Document:

EX-10.12

 Exhibit 10.12 

ONE TOWER PLACE 

LEASE 
 AP3-SF2 CT SOUTH, LLC, 
 a Delaware limited liability company 

as Landlord, 
 and 

APPLIED MOLECULAR TRANSPORT INC., 

a Delaware corporation 
 as Tenant

  

 SUMMARY OF BASIC LEASE INFORMATION 

This Summary of Basic Lease Information (“Summary”) is hereby incorporated into and made a part of the attached Lease. Each
reference in the Lease to any term of this Summary shall have the meaning as set forth in this Summary for such term. In the event of a conflict between the terms of this Summary and the Lease, the terms of the Lease shall prevail. Any capitalized
terms used herein and not otherwise defined herein shall have the meaning as set forth in the Lease. 
  

					
	 TERMS OF LEASE
 (References are
to the Lease)
	  	DESCRIPTION
	1	 	Date	  	December 18, 2016
			
	2	 	Landlord	  	 AP3-SF2 CT SOUTH, LLC

a Delaware limited liability company

			
	3	 	Address of Landlord (Section 24.19):	  	 For notices to Landlord:
  

AP3-SF2 CT South, LLC

4380 La Jolla Village Drive, Suite 230
 San Diego, CA 92121

Attention: W. Neil Fox, CEO
  

with a copy to:
  

Allen Matkins Leck Gamble Mallory & Natsis LLP
 501 West
Broadway, 15th Floor
 San Diego, California 92101
 Attention:
Martin L. Togni, Esq.
  
 For payment of Rent only:

 
 AP3-SF2 CT South LLC

Dept. LA 24484
 Pasadena, CA 91185-4484

			
	4	 	Tenant	  	 APPLIED MOLECULAR TRANSPORT INC.,
 a Delaware
corporation

			
	5	 	Address of Tenant (Section 24.19):	  	 APPLIED MOLECULAR TRANSPORT INC.
 280 Utah
Avenue, Suite 250
 South San Francisco, CA 94080
 Attention:
CEO
 (Prior to Lease Commencement Date)
  

And
  

One Tower Place, Suite 850
 South San Francisco, California
94080
 Attention: CEO
 (After Lease Commencement
Date)

  
 -i- 

					
	 TERMS OF LEASE
 (References are
to the Lease)
	  	DESCRIPTION
	6	 	Premises (Article 1)	  	
			
		 	6.1	  	Approximately 18,748 rentable square feet of space located on the eighth (8th) floor of the Building (as defined below), as depicted on Exhibit A attached hereto.
			
		 	6.2	  	The Premises are located in the building whose address is One Tower Place, South San Francisco, California (the “Building”).
			
	7	 	Term (Article 2):	  	
			
		 	 7.1  Lease Term:
	  	Five (5) years and four (4) months.
			
		 	 7.2  Lease Commencement Date:
	  	The earlier of (i) the date Tenant commences business operations in the Premises, or (ii) the date the Premises are Ready for Occupancy (as defined in the Tenant Work Letter attached hereto as Exhibit B),
which Lease Commencement Date is anticipated to be March 29, 2017 (the “Anticipated Lease Commencement Date”).
			
		 	 7.3  Lease Expiration Date
	  	The last day of the month in which the eighty-eighth (88th) month anniversary of the Lease Commencement Date occurs.
			
	8	 	Base Rent (Article 3):	  	

  

													
	 Lease Period
	  	Annual Base Rent	 	  	Monthly Installment of
Base Rent	 	  	Monthly Rental Rate per
Rentable Square Foot	 
	 1-12
	  	$	1,199,122.00	 	  	$	99,926.84	 	  	$	5.33	 
	 13-24
	  	$	1,241,867.50	 	  	$	103,488.96	 	  	$	5.52	 
	 25-36
	  	$	1,284,612.90	 	  	$	107,051.08	 	  	$	5.71	 
	 37-48
	  	$	1,329,608.10	 	  	$	110,800.68	 	  	$	5.91	 
	 49-60
	  	$	1,376,853.10	 	  	$	114,737.76	 	  	$	6.12	 
	 61-72
	  	$	1,424,098.00	 	  	$	118,674.84	 	  	$	6.33	 
	 73 84
	  	$	1,473,592.80	 	  	$	122,799.40	 	  	$	6.55	 
	 85-88
	  	$	1,525,337.28	 	  	$	127,111.44	 	  	$	6.78	 

  

					
	9	 	Tenant’s Share of Operating Expenses, Tax Expenses and Utilities Costs (Section 4.2.6):	  	5.52% (18,748 rentable square feet within the Premises/339,791 rentable square feet within the Building).

  
 -ii- 

					
	 TERMS OF LEASE
 (References are
to the Lease)
	  	DESCRIPTION
	10	 	Security Deposit (Article 20):	  	$127,111.44
			
	11	 	Brokers (Section 24.25):	  	No broker represents Landlord. Newmark Cornish & Carey represents Tenant.
			
	12	 	Parking (Article 23):	  	A total of sixty (60) unreserved parking spaces (based on 3.2 unreserved parking spaces for every 1,000 rentable square feet of the Premises).

  
 -iii- 

 TABLE OF CONTENTS 
  

					
	 	  	Page	 
	 ARTICLE 1 PROJECT, BUILDING AND PREMISES
	  	 	1	 
		
	 ARTICLE 2 LEASE TERM
	  	 	4	 
		
	 ARTICLE 3 BASE RENT
	  	 	5	 
		
	 ARTICLE 4 ADDITIONAL RENT
	  	 	5	 
		
	 ARTICLE 5 USE OF PREMISES; HAZARDOUS MATERIALS; ODORS AND EXHAUST
	  	 	11	 
		
	 ARTICLE 6 SERVICES AND UTILITIES
	  	 	16	 
		
	 ARTICLE 7 REPAIRS
	  	 	17	 
		
	 ARTICLE 8 ADDITIONS AND ALTERATIONS
	  	 	18	 
		
	 ARTICLE 9 COVENANT AGAINST LIENS
	  	 	20	 
		
	 ARTICLE 10 INDEMNIFICATION AND INSURANCE
	  	 	21	 
		
	 ARTICLE 11 DAMAGE AND DESTRUCTION
	  	 	23	 
		
	 ARTICLE 12 CONDEMNATION
	  	 	24	 
		
	 ARTICLE 13 COVENANT OF QUIET ENJOYMENT
	  	 	24	 
		
	 ARTICLE 14 ASSIGNMENT AND SUBLETTING
	  	 	25	 
		
	 ARTICLE 15 SURRENDER; OWNERSHIP AND REMOVAL OF PERSONAL PROPERTY
	  	 	27	 
		
	 ARTICLE 16 HOLDING OVER
	  	 	28	 
		
	 ARTICLE 17 ESTOPPEL CERTIFICATES
	  	 	29	 
		
	 ARTICLE 18 SUBORDINATION
	  	 	29	 
		
	 ARTICLE 19 TENANT’S DEFAULTS; LANDLORD’S REMEDIES
	  	 	29	 
		
	 ARTICLE 20 SECURITY DEPOSIT
	  	 	32	 
		
	 ARTICLE 21 COMPLIANCE WITH LAW
	  	 	33	 
		
	 ARTICLE 22 ENTRY BY LANDLORD
	  	 	33	 
		
	 ARTICLE 23 PARKING
	  	 	33	 
		
	 ARTICLE 24 MISCELLANEOUS PROVISIONS
	  	 	34	 

 EXHIBITS 
  

			
	Exhibit A	  	 Outline of Floor Plan on Premises

	Exhibit A-1	  	 Site Plan of Project

	Exhibit B	  	 Tenant Work Letter

	Exhibit C	  	 Confirmation of Lease Terms/Amendment to Lease

	Exhibit D	  	 Rules and Regulations

	Exhibit E	  	 Control Areas for Hazardous Materials Storage

	Exhibit F	  	 General Storage Area

	Rider	  	Extension Option Rule

  
 (i) 

 INDEX 
  

					
	 	  	Page(s)	 
	 Abated Rent
	  	 	5	 
	 Additional Rent
	  	 	6	 
	 Affected Areas
	  	 	13	 
	 Affiliate Assignee
	  	 	27	 
	 Alterations
	  	 	18	 
	 Anticipated Lease Commencement Date
	  	 	ii	 
	 Approved Working Drawings
	  	 	Exhibit B	 
	 Base Rent
	  	 	5	 
	 Base, Shell and Core
	  	 	Exhibit B	 
	 Brokers
	  	 	37	 
	 Building
	  	 	ii	 
	 Calendar Year
	  	 	6	 
	 CC&Rs
	  	 	2	 
	 Confirmation/Amendment
	  	 	Exhibit C	 
	 Conservation Costs
	  	 	7	 
	 Construction
	  	 	38	 
	 Construction Drawings
	  	 	Exhibit B	 
	 Contractor
	  	 	Exhibit B	 
	 Corrective Action
	  	 	7	 
	 Corrective Action
	  	 	13	 
	 Cost Pools
	  	 	7	 
	 Documents
	  	 	12	 
	 Environmental Law
	  	 	12	 
	 Environmental Permits
	  	 	12	 
	 Estimate
	  	 	9	 
	 Estimate Statement
	  	 	9	 
	 Estimated Expenses
	  	 	9	 
	 Excluded Changes
	  	 	33	 
	 Exercise Date
	  	 	Rider	 
	 Exercise Notice
	  	 	Rider	 
	 Exit Survey
	  	 	28	 
	 Expense Year
	  	 	6	 
	 Extension Option
	  	 	Rider	 
	 Extension Rider
	  	 	Rider	 
	 Fair Market Rental Rate
	  	 	Rider	 
	 Final Space Plan
	  	 	Exhibit B	 
	 First Offer Economic Terms
	  	 	3	 
	 First Offer Notice
	  	 	3	 
	 First Offer Space
	  	 	3	 
	 Fitness Center
	  	 	39	 
	 Force Majeure
	  	 	36	 
	 Free Rent Day
	  	 	4	 
	 Hazardous Materials
	  	 	12	 
	 Hazardous Materials List
	  	 	12	 
	 Holidays
	  	 	16	 
	 Interest Notice
	  	 	Rider	 
	 Interest Rate
	  	 	11	 
	 Landlord
	  	 	1	 
	 Landlord Parties
	  	 	14	 
	 Landlord’s Work
	  	 	Exhibit B-1	 
	 Lease
	  	 	1	 

  
 (ii) 

					
	 	  	Page(s)	 
	 Lease Commencement Date
	  	 	4	 
	 Lease Expiration Date
	  	 	4	 
	 Lease Term
	  	 	4	 
	 Lease Year
	  	 	4	 
	 Notices
	  	 	37	 
	 OFAC
	  	 	37	 
	 Official Records
	  	 	11	 
	 Operating Expenses
	  	 	6	 
	 Option Rent
	  	 	Rider	 
	 Option Rent Notice
	  	 	Rider	 
	 Option Term
	  	 	Rider	 
	 Other Buildings
	  	 	10	 
	 Other Future Building
	  	 	1	 
	 Outside Agreement Date
	  	 	Rider	 
	 PAC
	  	 	39	 
	 Parking Area
	  	 	1	 
	 Parking Operator
	  	 	34	 
	 Premises
	  	 	1	 
	 Premises Systems
	  	 	18	 
	 Project
	  	 	1	 
	 Proposition 13
	  	 	8	 
	 Release
	  	 	12	 
	 Rent
	  	 	6	 
	 Rent Commencement Date
	  	 	1	 
	 rentable square feet
	  	 	2	 
	 Revenue Code
	  	 	25	 
	 Security Deposit
	  	 	32	 
	 Statement
	  	 	9	 
	 Subject Space
	  	 	25	 
	 Subleasing Costs
	  	 	26	 
	 Summary
	  	 	i	 
	 Systems and Equipment
	  	 	7	 
	 Tax Expenses
	  	 	8	 
	 Tenant
	  	 	1	 
	 Tenant Delays
	  	 	Exhibit B	 
	 Tenant Improvements
	  	 	Exhibit B	 
	 Tenant Work Letter
	  	 	Exhibit B	 
	 Tenant’s Parties
	  	 	12	 
	 Tenant’s Share
	  	 	8	 
	 Transfer Notice
	  	 	25	 
	 Transfer Premium
	  	 	26	 
	 Transferee
	  	 	25	 
	 Transfers
	  	 	25	 
	 trash
	  	 	40	 
	 Utilities Costs
	  	 	9	 
	 Wi-Fi Network
	  	 	20	 
	 Working Drawings
	  	 	Exhibit B	 

  
 -iii- 

 LEASE 

This Lease, which includes the preceding Summary and the exhibits attached hereto and incorporated herein by this reference (the Lease, the
Summary and the exhibits to be known sometimes collectively hereafter as the “Lease”), dated as of the date set forth in Section 1 of the Summary, is made by and between AP3-SF2 CT SOUTH,
LLC, a Delaware limited liability company (“Landlord”), and APPLIED MOLECULAR TRANSPORT INC., a Delaware corporation (“Tenant”). 

ARTICLE 1 

PROJECT, BUILDING AND PREMISES 

1.1 Project, Building and Premises. 

1.1.1 Premises. Upon and subject to the terms, covenants and conditions hereinafter set forth in this Lease, Landlord hereby leases to
Tenant and Tenant hereby leases from Landlord the premises described in Section 6.1 of the Summary (the “Premises”), which Premises are located in the Building (as defined in Section 6.2 of the Summary) and located within
the Project (as defined below). The floor plan of the Premises is attached hereto as Exhibit A. 
 1.1.2 Building and
Project. The Building consists of twelve (12) floors with a total of 339,791 rentable square feet and is part of a multi-building commercial project known as “Genesis South San Francisco”, located on 8.4 acres of land in the City
of South San Francisco. The term “Project” as used in this Lease, shall mean, collectively: (i) the Building; (ii) the other existing building located at Two Tower Place within the site which is not owned by Landlord (the
“Other Future Building”); (iii) any outside plaza areas, walkways, driveways, courtyards, public and private streets, transportation facilitation areas and other improvements and facilities now or hereafter constructed surrounding
and/or servicing the Building and/or the Other Future Building, which are designated from time to time by Landlord (and/or any other owners of the Project) as common areas appurtenant to or servicing the Building, and any such other improvements;
(iii) any additional buildings, improvements, facilities and common areas which Landlord (any other owners of the Project and/or any common area association formed by Landlord, Landlord’s predecessor-in-interest and/or Landlord’s assignee for the Project) may add thereto from time to time within or as part of the Project; and (iv) the land upon which any of the foregoing are
situated. The site plan depicting the current configuration of the Project is attached hereto as Exhibit A-1. The Building, as well as the Other Future Building, is served by a parking facility
located at Three Tower Place (“Parking Facility”). Notwithstanding the foregoing or anything contained in this Lease to the contrary, (1) Landlord has no obligation to expand or otherwise make any improvements within the
Project, including, without limitation, any of the outside plaza areas, walkways, driveways, courtyards, public and private streets, transportation facilitation areas and other improvements and facilities which may be depicted on Exhibit A-1 attached hereto (as the same may be modified by Landlord (and/or any other owners of the Project) from time to time without notice to Tenant), other than Landlord’s obligations (if any) specifically
set forth in the Tenant Work Letter attached hereto as Exhibit B, and (2) Landlord (and/or any other owners of the Project) shall have the right from time to time to include or exclude any improvements or facilities within the
Project, at such party’s sole election, as more particularly set forth in Section 1.1.3 below. 
 1.1.3 Tenant’s and
Landlord’s Rights. Tenant shall have the right to the nonexclusive use of the common corridors and hallways, stairwells, elevators (if any), restrooms and other public or common areas located within the Building, and the non-exclusive use of those areas located on the Project that are designated by Landlord (and/or any other owners of the Project) from time to time as common areas for the Building; provided, however, that
(i) Tenant’s use thereof shall be subject to (A) the provisions of any covenants, conditions and restrictions regarding the use thereof now or hereafter recorded against the Project, and (B) such reasonable, non-discriminatory rules and regulations as Landlord may make from time to time (which shall be provided in writing to Tenant), and (ii) Tenant may not go on the roof of Building or the Other Future Building
without Landlord’s prior consent (which may be withheld in Landlord’s sole and absolute (but good faith) discretion) and without otherwise being accompanied by a representative of Landlord. Landlord (and/or any other owners of the Project)
reserves the right from time to time to use any of the common areas of the Project, and the roof, risers and conduits of the Building and the Other Future Building for telecommunications and/or any other purposes, and to do any of the following, so
long as the same does 

 
not unreasonably interfere with Tenant’s use of or access to the Premises or Tenant’s parking rights and does not materially increase the obligations or materially decrease the rights
of Tenant under this Lease: (1) make any changes, additions, improvements, repairs and/or replacements in or to the Project or any portion or elements thereof, including, without limitation, (x) changes in the location, size, shape and
number of driveways, entrances, loading and unloading areas, ingress, egress, direction of traffic, landscaped areas, walkways, public and private streets, plazas, courtyards, transportation facilitation areas and common areas, and
(y) expanding or decreasing the size of the Project and any common areas and other elements thereof, including adding, deleting and/or excluding buildings (including the Other Future Building) thereon and therefrom; (2) close temporarily
any of the common areas while engaged in making repairs, improvements or alterations to the Project; (3) retain and/or form a common area association or associations under covenants, conditions and restrictions to own, manage, operate,
maintain, repair and/or replace all or any portion of the landscaping, driveways, walkways, public and private streets, plazas, courtyards, transportation facilitation areas and/or other common areas located outside of the Building and the Other
Future Building and, subject to Article 4 below, include the common area assessments, fees and taxes charged by the association(s) and the cost of maintaining, managing, administering and operating the association(s), in Operating Expenses or Tax
Expenses; and (4) perform such other acts and make such other changes with respect to the Project as Landlord may, in the exercise of good faith business judgment, deem to be appropriate. 

1.2 Condition of Premises. Except as expressly set forth in this Lease and in the Tenant Work Letter, Landlord shall not be obligated to
provide or pay for any improvement, remodeling or refurbishment work or services related to the improvement, remodeling or refurbishment of the Premises, and Tenant shall accept the Premises in its “As Is” condition on the Lease
Commencement Date: provided, however, in the event that, during the first twelve (12) months of the Lease Term, the Base, Shell and Core of the Building (as defined in Section 1 of Exhibit B) without regard to any alterations or other
improvements to be constructed or installed by Tenant in the Premises or Tenant’s use of the Premises, (A) does not comply with applicable laws, seismic, fire and life safety codes, and the ADA, in effect as of the date hereof, or
(B) contains defects, then Landlord shall be responsible, at its sole cost and expense which shall not be included in Operating Expenses (except as otherwise permitted in Section 4.2 hereof), for correcting any such non-compliance to the extent required by applicable laws, and/or correcting any such defects as soon as reasonably possible after receiving notice thereof from Tenant; provided, however, that if Tenant fails to give
Landlord written notice of any such defects described in clause (B) hereinabove within twelve (12) months after the Lease Commencement Date, then the correction of any such defects shall, subject to Landlord’s repair obligations in
Section 7.2 hereof (and to the extent such correction is a responsibility of Tenant pursuant to Section 7.1 hereof), be Tenant’s responsibility at Tenant’s sole cost and expense. Pursuant to Civil Code Section 1938, Landlord
states that, as of the date hereof, the Premises has not undergone inspection by a Certified Access Specialist (“CASp”) to determine whether the Premises meet all applicable construction-related accessibility standards under
California Civil Code Section 55.53. Tenant also acknowledges that, except as otherwise expressly set forth in this Lease, neither Landlord nor any agent of Landlord has made any representation or warranty with respect to the Premises, the
Building, or the Project or their condition, or with respect to the suitability thereof for the conduct of Tenant’s business (including, but not limited to, any zoning/conditional use permit requirements which shall be Tenant’s
responsibility and Tenant’s failure to obtain any such zoning/use permits (if any are required) shall not affect Tenant’s obligations under this Lease). Subject to Landlord’s delivery obligations hereunder, the taking of possession of
the Premises by Tenant shall conclusively establish that the Premises (including the Tenant Improvements therein), the Building and the Project were at such time complete and in good, sanitary and satisfactory condition and without any obligation on
Landlord’s part to make any alterations, upgrades or improvements thereto. 
 1.3 Rentable Square Feet. The rentable square feet
of the Premises is approximately as set forth in Section 6.1 of the Summary. For purposes hereof, the rentable square feet of the Premises and the Building shall be reasonably calculated by Landlord’s architect. The rentable square feet of
the Premises and the Building are subject to verification by Landlord’s architect within thirty (30) days of the Lease Commencement Date and such verification shall be made in accordance with the provisions of this Section 1.3.
Tenant’s architect may consult with Landlord’s planner/designer regarding such verification, except to the extent it relates to the rentable square feet of the Building; provided, however, the determination of Landlord’s architect
shall be conclusive and binding upon the parties. If Landlord’s architect determines that the rentable square footage amounts shall be different from those set forth in this Lease, all amounts, percentages and figures appearing or referred to
in this Lease based upon such incorrect rentable square footage (including, without limitation, the amount of the Base Rent and Tenant’s Share) shall be modified in accordance with such determination; provided, however, in no event shall the
rentable square footage hereunder exceed 19,000 rentable square feet. If such determination is made, it will be confirmed in writing by Landlord to Tenant. 

  
 -2- 

 1.4 Right of First Offer. Commencing ninety (90) days after the date hereof
(“ROFO Trigger Date”) and continuing throughout the entire Lease Term, Tenant shall have an ongoing (subject to the terms hereof) right of first offer to Lease space contiguous to the Premises located on the eighth (8th) floor of
the Building (“First Offer Space”); provided, however, that in the event Landlord enters into a lease for space on the eighth (8th) floor of the Building with a third party on or before the ROFO Trigger Date, then such thirty party
tenant shall be deemed to be a ROFO Superior right and Tenant’s right of first offer shall be subject and subordinate to the rights of such third party tenant. Notwithstanding the foregoing (i) such first offer right of Tenant shall become
effective only following the expiration or earlier termination of any existing lease pertaining to the First Offer Space, including any renewal or extension of such existing or future lease, whether or not such renewal or extension is pursuant to an
express written provision in such lease, and regardless of whether any such renewal or extension is consummated pursuant to a lease amendment or a new lease, and (ii) Tenant’s first offer right shall be subordinate and secondary to all
currently existing rights of expansion, first refusal, first offer or similar rights previously granted to (A) the tenants of any existing leases and (B) any other tenant of the Project (the rights described in items (i) and (ii),
above to be known collectively as “ROFO Superior Rights”). Tenant’s right of first offer shall be on the terms and conditions set forth in this Section 1.4. As of the date of this Lease, Landlord acknowledges and agrees
that no ROFO Superior Rights exist. 
 1.4.1 Procedure for Offer. Landlord shall notify Tenant (the “First Offer
Notice”) from time to time when Landlord determines that Landlord shall commence the marketing of any First Offer Space because such space shall become available for lease to third parties, where no holder of a ROFO Superior Right has
agreed to lease such space. The First Offer Notice shall describe the space so offered to Tenant and shall set forth Landlord’s proposed material economic terms and conditions applicable to Tenant’s lease of such space (collectively, the
“First Offer Economic Terms”), including the proposed term of lease and the proposed rent payable for the First Offer Space. Notwithstanding the foregoing, Landlord’s obligation to deliver the First Offer Notice shall not apply
during the last twelve (12) months of the initial Term unless Tenant has delivered an Exercise Notice to Landlord pursuant to Rider No. 1. 

1.4.2 Procedure for Acceptance. If Tenant wishes to exercise Tenant’s right of first offer with respect to the space described in the
First Offer Notice, then within five (5) business days after delivery of the First Offer Notice to Tenant, Tenant shall deliver an unconditional irrevocable notice to Landlord of Tenant’s exercise of its right of first offer with respect
to the entire space described in the First Offer Notice, and the First Offer Economic Terms shall be as set forth in the First Offer Notice. If Tenant does not unconditionally exercise its right of first offer within the five (5) business day
period, then Landlord shall, for a period of six three (3) months, be free to lease the space described in the First Offer Notice to anyone to whom Landlord desires on any terms Landlord desires; provided, however, that if Landlord, intends to
enter into a lease upon ROFO Economic Terms which are, in the aggregate, materially more favorable to a prospective tenant than those ROFO Economic Terms proposed by Landlord in the First Offer Notice to Tenant, then Landlord shall first deliver
written notice to Tenant (“ROFO Second Chance Notice”) providing Tenant with the opportunity to lease the First Offer Space on such more favorable ROFO Economic Terms. For purposes hereof, ROFO Economic Terms shall be materially
more favorable to a third party if such ROFO Economic Terms reflect a net effective rental rate (including any rent abatement and Tenant Improvement costs/allowance and any other economic concessions) less than ninety-five (95%) of the net effective
rental rate for such First Offer Space as those proposed by Landlord in the First Offer Notice to Tenant. Tenant’s failure to elect to lease the First Offer Space upon such more favorable ROFO Economic Terms by written notice to Landlord within
three (3) business days after Tenant’s receipt of such ROFO Second Chance Notice from Landlord shall be deemed to constitute Tenant’s election not to lease such space upon such more favorable ROFO Economic Terms, in which case
Landlord shall be entitled to lease such space to any third (3rd) party on any terms Landlord desires, subject to Landlord’s obligation to deliver Tenant a further ROFO Second Chance Notice under the circumstances set forth in the preceding two
sentences. Notwithstanding anything above to the contrary, in no event shall Landlord be obligated to provide Tenant with a Second Chance Notice if, at the time Landlord would otherwise be obligated to provide such Second Chance Notice to Tenant,
the prospective third party tenant has an S&P credit rating equal to or greater than “BBB”. Notwithstanding anything to the contrary contained herein, Tenant must elect to exercise its right of first offer, if at all, with respect to
all of the space comprising the First Offer Space offered by Landlord to Tenant at any particular time, and Tenant may not elect to lease only a portion thereof or object to any of the First Offer Economic Terms. 

  
 -3- 

 1.4.3 Construction of First Offer Space. Tenant shall take the First Offer Space in
its “as-is” condition (except as otherwise provided in the First Offer Economic Terms), and Tenant shall be entitled to construct improvements in the First Offer Space in accordance with the
provisions of Article 8 of this Lease. 
 1.4.4 Lease of First Offer Space. If Tenant timely and properly exercises Tenant’s
right to lease the First Offer Space as set forth herein, Landlord and Tenant shall execute an amendment adding such First Offer Space to this Lease upon the same non-economic terms and conditions as
applicable to the initial Premises, and the economic terms and conditions as provided in this Section 1.4. Unless otherwise specified in the First Offer Economic Terms, Tenant shall commence payment of rent for the First Offer Space and the
Term of the First Offer Space shall commence upon the date of delivery of such space to Tenant. The Lease Term for the First Offer Space shall be as provided in the First Offer Economic Terms. 

1.4.5 No Defaults. The rights contained in this Section 1.4 may be exercised by the Original Tenant and any Affiliate Assignee (but
not any other assignee or sublessee of the Original Tenant’s interest (or Affiliate Assignee’s interest) in this Lease) if the Original Tenant (or such Affiliate Assignee) occupies the entire Premises as of the date of the First Offer
Notice (or Affiliate Assignee’s interest). Tenant shall not have the right to lease First Offer Space as provided in this Section 1.4 if, as of the date of the First Offer Notice, or, at Landlord’s option, as of the scheduled date of
delivery of such First Offer Space to Tenant, Tenant is in default under this Lease beyond the expiration of all applicable notice and cure periods. 

1.4.6 Remedy. The sole remedy of Tenant for a breach by Landlord of its obligations under this Section 1.4 shall be an action
against Landlord for direct damages (excluding consequential and punitive damages), and for a temporary restraining order, preliminary injunction, injunction, or specific performance, but no other remedy, equitable or otherwise. 

ARTICLE 2 

LEASE TERM 
 The
terms and provisions of this Lease shall be effective as of the date of this Lease except for the provisions of this Lease relating to the payment of Rent, and Tenant’s obligations under Articles 7, 10.1, and 21 (or any other performance
obligation that tenants typically perform only after the Commencement Date). The term of this Lease (the “Lease Term”) shall be as set forth in Section 7.1 of the Summary and shall commence on the date (the “Lease
Commencement Date”) set forth in Section 7.2 of the Summary (subject, however, to the terms of the Tenant Work Letter), and shall terminate on the date (the “Lease Expiration Date”) set forth in Section 7.3 of the
Summary, unless this Lease is sooner terminated as hereinafter provided. For purposes of this Lease, the term “Lease Year” shall mean each consecutive twelve (12) month period during the Lease Term, provided that the last Lease Year
shall end on the Lease Expiration Date. If Landlord does not deliver possession of the Premises to Tenant Ready for Occupancy on or before the anticipated Lease Commencement Date (as set forth in Section 7.2(ii) of the Summary), Landlord shall
not be subject to any liability nor shall the validity of this Lease nor the obligations of Tenant hereunder be affected; provided; however, if Landlord does not deliver possession of the Premises to Tenant Ready for Occupancy on or before
May 1, 2017, but subject to deferral for Tenant Delays in accordance with Section 4.2 of the Work Letter) and Force Majeure delays (as defined in Section 24.17 hereof (but limited as further defined below and not to exceed thirty
(30) days of Force Majeure Delays)), then Tenant shall receive one (1) Free Rent Day (as hereinafter defined) for each day that elapses from and after May 1, 2017 until and including the date on which Landlord delivers possession of
the Premises to Tenant Ready for Occupancy, up to a maximum of thirty-one (31) days and shall receive two (2) Free Rent Days for each day that elapses from and after June 1, 2017 until and
including the date on which Landlord delivers possession of the Premises to Tenant Ready for Occupancy. If Landlord does not deliver possession of the Premises to Tenant Ready for Occupancy on or before July 1, 2017 (as such date may be
extended due to Tenant Delays and Force Majeure Delays (but not to exceed thirty (30) days of Force Majeure Delays) then Tenant shall have the right to terminate this Lease by written notice to Landlord, whereupon all monies previously paid by
Tenant to Landlord shall be reimbursed to Tenant. A “Free Rent Day” means a day for which Tenant has no obligation to pay either Rent or Operating Expenses after the Lease Commencement Date, and all Free Rent Days shall be applied
as soon as possible following the Lease Commencement Date. Notwithstanding anything above to the contrary, (i) for purposes of this Article 2, Force Majeure Delays shall be limited to governmental strikes, acts of God, civil unrest, terrorism,
war, natural disaster and similar causes beyond Landlord’s reasonable control and (ii) any delay by Landlord 

  
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beyond forty-five (45) days in substantially completing the cold room portion of the Premises shall entitle Tenant one (1) day of Free Rent Day for each day of such delay. If the Lease
Commencement Date is a date which is other than the Anticipated Lease Commencement Date set forth in Section 7.2(ii) of the Summary, then, following the Lease Commencement Date, Landlord shall deliver to Tenant an amendment to lease in the form
attached hereto as Exhibit C, attached hereto, setting forth, among other things, the Lease Commencement Date, and the Lease Expiration Date, and Tenant shall execute and return such amendment to Landlord within ten (10) business
days after Tenant’s receipt thereof. If Tenant fails to execute and return the amendment within such 10-business day period, Tenant shall be deemed to have approved and confirmed the dates set forth
therein, provided that such deemed approval shall not relieve Tenant of its obligation to execute and return the amendment (and such failure shall constitute a default by Tenant hereunder after the expiration of applicable notice and cure periods).

 ARTICLE 3 

BASE RENT 
 Tenant
shall pay, without notice or demand, to Landlord at the address set forth in Section 3 of the Summary, or at such other place as Landlord may from time to time designate in writing, in currency or a check for currency which, at the time of
payment, is legal tender for private or public debts in the United States of America, base rent (“Base Rent”) as set forth in Section 8 of the Summary, payable in equal monthly installments as set forth in Section 8 of the
Summary in advance on or before the first day of each and every month during the Lease Term, without any setoff or deduction whatsoever. Concurrently with Tenant’s execution of this Lease, Tenant shall deliver to Landlord an amount equal to
$121,862.00, which amount shall be comprised of the following: (i) the Base Rent payable by Tenant for the Premises for the first (1st) full month of the Lease Term (i.e., $99,926.84); and (ii) the Estimated Expenses (as defined below)
payable by Tenant for the Premises for the first (1st) full month of the Lease Term (i.e., $21,935.16). If any rental payment date (including the Lease Commencement Date) falls on a day of the month other than the first day of such month or if any
rental payment is for a period which is shorter than one month, then the rental for any such fractional month shall be a proportionate amount of a full calendar month’s rental based on the proportion that the number of days in such fractional
month bears to the number of days in the calendar month during which such fractional month occurs. All other payments or adjustments required to be made under the terms of this Lease that require proration on a time basis shall be prorated on the
same basis. 
 Notwithstanding anything to the contrary contained herein and so long as Tenant is not then in default under this Lease
(beyond the expiration of all applicable notice and cure periods), Landlord hereby agrees to abate Tenant’s obligation to pay Tenant’s monthly Base Rent for the second (2nd), third (3rd), fourth (4th) and fifth (5th) full months of the
initial Lease Term (collectively the “Abated Rent”). During such abatement period, Tenant shall still be responsible for the payment of all of its other monetary obligations under this Lease. In the event of a default by Tenant
under the terms of this Lease that results in early termination pursuant to the provisions of Article 19 of this Lease, then as a part of the recovery set forth in Article 19 of this Lease, Landlord shall be entitled to the recovery of the
unamortized amount of the Abated Rent that was abated under the provisions of this Article 3. 
 ARTICLE 4 

ADDITIONAL RENT 

4.1 Additional Rent. In addition to paying the Base Rent specified in Article 3 above, Tenant shall pay as additional rent the sum of
the following: (i) Tenant’s Share (as such term is defined below) of the annual Operating Expenses allocated to the Building (pursuant to Section 4.3.4 below); plus (ii) Tenant’s Share of the annual Tax Expenses allocated to
the Building (pursuant to Section 4.3.4 below); plus (iii) Tenant’s Share of the annual Utilities Costs allocated to the Building (pursuant to Section 4.3.4 below). Landlord currently estimates that such amounts will be $1.17 per
rentable square foot per month in 2017, excluding utilities to the Premises; provided, however, that such estimate shall not be binding on Landlord in the event that the actual amounts are in excess of such estimate. Such additional rent, together
with any and all other amounts payable by Tenant to Landlord pursuant to the terms of this Lease (including, without limitation, pursuant to Article 6), shall be hereinafter collectively referred to as the “Additional Rent.” The
Base Rent and Additional Rent are herein collectively referred to as the “Rent.” All amounts due under this Article 4 as Additional Rent shall be payable for the same periods and in the same manner, time and place as the Base Rent.
Without limitation on other obligations of Tenant which shall survive the expiration of the Lease Term, the obligations of Tenant to pay the Additional Rent provided for in this Article 4 shall survive the expiration of the Lease Term. 

  
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 4.2 Definitions. As used in this Article 4, the following terms shall have the
meanings hereinafter set forth: 
 4.2.1 “Calendar Year” shall mean each calendar year in which any portion of the Lease
Term falls, through and including the calendar year in which the Lease Term expires. 
 4.2.2 “Expense Year” shall mean each
Calendar Year. 
 4.2.3 “Operating Expenses” shall mean all expenses, costs and amounts of every kind and nature which
Landlord shall pay during any Expense Year because of or in connection with the ownership, management, maintenance, repair, restoration or operation of the Project, including, without limitation, any amounts paid for: (i) the cost of operating,
maintaining, repairing, renovating and managing the utility systems, lab systems, central plant, mechanical systems, sanitary and storm drainage systems, any elevator systems (if applicable) and all other “Systems and Equipment” (as
defined in Section 4.2.4 of this Lease), and the cost of supplies and equipment and maintenance and service contracts in connection therewith; (ii) the cost of licenses, certificates, permits and inspections, and the cost of contesting the
validity or applicability of any governmental enactments which may affect Operating Expenses, and the costs incurred in connection with implementation and operation (by Landlord or any common area association(s) formed for the Project) of any
transportation system management program or similar program; (iii) the cost of insurance carried by Landlord, in such amounts as Landlord may reasonably determine or as may be required by any mortgagees of any mortgage or the lessor of any
ground lease affecting the Project; (iv) the cost of landscaping, relamping, supplies, tools, equipment and materials, and all fees, charges and other costs (including consulting fees, legal fees and accounting fees) incurred in connection with
the management, operation, repair and maintenance of the Project; (v) any equipment rental agreements or management agreements (including the cost of any property management and accounting fee; provided that the property management and
accounting fee payable by Tenant shall not exceed three percent (3%) of the Base Rent); (vi) wages, salaries and other compensation and benefits of all persons to the extent they are engaged in the operation, management, maintenance or security of
the Project, and employer’s Social Security taxes, unemployment taxes or insurance, and any other taxes which may be levied on such wages, salaries, compensation and benefits; (vii) payments under any easement, license, operating
agreement, declaration, restrictive covenant, underlying or ground lease (excluding rent), or instrument pertaining to the sharing of costs by the Project (including but not limited to, the CC&Rs described in Article 5 hereof); (viii) the cost
of janitorial service, trash removal (provided, however, Operating Expenses shall not include the cost of janitorial services and trash removal services provided to the Premises or the premises of other tenants of the Building and/or the Project or
the cost of replacing light bulbs, lamps, starters and ballasts for lighting fixtures in the Premises and the premises of other tenants in the Building and/or the Project to the extent such services are directly provided and paid for by Tenant
pursuant to Section 6.6 below), alarm and security service, if any, window cleaning, replacement of wall and floor coverings, ceiling tiles and fixtures in lobbies, corridors, restrooms and other common or public areas or facilities,
maintenance and replacement of curbs and walkways, repair to roofs and re-roofing; (ix) amortization (including interest on the unamortized cost) of the cost of acquiring or the rental expense of personal
property used in the maintenance, operation and repair of the Project; (x) the cost of any capital improvements or other costs (I) which are intended as a labor-saving device or to effect other economies in the operation or maintenance of
the Project or which are otherwise permitted hereunder, (II) made to the Project or any portion thereof after the Lease Commencement Date that are required under any governmental law or regulation, or (III) which are Conservation Costs (as
defined below) and/or which are reasonably determined by Landlord to be in the best interests of the Project; provided, however, that if any such cost described in (I), (II) or (III) above, is a capital expenditure, such cost shall be amortized
(including interest on the unamortized cost) over the useful life of the item as Landlord shall reasonably determine; and (xi) the costs and expenses of complying with, or participating in, conservation, recycling, sustainability, energy
efficiency, waste reduction or other programs or practices implemented or enacted from time to time at the Building and/or Project, including, without limitation, in connection with any LEED (Leadership in Energy and Environmental Design) rating or
compliance system or program, including that currently coordinated through the U.S. Green Building Council or Energy Star rating and/or compliance system or program (collectively, “Conservation Costs”). If Landlord is not furnishing
any particular work or service (the cost of which, if performed by Landlord, would be included in Operating Expenses) to a tenant who has undertaken to perform such work or service in lieu of the performance thereof by Landlord, Operating Expenses
shall be deemed to be increased by an 

  
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amount equal to the additional Operating Expenses which would reasonably have been incurred during such period by Landlord if it had at its own expense furnished such work or service to such
tenant. If any of (x) the Building, (y) the Other Future Building (but only during the period of time the same are included by Landlord within the Project) and (z) any additional buildings are added to the Project pursuant to
Section 1.1.3 above (but only during the period of time after such additional buildings have been fully constructed and ready for occupancy and are included by Landlord within the Project) are less than ninety-five percent (95%) occupied during
all or a portion of any Expense Year, Landlord shall make an appropriate adjustment to the variable components of Operating Expenses for such year or applicable portion thereof, employing sound accounting and management principles, to determine the
amount of Operating Expenses that would have been paid had the Building, such Other Future Building and such additional buildings (if any) been ninety-five percent (95%) occupied; and the amount so determined shall be deemed to have been the amount
of Operating Expenses for such year, or applicable portion thereof. 
 Subject to the provisions of Section 4.3.4 below, Landlord shall
have the right, from time to time, to equitably allocate some or all of the Operating Expenses (and/or Tax Expenses and Utilities Costs) between the Building and the Other Future Building and/or among different tenants of the Project and/or among
the Other Buildings (as defined in Section 4.3.4 below, if any, as and when such different buildings are constructed and added to (and/or excluded from) the Project (the “Cost Pools”). Such Cost Pools may also include an
allocation of certain Operating Expenses (and/or Tax Expenses and Utilities Costs) within or under covenants, conditions and restrictions affecting the Project. In addition, subject to the provisions of Section 4.3.4 below, Landlord shall have
the right from time to time, in its reasonable discretion, to include future buildings in the Project for purposes of determining Operating Expenses, Tax Expenses and Utilities Costs and/or the provision of various services and amenities thereto,
including allocation of Operating Expenses, Tax Expenses and Utilities Costs in any such Cost Pools. 
 Notwithstanding the foregoing,
Operating Expenses shall not, however, include: (A) costs of leasing commissions, attorneys’ fees and other costs and expenses incurred in connection with negotiations or disputes with present or prospective tenants or other occupants of
the Project; (B) costs (including permit, license and inspection costs) incurred in renovating or otherwise improving, decorating or redecorating rentable space for other tenants or vacant rentable space; (C) costs incurred due to the
violation by Landlord of the terms and conditions of any lease of space in the Project; (D) costs of overhead or profit increment paid to Landlord or to subsidiaries or affiliates of Landlord for services in or in connection with the Project to
the extent the same exceeds the costs of overhead and profit increment included in the costs of such services which could be obtained from third parties on a competitive basis; (E) costs of interest on debt or amortization on any mortgages, and
rent payable under any ground lease of the Project; (F) Utilities Costs; (G) Tax Expenses; (H) costs occasioned by casualties or condemnation; (I) costs to correct violation of law applicable to the Premises or the Project on the
Commencement Date: (J) costs incurred in connection with the presence of any Hazardous Materials, except to the extent caused by the release or emission of the Hazardous Material in question by Tenant; (K) expense reserves; (L) costs
which could properly be capitalized under generally accepted accounting principles, except as specifically provided in 4.2.3(x), above, and only to the extent amortized over the useful life of the capital item in question; (M) costs for
services not provided to Tenant under this Lease or are of a nature that are payable directly by Tenant; (N) profit by Landlord for managing or administering the Project except as set forth in Section 4.2.3(v) above; and (O) any costs
related to construction of the Other Buildings or completion of the work described in Exhibit B or to complete Landlord’s planned renovation or redevelopment of the Project. 

4.2.4 “Systems and Equipment” shall mean any plant (including any central plant), machinery, transformers, duct work, cable,
wires, and other equipment, facilities, and systems designed to supply heat, ventilation, air conditioning and humidity or any other services or utilities, or comprising or serving as any component or portion of the electrical, gas, steam, plumbing,
sprinkler, communications, alarm, lab, security, or fire/life safety systems or equipment, or any other mechanical, electrical, electronic, computer or other systems or equipment which serve the Building and/or any other building in the Project in
whole or in part. 
 4.2.5 “Tax Expenses” shall mean all federal, state, county, or local governmental or municipal taxes,
fees, assessments, charges or other impositions of every kind and nature, whether general, special, ordinary or extraordinary, (including, without limitation, real estate taxes, general and special assessments, transit assessments, fees and taxes,
child care subsidies, fees and/or assessments, job training subsidies, fees and/or assessments, open space fees and/or assessments, housing subsidies and/or housing fund fees or assessments, public art fees and/or assessments, leasehold taxes or
taxes based upon the receipt of rent, including gross receipts or sales taxes applicable 

  
 -7- 

 
to the receipt of rent, personal property taxes imposed upon the fixtures, machinery, equipment, apparatus, systems and equipment, appurtenances, furniture and other personal property used in
connection with the Project), which Landlord shall pay during any Expense Year because of or in connection with the ownership, leasing and operation of the Project or Landlord’s interest therein. For purposes of this Lease, Tax Expenses shall
be calculated as if (i) the tenant improvements in the Building, the Other Future Building and any additional buildings added to the Project pursuant to Section 1.1.3 above (but only during the period of time that such Other Future
Building and additional buildings are included by Landlord within the Project) were fully constructed, and (ii) the Project, the Building, such Other Future Building and such additional buildings (if any) and all tenant improvements therein
were fully assessed for real estate tax purposes. 
 4.2.5.1 Tax Expenses shall include, without limitation: 

(i) Any tax on Landlord’s rent, right to rent or other income from the Project or as against Landlord’s business of leasing any of
the Project; 
 (ii) Any assessment, tax, fee, levy or charge in addition to, or in substitution, partially or totally, of any assessment,
tax, fee, levy or charge previously included within the definition of real property tax, it being acknowledged by Tenant and Landlord that Proposition 13 was adopted by the voters of the State of California in the June 1978 election
(“Proposition 13”) and that assessments, taxes, fees, levies and charges may be imposed by governmental agencies for such services as fire protection, street, sidewalk and road maintenance, refuse removal and for other governmental
services formerly provided without charge to property owners or occupants. It is the intention of Tenant and Landlord that all such new and increased assessments, taxes, fees, levies, and charges and all similar assessments, taxes, fees, levies and
charges be included within the definition of Tax Expenses for purposes of this Lease; 
 (iii) Any assessment, tax, fee, levy, or charge
allocable to or measured by the area of the Premises or the rent payable hereunder, including, without limitation, any gross income tax upon or with respect to the possession, leasing, operating, management, maintenance, alteration, repair, use or
occupancy by Tenant of the Premises, or any portion thereof; 
 (iv) Any assessment, tax, fee, levy or charge, upon this transaction or any
document to which Tenant is a party, creating or transferring an interest or an estate in the Premises; and 
 (v) Any reasonable expenses
incurred by Landlord in attempting to protest, reduce or minimize Tax Expenses. 
 4.2.5.2 Notwithstanding anything to the contrary
contained in this Section 4.2.5, there shall be excluded from Tax Expenses (i) all excess profits taxes, franchise taxes, gift taxes, capital stock taxes, inheritance and succession taxes, estate taxes, federal and state net income taxes,
and other taxes to the extent applicable to Landlord’s net income (as opposed to rents, receipts or income attributable to operations at the Project), (ii) any items included as Operating Expenses, (iii) any items paid by Tenant under
Section 4.4 below; and (iv) any assessments in excess of the amount which would be payable if such assessments were paid in installments over the longest permitted term. 

4.2.6 “Tenant’s Share” shall mean the percentage set forth in Section 9 of the Summary. Tenant’s Share was
calculated by dividing the number of rentable square feet of the Premises by the total rentable square feet in the Building (as set forth in Section 9 of the Summary), and stating such amount as a percentage. Landlord shall from time to time
redetermine the rentable square feet of the Premises and/or Building only if there is a change in the physical size thereof, and Tenant’s Share shall be appropriately adjusted to reflect any such redetermination. If Tenant’s Share is
adjusted pursuant to the foregoing, as to the Expense Year in which such adjustment occurs, Tenant’s Share for such year shall be determined on the basis of the number of days during such Expense Year that each such Tenant’s Share was in
effect. 

  
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 4.2.7 “Utilities Costs” shall mean all actual charges for utilities for the
Building and the Project (including utilities for the Other Future Building and additional buildings, if any, added to the Project during the period of time the same are included by Landlord within the Project) which Landlord shall pay during any
Expense Year, including, but not limited to, the costs of water, sewer, gas and electricity, and the costs of HVAC and other utilities, including any lab utilities and central plant utilities (but excluding those charges for which tenants directly
reimburse Landlord or otherwise pay directly to the utility company) as well as related fees, assessments, measurement meters and devices and surcharges. Utilities Costs shall be calculated assuming the Building (and, during the period of time when
such buildings are included by Landlord within the Project, the Other Future Building and any additional buildings, if any, added to the Project) are at least ninety-five percent (95%) occupied. If, during all or any part of any Expense Year,
Landlord shall not provide any utilities (the cost of which, if provided by Landlord, would be included in Utilities Costs) to a tenant (including Tenant) who has undertaken to provide the same instead of Landlord, Utilities Costs shall be deemed to
be increased by an amount equal to the additional Utilities Costs which would reasonably have been incurred during such period by Landlord if Landlord had at its own expense provided such utilities to such tenant. Utilities Costs shall include any
costs of utilities which are allocated to the Project under any declaration, restrictive covenant, or other instrument pertaining to the sharing of costs by the Project or any portion thereof, including any covenants, conditions or restrictions now
or hereafter recorded against or affecting the Project. Notwithstanding the foregoing, Utilities Costs shall not include: (A) any costs that would be considered a capital expenditure (with such costs treated, instead, as Operating Expenses, as
allowed under Section 4.2.3 above), (B) any connection fees, tap-in fees, or other fees for service to the Project not in existence as of the Commencement Date or (C) costs for services or utilities
not provided to Tenant under this Lease or of a nature that are payable directly by Tenant. 
 4.3 Calculation and Payment of Additional
Rent. 
 4.3.1 Payment of Operating Expenses, Tax Expenses and Utilities Costs. For each Expense Year ending or commencing within
the Lease Term, Tenant shall pay to Landlord, as Additional Rent, the following, which payment shall be made in the manner set forth in Section 4.3.2 below: (i) Tenant’s Share of Operating Expenses allocated to the Building pursuant
to Section 4.3.4 below; plus (ii) Tenant’s Share of Tax Expenses allocated to the Building pursuant to Section 4.3.4 below; plus (iii) Tenant’s Share of Utilities Costs allocated to the Building pursuant to
Section 4.3.4 below. 
 4.3.2 Statement of Actual Operating Expenses, Tax Expenses and Utilities Costs and Payment by Tenant.
Landlord shall endeavor to give to Tenant on or before the first (1st) day of June following the end of each Expense Year, a statement (the “Statement”) which shall state the Operating Expenses, Tax Expenses and Utilities Costs
incurred or accrued for such preceding Expense Year that are allocated to the Building pursuant to Section 4.3.4 below, and which shall indicate therein Tenant’s Share thereof. Within thirty (30) days after Tenant’s receipt of
the Statement for each Expense Year ending during the Lease Term, Tenant shall pay to Landlord the full amount of the Tenant’s Share of Operating Expenses, Tax Expenses and Utilities Costs for such Expense Year, less the amounts, if any, paid
during such Expense Year as the Estimated Expenses as defined in and pursuant to Section 4.3.3 below. If any Statement reflects that Tenant has overpaid Tenant’s Share of Operating Expenses and/or Tenant’s Share of Tax Expenses and/or
Tenant’s Share of Utilities Costs for such Expense Year, then Landlord shall, at Landlord’s option, either (i) remit such overpayment to Tenant within thirty (30) days after such applicable Statement is delivered to Tenant, or
(ii) credit such overpayment toward the Rent next due and payable by Tenant under this Lease. The failure of Landlord to timely furnish the Statement for any Expense Year shall not prejudice Landlord from enforcing its rights under this Article
4. Even though the Lease Term has expired and Tenant has vacated the Premises, if the Statement for the Expense Year in which this Lease terminates reflects that Tenant has overpaid and/or underpaid Tenant’s Share of the Operating Expenses
and/or Tenant’s Share of Tax Expenses and/or Tenant’s Share of Utilities Costs for such Expense Year, then within thirty (30) days after Landlord’s delivery of such Statement to Tenant, Landlord shall refund to Tenant any such
overpayment, or Tenant shall pay to Landlord any such underpayment, as the case may be. Tenant’s failure to object any Statement within one hundred twenty (120) days after Tenant’s receipt thereof shall constitute Tenant’s
irrevocable waiver to object to the same. The provisions of this Section 4.3.2 shall survive the expiration or earlier termination of the Lease Term. Notwithstanding the foregoing to the contrary, Tenant shall not be responsible for
Tenant’s Share of any Operating Expenses, Utilities Costs or Tax Expenses attributable to any calendar year which was first billed to Tenant more than twenty-four (24) months after the date (the “Cutoff Date”) which is the
earlier of (i) the expiration of the applicable calendar year or (i) the Lease Expiration Date, except that Tenant shall be responsible for Tenant’s Share of any Operating Expenses, Utilities Costs and Tax Expenses levied by any
governmental authority or by any public utility company at any time following the applicable Cutoff Date which are attributable to any calendar year occurring prior to such Cutoff Date, so long as Landlord delivers to tenant a bill and supplemental
statement for such amounts within ninety (90) days following Landlord’s receipt of the applicable bill therefor. 

  
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 4.3.3 Statement of Estimated Operating Expenses, Tax Expenses and Utilities Costs.
Landlord shall endeavor to give Tenant a yearly expense estimate statement (the “Estimate Statement”) which shall set forth Landlord’s reasonable estimate (the “Estimate”) of the total amount of Tenant’s
Share of the Operating Expenses, Tax Expenses and Utilities Costs allocated to the Building pursuant to Section 4.3.4 below for the then-current Expense Year shall be, and which shall indicate therein Tenant’s Share thereof (the
“Estimated Expenses”). The failure of Landlord to timely furnish the Estimate Statement for any Expense Year shall not preclude Landlord from enforcing its rights to collect any Estimated Expenses under this Article 4. Following
Landlord’s delivery of the Estimate Statement for the then-current Expense Year, Tenant shall pay, within thirty (30) days, a fraction of the Estimated Expenses for the then-current Expense Year (reduced by any amounts paid pursuant to the
last sentence of this Section 4.3.3). Such fraction shall have as its numerator the number of months which have elapsed in such current Expense Year to the month of such payment, both months inclusive, and shall have twelve (12) as its
denominator. Until a new Estimate Statement is furnished, Tenant shall pay monthly, with the monthly Base Rent installments, an amount equal to one-twelfth (1/12) of the total Estimated Expenses set forth in
the previous Estimate Statement delivered by Landlord to Tenant. 
 4.3.4 Allocation of Operating Expenses, Tax Expenses and Utilities
Costs to Building. The parties acknowledge that the Building is part of a multi-building commercial project consisting of the Building, and the Other Future Building and such other buildings as Landlord (and/or any other owners of the Project)
may elect to construct and include as part of the Project from time to time (the Other Future Building and any such other buildings are sometimes referred to herein, collectively, as the “Other Buildings”), and that certain of the
costs and expenses incurred in connection with the Project (i.e. the Operating Expenses, Tax Expenses and Utilities Costs) shall be shared among the Building and/or such Other Buildings (if any), while certain other costs and expenses which are
solely attributable to the Building and such Other Buildings, as applicable, shall be allocated directly to the Building and the Other Buildings, respectively. Accordingly, as set forth in Sections 4.1 and 4.2 above, Operating Expenses, Tax Expenses
and Utilities Costs are determined annually for the Project as a whole, and a portion of the Operating Expenses, Tax Expenses and Utilities Costs, which portion shall be determined by Landlord on an equitable basis, shall be allocated to the
Building (as opposed to the tenants of the Other Buildings), and such portion so allocated shall be the amount of Operating Expenses, Tax Expenses and Utilities Costs payable with respect to the Building upon which Tenant’s Share shall be
calculated. Such portion of the Operating Expenses, Tax Expenses and Utilities Costs allocated to the Building shall include all Operating Expenses, Tax Expenses and Utilities Costs which are attributable solely to the Building, and an equitable
portion of the Operating Expenses, Tax Expenses and Utilities Costs attributable to the Project as a whole and shall not include Operating Expenses, Tax Expenses and Utilities Costs related solely to the Other Buildings. As an example of such
allocation with respect to Tax Expenses and Utilities Costs, it is anticipated that Landlord (and/or any other owners of the Project) may receive separate tax bills which separately assess the improvements component of Tax Expenses for each building
in the Project and/or Landlord may receive separate utilities bills from the utilities companies identifying the Utilities Costs for certain of the utilities costs directly incurred by each such building (as measured by separate meters installed for
each such building), and such separately assessed Tax Expenses and separately metered Utilities Costs shall be calculated for and allocated separately to each such applicable building. In addition, in the event Landlord (and/or any other owners of
the Project) elect to subdivide certain common area portions of the Project such as landscaping, public and private streets, driveways, walkways, courtyards, plazas, transportation facilitation areas and/or accessways into a separate parcel or
parcels of land (and/or separately convey all or any of such parcels to a common area association to own, operate and/or maintain same), the Operating Expenses, Tax Expenses and Utilities Costs for such common area parcels of land may be aggregated
and then reasonably allocated by Landlord to the Building and such Other Buildings on an equitable basis as Landlord (and/or any applicable covenants, conditions and restrictions for any such common area association) shall provide from time to time.

 4.4 Taxes and Other Charges for Which Tenant Is Directly Responsible. Tenant shall reimburse Landlord upon demand for all taxes or
assessments required to be paid by Landlord (except to the extent included in Tax Expenses by Landlord), excluding state, local and federal personal or corporate income taxes measured by the net income of Landlord from all sources and estate and
inheritance taxes, whether or not now customary or within the contemplation of the parties hereto, when: 
 4.4.1 said taxes are measured by
or reasonably attributable to the cost or value of Tenant’s equipment, furniture, fixtures and other personal property located in the Premises; 

  
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 4.4.2 said taxes are assessed upon or due to the possession, leasing, operation, management,
maintenance, alteration, repair, use or occupancy by Tenant of the Premises or any portion of the Project; or 
 4.4.3 said taxes are
assessed upon this transaction or any document to which Tenant is a party creating or transferring an interest or an estate in the Premises. 

4.5 Late Charges. If any installment of Rent or any other sum due from Tenant shall not be received by Landlord or Landlord’s
designee within five (5) days of the due date therefor, then Tenant shall pay to Landlord a late charge equal to five percent (5%) of the amount due plus any attorneys’ fees incurred by Landlord by reason of Tenant’s failure to pay
Rent and/or other charges when due hereunder. The late charge shall be deemed Additional Rent and the right to require it shall be in addition to all of Landlord’s other rights and remedies hereunder, at law and/or in equity and shall not be
construed as liquidated damages or as limiting Landlord’s remedies in any manner. In addition to the late charge described above, any Rent or other amounts owing hereunder which are not paid by the date that they are due shall thereafter bear
interest until paid at a rate (the “Interest Rate”) equal to the lesser of (i) the “Prime Rate” or “Reference Rate” announced from time to time by the Bank of America (or such reasonable comparable national
banking institution as selected by Landlord in the event Bank of America ceases to exist or publish a Prime Rate or Reference Rate), plus four percent (4%), or (ii) the highest rate permitted by applicable law. Notwithstanding the foregoing,
before assessing a late charge or interest the first time in any one (1) year period, Landlord shall provide Tenant written notice of the delinquency, and shall waive such late charge if Tenant pays such delinquency within five (5) days
thereafter. 
 ARTICLE 5 

USE OF PREMISES; HAZARDOUS MATERIALS; ODORS AND EXHAUST 

5.1 Use. Tenant shall use the Premises solely for general office, laboratory, research and development, and all other uses to the
extent consistent with the current zoning for the Premises, all applicable laws and the first-class nature of the Project, and Tenant shall not use or permit the Premises to be used for any other purpose or purposes whatsoever, without
Landlord’s consent. Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use or purpose contrary to the provisions of Exhibit D, attached hereto, or in violation of the
laws of the United States of America, the state in which the Project is located, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project. Tenant
shall comply with the Rules and Regulations and all recorded covenants, conditions, and restrictions, and the provisions of all ground or underlying leases, now or hereafter affecting the Project, including but not limited to, (i) that certain
Declaration of Reciprocal Easements, Covenants and Restrictions of Centennial Towers, dated as of May 5, 2008, and recorded in the Official Records of San Mateo County, California (“Official Records”) on September 18, 2008
as Instrument No. 2008-105136, and (ii) that certain Declaration of Covenants, Conditions and Restrictions of Centennial Towers, dated March 27, 2009 and recorded in the Official Records on April 3, 2009, as Instrument
No. 2009-038658, as amended by that certain First Amendment to Declaration of Covenants, Conditions and Restrictions of Centennial Towers, dated as of April 20, 2010, and recorded in the Official Records on May 12, 2010, as Instrument
No. 2010-051876 (collectively, the “CC&Rs”), as the same may be amended, amended and restated, supplemented or otherwise modified from time to time; provided that any such amendments, restatements, supplements or
modifications do not materially modify Tenant’s rights or obligations hereunder. 
 5.2 Hazardous Materials. 

5.2.1 Definitions: As used in this Lease, the following terms have the following meanings: 

(a) “Environmental Law” means any past, present or future federal, state or local statutory or common law, or any regulation,
ordinance, code, plan, order, permit, grant, franchise, concession, restriction or agreement issued, entered, promulgated or approved thereunder, relating to (a) the environment, human health or safety, including, without limitation, emissions,
discharges, releases or threatened releases of Hazardous Materials (as defined below) into the environment (including, without limitation, air, surface water, groundwater or land), or (b) the manufacture, generation, refining, processing,
distribution, use, sale, treatment, receipt, storage, disposal, transport, arranging for transport, or handling of Hazardous Materials. 

  
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 (b) “Environmental Permits” mean collectively, any and all permits,
consents, licenses, approvals and registrations of any nature at any time required pursuant to, or in order to comply with, any Environmental Law including, but not limited to, any Spill Control Countermeasure Plan and any Hazardous Materials
Management Plan. 
 (c) “Hazardous Materials” shall mean and include any hazardous or toxic materials, substances or wastes
as now or hereafter designated or regulated under any Environmental Law, including, without limitation, asbestos, petroleum, petroleum hydrocarbons and petroleum based products, urea formaldehyde foam insulation, polychlorinated biphenyls
(“PCBs”), freon and other chlorofluorocarbons, “biohazardous waste,” “medical waste,” “infectious agent”, “mixed waste” or other waste under California Health and Safety Code §§ 117600 et,
seq. 
 (d) “Release” shall mean with respect to any Hazardous Materials, any release, deposit, discharge, emission,
leaking, pumping, leaching, spilling, seeping, migrating, injecting, pumping, pouring, emptying, escaping, dumping, disposing or other movement of Hazardous Materials in violation of Environmental Law or this Lease. 

5.2.2 Tenant’s Obligations – Environmental Permits. Tenant will (i) obtain and maintain in full force and effect all
Environmental Permits that may be required from time to time under any Environmental Laws applicable to Tenant or the Premises and (ii) be and remain in compliance with all terms and conditions of all such Environmental Permits and with all
other limitations, restrictions, conditions, standards, prohibitions, requirements, obligations, schedules and timetables contained in all Environmental Laws applicable to Tenant or the Premises. 

5.2.3 Tenant’s Obligations – Hazardous Materials. Except as expressly permitted herein, Tenant agrees not to cause or permit
any Hazardous Materials to be brought upon, stored, used, handled, generated, released or disposed of on, in, under or about the Premises, or any other portion of the Property by Tenant or its agents, employees, subtenants, assignees, licensees,
contractors or invitees (collectively, “Tenant’s Parties”), without the prior written consent of Landlord, which consent Landlord may withhold in its reasonable discretion. Landlord acknowledges that it is not the intent of
this Section 5.2 to prohibit Tenant from operating its business for the uses permitted hereunder, and Landlord hereby consents to Tenant’s storage, use, generation or release in compliance with applicable Environmental Laws of those
Hazardous Materials that are on the Hazardous Materials List. Tenant may operate its business according to the custom of Tenant’s industry so long as the use or presence of Hazardous Materials is strictly and properly monitored in accordance
with applicable Environmental Laws. As a material inducement to Landlord to allow Tenant to use Hazardous Materials in connection with its business, Tenant agrees to deliver to Landlord prior to the Lease Commencement Date a list identifying each
type of Hazardous Material to be present at the Premises and setting forth any and all governmental approvals or permits required in connection with the presence of such Hazardous Material at the Premises (the “Hazardous Materials
List”). Tenant shall deliver to Landlord an updated Hazardous Materials List on or prior to each annual anniversary of the Lease Commencement Date and shall also deliver an updated Hazardous Materials List before any new Hazardous Materials
are brought to the Premises. Tenant shall deliver to Landlord true and correct copies of the following documents (hereinafter referred to as the “Documents”) relating to the handling, storage, disposal and emission of Hazardous
Materials prior to the Lease Commencement Date or, if unavailable at that time, concurrently with the receipt from or submission to any Governmental Authority: permits; approvals; reports and correspondence; storage and management plans; notices of
violations of applicable Environmental Laws; plans relating to the installation of any storage tanks to be installed in, on, under or about the Premises (provided that installation of storage tanks shall only be permitted after Landlord has given
Tenant its written consent to do so, which consent Landlord may withhold in its sole and absolute (but good faith) discretion); and all closure plans or any other documents required by any and all governmental authorities for any storage tanks
installed in, on, under or about the Premises for the closure of any such storage tanks. For each type of Hazardous Material listed, the Documents shall include (t) the chemical name, (u) the material state (e.g., solid, liquid, gas or
cryogen), (v) the concentration, (w) the storage amount and storage condition (e.g., in cabinets or not in cabinets), (x) the use amount and use condition (e.g., open use or closed use), (y) the location (e.g., room number or other
identification) and (z) if known, the chemical abstract service number. Tenant shall not be required, however, to provide Landlord with any portion of the Documents containing information of a proprietary nature, which

  
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Documents, in and of themselves, do not contain a reference to any Hazardous Materials or activities related to Hazardous Materials. Upon the expiration or earlier termination of this Lease,
Tenant agrees to promptly remove from the Premises, the Building and the Project, at its sole cost and expense, any and all Hazardous Materials, including any equipment or systems containing Hazardous Materials which are installed, brought upon,
stored, used, generated or released (to the extent clean-up of any release is required by Environmental Laws) upon, in, under or about the Premises, the Building and/or the Project or any portion thereof by
Tenant or any of Tenant’s Parties during the Term of this Lease. 
 5.2.4 Landlord’s Right to Conduct Environmental
Assessment. At any time during the Lease Term, Landlord shall have the right to conduct an environmental assessment of the Premises (as well as any other areas in, on or about the Project that Landlord reasonably believes may have been affected
adversely by Tenant’s use of the Premises (collectively, the “Affected Areas”) in order to confirm that the Premises and the Affected Areas do not contain any Hazardous Materials in violation of applicable Environmental Laws or
under conditions constituting or likely to constitute a Release of Hazardous Materials. Such environmental assessment shall be a so-called “Phase I” assessment or such other level of investigation
which shall be the standard of diligence in the purchase or lease of similar property at the time, together with any additional investigation and report which would customarily follow any discovery contained in such initial Phase I assessment
(including, but not limited to, any so-called “Phase II” report). Such right to conduct such environmental assessment shall not be exercised more than once per calendar year unless Tenant is in
default under this Section 5.2. Such environmental assessments or inspections shall be subject to Article 22 and be at Landlord’s sole cost and expense unless it is discovered that Tenant has violated the terms of this Lease pertaining to
Hazardous Materials. 
 5.2.5 Tenant’s Obligations to perform Corrective Action. If the data from any environmental assessment
authorized and undertaken by Landlord pursuant to Section 5.2.4 indicates there has been a Release, threatened Release or other conditions with respect to Hazardous Materials on, under or emanating from the Premises and the Affected Areas by
Tenant or Tenant’s Parties that may require any investigation and/or active response action, including without limitation active or passive remediation and monitoring or any combination of these activities (“Corrective
Action”), Tenant shall immediately undertake Corrective Action with respect to such contamination if, and to the extent, required by the governmental authority exercising jurisdiction over the matter. Any Corrective Action performed by
Tenant will be performed with Landlord’s prior written approval and in accordance with applicable Environmental Laws, at Tenant’s sole cost and expense and by an environmental consulting firm (reasonably acceptable to Landlord). Tenant may
perform the Corrective Action before or after the expiration or earlier termination of this Lease, to the extent permitted by governmental agencies with jurisdiction over the Premises, the Building and the Project (provided, however, that any
Corrective Action performed after the expiration or earlier termination of this Lease shall be subject to the access fee provisions set forth below). If Tenant undertakes or continues Corrective Action after the expiration or earlier termination of
this Lease, Landlord, upon being given forty-eight (48) hours’ advance notice, may, in Landlord’s sole discretion, elect (without limiting any of the Landlord’s other rights and remedies under this Lease, at law and/or in
equity), to provide, at an “access fee” equal to one hundred fifty percent (150%) of the Monthly Rent in effect for the last month immediately preceding the expiration or earlier termination of this Lease, plus all other sums due under
this Lease (prorated for partial months based on days of actual access and only if the Premises cannot be used by a third party during such period), access to the Premises, the Building and the Project as may be requested by Tenant and its
consultant to accomplish the Corrective Action. Tenant or its consultant may install, inspect, maintain, replace and operate remediation equipment and conduct the Corrective Action as it considers necessary, subject to Landlord’s approval.
Tenant and Landlord shall, in good faith, cooperate with each other with respect to any Corrective Action after the expiration or earlier termination of this Lease so as not to interfere unreasonably with the conduct of Landlord’s or any third
party’s business on the Premises, the Building and the Project. Landlord may, in its sole discretion, provide access until Tenant delivers evidence reasonably satisfactory to Landlord that Tenant’s Corrective Action activities on the
Premises and the Affected Areas satisfy applicable Environmental Laws. It shall be reasonable for Landlord to require Tenant to deliver a “no further action” letter or substantially similar document from the applicable governmental agency.
Tenant shall pay the access fee for each day that Landlord is not able to use the Premises and the Affected Areas for such purposes as Landlord reasonably desires. Landlord’s “reasonableness” as used in the immediately preceding
sentence shall be based on (i) the zoning of the Premises as of the date in question, and (ii) the logical uses of the Premises as of the date in question. If Landlord desires to situate a tenant in the Premises, the Building or the
Project and is unable to do so due to the presence of Hazardous Materials in violation of Environmental Laws and caused by Tenant or Tenant Parties, and remediation of the Premises and the Affected Areas is ongoing, Landlord shall be deemed to be
unable to use the 

  
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Premises, the Building and the Project in the way Landlord reasonably desires and Tenant shall be obligated to continue paying the access fee until such time as Landlord is able to situate said
tenant in the Premises, the Building and/or the Project. Tenant agrees to install, at Tenant’s sole cost and expense, screening around its remediation equipment so as to protect the aesthetic appeal of the Premises, the Building and the
Project. Tenant also agrees to use reasonable efforts to locate its remediation and/or monitoring equipment, if any (subject to the requirements of Tenant’s consultant and governmental agencies with jurisdiction over the Premises, the Building
and the Project) in a location which will allow Landlord, to the extent reasonably practicable, the ability to lease the Premises, the Building and the Project to a subsequent user. Notwithstanding anything above to the contrary, if any clean-up or monitoring procedure is required by any applicable governmental authorities in, on, under or about the Premises and the Affected Areas during the Lease Term as a consequence of any Hazardous Materials
contamination caused by Tenant or Tenant’s Parties and the procedure for clean-up is not completed (to the satisfaction of Landlord and/or the governmental authorities) prior to the expiration or earlier
termination of this Lease then, at Landlord’s election, (i) this Lease shall be deemed renewed for a term commencing on the expiration or earlier termination of this Lease and ending on the date the
clean-up procedure is anticipated to be completed; or (ii) Tenant shall be deemed to have impermissibly held over (and Article 16 of this Lease shall apply with full force and effect) and Landlord shall
be entitled to all damages directly or indirectly incurred, including, without limitation, damages occasioned by the inability to relet the Premises and/or any other portion of the Building or a reduction of the fair market or rental value of the
Premises and/or the Building. 
 5.2.6 Tenant’s Duty to Notify Landlord Regarding Releases. Tenant agrees to promptly notify
Landlord of any Release of Hazardous Materials in the Premises, the Building or any other portion of the Project which Tenant becomes aware of during the Term of this Lease, whether caused by Tenant or any other persons or entities. In the event of
any release of Hazardous Materials caused by Tenant or any of Tenant’s Parties, Landlord shall have the right, but not the obligation, to cause Tenant, at Tenant’s sole cost and expense, to immediately take all reasonable steps Landlord
deems necessary or appropriate to remediate such Release and prevent any similar future release as required by Environmental Law to the satisfaction of Landlord and Landlord’s mortgagee(s). Tenant will, upon the request of Landlord at any time
during which Landlord has reason to believe that Tenant is not in compliance with this Section 5.2 (and in any event no earlier than sixty (60) days and no later than thirty (30) days prior to the expiration of this Lease), cause to
be performed an environmental audit of the Premises at Tenant’s expense by an established environmental consulting firm reasonably acceptable to Landlord. In the event the audit provides that Corrective Action is required then Tenant shall
immediately perform the same at its sole cost and expense. 
 5.2.7 Tenant’s Environmental Indemnity. To the fullest extent
permitted by law, Tenant agrees to promptly indemnify, protect, defend and hold harmless Landlord and Landlord’s members, partners, subpartners, independent contractors, officers, directors, shareholders, employees, agents, successors and
assigns (collectively, “Landlord Parties”) from and against any and all claims, damages, judgments, suits, causes of action, losses, liabilities, penalties, fines, expenses and costs (including, without limitation, clean-up, removal, remediation and restoration costs, sums paid in settlement of claims, attorneys’ fees, consultant fees and expert fees and court costs) which arise or result from the Release of Hazardous
Materials on, in, under or about the Premises, the Building or any other portion of the Project and which are caused by Tenant or any of Tenant’s Parties during the Term of this Lease, including arising from or caused in whole or in part,
directly or indirectly, by (i) Tenant’s or other Tenant Party’s actual, proposed or threatened use, treatment, storage, transportation, holding, existence, disposition, manufacturing, control, management, abatement, removal, handling,
transfer, generation or Release (past, present or threatened) of Hazardous Materials to, in, on, under, about or from the Premises and the Affected Areas in violation of Environmental Laws or this Lease; (ii) any past, present or threatened non-compliance or violations of any Environmental Laws in connection with Tenant and/or Tenant’s particular use of the Premises and/or the Affected Areas; (iii) personal injury claims; (iv) the
payment of any environmental liens, or the disposition, recording, or filing or threatened disposition, recording or filing of any environmental lien encumbering or otherwise affecting the Premises and/or the Affected Areas; (v) diminution in
the value of the Premises and/or the Project; (vi) damages for the loss or restriction of use of the Premises and/or the Project, including prospective rent, lost profits and business opportunities; (vii) sums paid in settlement of claims;
(viii) reasonable attorneys’ fees, consulting fees and expert fees; (ix) the cost of any investigation of site conditions; and (x) the cost of any repair, clean-up or remediation ordered by
any governmental or quasi-governmental agency or body. Tenant’s obligations hereunder shall include, without limitation, and whether foreseeable or unforeseeable, all costs of any required or necessary repair, cleanup or detoxification or
decontamination of the Premises, the Building and/or the Project, or the preparation and implementation of any closure, remedial action or other required plans in connection therewith. For purposes of the indemnity provisions in this
Section 5.2, any acts of Tenant and/or Tenant’s Parties or others acting for or on behalf of Tenant (whether or not they are negligent, intentional, willful or unlawful) shall be strictly attributable to Tenant. The provisions of this
Section 5.2.7 will survive the expiration or earlier termination of this Lease. 

  
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 5.2.8 Limitations on Tenant’s Obligations. Notwithstanding anything to the
contrary contained in this Lease, Tenant shall have no liability in connection with any Hazardous Materials (i) in existence on the Premises, Building or Project prior to the Lease Commencement Date or brought onto the Premises, Building or
Project after the Lease Commencement Date by any third party other than a Tenant Party or (ii) which may migrate into the Premises through air, water or soil, through no fault of Tenant or any Tenant Party. 

5.2.9 Landlord’s Termination Option for Certain Environmental Problems. If Hazardous Materials are present at the Premises that are
required by Environmental Law to be remediated and Tenant is not responsible therefor pursuant to Section 5.2, Landlord may, at its option, either (i) remediate such Hazardous Materials, in which event this Lease shall continue in full
force and effect or (ii) if the estimated cost to remediate such Hazardous Materials exceeds Two Million Dollars ($2,000,000.00) (the “Threshold Amount”), give written notice to Tenant, within thirty (30) days after
receipt by Landlord of knowledge of the existence of such Hazardous Materials, of Landlord’s desire to terminate this Lease as of the date ninety (90) days following the date of such notice. In the event Landlord elects to not terminate
the Lease and Landlord commences remediation, Landlord shall provide Tenant with an equitable abatement of Rent to the extent such work materially interferes with Tenant’s conduct of its business in the Premises and Tenant does not occupy all
or any material portion of the Premises on account of such work. 
 5.2.10 Control Areas. Tenant shall be allowed to the control areas
depicted on the attached Exhibit E building code, for chemical use or storage. 
 5.3 Odors and Exhaust. Tenant
acknowledges that Landlord would not enter into this Lease with Tenant unless Tenant assured Landlord that under no circumstances will the Premises be damaged by any exhaust from Tenant’s operations. Landlord and Tenant therefore agree as
follows: 
 5.3.1 Tenant shall not cause or permit (or conduct any activities that would cause) any release of any odors or fumes of any kind
from the Premises in violation of Environmental Laws. 
 5.3.2 If the Building has a ventilation system that, in Landlord’s judgment, is
adequate, suitable, and appropriate to vent the Premises in a manner that does not release odors affecting any indoor or outdoor part of the Premises, Tenant shall vent the Premises through such system. If Landlord at any time determines that any
existing ventilation system is inadequate, or if no ventilation system exists, Tenant shall in compliance with applicable laws vent all fumes and odors from the Premises (and remove odors from Tenant’s exhaust stream) as Landlord reasonably
requires. The placement and configuration of all ventilation exhaust pipes, louvers and other equipment shall be subject to Landlord’s reasonable approval. Tenant acknowledges Landlord’s legitimate desire to maintain the Premises (indoor
and outdoor areas) in an odor-free manner, and Landlord may require Tenant to abate and remove all odors in a manner that goes beyond the requirements of applicable laws. 

5.3.3 Tenant shall, at Tenant’s sole cost and expense, provide odor eliminators and other devices (such as filters, air cleaners,
scrubbers and whatever other equipment may in Landlord’s judgment be necessary or appropriate from time to time) to completely remove, eliminate and abate any offensive odors, fumes or other substances in Tenant’s exhaust stream that, in
Landlord’s judgment, emanate from the Premises. Any work Tenant performs under this Section 5.3 shall constitute Alterations. 

5.3.4 Tenant’s responsibility to remove, eliminate and abate odors, fumes and exhaust shall continue throughout the Term. 

5.3.5 If Tenant fails to install satisfactory odor control equipment within ten (10) business days after Landlord’s demand made at
any time, then Landlord may, without limiting Landlord’s other rights and remedies, require Tenant to cease and suspend any operations in the Premises that, in Landlord’s determination, cause odors, fumes or exhaust. 

  
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 ARTICLE 6 

SERVICES AND UTILITIES 

6.1 Standard Tenant Services. Landlord shall provide the following services on all days during the Lease Term, unless otherwise stated
below. 
 6.1.1 Subject to reasonable changes implemented by Landlord and to all governmental rules, regulations and guidelines applicable
thereto, Landlord shall provide heating, ventilation and air conditioning (“HVAC”) to the office portions of the Premises for normal office use in the Premises from Monday through Friday, during the period from 8:00 a.m. to 6:00
p.m., except for the date of observation of New Year’s Day, Presidents’ Day, Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day and other locally or nationally recognized holidays as designated by Landlord
(collectively, the “Holidays”). Landlord shall provide HVAC to the lab portions of the Premises on a 24/7 basis. 
 6.1.2
Landlord shall provide adequate electrical wiring and facilities and power for the Premises. Landlord shall designate the electricity utility provider from time to time. 

6.1.3 Landlord shall provide nonexclusive automatic passenger elevator service at all times. 

6.1.4 Landlord shall provide water in the Common Areas and Premises for lavatory, drinking, laboratory and landscaping purposes. Such cost
shall be paid by Tenant as Additional Rent as provided in Article 4. 
 6.1.5 Landlord shall provide gas and sewer services and utilities to
the Premises and the Project and trash pick-up from the Project as are reasonable and customary for tenants engaged in tenant’s business at the Premises. 

6.2 Overstandard Tenant Use. Tenant shall not overload the Systems and Equipment serving the Building. If Tenant desires to use HVAC for
the office portions of the Premises during hours other than those for which Landlord is obligated to supply such utilities pursuant to the terms of Section 6.1 of this Lease, (i) Tenant shall give Landlord such prior notice, as Landlord
shall from time to time establish as appropriate, of Tenant’s desired use, (ii) Landlord shall supply such HVAC to Tenant at such hourly cost to Tenant as Landlord shall from time to time establish, and (iii) Tenant shall pay such
cost to Landlord within thirty (30) days after billing, as additional rent. The hourly after-hours HVAC cost shall be equal to (A) the actual cost incurred by Landlord to supply such after-hours HVAC on an hourly basis (but based on a one
(1) hour minimum provision of such after-hours HVAC, (B) increased wear and tear and depreciation of equipment to provide such after-hours HVAC, and (C) the pro rata maintenance costs related to such after-hours HVAC. 

6.3 Utilities. Tenant shall pay for all water (including the cost to service, repair and replace reverse osmosis, de-ionized and other treated water), gas, heat, light, power, telephone, internet service, cable television, other telecommunications and other utilities supplied to the Premises, together with any fees, surcharges
and taxes thereon. If any such utility is not separately metered or submetered to Tenant, Tenant shall pay Tenant’s Share of all charges of such utility jointly metered with other premises as Additional Rent (provided, however, if any occupants
of the Building are, in Landlord’s good faith business judgment, using a disproportionate amount of utilities, Landlord shall exclude such disproportionate use before calculating Tenant’s Share) or, in the alternative, Landlord may, at its
option, monitor the usage of such utilities by Tenant and charge Tenant with the cost of purchasing, installing and monitoring such metering equipment, which cost shall be paid by Landlord. To the extent that Tenant uses more than Tenant’s
Share of any utilities, then Tenant shall pay Landlord Tenant’s Share of Operating Expenses to reflect such excess. 
 6.4
Interruption of Use. Tenant agrees that Landlord shall not be liable for damages, by abatement of Rent or otherwise, for failure to furnish or delay in furnishing any service (including, but not limited to, any central plant or other lab
system, telephone and telecommunication services), or for any diminution in the quality or quantity thereof, when such failure or delay or diminution is occasioned, in whole or in part, by repairs, replacements, or improvements, by any strike,
lockout or other labor trouble, by inability to secure electricity, gas, water, or other fuel at the Building or Project after reasonable effort to do so, by any accident or casualty whatsoever, by act or default of

  
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Tenant or other parties, or by any other cause beyond Landlord’s reasonable control; and such failures or delays or diminution shall never be deemed to constitute an eviction or disturbance
of Tenant’s use and possession of the Premises or relieve Tenant from paying Rent or performing any of its obligations under this Lease. Furthermore, Landlord shall not be liable under any circumstances for a loss of, or injury to, property
(including scientific research and any intellectual property) or for injury to, or interference with, Tenant’s business, including, without limitation, loss of profits, however occurring, through or in connection with or incidental to a failure
to furnish any of the services or utilities as set forth in this Article 6. 
 6.5 Additional Services. Landlord shall also have the
right, but not the obligation, at Tenant’s request, to provide any additional services which may be required by Tenant, including, without limitation, locksmithing and additional repairs and maintenance, provided that Tenant shall pay to
Landlord within ten (10) days after billing and as Additional Rent hereunder, the sum of all costs to Landlord of such additional services plus a five percent (5%) administration fee. 

6.6 Janitorial Service. Landlord shall not be obligated to provide any janitorial services to the Premises or replace any light bulbs,
lamps, starters and ballasts for lighting fixtures within the Premises. Tenant shall be solely responsible, at Tenant’s sole cost and expense, for (i) performing all janitorial services, trash removal and other cleaning of the Premises,
and (ii) replacement of all light bulbs, lamps, starters and ballasts for lighting fixtures within the Premises, all as appropriate to maintain the Premises in a first-class manner consistent with the first-class nature of the Building and
Project. Such services to be provided by Tenant shall be performed by contractors and pursuant to service contracts approved by Landlord. Tenant shall deposit trash as reasonably required in the area designated by Landlord from time to time. All
trash containers must be covered and stored in a manner to prevent the emanation of odors into the Premises or the Project. Landlord shall have the right to inspect the Premises upon reasonable notice to Tenant and to require Tenant to provide
additional cleaning, if necessary. In the event Tenant shall fail to provide any of the services described in this Section 6.6 to be performed by Tenant within five (5) days after notice from Landlord, which notice shall not be required in
the event of an emergency, Landlord shall have the right to provide such services and any charge or cost incurred by Landlord in connection therewith shall be deemed Additional Rent due and payable by Tenant upon receipt by Tenant of a written
statement of cost from Landlord. 
 6.7 Energy Statements. For any utilities serving the Premises for which Tenant is billed directly
by such utility provider, Tenant agrees to furnish to Landlord (a) any invoices or statements for such utilities within thirty (30) days after Tenant’s receipt thereof, (b) within thirty (30) days after Landlord’s
request, any other utility usage information reasonably requested by Landlord, and (c) within thirty (30) days after each calendar year during the Term, an ENERGY STAR® Statement of
Performance (or similar comprehensive utility usage report if requested by Landlord) and any other information reasonably requested by Landlord for the immediately preceding year. Tenant shall retain records of utility usage at the Premises,
including invoices and statements from the utility provider, for at least sixty (60) months, or such other period of time as may be requested by Landlord. Tenant acknowledges that any utility information for the Premises may be shared with
third parties, including Landlord’s consultants and governmental authorities. In the event that Tenant fails to comply with this Section, Tenant hereby authorizes Landlord to collect utility usage information directly from the applicable
utility providers. 
 ARTICLE 7 

REPAIRS 
 7.1
Tenant’s Repairs. Subject to Landlord’s repair obligations in Sections 7.2 and 11.1 below, Tenant shall, at Tenant’s own expense, keep the Premises, including all improvements, fixtures and furnishings therein, in good order,
repair and condition at all times during the Lease Term, which repair obligations shall include, without limitation, the obligation to promptly and adequately repair all damage to the Premises and replace or repair all damaged or broken fixtures and
appurtenances, together with all portions of the HVAC, electrical, mechanical plumbing, life safety and lab systems from the point that such systems are located in and solely serves the Premises and all portions of all fume hoods and other exhaust
systems that are located in and exclusively serve the Premises (all such systems collectively being referred to as the “Premises Systems”), in good condition. Tenant’s obligations shall include restorations, replacements or
renewals, including capital expenditures for restorations, replacements or renewals which will have an expected life beyond the Term, when necessary to keep the Premises and all improvements thereon or a part thereof and the Premises Systems in the
order, condition and repair and in compliance 

  
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with all applicable laws. Except as expressly set forth in this Lease, it is intended by the parties hereto that Landlord shall have no obligation, in any manner whatsoever, to repair or maintain
the Premises, the improvements located therein or the equipment therein, or the Premises Systems, all of which obligations are intended to be the expense of Tenant (whether or not such repairs, maintenance or restoration shall have an expected life
extending beyond the Term). Tenant’s maintenance of the Premises Systems shall comply with the manufacturers’ recommended operating and maintenance procedures. Tenant shall enter into and pay for maintenance contracts (in forms
satisfactory to Landlord in its sole reasonable discretion, which may require, without limitation, that any third party contractor provide Landlord with evidence of insurance as required by Landlord) for the Premises Systems in accordance with the
manufacturers’ recommended operating and maintenance procedures. Such maintenance contracts shall be with reputable contractors, satisfactory to Landlord in its sole reasonable discretion, who shall have not less than ten (10) years of
experience in maintaining such systems in biotechnical facilities. Upon Landlord’s request, Tenant shall provide maintenance reports from any such contractors. Tenant shall be solely responsible for the cost of all improvements or alterations
to the Premises or the Premises Systems required by law to the extent required under Article 21. Notwithstanding the foregoing, if Tenant fails to make such repairs, Landlord may, but need not, make such repairs and replacements, and Tenant shall
pay Landlord the cost thereof, including a percentage of the cost thereof (to be uniformly established for the Building) sufficient to reimburse Landlord for all overhead, general conditions, fees and other costs or expenses arising from
Landlord’s involvement with such repairs and replacements forthwith upon being billed for same. In addition, Landlord reserves the right, upon notice to Tenant, to procure and maintain any or all of such service contracts, and if Landlord so
elects, Tenant shall reimburse Landlord, upon demand, for the costs thereof. 
 7.2 Landlord’s Repairs. Anything contained in
Section 7.1 above to the contrary notwithstanding, and subject to Articles 11 and 12 below, Landlord shall repair and maintain the structural portions of the Building, including the plumbing, HVAC and electrical systems serving the Building and
not located in and exclusively serving the Premises; provided, however, to the extent such maintenance and repairs are caused by the act, neglect, fault of or omission of any duty by Tenant, its agents, servants, employees or invitees, Tenant shall
pay to Landlord as Additional Rent, the reasonable cost of such maintenance and repairs. Moreover, Landlord shall perform and construct, and Tenant shall have no responsibility to perform or construct, any repair, maintenance or improvements
(a) necessitated by the acts of Landlord, (b) for which Landlord has a right of reimbursement from others, and (c) to any portion of the Building outside of the demising walls of the Premises, and the common areas of the Project.
Landlord shall not be liable for any failure to make any such repairs, or to perform any maintenance. There shall be no abatement of rent and no liability of Landlord by reason of any injury to or interference with Tenant’s business arising
from the making of any repairs, alterations or improvements in or to any portion of the Project, Building or the Premises or in or to fixtures, appurtenances and equipment therein. Tenant hereby waives and releases its right to make repairs at
Landlord’s expense under Sections 1941 and 1942 of the California Civil Code; or under any similar law, statute, or ordinance now or hereafter in effect. 

ARTICLE 8 

ADDITIONS AND ALTERATIONS 

8.1 Landlord’s Consent to Alterations. Tenant may not make any improvements, alterations, additions or changes to the Premises
(collectively, the “Alterations”) without first procuring the prior written consent of Landlord to such Alterations, which consent shall be requested by Tenant not less than thirty (30) days prior to the commencement thereof,
and which consent shall not be unreasonably withheld by Landlord; provided, however, Landlord may withhold its consent in its sole and absolute discretion with respect to any Alterations which may materially or adversely affect the structural
components of the Building or the Systems and Equipment or which can be seen from outside the Premises (“Prohibited Alterations”). Notwithstanding the foregoing to the contrary, prior consent shall not be required with respect to
any interior Alterations to the premises which (i) are not Prohibited Alterations, (ii) cost less than Thirty Thousand Dollars ($30,000.00) for any one (1) job, and (iii) to not require a permit of any kind, as long as
(A) Tenant delivers to Landlord notice and a copy of any final plans, specifications and working drawings for any such Alterations at least ten (10) days prior to commencement of the work thereof, and (B) the other conditions of this
Article 8 are satisfied including, without limitation, conforming to Landlord’s rules, regulations and insurance requirements which govern contractors. Tenant shall pay for all overhead, general conditions, fees and other costs and expenses of
the Alterations, and shall pay to Landlord a Landlord supervision fee of two percent (2%) of the cost of the Alterations. The construction of the initial improvements to the Premises shall be governed by the terms of the Tenant Work Letter and not
the terms of this Article 8. 

  
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 8.2 Manner of Construction. Landlord may impose, as a condition of its consent to all
Alterations or repairs of the Premises, such requirements as Landlord in its reasonable discretion may deem desirable, including, but not limited to, the requirement that Tenant utilize for such purposes only contractors, materials, mechanics and
materialmen approved by Landlord; provided, however, Landlord may impose such requirements as Landlord may determine, in its sole and absolute discretion, with respect to any work materially or adversely affecting the structural components of the
Building or Systems and Equipment (including designating specific contractors to perform such work). Tenant shall construct such Alterations and perform such repairs in compliance with any and all applicable rules and regulations of any federal,
state, county or municipal code or ordinance and pursuant to a valid building permit, issued by the city in which the Building is located, and in conformance with Landlord’s construction rules and regulations. Landlord’s approval of the
plans, specifications and working drawings for Tenant’s Alterations shall create no responsibility or liability on the part of Landlord for their completeness, design sufficiency, or compliance with all laws, rules and regulations of
governmental agencies or authorities. All work with respect to any Alterations must be done in a good and workmanlike manner and diligently prosecuted to completion to the end that the Premises shall at all times be a complete unit except during the
period of work. Tenant shall cause all Alterations to be performed in such manner as not to obstruct access by any person to the Building or Project or the common areas, and as not to obstruct the business of Landlord or other tenants of the
Project, or interfere with the labor force working at the Project. If Tenant makes any Alterations, Tenant agrees to carry “Builder’s All Risk” insurance in an amount approved by Landlord covering the construction of such Alterations,
and such other insurance as Landlord may require, it being understood and agreed that all of such Alterations shall be insured by Tenant pursuant to Article 10 below immediately upon completion thereof. Landlord may, in its discretion, require
Tenant to obtain a lien and completion bond or some alternate form of security satisfactory to Landlord in an amount sufficient to ensure the lien-free completion of such Alterations (the estimated cost of which exceeds Two Hundred Fifty Thousand
Dollars ($250,000.00)) and naming Landlord as a co-obligee. Upon completion of any Alterations, Tenant shall (i) cause a Notice of Completion to be recorded in the office of the Recorder of the county in
which the Project is located in accordance with Section 3093 of the Civil Code of the State of California or any successor statute, (ii) deliver to the management office of the Building a reproducible copy of the “as built”
drawings of the Alterations, and (iii) deliver to Landlord evidence of payment, contractors’ affidavits and full and final waivers of all liens for labor, services or materials. 

8.3 Landlord’s Property. All Alterations, improvements, fixtures and/or equipment which may be installed or placed in or about the
Premises (including, but not limited to, all floor and wall coverings, built-in cabinet work and paneling, sinks and related plumbing fixtures, laboratory benches, exterior venting fume hoods and walk-in freezers and refrigerators, ductwork, conduits, electrical panels and circuits), shall be at the sole cost of Tenant and shall be and become the property of Landlord excluding Tenant’s fixtures and
equipment, including portable benches (other than ilab benches installed by Landlord as part of the Tenant Improvements which shall remain Landlord’s property), autoclaves, glasswashes, freezers, refrigerators, portable fume hoods, and
biosafety cabinets. Furthermore, Landlord may require that Tenant remove any Alterations, improvements, fixtures and/or equipment (other than the Tenant Improvements) upon the expiration or early termination of the Lease Term, and repair any damage
to the Premises and Building caused by such removal; provided that Landlord notifies in writing that such removal will be required at the time Landlord provides its consent to such Alterations, improvements, fixtures and/or equipment (or at the time
Tenant notifies Landlord with respect to Alterations not requiring Landlord’s consent). If Tenant fails to complete such removal and/or to repair by the end of the Lease Term, Landlord may do so and may charge the cost thereof to Tenant.
Notwithstanding any other provision of this Article 8 to the contrary, in no event shall Tenant remove any improvement from the Premises as to which Landlord contributed payment, including the Tenant Improvements, without Landlord’s prior
written consent, which consent Landlord may withhold in its sole and absolute discretion. 
 8.4
Wi-Fi Network. Without limiting the generality of the foregoing, if Tenant desires to install wireless intranet, Internet and communications network
(“Wi-Fi Network”) in the Premises for the use by Tenant and its employees, then the same shall be subject to the provisions of this Section 8.4 (in addition to the other provisions of
this Article 8). In the event Landlord consents to Tenant’s installation of such Wi-Fi Network, Tenant shall, in accordance with Article 15 below, remove the Wi-Fi
Network from the Premises prior to the termination of the Lease. Tenant shall use the Wi-Fi Network so as not to cause any interference to other tenants in the Building or to other

  
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tenants at the Project or with any other tenant’s communication equipment, and not to damage the Building or Project or interfere with the normal operation of the Building or Project, and
Tenant hereby agrees to indemnify, defend and hold Landlord harmless from and against any and all claims, costs, damages, expenses and liabilities (including attorneys’ fees) arising out of Tenant’s failure to comply with the provisions of
this Section 8.4, except to the extent same is caused by the negligence or willful misconduct of Landlord or Landlord’s breach of this Lease. Should any interference occur, Tenant shall take all necessary steps as soon as reasonably
possible and no later than three (3) calendar days following such occurrence to correct such interference. If such interference continues after such three (3) day period, Tenant shall immediately cease operating such Wi-Fi Network until such interference is corrected or remedied to Landlord’s satisfaction. Tenant acknowledges that Landlord has granted and/or may grant telecommunication rights to other tenants and occupants
of the Building and Project and to telecommunication service providers and in no event shall Landlord be liable to Tenant for any interference of the same with such Wi-Fi Network. Landlord makes no
representation that the Wi-Fi Network will be able to receive or transmit communication signals without interference or disturbance. Tenant shall (i) be solely responsible for any damage caused as a
result of the Wi-Fi Network, (ii) promptly pay any tax, license or permit fees charged pursuant to any laws or regulations in connection with the installation, maintenance or use of the Wi-Fi Network and comply with all precautions and safeguards recommended by all governmental authorities, (iii) pay for all necessary repairs, replacements to or maintenance of the Wi-Fi Network, and (iv) be responsible for any modifications, additions or repairs to the Building or Project, including without limitation, Building or Project systems or infrastructure, which are required by
reason of the installation, operation or removal of Tenant’s Wi-Fi Network. Should Landlord be required to retain professionals to research any interference issues that may arise and confirm Tenant’s
compliance with the terms of this Section 8.4, Tenant shall reimburse Landlord for the costs incurred by Landlord in connection with Landlord’s retention of such professionals, the research of such interference issues and confirmation of
Tenant’s compliance with the terms of this Section 8.4 within twenty (20) days after the date Landlord submits to Tenant an invoice for such costs. This reimbursement obligation is in addition to, and not in lieu of, any rights or
remedies Landlord may have in the event of a breach or default by Tenant under this Lease. 
 ARTICLE 9 

COVENANT AGAINST LIENS 

Tenant has no authority or power to cause or permit any lien or encumbrance of any kind whatsoever, whether created by act of Tenant,
operation of law or otherwise, to attach to or be placed upon the Project, Building or Premises, and any and all liens and encumbrances created by Tenant shall attach to Tenant’s interest only. Landlord shall have the right at all times to post
and keep posted on the Premises any notice which it deems necessary for protection from such liens. Tenant shall not cause or permit any lien of mechanics or materialmen or others to be placed against the Project, the Building or the Premises with
respect to work or services claimed to have been performed for or materials claimed to have been furnished to Tenant or the Premises, and, in case of any such lien attaching or notice of any lien, Tenant shall cause it to be immediately released and
removed of record. If any such lien is not released and removed within ten (10) business days after notice of such lien is delivered by Landlord to Tenant, then Landlord may, at its option, take all action necessary to release and remove such
lien, without any duty to investigate the validity thereof, and all sums, costs and expenses, including reasonable attorneys’ fees and costs, incurred by Landlord in connection with such lien shall be deemed Additional Rent under this Lease and
shall immediately be due and payable by Tenant. In the event that Tenant leases or finances the acquisition of equipment, furnishings or other personal property of a removable nature utilized by Tenant in the operation of Tenant’s business,
Tenant warrants that any Uniform Commercial Code financing statement shall, upon its face or by exhibit thereto, indicate that such financing statement is applicable only to removable personal property of Tenant located within the Premises. In no
event shall the address of the Premises be furnished on a financing statement without qualifying language as to applicability of the lien only to removable personal property located in an identified suite leased by Tenant. Should any holder of a
financing statement record or place of record a financing statement that appears to constitute a lien against any interest of Landlord or against equipment that may be located other than within an identified suite leased by Tenant, Tenant shall,
within ten (10) days after Landlord’s request, cause Tenant’s lender to amend such financing statement and any other documents of record to clarify that any liens imposed thereby are not applicable to any interest of Landlord in the
Premises. 

  
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 ARTICLE 10 

INDEMNIFICATION AND INSURANCE 

10.1 Indemnification and Waiver. Tenant hereby assumes all risk of damage to property and injury to persons, in, on, or about the
Premises from any cause whatsoever and agrees that Landlord and the Landlord Parties shall not be liable for, and are hereby released from any responsibility for, any damage to property or injury to persons or resulting from the loss of use thereof,
which damage or injury is sustained by Tenant or by other persons claiming through Tenant other than that arising from the negligence or willful misconduct of Landlord or its agents, contractors, licensees or invitees or a violation of
Landlord’s obligations under this Lease. Tenant shall indemnify, defend, protect, and hold harmless the Landlord Parties from any and all loss, cost, damage, expense and liability (including without limitation court costs and reasonable
attorneys’ fees) incurred in connection with or arising from any cause in, on or about the Premises (including, without limitation, Tenant’s installation, placement and removal of Alterations, improvements, fixtures and/or equipment in, on
or about the Premises), and any acts, omissions or negligence of Tenant or of any person claiming by, through or under Tenant, or of the contractors, agents, servants, employees, licensees or invitees of Tenant or any such person, in, on or about
the Premises, the Building and Project; provided, however, that the terms of the foregoing indemnity shall not apply to the negligence, violation of this Lease or willful misconduct of Landlord. The provisions of this Section 10.1 shall survive
the expiration or sooner termination of this Lease. Notwithstanding anything in this Lease to the contrary, Landlord shall not be liable to Tenant for, and Tenant assumes all risk of, damage to personal property or scientific research or
intellectual property, including loss of records kept by Tenant within the Premises and damage or losses caused by fire, electrical malfunction, gas explosion or water damage of any type (including broken water lines, malfunctioning fire sprinkler
systems, malfunctioning lab systems including any malfunction of the central plant systems, roof leaks or stoppages of lines). Tenant further waives any claim for injury to Tenant’s business or loss of income relating to any such damage or
destruction of personal property as described above. 
 10.2 Tenant’s Compliance with Landlord’s Fire and Casualty
Insurance. Tenant shall, at Tenant’s expense, comply as to the Premises with all insurance company requirements pertaining to Tenant’s particular use of the Premises. If Tenant’s conduct or use of the Premises causes any increase
in the premium for such insurance policies, then Tenant shall reimburse Landlord for any such increase. Tenant, at Tenant’s expense, shall comply with all rules, orders, regulations or requirements of the American Insurance Association
(formerly the National Board of Fire Underwriters) and with any similar body to the extent Tenant would be required to comply with the same if they were legal requirements under Article 21. 

10.3 Tenant’s Insurance. Tenant shall maintain the following coverages in the following amounts (which liability insurance limits
may be met by umbrella coverage): 
 10.3.1 Commercial General Liability Insurance covering the insured against claims of bodily injury,
personal injury and property damage arising out of Tenant’s operations, assumed liabilities or use of the Premises, including a Broad Form Commercial General Liability endorsement covering the insuring provisions of this Lease and the
performance by Tenant of the indemnity agreements set forth in Section 10.1 above, (and with owned and non-owned automobile liability coverage, and liquor liability coverage if alcoholic beverages are
served on the Premises) for limits of liability not less than: 
  

			
	Bodily Injury and	  	$5,000,000 each occurrence
	Property Damage Liability	  	$6,000,000 annual aggregate
	Personal Injury Liability	  	$5,000,000 each occurrence
		  	$6,000,000 annual aggregate
		  	0% Insured’s participation

 10.3.2 Physical Damage Insurance covering (i) all furniture, trade fixtures, equipment, merchandise and
all other items of Tenant’s property on the Premises installed by, for, or at the expense of Tenant, and (ii) all other improvements, alterations and additions to the Premises made by Tenant, including any improvements, alterations or
additions installed at Tenant’s request above the ceiling of the Premises or below the floor of the Premises other than the Tenant Improvements. Such insurance shall be written on a “physical loss or damage” basis under a
“special form” policy, for the full replacement cost value new without deduction for depreciation of the covered items and in amounts that meet any co-insurance clauses of the policies of insurance
and shall include a vandalism and malicious mischief endorsement, sprinkler leakage coverage and earthquake sprinkler leakage coverage. 

  
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 10.3.3 Workers’ compensation insurance as required by law. 

10.3.4 Loss-of-income, business interruption and extra-expense
insurance in such amounts as will reimburse Tenant for direct and indirect loss of earnings attributable to all perils commonly insured against by prudent tenants or attributable to prevention of loss of access to the Premises or to the Building as
a result of such perils. 
 10.3.5 Tenant shall carry comprehensive automobile liability insurance having a combined single limit of not less
than Two Million Dollars ($2,000,000.00) per occurrence and insuring Tenant against liability for claims arising out of ownership, maintenance or use of any owned, hired or non-owned automobiles. 

10.3.6 Intentionally Omitted. 

10.3.7 Form of Policies. The minimum limits of policies of insurance required of Tenant under this Lease shall in no event limit the
liability of Tenant under this Lease. Such insurance shall: (i) name Landlord, and any other party it so specifies, as an additional insured; (ii) specifically cover the liability assumed by Tenant under this Lease, including, but not
limited to, Tenant’s obligations under Section 10.1 above; (iii) be issued by an insurance company having a rating of not less than A-VII in Best’s Insurance Guide or which is otherwise
acceptable to Landlord and licensed to do business in the state in which the Project is located; (iv) be primary insurance as to all claims thereunder and provide that any insurance carried by Landlord is excess and is non-contributing with any insurance requirement of Tenant; (v) to the extent consistent with industry custom and practice, provide that said insurance shall not be canceled or coverage changed unless thirty
(30) days’ prior written notice shall have been given to Landlord and any mortgagee or ground or underlying lessor of Landlord; (vi) contain a cross-liability endorsement or severability of interest clause acceptable to Landlord; and
(vii) with respect to the insurance required in Sections 10.3.1, 10.3.2 and 10.3.4 above, have deductible amounts not exceeding Twenty Thousand Dollars ($20,000.00). Tenant shall deliver such policies or certificates thereof to Landlord on or
before the Lease Commencement Date and at least thirty (30) days before the expiration dates thereof. If Tenant shall fail to procure such insurance, or to deliver such policies or certificate, within such time periods, Landlord may, at its
option, in addition to all of its other rights and remedies under this Lease, and without regard to any notice and cure periods set forth in Section 19.1, procure such policies for the account of Tenant, and the cost thereof shall be paid to
Landlord as Additional Rent within ten (10) days after delivery of bills therefor. Tenant shall have the right to carry the insurance required hereunder in the form of blanket and/or umbrella policies. 

10.4 Subrogation. Landlord and Tenant agree to have their respective insurance companies issuing property damage, workers’
compensation, public/general liability, insurance waive any rights of subrogation that such companies may have against Landlord or Tenant, as the case may be. Notwithstanding anything to the contrary in this Lease, Landlord and Tenant hereby waive
any right that either may have against the other on account of any loss or damage to their respective property to the extent such loss or damage is insurable under policies of insurance for fire and all risk coverage, theft, or other similar
insurance, without regard to the negligence or willful misconduct of the entity so released. All of Landlord’s and Tenant’s repair and indemnity obligations under this Lease shall be subject to the waiver contained in this paragraph. 

10.5 Additional Insurance Obligations. Tenant shall carry and maintain during the entire Lease Term, at Tenant’s sole cost and
expense, increased amounts of the insurance required to be carried by Tenant pursuant to this Article 10, and such other reasonable types of insurance coverage and in such reasonable amounts covering the Premises and Tenant’s operations
therein, as may be reasonably requested by Landlord so long as such amounts or types are then generally being required by landlords of similar buildings in the area. 

  
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 ARTICLE 11 

DAMAGE AND DESTRUCTION 

11.1 Repair of Damage to Premises by Landlord. Tenant shall promptly notify Landlord of any damage to the Premises resulting from fire
or any other casualty. If the Premises or any common areas of the Building or Project serving or providing access to the Premises shall be damaged by fire or other casualty, Landlord shall notify Tenant of the estimated date of completion of the
repair (“Estimated Repair Completion Date”). Landlord shall promptly and diligently, subject to reasonable delays for insurance adjustment or other matters beyond Landlord’s reasonable control, and subject to all other terms of
this Article 11, restore the Premises, including the Tenant Improvements and Landlord’s Work, and such common areas. Such restoration shall be to substantially the same condition of the base, shell, and core of the Premises, the Tenant
Improvements, Landlord’s Work and common areas prior to the casualty, except for modifications required by zoning and building codes and other laws or by the holder of a mortgage on the Project and/or the Building, or the lessor of a ground or
underlying lease with respect to the Building, or any other modifications to the common areas deemed desirable by Landlord, provided access to the Premises and any common restrooms serving the Premises shall not be materially impaired. Upon the
occurrence of any damage to the Premises, Tenant shall assign to Landlord (or to any party designated by Landlord) all insurance proceeds payable to Tenant under Tenant’s insurance required under Section 10.3 of this Lease attributable to
Alterations made by Tenant, and Landlord shall repair any damage to such Alterations installed in the Premises and shall return such alterations to their original condition; provided that if the costs of such repair of such Alterations by Landlord
exceeds the amount of insurance proceeds received by Landlord therefor from Tenant’s insurance carrier, as assigned by Tenant, the excess costs of such repairs shall be paid by Tenant to Landlord prior to Landlord’s repair of the damage.
In connection with such repairs and replacements of any such Alterations, Tenant shall, prior to Landlord’s commencement of such improvement work, submit to Landlord, for Landlord’s review and approval, all plans, specifications and
working drawings relating thereto, and Landlord shall select the contractors to perform such improvement work. Landlord shall not be liable for any inconvenience or annoyance to Tenant or its visitors, or injury to Tenant’s business resulting
in any way from such damage or the repair thereof; provided however, that if such fire or other casualty shall have damaged the Premises or common areas necessary to Tenant’s occupancy, Landlord shall allow Tenant a proportionate abatement of
Base Rent and Tenant’s Share of Operating Expenses, Tax Expenses and Utilities Costs during the time and to the extent the Premises are unusable by Tenant for its business purposes permitted under this Lease, and not occupied by Tenant as a
result thereof. 
 11.2 Landlord’s Option to Repair. Notwithstanding Section 11.1 above to the contrary, Landlord may elect
not to rebuild and/or restore the Premises, the Building and/or any other portion of the Project and instead terminate this Lease by notifying Tenant in writing of such termination within sixty (60) days after the date Landlord becomes aware of
such damage, such notice to include a termination date giving Tenant ninety (90) days to vacate the Premises, but Landlord may so elect only if the Building shall be damaged by fire or other casualty or cause, and the Premises are affected, and
one or more of the following conditions is present: (i) repairs cannot reasonably be substantially completed within one hundred eighty (180) days after the date of such damage (when such repairs are made without the payment of overtime or
other premiums); (ii) the holder of any mortgage on the Project and/or the Building or ground or underlying lessor with respect to the Project and/or the Building shall require that the insurance proceeds or any portion thereof be used to retire the
mortgage debt, or shall terminate the ground or underlying lease, as the case may be and Landlord elects to terminate the leases of all other tenants of the Building similarly affected by the damage and destruction; or (iii) the damage is not
fully covered, except for deductible amounts, by Landlord’s insurance policies and Landlord elects to terminate the leases of all other tenants of the Building similarly affected by the damage and destruction. In addition, if the Premises and
the Building is destroyed or damaged to any substantial extent during the last year of the Lease Term, then notwithstanding anything contained in this Article 11, Landlord shall have the option to terminate this Lease by giving written notice to
Tenant of the exercise of such option within thirty (30) days after such damage, in which event this Lease shall cease and terminate as of the date of such notice. Upon any such termination of this Lease pursuant to this Section 11.2,
Tenant shall pay the Base Rent and Additional Rent, properly apportioned up to such date of termination, and both parties hereto shall thereafter be discharged of all further obligations under this Lease, except for those obligations which expressly
survive the expiration or earlier termination of the Lease Term. 
 11.3 Waiver of Statutory Provisions. The provisions of this Lease,
including this Article 11, constitute an express agreement between Landlord and Tenant with respect to any and all damage to, or destruction of, all or any part of the Premises, the Building or any other portion of the Project, and any statute or
regulation of the state in which the Project is located, including, without limitation, Sections 1932(2) and 1933(4) of the California Civil Code, with respect to any rights or obligations concerning damage or destruction in the absence of an
express agreement between the parties, and any other statute or regulation, now or hereafter in effect, shall have no application to this Lease or any damage or destruction to all or any part of the Premises, the Building or any other portion of the
Project. 

  
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 11.4 Tenant’s Termination Rights Following Damage. Tenant, at any time after the
damage until such rebuilding is completed, may terminate this Lease by delivering written notice to Landlord of such termination, in which event this Lease shall terminate as of the date of the giving of such notice, in any of the following
circumstances: (i) Landlord fails to restore the Premises (including reasonable means of access thereto) within a period which is sixty (60) days longer than the Estimated Repair Completion Date stated in Landlord’s notice to Tenant
as the estimated rebuilding period (which sixty (60) day period shall be deemed extended due to Force Majeure delays and/or delays caused by Tenant); (ii) the Estimated Completion Repair Date is more than one hundred eighty (180) days
following the damage; or (iii) material damage occurs within the last year of the Term to the extent that in Tenant’s judgment it cannot effectively operate its business in the Premises. 

ARTICLE 12 

CONDEMNATION 
 12.1
Permanent Taking. If the whole or any substantial part of the Premises, Building or Project shall be taken by power of eminent domain or condemned by any competent authority for any public or quasi-public use or purpose, or if any adjacent
property or street shall be so taken or condemned, or reconfigured or vacated by such authority in such manner as to require the use, reconstruction or remodeling of any substantial part of the Premises, Building or Project, or if Landlord shall
grant a deed or other instrument in lieu of such taking by eminent domain or condemnation, Landlord shall have the option to terminate this Lease upon ninety (90) days’ notice, provided such notice is given no later than one hundred eighty
(180) days after the date of such taking, condemnation, deed or other instrument. If more than twenty-five percent (25%) of the rentable square feet of the Premises is taken, or if access to the Premises is substantially impaired, Tenant shall
have the option to terminate this Lease upon ninety (90) days’ notice, provided such notice is given no later than one hundred eighty (180) days after the date of such taking. Landlord shall be entitled to receive the entire award or
payment in connection therewith, except that Tenant shall have the right to file any separate claim available to Tenant for any taking of Tenant’s personal property and fixtures belonging to Tenant and removable by Tenant upon expiration of the
Lease Term pursuant to the terms of this Lease, and for relocation expenses, so long as such claim does not diminish the award available to Landlord, or its ground lessor or mortgagee with respect to the Project, and such claim is payable separately
to Tenant. All Rent shall be apportioned as of the date of such termination, or the date of such taking, whichever shall first occur. If any part of the Premises shall be taken, and this Lease shall not be so terminated, the Base Rent and
Tenant’s Share of Operating Expenses, Tax Expenses and Utilities Costs shall be proportionately abated. Tenant hereby waives any and all rights it might otherwise have pursuant to Section 1265.130 of The California Code of Civil Procedure.

 12.2 Temporary Taking. Notwithstanding anything to the contrary contained in this Article 12, in the event of a temporary taking of
all or any portion of the Premises for a period of one hundred and eighty (180) days or less, then this Lease shall not terminate but the Base Rent and Tenant’s Share of Operating Expenses, Tax Expenses and Utilities Costs shall be abated
for the period of such taking in proportion to the ratio that the amount of rentable square feet of the Premises taken bears to the total rentable square feet of the Premises. Landlord shall be entitled to receive the entire award made in connection
with any such temporary taking. 
 ARTICLE 13 

COVENANT OF QUIET ENJOYMENT 

Landlord covenants that Tenant, on paying the Rent, charges for services and other payments herein reserved and on keeping, observing and
performing all the other terms, covenants, conditions, and agreements herein contained on the part of Tenant to be kept, observed and performed, shall, during the Lease Term, peaceably and quietly have, hold and enjoy the Premises subject to the
terms, covenants, conditions, and agreements hereof without interference by any persons lawfully claiming by or through Landlord. The foregoing covenant is in lieu of any other covenant express or implied. 

  
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 ARTICLE 14 

ASSIGNMENT AND SUBLETTING 

14.1 Transfers. Tenant shall not, without the prior written consent of Landlord (not to be unreasonably withheld), assign, mortgage,
pledge, hypothecate, encumber, or permit any lien to attach to, or otherwise transfer, this Lease or any interest hereunder, permit any assignment or other such foregoing transfer of this Lease or any interest hereunder by operation of law, sublet
the Premises or any part thereof, or permit the use of the Premises by any persons other than Tenant and its employees and contractors (all of the foregoing are hereinafter sometimes referred to collectively as “Transfers” and any
person to whom any Transfer is made or sought to be made is hereinafter sometimes referred to as a “Transferee”). If Tenant shall desire Landlord’s consent to any Transfer, Tenant shall notify Landlord in writing, which notice
(the “Transfer Notice”) shall include (i) the proposed effective date of the Transfer, which shall not be less than thirty (30) days nor more than one hundred eighty (180) days after the date of delivery of the
Transfer Notice, (ii) a description of the portion of the Premises to be transferred (the “Subject Space”), (iii) all of the terms of the proposed Transfer, the name and address of the proposed Transferee, and a copy of all
existing and/or proposed documentation pertaining to the proposed Transfer, (iv) current financial statements of the proposed Transferee certified by an officer, partner or owner thereof, (v) a list of Hazardous Materials, certified by the
proposed Transferee to be true and correct, that the proposed Transferee intends to use or store in the Premises, and (vi) such other information as Landlord may reasonably require. Any Transfer made without Landlord’s prior written
consent shall, at Landlord’s option, be null, void and of no effect, and shall, at Landlord’s option, constitute a default by Tenant under this Lease after the expiration of applicable notice and cure periods. Whether or not Landlord shall
grant consent, within thirty (30) days after written request by Landlord, Tenant shall pay to Landlord up to Two Thousand Five Hundred Dollars ($2,500.00) to reimburse Landlord for its review and processing fees, and any legal fees incurred by
Landlord in connection with Tenant’s proposed Transfer. 
 14.2 Landlord’s Consent. Landlord shall not unreasonably withhold
its consent to any proposed Transfer on the terms specified in the Transfer Notice. In no event shall Landlord be deemed to be unreasonable for declining to consent to a Transfer to a transferee jeopardizing directly or indirectly the status of
Landlord or any of Landlord’s affiliates as a Real Estate Investment Trust under the Internal Revenue Code of 1986 (as the same may be amended from time to time, the “Revenue Code”). Notwithstanding anything contained in this
Lease to the contrary, (w) no Transfer shall be consummated on any basis such that the rental or other amounts to be paid by the occupant, assignee, manager or other transferee thereunder would be based, in whole or in part, on the income or
profits derived by the business activities of such occupant, assignee, manager or other transferee; (x) Tenant shall not consummate a Transfer with any person in which Landlord owns an interest, directly or indirectly (by applying constructive
ownership rules set forth in Section 856(d)(5) of the Revenue Code); and (y) Tenant shall not consummate a Transfer with any person or in any manner that could cause any portion of the amounts received by Landlord pursuant to this Lease or
any sublease, license or other arrangement for the right to use, occupy or possess any portion of the Premises to fail to qualify as “rents from real property” within the meaning of Section 856(d) of the Revenue Code, or any similar
or successor provision thereto or which could cause any other income of Landlord to fail to qualify as income described in Section 856(c)(2) of the Revenue Code. The parties hereby agree that it shall be reasonable under this Lease and under
any applicable law for Landlord to withhold consent to any proposed Transfer where one or more of the following apply, without limitation as to other reasonable grounds for withholding consent: 

14.2.1 The Transferee is of a character or reputation or engaged in a business which is not consistent with the quality of the Building or
Project; 
 14.2.2 The Transferee intends to use the Subject Space for purposes which are not permitted under this Lease; 

14.2.3 The Transferee is either a governmental agency or instrumentality thereof; 

14.2.4 The Transfer will result in more than a reasonable and safe number of occupants per floor within the Subject Space; 

14.2.5 The Transferee is not a party of reasonable financial worth and/or financial stability in light of the responsibilities involved under
the Lease or the applicable sublease on the date consent is requested; 

  
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 14.2.6 The proposed Transfer would cause Landlord to be in violation of another lease or
agreement to which Landlord is a party, or would give an occupant of the Project a right to cancel its lease; 
 14.2.7 The terms of the
proposed Transfer will allow the Transferee to exercise a right of renewal, right of expansion, right of first offer, or other similar right held by Tenant (or will allow the Transferee to occupy space leased by Tenant pursuant to any such right);
or 
 14.2.8 Either the proposed Transferee, or any person or entity which directly or indirectly, controls, is controlled by, or is under
common control with, the proposed Transferee, (i) occupies space in the Project at the time of the request for consent, (ii) is negotiating with Landlord to lease space in the Project at such time, or (iii) has negotiated with
Landlord during the one (1)-month period immediately preceding the Transfer Notice, in each case if Landlord then has suitable space available to such proposed Transferee. 

If Landlord consents to any Transfer pursuant to the terms of this Section 14.2 (and does not exercise any recapture rights Landlord may
have under Section 14.4 below), Tenant may within six (6) months after Landlord’s consent, enter into such Transfer of the Premises or portion thereof, upon substantially the same terms and conditions as are set forth in the Transfer
Notice furnished by Tenant to Landlord pursuant to Section 14.1 above, provided that if there are any changes in the terms and conditions from those specified in the Transfer Notice (i) such that Landlord would initially have been entitled
to refuse its consent to such Transfer under this Section 14.2, or (ii) which would cause the proposed Transfer to be more favorable to the Transferee than the terms set forth in Tenant’s original Transfer Notice, Tenant shall again
submit the Transfer to Landlord for its approval and other action under this Article 14 (including Landlord’s right of recapture, if any, under Section 14.4 of this Lease). 

14.3 Transfer Premium. If Landlord consents to a Transfer, as a condition thereto which the parties hereby agree is reasonable, Tenant
shall pay to Landlord fifty (50%) of any Transfer Premium received by Tenant from such Transferee. “Transfer Premium” shall mean all rent, additional rent or other consideration payable by such Transferee in excess of the Rent and
Additional Rent payable by Tenant under this Lease on a per rentable square foot basis if less than all of the Premises is transferred, after deducting the reasonable expenses incurred by Tenant for (i) any reasonable changes, alterations and
improvements to the Premises in connection with the Transfer (but only to the extent approved by Landlord), and (ii) any reasonable brokerage commissions and attorney’s fees in connection with the Transfer (collectively, the
“Subleasing Costs”). Transfer Premium shall also include, but not be limited to, key money and bonus money paid by Transferee to Tenant in connection with such Transfer, and any payment in excess of fair market value for services
rendered by Tenant to Transferee or for assets, fixtures, inventory, equipment, or furniture transferred by Tenant to Transferee in connection with such Transfer. 

14.4 Landlord’s Option as to Subject Space. Notwithstanding anything to the contrary contained in this Article 14, if Tenant
requests Landlord’s consent to Transfer substantially all of the Premises for substantially the remaining Term, Landlord shall have the option, by giving written notice to Tenant within thirty (30) days after receipt of any Transfer
Notice, to terminate this Lease. If Landlord declines, or fails to elect in a timely manner to terminate this Lease under this Section 14.4, then, provided Landlord has consented to the proposed Transfer, Tenant shall be entitled to proceed to
transfer the Subject Space to the proposed Transferee, subject to provisions of the last paragraph of Section 14.2 above. 
 14.5
Effect of Transfer. If Landlord consents to a Transfer: (i) the terms and conditions of this Lease shall in no way be deemed to have been waived or modified; (ii) such consent shall not be deemed consent to any further Transfer by
either Tenant or a Transferee; (iii) Tenant shall deliver to Landlord, promptly after execution, an original executed copy of all documentation pertaining to the Transfer in form reasonably acceptable to Landlord; and (iv) no Transfer
relating to this Lease or agreement entered into with respect thereto, whether with or without Landlord’s consent, shall relieve Tenant or any guarantor of the Lease from liability under this Lease. Landlord or its authorized representatives
shall have the right at all reasonable times to audit the books, records and papers of Tenant relating to any Transfer, and shall have the right to make copies thereof. If the Transfer Premium respecting any Transfer shall be found understated,
Tenant shall, within thirty (30) days after demand, pay the deficiency and Landlord’s costs of such audit. 

  
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 14.6 Additional Transfers. Subject to Section 14.7 below, for purposes of this
Lease, the term “Transfer” shall also include: (i) if Tenant is a partnership or limited liability company, the withdrawal or change, voluntary, involuntary or by operation of law, of more than fifty percent (50%) of the partners or
members, or transfer of more than fifty percent (50%) of the partnership or membership interests, within a twelve (12)-month period, or the dissolution of the partnership without immediate reconstitution thereof; and (ii) if Tenant is a closely
held corporation (i.e., whose stock is not publicly held and not traded through an exchange or over the counter), (A) the dissolution, merger, consolidation or other reorganization of Tenant, or (B) the sale or other transfer of more than an
aggregate of fifty percent (50%) of the voting shares of Tenant (other than to immediate family members by reason of gift or death), within a twelve (12)-month period. Notwithstanding the foregoing, the sale, issuance or transfer of Tenant’s
capital stock or membership interests pursuant to an equity financing or public offering shall not be deemed an assignment, subletting or any other Transfer of this Lease or the Premises. 

14.7 Affiliated Companies/Restructuring of Business Organization. The assignment or subletting by Tenant of all or any portion of this
Lease or the Premises to (i) a parent or subsidiary of Tenant, or (ii) any person or entity which controls, is controlled by or under common control with Tenant, or (iii) any entity which purchases all or substantially all of the
assets or stock of Tenant in one or a series of transactions, (iv) any entity into which Tenant is merged or consolidated, or (v) in connection with any deemed Transfer due to a transfer of shares or membership interests under
Section 14.6 above where Tenant remains the tenant under this Lease (all such persons or entities described in (i), (ii), (iii) and (iv) being sometimes hereinafter referred to as “Affiliates”) shall not be deemed a
Transfer under this Article 14, provided that: 
 14.7.1 Any such Affiliate was not formed as a subterfuge to avoid the obligations of this
Article 14; 
 14.7.2 Tenant gives Landlord prior written notice of any such assignment or sublease to an Affiliate; 

14.7.3 Any such Affiliate (or Tenant, if Tenant is to remain the tenant under this Lease) has, following the effective date of any such
assignment or sublease, a tangible net worth, in the aggregate, computed in accordance with generally accepted accounting principles, which is sufficient (in Landlord’s reasonable good faith opinion) to meet the obligations of Tenant under this
Lease or the applicable Transfer document; 
 14.7.4 Any such assignment or sublease, exclusive of such Transfer as may occur pursuant to
Section 14.6, shall be subject to all of the terms and provisions of this Lease, and such assignee or sublessee shall assume, in a written document reasonably satisfactory to Landlord and delivered to Landlord upon or prior to the effective
date of such assignment or sublease, all the obligations of Tenant under this Lease; and 
 14.7.5 Tenant shall remain fully liable for all
obligations to be performed by Tenant under this Lease. 
 An Affiliate that is an assignee of Original Tenant’s entire interest in
this Lease may be referred to as an “Affiliate Assignee.” 
 ARTICLE 15 

SURRENDER; OWNERSHIP AND REMOVAL OF PERSONAL PROPERTY 

15.1 Surrender of Premises. No act or thing done by Landlord or any agent or employee of Landlord during the Lease Term shall be deemed
to constitute an acceptance by Landlord of a surrender of the Premises unless such intent is specifically acknowledged in a writing signed by Landlord. The delivery of keys to the Premises to Landlord or any agent or employee of Landlord shall not
constitute a surrender of the Premises or effect a termination of this Lease, whether or not the keys are thereafter retained by Landlord, and notwithstanding such delivery Tenant shall be entitled to the return of such keys at any reasonable time
upon request until this Lease shall have been properly terminated. The voluntary or other surrender of this Lease by Tenant, whether accepted by Landlord or not, or a mutual termination hereof, shall not work a merger, and at the option of Landlord
shall operate as an assignment to Landlord of all subleases or subtenancies affecting the Premises. 

  
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 15.2 Removal of Tenant Property by Tenant. Upon the expiration of the Lease Term, or
upon any earlier termination of this Lease, Tenant shall, subject to the provisions of this Article 15, quit and surrender possession of the Premises to Landlord in as good order and condition as when Tenant took possession and as thereafter
improved by Landlord and/or Tenant, reasonable wear and tear, casualties, alterations or other interior improvements which Tenant is permitted to surrender at the termination of this Lease and repairs which are not the responsibility of Tenant
hereunder excepted. Tenant’s restoration obligations may also include satisfying Landlord’s commercially reasonable procedures regarding the cleaning of any lab systems and sealing any connection points of any such lab systems to the
Premises, all at Tenant’s sole cost and expense. At least ten (10) days prior to Tenant’s surrender of possession of any part of the Premises, Tenant shall provide Landlord with (a) a facility decommissioning and Hazardous
Materials closure plan for the Premises (“Exit Survey”) prepared by an independent third party reasonably acceptable to Landlord, and (b) written evidence of all appropriate governmental releases obtained by Tenant in
accordance with applicable laws, including laws pertaining to the surrender of the Premises. In addition, Tenant agrees to remain responsible after the surrender of the Premises for the remediation of any recognized environmental conditions set
forth in the Exit Survey and caused by Tenant or any Tenant’s Parties and compliance with any recommendations set forth in the Exit Survey. Tenant shall, upon the expiration or earlier termination of this Lease, furnish to Landlord evidence
that Tenant has closed all governmental permits and licenses, if any, issued in connection with Tenant’s or Tenant’s Parties’ activities at the Premises. If any such governmental permits or licenses have been issued and Tenant fails
to provide evidence of such closure on or before the expiration or earlier termination of this Lease, then until Tenant does so, the holdover provisions of Article 16 of this Lease shall apply if a third party is unable to use the Premises as a
result thereof. Upon such expiration or termination, Tenant shall, without expense to Landlord, remove or cause to be removed from the Premises all telephone, data, and other cabling and wiring (including any cabling and wiring associated with the Wi-Fi Network, if any) installed or caused to be installed by Tenant (including any cabling and wiring, installed above the ceiling of the Premises or below the floor of the Premises), all debris and rubbish, and
such items of furniture, equipment, free-standing cabinet work, and other articles of personal property owned by Tenant or installed or placed by Tenant at its expense in the Premises, and such similar articles of any other persons claiming under
Tenant, as Landlord may, in its sole discretion, require to be removed, and Tenant shall repair at its own expense all damage to the Premises and Building resulting from such removal. In no event shall Tenant be required to remove (and Tenant shall
not remove) any of the Tenant Improvements installed by Landlord pursuant to Exhibit B. Tenant’s obligations under this Section 15.2 shall survive the expiration or earlier termination of this Lease. 

ARTICLE 16 

HOLDING OVER 
 If
Tenant holds over after the expiration of the Lease Term hereof, with or without the express or implied consent of Landlord, such tenancy shall not constitute a renewal hereof or an extension for any further term, and in such case Base Rent shall be
payable at a monthly rate (prorated for partial months) equal to one hundred fifty percent (150%) of the Base Rent applicable during the last rental period of the Lease Term under this Lease. Such tenancy shall be subject to every other term,
covenant and agreement contained herein. Landlord hereby expressly reserves the right to require Tenant to surrender possession of the Premises to Landlord as provided in this Lease upon the expiration or other termination of this Lease. The
provisions of this Article 16 shall not be deemed to limit or constitute a waiver of any other rights or remedies of Landlord provided herein or at law. If Tenant fails to surrender the Premises upon the termination or expiration of this Lease, in
addition to any other liabilities to Landlord accruing therefrom, Tenant shall protect, defend, indemnify and hold Landlord harmless from all loss, costs (including reasonable attorneys’ fees) and liability resulting from such failure,
including, without limiting the generality of the foregoing, any claims made by any succeeding tenant founded upon such failure to surrender, and any lost profits to Landlord resulting therefrom. 

  
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 ARTICLE 17 

ESTOPPEL CERTIFICATES 

Within ten (10) days following a request in writing by Landlord, Tenant shall execute and deliver to Landlord an estoppel certificate,
which, as submitted by Landlord, shall be in the form as may be reasonably required by any prospective mortgagee or purchaser of the Project (or any portion thereof), indicating therein any exceptions thereto that may exist at that time, and shall
also contain any other information reasonably requested by Landlord or Landlord’s mortgagee or Landlord’s prospective mortgagees. Tenant shall execute and deliver whatever other instruments may be reasonably required for such purposes.
Failure of Tenant to timely execute and deliver such estoppel certificate or other instruments shall constitute an acceptance of the Premises and an acknowledgment by Tenant that statements included in the estoppel certificate are true and correct,
without exception. Failure by Tenant to so deliver such estoppel certificate shall be a material default of the provisions of this Lease after the expiration of applicable notice and cure periods. In addition, Tenant shall be liable to Landlord, and
shall indemnify Landlord from and against any loss, cost, damage or expense, incidental, consequential, or otherwise, including attorneys’ fees, arising or accruing directly or indirectly, from any failure of Tenant to execute or deliver to
Landlord any such estoppel certificate. Upon request from time to time, Tenant agrees to provide to Landlord, within ten (10) days after Landlord’s delivery of written request therefor, current financial statements for Tenant, dated no
earlier than one (1) year prior to such written request, certified as accurate by Tenant or, if available, audited financial statements prepared by an independent certified public accountant with copies of the auditor’s statement. If any
guaranty is executed in connection with this Lease, Tenant also agrees to deliver to Landlord, within ten (10) days after Landlord’s delivery of written request therefor, current financial statements of the guarantor in a form consistent
with the foregoing criteria. Landlord shall hold all such statements confidentially. 
 ARTICLE 18 

SUBORDINATION 

This Lease is subject and subordinate to all present and future ground leases of the Project and to the lien of any mortgages or trust deeds,
now or hereafter in force against the Project, if any, and to all renewals, extensions, modifications, consolidations and replacements thereof, and to all advances made or hereafter to be made upon the security of such mortgages or trust deeds,
unless the holders of such mortgages or trust deeds, or the lessors under such ground lease, require in writing that this Lease be superior thereto; provided, however, that a condition precedent to the subordination of this Lease to any future
ground or underlying lease or to the lien of any future mortgage or deed of trust is that Landlord shall obtain for the benefit of Tenant a commercially reasonable subordination, non-disturbance and attornment
agreement from the landlord or lender of such future instrument. Tenant covenants and agrees in the event any proceedings are brought for the foreclosure of any such mortgage, or if any ground lease is terminated, to attorn, without any deductions
or set-offs whatsoever, to the purchaser upon any such foreclosure sale, or to the lessor of such ground lease, as the case may be, if so requested to do so by such purchaser or lessor, and to recognize such
purchaser or lessor as the lessor under this Lease. Tenant shall, within ten (10) days of request by Landlord, execute such further instruments or assurances as Landlord may reasonably deem necessary to evidence or confirm the subordination or
superiority of this Lease to any such mortgages, trust deeds, or ground leases. Tenant waives the provisions of any current or future statute, rule or law which may give or purport to give Tenant any right or election to terminate or otherwise
adversely affect this Lease and the obligations of the Tenant hereunder in the event of any foreclosure proceeding or sale. Within sixty (60) days after the execution of this Lease, Landlord shall use its commercially reasonable efforts to
obtain a non-disturbance agreement from the holder of any pre-existing mortgage encumbering the Building. In the event that Landlord is unable to provide the non-disturbance agreement within said sixty (60) days, then Tenant may at Tenant’s option, directly contact lender and attempt to negotiate for the execution and delivery of a non-disturbance agreement. 
 ARTICLE 19 

TENANT’S DEFAULTS; LANDLORD’S REMEDIES 

19.1 Events of Default by Tenant. All covenants and agreements to be kept or performed by Tenant under this Lease shall be performed by
Tenant at Tenant’s sole cost and expense and without any reduction of Rent. The occurrence of any of the following shall constitute a default of this Lease by Tenant: 

19.1.1 Any failure by Tenant to pay any Rent, Additional Rent or any other charge required to be paid under this Lease, or any part thereof,
within five (5) days of written notice that the same is past due; or 

  
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 19.1.2 Any failure by Tenant to observe or perform any other provision, covenant or
condition of this Lease to be observed or performed by Tenant (other than the payment of Rent or Additional Rent) where such failure continues for thirty (30) days after written notice thereof from Landlord to Tenant; provided however, that any
such notice shall be in lieu of, and not in addition to, any notice required under California Code of Civil Procedure Section 1161 or any similar or successor law; and provided further that if the nature of such default is such that the same
cannot reasonably be cured within a thirty (30)-day period, Tenant shall not be deemed to be in default if it diligently commences such cure within such period and thereafter diligently proceeds to rectify and
cure said default as soon as possible; or 
 19.1.3 Abandonment of the Premises by Tenant. 

19.1.4 Tenant makes an assignment for the benefit of creditors. 

19.1.5 A receiver, trustee or custodian is appointed to or does take title, possession or control of all or substantially all of Tenant’s
assets. 
 19.1.6 Tenant files a voluntary petition under the United States Bankruptcy Code or any successor statute (as the same may be
amended from time to time, (the “Bankruptcy Code”) or an order for relief is entered against Tenant pursuant to a voluntary or involuntary proceeding commenced under any chapter of the Bankruptcy Code. 

19.1.7 Any involuntary petition is filed against Tenant under any chapter of the Bankruptcy Code and is not dismissed within one hundred twenty
(120) days. 
 19.1.8 Intentionally Omitted. 

19.1.9 Tenant fails to deliver an estoppel certificate in accordance with Article 17 within three (3) days after written notice of such
failure. 
 19.1.10 Tenant’s interest in this Lease is attached, executed upon or otherwise judicially seized and such action is not
released within one hundred twenty (120) days of the action. 
 The notice periods provided herein are in lieu of, and not in addition
to, any notice periods provided by law. 
 19.2 Landlord’s Remedies Upon Default. Upon the occurrence of any such default by
Tenant, Landlord shall have, in addition to any other remedies available to Landlord at law or in equity, the option to pursue any one or more of the following remedies, each and all of which shall be cumulative and nonexclusive, without any notice
or demand whatsoever. 
 19.2.1 Terminate this Lease, in which event Tenant shall immediately surrender the Premises to Landlord, and if
Tenant fails to do so, Landlord may, without prejudice to any other remedy which it may have for possession or arrearages in rent, enter upon and take possession of the Premises and expel or remove Tenant and any other person who may be occupying
the Premises or any part thereof, without being liable for prosecution or any claim for damages therefor; and Landlord may recover from Tenant the following: 

(i) the worth at the time of award of any unpaid rent which has been earned at the time of such termination; plus 

(ii) the worth at the time of award of the amount by which the unpaid rent which would have been earned after termination until the time of
award exceeds the amount of such rental loss that Tenant proves could have been reasonably avoided; plus 
 (iii) the worth at the time of
award of the amount by which the unpaid rent for the balance of the Lease Term after the time of award exceeds the amount of such rental loss that Tenant proves could have been reasonably avoided; plus 

  
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 (iv) any other amount necessary to compensate Landlord for all the detriment proximately
caused by Tenant’s failure to perform its obligations under this Lease or which in the ordinary course of things would be likely to result therefrom, specifically including but not limited to, brokerage commissions and advertising expenses
incurred, expenses of remodeling the Premises or any portion thereof for a new tenant, whether for the same or a different use, and any special concessions made to obtain a new tenant; plus 

(v) at Landlord’s election, such other amounts in addition to or in lieu of the foregoing as may be permitted from time to time by
applicable law. 
 The term “rent” as used in this Section 19.2 shall be deemed to be and to mean all sums of every nature required to be
paid by Tenant pursuant to the terms of this Lease, whether to Landlord or to others. As used in Sections 19.2.1(i) and (ii), above, the “worth at the time of award” shall be computed by allowing interest at the Interest Rate set forth in
Section 4.5 above. As used in Section 19.2.1(iii) above, the “worth at the time of award” shall be computed by discounting such amount at the discount rate of the Federal Reserve Bank of San Francisco at the time of award plus
one percent (1%). 
 19.2.2 Landlord shall have the remedy described in California Civil Code Section 1951.4 (lessor may continue lease
in effect after lessee’s breach and abandonment and recover rent as it becomes due, if lessee has the right to sublet or assign, subject only to reasonable limitations). Accordingly, if Landlord does not elect to terminate this Lease on account
of any default by Tenant, Landlord may, from time to time, without terminating this Lease, enforce all of its rights and remedies under this Lease, including the right to recover all rent as it becomes due. 

19.2.3 Landlord may, but shall not be obligated to, make any such payment or perform or otherwise cure any such obligation, provision, covenant
or condition on Tenant’s part to be observed or performed (and may enter the Premises for such purposes). In the event of Tenant’s failure to perform any of its obligations or covenants under this Lease, and such failure to perform poses a
material risk of injury or harm to persons or damage to or loss of property, then Landlord shall have the right to cure or otherwise perform such covenant or obligation at any time after such failure to perform by Tenant, whether or not any such
notice or cure period set forth in Section 19.1 above has expired. Any such actions undertaken by Landlord pursuant to the foregoing provisions of this Section 19.2.3 shall not be deemed a waiver of Landlord’s rights and remedies as a
result of Tenant’s failure to perform and shall not release Tenant from any of its obligations under this Lease. 
 19.3 Payment by
Tenant. Tenant shall pay to Landlord, within ten (10) days after delivery by Landlord to Tenant of statements therefor: (i) sums equal to expenditures reasonably made and obligations incurred by Landlord in connection with
Landlord’s performance or cure of any of Tenant’s obligations pursuant to the provisions of Section 19.2.3 above; and (ii) sums equal to all expenditures made and obligations incurred by Landlord in collecting or attempting to
collect the Rent or in enforcing or attempting to enforce any rights of Landlord under this Lease or pursuant to law, including, without limitation, all legal fees and other amounts so expended. Tenant’s obligations under this Section 19.3
shall survive the expiration or sooner termination of the Lease Term. 
 19.4 Sublessees of Tenant. If Landlord elects to terminate
this Lease on account of any default by Tenant, as set forth in this Article 19, Landlord shall have the right to terminate any and all subleases, licenses, concessions or other consensual arrangements for possession entered into by Tenant and
affecting the Premises or may, in Landlord’s sole discretion, succeed to Tenant’s interest in such subleases, licenses, concessions or arrangements. If Landlord elects to succeed to Tenant’s interest in any such subleases, licenses,
concessions or arrangements, Tenant shall, as of the date of notice by Landlord of such election, have no further right to or interest in the rent or other consideration receivable thereunder. 

19.5 Waiver of Default. No waiver by Landlord of any violation or breach by Tenant of any of the terms, provisions and covenants herein
contained shall be deemed or construed to constitute a waiver of any other or later violation or breach by Tenant of the same or any other of the terms, provisions, and covenants herein contained. Forbearance by Landlord in enforcement of one or
more of the remedies herein provided upon a default by Tenant shall not be deemed or construed to constitute a waiver of such default. The acceptance of any Rent hereunder by Landlord following the occurrence of any default, whether or not known to
Landlord, shall not be deemed a waiver of any such default, except only a default in the payment of the Rent so accepted. 

  
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 19.6 Efforts to Relet. For the purposes of this Article 19, Tenant’s right to
possession shall not be deemed to have been terminated by efforts of Landlord to relet the Premises, by its acts of maintenance or preservation with respect to the Premises, or by appointment of a receiver to protect Landlord’s interests
hereunder. The foregoing enumeration is not exhaustive, but merely illustrative of acts which may be performed by Landlord without terminating Tenant’s right to possession. 

19.7 Bankruptcy. In the event a debtor, trustee or debtor in possession under the Bankruptcy Code, or another person with similar
rights, duties and powers under any other applicable laws, proposes to cure any default under this Lease or to assume or assign this Lease and is obliged to provide adequate assurance to Landlord that (a) a default shall be cured,
(b) Landlord shall be compensated for its damages arising from any breach of this Lease and (c) future performance of Tenant’s obligations under this Lease shall occur, then such adequate assurances shall include any or all of the
following, as designated by Landlord in its sole and absolute discretion: 
 (i) Those acts specified in the Bankruptcy Code or other
applicable laws as included within the meaning of “adequate assurance,” even if this Lease does not concern a shopping center or other facility described in such applicable laws; 

(ii) A prompt cash payment to compensate Landlord for any monetary defaults or actual damages arising directly from a breach of this Lease;

 (iii) A cash deposit in an amount at least equal to the then-current amount of the Security Deposit; or 

(iv) The assumption or assignment of all of Tenant’s interest and obligations under this Lease. 

ARTICLE 20 

SECURITY DEPOSIT 

Concurrent with Tenant’s execution of this Lease, Tenant shall deposit with Landlord a security deposit (the “Security
Deposit”) in the amount set forth in Section 10 of the Summary. The Security Deposit shall be held by Landlord as security for the faithful performance by Tenant of all the terms, covenants, and conditions of this Lease to be kept and
performed by Tenant during the Lease Term. If Tenant defaults with respect to any provisions of this Lease, including, but not limited to, the provisions relating to the payment of Rent, Landlord may, but shall not be required to, use, apply or
retain all or any part of the Security Deposit for the payment of any Rent or any other sum in default, or for the payment of any amount that Landlord may spend or become obligated to spend by reason of Tenant’s default, or to compensate
Landlord for any other loss or damage that Landlord may suffer by reason of Tenant’s default. If any portion of the Security Deposit is so used or applied, Tenant shall, within five (5) business days after written demand therefor, deposit
cash with Landlord in an amount sufficient to restore the Security Deposit to its original amount, and Tenant’s failure to do so shall be a default under this Lease. If Tenant shall fully and faithfully perform every provision of this Lease to
be performed by it, the Security Deposit, or any balance thereof, shall be returned to Tenant, or, at Landlord’s option, to the last assignee of Tenant’s interest hereunder, within sixty (60) days following the expiration of the Lease
Term. Tenant shall not be entitled to any interest on the Security Deposit. Tenant hereby waives the provisions of Section 1950.7 of the California Civil Code, and all other provisions of law, now or hereafter in force, which provide that
Landlord may claim from a security deposit only those sums reasonably necessary to remedy defaults in the payment of rent, to repair damage caused by Tenant or to clean the Premises, it being agreed that Landlord may, in addition, claim those sums
reasonably necessary to compensate Landlord for any other loss or damage, foreseeable or unforeseeable, caused by the act or omission of Tenant or any officer, employee, agent or invitee of Tenant. In the event of bankruptcy or other debtor-creditor
proceedings against Tenant, the Security Deposit shall be deemed to be applied first to the payment of Rent and other charges due Landlord for all periods prior to the filing of such proceedings. 

  
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 ARTICLE 21 

COMPLIANCE WITH LAW 

Tenant shall not do anything or suffer anything to be done in or about the Premises which will in any way conflict with any law, statute,
ordinance or other governmental rule, regulation or requirement now in force or which may hereafter be enacted or promulgated. At its sole cost and expense, Tenant shall promptly comply with all such governmental measures, other than the making of
structural changes or changes to the Building’s life safety system or alterations that would be considered capital expenditures (collectively the “Excluded Changes”); provided, however, to the extent such Excluded Changes are
required due to or triggered by Tenant’s improvements or alterations to and/or manner of use of the Premises, Landlord shall perform such work, at Tenant’s cost (which shall be paid by Tenant to Landlord within ten (10) days after
Tenant’s receipt of invoice therefor from Landlord). In addition, Tenant shall fully comply with all present or future legally required programs intended to manage parking, transportation or traffic in and around the Project, and in connection
therewith, Tenant shall take responsible action for the transportation planning and management of all employees located at the Premises by working directly with Landlord, any governmental transportation management organization or any other
transportation-related committees or entities. The judgment of any court of competent jurisdiction or the admission of Tenant in any judicial action, regardless of whether Landlord is a party thereto, that Tenant has violated any of said
governmental measures, shall be conclusive of that fact as between Landlord and Tenant. 
 ARTICLE 22 

ENTRY BY LANDLORD 

Landlord reserves the right at all reasonable times and upon reasonable notice to Tenant (of not less than one (1) business day except in
the event of an emergency) to enter the Premises to: (i) inspect them; (ii) show the Premises to prospective purchasers, mortgagees or tenants, or to the ground lessors; (iii) to post notices of nonresponsibility; or (iv) alter,
improve or repair the Premises or the Building if necessary to comply with current building codes or other applicable laws, or for structural alterations, repairs or improvements to the Building, or as Landlord may otherwise deem necessary.
Notwithstanding anything to the contrary contained in this Article 22, Landlord may enter the Premises at any time, without notice to Tenant, in emergency situations and/or to perform janitorial or other services required of Landlord pursuant to
this Lease. Any such entries shall be without the abatement of Rent and shall include the right to take such reasonable steps as required to accomplish the stated purposes. Tenant hereby waives any claims for damages or for any injuries or
inconvenience to or interference with Tenant’s business, lost profits, any loss of occupancy or quiet enjoyment of the Premises, and any other loss occasioned thereby. For each of the above purposes, Landlord shall at all times have a key with
which to unlock all the doors in the Premises, excluding Tenant’s vaults, safes and special security areas designated in advance by Tenant. In an emergency, Landlord shall have the right to enter without notice and use any means that Landlord
may deem proper to open the doors in and to the Premises. Any entry into the Premises in the manner hereinbefore described shall not be deemed to be a forcible or unlawful entry into, or a detainer of, the Premises, or an actual or constructive
eviction of Tenant from any portion of the Premises. Notwithstanding the foregoing, any entry by Landlord or Landlord’s agents shall not impair Tenant’s operations more than reasonably necessary, and shall comply with Tenant’s
reasonable security measures. 
 ARTICLE 23 

PARKING 

Throughout the Lease Term, Tenant shall have the right to use, on a “first-come, first-serve” basis, in common with other tenants of
the Building and free of parking charges, the number of unreserved parking spaces set forth in Section 12 of the Summary, which unreserved parking spaces are located in the Parking Facility servicing the Building as shall be designated by
Landlord from time to time for unreserved parking for the tenants of the Building. Tenant’s continued right to use the parking spaces is conditioned upon (i) Tenant abiding by (A) the Parking Rules and Regulations which are in effect
on the date hereof, as set forth in the attached Exhibit D and all reasonable modifications and additions thereto which are prescribed from time to time for the orderly operation and use of the Parking Facility by Landlord, and/or
Landlord’s Parking Operator (as defined below), and (B) all recorded covenants, conditions and restrictions affecting the Building, and (ii) upon Tenant’s cooperation in seeing that Tenant’s employees

  
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and visitors also comply with the Parking Rules and Regulations (and all such modifications and additions thereto, as the case may be), any such other rules and regulations and covenants,
conditions and restrictions. Landlord (and/or any other owners of the Project) specifically reserve the right to change the size, configuration, design, layout, location and all other aspects of the Parking Facility (including without limitation,
implementing paid visitor parking), and Tenant acknowledges and agrees that Landlord may, without incurring any liability to Tenant and without any abatement of Rent under this Lease, from time to time, temporarily
close-off or restrict access to the Parking Facility, so long as the same does not (other than on a temporary basis of less than one (1) week) reduce the number and availability of parking spaces
available to Tenant under this Lease. Landlord may delegate its responsibilities hereunder to a parking operator (the “Parking Operator”) in which case the Parking Operator shall have all the rights of control attributed hereby to
Landlord. Any parking tax or other charges imposed by governmental authorities in connection with the use of such parking shall be paid directly by Tenant or the parking users, or, if directly imposed against Landlord, Tenant shall reimburse
Landlord for all such taxes and/or charges thirty (30) days after Landlord’s demand therefor. The parking rights provided to Tenant pursuant to this Article 23 are provided solely for use by Tenant’s own personnel and such rights may
not be transferred, assigned, subleased or otherwise alienated by Tenant without Landlord’s prior approval, except in connection with an assignment of this Lease or sublease of the Premises made in accordance with Article 14 above. All visitor
parking by Tenant’s visitors shall be subject to availability, as reasonably determined by Landlord (and/or the Parking Operator, as the case may be), parking in such visitor parking areas as may be designated by Landlord (and/or the Parking
Operator from time to time, and payment by such visitors of the prevailing visitor parking rate (if any) charged by Landlord (and/or the Parking Operator) from time to time. 

ARTICLE 24 

MISCELLANEOUS PROVISIONS 

24.1 Terms; Captions. The necessary grammatical changes required to make the provisions hereof apply either to corporations or
partnerships or individuals, men or women, as the case may require, shall in all cases be assumed as though in each case fully expressed. The captions of Articles and Sections are for convenience only and shall not be deemed to limit, construe,
affect or alter the meaning of such Articles and Sections. 
 24.2 Binding Effect. Each of the provisions of this Lease shall extend
to and shall, as the case may require, bind or inure to the benefit not only of Landlord and of Tenant, but also of their respective successors or assigns, provided this clause shall not permit any assignment by Tenant contrary to the provisions of
Article 14 above. 
 24.3 No Waiver. No waiver of any provision of this Lease shall be implied by any failure of a party to enforce
any remedy on account of the violation of such provision, even if such violation shall continue or be repeated subsequently, any waiver by a party of any provision of this Lease may only be in writing, and no express waiver shall affect any
provision other than the one specified in such waiver and that one only for the time and in the manner specifically stated. No receipt of monies by Landlord from Tenant after the termination of this Lease shall in any way alter the length of the
Lease Term or of Tenant’s right of possession hereunder or after the giving of any notice shall reinstate, continue or extend the Lease Term or affect any notice given Tenant prior to the receipt of such monies, it being agreed that after the
service of notice or the commencement of a suit or after final judgment for possession of the Premises, Landlord may receive and collect any Rent due, and the payment of said Rent shall not waive or affect said notice, suit or judgment. 

24.4 Modification of Lease. If any current or prospective mortgagee or ground lessor for the Project requires modifications to this
Lease, which modifications will not cause an increased cost or expense to Tenant or in any other way materially and adversely change the rights and obligations of Tenant hereunder or interfere with Tenant’s use of or access to the Premises,
then and in such event, Tenant agrees that this Lease may be so modified and agrees to execute whatever reasonable documents are required therefor and deliver the same to Landlord within ten (10) days following the request therefor. If Landlord
or any such current or prospective mortgagee or ground lessor require execution of a short form of Lease for recording, containing, among other customary provisions, the names of the parties, a description of the Premises and the Lease Term, Tenant
shall execute such short form of Lease and to deliver the same to Landlord within ten (10) days following the request therefor. 

  
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 24.5 Transfer of Landlord’s Interest. Landlord has the right to transfer all or
any portion of its interest in the Project, the Building and/or in this Lease, and upon any such transfer, Landlord shall automatically be released from all liability under this Lease and Tenant shall look solely to such transferee for the
performance of Landlord’s obligations hereunder after the date of transfer. The liability of any transferee of Landlord shall be limited to the amount of the interest of such transferee in the Project including all proceeds therefrom and such
transferee shall otherwise be without personal liability under this Lease, and Tenant hereby expressly waives and releases such personal liability on behalf of itself and all persons claiming by, through or under Tenant. Landlord may also assign its
interest in this Lease to a mortgage lender as additional security but such assignment shall not release Landlord from its obligations hereunder and Tenant shall continue to look to Landlord for the performance of its obligations hereunder. Except
for Landlord’s liability as limited under the second sentence of this Section 24.5, neither Landlord nor any of its affiliates, nor any of their respective partners, shareholders, directors, officers, employees, members or agents shall be
personally liable for Landlord’s obligations or any deficiency under this Lease, and service of process shall not be made against any shareholder, member, director, officer, employee or agent of Landlord or any of Landlord’s affiliates. No
partner, shareholder, director, officer, employee, member or agent of Landlord or any of its affiliates shall be sued or named as a party in any suit or action, and service of process shall not be made against any partner or member of Landlord
except as may be necessary to secure jurisdiction of the partnership, joint venture or limited liability company, as applicable. No partner, shareholder, director, officer, employee, member or agent of Landlord or any of its affiliates shall be
required to answer or otherwise plead to any service of process, and no judgment shall be taken or writ of execution levied against any partner, shareholder, director, officer, employee, member or agent of Landlord or any of its affiliates. 

24.6 Prohibition Against Recording. Except as provided in Section 24.4 of this Lease, neither this Lease, nor any memorandum,
affidavit or other writing with respect thereto, shall be recorded by Tenant or by anyone acting through, under or on behalf of Tenant, and the recording thereof in violation of this provision shall make this Lease null and void at Landlord’s
election. 
 24.7 Landlord’s Title; Air Rights. Landlord’s title is and always shall be paramount to the title of Tenant.
Nothing herein contained shall empower Tenant to do any act which can, shall or may encumber the title of Landlord. No rights to any view or to light or air over any property, whether belonging to Landlord or any other person, are granted to Tenant
by this Lease. 
 24.8 Tenant’s Signs. Tenant shall be entitled, at Landlord’s initial sole cost and expense, to one
(1) identification sign on or near the entry doors of the Premises and for multi-tenant floors (if any) on which the Premises are located, one (1) identification or directional sign, as designated by Landlord, in the elevator lobby on the
floor on which the Premises are located and identification on the directory in the Building and or directional signs; any Landlord approved changes to such signage shall be at Tenant’s sole cost and expense. Such signs shall be installed by a
signage contractor designated by Landlord. The location, quality, design, style, lighting and size of such signs shall be consistent with the Landlord’s Building standard signage program and shall be subject to Landlord’s prior written
approval, in its reasonable discretion. Upon the expiration or earlier termination of this Lease, Tenant shall be responsible, at its sole cost and expense, for the removal of such signage and the repair of all damage to the Building caused by such
removal. Except for such identification signs, Tenant may not install any signs on the exterior or roof of the Building, the Other Future Building or the common areas of the Building or the Project. Any signs, window coverings, or blinds (even if
the same are located behind the Landlord approved window coverings for the Building), or other items visible from the exterior of the Premises or Building are subject to the prior approval of Landlord, in its sole and absolute discretion. 

24.9 Relationship of Parties. Nothing contained in this Lease shall be deemed or construed by the parties hereto or by any third party
to create the relationship of principal and agent, partnership, joint venturer or any association between Landlord and Tenant, it being expressly understood and agreed that neither the method of computation of Rent nor any act of the parties hereto
shall be deemed to create any relationship between Landlord and Tenant other than the relationship of landlord and tenant. 
 24.10
Application of Payments. Landlord shall have the right to apply payments received from Tenant pursuant to this Lease, regardless of Tenant’s designation of such payments, to satisfy any obligations of Tenant hereunder, in such order and
amounts as Landlord, in its sole discretion, may elect. 
 24.11 Time of Essence. Time is of the essence of this Lease and each of its
provisions. 

  
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 24.12 Partial Invalidity. If any term, provision or condition contained in this Lease
shall, to any extent, be invalid or unenforceable, the remainder of this Lease, or the application of such term, provision or condition to persons or circumstances other than those with respect to which it is invalid or unenforceable, shall not be
affected thereby, and each and every other term, provision and condition of this Lease shall be valid and enforceable to the fullest extent possible permitted by law. 

24.13 No Warranty. In executing and delivering this Lease, Tenant has not relied on any representation, including, but not limited to,
any representation whatsoever as to the amount of any item comprising Additional Rent or the amount of the Additional Rent in the aggregate or that Landlord is furnishing the same services to other tenants, at all, on the same level or on the same
basis, or any warranty or any statement of Landlord which is not set forth herein or in one or more of the Exhibits attached hereto. 
 24.14
Landlord Exculpation. Notwithstanding anything in this Lease to the contrary, and notwithstanding any applicable law to the contrary, the liability of Landlord and the Landlord Parties under this Lease (including any successor landlord) and
any recourse by Tenant against Landlord or the Landlord Parties shall be limited solely and exclusively to an amount which is equal to the ownership interest of Landlord in the Project (excluding any proceeds thereof), and neither Landlord, nor any
of the Landlord Parties (except for Landlord’s liability as limited in the preceding portion of this sentence) shall have any personal liability therefor, and Tenant hereby expressly waives and releases such personal liability on behalf of
itself and all persons claiming by, through or under Tenant. 
 24.15 Entire Agreement. There are no oral agreements between the
parties hereto affecting this Lease and this Lease supersedes and cancels any and all previous negotiations, arrangements, brochures, agreements and understandings, if any, between the parties hereto or displayed by Landlord to Tenant with respect
to the subject matter thereof, and none thereof shall be used to interpret or construe this Lease. This Lease and any side letter or separate agreement executed by Landlord and Tenant in connection with this Lease and dated of even date herewith
contain all of the terms, covenants, conditions, warranties and agreements of the parties relating in any manner to the rental, use and occupancy of the Premises, shall be considered to be the only agreement between the parties hereto and their
representatives and agents, and none of the terms, covenants, conditions or provisions of this Lease can be modified, deleted or added to except in writing signed by the parties hereto. All negotiations and oral agreements acceptable to both parties
have been merged into and are included herein. There are no other representations or warranties between the parties, and all reliance with respect to representations is based totally upon the representations and agreements contained in this Lease.

 24.16 Right to Lease. Landlord reserves the absolute right to effect such other tenancies in the Building, the Other Future
Building and/or in any other building and/or any other portion of the Project as Landlord in the exercise of its sole business judgment shall determine to best promote the interests of the Project. Tenant does not rely on the fact, nor does Landlord
represent, that any specific tenant or type or number of tenants shall, during the Lease Term, occupy any space in the Building, the Other Future Building or Project. 

24.17 Force Majeure. Any prevention, delay or stoppage due to strikes, lockouts, labor disputes, acts of God, inability to obtain
services, labor, or materials or reasonable substitutes therefor, governmental actions, civil commotions, fire or other casualty, and other causes beyond the reasonable control of the party obligated to perform, except with respect to the
obligations imposed with regard to Rent and other charges to be paid by Tenant pursuant to this Lease (collectively, the “Force Majeure”), notwithstanding anything to the contrary contained in this Lease, shall excuse the
performance of such party for a period equal to any such prevention, delay or stoppage and, therefore, if this Lease specifies a time period for performance of an obligation of either party, that time period shall be extended by the period of any
delay in such party’s performance caused by a Force Majeure; provided, however, Tenant’s rights to abate rent or terminate this Lease shall not be delayed as a result thereof. 

24.18 Waiver of Redemption by Tenant. Tenant hereby waives for Tenant and for all those claiming under Tenant all right now or hereafter
existing to redeem by order or judgment of any court or by any legal process or writ, Tenant’s right of occupancy of the Premises after any termination of this Lease. 

  
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 24.19 Notices. All notices, demands, statements or communications (collectively,
“Notices”) given or required to be given by either party to the other hereunder shall be in writing, shall be sent by United States certified or registered mail, postage prepaid, return receipt requested, or delivered personally
(i) to Tenant at the appropriate address set forth in Section 5 of the Summary, or to such other place as Tenant may from time to time designate in a Notice to Landlord; or (ii) to Landlord at the addresses set forth in Section 3
of the Summary, or to such other firm or to such other place as Landlord may from time to time designate in a Notice to Tenant. Any Notice will be deemed given three (3) business days after the date it is mailed as provided in this
Section 24.19 or upon the date personal delivery is made or rejected. If Tenant is notified of the identity and address of Landlord’s mortgagee or ground lessor, Tenant shall give to such mortgagee or ground lessor written notice of any
default by Landlord under the terms of this Lease by registered or certified mail, and such mortgagee or ground lessor shall be given a reasonable opportunity to cure such default prior to Tenant’s exercising any remedy available to Tenant.

 24.20 Joint and Several. If there is more than one person or entity executing this Lease as Tenant, the obligations imposed upon
such persons and entities under this Lease are and shall be joint and several. 
 24.21 Representations. Tenant guarantees, warrants
and represents that (a) Tenant is duly incorporated or otherwise established or formed and validly existing under the laws of its state of incorporation, establishment or formation, (b) Tenant has and is duly qualified to do business in
the state in which the Project is located, (c) Tenant has full corporate, partnership, trust, association or other appropriate power and authority to enter into this Lease and to perform all Tenant’s obligations hereunder, (d) each
person (and all of the persons if more than one signs) signing this Lease on behalf of Tenant is duly and validly authorized to do so and (e) neither (i) the execution, delivery or performance of this Lease nor (ii) the consummation of the
transactions contemplated hereby will violate or conflict with any provision of documents or instruments under which Tenant is constituted or to which Tenant is a party. In addition, Tenant guarantees, warrants and represents that, (y) to its
knowledge, none of its members, shareholders or other equity owners or any of their respective employees, officers, directors, representatives or agents is a person or entity with whom U.S. persons or entities are restricted from doing business
under regulations of the Office of Foreign Asset Control (“OFAC”) of the Department of the Treasury (including those named on OFAC’s Specially Designated and Blocked Persons List) or under any statute, executive order
(including the September 24, 2001, Executive Order Blocking Property and Prohibiting Transactions with Persons Who Commit, Threaten to Commit, or Support Terrorism) or other similar governmental action. 

24.22 Jury Trial; Attorneys’ Fees. IF EITHER PARTY COMMENCES LITIGATION AGAINST THE OTHER FOR THE SPECIFIC PERFORMANCE OF THIS
LEASE, FOR DAMAGES FOR THE BREACH HEREOF OR OTHERWISE FOR ENFORCEMENT OF ANY REMEDY HEREUNDER, THE PARTIES HERETO AGREE TO AND HEREBY DO WAIVE ANY RIGHT TO A TRIAL BY JURY. In the event of any such commencement of litigation, the prevailing party
shall be entitled to recover from the other party such costs and reasonable attorneys’ fees as may have been incurred, including any and all costs incurred in enforcing, perfecting and executing such judgment. 

24.23 Governing Law. This Lease shall be construed and enforced in accordance with the laws of the state in which the Project is
located. 
 24.24 Submission of Lease. Submission of this instrument for examination or signature by Tenant does not constitute a
reservation of or an option for lease, and it is not effective as a lease or otherwise until execution and delivery by both Landlord and Tenant. 

24.25 Brokers. Landlord and Tenant each hereby represents and warrants to the other party that it (i) has had no dealings with any
real estate broker or agent in connection with the negotiation of this Lease, excepting only the real estate brokers or agents specified in Section 11 of the Summary (collectively, the “Brokers”), and (ii) knows of no
other real estate broker or agent who is entitled to a commission in connection with this Lease. Each party agrees to indemnify and defend the other party against and hold the other party harmless from any and all claims, demands, losses,
liabilities, lawsuits, judgments, and costs and expenses (including without limitation reasonable attorneys’ fees) with respect to any leasing commission or equivalent compensation alleged to be owing on account of the indemnifying party’s
dealings with any real estate broker or agent in connection with this Lease other than the Brokers. 

  
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 24.26 Independent Covenants. This Lease shall be construed as though the covenants
herein between Landlord and Tenant are independent and not dependent and Tenant hereby expressly waives the benefit of any statute to the contrary and agrees that if Landlord fails to perform its obligations set forth herein, Tenant shall not be
entitled to make any repairs or perform any acts hereunder at Landlord’s expense or to any setoff of the Rent or other amounts owing hereunder against Landlord; provided, however, that the foregoing shall in no way impair the right of Tenant to
commence a separate action against Landlord for any violation by Landlord of the provisions hereof so long as notice is first given to Landlord and any holder of a mortgage or deed of trust covering the Building, Project or any portion thereof, of
whose address Tenant has theretofore been notified, and an opportunity is granted to Landlord and such holder to correct such violations as provided above. 

24.27 Building Name and Signage. Landlord shall have the right at any time to change the name(s) of the Building, the Other Future
Building and Project and to install, affix and maintain any and all signs on the exterior and on the interior of the Building, the Other Future Building and any portion of the Project as Landlord may, in Landlord’s sole discretion, desire.
Tenant shall not use the names of the Building, the Other Future Building or Project or use pictures or illustrations of the Building, the Other Future Building or Project in advertising or other publicity, without the prior written consent of
Landlord. 
 24.28 Building Directory. If the Building contains a tenant name directory, Landlord shall include Tenant’s name and
location in the Building on one (1) line on the Building directory. The initial cost of such directory signage shall be paid for by Landlord, but any subsequent charges thereto shall be at Tenant’s cost. 

24.29 Confidentiality. Except as may be required by law or in litigation with Landlord, Tenant shall use commercially reasonable efforts
to keep the content of this Lease and any related documents confidential and not disclose such confidential information to any person or entity other than Tenant’s financial, legal, and space planning consultants, proposed subtenants and
current and proposed lenders, investors and business partners. 
 24.30 Landlord’s Construction. Except as specifically set forth
in this Lease or in the Tenant Work Letter: (i) Landlord has no obligation to alter, remodel, improve, renovate, repair or decorate the Premises, the Building, the Other Future Building, the Project, or any part thereof; and (ii) no
representations or warranties respecting the condition of the Premises, the Building, the Other Future Building or the Project have been made by Landlord to Tenant. Tenant acknowledges that prior to and during the Lease Term, Landlord (and/or any
common area association) will be completing construction and/or demolition work pertaining to various portions of the Building, the Other Future Building, the Premises, and/or the Project, including without limitation, landscaping and tenant
improvements for premises for other tenants and, at Landlord’s sole election, such other buildings, improvements, landscaping and other facilities within or as part of the Project as Landlord (and/or such common area association) shall from
time to time desire (collectively, the “Construction”). In connection with such Construction, Landlord may, among other things, erect scaffolding or other necessary structures in the Building and/or the Other Future Building, limit
or eliminate access to portions of the Project, including portions of the common areas, or perform work in the Building, the Other Future Building and/or the Project, which work may create noise, dust or leave debris in the Building, the Other
Future Building and/or the Project. Notwithstanding the foregoing, Landlord’s Construction shall be performed in such a manner as to not unreasonably interfere with Tenant’s access to or use of the Premises for Tenant’s business
purposes, or materially decrease Tenant’s rights or increase Tenant’s obligations under this Lease. Tenant hereby agrees that such Construction and Landlord’s actions in connection with such Construction shall in no way constitute a
constructive eviction of Tenant nor entitle Tenant to any abatement of Rent so long as such Construction does not unreasonably interfere with Tenant’s access to or use of the Premises for Tenant’s business purposes. Landlord shall have no
responsibility or for any reason be liable to Tenant for any direct or indirect injury to or interference with Tenant’s business arising from such Construction, nor shall Tenant be entitled to any compensation or damages from Landlord for loss
of the use of the whole or any part of the Premises or of Tenant’s personal property or improvements resulting from such Construction or Landlord’s actions in connection with such Construction, or for any inconvenience or annoyance
occasioned by such Construction or Landlord’s actions in connection with such Construction. Landlord reserves full control over the Project to the extent not inconsistent with Tenant’s enjoyment the same as provided in this Lease. This
reservation includes Landlord’s right to subdivide the Project and convert portions of the Project to condominium units, change the size of the Project by selling all or a portion of the Project or adding real property and any improvements
thereon to the Project; grant easements and licenses to third parties and maintain or establish ownership of the Buildings separate from the fee title to the Project. 

  
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 24.31 Intentionally Omitted. 

24.32 Net Lease. This Lease shall be deemed and construed to be an “absolute net lease” as provided herein and, except as
herein expressly provided, Landlord shall receive all payments required to be made by Tenant free from all charges, assessments, impositions, expenses and deductions of any and every kind or nature whatsoever. Landlord shall not be required to
furnish any services or facilities or to make any repairs, replacements or alterations of any kind in or on the Premises except as specifically provided herein. 

24.33 Access Control. Landlord shall provide certain access control services for the Building on a 24 hours a day, 7 days a week and 365
days a year basis. Tenant recognizes that any access control services provided by Landlord at the Building is for the protection of Landlord’s property and under no circumstances shall Landlord be responsible for, and Tenant waives any rights
with respect to, providing security or other protection for Tenant or its employees, invitees or property in or about the Premises or the Project. Landlord shall not be liable to Tenant, and Tenant hereby waives any claim against Landlord, for, and
expressly assumes the risk of (i) any unauthorized or criminal entry of third parties into the Premises or the Building, (ii) any damage to persons in or about the Premises or the Project, or (iii) any loss of property in and about
the Premises or the Building, by or from any unauthorized or criminal acts of third parties, regardless of any action, inaction, failure, breakdown, malfunction and/or insufficiency of the security services provided by Landlord or any actual or
alleged passive or active negligence of Landlord. 
 24.34 Performing Arts Center. The Building includes an approximately 235-seat performing arts center (the “PAC”). Booking of the PAC shall be subject to availability on a shared basis with all other tenants in the Project. Tenant shall follow those procedures
promulgated by Landlord from time to time to schedule use of the PAC. Tenant shall have the right to use the PAC so long as Tenant has scheduled such use of the PAC in advance in accordance with Landlord procedures. 

24.35 Fitness Center. There is a fitness center in the Building located on the second floor (the “Fitness Center”) for
the non-exclusive use by Landlord, Tenant and other tenants of the Building, subject to the reasonable rules adopted from time to time by Landlord for such usage. The costs of operating and maintaining the
Fitness Center shall be included in Operating Expenses. Use of the Fitness Center by Tenant shall be at the sole risk of Tenant and Landlord assumes no liability or risk associated with Tenant’s use of the Fitness Center. Tenant acknowledges
that use of the Fitness Center is unsupervised and unattended. Tenant acknowledges that each officer or employee of Tenant who desires to use the Fitness Center will be required to sign and deliver to Landlord, a commercially reasonable release of
liability agreement in such form as is customary in the industry and as may be revised by Landlord from time to time. Landlord shall be permitted to charge any individual user of the Fitness Center an annual administrative fee for the cost of such
user’s access card and expenses relating to recording keeping for the individual user. Tenant shall be responsible for payment of such access card for each of Tenant’s employees who requests access to the Fitness Center in a Lease Year.
The current annual administrative fee for such access is $30.00 per user. Landlord shall have the right to hereafter increase such fee to the extent necessary to reimburse Landlord for increases in the cost to Landlord to supply and administer the
access cards. The administrative fee payable by Tenant to Landlord for each of Tenant’s officers and employees shall be deemed Additional Rent hereunder. Landlord shall have the right to relocate the fitness center in the Project. 

24.36 Sustainability. 

24.36.1 Sustainable Building Operations. 

(a) This Building is or may become in the future certified under the Green Building Initiative’s Green GlobesTM for Continual Improvement of Future Buildings (Green GlobesTM-CIEB), the U.S. Green Building Council’s Leadership in Energy and Environmental Design (LEED) rating system, or operated pursuant
to Landlord’s sustainable building practices. Landlord’s sustainability practices address whole-building operations and maintenance issues including chemical use; indoor air quality; energy efficiency; water efficiency; recycling programs;
exterior maintenance programs; and systems upgrades to meet green building energy, water, Indoor Air Quality, and lighting performance standards. Notwithstanding the foregoing, Tenant shall not be required to comply with any Green Building
Initiatives or other rating systems as set forth above until the Building is certified as such, and Tenant shall only be required to comply with such Green Building Initiatives with respect to any upgrades, alterations or improvements made by Tenant
after the Building is certified as set forth above. In no event shall Tenant be required to make changes, improvements and/or other repairs or replacements to the Premises in order to make the Premises compliant with the above stated initiatives and
rating systems. All construction and maintenance methods and procedures, material purchase, and disposal of waste must be in compliance with minimum standards and specifications, in addition to all applicable laws. 

  
 -39- 

 (b) Tenant shall use proven energy and carbon reduction measures, including energy
efficient bulbs in task lighting; use of lighting controls; daylighting measures to avoid over-lighting interior spaces; closing shades on the south side of the Building to avoid over heating the space; turning off lights and equipment at the end of
the work day; and purchasing, with respect to any new equipment that Tenant purchases for the Premises, ENERGY STAR® qualified equipment, if applicable, including but not limited to lighting,
office equipment, commercial and residential quality kitchen equipment, vending and ice machines; purchasing products certified by the U.S. EPA’s Water Sense® program. Tenant shall not be
required to replace any existing equipment used by Tenant as of the date of this Lease which Tenant intends to install in the Premises in order to comply with the provisions of this Section 24.36(b). 

24.36.2 Recycling and Waste Management. Tenant covenants and agrees, at its sole cost and expense: (a) to comply with all present
and future laws, orders and regulations of the Federal, State, county, municipal or other governing authorities, departments, commissions, agencies and boards regarding the collection, sorting, separation, and recycling of garbage, trash, rubbish
and other refuse (collectively, “trash”); (b) to comply with Landlord’s recycling policy as part of Landlord’s sustainability practices where it may be more stringent than applicable law; (c) to sort and separate its
trash and recycling into such categories as are provided by law or Landlord’s sustainability practices; (d) that each separately sorted category of trash and recycling shall be placed in separate receptacles as directed by Landlord;
(e) that Landlord reserves the right to refuse to collect or accept from Tenant any waste that is not separated and sorted as required by law, and to require Tenant to arrange for such collection of Tenant’s sole cost and expense,
utilizing a contractor satisfactory to Landlord; and (f) that Tenant shall pay all costs, expenses, fines, penalties or damages that may be imposed on Landlord or Tenant by reason of Tenant’s failure to comply with the provisions of this
Section. 
 24.37 Transportation Management. 

24.37.1 Tenant shall fully comply with all present or future legally required programs intended to manage parking, transportation or traffic in
and around the Building, and in connection therewith, Tenant shall take responsible action for the transportation planning and management of all employees located at the Premises by working directly with Landlord, any governmental transportation
management organization or any other transportation-related committees or entities. Such programs may include, without limitation: (i) restrictions on the number of peak-hour vehicle trips generated by Tenant; (ii) increased vehicle
occupancy; (iii) implementation of an in-house ridesharing program and an employee transportation coordinator; (iv) working with employees and any Building or area-wide ridesharing program manager;
(v) instituting employer-sponsored incentives (financial or in-kind) to encourage employees to rideshare; and (vi) utilizing flexible work shifts for employees. 

24.37.2 Pursuant to the Conditions of Approval for this project a draft Transportation Demand Management Plan was adopted by the South San
Francisco City Council in October 2006. A final Transportation Demand Management Plan is under development that satisfies the requirement of the City of South San Francisco’s transportation demand management goals and also the San Mateo County
Transportation Demand Management guidelines. The plan is to be provided to tenants of the Building to participate in a program designed to coordinate commute alternatives. During the term of the Tenant’s tenancy, Landlord agrees to provide
transportation brokerage and commute assistance services, as part of Operating Expenses to assist the Tenant in meeting the transportation needs of its employees. Tenant agrees to cooperate with and assist the Landlord’s transportation
management coordinator (the “Coordinator”), through designation of a responsible employee, to distribute to Tenant’s employees written materials promoting and encouraging the use of public transit and/or ridesharing, and
distribute and return to the Coordinator transportation survey questionnaire forms. Tenant may agree, at its option, to participate in other activities required of Landlord and/or ridesharing by employees in the Building. 

24.38 Approvals. Whenever this Lease requires an approval, consent, determination or judgment by either Landlord or Tenant, unless
another standard is expressly set forth in this Lease, such approval, consent, determination or judgment and any conditions imposed thereby shall be reasonable and shall not be unreasonably withheld or delayed. 

  
 -40- 

 IN WITNESS WHEREOF, Landlord and Tenant have caused this Lease to be executed the day and
date first above written. 
  

			
	“Landlord”:
	
	AP3-sF2 CT SOUTH, LLC,
	A Delaware limited liability company
		
	By:	 	 /s/ W. Neil Fox III

	Name:	 	W. Neil Fox III
	Its:	 	CEO
	
	“Tenant”:
	
	APPLIED MOLECULAR TRANSPORT INC.,
	a Delaware corporation
		
	By:	 	 /s/ Tahir Mahmood

		 	Name: Tahir Mahmood
		 	Its: President and Chief Executive Officer
		
	By:	 	  

		 	Name:                                     
                                         
   
		 	Its:                                     
                                         
        

  

	***	 If Tenant is a CORPORATION, the authorized officers must sign on behalf of the corporation and indicate the
capacity in which they are signing. The Lease must be executed by the president or vice president and the secretary or assistant secretary, unless the bylaws or a resolution of the board of directors shall otherwise provide, in which event, the
bylaws or a certified copy of the resolution, as the case may be, must be attached to this Lease. 

  
 -41- 

 EXHIBIT A 

OUTLINE OF FLOOR PLAN OF PREMISES 

[Schematics] 
  

 
  
  

 
  

  

					
		  	EXHIBIT A	  	GENEIS SSF – ONE TOWER PLACE
		  	-1-	  	[Applied Molecular Transport, Inc.]

 EXHIBIT A-1 

SITE PLAN OF PROJECT 

[Schematics] 
  

 
  
  

 

  

					
		  	EXHIBIT A-1	  	GENEIS SSF – ONE TOWER PLACE
		  	-2-	  	[Applied Molecular Transport, Inc.]

 EXHIBIT B 

TENANT WORK LETTER 

This Tenant Work Letter (“Tenant Work Letter”) sets forth the terms and conditions relating to the construction of
improvements for the Premises. All references in this Tenant Work Letter to the “Lease” shall mean the relevant portions of the Lease to which this Tenant Work Letter is attached as Exhibit B. 

SECTION 1 

BASE, SHELL AND CORE 

Landlord has previously constructed the base, shell and core (i) of the Premises and (ii) of the floor(s) of the Building on which
the Premises are located (collectively, the “Base, Shell and Core”), and Tenant shall accept the Base, Shell and Core in its current “As-Is” condition existing as of the date of the
Lease and the Lease Commencement Date. Except as otherwise provided below, Landlord shall not be obligated to make or pay for any alterations or improvements to the Premises, the Building or the Project. 

SECTION 2 

CONSTRUCTION DRAWINGS FOR THE PREMISES 

Prior to the execution of the Lease, Landlord and Tenant have approved a detailed space plan for the construction of certain improvements in
the Premises, which space plan has been prepared by McFarlane Architects, dated December 8, 2016 (the “Final Space Plan”), which Final Space Plan is attached hereto as Schedule 1. Also attached as part of Schedule
1 is a design and construction schedule and an assumptions regarding the design and construction of the Tenant Improvements. Based upon and in conformity with the Final Space Plan, Landlord shall cause its architect and engineers to prepare and
deliver to Tenant, for Tenant’s approval, detailed specifications and engineered working drawings for the tenant improvements shown on the Final Space Plan (the “Working Drawings”). The Working Drawings shall incorporate
modifications to the Final Space Plan as necessary to comply with the floor load and other structural and system requirements of the Building. To the extent that the finishes and specifications are not completely set forth in the Final Space Plan
for any portion of the tenant improvements depicted thereon, the actual specifications and finish work shall be in accordance with the specifications for the Building’s standard tenant improvement items, as set forth in Schedule 2. Within two
(2) business days after Tenant’s receipt of the Working Drawings, Tenant shall approve or disapprove the same, which approval shall not be unreasonably withheld; provided, however, that Tenant may only disapprove the Working Drawings to
the extent such Working Drawings are inconsistent with the Final Space Plan and only if Tenant delivers to Landlord, within such two (2) business day period, specific changes proposed by Tenant which are consistent with the Final Space Plan and
do not constitute changes which would result in any of the circumstances described in items (i) through (iv) hereinbelow. If any such revisions are timely and properly proposed by Tenant, Landlord shall cause its architect and engineers to
revise the Working Drawings to incorporate such revisions and submit the same for Tenant’s approval in accordance with the foregoing provisions, and the parties shall follow the foregoing procedures for approving the Working Drawings until the
same are finally approved by Landlord and Tenant. Upon Landlord’s and Tenant’s approval of the Working Drawings, the same shall be known as the “Approved Working Drawings”. The tenant improvements shown on the Approved
Working Drawings shall be referred to herein as the “Tenant Improvements”. Once the Approved Working Drawings have been approved by Landlord and Tenant, Tenant shall make no changes, change orders or modifications thereto without
the prior written consent of Landlord, which consent may be withheld in Landlord’s sole discretion if such change or modification would: (i) delay the Substantial Completion of the Premises (as defined below) unless Tenant agrees (in
writing) that such delay in the amount specified by Landlord is a Tenant Delay; (ii) increase the costs of the design, permitting and construction of the Tenant Improvements above the costs of the design, permitting and construction of those
tenant improvements depicted in the Final Space Plan; unless Tenant agrees (in writing) to pay such increase in the amount specified by Landlord (iii) be of a quality lower than the quality of the standard tenant improvement items for the
Building; and/or (iv) require any changes to the Base, Shell and Core or structural improvements or systems of the Building. The Final Space Plan, Working Drawings and Approved Working Drawings shall be collectively referred to herein as, the
“Construction Drawings”. 

  

					
		  	EXHIBIT B	  	
		  	-1-	  	

 SECTION 3 

CONSTRUCTION AND PAYMENT FOR COSTS OF TENANT IMPROVEMENTS 

Landlord and Tenant hereby agree that Landlord shall, at Landlord’s expense (except as provided in this Section 3) cause a general
contractor designated by Landlord (the “Contractor”) to (i) obtain all applicable building permits for construction of the Tenant Improvements (collectively, the “Permits”), and (ii) construct the Tenant
Improvements as depicted on the Approved Working Drawings, in compliance with such building permits and all applicable laws in effect at the time of construction, and in good workmanlike manner; provided, however, if Tenant shall request any changes
or substitutions to any of the Construction Drawings, and such differences, changes and/or substitutions result in increased costs of the design, permitting and construction of the Tenant Improvements in excess of the costs of the design, permitting
and construction of those tenant improvements depicted on the Final Space Plan, then Tenant shall pay such excess costs as specified by Landlord at the time such changes are approved (which shall include a Landlord’s supervision fee of four
percent (4%) of such costs) to Landlord in cash within ten (10) days after Landlord’s request therefor. Notwithstanding the foregoing to the contrary, in no event shall Landlord be obligated to pay for the costs of any of Tenant’s
furniture, computer systems, telephone systems, equipment or other personal property which may be depicted on the Construction Drawings; the costs of such items shall be paid for by Tenant from Tenant’s own funds. 

SECTION 4 

READY FOR OCCUPANCY; 

SUBSTANTIAL COMPLETION OF THE TENANT IMPROVEMENTS 

4.1 Ready for Occupancy; Substantial Completion. For purposes of the Lease, including for purposes of determining the Lease
Commencement Date (as set forth in Section 7.2 of the Summary); (i) the Premises shall be “Ready for Occupancy” upon Substantial Completion of the Premises and delivery of the Premises to Tenant in good, vacant, broom clean
condition, with all Systems and Equipment serving the Premises in good operating condition, in compliance with law; and (ii) “Substantial Completion of the Premises” shall occur upon (x) the completion of construction of the
Tenant Improvements in the Premises pursuant to the Approved Working Drawings and Landlord’s Work in compliance with law, with the exception of any punch list items that do not materially and adversely affect Tenant’s use and occupancy of
the Premises and any tenant fixtures, work-stations, built-in furniture, or equipment to be installed by Tenant or under the supervision of the Contractor and (y) the issuance of a temporary certificate
of occupancy or its functional equivalent from the applicable governmental authority for Landlord’s Work and the Tenant Improvements; provided, however, that the cold room portion of the Tenant Improvements may, without affecting the occurrence
of the Lease Commencement Date, be installed by Landlord within forty-five (45) days after the Lease Commencement Date. 
 4.2 Delay
of the Substantial Completion of the Premises. If there shall be a delay or there are delays in the Substantial Completion of the Premises as a result of any of the following (collectively, “Tenant Delays”): 

4.2.1 Tenant’s failure to timely approve the Working Drawings or any other matter requiring Tenant’s approval; 

4.2.2 a breach by Tenant of the terms of this Tenant Work Letter or the Lease; 

4.2.3 Tenant’s request for changes in any of the Construction Drawings in the amount of the delay actually incurred by Landlord on account
of such change but only if the same actually delays Substantial Completion of the Premises; 
 4.2.4 Tenant’s requirement for materials,
components, finishes or improvements which are not available in a commercially reasonable time given the estimated date of Substantial Completion of the Premises, as set forth in the Lease, or which are different from, or not included in,
Landlord’s standard tenant improvement items for the Building in the amount of delay actually incurred by Landlord on account of such change but only if the same actually delays Substantial Completion of the Premises; or 

  

					
		  	EXHIBIT B	  	
		  	-2-	  	

 4.2.5 any other acts or omissions of Tenant, or its agents, or employees that continue more
than one (1) day after written notice thereof by Landlord. 
 then, notwithstanding anything to the contrary set forth in the Lease and regardless of
the actual date of Substantial Completion of the Premises, the Lease Commencement Date (as set forth in Section 7.2 of the Summary) shall be deemed to be the date the Lease Commencement Date would have occurred if no Tenant Delays, as set forth
above, had occurred. Landlord shall deliver to Tenant at the time Landlord approves a request by Tenant pursuant to Sections 4.2.3 or 4.2.4 above, a reasonable, good faith estimate of any delay in Substantial Completion that will result from the
change after consultation with the Contractor. In connection therewith, Landlord shall endeavor to obtain a change order from the Contractor with a specified amount of such delay and, if it is able to obtain such specified amount, Landlord shall
notify Tenant thereof, at the time it approves the request and the amount of Tenant Delay shall not exceed such amount. 
 SECTION 5

 MISCELLANEOUS 

5.1 Tenant’s Entry Into the Premises Prior to Substantial Completion. Subject to the terms hereof and provided that Tenant and its
agents do not interfere with the Contractor’s work in the Project, the Building and the Premises, Landlord shall allow Tenant access to the Premises not less than fifteen (15) days prior to the anticipated Substantial Completion of the
Premises for the purpose of Tenant installing equipment and/or fixtures (including Tenant’s data and telephone equipment) and Tenant’s furniture in the Premises. Prior to Tenant’s entry into the Premises as permitted by the terms of
this Section 5.1, Tenant shall submit a schedule to Landlord and the Contractor, for their approval, which schedule shall detail the timing and purpose of Tenant’s entry. In connection with any such entry, Tenant acknowledges and agrees
that Tenant’s employees, agents, contractors, consultants, workmen, mechanics, suppliers and invitees shall fully cooperate, work in harmony and not, in any manner, interfere with Landlord or Landlord’s contractors (including the
Contractor), agents or representatives in performing work in the Project, the Building and the Premises, or interfere with the general operation of the Building and/or the Project. If at any time any such person representing Tenant shall not be
cooperative or shall otherwise cause or threaten to cause any such disharmony or interference, including, without limitation, labor disharmony, and Tenant fails to immediately institute and maintain corrective actions as directed by Landlord, then
Landlord may revoke Tenant’s entry rights upon twenty-four (24) hours’ prior written notice to Tenant. Tenant acknowledges and agrees that any such entry into and occupancy of the Premises or any portion thereof by Tenant or any
person or entity working for or on behalf of Tenant shall be deemed to be subject to all of the terms, covenants, conditions and provisions of the Lease, excluding only the covenant to pay Rent (until the occurrence of the Lease Commencement Date).
Such requirements shall include, without limitation, that Tenant and any other parties allowed access to the Premises shall provide Landlord with evidence of insurance as required by Landlord. Tenant further acknowledges and agrees that Landlord
shall not be liable for any injury, loss or damage which may occur to any of Tenant’s work made in or about the Premises in connection with such entry or to any property placed therein prior to the Lease Commencement Date, the same being at
Tenant’s sole risk and liability. Tenant shall be liable to Landlord for any damage to any portion of the Premises, including the Tenant Improvement work, caused by Tenant or any of Tenant’s employees, agents, contractors, consultants,
workmen, mechanics, suppliers and invitees. If the performance of Tenant’s work in connection with such entry causes extra costs to be incurred by Landlord or requires the use of any Building services, and Landlord promptly delivers Tenant
written notice thereof, Tenant shall promptly reimburse Landlord for such extra costs and/or shall pay Landlord for such Building services at Landlord’s standard rates then in effect. In addition, Tenant shall hold Landlord harmless from and
indemnify, protect and defend Landlord against any loss or damage to the Premises or Project and against injury to any persons caused by Tenant’s actions pursuant to this Section 5.1. 

5.2 Tenant’s Representative. Tenant has designated Tahir Mahmood as its sole representative with respect to the matters set forth
in this Tenant Work Letter, who shall have full authority and responsibility to act on behalf of the Tenant as required in this Tenant Work Letter. 

5.3 Landlord’s Representative. Landlord has designated BJ Van Aken as its sole representative with respect to the matters set forth
in this Tenant Work Letter, who, until further notice to Tenant, shall have full authority and responsibility to act on behalf of the Landlord as required in this Tenant Work Letter. 

  

					
		  	EXHIBIT B	  	
		  	-3-	  	

 5.4 Time of the Essence in This Tenant Work Letter. Unless otherwise indicated, all
references herein to a “number of days” shall mean and refer to calendar days. If any item requiring approval is timely disapproved by Landlord, the procedure for preparation of the document and approval thereof shall be repeated until the
document is approved by Landlord. Both Landlord and Tenant shall use commercially reasonable, good faith, efforts and all due diligence to cooperate with each other to complete all phases of the Construction Drawings and the permitting process and
to receive the permits, as soon as possible after the execution of the Lease, and, in that regard, shall meet on a scheduled basis to be determined by Landlord and Tenant, to discuss progress in connection with the same. 

5.5 Tenant’s Lease Default. Notwithstanding any provision to the contrary contained in the Lease, if an event of default by Tenant
of this Tenant Work Letter or the Lease has occurred at any time on or before the Substantial Completion of the Premises and remains after the expiration of applicable notice and cure periods, then (i) in addition to all other rights and
remedies granted to Landlord pursuant to the Lease, at law and/or in equity, Landlord shall have the right to cause the Contractor to suspend the construction of the Premises (in which case, Tenant shall be responsible for any delay in the
Substantial Completion of the Premises caused by such work stoppage as a Tenant Delay as set forth in Section 4.2 above), and (ii) all other obligations of Landlord under the terms of this Tenant Work Letter shall be forgiven until such
time as such default is cured pursuant to the terms of the Lease (in which case, Tenant shall be responsible for any delay in the Substantial Completion of the Premises caused by such inaction by Landlord as a Tenant Delay). In addition, if the
Lease is terminated prior to the Lease Commencement Date, for any reason due to a default by Tenant as described in Section 19.1 of the Lease or under this Tenant Work Letter, in addition to any other remedies available to Landlord under the
Lease, at law and/or in equity, Tenant shall pay to Landlord, as Additional Rent under the Lease, within five (5) business days after Tenant’s receipt of a statement therefor, any and all costs incurred by Landlord and not reimbursed or
otherwise paid by Tenant through the date of such termination in connection with the Tenant Improvements to the extent planned, installed and/or constructed as of such date of termination, including, but not limited to, any costs related to the
removal of all or any portion of the Tenant Improvements and restoration costs related thereto. 

  

					
		  	EXHIBIT B	  	
		  	-4-	  	

 SCHEDULE 1 

FINAL SPACE PLAN 

[Schematics] 
  

 
  
  

 

  

					
		  	SCHEDULE 1	  	GENEIS SSF – ONE TOWER PLACE
		  	-1-	  	[Applied Molecular Transport, Inc.]

 

 

  

					
		  	SCHEDULE 1	  	
		  	-2-	  	

 

 

  

					
		  	SCHEDULE 1	  	
		  	-3-	  	

 

 

  

					
		  	SCHEDULE 1	  	
		  	-4-	  	

 

 

  

					
		  	SCHEDULE 1	  	
		  	-5-	  	

 

 

  

					
		  	SCHEDULE 1	  	
		  	-6-	  	

 

 
 Document: 
  

	 	1.	 12/8/2016 AMT -Genesis Towers- Eighth Level Concept Floor Plan, McFarlane Architect 

 

	 	2.	 12/9/16 Constnatioa Schedule, XL-1B Construction 

 

	 	3.	 Equipment List - ‘Needed equipment with Volts and Amps info’, sent 12/9/16, New Mark

  

	 	4.	 Email correspondence from
12-9-16 starting with drawing transmission listed above. 

Clarifications 
 General Assumptions 

 

	 	1.	 All work for this project is included to be performed during standard SSF bows, Monday thru Friday 7-0, with the exception of scopes on the 2nd floor 

  

	 	2.	 Construction phasing is not included. 

 

	 	3.	 Utility Connection charges and fees and usage fees are excluded: gas power, water, sewer, telephone, cable,
etc. 

  

	 	4.	 Builders Risk Insurance is by phase 3. 

 

	 	5.	 We assume onsite parking, trailers, and laydown for the duration of construction in our pricing.

  

	 	6.	 General Conditions are added as required for the contract scope. The team is part of an overall team whose
allocation and size is dependent on the total volume of work. Allocation and staff volum will be evaluated by XL-1B and Phase 3 regularly. 

 

	 	7.	 We can restructure as desired but currently the pricing assumes plan check and permit costs are by phase 3.

  

	 	8.	 No allowances are carried in this budget 

 

	 	9.	 Tenant signage is carried by Phase 3. XL includes TCO required signage only. 

 

	 	10.	 Special inspection fees are not carried in XL’s budget. Please carry them on the owner side.

  

	 	11.	 LIED certifications can be provided for additional costs. 

 

	 	12.	 BIM and 3D coordination and/or models and as-boats can be provided for
an additional cost. 

  

	 	13.	 Cold box will not be available for the March 24, 2017 TCO. Efforts will be made to find time savings and
to look into prefabricated solutions that may save time, however it is not anticipated. XL-113 requires performance specs for the Cold Box by 12/15/16 to meet the published schedule. 

Site and Structure 
  

	 	14.	 No additional stiffening is provided as part of this budget. Only the area over the loading dock and new 2nd
floor mechanical room will be stiffened (base warm up scope) 

 Architectural Trades and Finishes 

 

	 	15.	 Assume VCT in all lab areas with the exception of epoxy in the Autoclave room and welded coved sheet vinyl in
the Tissue autism suite WCT in the microscope room) 

  

	 	16.	 ACT ceilings everywhere 1as in spec) with the exception of a drywall ceiling in the Autoclave room

  

	 	17.	 Walls between conference and reception areas and adjacent spaces are to be full height 

 

	 	18.	 Casework to be dabs. 

 

	 	19.	 U/C cabinets to math dashed lines shown on 12-8 plan. Assumes 15 door
and drawer cabinets and 15 3-drawer cabinets 

  

	 	20.	 No millwork in the copy room 

 

	 	21.	 Office and conference room doors are stain grade with KD aluminum frames. 

  

					
		  	    	  	
		  	-7-	  	

 Mechanical Electrical Plumbing and Fire Sprinklers 

 

	 	22.	 includes 12) 6-foot constant volume fume hoods with normal power, house
vac and CDA. 

  

	 	23.	 includes CDA and Vac distribution to all casework benches alone with 3
20-AMP circuits (1 e-power and 2 normal) 

  

	 	24.	 Power for equipment based on Equipment list provided 12/9. All equipment on list assumed to have a single point
of connection for power. Other than drain for the ice maker, no specialty utilities (other than CDA and VAC) are included. 

  

	 	25.	 Includes an Allowance for the Cold Box. Covers box construction and design, fabrication, mechanical systems,
controls, condensate, curbs, etc. If price of cold room package exceeds allowance, cost increase is responsibility of Phase 3. If costs of CR package is less than allowance, a credit will be provided. 

 

	 	26.	 Includes one water source heat pump for the tenant. 

 

	 	27.	 All equipment BSCs, Vac Pumps, Incubators, Glasswashers, Autoclaves, Fermentors, etc, are lab equipment
furnished by the tenant. 

  

	 	28.	 All DI water (if needed), He, and Air systems are by future tenant and NIC. 

 

	 	29.	 No HEPA filtration is included anywhere. 

 

	 	30.	 Revised MEP coordination effort impacts have not been started at this time. Gross modifications to the MEP
overhead. 

  

	 	31.	 Freezers are assumed on E-power. 

  

					
		  	    	  	
		  	-8-	  	

 SCHEDULE 2 

BUILDING STANDARD IMPROVEMENTS 

Genesis South 
 1
Tower Place, 
 South San Francisco, CA 94080 

Tenant Improvement Building Standards 
  

	1.0	 PARTITIONS 

  

	 	1.1	 DEMISING WALL - ONE HOUR FIRE RESISTIVE CONSTRUCTION 

One Hour Fire Resistive Wall will be constructed to demise tenant spaces with 3 5/8” x 20 gauge metal studs at 16” O.C. Wall is to
extend full height from floor to underside of structure above with 5/8” Type “X” gypsum wallboard on each side of studs. Gypsum wallboard shall be taped and finished with joint compound to a Level 4 finish, with the stud cavity
filled with sound attenuation insulation to achieve a minimum STC of 49. 
  

	 	1.2	 INTERIOR PARTITIONS 

Interior partitions will be constructed with 3 5/8” x 20 gauge metal studs at 16” O.C. Walls are to extend 6” above adjacent
ceilings with 5/8” gypsum wallboard placed on each side of studs. Gypsum wallboard shall be taped and finished with joint compound to a Level 4 finish, with the stud cavity being filled with sound attenuation insulation in partitions
between offices and conference rooms. Where no ceilings occur, partitions to extend full height to underside of structure above. 
  

	2.0	 WOOD DOORS AND FRAMES 

 

	 	2.1	 SUITE ENTRY DOORS 

 

	 	2.1.1	 Main suite entry doors (if main entry is from elev. lobby) are to be 60 minute rated, 1 3/4” x 3’-0” x 8’-0” Solid core, plain sliced walnut, finish: Marshfield Doors clear 0-95 or equivalent.

  

	 	2.1.2	 Other suite entry doors are to be 60 minute rated, 1 3/4” x
3’-0” x 8’-0” Solid core, plain sliced walnut, finish: Marshfield Doors clear 0-95 or equivalent.

  

	 	2.2	 INTERIOR DOORS 

 

	 	2.2.1	 Office and Conference Room Doors are to be 1 3/4” x
3’-0” x 8’-0” solid core, plain sliced walnut, finish: Marshfield Doors clear 0-95 or equivalent.

  

	 	2.2.2	 Common Area and Support Room Doors are to be 1 3/4” x
3’-0” x 8’-0” solid core, plain sliced walnut, finish: Marshfield Doors clear 0-95 or equivalent.

  

	 	2.2.3	 Laboratory Doors are to be 60 minute rated where required, non-rated
elsewhere, 1 3/4” x 3’-0” x 8’-0”. Solid core, plain sliced walnut, finish: Marshfield Doors clear
0-95 or equivalent. Each lab will have a pair of doors for large equipment access. Doors are to be a half-lite vision panel consisting of 1/4” thick tempered safety glass. Armor plates and kick plates
will be provided on Lab doors at appropriate locations. 

  

	 	2.2.4	 Lab Support Doors, where provided, are to be 60 minute rated as required,
non-rated elsewhere, 1 3/4” x 3’-6” x 8’-0”. Solid core, plain sliced walnut, finish: Marshfield
Doors clear 0-95 or equivalent. Doors are to be a half-lite vision panel consisting of 1/4” thick tempered safety glass. Armor plates and kick plates will be provided on Lab Support Doors at
appropriate locations. 

  

					
		  	SCHEDULE 2	  	
		  	-1-	  	

	 	2.3	 DOOR/WINDOW FRAMES 

 

	 	2.3.1	 Door frames will be extruded aluminum alloy as manufactured by Western Integrated Materials Inc. Frames will be
pre-punched for factory installed 14 gauge butt reinforcement, door strike, and closer hardware. Prefinished frame color to be: Clear anodized aluminum. 

 

	 	2.3.2	 Rated doors and frames shall be as required by code, with label ratings for smoke and fire resistance meeting
the requirements established by the Underwriters Laboratory (UL). Doors will include smoke seals. Door frames will be extruded aluminum alloy as manufactured by Western Integrated Materials Inc. Frames will be
pre-punched for factory installed 14 gauge butt reinforcement, door strike, and closer hardware. Prefinished frame color to be: Clear anodized aluminum. 

 

	 	2.4	 FINISH HARDWARE 

 

	 	2.4.1	 SUITE ENTRY 

For solid core wood doors: 

Hinges: 4-1/2” X 4-1/2” Hager AB700 Full Mortise
Hinge, Finish: ANSI A8112 
 steel with steel pin. 

Office entry lock set: Mortise Lever Schlage L Series, L9453 03A, Finish: 625 

Closers: Yale 
 One wall bumper:
Hager 236W, Finish: US26D Chromium plated, dull. 
  

	 	2.4.2	 INTERIOR DOORS 

For solid core wood doors: 

Hinges: 4-1/2” X 4-1/2” Hagar AB700 Full Mortise
Hinge, Finish: ANSI A8112 
 Steel with steel pin 

Passage Set: Schlage L Series Mortise L9010 03A Finish: 625 

One wall bumper: Hager 236W, Finish: US26D Chromium plated dull 
  

	3.0	 CEILINGS 

  

	 	3.1	 ACOUSTICAL CEILINGS 

Ceilings will be 2” x 2” x 3/4” Armstrong, Ultima Tegular Fine Texture, Color: White. Glass-fiber based panels to be Type IV
mineral based with membrane-faced overlay; form 2, water felted with vinyl overlay on face and back of panel. Performance characteristics to meet the following: 

a. LR: Not less than 0.90. 
 b.
NRC: Not less than 0.70. 
 Acoustical panels are treated with manufacturer’s standard antimicrobial formulation that inhibits
fungus, mold, mildew, and gram-positive and gram-negative bacteria.  
 Suspension system: Armstrong Silhouette Narrow 9/16”
with 1/4” reveal; Color: White.  
  

	 	3.2	 VINYL-FACED CEILINGS 

Ceilings will be 2” x 4” x 1/2” Certainteed Saint-Gobain, Vinylrock (#1140 CRF-1),
Color: White. Vinyl-faced panels shall be Type XX; high density, ceramic and mineral base panels with scrubbable finish, resistant to heat, moisture, and corrosive fumes.  

Suspension system: Certainteed Saint-Gobain 15/16” trim edge (square); Color: White 

  

					
		  	    SCHEDULE 2	  	
		  	-2-	  	

	 	3.3	 GYPSUM WALLBOARD SOFFITS-SUITE LOBBY AND BREAK AREA 

Gypsum wallboard soffits will be constructed with 3 5/8” x 20 gauge metal studs at 16” O.C., with 5/8” gypsum wallboard placed
on exterior side of studs. Gypsum wallboard shall be taped and finished with joint compound to a Level 4 finish. Soffits 
  

	4.0	 LIGHTING FIXTURES 

 

	 	4.1	 Office and Lab area light fixtures shall be min. 6” wide recessed linear LED type by Finelite or
equivalent. 

  

	 	4.2	 Lab Support rooms shall have recessed 2’x4’ LED troffers.  

 

	 	4.3	 All lighting shall have Title 24 compliant lighting controls and sensors.  

 

	5.0	 ELECTRICAL SWITCHES AND OUTLET COVER PLATES 

 

	 	5.1	 Electrical cover plates shall be Decora Leviton #5325, Color: white. 

 

	 	5.2	 Motion sensor Light switch and cover plates shall be Advanced Central Technologies Color: White.

  

	 	5.3	 Light Switch Decora Leviton #5601 

 

	6.0	 FINISHES 

  

	 	6.1	 CARPET 

  

	 	a.	 Manufacturers: Tandus-Centiva or architect’s approved equivalent 

 

	 	b.	 Product Size: 6’ Roll Power-bond or 24” x 24” carpet tile  

 

	 	c.	 Backing: Per manufacturer’s recommendation  

 

	 	d.	 Face Weight: 20 oz./sq. yd.  

 

	 	e.	 Pile Height Average: 0.187 inch  

 

	 	f.	 Fiber System: Dynex SD Nylon (Permanent Stain Resistance)  

 

	 	g.	 Soil/Stain Protection: Ensure  

 

	 	6.2	 CERAMIC TILE 

  

	 	a.	 Manufacturers: 

 

	 	1.	 Fiandre 

  

	 	2.	 Ergon  

  

	 	3.	 Emil Ceramica  

 

	 	4.	 American Olean  

 

	 	5.	 Or architect approved equivalent 

 

	 	b.	 Composition: Vitreous or impervious natural clay or porcelain  

 

	 	c.	 Face Size: Per Drawings  

 

	 	d.	 Face Size Variation: Calibrated or rectified  

 

	 	e.	 Thickness: Manufacturers standard  

 

	 	f.	 Dynamic Coefficient of Friction: Not less than 0.42.  

 

	 	g.	 Trim Units: Coordinated with sizes and coursing of adjoining flat tile where applicable and matching
characteristics of adjoining flat tile. Architect to select from manufacturer’s full range. 

  

	 	6.3	 VINYL COMPOSITION TILE 

 

	 	a.	 Manufacturers: 

  

	 	1.	 Armstrong World Industries, Inc. 

 

	 	2.	 Johnsonite (Tarkett Group) 

  

					
		  	SCHEDULE 2	  	
		  	-3-	  	

	 	3.	 Mannington Commercial 

 

	 	b.	 Tile Standard: ASTM F 1066, Class 1, solid-color 

 

	 	c.	 Thickness: 0.125 inches 

 

	 	d.	 Size: 12 by 12 inches 

 

	 	6.4	 LUXURY VINYL TILE 

 

	 	a.	 Manufacturers: 

  

	 	1.	 Tandus-Centiva  

 

	 	2.	 Johnsonite (Tarkett Group)  

 

	 	3.	 Mannington Commercial  

 

	 	b.	 b. Tile Standard: ASTM F 1700, Class 3, Type B 

 

	 	c.	 c. Thickness: 0.100 to 0.120 inches 

 

	 	d.	 d. Size: As indicated on drawings 

 

	 	6.5	 BASE 

  

	 	a.	 Manufacturers: 

  

	 	1.	 Armstrong World Industries, Inc. 

 

	 	2.	 Johnsonite (Tarkett Group)  

 

	 	3.	 VPI Corporation  

 

	 	b.	 Product Standard: ASTM F 1861, Type TP (rubber, thermoplastic). 

 

	 	1.	 Group: I (solid, homogeneous). 

 

	 	2.	 Style and Location: As indicated. 

 

	 	c.	 Thickness: 0.125 inch 

 

	 	d.	 Height: 4” high 

 

	 	e.	 Lengths: Coils in manufacturer’s standard length. Pre-cut lengths
are not acceptable. 

  

	 	f.	 Outside Corners: Job formed or preformed. 

 

	 	g.	 Inside Corners: Job formed or preformed. 

 

	 	6.6	 PAINT 

All walls will receive (2) coats of Sherwin Williams, Eggshell Finish; Color: As indicated on drawings. Designated walls shall receive
accent paints, choice of Sherwin Williams, Eggshell Finish, Color: As indicated on drawings. 
 All ceilings and open to structure areas to
receive (2) coats of Sherwin Williams, Flat Finish; Color: As indicated on drawings. 
  

	7.0	 WINDOW TREATMENT 

 

	 	7.1	 Exterior Window Shades, where provided, will be manual-type roller shades by Mechoshade in recessed factory
housing. Shade Material shall be Thermoveil 1500, Color: 1504 Black/Brown; Density: 3% Open. 

  

	8.0	 MISCELLANEOUS 

 

	 	8.1	 SIGNAGE 

One building standard suite number and name plaque per entry door. Restroom signage. 

 

	 	8.2	 ILLUMINATED EXIT SIGNS 

Lithonia (or Isolite equal) ceiling mounted illuminated Edge Lit Series with single face universal mount, with universal
arrows & green letters. 

  

					
		  	SCHEDULE 2	  	
		  	-4-	  	

	9.0	 ELECTRICAL 

  

	 	9.1	 Tenant shall receive building standard 120V 20 amp electrical distribution to office areas of the suite from
the building’s main electrical room. Each office will have (2) duplex electrical outlets and (2) mud box with ring and string for tenants own tel/data installation. Labs will receive standards 120V power and specialty voltage power as
required for lab equipment. 

  

	10.0	 HVAC 

  

	 	10.1	 Heating and Cooling will be provided by a heating hot water boiler and a cooling tower, all placed on the roof.

  

	 	10.2	 Air Handling to the labs will be provided by new packaged units supplying 100% outside air with new VAV supply
and exhaust boxes with minimum of 8 air changes per hour. 

  

	 	10.3	 Air handling to the office areas will be provided by existing packaged units with new VAV supply boxes.

  

	11.0	 11.0 BREAKROOM CABINETRY WITH PLUMBING 

 

	 	11.1	 Tenant allowance is 6 lineal feet of plastic laminate base cabinet with 6” drawers and doors, with 6
lineal feet of 12” deep by 36” high upper cabinets with doors. Sink is to be single bowl stainless steel, top mount, 6 1/2 “max deep, 20 gauge, with a single lever faucet Moen Chateau 7425. Plastic laminated base and uppers:
Wilsonart, Designer white #D354-01 (gloss finish). Provide PVC edge banding (0.018 to match plastic laminate) Solid surface counter tops and splash: Livingstone L104 Brisk. 

 

	12.0	 LABORATORY CASEWORK AND FUME HOODS 

 

	 	12.1	 Casework: Labs will be furnished with modular, mobile metal laboratory casework manufactured by iLab, Inc.
Countertops will be chemical resistant epoxy/phenolic resin. Island benches shall be pre-piped for Compressed Air and Lab Vacuum with quick disconnect connections located above the ceiling. Benches with sinks
will have a single basin epoxy sink (21” x 15” x 10” deep). Sink cabinets shall have a hot and cold water mixing faucet with a counter mounted eyewash. Sinks at island benches will have a stainless steel glassware pegboard with drip
tray and drain hose. Benches will be pre-wired with factory installed single channel raceways for power. Receptacles will be GFI and color coded for normal (grey) and emergency (red) power uses.

  

	 	12.2	 Fume Hoods: Fume Hoods will be 6’ wide, bench top hoods with a combination sash. Hoods will be factory pre-piped and pre-wired for Vacuum, Compressed Air and normal power with all services on each fume hood post. Hoods shall be UL 1805 listed and provide a minimum of 100 FPM
exhaust with the sash in any position. Hoods will also be provided with self-closing acid and flammable storage cabinet bases. 

NOTES: 
  

	 	1.	 Each prospective build-out, including but not limited to electrical,
mechanical and plumbing design shall be reviewed and verified prior to commencement of Construction Documents and is subject to Landlord’s review and approval. 

 

	 	2.	 Upgraded items beyond Building Standards include, but are not limited to, the following: 

 

	 	1.	 Cabinetry beyond 6 lineal feet standard 

 

	 	2.	 Upgraded Carpet. 

  

	 	3.	 Interior Windows (beyond approved side light window) 

  

					
		  	SCHEDULE 2	  	
		  	-5-	  	

	 	4.	 Gypsum Board Ceilings 

 

	 	5.	 Plumbing, beyond single bowl standard 

 

	 	6.	 Architectural Features (i.e. Light Soffit, Curved Walls, etc., not shown on spec plan) 

 

	 	7.	 Wallcoverings 

  

	 	8.	 Dedicated or Higher Voltage Electrical Outlets 

 

	 	9.	 24 Hour Cooling 

  

	 	10.	 Interior design and drawings for above noted upgrades 

 

	 	11.	 Customized lab design 

 

	 	3.	 The following items are responsibility of the Tenant and are excluded from the Owner’s scope of work to be
provided: 

  

	 	1.	 Security/Access Control within the Tenant Suite. 

 

	 	2.	 Signage beyond Code required egress signage. 

 

	 	3.	 Audio/Visual systems 

 

	 	4.	 Data distribution within the Tenant Suite 

 

	 	5.	 Server Room HVAC / Dedicated system 

 

	 	6.	 UPS systems for Tenant Equipment. 

  

					
		  	SCHEDULE 2	  	
		  	-6-	  	

 EXHIBIT B-1 

LANDLORD’S WORK 
 In
addition to the Tenant Improvements described in the Tenant Work Letter attached to the Lease as Exhibit B, prior to the Commencement Date Landlord shall construct the improvements, described below, in
the Building (“Landlord’s Work”), which shall be constructed utilizing Building-standard materials and finishes consistent with the balance of the Project, as determined by Landlord in its sole discretion. Tenant may not change
or alter the Landlord’s Work. 
  

	 	•	 	 Installation of one (1) service elevator with access up to floor 7 

 

	 	•	 	 Installation of new 1,250 KW generator and main standby power distribution to floors 3-8 

  

	 	•	 	 Installation of new AHU’s to support standard office and lab
build-out on floors 3-8 

  

	 	•	 	 Installation of new heating hot water boiler and pumps 

 

	 	•	 	 Installation of new exhaust fans on floors 3-8 to support standard office
and lab improvements 

  

	 	•	 	 Installation of plumbing infrastructure to include vacuum system and compressed air with risers to floors 3-8 

  

	 	•	 	 Upgrade existing cooling tower to support standard lab improvements throughout the Building

  

	 	•	 	 On-floor restroom facilities 

  

					
		  	EXHIBIT B-1	  	
		  	-1-	  	

 EXHIBIT C 

CONFIRMATION OF LEASE TERMS/AMENDMENT TO LEASE 

This CONFIRMATION OF LEASE TERMS/AMENDMENT TO LEASE (“Confirmation/Amendment”) is made and entered into effective as of
__________________, 20__, by and between AP3-SF2 CT SOUTH, LLC, a Delaware limited liability company (“Landlord”) and ____________, a __________ (“Tenant”). 

R E C I T A L S: 

A. Landlord and Tenant entered into that certain Lease dated as of __________________ (the “Lease”) pursuant to which
Landlord leased to Tenant and Tenant leased from Landlord certain “Premises”, as described in the Lease, in that certain building located at _____________, ____________, California ______. 

B. Except as otherwise set forth herein, all capitalized terms used in this Amendment shall have the same meaning as such terms have in the
Lease. 
 C. Landlord and Tenant desire to amend the Lease to confirm the commencement and expiration dates of the term, as hereinafter
provided. 
 NOW, THEREFORE, in consideration of the foregoing Recitals and the mutual covenants contained herein, and for other good and
valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto agree as follows: 
 1.
Confirmation of Dates. The parties hereby confirm that (a) the Premises are Ready for Occupancy, and (b) the term of the Lease commenced as of ___________________ for a term of __________________ ending on ________________ (unless
sooner terminated as provided in the Lease. Tenant shall commence to pay rent on _________________, 20__ (“Rent Commencement Date”). 

2. No Further Modification. Except as set forth in this Amendment, all of the terms and provisions of the Lease shall remain
unmodified and in full force and effect. 

  

					
		  	EXHIBIT C	  	
		  	-1-	  	

 IN WITNESS WHEREOF, this Amendment has been executed as of the day and year first above
written. 
  

					
	“Landlord”:
	
	AP3-SF2 CT SOUTH, LLC,
	a Delaware limited liability company
		
	By:	 	
                 

	Name:	 	          

	Its:	 	          

	
	“Tenant”:
	
	  

 
					
	a	 	  

 
					
		
	By:	 	              

		 	Name:	 	              

		 	Its:	 	              

		
	By:	 	              

		 	Name:	 	              

		 	Its:	 	          

  

					
		  	EXHIBIT C	  	
		  	-2-	  	

 EXHIBIT D 

RULES AND REGULATIONS 

Tenant shall faithfully observe and comply with the following Rules and Regulations and the Parking Rules and Regulations. Landlord shall not
be responsible to Tenant for the nonperformance of any of said Rules and Regulations and/or the Parking Rules and Regulations by or otherwise with respect to the acts or omissions of any other tenants or occupants of the Building and/or the Project.

 1. Tenant shall not place any lock(s) on any door, or install any security system (including, without limitation, card key systems, alarms
or security cameras), in the Premises without Landlord’s prior written consent, which consent shall not be unreasonably withheld, and Landlord shall have the right to retain at all times and to use keys or other access codes or devices to all
locks and/or security systems within and to the Premises. A reasonable number of keys to the locks on the entry doors of the Premises shall be furnished by Landlord to Tenant at Tenant’s cost, and Tenant shall not make any duplicate keys. All
keys shall be returned to Landlord at the expiration or earlier termination of the Lease. Further, if and to the extent Tenant re-keys, re-programs or otherwise changes
any locks in or for the Premises, all such locks and key systems must be consistent with the master lock and key system at the Building, all at Tenant’s sole cost and expense. 

2. All doors opening to public corridors shall be kept closed at all times except for normal ingress and egress to the Premises, unless
electrical hold backs have been installed. Sidewalks, doorways, passages, entrances, vestibules, halls, stairways and other Common Areas shall not be obstructed by Tenant or used by Tenant for any purpose other than ingress and egress to and from
the Premises, and Tenant, its employees and agents shall not loiter in the entrances or corridors. 
 3. Landlord reserves the right to close
and keep locked all entrance and exit doors of the Building during such hours as are customary for comparable buildings in the vicinity of the Building. Tenant and its employees and agents shall ensure that the doors to the Building are securely
closed and locked when leaving the Premises if it is after the normal hours of business for the Building. Any tenant, its employees, agents or any other persons entering or leaving the Building at any time when it is so locked, or any time when it
is considered to be after normal business hours for the Building, may be required to sign the Building register when so doing. After-hours access by Tenant’s authorized employees may be provided by
hard-key, card-key access or other procedures adopted by Landlord from time to time; Tenant shall pay for the costs of all access cards provided to Tenant’s
employees and all replacements thereof for lost, stolen and/or damaged cards. Access to the Building and/or the Project may be refused unless the person seeking access has proper identification or has a previously arranged pass for such access.
Landlord and its agents shall in no case be liable for damages for any error with regard to the admission to or exclusion from the Building and/or the Project of any person. In case of invasion, mob, riot, public excitement, or other commotion,
Landlord reserves the right to prevent access to the Building and/or the Project during the continuance of same by any means it deems appropriate for the safety and protection of life and property. 

4. Landlord shall have the right to prescribe the weight, size and position of all safes and other heavy property brought into the Building.
Safes and other heavy objects shall, if considered necessary by Landlord, stand on supports of such thickness as is necessary to properly distribute the weight. Landlord will not be responsible for loss of or damage to any such safe or property in
any case. All damage done to any part of the Building, its contents, occupants and/or visitors by moving or maintaining any such safe or other property shall be the sole responsibility of Tenant and any expense of said damage or injury shall be
borne by Tenant. 
 5. No furniture, freight, packages, supplies, equipment or merchandise will be brought into or removed from the Building
or carried up or down in the elevators, except upon prior notice to Landlord, and in such manner, in such specific elevator, and between such hours as shall be designated by Landlord. Tenant shall provide Landlord with not less than 24 hours’
prior notice of the need to utilize an elevator for any such purpose, so as to provide Landlord with a reasonable period to schedule such use and to install such padding or take such other actions or prescribe such procedures as are appropriate to
protect against damage to the elevators or other parts of the Building. Tenant shall assume all risk for damage to articles moved and injury to any persons resulting from such activity described herein. If equipment, property, or personnel of
Landlord or of any other party is damaged or injured as a result of or in connection with such activity described herein, Tenant shall be solely liable for any resulting damage or loss. 

  

					
		  	EXHIBIT D	  	
		  	-1-	  	

 6. Landlord shall have the right to control and operate the public portions of the Building
and Project, the public facilities, the heating and air conditioning, and any other facilities furnished for the common use of tenants, in such manner as is customary for comparable buildings in the vicinity of the Building. 

7. No signs, advertisements or notices shall be painted or affixed to windows, doors or other parts of the Building, except those of such
color, size, style and in such places as are first approved in writing by Landlord. Landlord shall have the right to remove any signs, advertisements, and notices not approved in writing by Landlord without notice to and at the expense of Tenant.
Landlord may provide and maintain in the first floor (main lobby) of the Building an alphabetical directory board or other directory device listing tenants, and no other directory shall be permitted unless previously consented to by Landlord in
writing. 
 8. The requirements of Tenant will be attended to only upon application at the management office of the Project or at such office
location designated by Landlord. Employees of Landlord shall not perform any work or do anything outside their regular duties unless under special instruction from Landlord. 

9. Tenant shall not disturb (by use of any television, radio or musical instrument, making loud or disruptive noises, creating offensive odors
or otherwise), solicit, or canvass any occupant of the Building and/or the Project and shall cooperate with Landlord or Landlord’s agents to prevent same. 

10. The toilet rooms, urinals, wash bowls and other apparatus shall not be used for any purpose other than that for which they were
constructed, and no foreign substance of any kind whatsoever shall be thrown therein. The expense of any breakage, stoppage or damage resulting from the violation of this rule shall be borne by the tenant who, or whose employees or invitees, shall
have caused it. 
 11. Tenant shall not overload the floor of the Premises. Tenant shall not mark, drive nails or screws, or drill into the
partitions, woodwork or plaster or in any way deface the Premises or any part thereof without Landlord’s consent first had and obtained; provided, however, Landlord’s prior consent shall not be required with respect to Tenant’s
placement of pictures and other normal office wall hangings on the interior walls of the Premises (but at the end of the Lease Term, Tenant shall repair any holes and other damage to the Premises resulting therefrom). 

12. Except for vending machines intended for the sole use of Tenant’s employees and invitees, no vending machine or machines of any
description other than fractional horsepower office machines shall be installed, maintained or operated upon the Premises without the written consent of Landlord. Tenant shall not install, operate or maintain in the Premises or in any other area of
the Building, electrical equipment that would overload the electrical system beyond its capacity for proper, efficient and safe operation as determined solely by Landlord. 

13. Tenant shall not use any method of heating or air conditioning other than that which may be supplied by Landlord, without the prior written
consent of Landlord. Tenant shall not furnish cooling or heating to the Premises, including, without limitation, the use of electronic or gas heating devices, portable coolers (such as “move n cools”) or space heaters, without
Landlord’s prior written consent, and any such approval will be for devices that meet federal, state and local code. 
 14. No
inflammable, explosive or dangerous fluids or substances shall be used or kept by Tenant in the Premises, Building and/or about the Project, except for those substances as are typically found in similar premises used for general office and/or
laboratory purposes and are being used by Tenant in a safe manner and in accordance with all applicable Laws, rules and regulations. Tenant shall not, without Landlord’s prior written consent, use, store, install, spill, remove, release or
dispose of, within or about the Premises or any other portion of the Project, any asbestos-containing materials or any solid, liquid or gaseous material now or subsequently considered toxic or hazardous under the provisions of 42 U.S.C.
Section 9601 et seq. or any other applicable environmental Laws which may now or later be in effect. Tenant shall comply with all Laws pertaining to and governing the use of these materials by Tenant, and shall remain solely liable for the
costs of abatement and removal. 

  

					
		  	EXHIBIT D	  	
		  	-2-	  	

 15. Tenant shall not use, keep or permit to be used or kept, any foul or noxious gas or
substance in or on the Premises, or permit or allow the Premises to be occupied or used in a manner offensive or objectionable to Landlord or other occupants of the Building and/or the Project by reason of noise, odors, or vibrations, or interfere
in any way with other tenants or those having business therewith. 
 16. Tenant shall not bring into or keep within the Project, the Building
or the Premises any animals (except those assisting handicapped persons), birds, fish tanks, bicycles or other vehicles. 
 17. Tenant shall
not use or occupy the Premises in any manner or for any purpose which might injure the reputation or impair the present or future value of the Premises, the Building and/or the Project. Tenant shall not use, or permit any part of the Premises to be
used, for lodging, sleeping or for any illegal purpose. 
 18. No cooking shall be done or permitted by Tenant on the Premises, nor shall the
Premises be used for the storage of merchandise or for any improper, objectionable or immoral purposes. Notwithstanding the foregoing, Underwriters’ laboratory-approved equipment and microwave ovens may be used in the Premises for heating food
and brewing coffee, tea, hot chocolate and similar beverages, provided that such use is in accordance with all applicable federal, state and city laws, codes, ordinances, rules and regulations, and does not cause odors which are objectionable to
Landlord and other tenants. Whenever possible, Tenant shall utilize and purchase Energy Star products in their suites. Tenant understands the importance of energy conservation and sustainability to both the Landlord and the Project, and will assist
in conserving energy in their suite with regards to practices and equipment. 
 19. Landlord will approve where and how telephone and
telegraph wires and other cabling are to be introduced to the Premises. No boring or cutting for wires shall be allowed without the consent of Landlord. The location of telephone, call boxes and other office equipment and/or systems affixed to the
Premises shall be subject to the approval of Landlord. Tenant shall not use more than its proportionate share of telephone lines and other telecommunication facilities available to service the Building. 

20. Landlord reserves the right to exclude or expel from the Building and/or the Project any person who, in the judgment of Landlord, is
intoxicated or under the influence of liquor or drugs, or who shall in any manner do any act in violation of any of these Rules and Regulations or cause harm to Building occupants and/or property. 

21. All contractors, contractor’s representatives and installation technicians performing work in the Building or at the Project shall be
subject to Landlord’s prior approval, which approval shall not be unreasonably withheld, and shall be required to comply with Landlord’s standard rules, regulations, policies and procedures, which may be revised from time to time. 

22. Tenant shall not employ any person other than the janitor of Landlord for the purpose of cleaning the Premises without prior written
consent of Landlord, and without Landlord’s consent, no person or persons shall be permitted to enter the Building for the purpose of cleaning the same. Tenant shall not cause any unnecessary labor by reason of Tenant’s carelessness or
indifference in the preservation of good order and cleanliness. 
 23. Tenant shall only employ persons from a list of exclusive vendors
selected by Landlord for the removal of hazardous waste materials from the Building and the Project 24. Tenant at all times shall maintain the entire Premises in a neat and clean, first class condition, free of debris. Tenant shall not place items,
including, without limitation, any boxes, files, trash receptacles or loose cabling or wiring, in or near any window to the Premises which would be visible anywhere from the exterior of the Premises. 

24. Tenant shall not waste electricity, water or air conditioning and agrees to cooperate fully with Landlord to ensure the most effective
operation of the Building’s heating and air conditioning system, including, without limitation, the use of window blinds to block solar heat load, and shall refrain from attempting to adjust any controls. Tenant shall comply with and
participate in any program for metering or otherwise measuring the use of utilities and services, including, without limitation, programs requiring the disclosure or reporting of the use of any utilities or services. Tenant shall also cooperate and
comply with, participate in, and assist in the implementation of (and take no action that is inconsistent with, or which would result in Landlord, the Building and/or the Project failing to comply with the requirements of) any conservation,
sustainability, recycling, energy efficiency, and waste reduction 

  

					
		  	EXHIBIT D	  	
		  	-3-	  	

 
programs, environmental protection efforts and/or other programs that are in place and/or implemented from time to time at the Building and/or the Project, including, without limitation, any
required reporting, disclosure, rating or compliance system or program (including, but not limited to, any LEED [Leadership in Energy and Environmental Design] rating or compliance system, including those currently coordinated through the U.S. Green
Building Council). 
 25. Tenant shall store all its recyclables, trash and garbage within the interior of the Premises. No material shall be
placed in the trash boxes or receptacles if such material is of such nature that it may not be disposed of in the ordinary and customary manner of removing and disposing of recyclables, trash and garbage in the city in which the Project is located
without violation of any law or ordinance governing such disposal. All trash, garbage and refuse disposal shall be made only through entry-ways and elevators provided for such purposes at such times as Landlord shall designate. 

26. Tenant shall comply with all safety, fire protection and evacuation procedures and regulations established by Landlord or any governmental
agency. 
 27. Tenant shall assume any and all responsibility for protecting the Premises from theft, robbery and pilferage, which includes
keeping doors locked and other means of entry to the Premises closed, when the Premises are not occupied, or when the entry to the Premises is not manned by Tenant on a regular basis. 

28. No awnings or other projection shall be attached to the outside walls of the Building without the prior written consent of Landlord. No
curtains, blinds, shades or screens shall be attached to or hung in, or used in connection with, any window or door of the Premises without the prior written consent of Landlord. The sashes, sash doors, skylights, windows, and doors that reflect or
admit light and air into the halls, passageways or other public places in the Building shall not be covered or obstructed by Tenant, nor shall any bottles, parcels or other articles be placed on the windowsills. All electrical ceiling fixtures hung
in offices or spaces along the perimeter of the Building must be fluorescent and/or of a quality, type, design and bulb color approved by Landlord. 

29. The washing and/or detailing of or, the installation of windshields, radios, telephones in or general work on, automobiles shall not be
allowed on the Project, except under specific arrangement with Landlord. 
 30. Food vendors shall be allowed in the Building upon receipt of
a written request from Tenant delivered to Landlord. The food vendor shall service only the tenants that have a written request on file in the management office of the Project. Under no circumstance shall the food vendor display their products in a
public or Common Area including corridors and elevator lobbies. Any failure to comply with this rule shall result in immediate permanent withdrawal of the vendor from the Building. Tenant shall obtain ice, drinking water, linen, barbering, shoe
polishing, floor polishing, cleaning, janitorial, plant care or other similar services only from vendors who have registered in the management office of the Project and who have been approved by Landlord for provision of such services in the
Premises. 
 31. Tenant must comply with requests by the Landlord concerning the informing of their employees of items of importance to the
Landlord. 
 32. Tenant shall comply with any non-smoking ordinance adopted by any applicable
governmental authority. Neither Tenant nor its agents, employees, contractors, guests or invitees shall smoke or permit smoking in the Premises and/or the Common Areas, unless the Common Areas have been declared a designated smoking area by
Landlord, nor shall the above parties allow smoke from the Premises to emanate into the Common Areas or any other part of the Building. Landlord shall have the right to designate the Building (including the Premises) as a non-smoking building. 
 33. Tenant shall not take any action which would violate Landlord’s labor
contracts or which would cause a work stoppage, picketing, labor disruption or dispute, or interfere with Landlord’s or any other tenant’s or occupant’s business or with the rights and privileges of any person lawfully in the Building
(“Labor Disruption”). Tenant shall take the actions necessary to resolve the Labor Disruption, and shall have pickets removed and, at the request of Landlord, immediately terminate any work in the Premises that gave rise to the Labor
Disruption, until Landlord gives its written consent for the work to resume, and Tenant shall have no claim for damages against Landlord or any of its trustees, members, principals, beneficiaries, partners, officers, directors, employees,
mortgagees, or agents in connection therewith. 

  

					
		  	EXHIBIT D	  	
		  	-4-	  	

 34. No tents, shacks, temporary or permanent structures of any kind shall be allowed on the
Project. No personal belongings may be left unattended in any Common Areas. 
 35. Landlord shall have the right to prohibit the use of the
name of the Building or Project or any other publicity by Tenant that in Landlord’s sole opinion may impair the reputation of the Building or Project or the desirability thereof. Upon written notice from Landlord, Tenant shall refrain from and
discontinue such publicity immediately. 
 36. Landlord shall have the right to designate and approve standard window coverings for the
Premises and to establish rules to assure that the Building presents a uniform exterior appearance. Tenant shall ensure, to the extent reasonably practicable, that window coverings are closed on windows in the Premises while they are exposed to the
direct rays of the sun. 
 37. The work of cleaning personnel shall not be hindered by Tenant after 5:30 P.M., and cleaning work may be done
at any time when the offices are vacant. Windows, doors and fixtures may be cleaned at any time. Tenant shall provide adequate waste and rubbish receptacles to prevent unreasonable hardship to the cleaning service. 

38. Tenant shall comply with all Building security procedures as Landlord may effectuate. 

39. Tenant shall at all times cooperate with Landlord in preserving a first-class image for the Building. 

PARKING RULES AND REGULATIONS 

1. Landlord reserves the right to establish and reasonably change the hours for the Parking Facility, on a
non-discriminatory basis, from time to time. Tenant shall not store or permit its employees to store any automobiles in the Parking Facility without the prior written consent of Landlord (and/or the Parking
Operator, as the case may be). Except for emergency repairs, Tenant and its employees shall not perform any work on any automobiles while located in the Parking Facility or on the Project. The Parking Facility may not be used by Tenant or its agents
for overnight parking of vehicles. If it is necessary for Tenant or its employees to leave an automobile in the Parking Facility overnight, Tenant shall provide Landlord (or the Parking Operator as the case may be) with prior notice thereof
designating the license plate number and model of such automobile. 
 2. Tenant (including Tenant’s employees and agents) will use the
parking spaces solely for the purpose of parking passenger model cars, small vans and small trucks and will comply in all respects with any rules and regulations that may be promulgated by Landlord and/or the Parking Operator from time to time with
respect to the Parking Facility. 
 3. Vehicles must be parked entirely within the stall lines painted on the floor, and only small cars may
be parked in areas reserved for small cars. 
 4. All directional signs and arrows must be observed. 

5. The speed limit shall be 5 miles per hour. 

6. Parking spaces reserved for handicapped persons must be used only by vehicles properly designated. 

7. Parking is prohibited in all areas not expressly designated for parking, including without limitation: 

(a) areas not striped for parking; 

(b) aisles; 
 (c) where “no
parking” signs are posted; 
 (d) ramps; and 

(e) loading zones. 

  

					
		  	EXHIBIT D	  	
		  	-5-	  	

 8. Parking stickers, key cards and any other devices or forms of identification or entry
supplied by Landlord or the Parking Operator shall remain the property of Landlord (or the Parking Operator as the case may be). Such device must be displayed as requested and may not be mutilated in any manner. The serial number of the parking
identification device may not be obliterated. Parking passes and devices are not transferable and any pass or device in the possession of an unauthorized holder will be void. 

9. Parking managers or attendants are not authorized to make or allow any exceptions to these Parking Rules and Regulations. 

10. Every parker is required to park and lock his/her own car. 

11. Loss or theft of parking passes, identification, key cards or other such devices must be reported to Landlord (and/or to the Parking
Operator as the case may be) immediately. Any parking devices reported lost or stolen found on any authorized car will be confiscated and the illegal holder will be subject to prosecution. Lost or stolen passes and devices found by Tenant or its
employees must be reported to Landlord (and to the Parking Operator, as the case may be) immediately. 
 12. Washing, waxing, cleaning or
servicing of any vehicle by the customer and/or its agents is prohibited. 
 13. Tenant agrees to acquaint all persons to whom Tenant assigns
a parking space with these Parking Rules and Regulations. 
 14. Neither Landlord nor the Parking Operator (as the case may be), from time to
time will be liable for loss of or damage to any vehicle or any contents of such vehicle or accessories to any such vehicle, or any property left in any of the Parking Facility, resulting from fire, theft, vandalism, accident, conduct of other users
of the Parking Facility and other persons, or any other casualty or cause. Further, Tenant understands and agrees that: (i) Landlord will not be obligated to provide any traffic control, security protection or Parking Operator for the Parking
Facility; (ii) Tenant uses the Parking Facility at its own risk; and (iii) Landlord will not be liable for personal injury or death, or theft, loss of or damage to property. Tenant indemnifies and agrees to hold Landlord, any Parking
Operator and their respective agents and employees harmless from and against any and all claims, demands, and actions arising out of the use of the Parking Facility by Tenant and its employees and agents, whether brought by any of such persons or
any other person. 
 15. Tenant will ensure that any vehicle parked in any of the parking spaces will be kept in proper repair and will not
leak excessive amounts of oil or grease or any amount of gasoline. If any of the parking spaces are at any time used (i) for any purpose other than parking as provided above, (ii) in any way or manner reasonably objectionable to Landlord,
or (iii) by Tenant after default by Tenant under the Lease, Landlord, in addition to any other rights otherwise available to Landlord, may consider such default an event of default under the Lease. 

16. Tenant’s right to use the Parking Facility will be in common with other tenants of the Building and with other parties permitted by
Landlord to use the Parking Facility. Landlord reserves the right to assign and reassign, from time to time, particular parking spaces for use by persons selected by Landlord, provided that Tenant’s rights under the Lease are preserved.
Landlord will not be liable to Tenant for any unavailability of Tenant’s designated spaces, if any, nor will any unavailability entitle Tenant to any refund, deduction, or allowance. Tenant will not park in any numbered space or any space
designated as: RESERVED, HANDICAPPED, VISITORS ONLY, or LIMITED TIME PARKING (or similar designation). 
 17. If the Parking Facility is
damaged or destroyed, or if the use of the Parking Facility is limited or prohibited by any governmental authority, or the use or operation of the Parking Facility is limited or prevented by strikes or other labor difficulties or other causes beyond
Landlord’s reasonable control, Tenant’s inability to use the parking spaces will not subject Landlord (and/or the Parking Operator, as the case may be) to any liability to Tenant and will not relieve Tenant of any of its obligations under
the Lease and the Lease will remain in full force and effect. Tenant will pay to Landlord upon demand, and Tenant indemnifies Landlord against, any and all loss or damage to the Parking Facility, or any equipment, fixtures, or signs used in
connection with the Parking Facility and any adjoining buildings or structures caused by Tenant or any of its employees and agents. 

  

					
		  	EXHIBIT D	  	
		  	-6-	  	

 18. Tenant has no right to assign or sublicense any of its rights in the parking passes,
except as part of a permitted assignment or sublease of the Lease; however, Tenant may allocate the parking passes among its employees. 

Tenant shall be responsible for the observance of all of the Rules and Regulations and Parking Rules and Regulations in this Exhibit
D by Tenant’s employees, agents, clients, customers, invitees and guests. Landlord may waive any one or more of the Rules and Regulations and/or Parking Rules and Regulations for the benefit of any particular tenant or tenants, but no
such waiver by Landlord shall be construed as a waiver of such Rules and Regulations and/or Parking Rules and Regulations in favor of any other tenant or tenants, nor prevent Landlord from thereafter enforcing any such Rules or Regulations and/or
Parking Rules and Regulations against any or all tenants of the Building and/or the Project. Landlord reserves the right at any time to change or rescind any one or more of these Rules and Regulations and/or the Parking Rules and Regulations, or to
make such other and further reasonable Rules and Regulations and/or Parking Rules and Regulations as in Landlord’s judgment may from time to time be necessary for the management, safety, care and cleanliness of the Premises, Building and
Project, and for the preservation of good order therein, as well as for the convenience of other occupants and tenants therein. Tenant shall be deemed to have read these Rules and Regulations and Parking Rules and Regulations and to have agreed to
abide by them as a condition of its occupancy of the Premises. 
 COMMON AREA AMENITIES 

1. Tenant understands that Landlord may provide certain common area amenities for Tenant’s
non-exclusive use. Such amenities are for the use of tenants during regular business hours and shall be reserved through the management office in advance. Tenant and Tenant’s agents, employees and
invitees shall adhere to all rules Landlord sets forth in respect to use of the amenities, which may change from time to time. 
 2. Tenant
understands and agrees that: (i) Tenant uses the amenities at its own risk; and (ii) Landlord will not be liable for personal injury or death, or theft, loss of or damage to property. Tenant indemnifies and agrees to hold Landlord and its
agents and employees harmless from and against any and all claims, demands, and actions arising out of the use of the amenities by Tenant and its agents, employees and invitees, whether brought by any of such persons or any other person. 

3. All amenities offered shall remain at the locations designated by Landlord all times. Tenant must use the equipment only in the manner
intended. Landlord reserves the right to limit Tenant’s use of any equipment or amenities to ensure the equitable use of the equipment and amenities by all tenants. Tenant shall not move or modify the equipment in any manner whatsoever. If
Tenant has reason to believe that any equipment is malfunctioning, Tenant shall notify Landlord immediately. 
 4. Tenant shall be
responsible for the cost or repairs or replacements of any amenities that are not returned to management after use or are damaged during the use of any such amenity by Tenant or Tenant’s agents, employees or invitees and Tenant shall reimburse
Landlord for any such cost within thirty (30) days after receipt of an invoice therefor. 
 5. Tenant shall conduct themselves in a
quiet and well-mannered fashion when on or about the amenities and not cause any disturbances or interfere with the use or enjoyment of the amenities by other tenants. 

6. Tenant shall not bring any food or beverages into any amenity area. 

7. No alcoholic beverages shall be permitted at the amenities at any time. 

8. Neither Tenant nor its agents, employees or invitees shall smoke or permit smoking in the amenity areas at any time. 

  

					
		  	EXHIBIT D	  	
		  	-7-	  	

 EXHIBIT E 

CONTROL AREAS FOR HAZARDOUS MATERIALS STORAGE 

[Schematics] 
  

 
  
  

 

  

					
		  	EXHIBIT E	  	GENEIS SSF – ONE TOWER PLACE
		  	-1-	  	[Applied Molecular Transport, Inc.]

 EXHIBIT F 

GENERAL STORAGE AREA 

[Schematics] 
  

 
  
  

 

  

					
		  	EXHIBIT F	  	GENEIS SSF – ONE TOWER PLACE
		  	-1-	  	[Applied Molecular Transport, Inc.]

 RIDER 

EXTENSION OPTION RIDER 

This Extension Option Rider (“Extension Rider”) is attached to and made a part of the Lease by and between Landlord and
Tenant. The agreements set forth in this Extension Rider shall have the same force and effect as if set forth in the Lease. To the extent the terms of this Extension Rider are inconsistent with the terms of the Lease, the terms of this Extension
Rider shall control. 
 1. Extension Options. Landlord hereby grants Tenant two (2) options (each, an “Extension
Option”) to extend the then current Lease Term for a period of three (3) years (the “Option Term”), which option shall be exercisable only by written Exercise Notice (as defined below) delivered by Tenant to Landlord
as provided below. Upon the proper exercise of any such Extension Option, the Lease Term shall be extended for the applicable Option Term. Notwithstanding the foregoing, at Landlord’s option, in addition to any other remedies available to
Landlord under the Lease, at law or in equity, the Extension Option shall not be deemed properly exercised if as of the date of delivery of the Exercise Notice (as defined below) by Tenant, Tenant has previously been in default under the Lease
beyond all applicable notice and cure periods in the preceding twelve (12) month period (as those terms are defined below). The Extension Option is personal to the original Tenant and may only be exercised by the Original Tenant and any
Affiliate Assignee (and not any other assignee, sublessee or other transferee of Tenant’s interest in the Lease). 
 2. Option
Rent. The annual Base Rent payable by Tenant during the applicable Option Term (the “Option Rent”) shall be equal to the greater of: (i) the annual Base Rent payable by Tenant during the last year of the then current Lease
Term; or (ii) the Fair Market Rental Rate for comparable office/laboratory space in the South San Francisco market. As used herein, the “Fair Market Rental Rate” shall mean the annual base rent at which tenants, as of the
commencement of the applicable Option Term, will be leasing non-sublease space comparable in size, location (including views) and quality to the Premises for a comparable term as the applicable Option Term,
which comparable space is located in the Building, the Other Existing Building in the Project and in other comparable first-class biotechnology buildings in San Mateo County, taking into consideration all free rent and other out-of-pocket concessions generally being granted at such time for such comparable space for the applicable Option Term (including, without limitation, any tenant improvement
allowance provided for such comparable space and that Tenant will not be receiving such concessions). All other terms and conditions of the Lease shall apply throughout the applicable Option Term; however, Tenant shall, in no event, have the option
to extend the Lease Term beyond the applicable two (2) Option Terms described in Section 1 above. 
 3. Exercise of Options.
The Extension Option shall be exercised by Tenant, if at all, only in the following manner: (i) Tenant shall deliver written notice (“Interest Notice”) to Landlord not more than fifteen (15) months nor less than fourteen
(14) months prior to the expiration of the initial Lease Term stating that Tenant may be interested in exercising the Extension Option; (ii) Landlord, after receipt of Tenant’s notice, shall deliver notice (the “Option Rent
Notice”) to Tenant not less than thirteen (13) months prior to the expiration of the then current Lease Term setting forth the Option Rent; and (iii) if Tenant wishes to exercise the applicable Extension Option, Tenant shall, on
or before the date (the “Exercise Date”) which is (12) months prior to the expiration of the then current Lease Term, exercise the applicable Extension Option by delivering written notice (“Exercise Notice”)
thereof to Landlord. Tenant’s failure to deliver the Interest Notice or Exercise Notice on or before the applicable delivery dates therefore specified hereinabove shall be deemed to constitute Tenant’s waiver of the applicable Extension
Option and such Extension Option and any succeeding Extension Option shall be null and void and of no further force or effect. 
 4.
Determination of Option Rent. If Tenant timely and appropriately objects in its Exercise Notice to Landlord to the Fair Market Rental Rate for the Option Term initially determined by Landlord, then Landlord and Tenant shall attempt in good
faith to agree upon the Fair Market Rental Rate. If Landlord and Tenant fail to reach agreement within thirty (30) days following Tenant’s delivery of such Exercise Notice (the “Outside Agreement Date”), then each party
shall submit to the other party a separate written determination of the Fair Market Rental Rate within fifteen (15) business days after the Outside Agreement Date, and such determinations shall be submitted to arbitration in accordance with the
provisions of Sections 4.1 through 4.6 below; provided, however, Landlord shall not submit an amount in excess of the set forth in the Option Rent Notice. The failure of Tenant or Landlord to submit a written determination of the Fair Market Rental
Rate within such fifteen (15) business day period shall conclusively be deemed to be such party’s approval of the Fair Market Rental Rate submitted within such fifteen (15) business day period by the other party. 

  

					
		  	RIDER	  	
		  	-1-	  	

 4.1 Landlord and Tenant shall each appoint one (1) arbitrator who shall by profession
be an independent real estate broker who shall have no ongoing relationship with Tenant or Landlord and who shall have been active over the five (5) year period ending on the date of such appointment in the leasing of first biotechnology office
buildings in the Market Area. The determination of the arbitrators shall be limited solely to the issue of whether Landlord’s or Tenant’s submitted Fair Market Rental Rate is the closer to the actual Fair Market Rental Rate as determined
by the arbitrators, taking into account the requirements with respect thereto set forth in Section 2 above. Each such arbitrator shall be appointed within fifteen (15) days after the Outside Agreement Date. 

4.2 The two (2) arbitrators so appointed shall, within fifteen (15) days of the date of the appointment of the last appointed
arbitrator, agree upon and appoint a third arbitrator who shall be qualified under the same criteria set forth hereinabove for qualification of the initial two (2) arbitrators. 

4.3 The three (3) arbitrators shall, within thirty (30) days of the appointment of the third arbitrator, reach a decision as to which
of Landlord’s or Tenant’s submitted Fair Market Rental Rate is closer to the actual Fair Market Rental Rate and shall select such closer determination as the Fair Market Rental Rate and notify Landlord and Tenant thereof. 

4.4 The decision of the majority of the three (3) arbitrators shall be binding upon Landlord and Tenant. 

4.5 If either Landlord or Tenant fails to appoint an arbitrator within the time period specified in Section 4.1 hereinabove, the
arbitrator appointed by one of them shall reach a decision, notify Landlord and Tenant thereof, and such arbitrator’s decision shall be binding upon Landlord and Tenant. 

4.6 If the two (2) arbitrators fail to agree upon and appoint a third arbitrator, within the time period provided in Section 4.2
above, then the parties shall mutually select the third arbitrator. If Landlord and Tenant are unable to agree upon the third arbitrator within ten (10) days after the fifteen (15) day period described in Section 4.2 above, then
either party may, upon at least five (5) days’ prior written notice to the other party, request the Presiding Judge of the San Mateo County Superior Court, acting in his private and nonjudicial capacity, to appoint the third arbitrator.
Following the appointment of the third arbitrator, the panel of arbitrators shall within thirty (30) days thereafter reach a decision as to whether Landlord’s or Tenant’s submitted Fair Market Rental Rate shall be used and shall
notify Landlord and Tenant thereof. 

  

					
		  	RIDER	  	
		  	-2-Exhibit 4.3

       

       

       

       

       

       

       

       

       

      
        

        
 

      

      

      

      

      

      

      

      

      EURONAV NV

      

      FORM OF

      

      

      SENIOR INDENTURE

      

      

      Dated as of [           ], 20[ ]

      

      

      

      

      

      

      

      

      [                        ]

      

      

      Trustee

      

      

      

      

      

      

      
        

        
 

      

      

      

      
        
          
            
 

        

      

      

      TABLE OF CONTENTS

       

       

       

      
        
          
            	 	
                     

                  
	 	 
	
                    ARTICLE I DEFINITIONS AND INCORPORATION BY REFERENCE

                  	
                    1

                  

          

           

          	
                  SECTION 1.01.

                	
                  Definitions.

                	
                  1

                
	
                  SECTION 1.02.

                	
                  Other Definitions.

                	
                  5

                
	
                  SECTION 1.03.

                	
                  Incorporation by Reference of Trust Indenture Act.

                	
                  5

                
	
                  SECTION 1.04.

                	
                  Rules of Construction.

                	
                  6

                

           

          	
                  ARTICLE II THE SECURITIES

                	
                  6

                

           

          	
                  SECTION 2.01.

                	
                  Issuable in Series.

                	
                  6

                
	
                  SECTION 2.02.

                	
                  Establishment of Terms of Series of Securities.

                	
                  7

                
	
                  SECTION 2.03.

                	
                  Execution and Authentication.

                	
                  9

                
	
                  SECTION 2.04.

                	
                  Registrar and Paying Agent.

                	
                  10

                
	
                  SECTION 2.05.

                	
                  Paying Agent to Hold Money in Trust.

                	
                  10

                
	
                  SECTION 2.06.

                	
                  Securityholder Lists.

                	
                  11

                
	
                  SECTION 2.07.

                	
                  Transfer and Exchange.

                	
                  11

                
	
                  SECTION 2.08.

                	
                  Mutilated, Destroyed, Lost and Stolen Securities.

                	
                  12

                
	
                  SECTION 2.09.

                	
                  Outstanding Securities.

                	
                  12

                
	
                  SECTION 2.10.

                	
                  Treasury Securities.

                	
                  13

                
	
                  SECTION 2.11.

                	
                  Temporary Securities.

                	
                  13

                
	
                  SECTION 2.12.

                	
                  Cancellation.

                	
                  13

                
	
                  SECTION 2.13.

                	
                  Defaulted Interest.

                	
                  14

                
	
                  SECTION 2.14.

                	
                  Global Securities.

                	
                  14

                
	
                  SECTION 2.15.

                	
                  CUSIP Numbers.

                	
                  16

                

           

          	
                  ARTICLE III REDEMPTION

                	
                  16

                

           

          	
                  SECTION 3.01.

                	
                  Notice to Trustee.

                	
                  16

                
	
                  SECTION 3.02.

                	
                  Selection of Securities to be Redeemed.

                	
                  16

                
	
                  SECTION 3.03.

                	
                  Notice of Redemption.

                	
                  17

                
	
                  SECTION 3.04.

                	
                  Effect of Notice of Redemption.

                	
                  17

                
	
                  SECTION 3.05.

                	
                  Deposit of Redemption Price.

                	
                  18

                
	
                  SECTION 3.06.

                	
                  Securities Redeemed in Part.

                	
                  18

                

           

           

           

          
            
              
                
 

            

          

           

           

          
            	
                    ARTICLE IV COVENANTS

                  	
                    18

                  

             

            	
                    SECTION 4.01.

                  	
                    Payment of Principal and Interest.

                  	
                    18

                  
	
                    SECTION 4.02.

                  	
                    SEC Reports.

                  	
                    18

                  
	
                    SECTION 4.03.

                  	
                    Compliance Certificate.

                  	
                    19

                  
	
                    SECTION 4.04.

                  	
                    Stay, Extension and Usury Laws.

                  	
                    20

                  
	
                    SECTION 4.05.

                  	
                    Corporate Existence.

                  	
                    20

                  
	
                    SECTION 4.06.

                  	
                    Taxes.

                  	
                    20

                  
	
                    SECTION 4.07.

                  	
                    Additional Interest Notice.

                  	
                    20

                  
	
                    SECTION 4.08.

                  	
                    Further Instruments and Acts.

                  	
                    20

                  

             

            	
                    ARTICLE V SUCCESSORS

                  	
                    21

                  

             

            	
                    SECTION 5.01.

                  	
                    When Company May Merge, Etc.

                  	
                    21

                  
	
                    SECTION 5.02.

                  	
                    Successor Corporation Substituted.

                  	
                    21

                  

             

            	
                    ARTICLE VI DEFAULTS AND REMEDIES

                  	
                    21

                  

             

            	
                    SECTION 6.01.

                  	
                    Events of Default.

                  	
                    21

                  
	
                    SECTION 6.02.

                  	
                    Acceleration of Maturity; Rescission and Annulment.

                  	
                    23

                  
	
                    SECTION 6.03.

                  	
                    Collection of Indebtedness and Suits for Enforcement by Trustee.

                  	
                    25

                  
	
                    SECTION 6.04.

                  	
                    Trustee May File Proofs of Claim.

                  	
                    25

                  
	
                    SECTION 6.05.

                  	
                    Trustee May Enforce Claims Without Possession of Securities.

                  	
                    26

                  
	
                    SECTION 6.06.

                  	
                    Application of Money Collected.

                  	
                    26

                  
	
                    SECTION 6.07.

                  	
                    Limitation on Suits.

                  	
                    26

                  
	
                    SECTION 6.08.

                  	
                    Unconditional Right of Holders to Receive Principal and Interest.

                  	
                    27

                  
	
                    SECTION 6.09.

                  	
                    Restoration of Rights and Remedies.

                  	
                    27

                  
	
                    SECTION 6.10.

                  	
                    Rights and Remedies Cumulative.

                  	
                    27

                  
	
                    SECTION 6.11.

                  	
                    Delay or Omission Not Waiver.

                  	
                    27

                  
	
                    SECTION 6.12.

                  	
                    Control by Holders.

                  	
                    28

                  
	
                    SECTION 6.13.

                  	
                    Waiver of Past Defaults.

                  	
                    28

                  
	
                    SECTION 6.14.

                  	
                    Undertaking for Costs.

                  	
                    28

                  

             

            	
                    ARTICLE VII TRUSTEE

                  	
                    29

                  

             

            	
                    SECTION 7.01.

                  	
                    Duties of Trustee.

                  	
                    29

                  
	
                    SECTION 7.02.

                  	
                    Rights of Trustee.

                  	
                    30

                  

             

             

             

            
              
                
                  
 

              

            

             

            	
                    SECTION 7.03.

                  	
                    Individual Rights of Trustee.

                  	
                    31

                  
	
                    SECTION 7.04.

                  	
                    Trustee's Disclaimer.

                  	
                    31

                  
	
                    SECTION 7.05.

                  	
                    Notice of Defaults.

                  	
                    31

                  
	
                    SECTION 7.06.

                  	
                    Reports by Trustee to Holders.

                  	
                    31

                  
	
                    SECTION 7.07.

                  	
                    Compensation and Indemnity.

                  	
                    32

                  
	
                    SECTION 7.08.

                  	
                    Replacement of Trustee.

                  	
                    32

                  
	
                    SECTION 7.09.

                  	
                    Successor Trustee by Merger, etc.

                  	
                    33

                  
	
                    SECTION 7.10.

                  	
                    Eligibility; Disqualification.

                  	
                    33

                  
	
                    SECTION 7.11.

                  	
                    Preferential Collection of Claims Against Company.

                  	
                    34

                  

             

            	
                    ARTICLE VIII SATISFACTION AND DISCHARGE; DEFEASANCE

                  	
                    34

                  

             

            	
                    SECTION 8.01.

                  	
                    Satisfaction and Discharge of Indenture.

                  	
                    34

                  
	
                    SECTION 8.02.

                  	
                    Application of Trust Funds; Indemnification.

                  	
                    35

                  
	
                    SECTION 8.03.

                  	
                    Legal Defeasance of Securities of any Series.

                  	
                    36

                  
	
                    SECTION 8.04.

                  	
                    Covenant Defeasance.

                  	
                    37

                  
	
                    SECTION 8.05.

                  	
                    Repayment to Company.

                  	
                    38

                  

             

            	
                    ARTICLE IX AMENDMENTS AND WAIVERS

                  	
                    38

                  

             

            	
                    SECTION 9.01.

                  	
                    Without Consent of Holders.

                  	
                    38

                  
	
                    SECTION 9.02.

                  	
                    With Consent of Holders.

                  	
                    39

                  
	
                    SECTION 9.03.

                  	
                    Limitations.

                  	
                    40

                  
	
                    SECTION 9.04.

                  	
                    Compliance with Trust Indenture Act.

                  	
                    40

                  
	
                    SECTION 9.05.

                  	
                    Revocation and Effect of Consents.

                  	
                    41

                  
	
                    SECTION 9.06.

                  	
                    Notation on or Exchange of Securities.

                  	
                    41

                  
	
                    SECTION 9.07.

                  	
                    Trustee Protected.

                  	
                    41

                  
	
                    SECTION 9.08.

                  	
                    Effect of Supplemental Indenture.

                  	
                    41

                  

             

            	
                    ARTICLE X MISCELLANEOUS

                  	
                    42

                  

             

            	
                    SECTION 10.01.

                  	
                    Trust Indenture Act Controls.

                  	
                    42

                  
	
                    SECTION 10.02.

                  	
                    Notices.

                  	
                    42

                  
	
                    SECTION 10.03.

                  	
                    Communication by Holders with Other Holders.

                  	
                    43

                  
	
                    SECTION 10.04.

                  	
                    Certificate and Opinion as to Conditions Precedent.

                  	
                    43

                  
	
                    SECTION 10.05.

                  	
                    Statements Required in Certificate or Opinion.

                  	
                    43

                  

             

             

            
              
                
                  
 

              

            

             

            
              	
                      SECTION 10.06.

                    	
                      Record Date for Vote or Consent of Holders.

                    	
                      44

                    
	
                      SECTION 10.07.

                    	
                      Rules by Trustee and Agents.

                    	
                      44

                    
	
                      SECTION 10.08.

                    	
                      Legal Holidays.

                    	
                      44

                    
	
                      SECTION 10.09.

                    	
                      No Recourse Against Others.

                    	
                      44

                    
	
                      SECTION 10.10.

                    	
                      Counterparts.

                    	
                      44

                    
	
                      SECTION 10.11.

                    	
                      Governing Laws and Submission to Jurisdiction.

                    	
                      45

                    
	
                      SECTION 10.12.

                    	
                      No Adverse Interpretation of Other Agreements.

                    	
                      45

                    
	
                      SECTION 10.13.

                    	
                      Successors.

                    	
                      45

                    
	
                      SECTION 10.14.

                    	
                      Severability.

                    	
                      45

                    
	
                      SECTION 10.15.

                    	
                      Table of Contents, Headings, Etc.

                    	
                      45

                    
	
                      SECTION 10.16.

                    	
                      Securities in a Foreign Currency or in ECU.

                    	
                      46

                    
	
                      SECTION 10.17.

                    	
                      Judgment Currency.

                    	
                      46

                    
	
                      SECTION 10.18.

                    	
                      Compliance with Applicable Anti-Terrorism and Money Laundering Regulations.

                    	
                      47

                    

               

              	
                      ARTICLE XI SINKING FUNDS

                    	  	
                      47

                    

               

              	
                      SECTION 11.01.

                    	
                      Applicability of Article.

                    	
                      47

                    
	
                      SECTION 11.02.

                    	
                      Satisfaction of Sinking Fund Payments with Securities.

                    	
                      48

                    
	
                      SECTION 11.03.

                    	
                      Redemption of Securities for Sinking Fund.

                    	
                      48

                    

            

          

        

        

        

        

        
          
            
              
 

          

        

        

      

      

      

      Reconciliation and tie between Trust Indenture Act of 1939 and Indenture,

      Dated as of [            ], 20[ ]

       

      
        	
                Section 310(a)(1)

              	
                7.10

              
	
                (a)(2)

              	
                7.10

              
	
                (a)(3)

              	
                Not Applicable

              
	
                (a)(4)

              	
                Not Applicable

              
	
                (a)(5)

              	
                7.10

              
	
                (b)

              	
                7.10

              
	
                (c)

              	
                Not Applicable

              
	
                Section 311(a)

              	
                7.11

              
	
                (b)

              	
                7.11

              
	
                (c)

              	
                Not Applicable

              
	
                Section 312(a)

              	
                2.06

              
	
                (b)

              	
                10.03

              
	
                (c)

              	
                10.03

              
	
                Section 313(a)

              	
                7.06

              
	
                (b)(1)

              	
                7.06

              
	
                (b)(2)

              	
                7.06

              
	
                (c)(1)

              	
                7.06

              
	
                (d)

              	
                7.06

              
	
                Section 314(a)

              	
                4.02, 10.05

              
	
                (b)

              	
                Not Applicable

              
	
                (c)(1)

              	
                10.04

              
	
                (c)(2)

              	
                10.04

              
	
                (c)(3)

              	
                Not Applicable

              
	
                (d)

              	
                Not Applicable

              
	
                (e)

              	
                10.05

              
	
                (f)

              	
                Not Applicable

              
	
                Section 315(a)

              	
                7.01

              
	
                (b)

              	
                7.05

              
	
                (c)

              	
                7.01

              
	
                (d)

              	
                7.01

              
	
                (e)

              	
                6.14

              
	
                Section 316(a)(1)(A)

              	
                6.12

              
	
                (a)(1)(B)

              	
                6.13

              
	
                (a)(2)

              	
                Not Applicable

              
	
                (b)

              	
                6.13

              
	
                (c)

              	
                10.06

              
	
                Section 317(a)(1)

              	
                6.03

              
	
                (a)(2)

              	
                6.04

              
	
                (b)

              	
                2.05

              
	
                Section 318(a)

              	
                10.01

              

      

       

      Note:  This reconciliation and tie shall not, for any purpose, be deemed to be part of the Indenture.

      

      

         

      

      
        
          
            
 

        

      

      

      Indenture dated as of [                        ], 20[ ] between EURONAV NV, a company organized under the laws of Belgium (the
        "Company") and [           ] (the "Trustee").

       

      Each party agrees as follows for the benefit of the other party and for the equal and ratable benefit of the Holders of the Securities
        issued under this Indenture.

       

      ARTICLE I

       

      DEFINITIONS AND INCORPORATION BY REFERENCE

       

      SECTION 1.01.  Definitions.

       

      "Additional Amounts" means any additional amounts which are required hereby or
        by any Security, under circumstances specified herein or therein, to be paid by the Company in respect of certain taxes imposed on Holders specified therein and which are owing to such Holders.

       

      "Affiliate" of any specified person means any other person directly or
        indirectly controlling or controlled by or under direct or indirect common control with such specified person.  For the purposes of this definition, "control" (including, with correlative meanings, the terms "controlled by" and "under common
        control with"), as used with respect to any person, shall mean the possession, directly or indirectly, of the power to direct or cause the direction of the management or policies of such person, whether through the ownership of voting securities or
        by agreement or otherwise.

       

      "Agent" means any Registrar or Paying Agent.

       

      "Bankruptcy Law" means Title 11 of the United States Code (or any successor
        thereto) or any similar federal or state law for the relief of debtors.

       

      "Board of Directors" means the board of directors of the Company or any duly
        authorized committee thereof.

       

      "Board Resolution" means a copy of a resolution certified by the Secretary or
        an Assistant Secretary of the Company to have been adopted by the Board of Directors or pursuant to authorization by the Board of Directors and to be in full force and effect on the date of the certificate and delivered to the Trustee.

       

      "Business Day" means any day other than a (x) Saturday, (y) Sunday or (z) day
        on which state or federally chartered banking institutions in New York, New York are not required to be open.

       

      "Capital Stock" of any Person means any and all shares, interests, rights to
        purchase, warrants, options, participations or other equivalents of or interests in (however designated) equity of such Person, but excluding any debt securities convertible into such equity.

       

      

      
        
          1

          
            
 

        

      

      

      "Certificated Securities" means Securities in the form of physical,
        certificated Securities in registered form.

       

      "Company" means the party named as such above until a successor replaces it in
        accordance with the terms of this Indenture and thereafter means the successor.

       

      "Company Order" means a written order signed in the name of the Company by two
        Officers, one of whom must be the Company's principal executive officer, principal financial officer or principal accounting officer.

       

      "Company Request" means a written request signed in the name of the Company by
        its Chairman of the Board, a President or a Vice President, and by its Chief Financial Officer, its Secretary or an Assistant Secretary, and delivered to the Trustee.

       

      "Corporate Trust Office" means the office of the Trustee at which at any
        particular time its corporate trust business shall be principally administered which office at the date of the execution of this Indenture is [             ], Attention: [              ], or at such other address as the Trustee may designate from
        time to time.

       

      "Custodian" means any receiver, trustee, assignee, liquidator, sequestrator or
        similar official under any Bankruptcy Law.

       

      "Default" or "default" means any event which is, or after notice or passage of
        time or both would be, an Event of Default.

       

      "Default Rate" means the default rate of interest specified in the Securities.

       

      "Depository" means, with respect to the Securities of any Series issuable or
        issued in whole or in part in the form of one or more Global Securities, the person designated as Depository for such Series by the Company, which Depository shall be a clearing agency registered under the Exchange Act; and if at any time there is
        more than one such person, "Depository" as used with respect to the Securities of any Series shall mean the Depository with respect to the Securities of such Series.

       

      "Discount Security" means any Security that provides for an amount less than
        the stated principal amount thereof to be due and payable upon declaration of acceleration of the maturity thereof pursuant to Section 6.02.

       

      "Dollars" means the currency of The United States of America.

       

      "ECU" means the European Currency Unit as determined by the Commission of the
        European Union.

       

      "Exchange Act" means the Securities Exchange Act of 1934, as amended.

       

      "Foreign Currency" means any currency or currency unit issued by a government
        other than the government of The United States of America.

       

      

      
        
          2

          
            
 

        

      

      

      "Foreign Government Obligations" means with respect to Securities of any Series
        that are denominated in a Foreign Currency, (i) direct obligations of the government that issued or caused to be issued such currency for the payment of which obligations its full faith and credit is pledged or (ii) obligations of a person
        controlled or supervised by or acting as an agency or instrumentality of such government the timely payment of which is unconditionally guaranteed as a full faith and credit obligation by such government, which, in either case under clauses (i) or
        (ii), are not callable or redeemable at the option of the issuer thereof.

       

      "Global Security" or "Global
          Securities" means a Security or Securities, as the case may be, in the form established pursuant to Section 2.02 evidencing all or part of a Series of Securities, issued to the Depository for such Series or its nominee, and registered in
        the name of such Depository or nominee.

       

      "Holder" or "Securityholder"
        means a person in whose name a Security is registered.

       

      "Indenture" means this Indenture as amended and supplemented from time to time
        and shall include the form and terms of particular Series of Securities established as contemplated hereunder.

       

      "Interest," in respect of the Securities, unless the context otherwise
        requires, refers to interest payable on the Securities, including any additional interest that may become payable pursuant to Section 6.02(b).

       

      "Maturity," when used with respect to any Security or installment of principal
        thereof, means the date on which the principal of such Security or such installment of principal becomes due and payable as therein or herein provided, whether at the Stated Maturity or by declaration of acceleration, call for redemption, notice of
        option to elect repayment or otherwise.

       

      "Officer" means the Chairman of the Board, the President, any Vice-President,
        the Treasurer, the Secretary, any Assistant Treasurer or any Assistant Secretary of the Company.

       

      "Officers' Certificate" means a certificate signed by two Officers, one of whom
        must be the Company's principal executive officer, principal financial officer or principal accounting officer.

       

      "Opinion of Counsel" means a written opinion of legal counsel who is, and which
        opinion is, acceptable to the Trustee and its counsel.  Such legal counsel may be an employee of or counsel to the Company or the Trustee.

       

      "Person" means any individual, corporation, partnership, joint venture,
        association, limited liability company, joint-stock company, trust, unincorporated organization or government or any agency or political subdivision thereof.

       

      "Principal" or "principal"
        of a Security means the principal of the Security plus, when appropriate, the premium, if any, on, and any Additional Amounts in respect of, the Security.

       

      

      
        
          3

          
            
 

        

      

      

      "Responsible Officer" means any officer of the Trustee in its Corporate Trust
        Office and also means, any vice president, managing director, director, associate, assistant vice president, or any other officer of the Trustee customarily performing functions similar to those performed by any of the above designated officers and
        also, with respect to a particular corporate trust matter, any other officer to whom any corporate trust matter is referred because of his or her knowledge of and familiarity with a particular subject.

       

      "SEC" means the Securities and Exchange Commission.

       

      "Security" or "Securities"
        means the debentures, notes or other debt instruments of the Company of any Series authenticated and delivered under this Indenture.

       

      "Series" or "Series of
          Securities" means each series of debentures, notes or other debt instruments of the Company created pursuant to Sections 2.01 and 2.02 hereof.

       

      "Stated Maturity" when used with respect to any Security or any installment of
        principal thereof or interest thereon, means the date specified in such Security as the fixed date on which the principal of such Security or such installment of principal or interest is due and payable.

       

      "Subordinated Indebtedness" means any indebtedness which is expressly
        subordinated to the indebtedness evidenced by Securities.

       

      "Subsidiary" means, in respect of any Person, any corporation, association,
        partnership or other business entity of which more than 50% of the total voting power of shares of Capital Stock or other interests (including partnership interests) entitled (without regard to the occurrence of any contingency) to vote in the
        election of directors, managers, general partners or trustees thereof is at the time owned or controlled, directly or indirectly, by (i) such Person; (ii) such Person and one or more Subsidiaries of such Person; or (iii) one or more Subsidiaries of
        such Person.

       

      "TIA" means the Trust Indenture Act of 1939 (15 U.S. Code Sections
        77aaa-77bbbb) as in effect on the date of this Indenture; provided, however, that in the event the Trust Indenture Act of 1939 is amended after such date, "TIA" means, to the extent required by any such amendment, the Trust Indenture Act as so
        amended.

       

      "Trustee" means the person named as the "Trustee" in the first paragraph of
        this instrument until a successor Trustee shall have become such pursuant to the applicable provisions of this Indenture, and thereafter "Trustee" shall mean or include each person who is then a Trustee hereunder, and if at any time there is more
        than one such person, "Trustee" as used with respect to the Securities of any Series shall mean the Trustee with respect to Securities of that Series.

       

      "U.S. Government Obligations" means securities which are (i) direct obligations
        of The United States of America for the payment of which its full faith and credit is pledged or (ii) obligations of a person controlled or supervised by and acting as an agency or instrumentality of The United States of America the payment of
        which is unconditionally guaranteed as a full faith and credit obligation by The United States of America, and which in the case of (i) and (ii)

       

      

      
        
          4

          
            
 

        

      

      

      are not callable or redeemable at the option of the issuer thereof, and shall also include a depository receipt issued by a bank or
        trust company as custodian with respect to any such U.S. Government Obligation or a specific payment of interest on or principal of any such U.S. Government Obligation held by such custodian for the account of the holder of a depository receipt,
        provided that (except as required by law) such custodian is not authorized to make any deduction from the amount payable to the holder of such depository receipt from any amount received by the custodian in respect of the U.S. Government Obligation
        evidenced by such depository receipt.

       

      SECTION 1.02.  Other Definitions.

       

      
        
          	
                   

                  TERM

                	
                   

                  DEFINED IN SECTION

                
	
                  "Applicable Law"

                	
                  10.18

                
	
                  "Event of Default"

                	
                  6.01

                
	
                  "Instrument"

                	
                  6.01

                
	
                  "Journal"

                	
                  10.16

                
	
                  "Judgment Currency"

                	
                  10.17

                
	
                  "Legal Holiday"

                	
                  10.08

                
	
                  "mandatory sinking fund payment"

                	
                  11.01

                
	
                  "Market Exchange Rate"

                	
                  10.16

                
	
                  "New York Banking Day"

                	
                  10.17

                
	
                  "optional sinking fund payment"

                	
                  11.01

                
	
                  "Paying Agent"

                	
                  2.04

                
	
                  "Registrar"

                	
                  2.04

                
	
                  "Required Currency"

                	
                  10.17

                
	
                  "successor person"

                	
                  5.01

                
	
                  "Temporary Securities"

                	
                  2.11

                

        

         

      

      SECTION 1.03.  Incorporation by Reference of Trust Indenture Act.

       

      Whenever this Indenture refers to a provision of the TIA, the provision is incorporated by reference in and made a part of this
        Indenture.  This Indenture shall also include those provisions of the TIA required to be included herein by the provisions of the Trust Indenture Reform Act of 1990.  The following TIA terms used in this Indenture have the following meanings:

       

      "indenture securities" means the Securities.

       

      "indenture security holder" means a Securityholder.

       

      "indenture to be qualified" means this Indenture.

       

      "indenture trustee" or "institutional trustee" means the Trustee.

       

      "obligor" on the indenture securities means the Company and any successor
        obligor upon the Securities.

       

      

      
        
          5

          
            
 

        

      

      

      All other terms used in this Indenture that are defined by the TIA, defined by TIA reference to another statute or defined by SEC rule
        under the TIA and not otherwise defined herein are used herein as so defined.

       

      SECTION 1.04.  Rules of Construction.

       

      Unless the context otherwise requires:

       

      (a)           a term has the meaning assigned to it;

       

      (b)           an accounting term not otherwise defined has the meaning assigned to it in accordance with generally accepted accounting
        principles;

       

      (c)           references to "generally accepted accounting principles" shall mean generally accepted accounting principles in effect as
        of the time when and for the period as to which such accounting principles are to be applied;

       

      (d)           "or" is not exclusive;

       

      (e)           words in the singular include the plural, and in the plural include the singular;

       

      (f)           provisions apply to successive events and transactions;

       

      (g)           references to agreements and other instruments include subsequent amendments thereto;

       

      (h)           the term "merger" includes a statutory share exchange, and the term "merged" has a correlative meaning; and

       

      (i)           "herein," "hereof" and other words of similar import refer to this Indenture as a whole and not to any particular
        Article, Section or other subdivision.

       

      ARTICLE II

      

       

      THE SECURITIES

       

      SECTION 2.01.  Issuable in Series.

       

      The aggregate principal amount of Securities that may be authenticated and delivered under this Indenture is unlimited.  The Securities
        may be issued in one or more Series.  All Securities of a Series shall be identical except as may be set forth in a Board Resolution, a supplemental indenture or an Officers' Certificate detailing the adoption of the terms thereof pursuant to the
        authority granted under a Board Resolution.  In the case of Securities of a Series to be issued from time to time, the Board Resolution, Officers' Certificate or supplemental indenture may provide for the method by which specified terms (such as
        interest rate, maturity date, record date or date from which interest shall accrue) are to be determined.  Securities may

       

      

      
        
          6

          
            
 

        

      

      

      differ between Series in respect of any matters, provided that all Series of Securities shall be equally and ratably entitled to the
        benefits of the Indenture.

       

      SECTION 2.02.  Establishment of Terms of Series of Securities.

       

      At or prior to the issuance of any Securities within a Series, the following shall be established (as to the Series generally, in the
        case of Subsection (a), and either as to such Securities within the Series or as to the Series generally in the case of Subsections (b) through (t) by a Board Resolution, a supplemental indenture or an Officers' Certificate pursuant to authority
        granted under a Board Resolution:

       

      (a)           the title, designation, aggregate principal amount and authorized denominations of the Securities of the Series;

       

      (b)           the price or prices, (expressed as a percentage of the aggregate principal amount thereof) at which the Securities of the
        Series will be issued;

       

      (c)           the date or dates on which the principal of the Securities of the Series is payable;

       

      (d)           the rate or rates (which may be fixed or variable) per annum or, if applicable, the method used to determine such rate or
        rates (including, but not limited to, any commodity, commodity index, stock exchange index or financial index) at which the Securities of the Series shall bear interest, if any, the date or dates from which such interest, if any, shall commence and
        be payable and any regular record date for the interest payable on any interest payment date;

       

      (e)           any optional or mandatory sinking fund provisions or conversion or exchangeability provisions upon which Securities of
        the Series shall be redeemed, purchased, converted or exchanged;

       

      (f)           the date, if any, after which and the price or prices at which the Securities of the Series may be optionally redeemed or
        must be mandatorily redeemed and any other terms and provisions of optional or mandatory provisions;

       

      (g)           if other than denominations of $1,000 and any integral multiple thereof, the denominations in which the Securities of the
        Series shall be issuable;

       

      (h)           if other than the full principal amount, the portion of the principal amount of the Securities of the Series that shall
        be payable upon declaration of acceleration pursuant to Section 6.02 or provable in bankruptcy;

       

      (i)           any addition to or change in the Events of Default which applies to any Securities of the Series and any change in the
        right of the Trustee or the requisite Holders of such Securities to declare the principal amount thereof due and payable pursuant to Section 6.02;

       

      

      
        
          7

          
            
 

        

      

      

      (j)           the currency or currencies, including composite currencies, in which payments of principal of, premium or interest, if
        any, on the Securities of the Series will be payable, if other than the currency of the United States of America;

       

      (k)           if payments of principal of, premium or interest, if any, on the Securities of the Series will be payable, at the
        Company's election or at the election of any Holder, in a currency other than that in which the Securities of the Series are stated to be payable, the period or periods within which, and the terms and conditions upon which, the election may be
        made;

       

      (l)           if payments of interest, if any, on the Securities of the Series will be payable, at the Company's election or at the
        election of any Holder, in cash or additional securities, and the terms and conditions upon which the election may be made;

       

      (m)           if denominated in a currency or currencies other than the currency of the United States of America, the equivalent price
        of the Securities of the Series in the currency of the United States of America for purposes of determining the voting rights of Holders of the Securities of the Series;

       

      (n)           if the amount of payments of principal, premium or interest may be determined with reference to an index, formula or
        other method based on a coin or currency other than that in which the Securities of the Series are stated to be payable, the manner in which the amounts will be determined;

       

      (o)           any restrictive covenants or other material terms relating to the Securities of the Series;

       

      (p)           whether the Securities of the Series will be issued in the form of global securities or certificates in registered form;

       

      (q)           any terms with respect to subordination;

       

      (r)           any listing on any securities exchange or quotation system;

       

      (s)           additional provisions, if any, related to defeasance and discharge of the offered debt securities; and

       

      (t)           the applicability of any guarantees, which would be governed by New York law.

       

      All Securities of any one Series need not be issued at the same time and may be issued from time to time, consistent with the terms of
        this Indenture, if so provided by or pursuant to the Board Resolution, supplemental indenture or Officers' Certificate referred to above, and the authorized principal amount of any Series may not be increased to provide for issuance of additional
        Securities of such Series, unless otherwise provided in such Board Resolution, supplemental Indenture or Officers' Certificate.

       

      

      
        
          8

          
            
 

        

      

      

      SECTION 2.03.  Execution and Authentication.

       

      Two Officers shall sign the Securities for the Company by manual or facsimile signature.

       

      If an Officer whose signature is on a Security no longer holds that office at the time the Security is authenticated, the Security
        shall nevertheless be valid.

       

      A Security shall not be valid until authenticated by the manual signature of the Trustee or an authenticating agent.  The signature
        shall be conclusive evidence that the Security has been authenticated under this Indenture.

       

      The Trustee shall at any time, and from time to time, authenticate Securities for original issue in the principal amount provided in
        the Board Resolution, supplemental indenture hereto or Officers' Certificate, upon receipt by the Trustee of a Company Order.  Such Company Order may authorize authentication and delivery pursuant to oral or electronic instructions from the Company
        or its duly authorized agent or agents, which oral instructions shall be promptly confirmed in writing.  Each Security shall be dated the date of its authentication unless otherwise provided by a Board Resolution, a supplemental indenture hereto or
        an Officers' Certificate.

       

      The aggregate principal amount of Securities of any Series outstanding at any time may not exceed any limit upon the maximum principal
        amount for such Series set forth in the Board Resolution, supplemental indenture hereto or Officers' Certificate delivered pursuant to Section 2.02, except as provided in Section 2.08.

       

      Prior to the issuance of Securities of any Series, the Trustee shall have received and (subject to Section 7.02) shall be fully
        protected in relying on: (a) the Board Resolution, supplemental indenture hereto or Officers Certificate establishing the form of the Securities of that Series or of Securities within that Series and the terms of the Securities of that Series or of
        Securities within that Series, (b) an Officers' Certificate complying with Section 10.04, and (c) an Opinion of Counsel complying with Section 10.04.

       

      The Trustee shall have the right to decline to authenticate and deliver any Securities of such Series: (a) if the Trustee, being
        advised by counsel, determines that such action may not lawfully be taken; or (b) if a Responsible Officer of the Trustee in good faith shall determine that such action would expose the Trustee to personal liability to Holders of any then
        outstanding Series of Securities.

       

      The Trustee may appoint an authenticating agent acceptable to the Company to authenticate Securities.  An authenticating agent may
        authenticate Securities whenever the Trustee may do so.  Each reference in this Indenture to authentication by the Trustee includes authentication by such agent.  An authenticating agent has the same rights as an Agent to deal with the Company or
        an Affiliate.

       

      If any successor that has replaced the Company in accordance with Article 5 has executed an indenture supplemental hereto with the
        Trustee pursuant to Section 5.01, any of the Securities authenticated or delivered prior to such transaction may, from time to time, at the request of such successor, be exchanged for other Securities executed in the name of the such

       

      

      
        
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      successor with such changes in phraseology and form as may be appropriate, but otherwise identical to the Securities surrendered for
        such exchange and of like principal amount; and the Trustee, upon receipt of a Company Order of such successor, shall authenticate and deliver Securities as specified in such order for the purpose of such exchange.  If Securities shall at any time
        be authenticated and delivered in any new name of such successor pursuant to this provision of Section 2.03 in exchange or substitution for or upon registration of transfer of any Securities, such successor, at the option of the Holders but without
        expense to them, shall provide for the exchange of all Securities then outstanding for Securities authenticated and delivered in such new name.

       

      SECTION 2.04.  Registrar and Paying Agent.

       

      The Company shall maintain, with respect to each Series of Securities, at the place or places specified with respect to such Series
        pursuant to Section 2.02, an office or agency where Securities of such Series may be presented or surrendered for payment ("Paying Agent") and where Securities of such Series may be surrendered for registration of transfer or exchange
        ("Registrar").  The Registrar shall keep a register with respect to each Series of Securities and to their transfer and exchange.  The Company will give prompt written notice to the Trustee of the name and address, and any change in the name or
        address, of each Registrar and Paying Agent.  If at any time the Company shall fail to maintain any such required Registrar or Paying Agent or shall fail to furnish the Trustee with the name and address thereof, such presentations and surrenders
        may be made or served at the Corporate Trust Office of the Trustee, and the Company hereby appoints the Trustee as its agent to receive all such presentations and surrenders.

       

      The Company may also from time to time designate one or more co-registrars or additional paying agents and may from time to time
        rescind such designations; provided, however, that no such designation or rescission shall in any manner relieve the Company of its obligations to maintain a Registrar or Paying Agent in each place so specified pursuant to Section 2.02 for
        Securities of any Series for such purposes.  The Company will give prompt written notice to the Trustee of any such designation or rescission and of any change in the name or address of any such co-registrar or additional paying agent.  The term
        "Registrar" includes any co-registrar; and the term "Paying Agent" includes any additional paying agent.

       

      The Company hereby appoints [                  ] as the initial Registrar and Paying Agent for each Series unless another Registrar or
        Paying Agent as the case may be, is appointed prior to the time Securities of that Series are first issued.  Each Registrar and Paying Agent shall be entitled to all of the rights, protections, exculpations and indemnities afforded to the Trustee
        in connection with its roles as Registrar and Paying Agent.

       

      SECTION 2.05.  Paying Agent to Hold Money in Trust.

       

      The Company shall require each Paying Agent other than the Trustee to agree in writing that the Paying Agent will hold in trust, for
        the benefit of Securityholders of any Series of Securities, or the Trustee, all money held by the Paying Agent for the payment of principal of or interest on the Series of Securities, and will notify the Trustee of any default by the Company in
        making any such payment.  While any such default continues, the Trustee may require a Paying Agent to pay all money held by it to the Trustee.  The Company at any time may require

       

      

      
        
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      a Paying Agent to pay all money held by it to the Trustee.  Upon payment over to the Trustee, the Paying Agent (if other than the
        Company or a Subsidiary) shall have no further liability for the money.  If the Company or a Subsidiary acts as Paying Agent, it shall segregate and hold in a separate trust fund for the benefit of Securityholders of any Series of Securities all
        money held by it as Paying Agent.

       

      SECTION 2.06.  Securityholder Lists.

       

      The Trustee shall preserve in as current a form as is reasonably practicable the most recent list available to it of the names and
        addresses of Securityholders of each Series of Securities and shall otherwise comply with TIA Section 312(a).  If the Trustee is not the Registrar, the Company shall furnish to the Trustee at least [  ] days before each interest payment date and at
        such other times as the Trustee may request in writing a list, in such form and as of such date as the Trustee may reasonably require, of the names and addresses of Securityholders of each Series of Securities.

       

      SECTION 2.07.  Transfer and Exchange.

       

      Where Securities of a Series are presented to the Registrar or a co-registrar with a request to register a transfer or to exchange them
        for an equal principal amount of Securities of the same Series, the Registrar shall register the transfer or make the exchange if its requirements for such transactions are met.  To permit registrations of transfers and exchanges, the Trustee shall
        authenticate Securities at the Registrar's request.  Any exchange or transfer shall be without charge, except that the Company or the Registrar may require payment of a sum sufficient to cover any tax or other governmental charge required by law;
        provided that this sentence shall not apply to any exchange pursuant to Section 2.11, 2.08, 3.06 or 9.06.

       

      Neither the Company nor the Registrar shall be required (a) to issue, register the transfer of, or exchange Securities of any Series
        for the period beginning at the opening of business [  ] days immediately preceding the mailing of a notice of redemption of Securities of that Series selected for redemption and ending at the close of business on the day of such mailing, or (b) to
        register the transfer of or exchange Securities of any Series selected, called or being called for redemption as a whole or the portion being redeemed of any such Securities selected, called or being called for redemption in part.

       

      All Securities issued upon any transfer or exchange of Securities shall be valid obligations of the Company, evidencing the same debt
        and entitled to the same benefits under this Indenture, as the Securities surrendered upon such transfer or exchange.  Any Registrar appointed pursuant to Section 2.04 shall provide to the Trustee such information as the Trustee may reasonably
        require in connection with the delivery by such Registrar of Securities upon transfer or exchange of Securities.  Each Holder of a Security agrees to indemnify the Company and the Trustee against any liability that may result from the transfer,
        exchange or assignment of such Holder's Security in violation of any provision of this Indenture and/or applicable U.S. federal or state securities law.

      

      
        
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      SECTION 2.08.  Mutilated, Destroyed, Lost and Stolen Securities.

       

      If any mutilated Security is surrendered to the Registrar, the Company shall execute and the Trustee shall authenticate and deliver in
        exchange therefor a new Security of the same Series and of like tenor and principal amount and bearing a number not contemporaneously outstanding.

       

      If there shall be delivered to the Company and the Registrar (i) evidence to their satisfaction of the destruction, loss or theft of
        any Security and (ii) such security or indemnity as may be required by them to save each of them and any agent of either of them harmless, then, in the absence of notice to the Company or the Registrar that such Security has been acquired by a bona
        fide purchaser, the Company shall execute and upon its request the Trustee shall authenticate and make available for delivery, in lieu of any such destroyed, lost or stolen Security, a new Security of the same Series and of like tenor and principal
        amount and bearing a number not contemporaneously outstanding.

       

      In case any such mutilated, destroyed, lost or stolen Security has become or is about to become due and payable, the Company in its
        discretion may, instead of issuing a new Security, pay such Security.

       

      Upon the issuance of any new Security under this Section, the Company may require the payment of a sum sufficient to cover any tax or
        other governmental charge that may be imposed in relation thereto and any other expenses (including the fees and expenses of the Trustee) connected therewith.

       

      Every new Security of any series issued pursuant to this Section in lieu of any destroyed, lost or stolen Security shall constitute an
        original additional contractual obligation of the Company, whether or not the destroyed, lost or stolen Security shall be at any time enforceable by anyone, and shall be entitled to all the benefits of this Indenture equally and proportionately
        with any and all other Securities of that Series duly issued hereunder.

       

      The provisions of this Section are exclusive and shall preclude (to the extent lawful) all other rights and remedies with respect to
        the replacement or payment of mutilated, destroyed, lost or stolen Securities.

       

      SECTION 2.09.  Outstanding Securities.

       

      The Securities outstanding at any time are all the Securities authenticated by the Trustee except for those canceled by it, those
        delivered to it for cancellation, those reductions in the interest on a Global Security effected by the Trustee in accordance with the provisions hereof and those described in this Section as not outstanding.

       

      If a Security is replaced pursuant to Section 2.08, it ceases to be outstanding until the Trustee receives proof satisfactory to it
        that the replaced Security is held by a bona fide purchaser.

       

      If the Paying Agent (other than the Company, a Subsidiary or an Affiliate of any thereof) holds on the Maturity of Securities of a
        Series money sufficient to pay such Securities

       

      

      
        
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      payable on that date, then on and after that date such Securities of the Series cease to be outstanding and interest on them ceases to
        accrue.

       

      A Security does not cease to be outstanding because the Company or an Affiliate holds the Security.

       

      In determining whether the Holders of the requisite principal amount of outstanding Securities have given any request, demand,
        authorization, direction, notice, consent or waiver hereunder, the principal amount of a Discount Security that shall be deemed to be outstanding for such purposes shall be the amount of the principal thereof that would be due and payable as of the
        date of such determination upon a declaration of acceleration of the Maturity thereof pursuant to Section 6.02.

       

      SECTION 2.10.  Treasury Securities.

       

      In determining whether the Holders of the required principal amount of Securities of a Series have concurred in any request, demand,
        authorization, direction, notice, consent or waiver Securities of a Series owned by the Company or an Affiliate shall be disregarded, except that for the purposes of determining whether the Trustee shall be protected in relying on any such request,
        demand, authorization, direction, notice, consent or waiver only Securities of a Series that a Responsible Officer of the Trustee actually knows are so owned shall be so disregarded.

       

      SECTION 2.11.  Temporary Securities.

       

      Until definitive Securities are ready for delivery, the Company may prepare and the Trustee shall authenticate temporary securities
        upon a Company Order ("Temporary Securities").  Temporary Securities shall be substantially in the form of definitive Securities but may have variations that the Company considers appropriate for temporary Securities.  Without unreasonable delay,
        the Company shall prepare and the Trustee upon written request shall authenticate definitive Securities of the same Series and date of maturity in exchange for temporary Securities.  Until so exchanged, temporary securities shall have the same
        rights under this Indenture as the definitive Securities.

       

      SECTION 2.12.  Cancellation.

       

      The Company at any time may deliver Securities to the Trustee for cancellation.  The Registrar and the Paying Agent shall forward to
        the Trustee or its agent any Securities surrendered to them for transfer, exchange, payment or conversion.  The Trustee and no one else shall cancel, in accordance with its standard procedures, all Securities surrendered for transfer, exchange,
        payment, conversion or cancellation and shall deliver the cancelled Securities to the Company.  No Security shall be authenticated in exchange for any Security cancelled pursuant to this Section 2.12.

       

      The Company may, to the extent permitted by law, purchase Securities in the open market or by tender offer at any price or by private
        agreement.  Any Securities purchased or otherwise acquired by the Company or any of its Subsidiaries prior to the final maturity of such Securities may, to the extent permitted by law, be reissued or resold or may, at the option of the Company, be
        surrendered to the Trustee for cancellation.  Any Securities surrendered for

       

      

      
        
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      cancellation may not be reissued or resold and shall be promptly cancelled by the Trustee, and the Company may not hold or resell such
        Securities or issue any new Securities to replace any such Securities.

       

      SECTION 2.13.  Defaulted Interest.

       

      If the Company defaults in a payment of interest on a Series of Securities, it shall pay defaulted interest, plus, to the extent
        permitted by law, any interest payable on the defaulted interest at the Default Rate, to the persons who are Security holders of the Series on a subsequent special record date.  The Company shall fix the record date and payment date.  At least [  ]
        days before the record date, the Company shall mail to the Trustee and the Paying Agent and to each Securityholder of the Series a notice that states the record date, the payment date and the amount of interest to be paid.  The Company may pay
        defaulted interest in any other lawful manner.

       

      SECTION 2.14.  Global Securities.

       

      (a)           A Board Resolution, a supplemental indenture hereto or an Officers' Certificate shall establish whether the Securities of
        a Series shall be issued in whole or in part in the form of one or more Global Securities and the Depository for such Global Security or Securities.

       

      (b)            (i)           Notwithstanding any provisions to the contrary contained in Section 2.07 of the Indenture and in addition
        thereto, any Global Security shall be exchangeable pursuant to Section 2.07 of the Indenture for Securities registered in the names of Holders other than the Depository for such Security or its nominee only if (A) such Depository notifies the
        Company that it is unwilling or unable to continue as Depository for such Global Security or if at any time such Depository ceases to be a clearing agency registered under the Exchange Act, and, in either case, the Company fails to appoint a
        successor Depository within 90 days of such event, (B) the Company executes and delivers to the Trustee an Officers' Certificate to the effect that such Global Security shall be so exchangeable or (C) an Event of Default with respect to the
        Securities represented by such Global Security shall have happened and be continuing.

       

      (ii)           Except as provided in this Section 2.14(b), a Global Security may not be transferred except as a whole by the
        Depository with respect to such Global Security to a nominee of such Depository, by a nominee of such Depository to such Depository or another nominee of such Depository or by the Depository or any such nominee to a successor Depository or a
        nominee of such a successor Depository.

       

      (iii)           Securities issued in exchange for a Global Security or any portion thereof shall be issued in definitive, fully
        registered form, without interest coupons, shall have an aggregate principal amount equal to that of such Global Security or portion thereof to be so exchanged, shall be registered in such names and be in such authorized denominations as the
        Depository shall designate and shall bear the applicable legends provided for herein.  Any Global Security to be exchanged in whole shall be surrendered by the Depository to the Trustee, as Registrar.  With regard to any Global Security to be
        exchanged in part, either such Global Security shall be so surrendered for exchange or, if

       

      

      
        
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      the Registrar is acting as custodian for the Depository or its nominee with respect to such Global Security, the principal amount
        thereof shall be reduced by an amount equal to the portion thereof to be so exchanged, by means of an appropriate adjustment made on the records of the Trustee.  Upon any such surrender or adjustment, the Trustee shall authenticate and deliver the
        Security issuable on such exchange to or upon the order of the Depository or an authorized representative thereof.

       

      (iv)           The registered Holder may grant proxies and otherwise authorize any Person, including participants in the Depository
        and persons that may hold interests through participants in the Depository, to take any action which a Holder is entitled to take under this Indenture or the Securities.

       

      (v)           In the event of the occurrence of any of the events specified in 2.14(b)(i), the Company will promptly make available to
        the Trustee a reasonable supply of Certificated Securities in definitive, fully registered form, without interest coupons.  If (A) an event described in Section 2.14(b)(i)(A) or (B) occurs and definitive Certificated Securities are not issued
        promptly to all beneficial owners or (B) the Registrar receives from a beneficial owner instructions to obtain definitive Certificated Securities due to an event described in Section 2.14(b)(i)(C) and definitive Certificated Securities are not
        issued promptly to any such beneficial owner, the Company expressly acknowledges, with respect to the right of any Holder to pursue a remedy pursuant to Section 6.07 hereof, the right of any beneficial owner of Securities to pursue such remedy with
        respect to the portion of the Global Security that represents such beneficial owner's Securities as if such definitive certificated Securities had been issued.

       

      (vi)           Notwithstanding any provision to the contrary in this Indenture, so long as a Global Security remains outstanding and
        is held by or on behalf of the Depository, transfers of a Global Security, in whole or in part, or of any beneficial interest therein, shall only be made in accordance with Section 2.07, this Section 2.14(b) and the rules and procedures of the
        Depository for such Global Security to the extent applicable to such transaction and as in effect from time to time.

       

      (c)           Any Global Security issued hereunder shall bear a legend in substantially the following form:

       

      "This Security is a Global Security within the meaning of the Indenture hereinafter referred to and is registered in the name of the
        Depository or a nominee of the Depository.  This Security is exchangeable for Securities registered in the name of a person other than the Depository or its nominee only in the limited circumstances described in the Indenture, and may not be
        transferred except as a whole by the Depository to a nominee of the Depository, by a nominee of the Depository to the Depository or another nominee of the Depository or by the Depository or any such nominee to a successor Depository or a nominee of
        such a successor Depository."

       

      (d)           The Depository, as a Holder, may appoint agents and otherwise authorize participants to give or take any request, demand,
        authorization, direction, notice, consent, waiver or other action which a Holder is entitled to give or take under the Indenture.

       

      

      
        
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      (e)           Notwithstanding the other provisions of this Indenture, unless otherwise specified as contemplated by Section 2.02,
        payment of the principal of and interest, if any, on any Global Security shall be made to the Holder thereof at their registered office.

       

      (f)           At all times the Securities are held in book-entry form with a Depository, (i) the Trustee may deal with such Depository
        as the authorized representative of the Holders, (ii) the rights of the Holders shall be exercised only through the Depository and shall be limited to those established by law and agreement between the Holders and the Depository and/or direct
        participants of the Depository, (iii) the Depository will make book-entry transfers among the direct participants of the Depository and will receive and transmit distributions of principal and interest on the Securities to such direct participants;
        and (iv) the direct participants of the Depository shall have no rights under this Indenture, or any supplement hereto, under or with respect to any of the Securities held on their behalf by the Depository, and the Depository may be treated by the
        Trustee and its agents, employees, officers and directors as the absolute owner of the Securities for all purposes whatsoever.

       

      SECTION 2.15.  CUSIP Numbers.

       

      The Company in issuing the Securities may use "CUSIP", "CCN", "ISIN" or other identification numbers (if then generally in use), and,
        if so, the Trustee shall use "CUSIP", "CCN", "ISIN" or such other identification numbers in notices of redemption as a convenience to Holders; provided that any such notice may state that no representation is made as to the correctness of such
        numbers either as printed on the Securities or as contained in any notice of a redemption and that reliance may be placed only on the other elements of identification printed on the Securities, and any such redemption shall not be affected by any
        defect in or omission of such numbers.

       

      ARTICLE III

      

       

      REDEMPTION

       

      SECTION 3.01.  Notice to Trustee.

       

      The Company may, with respect to any series of Securities, reserve the right to redeem and pay the Series of Securities or may covenant
        to redeem and pay the Series of Securities or any part thereof prior to the Stated Maturity thereof at such time and on such terms as provided for in such Securities.  If a Series of Securities is redeemable and the Company wants or is obligated to
        redeem prior to the Stated Maturity thereof all or part of the Series of Securities pursuant to the terms of such Securities, it shall notify the Trustee and Registrar in writing of the redemption date and the principal amount of Series of
        Securities to be redeemed.  The Company shall give the notice at least [  ] days before the redemption date (or such shorter notice as may be acceptable to the Trustee and Registrar).

       

      SECTION 3.02.  Selection of Securities to be Redeemed.

       

      Unless otherwise indicated for a particular Series by a Board Resolution, a supplemental indenture or an Officers' Certificate, if less
        than all the Securities of a Series are to be redeemed, the Registrar shall select the Securities of the Series to be redeemed in accordance

       

      

      
        
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      with its customary procedures.  The Registrar shall make the selection from Securities of the Series outstanding not previously called
        for redemption.  The Registrar may select for redemption portions of the principal of Securities of the Series that have denominations larger than $1,000.  Securities of the Series and portions of them it selects shall be in amounts of $1,000 or
        whole multiples of $1,000 or, with respect to Securities of any Series issuable in other denominations pursuant to Section 2.02(g), the minimum principal denomination for each Series and integral multiples thereof.  Provisions of this Indenture
        that apply to Securities of a Series called for redemption also apply to portions of Securities of that Series called for redemption.

       

      SECTION 3.03.  Notice of Redemption.

       

      Unless otherwise indicated for a particular Series by Board Resolution, a supplemental indenture hereto or an Officers' Certificate, at
        least [  ] days but not more than [  ] days before a redemption date, the Company shall mail a notice of redemption by first-class mail to each Holder whose Securities are to be redeemed.

       

      The notice shall identify the Securities of the Series to be redeemed and shall state:

       

      (a)           the redemption date;

       

      (b)           the redemption price;

       

      (c)           the name and address of the Paying Agent;

       

      (d)           that Securities of the Series called for redemption must be surrendered to the Paying Agent to collect the redemption
        price;

       

      (e)           that interest on Securities of the Series called for redemption ceases to accrue on and after the redemption date; and

       

      (f)           any other information as may be required by the terms of the particular Series or the Securities of a Series being
        redeemed.

       

      At the Company's written request, the Trustee shall distribute the notice of redemption prepared by the Company in the Company's name
        and at its expense.

       

      SECTION 3.04.  Effect of Notice of Redemption.

       

      Once notice of redemption is mailed or published as provided in Section 3.03, Securities of a Series called for redemption become due
        and payable on the redemption date and at the redemption price.  A notice of redemption may not be conditional.  Upon surrender to the Paying Agent, such Securities shall be paid at the redemption price plus accrued interest to the redemption date.

       

      

      
        
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      SECTION 3.05.  Deposit of Redemption Price.

       

      On or before the redemption date, the Company shall deposit with the Paying Agent money sufficient to pay the redemption price of and
        accrued interest, if any, on all Securities to be redeemed on that date.

       

      SECTION 3.06.  Securities Redeemed in Part.

       

      Upon surrender of a Security that is redeemed in part, the Trustee shall authenticate for the Holder a new Security of the same Series
        and the same maturity equal in principal amount to the unredeemed portion of the Security surrendered.

       

      

      

      ARTICLE IV

      

       

      COVENANTS

       

      SECTION 4.01.  Payment of Principal and Interest.

       

      The Company covenants and agrees for the benefit of the Holders of each Series of Securities that it will duly and punctually pay the
        principal of and interest, if any, on the Securities of that Series in accordance with the terms of such Securities and this Indenture. 

      

      

      Unless otherwise provided under the terms of a particular Series of Securities:

      

      

      (a)           an installment of principal or interest shall be considered paid on the date it is due if the Paying Agent (other than
        the Company) holds by [] [a].m., New York City time, on that date money, deposited by the Company or an Affiliate thereof, sufficient to pay such installment.  The Company shall (in immediately available funds), to the fullest extent permitted by
        law, pay interest on overdue principal and overdue installments of interest at the rate borne by the Securities per annum; and

       

      (b)           payment of the principal of and interest on the Securities shall be made at the office or agency of the Company
        maintained for that purpose in [] (which shall initially be [], the Paying Agent) in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private debts; provided, however, that at the option of the Company payment of interest may be made by check mailed to the address of the Person entitled thereto as such address appears in the register; provided, further, that a Holder with an aggregate principal amount in excess of $[] will be paid by wire transfer in immediately available funds at the election of such Holder if such Holder has provided wire
        transfer instructions to the Company at least [  ] Business Days prior to the payment date.

       

      SECTION 4.02.  SEC Reports.

       

      So long as any Securities are outstanding, the Company shall (i) file with the SEC within the time periods prescribed by its rules and
        regulations and (ii) furnish to the Trustee and

       

      

      
        
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      the Holders of the Securities within [  ] days after the date on which the Company would be required to file the same with the SEC
        pursuant to its rules and regulations (giving effect to any grace period provided by Rule 12b-25 under the Exchange Act), all quarterly and annual financial information required to be furnished or filed with the SEC pursuant to Section 13 and
        Section 15(d) of the Exchange Act and, with respect to the annual consolidated financial statements only, a report thereon by the Company's independent auditors.  The Company also shall comply with the other provisions of TIA Section 314(a).

       

      Delivery of such reports, information and documents to the Trustee is for informational purposes only, and the Trustee's receipt of
        such shall not constitute constructive notice of any information contained therein or determinable from information contained therein, including the Company's compliance with any of its covenants hereunder (as to which the Trustee is entitled to
        rely exclusively on Officers' Certificates).  The Company shall not be required to file any report or other information with the SEC if the SEC does not permit such filing, although such reports shall be furnished to the Trustee.  Documents filed
        by the Company with the SEC via the SEC's EDGAR system (or any successor thereto) will be deemed furnished to the Trustee and the Holders of the Securities as of the time such documents are filed via EDGAR (or such successor).

       

      SECTION 4.03.  Compliance Certificate.

       

      The Company shall deliver to the Trustee, within [   ] days after the end of each fiscal year of the Company, an officers certificate
        signed by two of the Company's officers stating that a review of the activities of the Company and its Subsidiaries during the preceding fiscal year has been made under the supervision of the signing Officers with a view to determining whether the
        Company has kept, observed, performed and fulfilled its obligations under this Indenture, and further stating, as to each such Officer signing such certificate, that to the best of his knowledge the Company has kept, observed, performed and
        fulfilled each and every covenant contained in this Indenture and is not in default in the performance or observance of any of the terms, provisions and conditions hereof (or, if a Default or Event of Default shall have occurred, describing all
        such Defaults or Events of Default of which he may have knowledge in reasonable detail and the efforts to remedy the same).  For purposes of this Section 4.03, compliance shall be determined without regard to any grace period or requirement of
        notice provided pursuant to the terms of this Indenture.

       

      The Company shall deliver to the Trustee, within [  ] days after the occurrence thereof, written notice in the form of an Officers'
        Certificate of any Event of Default described in Section 6.01(e), (f), (g) or (h) and any event of which it becomes aware that with the giving of notice or the lapse of time would become such an Event of Default, its status and what action the
        Company is taking or proposes to take with respect thereto.  For the avoidance of doubt, a breach of a covenant under an Instrument that is not a payment default and that has not given rise to a right of acceleration under such Instrument shall not
        trigger the requirement to provide notice under this paragraph.

       

      

      
        
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      SECTION 4.04.  Stay, Extension and Usury Laws.

       

      The Company covenants (to the extent that it may lawfully do so) that it will not at any time insist upon, plead, or in any manner
        whatsoever claim or take the benefit or advantage of, any stay, extension or usury law wherever enacted, now or at any time hereafter in force, which may affect the covenants or the performance of this Indenture or the Securities; and the Company
        (to the extent it may lawfully do so) hereby expressly waives all benefit or advantage of any such law and covenants that it will not, by resort to any such law, hinder, delay or impede the execution of any power herein granted to the Trustee, but
        will suffer and permit the execution of every such power as though no such law has been enacted.

       

      SECTION 4.05.  Corporate Existence.

       

      Subject to Article V, the Company will do or cause to be done all things necessary to preserve and keep in full force and effect its
        corporate existence and the corporate, partnership or other existence of each Subsidiary in accordance with the respective organizational documents of each Subsidiary and the rights (charter and statutory), licenses and franchises of the Company
        and its Subsidiaries; provided, however, that the Company shall not be required to preserve any such right, license or franchise, or the corporate, partnership or other existence of any Subsidiary, if the Board of Directors shall determine that the
        preservation thereof is no longer desirable in the conduct of the business of the Company and its Subsidiaries taken as a whole and that the loss thereof is not adverse in any material respect to the Holders.

       

      SECTION 4.06.  Taxes.

       

      The Company shall, and shall cause each of its Subsidiaries to, pay prior to delinquency all taxes, assessments and governmental
        levies, except as contested in good faith and by appropriate proceedings.

       

      SECTION 4.07.  Additional Interest Notice.

       

      In the event that the Company is required to pay additional interest to Holders of Securities pursuant to Section 6.02(b) hereof, the
        Company shall provide a direction or order in the form of a written notice to the Trustee (and if the Trustee is not the Paying Agent, the Paying Agent) of the Company's obligation to pay such additional interest no later than [   ] Business Days
        prior to date on which any such additional interest is scheduled to be paid.  Such notice shall set forth the amount of additional interest to be paid by the Company on such payment date and direct the Trustee (or, if the Trustee is not the Paying
        Agent, the Paying Agent) to make payment to the extent it receives funds from the Company to do so.  The Trustee shall not at any time be under any duty or responsibility to any Holder to determine whether additional interest is payable, or with
        respect to the nature, extent, or calculation of the amount of additional interest owed, or with respect to the method employed in such calculation of additional interest.

       

      SECTION 4.08.  Further Instruments and Acts.

       

      The Company will execute and deliver such further instruments and do such further acts as may be reasonably necessary or proper to
        carry out more effectively the purposes of this Indenture.

       

      

      
        
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      ARTICLE V

       

      SUCCESSORS

       

      SECTION 5.01.  When Company May Merge, Etc.

       

      The Company shall not consolidate with, enter into a binding share exchange, or merge into any other Person in a transaction in which
        it is not the surviving entity, or sell, assign, convey, transfer or lease or otherwise dispose of all or substantially all of its properties and assets to any Person (a "successor person"), unless:

       

      (a)           the successor person (if any) is a corporation, partnership, trust or other entity organized and validly existing under
        the laws of Belgium, the United States, any state of the United States or the District of Columbia and expressly assumes by a supplemental indenture executed and delivered to the Trustee, in form satisfactory to the Trustee, the due and punctual
        payment of the principal of, and any interest on, all Securities and the performance or observance of every covenant of this Indenture on the part of the Company to be performed or observed;

       

      (b)           immediately after giving effect to the transaction, no Default or Event of Default, shall have occurred and be
        continuing; and

       

      (c)           the Company shall have delivered to the Trustee, prior to the consummation of the proposed transaction, an Officers'
        Certificate to the foregoing effect and an Opinion of Counsel stating that the proposed transaction and such supplemental indenture comply with this Indenture.

       

      SECTION 5.02.  Successor Corporation Substituted.

       

      Upon any consolidation or merger, or any sale, lease, conveyance or other disposition of all or substantially all of the assets of the
        Company in accordance with Section 5.01, the successor person formed by such consolidation or into or with which the Company is merged or to which such sale, lease, conveyance or other disposition is made shall succeed to, and be substituted for,
        and may exercise every right and power of, the Company under this Indenture with the same effect as if such successor person has been named as the Company herein; provided, however, that the predecessor company in the case of a sale, lease,
        conveyance or other disposition of all or substantially all of the assets of the Company shall not be released from the obligation to pay the principal of and interest, if any, on the Securities.

       

      ARTICLE VI

      

       

      DEFAULTS AND REMEDIES

       

      SECTION 6.01.  Events of Default.

       

      "Event of Default," wherever used herein with respect to securities of any Series, means any one of the following events, unless in the
        establishing Board Resolution,

       

      

      
        
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      supplemental indenture or Officers' Certificate, it is provided that such Series shall not have the benefit of said Event of Default:

       

      (a)           default in the payment of any interest on any Security of that Series when it becomes due and payable, and continuance of
        such default for a period of 30 days (unless the entire amount of such payment is deposited by the Company with the Trustee or with a Paying Agent prior to the expiration of such period of 30 days); or

       

      (b)           default in the payment of any principal of any Security of that Series at its Maturity; or

       

      (c)           default in the deposit of any sinking fund payment, when and as due in respect of any Security of that Series; or

       

      (d)           the Company fails to perform or comply with any of its other covenants or agreements contained in the Securities or in
        this Indenture (other than a covenant or agreement a default in whose performance or whose breach is specifically dealt with in clauses (a), (b) or (c) of this Section 6.01) and the default continues for 60 days after notice is given as specified
        below;

       

      (e)           any indebtedness under any bond, debenture, note or other evidence of indebtedness for money borrowed by the Company or
        any Subsidiary or under any mortgage, indenture or instrument under which there may be issued or by which there may be secured or evidenced any indebtedness for money borrowed by, or any other payment obligation of, the Company or any Subsidiary
        (an "Instrument") with a principal amount then, individually or in the aggregate, outstanding in excess of $[], whether such indebtedness now exists or shall hereafter be created, is not paid at Maturity or when otherwise due or is accelerated, and
        such indebtedness is not discharged, or such default in payment or acceleration is not cured or rescinded, within a period of 30 days after there shall have been given, by registered or certified mail, to the Company by the Trustee or to the
        Company and the Trustee by the Holders of at least [  ]% in aggregate principal amount of the outstanding Securities of that Series a written notice specifying such default and requiring the Company to cause such indebtedness to be discharged or
        cause such default to be cured or waived or such acceleration to be rescinded or annulled and stating that such notice is a "Notice of Default" hereunder.  A payment obligation (other than indebtedness under any bond, debenture, note or other
        evidence of indebtedness for money borrowed by the Company or any Subsidiary or under any mortgage, indenture or instrument under which there may be issued or by which there may be secured or evidenced any indebtedness for money borrowed by the
        Company or any Subsidiary) shall not be deemed to have matured, come due, or been accelerated to the extent that it is being disputed by the relevant obligor or obligors in good faith.  For the avoidance of doubt, the Maturity of an Instrument is
        the Maturity as set forth in that Instrument, as it may be amended from time to time in accordance with the terms of that Instrument;

       

      (f)           the Company or any Subsidiary fails to pay one or more final and non-appealable judgments entered by a court or courts of
        competent jurisdiction, the aggregate uninsured or unbonded portion of which is in excess of $[], if the judgments are not paid, discharged, waived or stayed within [  ] days;

       

      

      
        
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      (g)           the Company or any Subsidiary of the Company, pursuant to or within the meaning of any Bankruptcy Law:

       

      (i)           commences a voluntary case or proceeding;

       

      (ii)           consents to the entry of an order for relief against it in an involuntary case or proceeding;

       

      (iii)           consents to the appointment of a Custodian of it or for all or substantially all of its property; or

       

      (iv)           makes a general assignment for the benefit of its creditors; or

       

      (v)           or generally is unable to pay its debts as the same become due; or

       

      (h)           a court of competent jurisdiction enters an order or decree under any Bankruptcy Law that:

       

      (i)           is for relief against the Company or any of its Subsidiaries in an involuntary case or proceeding;

       

      (ii)           appoints a Custodian of the Company or any of its Subsidiaries for all or substantially all of the property of the
        Company or any such Subsidiary; or

       

      (iii)           orders the liquidation of the Company or any of its Subsidiaries;

       

      and the case of each of clause (i), (ii) and (iii), the order or decree remains unstayed and in effect for [  ] consecutive days; or

       

      (i)           any other Event of Default provided with respect to Securities of that Series, which is specified in a Board Resolution,
        a supplemental indenture hereto or an Officers' Certificate, in accordance with Section 2.02(i).

       

      A default under clause (d) above is not an Event of Default until the Trustee notifies the Company, or the Holders of at least [  ]% in
        aggregate principal amount of the Securities then outstanding notify the Company and the Trustee, in writing of the default, and the Company does not cure the default within 60 days after receipt of such notice.  The notice given pursuant to this
        Section 6.01 must specify the default, demand that it be remedied and state that the notice is a "Notice of Default."  When any default under this Section 6.01 is cured, it ceases.

       

      The Trustee shall not be charged with knowledge of any Event of Default unless written notice thereof shall have been given to a Trust
        Officer at the Corporate Trust Office of the Trustee by the Company, a Paying Agent, any Holder or any agent of any Holder. 

       

      SECTION 6.02.  Acceleration of Maturity; Rescission and Annulment.

       

      (a)           If an Event of Default (other than an Event of Default specified in clause (g) or (h) of Section 6.01) occurs and is
        continuing with respect to any Securities of any Series,

       

      

      
        
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      then in every such case, the Trustee may, by notice to the Company, or the Holders of at least 25% in aggregate principal amount of the
        Securities of that Series (or, if any Securities of that Series are Discount Securities, such portion of the principal amount as may be specified in the terms of such Securities) then outstanding may, by notice to the Company and the Trustee,
        declare all unpaid principal of, and accrued and unpaid interest on to the date of acceleration, the Securities of that Series then outstanding (if not then due and payable) to be due and payable upon any such declaration, and the same shall become
        and be immediately due and payable.  If an Event of Default specified in clause (g) or (h) of Section 6.01 occurs, all unpaid principal of the Securities then outstanding, and all accrued and unpaid interest thereon to the date of acceleration,
        shall ipso facto become and be immediately due and payable without any declaration or other act on the part of the Trustee or any Holder.  The Holders of a majority in aggregate principal amount of the Securities of that Series then outstanding by
        notice to the Trustee may rescind an acceleration of such Securities of that Series and its consequences if (a) all existing Events of Default, other than the nonpayment of the principal of the Securities which has become due solely by such
        declaration of acceleration, have been cured or waived; (b) to the extent the payment of such interest is lawful, interest (calculated at the Default Rate) on overdue installments of interest and overdue principal, which has become due otherwise
        than by such declaration of acceleration, has been paid; (c) the rescission would not conflict with any judgment or decree of a court of competent jurisdiction; and (d) all payments due to the Trustee and any predecessor Trustee under Section 7.07
        have been made.  No such rescission shall affect any subsequent default or impair any right consequent thereto.

       

      (b)           Notwithstanding any of provision of this Article 6, at the election of the Company in its sole discretion, the sole
        remedy under this Indenture for an Event of Default relating to the failure to comply with Section 4.02, and for any failure to comply with the requirements of Section 314(a)(1) of the TIA, will consist, for the 180 days after the occurrence of
        such an Event of Default, exclusively of the right to receive additional interest on the Securities at a rate equal to 0.50% per annum of the aggregate principal amount of the Securities then outstanding up to, but not including, the 181st day
        thereafter (or, if applicable, the earlier date on which the Event of Default relating to Section 4.02 is cured or waived).  Any such additional interest will be payable in the same manner and on the same dates as the stated interest payable on the
        Securities.  In no event shall additional interest accrue under the terms of this Indenture at a rate in excess of 0.50% per annum, in the aggregate, for any violation or default caused by the failure of the Company to be current in respect of its
        Exchange Act reporting obligations.  If the Event of Default is continuing on the 181st day after an Event of Default relating to a failure to comply with Section 4.02, the Securities will be subject to acceleration as provided in this
        Section 6.02.  The provisions of this Section 6.02(b) will not affect the rights of Holders in the event of the occurrence of any other Events of Default.

       

      In order to elect to pay additional interest as the sole remedy during the first 180 days after the occurrence of an Event of Default
        relating to the failure to comply with Section 4.02 in accordance with the immediately preceding paragraph, the Company shall notify all Holders and the Trustee and Paying Agent of such election on or before the close of business on the fifth
        Business Day after the date on which such Event of Default otherwise would occur.  Upon a failure by the Company to timely give such notice or pay additional interest, the Securities will be immediately subject to acceleration as otherwise provided
        in this Section 6.02.

       

      

      
        
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      SECTION 6.03.  Collection of Indebtedness and Suits for Enforcement by Trustee.

       

      If an Event of Default with respect to any Securities of any Series occurs and is continuing, the Trustee may in its discretion proceed
        to protect and enforce its rights and the rights of the Holders of Securities of such Series by such appropriate judicial proceedings as the Trustee shall deem most effectual to protect and enforce any such rights, whether for the specific
        enforcement of any covenant or agreement in this Indenture or in aid of the exercise of any power granted herein, or to enforce any other proper remedy.

       

      If an Event of Default in the payment of principal, interest, if any, specified in clause (a) or (b) of Section 6.01 occurs and is
        continuing, the Trustee may recover judgment in its own name and as trustee of an express trust against the Company or another obligor on the Securities for the whole amount of principal, and accrued interest remaining unpaid, if any, together
        with, to the extent that payment of such interest is lawful, interest on overdue principal, on overdue installments of interest, if any, in each case at the Default Rate, and such further amount as shall be sufficient to cover the costs and
        expenses of collection, including the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel.

       

      SECTION 6.04.  Trustee May File Proofs of Claim.

       

      In case of the pendency of any receivership, insolvency, liquidation, bankruptcy, reorganization, arrangement, adjustment, composition
        or other judicial proceeding relative to the Company or any other obligor upon the Securities or the property of the Company or of such other obligor or their creditors, the Trustee (irrespective of whether the principal of the Securities shall
        then be due and payable as therein expressed or by declaration or otherwise and irrespective of whether the Trustee shall have made any demand on the Company for the payment of overdue principal or interest) shall be entitled and empowered, by
        intervention in such proceeding or otherwise,

       

      (a)           to file and prove a claim for the whole amount of principal and interest owing and unpaid in respect of the Securities
        and to file such other papers or documents as may be necessary or advisable in order to have the claims of the Trustee (including any claim for the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and
        counsel) and of the Holders allowed in such judicial proceeding, and

       

      (b)           to collect and receive any moneys or other property payable or deliverable on any such claims and to distribute the same,
        and any custodian, receiver, assignee, trustee, liquidator, sequestrator or other similar official in any such judicial proceeding is hereby authorized by each Holder to make such payments to the Trustee and, in the event that the Trustee shall
        consent to the making of such payments directly to the Holders, to pay to the Trustee any amount due it for the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, and any other amounts due the
        Trustee under Section 7.07.

       

      

      
        
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      Nothing herein contained shall be deemed to authorize the Trustee to authorize or consent to or accept or adopt on behalf of any Holder
        any plan of reorganization, arrangement, adjustment or composition affecting the Securities or the rights of any Holder thereof or to authorize the Trustee to vote in respect of the claim of any Holder in any such proceeding.

       

      SECTION 6.05.  Trustee May Enforce Claims Without Possession of Securities.

       

      All rights of action and claims under this Indenture or the Securities may be prosecuted and enforced by the Trustee without the
        possession of any of the Securities or the production thereof in any proceeding relating thereto, and any such proceeding instituted by the Trustee shall be brought in its own name as trustee of an express trust, and any recovery of judgment shall,
        after provision for the payment of the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, be for the ratable benefit of the Holders of the Securities in respect of which such judgment has been
        recovered.

       

      SECTION 6.06.  Application of Money Collected.

       

      Any money collected by the Trustee pursuant to this Article shall be applied in the following order, at the date or dates fixed by the
        Trustee and, in case of the distribution of such money on account of principal or interest, upon presentation of the Securities and the notation thereon of the payment if only partially paid and upon surrender thereof if fully paid: and

       

      First: To the payment of all amounts due the Trustee under Section 7.07;

       

      Second: To the payment of the amounts then due and unpaid for principal of and
        interest on the Securities in respect of which or for the benefit of which such money has been collected, ratably, without preference or priority of any kind, according to the amounts due and payable on such Securities for principal and interest,
        respectively; and

       

      Third: To the Company.

       

      SECTION 6.07.  Limitation on Suits.

       

      No Holder of any Security of any Series shall have any right to institute any proceeding, judicial or otherwise, with respect to this
        Indenture, or for the appointment of a receiver or trustee, or for any other remedy hereunder (except actions for payment of overdue principal and interest), unless:

       

      (a)           such Holder has previously given written notice to the Trustee of a continuing Event of Default with respect to the
        Securities of that Series;

       

      (b)           the Holders of not less than [  ]% in principal amount of the outstanding Securities of that Series shall have made
        written request to the Trustee to institute proceedings in respect of such Event of Default in its own name as Trustee hereunder;

       

      (c)           such Holder or Holders have offered to the Trustee indemnity satisfactory to it against the costs, expenses and
        liabilities to be incurred in compliance with such request;

       

      

      
        
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      (d)           the Trustee for [  ] days after its receipt of such notice, request and offer of indemnity has failed to institute any
        such proceeding; and

       

      (e)           no direction inconsistent with such written request has been given to the Trustee during such [  ]-day period by the
        Holders of a majority in principal amount of the outstanding Securities of that Series; it being understood and intended that no one or more of such Holders shall have any right in any manner whatever by virtue of, or by availing of, any provision
        of this Indenture to affect, disturb or prejudice the rights of any other of such Holders, or to obtain or to seek to obtain priority or preference over any other of such Holders or to enforce any right under this Indenture, except in the manner
        herein provided and for the equal and ratable benefit of all such Holders.

       

      SECTION 6.08.  Unconditional Right of Holders to Receive Principal and
          Interest.

       

      Notwithstanding any other provision in this Indenture, the Holder of any Security shall have the right, which is absolute and
        unconditional, to receive payment of the principal of and interest, if any, on such Security on the Stated Maturity or Stated Maturities expressed in such Security (or, in the case of redemption, on the redemption date) and to institute suit for
        the enforcement of any such payment, and such rights shall not be impaired without the consent of such Holder.

       

      SECTION 6.09.  Restoration of Rights and Remedies.

       

      If the Trustee or any Holder has instituted any proceeding to enforce any right or remedy under this Indenture and such proceeding has
        been discontinued or abandoned for any reason, or has been determined adversely to the Trustee or to such Holder, then and in every such case, subject to any determination in such proceeding, the Company, the Trustee and the Holders shall be
        restored severally and respectively to their former positions hereunder and thereafter all rights and remedies of the Trustee and the Holders shall continue as though no such proceeding had been instituted.

       

      SECTION 6.10.  Rights and Remedies Cumulative.

       

      Except as otherwise provided with respect to the replacement or payment of mutilated, destroyed, lost or stolen Securities in Section
        2.08, no right or remedy herein conferred upon or reserved to the Trustee or to the Holders is intended to be exclusive of any other right or remedy, and every right and remedy shall, to the extent permitted by law, be cumulative and in addition to
        every other right and remedy given hereunder or now or hereafter existing at law or in equity or otherwise.  The assertion or employment of any right or remedy hereunder, or otherwise, shall not prevent the concurrent assertion or employment of any
        other appropriate right or remedy.

       

      SECTION 6.11.  Delay or Omission Not Waiver.

       

      No delay or omission of the Trustee or of any Holder of any Securities to exercise any right or remedy accruing upon any Event of
        Default shall impair any such right or remedy or constitute a waiver of any such Event of Default or an acquiescence therein.  Every right and

       

      

      
        
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      remedy given by this Article or by law to the Trustee or to the Holders may be exercised from time to time, and as often as may be
        deemed expedient, by the Trustee or by the Holders, as the case may be.

       

      SECTION 6.12.  Control by Holders.

       

      The Holders of a majority in principal amount of the outstanding Securities of any Series shall have the right to direct the time,
        method and place of conducting any proceeding for any remedy available to the Trustee, or exercising any trust or power conferred on the Trustee, with respect to the Securities of such Series, provided that

       

      (a)           such direction shall not be in conflict with any rule of law or with this Indenture,

       

      (b)           the Trustee may take any other action deemed proper by the Trustee which is not inconsistent with such direction; and

       

      (c)           subject to the provisions of Section 6.01, the Trustee shall have the right to decline to follow any such direction if
        the Trustee in good faith shall, by a Responsible Officer of the Trustee, determine that the proceeding so directed would involve the Trustee in personal liability or would be unduly prejudicial to the rights of another Holder or the Trustee.

       

      SECTION 6.13.  Waiver of Past Defaults.

       

      Subject to Section 9.02, the Holders of not less than a majority in principal amount of the outstanding Securities of any Series may on
        behalf of the Holders of all the Securities of such Series waive any past Default hereunder with respect to such Series and its consequences, except a Default in the payment of the principal of or interest on any Security of such Series (provided,
        however, that the Holders of a majority in principal amount of the outstanding Securities of any Series may rescind an acceleration and its consequences, including any related payment default that resulted from such acceleration).  Upon any such
        waiver, such Default shall cease to exist, and any Event of Default arising therefrom shall be deemed to have been cured, for every purpose of this Indenture; but no such waiver shall extend to any subsequent or other Default or impair any right
        consequent thereon.

       

      SECTION 6.14.  Undertaking for Costs.

       

      All parties to this Indenture agree, and each Holder of any Security by his acceptance thereof shall be deemed to have agreed, that any
        court may in its discretion require, in any suit for the enforcement of any right or remedy under this Indenture, or in any suit against the Trustee for any action taken, suffered or omitted by it as Trustee, the filing by any party litigant in
        such suit of an undertaking to pay the costs of such suit, and that such court may in its discretion assess reasonable costs, including reasonable attorneys' fees, against any party litigant in such suit, having due regard to the merits and good
        faith of the claims or defenses made by such party litigant; but the provisions of this Section shall not apply to any suit instituted by the Company, to any suit instituted by the Trustee, to any suit instituted by any Holder, or group of Holders,
        holding in the aggregate more than [  ]% in principal amount of the outstanding Securities of any Series, or to any suit instituted by any Holder for the enforcement of the

       

      

      
        
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      payment of the principal of or interest on any Security on or after the Stated Maturity or Stated Maturities expressed in such Security
        (or, in the case of redemption, on the redemption date).

       

      ARTICLE VII

      

       

      TRUSTEE

       

      SECTION 7.01.  Duties of Trustee.

       

      (a)           If an Event of Default has occurred and is continuing, the Trustee shall exercise the rights and powers vested in it by
        this Indenture and use the same degree of care and skill in their exercise as a prudent person would exercise or use under the circumstances in the conduct of his own affairs.

       

      (b)           Except during the continuance of an Event of Default:

       

      (i)           The Trustee  need perform only those duties that are specifically set forth in this Indenture and no implied duties,
        covenants or obligations shall be deemed to be imposed upon the Trustee.

       

      (ii)           in the absence of bad faith on its part, the Trustee may conclusively rely, as to the truth of the statements and the
        correctness of the opinions expressed therein, upon Officers' Certificates or Opinions of Counsel furnished to the Trustee and conforming to the requirements of this Indenture; however, in the case of any such Officers' Certificates or Opinions of
        Counsel which by any provisions hereof are specifically required to be furnished to the Trustee, the Trustee shall examine such Officers' Certificates and Opinions of Counsel to determine whether or not they conform on their face to the
        requirements of this Indenture.

       

      (c)           The Trustee may not be relieved from liability for its own its own negligent action, its own negligent failure to act or
        willful misconduct, except that:

       

      (i)           This paragraph does not limit the effect of paragraph (b) of Section 7.01 herein.

       

      (ii)           The Trustee shall not be liable for any error of judgment made in good faith by a Responsible Officer.

       

      (iii)           The Trustee shall not be liable with respect to any action taken, suffered or omitted to be taken by it with respect
        to Securities of any Series in good faith in accordance with the direction of the Holders of a majority in principal amount of the outstanding Securities of such Series relating to the time, method and place of conducting any proceeding for any
        remedy available to the Trustee, or exercising any trust or power conferred upon the Trustee, under this Indenture with respect to the Securities of such Series.

      

      (d)           Every provision of this Indenture that in any way relates to the Trustee is subject to paragraph (a), (b) and (c) of
        this Section.

       

       

      
        
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      (e)           The Trustee may refuse to perform any duty or exercise any right or power unless it receives an indemnity satisfactory to
        it against any loss, liability or expense.

       

      (f)           The Trustee shall not be liable for interest on any money received by it except as the Trustee may agree in writing with
        the Company.  Money held in trust by the Trustee need not be segregated from other funds except to the extent required by law.

       

      (g)           No provision of this Indenture shall require the Trustee to risk or expend its own funds or otherwise incur liability,
        financial or otherwise, in the performance of any of its duties, or in the exercise of any of its rights or powers, if it shall have reasonable grounds for believing that repayment of such funds or indemnity satisfactory to it against such risk is
        not reasonably assured to it.

       

      (h)           The Paying Agent, the Registrar and any authenticating agent shall be entitled to the same rights, indemnities,
        protections and immunities afforded to the Trustee.

       

      (i)           The Trustee shall have no duty to monitor the performance or compliance of the Company with its obligations hereunder or
        any under supplement hereto, nor shall it have any liability in connection with the malfeasance or nonfeasance by the Company.  The Trustee shall have no liability in connection with compliance by the Company with statutory or regulatory
        requirements related to this Indenture, any supplement or any Securities issued pursuant hereto or thereto.

       

      SECTION 7.02.  Rights of Trustee.

       

      (a)           The Trustee may conclusively rely on and shall be fully protected in acting or refraining from acting as a result of its
        reasonable belief that any resolution, certificate, statement, instrument, opinion, report, notice, request, consent, order, direction, approval or other paper or document was genuine and had been signed or presented by the proper person.  The
        Trustee need not investigate any fact or matter stated in the document, but the Trustee, in its discretion, may make such further inquiry or investigation into such facts or matters as it sees fit.

       

      (b)           Before the Trustee acts or refrains from acting, it may require an Officers' Certificate or an Opinion of Counsel or
        both.  The Trustee shall not be liable for any action it takes or omits to take in good faith in reliance on such Officers' Certificate or Opinion of Counsel.

       

      (c)           The Trustee may act through agents and shall not be responsible for the misconduct or negligence of, or for the
        supervision of, any agent appointed with due care.  No Depository shall be deemed an agent of the Trustee and the Trustee shall not be responsible for any act or omission by any Depository.

       

      (d)           The Trustee shall not be liable for any action it takes or omits to take in good faith which it believes to be authorized
        or within its rights or powers.

       

      (e)           The Trustee may consult with counsel of its selection and the advice of such counsel or any Opinion of Counsel shall be
        full and complete authorization and protection 

       

       

      
        
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      in respect of any action taken, suffered or omitted by it hereunder in good faith and in reliance thereon.

       

      (f)           The Trustee shall be under no obligation to exercise any of the rights or powers vested in it by or pursuant to this
        Indenture at the request, order or direction of any of the Holders of Securities, unless such Holders shall have offered to the Trustee reasonable security or indemnity satisfactory to it against the costs, expenses and liabilities which might be
        incurred by it in compliance with such request or direction.

       

      SECTION 7.03.  Individual Rights of Trustee.

       

      The Trustee, in its individual or any other capacity, may become the owner or pledgee of Securities and may otherwise deal with the
        Company or an Affiliate with the same rights it would have if it were not Trustee.  Any Agent may do the same with like rights.  The Trustee is also subject to Sections 7.10 and 7.11.

       

      SECTION 7.04.  Trustee's Disclaimer.

       

      The Trustee makes no representation as to the validity or adequacy of this Indenture or the Securities and the recitals contained
        herein and in the Securities shall be taken as statements of the Company and not of the Trustee, and the Trustee has no responsibility for such recitals. The Trustee shall not be accountable for the Company's use or application of the proceeds from
        the Securities or for monies paid over to the Company pursuant to this Indenture, and it shall not be responsible for any statement in the Securities other than its authentication.

       

      SECTION 7.05.  Notice of Defaults.

       

      If a Default or Event of Default occurs and is continuing with respect to the Securities of any Series and if a Responsible Officer of
        the Trustee has knowledge or receives written notice of such event, the Trustee shall mail to each Securityholder of the Securities of that Series, notice of a Default or Event of Default within [  ] days after it occurs or, if later, after a
        Responsible Officer of the Trustee has actual knowledge of such Default or Event of Default.  Except in the case of a Default or Event of Default in payment of principal of or interest on any Security of any Series, including any additional
        interest that may become payable pursuant to Section 6.02(b), the Trustee may withhold the notice so long as the Trustee in good faith determines that withholding the notice is in the interests of Securityholders of that Series.

       

      SECTION 7.06.  Reports by Trustee to Holders.

       

      Within [  ] days after [           ] in each year, the Trustee shall transmit by mail to all Securityholders, as their names and
        addresses appear on the register kept by the Registrar, a brief report dated as of such [], in accordance with, and to the extent required under, TIA Section 313.

       

      A copy of each report at the time of its mailing to Securityholders of any Series shall be filed with
          the SEC and each stock exchange on which the Securities of that Series are listed.  The Company shall promptly notify the Trustee when Securities of any Series are listed on any
          stock exchange.

       

       

      
        
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      SECTION 7.07.  Compensation and Indemnity.

       

      The Company shall pay to the Trustee from time to time such compensation for its services as shall be agreed upon in writing.  The
        Trustee's compensation shall not be limited by any law on compensation of a trustee of an express trust.  The Company shall reimburse the Trustee upon request for all reasonable out-of-pocket expenses, disbursements and advances incurred by
        it.  Such expenses shall include the reasonable compensation and expenses of the Trustee's agents, counsel and other persons not regularly in its employ.

       

      The Company shall indemnify, defend and hold harmless the Trustee and its officers, directors, employees, representatives and agents,
        from and against and reimburse the Trustee for any and all claims, expenses, obligations, liabilities, losses, damages, injuries (to person, property, or natural resources), penalties, stamp or other similar taxes, actions, suits, judgments,
        reasonable costs and expenses (including reasonable attorney's and agent's fees and expenses) of whatever kind or nature regardless of their merit, demanded, asserted or claimed against the Trustee directly or indirectly relating to, or arising
        from, claims against the Trustee by reason of its participation in the transactions contemplated hereby, including without limitation all reasonable costs required to be associated with claims for damages to persons or property, and reasonable
        attorneys' and consultants' fees and expenses and court costs except to the extent caused by the Trustee's negligence or willful misconduct.  The provisions of this Section 7.07 shall survive the termination of this Agreement or the earlier
        resignation or removal of the Trustee.  The Company shall defend any claim and the Trustee shall cooperate in the defense.  The Trustee may have separate counsel and the Company shall pay the reasonable fees and expenses of such counsel.  The
        Company need not pay for any settlement made without its consent, which consent shall not be unreasonably withheld or delayed.  This indemnification shall apply to officers, directors, employees, shareholders and agents of the Trustee.

       

      The Company need not reimburse any expense or indemnify against any loss liability incurred by the Trustee or by any officer, director,
        employee, shareholder or agent of the Trustee through negligence or bad faith.

       

      To secure the Company's payment obligations in this Section, the Trustee shall have a lien prior to the Securities of any Series on all
        money or property held or collected by the Trustee, except that held in trust to pay principal and interest on particular Securities of that Series.

       

      When the Trustee incurs expenses or renders services after an Event of Default specified in Section 6.01(f) or (g) occurs, the expenses
        and the compensation for the services are intended to constitute expenses of administration under any Bankruptcy Law.

       

      SECTION 7.08.  Replacement of Trustee.

       

      A resignation or removal of the Trustee and appointment of a successor Trustee shall become effective only upon the successor Trustee's
        acceptance of appointment as provided in this Section.

       

      The Trustee may resign with respect to the Securities of one or more Series by so notifying the Company.  The Holders of a majority in
        principal amount of the Securities of any 

       

      
        
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      Series may remove the Trustee with respect to that Series by so notifying the Trustee and the Company.  The Company may remove the
        Trustee with respect to Securities of one or more Series if:

       

      (a)           the Trustee fails to comply with Section 7.10;

       

      (b)           the Trustee is adjudged a bankrupt or an insolvent or an order for relief is entered with respect to the Trustee under
        any Bankruptcy Law;

       

      (c)           a Custodian or public officer takes charge of the Trustee or its property; or

       

      (d)           the Trustee becomes incapable of acting.

       

      If the Trustee resigns or is removed or if a vacancy exists in the office of Trustee for any reason, the Company shall promptly appoint
        a successor Trustee.  Within one year after the successor Trustee takes office, the Holders of a majority in principal amount of the then outstanding Securities may appoint a successor Trustee to replace the successor Trustee appointed by the
        Company.

       

      If a successor Trustee with respect to the Securities of any one or more Series does not take office within [  ] days after the
        retiring Trustee resigns or is removed, the retiring Trustee, the Company or the Holders of at least [  ]% in principal amount of the Securities of the applicable Series may petition any court of competent jurisdiction for the appointment of a
        successor Trustee.

       

      A successor Trustee shall deliver a written acceptance of its appointment to the retiring Trustee and to the Company.  Immediately
        after that, the retiring Trustee shall transfer all property held by it as Trustee to the successor Trustee subject to the lien provided for in Section 7.07, and subject to the payment of any and all amounts then due and owing to the retiring
        Trustee, the resignation or removal of the retiring Trustee shall become effective, and the successor Trustee shall have all the rights, powers and duties of the Trustee with respect to each Series of Securities for which it is acting as Trustee
        under this Indenture.  A successor Trustee shall mail a notice of its succession to each Securityholder of each such Series.  Notwithstanding replacement of the Trustee pursuant to this Section 7.08, the Company's obligations under Section 7.07
        hereof shall continue for the benefit of the retiring trustee with respect to expenses and liabilities incurred by it prior to such replacement.

       

      SECTION 7.09.  Successor Trustee by Merger, etc.

       

      If the Trustee consolidates with, merges or converts into, or transfers all or substantially all of its corporate trust business to,
        another corporation, the successor corporation without any further act shall be the successor Trustee with the same effect as if the successor Trustee had been named as the Trustee herein.

       

      SECTION 7.10.  Eligibility; Disqualification.

       

      This Indenture shall always have a Trustee who satisfies the requirements of TIA Section 310(a)(1), (2) and (5).  The Trustee shall
        always have a combined capital and surplus of 

       

      
        
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      at least $25,000,000 as set forth in its most recent published annual report of condition.  The Trustee shall comply with TIA Section
        310(b).

       

      SECTION 7.11.  Preferential Collection of Claims Against Company.

       

      The Trustee is subject to TIA Section 311(a), excluding any creditor relationship listed in TIA Section 311(b).  A Trustee who has
        resigned or been removed shall be subject to TTA Section 311(a) to the extent indicated.

       

      

      

      ARTICLE VIII

      

       

      SATISFACTION AND DISCHARGE; DEFEASANCE

       

      SECTION 8.01.  Satisfaction and Discharge of Indenture.

       

      This Indenture shall upon Company Order cease to be of further effect (except as hereinafter provided in this Section 8.01), and the
        Trustee, on the demand of and at the expense of the Company, shall execute proper instruments acknowledging satisfaction and discharge of this Indenture, when

       

      (a)           either

       

      (i)           all Securities theretofore authenticated and delivered (other than Securities that have been destroyed, lost or stolen
        and that have been replaced or paid) have been delivered to the Trustee for cancellation; or

       

      (ii)           all such Securities not theretofore delivered to the Trustee for cancellation have become due and payable, or

       

      (1)           have become due and payable, or

       

      (2)           will become due and payable at their Stated Maturity within [], or

       

      (3)           are to be called for redemption within [           ] under arrangements satisfactory to the Trustee for the giving of
        notice of redemption by the Trustee in the name, and at the expense, of the Company, or

       

      (4)           are deemed paid and discharged pursuant to section 8.03, as applicable; and the Company, in the case of (1), (2) or (3)
        above, has deposited or caused to be deposited with the Trustee as trust funds in trust an amount sufficient for the purpose of paying and discharging the entire indebtedness on such Securities not theretofore delivered to the Trustee for
        cancellation, for principal and interest to the date of such deposit (in the case of Securities which have become due and payable on or prior to the date of such deposit) or to the Stated Maturity or redemption date, as the case may be;

       

      

      
        
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      (b)           the Company has paid or caused to be paid all other sums payable hereunder by the Company; and

       

      (c)           the Company has delivered to the Trustee an Officers' Certificate and an Opinion of Counsel, each meeting the applicable
        requirements of Sections 10.04 and 10.05 and each stating that all conditions precedent herein relating to the satisfaction and discharge of this Indenture have been complied with and the Trustee receives written demand from the Company to
        discharge.

       

      Notwithstanding the satisfaction and discharge of this Indenture, the obligations of the Company to the Trustee under Section 7.07,
        and, if money shall have been deposited with the Trustee pursuant to clause (a) of this Section, the provisions of Sections 2.04, 2.07, 2.08, 8.01 8.02 and 8.05 shall survive.

       

      SECTION 8.02.  Application of Trust Funds; Indemnification.

       

      (a)           Subject to the provisions of Section 8.05, all money deposited with the Trustee pursuant to Section 8.01, all money and
        U.S. Government Obligations or Foreign Government Obligations deposited with the Trustee pursuant to Section 8.03 or 8.04 and all money received by the Trustee in respect of U.S. Government Obligations or Foreign Government Obligations deposited
        with the Trustee pursuant to Section 8.03 or 8.04, shall be held in trust and applied by it, in accordance with the provisions of the Securities and this Indenture, to the payment, either directly or through any Paying Agent (including the Company
        acting as its own Paying Agent) as the Trustee may determine, to the persons entitled thereto, of the principal and interest for whose payment such money has been deposited with or received by the Trustee or to make mandatory sinking fund payments
        or analogous payments as contemplated by Sections 8.03 or 8.04.

       

      (b)           The Company shall pay and shall indemnify the Trustee and the Agents against any tax, fee or other charge imposed on or
        assessed against U.S. Government Obligations or Foreign Government Obligations deposited pursuant to Sections 8.03 or 8.04 or the interest and principal received in respect of such obligations other than any payable by or on behalf of Holders.

       

      (c)           The Trustee shall, in accordance with the terms of this Indenture, deliver or pay to the Company from time to time, upon
        Company Request and at the expense of the Company any U.S. Government Obligations or Foreign Government Obligations or money held by it pursuant to this Indenture as provided in Sections 8.03 or 8.04 which, in the opinion of a nationally recognized
        firm of independent certified public accountants, expressed in a written certification thereof and delivered to the Trustee together with such Company Request, are then in excess of the amount thereof which then would have been required to be
        deposited for the purpose for which such U.S. Government Obligations or Foreign Government Obligations or money were deposited or received.  This provision shall not authorize the sale by the Trustee of any U.S. Government Obligations or Foreign
        Government Obligations held under this Indenture.

       

      

      
        
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      SECTION 8.03.  Legal Defeasance of Securities of any Series.

       

      Unless this Section 8.03 is otherwise specified, pursuant to Section 2.02(s), to be inapplicable to Securities of any Series, the
        Company shall be deemed to have paid and discharged the entire indebtedness on all the outstanding Securities of such Series on the [   ] day after the date of the deposit referred to in subparagraph (d) hereof, and the provisions of this
        Indenture, as it relates to such outstanding Securities of such Series, shall no longer be in effect (and the Trustee, at the expense of the company, shall, at Company Request, execute proper instruments acknowledging the same), except as to:

       

      (a)           the rights of Holders of Securities of such Series to receive, from the trust funds described in subparagraph (d) hereof,
        (i) payment of the principal of and each installment of principal of and interest on the outstanding Securities of such Series on the Stated Maturity of such principal or installment of principal or interest and (ii) the benefit of any mandatory
        sinking fund payments applicable to the Securities of such Series on the day on which such payments are due and payable in accordance with the terms of this Indenture and the Securities of such Series;

       

      (b)           the provisions of Sections 2.04, 2.07, 2.08, 2.14, 8.02, 8.03 and 8.05; and

       

      (c)           the rights, powers, trust and immunities of the Trustee hereunder; provided that, the following conditions shall have
        been satisfied:

       

      (d)           the Company shall have deposited or caused to be deposited irrevocably with the Paying Agent as trust funds in trust for
        the purpose of making the following payments, specifically pledged as security for and dedicated solely to the benefit of the Holders of such Securities in the case of Securities of such Series denominated in Dollars, cash in Dollars (or such other
        money or currencies as shall then be legal tender in the United States) and/or U.S. Government Obligations, or (ii) in the case of Securities of such Series denominated in a Foreign Currency (other than a composite currency), money and/or Foreign
        Government Obligations, which through the payment of interest and principal in respect thereof, in accordance with their terms, will provide (and without reinvestment and assuming no tax liability will be imposed on such Paying Agent), not later
        than [   ] day before the due date of any payment of money, an amount in cash, sufficient, in the opinion of a nationally recognized firm of independent public accountants expressed in a written certification thereof delivered to the Trustee and
        the Paying Agent, to pay and discharge each installment of principal (including mandatory sinking fund or analogous payments) of and interest, if any, on all the Securities of such Series on the dates such installments of interest or principal are
        due;

       

      (e)           such deposit will not result in a breach or violation of, or constitute a default under, this Indenture or any other
        agreement or instrument to which the Company is a party or by which it is bound;

       

      (f)           no Default or Event of Default with respect to the Securities of such Series shall have occurred and be continuing on the
        date of such deposit or during the period ending on the [    ] day after such date;

       

      (g)           the Company shall have delivered to the Trustee an Officers' Certificate and an Opinion of Counsel to the effect that (i)
        the Company has received from, or there has

       

      

      
        
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      been published by, the Internal Revenue Service a ruling, or (ii) since the date of execution of this Indenture, there has been a change
        in the applicable Federal income tax law, in either case to the effect that, and based thereon such Opinion of Counsel shall confirm that, the Holders of the Securities of such Series will not recognize income, gain or loss for Federal income tax
        purposes as a result of such deposit, defeasance and discharge and will be subject to Federal income tax on the same amount and in the same manner and at the same times as would have been the case if such deposit, defeasance and discharge had not
        occurred;

       

      (h)           the Company shall have delivered to the Trustee an Officers' Certificate stating that the deposit was not made by the
        Company with the intent of preferring the Holders of the Securities of such Series over any other creditors of the company or with the intent of defeating, hindering, delaying or defrauding any other creditors of the Company;

       

      (i)           such deposit shall not result in the trust arising from such deposit constituting an investment company (as defined in
        the Investment Company Act of 1940, as amended), or such trust shall be qualified under such Act or exempt from regulation thereunder; and

       

      (j)           the Company shall have delivered to the Trustee an Officers' Certificate and an Opinion of Counsel, each stating that all
        conditions precedent provided for relating to the defeasance contemplated by this Section have been complied with.

       

      SECTION 8.04.  Covenant Defeasance.

       

      Unless this Section 8.04 is otherwise specified pursuant to Section 2.02(s) to be inapplicable to Securities of any Series, on and
        after the [    ] day after the date of the deposit referred to in subparagraph (a) hereof, the Company may omit to comply with any term, provision or condition set forth under Sections 4.02, 4.03, 4.04, 4.05, 4.06, and 5.01 as well as any
        additional covenants contained in a supplemental indenture hereto for a particular Series of Securities or a Board Resolution or an Officers' Certificate delivered pursuant to Section 2.02(s) (and the failure to comply with any such covenants shall
        not constitute a Default or Event of Default under Section 6.01) and the occurrence of any event described in clause (e) of Section 6.01 shall not constitute a Default or Event of Default hereunder, with respect to the Securities of such Series,
        provided that the following conditions shall have been satisfied:

       

      (a)           With reference to this Section 8.04, the Company has deposited or caused to be irrevocably deposited (except as provided
        in Section 8.02(c)) with the Paying Agent as trust funds in trust, specifically pledged as security for, and dedicated solely to, the benefit of the Holders of such Securities (i) in the case of Securities of such Series denominated in Dollars,
        cash in Dollars (or such other money or currencies as shall then be legal tender in the United States) and/or U.S. Government Obligations, or (ii) in the case of Securities of such Series denominated in a Foreign Currency (other than a composite
        currency), money and/or Foreign Government Obligations, which through the payment of interest and principal in respect thereof, in accordance with their terms, will provide (and without reinvestment and assuming no tax liability will be imposed on
        such Paying Agent), not later than [   ] day before the due date of any payment of money, an amount in cash, sufficient, in the opinion of a nationally recognized firm of independent certified public accountants expressed in a written certification
        thereof delivered

       

      

      
        
          37

          
            
 

        

      

      

      to the Paying Agent, to pay principal and interest, if any, on and any mandatory sinking fund in respect of the Securities of such
        Series on the dates such installments of interest or principal are due;

       

      (b)           Such deposit will not result in a breach or violation of, or constitute a default under, this Indenture or any other
        agreement or instrument to which the Company is a party or by which it is bound;

       

      (c)           No Default or Event of Default with respect to the Securities of such Series shall have occurred and be continuing on the
        date of such deposit or during the period ending on the [    ] day after such date;

       

      (d)           the company shall have delivered to the Trustee an Opinion of Counsel confirming that Holders of the Securities of such
        Series will not recognize income, gain or loss for federal income tax purposes as a result of such deposit and defeasance and will be subject to federal income tax on the same amounts, in the same manner and at the same times as would have been the
        case if such deposit and defeasance had not occurred;

       

      (e)           the Company shall have delivered to the Trustee an Officers' Certificate stating the deposit was not made by the Company
        with the intent of preferring the Holders of the Securities of such Series over any other creditors of the Company or with the intent of defeating, hindering, delaying or defrauding any other creditors of the Company; and

       

      (f)           The Company shall have delivered to the Trustee an Officers' Certificate and an Opinion of Counsel, each stating that all
        conditions precedent herein provided for relating to the defeasance contemplated by this Section have been complied with.

       

      SECTION 8.05.  Repayment to Company.

       

      The Paying Agent shall pay to the Company upon request any money held by them for the payment of principal and interest that remains
        unclaimed for two years.  After that, Securityholders entitled to the money must look to the Company for payment as general creditors unless an applicable abandoned property law designates another person and all liability of the Paying Agent with
        respect to that money shall cease.

       

      

      

      ARTICLE IX

      

       

      AMENDMENTS AND WAIVERS

       

      SECTION 9.01.  Without Consent of Holders.

       

      The Company and the Trustee may amend or supplement this Indenture or the Securities of one or more Series without the consent of any
        Securityholder:

       

      (a)           to cure any ambiguity, defect or inconsistency;

       

      (b)           to comply with Article V;

       

      

      
        
          38

          
            
 

        

      

      

      (c)           to provide for uncertificated Securities in addition to or in place of certificated Securities;

       

      (d)           to make any change that does not adversely affect the rights of any Securityholder;

       

      (e)           to provide for the issuance of and establish the form and terms and conditions of Securities of any Series as permitted
        by this Indenture;

       

      (f)           to evidence and provide for the acceptance of appointment hereunder by a successor Trustee with respect to the Securities
        of one or more Series and to add to or change any of the provisions of this Indenture as shall be necessary to provide for or facilitate the administration of the trusts hereunder by more than one Trustee;

       

      (g)           to comply with requirements of the TIA and any rules promulgated under the TIA; and

       

      (h)           to add to the covenants of the Company for the equal and ratable benefit of the Holders or to surrender any right, power
        or option conferred upon the Company.

       

      Any amendment or supplement made solely to conform the provisions of this Indenture or the Securities of any Series to the description
        thereof contained in the final prospectus relating to such Series will be deemed not to adversely affect the rights of any Holder.

       

      SECTION 9.02.  With Consent of Holders.

       

      The Company and the Trustee may enter into a supplemental indenture with the written consent of the Holders of at least a majority in
        principal amount of the outstanding Securities of all Series affected by such supplemental indenture, taken together as one class (including consents obtained in connection with a tender offer or exchange offer for the Securities of such Series),
        for the purpose of adding any provisions to or changing in any manner or eliminating any of the provisions of this Indenture or of any supplemental indenture or of modifying in any manner the rights of the Securityholders of each such
        Series.  Except as provided in Section 6.13, the Holders of at least a majority in principal amount of the outstanding Securities of all Series affected by such waiver by notice to the Trustee, taken together as one class (including consents
        obtained in connection with a tender offer or exchange offer for the Securities of such Series) may waive compliance by the Company with any provision of this Indenture or the Securities with respect to such Series.

       

      It shall not be necessary for the consent of the Holders of Securities under this Section 9.02 to approve the particular form of any
        proposed supplemental indenture or waiver, but it shall be sufficient if such consent approves the substance thereof.  After a supplemental indenture or waiver under this section becomes effective, the Company shall mail to the Holders of
        Securities affected thereby a notice briefly describing the supplemental indenture or waiver.  Any failure by the Company to mail or publish such notice, or any defect therein, shall not, however, in any way impair or affect the validity of any
        such supplemental indenture or waiver.

       

      

      
        
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      SECTION 9.03.  Limitations.

       

      Without the consent of each Securityholder affected, an amendment or waiver may not:

       

      (a)           change the amount of Securities whose Holders must consent to an amendment, supplement or waiver, except to increase any
        such amount or to provide that certain provisions of this Indenture cannot be modified, amended or waived without the consent of the Holder of each outstanding Security affected thereby;

       

      (b)           reduce the amount of interest, or change the interest payment time, on any Security;

       

      (c)           waive a redemption payment or alter the redemption provisions (other than any alteration that would not materially
        adversely affect the legal rights of any Holder under this Indenture) or the price at which the Company is required to offer to purchase the Securities;

       

      (d)           reduce the principal or change the Stated Maturity of any Security or reduce the amount of, or postpone the date fixed
        for, the payment of any sinking fund or analogous obligation;

       

      (e)           reduce the principal amount payable of any Security upon Maturity;

       

      (f)           waive a Default or Event of Default in the payment of the principal of or interest, if any, on any Security (except a
        rescission of acceleration of the Securities of any Series by the Holders of at least a majority in principal amount of the outstanding Securities of such Series and a waiver of the payment default that resulted from such acceleration);

       

      (g)           change the place or currency of payment of principal of or interest, if any, on any Security other than that stated in
        the Security;

       

      (h)           impair the right of any Holder to receive payment of principal or, or interest on, the Securities of such Holder on or
        after the due dates therefor;

       

      (i)            impair the right to institute suit for the enforcement of any payment on, or with respect to, any Security;

       

      (j)            make any change in Sections 10.15 or 10.16;

       

      (k)           change the ranking of the Securities; or

       

      (l)           make any other change which is specified in a Board Resolution, a supplemental indenture hereto or an Officers'
        Certificate as a limitation under this Section.

       

      SECTION 9.04.  Compliance with Trust Indenture Act.

       

      Every amendment to this Indenture or the Securities of one or more Series shall be set forth in a supplemental indenture hereto that
        complies with the TIA as then in effect.

       

      

      
        
          40

          
            
 

        

      

      

      SECTION 9.05.  Revocation and Effect of Consents.

       

      Until an amendment or waiver becomes effective, a consent to it by a Holder of a Security is a continuing consent by the Holder and
        every subsequent Holder of a Security or portion of a Security that evidences the same debt as the consenting Holder's Security, even if notation of the consent is not made on any Security.  However, any such Holder or subsequent Holder may revoke
        the consent as to his Security or portion of a Security if the Trustee receives the notice of revocation before the date the amendment or waiver becomes effective.

       

      Any amendment or waiver once effective shall bind every Securityholder of each Series affected by such amendment or waiver unless it is
        of the type described in any of clauses (a) through (g) of Section 9.03 in that case, the amendment or waiver shall bind each Holder of a Security who has consented to it and every subsequent Holder of a Security or portion of a Security that
        evidences the same debt as the consenting Holder's Security.

       

      SECTION 9.06.  Notation on or Exchange of Securities.

       

      If an amendment, supplement or waiver changes the terms of a Security, the Trustee may require the Holder of the Security to deliver it
        to the Trustee and the Trustee may place an appropriate notation on the Security about the changed terms and return it to the Holder.  Alternatively, if the Company or the Trustee so determines, the Company shall issue and the Trustee shall
        authenticate upon request new Securities of that Series that reflect the changed terms.

       

      SECTION 9.07.  Trustee Protected.

       

      In executing, or accepting the additional trusts created by, any supplemental indenture permitted by this Article or the modifications
        thereby of the trusts created by this Indenture, the Trustee shall be entitled to receive, and (subject to Section 7.01) shall be fully protected in relying upon, an Opinion of Counsel or an Officer's Certificate, or both stating that the execution
        of such supplemental indenture is authorized or permitted by this Indenture.  The Trustee shall sign all supplemental indentures, except that the Trustee need not sign any supplemental indenture that adversely affects its rights, duties or
        indemnities.

       

      SECTION 9.08.  Effect of Supplemental Indenture.

       

      Upon the execution of any supplemental indenture under this Article, this Indenture shall be modified in accordance therewith, and each
        such supplemental indenture shall form part of this Indenture for all purposes with respect to the relevant Series; and every Holder of Securities of the relevant Series theretofore or thereafter authenticated and delivered hereunder shall be bound
        thereby.

       

      

      
        
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      ARTICLE X

      

      

      MISCELLANEOUS

       

       

      SECTION 10.01.  Trust Indenture Act Controls.

       

      If any provision of this Indenture limits, qualifies, or conflicts with another provision which is required or deemed to be included in
        this Indenture by the TIA, such required or deemed provision shall control.

       

      SECTION 10.02.  Notices.

       

      Any notice or communication by the Company, the Trustee, the Paying Agent or the Registrar to another is duly given if in writing and
        delivered in person or mailed by first-class mail:

       

      if to the Company:

       

      EURONAV NV

      

      De Gerlachekaai 20

      

      2000 Antwerpen, Belgium

      

      

      

      if to the Trustee:

       

      [                                ]

      Attn: [                      ]

      Fax:   [                      ]

       

      if to the Registrar or Paying Agent:

       

      [                                ]

      Attn: [                      ]

      Fax:   [                      ]

      

      

      with copy to:

      

      

      [                                ]

      Attn: [                      ]

      Fax: [                        ]

      

      

      The Company, the Trustee and each Agent by notice to each other may designate additional or different addresses for subsequent notices
        or communications.

       

      Any notice or communication to a Securityholder shall be mailed by first-class mail to his address shown on the register kept by the
        Registrar.  Failure to mail a notice or

       

       

      
        
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       communication to a Securityholder of any Series or any defect in it shall not affect its sufficiency with respect to other
        Securityholders of that or any other Series.

       

      If a notice or communication is mailed or published in the manner provided above, within the time prescribed, it is duly given, whether
        or not the Securityholder receives it.

       

      If the company mails a notice or communication to Securityholders, it will mail a copy to the Trustee and each Agent at the same time.

       

      Whenever a notice is required to be given by the Company, such notice may be given by the Trustee or Registrar on the Company's behalf
        (and the Company will make any notice it is required to give to Holders available on its website).

       

      SECTION 10.03.  Communication by Holders with Other Holders.

       

      Securityholders of any Series may communicate pursuant to TIA Section 312(b) with other Securityholders of that Series or any other
        Series with respect to their rights under this Indenture or the Securities of that Series or all Series.  The Company, the Trustee, the Registrar and anyone else shall have the protection of TIA Section 312(c).

       

      SECTION 10.04.  Certificate and Opinion as to Conditions Precedent.

       

      Upon any request or application by the Company to the Trustee to take any action under this Indenture, the Company shall furnish to the
        Trustee:

       

      (a)           an Officers' Certificate stating that, in the opinion of the signers, all conditions precedent, if any, provided for in
        this Indenture relating to the proposed action have been complied with; and

       

      (b)           an Opinion of Counsel stating that, in the opinion of counsel, all such conditions precedent (including any covenants,
        compliance with which constitutes a condition precedent) have been complied with.

       

      SECTION 10.05.  Statements Required in Certificate or Opinion.

       

      Each certificate or opinion with respect to compliance with a condition or covenant provided for in this Indenture (other than a
        certificate provided pursuant to TIA Section 314(a)(4)) shall comply with the provisions of TIA Section 314(e) and shall include:

       

      (a)           a statement that the person making such certificate or opinion has read such covenant or condition;

       

      (b)           a brief statement as to the nature and scope of the examination or investigation  upon which the statements or
        opinions  contained in such certificate or opinion are based;

       

       

      
        
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      (c)           a statement that, in the opinion of such person, he has made such examination or investigation as is necessary to enable
        him to express an informed opinion as to whether or not such covenant or condition has been complied with; and

       

      (d)           a statement as to whether or not, in the opinion of such person, such condition or covenant has been complied with. 

       

      provided, however, that with respect to matters of fact an Opinion of Counsel
        may rely on an Officers' Certificate or certificates of public officials.

       

      SECTION 10.06.  Record Date for Vote or Consent of Holders.

       

      The Company (or, in the event deposits have been made pursuant to Section 11.02, the Trustee) may set a record date for purposes of
        determining the identity of Holders entitled to vote or consent to any action by vote or consent authorized or permitted under this Indenture, which record date shall not be more than [  ] days prior to the date of the commencement of solicitation
        of such action.  Notwithstanding the provisions of Section 9.05, if a record date is fixed, those persons who were Holders of Securities at the close of business on such record date (or their duly designated proxies), and only those persons, shall
        be entitled to take such action by vote or consent or to revoke any vote or consent previously given, whether or not such persons continue to be Holders after such record date.

       

      SECTION 10.07.  Rules by Trustee and Agents.

       

      The Trustee may make reasonable rules for action by or a meeting of Securityholders of one or more Series.  Any Agent may make
        reasonable rules and set reasonable requirements for its functions.

       

      SECTION 10.08.  Legal Holidays.

       

      Unless otherwise provided by Board Resolution, Officers' Certificate or supplemental indenture for a particular Series, a "Legal
        Holiday" is any day that is not a Business Day.  If a payment date is a Legal Holiday at a place of payment, payment may be made at that place on the next succeeding day that is not a Legal Holiday, and no interest shall accrue for the intervening
        period.

       

      SECTION 10.09.  No Recourse Against Others.

       

      A director, officer, employee or stockholder, as such, of the Company shall not have any liability for any obligations of the Company
        under the Securities or the Indenture or for any claim based on, in respect of or by reason of such obligations or their creation.  Each Securityholder by accepting a Security waives and releases all such liability.  The waiver and release are part
        of the consideration for the issue of the Securities.

       

      SECTION 10.10.  Counterparts.

       

       

      
        
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      This Indenture may be executed in any number of counterparts and by the parties hereto in separate counterparts, each of which when so
        executed shall be deemed to be an original and all of which taken together shall constitute one and the same agreement.

      

      SECTION 10.11.  Governing Laws and Submission to Jurisdiction.

       

      THIS INDENTURE AND THE SECURITIES SHALL BE GOVERNED BY THE LAWS OF THE STATE OF NEW YORK EXCLUDING ANY RULE OF LAW THAT WOULD CAUSE THE
        APPLICATION OF THE LAWS OF ANY JURISDICTION OTHER THAN THE STATE OF NEW YORK.

       

      The Company agrees that any legal suit, action or proceeding arising out of or based upon this Indenture may be instituted in any
        federal or state court sitting in New York City, and, to the fullest extent permitted by law, waives any objection which it may now or hereafter have to the laying of venue of any such proceeding, and irrevocably submits to the non-exclusive
        jurisdiction of such court in any suit, action or proceeding.  The Company, as long as any Securities remain outstanding or the parties hereto have any obligation under this Indenture, shall have an authorized agent in the United States upon whom
        process may be served in any such legal action or proceeding. Service of process upon such agent and written notice of such service mailed or delivered to it shall to the extent permitted by law be deemed in every respect effective service of
        process upon it in any such legal action or proceeding and, if it fails to maintain such agent, any such process or summons may be served by mailing a copy thereof by registered mail, or a form of mail substantially equivalent thereto, addressed to
        it at its address as provided for notices hereunder. The Company hereby appoints Seward & Kissel LLP, One Battery Park Plaza, New York, NY,  10004, as its agent for such purposes, and covenants and agrees that service of process in any legal
        action or proceeding may be made upon it at such office of such agent.

      

      

      SECTION 10.12.  No Adverse Interpretation of Other Agreements.

       

      This Indenture may not be used to interpret another indenture, loan or debt agreement of the Company or a Subsidiary.  Any such
        indenture, loan or debt agreement may not be used to interpret this Indenture.

       

      SECTION 10.13.  Successors.

       

      All agreements of the Company in this Indenture and the Securities shall bind its successor.  All agreements of the Trustee in this
        Indenture shall bind its successor.

       

      SECTION 10.14.  Severability.

       

      In case any provision in this Indenture or in the Securities shall be invalid, illegal or unenforceable, the validity, legality and
        enforceability of the remaining provisions shall not in any way be affected or impaired thereby.

       

      SECTION 10.15.  Table of Contents, Headings, Etc.

       

       

      
        
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      The Table of Contents, Cross Reference Table, and headings of the Articles and Sections of this
          Indenture have been inserted for convenience of reference only, are not to be considered a part hereof, and shall in no way modify or restrict any of the terms or provisions hereof.

      

      SECTION 10.16.  Securities in a Foreign Currency or in ECU.

       

      Unless otherwise specified in a Board Resolution, a supplemental indenture hereto or an Officers' Certificate delivered pursuant to
        Section 2.02 of this Indenture with respect to a particular Series of Securities, whenever for purposes of this Indenture any action may be taken by the Holders of a specified percentage in aggregate principal amount of Securities of all Series or
        all Series affected by a particular action at the time outstanding and, at such time, there are outstanding Securities of any Series which are denominated in a coin or currency other than Dollars (including ECUs), then the principal amount of
        Securities of such Series which shall be deemed to be outstanding for the purpose of taking such action shall be that amount of Dollars that could be obtained for such amount at the Market Exchange Rate at such time.  For purposes of this Section
        10.16, "Market Exchange Rate" shall mean the noon Dollar buying rate in New York City for cable transfers of that currency as published by the Federal Reserve Bank of New York; provided, however, in the case of ECUs, Market Exchange Rate shall mean
        the rate of exchange determined by the Commission of the European Union (or any successor thereto) as published in the Official Journal of the European Union (such publication or any successor publication, the "Journal").  If such Market Exchange
        Rate is not available for any reason with respect to such currency, the Trustee shall use, without liability on its part, such quotation of the Federal Reserve Bank of New York or, in the case of ECUs, the rate of exchange as published in the
        Journal, as of the most recent available date, or quotations or, in the case of ECUs, rates of exchange from one or more major banks in The City of New York or in the country of issue of the currency in question or, in the case of ECUs, in
        Luxembourg or such other quotations or, in the case of ECUs, rates of exchange as the Trustee, upon consultation with the Company, shall deem appropriate.  The provisions of this paragraph shall apply in determining the equivalent principal amount
        in respect of Securities of a Series denominated in currency other than Dollars in connection with any action taken by Holders of Securities pursuant to the terms of this Indenture.

       

      All decisions and determinations of the Trustee regarding the Market Exchange Rate or any alternative determination provided for in the
        preceding paragraph shall be in its sole discretion and shall, in the absence of manifest error, be conclusive to the extent permitted by law for all purposes and irrevocably binding upon the Company and all Holders.

       

      SECTION 10.17.  Judgment Currency.

       

      The Company agrees, to the fullest extent that it may effectively do so under applicable law, that (a) if for the purpose of obtaining
        judgment in any court it is necessary to convert the sum due in respect of the principal of or interest or other amount on the Securities of any Series (the "Required Currency") into a currency in which a judgment will be rendered (the "Judgment
        Currency"), the rate of exchange used shall be the rate at which in accordance with normal banking procedures the Trustee could purchase in The City of New York the Required Currency with the Judgment Currency on the day on which final unappealable
        judgment is 

       

       

      
        
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      entered, unless such day is not a New York Banking Day, then, the rate of exchange used shall be the rate
          at which in accordance with normal banking procedures the Trustee could purchase in The City of New York the Required Currency with the Judgment Currency on the New York Banking Day preceding the day on which final unappealable judgment is
          entered and (b) its obligations under this Indenture to make payments in the Required Currency (i) shall not be discharged or satisfied by any tender, any recovery pursuant to
          any judgment (whether or not entered in accordance with subsection (a)), in any currency other than the Required Currency, except to the extent that such tender or recovery shall result in the actual receipt, by the payee, of the full amount of
          the Required Currency expressed to be payable in respect of such payments, (ii) shall be enforceable as an alternative or additional cause of action for the purpose of recovering in the Required Currency the amount, if any, by which such actual
          receipt shall fall short of the full amount of the Required Currency so expressed to be payable, and (iii) shall not be affected by judgment being obtained for any other sum due under this Indenture.  For purposes of the foregoing, "New York
          Banking Day" means any day except a Saturday, Sunday or a legal holiday in The City of New York on which banking institutions are authorized or required by law, regulation or executive order to close.

       

      SECTION 10.18.  Compliance with Applicable Anti-Terrorism and Money Laundering Regulations.

       

      In order to comply with the laws, rules, regulations and executive orders in effect from time to time applicable to banking
        institutions, including those relating to the funding of terrorist activities and money laundering ("Applicable Law"), the Trustee is required to obtain, verify and record certain information relating to individuals and entities which maintain a
        business relationship with the Trustee.  Accordingly, each of the parties agree to provide to the Trustee, upon its request from time to time such identifying information and documentation as may be available for such party in order to enable the
        Trustee to comply with the Applicable Law.

       

      ARTICLE XI

      

       

      SINKING FUNDS

       

      SECTION 11.01.  Applicability of Article.

       

      The provisions of this Article shall be applicable to any sinking fund for the retirement of the Securities of a Series, except as
        otherwise permitted or required by any form of Security of such Series issued pursuant to this Indenture.

       

      The minimum amount of any sinking fund payment provided for by the terms of the Securities of any Series is herein referred to as a
        "mandatory sinking fund payment" and any other amount provided for by the terms of Securities of such Series is herein referred to as an "optional sinking fund payment." If provided for by the terms of Securities of any Series, the cash amount of
        any sinking fund payment may be subject to reduction as provided in Section 11.02.  Each sinking fund payment shall be applied to the redemption of Securities of any Series as provided for by the terms of the securities of such Series.

       

       

      
        
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      SECTION 11.02.  Satisfaction of Sinking Fund Payments with Securities.

       

      The Company may, in satisfaction of all or any part of any sinking fund payment with respect to the
          Securities of any Series to be made pursuant to the terms of such Securities (1) deliver outstanding Securities of such Series to which such sinking fund payment is applicable (other than any of such Securities previously called for mandatory
          sinking fund redemption) and (2) apply as credit Securities of such Series to which such sinking fund payment is applicable and which have been redeemed either at the election
          of the Company pursuant to the terms of such Series of Securities (except pursuant to any mandatory sinking fund) or through the application of permitted optional sinking fund payments or other optional redemptions pursuant to the terms of such
          Securities, provided that such Securities have not been previously so credited.  Such Securities shall be received by the Registrar, together with an Officers' Certificate with respect thereto, not later than [  ] days prior to the date on which
          the Registrar begins the process of selecting Securities for redemption, and shall be credited for such purpose by the Registrar at the price specified in such Securities for redemption through operation of the sinking fund and the amount of such
          sinking fund payment shall be reduced accordingly.  If as a result of the delivery or credit of Securities in lieu of cash payments pursuant to this Section 11.02, the principal amount of Securities of such Series to be redeemed in order to
          exhaust the aforesaid cash payment shall be less than $[              ], the Registrar need not call Securities of such Series for redemption, except upon receipt of a Company Order that such action be taken, and such cash payment shall be held
          by the Paying Agent and applied to the next succeeding sinking fund payment, provided, however, that the Paying Agent shall from time to time upon receipt of a Company Order pay over and deliver to the Company any cash payment so being held by
          the Paying Agent upon delivery by the Company to the Registrar of Securities of that Series purchased by the Company having an unpaid principal amount equal to the cash payment required to be released to the Company.

       

      SECTION 11.03.  Redemption of Securities for Sinking Fund.

       

      Not less than [  ] days (unless otherwise indicated in the Board Resolution, supplemental indenture hereto or Officers' Certificate in
        respect of a particular Series of Securities) prior to each sinking fund payment date for any Series of Securities, the Company will deliver to the Trustee and the Paying Agent an Officers' Certificate specifying the amount of the next ensuing
        mandatory sinking fund payment for that Series pursuant to the terms of that Series, the portion thereof, if any, which is to be satisfied by payment of cash and the portion thereof, if any, which is to be satisfied by delivering and crediting of
        Securities of that Series pursuant to Section 11.02., and the optional amount, if any, to be added in cash to the next ensuing mandatory sinking fund payment, and the Company shall thereupon be obligated to pay the amount therein specified.  Not
        less than [  ] days (unless otherwise indicated in the Board Resolution, Officers' Certificate or supplemental indenture in respect of a particular Series of Securities) before each such sinking fund payment date the Trustee shall select the
        Securities to be redeemed upon such sinking fund payment date in the manner specified in Section 3.02 and cause notice of the redemption thereof to be given in the name of and at the expense of the Company in the manner provided in Section
        3.03.  Such notice having been duly given, the redemption of such Securities shall stated in Sections 3.04, 3.05 and 3.06.

       

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      IN WITNESS WHEREOF, the parties hereto have caused this Indenture to be duly executed as of the day and year first above written.

       

      

      

      

      

      

      

      

      

      EURONAV NV

      

      

      

      By:__________________________

      

      

      Name:

      Its:

      

      

      

      

      [                ]

      as Trustee

      

      

      By:__________________________

      

      

      Name:

      Its:

      

      

      

      

      By:__________________________

      

      

      Name:

      Its:

      

      

      

      

      [                   ]

      as Registrar and Paying Agent

      

      

      

      

      By:__________________________

      

      

      Name:

      Its:

      

      

      

      

      By:__________________________

      

      

      Name:

      Its:

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