Document:

exv10w1

 

Exhibit 10.1

SEVERANCE AGREEMENT AND RELEASE OF CLAIMS

     This Severance Agreement and Release of Claims (“Agreement”) is made as of the day below
written by and between Daniel E. O’Brien (“DOBRIEN”) and TRM CORPORATION (“TRM”), a publicly-traded
company with headquarters in Portland, Oregon. DOBRIEN and TRM shall be collectively referred to
herein as the “Parties.”

     WHEREAS, DOBRIEN was employed by TRM as its Chief Financial Officer;

     WHEREAS, DOBRIEN’s position is to be terminated effective August 31, 2007 (“Termination
Date"); and

     WHEREAS, the Parties desire to resolve all issues between them, amicably conclude their
relationship, and identify certain continuing obligations of the Parties.

     NOW, THEREFORE, in consideration of the mutual promises, agreements and representations
contained herein, and intending to be legally bound hereby, the Parties agree as follows:

     1. Definitions. As used in this Agreement, any reference to DOBRIEN shall include
himself and, in their capacities as such, his attorneys, heirs, administrators, representatives,
executors, legatees, successors, agents and assigns. Any reference to TRM shall include itself,
its predecessors, successors, controlling or related entities, affiliates, divisions, subsidiaries,
employee benefit plans, managing agents, and joint ventures, and, in their capacities as such, all
of its past, present and future representatives, agents, assigns, attorneys, directors, officers,
partners, shareholders and employees (except DOBRIEN). The term “Person” shall mean a natural
person, corporation, partnership, trust, estate, joint venture, sole proprietorship, government
(and any branch or subdivision thereof), governmental agency, association, cooperative or other
entity. The term “Effective Date” shall mean the eighth (8th) day after DOBRIEN
executes this Agreement and does not revoke it.

     2. TRM’s Obligations. In consideration for this Agreement, in exchange for the
release set forth in paragraph 5 below, and subject to DOBRIEN’s performance of all terms of this
Agreement, TRM agrees that:

          (a) TRM shall pay, DOBRIEN the sums of (i) $170,000 as a severance payment, (ii) $20,000 as a
previously awarded but unpaid “stay bonus”, and (iii) accrued but unpaid salary from August 1, 2007
through Termination Date. TRM will not contest any claim for unemployment that DOBRIEN files with
the state.

          (b) TRM may engage DOBRIEN for consulting services for a period of six months from his
Termination Date at a rate of $200 per hour pursuant to a separate consulting agreement (the
“Consulting Agreement”). DOBRIEN shall be allowed to retain the laptop computer provided by TRM,
but agrees that, at the end of the six month consulting agreement he

 

 

shall destroy all TRM information on the laptop in accordance with paragraph 4(c) herein.
Should TRM require DOBRIEN’s consulting services for any reason, including litigation, after the
consulting term has expired, it shall compensate DOBRIEN at the rate of $200 per hour plus
expenses. DOBRIEN agrees to make himself available as reasonably as may be required to provide
services as requested by TRM.

          (c) TRM will take all such corporate action as is necessary to cause the vesting of all
unvested restricted stock or stock options awarded to DOBRIEN on or before August 31, 2007. TRM
shall additionally take necessary corporate action to extend the expiration date of all stock
options to five years from the Termination Date. DOBRIEN acknowledges that, as a result of such
extension, any incentive stock options held by him will no longer be treated as incentive stock
options under the Internal Revenue Code of 1986, as amended, but rather as non-incentive stock
options.

          (d) Provided that DOBRIEN makes an election to continue health insurance coverage in
accordance with the requirements of COBRA, and subject to the terms and conditions of TRM’s group
health insurance plan, TRM shall pay the employer’s share and the employee’s share of DOBRIEN’s
health insurance premium for family coverage for one year from the Termination Date. DOBRIEN’s
participation in TRM’s healthcare plan shall be otherwise subject to provisions of COBRA.

          (e) TRM shall pay the fee for one year of outplacement services at Lee Hecht Harrison or such
other firm as is mutually agreeable, provided that such fee shall not exceed Fourteen Thousand
Dollars ($14,000).

     3. Consideration Sufficient for Agreement. DOBRIEN acknowledges that the payments and
other consideration provided pursuant to paragraph 2 are in lieu of any other amount or benefit
that would otherwise be due to him from TRM upon separation. DOBRIEN has received separate payment
for any accrued but unused vacation pay.

     4. DOBRIEN’s Obligations. In consideration of this Agreement, and in addition to the
release set forth in paragraph 5 below, and his other covenants herein, DOBRIEN agrees that he:

          (a) Shall not, except with TRM’s express prior written consent, directly or
indirectly, for his own benefit or the benefit of any Person, communicate, disclose, divulge,
publish or otherwise express to any Person, or use for his own benefit or the benefit of any other
Person, any trade secrets, confidential or proprietary knowledge or information, no matter when or
how acquired, concerning the conduct and details of TRM’s business, including without limitation
names of customers and suppliers, marketing methods, trade secrets, policies, prospects and
financial condition;

          (b) Shall immediately resign from all positions held by him, if any, as an officer or director
of TRM and its subsidiaries and affiliates, and from all positions held by him, if any, as a
fiduciary with respect to any employee benefit plan of TRM or its subsidiaries and affiliates.
DOBRIEN, waives, relinquishes and abandons any and all employment with TRM (or its

 

 

parent companies, subsidiaries, sister corporations, partners, related entities, contractors or
sub-contractors) now and forevermore;

          (c) Shall immediately return to TRM, to the extent he has not already done so, all
correspondence, files, customer and prospect lists, notes, computer data, technical data and other
documents and materials that contain any such confidential or proprietary knowledge or information,
without retaining any copies of such materials for himself;

          (d) Shall, except as provided in paragraph 2(b), return all other property belonging to TRM,
including, but not limited to, all business machines, computers, computer hardware and software
programs, telephones (cellular, mobile or other), pagers, keys, card keys and credit cards;

          (e) Shall fully cooperate with TRM as needed in the future with respect to any legal matters
involving TRM or any of its subsidiaries and affiliates, provided that TRM will use good faith
efforts to give DOBRIEN reasonable advance notice of the need for such cooperation, and TRM shall
reimburse DOBRIEN’s reasonable costs, including attorney fees, in connection with any lawsuit(s) or
investigation(s) in which DOBRIEN may be named as a defendant in his capacity as an officer of TRM;
and

          (f) Shall confirm that Section 3 of the Employment Agreement, dated August 12, 2005 between
DOBRIEN and TRM (the “Former Employment Agreement”) shall remain in full force and effect and agree
to continue to be bound by Section 3 of the Former Employment Agreement, except to the extent that
such provision is directly contradicted by a provision contained herein.

     5. Release of Claims. DOBRIEN hereby irrevocably and unconditionally releases and
forever discharges TRM and each and all of its parents, subsidiaries, sister corporations,
partners, officers, agents, directors, shareholders, supervisors, employees, representatives,
attorneys, insurers, and their successors and assigns and all persons acting by, through, under, or
in concert with any of them from any and all charges, grievances, complaints, claims, and
liabilities of any kind or nature whatsoever, known or unknown, suspected or unsuspected
(hereinafter referred to as “claim” or “claims”) which DOBRIEN at any time heretofore had or
claimed to have or which DOBRIEN may have or claim to have regarding events that have occurred as
of the effective date of this Agreement, including, but not limited to, any and all claims related
or in any manner incidental to DOBRIEN’s employment, the termination of his employment at TRM, or
stock options. All claims (including related attorney fees and costs) are forever barred by this
Agreement and without regard to whether those claims are based on any alleged breach of a duty
arising in contract or tort, by statute or regulation; any alleged unlawful act, including, but not
limited to, unpaid wages, benefits or other compensation or penalty, liquidated damages, employment
discrimination, workers compensation benefits, personal injuries of any nature, defamation, any
other claim or cause of action; and regardless of the forum in which it might be brought. The
claims which DOBRIEN forever releases and discharges by this Agreement include, but are not in any
way limited to all claims under the described statutes: ORS 652.140 et seq., the Fair Labor
Standards Act, 29 U.S.C. Sections 200 et seq., ORS Chapter 652 et seq., ORS Chapter 653 et seq.,
ORS Chapter 654 et seq., ORS Chapter 655 et seq., ORS Chapter 659 et seq., ORS 659A et. seq.,
Discrimination in Employment in violation of Title VII of the Civil Rights Act of 1964, as amended,
42 U.S.C.

 

 

Sections 2000-e et seq., the Americans With Disabilities Act, 42 U.S.C. Sections 12101 et seq., the
Age Discrimination in Employment Act, 29 U.S.C. Sections 621 et. seq., the Equal Pay Act of 1963,
29 U.S.C. Section 206(d), the Fair Labor Standards Act, 29 U.S.C. Sections 200 et seq., the Civil
Rights Act of 1866, 42 U.S.C. Section 1981, the Family and Medical Leave Act, 29 U.S.C. Section
2601 et seq., the Oregon Civil Rights Act, ORS Chapter 659A et seq., the Oregon Family Leave Act,
ORS Chapter 659A.470 et seq., Oregon Statutes Sections 44-1001 et. seq, 44-1111 et. seq.

     The Parties agree that any provision of law which precludes a party from releasing any unknown
or unasserted claims is hereby waived.

     Notwithstanding any other provision of this Agreement, the Parties further agree that this
release is not intended to (i) change DOBRIEN’s status or rights as a participant in any TRM
retirement plan or (ii) limit any of the obligations of the Parties expressly set forth or
acknowledged in this Agreement.

     6. Confidential Nature of Agreement and Employment. The Parties agree that they shall
keep the existence of this Agreement and all of its terms confidential, and they agree not to
disclose or publish same except in response to a subpoena or to their respective attorneys,
accountants and financial advisors, who shall be advised of and bound by this confidentiality
provision upon such disclosure or publication, or as required by regulation. The Parties also
agree not to discuss with anyone, including but not limited to, current, former or prospective TRM
employees, the terms and conditions of DOBRIEN’s employment with TRM, or the termination thereof,
unless otherwise required by law to do so, except that TRM shall have the right to disclose such
information to its management employees with a need to know and to disclose such information as may
be required by applicable securities or other laws.

     7. Non-Disparagement. DOBRIEN agrees that he shall refrain from making any negative,
disparaging or derogatory comments about the TRM, including but not limited to, any public or
private remarks or statements that would injure the business or reputation of TRM, or its officers,
managers, members, directors, partners, agents or employees. TRM agrees that it shall refrain from
making any negative, disparaging or derogatory comments about DOBRIEN, including but not limited
to, any public or private remarks or statements that would injure the business or reputation of
DOBRIEN.

     8. Duty Not to Solicit Employees, Customers/Clients and Suppliers. DOBRIEN further
agrees that for a period of one year after the termination of employment, he shall not for any
reason directly or indirectly, by any means or device whatsoever, for himself or on behalf of, or
in conjunction with any person, partnership or corporation, do any one or more of the following:
(A) induce, entice, hire, or attempt to hire or employ, any person who is, at that time, an
employee of TRM or of its subsidiaries, partners, co-venturers or related entities (a
"Prohibited Employee”) or otherwise call upon any Prohibited Employee for the purpose or
with the intent of enticing such Prohibited Employee away from or out of the employ of TRM or of
its parents, subsidiaries, partners, co-venturers or related entities provided that the DOBRIEN
shall not be precluded from hiring any person (i) who responds to any general solicitation or
advertisement, or (ii) who contacts DOBRIEN on his/ her own initiative without any direct or
indirect solicitation or encouragement from the DOBRIEN, other than any general solicitation or

 

 

advertisement; or (B) for any purpose which is competitive with TRM, call upon any person or entity
which is, at that time, or which has been, within one year prior to that time, a customer or
supplier of TRM or of its parents, subsidiaries, partners, co-venturers or related entities.
Nothing in this Agreement, however, shall bar DOBRIEN from working as an employee or consultant
with an entity that purchases any part of TRM’s business operations.

     9. Covenant Not to Sue. Each Party to this Agreement agrees and covenants not to sue
the other Party with respect to any matter arising before the Effective Date of this Agreement or
covered by the release set forth in paragraph 6 above, and not to assert in any action, suit,
litigation or proceeding any matter arising before the Effective Date of this Agreement or covered
by the release set forth in paragraph 5 above. This covenant extends to, but is not limited to,
proceedings to negate, modify or reform this Agreement; provided, however, that it does not intend
to interfere with either Person’s protected right to file a charge with or participate in an
investigation or proceeding pursuant to the statutes administered by the Equal Employment
Opportunity Commission, including a charge contesting the validity of this Agreement under the Age
Discrimination in Employment Act. In any event, DOBRIEN understands that, by signing this
Agreement, he waives any right he may have to recover money or other relief in any lawsuit or
proceeding he brings or that is brought on his behalf by any agency or third party against TRM
based on events arising through the date he signs this Agreement other than for nonperformance of
this Agreement. Except where otherwise permitted under this paragraph, DOBRIEN agrees that such
action shall be dismissed with prejudice upon the presentation of this Agreement to the Court.
DOBRIEN agrees that he will be responsible for all of TRM’s legal fees and costs incurred in
defending such action if in fact the Court dismisses such action on the basis of this Agreement.
Similarly, TRM agrees that it will be responsible for all of DOBRIEN’s legal fees and costs
incurred in defending any such action brought by TRM if in fact a court dismisses such action on
the basis of this Agreement.

     10. Covenant Not to Compete. DOBRIEN agrees that for a period of one year after the
termination of employment, DOBRIEN shall not, without prior written consent, compete with TRM,
either directly or indirectly, in the geographical area where DOBRIEN has served TRM’s customers,
and shall not perform services for or own an interest in any business that does so.

     11. Non-Admission of Liability. By entering into this Agreement, no Party admits to
any wrongdoing against the other Party. Indeed, the Parties agree that neither this Agreement, nor
the furnishing of the consideration for the release contained herein shall be deemed or construed
at any time for any purpose as an admission by TRM of any liability or unlawful conduct of any
kind. TRM expressly denies that it engaged in any unlawful conduct of any kind.

     12. Injunctive Relief; Payments. If either Party breaches any of the covenants set
forth in this Agreement, the Parties acknowledge that such breaches will result in irreparable
injury to the injured Party for which monetary damages are not adequate and that, in the event of
any such breach, the injured Party shall be entitled, in addition to all other rights and remedies
which such injured Party may have at law or in equity, to have an injunction issued by any
competent court enjoining and restraining the other Party, and all other persons involved therein,
from continuing such breach.

 

 

     13. Governing Law, Jurisdiction and Venue. This Agreement shall be governed by, and
construed in accordance with, the laws of the State of Oregon. Any action arising out of, or
relating to, any of the provisions of this Agreement may, at the election of TRM, be brought and
prosecuted only in the United State District Court for the District of Oregon or the Circuit Court
of the State of Oregon, County of Multnomah, and in the event of such election, the Parties consent
to the jurisdiction and venue of said court.

     14. Severability. If one or more of the provisions contained in this Agreement shall
for any reason be invalid or unenforceable, such provision or provisions may be modified by any
appropriate judicial body so that they are valid and/or enforceable. If any provision is stricken,
the remaining provisions of this Agreement shall remain valid and enforceable.

     15. Entire Agreement. The parties understand that no promise, inducement, or other
agreement not expressly contained herein has been made conferring any benefit upon them; that this
Agreement contains the entire agreement between the Parties; that this Agreement may not be
altered, amended, or modified, in any respect, except by a writing duly executed by both Parties;
and that the terms of this Agreement are contractual and not recitals only. This Agreement shall
be binding upon TRM and DOBRIEN and their successors, heirs and assigns.

     16. DOBRIEN understands and agrees that he:

          (a) Has executed this Agreement only after having had an opportunity to consider it for a full
forty five (45) days.

          (b) Has carefully read and fully understands all of the provisions of this Agreement.

          (c) Is, through this Agreement, releasing TRM, and its agents, servants, employees, parent
companies, subsidiaries, partners, and related entities, from any and all claims he may have
against them or it.

          (d) Knowingly and voluntarily agrees to all of the terms set forth in this Agreement.

          (e) Knowingly and voluntarily intends to be legally bound by this Agreement.

          (f) Was advised and hereby is advised in writing to consider the terms of this Agreement and
consult with an attorney of his choice before signing this Agreement.

          (g) Has a full seven (7) days following his execution of this Agreement to revoke this
Agreement and has been and hereby is advised in writing that this Agreement shall not become
effective or enforceable until the revocation period has expired.

          (h) Understands that he is releasing rights or claims under the Age Discrimination in
Employment Act of 1967 (29 U.S.C. § 621, et seq.

 

 

          (i) Understands that rights or claims under the Age Discrimination in Employment Act of 1967
(29 U.S.C. § 621, et seq.) that may arise after the date this Agreement is executed are not
waived.

     17. Consultation With Counsel, Period to Review. DOBRIEN acknowledges that it has
been his decision alone whether or not to consult with counsel regarding this Agreement. DOBRIEN
acknowledges that he has 45 days in which to consider this Agreement before signing it and that he
was permitted to use as much of that period as he wished prior to signing, but by his signature
below DOBRIEN acknowledges that he has chosen to voluntarily execute this Agreement earlier and to
waive the remaining days of such 45-day period. DOBRIEN acknowledges that no proposal or actual
change that he or his counsel makes with respect to this Agreement will restart the 45-day period.

     18. Revocation Period. DOBRIEN also understands and acknowledges that he may revoke
this Agreement within seven (7) days of signing it. Should he wish to do so, he must submit
written notice of his revocation in writing to Angela C. Childers, Director of Human Resources, TRM
Corporation, 5208 N.E. 122nd Avenue, Portland, OR 97230-1074, no later than 5:00 p.m. on
the 7th day after DOBRIEN has signed this Agreement. If DOBRIEN revokes this Agreement,
it shall not be effective or enforceable, and he must return any of the consideration described in
paragraph 2 above. DOBRIEN also understands that none of TRM’s obligations under this Agreement,
including without limitation the obligations set forth in paragraph 2, shall become due prior to
the Effective Date.

     19. If the approval of this Agreement, or any term thereof, is required by any agency, court
or tribunal in order to make its terms effective and enforceable, the Parties agree that they shall
execute any documents necessary to obtain such approval(s) of this Agreement, and will urge that
this Agreement be approved.

     20. Section Headings. Section headings in this Agreement are for convenience of
reference only and shall neither constitute a part of this Agreement nor affect its interpretation.

     21. EACH PARTY TO THIS AGREEMENT REPRESENTS TO THE OTHER THAT SUCH PARTY HAS READ THE TERMS OF
THIS AGREEMENT; THAT SUCH PARTY HAS HAD AN OPPORTUNITY TO FULLY DISCUSS AND REVIEW THE TERMS OF
THIS AGREEMENT WITH LEGAL COUNSEL; THAT SUCH PARTY UNDERSTANDS THE CONTENTS HEREOF; AND THAT SUCH
PARTY FREELY AND VOLUNTARILY ASSENTS TO ALL THE TERMS AND CONDITIONS HEREOF, AND SIGNS THE SAME AS
THAT PARTY’S OWN FREE ACT, AND WITH THE INTENTION OF RELEASING THE OTHER PARTY FROM EACH AND EVERY
CLAIM RELATING IN ANY WAY TO THE EMPLOYMENT RELATIONSHIP BETWEEN THEM.

 

 

     IN WITNESS WHEREOF, and intending to be legally bound, the Parties agree to the terms of this
Agreement.

Date: September 11, 2007

	 	 	 	 	 
	 	 	 
	 	/s/ Daniel E. O’Brien
 	 
	 	Daniel E. O’Brien 	 
	 	 	 
	 

	 	 	 	 	 
	Date:  September 17, 2007 	TRM Corporation

 	 
	 	By:  	/s/ Richard B. Stern
 	 
	 	Title:  	President and Chief Executive Officerexv4w5

 

POLYMEDIX, INC.

REGISTRATION RIGHTS SUBSTITUTION AGREEMENT

     THIS REGISTRATION RIGHTS SUBSTITUTION AGREEMENT (this “Agreement”) is made this ___day of
___2007 by and among PolyMedix, Inc., a Delaware corporation (the “Company”), and the
undersigned Holders (as defined in Section 1.1(a)) of Registrable Securities (as defined in Section
1.1(b)) and identified on Exhibit A attached hereto and as may be amended and supplemented
from time to time.

SECTION 1

REGISTRATION RIGHTS

     1.1     Certain Definitions. As used in this Section 1:

          (a)     The term “Holder” (collectively, “Holders”) means each Holder holding Registrable
Securities, securities exercisable or convertible into Registrable Securities or securities
exercisable for securities convertible into Registrable Securities.

          (b)     The term “Registrable Securities” means (i) the Company’s common stock, par value $0.001
per share (the “Common Stock”) issued or issuable upon conversion of the shares of the Company’s
Series 1 Convertible Preferred Stock (the “Series 1 Stock”) held by a Holder, (ii) Common Stock
issued or issuable upon exercise of the Company’s warrants issued in connection with the offer and
sale of its Series 1 Stock and held by a Holder, and (iii) any Common Stock issued as (or issuable
upon the conversion or exercise of any warrant, right or other security that is issued as) a
dividend or other distribution with respect to, or in exchange or in replacement of, such
securities; provided, however, that shares of Common Stock or other securities
shall only be treated as Registrable Securities if and so long as (A) they have not been sold to or
through a broker or dealer or underwriter in a public distribution or a public securities
transaction or sold for cash or other property, (B) they have not been sold in a transaction exempt
from the registration and prospectus delivery requirements of the Act under Section 4(1) thereof so
that all transfer restrictions and restrictive legends with respect thereto are removed upon the
consummation of such sale, and (C) the registration rights associated with such securities have not
been terminated pursuant to Section 1.8 hereof.

          (c)     The terms “register,” “registered” and “registration” refer to a registration effected by
filing with the Securities and Exchange Commission (the “SEC”) a registration statement (the
“Registration Statement”) in compliance with the Securities Act of 1933, as amended (the “Act”) and
the declaration or ordering by the SEC of the effectiveness of such Registration Statement.

     1.2     Substitution of Registration Rights. The Company and each Holder agree that the
registration rights provided herein are in complete substitution for any other registration rights
held by such Holder with respect to the registration of the Company’s securities held by such
Holder, including without limitation registration rights pursuant to

 

 

any agreement or instrument between the Holder and the Company, and that any other
registration rights not expressly set forth in this Agreement are hereby terminated.

     1.3     Registration. The Company shall file the Registration Statement covering the
Registrable Securities on the date that is the earlier of (i) ninety (90) days following the
effectiveness of a registration statement filed in connection with an equity financing of the
Company or (ii) September 1, 2007.

     1.4     Expenses of Registration. All expenses incurred in connection with the
registration effected pursuant to Section 1.2, including, without limitation, all registration,
filing and qualification fees (including state securities law fees and expenses), printing
expenses, escrow fees, fees and disbursements of counsel for the Company, fees and disbursements of
one counsel for the participating Holders (to be chosen by the Holders of a majority of the then
outstanding Registrable Securities) up to a maximum of $12,500, and expenses of any special audits
incidental to or required by such registration shall be borne by the Company; provided,
however, that the Company shall not be required to pay stock transfer taxes or
underwriters’ discounts or selling commissions relating to Registrable Securities.

     1.5     Obligations of the Company. Whenever required under this Section 1 to effect the
registration of Registrable Securities pursuant to the Registration Statement, the Company shall:

          (a)     as promptly as practicable, prepare and file with the SEC such amendments and supplements
to the Registration Statement and the prospectus used in connection with such Registration
Statement as may be necessary to keep such Registration Statement effective for the lesser of four
years from the date the Registration Statement is first declared effective by the SEC or until the
Holders have completed the distribution of all Registrable Securities relating to the Registration
Statement, and to comply with the provisions of the Act with respect to the disposition of all
securities covered by the Registration Statement;

          (b)     as promptly as practicable, furnish to the selling Holders such numbers of copies of such
registration statement and each amendment thereto, the prospectus included in such Registration
Statement, (including each preliminary prospectus), in conformity with the requirements of the Act,
and such other documents as they may reasonably request in order to facilitate the disposition of
Registrable Securities owned by them;

          (c)     use its best efforts to register or otherwise qualify the securities covered by such
Registration Statement under such other securities laws of such states and other jurisdictions as
shall be reasonably requested by the Holders or the managing underwriter, provided that the Company
shall not be required in connection therewith or as a condition thereto to qualify to do business;

          (d)     promptly notify each Holder of Registrable Securities covered by such Registration
Statement, at any time when a prospectus relating thereto is required to be delivered under the
Act, of the happening of any event as a result of which the prospectus

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included in such Registration Statement, as then in effect, includes an untrue statement of a
material fact or omits to state a material fact required to be stated therein or necessary to make
the statements therein not misleading in the light of the circumstances then existing;

          (e)     provide a transfer agent and registrar for all such Registrable Securities not later than
the effective date of such Registration Statement;

          (f)     promptly notify the Holders of Registrable Securities of the following events and (if
requested by any such person) confirm such notification in writing: (1) the filing of the
prospectus or any prospectus supplement and the Registration Statement and any amendment or
post-effective amendment thereto and, with respect to the Registration Statement or any
post-effective amendment thereto, the declaration of the effectiveness of such document, (2) any
requests by the SEC for amendments or supplements to the Registration Statement or the prospectus
or for additional information, (3) the issuance or threat of issuance by the SEC of any stop order
suspending the effectiveness of the Registration Statement or the initiation of any proceedings for
that purpose, (4) the commencement or termination of any Blackout Period declared pursuant to
Section 1.5(h), and (5) the receipt by the Company of any notification with respect to the
suspension of the qualification of the Registrable Securities for sale in any jurisdiction or the
initiation or threat of initiation of any proceeding for such purpose; and

          (g)     cooperate with Holders including Registrable Securities in such registration to facilitate
the timely preparation and delivery of certificates representing Registrable Securities to be sold,
such certificates to be in such denominations and registered in such names as such Holders may
request at least two business days prior to any sale of Registrable Securities.

          (h)     at any time during which the Registrable Securities are included in the then-effective
Registration Statement, the Company may suspend the ability of the Holder to sell the Holder’s
Registrable Securities pursuant to the Registration Statement, for a reasonable period or periods
(a “ Black-out Period ”), in the event that (1) an event occurs and is continuing as a result of a
which the Registration Statement including the Registrable Securities, any related prospectus or
any document incorporated therein by reference as then amended or supplement would, in the
Company’s good faith judgment, contain an untrue statement of a material fact or omit to state a
material fact necessary in order to make the statements therein, in the light of the circumstances
under which the were made, not misleading, and (2) the Company determined in its good faith
judgment that the disclosure of such event at such time would be to the detriment of the business,
operations or prospects of the Company or the disclosure otherwise relates to a business
transaction, operations or other material event which has not yet been publicly disclosed.
Notwithstanding the foregoing provisions of this Section 1.5(h), the Company will use reasonable
efforts to limit the aggregate number of days covered by Black-out Periods to no more than twenty
(20) consecutive business days or exceed sixty (60) business days in a particular calendar year.

     1.6     Information by Holder. Each Holder shall timely furnish to the Company all
information and make customary representations and warranties as the

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Company may reasonably request in writing and as shall be required in connection with any
registration, qualification or compliance referred to in this Section 1.

     1.7     Delay of Registration. No Holder shall have any right to obtain or seek an
injunction restraining or otherwise delaying any such registration as the result of any controversy
that might arise with respect to the interpretation or implementation of this Section 1.

     1.8     Termination of Rights. This Agreement and the rights and obligations set forth
herein shall terminate upon the earlier to occur of (1) the written agreement of the Company and
the Holders holding a majority in interest of the Registrable Securities then outstanding or (2)
the earlier of (a) four years from the date the Registration Statement is first declared effective
by the SEC and (b) until the Holders have completed the distribution of all Registrable Securities
relating to the Registration Statement, and to comply with the provisions of the Act with respect
to the disposition of all securities covered by the Registration Statement.

SECTION 2

MISCELLANEOUS

     2.1     Governing Law. This Agreement shall be governed in all respects by the laws of
the State of Delaware without regard to the conflicts of laws principles of any jurisdiction. No
suit, action or proceeding with respect to this Agreement may be brought in any court or before any
similar authority other than in a court of competent jurisdiction in the State of Delaware, and the
parties hereby submits to the exclusive jurisdiction of such courts for the purpose of such suit,
proceeding or judgment. Each of the parties hereto hereby irrevocably waives any right which it
may have had to bring such an action in any other court, domestic or foreign, or before any similar
domestic or foreign authority and agreed not to claim or plead the same.

     2.2     Entire Agreement. This Agreement embodies the entire agreement and understanding
between the parties hereto and supersedes and replaces in their entirety all prior agreements and
understandings relating to the subject matter hereof. This Agreement shall be binding upon and
shall inure to the benefit of the parties hereto and their heirs, executors, legal representatives,
successors and permitted transferees, except as may be expressly provided otherwise herein.
Nothing in this Agreement, express or implied, is intended to confer upon any party, other than the
parties hereto and their successors and assigns, any rights, remedies, obligations or liabilities
under or by reason of this Agreement, except as expressly provided herein.

     2.3     Assignability. Each Holder acknowledges that such Holder may not assign any of
its rights to or interest in or under this Agreement except in connection with a transaction
involving Registrable Securities and in which such securities may be treated as Registrable
Securities pursuant to Section 1.1(b) immediately upon consummating the transaction.

-4-

 

     2.4     Specific Enforcement. The parties hereto expressly acknowledge that they will be
irreparably damaged if this Agreement is not specifically enforced. Upon a breach of the terms,
covenants, or conditions of this Agreement by any party, the Holders and the Company shall, to the
extent not prohibited by law, in addition to all other remedies, each be entitled to seek a
temporary or permanent injunction, without showing any actual damage, and/or a decree for specific
performance, in accordance with the provisions hereof.

     2.5     Amendments. Except as otherwise provided herein, the provisions of this Agreement
may not be amended, modified or supplemented, and waivers or consents to departures from the
provisions hereof may not be given unless consented to in writing by (i) the Company and (ii) the
Holders of at least a majority in interest of the then outstanding Registrable Securities that have
not been sold pursuant to the Registration Statement. Any such written consent shall be binding
upon the Company, and the Holders. No waivers of or exceptions to any term, condition or provision
of this Agreement, in any one or more instances, shall be deemed to be, or construed as, a further
or continuing waiver of any such term, condition or provision.

     2.6     Severability. In the case any one or more of the provisions contained in this
Agreement shall for any reason to be held to be invalid, illegal or unenforceable in any respect,
such invalidity, illegality or unenforceability shall not affect any other provision of this
Agreement and such invalid, illegal and unenforceable provision shall be reformed and construed so
that it will be valid, legal, and enforceable to the maximum extent permitted by law.

     2.7     Notices. Any notice, demand or request required or permitted to be given by
either the Company or a Holder pursuant to the terms of this Agreement shall be in writing and
shall be deemed given when delivered personally or deposited in the United States mail, first class
with postage prepaid, and addressed:

          (a)

	 	 	 
	if to the Company, at:

	 	with a copy to:
	PolyMedix, Inc.

	 	Pepper Hamilton LLP
	170 N. Radnor Chester Road, Suite 300

	 	899 Cassatt Road
	Radnor, PA 19087

	 	400 Berwyn Park
	Attn: Mr. Edward Smith

	 	Berwyn, PA 19312
	Telephone: (484) 598-2332

	 	Attn: Jeffrey P. Libson, Esq.
	Telecopier: (484) 598-2333

	 	Telephone: (610) 640-7837
	Email: esmith@polymedix.com

	 	Telecopier: (610) 640-7835

          (b)     and if to a Holder, to the address of such Holder set forth on Exhibit A to this
Agreement, or such other address as a Holder may request by notifying the other in writing.

     2.8     Delays or Omissions. Any party’s failure to enforce any provision or provisions
of this Agreement shall not in any way be construed as a waiver of any such provision or
provisions, nor prevent that party thereafter from enforcing each and every other provision of this
Agreement. The rights granted all parties herein are cumulative and shall

-5-

 

not constitute a waiver of any party’s right to assert all other legal remedies available to
it under the circumstances.

     2.9     Intent. The Holders agree to execute upon request any further documents or
instruments necessary or desirable to carry out the purposes or intent of this Agreement.

     2.10     Titles and Subtitles. The titles of the sections and subsections of this
Agreement are for convenience of reference only and are not to be considered in construing this
Agreement.

     2.11     Counterparts; Execution by Facsimile. This Agreement may be executed in two or
more counterparts, each of which shall be deemed an original, but all of which together shall
constitute one and the same instrument. This Agreement may be executed by facsimile signature(s)
which shall be binding on the party delivering same, to be followed by delivery of originally
executed signature pages.

*****

-6-

 

     IN WITNESS WHEREOF, the Company has executed this Registration Rights Substitution Agreement
as of the date set forth below.

	 	 	 	 	 
	 	POLYMEDIX, INC. 

 	 
	 	By:  	________________________
 	 
	 	 	Name:  	 	 
	 	 	Title:  	 	 
	 
	 	Date:  	________________________
 	 
	 	 	 
	 	 	 
	 	 	 

 

 

	 	 	 	 	 

POLYMEDIX, INC.

REGISTRATION RIGHTS SUBSTITUTION AGREEMENT

COUNTERPART SIGNATURE PAGE

     IN WITNESS WHEREOF, the undersigned has executed this Registration Rights Substitution
Agreement as of the date set forth below.

	 	 	 	 	 	 
	Date:
	 
	 	By:	 

	 
	 	 	Name:	 

	 
	 	 	Title:	 

PLEASE COMPLETE, SIGN AND DATE THIS REGISTRATION RIGHTS SUBSTITUTION AGREEMENT AND RETURN IT
BY FACSIMILE AS SOON AS POSSIBLE, BUT IN NO EVENT LATER THAN 5:00 P.M. ON FRIDAY, MAY 4,
2007, WITH AN ORIGINAL SENT BY MAIL TO:

PolyMedix, Inc.

c/o Edward Smith, Corporate Secretary

170 N. Radnor-Chester Road; Suite 300

Radnor, PA 19087

Fax: (484) 598-2333 or (484) 598-2401

 

 

EXHIBIT A

SCHEDULE OF HOLDERS

	 	 	 	 	 
	 	 	 	 	Number of Shares of
	 	 	Number of Shares	 	Common Stock
	Name and Address	 	of Series 1 Stock	 	Underlying Warrants
	 
	 	 	 	 
	 
	 	 	 	 
	 
	 	 	 	 
	 
	 	 	 	 
	Total

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