Document:

Amendment No. 2 to Amended and Restated Rights Agreement

 Exhibit 4.1 
  
 AMENDMENT NO. 2 
 TO 
 AMENDED AND RESTATED RIGHTS AGREEMENT 
  
 THIS AMENDMENT NO. 2 (this “Amendment”) to Amended and Restated Rights Agreement dated as of July 29,
1999 between NOVOSTE CORPORATION, a Florida corporation (the “Company”), and AMERICAN STOCK TRANSFER & TRUST COMPANY, a banking corporation organized under the laws of New York, as rights agent (the “Rights
Agent”), as amended pursuant to Amendment No. 1 to Amended and Restated Rights Agreement, dated as of May 18, 2005 (as amended, the “Rights Agreement”), is entered into this 30th day of January, 2006. 
  
 WHEREAS, the Company and the Rights Agent are currently parties to the Rights Agreement and desire to amend the Rights Agreement on the terms and
conditions hereinafter set forth; and 
  
 WHEREAS, for purposes of
this Amendment, capitalized terms not otherwise defined herein shall have the respective meanings set forth in the Rights Agreement, as amended by this Amendment; 
  
 NOW, THEREFORE, in consideration of the premises and the mutual agreements herein set forth, the parties hereby agree as
follows: 
  
 1. Amendment to Section 1.
Section 1(a) of the Rights Agreement is hereby amended (a) by deleting the percentage number “15%” each time it appears therein and replacing it with the percentage number “30%” and (b) by deleting the percentage
number “20%” each time it appears therein and replacing it with the percentage number “30%”. 
  
 2. Effective Date. This Amendment shall become effective as of January 30, 2006. 
  
 3. Other Terms Unchanged. The Rights Agreement, as amended by this Amendment, shall remain and continue in full force
and effect and is in all respects agreed to, ratified and confirmed hereby. Any reference to the Rights Agreement after the date set forth above shall be deemed to be a reference to the Rights Agreement, as amended by this Amendment. 
  
 4. Benefits. Nothing in the Rights Agreement, as amended by this
Amendment, shall be construed to give to any Person other than the Company, the Rights Agent and the registered holders of the Rights Certificates (and, prior to the Distribution Date, the registered holders of the Common Stock) any legal or
equitable right, remedy or claim under the Rights Agreement, as amended by this Amendment; but the Rights Agreement, as amended by this Amendment, shall be for the sole and exclusive benefit of the Company, the Rights Agent and the registered
holders of the Rights Certificates (and, prior to the Distribution Date, registered holders of the Common Stock). 

 5. Descriptive Headings. Descriptive headings of the several Sections of this Amendment are
inserted for convenience only and shall not control or affect the meaning or construction of any of the provisions hereof. 
  
 6. Governing Law. This Amendment shall be deemed to be a contract made under the laws of the State of Florida and for all purposes shall be
governed by and construed in accordance with the laws of such State. 
  
 7. Counterparts. This Amendment may be executed in any number of counterparts. It shall not be necessary that the signature of or on behalf of each party appears on each counterpart, but it shall be sufficient that the signature of
or on behalf of each party appears on one or more of the counterparts. All counterparts shall collectively constitute a single agreement. It shall not be necessary in any proof of this Amendment to produce or account for more than a number of
counterparts containing the respective signatures of or on behalf of all of the parties. 
  
 8. Fax Transmission. A facsimile, telecopy or other reproduction of this Amendment may be executed by one or more parties hereto, and an executed copy of this Amendment may be delivered by one or more parties
hereto by facsimile or similar instantaneous electronic transmission device pursuant to which the signature of or on behalf of such party can be seen, and such execution and delivery shall be considered valid, binding and effective for all purposes.
At the request of any party hereto, all parties agree to execute an original of the Amendment as well as any facsimile, telecopy or other reproduction thereof. 
  

[Signatures on Next Page] 

 IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be duly executed and attested, all
as of January 30, 2006. 
  

			
	NOVOSTE CORPORATION
		
	By:	 	 /s/ Alfred J. Novak

	Name:	 	Alfred J. Novak
	Title:	 	President and Chief Executive Officer
	
	AMERICAN STOCK TRANSFER &
	TRUST COMPANY, as Rights Agent
		
	By:	 	 /s/ Isaac J. Kagan

	Name:	 	Isaac J. Kagan
	Title:	 	Vice PresidentAmendment No. 3 to Marketing Representation Agreement

 Exhibit 10.1 
  
 AMENDMENT NO. 3 TO MARKETING REPRESENTATION AGREEMENT 
  
 This Amendment No. 3 to Marketing Representation Agreement (the “Amendment No. 3”) is made this
27th day of January, 2006, by and among (i) Novoste Corporation, a Florida corporation with its principal place
of business at 4350 International Boulevard, Norcross, Georgia 30093 (“Novoste”), (ii) Best Vascular, Inc., a Delaware corporation with its principal place of business at 7643 Fullerton Road, Springfield, Virginia 22153
(“Representative”), and (iii) Best Medical International, Inc., a Virginia corporation which is an affiliate of Representative, with its principal place of business at 7643 Fullerton Road, Springfield, Virginia 22153
(“BMI”); 
  
 WHEREAS, Novoste, Representative and
BMI entered into that certain Marketing Representation Agreement, dated as of August 25, 2005, as amended October 12, 2005 pursuant to Amendment No. 1 to Marketing Representation Agreement and as further amended November 30, 2005
pursuant to Amendment No. 2 to Marketing Representation Agreement (as amended, the “Marketing Representation Agreement”), pursuant to which Novoste engaged Representative to market, demonstrate and solicit orders for various products
with respect to Seller’s VBT Business; and 
  
 WHEREAS, Novoste, Representative and BMI desire to amend the provisions of the Marketing Representation Agreement relating to its term; and 
  
 WHEREAS, the parties hereto are concurrently with this Amendment No. 3 entering into an amendment to the Amended and Restated Asset Purchase
Agreement, dated as of October 12, 2005, as amended November 30, 2005; and 
  
 WHEREAS, for purposes of this Amendment No. 3, capitalized terms not otherwise defined herein shall have the respective meanings set forth in the Marketing Representation Agreement; 
  
 NOW, THEREFORE, in consideration of the mutual promises contained
herein, the recitals set forth above, which are hereby incorporated by reference, and for other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the parties agree as follows: 
  
 1. Term. Section 7.1(c) shall be amended by deleting the date
“February 15, 2006” and inserting in lieu thereof the date “March 31, 2006”. 
  
 2. Other Terms Unchanged. The Marketing Representation Agreement, as amended by this Amendment No. 3, shall remain and continue in full

 force and effect, shall constitute a legal, valid and binding obligation of Novoste, Representative and BMI and is in all
respects agreed to, ratified and confirmed hereby. Any reference to the Marketing Representation Agreement after the date first set forth above shall be deemed to be a reference to the Marketing Representation Agreement, as amended by this Amendment
No. 3. 
  
 3. Governing Law. This Amendment No. 3
shall be governed by the substantive laws of the State of Georgia, without regard to conflict-of-laws issues. 
  
 4. Counterparts. This Amendment No. 3 may be executed in two or more counterparts, each of which shall be deemed an original, but all of which
together shall constitute one and the same document. 
  
 5.
Titles and Captions. Section headings are used for convenience and shall not affect the interpretation or construction of any provision of this Amendment No. 3. 
  
 [Remainder of Page Intentionally Left Blank] 

 Accepted and agreed to by the parties by their duly authorized representatives as of the date first set
forth above. 
  

							
	NOVOSTE CORPORATION	 	BEST VASCULAR, INC.
				
	By:	 	 /s/ Alfred J. Novak

	 	By:	 	 /s/ Shawn R. Weingast

	Title:	 	President and Chief Executive Officer	 	Title:	 	General Counsel
	Date:	 	January 27, 2006	 	Date:	 	January 27, 2006
			
	BEST MEDICAL INTERNATIONAL, INC.	 	 	 	 
				
	By:	 	 /s/ Alfred J. Novak

	 	 	 	 
	Title:	 	General Counsel	 	 	 	 
	Date:	 	January 27, 2006Second Amendment to Letter Agreement

 Exhibit 10.2 
  
 SECOND AMENDMENT TO LETTER AGREEMENT 
  
 THIS SECOND AMENDMENT TO LETTER AGREEMENT (the “Amendment”) is entered into effective the 1st day of February, 2006, by Novoste Corporation, a Florida corporation (hereinafter referred to as the “Company”) and
Daniel G. Hall (hereinafter referred to as the “Executive”). The Company and Executive are hereinafter referred to collectively, as the “Parties.” 
  
 W I T N E S S E T H: 
  
 WHEREAS, the Parties have entered into a Letter Agreement dated November 11, 2005, pursuant to which the date of Executive’s termination
of employment with the Company was established as December 31, 2005 and pursuant to which the Executive is entitled to receive certain payments upon the termination of his employment; and 
  
 WHEREAS, the Company amended the Letter Agreement effective
January 1, 2006, to extend the Executive’s employment termination date to January 31, 2006, and 
  
 WHEREAS, the Company desires to further extend Executive’s employment beyond January 31, 2006. 
  
 NOW, THEREFORE, in consideration of the promises and mutual covenants
contained herein and other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the Parties hereby agree as follows: 
  

1. Termination of Employment: The terms of paragraph 1 of the Letter Agreement shall be altered and amended so that the Executive shall continue
to be employed by the Company through February 28, 2006. 
  
 2. Certain Payments: Paragraph 2 of the letter Agreement, as amended, shall be further amended by adding the following paragraph: 
  

	 	(iv)	a fourth payment (the “Fourth Payment”) in the amount of $16,250, less applicable deductions, including, without limitation, federal and state withholding, to be paid on
February 28, 2006, provided, however, that the Executive shall not receive the Fourth Payment if the Executive voluntarily terminates employment with the Company prior to February 28, 2006. 

 3. All other and further terms and provisions of the Letter Agreement shall remain in full force and
effect as entered into by the Parties on November 11, 2005. 
  
 IN WITNESS WHEREOF, the Parties have executed this Second Amendment to the Letter Agreement as of the date indicated by their respective names. 
  

					
	Date:	 	 
		
	January 30, 2006	 	 /s/ Daniel G. Hall

	 	 	DANIEL G. HALL
		
	 	 	NOVOSTE CORPORATION
		
	Date:	 	 
			
	January 30, 2006	 	By:	 	 /s/ Alfred J. Novak

	 	 	Name:	 	Alfred J. Novak
	 	 	Title:	 	PRESIDENT AND CHIEF EXECUTIVE OFFICER

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