Document:

Exhibit
4.1

 

AMENDMENT
NO. 2 TO WARRANT AND PUT OPTION AGREEMENT

 

This AMENDMENT NO. 2 (the “Second
Amendment”) to the WARRANT AND PUT OPTION AGREEMENT (the “Agreement”)
originally dated as of November 30, 2006, by and between Gian Luigi Buitoni.
(the “Lead Investor”) and Xenomics, Inc. (the “Company”), as amended August 29,
2007 is dated as of October 30, 2007.

WITNESSETH:

 

 

                WHEREAS, on November 30, 2006,
the Lead Investor and the Company entered into the Agreement and amended such
Agreement on August 29, 2007; and

 

                WHEREAS, the parties now desire
to amend Section 3(b) of such Agreement in order to preserve the Company’s
right to exercise the Maximum Put Amount in December 2007;

 

                NOW, THEREFORE, in consideration
of and for the mutual promises and covenants contained herein, and for other
good and valuable consideration, the receipt of which is hereby acknowledged,
the Agreement is hereby amended as follows:

 

                1.             The last sentence of the definition of “Maximum Put
Amount” in Section 3(b)(i) is hereby replaced in its entirety with “In no event
shall the Maximum Put Amount exceed $1,500,000.”

 

                2.             Section 3(b)(ii) shall be replaced in its entirety with
the following:

 

                                “In
the event the Financing Condition has not been met, upon written
notice from the Company on February 26, 2008 (the “Put Closing Date”), by
February 27, 2008, the Lead Investor shall purchase the number of Units
specified in such notice up to the Maximum Put Amount divided by the applicable
Exercise Price.  On the Put Closing Date, the Lead Investor shall
surrender this Warrant and the full Exercise Price of the Units specified in
the Notice in immediately available funds against the Company’s delivery of
Lead Investor’s Securities.  If less than all of the Investor’s Securities
which may then be acquired on the exercise of this Warrant are specified in the
Notice, the Company shall cancel this Warrant and issue and deliver to the Lead
Investor a new Warrant for the Lead Investor’s Securities remaining.”

 

                3.             (A)          This
Second Amendment shall be construed and interpret­ed in accordance with the
laws of the State of New York without giving effect to the conflict of laws
rules thereof or the actual domiciles of the parties.

 

                                (B)           Except as amended hereby, the terms
and provisions of the Agreement shall remain in full force and effect, and the
Agreement is in all respects ratified and confirmed. On and after the date of
this Second Amendment, each reference in the Agreement to the “Agree-

 

 

 

 

ment”,
“hereinafter”, “herein”, “hereinafter”, “hereunder”, “hereof”, or words of like
import shall mean and be a reference to the Agreement as amended by this Second
Amendment.

 

                                (C)           This Second Amendment may be executed
in one or more counter­parts, each of which shall be deemed an original and all
of which taken together shall constitute a single Amendment.

 

                IN WITNESS WHEREOF, the parties hereto have executed
this Second Amendment as of the date first stated above.

 

 

	
   

  	
   

  	
  LEAD INVESTOR

  
	
   

  	
   

  	
   

  	
   

  
	
   

  	
   

  	
  By:

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
  Gianluigi
  Longinotti-Buitoni

  
	
   

  	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
  XENOMICS, INC.

  
	
   

  	
   

  	
   

  	
   

  
	
   

  	
   

  	
  By:

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
  Name:
  Gianluigi Longinotti-Buitoni

  
	
   

  	
   

  	
   

  	
  Title:
  Executive Chairman

  
						

 

 

 

 

2Exhibit 10.1

 

TWENTY-FOURTH
AMENDMENT

TO

SECOND AMENDED AND RESTATED

LIMITED PARTNERSHIP
AGREEMENT

OF

CORPORATE OFFICE PROPERTIES, L.P.

 

This Twenty-Fourth
Amendment (the Amendment) to the Second Amended and Restated Limited
Partnership Agreement Of Corporate Office Properties, L.P., a Delaware limited
partnership (the Partnership), is made and entered into as of November 2, 2007,
by the undersigned.

 

Recitals

 

A.            The Partnership is a limited
partnership organized under the Delaware Revised Uniform Limited Partnership
Act and governed by that certain Second Amended and Restated Limited
Partnership Agreement dated as of December 7, 1999, as amended to the date
hereof (as amended, the “Partnership Agreement”).

 

B.            The sole general partner of the
Partnership is Corporate Office Properties Trust, a real estate investment
trust formed under the laws of the State of Maryland (the “General Partner”).

 

C.            Pursuant to Section 11.1 (b) (iii),
the General Partner desires to amend the Partnership Agreement to reflect the
admission, substitution, termination and/or withdrawal of various limited
partners in accordance with the terms of the Partnership Agreement.

 

NOW THEREFORE,
the General Partner, intending to be legally bound, hereby amends the
Partnership Agreement as follows, effective as of the date first set forth
above.

 

1.                                       Exhibit
1, Schedule of Partners, as attached hereto and by this reference made a part
hereof, is hereby substituted for and intended to replace any prior Exhibit 1
attached to a prior Amendment to the Partnership Agreement, and as attached
hereto shall be a full and complete listing of all the general and limited
partners of the Partnership as of the date of this Amendment, same being
intended and hereby superceding all prior Exhibit 1 listings.

 

In Witness
Whereof, the General Partner has executed this Amendment as of the day and year
first above written.

 

	
   

  	
  Corporate
  Office Properties Trust, a

  
	
   

  	
  Maryland
  Real Estate Investment Trust

  
	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
  By:

  	
      /s/
  Roger A. Waesche, Jr.

  	
   

  
	
   

  	
   

  	
      Roger
  A. Waesche, Jr.

  
	
   

  	
   

  	
      Executive
  Vice President

  

 

 

Exhibit 1
Addendum

 

Schedule of Partners

 

	
  General Partner

  	
   

  	
  Common Units of Partnership Units

  	
   

  	
  Series G

  Preferred

  Units

  	
   

  	
  Series H

  Preferred

  Units

  	
   

  	
  Series I

  Preferred

  Units

  	
   

  	
  Series J

  Preferred

  Units

  	
   

  	
  Series K

  Preferred

  Units

  	
   

  
	
  Corporate Office Properties Trust

  	
   

  	
  45,281,754

  	
   

  	
  2,200,000

  	
   

  	
  2,000,000

  	
   

  	
   

  	
   

  	
  3,390,000

  	
   

  	
  531,667

  	
   

  
	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Limited Partners and Preferred Limited
  Partners

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Jay H. Shidler

  	
   

  	
  452,878

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Shidler Equities, L.P.

  	
   

  	
  2,995,439

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Clay W. Hamlin, III

  	
   

  	
  396,317

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  LBCW Limited Partnership

  	
   

  	
  2,681,107

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Robert L. Denton

  	
   

  	
  400,000

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  James K. Davis

  	
   

  	
  51,589

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  John E. De B. Blockey, Trustee of the John
  E. de B. Blockey Living Trust dated 9/12/88

  	
   

  	
  300,625

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Frederick K. Ito Trust

  	
   

  	
  20,340

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  June Y. I. Ito Trust

  	
   

  	
  20,335

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  RP Investments, LLC

  	
   

  	
  50,000

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Denise J. Liszewski

  	
   

  	
  14,333

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Samuel Tang

  	
   

  	
  4,389

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Lawrence J. Taff

  	
   

  	
  13,733

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Kimberly F. Aquino

  	
   

  	
  2,937

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  M.O.R. 44 Gateway Associates Limited
  Partnership

  	
   

  	
  1

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  John Parsinen

  	
   

  	
  49,434

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  M.O.R. Commons Limited Partnership

  	
   

  	
  7

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  John Edward De Burgh Blockey and Sanda
  Juanita Blockey

  	
   

  	
  10,476

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Lynn Hamlin

  	
   

  	
  121,411

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Housing Affiliates, Inc.

  	
   

  	
  4,402

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Reingle Corp.

  	
   

  	
  730

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Joseph Tawil

  	
   

  	
  2,160

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  The Lovejoy Trust

  	
   

  	
  59,528

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  The Century Trust

  	
   

  	
  59,528

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  A. Charles Wilson & Betty S. Wilson
  Trust

  	
   

  	
  5,908

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Harold & Renee Holland

  	
   

  	
  4,320

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Irwin Hoffman

  	
   

  	
  1,880

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Rouse 1988 Trust

  	
   

  	
  2,160

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  CB Management, L.L.C.

  	
   

  	
  2,497

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Patriot Partner, L.L.C.

  	
   

  	
  25,000

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Lawrence G. Rief

  	
   

  	
  2,526

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  David D. Jenkins

  	
   

  	
  262,165

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  RA & DM, Inc.

  	
   

  	
  2,954

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Bernard Manekin

  	
   

  	
  16,514

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Estate of Harold Manekin

  	
   

  	
  15,242

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Richard Alter

  	
   

  	
  43,817

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Donald Manekin

  	
   

  	
  23,336

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  William Winstead

  	
   

  	
  14,019

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Richard Manekin

  	
   

  	
  8,988

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Robert Manekin

  	
   

  	
  8,988

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Charles Manekin

  	
   

  	
  3,899

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Vivian Manekin

  	
   

  	
  880

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Francine Manekin

  	
   

  	
  880

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Sandye Sirota

  	
   

  	
  5,427

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Lynn Stern

  	
   

  	
  880

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Louis LaPenna

  	
   

  	
  2,513

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Jamie Deutsch

  	
   

  	
  22

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  Kelly Alter

  	
   

  	
  22

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  TRC Associates Limited Partnership

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
  352,000

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
   

  	
   

  	
  53,447,990

  	
   

  	
  2,200,000

  	
   

  	
  2,000,000

  	
   

  	
  352,000

  	
   

  	
  3,390,000

  	
   

  	
  531,667

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00131-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00131-of-00352.parquet"}]]