Document:

Ex 10.10

Exhibit 10.10  Employment Agreement with David Moskowitz

                              EMPLOYMENT AGREEMENT

        Agreement made as of 10 August, 2001 by and between Monopath, LLC, a
Delaware corporation (the "Company"), having its principal place of business at
4560 Clayton Ave. St. Louis, Missouri 63110, and David Moskowitz (the
"Executive") currently residing at 518 Bonhomme Woods Drive, St. Louis, Missouri
63132-3403.

BACKGROUND INFORMATION
The Company wishes to secure the employment services of the Executive for a
definite period of time and upon the particular terms and conditions hereinafter
set forth. The Executive is willing to be so employed. Accordingly, the parties
agree as follows:

        1. Employment and Term.
The Company hereby employs Executive and the latter hereby accepts employment by
the Company for the five (5) year period commencing on 15 August, 2001 (the
"Commencement Date") and expiring 15 August, 2003, which employment shall be
automatically extended for unlimited successive one (1) year periods unless it
is terminated during the pendency of any such period, whether initial or
extended, by the occurrence of one of the events described in Section 8. hereof,
or at the end of any such period (subject to extension by operation of the
disability provisions contained in Section 8.) by one party furnishing the other
with written notice, at least sixty' (60) days prior to the expiration of such
period, of any intent to tem1inate this Agreement upon the expiration or such
period.

        2.  Duties
During the term of this Agreement, whether initial or extended, the Executive
shall render to the Company services as President, Chief Executive Officer,
Chief Scientific Officer, and Chairman of the Board of Directors/Managers and
shall perform such duties as may be designated by and subject to the supervision
of the Company's Board of Directors/Managers, and shall serve in such additional
capacities appropriate to his responsibilities and skills as shall be designated
by the Company, through action of its Board of Directors/Managers. During such
period, the Executive shall devote his full attention, time and energies to the
business affairs of the Company (subject to the terms of Section 4. below), and
will use his best efforts to promote the Interests and reputation of the
Company; provided that he may pursue such non-competitive activities during
weekdays and on weekends, such as teaching, entertaining, consulting or other
remunerative or non-remunerative affairs, as do not interfere, to any degree,
with the complete performance of his obligations hereunder. Any question of
interpretation which may arise under the preceding provision shall be resolved
by majority decision of the Company's Board of Directors/Managers. Hours of
service to the Company during the term of this Agreement shall be a minimum of
forty (40) per week and otherwise as determined by the Company's Board of
Directors/Managers. During the pendency of this Agreement, without his written
consent, the Company shall not remove the Executive's permanent place of
business from St. Louis, Missouri.

                                       1

         3. Compensation
 For the services to be rendered by the Executive under this Agreement, the
Company shall pay him, while he is rendering such services and performing his
duties hereunder, and the Executive shall accept as full payment for such
service, a base compensation of one hundred and thirty-five thousand dollars
($135,000.00) per year, (inclusive of any amounts subject to federal or state
employment related withholding requirements), payable in arrears in equal
installments on the last business day of each week occurring during the period
of employment or otherwise as the parties may agree. Such base compensation may
be periodically increased on any anniversary of the Commencement Date to take
into account superior performance or increases, if any, in the annual cost of
living, and may at such time be supplemented by discretionary bonuses or other
benefits payable from time to time, all as determined by action of the Company's
Board of Directors/Managers. Executive shall also be entitled to a Benefits
Package, as more fully described in Exhibit A attached hereto.

         4. Vacation: Fringe Benefits: Reimbursement of Expenses.
In addition to normal business holidays, the Executive shall be entitled to two
(2) weeks annually of fully paid vacation during the initial and each extended
term of this Agreement. He shall not be entitled to receive monetary or other
valuable consideration for vacation time to which he is entitled but does not
take. The timing of vacation periods shall be within the discretion of the
Company, reasonably exercised so as not to unnecessarily inconvenience the
Executive.

During his period of employment hereunder, the Executive shall further be
entitled to (a) such leave by reason of physical or mental disability or
incapacity and to such participation in medical and life insurance, pension
benefits, disability and other fringe benefit plan as the Company may make
generally available to all of its executive employees from time to time:
subject, however, as to such plans, to such budgetary constraints or other
limitations as many be imposed by the Board of Directors/Managers of the Company
from time to time; and (b)reimbursement for all normal and reasonable expenses
necessarily incurred by him in the performance of his obligations hereunder,
subject to such reasonable substantiation requirements as may be imposed by the
Company.

                                       2

         5. Proprietary Interests.
During or after the expiration of his term of employment with the Company, the
Executive shall not communicate or divulge to, or use for the benefit of. any
individual, association, partnership, trust, corporation or other entity except
the Company, any proprietary information of the Company received by the
Executive by virtue of such employment, without first being in receipt of the
Company's written consent to do so. Executives employment shall be subject to
the stipulations and conditions outlined in Exhibit C, attached hereto.

         6. Restrictive Covenant.
During the term of his employment hereunder and for the two (2) year period
following the termination thereof for any reason other than (a) the Company's
discontinuance of activities; (b) an adjudication of the Company's material
breach of any of its obligations set forth in Sections 1-4, inclusive; or (c) a
termination of the Executive by the Company under the provisions of subparagraph
(d) (2) of Section 8. below, the Executive shall not, directly or indirectly,
engage in or become an owner of, render any service to, enter the employment of,
or represent or solicit for any business which competes with any activity of the
Company conducted at any time during the Executive's period of employment and
which is located in any county of the State of Missouri in which the Company
shall maintain any activity. This covenant specifically excludes the clinical
practice of medicine (general internal medicine and nephrology). The parties
expressly agree that the duration and geographical area of this restrictive
covenant are reasonable.

This covenant shall be construed as an agreement independent of any other
provision herein, and the existence of any claim or cause of action of the
Executive against the Company regardless of how arising, shall not constitute a
defense to the enforcement by the Company of its terms. If any portion of the
covenant is held by a court of law to be unenforceable with respect either to
its duration or geographical area, for whatever reason, it shall be considered
divisible both as to time and geographical area, so that each month of a
specified period shall be deemed a separate period of time and each county
within the State of Missouri a separate geographical area, resulting In an
intended requirement that the longest lesser period of time or largest lesser
geographical area found by such court to be a reasonable restriction shall
remain an effective restrictive covenant, specifically enforceable against the
Executive.

Notwithstanding any statement contained in this Section 6. to the contrary.
Legal or beneficial ownership by the Executive of a less than 'five percent (5%)
interest in a competitive corporation at least one {1) class of capital stock of
which is publicly traded on a national or regional stock exchange Dr by means of
an electronic interdealer quotation system, shall not be deemed to constitute a
breach by the Executive of the terms hereof.

                                       3

         7. Remedies for Breach of Executive's Obligations.
The parties agree that the services of the Executive are of a personal,
specific, unique and extraordinary character and cannot be readily replaced by
the Company. They further agree that in the course of performing his services,
the Executive will have access to v8nous types of proprietary information of the
Company, which, if released to others or used by the Executive other than for
the benefit of the Company. In either case without the Company's consent, could
cause the Company to suffer irreparable injury. Therefore, the obligations of
the Executive established underss.ss.5. and 6. hereof shall be enforceable both
at law and in equity, by injunction, specific performance, damages or other
remedy; and the right of the Company to obtain any such remedy shall be
cumulative and not alternative and shall not be exhausted by anyone or more uses
thereof.

         8. Modification and Termination.
a. Modification. This Agreement may be amended or n1odified only with the mutual
   written consent of the parties, and in its present form consists of the
   entire Agreement between the parties.

b. Termination - General. This Agreement is subject to termination prior to
   the expiration of its initial or any extended term, if by the Executive upon
   delivery to the Company of written notice of such intention, which notice
   shall be deemed to result in termination thirty (30) days after its receipt
   by the Company (the Company having the right following such receipt to
   accelerate the effective date of termination but retaining the obligation to
   pay Executive his compensation due for the full thirty (30) day period) and
   if the Company upon the occurrence of any one of the following events: (a)
   the death of the Executive; (b) the occurrence to Executive of a physical or
   mental disability which, in the judgment, reasonably exercised, of the Board
   of Directors/Managers, renders him unable to perform his normal duties on
   behalf of the Company for a continuous period of six (8) months (measured
   from the first day of the month immediately following the occurrence of such
   disability); or (c) a determination by the Board of Directors/Managers that
   there is cause (as described in subsection d. below) to terminate Executive's
   employment. If the Company discontinues all Company activities during the
   first six (6) months of this Agreement, the Executive shall be paid ninety
   (90) days of his compensation.

c. By Death or Disability. In the event of the Executive's death, his base
   compensation otherwise due for the succeeding three (3) full calendar months
   following his death shall be paid to his Beneficiary. In the event of his
   disability, for the period ending on the last business day of the third
   calendar month following the occurrence of such disability, the Executive
   shall be paid his base compensation (reduced by any amount received by the
   Executive under the terms of any disability insurance policy maintained by
   the Company at its sole expense); thereafter, for the succeeding three (3)
   months shall be treated as being on an authorized but unpaid leave of
   absence.

                                       4

d. For Cause. In the event of a decision by the Board of Directors/Managers
   to terminate Executive's employment for cause:
        1. If, In the judgment of the Company's Board of Directors/Managers,
           reasonably exercised, such termination is due to (i) the Executive's
           willful misconduct or gross negligence: (ii) his conscious disregard
           of his obligations hereunder or of any other duties reasonably
           assigned him by the Company; (iii) his repeated conscious violation
           of any provision of the Company's By-Laws or of its other stated
           policies, standards or regulations; (iv) his commission of any act
           involving moral turpitude; or (v) a determination that he has
           demonstrated a dependence upon any addictive substance, including
           alcohol, controlled substances, narcotics or barbiturates; then, upon
           1ermination, he shall be entitled to receive severance pay in an
           amount equal to ten percent (101:/0) of his annual base compensation.
           As a condition precedent to the Company's right to terminate this
           Agreement for one of the causes specified in the preceding sentence
           which requires a repeated action or omission by the Executive
           clauses (i), (ii) and (iii), there shall have been created by the
           Company and furnished to the Executive, within the sixty (60) day
           period immediately following commission of the proscribed act or
           omission, a written description thereof and a statement advising him
           that the Company views such conduct as being of the type which could
           lead to a termination of this Agreement under the provisions of
           Section 8d.  Further, if the company seeks to terminate this
           Agreement on the basis of clause (iii), it must be able to
           demonstrate that the Executive has been furnished with a copy of the
           By-Law provision, or of the policy, standard or regulation, which he
           is being accused of having violated, at a time prior to the alleged
           commission of the violation.

        2. If certain performances are not met during this Agreement, those
           being fifty percent (50%) of the performance requirements in Exhibit
           A, the Agreement may be terminated, and Executive shall be entitled
           to receive an amount equal to twenty-five percent (25%) of his annual
           base compensation.

e. Payment of Termination Compensation; Continued Effectiveness of Certain
Obligations. Any compensation due the Executive as a result of the premature
termination of his employment status shall be paid to him after termination as
one lump sum. No termination or expiration of this Agreement, whether
consummated by action of either party or by operation of the terms hereof, shall
relieve the Executive from his continued performance of the obligations
established under Sections 5. and 6. hereof.

                                       5

        9. Indebtedness of Executive. 
If, during the course of his employment, Executive becomes Indebted to the
Company for any reason, the Company shall, if it so elects, have the right 10
set-off and to collect any sums due it from the Executive out of any amounts
which it may owe to the Executive for unpaid compensation. In the event that
this Agreement terminates for any reason, all sums owed by the Executive to the
Company shall become immediately due and payable.

        10. Miscellaneous Provisions.
a. Nonassignability: Neither this Agreement nor any right or interest hereunder
shall be assignable by the Executive, his Beneficiary of his legal
representatives except as otherwise expressly provided herein.

b. Enforceability: If any term or condition or this Agreement shall be invalid
or unenforceable to any extent or in any application, then the remainder of this
Agreement, and such term or condition except to such extent or in such
application, shall not be affected thereby and each and every term and condition
of this Agreement shall be valid and enforced to the fullest extent and in the
broadest application permitted by law.

c. Notice: All notices or other communication are required or permitted to be
furnished pursuant to this Agreement shall be in writing and shall be considered
as properly furnished if hand delivered, mailed from within the United
States by certified or registered mail, or sent by prepaid telegram to the
recipient party at the address appearing in the preamble to this Agreement or to
such other address as any such party may have designated by like notice
forwarded to the other party hereto. Change of address notices shall be deemed
furnished when received. Ail other notices shall be deemed furnished when
mailed, telegraphed or hand delivered.

d. Application of Missouri Law: This Agreement, and the application or
interpretation thereof, shall be governed exclusively by its terms and by the
laws of the State of Missouri. Venue shall be deemed located in St. Louis
County. Missouri.

e. Counterparts: This Agreement may be executed by any number of counterparts,
each of which shall be deemed an original, but all of which together shall
constitute one and the same instrument.

f. Binding Effect: Each of the provisions and agreements herein contained shall
be binding upon and ensure to the benefit of the personal representatives,
devisees. heirs, successors, transferees and assigns of the respective parties
hereto.

                                       6

g. Beneficiary: As used herein, the term "Beneficiary" shall mean the person or
persons (who may be designated contingently or successively and who may be an
entity other than an individual, including an estate or trust) designated on a
written form prescribed by the Board of Directors/Managers to receive the
expiration of Agreement or death benefits described in Section 8. above. Each
Beneficiary designation shall be effective only when filed with the Secretary of
the Company during the Executive's lifetime. Each Beneficiary designation filed
with the Secretary will cancel all designations previously so filed.

If the Executive fails to properly designate a Beneficiary or if the Beneficiary
predeceases the Executive or dies before complete distribution of the benefit
has been made, the Company shall distribute the benefit (or balance thereof) to
the surviving spouse of the Executive or if he be then deceased to the
Executive's estate.

h. Legal Fees and Costs: If a legal action is initiated by any party to this
Agreement against another, arising out of or relating to the alleged performance
or non-performance of any right or obligation established hereunder, or any
dispute concerning the same, any and ail fees, costs and expenses reasonably
incurred by each successful party or him or its legal counsel in investigating,
preparing for, prosecuting, defending against, or providing evidence, producing
documents or taking any other action in respect of, such action shall be the
joint and several obligation of and shall be paid or reimbursed by the
unsuccessful party.

IN WITNESS WHEREOF, the parties have hereunto executed this Agreement.
David Moskowitz Monopath, LLC

   David Moskowitz                             Monopath, LLC

By:/s/David Moskowitz                          By:/s/David Moskowitz
   David Moskowitz, Personally                 David Moskowitz-Managing Director

Attest:

Witnesses

Sign /s/Carl Smith, III                        Name /s/R. Craig Hall

Print Carl Smith, III                          Print R. Craig HallEx. 10.11

Exhibit 10.11  Option Agreement with David Moskowitz

                                 GENOMED, INC.
                             STOCK OPTION AGREEMENT

     THIS STOCK OPTION AGREEMENT is made this 18th day of March, 2002, by and
between GenoMed, Inc (the "Company") and David Moskowitz ("You" and "Your").

                                    RECITALS

     WHEREAS, the Company has entered into this Agreement for the purpose of
securing for the Company the benefits of the incentive inherent in common stock
ownership by a key employee of the Company who is largely responsible for the
Company's future growth, and continued financial success, and of affording You
the opportunity to obtain or increase a proprietary interest in the Company and,
thereby, to have an opportunity to share in the success of the Company.

     WHEREAS, the granted option shall be a non-qualified stock option which
does not satisfy the requirements of Section 422 of the Internal Revenue Code of
1986, as amended.

     NOW, THEREFORE, it is hereby agreed as follows:

     1. Definitions, When used in this Agreement, the following terms shall have
the following meanings:

     (a) "Agreement" shall mean this Stock Option Agreement.

     (b) "Common Stock" shall mean the common stock of the Company, $0.01 par
value per share.

     (c) "Exercise Amount" shall mean the product of the Option Price and the
number of shares of Common Stock purchased through the exercise of all or part
of the Options granted herein.

     (d) "Exercise Date" shall mean: (a) with respect to the Timed Shares, May
6, 2002 for Twelve Million, Five Hundred thousand (12,500,000) shares and
November 6, 2002 with respect to an additional Twenty-Five Million (25,000,000)
shares as further set forth in Section 4; and (b) with respect to the
Performance Shares, the date of a Triggering Event, as defined in Section 4.

     (e) "Expiration Date" is defined for the Timed Option and the Performance
Option in Section 3.

     (f) "Fair Market Value" of a share of Common Stock shall mean (i) if the
shares of Common Stock are publicly traded, "fair market value" shall mean (A)
the average (on that date) of the high and low prices of the Common Stock on the
principal national securities exchange on which the stock is traded, or (B) the
late reported sale price (on that date) of the Common Stock on the NASDAQ
national market, if the Common Stock is not then traded on a national securities
exchange; or (C) the closing bid price (or average of bid price) last quoted (on
that date) by an established quotation service for over-the-counter securities,
if the Common Stock is not reported on the NASDAQ national market, or (ii) if
the Common Stock is not publicly traded, then "fair market value" shall be the
fair value of the Common Stock as determined by the Company after taking into
consideration all factors which it deems appropriate, including, without
limitation, recent sale and offer prices of the Common Stock in private
transactions negotiated at arm's length.

     (g) "Option" shall mean collectively or alternatively, the Time Option and
the Performance Option.

     (h) "Option Price" shall mean twenty percent (20%) of the Fair Market Value
of a share of the Common Stock of the Company as of the date of issuance of such
Common Stock.

     (i) "Option Shares" shall mean collectively or alternatively, the Time
Shares and the Performance Shares.

     (j) "Purchase Agreement" shall mean a stock purchase agreement in
substantially the form of Exhibit A to this Agreement.

     (k) "Shareholder" shall mean a record owner of the Common Stock.

2.   Grant of Option. Subject to the terms and conditions set forth in this
Agreement, (1) the Company hereby grants You the option to purchase up to
Thirty-Seven Million, Five Hundred Thousand (37,500,000) shares ("Timed
Shares") of the Company's Common Stock at a price equal to the Exercise Amount
("Timed Option"); and (2) upon the occurrence of a Triggering Event (as defined
herein) by November 6, 2006, the Company shall grant You and You will receive
without any further action required by the Company o r You the option to
purchase up to One Hundred Million (100,000,000) shares of the Company's Common
Stock ("Performance Shares"), with the actual number of Performance Shares
subject to the Performance Option dependent upon the Company reaching certain
performance levels ("Performance Option").

3.   Terms of Option. In no event shall any Option be exercisable at any time
after its Expiration Date set forth below. Subject to the terms and conditions
provided in this Agreement, You may purchase all or any portion of such shares
during the period between an Option's Grant Date and Expiration Date. The
"Expiration Date" for each Option is as follows:

     (a) The times Option to purchase Timed Shares shall expire as to Twelve
Million, Five Hundred Thousand (12,500,000) shares of the Timed Shares ten (10)
years after May 6, 2002 and the Timed Option to purchase the remaining
Twenty-Five Million (25,000,000) of the Timed Shares shall expire ten (10) years
after November 6, 2002.

     (b) The Performance Option shall expire ten (10) years after the occurrence
of the chosen Triggering Event.

4.   Exercise of Option.

     (a) Timed Option. Subject to the terms and conditions set forth herein,
until the applicable Expiration Date You may exercise the Timed Option to
purchase: (1) up to Twelve Million, Five Hundred thousand (12,500,000) Timed
Shares on or after May 6, 2002; and (2) the remaining Twenty-Five Million
(25,000,000) Total Timed Shares on or after November 6, 2002.

     (b) Performance Option.

         (i) Upon receiving the Performance Option, You may exercise it in part
or in whole. You must elect one (1) triggering Event sent forth below before
exercising the Performance Option and that selected Triggering Event will be the
only Triggering Event that is used to determine the number of Performance Shares
subject to the Performance Option. Any two (2) or more of the Triggering Events
cannot be combined to determine the number of Performance Shares subject to the
Performance Option. Once You have elected to receive the Performance Option
under a particular Triggering Event, such election shall be irrevocable, and
Performance Shares issued hereunder may be issued only under that Performance
Option. If no Triggering Event has occurred by November 9, 2006, the Company
shall not be obligated to grant the Performance Option hereunder. The Triggering
Events that You may choose from are as follows:

             a. The Company must achieve gross profits as follows: ("Gross
Profit Triggering Event". You may receive an option to purchase One (1) share of
Common Stock for every One Center (.01) worth of gross profit produced by the
Company, up to a maximum of One Hundred Million (100,000,000) shares of Common
Stock, upon the occurrence of this Gross Profit Triggering Event; or

             b. The Company becomes listed and quoted company with either the
NASDAQ Small Cap or the NASDAQ National Market Systems Exchange ("Exchange
Triggering Event"). You may receive an option to purchase up to One Hundred
Million (100,000,000) shares of Common Stock upon the occurrence of this
Exchange triggering Event; or

             c. The Company is purchased or acquired by a larger biotech firm
for a minimum of One Hundred Million Dollars ($100,000,000) is value, i.e., cash
and stock ("Sale Triggering Event"). You may receive an option to purchase up to
One Hundred Million (100,000,000) shares of Common Stock upon the occurrence of
this Sale Triggering Event; or

             d. The valuation of Company by a mutually acceptable independent
firm meets or exceeds the dollar levels outlined below ("Valuation Triggering
Event"). The Company may be appraised from time to time, not more than five (5)
times during the term of the Performance Option by such a firm. Upon the
occurrence of this Valuation Triggering Event, You may receive an option to
purchase up to the number of shares of Common Stock corresponding with the
Company Valuation. The number of shares of Common Stock listed below in the
column designated "Option to Purchase Common Stock," is the aggregated mount of
Common Stock for which You may receive a Performance Option to purchase during
the entire term of the Performance Option for that particular valuation of the
Company. At no time under this Valuation Triggering Event, even after multiple
valuations of the Company, are You entitled to receive a Performance Option for
more than One Hundred Million (100,000,000) shares of Common Stock.

                       Company                  Option to Purchase
                      Valuation                   Common Stock

                     $10,000,000                   10,000,000
                     $20,000,000                   20,000,000
                     $30,000,000                   30,000,000
                     $40,000,000                   40,000,000
                     $50,000,000                   50,000,000
                     $60,000,000                   60,000,000
                     $70,000,000                   70,000,000
                     $80,000,000                   80,000,000
                     $90,000,000                   90,000,000
                    $100,000,000                  100,000,000

         (ii) The Company shall notify You promptly in writing of the occurrence
of any Triggering Event, it being understood that the giving of such notice by
the Company shall not be condition to Your right to receive the Performance
Option.

5.   Survivability of Right to Exercise Option.

     (a) If you terminate employment with the Company for any reason You
continue to have all rights and obligations granted to You under this Agreement
and You may exercise Your Options to the extent provided herein as if You were
still then employed by the Company, but You may not exercise the Options after
their respective Expiration Dates.

     (b) If You die, Your Options may be exercised, by a legatee or legates
under Your last will, or by Your personal representatives or distributes, at any
time after the Options Grant Date to the extent provided herein, but You may not
exercise the Options after their respective Expiration Dates.

6.   Representations and Warranties of the Company. The Company represents and
warrants to You that:

     (a) The Company is a corporation duly organized, validly existing and in
good standing under the law of the State of Florida and has the corporate power
and authority to enter into this Agreement, and subject to any regulatory
approvals referred to herein to consummate the transactions contemplated hereby.

     (b) The execution and delivery of this Agreement by the Company and the
consummation by the Company of the transactions contemplated hereby have been
duly authorized by all necessary corporate action on the part of the Company and
no other corporate proceedings on the part of the Company are necessary to
authorize this Agreement or any of the transactions with its terms.

     (c) This Agreement has been duly executed and delivered by the Company,
constitutes a valid and binding obligation of the Company and, assuming this
Agreement constitutes a valid and binding obligation to You, is enforceable
against the Company in accordance with its terms.

     (d) The Company has taken all necessary corporate action to authorize and
reserve for issuance and to permit it to issue, upon exercise of an Option, and
at all times from the date hereof through the expiration of the Options will
have reserved, authorized and unissued shares of the Company Common Stock equal
to the number of outstanding Option Shares as adjusted pursuant to Section 8
hereof, all of which, upon their issuance and delivery in accordance with the
terms of this Agreement, will be validly issued, fully paid and nonassessable.

     (e) Upon delivery of Option Shares to You upon the exercise of an Option,
You will acquire the Option Shares free and clear of all claims, liens, charges,
encumbrances and security interest of any nature whatsoever.

     (f) The execution and delivery of this Agreement by the Company does not,
and the consummation by the Company of the transactions contemplated hereby will
not, violate, conflict with, or result in a breach of any provision of, or
constitute a default (with or without notice or lapse of time, or both) under,
or result in the termination of, or accelerate the performance required by, or
result in a right of termination, cancellation, or acceleration of any
obligation or the loss of a material benefit under or the creation of a lien,
pledge, security interest or other encumbrance on assets (and such conflict,
violation, default, right of termination, cancellation or acceleration, loss or
creation, a "Violation") of the Company or any of its subsidiaries, which
Violation would have a material adverse effect on the Company or You.

7.   Option Nontransferable. The Option shall be neither transferable nor
assignable by You other than you will or by the laws of descent and
distribution, and my be exercised, during Your lifetime, only by You.

8.   Adjustment in Option Shares.

     (a) In the event any change is made to the Common Stock of the Company
issuable under this Agreement by reason of any stock split, stock dividend,
combination of shares, or other changes affecting the outstanding Common Stock
as a class without receipt of consideration then appropriate adjustments will be
made to (i) the total number of Option Shares subject to unexercised Options and
(ii) the Option Price, in order to reflect such change and thereby precluded a
dilution or enlargement of benefits hereunder.

     (b) If the Company is the surviving entity in any merger or other business
combination, then the number of Option Shares subject to unexercised Options, if
outstanding under this Agreement immediately after such merger or other business
combination, shall be appropriately adjusted to apply and pertain to the number
and class of securities which would be issuable to You in the consummation of
such merger or business combination if the Option were exercised immediately
prior to such merger or business combination, and appropriate adjustments shall
be made to the Option Price, provided the aggregate Option Price payable
hereunder shall remain the same.

     (c) If the Company is not the surviving entity in a  merger or other
business combination, then as to the balance of the Option Shares not yet
purchased by You, You shall have the right to receive on the effective date of
the merger the difference in cash between the Option Price of said shares and
the Fair Market value of the consideration per share of Common Stock of the
Company paid as a result of the merger or combination whether or not You had the
right to acquire such shares under Section 2 above.

9.   Privilege of Stock Ownership.  You shall not have any of the rights of a
Shareholder with respect to the Option Shares until You have exercised the
Option and paid the Exercise Amount.

10.  Manner of Exercising Option.

     (a) In order to exercise an Option with respect to all or any part of the
Option Shares for which Option is at the time exercisable, You (or in the case
of exercise after death, Your executor, administrator, heir or legatee, as the
case my be) must take the following actions.

         (i) execute and deliver to the Secretary of the Company a Purchase
Agreement.

         (ii) pay the Exercise Amount for the purchased shares in one or more of
the following alternative forms.

             (A) full payment, in cash or cash equivalents; or

             (B) full payment in shares of Common Stock of the Company, by
delivering shares that You already own for at least six months having a Fair
Market Value equal to the Exercise Amount; or

             (C) the direction to Company to withhold from the number of shares
of Common Stock otherwise issuable upon exercise of the Option that number of
shares of Common Stock having an aggregate fair market value on the date of
exercise equal to the Aggregate Exercise Amount of all shares of Common Stock
subject to such exercise; or

             (D) by the combination of 7(a)(iii)(A) and 7(a)(iii)(B) or
7(a)(iii)(C) above, equal in aggregate to the full Exercise Amount; or

             (E) any other form which the Company may in its discretion approve
at the time of exercise of this option; and

         (iii) furnish to the Company appropriate documentation that the person
or person exercising the option, if other than You, have the right to exercise
this option;

         (iv) in the case of the exercise of the initial exercise of the
Performance Option, indicate which Triggering Event You have selected pursuant
to Section 4.

     (b) Options shall be deemed to have been exercised with respect to the
number of Option Shares specified in the Purchase Agreement at such time as the
executed Purchase Agreement for such shares and payment of the Exercise Amount
shall have been delivered to the Company. Payment of the Exercise Amount shall
immediately become due and shall accompany the Purchase Agreement. The Fair
Market Value of shares tendered in payment of the Exercise Amount shall be
determined as of such date. As soon thereafter as practical, the Company shall
mail or deliver to You or to the other person or persons exercising the Option a
certificate or certificates representing the shares so purchased and paid for.

11.  Compliance with Laws and Regulations

     (a) The exercise of these Options and the issuance of Option Shares upon
such exercise shall be subject to compliance by the Company and You with all
applicable requirements of law resisting thereto.

     (b) In connection with the exercise of these Options, You shall execute and
deliver to the Company such representations in writing as may be requested by
the Company in order for it to comply with the applicable requirements of
federal and state securities laws.

12.  Successors and Assigns. The provisions of this Agreement shall inure to the
benefit of, and be binding, upon, Your successors, administrators, heirs, legal
representatives and the successors and assigns of the Company.

13.  No Employment or Service Contract. Except to the extent the terms of any
employment or service contract between the Company and You expressly provide
otherwise, no provision of this Agreement shall be construed so as to grant You
any right to remain as an employee of the Company or its parent or subsidiary
corporations, if any, for any period of specific duration.

14.  Notices. Any and all notices referred to or relating to this Agreement
shall be furnished in writing and delivered in person or sent by registered mail
to You. A copy of all notices shall be sent to the Company at its principal
place of business.

15.  Withholding. If You acquire option Shares, the Company shall not deliver or
otherwise make such shares available to You until You pay to the Company to cash
(or any other form acceptable to the Company) the amount necessary to enable the
Company to remit to the appropriate government entity or entities on Your behalf
the amount required to be withheld for Your wages with respect to such
transaction.

16.  Construction. This Agreement and the option evidenced hereby are in all
respects limited by the subject to the express terms and provisions of this
Agreement. All decisions of the Company with respect to any question or issue
arising under this Agreement shall be conclusive and binding on all persons
having an interest in this option.

17.  Governing Law. The interpretation, performance, and enforcement of this
Agreement shall be governed by the laws of the State of Missouri.

                  [Remainder of page intentionally left blank]

     IN WITNESS WHEREOF, the Company has caused this Agreement to be executed on
its behalf by its duly authorized officer, and You also have executed this
Agreement, all as of the day and year indicated above.

                                                GENOMED, INC

                                                By:/s/Jerry E. White
                                                Title: President and CEO

                                                You:/s/David Moskowitz
                                                Name: David Moskowitz

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