Document:

Form of Stock Option Agreement

 Exhibit 10.7 
 EXELIXIS, INC. 
 2000
NON-EMPLOYEE DIRECTORS’ STOCK OPTION PLAN 
 STOCK OPTION AGREEMENT 

(NONSTATUTORY STOCK OPTION) 

Pursuant to your Certificate of Stock Option Grant on the Smith Barney Stock Plan Services website (“the Grant Certificate”)
and this Stock Option Agreement, Exelixis, Inc. (the “Company”) has granted you an option under its 2000 Non-Employee Directors’ Stock Option Plan (the “Plan”) to purchase the number of shares of the Company’s Common
Stock indicated in your Grant Certificate at the exercise price indicated in your Grant Certificate. Defined terms not explicitly defined in this Stock Option Agreement but defined in the Plan shall have the same definitions as in the Plan.

 The details of your option are as follows: 
 1. VESTING. Subject to the limitations contained herein, your option will vest as provided in your Grant Certificate, provided that vesting will cease upon the
termination of your Continuous Service. 
 2. NUMBER OF SHARES
AND EXERCISE PRICE. The number of shares of Common Stock subject to your option and your exercise price per share referenced in your Grant Certificate may be adjusted from time to time
for Capitalization Adjustments, as provided in the Plan. 
 3. DATES OF
EXERCISE. The option shall be exercisable for shares of Common Stock in one or more installments as specified in the Grant Certificate. As your option becomes exercisable for such installments, those installments
shall accumulate, and the option shall remain exercisable for the accumulated installments until the Expiration Date or sooner termination of the option term under Section 7 below. 

4. METHOD OF PAYMENT. Payment of the exercise price is due in
full upon exercise of all or any part of your option. You may elect to make payment of the exercise price in cash or by check or by one or more of the following: 
 (a) Provided that at the time of exercise the Common Stock is publicly traded and quoted regularly in The Wall Street Journal, pursuant to a program developed under Regulation T as
promulgated by the Federal Reserve Board that, prior to the issuance of Common Stock, results in either the receipt of cash (or check) by the Company or the receipt of irrevocable instructions to pay the aggregate exercise price to the Company from
the sales proceeds. 
 (b) Provided that at the time of exercise the Common Stock is publicly traded and quoted regularly
in The Wall Street Journal, by delivery of already-owned shares of Common Stock either that you have held for the period required to avoid a charge to the 

  
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Company’s reported earnings (generally six months) or that you did not acquire, directly or indirectly from the Company, that are owned free and clear of any liens, claims, encumbrances or
security interests, and that are valued at Fair Market Value on the date of exercise. “Delivery” for these purposes, in the sole discretion of the Company at the time you exercise your option, shall include delivery to the Company of your
attestation of ownership of such shares of Common Stock in a form approved by the Company. Notwithstanding the foregoing, you may not exercise your option by tender to the Company of Common Stock to the extent such tender would violate the
provisions of any law, regulation or agreement restricting the redemption of the Company’s stock. 
 5.
WHOLE SHARES. You may exercise your option only for whole shares of Common Stock. 
 6. SECURITIES LAW COMPLIANCE. Notwithstanding anything to the contrary contained herein, you may not exercise your option unless
the shares of Common Stock issuable upon such exercise are then registered under the Securities Act or, if such shares of Common Stock are not then so registered, the Company has determined that such exercise and issuance would be exempt from the
registration requirements of the Securities Act. The exercise of your option must also comply with other applicable laws and regulations governing your option, and you may not exercise your option if the Company determines that such exercise would
not be in material compliance with such laws and regulations. 
 7. TERM. The term
of your option commences on the Date of Grant and expires upon the earliest of the following: 
 (a) three
(3) years after the termination of your Continuous Service for any reason (including your Disability or death), provided that if during any part of such three- (3-) year period your option is not exercisable solely because of the condition set
forth in the preceding paragraph relating to “Securities Law Compliance,” your option shall not expire until the earlier of the Expiration Date or until it shall have been exercisable for an aggregate period of three (3) years after
the termination of your Continuous Service; or 
 (b) the Expiration Date indicated in your Grant Certificate.

 8. Exercise. 
 (a) You may exercise your option during its term by delivering a Cash Letter of Authorization or other appropriate form (in a form designated by the Company) together with the exercise price to the
Secretary of the Company, or to such other person as the Company may designate, during regular business hours, together with such additional documents as the Company may then require. 

(b) By exercising your option you agree that, as a condition to any exercise of your option, the Company may require you to enter
into an arrangement providing for the payment by you to the Company of any tax withholding obligation of the Company arising by reason of the exercise of your option. 

  
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 (c) TRANSFERABILITY. Your option is not
transferable, except (i) by will or by the laws of descent and distribution, and (ii) to such further extent as permitted by the Rule as to Use of Form S-8 specified in the General Instructions of the Form S-8 Registration Statement under
the Securities Act. Your option is exercisable during your life only by you or a transferee satisfying the above-stated conditions. The right of a transferee to exercise the transferred portion of your option after termination of your Continuous
Service shall terminate in accordance with your right to exercise your option as specified in your option. In the event that your Continuous Service terminates due to your death, your transferee will be treated as a person who acquired the right to
exercise your option by bequest or inheritance. In addition to the foregoing, the Company may require, as a condition of the transfer of your option to a trust or by gift, that your transferee enter into an option transfer agreement provided by, or
acceptable to, the Company. The terms of your option shall be binding upon your transferees, executors, administrators, heirs, successors, and assigns. Notwithstanding the foregoing, by delivering written notice to the Company, in a form
satisfactory to the Company, you may designate a third party who, in the event of your death, shall thereafter be entitled to exercise your option. 
 9. OPTION NOT A SERVICE CONTRACT. Your option is not an employment or service contract, and nothing
in your option shall be deemed to create in any way whatsoever any obligation on your part to continue in the employ of the Company or an Affiliate, or of the Company or an Affiliate to continue your employment. In addition, nothing in your option
shall obligate the Company or an Affiliate, their respective stockholders, Boards of Directors, Officers or Employees to continue any relationship that you might have as a Director or Consultant for the Company or an Affiliate. 

10. NOTICES. Any notices provided for in your option or the Plan shall be given in writing
and shall be deemed effectively given upon receipt or, in the case of notices delivered by mail by the Company to you, five (5) days after deposit in the United States mail, postage prepaid, addressed to you at the last address you provided to
the Company. 
 11. GOVERNING PLAN DOCUMENT. Your
option is subject to all the provisions of the Plan, the provisions of which are hereby made a part of your option, and is further subject to all interpretations, amendments, rules and regulations which may from time to time be promulgated and
adopted pursuant to the Plan. In the event of any conflict between the provisions of your option and those of the Plan, the provisions of the Plan shall control. 

  
 3Offer Letter Agreement between Exelixis, Inc. and Lupe M. Rivera

 Exhibit 10.19 
 January 7, 2002 
 Lupe M. Rivera 
 Dear Lupe: 
 We are proud to invite you to join our team. 

Our offer of employment is to join Exelixis, Inc. Your title will be that of Associate Director, Human Resources reporting to Lisa Stemmerich, Director,
Human Resources in our Human Resources department. Other terms of employment include: 
 Compensation: You will receive four thousand
four hundred fifty-eight dollars and thirty-three cents ($4,458.33) per pay period. There are two pay periods per month. You will receive a sign-on bonus of eleven thousand dollars ($11,000.00) payable on the first pay date after hire. Should you
elect to voluntarily terminate employment with the Company within twelve (12) months of your hire date, the sign-on bonus will be entirely re-paid by you to the Company on your last date of employment. 

Options for Equity: You will also be eligible to receive a stock option for twenty-five thousand (25,000) shares of
Exelixis stock pursuant to our standard Stock Plan and subject to approval by the Board of Directors. Options vest at the rate of 1/4th after one year and 1/48th every month thereafter over a total of four years. 
 Benefits: All full-time employees of Exelixis, Inc. enjoy a generous benefits package, which is outlined on the attached Summary of Benefits. 

Performance Review: Focal reviews will take place annually during the month of December, at which time your performance will be reviewed.

 Lupe M. Rivera 
 January 7, 2002 
 Page Two 
 Start Date: On Tuesday, January 22, 2002. 
 Confidentiality: As you are aware,
it is very important for us to protect our confidential information and proprietary material. Therefore, as a condition of employment, you will need to sign the attached Proprietary Information and Inventions Agreement. 

Other: In addition to performing the duties and responsibilities of your position, you will be expected to perform other duties and
responsibilities that may be assigned to you from time to time. No provision of this letter shall be construed to create an express or implied employment contract for a specific period of time. Either you or the Company may terminate this employment
relationship at any time, with or without cause. This letter shall be governed by the laws of the State of California. Also, by signing this letter, you are indicating that you are legally authorized to work in the U.S. 

You may accept this offer of employment by signing both copies of this letter and Proprietary Information and Invention Agreements and returning one of
each to Lisa Stemmerich, Director, Human Resources 
 Lupe, we look forward to your coming on board! 

Sincerely, 
 /s/ Lisa Stemmerich 

Lisa Stemmerich 
 Director of Human Resources

 ACCEPTED BY: 
  

			
	 /s/ Lupe M. Rivera
	    	January 8, 2002
	Lupe M. Rivera	    	Date

 Enclosures: 

Benefit Summary 
 Confidentiality Agreement

 DE-4 (optional) 
 Direct Deposit Form
(optional) 
 Employee Information Form 

I-9 
 Insider Trading Policy 

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