Document:

EX-4.31

 Exhibit 4.31 
  

 
 MPT OF NACOGDOCHES FCER, LLC, 

MPT OF MESA, LLC 
 MPT OF PORT
ARTHUR, LLC, 
 MPT OF WEST MONROE, LLC, 

MPT OF DALLAS, LLC 
 MPT RHM HOLDCO,

 MPT RHM SONNENWENDE, 
 MPT RHM
KLAUS, 
 MPT RHM VESALIUS, 
 MPT
RHM PARK, 
 MPT RHM FONTANA, 

MPT RHM HILLERSBACH 
 and 

MPT RHM CHRISTIAAN, 
 as Guarantors,

 MPT OPERATING PARTNERSHIP, L.P. 

and 
 MPT FINANCE CORPORATION, 

as Issuers, 
 MEDICAL PROPERTIES
TRUST, INC., 
 as Parent and a Guarantor, 

the other GUARANTORS named herein, 

as Guarantors, 
 and 

WILMINGTON TRUST, NATIONAL ASSOCIATION, 

as Trustee 
  

 
 THIRD
SUPPLEMENTAL INDENTURE 
 Dated as of December 20, 2013 

To 
 INDENTURE 

Dated as of October 10, 2013 

5.70% Senior Notes due 2020 
  

 

 THIRD SUPPLEMENTAL INDENTURE 

THIRD SUPPLEMENTAL INDENTURE (this “Third Supplemental Indenture”), dated as of
December 20, 2013, by and among MPT of Nacogdoches FCER, LLC, a Delaware limited liability company, MPT of Mesa, LLC, a Delaware limited liability company, MPT of Port Arthur, LLC, a Delaware limited liability company, MPT of West Monroe, LLC,
a Delaware limited liability company, MPT of Dallas, LLC, a Delaware limited liability company (the “Domestic Guarantors”), and MPT RHM Holdco, MPT RHM Sonnenwende, MPT RHM Klaus, MPT RHM Vesalius, MPT RHM Park, MPT RHM Fontana, MPT
RHM Hillersbach, MPT RHM Christiaan, each a société à responsabilité limitée incorporated and existing under the laws of the Grand Duchy of Luxembourg (the “Lux Guarantors” and together with
the Domestic Guarantors, the “New Guaranteeing Subsidiaries”), MPT Operating Partnership, L.P., a Delaware limited partnership (“Opco”), MPT Finance Corporation, a Delaware corporation (“Finco” and,
together with Opco, the “Issuers”), Medical Properties Trust, Inc., a Maryland corporation (the “Parent”), as Guarantor, each of the other Guarantors (as defined in the Indenture), as Guarantors, and Wilmington
Trust, National Association, existing under the laws of the United States of America, as Trustee (the “Trustee”). 

WITNESSETH 
 WHEREAS, the
Issuers and the Guarantors have heretofore executed and delivered an Indenture, dated as of October 10, 2013 (the “Base Indenture”), as supplemented by that certain First Supplemental Indenture, dated as of October 10,
2013 (the “First Supplemental Indenture”) and by that certain Second Supplemental Indenture, dated October 30, 2013 (the “Second Supplemental Indenture”, and together with the First Supplemental Indenture and
the Base Indenture, the “Indenture”), providing for the issuance by the Issuers of the 5.750% Senior Notes due 2020 (the “Notes”); 

WHEREAS, pursuant to Section 10.01(a)(4) of the Indenture, the Parent, the Issuers, the Guarantors and the Trustee, together, may
supplement the Indenture without notice to or the consent of any Holders or any other party to the Indenture in order to add Guarantees with respect to the Notes; 

WHEREAS, as of November 21, 2013, the Domestic Guarantors guaranteed the Credit Agreement, with the exception of MPT of Dallas, LLC, and
pursuant to Section 5.14(a) of the Indenture, the Domestic Guarantors are required to become Guarantors under the Indenture; 

WHEREAS, the Indenture requires that an entity that constitutes a Guarantor shall join the Issuers and the existing Guarantors in executing
and delivering to the Trustee a supplemental indenture pursuant to which such entity shall unconditionally Guarantee, on a joint and several basis, the full and prompt payment of the principal of, premium, if any, and interest in respect of the
Notes on a senior basis and all other obligations under the Indenture; 
 WHEREAS, the Lux Guarantors and MPT of Dallas, LLC wish to join
the Issuers and the existing Guarantors in executing and delivering to the Trustee a supplemental indenture pursuant to which the Lux Guarantors and MPT of Dallas, LLC shall unconditionally Guarantee,

 
on a joint and several basis, the full and prompt payment of the principal of, premium, if any, and interest in respect of the Notes on a senior basis and all other obligations under the
Indenture; and 
 WHEREAS, pursuant to Section 10.06 of the Indenture, the Trustee is authorized to execute and deliver this Third
Supplemental Indenture. 
 NOW, THEREFORE, in consideration of the foregoing and for other good and valuable consideration, the receipt of
which is hereby acknowledged, the Issuers, the Guarantors, the Trustee and the New Guaranteeing Subsidiaries mutually covenant and agree for the equal and ratable benefit of the Holders of the Notes as follows: 

1. CAPITALIZED TERMS. Capitalized terms used herein without definition shall have the meanings assigned to
them in the Indenture. The rules of interpretation set forth in the Indenture shall be applied here as if set forth in full herein. 
 2.
AGREEMENT TO GUARANTEE. The New Guaranteeing Subsidiaries hereby agree to provide unconditional Guarantees on the terms and subject to the conditions set forth in the Indenture including, but not limited
to, Article 11 thereof. 
 3. MISCELLANEOUS PROVISIONS. 

(a) The Trustee makes no undertaking or representation in respect of, and shall not be responsible in any manner whatsoever for and in respect
of, the validity or sufficiency of this Third Supplemental Indenture or the proper authorization or the due execution hereof by the Issuers or for or in respect of the recitals and statements contained herein, all of which recitals and statements
are made solely by the Issuers. 
 (b) On the date hereof, the Indenture shall be supplemented and amended in accordance herewith, and this
Third Supplemental Indenture shall form part of the Indenture for all purposes, and the Holder of every Note heretofore or hereafter authenticated and delivered under the Indenture shall be bound thereby. The Trustee accepts the trusts created by
the Indenture, as amended and supplemented by this Third Supplemental Indenture, and agrees to perform the same upon the terms and conditions of the Indenture, as amended and supplemented by this Third Supplemental Indenture. 

(c) This Third Supplemental Indenture shall be deemed to be incorporated in, and made a part of, the Indenture. The Indenture, as amended and
supplemented by this Third Supplemental Indenture, shall be read, taken and construed as one and the same instrument and all the provisions of the Indenture shall remain in full force and effect in accordance with the terms thereof and as amended
and supplemented by this Third Supplemental Indenture. 
 (d) THIS THIRD SUPPLEMENTAL INDENTURE SHALL BE GOVERNED BY, AND
CONSTRUED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW YORK. 

 (e) This Third Supplemental Indenture may be executed in any number of counterparts, each of
which so executed shall be deemed to be an original, but all such counterparts shall together constitute but one and the same instrument. 

 IN WITNESS WHEREOF, the parties hereto have caused this Third Supplemental Indenture to be duly
executed and attested, all as of the date first above written. 
  

											
	MPT OPERATING PARTNERSHIP, L.P., as Issuer
			
		 	By:	 	 MEDICAL PROPERTIES TRUST, LLC,

its general partner

				
		 		 	 By:
	 	MEDICAL PROPERTIES TRUST, INC., its sole member
					
		 		 		 	By:	 	 /s/ R. Steven Hamner

		 		 		 		 	Name:	 	R. Steven Hamner
		 		 		 		 	Title:	 	Executive Vice President and Chief Financial Officer

 
											
	
	 MPT FINANCE CORPORATION,
 as
Issuer

		
	By:	 	 /s/ R. Steven Hamner

		 	Name:	 	R. Steven Hamner
		 	Title:	 	President, Secretary and General Manager
	
	 MEDICAL PROPERTIES TRUST, INC.,
 as
Parent and a Guarantor

		
	By:	 	 /s/ R. Steven Hamner

		 	Name:	 	R. Steven Hamner
		 	Title:	 	Executive Vice President and Chief Financial Officer

 
											
	
	MEDICAL PROPERTIES TRUST, LLC
		
	By:	 	 MEDICAL PROPERTIES TRUST, INC.,
 its
sole member

		
	By:	 	 /s/ R. Steven Hamner

	Name:	 	R. Steven Hamner
	Title:	 	Executive Vice President and Chief Financial Officer

  

	
	 

  

THIRD SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

	
	MPT OF VICTORVILLE, LLC
	MPT OF BUCKS COUNTY, LLC
	MPT OF BLOOMINGTON, LLC
	MPT OF COVINGTON, LLC
	MPT OF DENHAM SPRINGS, LLC
	MPT OF REDDING, LLC
	MPT OF CHINO, LLC
	MPT OF DALLAS LTACH, LLC
	MPT OF PORTLAND, LLC
	MPT OF WARM SPRINGS, LLC
	MPT OF VICTORIA, LLC
	MPT OF LULING, LLC
	MPT OF WEST ANAHEIM, LLC
	MPT OF LA PALMA, LLC
	MPT OF PARADISE VALLEY, LLC
	MPT OF SOUTHERN CALIFORNIA, LLC
	MPT OF TWELVE OAKS, LLC
	MPT OF SHASTA, LLC
	MPT OF BOSSIER CITY, LLC
	MPT OF WEST VALLEY CITY, LLC
	MPT OF IDAHO FALLS, LLC
	MPT OF POPLAR BLUFF, LLC
	MPT OF BENNETTSVILLE, LLC
	MPT OF DETROIT, LLC
	MPT OF BRISTOL, LLC
	MPT OF NEWINGTON, LLC
	MPT OF ENFIELD, LLC
	MPT OF PETERSBURG, LLC
	MPT OF GARDEN GROVE HOSPITAL, LLC
	MPT OF GARDEN GROVE MOB, LLC
	MPT OF SAN DIMAS HOSPITAL, LLC
	MPT OF SAN DIMAS MOB, LLC
	MPT OF CHERAW, LLC
	MPT OF FT. LAUDERDALE, LLC.
	MPT OF PROVIDENCE, LLC
	MPT OF SPRINGFIELD, LLC
	MPT OF WARWICK, LLC
	MPT OF RICHARDSON, LLC
	MPT OF ROUND ROCK, LLC
	MPT OF SHENANDOAH, LLC
	MPT OF HILLSBORO, LLC
	MPT OF FLORENCE, LLC
	MPT OF CLEAR LAKE, LLC
	MPT OF TOMBALL, LLC
	MPT OF GILBERT, LLC
	MPT OF CORINTH, LLC
	MPT OF BAYONNE, LLC
	MPT OF ALVARADO, LLC

  

THIRD SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

 
	
	MPT OF DESOTO, LLC
	 MPT OF HAUSMAN, LLC
 MPT OF HOBOKEN HOSPITAL,
LLC
 MPT OF HOBOKEN REAL ESTATE, LLC
 MPT OF OVERLOOK PARKWAY,
LLC
 MPT OF NEW BRAUNFELS, LLC
 MPT OF WESTOVER HILLS,
LLC

	MPT OF WICHITA, LLC
	MPT OF BILLINGS, LLC
	MPT OF BOISE, LLC
	MPT OF BROWNSVILLE, LLC
	MPT OF CASPER, LLC
	MPT OF COMAL COUNTY, LLC
	MPT OF GREENWOOD, LLC
	MPT OF JOHNSTOWN, LLC
	MPT OF LAREDO, LLC
	MPT OF LAS CRUCES, LLC
	MPT OF MESQUITE, LLC
	MPT OF POST FALLS, LLC
	MPT OF PRESCOTT VALLEY, LLC
	MPT OF PROVO, LLC
	MPT OF NORTH CYPRESS, LLC
	MPT OF LAFAYETTE, LLC
	MPT OF INGLEWOOD LLC
	MPT OF RENO, LLC
	MPT OF ROXBOROUGH, LLC
	MPT OF ALTOONA, LLC
	MPT OF HAMMOND, LLC
	MPT OF SPARTANBURG, LLC
	MPT OF WYANDOTTE COUNTY, LLC
	MPT OF LEAVENWORTH, LLC
	MPT OF CORPUS CHRISTI, LLC
	MPT OF BRODIE FCER, LLC
	MPT OF LITTLE ELM FCER, LLC
	MPT OF OGDEN, LLC
	MPT OF NACOGDOCHES FCER, LLC
	MPT OF MESA, LLC
	MPT OF PORT ARTHUR, LLC

  

THIRD SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

 
											
	 MPT OF WEST MONROE, LLC
 MPT OF
DALLAS, LLC

		
	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

sole member of each of the above entities

			
		 	By:	 	 MEDICAL PROPERTIES TRUST, LLC,
 its
general partner

				
		 		 	By:	 	 MEDICAL PROPERTIES TRUST, INC.,

its sole member

					
		 		 		 	By:	 	 /s/ R. Steven Hamner

		 		 		 		 	Name:	 	R. Steven Hamner
		 		 		 		 	Title:	 	Executive Vice President and Chief Financial Officer
	
	MPT OF BUCKS COUNTY, L.P.
	By:	 	MPT OF BUCKS COUNTY, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

				
		 		 	By:	 	 MEDICAL PROPERTIES TRUST, LLC,

its general partner

					
		 		 		 	By:	 	 MEDICAL PROPERTIES TRUST, INC.,

its sole member

	
	MPT OF DALLAS LTACH, L.P.
	By:	 	MPT OF DALLAS LTACH, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

				
		 		 	By:	 	 MEDICAL PROPERTIES TRUST, LLC,

its general partner

					
		 		 		 	By:	 	 MEDICAL PROPERTIES TRUST, INC.,

its sole member

  

THIRD SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

 
											
	MPT OF WARM SPRINGS, L.P.
	By:	 	MPT OF WARM SPRINGS, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

					
		 		 	By:	 		 	 MEDICAL PROPERTIES TRUST, LLC,
 its
general partner

						
		 		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC.,
		 		 		 		 		 	its sole member
	
	MPT OF VICTORIA, L.P.
	By:	 	MPT OF VICTORIA, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

					
		 		 	By:	 		 	 MEDICAL PROPERTIES TRUST, LLC,
 its
general partner

						
		 		 		 		 	By:	 	 MEDICAL PROPERTIES TRUST, INC.,

its sole member

	
	MPT OF LULING, L.P.
	By:	 	MPT OF LULING, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

					
		 		 	By:	 		 	 MEDICAL PROPERTIES TRUST, LLC,
 its
general partner

						
		 		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC.,
		 		 		 		 		 	its sole member

  

THIRD SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

 
											
	MPT OF WEST ANAHEIM, L.P.
	By:	 	MPT OF WEST ANAHEIM, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

				
		 		 	By:	 	 MEDICAL PROPERTIES TRUST, LLC,
 its
general partner

						
		 		 		 		 	By:	 	 MEDICAL PROPERTIES TRUST, INC.,

its sole member

	
	MPT OF LA PALMA, L.P.
	By:	 	MPT OF LA PALMA, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

				
		 		 	By:	 	 MEDICAL PROPERTIES TRUST, LLC,
 its
general partner

						
		 		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC.,
		 		 		 		 		 	its sole member

  

THIRD SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

 
											
	MPT OF PARADISE VALLEY, L.P.
	By:	 	MPT OF PARADISE VALLEY, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

					
		 		 	By:	 		 	 MEDICAL PROPERTIES TRUST, LLC,
 its
general partner

						
		 		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC.,
		 		 		 		 		 	its sole member
	
	MPT OF SOUTHERN CALIFORNIA, L.P.
	By:	 	MPT OF SOUTHERN CALIFORNIA, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

					
		 		 	By:	 		 	 MEDICAL PROPERTIES TRUST, LLC,
 its
general partner

						
		 		 		 		 	By:	 	 MEDICAL PROPERTIES TRUST, INC.,

its sole member

	
	MPT OF TWELVE OAKS, L.P.
	By:	 	MPT OF TWELVE OAKS, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

					
		 		 	By:	 		 	 MEDICAL PROPERTIES TRUST, LLC,
 its
general partner

						
		 		 		 		 	By:	 	 MEDICAL PROPERTIES TRUST, INC.,

its sole member

  

THIRD SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

 
									
	MPT OF SHASTA, L.P.
	By:	 	MPT OF SHASTA, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

				
		 		 	By:	 	 MEDICAL PROPERTIES TRUST, LLC,

its general partner

					
		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC.,
		 		 		 		 	its sole member
	
	 MPT OF GARDEN GROVE HOSPITAL, L.P.

	By:	 	MPT OF GARDEN GROVE HOSPITAL, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

				
		 		 	By:	 	 MEDICAL PROPERTIES TRUST, LLC,

its general partner

					
		 		 		 	By:	 	 MEDICAL PROPERTIES TRUST, INC.,

its sole member

	
	MPT OF GARDEN GROVE MOB, L.P.
	By:	 	MPT OF GARDEN GROVE MOB, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

				
		 		 	By:	 	 MEDICAL PROPERTIES TRUST, LLC,

its general partner

					
		 		 		 	By:	 	 MEDICAL PROPERTIES TRUST, INC.,
 its sole
member

  

THIRD SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

 
											
	MPT OF SAN DIMAS HOSPITAL, L.P.
	By:	 	MPT OF SAN DIMAS HOSPITAL, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

					
		 		 	By:	 		 	 MEDICAL PROPERTIES TRUST, LLC,
 its
general partner

						
		 		 		 		 	By:	 	 MEDICAL PROPERTIES TRUST, INC.,
 its sole
member

	
	MPT OF SAN DIMAS MOB, L.P.
	By:	 	MPT OF SAN DIMAS MOB, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

					
		 		 	By:	 		 	 MEDICAL PROPERTIES TRUST, LLC,
 its
general partner

						
		 		 		 		 	By:	 	 MEDICAL PROPERTIES TRUST, INC.,

its sole member

	
	MPT OF RICHARDSON, L.P.
	By:	 	MPT OF RICHARDSON, LLC, its general partner
			
		 	By:	 	 MPT OPERATING PARTNERSHIP, L.P.,

its sole member

					
		 		 	By:	 		 	 MEDICAL PROPERTIES TRUST, LLC,
 its
general partner

						
		 		 		 		 	By:	 	 MEDICAL PROPERTIES TRUST, INC.,
 its sole
member

  

SECOND SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

 
									
	MPT OF ROUND ROCK, L.P.
	By:	 	MPT OF ROUND ROCK, LLC, its general partner
			
		 	By:	 	MPT OPERATING PARTNERSHIP, L.P.,
		 		 	its sole member
				
		 		 	By:	 	MEDICAL PROPERTIES TRUST, LLC,
		 		 		 	its general partner
					
		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC., its sole member
	
	MPT OF SHENANDOAH, L.P.
	By:	 	MPT OF SHENANDOAH, LLC, its general partner
			
		 	By:	 	MPT OPERATING PARTNERSHIP, L.P.,
		 		 	its sole member
				
		 		 	By:	 	MEDICAL PROPERTIES TRUST, LLC,
		 		 		 	its general partner
					
		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC., its sole member
	
	MPT OF HILLSBORO, L.P.
	By:	 	MPT OF HILLSBORO, LLC, its general partner
			
		 	By:	 	MPT OPERATING PARTNERSHIP, L.P.,
		 		 	its sole member
				
		 		 	By:	 	MEDICAL PROPERTIES TRUST, LLC,
		 		 		 	its general partner
					
		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC., its sole member

  

SECOND SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

 
									
	MPT OF CLEAR LAKE, L.P.
	By:	 	MPT OF CLEAR LAKE, LLC, its general partner
			
		 	By:	 	MPT OPERATING PARTNERSHIP, L.P.,
		 		 	its sole member
				
		 		 	By:	 	MEDICAL PROPERTIES TRUST, LLC,
		 		 		 	its general partner
					
		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC., its sole member
	
	MPT OF TOMBALL, L.P.
	By:	 	MPT OF TOMBALL, LLC, its general partner
			
		 	By:	 	MPT OPERATING PARTNERSHIP, L.P.,
		 		 	its sole member
				
		 		 	By:	 	MEDICAL PROPERTIES TRUST, LLC,
		 		 		 	its general partner
					
		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC., its sole member
	
	MPT OF CORINTH, L.P.
	By:	 	MPT OF CORINTH, LLC, its general partner
			
		 	By:	 	MPT OPERATING PARTNERSHIP, L.P.,
		 		 	its sole member
				
		 		 	By:	 	MEDICAL PROPERTIES TRUST, LLC,
		 		 		 	its general partner
					
		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC., its sole member

  

SECOND SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

 
									
	MPT OF ALVARADO, L.P.
	By:	 	MPT OF ALVARADO, LLC, its general partner
			
		 	By:	 	MPT OPERATING PARTNERSHIP, L.P.,
		 		 	its sole member
				
		 		 	By:	 	MEDICAL PROPERTIES TRUST, LLC,
		 		 		 	its general partner
					
		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC., its sole member
	
	MPT OF DESOTO, L.P.
	By:	 	MPT OF DESOTO, LLC, its general partner
			
		 	By:	 	MPT OPERATING PARTNERSHIP, L.P.,
		 		 	its sole member
				
		 		 	By:	 	MEDICAL PROPERTIES TRUST, LLC,
		 		 		 	its general partner
					
		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC., its sole member
	
	MPT OF MOUNTAIN VIEW LLC
	By:	 	MPT OF IDAHO FALLS, LLC, its sole member
			
		 	By:	 	MPT OPERATING PARTNERSHIP, L.P.,
		 		 	its sole member
				
		 		 	By:	 	MEDICAL PROPERTIES TRUST, LLC,
		 		 		 	its general partner
					
		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC., its sole member

  

SECOND SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

 
									
	WICHITA HEALTH ASSOCIATES LIMITED PARTNERSHIP
	By:	 	MPT OF WICHITA, LLC, its general partner
			
		 	By:	 	MPT OPERATING PARTNERSHIP, L.P.,
		 		 	its sole member
				
		 		 	By:	 	MEDICAL PROPERTIES TRUST, LLC,
		 		 		 	its general partner
					
		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC., its sole member
	
	MPT OF NORTH CYPRESS, L.P.
	By:	 	MPT OF NORTH CYPRESS, LLC, its general partner
			
		 	By:	 	MPT OPERATING PARTNERSHIP, L.P.,
		 		 	its sole member
				
		 		 	By:	 	MEDICAL PROPERTIES TRUST, LLC,
		 		 		 	its general partner
					
		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC., its sole member
	
	MPT OF INGLEWOOD, L.P.
	By:	 	MPT OF INGLEWOOD, LLC, its general partner
			
		 	By:	 	MPT OPERATING PARTNERSHIP, L.P.,
		 		 	its sole member
				
		 		 	By:	 	MEDICAL PROPERTIES TRUST, LLC,
		 		 		 	its general partner
					
		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC., its sole member

  

SECOND SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

 
									
	MPT OF ROXBOROUGH, L.P.
	By:	 	MPT OF ROXBOROUGH, LLC, its general partner
			
		 	By:	 	MPT OPERATING PARTNERSHIP, L.P.,
		 		 	its sole member
				
		 		 	By:	 	MEDICAL PROPERTIES TRUST, LLC,
		 		 		 	its general partner
					
		 		 		 	By:	 	MEDICAL PROPERTIES TRUST, INC., its sole member
	
	MEDICAL PROPERTIES TRUST, LLC
	By:	 	MEDICAL PROPERTIES TRUST, INC., its sole member
			
		 	By:	 	 /s/ R. Steven Hamner

		 		 	Name:	 	R. Steven Hamner
		 		 	Title:	 	Executive Vice President and Chief Financial Officer

  

									
	 /s/ Leanne McWilliams
	 		 	 /s/ James Kevin Hanna

	MPT RHM Holdco	 		 	MPT RHM Holdco
	By:	 	Leanne McWilliams	 		 	By:	 	James Kevin Hanna
	Title:	 	Manager	 		 	Title:	 	Manager
			
	 /s/ Leanne McWilliams
	 		 	 /s/ James Kevin Hanna

	MPT RHM Sonnenwende	 		 	MPT RHM Sonnenwende
	By:	 	Leanne McWilliams	 		 	By:	 	James Kevin Hanna
	Title:	 	Manager	 		 	Title:	 	Manager
			
	 /s/ Leanne McWilliams
	 		 	 /s/ James Kevin Hanna

	MPT RHM Klaus	 		 	MPT RHM Klaus
	By:	 	Leanne McWilliams	 		 	By:	 	James Kevin Hanna
	Title:	 	Manager	 		 	Title:	 	Manager
			
	 /s/ Leanne McWilliams
	 		 	 /s/ James Kevin Hanna

	MPT RHM Vesalius	 		 	MPT RHM Vesalius
	By:	 	Leanne McWilliams	 		 	By:	 	James Kevin Hanna
	Title:	 	Manager	 		 	Title:	 	Manager
			
	 /s/ Leanne McWilliams
	 		 	 /s/ James Kevin Hanna

	MPT RHM Park	 		 	MPT RHM Park
	By:	 	Leanne McWilliams	 		 	By:	 	James Kevin Hanna
	Title:	 	Manager	 		 	Title:	 	Manager

  

SECOND SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

									
			
	 /s/ Leanne McWilliams
	 		 	 /s/ James Kevin Hanna

	MPT RHM Fontana	 		 	MPT RHM Fontana
	By:	 	Leanne McWilliams	 		 	By:	 	James Kevin Hanna
	Title:	 	Manager	 		 	Title:	 	Manager
			
	 /s/ Leanne McWilliams
	 		 	 /s/ James Kevin Hanna

	MPT RHM Hillersbach	 		 	MPT RHM Hillersbach
	By:	 	Leanne McWilliams	 		 	By:	 	James Kevin Hanna
	Title:	 	Manager	 		 	Title:	 	Manager
			
	 /s/ Leanne McWilliams
	 		 	 /s/ James Kevin Hanna

	MPT RHM Christiaan	 		 	MPT RHM Christiaan
	By:	 	Leanne McWilliams	 		 	By:	 	James Kevin Hanna
	Title:	 	Manager	 		 	Title:	 	Manager

  

SECOND SUPPLEMENTAL INDENTURE SIGNATURE PAGE 

 
					
	WILMINGTON TRUST, NATIONAL ASSOCIATION, as Trustee,
		
	By:	 	 /s/ Michael H. Wass

		 	Name:	 	Michael H. Wass
		 	Title:	 	Assistant Vice President

  

SECOND SUPPLEMENTAL INDENTURE SIGNATURE PAGEEX-10.2(e)

 Exhibit 10.2E 

VARIETAL DISTRIBUTION HOLDINGS, LLC 

2007 SECURITIES PURCHASE PLAN 

1. Purpose of Plan. This 2007 Securities Purchase Plan (the “Plan”) of Varietal Distribution Holdings, LLC, a Delaware
limited liability company (the “Company”), adopted by the Board of Managers of the Company on June 29, 2007, for employees, managers, consultants and advisers of the Company and its Subsidiaries, is intended to advance the best
interests of the Company and its Subsidiaries by providing those persons who have a substantial responsibility for their management and growth with additional incentives by allowing such persons to acquire an equity interest in the Company and
thereby encouraging them to contribute to the success of the Company and its Subsidiaries and, in the case of employees, to remain in their employ. The availability and offering of Common Units and Preferred Units under the Plan also is intended to
increase the Company’s and its Subsidiaries’ ability to attract and retain individuals of exceptional managerial talent upon whom, in large measure, the sustained progress, growth, and profitability of the Company and its Subsidiaries
depends. The Plan is intended to be a compensatory benefit plan within the meaning of Rule 701 of the Securities Act and, unless and until the Common Units and Preferred Units are publicly traded, the issuance of Common Units and Preferred Units
pursuant to the Plan is intended to qualify for the exemption from registration under the Securities Act provided by Rule 701; provided that the foregoing shall not require the Company to rely on Rule 701 for any issuance pursuant to this
Plan to the extent that another exemption from registration under the Securities Act is available for such issuance. 
 2.
Definitions. Capitalized terms used but not otherwise defined herein shall have the meanings set forth below: 

“Affiliate” of any particular Person means any other Person controlling, controlled by, or under common control with such
particular Person, where “control” means the possession, directly or indirectly, of the power to direct the management and policies of a Person whether through the ownership of voting securities, by contract, or otherwise. 

“Board” means the Board of Managers of the Company or any successor governing body thereto. 

“Common Units” means “Class A Common Units”, as such term is defined in the Limited Liability Company Agreement.

 “Committee” means the committee of the Board which may be designated by the Board to administer the Plan. The Committee
shall be composed of two or more managers as appointed from time to time to serve by the Board. 
 “Limited Liability Company
Agreement” means “LLC Agreement” means the Limited Liability Company Agreement of the Company, dated on or about the date hereof among the parties from time to time party thereto, as amended from time to time pursuant to
its terms. 

  
 - 1 - 

 “Participants” means present and future employees, managers, consultants or
advisers of the Company or its Subsidiaries, as such persons may be selected in the sole discretion of the Committee. 

“Person” means an individual, a partnership, a limited liability company, a corporation, an association, a joint stock
company, a trust, a joint venture, an unincorporated organization, an investment fund, any other business entity and a governmental entity or any department, agency or political subdivision thereof. 

“Preferred Units” means the “Class A Preferred Units”, as such term is defined in the Limited Liability Company
Agreement. 
 “Subsidiary” means, with respect to any Person, any corporation, limited liability company, partnership,
association, or business entity of which (i) if a corporation, a majority of the total voting power of shares of stock entitled (without regard to the occurrence of any contingency) to vote in the election of directors, managers, or trustees
thereof is at the time owned or controlled, directly or indirectly, by that Person or one or more of the other Subsidiaries of that Person or a combination thereof, or (ii) if a limited liability company, partnership, association, or other
business entity (other than a corporation), a majority of partnership or other similar ownership interest thereof is at the time owned or controlled, directly or indirectly, by that Person or one or more Subsidiaries of that Person or a combination
thereof. For purposes hereof, a Person or Persons shall be deemed to have a majority ownership interest in a limited liability company, partnership, association, or other business entity (other than a corporation) if such Person or Persons shall be
allocated a majority of limited liability company, partnership, association, or other business entity gains or losses or shall be or control any managing director or general partner of such limited liability company, partnership, association, or
other business entity. 
 “Securityholders Agreement” means the Securityholders Agreement, dated on or about the date of
the adoption of this Plan, among the Company and holders of the Units signatories thereto, as the same may be amended, supplemented or otherwise modified from time to time. 

“Units” has the meaning given to such term in the Limited Liability Company Agreement. 

3. Grant or Sale of Units. The Committee shall have the power and authority to grant without consideration or to sell to any
Participant any Units at any time prior to the termination of this Plan in such quantity, at such price, on such terms and subject to such conditions that are consistent with this Plan and established by the Committee. Units granted or sold under
this Plan shall be subject to such terms and evidenced by agreements as shall be determined from time to time by the Committee (each a “Management Unit Purchase Agreement”). Participants receiving grants or purchasing Units pursuant
to this Plan shall be required, as a condition to such grant or purchase, to become a party to the Limited Liability Company Agreement, the Securityholders Agreement and any other agreement or arrangement determined by the Committee. 

4. Administration of the Plan. The Plan shall be administered by the Committee; provided that if for any reason the Committee
shall not have been appointed by the Board, all authority and duties of the Committee under the Plan shall be vested in and exercised by the Board. 

  
 - 2 - 

 
Subject to the limitations of this Plan, the Committee shall have the sole and complete authority to: (i) select Participants, (ii) grant or sell Units to Participants on such terms and
in such amounts as it shall determine, (iii) impose such limitations, restrictions and conditions upon such Units as it shall deem appropriate, (iv) interpret this Plan and, as applied to Participants and their permitted transferees, the
LLC Agreement, the Securityholders Agreement and the Management Unit Purchase Agreement (collectively with the Plan, the “Equity Agreements”) and adopt, amend and rescind administrative guidelines and other rules and regulations
relating to the Equity Agreements as applied to Participants and their permitted transferees, (v) correct any defect or omission or reconcile any inconsistency in the Equity Agreements as applied to Participants and their permitted transferees
and (vi) make all other determinations and take all other actions necessary or advisable for the implementation and administration of the Equity Agreements as applied to Participants and their permitted transferees. Each action of the Committee
or the Board shall be binding on all Participants. 
 5. Taxes. The Company shall be entitled, if necessary or desirable, to withhold
(or secure payment from any Participant in lieu of withholding) the amount of any withholding or other tax due from the Company with respect to any amount payable and/or Units issuable under this Plan, and the Company may defer such payment or
issuance unless indemnified to its satisfaction. 
 6. Rights of Participants. Nothing in this Plan or in any Equity Agreement shall
interfere with or limit in any way the right of the Company or any Subsidiary to terminate any Participant’s employment at any time (with or without cause), nor confer upon any Participant any right to continue in the employ of the Company or
any Subsidiaries or Affiliates for any period of time or to continue his or her present (or any other) rate of compensation. No person shall have a right to be selected as a Participant or, having been so selected, to be selected again as a
Participant. 
 7. Certain Adjustments. The number of Units issued under the Plan to each Participant shall be proportionately
adjusted in the case of a Unit split, reverse Unit split, Unit dividend, recapitalization, combination, reclassification or other distribution in respect of the Units without the receipt of consideration by the Company. 

8. Amendment, Suspension, and Termination of Plan. The Board or the Committee may suspend or terminate the Plan or any portion thereof
at any time and may amend it from time to time in such respects as the Board or the Committee may deem advisable; provided that no such amendment shall be made without the approval of the Board to the extent such approval is required by law,
agreement or the rules of any exchange upon which the Units are listed, and no such amendment, suspension, or termination shall impair the rights of Participants under outstanding Management Unit Purchase Agreements without the consent of the
Participants affected thereby, except to the extent provided for in any such Management Unit Purchase Agreement. The Plan shall terminate on the tenth anniversary of the date the Plan has been adopted by the Board and no Units shall be issued
hereunder after such date. 
 9. Indemnification. In addition to such other rights of indemnification as they may have as members of
the Board or the Committee, the members of the Board and the Committee shall be indemnified by the Company against all costs and expenses reasonably incurred by them in connection with any action, suit, or proceeding to which they or any of them may
be party by reason of any action taken or failure to act under or in connection with the Plan or any Units issued 

  
 - 3 - 

 
hereunder, and against all amounts paid by them in settlement thereof (provided such settlement is approved by independent legal counsel selected by the Company) or paid by them in satisfaction
of a judgment in any such action, suit or proceeding; provided that any such Board or Committee member shall be entitled to the indemnification rights set forth in this Section 9 only if such Board or Committee member has acted in
good faith and in a manner that such Board or Committee member reasonably believed to be in, or not opposed to, the best interests of the Company and, with respect to any criminal action or proceeding, had no reasonable cause to believe that such
conduct was unlawful, and further provided that upon the institution of any such action, suit, or proceeding a Board or Committee member shall give the Company written notice thereof and an opportunity, at the Company’s own expense, to handle
and defend the same before such Board or Committee member undertakes to handle and defend such action, suit or proceeding on his own behalf. 

10. Shareholder Approval. The Plan shall be duly approved by a majority of the outstanding Class A Common Units of the Company
entitled to vote within 12 months after the Plan has been adopted by the Board. 
 Adopted by the Board of Managers of the Company, on June 29, 2007.

 *    *    *    *    * 

  
 - 4 - 

 APPENDIX A 

TO THE 
 VARIETAL
DISTRIBUTION HOLDINGS, LLC 
 2007 SECURITIES PURCHASE PLAN 

1. General 
 (a) Amendment of and
Relation to the Plan. This Appendix A (this “Appendix”) is an appendix to the Varietal Distribution Holdings, LLC 2007 Securities Purchase Plan (as amended or modified from time to time in accordance with its terms, the
“Plan”). Any capitalized term not specifically defined in this Appendix shall be construed according to the interpretation given to it in the Plan. The provisions specified hereunder shall form an integral part of the Plan and is to
be read as part of and a continuation of the Plan. Upon adoption of this Appendix by the Board, the Plan is hereby amended to add this Appendix to it and to replace the definition of “Common Units” in Section 2 thereof with the
following definition: ““Common Units” means “Class A Common Units,” as such term is defined in the Limited Liability Company Agreement and “Class B Common Units,” as such term is defined in the Limited
Liability Company Agreement.” For purposes of the Plan, Incentive Unit Grant Agreements issued subject to the Plan shall constitute Management Unit Purchase Agreements thereunder. 

(b) Limited Application. The terms of this Appendix shall apply only to a Management Unit Purchase Agreement that expressly
contemplates that the Common Units issued thereunder are subject to this Appendix. 
 (c) Maximum Units. Unless otherwise determined
by the Board, the maximum number of Common Units that may be issued pursuant to Management Unit Purchase Agreements to which this Appendix applies is 206,000. Common Units issued subject to this Appendix are referred to herein as “Incentive
Units.” 
 2. Vesting 
 (a)
Determination of EBITDA. Prior to or promptly following the filing with the Securities and Exchange Commission of the annual audited financial statements of VWR for a Measurement Period, the Board or Committee will determine the Adjusted
EBITDA Amount for such Measurement Period based on such audited financial statements and the vesting, if any, of Incentive Units as of such date of determination. The date that the Board or the Committee determines the Adjusted EBITDA Amount for
such Measurement Period and vesting for such Measurement Period is referred to herein as the “Determination Date.” 
 (b)
Incentive Units. For purposes of calculating the vesting of the Incentive Units (as defined in the applicable Management Unit Purchase Agreement), 60% of the Incentive Units shall be designated as “Group 1 Securities” and 40%
of the Incentive Units shall be designated as “Group 2 Securities.” 

  
 - 5 - 

 (c) Performance Vesting. The Incentive Units shall become vested, but only as long as a
Participant remains employed by either the Company, VWR or any of their respective Subsidiaries as of the date such vesting would otherwise occur, as follows: 

(i) Group 1 Securities. If upon a Determination Date the Adjusted EBITDA Amount for the applicable Measurement Period
equals or exceeds the Minimum EBITDA Amount, all of the Group 1 Securities shall vest. 
 (ii) Group 2 Securities. If
upon a Determination Date the Adjusted EBITDA Amount for the applicable Measurement Period exceeds the Minimum EBITDA Amount, a portion of the Group 2 Securities shall vest, on a straight line basis in an amount calculated pursuant to the following
formula: 
 The result of (A) the product of 
  

							
		 	Number of Group 2 Securities	  	X	  	
Adjusted EBITDA Amount – Minimum EBITDA Amount

	 	  	  	Maximum EBITDA Amount – Minimum EBITDA Amount

 minus (B) the number of Group 2 Securities that vested on a prior Determination Date, if any. 

(d) Automatic Vesting in Connection with a Sale of the Company. Notwithstanding anything contained in Section 2(c) of this
Appendix to the contrary, all of the Group 1 Securities and the Group 2 Securities shall automatically vest upon a Sale of the Company (as defined in the applicable Management Unit Purchase Agreement). 

(e) Vesting Limits. Notwithstanding anything contained in Section 2(c) or (d) of this Appendix to the contrary, in
the event that all or a portion of the Incentive Units have not vested on or prior to the earlier of (i) the Determination Date for the Measurement Period ending December 31, 2014 and (ii) the date on which Executive is no longer
employed by the Company, VWR or any of their respective Subsidiaries, such unvested Incentive Units shall remain unvested and no unvested Incentive Units shall vest thereafter. Further, in no event shall any Common Unit vest more than once. 

3. Definitions 
 (a) “Adjusted
EBITDA Amount” means, with respect to a Measurement Period, VWR and its Subsidiaries’ earnings before net interest expense, income taxes, depreciation, amortization and fees pursuant to the Management Services Agreement (as defined in
the LLC Agreement), as it may be amended from time to time, in each case, for such Measurement Period, determined on a consolidated basis based upon the annual financial statements for VWR for the applicable Measurement Period filed with the
Securities and Exchange Commission, as adjusted to reflect (w) the adjustments reflected in the description of “Adjusted EBITDA” contained in VWR’s Current Report on Form 8-K filed in connection with management’s
teleconference to discuss the annual financial results for such Measurement Period, (x) constant currency translation exchange rates as reflected in VWR International, LLC’s 2011 Internal Operating Plan (y) for any business acquired
after January 1, 2012, a constant currency translation exchange rate equal to the applicable Dollar to foreign currency exchange rate in effect on the closing date of such acquisition, and (z) for the Measurement

  
 - 6 - 

 
Period ending December 31, 2014, a pro forma adjustment for any business acquired in such Measurement Period to reflect the projected full year Adjusted EBITDA Amount as if such acquisition
had occurred on January 1, 2014. Adjusted EBITDA Amount shall be determined by the Board. 
 (b) “Maximum EBITDA
Amount” means $558 million. 
 (c) “Measurement Period” means each of the following three periods: (i) the
fiscal year ending December 31, 2012, (ii) the fiscal year ending December 31, 2013 and (iii) the fiscal year ending December 31, 2014. 

(d) “Minimum EBITDA Amount” means $500 million. 

(e) “Requisite Participants” means the Participants that hold a majority of the outstanding Common Units that were initially
subject to vesting under this Appendix. 
 (f) “Trigger Date” a Trigger Date shall have occurred as of the Determination
Date for the Measurement Period ending December 31, 2014 if after giving effect to any vesting that occurs on such date any of the Incentive Units remain unvested. 

(g) “VWR” means VWR Funding, Inc., a Delaware corporation. 

4. Miscellaneous 
 (a) Conflicts.
The Plan and this Appendix are complementary to each other and shall be deemed as one. In the event of any conflict, whether explicit or implied, between (a) the provisions of this Appendix and the Plan, (b) the provisions of a Management
Unit Purchase Agreement (that expressly refers to this Appendix) and the Plan, or (c) provisions of a Management Unit Purchase Agreement (that expressly refers to this Appendix) and this Appendix, in each case, the Committee shall have the
power to resolve such conflict and to determine which provisions shall prevail. 
 (b) Amendments. Notwithstanding anything contained
in the Plan or in any Management Unit Purchase Agreement to the contrary, the Board or the Committee may amend or modify this Appendix from time to time as the Board or the Committee may deem advisable; provided that no such amendment or
modification shall be made without the approval of the Board to the extent such approval is required by law, agreement or the rules of any exchange upon which the Units are listed, and no such amendment or modification shall impair the rights of
Participants under outstanding Management Unit Purchase Agreements that expressly refer to this Appendix without the consent or approval of the Requisite Participants. 

*    *    *    *    * 

  
 - 7 - 

 APPENDIX B 

TO THE 
 VARIETAL
DISTRIBUTION HOLDINGS, LLC 
 2007 SECURITIES PURCHASE PLAN 

1. General 
 (a) Amendment of and
Relation to the Plan. This Appendix B (this “Appendix”) is an appendix to the Varietal Distribution Holdings, LLC 2007 Securities Purchase Plan (as amended or modified from time to time in accordance with its terms, the
“Plan”). Any capitalized term not specifically defined in this Appendix shall be construed according to the interpretation given to it in the Plan. The provisions specified hereunder shall form an integral part of the Plan and is to
be read as part of and a continuation of the Plan. For purposes of the Plan, Incentive Unit Grant Agreements issued subject to the Plan shall constitute Management Unit Purchase Agreements thereunder. 

(b) Limited Application. The terms of this Appendix shall apply only to a Management Unit Purchase Agreement that expressly
contemplates that the Common Units issued thereunder are subject to this Appendix. 
 (c) Maximum Units. Unless otherwise determined
by the Board, the maximum number of Class B Common Units that may be issued pursuant to Management Unit Purchase Agreements to which this Appendix applies is 125,000. Class B Common Units issued subject to this Appendix are referred to herein as
“Incentive Units.” 
 2. Vesting 

(a) Time Vesting. Except as otherwise provided in this Section 2, the Incentive Units granted to a Participant pursuant to
an Incentive Unit Grant Agreement shall become vested on a daily, straight-line basis from the Issuance Date through the fourth anniversary of the Issuance Date such that 100% of the Incentive Units for such Participant will have vested as of the
fourth anniversary of the Issuance Date, but only as long as such Participant remains employed by the Company, VWR or any of their respective Subsidiaries. 

(b) Automatic Vesting in Connection with a Sale of the Company. Notwithstanding anything contained in Section 2(a) of this
Appendix to the contrary, all of the outstanding and not forfeited Incentive Units granted to a Participant pursuant to an Incentive Unit Grant Agreement subject to this Appendix with respect to a Participant shall automatically vest for such
Participant upon a Sale of the Company (as defined in the applicable Management Unit Purchase Agreement). 
 (c) Vesting upon an IPO.
Upon the occurrence of a Public Offering or Subsidiary Public Offering (the “IPO”), all Incentive Units granted to a Participant pursuant to an Incentive Unit Grant Agreement which were scheduled to vest pursuant to
Section 2(a) above during the one-year period following the date of the IPO will instead vest as of the 

  
 - 8 - 

 
consummation of the IPO, provided that the Participant is employed by the Company, VWR or any of their respective Subsidiaries as of the occurrence of the IPO. All remaining unvested Incentive
Units granted to a Participant pursuant to an Incentive Unit Grant Agreement will continue to vest on a daily, straight-line basis from the Closing Date through the third anniversary of the Closing Date such that 100% of the Incentive Units for such
Participant will have vested as of the third anniversary of the Closing Date, but only as long as such Participant remains employed by the Company, VWR or any of their respective Subsidiaries. 

(d) Vesting Limits. Notwithstanding anything contained in Sections 2(a), (b) or (c) of this Appendix to
the contrary, in the event that all or a portion of the Incentive Units granted to such Participant pursuant to an Incentive Unit Grant Agreement have not vested on or prior to the date on which a Participant is no longer employed by the Company,
VWR or any of their respective Subsidiaries, such unvested Incentive Units shall remain unvested and no unvested Incentive Units for such Participant shall vest thereafter; provided, that, notwithstanding the foregoing, upon the termination
of a Participant’s employment by the Company, VWR or their respective Subsidiaries by reason of such Participant’s death or Disability, all Incentive Units granted to a Participant pursuant to an Incentive Unit Grant Agreement which were
scheduled to vest pursuant to Section 2(a) above during the one-year period following the date of such termination of employment will instead vest as of the date of such termination of employment. 

3. Definitions 
 (a) “Issuance
Date” means, with respect to Incentive Units granted to a Participant pursuant to an Incentive Unit Grant Agreement, the date on which closing of any issuance of such Incentive Units subject to this Appendix takes place. 

(b) “Public Offering” means the sale in an underwritten public offering registered under the Securities Act of the equity
securities of the Company (or any successor thereto) approved by the Board. 
 (c) “Requisite Participants” means the
Participants that hold a majority of the outstanding Common Units that were initially subject to vesting under this Appendix. 
 (d)
“Subsidiary Public Offering” means the sale in an underwritten public offering registered under the Securities Act of equity securities of a Subsidiary of the Company. 

(e) “VWR” means VWR Funding, Inc., a Delaware corporation. 

4. Miscellaneous 
 (a) Conflicts.
The Plan and this Appendix are complementary to each other and shall be deemed as one. In the event of any conflict, whether explicit or implied, between (a) the provisions of this Appendix and the Plan, (b) the provisions of a Management
Unit Purchase Agreement (that expressly refers to this Appendix) and the Plan, or (c) provisions of a Management Unit Purchase Agreement (that expressly refers to this Appendix) and this Appendix, in each case, the Committee shall have the
power to resolve such conflict and to determine which provisions shall prevail. 

  
 - 9 - 

 (b) Amendments. Notwithstanding anything contained in the Plan or in any Management Unit
Purchase Agreement to the contrary, the Board or the Committee may amend or modify this Appendix from time to time as the Board or the Committee may deem advisable; provided that no such amendment or modification shall be made without the approval
of the Board to the extent such approval is required by law, agreement or the rules of any exchange upon which the Units are listed, and no such amendment or modification shall impair the rights of Participants under outstanding Management Unit
Purchase Agreements that expressly refer to this Appendix without the consent or approval of the Requisite Participants. 

*    *    *    *    * 

  
 - 10 - 

 AMENDMENT TO THE 

VARIETAL DISTRIBUTION HOLDINGS, LLC 

2007 SECURITIES PURCHASE PLAN 
 1.
Definitions. Capitalized terms used but not defined in this Amendment shall have the meanings assigned to them in the 2007 Varietal Distribution Holdings, LLC 2007 Securities Purchase Plan, as amended (the “Plan”). 

2. Amendment of the Plan. The Plan is hereby amended as follows: the definition of “Maximum Units” set forth in Section 1(c) of
Appendix B of the Plan is hereby deleted in its entirety and replaced with the following: 
 “Maximum Units. Unless otherwise
determined by the Board, the maximum number of Class B Common Units that may be issued pursuant to Management Unit Purchase Agreements to which this Appendix applies is 405,000. Class B Common Units issued subject to this Appendix are referred to
herein as “Incentive Units.”” 

*    *    *    *    * 

  
 - 11 - 

 AMENDMENT NO. 2 TO THE 

VARIETAL DISTRIBUTION HOLDINGS, LLC 

2007 SECURITIES PURCHASE PLAN 
 1.
Definitions. Capitalized terms used but not defined in this Amendment shall have the meanings assigned to them in the 2007 Varietal Distribution Holdings, LLC 2007 Securities Purchase Plan, as amended (the “Plan”). 

2. Amendment of the Plan. The Plan is hereby amended as follows: 
  

	 	(a)	Section 2(e) of Appendix A of the Plan is hereby deleted in its entirety and replaced with the following: 

“(e) Vesting Limits. Notwithstanding anything contained in Section 2(c) or (d) of this Appendix to the
contrary, in the event that all or a portion of the Incentive Units have not vested on or prior to the earlier of (i) the Determination Date for the Measurement Period ending December 31, 2015 and (ii) the date on which Executive is
no longer employed by the Company, VWR or any of their respective Subsidiaries, such unvested Incentive Units shall remain unvested and no unvested Incentive Units shall vest thereafter. Further, in no event shall any Common Unit vest more than
once.” 
  

	 	(b)	The definitions of “Adjusted EBITDA Amount” set forth in Section 3(a), “Maximum EBITDA Amount” set forth in Section 3(b), the definition of “Measurement
Period” set forth in Section 3(c), the definition of “Minimum EBITDA Amount” set forth in Section 3(d), and the definition of “Trigger Date” set forth in Section 3(f) of Appendix A of the
Plan are hereby deleted in their entirety and replaced with the following: 

 “(a) “Adjusted EBITDA
Amount” means, with respect to a Measurement Period, VWR and its Subsidiaries’ earnings before net interest expense, income taxes, depreciation, amortization and fees pursuant to the Management Services Agreement (as defined in the LLC
Agreement), as it may be amended from time to time, in each case, for such Measurement Period, determined on a consolidated basis based upon the annual financial statements for VWR for the applicable Measurement Period filed with the Securities and
Exchange Commission, as adjusted to reflect (w) the adjustments reflected in the description of “Adjusted EBITDA” contained in VWR’s Current Report on Form 8-K filed in connection with management’s teleconference to discuss
the annual financial results for such Measurement Period, (x) constant currency translation exchange rates as reflected in VWR International, LLC’s 2011 Internal Operating Plan (y) for any business acquired after January 1, 2012,
a constant currency translation exchange rate equal to the applicable Dollar to foreign currency exchange rate in effect on 

  
 - 12 - 

 
the closing date of such acquisition, and (z) for the Measurement Period ending December 31, 2015, a pro forma adjustment for any business acquired in such Measurement Period to reflect
the projected full year Adjusted EBITDA Amount as if such acquisition had occurred on January 1, 2015. Adjusted EBITDA Amount shall be determined by the Board. 

(b) “Maximum EBITDA Amount” means $500 million. 

(c) “Measurement Period” means each of the following four periods: (i) the fiscal year ending December 31, 2012,
(ii) the fiscal year ending December 31, 2013, (iii) the fiscal year ending December 31, 2014, and (iv) the fiscal year ending December 31, 2015. 

(d) “Minimum EBITDA Amount” means $457.6 million. 

(f) “Trigger Date” a Trigger Date shall have occurred as of the Determination Date for the Measurement Period ending
December 31, 2015 if after giving effect to any vesting that occurs on such date any of the Incentive Units remain unvested.” 

*    *    *    *    * 

  
 - 13 -

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