Document:

icnb_ex101.htm

EXHIBIT 10.1
 
MARKETING AND DISTRIBUTION AGREEMENT
 
by and between
 
ICONIC BRANDS, INC. 
 
and 
 
UNITED SPIRITS, INC.
 
This marketing and distribution agreement (this “Agreement”), dated as of April 1, 2019 (the “Effective Date”) is between Iconic Brands, Inc., a Nevada corporation (“Iconic”) and United Spirits, Inc., a New York corporation (“United”) for the distribution of alcoholic products described herein. Iconic and United are each a “Party” and collectively, the “Parties”. 
 
WHEREAS, HI Limited Partnership (“Hooters”) owns or controls certain trademarks for the “Hooters” restaurant and products, including USPTO Trade Marks associated with the serial numbers 88062395, 88023053, 87681938, 87681891, 85961933, 85869984 (collectively, the “Hooters Marks”); and 
 
WHEREAS, United holds a license (the “Hooters License”) from HI Limited Partnership to market and sell certain alcoholic products utilizing the Hooters Marks (the “Products”) in a territory which includes the United States, Europe and Asia as set forth in the Hooters License (the “Territory”); and
 
WHEREAS, Iconic is a publicly traded, national company with experience in the marketing and distribution of alcoholic and non-alcoholic beverages; and
 
WHEREAS, the Parties wish to enter into this Agreement for Iconic to market and assist in the distribution of the Products.
 
HOW, THEREFORE, for the mutual promises and covenants contained herein and other valuable consideration, the sufficiency of which is expressly acknowledged, the Parties agree as follows:
 
A. TERM
 
1. The term of this Agreement (the “Term”) shall be for a period of five years beginning from the Effective date, unless extended or terminated pursuant to the terms set forth herein.
 
2. The Term may be extended by up to five years by Iconic upon written notice to United, so long as Iconic is not in breach of this Agreement.
 
Iconic Brands, Inc. and United Spirits, Inc.
Marketing and Distribution Agreement
April 1, 2019
Page 1 of 5
 
	 
	 
	
 
	 

 
3. This Agreement shall terminate upon the occurrence of any of the following:
 
a. Termination of the Hooters License;
 
b. A Party is in breach of any term of the Agreement and has failed to cure such breach upon 30 day’s prior written notice from the non-breaching Party; or
 
c. A Party becomes insolvent, a receiver is appointed over its assets or it is the subject of a bankruptcy or similar insolvency proceeding.
 
B. MARKETING AND DISTRIBUTION 
 
4. United grants Iconic the exclusive right to market and distribute Product in the Territory on its behalf.
 
5. Iconic shall use its best efforts to market the Products for sale to (a) “Hooters” branded restaurants; (b) liquor distributors; and (c) off-premise, retail establishments (with all sales being made through distributors licensed to conduct business in the state of such sale).
 
6. Iconic shall insure all Product merchandising and sales shall conform with Hooters License.
 
7. United shall act as the licensed wholesaler for the Product.
 
8. Iconic does not acquire any ownership rights to the Hooters Trademarks or the Hooters License under this Agreement other than the marketing and distribution rights set forth herein.
 
9. Iconic shall comply with all reasonable instructions from United as to requirements for the use, protection and maintenance of the Hooters Trademarks. Iconic shall do nothing, and shall not permit any action, that will diminish or adversely affect Hooters interests in the Hooters Trademarks or United’s rights under the Hooters License.
 
C. INVOICING AND COMPENSATION
 
10. United shall receive one dollar ($1.00) per case of Product sold to any wholesaler for retail distribution. 
 
11. Iconic shall be responsible for invoicing and collecting payments on all sales. 
 
12. Iconic shall be responsible for all expenses relating to the product, including payment of royalties due under the Hooters License pursuant to its terms.
 
Iconic Brands, Inc. and United Spirits, Inc.
Marketing and Distribution Agreement
April 1, 2019
Page 2 of 5
 
	 
	 
	
 
	 

 
D. OWNERSHIP OF PRODUCT
 
13. All product purchased from its manufacturer shall remain the property of United until title transfers to the distributor or other purchaser or recipient (as may be allowed by law). Iconic shall never hold title to or take possession of any Product.
 
E. COMPLIANCE WITH LAWS
 
14. During the term of this Agreement, United shall obtain and maintain in good standing, or otherwise have valid access to, all state and federal licenses required for the performance of this Agreement, including all licenses for the importation of the Product into the Territory.
 
15. During the term of this Agreement, Iconic shall comply with all federal and state laws with respect to the marketing and distribution of the Product.
 
F. GOVERNING LAW
 
16. This Agreement shall be construed under the laws of the State of New York without giving effect to the principals of conflicts of laws that would require the substantive or procedural law of any other jurisdiction. 
 
17. The Parties hereby consent to the exclusive personal jurisdiction and venue of the state and federal courts located in the Eastern District of New York. 
 
G. NOTICE
 
18. Notices shall be sent to the following addresses:
 
If to Iconic:
 
Iconic Brands, Inc.
44 Seabro Avenue
Amityville New York 11701
Attn: Richard DeCicco
Richard,decicco@gmail.com
 
If to United:
 
United Spirits, Inc.
44 Seabro Avenue
Amityville New York 11701
Attn: Richard DeCicco
Richard,decicco@gmail.com
 
Iconic Brands, Inc. and United Spirits, Inc.
Marketing and Distribution Agreement April 1, 2019
Page 3 of 5
 
	 
	 
	
 
	 

 
19. All notices given under this Agreement shall be effective three business days after being mailed, the following business day when sent via overnight courier or the business day when sent via electronic mail.
 
20. Either Party may change its notice address upon written notice to the other Party.
 
H. SAVINGS CLAUSE
 
21. If any term or provision of this Agreement is determined to be invalid or unenforceable, such term or provision shall be modified so as to enforceable in a manner that effectuates the intent of the Parties.
 
I. NON-TRANSFERABILITY; BINDING EFFECT
 
22. This Agreement may not be transferred by either Party without the written consent of the other.
 
23. This Agreement shall be binding upon and inure to the benefit of the Parties, their successors and permitted assigns. 
 
J. ENTIRE AGREEMENT; COUNTERPARTS
 
24. This Agreement embodies all of the understandings and material terms for the agreement between the Parties with respect to the transaction contemplated hereby. 
 
25. This Agreement supersedes all prior discussions, negotiations and agreements between the Parties concerning the subject matter of the Agreement.
 
26. This Agreement may only be amended by a writing executed by both parties.
 
27. This Agreement may be executed in multiple counterparts and transmitted electronically, with all parts, taken together, constituting one agreement.
 
[Signature Page Follows]
 
Iconic Brands, Inc. and United Spirits, Inc.
Marketing and Distribution Agreement
April 1, 2019
Page 4 of 5
 
	 
	 
	
 
	 

 
IN WITNESS WHEREOF, with the intent of being bound by its terms, the Parties have caused their authorized agents to execute this Agreement as of the date first written above.
 
	United Spirits, Inc.
	 

	 
	 

	By: 
	/s/ Richard DeCicco 
	 

	 
	Richard DeCicco
	 

	 
	President
	 

	 
	 
	 

	Iconic Brands, Inc.
	 

		 

	By: 
	/s/ Richard DeCicco 
	
	 
	Richard DeCicco

	 
	President

 
Iconic Brands, Inc. and United Spirits, Inc.
Marketing and Distribution Agreement
April 1, 2019
Page 5 of 5Exhibit 4.2

 

Execution
Version

 

ABBOTT
IRELAND FINANCING DAC

SUPPLEMENTAL INDENTURE NO. 2

 

€590,000,000 0.100% Notes due 2024

 €590,000,000 0.375% Notes due 2027

 

THIS SUPPLEMENTAL INDENTURE
NO. 2, dated as of November 19, 2019 (this “Supplemental Indenture”), among ABBOTT IRELAND FINANCING DAC, an
Irish designated activity company (herein called the “Company,” which term includes any successor Person under
the Indenture hereinafter referred to), ABBOTT LABORATORIES, an Illinois corporation (the “Parent Guarantor,”
which term includes any successor Person under the Indenture hereinafter referred to) and U.S. BANK NATIONAL ASSOCIATION, a national
banking association, as trustee (the “Trustee,” which term includes any successor trustee under the Indenture
hereinafter referred to) and ELAVON FINANCIAL SERVICES DAC, as paying agent, transfer agent and registrar (the “Paying
Agent”, the “Transfer Agent” and the “Security Registrar”, respectively).

 

RECITALS OF THE COMPANY:

 

WHEREAS, the Company
and the Parent Guarantor have heretofore executed and delivered to the Trustee an Indenture, dated as of September 27, 2018 (the
 “Base Indenture”, and the Base Indenture as supplemented or amended from time to time, including by this Supplemental
Indenture, the “Indenture”), providing for the issuance from time to time of one or more series of Securities
(as defined in the Base Indenture);

 

WHEREAS, the Company
has duly determined to appoint the Paying Agent as the paying agent and the Transfer Agent and Security Registrar as the transfer
agent and registrar, each under the Agency Agreement, dated as of the date hereof (“Agency Agreement”), and
the Paying Agent, the Transfer Agent and the Security Registrar are willing to accept such appointment with respect to the Notes;

 

WHEREAS, Article Nine
of the Indenture provides for various matters with respect to any series of Securities issued under the Indenture to be established
in an indenture supplemental to the Indenture;

 

WHEREAS, Section 9.1(7)
of the Indenture provides that the Company, the Parent Guarantor and the Trustee may enter into an indenture supplemental to the
Indenture to establish the form or terms of Securities of any series as permitted by Sections 2.1 and 3.1 of the Indenture; and

 

WHEREAS, all the conditions
and requirements necessary to make this Supplemental Indenture, when duly executed and delivered, a valid and binding agreement
in accordance with its terms and for the purposes herein expressed, have been performed and fulfilled.

  

     

     

    

 

NOW THEREFORE, THIS
SUPPLEMENTAL INDENTURE WITNESSETH:

 

For and in consideration
of the premises and the issuance of the series of Securities and Guarantee provided for herein, the parties hereto hereby covenant
and agree for the equal and proportionate benefit of the respective Holders of the Securities of each such series as follows:

 

Article
I

RELATION TO INDENTURE; DEFINITIONS; RULES OF CONSTRUCTION

 

Section
1.1           Relation
to Indenture. This Supplemental Indenture constitutes an integral part of the Indenture.

 

Section
1.2           Relation to Agency Agreement. The terms of this Supplemental Indenture are subject to the terms of the Agency
Agreement which shall be deemed incorporated herein. In the event of an inconsistency between the terms of the Indenture, this
Supplemental Indenture and the Agency Agreement, the terms of the Agency Agreement shall prevail, except that the rights, benefits,
protections, indemnities and immunities of the Trustee shall be governed by the Indenture.

 

Section
1.3           Definitions. For all purposes of this Supplemental Indenture, the following terms shall have the respective
meanings set forth in this Section.

 

“2024 Notes”
has the meaning specified in Section 2.1.

 

“2027 Notes”
has the meaning specified in Section 2.1.

 

“Business
Day” means, unless otherwise expressly specified, any day, other than a Saturday or Sunday on which (i) banking institutions
and foreign exchange markets are open for general business in the City of New York, the City of London, the City of Dublin and
the City of Zurich and (ii) the Trans-European Automated Real-Time Gross Settlement Express Transfer system (“TARGET2
System”), or any successor thereto, operates.

 

“Certificated
Note” means a Note in definitive registered form that does not include the Global Notes Legend and in a customary form
agreed by the Company, the Parent Guarantor, the Trustee and the Paying Agent.

 

“Clearstream,
Luxembourg” means Clearstream Banking S.A.

 

“Common Depositary”
means any Person acting as the common depositary for Euroclear and Clearstream, Luxembourg, which initially shall be Elavon Financial
Services DAC.

 

“Comparable
Government Bond” means, in relation to any Comparable Government Bond Rate calculation, at the discretion of an Independent
Investment Banker, a bond that is a direct obligation of the Federal Republic of Germany (“German government bond”),
whose maturity is closest to the Par Call Date of the Notes of the series to be redeemed, or if the Independent Investment Banker
in its discretion determines that such similar bond is not in issue, such other German government bond as the Independent Investment
Banker may, with the advice of the Reference Bond Dealers, determine to be appropriate for determining the Comparable Government
Bond Rate.

 

    -2-

     

    

 

“Comparable
Government Bond Rate” means the price, expressed as a percentage (rounded to three decimal places, with 0.0005 being
rounded upwards), at which the gross redemption yield on the Notes of the series to be redeemed, if they were to be purchased at
such price on the third TARGET2 System Day prior to the Redemption Date, would be equal to the gross redemption yield on such TARGET2
System Day of the Comparable Government Bond on the basis of the middle market price of the Comparable Government Bond prevailing
at 11:00 a.m. (Central European time) on such TARGET2 System Day as determined by an Independent Investment Banker in its discretion.

 

“Corporate
Trust Office of the Paying Agent and Transfer Agent” means, initially, the office of Elavon Financial Services DAC located
at Building 8, Block E, Cherrywood Business Park, Loughlinstown, Co. Dublin, Ireland.

 

“Corporate
Trust Office of the Security Registrar” means, initially, the office of Elavon Financial Services DAC located at Building
8, Block E, Cherrywood Business Park, Loughlinstown, Co. Dublin, Ireland.

 

“euro”
or “€” means the single currency introduced at the third stage of the European Monetary Union pursuant
to the Treaty establishing the European Community, as amended.

 

“Euroclear”
means Euroclear Bank SA/NV.

 

“Global Notes
Legend” means the legend set forth in Exhibits A1 and A2 to this Supplemental Indenture, as applicable.

 

“Independent
Investment Banker” means one of the Reference Bond Dealers that the Company appoints to act as the Independent Investment
Banker from time to time.

 

“Notes”
means the 2024 Notes and the 2027 Notes.

 

“Par Call
Date” means (i) with respect to the 2024 Notes, October 19, 2024 (one month prior to the Stated Maturity of the 2024
Notes) and (ii) with respect to the 2027 Notes, August 19, 2027 (three months prior to the Stated Maturity of the 2027 Notes).

 

“Reference
Bond Dealer” means four firms that are brokers of, and/or market makers in, German government bonds (each a “Primary
Bond Dealer”), which firms the Company specifies from time to time; provided, however, that if any of them ceases to
be a Primary Bond Dealer, the Company shall substitute another Primary Bond Dealer therefor.

 

“TARGET2 System
Day” means any day on which the TARGET2 System, or any successor thereto, operates.

 

“U.S. Dollar”
or “$” means the currency of the United States of America.

  

    -3-

     

    

 

Section
1.4           Amendments to the Base Indenture solely with respect to the Notes.

 

(a)          Solely
with respect to the Notes, Section 1.1 of the Base Indenture shall be amended by deleting the definition of “Principal Domestic
Property” and replacing such definition with the following:

 

“Principal
Domestic Property” means any building, structure or other facility, together with the land upon which it is erected and
fixtures comprising a part thereof, used primarily for manufacturing, processing, research, warehousing or distribution and located
in the United States of America (excluding its territories and possessions and Puerto Rico), owned or leased by the Parent Guarantor
or any Domestic Subsidiary and having a net book value which, on the date the determination as to whether a property is a Principal
Domestic Property is being made, exceeds 2% of Consolidated Net Assets of the Parent Guarantor, other than any such building, structure
or other facility or a portion thereof (i) which is an air or water pollution control facility financed by State or local governmental
obligations, or (ii) which the Chairman of the Board, the Chief Executive Officer, an Executive Vice President, a Senior Vice President
or a Vice President, and the Chief Financial Officer, the Treasurer, or an Assistant Treasurer, of the Parent Guarantor determine
in good faith, at any time on or prior to such date, is not of material importance to the total business conducted, or assets owned,
by the Parent Guarantor and its Subsidiaries as an entirety.

 

(b)          Solely
with respect to the Notes, Section 4.1(1) of the Base Indenture shall be amended by inserting the following directly after the
term “as the case may be” is first used: “ (provided
that in connection with any discharge relating to any redemption that requires the payment of a premium, the amount deposited
shall be sufficient for purposes of the Indenture to the extent that an amount is deposited with the Trustee equal to the premium
calculated as of the date of the notice of redemption, with any deficit as of the Redemption Date only required to be deposited
with the Trustee on or prior to the Redemption Date)”.

 

(c)          Solely
with respect to the Notes, Section 8.1(1) of the Base Indenture shall be amended by inserting the word “Republic”
directly before the words “of Ireland”.

 

(d)          Solely
with respect to the Notes, Section 10.6 of the Base Indenture shall be amended and restated, and superseded, in its entirety by
the following:

 

“(i) The Company
shall not itself, and shall not permit any of its Subsidiaries to, create or permit to subsist any Mortgage upon the whole or any
part of its present or future assets or revenues (including uncalled capital) to secure any indebtedness for borrowed money which
is represented by any bond, note, debenture, debenture stock, loan stock, certificate or other instrument which is (with the consent
of the issuer of the indebtedness) at the time listed, quoted or traded on any stock exchange or in any securities market (including,
without limitation, any over-the-counter market), or to secure any guarantee of any such indebtedness of any other Person and (ii)
the Company shall not permit any of its Subsidiaries to guarantee any such indebtedness of any other Person without (a) in
the case of the creation of a Mortgage, at the same time or prior thereto, securing the Notes equally and ratably therewith, or,
in the case of any such guarantee, promptly guaranteeing the Notes on a pari passu basis therewith or (b) in each case, providing
such other security interest or other arrangement (whether or not it includes the granting of a security interest or provision
of a guarantee) for the Notes of any series as may be approved by Holders of a majority in principal amount of outstanding Notes
of such series.

 

    -4-

     

    

 

The Parent Guarantor
will not itself, and it will not permit any Domestic Subsidiary to, incur, issue, assume or guarantee any indebtedness for borrowed
money represented by notes, bonds, debentures or other similar evidences of indebtedness for borrowed money (such notes, bonds,
debentures or other similar evidences of indebtedness for borrowed money being hereinafter in this Article called “Debt”),
secured by a Mortgage on any Principal Domestic Property, or any shares of stock or Debt of any Domestic Subsidiary, without effectively
providing or causing its Domestic Subsidiary to provide that the Guarantee of the Parent Guarantor is secured equally and ratably
with (or prior to) such secured Debt, so long as such Debt is so secured, unless, after giving effect thereto, the aggregate amount
of all such secured Debt plus all Attributable Debt in respect of Sale and Leaseback Transactions involving Principal Domestic
Properties (other than Sale and Leaseback Transactions permitted pursuant to clause (2) of Section 10.7) would not
exceed 15% of Consolidated Net Assets. This Section shall not apply to, and there shall be excluded from secured Debt in any computation
under this Section, Debt secured by:

 

(1)          Mortgages
on property of, or on any shares of stock or Debt of, any Person existing at the time such Person becomes a Domestic Subsidiary;

 

(2)          Mortgages in favor of the Parent Guarantor or any Subsidiary thereof;

 

(3)          Mortgages
in favor of the United States of America or any State thereof, or any department, agency or instrumentality or political subdivision
of the United States of America or any State thereof, or in favor of any other country, or any department, agency or instrumentality
or political subdivision thereof, to secure partial, progress, advance or other payments pursuant to any contract or statute;

 

(4)          Mortgages on property, shares of stock or Debt existing at the time of acquisition thereof (including acquisition through
merger or consolidation);

 

(5)          Mortgages
to secure the payment of all or any part of the cost of acquisition, construction, development or improvement of the underlying
property, or to secure debt incurred to provide funds for any such purpose, provided that the commitment of the creditor
to extend the credit secured by any such Mortgage is obtained not later than 365 days after the later of (a) the completion of
the acquisition, construction, development or improvement of such property or (b) the placing in operation of such property;

 

(6)          with
respect to each series of the Notes, Mortgages existing on the first date on which a Note of such series is authenticated by the
Trustee hereunder;

 

(7)          Mortgages incurred in connection with pollution control, industrial revenue or similar financings;

 

(8)          Mortgages
created in substitution of or as replacements for any Mortgages referred to in the foregoing clauses (1) through (7),
inclusive; provided, that, based on a good faith determination of an Officer of the Parent Guarantor, the property encumbered
under any such substitute or replacement Mortgage is substantially similar in nature to the property encumbered by the otherwise
permitted Mortgage which is being replaced; and

 

    -5-

     

    

 

(9)           any
extension, renewal or replacement (or successive extensions, renewals or replacements), as a whole or in part, of any Debt secured
by any Mortgage referred to in the foregoing clauses (1) through (8), inclusive; provided, that (i) such
extension, renewal or replacement Mortgage is limited to all or a part of the same property, shares of stock or Debt that secured
the Mortgage so extended, renewed or replaced (plus improvements on such property, and plus any property relating to a specific
project, the completion of which is funded pursuant to clause (ii)(b) below) and (ii) the Debt secured by such Mortgage
at such time is not increased (other than (a) by an amount equal to any related financing costs (including, but not limited to,
the accrued interest and premium, if any, on the Debt being refinanced) and (b) where an additional principal amount of Debt is
incurred to provide funds for the completion of a specific project that is subject to a Mortgage securing the Debt being extended,
refinanced or renewed, by an amount equal to such additional principal amount).”

 

(e)           Solely with respect to the Notes, Section 10.7 of the Base Indenture shall be amended and restated, and superseded,
in its entirety by the following:

 

“The Parent Guarantor
will not itself, and it will not permit any Domestic Subsidiary to, enter into any Sale and Leaseback Transaction, unless either:

 

(1)           the Parent Guarantor or such Domestic Subsidiary could incur Debt secured by a Mortgage on the Principal Domestic Property
to be leased back pursuant to Section 10.6 in an amount equal to the Attributable Debt with respect to such Sale and Leaseback
Transaction without equally and ratably securing the Guarantee of the Parent Guarantor; or

 

(2)           the
Parent Guarantor, within 180 days after the sale or transfer shall have been made by the Parent Guarantor or by any such Domestic
Subsidiary, applies to the retirement of the Parent Guarantor’s Funded Debt, an amount equal to the greater of: (i) the
net proceeds of the sale of the Principal Domestic Property sold and leased back pursuant to such arrangement or (ii) the fair
market value of the Principal Domestic Property so sold and leased back at the time of entering into such arrangements (as determined
by any two of the following: the Chairman of the Board, the Chief Executive Officer, an Executive Vice President, a Senior Vice
President or a Vice President, and the Chief Financial Officer, the Treasurer or an Assistant Treasurer, of the Parent Guarantor);
provided, that the amount to be applied to the retirement of Funded Debt shall be reduced by (a) the principal amount of any Securities
of any series issued under the Indenture delivered within 180 days after such sale to the Trustee for retirement and cancellation,
and (b) the principal amount of such Funded Debt, other than Securities of any series issued under the Indenture, voluntarily
retired by the Parent Guarantor within 180 days after such sale. Notwithstanding the foregoing, no retirement referred to in this
clause (2) may be effected by payment at maturity or pursuant to any mandatory sinking fund payment or any mandatory prepayment
provision.”

 

    -6-

     

    

 

(f)            Solely with respect to the Notes, Section 13.3 of the Base Indenture shall be amended and restated, and superseded,
in its entirety by the following:

 

“Upon the
Company’s exercise of the above option applicable to this Section, the Company shall be released from its obligations under
Sections 8.1, each Guarantor shall be released from its obligations under Section 14.4, and each of the Company and the Parent
Guarantor shall be released from its obligations under Sections 10.6 and 10.7 (and any covenant applicable to such Securities or
Guarantee that are determined pursuant to Section 3.1 to be subject to this provision), and the occurrence of an event specified
in Section 5.1(4) (with respect to any of Sections 8.1, 10.6, 10.7 or 14.4) (and any other Event of Default applicable to such
Securities or Guarantee that are determined pursuant to Section 3.1 to be subject to this provision) shall not be deemed to be
an Event of Default with respect to the Outstanding Securities of such series on and after the date the conditions set forth below
are satisfied (hereinafter, “covenant defeasance”). For this purpose, such covenant defeasance means that, with respect
to the Outstanding Securities of such series, the Company or the applicable Guarantor, as the case may be, may omit to comply with
and shall have no liability in respect of any term, condition or limitation set forth in any such Section or clause whether directly
or indirectly by reason of any reference elsewhere herein to any such Section or clause or by reason of any reference in any such
Section or clause to any other provision herein or in any other document, but the remainder of this Indenture and such Securities
shall be unaffected thereby”.

 

(g)           Solely
with respect to the Notes, the third sentence of clause (1) of Section 13.4 of the Base Indenture shall be deleted and replaced
with the following:

 

“For this
purpose, “Government Obligations” means euro denominated securities that are direct obligations (or certificates representing
an ownership interest in such obligations) of a member state of the European Union as of the original issue date of the Notes (including
any agency or instrumentality thereof) for the payment of which the full faith and credit of such government is pledged; provided
that such member state has a long-term government debt rating of “A1” or higher by Moody’s Investors Service,
Inc. (or any successor thereof) or “A+” or higher by S&P Global Ratings, a division of S&P Global Inc., or
any successor to its rating agency business, or the equivalent rating category of another internationally recognized rating agency.”

 

(h)           Solely
with respect to the Notes, Section 14.4(1) of the Base Indenture shall be amended by deleting the words “the due and punctual
payment of the principal of and any premium and interest (including all Additional Amounts, if any, payable pursuant to Section
10.9) on all the Securities and the performance or observance of every obligation of this Indenture and the Securities on the
part of a Guarantor to be performed or observed” and replacing them with the following: “the due and punctual payment
of all obligations on its Guarantee and the performance or observance of every obligation of this Indenture and its Guarantee
on the part of a Guarantor to be performed or observed”.

 

    -7-

     

    

 

(i)            Solely
with respect to the Notes, Section 14.4(3) of the Base Indenture shall be amended by deleting the words “to effectively
secure the Securities equally and ratably” and replacing them with the following: “to effectively secure its Guarantee
equally and ratably”.

 

Section
1.5            Rules of Construction. For all purposes of this Supplemental Indenture:

 

(a)           capitalized
terms used herein without definition shall have the meanings specified in the Base Indenture;

 

(b)           all
references herein to Articles and Sections, unless otherwise specified, refer to the corresponding Articles and Sections of this
Supplemental Indenture;

 

(c)           the
terms “herein,” “hereof,” “hereunder” and other words of similar import refer to this Supplemental
Indenture; and

 

(d)           in
the event of a conflict with the definition of terms in the Base Indenture, the definitions in this Supplemental Indenture shall
control.

 

Section
1.6           References.
References to the Security Register in the Indenture will be deemed to refer to the register of Holders of the Notes as prescribed
by this Supplemental Indenture, and the provisions of the Notes and references to the Security Registrar in the Indenture will
be deemed to refer to the Registrar as defined in the Agency Agreement and the Notes.

 

Article
II

THE SECURITIES

 

Section
2.1           Title
of the Notes. There will be (i) a series of Securities designated the 0.100% Notes due 2024 (the “2024 Notes”)
and (ii) a series of Securities designated the 0.375% Notes due 2027 (the “2027 Notes”).

 

Section
2.2           Initial Principal Amount and Stated Maturity. The 2024 Notes will be initially issued in an aggregate principal
amount of €590,000,000 and the 2027 Notes will be initially issued in an aggregate principal amount of €590,000,000.
The Stated Maturity of the 2024 Notes shall be November 19, 2024 and the Stated Maturity of the 2027 Notes shall be November 19,
2027.

 

Section
2.3           Holders
of the Notes. Title to the Notes will pass upon registration of transfer in accordance with Section 2.7. The Company, the
Parent Guarantor, the Trustee, the Paying Agent, the Transfer Agent and the Security Registrar will (except as otherwise required
by law) deem and treat the registered holder of any Note as the absolute owner thereof (whether or not it is overdue and regardless
of any notice of ownership, trust or other interest or any writing on, or the theft or loss of, such Note) for all purposes but,
in the case of any Global Note, without prejudice to the provisions set out in the next paragraph.

 

    -8-

     

    

 

For so long as the
Notes are represented by a Global Note deposited with, and registered in the name of a nominee for, a Common Depositary, each Person
(other than Euroclear or Clearstream, Luxembourg) who is for the time being shown in the records of Euroclear or of Clearstream,
Luxembourg as the holder of a particular nominal amount of the Notes (in which regard any certificate or other document issued
by Euroclear or Clearstream, Luxembourg as to the nominal amount of the Notes standing to the account of any Person shall be conclusive
and binding for all purposes save in the case of manifest error) shall upon their receipt of a certificate or other document as
aforesaid be treated by the Company, the Parent Guarantor, the Trustee, the Paying Agent, the Transfer Agent and the Security Registrar
as the holder of such nominal amount of the Notes and the registered holder of the Global Note shall be deemed not to be the holder
for all purposes other than with respect to the payment of principal or interest or any other amount on such nominal amount of
the Notes, for which purpose the registered holder of the Global Note shall be treated by the Company, the Parent Guarantor, the
Trustee, the Paying Agent, the Transfer Agent and the Security Registrar as the holder of such nominal amount of the Notes in accordance
with and subject to the terms of the Global Note and the expressions “Holder”, “Holder of Notes” and “Holder
of the Notes” and related expressions shall be construed accordingly.

 

Section
2.4            Interest. Interest on the 2024 Notes will be payable annually in arrear on November 19 of each year, commencing
on November 19, 2020 and interest on the 2027 Notes will be payable annually in arrear on November 19 of each year, commencing
on November 19, 2020 (each such date being an “Interest Payment Date”), to the Holders in whose names the Notes
are registered in the Security Register (which shall be held outside the United Kingdom) at (i) in the case of Notes represented
by a Global Note, the close of the Business Day (which, for these purposes, is a day on which Euroclear and Clearstream, Luxembourg
are open for business) immediately prior to the relevant Interest Payment Date and (ii) in all other cases, the close of business
at the registered office of the Paying Agent on the 15th day (or, if such 15th day is not a day on which banks are open for business
in the city where the specified office of the Security Registrar is located, the first such day prior to such 15th day) before
the relevant Interest Payment Date (in each case, a “Regular Record Date”). Interest on the Notes shall be computed
on the basis of the actual number of days in the period for which interest is being calculated, and including the last date on
which interest was paid or duly provided for in the Notes (or from November 19, 2019, if no interest has been paid on the Notes),
but excluding the next following Interest Payment Date. This payment convention is referred to as ACTUAL/ACTUAL (ICMA) (as defined
in the rulebook of the International Capital Market Association).

 

Section
2.5            Issuance in Euro. Initial Holders will be required to pay for the Notes in euro, and all payments of principal
of, and premium, if any, Additional Amounts, if any, and interest on, the Notes, including payments made upon redemption of the
Notes, shall be payable in euro. If the Company is unable to obtain euro in amounts sufficient to make a required payment under
the Notes due to the imposition of exchange controls or other circumstances beyond the Company’s control (including the dissolution
of the European Monetary Union) or if the euro is no longer being used by the then member states of the European Monetary Union
that have adopted the euro as their currency or for the settlement of transactions by public institutions or within the international
banking community, then all payments in respect of the Notes shall be made in U.S. Dollars until the euro is again available to
the Company or so used. In such circumstances, the amount payable on any date in euro shall be converted into U.S. Dollars at the
rate mandated by the Board of Governors of the Federal Reserve System as of the close of business in the City of New York on the
second Business Day prior to the relevant payment date, or in the event the Board of Governors of the Federal Reserve System has
not mandated a rate of conversion, on the basis of the most recent U.S. Dollar/euro exchange rate published in The Wall Street
Journal on or prior to the second Business Day in the City of New York prior to the relevant payment date or, in the event The
Wall Street Journal has not published such exchange rate, the rate will be determined in the Company’s sole discretion on
the basis of the most recently available market exchange rate for euro. Any payment in respect of the Notes so made in U.S. Dollars
will not constitute an Event of Default. Neither the Trustee nor the Paying Agent shall be responsible for obtaining exchange rates,
effecting conversions or otherwise handling redenominations.

 

    -9-

     

    

 

Section
2.6            Form and Dating.

 

(a)          General. The Notes shall initially be issued in the form of one or more global notes in fully registered,
book-entry form (“Global Notes”), duly executed by the Company and authenticated by the Trustee, which shall
be deposited with the Common Depositary and shall be registered in the name of USB Nominees (UK) Limited, as nominee of the Common
Depositary. The Notes shall be in substantially the forms of Exhibits A1 and A2 attached hereto. The Notes may have
notations, legends or endorsements required by law, stock exchange rule or usage. Each Note shall be dated the date of its authentication.
The Notes shall be issued in fully registered form only in denominations of €100,000 and integral multiples of €1,000
in excess thereof. The Notes of each series and any additional Notes of such series subsequently issued under the Indenture may
be consolidated and form a single series with an existing series of the Notes and have the same terms as to status, redemption
or otherwise as such series of Notes (except for the amount and/or date of the first payment of interest thereon, the offering
price, the issue date and/or the date from which interest starts to accrue thereon), provided, however, that if any such additional
Notes are not fungible with the Notes of the applicable series for U.S. federal income tax purposes, such additional Notes will
have a separate ISIN number.

 

The terms and provisions
contained in the Notes shall constitute, and are hereby expressly made, a part of this Supplemental Indenture, and the Company,
the Parent Guarantor, the Trustee, the Paying Agent, the Transfer Agent and the Security Registrar, by their execution and delivery
of this Supplemental Indenture, expressly agree to such terms and provisions and to be bound thereby. However, to the extent any
provision of any Note conflicts with the express provisions of this Supplemental Indenture, the provisions of this Supplemental
Indenture shall govern and be controlling.

 

(b)          Book-Entry
Provisions. This Section 2.6(b) shall apply only to a Global Note deposited with the Common Depositary. The Company and the
Parent Guarantor shall execute and the Trustee shall, in accordance with this Section 2.6(b) and pursuant to a Company Order,
authenticate and deliver initially one or more Global Notes that (a) shall be registered in the name of USB Nominees (UK) Limited,
as nominee of the Common Depositary for such Global Note or Global Notes and (b) shall be delivered by the Trustee to such Common
Depositary.

 

(c)          Payment.

 

Payments of principal
with respect to Notes may be made at the office or agency maintained for such purpose in Dublin (initially the Corporate Trust
Office of the Paying Agent and Transfer Agent), provided that, in the case of Certificated Notes, all such payments of principal
on the Notes for which the Holders thereof have given wire transfer instructions, will be required to be made by wire transfer
of immediately available funds to the accounts specified by the Holders thereof. No service charge will be made for any registration
of transfer, but payment of a sum sufficient to cover any tax or governmental charge payable in connection with that registration
may be required.

 

    -10-

     

    

 

Payments of interest
with respect to Notes may be made at the office or agency maintained for such purpose in Dublin (initially the Corporate Trust
Office of the Paying Agent and Transfer Agent), provided that, in the case of Certificated Notes, all such payments of interest
on the Notes for which the Holders thereof have given wire transfer instructions, will be required to be made by wire transfer
of immediately available funds to the accounts specified by the Holders thereof. No service charge will be made for any registration
of transfer, but payment of a sum sufficient to cover any tax or governmental charge payable in connection with that registration
may be required.

 

If the principal of
or any premium or interest on the Notes is payable on a day that is not a Business Day, the required payment shall be made on the
following Business Day as if it were made on the date the payment was due and no interest shall accrue on the amount so payable
for the period from and after that Interest Payment Date, that maturity date or that Redemption Date, as the case may be, until
the next Business Day.

 

All payments of
any amounts paid to or the order of USB Nominees (UK) Limited, as nominee for the Common Depositary for Euroclear and Clearstream,
Luxembourg shall be valid and, to the extent of the sums so paid, effectual to satisfy and discharge the liability of the Company
for the moneys payable on the Notes.

 

(d)           Certificated
Notes. Except as provided in Section 2.7, owners of a beneficial interest in the Global Notes will not have Notes registered
in their names and will not receive physical delivery of Certificated Notes.

 

Section
2.7            Transfer and Exchange.

 

(a)           Transfer
and Exchange of Certificated Notes. When Certificated Notes are presented to the Security Registrar with a request:

 

(i)            to
register the transfer of such Certificated Notes; or

 

(ii)           to
exchange such Certificated Notes for an equal principal amount of Certificated Notes of other authorized denominations,

 

the Security Registrar shall
register the transfer or make the exchange as requested if its reasonable requirements for such transaction are met; provided,
however, that the Certificated Notes surrendered for transfer or exchange:

 

(A)          shall
be duly endorsed or accompanied by a written instrument of transfer in form reasonably satisfactory to the Company and the Security
Registrar, duly executed by the Holder thereof or his attorney duly authorized in writing; and

 

    -11-

     

    

 

 

(B)          
are accompanied by the following additional information and documents, as applicable:

 

(x)       if
such Certificated Notes are being delivered to the Security Registrar by a Holder for registration in the name of such Holder,
without transfer, a certification from such Holder to that effect (in the form set forth on the reverse side of the Note); or

 

(y)       if
such Certificated Notes are being transferred to the Company, a certification to that effect (in the form satisfactory to the Trustee).

 

(b)          
Restrictions on Transfer of a Certificated Note for a Beneficial Interest in a Global Note. A Certificated
Note may not be exchanged for a beneficial interest in a Global Note except upon satisfaction of the requirement set forth below.
Upon receipt by the Security Registrar of a Certificated Note, duly endorsed or accompanied by a written instrument of transfer
in form reasonably satisfactory to the Company and the Security Registrar, together with written instructions directing the Security
Registrar to make an adjustment on its books and records with respect to such Global Note to reflect an increase in the aggregate
principal amount of the Notes represented by the Global Note, such instructions to contain information regarding the Common Depositary
account to be credited with such increase, then the Security Registrar shall cancel such Certificated Note and cause the aggregate
principal amount of Notes represented by the Global Note to be increased by the aggregate principal amount of the Certificated
Note to be exchanged and shall credit or cause to be credited to the account of the Person specified in such instructions a beneficial
interest in the Global Note equal to the principal amount of the Certificated Note so canceled. If no Global Notes are then outstanding
and the Global Note has not been previously exchanged for certificated securities pursuant to Section 2.6, the Company shall issue
and the Trustee shall authenticate, upon receipt of a Company Order, a new Global Note in the appropriate principal amount.

 

(c)           
Exchange of Global Notes for Certificated Notes. Notwithstanding Section 3.5 of the Indenture, a Global Note
shall be exchanged by the Company for Certificated Notes only if:

 

(i)             Euroclear
or Clearstream, Luxembourg is closed for business for a continuous period of at least 14 days (other than by reason of legal holidays)
or announces an intention permanently to cease business;

 

(ii)            the
Company, at its option, notifies the Trustee, Security Registrar and Paying Agent in writing that it elects to cause the issuance
of Certificated Notes; or

 

(iii)          
an Event of Default has occurred and is continuing.

 

In the case
of clause (i) and (iii) above, the Holder of a Global Note (acting on behalf of one or more of the accountholders) or the Trustee
may give notice to the Company and, in the case of clause (ii) above, the Company may give notice to the Trustee, the Security
Registrar, the Paying Agent and the Holders of Notes, of its intention to exchange a Global Note for Certificated Notes on or after
the Exchange Date.

  

    -12-

     

    

 

On or after
the Exchange Date the Holder of the Global Note may, or in the case of clause (ii) above, shall surrender it to or to the order
of the Paying Agent. In exchange for the Global Note, the Company shall deliver, or procure the delivery of, an equal aggregate
principal amount of Certificated Notes. On exchange of the Global Note, the Company will procure that it is cancelled and, if the
Holder so requests, returned to the Holder together with any relevant Certificated Notes.

 

For these
purposes, “Exchange Date” means a day specified in the notice requiring exchange falling not less than 60 days
after the day on which the notice requiring exchange is given and being a day on which banks are open for general business in London,
in the place in which the specified office of the Paying Agent is located and, except in the case of exchange pursuant to (i) above,
in the place in which Euroclear and Clearstream, Luxembourg are located.

 

In all cases,
Certificated Notes delivered in exchange for any Global Note or beneficial interest therein will be registered in the names, and
issued in any approved denominations, requested by or on behalf of the Holder of the relevant Global Notes (in accordance with
its customary procedures).

 

The Company,
the Trustee, the Security Registrar, the Paying Agent and the Transfer Agent shall not be liable for any delay by the Holder of
the relevant Global Notes in identifying the Holders of beneficial interests in the Global Notes, and each such Person may conclusively
rely on, and will be protected in relying on, instructions from Euroclear or Clearstream, Luxembourg for all purposes (including
with respect to the registration and delivery, and the respective principal amounts, of the Certificated Notes to be issued).

 

(d)          
Obligations with Respect to Transfers and Exchanges of Notes.

 

(i)            To
permit registrations of transfers and exchanges, the Company and the Parent Guarantor shall execute and the Trustee shall authenticate
Certificated Notes and Global Notes at the Company’s request.

 

(ii)           No service charge shall be made for any registration of transfer or exchange of the Notes, but the Company or the
Security Registrar may require payment of a sum sufficient to cover any transfer tax, assessments, or similar governmental charge
payable in connection therewith (other than any such transfer taxes, assessments or similar governmental charge payable upon exchange
or transfer pursuant to Sections 9.5 or 11.7 of the Indenture).

 

(e)            Neither
the Company nor the Security Registrar shall be required to register the transfer of or exchange Notes of any series (i) during
a period beginning at the opening of business 15 days before the day of the mailing or, as the case may be, publication of a notice
of redemption of Notes of that series selected for redemption under Section 4.1 and ending at the close of business on the day
of such mailing or, as the case may be, publication, or (ii) so selected for redemption in whole or in part, except the unredeemed
portion of any Note being redeemed in part.

 

    -13-

     

    

 

(f)            All
Notes issued upon any transfer or exchange pursuant to the terms of this Supplemental Indenture shall evidence the same indebtedness
for borrowed money and shall be entitled to the same benefits under the Indenture as the Notes surrendered upon such transfer
or exchange.

 

(g)           No
Obligation of the Trustee.

 

(i)            The
Trustee shall have no responsibility or obligation to any beneficial owner of a Global Note, the Common Depositary or any other
Person with respect to the accuracy of the records of the Common Depositary or its nominee, with respect to any ownership interest
in the Notes or with respect to the delivery to any beneficial owner or other Person (other than the Common Depositary) of any
notice (including any notice of redemption or repurchase) or the payment of any amount, under or with respect to such Notes.

 

(ii)           The
Trustee shall have no obligation or duty to monitor, determine or inquire as to compliance with any restrictions on transfer imposed
under this Supplemental Indenture or under applicable law with respect to any transfer of any interest in any Note (including
any transfers between or among beneficial owners in any Global Note) other than to require delivery of such certificates and other
documentation or evidence as are expressly required by, and to do so if and when expressly required by, the terms of this Supplemental
Indenture, and to examine the same to determine substantial compliance as to form with the express requirements hereof.

 

Article
III

 

TRUSTEE AND PAYING AGENT

 

Section
3.1             Appointments.
The Paying Agent and Transfer Agent for the Notes shall initially be Elavon Financial Services DAC. The Company hereby initially
designates the Corporate Trust Office of the Paying Agent and Transfer Agent as the office to be maintained by it where Notes
may be presented for payment and transfer or exchange and where notices to or demands upon the Company in respect of the Notes
or the Indenture may be served. The Security Registrar for the Notes shall initially be Elavon Financial Services DAC and the
Company hereby initially designates the Corporate Trust Office of the Security Registrar as the office to be maintained by it
where Notes may be presented for registration of transfer or exchange. The Company may at any time vary or terminate the appointment
of the Paying Agent or Security Registrar to appoint additional or other paying agents or another security registrar and to approve
any change in the offices where they act; provided that there will, save where the Company delivers an Officer’s
Certificate to the Trustee stating that it is unduly onerous, at all times be a Paying Agent (as defined in the Base Indenture)
such that no obligation to withhold or deduct tax will arise in respect of payments on the Notes (whether held in global form
in a recognized clearing system or in certificated form) pursuant to Irish law. In furtherance of such appointment, the Trustee
is hereby authorized and directed to execute and deliver the Agency Agreement. The Trustee shall not be liable for any act or
omission of the Paying Agent, Security Registrar, Transfer Agent, Common Depositary, Euroclear or Clearstream, Luxembourg.

 

    -14-

     

    

 

Article
IV

 

REDEMPTION

 

Section
4.1             Optional
Redemption.

 

(a)           The
Company may redeem the Notes of any series at any time prior to the applicable Par Call Date in whole or in part, in each case
at the Company’s option, at a redemption price equal to the greater of:

 

(i)            100%
of the principal amount of the Notes of such series to be redeemed; and

 

(ii)           the
sum of the present values of the remaining scheduled payments (through the applicable Par Call Date with respect to the Notes
of such series assuming for such purpose that the Notes of such series matured on the applicable Par Call Date) of principal and
interest on the Notes of such series to be redeemed (exclusive of interest accrued to the Redemption Date) discounted to the Redemption
Date on an annual basis (ACTUAL/ACTUAL (ICMA)) at the applicable Comparable Government Bond Rate plus (A) with respect to the
2024 Notes, 15 basis points and (B) with respect to the 2027 Notes, 20 basis points.

 

In each case, the Company will
pay accrued and unpaid interest, if any, on the principal amount being redeemed to, but excluding, the Redemption Date.

 

(b)           In
addition, the Company may redeem the Notes of any series at any time on or after the applicable Par Call Date in whole or in part,
in each case at the Company’s option, at a redemption price equal to 100% of the principal amount of the Notes of such series
to be redeemed plus accrued and unpaid interest, if any, on the principal amount being redeemed to, but excluding, the Redemption
Date.

 

(c)           Notice
of redemption will be mailed (or delivered electronically) at least 15 but not more than 60 days before the Redemption Date (i)
in the case of Notes represented by a Global Note, to and through Euroclear or Clearstream, Luxembourg for communication by them
to the holders of interests in the Notes, or (ii) in the case of Certificated Notes, to each Holder of the Notes to be redeemed
at its registered address set out on the Security Registrar at the close of business at the registered office of the Paying Agent
on the 5th day (or, if such 5th day is not a day on which banks are open for business in the city where the specified office of
the Security Registrar is located, the first such day prior to such 5th day) before the issuance of the notice of redemption (in
each case, a “Relevant Record Date”).

 

(d)           In
the case of a partial redemption of Notes, the Notes to be redeemed (“Redeemed Notes”) will (a) in the case
of Redeemed Notes represented by Certificated Notes, be selected by the Trustee (or by the Security Registrar if other than the
Trustee) individually by lot not more than 10 days prior to the Redemption Date, and (b) in the case of Redeemed Notes represented
by a Global Note, be selected in accordance with the rules of Euroclear and/or Clearstream, Luxembourg (to be reflected in the
records of Euroclear and Clearstream, Luxembourg as either a pool factor or a reduction in nominal amount, at their discretion,
and in the records of the Trustee or its nominee as a decrease in the principal amount of such Global Note). In the case of Redeemed
Notes represented by Certificated Notes, a list of the serial numbers of such Redeemed Notes will be published not less than 7
days prior to the Redemption Date.

 

    -15-

     

    

 

Section
4.2            Redemption
for Tax Reasons. If, as a result of any change in, or amendment to, the laws (or any regulations or rulings promulgated under
the laws) of Ireland, the United States, the jurisdiction of residence for tax purposes of either the Company or the Parent Guarantor,
any jurisdiction from or through which payments are made by or on behalf of the Company or the Parent Guarantor, or, in each case,
any taxing authority thereof or therein (each a “Taxing Jurisdiction”) or any change in, or amendment to, an
official position or judicial precedent regarding the application or interpretation of such laws, regulations or rulings, which
change or amendment is announced or becomes effective on or after November 15, 2019 (or, the date such jurisdiction became a Taxing
Jurisdiction with respect to the Company or the Parent Guarantor, as applicable, if later), based upon a written opinion of independent
counsel selected by the Company or the Parent Guarantor, the Company or the Parent Guarantor has or will become obligated to pay
Additional Amounts as described in Article V hereunder with respect to the Notes of any series or under and pursuant to
the Guarantee of the Parent Guarantor, and such obligation cannot be avoided by the taking of reasonable measures, then the Company
may at any time at its option, on not less than 15 nor more than 60 days’ prior notice to Holders and provided that such
notice shall not be provided earlier than 90 days before the first date on which such Additional Amounts would be owed if a payment
on the Notes of such series were then due, redeem, in whole, but not in part, the notes of such series at a redemption price equal
to 100% of the principal amount of the Notes to be redeemed plus accrued and unpaid interest, if any, on the principal amount
being redeemed to, but excluding, the Redemption Date.

 

Notice of redemption
will be mailed (or delivered electronically) at least 15 but not more than 60 days before the Redemption Date (i) in the case of
Notes represented by a Global Note, to and through Euroclear or Clearstream, Luxembourg for communication by them to the holders
of interests in the Notes, or (ii) in the case of Certificated Notes, to each Holder of the Notes to be redeemed at its registered
address set out on the Security Registrar on the Relevant Record Date.

 

Article
V

 

PAYMENT OF ADDITIONAL AMOUNTS

 

Section
5.1            General.
All payments in respect of the Notes and under and pursuant to the Guarantee of the Parent Guarantor will be made by or on behalf
of the Company (or, if such Guarantee is called, the Parent Guarantor) without withholding or deduction for, or on account of,
any present or future tax, assessment or governmental charge, imposed or levied by a Taxing Jurisdiction, unless such withholding
or deduction is required by law. The Company or, as the case may be, the Parent Guarantor will pay as additional interest on each
series of the Notes such additional amounts (the “Additional Amounts”) as are necessary in order that the net
amount of the principal of, and premium, if any, and interest on such Notes received by a Holder after withholding or deduction
for any future tax, assessment or other governmental charge imposed by a Taxing Jurisdiction will not be less than the amount
provided in the Notes or, as the case may be, the amount due and payable under and pursuant to such Guarantee to such Holder to
be then due and payable; provided, however, that the foregoing obligation to pay Additional Amounts shall not apply:

 

    -16-

     

    

 

(a)           to any tax, assessment or other governmental charge that would not have been imposed but for the Holder (or the beneficial
owner for whose benefit such Holder holds such Note), or a fiduciary, settlor, beneficiary, member or shareholder of the Holder
if the Holder is an estate, trust, partnership or corporation, or a Person holding a power over an estate or trust administered
by a fiduciary holder, being considered as:

 

(i)            being
or having been engaged in a trade or business in the United States or having or having had a permanent establishment in the United
States;

 

(ii)           having a current or former connection with the United States (other than a connection arising solely as a result
of the ownership of the Notes, the receipt of any payment or the enforcement of any rights thereunder), including being or having
been a citizen or resident of the United States;

 

(iii)          being
or having been a personal holding company, a passive foreign investment company or a controlled foreign corporation for U.S. federal
income tax purposes, a foreign tax-exempt organization with respect to the United States or a foreign personal holding corporation
that has accumulated earnings to avoid U.S. federal income tax;

 

(iv)          failing
to qualify for the exemption from tax on “portfolio interest” by reason of Section 871(h)(3) or Section 881(c)(3)
of the U.S. Internal Revenue Code of 1986, as amended (the “Code”) or any successor provision or the related
Treasury Regulations (including the certification requirements); or

 

(v)           being
a bank receiving payments on an extension of credit made pursuant to a loan agreement entered into in the ordinary course of its
trade or business;

 

(b)          to any tax, assessment or other governmental charge that is imposed on a payment to a Holder that is not the sole
beneficial owner of the Notes, or a portion of the Notes, or that is a fiduciary, partnership or limited liability company, but
only to the extent that a beneficiary or settlor with respect to the fiduciary, a beneficial owner or member of the partnership
or limited liability company would not have been entitled to the payment of an Additional Amount had the beneficiary, settlor,
beneficial owner or member received directly its beneficial or distributive share of the payment;

 

(c)           to any tax, assessment or other governmental charge that would not have been imposed but for the failure of the Holder
or any other Person to comply with, upon request, certification, identification or information reporting requirements concerning
the nationality, residence, identity or connection with the United States of the Holder or beneficial owner of the Notes, if compliance
is required by statute, by regulation of the United States or any taxing authority therein or by an applicable income tax treaty
to which the United States is a party as a precondition to exemption from such tax, assessment or other governmental charge;

 

    -17-

     

    

  

(d)          to any tax, assessment or other governmental charge that is not imposed by way of withholding;

 

(e)          to any estate, inheritance, gift, sales, excise, transfer, wealth, capital gains or personal property tax or similar
tax, assessment or other governmental charge;

 

(f)           to any withholding or deduction that is imposed on a payment pursuant to Sections 1471 through 1474 of the Code and
related Treasury regulations, pronouncements relating thereto or official interpretations thereof or any successor provisions,
any agreements entered into pursuant to Section 1471(b)(1) of the Code, any applicable intergovernmental agreement entered into
between the United States and any other governmental authority in connection with the implementation of the foregoing and any regulations
or official law, agreement or interpretations thereof implementing an intergovernmental approach thereto;

 

(g)          any taxes that would not have been imposed, withheld, deducted or levied but for a change in any law, treaty, regulation
or administrative or judicial interpretation that becomes effective more than 30 days after the applicable payment becomes due
or is duly provided for, whichever occurs later; or

 

(h)          in
the case of any combination of items (a), (b), (c), (d), (e), (f) and (g).

 

Section
5.2           No Other Requirements. The Notes are subject in all cases to any tax, fiscal or other law or regulation or
administrative or judicial interpretation applicable to the Notes. Except as specifically provided under this Article V,
the Company shall not be required to make any payment for any tax, duty, assessment or governmental charge of whatever nature imposed
by any government or a political subdivision or taxing authority of or in any government or political subdivision.

 

Section
5.3           Definition.
As used in this Article V, the term “United States” means the United States of America (including the states and the
District of Columbia and any political subdivision thereof), and the term “U.S. person” means any individual who is
a citizen or resident of the United States for U.S. federal income tax purposes, a corporation, partnership or other entity created
or organized in or under the laws of the United States, any state of the United States or the District of Columbia, including
an entity treated as a corporation for United States income tax purposes, or any estate or trust the income of which is subject
to U.S. federal income taxation regardless of its source.

 

Article
VI

 

NOTICES 

 

Section
6.1           General.
Notwithstanding any other provisions of this Supplemental Indenture, all notices to the Holders will be valid if published in
a leading English language daily newspaper published in London or such other English language daily newspaper with general circulation
in Europe as the Company may decide. Any such notice will be deemed to have been given on the date of the first such publication.

 

    -18-

     

    

  

The Company shall also
ensure that notices are duly published in a manner which complies with the rules and regulations of any stock exchange or other
relevant authority on which the Notes are listed from time to time.

 

Notwithstanding the
above requirements of this Article VI relating to notices to Holders, for so long as all of the Notes are represented by a Global
Note and such Global Note is held on behalf of Euroclear and/or Clearstream, Luxembourg, notices to Holders may, instead, be given
by delivery of the relevant notice to Euroclear and/or Clearstream, Luxembourg (as the case may be) for communication to the relevant
accountholders provided that, so long as the Notes are listed on any stock exchange, the notices are duly published in a manner
which complies with the rules and regulations of any such stock exchange on which the Notes are listed from time to time. Any such
notice shall be deemed to have been given to the Holders on the date on which such notice is given to Euroclear and/or Clearstream,
Luxembourg (as the case may be) as aforesaid.

 

Notices to be given
by any Holder shall, unless otherwise set out in this Supplemental Indenture, be in writing and given by lodging the same with
the Paying Agent or the Transfer Agent or, if the Notes are represented by a Global Note and such Global Note is held on behalf
of Euroclear and/or Clearstream, Luxembourg, may be given through the clearing system in accordance with its standard rules and
procedures.

 

Article
VII

 

MISCELLANEOUS PROVISIONS

 

Section
7.1           Ratification.
The Base Indenture, as supplemented and amended by this Supplemental Indenture, is in all respects hereby adopted, ratified and
confirmed.

 

Section
7.2           Counterparts. This Supplemental Indenture may be executed in any number of counterparts, each of which when
so executed shall be deemed an original, and all such counterparts shall together constitute but one and the same instrument.

 

Section
7.3           Governing
Law. THIS SUPPLEMENTAL INDENTURE SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK.

 

Section
7.4           The
Trustee. The recitals contained herein and in the Notes and Guarantees, except the Trustee’s certificates of authentication,
shall be taken as the statements of the Company and the Parent Guarantor, as applicable, and the Trustee assumes no responsibility
for their correctness. The Trustee makes no representations as to and shall not be responsible for the validity or sufficiency
of this Supplemental Indenture or of the Notes or Guarantees.

 

[signature page follows]

 

    -19-

     

    

 

IN WITNESS WHEREOF,
the parties hereto have caused this Supplemental Indenture No. 2 to be duly executed as of the day and year first above written.

 

	 	ABBOTT IRELAND FINANCING DAC
	 	 
		By	/s/
                                         Karen Peterson
	 	 	Name:	 Karen Peterson
	 	 	Title:	Authorised Signatory

		

 

[Signature Page to Supplemental Indenture
No. 2]

 

    

     

    

 

 

	 	ABBOTT LABORATORIES
	 	 
		By:	/s/ Karen Peterson
	 	 	Name:	 Karen Peterson
	 	 	Title:	 Vice President and Treasurer

		
 

 

[Signature Page to Supplemental Indenture
No. 2]

 

    

     

    

 

 

	 	U.S.
                                         BANK NATIONAL ASSOCIATION,
 as
                                         Trustee
	 	 
		By:	/s/ Grace A. Gorka
	 	 	Name:	 Grace A. Gorka
	 	 	Title:	 Vice President

 

	 	ELAVON FINANCIAL SERVICES DAC,

 as Paying Agent, Transfer Agent and 

Security Registrar
	 	 
		By:	/s/ David Harnett
	 	 	Name:	 David Harnett
	 	 	Title:	 Authorised Signatory
	 	 	 
	 	By:	/s/ Michael
                                         Leong
	 	 	Name:	 Michael Leong
	 	 	Title:	Authorised Signatory

 

[Signature Page to Supplemental Indenture
No. 2]

 

     

     

    

 

 

EXHIBIT A1 – Form of 0.100% Notes
due 2024

 

UNLESS THIS SECURITY IS PRESENTED
BY AN AUTHORIZED REPRESENTATIVE OF EUROCLEAR BANK SA/NV (“EUROCLEAR”), AND CLEARSTREAM BANKING S.A. (“CLEARSTREAM,
LUXEMBOURG” AND, TOGETHER WITH EUROCLEAR, “EUROCLEAR/CLEARSTREAM”), TO ABBOTT IRELAND FINANCING DAC (THE “COMPANY”)
OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY SECURITY ISSUED IS REGISTERED IN THE NAME OF USB NOMINEES
(UK) LIMITED, OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF ELAVON FINANCIAL SERVICES DAC, AS COMMON
DEPOSITARY (THE “COMMON DEPOSITARY”) FOR EUROCLEAR/CLEARSTREAM (AND ANY PAYMENT IS MADE TO USB NOMINEES (UK) LIMITED
OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE COMMON DEPOSITARY), ANY TRANSFER, PLEDGE OR OTHER
USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF, USB NOMINEES (UK) LIMITED,
HAS AN INTEREST HEREIN.

 

THIS SECURITY IS A GLOBAL SECURITY
AND IS REGISTERED IN THE NAME OF USB NOMINEES (UK) LIMITED, AS NOMINEE OF THE COMMON DEPOSITARY. UNLESS AND UNTIL THIS SECURITY
IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE, CERTIFICATED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS
A WHOLE BY THE COMMON DEPOSITARY TO A NOMINEE THEREOF OR BY A NOMINEE THEREOF TO THE COMMON DEPOSITARY OR ANOTHER NOMINEE OF THE
COMMON DEPOSITARY OR BY THE COMMON DEPOSITARY OR A NOMINEE OF THE COMMON DEPOSITARY TO A SUCCESSOR COMMON DEPOSITARY OR A NOMINEE
OF SUCH SUCCESSOR COMMON DEPOSITARY.

 

    A-1-1 

     

    

 

THIS SECURITY HAS NOT BEEN REGISTERED
UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), OR THE SECURITIES LAWS OF ANY STATE OR OTHER JURISDICTION.
NEITHER THIS SECURITY NOR ANY INTEREST OR PARTICIPATION HEREIN MAY BE REOFFERED, SOLD, ASSIGNED, TRANSFERRED, PLEDGED, ENCUMBERED
OR OTHERWISE DISPOSED OF IN THE ABSENCE OF SUCH REGISTRATION OR UNLESS SUCH TRANSACTION IS EXEMPT FROM, OR NOT SUBJECT TO, SUCH
REGISTRATION. THE HOLDER OF THIS SECURITY, BY ITS ACCEPTANCE HEREOF, AGREES ON ITS OWN BEHALF AND ON BEHALF OF ANY INVESTOR ACCOUNT
FOR WHICH IT HAS PURCHASED SECURITIES, TO OFFER, SELL OR OTHERWISE TRANSFER SUCH SECURITY, PRIOR TO THE DATE (THE “RESALE
RESTRICTION TERMINATION DATE”) 40 DAYS AFTER THE LATER OF THE ORIGINAL ISSUE DATE HEREOF AND THE DATE ON WHICH THIS
SECURITY (OR ANY PREDECESSOR OF SUCH SECURITY) WAS FIRST OFFERED TO PERSONS OTHER THAN DISTRIBUTORS (AS DEFINED IN RULE 902 OF
REGULATION S) IN RELIANCE ON REGULATION S, ONLY (A) TO THE COMPANY OR ANY SUBSIDIARY THEREOF, (B) PURSUANT TO A REGISTRATION STATEMENT
THAT HAS BEEN DECLARED EFFECTIVE UNDER THE SECURITIES ACT, (C) PURSUANT TO OFFERS AND SALES TO NON-US PERSONS (AS DEFINED IN REGULATION
S UNDER THE SECURITIES ACT) THAT OCCUR OUTSIDE THE UNITED STATES WITHIN THE MEANING OF REGULATION S UNDER THE SECURITIES ACT OR
(D) PURSUANT TO ANOTHER AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT, SUBJECT TO THE ISSUER’S
AND THE TRUSTEE’S, REGISTRAR’S OR PAYING AGENT’S RIGHT PRIOR TO ANY SUCH OFFER, SALE OR TRANSFER PURSUANT TO
CLAUSES (C) OR (D) TO REQUIRE THE DELIVERY OF AN OPINION OF COUNSEL, CERTIFICATION AND/OR OTHER INFORMATION SATISFACTORY TO EACH
OF THEM. THIS LEGEND WILL BE REMOVED UPON THE REQUEST OF THE HOLDER AFTER THE RESALE RESTRICTION TERMINATION DATE.

 

BY ITS ACQUISITION HEREOF, THE HOLDER
HEREOF REPRESENTS THAT IT IS NOT A U.S. PERSON NOR IS IT PURCHASING THIS SECURITY FOR THE ACCOUNT OR BENEFIT OF A U.S. PERSON,
OTHER THAN A DISTRIBUTOR, AND IS ACQUIRING THIS SECURITY IN AN OFFSHORE TRANSACTION IN ACCORDANCE WITH REGULATION S UNDER THE SECURITIES
ACT.

 

    A-1-2 

     

    

 

ABBOTT IRELAND FINANCING DAC

0.100% Notes due 2024

 

	No.
    001	€590,000,000
	 	 
	ISIN:
    XS2076154801	 
	 	 
	COMMON
    CODE: 207615480	 
	 	 
	SWISS
    SECURITY NUMBER: 51090712	 

 

This Security is a
Book-Entry Security within the meaning of the Indenture hereinafter referred to and is registered in the name of USB Nominees (UK)
Limited, as nominee of Elavon Financial Services DAC, as common depositary (the “Common Depositary”) for Euroclear
Bank SA/NV (“Euroclear”) and Clearstream Banking S.A. (“Clearstream, Luxembourg”). Unless
and until this Security is exchanged in whole or in part for Securities in definitive, certificated form, this Security may not
be transferred except as a whole by the Common Depositary to a nominee thereof or by a nominee thereof to the Common Depositary
or another nominee of the Common Depositary or by the Common Depositary or a nominee of the Common Depositary to a successor Common
Depositary or a nominee of such successor Common Depositary. This global Security is exchangeable for Securities registered in
the name of a Person other than the nominee of the Common Depositary only in the limited circumstances described in the Indenture,
and no transfer of this Security (other than a transfer of this Security as a whole as described above) may be registered except
in such limited circumstances.

 

    A-1-3 

     

    

 

ABBOTT IRELAND FINANCING
DAC, a designated activity company incorporated under the laws of Ireland (herein called the “Company,” which
term includes any successor Person under the Indenture hereinafter referred to), for value received, hereby promises to pay to
USB Nominees (UK) Limited, as nominee of Elavon Financial Services DAC, as common depositary (the “Common Depositary”)
for Euroclear Bank SA/NV (“Euroclear”) and Clearstream Banking S.A. (“Clearstream, Luxembourg”),
or registered assigns, the principal sum of FIVE HUNDRED NINETY MILLION Euro (€590,000,000), or such other principal sum as
may be indicated on the Schedule of Exchanges attached hereto, on November 19, 2024 and to pay interest thereon from November 19,
2019 or from the most recent Interest Payment Date to which interest has been paid or duly provided for, annually in arrear on
November 19 in each year, commencing November 19, 2020, at the rate of 0.100% per annum, until the principal hereof is paid or
made available for payment.

 

Interest on Securities
of this series shall be computed on the basis of the actual number of days in the period for which interest is being calculated,
and including the last date on which interest was paid or duly provided for on Securities of this series (or from November 19,
2019, if no interest has been paid on Securities of this series), but excluding the next following Interest Payment Date. This
payment convention is referred to as ACTUAL/ACTUAL (ICMA) (as defined in the rulebook of the International Capital Market Association).

 

The interest so payable,
and punctually paid or duly provided for, on any Interest Payment Date will, as provided in such Indenture, be paid to the Holder
in whose name this Security (or one or more Predecessor Securities) is registered in the Security Register (which shall be held
outside the United Kingdom) at the close of the business day (which, for these purposes, is a day on which Euroclear and Clearstream,
Luxembourg settle payments in euro) immediately prior to the relevant Interest Payment Date.

 

Subject to Section
2.5 of the Supplemental Indenture hereinafter referred to, all payments of principal of, and premium, if any, Additional Amounts,
if any, and interest on, Securities of this series, including payments made upon redemption of this Security, shall be payable
in euro. Reference is hereby made to the further provisions of this Security set forth on the reverse hereof, which further provisions
shall for all purposes have the same effect as if set forth at this place.

 

Unless the certificate
of authentication hereon has been executed by the Trustee referred to herein by manual signature, this Security shall not be entitled
to any benefit under the Indenture or be valid or obligatory for any purpose.

 

[signature page follows]

 

    A-1-4 

     

    

 

IN WITNESS WHEREOF,
the Company has caused this instrument to be duly executed.

 

Dated: November 19, 2019

 

	 	ABBOTT IRELAND FINANCING DAC
	 	 
	 	 	 
	 	By:	 
	 	 	Name:
	 	 	Title:

 

    A-1-5 

     

    

 

TRUSTEE’S CERTIFICATE OF AUTHENTICATION

 

This is one of the
Securities of the series designated therein referred to in the within-mentioned Indenture.

 

Dated: November 19, 2019

 

	 	U.S. BANK NATIONAL ASSOCIATION, as Trustee
	 	 
	 	 	 
	 	By:	 
	 	 	Authorized Signatory

 

    A-1-6 

     

    

 

[FORM OF REVERSE OF SECURITY]

 

This Security is one
of a duly authorized issue of securities of the Company (herein called the “Securities”), issued and to be issued
in one or more series under an Indenture, dated as of September 27, 2018 (the “Base Indenture”), among the Company,
Abbott Laboratories (the “Parent Guarantor,” which term includes any successor Person under the Indenture hereinafter
referred to) and U.S. Bank National Association, as Trustee (herein called the “Trustee,” which term includes
any successor trustee under the Indenture), and Supplemental Indenture No. 2, dated as of November 19, 2019 (herein called the
 “Supplemental Indenture”; the Base Indenture, as supplemented or amended from time to time, including by the
Supplemental Indenture, the “Indenture”), among the Company, the Parent Guarantor, the Trustee, Elavon Financial
Services DAC, as paying agent, transfer agent and registrar (the “Paying Agent”, the “Transfer Agent”
and the “Security Registrar”, respectively). Reference is hereby made to the Indenture for a statement of the
respective rights, limitations of rights, duties and immunities thereunder of the Company, the Parent Guarantor, the Trustee and
the Holders of the Securities of this series and of the terms upon which this Security is, and will be, authenticated and delivered.
To the extent any provision of this Security conflicts with the express provisions of the Indenture, the provisions of the Indenture
shall govern and be controlling. This Security is one of the series designated on the face hereof, in an initial aggregate principal
amount of €590,000,000.

 

The Securities of this
series may be redeemed in accordance with the terms of Article IV of the Supplemental Indenture and Article XI of the Base Indenture.

 

The Company or, as
the case may be, the Parent Guarantor, will pay Additional Amounts in accordance with the terms of Article V of the Supplemental
Indenture.

 

The Securities of this
series do not have the benefit of any sinking fund.

 

If an Event of Default
(other than an Event of Default specified in Sections 5.1(5) to 5.1(9) of the Indenture) with respect to Securities of this series
occurs and is continuing, the principal amount of the Securities of this series may be declared due and payable in the manner and
with the effect provided in the Indenture. If an Event of Default specified in Sections 5.1(5) to 5.1(9) of the Indenture with
respect to Securities of this series occurs, the principal amount of the Securities of this series and any accrued interest and
any Additional Amounts of all the Securities of this series shall automatically, and without any declaration or other action on
the part of the Trustee or any Holder, become immediately due and payable.

 

Sections 13.2 and 13.3
of the Indenture apply to the Securities of this series.

 

No reference herein
to the Indenture and no provision of this Security or of the Indenture shall alter or impair the obligation of the Company, which
is absolute and unconditional, to pay the principal of and any premium and interest on this Security at the times, place and rate,
and in the coin or currency, herein prescribed.

 

The transfer and exchange
of Securities of this series may be registered and the Securities of this series may be exchanged as provided in the Indenture.

 

    A-1-7 

     

    

 

The Securities of this
series shall be issued in fully registered form only in denominations of €100,000 and any integral multiple of €1,000
in excess thereof.

 

No service charge shall
be made for any registration of transfer or exchange of the Securities of this series, but the Company or the Security Registrar
may require payment of a sum sufficient to cover any transfer tax, assessments, or similar governmental charge payable in connection
therewith (other than any such transfer taxes, assessments or similar governmental charge payable upon exchange or transfer pursuant
to Sections 9.5 or 11.7 of the Indenture).

 

All terms used in this
Security which are defined in the Indenture shall have the meanings assigned to them in the Indenture.

 

THIS SECURITY SHALL
BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK.

 

*      *      *

 

    A-1-8 

     

    

 

CERTIFICATE TO BE DELIVERED UPON EXCHANGE

OR REGISTRATION OF TRANSFER OF SECURITIES

 

This Certificate
relates to € ___________principal
amount of Securities held in (check applicable space) ____book-entry or ____definitive form by
 ______________________(the “Transferor”).

 

The Transferor (check
one box below):

 

  ̈       has
requested the Security Registrar by written order to deliver in exchange for its beneficial interest in the global Security held
by the Common Depository a Security or Securities in definitive, registered form of authorized denominations in an aggregate principal
amount equal to its beneficial interest in such global Security (or the portion thereof indicated above); or

 

  ̈       has
requested the Security Registrar by written order to exchange or register the transfer of a Security or Securities.

 

	 	 
	 	[INSERT NAME OF TRANSFEROR]
	 	 
	 	 
	Dated:	 
	            By:	 	 

 

    A-1-9 

     

    

 

SCHEDULE OF EXCHANGES

 

The following exchanges,
redemptions or purchases of a part of this Book-Entry Security have been made:

 

	Date of Exchange/
 Redemption/
 Purchase	 	Amount of
 decrease in
 Principal Amount
 of this Book-Entry
 Security	 	Amount of
 increase in
 Principal Amount
 of this Book-Entry
 Security	 	Principal Amount
 of this Book-Entry
 Security following
 such decrease (or
 increase)	 	Signature of
 authorized
 signatory of
 Trustee or Security
 Registrar
	 	 	 	 	 	 	 	 	 
	 	 	 	 	 	 	 	 	 
	 	 	 	 	 	 	 	 	 

 

    A-1-10 

     

    

 

ASSIGNMENT FORM

 

To assign this Security, fill in the form below:

 

I or we assign and transfer this Security to

 

	 
	(Print
    or type assignee’s name, address and zip code)
	 
	 
	(Insert
    assignee’s soc. sec. or tax I.D. No.)

 

and irrevocably appoint _______________________as agent to transfer this Security on the books of the Company. The agent may substitute another to act for him.

 

	Date:	 	     

 

	Your Signature:	 
	 	 	 
	By:	 	 
	Name:	 	    
	Title:	 	 

 

Sign exactly as your name appears on the
other side of this Security.

 

    A-1-11 

     

    

 

 

GUARANTEE

 

FOR VALUE RECEIVED,
the undersigned hereby, jointly and severally with any other Guarantors, unconditionally and irrevocably guarantees (this “Guarantee”)
to the Holder of the accompanying 0.100% Notes due 2024 (the “Note”) issued by Abbott Ireland Financing DAC
(the “Company”) under an Indenture, dated as of September 27, 2018 (together with the Second Supplemental Indenture
thereto, dated as of November 19, 2019, the “Indenture”) among the Company, Abbott Laboratories, as parent guarantor,
U.S. Bank National Association, as trustee thereunder (the “Trustee”), Elavon Financial Services DAC, as paying
agent and transfer agent, and Elavon Financial Services DAC, as register, (a) the full and prompt payment of the principal of and
premium or Redemption Price, if any, on such Note when and as the same shall become due and payable, whether at Stated Maturity,
by acceleration, by redemption or otherwise, and (b) the full and prompt payment of the interest or any Additional Amounts on such
Note when and as the same shall become due and payable, in each case according to the terms of such Note and of the Indenture.
In case of the failure of the Company punctually to pay any such principal, premium or interest, the undersigned hereby agrees
to cause any such payment to be made punctually when and as the same shall become due and payable according to the terms of such
Note and of the Indenture, whether at Stated Maturity, upon acceleration, by redemption or otherwise, and as if such payment were
made by the Company. The undersigned hereby agrees, jointly and severally with any other Guarantors, that its obligations hereunder
shall be as principal and not merely as surety, and shall be absolute and unconditional, and shall not be affected, modified or
impaired by the following: (a) the failure to give notice to the Guarantors of the occurrence of an Event of Default under the
Indenture; (b) the waiver, surrender, compromise, settlement, release or termination of the payment, performance or observance
by the Company or the Guarantors of any or all of the obligations, covenants or agreements of either of them contained in the Indenture
or the Note; (c) the acceleration, extension or any other changes in the time for payment of any principal of or interest or any
premium on any Note or for any other payment under the Indenture or of the time for performance of any other obligations, covenants
or agreements under or arising out of the Indenture or the Note; (d) the modification or amendment (whether material or otherwise)
of any obligation, covenant or agreement set forth in the Indenture or the Note; (e) the taking or the omission of any of the actions
referred to in the Indenture and in any of the actions under the Note; (f) any failure, omission, delay or lack on the part of
the Trustee to enforce, assert or exercise any right, power or remedy conferred on the Trustee in the Indenture, or any other action
or acts on the part of the Trustee or any of the Holders from time to time of the Note; (g) the voluntary or involuntary liquidation,
dissolution, sale or other disposition of all or substantially all the assets, marshaling of assets and liabilities, receivership,
insolvency, bankruptcy, assignment for the benefit of creditors, reorganization, arrangement, composition with creditors or readjustment
of, or other similar proceedings affecting the Guarantors or the Company or any of the assets of any of them, or any allegation
or contest of the validity of this Guarantee in any such proceeding; (h) to the extent permitted by law, the release or discharge
by operation of law of the Guarantors from the performance or observance of any obligation, covenant or agreement contained in
the Indenture; (i) to the extent permitted by law, the release or discharge by operation of law of the Company from the performance
or observance of any obligation, covenant or agreement contained in the Indenture; (j) the default or failure of the Company or
the Trustee fully to perform any of its obligations set forth in the Indenture or the Note; (k) the invalidity, irregularity or
unenforceability of the Indenture or the Note or any part of any thereof; (l) any judicial or governmental action affecting the
Company or any Note or consent or indulgence granted to the Company by the Holders or by the Trustee; or (m) the recovery of any
judgment against the Company or any action to enforce the same or any other circumstance which might constitute a legal or equitable
discharge of a surety or guarantor. The undersigned hereby waives diligence, presentment, demand of payment, filing of claims with
a court in the event of merger, sale, lease or conveyance of all or substantially all of its assets, insolvency or bankruptcy of
the Company, any right to require a proceeding first against the Company, protest or notice with respect to such Note or the indebtedness
evidenced thereby and all demands whatsoever, and covenants that this Guarantee shall not be discharged except by complete performance
of the obligations contained in such Note and in this Guarantee.

 

    A-1-12 

     

    

 

No reference herein
to such Indenture and no provision of this Guarantee or of such Indenture shall alter or impair the guarantee of the undersigned,
which is absolute and unconditional, of the full and prompt payment of the principal of and premium, if any, and interest on the
Note.

 

THIS GUARANTEE SHALL
BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK.

 

This Guarantee shall
not be valid or obligatory for any purpose until the certificate of authentication on the Note shall have been executed by the
Trustee under the Indenture referred to above by the manual signature of one of its authorized officers. The validity and enforceability
of this Guarantee shall not be affected by the fact that it is not affixed to any particular Note.

 

An Event of Default
under the Indenture or the Note shall constitute an event of default under this Guarantee, and shall entitle the Holders of Notes
to accelerate the obligations of the undersigned hereunder in the same manner and to the same extent as the obligations of the
Company under the Indenture and the Note.

 

Notwithstanding any
other provision of this Guarantee to the contrary, the undersigned hereby waives any claims or other rights which it may now have
or hereafter acquire against the Company that arise from the existence or performance of its obligations under this Guarantee (all
such claims and rights are referred to as “Guarantor’s Conditional Rights”), including, without limitation,
any right of subrogation, reimbursement, exoneration, contribution, or indemnification, any right to participate in any claim or
remedy against the Company, whether or not such claim, remedy or right arises in equity or under contract, statute or common law,
by any payment made hereunder or otherwise, including without limitation, the right to take or receive from the Company, directly
or indirectly, in cash or other property or by setoff or in any other manner, payment or security on account of such claim or other
rights. Each of the Guarantors hereby agrees not to exercise any rights which may be acquired by way of contribution under this
Guarantee or any other agreement, by any payment made hereunder or otherwise, including, without limitation, the right to take
or receive from any other Guarantor, directly or indirectly, in cash or other property or by setoff or in any other manner, payment
or security on account of such contribution rights. If, notwithstanding the foregoing provisions, any amount shall be paid to the
undersigned on account of the Guarantor’s Conditional Rights and either (i) such amount is paid to such undersigned party
at any time when the Note shall not have been paid or performed in full, or (ii) regardless of when such amount is paid to such
undersigned party, any payment made by the Company to any Holder is determined to be a Preferential Payment, then such amount paid
to the undersigned shall be held in trust for the benefit of such Holder and shall forthwith be paid to such Holder to be credited
and applied upon the Note, whether matured or unmatured. Any such payment is herein referred to as a “Preferential Payment”
to the extent the Company makes any payment to any Holder in connection with the Note, and any or all of such payment is subsequently
invalidated, declared to be fraudulent or preferential, set aside or required to be repaid or paid over to a trustee, receiver
or any other entity, whether under any bankruptcy act or otherwise.

 

    A-1-13 

     

    

 

To the extent that
any of the provisions of the immediately preceding paragraph shall not be enforceable, the undersigned agrees that until such time
as the Note has been paid and performed in full and the period of time has expired during which any payment made by the Company
or the undersigned to a Holder may be determined to be a Preferential Payment, Guarantor’s Conditional Rights to the extent
not validly waived shall be subordinate to Holders’ right to full payment and performance of the Note and the undersigned
shall not enforce any of Guarantor’s Conditional Rights until such time as the Note has been paid and performed in full and
the period of time has expired during which any payment made by the Company or the undersigned to Holders may be determined to
be a Preferential Payment.

 

The obligations of
the undersigned to the Holders of the Note and to the Trustee pursuant to this Guarantee and the Indenture are expressly set forth
in Article Fourteen of the Indenture and reference is hereby made to the Indenture for the precise terms of this Guarantee and
all of the other provisions of the Indenture to which this Guarantee relates.

 

Capitalized terms used
in this Guarantee which are not defined herein shall have the meanings assigned to them in the Indenture.

 

[Remainder of page intentionally left
blank]

 

    A-1-14 

     

    

 

IN WITNESS WHEREOF, the undersigned has caused this Guarantee
to be duly executed.

 

Dated: November 19, 2019

 

	 	ABBOTT LABORATORIES
	 	 	 
	 	 	 
	 	By:	 
	 	 	Name:
	 	 	Title:

 

    A-1-15 

     

    

 

EXHIBIT A2 – Form of 0.375% Notes
due 2027

 

UNLESS THIS SECURITY IS PRESENTED
BY AN AUTHORIZED REPRESENTATIVE OF EUROCLEAR BANK SA/NV (“EUROCLEAR”), AND CLEARSTREAM BANKING S.A. (“CLEARSTREAM,
LUXEMBOURG” AND, TOGETHER WITH EUROCLEAR, “EUROCLEAR/CLEARSTREAM”), TO ABBOTT IRELAND FINANCING DAC (THE “COMPANY”)
OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY SECURITY ISSUED IS REGISTERED IN THE NAME OF USB NOMINEES
(UK) LIMITED, OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF ELAVON FINANCIAL SERVICES DAC, AS COMMON
DEPOSITARY (THE “COMMON DEPOSITARY”) FOR EUROCLEAR/CLEARSTREAM (AND ANY PAYMENT IS MADE TO USB NOMINEES (UK) LIMITED
OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE COMMON DEPOSITARY), ANY TRANSFER, PLEDGE OR OTHER
USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF, USB NOMINEES (UK) LIMITED,
HAS AN INTEREST HEREIN.

 

THIS SECURITY IS A GLOBAL SECURITY
AND IS REGISTERED IN THE NAME OF USB NOMINEES (UK) LIMITED, AS NOMINEE OF THE COMMON DEPOSITARY. UNLESS AND UNTIL THIS SECURITY
IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE, CERTIFICATED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS
A WHOLE BY THE COMMON DEPOSITARY TO A NOMINEE THEREOF OR BY A NOMINEE THEREOF TO THE COMMON DEPOSITARY OR ANOTHER NOMINEE OF THE
COMMON DEPOSITARY OR BY THE COMMON DEPOSITARY OR A NOMINEE OF THE COMMON DEPOSITARY TO A SUCCESSOR COMMON DEPOSITARY OR A NOMINEE
OF SUCH SUCCESSOR COMMON DEPOSITARY.

 

    A-2-1

     

    

 

THIS SECURITY HAS NOT BEEN REGISTERED
UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), OR THE SECURITIES LAWS OF ANY STATE OR OTHER JURISDICTION.
NEITHER THIS SECURITY NOR ANY INTEREST OR PARTICIPATION HEREIN MAY BE REOFFERED, SOLD, ASSIGNED, TRANSFERRED, PLEDGED, ENCUMBERED
OR OTHERWISE DISPOSED OF IN THE ABSENCE OF SUCH REGISTRATION OR UNLESS SUCH TRANSACTION IS EXEMPT FROM, OR NOT SUBJECT TO, SUCH
REGISTRATION. THE HOLDER OF THIS SECURITY, BY ITS ACCEPTANCE HEREOF, AGREES ON ITS OWN BEHALF AND ON BEHALF OF ANY INVESTOR ACCOUNT
FOR WHICH IT HAS PURCHASED SECURITIES, TO OFFER, SELL OR OTHERWISE TRANSFER SUCH SECURITY, PRIOR TO THE DATE (THE “RESALE
RESTRICTION TERMINATION DATE”) 40 DAYS AFTER THE LATER OF THE ORIGINAL ISSUE DATE HEREOF AND THE DATE ON WHICH THIS
SECURITY (OR ANY PREDECESSOR OF SUCH SECURITY) WAS FIRST OFFERED TO PERSONS OTHER THAN DISTRIBUTORS (AS DEFINED IN RULE 902 OF
REGULATION S) IN RELIANCE ON REGULATION S, ONLY (A) TO THE COMPANY OR ANY SUBSIDIARY THEREOF, (B) PURSUANT TO A REGISTRATION STATEMENT
THAT HAS BEEN DECLARED EFFECTIVE UNDER THE SECURITIES ACT, (C) PURSUANT TO OFFERS AND SALES TO NON-US PERSONS (AS DEFINED IN REGULATION
S UNDER THE SECURITIES ACT) THAT OCCUR OUTSIDE THE UNITED STATES WITHIN THE MEANING OF REGULATION S UNDER THE SECURITIES ACT OR
(D) PURSUANT TO ANOTHER AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT, SUBJECT TO THE ISSUER’S
AND THE TRUSTEE’S, REGISTRAR’S OR PAYING AGENT’S RIGHT PRIOR TO ANY SUCH OFFER, SALE OR TRANSFER PURSUANT TO
CLAUSES (C) OR (D) TO REQUIRE THE DELIVERY OF AN OPINION OF COUNSEL, CERTIFICATION AND/OR OTHER INFORMATION SATISFACTORY TO EACH
OF THEM. THIS LEGEND WILL BE REMOVED UPON THE REQUEST OF THE HOLDER AFTER THE RESALE RESTRICTION TERMINATION DATE.

 

BY ITS ACQUISITION HEREOF, THE HOLDER
HEREOF REPRESENTS THAT IT IS NOT A U.S. PERSON NOR IS IT PURCHASING THIS SECURITY FOR THE ACCOUNT OR BENEFIT OF A U.S. PERSON,
OTHER THAN A DISTRIBUTOR, AND IS ACQUIRING THIS SECURITY IN AN OFFSHORE TRANSACTION IN ACCORDANCE WITH REGULATION S UNDER THE SECURITIES
ACT.

 

    A-2-2

     

    

 

ABBOTT IRELAND FINANCING DAC

0.375% Notes due 2027

 

	No. 001	€590,000,000
	 	 
	ISIN: XS2076155105	 
	 	 
	COMMON CODE: 207615510	 
	 	 
	SWISS SECURITY NUMBER:
    51090713	 

 

This Security is a
Book-Entry Security within the meaning of the Indenture hereinafter referred to and is registered in the name of USB Nominees (UK)
Limited, as nominee of Elavon Financial Services DAC, as common depositary (the “Common Depositary”) for Euroclear
Bank SA/NV (“Euroclear”) and Clearstream Banking S.A. (“Clearstream, Luxembourg”). Unless
and until this Security is exchanged in whole or in part for Securities in definitive, certificated form, this Security may not
be transferred except as a whole by the Common Depositary to a nominee thereof or by a nominee thereof to the Common Depositary
or another nominee of the Common Depositary or by the Common Depositary or a nominee of the Common Depositary to a successor Common
Depositary or a nominee of such successor Common Depositary. This global Security is exchangeable for Securities registered in
the name of a Person other than the nominee of the Common Depositary only in the limited circumstances described in the Indenture,
and no transfer of this Security (other than a transfer of this Security as a whole as described above) may be registered except
in such limited circumstances.

 

    A-2-3

     

    

 

ABBOTT IRELAND FINANCING
DAC, a designated activity company incorporated under the laws of Ireland (herein called the “Company,” which
term includes any successor Person under the Indenture hereinafter referred to), for value received, hereby promises to pay to
USB Nominees (UK) Limited, as nominee of Elavon Financial Services DAC, as common depositary (the “Common Depositary”)
for Euroclear Bank SA/NV (“Euroclear”) and Clearstream Banking S.A. (“Clearstream, Luxembourg”),
or registered assigns, the principal sum of FIVE HUNDRED NINETY MILLION Euro (€590,000,000), or such other principal sum as
may be indicated on the Schedule of Exchanges attached hereto, on November 19, 2027 and to pay interest thereon from November 19,
2019 or from the most recent Interest Payment Date to which interest has been paid or duly provided for, annually in arrear on
November 19 in each year, commencing November 19, 2020, at the rate of 0.375% per annum, until the principal hereof is paid or
made available for payment.

 

Interest on Securities
of this series shall be computed on the basis of the actual number of days in the period for which interest is being calculated,
and including the last date on which interest was paid or duly provided for on Securities of this series (or from November 19,
2019, if no interest has been paid on Securities of this series), but excluding the next following Interest Payment Date. This
payment convention is referred to as ACTUAL/ACTUAL (ICMA) (as defined in the rulebook of the International Capital Market Association).

 

The interest so payable,
and punctually paid or duly provided for, on any Interest Payment Date will, as provided in such Indenture, be paid to the Holder
in whose name this Security (or one or more Predecessor Securities) is registered in the Security Register (which shall be held
outside the United Kingdom) at the close of the business day (which, for these purposes, is a day on which Euroclear and Clearstream,
Luxembourg settle payments in euro) immediately prior to the relevant Interest Payment Date.

 

Subject to Section
2.5 of the Supplemental Indenture hereinafter referred to, all payments of principal of, and premium, if any, Additional Amounts,
if any, and interest on, Securities of this series, including payments made upon redemption of this Security, shall be payable
in euro.

 

Reference is hereby
made to the further provisions of this Security set forth on the reverse hereof, which further provisions shall for all purposes
have the same effect as if set forth at this place.

 

Unless the certificate
of authentication hereon has been executed by the Trustee referred to herein by manual signature, this Security shall not be entitled
to any benefit under the Indenture or be valid or obligatory for any purpose.

 

[signature page follows]

 

    A-2-4

     

    

 

IN WITNESS WHEREOF,
the Company has caused this instrument to be duly executed.

 

Dated: November 19, 2019

 

	 	ABBOTT IRELAND FINANCING DAC
	 	 
	 	 	 
	 	By:	 
	 	 	Name:
	 	 	Title:

 

    A-2-5

     

    

 

TRUSTEE’S CERTIFICATE OF AUTHENTICATION

 

This is one of the
Securities of the series designated therein referred to in the within-mentioned Indenture.

 

Dated: November 19, 2019

 

	 	U.S. BANK NATIONAL ASSOCIATION, as Trustee
	 	 
	 	 	 
	 	By:	 
	 	 	Authorized Signatory

 

    A-2-6

     

    

 

 

[FORM OF REVERSE OF SECURITY]

 

This Security is one
of a duly authorized issue of securities of the Company (herein called the “Securities”), issued and to be issued
in one or more series under an Indenture, dated as of September 27, 2018 (the “Base Indenture”), among the Company,
Abbott Laboratories (the “Parent Guarantor,” which term includes any successor Person under the Indenture hereinafter
referred to) and U.S. Bank National Association, as Trustee (herein called the “Trustee,” which term includes
any successor trustee under the Indenture), and Supplemental Indenture No. 2, dated as of November 19, 2019 (herein called the
 “Supplemental Indenture”; the Base Indenture, as supplemented or amended from time to time, including by the
Supplemental Indenture, the “Indenture”), among the Company, the Parent Guarantor, the Trustee, Elavon Financial
Services DAC, as paying agent, transfer agent and registrar (the “Paying Agent”, the “Transfer Agent”
and the “Security Registrar”, respectively). Reference is hereby made to the Indenture for a statement of the
respective rights, limitations of rights, duties and immunities thereunder of the Company, the Parent Guarantor, the Trustee and
the Holders of the Securities of this series and of the terms upon which this Security is, and will be, authenticated and delivered.
To the extent any provision of this Security conflicts with the express provisions of the Indenture, the provisions of the Indenture
shall govern and be controlling. This Security is one of the series designated on the face hereof, in an initial aggregate principal
amount of €590,000,000.

 

The Securities of this
series may be redeemed in accordance with the terms of Article IV of the Supplemental Indenture and Article XI of the Base Indenture.

 

The Company or, as
the case may be, the Parent Guarantor, will pay Additional Amounts in accordance with the terms of Article V of the Supplemental
Indenture.

 

The Securities of this
series do not have the benefit of any sinking fund.

 

If an Event of Default
(other than an Event of Default specified in Sections 5.1(5) to 5.1(9) of the Indenture) with respect to Securities of this series
occurs and is continuing, the principal amount of the Securities of this series may be declared due and payable in the manner and
with the effect provided in the Indenture. If an Event of Default specified in Sections 5.1(5) to 5.1(9) of the Indenture with
respect to Securities of this series occurs, the principal amount of the Securities of this series and any accrued interest and
any Additional Amounts of all the Securities of this series shall automatically, and without any declaration or other action on
the part of the Trustee or any Holder, become immediately due and payable.

 

Sections 13.2 and 13.3
of the Indenture apply to the Securities of this series.

 

No reference herein
to the Indenture and no provision of this Security or of the Indenture shall alter or impair the obligation of the Company, which
is absolute and unconditional, to pay the principal of and any premium and interest on this Security at the times, place and rate,
and in the coin or currency, herein prescribed.

 

The transfer and exchange
of Securities of this series may be registered and the Securities of this series may be exchanged as provided in the Indenture.

 

    A-2-7

     

    

 

The Securities of this
series shall be issued in fully registered form only in denominations of €100,000 and any integral multiple of €1,000
in excess thereof.

 

No service charge shall
be made for any registration of transfer or exchange of the Securities of this series, but the Company or the Security Registrar
may require payment of a sum sufficient to cover any transfer tax, assessments, or similar governmental charge payable in connection
therewith (other than any such transfer taxes, assessments or similar governmental charge payable upon exchange or transfer pursuant
to Sections 9.5 or 11.7 of the Indenture).

 

All terms used in this
Security which are defined in the Indenture shall have the meanings assigned to them in the Indenture.

 

THIS SECURITY SHALL
BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK.

 

*      *      *

 

    A-2-8

     

    

 

CERTIFICATE TO BE DELIVERED UPON EXCHANGE

OR REGISTRATION OF TRANSFER OF SECURITIES

 

This Certificate
relates to € ___________ principal
amount of Securities held in (check applicable space) ____ book-entry or _____ definitive form by
  _____________________ (the “Transferor”).

 

The Transferor (check
one box below):

 

 ̈       has
requested the Security Registrar by written order to deliver in exchange for its beneficial interest in the global Security held
by the Common Depository a Security or Securities in definitive, registered form of authorized denominations in an aggregate principal
amount equal to its beneficial interest in such global Security (or the portion thereof indicated above); or

 

 ̈        has
requested the Security Registrar by written order to exchange or register the transfer of a Security or Securities.

 

	 	 
	 	[INSERT NAME OF TRANSFEROR]
	 	 
	 	 
	Dated:	 
	            By:	 	 

 

    A-2-9

     

    

 

SCHEDULE OF EXCHANGES

 

The following exchanges,
redemptions or purchases of a part of this Book-Entry Security have been made:

 

	Date of Exchange/
 Redemption/
 Purchase	 	Amount of
 decrease in
 Principal Amount
 of this Book-Entry
 Security	 	Amount of
 increase in
 Principal Amount
 of this Book-Entry
 Security	 	Principal Amount
 of this Book-Entry
 Security following
 such decrease (or
 increase)	 	Signature of
 authorized
 signatory of
 Trustee or Security
 Registrar
	 	 	 	 	 	 	 	 	 
	 	 	 	 	 	 	 	 	 
	 	 	 	 	 	 	 	 	 

 

    A-2-10

     

    

 

ASSIGNMENT FORM

 

To assign this Security, fill in the form below:

 

I or we assign and transfer this Security to

 

	 
	(Print or type assignee’s name, address and zip code)
	 
	 
	(Insert assignee’s soc. sec. or tax I.D. No.)

 

and irrevocably appoint ________________________ as agent to transfer this Security on the books of the Company. The agent may substitute another to act for him.

 

	Date:	 	     

 

	Your Signature:	 
	 	 	 
	By:	 	 
	Name:	 	    
	Title:	 	 

 

Sign exactly as your name appears on the
other side of this Security.

 

    A-2-11

     

    

 

GUARANTEE

 

FOR VALUE RECEIVED,
the undersigned hereby, jointly and severally with any other Guarantors, unconditionally and irrevocably guarantees (this “Guarantee”)
to the Holder of the accompanying 0.375% Notes due 2027 (the “Note”) issued by Abbott Ireland Financing DAC
(the “Company”) under an Indenture, dated as of September 27, 2018 (together with the Second Supplemental Indenture
thereto, dated as of November 19, 2019, the “Indenture”) among the Company, Abbott Laboratories, as parent guarantor,
U.S. Bank National Association, as trustee thereunder (the “Trustee”), Elavon Financial Services DAC, as paying
agent and transfer agent, and Elavon Financial Services DAC, as register, (a) the full and prompt payment of the principal of and
premium or Redemption Price, if any, on such Note when and as the same shall become due and payable, whether at Stated Maturity,
by acceleration, by redemption or otherwise, and (b) the full and prompt payment of the interest or any Additional Amounts on such
Note when and as the same shall become due and payable, in each case according to the terms of such Note and of the Indenture.
In case of the failure of the Company punctually to pay any such principal, premium or interest, the undersigned hereby agrees
to cause any such payment to be made punctually when and as the same shall become due and payable according to the terms of such
Note and of the Indenture, whether at Stated Maturity, upon acceleration, by redemption or otherwise, and as if such payment were
made by the Company. The undersigned hereby agrees, jointly and severally with any other Guarantors, that its obligations hereunder
shall be as principal and not merely as surety, and shall be absolute and unconditional, and shall not be affected, modified or
impaired by the following: (a) the failure to give notice to the Guarantors of the occurrence of an Event of Default under the
Indenture; (b) the waiver, surrender, compromise, settlement, release or termination of the payment, performance or observance
by the Company or the Guarantors of any or all of the obligations, covenants or agreements of either of them contained in the Indenture
or the Note; (c) the acceleration, extension or any other changes in the time for payment of any principal of or interest or any
premium on any Note or for any other payment under the Indenture or of the time for performance of any other obligations, covenants
or agreements under or arising out of the Indenture or the Note; (d) the modification or amendment (whether material or otherwise)
of any obligation, covenant or agreement set forth in the Indenture or the Note; (e) the taking or the omission of any of the actions
referred to in the Indenture and in any of the actions under the Note; (f) any failure, omission, delay or lack on the part of
the Trustee to enforce, assert or exercise any right, power or remedy conferred on the Trustee in the Indenture, or any other action
or acts on the part of the Trustee or any of the Holders from time to time of the Note; (g) the voluntary or involuntary liquidation,
dissolution, sale or other disposition of all or substantially all the assets, marshaling of assets and liabilities, receivership,
insolvency, bankruptcy, assignment for the benefit of creditors, reorganization, arrangement, composition with creditors or readjustment
of, or other similar proceedings affecting the Guarantors or the Company or any of the assets of any of them, or any allegation
or contest of the validity of this Guarantee in any such proceeding; (h) to the extent permitted by law, the release or discharge
by operation of law of the Guarantors from the performance or observance of any obligation, covenant or agreement contained in
the Indenture; (i) to the extent permitted by law, the release or discharge by operation of law of the Company from the performance
or observance of any obligation, covenant or agreement contained in the Indenture; (j) the default or failure of the Company or
the Trustee fully to perform any of its obligations set forth in the Indenture or the Note; (k) the invalidity, irregularity or
unenforceability of the Indenture or the Note or any part of any thereof; (l) any judicial or governmental action affecting the
Company or any Note or consent or indulgence granted to the Company by the Holders or by the Trustee; or (m) the recovery of any
judgment against the Company or any action to enforce the same or any other circumstance which might constitute a legal or equitable
discharge of a surety or guarantor. The undersigned hereby waives diligence, presentment, demand of payment, filing of claims with
a court in the event of merger, sale, lease or conveyance of all or substantially all of its assets, insolvency or bankruptcy of
the Company, any right to require a proceeding first against the Company, protest or notice with respect to such Note or the indebtedness
evidenced thereby and all demands whatsoever, and covenants that this Guarantee shall not be discharged except by complete performance
of the obligations contained in such Note and in this Guarantee.

 

    A-2-12

     

    

 

No reference herein
to such Indenture and no provision of this Guarantee or of such Indenture shall alter or impair the guarantee of the undersigned,
which is absolute and unconditional, of the full and prompt payment of the principal of and premium, if any, and interest on the
Note.

 

THIS GUARANTEE SHALL
BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK.

 

This Guarantee shall
not be valid or obligatory for any purpose until the certificate of authentication on the Note shall have been executed by the
Trustee under the Indenture referred to above by the manual signature of one of its authorized officers. The validity and enforceability
of this Guarantee shall not be affected by the fact that it is not affixed to any particular Note.

 

An Event of Default
under the Indenture or the Note shall constitute an event of default under this Guarantee, and shall entitle the Holders of Notes
to accelerate the obligations of the undersigned hereunder in the same manner and to the same extent as the obligations of the
Company under the Indenture and the Note.

 

Notwithstanding any
other provision of this Guarantee to the contrary, the undersigned hereby waives any claims or other rights which it may now have
or hereafter acquire against the Company that arise from the existence or performance of its obligations under this Guarantee (all
such claims and rights are referred to as “Guarantor’s Conditional Rights”), including, without limitation,
any right of subrogation, reimbursement, exoneration, contribution, or indemnification, any right to participate in any claim or
remedy against the Company, whether or not such claim, remedy or right arises in equity or under contract, statute or common law,
by any payment made hereunder or otherwise, including without limitation, the right to take or receive from the Company, directly
or indirectly, in cash or other property or by setoff or in any other manner, payment or security on account of such claim or other
rights. Each of the Guarantors hereby agrees not to exercise any rights which may be acquired by way of contribution under this
Guarantee or any other agreement, by any payment made hereunder or otherwise, including, without limitation, the right to take
or receive from any other Guarantor, directly or indirectly, in cash or other property or by setoff or in any other manner, payment
or security on account of such contribution rights. If, notwithstanding the foregoing provisions, any amount shall be paid to the
undersigned on account of the Guarantor’s Conditional Rights and either (i) such amount is paid to such undersigned party
at any time when the Note shall not have been paid or performed in full, or (ii) regardless of when such amount is paid to such
undersigned party, any payment made by the Company to any Holder is determined to be a Preferential Payment, then such amount paid
to the undersigned shall be held in trust for the benefit of such Holder and shall forthwith be paid to such Holder to be credited
and applied upon the Note, whether matured or unmatured. Any such payment is herein referred to as a “Preferential Payment”
to the extent the Company makes any payment to any Holder in connection with the Note, and any or all of such payment is subsequently
invalidated, declared to be fraudulent or preferential, set aside or required to be repaid or paid over to a trustee, receiver
or any other entity, whether under any bankruptcy act or otherwise.

 

    A-2-13

     

    

 

To the extent that
any of the provisions of the immediately preceding paragraph shall not be enforceable, the undersigned agrees that until such time
as the Note has been paid and performed in full and the period of time has expired during which any payment made by the Company
or the undersigned to a Holder may be determined to be a Preferential Payment, Guarantor’s Conditional Rights to the extent
not validly waived shall be subordinate to Holders’ right to full payment and performance of the Note and the undersigned
shall not enforce any of Guarantor’s Conditional Rights until such time as the Note has been paid and performed in full and
the period of time has expired during which any payment made by the Company or the undersigned to Holders may be determined to
be a Preferential Payment.

 

The obligations of
the undersigned to the Holders of the Note and to the Trustee pursuant to this Guarantee and the Indenture are expressly set forth
in Article Fourteen of the Indenture and reference is hereby made to the Indenture for the precise terms of this Guarantee and
all of the other provisions of the Indenture to which this Guarantee relates.

 

Capitalized terms used
in this Guarantee which are not defined herein shall have the meanings assigned to them in the Indenture.

 

[Remainder of page intentionally left
blank]

 

    A-2-14

     

    

 

IN WITNESS WHEREOF, the undersigned has caused this Guarantee
to be duly executed.

 

Dated: November 19, 2019

 

	 	ABBOTT LABORATORIES
	 	 
	 	 	 
	 	By:	 
	 	 	Name:
	 	 	Title:

 

    A-2-15

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