Document:

Exhibit 4.5

 

BROKER WARRANT

 

THIS WARRANT AND THE SECURITIES ISSUABLE
UPON THE EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. THEY MAY NOT BE SOLD, OFFERED FOR
SALE, PLEDGED, HYPOTHECATED OR OTHERWISE TRANSFERRED EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES
ACT OF 1933, AS AMENDED, OR AN OPINION OF COUNSEL SATISFACTORY TO THE COMPANY THAT REGISTRATION IS NOT REQUIRED UNDER SUCH ACT
OR UNLESS SOLD IN ACCORDANCE WITH RULE 144 UNDER SUCH ACT.

 

	WARRANT NO. [  ]	NUMBER OF SHARES:  [  ]
	DATE OF ISSUANCE: [  ]	(subject to adjustment hereunder)
	EXPIRATION DATE: [  ]	 

 

WARRANT TO PURCHASE SHARES

OF COMMON STOCK OF

 

NEUROTROPE, INC.

 

This Warrant is issued
to [  ], or its registered assigns (including any successors or assigns, the “Warrantholder”), which is hereby
acknowledged by Neurotrope, Inc., a Nevada corporation (the “Company”).

 

		1.	EXERCISE OF WARRANT.

 

(a)         Number
and Exercise Price of Warrant Shares; Expiration Date. Subject to the terms and conditions set forth herein and set forth herein,
the Warrantholder is entitled to purchase from the Company up to [ ] shares of the Company’s Common Stock, $0.001 par value
per share (the “Common Stock”) (as adjusted from time to time pursuant to the provisions of this Warrant) (the
“Warrant Shares”), at a purchase price of $0.20 per share (the “Exercise Price”), on or before
5:00 p.m. New York City time on the fifth anniversary of the Date of Issuance (the “Expiration Date”) (subject
to earlier termination of this Warrant as set forth herein).

 

(b)        Method
of Exercise. While this Warrant remains outstanding and exercisable in accordance with Section 1(a) above, the Warrantholder
may exercise this Warrant in accordance with Section 5 herein, by either:

 

(1)         wire
transfer to the Company or cashier’s check drawn on a United States bank made payable to the order of the Company, or

 

(2)         exercising
of the right to credit the Exercise Price against the Fair Market Value of the Warrant Shares (as defined below) at the time of
exercise (the “Net Exercise”) pursuant to Section 1(c).

 

     

     

    

  

Notwithstanding anything
herein to the contrary, the Warrantholder shall not be required to physically surrender this Warrant to the Company until the Warrantholder
has purchased all of the Warrant Shares available hereunder and the Warrant has been exercised in full, in which case, the Warrantholder
shall surrender this Warrant to the Company for cancellation within three (3) trading days of the date the final Notice of Exercise
is delivered to the Company. Partial exercises of this Warrant resulting in purchases of a portion of the total number of Warrant
Shares available hereunder shall have the effect of lowering the outstanding number of Warrant Shares purchasable hereunder in
an amount equal to the applicable number of Warrant Shares purchased. The Warrantholder and the Company shall maintain records
showing the number of Warrant Shares purchased and the date of such purchases.

 

(c)        Net
Exercise. If the Company shall receive written notice from the Warrantholder at the time of exercise of this Warrant that the
holder elects to Net Exercise the Warrant, the Company shall deliver to such Warrantholder (without payment by the Warrantholder
of any exercise price in cash) that number of Warrant Shares computed using the following formula: 

 

Where

 

		X =	The number of Warrant Shares to be issued to the Warrantholder.

 

		Y=	The number of Warrant Shares purchasable under this Warrant
or, if only a portion of the Warrant is being exercised, the portion of the Warrant being cancelled (at the date of such calculation).

 

		A=	The Fair Market Value of one (1) share of Common Stock
on the trading date immediately preceding the date on which Warrantholder elects to exercise this Warrant.

 

		B=	The Exercise Price (as adjusted hereunder).

 

The “Fair
Market Value” of one share of Common Stock shall mean (x) the last reported sale price and, if there are no sales, the
last reported bid price, of the Common Stock on the business day prior to the date of exercise on the Trading Market on which the
Common Stock is then listed or quoted as reported by Bloomberg Financial Markets (or a comparable reporting service of national
reputation selected by the Company and reasonably acceptable to the holder if Bloomberg Financial Markets is not then reporting
sales prices of the Common Stock) (collectively, “Bloomberg”), (y) if the foregoing does not apply, the last
sales price of the Common Stock in the over-the-counter market on the pink sheets or bulletin board for such security as reported
by Bloomberg, and, if there are no sales, the last reported bid price of the Common Stock as reported by Bloomberg or, (z) if fair
market value cannot be calculated as of such date on either of the foregoing bases, the price determined in good faith by the Company’s
Board of Directors.

 

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“OTC Markets”
shall mean either OTC QX or OTC QB of the OTC Markets Group, Inc.

 

“Trading Market”
shall mean any of the following markets or exchanges on which the Common Stock is listed or quoted for trading on the date in question:
the NYSE MKT, the NASDAQ Capital Market, the NASDAQ Global Market, the NASDAQ Global Select Market, the New York Stock Exchange
or the OTC Markets (or any successors to any of the foregoing).

 

(d)        Deemed
Exercise. In the event that immediately prior to the close of business on the Expiration Date, the Fair Market Value of one
share of Common Stock (as determined in accordance with Section 1(c) above) is greater than the then applicable Exercise
Price, this Warrant shall be deemed to be automatically exercised on a net exercise issue basis pursuant to Section 1(c)
above, and the Company shall deliver the applicable number of Warrant Shares to the Warrantholder pursuant to the provisions of
Section 1(c) above and this Section 1(d).

 

		2.	CERTAIN ADJUSTMENTS.

 

(a)        Adjustment
of Number of Warrant Shares and Exercise Price. The number and kind of Warrant Shares purchasable upon exercise of this
Warrant and the Exercise Price shall be subject to adjustment from time to time as follows:

 

(1)         Subdivisions,
Combinations and Other Issuances. If the Company shall at any time after the Date of Issuance but prior to the Expiration Date
subdivide its shares of capital stock of the same class as the Warrant Shares, by split-up or otherwise, or combine such shares
of capital stock, or issue additional shares of capital stock as a dividend with respect to any shares of such capital stock, the
number of Warrant Shares issuable on the exercise of this Warrant shall forthwith be proportionately increased in the case of a
subdivision or stock dividend, or proportionately decreased in the case of a combination. Appropriate adjustments shall also be
made to the Exercise Price payable per share, but the aggregate Exercise Price payable for the total number of Warrant Shares purchasable
under this Warrant (as adjusted) shall remain the same. Any adjustment under this Section 2(a)(1) shall become effective
at the close of business on the date the subdivision or combination becomes effective, or as of the record date of such dividend,
or in the event that no record date is fixed, upon the making of such dividend.

 

(2)         Reclassification,
Reorganizations and Consolidation. In case of any reclassification, capital reorganization or change in the capital stock of
the Company (other than as a result of a subdivision, combination or stock dividend provided for in Section 2(a)(1) above)
that occurs after the Date of Issuance, then, as a condition of such reclassification, reorganization or change, lawful provision
shall be made, and duly executed documents evidencing the same from the Company or its successor shall be delivered to the Warrantholder,
so that the Warrantholder shall thereafter have the right at any time prior to the expiration of this Warrant to purchase, at a
total price equal to that payable upon the exercise of this Warrant, the kind and amount of shares of stock and/or other securities
or property (including, if applicable, cash) receivable in connection with such reclassification, reorganization or change by a
holder of the same number and type of securities as were purchasable as Warrant Shares by the Warrantholders immediately prior
to such reclassification, reorganization or change. In any such case appropriate provisions shall be made with respect to the rights
and interest of the Warrantholder so that the provisions hereof shall thereafter be applicable with respect to any shares of stock
or other securities or property deliverable upon exercise hereof, and appropriate adjustments shall be made to the Exercise Price
payable hereunder, provided the aggregate Exercise Price shall remain the same (and, for the avoidance of doubt, this Warrant shall
be exclusively exercisable for such shares of stock and/or other securities or property from and after the consummation of such
reclassification or other change in the capital stock of the Company).

 

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(b)        Notice
to Warrantholder. If, while this Warrant is outstanding, the Company (i) declares a dividend or any other distribution
of cash, securities or other property in respect of its Common Stock, including, without limitation, any granting of rights or
warrants to subscribe for or purchase any capital stock of the Company or any subsidiary, (ii) authorizes or approves, enters
into any agreement contemplating or solicits stockholder approval for any Change of Control or (iii) authorizes the voluntary
dissolution, liquidation or winding up of the affairs of the Company, then the Company shall deliver to the Warrantholder a notice
of such transaction at least ten (10) business days prior to the applicable record or effective date on which a person would need
to hold Common Stock in order to participate in or vote with respect to such transaction; provided, however, that the failure to
deliver such notice or any defect therein shall not affect the validity of the corporate action required to be described in such
notice.

 

(c)        Calculations.
All calculations under this Section 2 shall be made to the nearest cent or the nearest whole share, as the case may be.
For purposes of this Section 2, the number of shares of Common Stock deemed to be issued and outstanding as of a given date
shall be the sum of the number of shares of Common Stock (excluding treasury shares, if any) issued and outstanding.

 

		(d)	Treatment of Warrant upon a Change of Control.

 

(1)         If,
at any time while this Warrant is outstanding, the Company consummates a Change of Control, then a holder shall have the right
thereafter to receive, upon exercise of this Warrant, the same amount and kind of securities, cash or property as it would have
been entitled to receive upon the occurrence of such Change of Control if it had been, immediately prior to such Change of Control,
a holder of the number of Warrant Shares then issuable upon exercise in full of this Warrant (the “Alternate Consideration”).
The Company shall not effect any such Change of Control unless prior to or simultaneously with the consummation thereof, any successor
to the Company, surviving entity or the corporation purchasing or otherwise acquiring such assets or other appropriate corporation
or entity shall assume the obligation to deliver to the holder, such Alternate Consideration as, in accordance with the foregoing
provisions, the holder may be entitled to purchase, and the other obligations under this Warrant.

 

(2)         As
used in this Warrant, a “Change of Control” shall mean (i) a merger or consolidation of the Company with another
corporation (other than a merger effected exclusively for the purpose of changing the domicile of the Company), (ii) the sale,
assignment, transfer, conveyance or other disposal of all or substantially all of the properties or assets or all or a majority
of the outstanding voting shares of capital stock of the Company, (iii) a purchase, tender or exchange offer accepted by the holders
of a majority of the outstanding voting shares of capital stock of the Company, or (iv) a “person” or “group”
(as these terms are used for purposes of Section 13(d) and 14(d) of the Securities Exchange Act of 1934, as amended (the “Exchange
Act”)) is or shall become the “beneficial owner” (as defined in Rule 13d-3 under the Exchange Act), directly
or indirectly at least a majority of the voting power of the capital stock of the Company.

 

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3.          NO
FRACTIONAL SHARES. No fractional Warrant Shares or scrip representing fractional shares will be issued upon exercise of this Warrant.
In lieu of any fractional shares which would otherwise be issuable, the Company shall pay cash equal to the product of such fraction
multiplied by the Fair Market Value of one Warrant Share.

 

4.          NO
STOCKHOLDER RIGHTS. Until the exercise of this Warrant or any portion of this Warrant, the Warrantholder shall not have, nor exercise,
any rights as a stockholder of the Company (including without limitation the right to notification of stockholder meetings or the
right to receive any notice or other communication concerning the business and affairs of the Company) except as provided in Section
8 below.

 

		5.	MECHANICS OF EXERCISE.

 

(a)        Delivery
of Warrant Shares Upon Exercise. This Warrant may be exercised by the holder hereof, in whole or in part, by delivering to
the Company (or such other office or agency of the Company as it may designate by notice in writing to the registered Warrantholder
at the address of the Warrantholder appearing on the books of the Company) of a duly executed copy of the Notice of Exercise in
the form attached hereto as Exhibit A by facsimile or e-mail attachment and paying the Exercise Price (unless the Warrantholder
has elected to Net Exercise) then in effect with respect to the number of Warrant Shares as to which the Warrant is being exercised.
This Warrant shall be deemed to have been exercised immediately prior to the close of business on the date of the delivery to the
Company of the Notice of Exercise as provided above, and the person entitled to receive the Warrant Shares issuable upon such exercise
shall be treated for all purposes as the holder of such shares of record as of the close of business on such date. Warrant Shares
purchased hereunder shall be transmitted by the Company’s transfer agent to the holder by crediting the account of the holder’s
prime broker with The Depository Trust Company through its Deposit or Withdrawal at Custodian system (“DWAC”)
if the Company is then a participant in such system and either (A) there is an effective registration statement permitting the
issuance of the Warrant Shares to or resale of the Warrant Shares by the holder or (B) the shares are eligible for resale by the
holder without volume or manner-of-sale limitations pursuant to Rule 144, and otherwise by physical delivery to the address specified
by the holder in the Notice of Exercise by the end of the day on the date that is three (3) trading days from the delivery to the
Company of the Notice of Exercise and payment of the aggregate Exercise Price (unless exercised by means of a cashless exercise
pursuant to Section 1(c)). The Warrant Shares shall be deemed to have been issued, and the holder or any other person so
designated to be named therein shall be deemed to have become a holder of record of such shares for all purposes, as of the date
the Warrant has been exercised, with payment to the Company of the Exercise Price (or by Net Exercise) and all taxes required to
be paid by the holder, if any, prior to the issuance of such shares, having been paid.

 

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(b)        Rescission
Rights. If the Company fails to cause the transfer agent to transmit to the Warrantholder the Warrant Shares pursuant to Section
5(a) by the Warrant Share Delivery Date, then the Warrantholder will have the right to rescind such exercise.

 

(c)        Warrantholder’s
Exercise Limitations. A holder shall not have the right to exercise this Warrant, pursuant to Section 1 or otherwise,
to the extent that after giving effect to such issuance after exercise as set forth on the applicable Notice of Exercise, the holder
(together with the holder’s affiliates, and any other persons acting as a group together with the holder or any of the holder’s
affiliates), would beneficially own in excess of the Beneficial Ownership Limitation (as defined below).  For purposes of
the foregoing sentence, the aggregate number of shares of Common Stock beneficially owned by the holder and its affiliates shall
include the number of shares of Common Stock issuable upon exercise of this Warrant with respect to which such determination is
being made, but shall exclude the number of shares of Common Stock which would be issuable upon (i) exercise of the remaining,
nonexercised portion of this Warrant beneficially owned by the holder or any of its affiliates and (ii) exercise or conversion
of the unexercised or nonconverted portion of any other securities of the Company (including, without limitation, any other convertible
notes or convertible preferred stock or warrants) subject to a limitation on conversion or exercise analogous to the limitation
contained herein beneficially owned by the holder or any of its affiliates.  Except as set forth in the preceding sentence,
for purposes of this section, beneficial ownership shall be calculated in accordance with Section 13(d) of the Exchange Act and
the rules and regulations promulgated thereunder, it being acknowledged by the holder that the Company is not representing to the
holder that such calculation is in compliance with Section 13(d) of the Exchange Act and the holder is solely responsible for any
schedules required to be filed in accordance therewith. To the extent that the limitation contained in this Section 5(c)
applies, the determination of whether this Warrant is exercisable (in relation to other securities owned by the holder together
with any affiliates) and of which portion of this Warrant is exercisable shall be in the sole discretion of the holder, and the
submission of a Notice of Exercise shall be deemed to be the holder’s determination of whether this Warrant is exercisable
(in relation to other securities owned by the holder together with any affiliates) and of which portion of this Warrant is exercisable,
in each case subject to the Beneficial Ownership Limitation, and the Company shall have no obligation to verify or confirm the
accuracy of such determination and shall have no liability for exercise of the Warrant that are not in compliance with the Beneficial
Ownership Limitation. In addition, a determination as to any group status as contemplated above shall be determined in accordance
with Section 13(d) of the Exchange Act and the rules and regulations promulgated thereunder. For purposes of this Section 5(c),
in determining the number of outstanding shares of Common Stock, a holder may rely on the number of outstanding shares of Common
Stock as reflected in (A) the Company’s most recent periodic or annual report filed with the U.S. Securities and Exchange
Commission, as the case may be, (B) a more recent public announcement by the Company or (C) a more recent written notice by the
Company or the Company’s transfer agent setting forth the number of shares of Common Stock outstanding.  Upon the written
request of a holder, the Company shall within two (2) trading days confirm in writing to the holder the number of shares of Common
Stock then outstanding.  In any case, the number of outstanding shares of Common Stock shall be determined after giving effect
to the conversion or exercise of securities of the Company, including this Warrant, by the holder or its affiliates since the date
as of which such number of outstanding shares of Common Stock was reported. The “Beneficial Ownership Limitation”
shall be 9.99% of the number of shares of the Common Stock outstanding immediately after giving effect to the issuance of shares
of Common Stock issuable upon exercise of this Warrant. Any such increase or decrease will not be effective until the 61st day
after such notice is delivered to the Company. The provisions of this paragraph shall be construed and implemented in strict conformity
with the terms of this Section 5(c) to correct this paragraph (or any portion hereof) which may be defective or inconsistent
with the intended Beneficial Ownership Limitation herein contained or to make changes or supplements necessary or desirable to
properly give effect to such limitation. The limitations contained in this paragraph shall apply to a successor holder of this
Warrant.

 

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6.          CERTIFICATE
OF ADJUSTMENT. Whenever the Exercise Price or number or type of securities issuable upon exercise of this Warrant is adjusted,
as herein provided, the Company shall, at its expense, promptly deliver to the Warrantholder a certificate of an officer of the
Company setting forth the nature of such adjustment and showing in detail the facts upon which such adjustment is based.

 

		7.	COMPLIANCE WITH SECURITIES LAWS.

 

(a)        The
Warrantholder understands that this Warrant and the Warrant Shares are characterized as “restricted securities” under
the federal securities laws inasmuch as they are being acquired from the Company in a transaction not involving a public offering
and that under such laws and applicable regulations this Warrant and the Warrant Shares may be resold without registration under
the Securities Act only in certain limited circumstances. In this connection, the Warrantholder represents that it is familiar
with Rule 144 under the Securities Act, as presently in effect, and understands the resale limitations imposed thereby and by the
Securities Act.

 

(b)        Prior
and as a condition to the sale or transfer of the Warrant Shares issuable upon exercise of this Warrant, the Warrantholder shall
furnish to the Company such certificates, representations, agreements and other information, including an opinion of counsel, as
the Company or the Company’s transfer agent reasonably may require to confirm that such sale or transfer is being made pursuant
to an exemption from, or in a transaction not subject to, the registration requirements of the Securities Act, unless such Warrant
Shares are being sold or transferred pursuant to an effective registration statement.

 

(c)        The
Warrantholder acknowledges that the Company may place a restrictive legend on the Warrant Shares issuable upon exercise of this
Warrant in order to comply with applicable securities laws, in substantially the following form and substance, unless such Warrant
Shares are otherwise freely tradable under Rule 144 of the Securities Act:

 

“THE
SECURITIES EVIDENCED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE U.S. SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES
ACT”), OR ANY OTHER APPLICABLE SECURITIES LAWS AND HAVE BEEN ISSUED IN RELIANCE UPON AN EXEMPTION FROM THE REGISTRATION REQUIREMENTS
OF THE SECURITIES ACT AND SUCH OTHER SECURITIES LAWS. NEITHER THIS SECURITY NOR ANY INTEREST OR PARTICIPATION HEREIN MAY BE REOFFERED,
SOLD, ASSIGNED, TRANSFERRED, PLEDGED, ENCUMBERED, HYPOTHECATED OR OTHERWISE DISPOSED OF, EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION
STATEMENT UNDER THE SECURITIES ACT OR PURSUANT TO A TRANSACTION WHICH IS EXEMPT FROM, OR NOT SUBJECT TO, SUCH REGISTRATION, IN
EACH CASE IN ACCORDANCE WITH ALL APPLICABLE SECURITIES LAWS, AND IN THE CASE OF A TRANSACTION EXEMPT FROM, OR NOT SUBJECT TO, SUCH
REGISTRATION, UNLESS THE COMPANY HAS RECEIVED AN OPINION OF COUNSEL REASONABLY SATISFACTORY TO IT THAT SUCH TRANSACTION DOES NOT
REQUIRE REGISTRATION UNDER THE SECURITIES ACT AND SUCH OTHER APPLICABLE LAWS.”

 

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8.          REPLACEMENT
OF WARRANTS. On receipt of evidence reasonably satisfactory to the Company of the loss, theft, destruction or mutilation of this
Warrant and, in the case of any such loss, theft or destruction of this Warrant, on delivery of an indemnity agreement reasonably
satisfactory in form and amount to the Company or, in the case of any such mutilation, on surrender and cancellation of such Warrant,
the Company at its expense will execute and deliver, in lieu thereof, a new Warrant of like tenor.

 

9.          NO
IMPAIRMENT. Except to the extent as may be waived by the holder of this Warrant, the Company will not, by amendment of its charter
or through a Change of Control, dissolution, sale of assets or any other voluntary action, avoid or seek to avoid the observance
or performance of any of the terms of this Warrant, but will at all times in good faith assist in the carrying out of all such
terms and in the taking of all such action as may be necessary or appropriate in order to protect the rights of the Warrantholder
against impairment.

 

10.        TRADING
DAYS. If the last or appointed day for the taking of any action or the expiration of any right required or granted herein shall
be other than a day on which the Common Stock is traded on the Trading Market, then such action may be taken or such right may
be exercised on the next succeeding day on which the Common Stock is so traded.

 

		11.	TRANSFERS; EXCHANGES.

 

(a)        Subject
to compliance with applicable federal and state securities laws and Section 7 hereof, this Warrant may be transferred by
the Warrantholder to any Affiliate (as defined below) with respect to any or all of the Warrant Shares purchasable hereunder (a
“Permitted Transfer”). For a transfer of this Warrant as an entirety by the Warrantholder, upon surrender of
this Warrant to the Company, together with the Notice of Assignment in the form attached hereto as Exhibit B duly completed
and executed on behalf of the Warrantholder, the Company shall issue a new Warrant of the same denomination to the assignee. For
a transfer of this Warrant with respect to a portion of the Warrant Shares purchasable hereunder, upon surrender of this Warrant
to the Company, together with the Notice of Assignment in the form attached hereto as Exhibit B duly completed and executed
on behalf of the Warrantholder, the Company shall issue a new Warrant to the assignee, in such denomination as shall be requested
by the Warrantholder, and shall issue to the Warrantholder a new Warrant covering the number of shares in respect of which this
Warrant shall not have been transferred. The term “Affiliate” as used herein means, with respect to any person,
any other person that, directly or indirectly through one or more intermediaries, controls, is controlled by or is under common
control with such person, and any officers, employees or partners of the Warrantholder.

 

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(b)       Upon
any Permitted Transfer, this Warrant is exchangeable, without expense, at the option of the Warrantholder, upon presentation and
surrender hereof to the Company for other warrants of different denominations entitling the holder thereof to purchase in the aggregate
the same number of shares of Common Stock purchasable hereunder. This Warrant may be divided or combined with other warrants that
carry the same rights upon presentation hereof at the principal office of the Company together with a written notice specifying
the denominations in which new warrants are to be issued to the Warrantholder and signed by the Warrantholder hereof. The term
“Warrants” as used herein includes any warrants into which this Warrant may be divided or exchanged.

 

12.       AUTHORIZED
SHARES. The Company covenants that, during the period the Warrant is outstanding, it will reserve from its authorized and unissued
Common Stock a sufficient number of shares to provide for the issuance of the Warrant Shares upon the exercise of any purchase
rights under this Warrant. The Company further covenants that its issuance of this Warrant shall constitute full authority to its
officers who are charged with the duty of issuing the necessary Warrant Shares upon the exercise of the purchase rights under this
Warrant. The Company will take all such reasonable action as may be necessary to assure that such Warrant Shares may be issued
as provided herein without violation of any applicable law or regulation, or of any requirements of the Trading Market upon which
the Common Stock may be quoted or listed. The Company covenants that all Warrant Shares which may be issued upon the exercise of
the purchase rights represented by this Warrant will, upon exercise of the purchase rights represented by this Warrant and payment
for such Warrant Shares in accordance herewith, be duly authorized, validly issued, fully paid and nonassessable and free from
all taxes, liens and charges created by the Company in respect of the issue thereof (other than taxes in respect of any transfer
occurring contemporaneously with such issue).

 

		13.	MISCELLANEOUS.

 

(a)        This
Agreement shall be governed by and construed in accordance with the laws of the United States of America and the State of New York,
both substantive and remedial, without regard to New York conflicts of law principles. Any judicial proceeding brought under this
Agreement or any dispute arising out of this Agreement or any matter related hereto shall be brought in the courts of the State
of New York, New York County, or in the United States District Court for the Southern District of New York.

 

(b)        All
notices, requests, consents and other communications hereunder shall be in writing, shall be sent by confirmed facsimile or electronic
mail, or mailed by first-class registered or certified airmail, or nationally recognized overnight express courier, postage prepaid,
and shall be deemed given when so sent in the case of facsimile or electronic mail transmission, or when so received in the case
of mail or courier, and addressed as follows: (a) if to the Company, at ) if to the Company, at Neurotrope, Inc., 205 East 42nd
Street, 16th Floor, New York, NY 10017 Attn: Mr. Robert Weinstein, e-mail: rweinstein@neurotropebioscience.com; with
a copy to (which shall not constitute notice) Mintz, Levin, Cohn, Ferris Glovsky & Popeo, PC 666 Third Avenue, New York, NY
10017, Attn: Jeffrey Schultz, Esq., e-mail: jschultz@mintz.com and (b) if to the Warrantholder, at such address or addresses (including
copies to counsel) as may have been furnished by the Warrantholder to the Company in writing.

 

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(c)       The
invalidity or unenforceability of any provision hereof shall in no way affect the validity or enforceability of any other provisions.

 

[Signature Page Follows]

 

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IN WITNESS WHEREOF,
this Common Stock Purchase Warrant is issued effective as of the date first set forth above.

 

	 	NEUROTROPE, INC.
	 	 	 
	 	By:	 
	 	Name:	Mr. Robert Weinstein
	 	Title:	Chief Financial Officer

 

[Signature Page to Warrant No. [ ]

 

     

     

    

 

EXHIBIT A

 

NOTICE OF EXERCISE

(To be signed only upon exercise of Warrant)

 

To: Neurotrope, Inc.

 

The undersigned, the
Warrantholder of the attached Warrant, hereby irrevocably elects to exercise the purchase right represented by such Warrant for,
and to purchase thereunder, __________________________ (________) shares of Common Stock of Neurotrope, Inc. and (choose one)

 

__________ herewith
makes payment of ___________________________ Dollars ($_________) thereof

 

or

 

__________ elects to
Net Exercise the Warrant pursuant to Section 1(b)(2) thereof.

 

The undersigned requests
that the certificates or book entry position evidencing the shares to be acquired pursuant to such exercise be issued in the name
of, and delivered to __________________________________________, whose address is _________________________________________       ___________________________________________________________.

 

By its signature below
the undersigned hereby represents and warrants that it is an “accredited investor” as defined in Rule 501(a) of Regulation
D promulgated under the Securities Act of 1933, as amended, and agrees to be bound by the terms and conditions of the attached
Warrant as of the date hereof, including Section 7 thereof.

 

	DATED:	 	 	 
	 	 	 
	 	 	(Signature must conform in all
	 	 	respects to name of the Warrantholder
	 	 	as specified on the face of the
	 	 	Warrant)
	 	 	 
	 	 	 
	 	 	[___________]

 

	 	Address:	 
	 	 
	 	 

  

     

     

    

  

EXHIBIT B

 

NOTICE OF ASSIGNMENT FORM

 

FOR VALUE RECEIVED,
[_________] (the “Assignor”) hereby sells, assigns and transfers all of the rights of the undersigned Assignor
under the attached Warrant with respect to the number of shares of common stock of Neurotrope, Inc. (the “Company”)
covered thereby set forth below, to the following “Assignee” and, in connection with such transfer, represents
and warrants to the Company that the transfer is in compliance with Section 7 of the Warrant and applicable federal and
state securities laws:

 

	NAME OF ASSIGNEE	 	ADDRESS/FAX NUMBER
	 	 	 
	Number of shares:	 	 	 
	 	 	 
	Dated:	 	 	Signature:	 
	 	 	 
	 	 	Witness:	 

 

ASSIGNEE ACKNOWLEDGMENT

 

The undersigned Assignee
acknowledges that it has reviewed the attached Warrant and by its signature below it hereby represents and warrants that it is
an “accredited investor” as defined in Rule 501(a) of Regulation D promulgated under the Securities Act of 1933, as
amended, and agrees to be bound by the terms and conditions of the Warrant as of the date hereof, including Section 7 thereof.

 

	 	 	Signature:	 
	 	 	 
	 	 	By: 	 
	 	 	Its:	 

 

	Address:Exhibit 10.1

 

SECURITIES PURCHASE AGREEMENT

 

This SECURITIES
PURCHASE AGREEMENT (the “Agreement”), dated as of November 17, 2016, is by and among Neurotrope, Inc., a
Nevada corporation (the “Company”), and each of the investors listed on the Schedule of Buyers attached hereto
(individually, a “Buyer” and collectively, the “Buyers”).

 

RECITALS

 

A.           Each
Buyer wishes to purchase, and the Company wishes to sell, upon the terms and conditions stated in this Agreement, (i) the aggregate
number of shares of Common Stock set forth opposite such Buyer’s name in column (3) on the Schedule of Buyers (which shall
collectively be referred to herein as the “Common Shares”) and (ii) a Series F warrant to initially acquire
at an exercise price of $0.40 per share up to the aggregate number of shares of Common Stock set forth opposite such Buyer’s
name in column (4) on the Schedule of Buyers, in the form attached hereto (individually, a “Warrant” and, collectively,
the “Warrants”) (as exercised, collectively, the “Warrant Shares”).

 

B.           The
Common Shares, the Warrants and the Warrant Shares are collectively referred to herein as the “Securities.”

 

C.           Capitalized
terms used herein shall have the meanings set forth in the Schedule of Definitions or as otherwise defined herein.

 

D.           The
parties hereto each understand that this Securities Purchase Agreement and the purchase and sale contemplated hereby is unconditional
and binding on all parties hereto. 

 

AGREEMENT

 

NOW, THEREFORE, in
consideration of the premises and the mutual covenants contained herein and for other good and valuable consideration, the receipt
and sufficiency of which are hereby acknowledged, the Company and each Buyer hereby agree as follows:

 

		1.	PURCHASE AND SALE OF COMMON
SHARES AND WARRANTS.

 

(a)          Purchase
of Common Shares and Warrants. Subject to the satisfaction (or waiver) of the conditions set forth in Section 6 below, the
Company shall issue and sell to each Buyer, and each Buyer severally, but not jointly, shall purchase from the Company on each
Closing Date (as defined below), (i) the number of Common Shares as is set forth opposite such Buyer’s name in column (3)
on the Schedule of Buyers and (ii) Warrants to initially acquire up to the aggregate number of Warrant Shares as is set forth
opposite such Buyer’s name in column (4) on the Schedule of Buyers. Each Buyer buying Common Shares and Warrants at the
Initial Closing or the Final Closing, if such Buyer so chooses, shall deliver on or before the Initial Closing or Final Closing,
as applicable the Purchase Price in full to Delaware Trust Company (the “Escrow Agent”) by check to the address
listed below or via wire transfer of immediately available funds pursuant to the wire instructions below. Each Buyer understands
that the applicable Purchase Price (defined below) will be held in escrow until the applicable Closing on the sale of the Common
Shares and Warrants has occurred, and that such amount will be returned to such Buyer, without interest, if (i) a minimum of $8,000,000
of Common Shares and Warrants are not sold by the Company to the Buyers on or before November 30, 2016, or (ii) a court of competent
jurisdiction issues a final and non-appealable judgment, order, decree or award ordering the escrow agent to deliver the Purchase
Price.

 

     

     

    

 

Address for Payment
by Check: 

Attention:

Reference: 

MUST INCLUDE BUYER’S
NAME

 

Wire Instructions:

Account Name:

Account Number: 

Reference: 

MUST INCLUDE BUYER’S
NAME

 

(b)          Purchase
Price. The aggregate purchase price for the Common Shares and related Warrants to be purchased by each Buyer (the “Purchase
Price”) shall be the amount set forth opposite such Buyer’s name in column (5) on the Schedule of Buyers which
shall be equal to the amount of $0.20 per Common Share and related Warrants.

 

		(c)	Closing.

 

		(i)	The initial closing (the “Closing”)
of the purchase of the Common Shares and Warrants by the Buyers shall occur at the offices of Mintz, Levin, Cohn, Ferris, Glovsky
and Popeo, P.C. (“Mintz”), 666 Third Avenue, New York, NY 10017 or such other location as agreed to by the
Company. The date and time of the Initial Closing (the “Initial Closing Date”) shall be 10:00 a.m.,
New York time, on the first (1st) Business Day on which the closing conditions set forth in Section 6 below are satisfied
or waived (or such later date as is mutually agreed to by the Company and each Buyer) provided that such date shall not be later
than the third (3rd) Trading Day after the date hereof, but in any event no later than 5:00 pm, New York time, on November
22, 2016. A minimum of $8,000,000 of Common Shares and Warrants must be sold at the Initial Closing. In the event there is more
than one closing as described in Section 1(c)(ii) below, the term “Closing” shall apply to each such closing
unless otherwise specified and the term “Closing Date” shall apply to each such closing date unless otherwise
specified. As used in this Agreement, “Business Day” means any day other than a Saturday, Sunday or other day
on which commercial banks in New York, New York are authorized or required by law to remain closed.

 

		(ii)	After the Initial Closing, the Company may sell, in one
additional Closing (the “Final Closing”) on the same terms and conditions as those contained in this Agreement,
additional Common Shares and Warrants (collectively, the “Additional Securities”), to one or more Buyers (each,
an “Additional Buyer,” and, collectively, the “Additional Buyers”) provided that each Additional
Buyer shall become a party to the Transaction Documents by executing and delivering either an applicable adoption agreement, a
counterpart signature page or omnibus signature page to each of the Transaction Documents. The Schedule of Buyers attached hereto
shall be updated to reflect the names and addresses of the Additional Buyers and the number of Additional Securities purchased
at the Final Closing.

 

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(d)          Form
of Payment; Deliveries. On or before the Initial Closing Date or the date of the Final Closing, as applicable, each Buyer purchasing
Common Shares and Warrants at such Closing shall pay its respective Purchase Price to the Company or by delivering its Purchase
Price to the Escrow Agent pursuant to Section 1(a). On each applicable Closing Date, (i) the Escrow Agent shall deliver on behalf
of each Buyer acquiring Common Shares and the related Warrants at the applicable Closing the respective Purchase Price to the Company
for the Common Shares and related Warrants to be issued and sold to such Buyer at the Closing pursuant to Section 1(a) above. On
each Closing Date, the Company shall cause Philadelphia Stock Transfer, Inc. (together with any subsequent transfer agent, the
“Transfer Agent”) to deliver stock certificates representing such aggregate number of Common Shares that such
Buyer is purchasing at such Closing as is set forth opposite such Buyer’s name in column (3) on the Schedule of Buyers. Within
five business days of the applicable Closing Date, the Company shall deliver, or cause to be delivered warrant certificates, in
the form attached hereto as Exhibit A, pursuant to which such Buyer shall have the right to initially acquire
up to the number of Warrant Shares as is set forth opposite such Buyer’s name in column (4) on the Schedule of Buyers.

 

		2.	BUYER’S REPRESENTATIONS
AND WARRANTIES.

 

Each Buyer, severally
and not jointly, represents and warrants to the Company with respect to only itself that:

 

(a)          Organization;
Authority. Such Buyer is an entity duly organized, validly existing and in good standing under the laws of the jurisdiction
of its organization with the requisite power and authority to enter into and to consummate the transactions contemplated by this
Agreement and otherwise to carry out its obligations hereunder and thereunder.

 

(b)          Validity;
Enforcement. This Agreement has been duly and validly authorized, executed and delivered on behalf of such Buyer and constitutes
the legal, valid and binding obligations of such Buyer enforceable against such Buyer in accordance with their respective terms,
except as such enforceability may be limited by general principles of equity or applicable bankruptcy, insolvency, reorganization,
moratorium, liquidation and other similar laws relating to, or affecting generally, the enforcement of applicable creditors’
rights and remedies.

 

(c)          No
Conflicts. The execution, delivery and performance by such Buyer of this Agreement and the consummation by such Buyer of the
transactions contemplated hereby will not (i) result in a violation of the organizational documents of such Buyer, (ii) conflict
with, or constitute a default (or an event which with notice or lapse of time or both would become a default) under, or give to
others any rights of termination, amendment, acceleration or cancellation of, any agreement, indenture or instrument to which such
Buyer is a party, or (iii) result in a violation of any law, rule, regulation, order, judgment or decree (including federal and
state securities laws) applicable to such Buyer, except in the case of clauses (ii) and (iii) above, for such conflicts, defaults,
rights or violations which would not, individually or in the aggregate, reasonably be expected to have a material adverse effect
on the ability of such Buyer to perform its obligations hereunder.

 

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(d)          Certain
Trading Activities. Other than with respect to the transactions contemplated herein, neither such Buyer nor, to Buyer’s
Knowledge (as defined below), any Affiliate of such Buyer which (x) had Knowledge of the transactions contemplated hereby, (y)
has or shares discretion relating to such Buyer’s investments or trading or information concerning such Buyer’s investments,
including in respect of the Securities, and (z) is subject to such Buyer’s review or input concerning such Affiliate’s
investments or trading (collectively, “Trading Affiliates”) has not directly or indirectly, nor has any Person
(as such term is defined in Section 3(r)) acting on behalf of or pursuant to any understanding with such Buyer or, to Buyer’s
Knowledge, Trading Affiliate, engaged in any transactions in the securities of the Company (including, without limitation, any
Short Sales (as defined below) involving the Company’s securities) during the period commencing as of the time that such
Buyer was first contacted by the Company or any other Person regarding this investment in the Company and ending immediately prior
to the execution of this Agreement by such Buyer (it being understood and agreed that for all purposes of this Agreement, and without
implication that the contrary would otherwise be true, neither transactions nor purchases nor sales shall include
the location and/or reservation of borrowable shares of Common Stock). “Short Sales” means all “short
sales” as defined in Rule 200 promulgated under Regulation SHO under the Securities Exchange Act of 1934, as amended (the
“1934 Act”). As used in this Agreement, “Knowledge” or “Knowingly” means
with respect to any Person, what such Person actually knows or reasonably should know, and, in the case of a corporation or other
entity, what its executive officers actually know or reasonably should know.

 

(e)          Transfer
or Resale. Such Buyer understands that except as provided in the Registration Rights Agreement entered into among the Company
and the Buyers as of the date hereof, the (“Registration Rights Agreement”), this Agreement and Section 4(e)
hereof: (i) the Securities have not been and are not being registered under the 1933 Act or any state securities laws, and may
not be offered for sale, sold, assigned or transferred unless (A) subsequently registered thereunder, or (B) such Buyer shall have
delivered to the Company (if requested by the Company) an opinion of counsel to such Buyer, in substance which shall be reasonably
acceptable to the Company, to the effect that such Securities to be sold, assigned or transferred may be sold, assigned or transferred
pursuant to an exemption from such registration; (ii) any sale of the Securities made in reliance on Rule 144 or Rule 144A promulgated
under the 1933 Act (or a successor rule thereto) (collectively, “Rule 144”) may be made only in accordance with
the terms of Rule 144, and further, if Rule 144 is not applicable, any resale of the Securities under circumstances in which the
seller (or the Person (as defined below) through whom the sale is made) may be deemed to be an underwriter (as that term is defined
in the 1933 Act) may require compliance with some other exemption under the 1933 Act or the rules and regulations of the SEC promulgated
thereunder; and (iii) neither the Company nor any other Person is under any obligation to register the Securities under the 1933
Act or any state securities laws or to comply with the terms and conditions of any exemption thereunder.

 

(f)          Own
Account. Such Buyer understands that (i) the Securities are “restricted securities” and that the offer and sale
of the Securities have not been registered under the 1933 Act or any applicable state securities law and (ii) the Securities must
be held indefinitely unless a subsequent disposition thereof is registered under the Securities Act or is exempt from such registration.
Such Buyer is acquiring the Securities as principal for its own account and not with a view to or for distributing or reselling
such Securities or any part thereof in violation of the 1933 Act or any applicable state securities law, has no present intention
of distributing any of such Securities in violation of the 1933 Act or any applicable state securities law and has no direct or
indirect arrangement or understanding with any other Persons regarding the distribution of such Securities (this representation
and warranty not limiting such Buyer’s right to sell the Securities pursuant to the Registration Statement (as defined in
the Registration Rights Agreement) or otherwise in compliance with applicable federal and state securities laws) in violation of
the 1933 Act or any applicable state securities law. Such Buyer is acquiring the Securities hereunder in the ordinary course of
its business.

 

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(g)          Buyer
Status. At the time such Buyer was offered the Securities, it was, and at the date hereof it is, and on each date on which
it exercises any Warrants it: (i) will be either (A) an “accredited investor” as defined in Rule 501(a)(1), (a)(2),
(a)(3), (a)(7) or (a)(8) under the 1933 Act or (B) a “qualified institutional buyer” as defined in Rule 144A(a) under
the 1933 Act or (ii) is not a “U.S. Person” (as defined in Regulation S promulgated under the 1933 Act). If such Buyer
is not a U.S. Person, such Buyer further represents and warrants that (1) such Buyer has not subscribed for the Units for the account
of any Person who is a U.S. Person, (2) the offer and sale of the Units to such Buyer constitute an “Offshore Transaction”
(as defined in Rule 902 promulgated under the 1933 Act), and (3) such Buyer will not resell the Securities, other than in accordance
with this Agreement, the Transaction Documents, the provisions of Regulation S promulgated under the 1933 Act (Rules 901 through
905), pursuant to registration under the 1933 Act or pursuant to any other available exemption from registration. Such Buyer further
agrees that it will not take any action that could have an adverse effect on the availability of the exemption from registration
provided, in the case of a Buyer covered by clause (i) above, by Regulation D promulgated under the 1933 Act or, in the case of
a Buyer covered by clause (ii) above, by Regulation S promulgated under the 1933 Act, with respect to the offer and sale of the
Units. Such Buyer is not required to be registered as a broker-dealer under Section 15 of the 1934 Act, or a member of the Financial
Industry Regulatory Authority, Inc. or an entity engaged in the business of being a broker dealer. Such Buyer is not affiliated
with any broker dealer registered under Section 15(a) of the 1934 Act, or a member of the Financial Industry Regulatory Authority,
Inc. or an entity engaged in the business of being a broker dealer.

 

(h)          Experience
of Such Buyer. Such Buyer, either alone or together with its representatives, has such knowledge, sophistication and experience
in business and financial matters so as to be capable of evaluating the merits and risks of the prospective investment in the Securities
and has so evaluated the merits and risks of such investment. Such Buyer is able to bear the economic risk of an investment in
the Securities and is able to afford a complete loss of such investment. Such Buyer understands that nothing in the Agreement or
any other materials presented to the Buyer in connection with the purchase and sale of the Securities constitutes legal, tax or
investment advice. Such Buyer acknowledges that it must rely on legal, tax and investment advisors of its own choosing in connection
with its purchase of the Securities.

 

(i)          General
Solicitation. Such Buyer is not purchasing the Securities as a result of any advertisement, article, notice or other communication
regarding the Securities published in any newspaper, magazine or similar media or broadcast over television or radio, disseminated
over the Internet or presented at any seminar or, to such Buyer's knowledge, any other general solicitation or general advertisement.

 

(j)          Independent
Investigation. Such Buyer, in acquiring the Securities, has relied solely upon an independent investigation made by such Buyer
and his or her representatives, if any. Prior to the date hereof, such Buyer has been given the opportunity to ask questions of,
and receive answers from, representatives of the Company and the Subsidiary regarding the Company’s and the Subsidiary’s
management, finances, and business. Such Buyer also has access to or has received the SEC Documents and has carefully reviewed
the SEC Documents, including the risk factor disclosure contained therein relating to the high degree of risk involved in investing
in the Company’s securities, and is knowledgeable about the affairs of the Company and the Subsidiary. Such Buyer further
acknowledges the additional risks associated with the transactions contemplated by this Agreement as set forth on the Schedule
of Additional Risk Factors attached hereto. Neither such inquiries nor any other diligence investigation conducted by such Buyer
or any of its advisors or representatives shall modify, amend or effect such Buyer’s right to rely upon the Company’s
representations and warranties and covenants contained herein or in the Transaction Documents. As used in this Agreement, “SEC
Documents” means all reports, schedules, forms, statements and other documents, including the exhibits thereto and documents
incorporated by reference therein, filed by the Company pursuant to the 1933 Act and the 1934 Act, including pursuant to Section
13(a) or 15(d) thereof, since August 23, 2013.

 

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(k)          No
Government Recommendation or Approval. Such Buyer understands that no United States federal or state agency, or similar agency
of any other country, has reviewed, approved, passed upon, or made any recommendation or endorsement of the Company or the purchase
of the Securities or the fairness or suitability of the investment in the Securities nor have such authorities passed upon or endorsed
the merits of the offering of the Securities.

 

(l)          No
Intent to Effect a Change of Control. Such Buyer has no present intent to effect a “change of control” of the Company
as such term is understood under the rules promulgated pursuant to Section 13(d) of the 1934 Act.

 

(m)          No
Conflicts. The execution, delivery and performance by such Buyer of this Agreement and the consummation by such Buyer of the
transactions contemplated hereby will not (i) result in a violation of the organizational documents of such Buyer or (ii) conflict
with, or constitute a default (or an event which with notice or lapse of time or both would become a default) under, or give to
others any rights of termination, amendment, acceleration or cancellation of, any agreement, indenture or instrument to which such
Buyer is a party, or (iii) result in a violation of any law, rule, regulation, order, judgment or decree (including federal and
state securities laws) applicable to such Buyer, except in the case of clauses (ii) and (iii) above, for such that are not material
and do not otherwise affect the ability of such Buyer to consummate the transactions contemplated hereby.

 

(n)          Section
13(d)(3) of 1934 Act. The several Buyers shall not constitute a “group” within the meaning of Section 13(d)(3)
of the 1934 Act and the rules and regulations promulgated thereunder.

 

(o)          Former
Shell Company. Such Buyer acknowledges and understands that the Company was formerly a “shell company” as defined
in Rule 12b-2 under the 1934 Act.

 

		3.	REPRESENTATIONS AND WARRANTIES
OF THE COMPANY.

 

Except as set forth
under the corresponding section of the disclosure schedules delivered to each Buyer concurrently herewith (the “Disclosure
Schedules”), which Disclosure Schedules shall be deemed a part hereof, and except as otherwise described in the SEC Documents
(excluding Sections 3(q) and 3(ii), where such exceptions shall only apply when expressly stated therein) or in the Disclosure
Schedules, the Company represents and warrants to each of the Buyers that:

 

(a)          Organization
and Qualification. The Company and each of its Subsidiaries are entities duly organized and validly existing and in good standing
under the laws of the jurisdiction in which they are formed, and have the requisite power and authorization to own their properties
and to carry on their business as now being conducted and as presently proposed to be conducted. Each of the Company and each of
its Subsidiaries is duly qualified as a foreign entity to do business and is in good standing in every jurisdiction in which its
ownership of property or the nature of the business conducted by it makes such qualification necessary, except to the extent that
the failure to be so qualified or be in good standing would not, individually or in the aggregate, have a Material Adverse Effect.
As used in this Agreement, “Material Adverse Effect” means any material adverse effect on (i) the business,
properties, assets, liabilities, operations (including results thereof), condition (financial or otherwise) or prospects of the
Company or any Subsidiary, individually or taken as a whole, (ii) the transactions contemplated hereby or in any of the other Transaction
Documents or (iii) the authority or ability of the Company to perform any of its obligations under any of the Transaction Documents.
“Subsidiaries” means any Person in which the Company, directly or indirectly, (I) owns a majority of the outstanding
capital stock or equity or similar interest of such Person or (II) controls or operates all or any part of the business, operations
or administration of such Person, and each of the foregoing is individually referred to herein as a “Subsidiary.”

 

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(b)          Authorization;
Enforcement; Validity. The Company has the requisite power and authority to enter into and perform its obligations under this
Agreement and the other Transaction Documents and to issue the Securities in accordance with the terms hereof and thereof. The
execution and delivery of this Agreement and the other Transaction Documents by the Company and the consummation by the Company
of the transactions contemplated hereby and thereby (including, without limitation, the issuance of the Common Shares, the issuance
of the Warrants and the reservation for issuance and issuance of the Warrant Shares issuable upon exercise of the Warrants) have
been duly authorized by the Company’s board of directors and (other than the filing with United States Securities and Exchange
Commission (the “SEC”) of one or more Registration Statements (as defined the Registration Rights Agreement),
a Current Report on Form 8-K and a Form D and any other filings as may be required by any state securities agencies) no further
filing, consent or authorization is required by the Company, its board of directors or its stockholders or other governing body
in connection therewith. This Agreement has been, and the other Transaction Documents will be prior to the Initial Closing, duly
executed and delivered by the Company, and each constitutes the legal, valid and binding obligations of the Company, enforceable
against the Company in accordance with its respective terms, except as such enforceability may be limited by general principles
of equity or applicable bankruptcy, insolvency, reorganization, moratorium, liquidation or similar laws relating to, or affecting
generally, the enforcement of applicable creditors’ rights and remedies and except as rights to indemnification and to contribution
may be limited by federal or state securities law. “Transaction Documents” means, collectively, this Agreement,
the Registration Rights Agreement the Warrants, the Irrevocable Transfer Agent Instructions and each of the other agreements and
instruments entered into or delivered by any of the parties hereto in connection with the transactions contemplated hereby and
thereby, as may be amended from time to time.

 

(c)          Issuance
of Securities. The issuance of the Common Shares and the Warrants are duly authorized and, upon issuance in accordance with
the terms of the Transaction Documents, will be validly issued, fully paid and non-assessable and free from all preemptive or similar
rights, taxes, liens, charges and other encumbrances with respect to the issue thereof. As of the Initial Closing, the Company
shall have reserved from its duly authorized capital stock the maximum number of shares of Common Stock issuable upon exercise
of the Warrants (without taking into account any limitations on the exercise of the Warrants set forth therein). The issuance of
the Warrant Shares is duly authorized, and upon exercise in accordance with the Warrants, the Warrant Shares, when issued, will
be validly issued, fully paid and non-assessable and free from all preemptive or similar rights, taxes, liens, charges and other
encumbrances with respect to the issue thereof, with the holders being entitled to all rights accorded to a holder of Common Stock.
Subject to the accuracy of the representations and warranties of the Buyers in this Agreement, the offer and issuance by the Company
of the Securities is exempt from registration under the 1933 Act. The Company (i) has not distributed any offering material in
connection with the offering and sale of any of the Securities and (ii) until no Buyer holds any of the Securities, shall not distribute
any offering material in connection with the offering and sale of any of the Securities to, or by, any of the Buyers, in each case,
other than the Registration Statement(s) (or the prospectuses contained therein).

 

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(d)          No
Conflicts. Except as set forth on Section 3(d) of the Disclosure Schedule, the execution, delivery and performance of
the Transaction Documents by the Company and the consummation by the Company of the transactions contemplated hereby and thereby
(including, without limitation, the issuance of the Common Shares, the Warrants and Warrant Shares and the reservation for issuance
of the Warrant Shares) will not (i) result in a violation of the Certificate of Incorporation (as defined below) (including, without
limitation, any certificates of designation contained therein) or other organizational documents of the Company or any of its Subsidiaries,
any capital stock of the Company (including the Series B Convertible Preferred Stock), or Bylaws (as defined below), (ii) result
in the adjustment of the exercise, conversion or exchange price and/or ratio in respect of any securities of the Company or any
of its Subsidiaries, (iii) result in any such securities exercisable, convertible or exchangeable for a greater number of underlying
securities, or require the approval or the receipt of waivers from any holders of any instrument or class of securities or counterparties
to any agreement or understanding to which the Company or any Subsidiary is a party, (iv) conflict with, or constitute a default
(or an event which with notice or lapse of time or both would become a default) under, or give to others any rights of termination,
amendment, acceleration or cancellation of, any agreement, indenture or instrument to which the Company or any of its Subsidiaries
is a party, or (v) result in a violation of any law, rule, regulation, order, judgment or decree (including, without limitation,
federal and state and foreign securities laws and regulations and the rules and regulations of the Principal Market (the “Principal
Market” being the Eligible Market that is the principal securities exchange market for the
Common Stock)) applicable to the Company or any of its Subsidiaries or by which any property or asset of the Company or
any of its Subsidiaries is bound or affected.

 

(e)          Consents.
Except as set forth on Section 3(e) of the Disclosure Schedule, the Company is not required to obtain any consent from,
authorization or order of, or make any filing which has not already been obtained or made (including, without limitation as to
the quotation on the Principal Market of the Common Shares and the Warrant Shares upon issuance) or registration with (other than
the filing with the SEC of the Registration Statement, a Form D, a Current Report on Form 8-K, and any other filings as may be
required by any state securities agencies), any court, governmental agency or any regulatory or self-regulatory agency or any other
Person in order for it to execute, deliver or perform any of its obligations under or contemplated by the Transaction Documents,
in each case, in accordance with the terms hereof or thereof. All consents, authorizations, orders, filings and registrations which
the Company is required to obtain at or prior to the Initial Closing will have been obtained or effected on or prior to the Initial
Closing Date, and neither the Company nor any of its Subsidiaries are aware of any facts or circumstances which might prevent the
Company from obtaining or effecting any of the registration, application or filings contemplated by the Transaction Documents.
The Company is Knowingly not in violation of the requirements of the Principal Market or foreign, federal, state or local securities
laws, and has no Knowledge of any facts or circumstances which could reasonably lead to such violation or suspension of the Common
Stock in the foreseeable future. No statute, rule, regulation, executive order, decree, ruling or injunction has been enacted,
entered, promulgated or endorsed by any court or governmental authority of competent jurisdiction that prohibits the consummation
of any of any of the transactions contemplated by the Transaction Documents, and no actions, suits or proceedings are pending or
threatened by any Person that seeks to enjoin, prohibit or otherwise adversely affect any of the transactions contemplated by the
Transaction Documents.

 

(f)          Acknowledgment
Regarding Buyer’s Purchase of Securities. Except as set forth on Section 3(f) of the Disclosure Schedule, the
Company acknowledges and agrees that each Buyer is acting solely in the capacity of an arm’s length purchaser with respect
to the Transaction Documents and the transactions contemplated hereby and thereby and that no Buyer is (i) an officer or director
of the Company or any of its Subsidiaries or (ii) an “affiliate” (as defined in Rule 144 promulgated under the 1933
Act (or a successor rule thereto) (collectively, “Rule 144”)) of the Company (an “Affiliate”)
or any of its Subsidiaries. Except as set forth on Section 3(f) of the Disclosure Schedule, the Company further acknowledges
that no Buyer is acting as a financial advisor or fiduciary of the Company or any of its Subsidiaries (or in any similar capacity)
with respect to the Transaction Documents and the transactions contemplated hereby and thereby, and any advice given by a Buyer
or any of its representatives or agents in connection with the Transaction Documents and the transactions contemplated hereby and
thereby is merely incidental to such Buyer’s purchase of the Securities. The Company further represents to each Buyer that
the Company’s decision to enter into the Transaction Documents has been based solely on the independent evaluation by the
Company and its representatives. The Company is no longer an issuer identified in Rule 144(i)(1)(i) and at least one year has passed
since the Company filed the “Form 10 information” with the SEC to be filed pursuant to Rule 144(i)(2) when the Company
last ceased being an issuer identified in, or subject to, Rule 144(i).

 

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(g)          Placement
Agent’s Fees. The Company shall be responsible for the payment of any placement agent’s fees, financial advisory
fees, or brokers’ commissions (other than for Persons engaged by any Buyer or its investment advisor) relating to or arising
out of the transactions contemplated hereby, as outlined on Section 3(g) of the Disclosure Schedule.

 

(h)          No
Integrated Offering. Neither the Company, its Subsidiaries or any of their Affiliates, nor any Person acting on their behalf
has, directly or indirectly, made any offers or sales of any security or solicited any offers to buy any security, under circumstances
that would cause this offering of the Securities to require approval of stockholders of the Company under any applicable stockholder
approval provisions, including, without limitation, under the rules and regulations of any exchange or automated quotation system
on which any of the securities of the Company are listed or designated for quotation. No registration of the offer, sale or transfer
of any of the Securities is required, except for registration contemplated hereby pursuant to the Registration Rights Agreement.

 

(i)          Application
of Takeover Protections. The Company and its board of directors have taken all necessary action, if any, in order to render
inapplicable any control share acquisition, interested stockholder, business combination, poison pill (including, without limitation,
any distribution under a rights agreement) or other similar anti-takeover provision under the Certificate of Incorporation, Bylaws
or other organizational documents or the laws of the jurisdiction of its incorporation or otherwise that can be waived by approval
of the board of directors and which is or could become applicable to any Buyer as a result of the transactions contemplated by
this Agreement, including, without limitation, the Company’s issuance of the Securities and any Buyer’s ownership of
the Securities. The Company and its board of directors have taken all necessary action, if any, in order to render inapplicable
any stockholder rights plan or similar arrangement relating to accumulations of beneficial ownership of shares of Common Stock
or a change in control of the Company or any of its Subsidiaries.

 

(j)           SEC
Reports; Financial Statements. During the two years prior to the date hereof, the Company has timely filed all reports, schedules,
forms, statements and other documents required to be filed by it with the SEC pursuant to the reporting requirements of the 1934
Act (all of the foregoing filed prior to the date hereof and all exhibits included therein and financial statements, notes and
schedules thereto and documents incorporated by reference therein being hereinafter referred to as the “SEC Reports”).
As of their respective dates, the SEC Reports complied in all material respects with the requirements of the 1934 Act and the rules
and regulations of the SEC promulgated thereunder applicable to the SEC Reports, and none of the SEC Reports, at the time they
were filed with the SEC, contained any untrue statement of a material fact or omitted to state a material fact required to be stated
therein or necessary in order to make the statements therein, in the light of the circumstances under which they were made, not
misleading. As of their respective dates, the financial statements of the Company included in the SEC Reports complied in all material
respects with applicable accounting requirements and the published rules and regulations of the SEC with respect thereto as in
effect as of the time of filing. Such financial statements have been prepared in accordance with generally accepted accounting
principles, consistently applied, during the periods involved (except (i) as may be otherwise indicated in such financial statements
or the notes thereto, or (ii) in the case of unaudited interim statements, to the extent they may exclude footnotes or may be condensed
or summary statements) and fairly present in all material respects the financial position of the Company as of the dates thereof
and the results of its operations and cash flows for the periods then ended (subject, in the case of unaudited statements, to normal
year-end audit adjustments which will not be material, either individually or in the aggregate). No other information provided
by or on behalf of the Company to any Buyer which is not included in the SEC Reports contains any untrue statement of a material
fact or omits to state any material fact necessary, in order to make the statements therein not misleading, in light of the circumstances
under which they are or were made.

 

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(k)          Absence
of Certain Changes. Since the date of the Company’s most recent audited financial statements contained in a Form 10-K,
except as disclosed in Section 3(k) of the Disclosure Schedule and the SEC Documents filed subsequent thereto, there has
been no material adverse change and no material adverse development in the business, assets, liabilities, properties, operations
or financial condition of the Company. Since the date of the Company’s most recent audited financial statements contained
in a Form 10-K, except as disclosed in Section 3(k) of the Disclosure Schedule and the SEC Documents filed subsequent thereto,
neither the Company nor any of its Subsidiaries has (i) declared or paid any dividends, (ii) sold any assets, individually or in
the aggregate, outside of the ordinary course of business or (iii) made any material capital expenditures, individually or in the
aggregate. Neither the Company nor any of its Subsidiaries has taken any steps to seek protection pursuant to any law or statute
relating to bankruptcy, insolvency, reorganization, receivership, liquidation or winding up, nor does the Company or any Subsidiary
have any Knowledge or reason to believe that any of their respective creditors intend to initiate involuntary bankruptcy proceedings
or any actual Knowledge of any fact which would reasonably lead a creditor to do so. Except as provided in the SEC Reports, the
Company and its Subsidiaries, individually and on a consolidated basis, are not as of the date hereof, and after giving effect
to the transactions contemplated hereby to occur at the Initial Closing will not be, Insolvent (as defined below). For purposes
of this Section, “Insolvent” means, (I) with respect to the Company and its Subsidiaries, on a consolidated
basis, (i) the present fair saleable value of the Company’s and its Subsidiaries’ assets is less than the amount required
to pay the Company’s and its Subsidiaries’ total Indebtedness (as defined below), (ii) the Company and its Subsidiaries
are unable to pay their debts and liabilities, subordinated, contingent or otherwise, as such debts and liabilities become absolute
and matured or (iii) the Company and its Subsidiaries intend to incur or believe that they will incur debts that would be beyond
their ability to pay as such debts mature; and (II) with respect to the Company and each Subsidiary, individually, (i) the present
fair saleable value of the Company’s or such Subsidiary’s (as the case may be) assets is less than the amount required
to pay its respective total Indebtedness, (ii) the Company or such Subsidiary (as the case may be) is unable to pay its respective
debts and liabilities, subordinated, contingent or otherwise, as such debts and liabilities become absolute and matured or (iii)
the Company or such Subsidiary (as the case may be) intends to incur or believes that it will incur debts that would be beyond
its respective ability to pay as such debts mature. Neither the Company nor any of its Subsidiaries has engaged in any business
or in any transaction, and is not about to engage in any business or in any transaction, for which the Company’s or such
Subsidiary’s remaining assets constitute unreasonably small capital.

 

(l)          No
Undisclosed Events, Liabilities, Developments or Circumstances. Since the date of the Company’s most recent audited financial
statements contained in a Form 10-K, except as disclosed in Section 3(l) of the Disclosure Schedule and the SEC Documents
filed subsequent thereto, no event, liability, development or circumstance has occurred or exists, or is reasonably expected to
exist or occur with respect to the Company, any of its Subsidiaries or their respective business, properties, liabilities, operations
or financial condition that (i) is required to be disclosed by the Company under applicable securities laws on a registration statement
filed with the SEC relating to an issuance and sale by the Company of its Common Stock and which has not been publicly announced,
or (ii) could reasonably be expected to have a Material Adverse Effect.

 

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(m)          Conduct
of Business; Regulatory Permits. Neither the Company nor any of its Subsidiaries is in violation of any term of or in default
under its Certificate of Incorporation, any certificate of designation, preferences or rights of any other outstanding series of
preferred stock of the Company or any of its Subsidiaries or Bylaws or their organizational charter, certificate of formation or
certificate of incorporation or bylaws, respectively. Neither the Company nor any of its Subsidiaries is in violation of any judgment,
decree or order or any statute, ordinance, rule or regulation applicable to the Company or any of its Subsidiaries, and neither
the Company nor any of its Subsidiaries will conduct its business in violation of any of the foregoing, except in all cases for
possible violations which would not, individually or in the aggregate, have a Material Adverse Effect. Without limiting the generality
of the foregoing, to the Company’s Knowledge, the Company is not in violation of any of the rules, regulations or requirements
of the Principal Market and has no Knowledge of any facts or circumstances that could reasonably lead to suspension of the Common
Stock by the Principal Market in the foreseeable future and the Company is in compliance with all requirements in order to maintain
quotation on the Principal Market. Since October 2, 2013, (i) the Common Stock has been designated for quotation on the Principal
Market, (ii) trading in the Common Stock has not been suspended by the SEC or the Principal Market and (iii) the Company has received
no communication, written or oral, from the SEC or the Principal Market regarding or relating to the suspension of the Common Stock
from the Principal Market. The Company and each of its Subsidiaries possess all certificates, authorizations and permits issued
by the appropriate regulatory authorities necessary to conduct their respective businesses, except where the failure to possess
such certificates, authorizations or permits would not have, individually or in the aggregate, a Material Adverse Effect, and neither
the Company nor any such Subsidiary has received any notice of proceedings relating to the revocation or modification of any such
certificate, authorization or permit.

 

(n)          Foreign
Corrupt Practices; Certain Other Unlawful Matters. Neither the Company nor any of its Subsidiaries, nor to the Knowledge of
the Company, any director, officer, agent, employee or other Person acting on behalf of the Company or any of its Subsidiaries
has, in the course of its actions for, or on behalf of, the Company or any of its Subsidiaries (i) used any corporate funds for
any unlawful contribution, gift, entertainment or other unlawful expenses relating to political activity; (ii) made any direct
or indirect unlawful payment to any foreign or domestic government official or employee from corporate funds; (iii) violated or
is in violation of any provision of the U.S. Foreign Corrupt Practices Act of 1977, as amended (or rules or regulations or interpretations
thereunder); or (iv) made any unlawful bribe, rebate, payoff, influence payment, kickback or other unlawful payment to any foreign
or domestic government official or employee or otherwise. The Company and its Subsidiaries are in compliance with, and have not
previously violated, the USA Patriot Act of 2001 and all other applicable U.S. and non-U.S. anti-money laundering laws and regulations,
including, without limitation, the laws, regulations and Executive Orders and sanctions programs administered by the U.S. Office
of Foreign Assets Control, including, without limitation, (i) Executive Order 13224 of September 23, 2001 entitled, “Blocking
Property and Prohibiting Transactions With Persons Who Commit, Threaten to Commit, or Support Terrorism” (66 Fed. Reg. 49079
(2001)); and (ii) any regulations contained in 31 CFR, Subtitle B, Chapter V.

 

(o)          Sarbanes-Oxley
Act. The Company and each Subsidiary is in compliance with all applicable requirements of the Sarbanes-Oxley Act of 2002, and
all applicable rules and regulations promulgated by the SEC thereunder.

 

(p)          Transactions
With Affiliates. Except as disclosed in Section 3(p) of the Disclosure Schedule and the SEC Documents, none of the officers,
directors or employees or Affiliates of the Company or any of its Subsidiaries is presently a party to any transaction with the
Company or any of its Subsidiaries (other than for ordinary course services as employees, officers or directors), including any
contract, agreement or other arrangement providing for the furnishing of services to or by, providing for rental of real or personal
property to or from, or otherwise requiring payments to or from any such officer, director or employee or, to the Knowledge of
the Company or any of its Subsidiaries, any corporation, partnership, trust or other Person in which any such officer, director
or employee or Affiliate has a substantial interest or is an employee, officer, director, trustee or partner.

 

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		(q)	Equity Capitalization. The authorized capital stock
of the Company consists of

 

(i)            as
of November 17, 2016 and excluding the Securities, 400,000,000 shares of Common Stock, of which 49,847,167 shares are issued and
outstanding,

 

(ii)           as
of November 17, 2016 and excluding the Securities, 50,000,000 shares of preferred stock, of which 24,325,000 shares have been designated
as Series A Convertible Preferred Stock, of which no shares are issued and outstanding shares and 333,333 shares have been designated
as Series B Convertible Preferred Stock, of which 255,927.4 shares are issued and outstanding and shall be converted into an aggregate
of 26,425,973 shares of Common Stock following the entry into of this Agreement and immediately prior to the Initial Closing, and

 

(iii)          as
of November 17, 2016 and excluding the Securities, other securities convertible or exercisable into a total of 93,292,9719 shares
of Common Stock, consisting of 83,360,437 shares of Common Stock underlying warrants and 9,932,534 shares of Common Stock underlying
options.

 

On or prior to the date
hereof, the Company shall have filed an Amendment to its Certificate of Designations for the Series B Convertible Preferred Stock
relating to the forced conversion of the Series B Convertible Preferred Stock following the entry into of this Agreement and immediately
prior to the Initial Closing. The Company intends to effect a reverse stock split of its Common Stock (the “Reverse Stock
Split”) within thirty (30) days following the Final Closing.

 

No shares of Common Stock
are held in treasury. All of such outstanding shares are duly authorized and have been, or upon issuance will be, validly issued
and are fully paid and non-assessable.

 

As of November 17, 2016,
excluding the Securities, 15,111,454 shares of the Company’s issued and outstanding Common Stock on the date hereof are owned
by Persons who are “Affiliates” of the Company or any of its Subsidiaries. For purposes of this paragraph, “Affiliate
shall be as defined in Rule 405 of the 1933 Act and calculated based on the assumption that officers, directors and holders of
at least 10% of the Company’s issued and outstanding Common Stock (and only such persons) are “Affiliates” without
conceding that any such Persons are “Affiliates” for purposes of federal securities laws.

 

Except as set forth in
Section 3(q) of the Disclosure Schedule, none of the Company’s or any Subsidiary’s capital stock is subject
to preemptive rights or any other similar rights or any liens or encumbrances suffered or permitted by the Company or any Subsidiary.
Except as set out in this Agreement, as of November 17, 2016, there are no outstanding options, warrants, scrip, rights to subscribe
to, calls or commitments of any character whatsoever relating to, or securities or rights convertible into, or exercisable or exchangeable
for, any capital stock of the Company or any of its Subsidiaries, or contracts, commitments, understandings or arrangements by
which the Company or any of its Subsidiaries is or may become bound to issue additional capital stock of the Company or any of
its Subsidiaries or options, warrants, scrip, rights to subscribe to, calls or commitments of any character whatsoever relating
to, or securities or rights convertible into, or exercisable or exchangeable for, any capital stock of the Company or any of its
Subsidiaries. Except as set forth in Section 3(q) of the Disclosure Schedule and the SEC Reports, (A) there are no outstanding
debt securities, notes, credit agreements, credit facilities or other agreements, documents or instruments evidencing Indebtedness
of the Company or any of its Subsidiaries or by which the Company or any of its Subsidiaries is or may become bound; (B) there
are no financing statements securing obligations in any amounts filed in connection with the Company or any of its Subsidiaries;
(C) there are no agreements or arrangements under which the Company or any of its Subsidiaries is obligated to register the sale
of any of their securities under the 1933 Act (except pursuant to the Transaction Documents); (D) there are no outstanding securities
or instruments of the Company or any of its Subsidiaries which contain any redemption or similar provisions, and there are no contracts,
commitments, understandings or arrangements by which the Company or any of its Subsidiaries is or may become bound to redeem a
security of the Company or any of its Subsidiaries; (E) there are no securities or instruments containing anti-dilution or similar
provisions that will be triggered by the issuance of the Securities; (F) neither the Company nor any Subsidiary has any stock appreciation
rights or “phantom stock” plans or agreements or any similar plan or agreement; and (G) neither the Company nor any
of its Subsidiaries has any liabilities or obligations required to be disclosed in the SEC Reports which are not so disclosed in
the SEC Documents, other than those incurred in the ordinary course of the Company’s or its Subsidiaries’ respective
businesses and which, individually or in the aggregate, do not or would not have a Material Adverse Effect. The SEC Documents
contain true, correct and complete copies of the Company’s Certificate of Incorporation, as amended and as in effect on the
date hereof (the “Certificate of Incorporation”), and the Company’s bylaws, as amended and as in effect
on the date hereof (the “Bylaws”), and the terms of all securities convertible into, or exercisable or exchangeable
for, shares of Common Stock and the material rights of the holders thereof in respect thereto. For the sake of clarity, the number
of shares provided in this Section 3(q) with respect to November 17, 2016 are provided as of the close of business on such date,
and such numbers are prior to giving effect to the conversion as contemplated above.

 

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(r)          Indebtedness
and Other Contracts. Except as provided in Section 3(r) of the Disclosure Schedule and the SEC Reports, neither the
Company nor any of its Subsidiaries (i) has any outstanding Indebtedness, (ii) is a party to any contract, agreement or instrument,
the violation of which, or default under which, by the other party or parties to such contract, agreement or instrument could reasonably
be expected to result in a Material Adverse Effect, (iii) is in violation of any term of, or in default under, any contract, agreement
or instrument relating to any Indebtedness, except where such violations and defaults would not result, individually or in the
aggregate, in a Material Adverse Effect, or (iv) is a party to any contract, agreement or instrument relating to any Indebtedness,
the performance of which, in the judgment of the Company’s officers, has or is expected to have a Material Adverse Effect
since the date of the Company’s most recent audited financial statements contained in a Form 10-K. For purposes of this Agreement:
(x) “Indebtedness” of any Person means, without duplication (A) all indebtedness for borrowed money, (B) all
obligations issued, undertaken or assumed as the deferred purchase price of property or services (including, without limitation,
“capital leases” in accordance with generally accepted accounting principles) (other than trade payables entered into
in the ordinary course of business), (C) all reimbursement or payment obligations with respect to letters of credit, surety bonds
and other similar instruments, (D) all obligations evidenced by notes, bonds, debentures or similar instruments, including obligations
so evidenced incurred in connection with the acquisition of property, assets or businesses, (E) all indebtedness created or arising
under any conditional sale or other title retention agreement, or incurred as financing, in either case with respect to any property
or assets acquired with the proceeds of such indebtedness (even though the rights and remedies of the seller or bank under such
agreement in the event of default are limited to repossession or sale of such property), (F) all monetary obligations under any
leasing or similar arrangement which, in connection with generally accepted accounting principles, consistently applied for the
periods covered thereby, is classified as a capital lease, (G) all indebtedness referred to in clauses (A) through (F) above secured
by (or for which the holder of such Indebtedness has an existing right, contingent or otherwise, to be secured by) any mortgage,
lien, pledge, charge, security interest or other encumbrance upon or in any property or assets (including accounts and contract
rights) owned by any Person, even though the Person which owns such assets or property has not assumed or become liable for the
payment of such indebtedness, and (H) all Contingent Obligations in respect of indebtedness or obligations of others of the kinds
referred to in clauses (A) through (G) above; (y) “Contingent Obligation” means, as to any Person, any direct
or indirect liability, contingent or otherwise, of that Person with respect to any indebtedness, lease, dividend or other obligation
of another Person if the primary purpose or intent of the Person incurring such liability, or the primary effect thereof, is to
provide assurance to the obligee of such liability that such liability will be paid or discharged, or that any agreements relating
thereto will be complied with, or that the holders of such liability will be protected (in whole or in part) against loss with
respect thereto; and (z) “Person” means an individual, a limited liability company, a partnership, a joint venture,
a corporation, a trust, an unincorporated organization, any other entity and a government or any department or agency thereof.

 

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(s)          Absence
of Litigation. There is no action, suit, proceeding, inquiry or investigation before or by any court, public board, government
agency, self-regulatory organization or body pending or, to the Knowledge of the Company, threatened against or affecting the Company
or any of its Subsidiaries, the Common Stock or any of the Company’s or its Subsidiaries’ officers or directors which
is outside of the ordinary course of business or individually or in the aggregate material to the Company or any of its Subsidiaries.
There has not been, and to the Knowledge of the Company, there is not pending or contemplated, any investigation by the SEC involving
the Company, any of its Subsidiaries or any current or former director or officer of the Company or any of its Subsidiaries. The
SEC has not issued any stop order or other order suspending the effectiveness of the Registration Statement.

 

(t)          Insurance.
The Company and each of its Subsidiaries are insured by insurers of recognized financial responsibility against such losses and
risks and in such amounts as management of the Company believes to be prudent and customary in the businesses in which the Company
and its Subsidiaries are engaged. Neither the Company nor any such Subsidiary has been refused any insurance coverage sought or
applied for, and neither the Company nor any such Subsidiary has any reason to believe that it will be unable to renew its existing
insurance coverage as and when such coverage expires or to obtain similar coverage from similar insurers as may be necessary to
continue its business at a cost that would not have a Material Adverse Effect.

 

(u)          Employee
Relations. Neither the Company nor any of its Subsidiaries is a party to any collective bargaining agreement or employs any
member of a union. No executive officer (as defined in Rule 501(f) promulgated under the 1933 Act) or other key employee of the
Company or any of its Subsidiaries has notified the Company or any such Subsidiary that such officer intends to leave the Company
or any such Subsidiary or otherwise terminate such officer’s employment with the Company or any such Subsidiary. No executive
officer or other key employee of the Company or any of its Subsidiaries is, or is now expected by the Company to be, in connection
with employment by the Company, in violation of any material term of any employment contract, confidentiality, disclosure or proprietary
information agreement, non-competition agreement, or any other contract or agreement or any restrictive covenant, and the continued
employment of each such executive officer or other key employee (as the case may be) does not subject the Company or any of its
Subsidiaries to any liability with respect to any of the foregoing matters. The Company and its Subsidiaries are in compliance
with all federal, state, local and foreign laws and regulations respecting labor, employment and employment practices and benefits,
terms and conditions of employment and wages and hours, except where failure to be in compliance would not, either individually
or in the aggregate, reasonably be expected to result in a Material Adverse Effect.

 

(v)         Title.
The Company and its Subsidiaries have good and marketable title in fee simple to all real property, and have good and marketable
title to all personal property, owned by them which is material to the business of the Company and its Subsidiaries, in each case,
free and clear of all liens, encumbrances and defects except such as do not materially affect the value of such property and do
not interfere with the use made and proposed to be made of such property by the Company and any of its Subsidiaries. Any real property
and facilities held under lease by the Company or any of its Subsidiaries are held by them under valid, subsisting and enforceable
leases with such exceptions as are not material and do not interfere with the use made and proposed to be made of such property
and buildings by the Company or any of its Subsidiaries.

 

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(w)          Intellectual
Property Rights. The Company and its Subsidiaries own or possess adequate rights or licenses to use all trademarks, trade names,
service marks, service mark registrations, service names, patents, patent rights, copyrights, original works, inventions, licenses,
approvals, governmental authorizations, trade secrets and other intellectual property rights and all applications and registrations
therefor (“Intellectual Property Rights”) necessary to conduct their respective businesses as now conducted.
The Company has no Knowledge of any infringement by the Company or any of its Subsidiaries of intellectual property rights of others.
Neither the Company nor its Subsidiary has any Knowledge of any claim, action or proceeding being made or brought it or being threatened,
against the Company or any of its Subsidiaries regarding their Intellectual Property Rights. Neither the Company nor its Subsidiary
has any Knowledge of any facts or circumstances which might give rise to any of the foregoing infringements or claims, actions
or proceedings. The Company and each of its Subsidiaries have taken reasonable security measures to protect the secrecy, confidentiality
and value of all of their Intellectual Property Rights.

 

(x)          Environmental
Laws. To the best of the Company’s Knowledge, for all activities which the Company is specifically and directly involved
in, the Company and its Subsidiaries (i) are in compliance with all Environmental Laws (as defined below), (ii) have received all
permits, licenses or other approvals required of them under applicable Environmental Laws to conduct their respective businesses
and (iii) are in compliance with all terms and conditions of any such permit, license or approval where, in each of the foregoing
clauses (i), (ii) and (iii), the failure to so comply could be reasonably expected to have, individually or in the aggregate, a
Material Adverse Effect. The term “Environmental Laws” means all federal, state, local or foreign laws of the
applicable jurisdictions to which the Company is subject relating to pollution or protection of human health or the environment
(including, without limitation, ambient air, surface water, groundwater, land surface or subsurface strata), including, without
limitation, laws relating to emissions, discharges, releases or threatened releases of chemicals, pollutants, contaminants, or
toxic or hazardous substances or wastes (collectively, “Hazardous Materials”) into the environment, or otherwise
relating to the manufacture, processing, distribution, use, treatment, storage, disposal, transport or handling of Hazardous Materials,
as well as all authorizations, codes, decrees, demands or demand letters, injunctions, judgments, licenses, notices or notice letters,
orders, permits, plans or regulations issued, entered, promulgated or approved thereunder.

 

(y)          Subsidiary
Rights. The Company or one of its Subsidiaries has the unrestricted right to vote, and (subject to limitations imposed by applicable
law) to receive dividends and distributions on, all capital securities of its Subsidiaries as owned by the Company or such Subsidiary.

 

(z)          Tax
Status. The Company and each of its Subsidiaries (i) has timely paid all taxes and other governmental assessments and charges
that are material in amount, shown or determined to be due, except those being contested in good faith and (ii) has set aside on
its books provision reasonably adequate for the payment of all taxes for periods subsequent to the periods to which returns, reports
or declarations were due. To the Company’s Knowledge, there are no unpaid taxes in any material amount claimed to be due
by the taxing authority of any jurisdiction, and the officers of the Company and its Subsidiaries know of no basis for any such
claim. The Company is not operated in such a manner as to qualify as a passive foreign investment company, as defined in Section
1297 of the U.S. Internal Revenue Code of 1986, as amended.

 

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(aa)         Internal
Accounting and Disclosure Controls. Except as otherwise provided in the SEC Reports, the Company and each of its Subsidiaries
maintains internal control over financial reporting (as such term is defined in Rule 13a-15(f) under the 1934 Act) that is effective
to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for
external purposes in accordance with generally accepted accounting principles, including that (i) transactions are executed in
accordance with management’s general or specific authorizations, (ii) transactions are recorded as necessary to permit preparation
of financial statements in conformity with generally accepted accounting principles and to maintain asset and liability accountability,
(iii) access to assets or incurrence of liabilities is permitted only in accordance with management’s general or specific
authorization and (iv) the recorded accountability for assets and liabilities is compared with the existing assets and liabilities
at reasonable intervals and appropriate action is taken with respect to any difference. Except as otherwise provided in the SEC
Reports, the Company maintains disclosure controls and procedures (as such term is defined in Rule 13a-15(e) under the 1934 Act)
that are effective in ensuring that information required to be disclosed by the Company in the reports that it files or submits
under the 1934 Act is recorded, processed, summarized and reported, within the time periods specified in the rules and forms of
the SEC, including, without limitation, controls and procedures designed to ensure that information required to be disclosed by
the Company in the reports that it files or submits under the 1934 Act is accumulated and communicated to the Company’s management,
including its principal executive officer or officers and its principal financial officer or officers, as appropriate, to allow
timely decisions regarding required disclosure. Since the date of the Company’s most recent audited financial statements
contained in a Form 10-K, neither the Company nor any of its Subsidiaries has received any notice or correspondence from any accountant
or other Person relating to any potential material weakness or significant deficiency in any part of the internal controls over
financial reporting of the Company or any of its Subsidiaries.

 

(bb)        Off
Balance Sheet Arrangements. There is no transaction, arrangement, or other relationship between the Company or any of its Subsidiaries
and an unconsolidated or other off balance sheet entity that is required to be disclosed by the Company in its 1934 Act filings
and is not so disclosed or that otherwise could be reasonably likely to have a Material Adverse Effect.

 

(cc)         Investment
Company Status. The Company is not, and upon consummation of the sale of the Securities will not be, an “investment company,”
an Affiliate of an “investment company,” a company controlled by an “investment company” or an “affiliated
person” of, or “promoter” or “principal underwriter” for, an “investment company” as
such terms are defined in the Investment Company Act of 1940, as amended.

 

(dd)        Acknowledgement
Regarding Buyers’ Trading Activity. Except for the certain Buyers set forth on Section 3(dd) of the Disclosure Schedule
and Section 4(f) of the Disclosure Schedule which have entered into a confidential disclosure agreement with the Company that prohibits
trading in the Company’s securities until certain material, non-public information received is publicly announced, it is
understood and acknowledged by the Company that (i) following the public disclosure of the transactions contemplated by the Transaction
Documents, in accordance with the terms thereof, none of the Buyers have been asked by the Company or any of its Subsidiaries to
agree, nor has any Buyer agreed with the Company or any of its Subsidiaries, to desist from effecting any transactions in or with
respect to (including, without limitation, purchasing or selling, long and/or short) any securities of the Company, or “derivative”
securities based on securities issued by the Company or to hold the Securities for any specified term; (ii) any Buyer, and counterparties
in “derivative” transactions to which any such Buyer is a party, directly or indirectly, presently may have a “short”
position in the Common Stock which was established prior to such Buyer’s Knowledge of the transactions contemplated by the
Transaction Documents; and (iii) each Buyer shall not be deemed to have any affiliation with or control over any arm’s length
counterparty in any “derivative” transaction. The Company further understands and acknowledges that following the public
disclosure of the transactions contemplated by the Transaction Documents pursuant to the Press Release (as defined below), one
or more Buyers may engage in hedging and/or trading activities at various times during the period that the Securities are outstanding,
including, without limitation, during the periods that the value and/or number of the Warrant Shares deliverable with respect to
the Securities are being determined and (b) such hedging and/or trading activities, if any, can reduce the value of the existing
stockholders’ equity interest in the Company both at and after the time the hedging and/or trading activities are being conducted.
The Company acknowledges that such aforementioned hedging and/or trading activities do not constitute a breach of this Agreement
or any other Transaction Document or any of the documents executed in connection herewith or therewith.

 

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(ee)        Manipulation
of Price. Neither the Company nor any of its Subsidiaries has, and no Person acting on their behalf has, directly or indirectly,
(i) taken any action designed to cause or to result in the stabilization or manipulation of the price of any security of the Company
or any of its Subsidiaries to facilitate the sale or resale of any of the Securities, (ii) sold, bid for, purchased, or paid any
compensation for soliciting purchases of, any of the Securities, or (iii) paid or agreed to pay to any Person any compensation
for soliciting another to purchase any other securities of the Company or any of its Subsidiaries.

 

(ff)         U.S.
Real Property Holding Corporation. Neither the Company nor any of its Subsidiaries is, or has ever been, and so long as any
of the Securities are held by any of the Buyers, shall become, a U.S. real property holding corporation within the meaning of Section
897 of the Internal Revenue Code of 1986, as amended, and the Company and each Subsidiary shall so certify upon any Buyer’s
request.

 

(gg)         Transfer
Taxes. On each Closing Date, all stock transfer or other taxes (other than income or similar taxes) which are required to be
paid in connection with the issuance and sale of the Securities to be sold to each Buyer hereunder will be, or will have been,
fully paid or provided for by the Company, and all laws imposing such taxes will be or will have been complied with.

 

(hh)         Bank
Holding Company Act. Neither the Company nor any of its Subsidiaries is subject to the Bank Holding Company Act of 1956, as
amended (the “BHCA”) or to regulation by the Board of Governors of the Federal Reserve System (the “Federal
Reserve”). Neither the Company nor, to its Knowledge, any of its Subsidiaries or Affiliates owns or controls, directly
or indirectly, five percent (5%) or more of the outstanding shares of any class of voting securities or twenty-five percent (25%)
or more of the total equity of a bank or any equity that is subject to the BHCA or to regulation by the Federal Reserve. Neither
the Company nor, to its Knowledge, any of its Subsidiaries or Affiliates exercises a controlling influence over the management
or policies of a bank or any entity that is subject to the BHCA or to regulation by the Federal Reserve.

 

(ii)         Registration
Rights. No holder of securities of the Company has rights to the registration of any securities of the Company because of the
issuance of the Securities hereunder that could expose the Company to material liability or any Buyer to any liability or that
could impair the Company’s ability to consummate the issuance and sale of the Securities in the manner, and at the times,
contemplated hereby, which rights have not been waived by the holder thereof as of the date hereof.

 

(jj)         Public
Utility Holding Act. Neither the Company nor any of its Subsidiaries is a “holding company,” or an “Affiliate”
of a “holding company,” as such terms are defined in the Public Utility Holding Act of 2005.

 

(kk)         Federal
Power Act. Neither the Company nor any of its Subsidiaries is subject to regulation as a “public utility” under
the Federal Power Act, as amended.

 

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(ll)         Disclosure.
Except for the certain Buyers set forth on Section 4(f) of the Disclosure Schedule which have entered into a confidential disclosure
agreement with the Company that prohibits trading in the Company’s securities until certain material, non-public information
received is publicly announced, the Company confirms that neither it nor any other Person acting on its behalf has provided any
of the Buyers or their agents or counsel with any information that constitutes or could reasonably be expected to constitute material,
non-public information concerning the Company or any of its Subsidiaries, other than with respect to the transactions contemplated
by this Agreement and the other Transaction Documents and other information contained in the 8-K Filing. The Company understands
and confirms that each of the Buyers will rely on the foregoing representations in effecting transactions in securities of the
Company. All written disclosure provided to the Buyers regarding the Company and its Subsidiaries, their businesses and the transactions
contemplated hereby, including the schedules to this Agreement, furnished by or on behalf of the Company or any of its Subsidiaries
is true and correct in all material respects and does not contain any untrue statement of a material fact or omit to state any
material fact necessary in order to make the statements made therein, in the light of the circumstances under which they were made,
not misleading. Each press release issued by the Company or any of its Subsidiaries during the twelve (12) months preceding the
date of this Agreement did not at the time of release contain any untrue statement of a material fact or omit to state a material
fact required to be stated therein or necessary in order to make the statements therein, in the light of the circumstances under
which they are made, not misleading. No event or circumstance has occurred or information exists with respect to the Company or
any of its Subsidiaries or its or their business, properties, liabilities, prospects, operations (including results thereof) or
conditions (financial or otherwise), which, under applicable law, rule or regulation, requires public disclosure at or before the
date hereof or announcement by the Company but which has not been so publicly disclosed. The Company acknowledges and agrees that
no Buyer makes or has made any representations or warranties with respect to the transactions contemplated hereby other than those
specifically set forth in Section 2.

 

(mm)         Consent
of Holders of Series B Convertible Preferred Stock. Pursuant to the Certificate of Designations, Preferences and Rights of
Series B Convertible Preferred Stock including Section 6 thereof, the Company has obtained the written consent of the holders of
a majority of the Series B Convertible Preferred Stock, Iroquois Master Fund Ltd. and Hudson Bay Master Fund LTD (or their respective
affiliates) approving (i) the mandatory conversion of all shares of the Series B Preferred Stock, with the mandatory conversion
time being immediately prior to the Initial Closing and (ii) the authorization and issuance of the Common Shares and the related
Warrants. The conversion price for the Series B Preferred Stock shall be $0.58 pursuant to the Company’s Certificate of Designations,
Preferences and Rights of Series B Convertible Preferred Stock, as amended.

 

		4.	COVENANTS.

 

(a)          Reporting
Status. Until the date on which no Warrants are outstanding (the “Reporting Period”), the Company shall
file all reports required to be filed with the SEC pursuant to the 1934 Act and the Company shall not terminate its status as an
issuer required to file reports pursuant to the 1934 Act (even if the 1934 Act or the rules and regulations thereunder would no
longer require or otherwise permit such termination).

 

(b)          Financial
Information. If any of the following are filed with the SEC, the Company agrees to send the following to each Buyer during
the Reporting Period, unless the following are filed with the SEC through EDGAR and are available to the public through the EDGAR
system, and unless any, or any portion of, the following has been redacted pursuant to a confidential treatment request or a determination
of confidentiality has been made by the SEC (in which event the following in the form filed with the SEC shall be sent), within
one (1) Business Day after the filing thereof with the SEC, (i) a copy of its Annual Reports on Form 10-K and Quarterly Reports
on Form 10-Q, any interim reports or any consolidated balance sheets, income statements, stockholders’ equity statements
and/or cash flow statements for any period other than annual, any Current Reports on Form 8-K and any registration statements (other
than on Form S-8) or amendments filed pursuant to the 1933 Act, (ii) on the same day as the release thereof, facsimile copies of
all press releases issued by the Company or any of its Subsidiaries and (iii) copies of any notices and other information made
available or given to the stockholders of the Company generally, contemporaneously with the making available or giving thereof
to the stockholders.

 

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(c)          Quotation/Listing.
The Company’s Common Stock is currently designated for quotation on the OTCQB marketplace of the OTC Markets Group, Inc.
The Company shall maintain the Common Stock’s designation for quotation (as the case may be) on the OTCQX marketplace of
the OTC Markets Group, Inc., the OTCQB marketplace of the OTC Markets Group, Inc., The New York Stock Exchange, the NYSE MKT, the
Nasdaq Global Market, the Nasdaq Capital Market or the Nasdaq Global Select Market (each, an “Eligible Market”).
Neither the Company nor any of its Subsidiaries shall take any action which could be reasonably expected to result in the delisting
or suspension of the Common Stock on an Eligible Market (other than in connection with listing on a different Eligible Market).
The Company shall pay all fees and expenses in connection with satisfying its obligations under this Section. The Company intends
to apply for listing of its Common Stock on the NASDAQ Capital Market or NYSE MKT following the Final Closing.

 

(d)          Fees.
The Company shall reimburse Empery Asset Master, LTD (“Empery”) or its designee(s) for all costs and expenses
incurred by it or its affiliates in connection with the transactions contemplated by the Transaction Documents (including, without
limitation, all legal fees and disbursements in connection therewith, structuring, documentation and implementation of the transactions
contemplated by the Transaction Documents and due diligence and regulatory filings in connection therewith) in a non-accountable
amount equal to $20,000, which amount shall be withheld by Empery from its Purchase Price at the Initial Closing or Final Closing,
as applicable. The Company shall be responsible for the payment of any placement agent’s fees, financial advisory fees, broker’s
commissions (other than for Persons engaged by any Buyer), escrow agent fees, transfer agent fees or legal fees incurred by the
Company relating to or arising out of the transactions contemplated hereby (including, without limitation, any fees payable to
the placement agent, Katalyst Securities LLC and GP Nurmenkari Inc. (collectively referred to as the “Placement Agents”)).
The Company shall pay, and hold each Buyer harmless against, any liability, loss or expense (including, without limitation, reasonable
attorneys’ fees and out-of-pocket expenses) arising in connection with any claim relating to any such payment. Except as
otherwise set forth in the Transaction Documents, each party to this Agreement shall bear its own expenses in connection with the
sale of the Securities to the Buyers.

 

(e)          Pledge
of Securities. Notwithstanding anything to the contrary contained in this Agreement, the Company acknowledges and agrees that
the Securities may be pledged by a Buyer in connection with a bona fide margin agreement or other loan or financing arrangement
that is secured by the Securities. The pledge of Securities shall not be deemed to be a transfer, sale or assignment of the Securities
hereunder, and no Buyer effecting a pledge of Securities shall be required to provide the Company with any notice thereof or otherwise
make any delivery to the Company pursuant to this Agreement or any other Transaction Document. The Company hereby agrees to execute
and deliver such documentation as a pledgee of the Securities may reasonably request in connection with a pledge of the Securities
to such pledgee by a Buyer.

 

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(f)          Disclosure
of Transactions and Other Material Information. The Company shall, on or before 9:30 a.m., New York time, on the first Business
Day following the date hereof, issue a press release (the “Press Release”) reasonably acceptable to each of
the Large Investors (as defined below) disclosing all the material terms of the transactions contemplated by the Transaction Documents.
In addition, the Company shall, on or before 9:30 a.m., New York time, on the first Business Day following the date of the Final
Closing, issue a press release reasonably acceptable to each of the Large Investors disclosing the Final Closing. On or before
5:30 p.m., New York time, on or before the fourth Business Day following the date hereof, the Company shall file a Current Report
on Form 8-K describing all the material terms of the transactions contemplated by the Transaction Documents in the form required
by the 1934 Act and attaching all the material Transaction Documents (including, without limitation, this Agreement (and all schedules
to this Agreement) and the form of Warrants) (including all attachments, the “8-K Filing”). From and after the
issuance of the Press Release and the 8-K Filing, the Company shall have disclosed all material, non-public information (if any)
delivered to any of the Buyers (excluding those set out in Schedule 4(f)) by the Company or any of its Subsidiaries, or any of
their respective officers, directors, employees or agents. In addition, effective after the issuance of the Press Release and the
8-K Filing, the Company acknowledges and agrees that any and all confidentiality or similar obligations under any agreement, whether
written or oral, between the Company, any of its Subsidiaries or any of their respective officers, directors, affiliates, employees
or agents, on the one hand, and any of the Buyers or any of their affiliates (other than the Buyers set out in Schedule 4(f)
and any Buyers that have executed a confidentiality agreement with the Company), on the other hand, shall terminate. In addition,
each of the Buyers set out in Schedule 4(f) acknowledges and agrees that any and all confidentiality or similar obligations under
any agreement, whether written or oral, between the Company, any of its Subsidiaries or any of their respective officers, directors,
affiliates, employees or agents, on the one hand, and such Buyer set out in Schedule 4(f) or any of their affiliates, on the other
hand, shall continue before and after the issuance of the Press Release, pursuant to the terms of such agreement. The Company shall
not, and the Company shall not Knowingly allow any of its Subsidiaries and each of its and their respective officers, directors,
employees and agents, to, provide any Buyer with any material, non-public information regarding the Company or any of its Subsidiaries
from and after the date hereof without the express prior written consent of such Buyer. If a Buyer has, or believes it has, received
any such material, nonpublic information regarding the Company or any of its Subsidiaries from the Company, any of its Subsidiaries
or any of their respective officers, directors, affiliates, employees or agents, it may provide the Company with written notice
thereof. The Company shall, within two (2) Trading Days of receipt of such notice, make public disclosure of such material, nonpublic
information. In the event of a breach of any of the foregoing covenants by the Company, any of its Subsidiaries, or any of its
or their respective officers, directors, employees and agents (as determined in the reasonable good faith judgment of such Buyer),
in addition to any other remedy provided herein or in the Transaction Documents, such Buyer shall have the right to make a public
disclosure, in the form of a press release, public advertisement or otherwise, of such material, non-public information without
the prior approval by the Company, any of its Subsidiaries, or any of its or their respective officers, directors, employees or
agents. No Buyer shall have any liability to the Company, any of its Subsidiaries, or any of its or their respective officers,
directors, employees, stockholders or agents, for any such disclosure. To the extent that the Company delivers any material, non-public
information to a Buyer without such Buyer's consent, the Company hereby covenants and agrees that such Buyer shall not have any
duty of confidentiality to the Company, any of its Subsidiaries or any of their respective officers, directors, employees, affiliates
or agents with respect to, or a duty not to trade on the basis of, such material, non-public information. Subject to the foregoing,
neither the Company, its Subsidiaries nor any Buyer shall issue any press releases or any other public statements with respect
to the transactions contemplated hereby without the prior approval of legal counsel; provided, however, the Company shall be entitled,
without the prior approval of any Buyer, to make any press release or other public disclosure with respect to such transactions
(i) in substantial conformity with the Press Release and the 8-K Filing, or any other filing approved in accordance herewith, and
(ii) in the opinion of the Company’s legal counsel, as is required by applicable law and regulations, or the applicable Eligible
Market on which the Company’s common stock is listed or designated. Unless required by applicable law, without the prior
written consent of the applicable Buyer, the Company shall not (and shall not Knowingly allow any of its Subsidiaries and Affiliates
to) disclose the name of such Buyer in any filing (other than in the Transaction Documents filed as exhibits to the 8-K Filing),
announcement, release or otherwise. Except as provided in the following sentence, notwithstanding anything contained in this Agreement
to the contrary and without implication that the contrary would otherwise be true, the Company expressly acknowledges and agrees
that no Buyer has had, and no Buyer shall have (unless agreed to by a particular Buyer before or after the date hereof in a written
agreement executed by the Company and such particular Buyer), any duty of confidentiality with respect to, or a duty not to trade
on the basis of, any material, non-public information regarding the Company or any of its Subsidiaries. Notwithstanding anything
herein to the contrary except where otherwise set out, the term “Buyer” or “Buyers” in this Section 4(f)
shall exclude the Placement Agent and any officer, director or employee of the Placement Agent or the Company, or of any of their
Subsidiaries.

 

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(g)          Additional
Issuance of Securities. Except as contemplated by the Transaction Documents, the Company agrees that for the period commencing
on the date hereof and ending on the date immediately following the ninetieth (90th) day after the date hereof (the “Restricted
Period”), unless otherwise consented to in writing by each of the Large Investors (as defined below), neither the Company
nor any of its Subsidiaries shall directly or indirectly issue, offer, sell, grant any option or right to purchase, or otherwise
dispose of (or announce any issuance, offer, sale, grant of any option or right to purchase or other disposition of) any Common
Stock or any security or any debt or other instrument convertible or exchangeable or exercisable into Common Stock or which constitutes
(or would constitute but for lack of a fixed exercise or conversion or similar price or if it were not solely cash settled) a “derivative
security” (as defined under the rules and regulations under Section 16 of the 1934 Act) or otherwise an equity-linked or
related security (including, without limitation, any “equity security” (as that term is defined under Rule 405 promulgated
under the 1933 Act) or which does or would otherwise constitute any Option or Convertible Security (as defined in the Warrants)
(any such issuance, offer, sale, grant, disposition or announcement (whether occurring during the Restricted Period or at any time
thereafter) is referred to as a “Subsequent Placement”). Notwithstanding the foregoing, the immediately preceding
sentence in this Section shall not apply in respect of the issuance of

 

(A)     shares
of Common Stock or standard options to purchase Common Stock or other standard equity linked securities (e.g., stock appreciation
rights) to directors, officers, employees or consultants of the Company in their capacity as such pursuant to an Approved Share
Plan (as defined below); provided that (1) all such issuances that are exercisable or vest during the Restricted Period (taking
into account the shares of Common Stock issuable upon exercise of such options and equity linked securities that are exercisable
or vest during the Restricted Period, but not including shares issuable pursuant to Options or Convertible Securities outstanding
as of the date hereof) and are issued after the date hereof pursuant to this clause (A) do not, in the aggregate, exceed more than
the number of shares equal to 6% of the Company’s total outstanding shares of Common Stock following the Final Closing (as
adjusted for any stock split, stock dividend, recapitalization, stock combination, reverse stock split or similar transaction)
of Common Stock or standard options to purchase Common Stock or other standard equity linked securities (e.g., stock appreciation
rights) to directors, officers or employees; (2) the exercise price of any such options is not lowered, none of such options are
amended to increase the number of shares issuable thereunder and none of the terms or conditions of any such options are otherwise
materially changed in any manner that adversely affects any of the Buyers and (3) the issuance price of Common Stock or the exercise
price of any such options is not lower than the higher of (i) $0.20 (as adjusted for any stock split, stock dividend, recapitalization,
stock combination, reverse stock split or similar transaction) or (ii) the closing price of the Company’s Common Stock on
the Principal Market on the date of grant of such Common Stock or option;

 

(B)     shares
of Common Stock issued upon the conversion or exercise of Options or Convertible Securities issued prior to the date hereof to
the extent issued pursuant to their terms as of the date hereof;

 

(C)      the
Common Shares and the Warrants to the extent issued pursuant to the terms contemplated hereby;

 

(D)     the
Warrant Shares to the extent issued pursuant to the terms set forth in the Warrants contemplated by this Agreement as of the date
hereof;

 

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(E)      issuances
of equity to a seller, or in the case of a merger, the shareholders of the target company in such merger, or the officers or employees
thereof, in each case in connection with a bona fide merger, business combination transaction or acquisition of stock or assets
outside of the ordinary course;

 

(F)      a
stock split or other subdivision or combination, or a stock dividend made to all holders of any Company equity on a pro rata basis;
or

 

(G)      issuances
of Common Stock or Convertible Securities in connection with strategic partnerships, joint ventures, licensing, acquisition of
assets or technology, or similar arrangements approved by a majority of the disinterested directors of the Company, provided that
any such issuance shall only be to a Person (or to the equity holders of a Person) which is, itself or through its subsidiaries,
an operating company or an owner of an asset in a business synergistic with the business of the Company and shall provide to the
Company additional benefits in addition to the investment of funds, but shall not include a transaction in which the Company is
issuing securities primarily for the purpose of raising capital or to an entity whose primary business is investing in securities
(each of the foregoing in clauses (A) through (G), collectively the “Excluded Securities”).

 

As used herein, “Large
Investor” means any Buyer that is an institutional investor and such Buyer’s Purchase Price (together with such
Buyer's institutional affiliates), when added to its (together with its institutional affiliates) purchase price paid in the Company’s
November 2015 financing, equals or exceeds $1,000,000. “Approved Share Plan” means any employee benefit plan
which has been approved by the board of directors of the Company prior to or subsequent to the date hereof pursuant to which shares
of Common Stock and equity securities may be issued to any employee, officer, director or consultant for services provided to the
Company in their capacity as such. “Convertible Securities” means any capital stock or other security of the
Company or any of its Subsidiaries that is at any time and under any circumstances directly or indirectly convertible into, exercisable
or exchangeable for, or which otherwise entitles the holder thereof to acquire, any capital stock or other security of the Company
(including, without limitation, Common Stock) or any of its Subsidiaries.

 

(h)          Reservation
of Shares. So long as any of the Warrants remain outstanding, the Company shall take all action necessary to at all times have
authorized, and reserved for the purpose of issuance, the maximum number of shares of Common Stock issuable upon (i) exercise of
all of the Warrants (without regard to any limitations on the exercise of the Warrants set forth therein).

 

(i)          Conduct
of Business. So long as any of the Warrants remain outstanding, the business of the Company and its Subsidiaries shall not
be conducted in violation of any law, ordinance or regulation of any governmental entity in any jurisdiction to which the Company
is subject, except where such violations would not result, either individually or in the aggregate, in a Material Adverse Effect.

 

(j)          Variable
Rate Transaction. During the two year period commencing on the date of the Final Closing, the Company and each Subsidiary shall
be prohibited from effecting, or entering into an agreement to effect, any Subsequent Placement involving a Variable Rate Transaction.
“Variable Rate Transaction” means a transaction in which the Company or any Subsidiary (i) issues or sells any
Convertible Securities either (A) at a conversion, exercise or exchange rate or other price that is based upon and/or varies with
the trading prices of, or quotations for, the shares of Common Stock at any time after the initial issuance of such Convertible
Securities, or (B) with a conversion, exercise or exchange price that is subject to being reset at some future date after the initial
issuance of such Convertible Securities or upon the occurrence of specified or contingent events directly or indirectly related
to the business of the Company or the market for the Common Stock, other than pursuant to a customary “weighted average”
anti-dilution provision or (ii) enters into any agreement (including, without limitation, an equity line of credit) whereby the
Company or any Subsidiary may sell securities at a future determined price (other than standard and customary “preemptive”
or “participation” rights). Each Buyer shall be entitled to obtain injunctive relief against the Company and its Subsidiaries
to preclude any such issuance, which remedy shall be in addition to any right to collect damages.

 

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(k)          Corporate
Existence. So long as any Buyer owns any Warrants, the Company shall not be party to any Fundamental Transaction (as respectively
defined in the Warrants) unless the Company is in compliance with the applicable provisions governing Fundamental Transactions
set forth in the Warrants.

 

(l)          Participation
Right. From the date hereof through the six month anniversary of the Initial Closing Date, neither the Company nor any of its
Subsidiaries shall, directly or indirectly, effect any Subsequent Placement unless the Company shall have first complied with this
Section. The Company acknowledges and agrees that the right set forth in this Section is a right granted by the Company, separately,
to each Buyer.

 

(i)           At
least five (5) Trading Days prior to any proposed or intended Subsequent Placement, the Company shall deliver to each Buyer a written
notice as to whether such Buyer wants to receive material, non-public information about the Company (each such notice, a “Pre-Notice”).
Upon the written request of a Buyer to receive such material, non-public information within three (3) Trading Days after the Company’s
delivery to such Buyer of such Pre-Notice, and only upon a written request by such Buyer, the Company shall promptly, but no later
than one (1) Trading Day after such request, deliver to such Buyer an irrevocable written notice (the “Offer Notice”)
of any proposed or intended issuance or sale or exchange (the “Offer”) of the securities being offered (the
“Offered Securities”) in a Subsequent Placement, which Offer Notice shall (w) identify and describe the Offered
Securities, (x) describe the price and other terms upon which they are to be issued, sold or exchanged, and the number or amount
of the Offered Securities to be issued, sold or exchanged, (y) identify the Persons (if known) to which or with which the Offered
Securities are to be offered, issued, sold or exchanged and (z) offer to issue and sell to or exchange with such Buyers in accordance
with the terms of the Offer up to an aggregate of 100% of the Offered Securities, provided that the number of Offered Securities
which each such Buyer shall have the right to subscribe for under this Section shall be (a) based on such Buyer’s pro rata
portion of the Common Stock purchased hereunder by all Buyers (the “Basic Amount”), and (b) with respect to
each Buyer that elects to purchase its Basic Amount, any additional portion of the Offered Securities attributable to the Basic
Amounts of other Buyers as such Buyer shall indicate it will purchase or acquire should the other Buyers subscribe for less than
their Basic Amounts (the “Undersubscription Amount”).

 

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(ii)          To
accept an Offer, in whole or in part, such Buyer must deliver a written notice to the Company prior to the end of the fifth (5th)
Business Day after such Buyer’s receipt of the Offer Notice (the “Offer Period”), setting forth the portion
of such Buyer’s Basic Amount that such Buyer elects to purchase and, if such Buyer shall elect to purchase all of its Basic
Amount, the Undersubscription Amount, if any, that such Buyer elects to purchase (in either case, the “Notice of Acceptance”).
If the Basic Amounts subscribed for by all Buyers are less than the total of all of the Basic Amounts, then such Buyer who has
set forth an Undersubscription Amount in its Notice of Acceptance shall be entitled to purchase, in addition to the Basic Amounts
subscribed for, the Undersubscription Amount it has subscribed for; provided, however, if the Undersubscription Amounts subscribed
for exceed the difference between the total of all the Basic Amounts and the Basic Amounts subscribed for (the “Available
Undersubscription Amount”), such Buyer who has subscribed for any Undersubscription Amount shall be entitled to purchase
only that portion of the Available Undersubscription Amount as the Basic Amount of such Buyer bears to the total Basic Amounts
of all Buyers that have subscribed for Undersubscription Amounts (but in no event shall it be greater than such Buyer’s specified
Undersubscription Amount), subject to rounding by the Company to the extent it deems reasonably necessary. Notwithstanding the
foregoing, if the Company desires to modify or amend the terms and conditions of the Offer prior to the expiration of the Offer
Period, the Company may deliver to each Buyer a new Offer Notice and the Offer Period shall expire on the fifth (5th)
Business Day after such Buyer’s receipt of such new Offer Notice.

 

(iii)         The
Company shall have ten (10) days from the expiration of the Offer Period above (i) to offer, issue, sell or exchange all or any
part of such Offered Securities as to which a Notice of Acceptance has not been given by a Buyer (the “Refused Securities”)
pursuant to a definitive agreement(s) (the “Subsequent Placement Agreement”), but only to the offerees described
in the Offer Notice (if so described therein) and only upon terms and conditions (including, without limitation, unit prices and
interest rates) that are not more favorable to the acquiring Person or Persons or less favorable to the Company than those set
forth in the Offer Notice and (ii) to publicly announce (a) the execution of such Subsequent Placement Agreement, and (b) either
(x) the consummation of the transactions contemplated by such Subsequent Placement Agreement or (y) the termination of such Subsequent
Placement Agreement, which shall be filed with the SEC on a Current Report on Form 8-K with such Subsequent Placement Agreement
and any documents contemplated therein filed as exhibits thereto.

 

(iv)         In
the event the Company shall propose to sell less than all the Refused Securities (any such sale to be in the manner and on the
terms specified in Section 4(l)(iii) above), then such Buyer may, at its sole option and in its sole discretion, reduce the number
or amount of the Offered Securities specified in its Notice of Acceptance to an amount that shall be not less than the number or
amount of the Offered Securities that such Buyer elected to purchase pursuant to Section 4(n)(iii) above multiplied by a fraction,
(i) the numerator of which shall be the number or amount of Offered Securities the Company actually proposes to issue, sell or
exchange (including Offered Securities to be issued or sold to Buyers pursuant to this Section prior to such reduction) and (ii)
the denominator of which shall be the original amount of the Offered Securities. In the event that any Buyer so elects to reduce
the number or amount of Offered Securities specified in its Notice of Acceptance, the Company may not issue, sell or exchange more
than the reduced number or amount of the Offered Securities unless and until such securities have again been offered to the Buyers
in accordance with Section 4(n)(i) above.

 

(v)          Upon
the closing of the issuance, sale or exchange of all or less than all of the Refused Securities, such Buyer shall acquire from
the Company, and the Company shall issue to such Buyer, the number or amount of Offered Securities specified in its Notice of Acceptance.
The purchase by such Buyer of any Offered Securities is subject in all cases to the preparation, execution and delivery by the
Company and such Buyer of a separate purchase agreement relating to such Offered Securities reasonably satisfactory in form and
substance to such Buyer and its counsel.

 

(vi)         Any
Offered Securities not acquired by a Buyer or other Persons in accordance with this Section may not be issued, sold or exchanged
until they are again offered to such Buyer under the procedures specified in this Agreement.

 

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(vii)        The
Company and each Buyer agree that if any Buyer elects to participate in the Offer, neither the Subsequent Placement Agreement with
respect to such Offer nor any other transaction documents related thereto (collectively, the “Subsequent Placement Documents”)
shall include any term or provision whereby such Buyer shall be required to agree to any restrictions on trading as to any securities
of the Company or be required to consent to any amendment to or termination of, or grant any waiver or release or the like under
or in connection with, any agreement previously entered into with the Company or any instrument received from the Company.

 

(viii)       Notwithstanding
anything to the contrary in this Section and unless otherwise agreed to by such Buyer, the Company shall either confirm in writing
to such Buyer that the transaction with respect to the Subsequent Placement has been abandoned or shall publicly disclose its intention
to issue the Offered Securities, in either case, in such a manner such that such Buyer will not be in possession of any material,
non-public information, by the fifth (5th) Business Day following delivery of the Offer Notice. If by such fifth (5th)
Business Day, no public disclosure regarding a transaction with respect to the Offered Securities has been made, and no notice
regarding the abandonment of such transaction has been received by such Buyer, such transaction shall be deemed to have been abandoned
and such Buyer shall not be in possession of any material, non-public information with respect to the Company or any of its Subsidiaries
and any and all confidentiality or similar obligations under any agreement, whether written or oral, between the Company, any of
its Subsidiaries or any of their respective officers, directors, affiliates, employees or agents, on the one hand, and such Buyer
or any of its affiliates, on the other hand, shall terminate. Should the Company decide to pursue such transaction with respect
to the Offered Securities, the Company shall provide such Buyer with another Offer Notice in accordance with, and subject to, the
terms of this Section and such Buyer will again have the right of participation set forth in this Section. The Company shall not
be permitted to deliver more than one Offer Notice to such Buyer in any sixty (60) day period, except as expressly contemplated
by the last sentence of Section 4(n)(ii).

 

(ix)         The
restrictions contained in this Section shall not apply in connection with the issuance of any Excluded Securities. The Company
shall not circumvent the provisions of this Section by providing terms or conditions to one Buyer that are not provided to all
Buyers.

 

(m)         Use
of Proceeds. The Company shall use the proceeds from the sale of the Securities solely for working capital, sales and marketing
and research and development, but not for (i) the repayment of any outstanding indebtedness of the Company or any of its Subsidiaries
or (ii) the redemption or repurchase of any of its or its Subsidiaries’ equity securities.

 

(n)          Closing
Documents. On or prior to twenty (20) calendar days after the Initial Closing Date, the Company agrees to deliver, or cause
to be delivered, to each of the Large Investors a complete closing set of the executed Transaction Documents, Securities and any
other documents required to be delivered to any party pursuant to Section 6 hereof or otherwise.

 

(o)         Form
D and Blue Sky. The Company agrees to file a Form D with respect to the Securities as
required under Regulation D. The Company shall, on or before each Closing Date, take such action as the Company shall
reasonably determine is necessary in order to obtain an exemption for, or to, qualify the Securities for sale to the Buyers
at each Closing pursuant to this Agreement under applicable securities or “Blue Sky” laws of the states of the
United States (or to obtain an exemption from such qualification), on or prior to each Closing Date. The Company shall make
all filings and reports relating to the offer and sale of the Securities required under applicable securities or “Blue
Sky” laws of the states of the United States following each Closing Date at the expense of the Company.

 

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(p)          Additional
Registration Statements. Except as disclosed in Section 4(r) of the Disclosure Schedule, until the Applicable Date (as
defined below) and at any time thereafter while any Registration Statement is not effective or the prospectus contained therein
is not available for use, the Company shall not file a registration statement under the 1933 Act relating to securities that are
not the Registrable Securities (as defined in the Registration Rights Agreement). “Applicable Date” means the first
date on which the resale by the Buyers of all Registrable Securities is covered by one or more effective Registration Statements
(and each prospectus contained therein is available for use on such date).

 

(q)          Conversion
of the Series B Convertible Preferred Stock. The Company will take all steps necessary to ensure that all outstanding shares
of Series B Convertible Preferred Stock shall convert into shares of the Company’s common stock on or prior to the Initial
Closing Date.

 

(r)          Reduction
in Exercise Price of Warrants. Following the Initial Closing, the Company shall reduce the exercise price of (i) the Series
A Warrants and Series C Warrants issued contemporaneously with the issuance of the Series B Preferred Stock to $0.01 per share
and (ii) the Series E Warrants issued contemporaneously with the issuance of the Series B Preferred Stock to $1.00 per share, in
each case subject to adjustment as provided in such Warrants.

 

(s)          NASDAQ
Listing. Following the effective date of the Reverse Stock Split, the Company shall apply for listing of its Common Stock on
The NASDAQ Capital Market.

 

(t)          FAST
Compliance. The Company covenants and agrees to maintain a transfer agent that is a participant in the FAST program so long
as any Warrants remain outstanding.

 

		5.	REGISTER; TRANSFER AGENT
INSTRUCTIONS; LEGEND.

 

(a)          Register.
The Company or the Company’s Transfer Agent shall maintain at its principal executive offices or the offices of the Company’s
Transfer Agent (or such other office or agency of the Company as it may designate by notice to each holder of Securities), a register
for the Common Shares and the Warrants in which the Company shall record the name and address of the Person in whose name the Common
Shares and the Warrants have been issued (including the name and address of each transferee), the number of Common Shares held
by such Person and the number of Warrant Shares issuable upon exercise of the Warrants held by such Person. Upon reasonable request,
the Company shall keep (or instruct the Transfer Agent to keep) the register open and available at all times during business hours
for inspection of any Buyer or its legal representatives.

 

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(b)          Transfer
Agent Instructions. The Company shall issue irrevocable instructions to its Transfer Agent and any subsequent Transfer Agent
in substantially the form attached hereto as Exhibit B (the “Irrevocable Transfer Agent Instructions”)
to issue certificates or credit shares to the applicable balance accounts at Depository Trust Company (DTC) (as applicable), registered
in the name of each Buyer or its respective nominee(s), for the Warrant Shares in such amounts as specified from time to time
by each Buyer to the Company (not to exceed the amount held by such Buyer at such time) upon the exercise of the Warrants. Except
as provided in this Agreement, the Company represents and warrants that no instruction other than the Irrevocable Transfer Agent
Instructions referred to in this Section, and stop transfer instructions to give effect to Section (e) hereof, will be given by
the Company to its Transfer Agent with respect to the Securities, and that the Securities shall otherwise be freely transferable
on the books and records of the Company, as applicable, to the extent provided in this Agreement and the other Transaction Documents.
If a Buyer effects a sale, assignment or transfer of the Securities in accordance with this Agreement, the Company shall permit
the transfer and shall promptly instruct its transfer agent to issue one or more certificates or credit shares to the applicable
balance accounts at DTC (as applicable) in such name and in such denominations as specified by such Buyer to effect such sale,
transfer or assignment. In the event that such sale, assignment or transfer involves Common Shares or Warrant Shares sold, assigned
or transferred pursuant to an effective registration statement or in compliance with Rule 144, the Transfer Agent shall issue
such shares to such Buyer, assignee or transferee (as the case may be) without any restrictive legend in accordance with Section
5(d) below. The Company acknowledges that a breach by it of its obligations hereunder will cause irreparable harm to a Buyer.
Accordingly, the Company acknowledges that the remedy at law for a breach of its obligations under this Section may be inadequate
and agrees, in the event of a breach or threatened breach by the Company of the provisions of this Section, that a Buyer shall
be entitled, in addition to all other available remedies, to an order and/or injunction restraining any breach and requiring immediate
issuance and transfer, without the necessity of showing economic loss and without any bond or other security being required. The
Company shall cause its counsel to issue the legal opinion referred to in the Irrevocable Transfer
Agent Instructions to the Company’s Transfer Agent on each Effective Date (as defined
in the Registration Rights Agreement). Any fees (with respect to the Transfer Agent, counsel
to the Company or otherwise, but excluding fees incurred by a Buyer in connection with this Section 5) associated with the issuance
of such opinion or the removal of any legends on any of the Securities shall be borne by the Company. 

  

(c)          Legends .
Each Buyer understands that the Securities have been issued (or will be issued in the case of the Warrant Shares) pursuant to
an exemption from registration or qualification under the 1933 Act and applicable state securities laws, and except as set forth
below, the Securities shall bear any legend as required by the “blue sky” laws of any state and a restrictive legend
in substantially the following form (and a stop-transfer order may be placed against transfer of such stock certificates):

 

[NEITHER THE ISSUANCE AND SALE
OF THE SECURITIES REPRESENTED BY THIS CERTIFICATE NOR THE SECURITIES INTO WHICH THESE SECURITIES ARE [EXERCISABLE] HAVE BEEN][THE
SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN] REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE
STATE SECURITIES LAWS. THE SECURITIES MAY NOT BE OFFERED FOR SALE, SOLD, TRANSFERRED OR ASSIGNED (I) IN THE ABSENCE OF (A) AN EFFECTIVE
REGISTRATION STATEMENT FOR THE SECURITIES UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR (B) AN OPINION OF COUNSEL TO THE HOLDER,
THE SUBSTANCE OF WHICH IS REASONABLY ACCEPTABLE TO THE COMPANY, THAT REGISTRATION IS NOT REQUIRED UNDER SAID ACT OR (II) UNLESS
SOLD OR ELIGIBLE TO BE SOLD PURSUANT TO RULE 144 OR RULE 144A UNDER SAID ACT. NOTWITHSTANDING THE FOREGOING, THE SECURITIES MAY
BE PLEDGED IN CONNECTION WITH A BONA FIDE MARGIN ACCOUNT OR OTHER LOAN OR FINANCING ARRANGEMENT SECURED BY THE SECURITIES.

 

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(d)          Removal
of Legends. Certificates evidencing Securities shall not be required to contain the legend set forth in Section 5(c) above
or any other legend (i) if such Securities are registered for resale under the 1933 Act, (ii) following any sale of such Securities
pursuant to Rule 144 (assuming the transferor is not an affiliate of the Company), (iii) in connection with a sale, assignment
or other transfer (other than under Rule 144), provided that such Buyer provides the Company with an opinion of counsel to such
Buyer, in a generally acceptable substance, to the effect that such sale, assignment or transfer of the Securities may be made
without registration under the applicable requirements of the 1933 Act or (iv) if such legend is not required under applicable
requirements of the 1933 Act (including, without limitation, controlling judicial interpretations and pronouncements issued by
the SEC). If a legend is not required pursuant to the foregoing, the Company shall no later than two (2) Trading Days following
the delivery by a Buyer to the Company or the Transfer Agent (with notice to the Company) of a legended certificate representing
such Securities (endorsed or with stock powers attached, signatures guaranteed, and otherwise in form necessary to affect the reissuance
and/or transfer, if applicable), together with any other deliveries from such Buyer as may be required above in this Section and
the Form of Notice attached as Exhibit B to the Registration Rights Agreement, as directed by such Buyer, either: (A) provided
that the Company’s Transfer Agent is participating in the DTC Fast Automated Securities Transfer Program and such Securities
are Common Shares or Warrant Shares, credit the aggregate number of shares of Common Stock to which such Buyer shall be entitled
to such Buyer’s or its designee’s balance account with DTC through its Deposit/Withdrawal at Custodian system or (B)
if the Company’s Transfer Agent is not participating in the DTC Fast Automated Securities Transfer Program, issue and deliver
(via reputable overnight courier) to such Buyer, a certificate representing such Securities that is free from all restrictive and
other legends, registered in the name of such Buyer or its designee (the date by which such credit is so required to be made to
the balance account of such Buyer’s or such Buyer’s nominee with DTC or such certificate is required to be delivered
to such Buyer pursuant to the foregoing is referred to herein as the “Required Delivery Date”). The Company
shall be responsible for the fees of its transfer agent and all DTC fees associated with such issuance. Notwithstanding anything
to the contrary contained herein, no Buyer shall be required to deliver any seller or broker representation letters to the Company,
the Company's transfer agent or any other party in connection with legend removal contemplated by clause (i) in the first sentence
of this paragraph.

 

(e)          Failure
to Timely Deliver; Buy-In. If the Company fails to (i) issue and deliver (or cause to be delivered) to a Buyer by the Required
Delivery Date a certificate representing the Securities so delivered to the Company by such Buyer that is free from all restrictive
and other legends or (ii) following registration on a Registration Statement, credit the balance account of such Buyer’s
or such Buyer’s nominee with DTC for such number of Securities so delivered to the Company, then, in addition to all other
remedies available to such Buyer, the Company shall pay in cash to such Buyer on each day after the Required Delivery Date that
the issuance or credit of such shares is not timely effected an amount equal to 1% of the Exercise Price (as defined in the applicable
Warrant) attributable to the Securities that the issuance or credit of such was not timely effected. In addition to the foregoing,
if the Company fails to so properly deliver such unlegended certificates or so properly credit the balance account of such Buyer’s
or such Buyer’s nominee with DTC by the Required Delivery Date, and if on or after the Required Delivery Date such Buyer
purchases (in an open market transaction or otherwise) shares of Common Stock to deliver in satisfaction of a sale by such Buyer
of shares of Common Stock that such Buyer anticipated receiving from the Company without any restrictive legend, then, in addition
to all other remedies available to such Buyer, the Company shall, within two (2) Trading Days after such Buyer’s request
and in such Buyer’s sole discretion, either (i) pay cash to such Buyer in an amount equal to such Buyer’s total purchase
price (including brokerage commissions, if any) for the shares of Common Stock so purchased (the “Buy-In Price”),
at which point the Company’s obligation to deliver such certificate or credit such Buyer’s balance account shall terminate
and such shares shall be cancelled, or (ii) promptly honor its obligation to deliver to such Buyer a certificate or certificates
or credit such Buyer’s DTC account representing such number of shares of Common Stock that would have been issued if the
Company timely complied with its obligations hereunder and pay cash to such Buyer in an amount equal to the excess (if any) of
the Buy-In Price over the product of (A) such number of shares of Warrant Shares (as the case may be) that the Company was required
to deliver to such Buyer by the Required Delivery Date times (B) the Closing Sale Price (as defined in the Warrants) of the Common
Stock on the Trading Day immediately preceding the Required Delivery Date.

 

		6.	CONDITIONS TO EACH BUYER’S
OBLIGATION TO PURCHASE.

 

(a)          The
obligation of each Buyer hereunder to purchase its applicable Common Shares and the related Warrants at each Closing is subject
to the satisfaction, at or before each Closing Date and in respect of each Closing Date (except as otherwise provided herein),
of each of the following conditions, provided that these conditions are for each Buyer’s sole benefit and may be waived by
such Buyer at any time in its sole discretion by providing the Company with prior written notice thereof:

 

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(i)           The
Company shall have duly executed and delivered to such Buyer each of the Transaction Documents to which it is a party.

 

(ii)          The
Company shall provide to Barbara Glenns, Esq., for and on behalf of the Placement Agents (“Ms. Glenns”) and
any Buyer who so requests beforehand, satisfactory evidence from the Secretary of State of its jurisdiction of formation that the
Company has been formed and is in good standing and shall deliver to such Buyer a certificate evidencing the formation and good
standing of the Company in its jurisdiction of formation issued by the Secretary of State (or comparable office) of such jurisdiction
of formation as of a date within ten (10) days of the Initial Closing Date.

 

(iii)         The
Company shall have delivered to Ms. Glenns and any Buyer who so requests beforehand, a copy of a certificate evidencing the Company’s
qualification as a foreign corporation and good standing issued by the Secretary of State (or comparable office) of each jurisdiction
in which the Company is qualified to conduct business at the Initial Closing.

 

(iv)         The
Company shall have delivered to Ms. Glenns and any Buyer who so requests beforehand, a copy of a certified copy of the true and
correct Certificate of Incorporation as of the date hereof and shall deliver a certified copy from the Nevada Secretary of State
within ten (10) days of the Initial Closing Date.

 

(v)         The
Company shall have delivered to Ms. Glenns and any Buyer who so requests beforehand, a copy of a certificate, in the form reasonably
acceptable to such Buyer, executed by the Secretary of the Company and dated as of the Initial Closing Date, as to (i) the resolutions
consistent with Section 3(b) as adopted by the Company’s board of directors in a form reasonably acceptable to such Buyer,
(ii) Certificate of Incorporation, and (iii) the Bylaws of the Company, in each case, as in effect at the Initial Closing.

 

(vi)         Each
and every representation and warranty of the Company shall be true and correct in all material respects as of the date when made
and as of the respective Closing Date as though originally made at that time (except that (1) representations and warranties that
speak as of a specific date shall be true and correct in all material respects as of such date and (2) representations and warranties
that are qualified by material, Material Adverse Effect or other similar materiality qualifiers shall be true and correct in all
respects) and the Company shall have performed, satisfied and complied in all material respects with the covenants, agreements
and conditions required to be performed, satisfied or complied with by the Company at or prior to the respective Closing Date,
including, without limitation the issuance of all Securities prior to the date of such Closing as required by the Transaction Documents
and the Company has a sufficient number of duly authorized shares of Common Stock reserved for issuance as may be required to fulfill
its obligations pursuant to the Transaction Documents. Such Buyer shall have received a certificate, executed by the Secretary
of the Company, dated as of the Initial Closing Date, to the foregoing effect and as to such other matters as may be reasonably
requested by such Buyer in the form reasonably acceptable to such Buyer.

  

(vii)        The
Company shall have delivered to Ms. Glenns and any Buyer who so requests beforehand, a report from the Company’s Transfer
Agent identifying the number of shares of Common Stock outstanding on the Trading Day immediately prior to the Initial Closing.

 

(viii)      The
Common Stock (I) shall be designated for quotation or listed on the Principal Market and (II) shall not have been suspended, as
of each Closing Date, by the SEC or the Principal Market from trading or quotation on the Principal Market nor shall suspension
by the SEC or the Principal Market have been threatened, as of each Closing Date, either (A) in writing by the SEC or the Principal
Market or (B) by falling below the minimum maintenance requirements, if any, of the Principal Market.

 

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(ix)         The
Company shall have obtained all governmental, regulatory or third party consents and approvals, if any, necessary for the sale
of the Securities, including without limitation, those required by the Principal Market.

 

(x)          No
statute, rule, regulation, executive order, decree, ruling or injunction shall have been enacted, entered, promulgated or endorsed
by any court or governmental authority of competent jurisdiction that prohibits the consummation of any of the transactions contemplated
by the Transaction Documents, and no actions, suits or proceedings shall be in progress or pending by any Person that seeks to
enjoin, prohibit or otherwise adversely affect any of the transactions contemplated by the Transaction Documents.

 

(xi)         Since
the date of execution of this Agreement, no event or series of events shall have occurred that reasonably would have or result
in a Material Adverse Effect and the Company has not filed for nor is it subject to any bankruptcy, insolvency, reorganization
or liquidation proceedings or other proceedings for relief under any bankruptcy law or any law for the relief of debtors instituted
by or against the Company.

 

(xii)        The
Company shall have delivered to Ms. Glenns, such other documents, instruments or certificates relating to the transactions contemplated
by this Agreement reasonably required to consummate the transactions contemplated hereby.

 

(xiii)       Such
Buyer shall have received the opinion of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C., the Company’s counsel, dated
as of Initial Closing Date, in the form previously agreed to by the Company and Ms. Glenns.

 

(xiv)      A
copy of the Irrevocable Transfer Agent Instructions, in the form previously agreed upon by the Company, the Transfer Agent and
Ms. Glenns, and which have been delivered to and acknowledged in writing by the Company and Transfer Agent shall be delivered to
Ms. Glenns and any Buyer who so requests beforehand.

 

		7.	TERMINATION.

 

In the event that the
Initial Closing shall not have occurred with respect to a Buyer within three (3) Trading Days after the date hereof, then such
Buyer shall have the right to terminate its obligations under this Agreement with respect to itself at any time on or after the
close of business on such date without liability of such Buyer to any other party; provided, however, (i) the right to terminate
its obligations under this Agreement pursuant to this Section shall not be available to such Buyer if the failure of the transactions
contemplated by this Agreement to have been consummated by such date is the result of such Buyer’s breach of this Agreement
and (ii) the abandonment of the sale and purchase of the Common Shares and the Warrants shall be applicable only to such Buyer
providing such written notice, provided further that no such termination shall affect any obligation of the Company under this
Agreement to reimburse such Buyer for the expenses described in Section 4(d) above. Notwithstanding anything to the contrary above,
nothing contained in this Section shall be deemed to release any party from any liability for any breach by such party of the terms
and provisions of this Agreement or the other Transaction Documents or to impair the right of any party to compel specific performance
by any other party of its obligations under this Agreement or the other Transaction Documents.

 

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		8.	MISCELLANEOUS.

 

(a)          Governing
Law; Jurisdiction; Jury Trial. All questions concerning the construction, validity, enforcement and interpretation of this
Agreement shall be governed by the internal laws of the State of New York. Each party hereby irrevocably submits to the exclusive
jurisdiction of the state and federal courts sitting in New York County, New York, for the adjudication of any dispute hereunder
or in connection herewith or with any transaction contemplated hereby or discussed herein, and hereby irrevocably waives, and agrees
not to assert in any suit, action or proceeding, any claim that it is not personally subject to the jurisdiction of any such court,
that such suit, action or proceeding is brought in an inconvenient forum or that the venue of such suit, action or proceeding is
improper. Each party hereby irrevocably waives personal service of process and consents to process being served in any such suit,
action or proceeding by mailing a copy thereof to such party at the address for such notices to it under this Agreement and agrees
that such service shall constitute good and sufficient service of process and notice thereof. Nothing contained herein shall (i)
limit or be deemed to limit in any way any right to serve process in any manner permitted by law or (ii) operate, or be deemed
to operate, to preclude any Buyer from bringing suit or taking other legal action against the Company in any other jurisdiction
to collect on the Company’s obligations to such Buyer or to enforce a judgment or other court ruling in favor of such Buyer
or (iii) limit, or be deemed to limit, any provision of the Warrants which is contrary to the above. EACH PARTY HEREBY IRREVOCABLY
WAIVES ANY RIGHT IT MAY HAVE TO, AND AGREES NOT TO REQUEST, A JURY TRIAL FOR THE ADJUDICATION OF ANY DISPUTE HEREUNDER OR IN CONNECTION
WITH OR ARISING OUT OF THIS AGREEMENT OR ANY TRANSACTION CONTEMPLATED HEREBY.

 

(b)          Counterparts.
This Agreement may be executed in two or more identical counterparts, all of which shall be considered one and the same agreement
and shall become effective when counterparts have been signed by each party and delivered to the other party. In the event that
any signature is delivered by facsimile transmission or by an e-mail which contains a portable document format (.pdf) file of an
executed signature page, such signature page shall create a valid and binding obligation of the party executing (or on whose behalf
such signature is executed) with the same force and effect as if such signature page were an original thereof.

 

(c)          Headings;
Gender; Certain Meanings. The headings of this Agreement are for convenience of reference and shall not form part of, or affect
the interpretation of, this being deemed to include the masculine, feminine, neuter, singular and plural forms thereof. The terms
“including,” “includes,” “include” and words of like import shall be construed broadly as if
followed by the words “without limitation.” The terms “herein,” “hereunder,” “hereof”
and words of like import refer to this entire Agreement instead of just the provision in which they are found. When used herein,
the words “law,” “rule,” “regulation” and the like means all applicable laws, rules and regulations,
domestic or foreign, state, provincial, local or self-regulatory, including without limitation as to all applicable laws, rules
and regulations of or related to the United States, applicable states, the SEC, and the Principal Market.

 

(d)          Severability.
If any provision of this Agreement is prohibited by law or otherwise determined to be invalid or unenforceable by a court of competent
jurisdiction, the provision that would otherwise be prohibited, invalid or unenforceable shall be deemed amended to apply to the
broadest extent that it would be valid and enforceable, and the invalidity or unenforceability of such provision shall not affect
the validity of the remaining provisions of this Agreement so long as this Agreement as so modified continues to express, without
material change, the original intentions of the parties as to the subject matter hereof and the prohibited nature, invalidity or
unenforceability of the provision(s) in question does not substantially impair the respective expectations or reciprocal obligations
of the parties or the practical realization of the benefits that would otherwise be conferred upon the parties. The parties will
endeavor in good faith negotiations to replace the prohibited, invalid or unenforceable provision(s) with a valid provision(s),
the effect of which comes as close as possible to that of the prohibited, invalid or unenforceable provision(s).

 

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(e)          Entire
Agreement; Amendments. Except with regards to any confidentiality or non-disclosure agreement entered into between the Buyers,
the Company, their Affiliates and Persons acting on their behalf in connection with the transactions contemplated hereunder, this
Agreement, the other Transaction Documents and the schedules and exhibits attached hereto and thereto and the instruments referenced
herein and therein supersede all other prior oral or written agreements between the Buyers, the Company, their Affiliates and Persons
acting on their behalf solely with respect to the matters contained herein and therein, and this Agreement, the other Transaction
Documents, the schedules and exhibits attached hereto and thereto and the instruments referenced herein and therein contain the
entire understanding of the parties solely with respect to the matters covered herein and therein; provided, however, nothing contained
in this Agreement or any other Transaction Document shall (or shall be deemed to), (i) have any effect on any agreements any Buyer
has entered into with the Company or any of its Subsidiaries prior to the date hereof with respect to any prior investment made
by such Buyer in the Company or (ii) waive, alter, modify or amend in any respect any obligations of the Company or any of its
Subsidiaries, or any rights of or benefits to any Buyer or any other Person, in any agreement entered into prior to the date hereof
between or among the Company and/or any of its Subsidiaries and any Buyer and all such agreements shall continue in full force
and effect. Except as specifically set forth herein or therein, neither the Company nor any Buyer makes any representation, warranty,
covenant or undertaking with respect to such matters. For clarification purposes, the Recitals are part of this Agreement. No provision
of this Agreement may be waived, modified, supplemented or amended except in a written instrument signed, in the case of an amendment,
by (i) the Company, (ii) the Buyers, including the Large Investors, who own at least 50% of the outstanding Common Shares, and
(iii) as long as it is a holder of Securities, each of the Large Investors (or, if a Large Investor
no longer holds Securities because it has transferred such shares to an “affiliate” (as defined in Rule 405 promulgated
under the U.S. Securities Act of 1933, as amended), such affiliate), and in the case of a waiver, by the party against whom
enforcement of any such waived provision is sought; provided, that if any amendment, modification or waiver disproportionately
and adversely impacts a Buyer, the consent of such Buyer shall also be required. No waiver shall be effective unless it is in writing
and signed by an authorized representative of the waiving party. Any amendment or waiver effected in accordance with this Section
shall be binding upon each Buyer. No such amendment shall be effective to the extent that it applies to less than all of the Buyers.
No consideration shall be offered or paid to any Person to amend or consent to a waiver or modification of any provision of any
of the Transaction Documents unless the same consideration also is offered to all of the parties to the Transaction Documents,
all holders of Common Shares or all holders of the Warrants (as the case may be). Except as provided in Schedule 3(f) of
the Disclosure Schedule, the Company has not, directly or indirectly, made any agreements with any Buyers relating to the terms
or conditions of the transactions contemplated by the Transaction Documents except as set forth in the Transaction Documents. Without
limiting the foregoing, the Company confirms that, except as set forth in this Agreement, no Buyer has made any commitment or promise
or has any other obligation to provide any financing to the Company, any Subsidiary or otherwise. As a material inducement for
each Buyer to enter into this Agreement, the Company expressly acknowledges and agrees that (i) no due diligence investigation
conducted by a Buyer or its advisors, if any, or its representatives shall affect such Buyer’s right to rely on, or modify
or qualify any of, the Company’s representations and warranties contained in this Agreement or any other Transaction
Document, and (ii) unless a provision of this Agreement or any other Transaction Document is expressly preceded by “except
as disclosed in the SEC Reports” or “except as disclosed in the SEC Documents” (or similar language), nothing
contained in any of the SEC Reports or SEC Documents (as applicable) shall affect such Buyer’s right to rely on, or modify
or qualify any of, the Company’s representations and warranties contained in this Agreement or any other Transaction Document.

 

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(f)          Notices.
Any notices, consents, waivers or other communications required or permitted to be given under the terms of this Agreement must
be in writing and will be deemed to have been delivered: (i) upon receipt, when delivered personally; (ii) upon receipt, when sent
by facsimile (provided confirmation of transmission is mechanically or electronically generated and kept on file by the sending
party); (iii) when sent, if sent by e-mail (provided that such sent e-mail is kept on file (whether electronically or otherwise)
by the sending party and the sending party does not receive an automatically generated message from the recipient’s e-mail
server that such e-mail could not be delivered to such recipient); and (iv) one (1) Business Day after deposit with an overnight
courier service with next day delivery specified, in each case, properly addressed to the party to receive the same. The addresses
and facsimile numbers and email addresses for such communications shall be:

 

If to the Company:

 

Neurotrope, Inc.

205 East 42nd Street,
20th Floor

New York, NY 10017

Telephone: 

Facsimile: 

Email: 

Attention:

 

With a copy (for informational
purposes only) to:

 

Mintz, Levin, Cohn, Ferris, Glovsky
and Popeo, P.C.

666 Third Avenue

New York, New York 10017

Telephone: 

Facsimile: 

Email:

Attention:

 

If to the Transfer Agent:

 

Philadelphia Stock Transfer, Inc.

2320 Haverford Rd.

Suite 230

Ardmore, PA 19003

Telephone: 

Facsimile: 

Email:

Attention: 

 

If to a Buyer, to its address and facsimile
number set forth on the Schedule of Buyers, with copies to such Buyer’s representatives as set forth on the Schedule of Buyers,

 

    - 33 -

     

    

 

or to such other address and/or facsimile
number and/or to the attention of such other Person as the recipient party has specified by written notice given to each other
party five (5) days prior to the effectiveness of such change. Written confirmation of receipt (A) given by the recipient of such
notice, consent, waiver or other communication, (B) mechanically or electronically generated by the sender’s facsimile machine
containing the time, date, recipient facsimile number and an image of the first page of such transmission or (C) provided by an
overnight courier service shall be rebuttable evidence of personal service, receipt by facsimile or receipt from an overnight courier
service in accordance with clause (i), (ii) or (iii) above, respectively. A copy of the e-mail transmission containing the time,
date and recipient e-mail address shall be rebuttable evidence of receipt by e-mail in accordance with clause (iii) above.

 

(g)          Successors
and Assigns. This Agreement shall be binding upon and inure to the benefit of the parties and their respective successors and
assigns, including, as contemplated below, any assignee of any of the Securities. The Company shall not assign this Agreement or
any rights or obligations hereunder without the prior written consent of each of the Buyers. A Buyer may assign some or all of
its rights hereunder in connection with any transfer of any of its Securities without the consent of the Company, in which event
such assignee shall be deemed to be a Buyer hereunder with respect to such assigned rights.

 

(h)          No
Third Party Beneficiaries. This Agreement is intended for the benefit of the parties hereto and their respective permitted
successors and assigns, and is not for the benefit of, nor may any provision hereof be enforced by, any other Person, other than
the Buyer Indemnitees referred to in Section 8(k).

 

(i)          Survival.
The representations, warranties, agreements and covenants shall survive each Closing. Each Buyer shall be responsible only for
its own representations, warranties, agreements and covenants hereunder.

 

(j)          Further
Assurances. Each party shall do and perform, or cause to be done and performed, all such further acts and things, and shall
execute and deliver all such other agreements, certificates, instruments and documents, as any other party may reasonably request
in order to carry out the intent and accomplish the purposes of this Agreement and the consummation of the transactions contemplated
hereby.

 

    - 34 -

     

    

  

		(k)	Indemnification.

 

(i)          In
consideration of each Buyer’s execution and delivery of the Transaction Documents and acquiring the Securities thereunder
and in addition to all of the Company’s other obligations under the Transaction Documents but subject to the provisions of
this Section 8(k), the Company shall defend, protect, indemnify and hold harmless each Buyer and all of his, her or its partners,
members, officers, directors, employees and direct or indirect investors and any of the foregoing Persons’ agents or other
representatives (including, without limitation, those retained in connection with the transactions contemplated by this Agreement)
(collectively, the “Indemnitees”) from and against any and all actions, causes of action, suits, claims, losses, costs,
penalties, fees, liabilities and damages, and expenses in connection therewith (irrespective of whether any such Indemnitee is
a party to the action for which indemnification hereunder is sought), and including reasonable attorneys’ fees and disbursements
(the “Indemnified Liabilities”), incurred by any Indemnitee as a result of, or arising out of, or relating to (a) any
material misrepresentation or material breach of any representation or warranty made by the Company in any of the Transaction Documents,
(b) any material breach of any covenant, agreement or obligation of the Company contained in any of the Transaction Documents,
(c) any cause of action, suit or claim brought or made against such Indemnitee by a third party (including for these purposes a
derivative action brought on behalf of the Company) and arising out of or resulting from (i) the execution, delivery, performance
or enforcement of any of the Transaction Documents, (ii) any transaction financed or to be financed in whole or in part, directly
or indirectly, with the proceeds of the issuance of the Securities, (iii) any disclosure properly made by such Buyer pursuant to
Section 4(h), or (iv) the status of such Buyer as an investor in the Company pursuant to the transactions contemplated by the Transaction
Documents. To the extent that the foregoing undertaking by the Company may be unenforceable for any reason, the Company shall make
the maximum contribution to the payment and satisfaction of each of the Indemnified Liabilities which is permissible under applicable
law. Notwithstanding anything to the contrary in this Agreement, the Company will not be liable to any Indemnitee under this Agreement
(x) to the extent, but only to the extent that a loss, claim, damage or liability is attributable to any Indemnitee’s material
breach of any of the representations, warranties, covenants or agreements made by such Indemnitee in this Agreement or in the other
Transaction Documents; (y) for any Indemnified Liabilities arising after the date that none of the Shares or Warrants are outstanding
with respect to such Indemnitee.

 

(ii)         Promptly
after receipt by an Indemnitee under this Section of notice of the commencement of any action or proceeding (including any governmental
action or proceeding) involving an Indemnified Liability, such Indemnitee shall, if a claim in respect thereof is to be made against
the Company under this Section, promptly deliver to the Company a written notice of the commencement thereof, and the Company shall
have the right to participate in, and, to the extent the Company so desires, to assume control of the defense thereof with counsel
mutually satisfactory to the Company and the Indemnitee; provided, however, that an Indemnitee shall have the right to retain its
own counsel with the reasonable fees and expenses of such counsel to be paid by the Company if: (i) the Company has agreed in writing
to pay such fees and expenses; (ii) the Company shall have failed promptly to assume the defense of such Indemnified Liability
and to employ counsel reasonably satisfactory to such Indemnitee in any such Indemnified Liability; or (iii) the named parties
to any such Indemnified Liability (including any impleaded parties) include both such Indemnitee and the Company, and such Indemnitee
shall have been advised by counsel that a conflict of interest is likely to exist if the same counsel were to represent such Indemnitee
and the Company (in which case, if such Indemnitee notifies the Company in writing that it elects to employ separate counsel at
the expense of the Company, then the Company shall not have the right to assume the defense thereof and such counsel shall be at
the expense of the Company), provided further, that in the case of clause (iii) above the Company shall not be responsible for
the reasonable fees and expenses of more than one (1) separate legal counsel for such Indemnitee. The Indemnitee shall reasonably
cooperate with the Company in connection with any negotiation or defense of any such action or Indemnified Liability by the Company
and shall furnish to the Company all information reasonably available to the Indemnitee which relates to such action or Indemnified
Liability. The Company shall keep the Indemnitee reasonably apprised at all times as to the status of the defense or any settlement
negotiations with respect thereto. The Company shall not be liable for any settlement of any action, claim or proceeding effected
without its prior written consent, provided, however, that the Company shall not unreasonably withhold, delay or condition its
consent. The Company shall not, without the prior written consent of the Indemnitee, such consent not to be unreasonably withheld,
conditioned or delayed, consent to entry of any judgment or enter into any settlement or other compromise which does not include
as an unconditional term thereof the giving by the claimant or plaintiff to such Indemnitee of a release from all liability in
respect to such Indemnified Liability or litigation, and such settlement shall not include any admission as to fault on the part
of the Indemnitee. Following indemnification as provided for hereunder, the Company shall be subrogated to all rights of the Indemnitee
with respect to all third parties, firms or corporations relating to the matter for which indemnification has been made. The failure
to deliver written notice to the Company within a reasonable time of the commencement of any such action shall not relieve the
Company of any liability to the Indemnitee under this Section, except to the extent that the Company is materially and adversely
prejudiced in its ability to defend such action. 

 

(iii)        The
indemnification required by this Section shall be made by periodic payments of the amount thereof during the course of the investigation
or defense, within a reasonable amount of time after bills are received or Indemnified Liabilities are incurred.

 

    - 35 -

     

    

  

(iv)        The
indemnity agreement contained herein shall be in addition to (A) any cause of action or similar right of the Indemnitee against
the Company or others, and (B) any liabilities the Company may be subject to pursuant to the law. 

 

(l)          Construction.
The language used in this Agreement will be deemed to be the language chosen by the parties to express their mutual intent, and
no rules of strict construction will be applied against any party. No specific representation or warranty shall limit the generality
or applicability of a more general representation or warranty. Each and every reference to share prices, shares of Common Stock
and any other numbers in this Agreement that relate to the Common Stock shall be automatically adjusted for stock splits, stock
combinations and other similar transactions that occur with respect to the Common Stock after the date of this Agreement.

 

(m)          Remedies.
Each Buyer and each holder of any Securities shall have all rights and remedies set forth in the Transaction Documents and all
rights and remedies which such holders have been granted at any time under any other agreement or contract and all of the rights
which such holders have under any law. Any Person having any rights under any provision of this Agreement shall be entitled to
enforce such rights specifically (without posting a bond or other security), to recover damages by reason of any breach of any
provision of this Agreement and to exercise all other rights granted by law. Furthermore, the Company recognizes that in the event
that it fails to perform, observe, or discharge any or all of its obligations under the Transaction Documents, any remedy at law
may prove to be inadequate relief to the Buyers. The Company therefore agrees that the Buyers shall be entitled to seek specific
performance and/or temporary, preliminary and permanent injunctive or other equitable relief from any court of competent jurisdiction
in any such case without the necessity of proving actual damages and without posting a bond or other security.

 

(n)          Withdrawal
Right. Notwithstanding anything to the contrary contained in (and without limiting any similar provisions of) the Transaction
Documents, whenever any Buyer exercises a right, election, demand or option under a Transaction Document and the Company does not
timely perform its related obligations within the periods therein provided, then such Buyer may rescind or withdraw, in its sole
discretion from time to time upon written notice to the Company, any relevant notice, demand or election in whole or in part without
prejudice to its future actions and rights.

 

    - 36 -

     

    

  

(o)          Independent
Nature of Buyers’ Obligations and Rights. The obligations of each Buyer under the Transaction Documents are several and
not joint with the obligations of any other Buyer, and no Buyer shall be responsible in any way for the performance of the obligations
of any other Buyer under any Transaction Document. Nothing contained herein or in any other Transaction Document, and no action
taken by any Buyer pursuant hereto or thereto, shall be deemed to constitute the Buyers as, and the Company acknowledges that the
Buyers do not so constitute, a partnership, an association, a joint venture or any other kind of group or entity, or create a presumption
that the Buyers are in any way acting in concert or as a group or entity with respect to such obligations or the transactions contemplated
by the Transaction Documents or any matters, and the Company acknowledges that the Buyers are not acting in concert or as a group,
and the Company shall not assert any such claim, with respect to such obligations or the transactions contemplated by the Transaction
Documents. The decision of each Buyer to purchase Securities pursuant to the Transaction Documents has been made by such Buyer
independently of any other Buyer. Each Buyer acknowledges that no other Buyer has acted as agent for such Buyer in connection with
such Buyer making its investment hereunder and that no other Buyer will be acting as agent of such Buyer in connection with monitoring
such Buyer’s investment in the Securities or enforcing its rights under the Transaction Documents. The Company and each Buyer
confirms that each Buyer has independently participated with the Company in the negotiation of the transaction contemplated hereby
with the advice of its own counsel and advisors. Each Buyer shall be entitled to independently protect and enforce its rights,
including, without limitation, the rights arising out of this Agreement or out of any other Transaction Documents, and it shall
not be necessary for any other Buyer to be joined as an additional party in any proceeding for such purpose. The use of a single
agreement to effectuate the purchase and sale of the Securities contemplated hereby was solely in the control of the Company, not
the action or decision of any Buyer, and was done solely for the convenience of the Company and not because it was required or
requested to do so by any Buyer. It is expressly understood and agreed that each provision contained in this Agreement and in each
other Transaction Document is between the Company and a Buyer, solely, and not between the Company and the Buyers collectively
and not between and among the Buyers.

 

(p)          Payment
Set Aside; Currency. To the extent that the Company makes a payment or payments to any Buyer hereunder or pursuant to any of
the other Transaction Documents or any of the Buyers enforce or exercise their rights hereunder or thereunder, and such payment
or payments or the proceeds of such enforcement or exercise or any part thereof are subsequently invalidated, declared to be fraudulent
or preferential, set aside, recovered from, disgorged by or are required to be refunded, repaid or otherwise restored to the Company,
a trustee, receiver or any other Person under any law (including, without limitation, any bankruptcy law, foreign, state or federal
law, common law or equitable cause of action), then to the extent of any such restoration the obligation or part thereof originally
intended to be satisfied shall be revived and continued in full force and effect as if such payment had not been made or such enforcement
or setoff had not occurred. Unless otherwise expressly indicated, all dollar amounts referred to in this Agreement and the other
Transaction Documents are in United States Dollars (“U.S. Dollars”), and all amounts owing under this Agreement
and all other Transaction Documents shall be paid in U.S. Dollars. All amounts denominated in other currencies (if any) shall be
converted in the U.S. Dollar equivalent amount in accordance with the Exchange Rate on the date of calculation. “Exchange
Rate” means, in relation to any amount of currency to be converted into U.S. Dollars pursuant to this Agreement, the
U.S. Dollar exchange rate as published in the Wall Street Journal on the relevant date of calculation.

 

(q)          Potential
Conflicts. The Placement Agents, their subagents, employees, legal counsel and/or their respective Affiliates, principals,
representatives or employees may now or hereafter own shares of the Company.

 

(r)          DTC
Accounts. Notwithstanding anything to the contrary in this Agreement, the Company shall not be obligated herein to credit any
restricted securities, including any Warrant Shares if so restricted, to the Buyer’s DTC account, and any obligation hereunder
to credit shares to a Buyer’s DTC account shall only apply to unrestricted securities.

 

(s)          Disclosure.
Upon delivery by the Company of any notice in accordance with the terms of the Transaction Documents, unless (i) the Company has
in good faith determined that the matters relating to such notice do not constitute material, nonpublic information relating to
the Company or its Subsidiaries or (ii) with respect to all Buyers receiving such notice, the Company and each such Buyer are
parties to a confidentiality agreement covering the information in such notice, the Company shall within two (2) Business Days
after any such receipt or delivery publicly disclose such material, nonpublic information on a Current Report on Form 8-K or otherwise.
In the event that the Company believes that a notice contains material, nonpublic information relating to the Company or its Subsidiaries,
the Company so shall indicate to such Holder contemporaneously with delivery of such notice, and in the absence of any such indication,
the Holder shall be allowed to presume that all matters relating to such notice do not constitute material, nonpublic information
relating to the Company or its Subsidiaries.

  

[signature page follows]

 

    - 37 -

     

    

 

IN WITNESS WHEREOF, Buyer and the
Company have caused their respective signature page to this Agreement to be duly executed as of the date first written above.

 

	 	COMPANY:
	 	 
	 	NEUROTROPE, INC.
	 	 
	 	By:	/s/ Robert Weinstein
	 	 	Name: Robert Weinstein
	 	 	Title:  Chief Financial Officer, Executive Vice President, Secretary and Treasurer

 

[SEE “NEUROTROPE, INC. OMNIBUS SIGNATURE
PAGE TO

SECURITIES PURCHASE AGREEMENT AND

REGISTRATION RIGHTS AGREEMENT”

FOR SIGNATURE PAGES FOR BUYERS.]

 

     

     

    

 

SCHEDULE OF DEFINITIONS

 

As used in the Agreement, the following
terms shall have the meanings set forth below:

 

		a)	“1933 Act” means the Securities Act of 1933, as amended.

 

		b)	“Registrable Securities” shall have the meaning as defined in the Registration
Rights Agreement.

 

		c)	“Trading Day” means, as applicable, (x) with respect to all price determinations
relating to the Common Stock, any day on which the Common Stock is traded on the Principal Market, or, if the Principal Market
is not the principal trading market for the Common Stock, then on the principal securities exchange or securities market on which
the Common Stock is then traded, provided that “Trading Day” shall not include any day on which the Common Stock is
scheduled to trade on such exchange or market for less than 4.5 hours or any day that the Common Stock is suspended from trading
during the final hour of trading on such exchange or market (or if such exchange or market does not designate in advance the closing
time of trading on such exchange or market, then during the hour ending at 4:00:00 p.m., New York time) or (y) with respect to
all determinations other than price determinations relating to the Common Stock, any day on which The New York Stock Exchange (or
any successor thereto) is open for trading of securities.

 

		d)	“Transfer Agent” shall mean the transfer agent of the Company from time-to-time.

 

As used in the Agreement, the following
terms shall have the meaning set forth in the corresponding Section below:

 

	Term	 	Section
	1934 Act	 	2(d)
	8-K filing	 	4(f)
	Additional Buyer	 	1(c)(ii)
	Additional Securities	 	1(c)(ii)
	Affiliate	 	3(f)
	Applicable Date	 	4(r)
	Approved Share Plan	 	4(g)
	Available Undersubscription Amount	 	4(l)(ii)
	Basic Amount	 	4(l)(i)
	BHCA	 	3(hh)
	Business Day	 	1(c)(i)
	Buy-In Price	 	5(e)
	Bylaws	 	3(q)
	Certificate of Incorporation	 	3(q)
	Closing	 	1(c)(i)
	Contingent Obligation	 	3(r)
	Convertible Securities	 	4(g)
	Disclosure Schedules	 	3
	Eligible Market	 	4(c)
	Environmental Laws	 	3(x)
	Escrow Agent	 	1(a)
	Exchange Rate	 	8(p)
	Excluded Securities	 	4(g)(vii)
	Federal Reserve	 	3(hh)
	Fundamental Transaction	 	4(k)
	Hazardous Materials	 	3(x)

 

     

     

    

 

	Indebtedness	 	3(r)
	Indemnified Liabilities	 	8(k)
	Indemnitees	 	8(k)
	Initial Closing Date	 	1(c)(i)
	Initial Closing	 	1(c)(i)
	Insolvent	 	3(k)
	Intellectual Property Rights	 	3(w)
	Irrevocable Transfer Agent Instructions	 	5(b)
	Knowledge and Knowingly	 	2(d)
	Large Investor	 	4(g)
	Material Adverse Effect	 	3(a)
	Ms. Glenns	 	6(a)(ii)
	Notice of Acceptance	 	4(l)(ii)
	Offer Notice	 	4(l)(i)
	Offer Period	 	4(l)(ii)
	Offer	 	4(l)(i)
	Offered Securities	 	4(l)(i)
	Person	 	3(r)
	Placement Agent	 	4(d)
	Pre-Notice	 	4(l)(i)
	Press Release	 	4(f)
	Principal Market	 	3(d)
	Purchase Price	 	1(b)
	Refused Securities	 	4(l)(iii)
	Registration Rights Agreement	 	2(e)
	Reporting Period	 	4(a)
	Required Delivery Date	 	5(d)
	Restricted Period	 	4(g)
	Rule 144	 	2(e)
	SEC Documents	 	2(j)
	SEC Reports	 	3(j)
	SEC	 	3(b)
	Securities	 	Recitals
	Short Sales	 	2(d)
	Subsequent Placement Agreement	 	4(l)(iii)
	Subsequent Placement Documents	 	4(l)(vii)
	Subsequent Placement	 	4(g)
	Subsidiaries	 	3(a)
	Trading Affiliates	 	2(d)
	Transaction Documents	 	3(b)
	U.S. Dollars	 	8(p)
	U.S. Person	 	2(g)
	Undersubscription Amount	 	4(l)(i)
	Unit(s)	 	1(b)
	Variable Rate Transaction	 	4(j)
	Warrant Shares	 	Recitals
	Warrants	 	Recitals

 

     

     

    

 

SCHEDULE OF ADDITIONAL RISK FACTORS

 

		·	Buyers may lose all of their investment. An investment in the Securities is subject to investment
risk, including the possible loss of the entire amount that the Buyers invest.

		·	Shares of Common Stock may be sold in the market following the offering, which may depress the
market price for the Common Stock (including shares issued upon the exercise of options and warrants and those shares of Common
Stock issued upon conversion of the Company’s outstanding shares of Series B Convertible Preferred Stock).

		·	Except as otherwise set forth in the Warrants, Buyers of the Warrants will have no rights as a
common stockholder until they acquire the Company’s Common Stock.

		·	The Company has broad discretion in the use of the proceeds pursuant to this Agreement and, despite
the Company’s efforts, the Company may use the proceeds in a manner that does not improve its operating results or increase
the value of your investment.

		·	The Company’s reverse stock split to be effected following Closing may have the effect of
depressing the market price of the Company’s Common Stock.

		·	There can be no assurance that the Company’s Common Stock will be listed on The NASDAQ Capital
Market, the NYSE MKT or any other national securities exchange.

		·	As of June 30, 2016, we had federal net operating loss carryforwards of $26,725,315, which begin
to expire in fiscal 2016.  Under Section 382 of the Internal Revenue Code of 1986, as amended, or the Code, changes in our
ownership may limit the amount of our net operating loss carryforwards that could be utilized annually to offset our future taxable
income, if any. This limitation would generally apply in the event of a cumulative change in ownership of our company of more than
50% within a three-year period. Any such limitation may significantly reduce our ability to utilize our net operating loss carryforwards
and tax credit carryforwards before they expire. Any such limitation, whether as the result of future offerings, prior private
placements, sales of our common stock by our existing stockholders or additional sales of our common stock by us in the future
(through the exercise of outstanding Warrants, or otherwise), could have a material adverse effect on our results of operations
in future years. We have not completed a study to assess whether an ownership change for purposes of Section 382 has occurred,
or whether there have been multiple ownership changes since our inception, due to the significant costs and complexities associated
with such study.

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