directors. 
 4.7      Management
Incentive Program. 
 The Shareholders’ Meeting shall approve an equity incentive plan of up to 5% of the fully diluted equity of the
Company, if there is any dilution, to be set forth in the Company’s by-laws, consisting of options to purchase Shares of the Company to be issued through a capital increase within the Company’s authorized capital (capital
autorizado) or other type of incentive plans as proposed by the Board of Directors. In the event Shares are issued and acquired by the Company’s managers under an incentive plan, such Shares shall be subject to the conversion rights and
obligations set forth in Section Seven hereof. 
 4.8      D&O Insurance. 

The Shareholders shall cause the Company to contract D&O insurance for all of the members of the Board of Directors and of the Board of Officers, in
accordance with market terms. 
 SECTION FIVE 

TRANSFER OF SHARES 

5.1      General Restriction and Lock-Up Periods. 

 

	(a)	 Except for Transfer of Shares by Shareholders to any of its Affiliates, no Shareholder may Transfer any Shares issued by the Company, except in
accordance with the provisions of this Section Five. Any attempt by a Shareholder to Transfer any of its Shares without compliance with this Agreement shall be null and void ab initio, and the Company shall not give any effect to such attempted
Transfer in its books and records. 

 Execution Version 

 

	 	 
The transferee of any Shares Transferred by a Shareholder in violation of this Agreement shall not be entitled to (i) any right, title and interest in or to such Shares, (ii) any rights
to vote such Shares, or (iii) any distributions in respect thereof. 

  

	(b)	Transfer at any time of Shares of the Investors to funds, vehicles or investment accounts managed by SGC or SIL shall be allowed at any time, as long as there is no
change of the final beneficiary of such Investors. 

  

	(c)	Conversion of Shares of the Investors into shares of ABI pursuant to Section Seven shall be allowed at any time. 

 

	(d)	For the avoidance of doubt, a Change of Control Event of ABI shall not be considered a Transfer of AB’s Shares. 

 

	(e)	From
December 22nd, 2009 and until 18 (eighteen) months
after the Closing, no Shareholder shall be permitted to Transfer its Shares to any third party. Additionally, until June 30, 2013, the Investors shall not be permitted to Transfer their Shares to an AB Competitor, unless the Company becomes
publicly listed and traded in Brazil during that period, in which case such restriction shall not apply with respect to any Off-Exchange Sales that are not Block Sales. 

5.2      Preemptive Rights. 

The Shareholders will have preemptive rights to purchase any equity or convertible debt security issued and offered by the Company from time to time so
as to maintain their pro rata ownership in the Company, in accordance with article 171 of the Brazilian Corporation Law, except for cases of issuance of shares by the Company under a management stock option plan, being certain that the
Shareholders may transfer such rights to Affiliates or vehicles under common control, subject to the transfer restrictions set forth in this Agreement. 

5.3      Right of First Refusal for Acquisition of the Investors’ Shares. 

If any Investor wishes, directly or indirectly, to Transfer some or all of its Shares (the “Investor Offered Shares”), it must offer
such Investor Offered Shares to ABI in accordance with the following provisions: 
  

	(a)	The Investor shall deliver a notice (“ABI Offer Notice”) to ABI stating (i) its bona fide intention to offer such Investor Offered Shares,
(ii) the number of such Investor Offered Shares to be offered, (iii) the price and terms, if any, upon which it proposes to offer such Investor Offered Shares, and (iv) when applicable, the identity of any third party who has offered
to buy such Investor Offered Shares and a copy of the offer received from such third party, as long as ABI accepts in writing to be subject to the confidentiality requirements established by the Investor and the third party.

  

	(b)	 The Investor’s offer shall remain effective for acceptance by ABI for a period of 30 (thirty) days, as of the date of receipt of the Offer Notice,
unless earlier waived by AIM (the “ABI Acceptance Period”). During the ABI Acceptance Period, ABI shall have the right to accept all, but not less than all of the Investor Offered Shares, by giving written

 Execution Version 

 

	 	 
notice to the Investor who wishes to sell its Shares. The failure by ABI to reply to the ABI Offer Notice within the ABI Acceptance Period shall be deemed as the non-exercise of its right of
first refusal. 

  

	(c)	If ABI does not exercise its right of first refusal, the Investor shall have the right, exercisable not later than 90 (ninety) days following the expiration of the ABI
Acceptance Period, to consummate the Transfer of the Investor Offered Shares to a third party on the same terms and conditions of the offer presented to ABI in the ABI Offer Notice. If the Investor does not consummate such Transfer within such 90
(ninety) day period, the Investor Offered Shares shall again be subject to the terms, conditions and restrictions set forth in this section 5.3. 

5.4      Right of First Refusal for Acquisition of ABI’s Shares. 

If ABI wishes, directly or indirectly, to Transfer some or all of its Shares (the “ABI Offered Shares”), it must offer such ABI Offered
Shares to the Investors in accordance with the following provisions: 
  

	(a)	ABI shall deliver a notice (“Investors Offer Notice”) to the Investors stating (i) its bona fide intention to offer such ABI Offered Shares,
(ii) the number of such ABI Offered Shares to be offered, and (iii) the price and terms, if any, upon which it proposes to offer such ABI Offered Shares and (iv) when applicable, the identity of any third party who has offered to buy
such ABI Offered Shares and a copy of the offer received from such third party, as long as the Investors accept in writing to be subject to the confidentiality requirements established by ABI and the third party. 

 

	(b)	ABI’s offer shall remain effective for acceptance by the Investors for a period of 30 (thirty) days, as of the date of receipt of the Investors Offer Notice,
unless earlier waived by the Investors and subject to the additional term provided for in section 5.4(d), if applicable, (the “Investors Acceptance Period”). During the Investors Acceptance Period, the Investors shall have the right
to accept all, but not less than all of the ABI Offered Shares, by giving written notice to ABI. The failure by the Investors to reply to the Investors Offer Notice within the Investors Acceptance Period shall be deemed as the non-exercise of the
right of first refusal by the Investors. 

  

	(c)	If the Investors do not exercise their right of first refusal, ABI shall have the right, exercisable not later than ninety (90) days following the expiration of
the Investors Acceptance Period, to consummate the Transfer of the ABI Offered Shares to a third party on the same terms and conditions of the offer presented to the Investors in the Investors Offer Notice. If ABI does not consummate such Transfer
within the mentioned ninety (90) day period, the ABI Offered Shares shall again be subject to the terms, conditions and restrictions set forth in this section 5.4. 

 

	(d)	 Each Investor shall have the right to accept to acquire a number of the ABI Offered Shares proportional to their equity participation in the Company.
If one or more Investors accept to acquire their pro rata share of the ABI Offered Shares (the “Accepting Investors”), but one or more Investors refuse to acquire such Shares, then the Accepting

 Execution Version 

 

	 	 
Investors shall have the right to acquire the refused part of the ABI Offered Shares, also on a pro rata basis, according to their equity participation in the Company. The Accepting Investors
shall have additional 15 (fifteen) days to accept to acquire all remaining ABI Offered Shares. The failure by the Accepting Investors to accept all, but not less than all remaining ABI Offered Shares within such additional period shall be deemed as
the non-exercise of all Investors’ right of first refusal under this section 5.4. 

5.5      Tag Along Rights. 

If, subject to the provisions of sections 5.3 or 5.4 above, ABI decides to Transfer the Control of the Company to a third party, other than to an
Affiliate and in a way that ABI ceases to hold the direct or indirect Control of the Company, in one transaction or in a series of transactions (whether related or not), by contract or otherwise, each of the Investors shall have the right to sell
all of its Shares to the same third party, together with the Shares Transferred by ABI, at the same terms, conditions, price and form of payment (“Tag Along Right”), according to the following procedure: 

 

	(a)	ABI shall present to the Investors a notice, which shall include the identity of the acquiring third party, the proposed sale price per Share and any other terms and
conditions of the intended Transfer, including a copy of the offer received by ABI, when applicable (“Tag Along Notice”). 

  

	(b)	Each of the Investors shall have the right to exercise its Tag Along Right during a period of 30 (thirty) days, as of the date of receipt of the Tag Along Notice, by
giving written notice to the transferring Shareholder, being the failure of doing so interpreted as non-exercise of such right. 

5.6      Drag Along Rights. 

If, subject to the provisions of section 5.4 above and section 5.8 below, ABI decides to Transfer all of its Shares to any third party, ABI may compel
all the Investors to sell all of their Shares to the same third party, together with the Shares Transferred by ABI, at the same terms, conditions, price and form of payment. ABI shall provide the identity of any third party who has offered to buy
its Shares and a copy of the offer received from such third party, as long as the Investors accept in writing to be subject to the confidentiality requirements established by ABI and the third party. 

For ABI to be able to exercise the Drag Along Rights provided for in this section, the price to be paid to each of the Investors for the Shares to be
transferred upon such exercise may not be lower than their pro rata share of the Put Option Price provided for on section 5.8, The Change of Put Option Price provided for on section 5.8.1 shall also be applicable in case of exercise of Drag Along
Rights under this section. 
 5.7      Adhesion to this Agreement. 

No Transfer of Shares shall be allowed if the potential transferee refuses to adhere fully to this Agreement. 

 Execution Version 

 

 5.8      Change of Control of AB. 

If the Company undergoes a Change of Control Event in which the Investors’ pro rata share of the Acquisition Price is lower than the Minimum
Investors’ Return, each Investor will have a put option against ABI. Such put option will be exercisable within 10 (ten) days, as of the receipt by the Investors of a notice sent by ABI informing that it has received a binding offer from one or
more third parties willing to acquire the control of AB through a Change of Control Event (the “Third Party Acquirer”), and will entitle the Investors to sell all their Shares to ABI, for a total amount equal to the Put Option
Price. Each of the Investors shall have the right to receive from ABI its pro rata share of the total Put Option Price, in accordance with its respective equity participation in AB determined as of the date the put option is exercised. The Put
Option Price shall be paid by ABI to each Investor within 5 (five) business days of receipt by ABI of the effective payment, made by the Third Party Acquirer or by AB, of the sale proceeds arising from said Change of Control Event. 

5.8.1    Change of Put Option Price. 

In the event AB is valued at the Minimum Future AB Pre-Money Valuation in connection with a Change of Control Event or an IPO of AB, the
price of the put option held by the Investors, in the situation described in this section 5.8, shall be the lower of (i) the amount invested by the Investors in AB in Brazilian Reais; and (ii) the total amount of proceeds actually received
by ABI from a third party acquirer or from AB, in connection with a Change of Control Event relating to the Company. 

SECTION SIX 

INITIAL PUBLIC OFFERING OF AB 

6.1      Approval of the IPO. 

The Shareholders hereby commit to vote in a Shareholders’ Meeting in order to approve an IPO of the Company, after 4 (four) years of the Closing, as
long as market conditions are favourable for an IPO, as determined by an internationally recognized investment bank to be selected by the Board of Directors. 

6.2      Lock-Up after the IPO. 

The Shareholders undertake to comply with written any recommendations of the investment bank coordinating the IPO relating to restrictions on Transfer of
shares during a certain period following the IPO, such recommendations aimed at maximizing the shares’ price at the IPO, provided, however, that following such period, the Investors shall be immediately released from the lock-up established
under section 5.1 above. 
 6.3      Secondary Offers by the Shareholders. 

In the event the investment bank coordinating the IPO recommends that the IPO may include the offer of shares held by the shareholders (secondary
offering), each of the Investors shall have the right to participate of such secondary offering, through the public offer of their Shares jointly with the Company’s primary offer at the time of the IPO, pro rata to their then stock ownership.

 Execution Version 

 

 SECTION SEVEN 

EFFECTS OF ABI CHANGE OF CONTROL EVENT AND ABI IPO 

7.1      ABI Change of Control Event. 

Subject to the restrictions on the transfer of the Shares set forth in Section Five above, if ABI undergoes a Change of Control Event, the following
provisions shall apply: 
  

	(i)	Each of the Investors shall have the right to convert all, and not less than all of its Shares in AB to shares of ABI common stock at the Conversion Ratio by providing
written notice to ABI of its desire to carry out the conversion within ten (10) business days of receipt of a written notice by ABI, explaining the general terms of the transaction underlying the Change of Control Event, the identification of
the potential acquirer(s), the expected closing date and the consideration to be provided for the acquisition of Control in AB (“ABI Change of Control Notice”); 

 

	(ii)	In the case described in item “i” above, the Investors shall become shareholders of ABI after the conversion and before the Change of Control Event and will
be able to sell their equity interest in ABI under the same conditions granted to other common stock holders of ABI within the Change of Control Event. 

7.2      ABI IPO. 

Subject to the restrictions on the transfer of AB’s Shares set forth in Section Five above, in the event of an ABI IPO, each of the Investors shall
have the following rights: 
  

	(i)	The right to exchange some or all of its Shares in AB for restricted shares of ABI common stock at the Conversion Ratio, by providing written notice to ABI of its
desire to carry out the conversion, such notice to be delivered within ten (10) business days of receipt of a written notice informing the Investors about the ABI IPO which will be issued by ABI promptly after the relevant underwriter is chosen
and a registration statement is filed with the United States Securities Exchange Commission, being certain that any such notice by the Investors shall be binding upon them after delivery, and that once the conversion is completed the Investors shall
be subject to the lock-up requirements and any plan of sale requirements imposed by the underwriters of ABI. Notwithstanding the foregoing, the Investors acknowledge and agree that the shares of ABI to be received pursuant to this section 7.2(i)
shall not be registered as secondary shares in the ABI IPO unless and to the extent determined by ABI in consultation with the relevant underwriter and as allowed by all applicable laws. In the event that the finance liquidation of the IPO does not
occur for any reason within 12 (twelve) months as of the delivery of the notice mentioned above by the Investors to ABI, the Investors shall have the right to cancel the exchange of the applicable Shares for registered shares of ABI and to receive
back its Shares issued by AB, at ABI’s expense, and the Parties hereby agree to take all measures necessary or required in order to implement the foregoing; and 

 

	(ii)	Notwithstanding the foregoing, in the event the Parties and ABI’s Board of Directors agree to convert ABI’s investment in AB into BDRs, the Investors shall
have the right to convert their AB Shares into ABI BDRs at the Conversion Ratio after the completion of an ABI IPO. 

 Execution Version 

 

 7.3.      ABI’s Call for Conversion. 

ABI shall have the right to require the Investors to exchange some or all of their Shares in AB for restricted shares of ABI common stock, at the
Conversion Ratio, in the event ABI is valued at least U.S.$ 500,000,000 (five hundred million United States dollars) in connection with an ABI IPO or an ABI Change of Control Event. In that case, ABI shall provide written notice to the Investors of
its desire to carry out the conversion no later than ten (10) days prior to the closing of the transaction in connection with which the conversion is being required (the “ABI Conversion Notice”). The conversion will be effective
immediately prior to the closing of the relevant transaction. The Investors shall (i) enter into the applicable agreement for effecting the conversion (in reasonable form provided by ABI), (ii) in the event the triggering transaction is an
ABI IPO, enter into any lock-up agreement and/or plan of sale documents required by the underwriters, and (iii) enter into and deliver such other documents as are necessary to cause the relevant transaction to be completed. The Investors
further agree to provide such information as may be requested by ABI to ensure compliance with all applicable laws, including securities laws. Each Party agrees to take such further actions as are necessary to cause the conversion of shares to be
consummated. 
  

	 	7.3.1	Each Party agrees to use reasonable efforts to cause the conversion of shares to be consummated in such a way that would maximize benefits for each of the
Parties. 

  

	 	7.3.2	In the event the conversion required under this section 7.3, cannot be carried out due to regulatory restrictions applicable to ABI or one of the Investors, the
parties shall use reasonable efforts to agree on a mechanism, within 30 (thirty) days of receipt of the ABI Conversion Notice, by which the Investors would (i) cease to be shareholders of AB; and reach the same economic results as if they had
converted their Shares into shares of ABI as provided herein. In any case, no regulatory restriction applicable to the Investors, nor the failure of any of the Investors to comply with any obligation provided for in the Agreement, especially those
provided for in this Section 7.3 shall prevent ABI from exercising the right set forth in this section. 

SECTION EIGHT 

RIGHT TO CONVERT INTO ABI STOCK 

8.1.      Right to Convert into ABI stock 

 

	(i)	In case, by December 31, 2012, any of the Investors who remain as Shareholders of AB, having not converted their shares in AB to shares of ABI common stock
pursuant to Section 7.1 in connection with a Change of Control of ABI, or pursuant to Section 7.2 or Section 7.3 in connection with an ABI IPO, such Investor will have the right to convert its Shares of AB into shares of ABI common
stock, at the Conversion Ratio, subject to compliance by ABI and the Investors with all applicable laws (including securities laws). 

 Execution Version 

 

	(ii)	The Investors will have fifteen (15) days from the abovementioned date to provide ABI with notice of their intention to convert their Shares of AB into shares of
ABI common stock. ABI shall endeavor to use reasonable efforts to carry out the exchange of shares within ninety (90) days after the deadline provided for in this paragraph has elapsed. 

8.2      The Parties agree that the right of the Investors to convert their Shares of into shares of ABI common
stock, provided for in section 8.1 above, is fully conditioned and inherent to the fact that they are (i) shareholders of AB and (ii) part of this Agreement, so that this right, as well as any other rights or obligations arising out of
this Agreement may not be transferred to any third party without the Parties’ prior consent. Any assignment of rights in disregard with this provision shall be rendered null and void. 

SECTION NINE 

INFORMATION RIGHTS 

9.1.     Information Rights. 

The following information rights shall apply to AB and to the Investors. 

 

	(i)	The right to receive AB’s annual unaudited financial statements before March 15th of the subsequent year and audited financials as soon as they are available;

  

	(ii)	Forty-five (45) days after the end of each of the first three (3) quarters of each fiscal year of the Company, the right to request and receive financial and
operational reports relating to a certain month; 

  

	(iii)	At each Party’s own expense, upon reasonable advanced notice and during normal business hours: (A) the right to inspect AB’s facilities; (B) the
right to inspect AB’s books and records; and (C) reasonable access rights to members of AB’s management team. 

SECTION TEN 

CORPORATE GOVERNANCE STANDARDS 

10.1     Corporate Governance Standards. 

The Company and its management shall follow the best practices of corporate governance, following the requirement of Bovespa Mais, including in relation
to transparency and reporting, and shall adopt the following practices: 
  

	(i)	During the first year following December 22nd, 2009, the Company shall hold at least ten meetings of the Board of Directors per year; 

 

	(ii)	After the period mentioned in “i” above, if approved by an unanimous vote of the Board of Directors, the Company shall hold at least quarterly meetings of the
Board of Directors per year; 

 Execution Version 

 

	(iii)	The agenda with matters to be discussed in meetings of the Board of Directors shall be distributed to its member with 8 (eight) days in advance;

  

	(iv)	The meetings of the Board of Directors may be carried out through videoconference or teleconference; 

 

	(v)	Monthly the management of the Company shall inform the Shareholders about revenues, cash and debt position on a monthly basis. 

SECTION ELEVEN 

SPECIFIC PERFORMANCE 

11.1    Specific Performance. 

The Shareholders agree that the obligations imposed on them in this Agreement are special, unique and of an extraordinary character, and that, in the
event of breach by any Shareholder, damages would not be an adequate remedy and, therefore, each of the other Shareholders shall be entitled to specific performance and injunctive relief, in addition to any other remedy to which it may be entitled,
by law or in equity; and the Shareholders further agree to waive any requirement for the securing or posting of any bond in connection with the obtaining of any such injunctive or other equitable relief. The Shareholders agree that all of the
obligations undertaken by them hereunder are subject to, and shall enjoy the benefit of specific performance in accordance with Articles 461, 466-A and 466-B of the Brazilian Civil Procedure Code. 

SECTION TWELVE 

GENERAL PROVISIONS 

12.1    Entire Agreement. 

This Agreement shall constitute the entire agreement between the Parties hereto and supersede and replace all other agreements and understandings, verbal
or written, among the Parties with respect to the subject matter of this Agreement. No amendment or modification of any provision of this Agreement shall be effective unless it is done in writing and signed by each of the Parties. 

12.2    Severability. 

The invalidity of one or more provisions of this Agreement shall not affect the validity of this Agreement as a whole unless the invalid provision was of
such essential importance to this Agreement that it is to be reasonably assumed that the Parties would not have entered into this Agreement without such invalid provision. The Parties shall negotiate in good faith to substitute any invalid
provisions with other provisions that may substantially achieve their original intentions. 
 12.3    Waiver.

 Any term or condition of this Agreement may be waived at any time by the Party that is entitled to the benefit thereof, but no such
waiver shall be effective unless set forth in a written instrument duly executed by or on behalf of the Party waiving such term or condition. The 

 Execution Version 

 

 
failure of any Party at any time to enforce any provision of this Agreement shall not in any way affect its rights to require performance thereof, nor shall the waiver of any breach of any
provision hereof be taken or held to be a waiver of any succeeding breach of any such provision or as a waiver or a novation (novação) of the provision itself. 

12.4    Assignment. 

No Party may directly or indirectly transfer any of its rights and obligations under this Agreement to any third party, without the prior written consent
of the other Party, except that (i) any person may acquire the Shares in compliance with the provisions of Section Five hereto, and then adhere to this Agreement, and (ii) that Stratus may transfer any of its rights and obligations under
this Agreement to any of its Affiliates without the need of prior written consent of the other Parties. 
 12.5    Costs
and Expenses. 
 Each Party shall bear all costs and expenses incurred by it in connection with the preparation, negotiation and delivery of
this Agreement. However, AB shall either pay directly or reimburse the Investors and ABI (the latter at ABI’s own election) for reasonable transaction-related expenses, not to exceed R$ 250,000 (two hundred and fifty thousand Brazilian Reais)
for each of ABI and the Investors. In the case of ABI, reasonable transaction related expenses shall be deemed to include any IOF or similar taxes associated with the ABI Cash Contribution. 

12.6    Notices. 

All notices, requests, claims and other communications hereunder shall be in writing and communicated to the receiving party either by hand, or sent by
registered mail, electronic mail or facsimile and addressed as follows or to such other addresses as may from time to time be notified by any Party to the other Party: 

If to ABI: 
 AMYRIS BIOTECHNOLOGIES, INC.

 Address: 5885 Hollis Street, Suite 100, Emeryville, California 94608, USA 

Telephone: +1 510 740-7416 
 Fax: +1 510 842 1460

 E-mail: tompkins@amyris.com
 Attn:
Tamara Tompkins - General Counsel 
 If to Stratus: 

FUNDO MÚTUO DE INVESTIMENTO EM EMPRESAS EMERGENTES INOVADORAS 

STRATUS GC III 
 Address: Rua Funchal, 129, 13
th floor, São Paulo, SP, Brazil 

Telephone: +55 11 2166-8800 
 Fax: +55 11
2166-8801 
 E-mail: acamoes@stratusbr.com 

Attn: Alberto Camões 

 Execution Version 

 

 Copy to: 

MACHADO, MEYER, SENDACZ E OPICE ADVOGADOS 

Address: Avenida Brigadeiro Faria Lima, 3144,
11th floor 

Telephone: +55 11 3150-7647 
 Fax: +55 11
3150-7071 
 E-mail: mau@mmso.com.br 

Attn.: Mauro Cesar Leschziner 
 If to AB:

 AMYRIS BRASIL S.A. 
 Address: Rua
James Clerk Maxwell, 315, Campinas, SP, Brazil 
 Telephone: +55 19 3783-9450 

Fax: +55 19 3283-0005 
 E-mail:
collier@amyris.com 
 Attn: Roel Collier 

If to Red Mountain: 
 PEDRO PAULO
FALLEIROS DOS SANTOS DINIZ 
 Address: Rua Jerônimo da Veiga, 384,
3rd floor 

Telephone: +55 11 3705-5161 
 Fax: + 55 11
3702-5112 
 E-mail: pedro@ppdholding.com 

Copy to: 
 KLA- KOURY LOPES ADVOGADOS

 Address: Avenida Brigadeiro Faria Lima, 1355,
18th floor 

Telephone: +55 11 3799-8118 
 Fax: +55 11
3799-8200 
 E-mail: mcortez@klalaw.com.br 

Attn.: Mariana Machado Cortez 

12.6.1  Delivery of Notice. 

Any notice served by hand shall be deemed to have been served upon delivery. Any notice served by prepaid registered mail shall be deemed
to have been served upon evidenced receipt. Any notice served by e-mail or facsimile shall be deemed to have been served when sent, provided that evidence has been produced showing that the notice has been sent to the facsimile number/e-mail
address, as indicated in this Agreement. 
 12.6.2  Change of Data. 

In case of any change of data, if the new information is not notified by the relevant Party to the other Party, all notices sent to the
previous addresses shall be deemed to have been duly served. 

 Execution Version 

 

 12.7    Language. 

This Agreement shall be executed in the English and Portuguese languages, provided that the English version shall prevail, including in arbitration, and
excluding when in proceedings before Brazilian courts, in which the Portuguese version shall prevail. 
 SECTION THIRTEEN 

 GOVERNING LAW AND DISPUTE RESOLUTION 

13.1    Governing Law. 

This Agreement shall be governed by and construed in accordance with the laws of Brazil. 

13.2    Dispute Resolution. 

Any dispute, controversy or claim by and among the Parties to this Agreement, arising out of or relating to this Agreement, or the breach, termination or
validity hereof, shall be settled by arbitration in accordance with the Rules of Arbitration of the Câmara de Comércio Brasil-Canadá (the “Rules of Arbitration”). The decision of the arbitrators shall be final
and binding upon the Parties with no further appeal, recourse or review. Until such decision, the Parties agree to keep the arbitration procedure on a confidential basis, except to the extent necessary for any interim or conservatory measures
permitted under the Rules of Arbitration. 
 13.2.1  Arbitration Place. 

The place of arbitration shall be in the City of São Paulo, State of São Paulo, Brazil, where the arbitration award shall
be rendered. 
 13.2.2  Arbitration Language. 

The language of the arbitration shall be English. 

13.2.3  Judicial Measures. 

Without prejudice to this section 13.2 and without limiting any other powers the arbitrators may have, the Parties remain fully entitled
to request judicial measures: (a) in order to obtain preliminary and urgent measures (medidas cautelares) prior to the formation of the arbitral tribunal, and such judicial recourse shall not be interpreted as a waiver of the arbitration
as set forth in this section; and (b) to enforce any arbitral decision, including the final award. For that purpose, the Parties elect the courts of the city of São Paulo, State of São Paulo, Brazil, being waived any other no
matter how privileged it may be. The Parties recognize that any provisional or urgent matter granted by judicial courts shall be, necessarily, reviewed by the arbitral tribunal, which shall decide on its ratification, revision or cancellation.”

 12.      Language. This Amendment shall be executed in the English and Portuguese languages, provided
that the English version shall prevail, including in arbitration, and excluding when in proceedings before Brazilian courts, in which the Portuguese version shall prevail. 

 Execution Version 

 

 In witness whereof, this Amendment is executed in 5 (five) counterparts of the same form and content, in
the City of São Paulo, State of São Paulo, Brazil, on May 26, 2010. 
 PARTIES: 

 

	
	
	    /s/ [illegible]
	RED MOUNTAIN JET LLC
	
	    /s/ [illegible]
	FUNDO MÚTUO DE INVESTIMENTO EM EMPRESAS EMERGENTES
INOVADORAS STRATUS GC III BY ITS MANAGER STRATUS GESTÃO DE CARTIEIRAS
LTDA.
	
	    /s/ [illegible]
	AMYRIS BIOTECHNOLOGIES, INC.
	
	    /s/ [illegible]
	AMYRIS BRASIL S.A.
	
	    /s/ [illegible]
	STRATUS INVESTIMENTOS LTDA.

WITNESSES: 
  

									
	1.	 	    /s/ Luana Komatsu	  		  	2.	  	    /s/ Gabriel Aldallah Mundim
	 Name: Luana YoKo Vieira Komatsu
	  		  	 Name: Gabriel Aldallah Mundim

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