Document:

Exhibit 10.5

                          REGISTRATION RIGHTS AGREEMENT

     This  Registration  Rights  Agreement  ("Agreement"), dated as of July 14,
2006,  is  made  by  and between SimplaGene USA, Inc., a Nevada corporation (the
"Company"),  and Crusader Securities, LLC, a New York limited liability company,
member  NASD  ("Crusader")  and  is  entered  into  by  the  Company  in partial
consideration  of the fees that are owed by the Company to Crusader, pursuant to
an  Engagement  Letter  between  the  Company and Crusader dated April 15, 2005.

     The  Company  and  Crusader  hereby  agree  as  follows:

     1.     Definitions.  1.     Definitions.
            -----------          -----------

"Advice"  shall  have  the  meaning  set  forth  in  Section  6(c).
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"Commission"  means  the  United  States  Securities  and  Exchange  Commission.
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"Effectiveness  Date"  means  the  date  of  any  order issued by the Commission
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pursuant  to  which  any  Registration  Statement  becomes  effective  under the
Securities  Act  of  1933  ("Securities  Act").

"Effectiveness  Period"  means  the  period  from  the Effectiveness Date to the
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earlier  of  the  date all Registrable Securities have been sold and transferred
free of restriction on transfer by reference to the registration requirements of
the  Securities  Act,  or  December  1,  2007.

"Filing  Date"  means  the  date  the  Company  proposes  to file a Registration
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Statement  with  the  Commission.

"Holder"  or  "Holders" means Crusader Securities, LLC, its parents, affiliates,
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and/or subsidiaries, and 21st Century Associates, LLC ("21st Century"), to which
the  Company,  notwithstanding  anything  to  the  contrary herein, approves and
acknowledges Crusader will transfer a portion of the Registrable Securities, and
who  are  collectively  the  holder or holders, as the case may be, from time to
time  of  Registrable  Securities;  provide,  however,  21st  Century  and  any
subsequent  Holder,  in  order to get the benefits of this Agreement, must agree
with  the  Company  to  be  bound  by  the  terms  hereof.

"Indemnified  Party"  shall  have  the  meaning  set  forth  in  Section  5(c).
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"Indemnifying  Party"  shall  have  the  meaning  set  forth  in  Section  5(c).
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"Losses"  shall  have  the  meaning  set  forth  in  Section  5(a).
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"Proceeding"  means  an  action,  claim,  suit,  investigation  or  proceeding
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(including,  without limitation, an investigation or partial proceeding, such as
a  deposition),  whether  commenced  or  threatened.

"Prospectus"  means  the  prospectus  included  in  the  Registration  Statement
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(including,  without  limitation,  a  prospectus  that  includes any information
previously  omitted from a prospectus filed as part of an effective registration
statement  in  reliance upon Rule 430A promulgated under the Securities Act), as
amended  or supplemented by any prospectus supplement, with respect to the terms
of  the  offering  of  any  portion of the Registrable Securities covered by the
Registration  Statement,  and  all  other  amendments  and  supplements  to  the
Prospectus,  including  post-effective amendments, and all material incorporated
by  reference  or  deemed  to  be  incorporated by reference in such Prospectus.

"Registrable  Securities" means all of the shares of common stock of the Company
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registered  in the name of Crusader as of the date hereof or as may be re-issued
thereafter  in  connection  with the subsequent transfer of shares of the common
stock  of the Company from Crusader to 21st Century, together with any shares of
common  stock  issued  or  issuable  upon  any  stock  split,  dividend or other
distribution,  recapitalization  or similar event with respect to the foregoing.
In  addition,  Registrable  Securities shall include all of the shares of common
stock  of  the  Company  represented  by  subsequent certificates re-issued from
Crusader  to  21st  Century.

"Registration  Statement" means each registration statement filed by the Company
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as  described  in Section 2, including (in each case) the Prospectus, amendments
and  supplements to the registration statement or Prospectus, including pre- and
post-effective  amendments,  all exhibits thereto, and all material incorporated
by  reference  or  deemed  to  be  incorporated by reference in the registration
statement.

"Rule  415"  means  Rule  415  promulgated  by  the  Commission  pursuant to the
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Securities  Act,  as  such Rule may be amended from time to time, or any similar
rule  or regulation hereafter adopted by the Commission having substantially the
same  purpose  and  effect  as  such  Rule.

"Rule  424"  means  Rule  424  promulgated  by  the  Commission  pursuant to the
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Securities  Act,  as  such Rule may be amended from time to time, or any similar
rule  or regulation hereafter adopted by the Commission having substantially the
same  purpose  and  effect  as  such  Rule.

     2.     Registration.  If  at any time prior to December 1, 2007 the Company
            ------------
shall determine to prepare and file with the Commission a Registration Statement
relating  to  an offering for its own account or the account of others under the
Securities  Act  of any of its equity securities, other than on Form S-4 or Form
S-8  (each  as  promulgated  under the Securities Act) or their then equivalents
relating  to  equity  securities  to  be  issued  solely  in connection with any
acquisition  of  any  entity  or  business  or  equity  securities  issuable  in
connection  with  stock option or other employee benefit plans, then the Company
shall  send to each Holder a written notice of such determination and, if within
fifteen  days after the date of such notice, any such Holder shall so request in
writing,  the  Company  shall  include in such Registration Statement all or any
part  of such Registrable Securities such Holder requests to be registered. Each
Holder  agrees  to  furnish to the Company a completed questionnaire in the form
attached  to  this  Agreement as Annex A (a "Selling Holder Questionnaire") with
                                             ----------------------------
its  written  request  for  inclusion  of  its  Registrable  Securities  in  the
Registration Statement and provide such other information as may be required for
inclusion into the Registration Statement.  The Company shall not be required to
include  the  Registrable Securities of a Holder in a Registration Statement who
fails to furnish to the Company a fully completed Selling Holder Questionnaire,.

     3.     Registration  Procedures.  In  connection  with  the  Company's
            ------------------------
registration  obligations  hereunder,  the  Company  shall:

     (a)     Not  less  than  five  days  prior  to the filing of a Registration
Statement  or any related Prospectus or any amendment or supplement thereto, the
Company  shall  furnish  to  the  Holders  copies  of the "Selling Stockholders"
section  of  such  document,  the  "Plan  of  Distribution"  and any risk factor
contained  in  such document that addresses specifically this transaction or the
Selling Stockholders, as proposed to be filed which documents will be subject to
the  review of such Holders.  Any corrections provided by a Holder by the end of
the  third  day following receipt of such draft documents may be included in the
filing  without further notice or approval of the Holder.  The Company shall not
file  a  Registration  Statement  or  any  such  Prospectus or any amendments or
supplements  thereto  that  contains  any  disclosure regarding the Holders that
varies  from  the  disclosure  set forth in the Selling Holder Questionnaire (as
corrected  by  the  Holders), without the prior approval of the affected Holder.

     (b)     Use  commercially  reasonable  efforts to prepare and file with the
Commission  such  amendments,  including  post-effective  amendments,  to  the
Registration Statement and the Prospectus used in connection therewith as may be
necessary  to  keep  the Registration Statement continuously effective as to the
applicable  Registrable  Securities for the Effectiveness Period and prepare and
file  with  the  Commission  such additional Registration Statements in order to
register  for resale under the Securities Act all of the Registrable Securities,
cause  the  related  Prospectus  to  be  amended or supplemented by any required
Prospectus supplement, and as so supplemented or amended to be filed pursuant to
Rule  424;

     (c)     Respond as promptly as reasonably possible to any comments received
from  the Commission with respect to the Registration Statement or any amendment
thereto  and,  as  promptly  as  reasonably  possible, upon request, provide the
Holders  true  and  complete  copies  of  all  correspondence  from  and  to the
Commission  relating  to  the  Registration  Statement;

     (d)     Notify the Holders of Registrable Securities to be sold as promptly
as reasonably possible and (if requested by any such Person) confirm such notice
in writing promptly following the day (i)(A) when a Prospectus or any Prospectus
supplement or post-effective amendment to the Registration Statement is proposed
to  be filed; (B) when the Commission notifies the Company whether there will be
a "review" of the Registration Statement and whenever the Commission comments in
writing  on  the  Registration Statement (the Company shall upon request provide
true  and  complete  copies thereof and all written responses thereto to each of
the  Holders);  and  (C)  with  respect  to  the  Registration  Statement or any
post-effective  amendment,  when  the  same  has  become  effective; (ii) of any
request  by  the Commission or any other Federal or state governmental authority
during  the period of effectiveness of the Registration Statement for amendments
or  supplements  to  the  Registration Statement or Prospectus or for additional
information;  (iii)  of  the  issuance by the Commission or any other federal or
state  governmental  authority of any stop order suspending the effectiveness of
the  Registration Statement covering any or all of the Registrable Securities or
the  initiation  of any Proceedings for that purpose; (iv) of the receipt by the
Company  of any notification with respect to the suspension of the qualification
or exemption from qualification of any of the Registrable Securities for sale in
any  jurisdiction,  or  the initiation or threatening of any Proceeding for such
purpose;  and  (v)  of the occurrence of any event or passage of time that makes
the  financial  statements included in the Registration Statement ineligible for
inclusion  therein  or  any  statement  made  in  the  Registration Statement or
Prospectus  or any document incorporated or deemed to be incorporated therein by
reference  untrue  in any material respect or that requires any revisions to the
Registration  Statement,  Prospectus  or other documents so that, in the case of
the  Registration  Statement  or the Prospectus, as the case may be, it will not
contain  any  untrue  statement of a material fact or omit to state any material
fact  required to be stated therein or necessary to make the statements therein,
in  light  of  the circumstances under which they were made, not misleading.

     (e)     Use  commercially  reasonable efforts to avoid the issuance of, or,
if  issued,  obtain the withdrawal of (i) any order suspending the effectiveness
of  the  Registration Statement, or (ii) any suspension of the qualification (or
exemption  from  qualification) of any of the Registrable Securities for sale in
any  jurisdiction,  at  the  earliest  practicable  moment.

     (f)     Furnish to each Holder, without charge, at least one conformed copy
of  the  Registration  Statement and each amendment thereto, including financial
statements  and  schedules,  all  documents  incorporated  or  deemed  to  be
incorporated  therein  by  reference to the extent requested by such Person, and
all  exhibits to the extent requested by such Person (including those previously
furnished  or  incorporated  by  reference)  promptly  after  the filing of such
documents  with  the Commission.

     (g)  Promptly deliver to each Holder, without charge, as many copies of the
Prospectus  or  Prospectuses  (including  each  form  of  prospectus)  and  each
amendment  or  supplement  thereto  as  such  Persons  may reasonably request in
connection  with resales by the Holder of Registrable Securities. Subject to the
terms  of  this  Agreement,  the  Company  hereby  consents  to  the use of such
Prospectus  and  each  amendment  or  supplement  thereto by each of the selling
Holders  in  connection with the offering and sale of the Registrable Securities
covered by such Prospectus and any amendment or supplement thereto, except after
the  giving  of  any  notice  pursuant  to  Section  3(d).

     (h)     Prior to any resale of Registrable  Securities by a Holder, use its
commercially  reasonable  efforts  to  register or qualify or cooperate with the
selling  Holders  in  connection  with  the  registration  or  qualification (or
exemption from the Registration or qualification) of such Registrable Securities
for  resale  by  the  Holder  under  the  securities  or  Blue  Sky laws of such
jurisdictions  within  the  United  States  as any Holder reasonably requests in
writing,  to  keep  the  Registration or qualification (or exemption there from)
effective  during  the  Effectiveness Period and to do any and all other acts or
things  reasonably  necessary to enable the disposition in such jurisdictions of
the Registrable Securities covered by the Registration Statement; provided, that
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the  Company  shall  not  be required to qualify generally to do business in any
jurisdiction  where  it  is  not  then  so qualified, subject the Company to any
material tax in any such jurisdiction where it is not then so subject, or file a
general consent to service of process in any such jurisdiction.

     (i)  If  requested by the Holders, cooperate with the Holders to facilitate
the  timely  preparation  and  delivery of certificates representing Registrable
Securities  to  be  delivered  to  a  transferee  pursuant  to  the Registration
Statement,  which  certificates shall be free of all restrictive legends, and to
enable such Registrable Securities to be in such denominations and registered in
such  names  as  any  such  Holders  may  request.

     (j)     Upon  the  occurrence of any event contemplated by Section 3(d)(v),
as promptly as reasonably possible, prepare a supplement or amendment, including
a post-effective amendment, to the Registration Statement or a supplement to the
related  Prospectus  or  any  document incorporated or deemed to be incorporated
therein  by  reference,  and  file  any  other  required  document  so  that, as
thereafter  delivered,  neither  the  Registration Statement nor such Prospectus
will  contain an untrue statement of a material fact or omit to state a material
fact  required to be stated therein or necessary to make the statements therein,
in  light  of  the  circumstances  under  which  they were made, not misleading.

If  the Company notifies the Holders in accordance with clauses (ii) through (v)
of  Section  3(d) above to suspend the use of any Prospectus until the requisite
changes to such Prospectus have been made, then the Holders shall suspend use of
such  Prospectus.  The  Company will use its best efforts to ensure that the use
of  the  Prospectus  may  be  resumed  as  promptly  as  is  practicable.

     (k)     Comply with all applicable rules and regulations of the Commission.
(i)     If  the  Company  notifies  the  Holders in accordance with clauses (ii)
through (v) of Section 3(d) above to suspend the use of any Prospectus until the
requisite  changes  to  such  Prospectus have been made, the Company may require
each  selling  Holder to furnish to the Company a further certified statement as
to  the  number of shares of Common Stock beneficially owned by such Holder and,
if  required  by  the  Commission,  the  person  thereof  that  has  voting  and
dispositive  control over the Shares.

     4.     Registration  Expenses.  All  fees  and  expenses  incident  to  the
            ----------------------
performance  of  or compliance with this Agreement by the Company shall be borne
by  the  Company  whether or not any Registrable Securities are sold pursuant to
the  Registration Statement.  The fees and expenses referred to in the foregoing
sentence shall include, without limitation, (i) all registration and filing fees
(including,  without  limitation,  fees and expenses (A) with respect to filings
required  to  be  made with the trading market on which the Common Stock is then
listed  for  trading,  and (B) in compliance with applicable state securities or
Blue  Sky laws), (ii) printing expenses (including, without limitation, expenses
of  printing  certificates  for  Registrable  Securities  and, if applicable, of
printing  prospectuses),  (iii) messenger, telephone and delivery expenses, (iv)
fees  and disbursements of counsel for the Company, (v) Securities Act liability
insurance,  if the Company so desires such insurance, and (vi) fees and expenses
of all other Persons retained by the Company in connection with the consummation
of  the  transactions  contemplated by this Agreement.  In addition, the Company
shall  be  responsible  for  all of its internal expenses incurred in connection
with  the  consummation  of  the  transactions  contemplated  by  this Agreement
(including,  without  limitation,  all salaries and expenses of its officers and
employees  performing  legal  or  accounting  duties), the expense of any annual
audit  and  the fees and expenses incurred in connection with the listing of the
Registrable  Securities on any securities exchange as required hereunder.  In no
event  shall the Company be responsible for any broker or similar commissions or
any  legal fees or other costs of the Holders.
     5.     Indemnification
            ---------------

     (a)     Indemnification by the Company.  The Company shall, notwithstanding
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any  termination of this Agreement, indemnify and hold harmless each Holder, the
officers,  directors,  agents  and  employees  of  each of them, each Person who
controls any such Holder (within the meaning of Section 15 of the Securities Act
or  Section  20  of  the  Exchange  Act) and the officers, directors, agents and
employees  of  each  such controlling Person, to the fullest extent permitted by
applicable  law,  from  and  against  any  and  all  losses,  claims,  damages,
liabilities,  costs  (including, without limitation, reasonable attorneys' fees)
and  expenses  (collectively, "Losses"), as incurred, arising out of or relating
                               ------
to  any  untrue  or alleged untrue statement of a material fact contained in the
Registration  Statement,  any  Prospectus  or  any  form of prospectus or in any
amendment or supplement thereto or in any preliminary prospectus, or arising out
of  or  relating to any omission or alleged omission of a material fact required
to be stated therein or necessary to make the statements therein (in the case of
any  Prospectus  or  form  of  prospectus or supplement thereto, in light of the
circumstances  under which they were made) not misleading, except to the extent,
but  only  to the extent, that (i) such untrue statements or omissions are based
solely  upon  information  regarding  such  Holder  furnished  in writing to the
Company  by  such  Holder  expressly for use therein, or to the extent that such
information  relates  to  such  Holder  or  such  Holder's  proposed  method  of
distribution  of  Registrable Securities and was reviewed and expressly approved
in  inewriting  by  such Holder expressly for use in the Registration Statement,
such  Prospectus  or  such  form of Prospectus or in any amendment or supplement
thereto  (it  being  understood  that the Holder has approved Annex A hereto for
this  purpose)  or  (ii)  in  the  case of an occurrence of an event of the type
specified  in  Section  3(d)(ii)-(v),  the  use by such Holder of an outdated or
defective  Prospectus after the Company has notified such Holder in writing that
the  Prospectus is outdated or defective and prior to the receipt by such Holder
of  the  Advice  contemplated  in  Section  6(c).  The  Company shall notify the
Holders  promptly  of  the institution, threat or assertion of any Proceeding of
which  the  Company is aware in connection with the transactions contemplated by
this  Agreement.

     (b)     Indemnification  by  Holders.  Each Holder shall, severally and not
             ----------------------------
jointly,  indemnify  and  hold  harmless  the  Company, its directors, officers,
agents  and  employees, each Person who controls the Company (within the meaning
of Section 15 of the Securities Act and Section 20 of the Exchange Act), and the
directors,  officers,  agents  or  employees of such controlling Persons, to the
fullest  extent  permitted  by  applicable  law, from and against all Losses, as
incurred,  to  the extent arising out of or based solely upon: (x) such Holder's
failure  to  comply  with the prospectus delivery requirements of the Securities
Act  or  (y) any untrue or alleged untrue statement of a material fact contained
in  any Registration Statement, any Prospectus, or any form of prospectus, or in
any amendment or supplement thereto or in any preliminary prospectus, or arising
out  of  or  relating  to  any  omission  or alleged omission of a material fact
required  to  be  stated therein or necessary to make the statements therein not
misleading (i) to the extent, but only to the extent, that such untrue statement
or  omission  is  contained  in  any information so furnished in writing by such
Holder  to  the Company specifically for inclusion in the Registration Statement
or  such  Prospectus  or  (ii)  to the extent that (1) such untrue statements or
omissions  are  based solely upon information regarding such Holder furnished in
writing  to  the  Company  by  such  Holder expressly for use therein, or to the
extent  that  such  information relates to such Holder or such Holder's proposed
method  of distribution of Registrable Securities and was reviewed and expressly
approved  in  writing  by  such  Holder  expressly  for  use in the Registration
Statement  (it  being understood that the Holder has approved Annex A hereto for
this purpose), such Prospectus or such form of Prospectus or in any amendment or
supplement  thereto  or (2) in the case of an occurrence of an event of the type
specified  in  Section  3(d)(ii)-(v),  the  use by such Holder of an outdated or
defective  Prospectus after the Company has notified such Holder in writing that
the  Prospectus is outdated or defective and prior to the receipt by such Holder
of  the Advice contemplated in Section 6(c).  In no event shall the liability of
any  selling Holder hereunder be greater in amount than the dollar amount of the
net proceeds received by such Holder upon the sale of the Registrable Securities
giving  rise  to  such  indemnification  obligation.

     (c)     Conduct of Indemnification Proceedings. If any  Proceeding shall be
             ---------------------------------------
brought  or  asserted  against  any  Person  entitled to indemnity hereunder (an
"Indemnified  Party"),  such  Indemnified Party shall promptly notify the Person
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from  whom  indemnity  is  sought (the "Indemnifying Party") in writing, and the
                                        ------------------
Indemnifying Party shall have the right to assume the defense thereof, including
the  employment  of counsel reasonably satisfactory to the Indemnified Party and
the  payment  of  all  fees  and  expenses  incurred  in connection with defense
thereof; provided, that the failure of any Indemnified Party to give such notice
shall  not  relieve  the  Indemnifying  Party  of its obligations or liabilities
pursuant  to  this  Agreement,  except (and only) to the extent that it shall be
finally  determined by a court of competent jurisdiction (which determination is
not subject to appeal or further review) that such failure shall have prejudiced
the  Indemnifying  Party.  An  Indemnified  Party shall have the right to employ
separate  counsel  in  any  such  Proceeding  and  to participate in the defense
thereof,  but  the  fees and expenses of such counsel shall be at the expense of
such Indemnified Party or Parties unless:  (i) the Indemnifying Party has agreed
in writing to pay such fees and expenses; (ii) the Indemnifying Party shall have
failed  promptly  to assume the defense of such Proceeding and to employ counsel
reasonably  satisfactory  to  such  Indemnified Party in any such Proceeding; or
(iii) the named parties to any such Proceeding (including any impleaded parties)
include  both  such  Indemnified  Party  and  the  Indemnifying  Party, and such
Indemnified  Party shall reasonably believe that a material conflict of interest
is  likely to exist if the same counsel were to represent such Indemnified Party
and  the  Indemnifying  Party (in which case, if such Indemnified Party notifies
the  Indemnifying  Party in writing that it elects to employ separate counsel at
the expense of the Indemnifying Party, the Indemnifying Party shall not have the
right  to assume the defense thereof and the reasonable fees and expenses of one
separate  counsel  shall  be  at  the  expense  of the Indemnifying Party).  The
Indemnifying Party shall not be liable for any settlement of any such Proceeding
effected  without  its  written consent, which consent shall not be unreasonably
withheld.  No Indemnifying Party shall, without the prior written consent of the
Indemnified Party, effect any settlement of any pending Proceeding in respect of
which  any  Indemnified  Party  is  a  party, unless such settlement includes an
unconditional  release  of  such  Indemnified Party from all liability on claims
that  are  the  subject  matter  of  such  Proceeding.

     (d)     Payment  As  Incurred.  Subject to the terms of this Agreement, all
             ---------------------
reasonable fees and expenses of the Indemnified Party (including reasonable fees
and  expenses  to  the  extent  incurred  in  connection  with  investigating or
preparing  to  defend  such  Proceeding  in  a manner not inconsistent with this
Section) shall be paid to the Indemnified Party, as incurred, within ten Trading
Days  of  written  notice  thereof to the Indemnifying Party; provided, that the
                                                              --------
Indemnified  Party  shall  promptly  reimburse  the  Indemnifying Party for that
portion  of  such  fees  and  expenses applicable to such actions for which such
Indemnified Party is not entitled to indemnification hereunder, determined based
upon  the  relative  faults  of  the  parties.

     (e)     Contribution.  If a claim for indemnification under Section 5(a) or
             ------------
5(b)  is  unavailable  to  an  Indemnified  Party (by reason of public policy or
otherwise),  then  each  Indemnifying  Party,  in  lieu  of  indemnifying  such
Indemnified  Party,  shall  contribute  to  the  amount  paid or payable by such
Indemnified  Party  as  a  result  of  such  Losses,  in  such  proportion as is
appropriate  to  reflect  the  relative  fault  of  the  Indemnifying  Party and
Indemnified  Party  in connection with the actions, statements or omissions that
resulted  in such Losses as well as any other relevant equitable considerations.
The  relative  fault  of  such Indemnifying Party and Indemnified Party shall be
determined  by reference to, among other things, whether any action in question,
including  any untrue or alleged untrue statement of a material fact or omission
or alleged omission of a material fact, has been taken or made by, or relates to
information  supplied  by, such Indemnifying Party or Indemnified Party, and the
parties'  relative  intent,  knowledge, access to information and opportunity to
correct  or  prevent  such  action,  statement  or omission.  The amount paid or
payable by a party as a result of any Losses shall be deemed to include, subject
to  the  limitations  set  forth in this Agreement, any reasonable attorneys' or
other  reasonable fees or expenses incurred by such party in connection with any
Proceeding to the extent such party would have been indemnified for such fees or
expenses  if  the  indemnification provided for in this Section was available to
such party in accordance with its terms.  The parties hereto agree that it would
not  be  just  and  equitable if contribution pursuant to this Section 5(e) were
determined by pro rata allocation or by any other method of allocation that does
not  take  into  account  the  equitable  considerations  referred  to  in  the
immediately preceding paragraph.  Notwithstanding the provisions of this Section
5(e), no Holder shall be required to contribute, in the aggregate, any amount in
excess of the amount by which the proceeds actually received by such Holder from
the  sale  of  the  Registrable Securities subject to the Proceeding exceeds the
amount  of  any  damages  that such Holder has otherwise been required to pay by
reason  of  such  untrue  or  alleged  untrue  statement  or omission or alleged
omission,  except in the case of fraud by such Holder.

     (f)     The indemnity and contribution agreements contained in this Section
are  in  addition to any liability that the Indemnifying Parties may have to the
Indemnified  Parties.
     6.     Miscellaneous
            -------------

     (a)     Remedies.  In  the event of a breach by the Company or by a Holder,
             --------
of any of their obligations under this Agreement, each Holder or the Company, as
the case may be, in addition to being entitled to exercise all rights granted by
law and under this Agreement, including recovery of damages, will be entitled to
specific  performance  of its rights under this Agreement.  The Company and each
Holder  agree  that monetary damages would not provide adequate compensation for
any losses incurred by reason of a breach by it of any of the provisions of this
Agreement  and  hereby  further  agrees  that,  in  the  event of any action for
specific  performance in respect of such breach, it shall waive the defense that
a  remedy  at law would be adequate.
     (b)   Compliance. Each Holder covenants and agrees that it will comply with
           ----------
the  prospectus  delivery requirements of the Securities Act as applicable to it
in  connection with sales of Registrable Securities pursuant to the Registration
Statement.

     (c) Discontinued Disposition. Each Holder agrees by its acquisition of such
         ------------------------
Registrable  Securities  that,  upon receipt of a notice from the Company of the
occurrence  of any event of the kind described in Section 3(d), such Holder will
forthwith  discontinue  disposition  of  such  Registrable  Securities under the
Registration  Statement  until  such  Holder's  receipt  of  the  copies  of the
supplemented  Prospectus  and/or  amended  Registration Statement or until it is
advised  in writing (the "Advice") by the Company that the use of the applicable
                          ------
Prospectus  may  be  resumed,  and,  in  either case, has received copies of any
additional  or  supplemental  filings  that  are  incorporated  or  deemed to be
incorporated  by  reference  in  such Prospectus or Registration Statement.  The
Company  will  use its best efforts to ensure that the use of the Prospectus may
be  resumed  as  promptly as it practicable.

     (d) Amendments and Waivers. The provisions of this Agreement, including the
         ----------------------
provisions  of  this sentence, may not be amended, modified or supplemented, and
waivers  or  consents to departures from the provisions hereof may not be given,
unless the same shall be in writing and signed by the Company and each Holder of
the  then  outstanding  Registrable  Securities.

     (e)     Notices. Except as otherwise provided  herein, all notices or other
             -------
communications  or  deliveries  required  or  permitted to be provided hereunder
shall  be  in writing and shall be deemed given and effective on the earliest of
(i)  the  date of transmission, if such notice or communication is delivered via
facsimile  at  the  facsimile  number  set forth on the signature pages attached
hereto  prior  to  5:00  p.m.  (New  York  time) on a business day, (b) the next
business  day after the date of transmission, if such notice or communication is
delivered via facsimile at the facsimile number set forth on the signature pages
attached hereto on a day that is not a business day or later than 5:00 p.m. (New
York  time)  on any business day, (c) the second business day following the date
of  mailing, if sent by U.S. nationally recognized overnight courier service, or
(d)  upon  actual  receipt  by  the  party to whom such notice is required to be
given.  The address for such notices and communications shall be as set forth on
the  signature  pages  attached  hereto.

     (f)    Successors and Assigns. This Agreement shall inure to the benefit of
            -----------------------
and be binding upon the successors and permitted assigns of each of the parties.

     (g)     Execution  and  Counterparts. This Agreement may be executed in any
             ----------------------------
number  of counterparts, each of which when so executed shall be deemed to be an
original  and,  all  of  which  taken together shall constitute one and the same
Agreement.  In  the  event  that  any  signature  is  delivered  by  facsimile
transmission,  such  signature  shall  create  a valid binding obligation of the
party  executing  (or  on whose behalf such signature is executed) the same with
the  same  force  and  effect  as  if such facsimile signature were the original
thereof.

     (h)   Governing Law. This Agreement shall be governed by and interpreted in
           -------------
accordance  with  the  laws  of  the state of New York.

     (i)    Cumulative Remedies. The remedies provided herein are cumulative and
            -------------------
not exclusive of any remedies provided by law.

     (j)   Severability. If any term, provision, covenant or restriction of this
           ------------
Agreement  is  held by a court of competent jurisdiction to be invalid, illegal,
void  or  unenforceable,  the  remainder of the terms, provisions, covenants and
restrictions set forth herein shall remain in full force and effect and shall in
no  way  be  affected, impaired or invalidated, and the parties hereto shall use
their commercially reasonable efforts to find and employ an alternative means to
achieve  the  same or substantially the same result as that contemplated by such
term,  provision, covenant or restriction.  It is hereby stipulated and declared
to  be  the intention of the parties that they would have executed the remaining
terms, provisions, covenants and restrictions without including any of such that
may  be  hereafter  declared  invalid,  illegal,  void  or  unenforceable.

     (k)     Headings.  The  headings  in  this Agreement are for convenience of
             --------
reference  only  and shall not limit or otherwise affect the meaning hereof.

     7.     Rule 144 Reporting.  With a view to making available the benefits of
            ------------------
certain rules and regulations of the Commission which may at any time permit the
sale  of  the  Registrable Securities to the public without registration, at all
times  the  Company  agrees  to  use  commercially  reasonable  efforts  to:

     (a)  make  and  keep  public  information  available,  as  those  terms are
understood  and  defined  in  Rule  144  under  the  Securities  Act;

     (b)  file  with  the  Commission  in  a timely manner all reports and other
documents required of the Company under the Securities Act and the Exchange Act;
and

     (c)  furnish  to  each Holder forthwith upon request a written statement by
the  Company  as  to its compliance with the reporting requirements of such Rule
144  and  of  the Securities Act and the Exchange Act, a copy of the most recent
annual  or quarterly report of the Company, and such other reports and documents
so filed by the Company as such Holder may reasonably request in availing itself
of  any  rule  or  regulation of the Commission allowing such holder to sell any
Registrable  Securities  without  registration.

<PAGE>

IN  WITNESS  WHEREOF,  the  parties  hereto have caused this Registration Rights
Agreement  to  be duly executed by their respective authorized signatories as of
the  date  first  indicated  above.

                              SIMPLAGENE USA, INC.

By   Paul A. Roman
Its  President and CEO

                            CRUSADER SECURITIES, LLC

By   Blair A West
Its  Managing Director

Address:
Crusader  Securities,  LLC
67  Hampton  Road
Suite  7
Southampton,  New  York  11968
631-702-2900
631-702-2911  (f)

<PAGE>

                                     ANNEX A
                              SIMPLAGENE USA, INC.
                 SELLING SECURITYHOLDER NOTICE AND QUESTIONNAIRE

   The undersigned beneficial owner of common stock, $0.001 par value per share
(the "Common Stock"), of SimplaGene USA, Inc. (the "Company"), (the "Registrable
      ------------                                  -------          -----------
 Securities") understands that the Company has filed or intends to file with the
  ----------
  Securities and Exchange Commission (the "Commission") a registration statement
                                           ----------
    on Form SB-2 or other available form (the "Registration Statement") for the
                                               ----------------------
registration and resale under Rule 415 of the Securities Act of 1933, as amended
   (the "Securities Act"), of the Registrable Securities, in accordance with the
         --------------
     terms of the Registration Rights Agreement dated as of July 14, 2006 (the
  "Registration Rights Agreement"), between the Company and Crusader.  A copy of
        ------------------------
 the Registration Rights Agreement is available from the Company upon request at
the address set forth below.  All capitalized terms not otherwise defined herein
 shall have the meanings ascribed thereto in the Registration Rights Agreement.
Certain legal consequences arise from being named as a selling securityholder in
the Registration Statement and the related prospectus.  Accordingly, holders and
   beneficial owners of Registrable Securities are advised to consult their own
   securities law counsel regarding the consequences of being named or not being
 named as a selling securityholder in the Registration Statement and the related
                                   prospectus.

                                     NOTICE

  The undersigned beneficial owner (the "Selling Securityholder") of Registrable
                                         ----------------------
  Securities hereby elects to include the Registrable Securities owned by it and
   listed below in Item 3 (unless otherwise specified under such Item 3) in the
                             Registration Statement.

<PAGE>

   The undersigned hereby provides the following information to the Company and
           represents and warrants that such information is accurate:

                                  QUESTIONNAIRE
1.     NAME.
     (a)     Full  Legal  Name  of  Selling  Securityholder

     (b)     Full Legal Name of Registered Holder (if not the same as (a) above)
through  which  Registrable  Securities  Listed  in  Item  3  below  are  held:

     (c)     Full  Legal  Name  of Natural Control Person (which means a natural
person  who  directly  you  indirectly alone or with others has power to vote or
dispose  of  the  securities  covered  by  the  questionnaire):

2.  ADDRESS  FOR  NOTICES  TO  SELLING  SECURITYHOLDER:

Telephone:
----------
Fax:
Contact  Person:

3.  BENEFICIAL  OWNERSHIP  OF  REGISTRABLE  SECURITIES:
     (a)     Type and Principal Amount of Registrable Securities (the securities
you  are  entitled to sell under the Registration Rights Agreement) beneficially
owned:

4.  BROKER-DEALER  STATUS:
     (a)     Are  you  a  broker-dealer?
     Yes     No
     Note:     If  yes,  the Commission's staff has indicated that you should be
identified  as  an  underwriter  in  the  Registration  Statement.
     (b)     Are  you  an  affiliate  of  a  broker-dealer?
     Yes     No
     (c)     If you are an affiliate of a broker-dealer, do you certify that you
obtained  the  Registrable Securities in the ordinary course of business, and at
the  time  you  obtained the the Registrable Securities to be resold, you had no
agreements  or  understandings,  directly  or  indirectly,  with  any  person to
distribute  the  Registrable  Securities?
     Yes     No
     Note:     If  no,  the  Commission's staff has indicated that you should be
identified  as  an  underwriter  in  the  Registration  Statement.

5.  BENEFICIAL OWNERSHIP OF OTHER SECURITIES OF THE COMPANY OWNED BY THE SELLING
SECURITYHOLDER.
 Except as set forth below in this Item 5, the undersigned is not the beneficial
 or registered owner of any securities of the Company other than the Registrable
                       Securities listed above in Item 3.
     (a)     Type  and  Amount  of  Other  Securities  beneficially owned by the
Selling  Securityholder  (other  than  the  securities listed in Item 3, above):

<PAGE>

6.  RELATIONSHIPS  WITH  THE  COMPANY:

   Except as set forth below, neither the undersigned nor any of its affiliates,
   officers, directors or principal equity holders (owners of 5% of more of the
equity securities of the undersigned) has held any position or office or has had
     any other material relationship with the Company (or its predecessors or
                    affiliates) during the past three years.

     State  any  exceptions  here:

   The undersigned agrees to promptly notify the Company of any inaccuracies or
changes in the information provided herein that may occur subsequent to the date
     hereof at any time while the Registration Statement remains effective.
 By signing below, the undersigned consents to the disclosure of the information
  contained herein in its answers to Items 1 through 6 and the inclusion of such
    information in the Registration Statement and the related prospectus.  The
undersigned understands that such information will be relied upon by the Company
   in connection with the preparation or amendment of the Registration Statement
  and the related prospectus.  The undersigned further understands and agrees to
   promptly provide to the Company such other information as may be requested by
      the Company as necessary for inclusion in the Registration Statement.
   IN WITNESS WHEREOF the undersigned, by authority duly given, has caused this
Notice and Questionnaire to be executed and delivered either in person or by its
                             duly authorized agent.

Dated:  July  14,  2006          Beneficial  Owner:  Crusader  Securities,  LLC

   /s/Blair A. West
   ----------------
          Signature

   PLEASE FAX A COPY OF THE COMPLETED AND EXECUTED NOTICE AND QUESTIONNAIRE, AND
            RETURN THE ORIGINAL BY OVERNIGHT MAIL, TO THE COMPANY AT:

                        NEW COLORADO PRIME HOLDINGS, INC.
                             500 BI-COUNTY BOULEVARD
                                    SUITE 400
                           FARMINGDALE, NEW YORK 11735Exhibit 10.6

                              ____________________
                              SimplaGene USA, Inc.
                              ____________________

    This offering consists of $2,500,000 of the Company's 5 Year Convertible
                         Debentures convertible into the
                           Company's Common Stock and
                          Warrants exercisable into the
                             Company's Common Stock.

                              ____________________
                             SUBSCRIPTION AGREEMENT
                               ___________________

<PAGE>

                             SUBSCRIPTION PROCEDURES

     Convertible  Debentures (the "Debentures") and Warrants (the "Warrants") of
SIMPLAGENE  USA,  INC  a  Nevada Corporation (the "Company") are being offered .
This  offering is being made in accordance with the exemptions from registration
provided  for  under Section 4(2) of the Securities Act of 1933, as amended (the
"1933  Act")  and  Rule  506  of  Regulation  D  promulgated under the 1933 Act.

     In order to purchase Debentures and Warrants, each subscriber must complete
and  execute  a questionnaire (the "Questionnaire") and a subscription agreement
(the "Subscription Agreement"). In addition, the Holder, as defined herein, must
make  a  payment  for  the  amount being purchased directly to the Company.  All
subscriptions  are  subject  to acceptance by the Company, which shall not occur
until  the  Company  has  returned  the  signed  Company  Signature  Page.

          The  Questionnaire is designed to enable the Holder to demonstrate the
minimum  legal  requirements under federal and state securities laws to purchase
the  Debentures.  The  Signature Page for the Questionnaire and the Subscription
Agreement  contain  representations  relating  to the subscription and should be
reviewed  carefully  by  each  subscriber.

     If  you  are  a  foreign  person or foreign entity, you may be subject to a
withholding  tax  equal  to  thirty  percent  (30%) of any dividends paid by the
Company.  In order to eliminate or reduce such withholding tax you must submit a
properly  executed I.R.S. Form 4224 (Exemption from Withholding of Tax on Income
Effectively  Connected  with  the  Conduct  of a Trade or Business in the United
States)  or I.R.S. Form 1001 (Ownership Exemption or Reduced Trade Certificate),
claiming  exemption  from  withholding or eligibility for treaty benefits in the
form  of  a  lower  rate  of  withholding  tax  on  interest  or  dividends.

     Payment  of  the  full subscription amount will be made by wire transfer by
Dutchess  Private  Equities  Fund, LP and Dutchess Private Equities Fund, II, LP
(the "Holder") on or prior to the closing per the wire instructions that will be
established.  In  the event of a termination of the offering or the rejection of
a  subscription,  subscription  funds  will  be  returned by the Company without
interest  or  charges.

<PAGE>

THE  SECURITIES OFFERED HEREBY HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT
OF 1933, AS AMENDED, OR ANY STATE SECURITIES LAWS AND ARE BEING OFFERED AND SOLD
IN  RELIANCE ON EXEMPTIONS FROM THE REGISTRATION REQUIREMENTS OF SUCH LAWS.  THE
SECURITIES ARE SUBJECT TO RESTRICTIONS ON TRANSFERABILITY AND RESALE AND MAY NOT
BE  TRANSFERRED  OR  RESOLD  EXCEPT  AS  PERMITTED  UNDER  SUCH LAWS PURSUANT TO
REGISTRATION  OR  AN EXEMPTION THEREFROM.  THE SECURITIES HAVE NOT BEEN APPROVED
OR DISAPPROVED BY THE SECURITIES AND EXCHANGE COMMISSION OR ANY OTHER REGULATORY
AUTHORITY, NOR HAVE ANY OF THE FOREGOING AUTHORITIES PASSED UPON OR ENDORSED THE
MERITS  OF  THIS OFFERING OR THE ACCURACY OR ADEQUACY OF THE OFFERING MATERIALS.
ANY  REPRESENTATION  TO  THE  CONTRARY  IS  UNLAWFUL.

                             SUBSCRIPTION AGREEMENT
                            -----------------------

To:     SimplaGene,  Inc.
        -----------------

     This Subscription Agreement ("Agreement") is made between SimplaGene USA, a
                                                              ----------------
Nevada  corporation (the "Company"), and the undersigned prospective Holder (the
"Holder")  who  is  subscribing  hereby for the Company's convertible debentures
(the  "Debentures")  and  warrants  (the  "Warrants")  on  July 14,  2006.  This
subscription is submitted to you in accordance with and subject to the terms and
conditions  described  in  this  Agreement,  together with any Exhibits thereto,
relating  to  an  offering (the "Offering") of Two Million Five Hundred Thousand
dollars  ($2,500,000)  of  Debentures  and  Warrants. The Offering is limited to
accredited  Investors  and  is  made  in  accordance  with  the  exemptions from
registration  provided  for  under  Section 4(2) of the 1933 Act and Rule 506 of
Regulation  D  promulgated  under  the  1933  Act  ("Regulation  D").

     Contemporaneously  with  the  execution and delivery of this Agreement, the
parties  hereto  are  executing  and  delivering a Debenture Registration Rights
Agreement,  the  Debenture  Agreement,  Security Agreement and Warrant Agreement
(collectively,  the  "Transaction  Documents").

1.     SUBSCRIPTION.
       ------------

     (a)  The  closing  shall  be  deemed to have occurred on July 14, 2006 (the
"Closing  Date"  or  a  "Closing")  provided  however,  that  the  transactions
comtemplated by the Agreement and Plan of Reorganization between the Company and
New  Colorado  Prime  Holdings,  Inc,  and all of its subsidiaries has completed
("Acquisition").  The  Company  shall pay ten percent (10%) annual coupon on the
unpaid principal amount of this Debenture (the "Debenture") at such times and in
such  amounts  as  outlined  in  the  Debenture  Agreement.

     (b)     Upon  receipt  by  the  Company  of  the  requisite payment for the
Debentures being purchased, the Debentures so purchased will be forwarded by the
Company  to  the  Holder or its broker, as listed on the signature page, and the
name  of  the  Holder  will be registered on the Debenture transfer books of the
Company  as  the  record  owner  of  such  Debentures.

     (c)     During  the Lock-up Period (as defined in Section 3(v), below), the
Holder  shall  have  the  right,  to  change  the  terms  for the balance of the
Debenture  it then holds, to match the terms of any other offering of securities
made  by  the  Company for the first twelve (12) months as outlined in Section 3
(v)  herein.

     (d)   The  Holder  shall  fund  one  million two hundred and fifty thousand
dollars  ($1,250,000)  upon the closing of the Acquisition and an additional one
million  two  hundred  and fifty thousand dollars ($1,250,000) simultaneously on
the  date  the  registration  statement covering this Offering is filed with the
United  States  Securities  and  Exchange  Commission  ("SEC").

     (e)  The Holder will be granted a security interest in all of the Company's
and  its  Subsidiaries'  assets,  currently  owned  or hereinafter acquired, (as
defined  in  Schedule  3(a)  of  this Agreement), as more fully set forth in the
Security  Agreement  between  the  Company  and  the  Holder  of  this  date.

2.     REPRESENTATIONS  AND  WARRANTIES  OF  THE  HOLDER.
       -------------------------------------------------
     The  Holder hereby represents and warrants to, and agrees with, the Company
as  follows:

     (a)     The  Holder  has  been  furnished  with, and has carefully read the
applicable  form  of  Warrant,  Debenture Registration Rights Agreement, and the
Debenture  and  is familiar with and understands the terms of the Offering. With
           ---
respect to tax and other economic considerations involved in his investment, the
Holder  is  not  relying on the Company. The Holder has carefully considered and
has, to the extent the Holder believes such discussion necessary, discussed with
the  Holder's  professional  legal,  tax,  accounting and financial advisors the
suitability  of  an  investment in the Company, by purchasing the Debentures and
Warrants,  for  the  Holder  's  particular  tax and financial situation and has
determined that the investment being made by the Holder is a suitable investment
for  the  Holder.

     (b)     The  Holder  acknowledges  that  all  documents, records, and books
pertaining  to  this  investment  which the Holder has requested, have been made
available  for  inspection,  or  the  Holder  has  had  access  thereto.

     (c)     The Holder has had a reasonable opportunity to ask questions of and
receive  answers  from  a  person  or  persons  acting  on behalf of the Company
concerning  the  Offering,  and  if  such  opportunity  was taken, then all such
questions  have  been  answered  to  the  full  satisfaction  of  the  Holder.

     (d)     The  Holder  will not sell, or otherwise dispose of the Debentures,
Warrants  or  the  Common  Stock  issued  upon  conversion  of the Debentures or
Warrants  without registration under the 1933 Act or applicable state securities
laws  or  compliance  with  an exemption therefrom including but not limited to:
Rule  144A or 144(k), promulgated under the Securities Act of 1933 (herein after
referred  to  as  an  "Exemption").  The  Debentures  and Warrants have not been
registered under the 1933 Act or under the securities laws of any state. Resales
of  the Common Stock underlying the Debentures and Warrants or issued in payment
of  accrued  interest  on  the  Debentures  are  to be registered by the Company
pursuant  to  the  terms  of  the  Debenture  Registration  Rights  Agreement
incorporated  herein  and  made  a  part  hereof.

     (e)     The  Holder  recognizes  that  an  investment in the Debentures and
Warrants involves substantial risks, including loss of the entire amount of such
investment.  Further, the Holder has carefully read and considered the schedules
attached  hereto.

     (f)     The  Holder  acknowledges  that  each  certificate representing the
Debentures  and  Warrants (and the shares of Common Stock issued upon conversion
of  the  Debentures  or  Warrants,  unless  registered  or issued pursuant to an
Exemption)  or  in  payment  of  interest  on the Debentures shall be stamped or
otherwise  imprinted  with  a  legend  substantially  in  the  following  form:

THE  SECURITIES  EVIDENCED  BY  THIS  CERTIFICATE  MAY  NOT  BE OFFERED OR SOLD,
TRANSFERRED,  PLEDGED, HYPOTHECATED OR OTHERWISE DISPOSED OF EXCEPT (i) PURSUANT
TO  AN  EFFECTIVE  REGISTRATION  STATEMENT  UNDER THE SECURITIES ACT OF 1933, AS
AMENDED,  (ii)  TO THE EXTENT APPLICABLE, PURSUANT TO RULE 144 UNDER THE ACT (OR
ANY  SIMILAR  RULE UNDER SUCH ACT RELATING TO THE DISPOSITION OF SECURITIES), OR
(iii)  PURSUANT  TO  AN  AVAILABLE  EXEMPTION  FROM REGISTRATION UNDER SUCH ACT.

     If the Holder sends a Notice of Conversion (See Exhibit A attached hereto),
and  provided  a  registration  statement under the Securities Act of 1933 is in
effect  as  to  the sale, then in such event the Company shall have its transfer
agent  send  Holder  the  appropriate  number  of shares of Common Stock without
restrictive  legends  (other  than a legend referring to the resale registration
and  prospectus  delivery  requirements)  and  not  subject  to  stop  transfer
instructions.

     (g)     If  this Subscription Agreement is executed and delivered on behalf
of  a  corporation  or  legal  entity  other  than  a  natural person:  (i) such
corporation or other entity has the full legal right and power and all authority
and  approval  required  (a)  to execute and deliver, or authorize execution and
delivery  of  this  Subscription  Agreement  and all other Transaction Documents
executed  and  delivered  by or on behalf of such corporation in connection with
the  purchase  of  the Debentures and Warrants, and (b) to purchase and hold the
Debentures  and  Warrants; and (ii) the signature of the party signing on behalf
of  such  corporation  or  entity  is  binding  upon  such  corporation.

     (h)     The  Holder  is not subscribing for the Debentures or Warrants as a
result  of,  or  pursuant  to,  any  advertisement,  article,  notice  or  other
communication published in any newspaper, magazine or similar media or broadcast
over  television  or  radio  or  presented  at  any  seminar  or  meeting.

      (i)     The  Holder  is purchasing the Debentures and Warrants for its own
account  for  investment,  and not with a view toward the resale or distribution
thereof, except pursuant to sales registered or exempted from registration under
the  1933  Act. The Holder has not offered or sold any portion of the Debentures
and  Warrants  being  acquired nor does the Holder have any present intention of
dividing  the  Debentures or Warrants with others or of selling, distributing or
otherwise  disposing  of  any  portion  of  the  Debentures  or  Warrants either
currently or after the passage of a fixed or determinable period of time or upon
the  occurrence  or non-occurrence of any predetermined event or circumstance in
violation  of the 1933 Act provided, however, that by making the representations
herein,  the  Holder  does  not agree to hold any of the Debentures, Warrants or
shares of Common Stock underlying the Debentures or Warrants, for any minimum or
other  specific  term  and  reserves  the  right  to  dispose of the Debentures,
Warrants or shares of Common Stock underlying the Debentures or Warrants, at any
time  in accordance with or pursuant to a registration statement or an exemption
under  the  1933 Act.  The Holder is neither an underwriter of, nor a dealer in,
the Debentures, Warrants or the Common Stock issuable upon conversion thereof or
upon  the  payment  of  interest  thereon  and  is  not  participating  in  the
distribution  or  resale  of  the  Debentures  or the Common Stock issuable upon
conversion  or  exercise  thereof.

     (j)     The Holder or the Holder's representatives, as the case may be, has
such  knowledge  and  experience in financial, tax and business matters so as to
enable  the  Holder  to  utilize the information made available to the Holder in
connection  with  the Offering to evaluate the merits and risks of an investment
in  the Debentures and Warrants and to make an informed investment decision with
respect  thereto.   The  Holder  is  an  "accredited  investor"  as  defined  in
Regulation  D.

     (k)  The  Holder  or  any  of its affiliates has not, will not and will not
cause  any  person or entity, directly or indirectly, to engage in "short sales"
of  the  Company's  Common  Stock as long as the Transaction Documents remain in
effect.

3.     REPRESENTATIONS  AND  WARRANTIES  OF  THE  COMPANY.
       --------------------------------------------------

     Except  as  set  forth  in  the  Schedules  attached  hereto,  the  Company
represents  and  warrants  to  the  Holder  that:

     a.     Organization  and Qualification.  The Company and its "SUBSIDIARIES"
            -------------------------------
(which for purposes of this Subscription Agreement means any entity in which the
Company,  directly  or  indirectly,  owns  capital  stock  or holds an equity or
similar  interest)  (a complete list of which is set forth in Schedule 3(a)) are
corporations duly organized and validly existing in good standing under the laws
of  the  respective jurisdictions of their incorporation, and have the requisite
corporate  power and authorization to own their properties and to carry on their
business  as now being conducted. Both the Company and its Subsidiaries are duly
qualified to do business and are in good standing in every jurisdiction in which
their  ownership  of  property  or  the nature of the business conducted by them
makes  such qualification necessary, except to the extent that the failure to be
so qualified or be in good standing would not have a Material Adverse Effect. As
used  in  this  Subscription  Agreement,  "MATERIAL  ADVERSE  EFFECT"  means any
material adverse effect on the business, properties, assets, operations, results
of  operations,  financial  condition  or  prospects  of  the  Company  and  its
Subsidiaries,  if  any,  taken  as  a whole, or on the transactions contemplated
hereby  or  by  the  agreements and instruments to be entered into in connection
herewith,  or  on  the  authority  or  ability  of  the  Company  to perform its
obligations  under the Transaction Documents (as defined in Section 3(b) below).

     b.     Authorization;  Enforcement; Compliance with Other Instruments.  (i)
            --------------------------------------------------------------
The  Company  has  the requisite corporate power and authority to enter into and
perform  its  obligations  under  the  Transaction  Documents,  and to issue the
Debentures  in  accordance with the terms hereof and thereof, (ii) the execution
and delivery of the Transaction Documents by the Company and the consummation by
it  of  the transactions contemplated hereby and thereby, and validly authorized
by  the  Company's Board of Directors and no further consent or authorization is
required  by the Company, its Board of Directors, or its shareholders, (iii) the
Transaction  Documents  have been duly and validly executed and delivered by the
Company,  and  (iv)  the  Transaction Documents constitute the valid and binding
obligations  of  the  Company enforceable against the Company in accordance with
their  terms, except as such enforceability may be limited by general principles
of  equity  or  applicable  bankruptcy,  insolvency, reorganization, moratorium,
liquidation or similar laws relating to, or affecting generally, the enforcement
of  creditors'  rights  and  remedies.

     c.     Capitalization.  As of the date hereof, the authorized capital stock
            --------------
of the Company consists of 50,000,000 shares of Common Stock, of which as of the
date hereof, approximately 30,000,000 shares are issued and outstanding.  All of
such  outstanding shares have been, or upon issuance will be, validly issued and
are  fully  paid  for  and  nonassessable.  Except as disclosed in Schedule 3(c)
which  is  attached hereto and made a part hereof (i) no shares of the Company's
capital  stock  are  subject to preemptive rights or any other similar rights or
any  liens  or encumbrances suffered or permitted by the Company, (ii) there are
no outstanding debt securities, (iii) there are no outstanding shares of capital
stock, options, warrants, scrip, rights to subscribe to, calls or commitments of
any  character whatsoever relating to, or securities or rights convertible into,
any  shares  of  capital  stock  of  the  Company or any of its Subsidiaries, or
contracts,  commitments,  understandings or arrangements by which the Company or
any  of  its  Subsidiaries  is or may become bound to issue additional shares of
capital  stock  of  the Company or any of its Subsidiaries or options, warrants,
scrip,  rights to subscribe to, calls or commitments of any character whatsoever
relating  to,  or  securities  or rights convertible into, any shares of capital
stock of the Company or any of its Subsidiaries, (iv) there are no agreements or
arrangements  under which the Company or any of its Subsidiaries is obligated to
register  the  sale of any of their securities under the 1933 Act (except the as
otherwise  set forth in the Transaction Documents), (v) there are no outstanding
securities  of  the  Company  or  any  of  its  Subsidiaries  which  contain any
redemption  or  similar  provisions,  and  there  are no contracts, commitments,
understandings  or  arrangements by which the Company or any of its Subsidiaries
is  or  may  become  bound  to  redeem  a  security of the Company or any of its
Subsidiaries,  (vi)  there  are  no  securities  or  instruments  containing
anti-dilution  or  similar  provisions that will be triggered by the issuance of
the  Securities  as  described in this Subscription Agreement, (vii) the Company
does  not  have  any  stock  appreciation  rights  or  "phantom  stock" plans or
agreements  or  any similar plan or agreement, and (viii) there is no dispute as
to the class of any shares of the Company's capital stock. The Company will have
furnished  to  the Holder, or the Holder will have access through EDGAR to, true
and  correct  copies of the Company's Articles of Incorporation, as in effect on
the date hereof (the "ARTICLES OF INCORPORATION"), and the Company's By-laws, as
in  effect  on  the  date  hereof  (the  "BY-LAWS  ') within thirty (30) days of
Closing.

     d.     Issuance  of  Debentures.     A  sufficient  number  of  Debentures
            ------------------------
issuable pursuant to this Subscription Agreement, but not more than 4.99% of the
shares  of  Common Stock outstanding as of the date hereof (if, and only if, the
Company  becomes listed on Nasdaq or the American Stock Exchange), has been duly
authorized  and  reserved  for issuance pursuant to this Subscription Agreement.
Upon  issuance  in  accordance  with this Subscription Agreement, the Debentures
will  be  validly  issued,  fully  paid  for and nonassessable and free from all
taxes,  liens  and  charges  with respect to the issue thereof. In the event the
Company  cannot  register  a sufficient number of shares of Common Stock, due to
the  remaining  number  of authorized shares of Common Stock being insufficient,
the  Company  will use its best efforts to register the maximum number of shares
it can based on the remaining balance of authorized shares and will use its best
efforts  to  increase  the number of its authorized shares as soon as reasonably
practicable.

     e.     No  Conflicts.  The  execution,  delivery  and  performance  of  the
            -------------
Transaction  Documents by the Company and the consummation by the Company of the
transactions  contemplated hereby and thereby will not (i) result in a violation
of  the  Articles of Incorporation, any Certificate of Designations, Preferences
and  Rights  of  any outstanding series of preferred stock of the Company or the
By-laws  or  (ii)  conflict  with, or constitute a material default (or an event
which  with  notice  or  lapse  of time or both would become a material default)
under,  or  give to others any rights of termination, amendment, acceleration or
cancellation  of,  any  material  agreement,  contract,  indenture  mortgage,
indebtedness  or instrument to which the Company or any of its Subsidiaries is a
party, or result in a violation of any law, rule, regulation, order, judgment or
decree,  including  United  States  federal  and  state  securities  laws  and
regulations  and  the rules and regulations of the principal securities exchange
or  trading market on which the Common Stock is traded or listed (the "Principal
Market"),  applicable  to the Company or any of its Subsidiaries or by which any
property  or  asset  of  the  Company  or  any  of  its Subsidiaries is bound or
affected.  Except  as  disclosed  in  Schedule 3(e), neither the Company nor its
Subsidiaries  is  in violation of any term of, or in default under, the Articles
of Incorporation, any Certificate of Designations, Preferences and Rights of any
outstanding  series  of  preferred  stock of the Company or the By-laws or their
organizational  charter  or  by-laws,  respectively, or any contract, agreement,
mortgage,  indebtedness, indenture, instrument, judgment, decree or order or any
statute,  rule  or  regulation  applicable  to  the Company or its Subsidiaries,
except  for  possible  conflicts,  defaults,  terminations,  amendments,
accelerations,  cancellations  and  violations that would not individually or in
the  aggregate  have  a Material Adverse Effect. The business of the Company and
its  Subsidiaries  is  not  being  conducted,  and  shall  not  be conducted, in
violation  of  any  law,  statute,  ordinance,  rule, order or regulation of any
governmental  authority  or  agency,  regulatory  or  self-regulatory agency, or
court,  except  for  possible  violations  the  sanctions  for  which  either
individually  or  in  the  aggregate  would  not have a Material Adverse Effect.
Except  as  specifically  contemplated  by  this  Subscription  Agreement and as
required  under the 1933 Act, the Company is not required to obtain any consent,
authorization,  permit  or  order of, or make any filing or registration (except
the filing of a registration statement)  with, any court, governmental authority
or  agency,  regulatory  or self-regulatory agency or other third party in order
for  it  to  execute,  deliver  or  perform  any  of  its  obligations under, or
contemplated  by,  the Transaction Documents in accordance with the terms hereof
or  thereof.  All  consents,  authorizations,  permits,  orders,  filings  and
registrations  which the Company is required to obtain pursuant to the preceding
sentence  have  been obtained or effected on or prior to the date hereof and are
in  full force and effect as of the date hereof. Except as disclosed in Schedule
3(e), the Company and its Subsidiaries are unaware of any facts or circumstances
which  might give rise to any of the foregoing. The Company is not, and will not
be,  in  violation  of  the  listing  requirements of the Principal Market as in
effect  on  the date hereof and on each of the Closing Dates and is not aware of
any  facts  which  would reasonably lead to delisting of the Common Stock by the
Principal  Market  in  the  foreseeable  future.

     f.     SEC  Documents;  Financial  Statements.  The  Company  has filed all
            --------------------------------------
reports,  schedules,  forms, statements and other documents required to be filed
by it with the Securities and Exchange Commission ("SEC") within the past twelve
(12)  months  pursuant  to  the  reporting  requirements  of  the Securities and
Exchange  Act  of 1934 ("1934 Act").  All of the foregoing have been filed since
the  date  hereof and all exhibits included therein and financial statements and
schedules  thereto  and  documents  incorporated  by  reference  therein  being
hereinafter  referred  to  as the "SEC DOCUMENTS"). The Company has delivered to
the  Holder  or  its  representatives, or they have had access through EDGAR, to
true and complete copies of the SEC Documents. As of their respective dates, the
SEC  Documents  complied  in  all material respects with the requirements of the
1934  Act  and  the  rules  and  regulations  of  the SEC promulgated thereunder
applicable to the SEC Documents, and none of the SEC Documents, at the time they
were  filed  with  the SEC, contained any untrue statement of a material fact or
omitted  to  state a material fact required to be stated therein or necessary to
make the statements therein, in light of the circumstances under which they were
made,  and  are  not  misleading.  As  of  their respective dates, the financial
statements  of  the Company included in the SEC Documents complied as to form in
all  material respects with applicable accounting requirements and the published
rules and regulations of the SEC with respect thereto. Such financial statements
have  been prepared in accordance with generally accepted accounting principles,
consistently  applied,  during  the  periods  involved  (except  (i)  as  may be
otherwise  indicated  in such financial statements or the notes thereto, or (ii)
in  the  case  of  unaudited  interim statements, to the extent they may exclude
footnotes  or  may be condensed or summary statements) and fairly present in all
material  respects the financial position of the Company as of the dates thereof
and  the  results  of  its  operations and cash flows for the periods then ended
(subject,  in  the  case  of  unaudited  statements,  to  normal  year-end audit
adjustments).  No  other  written  information  provided  by or on behalf of the
Company  to  the  Holder  which is not included in the SEC Documents, including,
without limitation, information referred to in Section 3(d) of this Subscription
Agreement,  contains  any  untrue statement of a material fact or omits to state
any  material fact necessary to make the statements therein, in the light of the
circumstance  under  which  they  are  or  were  made,  and  are not misleading.

     g.     Absence of Certain Changes.  Except as disclosed in Schedule 3(g) or
            --------------------------
the  SEC  Documents  filed  at  least thirty (30) days prior to the date hereof,
there  has  been  no  change or development in the business, properties, assets,
operations,  financial  condition,  results  of  operations  or prospects of the
Company  or  its  Subsidiaries which has had or reasonably could have a Material
Adverse  Effect, since April 30, 2006.  The Company has not taken any steps, and
does  not currently expect to take any steps, to seek protection pursuant to any
bankruptcy  law  nor  does the Company or its Subsidiaries have any knowledge or
reason  to  believe that its creditors intend to initiate involuntary bankruptcy
proceedings.

     h.     Absence  of  Litigation.  Except  as  set forth in the Company's SEC
            -----------------------
filings,  and  the  year  ended December 25, 2005 audited financials of Colorado
Prime  Holdings,  Inc.,  there  is  no  action,  suit,  proceeding,  inquiry  or
investigation  before  or  by  any  court,  public  board,  government  agency,
self-regulatory  organization  or  body  pending  or,  to  the  knowledge of the
executive  officers of Company or any of its Subsidiaries, threatened against or
affecting  the Company, the Common Stock or any of the Company's Subsidiaries or
any  of  the  Company's  or the Company's Subsidiaries' officers or directors in
their  capacities  as  such,  in which an adverse decision could have a Material
Adverse  Effect.

     i.     Acknowledgment  Regarding  the  Purchase of Debentures.  The Company
            ------------------------------------------------------
acknowledges  and  agrees that the Holder is acting solely in the capacity of an
arm's  length  investor  with  respect  to  the  Transaction  Documents  and the
transactions  contemplated  hereby and thereby. The Company further acknowledges
that the Holder is not acting as a financial advisor or fiduciary of the Company
(or  in  any similar capacity) with respect to the Transaction Documents and the
transactions  contemplated hereby and thereby and any advice given by the Holder
or  any  of  its  respective  representatives  or  agents in connection with the
Transaction  Documents  and  the transactions contemplated hereby and thereby is
merely  incidental  to  the  Holder's  purchase  of  the Debentures. The Company
further  represents  to the Holder that the Company's decision to enter into the
Transaction Documents has been based solely on the independent evaluation by the
Company  and  its  representatives.

     j.     Intentionally  omitted.

     k.     Employee Relations.  Neither the Company nor any of its Subsidiaries
            ------------------
is  involved  in any union labor dispute nor, to the knowledge of the Company or
any of its Subsidiaries, is any such dispute threatened. Neither the Company nor
any of its Subsidiaries is a party to a collective bargaining agreement, and the
Company  and  its  Subsidiaries  believe that relations with their employees are
good.  No  executive  officer  (as  defined  in Rule 501(f) of the 1933 Act) has
notified  the Company that such officer intends to leave the Company's employ or
otherwise  terminate  such  officer's  employment  with  the  Company.

     l.     Intellectual  Property  Rights.  All  patents,  patent applications,
            ------------------------------
trademark  registrations and applications for trademark registration held by the
Company  are  owned  free  and  clear  of  all  mortgages,  liens,  charges  or
encumbrances  whatsoever.  No  licenses  have been granted with respect to these
items  and  the  Company  and  its Subsidiaries do not have any knowledge of any
infringement by the Company or its Subsidiaries of trademark, trade name rights,
patents, patent rights, copyrights, inventions, licenses, service names, service
marks,  service  mark  registrations,  trade  secret  or other similar rights of
others,  and, except as set forth on Schedule 3(l), there is no claim, action or
proceeding  being  made or brought against, or to the Company's knowledge, being
threatened  against,  the Company or its Subsidiaries regarding trademark, trade
name,  patents,  patent  rights,  invention,  copyright, license, service names,
service  marks,  service mark registrations, trade secret or other infringement;
and  the  Company and its Subsidiaries are unaware of any facts or circumstances
which  might give rise to any of the foregoing. The Company and its Subsidiaries
have  taken reasonable security measures to protect the secrecy, confidentiality
and  value  of  all  of  their  intellectual  property.

     m.     Environmental  Laws.  The  Company  and  its Subsidiaries (i) are in
            -------------------
compliance  with  any  and all applicable foreign, federal, state and local laws
and  regulations  relating  to  the  protection  of human health and safety, the
environment  or  hazardous  or  toxic  substances  or  wastes,  pollutants  or
contaminants ("ENVIRONMENTAL LAWS"), (ii) have received all permits, licenses or
other  approvals required of them under applicable Environmental Laws to conduct
their  respective  businesses,  and  (iii)  are in compliance with all terms and
conditions  of  any such permit, license or approval where, in each of the three
foregoing  cases,  the  failure  to so comply would have, individually or in the
aggregate,  a  Material  Adverse  Effect.

     n.     Title.  The  Company  and  its Subsidiaries have good and marketable
            -----
title  in  fee  simple to all real property and good and marketable title to all
personal property owned by them which is material to the business of the Company
and its Subsidiaries, in each case free and clear of all liens, encumbrances and
defects  except  such  as  are  described  in  Schedule  3(n)  or such as do not
materially  affect  the value of such property and do not interfere with the use
made  and  proposed  to  be  made  of such property by the Company or any of its
Subsidiaries.  Any  real property and facilities held under lease by the Company
or  any  of  its  Subsidiaries  are  held  by  them  under valid, subsisting and
enforceable leases with such exceptions as are not material and do not interfere
with  the use made and proposed to be made of such property and buildings by the
Company  and  its  Subsidiaries.

     o.     Insurance.  The  Company and each of its Subsidiaries are insured by
            ---------
insurers  of  recognized  financial responsibility against such losses and risks
and  in  such  amounts  as  management of the Company believes to be prudent and
customary  in  the  businesses  in  which  the  Company and its Subsidiaries are
engaged.  Neither  the  Company  nor  any  such  Subsidiary has been refused any
insurance  coverage  sought  or applied for and neither the Company nor any such
Subsidiary  has  any  reason  to  believe  that it will not be able to renew its
existing  insurance  coverage  as  and  when  such coverage expires or to obtain
similar  coverage  from  similar  insurers  as  may be necessary to continue its
business  at  a  cost  that  would  not  have  a  Material  Adverse  Effect.

     p.     Regulatory  Permits.  The  Company and its Subsidiaries have in full
            -------------------
force  and  effect  all certificates, approvals, authorizations and permits from
the  appropriate  federal,  state,  local  or foreign regulatory authorities and
comparable foreign regulatory agencies, necessary to own, lease or operate their
respective  properties  and  assets and conduct their respective businesses, and
neither  the  Company  nor  any  such  Subsidiary  has  received  any  notice of
proceedings  relating to the revocation or modification of any such certificate,
approval,  authorization  or  permit,  except  for such certificates, approvals,
authorizations  or  permits  which  if  not  obtained,  or  such  revocations or
modifications  which,  would  not  have  a  Material  Adverse  Effect.

     q.     Internal  Accounting  Controls.  The  Company  and  each  of  its
            ------------------------------
Subsidiaries  maintain  a  system  of internal accounting controls sufficient to
provide  reasonable  assurance  that (i) transactions are executed in accordance
with  management's  general  or  specific  authorizations, (ii) transactions are
recorded  as  necessary  to  permit  preparation  of  financial  statements  in
conformity  with  generally accepted accounting principles and to maintain asset
accountability,  (iii)  access  to  assets  is permitted only in accordance with
management's  general  or  specific  authorization,  and  (iv)  the  recorded
accountability  for  assets  is  compared with the existing assets at reasonable
intervals  and  appropriate  action  is  taken  with respect to any differences.

     r.     No Materially Adverse Contracts.  Neither the Company nor any of its
            -------------------------------
Subsidiaries is subject to any charter, corporate or other legal restriction, or
any  judgment,  decree,  order,  rule or regulation which in the judgment of the
Company's  officers  has or is expected in the future to have a Material Adverse
Effect.  Neither  the  Company  nor  any  of  its Subsidiaries is a party to any
contract  or agreement which in the judgment of the Company's officers has or is
expected  to  have  a  Material  Adverse  Effect.

     s.     Tax  Status.  The Company has filed all federal and state income tax
            -----------
returns,  as  required  and the Company and each of its Subsidiaries has made or
filed  all  United  States  federal  and state income and all other tax returns,
reports  and  declarations  required by any jurisdiction to which it is subject.
The  Company  represents  that  there are no unpaid taxes in any material amount
claimed  to be due by the taxing authority of any jurisdiction, and the officers
of  the  Company  know  of  no  basis  for  any  such  claim.

     t.     Certain  Transactions.  Except  as  set  forth  in the SEC Documents
            ---------------------
filed  at  least  ten  days prior to the date hereof and except for arm's length
transactions pursuant to which the Company makes payments in the ordinary course
of  business  upon  terms  no  less favorable than the Company could obtain from
third  parties  and  other than the grant of stock options disclosed on Schedule
3(c),  none of the officers, directors, or employees of the Company is presently
a  party  to  any transaction with the Company or any of its Subsidiaries (other
than for services as employees, officers and directors), including any contract,
agreement  or  other  arrangement providing for the furnishing of services to or
by,  providing  for rental of real or personal property to or from, or otherwise
requiring  payments to or from any officer, director or such employee or, to the
knowledge of the Company, any corporation, partnership, trust or other entity in
which  any officer, director, or any such employee has a substantial interest or
is  an  officer,  director,  trustee  or  partner.

     u.     Dilutive  Effect.  The Company understands and acknowledges that the
            ----------------
number  of  shares  of  Common  Stock  issuable  upon purchases pursuant to this
Subscription Agreement will increase in certain circumstances including, but not
necessarily limited to, the circumstance wherein the trading price of the Common
Stock  declines  following  the  effective  date  of  the registration statement
covering the Common Stock underlying the Debentures (the "Effective Date").  The
Company's executive officers and directors have studied and fully understand the
nature  of  the  transactions  contemplated  by  this Subscription Agreement and
recognize that they have a potential dilutive effect.  The board of directors of
the  Company  has  concluded,  in  its  good  faith  business judgment that such
issuance  is  in  the  best  interests of the Company.  The Company specifically
acknowledges that, subject to such limitations as are expressly set forth in the
Transaction  Documents,  its  obligation  to  issue  shares of Common Stock upon
purchases  pursuant to this Subscription Agreement is absolute and unconditional
regardless  of  the dilutive effect that such issuance may have on the ownership
interests  of  other  shareholders  of  the  Company.

     v.   Additional Financings. With the exceptions set for in this Section v.,
          ---------------------
the  Company  shall  not,  directly  nor  indirectly,  without the prior written
consent  of  the Holder, offer, sell, grant any option to purchase, or otherwise
dispose  of  (or  announce  any  offer, sale, grant or any option to purchase or
other disposition) any of its Common Stock or securities convertible into Common
Stock,  or  file any registration statement, including those on Form S-8 for any
securities  (a  "SUBSEQUENT FINANCING"), in either case ending on the earlier of
(i)  360  (three  hundred  and  sixty)  days  after  the  effective  date of the
registration  statement covering resale of the shares of Common Stock underlying
the  Debentures  (the  "Effective Date") or (ii) the date on which the full Face
Amount,  accrued  interest  and  penalties, if any,  on the Debentures have been
paid  ("Lock  Up Period"), as set forth in the Debenture Agreement.  The Company
shall  be  permitted  to complete a bona fide employee stock option plan ("Stock
Plan"), provided however, that the vesting period for any shares included in the
Stock  Plan are equal to or greater than two (2) years and the shares are priced
at  or  above  the  then  current  market  price  of the Company's Common Stock.

During  the Lock Up Period, the Holder shall retain a first right of refusal for
any  additional  financings.  The  Company  must  submit  to  the  Holder a duly
authorized  term  sheet  of  the  financing and the Holder may elect, in writing
within five (5) days, to exercise its right to finance the Company upon the same
terms and conditions, as set forth in the Debenture Agreement.  In the event the
Holder does not elect to complete such financing within such period, the Company
may  proceed  with  the  proposed  third-party  financing,  and any registration
statements  required  pursuant  to that third-party financing, on the same terms
and  conditions  as  contained  in  the  notice  to  Holder.

 If,  during  the  Lock  Up Period, if the Company issues or agrees to issue any
Common  Stock or securities convertible into or exercisable for shares of Common
Stock  (or  modify  any  of  the foregoing which may be outstanding prior to the
execution  of  this  Agreement)  to any person or entity at a price per share or
conversion  or exercise price per share  less than the Conversion Price, or less
than  the  Warrant  exercise  price  with respect to the Warrant Shares, with or
without  the  consent  of  the Holder, the Conversion Price and Warrant Exercise
Price  shall  automatically  be reduced to a price equal to the price of the new
issuance.  Additionally, if the Company shall issue or agree to issue any of the
aforementioned  securities to any person, firm or corporation at terms deemed by
the  Holder to be more favorable to the other person or entity than the terms or
conditions  of  this  Offering,  then  the  Holder  is granted the right, at its
election,  to  modify any term of this Offering to match any more favorable term
provided  by  the Company to such person or entity.  The rights of the Holder in
this  Section  (v) are in addition to any other right the Holder has pursuant to
this  Subscription  Agreement  and  the  Transaction  Documents.

In  the  event  the  exercise of the rights described in the preceding paragraph
would  result  in  the issuance of an amount of Common Stock of the Company that
would  exceed  the maximum amount that may be issued to the Holder calculated in
the  manner  described  in Section 3 (d) of this Agreement, then the issuance of
such additional shares of Common Stock of the Company to such Subscriber will be
deferred  in  whole  or  in  part  until such time as such Subscriber is able to
beneficially  own  such  Common  Stock  without exceeding the maximum amount set
forth  calculated  in  the  manner described in Section 3 (d) of this Agreement.
The  determination  of when such common stock may be issued shall be made by the
Holder.

w.   Sarbanes-Oxley  Compliance.  The  Company hereby acknowledges that they are
     ---------------------------
current  with the requirement of Sarbanes-Oxley Act of 2002 ("Sarbox"), and will
remain  compliant  with  Sarbox  and  its  rules  and  regulations for reporting
requirements  in the time frame required by Sarbox, and any updates to deadlines
imposed  by  Sarbox.

x.  Code  of  Ethics.  The  Company has adopted and filed or will adopt and will
    -----------------
file a Code of Ethics and has filed the Code with the SEC within sixty (60) days
of  Closing.

y.  No  Disagreements  with  Accountants,  Auditors  and  Lawyers.  There are no
    --------------------------------------------------------------
disagreements  of  any kind presently existing, or reasonably anticipated by the
    -
Company  to arise, between the Company and the accountants, auditors and lawyers
formerly or presently used by the Company, including but not limited to disputes
or  conflicts  over  payment  owed  to  such  accountants,  auditors or lawyers.

z.  Investment Company.  Neither the Company nor any Affiliate is an "investment
    -------------------
company"  within  the  meaning  of  the  Investment  Company  Act  of  1940.

aa.  Company  Predecessor.All representations made by or relating to the Company
     ---------------------
of  a  historical  nature  and all undertaking described herein shall relate and
refer  to  the  Company,  its  predecessors,  and  the  Subsidiaries.

bb.  Option  Plan  Restrictions.  The  only  officer,  director,  employee  and
     --------------------------
consultant  stock  option  or  stock incentive plan is outlined is Section 3 (v)
     --
above.

4.     COVENANTS  OF  THE  COMPANY
       ---------------------------

     a.     Best  Efforts.  The  Company  shall  use  its best efforts timely to
            -------------
satisfy  each  of  the  conditions  to  be  satisfied  by it as provided in this
Subscription  Agreement.

     b.     Blue Sky.  The Company shall, at its sole cost and expense, make all
            --------
filings  and  reports  relating  to the offer and sale of the Debentures and the
Common  Stock  underlying  the  Debentures  as  required  under  the  applicable
securities  or  "Blue Sky" laws of such states of the United States as specified
by  the  Holder  or  as  required  by  law.

     c.     Reporting Status.  Until the earlier of (i) the date that the Holder
            ----------------
may  sell all of the Common Stock underlying the Debentures acquired pursuant to
this  Subscription  Agreement  without  restriction  pursuant  to  Rule  144(k)
promulgated under the 1933 Act (or successor thereto), or (ii) the date on which
the  Holder  shall have sold all the Common Stock underlying the Debentures, the
Company shall file all reports required to be filed with the SEC pursuant to the
1934  Act, and the Company shall not terminate its status as a reporting company
under  the  1934  Act.

     d.     Use  of Proceeds.     The Company shall use the entire proceeds from
            ----------------
this  Debenture  exclusively  to finance the reverse acquisition by New Colorado
Prime  Holdings,  Inc.  of the Company and to further the growth and interest of
the  Company.  Any  other  use  of  the  funds  contemplated  herein,  shall  be
considered  a  breach  of  contract  and  an  event  of  Default.

     e.     Conditions  to  Closing.The  Company shall sign and be in compliance
            ------------------------
with  the  Transaction  Documents  with  the  Holder.

     f.     Financial  Information.  The Company agrees to make available to the
            ----------------------
Holder  via  EDGAR  or other electronic means the following: (i) within five (5)
business  days  after  the  filing  thereof  with  the SEC, a copy of its Annual
Reports  on  Form  10-KSB,  its  Quarterly  Reports  on Form 10-QSB, any Current
Reports on Form 8-K and any Registration Statements or amendments filed pursuant
to  the  1933 Act; (ii) on the same day as the release thereof, facsimile copies
of  all  press  releases issued by the Company or any of its Subsidiaries, (iii)
copies  of  any  notices  and  other  information made available or given to the
shareholders  of  the  Company  generally,  contemporaneously  with  the  making
available or giving thereof to the shareholders and (iv) within two (2) calendar
days  of filing or delivery thereof, copies of all documents filed with, and all
correspondence sent to, the Principal Market, any securities exchange or market,
or  the  National  Association  of  Securities  Dealers,  Inc.

     g.     Reservation of Common Stock.  Subject to the following sentence, the
            ---------------------------
Company  shall  take  all  action necessary to at all times have authorized, and
reserved  for  the  purpose of issuance, a sufficient number of shares of Common
Stock to provide for the issuance of the Common Stock underlying the Debentures.
In  the  event  that  the  Company determines that it does not have a sufficient
number  of  authorized  shares of Common Stock to reserve and keep available for
issuance,  the  Company  shall  use  its  best efforts to increase the number of
authorized  shares  of  Common  Stock  by  seeking  shareholder approval for the
authorization  of  such  additional  shares.  The Holder shall have the right to
reasonably  determine  the  amount  of  shares  to  be re-registered such as are
necessary  to  satisfy  the  terms  of  the  Agreement.

     h.     Listing.  The  Company  shall  promptly secure the listing of all of
            -------
the  Common  Stock  underlying the Debentures upon the Principal Market and each
other  national securities exchange and automated quotation system, if any, upon
which  shares  of  Common  Stock  are then listed (subject to official notice of
issuance)  and  shall  maintain,  such  listing.  The Company shall maintain the
Common  Stock's  authorization for quotation on the Principal Market, unless the
Holder  and  the  Company  agree  otherwise.  Neither the Company nor any of its
Subsidiaries  shall take any action which would be reasonably expected to result
in  the  delisting  or  suspension  of  the Common Stock on the Principal Market
(excluding  suspensions of not more than one trading day resulting from business
announcements  by the Company). The Company shall promptly provide to the Holder
copies  of  any  notices  it  receives  from  the Principal Market regarding the
continued  eligibility  of  the  Common  Stock  for  listing  on  such automated
quotation  system  or  securities  exchange  that  would affect the Registration
Statement.  The  Company  shall  pay  all  fees  and expenses in connection with
satisfying  its  obligations  under  this  Section.

     i.     Transactions  With Affiliates.  During the Lock-Up Period, set forth
            -----------------------------
in  Section  3  (v),  the  Company  shall  not,  and  shall  cause  each  of its
Subsidiaries  not  to,  enter  into,  amend, modify or supplement, or permit any
Subsidiary  to  enter  into,  amend,  modify  or  supplement,  any  agreement,
transaction,  commitment  or  arrangement  with  any  of its or any Subsidiary's
officers,  directors,  persons who were officers or directors at any time during
the  previous  two years, shareholders who beneficially own five percent (5%) or
more of the Common Stock, or affiliates or with any individual related by blood,
marriage or adoption to any such individual or with any entity in which any such
entity  or individual owns a five percent (5%) or more beneficial interest (each
a  "RELATED  PARTY")  during  the  Lock  Up  Period;  except  for  (i) customary
employment  arrangements  and  benefit  programs  on reasonable terms (including
changes  currently  under  discussion  with  the  Company's  Board  of Directors
concerning  the  compensation,  to  be  payable  in  stock), (ii) any agreement,
transaction,  commitment or arrangement on an arms-length basis on terms no less
favorable  than  terms which would have been obtainable from a person other than
such  Related  Party,  or  (iii)  any  agreement,  transaction,  commitment  or
arrangement  which  is  approved by a majority of the disinterested directors of
the  Company.  For  purposes  hereof, any director who is also an officer of the
Company  or  any Subsidiary of the Company shall not be a disinterested director
with  respect  to  any  such  agreement, transaction, commitment or arrangement.
"AFFILIATE"  for  purposes  hereof  means, with respect to any person or entity,
another  person  or  entity that, directly or indirectly, (i) has a five percent
(5%)  or  more  equity  interest in that person or entity, (ii) has five percent
(5%)  or  more  common ownership with that person or entity, (iii) controls that
person  or  entity,  or  (iv)  shares common control with that person or entity.
"CONTROL"  or  "CONTROLS"  for purposes hereof means that a person or entity has
the  power,  direct  or  indirect,  to conduct or govern the policies of another
person  or  entity.

     j.     Corporate  Existence.  The  Company  shall  use  its  commercially
            --------------------
reasonable  best efforts to preserve and continue the corporate existence of the
Company.

     k.     Notice  of Certain Events Affecting Registration.  The Company shall
            ------------------------------------------------
promptly  notify  Holder  upon  the occurrence of any of the following events in
respect  of  a  registration statement or related prospectus covering the Common
Stock  underlying  the  Debentures:  (i)  receipt  of any request for additional
information  by  the  SEC  or  any other federal or state governmental authority
during  the period of effectiveness of the registration statement for amendments
or  supplements  to  the  registration statement or related prospectus; (ii) the
issuance  by the SEC or any other federal or state governmental authority of any
stop  order  suspending  the  effectiveness of any registration statement or the
initiation  of  any  proceedings  for  that  purpose;  (iii)  receipt  of  any
notification  with  respect  to the suspension of the qualification or exemption
from qualification of any of the Common Stock underlying the Debentures for sale
in  any jurisdiction or the initiation or threatening of any proceeding for such
purpose;  (iv)  the happening of any event that makes any statement made in such
registration  statement  or  related  prospectus or any document incorporated or
deemed to be incorporated therein by reference untrue in any material respect or
that  requires  the making of any changes in the registration statement, related
prospectus  or  documents  so  that, in the case of a registration statement, it
will  not  contain  any untrue statement of a material fact or omit to state any
material  fact required to be stated therein or necessary to make the statements
therein  not misleading, and that in the case of the related prospectus, it will
not  contain  any  untrue  statement  of  a  material  fact or omit to state any
material  fact required to be stated therein or necessary to make the statements
therein,  in  the  light  of  the  circumstances under which they were made, not
misleading; and (v) the Company's reasonable determination that a post-effective
amendment  to  the  registration statement would be appropriate, and the Company
shall  promptly make available to the Holder any such supplement or amendment to
the  related  prospectus.

     l.  Indemnification.  In  consideration  of  the  Holder's  execution  and
         ----------------
delivery  of  this Agreement and the Debenture Registration Rights Agreement and
acquiring the Debentures hereunder and in addition to all of the Company's other
obligations  under the Transaction Documents, the Company shall defend, protect,
indemnify  and  hold  harmless the Holder and all of its shareholders, officers,
directors,  employees  and direct or indirect investors and any of the foregoing
person's  agents  or other representatives (including, without limitation, those
retained  in  connection  with  the transactions contemplated by this Agreement)
(collectively,  the  "Indemnitees") from and against any and all actions, causes
of  action,  suits,  claims,  losses,  costs,  penalties,  fees, liabilities and
damages,  and expenses in connection therewith (irrespective of whether any such
Indemnitee  is  a  party  to  the  action for which indemnification hereunder is
sought),  and  including  reasonable  attorneys'  fees  and  disbursements  (the
"Indemnified  Liabilities"),  incurred  by  any  Indemnitee  as  a result of, or
arising  out  of,  or  relating  to  (i)  any misrepresentation or breach of any
representation  or  warranty made by the Company in the Transaction Documents or
any  other  certificate,  instrument or document contemplated hereby or thereby,
(ii)  any  breach  of  any  covenant,  agreement  or  obligation  of the Company
contained  in  the Transaction Documents or any other certificate, instrument or
document  contemplated  hereby  or  thereby,  (iii) any cause of action, suit or
claim  brought  or made against such Indemnitee by a third party and arising out
of  or resulting from the execution, delivery, performance or enforcement of the
Transaction  Documents  or  any  other  certificate,  instrument  or  document
contemplated  hereby or thereby, (iv) any transaction financed or to be financed
in  whole  or in part, directly or indirectly, with the proceeds of the issuance
of  the  Debentures, (v) the status of the Holder as an investor in the Company,
except,  in  the  case  of  any of such clauses, insofar as any such Indemnified
Liability  was  attributable  to  gross  negligence,  willful  misconduct or any
illegal  activity  on  the  part of Holder and, in the case of clause, (v) only,
insofar  as  any  such  Indemnified  Liability  was  attributable  to  an untrue
statement,  alleged  untrue  statement,  omission  or  alleged  omission made in
reliance  upon  and  in  conformity  with  written  information furnished to the
Company  by  the  Holder which is specifically intended by the Holder for use in
the  preparation  of  any  Registration  Statement,  preliminary  prospectus  or
prospectus.  To  the extent that the foregoing undertaking by the Company may be
unenforceable for any reason, the Company shall make the maximum contribution to
the  payment  and  satisfaction  of each of the Indemnified Liabilities which is
permissible  under  applicable  law.  The  indemnity provisions contained herein
shall  be  in  addition  to any cause of action or similar rights the Holder may
have,  and  any liabilities to which the Holder may be subject.  Notwithstanding
the  foregoing,  the Company shall have no indemnification responsibility in the
event  Holder  fails  to timely notify the Company of a claim or potential claim
for  which  indemnification  is  sought,  but  only to the extent the Company is
prejudiced  thereby.  The Company shall have the right to control the defense of
any  such  claim  and the Holder shall not consent to any settlement of any such
claim  without  the  prior  written  consent  of the Company (which shall not be
unreasonably  withheld  or  delayed).  The  Holder shall provide indemnification
comparable  in  scope  and  coverage  to  the  Company and corresponding related
persons  in  respect  of  any  Indemnified  Liability  if  and  to  the  extent
attributable  to gross negligence, willful misconduct or any illegal activity on
the part of the Holder, and shall be obligated to reimburse the Company and such
persons  to  the  same  extent  as the Company's reimbursement obligations under
Section  4(m)  below.

     m.     Reimbursement.  If (i) the Holder, other than by reason of its gross
            -------------
negligence  or  willful  misconduct,  becomes  involved  in  any capacity in any
action,  proceeding  or investigation brought by any shareholder of the Company,
in  connection  with  or  as  a  result  of the consummation of the transactions
contemplated  by the Transaction Documents, or if the Holder is impleaded in any
such  action,  proceeding  or  investigation  by any person, or (ii) the Holder,
other  than by reason of its gross negligence or willful misconduct or by reason
of  its  trading  of  the  Common  Stock  in a manner that is  illegal under the
federal  securities  laws,  becomes  involved  in  any  capacity  in any action,
proceeding  or investigation brought by the SEC against or involving the Company
or  in  connection  with  or as a result of the consummation of the transactions
contemplated  by the Transaction Documents, or if the Holder is impleaded in any
such  action,  proceeding or investigation by any person, then in any such case,
the  Company  will  reimburse  the  Holder  for  its  reasonable legal and other
expenses  (including  the cost of any investigation and preparation) incurred in
connection  therewith,  as  such  expenses are incurred. In addition, other than
with  respect  to  any  matter in which the Holder is a named party, the Company
will  pay to the Holder the charges, as reasonably determined by the Holder. The
reimbursement obligations of the Company under this section shall be in addition
to  any  liability  which  the Company may otherwise have, shall extend upon the
same terms and conditions to any affiliates of Holder that are actually named in
such  action,  proceeding  or  investigation,  and  partners, directors, agents,
employees, attorneys, accountants, auditors and controlling persons (if any), as
the case may be, of Holder and any such affiliate, and shall be binding upon and
inure  to  the  benefit  of  any  successors of the Company, Holder and any such
affiliate  and  any  such  person.

     n.  Transfer  Agent.  The  Company  covenants and agrees that, in the event
         ----------------
that  the  Company's  agency  relationship  with  the  transfer  agent should be
terminated  for  any  reason  prior  to  the  Maturity  Date  (as defined in the
Debenture  Agreement),  the  Company  shall  immediately  appoint a new transfer
agent.

5.     OPINION  LETTER/BOARD  RESOLUTION
       ---------------------------------

     Prior  to or on the Closing Date the Company shall deliver to the Holder an
opinion  letter signed by counsel for the Company in the form attached hereto as
Exhibit  D.

     If  so requested by the Holder, the Company shall instruct counsel to write
a 144 opinion letter provided the necessary paperwork has been submitted and the
Exemption  applies  (as  defined  in the Debenture Agreement).  If the Company's
counsel  fails to provide a Rule 144 opinion letter in a timely manner, then the
Company  shall:  (a)  pay  the Investor's counsel to write said Rule 144 opinion
letter;  and  (b) instruct the designated transfer agent to accept and rely upon
the  Rule  144  Opinion  letter.  Also,  prior  to  or on the Closing Date,  the
Company  shall  deliver to the Holder a signed Board Resolution authorizing this
Offering,  which  shall  be  attached  hereto  as  Exhibit  F.

6.     DELIVERY  INSTRUCTIONS;  FEES
       -----------------------------

     The  Debentures  being purchased hereunder shall be delivered to the Holder
on  the  Closing  Date  at  which  time  funds  will be wired to the Company, as
described  herein,  and  the Debentures will be delivered to the Holder, per the
Holder's  instructions.

7.     UNDERSTANDINGS.
       --------------

     The  Holder  understands,  acknowledges  and  agrees  as  follows:

     a.     No  U.S.  federal  or  state  agency  or  any  agency  of  any other
jurisdiction  has  made  any  finding or determination as to the fairness of the
terms  of  the  Offering for investment nor any recommendation or endorsement of
the  Debentures  or  the  Company.

     b.     The representations, warranties and agreements of the Holder and the
Company  contained  herein shall be true and correct in all material respects on
and  as  of  the date of the sale of the Debentures as if made on and as of such
date and shall survive the execution and delivery of this Subscription Agreement
and  the  purchase  of  the  Debentures.

     c.     In  making  an investment decision, the Holder is relying on its own
examination  of  the Company and the terms of the Offering, including the merits
and  risks involved.  The securities being sold hereby have not been recommended
by  any  federal  or  state  securities  commission  or  regulatory  authority.
Furthermore,  the  foregoing  authorities  have  not  confirmed  the accuracy or
determined the adequacy of this document.  Any representation to the contrary is
a  criminal  offense.

     d.     The Offering is intended to be exempt from registration by virtue of
Section  4(2)  of  the  1933  Act and the provisions of Regulation D thereunder,
which  is  in  part  dependent  upon the truth, completeness and accuracy of the
statements  made  by  the  undersigned  herein  and  in  the  Questionnaire.

     e.     It  is  understood  that  in  order not to jeopardize the Offering's
exempt  status  under  Section 4(2) of the 1933 Act and Regulation D, the Holder
may,  at a minimum, be required to fulfill the investor suitability requirements
thereunder.

     f.     The  shares  may  not  be  resold  except  as  permitted  under  the
securities act and applicable state securities laws, pursuant to registration or
exemption  therefrom.  Holder should be aware that they will be required to bear
the  financial  risks  of  this  investment  for  an  indefinite period of time.

8.     DISPUTES  SUBJECT  TO  ARBITRATION  GOVERNED  BY  MASSACHUSETTS  LAW.
       ---------------------------------------------------------------------

     a.     All  disputes  arising under this agreement shall be governed by and
interpreted  in  accordance  with the laws of the Commonwealth of Massachusetts,
without regard to principles of conflict of laws.  The parties to this agreement
will  submit all disputes arising under this agreement to arbitration in Boston,
Massachusetts before a single arbitrator of the American Arbitration Association
("AAA").  The  arbitrator  shall  be selected by application of the rules of the
AAA, or by mutual agreement of the parties, except that such arbitrator shall be
an  attorney  admitted to practice law in the Commonwealth of Massachusetts.  No
party  to  this agreement will challenge the jurisdiction or venue provisions as
provided  in  this section.  Nothing in Section 8 shall limit the Holder's right
to  seek  and  obtain an injunction for violation of the terms and conditions of
this  Agreement.  Any  injunction obtained shall remain in full force and effect
until  the arbitrator, as set forth in section 8, fully adjudicates the dispute.

9.     MISCELLANEOUS.
       -------------

     a.     Any  notices,  consents, waivers or other communications required or
permitted  to be given under the terms of this Subscription Agreement must be in
writing  and  will  be  deemed  to  have  been  delivered (i) upon receipt, when
delivered  personally;  (ii)  upon  receipt,  when sent by facsimile (provided a
confirmation  of  transmission  is  mechanically or electronically generated and
kept  on  file  by the sending party); or (iii) one (1) day after deposit with a
nationally  recognized  overnight  delivery  service,  in  each  case  properly
addressed to the party to receive the same.  The addresses and facsimile numbers
for  such  communications  shall  be:

If  to  the  Company:

Paul  Roman
SimplaGene  USA,  Inc,
500  Bi-County  Blvd.  Ste.  400
Farmingdale,  NY  11735-3940
Telephone:  631-694-1111
Facsimile:  631-694-8493

With  copy  to:

Gary  T.  Moomjian
Moomjian  &  Waite,  LLP
100  Jericho  Quadrangle  -  Suite  225
Jericho,  New  York  11753
Phone:  516-937-5900,  Ext.  47
Fax:  516-937-5050

If  to  the  Holder:

     At  the  address  listed  in  the  Questionnaire.

     Each  party  shall provide five (5) business days prior notice to the other
party  of  any  change  in  address,  phone  number  or  facsimile  number.

     a.     All  pronouns and any variations thereof used herein shall be deemed
to  refer  to  the  masculine,  feminine, impersonal, singular or plural, as the
identity  of  the  person  or  persons  may  require.

     b.     Neither  this  Subscription Agreement nor any provision hereof shall
be  waived,  modified,  changed,  discharged,  terminated,  revoked or canceled,
except  by  an  instrument  in  writing  signed  by the party effecting the same
against  whom  any  change,  discharge  or  termination  is  sought.

     c.     Intentionally  Omitted.

     d.     This  Subscription  Agreement  shall  be  enforced,  governed  and
construed  in  all  respects  in accordance with the laws of the Commonwealth of
Massachusetts,  as  such  laws are applied by Massachusetts courts to agreements
entered  into, and to be performed in, Massachusetts by and between residents of
Massachusetts,  and  shall  be  binding  upon the undersigned, the undersigned's
heirs,  estate  and  legal representatives and shall inure to the benefit of the
Company  and its successors.  If any provision of this Subscription Agreement is
invalid  or  unenforceable under any applicable statue or rule of law, then such
provisions  shall  be  deemed  inoperative  to  the  extent that it may conflict
therewith  and  shall be deemed modified to conform with such statute or rule of
law.  Any provision hereof that may prove invalid or unenforceable under any law
shall  not  affect the validity or enforceability of any other provision hereof.

     e.     This  Agreement  shall  not  be  assignable.

     f.     This  Subscription  Agreement, together with Exhibits A, B, C, D, E,
F,  G  and  H  attached  hereto  and  made  a part hereof, constitute the entire
agreement  between  the parties hereto with respect to the subject matter hereof
and  may  be  amended  only  by  a  writing  executed  by  both  parties hereto.

     g.     This  Subscription  Agreement  may  be  executed  in  two  or  more
counterparts,  all  of  which  taken  together  shall constitute one instrument.
Execution  and  delivery of this Subscription Agreement by exchange of facsimile
copies  bearing  the facsimile signature of a party shall constitute a valid and
binding  execution  and  delivery  of this Subscription Agreement by such party.
Such  facsimile  copies  shall  constitute  enforceable  original  documents.

     h.     When  in  this  Agreement or the Transaction Documents, reference is
made  to  any  party,  such reference shall be deemed to include the successors,
assigns,  heirs  and  legal  representatives of such party.  No party hereto may
transfer  any  rights  under this Agreement or the Transaction Documents, unless
the  transferee  agrees  to  be  bound  by, and comply with all of the terms and
provision  of  this  Agreement  and the Transaction Documents, as if an original
signatory  hereto  on  the  date  hereof.

10.  INTENTIONALLY  OMITTED.

11.  WAIVER.

     The  Holder's  delay  or  failure at any time or times hereafter to require
strict performance by Company of any undertakings, agreements or covenants shall
not  waiver, affect, or diminish any right of the Holder under this Agreement to
demand  strict  compliance and performance herewith. Any waiver by the Holder of
any  Event  of  Default  shall  not  waive or affect any other Event of Default,
whether  such Event of Default is prior or subsequent thereto and whether of the
same  or a different type. None of the undertakings, agreements and covenants of
the  Company  contained  in  this  Agreement,  and no Event of Default, shall be
deemed  to  have  been  waived by the Holder, nor may this Agreement be amended,
changed  or  modified,  unless such waiver, amendment, change or modification is
evidenced  by an instrument in writing specifying such waiver, amendment, change
or  modification  and  signed  by  the  Holder.

12.  NO  ORAL  AGREEMENTS

     THIS WRITTEN AGREEMENT AND THE ACCOMPANYING TRANSACTION DOCUMENTS REPRESENT
THE  FINAL  AGREEEMENTS  BETWEEN  THE  COMPANY  AND  THE  HOLDER  AND MAY NOT BE
CONTRADICTED  BY  EVIDENCE  OF  PRIOR,  CONTEMPORANEOUS,  OR  SUBSEQUENT  ORAL
AGREEMENTS  OF  THE  PARTIES;  THERE  ARE NO UNWRITTEN ORAL AGREEMENTS AMONG THE
PARTIES.

          [BALANCE  OF  PAGE  INTENTIONALLY  LEFT  BLANK)

<PAGE>

SimplaGene  USA,  Inc.
----------------------

QUESTIONNAIRE

     The information contained in this Questionnaire is being furnished in order
to  determine  whether the undersigned's subscription to purchase the Debentures
described  in  the  Subscription  Agreement  may  be  accepted.

     ALL  INFORMATION  CONTAINED  IN  THIS  QUESTIONNAIRE  WILL  BE  TREATED
CONFIDENTIALLY.  The  undersigned  understands,  however,  that  the Company may
present  this  Questionnaire  to  such parties as it deems appropriate if called
upon  to  establish that the proposed offer and sale of the Securities is exempt
from  registration  under  the  1933  Act, as amended.  Further, the undersigned
understands  that  the offering is required to be reported to the Securities and
Exchange  Commission, and to various state securities and "blue sky" regulators.

     IN ADDITION TO SIGNING THE SIGNATURE PAGE, IF REQUESTED BY THE COMPANY, THE
UNDERSIGNED  MUST  COMPLETE  FORM  W-9.

I.     PLEASE  CHECK  EACH  OF  THE  STATEMENTS  BELOW  THAT  APPLIES.

          1.     The  undersigned: (a) has total assets in excess of $5,000,000;
(b) was not formed for the specific purpose of acquiring the securities; and (c)
has  its  principal  place  of  business  in  ___________.

          2.     The undersigned is a natural person whose individual net worth*
or  joint  net  worth  with  his  or  her  spouse  exceeds  $1,000,000.

          3.     The  undersigned  is  a  natural  person  who had an individual
income*  in  excess  of  $200,000  in  each of the two most recent years and who
reasonably  expects  an  individual  income in excess of $200,000 in the current
year.  Such  income is solely that of the undersigned and excludes the income of
the  undersigned's  spouse.

          4.     The  undersigned  is a natural person who, together with his or
her  spouse, has had  a  joint income* in excess of $300,000 in each of  the two
most  recent  years  and  who  reasonably  expects  a  joint income in excess of
$300,000  in  the  current  year.

*     For  purposes of this Questionnaire, the term "net worth" means the excess
of  total  assets  over total liabilities.  In determining "income", an investor
should  add  to  his  or  her  adjusted gross income any amounts attributable to
tax-exempt  income  received, losses claimed as a limited partner in any limited
partnership,  deductions  claimed  for  depletion, contributions to IRA or Keogh
retirement  plan, alimony payments and any amount by which income from long-term
capital  gains  has  been  reduced  in  arriving  at  adjusted  gross  income.

               5.     The  undersigned  is:

     (a)     a  bank  as  defined  in  Section  3(a)(2)  of  the  1933  Act;  or

     (b)     a  savings  and loan association or other institution as defined in
Section 3(a)(5)(A) of the 1933 Act whether acting in its individual or fiduciary
capacity;  or

     (c)     a  broker  or  dealer registered pursuant to Section 15 of the 1934
Act;  or

     (d)     an  insurance  company as defined in Section 2(13) of the 1933 Act;
or

     (e)     An  investment  company registered under the Investment Company Act
of  1940 or a business development company as defined in Section 2(a)(48) of the
Investment  Company  Act  of  1940;  or

     (f)     a  small  business  investment  company  licensed by the U.S. Small
Business  Administration  under  Section  301  (c)  or (d) of the Small Business
Investment  Act  of  1958;  or

X          6.     The undersigned is an entity in which all of the equity owners
are  accredited  investors.

<PAGE>
II.     HOLDER  INFORMATION.

     Name  of  Entity  ___Dutchess  Private  Equities  Fund,  L.P.  and Dutchess
                          ------------------------------------------------------
Private  Equities  Fund,  II,  L.P._
------------------------------------

Person's  Name  Douglas  Leighton  Title: Managing  Member
                -----------------         ----------------

     State  of  Organization  ____Delaware___________________
                                  --------

     Principal  Business  Address  ___50  Commonwealth  Ave__

     City,  State,  Zip  Code  ______Boston,  MA  02116__________
                                     ------------------

     Taxpayer  Identification  Number  _PROVIDE____________________

      Phone  __617-301-4700________  Fax  ___617-249-0947___
               ------------                  ------------

     Send  Correspondence  to:
     ____________50  Commonweatlh  Ave,  Suite  2__________
     ____________Boston,  MA  02116________________________
     ______________________________________________________

<PAGE>

                              SimplaGene USA, Inc.
                             ----------------------

SIGNATURE  PAGE
---------------

     Your  signature on this Signature Page evidences your agreement to be bound
by  the  Questionnaire,  Subscription  Agreement,  Debenture Agreement, Warrant,
Security  Agreement  and  Debenture  Registration  Rights  Agreement.

     1.     The undersigned hereby represents that (a) the information contained
in  the  Questionnaire  is  complete  and  accurate and (b) the undersigned will
notify  the Company immediately if any material change in any of the information
           --------
occurs  prior  to  the  acceptance  of  the  undersigned's subscription and will
promptly  send  the  Companywritten  confirmation  of  such  change.
                     -------

     2.     The  undersigned signatory hereby certifies that he/she has read and
understands  the  Subscription  Agreement  and  Questionnaire,  and  the
representations  made  by  the  undersigned  in  the  Subscription Agreement and
Questionnaire  are  true  and  accurate.

           $2,500,000                         July 14,  2006
______________________________          ________________________
Amount  of  Debentures  being  purchased           Date

Dutchess  Private  Equities  Fund,  LP
Dutchess  Private  Equities  Fund  II,  LP

     By:  /s/Douglas  H.  Leighton
          ------------------------
                (Signature)

Name:     Douglas  H.  Leighton
----------------------------------------------
         (Please  Type  or  Print)

Title:  Managing  Member,
Dutchess  Capital  Management,  LLC;
General  Partner  to:
Dutchess  Private  Equities Fund, LP  and
Dutchess Private Equities Fund  II, LP
----------------------------------------------
            (Please  Type  or  Print)

COMPANY  ACCEPTANCE  PAGE
-------------------------

This  Subscription  Agreement  accepted  and  agreed
to  this  5th  day  of  July,  2006.

By  SimplaGene  USA,  Inc. and duly authorized to sign on behalf of the Company:
--------------------------

By: /s/Paul  Roman
    --------------
Paul  Roman,  President  &  Chief  Executive  Officer

By: /s/Thomas  McNeill
    ------------------
Thomas  McNeill,  Vice  President  &  Chief  Financial  Officer

<PAGE>

LIST  OF  EXHIBITS
-----------------

EXHIBIT  A               Notice  of  Conversion
EXHIBIT  B               Debenture  Registration  Rights  Agreement
EXHIBIT  C               Debenture  Agreement
EXHIBIT  D               Opinion  of  Company's  Counsel
EXHIBIT  E               Board  Resolution
EXHIBIT  G               Warrant
EXHIBIT  H               Security  Agreement

LIST  OF  SCHEDULES
-----------------

Schedule  3(a)     Subsidiaries
Schedule  3(c)     Capitalization
Schedule  3(e)     Conflicts
Schedule  3(g)     Material  Changes
Schedule  3(h)     Litigation
Schedule  3(l)     Intellectual  Property
Schedule  3(n)     Liens
Schedule  3(t)     Certain  Transactions

<PAGE>

                                    Exhibit A

                              NOTICE OF CONVERSION
                              --------------------

(To  be  Executed  by  the  Registered  Owner  in  order  to  Convert Debenture)
TO:  SIMPLAGENE  USA,  INC.
     The  undersigned  hereby  irrevocably  elects,  as  of ________________, to
convert  $________________  of  its convertible debenture (the "Debenture") into
Common Stock of SimplaGene USA, INC. (the "Company") according to the conditions
set  forth  in  the  Debenture  issued  by  the  Company.

Date  of  Conversion________________________________________________

Applicable  Conversion  Price________________________________________

Number  of  Common  Shares  Issuable upon this Conversion_______________________

Name(Print)________________________Dutchess_______________
                                   --------
Address______________50  Commonwealth  Ave,  Boston,  MA  02116_________
                     ------------------------------------------

Phone_____617-301-4700_____________  Fax________617-249-0947___________
          ------------                          ------------

                    By:_______________________________________

<PAGE>

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