Document:

Exhibit 4.23

                              EMPLOYMENT AGREEMENT

         THIS AGREEMENT, made and entered into as of January 7, 2005, provided
the employment hereunder shall commence on January 31, 2005, or other mutually
convenient date, by and among Radica Enterprises Ltd., a Nevada corporation,
having an office at 13628-A Beta Road, Dallas, Texas 75244, Radica Games
Limited, a Bermuda company, having an office at Suite V, 6/F, 2-12 Au Pui Wan
Street, Fo Tan, Hong Kong, and Theodore J. Eischeid, who resides at 78 Quail
Drive, Lake Forest, IL 60045.

         WHEREAS, Radica is engaged through its subsidiaries in designing and
manufacturing games and youth electronics and VGA products and accessories, and
OEM manufacturing for others;

         WHEREAS, Radica USA is engaged in marketing and distributing products
manufactured by Radica;

         WHEREAS, Employee has substantial executive management experience
including marketing experience in the United States;

         WHEREAS, Radica USA and Radica desire to secure the services of
Employee, and Employee is willing to provide such services, each upon the terms
and subject to the conditions set forth in this Agreement.

         NOW, THEREFORE, in consideration of the premises, the parties agree as
follows:

1.   DEFINITIONS. For the purposes of this Agreement, the parties hereby adopt
     the following definitions:

     a)   "Cause" means:

          i)   breach by Employee of a fiduciary obligation to any member of
               Radica Group;

          ii)  intentional commission by Employee of any act or omission to
               perform any act (excluding the omission to perform any act
               attributable to Employee's Total Disability) which results in
               material adverse consequences to any member of Radica Group;

          iii) material breach of any of Employee's agreements set forth in this
               Agreement including, but not limited to, continual failure to
               perform substantially his duties with Radica Group after
               notification of same, excessive absenteeism and dishonesty;

          iv)  any attempt by Employee to assign or delegate this Agreement or
               any of the rights, duties, responsibilities, privileges or
               obligations hereunder without the prior written consent of Radica
               or Radica USA

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               (except in respect of any delegation by Employee of his
               employment duties hereunder to other employees of Radica Group in
               accordance with its usual business practice);

           v)  Employee's arrest or indictment for, or written confession of, a
               felony or any crime involving moral turpitude under the laws of
               the United States or any state or of Hong Kong;

          vi)  death of Employee;

         vii) declaration by a court that Employee is insane or incompetent to
               manage his business affairs; or

         viii) the filing of any petition or other proceeding seeking to find
               Employee bankrupt or insolvent.

     b)   "Change in Control" means the occurrence of any one of the following
          events:

          (i)  individuals who, on January 1, 2005, constitute the Board (the
               "Incumbent Directors") cease for any reason to constitute at
               least a majority of the Board, provided that any person becoming
               a director subsequent to January 1, 2005, whose election or
               nomination for election was approved by a vote of at least
               two-thirds of the Incumbent Directors then on the Board (either
               by a specific vote or by approval of the proxy statement of
               Radica in which such person is named as a nominee for director,
               without written objection to such nomination) shall be an
               Incumbent Director; provided, however, that no individual
               initially elected or nominated as a director of Radica as a
               result of an actual or threatened election contest with respect
               to directors or as a result of any other actual or threatened
               solicitation of proxies or consents by or on behalf of any person
               other than the Board shall be deemed to be an Incumbent Director;

          (ii) any "person" (as such term is defined in Section 3(a)(9) of the
               Securities Exchange Act of 1934, as amended (the "Exchange Act")
               and as used in Sections 13(d)(3) and 14(d)(2) of the Exchange
               Act) becomes a "beneficial owner" (as defined in Rule 13d3 under
               the Exchange Act), directly or indirectly, of securities of
               Radica representing 50% or more of the combined voting power of
               Radica's then outstanding securities eligible to vote for the
               election of the Board (the "Radica Voting Securities") or any
               person who beneficially owns 50% of the Radica Voting Securities
               increases their beneficial ownership by more than 5%; provided,
               however, that the event described in this paragraph (ii) shall
               not be deemed to be a Change in Control by virtue of any of the
               following acquisitions: (A) by Radica or any member of the Radica
               Group, (B) by any employee benefit plan (or related trust)
               sponsored or maintained by Radica or any member of the Radica
               Group, (C) by any underwriter temporarily holding securities
               pursuant to an offering of such securities, (D) pursuant to a
               Non-Qualifying Transaction (as defined in

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               paragraph (iii)), or (E) pursuant to any acquisition by Employee
               or any group of persons including Employee (or any entity
               controlled by Employee or any group of persons including
               Employee);

         (iii) the consummation of a merger, consolidation, statutory share
               exchange or similar form of corporate transaction involving
               Radica or any member of the Radica Group that requires the
               approval of Radica's stockholders, whether for such transaction
               or the issuance of securities in the transaction (a "Business
               Combination"), unless immediately following such Business
               Combination: (A) more than 50% of the total voting power of (x)
               the corporation resulting from such Business Combination (the
               "Surviving Corporation"), or (y) if applicable, the ultimate
               parent corporation that directly or indirectly has beneficial
               ownership of at least 95% of the voting securities eligible to
               elect directors of the Surviving Corporation (the "Parent
               Corporation"), is represented by Radica Voting Securities that
               were outstanding immediately prior to such Business Combination
               (or, if applicable, is represented by shares into which such
               Radica Voting Securities were converted pursuant to such Business
               Combination), and such voting power among the holders thereof is
               in substantially the same proportion as the voting power of such
               Radica Voting Securities among the holders thereof immediately
               prior to the Business Combination, (B) no person (other than any
               employee benefit plan (or related trust) sponsored or maintained
               by the Surviving Corporation or the Parent Corporation or an
               existing Radica shareholder, with greater than 50% beneficial
               ownership of the Radica Voting Securities prior to the Business
               Combination, whose percentage beneficial ownership compared to
               the other Radica shareholders in existence immediately prior to
               the Business Combination does not change on consummation of the
               Business Transaction), is or becomes the beneficial owner,
               directly or indirectly, of 50% or more of the total voting power
               of the outstanding voting securities eligible to elect directors
               of the Parent Corporation (or, if there is no Parent Corporation,
               the Surviving Corporation) and (C) at least a majority of the
               members of the board of directors of the Parent Corporation (or,
               if there is no Parent Corporation, the Surviving Corporation)
               following the consummation of the Business Combination were
               Incumbent Directors at the time of the Board's approval of the
               execution of the initial agreement providing for such Business
               Combination (any Business Combination which satisfies all of the
               criteria specified in (A), (B) and (C) above shall be deemed to
               be a "Non-Qualifying Transaction"); or

          (iv) the stockholders of Radica approve a plan of complete liquidation
               or dissolution of Radica or the consummation of a sale of all or
               substantially all of Radica's assets.

          Notwithstanding the foregoing, a Change in Control of Radica shall not
          be deemed to occur solely because any person acquires beneficial
          ownership of more than 50% of the Radica Voting Securities as a
          result of the acquisition of Radica Voting Securities

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<PAGE>

          by Radica which reduces the number of Radica Voting Securities
          outstanding; provided, that if after such acquisition by Radica such
          person becomes the beneficial owner of additional Radica Voting
          Securities that increases the percentage of outstanding Radica Voting
          Securities beneficially owned by such person, a Change in Control of
          Radica shall then occur.

     c)   "Dollars" and "US$" means United States dollars.

     d)   "Employee" means Theodore J. Eischeid.

     e)   "Good Reason" shall mean the occurrence within twelve months after a
          Change in Control of any of the following events without the
          Employee's express written consent: (i) the assignment to the Employee
          of duties inconsistent with his position and status as an executive of
          the Radica Group, or a substantial alteration in the nature, status or
          prestige of the Employee's responsibilities with the Radica Group from
          those in effect immediately prior to such Change in Control; or (ii) a
          reduction in the Employee's base salary or bonus at the rate most
          recently approved by the Board prior to the occurrence of such Change
          in Control; or (iii) any other material adverse change in the terms or
          conditions, including location and travel, of the Employee's
          employment hereunder following the occurrence of such Change in
          Control. Notwithstanding the foregoing, if Employee does not deliver
          to Radica and Radica USA a notice of termination within 90 days after
          the occurrence of the event constituting Good Reason has occurred, the
          event will no longer constitute Good Reason. An isolated,
          insubstantial and inadvertent action taken in good faith and which is
          remedied by Radica or Radica USA within 10 days after receipt of
          notice thereof given by Employee shall not constitute Good Reason.

     f)   "Omnibus Plan" means the 2004 omnibus equity incentive plan adopted by
          Radica, as amended from time to time.

     g)   "Radica" means Radica Games Limited, a Bermuda company.

     h)   "Radica Group" means Radica, Radica USA and any other corporation or
          other entity which at the relevant time is more than fifty percent
          (50%) owned, directly or indirectly, by Radica.

     i)   "Radica USA" means Radica Enterprises Ltd., a Nevada corporation.

     j)   "Termination" means, according to the context, the termination of this
          Agreement or the cessation of rendering employment services by
          Employee.

     k)   "Total Disability" means Employee shall become disabled to an extent
          which renders him unable to perform the essential functions of his
          employment hereunder, with or without reasonable accommodation, for a
          cumulative period of twelve (12) weeks in any twelve (12) month
          period.

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2.   EMPLOYMENT.

     a)   Commencing on the date referred to in the first paragraph of this
          Agreement, Radica hereby employs Employee and Employee hereby accepts
          employment by Radica to serve as the President and Chief Operating
          Officer of Radica, and to report to the Chief Executive Officer of
          Radica. During his period of employment, employee also agrees to serve
          as a member of the board of directors of Radica, Radica USA and of
          such other members of Radica Group as may be determined by the Board
          of Directors of Radica ("Board"). Employee shall perform services of
          an executive nature consistent with his offices with Radica and Radica
          USA and as a director of Radica as may from time to time be assigned
          or delegated to him by the Board.

     b)   Employee will devote his full business time and attention to his
          duties under this Agreement. However, Employee can, with the consent
          of Radica which shall not be unreasonably withheld, join the Board of
          Directors of other companies and to contribute a reasonable amount of
          time to philanthropic activities.

     c)   Employee shall perform his duties under this Agreement principally in
          or around Dallas, Texas. It is contemplated Employee will frequently
          travel to carry out his duties under this Agreement, including travel
          to the other offices of the Radica Group. Air travel and other travel
          arrangements will comply with current Radica Group policies respecting
          class of travel, etc.

     d)   Radica Group will provide to Employee, his spouse and children medical
          benefits which are provided to other officers of Radica USA, Ltd. In
          the event Employee is required to elect COBRA coverage as a result of
          any pre-existing medical condition, Radica will pay Employee an amount
          which, net of applicable tax, will reimburse the cost of such COBRA
          coverage.

     e)   Employee shall have four (4) weeks paid vacation during each year of
          this Agreement taken at such times as mutually convenient to Employee
          and Radica Group.

3.   TERM OF EMPLOYMENT.

     a)   This Agreement and Employee's employment hereunder shall commence on
          the date referred to in the first paragraph of this Agreement, and
          continue until January 31, 2007, and shall be extended annually at
          each January 31 (commencing January 31, 2006) for an additional one
          year period so that the term hereof after each January 31 shall be a
          two year period, unless a party to this Agreement gives notice at
          least ninety (90) days prior to January 31 that this Agreement shall
          not be renewed, in which case this Agreement shall terminate at the
          end of the then current term.

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     b)   Notwithstanding Paragraph (a) above, this Agreement may be sooner
          terminated by Radica or Radica USA for Cause, by Employee without
          consent of Radica or Radica USA, by Radica or Radica USA without
          Cause, or by Radica or Radica USA in the event of the Total Disability
          of Employee. This Agreement may also be sooner terminated by Employee
          following any Change in Control and if following such Change in
          Control Employee has Good Reason for such Termination; such
          Termination by Employee is herein called a "Termination/Change in
          Control".

     c)   On termination of this Agreement pursuant to Paragraph (a) above, or
          by Radica or Radica USA for Cause, or by Employee without consent of
          Radica or Radica USA, all benefits and compensation shall cease as of
          the date of such Termination. On termination of this Agreement by
          Radica or Radica USA without Cause or by Employee for Good Reason in
          the event of a Termination/Change in Control or in the event of Total
          Disability of Employee, (i) Radica USA will continue to pay Employee
          his annual salary for twelve months from the date of Termination, (ii)
          Radica Group will continue to provide medical and dental benefits to
          Employee for twelve months from the date of Termination on the same
          basis and at the same Employee cost as at the date of Termination and
          (iii) Employee's stock options, restricted stock, and restricted stock
          units will be treated as set forth in Section 6 hereof.

4.   BUSINESS EXPENSE REIMBURSEMENT. Employee will be entitled to reimbursement
     by Radica Group for the reasonable business expenses paid by him on behalf
     of Radica Group in the course of his employment hereunder on presentation
     to Radica Group of appropriate vouchers (accompanied by receipts or paid
     bills) setting forth information sufficient to establish:

               i)   the amount, date, and place of each such expense;

               ii)  the business reason for each such expense and the nature of
                    the business benefit derived or expected to be derived as a
                    result thereof; and

               iii) the names, occupations, addresses, and other information
                    sufficient to establish the business relationship to Radica
                    Group of any person who was entertained by Employee.

5.   COMPENSATION. Radica USA agrees to pay Employee, and Employee agrees to
     accept from Radica USA, during the first year after commencement of
     employment, for the services to be rendered by him hereunder a minimum
     salary at the rate of US$315,000 per annum payable in arrears in bi-weekly
     installments. Employee shall receive annual salary reviews by the Board
     provided that such salary shall not be reduced below US$315,000 per year.
     After a Change in Control, Employee's salary

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     shall not be reduced below the level immediately prior to the Change in
     Control. Employee shall also be entitled to relocation payments as detailed
     below.

     If Radica Group institutes a retirement, bonus or other benefit plan which
     applies generally to U.S. executive officers of Radica Group, Employee
     shall be entitled to participate therein, but not to the extent such
     benefits would be duplicative of the benefits herein. Employee shall
     participate in the Radica incentive compensation plan for executive
     officers as in place from time to time and shall participate at the same
     percentage level as the chief executive officer (i.e., in 2005 the target
     bonus percentage of salary is 80% for meeting performance targets with a
     potential of 120% of base salary for exceeding performance targets). Such
     target bonus percentage will be applied to Employee's annual base salary
     without proration for 2005 based upon commencement of employment.
     Specifically, the calculation methodology and incentive percentages shall
     be the same as those of the CEO but the performance target criteria is to
     be determined by the Board with the majority of the criteria being the
     operating income of the Company.

     Employee agrees that he shall have a residence in the Dallas, Texas area
     within 90 days of employment. Radica USA agrees to pay Employee a lump sum
     relocation amount of $75,000 related thereto in six equal monthly
     installments beginning on the date of initial employment. During the first
     90 days of employment, Employee's work location will be his home in Lake
     Forest, Illinois. All payments and other compensation to Employee shall be
     subject to applicable withholdings.

6.   STOCK OPTIONS AND RESTRICTED STOCK.

     a)   i)   Within the first 90 days of commencement of employment, as of a
               date determined by Employee, (the "Grant Date"), Radica hereby
               grants to Employee an option to purchase sixty thousand (60,000)
               shares of the common stock of Radica at the closing market price
               per share on the Grant Date subject to the terms and conditions
               of this Section 6 and the Omnibus Plan (the "Stock Option").

          ii)  As of the date of commencement of employment (the "Grant Date"),
               pursuant to the Omnibus Plan, Radica hereby grants to Employee a
               restricted stock award of 25,000 shares of Radica common stock
               (the "Restricted Stock") which shall vest on March 31, 2008 and
               shall be forfeited if the employment of Employee shall be
               terminated, for any reason other than as provided in Section
               6(c), prior to such date. In addition, should termination of
               employment with Employee's current employer, in order to be
               employed by the Radica Group, cause the loss of the Employee's
               2004 bonus from his current employer, the vesting of the
               restricted stock shall be immediate for the market value of 60%
               of the lost bonus, and 40% of the value of the lost bonus shall
               be paid in cash, with reasonable promptness after it is
               ascertained that the bonus has been lost, and an amount of the
               above Restricted Stock

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               award equal to the cash payment shall be cancelled. In no event
               shall any amount of the lost bonus, for this purpose, exceed the
               market value of the 25,000 shares of Restricted Stock, to be
               measured based on the closing stock price on the Grant Date. The
               amount of the lost bonus must be documented by Employee and
               Radica agrees to work with Employee and Employee's current
               employer to determine a transition plan that minimizes the amount
               of any lost bonus while satisfying Radica's needs for Employee to
               begin employment as close as possible to January 31, 2005.

          iii) Subject to the other provisions of this Section 6, the Stock
               Options shall vest and become exercisable 33?% per year following
               the Grant Date, commencing at the first anniversary of the Grant
               Date.

     b)   The number of shares subject to the Stock Options or the Restricted
          Stock will be adjusted for stock splits and reverse splits; provided
          that such number of shares shall not be adjusted if Radica should
          otherwise change or modify its capitalization, including but not
          limited to the issuance by Radica of new securities (including options
          or convertible securities), ESOP's or other employee stock plans. It
          is the intent of the parties that the stock subject to the Stock
          Options or the Restricted Stock shall be subject to dilution, except
          for stock splits and reverse splits.

     c)   (i)  As of the date of Termination in the event of Termination
               pursuant to Section 3(a) or Termination by Radica or Radica USA
               for Cause or by Employee without consent of Radica or Radica USA,
               or (ii) twelve (12) months after the date of Termination in the
               event of Termination by Radica or Radica USA without Cause or by
               Employee for Good Reason in the event of a Termination/Change in
               Control (unless Section 6(f) of this Agreement applies, in which
               case this Section 6(c) shall not apply to Employee's Stock
               Options, restricted stock and restricted stock units) or the
               Total Disability of Employee (each of such applicable dates being
               called a "Determination Date"), Employee shall forfeit the Stock
               Options (measured by percentages of the stock subject to the
               Stock Options) and they shall expire as follows:

               (A)  if the Determination Date is within the first year after the
                    date the Stock Option is granted (the "Grant Date") then
                    Employee shall forfeit 100% of the stock subject to the
                    Stock Option;

               (B)  if the Determination Date is after the end of said first
                    year and within the second year after the Grant Date, then
                    Employee shall forfeit 66?% of the stock subject to the
                    Stock Option; or

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               (C)  if the Determination Date is after the end of said second
                    year and within the third year after the Grant Date, then
                    Employee shall forfeit 33?% of the stock subject to the
                    Stock Option.

          And Employee shall forfeit the Restricted Stock and it shall expire as
          follows:

               (D)  if the Determination Date is prior to March 31, 2008, then
                    Employee shall forfeit 100% of such Restricted Stock.

     d)   In any event each Stock Option shall expire to the extent not
          previously exercised on the tenth anniversary of the Grant Date.
          Otherwise, Employee may at any time within ninety (90) days following
          the Determination Date, exercise his right to purchase stock subject
          to the Stock Options, but subject to the foregoing provisions
          respecting vesting and forfeitures. Restricted Stock, and restricted
          stock units, if not forfeited, shall be deliverable to Employee upon
          its applicable vesting date, free of the previously existing
          restrictions, but subject to applicable state and federal securities
          laws.

     e)   Employee shall have no right to sell, alienate, mortgage, pledge, gift
          or otherwise transfer the Stock Options, the Restricted Stock or any
          restricted stock units or any rights thereto, except by will or by the
          laws of descent and distribution, and except pursuant to applicable
          state and federal securities laws and except as specifically
          contemplated herein.

     f)   Upon the occurrence of a Change in Control under the Omnibus Plan, all
          of Employee's then outstanding stock options, restricted stock, and
          restricted stock units in Radica shall vest and become immediately
          exercisable. If Employee is terminated by Radica or Radica USA without
          Cause after a definitive agreement for a transaction that would
          constitute a Change in Control as described in the Omnibus Plan has
          been approved by the shareholders of Radica, but before such
          transaction is consummated, Employee's stock options shall vest on the
          date of such termination without Cause. Income realized by Employee as
          a result of the acceleration of vesting of equity compensation or
          otherwise resulting from a Termination/Change in Control is
          specifically paid in consideration of post-employment restrictions of
          Section 7 hereunder.

7.   NON-COMPETE; CONFIDENTIALITY.

     a)   During the term of employment of Employee, and for a period of one
          year ("Prohibition Period") after any Termination (other than in the
          event of a Termination/Change in Control) of such relationship or
          employment for any other reason (either by Employee or Radica or
          Radica USA), with or without cause, voluntarily or involuntarily,
          Employee agrees that he will not engage in, be employed by or become
          affiliated with, in the United States of America or anywhere else in
          the world, directly or indirectly, any person or entity which offers,
          develops, performs or is engaged in services, products or

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          systems which are competitive with the business of Radica Group or any
          other products, services or systems hereafter developed, produced or
          offered by Radica Group ("Companies' Business"). During the
          Prohibition Period, Employee shall not, directly or indirectly, become
          an owner or member, to the extent of an ownership interest of five
          percent (5%) or more, of a joint venture, partnership, corporation or
          other entity, or a consultant, employee, agent, officer or director of
          a corporation, joint venture, partnership or other entity, which is
          competitive with, directly or indirectly, the Companies' Business.

     b)   [RESERVED.]

     c)   Employee understands and agrees that he has been exposed to (or had
          access to), and may be further exposed to (or have access to),
          confidential information, knowhow, knowledge, data, techniques,
          computer software and hardware, and trade secrets of Radica Group or
          related to the Companies' Business, including, without limitation,
          customer or supplier requirements, notes, drawings, writings, designs,
          plans, specifications, records, charts, methods, procedures, systems,
          price lists, financial data, records, and customer or supplier lists
          (collectively "Confidential Information"). Accordingly, except as
          permitted or required in the performance of his duties for Radica
          Group, Employee agrees not to disclose, divulge, make public, utilize,
          communicate or use, whether for his own benefit or for the benefit of
          others, either directly or indirectly, any Confidential Information
          relating to the Companies's Business unless specifically authorized in
          writing by Radica or Radica USA to do so.

     d)   Employee shall promptly communicate and disclose to Radica Group all
          information, inventions, improvements, discoveries, knowhow, methods,
          techniques, processes, observations and data ("Proprietary
          Information") obtained, developed, invented or otherwise discovered by
          him in the course of this employment. All written materials, records,
          computer programs or data and documents made by Employee or coming
          into his possession during the employment period concerning any
          Proprietary Information used or developed by Radica Group, or by
          Employee, shall be the sole exclusive property of Radica Group.
          Employee shall have no right, title or interest therein
          notwithstanding that he may have purchased the medium on which such
          Proprietary Information is recorded.

     e)   Upon Termination, Employee shall not take with him any of the
          Confidential Information or Proprietary Information. Upon Termination,
          or at any time upon the request of Radica or Radica USA, Employee
          shall promptly deliver all Confidential Information and Proprietary
          information, and all copies thereof, to Radica Group with no cost or
          charge to Radica Group. Upon request by Radica or Radica USA, Employee
          shall promptly execute and deliver any documents necessary or
          convenient to evidence ownership of the

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          Confidential Information and Proprietary Information by Radica Group,
          or the transfer and assignment of the Confidential Information and
          Proprietary Information to Radica Group without cost or charge. The
          provisions of this Section 7 shall survive any Termination of this
          Agreement.

8.   BENEFIT AND BINDING EFFECT. This Agreement shall inure to the benefit of
     and be binding upon Radica and Radica USA, their successors and assigns,
     including but not limited to any corporation, person or other entity which
     may acquire all or substantially all of the assets and business of Radica
     or Radica USA or any corporation with or into which they may be
     consolidated or merged. Radica and Radica USA may assign their rights and
     obligations to another present or future member of Radica Group. The rights
     and obligations of Employee hereunder may not be delegated or assigned.

9.   COUNTERPARTS. This Agreement may be executed in counterparts, each of which
     shall be deemed an original but all of which shall constitute one and the
     same instrument.

10.  GOVERNING LAW. THIS AGREEMENT SHALL BE GOVERNED BY AND CONSTRUED IN
     ACCORDANCE WITH THE LAW OF THE STATE OF NEVADA WITHOUT REFERENCE TO THE
     CHOICE OF LAW PRINCIPLES THEREOF.

11.  ENTIRE AGREEMENT. This Agreement sets forth and is an integration of all of
     the promises, agreements, conditions and understandings among the parties
     hereto with respect to all matters contained or referred to herein, and all
     prior promises, agreements, conditions, understandings, warranties or
     representations, oral, written, express or implied, are hereby superseded
     and merged herein.

12.  VALIDITY OF PROVISIONS. Should any provision(s) of this Agreement be void
     or unenforceable in whole or in part, the remainder of this Agreement shall
     not in any way be affected thereby, and such provision(s) shall be modified
     or amended so as to provide for the accomplishment of the provision(s) and
     intentions of this Agreement to the maximum extent possible.

13.  MODIFICATIONS OR DISCHARGE. This Agreement shall not be deemed waived,
     changed, modified, discharged or terminated in whole or in part, except as
     expressly provided for herein or by written instrument signed by all
     parties hereto. Each party agrees to make any modifications to this
     Agreement, including changing the timing of payments hereunder, as may be
     reasonably necessary to comply with Section 409A of the Internal Revenue
     Code.

14.  NOTICES. Any notice which either party may wish to give to the other
     parties hereunder shall be deemed to have been given when actually received
     by the party to whom it is addressed. Notices by Employee to either Radica
     or Radica USA shall be sent to both of them. Notices hereunder may be sent
     by courier, mail, telefax,

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     telegram or telex, to the following addresses, or to such other addresses
     as the parties may from time to time furnish to each other by like notice:

                 To: Radica Enterprises Ltd.
                     180 S. Lake Avenue, Suite 440
                     Pasadena, California 91101
                     U.S.A.
                     Attention: Patrick Feely
                     Telephone: (626) 744-1150
                     Telefax:   (626) 744-1155

                 To: Radica Games Limited
                     Suite R, 6/F
                     2-12 Au Pui Wan Street
                     Fo Tan
                     Hong Kong
                     Attention: David C.W. Howell
                     Telephone: (852) 2693 2238
                     Telefax:   (852) 2695 9657

                 To: Employee:
                      Theodore J. Eischeid
                      78 Quail Drive
                      Lake Forest, Illinois 60045
                      Telephone: (847) 295-0737

15.  NUMBER; GENDER. In this Agreement, the masculine shall include the feminine
     and neuter and vice versa, and the singular shall include the plural and
     vice versa, as the context may reasonably require or permit.

16.  REIMBURSEMENT OF EXPENSES. After a Change in Control or a Termination for
     Cause later determined to be a Termination Without Cause, if any dispute
     shall arise under this Agreement involving termination of Employee's
     employment with Radica or Radica USA or involving the failure or refusal of
     Radica or Radica USA to perform fully in accordance with the terms hereof,
     Radica or Radica USA shall reimburse Employee, on a current basis, for all
     reasonable legal fees and expenses, if any, incurred by Employee in
     connection with such contest or dispute (regardless of the result thereof),
     regardless of whether Employee's claim is upheld by a court of competent
     jurisdiction; provided, however, Employee shall be required to repay any
     such amounts to the Company to the extent that a court issues a final and
     non-appealable order setting forth the determination that the position
     taken by Employee was frivolous or advanced by Employee in bad faith.

                                      -12-
<PAGE>

         IN WITNESS WHEREOF, the parties have executed this Agreement as of the
day and year first above written.

                                        RADICA ENTERPRISES LTD.

                                        By:  /s/ Patrick S. Feely
                                           -------------------------------------

                                        RADICA GAMES LIMITED

                                        By:  /s/ Patrick S. Feely
                                           -------------------------------------

                                        Theodore J. Eischeid

                                             /s/ Theodore J. Eischeid
                                        ----------------------------------------

                                      -13-<PAGE>

                                                                    EXHIBIT 10.1

================================================================================

                            ASSET PURCHASE AGREEMENT

                                 BY AND BETWEEN

                                  CYGNUS, INC.,

                               ANIMAS CORPORATION

                                       AND

                             ANIMAS TECHNOLOGIES LLC

================================================================================

                               DECEMBER 16, 2004

<PAGE>

                                TABLE OF CONTENTS

<TABLE>
<CAPTION>
                                                                                                                Page
                                                                                                                ----
<S>                                                                                                              <C>
ARTICLE 1 DEFINITIONS..........................................................................................

   SECTION 1.01.        DEFINITIONS............................................................................
   SECTION 1.02.        INTERPRETATION AND RULES OF CONSTRUCTION...............................................

ARTICLE 2 PURCHASE AND SALE OF ASSETS..........................................................................

   SECTION 2.01.        PURCHASE AND SALE OF ASSETS............................................................
   SECTION 2.02.        EXCLUDED ASSETS........................................................................
   SECTION 2.03.        LIABILITIES............................................................................
   SECTION 2.04.        CONSIDERATION; CASH PAYMENTS AT CLOSING................................................
   SECTION 2.05.        THE CLOSING............................................................................
   SECTION 2.06.        GUARANTY OF PARENT.....................................................................

ARTICLE 3 REPRESENTATIONS AND WARRANTIES OF SELLER.............................................................

   SECTION 3.01.        ORGANIZATION...........................................................................
   SECTION 3.02.        SELLER ACTION..........................................................................
   SECTION 3.03.        CAPITAL STOCK..........................................................................
   SECTION 3.04.        COMPLIANCE WITH LAW....................................................................
   SECTION 3.05.        FDA AND OTHER REGULATORY COMPLIANCE....................................................
   SECTION 3.06.        SEC FILINGS............................................................................
   SECTION 3.07.        IMPORT/EXPORT LAWS.....................................................................
   SECTION 3.08.        ASSETS.................................................................................
   SECTION 3.09.        PERMITS................................................................................
   SECTION 3.10.        LIABILITIES............................................................................
   SECTION 3.11.        PRODUCTS LIABILITY.....................................................................
   SECTION 3.12.        PRODUCT WARRANTY.......................................................................
   SECTION 3.13.        OPERATIONS SINCE DECEMBER 31, 2003.....................................................
   SECTION 3.14.        REAL PROPERTY..........................................................................
   SECTION 3.15.        ENVIRONMENTAL..........................................................................
   SECTION 3.16.        INTELLECTUAL PROPERTY..................................................................
   SECTION 3.17.        CONTRACTS..............................................................................
   SECTION 3.18.        EMPLOYEES..............................................................................
   SECTION 3.19.        EMPLOYEE BENEFIT PLANS.................................................................
   SECTION 3.20.        TAXES..................................................................................
   SECTION 3.21.        PROCEEDINGS AND JUDGMENTS..............................................................
   SECTION 3.22.        INSURANCE..............................................................................
   SECTION 3.23.        EFFECT OF AGREEMENT; INAPPLICABILITY OF ANTI-TAKEOVER STATUTES.........................
   SECTION 3.24.        ASSUMED CONTRACTS......................................................................
   SECTION 3.25.        REQUIRED NON-GOVERNMENTAL CONSENTS.....................................................
   SECTION 3.26.        SOLVENCY...............................................................................
   SECTION 3.27.        FINISHED GOODS INVENTORY...............................................................
   SECTION 3.28.        VOTE REQUIRED..........................................................................
   SECTION 3.29.        NON-CONTRAVENTION; CONSENTS............................................................
   SECTION 3.30.        FAIRNESS OPINION.......................................................................
</TABLE>

                                       -i-
<PAGE>

<TABLE>
<CAPTION>
                                                                                                                Page
                                                                                                                ----
<S>                                                                                                              <C>
   SECTION 3.31.        FINANCIAL ADVISORY FEES AND AGREEMENTS.................................................
   SECTION 3.32.        ASSUMED CONTRACTS; CUSTOMER CLAIMS.....................................................
   SECTION 3.33.        SUFFICIENCY OF PURCHASED ASSETS........................................................
   SECTION 3.34.        SECTION 203 OF THE DGCL NOT APPLICABLE.................................................
   SECTION 3.35.        FULL DISCLOSURE........................................................................

ARTICLE 4 REPRESENTATIONS AND WARRANTIES OF PARENT AND ACQUISITION SUB.........................................

   SECTION 4.01.        EXISTENCE AND POWER....................................................................
   SECTION 4.02.        AUTHORIZATION..........................................................................
   SECTION 4.03.        ENFORCEABILITY.........................................................................
   SECTION 4.04.        NONCONTRAVENTION.......................................................................
   SECTION 4.05.        FINANCIAL ABILITY......................................................................
   SECTION 4.06.        NO BROKERS.............................................................................
   SECTION 4.07.        RESALE AND MANUFACTURING...............................................................

ARTICLE 5 PRE-CLOSING COVENANTS OF THE PARTIES.................................................................

   SECTION 5.01.        ACCESS AND INVESTIGATION...............................................................
   SECTION 5.02.        CONDUCT PENDING CLOSING................................................................
   SECTION 5.03.        CASUALTY PRIOR TO CLOSING..............................................................
   SECTION 5.04.        NO SOLICITATION........................................................................
   SECTION 5.05.        STOCKHOLDER APPROVAL; PROXY STATEMENT..................................................
   SECTION 5.06.        REGULATORY APPROVALS...................................................................
   SECTION 5.07.        PREPARATION AND SHIPPING OF PURCHASED ASSETS...........................................
   SECTION 5.08.        ADDITIONAL AGREEMENTS..................................................................
   SECTION 5.09.        PUBLIC ANNOUNCEMENTS...................................................................
   SECTION 5.10.        PARENT AND ACQUISITION SUB.............................................................

ARTICLE 6 CONDITIONS TO CLOSING................................................................................

   SECTION 6.01.        CONDITIONS TO PARENT'S AND ACQUISITION SUB'S OBLIGATIONS...............................
   SECTION 6.02.        CONDITIONS TO SELLER'S OBLIGATIONS.....................................................

ARTICLE 7 TERMINATION..........................................................................................

   SECTION 7.01.        TERMINATION............................................................................
   SECTION 7.02.        EFFECT OF TERMINATION..................................................................
   SECTION 7.03.        EXPENSES; TERMINATION FEES.............................................................

ARTICLE 8 POST-CLOSING COVENANTS OF THE PARTIES................................................................

   SECTION 8.01.        PUBLIC ANNOUNCEMENTS...................................................................
   SECTION 8.02.        ACCESS TO FACILITIES...................................................................
   SECTION 8.03.        SEC FILINGS............................................................................
   SECTION 8.04.        FINANCIAL STATEMENTS...................................................................
   SECTION 8.05.        FDA AND OTHER REGULATORY COMPLIANCE....................................................
   SECTION 8.06.        PRODUCT LIABILITY INSURANCE............................................................
   SECTION 8.07.        NO DISTRIBUTIONS TO STOCKHOLDERS.......................................................
   SECTION 8.08.        THIRD-PARTY CORRESPONDENCE.............................................................
   SECTION 8.09.        FURTHER ASSURANCES.....................................................................
   SECTION 8.10.        PURCHASED INTELLECTUAL PROPERTY........................................................
</TABLE>

                                      -ii-
<PAGE>

<TABLE>
<S>                                                                                                              <C>
   SECTION 8.11.        COBRA..................................................................................
   SECTION 8.12.        PRODUCT AND PRODUCT MATERIALS..........................................................
   SECTION 8.13.        NON-AFFILIATION........................................................................
   SECTION 8.14.        USE OF "CYGNUS" AND THE SWAN LOGO......................................................
   SECTION 8.15.        ALLOCATION SCHEDULE....................................................................

ARTICLE 9 INDEMNIFICATION......................................................................................

   SECTION 9.01.        BY SELLER..............................................................................
   SECTION 9.02.        BY PARENT AND ACQUISITION SUB..........................................................
   SECTION 9.03.        LIMITATIONS ON INDEMNITY...............................................................
   SECTION 9.04.        NOTICE AND DEFENSE; COSTS OF DEFENSE...................................................
   SECTION 9.05.        SURVIVAL OF REPRESENTATIONS AND WARRANTIES.............................................
   SECTION 9.06.        CHARACTERIZATION OF INDEMNITY PAYMENTS.................................................
   SECTION 9.07.        EXCLUSIVE REMEDY.......................................................................

ARTICLE 10 MISCELLANEOUS.......................................................................................

   SECTION 10.01.       ENTIRE AGREEMENT; ASSIGNMENT...........................................................
   SECTION 10.02.       NOTICES................................................................................
   SECTION 10.03.       EXPENSES...............................................................................
   SECTION 10.04.       GOVERNING LAW..........................................................................
   SECTION 10.05.       CONSENT TO JURISDICTION................................................................
   SECTION 10.06.       BANKRUPTCY QUALIFICATION...............................................................
   SECTION 10.07.       HEADINGS...............................................................................
   SECTION 10.08.       SCHEDULES..............................................................................
   SECTION 10.09.       SEVERABILITY...........................................................................
   SECTION 10.10.       RELIANCE BY PARENT AND ACQUISITION SUB.................................................
   SECTION 10.11.       COUNTERPARTS; FACSIMILE SIGNATURES; EFFECTIVENESS......................................
</TABLE>

                                      -iii-
<PAGE>

                                    EXHIBITS

<TABLE>
<S>                            <C>
Exhibit A                      Form of a Bill of Sale
Exhibit B                      Form of Assignment and Assumption Agreement
Exhibit C-1                    Form of Assignment of Trademarks
Exhibit C-2                    Form of Assignment of Patents
Exhibit C-3                    Form of Assignment of Patent Applications
Exhibit D                      Form of FDA Letter
Exhibit E                      Form of Transition Agreement
Exhibit F                      Form of Endorsement Effecting the Tail Policy
Exhibit G                      Form of BSI Letter
</TABLE>

                                    SCHEDULES

<TABLE>
<S>                          <C>
Schedule 2.01(a)             -  Equipment
Schedule 2.01(b)             -  Assumed Contracts
Schedule 2.01(c)             -  Purchased Intellectual Property
Schedule 2.01(d)             -  Inventory
Schedule 2.01(n)             -  Purchased CE Marking
Schedule 3.04(b)             -  Exceptions to Governmental or Regulatory Authority Compliance
Schedule 3.05(b)             -  FDA Filings and Approvals
Schedule 3.05(c)(iii)        -  Reports of Medical Device Reporting Regulations
Schedule 3.09(a)             -  Governmental or Regulatory Authority Certificates and Permits
Schedule 3.10                -  Liabilities
Schedule 3.12                -  Product Warranty
Schedule 3.16(e)             -  Exceptions to Right to Bring Intellectual Property Actions
Schedule 3.22                -  Insurance
Schedule 3.25                -  Required Non-Governmental Consents
Schedule 3.31(a)             -  Financial Advisory Fees
Schedule 4.02                -  Authorization
Schedule 4.04                -  Noncontravention
</TABLE>
<PAGE>

                            ASSET PURCHASE AGREEMENT

            This Asset Purchase Agreement (this "AGREEMENT") dated as of
December 16, 2004 by and among Cygnus, Inc., a Delaware corporation ("SELLER"),
Animas Corporation, a Delaware corporation ( "PARENT") and Animas Technologies
LLC, a Delaware limited liability company ("ACQUISITION SUB").

                                   BACKGROUND

            A. Seller is engaged in the business of developing and manufacturing
frequent, automatic and non-invasive glucose monitoring devices (referred to
herein as the "BUSINESS").

            B. Seller desires to sell to Acquisition Sub, and Acquisition Sub
desires to purchase from Seller, certain non-cash assets of Seller, upon the
terms and conditions hereinafter set forth.

                                    AGREEMENT

            NOW THEREFORE, in consideration of the mutual promises and covenants
set forth herein, and in reliance upon the representations and warranties
contained herein, and intending to be legally bound hereby, the parties hereto
agree as follows:

                                    ARTICLE 1
                                   DEFINITIONS

      SECTION 1.01. DEFINITIONS.

The following terms, as used herein, have the following meanings:

            "ACQUISITION PROPOSAL" shall have the meaning set forth in Section
5.04(d).

            "ACQUISITION SUB" shall have the meaning set forth in the Preamble.

            "AFFILIATE" of any Person shall mean any (a) other Person, directly
or indirectly, controlling, controlled by or under common control with such
Person or (b) director or officer of such Person. For the purposes of this
definition, "control" when used with respect to any Person, shall mean the
ownership of ten percent (10%) or more of the outstanding voting securities of
such Person or the possession, directly or indirectly, of the power to direct or
cause the direction of the management and policies of such Person, by Contract
or otherwise, and the terms "controlling" and "controlled" have meanings
correlative to the foregoing.

            "AGREEMENT" shall have the meaning set forth in the Preamble.

            "ASSUMED CONTRACTS" shall have the meaning set forth in Section
2.01(b).

            "ASSUMED LIABILITIES" shall have the meaning set forth in Section
2.03(a).

            "BOOKS AND RECORDS" shall have the meaning set forth in Section
2.01(j).

<PAGE>

            "BSI" shall have the meaning set forth in Section 3.05(e).

            "BUSINESS" shall have the meaning set forth in the Background.

            "BUSINESS EMPLOYEES" shall mean any persons currently or formerly
employed by Seller or any ERISA Affiliate (including such persons on a leave of
absence).

            "BUSINESS DAY" shall have the meaning set forth in Rule 14d-1(g)(3)
under the Exchange Act.

            "CE MARKING" shall mean the mark that is affixed to the Products
confirming they have been subject to an assessment of their conformity with the
Medical Device Directive.

            "CHOSES IN ACTION" shall have the meaning set forth in Section
2.01(h).

            "CLAIM" shall mean any demand, complaint, claim, suit, action, cause
of action, investigation, proceeding or notice by any Person, alleging actual or
potential Liability for any Loss.

            "CLOSING" shall have the meaning set forth in Section 2.05.

            "CLOSING DATE" shall have the meaning set forth in Section 2.05.

            "COBRA" shall have the meaning set forth in Section 2.03(b)(vii).

            "CODE" shall mean the Internal Revenue Code of 1986, as amended, and
the rules and regulations promulgated thereunder or in connection therewith.

            "CONFIDENTIALITY AGREEMENT" shall mean the Confidential Disclosure
Memorandum between Parent and Seller dated June 1, 2004 and the confidentiality
provisions of the Indication of Interest between Parent and Seller dated
November 15, 2004.

            "CONSENT" shall mean any Consent, approval, order or authorization
(including any Governmental Authorization) of, or any declaration, filing or
registration with, or any application, notice or report to, or any waiver by, or
any other action (whether similar or dissimilar to any of the foregoing) of, by
or with, any Person, which is necessary in order to take a specified action or
actions in a specified manner and/or to achieve a specified result.

            "CONSIDERATION" shall have the meaning set forth in Section 2.04(a).

            "CONTRACT" shall mean any written or oral contract, agreement,
instrument, order, arrangement, commitment or understanding of any nature,
including sales orders, purchase orders, leases, subleases, data processing
agreements, maintenance agreements, license agreements, sublicense agreements,
loan agreements, promissory notes, instruments, security agreements, pledge
agreements, deeds, mortgages, guaranties, indemnities, warranties, employment
agreements, consulting agreements, sales representative agreements, joint
venture agreements, buy-sell agreements, options or warrants.

                                      -2-
<PAGE>

            "COPYRIGHTS" shall mean all copyrights, copyrightable works, mask
works and databases, including, without limitation, any Software, Internet
web-sites and the content thereof, and any other works of ownership, whether
statutory or common law, registered or unregistered, and registrations for and
pending applications to register the same including all reissues, extensions and
renewals thereto, and all moral rights thereto under the Laws of any
jurisdiction.

            "COURT ORDER" shall mean any judgment, decree, edict, writ,
injunction, award, order or ruling of any Governmental or Regulatory Authority
or of any arbitration or similar panel.

            "DEFAULT" shall mean (a) any violation, breach or default, (b) the
occurrence of an event that, with the passage of time (excluding any
contractually provided for grace periods), the giving of notice or both, would
constitute a violation, breach or default, or (c) the occurrence of an event
that, with or without the passage of time, the giving of notice or both, would
give rise to a right of termination, renegotiation or acceleration.

            "DGCL" shall have the meaning set forth in Section 3.02.

            "DOCUMENTATION" shall have the meaning set forth in Section 2.01(f).

            "EFFECT" shall mean any event, occurrence, change or effect related
to the Business or Seller.

            "EMPLOYEE BENEFIT PLAN" shall mean: (a) each "employee benefit
plan," as defined in Section 3(3) of United States federal Employee Retirement
Income Security Act of 1974, as amended ("ERISA") (including any Multiemployer
Plan), and (b) all other pension, retirement, supplemental retirement,
post-retirement medical or life insurance, deferred compensation, excess
benefit, profit sharing, bonus, incentive, stock purchase, stock ownership,
stock option, stock appreciation right or other equity-based incentive,
employment, severance, salary continuation, supplemental unemployment benefits,
termination, change-of-control, health, life, disability, group insurance,
vacation, holiday and fringe benefit plan, program, Contract or arrangement,
(whether written or unwritten, qualified or nonqualified, funded or unfunded,
insured or self-insured and including any that have been frozen or terminated)
sponsored, maintained, contributed to, or required to be contributed to, by
Seller or any ERISA Affiliate for the benefit of any employees or independent
contractors or their respective dependents and beneficiaries, or under which
Seller or any ERISA Affiliate has or could have any Liability (each a "BENEFIT
PLAN" or collectively the "BENEFIT PLANS").

            "ENVIRONMENTAL LAW" shall mean any Laws or other legal requirements
relating to (i) the environment, (ii) emissions, discharges or releases of
Substances into the environment, including, without limitation, ambient air,
surface water, groundwater or land, or (iii) otherwise relating to the Handling
of Substances or wastes or the investigation, clean-up or other remediation
thereof.

            "ERISA AFFILIATE" shall mean any current or former (A) corporation
included with Seller in a controlled group of corporations within the meaning of
Section 414(b) of the Code; (B) trade or business (whether or not incorporated)
which is under common control with Seller within the meaning of Section 414(c)
of the Code; (C) member of an affiliated service group of

                                      -3-
<PAGE>

which Seller is a member within the meaning of Section 414(m) of the Code; or
(D) other Person or entity treated as an affiliate of Seller under Section
414(o) of the Code.

            "EQUIPMENT" shall have the meaning set forth in Section 2.01(a).

            "EXCHANGE ACT" shall mean the Securities Exchange Act of 1934.

            "EXCLUDED ASSETS" shall have the meaning set forth in Section 2.02.

            "EXCLUDED LIABILITIES" shall have the meaning set forth in Section
2.03(b).

            "FDA" shall mean the U.S. Food and Drug Administration.

            "FDA PERMITS" shall have the meaning set forth in Section 3.05(b).

            "FDC ACT" shall have the meaning set forth in Section 3.05(c).

            "FOREIGN DOCUMENTATION" shall have the meaning set forth in Section
2.01(g).

            "GAAP" shall mean U.S. generally accepted accounting principles
consistently applied throughout the applicable periods and includes any Law
related to accounting or the preparation of financial statements that Seller
must follow by virtue of being a public company and required to file financial
statements with the SEC from time to time.

            "GOODWILL" shall have the meaning set forth in Section 2.01(o).

            "GOVERNMENTAL AUTHORIZATION" shall mean any: (a) Permit, license,
certificate, franchise, permission, variance, clearance, approval, registration,
qualification or authorization issued, granted, given or otherwise made
available by or under the authority of any Governmental or Regulatory Authority
or pursuant to any Law; or (b) right under any Contract with any Governmental or
Regulatory Authority.

            "GOVERNMENTAL OR REGULATORY AUTHORITY" shall mean any court,
tribunal, arbitrator, authority, agency, commission, official, agency or other
instrumentality exercising governmental or regulatory authority of the United
States, any foreign country or any domestic or foreign state, province, county,
city, municipality or other political subdivision or any quasi-governmental or
regulatory body exercising authority thereunder (including the PTO).

            "HANDLING" shall mean the use, generation, emission, storage,
treatment, disposal, discharge, release or other handling or disposition of any
Substance and "HANDLED" shall mean to have done any of the foregoing.

            "INDEMNIFIED PARTY" shall mean the Seller Indemnified Party or
Parties or the Purchaser Indemnified Party or Parties, whichever the case may
be.

            "INDEMNIFYING PARTY" shall mean Seller in the case that the
Indemnified Party is the Purchaser Indemnified Party or Parties and shall mean
Parent and Acquisition Sub in the case that the Indemnified Party is the Seller
Indemnified Party or Parties.

                                      -4-
<PAGE>

            "INFRINGES" shall have the meaning set forth in Section 3.16(f).

            "INSOLVENT" shall mean with regard to a Person and on a particular
date and assuming a fair valuation of the Purchased Assets of not less than Ten
Million Dollars ($10,000,000) that: (i) such Person is not able to meet or
satisfy its obligations as they generally become due; (ii) such Person is not
paying its current obligations in the ordinary course of business as they
generally become due; or (iii) the Person's assets are less than the sum of all
of the Person's debts on such date.

            "INSURANCE POLICIES" shall have the meaning set forth in Section
3.22.

            "INSURANCE PROCEEDS" shall have the meaning set forth in Section
2.01(l).

            "INTELLECTUAL PROPERTY COMMUNICATIONS" shall have the meaning set
forth in Section 5.02(c).

            "INVENTORY" shall have the meaning set forth in Section 2.01(d).

            "ISO 13485" shall mean the international standard, adopted by the
International Standards Organization, which concerns the quality systems
applicable to manufacture of medical devices.

            "JOHNSON & JOHNSON CLAIM" shall have the meaning set forth in
Section 2.02(g).

            "LATEST BALANCE SHEET" shall have the meaning set forth in Section
3.06(b).

            "LAW" shall mean any federal, state, local, municipal, foreign or
other law, statute, charter, constitution, treaty, resolution, ordinance, code,
edict, decree, rule, regulation, guidelines, ruling or requirement issued,
enacted, adopted, promulgated, implemented or otherwise put into effect by or
under the authority of any Governmental or Regulatory Authority.

            "LIABILITY" shall mean any direct or indirect liability,
indebtedness, obligation, interest, penalty, commitment, expense, claim,
deficiency, guaranty or endorsement of or by any Person of any type, known or
unknown, asserted or unasserted and whether accrued, absolute, contingent,
matured or unmatured including but not limited to any liability for Taxes.

            "LICENSES" shall mean Contracts pursuant to which the Seller has
acquired, granted or otherwise transferred any rights in or to any of the
Trademarks, Patents, Copyrights, Software or Proprietary Rights.

            "LIEN" shall mean, with respect to any Purchased Asset, any
mortgage, lien, pledge, encumbrance, charge, or security interest of any kind in
respect of such Purchased Asset. For the purposes of this Agreement, any Person
shall be deemed to own subject to Lien any asset that it has acquired or holds
subject to the interest of a vendor or lessor under any conditional sale
agreement, capital lease or other title retention agreement relating to such
Purchased Asset.

            "LOSS" shall mean any and all damages (including direct, incidental,
consequential and special damages), losses, obligations, deficiencies,
Liabilities, Liens, penalties, fines, interest,

                                      -5-
<PAGE>

costs and expenses (including, without limitation, court costs, fees punitive
damages and disbursements of attorneys, accountants, consultants and other
experts, or other expenses of investigating, prosecuting or defending any
Proceeding, Claim or Default).

            "MATERIAL ADVERSE EFFECT" shall mean any Effect (considered alone or
together with any other matter or matters) that is, or would reasonably be
expected to be, materially adverse to (i) the financial condition of Seller,
(ii) the Purchased Assets, (iii) the amount of Assumed Liabilities, (iv) the
ability of Seller to satisfy in full the Excluded Liabilities after the Closing
Date, or (v) the ability of Seller to consummate the transactions contemplated
by the Agreement or to perform any of its obligations under the Agreement;
provided, however, that in no event shall any of the following be deemed to
constitute, nor shall any of the following be taken into account in determining
whether there has been a Material Adverse Effect: (a) any Effect resulting from
compliance with the terms and conditions of this Agreement, (b) any Effect that
results from changes in general economic, business or capital markets
conditions, (c) any Effect that results from changes in Laws after the date
hereof, and (d) any Effect resulting from an outbreak or escalation of
hostilities, the declaration national emergency or war, or the occurrence of any
acts of terrorism in the United States; provided further that the fact that
Seller has and will continue to curtail its operations and plans to dissolve its
corporate existence and distribute its assets does not constitute a Material
Adverse Effect.

            "MEDICAL DEVICE DIRECTIVE" shall mean the European Council Directive
93/42/EEC of 14 June 1993 concerning medical devices.

            "MULTIEMPLOYER PLAN" has the meaning set forth in Section 3(37) of
ERISA.

            "NON-REFUNDABLE PREPAYMENTS" shall have the meaning set forth in
Section 2.01(e).

            "PARENT" shall have the meaning set forth in the Preamble.

            "PATENT AND TRADEMARK LISTING" shall have the meaning set forth in
Section 5.02(d).

            "PATENTS" shall mean patents and patent applications (including,
without limitation, provisional applications, utility applications and design
applications), including, without limitation, reissues, patents of addition,
continuations, continuations-in-part, substitutions, additions, divisionals,
renewals, registrations, confirmations, re-examinations, certificates of
inventorship, extensions and the like, any foreign or international equivalent
of any of the foregoing, and any domestic or foreign patents or patent
applications claiming priority to any of the above.

            "PAY-OFF LETTER" shall have the meaning set forth in Section 6.01(i)

            "PERMITS" shall have the meaning set forth in Section 3.09(a).

            "PERMITTED LIENS" shall have the meaning set forth in Section
3.08(a).

                                      -6-
<PAGE>
            "PERSON" shall mean an individual or a corporation, partnership,
limited liability company, association, trust, or any other entity or
organization, including a Governmental or Regulatory Authority.

            "PMA" shall mean a premarket approval application filed with the
FDA.

            "PRE-CLOSING PERIOD" shall have the meaning set forth in Section
5.01(a).

            "PROCEEDING" shall mean any Claim, suit, action, litigation,
investigation, arbitration, administrative hearing, audit or other proceeding of
any nature (including any civil, criminal, administrative, investigative, or
appellate proceeding).

            "PRODUCTS" shall mean the GlucoWatch Biographer line of products,
including the AutoSensor and Analyzer.

            "PROPRIETARY RIGHTS" shall mean categories of trade secrets, trade
dress, know-how, inventions, invention disclosures (whether or not patentable
and whether or not reduced to practice), inventor rights, reports, discoveries,
developments, research and test data, blueprints, technology, ideas,
compositions, quality records, engineering notebooks, models, processes,
procedures, prototypes, patent records, manufacturing and product procedures and
techniques, troubleshooting procedures, failure/defect analysis data, drawings,
specifications, designs, algorithms, ingredient or component lists, formulae,
plans, proposals, technical data, copyrightable works, mask works, databases,
financial, marketing, customer and business data, pricing and cost information,
business and marketing plans, selling information, marketing information,
customer and supplier lists and information, and all other confidential and
proprietary information and industrial property rights.

            "PROXY STATEMENT" shall mean the proxy statement of Seller to be
sent to Seller's stockholders in connection with Seller Stockholders' Meeting.

            "PTO" shall mean the United States Patent and Trademark Office and
any foreign governmental office equivalent.

            "PURCHASED ASSETS" shall have the meaning set forth in Section
2.01(o).

            "PURCHASED CE MARKING" shall have the meaning set forth in Section
2.01(n).

            "PURCHASED PMA" shall have the meaning set forth in Section 2.01(m).

            "PURCHASED INTELLECTUAL PROPERTY" shall have the meaning set forth
in Section 2.01(c).

            "PURCHASER COLLATERAL DOCUMENTS" shall have the meaning set forth in
Section 4.02.

            "PURCHASER INDEMNIFIED PARTIES" shall have the meaning set forth in
Section 9.01.

                                      -7-
<PAGE>

            "PURCHASER INDEMNIFIED PARTY" shall have the meaning set forth in
Section 9.01.

            "QSR" shall have the meaning set forth in Section 3.05(c)(ii).

            "REAL PROPERTY" shall mean any real estate, land, building,
condominium, town house, structure or other real property of any nature, all
shares of stock or other ownership interests in cooperative or condominium
associations or other forms of ownership interest through which interests in
real estate may be held, and all appurtenant and ancillary rights thereto,
including easements, covenants, water rights, sewer rights and utility rights.

            "REDWOOD CITY FACILITY" shall mean the facilities leased by Seller
pursuant to the Redwood City Lease.

            "REDWOOD CITY LEASE" shall mean the Ten-Year Industrial Net Lease
Agreement (Building No. 2) by and between Seller and Seaport Centre Venture
Phase I dated September 27, 1988, and all amendments thereto.

            "REPORTABLE CONTINGENT LIABILITIES" shall mean (i) any Liability
which appears on the Latest Balance Sheet, (ii) any Liability that Seller has
established, or would be required by GAAP to establish, a reserve for, and (iii)
any Liability that Seller has disclosed or discussed, or would be required by
GAAP to disclose or discuss, in its financial statements or the notes thereto.

            "REPRESENTATIVES" shall have the meaning set forth in Section
5.04(a).

            "REQUIRED NON-GOVERNMENTAL CONSENTS" shall have the meaning set
forth in Section 3.25.

            "REQUIRED SELLER STOCKHOLDER VOTE" shall have the meaning set forth
in Section 3.28.

            "SANOFI" shall mean Sanofi Aventis (f/k/a Sanofi, S.A., also f/k/a
Sanofi-Synethelabo).

            "SANOFI LIENS" shall mean all Liens on the Purchased Assets in favor
of Sanofi related to any obligations of Seller to Sanofi arising out of the
Final Award and amendments thereto issued by the International Court of
Arbitration on December 11, 1997 and subsequently entered as judgments of the
United States District Court of California.

            "SEC" shall have the meaning set forth in Section 3.06(a).

            "SECURITIES ACT" shall mean the Securities Act of 1933.

            "SELLER" shall have the meaning set forth in the Preamble.

            "SELLER BOARD RECOMMENDATION" shall have the meaning set forth in
Section 3.02.

                                      -8-
<PAGE>

            "SELLER COLLATERAL DOCUMENTS" shall have the meaning set forth in
Section 3.23(a).

            "SELLER COMMON STOCK" shall have the meaning set forth in Section
3.03.

            "SELLER INDEMNIFIED PARTIES" shall have the meaning set forth in
Section 9.02.

            "SELLER INDEMNIFIED PARTY" shall have the meaning set forth in
Section 9.02.

            "SELLER SEC DOCUMENTS" shall have the meaning set forth in Section
3.06(a).

            "SELLER STOCKHOLDERS' MEETING" shall have the meaning set forth in
Section 5.05(b).

            "SOFTWARE" shall mean all software programs, including all versions
of source code, object code, assembly language, compiler language, machine code,
and all other computer instructions, code, and languages embodied in computer
software of any nature whatsoever and whether for use in or in conjunction with
a mainframe computer, personal computer (desk top, lap top or hand held),
personal digital assistant or any other programmable hardware or device,
computer systems, computer hardware, network infrastructure and related
equipment, and all error corrections, updates, upgrades, enhancements,
translations, modifications, adaptations, further developments, derivative works
thereto, and other changes or functionality additions of any kind; and all
designs and design documents (whether detailed or not), technical summaries, and
documentation (including flow charts, logic diagrams, white papers, manuals,
guides and specifications), firmware and middleware associated with the
foregoing.

            "SOLVENT" shall mean with regard to a Person and on a particular
date and assuming a fair valuation of the Purchased Assets of not less than Ten
Million Dollars ($10,000,000) that: (i) such Person is able to meet or satisfy
its obligations as they generally become due; (ii) such Person is paying its
current obligations in the ordinary course of business as they generally become
due; and (iii) the Person's assets are equal to or greater than the sum of all
of the Person's debts on such date.

            "SOX" shall mean the Sarbanes-Oxley Act of 2002.

            "SPECIFIED CONTRACTS" shall have the meaning set forth in Section
3.17(a).

            "SUBSIDIARY" shall mean the following: an entity shall be deemed to
be a "Subsidiary" of another Person if such Person directly or indirectly owns
or purports to own, beneficially or of record, (a) an amount of voting
securities of other interests in such entity that is sufficient to enable such
Person to elect at least a majority of the members of such entity's board of
directors or other governing body, or (b) at least 50% of the outstanding equity
or financial interests of such entity.

            "SUBSTANCE" shall mean any "hazardous substance," "hazardous waste,"
"pollutant," or "toxic substance" (as defined or regulated by any Environmental
Law), petroleum or

                                      -9-
<PAGE>

petroleum product or byproduct, polychlorinated biphenyl or asbestos as to which
Liability or standards of conduct are imposed under Environmental Laws.

            "SUPERIOR PROPOSAL" shall have the meaning set forth in Section
5.04(d).

            "TAKEOVER LAWS" shall have the meaning set forth in Section 3.23(c).

            "TAIL POLICY" shall have the meaning set forth in Section 6.01(h).

            "TAX" or "TAXES" shall mean (i) any United States federal, state or
local or any foreign taxes, levies, duties, fees, assessments, deductions,
withholdings, or other charges of whatever nature, including income, gross
receipts, net proceeds, license, payroll, employment, excise, severance, stamp,
occupation, premium, windfall profits, environmental (including taxes under
Section 59A of the Code), customs, capital stock, franchise, profits, employee
income, withholding, social security (or similar), unemployment, disability,
real property, personal property, sales, use, transfer, registration, value
added, alternative or add-on minimum, estimated or other taxes, assessments,
duties, fees, levies or other governmental charges of any kind whatever, now or
hereafter levied by the United States of America or any Governmental or
Regulatory Authority, whether disputed or not, including any interest, penalty
or addition thereto, and including all deposits required in connection
therewith; (ii) any Liability for or in respect of the payment of any amount of
a type described in clause (i) of this definition as a result of being a member
of an affiliated, combined, consolidated, unitary or other group for tax
purposes; and (iii) any Liability for or in respect of the payment of any amount
described in clauses (i) or (ii) of this definition as a transferee or
successor, by Contract or otherwise.

            "TAX LIENS" shall have the meaning set forth in Section 3.08(a).

            "TAX RETURNS" shall mean all returns, declarations, reports, claims
for refund, information returns or statements relating to Taxes, including any
schedules or attachments thereto, and including any amendments thereof,
including without limitation estimated tax returns, information returns or
reports with respect to backup withholding and other payments to third parties.

            "TERMINATION DATE" shall mean May 31, 2005.

            "TERMINATION FEE" shall have the meaning set forth in Section
7.03(c).

            "TRADEMARKS" shall mean trademarks, service marks, trade names,
corporate names, company names, business names, fictitious business names, trade
styles, uniform resource locators (URLs), domain names, trade dress, any other
names and locators associated with the Internet, other source of business
identifiers, whether registered or unregistered and whether or not currently in
use, and registrations, applications to register and all of the goodwill of the
business related to the foregoing.

            "TRANSFERRED PERMITS" shall have the meaning set forth in Section
2.01(k).

            "TRIGGERING EVENT" shall mean the occurrence of the following: (i)
the board of directors of Seller shall have failed to recommend that Seller's
stockholders approve and adopt

                                      -10-
<PAGE>

the Agreement, or shall have withdrawn or modified in a manner adverse to either
Acquisition Sub or Parent the Seller Board Recommendation; (ii) Seller shall
have failed to include in the Proxy Statement the Seller Board Recommendation or
a statement to the effect that the board of directors of Seller has determined
and believes that the transactions contemplated by this Agreement are in the
best interests of Seller's stockholders; (iii) the board of directors of Seller
shall have approved, endorsed or recommended any Acquisition Proposal; (iv)
Seller shall have entered into any letter of intent or similar document or any
Contract relating to any Acquisition Proposal (other than a confidentiality
agreement that is entered into in accordance with Section 5.04(a)); (v) a tender
or exchange offer relating to securities of Seller shall have been commenced and
Seller shall not have sent to its security holders, within ten (10) Business
Days after the commencement of such tender or exchange offer, a statement
disclosing that Seller recommends rejection of such tender or exchange offer; or
(vi) Seller or any Representative of Seller shall have materially breached any
of the provisions set forth in Section 5.04.

            "UCAL AGREEMENT" shall have the meaning set forth in Section
2.03(b)(viii).

            "WARN ACT" shall have the meaning set forth in Section 3.18(d).

            "WARRANTIES" shall have the meaning set forth in Section 2.01(i).

      SECTION 1.02. INTERPRETATION AND RULES OF CONSTRUCTION.

Definitions contained in this Agreement apply to singular as well as the plural
forms of such terms and to the masculine as well as to the feminine and neuter
genders of such terms. Words in the singular shall be held to include the plural
and vice versa, and words of one gender shall be held to include the other
gender as the context requires. The terms "hereof," "herein," "hereby" and
"herewith" and words of similar import shall, unless otherwise stated, be
construed to refer to this Agreement as a whole and not to any particular
provision of this Agreement. The terms "includes" and the word "including" and
words of similar import shall be deemed to be followed by the words "without
limitation." Article, Section, paragraph, Exhibit and Schedule references are to
the Articles, Sections, paragraphs, Exhibits and Schedules to this Agreement
unless otherwise specified.

                                   ARTICLE 2
                           PURCHASE AND SALE OF ASSETS

      SECTION 2.01. PURCHASE AND SALE OF ASSETS.

In accordance with and subject to the terms and conditions of this Agreement, on
the Closing Date, Seller shall sell and assign to Acquisition Sub, and
Acquisition Sub shall purchase from Seller, free and clear of all Liens all
right, title and interest in and to the following assets, properties, rights and
claims of Seller:

            (a) all of Seller's machinery, equipment, supplies, tools and other
fixed assets (including, but not limited to product development equipment and
production equipment), including those items listed on Schedule 2.01(a) attached
hereto (collectively, the "EQUIPMENT");

                                      -11-
<PAGE>

            (b) the Contracts listed on Schedule 2.01(b) attached hereto, which
include, but are not limited to, all distributor, manufacturing and license
agreements related to the Products (collectively, the "ASSUMED CONTRACTS");

            (c) all of Seller's Intellectual Property, including without
limitation Patents, Trademarks, Copyrights, Software, and Proprietary Rights,
and any licenses thereto, including those Patents and Trademarks listed on
Schedule 2.01(c) attached hereto (collectively, the "PURCHASED INTELLECTUAL
PROPERTY");

            (d) all finished goods, inventories and all raw materials,
work-in-process inventories, packaging materials and other items of tangible
property, including products or supplies on hand or in transit, whether located
in public or off-site warehouses or on property leased by Seller, including
those listed on Schedule 2.01(d) attached hereto (collectively, the
"INVENTORY");

            (e) all rights to any non-refundable prepayments under any of the
Assumed Contracts (the "NON-REFUNDABLE PREPAYMENTS");

            (f) all documents, records, and files (both written and electronic)
concerning the Products relating to or arising from activities such as
development, design, testing, clinical study, labeling, manufacture, and
distribution of the Products and any modifications thereto and from FDA
regulatory compliance activities, including but not limited to: the entire PMA;
all PMA supplements; all correspondence with the FDA related to the Products;
all Device Master Records (as such term is defined in the QSR), Design History
Files (as such term is defined in the QSR) and Device History Records (as such
term is defined in the QSR); all manufacturing and quality control records,
documents, files, and standard operating procedures necessary to enable Parent
or Acquisition Sub to manufacture (or have a third party manufacture) the
Products in substantial compliance with the QSR; and all documents, records, and
files of any kind established, kept or maintained in support of PMA approval for
the Products and/or pursuant to any and all FDA regulatory requirements
(collectively the "DOCUMENTATION");

            (g) all documents, records, and files (both written and electronic)
concerning the Products relating to or arising from activities such as
development, design, testing, clinical study, labeling, manufacture, and
distribution of the Products and any modifications thereto and arising from any
foreign regulatory compliance requirements, including but not limited to: all
obligations and rights governed by the Medical Device Directive; all
correspondence with any foreign regulatory body or authority related to the
Products; all manufacturing and quality control records, documents, files, and
standard operating procedures necessary to enable Parent or Acquisition Sub to
manufacture (or have a third party manufacture) the Products in substantial
compliance with any foreign regulatory compliance requirements; and all
documents, records, and files of any kind established, kept or maintained in
support of any foreign regulatory approval for the Products and/or pursuant to
any and all foreign regulatory requirements (collectively the "FOREIGN
DOCUMENTATION");

            (h) all Claims, or rights of Seller which would give rise to a
Claim, by Seller as of the Closing Date, except for any Claims related to the
Excluded Assets and Excluded Liabilities

                                      -12-
<PAGE>

referenced in Section 2.02 and Section 2.03, respectively, below (collectively
the "CHOSES IN ACTION");

            (i) all guarantees, warranties, indemnities and similar rights in
favor of Seller with respect to any of the Purchased Assets (collectively the
"WARRANTIES");

            (j) all of Seller's books and records related to the Purchased
Assets, subject to the right of Seller to retain copies of all or any portion of
such books and records (collectively the "BOOKS AND RECORDS"), except for any
books and records included as part of the Excluded Assets referenced in Section
2.02 below;

            (k) to the extent transferable or assignable, all of the Permits of
Seller related to the Purchased Assets (the "TRANSFERRED PERMITS");

            (l) any insurance proceeds or rights to insurance proceeds that have
become Purchased Assets pursuant to Section 5.03 hereof ("INSURANCE PROCEEDS");

            (m) all of Seller's rights in the PMA P990026 and supplements as set
forth on Schedule 3.05(b) and as approved by the FDA (the "PURCHASED PMA");

            (n) all of Seller's rights in the CE Marking as set forth on
Schedule 2.01(n) and as approved by the United Kingdom BSI (the "PURCHASED CE
MARKING"); and

            (o) all goodwill of Seller (the "GOODWILL" collectively with the
Purchased CE Marking, Purchased PMA, Insurance Proceeds, Transferred Permits,
Books and Records, Warranties, Choses in Action, Foreign Documentation,
Documentation, Inventory, Non-Refundable Prepayments, Purchased Intellectual
Property, Assumed Contracts and Equipment, the "PURCHASED ASSETS").

      SECTION 2.02. EXCLUDED ASSETS.

Notwithstanding anything to the contrary in this Agreement, Acquisition Sub and
Parent expressly understand and agree that the following assets and properties
of Seller (collectively the "EXCLUDED ASSETS") shall be excluded from the
Purchased Assets:

            (a) all cash, cash equivalents and investments of Seller;

            (b) all accounts and notes receivable of Seller, and any refunds due
to Seller including but not limited to refunds on prepaid expenses and
insurance;

            (c) all of Seller's potential Tax refunds or adjustments;

            (d) the Redwood City Lease;

            (e) except as listed on Schedule 2.01(a), all office and laboratory
equipment, furniture, supplies and computers that are not directly utilized with
the Purchased Assets and that are located at the Redwood City Facility;

                                      -13-
<PAGE>

            (f) any Contracts with any Business Employee, including without
limitation, any termination, employment, retention, change-in-control or
severance Contract;

            (g) all rights and Claims in favor of Seller, books, records and
other documentation with respect to Seller's arbitration and contractual dispute
with Ortho-McNeil Pharmaceutical, Inc./Johnson & Johnson concerning the purchase
of assets set forth in the November 17, 1999 Asset Purchase Agreement between
Seller and Ortho-McNeil Pharmaceutical, Inc. and related documents (the "JOHNSON
& JOHNSON CLAIM");

            (h) all rights with respect to Seller's arbitration with Sanofi;

            (i) all financial records of Seller;

            (j) all employee and personnel records of Seller;

            (k) all Contracts of Seller other than the Assumed Contracts;

            (l) the minute books and stock transfer records of Seller, and any
other documents and legal files relating to the organization, maintenance and
existence of Seller as a corporation; and

            (m) any insurance proceeds that have become Excluded Assets pursuant
to Section 5.03.

      SECTION 2.03. LIABILITIES.

            (a) Except as limited by Section 2.03(b), at Closing, Acquisition
Sub shall assume and become responsible for (i) Liabilities under the Assumed
Contracts arising on or after the Closing Date; (ii) any Liabilities that have
become Assumed Liabilities pursuant to Section 5.03; and (iii) any tort
Liability (including without limitation, any contingent tort Liability) related
to or arising out of any of the Products sold on or after the Closing Date
(collectively, the "ASSUMED LIABILITIES").

(b) Notwithstanding anything to the contrary in this Agreement, except for the
Assumed Liabilities, neither Parent nor Acquisition Sub shall assume, nor shall
either of them be deemed to assume, any Liability of Seller of any kind or
nature (collectively, the "EXCLUDED LIABILITIES"). In furtherance and not in
limitation of the foregoing, neither Parent nor Acquisition Sub is or shall
become (i) by reason of the purchase of the Purchased Assets, (ii) by reason of
any other act or failure to act on either of their part, or (iii) for any other
reason, liable in any manner for any Liabilities of Seller. Without limiting the
generality of the foregoing, and without regard to whether any Law, Governmental
or Regulatory Authority, or other third party may impose any Liability of
Seller, in whole or in part, on Acquisition Sub or Parent, neither Parent nor
Acquisition Sub shall assume, and Seller shall continue to be liable for, all
Liabilities of Seller (including, without limitation, any tort Liability of
Seller resulting from the sale of the Products prior to the Closing Date and
warranties in connection with any goods or services provided or sold by Seller
on or prior to the Closing Date, provided that Acquisition Sub or Parent will
supply replacement product on such warranty claims to the extent Acquisition Sub
or Parent has such replacement product in its finished goods inventory at the
time of such warranty

                                      -14-
<PAGE>

claim and such replacement product is not beyond its expiration date) not
otherwise specifically assumed by either Parent or Acquisition Sub under this
Agreement, including, without limitation, any Liability of Seller:

                  (i) for Taxes;

                  (ii) for accounts or trade payables;

                  (iii) related to Environmental Laws;

                  (iv) related to the Redwood City Lease;

                  (v) with respect to the Johnson & Johnson Claim;

                  (vi) with respect to Seller's arbitration with Sanofi;

                  (vii) with respect to any termination, employment or severance
agreement or obligation with any current or former Business Employee which exist
as of the date hereof or which shall arise in the future including, but not
limited to, (A) any notification, debt, obligation, contribution or other
Liability under the WARN Act, any successor United States federal Law, and any
other applicable plant closing notification Law, with respect to any mass
layoff, layoff or plant closing relating to the Business and (B) any and all
obligations arising under the continuation coverage requirements of Section
4980B of the Code and the Consolidated Omnibus Budget Reconciliation Act of 1985
(29 U.S.C. Sections 1161-1169) ("COBRA") or other applicable Law with respect to
the Business Employees and their beneficiaries who experience a "Qualifying
Event" (as defined in COBRA) on or after the Closing Date;

                  (viii) the minimum royalties due under Seller's license
agreement with the University of California (the "UCAL AGREEMENT") for the year
2004 (payable in February 2005);

                  (ix) with respect to any of the items listed on Schedule
3.04(b);

                  (x) with respect to any tort Liability (including without
limitation, any contingent tort Liability) related to or arising out of any of
the Products sold prior to the Closing Date; and

                  (xi) related to any termination or settlement Liabilities with
Seller's suppliers or distributors.

      SECTION 2.04. CONSIDERATION; CASH PAYMENTS AT CLOSING.

            (a) The aggregate purchase price for the Purchased Assets shall be
Ten Million Dollars ($10,000,000) (the "CONSIDERATION").

            (b) At the Closing, Acquisition Sub shall pay the Consideration as
follows:

                                      -15-
<PAGE>

                  (i) the amount set forth in the Pay-Off Letter shall be paid
to Sanofi thereof by wire transfer of immediately available funds to the
accounts designated in the Pay-Off Letter;

                  (ii) an amount, if any, equal to the Consideration less any
amount paid by Acquisition Sub in clause (i), shall be paid to Seller by wire
transfer of immediately available funds to the account designated by Seller.
Seller shall provide written notice to Acquisition Sub of the account to receive
such wire transfer at least three (3) Business Days prior to the Closing Date.

      SECTION 2.05. THE CLOSING.

The purchase and sale of the Purchased Assets shall take place (the "CLOSING")
at the offices of Pepper Hamilton LLP, 3000 Two Logan Square, Philadelphia, PA
19103, commencing at 1:00 p.m. local time on the third (3rd) Business Day
following the date upon which all conditions to the obligations of the parties
to consummate the transactions contemplated hereby (other than conditions with
respect to actions the respective parties will take at the Closing itself) have
been satisfied or waived or such other date or time as the parties may mutually
determine but in no case later than the Termination Date. The date and time of
the Closing are referred to herein as the "CLOSING DATE."

      SECTION 2.06. GUARANTY OF PARENT.

Parent hereby absolutely and unconditionally guarantees all obligations of the
Acquisition Sub under this Agreement, including without limitation the payment
of the Consideration set forth in Section 2.04. Parent acknowledges and agrees
that: (i) this is a guarantee of payment and performance and not of
collectibility only; (ii) Parent's responsibility for its obligations under this
Agreement are in no way conditioned upon any requirement that Seller and the
Seller Indemnified Parties first attempt to collect from Acquisition Sub with
respect to any of Parent's and Acquisition Sub's obligations hereunder; and
(iii) Parent hereby waives any and all suretyship protections that are waivable
under applicable Law.

                                    ARTICLE 3
                    REPRESENTATIONS AND WARRANTIES OF SELLER

Seller represents and warrants to Parent and Acquisition Sub as follows:

      SECTION 3.01. ORGANIZATION.

Seller is a corporation duly organized, validly existing and in good standing
under the Laws of the State of Delaware. Seller possesses the full corporate
power and authority to own its assets, including without limitation the
Purchased Assets. Seller is duly qualified or registered to do business in each
jurisdiction where such qualification or registration is required by applicable
Law, except where the failure to be duly qualified or registered would not have
a Material Adverse Effect.

      SECTION 3.02. SELLER ACTION.

                                      -16-
<PAGE>

Seller's board of directors, at a meeting duly called and held, has by the
unanimous vote of all directors of Seller (i) determined that this Agreement and
the transactions contemplated hereby, are fair to Seller and in the best
interests of Seller and its stockholders, (ii) approved and adopted this
Agreement and the transactions contemplated hereby, in accordance with the
requirements of the Delaware General Corporation Law Act ("DGCL"), (iii)
declared that this Agreement is advisable, and (iv) resolved to recommend that
stockholders of Seller approve and adopt this Agreement (all of the foregoing
clauses (i) through (iv) shall collectively constitute the "SELLER BOARD
RECOMMENDATION").

      SECTION 3.03. CAPITAL STOCK.

As of December 1, 2004, the authorized capital stock of Seller consisted of (i)
ninety-five million (95,000,000) shares of common stock, par value $.001 per
share ("SELLER COMMON STOCK"), of which forty-one million nine thousand and two
hundred fifty one (41,009,251) shares were issued and outstanding as of that
date; and (ii) five million (5,000,000) shares of preferred stock, par value
$.001 per share of which zero (0) shares were issued and outstanding or held by
Seller in its treasury as of such date. As of the date hereof, there are fewer
than two thousand (2,000) holders of record of Seller Common Stock.

      SECTION 3.04. COMPLIANCE WITH LAW.

Unless addressed elsewhere in this Article 3 with respect to the compliance with
specific Laws or categories of Laws:

            (a) The operations of Seller, the conduct of the Business, as and
where the Business has been or presently is conducted, and the ownership,
possession and use of the Purchased Assets of Seller has complied and currently
do comply with all applicable Laws, including without limitation, SOX, except
where the failure to have complied or to be in compliance would not result in a
Material Adverse Effect.

            (b) Except as described on Schedule 3.04(b), from January 1, 2004
through the date of this Agreement, Seller has not received any notice, charge,
claim, complaint, citation, action or assertion from any Governmental or
Regulatory Authority regarding any actual or possible material violation of, or
failure to comply in any material respect with, any Law.

      SECTION 3.05. FDA AND OTHER REGULATORY COMPLIANCE.

            (a) Seller only sells its Products in the United States and the
United Kingdom.

            (b)Seller has made available to Parent all registrations,
applications, licenses, requests for exemption, permits, listings or other
Governmental Authorizations filed by Seller with the FDA (a listing of which is
attached hereto as Schedule 3.05(b)) (the "FDA PERMITS"). Other than as listed
on Schedule 3.05(b) and Schedule 3.09(a), Seller is not required to file, obtain
or maintain any registration, application, license, request for exemption,
permit, listing or other Governmental Authorization with the FDA or any other
Governmental or Regulatory Authority required to conduct the Business. Seller
has operated in compliance, in all material respects, with the FDA Permits. All
FDA Permits are valid and in full force and effect.

                                      -17-
<PAGE>

            (c)None of Seller's Products are misbranded, adulterated, or
otherwise in violation of the Federal Food, Drug, and Cosmetic Act ("FDC ACT")
and the regulations thereunder. Seller has complied with the provisions of the
FDC Act and regulations thereunder applicable to the conduct of the Business.
Such compliance includes, but is not limited to, the following:

                  (i)The Products have been commercially distributed in
compliance with the Conditions of Approval set forth by the FDA in Seller's PMA
approval letter ("CONDITIONS OF APPROVAL") included in the Purchased PMA. Seller
has complied in all material respects with all Conditions of Approval of the
Purchased PMA.

                  (ii) The Products, including those in Inventory, have been
manufactured in accordance with applicable requirements of the Quality System
Regulation, 21 C.F.R. Part 820 ("QSR").

                  (iii) Seller has established, kept, and maintained all
records, documentation and files required by: the Medical Device Reporting
regulation (21 C.F.R. Part 803); the Medical Device, Reports of Corrections and
Removals regulation (21 C.F.R. Part 806), and the QSR. Seller has submitted to
the FDA all reports required under the foregoing regulations (21 C.F.R. Parts
803, 806, and 820). A full and complete listing of MDR reports filed with the
FDA under 21 C.F.R. Part 803 is attached hereto as Schedule 3.05(c)(iii).

                  (iv) All complaints about the Products have been timely
reviewed, evaluated, and investigated as appropriate, and adequate corrective
and preventive action has been or is in the process of being timely implemented,
all as required under 21 C.F.R. Sections 820.100, 820.198 and other applicable
provisions of the QSR. Seller has provided Parent with a list of all such
complaints.

                  (v)Seller has labeled, advertised, and promoted its Products
in accordance with the provisions of the FDC Act, the FDA's implementing
regulations, and the Conditions of Approval of the Purchased PMA.

                  (vi) FDA has categorized the Products as "waived" under the
Clinical Laboratory Improvement Amendments of 1988.

            (d)There are no Form 483 inspection reports, untitled or warning
letters, investigations, actions, suits, or Proceedings pending or, to the
knowledge of Seller, threatened by the FDA, the Department of Justice, or the
Department of Health and Human Services against Seller, or any officer or
employee, seeking or that could potentially result in: revised labeling or
advertising; voluntary or mandatory recalls; repair, replacement or refunds;
injunction; product seizure; limitations, suspension or revocation of any
clearance, license, approval or authorization of Seller; or the imposition of
civil or criminal fines or penalties. There are no rulemaking or similar
Proceedings before the FDA or comparable Governmental or Regulatory Authority
that involve or affect Seller.

            (e)Seller has submitted all reports and other documentation
necessary to be submitted in accordance with all applicable Laws of the United
Kingdom. Seller has correctly affixed the CE Marking to the Products after a
conformity assessment by the British Standards

                                      -18-
<PAGE>

Institute ("BSI"). Seller has labeled, advertised, and promoted its devices in
conformity with all applicable foreign Laws. Neither Seller nor its distribution
partners, if any, have received notification of the violation of any applicable
regulatory Law administered or issued by any Governmental or Regulatory
Authority of the United Kingdom, European Union or any other foreign
jurisdiction. Seller is in compliance with all applicable foreign regulatory
Law.

      SECTION 3.06. SEC FILINGS.

            (a) Seller has made available to Parent accurate and complete copies
of all registration statements, definitive proxy statements and other
statements, reports, schedules, forms and other documents (and all amendments or
supplements thereto) filed or furnished by Seller with the Securities and
Exchange Commission (the "SEC") since January 1, 2004 (the "SELLER SEC
DOCUMENTS"). All statements, reports, schedules, forms and other documents
required to have been filed or furnished by Seller with the SEC since January 1,
2004 have been so filed or furnished and in a timely manner. Each of the Seller
SEC Documents complies in all material respects with the applicable requirements
of SOX, the Securities Act or the Exchange Act (as the case may be); and none of
the Seller SEC Documents when filed contained any untrue statement of a material
fact or omitted to state a material fact required to be stated therein or
necessary in order to make the statements therein, in the light of the
circumstances under which they were made, not misleading.

            (b) The consolidated financial statements (including any related
notes) contained in Seller SEC Documents: (i) when filed, complied as to form in
all material respects with the published rules and regulations of the SEC
applicable thereto; (ii) when filed, were prepared in accordance with GAAP
(except as may be indicated in the notes to such financial statements or, in the
case of unaudited interim statements, as permitted by Form 10-Q of the SEC, and
except that the unaudited interim financial statements may not contain footnotes
and are subject to normal and recurring year-end adjustments), and (iii) when
filed, fairly presented in all material respects the consolidated financial
position of Seller as of the respective dates thereof and the consolidated
results of operations and cash flows of Seller for the periods covered thereby,
except that the unaudited interim financial statements were or are subject to
normal and recurring year-end adjustments. The unaudited balance sheet of Seller
as of September 30, 2004 included in Seller's Quarterly Report on Form 10-Q for
the quarter ended September 30, 2004 is sometimes referred to as the "LATEST
BALANCE SHEET".

      SECTION 3.07. IMPORT/EXPORT LAWS.

Seller is currently in compliance with all Laws related to the import and export
of items into and out of the United States and the terms and conditions of any
Permits relating to the export or import of any items (whether tangible
property, Intellectual Property or otherwise) except where the failure to be in
compliance would not result in a Material Adverse Effect. Since December 16,
1999, Seller has not received any Claims of past or present unlawful export or
import of any items or has received any information that forms or could form the
basis of any such Claim against Seller whose Liability for such a Claim Seller
has or may have retained or assumed whether by Contract or operation of law.

                                      -19-
<PAGE>

      SECTION 3.08. ASSETS.

            (a) Seller has good and transferable title to all of the Purchased
Assets and has the right to transfer all rights, title and interest in the
Purchased Assets, free and clear of any Lien other than (i) Liens securing
Taxes, all of which are due but not delinquent or are being contested in good
faith ("TAX LIENS") and (ii) the Sanofi Liens ((i) and (ii) collectively are the
"PERMITTED LIENS").

            (b) All Equipment is in commercially reasonable operating condition
and repair, subject to normal wear and is useable in the ordinary course of
Business.

      SECTION 3.09. PERMITS.

            (a) Seller holds all clearances, approvals, registrations,
authorizations, and orders of any Governmental or Regulatory Authority required
for the conduct of the Business and the Purchased Assets (the "PERMITS") (a
listing of which is attached hereto as Schedule 3.09(a) and Schedule 2.01(n)).
Seller is operating in compliance, in all material respects, with all of the
Permits. All of the Permits are valid and in full force and effect.

            (b) Neither the execution and delivery of this Agreement, nor the
consummation of the transactions contemplated hereby, will result in the
termination or adverse modification of any of the Permits held by Seller, and
all of the Permits used in the operation of the Purchased Assets will, to the
extent permitted by Law or Governmental or Regulatory Authority, be transferred
to Acquisition Sub or Parent at Closing.

      SECTION 3.10. LIABILITIES.

Seller does not have any material liabilities other than (i) liabilities
reflected on the Latest Balance Sheet or in the notes thereto, (ii) liabilities
set forth on Schedule 3.10, (iii) liabilities under any Contracts, provided that
as of September 30, 2004, no such liability consisted of or resulted from a
Default under any such Contract, and (iv) liabilities incurred since September
30, 2004 and not in breach of any of the representations and warranties made in
Section 3.13.

      SECTION 3.11. PRODUCTS LIABILITY.

Seller has no Liability and, to Seller's knowledge, there is no reasonable basis
for or any Claim pending, arising out of any injury to any Person or property as
a result of the ownership, possession, or use of any Seller Device.

      SECTION 3.12. PRODUCT WARRANTY.

Set forth on Schedule 3.12 are the standard forms of Product warranty of Seller
and any other warranty used by Seller. Since December 31, 2003 through the date
hereof, no Claims for breach of Product warranties to customers have been
received by Seller with the exception of standard product returns under Seller's
warranty policy that result in Product replacements. All Product replacements
arising under standard product returns or otherwise have been fulfilled.

      SECTION 3.13. OPERATIONS SINCE DECEMBER 31, 2003.

                                      -20-
<PAGE>

Except as set forth in Seller SEC Documents and as set forth on Schedule 3.10,
since December 31, 2003:

            (a) Seller has not incurred any material liability, acquired or
disposed of any business or assets, or entered into any Contract or other
transaction, involving an amount exceeding Two Hundred Thousand Dollars
($200,000) in any single case or One Million Dollars ($1,000,000) in the
aggregate; provided, however, that legal, independent auditor and insurance fees
are not included in these amounts.

            (b) Seller has not: (i) entered into a Specified Contract
inconsistent with past practices, (ii) adopted or entered into any new Employee
Benefit Plan, or modified or waived any right under any existing Employee
Benefit Plan or any Contract or award under any existing Employee Benefit Plan,
except for such modification or waiver effected to comply with Law or otherwise
in the ordinary course of business and consistent with past practices, (iii)
participated in any merger, consolidation, reorganization, share exchange,
business combination, recapitalization, reclassification of shares, stock split,
reverse stock split or similar transaction, (iv) acquired the business or any
bulk assets of any other Person, (v) changed any of its methods of accounting or
accounting practices in any respect except as required by Law or to comply with
changes in governing accounting principles, (vi) commenced or settled any
Proceeding, or (vii) recognized any union or labor organization as the
representative of Seller's employees.

      SECTION 3.14. REAL PROPERTY.

            (a) Seller does not own any Real Property or interest therein.

            (b) The Redwood City Lease is the only Real Property Contract
pursuant to which Seller leases, subleases or otherwise occupies any Real
Property, a true and correct copy of which has been made available to Parent.
Pursuant to the Redwood City Lease, Seller has validly existing and enforceable
leasehold, subleasehold or occupancy interests in the Real Property leased
thereunder.

      SECTION 3.15. ENVIRONMENTAL.

            (a) All activities and conduct of Seller, and to Seller's knowledge,
its predecessors, comply and have complied with all Environmental Laws, except
where the failure to have complied or be in compliance would not result in a
Material Adverse Effect. Neither Seller, nor to Seller's knowledge, any other
Person (including any of Seller's predecessors), has disposed of, released, or
threatened to release, any Substances on, under, in, from or about the Real
Property leased by Seller, that has subjected, or could reasonably be expected
to subject, Seller to any material Liability under any Environmental Law.
Neither Seller nor, to Seller's knowledge, any of Seller's predecessors, has
Handled, disposed of, or arranged for or permitted the disposal of, Substances
on any real property owned by third parties that has subjected, or could
reasonably be expected to subject, Seller to any material Liability under any
Environmental Law.

            (b) Seller has not received any notice, demand, letter, claim or
request for information alleging a violation of, or a material Liability under,
any Environmental Law, and there are no Proceedings, actions, orders, decrees,
injunctions or other claims, or, to the

                                      -21-
<PAGE>

knowledge of Seller, any threatened actions or claims, relating to or otherwise
alleging a material Liability under any Environmental Law.

      SECTION 3.16. INTELLECTUAL PROPERTY.

            (a) Schedule 2.01(c) sets forth an accurate and complete list of all
United States and foreign Trademarks and Patents and for each item of registered
or pending Purchased Intellectual Property, Schedule 2.01(c) includes the
following information: (i) current owner of record, (ii) application and
registration number, (iii) application and registrations dates, (iv) country,
and (v) expiration date.

            (b) Each item of the Purchased Intellectual Property is valid and
all necessary registration, maintenance and renewal fees relating to such
Purchased Intellectual Property have been paid through March 31, 2005.

            (c) Seller owns and has good and transferable title to, or possesses
adequate, legally enforceable and transferable rights to use under valid and
subsisting written Licenses, each item of Purchased Intellectual Property as
such item of Purchased Intellectual Property has been used or is being used, in
each case free and clear of any Liens other than the Permitted Liens, and each
item of Purchased Intellectual Property will be assigned to Acquisition Sub free
and clear of any Liens other than Tax Liens at the Closing.

            (d) The operations of Seller in conducting the Business (including
the performance of any Contract and the development, manufacture, marketing,
production, sale and distribution of Products) as conducted in the past or as
now conducted have not and do not, to the knowledge of Seller, (i) Infringe any
Intellectual Property of any Person, (ii) except pursuant to a Contract between
Seller and such Person, entitle any Person to any interest therein, or right to
compensation from Seller or any of its successors or assigns, by reason thereof,
or (iii) violate any applicable Law, except for such violations of applicable
Law as would not result in a Material Adverse Effect.

            (e) Except as set forth on Schedule 3.16(e) hereto, with respect to
Purchased Intellectual Property owned or licensed by Seller, Seller has the sole
right to: (i) bring actions for past, present and future infringement, dilution,
misappropriation or unauthorized use of the Purchased Intellectual Property,
injury to goodwill associated with the Purchased Intellectual Property, unfair
competition or trade practices violations or other violations of the Purchased
Intellectual Property; and (ii) receive all the proceeds from the foregoing set
forth in subsection (i) hereof, including, without limitation, licenses,
royalties, payments, claims, damages and proceeds of suit.

            (f) No Claim has been made, brought or, to Seller's knowledge, is
threatened by any Person, and Seller has not received notice of any Claim: (i)
alleging that any Purchased Intellectual Property or Products, or the use
thereof, infringes, violates, dilutes or misappropriates or has infringed,
violated, diluted or misappropriated (collectively "INFRINGES") the rights of
any Person; (ii) challenging the ownership, validity or enforceability of any
Purchased Intellectual Property; or (iii) alleging that the conduct of the
Business, including, without limitation, any products or services or the actual
or contemplated use, offer or provision

                                      -22-
<PAGE>

thereof by Seller, Infringes the rights of any Person. To Seller's knowledge,
neither the manufacture, use, sale or offer to sell of the Products Infringes
the rights of any Person.

            (g) Seller has not threatened or initiated any Claim against any
Person alleging that such Person Infringes any Purchased Intellectual Property,
and no such Claim is currently pending or being considered.

            (h) Seller has taken all commercially reasonable actions to protect
and preserve the security, confidentiality and value of all Purchased
Intellectual Property.

            (i) All personnel of Seller, including without limitation all
current and former officers, employees, agents, developers, consultants and
contractors, who have or have had access to, or have contributed to or
participated in the conception, reduction to practice, creation or development
of the Purchased Intellectual Property either: (i) are a party to a
"work-for-hire" agreement that has accorded and assigned to Seller all right,
title and interest in and to all Intellectual Property and all tangible and
intangible property created or developed, in whole or in part, by such Person;
or (ii) have executed appropriate instruments of assignment in favor of Seller
that have conveyed to Seller, and that contain a continuing obligation to convey
to Seller, all right, title and interest in and to all Intellectual Property and
all tangible and intangible property created and/or developed, in whole or in
part, by such Person.

            (j) Each current and former director, officer, employee, agent,
developer, consultant and contractor who has had or has access to, contributed
to or participated in the creation and/or development of any Intellectual
Property used in connection with the operation of the Business for, on behalf
of, or at the instruction of Seller, has executed a confidentiality and
nondisclosure agreement that protects the confidentiality of confidential
information and Intellectual Property used in connection with the operation of
the Business in favor of Seller.

            (k) Seller has not received any notice of a Claim nor, to Seller's
knowledge, is it reasonably likely that any of the Purchased Intellectual
Property is invalid, unenforceable, or misused.

            (l) Seller has not assigned, licensed, leased, sold, placed in
escrow or otherwise transferred, disposed of or released any interest which
Seller has or had in or to any Purchased Intellectual Property except for the
Sanofi Liens.

            (m) The Intellectual Property Communications will set forth all
Patent and Trademark due dates prior to March 31, 2005. The Patent and Trademark
Listing will set forth all Patents and Trademarks, the due dates of all actions
to be taken in order to maintain such Patents and Trademarks and all foreign
patent associates handling each Patent and Trademark.

      SECTION 3.17. CONTRACTS.

            (a) Seller has made available to Parent copies of all Contracts to
which Seller is a party or by which Seller is bound (collectively, the
"SPECIFIED CONTRACTS"), grouped into the following categories:

                                      -23-
<PAGE>

                  (i) Contracts for the purchase, license, lease and/or
maintenance of or rights in the Purchased Intellectual Property;

                  (ii) Contracts for the purchase or lease of Real Property or
otherwise concerning Real Property owned or used by Seller in the Business;

                  (iii) loan agreements, mortgages, notes, and guarantees and
other financing Contracts;;

                  (iv) employment, independent contractor, collective
bargaining, consulting and sales representative Contracts (excluding oral
Contracts with employees for "at will" employment);

                  (v) Contracts with suppliers, manufacturers, distributors or
other Persons in the supply, manufacture or distribution chain related to the
Business;

                  (vi) settlement or other Contracts related to any Assumed
Liabilities; and

                  (vii) other material Contracts, including Contracts for the
purchase, lease and/or maintenance of equipment for use in the Business, in each
case where the Contract requires payments in excess of $100,000 or where all
such Contracts require payments in excess of $500,000 in the aggregate.

            (b) With respect to each of the Specified Contracts to which Seller
is a party or is bound, Seller is not in Default thereunder and, to the
knowledge of Seller, none of the other parties to any Specified Contract is in
Default thereunder. Each Specified Contract to which Seller is a party or is
bound, is valid and enforceable against Seller and, to the knowledge of Seller,
against the other party or parties thereto, except where the failure to be valid
and enforceable would not result in a Material Adverse Effect. The execution and
delivery of this Agreement and consummation of the transactions contemplated
hereby will not result in the breach of, or create on behalf of any Person the
right to terminate or modify, any Specified Contract, except as set forth on
Schedule 3.25 hereto and the employment agreements between Seller and its
officers.

      SECTION 3.18. EMPLOYEES.

            (a) Seller is in compliance in all material respects with all Laws
respecting employment practices. Seller is not a party to or bound by any labor
Contract, collective bargaining agreement, letter of understanding, or any other
Contract, formal or informal, with any labor union or organization, nor is any
such Contract expired, in effect or being negotiated by or on behalf of Seller.
None of Seller's employees represented by any labor union or organization, nor
to Seller's knowledge, has Seller received written notice or other communication
that a union claims to represent any of the employees of Seller, and no union
has made such a claim to Seller within the last five years. No representations
have been made by Seller to any of its employees with respect to Acquisition
Sub's or Parent's intentions to employ Seller's employees; provided, however,
that during the pre-Closing period, Seller may advise its

                                      -24-
<PAGE>

employees that Parent and Acquisition Sub have no obligation to offer employment
to Seller's Business Employees.

            (b) There are no controversies pending or, to the knowledge of
Seller, threatened between Seller and any of its employees, except for such
controversies that have not had and could not reasonably be expected to have,
individually or in the aggregate, a Material Adverse Effect.

            (c) Seller is not engaged in any and has not been charged with any
unfair labor practice of any nature.

            (d) Since December 16, 1999, Seller has not effectuated (i) a "plant
closing" as defined in the Worker Adjustment and Retraining Notification Act
("WARN ACT"), affecting any site of employment or one or more facilities or
operating units within any site of employment or facility of Seller or (ii) a
"mass layoff" (as defined in the WARN Act) affecting any site of employment or
facility of Seller; nor has Seller been affected by any transaction or engaged
in layoffs or employment terminations sufficient in number to trigger
application of any state, local or foreign Law or regulation similar to the WARN
Act. To the knowledge of Seller, Seller's employees have not suffered an
"employment loss" (as defined in the WARN Act) in the previous ninety (90)
calendar days. Seller has complied in all material respects with its obligations
under the WARN Act, or any similar local, state or foreign Law and shall be
solely liable and responsible for any debt, obligation contribution or other
Liability arising from any failure by Seller to comply fully with the WARN Act
or any similar local, state or foreign Law.

            (e) Seller has not received written notice of the intent of any
federal, state, local or foreign Governmental or Regulatory Authority
responsible for the enforcement of labor or employment Laws to conduct an
investigation with respect to or relating to Seller and, to Seller's knowledge,
no such investigation is in progress.

      SECTION 3.19. EMPLOYEE BENEFIT PLANS.

            (a) Neither Seller nor any ERISA Affiliate is subject to (i) any
Liability for contributions or withdrawal Liability, contingent or otherwise,
within the meaning of Sections 4201 and 4204 of ERISA, under any the Employee
Benefit Plan maintained, sponsored, contributed to or required to be contributed
to by Seller or by any ERISA Affiliate, (ii) any Liens in connection with any
Employee Benefit Plan maintained, sponsored, contributed to or required to be
contributed to by Seller or by any ERISA Affiliate, or (iii) any Liability under
Section 4062, 4063, 4064 or 4069 of ERISA with respect to any Employee Benefit
Plan maintained, sponsored, contributed to or required to be contributed to by
Seller or by any ERISA Affiliate.

            (b) No Employee Benefit Plan is now, or ever was, (i) subject to
Title IV of ERISA or (ii) a Multiemployer Plan.

            (c) No Employee Benefit Plan provides benefits, including death or
medical benefits (whether or not insured), with respect to Business Employees
after retirement or other termination of service other than (i) coverage
mandated by applicable Law, (ii) death benefits or retirement benefits under any
"employee pension plan" (as such term is defined in Section 3(2) of ERISA) that
is qualified under Section 401(a) of the Code, (iii) benefits, the full cost of
which

                                      -25-
<PAGE>

is borne by the Business Employees (or his or her beneficiary), or (iv) by the
terms of an employment agreement.

      SECTION 3.20. TAXES.

            (a) Seller has filed all material Tax Returns required to be filed
by it. All such Tax Returns were correct and complete in all material respects.
All material Taxes owed by Seller (whether or not shown or required to be shown
on any Tax Return) have been paid. Seller is not currently the beneficiary of
any extension of time within which to file any Tax Return.

            (b) Seller has withheld and paid all Taxes required to have been
withheld and paid in connection with amounts paid or owing to any employee,
independent contractor, agent, representatives, suppliers, creditor,
stockholders or other Person and all Internal Revenue Service Forms W-2 and 1099
required with respect thereto have been properly completed and timely filed.

            (c) There is no material dispute or claim concerning any Tax
Liability of Seller either (A) claimed or raised by any authority in writing or
(B) as to which any of the directors and officers of Seller (and employees
responsible for Tax matters) of Seller has knowledge based upon personal contact
with any agent of such authority.

            (d) Seller has not waived any statute of limitations in respect of
Taxes or agreed to any extension of time with respect to a Tax assessment or
deficiency.

            (e) The unpaid Taxes of Seller (A) did not, as of the date of the
Latest Balance Sheet, exceed the reserve for Tax liability (rather than any
reserve for deferred Taxes established to reflect timing differences between
book and Tax income) set forth on the face of the Latest Balance Sheet (rather
than in any notes thereto) and (B) do not exceed that reserve as adjusted for
the passage of time in accordance with the past custom and practice of Seller in
filing their Tax Returns.

            (f) None of the Assumed Liabilities is an obligation to make a
payment that is not deductible under Section 280G of the Code, or would
constitute compensation in excess of the limitations set forth in Section 162(m)
of the Code.

            (g) Seller is not a party to, is not bound by, and has no Liability
under any Tax sharing agreement or similar Contract. Seller (A) is not, and has
never been, a member of an affiliated group of corporations, within the meaning
of Section 1504 of the Code and (B) has no Liability for Taxes of any Person
under Treasury Regulation Section 1.1502-6 (or any similar provision of state,
local or foreign Law), as a transferee or successor, by Contract or otherwise.

      SECTION 3.21. PROCEEDINGS AND JUDGMENTS.

There is no pending Proceeding, and, to the knowledge of Seller, no Person has
threatened to commence any Proceeding that involves Seller or any of the
Purchased Assets, which has had or would reasonably be expected to have a
Material Adverse Effect. Seller is not subject to any outstanding and
unsatisfied judgment except for the Sanofi Liens.

                                      -26-
<PAGE>

      SECTION 3.22. INSURANCE.

Schedule 3.22 attached hereto sets forth a complete and accurate list, of
Seller's insurance as of the date hereof (including policy number, amount and
type of coverage) maintained on its respective properties and assets (including
the Purchased Assets) and with respect to its employees and representatives,
directors and officers, product liability and business and which, in the
reasonable judgment of Seller, covers risks customarily insured by Persons who
engage in activities similar to the Business ("INSURANCE POLICIES"). Such
insurance includes fire, casualty, business interruption and flood coverage in
respect of all of the Purchased Assets owned or leased by Seller. To Seller's
knowledge, all such insurance policies are valid, binding and enforceable in
accordance with their terms against the respective insurers, except as
enforcement may be limited by applicable bankruptcy, insolvency, reorganization,
moratorium or similar Laws affecting creditor's rights generally. To Seller's
knowledge, no insurer is the subject of insolvency Proceedings. Seller has
notified its respective insurance carriers of all litigation, claims and facts
that could reasonably give rise to a claim, all of which are set forth on
Schedule 3.22 attached hereto. Except as set forth on Schedule 3.22, Seller has
received no written notices from its insurance carrier disclaiming coverage or
defending a reservation of rights clause as to any of such notifications.

      SECTION 3.23. EFFECT OF AGREEMENT; INAPPLICABILITY OF ANTI-TAKEOVER
STATUTES.

            (a) Seller has the requisite corporate power and authority to
execute, deliver and perform this Agreement and each of the documents,
agreements and instruments to be executed, delivered and performed by it in
connection with this Agreement (collectively the "SELLER COLLATERAL DOCUMENTS"),
and Seller has all requisite power and authority to transfer the Purchased
Assets to Acquisition Sub.

            (b) The execution, delivery and performance of this Agreement and
each of the Collateral Documents by Seller, and the consummation of the
transactions contemplated by this Agreement and thereby, have been duly
authorized by all necessary corporate action on the part of Seller, other than
the Required Seller Stockholder Vote, and requires no further authorization or
consent by Seller, Seller's stockholders or any other Person other than the
approval thereof by Seller's stockholders. This Agreement and the Seller
Collateral Documents have been duly executed and delivered by Seller and,
subject to receipt of approval by Seller's stockholders assuming due execution
and delivery by Parent and Acquisition Sub, constitute the legal, valid and
binding obligations of Seller enforceable against Seller in accordance with
their terms.

            (c) Seller is not subject to any "moratorium", "control share",
"fair price" or other anti-takeover laws and regulations of any state
(collectively the "TAKEOVER LAWS") that would affect this Agreement or the
transactions contemplated hereby. Seller's board of directors has approved this
Agreement and the transactions contemplated hereby for the purpose of such
Takeover Laws.

      SECTION 3.24. ASSUMED CONTRACTS.

                                      -27-
<PAGE>

Since January 1, 2004, there has been no termination, cancellation or material
curtailment of any Assumed Contract with any supplier or group of affiliated
suppliers nor has there been any written notice of intent to so terminate,
cancel or materially curtail.

      SECTION 3.25. REQUIRED NON-GOVERNMENTAL CONSENTS.

Schedule 3.25 sets forth those Assumed Contracts requiring a Consent by any
Person as a result of the execution, delivery or performance of this Agreement
by Seller or the consummation of the transactions contemplated hereby (the
"REQUIRED NON-GOVERNMENTAL CONSENTS").

      SECTION 3.26. SOLVENCY

            (a) Seller is Solvent for all purposes as that term is defined
herein and the transactions contemplated by this Agreement will not render
Seller Insolvent;

            (b) By entering into the transactions contemplated by this
Agreement, Seller does not intend to incur, and does not believe that it will
incur, debts that will be beyond Seller's ability to pay as such debts mature;
and

            (c) Seller is not entering into the transactions contemplated by
this Agreement or incurring any obligation pursuant to this Agreement with the
intent to hinder, delay, or defraud any creditor to which Seller is or may
become indebted.

      SECTION 3.27. FINISHED GOODS INVENTORY.

            (a) The finished goods inventory of Seller consists of items
manufactured in accordance with applicable requirements of the QSR and ISO
13485, subject to any expiration dates, are useable and salable in accordance
with the Purchased PMA and the Purchased CE Marking.

            (b) All Products in Inventory have a shelf life designation that is
valid and expires according to Schedule 2.01(d) attached hereto.

      SECTION 3.28. VOTE REQUIRED.

The affirmative vote of the holders of a majority of the shares of Seller Common
Stock outstanding on the record date and entitled to vote at Seller
Stockholders' Meeting (the "REQUIRED SELLER STOCKHOLDER VOTE") is the only vote
of the holders of any class or series of Seller's capital stock necessary to
adopt this Agreement, approve or consummate any of the other transactions
contemplated by this Agreement.

      SECTION 3.29. NON-CONTRAVENTION; CONSENTS.

Subject to the adoption of this Agreement by the holders of Seller Common Stock,
neither (i) the execution, delivery or performance by Seller of this Agreement,
nor (ii) the consummation by Seller of the transactions contemplated by this
Agreement, will directly or indirectly (with or without notice or lapse of
time):

                                      -28-
<PAGE>

            (a) contravene, conflict with or result in a violation of any of the
provisions of the certificate of incorporation or bylaws of Seller, or any
resolution adopted by the stockholders, the board of directors or any committee
of the board of directors of Seller, which resolution has not been superseded;

            (b) contravene, conflict with or result in a violation of, or give
any Governmental or Regulatory Authority or other Person the right to challenge
the transactions contemplated by this Agreement or to exercise any remedy or
obtain any relief under, any Law or any Judgment to which Seller, or any of the
Purchased Assets, is subject;

            (c) contravene, conflict with or result in a violation of any of the
terms or requirements of, or give any Governmental or Regulatory Authority the
right to revoke, withdraw, suspend, cancel, terminate or modify, any material
Governmental Authorization that is held by Seller that relates to the Business
or to any of the Purchased Assets;

            (d) contravene, conflict with or result in a violation or breach of,
result in a Default under or require Consent under, any provision of any
Specified Contract to which Seller is a party or is bound, or give any Person
the right to (i) declare a Default (or give rise to any right of termination,
amendment, cancellation or acceleration) or exercise any remedy under any such
Specified Contract, (ii) a rebate, chargeback, penalty or change in delivery
schedule under any such Specified Contract, (iii) accelerate the maturity or
performance of any such Specified Contract, or (iv) cancel, terminate or modify
any term of such Specified Contract; or

            (e) result in the imposition or creation of any Lien upon or with
respect to any Purchased Asset.

Except as may be required by the Exchange Act and the DGCL, Seller was not, or
is not, required to make any filing with or give any notice to, or to obtain any
Consent from, any Governmental or Regulatory Authority in connection with (i)
the execution, delivery or performance of this Agreement by Seller, or (ii) the
consummation by Seller of the transactions contemplated by this Agreement.

      SECTION 3.30. FAIRNESS OPINION.

Seller's board of directors has received the written opinion of First Albany
Capital Inc., financial advisor to Seller, dated as of the date hereof, to the
effect that as of such date the Consideration is fair to Seller from a financial
point of view. Seller has furnished a true and correct copy of said written
opinion to Parent.

      SECTION 3.31. FINANCIAL ADVISORY FEES AND AGREEMENTS.

            (a) Except as set forth on Schedule 3.31(a), no broker, finder or
investment banker is entitled to any brokerage, finder's or other fee or
commission in connection with any of the other transactions contemplated by this
Agreement based upon arrangements made by or on behalf of Seller. Seller has
made available to Parent accurate and complete copies of all Contracts under
which any fees, commissions and other amounts have been paid or may become
payable and all indemnification and other agreements related to the engagement
of First Albany Capital Inc.

                                      -29-
<PAGE>

            (b) Except as set forth on Schedule 3.31(a), Seller does not have
any obligation or Liability of any nature under, or with respect to, any
brokerage agreement, finders agreement, placement agency agreement, financial
advisory agreement, underwriting agreement or similar agreement.

      SECTION 3.32. ASSUMED CONTRACTS; CUSTOMER CLAIMS.

Each of the Assumed Contracts is valid and enforceable against Seller, and to
the knowledge of Seller, against the other party or parties thereto. Seller has
made available to Parent true and complete copies of such Assumed Contracts.
There are no existing material Defaults of Seller under any such Assumed
Contract or, to the knowledge of Seller, any other parties thereto. There are no
obligations of Seller to any other party to an Assumed Contract other than those
obligations of Seller that are expressly provided for in such Assumed Contract.
To the knowledge of Seller, there are no valid grounds for a Claim against
Seller by any customer or former customer of Seller for fraud.

      SECTION 3.33. SUFFICIENCY OF PURCHASED ASSETS.

The Purchased Assets used in the operation of the Business are sufficient for
the operation of the Business as was operated in the ordinary course. Except for
the Excluded Assets, there are no assets used in the conduct of the Business,
other than the Purchased Assets.

      SECTION 3.34. SECTION 203 OF THE DGCL NOT APPLICABLE.

Section 203 of the DGCL is not applicable to Seller.

      SECTION 3.35. FULL DISCLOSURE.

No representation or warranty by Seller contained in this Agreement or pursuant
hereto and no statement contained in any document (including financial
statements and certificates), or other writings furnished or to be furnished by
Seller to Parent or Acquisition Sub or any of their Representatives (excluding
financial forecasts, and other forward looking projections or information)
pursuant to the provisions hereof or identified or referred to in the schedules
hereto, when taken as a whole, contains untrue statement of material fact or
omits any material fact necessary, in light of the circumstances under which it
was made, in order to make the statements herein or therein not false or
misleading.

                                    ARTICLE 4
                        REPRESENTATIONS AND WARRANTIES OF
                           PARENT AND ACQUISITION SUB

Parent and Acquisition Sub hereby jointly and severally represent and warrant to
Seller as follows:

      SECTION 4.01. EXISTENCE AND POWER.

                                      -30-
<PAGE>

Parent is a corporation duly organized and validly existing and in good standing
under the Laws of the State of Delaware. Acquisition Sub is a limited liability
company duly formed, active and in good standing under the Laws of the State of
Delaware.

      SECTION 4.02. AUTHORIZATION.

Parent and Acquisition Sub each have the requisite power and authority to
execute, deliver and perform this Agreement and each of the documents,
agreements and instruments to be executed, delivered and performed by either of
them in connection with this Agreement (collectively the "PURCHASER COLLATERAL
DOCUMENTS"). The execution, delivery and performance by Parent and Acquisition
Sub of this Agreement and each of the Purchaser Collateral Documents, and the
consummation of the transactions contemplated by this Agreement and thereby have
been duly authorized by all necessary action on the part of Parent and
Acquisition Sub and, except as set forth on Schedule 4.02, requires no other
authorization or consent by Parent, Acquisition Sub or any other Person.

      SECTION 4.03. ENFORCEABILITY.

This Agreement and the Purchaser Collateral Documents have been duly executed
and delivered by Parent and Acquisition Sub and (assuming due execution and
delivery by Seller) constitute the legal, valid and legally binding obligations
of Parent and Acquisition Sub, enforceable against them in accordance with their
terms.

      SECTION 4.04. NONCONTRAVENTION.

Neither the execution, delivery and performance by Parent and Acquisition Sub of
this Agreement, nor the consummation by Parent and Acquisition Sub of the
transactions contemplated hereby, do or will (a) contravene, conflict with or
result in a violation of any of the provisions of the certificate of
incorporation or by-laws of Parent or the certificate of formation or operating
agreement of Acquisition Sub or with any resolution adopted by the stockholders,
members, boards of directors, any committee of the boards of directors or
managers of Parent or Acquisition Sub, which resolution has not been superseded,
(b) contravene, conflict with or result in a violation of, or give any
Governmental or Regulatory Authority or other Person the right to challenge the
transactions contemplated by this Agreement or to exercise any remedy or obtain
any relief under any Law or any Judgment to which Parent or Acquisition Sub is
subject, (c) violate any Law applicable to Parent or Acquisition Sub, or (d)
except as set forth on Schedule 4.04 require any Consent or other action by any
Person under any agreement or other instrument binding upon Parent or
Acquisition Sub.

      SECTION 4.05. FINANCIAL ABILITY.

Parent has sufficient funds to cause Acquisition Sub to pay the Consideration in
cash in accordance with Section 2.04.

      SECTION 4.06. NO BROKERS.

                                      -31-
<PAGE>

There is no investment banker, broker, finder or other intermediary who has been
retained by or is authorized to act on behalf of Parent or Acquisition Sub who
might be entitled to any fee or commission upon the consummation of the
transactions contemplated by this Agreement.

      SECTION 4.07. RESALE AND MANUFACTURING.

In accordance with and subject to the terms and conditions of this Agreement, on
the Closing Date, Acquisition Sub shall purchase the Inventory for resale
purposes. Parent is a qualified manufacturer in the Commonwealth of
Pennsylvania.

                                    ARTICLE 5
                      PRE-CLOSING COVENANTS OF THE PARTIES

      SECTION 5.01. ACCESS AND INVESTIGATION.

            (a) During the period from the date of this Agreement through the
Closing Date (the "PRE-CLOSING PERIOD"), Seller shall: (a) provide Parent and
Acquisition Sub and their Representatives with reasonable access to Seller's
Representatives, personnel and Purchased Assets and to all existing books,
records, Tax Returns, internal work papers and other documents and information
relating to Seller and the Purchased Assets; (b) provide Parent and Acquisition
Sub and their Representatives with such copies of the existing books, records,
Tax Returns, internal work papers and other documents and information relating
to Seller, and with such additional financial, operating and other data and
information regarding Seller and its financial condition, as Parent or
Acquisition Sub may reasonably request; and (c) fully cooperate with Parent and
Acquisition Sub in their reasonable investigation of the Purchased Assets.
Without limiting the generality of the foregoing, during the Pre-Closing Period,
Seller shall furnish promptly to Parent (i) a copy of each report, schedule,
registration statement and other document filed or furnished by Seller during
the Pre-Closing Period with the SEC, (ii) any material notice, document or other
communication sent or proposed to be sent by or on behalf of Seller by any party
to any Assumed Contract or sent to Seller by any party to any Assumed Contract
(other than any communication that relates solely to routine commercial
transactions between Seller and the other party to any such Assumed Contract and
that is of the type sent in the ordinary course of business and consistent with
past practices); and (iii) all other information existing concerning the
Business, properties and personnel as Parent or Acquisition Sub may reasonably
request; it being understood that, with respect to the information referenced in
this Section 5.01(a), Seller shall not be required to create information for
Parent and Acquisition Sub that it would not normally create in the ordinary
course of business.

            (b) Seller shall during the Pre-Closing Period give prompt written
notice to Parent and Acquisition Sub, and Parent and Acquisition Sub shall
during the Pre-Closing Period give prompt written notice to Seller, of:

                  (i) the discovery by such party of any event, condition, fact
or circumstance that occurred or existed on or prior to the date of this
Agreement and that caused or constitutes an inaccuracy in any representation or
warranty made by such party in this Agreement;

                                      -32-
<PAGE>

                  (ii) any event, condition, fact or circumstance that occurs,
arises or exists after the date of this Agreement and that would cause or
constitute a material inaccuracy as of the date hereof or as of the Closing Date
in any representation or warranty made by such party in this Agreement;

                  (iii) the failure by it to comply with or satisfy in any
material respect any covenant, condition or agreement to be complied with or
satisfied by it under this Agreement;

                  (iv) the occurrence of an event or circumstance that could be
reasonably expected to make the timely satisfaction of any of the conditions set
forth in Article 6 impossible or unlikely or that has had or would reasonably be
expected to have a Material Adverse Effect; or

                  (v) the commencement of any litigation or Proceeding against
or affecting this Agreement.

      SECTION 5.02. CONDUCT PENDING CLOSING.

            (a) During the Pre-Closing Period:

                  (i) Seller shall conduct its businesses and operations in
compliance in all material respects with all applicable Law (including the WARN
Act) and with the requirements of all Specified Contracts;

                  (ii) Seller shall provide full cooperation and shall take
whatever actions necessary to effect the transfer as of the Closing Date of all
of Seller's Documentation and Foreign Documentation to Acquisition Sub;

                  (iii) Seller shall keep in full force, or renew at appropriate
levels of coverage upon expiration, applicable insurance policies;

                  (iv) Seller will close all outstanding Product complaints
received prior to the Closing Date, provided that if such complaints require
return of the Product and such Product has not been returned at least ten (10)
Business Days prior to the Closing Date, Seller shall have no obligation to
close such complaints; and

                  (v) Seller shall promptly notify Parent and Acquisition Sub of
any notice or other communication from any Person alleging that the Consent of
such Person is or may be required in connection with any of the transactions
contemplated by this Agreement.

            (b) During the Pre-Closing Period, Seller shall not (without the
prior written consent of Parent):

                  (i) (A) declare, accrue, set aside or pay any dividend on, or
make any other distribution (whether in cash, securities or other property) in
respect of, any of its outstanding capital stock , (B) split, combine or
reclassify any of its outstanding capital stock or other equity interests or
issue or authorize the issuance of any other securities in respect of, in

                                      -33-
<PAGE>

lieu of or in substitution for shares of its outstanding capital stock or other
equity interests (other than the issuance of Seller Common Stock pursuant to the
valid exercise of options to acquire Seller Common Stock outstanding as of the
date of this Agreement), or (C) purchase, redeem or otherwise acquire any shares
of outstanding capital stock or any rights, warrants or options to acquire any
such shares

                  (ii) amend or permit the adoption of any amendment to its
certificate of incorporation or bylaws, or effect or become a party to any
merger, consolidation, share exchange, business combination, amalgamation,
recapitalization, reclassification of shares, stock split, reverse stock split,
division or subdivision of shares, consolidation of shares or similar
transaction;

                  (iii) form any subsidiary or directly or indirectly acquire
any equity or other interest in, or make any other investment in or capital
contribution to, any other entity;

                  (iv) except for capital expenditures relating to the Redwood
City Facility that Seller reasonably believes will be reimbursed by insurance,
make any single capital expenditure in excess of $25,000 or, when added to all
other capital expenditures made by Seller during the Pre-Closing Period, exceed
a total of $75,000;

                  (v) except as otherwise permitted by this Section 5.02, enter
into or become bound by, or permit any of the Purchased Assets to become bound
by, any material Contract, or amend or terminate, or waive or exercise any
material right or remedy under, any material Contract, in each case other than
in the ordinary course of business and consistent with past practices;

                  (vi) acquire, lease or license any right or other asset from
any other Person or sell or otherwise dispose of, or lease or license, any right
or other asset, including without limitation, any Purchased Intellectual
Property to any other Person, except in each case for assets acquired, leased,
licensed or disposed of by Seller in the ordinary course of business and
consistent with past practices;

                  (vii) dispose of or permit to lapse any material rights to the
use of any Purchased Intellectual Property, or dispose of or disclose to any
Person other than Representatives of Parent and Acquisition Sub any material
trade secret, formula, process or know-how related to the Business not
theretofore a matter of public knowledge, except in each case in ordinary course
of business and consistent with past practices;

                  (viii) lend money to any Person, or incur or guarantee any
indebtedness, including any additional borrowings under any existing lines of
credit (except that Seller may make routine borrowings and advancement of
expenses in the ordinary course of business and consistent with past practices);

                  (ix) except as required to comply with applicable Law,
establish, adopt or amend any Employee Benefit Plan, pay, commit to pay or
accelerate the payment of any bonus or make, commit to make or accelerate any
profit-sharing or similar payment to, or increase or commit to increase the
amount of the wages, salary, commissions, fringe benefits, severance, insurance
or other compensation or remuneration payable to, any of its directors,

                                      -34-
<PAGE>

officers, employees or consultants; provided, however, that nothing in this
Section 5.02(b)(ix) shall prevent Seller from paying (or committing to pay)
consideration in the aggregate amount of Three Million Dollars ($3,000,000)
pursuant to any Contracts with Business Employees relating to termination,
employment, retention, change-in-control or severance;

                  (x) other than in the ordinary course of business consistent
with past practice, change any of its warranty policies in any material respect;

                  (xi) make or rescind any material Tax election or settle or
compromise any material Tax Liability of Seller;

                  (xii) (A) commence or settle any material Proceeding, or (B)
except as set forth on Schedule 3.10, pay, discharge or satisfy any material
Claims, Liabilities or obligations (absolute, accrued, asserted or unasserted,
contingent or otherwise);

                  (xiii) except as provided in Section 5.04(b) herein, adopt or
enter into a , merger, consolidation or any Contract relating to an Acquisition
Proposal;

                  (xiv) permit any material insurance policy naming it as a
beneficiary or a loss payable payee to be cancelled or terminated;

                  (xv) take any action that could be reasonably expected to
result in any of the conditions set forth in Section 6.01 not being satisfied;

                  (xvi) except in connection with the liquidation and
dissolution of Seller after the Closing Date, enter into any material
transaction or take any other material action outside the ordinary course of
business and inconsistent with past practices;

                  (xvii) acquire, lease or enter into any Contract to acquire or
lease any Real Property;

                  (xviii) amend, modify, extend, or enter into any collective
bargaining agreement or other Contract with any union or labor organization
representing any employees of Seller; or

                  (xix) agree or commit to take any of the actions described in
clauses (i) through (xviii) of this Section 5.02(b).

            (c) Seller shall provide Parent with a copy of, and substantively
and timely respond on or before the Closing Date to, all outstanding Patent and
Trademark actions, requests, notifications, or communications from the PTO (the
"INTELLECTUAL PROPERTY COMMUNICATIONS") and, within five (5) Business Days
following the receipt thereof, any similar items arising after the date hereof
which, but for the fact that they arose after the date hereof, would be
classified as an Intellectual Property Communication, unless the deadline for
such response is more than thirty (30) calendar days after the Closing Date. Any
substantive response to be made pursuant to this Section 5.02(c) shall be first
delivered to Parent for its approval (which shall not be unreasonably withheld)
before any such substantive response is sent to the PTO. If the approval of
Parent is not received before such time as Seller would have to send such
response in order for

                                      -35-
<PAGE>

it to be timely, Parent shall be deemed to have approved such response.
Regardless of any explicit or deemed approval by Parent, under no circumstance
shall a substantive response include an abandonment of the respective
Intellectual Property. Seller shall not request any extension of any response
deadline without the prior consent of Parent.

            (d) Within two (2) Business Days from the date hereof, Seller will
provide Parent with a current listing of the Intellectual Property
Communications having due dates on or before March 31, 2005. On or before
January 7, 2005, Seller will provide Parent with a current listing of the Patent
and Trademark due dates for any actions required to be taken in order to
maintain such Patents and Trademarks as well as a list specifying the foreign
patent associates handling each Patent or Trademark (the "PATENT AND TRADEMARK
LISTING").

      SECTION 5.03. CASUALTY PRIOR TO CLOSING.

In the event that, prior to Closing, any Purchased Asset shall be damaged by
fire, casualty or any other cause resulting in Seller not being able to satisfy
one or more closing conditions, Seller shall promptly notify Parent, which shall
then have the option to waive such closing condition or terminate this
Agreement. If Parent elects to waive the closing condition, Parent shall have
the option to (i) have Seller deliver the insurance proceeds to Acquisition Sub
at Closing or require Seller to assign the insurance proceeds at Closing to
Acquisition Sub if such proceeds have not yet been received, which in either
case shall become Purchased Assets or (ii) if the damaged assets can be restored
or replaced prior to Closing, direct Seller to use the insurance proceeds prior
to the Closing to restore or replace the Purchased Assets that were lost or
damaged. If the insurance proceeds are delivered or assigned to Acquisition Sub
at Closing, any liabilities related to the restoration or replacement of the
damaged assets shall become Assumed Liabilities. If Seller has restored or
replaced the damaged assets prior to Closing but has not yet received the
insurance proceeds, such proceeds shall become Excluded Assets.

      SECTION 5.04. NO SOLICITATION.

            (a) Seller shall not nor shall it authorize (and shall use its best
efforts not to permit) any Affiliate, officer, director, manager or employee of,
or any investment banker, attorney or other advisor or representative
(collectively, "REPRESENTATIVES") of Seller to (i) solicit or initiate any
inquiries relating to, or the submission of, any Acquisition Proposal, (ii)
participate in any discussions or negotiations regarding any Acquisition
Proposal, or in connection with any Acquisition Proposal, or furnish to any
Person any non-public information or data with respect to or provide access to
the properties of Seller, or take any other action in order to facilitate the
making of any proposal that constitutes an Acquisition Proposal or (iii) enter
into any agreement with respect to any Acquisition Proposal or approve or
resolve to approve any Acquisition Proposal; provided, that notwithstanding
anything to the contrary contained in this Agreement, nothing contained in this
Section 5.04 or any other provision hereof shall prohibit Seller or Seller's
board of directors from taking and disclosing to Seller's stockholders a
position with respect to a tender or exchange offer by a third party pursuant to
Rules 14d-9 and 14e-2 promulgated under the Exchange Act, provided that Seller
may not, except as permitted by Section 5.04(b), withdraw or modify, or propose
to withdraw or modify, the Seller Board Recommendation or approve or recommend,
or propose to approve or recommend any Acquisition Proposal, or enter into any
agreement with respect to any

                                      -36-
<PAGE>

Acquisition Proposal. Upon execution of this Agreement, Seller will immediately
cease any existing activities, discussions or negotiations with any Person
conducted heretofore with respect to any of the foregoing. Notwithstanding the
foregoing, prior to the Closing Date, Seller may furnish nonpublic information
or data concerning, or provide access to, its businesses, properties or assets
to any Person or "group" (as defined in the Exchange Act and the rules
promulgated thereunder) and may negotiate and participate in discussions and
negotiations with such Person or group concerning an Acquisition Proposal,
provided that such Person or group shall have entered into a confidentiality
agreement, the confidentiality provisions of which shall be no more favorable to
such third party than those provided for in the Confidentiality Agreement
(provided that such confidentiality agreement must permit Seller to disclose to
Parent all of the information required to be disclosed by Seller to Parent by
this Section 5.04) if:

                  (i) such Person or group has submitted an Acquisition Proposal
that the Board has determined in good faith is, or would reasonably be expected
to result in, a Superior Proposal (as defined below);

                  (ii) Seller's board of directors has determined in good faith,
after consultation with outside legal counsel to Seller, such action is required
to discharge the board's fiduciary duties to Seller's stockholders under
applicable Law; and

                  (iii) Seller has notified Parent in writing of its intention
to engage in such discussions or negotiations or to provide such confidential
information not less than the third (3rd) Business Day prior to so doing.

Seller will promptly (but in no case later than twenty-four (24) hours after
receipt thereof) notify Parent in writing of the existence of any proposal,
discussion, negotiation or inquiry received by Seller regarding any Acquisition
Proposal, and Seller will promptly (but in no case later than twenty-four (24)
hours after receipt thereof) communicate to Parent the terms of any proposal,
discussion, negotiation or inquiry which it may receive regarding any
Acquisition Proposal (and will promptly provide to Parent copies of any written
materials (including e-mails) received by Seller or its Representatives in
connection with such proposal, discussion, negotiation or inquiry) and the
identity of the party making such proposal or inquiry or engaging in such
discussion or negotiation. Seller will promptly provide to Parent any non-public
information concerning Seller provided to any other Person in connection with
any Acquisition Proposal which was not previously provided to Parent. Seller
will, when reasonably requested by Parent, keep Parent informed on a prompt
basis of the status and details of any such Acquisition Proposal and of any
amendments or proposed amendments to any Acquisition Proposal and of the status
of any discussions or negotiations relating to any Acquisition Proposal.

            (b) Except as set forth in this Section 5.04(b), neither the board
of directors of Seller nor any committee thereof shall (i) withdraw or modify,
or propose to withdraw or modify, in a manner adverse to Parent or Acquisition
Sub, the Seller Board Recommendation, (ii) approve or recommend, or propose to
approve or recommend, any Acquisition Proposal or (iii) enter into any agreement
with respect to any Acquisition Proposal (other than a confidentiality agreement
entered into in accordance with Section 5.04(a)). Notwithstanding the foregoing,
subject to compliance with the provisions of this Section 5.04, prior to the
Closing Date, Seller's board of directors, after consultation with outside legal
counsel, may withdraw or

                                      -37-
<PAGE>

modify the Seller Board Recommendation, approve or recommend a Superior
Proposal, or propose to enter into or enter into an agreement with respect to a
Superior Proposal, if the board determines in good faith after consultation with
outside legal counsel that, such action would otherwise be required to discharge
the board's fiduciary duties to Seller's stockholders under applicable Law in
the absence of the limitations on such action under this Agreement, provided
that in each case, Seller has given Parent written notice at least three (3)
Business Days in advance of such action that the board of directors of Seller
has received a Superior Proposal which it intends to accept, specifying the
material terms and conditions of such Superior Proposal and identifying the
Person making such Superior Proposal. Notwithstanding any provision of this
Agreement, the board of directors of Seller shall not be prohibited from making
any disclosure that, in the good faith judgment of the board (made after
consultation with outside legal counsel), is necessary to satisfy its fiduciary
duty of disclosure.

            (c) Nothing in this Section 5.04, and no action taken by the board
of directors of Seller pursuant to this Section 5.04, will (i) permit Seller to
enter into any agreement providing for any transaction contemplated by an
Acquisition Proposal for as long as this Agreement remains in effect, except as
expressly set forth herein, or (ii) affect in any manner any other obligation of
Seller under this Agreement.

            (d) For purposes of this Agreement, "ACQUISITION PROPOSAL" shall
mean any bona fide offer, proposal or other indication of interest regarding any
of the following (other than the transactions provided for in this Agreement
involving Seller): (i) any merger, consolidation, share exchange,
recapitalization, business combination or other similar transaction involving
Seller; (ii) any sale, lease, exchange, mortgage, pledge, transfer or other
disposition of all or a significant portion of the assets or non-cash assets of
Seller (other than the Johnson & Johnson Claim), taken as a whole, in a single
transaction or series of related transactions; (iii) any purchase of or tender
offer or exchange offer for ten percent (10%) percent or more of the outstanding
shares of capital stock of Seller, or the filing of a registration statement
under the Securities Act in connection therewith; or (iv) any public
announcement of a proposal, plan or intention to do any of the foregoing or any
agreement to engage in any of the foregoing. For purposes of this Agreement,
"SUPERIOR PROPOSAL" shall mean an Acquisition Proposal not solicited in
violation of this Agreement that is on terms which the board of directors of
Seller determines in good faith to be more favorable from a financial point of
view to Seller or Seller's stockholders, as the case may be, than terms of the
transactions contemplated by this Agreement (after consultation with Seller's
outside financial advisor), and with respect to which the board of directors of
Seller has determined in good faith (after consultation with Seller's outside
financial advisor) that financing, to the extent required, is reasonably capable
of being obtained; provided, however, that for purposes of this definition,
"Acquisition Proposal" shall be deemed to refer only to a transaction involving
a majority of the outstanding voting securities of Seller or a majority,
substantially all, or all of the assets or non-cash assets of Seller (other than
the Johnson & Johnson Claim).

            (e) Seller agrees not to release or permit the release of any Person
from, or to waive or permit the waiver of any provision of, any confidentiality,
"standstill" or similar Contract to which Seller is a party or under which
Seller has any rights, and will use its best efforts to enforce or cause to be
enforced each such Contract at the request of Parent. Seller also will promptly
request each Person that has executed a confidentiality agreement in connection

                                      -38-
<PAGE>

with its consideration of a possible Acquisition Proposal or equity investment
to return all confidential information heretofore furnished to such Person by or
on behalf of Seller.

      SECTION 5.05. STOCKHOLDER APPROVAL; PROXY STATEMENT.

            (a) Seller shall, as soon as practicable following the date hereof,
prepare and file with the SEC a preliminary Proxy Statement and shall use
commercially reasonable efforts to respond to any comments of the SEC or its
staff and to cause a definitive Proxy Statement to be mailed to Seller's
stockholders, as promptly as practicable. Seller shall notify Parent promptly of
the receipt of any comments from the SEC or its staff and of any request by the
SEC or its staff for amendments or supplements to the Proxy Statement or for
additional information and will supply Parent with copies of all correspondence
between Seller or any of its Representatives, on the one hand, and the SEC or
its staff, on the other hand, with respect to the Proxy Statement. Seller shall
give Parent an opportunity to comment on any correspondence with the SEC or its
staff or any proposed material to be included in the Proxy Statement prior to
transmission to the SEC or its staff and shall not transmit any such material to
which Parent reasonably objects. If at any time prior to Seller's Stockholders'
Meeting there shall occur any event that should be set forth in an amendment or
supplement to the Proxy Statement, Seller shall promptly prepare such an
amendment or supplement and after obtaining the consent of Parent to such
amendment or supplement, shall promptly transmit such amendment or supplement to
Seller's stockholders.

            (b) Seller shall as promptly as possible following the date that the
Proxy Statement is cleared by the SEC take all action necessary under all
applicable Law to call, give notice of and hold a meeting of the holders of
Seller Common Stock to vote on the approval and adoption of this Agreement and
the transactions contemplated hereby (the "SELLER STOCKHOLDERS' MEETING").
Seller shall ensure that all proxies solicited in connection with the Seller
Stockholders' Meeting are solicited in compliance with all applicable Law.

            (c) Once the Seller Stockholders' Meeting has been called and
noticed, Seller shall not postpone or adjourn (other than for the absence of a
quorum and then only to the next possible future date) the Seller Stockholders'
Meeting without Parent's consent. Subject to Section 5.04: (A) Seller shall
include the Seller Board Recommendation in the Proxy Statement; and (B) the
Seller Board Recommendation shall not be withdrawn or modified in a manner
adverse to Parent or Acquisition Sub, and no resolution by the board of
directors of Seller or any committee thereof to withdraw or modify the Seller
Board Recommendation in a manner adverse to Parent or Acquisition Sub shall be
adopted or proposed. The board of directors of Seller shall submit this
Agreement to the holders of Seller Common Stock, whether or not the board of
directors of Seller at any time changes, withdraws or modifies the Seller Board
Recommendation. Subject to Section 5.04, Seller shall solicit from the holders
of Seller Common Stock proxies in favor of the Agreement and shall take all
other action necessary or advisable to secure the vote or consent of the holders
of Seller Common Stock required by the DGCL and the certificate of incorporation
and bylaws of Seller to authorize, approve and adopt this Agreement and the
transactions contemplated hereby. Without limiting the generality of the
foregoing, (i) Seller agrees that its obligation to duly call, give notice of,
convene and hold a meeting of the holders of Seller Common Stock, as required by
this Section 5.05, shall not be affected by the withdrawal, amendment or
modification of the Seller Board Recommendation and (ii) Seller agrees that its
obligations pursuant to this Section 5.05 shall not be affected by the

                                      -39-
<PAGE>

commencement, public proposal, public disclosure or communication to Seller of
any Acquisition Proposal or Superior Proposal.

            (d) Subject to Parent's and Acquisition Sub's fulfillment of their
obligations with respect thereto, Seller agrees and covenants that the Proxy
Statement shall contain (and shall be amended in a timely manner so as to
contain) all information which is required to be included therein in accordance
with the Exchange Act and the rules and regulations thereunder and any other
applicable Law and shall conform in all material respects with the requirements
of the Exchange Act and any other applicable Law, and the Proxy Statement shall
not, at the time it is filed with the SEC or published, sent or given to
Seller's stockholders, contain any untrue statement of a material fact or omit
to state any material fact required to be stated therein or necessary in order
to make the statements therein, in light of the circumstances under which they
are made, not misleading; provided, however, that no covenant is hereby made by
Seller with respect to any information supplied by Parent in writing for
inclusion in, or with respect to Parent information derived from Parent's public
SEC filings which is included or incorporated by reference in the Proxy
Statement.

            (e) Parent and Acquisition Sub agrees and covenants that none of the
information supplied or to be supplied in writing by or on behalf of Parent or
Acquisition Sub for inclusion in the Proxy Statement shall, at the time the
Proxy Statement is mailed to the stockholders of Seller or at the time of the
Seller Stockholders' Meeting (or any adjournment or postponement thereof),
contain any untrue statement of a material fact or omit to state any material
fact required to be stated therein or necessary in order to make the statements
therein, in the light of the circumstances under which they are made, not
misleading.

            (f) If at any time after the date the Proxy Statement is mailed to
stockholders and prior to the Seller Stockholders' Meeting any information
relating to Seller, Parent or Acquisition Sub or any of their respective
Affiliates, officers or directors, is discovered by Seller, Parent or
Acquisition Sub which is required to be set forth in an amendment or supplement
to the Proxy Statement so that the Proxy Statement will not include any untrue
statement of a material fact or omit to state any material fact necessary to
make the statements therein, in light of the circumstances under which they were
made, not misleading, the party which discovers such information shall promptly
notify the other parties hereto and an appropriate amendment or supplement
describing such information shall be promptly filed with the SEC and to the
extent required by applicable Law, disseminated to the stockholders.

      SECTION 5.06. REGULATORY APPROVALS.

            (a) Each party shall use commercially reasonable efforts to file, as
soon as practicable after the date of this Agreement, all notices, reports and
other documents required to be filed by such party with any Governmental or
Regulatory Authority with respect to the transactions contemplated by this
Agreement, and to submit promptly any additional information requested by any
such Governmental or Regulatory Authority.

            (b) Each of Seller, Parent and Acquisition Sub shall:

                                      -40-
<PAGE>

                  (i) give the other party prompt notice of the commencement or
threat of commencement of any Proceeding by or before any Governmental or
Regulatory Authority with respect to the transactions contemplated by this
Agreement;

                  (ii) keep the other party informed as to the status of any
such Proceeding or threat; and

                  (iii) promptly inform the other party of any communication to
or from any Governmental or Regulatory Authority regarding the transactions
contemplated by this Agreement.

      SECTION 5.07. PREPARATION AND SHIPPING OF PURCHASED ASSETS.

Seller shall prepare in a commercially reasonable manner all of the Purchased
Assets for shipping, and will conduct such preparations in such a manner that
Parent and Acquisition Sub will have the opportunity to inspect and approve such
preparations at least five (5) Business Days prior to the Closing Date.
Immediately following the Closing Date, Seller will, upon prior notice by
Parent, deliver all or part (as indicated by Parent) of the Equipment and
Inventory "FOB Destination" to a site outside California, Michigan and Illinois
(as designated by Parent) using a common carrier and Parent will reimburse
Seller for the reasonable out of pocket costs for handling, packing and shipping
the Equipment and Inventory; and for all other Purchased Assets, Parent and
Acquisition Sub may remove, without delay, such Purchased Assets to its own
location, provided however that Parent will reimburse Seller for any reasonable
out of pocket costs for packing such Purchased Assets.

      SECTION 5.08. ADDITIONAL AGREEMENTS.

            (a) Subject to Section 5.08(b), Parent, Acquisition Sub and Seller
shall use commercially reasonable efforts to take, or cause to be taken, all
actions necessary to consummate and make effective the transactions contemplated
by this Agreement. Without limiting the generality of the foregoing, but subject
to Section 5.08(b), each party to this Agreement:

                  (i) shall make all filings with a Governmental or Regulatory
Authority and shall use commercially reasonable efforts to give all notices
required to be made and given by such party in connection with the transactions
contemplated by this Agreement;

                  (ii) shall use commercially reasonable efforts to obtain each
Consent (if any) required to be obtained (pursuant to any applicable Law or
Contract, or otherwise) by such party in connection with the transactions
contemplated by this Agreement; and

                  (iii) shall use commercially reasonable efforts to lift any
restraint, injunction or other legal bar to the transactions contemplated by
this Agreement. Each party shall promptly deliver to the other parties a copy of
each such filing made, each such notice given and each such Consent obtained by
such party during the Pre-Closing Period.

            (b) Notwithstanding anything to the contrary contained in this
Agreement, Parent and Acquisition Sub shall not have any obligation under this
Agreement:

                                      -41-
<PAGE>

                  (i) to dispose of or transfer any assets;

                  (ii) to discontinue offering any product or service;

                  (iii) to license or otherwise make available, to any Person,
any intellectual property;

                  (iv) to hold separate any assets or operations (either before
or after the Closing Date);

                  (v) to make any commitment (to any Governmental or Regulatory
Authority or otherwise) regarding its future operations; or

                  (vi) to contest any Proceeding relating to the transactions
contemplated by this Agreement if Parent or Acquisition Sub determines in good
faith that contesting such Proceeding might not be advisable.

      SECTION 5.09. PUBLIC ANNOUNCEMENTS.

Parent, Acquisition Sub and Seller shall consult with each other before issuing
any press release or making any public statement with respect to this Agreement
or the transactions contemplated hereby and, except as may be required by
applicable Law, shall not issue any such press release or make any such public
statement prior to such consultation.

      SECTION 5.10. PARENT AND ACQUISITION SUB.

Parent shall cause Acquisition Sub to pay the Consideration set forth in Section
2.04 and to perform its other obligations under this Agreement.

                                    ARTICLE 6
                              CONDITIONS TO CLOSING

      SECTION 6.01. CONDITIONS TO PARENT'S AND ACQUISITION SUB'S OBLIGATIONS.

The obligation of Parent and Acquisition Sub to consummate the transactions
contemplated by this Agreement is subject to the satisfaction, at or prior to
the Closing Date, of the following conditions:

            (a) no temporary restraining order, preliminary or permanent
injunction or other order preventing the consummation of the transactions
contemplated by this Agreement shall have been issued by any court of competent
jurisdiction and remain in effect, and there shall not be any Law enacted or
deemed applicable to this Agreement that makes consummation of transactions
contemplated by this Agreement illegal; provided that, subject to Section
5.08(b), in the case of a restraining order, injunction or other order, each of
the parties shall have used their commercially reasonable efforts to prevent the
entry of any such restraining order, injunction or other order and to appeal as
promptly as possible any restraining order, injunction or other order that may
be entered;

                                      -42-
<PAGE>
            (b) each of the representations and warranties of Seller contained
in this Agreement shall be true and correct in all material respects (determined
without regard to any knowledge or materiality qualification therein) as of the
date hereof and as of the Closing Date (other than to the extent any such
representation or warranty addresses a matter as of a particular date, in which
case such representation or warranty shall be true and correct in all material
respects as of such particular date, determined without regard to any knowledge
or materiality qualifications therein), except to the extent any such
representations and warranties are qualified by a Material Adverse Effect
qualification, in which case each such representation and warranty shall be true
and correct in all respects (determined without regard to knowledge
qualifications therein) as of the date hereof and as of the Closing Date (other
than to the extent any such representation or warranty addresses a matter as of
a particular date, in which case any such representation or warranty shall be
true and correct in all respects as of such particular date, determined without
regard to any knowledge qualifications therein); it being understood that this
condition will be deemed to be satisfied unless the failure of any such
representations and warranties to be true and correct, taken together in their
entirety, would, individually or in the aggregate, reasonably be expected to
have a Material Adverse Effect;

            (c) no action, event or condition has occurred since the date hereof
that constitutes or could reasonably be expected to result in a Material Adverse
Effect;

            (d) there shall not be pending any Proceeding in which a
Governmental or Regulatory Authority is a party or otherwise involved, and
neither Parent and Acquisition Sub nor the Seller shall have received a
communication from any Governmental or Regulatory Authority in which such
Governmental or Regulatory Authority indicates the intention of commencing any
Proceeding or taking any other action, (i) challenging or seeking to restrain or
prohibit the consummation of the transactions contemplated by this Agreement;
(ii) relating to the transactions contemplated by this Agreement and seeking to
obtain from Parent and Acquisition Sub, any damages or other relief that may be
material to Parent and Acquisition Sub; (iii) that could materially and
adversely affect the right of Parent and Acquisition Sub to own the Purchased
Assets; or (iv) seeking to compel Parent and Acquisition Sub to dispose of or
hold separate any material assets as a result of the transactions contemplated
by this Agreement;

            (e) there shall not be pending any Proceeding, other than a
Proceeding described in the foregoing paragraph, which, in the reasonable
judgment of Parent and Acquisition Sub, has a reasonable likelihood of success,
(i) challenging or seeking to restrain or prohibit the consummation of the
transactions contemplated by this Agreement; (ii) relating to the transactions
contemplated by this Agreement and seeking to obtain from Parent and Acquisition
Sub any damages or other relief that may be material to Parent or Acquisition
Sub or to impose on Parent or Acquisition Sub any Liability except the Assumed
Liabilities; or (iii) that would materially and adversely affect the right of
Parent or Acquisition Sub to own the Purchased Assets;

            (f) this Agreement shall not have been terminated in accordance with
its terms;

                                      -43-
<PAGE>

            (g) each of the covenants and obligations of Seller to be performed
or complied with at or before the Closing Date pursuant to Article 5 of this
Agreement shall have been duly performed or complied with in all material
respects at or before the Closing Date;

            (h) Seller shall have purchased a supplemental extended reporting
period for an unlimited period of time on Seller's current product liability
insurance policy for the full limits of Ten Million Dollars ($10,000,000), which
names Parent and Acquisition Sub as additional insureds but only for covered
injury or damage that occurs prior to the Closing Date (the "TAIL POLICY"). The
form of the endorsement effecting the Tail Policy is attached hereto as Exhibit
F and a true and complete copy of the endorsement effecting the Tail Policy
shall be provided to Parent and Acquisition Sub prior to Closing.

            (i) at least three (3) Business Days prior to the Closing Date,
Parent and Acquisition Sub shall have received a pay-off letter from Sanofi
which states (i) the amount outstanding as of the Closing Date on Seller's
arbitration obligation due to Sanofi, which must be an amount equal to or less
than Ten Million Dollars ($10,000,000), (ii) that following the receipt of such
amount outstanding all Liens on the assets of Seller in favor of Sanofi,
including the Sanofi Liens, shall be deemed released, and (iii) that Parent or
Acquisition Sub may make all filings necessary with any Governmental or
Regulatory Authority in order to terminate any financing statement or other
evidence of a lien filed with such Governmental or Regulatory Authority (the
"PAY-OFF LETTER");

            (j) Seller shall have paid all amounts due and payable on or prior
to the Closing Date under the UCal Agreement;

            (k) Seller shall have obtained the Required Non-Governmental
Consents;

            (l) Seller shall have caused all of the Permits listed on Schedule
3.09(a) that relate to the Purchased Assets to be transferred to Acquisition Sub
except where such transfer is prohibited by Law, by Governmental or Regulatory
Authority, or by the terms and conditions of the Permits from being transferred;

            (m) this Agreement and the transactions contemplated hereby shall
have been duly adopted by the Required Seller Stockholder Vote;

            (n) all Liens on the Purchased Assets have been fully released ;

            (o) Acquisition Sub shall have received from Seller a letter in the
form of Exhibit D addressed to the FDA on Seller's letterhead and signed by
Seller notifying the FDA that all rights in the Purchased PMA have been
transferred to Acquisition Sub;

            (p) Acquisition Sub shall have received from Seller a letter in the
form of Exhibit G addressed to the BSI on Seller's letterhead and signed by
Seller notifying the BSI that all rights in the Purchased CE Marking(s) have
been transferred to Acquisition Sub;

            (q) Seller shall have prepared all of the Purchased Assets for
shipping in accordance with Section 5.07 and, to the extent any such Purchased
Assets are located on

                                      -44-
<PAGE>

property not under the control of Seller, Seller shall have obtained all
consents necessary to allow the Purchased Assets to be transferred pursuant to
Section 5.07;

            (r) Seller shall have filed a Medical Device Report under 21 C.F.R.
Part 803 with respect to the complaint submitted to the FDA by a user of the
GlucoWatch Biographer on December 30, 2002 (assigned Report Number 435942).

            (s) Parent and Acquisition Sub shall have received from Seller a
certificate in a form acceptable to Parent executed by an officer of Seller
which states that as of the Closing Date, Seller is Solvent and does not expect
to become Insolvent as a result of the transactions contemplated herein;

            (t) Seller shall have completed complaint trending for all time
periods from the commencement of commercial distribution of the Products through
the end of the fourth quarter of 2004.

            (u) Parent and Acquisition Sub shall have received from Seller all
complaints or medical device reports that have been or should have been reported
under 21 C.F.R. Part 820 that have not already been disclosed on Schedule
3.05(c)(iii) and all complaints or medical device reports that have been or
should have been reported to foreign regulatory authorities, including European
Union member state regulatory authorities, or to BSI;

            (v) Parent and Acquisition Sub shall have received from Seller:

                  (i) a certificate executed by a duly authorized officer of
Seller certifying the satisfaction of the conditions set forth in Section
6.01(b), Section 6.01(c) and Section 6.01(g);

                  (ii) a bill of sale transferring to Acquisition Sub all of the
Purchased Assets in the form of Exhibit A hereto dated as of the Closing Date;

                  (iii) Assignments by country transferring to Acquisition Sub
all of the Purchased Intellectual Property in the forms attached as Exhibit C-1,
Exhibit C-2 and Exhibit C-3 hereto dated as of the Closing Date; and

                  (iv) an assignment and assumption agreement evidencing the
assignment to, and assumption by, Acquisition Sub of the Assumed Contracts in
the form of Exhibit B hereto dated as of the Closing Date; and

            (w) Seller and Acquisition Sub shall have executed a Transition
Agreement in the form set forth in Exhibit E hereto.

      SECTION 6.02. CONDITIONS TO SELLER'S OBLIGATIONS.

The obligations of Sellers to consummate the transactions contemplated by this
Agreement are subject to the satisfaction, at or prior to the Closing Date, of
the following conditions:

                                      -45-
<PAGE>

            (a) no temporary restraining order, preliminary or permanent
injunction or other order preventing the consummation of the transactions
contemplated by this Agreement shall have been issued by any court of competent
jurisdiction and remain in effect, and there shall not be any Law enacted or
deemed applicable to this Agreement that makes consummation of transactions
contemplated by this Agreement illegal; provided that, subject to Section
5.08(b), in the case of a restraining order, injunction or other order, each of
the parties shall have used their commercially reasonable efforts to prevent the
entry of any such restraining order, injunction or other order and to appeal as
promptly as possible any restraining order, injunction or other order that may
be entered;

            (b) each of the representations and warranties of Parent and
Acquisition Sub contained in this Agreement shall be true and correct in all
material respects (determined without regard to any knowledge or materiality
qualifications therein) as of the date hereof and as of the Closing Date (other
than to the extent any such representation or warranty addresses a matter as of
a particular date, in which case such representation or warranty shall be true
and correct as of such particular date, determined without regard to any
knowledge or materiality qualifications therein), it being understood that this
condition will be deemed to be satisfied unless the failure of any such
representations and warranties to be true and correct, taken together in their
entirety, would, individually or in the aggregate, reasonably be expected to
have a material adverse effect on the ability of Parent or Acquisition Sub to
consummate the transactions contemplated by this Agreement;

            (c) each of the covenants and obligations of Parent and Acquisition
Sub to be performed or complied with at or before the Closing Date pursuant to
the terms of this Agreement shall have been duly performed or complied with in
all material respects at or before the Closing Date; and

            (d) this Agreement and the transactions contemplated thereby shall
have been duly adopted by the Required Seller Stockholder Vote; and

            (e) Seller shall have received from Parent a certificate executed by
a duly authorized officer of Parent certifying the satisfaction of the
conditions set forth in Section 6.02(b) and Section 6.02(c);

            (f) Seller shall have received from Acquisition Sub a certificate
executed by a duly authorized officer of Acquisition Sub certifying the
satisfaction of the conditions set forth in Section 6.02(b) and Section 6.02(c);
and

            (g) Seller shall have received from Acquisition Sub state
sales and use tax resale exemption certificates and shall have received from
Parent manufacturer's use tax exemption certificates for the necessary states.

                                    ARTICLE 7
                                   TERMINATION

      SECTION 7.01. TERMINATION.

This Agreement may be terminated prior to the Closing Date for any reason
provided below:

                                      -46-
<PAGE>

            (a) by mutual written consent of Parent and Seller;

            (b) by either Parent or Seller if a court of competent jurisdiction
or other Governmental or Regulatory Authority shall have issued a final and
nonappealable order, decree or ruling, or shall have taken any other action,
having the effect of permanently restraining, enjoining or otherwise making
consummation of the transactions contemplated by this Agreement illegal;
provided, that in the case of a restraining order, injunction or other order,
each of the parties shall have used their commercially reasonable efforts to
prevent the entry of any such restraining order, injunction or other order and
to appeal as promptly as possible any restraining order, injunction or other
order that may be entered;

            (c) by either Parent or Seller if the transactions contemplated by
this Agreement are not consummated by the Termination Date; provided, however,
that: (i) a party shall not be permitted to terminate this Agreement pursuant to
this Section 7.01(c) if the failure to consummate the transactions contemplated
hereby is attributable to a failure on the part of such party to perform or
comply with any covenant in this Agreement required to be performed or complied
with by such party at or prior to the Closing Date; and (ii) Seller shall not be
permitted to terminate this Agreement pursuant to this Section 7.01(c) unless
Seller shall have made any payment required to be made to Parent pursuant to
Section 7.03(a) and shall have paid to Parent the fee, if any, required to be
paid to Parent pursuant to Section 7.03(c);

            (d) If a Triggering Event shall have occurred, by Parent at any time
within five (5) Business Days of Parent's or Acquisition Sub's receipt of notice
of the occurrence of such Triggering Event;

             (e) by Parent if any of the representations and warranties of
Seller set forth in this Agreement which are not qualified by "materiality" or
"Material Adverse Effect" shall not have been true and correct in all material
respects as of the date of this Agreement, or the representations and warranties
that are qualified by "materiality" or "Material Adverse Effect" shall not have
been true and correct in all respects as of the date of this Agreement, in
either case, such that Section 6.01(b) would not be satisfied (it being
understood that, for purposes of determining the accuracy of such
representations and warranties as of the date of this Agreement, any update of
or modification to the schedules hereto made or purported to have been made
after the date of this Agreement shall be disregarded);

            (f) by Seller if any of Parent's or Acquisition Sub's
representations and warranties contained in this Agreement shall fail to be true
and correct as of the date of this Agreement, except where such failure does not
have a material adverse effect on the ability of Parent or Acquisition Sub to
consummate the transactions contemplated by this Agreement;

            (g) by Seller if Seller has proposed to enter into or entered into
an agreement with respect to a Superior Proposal or has approved or recommended
a Superior Proposal in accordance with Section 5.04, provided that Seller has
complied with all of the provisions of Section 5.04, including the notice
provisions therein, and that simultaneously with terminating this Agreement
Seller makes all payments required to be made to Parent pursuant to Section
7.03;

                                      -47-
<PAGE>

            (h) by Seller or Parent if the Required Seller Stockholder Vote is
not received at any meeting, or any adjournment thereof, of Seller's
stockholders held for the purpose of approving this Agreement and the
transactions contemplated by this Agreement; and at which a vote is taken to
approve this Agreement and the transactions contemplated by this Agreement;

            (i) by Parent pursuant to Section 5.03 of this Agreement; or

            (j) by Parent if Seller has a Material Adverse Effect.

      SECTION 7.02. EFFECT OF TERMINATION.

In the event of the termination of this Agreement as provided in Section 7.01,
this Agreement shall be of no further force or effect; provided, however, that
(i) this Section 7.02, Section 7.03, Article 9 and Article 10 (and the
Confidentiality Agreement) shall survive the termination of this Agreement and
shall remain in full force and effect, and (ii) the termination of this
Agreement shall not relieve any party from any liability for any breach of any
representation or warranty, or any material breach of any covenant, obligation
or other provision contained in this Agreement; provided however, that, upon
receipt by Parent of the Termination Fee and any nonrefundable expense
reimbursement under Section 7.03(a) in accordance with the provisions hereof,
Parent and Acquisition Sub shall have no further rights hereunder, at law or in
equity, to damages or other relief and shall release and forever discharge
Seller, and each of its past, present and future representatives, Affiliates,
stockholders, directors, officers, employees, subsidiaries, successors and
assigns from any and all claims, demands, proceedings or other obligations,
known or unknown, both at law and in equity, which Parent and Acquisition Sub
may ever have against such Persons arising out of any matter, cause or event
occurring on or prior to the date of such receipt by Parent of the Termination
Fee and any nonrefundable expense reimbursement under Section 7.03(a).

      SECTION 7.03. EXPENSES; TERMINATION FEES.

            (a) Except as set forth in this Section 7.03 and Section 10.03, all
fees and expenses incurred in connection with this Agreement and the
transactions contemplated by this Agreement shall be paid by the party incurring
such expenses, whether or not the transactions contemplated by this Agreement
are consummated; provided, however, that if this Agreement is terminated by
Parent pursuant to Section 7.01(c), Section 7.01(d), Section 7.01(e), Section
7.01(h) or Section 7.01(j), or if this Agreement is terminated by Seller
pursuant to Section 7.01(c), Section 7.01(g) or Section 7.01(h), then (without
limiting any obligation of Seller to pay any fee payable pursuant to Section
7.03(c)), Seller shall make a nonrefundable cash payment to Parent, at the time
specified in Section 7.03(b), in an amount, up to a maximum of Two Hundred Fifty
Thousand Dollars ($250,000), equal to the aggregate amount of all reasonable out
of pocket fees and expenses (including all attorneys' fees, accountants' fees,
financial advisory fees and all filing fees) that have been paid or that may
become payable by or on behalf of Parent in connection with the due diligence
review of Seller by Parent and its respective Representatives, the preparation
and negotiation of this Agreement and otherwise in connection with the
transactions contemplated by this Agreement.

                                      -48-
<PAGE>

            (b) In the case of termination of this Agreement by Seller pursuant
to Section 7.01(c), Section 7.01(g) or Section 7.01(h), any nonrefundable
expense reimbursement payment required to be made pursuant to Section 7.03(a)
shall be made by Seller prior to the time of such termination if Seller has been
advised of such amount or two (2) Business Days following the time that Seller
has been advised of such amount; and in the case of termination of this
Agreement by Parent pursuant to Section 7.01(c), Section 7.01(d), Section
7.01(e), Section 7.01(h) or Section 7.01(j), any nonrefundable expense
reimbursement payment required to be made pursuant to Section 7.03(a) shall be
made by Seller within two (2) Business Days after such termination if Seller has
been advised of such amount or two (2) Business Days following the time that
Seller is advised of such amount.

            (c) If (i) this Agreement is terminated by Parent or Seller pursuant
to Section 7.01(h) and, prior to the time of the meeting of Seller's
stockholders held for the purpose of approving the transactions contemplated by
this Agreement, a bona fide Acquisition Proposal shall have been publicly
disclosed or announced and not withdrawn and within one (1) year from the date
of termination Seller consummates an Acquisition Proposal, (ii) this Agreement
is terminated by Parent or Seller pursuant to Section 7.01(c) or by Parent
pursuant to Section 7.01(e) or Section 7.01(j) and at or prior to the time of
termination of this Agreement, a bona fide Acquisition Proposal shall have been
publicly disclosed or announced and not withdrawn and within one (1) year from
the date of termination Seller consummates an Acquisition Proposal, (iii) this
Agreement is terminated by Parent pursuant to Section 7.01(d) or (iv) this
Agreement is terminated by Seller pursuant to Section 7.01(g), then Seller shall
pay to Parent, in cash at the time specified in the next sentence, a
nonrefundable fee in the amount equal to Five Hundred Thousand Dollars
($500,000), less any nonrefundable expense reimbursement payment required to be
made pursuant to Section 7.03(a) (the "TERMINATION FEE"); provided, however,
that for the purposes of this Section 7.03(c), the term "Acquisition Proposal"
shall have the meaning assigned to such term in Section 5.04(d) hereof, except
that the references to "significant portion" and "10%" in clauses (ii) and (iii)
of such definition, respectively, shall be deemed to be references to "more than
50%" and clause (i) of such definition shall be deemed amended and replaced in
its entirety by the following language: "(i) any merger, consolidation, share
exchange, business combination or similar transaction involving Seller pursuant
to which stockholders of Seller immediately prior to the consummation of such
transaction would cease to own directly or indirectly at least 50% of the voting
power of the outstanding securities of Seller (or of another Person that
directly or indirectly would own all or substantially all the assets of Seller)
immediately following such transaction in the same proportion as they owned
prior to the consummation of such transaction." In the case of termination of
this Agreement pursuant to clauses (i) or (ii) of this Section 7.03(c), the
Termination Fee shall be paid by Seller within two (2) Business Days after such
consummation of an Acquisition Proposal; in the case of termination of this
Agreement by Parent pursuant to Section 7.01(d), the Termination Fee shall be
paid by Seller within two (2) Business Days after such termination; and in the
case of termination of this Agreement by Seller pursuant to Section 7.01(g), the
Termination Fee shall be paid by Seller at or prior to the time of such
termination.

            (d) If Seller fails to pay when due any amount payable under this
Section 7.03, then (i) Seller shall reimburse Parent for all costs and expenses
(including fees and disbursements of counsel) incurred in connection with the
collection of such overdue amount and the enforcement by Parent of its rights
under this Section 7.03, and (ii) Seller shall pay to Parent

                                      -49-
<PAGE>

interest on such overdue amount (for the period commencing as of the date such
overdue amount was originally required to be paid and ending on the date such
overdue amount is actually paid to Parent in full) at a rate per annum equal to
the "prime rate" (as announced by Bank of America or any successor thereto) in
effect on the date such overdue amount was originally required to be paid.

                                   ARTICLE 8
                      POST-CLOSING COVENANTS OF THE PARTIES

      SECTION 8.01. PUBLIC ANNOUNCEMENTS.

After the Closing Date, Parent and Seller shall continue to abide by the
restrictions on public announcements contained in Section 5.09.

      SECTION 8.02. ACCESS TO FACILITIES.

After the Closing Date, Seller shall provide Parent and Acquisition Sub access
to its facilities and, to the extent any such Purchased Assets are located on
property not under the control of Seller, Seller shall cause access to Parent
and Acquisition Sub to the Purchased Assets.

      SECTION 8.03. SEC FILINGS.

After the Closing Date, Seller shall cooperate with Parent in the preparation of
any filing with the SEC which may be required by Parent related to this
Agreement and the transactions contemplated herein, including without
limitation, the filing of a current report on Form 8-K announcing the Closing.

      SECTION 8.04. FINANCIAL STATEMENTS.

To the extent required to be filed by Parent under SEC rules and regulations,
Seller shall deliver to Parent, at Seller's expense, on the later of (i) the
Closing Date and (ii) March 10, 2005, audited financial statements with respect
to Seller which are compliant with GAAP and all applicable securities Laws.
Seller will pay the cost of producing such financial statements (including
without limitation any audit fees related to such financial statements) to the
extent such costs would otherwise be required to comply with Seller's SEC
reporting obligations. Seller shall cooperate with Parent to provide Parent with
any additional information Parent may reasonably require in connection with
Parent's filing obligations under SEC rules and regulations.

      SECTION 8.05. FDA AND OTHER REGULATORY COMPLIANCE.

            (a) After the Closing Date, Seller, Parent and Acquisition Sub shall
cooperate in the preparation of any documents, filings or approvals, including
without limitation any supplements to the Purchased PMA required by the FDA to
allow Parent or Acquisition Sub to sell, manufacture, service or otherwise have
full use and enjoyment of the Purchased Assets and the Products, provided that
each party shall bear its own costs.

            (b) After the Closing Date, Seller, Parent and Acquisition Sub shall
cooperate in the preparation of any documents, filings or approvals, including
without limitation any amendments or other filings required by BSI and/or the
relevant foreign authorities, for the maintenance of the CE Marking of the
Products or other foreign regulatory approvals, to allow

                                      -50-
<PAGE>

Parent or Acquisition Sub to sell, manufacture, service or otherwise have full
use and enjoyment of the Purchased Assets and the Products, provided that each
party shall bear its own costs.

      SECTION 8.06. PRODUCT LIABILITY INSURANCE.

After the Closing Date, Seller shall not act or fail to act in any way to
cancel, terminate or otherwise prohibit or reduce in any way Parent's or
Acquisition Sub's ability to be an insured under the Tail Policy.

      SECTION 8.07. NO DISTRIBUTIONS TO STOCKHOLDERS.

Seller shall not make distributions of any kind to its stockholders until all
Liabilities of Seller (other than Assumed Liabilities and contingent Liabilities
that are not Reportable Contingent Liabilities) have been satisfied, or provided
for, in full.

      SECTION 8.08. THIRD-PARTY CORRESPONDENCE.

For a period of ninety (90) calendar days after the Closing Date (and thereafter
only in the event that Seller continues as a body corporate), Seller shall use
commercially reasonable efforts to forward to Parent and Acquisition Sub at the
address contained in Section 10.02 within five (5) Business Days following the
receipt of:

            (a) any mail, written correspondence or other written communications
related to the Purchased Assets it receives on or after the Closing Date; or

            (b) all complaints about the Products, whether oral or written it
receives on or after the Closing Date.

      SECTION 8.09. FURTHER ASSURANCES.

Parent, Acquisition Sub and Seller shall execute and deliver such documents,
certificates, agreements and other writings and to take such other actions as
may be necessary or desirable in order to consummate or implement expeditiously
the transactions contemplated by this Agreement.

      SECTION 8.10. PURCHASED INTELLECTUAL PROPERTY.

Seller shall execute, acknowledge and deliver to Acquisition Sub all necessary
additional assignment documents for the Purchased Intellectual Property. Seller
shall not be responsible for the payment of recordation or registration fees or
the fees of Acquisition Sub's attorneys in connection with making such
recordations or registrations.

      SECTION 8.11. COBRA.

After the Closing Date, Seller shall assume any and all obligations arising
under the continuation coverage requirements of Section 4980B of the Code and by
COBRA or other applicable Law with respect to the Business Employees and their
beneficiaries who experience a "Qualifying Event" (as defined in COBRA) on,
prior to or after the Closing Date.

                                      -51-
<PAGE>

      SECTION 8.12. PRODUCT AND PRODUCT MATERIALS.

After the Closing Date, Parent and Acquisition Sub, to the extent Products or
advertising, marketing or promotional materials received from Seller are
distributed or caused to be distributed or sold, shall either delete all
references to "Cygnus, Inc.," "Sankyo Pharma, Inc." and "Sankyo Pharma" (and the
Sankyo Pharma logo) on such Products and materials or shall provide written
notice with all such Products and materials that Cygnus, Inc. and Sankyo Pharma
Inc. are no longer affiliated with the Product.

      SECTION 8.13. NON-AFFILIATION.

After the Closing Date, Seller shall use commercially reasonable efforts to
inform its customers, suppliers, manufacturers, financial institutions, and
other Persons having a current or prospective business relationship with Seller
that Seller is not affiliated or associated with any Purchased Assets beyond the
Closing Date. or with Parent or Acquisition Sub.

      SECTION 8.14. USE OF "CYGNUS" AND THE SWAN LOGO.

After the Closing Date and subject to the terms and conditions of the Transition
Agreement set forth as Exhibit E hereto, Seller shall cease and use reasonable
efforts to cause its customers, suppliers, manufacturers, financial institutions
and other Persons having current business relationships with Seller in the
conduct of the Business, with the exception of parties to the Assumed Contracts,
to cease the use of "Cygnus" and its swan logo as defined in the Transition
Agreement in the advertising, marketing, manufacturing and sale of the Products
and in reference to the Business. Seller shall not represent that it is
affiliated or associated with any Purchased Assets or with Parent or
Acquisition Sub after the Closing Date.

      SECTION 8.15. ALLOCATION SCHEDULE.

The allocation of the Consideration among the Purchased Assets will be in
compliance with Section 1060 of the Code and regulations promulgated thereunder.
Parent shall prepare and submit to Seller a completed U.S. Internal Revenue
Service Form 8594 at least sixty (60) calendar days prior to the due date of
such Form. Parent and Seller and their respective Affiliates, if necessary,
shall report, act and file Tax Returns (including but not limited to Form 8594)
in all respects and for all purposes consistent with such allocation prepared by
Parent.

                                    ARTICLE 9
                                 INDEMNIFICATION

      SECTION 9.01. BY SELLER.

Seller shall indemnify, defend and hold harmless Parent and Acquisition Sub and
their respective past, present and future Affiliates, officers, directors,
agents and employees (collectively, the "PURCHASER INDEMNIFIED PARTIES" and,
individually, each a "PURCHASER INDEMNIFIED PARTY"), from and after the Closing
Date, from and against any and all Claims (including, without limitation, Claims
arising out of facts or circumstances that have occurred on or prior to the
Closing Date, even though such Claim may not be filed or come to light until
after the Closing

                                      -52-
<PAGE>

Date), Proceedings and/or Losses, which a Purchaser Indemnified Party may
sustain, suffer or incur, resulting from, related to, or arising out of:

            (a) any breach of any representation or warranty by Seller contained
in this Agreement, any of the Seller Collateral Documents, or any schedule to
this Agreement;

            (b) any breach of any covenant, agreement or undertaking by Seller
contained in this Agreement, any of the Seller Collateral Documents, or any
schedule to this Agreement;

            (c) any Liabilities of Seller other than the Assumed Liabilities and
other than tort Liabilities;

            (d) any non-compliance with applicable Law relating to bulk sales,
bulk transfers and the like or to fraudulent conveyances, fraudulent transfers,
preferential transfers and the like by Seller;

            (e) any Liabilities which may arise out of any of the items listed
on Schedule 3.04(b);

            (f) any tort Liability (including without limitation, any contingent
tort Liability) resulting from bodily injury or property damage caused by the
Products but only to the extent such bodily injury or property damage occurred
prior to the Closing Date, regardless of whether or not such Claims are caused
or alleged to be caused, in whole or in part by the negligence or strict
liability of Parent or Acquisition Sub; and

            (g) any Claim or Court Order arising out of any of the foregoing
even though such Claim or Court Order may not be filed, become final, or come to
light until after the Closing Date.

It is acknowledged and agreed that the Purchaser Indemnified Parties shall not
have the right to seek indemnity (whether equitable, statutory, contractual or
otherwise) against Seller for any tort Liability (including without limitation,
any contingent tort Liability) resulting from bodily injury or property damage
caused by the Products to the extent such bodily injury or property damage
occurs on or after the Closing Date, and the Purchaser Indemnified Parties
hereby release Seller from all such claims. Effective as of the Closing Date,
Purchaser Indemnified Parties waive, and agree to waive in the future, any and
all rights of recovery against Seller and its past, present and future
Affiliates.

      SECTION 9.02. BY PARENT AND ACQUISITION SUB.

Parent and Acquisition Sub shall jointly and severally indemnify, defend and
hold harmless Seller and its past, current and future Affiliates, officers,
directors, agents and employees (collectively, the "SELLER INDEMNIFIED PARTIES"
and, individually, a "SELLER INDEMNIFIED PARTY") from and after the Closing
Date, from and against any and all Claims, Proceedings and/or Losses, which a
Seller Indemnified Party may sustain, suffer or incur, resulting from, related
to, or arising out of:

                                      -53-
<PAGE>
              (a) any breach of any representation or warranty by Parent or
Acquisition Sub contained in this Agreement, any of the Purchaser Collateral
Documents, or any schedule to this Agreement;

              (b) any breach of any covenant, agreement or undertaking by Parent
or Acquisition Sub contained in this Agreement, any of the Purchaser Collateral
Documents, or any schedule to this Agreement;

            (c) any of the Assumed Liabilities;

            (d) any tort Liability (including without limitation, any contingent
tort Liability) related to or arising out of any of the Products sold on or
after the Closing Date, regardless of whether or not such Claims are caused or
alleged to be caused, in whole or in part by the negligence or strict liability
of Seller;

            (e) any Liabilities related to or arising out of the operation of
the Business on or after the Closing Date; and

            (f) any Claim or Court Order arising out of any of the foregoing
even though such Claim or Court Order may not be filed, become filed, or come to
light after the Closing Date.

      SECTION 9.03. LIMITATIONS ON INDEMNITY

            (a) Notwithstanding the foregoing, (i) no amounts shall be payable
by Seller for a Claim made under Section 9.01 or by Parent or Acquisition Sub
for a Claim made under Section 9.02 unless and until the aggregate amount
payable thereunder exceeds Fifty Thousand Dollars ($50,000) (the "Deductible"),
in which event all amounts in excess thereof shall be due; (ii) no Claim for
indemnification under Section 9.01(a) or Section 9.02(a) shall first be asserted
after the expiration of the applicable representation or warranty pursuant to
Section 9.05; and (iii) in no event shall the maximum aggregate liability of
Seller with respect to its obligations under Section 9.01 exceed Two Million
Dollars ($2,000,000).

            (b) The amount of the Indemnifying Party's liability under this
Agreement shall be net of any applicable insurance proceeds, with the exception
of sums paid by Seller's insurance (including without limitation under the Tail
Policy), actually received by the Indemnified Party in respect of the Loss for
which indemnity is sought; provided, however, that Parent and Acquisition Sub
are not under any obligation to submit any claim for insurance with respect of
the Loss for which indemnity is sought. Further, the $2,000,000 limit of
liability in section 9.03(a) shall be reduced by any sums actually paid by
Seller's insurance (including without limitation under the Tail Policy).
Further, to the extent that Seller's insurance (including without limitation
under the Tail Policy) actually pays Parent and Acquisition Sub an amount equal
to or in excess of $2,000,000, Seller shall have no further obligation to make
indemnification payments under this Agreement.

            (c) Notwithstanding anything contained in this Agreement to the
contrary, except to the extent arising from fraud, bad faith or intentional
misrepresentation, no party shall be liable to the other party for any punitive
damages arising out of this Agreement except to the

                                      -54-
<PAGE>

extent that such party has incurred these liabilities from a third-party not a
party to this Agreement.

      SECTION 9.04. NOTICE AND DEFENSE; COSTS OF DEFENSE.

            (a) Promptly after acquiring knowledge of any Proceeding, Claim or
Loss against which an Indemnified Party is or may be entitled to indemnification
hereunder, such Indemnified Party shall send a Claim Notice to the Indemnifying
Party, but any failure to so provide the Claim Notice to the Indemnifying Party
shall not relieve the Indemnifying Party from any liability that it may have to
the Indemnified Party under this Article 9 except to the extent that the
Indemnifying Party's ability to defend or mitigate such Claim, Proceeding or
Loss, is materially prejudiced by the failure to give the Claim Notice and only
to extent thereof. The Indemnifying Party shall be entitled to participate in
the defense of such action and to assume control of such defense; provided,
however, that:

                  (i) the Indemnified Party shall be entitled to participate in
the defense of such Claim, Proceeding or Loss, and to employ counsel at its own
expense to assist in the handling of such Claim, Proceeding or Loss;

                  (ii) the Indemnifying Party shall obtain the prior written
approval of the Indemnified Party (such approval shall not be unreasonably
withheld, conditioned or delayed) before entering into any settlement of such
Claim, Proceeding or Loss or ceasing to defend against such Claim, Proceeding or
Loss, if, pursuant to or as a result of such settlement or cessation, injunctive
or other equitable relief would be imposed against the Indemnified Party;

                  (iii) the Indemnifying Party shall not consent to the entry of
any judgment or enter into any settlement that does not include as an
unconditional term thereof the giving by the claimant or plaintiff to each
Indemnified Party of a release of each such Indemnified Party from liability in
respect of such Claim, Proceeding or Loss; and

                  (iv) the Indemnifying Party shall not be entitled to control
but shall be entitled to participate at its own expense in the defense of, and
the Indemnified Party shall be entitled to have sole control at its own expense
over, the defense or settlement of any Claim, Proceeding or Loss to the extent
the Claim, Proceeding or Loss seeks an order, injunction or other equitable
relief against the Indemnified Party which, if successful, could materially
interfere with the business, operations, assets, condition or prospects of the
Indemnified Party. In such case, the Indemnified Party shall obtain the prior
written approval of the Indemnifying Party (such approval shall not be
unreasonably withheld) before entering into any settlement of such Claim,
Proceeding or Loss or ceasing to defend against such Claim, Proceeding or Loss,
if, pursuant to or a result of such settlement or cessation, injunctive or other
equitable relief would be imposed against the Indemnified Party.

            (b) After written notice by the Indemnifying Party to the
Indemnified Party of its election to assume control of the defense of any such
Claim, Proceeding or Loss, the Indemnifying Party shall not be liable to such
Indemnified Party hereunder for any legal expenses subsequently incurred by such
Indemnified Party in connection with the defense thereof. If the Indemnifying
Party does not assume control of the defense of such Claim,

                                      -55-
<PAGE>

Proceeding or Loss as provided in this Section 9.04, the Indemnified Party shall
have the right to defend such Claim in such manner as it may deem appropriate at
the cost and expense of the Indemnifying Party, and the Indemnifying Party will
promptly reimburse the Indemnified Party therefor in accordance with this
Section 9.04. The reimbursement of fees, costs and expenses required by this
Section 9.04 shall be made by periodic payments during the course of the
investigation or defense, as and when bills are received or expenses incurred.

      SECTION 9.05. SURVIVAL OF REPRESENTATIONS AND WARRANTIES.

Each of the representations and warranties in this Agreement shall survive the
Closing Date and shall remain in full force and effect in accordance with its
terms until ninety (90) calendar days after the Closing Date, after which they
shall expire.

      SECTION 9.06. CHARACTERIZATION OF INDEMNITY PAYMENTS.

To the extent permitted by applicable Law, any payment made pursuant to this
Article 9 shall be treated, for Tax purposes, as an adjustment to the
Consideration.

      SECTION 9.07. EXCLUSIVE REMEDY.

Each of the parties hereto (on its own behalf and on behalf of its respective
Affiliates or other Persons that may seek indemnification hereunder) hereby
acknowledges and agrees that, after the Closing Date, any indemnification by
this Article 9 (as subject to the limitations contained herein) shall be the
sole and exclusive remedy of such party and its Affiliates or other Persons for
any breach of the representations, warranties, covenants or agreements of the
other parties set forth in this Agreement or in any of the documents
contemplated hereby or other agreement, document or instrument delivered in
connection with the Closing; and each of the parties hereto hereby waives any
other remedy under law or in equity; provided, however, the foregoing limitation
shall not apply in the case of fraud, bad faith or intentional
misrepresentation.

                                   ARTICLE 10
                                  MISCELLANEOUS

      SECTION 10.01. ENTIRE AGREEMENT; ASSIGNMENT.

This Agreement (including the exhibits and schedules hereto) constitutes the
entire agreement between the parties hereto with respect to the subject matter
hereof and supersedes all other prior agreements and understandings, both
written and oral, between the parties with respect to the subject matter hereof
and is not intended to confer any rights or remedies upon any Person other than
the parties hereto except that the Seller Indemnified Parties and the Purchaser
Indemnified Parties are intended beneficiaries of the provisions of Article 9.
The parties shall not assign this Agreement to any Person (by operation of law
or otherwise) without the Consent of all other parties hereto.

      SECTION 10.02. NOTICES.

All notices, requests, claims, demands and other communications hereunder shall
be in writing and shall be given (and shall be deemed to have been duly given
upon receipt) by delivery in

                                      -56-
<PAGE>

person, by facsimile or by registered or certified mail (postage prepaid, return
receipt requested) to each other party as follows:

if to Seller to:

                                       Cygnus, Inc.
                                       400 Penobscot Drive
                                       Redwood City, CA 94063
                                       Facsimile: (650) 599-3913
                                       Attention: President/CEO

if to Parent or Acquisition Sub:

                                       Animas Corporation
                                       Animas Technologies LLC
                                       200 Lawrence Drive
                                       West Chester, PA 19380
                                       Facsimile: (610) 644-8717
                                       Attention: President

with a copy  (which shall not constitute notice) to:

                                       Pepper Hamilton LLP
                                       Two Logan Square
                                       18th & Arch Streets
                                       Philadelphia, PA 19103
                                       Facsimile: (215) 981-4750
                                       Attention: Barry M. Abelson, Esq.

      SECTION 10.03. EXPENSES.

Except as expressly set forth in this Agreement, Parent, Acquisition Sub and
Seller shall each pay their own costs and expenses incurred in connection with
this Agreement and the transactions contemplated hereby. Seller shall pay all
sales, use and any other taxes payable in connection with the transfer of the
Purchased Assets as contemplated hereby; provided, however, that Parent is
responsible for all other Taxes directly relating to the Purchased Assets
(including but not limited to property, sales and use Taxes) that are incurred
after the Closing Date.

      SECTION 10.04. GOVERNING LAW.

This Agreement shall be governed by and construed in accordance with the laws of
the State of Delaware without regard to any choice of law provisions (of the
State of Delaware or any other state).

      SECTION 10.05. CONSENT TO JURISDICTION.

Parent, Acquisition Sub and Seller agree that any suit, action or Proceeding
seeking to enforce any provision of, or based on any matter arising out of or in
connection with, this Agreement or

                                      -57-
<PAGE>

the transactions contemplated hereby shall be brought in the United States
District Court for the District of Delaware or any Delaware state court sitting
in Wilmington, Delaware, so long as one of such courts shall have subject matter
jurisdiction over such suit, action or Proceeding, and that any cause of action
arising out of this Agreement shall be deemed to have arisen from a transaction
of business in the State of Delaware, and each of the parties hereby irrevocably
Consents to the jurisdiction of such courts (and of the appropriate appellate
courts therefrom) in any such suit, action or Proceeding and irrevocably waives,
to the fullest extent permitted by Law, any objection that it may now or
hereafter have to the laying of the venue of any such suit, action or Proceeding
in any such court or that any such suit, action or Proceeding which is brought
in any such court has been brought in an inconvenient forum. Process in any such
suit, action or Proceeding may be served on any party anywhere in the world,
whether within or without the jurisdiction of any such court. Without limiting
the foregoing, each party agrees that service of process on such party as
provided in Section 10.02 shall be deemed effective service of process on such
party.

      SECTION 10.06. BANKRUPTCY QUALIFICATION.

Each representation or warranty made in or pursuant to this Agreement regarding
the enforceability of any Contract shall be qualified to the extent that such
enforceability may be affected by bankruptcy, insolvency and other similar Laws
or equitable principles (but not those concerning fraudulent conveyance)
generally affecting creditors' rights and remedies.

      SECTION 10.07. HEADINGS.

The headings in this Agreement are included for convenience of reference only
and shall be ignored in the construction or interpretation hereof.

      SECTION 10.08. SCHEDULES.

The schedules referred to in this Agreement shall correspond to the sections
contained in this Agreement, and disclosures set forth in any schedule shall
qualify the corresponding section of this Agreement.

      SECTION 10.09. SEVERABILITY.

Any term or provision of this Agreement that is held by a court of competent
jurisdiction or other authority to be invalid, void or unenforceable in any
situation in any jurisdiction shall not affect the validity or enforceability of
the remaining terms and provisions hereof or the validity or enforceability of
the offending term or provision in any other situation or in any other
jurisdiction. If the final judgment of a court of competent jurisdiction or
other authority declares that any term or provision hereof is invalid, void or
unenforceable, the parties agree that the court making such determination shall
have the power to reduce the scope, duration, area or applicability of the term
or provision, to delete specific words or phrases, or to replace any invalid,
void or unenforceable term or provision with a term or provision that is valid
and enforceable and that comes closest to expressing the intention of the
invalid or unenforceable term or provision.

      SECTION 10.10. RELIANCE BY PARENT AND ACQUISITION SUB.

                                      -58-
<PAGE>

Notwithstanding the right of Parent and Acquisition Sub to investigate the
business, assets and financial condition of Seller, and notwithstanding any
knowledge obtained or obtainable by Parent and Acquisition Sub as a result of
such investigation, Parent and Acquisition Sub has the unqualified right to rely
upon, and have relied upon, each of the representations and warranties made by
Seller in this Agreement or pursuant hereto.

      SECTION 10.11. COUNTERPARTS; FACSIMILE SIGNATURES; EFFECTIVENESS.

This Agreement may be executed in any number of counterparts (including
facsimile signature) each of which shall be an original with the same effect as
if the signatures thereto and hereto were upon the same instrument. This
Agreement shall become effective when each party hereto shall have received a
counterpart hereof signed by the other parties hereto.

                            [SIGNATURE PAGE FOLLOWS]

                                      -59-
<PAGE>

            IN WITNESS WHEREOF, the parties hereto have caused this Asset
Purchase Agreement to be duly executed by their respective authorized
signatories as of the date first above written.

                                 SELLER:

                                 CYGNUS, INC.

                                     By: /s/ John C. Hodgman
                                        ----------------------------------------
                                     Name:  John C. Hodgman
                                     Title: Chairman, President & CEO

                                PARENT:

                                ANIMAS CORPORATION

                                By: /s/ Katherine D. Crothall
                                    -------------------------------------------
                                    Name: Katherine D. Crothall, PhD
                                    Title: President and Chief Executive Officer

                                ACQUISITION SUB:

                                ANIMAS TECHNOLOGIES LLC

                                By: /s/ Katherine D. Crothall
                                    -------------------------------------------
                                     Name: Katherine D. Crothall, PhD
                                     Title: President

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