Document:

EXHIBIT
      4.4

    

    NEITHER
      THIS WARRANT NOR THE SHARES OF COMMON STOCK ISSUABLE UPON EXERCISE HAVE BEEN
      REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), OR UNDER
      ANY STATE SECURITIES LAW. IN ADDITION, SUCH SECURITIES MAY NOT BE SOLD, PLEDGED
      OR OTHERWISE TRANSFERRED UNLESS (i) THERE IS AN EFFECTIVE REGISTRATION STATEMENT
      COVERING THE SECURITIES UNDER THE ACT AND APPLICABLE STATE SECURITIES LAWS,
      (ii) THE COMPANY FIRST RECEIVES AN OPINION FROM AN ATTORNEY, REASONABLY
      ACCEPTABLE TO THE COMPANY, STATING THAT THE PROPOSED TRANSFER IS EXEMPT FROM
      REGISTRATION UNDER THE ACT AND UNDER ALL APPLICABLE STATE SECURITIES LAWS,
      OR
      (iii) THE TRANSFER IS MADE PURSUANT TO RULE 144 PROMULGATED UNDER THE
      ACT.

     

    298,330
      shares of Common Stock

    Dated:
      August 30, 2007

     

    WARRANT
      FOR THE PURCHASE OF

    SHARES
      OF COMMON STOCK

    OF

    TRUE
      NORTH ENERGY CORPORATION

    

    (A
      Nevada
      corporation)

     

    FOR
      VALUE
      RECEIVED, True North Energy Corporation ("Company"), hereby certifies that
      EH&P Investments AG, Albisriederstrasse 164, CH-8040, Zurich, Switzerland or
      his, her or its registered assigns ("Holder"), is entitled, subject to the
      terms
      set forth below, to purchase from the Company, at any time or from time to
      time
      during the three-year period commencing on August 30, 2007 and expiring on
      August 29, 2010, two hundred ninety-eight thousand three hundred thirty
      (298,330) shares of Common Stock of the Company ("Common Stock"), at a purchase
      price of $1.17 per share. The number of shares of Common Stock purchasable
      upon
      exercise of this Warrant, and the purchase price per share, each as adjusted
      from time to time pursuant to the provisions of this Warrant, are hereinafter
      referred to as the "Warrant Shares" and the "Exercise Price,"
      respectively.

     

    1. Exercise

    

    1.1 Procedure
      for Exercise.
      This
      Warrant may be exercised by the Holder, in whole or in part, by the surrender
      of
      this Warrant (with the Notice of Exercise Form attached hereto duly executed
      by
      such Holder) at the principal office of the Company, or at such other office
      or
      agency as the Company may designate, accompanied by payment in full, in lawful
      money of the United States, of an amount equal to the then applicable Exercise
      Price multiplied by the number of Warrant Shares then being purchased upon
      such
      exercise.

     

    1.2 Date
      of
      Exercise.
      Each
      exercise of this Warrant shall be deemed to have been effected immediately
      prior
      to the close of business on the day on which this Warrant shall have been
      surrendered to the Company. At such time, the person or persons in whose name
      or
      names any certificates for Warrant Shares shall be issuable upon such exercise
      shall be deemed to have become the holder or holders of record of the Warrant
      Shares represented by such certificates.

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    1.3 Issuance
      of Certificate. As soon as practicable after the exercise of the purchase
      right represented by this Warrant, the Company at its expense will use its
      best
      efforts to cause to be issued in the name of, and delivered to, the Holder,
      or,
      subject to the terms and conditions hereof, to such other individual or entity
      as such Holder (upon payment by such Holder of any applicable transfer taxes)
      may direct:

     

    (i) a
      certificate or certificates
      for the number of full shares of Warrant Shares to which such Holder shall
      be
      entitled upon such exercise (subject to Section 3 hereof), and

     

    (ii) in
      case such exercise is in
      part only, a new warrant or warrants (dated the date hereof) of like tenor,
      stating on the face or faces thereof the number of shares currently stated
      on
      the face of this Warrant minus the number of such shares purchased by the Holder
      upon such exercise as provided in subsection 1.1 above.

     

    2. Adjustments.

    

    2.1 Split,
      Subdivision or Combination of Shares. If the outstanding shares of the
      Company's Common Stock at any time while this Warrant remains outstanding and
      unexpired shall be subdivided or split into a greater number of shares, or
      a
      dividend in Common Stock shall be paid in respect of Common Stock, the Exercise
      Price in effect immediately prior to such subdivision or at the record date
      of
      such dividend shall, simultaneously with the effectiveness of such subdivision
      or split or immediately after the record date of such dividend (as the case
      may
      be), shall be proportionately decreased. If the outstanding shares of Common
      Stock shall be combined or reverse-split into a smaller number of shares, the
      Exercise Price in effect immediately prior to such combination or reverse split
      shall, simultaneously with the effectiveness of such combination or reverse
      split, be proportionately increased. When any adjustment is required to be
      made
      in the Exercise Price, the number of shares of Warrant Shares purchasable upon
      the exercise of this Warrant shall be changed to the number determined by
      dividing (i) an amount equal to the number of shares issuable upon the exercise
      of this Warrant immediately prior to such adjustment, multiplied by the Exercise
      Price in effect immediately prior to such adjustment, by (ii) the Exercise
      Price
      in effect immediately after such adjustment.

     

    2.2 Reclassification
      Reorganization, Consolidation or Merger. In the case of any reclassification
      of the Common Stock (other than a change in par value or a subdivision or
      combination as provided for in subsection 2.1 above), or any reorganization,
      consolidation or merger of the Company with or into another corporation (other
      than a merger or reorganization with respect to which the Company is the
      continuing corporation and which does not result in any reclassification of
      the
      Common Stock), or a transfer of all or substantially all of the assets of the
      Company, or the payment of a liquidating distribution then, as part of any
      such
      reorganization, reclassification, consolidation, merger, sale or liquidating
      distribution, lawful provision shall be made so that the Holder of this Warrant
      shall have the right thereafter to receive upon the exercise hereof, the kind
      and amount of shares of stock or other securities or property which such Holder
      would have been entitled to receive if, immediately prior to any such
      reorganization, reclassification, consolidation, merger, sale or liquidating
      distribution, as the case may be, such Holder had held the number of shares
      of
      Common Stock which were then purchasable upon the exercise of this Warrant.
      In
      any such case, appropriate adjustment (as reasonably determined by the Board
      of
      Directors of the Company) shall be made in the application of the provisions
      set
      forth herein with respect to the rights and interests thereafter of the Holder
      of this Warrant such that the provisions set forth in this Section 2 (including
      provisions with respect to the Exercise Price) shall thereafter be applicable,
      as nearly as is reasonably practicable, in relation to any shares of stock
      or
      other securities or property thereafter deliverable upon the exercise of this
      Warrant.

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    2.3 Price
      Adjustment. No adjustment in the per share Exercise Price shall be required
      unless such adjustment would require an increase or decrease in the Exercise
      Price of at least $0.01; provided, however, that any adjustments which by reason
      of this paragraph are not required to be made shall be carried forward and
      taken
      into account in any subsequent adjustment. All calculations under this Section
      2
      shall be made to the nearest cent or to the nearest 1/100th of a share, as
      the
      case may be.

     

    2.4 No
      Impairment. The Company will not, by amendment of its Articles of
      Incorporation or through any reorganization, transfer of assets, consolidation,
      merger, dissolution, issue or sale of securities or any other voluntary action,
      avoid or seek to avoid the observance or performance of any of the terms to
      be
      observed or performed hereunder by the Company but will at all times in good
      faith assist in the carrying out of all the provisions of this Section 2 and
      in
      the taking of all such actions as may be necessary or appropriate in order
      to
      protect against impairment of the rights of the Holder of this Warrant to
      adjustments in the Exercise Price.

     

    2.5 Notice
      of Adjustment. Upon any adjustment of the Exercise Price or extension of the
      Warrant exercise period, the Company shall forthwith give written notice thereto
      to the Holder of this Warrant describing the event requiring the adjustment,
      stating the adjusted Exercise Price and the adjusted number of shares
      purchasable upon the exercise hereof resulting from such event, and setting
      forth in reasonable detail the method of calculation and the facts upon which
      such calculation is based.

     

    3. Fractional
      Shares. The Company shall not be required to issue fractions of shares of
      Common Stock upon exercise. If any fractions of a share would, but for this
      Section 3, be issuable upon any exercise, in lieu of such fractional share
      the
      Company shall round up or down to the nearest whole number.

    

    4. Limitation
      on Sales. Each holder of this Warrant acknowledges that this Warrant and the
      Warrant Shares, as of the date of original issuance of this Warrant, have not
      been registered under the Securities Act of 1933, as amended ("Act"), and agrees
      not to sell, pledge, distribute, offer for sale, transfer or otherwise dispose
      of this Warrant or any Warrant Shares issued upon its exercise in the absence
      of
      (a) an effective registration statement under the Act as to this Warrant or
      such
      Warrant Shares or (b) an opinion of counsel, reasonably acceptable to the
      Company, that such registration and qualification are not required. Absent
      prior
      registration, the Warrant Shares issued upon exercise thereof shall be imprinted
      with a legend in substantially the following form:

    

    THE
      SHARES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE
      SECURITIES ACT OF 1933, AS AMENDED, OR UNDER ANY STATE SECURITIES LAWS, AND
      MAY
      NOT BE SOLD, PLEDGED OR OTHERWISE TRANSFERRED UNLESS (i) THERE IS AN EFFECTIVE
      REGISTRATION STATEMENT COVERING THE SHARES UNDER THE ACT AND APPLICABLE STATE
      SECURITIES LAWS, (ii) THE COMPANY FIRST RECEIVES AN OPINION FROM AN
      ATTORNEY, REASONABLY ACCEPTABLE TO THE COMPANY, STATING THAT THE PROPOSED
      TRANSFER IS EXEMPT FROM REGISTRATION UNDER THE ACT AND UNDER ALL APPLICABLE
      STATE SECURITIES LAWS, OR (iii) THE TRANSFER IS MADE PURSUANT TO RULE 144
      PROMULGATED UNDER THE ACT.

    

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    5. Notices
      of Record Date. In case: (i) the Company shall take a record of the holders
      of its Common Stock (or other stock or securities at the time deliverable upon
      the exercise of this Warrant) for the purpose of entitling or enabling them
      to
      receive any dividend or other distribution, or to receive any right to subscribe
      for or purchase any shares of any class or any other securities, or to receive
      any other right, or (ii) of any capital reorganization of the Company, any
      reclassification of the capital stock of the Company, any consolidation or
      merger of the Company with or into another corporation (other than a
      consolidation or merger in which the Company is the surviving entity), or any
      transfer of all or substantially all of the assets of the Company, or (iii)
      of
      the voluntary or involuntary dissolution, liquidation or winding-up of the
      Company, then, and in each such case, the Company will mail or cause to be
      mailed to the Holder of this Warrant a notice specifying, as the case may be,
      (i) the date on which a record is to be taken for the purpose of such dividend,
      distribution or right, and stating the amount and character of such dividend,
      distribution or right, or (ii) the effective date on which such reorganization,
      reclassification, consolidation, merger, transfer, dissolution, liquidation
      or
      winding-up is to take place, and the time, if any is to be fixed, as of which
      the holders of record of Common Stock (or such other stock or securities at
      the
      time deliverable upon the exercise of this Warrant) shall be entitled to
      exchange their shares of Common Stock (or such other stock or securities) for
      securities or other property deliverable upon such reorganization,
      reclassification, consolidation, merger, transfer, dissolution, liquidation
      or
      winding-up. Such notice shall be mailed at least ten (10) days prior to the
      record date or effective date for the event specified in such notice, provided
      that the failure to mail such notice shall not affect the legality or validity
      of any such action.

    

    6. Reservation
      of Stock. The Company will at all times reserve and keep available, solely
      for issuance and delivery upon the exercise of this Warrant, such shares of
      Common Stock and other stock, securities and property, as from time to time
      shall be issuable upon the exercise of this Warrant.

    

    7. Replacement
      of Warrants. Upon receipt of evidence reasonably satisfactory to the Company
      of the loss, theft, destruction or mutilation of this Warrant and (in the case
      of loss, theft or destruction) upon delivery of an indemnity agreement (with
      surety if reasonably required) in an amount reasonably satisfactory to the
      Company, or (in the case of mutilation) upon surrender and cancellation of
      this
      Warrant, the Company will issue, in lieu thereof, a new Warrant of like
      tenor.

    

    8. Transfers,
      etc.

    

    8.1 Warrant
      Register. The Company will maintain a register containing the names and
      addresses of the Holders of this Warrant. Any Holder may change its, his or
      her
      address as shown on the warrant register by written notice to the Company
      requesting such change.

     

    8.2 Holder.
      Until any transfer of this Warrant is made in the warrant register, the Company
      may treat the Holder of this Warrant as the absolute owner hereof for all
      purposes; provided, however, that if and when this Warrant is properly assigned
      in blank, the Company may (but shall not be obligated to) treat the bearer
      hereof as the absolute owner hereof for all purposes, notwithstanding any notice
      to the contrary.

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    9. No
      Rights as Stockholder. Until the exercise of this Warrant, the Holder of
      this Warrant shall not have or exercise any rights by virtue hereof as a
      stockholder of the Company.

    

    10. Successors.
      The rights and obligations of the parties to this Warrant will inure to the
      benefit of and be binding upon the parties hereto and their respective heirs,
      successors, assigns, pledgees, transferees and purchasers. 

    

    11. Change
      or Waiver. Any term of this Warrant may be changed or waived only by an
      instrument in writing signed by the party against which enforcement of the
      change or waiver is sought.

    

    12. Headings.
      The headings in this Warrant are for purposes of reference only and shall not
      limit or otherwise affect the meaning of any provision of this
      Warrant.

    

    13. Governing
      Law. This Warrant shall be governed by and construed in accordance with the
      laws of the State of New York. Each party hereby expressly agrees to the
      jurisdiction of the courts of the State of New York and hereby waives any claim
      or defense of inconvenient forum. 

    

    14. Mailing
      of Notices, etc. All notices and other communications under this Warrant
      (except payment) shall be in writing and shall be sufficiently given if sent
      to
      the Holder or the Company, as the case may be, by hand delivery, private
      overnight courier, with acknowledgment of receipt, or by registered or certified
      mail, return receipt requested, as follows:

    

    
      	 	
              Holder:

            	
              To
                Holder's address on page 1 of this Warrant

              Attention:
                Name of Holder

            

    

     

    
      	 	
              The
                Company:

            	
              To
                the Company's Principal Executive Offices

              Attention:
                President

            

    

     

    or
      to
      such other address as any of them, by notice to the others may designate from
      time to time. Time shall be counted to, or from, as the case may be, the
      delivery in person or by overnight courier or five (5) business days after
      mailing.

     

    
      	 	TRUE
              NORTH ENERGY CORPORATION
	 	 
	 	
              By:

            	     /s/
              John Folnovic
	 	Name:
              John Folnovic
	 	 	     Title:
              President

    

    
       

    

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    NOTICE
      OF EXERCISE

     

    TO: True
      North
      Energy Corporation 

    

    1.
      The
      undersigned hereby elects to purchase ________ shares of the True North Energy
      Corporation, pursuant to terms of the attached Warrant, and tenders herewith
      payment of the Exercise Price of such shares in full, together with all
      applicable transfer taxes, if any.

     

    2.
      Please
      issue a certificate or certificates representing said shares of the Common
      Stock
      in the name of the undersigned or in such other name as is specified
      below:

     

    3.
      The
      undersigned represents that it will sell the shares of Common Stock pursuant
      to
      an effective Registration Statement under the Securities Act of 1933, as
      amended, or an exemption from registration thereunder.

     

    
      	 	 
	 	
              (Name)

            
	 	 
	 	
              (Address)

            
	 	 
	 	 
	 	 
	 	 
	 	 
	 	
              (Taxpayer
                Identification Number)

            

    

     

    
      	 	 	 
	(Print
              Name of Holder)	 
	 	 
	 By:	 	 
	 	 	 
	 Title:	 	 
	 	 	 
	 Date:Unassociated Document

    
      Exhibit
        10.52

    

     

    SUNESIS
      PHARMACEUTICALS, INC. 

    2005
      EQUITY INCENTIVE AWARD PLAN

     

    STOCK
      OPTION GRANT NOTICE AND STOCK OPTION AGREEMENT

    

    Sunesis
      Pharmaceuticals, Inc. (the “Company”),
      pursuant to the Sunesis Pharmaceuticals, Inc. 2005 Equity Incentive Award Plan
      (the “Plan”)
      hereby
      grants to the Optionee listed below (“Optionee”),
      an
      option to purchase the number of shares of the Company’s Stock set forth below
      (the “Option”).
      This
      Option is subject to all of the terms and conditions as set forth herein and
      in
      the Stock Option Agreement and the Plan, each of which are attached hereto
      and
      incorporated herein by reference. Capitalized terms not specifically defined
      herein shall have the meanings specified in the Plan.

     

    
      	
              Optionee:

            	 
	
              Date
                of Stock Option Agreement:

            	 
	
              Grant
                Date:

            	 
	
              Vesting
                Commencement Date: 

            	 
	
              Exercise
                Price per Share:

            	
              $
                _____ per share

            
	
              Total
                Number of Shares Granted:

            	 
	
              Total
                Exercise Price:

            	
              $

            
	
              Expiration
                Date:

            	 

    

    

    Type
      of Option:    

    

    
      	Vesting
              Schedule:	
              [1/48th
                of
                the shares subject to the Option shall vest monthly over four years
                commencing on _______________, such that 100% of the shares subject
                to the
                option will be fully vested on _______________, subject to the Optionee’s
                continued service with the
                Company.]

            

    

     

    By
      his or
      her signature and the Company’s signature below, Optionee agrees to be bound by
      the terms and conditions of the Plan and the Stock Option Agreement attached
      hereto. Optionee has reviewed the Stock Option Agreement and the Plan in their
      entirety, has had an opportunity to obtain the advice of counsel prior to
      executing this Option and fully understands all provisions of the Grant Notice,
      the Stock Option Agreement and the Plan. Optionee hereby agrees to accept as
      binding, conclusive and final all decisions or interpretations of the Committee
      upon any questions arising under the Plan or this Option. Optionee further
      agrees to notify the Company upon any change in the residence address indicated
      below.

     

    
      	
              SUNESIS
                PHARMACEUTICALS, INC. 

            	
              OPTIONEE:

            
	
              By:
                      

            	
              By:
                      

            
	
              Print
                Name: 

            	
              Print
                Name: 

            
	
              Title:
                  

            	 
	
              Address:   341
                Oyster
                Point Blvd.

              South
                San Francisco, CA 94080

            	
              Address: 

            

    

    

    
      
        
        

      

      
        
          GRANT
            NOTICE PAGE 1

        

        
          

        

      

      
        
        

      

    

     

     

    SUNESIS
      PHARMACEUTICALS, INC.

    2005
      EQUITY INCENTIVE AWARD PLAN

     

    STOCK
      OPTION AGREEMENT

     

    Pursuant
      to the Stock Option Grant Notice (“Grant
      Notice”)
      to
      which this Stock Option Agreement (this “Agreement”)
      is
      attached, Sunesis Pharmaceuticals, Inc. (the “Company”)
      has
      granted to the Optionee set forth in the Grant Notice (the “Optionee”)
      the
      Option under the Sunesis Pharmaceuticals, Inc. 2005 Equity Incentive Award
      Plan
      (the “Plan”)
      to
      purchase the number of shares of Stock indicated in the Grant Notice at the
      exercise price indicated in the Grant Notice (the “Option”).
      The
      Option is subject to all of the terms and conditions set forth herein and in
      the
      Grant Notice and the Plan. 

     

    ARTICLE
      I

    DEFINITIONS;
      INCORPORATION OF TERMS

     

    1.1 Definitions.
      Capitalized terms not specifically defined herein shall have the meanings
      specified in the Plan.

     

    1.2 Incorporation
      of Terms of Plan.
      The
      Option is subject to the terms and conditions of the Plan which are incorporated
      herein by reference.

     

    ARTICLE
      II

    GRANT
      OF OPTION

     

    2.1 Grant
      of Option.
      In
      consideration of the Optionee’s service with the Company or its Subsidiaries and
      for other good and valuable consideration, effective as of the Grant Date set
      forth in the Grant Notice (the “Grant
      Date”),
      the
      Company irrevocably grants to the Optionee the Option to purchase any part
      or
      all of an aggregate of the number of shares of Stock set forth in the Grant
      Notice, upon the terms and conditions set forth in this Agreement. Unless
      designated as a Non-Qualified Stock Option in the Grant Notice, the Option
      shall
      be an Incentive Stock Option to the maximum extent permitted by
      law.

     

    2.2 Purchase
      Price.
      The
      exercise price per share of the Stock subject to the Option per share shall
      be
      as set forth in the Grant Notice, without commission or other charge;
provided,
      however,
      that if
      this Option is designated as an Incentive Stock Option, the exercise price
      per
      share of the shares subject to the Option shall not be less than the greater
      of
      (i) 100% of the Fair Market Value of a share of Stock on the Grant Date, or
      (ii) 110% of the Fair Market Value of a share of Stock on the Grant Date in
      the case of an Optionee then owning (within the meaning of Section 424(d)
      of the Code) more than 10% of the total combined voting power of all classes
      of
      stock of the Company or any Subsidiary or parent corporation thereof (within
      the
      meaning of Section 422 of the Code); provided,
      further,
      that in
      no event shall such exercise price be less 100% of the Fair Market Value of
      a
      share of Stock on the Grant Date or than the par value of a share of Stock,
      unless otherwise permitted by applicable law.

     

    2.3 Consideration
      to the Company.
      In
      consideration of the granting of the Option by the Company, the Optionee agrees
      to render faithful and efficient services to the Company or any Subsidiary,
      with
      such duties and responsibilities as the Company shall from time to time
      prescribe. Nothing in the Plan or this Agreement shall confer upon the Optionee
      any right to (a) continue in the employ of the Company or any Subsidiary or
      shall interfere with or restrict in any way the rights of the Company and its
      Subsidiaries, which are hereby expressly reserved, to discharge the Optionee,
      if
      the Optionee is an Employee, or (b) continue to provide services to the Company
      or any Subsidiary or shall interfere with or restrict in any way the rights
      of
      the Company or its Subsidiaries, which are hereby expressly reserved, to
      terminate the services of Optionee, if the Optionee is a consultant to the
      Company, at any time for any reason whatsoever, with or without cause, except
      to
      the extent expressly provided otherwise in a written agreement between the
      Company and the Optionee.

     

    
      
        
        

      

      
        
          STOCK
            OPTION AGREEMENT PAGE 1

        

        
          

        

      

      
        
        

      

    

     

     

    ARTICLE
      III

    PERIOD
      OF EXERCISABILITY

     

    3.1 Commencement
      of Exercisability.

     

    (a) Subject
      to Sections 3.3 and 5.9, the Option shall become exercisable upon becoming
      vested in such amounts and at such times as are set forth in the Grant
      Notice.

     

    (b) No
      portion of the Option which has not become vested and exercisable at Termination
      of Service (as defined in Section 3.3 below) shall thereafter become
      exercisable, except as may be otherwise provided by the Committee or as set
      forth in a written agreement between the Company and the Optionee.

     

    3.2 Duration
      of Exercisability.
      The
      installments provided for in Section 3.1(a) are cumulative. Each such
      installment which becomes vested and exercisable pursuant to Section 3.1
      shall remain exercisable until it becomes unexercisable under
      Section 3.3.

     

    3.3 Expiration
      of Option.
      The
      Option may not be exercised to any extent by anyone after the first to occur
      of
      the following events:

     

    (a) The
      expiration of ten years from the Grant Date; or

     

    (b) If
      this
      Option is designated as an Incentive Stock Option and the Optionee owned (within
      the meaning of Section 424(d) of the Code), at the time the Option was
      granted, more than 10% of the total combined voting power of all classes of
      stock of the Company or any Subsidiary or parent corporation thereof (within
      the
      meaning of Section 422 of the Code), the expiration of five years from the
      date
      the Option was granted; or

     

    (c) The
      expiration of three months following the date of the Optionee’s Termination of
      Service, unless such Termination of Service occurs by reason of the Optionee’s
      death or Disability or unless a different period is set forth in a written
      agreement between the Optionee and the Company, as approved by the Committee;
      or

     

    (d) The
      expiration of twelve months following
      the date of the Optionee’s Termination of Service by reason of the Optionee’s
      death or Disability. 

     

    (e) For
      purposes of this Agreement, “Termination
      of Service”
means
      the time when the service relationship (whether as an Employee or a consultant)
      between the Optionee and the Company or any Subsidiary is terminated for any
      reason, with or without cause, including, but not by way of limitation, a
      termination by resignation, discharge, death or Disability; but excluding a
      termination where there is a simultaneous reemployment or continuing employment
      or consultancy of the Optionee by the Company or any Subsidiary or a parent
      corporation thereof (within the meaning of Section 422 of the Code). The
      Committee, in its absolute discretion, shall determine the effect of all matters
      and questions relating to Termination of Service for the purposes of this
      Agreement, and all questions of whether particular leaves of absence for
      Optionees who are Employees of the Company or any of its Subsidiaries constitute
      Terminations of Service; provided,
      however,
      that,
      if this Option is designated as an Incentive Stock Option, unless otherwise
      determined by the Committee in its discretion, a leave of absence, change in
      status from an Employee to an independent contractor or other change in the
      employee-employer relationship shall constitute a Termination of Service if,
      and
      to the extent that, such leave of absence, change in status or other change
      interrupts employment for the purposes of Section 422(a)(2) of the Code and
      the
      then applicable regulations and revenue rulings under said Section.
      Notwithstanding any other provision of the Plan or this Agreement, the Company
      or any Subsidiary has an absolute and unrestricted right to terminate the
      Optionee’s employment and/or consultancy at any time for any reason whatsoever,
      with or without cause, except to the extent expressly provided otherwise in
      a
      written agreement between the Company and the Optionee.

     

    
      
        
        

      

      
        
          STOCK
            OPTION AGREEMENT PAGE 2

        

        
          

        

      

      
        
        

      

    

     

     

    3.4 Special
      Tax Consequences.
      The
      Optionee acknowledges that, to the extent that the aggregate Fair Market Value
      of stock with respect to which Incentive Stock Options (but without regard
      to
      Section 422(d) of the Code), including the Option, are exercisable for the
      first time by the Optionee during any calendar year (under the Plan and all
      other incentive stock option plans of the Company, any Subsidiary and any parent
      corporation thereof (within the meaning of Section 422 of the Code)) exceeds
      $100,000, the Option and such other options shall be treated as not qualifying
      under Section 422 of the Code but rather shall be treated as Non-Qualified
      Stock Options. The Optionee further acknowledges that the rule set forth in
      the
      preceding sentence shall be applied by taking options into account in the order
      in which they were granted. For purposes of these rules, the Fair Market Value
      of Stock shall be determined as of the time the option with respect to such
      Stock is granted.

     

    ARTICLE
      IV

    EXERCISE
      OF OPTION

     

    4.1 Person
      Eligible to Exercise.
      Except
      as provided in Sections 5.2(b) and 5.2(c), during the lifetime of the Optionee,
      only the Optionee may exercise the Option or any portion thereof. 

     

    4.2 Partial
      Exercise.
      Any
      vested and exercisable portion of the Option or the entire Option, if then
      wholly vested and exercisable, may be exercised in whole or in part at any
      time
      prior to the time when the Option or portion thereof becomes unexercisable
      under
      Section 3.3.

     

    4.3 Manner
      of Exercise.
      The
      Option, or any exercisable portion thereof, may be exercised solely by delivery
      to the Secretary of the Company or the Secretary’s office of all of the
      following prior to the time when the Option or such portion thereof becomes
      unexercisable under Section 3.3:

     

    (a) An
      Exercise Notice in writing signed by the Optionee or the other person then
      entitled to exercise the Option or portion thereof, stating that the Option
      or
      portion thereof is thereby exercised, such notice complying with all applicable
      rules established by the Committee. Such notice shall be substantially in the
      form attached as Exhibit
      A
      (or such
      other form as is prescribed by the Committee); and

     

    (b)   (i) Full
      payment (in cash or by check) for the shares with respect to which the Option
      or
      portion thereof is exercised, to the extent permitted under applicable laws;
      or

     

    (ii) To
      the
      extent permitted under applicable laws, through the delivery of a notice that
      the Optionee has placed a market sell order with a broker with respect to shares
      of Stock then issuable upon exercise of the Option, and that the broker has
      been
      directed to pay a sufficient portion of the net proceeds of the sale to the
      Company in satisfaction of the Option exercise price, provided,
      that
      payment of such proceeds is made to the Company upon settlement of such sale;
      or

     

    (iii) With
      the
      consent of the Committee, any combination of the consideration provided in
      the
      foregoing subparagraphs (i) and (ii); and

     

    
      
        
        

      

      
        
          STOCK
            OPTION AGREEMENT PAGE 3

        

        
          

        

      

      
        
        

      

    

     

     

    (c) A
      bona
      fide written representation and agreement, in such form as is prescribed by
      the
      Committee, signed by the Optionee or other person then entitled to exercise
      such
      Option or portion thereof, stating that the shares of Stock are being acquired
      for the Optionee’s own account, for investment and without any present intention
      of distributing or reselling said shares or any of them except as may be
      permitted under the Securities Act of 1933, as amended (the “Securities
      Act”) and
      then
      applicable rules and regulations thereunder, and that the Optionee or other
      person then entitled to exercise such Option or portion thereof will indemnify
      the Company against and hold it free and harmless from any loss, damage, expense
      or liability resulting to the Company if any sale or distribution of the shares
      by such person is contrary to the representation and agreement referred to
      above.  The Committee may, in its absolute discretion, take whatever
      additional actions it deems appropriate to ensure the observance and performance
      of such representation and agreement and to effect compliance with the
      Securities Act and any other federal or state securities laws or regulations.
      Without limiting the generality of the foregoing, the Committee may require
      an
      opinion of counsel acceptable to it to the effect that any subsequent transfer
      of shares acquired on an Option exercise does not violate the Securities Act,
      and may issue stop-transfer orders covering such shares. Share certificates
      evidencing Stock issued on exercise of the Option shall bear an appropriate
      legend referring to the provisions of this subsection (c) and the
      agreements herein. The written representation and agreement referred to in
      the
      first sentence of this subsection (c) shall, however, not be required if
      the shares to be issued pursuant to such exercise have been registered under
      the
      Securities Act, and such registration is then effective in respect of such
      shares; and

     

    (d) Full
      payment to the Company (or other employer corporation) of all amounts which,
      under federal, state, local or foreign tax law, it is required to withhold
      upon
      exercise of the Option. With the consent of the Committee, shares of Stock
      issuable to the Optionee upon exercise of the Option, having a Fair Market
      Value
      at the date of Option exercise equal to the statutory minimum sums required
      to
      be withheld, may be used to make all or part of such payment; and

    

    (e) In
      the
      event the Option or portion thereof shall be exercised pursuant to
      Section 4.1 by any person or persons other than the Optionee, appropriate
      proof of the right of such person or persons to exercise the
      Option.

     

    4.4 Conditions
      to Issuance of Stock Certificates.
      The
      shares of Stock deliverable upon the exercise of the Option, or any portion
      thereof, shall be fully paid and nonassessable. The Company shall not be
      required to issue or deliver any certificate or certificates for shares of
      Stock
      purchased upon the exercise of the Option or portion thereof prior to
      fulfillment of all of the following conditions:

     

    (a) The
      admission of such shares to listing on all stock exchanges on which such Stock
      is then listed; and

     

    (b) The
      completion of any registration or other qualification of such shares under
      any
      state or federal law or under rulings or regulations of the Securities and
      Exchange Commission or of any other governmental regulatory body, which the
      Committee shall, in its absolute discretion, deem necessary or advisable;
      and

     

    (c) The
      obtaining of any approval or other clearance from any state or federal
      governmental agency which the Committee shall, in its absolute discretion,
      determine to be necessary or advisable; and

     

    (d) The
      receipt by the Company of full payment for such shares, including payment of
      all
      amounts which, under federal, state or local tax law, the Company (or other
      employer corporation) is required to withhold upon exercise of the Option;
      and

     

    
      
        
        

      

      
        
          STOCK
            OPTION AGREEMENT PAGE 4

        

        
          

        

      

      
        
        

      

    

     

     

    (e) The
      lapse
      of such reasonable period of time following the exercise of the Option as the
      Committee may from time to time establish for reasons of administrative
      convenience.

     

    4.5 Rights
      as Stockholder.
      The
      holder of the Option shall not be, nor have any of the rights or privileges
      of,
      a stockholder of the Company in respect of any shares purchasable upon the
      exercise of any part of the Option unless and until such shares of Stock have
      been issued (as evidenced by the appropriate entry on the books of the Company
      or of a duly authorized transfer agent of the Company.)

     

    ARTICLE
      V

    OTHER
      PROVISIONS

     

    5.1 Administration.
      The
      Committee shall have the power to interpret the Plan and this Agreement and
      to
      adopt such rules for the administration, interpretation and application of
      the
      Plan as are consistent therewith and to interpret, amend or revoke any such
      rules. All actions taken and all interpretations and determinations made by
      the
      Committee in good faith shall be final and binding upon the Optionee, the
      Company and all other interested persons. No member of the Committee shall
      be
      personally liable for any action, determination or interpretation made in good
      faith with respect to the Plan, this Agreement or the Option. In its absolute
      discretion, the Board may at any time and from time to time exercise any and
      all
      rights and duties of the Committee under the Plan and this
      Agreement.

     

    5.2 Option
      Not Transferable.

     

    (a) Subject
      to Section 5.2(b), the Option may not be sold, pledged, assigned or transferred
      in any manner other than by will or the laws of descent and distribution unless
      and until the Option has been exercised, or the shares underlying such Option
      have been issued, and all restrictions applicable to such shares have lapsed.
      Neither the Option nor any interest or right therein shall be liable for the
      debts, contracts or engagements of the Optionee or his or her successors in
      interest or shall be subject to disposition by transfer, alienation,
      anticipation, pledge, encumbrance, assignment or any other means whether such
      disposition be voluntary or involuntary or by operation of law by judgment,
      levy, attachment, garnishment or any other legal or equitable proceedings
      (including bankruptcy), and any attempted disposition thereof shall be null
      and
      void and of no effect, except to the extent that such disposition is permitted
      by the preceding sentence.

     

    (b) Notwithstanding
      any other provision in this Agreement, with the consent of the Committee and
      to
      the extent the Option is not intended to qualify as an Incentive Stock Option,
      the Option may be transferred to, exercised by and paid to certain persons
      or
      entities related to the Optionee, including but not limited to members of the
      Optionee’s family, charitable institutes or trusts or other entities whose
      beneficiaries or beneficial owners are members of the Optionee’s family or to
      such other persons or entities as may be expressly approved by the Committee
      (each a “Permitted
      Transferee”),
      pursuant to such conditions and procedures as the Committee may
      require.

     

    (c) Unless
      transferred to a Permitted Transferee in accordance with Section 5.2(b), during
      the lifetime of the Optionee, only the Optionee may exercise the Option or
      any
      portion thereof. Subject to such conditions and procedures as the Committee
      may
      require, a Permitted Transferee may exercise the Option or any portion thereof
      in accordance with this Agreement. After the death of the Optionee, any
      exercisable portion of the Option may, prior to the time when the Option becomes
      unexercisable under Section 3.3, be exercised by the Permitted Transferee
      or the Optionee’s beneficiary designated in accordance with Section 10.4 of the
      Plan, as applicable. If no beneficiary has been designated or survives the
      Optionee, the Option may be exercised by the person entitled to such exercise
      pursuant to the Optionee’s will or the laws of descent and
      distribution.

     

    
      
        
        

      

      
        
          STOCK
            OPTION AGREEMENT PAGE 5

        

        
          

        

      

      
        
        

      

    

     

     

    5.3 Restrictive
      Legends and Stop-Transfer Orders.

     

    (a) The
      share
      certificate or certificates evidencing the shares of Stock purchased hereunder
      shall be endorsed with any legends that may be required by state or federal
      securities laws.

     

    (b) The
      Optionee agrees that, in order to ensure compliance with the restrictions
      referred to herein, the Company may issue appropriate “stop transfer”
instructions to its transfer agent, if any, and that, if the Company transfers
      its own securities, it may make appropriate notations to the same effect in
      its
      own records.

     

    (c) The
      Company shall not be required: (i) to transfer on its books any shares of Stock
      that have been sold or otherwise transferred in violation of any of the
      provisions of this Agreement, or (ii) to treat as owner of such shares of Stock
      or to accord the right to vote or pay dividends to any purchaser or other
      transferee to whom such shares shall have been so transferred.

     

    5.4 Shares
      to Be Reserved.
      The
      Company shall at all times during the term of the Option reserve and keep
      available such number of shares of Stock as will be sufficient to satisfy the
      requirements of this Agreement.

     

    5.5 Notices.
      Any
      notice to be given under the terms of this Agreement to the Company shall be
      addressed to the Company in care of the Secretary, and any notice to be given
      to
      the Optionee shall be addressed to the Optionee at the address given beneath
      the
      Optionee’s signature on the Grant Notice. By a notice given pursuant to this
      Section 5.5, either party may hereafter designate a different address for
      notices to be given to that party. Any notice which is required to be given
      to
      the Optionee shall, if the Optionee is then deceased, be given to the Optionee’s
      designated beneficiary if any, or the person otherwise entitled to exercise
      his
      or her Option pursuant to Section 4.1 by written notice under this
      Section 5.6.  Any notice shall be deemed duly given when sent via
      email or enclosed in a properly sealed envelope or wrapper addressed as
      aforesaid and deposited (with postage prepaid) in a post office or branch post
      office regularly maintained by the United States Postal Service.

     

    5.6 Titles.
      Titles
      are provided herein for convenience only and are not to serve as a basis for
      interpretation or construction of this Agreement.

     

    5.7 Notification
      of Disposition.
      If this
      Option is designated as an Incentive Stock Option, the Optionee shall give
      prompt notice to the Company of any disposition or other transfer of any shares
      of stock acquired under this Agreement if such disposition or transfer is made
      (a) within two years from the Grant Date with respect to such shares or (b)
      within one year after the transfer of such shares to him. Such notice shall
      specify the date of such disposition or other transfer and the amount realized,
      in cash, other property, assumption of indebtedness or other consideration,
      by
      the Optionee in such disposition or other transfer.

     

    5.8 Construction.
      This
      Agreement shall be administered, interpreted and enforced under the laws of
      the
      State of Delaware without regard to conflicts of laws thereof.

     

    5.9 Conformity
      to Securities Laws.
      The
      Optionee acknowledges that the Plan is intended to conform to the extent
      necessary with all provisions of the Securities Act and the Exchange Act and
      any
      and all regulations and rules promulgated by the Securities and Exchange
      Commission thereunder, and all applicable foreign and state securities laws
      and
      regulations. Notwithstanding anything herein to the contrary, the Plan shall
      be
      administered, and the Option is granted and may be exercised, only in such
      a
      manner as to conform to such laws, rules and regulations. To the extent
      permitted by applicable law, the Plan and this Agreement shall be deemed amended
      to the extent necessary to conform to such laws, rules and
      regulations.

     

    5.10 Amendments.
      This
      Agreement may not be modified, amended or terminated except by an instrument
      in
      writing, signed by the Optionee or such other person as may be permitted to
      exercise the Option pursuant to Section 4.1 and by a duly authorized
      representative of the Company.

     

    
      
        
        

      

      
        
          STOCK
            OPTION AGREEMENT PAGE 6

        

        
          

        

      

      
        
        

      

    

    EXHIBIT
      A 

     

    TO
      GRANT NOTICE AND STOCK OPTION AGREEMENT

     

    FORM
      OF EXERCISE NOTICE

     

    

    Effective
      as of today, ___________, _____, the undersigned (“Optionee”)
      hereby
      elects to exercise Optionee’s option to purchase _________ shares of common
      stock (the “Shares”)
      of
      Sunesis Pharmaceuticals, Inc. (the “Company”)
      under
      and pursuant to the Sunesis Pharmaceuticals, Inc. 2005 Equity Incentive
      Award
      Plan
      (the
“Plan”)
      and
      the Grant Notice and Stock Option Agreement dated _____________, _____, (the
      “Option
      Agreement”).
      Capitalized terms used herein without definition shall have the meanings given
      in the Option Agreement.

     

    
      	
              Grant
                Date:

            	 
	
              Number
                of Shares as to which Option is Exercised:

            	 
	
              Exercise
                Price per Share:

            	
              $____________

            
	
              Total
                Exercise Price:

            	
              $____________

            
	
              Certificate
                to be issued in name of:

            	 
	
              Cash
                Payment delivered herewith: 

            	
              $____________
                (Representing the full Exercise Price for the Shares, as well as
                any
                applicable withholding tax)

            

    

    

    Type
      of Option:   
      Incentive Stock Option Non-Qualified Stock Option

    

    1. Representations
      of Optionee.
      Optionee acknowledges that Optionee has received, read and understood the Plan
      and the Option Agreement. Optionee agrees to abide by and be bound by their
      terms and conditions. 

     

    2. Rights
      as Stockholder.
      Until
      the stock certificate evidencing such Shares is issued (as evidenced by the
      appropriate entry on the books of the Company or of a duly authorized transfer
      agent of the Company), no right to vote or receive dividends or any other rights
      as a stockholder shall exist with respect to Shares subject to the Option,
      notwithstanding the exercise of the Option. The Company shall issue (or cause
      to
      be issued) such stock certificate promptly after the Option is exercised. No
      adjustment will be made for a dividend or other right for which the record
      date
      is prior to the date the stock certificate is issued, except as provided in
      Article 11 of the Plan. 

     

    3. Tax
      Consultation.
      Optionee understands that Optionee may suffer adverse tax consequences as a
      result of Optionee’s purchase or disposition of the Shares. Optionee represents
      that Optionee has consulted with any tax consultants Optionee deems advisable
      in
      connection with the purchase or disposition of the Shares and that Optionee
      is
      not relying on the Company for any tax advice.

     

    4. Successors
      and Assigns.
      The
      Company may assign any of its rights under this Agreement to single or multiple
      assignees, and this Agreement shall inure to the benefit of the successors
      and
      assigns of the Company. Subject to the restrictions on transfer herein set
      forth, this Agreement shall be binding upon Optionee and his or her heirs,
      executors, administrators, successors and assigns.

     

    
      
        
        

      

      
        
          EXERCISE
            NOTICE PAGE 1

        

        
          

        

      

      
        
        

      

    

    5. Interpretation.
      Any
      dispute regarding the interpretation of this Agreement shall be submitted by
      Optionee or by the Company forthwith to the Committee, which shall review such
      dispute at its next regular meeting. The resolution of such a dispute by the
      Committee shall be final and binding on the Company and on
      Optionee.

     

    6. Governing
      Law; Severability.
      This
      Agreement shall be governed by and construed in accordance with the laws of
      the
      State of Delaware excluding that body of law pertaining to conflicts of law.
      Should any provision of this Agreement be determined by a court of law to be
      illegal or unenforceable, the other provisions shall nevertheless remain
      effective and shall remain enforceable.

     

    7. Notices.
      Any
      notice required or permitted hereunder shall be given in accordance with the
      provisions set forth in Section 5.5 of the Option Agreement.

     

    8. Further
      Instruments.
      The
      parties agree to execute such further instruments and to take such further
      action as may be reasonably necessary to carry out the purposes and intent
      of
      this Agreement.

     

    9. Entire
      Agreement.
      The
      Plan and Option Agreement are incorporated herein by reference. This Agreement,
      the Plan and the Option Agreement constitute the entire agreement of the parties
      and supersede in their entirety all prior undertakings and agreements of the
      Company and Optionee with respect to the subject matter hereof.

     

    

    
      	
              ACCEPTED
                BY:

            	
              SUBMITTED
                BY:

            
	 	 
	
              SUNESIS
                PHARMACEUTICALS, INC.

            	
              OPTIONEE

            
	 	 
	
              By:
                __________________________________

            	 
	
              Name:
                ________________________________

            	
              Optionee

            
	
              Its:
                __________________________________

            	 
	 	 
	 	
              Address:

               

            
	 	 
	 	 

    

    

    
      
        
        

      

      
        
          EXERCISE
            NOTICE PAGE 2

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