Document:

Confirmation for additional warrant transaction

 Exhibit 10.8 
 GOLDMAN, SACHS & CO. | 200 WEST STREET | NEW YORK, NEW YORK 10282-2198 |TEL: (212) 902-1000 
 June 24, 2011 
  

			
	 To:
	 	NuVasive, Inc.
		 	7475 Lusk Blvd
		 	San Diego, CA 92121
	 Attention:
	 	Chief Financial Officer
	 Telephone No.:
	 	858-909-1800
	 Facsimile No.:
	 	858-909-2000

 Re: Additional Warrants (Reference No.
SDB4165059085) 
 The purpose of this letter agreement (this “Confirmation”) is to confirm the terms and
conditions of the Warrants issued by NuVasive, Inc. (“Company”) to Goldman, Sachs & Co. (“Bank”) on the Trade Date specified below (the “Transaction”). This letter agreement constitutes a
“Confirmation” as referred to in the ISDA Master Agreement specified below. This Confirmation shall replace any previous agreements and serve as the final documentation for this Transaction. 

The definitions and provisions contained in the 2002 ISDA Equity Derivatives Definitions (the “Equity Definitions”), as
published by the International Swaps and Derivatives Association, Inc. (“ISDA”), are incorporated into this Confirmation. In the event of any inconsistency between the Equity Definitions and this Confirmation, this Confirmation
shall govern. The Transaction shall be a Warrant Transaction, which shall be considered a Share Option Transaction within the meaning set forth in, and for purposes of, the Equity Definitions. 

Each party is hereby advised, and each such party acknowledges, that the other party has engaged in, or refrained from engaging in,
substantial financial transactions and has taken other material actions in reliance upon the parties’ entry into the Transaction to which this Confirmation relates on the terms and conditions set forth below. 

1. This Confirmation evidences a complete and binding agreement between Bank and Company as to the terms of the Transaction to which this Confirmation
relates. This Confirmation shall supplement, form a part of, and be subject to an agreement in the form of the 2002 ISDA Master Agreement (the “Agreement”) as if Bank and Company had executed an agreement in such form (but without
any Schedule except for the election of the laws of the State of New York as the governing law) on the Trade Date. In the event of any inconsistency between provisions of that Agreement and this Confirmation, this Confirmation will prevail for the
purpose of the Transaction to which this Confirmation relates. The parties hereby agree that no Transaction other than the Transaction to which this Confirmation relates shall be governed by the Agreement. For the avoidance of doubt, the Transaction
shall not constitute a “Transaction” as defined in any ISDA Master Agreement currently existing or entered into from time to time between Bank and Company. 
 2. The terms of the particular Transaction to which this Confirmation relates are as follows: 
  

			
	 General Terms:
	  	
		
	 Trade Date:
	  	June 24, 2011
		
	 Warrants:
	  	Equity call warrants, each giving the holder the right to purchase one Underlying Share at the Strike Price, subject to the Settlement Terms set forth below. For the purposes of
the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option.
		
	 Warrant Style:
	  	European

			
	 Seller:
	  	Company
		
	 Buyer:
	  	Bank
		
	 Shares:
	  	The shares of common stock of Company, par value USD 0.001 per Share (Exchange symbol “NUVA”)
		
	 Underlying Shares:
	  	The shares of Series A Participating Preferred Stock of Company, par value USD 0.001 per Share, which will have the rights and preferences, including the conversion, dividend,
liquidation and voting rights, as described in Annex A hereto, and which will be governed by the certificate of designations therefor (the “Certificate of Designations”). On the Premium Payment Date, the Certificate of
Designations shall supersede and replace such description in its entirety. Company hereby covenants and agrees with Bank that Company shall not issue any Underlying Shares except under, and as contemplated by, this Confirmation.
		
		  	For purposes of the Transaction, each reference to “Share” or “Shares” in Sections 1.20(a), 1.27, 2.1(c), 2.3(a)(ii), 9.4, 9.5, 9.7, 9.8, 9.9, 9.11, 9.12 and
10.5 of the Equity Definitions shall be read as a reference to “Underlying Share” or “Underlying Shares,” as the context requires, and each reference to “Share” or “Shares” in Sections 1.16, 11.2, 12.1(b),
12.1(f), 12.1(g), 12.1(h), 12.1(n), 12.2(e), 12.3(d), 12.4(b), 12.4(c), 12.6(a)(i), 12.6(a)(ii), 12.9(ii) and 13.4(c) of the Equity Definitions shall be read as a reference to “Share or Underlying Share” or “Shares or Underlying
Shares,” as the context requires.
		
	 Number of Warrants:
	  	31,151, subject to adjustment as provided herein.
		
	 Warrant Entitlement:
	  	One Underlying Share per Warrant
		
	 Strike Price:
	  	USD 988.51, which is equal to the product of USD 49.4253 and the Conversion Rate (as defined in the Certificate of Designations)
		
	 Premium:
	  	USD 3,123,750
		
	 Premium Payment Date:
	  	June 28, 2011
		
	 Exchange:
	  	The NASDAQ Global Select Market
		
	 Related Exchange(s):
	  	All Exchanges
		
	 Procedures for Exercise:
	  	
		
	 Expiration Time:
	  	The Valuation Time
		
	 Expiration Date(s):
	  	Each Scheduled Trading Day during the period from and including the First Expiration Date to and including the 80th Scheduled Trading Day following the First Expiration Date
shall be an “Expiration Date” for a number of Warrants equal to the Daily Number of Warrants on such date; provided that, notwithstanding anything to the contrary in the Equity Definitions, if any such date is a Disrupted Day, the
Calculation Agent shall make adjustments, if applicable, to the Daily Number

  
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		  	of Warrants or shall reduce such Daily Number of Warrants to zero for which such day shall be an Expiration Date and shall designate a Scheduled Trading Day or a number of
Scheduled Trading Days as the Expiration Date(s) for the remaining Daily Number of Warrants or a portion thereof for the originally scheduled Expiration Date; and provided further that if such Expiration Date has not occurred pursuant to this
clause as of the eighth Scheduled Trading Day following the last scheduled Expiration Date under this Transaction, the Calculation Agent shall have the right to declare such Scheduled Trading Day to be the final Expiration Date and the Calculation
Agent shall determine its good faith estimate of the fair market value for the Shares as of the Valuation Time on that eighth Scheduled Trading Day or on any subsequent Scheduled Trading Day, as the Calculation Agent shall determine using
commercially reasonable means.
		
	 First Expiration Date:
	  	September 29, 2017 (or if such day is not a Scheduled Trading Day, the next following Scheduled Trading Day), subject to Market Disruption Event below.
		
	 Daily Number of Warrants:
	  	For any Expiration Date, the Number of Warrants that have not expired or been exercised as of such day, divided by the remaining number of Expiration Dates (including such
day), rounded down to the nearest whole number, subject to adjustment pursuant to the provisos to “Expiration Date(s)”.
		
	 Automatic Exercise:
	  	Applicable; and means that a number of Warrants for each Expiration Date equal to the Daily Number of Warrants (as adjusted pursuant to the terms hereof) for such Expiration Date
will be deemed to be automatically exercised; provided that “In-the-Money” means that the Settlement Price for such Expiration Date exceeds the Strike Price for such Expiration Date; and provided further that all references
in Section 3.4(b) of the Equity Definitions to “Physical Settlement” shall be read as references to “Net Share Settlement”.
		
	 Market Disruption Event:
	  	Section 6.3(a)(ii) of the Equity Definitions is hereby amended (A) by replacing clause (ii) in its entirety with “(ii) an Exchange Disruption, or” and inserting
immediately following clause (iii) the phrase “; in each case that the Calculation Agent determines is material.” and (B) by replacing the words “or (iii) an Early Closure.” therein with “(iii) an Early Closure, or (iv) a
Regulatory Disruption.”
		
		  	Section 6.3(d) of the Equity Definitions is hereby amended by deleting the remainder of the provision following the term “Scheduled Closing Time” in the fourth line
thereof.
		
	 Regulatory Disruption:
	  	Any event that Bank, based upon advice of counsel, determines makes it appropriate with regard to any legal, regulatory or self-regulatory requirements or related policies and
procedures, for Bank to refrain from or decrease any market activity in connection with the Transaction. Bank shall notify Issuer as soon as reasonably practicable that a Regulatory Disruption has occurred and the Expiration Dates affected by
it.

  
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	 Valuation:
	  	
		
	 Valuation Time:
	  	Scheduled Closing Time; provided that if the principal trading session is extended, the Calculation Agent shall determine the Valuation Time in its reasonable
discretion.
		
	 Valuation Date:
	  	Each Exercise Date.
		
	 Settlement Terms:
	  	
		
	 Settlement Method Election:
	  	Applicable; provided that:
		
		  	 (i)       references to “Physical Settlement” in Section 7.1 of the Equity
Definitions shall be replaced with references to “Net Share Settlement”;

		
		  	 (ii)      Company may elect Cash Settlement only if, on or prior to the Settlement Method
Election Date, (x) Company delivers written notice to Bank stating that Company has elected that Cash Settlement apply and specifying the Expiration Dates to which such election applies and the percentage of Company’s settlement obligations,
which percentage shall be greater than 0% and less than or equal to 100%, that shall be settled in cash (the “Cash Percentage”), and (y) Bank delivers written consent to such election by Company by the second Scheduled Trading Day
immediately following the date on which such notice is delivered by Company, which consent will not be unreasonably withheld or delayed;

		
		  	 (iii)    Company may elect Cash Settlement only if Company represents and warrants to Bank in writing that
on the date of such election that (A) Company is not in possession of any material non-public information regarding Company or its securities, (B) Company is electing Cash Settlement in good faith and not as part of a plan or scheme to evade
compliance with the federal securities laws, and (C) the assets of Company at their fair valuation exceed the liabilities of Company (including contingent liabilities), the capital of Company is adequate to conduct the business of Company, and
Company has the ability to pay its debts and obligations as such debts mature and does not intend to, or does not believe that it will, incur debt beyond its ability to pay as such debts mature; and

		
		  	 (iii)    such Settlement Method Election shall apply to the Expiration Dates specified in such notice (or,
if none are specified, all Expiration Dates).

		
		  	At any time prior to making a Settlement Method Election, Company may, without the consent of Bank, amend this Confirmation by notice to Bank to eliminate Company’s right to
elect Cash Settlement.

  
 4 

			
		  	Notwithstanding the foregoing, in refusing to grant its consent with respect to Company’s Cash Settlement election, in addition to other reasons, Bank may refuse such grant
if Bank notifies Company that, in the reasonable judgment of Bank, the election of Cash Settlement or any purchases of Shares that Bank (or its affiliates) might make in connection therewith, based upon the advice of counsel, would raise material
risks under applicable securities laws.
		
	 Electing Party:
	  	Company
		
	 Settlement Method Election Date:
	  	The third Scheduled Trading Day immediately preceding the First Expiration Date.
		
	 Default Settlement Method:
	  	Net Share Settlement
		
	 Cash Percentage:
	  	0%; provided, however, that if Company (i) validly delivers notice of Cash Settlement hereunder and (ii) in such notice validly elects a Cash Percentage greater
than 0% and less than or equal to 100%, the Cash Percentage shall equal to the percentage specified as such in such notice.
		
	 Net Share Settlement:
	  	On the relevant Settlement Date, Company shall deliver to Bank the Share Delivery Quantity of Underlying Shares for such Settlement Date to the account specified hereto free of
payment through the Clearance System or in such other manner as the parties may agree.
		
	 Share Delivery Quantity:
	  	For any Settlement Date, a number of Underlying Shares, as calculated by the Calculation Agent, equal to the product of (i) one minus the Cash Percentage, expressed as a
fraction, and (ii) the Net Share Settlement Amount for such Settlement Date divided by the Settlement Price on the Valuation Date in respect of such Settlement Date, rounded down to the nearest whole number (for any Settlement Date, the
fraction of an Underlying Share eliminated by such rounding, the “Share Fraction” for such Settlement Date).
		
	 Fractional Share Amount:
	  	An amount of cash in USD equal to the product of (i) the Share Fraction for such Settlement Date and (ii) the Settlement Price on the Valuation Date for such Settlement
Date.
		
	 Net Share Settlement Amount:
	  	For any Settlement Date, an amount equal to the product of (i) the Number of Warrants exercised or deemed to be exercised on the relevant Exercise Date, (ii) the Strike
Price Differential for such Settlement Date and (iii) the Warrant Entitlement.
		
	 Cash Settlement:
	  	If Cash Settlement is applicable, then, on the relevant Settlement Date, Company shall (i) pay to Bank an amount of cash in USD equal to sum of (A) the product of (x) the Cash
Percentage and (y) the Net Share Settlement Amount for such Settlement Date and (B) the Fractional Share Amount, if any, for such Settlement Date and (ii) deliver to Bank a number of Underlying Shares equal to the Share Delivery Quantity for such
Settlement Date to the account specified hereto free of payment through the Clearance System or in such other manner as the parties may agree. The provisions opposite Net Share Settlement above shall apply to any Underlying Shares delivered pursuant
to clause (ii) of the immediately preceding sentence.

  
 5 

			
		
	 Settlement Price:
	  	For any Valuation Date, the product of the Conversion Rate (as defined in the Certificate of Designations) and the per Share volume-weighted average price as displayed under the
heading “Bloomberg VWAP” on Bloomberg page NUVA.UQ <equity> AQR (or any successor thereto) in respect of the period from the scheduled opening time of the Exchange to the Scheduled Closing Time on such Valuation Date (or if such
volume-weighted average price is unavailable or is, in the Calculation Agent’s reasonable discretion, erroneous, the market value of one Share on such Valuation Date, as determined by the Calculation Agent using a volume-weighted methodology).
Notwithstanding the foregoing, if (i) any Expiration Date is a Disrupted Day and (ii) the Calculation Agent determines that such Expiration Date shall be an Expiration Date for fewer than the Daily Number of Warrants, as described above, then the
Settlement Price for the relevant Valuation Date shall be the product of the Conversion Rate (as defined in the Certificate of Designations) and the volume-weighted average price per Share on such Valuation Date on the Exchange, as determined by the
Calculation Agent based on such sources as it deems appropriate using a volume-weighted methodology, for the portion of such Valuation Date for which the Calculation Agent determines there is no Market Disruption Event.
		
	 Settlement Date(s):
	  	As determined in reference to Section 9.4 of the Equity Definitions, subject to Section 9(k)(i) hereof.
		
	Other Applicable Provisions:	  	The provisions of Sections 9.9, 9.11, 9.12 and 10.5 of the Equity Definitions will be applicable, as if Physical Settlement were applicable, except that (i) Section 9.9 of the
Equity Definitions shall be amended by replacing the word “party” in the second line thereof with the word “Seller” and deleting the remainder of the provision and (ii) Section 10.5 shall be amended by replacing the word
“party” in the third line thereof with the word “Buyer” and deleting the remainder of the provision.
		
	Representation and Agreement:	  	Notwithstanding Section 9.11 of the Equity Definitions and subject to Sections 9(k) and 9(m) of this Confirmation, the parties acknowledge that any Underlying Shares delivered to
Bank may be, upon delivery, subject to restrictions and limitations arising from Company’s status as issuer of the Underlying Shares under applicable securities laws.
	 3. Additional Terms applicable to the Transaction:

	
	 Adjustments applicable to the Warrants:

		
	 Method of Adjustment:
	  	Calculation Agent Adjustment. For the avoidance of doubt, in making any adjustments under the Equity Definitions, the Calculation Agent may make adjustments, if any, to any one
or more of the Strike Price, the Number of Warrants, the Daily Number of Warrants and the Warrant Entitlement. Notwithstanding the foregoing, any dividends or distributions on the Shares or the Underlying Shares, whether or not extraordinary, shall
be governed by Section 9(f) of this Confirmation in lieu of Article 10 or Section 11.2(c) of the Equity Definitions.

  
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	 Extraordinary Events applicable to the Transaction:

		
	 New Shares:
	  	Section 12.1(i) of the Equity Definitions is hereby amended by deleting the text in clause (i) in its entirety and replacing it with the phrase “publicly quoted, traded or
listed on any of the New York Stock Exchange, The NASDAQ Global Select Market or The NASDAQ Global Market (or their respective successors)”.
		
	 Consequence of Merger Events:
	  	
		
	 Merger Event:
	  	Applicable: provided that if an event occurs that constitutes both a Merger Event under Section 12.1(b) of the Equity Definitions and Additional Termination Event under
Section 9(h)(ii)(A) of this Confirmation, Bank may elect, in its commercially reasonable judgment, whether the provisions of Section 12.1(b) of the Equity Definitions or Section 9(h)(ii)(A) will apply.
		
	 Share-for-Share:
	  	Modified Calculation Agent Adjustment
		
	 Share-for-Other:
	  	Cancellation and Payment (Calculation Agent Determination)
		
	 Share-for-Combined:
	  	Component Adjustment (Calculation Agent Determination)
		
	 Consequence of Tender Offers:
	  	
		
	 Tender Offer:
	  	Applicable; provided however that if an event occurs that constitutes both a Tender Offer under Section 12.1(d) of the Equity Definitions and Additional Termination Event
under Section 9(h)(ii)(C) of this Confirmation, Bank may elect, in its commercially reasonable judgment, whether the provisions of Section 12.3 of the Equity Definitions or Section 9(h)(ii)(C) will apply.
		
	 Share-for-Share:
	  	Modified Calculation Agent Adjustment
		
	 Share-for-Other:
	  	Modified Calculation Agent Adjustment
		
	 Share-for-Combined:
	  	Modified Calculation Agent Adjustment
		
	 Modified Calculation
	  	
	 Agent Adjustment:
	  	If, in respect of any Merger Event to which Modified Calculation Agent Adjustment applies, the adjustments to be made in accordance with Section 12.2(e)(i) of the Equity
Definitions would result in Issuer being different from the issuer of the Shares or the Underlying Shares, then with respect to such Merger Event, as a condition precedent to the adjustments contemplated in Section 12.2(e)(i) of the Equity
Definitions, Issuer and the issuer of the Shares or the Underlying Shares shall, prior to the Merger Date, have entered into such documentation containing representations, warranties and agreements relating to securities law and other issues as
requested by Bank that Bank has determined, in its commercially reasonable discretion, to be

  
 7 

			
		  	reasonably necessary or appropriate to allow Bank to continue as a party to the Transaction, as adjusted under Section 12.2(e)(i) of the Equity Definitions, and to preserve its
hedging or hedge unwind activities in connection with the Transaction in a manner compliant with applicable legal, regulatory or self-regulatory requirements, or with related policies and procedures applicable to Bank, and if such conditions are not
met or if the Calculation Agent determines that no adjustment that it could make under Section 12.2(e)(i) of the Equity Definitions will produce a commercially reasonable result, then the consequences set forth in Section 12.2(e)(ii) of the Equity
Definitions shall apply.
		
	 Reference Markets:
	  	For the avoidance of doubt, and without limiting the generality of the foregoing provisions, any adjustment effected by the Calculation Agent pursuant to Section 12.2(e) and/or
Section 12.3(d) of the Equity Definitions may be determined by reference to the adjustment(s) made in respect of Merger Events or Tender Offers, as the case may be, in the convertible bond market.
		
	 Nationalization, Insolvency or Delisting:
	  	Cancellation and Payment (Calculation Agent Determination); provided that, in addition to the provisions of Section 12.6(a)(iii) of the Equity Definitions, it will also
constitute a Delisting if the Exchange is located in the United States and the Shares are not immediately re-listed, re-traded or re-quoted on any of the New York Stock Exchange, The NASDAQ Global Select Market or The NASDAQ Global Market (or their
respective successors); if the Shares are immediately re-listed, re-traded or re-quoted on any of the New York Stock Exchange, The NASDAQ Global Select Market or The NASDAQ Global Market (or their respective successors), such exchange or quotation
system shall thereafter be deemed to be the Exchange.
		
	 Additional Disruption Events:
	  	
		
	 Change in Law:
	  	Applicable; provided that Section 12.9(a)(ii) of the Equity Definitions is hereby amended by (w) adding the words “(including, for the avoidance of doubt and without
limitation, adoption or promulgation of new regulations authorized or mandated by existing statute)” after the word “regulation” in the second line thereof, (x) adding the words “or any Hedge Positions” after the word
“Shares” in the clause (X) thereof and (y) adding the words “, or holding, acquiring or disposing of Shares or any Hedge Positions relating,” after the word “obligations” in clause (Y) thereof.
		
		  	The parties agree that, for purposes of Section 12.9(a)(ii) of the Equity Definitions, “any applicable law or regulation” shall include the Dodd-Frank Wall Street
Reform and Consumer Protection Act of 2010, any rules and regulations promulgated thereunder and any similar law or regulation, and the consequences specified in Section 12.9(b)(i) of the Equity Definitions shall apply to any Change in Law arising
from any such act, rule or regulation.
		
	 Failure to Deliver:
	  	Not Applicable
		
	 Insolvency Filing:
	  	Applicable

  
 8 

			
	 Hedging Disruption:
	  	Applicable; provided that:
		
		  	 (i)       Section 12.9(a)(v) of the Equity Definitions is hereby amended by inserting the
following two phrases at the end of such Section:

		
		  	 “For the avoidance of doubt, the term “equity price risk” shall be deemed to include stock price and volatility risk. And, for the
further avoidance of doubt, any such transactions or assets referred to in phrases (A) or (B) above must be available on commercially reasonable pricing terms.”; and

		
		  	 (ii)      Section 12.9(b)(iii) of the Equity Definitions is hereby amended by inserting in the
third line thereof, after the words “to terminate the Transaction”, the words “or a portion of the Transaction affected by such Hedging Disruption”.

		
	 Increased Cost of Hedging:
	  	Applicable
		
	 Loss of Stock Borrow:
	  	Applicable
		
	 Maximum Stock Loan Rate:
	  	 100 basis points.

		
	 Increased Cost of Stock Borrow:
	  	Applicable
		
	 Initial Stock Loan Rate:
	  	 25 basis points.

		
	 Hedging Party:
	  	Bank for all applicable Additional Disruption Events
		
	 Determining Party:
	  	Bank for all applicable Extraordinary Events; provided that Bank shall make all determinations required pursuant to this Transaction, in a commercially reasonable
manner.
		
	 Non-Reliance:
	  	Applicable
		
	 Agreements and Acknowledgments
	  	
	 Regarding Hedging Activities:
	  	Applicable
		
	 Additional Acknowledgments:
	  	Applicable
		
	 Illegality:
	  	The parties agree that, for the avoidance of doubt, for purposes of Section 5(b)(i) of the Agreement, “any applicable law” shall include the Dodd-Frank Wall Street
Reform and Consumer Protection Act of 2010, any rules and regulations promulgated thereunder and any similar law or regulation, without regard to Section 739 of the Dodd-Frank Wall Street Reform and Consumer Protection Act of 2010 or any similar
legal certainty provision in any legislation enacted, or rule or regulation promulgated, on or after the Trade Date, and the consequences specified in the Agreement, including without limitation, the consequences specified in Section 6 of the
Agreement, shall apply to any Illegality arising from any such act, rule or regulation.
		
	 4. Calculation Agent:
	  	Bank; provided that (i) if an Event of Default as a result of Section 5(a)(vii) of the Agreement has occurred and is continuing with respect to Bank, the Calculation Agent
shall be a leading recognized dealer in equity derivatives designated in good faith by Company for so long as such Event of Default is continuing and (ii) Calculation Agent shall make all calculations, adjustments and determinations required
pursuant to this Transaction, in a commercially reasonable manner.

  
 9 

 5. Account Details: 
  

	 	(a)	Account for payments to Company: 

To be provided by Company. 
 Account for delivery of Underlying Shares from Company if settlements occur through the Clearance System: 
 To be provided by Bank. 
  

	 	(b)	Account for payments to Bank: 

Chase Manhattan Bank New York 
 For A/C Goldman, Sachs & Co. 
 A/C #930-1-011483 

ABA: 021-000021 

Account for delivery of Underlying Shares to Bank if settlements occur through the Clearance System: 

To be provided by Bank. 
 6.
Offices: 
 The Office of Company for the Transaction is: Inapplicable, Company is not a Multibranch Party. 

The Office of Bank for the Transaction is: 200 West Street, New York, NY 10282-2198 
 7. Notices: For purposes of this Confirmation: 
  

	 	(a)	Address for notices or communications to Company: 

 NuVasive, Inc. 
 7475 Lusk Blvd 

San Diego, CA 92121 
 Attention: Chief Financial Officer 

	 	Telephone No.:	858-909-1800 

	 	Facsimile No.:	858-909-2000 

  

	 	(b)	Address for notices or communications to Bank: 

 Bank notice information to follow: 
 Bank notice information to follow: 

 

	 	To:	Goldman, Sachs & Co. 

	 	 	200 West Street 

	 	 	New York, NY 10282-2198 

	 	Attn:	Serge Marquié, 

	 	 	Equity Capital Markets 

	 	Telephone:	212-902-9779 

	 	Facsimile:	917-977-4253 

	 	Email:	marqse@am.ibd.gs.com 

  
 10 

 With a copy to: 

 

	 	Attention:	Kevin Castellano, Equity Capital Markets 

	 	Equity	Capital Markets 

	 	Telephone:	+1-212-902-3511 

	 	Facsimile:	+1-212-256-4336 

	 	Email:	kevin.castellano@gs.com 

And email notification to the following address: 
 Eq-derivs-notifications@am.ibd.gs.com 
 8. Representations, Warranties and Agreements of
Company and Bank 
  

	 	(a)	The representations and warranties of Company set forth in Section 1(a) of the Underwriting Agreement (the “Underwriting Agreement”) dated as of
June 22, 2011 among Company, Merrill Lynch, Pierce, Fenner & Smith Incorporated and Goldman, Sachs & Co., as Representatives of the Underwriters (the “Underwriters”), are true and correct and are hereby deemed
to be repeated to Bank as if set forth herein. Company hereby further represents and warrants to Bank that on the Trade Date and the Premium Payment Date: 

  

	 	(i)	Company has all necessary corporate power and authority to execute, deliver and perform its obligations in respect of this Transaction; such execution, delivery and
performance have been duly authorized by all necessary corporate action on Company’s part; and this Confirmation has been duly and validly executed and delivered by Company and constitutes its valid and binding obligation, enforceable against
Company in accordance with its terms, subject to applicable bankruptcy, insolvency, fraudulent conveyance, reorganization, moratorium and similar laws affecting creditors’ rights and remedies generally, and subject, as to enforceability, to
general principles of equity, including principles of commercial reasonableness, good faith and fair dealing (regardless of whether enforcement is sought in a proceeding at law or in equity) and except that rights to indemnification and contribution
hereunder may be limited by federal or state securities laws or public policy relating thereto. 

  

	 	(ii)	Neither the execution and delivery of this Confirmation nor the incurrence or performance of obligations of Company hereunder will conflict with or result in a breach
of the certificate of incorporation or by-laws (or any equivalent documents) of Company, or any applicable law or regulation, or any order, writ, injunction or decree of any court or governmental authority or agency applicable to the Company, or any
agreement or instrument to which Company or any of its subsidiaries is a party or by which Company or any of its subsidiaries is bound or to which Company or any of its subsidiaries is subject, or constitute a default under, or result in the
creation of any lien under, any such agreement or instrument. 

  

	 	(iii)	No consent, approval, authorization, or order of, or filing with, any governmental agency or body or any court is required by Company in connection with the execution,
delivery or performance by Company of this Confirmation, except such as have been obtained or made and such as may be required under the Securities Act of 1933, as amended (the “Securities Act”) or state securities laws.

  

	 	(iv)	 In the event that the stockholder approvals described in Section 9(x) are received, the Underlying Shares initially issuable upon exercise of the
Warrants by the net share settlement method (the “Warrant Shares”), and the Shares initially issuable upon conversion of the Warrant Shares (the “Conversion Shares”), will have been reserved for issuance by all
required corporate action of Company. The Warrant Shares and the 

  
 11 

	 	 
Conversion Shares have been duly authorized and, when (i) in the case of the Warrant Shares, the Warrant Shares are delivered against payment therefor (which may include Net Share Settlement
in lieu of cash) and otherwise as contemplated by the terms of the Warrant following the exercise of the Warrant in accordance with the terms and conditions of the Warrant and (ii) in the case of the Conversion Shares, the Conversion Shares are
delivered upon conversion of the Warrant Shares in accordance with the certificate of designations for the Conversion Shares, will be validly issued, fully-paid and non-assessable, and the issuance of the Warrant Shares and the Conversion Shares
will not be subject to any preemptive or similar rights. 

  

	 	(v)	Company is not and will not be required to register as an “investment company” as such term is defined in the Investment Company Act of 1940, as amended.

  

	 	(vi)	Company is an “eligible contract participant” (as such term is defined in Section 1a(17) of the Commodity Exchange Act, as amended).

  

	 	(vii)	During the period starting on the first Expiration Date and ending on the last Expiration Date (the “Settlement Period”), neither Company nor any
“affiliate” or “affiliated purchaser” (each as defined in Rule 10b-18 (“Rule 10b-18”) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”)) shall directly or indirectly
(including, without limitation, by means of any cash-settled or other derivative instrument) purchase, offer to purchase, place any bid or limit order that would effect a purchase of, or commence any tender offer relating to, any Shares (or an
equivalent interest, including a unit of beneficial interest in a trust or limited partnership or a depository share) or any security convertible into or exchangeable or exercisable for Shares, except through Bank. 

 

	 	(viii)	Without limiting the generality of Section 13.1 of the Equity Definitions, Company acknowledges that Bank is not making any representations or warranties with
respect to the treatment of the Transaction under FASB Statements 128, 133 (as amended), 149 or 150, EITF Issue No. 00-19, 01-6 or 03-6 (or any successor issue statements) or under any accounting standards including FASB’s
Liabilities & Equity Project. 

  

	 	(ix)	Prior to the Trade Date, Company shall deliver to Bank a resolution of Company’s board of directors authorizing the Transaction and such other certificate or
certificates as Bank shall reasonably request. 

  

	 	(x)	Company is not “insolvent” (as such term is defined under Section 101(32) of the U.S. Bankruptcy Code (Title 11 of the United States Code) (the
“Bankruptcy Code”)). 

  

	 	(xi)	Company understands no obligations of Bank to it hereunder will be entitled to the benefit of deposit insurance and that such obligations will not be guaranteed by any
affiliate of Bank or any governmental agency. 

  

	 	(xii)	 Company agrees that it (A) will not during the Settlement Period make, or permit to be made, any public announcement (as defined in Rule 165(f)
under the Securities Act) of any Merger Transaction or potential Merger Transaction unless such public announcement is made prior to the opening or after the close of the regular trading session on the Exchange for the Shares; (B) shall
promptly (but in any event prior to the next opening of the regular trading session on the Exchange) notify Bank following any such announcement that such announcement has been made; and (C) shall promptly (but in any event prior to the next
opening of the regular trading session on the Exchange) provide Bank with written notice specifying (i) Company’s average daily Rule 10b-18 Purchases (as defined in Rule 10b-18) during the three full calendar months immediately preceding
the announcement date that were not effected through Bank or its affiliates and (ii) the number of Shares purchased pursuant to the proviso in Rule 10b-18(b)(4) under the Exchange Act for the three full calendar months preceding the
announcement date. 

  
 12 

	 	 
Such written notice shall be deemed to be a certification by Company to Bank that such information is true and correct. In addition, Company shall promptly notify Bank of the earlier to occur of
the completion of such transaction and the completion of the vote by target shareholders. “Merger Transaction” means any merger, acquisition or similar transaction involving a recapitalization as contemplated by Rule 10b-18(a)(13)(iv)
under the Exchange Act. 

  

	 	(b)	Each of Bank and Company acknowledges that the offer and sale of the Transaction to it is intended to be exempt from registration under the Securities Act, by virtue of
Section 4(2) thereof. Accordingly, Bank represents and warrants to Company that (i) it has the financial ability to bear the economic risk of its investment in the Transaction and is able to bear a total loss of its investment and its
investments in and liabilities in respect of the Transaction, which it understands are not readily marketable, are not disproportionate to its net worth, and it is able to bear any loss in connection with the Transaction, including the loss of its
entire investment in the Transaction, (ii) it is an “accredited investor” as that term is defined in Regulation D as promulgated under the Securities Act, (iii) it is entering into the Transaction for its own account without a
view to the distribution or resale thereof, (iv) the assignment, transfer or other disposition of the Transaction has not been and will not be registered under the Securities Act and is restricted under this Confirmation, the Securities Act and
state securities laws, (v) its financial condition is such that it has no need for liquidity with respect to its investment in the Transaction and no need to dispose of any portion thereof to satisfy any existing or contemplated undertaking or
indebtedness and is capable of assessing the merits of and understanding (on its own behalf or through independent professional advice), and understands and accepts, the terms, conditions and risks of the Transaction. 

 

	 	(c)	Each party acknowledges and agrees to be bound by the Conduct Rules of the National Association of Securities Dealers, Inc. applicable to transactions in options, and
further agrees not to violate the position and exercise limits set forth therein. 

  

	 	(d)	Company represents and warrants that it has received, read and understands the OTC Options Risk Disclosure Statement and a copy of the most recent disclosure pamphlet
prepared by The Options Clearing Corporation entitled “Characteristics and Risks of Standardized Options”. 

 9. Other
Provisions: 
  

	 	(a)	Opinions. Company shall deliver an opinion of counsel, dated as of the Trade Date, to Bank with respect to the matters set forth in Sections 8(a)(i)
through (iv) of this Confirmation; provided that, with respect to “any agreement or instrument” referred to in Section 8(a)(ii), such opinion shall only refer to agreements and instruments filed as exhibits to
Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2010, as updated by any exhibits to Current Reports on Form 8-K filed on January 6, 2011, January 11, 2011, January 19,
2011, February 3, 2011, February 23, 2011, March 9, 2011, May 5, 2011 and May 31, 2011. 

  

	 	(b)	 Repurchase Notices. Company shall, on any day on which Company effects any repurchase of Shares, promptly give Bank a written notice of
such repurchase (a “Repurchase Notice”) on such day if following such repurchase, the quotient of (x) the sum of (a) the product of the Number of Warrants, the Warrant Entitlement and the Conversion Rate (as defined in the
Certificate of Designations), (b) the product of the “Number of Warrants” and the “Warrant Entitlement” (each as defined in the letter agreement dated June 22, 2011 between Bank and Company regarding Base Warrants (the
“Base Warrant Confirmation”)) and the Conversion Rate, and (c) the product of the “Number of Warrants” and the “Warrant Entitlement” (each as defined in the letter agreement between Company and Bank dated as
of March 3, 2008, as amended by the letter agreement between Company and Bank dated as of March 11, 2008), divided by (y) the number of Company’s outstanding Shares (such quotient expressed as a percentage, the
“Warrant Equity Percentage”) would be (i) greater than 7.5% or (ii) 0.5% greater than the Warrant Equity Percentage included in the immediately preceding Repurchase Notice. Company agrees to

  
 13 

	 	 
indemnify and hold harmless Bank and its affiliates and their respective officers, directors, employees, affiliates, advisors, agents and controlling persons (each, an “Indemnified
Person”) from and against any and all losses (including losses relating to Bank’s hedging activities as a consequence of becoming, or of the risk of becoming, a Section 16 “insider”, including without limitation, any
forbearance from hedging activities or cessation of hedging activities and any losses in connection therewith with respect to this Transaction), claims, damages, judgments, liabilities and expenses (including reasonable attorney’s fees), joint
or several, which an Indemnified Person actually may become subject to, as a result of Company’s failure to provide Bank with a Repurchase Notice on the day and in the manner specified in this paragraph, and to reimburse, within 30 days, upon
written request, each of such Indemnified Persons for any reasonable legal or other expenses incurred in connection with investigating, preparing for, providing testimony or other evidence in connection with or defending any of the foregoing. If any
suit, action, proceeding (including any governmental or regulatory investigation), claim or demand shall be brought or asserted against the Indemnified Person, such Indemnified Person shall promptly notify Company in writing, and Company, upon
request of the Indemnified Person, shall retain counsel reasonably satisfactory to the Indemnified Person to represent the Indemnified Person and any others Company may designate in such proceeding and shall pay the fees and expenses of such counsel
related to such proceeding. Company shall not be liable for any settlement of any proceeding effected without its written consent, but if settled with such consent or if there be a final judgment for the plaintiff, Company agrees to indemnify any
Indemnified Person from and against any loss or liability by reason of such settlement or judgment. Company shall not, without the prior written consent of the Indemnified Person, effect any settlement of any pending or threatened proceeding in
respect of which any Indemnified Person is or could have been a party and indemnity could have been sought hereunder by such Indemnified Person, unless such settlement includes an unconditional release of such Indemnified Person from all liability
on claims that are the subject matter of such proceeding on terms reasonably satisfactory to such Indemnified Person. If the indemnification provided for in this paragraph is unavailable to an Indemnified Person or insufficient in respect of any
losses, claims, damages or liabilities referred to therein, then Company under such paragraph, in lieu of indemnifying such Indemnified Person thereunder, shall contribute to the amount paid or payable by such Indemnified Person as a result of such
losses, claims, damages or liabilities. The remedies provided for in this paragraph are not exclusive and shall not limit any rights or remedies which may otherwise be available to any Indemnified Person at law or in equity. The indemnity and
contribution agreements contained in this paragraph shall remain operative and in full force and effect regardless of the termination of the Transaction. 

 

	 	(c)	Regulation M. Company shall not, during the period starting on the first Expiration Date and ending on second Scheduled Trading Day immediately following
the last Expiration Date, engaged in a distribution, as such term is used in Regulation M under the Exchange Act, of any securities of Company, other than a distribution meeting the requirements of the exception set forth in Rules 101(b)(10) and
102(b)(7) of Regulation M. 

  

	 	(d)	No Manipulation. Company is not entering into this Transaction (i) on the basis of, and it is not aware of, any material non-public information with
respect to itself, the Underlying Shares or the Shares (ii) in anticipation of, in connection with, or to facilitate, a distribution of its securities, a self tender offer or a third-party tender offer or (iii) to create actual or apparent
trading activity in the Shares (or any security convertible into or exchangeable for the Shares) or to raise or depress or otherwise manipulate the price of the Shares (or any security convertible into or exchangeable for the Shares) or otherwise in
violation of the Exchange Act. 

  

	 	(e)	 Transfer or Assignment. Company may not transfer any of its rights or obligations under this Transaction without the prior written
consent of Bank. Bank may, without Company’s consent, transfer or assign all or any part of its rights or obligations under this Transaction to any third party (the “Transferee”). If after Bank’s commercially reasonable
efforts, Bank is unable to effect such a transfer or assignment on pricing terms reasonably acceptable to Bank and within a time period reasonably acceptable to Bank, or the Transfer Conditions set forth below are not satisfied following a proposed
transfer or assignment, of a sufficient number of Warrants to reduce (i) Bank 

  
 14 

	 	 
Group’s “beneficial ownership” (within the meaning of Section 13 of the Exchange Act and rules promulgated thereunder) to 8.0% of Company’s outstanding Shares or less or
(ii) the Warrant Equity Percentage to 14.5% or less, Bank may designate any Exchange Business Day as an Early Termination Date with respect to a portion (the “Terminated Portion”) of this Transaction, such that (i) Bank
Group’s “beneficial ownership” following such partial termination will be equal to or less than 8.0% or (ii) the Warrant Equity Percentage following such partial termination will be equal to or less than 14.5%. In the event that
Bank so designates an Early Termination Date with respect to a portion of this Transaction, a payment shall be made pursuant to Section 6 of the Agreement as if (i) an Early Termination Date had been designated in respect of a Transaction
having terms identical to this Transaction and a Number of Warrants equal to the Terminated Portion, (ii) Company shall be the sole Affected Party with respect to such partial termination and (iii) such Transaction shall be the only
Terminated Transaction (and, for the avoidance of doubt, the provisions of paragraph 9(j) shall apply to any amount that is payable by Company to Bank pursuant to this sentence). Notwithstanding any other provision in this Confirmation to the
contrary (including the Transfer Conditions below) requiring or allowing Bank to purchase, sell, receive or deliver any Shares or other securities to or from Company, Bank may designate any of its affiliates to purchase, sell, receive or deliver
such Shares or other securities and otherwise to perform Bank’s obligations in respect of this Transaction and any such designee may assume such obligations. Bank shall be discharged of its obligations to Company to the extent of any such
performance. “Bank Group” means Bank or any affiliate of Bank subject to aggregation with Bank under such Section 13 of the Exchange Act and rules promulgated thereunder and all persons who may form a “group” (within
the meaning of Rule 13d-5(b)(1) under the Exchange Act) with Bank. 

 Notwithstanding the foregoing, but
subject to the right to designate an affiliate as set forth above, Bank may not transfer or assign under this Section 9(e) unless the following conditions are satisfied (the “Transfer Conditions”): 

(1) the Transferee agrees in writing with Bank to be bound by the terms of this Confirmation with respect to the transferred obligations;

 (2) as of the date of such transfer, and giving effect thereto, Company will not be required to withhold or deduct on account
of Tax from any payments under the Agreement or will be required to gross up for such Tax under Section 2(d)(i)(4) of the Agreement; 
 (3) as of the date of such transfer, and giving effect thereto, Bank or the Transferee will not be required to gross up for such Tax under Section 2(d)(i)(4) of the Agreement; 

(4) no Event of Default where Bank or the Transferee is the Defaulting Party or Termination Event where Bank or the Transferee is the
sole Affected Party will occur as a result of such transfer; and 
 (5) as of the date of such transfer, and giving effect
thereto, the transfer will not result in a Change in Law. 
  

	 	(f)	Dividends. If at any time during the period from but excluding the Trade Date, to and including the Expiration Date, an ex-dividend date for a dividend or
distribution occurs with respect to the Shares or the Underlying Shares, then the Calculation Agent will adjust any of the Strike Price, Warrant Entitlement, Number of Warrants and/or Daily Number of Warrants to preserve the fair value of the
Warrants to Bank after taking into account such dividend or distribution or lack thereof. 

  

	 	(g)	[Reserved.] 

  
 15 

	 	(h)	Additional Provisions. 

  

	 	(i)	Amendments to the Equity Definitions: 

 (A) Section 11.2(a) of the Equity Definitions is hereby amended by deleting the words “a diluting or concentrative” and replacing them with the words “an”; and adding the phrase
“, Warrants or Underlying Shares” at the end of the sentence. 
 (B) Section 11.2(c) of the Equity Definitions is
hereby amended by (x) replacing the words “a diluting or concentrative” with “an”, (y) adding the phrase “, Warrants or Underlying Shares” after the words “the relevant Shares” in the same sentence
and (z) deleting the phrase “(provided that no adjustments will be made to account solely for changes in volatility, expected dividends, stock loan rate or liquidity relative to the relevant Shares)” and replacing it with the
phrase “(and, for the avoidance of doubt, adjustments may be made to account solely for changes in volatility, expected dividends, stock loan rate or liquidity relative to the relevant Shares).” 

(C) Section 11.2(e)(vii) of the Equity Definitions is hereby amended by deleting the words “a diluting or concentrative”
and replacing them with the word “an”; and adding the phrase “, Warrants or Underlying Shares” at the end of the sentence. 
 (D) Section 12.6(a)(ii) of the Equity Definitions is hereby amended by (1) deleting from the fourth line thereof the word “or” after the word “official” and inserting a comma
therefor, and (2) deleting the semi-colon at the end of subsection (B) thereof and inserting the following words therefor “or (C) at Bank’s option, the occurrence of any of the events specified in Section 5(a)(vii)
(1) through (9) of the ISDA Master Agreement with respect to that Issuer.” 
 (E) Section 12.9(b)(iv) of the
Equity Definitions is hereby amended by: 
 (x) deleting (1) subsection (A) in its entirety, (2) the phrase
“or (B)” following subsection (A) and (3) the phrase “in each case” in subsection (B); and 
 (y)
deleting the phrase “neither the Non-Hedging Party nor the Lending Party lends Shares in the amount of the Hedging Shares or” in the penultimate sentence. 
 (F) Section 12.9(b)(v) of the Equity Definitions is hereby amended by: 
 (x)
adding the word “or” immediately before subsection “(B)” and deleting the comma at the end of subsection (A); and 
 (y)(1) deleting subsection (C) in its entirety, (2) deleting the word “or” immediately preceding subsection (C) and (3) deleting the penultimate sentence in its entirety and
replacing it with the sentence “The Hedging Party will, in a commercially reasonable manner, determine the Cancellation Amount payable by one party to the other.” 
 (ii) Notwithstanding anything to the contrary in this Confirmation, upon the occurrence of one of the following events, with respect to this Transaction, (1) Bank shall have the right to designate
such event an Additional Termination Event and designate an Early Termination Date pursuant to Section 6(b) of the Agreement, and (2) Company shall be deemed the sole Affected Party and the Transaction shall be deemed the sole Affected
Transaction: 
 (A) Any person files a Schedule TO, or any schedule, form or report under the Exchange Act, disclosing that such
person has acquired beneficial ownership, directly or indirectly, through a purchase, merger or other acquisition transaction or series of transactions, of shares of Company’s capital stock entitling such person to exercise 50% or more of the
total voting power of all shares of Company’s capital stock entitled to vote generally in elections of directors, other than an acquisition by Company or any of its 

  
 16 

 
subsidiaries or any of Company’s employee benefit plans. For purposes of this provision, whether a person is a “beneficial owner” will be determined in accordance with Rule
13d-3 under the Exchange Act, and “person” includes any syndicate or group that would be deemed to be a “person” under Section 13(d)(3) of the Exchange Act. 

(B) Company (i) merges or consolidates with or into any other person, other than one of its subsidiaries, another person merges with
or into Company, or Company conveys, sells, transfers or leases all or substantially all of its assets to another person or (ii) engages in any recapitalization, reclassification or other transaction in which all or substantially all the Shares
are exchanged for or converted into cash, securities or other property, in each case, other than any merger or consolidation: 

(x) that does not result in a reclassification, conversion, exchange or cancellation of outstanding Shares; 

(y) pursuant to which the consideration received by holders of Shares immediately prior to the transaction entitles such holders to
exercise, directly or indirectly, 50% or more of the voting power of all shares of capital stock entitled to vote generally in the election of directors of the continuing or surviving corporation immediately after such transaction; or 

(z) which is effected solely to change Company’s jurisdiction of incorporation and results in a reclassification, conversion or
exchange of outstanding Shares solely into shares of common stock of the surviving entity. 
 (C) Company is liquidated or
dissolved or holders of Shares approve any plan or proposal for Company’s liquidation or dissolution. 
 (D) There is a
default by Company or any significant subsidiary in the payment at final maturity or upon acceleration of indebtedness for money borrowed by Company or any significant subsidiary of Company in excess of $30 million in the aggregate, whether such
debt now exists or shall hereafter be created, and such indebtedness is not discharged, or such acceleration is not cured or rescinded, within a period of 30 days after the occurrence of such debt becoming or being declared due and payable or the
failure to pay, as the case may be. For purposes of this provision, “significant subsidiary” means, in respect of any person, a Subsidiary of such person that would constitute a “significant subsidiary”, as such term is
defined in Rule 1-02 of Regulation S-X promulgated by the SEC as in effect on the date hereof. 
 (E) Shares, or shares of any
other capital stock or American Depositary Receipts in respect of shares of capital stock into which Company’s notes are convertible, are not listed for trading on any of The New York Stock Exchange, The NASDAQ Global Market or The NASDAQ
Global Select Market (or any of their respective successors). 
 (F) Bank, despite using commercially reasonable efforts, is
unable or reasonably determines that it is impractical or illegal, to hedge its obligations pursuant to this Transaction in the public market without registration under the Securities Act or as a result of any legal, regulatory or self-regulatory
requirements or related policies and procedures (whether or not such requirements, policies or procedures are imposed by law or have been voluntarily adopted by Bank). 
 Notwithstanding the forgoing, any merger or consolidation under clause (A) or any event specified under clause (B) above will not constitute an Additional Termination Event if at least at least
90% of the consideration paid for the Shares (excluding cash payments for fractional Shares and cash payments made pursuant to dissenters’ appraisal rights) in connection with such event consists of shares of common stock traded on any of The
New York Stock Exchange, The NASDAQ Global Market or The NASDAQ Global Select Market (or any of their respective successors) (or will be so traded or quoted immediately following the completion of the merger or consolidation or other transaction).

  
 17 

	 	(i)	No Collateral or Setoff. Notwithstanding any provision of the Agreement, the Confirmation or the Equity Definitions or any other agreement between the
parties to the contrary, the obligations of Company hereunder are not secured by any collateral. Obligations under this Transaction shall not be set off by Company against any other obligations of the parties, whether arising under the Agreement,
this Confirmation or the Equity Definitions, under any other agreement between the parties hereto, by operation of law or otherwise. Any provision in the Agreement with respect to the satisfaction of Company’s payment obligations to the extent
of Bank’s payment obligations to Company in the same currency and in the same Transaction (including, without limitation Section 2(c) thereof) shall not apply to Company and, for the avoidance of doubt, Company shall fully satisfy such
payment obligations notwithstanding any payment obligation to Company by Bank in the same currency and in the same Transaction. In calculating any amounts under Section 6(e) of the Agreement or Section 12 of the Equity Definitions,
notwithstanding anything to the contrary in the Agreement or the Equity Definitions, (1) separate amounts shall be calculated as set forth in Section 6(e) of the Agreement or Section 12 of the Equity Definitions, as applicable, with
respect to this Transaction, and (2) such separate amounts shall be payable pursuant to Section 6(d)(ii) of the Agreement or Section 12 of the Equity Definitions. For the avoidance of doubt and notwithstanding anything to the contrary
provided in this Section 9(i), in the event of bankruptcy or liquidation of Company neither party shall have the right to set off any obligation that it may have to the other party under this Transaction against any obligation such other party
may have to it, whether arising under the Agreement, this Confirmation, the Equity Definitions or any other agreement between the parties hereto, by operation of law or otherwise. 

 

	 	(j)	Alternative Calculations and Payment on Early Termination and on Certain Extraordinary Events. If, in respect of this Transaction, an amount is payable by
Company to Bank, (i) pursuant to Section 12.2, 12.3, 12.6, 12.7 or Section 12.9 of the Equity Definitions (except in the event of an Insolvency, Nationalization, Tender Offer or Merger Event in which the consideration or proceeds to
be paid to holders of Shares consists solely of cash) or (ii) pursuant to Sections 6(d) and 6(e) of the Agreement (except in the event of an Event of Default in which Company is the Defaulting Party or a Termination Event in which Company is
the Affected Party, other than an Event of Default of the type described in (x) Section 5(a)(iii), (v), (vi), (vii) or (viii) of the Agreement or (y) a Termination Event of the type described in Section 5(b) of the
Agreement, in the case of both (x) and (y), resulting from an event or events outside Company’s control) (a “Payment Obligation”), Company shall have the right, in its sole discretion, to satisfy any such Payment
Obligation by the Share Termination Alternative (as defined below) by giving irrevocable telephonic notice to Bank, confirmed in writing within one Scheduled Trading Day, no later than 12:00 p.m. New York local time on the Merger Date, Tender Offer
Date, Announcement Date (in the case of a Nationalization, Insolvency or Delisting), Early Termination Date or, in the case of an Additional Disruption Event, date of cancellation, as applicable; provided that if Company does not validly
elect to satisfy its Payment Obligation by the Share Termination Alternative and Company has received Shareholder Approval (as defined in the Certificate of Designations) and shall have notified Bank of such receipt, Bank shall have the right to
require Company to satisfy its Payment Obligation by the Share Termination Alternative. Notwithstanding the foregoing, Company’s or Bank’s right to elect satisfaction of a Payment Obligation in the Share Termination Alternative as set
forth in this clause shall only apply to Transactions under this Confirmation. 

  

			
	Share Termination Alternative:	  	If applicable, Company shall deliver to Bank the Share Termination Delivery Property on the date (the “Share Termination Payment Date”) on which the Payment
Obligation would otherwise be due pursuant to Section 12.2, 12.3, 12.6, 12.7 or Section 12.9 of the Equity Definitions and Sections 6(d) and 6(e) of the Agreement, as applicable, subject to paragraph (k)(i) below, in satisfaction, subject to
paragraph (k)(ii) below, of the Payment Obligation in the manner reasonably requested by Bank free of payment.

  
 18 

			
		
	Share Termination Delivery Property:	  	A number of Share Termination Delivery Units, as calculated by the Calculation Agent, equal to the Payment Obligation divided by the Share Termination Unit Price. The
Calculation Agent shall adjust the amount of Share Termination Delivery Property by replacing any fractional portion of a security therein with an amount of cash equal to the value of such fractional security based on the values used to calculate
the Share Termination Unit Price.
		
	Share Termination Unit Price:	  	The value to Bank of property contained in one Share Termination Delivery Unit on the date such Share Termination Delivery Units are to be delivered as Share Termination Delivery
Property, as determined by the Calculation Agent in its discretion by commercially reasonable means. The Calculation Agent shall notify Company of such Share Termination Unit Price at the time of notification of the Payment Obligation. In the case
of a Private Placement of Share Termination Delivery Units that are Restricted Shares (as defined below), as set forth in paragraph (k)(i) below, the Share Termination Unit Price shall be determined by the discounted price applicable to such Share
Termination Delivery Units. In the case of a Registration Settlement of Share Termination Delivery Units that are Restricted Shares (as defined below) as set forth in paragraph (k)(ii) below, the Share Termination Unit Price shall be the Settlement
Price on the Merger Date, the Tender Offer Date, the Announcement Date (in the case of a Nationalization, Insolvency or Delisting), the date of cancellation or the Early Termination Date, as applicable.
		
	Share Termination Delivery Unit:	  	In the case of a Termination Event, Event of Default, Additional Disruption Event or Delisting, one Underlying Share or, in the case of Nationalization, Insolvency, Tender Offer
or Merger Event, a unit consisting of the number or amount of each type of property received by a holder of one Underlying Share (or, if no Underlying Shares are then outstanding, the number or amount of each type of property as would have been
received by a holder of one Underlying Share had an Underlying Share been outstanding prior to the relevant transaction or event), without consideration of any requirement to pay cash or other consideration in lieu of fractional amounts of any
securities, in such Nationalization, Insolvency, Tender Offer or Merger Event. If such Nationalization, Insolvency, Tender Offer or Merger Event involves a choice of consideration to be received by holders, such holder shall be deemed to have
elected to receive the maximum possible amount of cash.

  
 19 

			
	Failure to Deliver:	  	Inapplicable
		
	Other Applicable Provisions:	  	If Share Termination Alternative is applicable, the provisions of Sections 9.9, 9.11, 9.12 and 10.5 (as modified above) of the Equity Definitions will be applicable as if
Physical Settlement were applicable, except that (i) Section 9.9 of the Equity Definitions shall be amended by replacing the word “party” in the second line thereof with the word “Seller” and deleting the remainder of the
provision and (ii) Section 10.5 shall be amended by replacing the word “party” in the third line thereof with the word “Buyer” and deleting the remainder of the provision.

  

	 	(k)	Registration/Private Placement Procedures. If, based on advice of counsel, following any delivery of Underlying Shares or Share Termination Delivery
Property to Bank hereunder, such Underlying Shares or Share Termination Delivery Property would be in the hands of Bank subject to any applicable restrictions with respect to any registration or qualification requirement or prospectus delivery
requirement for such Underlying Shares or Share Termination Delivery Property pursuant to any applicable federal or state securities law (including, without limitation, any such requirement arising under Section 5 of the Securities Act as a
result of such Underlying Shares or Share Termination Delivery Property being “restricted securities”, as such term is defined in Rule 144 under the Securities Act, or as a result of the sale of such Underlying Shares or Share Termination
Delivery Property being subject to paragraph (c) of Rule 145 under the Securities Act) (such Underlying Shares or Share Termination Delivery Property, “Restricted Shares”), then delivery of such Restricted Shares shall be
effected pursuant to either clause (i) or (ii) below at the election of Company, unless Bank waives the need for registration/private placement procedures set forth in (i) and (ii) below. Notwithstanding the foregoing, solely in
respect of any Daily Number of Warrants exercised or deemed exercised on any Expiration Date, Company shall elect, prior to the first Settlement Date for the first Expiration Date, a Private Placement Settlement or Registration Settlement for all
deliveries of Restricted Shares for all such Expiration Dates which election shall be applicable to all Settlement Dates for such Warrants and the procedures in clause (i) or clause (ii) below shall apply for all such delivered Restricted
Shares on an aggregate basis commencing after the final Settlement Date for such Warrants. The Calculation Agent shall make reasonable adjustments to settlement terms and provisions under this Confirmation to reflect a single Private Placement or
Registration Settlement for such aggregate Restricted Shares delivered hereunder. 

  

	 	(i)	 If Company elects to settle the Transaction pursuant to this clause (i) (a “Private Placement Settlement”), then delivery of
Restricted Shares by Company shall be effected in customary private placement procedures with respect to such Restricted Shares of similar size, in form and substance reasonably acceptable to Bank, in its good faith and commercially reasonable
discretion; provided that Company may not elect a Private Placement Settlement if, on the date of its election, it has taken, or caused to be taken, any action that would make unavailable either the exemption pursuant to Section 4(2) of
the Securities Act for the sale by Company to Bank (or any affiliate designated by Bank) of the Restricted Shares or the exemption pursuant to Section 4(1) or Section 4(3) of the Securities Act for resales of the Restricted Shares by Bank
(or any such affiliate of Bank). The Private Placement Settlement of such Restricted Shares shall include customary representations, covenants, blue sky and other governmental filings and/or registrations, indemnities to Bank, due diligence rights
(for Bank or any designated buyer of the Restricted Shares by Bank), opinions and certificates, and such other 

  
 20 

	 	 
documentation as is customary for private placement agreements of its size, all reasonably acceptable to Bank. In the case of a Private Placement Settlement, Bank shall, in a commercially
reasonable manner, determine the appropriate discount to the Share Termination Unit Price (in the case of settlement of Share Termination Delivery Units pursuant to paragraph (j) above) or any Settlement Price (in the case of settlement of
Underlying Shares pursuant to Section 2 above) applicable to such Restricted Shares in a commercially reasonable manner and appropriately adjust the number of such Restricted Shares to be delivered to Bank hereunder; provided that in no
event shall such number be greater than two times the Number of Shares (the “Maximum Amount”). Notwithstanding the Agreement or this Confirmation, the date of delivery of such Restricted Shares shall be the Exchange Business Day
following notice by Bank to Company, of such applicable discount and the number of Restricted Shares to be delivered pursuant to this clause (i). For the avoidance of doubt, delivery of Restricted Shares shall be due as set forth in the previous
sentence and not be due on the Share Termination Payment Date (in the case of settlement of Share Termination Delivery Units pursuant to paragraph (j) above) or on the Settlement Date for such Restricted Shares (in the case of settlement in
Underlying Shares pursuant to Section 2 above). 

 In the event Company shall not have delivered the full
number of Restricted Shares otherwise applicable as a result of the proviso above relating to the Maximum Amount (such deficit, the “Deficit Restricted Shares”), Company shall be continually obligated to deliver, from time to time
until the full number of Deficit Restricted Shares have been delivered pursuant to this paragraph, Restricted Shares when, and to the extent, that (i) Underlying Shares are repurchased, acquired or otherwise received by Company or any of its
subsidiaries after the Trade Date (whether or not in exchange for cash, fair value or any other consideration), (ii) authorized and unissued Underlying Shares reserved for issuance in respect of other transactions prior to such date which prior
to the relevant date become no longer so reserved and (iii) Company additionally authorizes any unissued Underlying Shares that are not reserved for other transactions. Company shall immediately notify Bank of the occurrence of any of the
foregoing events (including the number of Underlying Shares subject to clause (i), (ii) or (iii) and the corresponding number of Restricted Shares to be delivered) and promptly deliver such Restricted Shares thereafter. 

 

	 	(ii)	 If Company elects to settle the Transaction pursuant to this clause (ii) (a “Registration Settlement”), then Company shall
promptly (but in any event no later than the beginning of the Resale Period) file and use its good faith and reasonable best efforts to make effective under the Securities Act a registration statement or supplement or amend an outstanding
registration statement in form and substance reasonably satisfactory to Bank, to cover the resale of such Restricted Shares in accordance with customary resale registration procedures, including covenants, conditions, representations, underwriting
discounts (if applicable), commissions (if applicable), indemnities due diligence rights, opinions and certificates, and such other documentation as is customary for equity resale underwriting agreements, all reasonably acceptable to Bank. If Bank,
in its sole reasonable discretion, is not satisfied with such procedures and documentation Private Placement Settlement shall apply. If Bank is satisfied with such procedures and documentation, it shall sell the Restricted Shares pursuant to such
registration statement during a period (the “Resale Period”) commencing on the Exchange Business Day following delivery of such Restricted Shares (which, for the avoidance of doubt, shall be (x) the Share Termination Payment
Date in case of settlement in Share Termination Delivery Units pursuant to paragraph (j) above or (y) the Settlement Date in respect of the final Expiration Date for all Daily Number of Warrants) and ending on the earliest of (i) the
Exchange Business Day on which Bank completes the sale of all Restricted Shares or, in the case of settlement of Share Termination Delivery Units, a sufficient number of Restricted Shares so that the realized net proceeds of such sales equals or
exceeds the Payment Obligation (as defined above), (ii) the date upon which all Restricted Shares have been sold or transferred pursuant to Rule 144 (or similar provisions then in force) or

  
 21 

	 	 
Rule 145(d)(1) or (2) (or any similar provision then in force) under the Securities Act and (iii) the date upon which all Restricted Shares may be sold or transferred by a non-affiliate
pursuant to Rule 144 (or any similar provision then in force) or Rule 145(d)(3) (or any similar provision then in force) under the Securities Act. If the Payment Obligation exceeds the realized net proceeds from such resale, Company shall transfer
to Bank by the open of the regular trading session on the Exchange on the Exchange Trading Day immediately following the last day of the Resale Period the amount of such excess (the “Additional Amount”) in cash or in a number of
Underlying Shares (“Make-whole Shares”) in an amount that, based on the Settlement Price on the last day of the Resale Period (as if such day was the “Valuation Date” for purposes of computing such Settlement Price), has a
dollar value equal to the Additional Amount. The Resale Period shall continue to enable the sale of the Make-whole Shares. If Company elects to pay the Additional Amount in Underlying Shares, the requirements and provisions for Registration
Settlement shall apply. This provision shall be applied successively until the Additional Amount is equal to zero. In no event shall Company deliver a number of Restricted Shares greater than the Maximum Amount. 

 

	 	(iii)	Without limiting the generality of the foregoing, Company agrees that any Restricted Shares delivered to Bank, as purchaser of such Restricted Shares, (i) may be
transferred by and among Bank and its affiliates and Company shall effect such transfer without any further action by Bank and (ii) after the period of 6 months from the Trade Date (or 1 year from the Trade Date if, at such time, informational
requirements of Rule 144(c) are not satisfied with respect to the Company) has elapsed after any Settlement Date for such Restricted Shares, Company shall promptly remove, or cause the transfer agent for such Restricted Shares to remove, any legends
referring to any such restrictions or requirements from such Restricted Shares upon request by Bank (or such affiliate of Bank) to Company or such transfer agent, without any requirement for the delivery of any certificate, consent, agreement,
opinion of counsel, notice or any other document, any transfer tax stamps or payment of any other amount or any other action by Bank (or such affiliate of Bank). 

 If (x) Company shall fail to effectuate the Private Placement Settlement as set forth in clause (i) or (y) Company shall fail to effectuate the Registration Settlement as set forth in
clause (ii) and Company shall fail to effectuate the Private Placement Settlement following its failure to effectuate the Registration Settlement, then either the failure set forth in clause (x) or the failure set forth in clause
(y) shall constitute an Event of Default with respect to which Company shall be the Defaulting Party. 
  

	 	(l)	Limit on Beneficial Ownership. Notwithstanding any other provisions hereof, Bank may not exercise any Warrant hereunder or be entitled to take delivery of
any Underlying Shares deliverable hereunder, and Automatic Exercise shall not apply with respect to any Warrant hereunder, to the extent (but only to the extent) that, after such receipt of any Underlying Shares upon the exercise of such Warrant or
otherwise hereunder and after taking into account any Underlying Shares deliverable to Bank under the Base Warrant Confirmation, the Bank Group would directly or indirectly beneficially own (as such term is defined for purposes of Section 13(d)
of the Exchange Act) in excess of 9.5% of the outstanding Shares. Any purported delivery hereunder shall be void and have no effect to the extent (but only to the extent) that, after such delivery and after taking into account any Underlying Shares
deliverable to Bank under the Base Warrant Confirmation, the Bank Group would directly or indirectly so beneficially own in excess of 9.5% of the outstanding Shares. If any delivery owed to Bank hereunder is not made, in whole or in part, as a
result of this provision, Company’s obligation to make such delivery shall not be extinguished and Company shall make such delivery as promptly as practicable after, but in no event later than one Business Day after, Bank gives notice to
Company that, after such delivery, the Bank Group would not directly or indirectly so beneficially own in excess of 9.5% of the outstanding Shares. 

  
 22 

	 	(m)	Share Deliveries. Company acknowledges and agrees that, to the extent the holder of this Warrant or the holder of Warrant Shares delivered upon exercise
of this Warrant is not then an affiliate and has not been an affiliate for 90 days (it being understood that Bank will not be considered an affiliate under this paragraph solely by reason of its receipt of Warrant Shares pursuant to this Transaction
or Conversion Shares pursuant to the terms of the Warrant Shares), and otherwise satisfies all holding period and other requirements of Rule 144 of the Securities Act applicable to it, any delivery of Warrant Shares, Conversion Shares or Share
Termination Delivery Property hereunder at any time after 6 months from the Trade Date (or 1 year from the Trade Date if, at such time, informational requirements of Rule 144(c) are not satisfied with respect to the Company) shall be eligible for
resale under Rule 144 of the Securities Act and Company agrees to promptly remove, or cause the transfer agent for such Warrant Shares, Conversion Shares or Share Termination Delivery Property, to remove, any legends referring to any restrictions on
resale under the Securities Act from the Warrant Shares, Conversion Shares or Share Termination Delivery Property. Company further agrees that any delivery of Warrant Shares, Conversion Shares or Share Termination Delivery Property prior to the date
that is 6 months from the Trade Date (or 1 year from the Trade Date if, at such time, informational requirements of Rule 144(c) are not satisfied with respect to the Company), may be transferred by and among Bank and its affiliates and Company shall
effect such transfer without any further action by Bank. Notwithstanding anything to the contrary herein, Company agrees that any delivery of Warrant Shares, Conversion Shares or Share Termination Delivery Property shall be effected by book-entry
transfer through the facilities of DTC, or any successor depositary, if at the time of delivery, such class of Warrant Shares, Conversion Shares or Share Termination Delivery Property is in book-entry form at DTC or such successor depositary.
Notwithstanding anything to the contrary herein, to the extent the provisions of Rule 144 of the Securities Act or any successor rule are amended, or the applicable interpretation thereof by the Securities and Exchange Commission or any court change
after the Trade Date, the agreements of Company herein shall be deemed modified to the extent necessary, in the opinion of outside counsel of Company, to comply with Rule 144 of the Securities Act, as in effect at the time of delivery of the
relevant Warrant Shares, Conversion Shares or Share Termination Delivery Property. 

  

	 	(n)	Governing Law. New York law (without reference to choice of law doctrine other than Title 14 of Article 5 of the New York General Obligations Law).

  

	 	(o)	Waiver of Jury Trial. Each party waives, to the fullest extent permitted by applicable law, any right it may have to a trial by jury in respect of any
suit, action or proceeding relating to this Transaction. Each party (i) certifies that no representative, agent or attorney of the other party has represented, expressly or otherwise, that such other party would not, in the event of such a
suit, action or proceeding, seek to enforce the foregoing waiver and (ii) acknowledges that it and the other party have been induced to enter into this Transaction, as applicable, by, among other things, the mutual waivers and certifications
provided herein. 

  

	 	(p)	Tax Disclosure. Effective from the date of commencement of discussions concerning the Transaction, Company and each of its employees, representatives, or
other agents may disclose to any and all persons, without limitation of any kind, the tax treatment and tax structure of the Transaction and all materials of any kind (including opinions or other tax analyses) that are provided to Company relating
to such tax treatment and tax structure. 

  

	 	(q)	Maximum Share Delivery. Notwithstanding any other provision of this Confirmation or the Agreement, in no event will Company be required to deliver more
than the Maximum Amount of Shares in the aggregate to Bank in connection with this Transaction after taking into account any Underlying Shares deliverable to Bank under the Base Warrant Confirmation, subject to the provisions regarding Deficit
Restricted Shares. 

  

	 	(r)	 Right to Extend. Bank may postpone, in whole or in part, any Expiration Date or any other date of valuation or delivery with respect to
some or all of the relevant Warrants (in which event the Calculation Agent shall make appropriate adjustments to the Daily Number of Warrants with respect to one or more Expiration Dates) if Bank determines, in its commercially reasonable judgment,
that such extension is reasonably necessary or appropriate to preserve Bank’s hedging or hedge unwind activity hereunder in light of existing liquidity conditions or to enable Bank to

  
 23 

	 	 
effect purchases of Shares in connection with its hedging, hedge unwind or settlement activity hereunder in a manner that would, if Bank were Issuer or an affiliated purchaser of Issuer, be in
compliance with applicable legal, regulatory or self-regulatory requirements, or with related policies and procedures applicable to Bank. 

  

	 	(s)	Status of Claims in Bankruptcy. Bank acknowledges and agrees that this Confirmation is not intended to convey to Bank rights against Company with respect
to the Transaction that are senior to the claims of common stockholders of Company in any U.S. bankruptcy proceedings of Company; provided that nothing herein shall limit or shall be deemed to limit Bank’s right to pursue remedies in the
event of a breach by Company of its obligations and agreements with respect to the Transaction; provided, further, that nothing herein shall limit or shall be deemed to limit Bank’s rights in respect of any transactions other than
the Transaction. 

  

	 	(t)	Securities Contract; Swap Agreement. Each of Bank and Company agrees and acknowledges that Bank is a “financial institution,” “swap
participant” and “financial participant” within the meaning of Sections 101(22), 101(53C) and 101(22A) of the Bankruptcy Code. The parties hereto further agree and acknowledge (A) that this Confirmation is (i) a
“securities contract,” as such term is defined in Section 741(7) of the Bankruptcy Code, with respect to which each payment and delivery hereunder is a “settlement payment,” as such term is defined in Section 741(8) of
the Bankruptcy Code, and (ii) a “swap agreement,” as such term is defined in Section 101(53B) of the Bankruptcy Code, with respect to which each payment and delivery hereunder is a “transfer,” as such term is defined in
Section 101(54) of the Bankruptcy Code, and (B) that Bank is entitled to the protections afforded by, among other sections, Sections 362(b)(6), 362(b)(17), 546(e), 546(g), 555 and 560 of the Bankruptcy Code. 

 

	 	(u)	Delivery or Receipt of Cash. For the avoidance of doubt, other than receipt of the Premium by Company, nothing in this Confirmation shall be interpreted
as requiring Company to deliver or receive cash in respect of the settlement of the Transactions contemplated by this Confirmation, except in circumstances where the cash settlement thereof is within Company’s control (including, without
limitation, where Company elects to deliver or receive cash or fails timely to elect to deliver or receive Share Termination Delivery Property in respect of the settlement of such Transactions or in those circumstances in which holders of the Shares
would also receive cash). 

  

	 	(v)	Payment by Bank. In the event that (a) an Early Termination Date occurs or is designated with respect to the Transaction as a result of a Termination
Event or an Event of Default (other than an Event of Default arising under Section 5(a)(ii) or 5(a)(iv) of the Agreement) and, as a result, Bank owes to Company an amount calculated under Section 6(e) of the Agreement, or (b) Bank
owes to Company, pursuant to Section 12.7 or Section 12.9 of the Equity Definitions, an amount calculated under Section 12.8 of the Equity Definitions, such amount shall be deemed to be zero. 

 

	 	(w)	 Early Unwind. In the event the sale of the “Option Securities” (as defined in the Underwriting Agreement) is not consummated
with the Underwriters for any reason, or Company fails to deliver to Bank opinions of counsel as required pursuant to Section 9(a), in each case by 5:00 p.m. (New York City time) on the Premium Payment Date, or such later date as agreed upon by
the parties (the Premium Payment Date or such later date, the “Early Unwind Date”), the Transaction shall automatically terminate (the “Early Unwind”) on the Early Unwind Date and (i) the Transaction and all of
the respective rights and obligations of Bank and Company under the Transaction shall be cancelled and terminated and (ii) each party shall be released and discharged by the other party from and agrees not to make any claim against the other
party with respect to any obligations or liabilities of the other party arising out of and to be performed in connection with the Transaction either prior to or after the Early Unwind Date; provided that Company shall purchase from Bank on
the Early Unwind Date all Shares purchased by Bank or one or more of its affiliates in connection with the Transaction at the then prevailing market price. Each of Bank and Company represents and acknowledges to the other that, subject to the
proviso included in this Section 9(w), upon an Early Unwind, all obligations with respect to the Transaction shall be deemed fully and finally discharged. 

  
 24 

	 	(x)	Stockholder Approval. Company will use its best efforts to hold a special meeting of its stockholders as soon as practicable, but not later than
June 1, 2012 (the “Approval Deadline”), at which Company will seek to obtain the requisite stockholder approvals for (i) an amendment to Company’s Restated Certificate of Incorporation to increase the number of
authorized but unissued Shares to at least 31,525,169 Shares and (ii) authorization of the conversion and settlement of the Underlying Shares in accordance with NASDAQ Stock Market Rule 5635. If Company fails to obtain such stockholder
approvals by the Approval Deadline, Company will (i) continue to seek to obtain such approvals at each subsequent annual meeting of its stockholders and (ii) hold at least one special meeting of its stockholders in each calendar year,
beginning with the 2012 calendar year, at which Company will seek to obtain such approvals, in each case, until such approvals have been obtained. If such approvals have not been obtained prior to any Settlement Date hereunder, Company will issue
the relevant Underlying Shares on such Settlement Date by book-entry transfer through the facilities of DTC. 

[Remainder Intentionally Blank] 

  
 25 

 Company hereby agrees (a) to check this Confirmation carefully and immediately upon
receipt so that errors or discrepancies can be promptly identified and rectified and (b) to confirm that the foregoing (in the exact form provided by Bank) correctly sets forth the terms of the agreement between Bank and Company with respect to
the Transaction, by manually signing this Confirmation or this page hereof as evidence of agreement to such terms and providing the other information requested herein and immediately returning an executed copy to Equity Derivatives Documentation
Department, Facsimile No. (212) 428-1980/83. 
  

			
	 Very truly yours,
  

Goldman, Sachs & Co.

		
	By:	 	/s/ Goldman Sachs
	Authorized Signatory
	Name: Goldman Sachs

 Accepted and confirmed

 as of the Trade Date: 
  

			
	NuVasive, Inc.
		
	By:	 	/s/ Michael Lambert
	Authorized Signatory
	Name: Michael Lambert

[Additional Warrant Confirmation for GS] 

 Annex A 

Summary Terms of the Series A Participating Preferred Stock 

The summary below describes the principal terms of the Series A Participating Preferred Stock to be issued in connection with the
Transaction evidenced by the Confirmation (the “Confirmation”) to which this Annex A is attached (the “Warrant Transaction”). The description below is subject to, and qualified in its entirety by, the Certificate of
Designations for the Series A Participating Preferred Stock (the “Certificate of Designations”), which, upon the Premium Payment Date, shall supersede such description in its entirety. Capitalized terms used in this Annex A that are
not otherwise defined shall have the meanings set forth in the Confirmation. 
  

			
	Issuer	  	Company
		
	Securities	  	Initially, a number of shares of a series of the Company’s preferred stock, par value $0.001 per share, designated pursuant to Article IV of the Company’s Restated
Certificate of Incorporation (the “Certificate of Incorporation”) as the Series A Participating Preferred Stock (the “Preferred Stock”), which will have the rights and preferences, including the conversion,
dividend, liquidation and voting rights, described below. That number will be equal to 1/10th of the number of shares of the Company’s common stock, par value $0.001 per share (“Common Stock”) into which the Preferred Stock is
initially convertible as described below. Each share of Preferred Stock will initially be subject to conversion as described below into 20 shares of the Company’s common stock, par value $0.001 per share (the “Common Stock”).
The number of shares of Common Stock into which each share of Preferred Stock is convertible is referred to as the “Conversion Rate” and shall be subject to adjustment as set forth under “Conversion Rate Adjustments”
below.
		
	Liquidation Amount	  	$648.20 per share of Preferred Stock.
		
	Dividend Payment Dates	  	 January 1, April 1, July 1 and October 1 of each year.

 
 Notwithstanding the foregoing and for the avoidance of doubt, on the same date that
the Company pays any dividend or distribution on shares of its Common Stock (irrespective of whether such date is a Dividend Payment Date as defined above), the Company will pay a corresponding dividend or distribution, on an as-converted basis, to
holders of the Preferred Stock. Any such dividends (including extraordinary cash dividends or distributions) paid on the Preferred Stock pursuant to the immediately preceding sentence are referred to as “Paid-Through
Dividends.”

  

			
		
	Dividend Period	  	For each share of Preferred Stock, the period commencing on, and including, the immediately preceding Dividend Payment Date for such share of Preferred Stock (or if no Dividend
Payment Date has occurred for such share of Preferred Stock, the period commencing on, and including, the date of issuance of such share of Preferred Stock), and ending on, and including, the day immediately preceding the next succeeding Dividend
Payment Date.
		
	Stockholder Approvals	  	 The Company will use its best efforts to hold a special meeting of its stockholders as soon as practicable, but not later than the
Approval Deadline set forth below, at which the Company will seek to obtain the requisite stockholder approvals for (i) an amendment to Company’s Restated Certificate of Incorporation to increase the number of authorized but unissued shares of
its Common Stock to at least 31,525,169 shares of Common Stock and (ii) authorization of the conversion and settlement of the Preferred Stock in accordance with NASDAQ Stock Market Rule 5635. If the Company fails to obtain such stockholder approvals
by the Approval Deadline, the Company will (i) continue to seek to obtain such approvals at each subsequent annual meeting of its stockholders and (ii) hold at least one special meeting of its stockholders in each calendar year, beginning with the
2012 calendar year, at which the Company will seek to obtain such approvals, in each case, until such approvals have been obtained.
  

The stockholder approvals provided above are referred to collectively as the “Stockholder Approvals,” and the date on which the Company
obtains such approvals is referred to as the “Approval Date.”

		
	Approval Deadline	  	June 1, 2012
		
	Consequences of Stockholder Approvals	  	 Subject to certain exceptions set forth in the Certificate of Designations relating to recapitalizations, reclassifications and
changes of the Common Stock, if the Company obtains the Stockholder Approvals, then:
  

•         all shares of Preferred Stock issued and outstanding on
the Approval Date will automatically convert on the first business day following the Approval Date into shares of the Company’s Common Stock at the Conversion Rate in effect on such business day; and

 

•         each share of Preferred Stock issued following the
Approval Date will automatically convert on the third business day following the date of such issuance at the Conversion Rate in effect on such third business day.
  

The date on which a share of Preferred Stock is converted as set forth above is referred to as the “Conversion
Date.”

  

  
 28 

			
		  	 Each share of Preferred Stock will cease to exist on the Conversion Date relating to such share of Preferred Stock and, subject to
the requirements of Delaware law, will resume the status of an authorized and unissued share of the Company’s preferred stock, and all other rights of the holder of such share of Preferred Stock will terminate, as of the close of business on
such Conversion Date.
  
 If the Company obtains the Stockholder Approvals
after the Approval Deadline, in addition to the Common Stock issuable upon conversion of each share of Preferred Stock at the Conversion Rate, on the Conversion Date, the Company will pay to the holder to whom it delivers the shares of its Common
Stock due upon conversion cash dividends in an amount (the “Dividend Amount”) equal to all accrued and unpaid dividends on such share of Preferred Stock (including, if applicable as described opposite the heading
“—Dividends” below, dividends on such dividends), whether or not declared prior to such Conversion Date, for the then-current Dividend Period (or portion thereof) ending on such Conversion Date and all prior Dividend Periods, if any
(other than previously declared dividends on such share of Preferred Stock that were paid to the holder of record of such share of Preferred Stock as of a prior date) to the extent the Company is lawfully permitted to pay such dividends under
Delaware law. The Company may elect to satisfy its obligation to pay the Dividend Amount through the delivery of shares of Common Stock, in which case the Company will deliver to such holder a number of shares of its Common Stock equal to the
quotient of (i) the Dividend Amount, divided by (ii) the last reported sale price of the Common Stock on the second trading day immediately preceding the Conversion Date, rounded down to the nearest whole share.

		
	Blocker	  	Notwithstanding any other provision of the Certificate of Designations, no holder of Preferred Stock will have the right to acquire shares of Common Stock upon conversion of any
share or shares of Preferred Stock under the Certificate of Designations or be entitled to take delivery of any shares of Common Stock deliverable thereunder, to the extent (but only to the extent) that, after such receipt of any shares of Common
Stock upon the conversion of such share of shares or otherwise thereunder, such holder would directly or indirectly beneficially own (as such term is defined for purposes of Section 13 or Section 16 of the Exchange Act and rules promulgated
thereunder) in excess of 4.9% of the then outstanding shares of Common Stock (the “Threshold Number of Shares”). Any purported delivery thereunder shall be void and have no effect to the extent (but only to the extent) that, after
such

  

  
 29 

			
		  	delivery, such holder would directly or indirectly so beneficially own in excess of the Threshold Number of Shares. If any delivery owed to any holder thereunder is not made, in
whole or in part, as a result of this paragraph, the Company’s obligation to make such delivery shall not be extinguished and the Company shall make such delivery as promptly as practicable after, but in no event later than one business day
after, such Holder gives notice to the Company that, after such delivery, such Holder would not directly or indirectly so beneficially own in excess of the Threshold Number of Shares.
		
	Conversion Rate Adjustments	  	 The Conversion Rate will be subject to adjustment in accordance with the Certificate of Designations for the following
transactions:
  

•         the issuance by the Company of its Common Stock as a
dividend or distribution to all or substantially all holders of its Common Stock, or a subdivision or combination (including, without limitation, a reverse stock split) of its Common Stock;

 

•         the issuance by the Company to all or substantially all
holders of its Common Stock of rights, options or warrants entitling them for a period expiring 60 days or less from the date of issuance of such rights, options or warrants to subscribe for or purchase shares of the Company’s Common Stock at
less than the current market price per share of Common Stock as of the announcement date for such issuance;
  

•         the Company’s payment of a dividend or other
distribution to all or substantially all holders of its Common Stock of shares of its capital stock (other than its Common Stock) or evidences of its indebtedness or its assets (excluding (x) any dividend, distribution or issuance as to which an
adjustment was effected pursuant to the first or second bullet above or the fifth or sixth bullet below and (y) “spin-offs” as to which the fourth bullet below applies);

 

•         the Company’s payment of a dividend or other
distribution to all or substantially all holders of its Common Stock where such payment consists of shares of the Company’s capital stock of, or similar equity interests in, a subsidiary or other business unit of the Company (i.e., a spin-off)
that are, or, when issued, will be traded on a U.S. national securities exchange;

  

  
 30 

			
		  	 •       the Company’s payment of a distribution
consisting exclusively of cash to all or substantially all holders of its Common Stock, excluding (a) any cash that is distributed as part of a distribution referred to in the third bullet above and (b) any consideration payable in connection with a
tender or exchange offer made by the Company or any of its subsidiaries as to which an adjustment was effected in the sixth bullet below; and
  

•       the purchase by the Company or one or more of its subsidiaries of the
Company’s Common Stock pursuant to a tender offer or exchange offer and the cash and value of any other consideration included in the payment per share of the Company’s Common Stock validly tendered or exchanged exceeds a specified price
per share.
  
 Notwithstanding the foregoing, without prejudice to the right
to receive Paid-Through Dividends as set forth above, no adjustment will be made for any of the transactions described in the first five bullets above to the extent (but only to the extent) such dividend or distribution is paid to all holders of
Preferred Stock on an as-converted basis.

		
	Conversion Upon Reorganization Event	  	If, after the date of original issuance of the Preferred Stock, (1) there occurs (A) any consolidation or merger of the Company with or into another corporation or another
entity; (B) any sale, transfer, lease or conveyance to another corporation or another entity of the property of the Company as an entirety or substantially as an entirety; or (C) any statutory exchange of securities of the Company with another
corporation or another entity or any binding share exchange which reclassifies or changes its outstanding Common Stock (other than a change in par value, or from par value to no par value, or from no par value to par value, or as a result of a
transaction that is subject to Conversion Rate Adjustments) (any such event in clauses (A) through (C), inclusive, a “Reorganization Event”); and (2) pursuant to such Reorganization the Common Stock is converted into or exchanged
for, or constitutes solely the right to receive, cash, securities or other property, then, immediately after the effective time of such Reorganization Event, the Company shall make provision for each outstanding share of the Preferred Stock to be
converted, out of funds legally available therefor, into the kind and amount of cash, securities or other property (collectively, “Reference Property”) receivable pursuant to such Reorganization Event by a holder (the
“Representative Holder”) of a number of shares of Common Stock equal to the Conversion Rate in effect at such effective time, which holder (A) is not a person with which the Company consolidated or into which the Company merged or
which merged into the Company or to which such sale,

  

  
 31 

			
		  	transfer, lease or conveyance was made, as the case may be (any such person, a “Constituent Person”), or an affiliate of a Constituent Person, to the extent such
Reorganization Event provides for different treatment of Common Stock held by affiliates of the Company and non-affiliates, and (B) failed to exercise his rights of election, if any, as to the kind or amount of such Reference Property
(provided that if the kind or amount of such Reference Property is not the same for each share of Common Stock held by a Person (other than a Constituent Person or an affiliate thereof) who has not exercised such rights of election
(“Non-Electing Share”), then for the purposes hereunder, the kind and amount of Reference Property in respect of each Non-Electing Share shall be deemed to be the weighted average of the kinds and amounts of Reference Property
receivable per share of Common Stock pursuant to such Reorganization Event in respect of all Non-Electing Shares). On and after the effective time of a Reorganization Event, each outstanding share of the Preferred Stock shall cease to be
outstanding, dividends on such share shall cease to accrue, and all rights of the holder(s) of such share shall terminate with respect to such share, other than the right to receive the kind and amount of Reference Property into which such share of
the Preferred Stock has been converted.
		
	Dividends—Paid-Through Dividends	  	From, and including, the date of original issuance of the Preferred Stock to, but excluding, the date on which all shares of Preferred Stock underlying the Warrant Transaction
have been issued and converted into shares of Company’s common stock, the Company’s board of directors (or a duly authorized committee thereof) may not declare or pay any dividend or make any distribution (including, but not limited to,
regular quarterly cash dividends) in respect of the Company’s Common Stock, whether payable in cash, securities or any other form of property or assets, unless the board of directors (or a duly authorized committee thereof) declares and pays to
the holders of the Preferred Stock then outstanding, at the same time (irrespective of whether or not such time is a Dividend Payment Date for the Preferred Stock) and on the same terms as holders of the Company’s Common Stock, a dividend per
share of outstanding Preferred Stock then outstanding equal to the product of (i) any dividend or distribution, as applicable, declared and paid or made in respect of each share of the Company’s Common Stock and (ii) the then-current Conversion
Rate of the Preferred Stock.
		
	Dividends—Missed-Deadline Dividends	  	For each Dividend Period for a share of Preferred Stock from, and including, the Dividend Period during which the Approval Deadline occurs, or, if later, the Dividend Period
commencing on the issuance of such share, cumulative cash dividends will be payable on each

  

  
 32 

			
		  	outstanding share of Preferred Stock, when, as and if declared by the Company’s board of directors or any duly authorized committee thereof out of assets legally available
therefor, in an amount equal to the product of the Conversion Rate, the Relevant Rate and the Average Stock Price (as defined below) for such Dividend Period. Such cumulative cash dividends will compound on each Dividend Payment Date from, and
including, the Dividend Payment Date corresponding to the first Dividend Period during which dividends accumulate (i.e., no dividends will accrue on such cumulative cash dividends unless and until the first Dividend Payment Date following the
Approval Deadline has passed without such cumulative cash dividends having been paid on such date). “Average Stock Price” for any Dividend Period means the average of the last reported sale prices of the Common Stock during the five
trading day period ending on, and including, the date that is one month immediately preceding the last day of such Dividend Period (or, if such date is not a trading day, the immediately succeeding date that is a trading day). For the avoidance of
doubt, no dividends shall accrue on any share of Preferred Stock prior to the issuance of such share.
		
	Relevant Rate	  	 •         from, and including, June 1, 2012 to,
and including, September 30, 2012, 10% per annum;
  
 •         from, and including, October 1, 2012 to, and including, March 31, 2013, 12% per annum;

 

•         from, and including, April 1, 2013 to, and including,
September 30, 2013, 14% per annum; and
  
 •         thereafter, 16% per annum.

		
	Ranking	  	 The Preferred Stock, with respect to dividend rights or rights upon the Company’s liquidation, winding-up or dissolution, will
rank:
  

•         senior to the Company’s Common Stock and to each
other class of capital stock or series of preferred stock established after the date of original issuance of the Preferred Stock, the terms of which do not expressly provide that such class or series ranks senior to or on a parity with the Preferred
Stock as to dividend rights and/or rights upon the Company’s liquidation, dissolution or winding-up (which is referred to collectively as “junior stock”);

  

  
 33 

			
		  	 •         equally with each class of capital
stock or series of preferred stock established after the date of original issuance of the Preferred Stock, the terms of which expressly provide that such class or series ranks equally with the Preferred Stock as to dividend rights and/or rights upon
the Company’s liquidation, dissolution or winding-up, without regard to whether dividends accrue cumulatively or non-cumulatively (which is referred to collectively as “parity stock”);

 

•         junior to each class of capital stock or series of
preferred stock established after the date of original issuance of the Preferred Stock, the terms of which expressly provide that such class or series ranks senior to the Preferred Stock as to dividend rights and/or rights upon the Company’s
liquidation, dissolution or winding-up; and
  
 •         junior to the Company’s and its subsidiaries’ existing and future indebtedness (including, in the case of such subsidiaries, trade
payables).

		
	Dividend Stopper	  	 Subject to certain exceptions as set forth in the Certificate of Designations, so long as any share of the Preferred Stock remains
outstanding:
  

•         no dividend or distribution will be declared or paid on
the Company’s Common Stock or any other shares of junior stock (other than dividends payable solely in shares of the Company’s Common Stock) or parity stock; and

 

•         no Common Stock, junior stock or parity stock will be,
directly or indirectly, purchased, redeemed or otherwise acquired for consideration by the Company or any of its subsidiaries;
  

in each case, unless all accrued and unpaid dividends for all past Dividend Periods for the Preferred Stock, including the latest completed Dividend
Period for the Preferred Stock (including, if applicable, dividends on such dividends), on all outstanding shares of Preferred Stock have been or are contemporaneously declared and paid in full (or have been declared and a sum sufficient for the
payment thereof has been set aside for the benefit of the holders of shares of Preferred Stock on the applicable regular record date for the Preferred Stock).

		
	Voting Rights	  	The holders of Preferred Stock shall not have any voting rights except as set forth below or as otherwise from time to time required by law.
		
		  	Whenever, at any time or times, from and including the Approval Deadline, dividends payable on the shares of Preferred Stock have not been paid for an aggregate of six quarterly
Dividend Periods or more, whether or not consecutive (a “nonpayment”), the authorized number

  

  
 34 

			
		  	 of directors on the Company’s board of directors will automatically be increased by two and the holders of the Preferred Stock
will have the right, with holders of shares of any one or more other classes or series of outstanding parity stock upon which like voting rights have been conferred and are exercisable at the time, voting together as a class (and with voting rights
allocated pro rata based on the liquidation amount of each such class or series), to elect two directors (collectively, the “preferred directors” and each, a “preferred director”) to fill such newly created
directorships at the Company’s next annual meeting of stockholders (or at a special meeting called for that purpose prior to such next annual meeting by the chairman of the board or chief executive officer or holders of record of at least 10%
of (i) the Preferred Stock or (ii) any such class or series the Company’s capital stock entitled to vote for such preferred directors) and at each subsequent annual meeting of the Company’s stockholders until all accrued and unpaid
dividends for all prior Dividend Periods (including, if applicable, dividends on such dividends) have been paid in full on the Preferred Stock, at which time such right will terminate, except as otherwise provided in the Certificate of Designations
or expressly provided by law, subject to revesting in the event of each and every nonpayment; provided that it will be a qualification for election for any preferred director that the election of such preferred director will not cause the
Company to violate any corporate governance requirements of any securities exchange or other trading facility on which the Company’s securities may then be listed or traded that listed or traded companies must have a majority of independent
directors.
  
 So long as any shares of Preferred Stock are outstanding, in
addition to any other vote or consent of stockholders required by law or by the Restated Certificate of Incorporation, the vote or consent of the holders of at least
66 2/3 of the outstanding shares of Preferred Stock
at the time outstanding and entitled to vote thereon, given in person or by proxy, either in writing without a meeting or by vote at any meeting called for the purpose, shall be necessary for effecting or validating:

 

•         any amendment, alteration or repeal of any provision of
the Restated Certificate of Incorporation so as to increase the number of authorized shares of Preferred Stock or materially and adversely affect the special rights, preferences, privileges or voting powers of the Preferred Stock, taken as a whole;
or

  

  
 35 

			
		  	 •         any consummation of a binding share
exchange or reclassification involving the Preferred Stock, or of a merger or consolidation of the Company with another corporation or other entity, unless in each case either (A) such binding share exchange or reclassification constitutes a
Reorganization Event and the Corporation complies with the provisions described opposite the heading “Conversion Upon Reorganization Event” above with respect to such Reorganization Event; or (B) the shares of Preferred Stock remain
outstanding and have such rights, preferences, privileges and voting powers, and limitations and restrictions thereof, taken as a whole, as are not materially less favorable to the holders thereof than the rights, preferences, privileges and voting
powers, and limitations and restrictions thereof, of the Preferred Stock immediately prior to such consummation, taken as a whole;
  

provided, however, that for purposes of the above, any increase in the amount of the authorized or issued Preferred Stock or other authorized
preferred stock, or the creation and issuance, or an increase in the authorized or issued amount, of any other series of preferred stock or other stock of the Company ranking senior to, equally with and/or junior to the Preferred Stock with respect
to the payment of dividends (whether such dividends are cumulative or non-cumulative) and/or the distribution of assets upon liquidation, dissolution or winding up of the Company will not be deemed to materially and adversely affect the special
rights, preferences, privileges or voting powers of the Preferred Stock, taken as a whole.
  
 In addition, so long as any shares of Preferred Stock are outstanding, in addition to any other vote or consent of stockholders required by law or by the Restated Certificate of Incorporation, the vote or
consent of the holders of at a majority of the shares of Preferred Stock then outstanding, given in person or by proxy, either in writing without a meeting or by vote at any meeting called for the purpose, shall be necessary for effecting a publicly
announced tender offer by the Company of shares of Common Stock; provided, however, that such vote or consent shall not be required if the Company grants holders of Preferred Stock the right to participate, based on the number of
shares of Common Stock into which such Preferred Stock is convertible, in such tender offer on the same terms and conditions as holders of Common Stock.

		
	Liquidation Preference	  	In the event of the Company’s liquidation, dissolution or winding-up of its affairs, whether voluntary or involuntary, each holder of Preferred Stock will be entitled to
receive for each share of Preferred Stock, out

  

  
 36 

			
		  	 of the Company’s assets or proceeds thereof (whether capital or surplus) available for distribution to its stockholders, subject
to the rights of any of its creditors, before any payment or distribution of such assets or proceeds is made to or set aside for the holders of the Company’s Common Stock and any other junior stock, payment in full in an amount equal to the sum
of (a) the Liquidation Amount per share of Preferred Stock and (b) an amount equal to any accrued and unpaid dividends (including, if applicable, dividends on such amount) on each share of Preferred Stock, whether or not declared, from the relevant
date of issuance to the date fixed for liquidation, dissolution or winding-up (such amounts collectively, the “liquidation preference”).
  

If in any distribution described in the immediately preceding paragraph the Company’s assets or proceeds thereof are not sufficient to pay in full
the amounts payable with respect to all outstanding shares of Preferred Stock and the corresponding amounts payable with respect of any other stock of the Company’s ranking equally with the Preferred Stock as to such distribution, holders of
Preferred Stock and the holders of such other stock will share ratably in any such distribution in proportion to the full accrued and unpaid respective distributions to which they are entitled.

 
 If the liquidation preference has been paid in full to all holders of Preferred Stock
and the corresponding amounts payable with respect to any other stock of the Company ranking equally with the Preferred Stock as to such distribution have been paid in full, the holders of the Company’s other stock will be entitled to receive
all of the Company’s remaining assets (or proceeds thereof) according to their respective rights and preferences; provided that if the amount of such assets or proceeds to be distributed with respect to a number of shares of the
Company’s Common Stock equal to the then-current Conversion Rate (the “as-converted liquidation amount”) exceeds the liquidation preference per share of Preferred Stock, then holders of Preferred Stock will be entitled to
receive, for each share of Preferred Stock, an additional amount (the “liquidation participation amount”) out of such assets or proceeds such that the as-converted liquidation amount equals the sum of the liquidation preference,
plus the liquidation participation amount, such that the holders of Preferred Stock receive the same amount on an as-converted basis as the holders of a number of shares of the Company’s Common Stock equal to the then-current Conversion
Rate.

  

  
 37 

			
		
	Transferability; Right to Designate	  	 Each share of Preferred Stock will be fully transferable to qualified institutional buyers at the option of the holder thereof,
without the Company’s consent.
  
 In addition, notwithstanding any other
provision in the Certificate of Designation to the contrary requiring or allowing a holder of Preferred Stock to purchase, sell, receive or deliver any shares of Preferred Stock or other securities to or from the Company, such holder may designate
any of its affiliates to purchase, sell, receive or deliver such shares or other securities and otherwise to perform holder’s obligations under the Certificate of Designations and any such designee may assume such obligations. Such holder shall
be discharged of its obligations to the Company to the extent of any such performance.

		
	Registration/Private Placement Procedures	  	The Certificate of Designations will contain provisions substantially similar to the registration and private placement provisions set forth in Section 9(k) of the Confirmation
if, in the reasonable opinion of any holder of Preferred Stock, following any delivery of shares of Preferred Stock, such shares would be in the hands of such holder subject to any applicable restrictions with respect to any registration or
qualification requirement or prospectus delivery requirement for such shares pursuant to any applicable federal or state securities law (including, without limitation, any such requirement arising under Section 5 of the Securities Act of 1933, as
amended (the “Securities Act”), as a result of such shares being “restricted securities”, as such term is defined in Rule 144 under the Securities Act, or as a result of the sale of such shares or being subject to
paragraph (c) of Rule 145 under the Securities Act).
		
	Redemption	  	The Preferred Stock is not redeemable at the Company’s option at any time.
		
	Repurchase	  	The Preferred Stock is not subject to repurchase at the option of holders at any time.
		
	Preemptive Rights	  	The holders of the Preferred Stock do not have any preemptive rights.
		
	Listing	  	The Preferred Stock will not be listed on any securities exchange or any automated dealer quotation system.
		
	Transfer Agent, Etc.	  	The transfer agent, registrar, paying agent and the conversion agent for the Preferred Stock will be Computershare Trust Company, N.A.

 [Remainder of Page Intentionally Left Blank] 

  

  
 38Indenture

 Exhibit 4.1 
 EXECUTION VERSION 
  

 
  

NUVASIVE, INC. 
 AND 
 U.S. BANK NATIONAL ASSOCIATION 

Trustee 
  

 
 Indenture

 Dated as of June 28, 2011 
  

 
 2.75%
Convertible Senior Notes due 2017 
  
  

 

 TABLE OF CONTENTS 

 

							
	 	 	 	  	PAGE	 
	
	ARTICLE 1	  
	DEFINITIONS AND INCORPORATION BY REFERENCE	  
			
	 Section 1.01.
	 	 Definitions
	  	 	1	  
	 Section 1.02.
	 	 Trust Indenture Act Provisions
	  	 	10	  
	 Section 1.03.
	 	 Rules of Construction
	  	 	10	  
	
	 ARTICLE 2
	   

	THE NOTES	  
			
	 Section 2.01.
	 	 Designation and Amount
	  	 	11	  
	 Section 2.02.
	 	 Form and Dating
	  	 	11	  
	 Section 2.03.
	 	 Execution and Authentication; Payments of Interest and Defaulted Amounts
	  	 	13	  
	 Section 2.04.
	 	 Registrar, Paying Agent and Conversion Agent
	  	 	15	  
	 Section 2.05.
	 	 Paying Agent to Hold Money in Trust
	  	 	15	  
	 Section 2.06.
	 	 Transfer and Exchange
	  	 	16	  
	 Section 2.07.
	 	 Replacement Notes
	  	 	17	  
	 Section 2.08.
	 	 Outstanding Notes
	  	 	17	  
	 Section 2.09.
	 	 Treasury Notes
	  	 	18	  
	 Section 2.10.
	 	 Temporary Notes
	  	 	18	  
	 Section 2.11.
	 	 Cancellation; Repurchase
	  	 	18	  
	 Section 2.12.
	 	 Additional Transfer and Exchange Requirements
	  	 	19	  
	 Section 2.13.
	 	 CUSIP Numbers
	  	 	21	  
	
	ARTICLE 3	  
	NO REDEMPTION; REPURCHASE UPON A FUNDAMENTAL
CHANGE	  
			
	 Section 3.01.
	 	 No Optional Redemption
	  	 	21	  
	 Section 3.02.
	 	 Repurchase At Option of The Holder Upon A Fundamental Change
	  	 	21	  
	 Section 3.03.
	 	 Compliance With Securities Laws Upon Purchase of Notes
	  	 	23	  
	 Section 3.04.
	 	 No Repurchase Upon Acceleration
	  	 	23	  
	 Section 3.05.
	 	 Repayment to the Company
	  	 	24	  
	 Section 3.06.
	 	 Partial Repurchase
	  	 	24	  
	
	ARTICLE 4	  
	CONVERSION	  
			
	 Section 4.01.
	 	 Conversion Rights
	  	 	24	  
	 Section 4.02.
	 	 Settlement Upon Conversion; Conversion Procedures
	  	 	26	  
	 Section 4.03.
	 	 Company to Provide Stock
	  	 	31	  
	 Section 4.04.
	 	 Adjustment to Conversion Rate Upon a Make-Whole Fundamental Change
	  	 	31	  
	 Section 4.05.
	 	 Conversion Rate Adjustments
	  	 	33	  

							
	 Section 4.06.
	  	 Adjustments of Prices
	  	 	41	  
	 Section 4.07.
	  	 Effect of Recapitalizations, Reclassifications and Changes of the Common Stock
	  	 	41	  
	 Section 4.08.
	  	 Conversion of Beneficial Interests in Global Notes
	  	 	43	  
	 Section 4.09.
	  	 Stockholders Rights
	  	 	43	  
	 Section 4.10.
	  	 Trustee’s Disclaimer
	  	 	43	  
	
	ARTICLE 5	  
	COVENANTS	  
			
	 Section 5.01.
	  	 Payment on the Notes
	  	 	44	  
	 Section 5.02.
	  	 SEC Reports
	  	 	44	  
	 Section 5.03.
	  	 Compliance Certificates
	  	 	45	  
	 Section 5.04.
	  	 Further Instruments and Acts
	  	 	45	  
	 Section 5.05.
	  	 Maintenance of Corporate Existence
	  	 	45	  
	 Section 5.06.
	  	 Stay, Extension and Usury Laws
	  	 	45	  
	 Section 5.07.
	  	 Appointments to Fill Vacancies in Trustee’s Office
	  	 	45	  
	
	ARTICLE 6	  
	CONSOLIDATION, MERGER AND SALE OF ASSETS	  
			
	 Section 6.01.
	  	 Company May Consolidate, Etc, Only on Certain Terms
	  	 	46	  
	 Section 6.02.
	  	 Successor Substituted
	  	 	46	  
	
	ARTICLE 7	  
	DEFAULT AND REMEDIES	  
			
	 Section 7.01.
	  	 Events Of Default
	  	 	46	  
	 Section 7.02.
	  	 Acceleration
	  	 	47	  
	 Section 7.03.
	  	 Other Remedies
	  	 	48	  
	 Section 7.04.
	  	 Extension Fee
	  	 	48	  
	 Section 7.05.
	  	 Waiver of Defaults and Events of Default
	  	 	49	  
	 Section 7.06.
	  	 Control by Majority
	  	 	49	  
	 Section 7.07.
	  	 Limitations on Suits
	  	 	49	  
	 Section 7.08.
	  	 Rights of Holders to Receive Payment and to Convert
	  	 	50	  
	 Section 7.09.
	  	 Collection Suit By Trustee
	  	 	50	  
	 Section 7.10.
	  	 Trustee May File Proofs of Claim
	  	 	50	  
	 Section 7.11.
	  	 Priorities
	  	 	50	  
	 Section 7.12.
	  	 Undertaking For Costs
	  	 	51	  
	
	ARTICLE 8	  
	TRUSTEE	  
			
	 Section 8.01.
	  	 Duties of Trustee
	  	 	51	  
	 Section 8.02.
	  	 Notice of Defaults
	  	 	52	  
	 Section 8.03
	  	 Certain Rights of Trustee
	  	 	52	  
	 Section 8.04.
	  	 Not Responsible for Issuance of Notes
	  	 	53	  
	 Section 8.05.
	  	 May Hold Notes
	  	 	53	  

  

  
 -ii-

							
	 Section 8.06.
	 	 Compensation and Reimbursement
	  	 	53	  
	 Section 8.07.
	 	 Disqualification; Conflicting Interests
	  	 	53	  
	 Section 8.08.
	 	 Corporate Trustee Required; Eligibility
	  	 	53	  
	 Section 8.09.
	 	 Reports by Trustee to Holders
	  	 	54	  
	 Section 8.10.
	 	 Resignation and Removal; Appointment of Successor
	  	 	54	  
	 Section 8.11.
	 	 Acceptance of Appointment by Successor
	  	 	55	  
	 Section 8.12.
	 	 Merger, Conversion, Consolidation or Succession to Business
	  	 	55	  
	 Section 8.13.
	 	 Preferential Collection of Claims Against Company
	  	 	55	  
	 Section 8.14.
	 	 Appointment of Authenticating Agent
	  	 	56	  
	
	ARTICLE 9	  
	SATISFACTION AND DISCHARGE OF INDENTURE	  
			
	 Section 9.01.
	 	 Satisfaction And Discharge Of Indenture
	  	 	57	  
	 Section 9.02.
	 	 Application of Trust Money and Shares of Common Stock
	  	 	58	  
	 Section 9.03.
	 	 Repayment to Company
	  	 	58	  
	 Section 9.04.
	 	 Reinstatement
	  	 	58	  
	
	ARTICLE 10	  
	AMENDMENTS, SUPPLEMENTS AND WAIVERS	  
			
	 Section 10.01.
	 	 Without Consent of Holders
	  	 	59	  
	 Section 10.02.
	 	 With Consent of Holders
	  	 	60	  
	 Section 10.03.
	 	 Compliance With TIA
	  	 	61	  
	 Section 10.04.
	 	 Revocation and Effect of Consents
	  	 	61	  
	 Section 10.05.
	 	 Notation on or Exchange of Notes
	  	 	61	  
	 Section 10.06.
	 	 Trustee to Sign Amendments, Etc.
	  	 	61	  
	
	ARTICLE 11	  
	LISTS OF HOLDERS AND REPORTS BY THE
COMPANY AND THE TRUSTEE	  

			
	 Section 11.01.
	 	 Lists of Holders
	  	 	62	  
	 Section 11.02.
	 	 Preservation and Disclosure of Lists
	  	 	62	  
	 Section 11.03.
	 	 Reports by Trustee
	  	 	62	  
	
	ARTICLE 12	  
	CONCERNING THE HOLDERS	  
			
	 Section 12.01.
	 	 Action by Holders
	  	 	62	  
	 Section 12.02.
	 	 Proof of Execution by Holders
	  	 	63	  
	 Section 12.03.
	 	 Who Are Deemed Absolute Owners
	  	 	63	  
	
	ARTICLE 13	  
	HOLDERS’ MEETINGS	  
			
	 Section 13.01.
	 	 Purpose of Meetings
	  	 	63	  
	 Section 13.02.
	 	 Call of Meetings by Trustee
	  	 	64	  
	 Section 13.03.
	 	 Call of Meetings by Company or Holders
	  	 	64	  

  
 -iii-

							
	 Section 13.04.
	  	 Qualifications for Voting
	  	 	64	  
	 Section 13.05.
	  	 Regulations
	  	 	64	  
	 Section 13.06.
	  	 Voting
	  	 	65	  
	 Section 13.07.
	  	 No Delay of Rights by Meeting
	  	 	65	  
	
	ARTICLE 14	  
	MISCELLANEOUS	  
			
	 Section 14.01.
	  	 Trust Indenture Act Controls
	  	 	66	  
	 Section 14.02.
	  	 Notices
	  	 	66	  
	 Section 14.03.
	  	 Communications by Holders With Other Holders
	  	 	66	  
	 Section 14.04.
	  	 Certificate and Opinion as to Conditions Precedent
	  	 	67	  
	 Section 14.05.
	  	 Record Date for Vote or Consent of Holders
	  	 	67	  
	 Section 14.06.
	  	 Legal Holidays
	  	 	68	  
	 Section 14.07.
	  	 Governing Law
	  	 	68	  
	 Section 14.08.
	  	 No Adverse Interpretation of Other Agreements
	  	 	68	  
	 Section 14.09.
	  	 No Personal Liability of Directors, Officers, Employees or Stockholders
	  	 	68	  
	 Section 14.10.
	  	 Successors
	  	 	68	  
	 Section 14.11.
	  	 Multiple Counterparts
	  	 	68	  
	 Section 14.12.
	  	 Separability
	  	 	68	  
	 Section 14.13.
	  	 Table of Contents, Headings, Etc.
	  	 	68	  
	 Section 14.14.
	  	 Force Majeure
	  	 	68	  
	 Section 14.15.
	  	 Waiver of Jury Trial
	  	 	69	  

 EXHIBIT 
  

							
	 Exhibit A
	    	 Form of Note
	  	 	A-1	  

  
 -iv-

 INDENTURE, dated as of June 28, 2011, between NUVASIVE, INC., a Delaware corporation
(the “Company”), having its principal office at 7475 Lusk Boulevard, San Diego, California 92121, and U.S. BANK NATIONAL ASSOCIATION, a national banking association, as Trustee (the “Trustee”). 

The Company and the Trustee agree as follows for the benefit of each other and for the equal and ratable benefit of the Holders of the
Company’s 2.75% Convertible Senior Notes due 2017 (as are issued under this Indenture, and as amended or supplemented from time to time, the “Notes”). 
 ARTICLE 1 
 DEFINITIONS AND
INCORPORATION BY REFERENCE 
 Section 1.01. Definitions.  

“Additional Shares” has the meaning set forth in Section 4.04(a). 

“Affiliate” means, with respect to any specified Person, any other Person directly or indirectly controlling or
controlled by or under direct or indirect common control with such specified Person. For the purposes of this definition, “control,” when used with respect to any Person, means the power to direct the management and policies of such
Person, directly or indirectly, whether through the ownership of voting securities, by contract or otherwise; and the terms “controlling” and “controlled” have meanings correlative to the foregoing. 

“Agent” means any Registrar, Paying Agent or Conversion Agent. 

“Agent Member” has the meaning set forth in Section 2.02(b). 

“Applicable Procedures” means, with respect to any transfer or exchange of beneficial ownership interests in a Global
Note, the rules and procedures of the Depositary, in each case to the extent applicable to such transfer or exchange. 

“Authenticating Agent” has the meaning set forth in Section 8.14(a). 

“Bankruptcy Law” means Title 11 of the United States Code (or any successor thereto) or any similar federal or state law
for the relief of debtors. 
 “Bid Solicitation Agent” means the Person appointed by the Company to solicit
bids for the Trading Price of the Notes in accordance with Section 4.01(c) and the definition of “Trading Price” below. The Trustee shall initially act as the Bid Solicitation Agent. 

“Board of Directors” means either the board of directors of the Company or any committee of the Board of Directors
authorized to act for it with respect to this Indenture. 
 “Board Resolution” means a copy of a resolution
certified by the Secretary or an Assistant Secretary of the Company to have been duly adopted by the Board of Directors and to be in full force and effect on the date of such certification, and delivered to the Trustee. 

 “Business Day” means any day other than a Saturday, a Sunday or a day on
which the Federal Reserve Bank of New York is authorized or required by law or executive order to close or be closed. 

“Capital Stock” of any Person means (a) in the case of a corporation, corporate stock of such Person, (b) in
the case of an association or business entity, shares, interests, participations, rights or other equivalents (however designated) of corporate stock of such Person, (c) in the case of a partnership or limited liability company, partnership or
membership interests (whether general or limited) of such Person and (d) in the case of any other legal form, any other interest or participation of such Person that confers the right to receive a share of the profits and losses of, or
distribution of assets of, such Person. 
 “Cash” or “cash” means such coin or currency of the
United States as at any time of payment is legal tender for the payment of public and private debts. 
 “Cash
Settlement” has the meaning set forth in Section 4.02(a). 
 “Certificated Note” means a Note
that is in substantially the form attached hereto as Exhibit A and that includes the text called for in Exhibit A for Certificated Notes. 
 “close of business” means 5:00 p.m. (New York City time). 

“Combination Settlement” has the meaning set forth in Section 4.02(a). 

“Common Stock” means the common stock of the Company, $0.001 par value per share, subject to Section 4.07.

 “Company” means the party named as such in the first paragraph of this Indenture until a Successor Company
replaces it pursuant to the applicable provisions of this Indenture, and thereafter “Company” shall mean such Successor Company. 
 “Company Order” means a written order of the Company signed by two Officers. 
 “Conversion Agent” has the meaning set forth in Section 2.04. 
 “Conversion Date” has the meaning set forth in Section 4.02(c). 
 “Conversion Notice” has the meaning set forth in Section 4.02(b). 
 “Conversion Obligation” has the meaning set forth in Section 4.01(a). 
 “Conversion Price” means at any time $1,000, divided by the Conversion Rate in effect at such time. 
 “Conversion Rate” has the meaning set forth in Section 4.01(a). 
 “Corporate Trust Office” means the office of the Trustee at U.S. Bank National Association, 100 Wall Street, Suite 1600, New York, NY 10005, Attention: Corporate Trust Services or such
other address as to which the Trustee may give notice to the Company. 

  
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 “Custodian” means any receiver, trustee, assignee, liquidator, sequestrator
or similar official under any Bankruptcy Law. 
 “Daily Conversion Value” means, for each of the 40 consecutive
Trading Days during the Observation Period, 2.5% of the product of (a) the Conversion Rate on such Trading Day and (b) the Daily VWAP on such Trading Day. 
 “Daily Measurement Value” means the Specified Dollar Amount, if any, divided by 40. 
 “Daily Settlement Amount,” for each of the 40 consecutive Trading Days during the Observation Period, shall consist of: 

(a) cash equal to the lesser of (i) the Daily Measurement Value and (ii) the Daily Conversion Value; and

 (b) to the extent that the Daily Conversion Value exceeds the Daily Measurement Value, a number of shares of
Common Stock equal to (i) the difference between the Daily Conversion Value and the Daily Measurement Value, divided by (ii) the Daily VWAP for such Trading Day. 

“Daily VWAP” means, for each of the 40 consecutive Trading Days during the applicable Observation Period, the per share
volume-weighted average price as displayed under the heading “Bloomberg VWAP” on Bloomberg page “NUVA.Q <equity> AQR” (or its equivalent successor if such page is not available) in respect of the period from the scheduled
open of trading until the scheduled close of trading of the primary trading session on such Trading Day (or if such volume-weighted average price is unavailable, the market value of one share of Common Stock on such Trading Day determined, using a
volume-weighted average method, by a nationally recognized independent investment banking firm retained for this purpose by the Company). The “Daily VWAP” shall be determined without regard to after-hours trading or any other
trading outside of the regular trading session trading hours. 
 “Default” or “default” means,
when used with respect to the Notes, any event that is or, after notice or passage of time or both, would be an Event of Default. 
 “Defaulted Amounts” means any amounts on any Notes (including, without limitation, the Fundamental Change Repurchase Price, principal and interest) that are payable but are not punctually
paid or duly provided for. 
 “Depositary” has the meaning set forth in Section 2.02(b). 

“Distributed Property” has the meaning set forth in Section 4.05(c). 

“DTC” has the meaning set forth in Section 2.02(b). 

“Event of Default” has the meaning set forth in Section 7.01. 

“Ex-Dividend Date” means the first date on which the shares of the Common Stock trade on the applicable exchange or in
the applicable market, regular way, without the right to 

  
 -3-

 
receive the issuance, dividend or distribution in question, from the Company or, if applicable, from the seller of Common Stock on such exchange or market (in the form of due bills or otherwise)
as determined by such exchange or market. 
 “Exchange Act” means the Securities Exchange Act of 1934, as
amended, and the rules and regulations promulgated thereunder, as in effect from time to time. 
 “Extension
Fee” has the meaning set forth in Section 7.04(a). 
 “Extension Right” has the meaning set forth
in Section 7.04(a). 
 A “Fundamental Change” shall be deemed to have occurred if any of the following
occurs: 
 (a) any Person files a Schedule TO, or any schedule, form or report under the Exchange Act, disclosing
that such Person has acquired beneficial ownership, directly or indirectly, through a purchase, merger or other acquisition transaction or series of transactions, of shares of the Company’s Capital Stock entitling such Person to exercise 50% or
more of the total voting power of all shares of the Company’s Capital Stock entitled to vote generally in elections of directors, other than an acquisition by the Company or any of its Subsidiaries or any of the Company’s employee benefit
plans; or 
 (b) the Company (i) merges or consolidates with or into any other Person, other than a
Subsidiary of the Company, another Person merges with or into the Company, or the Company conveys, sells, transfers or leases all or substantially all of its assets to another Person or (ii) engages in any recapitalization, reclassification or
other transaction in which all or substantially all of the Common Stock is exchanged for or converted into cash, securities or other property, in each case, other than any merger or consolidation: 

(1) that does not result in a reclassification, conversion, exchange or cancellation of the outstanding Common Stock;

 (2) pursuant to which the consideration received by holders of the Common Stock immediately prior to the
transaction entitles such holders to exercise, directly or indirectly, 50% or more of the voting power of all shares of Capital Stock entitled to vote generally in the election of directors of the continuing or surviving corporation immediately
after such transaction; or 
 (3) which is effected solely to change the Company’s jurisdiction of
incorporation and results in a reclassification, conversion or exchange of outstanding shares of Common Stock solely into shares of common stock of the surviving entity; or 

(c) the Company is liquidated or dissolved or holders of Common Stock approve any plan or proposal for the Company’s
liquidation or dissolution; or 

  
 -4-

 (d) shares of Common Stock, or shares of any other Capital Stock or American
Depositary Receipts in respect of shares of Capital Stock into which the Notes are convertible pursuant to the terms of this Indenture, are not listed for trading on any of The New York Stock Exchange, The NASDAQ Global Market or The NASDAQ Global
Select Market (or any of their respective successors), 
 provided, that the definition of Fundamental Change (and the definition of
Make-Whole Fundamental Change) shall not include a merger or consolidation under clause (a) or any event specified under clause (b), in each case, if at least 90% of the consideration paid for the Common Stock (excluding cash payments for
fractional shares and cash payments made pursuant to dissenters’ appraisal rights) in connection with such event consists of shares of common stock traded on any of The New York Stock Exchange, The NASDAQ Global Market or The NASDAQ Global
Select Market (or any of their respective successors) (or will be so traded or quoted immediately following the completion of the merger or consolidation or such other transaction) and, as a result of such transaction or transactions the Notes
become convertible into such consideration (subject to Section 4.02), pursuant to Section 4.07(a) and any supplemental indenture hereto entered into pursuant to such Section. For purposes of this definition, whether a Person is a
“beneficial owner” will be determined in accordance with Rule 13d-3 under the Exchange Act, and “Person” includes any syndicate or group that would be deemed to be a “person” under Section 13(d)(3) of the Exchange
Act. 
 “Fundamental Change Repurchase Date” has the meaning set forth in Section 3.02(a). 

“Fundamental Change Repurchase Price” has the meaning set forth in Section 3.02(a). 

“Fundamental Change Repurchase Right Notice” has the meaning set forth in Section 3.02(b). 

“GAAP” means generally accepted accounting principles in the United States of America as in effect as of the date of
this Indenture, including those set forth in (1) the opinions and pronouncements of the Accounting Principles Board of the American Institute of Certified Public Accountants, (2) the statements and pronouncements of the Financial
Accounting Standards Board, (3) such other statements by such other entity as approved by a significant segment of the accounting profession and (4) the rules and regulations of the SEC governing the inclusion of financial statements
(including pro forma financial statements) in registration statements filed under the Securities Act and periodic reports required to be filed pursuant to Section 13 of the Exchange Act, including opinions and pronouncements in staff accounting
bulletins and similar written statements from the accounting staff of the SEC. 
 “Global Note” means a Note
that is in substantially the form attached hereto as Exhibit A, including the text and schedule called for in Exhibit A for Global Notes, and that is deposited with the Depositary or the Notes Custodian and registered in the name of
the Depositary or its nominee. 
 “Holder” means the Person in whose name a Note is registered on the Primary
Registrar’s books. 

  
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 “Indenture” means this Indenture as amended or supplemented from time to
time pursuant to the terms of this Indenture. 
 “Interest Payment Date” means each January 1 and
July 1 of each year, beginning on January 1, 2012. 
 “Last Reported Sale Price” of the Common Stock
on any date means the closing sale price per share (or if no closing sale price is reported, the average of the bid and ask prices or, if more than one in either case, the average of the average bid and the average ask prices) on that date as
reported in composite transactions for the principal U.S. national or regional securities exchange on which the Common Stock is traded. If the Common Stock is not listed for trading on a U.S. national or regional securities exchange on the relevant
date, the “Last Reported Sale Price” shall be the last quoted bid price for the Common Stock in the over-the-counter market on the relevant date as reported by OTC Markets Group Inc. or a similar organization. If the Common Stock is
not so quoted, the “Last Reported Sale Price” shall be the average of the mid-point of the last bid and ask prices for the Common Stock on the relevant date from each of at least three nationally recognized independent investment
banking firms selected by the Company for this purpose. 
 “Make-Whole Fundamental Change” means any
transaction or event that constitutes a Fundamental Change (without giving effect to clause (b)(2) in the definition of “Fundamental Change” but subject to the proviso in such definition). 

“Make-Whole Reference Date” has the meaning set forth in Section 4.04(c). 

“Market Disruption Event” means (a) a failure by The NASDAQ Global Select Market or, if the Common Stock is not
then listed on The NASDAQ Global Select Market, the principal other U.S. national or regional securities exchange on which the Common Stock is then listed or, if the Common Stock is not then listed on a U.S. national or regional securities exchange,
the principal other market on which the Common Stock is then listed or admitted for trading to open for trading during its regular trading session or (b) the occurrence or existence prior to 1:00 p.m., New York City time, on any Scheduled
Trading Day for the Common Stock for more than one half-hour period in the aggregate during regular trading hours of any suspension or limitation imposed on trading (by reason of movements in price exceeding limits permitted by the relevant stock
exchange or otherwise) in the Common Stock or in any options contracts or future contracts relating to the Common Stock. 

“Maturity Date” means July 1, 2017. 
 “Measurement Period” has the meaning set forth in Section 4.01(c). 
 “Merger Event” has the meaning set forth in Section 4.07(a). 

“Minimum Stock Price” has the meaning set forth in Section 4.04(e)(iii). 

“Notes” has the meaning set forth in the second paragraph hereof. 

  
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 “Notes Custodian” means the Trustee, as custodian for DTC, with respect to
the Global Notes, or any successor thereto. 
 “Observation Period” with respect to any Note surrendered for
conversion means: (a) if the relevant Conversion Date occurs prior to January 1, 2017, the 40 consecutive Trading Day period beginning on, and including, the second Trading Day after such Conversion Date; and (b) if the relevant
Conversion Date occurs on or after January 1, 2017, the 40 consecutive Trading Days beginning on, and including, the 42nd Scheduled Trading Day immediately preceding the Maturity Date. 

“Officer” means the Chairman of the Board, the Chief Executive Officer, the President, any Vice President, the Chief
Operating Officer, the Chief Financial Officer, the Treasurer, any Assistant Treasurer, the Controller, the Secretary or any Assistant Secretary of the Company. 
 “Officers’ Certificate” means a certificate signed on behalf of the Company by two Officers that meets the requirements of Section 14.04. 

“open of business” means 9:00 a.m. (New York City time). 

“Opinion of Counsel” means a written opinion that meets the requirements of Section 14.04 from legal counsel. The
counsel may be an employee of or counsel to the Company or any Subsidiary of the Company. 
 “Paying Agent” has
the meaning set forth in Section 2.04. 
 “Person” means any individual, corporation, partnership, limited
liability company, joint venture, association, joint-stock company, trust, unincorporated organization, government or any agency or political subdivision thereof or any other entity. 

“Physical Settlement” has the meaning set forth in Section 4.02(a). 

“Preferred Stock” means the Company’s Series A Participating Preferred Stock. 

“Primary Registrar” has the meaning set forth in Section 2.04. 

“Record Date” means, with respect to any dividend, distribution or other transaction or event in which the holders of
Common Stock (or other security) have the right to receive any cash, securities or other property or in which the Common Stock (or other applicable security) is exchanged for or converted into any combination of cash, securities or other property,
the date fixed for determination of stockholders entitled to receive such cash, securities or other property (whether such date is fixed by the Board of Directors, by statute, by contract or otherwise). 

“Reference Property” has the meaning set forth in Section 4.07(a). 

“Registrar” has the meaning set forth in Section 2.04. 

  
 -7-

 “Regular Record Date,” with respect to any Interest Payment Date, shall
mean the December 15 or June 15 (whether or not such day is a Business Day) immediately preceding the applicable January 1 or July 1 Interest Payment Date, respectively. 

“Repurchase Notice” has the meaning set forth in Section 3.02(c). 

“Responsible Officer” when used with respect to the Trustee, means any officer within the corporate trust department of
the Trustee, including any vice president, assistant vice president, assistant secretary, assistant treasurer or any other officer of the Trustee who customarily performs functions similar to those performed by the Persons who at the time shall be
such officers, respectively, or to whom such matter is referred because of his or her knowledge of and familiarity with the particular subject and who shall have direct responsibility for the administration of this Indenture. 

“Scheduled Trading Day” means a day that is scheduled to be a Trading Day; provided that if the Common Stock is
not listed or admitted for trading on any U.S. national or regional securities exchange or other market, “Scheduled Trading Day” means a Business Day. 
 “SEC” means the U.S. Securities and Exchange Commission. 

“Securities Act” means the Securities Act of 1933, as amended, and the rules and regulations promulgated thereunder, as
in effect from time to time. 
 “Settlement Method” means, with respect to any conversion of the Notes,
Physical Settlement, Cash Settlement or Combination Settlement, as elected (or deemed to have been elected) by the Company. 

“Settlement Method Election Date” has the meaning set forth in Section 4.02(a)(i). 

“Significant Subsidiary” means, in respect of any Person, a Subsidiary of such Person that would constitute a
“significant subsidiary”, as such term is defined in Rule 1-02 of Regulation S-X promulgated by the SEC as in effect on the date hereof. 
 “Specified Dollar Amount” means, if Combination Settlement applies to any conversion of Notes, a dollar amount per $1,000 principal amount of Notes as specified in the notice delivered by
the Company pursuant to Section 4.02(a)(i) electing a Settlement Method (or that is deemed to have been so specified) with respect to such conversion. 
 “Spin-Off” has the meaning set forth in Section 4.05(c). 

“Stock Price” has the meaning set forth in Section 4.04(c). 

“Stockholder Approvals” means the requisite approvals from the Company’s stockholders to (i) amend its
Restated Certificate of Incorporation to sufficiently increase the number of authorized but unissued shares of Common Stock to permit (1) the conversion and settlement of all Notes into shares of Common Stock (including any additional Notes
purchased by the Underwriters pursuant to the exercise of their option to purchase additional Notes as set forth in the Underwriting Agreement) and (2) the conversion and settlement, through the delivery

  
 -8-

 
of shares of Common Stock, of the maximum number of shares of the Preferred Stock issuable upon exercise of the warrants issued by the Company to certain of the Underwriters or their Affiliates
concurrently with the issuance of the Notes and (ii) authorize such conversion and settlement of the Preferred Stock of the Company in accordance with NASDAQ Stock Market Rule 5635. 

“Subsidiary” means, in respect of any Person, any corporation, association, partnership or other business entity of
which more than 50% of the total voting power of shares of Capital Stock or other interests (including partnership interests) entitled (without regard to the occurrence of any contingency) to vote in the election of directors, managers, general
partners or trustees thereof is at the time owned or controlled, directly or indirectly, by (a) such Person; (b) such Person and one or more Subsidiaries of such Person; or (c) one or more Subsidiaries of such Person. 

“Successor Company” has the meaning set forth in Section 6.01(a). 

“TIA” means the Trust Indenture Act of 1939, as amended, and the rules and regulations thereunder as in effect on the
date of this Indenture, except as provided in Section 10.03, and except to the extent any amendment to the Trust Indenture Act expressly provides for application of the Trust Indenture Act as in effect on another date. 

“Trading Day” means (A) except for purposes of determining amounts due upon conversion, a day on which
(i) trading in the Common Stock generally occurs on The NASDAQ Global Select Market or, if the Common Stock is not then listed on The NASDAQ Global Select Market, on the principal other U.S. national or regional securities exchange on which the
Common Stock is then listed or, if the Common Stock is not then listed on a U.S. national or regional securities exchange, on the principal other market on which the Common Stock is then traded and (ii) a Last Reported Sale Price for the Common
Stock is available on such securities exchange or market and (B) for purposes of determining amounts due upon conversion, a day on which (i) there is no Market Disruption Event and (ii) trading in the Common Stock generally occurs on
The NASDAQ Global Select Market or, if the Common Stock is not then listed on The NASDAQ Global Select Market, on the principal other U.S. national or regional securities exchange on which the Common Stock is then listed or, if the Common Stock is
not then listed on a U.S. national or regional securities exchange, on the principal other market on which the Common Stock is then listed or admitted for trading; provided that, in the case of clause (A) or (B), if the Common Stock is
not so listed or admitted for trading, “Trading Day” means a Business Day. 
 “Trading Price”
of the Notes on any date of determination means the average of the secondary market bid quotations obtained by the Bid Solicitation Agent for $5,000,000 principal amount of Notes at approximately 3:30 p.m., New York City time, on such determination
date from three independent nationally recognized securities dealers the Company selects; provided that if three such bids cannot reasonably be obtained by the Bid Solicitation Agent but two such bids are obtained, then the average of the two
bids shall be used, and if only one such bid can reasonably be obtained by the Bid Solicitation Agent, that one bid shall be used. If the Bid Solicitation Agent cannot reasonably obtain at least one bid for $5,000,000 principal amount of Notes from
a nationally recognized securities dealer, then the Trading Price per $1,000 principal 

  
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amount of Notes shall be deemed to be less than 98% of the product of the Last Reported Sale Price of Common Stock and the Conversion Rate. If the Company does not, when it is required to do so,
instruct the Bid Solicitation Agent to obtain bids, or if the Company gives such instruction to the Bid Solicitation Agent and the Bid Solicitation Agent fails to make such determination, then, in either case, the Trading Price per $1,000 principal
amount of Notes will be deemed to be less than 98% of the product of the Last Reported Sale Price of Common Stock and the Conversion Rate on each Trading Day of such failure. 
 “Trading Price Condition” has the meaning set forth in Section 4.01(c). 
 “Trustee” means the party named as such in the first paragraph of this Indenture until a successor replaces it in accordance with the provisions of this Indenture, and thereafter means
the successor. 
 “Underwriters” has the meaning set forth in the Underwriting Agreement. 

“Underwriting Agreement” means that certain Underwriting Agreement, dated as of June 22, 2011, among the Company
and Merrill Lynch, Pierce, Fenner & Smith Incorporated and Goldman, Sachs & Co. 
 “unit of Reference
Property” has the meaning set forth in Section 4.07(a). 
 “Valuation Period” has the meaning set
forth in Section 4.05(c). 
 “Vice President” when used with respect to the Company or the Trustee, means
any vice president, whether or not designated by a number or a word or words added before or after the title “vice president.” 
 Section 1.02. Trust Indenture Act Provisions. Whenever this Indenture refers to a provision of the TIA, that provision is incorporated by reference in and made a part of this Indenture. The
Indenture shall also include those provisions of the TIA required to be included herein by the provisions of the Trust Indenture Reform Act of 1990. The following TIA terms used in this Indenture have the following meanings: 

“indenture securities” means the Notes; 
 “indenture security holder” means a Holder; 
 “indenture to be
qualified” means this Indenture; and 
 “indenture trustee” or “institutional trustee” means the
Trustee; and “obligor” on the indenture securities means the Company or any other obligor on the Notes. 
 All other
terms used in this Indenture that are defined in the TIA, defined by TIA reference to another statute or defined by any SEC rule and not otherwise defined herein have the meanings assigned to them therein. 

Section 1.03. Rules of Construction. Unless the context otherwise requires: 

  
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 (a) a term has the meaning assigned to it; 

(b) an accounting term not otherwise defined has the meaning assigned to it in accordance with GAAP; 

(c) words in the singular include the plural, and words in the plural include the singular; 

(d) provisions apply to successive events and transactions; 
 (e) the term “merger” includes a statutory share exchange and the term “merged” has a correlative meaning; 
 (f) the masculine gender includes the feminine and the neuter; 
 (g) references to
agreements and other instruments include subsequent amendments thereto; and 
 (h) “herein,” “hereof” and
other words of similar import refer to this Indenture as a whole and not to any particular Article, Section or other subdivision. 
 ARTICLE 2 
 THE NOTES 

Section 2.01. Designation and Amount. The Notes shall be designated as the “2.75% Convertible Senior Notes due
2017.” The aggregate principal amount of Notes that may be authenticated and delivered under this Indenture is initially limited to $402,500,000, subject to Section 2.03 and except for Notes authenticated and delivered upon registration or
transfer of, or in exchange for, or in lieu of other Notes pursuant to Section 2.06, Section 2.07, Section 2.10, Section 3.06, Section 4.02 and Section 10.05. 

Section 2.02. Form and Dating. (a) The Notes and the Trustee’s certificate of authentication shall be substantially
in the respective forms set forth in Exhibit A, which Exhibit is incorporated in and made part of this Indenture. The Notes may have notations, legends or endorsements required by law, stock exchange rule or usage. The Company shall provide
any such notations, legends or endorsements to the Trustee in writing. Each Note shall be dated the date of its authentication. The terms and provisions contained in the Notes shall constitute, and are hereby expressly made, a part of this
Indenture, and the Company and the Trustee, by their execution and delivery of this Indenture, expressly agree to such terms and provisions and to be bound thereby. However, to the extent any provision of any Note conflicts with the express
provisions of this Indenture, the provisions of this Indenture shall govern and be controlling. 
 (b) All of the Notes shall be
issued initially in the form of one or more Global Notes, which shall be deposited on behalf of the purchasers of the Notes represented thereby with the Trustee, at its Corporate Trust Office, as custodian for the depositary, The Depository Trust
Company (“DTC”) (such depositary, or any successor thereto, being hereinafter referred to as 

  
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the “Depositary”), and registered in the name of its nominee, Cede & Co., duly executed by the Company and authenticated by the Trustee as hereinafter provided.

 Each Global Note shall represent such of the outstanding Notes as shall be specified therein and each shall provide that it
shall represent the aggregate amount of outstanding Notes from time to time endorsed thereon and that the aggregate amount of outstanding Notes represented thereby may from time to time be reduced or increased, as appropriate, to reflect exchanges,
purchases or conversions of such Notes. Any adjustment of the aggregate principal amount of a Global Note to reflect the amount of any increase or decrease in the amount of outstanding Notes represented thereby shall be made by the Trustee in
accordance with instructions given by the Holder thereof as required by Section 2.12 and shall be made on the records of the Trustee and the Depositary. 
 Members of, or participants in, the Depositary (“Agent Members”) shall have no rights under this Indenture with respect to any Global Note held on their behalf by the Depositary or under
the Global Note, and the Depositary (including, for this purpose, its nominee) may be treated by the Company, the Trustee and any agent of the Company or the Trustee as the absolute owner and Holder of such Global Note for all purposes whatsoever;
provided that any holder of a beneficial interest in a Global Note may directly enforce against the Company, without the consent, solicitation, proxy, authorization or any other action of the Depositary or any other Person, such holder’s
right to exchange such beneficial interest for a Note in certificated form in accordance with the provisions of this Indenture. Notwithstanding the foregoing, nothing herein shall (1) prevent the Company, the Trustee or any agent of the Company
or the Trustee from giving effect to any written certification, proxy or other authorization furnished by the Depositary or (2) impair, as between the Depositary and its Agent Members, the operation of customary practices governing the exercise
of the rights of a Holder of any Note. 
 (c) The Company shall execute and the Trustee shall, in accordance with this
Section 2.02(c), authenticate and deliver initially one or more Global Notes that (1) shall be registered in the name of the Depositary, (2) shall be delivered by the Trustee to the Depositary or pursuant to the Depositary’s
instructions and (3) shall bear a legend substantially to the following effect: 
 “UNLESS THIS CERTIFICATE IS
PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY TO THE COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER
NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (AND ANY PAYMENT HEREON IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY), ANY
TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL SINCE THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE
HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF A DEPOSITARY OR A NOMINEE 

  
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THEREOF. THIS SECURITY IS EXCHANGEABLE FOR SECURITIES REGISTERED IN THE NAME OF A PERSON OTHER THAN THE DEPOSITARY OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE AND
UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR
ANOTHER NOMINEE OF THE DEPOSITARY OR BY THE DEPOSITARY OR ANY SUCH NOMINEE TO A SUCCESSOR DEPOSITARY OR A NOMINEE OF SUCH SUCCESSOR DEPOSITARY.” 
 Section 2.03. Execution and Authentication; Payments of Interest and Defaulted Amounts. (a) The Notes shall be issuable only in registered form without coupons and only in denominations
of $1,000 principal amount and any integral multiple thereof. An Officer shall sign the Notes for the Company by manual or facsimile signature attested by the manual or facsimile signature of the Secretary or an Assistant Secretary of the Company.
Typographic and other minor errors or defects in any such facsimile signature shall not affect the validity or enforceability of any Note which has been authenticated and delivered by the Trustee. If an Officer whose signature is on a Note no longer
holds that office at the time the Trustee authenticates the Note, the Note shall be valid nevertheless. A Note shall not be valid until an authorized signatory of the Trustee manually signs the certificate of authentication on the Note. The
signature shall be conclusive evidence that the Note has been authenticated under this Indenture. 
 (b) The Trustee shall
authenticate and make available for delivery Notes for original issue in the aggregate principal amount of up to $402,500,000 upon receipt of a Company Order. The Company Order shall specify the amount of Notes to be authenticated, shall provide
that all such Notes will be represented by a Global Note and the date on which each original issue of Notes is to be authenticated. The Company at any time or from time to time may, without the consent of the Holders, issue additional Notes in an
unlimited aggregate principal amount under this Indenture with the same terms as the Notes initially issued hereunder; provided that if the additional Notes are not fungible with the Notes initially issued hereunder for U.S. federal income
tax purposes, the additional Notes shall have a separate CUSIP number. Such additional Notes shall, together with the Notes initially issued hereunder, constitute a single series of Notes under this Indenture, including without limitation in
determining the necessary Holders who may take the actions or consent to the taking of actions as specified in this Indenture. 

(c) Accrued interest on the Notes shall be computed on the basis of a 360-day year composed of twelve 30-day months. The Person in whose
name any Note (or its predecessor) is registered on register of the Primary Registrar at the close of business on any Regular Record Date with respect to any Interest Payment Date shall be entitled to receive the interest payable on such Interest
Payment Date. Interest shall be payable at the office or agency of the Company maintained by the Company for such purposes, which shall initially be the Corporate Trust Office. The Company shall pay interest (i) on any Certificated Notes
(A) to Holders having an aggregate principal amount of $5.0 million or less, by check mailed to the Holders of these Notes at their address as it appears in the register of the Primary Registrar and (B) to Holders having an

  
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aggregate principal amount of more than $5.0 million, either by check mailed to the Holders of these Notes or upon application by a Holder to the Primary Registrar not later than the relevant
Regular Record Date, by wire transfer in immediately available funds to that Holder’s account within the United States, which application shall remain in effect until the Holder notifies, in writing, the Primary Registrar to the contrary or
(ii) through the Paying Agent, on any Global Note by wire transfer of immediately available funds to the account of the Depositary or its nominee. 
 (d) Any Defaulted Amounts shall forthwith cease to be payable to the Holder on the relevant payment date by virtue of its having been such Holder but shall accrue interest per annum at the rate borne by
the Notes, subject to the enforceability thereof under applicable law, from, and including, such relevant payment date to, but excluding, the date on which such Defaulted Amounts shall have been paid by the Company, at its election in each case, as
provided in subsection (i) or (ii) below: 
 (i) The Company may elect to make payment of any Defaulted
Amounts to the Persons in whose names the Notes (or their respective predecessor Notes) are registered at the close of business on a special record date for the payment of such Defaulted Amounts, which shall be fixed in the following manner. The
Company shall notify the Trustee in writing of the amount of the Defaulted Amounts proposed to be paid on each Note and the date of the proposed payment (which shall be not less than 25 days after the receipt by the Trustee of such notice, unless
the Trustee shall consent to an earlier date), and at the same time the Company shall deposit with the Trustee an amount of money equal to the aggregate amount to be paid in respect of such Defaulted Amounts or shall make arrangements satisfactory
to the Trustee for such deposit on or prior to the date of the proposed payment, such money when deposited to be held in trust for the benefit of the Persons entitled to such Defaulted Amounts as in this clause provided. Thereupon the Company shall
fix a special record date for the payment of such Defaulted Amounts which shall be not more than 15 days and not less than 10 days prior to the date of the proposed payment, and not less than 10 days after the receipt by the Trustee of the notice of
the proposed payment. The Company shall promptly notify the Trustee of such special record date and the Trustee, in the name and at the expense of the Company, shall cause notice of the proposed payment of such Defaulted Amounts and the special
record date therefor to be mailed, first-class postage prepaid, to each Holder at its address as it appears in the register of the Primary Registrar, not less than 10 days prior to such special record date. Notice of the proposed payment of such
Defaulted Amounts and the special record date therefor having been so mailed, such Defaulted Amounts shall be paid to the Persons in whose names the Notes (or their respective predecessor Notes) are registered at the close of business on such
special record date and shall no longer be payable pursuant to the following subsection (ii) of this Section 2.03(d). 
 (ii) The Company may make payment of any Defaulted Amounts in any other lawful manner not inconsistent with the requirements of any securities exchange or automated quotation system on which the Notes may
be listed or designated for issuance, and upon such notice as may be required by such exchange or automated quotation system, if, after notice given by the Company to the Trustee of the proposed payment

  
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pursuant to this clause, such manner of payment shall be deemed practicable by the Trustee. 
 Section 2.04. Registrar, Paying Agent and Conversion Agent. The Company shall maintain one or more offices or agencies where Notes may be presented for registration of transfer or for exchange
(each, a “Registrar”), one or more offices or agencies where Notes may be presented for payment (each, a “Paying Agent”), one or more offices or agencies where Notes may be presented for conversion (each, a
“Conversion Agent”) and one or more offices or agencies where notices and demands to or upon the Company in respect of the Notes and this Indenture may be served. The Company will at all times maintain a Paying Agent, Conversion
Agent, Registrar and an office or agency where notices and demands to or upon the Company in respect of the Notes and this Indenture may be served in the Borough of Manhattan, The City of New York. One of the Registrars (the “Primary
Registrar”) shall keep a register of the Notes and of their registration of transfer and exchange. The Company shall give prompt written notice to the Trustee of the location, and any change in the location, of such office or agency.

 The Company shall enter into an appropriate agency agreement with any Agent not a party to this Indenture. The agreement
shall implement the provisions of this Indenture that relate to such Agent. The Company shall give prompt written notice to the Trustee of the name and address of any Agent not a party to this Indenture. If the Company fails to maintain a Registrar,
Paying Agent, Conversion Agent or agent for service of notices and demands in any place required by this Indenture, or fails to give the foregoing notice, the Trustee shall act as such. The Company or any Affiliate of the Company may act as Paying
Agent (except for the purposes of Article 9). 
 The Company hereby initially designates the Trustee as Paying Agent, Primary
Registrar, Notes Custodian and Conversion Agent and each of the Corporate Trust Office of the Trustee and the office or agency of the Trustee in the Borough of Manhattan, The City of New York, as an office or agency of the Company for each of the
aforesaid purposes. The Company may, however, change the Paying Agent, Registrar or Primary Registrar without prior notice to the Holders but shall promptly notify the Holders through the Trustee following any such change, and may act as Paying
Agent, Registrar or Primary Registrar. 
 Section 2.05. Paying Agent to Hold Money in Trust. Prior to 5:00 p.m., New
York City time, on each due date of the principal of or interest on any Notes (including the Fundamental Change Repurchase Price, if any), the Company shall deposit with a Paying Agent a sum sufficient to pay such principal or interest (including
the Fundamental Change Repurchase Price, if any) so becoming due. A Paying Agent shall hold in trust for the benefit of the Holders or the Trustee all money held by the Paying Agent for the payment of principal of or interest on the Notes (including
the Fundamental Change Repurchase Price, if any), and shall notify the Trustee of any default by the Company (or any other obligor on the Notes) in making any such payment. The Paying Agent shall apply the deposited money in accordance with this
Indenture and the Notes to the payment of the principal of, and interest on, the Notes (including the Fundamental Change Repurchase Price, if any); provided that such money need not be segregated from other funds except to the extent required
by law. If the Company or an Affiliate of the Company acts as Paying Agent, it shall, before 5:00 p.m., New York City time, on each due date of the principal of or interest on any Notes (including the Fundamental Change Repurchase Price, if

  
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any), segregate the money and hold it as a separate trust fund for the benefit of the Holders. The Company at any time may require a Paying Agent to pay all money held by it to the Trustee, and
the Trustee may at any time during the continuance of any default, upon written request to a Paying Agent, require such Paying Agent to pay forthwith to the Trustee all sums so held in trust by such Paying Agent. Upon doing so, the Paying Agent
(other than the Company) shall have no further liability for the money. 
 Section 2.06. Transfer and Exchange.
(a) Subject to compliance with any applicable additional requirements contained in Section 2.12, when a Note is presented to a Registrar with a request to register a transfer thereof or to exchange such Note for an equal principal
amount of Notes of other authorized denominations, the Registrar shall register the transfer or make the exchange as requested; provided, however, that every Note presented or surrendered for registration of transfer or exchange shall
be duly endorsed or accompanied by an assignment form in form satisfactory to the Registrar duly executed by the Holder thereof or its attorney duly authorized in writing. To permit registration of transfers and exchanges, upon surrender of any Note
for registration of transfer or exchange at an office or agency maintained pursuant to Section 2.04, the Company shall execute and the Trustee shall authenticate Notes of a like aggregate principal amount at the Registrar’s request. No
service charge may be imposed by the Company, the Trustee or any Registrar for any transfer or exchange of a Note, except that the Company, the Trustee or any Registrar may require a Holder to pay a sum sufficient to cover any transfer tax or other
similar governmental charge that may be imposed in relation thereto; provided that this sentence shall not apply to any exchange pursuant to Section 2.07, Section 2.10, Section 3.06, Section 4.02(d) or Section 10.05.

 Neither the Company, any Registrar nor the Trustee shall be required to exchange or register a transfer of any Notes or
portions thereof in respect of which (x) a Repurchase Notice pursuant to Section 3.02(c) has been delivered and not withdrawn by the Holder thereof (except, in the case of the purchase of a Note in part, the portion thereof not to be
purchased) or (y) a Conversion Notice has been delivered pursuant to Section 4.02(b) (except, if a portion of the principal amount of a Note has been surrendered for conversion, the portion thereof not being converted). 

All Notes issued upon any transfer or exchange of Notes shall be valid obligations of the Company, evidencing the same debt and entitled
to the same benefits under this Indenture, as the Notes surrendered upon such transfer or exchange. 
 (b) Any Registrar
appointed pursuant to Section 2.04 shall provide to the Trustee such information as the Trustee may reasonably require in connection with the delivery by such Registrar of Notes upon transfer or exchange of Notes. 

(c) The Trustee shall have no obligation or duty to monitor, determine or inquire as to compliance with any restrictions on transfer
imposed under this Indenture or under applicable law with respect to any transfer of any interest in any Note (including any transfers between or among Agent Members or other beneficial owners of interests in any Global Note) other than to require
delivery of such certificates and other documentation or evidence as are expressly required by, and to do so if and when expressly required by the terms of, this Indenture, and to 

  
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examine the same to determine substantial compliance as to form with the express requirements hereof. 
 Neither the Trustee nor any Agent shall have any responsibility for any actions taken or not taken by the Depositary. 
 Section 2.07. Replacement Notes. If any mutilated Note is surrendered to the Company, a Registrar or the Trustee, or the Trustee receives evidence to its satisfaction of the destruction, loss
or theft of any Note, and there is delivered to the Company, the applicable Registrar and the Trustee such security or indemnity as will be required by them to save each of them harmless, then, in the absence of notice to the Company, such Registrar
or the Trustee that such Note has been acquired by a protected purchaser, the Company shall execute, and upon its written request the Trustee shall authenticate and deliver, in exchange for any such mutilated Note or in lieu of any such destroyed,
lost or stolen Note, a new Note of like tenor and principal amount, bearing a number not contemporaneously outstanding. 
 In
case the principal amount of any such mutilated, destroyed, lost or stolen Note has become due and payable, the Company in its discretion may, instead of issuing a new Note, pay all amounts due on such Note. 

Upon the issuance of any new Notes under this Section 2.07, the Company may require the payment of a sum sufficient to cover any tax
or other governmental charge that may be imposed in relation thereto and any other reasonable expenses (including the reasonable fees and expenses of the Trustee or the Registrar) in connection therewith. 

Every new Note issued pursuant to this Section 2.07 in lieu of any mutilated, destroyed, lost or stolen Note shall constitute an
original additional contractual obligation of the Company, whether or not the mutilated, destroyed, lost or stolen Note shall be at any time enforceable by anyone, and shall be entitled to all benefits of this Indenture equally and proportionately
with any and all other Notes duly issued hereunder. 
 The provisions of this Section 2.07 are (to the extent lawful)
exclusive and shall preclude (to the extent lawful) all other rights and remedies with respect to the replacement or payment of mutilated, destroyed, lost or stolen Notes. 
 Section 2.08. Outstanding Notes. Notes outstanding at any time are all Notes authenticated by the Trustee, except for those canceled by it, those converted pursuant to Article 4, those
delivered to it for cancellation or surrendered for transfer or exchange, those described in this Section 2.08 as not outstanding and those repurchased by the Company pursuant to the second paragraph of Section 2.11. 

If a Note is replaced pursuant to Section 2.07, it ceases to be outstanding unless the Trustee receives proof satisfactory to it
that the replaced Note is held by a protected purchaser. 
 If a Paying Agent (other than the Company or an Affiliate of the
Company) holds on the Maturity Date money sufficient to pay the principal of and accrued interest on Notes (or portions thereof) payable on that date, then on and after such Maturity Date such Notes (or portions

  
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thereof, as the case may be) shall cease to be outstanding and interest on them shall cease to accrue, subject to Section 9.04. 

Section 2.09. Treasury Notes. In determining whether the Holders of the required principal amount of Notes have concurred in
any notice, direction, waiver or consent, Notes owned by the Company or any other obligor on the Notes or by any Affiliate of the Company or of such other obligor shall be disregarded, except that, for purposes of determining whether the Trustee
shall be protected in relying on any such notice, direction, waiver or consent, only Notes that a Responsible Officer of the Trustee actually knows are so owned shall be so disregarded. Notes so owned that have been pledged in good faith shall not
be disregarded if the pledgee establishes to the satisfaction of the Trustee the pledgee’s right so to act with respect to the Notes and that the pledgee is not the Company or any other obligor on the Notes or any Affiliate of the Company or of
such other obligor. 
 Section 2.10. Temporary Notes. Until definitive Notes are ready for delivery, the Company may
prepare and execute, and, upon receipt of a Company Order, the Trustee shall authenticate and deliver, temporary Notes. Temporary Notes shall be substantially in the form of Certificated Notes but may have variations that the Company considers
appropriate for temporary Notes and as shall be reasonably acceptable to the Trustee. Without unreasonable delay, the Company shall prepare and the Trustee, upon receipt of a Company Order, shall authenticate and deliver definitive Notes in exchange
for temporary Notes. Holders of temporary Notes shall be entitled to all the benefits of this Indenture equally and proportionately with any and all other Notes duly issued hereunder. 

Section 2.11. Cancellation; Repurchase. The Company shall cause all Notes surrendered for the purpose of payment, repurchase
(including as described in the following paragraph), registration of transfer or exchange or conversion, if surrendered to any Person other than the Trustee (including any of the Company’s agents, Subsidiaries or Affiliates), to be delivered to
the Trustee for cancellation. The Registrar, the Paying Agent and the Conversion Agent shall forward to the Trustee or its agent any Notes surrendered to them for registration of transfer, exchange, payment or conversion. The Trustee and no one else
shall promptly cancel, in accordance with its standard procedures, all Notes surrendered for the purpose of payment, repurchase, registration of transfer, exchange, conversion or cancellation and shall dispose of canceled Notes (subject to the
record retention requirements of the Exchange Act), in accordance with its standard procedures, and no Notes shall be authenticated in exchange thereof except as expressly permitted by any of the provisions of this Indenture. The Company may not
hold or resell such Notes or issue new Notes to replace Notes that it has purchased or otherwise acquired or that have been delivered to the Trustee for cancellation (other than issuing new Notes as expressly permitted by this Indenture in respect
of Notes that have been surrendered to the Company for the purpose of registration of transfer or exchange or, in the case of a partial conversion or repurchase upon a Fundamental Change, in respect of the portion thereof that is not so converted or
repurchased). 
 The Company may, to the extent permitted by law, and directly or indirectly (regardless of whether such Notes
are surrendered to the Company), repurchase Notes in the open market or otherwise, whether by the Company or its Subsidiaries or through a private or public tender or exchange offer or through counterparties to private agreements, including by
cash-settled swaps 

  
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or other derivatives. The Company shall cause any Notes so repurchased (other than Notes repurchased pursuant to cash-settled swaps or other cash-settled derivatives) to be surrendered to the
Trustee for cancellation in accordance with this Section 2.11. 
 Section 2.12. Additional Transfer and Exchange
Requirements. (a) A Global Note may not be transferred, in whole or in part, to any Person other than the Depositary or a nominee or successor thereof, and no such transfer to any such other Person may be registered; provided that
the foregoing shall not prohibit any transfer of a Note that is issued in exchange for a Global Note but is not itself a Global Note. No transfer of a Note to any Person shall be effective under this Indenture or the Notes unless and until such Note
has been registered in the name of such Person. Notwithstanding any other provisions of this Indenture or the Notes, transfers of a Global Note, in whole or in part, shall be made only in accordance with this Section 2.12. 

(b) The provisions of subsections (i), (ii), (iii), (iv) and (v) below shall apply only to Global Notes: 

(i) Notwithstanding any other provisions of this Indenture or the Notes, a Global Note shall not be exchanged in whole or
in part for a Note registered in the name of any Person other than the Depositary or one or more nominees thereof; provided that a Global Note may be exchanged for Certificated Notes in the event that (A) the Depositary has notified the
Company that it is unwilling or unable to continue as Depositary for such Global Note or the Depositary has ceased to be a “clearing agency” registered under the Exchange Act, and, in either case, a successor Depositary is not appointed by
the Company within 90 days or (B) an Event of Default has occurred and is continuing and a beneficial owner requests that its Notes be exchanged for Certificated Notes. Any Global Note exchanged pursuant to clause (A) above shall be so
exchanged in whole and not in part and the Certificated Notes so issued shall be registered in the names of any Person designated by the Depositary, and any Global Note exchanged pursuant to clause (B) above may be exchanged in whole or from
time to time in part and the Certificated Notes so issued shall be registered in the names of the beneficial owner or owners making such request and the Certificated Notes shall have a principal amount corresponding to their beneficial interests in
the Global Note. Any Note issued in exchange for a Global Note or any portion thereof shall be a Global Note; provided, further, that any such Note so issued that is registered in the name of a Person other than the Depositary or a nominee
thereof shall not be a Global Note. 
 (ii) Notes issued in exchange for a Global Note or any portion thereof
pursuant to the first proviso in clause (i) above shall be issued in fully-registered book-entry form, without interest coupons, shall have an aggregate principal amount equal to that of such Global Note or portion thereof to be so exchanged,
and, in the case of clause (A) in such proviso, shall be registered in such names and be in such authorized denominations as the Depositary shall designate and shall bear any applicable legend provided for herein. Any Global Note to be
exchanged in whole shall be surrendered by the Depositary to the Trustee, as Registrar. With regard to any Global Note to be exchanged in part, pursuant to the first proviso in clause (i) above, either such Global Note shall be so surrendered
for exchange or, if the Trustee is acting as Notes Custodian for the Depositary or its nominee with respect to such Global Note, the principal amount 

  
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thereof shall be reduced, by an amount equal to the portion thereof to be so exchanged, by means of an appropriate adjustment made on the records of the Trustee. Upon any such surrender or
adjustment, in the case of clause (i)(A) above, the Trustee shall authenticate and deliver the Note issuable on such exchange to or upon the order of the Depositary or an authorized representative thereof; provided, however, that any
Global Note surrendered for exchange shall be duly endorsed or accompanied by a written instrument of transfer in accordance with the proviso to the first paragraph of Section 2.06(a). 

(iii) Subject to the provisions of subsection (v) below, the registered Holder may grant proxies and otherwise
authorize any Person, including Agent Members and Persons that may hold interests through Agent Members, to take any action which a Holder is entitled to take under this Indenture or the Notes. 

(iv) In the event of the occurrence of any of the events specified in subsection (i) above, the Company will promptly
make available to the Trustee a reasonable supply of Certificated Notes in definitive, fully registered form, without interest coupons. 
 (v) Neither Agent Members nor any other Persons on whose behalf Agent Members may act shall have any rights under this Indenture with respect to any Global Note registered in the name of the Depositary or
any nominee thereof, or under any such Global Note, and the Depositary or such nominee, as the case may be, may be treated by the Company, the Trustee and any agent of the Company or the Trustee as the absolute owner and holder of such Global Note
for all purposes whatsoever, subject to the last sentence of Section 12.03. Notwithstanding the foregoing, nothing herein shall prevent the Company, the Trustee or any agent of the Company or the Trustee from giving effect to any written
certification, proxy or other authorization furnished by the Depositary or such nominee, as the case may be, or impair, as between the Depositary, its Agent Members and any other Person on whose behalf an Agent Member may act, the operation of
customary practices of such Persons governing the exercise of the rights of a holder of any Note. 
 (c) In the event that
Certificated Notes are issued in exchange for beneficial interests in Global Notes and, thereafter, the events or conditions specified in Section 2.12(b)(i) that required such exchange shall cease to exist, the Company shall deliver notice to
the Trustee and to the Holders stating that Holders may exchange Certificated Notes for interests in Global Notes by complying with the procedures set forth in this Indenture and briefly describing such procedures and the events or circumstances
requiring that such notice be given. Thereafter, if Certificated Notes are presented by a Holder to a Registrar with a request: 
 (i) to register the transfer of such Certificated Notes to a Person who will take delivery thereof in the form of a beneficial interest in a Global Note; or 

(ii) to exchange such Certificated Notes for an equal principal amount of beneficial interests in a Global Note, which
beneficial interests will be owned by the Holder transferring such Certificated Notes, 

  
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 the Registrar shall register the transfer or make the exchange as requested by canceling such Certificated
Notes and causing, or directing the Notes Custodian to cause, the aggregate principal amount of the applicable Global Note to be increased accordingly and, if no such Global Note is then outstanding, the Company shall issue and the Trustee, upon
receipt of a Company Order, shall authenticate and deliver a new Global Note; provided, however, that the Certificated Notes presented or surrendered for registration of transfer or exchange shall be duly endorsed or accompanied by a
written instrument of transfer in accordance with the proviso to the first paragraph of Section 2.06(a). 

Section 2.13. CUSIP Numbers. The Company in issuing the Notes may use one or more “CUSIP” numbers (if then
generally in use), and, if so, the Trustee shall use “CUSIP” numbers in notices as a convenience to Holders; provided that any such notice may state that no representation is made as to the correctness of such numbers either as
printed on the Notes or as contained in any notice and that reliance may be placed only on the other identification numbers printed on the Notes, and any such notice or related action by the Company contemplated thereby shall not be affected by any
defect in or omission of such numbers. The Company will promptly notify the Trustee of any change in the “CUSIP” numbers. 
 ARTICLE 3 
 NO REDEMPTION; REPURCHASE
UPON A FUNDAMENTAL CHANGE 
 Section 3.01. No Optional
Redemption. The Company shall not have the option to redeem the Notes prior to the Maturity Date. No sinking fund is provided for the Notes. 
 Section 3.02. Repurchase At Option of The Holder Upon A Fundamental Change. (a) Subject to the satisfaction of the requirements of this Article 3, if a Fundamental Change occurs at any
time, each Holder shall have the right, at its option, to require the Company to repurchase all of its Notes, or any portion of the principal amount thereof that is equal to $1,000 or an integral multiple of $1,000, on a date (the
“Fundamental Change Repurchase Date”) of the Company’s choosing that is not less than 15 nor more than 35 days after the date of the Fundamental Change Repurchase Right Notice. The Fundamental Change repurchase price the
Company is required to pay (the “Fundamental Change Repurchase Price”) is equal to 100% of the principal amount of the Notes to be repurchased plus accrued and unpaid interest, if any, to, but not including, the Fundamental Change
Repurchase Date; provided that if the Fundamental Change Repurchase Date falls after a Regular Record Date and on or prior to the Interest Payment Date to which it relates, the Company shall instead pay the full amount of accrued and unpaid
interest to the Holder of record at the close of business on such Regular Record Date, and the Fundamental Change Repurchase Price shall be equal to 100% of the principal amount of the Notes to be repurchased. Any Notes so repurchased by the Company
shall be paid for in cash. 
 (b) In addition to any notice obligation the Company may have under Section 4.01(e) or
Section 4.04(a), after the occurrence of a Fundamental Change, but on or before the 15th day following such occurrence, the Company shall notify all Holders of the Notes and the Trustee and the Paying Agent of the occurrence of the Fundamental
Change and of the resulting 

  
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repurchase right, if any (the “Fundamental Change Repurchase Right Notice”). Such Fundamental Change Repurchase Right Notice shall state: 

(i) the events causing the Fundamental Change; 

(ii) the date of the Fundamental Change; 

(iii) the last date on which a Holder may exercise the repurchase right, if applicable; 

(iv) the Fundamental Change Repurchase Price, if applicable; 

(v) the Fundamental Change Repurchase Date, if applicable; 

(vi) the name and address of the Paying Agent and the Conversion Agent, if applicable; 

(vii) the applicable Conversion Rate and any adjustments to the applicable Conversion Rate; 

(viii) that the Notes with respect to which a Repurchase Notice has been delivered by a Holder may be converted only if
the Holder withdraws the Repurchase Notice as described in Section 3.02(d); and 
 (ix) the procedures that
Holders must follow to require the Company to repurchase their Notes, if applicable. 
 Simultaneously with providing such
Fundamental Change Repurchase Right Notice, the Company shall publish such information on the Company’s website or through such other public medium as the Company may use at that time. 

(c) To exercise the right to cause the Company to repurchase its Notes pursuant to this Article 3, a Holder must deliver, on or before
the Business Day prior to the Fundamental Change Repurchase Date, the Notes to be repurchased. If the Notes are Global Notes, such delivery (and the related Repurchase Notice) must comply with all Applicable Procedures. If the Notes are Certificated
Notes, such Notes must be duly endorsed for transfer, and must be delivered by the Holder together with a written Repurchase Notice exercising such Holder’s right to require the Company to repurchase its Notes or a portion thereof,
substantially in the form included in Exhibit A hereto, duly completed, to the Paying Agent. The “Repurchase Notice” must state: 
 (i) if the Notes are Certificated Notes, the certificate numbers of the Notes to be delivered for repurchase; 
 (ii) the portion of the principal amount of the Notes to be repurchased, which must be equal to $1,000 or an integral multiple thereof; and 

(iii) that the Notes are to be repurchased by the Company pursuant to the applicable provisions of the Notes and this
Indenture. 

  
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 (d) A Holder may withdraw any Repurchase Notice delivered pursuant to Section 3.02(c),
in whole or in part, by a written notice of withdrawal delivered to the Paying Agent prior to the close of business on the Business Day immediately preceding the relevant Fundamental Change Repurchase Date. The notice of withdrawal shall state:

 (i) the principal amount of the Notes for which the Repurchase Notice has been withdrawn; 

(ii) if the Notes are Certificated Notes, the certificate numbers of the withdrawn Notes; and 

(iii) the principal amount, if any, which remains subject to the Repurchase Notice; 

provided that if the Notes are Global Notes, such withdrawal notice must comply with Applicable Procedures. 

(e) Holders who have surrendered their Notes for repurchase upon a Fundamental Change in accordance with Section 3.02(c) shall
receive payment of the Fundamental Change Repurchase Price promptly following the later of (x) the Fundamental Change Repurchase Date or (y) the time of book-entry transfer or the delivery of the Notes, as applicable. Subject to
Section 9.04 and the right of the Holder of record as of the close of business on the relevant Regular Record Date to receive the relevant interest payment on the related Interest Payment Date where the Fundamental Change Repurchase Date falls
between such Regular Record Date and such related Interest Payment Date, if the Paying Agent or the Trustee holds money sufficient to pay the Fundamental Change Repurchase Price for the Notes that have been surrendered for repurchase, pursuant to
Section 3.02(c), on the Business Day following the Fundamental Change Repurchase Date, then: 
 (i) such
Notes shall cease to be outstanding and interest shall cease to accrue whether or not book-entry transfer of such Notes is made or whether or not such Notes are delivered to the Paying Agent; and 

(ii) all other rights of the Holders of such Notes shall terminate other than the right to receive the Fundamental Change
Repurchase Price including any accrued and unpaid interest, if any, upon delivery or transfer of the Notes. 

Section 3.03. Compliance With Securities Laws Upon Purchase of Notes. In connection with any offer to purchase the Notes upon
a Fundamental Change under Section 3.02, the Company shall (a) comply with the provisions of Rule 13e-4 and Rule 14e-l and any other tender offer rules under the Exchange Act that may then be applicable and (b) otherwise comply with
all applicable federal and state securities laws. 
 Section 3.04. No Repurchase Upon Acceleration. No Notes may be
repurchased on any date at the option of Holders upon a Fundamental Change if the principal amount of the Notes has been accelerated, and such acceleration has not been rescinded, on or prior to such date. The Paying Agent will promptly return to
the respective Holders thereof any Certificated Notes held by it following the acceleration of the Notes, and any instructions for book-entry transfer of the 

  
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Notes in compliance with the Applicable Procedures shall be deemed to have been cancelled, and, upon such return or cancellation, as the case may be, the Repurchase Notice with respect thereto
shall be deemed to have been withdrawn. 
 Section 3.05. Repayment to the Company. To the extent that the aggregate
amount of cash deposited by the Company pursuant to Section 3.02 exceeds the aggregate Fundamental Change Repurchase Price of the Notes or portions thereof that the Company is obligated to purchase, then promptly after the payment of the
Fundamental Change Repurchase Price, the Trustee or a Paying Agent, as the case may be, shall return any such excess cash to the Company. 
 Section 3.06. Partial Repurchase. Upon surrender of a Note that is to be repurchased in part pursuant to Section 3.02, the Company shall execute and the Trustee shall authenticate and
deliver to the Holder a new Note in an authorized denomination equal in principal amount to the unrepurchased portion of the Note surrendered. 
 ARTICLE 4 
 CONVERSION 

Section 4.01. Conversion Rights. (a) Subject to and upon compliance with the provisions of this Article 4, each Holder
of a Note shall have the right, at such Holder’s option, to convert all or any portion (if the portion to be converted is $1,000 principal amount or an integral multiple thereof) of such Note (i) subject to satisfaction of one or more of
the conditions described in subsections (b) through (e) of this Section 4.01, at any time prior to the close of business on the Business Day immediately preceding January 1, 2017 under the circumstances and during the periods set
forth in subsections (b) through (e) of this Section 4.01, and (ii) irrespective of the conditions set forth in subsections (b) through (e) of this Section 4.01, on or after January 1, 2017 and prior to the
close of business on the second Scheduled Trading Day immediately preceding the Maturity Date, in each case, at an initial conversion rate of 23.7344 shares of Common Stock (subject to adjustment as provided in Section 4.04 and
Section 4.05, the “Conversion Rate”) per $1,000 principal amount of Notes (subject to the settlement provisions of Section 4.02, the “Conversion Obligation”). 

(b) Prior to the close of business on the Business Day immediately preceding January 1, 2017, a Holder may surrender all or a
portion of its Notes for conversion during any calendar quarter commencing after the calendar quarter ending on September 30, 2011 (and only during such calendar quarter), if the Last Reported Sale Price of Common Stock for at least 20 Trading
Days (whether or not consecutive) during the period of 30 consecutive Trading Days ending on the last Trading Day of the immediately preceding calendar quarter is greater than or equal to 130% of the Conversion Price on each applicable Trading Day.
The Conversion Agent, on behalf of the Company, shall determine at the beginning of each calendar quarter commencing after September 30, 2011 if the Notes have become convertible pursuant to this Section 4.01(b), in which case the
Conversion Agent shall so notify the Company and the Holders through the 

  
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Trustee within five Business Days of the Notes becoming convertible pursuant to this Section 4.01(b). 
 (c) Prior to the close of business on the Business Day immediately preceding January 1, 2017, a Holder of the Notes may surrender its Notes for conversion during the five Business Day period after
any five consecutive Trading Day period (the “Measurement Period”) in which the Trading Price per $1,000 principal amount of the Notes, as determined following a request by a Holder of the Notes in accordance with the procedures
described below and in the definition of “Trading Price” in Section 1.01, for each Trading Day of the Measurement Period was less than 98% of the product of the Last Reported Sale Price of Common Stock and the Conversion Rate on such
Trading Day (the “Trading Price Condition”). The Bid Solicitation Agent shall have no obligation to determine the Trading Price per $1,000 principal amount of the Notes unless the Company has requested such determination; and the
Company shall have no obligation to make such request unless a Holder provides the Company with reasonable evidence that the Trading Price per $1,000 principal amount of the Notes would be less than 98% of the product of the Last Reported Sale Price
of Common Stock and the Conversion Rate. At such time, the Company shall instruct the Bid Solicitation Agent to determine the Trading Price per $1,000 principal amount of Notes beginning on the next Trading Day and on each successive Trading Day
until the Trading Price per $1,000 principal amount of Notes is greater than or equal to 98% of the product of the Last Reported Sale Price of Common Stock and the Conversion Rate. If the Trading Price Condition has been met, the Company shall so
notify the Holders, the Trustee and the Conversion Agent (if other than the Trustee) within one Business Day. If, at any time after the Trading Price Condition has been met, the Trading Price per $1,000 principal amount of Notes is greater than or
equal to 98% of the product of the Last Reported Sale Price of Common Stock and the Conversion Rate for such date, the Company shall notify the Holders, the Trustee and the Conversion Agent (if other than the Trustee) within one Business Day.

 (d) If, prior to the close of business on the Business Day immediately preceding January 1, 2017, the Company elects to:

 (i) issue to all or substantially all holders of Common Stock any rights, options or warrants entitling them,
for a period of not more than 45 calendar days after the announcement date of such issuance, to subscribe for or purchase shares of Common Stock at a price per share that is less than the average of the Last Reported Sale Prices of the Common Stock
for the 10 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the date of announcement of such issuance; or 
 (ii) distribute to all or substantially all holders of Common Stock the Company’s assets, debt securities or rights to purchase the Company’s securities, which distribution has a per share
value, as reasonably determined by the Board of Directors, exceeding 10% of the Last Reported Sale Price of the Common Stock on the Trading Day preceding the date of announcement of such distribution, 

then, in either case, the Company shall notify the Holders of the Notes at least 55 Scheduled Trading Days prior to the Ex-Dividend Date for such
issuance or distribution. Once the Company has given such notice, Holders may surrender their Notes for conversion at any time 

  
 -25-

 
until the earlier of the close of business on the Business Day immediately preceding the Ex-Dividend Date for such issuance or distribution and the Company’s announcement that such issuance
or distribution will not take place, even if the Notes are not otherwise convertible at such time. 
 (e) If a transaction or
event that constitutes a Fundamental Change or a Make-Whole Fundamental Change occurs prior to the close of business on the Business Day immediately preceding January 1, 2017, regardless of whether a Holder of the Notes has the right to require
the Company to repurchase the Notes pursuant to Section 3.02, or if the Company is a party to a consolidation, merger, binding share exchange, or transfer or lease of all or substantially all of the Company’s assets, pursuant to which the
Common Stock would be converted into cash, securities or other assets, the Notes may be surrendered for conversion at any time from or after the date that is 55 Scheduled Trading Days prior to the anticipated effective date of the transaction (or,
if later, the Business Day after the Company gives notice of such transaction) until 35 Trading Days after the actual effective date of such transaction or, if such transaction also constitutes a Fundamental Change, until the related Fundamental
Change Repurchase Date. The Company shall notify the Holders, the Trustee and the Conversion Agent (if other than the Trustee) (i) as promptly as practicable following the date the Company or a third party publicly announces such anticipated
transaction but in no event less than 55 Scheduled Trading Days prior to the anticipated effective date of such transaction; or (ii) if the Company does not have knowledge of such transaction at least 55 Scheduled Trading Days prior to the
anticipated effective date of such transaction, then within one Business Day of the date upon which the Company receives notice, or otherwise becomes aware, of such transaction, but in no event later than the actual effective date of such
transaction. 
 Section 4.02. Settlement Upon Conversion; Conversion Procedures. (a) If the Company has not
received the Stockholder Approvals prior to the relevant Settlement Method Election Date, the Company must settle any conversion of a Note by Cash Settlement. If the Company has received the Stockholder Approvals prior to the relevant Settlement
Method Election Date, upon conversion of a Note, the Company shall, subject to this Section 4.02, Section 4.04(b) and Section 4.07, pay or deliver, as the case may be, to the converting Holder, in respect of each $1,000 principal
amount of such Note being converted cash (“Cash Settlement”), shares of Common Stock, together with cash, if applicable, in lieu of any fractional share of Common Stock in accordance with subsection (i) of this
Section 4.02 (“Physical Settlement”) or a combination of cash and shares of Common Stock (“Combination Settlement”), at its election, as set forth in this Section 4.02. 

(i) All conversions occurring on or after January 1, 2017 shall be settled using the same Settlement Method. Prior to
January 1, 2017, the Company shall use the same Settlement Method for all conversions occurring on the same Conversion Date, but the Company shall not have any obligation to use the same Settlement Method with respect to conversions that occur
on different Conversion Dates; provided that if the Company has not received the Stockholder Approvals prior to the relevant Settlement Method Election Date, the Company must settle any conversion of a Note by Cash Settlement in accordance
with Section 4.02(a)(ii). If the Company elects a Settlement Method, the Company shall inform the converting Holders (or in the case of any conversions occurring on or after January 1, 2017, the Company shall inform all Holders)

  
 -26-

 
through the Trustee, of the Settlement Method it has selected (x) in the case of any conversions occurring prior to January 1, 2017, no later than the close of business on the Trading
Day immediately following the related Conversion Date or (y) in the case of any conversions occurring on or after January 1, 2017, no later than January 1, 2017 (in either case, the “Settlement Method Election Date”).
In the event that the Company has received the Stockholder Approvals and has provided notice thereof to Holders pursuant to Section 4.02(a)(ii) prior to the relevant Settlement Method Election Date, if the Company does not elect a Settlement
Method prior to the deadline set forth in the immediately preceding sentence the Company shall no longer have the right to elect Cash Settlement or Physical Settlement, and shall be deemed to have elected Combination Settlement in respect of the
Conversion Obligation pursuant to Section 4.02(a), and the Specified Dollar Amount per $1,000 principal amount of Notes shall be equal to $1,000. If the Company has received the Stockholder Approvals prior to the relevant Settlement Method
Election Date, and the Company elects Combination Settlement but does not notify converting Holders prior to the deadline set forth in this Section 4.02(a)(i) of the Specified Dollar Amount per $1,000, such Specified Dollar Amount shall be
deemed to be $1,000. 
 (ii) Notwithstanding anything to the contrary in the Notes or this Indenture, the Company
shall not be permitted to elect Physical Settlement or Combination Settlement with respect to any conversion of Notes unless prior to the relevant Settlement Method Election Date the Company has received the Stockholder Approvals. With respect to
any conversion of a Note, if prior to the relevant Settlement Method Election Date (A) the Company has not received the Stockholder Approvals or (B) the Company has received the Stockholder Approvals but the Company has not elected a
Settlement Method pursuant to Section 4.02(a)(i) and has not notified Holders of its receipt of the Stockholder Approvals pursuant to the immediately succeeding sentence, Cash Settlement shall be deemed to apply. The Company shall notify
Holders by press release upon obtaining any such Stockholder Approvals. 
 (iii) Settlement amounts upon a
conversion of Notes shall be computed as follows: 
 (A) if the Company elects to satisfy its Conversion
Obligation in respect of such conversion by Physical Settlement, the Company shall deliver to the converting Holder in respect of each $1,000 principal amount of Notes being converted a number of shares of Common Stock equal to the Conversion Rate,
subject to Section 4.02(i); 
 (B) if the Company elects (or is deemed to have elected) to satisfy its
Conversion Obligation in respect of such conversion by Cash Settlement, the Company shall pay to the converting Holder in respect of each $1,000 principal amount of Notes being converted cash in an amount equal to the sum of the Daily Conversion
Values for each of the 40 consecutive Trading Days during the related Observation Period; and 

  
 -27-

 (C) if the Company elects (or is deemed to have elected) to satisfy its
Conversion Obligation in respect of such conversion by Combination Settlement, the Company shall pay or deliver, as the case may be, to the converting Holder in respect of each $1,000 principal amount of Notes being converted, a settlement amount
equal to the sum of the Daily Settlement Amounts for each of the 40 consecutive Trading Days during the related Observation Period, subject to Section 4.02(i). 

(iv) The Daily Settlement Amounts (if applicable) and the Daily Conversion Values (if applicable) shall be determined by
the Company promptly following the last day of the Observation Period. Promptly after such determination of the Daily Settlement Amounts or the Daily Conversion Values, as the case may be, and the amount of cash payable in lieu of any fractional
share, the Company shall notify the Trustee and the Conversion Agent (if other than the Trustee) of the Daily Settlement Amounts or the Daily Conversion Values, as the case may be, and the amount of cash payable in lieu of fractional shares of
Common Stock. 
 (b) Subject to Section 4.02(e), before any Holder of a Note shall be entitled to convert a Note as set
forth above, such Holder shall (i) in the case of a Certificated Note (A) complete and manually sign an irrevocable notice to the Conversion Agent as set forth in the Form of Conversion Notice attached to the Form of Note set forth in
Exhibit A hereto (a “Conversion Notice”) and state in writing therein the principal amount of Notes to be converted and the name or names (with addresses) in which such Holder wishes the certificate or certificates for any
shares of Common Stock to be delivered upon settlement of the Conversion Obligation to be registered and deliver such Conversion Notice to the Conversion Agent, (B) deliver such Note, duly endorsed to the Company or in blank (and accompanied by
appropriate endorsement and transfer documents), to the Conversion Agent and (C) if required, pay funds equal to interest payable on the next Interest Payment Date to which such Holder is not entitled as set forth in subsection (g) of this
Section 4.02 and (ii) in the case of a Global Note, comply with the Depositary’s procedures for converting a beneficial interest in a Global Note and, if required, pay funds equal to interest payable on the next Interest Payment Date
to which such Holder is not entitled as set forth in subsection (g) of this Section 4.02. The Trustee (and, if different, the Conversion Agent) shall notify the Company of any conversion pursuant to this Article 4 on the Conversion Date
for such conversion. No Conversion Notice with respect to any Notes may be surrendered by a Holder thereof if such Holder has also delivered a Repurchase Notice to the Company in respect of such Notes and not validly withdrawn such Repurchase Notice
in accordance with Section 3.02(c). 
 If more than one Note shall be surrendered for conversion at one time by the same
Holder, the Conversion Obligation with respect to such Notes shall be computed on the basis of the aggregate principal amount of the Notes (or specified portions thereof to the extent permitted hereby) so surrendered. 

(c) A Note shall be deemed to have been converted immediately prior to the close of business on the date (the “Conversion
Date”) that the Holder has complied with the requirements set forth in subsection (b) above. If the Company elects Physical Settlement with respect to any conversion of Notes, and (i) the relevant Conversion Date occurs after
June 15, 

  
 -28-

 
2017, the Company shall deliver the consideration due in respect of conversion on the Maturity Date or (ii) the relevant Conversion Date occurs on or prior to June 15, 2017, the Company
shall deliver the consideration due in respect of conversion on the third Business Day immediately following the relevant Conversion Date. If the Company elects (or is deemed to have elected) Cash Settlement or Combination Settlement with respect to
any conversion of Notes, except as set forth in Section 4.04(b) and Section 4.07(a), the Company shall deliver the consideration due in respect of conversion on the third Business Day immediately following the last Trading Day of the
relevant Observation Period. If any shares of Common Stock are due to converting Holders, the Company shall issue or cause to be issued, and deliver to the Conversion Agent or to such Holder, or such Holder’s nominee or nominees, certificates
or a book-entry transfer through the Depositary for the full number of shares of Common Stock to which such Holder shall be entitled in satisfaction of the Company’s Conversion Obligation. 

(d) In case any Note shall be surrendered for partial conversion, the Company shall execute and the Trustee shall authenticate and
deliver to or upon the written order of the Holder of the Note so surrendered a new Note or Notes in authorized denominations in an aggregate principal amount equal to the unconverted portion of the surrendered Note, without payment of any service
charge by the converting Holder but, if required by the Company or Trustee, with payment of a sum sufficient to cover any transfer tax or similar governmental charge required by law or that may be imposed in connection therewith as a result of the
name of the Holder of the new Notes issued upon such conversion being different from the name of the Holder of the old Notes surrendered for such conversion. 
 (e) If a Holder submits a Note for conversion, the Company shall pay any documentary, stamp or similar issue or transfer tax due on the issuance of any shares of Common Stock upon conversion of such Note,
unless the tax is due because the Holder requests such shares to be issued in a name other than the Holder’s name, in which case the Holder shall pay that tax. The Company or its stock transfer agent may refuse to deliver the certificates
representing the shares of Common Stock being issued in a name other than the Holder’s name until the Company or its representative receives a sum sufficient to pay any tax that is due by such Holder in accordance with the immediately preceding
sentence. 
 (f) Upon the conversion of an interest in a Global Note, the Trustee, or the Notes Custodian at the direction of
the Trustee, shall make a notation on such Global Note as to the reduction in the principal amount represented thereby. The Company shall notify the Trustee in writing of any conversion of Notes effected through any Conversion Agent other than the
Trustee. 
 (g) Except as described below, the Company shall not make any separate cash payment for accrued and unpaid interest,
if any, upon conversion of Notes. Upon conversion of a Note, the Company’s settlement of the Conversion Obligation in respect of such conversion shall be deemed to satisfy in full its obligation to pay the principal amount of such Note and
accrued and unpaid interest, if any, attributable to the period from, and including, June 28, 2011 or the most recent date to which interest has been paid or provided for to, but not including, the Conversion Date. As a result, accrued and
unpaid interest, if any, to, but not including, the Conversion Date shall be deemed to be paid in full rather than cancelled, extinguished or forfeited. Upon conversion of a Note into a combination of cash and shares of Common Stock, accrued and

  
 -29-

 
unpaid interest shall be deemed to be paid first out of the cash paid upon such conversion. Notwithstanding the foregoing, if a Note is submitted for conversion after the close of business on a
Regular Record Date, the Holder of such Note as of the close of business on such Regular Record Date shall receive the full amount of interest payable on such Note on the corresponding Interest Payment Date notwithstanding the conversion. A Note
surrendered for conversion during the period from the close of business on any Regular Record Date to the open of business on the immediately following Interest Payment Date must be accompanied by funds equal to the amount of interest payable on the
principal amount of the Note so converted; provided that no such payment need be made: 
 (i) for
conversions following the Regular Record Date immediately preceding the Maturity Date; 
 (ii) if the Company has
specified a Fundamental Change Repurchase Date that is after a Regular Record Date and on or prior to the corresponding Interest Payment Date; or 
 (iii) to the extent of any overdue interest, if any overdue interest exists at the time of conversion with respect to such Note. 
 (h) Each conversion shall be deemed to have been effected as to any Note surrendered for conversion on the Conversion Date; provided that the Person in whose name the certificate for any shares of
Common Stock issuable upon conversion is registered shall be treated as the holder of record of such shares as of the close of business on the relevant Conversion Date (if the Company elects to satisfy the related Conversion Obligation by Physical
Settlement) or the last Trading Day of the relevant Observation Period (if the Company elects, or is deemed to have elected, to satisfy the related Conversion Obligation by Combination Settlement), as the case may be. Upon the conversion of a Note,
the Person who surrendered such Note for conversion shall no longer be a Holder of such Note surrendered for conversion; provided that (x) if such Note was converted after the close of business on a Regular Record Date, the Holder of
such Note as of the close of business on such Regular Record Date shall have the right to receive the interest payable on such Note on the related Interest Payment Date in accordance with Section 4.02(g) and (y) the converting Holder shall
have the right to receive the consideration due upon conversion of such Note in accordance with this Section 4.02. 
 (i)
The Company shall not issue any fractional share of Common Stock upon conversion of the Notes and shall instead pay cash in lieu of any fractional share of Common Stock that would otherwise be issuable upon conversion based on the Daily VWAP on the
relevant Conversion Date (in the case of Physical Settlement) or based on the Daily VWAP on the last Trading Day of the relevant Observation Period (in the case of Combination Settlement). For each Note surrendered for conversion, if the Company has
elected (or is deemed to have elected) Combination Settlement, the full number of shares that shall be issued upon conversion thereof shall be computed on the basis of the aggregate Daily Settlement Amounts for the applicable Observation Period and
any fractional shares remaining after such computation shall be paid in cash. 

  
 -30-

 Section 4.03. Company to Provide Stock. The Company shall, prior to issuance of
any Notes hereunder and from time to time as may be necessary thereafter, reserve, provided that such reservation may be contingent upon receipt of the Stockholder Approvals, out of its authorized but unissued Common Stock, a sufficient number of
shares of Common Stock to permit the conversion of all outstanding Notes into shares of Common Stock (x) assuming that at the time of computation of such number of shares, all such Notes would be converted by a single Holder and that Physical
Settlement is applicable and (y) giving effect to the increase in the Conversion Rate that would result from the occurrence of a Make-Whole Fundamental Change with a Make-Whole Reference Date of the date of determination and a Stock Price equal
to the Minimum Stock Price. 
 All shares of Common Stock delivered upon conversion of the Notes shall be newly issued shares,
shall be duly authorized, validly issued, fully paid and nonassessable and shall be free from preemptive rights and free of any lien or adverse claim. 
 The Company shall endeavor promptly to comply with all federal and state securities laws regulating the offer and delivery of shares of Common Stock upon conversion of Notes, if any, and will list or
cause to have quoted such shares of Common Stock on each national securities exchange, over-the-counter market or such other market on which the Common Stock is then listed or quoted; provided, however, that if rules of such automated
quotation system or exchange permit the Company to defer the listing of such Common Stock until the first conversion of the Notes into Common Stock in accordance with the provisions of this Indenture, the Company covenants to list such Common Stock
issuable upon conversion of the Notes in accordance with the requirements of such automated quotation system or exchange at such time. 
 Section 4.04. Adjustment to Conversion Rate Upon a Make-Whole Fundamental Change. (a) If a Holder elects to convert its Notes in connection with a Make-Whole Fundamental Change, the
Conversion Rate shall, under certain circumstances, be increased by a number of additional shares (the “Additional Shares”), as described below. A conversion shall be deemed to be in connection with a Make-Whole Fundamental Change
if such conversion occurs on or after the Make-Whole Reference Date for such Make-Whole Fundamental Change and prior to the close of business on the Business Day immediately prior to the related Fundamental Change Repurchase Date (or in the case of
a Make-Whole Fundamental Change that does not constitute a Fundamental Change, the 35th Trading Day immediately following the applicable Make-Whole Reference Date). The Company shall notify Holders and the Trustee of the Make-Whole Reference Date
for any Make-Whole Fundamental Change, and issue a press release, on such Make-Whole Reference Date. 
 (b) Upon surrender of
Notes for conversion in connection with a Make-Whole Fundamental Change, the Company shall pay or deliver, as the case may be, the consideration due in respect of such converted Notes, based on the Conversion Rate as increased to reflect the
Additional Shares, if any, pursuant to the table set forth in clause (e) below in accordance with Section 4.02. However, if the consideration for the Common Stock in any Make-Whole Fundamental Change described in clause (b) of the
definition of Fundamental Change is composed entirely of cash, for any conversion of the Notes following the relevant Make-Whole Reference Date, the Conversion Obligation shall be calculated based solely on the Stock Price for the transaction and
the consideration due upon conversion shall be deemed to be an amount 

  
 -31-

 
in cash per $1,000 principal amount of converted Notes equal to the Conversion Rate (including any adjustment described in this Section 4.04), multiplied by such Stock Price. In such
event, the Conversion Obligation shall be determined and paid to Holders in cash on the third Business Day following the Conversion Date. 
 (c) The number of Additional Shares, if any, by which the Conversion Rate shall be increased for conversions in connection with a Make-Whole Fundamental Change shall be determined by reference to the
table set forth in clause (e) below, based on the date on which such Make-Whole Fundamental Change occurs or becomes effective (the “Make-Whole Reference Date”) and the price (the “Stock Price”) paid or deemed
paid per share of Common Stock in such Make-Whole Fundamental Change. If holders of Common Stock receive only cash consideration for their shares of Common Stock in connection with a Fundamental Change described in clause (b) of the definition
of Fundamental Change, the Stock Price shall be the cash amount paid per share of Common Stock. Otherwise, the Stock Price shall be the average of the Last Reported Sale Prices of Common Stock over the 10 Trading Day Period ending on the Trading Day
preceding the Make-Whole Reference Date. 
 (d) The Stock Prices set forth in the first column of the table in clause
(e) below (i.e., the row headers) shall be adjusted as of any date on which the Conversion Rate is adjusted pursuant to Section 4.05. The adjusted Stock Prices shall equal the Stock Prices applicable immediately prior to such
adjustment, multiplied by a fraction, the numerator of which is the applicable Conversion Rate in effect immediately prior to the adjustment giving rise to the Stock Price adjustment and the denominator of which is the applicable Conversion
Rate as so adjusted. The number of Additional Shares will be adjusted in the same manner, at the same time and for the same events as the Conversion Rate as set forth in Section 4.05. 

(e) The following table sets forth the increase, if any, to the Conversion Rate, expressed as number of Additional Shares per $1,000 in
principal amount of Notes, for conversions in connection with a Make-Whole Fundamental Change: 

  
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	 Make-Whole Reference Date

								
	 Stock Price
	 	 June 28, 2011
	 	 July 1, 2012
	 	 July 1, 2013
	 	 July 1, 2014
	 	 July 1, 2015
	 	 July 1, 2016
	 	 July 1, 2017

	 $32.41
	 	7.1202	 	7.1202	 	7.1202	 	7.1202	 	7.1202	 	7.1202	 	7.1202
	 $35.00
	 	6.0656	 	6.0136	 	5.9375	 	5.7788	 	5.4902	 	4.9727	 	4.8370
	 $40.00
	 	4.6146	 	4.4366	 	4.2096	 	3.8793	 	3.3877	 	2.5933	 	1.2656
	 $42.13
	 	4.1600	 	3.9519	 	3.6881	 	3.3199	 	2.7895	 	1.9599	 	0.0000
	 $45.00
	 	3.6593	 	3.4232	 	3.1289	 	2.7322	 	2.1818	 	1.3627	 	0.0000
	 $50.00
	 	3.0043	 	2.7484	 	2.4344	 	2.0305	 	1.5010	 	0.7890	 	0.0000
	 $60.00
	 	2.1913	 	1.9465	 	1.6554	 	1.3047	 	0.8869	 	0.4167	 	0.0000
	 $80.00
	 	1.4128	 	1.2302	 	1.0230	 	0.7894	 	0.5361	 	0.2723	 	0.0000
	 $100.00
	 	1.0345	 	0.9000	 	0.7491	 	0.5812	 	0.3993	 	0.2057	 	0.0000
	 $125.00
	 	0.7506	 	0.6553	 	0.5477	 	0.4274	 	0.2953	 	0.1526	 	0.0000
	 $150.00
	 	0.5664	 	0.4964	 	0.4164	 	0.3261	 	0.2262	 	0.1171	 	0.0000
	 $200.00
	 	0.3399	 	0.3003	 	0.2538	 	0.2000	 	0.1395	 	0.0725	 	0.0000

 The exact Stock Prices and Make-Whole Reference Dates may not be set forth in the table above, in which
case: 
 (i) if the Stock Price is between two Stock Price amounts in the table or the Make-Whole Reference Date
is between two dates in the table, the number of Additional Shares shall be determined by a straight-line interpolation between the number of Additional Shares set forth for the higher and lower Stock Price amounts and the two dates, as applicable,
based on a 365-day year; 
 (ii) if the Stock Price is greater than $200.00 per share, subject to adjustment in
the same manner as the Stock Prices set forth in the row headers of the table above, no increase shall be made to the Conversion Rate; and 
 (iii) if the Stock Price is less than $32.41 per share, subject to adjustment in the same manner as the Stock Prices set forth in the row headers of the table above (the “Minimum Stock
Price”), no increase shall be made to the Conversion Rate. 
 Notwithstanding the foregoing, in no event shall the
Conversion Rate exceed 30.8546 shares of Common Stock per $1,000 in principal amount of Notes, subject to adjustments in the same manner as the Conversion Rate as set forth in Section 4.05. 

Section 4.05. Conversion Rate Adjustments. The Conversion Rate shall be adjusted, from time to time by the Company, upon the
occurrence of any of the following events, except that the Company shall not make any adjustments to the Conversion Rate if Holders of the Notes have the right to participate (other than in the case of a share split or share combination), at the
same time and upon the same terms as holders of Common Stock and solely as a result of holding the Notes, in any of the transactions described in this Section 4.05, without having to convert their Notes as if they held a number of shares of
Common Stock equal to the Conversion Rate, multiplied by the principal amount (expressed in thousands) of Notes held by such Holder. 

  
 -33-

 (a) If the Company exclusively issues shares of Common Stock as a dividend or distribution
on shares of its Common Stock, or if the Company effects a share split or share combination, the Conversion Rate shall be adjusted based on the following formula: 
  

							
		 	CR1 = 
CR0 ×	 	OS1
	  	
	 	 	OS0	  	

  

					
	where,	  		  	
			
	CR0	  	=	  	the Conversion Rate in effect immediately prior to the open of business on the Ex-Dividend Date of such dividend or distribution, or immediately prior to the open of business on
the effective date of such share split or share combination, as applicable;
			
	CR1	  	=	  	the Conversion Rate in effect immediately after the open of business on such Ex-Dividend Date or effective date;
			
	OS0	  	=	  	the number of shares of Common Stock outstanding immediately prior to the open of business on such Ex-Dividend Date or effective date; and
			
	OS1	  	=	  	the number of shares of Common Stock outstanding immediately after giving effect to such dividend, distribution, share split or share combination.

 Any adjustment made under this Section 4.05(a) shall become effective immediately after the open of business on the
Ex-Dividend Date for such dividend or distribution, or immediately after the open of business on the effective date for such share split or share combination, as applicable. If any dividend or distribution of the type described in this
Section 4.05(a) is declared but not so paid or made, the Conversion Rate shall be immediately readjusted, effective as of the date the Board of Directors determines not to pay such dividend or distribution, to the Conversion Rate that would
then be in effect if such dividend or distribution had not been declared. The Company shall not pay any dividend or make any distribution on its Common Stock held in treasury, if any. 

(b) If the Company issues to all or substantially all holders of its Common Stock any rights, options or warrants entitling them, for a
period of not more than 45 calendar days after the announcement date of such issuance, to subscribe for or purchase shares of Common Stock at a price per share that is less than the average of the Last Reported Sale Prices of the Common Stock for
the 10 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the date of announcement of such issuance, the Conversion Rate shall be increased based on the following formula: 

 

							
		 	CR1 = 
CR0 ×	 	 
OS0 + X     
	  	
	 	 	 OS0 + Y     	  	

 where, 

  
 -34-

					
	CR0	  	=	  	the Conversion Rate in effect immediately prior to the open of business on the Ex-Dividend Date for such issuance;
			
	CR1	  	=	  	the Conversion Rate in effect immediately after the open of business on such Ex-Dividend Date;
			
	OS0	  	=	  	the number of shares of Common Stock outstanding immediately prior to the open of business on such Ex-Dividend Date;
			
	X	  	=	  	the total number of shares of Common Stock issuable pursuant to such rights, options or warrants; and
			
	Y	  	=	  	the number of shares of Common Stock equal to the aggregate price payable to exercise such rights, options or warrants, divided by the average of the Last Reported Sale
Prices of the Common Stock over the 10 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the date of announcement of the issuance of such rights, options or warrants.

 Any increase made under this Section 4.05(b) shall be made successively whenever any such rights, options or
warrants are issued and shall become effective immediately after the open of business on the Ex-Dividend Date for such issuance. To the extent that shares of the Common Stock are not delivered after the expiration of such rights, options or
warrants, the Conversion Rate shall be decreased to the Conversion Rate that would then be in effect had the increase with respect to the issuance of such rights, options or warrants been made on the basis of delivery of only the number of shares of
Common Stock actually delivered. If such rights, options or warrants are not so issued, the Conversion Rate shall be decreased to the Conversion Rate that would then be in effect if such Ex-Dividend Date for such issuance had not occurred.

 For purposes of this Section 4.05(b) and Section 4.01(d)(i), in determining whether any rights, options or warrants
entitle the holders to subscribe for or purchase shares of the Common Stock at less than such average of the Last Reported Sale Prices of the Common Stock for the 10 consecutive Trading Day period ending on, and including, the Trading Day
immediately preceding the date of announcement for such issuance, and in determining the aggregate offering price of such shares of Common Stock, there shall be taken into account any consideration received by the Company for such rights, options or
warrants and any amount payable on exercise or conversion thereof, the value of such consideration, if other than cash, to be determined by the Board of Directors. The Company shall not issue any such rights, options or warrants in respect of its
Common Stock held in treasury, if any. 
 (c) If the Company distributes shares of its Capital Stock, evidences of its
indebtedness or other assets or property of the Company to all or substantially all holders of the Common Stock, excluding (i) dividends, distributions or issuances covered in Section 4.05(a), Section 4.05(b) or Section 4.05(e),
(ii) dividends or distributions paid exclusively in cash covered in Section 4.05(d) and (iii) Spin-Offs as to which the provisions set forth below in this Section 4.05(c) shall apply (any of such shares of Capital Stock,
evidences of indebtedness, other assets or property, the “Distributed Property”), then the Conversion Rate shall be increased based on the following formula: 

  
 -35-

							
		 	CR1 = 
CR0 ×  	  	        SP0        	  	
	 	  	SP0 - FMV  	  	

 where, 
  

					
	CR0	 	=	  	the Conversion Rate in effect immediately prior to the open of business on the Ex-Dividend Date for such distribution;
			
	CR1	 	=	  	the Conversion Rate in effect immediately after the open of business on such Ex-Dividend Date;
			
	SP0	 	=	  	the average of the Last Reported Sale Prices of the Common Stock over the 10 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the
Ex-Dividend Date for such distribution; and
			
	FMV	 	=	  	the fair market value (as determined by the Board of Directors) of the Distributed Property with respect to each outstanding share of the Common Stock on the Ex-Dividend Date for
such distribution.

 Any increase made under the portion of this Section 4.05(c) above shall become effective
immediately after the open of business on the Ex-Dividend Date for such distribution. If such distribution is not so paid or made, the Conversion Rate shall be decreased to the Conversion Rate that would then be in effect if such dividend or
distribution had not been declared. Notwithstanding the foregoing, if “FMV” (as defined above) is equal to or greater than “SP0” (as defined above), in lieu of the foregoing increase, each Holder of a Note shall receive, in respect of each
$1,000 principal amount thereof, at the same time and upon the same terms as holders of the Common Stock receive the Distributed Property, the amount and kind of Distributed Property such Holder would have received if such Holder owned a number of
shares of Common Stock equal to the Conversion Rate in effect on the Ex-Dividend Date for the distribution. If the Board of Directors determines the “FMV” (as defined above) of any distribution for purposes of this Section 4.05(c) by
reference to the actual or when-issued trading market for any securities, it shall in doing so consider the prices in such market over the same period used in computing the Last Reported Sale Prices of the Common Stock over the 10 consecutive
Trading Day period ending on the Trading Day immediately preceding the Ex-Dividend Date for such distribution. 
 With respect
to an adjustment pursuant to this Section 4.05(c) where there has been a payment of a dividend or other distribution on the Common Stock of shares of Capital Stock of any class or series, or similar equity interest, of or relating to a
Subsidiary or other business unit of the Company, that are, or, when issued, will be, listed or admitted for trading on a U.S. national securities exchange (a “Spin-Off”), the Conversion Rate shall be increased based on the
following formula: 
  

							
		 	CR1 = 
CR0 ×  	  	        FMV0 + MP0        	  	
	 	  	MP0	  	

  
 -36-

 where, 
  

					
	CR0	 	=	  	the Conversion Rate in effect immediately prior to the open of business on the Ex-Dividend Date for such Spin-Off;
			
	CR1	 	=	  	the Conversion Rate in effect immediately after the open of business on the Ex-Dividend Date for such Spin-Off;
			
	FMV0	 	=	  	the average of the Last Reported Sale Prices of the Capital Stock or similar equity interest distributed to holders of the Common Stock applicable to one share of the Common
Stock (determined by reference to the definition of Last Reported Sale Price as if references therein to Common Stock were to such Capital Stock or similar equity interest) over the first 10 consecutive Trading Day period after, and including, the
Ex-Dividend Date of the Spin-Off (the “Valuation Period”); and
			
	MP0	 	=	  	the average of the Last Reported Sale Prices of the Common Stock over the Valuation Period.

 The adjustment to the Conversion Rate under the preceding paragraph shall be determined on the last Trading Day of the
Valuation Period but shall be given effect immediately after the open of business on the Ex-Divided Date for the Spin-Off; provided that in respect of any conversion during the Valuation Period, references in the portion of this
Section 4.05(c) related to Spin-Offs to 10 Trading Days shall be deemed to be replaced with such lesser number of Trading Days as have elapsed between the Ex-Dividend Date of such Spin-Off and the Conversion Date in determining the Conversion
Rate. If the Ex-Dividend Date for the Spin-Off is less than 10 Trading Days prior to, and including, the end of the Observation Period in respect of any conversion, references in the preceding paragraph to 10 Trading Days shall be deemed replaced,
for purposes of calculating the daily Conversion Rates for such conversion, with such lesser number of Trading Days as have elapsed from, and including, the Ex-Dividend Date for such Spin-Off to, and including, the last Trading Day of such
Observation Period. If any such dividend or distribution described in this Section 4.05(c) is declared but not paid or made, the new Conversion Rate shall be decreased to be the Conversion Rate that would then be in effect if such dividend or
distribution had not been declared. 
 (d) If any cash dividend or distribution is made to all or substantially all holders of
the Common Stock (other than distributions described in Section 4.05(e)), the Conversion Rate shall be adjusted based on the following formula: 
  

							
		 	CR1 = 
CR0 ×  	  	        SP0        	  	
	 	  	SP0 - C	  	

 where, 
  

					
	CR0	 	=	  	the Conversion Rate in effect immediately prior to the open of business on the Ex-Dividend Date for such dividend or distribution;

  
 -37-

					
	CR1	 	=	  	the Conversion Rate in effect immediately after the open of business on the Ex-Dividend Date for such dividend or distribution;
			
	SP0	 	=	  	the Last Reported Sale Price of the Common Stock on the Trading Day immediately preceding the Ex-Dividend Date for such dividend or distribution; and
			
	C	 	=	  	the amount in cash per share the Company distributes to holders of its Common Stock.

 Any increase pursuant to this Section 4.05(d) shall become effective immediately after the open
of business on the Ex-Dividend Date for such dividend or distribution. If such dividend or distribution is not so paid, the Conversion Rate shall be decreased, effective as of the date the Board of Directors determines not to make or pay such
dividend or distribution, to the Conversion Rate that would then be in effect if such dividend or distribution had not been declared. Notwithstanding the foregoing, if “C” (as defined above) is equal to or greater than “SP0” (as defined above), in lieu of the foregoing increase, each Holder
of a Note shall receive, for each $1,000 principal amount of Notes, at the same time and upon the same terms as holders of shares of the Common Stock, the amount of cash that such Holder would have received if such Holder owned a number of shares of
Common Stock equal to the Conversion Rate on the Ex-Dividend Date for such cash dividend or distribution. 
 (e) If the Company
or any of its Subsidiaries makes a payment in respect of a tender or exchange offer for the Common Stock (subject to the tender offer rules under the Exchange Act then applicable), to the extent that the cash and value of any other consideration
included in the payment per share of the Common Stock exceeds the average of the Last Reported Sale Prices of Common Stock over the 10 consecutive Trading Day period commencing on, and including, the Trading Day next succeeding the last date on
which tenders or exchanges may be made pursuant to such tender or exchange offer, the Conversion Rate shall be increased based on the following formula: 
  

							
		 	CR1 = 
CR0 ×  	    	        AC + (SP1 × OS1)        	  	
		 	    	OS0 ×
SP1	  	

 where, 
  

					
	CR0	 	=	  	the Conversion Rate in effect immediately prior to the open of business on the Trading Day next succeeding the date such tender or exchange offer expires;
			
	CR1	 	=	  	the Conversion Rate in effect immediately after the open of business on the Trading Day next succeeding the date such tender or exchange offer expires;
			
	AC	 	=	  	the aggregate value of all cash and any other consideration (as determined by the Board of Directors) paid or payable for shares of Common Stock purchased in such tender or
exchange offer;

  
 -38-

					
	OS0	 	=	  	the number of shares of Common Stock outstanding immediately prior to the date such tender or exchange offer expires (prior to giving effect to the purchase of all shares of
Common Stock accepted for purchase or exchange in such tender or exchange offer);
			
	OS1	 	=	  	the number of shares of Common Stock outstanding immediately after the date such tender or exchange offer expires (after giving effect to the purchase of all shares of Common
Stock accepted for purchase or exchange in such tender or exchange offer); and
			
	SP1	 	=	  	the average of the Last Reported Sale Prices of Common Stock over the 10 consecutive Trading Day period commencing on, and including, the Trading Day next succeeding the date
such tender or exchange offer expires.

 The adjustment to the Conversion Rate under this Section 4.05(e) shall be determined at the close of business on the
10th Trading Day immediately following, and including, the Trading Day next succeeding the date such tender or exchange offer expires but shall be given effect immediately after the open of business on the Trading Day next succeeding the date such
tender or exchange offer expires; provided that in respect of any conversion within the 10 Trading Days immediately following, and including, the expiration date of any tender or exchange offer, references with respect to 10 Trading Days
shall be deemed replaced with such lesser number of Trading Days as have elapsed between the expiration date of such tender or exchange offer and the Conversion Date in determining the Conversion Rate. If the Trading Day immediately following the
date the tender or exchange offer expires is less than 10 Trading Days prior to, and including, the end of the Observation Period in respect of any conversion, references in this Section 4.05(e) to 10 Trading Days shall be deemed replaced, for
purposes of calculating the affected daily Conversion Rates for such conversion, with such lesser number of Trading Days as have elapsed from, and including, the Trading Day immediately following the date such tender or exchange offer expires to,
and including, the last Trading Day of such Observation Period. 
 (f) Notwithstanding this Section 4.05 or any other
provision of this Indenture or the Notes, if a Conversion Rate adjustment becomes effective on any Ex-Dividend Date, and a Holder that has converted its Notes on or after such Ex-Dividend Date and on or prior to the related Record Date would be
treated as the record holder of the Common Stock as of the related Conversion Date as described under Section 4.02(h) based on an adjusted Conversion Rate for such Ex-Dividend Date, then, notwithstanding the Conversion Rate adjustment
provisions in this Section 4.05, the Conversion Rate adjustment relating to such Ex-Dividend Date shall not be made for such converting Holder. Instead, such Holder shall be treated as if such Holder were the record owner of the shares of
Common Stock on an unadjusted basis and participate in the related dividend, distribution or other event giving rise to such adjustment. 
 (g) Except as stated herein, the Company shall not adjust the Conversion Rate for the issuance of shares of its Common Stock or any securities convertible into or exchangeable for shares of its Common
Stock or the right to purchase shares of its Common Stock or such convertible or exchangeable securities. 

  
 -39-

 (h) In addition to those adjustments required by subsections (a), (b), (c), (d) and
(e) of this Section 4.05 and Section 4.04, and to the extent permitted by applicable law and subject to the applicable rules of The NASDAQ Global Select Market and any other securities exchange on which the Common Stock is then
listed, the Company from time to time may increase the Conversion Rate by any amount for a period of at least 20 days if the Board of Directors has determined that such increase would be in the Company’s best interest, and any such
determination by the Board of Directors shall be conclusive. In addition, the Company may (but is not required to) increase the Conversion Rate, as the Board of Directors considers advisable, to avoid or diminish any income tax to holders of Common
Stock or rights to purchase Common Stock resulting from any dividend or distribution of stock (or rights to acquire stock) or from any event treated as such for tax purposes. Whenever the Conversion Rate is increased pursuant to either of the
preceding two sentences, the Company shall mail to the Trustee and the Holder of each Note at its last address appearing on the register of the Primary Registrar a notice of the increase (x) at least 15 days prior to the date the increased
Conversion Rate takes effect and (y) otherwise in accordance with applicable law, and such notice shall state the increased Conversion Rate and the period during which it will be in effect. 

(i) Except as described in this Section 4.05 or in Section 4.04, the Company shall not adjust the Conversion Rate. Without
limiting the foregoing, the applicable Conversion Rate shall not be adjusted: 
 (i) upon the issuance of any
shares of Common Stock pursuant to any present or future plan providing for the reinvestment of dividends or interest payable on the Company’s securities and the investment of additional optional amounts in shares of Common Stock under any
plan; 
 (ii) upon the issuance of any shares of Common Stock or options or rights to purchase or acquire those
shares pursuant to any present or future employee, director or consultant benefit plan or program of or assumed by the Company or any of its Subsidiaries; 
 (iii) upon the issuance of any shares of Common Stock pursuant to any option, warrant, right or exercisable, exchangeable or convertible security not described in clause (ii) of this subsection
(i) and outstanding prior to the date the Notes were first issued; 
 (iv) for a change solely in the par
value of the Common Stock; or 
 (v) for accrued and unpaid interest. 

(j) All calculations, adjustments and other determinations in respect of the applicable Conversion Rate shall be made by the Company to
the nearest 1/10,000th of a share. No adjustment to the Conversion Rate shall be required unless the adjustment would require an increase or decrease of at least 1% of the Conversion Rate. However, the Company shall carry forward any adjustments
that are less than 1% of the Conversion Rate that the Company elects not to make and take them into account upon (i) any conversion of Notes, (ii) each Trading Day of any Observation Period and (iii) such times as all adjustments that
have not been made prior thereto would have the effect of adjusting the Conversion Rate by at least 1%. 

  
 -40-

 (k) Whenever the Conversion Rate is adjusted pursuant to this Section 4.05, the Company
shall compute the adjusted Conversion Rate in accordance with this Section 4.05 and shall prepare an Officers’ Certificate setting forth (i) the adjusted Conversion Rate, (ii) the subsection of this Section 4.05 pursuant to
which such adjustment has been made, showing in reasonable detail the facts upon which such adjustment is based, (iii) the calculation of such adjustment and (iv) the date as of which such adjustment is effective, and such Officers’
Certificate shall promptly be delivered to the Trustee (in accordance with Section 14.02) and each Conversion Agent (which certificates shall be conclusive evidence of the accuracy of such adjustment absent manifest error). As soon as
practicable after each such adjustment, the Company shall deliver to the Holders a notice stating that the Conversion Rate has been adjusted and setting forth the adjusted Conversion Rate. Unless and until a Responsible Officer of the Trustee shall
receive an Officers’ Certificate with respect to an adjustment of the Conversion Rate, the Trustee may assume without inquiry that the Conversion Rate has not been adjusted and that the last Conversion Rate of which it has knowledge remains in
effect. Neither the Trustee nor any Conversion Agent shall be under any duty or responsibility with respect to any such certificate or the information and calculations contained therein, except to exhibit the same to any Holder of Notes desiring
inspection thereof at its office during normal business hours. 
 (l) For purposes of this Section 4.05, the number of
shares of Common Stock at any time outstanding shall not include shares held in the treasury of the Company so long as the Company does not pay any dividend or make any distribution on shares of Common Stock held in the treasury of the Company, but
shall include shares issuable in respect of scrip certificates issued in lieu of fractions of shares of Common Stock. 

Section 4.06. Adjustments of Prices. Whenever any provision of this Indenture requires the Company to calculate the Last
Reported Sale Prices, the Daily VWAPs, the Daily Conversion Values or the Daily Settlement Amounts over a span of multiple days (including an Observation Period and the period for determining the Stock Price for purposes of a Make-Whole Fundamental
Change), the Board of Directors shall make appropriate adjustments to each to account for any adjustment to the Conversion Rate that becomes effective, or any event requiring an adjustment to the Conversion Rate where the Ex-Dividend Date, effective
date or expiration date of the event occurs, at any time during the period when the Last Reported Sale Prices, the Daily VWAPs, the Daily Conversion Values or the Daily Settlement Amounts are to be calculated. 

Section 4.07. Effect of Recapitalizations, Reclassifications and Changes of the Common Stock. (a) In the event of:

 (i) any Fundamental Change described in clause (b) of the definition thereof; 

(ii) any reclassification of the Common Stock; 

(iii) a consolidation, binding share exchange, recapitalization, reclassification, merger, combination or other similar
event; or 
 (iv) a sale or conveyance to another Person of all or substantially of the Company’s property
and assets, 

  
 -41-

 in each case, as a result of which the Common Stock would be converted into, or exchanged for, cash,
securities or other property (including cash or any combination thereof) (any such event, a “Merger Event”), Holders shall be entitled to convert each $1,000 principal amount of Notes into the same type of consideration that Holders
would have been entitled to receive if such Holders had held a number of shares of Common Stock equal to the applicable Conversion Rate in effect immediately prior to such Merger Event (such consideration, the “Reference Property”,
with each “unit of Reference Property” meaning the kind and amount of Reference Property that a holder of one share of Common Stock is entitled to receive) and, if immediately following such Merger Event (i) any Person other
than, or in addition to, NuVasive, Inc. would be an obligor on the Notes or (ii) the Reference Property would include any shares of stock or other securities issued by any Person other than NuVasive, Inc., then prior to or at the effective time
of such Merger Event, the Company or the successor or purchasing Person, as the case may be, shall execute with the Trustee a supplemental indenture permitted under Section 10.01(j) providing for such change in the right to convert each $1,000
principal amount of Notes; provided, however, that at and after the effective time of the Merger Event (A) if the Company has received the Stockholder Approvals prior to the relevant Settlement Method Election Date, the Company
shall have the right to determine the form of consideration to be paid or delivered, as the case may be, upon conversion of Notes in accordance with Section 4.02 and (B)(I) any amount payable in cash upon conversion of the Notes in accordance
with Section 4.02 shall continue to be payable in cash, (II) any shares of Common Stock that the Company would have been required to deliver upon conversion of the Notes in accordance with Section 4.02 shall instead be deliverable in the
amount and type of Reference Property that a holder of that number of shares of Common Stock would have been entitled to receive in such Merger Event and (III) the Daily VWAP shall be calculated based on the value of a unit of Reference
Property in such Merger Event. 
 For purposes of the foregoing, if the Merger Event causes the Common Stock to be converted
into, or exchanged for, more than a single type of consideration, determined based in part upon any form of stockholder election, then the Reference Property will be deemed to be (x) the weighted average of the types and amounts of
consideration received by the holders of Common Stock that affirmatively make such an election or (y) if no holders of Common Stock affirmatively make such an election, the types and amount of consideration actually received by such holders.
The Company shall notify Holders, the Trustee and the Conversion Agent (if other than the Trustee) of the weighted average as soon as practicable after such determination is made. 

If the holders receive only cash in any such Merger Event, then for all conversions that occur after the effective date of such Merger
Event (x) the consideration due upon conversion of each $1,000 principal amount of Notes shall be solely cash in an amount equal to the Conversion Rate in effect on the Conversion Date (as may be increased by any Additional Shares pursuant to
Section 4.04), multiplied by the price paid per share of Common Stock in such Merger Event and (y) the Company shall satisfy its Conversion Obligation by paying such cash to converting Holders on the third Business Day immediately
following the relevant Conversion Date. 
 Any supplemental indenture described in the third immediately preceding paragraph
shall provide for adjustments that shall be as nearly equivalent as is possible to the adjustments provided for in this Article 4. If, in the case of any Merger Event, the Reference Property 

  
 -42-

 
includes shares of stock, securities or other property or assets (including cash or any combination thereof) of a Person other than the successor or purchasing corporation, as the case may be, in
such Merger Event, then such supplemental indenture shall also be executed by such other Person and shall contain such additional provisions to protect the interests of the Holders of the Notes as the Board of Directors shall reasonably consider
necessary by reason of the foregoing, including to the extent required by the Board of Directors and practicable the provisions providing for the repurchase rights set forth in Article 3. 

(b) In the event the Company shall execute a supplemental indenture pursuant to subsection (a) of this Section 4.07, the
Company shall promptly file with the Trustee an Officers’ Certificate briefly stating the reasons therefor, the kind or amount of cash, securities or property or asset that will comprise the Reference Property after any such Merger Event, any
adjustment to be made with respect thereto and that all conditions precedent have been complied with, and shall promptly mail notice thereof to all Holders. The Company shall cause notice of the execution of such supplemental indenture to be mailed
to each Holder, at its address appearing on the register of the Primary Registrar provided for in this Indenture, within 20 days after execution thereof. Failure to deliver such notice shall not affect the legality or validity of such supplemental
indenture. 
 (c) The Company shall not become a party to any Merger Event unless its terms are consistent with this
Section 4.07. None of the foregoing provisions shall affect the right of a Holder of Notes to convert its Notes into cash, shares of Common Stock or a combination of cash and shares of Common Stock, as applicable, as set forth in
Section 4.01 and Section 4.02 prior to the effective date of such Merger Event. 
 (d) The above provisions of this
Section 4.07 shall similarly apply to successive Merger Events. 
 Section 4.08. Conversion of Beneficial Interests
in Global Notes. Upon conversions of beneficial interests in any Global Note, the Trustee or the Notes Custodian, at the direction of the Trustee, shall reduce the aggregate principal amount of outstanding Notes represented by such Global Note
to reflect the conversion. 
 Section 4.09. Stockholders Rights. To the extent that the Company has a rights plan in
effect upon any conversion of a Note, if Combination Settlement or Physical Settlement applies to such conversion, the converting Holder shall receive, in addition to any Common Stock and in lieu of any adjustment to the Conversion Rate, the
appropriate number of rights, if any, as may be provided by the terms of any such stockholder rights plan, as the same may be amended from time to time, unless prior to such conversion, the rights have separated from the shares of Common Stock in
accordance with the provisions of the applicable stockholder rights plan, in which case the Conversion Rate shall be adjusted at the time of separation as if the Company distributed to all holders of Common Stock shares of Capital Stock of the
Company, evidences of its indebtedness, assets or property as provided in Section 4.05(c), subject to readjustment in the event of the expiration, termination or redemption of such rights. 

Section 4.10. Trustee’s Disclaimer. The Trustee shall have no duty to determine when an adjustment under this Article 4
should be made, how it should be made or what such 

  
 -43-

 
adjustment should be, but may accept as conclusive evidence of that fact or the correctness of any such adjustment, and shall be protected in relying upon, the Officers’ Certificate that the
Company is obligated to deliver to the Trustee pursuant to Section 4.05(k). The Trustee makes no representation as to the validity or value of any securities or assets issued upon conversion of Notes, and the Trustee shall not be responsible
for the Company’s failure to comply with any provisions of this Article 4. The Trustee and the Conversion Agent (if other than the Trustee) shall have no responsibility for determination of the Daily Settlement Amounts (if applicable) or the
Daily Conversion Values (if applicable). In addition, in no event shall the Trustee or Conversion Agent be responsible for making any calculations under this Indenture or for determining amounts to be paid or for monitoring any Stock Price. For the
avoidance of doubt, the Trustee and Conversion Agent shall rely conclusively on the calculations and information provided to them by the Company as to the Daily VWAP, Daily Conversion Value, Last Reported Sale Prices, accrued interest payable on the
Notes and the Conversion Rate. The Company shall make all such calculations in good faith and, absent manifest error, the Company’s calculations shall be final and binding on Holders of Notes. The Company shall provide a schedule of its
calculations to each of the Trustee and the Conversion Agent, and the Trustee will forward the Company’s calculations to any Holder of Notes upon the request of that Holder at the sole cost and expense of the Company. 

Neither the Trustee nor the Conversion Agent shall be charged with knowledge of or have any duties to monitor any Measurement Period or
Observation Period. 
 The Trustee shall not be under any responsibility to determine the correctness of any provisions
contained in any supplemental indenture executed pursuant to Section 6.01, but may accept as conclusive evidence of the correctness thereof, and shall be fully protected in relying upon, the Officers’ Certificate with respect thereto which
the Company is obligated to file with the Trustee pursuant to Section 6.01. 
 ARTICLE 5 

COVENANTS 
 Section 5.01. Payment on the Notes. The Company shall make all payments in respect of the Notes on the dates and in the manner provided in the Notes and this Indenture. Principal (including
the Fundamental Change Repurchase Price, if applicable) of and interest on the Notes shall be considered paid on the date it is due, if the Paying Agent (if other than the Company or an Affiliate thereof) holds as of 5:00 p.m., New York City time,
on the due date money, deposited by the Company or an Affiliate thereof in immediately available funds, designated for and sufficient to pay all principal (including the Fundamental Change Repurchase Price) and interest then due on the Notes,
subject to Section 9.04. 
 Section 5.02. SEC Reports. (a) The Company shall file with the Trustee within
15 days after the same are required to be filed with the SEC, copies of any documents or reports that the Company is required to file with the SEC pursuant to Section 13 or 15(d) of the Exchange Act. Any such document or report that the Company
files with the SEC via the EDGAR system shall be deemed filed with the Trustee for purposes of this Section 5.02 at the time such documents are filed via EDGAR. The Company shall at all times comply with TIA Section 314(a). 

  
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 (b) Delivery of such reports, information and documents to the Trustee is for informational
purposes only and the Trustee’s receipt of such shall not constitute constructive notice of any information contained therein or determinable from information contained therein, including the Company’s compliance with any of its covenants
hereunder (as to which the Trustee is entitled to rely exclusively on Officers’ Certificates). 
 Section 5.03.
Compliance Certificates. (a) The Company shall deliver to the Trustee, within 120 days after the end of each fiscal year during which any Notes are outstanding, an Officers’ Certificate stating whether or not the signers thereof know
of any Default or Event of Default that occurred during such fiscal year and is continuing. Such Officers’ Certificate shall contain a certification from the principal executive officer, principal financial officer or principal accounting
officer of the Company that a review has been conducted of the activities of the Company and the Company’s performance under this Indenture and that the Company has complied with all conditions and covenants under this Indenture. For purposes
of this Section 5.03, such compliance shall be determined without regard to any period of grace or requirement of notice provided under this Indenture. If either Officer of the Company signing such Officers’ Certificate has knowledge of
such a Default or Event of Default, the Officers’ Certificate shall describe any such Default or Event of Default and its status. 
 (b) The Company shall, so long as any of the Notes are outstanding, deliver to the Trustee, within 30 days after the occurrence thereof, written notice, in accordance with Section 14.02 and making
specific reference to this Indenture, of any events that would constitute a Default, the status of those events and what action the Company is taking or proposes to take in respect thereof. 

Section 5.04. Further Instruments and Acts. Upon request of the Trustee, the Company will execute and deliver such further
instruments and do such further acts as may be reasonably necessary or proper to carry out more effectively the purposes of this Indenture. 
 Section 5.05. Maintenance of Corporate Existence. Subject to Article 6, the Company will do or cause to be done all things necessary to preserve and keep in full force and effect its corporate
existence. 
 Section 5.06. Stay, Extension and Usury Laws. The Company covenants (to the extent that it may
lawfully do so) that it shall not at any time insist upon, plead, or in any manner whatsoever claim or take the benefit or advantage of, any stay, extension or usury law or other law which would prohibit or forgive the Company from paying all or any
portion of the principal of or interest on the Notes as contemplated herein, wherever enacted, now or at any time hereafter in force, or which may affect the covenants or the performance of this Indenture, and the Company (to the extent it may
lawfully do so) hereby expressly waives all benefit or advantage of any such law and covenants that it will not, by resort to any such law, hinder, delay or impede the execution of any power herein granted to the Trustee, but will suffer and permit
the execution of every such power as though no such law had been enacted. 
 Section 5.07. Appointments to Fill
Vacancies in Trustee’s Office. The Company, whenever necessary to avoid or fill a vacancy in the office of Trustee, will appoint, in the manner provided in Section 8.10, a Trustee, so that there shall at all times be a Trustee
hereunder. 

  
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 ARTICLE 6 
 CONSOLIDATION, MERGER AND SALE OF ASSETS 
 Section 6.01. Company May Consolidate, Etc, Only on Certain Terms. The Company shall not consolidate with or merge with or into, or sell, convey, transfer or lease all or substantially all of
its properties and assets to another Person, unless: 
 (a) the resulting, surviving or transferee Person (the
“Successor Company”), if not the Company, is an entity organized and existing under the laws of the United States of America, any State thereof or the District of Columbia and the Successor Company (if other than the Company)
expressly assumes, by an indenture supplemental hereto all of the obligations of the Company under the Notes and this Indenture; 
 (b) immediately after giving effect to such transaction, no Default or Event of Default has occurred and is continuing under this Indenture; and 

(c) the Company has delivered to the Trustee an Officers’ Certificate or an Opinion of Counsel, each stating that such
consolidation, merger, sale, conveyance, transfer or lease and, if a supplemental indenture is required in connection with such transaction, such supplemental indenture, complies with this Article 6 and that all conditions precedent herein provided
for relating to such transaction have been complied with. 
 Section 6.02. Successor Substituted. Upon any such
consolidation, merger, sale, conveyance, transfer or lease, the Successor Company (if other than the Company) shall succeed to, and may exercise every right and power of, the Company under this Indenture and the Notes with the same effect as if such
Successor Company had been named as the Company herein, and after such transaction, except in the case of a lease of all or substantially all of the Company’s properties and assets, if the predecessor Person is still in existence, such
predecessor Person shall be released from its obligations and covenants under this Indenture and the Notes. 
 ARTICLE 7

 DEFAULT AND REMEDIES 

Section 7.01. Events Of Default. Each of the following events is an “Event of Default”: 

(1) default by the Company in any payment of interest on any Note when due and payable and such default continues for a period of 30
days; 
 (2) default by the Company in the payment of principal of any Note when due and payable on the Maturity Date, upon any
required repurchase, upon acceleration (subject to the right of Holders, under certain conditions, to rescind any such acceleration, in accordance with Section 7.02) or otherwise; 

(3) failure by the Company to comply with its obligation to convert any Note in accordance with this Indenture upon exercise of a
Holder’s conversion right; 
 (4) failure by the Company to comply with its obligations set forth in Article 6; 

  
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 (5) failure by the Company to comply with its notice obligations pursuant to
Section 3.02(b), Section 4.01(d) or Section 4.01(e), in each case within the time periods specified therein, if such failure continues for five Business Days; 
 (6) failure by the Company for 60 days after written notice from the Trustee or the Holders of at least 25% in principal amount of the Notes then outstanding has been received by the Company to comply
with any of its other agreements contained in the Notes or this Indenture; 
 (7) indebtedness for money borrowed by the Company
or any Significant Subsidiary of the Company in excess of $30 million in the aggregate, whether such debt now exists or shall hereafter be created, is not paid by the Company or any such Significant Subsidiary at final maturity or upon acceleration
and such indebtedness is not discharged, or such acceleration is not cured or rescinded, within a period of 30 days after the occurrence of such debt becoming or being declared due and payable or such failure to pay, as the case may be; 

(8) failure by the Company or any of its majority-owned Subsidiaries, within 30 days, to pay, bond or otherwise discharge any judgments
or orders for the payment of money the total uninsured amount of which for the Company or any of its Subsidiaries exceeds in the aggregate $30 million, which are not stayed on appeal; 

(9) the Company or any of its Significant Subsidiaries shall commence a voluntary case or other proceeding seeking liquidation,
reorganization or other relief with respect to itself or its debts under any bankruptcy, insolvency or other similar law now or hereafter in effect or seeking the appointment of a trustee, receiver, liquidator, custodian or other similar official of
the Company or any of its Significant Subsidiaries or any substantial part of its respective property, or shall consent to any such relief or to the appointment of or taking possession by any such official in an involuntary case or other proceeding
commenced against it, or shall make a general assignment for the benefit of creditors, or shall fail generally to pay its debts as they become due; or 
 (10) an involuntary case or other proceeding shall be commenced against the Company or any of its Significant Subsidiaries seeking liquidation, reorganization or other relief with respect to it or its
debts under any bankruptcy, insolvency or other similar law now or hereafter in effect or seeking the appointment of a trustee, receiver, liquidator, custodian or other similar official of the Company or any of its Significant Subsidiaries or any
substantial part of its respective property, and such involuntary case or other proceeding shall remain undismissed and unstayed for a period of sixty (60) consecutive calendar days. 

Section 7.02. Acceleration. If an Event of Default (other than an Event of Default specified in clause (9) or
(10) of Section 7.01 with respect to the Company) occurs and is continuing, the Trustee may, by notice to the Company, or the Holders of at least 25% in principal amount of the Notes then outstanding may, by notice to the Company and the
Trustee, and the Trustee at the request of such Holders shall, declare 100% of the principal of and accrued and unpaid interest on all the Notes then outstanding to be due and payable. Upon such a declaration of acceleration, all principal and
accrued and unpaid interest on the Notes shall be due and payable immediately. Upon an Event of Default arising out of clause (9) or (10) of 

  
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Section 7.01 (except with respect to any Significant Subsidiary), the aggregate principal amount of, and accrued and unpaid interest on, the Notes shall become and be due and payable
immediately without any declaration or other act on the part of the Trustee or any Holder. After any acceleration, but before a judgment or decree based on acceleration, the Holders of a majority in aggregate principal amount of the Notes may,
except with respect to the uncured nonpayment of principal or interest or with respect to the failure to pay and/or deliver the consideration due upon conversion, rescind and annul such acceleration by notice to the Trustee if (a) the
rescission would not conflict with any judgment or decree of a court of competent jurisdiction and (b) all existing Events of Default, other than the uncured non-payment of the principal of and interest on the notes that have become due solely
by such declaration of acceleration, have been cured or waived. No such rescission shall affect any subsequent default or impair any right consequent thereto. 
 Section 7.03. Other Remedies. Subject to Section 7.02 and Article 8, if an Event of Default occurs and is continuing, the Trustee may, but shall be under no obligation to, pursue any
available remedy by proceeding at law or in equity to collect the payment of the principal of or interest on the Notes or to enforce the performance of any provision of the Notes or this Indenture. 

The Trustee may maintain a proceeding even if it does not possess any of the Notes or does not produce any of them in the proceeding. A
delay or omission by the Trustee or any Holder in exercising any right or remedy accruing upon an Event of Default shall not impair the right or remedy or constitute a waiver of or acquiescence in the Event of Default. No remedy is exclusive of any
other remedy. All available remedies are cumulative to the extent permitted by law. 
 Section 7.04. Extension Fee.
(a) Notwithstanding anything in this Indenture or in the Notes to the contrary, if the Company so elects, the sole remedy for Holders for an Event of Default relating to any obligations the Company may have or is deemed to have pursuant to
Section 314(a)(1) of the TIA or Section 5.02(a) shall for the first 180 days after the occurrence of such Event of Default consist exclusively of the right (the “Extension Right”) to receive an extension fee on the Notes
equal to 0.25% of the principal amount of the Notes (the “Extension Fee”). On the 181st day after such Event of Default (if such violation is not cured or waived prior to such 181st day), the Notes shall be subject to acceleration
as provided in Section 7.02. 
 (a) Notwithstanding the provisions of Section 7.04(a), if an event of default occurs
under any other series of the Company’s debt securities issued subsequent to the date hereof resulting from the Company’s failure to file any documents or reports that the Company is required to file with the SEC pursuant to
Section 13 or 15(d) of the Exchange Act and such event of default is not subject to extension on terms similar to the terms set forth in Section 7.04(a) above and results in the principal amount of such debt securities becoming due and
payable, then the Extension Right will no longer apply and the Notes will be subject to acceleration as provided in Section 7.02. 
 (b) In order to exercise the Extension Right and elect to pay Extension Fee as the sole remedy during the first 180 days after the occurrence of any Event of Default relating to the failure to comply
with the reporting obligations of the Company under Section 314(a)(1) of the 

  
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TIA or Section 5.02(a) in accordance with subsection (a) of this Section 7.04 and this subsection (c), the Company must (i) notify all Holders of the Notes and the Trustee and
Paying Agent of such election and (ii) pay such Extension Fee, in each case on or before the close of business on the date on which such Event of Default occurs. Upon the Company’s failure to timely give such notice or pay the Extension
Fee when due, the Notes shall be immediately subject to acceleration as provided in Section 7.02. 
 Section 7.05.
Waiver of Defaults and Events of Default. Subject to Section 7.08, the Holders of a majority in principal amount of the Notes then outstanding by notice to the Trustee may waive all past defaults (except with respect to an uncured
nonpayment of principal or interest or failure to deliver the consideration due upon conversion). Upon any such waiver, such default shall cease to exist, and any Event of Default arising therefrom shall be deemed to have been cured, for every
purpose of this Indenture, but no such waiver shall extend to any subsequent or other default or impair any right consequent thereon. 
 Section 7.06. Control by Majority. Except as otherwise set forth in this Indenture or the Notes, the Holders of a majority in principal amount of the outstanding Notes shall have the right to
direct the time, method and place of conducting any proceeding for any remedy available to the Trustee or exercising any trust or power conferred on the Trustee with respect to the Notes; provided that the Trustee may refuse to follow any
direction that conflicts with law or this Indenture, that the Trustee determines may be unduly prejudicial to the rights of another Holder, or that may involve the Trustee in personal liability unless the Trustee is offered indemnity or security
reasonably satisfactory to it against any loss, liability or expense; provided, however, that the Trustee may take any other action deemed proper by the Trustee that is not inconsistent with such direction. 

Section 7.07. Limitations on Suits. Except to enforce the right to receive payment of principal of, or interest on, a Note
when due or to receive the consideration due upon conversion of a Note in accordance with Article 4, a Holder may not pursue any remedy with respect to this Indenture or the Notes unless: 

 

	 	(1)	such Holder has previously given the Trustee notice that an Event of Default is continuing; 

 

	 	(2)	the Holders of at least 25% in principal amount of the Notes then outstanding have requested the Trustee to pursue such remedy; 

 

	 	(3)	such Holders have offered to the Trustee security or indemnity reasonably satisfactory to the Trustee against any loss, liability or expense; 

 

	 	(4)	the Trustee has not complied with such request within 60 days after the receipt of such request and the offer of security or indemnity; and 

 

	 	(5)	the Holders of a majority in principal amount of the Notes then outstanding have not given the Trustee a direction that, in the opinion of the Trustee, is inconsistent
with such request within such 60 day period. 

  
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 A Holder may not use this Indenture to prejudice the rights of another Holder or to obtain a
preference or priority over such other Holder. 
 Section 7.08. Rights of Holders to Receive Payment and to Convert.
Each Holder shall have the right to receive payment or delivery, as the case may be, of (a) the principal (including the Fundamental Change Repurchase Price, if applicable) of, (b) accrued and unpaid interest, if any, on, and
(c) the consideration due upon conversion of, its Notes, on or after the respective due dates expressed or provided for in this Indenture, or to institute suit for the enforcement of any such payment or delivery, as the case may be, and such
right to receive such payment or delivery, as the case may be, on or after such respective dates shall not be impaired or affected without the consent of such Holder. 
 Section 7.09. Collection Suit By Trustee. If an Event of Default in the payment of principal or interest specified in clause (1) or (2) of Section 7.01 occurs and is continuing,
the Trustee may recover judgment in its own name and as trustee of an express trust against the Company or another obligor on the Notes for the whole amount of principal and accrued interest remaining unpaid, together with, to the extent that
payment of such interest is lawful, interest on overdue principal and on overdue installments of interest, in each case at the rate per annum borne by the Notes and such further amount as shall be sufficient to cover the costs and expenses of
collection, including the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel. 

Section 7.10. Trustee May File Proofs of Claim. The Trustee may file such proofs of claim and other papers or documents as
may be necessary or advisable in order to have the claims of the Trustee (including any claim for the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel) and the Holders allowed in any judicial
proceedings relative to the Company (or any other obligor on the Notes), its creditors or its property and shall be entitled and empowered to collect and receive any money or other property payable or deliverable on any such claims and to distribute
the same, and any Custodian in any such judicial proceeding is hereby authorized by each Holder to make such payments to the Trustee and, in the event that the Trustee shall consent to the making of such payments directly to the Holders, to pay to
the Trustee any amount due to it for the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, and any other amounts due the Trustee under Section 8.06, and to the extent that such payment of the
reasonable compensation, expenses, disbursements and advances in any such proceedings shall be denied for any reason, payment of the same shall be secured by a lien on, and shall be paid out of, any and all distributions, dividends, money,
securities and other property which the Holders may be entitled to receive in such proceedings, whether in liquidation or under any plan of reorganization or arrangement or otherwise. Nothing herein contained shall be deemed to authorize the Trustee
to authorize or consent to, or, on behalf of any Holder, to authorize, accept or adopt any plan of reorganization, arrangement, adjustment or composition affecting the Notes or the rights of any Holder thereof, or to authorize the Trustee to vote in
respect of the claim of any Holder in any such proceeding. 
 Section 7.11. Priorities. If the Trustee collects any
money pursuant to this Article 7, it shall pay out the money in the following order: 

  
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 FIRST, to the Trustee for amounts due under Section 8.06; 

SECOND, to Holders for amounts due and unpaid on the Notes for principal (including the Fundamental Change Repurchase Price, if any),
interest and any cash due upon conversion, ratably, without preference or priority of any kind, according to the amounts due and payable on the Notes for principal (including the Fundamental Change Repurchase Price, if any), interest and cash due
upon conversion, respectively; and 
 THIRD, to the Company or such party as a court of competent jurisdiction shall direct.

 The Trustee may fix a record date and payment date for any payment to Holders pursuant to this Section 7.11. 

Section 7.12. Undertaking For Costs. In any suit for the enforcement of any right or remedy under this Indenture or in any
suit against the Trustee for any action taken or omitted by it as Trustee, a court in its discretion may require the filing by any party litigant in the suit of an undertaking to pay the costs of the suit, and the court in its discretion may assess
reasonable costs, including reasonable attorneys’ fees and expenses, against any party litigant in the suit, having due regard to the merits and good faith of the claims or defenses made by the party litigant; provided that this
Section 7.12 does not apply to a suit made by the Trustee, a suit by a Holder pursuant to Section 7.07, a suit by Holders of more than 10% in aggregate principal amount of the Notes then outstanding or a suit by the Holder of any Note for
the enforcement of (x) the obligation of the Company to pay the principal of or accrued and unpaid interest on such Note (including the Fundamental Change Repurchase Price, if applicable) on or after the due date provided for herein or in such
Note or (y) the right to convert such Note in accordance with Article 4. 
 ARTICLE 8 

TRUSTEE 
 Section 8.01. Duties of Trustee. (a) The duties and responsibilities of the Trustee shall be as provided by the TIA. Notwithstanding the foregoing, no provision of this Indenture shall
require the Trustee to expend or risk its own funds or otherwise incur any personal financial liability in the performance of any of its duties hereunder, or in the exercise of any of its rights or powers, if it shall have reasonable grounds for
believing that repayment of such funds or adequate indemnity against such risk or liability is not reasonably assured to it. Whether or not therein expressly so provided, every provision of this Indenture relating to the conduct or affecting the
liability of or affording protection to the Trustee shall be subject to the provisions of this Section. 
 (b) No provision of
this Indenture shall be construed to relieve the Trustee from liability for its own negligent action, its own negligent failure to act or its own willful misconduct, except as expressly provided in Section 8.03. 

(c) In case an Event of Default has occurred that has not been cured or waived, the Trustee shall exercise such of the rights and powers
vested in it by this Indenture, and use the 

  
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same degree of care and skill in their exercise, as a prudent person would exercise or use under the circumstances in the conduct of its own affairs. The Trustee, however, may refuse to follow
any direction that conflicts with law or this Indenture, or that would involve the Trustee in personal liability. Prior to taking any action under this Indenture at the direction of the Holders, the Trustee will be entitled to indemnification
reasonably satisfactory to it against all losses and expenses caused by taking or not taking such action. 

Section 8.02. Notice of Defaults. The Trustee shall give the Holders notice of any default known to the Trustee that has
occurred and is continuing hereunder within 90 days after such default has occurred; provided that, except in the case of a default in the payment of principal of or interest on any Note or a default in the payment or delivery of the
consideration due upon conversion, the Trustee need not deliver such notice if and so long as a committee of trust officers of the Trustee in good faith determines that withholding the notice is in the interests of Holders. In addition, the Trustee
shall give the Holders notice of any default actually known to it as and to the extent provided by the TIA. 

Section 8.03 Certain Rights of Trustee. Subject to Section 8.01(a) and Section 8.01(c): 

(a) the Trustee may rely and shall be protected in acting or refraining from acting upon any resolution, certificate, statement,
instrument, opinion, report, notice, request, direction, consent, order, bond, debenture, note, other evidence of indebtedness or other paper or document believed by it to be genuine and to have been signed or presented by the proper party or
parties; 
 (b) any request or direction of the Company mentioned herein shall be sufficiently evidenced by a Company Order and
any resolution of the Board of Directors may be sufficiently evidenced by a Board Resolution; 
 (c) whenever in the
administration of this Indenture the Trustee shall deem it desirable that a matter be proved or established prior to taking, suffering or omitting any action hereunder, the Trustee (unless other evidence be herein specifically prescribed) may, in
the absence of bad faith on its part, rely upon an Officers’ Certificate; 
 (d) the Trustee may consult with counsel and
the written advice of such counsel or any Opinion of Counsel shall be full and complete authorization and protection in respect of any action taken, suffered or omitted by it hereunder in good faith and in reliance thereon; 

(e) the Trustee shall be under no obligation to exercise any of the rights or powers vested in it by this Indenture at the request or
direction of any of the Holders pursuant to this Indenture, unless such Holders shall have offered to the Trustee security or indemnity reasonably satisfactory to it against any loss, liability or expense which might be incurred by it in compliance
with such request or direction; 
 (f) the Trustee shall not be bound to make any investigation into the facts or matters stated
in any resolution, certificate, statement, instrument, opinion, report, notice, request, direction, consent, order, bond, debenture, note, other evidence of indebtedness or other paper or document, but the Trustee, in its discretion, may make such
further inquiry or investigation into such facts or matters as it may see fit, and, if the Trustee shall determine to make such further 

  
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inquiry or investigation, it shall be entitled to examine the books, records and premises of the Company, personally or by agent or attorney; and 

(g) the Trustee may execute any of the trusts or powers hereunder or perform any duties hereunder either directly or by or through agents
or attorneys and the Trustee shall not be responsible for any misconduct or negligence on the part of any agent or attorney appointed with due care by it hereunder. 
 Section 8.04. Not Responsible for Issuance of Notes. The Trustee makes no representations as to the validity or sufficiency of this Indenture or of the Notes. The Trustee shall not be
accountable for the use or application by the Company of Notes or the proceeds thereof. 
 Section 8.05. May Hold Notes.
The Trustee, any Authenticating Agent, any Paying Agent, any Registrar or any other agent of the Company, in its individual or any other capacity, may become the owner or pledgee of Notes and, subject to Section 8.07 and Section 8.13,
may otherwise deal with the Company with the same rights it would have if it were not Trustee, Authenticating Agent, Paying Agent, Registrar or such other agent. 
 Section 8.06. Compensation and Reimbursement. The Company agrees: 

(a) to pay to the Trustee from time to time reasonable compensation as shall be agreed in writing between the Company and the Trustee for
all services rendered by it hereunder (which compensation shall not be limited by any provision of law in regard to the compensation of a trustee of an express trust); 
 (b) except as otherwise expressly provided herein, to reimburse the Trustee upon its request for all reasonable expenses, disbursements and advances incurred or made by the Trustee in accordance with any
provision of this Indenture (including the reasonable compensation and the expenses and disbursements of its agents and counsel), except any such expense, disbursement or advance as may be attributable to its negligence or bad faith; and 

(c) to indemnify the Trustee for, and to hold it harmless against, any loss, liability or expense incurred without negligence or bad
faith on its part, arising out of or in connection with the acceptance or administration of this trust, including the costs and expenses of defending itself against any claim or liability in connection with the exercise or performance of any of its
powers or duties hereunder. 
 Section 8.07. Disqualification; Conflicting Interests. In the event that the Trustee
acquires any conflicting interest it must eliminate such conflict within 90 days, apply to the SEC for permission to continue as Trustee or resign. Any Agent may do the same with like rights and duties. 

Section 8.08. Corporate Trustee Required; Eligibility. The Trustee shall always satisfy the requirements of paragraphs (1),
(2) and (5) of TIA Section 310(a). The Trustee (or its parent holding company) shall have a combined capital and surplus of at least $50,000,000. If at any time the Trustee shall cease to satisfy any such requirements, it shall resign
immediately in the manner and with the effect specified in this Article 8. The Trustee shall be subject to the 

  
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provisions of TIA Section 310(b). Nothing herein shall prevent the Trustee from filing with the SEC the application referred to in the penultimate paragraph of TIA Section 310(b).

 Section 8.09. Reports by Trustee to Holders. If a report is required by TIA Section 313, within 60 days
after each January 1, beginning with the January 1 following the date of this Indenture, and for so long as Notes remain outstanding, the Trustee shall mail to each Holder a brief report dated as of such January 1 that complies with
TIA Section 313(a) (but if no event described in TIA Section 313(a) has occurred within the twelve months preceding the reporting date, no report need be transmitted). The Trustee also shall comply with TIA Section 313(b) and (c).

 Section 8.10. Resignation and Removal; Appointment of Successor. 

(a) No resignation or removal of the Trustee and no appointment of a successor Trustee pursuant to this Article shall become effective
until the acceptance of appointment by the successor Trustee under Section 8.11. 
 (b) The Trustee may resign at any time
by giving written notice thereof to the Company. If an instrument of acceptance by a successor Trustee shall not have been delivered to the Trustee within 30 days after the giving of such notice of resignation, the resigning Trustee may, at the
expense of the Company, petition any court of competent jurisdiction for the appointment of a successor Trustee. 
 (c) The
Trustee may be removed at any time by act of the Holders of a majority in principal amount of the outstanding Notes, delivered to the Trustee and to the Company. 
 (d) If at any time: 
 (i) the Trustee shall fail to comply with
Section 8.07 after written request therefor by the Company or by any Holder who has been a bona fide Holder of a Note for at least six months, or 
 (ii) the Trustee shall cease to be eligible under Section 8.08 and shall fail to resign after written request therefor by the Company or by any such Holder, or 

(iii) the Trustee shall become incapable of acting or shall be adjudged a bankrupt or insolvent or a receiver of the
Trustee or of its property shall be appointed or any public officer shall take charge or control of the Trustee or of its property or affairs for the purpose of rehabilitation, conservation or liquidation, 

then, in any such case, (A) the Company by a Board Resolution may remove the Trustee, or (B) subject to Section 7.12, any Holder who has
been a bona fide Holder of a Note for at least six months may, on behalf of himself and all others similarly situated, petition any court of competent jurisdiction for the removal of the Trustee and the appointment of a successor Trustee.

 (e) If the Trustee shall resign, be removed or become incapable of acting, or if a vacancy shall occur in the office of
Trustee for any cause, the Company, by a Board Resolution, shall promptly appoint a successor Trustee. If, within one year after such resignation, removal or 

  
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incapability, or the occurrence of such vacancy, a successor Trustee shall be appointed by act of the Holders of a majority in principal amount of the outstanding Notes delivered to the Company
and the retiring Trustee, the successor Trustee so appointed shall, forthwith upon its acceptance of such appointment, become the successor Trustee and supersede the successor Trustee appointed by the Company. If no successor Trustee shall have been
so appointed by the Company or the Holders and accepted appointment in the manner hereinafter provided, any Holder who has been a bona fide Holder of a Note for at least six months may, on behalf of himself and all others similarly situated,
petition any court of competent jurisdiction for the appointment of a successor Trustee. Notwithstanding replacement of the Trustee pursuant to this Section 8.10, the Company’s obligations under Section 8.06 hereof shall continue for
the benefit of the retiring Trustee. 
 (f) The Company shall give notice of each resignation and each removal of the Trustee
and each appointment of a successor Trustee to all Holders in the manner provided in Section 14.02. Each notice shall include the name of the successor Trustee and the address of its Corporate Trust Office. 

Section 8.11. Acceptance of Appointment by Successor. In case of the appointment hereunder of a successor Trustee, such
successor Trustee shall execute, acknowledge and deliver to the Company and to the retiring Trustee an instrument accepting such appointment, and thereupon the resignation or removal of the retiring Trustee shall become effective and such successor
Trustee, without any further act, deed or conveyance, shall become vested with all the rights, powers, trusts and duties of the retiring Trustee; but, on request of the Company or the successor Trustee, such retiring Trustee shall, upon payment of
its charges, execute and deliver an instrument transferring to such successor Trustee all the rights, powers and trusts of the retiring Trustee and shall duly assign, transfer and deliver to such successor Trustee all property and money held by such
retiring Trustee hereunder. Upon the reasonable written request of any such successor Trustee, the Company shall execute any and all instruments for more fully and certainly vesting in and confirming to such successor Trustee all such rights, powers
and trusts. No successor Trustee shall accept its appointment unless at the time of such acceptance such successor Trustee shall be qualified and eligible under this Article. 
 Section 8.12. Merger, Conversion, Consolidation or Succession to Business. Any corporation into which the Trustee may be merged or converted or with which it may be consolidated, or any
corporation resulting from any merger, conversion or consolidation to which the Trustee shall be a party, or any corporation succeeding to all or substantially all the corporate trust business of the Trustee, shall be the successor of the Trustee
hereunder, provided such corporation shall be otherwise qualified and eligible under this Article, without the execution or filing of any paper or any further act on the part of any of the parties hereto. In case any Notes shall have been
authenticated, but not delivered, by the Trustee then in office, any successor by merger, conversion or consolidation to such authenticating Trustee may adopt such authentication and deliver the Notes so authenticated with the same effect as if such
successor Trustee had itself authenticated such Notes. 
 Section 8.13. Preferential Collection of Claims Against
Company. The Trustee shall comply with TIA Section 311(a), excluding any creditor relationship listed in TIA Section 

  
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311(b). A Trustee who has resigned or been removed shall be subject to TIA Section 311(a) to the extent indicated therein. 

Section 8.14. Appointment of Authenticating Agent. (a) The Trustee may appoint an authenticating agent or agents (each,
an “Authenticating Agent”) which shall be authorized to act on behalf of the Trustee to authenticate Notes issued upon original issue and upon exchange, registration of transfer, partial conversion or repurchase or pursuant to
Section 2.03, and Notes so authenticated shall be entitled to the benefits of this Indenture and shall be valid and obligatory for all purposes as if authenticated by the Trustee hereunder. Wherever reference is made in this Indenture to the
authentication and delivery of Notes by the Trustee or the Trustee’s certificate of authentication, such reference shall be deemed to include authentication and delivery on behalf of the Trustee by an Authenticating Agent and a certificate of
authentication executed on behalf of the Trustee by an Authenticating Agent. Each Authenticating Agent shall be acceptable to the Company and shall at all times be a corporation organized and doing business under the laws of the United States of
America, any State thereof or the District of Columbia, authorized under such laws to act as Authenticating Agent, having a combined capital and surplus of not less than $50,000,000 and subject to supervision or examination by Federal or State
authority. If such Authenticating Agent publishes reports of condition at least annually, pursuant to law or to the requirements of said supervising or examining authority, then for the purposes of this Section, the combined capital and surplus of
such Authenticating Agent shall be deemed to be its combined capital and surplus as set forth in its most recent report of condition so published. If at any time an Authenticating Agent shall cease to be eligible in accordance with the provisions of
this Section, such Authenticating Agent shall resign immediately in the manner and with the effect specified in this Section. 

(b) Any corporation into which an Authenticating Agent may be merged or converted or with which it may be consolidated, or any
corporation resulting from any merger, conversion or consolidation to which such Authenticating Agent shall be a party, or any corporation succeeding to all or substantially all the corporate agency or corporate trust business of an Authenticating
Agent, shall continue to be an Authenticating Agent, provided such corporation shall be otherwise eligible under this Section, without the execution or filing of any paper or any further act on the part of the Trustee or the Authenticating Agent.

 (c) An Authenticating Agent may resign at any time by giving written notice thereof to the Trustee and to the Company. The
Trustee may at any time terminate the agency of an Authenticating Agent by giving written notice thereof to such Authenticating Agent and to the Company. Upon receiving such a notice of resignation or upon such a termination, or in case at any time
such Authenticating Agent shall cease to be eligible in accordance with the provisions of this Section, the Trustee may appoint a successor Authenticating Agent which shall be acceptable to the Company and shall deliver written notice of such
appointment by first-class mail, postage prepaid, to all Holders as their names and addresses appear in the register of the Primary Registrar, or by such other means reasonably acceptable to such Holders. Any successor Authenticating Agent upon
acceptance of its appointment hereunder shall become vested with all the rights, powers and duties of its predecessor hereunder, with like effect as if originally named as an Authenticating Agent. No successor Authenticating Agent shall be appointed
unless eligible under the provisions of this Section. 

  
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 (d) The Trustee agrees to pay to each Authenticating Agent from time to time reasonable
compensation for its services under this Section, and the Trustee shall be entitled to be reimbursed for such payments, subject to the provisions of Section 8.06. 
 (e) If an appointment is made pursuant to this Section, the Notes may have endorsed thereon, in addition to the Trustee’s certificate of authentication, an alternative certificate of authentication
in the following form: 
 This is one of the Notes described in the within-mentioned Indenture. 

 

			
	 U.S. Bank National Association,
       as Trustee

		
	By:	 	  

		 	Name:
		 	Title: Authenticating Agent
		
	By:	 	  

		 	Name:
		 	Title: Authorized Officer

 ARTICLE 9 
 SATISFACTION AND DISCHARGE OF INDENTURE 
 Section 9.01. Satisfaction And Discharge Of Indenture. This Indenture shall upon request of the Company contained in an Officers’ Certificate cease to be of further effect, and the
Trustee, at the expense of the Company, shall execute proper instruments acknowledging satisfaction and discharge of all obligations of the Company under this Indenture, when (a) (i) all Notes theretofore authenticated and delivered (other
than Notes that have been destroyed, lost or stolen and which have been replaced or paid as provided in Section 2.07) have been delivered to the Registrar for cancellation; or (ii) the Company has deposited with the Trustee or delivered to
Holders, as applicable, after the Notes have become due and payable, whether at the Maturity Date, on any Fundamental Change Repurchase Date, or otherwise or have been surrendered for conversion, cash or (solely in the case of a conversion) cash
and/or shares of Common Stock sufficient to pay all of the outstanding Notes or satisfy the Company’s Conversion Obligations with respect to converted Notes, as the case may be, and pay all other sums due and payable under this Indenture by the
Company; and (b) the Company has delivered to the Trustee an Officers’ Certificate and an Opinion of Counsel, each stating that all conditions precedent herein provided for relating to the satisfaction and discharge of this Indenture have
been complied with. 
 Notwithstanding the satisfaction and discharge of this Indenture, the obligations of the Company to the
Trustee under Section 8.06 shall survive and, if money or shares of Common Stock shall have been deposited with the Trustee pursuant to clause (a)(ii) of this Section 9.01, the provisions of Section 9.02 and Section 9.04 shall
survive until the Notes have been paid in 

  
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full and the Company’s Conversion Obligations with respect to any converted Notes have been satisfied. 
 Section 9.02. Application of Trust Money and Shares of Common Stock. Subject to the provisions of Section 9.03, the Trustee or Conversion Agent shall hold in trust, for the benefit of the
Holders, all money and shares of Common Stock deposited with it pursuant to Section 9.01 and shall apply the deposited money and shares of Common Stock in accordance with this Indenture and the Notes to the payment or delivery, as the case may
be, of the principal of, and interest on, and the consideration due upon conversion of, the Notes (including the Fundamental Change Repurchase Price, if any); provided that such money and shares of Common Stock need not be segregated from
other funds except to the extent required by law. The Trustee or Conversion Agent shall be under no liability for interest on any money received by it hereunder except as otherwise agreed with the Company. 

Section 9.03. Repayment to Company. The Trustee, each Conversion Agent and each Paying Agent shall promptly pay or deliver to
the Company upon request any excess money or shares of Common Stock (i) deposited with them pursuant to Section 2.05 or Section 9.01 and (ii) held by them at any time. 

The Trustee, each Conversion Agent and each Paying Agent shall pay or deliver to the Company upon request any money or shares of Common
Stock held by them for the payment or delivery, as the case may be, of principal, interest or amounts due upon conversion that remains unclaimed for two years after a right to such money or shares of Common Stock has matured; provided,
however, that the Trustee, such Conversion Agent or such Paying Agent, before being required to make any such payment or delivery, may at the expense of the Company cause to be mailed to each Holder entitled to such money or shares of Common
Stock notice that such money or shares of Common Stock remains unclaimed and that after a date specified therein, which shall be at least 30 days from the date of such mailing, any unclaimed balance of such money or shares of Common Stock then
remaining will be repaid or delivered to the Company. After payment or delivery to the Company, Holders entitled to money or share of Common Stock must look to the Company for payment as general creditors unless an applicable abandoned property law
designates another Person. In the absence of a written request from the Company to return unclaimed funds or shares to the Company, the Trustee, Conversion Agent or Paying Agent shall from time to time deliver all unclaimed funds or shares to or as
directed by applicable escheat authorities, as determined by the Trustee, Conversion Agent or Paying Agent in its sole discretion, in accordance with the customary practices and procedures of the Trustee, Conversion Agent or Paying Agent. Any
unclaimed funds or shares held by the Trustee, Conversion Agent or Paying Agent pursuant to this Section 9.03 shall be held uninvested and without any liability for interest. 

Section 9.04. Reinstatement. If the Trustee, any Conversion Agent or any Paying Agent is unable to apply any money or shares
of Common Stock in accordance with Section 2.05 or Section 9.02 by reason of any legal proceeding or by reason of any order or judgment of any court or governmental authority enjoining, restraining or otherwise prohibiting such
application, then the Company’s obligations under this Indenture and the Notes shall be revived and reinstated as though no deposit had occurred pursuant to Section 2.05 or Section 9.01 until such time as the Trustee, such Conversion
Agent or such Paying Agent is permitted to apply all such 

  
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money or shares of Common Stock in accordance with such Section; provided, however, that if the Company has made any payment or delivery, as the case may be, of the principal of,
interest on, or amounts due upon conversion of, any Notes because of the reinstatement of its obligations, the Company shall be subrogated to the rights of the Holders of such Notes to receive any such payment or delivery from the money or shares of
Common Stock held by the Trustee, such Conversion Agent or such Paying Agent. 
 ARTICLE 10 

AMENDMENTS, SUPPLEMENTS AND WAIVERS 

Section 10.01. Without Consent of Holders. The Company and the Trustee may amend or supplement this Indenture or the Notes
without prior notice to, or the consent of, any Holder to: 
 (a) cure any ambiguity, manifest error, defect or omission or
inconsistency; provided that, in the case of any omission or inconsistency, the rights of Holders are not adversely affected in any material respect; 
 (b) provide for the assumption by a Successor Company of the Company’s obligations under this Indenture pursuant to Article 6; 

(c) add guarantees with respect to the Notes; 
 (d) provide for a successor Trustee in accordance with Section 8.11 or to otherwise comply with any requirement of this Indenture; 

(e) provide for the issuance of additional Notes, to the extent that the Company and the Trustee deem such amendment necessary or
advisable in connection with such issuance; provided that no such amendment or supplement may impair the rights or interests of any Holder of the outstanding Notes; 
 (f) increase the Conversion Rate; 
 (g) secure the Company’s obligations with
respect to the Notes; 
 (h) add to the covenants of the Company for the benefit of the Holders or surrender any right or power
conferred upon the Company; 
 (i) provide for the conversion of Notes in accordance with Article 4; 

(j) make any change that does not adversely affect the rights of any Holder in any material respect; provided that any amendment
to conform the terms of this Indenture or the Notes to the description thereof contained in the preliminary prospectus dated June 21, 2011 related to the offering and sale of the Notes initially issued hereunder, as modified and/or supplemented
by the related pricing term sheet, shall not be deemed to be adverse to any Holder; or 

  
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 (k) comply with any requirement of the SEC in connection with the qualification of this
Indenture under the TIA. 
 Section 10.02. With Consent of Holders. With the consent of the Holders of at least a
majority in principal amount of the Notes then outstanding, including, without limitation, consents obtained in connection with a purchase of, or tender offer or exchange offer for, Notes (i) the Company and the Trustee may amend this Indenture
or the Notes or (ii) compliance in a particular instance by the Company with any provision of this Indenture may be waived; provided that, without the consent of each Holder of an outstanding Note, no amendment, supplement or waiver may:

 (a) reduce the amount of Notes whose Holders must consent to an amendment of this Indenture or the Notes; 

(b) reduce the rate, or extend the stated time for payment, of interest on any Note or reduce the amount, or extend the stated time for
payment, of the Extension Fee; 
 (c) reduce the principal, or extend the Maturity Date, of any Note; 

(d) make any change that adversely affects the right to convert any Note as provided in Article 4; 

(e) reduce the Fundamental Change Repurchase Price of any Note or amend or modify in any manner adverse to Holders the Company’s
obligation to make such payments, whether through an amendment or waiver of provisions in the covenants, definitions or otherwise; 
 (f) change the place or currency of payment of principal or interest or the Extension Fee in respect of any Note; 
 (g) impair the right of any Holder to receive payment of principal of and interest on such Holder’s Notes on or after the due dates therefor or to institute suit for the enforcement of any payment on
or with respect to such Holder’s Notes; 
 (h) adversely affect the ranking of the Notes as the Company’s senior
unsecured indebtedness; or 
 (i) make any change to clauses (a) through (i) of this proviso or Section 7.05.

 It shall not be necessary for the consent of the Holders under this Section 10.02 to approve the particular form of any
proposed amendment, supplement or waiver, but it shall be sufficient if such consent approves the substance thereof. 
 Upon the
request of the Company accompanied by a Board Resolution authorizing the execution of any such amended or supplemental indenture, and upon the filing with the Trustee of evidence satisfactory to the Trustee of the consent of the Holders as
aforesaid, and upon receipt by the Trustee of the documents described in Section 10.06 and Section 14.04, the Trustee shall join with the Company in the execution of such amended or supplemental indenture unless such amended or
supplemental indenture directly affects the Trustee’s own rights, duties 

  
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or immunities under this Indenture or otherwise, in which case the Trustee may in its discretion, but shall not be obligated to, enter into such amended or supplemental indenture. 

After any amendment, supplement or waiver under this Indenture becomes effective, the Company shall mail to the Holders a notice briefly
describing such amendment, supplement or waiver. Any failure of the Company to mail such notice, or any defect therein, shall not, however, in any way impair or affect the validity of any such amendment, supplement or waiver. 

Section 10.03. Compliance With TIA. Every amendment to or supplement of this Indenture or the Notes shall comply with the TIA
as in effect at the date of such amendment or supplement. 
 Section 10.04. Revocation and Effect of Consents. Until
an amendment, supplement or waiver becomes effective, a consent to it by a Holder is a continuing consent by the Holder and every subsequent Holder of a Note or portion of a Note that evidences the same debt as the consenting Holder’s Note,
even if notation of the consent is not made on any Note. However, any such Holder or subsequent Holder may revoke the consent as to its Note or portion of a Note if the Trustee receives the notice of revocation before the date the amendment,
supplement or waiver becomes effective. 
 After an amendment, supplement or waiver entered into pursuant to this Article 10
becomes effective, it shall bind every Holder, this Indenture shall be modified in accordance therewith, and, in the case of a supplemental indenture, such supplemental indenture shall form a part of this Indenture for all purposes, unless such
amendment, supplement or waiver makes a change described in any of clauses (a) through (i) of Section 10.02. In that case the amendment, supplement or waiver shall bind each Holder of a Note who has consented to it and every
subsequent Holder of a Note or portion of a Note that evidences the same debt as the consenting Holder’s Note. 

Section 10.05. Notation on or Exchange of Notes. The Trustee may place an appropriate notation about an amendment, supplement
or waiver on any Note thereafter authenticated. The Company in exchange for all Notes may issue and the Trustee shall, upon receipt of a Company Order, authenticate new Notes that reflect the amendment, supplement or waiver. Failure to make the
appropriate notation or issue a new Note shall not affect the validity and effect of such amendment, supplement or waiver. 

Section 10.06. Trustee to Sign Amendments, Etc. If the Company requests that the Trustee join with the Company in the
execution of any amendment or supplemental indenture hereto, the Trustee shall be provided with and, subject to Section 8.01, shall be fully protected in relying upon in addition to the documents required by Section 14.04, an
Officers’ Certificate and an Opinion of Counsel stating that such amendment or supplemental indenture is authorized or permitted by this Indenture. The Company may not sign an amendment or supplement indenture until the Board of Directors
approves it. 

  
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 ARTICLE 11 
 LISTS OF HOLDERS AND REPORTS BY THE COMPANY AND THE
TRUSTEE 
 Section 11.01. Lists of Holders. The Company covenants and agrees that it will furnish or
cause to be furnished to the Trustee, semi-annually, not more than 15 days after each Regular Record Date in each year beginning with December 15, 2011, and at such other times as the Trustee may request in writing, within 30 days after receipt
by the Company of any such request (or such lesser time as the Trustee may reasonably request in order to enable it to timely provide any notice to be provided by it hereunder), a list in such form as the Trustee may reasonably require of the names
and addresses of the Holders as of a date not more than 15 days (or such other date as the Trustee may reasonably request in order to so provide any such notices) prior to the time such information is furnished, except that no such list need be
furnished so long as the Trustee is acting as Primary Registrar. The Trustee and the Company shall also comply with Section 312(a) of the TIA. 
 Section 11.02. Preservation and Disclosure of Lists. (a) The Trustee shall preserve, in as current a form as is reasonably practicable, the names and addresses of Holders contained in the
most recent list furnished to the Trustee as provided in Section 11.01 and the names and addresses of Holders received by the Trustee in its capacity as Registrar. The Trustee may destroy any list furnished to it as provided in
Section 11.01 upon receipt of a new list so furnished. 
 (b) The rights of Holders to communicate with other Holders with
respect to their rights under this Indenture or under the Notes, and the corresponding rights and duties of the Trustee, shall be as provided by the TIA. 
 (c) Every Holder, by receiving and holding the same, agrees with the Company and the Trustee that neither the Company nor the Trustee nor any agent of either of them shall be held accountable by reason of
any disclosure of information as to names and addresses of Holders made pursuant to the TIA. 
 Section 11.03. Reports
by Trustee. (a) The Trustee shall transmit to Holders such reports concerning the Trustee and its actions under this Indenture as may be required pursuant to the TIA at the times and in the manner provided pursuant thereto. 

(b) A copy of each such report shall, at the time of such transmission to Holders, be filed by the Trustee with each stock exchange upon
which the Notes are listed, with the SEC and with the Company. The Company will notify the Trustee when the Notes are listed on any stock exchange. 
 ARTICLE 12 
 CONCERNING THE HOLDERS

 Section 12.01. Action by Holders. Whenever in this Indenture it is provided that the Holders of a specified
percentage of the aggregate principal amount of the Notes may take any action (including the making of any demand or request, the giving of any notice, consent or 

  
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waiver or the taking of any other action), the fact that at the time of taking any such action, the Holders of such specified percentage have joined therein may be evidenced (a) by any
instrument or any number of instruments of similar tenor executed by Holders in person or by agent or proxy appointed in writing, or (b) by the record of the Holders voting in favor thereof at any meeting of Holders duly called and held in
accordance with the provisions of Article 13, or (c) by a combination of such instrument or instruments and any such record of such a meeting of Holders. 
 Section 12.02. Proof of Execution by Holders. Subject to the provisions of Article 8 and Section 13.05, proof of the execution of any instrument by a Holder or its agent or proxy shall be
sufficient if made in accordance with such reasonable rules and regulations as may be prescribed by the Trustee or in such manner as shall be satisfactory to the Trustee. The holding of Notes shall be proved by the register of the Primary Registrar
or by a certificate of the Primary Registrar. The record of any Holders’ meeting shall be proved in the manner provided in Section 13.06. 
 Section 12.03. Who Are Deemed Absolute Owners. The Company, the Trustee, any Authenticating Agent, any Paying Agent, any Conversion Agent and any Registrar may deem the Person in whose name a
Note shall be registered upon the register of the Primary Registrar to be, and may treat it as, the absolute owner of such Note (whether or not such Note shall be overdue and notwithstanding any notation of ownership or other writing thereon made by
any Person other than the Company or any Registrar) for the purpose of receiving payment of or on account of the principal of and (subject to Section 2.03(c)) accrued and unpaid interest on such Note, for conversion of such Note and for all
other purposes; and neither the Company nor the Trustee nor any Paying Agent nor any Conversion Agent nor any Registrar shall be affected by any notice to the contrary. All such payments or deliveries so made to any Holder for the time being, or
upon its order, shall be valid, and, to the extent of the sums or shares of Common Stock so paid or delivered, effectual to satisfy and discharge the liability for monies payable or shares deliverable upon any such Note. Notwithstanding anything to
the contrary in this Indenture or the Notes following an Event of Default, any holder of a beneficial interest in a Global Note may directly enforce against the Company, without the consent, solicitation, proxy, authorization or any other action of
the Depositary or any other Person, such holder’s right to exchange such beneficial interest for a Certificate Note in accordance with the provisions of this Indenture. 
 ARTICLE 13 
 HOLDERS’ MEETINGS 

Section 13.01. Purpose of Meetings. A meeting of Holders may be called at any time and from time to time pursuant to the
provisions of this Article 13 for any of the following purposes: 
 (a) to give any notice to the Company or to the Trustee or
to give any directions to the Trustee permitted under this Indenture, or to consent to the waiving of any Default or Event of Default hereunder or the rescission of any acceleration, or to take any other action authorized to be taken by Holders
pursuant to any of the provisions of Article 7; 

  
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 (b) to remove the Trustee and nominate a successor trustee pursuant to the provisions of
Article 8; 
 (c) to consent to the execution of an indenture or indentures supplemental hereto pursuant to the provisions of
Section 10.02; or 
 (d) to take any other action authorized to be taken by or on behalf of the Holders of any specified
aggregate principal amount of the Notes under any other provision of this Indenture or under applicable law. 

Section 13.02. Call of Meetings by Trustee. The Trustee may at any time call a meeting of Holders to take any action
specified in Section 13.01, to be held at such time and at such place as the Trustee shall determine. Notice of every meeting of the Holders, setting forth the time and the place of such meeting and in general terms the action proposed to be
taken at such meeting and the establishment of any record date pursuant to Section 14.05, shall be mailed to Holders of such Notes at their addresses as they shall appear on the register of the Primary Registrar. Such notice shall also be
mailed to the Company. Such notices shall be mailed not less than twenty nor more than ninety days prior to the date fixed for the meeting. 
 Any meeting of Holders shall be valid without notice if the Holders of all Notes then outstanding are present in person or by proxy or if notice is waived before or after the meeting by the Holders of all
Notes then outstanding, and if the Company and the Trustee are either present by duly authorized representatives or have, before or after the meeting, waived notice. 
 Section 13.03. Call of Meetings by Company or Holders. In case at any time the Company, pursuant to a Board Resolution, or the Holders of at least 10% of the aggregate principal amount of the
Notes then outstanding, shall have requested the Trustee to call a meeting of Holders, by written request setting forth in reasonable detail the action proposed to be taken at the meeting, and the Trustee shall not have mailed the notice of such
meeting within 20 days after receipt of such request, then the Company or such Holders may determine the time and the place for such meeting and may call such meeting to take any action authorized in Section 13.01, by mailing notice thereof as
provided in Section 13.02. 
 Section 13.04. Qualifications for Voting. To be entitled to vote at any meeting
of Holders a Person shall (a) be a Holder of one or more Notes on the record date pertaining to such meeting or (b) be a Person appointed by an instrument in writing as proxy by a Holder of one or more Notes on the record date pertaining
to such meeting. The only Persons who shall be entitled to be present or to speak at any meeting of Holders shall be the Persons entitled to vote at such meeting and their counsel and any representatives of the Trustee and its counsel and any
representatives of the Company and its counsel. 
 Section 13.05. Regulations. Notwithstanding any other provisions
of this Indenture, the Trustee may make such reasonable regulations as it may deem advisable for any meeting of Holders, in regard to proof of the holding of Notes and of the appointment of proxies, and in regard to the appointment and duties of
inspectors of votes, the submission and examination of proxies, certificates and other evidence of the right to vote, and such other matters concerning the conduct of the meeting as it shall think fit. 

  
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 The Trustee shall, by an instrument in writing, appoint a temporary chairman of the meeting,
unless the meeting shall have been called by the Company or by Holders as provided in Section 13.03, in which case the Company or the Holders calling the meeting, as the case may be, shall in like manner appoint a temporary chairman. A
permanent chairman and a permanent secretary of the meeting shall be elected by vote of the Holders of a majority in principal amount of the Notes represented at the meeting and entitled to vote at the meeting. 

Subject to the provisions of Section 2.09, at any meeting of Holders each Holder or proxyholder shall be entitled to one vote for
each $1,000 principal amount of Notes held or represented by him; provided, however, that no vote shall be cast or counted at any meeting in respect of any Note challenged as not outstanding and ruled by the chairman of the meeting to
be not outstanding. The chairman of the meeting shall have no right to vote other than by virtue of Notes held by it or instruments in writing as aforesaid duly designating it as the proxy to vote on behalf of other Holders. Any meeting of Holders
duly called pursuant to the provisions of Section 13.02 or Section 13.03 may be adjourned from time to time by the Holders of a majority of the aggregate principal amount of Notes represented at the meeting, whether or not constituting a
quorum, and the meeting may be held as so adjourned without further notice. 
 Section 13.06. Voting. The vote upon
any resolution submitted to any meeting of Holders shall be by written ballot on which shall be subscribed the signatures of the Holders or of their representatives by proxy and the outstanding principal amount of the Notes held or represented by
them. The permanent chairman of the meeting shall appoint two inspectors of votes who shall count all votes cast at the meeting for or against any resolution and who shall make and file with the secretary of the meeting their verified written
reports in duplicate of all votes cast at the meeting. A record in duplicate of the proceedings of each meeting of Holders shall be prepared by the secretary of the meeting and there shall be attached to said record the original reports of the
inspectors of votes on any vote by ballot taken thereat and affidavits by one or more Persons having knowledge of the facts setting forth a copy of the notice of the meeting and showing that said notice was mailed as provided in Section 13.02.
The record shall show the principal amount of the Notes voting in favor of or against any resolution. The record shall be signed and verified by the affidavits of the permanent chairman and secretary of the meeting and one of the duplicates shall be
delivered to the Company and the other to the Trustee to be preserved by the Trustee, the latter to have attached thereto the ballots voted at the meeting. 
 Any record so signed and verified shall be conclusive evidence of the matters therein stated. 
 Section 13.07. No Delay of Rights by Meeting. Nothing contained in this Article 13 shall be deemed or construed to authorize or permit, by reason of any call of a meeting of Holders or any
rights expressly or impliedly conferred hereunder to make such call, any hindrance or delay in the exercise of any right or rights conferred upon or reserved to the Trustee or to the Holders under any of the provisions of this Indenture or of the
Notes. 

  
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 ARTICLE 14 
 MISCELLANEOUS 
 Section 14.01. Trust Indenture Act
Controls. If any provision of this Indenture limits, qualifies or conflicts with the duties imposed by TIA Section 318(c), such imposed duties shall control. 
 Section 14.02. Notices. Any request, demand, authorization, direction, notice, consent, waiver or act of Holders or other document provided or permitted by this Indenture to be made upon,
given or furnished to, or filed with, 
 (1) the Trustee by any Holder or by the Company shall be sufficient for every purpose
hereunder if made, given, furnished or filed in writing (or by facsimile transmission to (213) 615-6197 (or such other telephone number specified by the Trustee), provided that oral confirmation of receipt shall have been received) to or
with the Trustee at its Corporate Trust Office, or such other means reasonably acceptable to the Trustee, or 
 (2) the Company
by the Trustee or by any Holder shall be sufficient for every purpose hereunder (unless otherwise herein expressly provided) if in writing and mailed, first-class postage prepaid, to the Company addressed to it at the address of its principal office
specified in the first paragraph of this Indenture or at any other address previously furnished in writing to the Trustee by the Company, Attention: Chief Financial Officer, with a copy to the Secretary or such other means reasonably acceptable to
the Company. 
 Where this Indenture provides for notice to Holders of any event, such notice shall be sufficiently given
(unless otherwise herein expressly provided) if in writing and mailed, first-class postage prepaid, to each Holder affected by such event, at its address as it appears in the register of the Primary Registrar, or by such other means reasonably
acceptable to the Holder, in each case not later than the latest date (if any), and not earlier than the earliest date (if any), prescribed for the giving of such notice. In any case where notice to Holders is given by mail, neither the failure to
mail such notice, nor any defect in any notice so mailed, to any particular Holder shall affect the sufficiency of such notice with respect to other Holders. Where this Indenture provides for notice in any manner, such notice may be waived in
writing by the Person entitled to receive such notice, either before or after the event, and such waiver shall be the equivalent of such notice. Waivers of notice by Holders shall be filed with the Trustee, but such filing shall not be a condition
precedent to the validity of any action taken in reliance upon such waiver. 
 In case by reason of the suspension of regular
mail service or by reason of any other cause it shall be impracticable to give such notice by mail, then such notification as shall be made with the approval of the Trustee shall constitute a sufficient notification for every purpose hereunder.

 Section 14.03. Communications by Holders With Other Holders. Holders may communicate pursuant to TIA
Section 312(b) with other Holders with respect to their rights under this Indenture or the Notes. The Company, the Trustee, each Registrar and any other Person shall have the protection of TIA Section 312(c). 

  
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 Section 14.04. Certificate and Opinion as to Conditions Precedent.  

(a) Upon any request or application by the Company to the Trustee to take any action under this Indenture, the Company shall furnish to
the Trustee at the request of the Trustee: 
 (i) an Officers’ Certificate in form and substance reasonably
satisfactory to the Trustee stating that, in the opinion of the signers, all conditions precedent (including any covenants, compliance with which constitutes a condition precedent), if any, provided for in this Indenture relating to the proposed
action have been complied with; and 
 (ii) an Opinion of Counsel in form and substance reasonably satisfactory
to the Trustee stating that, in the opinion of such counsel, all such conditions precedent (including any covenants, compliance with which constitutes a condition precedent) have been complied with. 

(b) Each Officers’ Certificate and Opinion of Counsel with respect to compliance with a condition or covenant provided for in this
Indenture shall include: 
 (i) a statement that the Person making such certificate or opinion has read such
covenant or condition; 
 (ii) a brief statement as to the nature and scope of the examination or investigation
upon which the statements or opinions contained in such certificate or opinion are based; 
 (iii) a statement
that, in the opinion of such Person, he or she has made such examination or investigation as is necessary to enable him or her to express an informed opinion as to whether or not such covenant or condition has been complied with; and 

(iv) a statement as to whether or not, in the opinion of such Person, such condition or covenant has been complied with;

 provided, however, that with respect to matters of fact an Opinion of Counsel may rely on an Officers’ Certificate or
certificates of public officials. 
 Section 14.05. Record Date for Vote or Consent of Holders. The Company (or, in
the event deposits have been made pursuant to Section 9.01, the Trustee) may set a record date for purposes of determining the identity of Holders entitled to vote or consent to any action by vote or consent authorized or permitted under this
Indenture, which record date shall not be more than 30 days prior to the date of the commencement of solicitation of such action. Notwithstanding the provisions of Section 10.04, if a record date is fixed, those Persons who were Holders of
Notes at the close of business on such record date (or their duly designated proxies), and only those Persons, shall be entitled to take such action by vote or consent or to revoke any vote or consent previously given, whether or not such Persons
continue to be Holders after such record date. 

  
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 Section 14.06. Legal Holidays. If any Interest Payment Date, the Maturity Date
or any Fundamental Change Repurchase Date falls on a day that is not a Business Day, the required payment shall be made on the next succeeding Business Day and no interest on such payment shall accrue in respect of the delay. 

Section 14.07. Governing Law. THIS INDENTURE AND THE NOTES SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE LAWS
OF THE STATE OF NEW YORK. 
 Section 14.08. No Adverse Interpretation of Other Agreements. This Indenture may not be
used to interpret another indenture, loan or debt agreement of the Company or a Subsidiary of the Company. Any such indenture, loan or debt agreement may not be used to interpret this Indenture. 

Section 14.09. No Personal Liability of Directors, Officers, Employees or Stockholders. No past, present or future director,
officer, employee, incorporator or stockholder of the Company, as such, shall have any liability for any obligations of the Company under the Notes, this Indenture or for any claim based on, in respect of, or by reason of, such obligations or their
creation. Each Holder by accepting a Note waives and releases all such liability. The waiver and release are part of the consideration for issuance of the Notes. 
 Section 14.10. Successors. All agreements of the Company in this Indenture and the Notes shall bind its successor. All agreements of the Trustee in this Indenture shall bind its successor.

 Section 14.11. Multiple Counterparts. The parties may sign multiple counterparts of this Indenture. Each signed
counterpart shall be deemed an original, but all of them together represent the same agreement. 
 Section 14.12.
Separability. In case any provisions in this Indenture or in the Notes shall be invalid, illegal or unenforceable, the validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby.

 Section 14.13. Table of Contents, Headings, Etc. The table of contents, cross-reference sheet and headings of the
Articles and Sections of this Indenture have been inserted for convenience of reference only, are not to be considered a part hereof, and shall in no way modify or restrict any of the terms or provisions hereof. 

Section 14.14. Force Majeure. In no event shall the Trustee be responsible or liable for any failure or delay in the
performance of its obligations hereunder arising out of or caused by, directly or indirectly, forces beyond its control, including, without limitation, strikes, work stoppages, accidents, acts of war or terrorism, civil or military disturbances,
nuclear or natural catastrophes or acts of God, and interruptions, loss or malfunctions of utilities, communications or computer (software and hardware) services; provided that the Trustee shall use reasonable efforts consistent with accepted
practices in the banking industry to resume performance as soon as practicable under the circumstances. 

  
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 Section 14.15. Waiver of Jury Trial. EACH OF THE COMPANY AND THE TRUSTEE HEREBY
IRREVOCABLY WAIVES, TO THE FULLEST EXTENT PERMITTED BY APPLICABLE LAW, ANY AND ALL RIGHT TO TRIAL BY JURY IN ANY LEGAL PROCEEDING ARISING OUT OF OR RELATING TO THIS INDENTURE, THE NOTES OR THE TRANSACTIONS CONTEMPLATED HEREBY. 

[SIGNATURE PAGE FOLLOWS] 

  
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 IN WITNESS WHEREOF, the parties hereto have hereunto set their hands as of the date and year
first above written. 
  

			
	NUVASIVE, INC.
		
	By:	 	 /s/ Michael Lambert

		 	Name: Michael Lambert
		 	Title:
	
	 U.S. BANK NATIONAL

      ASSOCIATION, AS TRUSTEE

		
	By:	 	 /s/ Fonda Hall

		 	Name: Fonda Hall
		 	Title: Vice President

  
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 EXHIBIT A 
 [FORM OF FACE OF NOTE] 
 [UNLESS THIS CERTIFICATE IS
PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY TO THE COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER
NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (AND ANY PAYMENT HEREON IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY), ANY
TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL SINCE THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE
HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF A DEPOSITARY OR A NOMINEE THEREOF. THIS SECURITY IS EXCHANGEABLE FOR SECURITIES REGISTERED IN THE NAME OF A PERSON OTHER THAN THE DEPOSITARY OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES
DESCRIBED IN THE INDENTURE AND, UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE
DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE OF THE DEPOSITARY OR BY THE DEPOSITARY OR ANY SUCH NOMINEE TO A SUCCESSOR DEPOSITARY OR A NOMINEE OF SUCH SUCCESSOR DEPOSITARY.]1 

 

	1 	 This bracketed text should be included only if the Note is a Global Note. 

  
 A-1

 NUVASIVE, INC. 

2.75% CONVERTIBLE SENIOR NOTES DUE 2017 
  

			
	No. [    ] 	  	[Initially]2 $         

 CUSIP No.: 670704 AC9 
 NuVasive, Inc., a Delaware corporation (the “Company”, which term shall include any successor corporation under the Indenture referred to on the reverse hereof), promises to pay to
[Cede & Co.]3
[            ], or registered assigns, the principal sum of             DOLLARS
($            ) [or such lesser amount as set forth in the “Schedule of Exchanges of Notes” attached hereto]4 on the Maturity Date, and interest thereon as set forth below. 

This Note shall bear interest at a rate of 2.75% per year from June 28, 2011, or from the most recent date to which interest
had been paid or provided for to, but excluding, the next scheduled Interest Payment Date until the Maturity Date. Interest shall be payable semi-annually in arrears on January 1 and July 1 of each year, beginning on January 1, 2012,
to Holders of record at the close of business on the preceding December 15 and June 15, as the case may be, immediately preceding the relevant Interest Payment Date. The Extension Fee will be payable as set forth in Section 7.04 of
the within-mentioned Indenture. Interest will be computed on the basis of a 360-day year of twelve 30-day months. 
 Any
Defaulted Amounts shall accrue interest per annum at the rate borne by the Notes, subject to the enforceability thereof under applicable law, from, and including, the relevant payment date to, but excluding, the date on which such Defaulted Amounts
shall have been paid by the Company, at its election, in accordance with Section 2.03(d) of the Indenture. 
 [The Company shall pay the principal of and interest on this Note in immediately available funds to the Depositary or its nominee, as the case may be, as the registered Holder of such Note.]5 [As provided in and subject to the provisions of the Indenture, the
Company shall pay the principal of any Notes at the office or agency designated by the Company for that purpose pursuant to Section 2.04 of the Indenture. The Company has initially designated the Trustee as Paying Agent, Registrar, Primary
Registrar, Notes Custodian and Conversion Agent and each of the Corporate Trust Office of the Trustee and the office or agency of the Trustee in the Borough of Manhattan, The City of New York, as an office or agency of the Company for each of the
aforesaid purposes.]6 

 

	2 	 This bracketed text should be included only if the Note is a Global Note. 

	3 	 This bracketed text should be included only if the Note is a Global Note. 

	4 	 This bracketed text should be included only if the Note is a Global Note. 

	5 	 This bracketed text should be included only if the Note is a Global Note. 

	6 	 This bracketed text should be included only if the Note is a Certificated Note. 

  
 A-2

 Reference is made to the further provisions of this Note set forth on the reverse hereof,
including, without limitation, provisions giving the Holder of this Note the right to convert this Note into cash, shares of Common Stock or a combination of cash and shares of Common Stock, as applicable, on the terms and subject to the limitations
set forth in the Indenture. Such further provisions shall for all purposes have the same effect as though fully set forth at this place. 
 This Note shall not be valid or become obligatory for any purpose until the certificate of authentication hereon shall have been manually signed by the Trustee or a duly authorized authenticating agent
under the Indenture. 
 [SIGNATURE PAGE FOLLOWS] 

  
 A-3

 IN WITNESS WHEREOF, the Company has caused this instrument to be duly executed. 

 

			
	NUVASIVE, INC.
		
	By:	 	  

		 	Name:
		 	Title:

 Attest: 
  

			
	By:	 	  

		 	Name:
		 	Title:
		
		 	Dated: [            ], 20[    ]
	
	 TRUSTEE’S CERTIFICATE OF AUTHENTICATION

		
		 	 This is one of the Notes referred to in
 the within-mentioned Indenture.

	
	 U.S. BANK NATIONAL
ASSOCIATION, AS TRUSTEE

		
	By:	 	  

		 	Authorized Signatory

  
 A-4

 [FORM OF REVERSE OF NOTE] 

NUVASIVE, INC. 
 2.75% CONVERTIBLE SENIOR NOTES DUE 2017 
 This Note is one of a duly
authorized issuance of Notes of the Company, designated as its 2.75% Convertible Senior Notes due 2017 (the “Notes”), limited in aggregate principal amount to
$[            ], all issued or to be issued under and pursuant to an Indenture dated as of June 28, 2011 (the “Indenture”), between the Company and U.S. Bank National
Association (the “Trustee”), to which Indenture and all indentures supplemental thereto reference is hereby made for a description of the rights, limitations of rights, obligations, duties and immunities thereunder of the Trustee,
the Company and the Holders of the Notes. Additional Notes may be issued in an unlimited aggregate principal amount, subject to certain conditions specified in the Indenture. 
 In case an Event of Default, as defined in the Indenture, shall have occurred and be continuing, the principal of all Notes may be declared, by either the Trustee or Holders of at least 25% in principal
amount of Notes then outstanding by notice to the Company, and upon said declaration shall become, due and payable, in the manner, with the effect and subject to the conditions and certain exceptions set forth in the Indenture. In case an Event of
Default occurs as a result of certain events of bankruptcy, insolvency or reorganization of the Company, the principal of all Notes then outstanding shall become and be immediately due and payable without any declaration or other act on the part of
the Trustee or any Holder. 
 Subject to the terms and conditions of the Indenture, the Company will make all payments in
respect of the Fundamental Change Repurchase Price and the principal amount on the Maturity Date, as the case may be, to the Holder who surrenders a Note to a Paying Agent to collect such payments in respect of the Note. The Company will pay cash
amounts in money of the United States that at the time of payment is legal tender for payment of public and private debts. 

The Indenture contains provisions permitting the Company and the Trustee in certain circumstances, without the consent of the Holders of
the Notes, and in certain other circumstances, with the consent of the Holders of not less than a majority in aggregate principal amount of the Notes at the time outstanding, evidenced as in the Indenture provided, to execute supplemental indentures
modifying the terms of the Indenture and the Notes as described therein. It is also provided in the Indenture that, subject to certain exceptions, the Holders of a majority in aggregate principal amount of the Notes at the time outstanding may on
behalf of the Holders of all of the Notes waive any past Default or Event of Default under the Indenture and its consequences. 

The Notes are issuable in registered form without coupons in denominations of $1,000 principal amount and integral multiples thereof. At
the office or agency of the Company referred to on the face hereof, and in the manner and subject to the limitations provided in the Indenture, Notes may be exchanged for a like aggregate principal amount of Notes of other authorized denominations,
without payment of any service charge but, if required by the Company or Trustee, with payment of a sum sufficient to cover any transfer or similar tax that may be imposed in connection therewith as a result of the name of the Holder of the new
Notes issued 

  
 A-5

 
upon such exchange of Notes being different from the name of the Holder of the old Notes surrendered for such exchange. 
 The Notes are not subject to redemption through the operation of any sinking fund or otherwise. 
 Upon the occurrence of a Fundamental Change, subject to certain conditions, the Holder has the right, at such Holder’s option, to require the Company to repurchase for cash all of such Holder’s
Notes or any portion thereof (in principal amounts of $1,000 or integral multiples thereof) on the Fundamental Change Repurchase Date at a price equal to the Fundamental Change Repurchase Price. 

Subject to the provisions of the Indenture, the Holder hereof has the right, prior to the close of business on the Business Day
immediately preceding January 1, 2017 only upon the occurrence of certain conditions specified in the Indenture, and on or after January 1, 2017 until the close of business on the second Scheduled Trading Day immediately preceding the
Maturity Date regardless of the occurrence of such conditions, to convert any of its Notes or portion thereof that is $1,000 or an integral multiple thereof. The Company will satisfy such Conversion Obligation in cash or, after receipt by the
Company of the Stockholder Approvals (as defined in the Indenture), the Company may, at its election, satisfy such Conversion Obligation in cash, shares of Common Stock or a combination of cash and shares of Common Stock, as applicable, at the
Conversion Rate specified in the Indenture, as adjusted from time to time as provided in the Indenture. 
 All terms used in
this Note but not specifically defined herein are defined in the Indenture and are used herein as so defined. 
 In the case of
any conflict between the provisions of this Note and the Indenture, the provisions of the Indenture shall control. 
 This Note
shall not be valid until an authorized signatory of the Trustee manually signs the certificate of authentication on this Note. 

THE INDENTURE AND THIS NOTE SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW YORK. 

The Company will furnish to any Holder, upon written request and without charge, a copy of the Indenture. Requests may be made to:
NuVasive, Inc. 7475 Lusk Boulevard, San Diego, California 92121. 

  
 A-6

 ABBREVIATIONS AND DEFINITIONS 

Customary abbreviations may be used in the name of the Holder or an assignee, such as: 

TEN COM (= tenants in common) 
 TEN ENT (= tenants by the entireties) 
 JT TEN (= joint tenants with right of
survivorship and not as tenants in common) 
 CUST (= Custodian) 

UGMA (= Uniform Gifts to Minors Act). 
 Additional abbreviations may also be used though not in the above list. 

  
 A-7

 ASSIGNMENT FORM 

To assign this Note, fill in the form below: 
 I or we assign and transfer this Note to: 
  

 
 (Insert assignee’s social security
or tax I.D. number) 
  
  

 
  

 
  

 
  

 
  
 (Print or type assignee’s name, address and zip code) 
 and irrevocably appoint 

 
  
 agent to transfer this Note on the books of the Company. The agent 
 may substitute another to act
for him or her. 
  

							
	Date:	 		 		 	Your Signature:
				
	  
	 		 		 	  

		 		 		 	 (Sign exactly as your name appears on
 the other side of this Note)

	 		 		 

  

	*	Signature guaranteed by: 

  

			
	 By:
	 	  

  

	*	The signature must be guaranteed by an institution which is a member of one of the following recognized signature guaranty programs: (i) the Securities Transfer
Agent Medallion Program (STAMP); (ii) The New York Stock Exchange Medallion Program (MSP); (iii) the Stock Exchange Medallion Program (SEMP); or (iv) such other guaranty program acceptable to the Trustee. 

  
 A-8

 CONVERSION NOTICE 

To convert this Note into cash, shares of Common Stock or a combination of cash and shares of Common Stock, as applicable, check the box:
 ̈ 
 To convert only part of this Note, state the principal amount to be
converted (which must be $1,000 or a integral multiple of $1,000): $ 
 If you want the stock certificate made out in another
Person’s name, fill in the form below: 
  
  

(Insert assignee’s social security or tax I.D. number) 
  

 
  

 
  

 
  

 
  

 
 (Print or type assignee’s name,
address and zip code) 
  

					
	Date:	 		  	Your Signature:
	  
	 		  	  

		 		  	(Sign exactly as your name appears on the other side of this Note)

  

	*	Signature guaranteed by: 

  

					
	By:	 	  
	 	

  

	*	The signature must be guaranteed by an institution which is a member of one of the following recognized signature guaranty programs: (i) the Securities Transfer
Agent Medallion Program (STAMP); (ii) The New York Stock Exchange Medallion Program (MSP); (iii) the Stock Exchange Medallion Program (SEMP); or (iv) such other guaranty program acceptable to the Trustee. 

  
 A-9

 REPURCHASE NOTICE UPON A FUNDAMENTAL CHANGE 

To: NuVasive, Inc. 
 The undersigned registered owner of this Note hereby irrevocably acknowledges receipt of a notice from NuVasive, Inc. (the “Company”) as to the occurrence of a Fundamental Change with
respect to the Company and requests and instructs the Company to repurchase the entire principal amount of this Note, or the portion thereof (which is $1,000 or an integral multiple thereof) below designated, in accordance with the terms of the
Indenture referred to in this Note at the applicable Fundamental Change Repurchase Price, and to deliver such Fundamental Change Repurchase Price to the registered Holder hereof. 

 

							
				
	Dated:	 	  
	 		 	  

				
	Dated:	 	  
	 		 	  

		 		 		 	Signature(s)
				
		 		 		 	Signature(s) must be guaranteed by a qualified guarantor institution with membership in an approved signature guarantee program pursuant to Rule 17Ad-15 under the Securities
Exchange Act of 1934.
				
		 		 		 	  

		 		 		 	Signature Guaranty

 Principal amount to be repurchased (in an integral multiple of $1,000, if less than all): 

Certificate number of Note to be repurchased: 

NOTICE: The signature to the foregoing election must correspond to the name as written upon the face of the Note in every particular, without alteration
or any change whatsoever. 

  
 A-10

 SCHEDULE OF EXCHANGES OF NOTES7 

The initial principal amount of this Global Note is             
DOLLARS ($[            ]). The following exchanges, repurchases or conversions of a part of this Global Note have been made: 

 

									
	 Date of Exchange,
 Repurchase or
 Conversion
	  	
Amount of Decrease
in Principal Amount
 of this Global Note
	  	
Amount of Increase
in Principal Amount
 of this Global Note
	  	 Principal Amount of

this Global Note

Following Such

Decrease or

Increase
	  	 Signature of

Authorized
Signatory of Notes
 Custodian

	 [            ]
	  	[            ]	  	[            ]	  	[            ]	  	[            ]

  

	7 	 This schedule should be included only if the Note is a Global Note.

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