Document:

exv4w1

 

Exhibit 4.1

     Unless this certificate is presented by an authorized representative of The Depository Trust
Company, a New York Corporation (“DTC”), to the Company or its agent for registration of transfer,
exchange, or payment, and any certificate issued is registered in the name of Cede & Co. or in such
other name as is requested by an authorized representative of DTC (and any payment is made to Cede
& Co. or to such other entity as is requested by an authorized representative of DTC), ANY
TRANSFER, PLEDGE, OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL
inasmuch as the registered owner hereof, Cede & Co., has an interest herein.

	 	 	 
	Certificate No.: 1

	 	CUSIP No.: 637432KT1
	 
	 	 
	ISIN No.:
	 	 
	 
	 	 
	PRINCIPAL AMOUNT: $500,000,000
	 	 
	 
	 	 
	MATURITY DATE: February 1, 2018
	 	 
	 
	 	 
	ISSUE DATE: January 23, 2008

	 	CERTIFICATE INTEREST RATE: 5.45%

5.45% COLLATERAL TRUST BOND DUE 2018

          National Rural Utilities Cooperative Finance Corporation, a District of Columbia cooperative
association (hereinafter called the “Company”, which term includes any successor corporation under
the Indenture referred to on the reverse hereof), for value received, hereby promises to pay to
Cede & Co., or registered assigns, the principal sum of $500,000,000 on the Maturity Date set forth
above; and to pay interest thereon from the Issue Date set forth above at the Certificate Interest
Rate set forth above, until the principal hereof is paid or made available for payment.

          Interest on the Bonds will be payable on February 1 and August 1 of each year commencing on
August 1, 2008 to the persons in whose names such Bonds are registered at the close of business on
the fifteenth calendar day preceding the payment date, or if not a Business Day, the next
succeeding Business Day. Interest on the Bonds will accrue from and including the date of issue or
from and including the last date in respect of which interest has been paid, as the case may be,
to, but excluding, the relevant interest payment date, date of redemption or the date

 

 

of maturity, as the case may be. Interest on the Bonds will be computed on the basis of a
360-day year of twelve 30-day months.

          If any of the interest payment dates or the maturity date falls on a day that is not a
Business Day, the payment of interest or principal will be postponed to the next succeeding
Business Day, but the payment made on such dates will be treated as being made on the date payment
was first due and the holders of the Bonds will not be entitled to any further interest or other
payments with respect to such postponements.

          Reference is hereby made to the further provisions of this Bond set forth on the reverse
hereof which further provisions shall for all purposes have the same effect as if set forth at this
place.

          Unless the certificate of authentication hereon has been executed by or on behalf of U.S. Bank
National Association, the Trustee under such Indenture, or its successor thereunder, by manual
signature, this Bond shall not be entitled to any benefit under such Indenture, or be valid or
obligatory for any purpose.

 

 

          IN WITNESS WHEREOF, the Company has caused this instrument to be duly executed under its
corporate seal.

	 	 	 	 	 	 	 
	 	 	NATIONAL RURAL UTILITIES	 	 
	 	 	COOPERATIVE FINANCE CORPORATION	 	 
	 
	 	 	 	 	 	 
	 

	 	By:	 	 	 	 
	 

	 	 	 	 

John J. List
	 	 
	 

	 	 	 	Senior Vice President	 	 
	 

	 	 	 	Assistant Secretary-Treasurer	 	 

(Seal)

Attest:

	 	 	 	 	 
	By:
	 	 	 	 
	 

	 	 	 	 
	 

	 	Assistant Secretary-Treasurer	 	 
	 
	 	 	 	 
	Trustee’s Certificate of Authentication	 	 
	This is one of the Bonds	 	 
	of the series designated therein,	 	 
	described in the within-	 	 
	mentioned Indenture	 	 
	 
	 	 	 	 
	Dated:	 	 
	 
	 	 	 	 
	By:

	 	U.S. BANK NATIONAL ASSOCIATION,	 	 
	 

	 	     Trustee	 	 
	 
	 	 	 	 
	By:
	 	 	 	 
	 

	 	 

     Authorized Officer
	 	 

 

 

REVERSE OF BOND

          This Bond is one of an authorized issue of Bonds of the Company known as its “5.45% Collateral
Trust Bonds due 2018”, issued and to be issued in one or more series under, and all equally and
ratably secured (except as any sinking or other fund may afford additional special security for the
Bonds of any particular series) by, an Indenture dated as of October 25, 2007 (as amended,
supplemented and modified and in effect from time to time, the “Indenture”), executed by the
Company to U.S. Bank National Association, as Trustee (herein called the “Trustee”, which term
includes any successor Trustee under the Indenture), to which Indenture reference is hereby made
for a description of the nature and extent of the securities and other property assigned, pledged,
transferred and mortgaged thereunder, the rights of the Holders of said Bonds and of the Trustee
and of the Company in respect of such security, and the terms upon which said Bonds are to be
authenticated and delivered.

          The Indenture permits, with certain exceptions as therein provided, the amendment thereof and
the modification of the rights and obligations of the Company and the rights of the Holders of the
Bonds under the Indenture at any time by the Company with the consent of the Holders of not less
than a majority in aggregate principal amount of the Bonds at the time Outstanding (as defined in
the Indenture). The Indenture also permits, without the consent of the holders of any Bonds, the
parties to any Mortgage Notes pledged under the Indenture, and any Mortgages or Loan Agreements
pursuant to which they were issued, to modify, alter, supplement or amend such Mortgage Notes,
Mortgages and Loan Agreements, so long as thereafter such Mortgage will comply with the
requirements of the Company’s standard lending practices, as such policies may be amended from time
to time. The Indenture also contains provisions permitting the Holders of specified percentages in
principal amount of the Bonds at the time Outstanding, on behalf of the Holders of all Bonds, to
waive compliance by

 

 

the Company with certain provisions of the Indenture and certain past defaults under the
Indenture and their consequences. Any such consent or waiver by the Holder of this Bond shall be
binding upon such Holder and upon all future Holders of this Bond and of any Bond issued upon the
transfer hereof or in exchange herefor or in lieu hereof whether or not notation of such action is
made upon this Bond.

          As provided in the Indenture, said Bonds are issuable in series which may vary as in said
Indenture provided or permitted. This Bond is one of a series entitled 5.45% Collateral Trust
Bonds due 2018.

          The Company may redeem the Bonds in whole or in part at any time, at a “make-whole” redemption
price equal to the greater of (1) the principal amount being redeemed or (2) the sum of the present
values of the remaining scheduled payments of the principal and interest (other than accrued
interest) on the Bonds being redeemed, discounted to the redemption date on a semi-annual basis
(assuming a 360-day year consisting of twelve 30-day months) at the Treasury Rate plus 25 basis
points for the Bonds, plus in each case accrued interest to the redemption date.

          If the Company elects to redeem less than all of the Bonds, and such Bonds are at the time
represented by a global security, then the depositary will select by lot the particular interest to
be redeemed. If the Company elects to redeem less than all of the Bonds, and such Bonds are not
represented by a global security, the particular Bonds to be redeemed shall be selected by the
Trustee from the outstanding Bonds not previously called for redemption, in a manner the Trustee
deems appropriate and fair.

          Notice of any redemption will be mailed at least 30 days but not more than 60 days before the
date of redemption to each holder of the Bonds to be redeemed. Unless the Company defaults in
payment of the redemption price, on and after the date of redemption,

 

 

interest will cease to accrue on such Bonds or the portions called for redemption.

          If an Event of Default, as defined in the Indenture, shall occur, the principal of this Bond
may become or be declared due and payable immediately, in the manner and with the effect provided
in the Indenture.

          This Bond is transferable by the registered owner hereof in person or by attorney authorized
in writing at the office or agency of the Company in the Borough of Manhattan, City and State of
New York or any other place or places where such Bond may be paid, upon surrender of this Bond, and
upon any such transfer a new Bond for the same series, for the same aggregate principal amount,
will be issued to the transferee in exchange hereof.

          The Bonds of this series are issuable only as registered Bonds without coupons in minimum
denominations of $2,000 and integral multiples of $1,000 in excess thereof. As provided in, and
subject to the provisions of, the Indenture, Bonds of this series are exchangeable for other Bonds
of this series of any authorized denominations, of a like aggregate principal amount, as requested
by the Holder surrendering the same.

          No service charge will be made for any such transfer or exchange, but the Company or the
Trustee may require payment of a sum sufficient to cover any tax or other governmental charge
payable in connection therewith.

          Prior to due presentment for transfer at any office or agency of the Company designated for
such purpose, the Company, the Trustee and any agent of the Company or the Trustee may treat the
person in whose name this Bond is registered as the owner hereof for the purpose of receiving
payment as herein provided and for all other purposes whether or not this Bond be overdue, and
neither the Company, the Trustee nor any such agent shall be affected by notice to the contrary.

 

 

          No reference herein to the Indenture and no provision of this Bond or of the Indenture shall
alter or impair the obligation of the Company, which is absolute and unconditional, to pay the
principal of, and interest on this Bond at the times, place and rate, and in the coin or currency,
herein prescribed.

          The following terms shall have the following meanings:

          “Business Day” means each Monday, Tuesday, Wednesday, Thursday and Friday which is not a day
on which banking institutions in the Borough of Manhattan, City and State of New York are
authorized by law to close.

          “Comparable Treasury Issue” means the United States Treasury security selected by an
Independent Investment Banker as having a maturity comparable to the remaining term of the Bonds
being redeemed that would be utilized, at the time of selection and in accordance with customary
financial practice, in pricing new issues of corporate debt securities of comparable maturity to
the remaining term of such Bonds.

          “Comparable Treasury Price” means, for any redemption date, (1) the average of the bid and ask
prices for the Comparable Treasury Issue (expressed in each case as a percentage of its principal
amount) on the third business day preceding the redemption date, as set forth in the daily
statistical release (or any successor release) published by the Federal Reserve Bank of New York
and designated “Composite 3:30 p.m. Quotations for U.S. Government Securities” or (2) if that
release (or any successor release) is not published or does not contain those prices on that
Business Day, (A) the average of the Reference Treasury Dealer Quotations for the redemption date,
after excluding the highest and lowest Reference Treasury Dealer Quotations for that redemption
date, or (B) if the Company obtains fewer than four Reference Treasury Dealer Quotations, the
average of all the Reference Treasury Dealer Quotations obtained.

 

 

          “Independent Investment Banker” means one of the Reference Treasury Dealers appointed by the
trustee after consultation with the Company.

          “Reference Treasury Dealer” means (1) each of Deutsche Bank Securities Inc., Lehman Brothers
Inc., and Greenwich Capital Markets, Inc. and their respective successors; provided, however, that
if any of them ceases to be a primary U.S. Government securities dealer in the United States, the
Company will appoint another primary U.S. Government securities dealer as a substitute and (2) any
other U.S. Government securities dealers selected by the Company.

          “Reference Treasury Dealer Quotations” means, for each Reference Treasury Dealer and any
redemption date, the average, as determined by the trustee, of the bid and ask prices for the
Comparable Treasury Issue (expressed in each case as a percentage of its principal amount) quoted
in writing to the Trustee by the Reference Treasury Dealer at 5:00 p.m. New York City time on the
third business day preceding the redemption date for the bonds being redeemed.

          “Treasury Rate” means, for any redemption date, the rate per annum equal to the semi-annual
equivalent yield to maturity of the Comparable Treasury Issue, assuming a price for the Comparable
Treasury Issue (expressed as a percentage of its principal amount) equal to the Comparable Treasury
Price for the redemption date.

          All terms used in this Bond which are defined in the Indenture shall have the meanings
assigned to them in the Indenture.

 

 

ASSIGNMENT

          For value received the undersigned sells, assigns and transfers unto (name, address including
zip code and taxpayer I.D. or Social Security number of assignee)                                                            
                                                                               
 
                                                                               
  
                   
the within Certificate and does hereby
irrevocably constitute and appoint                                                                          
                                                                              
     
                        

          attorney to transfer the said Certificate on the books kept for
registration thereof with full power of substitution on the premises.

Dated:                                         

	 	 	 	 	 
	 

	 	 

Signature by or on behalf of Assignor
	 	 

 

 

     Unless this certificate is presented by an authorized representative of The Depository Trust
Company, a New York Corporation (“DTC”), to the Company or its agent for registration of transfer,
exchange, or payment, and any certificate issued is registered in the name of Cede & Co. or in such
other name as is requested by an authorized representative of DTC (and any payment is made to Cede
& Co. or to such other entity as is requested by an authorized representative of DTC), ANY
TRANSFER, PLEDGE, OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL
inasmuch as the registered owner hereof, Cede & Co., has an interest herein.

	 	 	 
	Certificate No.: 2

	 	CUSIP No.: 637432KT1
	 
	 	 
	ISIN No.:
	 	 
	 
	 	 
	PRINCIPAL AMOUNT: $200,000,000
	 	 
	 
	 	 
	MATURITY DATE: February 1, 2018
	 	 
	 
	 	 
	ISSUE DATE: January 23, 2008

	 	CERTIFICATE INTEREST RATE: 5.45%

5.45% COLLATERAL TRUST BOND DUE 2018

          National Rural Utilities Cooperative Finance Corporation, a District of Columbia cooperative
association (hereinafter called the “Company”, which term includes any successor corporation under
the Indenture referred to on the reverse hereof), for value received, hereby promises to pay to
Cede & Co., or registered assigns, the principal sum of $200,000,000 on the Maturity Date set forth
above; and to pay interest thereon from the Issue Date set forth above at the Certificate Interest
Rate set forth above, until the principal hereof is paid or made available for payment.

          Interest on the Bonds will be payable on February 1 and August 1 of each year commencing on
August 1, 2008 to the persons in whose names such Bonds are registered at the close of business on
the fifteenth calendar day preceding the payment date, or if not a Business Day, the next
succeeding Business Day. Interest on the Bonds will accrue from and including the date of issue or
from and including the last date in respect of which interest has been paid, as the case may be,
to, but excluding, the relevant interest payment date, date of redemption or the date

 

 

of maturity, as the case may be. Interest on the Bonds will be computed on the basis of a
360-day year of twelve 30-day months.

          If any of the interest payment dates or the maturity date falls on a day that is not a
Business Day, the payment of interest or principal will be postponed to the next succeeding
Business Day, but the payment made on such dates will be treated as being made on the date payment
was first due and the holders of the Bonds will not be entitled to any further interest or other
payments with respect to such postponements.

          Reference is hereby made to the further provisions of this Bond set forth on the reverse
hereof which further provisions shall for all purposes have the same effect as if set forth at this
place.

          Unless the certificate of authentication hereon has been executed by or on behalf of U.S. Bank
National Association, the Trustee under such Indenture, or its successor thereunder, by manual
signature, this Bond shall not be entitled to any benefit under such Indenture, or be valid or
obligatory for any purpose.

 

 

          IN WITNESS WHEREOF, the Company has caused this instrument to be duly executed under its
corporate seal.

	 	 	 	 	 	 	 
	 	 	NATIONAL RURAL UTILITIES	 	 
	 	 	COOPERATIVE FINANCE CORPORATION	 	 
	 
	 	 	 	 	 	 
	 

	 	By:	 	 	 	 
	 

	 	 	 	 

John J. List
	 	 
	 

	 	 	 	Senior Vice President	 	 
	 

	 	 	 	Assistant Secretary-Treasurer	 	 

(Seal)

Attest:

	 	 	 	 	 
	By:
	 	 	 	 
	 

	 	 

Assistant Secretary-Treasurer
	 	 
	 
	 	 	 	 
	Trustee’s Certificate of Authentication	 	 
	This is one of the Bonds	 	 
	of the series designated therein,	 	 
	described in the within-	 	 
	mentioned Indenture	 	 
	 
	 	 	 	 
	Dated:	 	 
	 
	 	 	 	 
	By:

	 	U.S. BANK NATIONAL ASSOCIATION,	 	 
	 

	 	     Trustee	 	 
	 
	 	 	 	 
	By:
	 	 	 	 
	 

	 	 	 	 
	 

	 	     Authorized Officer	 	 

 

 

REVERSE OF BOND

          This Bond is one of an authorized issue of Bonds of the Company known as its “5.45% Collateral
Trust Bonds due 2018”, issued and to be issued in one or more series under, and all equally and
ratably secured (except as any sinking or other fund may afford additional special security for the
Bonds of any particular series) by, an Indenture dated as of October 25, 2007 (as amended,
supplemented and modified and in effect from time to time, the “Indenture”), executed by the
Company to U.S. Bank National Association, as Trustee (herein called the “Trustee”, which term
includes any successor Trustee under the Indenture), to which Indenture reference is hereby made
for a description of the nature and extent of the securities and other property assigned, pledged,
transferred and mortgaged thereunder, the rights of the Holders of said Bonds and of the Trustee
and of the Company in respect of such security, and the terms upon which said Bonds are to be
authenticated and delivered.

          The Indenture permits, with certain exceptions as therein provided, the amendment thereof and
the modification of the rights and obligations of the Company and the rights of the Holders of the
Bonds under the Indenture at any time by the Company with the consent of the Holders of not less
than a majority in aggregate principal amount of the Bonds at the time Outstanding (as defined in
the Indenture). The Indenture also permits, without the consent of the holders of any Bonds, the
parties to any Mortgage Notes pledged under the Indenture, and any Mortgages or Loan Agreements
pursuant to which they were issued, to modify, alter, supplement or amend such Mortgage Notes,
Mortgages and Loan Agreements, so long as thereafter such Mortgage will comply with the
requirements of the Company’s standard lending practices, as such policies may be amended from time
to time. The Indenture also contains provisions permitting the Holders of specified percentages in
principal amount of the Bonds at the time Outstanding, on behalf of the Holders of all Bonds, to
waive compliance by

 

 

the Company with certain provisions of the Indenture and certain past defaults under the
Indenture and their consequences. Any such consent or waiver by the Holder of this Bond shall be
binding upon such Holder and upon all future Holders of this Bond and of any Bond issued upon the
transfer hereof or in exchange herefor or in lieu hereof whether or not notation of such action is
made upon this Bond.

          As provided in the Indenture, said Bonds are issuable in series which may vary as in said
Indenture provided or permitted. This Bond is one of a series entitled 5.45% Collateral Trust
Bonds due 2018.

          The Company may redeem the Bonds in whole or in part at any time, at a “make-whole” redemption
price equal to the greater of (1) the principal amount being redeemed or (2) the sum of the present
values of the remaining scheduled payments of the principal and interest (other than accrued
interest) on the Bonds being redeemed, discounted to the redemption date on a semi-annual basis
(assuming a 360-day year consisting of twelve 30-day months) at the Treasury Rate plus 25 basis
points for the Bonds, plus in each case accrued interest to the redemption date.

          If the Company elects to redeem less than all of the Bonds, and such Bonds are at the time
represented by a global security, then the depositary will select by lot the particular interest to
be redeemed. If the Company elects to redeem less than all of the Bonds, and such Bonds are not
represented by a global security, the particular Bonds to be redeemed shall be selected by the
Trustee from the outstanding Bonds not previously called for redemption, in a manner the Trustee
deems appropriate and fair.

          Notice of any redemption will be mailed at least 30 days but not more than 60 days before the
date of redemption to each holder of the Bonds to be redeemed. Unless the

 

 

Company defaults in payment of the redemption price, on and after the date of redemption, interest
will cease to accrue on such Bonds or the portions called for redemption.

          If an Event of Default, as defined in the Indenture, shall occur, the principal of this Bond
may become or be declared due and payable immediately, in the manner and with the effect provided
in the Indenture.

          This Bond is transferable by the registered owner hereof in person or by attorney authorized
in writing at the office or agency of the Company in the Borough of Manhattan, City and State of
New York or any other place or places where such Bond may be paid, upon surrender of this Bond, and
upon any such transfer a new Bond for the same series, for the same aggregate principal amount,
will be issued to the transferee in exchange hereof.

          The Bonds of this series are issuable only as registered Bonds without coupons in minimum
denominations of $2,000 and integral multiples of $1,000 in excess thereof. As provided in, and
subject to the provisions of, the Indenture, Bonds of this series are exchangeable for other Bonds
of this series of any authorized denominations, of a like aggregate principal amount, as requested
by the Holder surrendering the same.

          No service charge will be made for any such transfer or exchange, but the Company or the
Trustee may require payment of a sum sufficient to cover any tax or other governmental charge
payable in connection therewith.

          Prior to due presentment for transfer at any office or agency of the Company designated for
such purpose, the Company, the Trustee and any agent of the Company or the Trustee may treat the
person in whose name this Bond is registered as the owner hereof for the purpose of receiving
payment as herein provided and for all other purposes whether or not this

 

 

Bond be overdue, and neither the Company, the Trustee nor any such agent shall be affected by
notice to the contrary.

          No reference herein to the Indenture and no provision of this Bond or of the Indenture shall
alter or impair the obligation of the Company, which is absolute and unconditional, to pay the
principal of, and interest on this Bond at the times, place and rate, and in the coin or currency,
herein prescribed.

          The following terms shall have the following meanings:

          “Business Day” means each Monday, Tuesday, Wednesday, Thursday and Friday which is not a day
on which banking institutions in the Borough of Manhattan, City and State of New York are
authorized by law to close.

          “Comparable Treasury Issue” means the United States Treasury security selected by an
Independent Investment Banker as having a maturity comparable to the remaining term of the Bonds
being redeemed that would be utilized, at the time of selection and in accordance with customary
financial practice, in pricing new issues of corporate debt securities of comparable maturity to
the remaining term of such Bonds.

          “Comparable Treasury Price” means, for any redemption date, (1) the average of the bid and ask
prices for the Comparable Treasury Issue (expressed in each case as a percentage of its principal
amount) on the third business day preceding the redemption date, as set forth in the daily
statistical release (or any successor release) published by the Federal Reserve Bank of New York
and designated “Composite 3:30 p.m. Quotations for U.S. Government Securities” or (2) if that
release (or any successor release) is not published or does not contain those prices on that
Business Day, (A) the average of the Reference Treasury Dealer Quotations for the redemption date,
after excluding the highest and lowest Reference Treasury Dealer Quotations

 

 

for that redemption date, or (B) if the Company obtains fewer than four Reference Treasury
Dealer Quotations, the average of all the Reference Treasury Dealer Quotations obtained.

          “Independent Investment Banker” means one of the Reference Treasury Dealers appointed by the
trustee after consultation with the Company.

          “Reference Treasury Dealer” means (1) each of Deutsche Bank Securities Inc., Lehman Brothers
Inc., and Greenwich Capital Markets, Inc. and their respective successors; provided, however, that
if any of them ceases to be a primary U.S. Government securities dealer in the United States, the
Company will appoint another primary U.S. Government securities dealer as a substitute and (2) any
other U.S. Government securities dealers selected by the Company.

          “Reference Treasury Dealer Quotations” means, for each Reference Treasury Dealer and any
redemption date, the average, as determined by the trustee, of the bid and ask prices for the
Comparable Treasury Issue (expressed in each case as a percentage of its principal amount) quoted
in writing to the Trustee by the Reference Treasury Dealer at 5:00 p.m. New York City time on the
third business day preceding the redemption date for the bonds being redeemed.

          “Treasury Rate” means, for any redemption date, the rate per annum equal to the semi-annual
equivalent yield to maturity of the Comparable Treasury Issue, assuming a price for the Comparable
Treasury Issue (expressed as a percentage of its principal amount) equal to the Comparable Treasury
Price for the redemption date.

          All terms used in this Bond which are defined in the Indenture shall have the meanings
assigned to them in the Indenture.

 

 

ASSIGNMENT

          For value received the undersigned sells, assigns and transfers unto (name, address including
zip code and taxpayer I.D. or Social Security number of assignee)
                                                                               
                                                                                 
                                        
the within Certificate and does hereby
irrevocably constitute and appoint                                                                         
                                                                   
attorney to transfer the said Certificate on the books kept for
registration thereof with full power of substitution on the premises.

Dated:                                         

	 	 	 	 	 
	 

	 	 

Signature by or on behalf of Assignorexv10w1

 

Exhibit 10.1

PHARMION CORPORATION

INCENTIVE BONUS AND RETENTION PLAN

Effective as of January 21, 2008

     1. Introduction and Purpose

     This Pharmion Corporation Incentive Bonus and Retention Plan (the “Plan”) has been
adopted in connection with the transactions contemplated under that certain Agreement and Plan of
Merger, dated November 18, 2007 (the “Transactions”), pursuant to which Pharmion
Corporation (the “Company”) will become a wholly-owned subsidiary of Celgene Corporation
(“Celgene”). Both the Company and Celgene believe that the value of the Company will be
enhanced by the continued employment of the Company’s employees (including its executive officers)
through the consummation of the Transactions (the “Closing”), and with the consent of
Celgene, the Company has established this Plan to create an incentive for its eligible employees to
continue their employment with the Company, through the grant of incentive bonuses and retention
awards (“Retention Awards”).

     2. Incentive Bonuses

     (a) Each regular employee of the Company as of December 31, 2007, whether full-time or
part-time (including fixed-term employees), who is not an Eligible U.S. Sales Associate (each, an
“Eligible Employee”) shall be eligible to receive an incentive bonus in respect of the
achievement toward 2007 individual and corporate goals under the Company’s incentive bonus
compensation program (an “Incentive Bonus”). Subject to the final approval of the
Company’s Board of Directors, Incentive Bonuses for 2007 may be paid in amounts up to 200% of an
Eligible Employee’s annual bonus target (a set percentage of the employee’s annual base
compensation rate at the end of the year under review, determined by position level), pro-rated in
the case of Eligible Employees who only worked a partial year in 2007 (with actual amounts to be
determined and approved by the Plan Administrator). A determination of the Incentive Bonuses shall
be based on an evaluation of 2007 individual performance and corporate performance in proportions
previously established by the Company for each employee and shall be paid in March 2008. Except
where prohibited by law, an Eligible Employee must be employed with the Company at the time the
Incentive Bonuses are paid in order to be entitled to receive an Incentive Bonus, if any.

     (b) Each regular full-time, field-based sales employee of the Company based in the United
States (each, an “Eligible U.S. Sales Associate”) shall remain eligible to receive a
quarterly bonus as outlined in the Pharmion Sales Incentive Compensation Plan, and may also be
eligible for an additional “challenge bonus” for each of the first and second quarters of 2008
subject to the achievement of stated Company sales targets (a “Sales Bonus”). Sales
Bonuses shall be paid subject to an Eligible U.S. Sales Associate’s continued employment with the
Company through the end of the calendar quarter to which such Sales Bonus corresponds.

 

 

     3. Retention Awards

     (a) Each regular full-time and part-time employee of the Company (including each fixed-term
employee) who was actively employed by the Company as of November 18, 2007, or had accepted an
offer of employment on or before November 18, 2007, and continues to be employed by the Company
through the Closing shall receive a Retention Award calculated as follows:

     (i) If the Closing occurs on or before June 1, 2008, the Retention Award shall equal
25% of such employee’s Base Salary (as defined below); and

     (ii) If the Closing occurs after June 1, 2008, the Retention Award shall equal 50% of
such employee’s Base Salary.

For purposes hereof, the term “Base Salary” shall mean an employee’s annual base
compensation rate for services paid by the Company, as reflected in the Company’s payroll
records as of December 1, 2007; provided, however, that for a fixed-term employee who is
employed for a term of fewer than 12 months, “Base Salary” shall mean such
fixed-term employee’s base compensation rate for the number of full months employed by the
Company as of the date of the Closing. Base Salary shall not include commissions, bonuses,
overtime pay, incentive compensation, benefits paid under any qualified plan, any group
medical, dental, or other welfare benefit plan, non-cash compensation, or any other
additional compensation, but shall include amounts reduced pursuant to such employee’s
salary reduction agreement under Section 125, 132(f)(4), or 401(k) of the Internal Revenue
Code of 1986, as amended (the “Code”), if any, or a nonqualified elective deferred
compensation arrangement, if any, to the extent that in each such case the reduction is to
base salary.

     (b) All Retention Awards payable pursuant to this Section 3 shall be (i) paid as soon as
practicable, but not later than thirty (30) days following the Closing and (ii) subject to
reduction for all applicable income and employment withholding taxes and other regular payroll
deductions.

     (c) Notwithstanding anything contained in this Section 3 to the contrary, if an employee’s
employment with the Company is terminated for any reason prior to the Closing, such employee shall
immediately forfeit any right to receive a Retention Award under the Plan and shall have no further
rights with respect thereto. If an employee’s employment with the Company is terminated for any
reason on or after the Closing, such employee shall be paid the Retention Award as provided in this
Section 3 notwithstanding such termination of employment.

     4. Section 280G

     (a) Notwithstanding any provision of this Plan to the contrary, if any payments or benefits an
employee would receive from the Company under this Plan or otherwise in connection with the
Transactions (the “Total Payments”) (i) constitute “parachute payments” within the meaning
of Section 280G of the Code and (ii) but for this Section 4, would be subject to the excise tax
imposed by Section 4999 of the Code, then such employee will be entitled to receive either (x) the
full amount of the Total Payments or (y) a portion of the Total Payments

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having a value equal to $1 less than three (3) times such individual’s “base amount” (as such
term is defined in Section 280G(b)(3)(A) of the Code), whichever of (x) and (y), after taking into
account applicable federal, state, and local income taxes and the excise tax imposed by Section
4999 of the Code, results in the receipt by such employee on an after-tax basis, of the greatest
portion of the Total Payments. Any determination required under this Section 4 shall be made in
writing by the independent public accountant of the Company immediately prior to the Closing (the
“Accountants”), whose determination shall be conclusive and binding for all purposes upon
the Company and the applicable employee. For purposes of making the calculations required by this
Section 4, the Accountants may make reasonable assumptions and approximations concerning applicable
taxes and may rely on reasonable, good-faith interpretations concerning the application of Sections
280G and 4999 of the Code. If there is a reduction pursuant to this Section 4 of the Total
Payments to be delivered to the applicable employee, such reduction shall first be applied to any
cash amounts to be delivered to the applicable employee under this Plan and thereafter to any other
severance benefits or payments otherwise owing to such applicable employee.

     (b) Notwithstanding anything herein to the contrary, in the event the applicable employee is
entitled to a tax gross-up with respect to excise taxes under Section 4999 of the Code pursuant to
an employment or other written agreement with the Company in effect as of November 18, 2007, and
which has been disclosed to Celgene prior to such date, this Section 4 shall not apply to such
employee, no portion of the Total Payments shall be so reduced as set forth herein, and such
employment or other agreement shall govern with respect to the subject matter covered by the
provisions of this Section 4.

     5. Plan Administration

     (a) The Plan shall be administered by the Board of Directors of the Company or a duly
authorized committee thereof (the “Plan Administrator”). Subject to the express provisions
of this Plan, the Plan Administrator shall have sole authority to interpret the Plan (including any
vague or ambiguous provisions) and to make all other determinations deemed necessary or advisable
for the administration of the Plan. Decisions of the Plan Administrator shall be made by a
majority of its members attending a meeting at which a quorum is present (which meeting may be held
telephonically), or by written action in accordance with applicable law. All determinations and
interpretations of the Plan Administrator shall be final, binding, and conclusive as to all
persons.

     (b) Neither the Plan Administrator nor any employee, officer, agent, or director of the
Company shall be personally liable by reason of any action taken with respect to the Plan for any
mistake of judgment made in good faith, and the Company shall indemnify and hold harmless each
employee, officer, agent, or director of the Company, including the Plan Administrator, to whom any
duty or power relating to the administration or interpretation of the Plan may be allocated or
delegated, against any reasonable cost or expense (including counsel fees) or liability (including
any sum paid in settlement of a claim with the approval of the Plan Administrator) arising out of
any act or omission to act in connection with the Plan unless arising out of such person’s own
fraud, bad faith, or gross negligence.

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     (c) The Plan Administrator may delegate any and all of its powers and responsibilities
hereunder to other persons.

     (d) The Plan Administrator shall maintain such accounts and records regarding the fiscal and
other transactions of this Plan and such other data as may be required to carry out its functions
under this Plan and to comply with all applicable laws.

     6. Right to Amend or Terminate Plan

     The Company reserves the right to amend, in whole or in part, any or all of the provisions of
this Plan by action of the Plan Administrator at any time and for any reason, provided that in no
event shall any amendment adversely impact a participant’s rights hereunder. Notwithstanding
anything herein to the contrary, the Plan may not be terminated prior to the date on which all
benefits hereunder have been paid in full.

     7. No Guarantee of Employment

     This Plan is not a guarantee of continued employment for any employee of the Company,
including any employee potentially eligible for benefits hereunder. An employee’s employment
remains terminable at any time with or without cause by either the employee or the Company or,
after the Closing, Celgene.

     8. Applicable Law

     This Plan and all action taken under it shall be governed as to validity, construction,
interpretation, and administration by the laws of the State of Delaware (without regard to the
choice of law principles thereof) and any applicable U.S. federal law.

     9. Unfunded Status

     This Plan shall be “unfunded,” and all benefits that become payable hereunder shall be paid
out of the general assets of the Company. All participants in the Plan shall be solely unsecured
general creditors of the Company. If the Company decides in its sole discretion to establish any
advance accrued reserve on its books against the future expense of the benefits payable hereunder,
or if the Company decides in its sole discretion to fund a trust under this Plan, such reserve or
trust shall not under any circumstances be deemed to be an asset of this Plan.

     10. Successors

     For purposes of this Plan, the Company shall include any and all successors and assignees,
whether direct or indirect, by purchase, merger, consolidation, or otherwise, to all or
substantially all of the business or assets of the Company, and such successors and assignees shall
perform the Company’s obligations under this Plan, in the same manner and to the same extent that
the Company would be required to perform if no such succession or assignment had taken place. In
such event, the term “Company,” as used in this Plan, shall mean the Company, as herein before
defined and any successor or assignee to the business or assets which by reason hereof becomes
bound by the terms and provisions of this Plan.

4

 

     11. General Provisions

     (a) This Plan is not a term or condition of any individual’s employment, and the Company
maintains the right to change the terms and conditions of a participant’s employment, including,
without limitation, demotion, discipline, promotion, compensation, benefits, duties, and location
of performance, at any time with or without cause and/or with or without notice. No employee shall
have any legal right to payments hereunder except to the extent all conditions relating to the
receipt of such payments have been satisfied in accordance with the terms of this Plan as set forth
herein.

     (b) Nothing contained herein shall give an employee any right to any employee benefit upon
termination of employment with the Company, except as specifically provided herein.

     (c) No person having a benefit under this Plan may assign, transfer, or in any other way
alienate any benefit hereunder, nor shall any benefit under this Plan be subject to garnishment,
attachment, execution, or levy of any kind.

     (d) Neither the establishment of this Plan, nor any modification thereof, nor the payment of
any benefits hereunder, shall be construed as giving to any participant or other person any legal
or equitable right against the Company or the Plan Administrator, or any fiduciary, employee, or
agent of the Company.

     (e) The Company shall have the right to make such provisions as it deems necessary or
appropriate to satisfy any obligations it reasonably believes it may have to withhold for federal,
state, or local income or other taxes incurred by reason of payments pursuant to this Plan. In
lieu thereof, the Company shall have the right to withhold the amounts of such taxes from any other
sums due or to become due from the Company to a participant upon such terms and conditions as the
Plan Administrator may prescribe.

     (f) Should any provision of the Plan be deemed or held to be unlawful or invalid for any
reason, such fact shall not adversely affect the other provisions of the Plan unless such
determination shall render impossible or impracticable the functioning of the Plan, and in such
case, an appropriate provision or provisions shall be adopted so that the Plan may continue to
function properly.

     (g) Any benefits payable under this Plan shall not be deemed salary or other compensation to a
participant for the purposes of computing benefits to which he or she may be entitled under any
pension plan or other arrangement of the Company maintained for the benefit of its employees,
unless such plan or arrangement provides otherwise.

     (h) In the event that the Plan Administrator finds that a participant is unable to care for
his or her affairs because of illness or accident, then benefits payable hereunder, unless claim
has been made therefor by a duly appointed guardian, committee, or other legal representative, may
be paid in such manner as the Plan Administrator shall determine, and the application thereof shall
be a complete discharge of all liability for any payments or benefits to which such participant was
or would have been otherwise entitled under this Plan.

5

 

     (i) Any payments to a minor from this Plan may be paid by the Plan Administrator in its sole
and absolute discretion (i) directly to such minor, (ii) to the legal or natural guardian of such
minor, or (iii) to any other person, whether or not appointed guardian of the minor, who shall have
the care and custody of such minor. The receipt by such individual shall be a complete discharge
of all liability under the Plan therefor.

     (j) All announcements, notices, and other communications regarding this Plan will be made by
the Company in writing (whether in electronic form or otherwise). Except for written amendments to
the Plan or official written communications issued by the Company in connection with the Plan,
participants in the Plan may not rely on any representation or statement made by the Company or its
affiliates or any of its or their officers, directors, employees, or agents, whether written or
oral, regarding such participants’ participation in the Plan and any rights thereunder.

     As adopted by the Board of Directors of Pharmion Corporation and to become
effective as of January 21, 2008

	 	 	 	 	 
	By:  	/s/ Erle T. Mast	 	 
	 	Name:  	Erle T. Mast 	 	 
	 	Title:  	Executive Vice President and Chief Financial Officer 	 
	 

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