Document:

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                                                                    Exhibit 4.25

THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE BEEN ACQUIRED FOR INVESTMENT
AND HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED OR
STATE SECURITIES LAWS.  THESE SECURITIES MAY NOT BE SOLD OR TRANSFERRED IN THE
ABSENCE OF SUCH REGISTRATION OR AN EXEMPTION THEREFROM UNDER SAID ACT OR STATE
SECURITIES LAWS.

No.  7              Right to Purchase Shares of Common Stock of OraPharma, Inc.

                                ORAPHARMA, INC.

                         Common Stock Purchase Warrant

     This is to certify that, FOR VALUE RECEIVED, HealthCap CoInvest KB (the
"Holder"), is entitled to purchase, subject to the provisions of this Warrant,
from OraPharma, Inc., a Delaware corporation (the "Company"), 35,130 fully paid,
validly issued and nonassessable shares of Common Stock, par value $.001 per
share, of the Company (the "Common Stock") at an exercise price of $6.46 per
share.  The number of shares of Common Stock to be received upon the exercise of
this Warrant and the price to be paid for each share of Common Stock may be
adjusted from time to time as hereinafter set forth.  The shares of Common Stock
deliverable upon such exercise, and as adjusted from time to time, are
hereinafter sometimes referred to as "Warrant Shares" and the exercise price of
a share of Common Stock in effect at any time and as adjusted from time to time
is hereinafter sometimes referred to as the "Exercise Price".

     1.  EXERCISE OF WARRANT.
         -------------------

         a.  Exercise for Cash.  This Warrant may be exercised in whole or in
part at any time or from time to time starting from a period of twelve months
and five days after issue until 5:00 p.m. Eastern Standard Time on December 23,
2006 (the "Exercise Period"). This Warrant may be exercised by presentation and
surrender hereof to the Company at its principal office, or at the office of its
stock transfer agent, if any, with the Purchase Form annexed hereto duly
executed and accompanied by payment of the Exercise Price for the number of
Warrant Shares specified in such form.  The Exercise Price may be paid by bank
check, wire transfer or cancellation of indebtedness.  As soon as practicable
after each such exercise of this Warrant, but not later than seven (7) days from
the date of such exercise, the Company shall issue and deliver to the Holder a
certificate for the Warrant Shares issuable upon such exercise, registered in
the name of the Holder.  If this Warrant should be exercised in part only, the
Company shall, upon surrender of this Warrant for cancellation, execute and
deliver a new Warrant evidencing the rights of the Holder thereof to purchase
the balance of the Warrant Shares purchasable thereunder.  Upon receipt by the
Company of this Warrant at its office, or by the stock transfer agent of the
Company at its office, in proper form for exercise, the Holder shall be deemed
to be the holder of record of the shares of Common Stock issuable upon such
exercise, notwithstanding that the stock transfer books of the Company shall
then be closed or that certificates representing such shares of Common Stock
shall not then be physically delivered to the Holder.
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         b.  Warrant Exchange.  At any time during the Exercise Period, the
Holder may, at its option, exchange this Warrant, in whole or in part (a
"Warrant Exchange"), into the number of Warrant Shares determined in accordance
with this Section 1(b), by surrendering this Warrant at the principal office of
the Company or at the office of its stock transfer agent, accompanied by a
notice stating the Holder's intent to effect such exchange, the number of
Warrant Shares to be exchanged and the date on which the Holder requests that
such Warrant Exchange occur (the "Notice of Exchange").  The Warrant Exchange
shall take place on the date specified in the Notice of Exchange or, if later,
the date the Notice of Exchange is received by the Company (the "Exchange
Date").  Certificates for the shares issuable upon such Warrant Exchange and, if
applicable, a new warrant of like tenor evidencing the balance of the shares
remaining subject to this Warrant, shall be issued as of the Exchange Date and
delivered to the Holder within seven (7) days following the Exchange Date.  In
connection with any Warrant Exchange, this Warrant shall represent the right to
subscribe for and acquire the number of Warrant Shares equal to (i) the number
of Warrant Shares specified by the Holder in its Notice of Exchange (the "Total
Number") less (ii) the number of Warrant Shares equal to the quotient obtained
by dividing (A) the product of the Total Number and the existing Exercise Price
by (B) the Fair Market Value, provided that any fractional shares determined by
this calculation shall be represented by the issuance of a new Warrant.  "Fair
Market Value" shall be determined as follows: (1) if the Common Stock is listed
on a national securities exchange or admitted to unlisted trading privileges on
such exchange or listed for trading on the Nasdaq Stock Market, the Fair Market
Value shall be the average of the last reported sale prices of the Common Stock
on such exchange or system for the twenty (20) business days ending on the last
business day prior to the date for which the determination is being made; or (2)
if the Common Stock is not so listed or admitted to unlisted trading privileges,
the Fair Market Value shall be the average of the last reported bid and asked
prices reported by the National Quotation Bureau, Inc. for the twenty (20)
business days ending on the last business day prior to the date for which the
determination is being made; or (3) if the Common Stock is not so listed or
admitted to unlisted trading privileges and bid and asked prices are not so
reported, the Fair Market Value shall be an amount, not less than book value
thereof as at the end of the most recent fiscal quarter of the Company ending
prior to the Exchange Date, determined in such reasonable manner as may be
prescribed by the Board of Directors of the Company.

     2.  RESERVATION OF SHARES.  The Company shall at all times reserve for
issuance and/or delivery upon exercise of this Warrant such number of shares of
its Common Stock as shall be required for issuance and delivery upon exercise of
this Warrant.

     3.  FRACTIONAL SHARES.  No fractional shares of Common Stock shall be
issued upon the exercise of this Warrant.  With respect to any fraction of a
share called for upon any exercise hereof, the Company shall pay to the Holder
an amount in cash equal to such fraction multiplied by the Fair Market Value of
a share of Common Stock.

     4.  ANTIDILUTION PROVISIONS.  In the event the Common Stock is changed by
reason of a stock split, reverse stock split, stock dividend or recapitalization
or is converted into or exchanged for other securities as a result of a merger,
consolidation or reorganization in which the Company is the surviving
corporation, appropriate adjustments shall be made in the terms of this Warrant,
or additional warrants shall be granted to the Holder as shall be equitable and
appropriate, or an adjustment in the number and class of shares allocated to,
and the Exercise Price of, this Warrant shall likewise be made.

     5.  CERTAIN EXTRAORDINARY TRANSACTIONS.  In the event the Common Stock is

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exchanged for securities, cash or other property of any other corporation or
entity as the result of a reorganization, merger or consolidation in which the
Company is not the surviving corporation, the dissolution or liquidation of the
Company, or the sale of all or substantially all the assets of the Company, the
Board of Directors of the Company or the board of directors of any successor
corporation or entity may, in its discretion, as to the unexercised portion of
this Warrant, (a) provide for payment of an amount equal to the excess of the
fair market value of the Warrant Shares, as determined by the Board of Directors
of the Company or such board, over the Exercise Price of such Warrant Shares as
of the date of the transaction, in exchange for the surrender of the right to
exercise this Warrant, or (b) provide for the assumption of this Warrant, or the
substitution therefor of new warrants, by the successor corporation or entity.

     6.  LOSS OF WARRANT.  Upon receipt by the Company of evidence satisfactory
to it of the loss, theft, destruction or mutilation of this Warrant, and (in the
case of loss, theft or destruction) of reasonably satisfactory indemnification,
and upon surrender and cancellation of this Warrant, if mutilated, the Company
will execute and deliver a new warrant of like tenor and date.

     7.  NO RIGHTS AS STOCKHOLDER.  The Holder shall not, as holder of this
Warrant, be entitled to vote, if applicable, or to receive dividends or to be
deemed the holder of Common Stock that may at any time be issuable upon exercise
of this Warrant for any purpose whatsoever, nor shall anything contained herein
be construed to confer upon the Holder, as such, any of the rights of a
stockholder of the Company or, if applicable, any right to vote for the election
of directors or upon any matter submitted to stockholders at any meeting
thereof, or to give or withhold consent to any corporate action (whether upon
any recapitalization, issue or reclassification of stock, change of par value or
change of stock to no par value, consolidation, merger or conveyance or
otherwise), or to receive notice of meetings, or to receive dividends or
subscription rights, until such holder shall have exercised the Warrant and been
issued the Warrant Shares in accordance with the provisions hereof.

     8.  NON-TRANSFERABILITY.  Neither this Warrant nor any Warrant Shares
shall be registered under the Securities Act of 1933, as amended, and applicable
state securities laws.  Therefore, the Company shall require, as a condition of
allowing the transfer or exchange of this Warrant or such Warrant Shares, that
the Holder of this Warrant or such Warrant Shares, as the case may be, furnish
to the Company an opinion of counsel reasonably acceptable to the Company to the
effect that such transfer or exchange will be exempt from the registration and
prospectus delivery requirements under the Securities Act of 1933, as amended,
and applicable state securities laws.  The certificates evidencing the Warrant
Shares shall bear a legend to the effect that the Warrant Shares evidenced by
such certificate have not been registered under the Securities Act of 1933, as
amended, and applicable state securities laws and are, therefore, subject to
restrictions on transfer.

     9.  INVESTMENT REPRESENTATIONS AND WARRANTIES.  The Holder hereby
represents and warrants to the Company that (a) it has knowledge and experience
in financial and business matters sufficient to enable it to evaluate the merits
and risks of an investment in the Company; (b) it has assets sufficient to
enable it to bear the economic risk of its investment in this Warrant and the
Warrant Shares and is an "accredited investor" as defined in Rule 501 under the
Securities Act of 1933, as amended; (c) it is acquiring this Warrant and, upon
exercise, will acquire the Warrant Shares, for its own account, and not with a
view to, or for sale in connection with, any distribution thereof; (d) it or its
representatives have received from the Company such information with respect to
the Company as it has deemed necessary and relevant in connection with this
Warrant and the Warrant Shares and it has had the

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opportunity, directly or through such representatives, to ask questions of and
receive answers from persons acting on behalf of the Company necessary to verify
the information so obtained; and (e) it and its officers, directors, employees
and agents have not employed any broker or finder or incurred any liability for
any brokerage or finder's fees or commissions or similar payments in connection
with this Warrant and the Warrant Shares.

     10. GOVERNING LAW.  This Agreement and all amendments, modifications,
alterations, or supplements hereto shall be construed under and governed by the
laws of the State of New Jersey and the United States of America, without regard
to the principles of conflicts of law thereof.

     11. MISCELLANEOUS.  Except as provided in Sections 4 and 5 hereof, this
Warrant and any term hereof may be changed, waived, discharged or terminated
only by an instrument in writing signed by the party against which enforcement
of such change, waiver, discharge or termination is sought.  The headings in
this Warrant are for purposes of reference only and shall not limit or otherwise
affect any of the terms hereof.  The invalidity or unenforceability of any
provision hereof shall in no way affect the validity or enforceability of any
other provision.

     12. EXPIRATION.  The right to exercise this Warrant shall expire at 5:00
P.M. Eastern Standard Time on December 23, 2006.

     This Warrant is executed as of the date and year first written above.

Witness:                                ORAPHARMA, INC.

                                        By: /s/ Michael Kishbauch
---------------------------                ----------------------------
                                           Michael Kishbauch, President

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                             FORM OF SUBSCRIPTION
                  (To be signed only on exercise of Warrant)

TO: OraPharma, Inc.

     The undersigned, the holder of the within Warrant, hereby irrevocably
elects to exercise this Warrant for, and to purchase thereunder _______ shares
of Common Stock, $.001 par value per share, of OraPharma, Inc. and herewith
makes payment of $__________ therefor, and requests that the certificates for
such shares be issued in the name of, and delivered to the undersigned at
_____________________________.

Dated:                          _____________________________________________
                                (Signature must conform to name of holder as
                                specified on the face of the Warrant)

                                __________________________________
                                (Address)

                                __________________________________<PAGE>

                                                                    Exhibit 4.26

THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE BEEN ACQUIRED FOR INVESTMENT
AND HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED OR
STATE SECURITIES LAWS.  THESE SECURITIES MAY NOT BE SOLD OR TRANSFERRED IN THE
ABSENCE OF SUCH REGISTRATION OR AN EXEMPTION THEREFROM UNDER SAID ACT OR STATE
SECURITIES LAWS.

No.  8              Right to Purchase Shares of Common Stock of OraPharma, Inc.

                                ORAPHARMA, INC.

                         Common Stock Purchase Warrant

      This is to certify that, FOR VALUE RECEIVED, Oak Investment Partners VI,
Limited Partnership  (the "Holder"), is entitled to purchase, subject to the
provisions of this Warrant, from OraPharma, Inc., a Delaware corporation (the
"Company"), 51,886 fully paid, validly issued and nonassessable shares of Common
Stock, par value $.001 per share, of the Company (the "Common Stock") at an
exercise price of $6.46 per share.  The number of shares of Common Stock to be
received upon the exercise of this Warrant and the price to be paid for each
share of Common Stock may be adjusted from time to time as hereinafter set
forth.  The shares of Common Stock deliverable upon such exercise, and as
adjusted from time to time, are hereinafter sometimes referred to as "Warrant
Shares" and the exercise price of a share of Common Stock in effect at any time
and as adjusted from time to time is hereinafter sometimes referred to as the
"Exercise Price".

      1.  EXERCISE OF WARRANT.
          -------------------

          a.   Exercise for Cash.  This Warrant may be exercised in whole or in
part at any time or from time to time starting from a period of twelve months
and five days after issue until 5:00 p.m. Eastern Standard Time on December 23,
2006 (the "Exercise Period"). This Warrant may be exercised by presentation and
surrender hereof to the Company at its principal office, or at the office of its
stock transfer agent, if any, with the Purchase Form annexed hereto duly
executed and accompanied by payment of the Exercise Price for the number of
Warrant Shares specified in such form.  The Exercise Price may be paid by bank
check, wire transfer or cancellation of indebtedness.  As soon as practicable
after each such exercise of this Warrant, but not later than seven (7) days from
the date of such exercise, the Company shall issue and deliver to the Holder a
certificate for the Warrant Shares issuable upon such exercise, registered in
the name of the Holder.  If this Warrant should be exercised in part only, the
Company shall, upon surrender of this Warrant for cancellation, execute and
deliver a new Warrant evidencing the rights of the Holder thereof to purchase
the balance of the Warrant Shares purchasable thereunder.  Upon receipt by the
Company of this Warrant at its office, or by the stock transfer agent of the
Company at its office, in proper form for exercise, the Holder shall be deemed
to be the holder of record of the shares of Common Stock issuable upon such
exercise, notwithstanding that the stock transfer books of the Company shall
then be closed or that certificates representing such shares of Common Stock
shall not then be physically delivered to the Holder.
<PAGE>

          b.   Warrant Exchange.  At any time during the Exercise Period, the
Holder may, at its option, exchange this Warrant, in whole or in part (a
"Warrant Exchange"), into the number of Warrant Shares determined in accordance
with this Section 1(b), by surrendering this Warrant at the principal office of
the Company or at the office of its stock transfer agent, accompanied by a
notice stating the Holder's intent to effect such exchange, the number of
Warrant Shares to be exchanged and the date on which the Holder requests that
such Warrant Exchange occur (the "Notice of Exchange").  The Warrant Exchange
shall take place on the date specified in the Notice of Exchange or, if later,
the date the Notice of Exchange is received by the Company (the "Exchange
Date").  Certificates for the shares issuable upon such Warrant Exchange and, if
applicable, a new warrant of like tenor evidencing the balance of the shares
remaining subject to this Warrant, shall be issued as of the Exchange Date and
delivered to the Holder within seven (7) days following the Exchange Date.  In
connection with any Warrant Exchange, this Warrant shall represent the right to
subscribe for and acquire the number of Warrant Shares equal to (i) the number
of Warrant Shares specified by the Holder in its Notice of Exchange (the "Total
Number") less (ii) the number of Warrant Shares equal to the quotient obtained
by dividing (A) the product of the Total Number and the existing Exercise Price
by (B) the Fair Market Value, provided that any fractional shares determined by
this calculation shall be represented by the issuance of a new Warrant.  "Fair
Market Value" shall be determined as follows: (1) if the Common Stock is listed
on a national securities exchange or admitted to unlisted trading privileges on
such exchange or listed for trading on the Nasdaq Stock Market, the Fair Market
Value shall be the average of the last reported sale prices of the Common Stock
on such exchange or system for the twenty (20) business days ending on the last
business day prior to the date for which the determination is being made; or (2)
if the Common Stock is not so listed or admitted to unlisted trading privileges,
the Fair Market Value shall be the average of the last reported bid and asked
prices reported by the National Quotation Bureau, Inc. for the twenty (20)
business days ending on the last business day prior to the date for which the
determination is being made; or (3) if the Common Stock is not so listed or
admitted to unlisted trading privileges and bid and asked prices are not so
reported, the Fair Market Value shall be an amount, not less than book value
thereof as at the end of the most recent fiscal quarter of the Company ending
prior to the Exchange Date, determined in such reasonable manner as may be
prescribed by the Board of Directors of the Company.

     2.   RESERVATION OF SHARES.  The Company shall at all times reserve for
issuance and/or delivery upon exercise of this Warrant such number of shares of
its Common Stock as shall be required for issuance and delivery upon exercise of
this Warrant.

     3.   FRACTIONAL SHARES.  No fractional shares of Common Stock shall be
issued upon the exercise of this Warrant.  With respect to any fraction of a
share called for upon any exercise hereof, the Company shall pay to the Holder
an amount in cash equal to such fraction multiplied by the Fair Market Value of
a share of Common Stock.

     4.   ANTIDILUTION PROVISIONS.  In the event the Common Stock is changed by
reason of a stock split, reverse stock split, stock dividend or recapitalization
or is converted into or exchanged for other securities as a result of a merger,
consolidation or reorganization in which the Company is the surviving
corporation, appropriate adjustments shall be made in the terms of this Warrant,
or additional warrants shall be granted to the Holder as shall be equitable and
appropriate, or an adjustment in the number and class of shares allocated to,
and the Exercise Price of, this Warrant shall likewise be made.

     5.   CERTAIN EXTRAORDINARY TRANSACTIONS.  In the event the Common Stock is

                                       2
<PAGE>

exchanged for securities, cash or other property of any other corporation or
entity as the result of a reorganization, merger or consolidation in which the
Company is not the surviving corporation, the dissolution or liquidation of the
Company, or the sale of all or substantially all the assets of the Company, the
Board of Directors of the Company or the board of directors of any successor
corporation or entity may, in its discretion, as to the unexercised portion of
this Warrant, (a) provide for payment of an amount equal to the excess of the
fair market value of the Warrant Shares, as determined by the Board of Directors
of the Company or such board, over the Exercise Price of such Warrant Shares as
of the date of the transaction, in exchange for the surrender of the right to
exercise this Warrant, or (b) provide for the assumption of this Warrant, or the
substitution therefor of new warrants, by the successor corporation or entity.

     6.   LOSS OF WARRANT.  Upon receipt by the Company of evidence satisfactory
to it of the loss, theft, destruction or mutilation of this Warrant, and (in the
case of loss, theft or destruction) of reasonably satisfactory indemnification,
and upon surrender and cancellation of this Warrant, if mutilated, the Company
will execute and deliver a new warrant of like tenor and date.

     7.   NO RIGHTS AS STOCKHOLDER.  The Holder shall not, as holder of this
Warrant, be entitled to vote, if applicable, or to receive dividends or to be
deemed the holder of Common Stock that may at any time be issuable upon exercise
of this Warrant for any purpose whatsoever, nor shall anything contained herein
be construed to confer upon the Holder, as such, any of the rights of a
stockholder of the Company or, if applicable, any right to vote for the election
of directors or upon any matter submitted to stockholders at any meeting
thereof, or to give or withhold consent to any corporate action (whether upon
any recapitalization, issue or reclassification of stock, change of par value or
change of stock to no par value, consolidation, merger or conveyance or
otherwise), or to receive notice of meetings, or to receive dividends or
subscription rights, until such holder shall have exercised the Warrant and been
issued the Warrant Shares in accordance with the provisions hereof.

     8.   NON-TRANSFERABILITY.  Neither this Warrant nor any Warrant Shares
shall be registered under the Securities Act of 1933, as amended, and applicable
state securities laws.  Therefore, the Company shall require, as a condition of
allowing the transfer or exchange of this Warrant or such Warrant Shares, that
the Holder of this Warrant or such Warrant Shares, as the case may be, furnish
to the Company an opinion of counsel reasonably acceptable to the Company to the
effect that such transfer or exchange will be exempt from the registration and
prospectus delivery requirements under the Securities Act of 1933, as amended,
and applicable state securities laws.  The certificates evidencing the Warrant
Shares shall bear a legend to the effect that the Warrant Shares evidenced by
such certificate have not been registered under the Securities Act of 1933, as
amended, and applicable state securities laws and are, therefore, subject to
restrictions on transfer.

     9.   INVESTMENT REPRESENTATIONS AND WARRANTIES.  The Holder hereby
represents and warrants to the Company that (a) it has knowledge and experience
in financial and business matters sufficient to enable it to evaluate the merits
and risks of an investment in the Company; (b) it has assets sufficient to
enable it to bear the economic risk of its investment in this Warrant and the
Warrant Shares and is an "accredited investor" as defined in Rule 501 under the
Securities Act of 1933, as amended; (c) it is acquiring this Warrant and, upon
exercise, will acquire the Warrant Shares, for its own account, and not with a
view to, or for sale in connection with, any distribution thereof; (d) it or its
representatives have received from the Company such information with respect to
the Company as it has deemed necessary and relevant in connection with this
Warrant and the Warrant Shares and it has had the

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opportunity, directly or through such representatives, to ask questions of and
receive answers from persons acting on behalf of the Company necessary to verify
the information so obtained; and (e) it and its officers, directors, employees
and agents have not employed any broker or finder or incurred any liability for
any brokerage or finder's fees or commissions or similar payments in connection
with this Warrant and the Warrant Shares.

     10.  GOVERNING LAW.   This Agreement and all amendments, modifications,
alterations, or supplements hereto shall be construed under and governed by the
laws of the State of New Jersey and the United States of America, without regard
to the principles of conflicts of law thereof.

     11.  MISCELLANEOUS.  Except as provided in Sections 4 and 5 hereof, this
Warrant and any term hereof may be changed, waived, discharged or terminated
only by an instrument in writing signed by the party against which enforcement
of such change, waiver, discharge or termination is sought.  The headings in
this Warrant are for purposes of reference only and shall not limit or otherwise
affect any of the terms hereof.  The invalidity or unenforceability of any
provision hereof shall in no way affect the validity or enforceability of any
other provision.

     12.  EXPIRATION.  The right to exercise this Warrant shall expire at 5:00
P.M. Eastern Standard Time on December 23, 2006.

     This Warrant is executed as of the date and year first written above.

Witness:                                ORAPHARMA, INC.

                                        By: /s/ Michael Kishbauch
---------------------------                ----------------------------
                                           Michael Kishbauch, President

                                       4
<PAGE>

                              FORM OF SUBSCRIPTION
                   (To be signed only on exercise of Warrant)

TO: OraPharma, Inc.

     The undersigned, the holder of the within Warrant, hereby irrevocably
elects to exercise this Warrant for, and to purchase thereunder _______ shares
of Common Stock, $.001 par value per share, of OraPharma, Inc. and herewith
makes payment of $__________ therefor, and requests that the certificates for
such shares be issued in the name of, and delivered to the undersigned at
_____________________________.

Dated:                        _____________________________________________
                              (Signature must conform to name of holder as
                              specified on the face of the Warrant)

                              __________________________________
                                          (Address)

                              __________________________________

                                       5

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