Document:

EX-10.2

 Exhibit 10.2 

AMENDMENT NO. 1 TO EMPLOYMENT AGREEMENT 

This Amendment No. 1 to Employment Agreement (the “Amendment”) is entered into as of August 7, 2014 by and between
OXiGENE, Inc., a Delaware corporation, (the “Company”), and Dr. David Chaplin, an individual (the “Executive”). 

W I T N E S S E T H : 

WHEREAS, the Company and the Executive are parties to an Employment Agreement dated May 16, 2014 (the “Employment Agreement”);
and 
 WHEREAS, the Company and the Executive desire to amend the Employment Agreement to provide Executive with additional benefits and to
correct the terms of the Agreement relating to options to be granted to the Executive; 
 NOW, THEREFORE, in consideration of the mutual
covenants contained herein and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Employment Agreement is amended as follows: 

1. Section 3.3 of the Agreement is hereby deleted and replaced in its entirety with the following: 

“3.3 The Company shall grant to Executive, subject to approval by the Compensation Committee of the Board, options to purchase one
hundred fifty thousand (150,000) shares of the Company’s common stock at an exercise price equal to the fair market value of such stock on the date of grant pursuant to and in accordance with the terms of the Company’s 2005 Stock
Plan, as amended (the “Stock Plan”) and the Company’s standard form of option agreement within 60 days of Executive’s first day of employment. The options will be non-qualified options. The options shall vest as follows:
(a) 25% of the options will vest on the first anniversary of the date of grant, and (b) the remaining 75% will vest in substantially equal monthly installments over the next 36 months following such first anniversary, such that the option
is 100% vested as of the fourth anniversary of the date of grant. In addition, Executive shall be eligible to receive stock option grants, stock bonuses, restricted stock grants or other equity compensation awards granted to Executive from time to
time by the Board in its sole discretion and to participate in any equity compensation plan that may be established by the Company for Executive or its executive team generally.” 

2. Section 4 of the Agreement is amended by adding the following sentence after the last sentence in the Section. 

“In addition, the Company shall (i) reimburse Executive or pay on his behalf the costs of furnished housing in San Francisco,
inclusive of utilities, and the retention of a rental car, and (ii) reimburse Executive or pay on his behalf the cost of one, business class roundtrip ticket between San Francisco and London per month.” 

 3. Section 7.1(b) of the Agreement is hereby deleted in its entirety and replaced with the
following: 
 “(b) to the extent required by law and the Company’s written vacation policy, an amount equal to the value of the
Executive’s accrued but unused vacation days, calculated at a rate of $1,576.92 per day.” 
 4. Section 7.2 of the Agreement
is hereby amended by adding the following new sub-clause (d): 
 “(d) the Gross Up (as defined in Section 8), for the calendar
year in which the termination of employment occurs.” 
 5. Section 7.3 of the Agreement is hereby amended by adding the following
new sub-clause (e): 
 “(e) the Gross Up for the calendar year in which the termination of employment occurs.” 

6. Section 7.4 of the Agreement is hereby deleted and replaced in its entirety with the following: 

“7.4 The payments described in Sections 7.2(b), (c) and (d), and Sections 7.3(b), (c), (d) and (e), shall be paid or commence
to be paid within ninety (90) days of Executive’s termination of employment, provided that prior to the expiration of the ninety (90) day period, Executive has delivered to the Company a general release of claims in a form determined
by the Company and the release has become enforceable and irrevocable. If the ninety (90) day period begins in one tax year and ends in the following tax year, the payments will commence in the following tax year. In all cases, the first
payment will include all amounts that would have been paid to Executive under Sections 7.2(b), (c) and (d), and Sections 7.3(b), (c), (d) and (e), between the date the termination of Executive’s employment became effective and the
first payment date.” 
 7. The paragraph in Section 8 (titled “Taxes”) of the Agreement is hereby deleted and replaced
in its entirety with the following: 
 “Any amounts or benefits payable or provided to Executive under this Agreement shall be paid or
provided to Executive subject to all applicable taxes required to be withheld by the Company pursuant to relevant federal, state and/or local law. Executive shall be solely responsible for all taxes imposed on Executive by reason of his receipt of
any amounts of compensation or benefits payable hereunder. The Company makes no representation, warranty or promise regarding the tax treatment of any 

 
payment or benefit provided to Executive. Notwithstanding the foregoing, to the extent that the provision of any in-kind benefit or reimbursement by the Company of any of Executive’s living
or travel expenses constitute taxable income (the “Taxable Benefits”) to the Executive under the laws of the United States, then the Company shall pay to the Executive an amount (the “Gross Up”) to compensate the Executive for
the economic cost of the federal, state and local income and payroll taxes payable with respect to the Taxable Benefits. The calculation of the amount of the Gross Up shall insure that, after payment by the Executive of the federal, state and local
income and payroll taxes with respect to the Taxable Benefits and the Gross Up, the Executive will be in substantially the same economic position after all taxes as if the Taxable Benefits were not includable in income. For purposes of determining
the amount of the Gross Up, the Executive shall be deemed to pay federal, state and local income and payroll taxes at the highest marginal rate of taxation in the calendar year in which Executive received the Taxable Benefits. The Gross Up will be
paid no later than December 31 of the year in which the Executive received the Taxable Benefits. Except as otherwise provided for in this Agreement, Executive must be employed as of the payment date in order to receive the Gross Up.” 

8. The parties expressly acknowledge and agree that this Amendment constitutes a modification of the Employment Agreement by written agreement
executed by the parties, as permitted by Section 11 of the Employment Agreement. 
 9. Except as specifically modified herein, the
terms of the Employment Agreement shall remain in full force and effect. It is understood and agreed that this Amendment to the Employment Agreement shall become part of the Employment Agreement and shall be a binding agreement upon execution by the
parties. 
 [Signature Page to Follow] 

 IN WITNESS WHEREOF, OXiGENE and Executive have caused this Amendment to be executed as of the
date first above written. 
  

									
	OXiGENE, INC.	 		 	DR. DAVID CHAPLIN
				
	By:	 	 /s/ Frederick W. Driscoll
	 		 	 /s/ Dr. David Chaplin

		 	Name:	 	Frederick W. Driscoll	 		 	
		 	Title:	 	Chairman of the BoardEX-10.3

 Exhibit 10.3 

SEPARATION AGREEMENT AND RELEASE 

THIS SEPARATION AGREEMENT AND RELEASE (“Agreement”) is made and entered into by and between Dr. Peter J. Langecker
(“Employee”) and OXiGENE, Inc. (“Company”), and inures to the benefit of each of Company’s current, former and future, as applicable, parents, subsidiaries, affiliates, related entities, employee benefit plans and their
fiduciaries, predecessors, successors, officers, directors, shareholders, agents, insurers, counsel, employees and assigns. The term “Parties” used in this Agreement means Company and Employee collectively. 

RECITALS 
  

A. Employee was an at-will employee of Company; 

B. Employee separated from Company effective May 15, 2014 (the “Separation Date”); and 

C. The Parties want to resolve any and all actual or potential disputes arising out of or relating to Employee’s employment with Company
or the cessation of that employment. 
 Company and Employee agree as follows: 

1. Severance Benefit. In consideration of the covenants and releases in this Agreement, Company will: (a) pay Employee a
severance benefit of $386,250.00 (equivalent to one year of his gross annual base salary effective as of the Separation Date), less withholdings authorized or required by law, in accordance with Company’s normal payroll cycle, commencing on the
first payroll cycle after the Effective Date of this Agreement; and (b) reimburse for 12 months, starting the month immediately after the Effective Date, Employee’s monthly COBRA premiums, subject to applicable laws and requirements and
Employee’s eligibility and compliance with COBRA and insurance requirements. After the 12 months, Company will no longer pay or reimburse Employee for any COBRA or other health insurance premiums. However, if Employee obtains other health
insurance coverage from another employer, company, or business entity within the 12 months after the Effective Date, Company will no longer be required to pay for or reimburse Employee for COBRA. Employee is required to inform Company immediately
after Employee learns he will be covered by other health insurance and when that coverage begins. Collectively Sections 1(a)-(b) are the “Severance Benefit”. Employee must comply with all of the terms of this Agreement, and his
Employee Proprietary Information and Assignment of Inventions Agreement (“Confidentiality Agreement”) in order to receive, or continue to receive, the Severance Benefit. Employee acknowledges and agrees that but for his agreement to enter
into, and provide the releases in, this Agreement, he is not entitled to the Severance Benefit. Employee further acknowledges and agrees that the Severance Benefit does not constitute, in any way, any sort of severance plan. 

2. Wages and Vacation Time Paid. Employee acknowledges that Company paid Employee, on the Separation Date, all of
Employee’s wages due and owing, and paid for any unused vacation, accrued through the Separation Date. Employee acknowledges that he has 

 
received all other wages or compensation that Company owes him. Additionally, Employee acknowledges that Company has reimbursed him for all Company business expenses he has incurred up through
the Separation Date. Employee’s receipt of these wages, accrued benefits, and reimbursements was not conditioned upon the execution of this Agreement. 

3. Health Benefits. Company provided Employee with health insurance during his employment with Company. If Employee wants to
continue his health insurance coverage, he acknowledges he must do so through COBRA. Except as set forth above in Section 1, Company will not be paying for or reimbursing Employee for any health insurance costs or premiums (COBRA) after his
separation from Company. 
 4. Reference Requests. If contacted by prospective employers, Company will release information
concerning only the dates of Employee’s employment and the last position held. Company will inform prospective employers that it is Company policy to release only this information. 

5. Release and Waiver by Employee. Employee, on behalf of himself and his heirs, executors, administrators, assigns and
successors, fully and forever releases and discharges Company, and, as applicable, its current, former and future parents, subsidiaries, and related entities, employee benefit plans and fiduciaries, predecessors, successors, officers, directors,
shareholders, agents, insurers, counsel, employees and assigns (collectively, “Releasees”), from any and all claims, liabilities and causes of action, of every nature, kind and description, in law, equity or otherwise, which have arisen,
occurred or existed at any time prior to his signing of this Agreement, including, without limitation, any and all claims, liabilities and causes of action arising out of or relating to Employee’s employment with Company or the cessation of
that employment. 
 6. Waiver of Employment-Related Claims. Employee waives and releases, except the potential claims
identified below, all rights, remedies, or claims he may have had or now has against Company or any of the Releasees regarding employment-related causes of action, that are applicable to Employee and Company and to which Company is subject,
including without limitation, claims of wrongful discharge, breach of contract, retaliation, breach of the covenant of good faith and fair dealing, fraud, violation of public policy, claims that he is or was a “whistleblower,” defamation,
discrimination, personal injury, physical injury, emotional distress, claims under Title VII of the Civil Rights Act of 1964, the Americans With Disabilities Act, Age Discrimination in Employment Act of 1967, the Older Workers Benefit Protection Act
of 1990, the Federal Rehabilitation Act, the California Fair Employment and Housing Act, the California Family Rights Act, the Equal Pay Act of 1963, the provisions of the California Labor Code and any other federal, state or local laws and
regulations relating to employment, conditions of employment (including wage and hour laws) and/or employment discrimination. Claims not covered by the Employee’s waiver and release are: (a) claims for unemployment insurance benefits,
(b) claims under California’s Workers Compensation laws, (c) claims relating to the Company’s express obligations under this Agreement, and (d) claims that cannot be waived or released as a matter of law (including, without
limitation, administrative claims before the United States Equal Employment Opportunity Commission (“EEOC”), including Employee testifying, assisting or participating in an investigation or proceeding by the EEOC or any comparable state or
local agency). Employee represents and warrants that he does not believe he 

 
currently has any work related injuries. Employee’s waiver and release, however, are intended to be a complete bar to any recovery or personal benefit by or to Employee regarding any claim
(except those which cannot be released under law), including those raised through a charge with the EEOC. Accordingly, nothing in this section will be deemed to limit Company’s right to seek immediate dismissal of the charge or complaint on the
basis that Employee’s signing of this Agreement constitutes a full release of any individual rights under the federal discrimination laws, or to seek restitution to the extent permitted by law of the economic benefits provided to Employee under
this Agreement in the event Employee successfully challenges the validity of this release and prevails in any claim under the federal discrimination laws. 

7. Waiver of Unknown Claims. In executing this Agreement, Employee waives and relinquishes all rights and benefits granted to
Employee under the provisions of Section 1542 of the California Civil Code or any similar statute or doctrine. Civil Code section 1542 provides as follows: 

A general release does not extend to claims which the creditor does not know or suspect to exist in his or her favor at the time of
executing the release, which if known by him or her must have materially affected his or her settlement with the debtor. 
 Employee
acknowledges that he has read all of this Agreement, including the above Civil Code section, and that both the general release and Employee’s release of all rights and benefits pursuant to Civil Code section 1542 are fully understood. In
waiving the provisions of Section 1542 of the California Civil Code, Employee acknowledges that he may later discover facts in addition to or different from those which he now believes to be true with respect to the matters released in this
Agreement. But, he agrees that he has taken that possibility into account in reaching this Agreement, and that the releases in this Agreement will remain in effect as full and complete releases notwithstanding the discovery or existence of
additional or different facts. 
 8. Severability. If a Court rules that any provision in this Agreement is unenforceable, it
will not affect the enforceability of the remaining provisions. The Court may enforce all remaining provisions to the extent permitted by law. 

9. Confidentiality of Agreement. The Parties will not disclose to others, and will keep confidential, unless compelled by legal
process or other legal requirements, including without limitation the Company’s compliance with its obligations under the U.S. securities laws, both the fact of and terms of this Agreement. The Parties may disclose this information to
attorneys, accountants and other professional advisors to whom the disclosure is necessary to accomplish the purposes for which these professional advisors were retained. Employee may disclose the terms of this Agreement to his spouse/family if they
agree in advance to keep this Agreement and its terms confidential. The Parties may disclose the terms of this Agreement as necessary to enforce its terms or to remedy for the breach of its terms. Employee acknowledges that keeping confidential the
fact and terms of this Agreement is a material provision of this Agreement, and the breach of this provision will relieve Company of its obligation to pay or continue to pay the Severance Benefit and will allow Company to seek recovery of any
amounts paid to Employee under this Agreement, subject to applicable laws. 

 10. Confidential Information. Employee acknowledges that, as a condition to his
employment with Company, he executed the Confidentiality Agreement. This Agreement in no way affects, alters or waives Employee’s obligations or Company’s rights under the Confidentiality Agreement (together with its attached exhibits).
Employee’s ongoing compliance with the Confidentiality Agreement is a material condition to this Agreement, and an express condition to Employee’s receipt of the Severance Benefit described in this Agreement. 

11. Non-Disparagement. Employee agrees not to disparage, in any manner, Company, its parents, successors, sister companies,
divisions or affiliates; provided, however, that Employee may respond accurately and fully to any question, inquiry or request for information when required by legal process. Company’s officers and directors will not disparage Employee
in any manner; provided, however, that Company and its officers and directors may respond accurately and fully to any question, inquiry or request for information when required by legal process. 

12. Cooperation. Employee agrees to cooperate fully with Company in connection with any internal or external investigation, in
the defense or prosecution of any claims or actions now in existence or which may be brought in the future (whether before or after the Separation Date) against or on behalf of Company or its affiliates, and to assist Company in responding to
requests for information or documents from any governmental authority, relating to events or occurrences that transpired during Employee’s employment with Company. This cooperation will include Employee assisting Company with the current FINRA
investigation regarding or relating to Company’s announcement of certain clinical trial results. Employee’s full cooperation will include, but not be limited to, meeting with representatives of Company and/or meeting with Company counsel
(and providing truthful responses to any questions by Company or its counsel), cooperating in discovery, providing affidavits and testimony as may be required or deemed necessary by Company, and informing Company of any requests by any third party
for Employee’s testimony or information or documents in Employee’s possession. 
 13. Return of Company Property. In
order to receive the Severance Benefit, Employee must return all Company property in Employee’s possession, custody or control no later than five (5) business days after the Separation Date. 

14. Integrated Agreement. This Agreement (together with the agreements and documents to which it specifically refers) contains
the entire agreement of the Parties concerning its subject matter. The Parties did not make any promises or representations to each other that do not appear in this Agreement. This Agreement supersedes all other agreements between the Parties
excluding the Confidentiality Agreement. 
 15. Voluntary Execution. Employee has read and understands this Agreement.
Employee voluntarily signs this Agreement. No person coerced Employee to sign this Agreement. Even if any of the facts or matters upon which Employee relied in making this Agreement prove to be otherwise, this Agreement will remain in full force and
effect. 

 16. Waiver, Amendment and Modification. No waiver, amendment or modification of
this Agreement’s terms is effective unless it is in writing and signed by all parties affected by the waiver, amendment or modification. The Parties’ waiver of any term or condition of this Agreement will not be construed as a waiver of
any other term or condition. 
 17. Counterparts. This Agreement may be signed in counterparts and those counterparts will be
treated as if they were one signed document. 
 18. Employee’s Right To Release. Employee warrants and represents that
(a) Employee has not assigned or transferred, or purported to assign or transfer, and that Employee will not in the future assign or transfer to any person or entity, any right or claim released by this Agreement, any part thereof, or any
interest therein, and (b) Employee is the sole owner of the rights and claims released in this Agreement. 
 19. Venue and
Governing Law. The validity, interpretation, enforceability, and performance of this Agreement must be governed by and construed in accordance with the laws of the State of California, exclusive of its choice-of-law rules. Any action arising
under or relating to this Agreement must be commenced and maintained in the federal or state courts as applicable in San Francisco County, California. The parties agree to the personal jurisdiction of these Courts in San Francisco County. 

20. Tax Liability. Employee assumes full responsibility for any and all taxes, interest and/or penalties that may be assessed
upon the Severance Benefit. 
 21. Consideration/Revocation Period. This Agreement is intended to release and discharge any
claims by Employee under the Age Discrimination in Employment Act. To satisfy the requirements of the Older Workers’ Benefit Protection Act, 29 U.S.C. section 626(f), as applicable: 

 

	 	(a)	Employee acknowledges that he has read and understands the terms of this Agreement. 

  

	 	(b)	Employee acknowledges that he has been advised to consult with independent counsel regarding this Agreement, and that he has received all counsel necessary to willingly and knowingly enter into this Agreement.

  

	 	(c)	Employee understands that in signing this Agreement, Employee is not waiving rights or claims based on matters occurring after the date this Agreement is executed. 

 

	 	(d)	Employee understands and agrees that Employee is waiving rights on claims only in exchange for consideration that Employee was not already entitled to. 

 

	 	(e)	Employee understands that this Agreement does not prohibit Employee from challenging or seeking a determination in good faith of the validity of this release or waiver under the Age Discrimination in Employment Act and
does not impose any condition precedent, penalty, or costs for doing so unless specifically authorized by federal law. 

	 	(f)	Employee acknowledges that he has been given twenty-one (21) days to consider the terms of this Agreement (the “Consideration Period”), has taken sufficient time to consider whether to execute it, and has
chosen to enter into this Agreement knowingly and voluntarily. If Employee does not present an executed copy of this Agreement to the Company’s Chief Financial Officer before the expiration of the Consideration Period, this Agreement and the
offer it contains will lapse. 

  

	 	(g)	During the seven (7) days after the execution of this Agreement (should he elect to execute it), Employee may revoke this Agreement by delivering a written revocation (via facsimile, email or personal delivery) to
the Company’s Chief Financial Officer. This Agreement will not become effective until the eighth (8th) day after Employee executes and does not revoke it (the “Effective Date”). If Employee either fails to sign the Agreement
during the Consideration Period, or revokes it prior to the Effective Date, he will not receive and/or be entitled to the Severance Benefit described in this Agreement. 

IN WITNESS WHEREOF, the Parties have executed this Agreement as of the dates written below. 

 

					
	Dated: May 16, 2014	 		 	 /s/ Dr. Peter J. Langecker

		 		 	DR. PETER J. LANGECKER
			
		 		 	OXIGENE, INC.
			
	Dated: May 16, 2014	 		 	 /s/ Frederick W. Driscoll

		 		 	By: FREDERICK W. DRISCOLL
		 		 	Chairman of the Board of Directors

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