Document:

EX-4.2

 Exhibit 4.2 
  

 
 MANNKIND CORPORATION 
THE CORPORATION WILL FURNISH
TO ANY STOCKHOLDER UPON REQUEST AND WITHOUT CHARGE A FULL STATEMENT OF THE POWERS, DESIGNATIONS, PREFERENCES AND RELATIVE, PARTICIPATING, OPTIONAL OR OTHER SPECIAL RIGHTS OF EACH AUTHORIZED CLASS OF STOCK OR SERIES THEREOF AND THE QUALIFICATIONS,
LIMITATIONS OR RESTRICTIONS OF SUCH PREFERENCES AND/OR RIGHTS, TO THE EXTENT THAT THE SAME HAVE BEEN FIXED, AND OF THE AUTHORITY OF THE BOARD OF DIRECTIONS TO DESIGNATE THE SAME WITH RESPECT TO ANY SHARES. SUCH REQUEST MAY BE MADE TO THE CORPORATION
OR TO ITS TRANSFER AGENT. 
The following abbreviations, when used in the inscription on the face of this certificate, shall be construed as though they were written
out in full according to applicable laws or regulations: 
TEN COM - as tenants in common 
TEN ENT - as tenants by the entireties 
JT TEN - as joint tenants with right of survivorship
and not as tenants in common 
UNIF GIFT MIN ACT - (Cust) under Uniform Gifts to Minors Act 
UNIF TRF MIN ACT - (Cust) (Minor) 
Custodian (Minor) (State) Custodian (until age) under
Uniform Transfers to Minors Act (State) 
Additional abbreviations may also be used though not in the above list. 
PLEASE INSERT SOCIAL SECURITY OR OTHER IDENTIFYING NUMBER OF ASSIGNEE 
For value received,
____________________________hereby sell, assign and transfer unto 
(PLEASE PRINT OR TYPEWRITE NAME AND ADDRESS, INCLUDING POSTAL ZIP CODE, OF ASSIGNEE) 
Shares 
of the stock represented by the within Certificate, and do hereby irrevocably
constitute and appoint 
Attorney 
to transfer the said stock on the books of
the within-named Corporation with full power of substitution in the premises. 
Dated: __________________________________________20 
Signature(s) Guaranteed: Medallion Guarantee Stamp 
THE SIGNATURE(S) SHOULD BE GUARANTEED BY AN
ELIGIBLE GUARANTOR INSTITUTION (Banks, Stockbrokers, Savings and Loan Associations and Credit Unions) WITH MEMBERSHIP IN AN APPROVED SIGNATURE GUARANTEE MEDALLION PROGRAM, PURSUANT TO S.E.C. RULE 17Ad-15.

Signature: 
Signature: 
Notice: The signature to this assignment must correspond with the name as written upon the face of the certificate, in every particular, without alteration or enlargement, or any
change whatever. 
The IRS requires that the named transfer agent (“we”) report the cost basis of certain shares or units acquired after January 1, 2011.
If your shares or units are covered by the legislation, and you requested to sell or transfer the shares or units using a specific cost basis calculation method, then we have processed as you requested. If you did not specify a cost basis
calculation method, then we have defaulted to the first in, first out (FIFO) method. Please consult your tax advisor if you need additional information about cost basis. 
If you do not keep in contact with the issuer or do not have any activity in your account for the time period specified by state law, your property may become subject to state
unclaimed property laws and transferred to the appropriate state. 
1234567 

 

 
 ZQ|CERT#|COY|CLS|RGSTRY|ACCT#|TRANSTYPE|RUN#|TRANS# 
COMMON STOCK 
PAR VALUE $0.01 
COMMON STOCK 
THIS CERTIFICATE IS TRANSFERABLE IN CANTON, MA, JERSEY CITY, NJ AND COLLEGE
STATION, TX 
MannKind Corporation 
Certificate 
Number 
ZQ00000000 
MANNKIND CORPORATION 
INCORPORATED UNDER THE LAWS OF THE STATE OF DELAWARE 
Shares 
* * 000000 * * * * * * * * * * * * * * * * * * 
* * * 000000 * * * * * * * * * * * * * * * * * 
* * * * 000000 * * * * * * * * * * * * * * * *

* * * * * 000000 * * * * * * * * * * * * * * * 
* * * * * * 000000 * * * * * *
* * * * * * * * 
THIS CERTIFIES THAT 
MR. SAMPLE & MRS. SAMPLE &

** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample

**** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David

Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander

David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. 
Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** 
Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample 
**** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David 
Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander 
David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. 
Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** 
Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Sample **** Mr. Sample 
MR. SAMPLE & MRS. SAMPLE 
is the owner of 
CUSIP 56400P 70 6 
SEE REVERSE FOR CERTAIN DEFINITIONS 
*** ZERO HUNDRED THOUSAND

**000000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares**** 
000000**Shares****000000**Shares***

*000000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares**** 
000000**Shares****000000**Shares****

000000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares**** 
000000**Shares****000000**Shares****0

00000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares**** 
000000**Shares****000000**Shares****00

0000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares**** 
000000**Shares****000000**Shares****000

000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares**** 
000000**Shares****000000**Shares****0000

00**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares**** 
000000**Shares****000000**Shares****00000

0**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares**** 
000000**Shares****000000**Shares****000000

**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares**** 
000000**Shares****000000**Shares****000000*

*Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares**** 
000000**Shares****000000**Shares****000000**

Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares****000000**Shares**** 
000000**Shares****000000**Shares****000000**S 
ZERO HUNDRED AND ZERO*** 
FULLY-PAID AND NON-ASSESSABLE SHARES OF COMMON STOCK, PAR VALUE $0.01 PER SHARE, OF 
MANNKIND CORPORATION 
Transferable on the books of the Corporation in person or by duly
authorized attorney upon surrender of this Certificate properly endorsed. This Certificate is not valid unless duly countersigned by the Transfer Agent and registered by the Registrar. 
In WITNESS WHEREOF, the said Corporation has caused this 
Certificate to be signed in facsimile
by its duly authorized officers and the facsimile corporate seal to be duly affixed hereto. 
CEO, CFO and Director 
MANNKIND CORPORATION CORPORATE 
SEAL 
DELAWARE 
DATED
DD-MMM-YYYY 
COUNTERSIGNED AND REGISTERED: COMPUTERSHARE INC. TRANSFER AGENT AND
REGISTRAR, 
Secretary 
SECURITY INSTRUCTIONS ON REVERSE 
By 
AUTHORIZED SIGNATURE 
CUSIP 
Holder ID Insurance Value Number of Shares DTC 
Certificate Numbers 
1234567890/1234567890 
1234567890/1234567890 
1234567890/1234567890 
1234567890/1234567890 
1234567890/1234567890 
1234567890/1234567890 
Total Transaction 
XXXXXX XX X 
XXXXXXXXXX 
1,000,000.00 
123456 
12345678 123456789012345 
Total 
1 
2 
3

4 
5 
6 
7

Num/No. Denom. 
1 
2 
3 
4

5 
6 
1 
2 
3

4 
5 
6 
MannKind Corporation 
PO BOX 43004, Providence, RI 02940-3004 
MR A SAMPLE 
DESIGNATION (IF ANY) ADD 1 
ADD 2 
ADD 3 
ADD 4 
1234567 
Printed by DATA BUSINESS FORMSEX-10.31

 Exhibit 10.31 

CONFIDENTIAL SETTLEMENT COMMUNICATION 

SUBJECT TO LCA SECTION 14.2, FRE 408, CPLR 4547 AND EQUIVALENT LAWS

 EXECUTION VERSION             

SETTLEMENT AGREEMENT 

THIS SETTLEMENT AGREEMENT (this “Agreement”) is made effective as of November 9, 2016 (the
“Effective Date”) by and among: 
 MannKind Corporation, a Delaware corporation (“MannKind”),
together with Technosphere International C.V., a Dutch limited partnership (“TICV”), and MannKind Netherlands B.V., a Dutch limited liability company (“BV,” and together with MannKind, TICV, and their
respective Affiliates, the “MK Entities”); and 
 sanofi-aventis U.S. LLC, a Delaware limited liability company
(“Sanofi” and together with its Affiliates, the “Sanofi Entities”). 
 For the purposes of this Agreement, each of the MK
Entities, on the one hand, and the Sanofi Entities, on the other hand, are referred to individually as a “Party” and collectively as the “Parties.” 

RECITALS 
 WHEREAS,
Sanofi-Aventis Deutschland GmbH (“Sanofi GmbH”), MannKind, BV and TICV entered into that certain License and Collaboration Agreement, dated August 11, 2014 (the “LCA”, and together with the Letter Agreement and
Supply Agreement (each as defined below), the “License and Supply Arrangement”), pursuant to which MannKind, TICV and BV granted Sanofi certain exclusive rights and licenses to Develop and Commercialize Product (each as defined in
the LCA); 
 WHEREAS, pursuant to that certain Assignment, dated September 19, 2014, by and between Sanofi GmbH and Sanofi,
Sanofi GmbH assigned the License and Supply Arrangement to Sanofi; 
 WHEREAS, pursuant to that certain letter, dated January 1,
2016 (and received by MannKind on January 4, 2016), from Sanofi to MannKind (the “Termination Letter”), Sanofi notified MannKind of its decision to terminate the License and Supply Arrangement; 

WHEREAS, pursuant to that certain Transition Agreement, dated April 4, 2016, by and between Sanofi and MannKind (the
“Transition Agreement”), the Parties transferred certain responsibilities for the Product to MannKind in accordance with Section 13.3(c) of the LCA; 

WHEREAS, MannKind has made certain assertions and allegations about Sanofi relating to the License and Supply Arrangement and
Sanofi’s performance thereunder in letters dated February 4, 2016, August 5, 2016, and October 23, 2016; 

WHEREAS, Sanofi has responded to and denied such assertions and allegations in letters dated February 12, 2016, September 20,
2016, October 13, 2016, and October 30, 2016; 
 WHEREAS, MannKind’s letter dated August 5, 2016 provided Sanofi
“Notice of Dispute” and formally invoked the dispute resolution procedure set forth in Section 14.1 of the LCA; 

 CONFIDENTIAL 

 

 WHEREAS, executives from Sanofi and MannKind met on September 29, 2016 to
“meet and attempt to resolve the dispute in face-to-face negotiations” as required by Section 14.1 of the LCA; 

WHEREAS, the MK Entities and the Sanofi Entities have determined that it is in their mutual benefit to resolve the matters discussed in
the letters referred to above (the Dispute”); 
 WHEREAS, in connection with the settlement of the Dispute, Sanofi’s
Affiliate, Aventisub LLC (“Aventisub”) has agreed to release MannKind from its obligation to pay Aventisub $71,562,138.31 under the Promissory Note and release certain security interests encumbering MannKind’s assets; and
Sanofi has agreed to accelerate certain payments owed by Sanofi to MannKind under the Supply Agreement; 
 WHEREAS, the payments by
Sanofi and release of financial obligations and encumbrances by MannKind are anticipated by MannKind to make available substantial current liquidity and facilitate MannKind’s future financing activities; and 

WHEREAS, the MK Entities agree that the benefits provided by the Sanofi Entities hereunder and in the Pay-Off Letter provide at least
reasonably equivalent value for the release of claims by the MK Entities hereunder. 
 NOW, THEREFORE, in accordance with the
foregoing Recitals, and in consideration of the mutual covenants contained herein, the Parties hereto agree as follows: 
  

	1.	Defined Terms. For purposes of this Agreement, the following capitalized terms are defined in this Section 1 and shall have the meaning specified herein. Capitalized terms which are used in
this Agreement but not defined in this Section 1 or elsewhere in this Agreement shall have the meanings given to them in the License and Supply Arrangement. 

 

	 	(a)	“Affiliate” of a Party means any Person that, directly or indirectly, through one or more intermediaries, now or hereafter controls, is controlled by, or is under common control with such Person as of
such date. As used herein, the term “control” (including the terms “controlling,” “controlled by” and “under common control with”) means the possession, directly or indirectly, of
the power to direct or cause the direction of the management and policies of a Person, whether through ownership of voting securities or other interests, by contract or otherwise 

 

	 	(b)	“Claims” means any and all of the following arising under the laws of the United States or any foreign jurisdiction: claims, counterclaims, cross-claims, demands, causes of action, Liabilities,
lawsuits, arbitrations, proceedings, third-party interventions, or any other form of claim, whether or not fixed, contingent or absolute, matured or unmatured, direct or indirect, liquidated or unliquidated, accrued or unaccrued, known or unknown,
whether or not required to be reflected in financial statements or disclosed in the notes thereto. 

  

	 	(c)	“Letter Agreement” means that certain Letter Agreement, dated August 11, 2014, by and among MannKind, TICV, BV and Sanofi GmbH. 

  

					
	 	  	SETTLEMENT AGREEMENT	  	PAGE 2  

 CONFIDENTIAL 

 

	 	(d)	“Liabilities” means debts, liabilities, losses, damages, attorneys’ fees, court costs, obligations, expenses, or any other form of cost or compensation, whether or not fixed, contingent or
absolute, matured or unmatured, direct or indirect, liquidated or unliquidated, accrued or unaccrued, known or unknown, whether or not required to be reflected in financial statements or disclosed in the notes thereto. 

 

	 	(e)	“Pay-Off Letter” means that certain Pay-Off Letter, dated as of even date herewith, by and between Aventisub and MannKind. 

 

	 	(f)	“Potential Claims” means any and all Claims arising or accruing prior to or as of the Effective Date against any Sanofi Entity or any MK Entity (or any Related Party thereof) of any nature, including
those arising from, relating to, based upon, or in connection with the Dispute, the License and Supply Arrangement, or the Transition Agreement. 

  

	 	(g)	“Promissory Note” means that certain Senior Secured Revolving Promissory Note, dated as of September 23, 2014, between MannKind and Aventisub. 

 

	 	(h)	“Related Parties” means, with respect to each of the MK Entities or the Sanofi Entities, such entity’s predecessors, successors, assigns, agents, representatives, directors, officers and employees,
solely, in each case, with respect to such Person’s representative capacity as such. 

  

	 	(i)	“Security Agreement” means that certain Guaranty and Security Agreement, dated as of September 23, 2014, by and among MannKind, MannKind LLC, and Aventisub. 

 

	 	(j)	“Supply Agreement” means that certain Supply Agreement, dated August 11, 2014, by and between MannKind and Sanofi, as assignee of Sanofi GmbH. 

 

	2.	Promissory Note and Security Agreement. In consideration of the execution of this Agreement and the mutual release of obligations contained herein, Aventisub and MannKind are terminating the Promissory
Note and the Security Agreement pursuant to the Pay-Off Letter attached hereto as Exhibit A. 

  

	3.	Insulin Payments and Put Options. 

  

	 	(a)	Purchase of Insulin. By no later than December 3, 2016, Sanofi shall purchase $10,184,504.07 worth of Amphastar Insulin from MannKind, and MannKind shall sell and provide Sanofi with such amount of Insulin,
in accordance with the terms of the Supply Agreement and on terms consistent with Sanofi’s purchases prior to the Effective Date of Amphastar Insulin pursuant to the Insulin Put Option. 

 

	 	(b)	Satisfaction and Termination of Insulin Put Option. Sanofi and the MK Entities hereby confirm and agree to terminate the Insulin Put Option as of the Effective Date, and do hereby terminate the Insulin Put Option
subject to Sanofi’s final purchase and MannKind’s final sale referred to in Section 3(a) above. Within sixty (60) days after the Effective Date, Sanofi shall pay MannKind $30,553,512.21 as acceleration, and in replacement, of all
other payments Sanofi would otherwise have been required to make in the future pursuant to the Insulin Put Option. Sanofi releases MannKind from its obligation to sell, and MannKind releases Sanofi from any obligation to purchase, any additional
Insulin. 

  

					
	 	  	SETTLEMENT AGREEMENT	  	PAGE 3  

 CONFIDENTIAL 

 

	4.	Forgiveness of RSM Audit Money. Sanofi (on behalf of itself and its Affiliates) hereby releases the MK Entities from any obligation to pay Sanofi (or any of its Affiliates) the $461,649.00 in uncharged
costs identified in that certain September 28, 2016 audit performed by RSM US LLP. 

  

	5.	Mutual Releases and Covenants Not to Sue or Assist. 

  

	 	(a)	MannKind Release and Covenant Not to Sue. The MK Entities, on behalf of themselves, and all of their Related Parties, hereby fully and forever, irrevocably and unconditionally: (i) release, acquit and
forever discharge all their Potential Claims against any Sanofi Entity or any of its Related Parties; and (ii) covenant and agree never to bring, assert, pursue, maintain, or join in any such Potential Claim.

 

	 	(b)	MannKind Covenant Not to Assist. The MK Entities, on behalf of themselves and all of their Related Parties, hereby fully and forever, irrevocably and unconditionally covenant and agree never to directly or
indirectly finance, fund, encourage, solicit, assist, or otherwise support any Potential Claim brought against any Sanofi Entity and any of its Related Parties by any other Person (including any Related Party of the MK Entities, or any third
Person). 

  

	 	(c)	Sanofi Release and Covenant Not to Sue. The Sanofi Entities, on behalf of themselves and all of their Related Parties, hereby fully and forever, irrevocably and unconditionally: (i) release, acquit and
forever discharge all of their Potential Claims against each MK Entity and each of its Related Parties; and (ii) covenant and agree never to bring, assert, pursue, maintain, or join in any such Potential Claim.

 

	 	(d)	Sanofi Covenant Not to Assist. The Sanofi Entities, on behalf of themselves and all of their Related Parties, hereby fully and forever, irrevocably and unconditionally covenant and agree never to directly or
indirectly finance, fund, encourage, solicit, assist, or otherwise support any Potential Claim brought against any MK Entity and any of its Related Parties by any other Person (including any Related Party of the Sanofi Entities, or any third
Person). 

  

	 	(e)	Waiver of Statutory Provisions. The Parties (on behalf of themselves, their Affiliates, and their Related Parties) expressly waive any right or benefit that may be available under Section 1542 of the
California Civil Code or any similar laws of any other jurisdiction. Section 1542 of the California Civil Code provides: 

  

	 	  	“A general release does not extend to claims which the creditor does not know or suspect to exist in his favor at the time of executing the release, which if known by him must have materially affected his
settlement with the debtor.” 

  

	 	(f)	No Release of Certain Transition Agreement Obligations. The releases and covenants granted by the MK Entities in this Section 5 will not release Sanofi’s remaining obligations under the Transition
Agreement specifically listed on Exhibit D of this Agreement, to be completed by the dates specified therein. 

  

					
	 	  	SETTLEMENT AGREEMENT	  	PAGE 4  

 CONFIDENTIAL 

 

	6.	No Admission of Liability. It is understood and agreed by the Parties that the execution of this Agreement, the mutual releases contained herein, and the performance by the Parties of their obligations
contained in this Agreement (including the payments made, and releases of indebtedness granted, by the Sanofi Entities) do not constitute an admission of any wrongdoing or liability whatsoever. This Agreement is a compromise in settlement of
disputed claims, and is not to be construed as an admission for any purpose other than as necessary to enforce the terms of this Agreement. Neither this Agreement, nor the statements contained herein, nor any act foregone or performed pursuant to or
in furtherance of this Agreement, is or may be deemed to be or may be used as an admission of, or evidence of, the validity of any right, claim or defense, or in any way referred to for any reason as against any of the Parties hereto in any
proceeding in any court or tribunal; provided, however, that once signed, the Parties may refer to this Agreement as evidence of, and to effectuate, the terms and conditions of this Agreement and the protections granted hereunder, and to enforce or
otherwise effectuate the terms of this Agreement. 

  

	7.	Confidentiality. The Parties hereby acknowledge and agree that the provisions of the LCA and Transition Agreement with respect to obligations regarding confidentiality and Confidential Information shall
remain in effect. 

  

	8.	Press Releases. As soon as practicable following the execution of this Agreement, MannKind may issue a press release announcing the existence of this Agreement and the transactions contemplated herein, but
such press release must be in the form attached to this Agreement as Exhibit B. Except as required by Applicable Laws, including disclosure requirements of the SEC, the NASDAQ stock exchange or any other stock exchange on which securities
issued by a Party or its Affiliates are traded, neither Party shall make any published announcement concerning this Agreement or the transactions contemplated herein without the prior written consent of the other, which shall not be unreasonably
withheld or delayed; provided, that it shall not be unreasonable for a Party to withhold consent with respect to any published announcement containing any of such Party’s Confidential Information. In the event of a required published
announcement, to the extent practicable under the circumstances, the Party making such announcement shall provide the other Party with a copy of the proposed text of such announcement sufficiently in advance of the scheduled release to afford such
other Party a reasonable opportunity to review and comment upon the proposed text. In the event MannKind receives any third party inquiries regarding the License and Supply Arrangement, the Transition Agreement, the Promissory Note, the Security
Agreement, this Agreement, or its relationship with the Sanofi Entities, MannKind shall only reply to such inquiries using a form materially similar as attached to this Agreement as Exhibit C or in a form approved by written consent of Sanofi
(such consent not to be unreasonably withheld or delayed). 

  

	9.	Bankruptcy Event. The Parties hereby agree that in the event MannKind becomes a debtor under the Bankruptcy Laws, and this Agreement is rejected or avoided in accordance with Bankruptcy Laws with the
result that Sanofi loses the benefits of sections 5(a) and 5(b) hereunder, then the parties shall be returned to their pre-settlement positions and Sanofi shall be entitled to damages resulting from MannKind’s breach of the Agreement.

  

					
	 	  	SETTLEMENT AGREEMENT	  	PAGE 5  

 CONFIDENTIAL 

 

	10.	Advice of Counsel. The Parties acknowledge that they have consulted with sophisticated attorney(s) of their own choosing regarding the rights, obligations, and other terms of this Agreement, that they have
entered into this Agreement knowingly, freely and voluntarily without coercion or undue influence, and that they have negotiated such terms at arm’s length and that they intend to be bound hereby. Each Party has undertaken such independent
investigation and evaluation as it deems appropriate and is entering this Agreement in reliance on the Party’s own investigation and advice, and not in reliance on any advice, disclosure, representation, or information provided by or expected
from any other Party or Party’s lawyers, except as expressly stated in this Agreement. Each Party assumes the risk that the facts or law may be other than it believes, and as such each Party agrees that no misunderstanding or misinformation of
fact or law shall be a ground for rescission hereof. 

  

	11.	Representations, Warranties and Covenants. 

  

	 	(a)	MK Entities. As of the Effective Date, the MK Entities signing this Agreement represent, warrant and covenant to the Sanofi Entities that: 

 

	 	(i)	they have all requisite legal right, power and authority to execute, deliver and perform this Agreement and grant the releases, covenants and other rights granted by the applicable parties in this Agreement, without
restriction or requirement of consent of any other Person; 

  

	 	(ii)	no MK Entity nor any of its respective Related Parties have assigned any Potential Claims to any third party; 

  

	 	(iii)	no MK Entity has granted, and no MK Entity shall grant, any rights to any Person that would conflict with, or prevent, the grant of the releases, covenants, and other rights granted hereunder; 

 

	 	(iv)	there are no liens, conveyances, mortgages, assignments, encumbrances, or other contracts that would prevent or impair their full and complete performance of the terms and conditions of this Agreement;

  

	 	(v)	the MK Entities are not aware of any third Person who has asserted or intends to assert a Potential Claim; 

  

	 	(vi)	they have the authority to settle and compromise all of the MK Entities’, and their Related Parties’, Potential Claims without the necessity of obtaining the consent of any other Person; 

 

	 	(vii)	the transactions contemplated by this Agreement and the Pay-Off Letter constitute the exchange of reasonable equivalent value for the benefits provided by each Party to the other Party; 

 

	 	(viii)	the MK Entities are generally able to pay their debts and satisfy their obligations as they come due; and 

  

					
	 	  	SETTLEMENT AGREEMENT	  	PAGE 6  

 CONFIDENTIAL 

 

	 	(ix)	the MK Entities have not been, and as of the Effective Date are not presently engaged in, discussions with any creditors relating to any filings by MannKind under any Bankruptcy Laws or similar proceedings.

  

	 	(b)	Sanofi. As of the Effective Date, Sanofi represents, warrants and covenants to the MK Entities that: 

  

	 	(i)	the Sanofi has all requisite legal right, power and authority to execute, deliver and perform this Agreement and grant the releases, covenants and other rights granted by the applicable parties in this Agreement,
without restriction or requirement of consent of any other Person; 

  

	 	(ii)	no Sanofi Entity nor any of its respective Related Parties have assigned any Potential Claims to any third party; 

  

	 	(iii)	no Sanofi Entity has granted, and no Sanofi entity shall grant, any rights to any Person that would conflict with, or prevent, the grant of the releases, covenants, and other rights granted hereunder; 

 

	 	(iv)	there are no liens, conveyances, mortgages, assignments, encumbrances, or other contracts that would prevent or impair its full and complete performance of the terms and conditions of this Agreement; 

 

	 	(v)	the Sanofi Entities are not aware of any third Person who has asserted or intends to assert a Potential Claim; 

  

	 	(vi)	it has the authority to settle and compromise all of the Sanofi Entities’, and the Sanofi Entities’ Related Parties’, Potential Claims without the necessity of obtaining the consent of any other Person;
and 

  

	 	(vii)	the transactions contemplated by this Agreement and the Pay-Off Letter constitute the exchange of reasonable equivalent value for the benefits provided by each Party to the other Party. 

 

	12.	Indemnification. Except as provided in this Agreement, the Parties agree that the indemnification obligations under the License and Supply Arrangement and Transition Agreement are terminated as of the
Effective Date. For the avoidance of doubt, Sanofi hereby waives any right it has to indemnification by the MK Entities under any and all product liability lawsuits pending as of the Effective Date, and the MK Entities hereby waive any right they
have to indemnification by the Sanofi Entities under any and all product liability lawsuits pending as of the Effective Date. 

  

	13.	Dispute Resolution. In the event of any dispute arising out of or relating to this Agreement or either Party’s rights or obligations hereunder, the provisions of Article 14 of the LCA shall apply and
govern the procedure and resolution of any such dispute. In the event multiple disputes arise out of or relating to any combination of this Agreement, the Parties may join any or all such disputes, and the provisions of Article 14 of the LCA shall
continue to apply and govern the procedure and resolution of any such dispute. 

  

					
	 	  	SETTLEMENT AGREEMENT	  	PAGE 7  

 CONFIDENTIAL 

 

	14.	General Provisions. 

  

	 	(a)	Intervening Events. If the performance of any part of this Agreement by either Party (other than making payment when due) is prevented, restricted, interfered with or delayed by any reason or cause beyond the
reasonable control of such Party (including: fire, flood, embargo, power shortage or failure, acts of war, insurrection, riot, terrorism, strike, lockout or other labor disturbance (save where such strike, lockout, or other labor disturbance is
initiated by the employees of the Party which seeks to rely on this clause), acts of God or any acts, omissions or delays in acting of the other Party) (an “Intervening Event”), the Party so affected shall, upon giving written
notice to the other Party, be excused from such performance to the extent of such Intervening Event, provided that the affected Party shall use its substantial efforts to avoid or remove such causes of non-performance and shall continue performance
with the utmost dispatch whenever such causes are removed. If either Party becomes aware that such an Intervening Event has occurred, is imminent or likely, it will immediately notify the other Party. The Party which is subject to such Intervening
Event shall exert all reasonable efforts to overcome it. Such Party will keep the other informed as to the progress of overcoming such Intervening Event. 

  

	 	(b)	Performance by Affiliates/Related Parties. To the extent that this Agreement imposes obligations on Affiliates or Related Parties of a Party, such Party agrees to cause its Affiliates or Related Parties to
perform such obligation. Either Party may use one or more of its Affiliates or Related Parties to perform its obligation hereunder, provided that the Parties will remain liable hereunder for the prompt payment and performance of all their respective
obligations hereunder. 

  

	 	(c)	Modification. No amendment or modification of any provision of this Agreement shall be effective unless in a prior writing signed by all of MannKind and Sanofi. No provision of this Agreement shall be varied,
contradicted or explained by any oral agreement, course of dealing or performance or any other matter not set forth in an agreement in writing and signed by the Parties hereto. 

 

	 	(d)	No Circumvention of this Agreement. The Parties, on behalf of themselves and all of their Affiliates and Related Parties, agree that none of them shall enter into any arrangements, formal or informal, with the
purpose of circumventing the intent of the terms and conditions of this Agreement. 

  

	 	(e)	Third Party Beneficiaries. The Parties agree that each Sanofi Entity, each MK Entity and each of their respective Related Parties are intended third party beneficiaries of the releases and covenants provided
under this Agreement. 

  

	 	(f)	Incorporation of Recitals. The Parties hereby incorporate each of the Recitals stated above as material provisions of this Agreement. 

 

	 	(g)	Language. The language of this Agreement and all activities to be pursued under this Agreement is English. Any and all documents proffered by one Party to the other in fulfillment of any provision of this
Agreement shall only be in compliance if in English. Any translation of this Agreement in another language shall be deemed for convenience only and shall never prevail over the original English version. This Agreement is established in the English
language. 

  

					
	 	  	SETTLEMENT AGREEMENT	  	PAGE 8  

 CONFIDENTIAL 
  

 

	 	(h)	Interpretation. The captions to this Agreement are not a part of this Agreement but are included for convenience of reference and shall not affect its meaning or interpretation. In this Agreement: (a) the
word “including” shall be deemed to be followed by the phrase “without limitation” or like expression; (b) the word “or” means “and/or” unless the context dictates otherwise because the subject of the
conjunction are mutually exclusive; (c) the words “herein,” “hereof” and “hereunder” and other words of similar import refer to this Agreement as a whole and not to any particular Article or Section or other
subdivision; (d) references in this Agreement to “days” shall mean calendar days; (e) the singular shall include the plural and vice versa; and (f) masculine, feminine and neuter pronouns and expressions shall be
interchangeable. Each accounting term used herein that is not specifically defined herein shall have the meaning given to it under IFRS, or if not defined by IFRS, the meaning applied to it by Sanofi in preparing its publicly reported financial
statements, in each case, consistently applied, but only to the extent consistent with its usage and the other definitions in this Agreement. 

  

	 	(i)	Counterparts; Electronic or Facsimile Signatures. This Agreement may be executed in any number of counterparts, each of which shall be an original, but all of which together shall constitute one instrument. This
Agreement may be executed and delivered electronically or by facsimile and upon such delivery such electronic or facsimile signature will be deemed to have the same effect as if the original signature had been delivered to the other Party.

  

	 	(j)	Taxes. Each Party shall bear its own tax liability in connection with this Agreement and shall make any report, payment or withholding as instructed or required by any regulatory or taxing authority.

  

	 	(k)	Applicable Law. This Agreement shall be governed by and construed in accordance with the laws of the State of New York without regard to principles of conflicts of law. 

 

	 	(l)	Notices. Any notice or communication required or permitted under this Agreement shall be in writing in the English language, delivered personally, sent by facsimile (and promptly confirmed by personal delivery,
registered or certified mail or overnight courier), sent by internationally-recognized courier or sent by registered or certified mail, postage prepaid to the following addresses of the Parties (or such other address for a Party as may be at any
time thereafter specified by like notice): 

 If to MannKind, as follows: 

MannKind Corporation 
 25134 Rye
Canyon Loop, Suite 300 
 Valencia, CA 91355 

Facsimile: 661-775-2081 

Attention: General Counsel 

  

					
	 	  	SETTLEMENT AGREEMENT	  	PAGE 9  

 CONFIDENTIAL 
  

with a copy to: 
 Quinn Emanuel
Urquhart & Sullivan LLP 
 865 S. Figueroa St., 10th Floor 

Los Angeles, CA 90017 

Facsimile: 213-443-3100 

Attention: Joseph M. Paunovich, Esq. 

If to Sanofi, as follows: 

sanofi-aventis U.S. LLC 
 55
Corporate Drive 
 Mailstop: 55A-515A 

Bridgewater, NJ 08807 

Facsimile: 908-927-8623 

Attention: General Counsel, NA 

Stacy Silkworth, Esq. 

Christopher Liwski, Esq. 
 with
a copy to: 
 Weil, Gotshal & Manges LLP 

767 Fifth Avenue 
 New York, NY
10153 
 Facsimile: (212) 310-8000 

Attention: Yehudah L. Buchweitz, Esq. 

Jeffrey D. Osterman, Esq. 
 Any
such notice shall be deemed to have been given: (a) when delivered if personally delivered; (b) on the next Business Day after dispatch if sent by confirmed facsimile or by internationally-recognized overnight courier; or (c) on the
third Business Day following the date of mailing if sent by mail or nationally recognized courier. 
 [SIGNATURE
PAGE FOLLOWS] 

  

					
	 	  	SETTLEMENT AGREEMENT	  	PAGE 10  

 IN WITNESS WHEREOF, the Parties have caused this Agreement to be duly executed and delivered by their
respective duly authorized representatives on the day and year first above written. 
 sanofi-aventis U.S. LLC 

 

			
	By:	 	 /s/ Susan A. Manardo

	 Name:
	 	Susan A. Manardo
	 Title:
	 	VP & Head, N.A. Litigation & Investigations

 [Signature Page to Settlement Agreement] 

  

 IN WITNESS WHEREOF, the Parties have caused this Agreement to be duly executed and delivered by their
respective duly authorized representatives on the day and year first above written. 
 MannKind Corporation 

 

			
	By:	 	 /s/ Matthew Pfeffer

	 Name:
	 	Matthew Pfeffer
	 Title:
	 	Chief Executive Officer

 Technosphere International C.V. 

By: MannKind Corporation, its General Partner 
  

			
	By:	 	 /s/ Matthew Pfeffer

	 Name:
	 	Matthew Pfeffer
	 Title:
	 	Chief Executive Officer

 MannKind Netherlands B.V. 
  

			
	By:	 	 /s/ Matthew Pfeffer

	 Name:
	 	Matthew Pfeffer
	 Title:
	 	Managing Director

 [Signature Page to Settlement Agreement] 

  

 EXHIBIT A 

Pay-Off Letter 

[Attached] 

  

 EXHIBIT B 

Form of Press Release 
  

 
 Company Contact: 

Rose Alinaya 
 SVP, Finance 

661-775-5300 
 ralinaya@mannkindcorp.com 

MANNKIND AND SANOFI REACH AGREEMENT ON AFREZZA® 

VALENCIA, Calif., November 9, 2016 (GLOBE NEWSWIRE) — MannKind Corporation (NASDAQ and TASE:MNKD) today announced that MannKind and Sanofi
have entered into an agreement with the following terms: 
  

	 	•	 	The promissory note and security agreement between MannKind and Aventisub LLC, a Sanofi affiliate, are terminated, with Aventisub agreeing to forgive the full outstanding loan balance of $71.56 million.

  

	 	•	 	MannKind is also relieved from its obligation to pay $0.5 million in previously uncharged costs related to the collaboration. 

  

	 	•	 	Sanofi will purchase $10.2 million worth of insulin from MannKind in early December as part of its preexisting commitment to purchase insulin following termination of the collaboration and MannKind’s exercise of a
“put” option. 

  

	 	•	 	The balance of the insulin “put” option ($30.6 million) is accelerated with Sanofi completing the cash payment of $30.6 million to MannKind by January 9, 2017. This payment will be made without MannKind
being required to deliver any insulin to Sanofi. 

  

	 	•	 	All issues arising out of the license and collaboration agreement, the supply agreement, the promissory note, the security agreement and the transition agreement are resolved. 

About MannKind Corporation 
 MannKind Corporation (NASDAQ
and TASE: MNKD) focuses on the discovery, development and commercialization of therapeutic products for patients with diseases such as diabetes. MannKind maintains a website at http://www.mannkindcorp.com to which MannKind regularly posts
copies of its press releases as well as additional information about MannKind. Interested persons can subscribe on the MannKind website to e-mail alerts that are sent automatically when MannKind issues press releases, files its reports with the
Securities and Exchange Commission or posts certain other information to the website. 

  

 EXHIBIT C 

Agreed Form of Statement 
 On
November 9, 2016, MannKind and Sanofi reached an agreement to resolve all the outstanding contractual issues related to Afrezza. We refer you to the press release dated November 9, 2016. 

If MannKind is asked about claims, disputes or liabilities: 

The parties have mutually released one another from any and all potential claims arising out of the license and collaboration agreement, the supply agreement,
the promissory note, the security agreement and the transition agreement. 

  

 EXHIBIT D 

Outstanding Transition Agreement Deliverables/Transition Activities 

 

					
	 Transition Agreement

Reference
	  	 Deliverable/Transition Activity
	  	Delivery/Completion
Deadline
	Exhibit C, Deliverable Number 30	  	Regulatory Reporting of Sample Distribution (XML files) reporting period up to and including April 4th, 2016 filed to the NDA.	  	April 30, 2017
			
	Exhibit E, Transition Service Number 11	  	 Sanofi to honor 2016 Sanofi Savings Cards for patients who have registered with Sanofi on or before April 4, 2016 until December

31, 2016.
	  	December 31, 2016
			
	Exhibit E, Transition Service Number 28	  	Sanofi to work with Veteran Affairs (VA) to remove the Sanofi Afrezza NDCs from the Federal Supply Schedule (FSS).	  	January 1, 2017

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