Document:

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                                                                   EXHIBIT 10.15

                                                                      *LOAN1000*

                            MASTER SECURITY AGREEMENT
                    dated as of August 20, 2003 (" Agreement")

         THIS AGREEMENT is between General Electric Capital Corporation
(together with its successors and assigns, if any, "Secured Party") and Barrier
Therapeutics, Inc. ("Debtor"). Secured Party has an office at 401 Meritt 7 Suite
23,Norwalk,CT 06851-1177. Debtor is a corporation organized and existing under
the laws of the state of Delaware ("the State"). Debtor's mailing address and
chief place of business is 600 College Road East, Plainsboro, NI 08540.

1.       CREATION OF SECURITY INTEREST.

         Debtor grants to Secured Party, its successors and assigns, a security
interest in and against all property listed on any collateral schedule now or in
the future annexed to or made a part of this Agreement ("Collateral Schedule"),
and in and against all additions, attachments, accessories and accessions to
such property, all substitutions, replacements or exchanges therefor, and all
insurrance and/or other proceeds thereof (all such property is individually and
collectively called the "Collateral"). This security interest is given to secure
the payment and performance of all debts, obligations and liabilities of any
kind whatsoever of Debtor to Secured Party, now existing or arising in the
future, including but not limited to the payment and performance of certain
Promissory Notes from time to time identified on any Collateral Schedule
(collectively "Notes" and each a "Note"), and any renewals, extensions and
modifications of such debts, obligations and liabilities (such Notes, debts,
obligations and liabilities are called the "Indebtedness").

2.       REPRESENTATIONS, WARRANTIES AND COVENANTS OF DEBTOR.

         Debtor represents, warrants and covenants as of the date of this
Agreement and as of the date of each Collateral Schedule that:

         (a)      Debtor's exact legal name is as set forth in the preamble of
this Agreement and Debtor is, and will remain, duly organized, existing and in
good standing under the laws of the State set forth in the preamble of this
Agreement, has its chief executive offices at the location specified in the
preamble, and is, and will remain, duly qualified and licensed in every
jurisdiction wherever necessary to carry on its business and operations;

         (b)      Debtor has adequate power and capacity to enter into, and to
perform its obligations under this Agreement, each Note and any other documents
evidencing, or given in connection with, any of the Indebtedness (all of the
foregoing are called, the "Debt Documents");

         (c)      This Agreement and the other Debt Documents have been duly
authorized, executed and delivered by Debtor and constitute legal, valid and
binding agreements enforceable in accordance with their terms, except to the
extent that the enforcement of remedies may be limited under applicable
bankruptcy and insolvency laws;

         (d)      No approval, consent or withholding of objections is required
from any governmental authority or instrumentality with respect to the entry
into, or performance by Debtor of any of the Debt Documents, except any already
obtained;

         (e)      The entry into, and performance by, Debtor of the Debt
Documents will not (i) violate any of the organizational documents of Debtor or
any judgment, order, law or regulation applicable to Debtor, or (ii) result in
any breach of or constitute a default under any contract to which Debtor is a
party, or result in the creation of any lien, claim or encumbrance on any of
Debtor's property (except for liens in favor of Secured Party) pursuant to any
indenture, mortgage, deed of trust, bank loan, credit agreement, or other
agreement or instrument to which Debtor is a party;

         (f)      There are no suits or proceedings pending in court or before
any commission, board or other administrative agency against or affecting Debtor
which could, in the aggregate, have a material adverse effect on Debtor, its
business or operations, or its ability to perform its obligations under the Debt
Documents, nor does Debtor have reason to believe that any such suits or
proceedings are threatened;

         (g)      All financial statement delivered to Secured Party in
connection with the Indebtedness have been prepared in Accordance with generally
accepted accounting principles, and since the date of the most recent financial
statement, there  has been no material adverse change in Debtors financial
condition;

         (h)      The Collateral is not, and will not be, used by Debtor for
personal, family or household purposes;

         (i)      The Collateral is, and will remain, in good condition and
repair and Debtor will not be negligent in its care and use;

         (j)      Debtor is, and will remain, the sole and lawful owner, and in
possession of, the Collateral, and has the sole right and lawful authority to
grant the security interest described in this Agreement;

         (k)      The Collateral is, and will remain, free and clear of all
liens, claims and encumbrances of any kind whatsoever, except for (i) liens in
favor of Secured Party, (ii) liens for taxes not yet due or for taxes being
contested in good faith and which do not involve, in the judgment of Secured
Party, any risk of the sale, forfaiture or loss of any of the Collateral, and
(iii) inchoate materialmen's, mechanic's, repairmen's and similar liens arising
by operation of law in the normal course of business for amounts which are
not delinquent (all of such liens are called "Permitted Liens"); and

         (l)      Debtor is and will remain in full compliance with all laws and
regulations applicable to it including, without limitation, (i) ensuring that no
person who owns a controlling interest in or otherwise controls Debtor is or
shall be (Y) listed on the Specially Designated Nationals and Blocked Person
List maintained by the Office of Foreign Assets Control ("OFAC"), Department of
the Treasury, and/or any other similar lists maintained by OFAC pursuant to any
authorizing statute, Executive Order or regulation or (Z) a person designated
under Section 1(b), (c) or (d) of Executive Order No. 13224 (September 23,
2001), any related enabling legislation or any other similar Executive Orders,
and (ii) compliance with all applicable Bank Secrecy Act ("BSA") laws,
regulations and government guidance on BSA compliance and on the prevention and
detection of money laundering violations.

3.     COLLATERAL.

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         (a) Until the declaration of any default, Debtor shall remain in
possession of the Collateral; except that Secured Party shall have the right to
possess (i) any chattel paper or instrument that constitutes a part of the
Collateral, and (ii) any other Collateral in which Secured Party's security
interest may be perfected only by possession. Secured Party may inspect any of
the Collateral during normal business hours after giving Debtor reasonable prior
notice. If Secured Party asks, Debtor will promptly notify Secured Party in
writing of the location of any Collateral.

         (b) Debtor shall (i) use the Collateral only in its trade or business,
(ii) maintain all of the Collateral in good operating order and repair, normal
wear and tear excepted, (iii) use and maintain the Collateral only in compliance
with manufacturers recommendations and all applicable laws, and (iv) keep all of
the Collateral free and clear of all liens, claims and encumbrances (except for
Permitted Liens).

         (c) Secured Party does not authorize and Debtor agrees it shall not (i)
part with possession of any of the Collateral (except to Secured Party or for
maintenance and repair), (ii) remove any of the Collateral from the continental
United States, or (iii) sell, rent, lease, mortgage, license, grant a security
interest in or otherwise transfer or encumber (except for Permitted Liens) any
of the Collateral.

         (d) Debtor shall pay promptly when due all taxes, license fees,
assessments and public and private charges levied or assessed on any of the
Collateral, on its use, or on this Agreement or any of the other Debt Documents.
At its option, Secured Party may discharge taxes, liens, security interests or
other encumbrances at any time levied or placed on the Collateral and may pay
for the maintenance, insurance and preservation of the Collateral and effect
compliance with the terms of this Agreement or any of the other Debt Documents.
Debtor agrees to reimburse Secured Party, on demand, all coats and expenses
incurred by Secured Party in connection with such payment or performance and
agrees that such reimbursement obligation shall constitute Indebtedness.

         (e) Debtor shall, at all times, keep accurate and complete records of
the Collateral, and Secured Party shall have the right to inspect and make
copies of all of Debtor's books and records relating to the Collateral during
normal business hours, after giving Debtor reasonable prior notice.

         (f) Debtor agrees and acknowledges that any third person who may at any
time possess all or any portion of the Collateral shall be deemed to hold, and
shall hold, the Collateral as the agent of, and as pledge holder for, Secured
Party. Secured Party may at any time give notice to any third person described
in the proceeding sentence that such third person is holding the Collateral as
the agent of, and as pledge holder for, the Secured Party.

4.       INSURANCE.

         (a) Debtor shall at all times bear the entire risk of any loss, theft,
damage to, or destruction of, any of the Collateral from any cause whatsoever.

         (b) Debtor agrees to keep the Collateral insured against loss or damage
by fire and extended coverage perils, theft, burglary, and for any or all
Collateral which are vehicles, for risk of loss by collision, and if requested
by Secured Party, against such other risks as Secured Party may reasonably
require. The insurance coverage shall be in an amount no less than the full
replacement value of the Collateral, and deductible amounts, insurers and
policies shall be acceptable to Secured Party. Debtor shall deliver to Secured
Party policies or certificates of insurance evidencing such coverage. Each
policy shall name Secured Party as a loss payee, shall provide for coverage to
Secured Party regardless of the breach by Debtor of any warranty or
representation made therein, shall not be subject to co-insurance, and shall
provide that coverage may not be canceled or altered by the insurer except upon
thirty (30) days prior written notice to Secured Party. Debtor appoints Secured
Party as its attorney-in-fact to make proof of loss, claim for insurance and
adjustments with insurers, and to receive payment of and execute or endorse all
documents, checks or drafts in connection with insurance payments. Secured Party
shall not act as Debtor's attorney-in-fact unless Debtor is in default. Proceeds
of insurance shall be applied, at the option of Secured Party, to repair or
replace the Collateral or to reduce any of the Indebtedness.

5.       REPORTS.

         (a) Debtor shall promptly notify Secured Party of (i) any change in the
name of Debtor, (ii) any change in the state of its incorporation or
registration, (iii) any relocation of its chief executive offices, (iv) any
relocation of any of the Collateral, (v) any of the Collateral being lost,
stolen, missing, destroyed, materially damaged or worn out, or (vi) any lien,
claim or encumbrance other than Permitted Liens attaching to or being made
against any of the Collateral.

         (b) Debtor will deliver to Secured Party Debtor's complete financial
statements, certified by a recognised firm of certified public accountants,
within ninety (90) days of the close of each fiscal year of Debtor. If Secured
Party requests, Debtor will deliver to Secured Party copies of Debtor's
quarterly financial reports certified by Debtor's chief financial officer,
within ninety (90) days after the close of each of Debtor's fiscal quarter.
Debtor will deliver to Secured Party copies of all Forms 10-K and 10-Q, if any,
within 30 days after the dates on which they are filed with the Securities and
Exchange Commission.

6.       FURTHER ASSURANCES.

         (a) Debtor shall, upon request of Secured Party, furnish to Secured
Party such further information, execute and deliver to Secured Party such
documents and instruments (including, without limitation, Uniform Commercial
Code financing statements) and shall do such other acts and things as Secured
Party may at any time reasonably request relating to the perfection or
protection of the security interest created by this Agreement or for the purpose
of carrying out the intent of this Agreement. Without limiting the foregoing,
Debtor shall co-operate and do all acts deemed necessary or advisable by Secured
Party to continue in Secured Party a perfected first security interest in the
Collateral, and shall obtain and furnish to Secured Party any subordinations,
releases, landlord waivers, lessor waivers, mortgagee waivers, or control
agreements, and similar documents as may be from time to time requested by, and
in form and substance satisfactory to, Secured Party.

         (b) Debtor authorizes Secured Party to file a financing statement and
amendments thereto describing the Collateral and containing any other
information required by the applicable Uniform Commercial Code. Debtor
irrevocably grants to Secured Party the power to sign Debtor's name and
generally to act on behalf of Debtor to execute and file applications for title,
transfers of title, financing statements, notices of lien and other documents
pertaining to any or all of the Collateral; this power is coupled with Secured
Party's interest in the Collateral. Debtor shall, if any certificate of title be
required or permitted by law for any of the Collateral, obtain and promptly
deliver to Secured Party such certificate showing the lien of this Agreement
with respect to the Collateral. Debtor notifies its prior authorization for
Secured Party to file financing statements and amendments thereto describing the
Collateral and containing any other information required by the Uniform
Commercial Code if filed prior the date hereof.

         (c) Debtor shall indemnify and defend the Secured Party, its successors
and assigns, and their respective directors, officers and employees, from and
against all claims, actions and suits (including, without limitation, related
attorneys' fees) of any kind whatsoever arising, directly or indirectly, in
connection with any of the Collateral.
<PAGE>

7.       DEFAULT AND REMEDIES.

         (a)      Debtor shall be to default under this Agreement and each of
the other Debt Documents if:

                  (i)      Debtor breaches its obligation to pay when due any
installment or other amount due or coming due under any of the Debt Documents;

                  (ii)     Debtor, without the prior written consent of Secured
Party, attempts to or does sell, rent, lease, license, mortgage, grant a
security interest in, or otherwise transfer or encumber (except for Permitted
Liens) any of the Collateral;

                  (iii)    Debtor breaches any of its insurance obligations
under Section 4;

                  (iv)     Debtor breaches any of its other obligations under
any of the Debt Documents and fails to cure that breach within thirty (30) days
after written notice from Secured Party,

                  (v)      Any warranty, representation or statement made by
Debtor in any of the Debt Documents or otherwise in connection with any of the
Indebtedness shall be false or misleading in any material respect.

                  (vi)     Any of the Collateral a subjected to attachment,
execution, levy, seizure or confiscation in any legal proceeding or otherwise,
or if any legal or administrative proceeding is commenced against Debtor or any
of the Collateral, which in the good faith judgment of Secured Party subjects
any of the Collateral to a material risk of attachment, execution, levy, seizure
or confiscation and no bond a posted or protective order obtained to negate such
risk.

                  (vii)    Debtor breaches or is in default under any other
agreement between Debtor and Secured Party;

                  (viii)   Debtor or my guarantor or other obligor far any of
the Indebtedness (collectively "GUARANTOR") dissolves, terminates its existence,
becomes insolvent or ceases to do business as a going concern;

                  (ix)     If Debtor or any Guarantor is a natural person,
Debtor or any such Guarantor dies or becomes incompetent;

                  (x)      A receiver is appointed for all or of any put of the
property of Debtor or any Guarantor, or Debtor or any Guarantor makes any
assignment for the benefit of creditors;

                  (xi)     Debtor or any Guarantor files a petition under any
bankruptcy, insolvency or similar law, or any such petition is filed against
Debtor or any Guarantor and is not dismissed within forty-five (45) days;

                  (xii)    Debtor's improper filing of an amendment or
termination statement relating to a filed financing statement describing the
Collateral: or

                  (xiii)   Debtor defaults under any other material Obligation
for (A) borrowed money, (B) the deferred purchase price of property or (C)
payments due under any lease agreement.

         (b)      If Debtor it in default, the Secured Party, at its option, may
declare any or all of the Indebtedness to be immediately due and payable,
without demand or notice to Debtor or any Guarantor. The accelerated obligations
and liabilities shall bear interest (both before and after any judgment) until
paid in full at the lower eighteen percent(18%) per annum or the maximum rate
not prohibited by applicable law.

         (c)      After default, Secured Party shall have all of the rights and
remedies of a Secured Party under the Uniform Commercial Code, and under any
other applicable law. Without limiting the foregoing. Secured Party Shall have
the right to (i) notify any account debtor of Debtor or any obligor on any
instrument which constitutes part of the Collateral to make payment to the
Secured Party, (ii) with or without legal process, enter any premises where the
Collateral may be and take possession of and remove the Collateral from the
premises or store it on the premises, (iii) sell the Collateral at public or
private sale, in whole or in part, and have the right to bid and purchase at
said sale, or (iv) lease or otherwise dispose of all or part of the Collateral,
applying proceeds from such disposition to the obligations then in default. If
requested by Secured Party, Debtor shall promptly assemble the Collateral and
make it available to Secured Party at a place to be designated by Secured Party
which is reasonably convenient to both parties. Secured Party may also render
any or all of the Collateral unusable at the Debtor's premises and may dispose
of such Collateral on such premises without liability for rent or costs. Any
notice that Secured Party is required to give to Debtor under the Uniform
Commercial Code of the time and place of any public sale or the time after which
any private sale or other intended disposition of the Collateral is to be made
shall be deemed to constitute reasonable notice if such notice is given to the
last known address of Debtor at least five (5) days prior to such action.

         (d)      Proceeds from any sale or lease or other disposition shall be
applied; first, to all costs of repossession, storage, and disposition including
without limitation attorneys', appraisers', and auctioneers fees; second, to
discharge the obligations then in default; third, to discharge any other
Indebtedness of Debtor to Secured Party, whether as obligor, endorser,
guarantor, surety or indemnitor, fourth, to expenses incurred in paying or
settling Hens and claims against the Collateral; and lastly, to Debtor, if there
exists any surplus. Debtor shall remain fully liable for any deficiency.

         (e)      Debtor agrees to pay all reasonable attorneys' fees and other
costs incurred by Secured Party in connection with the enforcement, assertion,
defense or preservation of Secured Party's rights and remedies under this
Agreement, or if prohibited by law, such lesser sum as may be permitted. Debtor
further agrees that such fees and costs shall constitute Indebtedness.

         (f)      Secured Party's rights and remedies under this Agreement or
otherwise arising are cumulative and may be exercised singularly or
concurrently. Neither the failure nor any delay on the part of the Secured Party
to exercise any right, power or privilege under this Agreement shall operate as
a waiver, nor shall any single or partial excercise of any right, power or
privilege preclude any other or further exercise of that or any other right,
power or privilege. SECURED PARTY SHALL NOT BE DEEMED TO HAVE WAIVED ANY OF ITS
RIGHTS UNDER THIS AGREEMENT OR UNDER ANY OTHER AGREEMENT. INSTRUMENT OR PAPER
SIGNED BY DEBTOR UNLESS SUCH WAIVER IS EXPRESSED IN WRITING AND SIGNED BY
SECURED PARTY. A waiver on any one occasion shall not be construed as a bar to
or waiver of any right or remedy on any future occasion.

         (g)      DEBTOR AND SECURED PARTY UNCONDITIONALLY WAIVE THEIR RIGHTS TO
A JURY TRIAL OF ANY CLAIM OR CAUSE OF ACTION BASED UPON OR ARISING OUT OF THIS
AGREEMENT, ANY OF THE OTHER DEBT DOCUMENTS, ANY OF THE INDEBTEDNESS SECURED
HEREBY. ANY DEALINGS BETWEEN DEBTOR AND SECURED PARTY RELATING TO THE SUBJECT
MATTER OF THIS TRANSACTION OR ANY RELATED TRANSACTIONS, AND/OR THE RELATIONSHIP
THAT IS BEING ESTABLISHED BETWEEN DEBTOR AND SECURED PARTY. THE SCOPE OF THIS
WAIVER IS INTENDED TO BE ALL ENCOMPASSING OF ANY AND ALL DISPUTES THAT MAY BE
<PAGE>

FILED IN ANY COURT. THIS WAIVER IS IRREVOCABLE. THIS WAIVER MAY NOT BE MODIFIED
EITHER ORALLY OR IN WRITING. THE WAIVER ALSO SHALL APPLY TO ANY SUBSEQUENT
AMENDMENTS, RENEWALS, SUPPLEMENTS OR MODIFICATIONS TO THIS AGREEMENT, ANY OTHER
DEBT DOCUMENTS, OR TO ANY OTHER DOCUMENTS OR AGREEMENTS RELATING TO THIS
TRANSACTION OR ANY RELATED TRANSACTION. THIS AGREEMENT MAY BE FILED AS A WRITTEN
CONSENT TO A TRIAL BY THE COURT.

8.       MISCELLANEOUS.

         (a)      This Agreement, any Note and/or any of the other Debt
Documents may be assigned, in whole or in part, by Secured Party without notice
to Debtor, and Debtor agrees not to assert against any such assignee, or
assignee's assigns, any defense, set-off, recoupment claim or counterclaim which
Debtor has or may at any time have against Secured Party for any reason
whatsoever. Debtor agrees that if Debtor receives written notice of [ILLEGIBLE]
assignment from Secured Party. Debtor will pay all amounts payable under any
assigned Debt Documents to such assignee or as instructed by Secured Party.
Debtor also agrees to confirm in writing receipt of the notice of assignment as
may be reasonably requested by Secured Party or assignee.

         (b)      All notices to be given in connection with this Agreement
shall be in writing, shall be addressed to the parties at their respective
addresses set forth in this Agreement (unless and until a different address may
be specified in a written notice to the other party), and shall be deemed given
(i) on the date of receipt if delivered in hand or by facsimile transmission,
(ii) on the next business day after being sent by express mail, and (iii) on the
fourth business day after being sent by regular, registered or certified mail.
As used herein, the term "business day" shall mean and include any day other
than Saturdays, Sundays, or other days on which commercial banks in New York,
New York are required or authorized to be closed.

         (c)      Secured Party may correct patent errors and fill in all blanks
in this Agreement or in any Collateral Schedule consistent with the agreement of
the parties.

         (d)      Time is of the essence of this Agreement. This Agreement shall
be binding, jointly and severally, upon all parties described as the "Debtor"
and their respective heirs, executors, representatives, successors and assigns,
and shall inure to the benefit of Secured Party, its successors and assigns.

         (e)      This Agreement and its Collateral Schedules constitute the
entire agreement between the parties with respect to the subject matter of this
Agreement and supersede all prior understandings (whether written, verbal or
implied) with respect to such subject matter. THIS AGREEMENT AND ITS COLLATERAL
SCHEDULES SHALL NOT BE CHANGED OR TERMINATED ORALLY OR BY COURSE OF CONDUCT. BUT
ONLY BY A WRITING SIGNED BY BOTH PARTIES. Section headings contained in this
Agreement have been included for convenience only, and shall not affect the
construction or interpretation of this Agreement.

         (f)      This Agreement shall continue in full force and effect until
all of the Indebtedness has been indefeasibly paid in full to Secured Party or
its assignee. The surrender, upon payment or otherwise, of any Note or any of
the other documents evidencing any of the Indebtedness shall not affect the
right of Secured Party to retain the Collateral for such other Indebtedness as
may then exist or as it may be reasonably contemplated will exist in the future.
This Agreement shall automatically be reinstated if Secured Party is ever
required to return or restore the payment of all or any portion of the
Indebtedness (all as though such payment had never been made).

         (g)      THIS AGREEMENT AND THE RIGHTS AND OBLIGATIONS OF THE PARTIES
HEREUNDER SHALL IN ALL RESPECTS BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH,
THE INTERNAL LAWS OF THE STATE OF CONNECTICUT (WITHOUT REGARD TO THE CONFLICT OF
LAWS PRINCIPLES OF SUCH STATE), INCLUDING ALL MATTERS OF CONSTRUCTION, VALIDITY
AND PERFORMANCE, REGARDLESS OF THE LOCATION OF THE COLLATERAL.

         IN WITNESS WHEREOF, Debtor and Secured Party, intending to be legally
bound hereby, have duly executed this Agreement in one or more counterparts,
each of which shall be deemed to be an original, as of the day and year first
aforesaid.

SECURED PARTY:                                  DEBTOR:

GENERAL ELECTRIC CAPITAL CORPORATION            BARRIER THERAPEUTICS, INC.

By:     /s/ Diane Hernandez                     By:   /s/ ANNE VANLENT
        ----------------------------                  --------------------------
Name:   DIANE HERNANDEZ                         Name: ANNE VANLENT
Title:  Vice President                          Title: EVP CFO

<PAGE>

                                    AMENDMENT

         THIS AMENDMENT is made as of the 3 day of September, 2003, between
General Electric Capital Corporation ("Secured Party") and Barrier Therapeutics,
Inc. ("Debtor") in connection with that certain Master Security Agreement, dated
as of August 20, 2003 ("Agreement"). The terms of this Amendment are hereby
incorporated into the Agreement as though fully set forth therein. Section
references below refer to the section numbers of the Agreement. The Agreement is
hereby amended as follows:

         5.       REPORTS.

         Subsection (b) is hereby amended with the following:

         "(b) Debtor will deliver to Secured Party financial statements as
         follows. If Debtor is a privately held company, then Debtor agrees to
         provide monthly financial statements, certified by Debtor's president
         or chief financial officer including a balance sheet, statement of
         operations and cash flow statement within 30 days of each month end and
         its complete audited annual financial statements, certified by a
         recognized firm of certified public accountants, within 120 days of
         fiscal year end or at such time as Debtor's Board of Directors receives
         the audit. If Debtor is a publicly held company, then Debtor agrees to
         provide quarterly unaudited statements and annual audited statements,
         certified by a recognized firm of certified public accountants, within
         10 days after the statements are provided to the Securities and
         Exchange Commission ("SEC"). All such statements are to be prepared
         using generally accepted accounting principles ("GAAP") and, if Debtor
         is a publicly held company, are to be in compliance with SEC
         requirements."

         7.       DEFAULT AND REMEDIES.

         Subsection (a) is hereby amended with the following:

         "(a) Debtor shall be in default under this Agreement and each of the
         other Debt Documents if:

         (i) Debtor breaches its obligation to pay when due any installment or
         other amount due or coming due under any of the Debt Documents;

         (ii) Debtor, without the prior written consent of Secured Party,
         attempts to or does sell, rent, lease, license, mortgage, grant a
         security interest in, or otherwise transfer or encumber (except for
         Permitted Liens) any of the Collateral;

         (iii) Debtor breaches any of its insurance obligations under Section 4;

         (iv) Debtor breaches any of its other obligations under any of the Debt
         Documents and fails to cure that breach within thirty (30) days after
         written notice from Secured Party;

         (v) Any warranty, representation or statement made by Debtor in any of
         the Debt Documents or otherwise in connection with any of the
         Indebtedness shall be false or misleading in any material respect;

         (vi) Any of the Collateral is subjected to attachment, execution, levy,
         seizure or confiscation in any legal proceeding or otherwise, or if any
         legal or administrative proceeding is

<PAGE>

         commenced against Debtor or any of the Collateral, which in the good
         faith judgment of Secured Party subjects any of the Collateral to a
         material risk of attachment, execution, levy, seizure or confiscation
         and no bond is posted or protective order obtained to negate such risk;

         (vii) Debtor breaches or is in default under any other agreement
         between Debtor and Secured Party;

         (viii) Debtor or any guarantor or other obligor for any of the
         Indebtedness (collectively "GUARANTOR") dissolves, terminates its
         existence, becomes insolvent or ceases to do business as a going
         concern;

         (ix) If Debtor or any Guarantor is a natural person, Debtor or any such
         Guarantor dies or becomes incompetent;

         (x) A receiver is appointed for all or of any part of the property of
         Debtor or any Guarantor, or Debtor or any Guarantor makes any
         assignment for the benefit of creditors;

         (xi) Debtor or any Guarantor files a petition under any bankruptcy,
         insolvency or similar law, or any such petition is filed against Debtor
         or any Guarantor and is not dismissed within forty-five (45) days;

         (xii) Debtor's improper filing of an amendment or termination statement
         relating to a filed financing statement describing the Collateral; or

         (xiii) Debtor defaults under any other material obligation for (A)
         borrowed money, (B) the deferred purchase price of property or (C)
         payments due under any lease agreement.

         (xiv) At any time during the term of this Agreement Debtor sells more
         than 50% of its interest in the company to another corporation or
         business or all or substantially all of its assets without Secured
         Party's prior written consent, such consent not to be unreasonably
         withheld by Secured Party.

         (xv) There is a material adverse change in the Debtor's financial
         condition as determined solely by Secured Party."

         TERMS USED, BUT NOT OTHERWISE DEFINED HEREIN SHALL HAVE THE MEANINGS
GIVEN TO THEM IN THE AGREEMENT. EXCEPT AS EXPRESSLY AMENDED HEREBY, THE
AGREEMENT SHALL REMAIN IN FULL FORCE AND EFFECT. IF THERE IS ANY CONFLICT
BETWEEN THE PROVISIONS OF THE AGREEMENT AND THIS AMENDMENT, THEN THIS AMENDMENT
SHALL CONTROL.

         IN WITNESS WHEREOF, the parties hereto have executed this Amendment
simultaneously with the Agreement by signature of their respective authorized
representative set forth below.

GENERAL ELECTRIC CAPITAL CORPORATION          BARRIER THERAPEUTICS, INC.

By: /s/ Diane Hernandez                       By: /s/ Anne M. Vanlent
   ------------------------                      -----------------------
Name: Diane Hernandez                         Name: ANNE M. VANLENT
Title: Vice President                         Title: EVP & CFO

<PAGE>

                          EQUIPMENT CONCENTRATION RIDER

         BARRIER THERAPEUTICS, INC. ("Customer"), on or before July 31, 2004,
         shall cause the composition and mix of Equipment financed after August
         20, 2003 under the Master Security Agreement dated as of August 20,
         2003 between Customer and General Electric Capital Corporation to
         conform to and meet the following concentration requirements
         (hereinafter "Concentration Requirements") for each class of Equipment
         (hereinafter "Equipment Class") as identified and set forth below.
         Customer herein represents and warrants that it shall maintain each
         such Equipment Class and its respective Concentration Requirement from
         and after such above referenced date and continuing thereafter to the
         end of the term:

         EQUIPMENT CLASS                               CONCENTRATION REQUIREMENT

         Computers, networking equipment,
         Lab and office furniture, hoods, Safes,
         & similar:                                    Maximum of 80%

         Soft costs (leaseholds, software,             Maximum of 20%
         & similar):

Accepted and Agreed:

BARRIER THERAPEUTICS, INC.

By: /s/ Anne M. Vanlent
   -------------------------
Title: EVP & CFO
Date: September 3, 2003Exhibit 4.1

                             FIXED RATE SENIOR NOTE

REGISTERED                                                  REGISTERED
No. FXR                                                     U.S. $
                                                            CUSIP:

     Unless this certificate is presented by an authorized representative of
The Depository Trust Company (55 Water Street, New York, New York) to the
issuer or its agent for registration of transfer, exchange or payment, and any
certificate issued is registered in the name of Cede & Co. or such other name
as requested by an authorized representative of The Depository Trust Company
and any payment is made to Cede & Co., ANY TRANSFER, PLEDGE OR OTHER USE HEREOF
FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL since the registered
owner hereof, Cede & Co., has an interest herein.

                                      A-1
<PAGE>

                                 MORGAN STANLEY
                    SENIOR GLOBAL MEDIUM-TERM NOTE, SERIES C

                PERFORMANCE LEVERAGED UPSIDE SECURITIES ("PLUS")

                             PLUS DUE JULY 30, 2006
                            MANDATORILY EXCHANGEABLE
                     FOR AN AMOUNT PAYABLE IN U.S. DOLLARS
                     BASED ON THE VALUE OF COMMON STOCK OF
                 FIFTEEN COMPANIES IN THE GOLD MINING INDUSTRY

<TABLE>
<S>                                 <C>                           <C>                         <C>

ORIGINAL ISSUE DATE:          INITIAL REDEMPTION           INTEREST RATE: None          MATURITY DATE:
   February 10, 2004             DATE: N/A                                                 See "Maturity Date"
                                                                                           below.

INTEREST ACCRUAL              INITIAL REDEMPTION           INTEREST PAYMENT             OPTIONAL
   DATE: N/A                     PERCENTAGE: N/A              DATES: N/A                   REPAYMENT
                                                                                           DATE(S): N/A

SPECIFIED CURRENCY:           ANNUAL REDEMPTION            INTEREST PAYMENT             APPLICABILITY OF
   U.S. dollars                  PERCENTAGE                   PERIOD: N/A                  MODIFIED
                                 REDUCTION: N/A                                            PAYMENT UPON
                                                                                           ACCELERATION: See
                                                                                           "Alternate Exchange
                                                                                           Calculation in Case of
                                                                                           an Event of Default"
                                                                                           below.

IF SPECIFIED                  REDEMPTION NOTICE            APPLICABILITY OF             If yes, state Issue Price:
   CURRENCY OTHER                PERIOD: N/A                  ANNUAL INTEREST              N/A
   THAN U.S. DOLLARS,                                         PAYMENTS: N/A
   OPTION TO ELECT
   PAYMENT IN U.S.
   DOLLARS: N/A

EXCHANGE RATE                 TAX REDEMPTION                                            ORIGINAL YIELD TO
   AGENT: N/A                    AND PAYMENT OF                                            MATURITY: N/A
                                 ADDITIONAL
                                 AMOUNTS: N/A

OTHER PROVISIONS:             If yes, state Initial Offering
   See below                  Date: N/A
</TABLE>

Maturity Date........................   July 30, 2006, subject to extension in
                                        the event of a Market Disruption Event
                                        on any Basket Valuation Date (as
                                        defined below).

                                        If due to a Market Disruption Event or
                                        otherwise, any Basket Valuation Date
                                        occurs on or after July 28, 2006, the
                                        Maturity Date shall be the second
                                        Trading Day

                                      A-2
<PAGE>

                                        following the final Basket Valuation
                                        Date. See "Basket Valuation Dates"
                                        below.

                                        In the event that the Maturity Date of
                                        the PLUS is postponed due to
                                        postponement of any Basket Valuation
                                        Date as described in the immediately
                                        preceding paragraph, the Issuer shall
                                        give notice of such postponement and,
                                        once it has been determined, of the
                                        date to which the Maturity Date has
                                        been rescheduled (i) to the holder of
                                        this PLUS by mailing notice of such
                                        postponement by first class mail,
                                        postage prepaid, to the holder's last
                                        address as it shall appear upon the
                                        registry books, (ii) to the Trustee by
                                        telephone or facsimile confirmed by
                                        mailing such notice to the Trustee by
                                        first class mail, postage prepaid, at
                                        its New York office and (iii) to The
                                        Depository Trust Company (the
                                        "Depositary") by telephone or facsimile
                                        confirmed by mailing such notice to the
                                        Depositary by first class mail, postage
                                        prepaid. Any notice that is mailed in
                                        the manner herein provided shall be
                                        conclusively presumed to have been duly
                                        given, whether or not the holder of
                                        this PLUS receives the notice. The
                                        Issuer shall give such notice as
                                        promptly as possible, and in no case
                                        later than (i) with respect to notice
                                        of postponement of the Maturity Date,
                                        the Business Day immediately following
                                        July 28, 2006, and (ii) with respect to
                                        notice of the date to which the
                                        Maturity Date has been rescheduled, the
                                        Business Day immediately following the
                                        actual Basket Valuation Date for
                                        determining the Final Average Basket
                                        Value (as defined below).

Denominations........................   $10 and integral multiples thereof

Payment at Maturity..................   At maturity, upon delivery of this PLUS
                                        to the Trustee, the Issuer shall pay
                                        with respect to each $10 principal
                                        amount of this PLUS an amount in cash
                                        equal to (i) if the Final Average
                                        Basket Value is greater than the
                                        Initial Basket Value (as defined
                                        below), the lesser of (a) $10 plus the
                                        Leveraged Upside Payment (as defined
                                        below) and (b) the Maximum Payment at
                                        Maturity (as defined below) or (ii) if
                                        the Final Average Basket Value is less
                                        than or equal to the Initial Basket
                                        Value, $10 times the Basket Performance
                                        Factor (as defined below).

                                        The Issuer shall, or shall cause the
                                        Calculation Agent to, (i) provide
                                        written notice to the Trustee and to
                                        the

                                      A-3
<PAGE>

                                        Depositary of the amount of cash to be
                                        delivered with respect to each $10
                                        principal amount of this PLUS, on or
                                        prior to 10:30 a.m. on the Trading Day
                                        preceding the Maturity Date (but if
                                        such Trading Day is not a Business Day,
                                        prior to the close of business on the
                                        Business Day preceding the Maturity
                                        Date), and (ii) deliver the aggregate
                                        cash amount due with respect to this
                                        PLUS to the Trustee for delivery to the
                                        holder of this PLUS on the Maturity
                                        Date.

Leveraged Upside Payment .............  The product of (i) $10 and (ii) 200%
                                        and (iii) the Basket Percent Increase
                                        (as defined below).

Maximum Payment at Maturity...........  $14.60

Basket Stocks........................   The Basket Stocks are the stocks of the
                                        fifteen issuers set forth in the table
                                        below. The table also indicates the
                                        ticker symbol for each Basket Stock,
                                        the U.S. exchange on which each Basket
                                        Stock is listed and the Exchange Ratio
                                        with respect to each Basket Stock, each
                                        as determined on February 5, 2004.

             Issuer of                          Ticker              Exchange
             Basket Stock                       Symbol  Exchange    Ratio
             ------------                       ------  --------    -----

             Agnico-Eagle Mines Limited         AEM      NYSE
             Barrick Gold Corporation           ABX      NYSE
             Bema Gold Corporation              BGO      AMEX
             Coeur D'Alene Mines
                Corporation                     CDE      NYSE
             Glamis Gold Ltd.                   GLG      NYSE
             Gold Fields Limited                GFI*     NYSE
             Goldcorp Inc.                      GG       NYSE
             Golden Star Resources Ltd.         GSS      AMEX
             Harmony Gold Mining
                Company Limited                 HMY*     NYSE
             Hecla Mining Company               HL       NYSE
             IAMGold Corporation                IAG      AMEX
             Kinross Gold Corporation           KGC      NYSE
             Meridian Gold Inc.                 MDG      NYSE
             Newmont Mining Corporation         NEM      NYSE
             Randgold Resources Ltd.            GOLD*    NASDAQ
             ---------
             * Trades as American Depositary Shares

Basket...............................   The Basket is initially composed of the
                                        common stock of the fifteen companies
                                        in the gold mining industry listed in
                                        the table under "Basket Stocks" above
                                        and shall consist of a number of shares
                                        of each Basket Stock equal to the
                                        Exchange Ratio with respect to such
                                        Basket Stock.

                                      A-4
<PAGE>

Exchange Ratio.......................   The Exchange Ratio for each Basket
                                        Stock is set forth in the table under
                                        "Basket Stocks" above and shall remain
                                        constant for the term of this PLUS,
                                        subject to adjustment for certain
                                        corporate and other events relating to
                                        the issuer of that Basket Stock. See
                                        "Adjustments to the Exchange Ratios"
                                        below.

Basket Percent Increase..............   A fraction, the numerator of which is
                                        the Final Average Basket Value minus
                                        the Initial Basket Value and the
                                        denominator of which is the Initial
                                        Basket Value.

Basket Performance Factor............   A fraction, the numerator of which is
                                        the Final Average Basket Value and the
                                        denominator of which is the Initial
                                        Basket Value.

Final Average Basket Value...........   The arithmetic average of the Basket
                                        Values on each of the Basket Valuation
                                        Dates.

Basket Valuation Dates...............   July 25, 2006, July 26, 2006 and July
                                        27, 2006; provided that if any such
                                        date is not a Trading Day or if there
                                        is a Market Disruption Event on such
                                        date, the Basket Valuation Dates shall
                                        be the first three Trading Days
                                        occurring on or after July 25, 2006 on
                                        which no Market Disruption Event
                                        occurs.

Initial Basket Value.................   $10.00

Basket Value.........................   The Basket Value on any date shall
                                        equal the sum of the products of the
                                        Closing Price and the Exchange Ratio
                                        for each Basket Stock, each determined
                                        as of such date by the Calculation
                                        Agent.

Closing Price........................   The Closing Price for one share of a
                                        Basket Stock (or one unit of any other
                                        security for which a Closing Price must
                                        be determined) on any Trading Day (as
                                        defined below) means:

                                        o    if a Basket Stock (or any such
                                             other security) is listed or
                                             admitted to trading on a national
                                             securities exchange, the last
                                             reported sale price, regular way,
                                             of the principal trading session
                                             on such day on the principal
                                             United States securities exchange
                                             registered under the Securities
                                             Exchange Act of 1934, as amended
                                             (the "Exchange Act"), on which
                                             such Basket Stock (or any such
                                             other security) is listed or
                                             admitted to trading,

                                      A-5
<PAGE>

                                        o    if a Basket Stock (or any such
                                             other security) is a security of
                                             the Nasdaq National Market (and
                                             provided that the Nasdaq National
                                             Market is not then a national
                                             securities exchange), the Nasdaq
                                             official closing price published
                                             by The Nasdaq Stock Market, Inc.
                                             on such day, or

                                        o    if a Basket Stock (or any such
                                             other security) is not listed or
                                             admitted to trading on any
                                             national securities exchange or a
                                             security of the Nasdaq National
                                             Market but is included in the OTC
                                             Bulletin Board Service (the "OTC
                                             Bulletin Board") operated by the
                                             National Association of Securities
                                             Dealers, Inc. (the "NASD"), the
                                             last reported sale price of the
                                             principal trading session on the
                                             OTC Bulletin Board on such day.

                                        If a Basket Stock (or any such other
                                        security) is listed or admitted to
                                        trading on any national securities
                                        exchange or is a security of the Nasdaq
                                        National Market but the last reported
                                        sale price or Nasdaq official closing
                                        price, as applicable, is not available
                                        pursuant to the preceding sentence,
                                        then the Closing Price for one share of
                                        such Basket Stock (or one unit of any
                                        such other security) on any Trading Day
                                        shall mean the last reported sale price
                                        of the principal trading session on the
                                        over-the-counter market as reported on
                                        the Nasdaq National Market or the OTC
                                        Bulletin Board on such day. If, because
                                        of a Market Disruption Event (as
                                        defined below) or otherwise, the last
                                        reported sale price or Nasdaq official
                                        closing price, as applicable, for a
                                        Basket Stock (or any such other
                                        security) is not available pursuant to
                                        either of the two preceding sentences,
                                        then the Closing Price for any Trading
                                        Day shall be the mean, as determined by
                                        the Calculation Agent, of the bid
                                        prices for such Basket Stock (or any
                                        such other security) obtained from as
                                        many recognized dealers in such
                                        security, but not exceeding three, as
                                        shall make such bid prices available to
                                        the Calculation Agent. Bids of MS & Co.
                                        or any of its affiliates may be
                                        included in the calculation of such
                                        mean, but only to the extent that any
                                        such bid is the highest of the bids
                                        obtained. The term "security of the
                                        Nasdaq National Market" shall include a
                                        security included in any successor to
                                        such system, and the term "OTC Bulletin
                                        Board Service" shall include any
                                        successor service thereto.

Trading Day..........................   A day, as determined by the Calculation
                                        Agent, on which trading is generally
                                        conducted on the New York Stock

                                      A-6
<PAGE>

                                        Exchange (the "NYSE"), the American
                                        Stock Exchange LLC, the Nasdaq National
                                        Market, the Chicago Mercantile Exchange
                                        and the Chicago Board of Options
                                        Exchange and in the over-the-counter
                                        market for equity securities in the
                                        United States.

Calculation Agent....................   Morgan Stanley & Co. Incorporated and
                                        its successors ("MS & Co.").

                                        All determinations made by the
                                        Calculation Agent shall be at the sole
                                        discretion of the Calculation Agent and
                                        shall, in the absence of manifest
                                        error, be conclusive for all purposes
                                        and binding on the holder of this PLUS
                                        and the Issuer.

                                        All calculations with respect to the
                                        Payment at Maturity, if any, will be
                                        made by the Calculation Agent and will
                                        be rounded to the nearest one
                                        billionth, with five ten-billionths
                                        rounded upward (e.g., .8765432105
                                        would be rounded to .876543211);
                                        all dollar amounts related to
                                        determination of the amount of cash
                                        payable for each $10 principal amount
                                        of this PLUS shall be rounded to the
                                        nearest ten-thousandth, with five one
                                        hundred-thousandths rounded upwards
                                        (e.g., .76545 would be rounded up to
                                        .7655); and all dollar amounts paid on
                                        the aggregate number of PLUS shall be
                                        rounded to the nearest cent, with
                                        one-half cent rounded upward.

Market Disruption Event..............   "Market Disruption Event" means, with
                                        respect to any Basket Stock (and, in
                                        the case of a Basket Stock that trades
                                        as American Depositary Shares ("ADS"),
                                        the ordinary shares of the issuer of
                                        such Basket Stock):

                                           (i) a suspension, absence or
                                           material limitation of trading of
                                           such Basket Stock or ordinary shares
                                           of the issuer of such Basket Stock
                                           that trades as ADS on the primary
                                           market for such Basket Stock or
                                           ordinary shares of the issuer of
                                           such Basket Stock that trades as ADS
                                           for more than two hours of trading
                                           or during the one-half hour period
                                           preceding the close of the principal
                                           trading session in such market; or a
                                           breakdown or failure in the price
                                           and trade reporting systems of the
                                           primary market for such Basket Stock
                                           or ordinary shares of the issuer of
                                           such Basket Stock that trades as ADS
                                           as a result of which the reported
                                           trading prices for such Basket Stock
                                           or ordinary

                                      A-7
<PAGE>

                                           shares of the issuer of such Basket
                                           Stock that trades as ADS during the
                                           last one-half hour preceding the
                                           close of the principal trading
                                           session in such market are
                                           materially inaccurate; or the
                                           suspension, absence or material
                                           limitation of trading on the primary
                                           market for trading in options
                                           contracts related to such Basket
                                           Stock or ordinary shares of the
                                           issuer of such Basket Stock that
                                           trades as ADS, if available, during
                                           the one-half hour period preceding
                                           the close of the principal trading
                                           session in the applicable market, in
                                           each case as determined by the
                                           Calculation Agent in its sole
                                           discretion; and

                                           (ii) a determination by the
                                           Calculation Agent in its sole
                                           discretion that any event described
                                           in clause (i) above materially
                                           interfered with the ability of
                                           Morgan Stanley or any of its
                                           affiliates to unwind or adjust all
                                           or a material portion of the hedge
                                           position in such Basket Stock with
                                           respect to the PLUS.

                                        For purposes of determining whether a
                                        Market Disruption Event has occurred:
                                        (1) a limitation on the hours or number
                                        of days of trading shall not constitute
                                        a Market Disruption Event if it results
                                        from an announced change in the regular
                                        business hours of the relevant
                                        exchange, (2) a decision to permanently
                                        discontinue trading in the relevant
                                        options contract shall not constitute a
                                        Market Disruption Event, (3)
                                        limitations pursuant to NYSE Rule 80A
                                        (or any applicable rule or regulation
                                        enacted or promulgated by the NYSE, any
                                        other United States self- regulatory
                                        organization, the Securities and
                                        Exchange Commission or any other
                                        relevant authority of scope similar to
                                        NYSE Rule 80A as determined by the
                                        Calculation Agent) on trading during
                                        significant market fluctuations shall
                                        constitute a suspension, absence or
                                        material limitation of trading, (4) a
                                        suspension of trading in options
                                        contracts on any Basket Stock or
                                        ordinary shares of the issuer of such
                                        Basket Stock that trades as ADS by the
                                        primary securities market trading in
                                        such options, if available, by reason
                                        of (x) a price change exceeding limits
                                        set by such securities exchange or
                                        market, (y) an imbalance of orders
                                        relating to such contracts or (z) a
                                        disparity in bid and ask quotes
                                        relating to such contracts shall
                                        constitute a suspension, absence or
                                        material limitation of trading in
                                        options contracts related to such
                                        Basket Stock or ordinary shares of the
                                        issuer of

                                      A-8
<PAGE>

                                        such Basket Stock that trades as ADS
                                        and (5) a suspension, absence or
                                        material limitation of trading on the
                                        primary securities market on which
                                        options contracts related to any Basket
                                        Stock or ordinary shares of the issuer
                                        of such Basket Stock that trades as ADS
                                        are traded shall not include any time
                                        when such securities market is itself
                                        closed for trading under ordinary
                                        circumstances.

Alternate Exchange Calculation
in Case of an Event of Default.......   In case an event of default with
                                        respect to the PLUS shall have occurred
                                        and be continuing, the amount declared
                                        due and payable for each $10 principal
                                        amount of this PLUS upon any
                                        acceleration of this PLUS shall be
                                        determined by the Calculation Agent and
                                        shall be an amount in cash equal to the
                                        Payment at Maturity calculated using
                                        the Basket Value as of the date of
                                        acceleration as the Final Average
                                        Basket Value.

                                        If the maturity of the PLUS is
                                        accelerated because of an event of
                                        default as described above, the Issuer
                                        shall, or shall cause the Calculation
                                        Agent to, provide written notice to the
                                        Trustee at its New York office, on
                                        which notice the Trustee may
                                        conclusively rely, and to the
                                        Depositary of the aggregate cash amount
                                        due with respect to each $10 principal
                                        amount of this PLUS as promptly as
                                        possible and in no event later than two
                                        Business Days after the date of
                                        acceleration.

Adjustments to the Exchange Ratios....  The Exchange Ratio with respect to a
                                        Basket Stock shall be adjusted as
                                        follows:

                                        1. If a Basket Stock (or, in the case
                                        of a Basket Stock that trades as ADS,
                                        the ordinary shares of the issuer of
                                        such Basket Stock) is subject to a
                                        stock split or reverse stock split,
                                        then once such split has become
                                        effective, the Exchange Ratio for such
                                        Basket Stock shall be adjusted to equal
                                        the product of the prior Exchange Ratio
                                        for such Basket Stock and the number of
                                        shares issued in such stock split or
                                        reverse stock split with respect to one
                                        share of such Basket Stock; provided,
                                        however, that, with respect to a Basket
                                        Stock that trades as ADS, if (and to
                                        the extent that) the issuer of such
                                        Basket Stock or the depositary for the
                                        ADS has adjusted the number of ordinary
                                        shares represented by each ADS so that
                                        the price of the ADS would not be
                                        affected by such stock split or reverse
                                        stock split, no adjustment to the
                                        Exchange Ratio shall be made.

                                      A-9
<PAGE>

                                        2. If a Basket Stock (or, in the case
                                        of a Basket Stock that trades as ADS,
                                        the ordinary shares of the issuer of
                                        such Basket Stock) is subject (i) to a
                                        stock dividend (issuance of additional
                                        shares of such Basket Stock or ordinary
                                        shares of the issuer of a Basket Stock
                                        that trades as ADS) that is given
                                        ratably to all holders of shares of
                                        such Basket Stock or (ii) to a
                                        distribution of such Basket Stock, or
                                        ordinary shares of the issuer of a
                                        Basket Stock that trades as ADS, as a
                                        result of the triggering of any
                                        provision of the corporate charter of
                                        the issuer of such Basket Stock, then
                                        once the dividend has become effective
                                        and such Basket Stock is trading
                                        ex-dividend, the Exchange Ratio for
                                        such Basket Stock shall be adjusted so
                                        that the new Exchange Ratio for such
                                        Basket Stock shall equal equal the
                                        prior Exchange Ratio for such Basket
                                        Stock plus the product of (i) the
                                        number of shares issued with respect to
                                        one share of such Basket Stock and (ii)
                                        the prior Exchange Ratio for such
                                        Basket Stock; provided, however, that,
                                        with respect to a Basket Stock traded
                                        as ADS, if (and to the extent that) the
                                        issuer of such Basket Stock or the
                                        depositary for the ADS has adjusted the
                                        number of ordinary shares represented
                                        by each ADS so that the price of the
                                        ADS would not be affected by such stock
                                        dividend or stock distribution, no
                                        adjustment to the Exchange Ratio shall
                                        be made.

                                        3. There shall be no adjustments to the
                                        Exchange Ratio for any Basket Stock to
                                        reflect cash dividends or other
                                        distributions paid with respect to the
                                        Basket Stock (or, in the case of a
                                        Basket Stock that trades as ADS, the
                                        ordinary shares of the issuer of such
                                        Basket Stock) other than distributions
                                        described in clauses (i), (iv) and (v)
                                        of paragraph 5 below and Extraordinary
                                        Dividends as described below. For a
                                        Basket Stock that is traded as ADS,
                                        cash dividends or other distributions
                                        paid on the ordinary shares represented
                                        by such ADS shall not be considered
                                        Extraordinary Dividends unless such
                                        cash dividends or other distributions,
                                        when passed through to the holder of
                                        such shares, would constitute
                                        Extraordinary Dividends as described
                                        below. A cash dividend or other
                                        distribution with respect to a Basket
                                        Stock shall be deemed to be an
                                        "Extraordinary Dividend" if such
                                        dividend or other distribution exceeds
                                        the immediately preceding
                                        non-Extraordinary Dividend for such
                                        Basket Stock by an amount equal to at
                                        least 10% of the Closing Price of such
                                        Basket Stock (as adjusted for any

                                     A-10
<PAGE>

                                        subsequent corporate event requiring an
                                        adjustment hereunder, such as a stock
                                        split or reverse stock split) by an
                                        amount equal to at least 10% of the
                                        Closing Price of such Basket Stock on
                                        the Trading Day preceding the "ex-
                                        dividend date" (that is, the day on and
                                        after which transactions in a Basket
                                        Stock on the primary United States
                                        organized securities exchange or
                                        trading system for such Basket Stock no
                                        longer carry the right to receive that
                                        cash dividend or other cash
                                        distribution) for the payment of such
                                        Extraordinary Dividend. If an
                                        Extraordinary Dividend occurs with
                                        respect to a Basket Stock, the Exchange
                                        Ratio with respect to such Basket Stock
                                        shall be adjusted on the ex-dividend
                                        date with respect to such Extraordinary
                                        Dividend so that the new Exchange Ratio
                                        for such Basket Stock shall equal the
                                        product of (i) the then current
                                        Exchange Ratio for such Basket Stock
                                        and (ii) a fraction, the numerator of
                                        which is the Closing Price of the
                                        Basket Stock on the Trading Day
                                        preceding the ex-dividend date, and
                                        the denominator of which is the amount
                                        by which the Closing Price of the
                                        Basket Stock on the Trading Day
                                        preceding the ex-dividend date exceeds
                                        the Extraordinary Dividend Amount. The
                                        "Extraordinary Dividend Amount" with
                                        respect to an Extraordinary Dividend
                                        for a Basket Stock shall equal (i) in
                                        the case of cash dividends or other
                                        distributions that constitute regular
                                        dividends, the amount per share of such
                                        Extraordinary Dividend minus the amount
                                        per share of the immediately preceding
                                        non-Extraordinary Dividend for such
                                        Basket Stock or (ii) in the case of
                                        cash dividends or other distributions
                                        that do not constitute regular
                                        dividends, the amount per share of such
                                        Extraordinary Dividend. To the extent
                                        an Extraordinary Dividend is not paid
                                        in cash, the value of the non-cash
                                        component shall be determined by the
                                        Calculation Agent, whose determination
                                        shall be conclusive. A distribution on
                                        a Basket Stock described in clause (i),
                                        (iv) or (v) of paragraph 5 below that
                                        also constitutes an Extraordinary
                                        Dividend shall cause an adjustment to
                                        the Exchange Ratio pursuant only to
                                        clause (i), (iv) or (v) of paragraph 5,
                                        as applicable.

                                        4. If the issuer of a Basket Stock
                                        issues rights or warrants to all
                                        holders of a Basket Stock to subscribe
                                        for or purchase such Basket Stock at an
                                        exercise price per share less than the
                                        Closing Price of such Basket Stock on
                                        both (i) the date the exercise price of
                                        such rights or warrants is

                                     A-11
<PAGE>

                                        determined and (ii) the expiration date
                                        of such rights or warrants, and if the
                                        expiration date of such rights or
                                        warrants precedes the maturity of the
                                        PLUS, then the Exchange Ratio for such
                                        Basket Stock shall be adjusted to equal
                                        the product of the prior Exchange Ratio
                                        for such Basket Stock and a fraction,
                                        the numerator of which shall be the
                                        number of shares of such Basket Stock
                                        outstanding immediately prior to the
                                        issuance of such rights or warrants
                                        plus the number of additional shares of
                                        such Basket Stock offered for
                                        subscription or purchase pursuant to
                                        such rights or warrants and the
                                        denominator of which shall be the
                                        number of shares of such Basket Stock
                                        outstanding immediately prior to the
                                        issuance of such rights or warrants
                                        plus the number of additional shares of
                                        such Basket Stock which the aggregate
                                        offering price of the total number of
                                        shares of such Basket Stock so offered
                                        for subscription or purchase pursuant
                                        to such rights or warrants would
                                        purchase at the Closing Price on the
                                        expiration date of such rights or
                                        warrants, which shall be determined by
                                        multiplying such total number of shares
                                        offered by the exercise price of such
                                        rights or warrants and dividing the
                                        product so obtained by such Closing
                                        Price.

                                        5. Any of the following shall
                                        constitute a Reorganization Event: (i)
                                        there occurs any reclassification or
                                        change of a Basket Stock (or, in the
                                        case of a Basket Stock that trades as
                                        ADS, the ordinary shares of the issuer
                                        of such Basket Stock), including,
                                        without limitation, as a result of the
                                        issuance of any tracking stock by the
                                        issuer of such Basket Stock, (ii) the
                                        issuer of a Basket Stock or any
                                        surviving entity or subsequent
                                        surviving entity of the issuer of such
                                        Basket Stock (an "Issuer Successor")
                                        has been subject to a merger,
                                        combination or consolidation and is not
                                        the surviving entity, (iii) any
                                        statutory exchange of securities of the
                                        issuer of a Basket Stock or any Issuer
                                        Successor with another corporation
                                        occurs (other than pursuant to clause
                                        (ii) above), (iv) the issuer of a
                                        Basket Stock is liquidated, (v) the
                                        issuer of a Basket Stock issues to all
                                        of its shareholders equity securities
                                        of an issuer other than the issuer of
                                        such Basket Stock (other than in a
                                        transaction described in clause (ii),
                                        (iii) or (iv) above) (a "Spinoff
                                        Event") or (vi) a tender or exchange
                                        offer or going-private transaction is
                                        consummated for all the outstanding
                                        shares of such Basket Stock. If any
                                        Reorganization Event occurs, in each
                                        case as a result of

                                     A-12
<PAGE>

                                        which the holders of a Basket Stock are
                                        entitled to receive stock, other
                                        securities or other property or assets
                                        (including, without limitation, cash or
                                        other classes of securities of the
                                        issuer of such Basket Stock and
                                        including (x) in the case of the
                                        issuance of tracking stock, the
                                        reclassified share of the Basket Stock,
                                        (y) in the case of a Spin-off Event,
                                        the share of the Basket Stock with
                                        respect to which the spun-off security
                                        was issued and (z) in the case of any
                                        other Reorganization Event where the
                                        Basket Stock continues to be held by
                                        the holders receiving such
                                        distribution, the Basket Stock)
                                        (collectively, "Exchange Property")
                                        with respect to or in exchange for such
                                        Basket Stock, then in lieu of using the
                                        product of the Closing Price and the
                                        Exchange Ratio for such Basket Stock to
                                        calculate the Basket Value on any date,
                                        the Calculation Agent shall use the
                                        Exchange Property Value on such date.
                                        The Exchange Property Value at any date
                                        means (i) for any cash received per
                                        share of Basket Stock, the amount of
                                        cash received per share of Basket Stock
                                        as adjusted by the applicable Exchange
                                        Ratio for such Basket Stock on the date
                                        of such Reorganization Event, (ii) for
                                        any property other than cash or
                                        securities received in such
                                        distribution, the market value, as
                                        determined by the Calculation Agent, as
                                        of the date of receipt, of such
                                        Exchange Property received for each
                                        share of Basket Stock, as adjusted by
                                        the Exchange Ratio for such Basket
                                        Stock on the date of such
                                        Reorganization Event, (iii) for any
                                        security received in any such
                                        distribution, an amount equal to the
                                        Closing Price, as of the date on which
                                        the Exchange Property Value is
                                        determined, per share of such security
                                        multiplied by the quantity of such
                                        security received for each share of
                                        Basket Stock, as adjusted by the
                                        Exchange Ratio for such Basket Stock on
                                        the date of the initial distribution of
                                        such Exchange Property (such
                                        as-adjusted quantity, a "New Exchange
                                        Ratio") and (iv) if the Exchange
                                        Property was distributed with respect
                                        to, rather than in exchange for, a
                                        Basket Stock, an amount equal to the
                                        Closing Price, as of the date on which
                                        the Exchange Property Value is
                                        determined, for such Basket Stock
                                        multiplied by the Exchange Ratio as of
                                        the date on which the Exchange Property
                                        Value is determined. Holders of PLUS
                                        shall not receive any interest accrued
                                        on the cash component of any Exchange
                                        Property. Any New Exchange Ratio shall
                                        also be subject to the adjustments set
                                        forth in paragraphs 1 through 5 hereof.

                                     A-13
<PAGE>

                                        For purposes of paragraph 5 above, in
                                        the case of a consummated tender or
                                        exchange offer or going-private
                                        transaction involving Exchange Property
                                        of a particular type, Exchange Property
                                        shall be deemed to include the amount
                                        of cash or other property paid by the
                                        offeror in the tender or exchange offer
                                        with respect to such Exchange Property
                                        (in an amount determined on the basis
                                        of the rate of exchange in such tender
                                        or exchange offer or going-private
                                        transaction). In the event of a tender
                                        or exchange offer or a going-private
                                        transaction with respect to Exchange
                                        Property in which an offeree may elect
                                        to receive cash or other property,
                                        Exchange Property shall be deemed to
                                        include the kind and amount of cash and
                                        other property received by offerees who
                                        elect to receive cash.

                                        If a Closing Price for a Basket Stock
                                        is no longer available for a Basket
                                        Stock for whatever reason, including
                                        the liquidation of the issuer of such
                                        Basket Stock or the subjection of such
                                        issuer to a proceeding under any
                                        applicable bankruptcy, insolvency or
                                        other similar law, then the value of
                                        such Basket Stock shall equal zero for
                                        so long as no Closing Price is
                                        available. There shall be no
                                        substitution for any such Basket Stock.

                                        With respect to a Basket Stock that is
                                        traded as ADS, in the event that the
                                        issuer of such Basket Stock or the
                                        depositary for such ADS elects, in the
                                        absence of any of the events described
                                        above, to change the number of ordinary
                                        shares that are represented by such
                                        ADS, the Exchange Ratio for such Basket
                                        Stock on any Trading Day after the
                                        change becomes effective shall be
                                        proportionately adjusted.

                                        No adjustment to the Exchange Ratio for
                                        any Basket Stock shall be required
                                        unless such adjustment would require a
                                        change of at least .1% in the Exchange
                                        Ratio of such Basket Stock then in
                                        effect. The Exchange Ratio resulting
                                        from any of the adjustments specified
                                        above shall be rounded to the nearest
                                        one hundred-thousandth, with five
                                        one-millionths rounded upward.
                                        Adjustments to the Exchange Ratio of a
                                        Basket Stock shall be made up to and
                                        including the final scheduled Basket
                                        Valuation Date.

                                        No adjustments to the Exchange Ratio
                                        for any Basket Stock shall be required
                                        other than those specified above.

                                     A-14
<PAGE>

                                        The adjustments specified above do not
                                        cover all of the events that could
                                        affect the Closing Price of a Basket
                                        Stock, including, without limitation, a
                                        partial tender or exchange offer for a
                                        Basket Stock (or, in the case of a
                                        Basket Stock that trades as ADS, the
                                        ADS or the ordinary shares of the
                                        issuer of such Basket Stock).

                                        The Calculation Agent shall be solely
                                        responsible for the determination and
                                        calculation of any adjustments to any
                                        Exchange Ratio for a Basket Stock or
                                        method of calculating the Exchange
                                        Property Value and of any related
                                        determinations and calculations with
                                        respect to any distributions of stock,
                                        other securities or other property or
                                        assets (including cash) in connection
                                        with any corporate event described in
                                        paragraph 5 above, and its
                                        determinations and calculations with
                                        respect thereto shall be conclusive in
                                        the absence of manifest error.

                                        The Calculation Agent shall provide
                                        information as to any adjustments to
                                        any Exchange Ratio upon written request
                                        by any investor in the PLUS.

Treatment of PLUS for
United States Federal
Income Tax Purposes..................   The Issuer, by its sale of this PLUS,
                                        and the holder of this PLUS (and any
                                        successor holder of, or holder of a
                                        beneficial interest in, this PLUS), by
                                        its respective purchase hereof, agree
                                        (in the absence of an administrative
                                        determination or judicial ruling to the
                                        contrary) to characterize each $10
                                        principal amount of this PLUS for all
                                        tax purposes as a single financial
                                        contract with respect to the Basket
                                        that (i) requires the holder of this
                                        PLUS to pay to the Issuer at inception
                                        an amount equal to $10 and (ii)
                                        entitles the holder to receive at
                                        maturity an amount in cash based upon
                                        the performance of the Basket.

                                     A-15
<PAGE>

     Morgan Stanley (formerly known as Morgan Stanley Dean Witter & Co.), a
Delaware corporation (together with its successors and assigns, the "Issuer"),
for value received, hereby promises to pay to CEDE & Co., or registered
assignees, the principal sum of U.S.$
(UNITED STATES DOLLARS               ), on the Maturity Date specified above
(except to the extent redeemed or repaid prior to maturity) and to pay interest
thereon at the Interest Rate per annum specified above, from and including the
Interest Accrual Date specified above until the principal hereof is paid or
duly made available for payment weekly, monthly, quarterly, semiannually or
annually in arrears as specified above as the Interest Payment Period on each
Interest Payment Date (as specified above), commencing on the Interest Payment
Date next succeeding the Interest Accrual Date specified above, and on the
Maturity Date (or on any redemption or repayment date); provided, however, that
if the Interest Accrual Date occurs between a Record Date, as defined below,
and the next succeeding Interest Payment Date, interest payments shall commence
on the second Interest Payment Date succeeding the Interest Accrual Date to the
registered holder of this Note on the Record Date with respect to such second
Interest Payment Date; and provided, further, that if this Note is subject to
"Annual Interest Payments," interest payments shall be made annually in arrears
and the term "Interest Payment Date" shall be deemed to mean the first day of
March in each year.

     Interest on this Note shall accrue from and including the most recent date
to which interest has been paid or duly provided for, or, if no interest has
been paid or duly provided for, from and including the Interest Accrual Date,
until but excluding the date the principal hereof has been paid or duly made
available for payment. The interest so payable, and punctually paid or duly
provided for, on any Interest Payment Date shall, subject to certain exceptions
described herein, be paid to the person in whose name this Note (or one or more
predecessor Notes) is registered at the close of business on the date 15
calendar days prior to such Interest Payment Date (whether or not a Business
Day (as defined below)) (each such date, a "Record Date"); provided, however,
that interest payable at maturity (or any redemption or repayment date) shall
be payable to the person to whom the principal hereof shall be payable. As used
herein, "Business Day" means any day, other than a Saturday or Sunday, (a) that
is neither a legal holiday nor a day on which banking institutions are
authorized or required by law or regulation to close (x) in The City of New
York or (y) if this Note is denominated in a Specified Currency other than U.S.
dollars, euro or Australian dollars, in the principal financial center of the
country of the Specified Currency, or (z) if this Note is denominated in
Australian dollars, in Sydney and (b) if this Note is denominated in euro, that
is also a day on which the Trans-European Automated Real-time Gross Settlement
Express Transfer System ("TARGET") is operating (a "TARGET Settlement Day").

     Payment of the principal of this Note, any premium and the interest due at
maturity (or any redemption or repayment date), unless this Note is denominated
in a Specified Currency other than U.S. dollars and is to be paid in whole or
in part in such Specified Currency, shall be made in immediately available
funds upon surrender of this Note at the office or agency of the Paying Agent,
as defined on the reverse hereof, maintained for that purpose in the Borough of
Manhattan, The City of New York, or at such other paying agency as the Issuer
may determine, in U.S. dollars. U.S. dollar payments of interest, other than
interest due at maturity or on any date of redemption or repayment, shall be
made by U.S. dollar check mailed to the address of the person entitled thereto
as such address shall appear in the Note register. A holder of U.S. $10,000,000
(or the equivalent in a Specified Currency) or more in aggregate principal
amount of Notes having the same Interest

                                     A-16
<PAGE>

Payment Date, the interest on which is payable in U.S. dollars, shall be
entitled to receive payments of interest, other than interest due at maturity
or on any date of redemption or repayment, by wire transfer of immediately
available funds if appropriate wire transfer instructions have been received by
the Paying Agent in writing not less than 15 calendar days prior to the
applicable Interest Payment Date.

     If this Note is denominated in a Specified Currency other than U.S.
dollars, and the holder does not elect (in whole or in part) to receive payment
in U.S. dollars pursuant to the next succeeding paragraph, payments of
interest, principal or any premium with regard to this Note shall be made by
wire transfer of immediately available funds to an account maintained by the
holder hereof with a bank located outside the United States if appropriate wire
transfer instructions have been received by the Paying Agent in writing, with
respect to payments of interest, on or prior to the fifth Business Day after
the applicable Record Date and, with respect to payments of principal or any
premium, at least ten Business Days prior to the Maturity Date or any
redemption or repayment date, as the case may be; provided that, if payment of
interest, principal or any premium with regard to this Note is payable in euro,
the account must be a euro account in a country for which the euro is the
lawful currency, provided, further, that if such wire transfer instructions are
not received, such payments shall be made by check payable in such Specified
Currency mailed to the address of the person entitled thereto as such address
shall appear in the Note register; and provided, further, that payment of the
principal of this Note, any premium and the interest due at maturity (or on any
redemption or repayment date) shall be made upon surrender of this Note at the
office or agency referred to in the preceding paragraph.

     If so indicated on the face hereof, the holder of this Note, if
denominated in a Specified Currency other than U.S. dollars, may elect to
receive all or a portion of payments on this Note in U.S. dollars by
transmitting a written request to the Paying Agent, on or prior to the fifth
Business Day after such Record Date or at least ten Business Days prior to the
Maturity Date or any redemption or repayment date, as the case may be. Such
election shall remain in effect unless such request is revoked by written
notice to the Paying Agent as to all or a portion of payments on this Note at
least five Business Days prior to such Record Date, for payments of interest,
or at least ten calendar days prior to the Maturity Date or any redemption or
repayment date, for payments of principal, as the case may be.

     If the holder elects to receive all or a portion of payments of principal
of, premium, if any, and interest on this Note, if denominated in a Specified
Currency other than U.S. dollars, in U.S. dollars, the Exchange Rate Agent (as
defined on the reverse hereof) shall convert such payments into U.S. dollars.
In the event of such an election, payment in respect of this Note shall be
based upon the exchange rate as determined by the Exchange Rate Agent based on
the highest bid quotation in The City of New York received by such Exchange
Rate Agent at approximately 11:00 a.m., New York City time, on the second
Business Day preceding the applicable payment date from three recognized
foreign exchange dealers (one of which may be the Exchange Rate Agent unless
such Exchange Rate Agent is an affiliate of the Issuer) for the purchase by the
quoting dealer of U.S. dollars for the Specified Currency of U.S. dollars for
settlement on such payment date in the amount of the Specified Currency payable
in the absence of such an election to such holder and at which the applicable
dealer commits to execute a contract. If such bid quotations are not available,
such payment shall be made in the Specified Currency. All currency exchange
costs shall be borne by the holder of this Note by deductions from such
payments.

                                     A-17
<PAGE>

     Reference is hereby made to the further provisions of this Note set forth
on the reverse hereof, which further provisions shall for all purposes have the
same effect as if set forth at this place.

     Unless the certificate of authentication hereon has been executed by the
Trustee referred to on the reverse hereof by manual signature, this Note shall
not be entitled to any benefit under the Senior Indenture, as defined on the
reverse hereof, or be valid or obligatory for any purpose.

                                     A-18
<PAGE>

     IN WITNESS WHEREOF, the Issuer has caused this Note to be duly executed.

DATED: February 10, 2004                       MORGAN STANLEY

                                               By:
                                                  ------------------------------
                                                  Name:
                                                  Title:

TRUSTEE'S CERTIFICATE
  OF AUTHENTICATION

This is one of the Notes referred
    to in the within-mentioned
    Senior Indenture.

JPMORGAN CHASE BANK,
    as Trustee

By:
   -------------------------------
   Authorized Officer

                                     A-19
<PAGE>

                              REVERSE OF SECURITY

     This Note is one of a duly authorized issue of Senior Global Medium-Term
Notes, Series C, having maturities more than nine months from the date of issue
(the "Notes") of the Issuer. The Notes are issuable under an Amended and
Restated Senior Indenture, dated as of May 1, 1999, between the Issuer and
JPMorgan Chase Bank (formerly known as The Chase Manhattan Bank), as Trustee
(the "Trustee," which term includes any successor trustee under the Senior
Indenture) (as may be amended or supplemented from time to time, the "Senior
Indenture"), to which Senior Indenture and all indentures supplemental thereto
reference is hereby made for a statement of the respective rights, limitations
of rights, duties and immunities of the Issuer, the Trustee and holders of the
Notes and the terms upon which the Notes are, and are to be, authenticated and
delivered. The Issuer has appointed JPMorgan Chase Bank at its corporate trust
office in The City of New York as the paying agent (the "Paying Agent," which
term includes any additional or successor Paying Agent appointed by the Issuer)
with respect to the Notes. The terms of individual Notes may vary with respect
to interest rates, interest rate formulas, issue dates, maturity dates, or
otherwise, all as provided in the Senior Indenture. To the extent not
inconsistent herewith, the terms of the Senior Indenture are hereby
incorporated by reference herein.

     Unless otherwise indicated on the face hereof, this Note shall not be
subject to any sinking fund and, unless otherwise provided on the face hereof
in accordance with the provisions of the following two paragraphs, shall not be
redeemable or subject to repayment at the option of the holder prior to
maturity.

     If so indicated on the face of hereof, this Note may be redeemed in whole
or in part at the option of the Issuer on or after the Initial Redemption Date
specified on the face hereof on the terms set forth on the face hereof,
together with interest accrued and unpaid hereon to the date of redemption. If
this Note is subject to "Annual Redemption Percentage Reduction," the Initial
Redemption Percentage indicated on the face hereof shall be reduced on each
anniversary of the Initial Redemption Date by the Annual Redemption Percentage
Reduction specified on the face hereof until the redemption price of this Note
is 100% of the principal amount hereof, together with interest accrued and
unpaid hereon to the date of redemption. Notice of redemption shall be mailed
to the registered holders of the Notes designated for redemption at their
addresses as the same shall appear on the Note register not less than 30 nor
more than 60 calendar days prior to the date fixed for redemption or within the
Redemption Notice Period specified on the face hereof, subject to all the
conditions and provisions of the Senior Indenture. In the event of redemption
of this Note in part only, a new Note or Notes for the amount of the unredeemed
portion hereof shall be issued in the name of the holder hereof upon the
cancellation hereof.

     If so indicated on the face of hereof, this Note shall be subject to
repayment at the option of the holder on the Optional Repayment Date or Dates
specified on the face hereof on the terms set forth herein. On any Optional
Repayment Date, this Note shall be repayable in whole or in part in increments
of $1,000 or, if this Note is denominated in a Specified Currency other than
U.S. dollars, in increments of 1,000 units of such Specified Currency (provided
that any remaining principal amount hereof shall not be less than the minimum
authorized denomination hereof) at the option of the holder hereof at a price
equal to 100% of the principal amount to be repaid, together with interest
accrued and unpaid hereon to the date of repayment, provided that this Note is
issued with original

                                     A-20
<PAGE>

issue discount, this Note shall be repayable on the applicable Optional
Repayment Date or Dates at the price(s) specified on the face hereof. For this
Note to be repaid at the option of the holder hereof, the Paying Agent must
receive at its corporate trust office in the Borough of Manhattan, The City of
New York, at least 15 but not more than 30 calendar days prior to the date of
repayment, (i) this Note with the form entitled "Option to Elect Repayment"
below duly completed or (ii) a telegram, telex, facsimile transmission or a
letter from a member of a national securities exchange or the National
Association of Securities Dealers, Inc. or a commercial bank or a trust company
in the United States setting forth the name of the holder of this Note, the
principal amount hereof, the certificate number of this Note or a description
of this Note's tenor and terms, the principal amount hereof to be repaid, a
statement that the option to elect repayment is being exercised thereby and a
guarantee that this Note, together with the form entitled "Option to Elect
Repayment" duly completed, shall be received by the Paying Agent not later than
the fifth Business Day after the date of such telegram, telex, facsimile
transmission or letter; provided, that such telegram, telex, facsimile
transmission or letter shall only be effective if this Note and form duly
completed are received by the Paying Agent by such fifth Business Day. Exercise
of such repayment option by the holder hereof shall be irrevocable. In the
event of repayment of this Note in part only, a new Note or Notes for the
amount of the unpaid portion hereof shall be issued in the name of the holder
hereof upon the cancellation hereof.

     Interest payments on this Note shall include interest accrued to but
excluding the Interest Payment Dates or the Maturity Date (or any earlier
redemption or repayment date), as the case may be. Unless otherwise provided on
the face hereof, interest payments for this Note shall be computed and paid on
the basis of a 360 day year of twelve 30 day months.

     In the case where the Interest Payment Date or the Maturity Date (or any
redemption or repayment date) does not fall on a Business Day, payment of
interest, premium, if any, or principal otherwise payable on such date need not
be made on such date, but may be made on the next succeeding Business Day with
the same force and effect as if made on the Interest Payment Date or on the
Maturity Date (or any redemption or repayment date), and no interest on such
payment shall accrue for the period from and after the Interest Payment Date or
the Maturity Date (or any redemption or repayment date) to such next succeeding
Business Day.

     This Note and all the obligations of the Issuer hereunder are direct,
unsecured obligations of the Issuer and rank without preference or priority
among themselves and pari passu with all other existing and future unsecured
and unsubordinated indebtedness of the Issuer, subject to certain statutory
exceptions in the event of liquidation upon insolvency.

     This Note, and any Note or Notes issued upon transfer or exchange hereof,
is issuable only in fully registered form, without coupons, and, if denominated
in U.S. dollars, unless otherwise stated above, is issuable only in
denominations of U.S. $1,000 and any integral multiple of U.S. $1,000 in excess
thereof. If this Note is denominated in a Specified Currency other than U.S.
dollars, then, unless a higher minimum denomination is required by applicable
law, it is issuable only in denominations of the equivalent of U.S. $1,000
(rounded to an integral multiple of 1,000 units of such Specified Currency), or
any amount in excess thereof which is an integral multiple of 1,000 units of
such Specified Currency, as determined by reference to the noon dollar buying
rate in The City of New York for cable transfers of such Specified Currency
published by the Federal

                                     A-21
<PAGE>

Reserve Bank of New York (the "Market Exchange Rate") on the Business Day
immediately preceding the date of issuance.

     The Trustee has been appointed registrar for the Notes, and the Trustee
shall maintain at its office in The City of New York a register for the
registration and transfer of Notes. This Note may be transferred at the
aforesaid office of the Trustee by surrendering this Note for cancellation,
accompanied by a written instrument of transfer in form satisfactory to the
Issuer and the Trustee and duly executed by the registered holder hereof in
person or by the holder's attorney duly authorized in writing, and thereupon
the Trustee shall issue in the name of the transferee or transferees, in
exchange herefor, a new Note or Notes having identical terms and provisions and
having a like aggregate principal amount in authorized denominations, subject
to the terms and conditions set forth herein; provided, however, that the
Trustee shall not be required (i) to register the transfer of or exchange any
Note that has been called for redemption in whole or in part, except the
unredeemed portion of Notes being redeemed in part, (ii) to register the
transfer of or exchange any Note if the holder thereof has exercised his right,
if any, to require the Issuer to repurchase such Note in whole or in part,
except the portion of such Note not required to be repurchased, or (iii) to
register the transfer of or exchange Notes to the extent and during the period
so provided in the Senior Indenture with respect to the redemption of Notes.
Notes are exchangeable at said office for other Notes of other authorized
denominations of equal aggregate principal amount having identical terms and
provisions. All such exchanges and transfers of Notes shall be free of charge,
but the Issuer may require payment of a sum sufficient to cover any tax or
other governmental charge in connection therewith. All Notes surrendered for
exchange shall be accompanied by a written instrument of transfer in form
satisfactory to the Issuer and the Trustee and executed by the registered
holder in person or by the holder's attorney duly authorized in writing. The
date of registration of any Note delivered upon any exchange or transfer of
Notes shall be such that no gain or loss of interest results from such exchange
or transfer.

     In case this Note shall at any time become mutilated, defaced or be
destroyed, lost or stolen and this Note or evidence of the loss, theft or
destruction thereof (together with the indemnity hereinafter referred to and
such other documents or proof as may be required in the premises) shall be
delivered to the Trustee, the Issuer in its discretion may execute a new Note
of like tenor in exchange for this Note, but, if this Note is destroyed, lost
or stolen, only upon receipt of evidence satisfactory to the Trustee and the
Issuer that this Note was destroyed or lost or stolen and, if required, upon
receipt also of indemnity satisfactory to each of them. All expenses and
reasonable charges associated with procuring such indemnity and with the
preparation, authentication and delivery of a new Note shall be borne by the
owner of the Note mutilated, defaced, destroyed, lost or stolen.

     The Senior Indenture provides that (a) if an Event of Default (as defined
in the Senior Indenture) due to the default in payment of principal of,
premium, if any, or interest on, any series of debt securities issued under the
Senior Indenture, including the series of Senior Medium-Term Notes of which
this Note forms a part, or due to the default in the performance or breach of
any other covenant or warranty of the Issuer applicable to the debt securities
of such series but not applicable to all outstanding debt securities issued
under the Senior Indenture shall have occurred and be continuing, either the
Trustee or the holders of not less than 25% in aggregate principal amount of
the outstanding debt securities of each affected series, voting as one class,
by notice in writing to the Issuer and to the Trustee, if given by the
securityholders, may then declare the

                                     A-22
<PAGE>

principal of all debt securities of all such series and interest accrued
thereon to be due and payable immediately and (b) if an Event of Default due to
a default in the performance of any other of the covenants or agreements in the
Senior Indenture applicable to all outstanding debt securities issued
thereunder, including this Note, or due to certain events of bankruptcy,
insolvency or reorganization of the Issuer, shall have occurred and be
continuing, either the Trustee or the holders of not less than 25% in aggregate
principal amount of all outstanding debt securities issued under the Senior
Indenture, voting as one class, by notice in writing to the Issuer and to the
Trustee, if given by the securityholders, may declare the principal of all such
debt securities and interest accrued thereon to be due and payable immediately,
but upon certain conditions such declarations may be annulled and past defaults
may be waived (except a continuing default in payment of principal or premium,
if any, or interest on such debt securities) by the holders of a majority in
aggregate principal amount of the debt securities of all affected series then
outstanding.

     If the face hereof indicates that this Note is subject to "Modified
Payment upon Acceleration and Redemption," then (i) if the principal hereof is
declared to be due and payable as described in the preceding paragraph, the
amount of principal due and payable with respect to this Note shall be limited
to the aggregate principal amount hereof multiplied by the sum of the Issue
Price specified on the face hereof (expressed as a percentage of the aggregate
principal amount) plus the original issue discount amortized from the Interest
Accrual Date to the date of declaration, which amortization shall be calculated
using the "interest method" (computed in accordance with generally accepted
accounting principles in effect on the date of declaration), (ii) for the
purpose of any vote of securityholders taken pursuant to the Senior Indenture
prior to the acceleration of payment of this Note, the principal amount hereof
shall equal the amount that would be due and payable hereon, calculated as set
forth in clause (i) above, if this Note were declared to be due and payable on
the date of any such vote and (iii) for the purpose of any vote of
securityholders taken pursuant to the Senior Indenture following the
acceleration of payment of this Note, the principal amount hereof shall equal
the amount of principal due and payable with respect to this Note, calculated
as set forth in clause (i) above.

     If the face hereof indicates that this Note is subject to "Tax Redemption
and Payment of Additional Amounts," this Note may be redeemed, as a whole, at
the option of the Issuer at any time prior to maturity, upon the giving of a
notice of redemption as described below, at a redemption price equal to 100% of
the principal amount hereof, together with accrued interest to the date fixed
for redemption (except that if this Note is subject to "Modified Payment upon
Acceleration or Redemption," such redemption price would be limited to the
aggregate principal amount hereof multiplied by the sum of the Issue Price
specified on the face hereof (expressed as a percentage of the aggregate
principal amount) plus the original issue discount amortized from the Interest
Accrual Date to the date of redemption, which amortization shall be calculated
using the "interest method" (computed in accordance with generally accepted
accounting principles in effect on the date of redemption) (the "Amortized
Amount")), if the Issuer determines that, as a result of any change in or
amendment to the laws, or any regulations or rulings promulgated thereunder, of
the United States or of any political subdivision or taxing authority thereof
or therein affecting taxation, or any change in official position regarding the
application or interpretation of such laws, regulations or rulings, which
change or amendment becomes effective on or after the Initial Offering Date
hereof, the Issuer has or shall become obligated to pay Additional Amounts, as
defined below, with respect to this Note as described below. Prior to the
giving of any notice of redemption pursuant to this paragraph, the Issuer shall
deliver to the Trustee (i) a certificate stating that the Issuer is entitled to
effect such

                                     A-23
<PAGE>

redemption and setting forth a statement of facts showing that the conditions
precedent to the right of the Issuer to so redeem have occurred, and (ii) an
opinion of independent legal counsel satisfactory to the Trustee to such effect
based on such statement of facts; provided that no such notice of redemption
shall be given earlier than 60 calendar days prior to the earliest date on
which the Issuer would be obligated to pay such Additional Amounts if a payment
in respect of this Note were then due.

     Notice of redemption shall be given not less than 30 nor more than 60
calendar days prior to the date fixed for redemption or within the Redemption
Notice Period specified on the face hereof, which date and the applicable
redemption price shall be specified in the notice.

     If the face hereof indicates that this Note is subject to "Tax Redemption
and Payment of Additional Amounts," the Issuer shall, subject to certain
exceptions and limitations set forth below, pay such additional amounts (the
"Additional Amounts") to the holder of this Note who is a United States Alien
as may be necessary in order that every net payment of the principal of and
interest on this Note and any other amounts payable on this Note, after
withholding or deduction for or on account of any present or future tax,
assessment or governmental charge imposed upon or as a result of such payment
by the United States, or any political subdivision or taxing authority thereof
or therein, shall not be less than the amount provided for in this Note to be
then due and payable. The Issuer shall not, however, be required to make any
payment of Additional Amounts to any such holder who is a United States Alien
for or on account of:

          (a) any present or future tax, assessment or other governmental
     charge that would not have been so imposed but for (i) the existence of
     any present or former connection between such holder, or between a
     fiduciary, settlor, beneficiary, member or shareholder of such holder, if
     such holder is an estate, a trust, a partnership or a corporation for
     United States federal income tax purposes, and the United States,
     including, without limitation, such holder, or such fiduciary, settlor,
     beneficiary, member or shareholder, being or having been a citizen or
     resident thereof or being or having been engaged in a trade or business or
     present therein or having, or having had, a permanent establishment
     therein or (ii) the presentation by or on behalf the holder of this Note
     for payment on a date more than 15 calendar days after the date on which
     such payment became due and payable or the date on which payment thereof
     is duly provided for, whichever occurs later;

          (b) any estate, inheritance, gift, sales, transfer, excise or
     personal property tax or any similar tax, assessment or governmental
     charge;

          (c) any tax, assessment or other governmental charge imposed by
     reason of such holder's past or present status as a personal holding
     company or foreign personal holding company or controlled foreign
     corporation or passive foreign investment company with respect to the
     United States or as a corporation which accumulates earnings to avoid
     United States federal income tax or as a private foundation or other tax
     exempt organization or a bank receiving interest under Section
     881(c)(3)(A) of the Internal Revenue Code of 1986, as amended;

          (d) any tax, assessment or other governmental charge that is payable
     otherwise than by withholding or deduction from payments on or in respect
     of this Note;

                                     A-24
<PAGE>

          (e) any tax, assessment or other governmental charge required to be
     withheld by any Paying Agent from any payment of principal of, or interest
     on, this Note, if such payment can be made without such withholding by any
     other Paying Agent in a city in Western Europe;

          (f) any tax, assessment or other governmental charge that would not
     have been imposed but for the failure to comply with certification,
     information or other reporting requirements concerning the nationality,
     residence or identity of the holder or beneficial owner of this Note, if
     such compliance is required by statute or by regulation of the United
     States or of any political subdivision or taxing authority thereof or
     therein as a precondition to relief or exemption from such tax, assessment
     or other governmental charge;

          (g) any tax, assessment or other governmental charge imposed by
     reason of such holder's past or present status as the actual or
     constructive owner of 10% or more of the total combined voting power of
     all classes of stock entitled to vote of the Issuer or as a direct or
     indirect subsidiary of the Issuer; or

          (h) any combination of items (a), (b), (c), (d), (e), (f) or (g).

In addition, the Issuer shall not be required to make any payment of Additional
Amounts (i) to any such holder where such withholding or deduction is imposed
on a payment to an individual and is required to be made pursuant to any law
implementing or complying with, or introduced in order to conform to, any
European Union Directive on the taxation of savings; or (ii) by or on behalf of
a holder who would have been able to avoid such withholding or deduction by
presenting this Note or the relevant coupon to another Paying Agent in a member
state of the European Union. Nor shall the Issuer pay Additional Amounts with
respect to any payment on this Note to a United States Alien who is a fiduciary
or partnership or other than the sole beneficial owner of such payment to the
extent such payment would be required by the laws of the United States (or any
political subdivision thereof) to be included in the income, for tax purposes,
of a beneficiary or settlor with respect to such fiduciary or a member of such
partnership or a beneficial owner who would not have been entitled to the
Additional Amounts had such beneficiary, settlor, member or beneficial owner
been the holder of this Note.

     The Senior Indenture permits the Issuer and the Trustee, with the consent
of the holders of not less than a majority in aggregate principal amount of the
debt securities of all series issued under the Senior Indenture then
outstanding and affected (voting as one class), to execute supplemental
indentures adding any provisions to or changing in any manner the rights of the
holders of each series so affected; provided that the Issuer and the Trustee
may not, without the consent of the holder of each outstanding debt security
affected thereby, (a) extend the final maturity of any such debt security, or
reduce the principal amount thereof, or reduce the rate or extend the time of
payment of interest thereon, or reduce any amount payable on redemption
thereof, or change the currency of payment thereof, or modify or amend the
provisions for conversion of any currency into any other currency, or modify or
amend the provisions for conversion or exchange of the debt security for
securities of the Issuer or other entities or for other property or the cash
value of the property (other than as provided in the antidilution provisions or
other similar adjustment provisions of the debt securities or otherwise in
accordance with the terms thereof), or impair or affect the rights of any
holder to institute suit for the payment thereof or (b) reduce the aforesaid
percentage in principal

                                     A-25
<PAGE>

amount of debt securities the consent of the holders of which is required for
any such supplemental indenture.

     Except as set forth below, if the principal of, premium, if any, or
interest on this Note is payable in a Specified Currency other than U.S.
dollars and such Specified Currency is not available to the Issuer for making
payments hereon due to the imposition of exchange controls or other
circumstances beyond the control of the Issuer or is no longer used by the
government of the country issuing such currency or for the settlement of
transactions by public institutions within the international banking community,
then the Issuer shall be entitled to satisfy its obligations to the holder of
this Note by making such payments in U.S. dollars on the basis of the Market
Exchange Rate on the date of such payment or, if the Market Exchange Rate is
not available on such date, as of the most recent practicable date; provided,
however, that if the euro has been substituted for such Specified Currency, the
Issuer may at its option (or shall, if so required by applicable law) without
the consent of the holder of this Note effect the payment of principal of,
premium, if any, or interest on any Note denominated in such Specified Currency
in euro in lieu of such Specified Currency in conformity with legally
applicable measures taken pursuant to, or by virtue of, the Treaty establishing
the European Community, as amended. Any payment made under such circumstances
in U.S. dollars or euro where the required payment is in an unavailable
Specified Currency shall not constitute an Event of Default. If such Market
Exchange Rate is not then available to the Issuer or is not published for a
particular Specified Currency, the Market Exchange Rate shall be based on the
highest bid quotation in The City of New York received by the Exchange Rate
Agent at approximately 11:00 a.m., New York City time, on the second Business
Day preceding the date of such payment from three recognized foreign exchange
dealers (the "Exchange Dealers") for the purchase by the quoting Exchange
Dealer of the Specified Currency for U.S. dollars for settlement on the payment
date, in the aggregate amount of the Specified Currency payable to those
holders or beneficial owners of Notes and at which the applicable Exchange
Dealer commits to execute a contract. One of the Exchange Dealers providing
quotations may be the Exchange Rate Agent unless the Exchange Rate Agent is an
affiliate of the Issuer. If those bid quotations are not available, the
Exchange Rate Agent shall determine the market exchange rate at its sole
discretion.

     The "Exchange Rate Agent" shall be Morgan Stanley & Co. Incorporated,
unless otherwise indicated on the face hereof.

     All determinations referred to above made by, or on behalf of, the Issuer
or by, or on behalf of, the Exchange Rate Agent shall be at such entity's sole
discretion and shall, in the absence of manifest error, be conclusive for all
purposes and binding on holders of Notes and coupons.

     So long as this Note shall be outstanding, the Issuer shall cause to be
maintained an office or agency for the payment of the principal of and premium,
if any, and interest on this Note as herein provided in the Borough of
Manhattan, The City of New York, and an office or agency in said Borough of
Manhattan for the registration, transfer and exchange as aforesaid of the
Notes. The Issuer may designate other agencies for the payment of said
principal, premium and interest at such place or places (subject to applicable
laws and regulations) as the Issuer may decide. So long as there shall be such
an agency, the Issuer shall keep the Trustee advised of the names and locations
of such agencies, if any are so designated. If any European Union Directive on
the taxation of savings comes into force, the Issuer will, to the extent
possible as a matter of law, maintain a Paying Agent in a member state of the
European Union that shall not be obligated to withhold or deduct tax

                                     A-26
<PAGE>

pursuant to any such Directive or any law implementing or complying with, or
introduced in order to conform to, such Directive.

     With respect to moneys paid by the Issuer and held by the Trustee or any
Paying Agent for payment of the principal of or interest or premium, if any, on
any Notes that remain unclaimed at the end of two years after such principal,
interest or premium shall have become due and payable (whether at maturity or
upon call for redemption or otherwise), (i) the Trustee or such Paying Agent
shall notify the holders of such Notes that such moneys shall be repaid to the
Issuer and any person claiming such moneys shall thereafter look only to the
Issuer for payment thereof and (ii) such moneys shall be so repaid to the
Issuer. Upon such repayment all liability of the Trustee or such Paying Agent
with respect to such moneys shall thereupon cease, without, however, limiting
in any way any obligation that the Issuer may have to pay the principal of or
interest or premium, if any, on this Note as the same shall become due.

     No provision of this Note or of the Senior Indenture shall alter or impair
the obligation of the Issuer, which is absolute and unconditional, to pay the
principal of, premium, if any, and interest on this Note at the time, place,
and rate, and in the coin or currency, herein prescribed unless otherwise
agreed between the Issuer and the registered holder of this Note.

     Prior to due presentment of this Note for registration of transfer, the
Issuer, the Trustee and any agent of the Issuer or the Trustee may treat the
holder in whose name this Note is registered as the owner hereof for all
purposes, whether or not this Note be overdue, and none of the Issuer, the
Trustee or any such agent shall be affected by notice to the contrary.

     No recourse shall be had for the payment of the principal of, premium, if
any, or the interest on this Note, for any claim based hereon, or otherwise in
respect hereof, or based on or in respect of the Senior Indenture or any
indenture supplemental thereto, against any incorporator, shareholder, officer
or director, as such, past, present or future, of the Issuer or of any
successor corporation, either directly or through the Issuer or any successor
corporation, whether by virtue of any constitution, statute or rule of law or
by the enforcement of any assessment or penalty or otherwise, all such
liability being, by the acceptance hereof and as part of the consideration for
the issue hereof, expressly waived and released.

     This Note shall for all purposes be governed by, and construed in
accordance with, the laws of the State of New York.

     As used herein, the term "United States Alien" means any person who is,
for United States federal income tax purposes, (i) a nonresident alien
individual, (ii) a foreign corporation, (iii) a nonresident alien fiduciary of
a foreign estate or trust or (iv) a foreign partnership one or more of the
members of which is, for United States federal income tax purposes, a
nonresident alien individual, a foreign corporation or a nonresident alien
fiduciary of a foreign estate or trust.

     All terms used in this Note which are defined in the Senior Indenture and
not otherwise defined herein shall have the meanings assigned to them in the
Senior Indenture.

                                     A-27
<PAGE>

                                 ABBREVIATIONS

     The following abbreviations, when used in the inscription on the face of
this instrument, shall be construed as though they were written out in full
according to applicable laws or regulations:

         TEN COM    -   as tenants in common
         TEN ENT    -   as tenants by the entireties
         JT TEN     -   as joint tenants with right of survivorship
                        and not as tenants in common

    UNIF GIFT MIN ACT -                       Custodian
                       -----------------------         ------------------------
                              (Minor)                           (Cust)

    Under Uniform Gifts to Minors Act
                                     ----------------------------
                                              (State)

    Additional abbreviations may also be used though not in the above list.

                            -----------------------

                                     A-28
<PAGE>

     FOR VALUE RECEIVED, the undersigned hereby sell(s), assign(s) and
transfer(s) unto

---------------------------------------
[PLEASE INSERT SOCIAL SECURITY OR OTHER
   IDENTIFYING NUMBER OF ASSIGNEE]

-------------------------------------------------------------------------------

-------------------------------------------------------------------------------

-------------------------------------------------------------------------------
[PLEASE PRINT OR TYPE NAME AND ADDRESS, INCLUDING ZIP CODE, OF ASSIGNEE]

the within Note and all rights thereunder, hereby irrevocably constituting and
appointing such person attorney to transfer such note on the books of the
Issuer, with full power of substitution in the premises.

Dated:
      -----------------------

NOTICE:   The signature to this assignment must correspond with the name as
          written upon the face of the within Note in every particular without
          alteration or enlargement or any change whatsoever.

                                     A-29
<PAGE>

                           OPTION TO ELECT REPAYMENT

     The undersigned hereby irrevocably requests and instructs the Issuer to
repay the within Note (or portion thereof specified below) pursuant to its
terms at a price equal to the principal amount thereof, together with interest
to the Optional Repayment Date, to the undersigned at

-------------------------------------------------------------------------------

-------------------------------------------------------------------------------

-------------------------------------------------------------------------------
        (Please print or typewrite name and address of the undersigned)

     If less than the entire principal amount of the within Note is to be r
thereof which the holder elects to have repaid:________________; and specify
the denomination or denominations (which shall not be less than the minimum
authorized denomination) of the Notes to be issued to the holder for the
portion of the within Note not being repaid (in the absence of any such
specification, one such Note shall be issued for the portion not being
repaid):_________________.

Dated:
      ----------------------------     ----------------------------------------
                                       NOTICE:  The signature on this Option to
                                       Elect Repayment must correspond with
                                       the name as written upon the face of the
                                       within instrument in every particular
                                       without alteration or enlargement.

                                     A-30

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