Document:

EMPLOYMENT AGREEMENT

 

This EMPLOYMENT
AGREEMENT (this “Agreement”) with an effective date of May 30, 2014 (the “Effective Date”), is by and
between Cytomedix, Inc., a Delaware corporation (together with its affiliates and subsidiaries, the “Company”), and
Steven A. Shallcross (the “Employee”).

 

WITNESSETH:

 

WHEREAS, the
Employee and the Company previously entered into a letter agreement dated March 30, 2013; and

 

WHEREAS, the
Company and the Employee desire the Employee to continue serving the Company as its Executive Vice President, Chief Financial Officer,
Secretary and Treasurer; and

 

WHEREAS, the
parties desire to provide that the Employee be employed by the Company under the terms of this Agreement.

 

NOW THEREFORE
in consideration of the mutual covenants contained herein as well as other good and valuable consideration, the Company and the
Employee hereby agree as follows:

 

1.             Term
of Employment; Office and Duties.

 

(a)             As
of the Effective Date and subject to the terms and conditions herein, the Company agrees to employ Employee as Executive Vice President,
Chief Financial Officer, Secretary and Treasurer, based in and around the Gaithersburg, MD area. By Employee’s acceptance
of this Agreement, Employee accepts employment in those capacities and shall report to the Company’s Chief Executive Officer
and shall have such reporting relationships to the Audit Committee and the Board of Directors as are required by and set forth
in the Company’s Bylaws, and rules and regulations applicable to the Company. Employee shall have the powers, responsibilities,
restrictions and authorities as are assigned to Employee by the Chief Executive Officer and/or the Board of Directors and shall
devote his full working time and efforts to the best of his ability, experience and talent to the performance of services, duties
and responsibilities as the Company’s Executive Vice President, Chief Financial Officer, Secretary and Treasurer of the Company.
Subject to the terms and conditions set forth herein, Employee specifically acknowledges and accepts such employment and agrees
that both Employee and the Company retain the right to terminate this relationship at any time, with or without cause, for any
reason not prohibited by applicable law upon notice as may be required by this Agreement and otherwise subject to the terms of
this Agreement. Employee acknowledges that nothing in this Agreement is intended to create, nor should be interpreted to create,
a commitment of employment for any specified length of time between the Company and Employee.

 

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(b)             The
Employee shall devote substantially all of his working time to the business and affairs of the Company other than during vacations
of four (4) weeks per year and periods of illness or incapacity; provided, however, that nothing in this Agreement shall preclude
the Employee from devoting time required: (i) delivering lectures or fulfilling speaking engagements; (ii) engaging in charitable
community or industry activities, including sitting on any boards of directors and/or committees of such organizations related
to such activities; or (iii) sitting on not more than two boards of directors of for profit companies provided, however, that such
activities do not interfere with the performance of his duties hereunder. The Employee must obtain the Board’s consent prior
to accepting any such board of directors or board committee memberships, which consent shall not be unreasonably withheld or delayed
by the Board.

 

2.             Compensation
and Benefits.

 

For all services rendered
by the Employee in any capacity during Employee’s employment hereunder, including without limitation, services as an executive
officer or member of any committee of the Board of Directors or any subsidiary, affiliate or division thereof, from and after the
Effective Date the Employee shall be compensated as follows:

 

(a)             Base
Salary. The Company shall pay the Employee a fixed salary (the “Base Salary”) in the gross amount of Two Hundred Ninety
Thousand Dollars ($290,000) per year. The Base Salary is subject to applicable deductions as required by law or authorized
in writing by the Employee. The Board may periodically review the Base Salary with a view to increasing such Base Salary if, in
the judgment of the Board the Employee merits such an increase. The Base Salary will be paid to the Employee in accordance with
the customary payroll practices of the Company.

 

(b)             Annual
Bonus. Upon the conclusion of each Fiscal Year during the Term, provided that the applicable Evaluation Criteria, as defined herein,
have been attained, the Employee shall be entitled to receive an annual bonus (the “Annual Bonus”) of up to 40% of
the Base Salary, 80% of which will be based on the Company performance and 20% on Employee’s personal performance. The “Fiscal
Year” is the period beginning on each January 1 and ending on the following December 31. In order for the Employee to receive
the Annual Bonus, the Evaluation Criteria as established by the Board on the recommendation of the Compensation Committee of the
Board (the "Compensation Committee") for each respective Fiscal Year must, in the sole and absolute determination of
the Board, be attained. As used herein, the term “Evaluation Criteria” refers to such corporate, financial and/or individual
performance goals and objectives for each Fiscal Year as may be determined within the first sixty (60) days such Fiscal Year by
the CEO and Compensation Committee in consultation with the Employee.

 

(c)             The
Annual Bonus, if any, shall be paid to the Employee in a lump sum, cash amount on or before March 15 following the end of the Fiscal
Year to which the Annual Bonus relates. If, before the end of such Fiscal Year, the Employee’s employment with the Company
is terminated by the Company without Cause, or by the Employee for Good Reason, the Employee shall be entitled to receive, at the
time and in the manner set forth in the first sentence of this subparagraph, a pro rata portion of the Annual Bonus that would
have been earned, if any, if the Employee had remained employed until the last day of the Fiscal Year, such pro rata portion to
be determined based upon the Employee’s period of service during such Fiscal Year prior to the termination of employment.
If the Employee’s employment with the Company is terminated for any other reason before the end of a Fiscal Year, the Employee
will not have any right to receive an Annual Bonus, or any portion thereof, for such Fiscal Year.

 

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(d)             Fringe
Benefits, Option Grants and Miscellaneous Employment Matters.

 

(i)             The
Employee shall be entitled to participate in such employee benefit plans or programs, including, without limitation, a Section
401(k) retirement plan, of the Company established and amended and/or terminated from time to time by the Board, available to other
 executives of the Company if any, subject to the terms and conditions of such plans and programs.

 

(ii)         Except
as otherwise provided herein, the Employee may be granted in the sole and absolute discretion of the Board incentive and nonqualified
stock options (the “Employment Options”) on the last business day of each Fiscal Year (provided the Employee is in
the active employment of the Company on such day) to purchase shares of the Company’s common stock (the “Common Stock”)
with an exercise price to be determined in the manner specified in the stock option or equity incentive plan under which the grant
is issued (which shall be no less than the fair market value of the Common Stock on the date of grant). Any such Employment Options
shall be evidenced by a separate agreement between the Company and the Employee, the terms of which will exclusively govern the
Employment Options. Notwithstanding the foregoing, with respect to any Fiscal Year, the Company may grant in its sole and absolute
discretion Employee a form of equity award other than Employment Options, provided that any such award shall have substantially
similar vesting terms as stock options described herein. Employee shall continue to have such rights (if any) to any stock options
granted previously by the Company, in accordance with the terms and conditions of any such options granted.

 

(e)             Withholding
and Employment Tax. The Company will be entitled to deduct and/or withhold from any amounts owing to Employee any federal, state,
city, local or foreign withholding taxes, excise taxes, or employment taxes imposed with respect to Employee’s compensation
or other payments from the Company or Employee’s ownership interest in the Company (including, without limitation, wages,
bonuses, dividends, the receipt or exercise of options and/or other equity interest).

 

(f)             Vacation.
Employee shall receive four (4) weeks of paid vacation annually, administered in accordance with the Company’s existing vacation
policy.

 

(g)             Company
Policies.         Employee agrees to comply to the extent not inconsistent with this
Agreement with all personnel policies and procedures of the Company as the same now exist or may be hereafter implemented by the
Company from time to time, including (without limitation) those policies contained in the Company’s employee manual or handbook
which sets forth policies and procedures generally for employees of the Company. 

 

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3.             Business
Expenses.

 

The Company shall pay
or reimburse all reasonable travel and entertainment expenses incurred by the Employee in connection with the performance of his
duties under this Agreement, including reimbursement for attending out-of-town meetings of the Board in accordance with such procedures
as the Company may from time to time establish for senior officers and as required to preserve any deductions for federal income
taxation purposes to which the Company may be entitled and subject to the Company’s normal requirements with respect to reporting
and documentation of such expenses. Notwithstanding the foregoing, all expenses must be promptly submitted for reimbursement by
the Employee. In no event shall any reimbursement be paid by the Company after the end of the year following the year in which
the expense is incurred by the Employee.

 

4.             Termination
of Employment.

 

Notwithstanding any
other provision of this Agreement, Employee’s employment with the Company may be terminated upon written notice to the other
Party as follows:

 

(a)             By
the Company, in the event of the Employee’s death or Disability (as hereinafter defined) or for Cause (as hereinafter defined).
For purposes of this Agreement, “Cause” shall mean: (i) the conviction of Employee of a crime involving an act or acts
of dishonesty, fraud or moral turpitude, which act or acts constitute a felony; (ii) Employee’s failure, as reasonably
determined by the Board, to substantially perform Employee’s duties hereunder, which failure is not cured within 30 days
from receipt of written notice from the Board specifically setting forth such failure; (iii) Employee having committed acts or
omissions constituting a breach of Employee’s duty of loyalty or fiduciary duty to the Company or any act of dishonesty or
fraud with respect to the Company. A determination that Cause exists shall be made by at least a majority of the members of the
Board, excluding Employee. For purposes of this Agreement, “Disability” shall mean Employee is, by reason of any medically
determinable physical or mental impairment as determined by a licensed physician agreed to by the Company and Executive (or in
the event that Executive and the Company cannot so agree, by a licensed physician agreed upon by a physician selected by Executive
and a physician selected by the Company), which prevents Executive from performing the duties incident to Executive’s employment
hereunder for a continuous period of not less than twelve (12) months, or is determined to be totally disabled by the U.S. Social
Security Administration. The Company shall by written notice to the Employee specify the event relied upon for termination pursuant
to this Section 4(a), and Employee’s employment hereunder shall be deemed terminated as of the date set forth in such notice,
except as otherwise set forth herein. In the event of any termination under Section 4(a), 4(b), 4(c) or 4(d), the Company shall
pay, no later than fourteen (14) days following such termination, all amounts then due to the Employee by the Company under Sections
2(a) of this Agreement for any portion of the payroll period worked and/or any amounts earned but
for which payment had not yet been made up to the date of termination, any unreimbursed business expenses. In such case, any amounts
to which Employee is entitled under the Company’s benefit plans pursuant to Section 2(d)(i) hereof shall be paid in accordance
with the applicable terms and conditions of such plans. If such termination was for Cause, the Company shall have no further obligations
to Employee under this Agreement other than as set forth above and under any outstanding stock option agreements. The Company and
Employee expressly agree that, to the extent Employee’s employment terminates because of death, any amounts payable shall
be made to Employee’s estate, except to the extent otherwise provided under the terms of the instrument pursuant to which
any such amount is paid.

 

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(b)             By
the Company, in the absence of Cause, for any or no reason and in its sole and absolute discretion, provided that in such event
the Company shall, as liquidated damages or severance pay, or both, pay to Employee an (A) amount equal to the monthly Base Salary
(at a monthly rate equal to the rate in effect immediately prior to the date of the termination of the Employee’s employment),
on the same schedule and in the same manner as such payments would have been made in the absence of Employee’s termination,
for a period six (6) months, and (B) COBRA premiums for the Employee and his spouse and dependents under the Company’s group
health plans for a period of twelve (12) months (together, the “Termination Payments”) provided the Release described
in paragraph (f) below has been executed and any revocation period for such Release has expired before the sixtieth (60th) day
after the date of the termination of the Employee’s employment (such 60th day hereinafter called the “Release
Date”). The first payment of the Termination Payments shall be made on the first regular Company pay date that occurs following
the 30th day after the Release Date. The date of termination of employment without cause shall be the date specified
in a written notice of termination to Employee.

 

(c)             By
the Employee for “Good Reason” following (i) a material breach by the Company of the terms and provisions of this Agreement,
(ii) a diminution in Employee’s title authority, duties or responsibilities from title, authority, duty or responsibilities
consistent with the position of Executive Vice President, Chief Financial Officer, Secretary and Treasurer of the Company which,
for the sake of clarity, shall include Employee no longer serving as Executive Vice President, Chief Financial Officer, Secretary
and Treasurer, or (iii) the relocation of the offices of the Company by more than 50 miles without the consent of Employee. Resignation
by Employee for Good Reason shall be communicated by delivery to the Company of a written notice from Employee stating that Employee
shall resign for Good Reason, stating the particulars thereof, and the effective date of the resignation being no later than 180
days from the date of the delivery of the notice (and no sooner than 30 business days). The Company shall have 30 days from the
receipt of such notice to effect a cure of the actions or conditions constituting Good Reason, if and to the extent that such actions
or conditions are subject to cure in the reasonable judgment of the Board. Upon a cure or correction thereof by the Company, such
actions shall no longer constitute Good Reason for purposes of this Agreement and Employee and Company shall agree and acknowledge
in writing the cure of the actions or conditions constituting Good Reason and Employee’s employment shall continue pursuant
to the terms of this Agreement uninterrupted. In the event of a termination by the Employee for Good Reason, the Company shall
pay, as liquidated damages or severance pay, or both, to Employee the same Termination Payments in accordance with the same terms
and conditions as set forth in (b) above.

 

(d)             Employee
may terminate his employment under this Agreement for any other, or no reason upon thirty (30) days prior written notice to the
Company.

 

(e)             In
the event of Employee’s termination by the Company without Cause or by the Employee for Good Reason within sixty (60) days
prior to or during the 12-month period immediately following the consummation of a Change of Control (as defined below) event or
transaction, then subject to Section 4(f), the Employee shall receive the following payments and benefits:

 

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(i)             a
severance payment in an amount equal to the Employee’s annual Base Salary in effect as of the termination date less applicable
deductions and withholdings, which amount shall be payable in a single lump sum within 30 days after the termination date;

 

(ii)         
a lump-sum payment in an amount equal to (A) the monthly COBRA premium in effect under the Company’s group health plan as
of the termination date for the coverage in effect under such plan for the Employee (and his spouse and dependents ) on such date
multiplied by (B) 12, which amount shall be payable in a single lump sum within 30 days after the termination date.; and

 

(iii)        notwithstanding
any provision to the contrary in any applicable equity compensation plan or any outstanding equity award agreement, the treatment
of the Employee’s outstanding equity awards shall be governed solely by the following provisions: (A) all of the Employee’s
then-outstanding equity awards shall fully vest and all restrictions thereon shall lapse, and (B) to the extent vested, all of
the Employee’s outstanding stock options shall remain exercisable until the first to occur of 12 months following the termination
date and each such stock option’s original expiration date.

 

As used herein, the
term “Change in Control” shall mean the occurrence of any of the following circumstances after the date hereof: (i)
any “person” (as such term is used in Section 13(d) or 14(d) of the Securities Exchange Act of 1934 (“Exchange
Act”)), other than a trustee or other fiduciary holding securities under an employee benefit plan of the Company or a corporation
or other entity owned directly or indirectly by the shareholders of the Company in substantially the same proportions as their
ownership of stock of the Company, shall have become the “beneficial owner” (as defined in Rule 13d-3 under the Exchange
Act), directly or indirectly, of securities of the Company representing 30% or more of the combined voting power of the Company’s
then outstanding voting securities; (ii) the Company is a party to a merger, consolidation, share exchange, sale of assets or other
reorganization, or a proxy contest, as a consequence of which members of the Board of Directors in office immediately prior to
such transaction or event constitute less than a majority of the Board thereafter or outstanding shares of common stock of the
Company are converted into securities of another company; or (iii) during any 15-month period, individuals who at the beginning
of such period constituted the Board (including for this purpose any new director whose election or nomination for election by
the Company’s shareholders was approved by a vote of at least two-thirds of the directors then still in office who were directors
at the beginning of such period) cease for any reason to constitute at least a majority of the Board.

 

For the avoidance of
doubt, the payments and benefits described under this Section 4(d) shall be the only payments to which the Employee is entitled
in the event that the Employee’s employment terminates under this Section 4(d). Any payments made to the Employee under Section
4(b) hereof shall offset payments to which the Employee is otherwise entitled under this Section 4(d), and vice versa.

 

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(f)             Any
other provision of this Agreement notwithstanding, the payments and benefits to the Employee set forth in Subsection (b) and (d)
of this Section 4 shall not be paid/provided unless the Employee (i) has timely executed and not revoked a usual and customary
form of general release of all known and unknown claims that the Employee may then have against the Company or persons affiliated
with the Company in the form acceptable to the Company– (the “Release”) and (ii) has agreed not to prosecute
any legal action or other proceeding based upon any of such claims.

 

5.             Confidential
Information

 

All data, literature
and information in any form related to the business of the Company, including, but not limited to, customer lists, know-how, trade
secrets, product specifications, methods and techniques, and process information, whether such information is written or oral,
or which is developed, discovered or created by Employee or the Company during Employee’s employment by the Company will
be considered confidential and proprietary data of the Company for the duration of such employment and thereafter, whether or not
it is expressly designated proprietary or confidential (the "Confidential Information"). Employee will not disclose,
reveal, transfer or use (except within the scope of his duties) the Confidential Information to or with any other person, third
party, company or otherwise, without the prior written authorization of the Company. All Confidential Information shall remain
the property of the Company and shall be promptly returned to the Company at its request, but in any event immediately upon termination
of Employee's employment hereunder, with all copies or excerpts made therefrom. The term "Confidential Information" shall
not include information which is or becomes publicly available without breach of (a) this Agreement, (b) any other agreement to
which the Company is a party or beneficiary, or (c) any duty owed to the Company by Employee or any third party or (d) information
required to be disclosed by any governmental authority; provided that, if Employee desires to use any such information for any
reason, Employee shall bear the burden of proving that such information has become publicly available without any such breach.

 

6.             Restrictive
Covenants

 

(a)             Noncompete.
In order to protect the goodwill and business and professional relationships of the Company, Employee agrees that he will not during
the term of his employment with the Company and for a period of six (6) months following termination of his employment with the
Company, directly or indirectly, either as an individual for his own account or enterprise, or as a partner, owner, joint venturer,
officer, director, employee, agent, salesman, independent contractor, supplier, principal, consultant, or 1% or more owner of any
entity or third party.

 

(i)             Compete
(as hereinafter defined) with the Company anywhere in the Restricted Area (as hereinafter defined). For purposes of this Section
6(a) "Compete" means to engage, participate or be involved in any respect in any business that is competitive with the
Company, or furnishing any aid, assistance or service of any kind to any person or entity which competes with the business of the
Company, and (ii) "Restricted Area" means the continental United States;

 

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(ii)         hire
or solicit for employment or as an independent contractor, directly or indirectly, any of the Company's personnel in any capacity
whatsoever (which shall be deemed to include, without limitation, any existing or (to Employee’s knowledge), prospective
employee, consultant or independent contractor of the Company);

 

(iii)        attempt
directly or indirectly to induce any of the Company's personnel to leave the employ of, or discontinue such person's consultant,
contractor, or other business association with the Company;

 

(iv)        solicit
business that is competitive with the Company directly or indirectly from any client of the Company. For purposes hereof, a person
or entity is a "client of the Company" if the Company is performing, has performed during the previous twelve (12) months,
or to the knowledge of the Employee is contemplating performing at such time, services for such person or entity; or

 

(v)         interfere
with, disrupt or attempt to disrupt the business relationships, contractual or otherwise, between the Company and any of its agents,
clients, licensors, licensees, suppliers, employees or independent contractors, including, without limitation, by inducing any
client to become a client of any company or entity whose business competes with the Company.

 

(b)             Reasonableness
of Restraints. Employee acknowledges that:

 

(i)             The
imposition of restrictions, restraints and limitations set forth in Section 6 hereof are necessary for the reasonable and adequate
protection of the Company's business and do not prevent Employee from earning a living.

 

(ii)         Each
and every restriction, restraint and limitation set forth in Section 6 hereof is reasonable in respect to geographic area, subject
matter and length of time.

 

(c)             Remedies.
If Employee were to breach the covenants contained in Section 5 or 6 hereof, monetary damages alone would not adequately compensate
the Company. In addition to all remedies available at law or in equity, in the event that Employee breaches the covenants contained
in Section 5 or 6 hereof, the Company shall be entitled to seek interim restraints and permanent injunctive relief for the enforcement
thereof. The duration of Employee's covenants set forth in Section 6 also shall be extended by a period of time equal to the number
of days, if any, during which Employee is in violation of the provisions contained in Section 6. All of the rights and remedies
of the parties hereto shall be cumulative with, and in addition to, any other rights, remedies or causes of action allowed by law
or equity and shall not exclude any other rights or remedies available to either of the parties hereto.

 

(d)             Binding
Restrictions; Severability. Employee will continue to be bound by the restrictions of Section 5 or 6 until their expiration,
and shall not be entitled to any additional compensation from the Company with respect thereto. If at any time the provisions of
this Section 5 or 6 shall be determined to be invalid or unenforceable, by reason of being vague or unreasonable as to area, duration
or scope of activity, the same shall be considered divisible and shall become and be immediately amended to only such area, duration
and scope of activity as shall be determined to be reasonable and enforceable by the court or other body having jurisdiction over
the matter; and Employee agrees that Section 5 or 6 as so amended shall be valid and binding as though any invalid or unenforceable
provision had not been included herein.

 

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(e)             Other
Obligations. The restrictive covenants set forth in Section 5 and 6 hereof shall be in addition to, and not in lieu of, any
obligations which any party may have with respect to the subject matter hereof, whether by contract, as a matter of law or otherwise.
In the event of any conflict between the provisions of Section 5 or 6 and any such other obligations, those that provide the Company
with the broadest and most effective protection shall apply.

 

(f)             Non-Disparagement.
Employee shall not, either during or after the term of his employment with the Company, make any statements, whether oral or in
writing, that would tend to disparage or defame the Company, its products, services, employees, officers, managers or members of
the Board. Neither the Company, nor any officer, director, employee, agent or affiliate will, either during or after the term Employee’s
employment with the Company, make any statement, whether oral or in writing, that would tend to disparage or defame the Employee.

 

(g)             Property
of the Company. Employee agrees that all records, files, memoranda, reports, client lists, programs, work product, or any other
similar records or documents relating to the Company's business (including without limitation those which may have been used or
prepared by Employee, whether or not part of the Confidential Information), remain the sole personal property of the Company and
remain at all times, both during and after Employee's employment with the Company, in the control of the Company. Employee hereby
waives and releases all claims of right of ownership thereto and Employee hereby agrees that upon the termination of his employment
with the Company for any reason whatsoever, Employee shall immediately surrender all such records and documents, and all copies
thereof, together with any other property of the Company in Employee's possession, to the Company at its principal business office
or such other location as directed by the Company.

 

(h)             Notification
to New Employer. In the event that Employee leaves the employ of the Company, Employee hereby gives his consent to notification
by the Company to his new employer about Employee's obligations under this Agreement, including providing such new employer a copy
of this Agreement. The Company shall provide Employee a copy of such written notification (if any) given to Employee's new employer
pursuant to the immediately preceding sentence. Employee hereby agrees to provide (prior to his commencement of employment with
such new employer) any such new employer a copy of this Agreement.

 

(i)             Survival
of Restraints. The provisions of Section 5 and 6 shall survive the termination of Employee's employment with the Company, whether
such termination is voluntary or involuntary, with or without cause, for any reason whatsoever.

 

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7.             Dispute
Resolution.

 

All disputes between
the Parties arising from the construction or performance of, or otherwise in connection with this Agreement, shall be finally settled
in Maryland, before one arbitrator pursuant to the rules of the American Arbitration Association. The arbitration procedure and
all decisions made by the arbitrator shall be kept confidential, unless the Parties expressly consent to the publication thereof
in whole or in part. Unless oral hearings are requested by a party, the arbitrator shall make his/her award on the basis of written
submissions. In the event of any proceeding between the Company and the Employee with respect to the subject matter of this Agreement
and the enforcement of the rights hereunder and such proceeding results in final judgment or order in favor of one of the Parties,
which judgment or order is substantially inconsistent with the positions asserted by the other Party in such litigation or proceeding,
the losing Party in such event shall reimburse the prevailing Party for all of its reasonable costs and expenses relating to such
litigation or other proceeding, including, without limitation, its reasonable attorneys’ fees and expenses. Such payments
shall be made no later than sixty (60) days after the final judgment or order is entered.

 

8.             Consolidation;
Merger; Sale of Assets; Change of Control.

 

Nothing in this Agreement
shall preclude the Company from combining, consolidating or merging with or into, transferring all or substantially all of its
assets to, or entering into a partnership or joint venture with, another corporation or other entity, or effecting any other kind
of business combination provided that the entity resulting from or surviving such combination, consolidation or merger, or to which
such assets are transferred, or such partnership or joint venture, assumes this Agreement and all obligations and undertakings
of the Company hereunder. Upon such a consolidation, merger, transfer of assets or formation of such partnership or joint venture,
this Agreement shall inure to the benefit of, be assumed by, and be binding upon such resulting or surviving transferee corporation
or such partnership or joint venture, and the term “Company,” as used in this Agreement, shall mean such corporation,
partnership or joint venture or other entity, and this Agreement shall continue in full force and effect in accordance with its
terms and shall entitle the Employee and his heirs, beneficiaries and representatives to substantially the same compensation, benefits,
payments and other rights, including but not limited to those provided for in Section 4(d) hereof, as would have been their entitlement
had such combination, consolidation, merger, transfer of assets or formation of such partnership or joint venture not occurred.

 

9.             Survival
of Obligations.

 

Sections
2(c), 2(e), 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20 and 21 shall survive the termination for
any reason of this Agreement (whether such termination is by the Company, by the Employee, upon the expiration of this Agreement
or otherwise).

 

10.         Employee’s
Representations.

 

The
Employee hereby represents and warrants to the Company that (i) the execution, delivery and performance of this Agreement by the
Employee do not and shall not conflict with, breach, violate or cause
a default under any contract, agreement, instrument, order, judgment or decree to which the Employee is a party or by which he
is bound, (ii) the Employee is not a party to or bound by any employment agreement, non-compete agreement or confidentiality agreement
with any other person or entity and (iii) upon the execution and delivery of this Agreement by the Company and the Employee, this
Agreement shall be the valid and binding obligation of the Employee, enforceable in accordance with its terms. The Employee hereby
acknowledges and represents that he has consulted with legal counsel regarding his rights and obligations under this Agreement
and that he fully understands the terms and conditions contained herein.

 

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11.         Company’s
Representations.

 

The
Company hereby represents and warrants to the Employee that (i) the execution, delivery and performance of this Agreement
by the Company do not and shall not materially conflict with, breach, violate or cause a default under any contract, agreement,
instrument, order, judgment or decree to which the Company is a party or by which it is bound and (ii) upon the execution and delivery
of this Agreement by the Employee and the Company, this Agreement shall be the valid and binding obligation of the Company, enforceable
in accordance with its terms.

 

12.         Enforcement.

 

Because the Employee’s
services are unique and because the Employee has access to confidential information concerning the Company, the parties hereto
agree that money damages alone may not be an adequate remedy for any breach of this Agreement. Therefore, in the event of a breach
or threatened breach of this Agreement, the Company may, in addition to other rights and remedies existing in its favor, apply
to any court of competent jurisdiction in Maryland for injunctive relief in order to enforce, or prevent any violations of, the
provisions hereof (without posting a bond or other security).

 

13.         Severability.

 

In case any one or
more of the provisions or part(s) of provisions contained in this Agreement shall for any reason be held to be invalid, illegal
or unenforceable in any respect in any jurisdiction, such invalidity, illegality or unenforceability shall be deemed not to affect
any other jurisdiction or any other provision or part of a provision of this Agreement, nor shall such invalidity, illegality or
unenforceability affect the validity, legality or enforceability of this Agreement or any provision or provisions hereof in any
other jurisdiction; and this Agreement shall be reformed and construed in such jurisdiction as if such provision or part of a provision
held to be invalid or illegal or unenforceable had never been contained herein and such provision or part reformed so that it would
be valid, legal and enforceable in such jurisdiction to the maximum extent possible. If, in any judicial proceeding, a court shall
refuse to enforce any of such separate covenants, then such unenforceable covenants shall be deemed eliminated from the provisions
hereof for the purpose of such proceedings to the extent necessary to permit the remaining separate covenants to be enforced in
such proceedings. If, in any judicial proceeding, a court shall refuse to enforce any one or more of such separate covenants because
the total time, scope or area thereof is deemed to be excessive or unreasonable, then it is the intent of the parties hereto that
such covenants, which would otherwise be unenforceable due to such excessive or unreasonable period of time, scope or area, be
enforced for such lesser period of time, scope or area as shall be deemed reasonable and not excessive by such court.

  

    	Page 11 of 14

    	 

    

  

14.         Entire
Agreement; Amendment; Indemnification; Fees.

 

(a)             Entire
Agreement. Except as otherwise set forth in this Agreement, this Agreement contains the entire agreement between the Company
and the Employee with respect to the subject matter hereof and thereof and supersedes and nullifies all previous agreements between
the parties about the Company’s employment of the Employee. This Agreement may not be amended, waived, changed, modified
or discharged except by an instrument in writing executed by or on behalf of the party against whom enforcement of any amendment,
waiver, change, modification or discharge is sought. No course of conduct or dealing shall be construed to modify, amend or otherwise
affect any of the provisions hereof.

 

(b)             Indemnification.
The Company shall enter into an Indemnification Agreement with Employee that is customary for an executive officer of a public
reporting company and in the same form as provided to the members of the Board of Directors.

 

(c)             Reimbursement.
The Company will reimburse Employee an amount not to exceed $7,500 for legal fees relating to the review of this Agreement by counsel
on behalf of Employee.

 

15.         Notices.

 

All notices, requests,
demands and other communications hereunder shall be in writing and shall be deemed to have been duly given if physically delivered,
delivered by express mail or other expedited service or upon receipt if mailed, postage prepaid, via registered mail, return receipt
requested, addressed as follows:

 

	(a)	To the Company:	(b)	To the Employee:
	 	 	 	 
	Cytomedix, Inc.	Steven A. Shallcross
	209 Perry Parkway, Suite 7	 
	Gaithersburg, MD 20877	 
	Attn: Chairman of the Compensation Committee

 

and/or to such other
persons and addresses as any party shall have specified in writing to the other.

 

16.         Assignability.

 

This
Agreement shall be assignable by the Company but not the Employee, and shall be binding upon, and shall inure to the benefit of,
the heirs, executors, administrators, legal representatives, successors and permitted assigns of the parties. In the event that
all or substantially all of the business of the Company is sold or transferred, then this Agreement shall be binding on the transferee
of the business of the Company whether or not this Agreement is expressly assigned to the transferee.
This Agreement shall inure to the benefit of and be enforceable by the Employee’s personal or legal representatives, executors,
administrators, successors, heirs, distributees, devisees and legatees. 

 

    	Page 12 of 14

    	 

    

  

17.         Governing
Law.

 

This
Agreement shall be governed by and construed under the laws of
the State of Delaware. 

 

18.         Waiver
and Further Agreement.

 

Any waiver of any breach
of any terms or conditions of this Agreement shall not operate as a waiver of any other breach of such terms or conditions or any
other term or condition, nor shall any failure to enforce any provision hereof operate as a waiver of such provision or of any
other provision hereof. Each of the parties hereto agrees to execute all such further instruments and documents and to take all
such further action as the other party may reasonably require in order to effectuate the terms and purposes of this Agreement.

 

19.         Headings
of No Effect.

 

The paragraph headings
contained in this Agreement are for reference purposes only and shall not in any way affect the meaning or interpretation of this
Agreement.

 

20.         Section
409A of the Internal Revenue Code.

 

Each payment under
this Agreement is intended to be exempt from Section 409A of the Internal Revenue Code of 1986, as amended (the “Code”)
or in compliance with Code Section 409A, and the provisions of this Agreement will be administered, interpreted and construed accordingly.
Without limiting the generality of the foregoing, the term “termination of employment” or any similar term under this
Agreement will be interpreted to mean “separation from service” within the meaning of Code Section 409A to the extent
necessary to comply with Code Section 409A. Furthermore, the right to a series of installment payments or in-kind benefits under
this Agreement is to be treated as a right to a series of separate payments for purposes of Code Section 409A.

 

Notwithstanding anything
in this Agreement to the contrary, for any year in which the stock of the Company is tradable on an established securities market,
and the Employee meets the requirements of Code Section 416(i)(1)(A)(i), (ii), or (iii) (applied in accordance with the regulations
thereunder, but without regard to Code Section 416(i)(5)) at any time during the 12 month period ending on the last occurring December 31st
(and is therefore a “Specified Employee”), then, to the extent required by Code Section 409A, and the final regulations
thereunder, the Company shall pay any benefit which constitutes “deferred compensation” under this Agreement within
the meaning of the Code Section 409A no earlier than the earliest of the following:

 

(1)         the
expiration of the six month period (the “Deferral Period”) measured from the date of the Employee’s ‘separation
from service’ under Code Section 409A; or

 

(2)         the
date of the Employee’s death.

 

    	Page 13 of 14

    	 

    

 

Upon
the expiration of the Deferral Period, all payments of deferred compensation that would have been made during the Deferral Period
(whether in a single lump sum or in installments) shall be paid as a single lump sum to the Employee or, if applicable, his or
her beneficiary. This section shall not apply to any payment which constitutes “separation pay” as described in Treasury
Regulation 1.409A-1(b)(9)(iii) or which constitute a “short-term deferral” as described in Treasury Regulation 1.409A-1(b)(4).

 

To the extent required
by Code Section 409A, with regard to any provision that provides for the reimbursement of costs and expenses, or for the provision
of in-kind benefits:

 

(1)         The
right to such reimbursement or in-kind benefit shall not be subject to liquidation or exchange for another benefit;

 

(2)         The
amount of expenses or in kind benefits available or paid in one year shall not affect the amount available or paid in any subsequent
year; and

 

(3)         Such
payments shall be made on or before the last day of the Employee’s taxable year following the taxable year in which the expense
occurred.

 

21.         Code
Section 280G

 

Notwithstanding anything
contained in this Agreement to the contrary, to the extent that any of the payments and benefits provided for under this Agreement,
together with any payments or benefits under any other agreement or arrangement between the Company or any of their subsidiaries
or affiliates and Employee (collectively, the “Payments”) would constitute a “parachute payment”
within the meaning of Section 280G of the Code, Employee shall receive total payments equal to the greater, after the application
of the excise tax imposed pursuant to Section 4999 of the Code, of the Payments provided under this Agreement or the amount of
such Payments reduced to the greatest amount that would result in no portion of the Payments being subject to such excise tax.

 

IN WITNESS WHEREOF,
the parties hereto have executed this Employment Agreement as of the date first above written.

 

	 	 	COMPANY:
	 	 	 
	 	 	CYTOMEDIX, INC.
	 	 	 
	 	By:	/s/ Martin Rosendale
	 	 	Martin Rosendale
	 	 	Chief Executive Officer
	 	 	 
	 	 	EMPLOYEE:
	 	 	 
	 	 	/s/ Steven A. Shallcross
	 	 	Steven A. Shallcross

 

    	Page 14 of 14EMPLOYMENT AGREEMENT

 

This EMPLOYMENT
AGREEMENT (this “Agreement”) with an effective date of May 30, 2014 (the “Effective Date”), is by and
between Cytomedix, Inc., a Delaware corporation (together with its affiliates and subsidiaries, the “Company”), and
Dean Tozer (the “Employee”).

 

WITNESSETH:

 

WHEREAS, the
Employee and the Company previously entered into a letter agreement dated March 30, 2014; and

 

WHEREAS, the
Company and the Employee desire the Employee to continue serving as Executive Vice President, Chief Commercial Officer; and

 

WHEREAS, the
parties desire to provide that the Employee be employed by the Company under the terms of this Agreement.

 

NOW THEREFORE
in consideration of the mutual covenants contained herein as well as other good and valuable consideration, the Company and the
Employee hereby agree as follows:

 

1.           Term
of Employment; Office and Duties.

 

(a)          Unless
earlier terminated as provided herein, the term of this Agreement (the “Term”) shall be for a period of thirty (30)
months commencing on the Effective Date. During the Term, and subject to the terms and conditions herein, the Company agrees to
employ Employee as Executive Vice President, Chief Commercial Officer, based in and around the Nashville, TN area. By Employee’s
acceptance of this Agreement, Employee accepts employment in those capacities. Employee shall report to the Company’s Chief
Executive Officer and shall have such reporting relationships to the Board of Directors as are required by and set forth in the
Company’s Bylaws, and rules and regulations applicable to the Company. Employee shall have the powers, responsibilities,
restrictions and authorities as are assigned to Employee by the Chief Executive Officer and/or the Board of Directors and shall
devote his full working time and efforts to the best of his ability, experience and talent to the performance of services, duties
and responsibilities as the Company’s Executive Vice President, Chief Commercial Officer.

 

(b)          The
Employee agrees to provide the services set forth hereunder on a full-time basis and to devote all necessary time and attention
to the furtherance of the business and interests of the Company, and to perform his duties set forth herein diligently and promptly
for the benefit of Company, strictly and faithfully upholding the Company’s policies; provided, however, that nothing in
this Agreement shall preclude the Employee from devoting time required: (i) delivering lectures or fulfilling speaking engagements;
and (ii) engaging in charitable and community activities, including sitting on any boards of directors and/or committees of such
organizations related to such activities; provided, however, that such activities do not unreasonably interfere with the performance
of his duties hereunder. Notwithstanding the above, Employee may with the prior consent of the Board and prior written consent
of the Chief Executive Officer of the Company (such consent not to be unreasonably withheld) pursue during his employment hereunder
other business interests.

 

    	Page 1 of 14

    	 

    

 

2.           Compensation
and Benefits.

 

For all services rendered
by the Employee in any capacity during Employee’s employment hereunder, including without limitation, services as an executive
officer or member of any committee of the Board of Directors or any subsidiary, affiliate or division thereof, from and after the
Effective Date the Employee shall be compensated as follows:

 

(a)          Base
Salary. The Company shall pay the Employee a fixed salary (the “Base Salary”) in the gross amount of Three Hundred
Thousand Dollars ($300,000) per year. The Base Salary is subject to applicable deductions as required by law or authorized in writing
by the Employee. The Board may periodically review the Base Salary with a view to increasing such Base Salary if, in the judgment
of the Board the Employee merits such an increase. Any increase in Base Salary which has been approved by the Board shall constitute
“Base Salary” hereunder.  The Base Salary will be paid to the Employee in accordance with the customary payroll
practices of the Company.

 

(b)          Annual
Bonus. Upon the conclusion of each Fiscal Year during the Term, provided that the applicable Evaluation Criteria, as defined herein,
have been attained, the Employee shall be entitled to receive an annual bonus in the amount of 40% of your Base Salary (the “Annual
Bonus”). The “Fiscal Year” is the period beginning on each January 1 and ending on the following December 31.
In order for the Employee to receive the Annual Bonus, the Evaluation Criteria as established by the Board on the recommendation
of the Compensation Committee of the Board (the "Compensation Committee"), in consultation with the Company’s Chief
Executive Officer and the Employee, for each respective Fiscal Year mustbe satisfied, such that eighty percent (80%) of the Annual
Bonus shall be based upon the Company’s corporate and financial performance goals during the applicable Fiscal Year and twenty
percent (20%) of the Annual Bonus shall be based upon the Employee’s individual performance goals. As used herein, the term
“Evaluation Criteria” refers to such corporate, financial and/or individual performance goals and objectives for each
Fiscal Year as may be determined within the first sixty (60) days such Fiscal Year by the CEO and Compensation Committee in consultation
with the Employee.

 

(c)          The
Annual Bonus, if any, shall be paid to the Employee in a lump sum, cash amount on or before March 15 following the end of the Fiscal
Year to which the Annual Bonus relates. If, before the end of such Fiscal Year, the Employee’s employment with the Company
is terminated by the Company without Cause, or by the Employee for Good Reason, the Employee shall be entitled to receive, at the
time and in the manner set forth in the first sentence of this subparagraph, a pro rata portion of the Annual Bonus that would
have been earned, if any, if the Employee had remained employed until the last day of the Fiscal Year, such pro rata portion to
be determined based upon the Employee’s period of service during such Fiscal Year prior to the termination of employment.
If the Employee’s employment with the Company is terminated for any other reason before the end of a Fiscal Year, the Employee
will not have any right to receive an Annual Bonus, or any portion thereof, for such Fiscal Year.

 

    	Page 2 of 14

    	 

    

 

(d)          Fringe
Benefits, Option Grants and Miscellaneous Employment Matters.

 

(i)          The
Employee shall be entitled to participate in such employee benefit plans or programs, including, without limitation, a Section
401(k) retirement plan, of the Company established and amended and/or terminated from time to time by the Board, available to other
 executives of the Company if any, subject to the terms and conditions of such plans and programs.

 

(ii)         Except
as otherwise provided herein, the Employee may be granted in the sole and absolute discretion of the Board incentive and nonqualified
stock options (the “Employment Options”) on the last business day of each Fiscal Year (provided the Employee is in
the active employment of the Company on such day) to purchase shares of the Company’s common stock (the “Common Stock”)
with an exercise price to be determined in the manner specified in the stock option or equity incentive plan under which the grant
is issued (which shall be no less than the fair market value of the Common Stock on the date of grant). Any such Employment Options
shall be evidenced by a separate agreement between the Company and the Employee, the terms of which will exclusively govern the
Employment Options. Notwithstanding the foregoing, with respect to any Fiscal Year, the Company may grant in its sole and absolute
discretion Employee a form of equity award other than Employment Options, provided that any such award shall have substantially
similar vesting terms as the nonqualified stock options described herein. Employee shall continue to have such rights (if any)
to any stock options granted previously by the Company, including but not limited to the stock options granted to Employee on April
8, 2014 evidenced by the minutes of the April 8, 2014 Board Meeting whereby Employee shall have the right to purchase 1,540,800
shares of common stock upon the exercise of such options, in accordance with the terms and conditions of any such options granted.

 

(e)          Withholding
and Employment Tax. The Company will be entitled to deduct and/or withhold from any amounts owing to Employee any federal, state,
city, local or foreign withholding taxes, excise taxes, or employment taxes imposed with respect to Employee’s compensation
or other payments from the Company or Employee’s ownership interest in the Company (including, without limitation, wages,
bonuses, dividends, the receipt or exercise of options and/or other equity interest).

 

(f)          Vacation.
Employee shall receive four (4) weeks of paid vacation annually, administered in accordance with the Company’s existing vacation
policy.

 

(g)          Company
Policies.         Employee agrees to comply to the extent not inconsistent with this
Agreement with all personnel policies and procedures of the Company as the same now exist or may be hereafter implemented by the
Company from time to time, including (without limitation) those policies contained in the Company’s employee manual or handbook
which sets forth policies and procedures generally for employees of the Company. 

 

    	Page 3 of 14

    	 

    

 

3.           Business
Expenses.

 

The Company shall pay
or reimburse all reasonable travel and entertainment expenses incurred by the Employee in connection with the performance of his
duties under this Agreement, including such travel as may be required or appropriate in your discretion, consistent with duly approved
Company guidelines and budgets, to fulfill the responsibilities of your office, all in accordance with such procedures as the Company
may from time to time establish for senior officers and as required to preserve any deductions for federal income taxation purposes
to which the Company may be entitled and subject to the Company’s normal requirements with respect to reporting and documentation
of such expenses.

 

4.           Termination
of Employment.

 

Notwithstanding any
other provision of this Agreement, Employee’s employment with the Company may be terminated during the Term upon written
notice to the other Party as follows:

 

(a)          By
the Company, in the event of the Employee’s death or Disability (as hereinafter defined) or for Cause (as hereinafter defined).
For purposes of this Agreement, “Cause” shall mean: (i) the conviction of Employee of a crime involving an act or acts
of dishonesty, fraud or moral turpitude, which act or acts constitute a felony; (ii) Employee’s refusal to perform the
duties and responsibilities required of him hereunder or (iii) Employee’s willfully engaging in conduct that is, in the Board’s
reasonable determination, materially injurious to the Company or its affiliates (monetarily or otherwise). A determination that
Cause exists shall be made by at least a majority of the members of the Board. Furthermore, the foregoing events or conditions
will not constitute Cause unless Company provides Employee with written notice of the event or condition and fifteen (15) days
to cure such event or condition (if curable) and the event or condition is not cured within such 15-day period. For purposes of
this Agreement, “Disability” shall mean a determination that Employee suffers from illness or other physical or mental
impairment that prevents Executive from substantially performing his duties for a period of 180 days during any consecutive 360-day
period during the Term. The determination of whether (and, if appropriate, when) a Disability has occurred shall be made by two
licensed physicians, one chosen by a majority of the Board and one chosen by Employee (or his personal representative); provided,
however, that if the two physicians do not agree with respect to whether (or, if appropriate, when) a Disability has occurred,
such determination shall be made by a third licensed physician chosen by said two physicians. The Company shall by written notice
to the Employee specify the event relied upon for termination pursuant to this Section 4(a), and Employee’s employment hereunder
shall be deemed terminated as of the date set forth in such notice (such date having incorporated applicable cure periods), except
as otherwise set forth herein. In the event of the expiration of the Term or any termination under Section 4(a), 4(b), 4(c)4(d)
or 4(e) the Company shall pay, no later than fourteen (14) days following such termination, all amounts then due to the Employee
by the Company under Sections 2(a),2(b) and 2(c) of this Agreement for any portion of the payroll period worked and/or any amounts
earned but for which payment had not yet been made up to the date of termination, any unreimbursed business expenses and any amounts
to which Employee is entitled under the Company’s benefit plans pursuant to Section 2(d) hereof shall be paid in accordance
with the applicable terms and conditions of such plans. If such termination was for Cause or results from the expiration of the
Term, the Company shall have no further obligations to Employee under this Agreement. The Company and Employee expressly agree
that, to the extent Employee’s employment terminates because of death, any amounts payable shall be made to Employee’s
estate, except to the extent otherwise provided under the terms of the instrument pursuant to which any such amount is paid.

 

    	Page 4 of 14

    	 

    

 

(b)          By
the Company, in the absence of Cause, for any or no reason and in its sole and absolute discretion, upon thirty (30) days prior
written notice to the Employee provided that in such event the Company shall pay to Employee after the termination date (A) an
amount equal to the monthly Base Salary (at a monthly rate equal to the rate in effect immediately prior to the date of the termination
of the Employee’s employment) on the same schedule and in the same manner as such payments would have been made in the absence
of Employee’s termination, for a period of six (6) months, and (B) COBRA premiums for the Employee and his dependants under
the Company’s employee benefit plans for a period of twelve (12) months on the same schedule and in the same manner as such
payments would have been made in the absence of Employee’s termination (together, the “No Cause Termination Payments”)
provided the Release described in paragraph (f) below has been executed and any revocation period for such Release has expired
(the “Release Date”). The first payment of the No Cause Termination Payments shall be made on the first regular Company
pay date that occurs following the Release Date.

 

(c)          By
the Employee for “Good Reason” following (i) a material breach by the Company of the terms and provisions of this Agreement,
(ii) a requirement to relocate from Nashville, TN, (iii) a diminution in Employee’s title authority, duties or responsibilities
from title, authority, duty or responsibilities consistent with the position of Executive Vice President, Chief Commercial Officer
of the Company. Resignation by Employee for Good Reason shall be communicated by delivery to the Company of a written notice from
Employee stating that Employee shall resign for Good Reason, stating the particulars thereof, and the effective date of the resignation
being no later than 180 days from the date of the delivery of the notice (and no sooner than 30 business days). The Company shall
have 30 days from the receipt of such notice to effect a cure of the actions or conditions constituting Good Reason, if and to
the extent that such actions or conditions are subject to cure in the reasonable judgment of the Board. Upon a cure or correction
thereof by the Company, such actions shall no longer constitute Good Reason for purposes of this Agreement and Employee and Company
shall agree and acknowledge in writing the cure of the actions or conditions constituting Good Reason and Employee’s employment
shall continue pursuant to the terms of this Agreement uninterrupted. In the event of a termination by the Employee for Good Reason,
the Company shall pay, as liquidated damages or severance pay, or both, to Employee the same Termination Payments in accordance
with the same terms and conditions as set forth in (b) above.

 

    	Page 5 of 14

    	 

    

 

(d)         Employee
may terminate his employment under this Agreement for no reason upon thirty (30) days prior written notice to the Company.

 

(e)         In
the event of Employee’s termination by the Company without Cause or by the Employee for Good Reason within sixty (60) days
prior to or during the twelve (12)month period following the consummation of a Change of Control (as defined below), then provided
that the Release described in paragraph (f) below has been executed, the Employee shall receive the following payments and benefits:

 

(i)          a
severance payment in an amount equal to the Employee’s annual Base Salary in effect as of the termination date less applicable
deductions and withholdings, which amount shall be payable in a single lump sum within 30 days after the termination date.

 

(ii)         a
lump-sum payment in an amount equal to (A) the monthly COBRA premium in effect under the Company’s group health plan as of
the termination date for the coverage in effect under such plan for the Employee (and his spouse and dependents ) on such date
multiplied by (B) 12, which amount shall be payable in a single lump sum within 30 days after the termination date; and

 

(iii)        notwithstanding
any provision to the contrary in any applicable equity compensation plan or any outstanding equity award agreement, the treatment
of the Employee’s outstanding equity awards shall be governed solely by the following provisions: (A) all of the Employee’s
then-outstanding equity awards shall fully vest and all restrictions thereon shall lapse, and (B) to the extent vested, all of
the Employee’s outstanding stock options shall remain exercisable until the first to occur of 12 months following the termination
date and each such stock option’s original expiration date.

 

As used herein, the
term “Change in Control” shall mean the occurrence of any of the following circumstances after the date hereof: (i)
any “person” (as such term is used in Section 13(d) or 14(d) of the Securities Exchange Act of 1934 (“Exchange
Act”)), other than a trustee or other fiduciary holding securities under an employee benefit plan of the Company or a corporation
or other entity owned directly or indirectly by the shareholders of the Company in substantially the same proportions as their
ownership of stock of the Company, shall have become the “beneficial owner” (as defined in Rule 13d-3 under the Exchange
Act), directly or indirectly, of securities of the Company representing 30% or more of the combined voting power of the Company’s
then outstanding voting securities; (ii) the Company is a party to a merger, consolidation, share exchange, sale of assets or other
reorganization, or a proxy contest, as a consequence of which members of the Company’s Board of Directors (the “Board”)
in office immediately prior to such transaction or event constitute less than a majority of the Board thereafter; or (iii) during
any 15-month period, individuals who at the beginning of such period constituted the Board (including for this purpose any new
director whose election or nomination for election by the Company’s shareholders was approved by a vote of at least two-thirds
(2/3) of the directors then still in office who were directors at the beginning of such period) cease for any reason to constitute
at least a majority of the Board.

 

    	Page 6 of 14

    	 

    

 

For the avoidance of
doubt, the payments and benefits described under this Section 4(e) shall be the only payments to which the Employee is entitled
in the event that the Employee’s employment terminates under this Section 4(e). Any payments made to the Employee under Section
4(b) or 4(c) hereof shall offset payments to which the Employee is otherwise entitled under this Section 4(e), and vice versa.

 

(f)          Any
other provision of this Agreement notwithstanding, the payments and benefits to the Employee set forth in Subsection (b) and (d)
of this Section 4 shall not be paid/provided unless the Employee (i) has timely executed and not revoked a usual and customary
general release of all known and unknown claims that the Employee may then have against the Company or persons affiliated with
the Company in the form reasonably acceptable to the Company (the “Release”) and (ii) has agreed not to prosecute any
legal action or other proceeding based upon any of such claims.

 

5.           Confidential
Information

 

The parties hereto recognize
that a major need of the Company is to preserve its specialized knowledge, trade secrets, and confidential information. The strength
and good will of the Company is derived from the specialized knowledge, trade secrets, and confidential information generated from
experience with the activities undertaken by the Company and its affiliates. The disclosure of this information and knowledge to
competitors would be beneficial to them and detrimental to the Company, as would the disclosure of information about the marketing
practices, pricing practices, costs, profit margins, design specifications, analytical techniques, and similar items of the Company
and its affiliates. The Employee acknowledges that the proprietary information, observations and data that will be obtained by
him while employed by the Company concerning the business or affairs of the Company are the property of the Company. By reason
of him being a senior executive of the Company, the Executive has or will have access to, and has obtained or will obtain, specialized
knowledge, trade secrets and confidential information about the Company’s operations and the operations of its subsidiaries,
which operations extend throughout the United States. Employee shall not, without the prior written consent of the Company, use,
divulge, disclose or make accessible to any other person, firm, partnership, corporation or other entity any Confidential Information
(as defined below) pertaining to the business of the Company or any of its affiliates, except (i) while employed by the Company,
in the business of and for the benefit of the Company, or (ii) when required to do so by a court of competent jurisdiction,
by any governmental agency having supervisory authority over the business of the Company, or by any administrative body or legislative
body (including a committee thereof) with jurisdiction to order Employee to divulge, disclose or make accessible such information.
“Confidential Information” shall mean non-public information concerning the financial data, strategic business plans,
product development (or other proprietary product data), customer lists, marketing plans and other non-public, proprietary and
confidential information of the Company or its affiliates (hereinafter referred to as the “Protected Group”) or the
Company's existing or potential customers. Confidential Information does not include information which: (i) becomes generally available
to the public, unless said Confidential Information was disclosed in violation of a confidentiality agreement; or (ii) becomes
available to Executive on a non-confidential basis from a source other than the Company or its agents, provided that such source
is not bound by a confidentiality agreement with the Company.

 

    	Page 7 of 14

    	 

    

 

6.           Restrictive
Covenants

 

(a)          Noncompete.
During the period of Employee’s employment hereunder and six (6) months thereafter (“Non-Competition Period”),
the Employee shall not, within any state or foreign jurisdiction in which the Company or any subsidiary of the Company is then
providing services or products or marketing its services or products (or engaged in active discussions to provide such services),
or within a 50-mile radius of any such state or foreign jurisdiction, directly or indirectly own any interest in, manage, control,
participate in, consult with, render services for, or in any manner engage in any Business Engaged In by the Company, as defined
herein, (unless the Board shall have authorized such activity and the Company shall have consented thereto in writing). The term
“Business Engaged In by the Company” shall mean any person or entity engaged in (i) the use of products or technology
similar to the Company’s platelet rich plasma platform technology, including the Angel® Whole Blood Separation System
and the AutoloGelTM System as well as the ALDH bright cell-based therapies, (ii) any use of products or technology competitive
with those which the Company is actively developing during the Term, or (iii) the direct competition with either (i) or (ii) above.
Investments in less than 5% of the outstanding securities of any class of a corporation subject to the reporting requirements of
Section 13 or Section 15(d) of the Securities Exchange Act of 1934, as amended, shall not be prohibited by this Section.

 

Employee and the Company
agree that this covenant not to compete is a reasonable covenant under the circumstances, and further agree that if in the opinion
of any court of competent jurisdiction such restraint is not reasonable in any respect, such court shall have the right, power
and authority to excise or modify such provision or provisions of this covenant as to the court shall appear not reasonable and
to enforce the remainder of the covenant as so modified. Employee agrees that any breach of the covenants contained in this Exhibit
A would irreparably injure the Company. Accordingly, Employee agrees that the Company may, in addition to pursuing any other remedies
it or they may have in law or in equity, cease making any payments otherwise required by this Agreement and obtain an injunction
against Employee from any court having jurisdiction over the matter restraining any further violation of this Agreement by Employee.

 

(b)          
Non-solicitation. Employee agrees that for the term of his employment with the Company and for the period of
six (6) months after the termination of Employee’s employment with the Company, he shall not, except with the prior written
consent of the Company signed by the CEO, solicit, any persons or entities who are members of the Company as of the date of this
Agreement or any persons or entities who hereafter become members of the Company.

 

    	Page 8 of 14

    	 

    

 

(c)          Non-Disparagement.
  Employee agrees that he will not, directly or indirectly, individually or in concert with others, engage in any conduct or make
any statement that is likely to have the effect of undermining or disparaging the reputation of the Company or any member of the
Protected Group, or their good will, products, or business opportunities, or that is likely to have the effect of undermining or
disparaging the reputation of any officer, director, agent, representative or employee, past or present, of the Company or any
member of the Protected Group. The Company agrees that it shall not, directly or indirectly, engage in any conduct or make any
statement that is likely to have the effect of undermining or disparaging the reputation of Employee. 

 

(d)          Notification
to New Employer. In the event that Employee leaves the employ of the Company, Employee hereby gives his consent to notification
by the Company to his new employer about Employee's obligations under this Agreement, including providing such new employer a copy
of this Agreement. The Company shall provide Employee a copy of such written notification (if any) given to Employee's new employer
pursuant to the immediately preceding sentence. Employee hereby agrees to provide (prior to his commencement of employment with
such new employer) any such new employer a copy of this Agreement.

 

(e)          Property
of the Company. Employee agrees that all records, files, memoranda, reports, client lists, programs, work product, or any other
similar records or documents relating to the Company's business (including without limitation those which may have been used or
prepared by Employee, whether or not part of the Confidential Information), remain the sole personal property of the Company and
remain at all times, both during and after Employee's employment with the Company, in the control of the Company. Employee hereby
waives and releases all claims of right of ownership thereto and Employee hereby agrees that upon the termination of his employment
with the Company for any reason whatsoever, Employee shall immediately surrender all such records and documents, and all copies
thereof, together with any other property of the Company in Employee's possession, to the Company at its principal business office
or such other location as directed by the Company.

 

7.           Dispute
Resolution.

 

All disputes between
the Parties arising from the construction or performance of, or otherwise in connection with this Agreement, shall be finally settled
in Maryland, before one arbitrator appointed by agreement between the parties pursuant to the rules of the American Arbitration
Association. If the parties cannot agree on an arbitrator then such arbitrator shall be appointed by the American Arbitration Association.
The arbitration procedure and all decisions made by the arbitrator shall be kept confidential, unless the Parties expressly consent
to the publication thereof in whole or in part. Unless oral hearings are requested by a party, the arbitrator shall make his/her
award on the basis of written submissions. In the event of any proceeding between the Company and the Employee with respect to
the subject matter of this Agreement and the enforcement of the rights hereunder and such proceeding results in final judgment
or order in favor of one of the Parties, which judgment or order is substantially inconsistent with the positions asserted by the
other Party in such litigation or proceeding, the losing Party in such event shall reimburse the prevailing Party for all of its
reasonable costs and expenses relating to such litigation or other proceeding, including, without limitation, its reasonable attorneys’
fees and expenses. Such payments shall be made no later than sixty (60) days after the final judgment or order is entered.

 

    	Page 9 of 14

    	 

    

 

8.           Consolidation;
Merger; Sale of Assets; Change of Control.

 

Nothing in this Agreement
shall preclude the Company from combining, consolidating or merging with or into, transferring all or substantially all of its
assets to, or entering into a partnership or joint venture with, another corporation or other entity, or effecting any other kind
of business combination provided that the entity resulting from or surviving such combination, consolidation or merger, or to which
such assets are transferred, or such partnership or joint venture, assumes this Agreement and all obligations and undertakings
of the Company hereunder. Upon such a consolidation, merger, transfer of assets or formation of such partnership or joint venture,
this Agreement shall inure to the benefit of, be assumed by, and be binding upon such resulting or surviving transferee corporation
or such partnership or joint venture, and the term “Company,” as used in this Agreement, shall mean such corporation,
partnership or joint venture or other entity, and this Agreement shall continue in full force and effect in accordance with its
terms and shall entitle the Employee and his heirs, beneficiaries and representatives to substantially the same compensation, benefits,
payments and other rights as would have been their entitlement had such combination, consolidation, merger, transfer of assets
or formation of such partnership or joint venture not occurred.

 

9.           Survival
of Obligations.

 

Sections 2(c), 2(e),
3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20 and 21 shall survive the termination for any reason of this Agreement
(whether such termination is by the Company, by the Employee, upon the expiration of this Agreement or otherwise).

 

10.         Employee’s
Representations.

 

The Employee hereby
represents and warrants to the Company that (i) the execution, delivery and performance of this Agreement by the Employee do not
and shall not materially conflict with, breach, violate or cause a default under any contract, agreement, instrument, order, judgment
or decree to which the Employee is a party or by which he is bound, (ii) the Employee is not a party to or bound by any employment
agreement, non-compete agreement or confidentiality agreement with any other person or entity and (iii) upon the execution and
delivery of this Agreement by the Company and the Employee, this Agreement shall be the valid and binding obligation of the Employee,
enforceable in accordance with its terms. The Employee hereby acknowledges and represents that he has consulted with legal counsel
regarding his rights and obligations under this Agreement and that he fully understands the terms and conditions contained herein.

 

11.         Company’s
Representations.

 

The Company hereby
represents and warrants to the Employee that (i) the execution, delivery and performance of this Agreement by the Company do not
and shall not materially conflict with, breach, violate or cause a default under any contract, agreement, instrument, order, judgment
or decree to which the Company is a party or by which it is bound and (ii) upon the execution and delivery of this Agreement by
the Employee and the Company, this Agreement shall be the valid and binding obligation of the Company, enforceable in accordance
with its terms.

 

    	Page 10 of 14

    	 

    

 

12.         Enforcement.

 

Because the Employee’s
services are unique and because the Employee has access to Confidential Information concerning the Company, the parties hereto
agree that money damages alone may not be an adequate remedy for any breach of this Agreement. In the event of a breach or threatened
breach of this Agreement, either party may, in addition to other rights and remedies existing in its favor, apply to any court
of competent jurisdiction in Maryland for injunctive relief in order to enforce, or prevent any violations of, the provisions hereof
(without posting a bond or other security).

 

13.         Severability.

 

In case any one or
more of the provisions or part(s) of provisions contained in this Agreement shall for any reason be held to be invalid, illegal
or unenforceable in any respect in any jurisdiction, such invalidity, illegality or unenforceability shall be deemed not to affect
any other jurisdiction or any other provision or part of a provision of this Agreement, nor shall such invalidity, illegality or
unenforceability affect the validity, legality or enforceability of this Agreement or any provision or provisions hereof in any
other jurisdiction; and this Agreement shall be reformed and construed in such jurisdiction as if such provision or part of a provision
held to be invalid or illegal or unenforceable had never been contained herein and such provision or part reformed so that it would
be valid, legal and enforceable in such jurisdiction to the maximum extent possible. If, in any judicial proceeding, a court shall
refuse to enforce any of such separate covenants, then such unenforceable covenants shall be deemed eliminated from the provisions
hereof for the purpose of such proceedings to the extent necessary to permit the remaining separate covenants to be enforced in
such proceedings. If, in any judicial proceeding, a court shall refuse to enforce any one or more of such separate covenants because
the total time, scope or area thereof is deemed to be excessive or unreasonable, then it is the intent of the parties hereto that
such covenants, which would otherwise be unenforceable due to such excessive or unreasonable period of time, scope or area, be
enforced for such lesser period of time, scope or area as shall be deemed reasonable and not excessive by such court.

 

14.         Entire
Agreement; Amendment; Indemnification; Fees.

 

(a)          Entire
Agreement. Except as otherwise set forth in this Agreement, this Agreement contains the entire agreement between the Company
and the Employee with respect to the subject matter hereof and thereof and supersedes and nullifies all previous agreements between
the parties about the Company’s employment of the Employee. This Agreement may not be amended, waived, changed, modified
or discharged except by an instrument in writing executed by or on behalf of the party against whom enforcement of any amendment,
waiver, change, modification or discharge is sought. No course of conduct or dealing shall be construed to modify, amend or otherwise
affect any of the provisions hereof.

 

    	Page 11 of 14

    	 

    

 

(b)          Indemnification.
The Company shall enter into an Indemnification Agreement with Employee that is customary for an executive officer of a public
reporting company and in the same form as provided to the members of the Board of Directors.

 

(c)          Reimbursement.
The Company will reimburse Employee an amount not to exceed $7,500 for legal fees relating to the review of this Agreement by counsel
on behalf of Employee.

 

15.         Notices.

 

All notices, requests,
demands and other communications hereunder shall be in writing and shall be deemed to have been duly given if physically delivered,
delivered by overnight mail or other expedited service and contains tracking information to show delivery or upon receipt if mailed,
postage prepaid, via registered mail, return receipt requested, addressed as follows:

 

	(a)	To the Company:	(b)	To the Employee:
	 	 	 	 
	 	Cytomedix, Inc.	 	Dean Tozer
	 	209 Perry Parkway, Suite 7	 	 
	 	Gaithersburg, MD 20877	 	 
	 	Attn: Chairman of the Compensation Committee	 	 
	 	 	 	 
	 	and to:	 	and to:
	 	 	 	 
	 	Alec Orudjev, Esq.	Kolin B. Holladay, Esq.
	 	Schiff Hardin LLP	Adams and Reese LLP
	 	901 K Street, NW, Suite 700	424 Church Street, Suite 2700
	 	 	 	 
	 	Washington, DC 20001	Nashville, Tennessee 37219

 

and/or to such other
persons and addresses as any party shall have specified in writing to the other.

 

16.         Assignability.

 

This Agreement shall
be assignable by the Company but not the Employee, and shall be binding upon, and shall inure to the benefit of, the heirs, executors,
administrators, legal representatives, successors and permitted assigns of the parties. This Agreement shall inure to the benefit
of and be enforceable by the Employee’s personal or legal representatives, executors, administrators, successors, heirs,
distributees, devisees and legatees.

 

    	Page 12 of 14

    	 

    

 

17.         Governing
Law.

 

This Agreement shall
be governed by and construed under the laws of the State of Delaware.

 

18.         Waiver
and Further Agreement.

 

Any waiver of any breach
of any terms or conditions of this Agreement shall not operate as a waiver of any other breach of such terms or conditions or any
other term or condition, nor shall any failure to enforce any provision hereof operate as a waiver of such provision or of any
other provision hereof. Each of the parties hereto agrees to execute all such further instruments and documents and to take all
such further action as the other party may reasonably require in order to effectuate the terms and purposes of this Agreement.

 

19.         Headings
of No Effect.

 

The paragraph headings
contained in this Agreement are for reference purposes only and shall not in any way affect the meaning or interpretation of this
Agreement.

 

20.         Section
409A of the Internal Revenue Code.

 

Each payment under
this Agreement is intended to be exempt from Section 409A of the Internal Revenue Code of 1986, as amended (the “Code”)
or in compliance with Code Section 409A, and the provisions of this Agreement will be administered, interpreted and construed accordingly.
Without limiting the generality of the foregoing, the term “termination of employment” or any similar term under this
Agreement will be interpreted to mean “separation from service” within the meaning of Code Section 409A to the extent
necessary to comply with Code Section 409A. Furthermore, the right to a series of installment payments or in-kind benefits under
this Agreement is to be treated as a right to a series of separate payments for purposes of Code Section 409A.

 

Notwithstanding anything
in this Agreement to the contrary, for any year in which the stock of the Company is tradable on an established securities market,
and the Employee meets the requirements of Code Section 416(i)(1)(A)(i), (ii), or (iii) (applied in accordance with the regulations
thereunder, but without regard to Code Section 416(i)(5)) at any time during the 12 month period ending on the last occurring December 31st
(and is therefore a “Specified Employee”), then, to the extent required by Code Section 409A, and the final regulations
thereunder, the Company shall pay any benefit which constitutes “deferred compensation” under this Agreement within
the meaning of the Code Section 409A no earlier than the earliest of the following:

 

		(1)	the expiration of the six month period (the “Deferral Period”) measured from the date
of the Employee’s ‘separation from service’ under Code Section 409A; or

 

		(2)	the date of the Employee’s death.

 

    	Page 13 of 14

    	 

    

 

Upon the expiration
of the Deferral Period, all payments that would have been made during the Deferral Period (whether in a single lump sum or in installments)
shall be paid as a single lump sum to the Employee or, if applicable, his or her beneficiary. This section shall not apply to any
payment which constitutes “separation pay” as described in Treasury Regulation 1.409A-1(b)(9)(iii).

 

To the extent required
by Code Section 409A, with regard to any provision that provides for the reimbursement of costs and expenses, or for the provision
of in-kind benefits:

 

		(1)	The right to such reimbursement or in-kind benefit shall not be subject to liquidation or exchange
for another benefit;

 

		(2)	The amount of expenses or in kind benefits available or paid in one year shall not affect the amount
available or paid in any subsequent year; and

 

		(3)	Such payments shall be made on or before the last day of the Employee’s taxable year following
the taxable year in which the expense occurred.

 

21.         Code
Section 280G

 

Notwithstanding anything
contained in this Agreement to the contrary, to the extent that any of the payments and benefits provided for under this Agreement,
together with any payments or benefits under any other agreement or arrangement between the Company or any of their subsidiaries
or affiliates and Employee (collectively, the “Payments”) would constitute a “parachute payment” within
the meaning of Section 280G of the Code, Employee shall receive total payments equal to the greater, after the application of the
excise tax imposed pursuant to Section 4999 of the Code, of the Payments provided under this Agreement or the amount of such Payments
reduced to the greatest amount that would result in no portion of the Payments being subject to such excise tax.

 

IN WITNESS WHEREOF,
the parties hereto have executed this Employment Agreement as of the date first above written.

 

	 	COMPANY:
	 	 
	 	CYTOMEDIX, INC.

 

	 	By:	/s/ Martin Rosendale	 
	 	 	Martin Rosendale	 
	 	 	Chief Executive Officer	 
	 	 	 	 
	 	 	EMPLOYEE:	 
	 	 	 	 
	 	 	/s/ Dean Tozer	 
	 	 	Dean Tozer	 

 

    	Page 14 of 14

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