Document:

<PAGE>
                                                                   Exhibit 10.1

                            HARVARD APPARATUS, INC.

                       1996 STOCK OPTION AND GRANT PLAN

1.       PURPOSE

         This Stock Option and Grant Plan (the "Plan") is intended as a
performance incentive for officers, employees, directors, consultants and other
key persons of Harvard Apparatus, Inc. (the "Company") or its Subsidiaries (as
hereinafter defined) to enable the persons to whom options are granted (the
"Optionees") or to whom shares of common stock are granted (the "Grantees") to
acquire or increase a proprietary interest in the success of the Company. The
Company intends that this purpose will be effected by the granting of "incentive
stock options" ("Incentive Options") as defined in Section 422 of the Internal
Revenue Code of 1986, as amended (the "Code"), nonqualified stock options
("Nonqualified Options") and outright grants of common stock under the Plan. The
term "Subsidiaries" includes any corporations in which stock possessing fifty
percent or more of the total combined voting power of all classes of stock is
owned directly or indirectly by the Company.

2.       OPTIONS TO BE GRANTED AND ADMINISTRATION

         (a) Options granted under the Plan may be either Incentive Options or
Nonqualified Options, and shall be designated as such at the time of grant. To
the extent that any option intended to be an Incentive Option shall fail to
qualify as an "incentive stock option" under the Code, such option shall be
deemed to be a Nonqualified Option.

         (b) The Plan shall be administered by the Compensation Committee of the
Board of Directors of the Company (the "Board of Directors") or such other
committee as may from time to time be chosen by the Board of Directors (the
"Option Committee").

<PAGE>

         (c) Subject to the terms and conditions of the Plan, the Option
Committee shall have the power:

                  (i) To determine from time to time the options or stock to be
         granted to eligible persons under the Plan, to prescribe the terms and
         provisions (which need not be identical) of options or stock granted
         under the Plan to such persons and to approve the grant of options or
         stock, as the case may be;

                  (ii) To construe and interpret the Plan and grants thereunder
         and to establish, amend, and revoke rules and regulations for
         administration of the Plan. In this connection, the Option Committee
         may correct any defect or supply any omission, or reconcile any
         inconsistency in the Plan, in any option agreement, or in any related
         agreements, in the manner and to the extent it shall deem necessary or
         expedient to make the Plan fully effective. All decisions and
         determinations by the Option Committee in the exercise of this power
         shall be final and binding upon the Company, the Optionees and the
         Grantees;

                  (iii) to condition the grant of any award (or, in the case of
         stock options, the exercise of any stock option) on the entering into
         of an agreement by the recipient thereof, which such agreement may
         contain such terms and conditions as the Option Committee shall
         determine, including, without limitation, the granting of rights of
         first refusal, drag-along rights and voting requirements with respect
         to any Stock underlying any such award; and

                                       2
<PAGE>

                  (iv) Generally, to exercise such powers and to perform such
         acts as are deemed necessary or expedient to promote the best interests
         of the Company with respect to the Plan.

3.       STOCK

         (a) The stock granted under the Plan, or subject to the options granted
under the Plan, shall be shares of the Company's authorized but unissued common
stock, par value $.01 per share (the "Common Stock"). The total number of shares
that may be issued under the Plan shall not exceed an aggregate of 113,620
shares of Common Stock (such number shall be subject to adjustment as provided
in Section 7 hereof).

         (b) Whenever any outstanding option under the Plan expires, is
cancelled or is otherwise terminated (other than by exercise), the shares of
Common Stock allocable to the unexercised portion of such option may again be
the subject of options under the Plan or grants of Common Stock.

4.       ELIGIBILITY

         (a) Incentive Options may be granted only to officers or other
employees of the Company or its Subsidiaries, including members of the Board of
Directors who are also employees of the Company or its Subsidiaries.
Nonqualified Options may be granted to officers or other employees of the
Company or its Subsidiaries, members of the Board of Directors and consultants
and other key persons who provide services to the Company or its Subsidiaries
(regardless of whether they are also employees). Grants of Common Stock may be
made to any officer, director, employee, consultant or other key person of the
Company.

                                       3
<PAGE>

         (b) No person shall be eligible to receive any Incentive Option under
the Plan if, at the date of grant, such person beneficially owns stock
representing in excess of 10% of the voting power of all outstanding capital
stock of the Company (a "Ten Percent Stockholder") unless notwithstanding
anything in this Plan to the contrary (i) the purchase price for the Common
Stock subject to such option is at least 110% of the fair market value of such
stock at the time of the grant and (ii) the option by its terms is not
exercisable more than five (5) years from the date of grant thereof.

         (c) Notwithstanding any other provision of the Plan, to the extent that
the aggregate fair market value of the stock with respect to which Incentive
Options are exercisable for the first time by any individual during any calendar
year (under all plans of the Company and its parent and Subsidiaries) exceeds
$100,000, the options attributable to the excess over $100,000 shall be treated
as Nonqualified Options under the Plan. Such annual limitation shall be applied
by taking Incentive Options into account in the order in which they were
granted.

5.       TERMS OF THE OPTION AGREEMENTS

         Subject to the terms and conditions of the Plan, each option agreement
shall contain such provisions as the Option Committee shall from time to time
deem appropriate. Option agreements need not be identical, but each option
agreement by appropriate language shall include the substance of all of the
following provisions:

         (a) EXPIRATION; TERMINATION OF EMPLOYMENT. Notwithstanding any other
provision of the Plan or of any option agreement, each option shall expire on
the date specified in the option agreement, which date in the case of any
Incentive Option shall not be later than the tenth (10th) anniversary of the
date on which the option was granted; provided, however, that

                                       4
<PAGE>

if such Incentive Option is held by a Ten Percent Stockholder, the expiration
date of such Incentive Option shall not be later than five (5) years from the
date of grant thereof. If an Optionee's employment or service as a director with
the Company and its Subsidiaries terminates for any reason, the Option Committee
may (in addition to any terms and provisions contained in an option grant) in
its sole and absolute discretion provide, at any time, that any outstanding
option granted to such Optionee under the Plan shall be exercisable for not more
than three (3) months following termination of employment, subject to the
expiration date of such option.

         (b) MINIMUM SHARES EXERCISABLE. The minimum number of shares with
respect to which an option may be exercised at any one time shall be one hundred
(100) shares, or such lesser number as is subject to exercise under the option
at the time, provided that no fractional shares may be issued.

         (c) EXERCISE. Each option shall be exercisable in such installments
(which need not be equal) and at such times as may be designated by the Option
Committee. To the extent not exercised, installments shall accumulate and be
exercisable, in whole or in part, at any time after becoming exercisable, but
not later than the date the option expires.

         (d) PURCHASE PRICE. The purchase price per share of Common Stock
subject to each option shall be determined by the Option Committee; provided,
however, that the purchase price per share of Common Stock subject to each
Incentive Option shall be not less than the fair market value of the Common
Stock on the date such Incentive Option is granted. For the purposes of the
Plan, the fair market value of the Common Stock shall be determined in good
faith by the Option Committee; provided, however, that (i) if the Common Stock
is admitted to

                                       5
<PAGE>

quotation on the National Association of Securities Dealers Automated Quotation
System ("NASDAQ") on the date the option is granted, the fair market value shall
not be less than the average of the highest bid and lowest asked prices of the
Common Stock on NASDAQ reported for such date, or (ii) if the Common Stock is
admitted to trading on a national securities exchange or the NASDAQ National
Market System on the date the option is granted, the fair market value shall not
be less than the closing price reported for the Common Stock on such exchange or
system for such date or, if no sales were reported for such date, for the last
date preceding such date for which a sale was reported.

         (e) RIGHTS OF OPTIONEES. No Optionee shall be deemed for any purpose to
be the owner of any shares of Common Stock subject to any option unless and
until (i) the option shall have been exercised pursuant to the terms thereof,
(ii) all requirements under applicable law and regulations shall have been
complied with to the satisfaction of the Company, (iii) the Company shall have
issued and delivered the shares to the Optionee, and (iv) the Optionee's name
shall have been entered as a stockholder of record on the books of the Company.
Thereupon, the Optionee shall have full voting, dividend and other ownership
rights with respect to such shares of Common Stock.

         (f) TRANSFER. No option granted hereunder shall be transferable by the
Optionee other than by will or by the laws of descent and distribution, and such
option may be exercised during the Optionee's lifetime only by the Optionee, or
his or her guardian or legal representative.

                                       6
<PAGE>

5A.      TERMS OF STOCK GRANT

         Subject to the terms and conditions of this Plan, the Option Committee
may grant (or sell at a purchase price determined by such committee) shares of
Common Stock to eligible participants under this Plan. Such grants or issuances
may be on such terms as the Option Committee may determine, including
restrictions on transfer, rights of first refusal and repurchase provisions
based upon continuing employment and/or the achievement of performance goals or
other conditions. In no event may Common Stock issued or granted under this Plan
(other than as a result of the exercise of Options issued under this Plan) be
transferred or sold within six months of the date of issuance thereof.

6.       METHOD OF EXERCISE; PAYMENT OF PURCHASE PRICE

         (a) Any option granted under the Plan may be exercised by the Optionee
in whole or, subject to Section 5(b) hereof, in part by delivering to the
Company on any business day a written notice specifying the number of shares of
Common Stock the Optionee then desires to purchase (the "Notice"). As a
condition precedent to the exercise of any option (i) prior to the closing date
of the Company's first underwritten public offering of the Common Stock, on or
prior to the exercise date, the Optionee shall execute and deliver a Joinder
Agreement with substantially the terms attached hereto as EXHIBIT A, which may
be amended from time to time, and/or such other agreement containing such terms
and provisions as any option grant shall require as a condition to exercise, and
(ii) the Optionee shall pay or make arrangements for the payment of all taxes to
be withheld, in accordance with Section 9 of the Plan.

         (b) Payment for the shares of Common Stock purchased pursuant to the
exercise of an option shall be made either: (i) in cash, or by certified or bank
check or other payment

                                       7
<PAGE>

acceptable to the Company, equal to the option exercise price for the number of
shares specified in the Notice (the "Total Option Price"); (ii) if authorized by
the applicable option agreement and if permitted by law, by delivery of shares
of Common Stock that the optionee may freely transfer having a fair market
value, determined by reference to the provisions of Section 5(d) hereof, equal
to or less than the Total Option Price, plus cash in an amount equal to the
excess, if any, of the Total Option Price over the fair market value of such
shares of Common Stock; or (iii) by the Optionee delivering the Notice to the
Company together with irrevocable instructions to a broker to promptly deliver
the Total Option Price to the Company in cash or by other method of payment
acceptable to the Company; provided, however, that the Optionee and the broker
shall comply with such procedures and enter into such agreements of indemnity or
other agreements as the Company shall prescribe as a condition of payment under
this clause (iii).

         (c) The delivery of certificates representing shares of Common Stock to
be purchased pursuant to the exercise of an option will be contingent upon the
Company's receipt of the Total Option Price and of any written representations
from the Optionee required by the Option Committee, and the fulfillment of any
other requirements contained in the option agreement or applicable provisions of
law.

7.       ADJUSTMENT UPON CHANGES IN CAPITALIZATION

         (a) If the shares of the Company's Common Stock as a whole are
increased, decreased, changed into or exchanged for a different number or kind
of shares or securities of the Company, whether through merger, consolidation,
reorganization, recapitalization, reclassification, stock dividend, stock split,
combination of shares, exchange of shares, change

                                       8
<PAGE>

in corporate structure or the like, an appropriate and proportionate adjustment
shall be made in the number and kind of shares subject to the Plan, and in the
number, kind, and per share exercise price of shares subject to unexercised
options or portions thereof granted prior to any such change. In the event of
any such adjustment in an outstanding option, the Optionee thereafter shall have
the right to purchase the number of shares under such option at the per share
price, as so adjusted, which the Optionee could purchase at the total purchase
price applicable to the option immediately prior to such adjustment.

         (b) Adjustments under this Section 7 shall be determined by the Option
Committee and such determinations shall be conclusive and binding on all
persons. The Option Committee shall have the discretion and power in any such
event to determine and to make effective provision for acceleration of the time
or times at which any option or portion thereof shall become exercisable. No
fractional shares of Common Stock shall be issued under the Plan on account of
any adjustment specified above.

8.       EFFECT OF CERTAIN TRANSACTIONS

         In the case of (i) the dissolution or liquidation of the Company, (ii)
a reorganization, merger, consolidation or other business combination in which
the Company is acquired by another entity (other than a holding company formed
by the Company) or in which the Company is not the surviving entity, or (iii)
the sale of all or substantially all of the assets of the Company to another
entity, the Plan and the options issued hereunder shall terminate upon the
effectiveness of any such transaction or event, unless provision is made in
connection with such transaction for the assumption of options theretofore
granted, or the substitution for such options of new options of the successor
entity or parent thereof, with appropriate adjustment as

                                       9
<PAGE>

to the number and kind of shares and the per share exercise price, as provided
in Section 7. In the event of such termination, all outstanding vested options
shall be exercisable for at least fifteen (15) days prior to the date of such
termination.

9.       TAX WITHHOLDING

         Each Optionee shall, no later than the exercise date of any option, pay
to the Company, or make arrangements satisfactory to the Option Committee
regarding payment of any Federal, state, or local taxes of any kind required by
law to be withheld with respect to such income. The Company and its Subsidiaries
shall, to the extent permitted by law, have the right to deduct any such taxes
from any payment of any kind otherwise due to the Optionee.

10.      CONDITION TO GRANTS OF COMMON STOCK

         As a condition precedent to the grant of Common Stock to any Grantee
under the Plan prior to the closing date of the Company's first underwritten
public offering of the Common Stock, the Grantee shall execute and deliver a
Joinder Agreement with substantially the terms attached hereto as EXHIBIT A,
which may be amended from time to time, and/or such other agreement containing
such terms and provisions as the Option Committee shall require as a condition
to the grant. The Option Committee may also impose such other terms and
conditions on the grant of any Common Stock under the Plan as it may determine.

11.      AMENDMENT OF THE PLAN

         The Board of Directors may discontinue the Plan or amend the Plan at
any time, and from time to time, subject to any required regulatory approval and
the limitation that, except as provided in Sections 7 and 8 hereof, no amendment
shall be effective unless approved by the stockholders of the Company in
accordance with applicable law and regulations at an annual or

                                       10
<PAGE>

special meeting held within twelve months before or after the date of adoption
of such amendment, where such amendment will:

         (a)      increase the number of shares of Common Stock as to which
options may be granted under the Plan;

         (b)      change in substance Section 4 hereof relating to eligibility
to participate in the Plan;

         (c)      change the minimum option exercise price; or

         (d)      otherwise materially increase the benefits accruing to
participants under the Plan.

         Except as provided in Sections 7 and 8 hereof, rights and obligations
under any option granted before any amendment of the Plan shall not be altered
or impaired by such amendment, except with the consent of the Optionee.

12.      NONEXCLUSIVITY OF THE PLAN

         Neither the adoption of the Plan by the Board of Directors nor the
submission of the Plan to the stockholders of the Company for approval shall be
construed as creating any limitations on the power of the Board of Directors to
adopt such other incentive arrangements as it may deem desirable, including,
without limitation, the granting of stock or stock options otherwise than under
the Plan, and such arrangements may be either applicable generally or only in
specific cases. Neither the Plan nor any option granted hereunder shall be
deemed to confer upon any employee any right to continued employment with the
Company or its Subsidiaries.

                                       11
<PAGE>

13.      GOVERNMENT AND OTHER REGULATIONS; GOVERNING LAW

         (a) The obligation of the Company to sell and deliver shares of Common
Stock with respect to options granted under the Plan shall be subject to all
applicable laws, rules and regulations, including all applicable federal and
state securities laws, and the obtaining of all such approvals by governmental
agencies as may be deemed necessary or appropriate by the Option Committee.

         (b) The Plan shall be governed by Massachusetts law, except to the
extent that such law is preempted by federal law.

14.      EFFECTIVE DATE OF PLAN; STOCKHOLDER APPROVAL

         The Plan shall become effective upon the date that it is approved by
the Board of Directors of the Company; provided, however, that the Plan shall be
subject to the approval of the Company's stockholders in accordance with
applicable laws and regulations at an annual or special meeting held within
twelve (12) months of such effective date. No options granted under the Plan
prior to such stockholder approval may be exercised until such approval has been
obtained. No options may be granted under the Plan after the tenth anniversary
of the effective date of the Plan.

                                      * * *

Approved by Board of Directors:   May 29, 1996

Approved by Stockholders:   May, 1996

                                       12<PAGE>

                                                                    Exhibit 10.8

                        FORM OF INDEMNIFICATION AGREEMENT

         This Agreement made and entered into this ____ day of ______ 2000,
("Agreement"), by and between Harvard Bioscience, Inc., a Delaware corporation
(the "Company," which term shall include, where appropriate, any Entity (as
hereinafter defined) controlled directly or indirectly by the Company) and
____________ ("Indemnitee"):

         WHEREAS, it is essential to the Company that it be able to retain and
attract as directors the most capable persons available;

         WHEREAS, increased corporate litigation has subjected directors to
litigation risks and expenses, and the limitations on the availability of
directors and officers liability insurance have made it increasingly difficult
for the Company to attract and retain such persons;

         WHEREAS, the Company's Certificate of Incorporation, as amended from
time to time, and By-laws, as amended from time to time, require it to indemnify
its directors to the fullest extent permitted by law and permit it to make other
indemnification arrangements and agreements;

         WHEREAS, the Company desires to provide Indemnitee with specific
contractual assurance of Indemnitee's rights to full indemnification against
litigation risks and expenses (regardless, among other things, of any amendment
to or revocation of any such Certificate of Incorporation or By-laws or any
change in the ownership of the Company or the composition of its Board of
Directors);

         WHEREAS, the Company intends that this Agreement provide Indemnitee
with greater protection than that which is provided by the Company's Certificate
of Incorporation or Bylaws; and

         WHEREAS, Indemnitee is relying upon the rights afforded under this
Agreement in continuing as a director of the Company:

         NOW, THEREFORE, in consideration of the promises and the covenants
contained herein, the Company and Indemnitee do hereby covenant and agree as
follows:

         1.       DEFINITIONS.

                  (a)      "Corporate Status" describes the status of a person
                  who is serving or has served (i) as a director of the Company,
                  (ii) in any capacity with respect to any employee benefit plan
                  of the Company, or (iii) as a director, partner, trustee,
                  officer, employee, or agent of any other Entity at the request
                  of the Company.

<PAGE>

                  For purposes of subsection (iii) of this Section 1(a), if
                  Indemnitee is serving or has served as a director, partner,
                  trustee, officer, employee or agent of a Subsidiary,
                  Indemnitee shall be deemed to be serving at the request of the
                  Company.

                  (b)      "Entity" shall mean any corporation, partnership,
                  limited liability company, joint venture, trust, foundation,
                  association, organization or other legal entity.

                  (c)      "Expenses" shall mean all fees, costs and expenses
                  incurred by Indemnitee in connection with any Proceeding (as
                  defined below), including, without limitation, attorneys"
                  fees, disbursements and retainers (including, without
                  limitation, any such fees, disbursements and retainers
                  incurred by Indemnitee pursuant to Sections 10 and 11(c) of
                  this Agreement), fees and disbursements of expert witnesses,
                  private investigators and professional advisors (including,
                  without limitation, accountants and investment bankers), court
                  costs, transcript costs, fees of experts, travel expenses,
                  duplicating, printing and binding costs, telephone and fax
                  transmission charges, postage, delivery services, secretarial
                  services, and other disbursements and expenses.

                  (d)      "Indemnifiable Expenses," "Indemnifiable Liabilities"
                  and "Indemnifiable Amounts" shall have the meanings ascribed
                  to those terms in Section 3(a) below.

                  (e)      "Liabilities" shall mean judgments, damages,
                  liabilities, losses, penalties, excise taxes, fines and
                  amounts paid in settlement.

                  (f)      "Proceeding" shall mean any threatened, pending or
                  completed claim, action, suit, arbitration, alternate dispute
                  resolution process, investigation, administrative hearing,
                  appeal, or any other proceeding, whether civil, criminal,
                  administrative, arbitrative or investigative, whether formal
                  or informal, including a proceeding initiated by Indemnitee
                  pursuant to Section 10 of this Agreement to enforce
                  Indemnitee's rights hereunder.

                  (g)      "Subsidiary" shall mean any corporation, partnership,
                  limited liability company, joint venture, trust or other
                  Entity of which the Company owns (either directly or through
                  or together with another Subsidiary of the Company) either (i)
                  a general partner, managing member or other similar interest
                  or (ii) (A) 50% or more of the voting power of the voting
                  capital equity interests of such corporation, partnership,
                  limited liability company, joint venture or other Entity, or
                  (B) 50% or more of the outstanding voting capital stock or
                  other voting equity interests of such corporation,
                  partnership, limited liability company, joint venture or other
                  Entity.

         2.       SERVICES OF INDEMNITEE.  In consideration of the Company's
covenants and

<PAGE>

commitments hereunder, Indemnitee agrees to serve or continue to serve as a
director of the Company. However, this Agreement shall not impose any obligation
on Indemnitee or the Company to continue Indemnitee's service to the Company
beyond any period otherwise required by law or by other agreements or
commitments of the parties, if any.

         3.       AGREEMENT TO INDEMNIFY. The Company agrees to indemnify
Indemnitee as follows:

                  (a)      Subject to the exceptions contained in Section 4(a)
                  below, if Indemnitee was or is a party or is threatened to be
                  made a party to any Proceeding (other than an action by or in
                  the right of the Company) by reason of Indemnitee's Corporate
                  Status, Indemnitee shall be indemnified by the Company against
                  all Expenses and Liabilities incurred or paid by Indemnitee in
                  connection with such Proceeding (referred to herein as
                  "Indemnifiable Expenses" and "Indemnifiable Liabilities,"
                  respectively, and collectively as "Indemnifiable Amounts").

                  (b)      Subject to the exceptions contained in Section 4(b)
                  below, if Indemnitee was or is a party or is threatened to be
                  made a party to any Proceeding by or in the right of the
                  Company to procure a judgment in its favor by reason of
                  Indemnitee's Corporate Status, Indemnitee shall be indemnified
                  by the Company against all Indemnifiable Expenses.

         4.       EXCEPTIONS TO INDEMNIFICATION. Indemnitee shall be entitled to
indemnification under Sections 3(a) and 3(b) above in all circumstances other
than the following:

                  (a)      If indemnification is requested under Section 3(a)
                  and it has been adjudicated finally by a court of competent
                  jurisdiction that, in connection with the subject of the
                  Proceeding out of which the claim for indemnification has
                  arisen, Indemnitee failed to act (i) in good faith and (ii) in
                  a manner Indemnitee reasonably believed to be in or not
                  opposed to the best interests of the Company, or, with respect
                  to any criminal action or proceeding, Indemnitee had
                  reasonable cause to believe that Indemnitee's conduct was
                  unlawful, Indemnitee shall not be entitled to payment of
                  Indemnifiable Amounts hereunder.

                  (b)      If indemnification is requested under Section 3(b)
                  and

                                    (i) it has been adjudicated finally by a
                                    court of competent jurisdiction that, in
                                    connection with the subject of the
                                    Proceeding out of which the claim for
                                    indemnification has arisen, Indemnitee
                                    failed to act (A) in good faith and (B) in a
                                    manner Indemnitee reasonably believed to be
                                    in or not opposed to the best interests of
                                    the Company, Indemnitee shall not be
                                    entitled to payment of Indemnifiable
                                    Expenses hereunder; or

                                    (ii) it has been adjudicated finally by a
                                    court of competent

<PAGE>

                                    jurisdiction that Indemnitee is liable to
                                    the Company with respect to any claim, issue
                                    or matter involved in the Proceeding out of
                                    which the claim for indemnification has
                                    arisen, including, without limitation, a
                                    claim that Indemnitee received an improper
                                    personal benefit, no Indemnifiable Expenses
                                    shall be paid with respect to such claim,
                                    issue or matter unless the Court of Chancery
                                    or another court in which such Proceeding
                                    was brought shall determine upon application
                                    that, despite the adjudication of liability,
                                    but in view of all the circumstances of the
                                    case, Indemnitee is fairly and reasonably
                                    entitled to indemnity for such Indemnifiable
                                    Expenses which such court shall deem proper.

         5.       PROCEDURE FOR PAYMENT OF INDEMNIFIABLE AMOUNTS. Indemnitee
shall submit to the Company a written request specifying the Indemnifiable
Amounts for which Indemnitee seeks payment under Section 3 of this Agreement and
the basis for the claim. The Company shall pay such Indemnifiable Amounts to
Indemnitee within sixty (60) calendar days of receipt of the request. At the
request of the Company, Indemnitee shall furnish such documentation and
information as are reasonably available to Indemnitee and necessary to establish
that Indemnitee is entitled to indemnification hereunder.

         6.       INDEMNIFICATION FOR EXPENSES OF A PARTY WHO IS WHOLLY OR
PARTLY SUCCESSFUL. Notwithstanding any other provision of this Agreement, and
without limiting any such provision, to the extent that Indemnitee is, by reason
of Indemnitee's Corporate Status, a party to and is successful, on the merits or
otherwise, in any Proceeding, Indemnitee shall be indemnified against all
Expenses reasonably incurred by Indemnitee or on Indemnitee's behalf in
connection therewith. If Indemnitee is not wholly successful in such Proceeding
but is successful, on the merits or otherwise, as to one or more but less than
all claims, issues or matters in such Proceeding, the Company shall indemnify
Indemnitee against all Expenses reasonably incurred by Indemnitee or on
Indemnitee's behalf in connection with each successfully resolved claim, issue
or matter. For purposes of this Agreement, the termination of any claim, issue
or matter in such a Proceeding by dismissal, with or without prejudice, shall be
deemed to be a successful result as to such claim, issue or matter.

         7.       EFFECT OF CERTAIN RESOLUTIONS. Neither the settlement or
termination of any Proceeding nor the failure of the Company to award
indemnification or to determine that indemnification is payable shall create an
adverse presumption that Indemnitee is not entitled to indemnification
hereunder. In addition, the termination of any proceeding by judgment, order,
settlement, conviction, or upon a plea of nolo contendere or its equivalent
shall not create a presumption that Indemnitee did not act in good faith and in
a manner which Indemnitee reasonably believed to be in or not opposed to the
best interests of the Company or, with respect to any criminal action or
proceeding, had reasonable cause to believe that Indemnitee's action was
unlawful.

         8.       AGREEMENT TO ADVANCE EXPENSES; UNDERTAKING. The Company shall
advance all Expenses incurred by or on behalf Indemnitee in connection with any
Proceeding, including

<PAGE>

a Proceeding by or in the right of the Company, in which Indemnitee is involved
by reason of such Indemnitee's Corporate Status within thirty (30) days after
the receipt by the Company of a written statement from Indemnitee requesting
such advance or advances from time to time, whether prior to or after final
disposition of such Proceeding. To the extent required by Delaware law,
Indemnitee hereby undertakes to repay the amount of Indemnifiable Expenses paid
to Indemnitee if it is finally determined by a court of competent jurisdiction
that Indemnitee is not entitled under this Agreement to indemnification with
respect to such Expenses. This undertaking is an unlimited general obligation of
Indemnitee.

         9.       PROCEDURE FOR ADVANCE PAYMENT OF EXPENSES. Indemnitee shall
submit to the Company a written request specifying the Indemnifiable Expenses
for which Indemnitee seeks an advancement under Section 8 of this Agreement,
together with documentation evidencing that Indemnitee has incurred such
Indemnifiable Expenses. Payment of Indemnifiable Expenses under Section 8 shall
be made no later than thirty (30) calendar days after the Company's receipt of
such request.

         10.      REMEDIES OF INDEMNITEE.

                  (a)      RIGHT TO PETITION COURT. In the event that Indemnitee
                  makes a request for payment of Indemnifiable Amounts under
                  Sections 3 and 5 above or a request for an advancement of
                  Indemnifiable Expenses under Sections 8 and 9 above and the
                  Company fails to make such payment or advancement in a timely
                  manner pursuant to the terms of this Agreement, Indemnitee may
                  petition the Court of Chancery to enforce the Company's
                  obligations under this Agreement.

                  (b)      BURDEN OF PROOF. In any judicial proceeding brought
                  under Section 10(a) above, the Company shall have the burden
                  of proving that Indemnitee is not entitled to payment of
                  Indemnifiable Amounts hereunder.

                  (c)      EXPENSES. If Indemnitee is successful in whole or in
                  part in connection with any action brought by Indemnitee under
                  Section 10(a) above, the Company agrees to reimburse
                  Indemnitee in full for any Expenses incurred by Indemnitee in
                  connection with investigating, preparing for, litigating,
                  defending or settling any such action, or in connection with
                  any claim or counterclaim brought by the Company in connection
                  therewith.

                  (d)      VALIDITY OF AGREEMENT. The Company shall be precluded
                  from asserting in any Proceeding, including, without
                  limitation, an action under Section 10(a) above, that the
                  provisions of this Agreement are not valid, binding and
                  enforceable or that there is insufficient consideration for
                  this Agreement and shall stipulate in court that the Company
                  is bound by all the provisions of this Agreement.

                  (e)      FAILURE TO ACT NOT A DEFENSE. The failure of the
                  Company (including its Board of Directors or any committee
                  thereof, independent legal counsel, or

<PAGE>

                  stockholders) to make a determination concerning the
                  permissibility of the payment of Indemnifiable Amounts or the
                  advancement of Indemnifiable Expenses under this Agreement
                  shall not be a defense in any action brought under Section
                  10(a) above, and shall not create a presumption that such
                  payment or advancement is not permissible.

         11.      DEFENSE OF THE UNDERLYING PROCEEDING.

                  (a)      NOTICE BY INDEMNITEE. Indemnitee agrees to notify the
                  Company promptly upon being served with any summons, citation,
                  subpoena, complaint, indictment, information, or other
                  document relating to any Proceeding which may result in the
                  payment of Indemnifiable Amounts or the advancement of
                  Indemnifiable Expenses hereunder; provided, however, that the
                  failure to give any such notice shall not disqualify
                  Indemnitee from the right to receive payments of Indemnifiable
                  Amounts or advancements of Indemnifiable Expenses unless the
                  Company's ability to defend in such Proceeding is materially
                  and adversely prejudiced thereby.

                  (b)      DEFENSE BY COMPANY. Subject to the provisions of the
                  last sentence of this Section 11(b) and of Section 11(c)
                  below, the Company shall have the right to defend Indemnitee
                  in any Proceeding which may give rise to the payment of
                  Indemnifiable Amounts hereunder; provided, however that the
                  Company shall notify Indemnitee of any such decision to defend
                  within ten (10) days of receipt of notice of any such
                  Proceeding under Section 11(a) above. The Company shall not,
                  without the prior written consent of Indemnitee, consent to
                  the entry of any judgment against Indemnitee or enter into any
                  settlement or compromise which (i) includes an admission of
                  fault of Indemnitee or (ii) does not include, as an
                  unconditional term thereof, the full release of Indemnitee
                  from all liability in respect of such Proceeding, which
                  release shall be in form and substance reasonably satisfactory
                  to Indemnitee. This Section 11(b) shall not apply to a
                  Proceeding brought by Indemnitee under Section 10(a) above or
                  pursuant to Section 19 below.

                  (c)      INDEMNITEE'S RIGHT TO COUNSEL. Notwithstanding the
                  provisions of Section 11(b) above, if in a Proceeding to which
                  Indemnitee is a party by reason of Indemnitee's Corporate
                  Status, Indemnitee reasonably concludes that it may have
                  separate defenses or counterclaims to assert with respect to
                  any issue which may not be consistent with the position of
                  other defendants in such Proceeding, or if the Company fails
                  to assume the defense of such proceeding in a timely manner,
                  Indemnitee shall be entitled to be represented by separate
                  legal counsel of Indemnitee's choice at the expense of the
                  Company. In addition, if the Company fails to comply with any
                  of its obligations under this Agreement or in the event that
                  the Company or any other person takes any action to declare
                  this Agreement void or unenforceable, or institutes any
                  action, suit or proceeding to deny or to recover from
                  Indemnitee the benefits intended to be

<PAGE>

                  provided to Indemnitee hereunder, Indemnitee shall have the
                  right to retain counsel of Indemnitee's choice, at the expense
                  of the Company, to represent Indemnitee in connection with any
                  such matter.

         12.      REPRESENTATIONS AND WARRANTIES OF THE COMPANY. The Company
hereby represents and warrants to Indemnitee as follows:

                  (a)      AUTHORITY. The Company has all necessary power and
                  authority to enter into, and be bound by the terms of, this
                  Agreement, and the execution, delivery and performance of the
                  undertakings contemplated by this Agreement have been duly
                  authorized by the Company.

                  (b)      ENFORCEABILITY. This Agreement, when executed and
                  delivered by the Company in accordance with the provisions
                  hereof, shall be a legal, valid and binding obligation of the
                  Company, enforceable against the Company in accordance with
                  its terms, except as such enforceability may be limited by
                  applicable bankruptcy, insolvency, moratorium, reorganization
                  or similar laws affecting the enforcement of creditors' rights
                  generally.

         13.      INSURANCE. The Company shall, from time to time, make the good
faith determination whether or not it is practicable for the Company to obtain
and maintain a policy or policies of insurance with a reputable insurance
company providing the Indemnitee with coverage for losses from wrongful acts,
and to ensure the Company's performance of its indemnification obligations under
this Agreement. Among other considerations, the Company will weigh the costs of
obtaining such insurance coverage against the protection afforded by such
coverage. In all policies of director and officer liability insurance,
Indemnitee shall be named as an insured in such a manner as to provide
Indemnitee the same rights and benefits as are accorded to the most favorably
insured of the Company's officers and directors. Notwithstanding the foregoing,
the Company shall have no obligation to obtain or maintain such insurance if the
Company determines in good faith that such insurance is not reasonably
available, if the premium costs for such insurance are disproportionate to the
amount of coverage provided, or if the coverage provided by such insurance is
limited by exclusions so as to provide an insufficient benefit. The Company
shall promptly notify Indemnitee of any good faith determination not to provide
such coverage.

         14.      CONTRACT RIGHTS NOT EXCLUSIVE. The rights to payment of
Indemnifiable Amounts and advancement of Indemnifiable Expenses provided by this
Agreement shall be in addition to, but not exclusive of, any other rights which
Indemnitee may have at any time under applicable law, the Company's By-laws or
Certificate of Incorporation, or any other agreement, vote of stockholders or
directors (or a committee of directors), or otherwise, both as to action in
Indemnitee's official capacity and as to action in any other capacity as a
result of Indemnitee's serving as a director of the Company.

         15.      SUCCESSORS. This Agreement shall be (a) binding upon all
successors and assigns of the Company (including any transferee of all or a
substantial portion of the business,

<PAGE>

stock and/or assets of the Company and any direct or indirect successor by
merger or consolidation or otherwise by operation of law) and (b) binding on and
shall inure to the benefit of the heirs, personal representatives, executors and
administrators of Indemnitee. This Agreement shall continue for the benefit of
Indemnitee and such heirs, personal representatives, executors and
administrators after Indemnitee has ceased to have Corporate Status.

         16.      SUBROGATION. In the event of any payment of Indemnifiable
Amounts under this Agreement, the Company shall be subrogated to the extent of
such payment to all of the rights of contribution or recovery of Indemnitee
against other persons, and Indemnitee shall take, at the request of the Company,
all reasonable action necessary to secure such rights, including the execution
of such documents as are necessary to enable the Company to bring suit to
enforce such rights.

         17.      CHANGE IN LAW. To the extent that a change in Delaware law
(whether by statute or judicial decision) shall permit broader indemnification
or advancement of expenses than is provided under the terms of the by-laws of
the Company and this Agreement, Indemnitee shall be entitled to such broader
indemnification and advancements, and this Agreement shall be deemed to be
amended to such extent.

         18.      SEVERABILITY. Whenever possible, each provision of this
Agreement shall be interpreted in such a manner as to be effective and valid
under applicable law, but if any provision of this Agreement, or any clause
thereof, shall be determined by a court of competent jurisdiction to be illegal,
invalid or unenforceable, in whole or in part, such provision or clause shall be
limited or modified in its application to the minimum extent necessary to make
such provision or clause valid, legal and enforceable, and the remaining
provisions and clauses of this Agreement shall remain fully enforceable and
binding on the parties.

         19.      INDEMNITEE AS PLAINTIFF. Except as provided in Section 10(c)
of this Agreement and in the next sentence, Indemnitee shall not be entitled to
payment of Indemnifiable Amounts or advancement of Indemnifiable Expenses with
respect to any Proceeding brought by Indemnitee against the Company, any Entity
which it controls, any director or officer thereof, or any third party, unless
the Board of Directors of the Company has consented to the initiation of such
Proceeding. This Section shall not apply to counterclaims or affirmative
defenses asserted by Indemnitee in an action brought against Indemnitee.

         20.      MODIFICATIONS AND WAIVER. Except as provided in Section 17
above with respect to changes in Delaware law which broaden the right of
Indemnitee to be indemnified by the Company, no supplement, modification or
amendment of this Agreement shall be binding unless executed in writing by each
of the parties hereto. No waiver of any of the provisions of this Agreement
shall be deemed or shall constitute a waiver of any other provisions of this
Agreement (whether or not similar), nor shall such waiver constitute a
continuing waiver.

<PAGE>

         21.      GENERAL NOTICES. All notices, requests, demands and other
communications hereunder shall be in writing and shall be deemed to have been
duly given (a) when delivered by hand, (b) when transmitted by facsimile and
receipt is acknowledged, or (c) if mailed by certified or registered mail with
postage prepaid, on the third business day after the date on which it is so
mailed:

                  (i)      If to Indemnitee, to:

                  (ii)     If to the Company, to:

                           Harvard Bioscience, Inc.
                           84 October Hill Road
                           Holliston, Massachusetts 01746-1371
                           Facsimile: (508) 429-8478
                           Attention: President

                           with a copy to:
                                 Goodwin, Procter and Hoar LLP
                                 One Exchange Place
                                 Boston, Massachusetts 02109-2881
                                 Facsimile: (617) 523-1231
                                 Attention: H. David Henken P.C.

or to such other address as may have been furnished in the same manner by any
party to the others.

         22.      GOVERNING LAW; CONSENT TO JURISDICTION; SERVICE OF PROCESS.
This Agreement shall be governed by and construed in accordance with the laws of
the State of Delaware without regard to its rules of conflict of laws. Each of
the Company and the Indemnitee hereby irrevocably and unconditionally consents
to submit to the exclusive jurisdiction of the Court of Chancery of the State of
Delaware and the courts of the United States of America located in the State of
Delaware (the "Delaware Courts") for any litigation arising out of or relating
to this Agreement and the transactions contemplated hereby (and agrees not to
commence any litigation relating thereto except in such courts), waives any
objection to the laying of venue of any such litigation in the Delaware Courts
and agrees not to plead or claim in any Delaware Court that such litigation
brought therein has been brought in an inconvenient forum. Each of the parties
hereto agrees, (a) to the extent such party is not otherwise subject to service
of process in the State of Delaware, to appoint and maintain an agent in the
State of Delaware as such party's agent for acceptance of legal process, and (b)
that service of process may also be made on such party by prepaid certified mail
with a proof of mailing receipt validated by the United States Postal Service
constituting evidence of valid service. Service made pursuant to (a) or (b)
above shall have the same legal force and effect as if served upon such party
personally within the State of Delaware. For purposes of implementing the
parties' agreement to appoint and maintain an agent for service of process in
the State of Delaware, each

<PAGE>

such party does hereby appoint [__________________________], as such agent
and each such party hereby agrees to complete all actions necessary for such
appointment.

                  [Remainder of page intentionally left blank.]

<PAGE>

         IN WITNESS WHEREOF, the parties hereto have executed this Agreement as
of the day and year first above written.

                                            HARVARD BIOSCIENCE, INC.

                                            By:
                                               ---------------------------------
                                                 Name:
                                                 Title:

                                            INDEMNITEE

                                            ------------------------------------

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00016-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00016-of-00352.parquet"}]]