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                 OPTIONAL GUARANTEED MINIMUM WITHDRAWAL BENEFIT
                     MAXIMUM ANNIVERSARY VALUE ENDORSEMENT

Notwithstanding any provision in the Contract or Certificate ("Contract") to the
contrary, this Endorsement becomes a part of the Contract to which it is
attached. Should any provision in this Endorsement conflict with the Contract,
the provisions of this Endorsement will prevail.

Subject to the terms and conditions set forth herein, this optional Endorsement
provides a Guaranteed Minimum Withdrawal Benefit ("GMWB") that guarantees an
amount available for Withdrawal not to exceed a maximum annual dollar amount to
be distributed over a specified number of years, even if the Contract Value has
been reduced to zero due to unfavorable investment performance.

EFFECTIVE DATE:  [DATE]

                                   DEFINITIONS

Terms not defined in this Endorsement shall have the same meaning given to them
in the Contract.

ANNIVERSARY VALUE
The Contract Value minus any Ineligible Purchase Payments as measured one year
from the Effective Date and on subsequent Contract anniversaries.

BENEFIT BASE
A component of the calculation of the GMWB, which is used to determine the total
amount of guaranteed Withdrawals, the Minimum Withdrawal Period, the GMWB
Charge, and the Maximum Annual Withdrawal Amount.

BENEFIT BASE EVALUATION PERIOD
The period of time over which Anniversary Values are considered in determining
the Benefit Base.

BENEFIT YEAR
Each consecutive one year period starting on the Effective Date.

EFFECTIVE DATE
The date shown above when this Endorsement becomes effective. If this
Endorsement is elected at Contract issue, the Effective Date is the date Your
Contract is issued.

ELIGIBLE PURCHASE PAYMENTS
The Purchase Payments or portion thereof that are included in the calculation of
the Benefit Base.

EXCESS WITHDRAWAL
The portion of any Withdrawal that makes the total of all Withdrawals in a
Benefit Year exceed the Maximum Annual Withdrawal Amount in that Benefit Year.

INELIGIBLE PURCHASE PAYMENTS
Ineligible Purchase Payments are Purchase Payments that are not included in the
calculation of the Benefit Base.

MAXIMUM ANNUAL WITHDRAWAL AMOUNT ("MAWA")
The maximum amount available to be withdrawn each Benefit Year under the GMWB.

MAXIMUM ANNUAL WITHDRAWAL PERCENTAGE ("MAWP")
The maximum percentage used to determine the maximum amount available to be
withdrawn each Benefit Year under the GMWB.

MINIMUM WITHDRAWAL PERIOD ("MWP")
The minimum period of time over which You may take Withdrawals under the GMWB.

SPOUSAL BENEFICIARY
Your spouse, if designated as Your primary Beneficiary on the date of Your
death, who elects to continue the Contract as the new Owner or Participant
("Owner") upon Your death.

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WITHDRAWAL
The amount of any full or partial surrender of Contract Value and any fees or
charges attributable to the surrendered amount.

   GUARANTEED MINIMUM WITHDRAWAL BENEFIT MAXIMUM ANNIVERSARY VALUE PROVISIONS

This Endorsement provides a GMWB subject to the terms and conditions described
herein.

GMWB CHARGE
The GMWB charge is an annualized charge deducted from Your Contract Value on a
quarterly basis beginning one quarter following the Effective Date and ending on
the termination of the Endorsement.

The amount of the GMWB charge will equal:

<TABLE>
<CAPTION>
BENEFIT YEAR          ANNUAL CHARGE PERCENTAGE             AS A PERCENTAGE OF
------------          ------------------------             ------------------
<S>                   <C>                                  <C>
  Years 0+                      0.65%                          Benefit Base
</TABLE>

BENEFIT BASE EVALUATION PERIOD
A Benefit Base Evaluation Period begins on the Effective Date and extends to the
10th Benefit Year anniversary.

CALCULATION OF THE COMPONENTS OF THE GMWB
The GMWB is available for Withdrawal at any time while the Endorsement is in
effect and prior to any termination of the GMWB. The amount of Withdrawals and
time period over which You can take Withdrawals under the GMWB may change over
time as a result of Withdrawal activity or Benefit Base increase. Withdrawals
made under this Endorsement are treated like any other Withdrawal under the
Contract for purposes of calculating Contract Value, Withdrawal Charges, and any
other benefits under the Contract. Withdrawals in excess of the Penalty Free
Withdrawal amount will be assessed a Withdrawal Charge, if applicable. We
reserve the right to limit the investment options available under Your Contract
if You elect the GMWB.

To determine the GMWB, We calculate each of the following components: Benefit
Base and MAWA. The calculations for each component are detailed below.

BENEFIT BASE
The initial Benefit Base is Eligible Purchase Payments multiplied by the
percentage as specified in the table below.

The table below identifies the Eligible Purchase Payments included in the
calculation of the Benefit Base, as determined by the time elapsed between the
Effective Date and the day on which Purchase Payments are received by Us and
deposited into Your Contract. Payment Enhancements, if applicable, are not
considered Eligible Purchase Payments.

<TABLE>
<CAPTION>
                                                 PERCENTAGE INCLUDED IN
TIME ELAPSED SINCE EFFECTIVE DATE             THE BENEFIT BASE CALCULATION
---------------------------------             ----------------------------
<S>                                           <C>
          0-2 Years                                        100%
</TABLE>

On any Benefit Year anniversary occurring during the Benefit Base Evaluation
Period, the Benefit Base is automatically increased to the Anniversary Value
when the Anniversary Value is greater than (a) and (b), where:

        (a)   is the current Benefit Base; and

        (b)   is all previous Anniversary Values during any Benefit Base
              Evaluation Period.

The Benefit Base is not used in the calculation of Contract Value or any other
benefits under the Contract. We reserve the right to limit the Eligible Purchase
Payments to a maximum of $1,000,000.

MAXIMUM ANNUAL WITHDRAWAL AMOUNT ("MAWA")
The MAWA is an amount calculated as a percentage of the Benefit Base. The
applicable Maximum Annual Withdrawal Percentage ("MAWP") used to calculate the
MAWA is determined by when the first Withdrawal is made by You, as specified in
the table below.

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<TABLE>
<CAPTION>
                                  MAXIMUM ANNUAL           MAXIMUM ANNUAL
                              WITHDRAWAL PERCENTAGE          WITHDRAWAL             MAXIMUM ANNUAL
                              WHEN EXTENSION IS NOT       PERCENTAGE WHEN          WITHDRAWAL AS A
 TIME OF FIRST WITHDRAWAL             ELECTED           EXTENSION IS ELECTED        PERCENTAGE OF:
 ------------------------     ---------------------     --------------------       ---------------
<S>                           <C>                         <C>                      <C>
  Before 5th Benefit Year               5%                       5%                  Benefit Base
        anniversary
  On or after 5th Benefit               7%                       7%                  Benefit Base
     Year anniversary
 On or after 10th Benefit               10%                      7%                  Benefit Base
     Year anniversary
 On or after 20th Benefit               10%                      10%                 Benefit Base
     Year anniversary
</TABLE>

If You are taking required minimum distributions ("RMD") from the Contract, the
MAWA is the greater of the MAWA as described above or the annual RMD amount
applicable to the Contract Value only.

The MAWA can be withdrawn throughout each Benefit Year. If You do not withdraw
the entire MAWA in a Benefit Year, You will maintain Your Minimum Withdrawal
Period, but the MAWA will not increase. Excess Withdrawals in any Benefit Year
may reduce Your future MAWA. See IMPACT OF WITHDRAWALS section below.

If the Benefit Base is increased to the Anniversary Value, the MAWA will be
recalculated on that Benefit Year anniversary, by multiplying the new Benefit
Base by the applicable MAWP.

IMPACT OF WITHDRAWALS
Withdrawals reduce the amount available for Withdrawal under the GMWB. Total
Withdrawals in any Benefit Year equal to or less than the MAWA reduce the
Benefit Base by the amount of the Withdrawal. Once Withdrawals in a Benefit Year
exceed the MAWA, all subsequent Withdrawals in that Benefit Year are Excess
Withdrawals. Excess Withdrawals may reduce the Benefit Base based on the
relative size of the Withdrawal in relation to the Contract Value at the time of
the Excess Withdrawal. This means that when the Contract Value is less than the
Benefit Base, Excess Withdrawals will result in a reduction of the Benefit Base
which is greater than the amount of the Excess Withdrawal. We further explain
this impact and the effect on each component of the GMWB through the
calculations below:

WITHDRAWALS IMPACT CONTRACT VALUE AND THE COMPONENTS OF THE GMWB CALCULATION AS
FOLLOWS:

    1.  CONTRACT VALUE:  Any Withdrawal reduces the Contract Value by the amount
        of the Withdrawal.

    2.  BENEFIT BASE:  Withdrawals up to the MAWA, before any Excess Withdrawal,
        reduce the Benefit Base by the dollar amount of the Withdrawal.

        Any Excess Withdrawal further reduces the Benefit Base to the lesser
        of (a) or (b), where:

               (a) is the Benefit Base immediately prior to the Excess
                   Withdrawal minus the amount of the Excess Withdrawal, or;

               (b) is the Benefit Base immediately prior to the Excess
                   Withdrawal reduced in the same proportion by which the
                   Contract Value is reduced by the Excess Withdrawal.

    3.  MINIMUM WITHDRAWAL PERIOD: If the total of all Withdrawals in a
        Benefit Year are less than or equal to the MAWA, the new MWP equals the
        Benefit Base after the Withdrawal divided by the current MAWA. When the
        Benefit Base is adjusted to a higher Anniversary Value, a new MWP is
        determined by dividing the new Benefit Base by the new MAWA.

        If there is an Excess Withdrawal in a Benefit Year, the new MWP equals
        the MWP calculated at the end of the prior Benefit Year reduced by one
        year.

    4.  MAXIMUM ANNUAL WITHDRAWAL AMOUNT: If there are no Excess Withdrawals in
        a Benefit Year, the MAWA does not change for the next Benefit Year,
        unless the Benefit Base is increased as described above under "Benefit
        Base."

        If there are any Excess Withdrawals in a Benefit Year, the MAWA will be
        recalculated on the next Benefit Year anniversary. The new MAWA will
        equal the new Benefit Base on that Benefit Year anniversary after the

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<PAGE>

        Withdrawal divided by the new Minimum Withdrawal Period on that Benefit
        Year anniversary. The new MAWA may be lower than Your previously
        calculated MAWA.

IF YOUR CONTRACT VALUE IS REDUCED TO ZERO
If Your Contract Value is reduced to zero and the Benefit Base is greater than
zero, subsequent Purchase Payments will no longer be accepted and a Death
Benefit will not be payable. You can receive the remaining value of the GMWB
under one of the following options:

    a.  A lump sum equal to the discounted present value of any remaining
        guaranteed payments under the GMWB; or,

    b.  Periodic payments during each Benefit Year that in total are equal to
        the MAWA until the Benefit Base has been reduced to zero. If You do not
        select a specific frequency for these payments, We will pay the current
        MAWA in quarterly payments; or,

    c.  Any payment option that is mutually agreeable.

EXTENSION OF THE BENEFIT BASE EVALUATION PERIOD ("EXTENSION")
We may offer You at least one Extension of the Benefit Base Evaluation Period at
the end of the current Benefit Base Evaluation Period. If You elect such
Extension, you will receive a new endorsement with the charges and provisions in
effect at that time.

TERMINATION OF THE GMWB

Once elected the GMWB Endorsement and its corresponding charge may be terminated
by the Owner. If the Owner's request to terminate the GMWB is received:

    1.  prior to the 5th Benefit Year anniversary, the termination is effective
        on the 5th Benefit Year anniversary;

    2.  after the 5th, but prior to the 10th Benefit Year anniversary, the
        termination is effective on the 10th Benefit Year anniversary;

    3.  in any Benefit Year after the 10th Benefit Year anniversary, the
        termination is effective on the Benefit Year anniversary following Our
        receipt of the election to terminate the GMWB.

The Endorsement and the related charge will terminate automatically if:

    1.  The Benefit Base has been reduced to zero; or,

    2.  A Spousal Beneficiary elects to continue the Contract without this
        Endorsement; or,

    3.  A Death Benefit is paid (as described under the Death Provisions or
        Death Benefit section of Your Contract); or,

    4.  The Contract is fully withdrawn or surrendered; or,

    5.  The Contract is annuitized.

We reserve the right to terminate the GMWB Endorsement if Withdrawals in excess
of the MAWA in any Benefit Year reduce the Benefit Base by 50% or more.

If terminated, the GWMB may not be re-elected.

SPOUSAL CONTINUATION
Upon election to continue the Contract and this Endorsement, Your Spousal
Beneficiary will be subject to the terms and conditions of this Endorsement. The
Effective Date will not change as the result of Spousal Continuation. A
continuation contribution paid under the Spousal Continuation provision of the
Contract is not considered an Eligible Purchase Payment, but is included in the
calculation of Anniversary Values if the spouse continues the Benefit Base
Evaluation Period.

Signed for the Company to be effective on the Effective Date.

AIG SUNAMERICA LIFE ASSURANCE COMPANY

    /s/ CHRISTINE A. NIXON                     /s/ JANA W. GREER
-------------------------------         -------------------------------
      Christine A. Nixon                         Jana W. Greer
           Secretary                               President

                                       4exv10w1

 

Exhibit 10.1

INDEMNIFICATION AGREEMENT

     This
Indemnification Agreement (the “Agreement”), is dated as of                     , 20___ between
Genomic Health, Inc., a Delaware corporation (the “Corporation”), and                      (“Indemnitee”).

W I T N E S S E T H:

     WHEREAS, Indemnitee is either a member of the board of directors of the Corporation (the
“Board of Directors”) or an officer of the Corporation, or both, and in such capacity or
capacities, or otherwise as an Agent (as hereinafter defined) of the Corporation, is performing a
valuable service for the Corporation; and

     WHEREAS, the Corporation is aware that competent and experienced persons are increasingly
reluctant to serve as directors or officers of corporations unless they are protected by
comprehensive indemnification and liability insurance, due to increased exposure to litigation
costs and risks resulting from their service to such corporations, and because the exposure
frequently bears no reasonable relationship to the compensation of such directors and officers; and

     WHEREAS, the Board of Directors of the Corporation has concluded that, to retain and attract
talented and experienced individuals to serve or continue to serve as officers or directors of the
Corporation, and to encourage such individuals to take the business risks necessary for the success
of the Corporation, it is necessary for the Corporation contractually to indemnify directors and
officers and to assume for itself to the fullest extent permitted by law expenses and damages in
connection with claims against such officers and directors in connection with their service to the
Corporation; and

     WHEREAS, Section 145 of the General Corporation Law of Delaware, under which the Corporation
is organized (the “DGCL”), empowers the Corporation to indemnify by agreement its officers,
directors, employees and agents, and persons who serve, at the request of the Corporation, as
directors, officers, employees or agents of other corporations or enterprises, and expressly
provides that the indemnification provided by the DGCL is not exclusive; and

     WHEREAS, the Corporation desires and has requested the Indemnitee to serve or continue to
serve as a director, officer or agent of the Corporation free from undue concern for claims for
damages arising out of or related to such services to the Corporation; and

     WHEREAS, Indemnitee is willing to serve, continue to serve and to take on additional service
for or on behalf of the Corporation on the condition that he or she be indemnified as herein
provided; and

     WHEREAS, it is intended that Indemnitee shall be paid promptly by the Corporation all amounts
necessary to effectuate in full the indemnity provided herein:

 

 

     NOW, THEREFORE, in consideration of the premises and the covenants in this Agreement, and of
Indemnitee serving or continuing to serve the Corporation as an Agent and intending to be legally
bound hereby, the parties hereto agree as follows:

     1. Services by Indemnitee. Indemnitee agrees to serve or continue to serve (a) as a
director or an officer of the Corporation, or both, so long as Indemnitee is duly appointed or
elected and qualified in accordance with the applicable provisions of the Certificate of
Incorporation and bylaws of the Corporation, and until such time as Indemnitee resigns or fails to
stand for election or is removed from Indemnitee’s position, or (b) otherwise as an Agent of the
Corporation. Indemnitee may from time to time also perform other services at the request or for
the convenience of, or otherwise benefiting the Corporation. Indemnitee may at any time and for
any reason resign or be removed from such position (subject to any other contractual obligation or
other obligation imposed by operation of law), in which event the Corporation shall have no
obligation under this Agreement to continue Indemnitee in any such position.

     2. Indemnification of Indemnitee. Subject to the limitations set forth herein and
particularly in Section 6 hereof, the Corporation hereby agrees to indemnify Indemnitee as follows:

     (a) The Corporation shall, with respect to any Proceeding (as hereinafter defined) associated
with Indemnitee’s being an Agent of the Corporation, indemnify Indemnitee to the fullest extent
permitted by applicable law or as such law may from time to time be amended (but, in the case of
any such amendment, only to the extent such amendment permits the Corporation to provide broader
indemnification rights than the law permitted the Corporation to provide before such amendment).
The right to indemnification conferred herein shall be presumed to have been relied upon by
Indemnitee in serving or continuing to serve the Corporation as an Agent and shall be enforceable
as a contract right. Without in any way diminishing the scope of the indemnification provided by
this Section 2(a), the rights of indemnification of Indemnitee shall include but shall not be
limited to those rights hereinafter set forth.

     (b) The Corporation shall indemnify Indemnitee if Indemnitee is or was a party or is
threatened to be made a party to any threatened, pending or completed Proceeding (other than an
action by or in the right of the Corporation) by reason of the fact that Indemnitee is or was an
Agent of the Corporation, or any subsidiary of the Corporation, or by reason of the fact that
Indemnitee is or was serving at the request of the Corporation as an Agent of another corporation,
partnership, joint venture, trust or other enterprise, against Expenses (as hereinafter defined) or
Liabilities (as hereinafter defined), actually and reasonably incurred by Indemnitee in connection
with such Proceeding if Indemnitee acted in good faith and in a manner Indemnitee reasonably
believed to be in or not opposed to the best interests of the Corporation, and, with respect to any
criminal action or proceeding, had no reasonable cause to believe Indemnitee’s conduct was
unlawful.

     (c) The Corporation shall indemnify Indemnitee if Indemnitee was or is a party or is
threatened to be made a party to any threatened, pending or completed Proceeding by or in the
right of the Corporation or any subsidiary of the Corporation to procure a judgment in its
favor by reason of the fact that Indemnitee is or was an Agent of the Corporation, or any
subsidiary of the Corporation, or by reason of the fact that Indemnitee is or was serving at the
request of the

2

 

Corporation as an Agent of another corporation, partnership, joint venture, trust or
other enterprise, against Expenses and, to the fullest extent permitted by law, Liabilities if
Indemnitee acted in good faith and in a manner Indemnitee reasonably believed to be in or not
opposed to the best interests of the Corporation, except that no indemnification shall be made in
respect of any claim, issue or matter as to which Indemnitee shall have been adjudged to be liable
to the Corporation unless and only to the extent that the Court of Chancery of the State of
Delaware or the court in which such action or suit was brought shall determine upon application
that, despite the adjudication of liability but in view of all the circumstances of the case,
Indemnitee is fairly and reasonably entitled to indemnity for such expenses which the Court of
Chancery of the State of Delaware or such other court shall deem proper.

     3. Advancement of Expenses. All reasonable Expenses incurred by or on behalf of
Indemnitee (including costs of enforcement of this Agreement) shall be advanced from time to time
by the Corporation to Indemnitee within thirty (30) days after the receipt by the Corporation of a
written request for an advance of Expenses, whether prior to or after final disposition of a
Proceeding (except to the extent that there has been a Final Adverse Determination (as hereinafter
defined) that Indemnitee is not entitled to be indemnified for such Expenses), including without
limitation any Proceeding brought by or in the right of the Corporation. The written request for
an advancement of any and all Expenses under this paragraph shall contain reasonable detail of the
Expenses incurred by Indemnitee. In the event that such written request shall be accompanied by an
affidavit of counsel to Indemnitee to the effect that such counsel has reviewed such Expenses and
that such Expenses are reasonable in such counsel’s view, then such expenses shall be deemed
reasonable in the absence of clear and convincing evidence to the contrary. By execution of this
Agreement, Indemnitee shall be deemed to have made whatever undertaking as may be required by law
at the time of any advancement of Expenses with respect to repayment to the Corporation of such
Expenses. In the event that the Corporation shall breach its obligation to advance Expenses under
this Section 3, the parties hereto agree that Indemnitee’s remedies available at law would not be
adequate and that Indemnitee would be entitled to specific performance.

     4. Presumptions and Effect of Certain Proceedings. Upon making a request for
indemnification, Indemnitee shall be presumed to be entitled to indemnification under this
Agreement and the Corporation shall have the burden of proof to overcome that presumption in
reaching any contrary determination. The termination of any Proceeding by judgment, order,
settlement, arbitration award or conviction, or upon a plea of nolo contendere or its equivalent
shall not affect this presumption or, except as determined by a judgment or other final
adjudication adverse to Indemnitee, establish a presumption with regard to any factual matter
relevant to determining Indemnitee’s rights to indemnification hereunder. If the person or persons
so empowered to make a determination pursuant to Section 5 hereof shall have failed to make the
requested determination within sixty (60) days after any judgment, order, settlement, dismissal,
arbitration award, conviction, acceptance of a plea of nolo contendere or its equivalent, or other
disposition or partial disposition of any Proceeding or any
other event that could enable the Corporation to determine Indemnitee’s entitlement to
indemnification, the requisite determination that Indemnitee is entitled to indemnification shall
be deemed to have been made.

3

 

     5. Procedure for Determination of Entitlement to Indemnification.

     (a) Whenever Indemnitee believes that Indemnitee is entitled to indemnification pursuant to
this Agreement, Indemnitee shall submit a written request for indemnification to the Corporation.
Any request for indemnification shall include sufficient documentation or information reasonably
available to Indemnitee for the determination of entitlement to indemnification. In any event,
Indemnitee shall submit Indemnitee’s claim for indemnification within a reasonable time, not to
exceed five (5) years after any judgment, order, settlement, dismissal, arbitration award,
conviction, acceptance of a plea of nolo contendere or its equivalent, or final determination,
whichever is the later date for which Indemnitee requests indemnification. The Secretary or other
appropriate officer shall, promptly upon receipt of Indemnitee’s request for indemnification,
advise the Board of Directors in writing that Indemnitee has made such request. Determination of
Indemnitee’s entitlement to indemnification shall be made not later than sixty (60) days after the
Corporation’s receipt of Indemnitee’s written request for such indemnification, provided that any
request for indemnification for Liabilities, other than amounts paid in settlement, shall have been
made after a determination thereof in a Proceeding. If it is so determined that the Indemnitee is
entitled to indemnification, payment to the Indemnitee shall be made within ten (10) days after
such determination.

     (b) The Corporation shall be entitled to select the forum in which Indemnitee’s entitlement to
indemnification will be heard; provided, however, that if there is a Change in Control of the
Corporation, Independent Legal Counsel (as hereinafter defined) shall determine whether Indemnitee
is entitled to indemnification. The forum shall be any one of the following:

     (i) a majority vote of Disinterested Directors (as hereinafter defined), even though
less than a quorum;

     (ii) by a committee of Disinterested Directors designated by majority vote of
Disinterested Directors, even though less than a quorum;

     (iii) Independent Legal Counsel, whose determination shall be made in a written
opinion; or

     (iv) the stockholders of the Corporation.

     6. Specific Limitations on Indemnification. Notwithstanding anything in this Agreement to the contrary, the Corporation shall not be
obligated under this Agreement to make any payment to Indemnitee with respect to any Proceeding:

     (a) To the extent that payment is actually made to Indemnitee under any insurance policy, or
is made to Indemnitee by the Corporation or an affiliate otherwise than pursuant to this Agreement.
Notwithstanding the availability of such insurance, Indemnitee also may claim indemnification from
the Corporation pursuant to this Agreement by assigning to the Corporation any claims under such
insurance to the extent Indemnitee is paid by the Corporation;

4

 

     (b) Provided there has been no Change in Control, for Liabilities in connection with
Proceedings settled without the Corporation’s consent, which consent, however, shall not be
unreasonably withheld;

     (c) For an accounting of profits made from the purchase or sale by Indemnitee of securities of
the Corporation within the meaning of Section 16(b) of the Securities Exchange Act of 1934, as
amended (the “Exchange Act”), or similar provisions of any state statutory or common law;

     (d) To the extent it would be otherwise prohibited by law, if so established by a judgment or
other final adjudication adverse to Indemnitee; or

     (e) In connection with a Proceeding commenced by Indemnitee (other than a Proceeding commenced
by Indemnitee to enforce Indemnitee’s rights under this Agreement) unless the commencement of such
Proceeding was authorized by the Board of Directors.

     7. Fees and Expenses of Independent Legal Counsel or Arbitrators. The Corporation
agrees to pay the reasonable fees and expenses of Independent Legal Counsel should such Independent
Legal Counsel be retained to make a determination of Indemnitee’s entitlement to indemnification
pursuant to Section 5(b) of this Agreement, and to fully indemnify such Independent Legal Counsel
against any and all expenses and losses incurred by any of them arising out of or relating to this
Agreement or their engagement pursuant hereto.

     8. Remedies of Indemnitee.

     (a) In the event that (i) a determination pursuant to Section 5 hereof is made that Indemnitee
is not entitled to indemnification, (ii) advances of Expenses are not made pursuant to this
Agreement, (iii) payment has not been timely made following a determination of entitlement to
indemnification pursuant to this Agreement, or (iv) Indemnitee otherwise seeks enforcement of this
Agreement, Indemnitee shall be entitled to a final adjudication in the Court of Chancery of the
State of Delaware of the remedy sought. Alternatively, unless court approval is required by law
for the indemnification sought by Indemnitee, Indemnitee at Indemnitee’s option may seek an award
in arbitration to be conducted by a single arbitrator pursuant to the commercial arbitration rules
of the American Arbitration Association now in effect, which award is to be
made within ninety (90) days following the filing of the demand for arbitration. The
Corporation shall not oppose Indemnitee’s right to seek any such adjudication or arbitration award.
In any such proceeding or arbitration Indemnitee shall be presumed to be entitled to
indemnification and advancement of Expenses under this Agreement and the Corporation shall have the
burden of proof to overcome that presumption.

     (b) In the event that a determination that Indemnitee is not entitled to indemnification, in
whole or in part, has been made pursuant to Section 5 hereof, the decision in the judicial
proceeding or arbitration provided in paragraph (a) of this Section 8 shall be made de novo and
Indemnitee shall not be prejudiced by reason of a determination that Indemnitee is not entitled to
indemnification.

     (c) If a determination that Indemnitee is entitled to indemnification has been made pursuant
to Section 5 hereof, or is deemed to have been made pursuant to Section 4 hereof or

5

 

otherwise pursuant to the terms of this Agreement, the Corporation shall be bound by such determination.

     (d) The Corporation shall be precluded from asserting that the procedures and presumptions of
this Agreement are not valid, binding and enforceable. The Corporation shall stipulate in any such
court or before any such arbitrator that the Corporation is bound by all the provisions of this
Agreement and is precluded from making any assertion to the contrary.

     (e) Expenses reasonably incurred by Indemnitee in connection with Indemnitee’s request for
indemnification under, seeking enforcement of or to recover damages for breach of this Agreement
shall be borne by the Corporation when and as incurred by Indemnitee irrespective of any Final
Adverse Determination that Indemnitee is not entitled to indemnification.

     9. Contribution. To the fullest extent permissible under applicable law, if the
indemnification provided for in this Agreement is unavailable to Indemnitee for any reason
whatsoever, the Corporation, in lieu of indemnifying Indemnitee, shall contribute to the amount
incurred by Indemnitee, whether for judgments, fines, penalties, excise taxes, amounts paid or to
be paid in settlement and/or for Expenses, in connection with any claim relating to an
indemnifiable event under this Agreement, in such proportion as is deemed fair and reasonable in
light of all of the circumstances of such Proceeding in order to reflect (i) the relative benefits
received by the Corporation and Indemnitee as a result of the event(s) and/or transaction(s) giving
cause to such Proceeding; and/or (ii) the relative fault of the Corporation (and its directors,
officers, employees and agents) and Indemnitee in connection with such event(s) and/or
transaction(s).

     10. Maintenance of Insurance. The Corporation represents that it presently has in
place certain directors’ and officers’ liability insurance policies covering its directors and
officers. Subject only to the provisions within this Section 10, the Corporation agrees that so
long as Indemnitee shall have consented to serve or shall continue to serve as a director or
officer of the Corporation, or both, or as an Agent of the Corporation, and thereafter so long as
Indemnitee shall be subject to any possible Proceeding (such periods being hereinafter sometimes
referred to as the “Indemnification
Period”), the Corporation will use all reasonable efforts to maintain in effect for the
benefit of Indemnitee one or more valid, binding and enforceable policies of directors’ and
officers’ liability insurance from established and reputable insurers, providing, in all respects,
coverage both in scope and amount which is no less favorable than that presently provided.
Notwithstanding the foregoing, the Corporation shall not be required to maintain said policies of
directors’ and officers’ liability insurance during any time period if during such period such
insurance is not reasonably available or if it is determined in good faith by the then directors of
the Corporation either that:

     (i) The premium cost of maintaining such insurance is substantially disproportionate to
the amount of coverage provided thereunder; or

     (ii) The protection provided by such insurance is so limited by exclusions, deductions
or otherwise that there is insufficient benefit to warrant the cost of maintaining such
insurance.

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     Anything in this Agreement to the contrary notwithstanding, to the extent that and for so long
as the Corporation shall choose to continue to maintain any policies of directors’ and officers’
liability insurance during the Indemnification Period, the Corporation shall maintain similar and
equivalent insurance for the benefit of Indemnitee during the Indemnification Period (unless such
insurance shall be less favorable to Indemnitee than the Corporation’s existing policies).

     11. Modification, Waiver, Termination and Cancellation. No supplement, modification,
termination, cancellation or amendment of this Agreement shall be binding unless executed in
writing by both of the parties hereto. No waiver of any of the provisions of this Agreement shall
be deemed or shall constitute a waiver of any other provisions hereof (whether or not similar), nor
shall such waiver constitute a continuing waiver.

     12. Subrogation. In the event of payment under this Agreement, the Corporation shall
be subrogated to the extent of such payment to all of the rights of recovery of Indemnitee, who
shall execute all papers required and shall do everything that may be necessary to secure such
rights, including the execution of such documents necessary to enable the Corporation effectively
to bring suit to enforce such rights.

     13. Notice by Indemnitee and Defense of Claim. Indemnitee shall promptly notify the
Corporation in writing upon being served with any summons, citation, subpoena, complaint,
indictment, information or other document relating to any matter, whether civil, criminal,
administrative or investigative, but the omission so to notify the Corporation will not relieve it
from any liability that it may have to Indemnitee if such omission does not prejudice the
Corporation’s rights. If such omission does prejudice the Corporation’s rights, the Corporation
will be relieved from liability only to the extent of such prejudice. Notwithstanding the
foregoing, such omission will not relieve the Corporation from
any liability that it may have to Indemnitee otherwise than under this Agreement. With
respect to any Proceeding as to which Indemnitee notifies the Corporation of the commencement
thereof:

     (a) The Corporation will be entitled to participate therein at its own expense; and

     (b) The Corporation jointly with any other indemnifying party similarly notified will be
entitled to assume the defense thereof, with counsel reasonably satisfactory to Indemnitee;
provided, however, that the Corporation shall not be entitled to assume the defense of any
Proceeding if there has been a Change in Control or if Indemnitee shall have reasonably concluded
that there may be a conflict of interest between the Corporation and Indemnitee with respect to
such Proceeding. After notice from the Corporation to Indemnitee of its election to assume the
defense thereof, the Corporation will not be liable to Indemnitee under this Agreement for any
Expenses subsequently incurred by Indemnitee in connection with the defense thereof, other than
reasonable costs of investigation or as otherwise provided below. Indemnitee shall have the right
to employ Indemnitee’s own counsel in such Proceeding, but the fees and expenses of such counsel
incurred after notice from the Corporation of its assumption of the defense thereof shall be at the
expense of Indemnitee unless:

     (i) the employment of counsel by Indemnitee has been authorized by the Corporation;

7

 

     (ii) Indemnitee shall have reasonably concluded that counsel engaged by the Corporation
may not adequately represent Indemnitee due to, among other things, actual or potential
differing interests; or

     (iii) the Corporation shall not in fact have employed counsel to assume the defense in
such Proceeding or shall not in fact have assumed such defense and be acting in connection
therewith with reasonable diligence; in each of which cases the fees and expenses of such
counsel shall be at the expense of the Corporation.

     (c) The Corporation shall not settle any Proceeding in any manner that would impose any
penalty or limitation on Indemnitee without Indemnitee’s written consent; provided, however, that
Indemnitee will not unreasonably withhold his or her consent to any proposed settlement.

     14. Notices. All notices, requests, demands and other communications hereunder shall
be in writing and shall be deemed to have been duly given if (i) delivered by hand and receipted
for by the party to whom said notice or other communication shall have been directed, or (ii)
mailed by certified or registered mail with postage prepaid, on the third business day after the
date on which it is so mailed:

	 	(a)	 	If to Indemnitee, to:
	 
	 	 	 	                                                            
	 
	 	 	 	                                                            
	 
	 	 	 	                                                            
	 
	 	 	 	                                                            
	 
	 	(b)	 	If to the Corporation, to:

Genomic Health, Inc.

301 Penobscot Drive

Redwood City, CA 94063

Attn: Secretary

or to such other address as may have been furnished to Indemnitee by the Corporation or to the
Corporation by Indemnitee, as the case may be.

     15. Nonexclusivity. The rights of Indemnitee hereunder shall not be deemed exclusive
of any other rights to which Indemnitee may be entitled under applicable law, the Corporation’s
Certificate of Incorporation or bylaws, or any agreements, vote of stockholders, resolution of the
Board of Directors or otherwise, and to the extent that during the Indemnification Period the
rights of the then existing directors and officers are more favorable to such directors or officers
than the rights currently provided to Indemnitee thereunder or under this Agreement, Indemnitee
shall be entitled to the full benefits of such more favorable rights.

     16. Certain Definitions.

     (a) “Agent” shall mean any person who is or was, or who has consented to serve as, a
director, officer, employee, agent, fiduciary, joint venturer, partner, manager or other official
of the Corporation or a subsidiary or an affiliate of the Corporation, or any other entity
(including without limitation, an employee benefit plan) either at the request of, for the
convenience of, or

8

 

otherwise to benefit the Corporation or a subsidiary of the Corporation. Any
person who is or was serving as a director, officer, employee or agent of a subsidiary of the
Corporation shall be deemed to be serving, or have served, at the request of the Corporation.

     (b) “Change in Control” shall mean the occurrence of any of the following:

     (i) Both (A) any “person” (as defined below) is or becomes the “beneficial owner” (as
defined in Rule 13d-3 under the Exchange Act), directly or indirectly, of securities of the
Corporation representing at least twenty percent (20%) of the total voting power represented
by the Corporation’s then outstanding voting securities and (B) the beneficial ownership by
such person of securities representing such percentage is not approved by a majority of the
“continuing directors” (as defined below);

     (ii) Any “person” is or becomes the “beneficial owner” (as defined in Rule 13d-3 under
the Exchange Act), directly or indirectly, of securities of the Corporation representing at
least fifty percent (50%) of the total voting power represented by the Corporation’s then
outstanding voting securities;

     (iii) A change in the composition of the Board of Directors occurs, as a result of
which fewer than two-thirds of the incumbent directors are directors who either (A) had been
directors of the Corporation on the “look-back date” (as defined below) (the
“Original Directors”) or (B) were elected, or nominated for election, to the Board of
Directors with the affirmative votes of at least a majority in the aggregate of the Original
Directors who were still in office at the time of the election or nomination and directors
whose election or nomination was previously so approved (the “continuing directors”);

     (iv) The stockholders of the Corporation approve a merger or consolidation of the
Corporation with any other corporation, if such merger or consolidation would result in the
voting securities of the Corporation outstanding immediately prior thereto representing
(either by remaining outstanding or by being converted into voting securities of the
surviving entity) 50% or less of the total voting power represented by the voting securities
of the Corporation or such surviving entity outstanding immediately after such merger or
consolidation; or

     (v) The stockholders of the Corporation approve (A) a plan of complete liquidation of
the Corporation or (B) an agreement for the sale or disposition by the Corporation of all or
substantially all of the Corporation’s assets.

     For purposes of Subsections (i) and (ii) above, the term “person” shall have the same meaning
as when used in Sections 13(d) and 14(d) of the Exchange Act, but shall exclude (x) a trustee or
other fiduciary holding securities under an employee benefit plan of the Corporation or of a parent
or subsidiary of the Corporation or (y) a corporation owned directly or indirectly by the
stockholders of the Corporation in substantially the same proportions as their ownership of the
common stock of the Corporation.

     For purposes of Subsection (iii) above, the term “look-back date” shall mean the later of (x)
the date first written above in the preamble to this Agreement or (y) the date 24 months prior to
the date of the event that may constitute a “Change in Control.”

9

 

     Any other provision of this Section 16(b) notwithstanding, the term “Change in Control” shall
not include a transaction, if undertaken at the election of the Corporation, the result of which is
to sell all or substantially all of the assets of the Corporation to another corporation (the
“surviving corporation”); provided that the surviving corporation is owned directly or indirectly
by the stockholders of the Corporation immediately following such transaction in substantially the
same proportions as their ownership of the Corporation’s common stock immediately preceding such
transaction; and provided, further, that the surviving corporation expressly assumes this
Agreement.

     (c) “Disinterested Director” shall mean a director of the Corporation who is not or
was not a party to the Proceeding in respect of which indemnification is being sought by
Indemnitee.

     (d) “Expenses” shall include all direct and indirect costs (including, without
limitation, attorneys’ fees, retainers, court costs, transcripts, fees of experts, witness fees,
travel expenses, duplicating costs, printing and binding costs, telephone charges, postage,
delivery service fees, all other disbursements or out-of-pocket expenses and reasonable
compensation for time spent by Indemnitee for which Indemnitee is otherwise not compensated by the
Corporation or any third party) actually and reasonably incurred in connection with either the
investigation, defense, settlement or appeal of a Proceeding or establishing or enforcing a right
to indemnification under
this Agreement, applicable law or otherwise; provided, however, that “Expenses” shall not
include any Liabilities.

     (e) “Final Adverse Determination” shall mean that a determination that Indemnitee is
not entitled to indemnification shall have been made pursuant to Section 5 hereof and either (1) a
final adjudication in the Court of Chancery of the State of Delaware or decision of an arbitrator
pursuant to Section 8(a) hereof shall have denied Indemnitee’s right to indemnification hereunder,
or (2) Indemnitee shall have failed to file a complaint in a Delaware court or seek an arbitrator’s
award pursuant to Section 8(a) for a period of one hundred twenty (120) days after the
determination made pursuant to Section 5 hereof.

     (f) “Independent Legal Counsel” shall mean a law firm or a member of a firm selected
by the Corporation and approved by Indemnitee (which approval shall not be unreasonably withheld)
or, if there has been a Change in Control, selected by Indemnitee and approved by the Corporation
(which approval shall not be unreasonably withheld), that neither is presently nor in the past five
(5) years has been retained to represent: (i) the Corporation or any of its subsidiaries or
affiliates, or Indemnitee or any corporation of which Indemnitee was or is a director, officer,
employee or agent, or any subsidiary or affiliate of such a corporation, in any material matter, or
(ii) any other party to the Proceeding giving rise to a claim for indemnification hereunder.
Notwithstanding the foregoing, the term “Independent Legal Counsel” shall not include any person
who, under the applicable standards of professional conduct then prevailing, would have a conflict
of interest in representing either the Corporation or Indemnitee in an action to determine
Indemnitee’s right to indemnification under this Agreement.

     (g) “Liabilities” shall mean liabilities of any type whatsoever including, but not
limited to, any judgments, fines, ERISA excise taxes and penalties, penalties and amounts paid in
settlement (including all interest assessments and other charges paid or payable in connection

10

 

with or in respect of such judgments, fines, penalties or amounts paid in settlement) of any Proceeding.

     (h) “Proceeding” shall mean any threatened, pending or completed action, claim, suit,
arbitration, alternate dispute resolution mechanism, investigation, administrative hearing or any
other proceeding whether civil, criminal, administrative or investigative, that is associated with
Indemnitee’s being an Agent of the Corporation.

     17. Binding Effect; Duration and Scope of Agreement. This Agreement shall be binding
upon the parties hereto and their respective successors and assigns (including any direct or
indirect successor by purchase, merger, consolidation or otherwise to all or substantially all of
the business or assets of the Corporation), spouses, heirs and personal and legal representatives.
This Agreement shall be deemed to be effective as of the commencement date of the Indemnitee’s
service as an officer or director of the Corporation and shall continue in effect during the
Indemnification Period, regardless of whether Indemnitee continues to serve as an Agent.

     18. Severability. If any provision or provisions of this Agreement (or any portion thereof) shall be held to
be invalid, illegal or unenforceable for any reason whatsoever:

     (a) the validity, legality and enforceability of the remaining provisions of this Agreement
shall not in any way be affected or impaired thereby; and

     (b) to the fullest extent legally possible, the provisions of this Agreement shall be
construed so as to give effect to the intent of any provision held invalid, illegal or
unenforceable.

     19. Governing Law. This Agreement shall be governed by and construed and enforced in
accordance with the laws of the State of Delaware, as applied to contracts between Delaware
residents entered into and to be performed entirely within the State of Delaware, without regard to
conflict of laws rules.

     20. Consent to Jurisdiction. The Corporation and Indemnitee each irrevocably consent
to the jurisdiction of the courts of the State of Delaware for all purposes in connection with any
action or proceeding that arises out of or relates to this Agreement and agree that any action
instituted under this Agreement shall be brought only in the state courts of the State of Delaware.

     21. Entire Agreement. This Agreement represents the entire agreement between the
parties hereto, and there are no other agreements, contracts or understandings between the parties
hereto with respect to the subject matter of this Agreement, except as specifically referred to
herein or as provided in Section 15 hereof.

11

 

     22. Counterparts. This Agreement may be executed in one or more counterparts, each of
which shall for all purposes be deemed to be an original but all of which together shall constitute
one and the same Agreement.

     IN WITNESS WHEREOF, the Corporation has caused this Agreement to be executed by a duly
authorized officer and Indemnitee has executed this Agreement as of the date first above written.

	 	 	 	 	 	 	 
	 	 	GENOMIC HEALTH, INC., a Delaware corporation	 	 
	 
	 	 	 	 	 	 
	 

	 	By	 	 	 	 
	 

	 	 	 	 	 	 
	 
	 	 	 	 	 	 
	 	 	INDEMNITEE	 	 
	 
	 	 	 	 	 	 
	 	 	 	 	 

12

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