Document:

EX-10.10

 Exhibit 10.10 

THIS PROMISSORY NOTE (“NOTE”) HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”). THIS NOTE HAS
BEEN ACQUIRED FOR INVESTMENT ONLY AND MAY NOT BE SOLD, TRANSFERRED OR ASSIGNED IN THE ABSENCE OF REGISTRATION OF THE RESALE THEREOF UNDER THE SECURITIES ACT OR AN OPINION OF COUNSEL REASONABLY SATISFACTORY IN FORM, SCOPE AND SUBSTANCE TO THE COMPANY
THAT SUCH REGISTRATION IS NOT REQUIRED. 
 PROMISSORY NOTE 
  

			
	Principal Amount: $100,000	  	Dated as of September 2, 2015

 Pace Holdings Corp. (f/k/a Paceline Holdings Corp.), a Cayman Islands exempted company (the
“Maker”), promises to pay to the order of TPACE Sponsor Corp. or its registered assigns or successors in interest (the “Payee”), or order, the principal sum of One Hundred Thousand Dollars ($100,000), plus any
increases thereto to reflect one or more additional loans that may be made from time to time by the Payee to the Maker in lawful money of the United States of America, on the terms and conditions described below. All payments on this Note shall be
made by check or wire transfer of immediately available funds or as otherwise determined by the Maker to such account as the Payee may from time to time designate by written notice in accordance with the provisions of this Note. 

1. Principal. The principal balance of Note shall be payable on the earlier of: (i) December 31, 2015, or (ii) the date on which Maker
consummates an initial public offering of its securities. The principal balance may be prepaid at any time. 
 2. Interest. No interest shall
accrue on the unpaid principal balance of this Note. 
 3. Application of Payments. All payments shall be applied first to payment in full of
any costs incurred in the collection of any sum due under this Note, including (without limitation) reasonable attorney’s fees, then to the payment in full of any late charges and finally to the reduction of the unpaid principal balance of this
Note. 
 4. Events of Default. The following shall constitute an event of default (“Event of Default”): 

(a) Failure to Make Required Payments. Failure by Maker to pay the principal amount due pursuant to this Note within five (5) business
days of the date specified above. 
 (b) Voluntary Bankruptcy, Etc. The commencement by Maker of a voluntary case under any applicable
bankruptcy, insolvency, reorganization, rehabilitation or other similar law, or the consent by it to the appointment of or taking possession by a receiver, liquidator, assignee, trustee, custodian, sequestrator (or other similar official) of Maker
or for any substantial part of its property, or the making by it of any assignment for the benefit of creditors, or the failure of Maker generally to pay its debts as such debts become due, or the taking of corporate action by Maker in furtherance
of any of the foregoing. 
 (c) Involuntary Bankruptcy, Etc. The entry of a decree or order for relief by a court having jurisdiction
in the premises in respect of Maker in an involuntary case under any applicable bankruptcy, insolvency or other similar law, or appointing a receiver, liquidator, assignee, custodian, trustee, sequestrator (or similar official) of Maker or for any
substantial part of its property, or ordering the winding-up or liquidation of its affairs, and the continuance of any such decree or order unstayed and in effect for a period of 60 consecutive days. 

 5. Remedies. 

(a) Upon the occurrence of an Event of Default specified in Section 4(a) hereof, Payee may, by written notice to Maker, declare this Note to be
due immediately and payable, whereupon the unpaid principal amount of this Note, and all other amounts payable thereunder, shall become immediately due and payable without presentment, demand, protest or other notice of any kind, all of which are
hereby expressly waived, anything contained herein or in the documents evidencing the same to the contrary notwithstanding. 
 (b) Upon the
occurrence of an Event of Default specified in Sections 4(b) and 4(c), the unpaid principal balance of this Note, and all other sums payable with regard to this Note, shall automatically and immediately become due and payable, in all cases without
any action on the part of Payee. 
 6. Waivers. Maker and all endorsers and guarantors of, and sureties for, this Note waive presentment for
payment, demand, notice of dishonor, protest, and notice of protest with regard to the Note, all errors, defects and imperfections in any proceedings instituted by Payee under the terms of this Note, and all benefits that might accrue to Maker by
virtue of any present or future laws exempting any property, real or personal, or any part of the proceeds arising from any sale of any such property, from attachment, levy or sale under execution, or providing for any stay of execution, exemption
from civil process, or extension of time for payment; and Maker agrees that any real estate that may be levied upon pursuant to a judgment obtained by virtue hereof, on any writ of execution issued hereon, may be sold upon any such writ in whole or
in part in any order desired by Payee. 
 7. Unconditional Liability. Maker hereby waives all notices in connection with the delivery,
acceptance, performance, default, or enforcement of the payment of this Note, and agrees that its liability shall be unconditional, without regard to the liability of any other party, and shall not be affected in any manner by any indulgence,
extension of time, renewal, waiver or modification granted or consented to by Payee, and consents to any and all extensions of time, renewals, waivers, or modifications that may be granted by Payee with respect to the payment or other provisions of
this Note, and agrees that additional makers, endorsers, guarantors, or sureties may become parties hereto without notice to Maker or affecting Maker’s liability hereunder. 

8. Notices. All notices, statements or other documents which are required or contemplated by this Agreement shall be: (i) in writing and
delivered personally or sent by first class registered or certified mail, overnight courier service or facsimile or electronic transmission to the address designated in writing, (ii) by facsimile to the number most recently provided to such party or
such other address or fax number as may be designated in writing by such party and (iii) by electronic mail, to the electronic mail address most recently provided to such party or such other electronic mail address as may be designated in writing by
such party. Any notice or other communication so transmitted shall be deemed to have been given on the day of delivery, if delivered personally, on the business day following receipt of written confirmation, if sent by facsimile or electronic
transmission, one (1) business day after delivery to an overnight courier service or five (5) days after mailing if sent by mail. 
 9.
Construction. THIS NOTE SHALL BE CONSTRUED AND ENFORCED IN ACCORDANCE WITH THE LAWS OF TEXAS, WITHOUT REGARD TO CONFLICT OF LAW PROVISIONS THEREOF. 

10. Severability. Any provision contained in this Note which is prohibited or unenforceable in any jurisdiction shall, as to such jurisdiction,
be ineffective to the extent of such prohibition or unenforceability without invalidating the remaining provisions hereof, and any such prohibition or unenforceability in any jurisdiction shall not invalidate or render unenforceable such provision
in any other jurisdiction. 

  
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 11. Trust Waiver. Notwithstanding anything herein to the contrary, the Payee hereby waives any and
all right, title, interest or claim of any kind (“Claim”) in or to any distribution of or from the trust account to be established in which the proceeds of the initial public offering (the “IPO”) conducted by the
Maker (including the deferred underwriters discounts and commissions) and the proceeds of the sale of the warrants issued in a private placement to occur prior to the effectiveness of the IPO are to be deposited, as described in greater detail in
the registration statement and prospectus to be filed with the Securities and Exchange Commission in connection with the IPO, and hereby agrees not to seek recourse, reimbursement, payment or satisfaction for any Claim against the trust account for
any reason whatsoever. 
 12. Amendment; Waiver. Any amendment hereto or waiver of any provision hereof may be made with, and only with, the
written consent of the Maker and the Payee. 
 13. Assignment. No assignment or transfer of this Note or any rights or obligations hereunder
may be made by any party hereto (by operation of law or otherwise) without the prior written consent of the other party hereto and any attempted assignment without the required consent shall be void. 

[Signature page follows] 

  
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 IN WITNESS WHEREOF, Maker, intending to be legally bound hereby, has caused this Note to
be duly executed by the undersigned as of the day and year first above written. 
  

					
	PACE HOLDINGS CORP. f/k/a Paceline Holdings Corp.
		
	By:	 	 /s/ Karl Peterson

		 	Name:	 	Karl Peterson
		 	Title:	 	President and Chief Executive Officer

  
 4EXHIBIT 10.21

 

DELMAR PHARMACEUTICALS, INC.

AUDIT COMMITTEE CHARTER

 

A. Purpose and Scope

 

The primary function of the Audit Committee (the "Committee")
is to oversee the accounting and financial reporting processes of DelMar Pharmaceuticals, Inc. (the "Corporation"), and
the audits of the financial statements of the Corporation and to exercise the responsibilities and duties set forth below, including,
but not limited to: (a) assist the Board of Directors in fulfilling its responsibilities by reviewing: (i) the financial reports
provided by the Corporation to the Securities and Exchange Commission ("SEC"), the Corporation's stockholders or to the
general public, and (ii) the Corporation's internal financial and accounting controls, (b) oversee the appointment, compensation,
retention and oversight of the work performed by any independent public accountants engaged by the Corporation, (c) recommend,
establish and monitor procedures designed to improve the quality and reliability of the disclosure of the Corporation's financial
condition and results of operations, (d) recommend, establish and monitor procedures designed to facilitate (i) the receipt, retention
and treatment of complaints relating to accounting, internal accounting controls or auditing matters and (ii) the receipt of confidential,
anonymous submissions by employees of concerns regarding questionable accounting or auditing matters, (e) engage advisors as necessary,
and (f) determine the funding from the Corporation that is necessary or appropriate to carry out the Committee's duties.

 

B. Composition

 

The Committee shall be comprised of such minimum number of directors
as to satisfy the audit committee composition requirements promulgated by the SEC, the Financial Industry Regulatory Authority,
any exchange upon which securities of the Corporation are traded, or any governmental or regulatory body exercising authority over
the Corporation (each a "Regulatory Body" and collectively, the "Regulatory Bodies"), as in effect from time
to time. The composition of the Committee shall satisfy the independence requirements of any applicable Regulatory Body, and each
member of the Committee shall be free from any relationship that, in the opinion of the Board of Directors, would interfere with
the exercise of his or her independent judgment as a member of the Committee.

 

Each member of the Committee shall be able to read and understand
fundamental financial statements, including a balance sheet, income statement, and cash flow statement, and not have participated
in the preparation of the financial statements of the Corporation or any current subsidiary of the Corporation at any time during
the past three years. At least one member of the Committee shall have had past employment experience in finance or accounting,
requisite professional certification in accounting, or other comparable experience or background which results in the individual's
financial sophistication, including being or having been a chief executive officer, chief financial officer or other senior officer
with financial oversight responsibilities.

 

    	 

    	 

    

 

The members of the Committee shall be elected by the Board of Directors
at the meeting of the Board of Directors following each annual meeting of stockholders and shall serve until their successors shall
be duly elected and qualified or until their earlier resignation or removal. Unless a Chair is elected by the full Board of Directors,
the members of the Committee may designate a Chair by majority vote of the full Committee membership.

 

The Committee shall meet with management, the internal auditors,
if any, and the independent accounting firm in executive sessions at least quarterly to discuss matters for which the Committee
has responsibility.

 

C. Responsibilities and Duties

 

To fulfill its responsibilities and duties, the Committee shall:

 

Document Review

 

1. Review and assess the adequacy of this Charter periodically as
conditions dictate, but at least annually (and update this Charter if and when appropriate).

 

2. Review with representatives of management and representatives
of the independent accounting firm the Corporation's audited annual financial statements prior to their filing as part of the Annual
Report on Form 10-K. After such review and discussion, the Committee shall recommend to the Board of Directors whether such audited
financial statements should be published in the Corporation's Annual Report on Form 10-K. The Committee shall also review the Corporation's
quarterly financial statements prior to their inclusion in the Corporation's Quarterly Reports on Form 10-Q.

 

3. Instruct the independent accounting firm to review the Corporation's
interim financial statements prior to their inclusion in the Corporation's Quarterly Reports on Form 10-Q.

 

Independent Accounting Firm

 

4. The Committee shall be directly responsible for the appointment,
compensation, retention and oversight of the work of any independent accounting firm engaged by the Corporation for the purpose
of preparing or issuing an audit report or performing other audit, review or attest services or any other related work.

 

The authority of the Committee shall include ultimate authority
to approve all audit engagement fees and terms. The Committee shall have the ultimate authority and responsibility to appoint,
evaluate and, when warranted, replace, such independent accounting firm (or to recommend such replacement for shareholder approval
in any proxy statement).

 

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5. Resolve any disagreements between management and the independent
accounting firm as to financial reporting matters.

 

6. Instruct the independent accounting firm that it should report
directly to the Committee on matters pertaining to the work performed during its engagement and on matters required by applicable
Regulatory Body rules and regulations.

 

7. On an annual basis, receive from the independent accounting firm
a formal written statement identifying all relationships between the independent accounting firm and the Corporation consistent
with Independence Standards Board Standard 1, as it may be modified or supplemented. The Committee shall actively engage in a dialogue
with the independent accounting firm as to any disclosed relationships or services that may impact the independent accounting firm's
objectivity and independence. The Committee shall take appropriate action to oversee the independence of the independent accounting
firm.

 

8. On an annual basis, discuss with representatives of the independent
accounting firm the matters required to be discussed by Statement on Auditing Standards 61, as it may be modified or supplemented.

 

9. Meet with the independent accounting firm prior to the audit
to review the planning and staffing of the audit and consider whether or not to approve the auditing services proposed to be provided.

 

10. Evaluate the performance of the independent accounting firm
and consider the discharge of the independent accounting firm when circumstances warrant. The independent accounting firm shall
be ultimately accountable to the Committee.

 

11. Oversee the rotation of the lead (or coordinating) audit partner
having primary responsibility for the audit and the audit partner responsible for reviewing the audit at least once every five
years, and oversee the rotation of other audit partners, in accordance with applicable rules and regulations.

 

12. Consider in advance whether or not to approve any audit and
non-audit services to be performed by the independent accounting firm required to be approved by the Committee pursuant to the
rules and regulations of any applicable Regulatory Body and adopt and implement policies for such pre-approval.

 

13. The Committee shall have the authority to oversee and determine
the compensation of any independent accounting firm engaged by the Corporation and shall notify the Corporation of anticipated
funding needs of the Committee.

 

Financial Reporting Processes

 

14. In consultation with the independent accounting firm and management,
review annually the adequacy of the Corporation's internal control over financial reporting.

 

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15. Review disclosures made to the Committee by the Corporation's
chief executive officer and chief financial officer in connection with their certifications of the Corporation's Annual Reports
on Form 10-K and Quarterly Reports on Form 10-Q, including disclosures concerning (a) evaluations of the design and operation of
the Corporation's internal control over financial reporting, (b) significant deficiencies and material weaknesses in the design
and operation of the Corporation's internal control over financial reporting which are reasonably likely to adversely affect the
Corporation's ability to record, process, summarize, and report financial information, and (c) any fraud, whether or not material,
that involves management or other employees who have a significant role in the Corporation's internal controls. The Committee shall
direct the actions to be taken and/or make recommendations to the Board of Directors of actions to be taken to the extent such
disclosures indicate the finding of any significant deficiencies in internal controls or fraud.

 

16. Regularly review the Company's critical accounting policies
and accounting estimates resulting from the application of these policies and inquire at least annually of both the Corporation's
internal auditors, if any, and the independent accounting firm as to whether either has any concerns relative to the quality or
aggressiveness of management's accounting policies.

 

17. Request and review periodic reports from management of the Corporation
as to the Corporation's processes for reporting on internal controls of the Corporation as required by Section 404 of the Sarbanes-Oxley
Act of 2002.

 

Compliance

 

18. To the extent deemed necessary by the Committee to carry out
its duties, it shall have the authority to engage outside counsel, independent accounting consultants and/or other experts at the
Corporation's expense.

 

19. Determine the funding necessary for (i) compensation of any
independent accounting firm engaged for the purpose of preparing or issuing an audit report or performing other audit, review or
attest services for the Corporation, (ii) ordinary administrative expenses of the Committee that are necessary or appropriate in
carrying out the Committee's duties, and (iii) compensation of any outside advisors to be engaged by the Committee and notify the
Corporation of anticipated funding needs of the Committee.

 

20. Establish written procedures for (a) the receipt, retention,
and treatment of complaints received by the Corporation regarding accounting, internal accounting controls, or auditing matters;
and (b) the confidential, anonymous submission by employees of the Corporation of concerns regarding questionable accounting or
auditing matters.

 

21. Investigate any allegations that any officer or director of
the Corporation, or any other person acting under the direction of any such person, took any action to fraudulently influence,
coerce, manipulate, or mislead any independent public or certified accountant engaged in the performance of an audit of the financial
statements of the Corporation for the purpose of rendering such financial statements materially misleading and, if such allegations
prove to be correct, take or recommend to the Board of Directors appropriate disciplinary action.

 

Reporting

 

22. Prepare, in accordance with the rules of the SEC, as modified
or supplemented from time to time, a written report of the Committee to be included in the Corporation's annual proxy statement
for each annual meeting of stockholders.

 

23. To the extent required by any Regulatory Body, instruct the
Corporation's management to disclose in its annual proxy statement for each annual meeting of stockholders, Annual Report on Form
10-K and Quarterly Report on Form 10-Q, the approval by the Committee of any non-audit services performed by the independent accounting
firm, and review the substance of any such disclosure and the considerations relating to the compatibility of such services with
maintaining the independence of the accounting firm.

 

While the Audit Committee has the responsibilities and powers set
forth in this Charter, it is not the duty of the Audit Committee to plan or conduct audits or to determine that the Corporation's
financial statements are complete and accurate and are in accordance with generally accepted accounting principles.

 

 

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