Document:

EX-10.5

EXHIBIT 10.5

SECOND AMENDMENT TO PROMISSORY NOTE

THIS SECOND AMENDMENT (THE “SECOND AMENDMENT”) DATED JULY 27, 2015, SHALL AMEND THE PROMISSORY
NOTE (THE “NOTE”) DATED AS OF FEBRUARY 22, 2013 AND AMENDED ON JULY 31, 2013 (“THE
FIRST AMENDMENT”) AMONG NON-INVASIVE MONITORING SYSTEMS, INC. (THE “MAKER”) AND JANE HSIAO (THE
“PAYEE”) AS NOTED BELOW. THE NOTE, THE FIRST AMENDMENT, AND SECOND AMENDMENT SHALL BE REFERRED TO
AS THE AMENDED NOTE.

RECITALS

WHEREAS, Maker and Payee (collectively, the “Parties”) are parties to the Note which became
effective on February 22, 2013;

WHEREAS, on July 31, 2013, the Parties amended the Note to extend the Maturity Date from
September 12, 2014 until July 31, 2015; and

WHEREAS, the Parties wish to extend the Maturity Date from July 31, 2015 to July 31, 2017.

NOW THEREFORE, in consideration of the mutual covenants and promises contained in the Note and
this Second Amendment and other good and valuable consideration, the receipt and sufficiency of
which are hereby acknowledged, the Parties agree as follows:

AMENDMENT

	 	1.	 	Section 1 of the Note is hereby amended and restated in its entirety as
follows:

The principal amount of the loan evidenced hereby, together with any accrued and
unpaid interest, and any and all unpaid costs, fees and expenses accrued, shall be
due and payable on July 31, 2017 (the “Maturity Date”).

2. Governing Law. This Second Amendment shall be governed by the laws of the State of Florida
without regard to its conflict of laws rules or principles.

3. Amendments. Except as expressly amended hereby, the Note shall remain unmodified and in
full force and effect.

4. Entire Agreement. This Second Amendment and the Amended Note constitute the entire
agreement of the Parties with respect to the subject matter hereof and supersede all prior
understandings and writings between the Parties relating thereto.

5. Interpretation. Any capitalized terms used in this Second Amendment but not otherwise
defined shall have the meaning provided in the Note.

6. Counterparts. This Second Amendment may be executed manually, electronically in Adobe® PDF
file format, or by facsimile by the Parties, in any number of counterparts, each of which shall be
considered one and the same amendment and shall become effective when a counterpart hereof shall
have been signed by each of the Parties and delivered to the other Party.

IN WITNESS WHEREOF, Borrower has duly executed this Second Amendment to the Note and Security
Note as of the 27th day of July, 2015.

	 	 	 
	 	 	NON-INVASIVE MONITORING SYSTEMS, INC.
	
 
	 	By: /s/ James J. Martin
	
 
	 	 
	
 
	 	Name: James J. Martin

Title: Chief Financial Officer
	Agreed and Accepted:

	 	

	By: /s/ Jane Hsiao

	 	

	 

	 	

	Name: Jane Hsiao, Ph.D.EX-10.6

EXHIBIT 10.6

FIRST AMENDMENT TO PROMISSORY NOTE

THIS FIRST AMENDMENT (THE “FIRST AMENDMENT”) DATED JULY 27, 2015, SHALL AMEND THE PROMISSORY
NOTE (THE “NOTE”) DATED AS OF SEPTEMBER 24, 2014 AMONG NON-INVASIVE MONITORING SYSTEMS, INC. (THE
“MAKER”) AND JANE HSIAO (THE “PAYEE”) AS NOTED BELOW.

RECITALS

WHEREAS, Maker and Payee (collectively, the “Parties”) are parties to the Note which became
effective on September 24, 2014; and

WHEREAS, the Parties desire to amend the Note to extend the Maturity Date from July 31, 2015
until July 31, 2017.

NOW THEREFORE, in consideration of the mutual covenants and promises contained in the Note and
this First Amendment and other good and valuable consideration, the receipt and sufficiency of
which are hereby acknowledged, the Parties agree as follows:

AMENDMENT

	 	1.	 	Section 1 of the Note is hereby amended and restated in its entirety as
follows:

The principal amount of the loan evidenced hereby, together with any accrued and
unpaid interest, and any and all unpaid costs, fees and expenses accrued, shall be
due and payable on July 31, 2017 (the “Maturity Date”).

2. Governing Law. This First Amendment shall be governed by the laws of the State of Florida
without regard to its conflict of laws rules or principles.

3. Amendments. Except as expressly amended hereby, the Note shall remain unmodified and in
full force and effect.

4. Entire Agreement. This First Amendment and the Note constitute the entire agreement of the
Parties with respect to the subject matter hereof and supersede all prior understandings and
writings between the Parties relating thereto.

5. Interpretation. Any capitalized terms used in this First Amendment but not otherwise
defined shall have the meaning provided in the Note.

6. Counterparts. This First Amendment may be executed manually, electronically in Adobe® PDF
file format, or by facsimile by the Parties, in any number of counterparts, each of which shall be
considered one and the same amendment and shall become effective when a counterpart hereof shall
have been signed by each of the Parties and delivered to the other Party.

IN WITNESS WHEREOF, Borrower has duly executed this First Amendment to the Note and Security
Note as of the 27th day of July, 2015.

	 	 	 
	 	 	NON-INVASIVE MONITORING SYSTEMS, INC.
	
 
	 	By: /s/ James J. Martin
	
 
	 	 
	
 
	 	Name: James J. Martin

Title: Chief Financial Officer
	Agreed and Accepted:

	 	

	By: /s/       Jane Hsiao—

	 	

	 

	 	

	Name: Jane Hsiao, Ph.D.EX-10.7

EXHIBIT 10.7

FIRST AMENDMENT TO PROMISSORY NOTE

THIS FIRST AMENDMENT (THE “FIRST AMENDMENT”) DATED JULY 27, 2015, SHALL AMEND THE PROMISSORY
NOTE (THE “NOTE”) DATED AS OF FEBRUARY 2, 2015 AMONG NON-INVASIVE MONITORING SYSTEMS, INC. (THE
“MAKER”) AND JANE HSIAO (THE “PAYEE”) AS NOTED BELOW.

RECITALS

WHEREAS, Maker and Payee (collectively, the “Parties”) are parties to the Note which became
effective on February 2, 2015; and

WHEREAS, the Parties desire to amend the Note to extend the Maturity Date from July 31, 2015
until July 31, 2017.

NOW THEREFORE, in consideration of the mutual covenants and promises contained in the Note and
this First Amendment and other good and valuable consideration, the receipt and sufficiency of
which are hereby acknowledged, the Parties agree as follows:

AMENDMENT

	 	1.	 	Section 1 of the Note is hereby amended and restated in its entirety as
follows:

The principal amount of the loan evidenced hereby, together with any accrued and
unpaid interest, and any and all unpaid costs, fees and expenses accrued, shall be
due and payable on July 31, 2017 (the “Maturity Date”).

2. Governing Law. This First Amendment shall be governed by the laws of the State of Florida
without regard to its conflict of laws rules or principles.

3. Amendments. Except as expressly amended hereby, the Note shall remain unmodified and in
full force and effect.

4. Entire Agreement. This First Amendment and the Note constitute the entire agreement of the
Parties with respect to the subject matter hereof and supersede all prior understandings and
writings between the Parties relating thereto.

5. Interpretation. Any capitalized terms used in this First Amendment but not otherwise
defined shall have the meaning provided in the Note.

6. Counterparts. This First Amendment may be executed manually, electronically in Adobe® PDF
file format, or by facsimile by the Parties, in any number of counterparts, each of which shall be
considered one and the same amendment and shall become effective when a counterpart hereof shall
have been signed by each of the Parties and delivered to the other Party.

IN WITNESS WHEREOF, Borrower has duly executed this First Amendment to the Note and Security
Note as of the 27th day of July, 2015.

	 	 	 
	 	 	NON-INVASIVE MONITORING SYSTEMS, INC.
	
 
	 	By: /s/ James J. Martin
	
 
	 	 
	
 
	 	Name: James J. Martin

Title: Chief Financial Officer
	Agreed and Accepted:

	 	

	By: /s/       Jane Hsiao—

	 	

	 

	 	

	Name: Jane Hsiao, Ph.D.EX-10.8

EXHIBIT 10.8

FIRST AMENDMENT TO PROMISSORY NOTE

THIS FIRST AMENDMENT (THE “FIRST AMENDMENT”) DATED JULY 27, 2015, SHALL AMEND THE PROMISSORY
NOTE (THE “NOTE”) DATED AS OF APRIL 16, 2015 AMONG NON-INVASIVE MONITORING SYSTEMS, INC. (THE
“MAKER”) AND FROST GAMMA INVESTMENTS TRUST (THE “PAYEE”) AS NOTED BELOW.

RECITALS

WHEREAS, Maker and Payee (collectively, the “Parties”) are parties to the Note which became
effective on April 16, 2015; and

WHEREAS, the Parties desire to amend the Note to extend the Maturity Date from July 31, 2015
until July 31, 2017.

NOW THEREFORE, in consideration of the mutual covenants and promises contained in the Note and
this First Amendment and other good and valuable consideration, the receipt and sufficiency of
which are hereby acknowledged, the Parties agree as follows:

AMENDMENT

	 	1.	 	Section 1 of the Note is hereby amended and restated in its entirety as
follows:

The principal amount of the loan evidenced hereby, together with any accrued and
unpaid interest, and any and all unpaid costs, fees and expenses accrued, shall be
due and payable on July 31, 2017 (the “Maturity Date”).

2. Governing Law. This First Amendment shall be governed by the laws of the State of Florida
without regard to its conflict of laws rules or principles.

3. Amendments. Except as expressly amended hereby, the Note shall remain unmodified and in
full force and effect.

4. Entire Agreement. This First Amendment and the Note constitute the entire agreement of the
Parties with respect to the subject matter hereof and supersede all prior understandings and
writings between the Parties relating thereto.

5. Interpretation. Any capitalized terms used in this First Amendment but not otherwise
defined shall have the meaning provided in the Note.

6. Counterparts. This First Amendment may be executed manually, electronically in Adobe® PDF
file format, or by facsimile by the Parties, in any number of counterparts, each of which shall be
considered one and the same amendment and shall become effective when a counterpart hereof shall
have been signed by each of the Parties and delivered to the other Party.

IN WITNESS WHEREOF, Borrower has duly executed this First Amendment to the Note and Security
Note as of the 27th day of July, 2015.

	 	 	 
	 	 	NON-INVASIVE MONITORING SYSTEMS,
	 	 	INC.
	
 
	 	By: /s/ James J. Martin
	
 
	 	 
	
 
	 	Name: James J. Martin

Title: Chief Financial Officer
	Agreed and Accepted:

	 	

	FROST GAMMA INVESTMENTS TRUST

	 	

	By: /s/       Phillip Frost—

	 	

	 

	 	

	Name: Phillip Frost, M.D.

Title: Trustee

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00247-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00247-of-00352.parquet"}], [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00247-of-00352.parquet"}], [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00247-of-00352.parquet"}]]