Document:

Exhibit 10.1

                       SIXTH AMENDMENT TO CREDIT AGREEMENT

     THIS SIXTH AMENDMENT TO CREDIT  AGREEMENT (this  "Amendment"),  dated as of
April 3, 2007,  is by and among  CHATTEM,  INC.,  a Tennessee  corporation  (the
"Borrower"),  each  of the  Borrower's  Domestic  Subsidiaries  (individually  a
"Guarantor"  and  collectively  with the Borrower,  the "Credit  Parties"),  the
Persons  identified as lenders on the signature pages hereto (the "Lenders") and
BANK OF AMERICA, N.A., as agent for the Lenders (in such capacity, the "Agent").

                               W I T N E S S E T H

     WHEREAS, the Credit Parties, the Lenders, and the Agent are parties to that
certain Credit  Agreement dated as of February 26, 2004 (as amended from time to
time, the "Credit Agreement");

     WHEREAS,  the  Borrower  has  requested  that the Lenders  amend the Credit
Agreement; and

     WHEREAS, the Lenders have agreed to amend the Credit Agreement on the terms
and conditions hereinafter set forth.

     NOW, THEREFORE,  in consideration of the agreements  hereinafter set forth,
and for other good and valuable consideration, the receipt and adequacy of which
are hereby acknowledged, the parties hereto agree as follows:

                                     PART I
                                   DEFINITIONS

     Unless otherwise  defined herein or the context otherwise  requires,  terms
used in this Amendment,  including its preamble and recitals,  have the meanings
provided in the Credit Agreement.

                                     PART II
                         AMENDMENTS TO CREDIT AGREEMENT

     SUBPART 2.1 The  following  definitions  are hereby added to Section 1.1 of
the Credit Agreement in the appropriate alphabetical order to read as follows:

               (a) "Additional Indebtedness" means the unsecured Indebtedness of
          the Borrower  (a) the  principal of which by its terms is not required
          to be repaid,  in whole or in part,  before six months  after the Term
          Loan  Maturity  Date,  and (b)  which is  issued  pursuant  to  credit
          documents  having  covenants  and events of  default  that are no more
          restrictive than the covenants and events of default  contained in the
          Credit Documents.

               (b) "Sixth Amendment Effective Date" means April 3, 2007.
<PAGE>

     SUBPART 2.2 The pricing grid in the definition of  "Applicable  Percentage"
in Section 1.1 of the Credit Agreement is hereby amended to read as follows:

<TABLE>
<CAPTION>

============= ==================== ===================== ================ ==================

                                        Applicable
                                      Percentage For       Applicable
                                     Eurodollar Loans    Percentage For      Applicable
  Pricing          Leverage           and Letter of         Base Rate      Percentage for
   Level             Ratio              Credit Fee            Loans          Unused Fees
------------- -------------------- --------------------- ---------------- ------------------

<S>               <C>               <C>                <C>               <C>
     I           <1.50 to 1.0             0.875%             0.000%            0.200%
                 -
------------- -------------------- --------------------- ---------------- ------------------
     II       >1.50 to 1.0 but <          1.000%             0.000%            0.250%
                               -
                  2.50 to 1.0
------------- -------------------- --------------------- ---------------- ------------------
    III          > 2.50 to 1.0            1.250%             0.000%            0.300%
               but < 3.50 to 1.0
                   -
------------- -------------------- --------------------- ---------------- ------------------
     IV          > 3.50 to 1.0            1.500%             0.000%            0.350%
============= ==================== ===================== ================ ==================
</TABLE>

     SUBPART 2.3 The  following  three  sentences are hereby added at the end of
the definition of "Applicable Percentage" in Section 1.1 of the Credit Agreement
to read as follows:

               For the avoidance of doubt,  the Applicable  Percentage in effect
               from the Fifth Amendment Effective Date until the Sixth Amendment
               Effective Date was determined in accordance  with Pricing Level V
               in the definition of  "Applicable  Percentage" in effect prior to
               the Sixth Amendment Effective Date. The Applicable  Percentage in
               effect from the Sixth Amendment  Effective Date through the first
               Business  Day  immediately   following  the  date  the  officer's
               certificate  is delivered  pursuant to Section  7.1(c)(i) for the
               fiscal quarter ending May 31, 2007 shall be determined based upon
               Pricing  Level  IV.  Notwithstanding  anything  to  the  contrary
               contained in this definition, the determination of the Applicable
               Percentage  for any period shall be subject to the  provisions of
               Section 3.6(c).

     SUBPART 2.4 The following new clause (v) is hereby added to the  definition
of  "Change  of  Control"  in Section  1.1 of the  Credit  Agreement  to read as
follows:

          (v)  the occurrence of a "Change of Control" (or any comparable  term)
               under,  and  as  defined  in,  the  documentation  governing  any
               Additional Indebtedness.

     SUBPART  2.5 The  definition  of "Equity  Issuance"  in Section  1.1 of the
Credit Agreement is hereby amended to read as follows:

               "Equity  Issuance"  means any  issuance  by the  Borrower  to any
          Person of shares of its Capital Stock,  other than (a) any issuance of
          any shares of its Capital Stock pursuant to the exercise of options or
          warrants,  (b)  any  shares  of  its  Capital  Stock  pursuant  to the
          conversion of any debt securities (including the Convertible Notes and
          any  Additional  Indebtedness)  to equity and (c) any  issuance by the
          Borrower of shares of its Capital  Stock to  employees  and  directors
          pursuant to employees or directors stock plans.

     SUBPART  2.6 The  definition  of "Pro Forma  Basis" in  Section  1.1 of the
Credit Agreement is hereby amended to read as follows:

               "Pro  Forma  Basis"  means,  in  connection  with  any  Permitted
          Acquisition,  any Asset Disposition (including any contemporaneous pro
          forma  application  of the net  proceeds  therefrom),  any  Restricted
          Payment  permitted  by Section 8.7,  any  repayment  of the  principal
          amount  of  the  Convertible  Notes  or  any  Additional  Indebtedness
          permitted  by  Section  8.10,  any  prepayment  of  Subordinated  Debt
          pursuant to Section 8.11 or any incurrence of Additional Indebtedness,
          that such  transaction  shall be deemed to have  occurred on the first
          day  of  the  twelve  month  period  ending  on  the  last  day of the
          Borrower's  most  recently  completed  fiscal  quarter  for  which the
          Borrower has delivered the officer's  certificate  pursuant to Section
          7.1(c).
<PAGE>

     SUBPART 2.7 The following new subsection (c) is hereby added to Section 3.6
of the Credit Agreement to read as follows:

               (c) If, as a result of any restatement of or other  adjustment to
          the financial  statements of the Borrower or for any other reason, the
          Borrower  or the  Lenders  determine  that (i) the  Leverage  Ratio as
          calculated by the Borrower as of any  applicable  date was  inaccurate
          and  (ii) a  proper  calculation  of the  Leverage  Ratio  would  have
          resulted  in  higher  pricing  for such  period,  the  Borrower  shall
          immediately and retroactively be obligated to pay to the Agent for the
          account of the  applicable  Lenders,  promptly  on demand by the Agent
          (or, after the occurrence of an actual or deemed entry of an order for
          relief with respect to the Borrower under the  Bankruptcy  Code of the
          United  States,  automatically  and  without  further  action  by  the
          Administrative  Agent,  any Lender or the Issuing  Lender),  an amount
          equal to the excess of the  amount of  interest  and fees that  should
          have been paid for such period  over the amount of  interest  and fees
          actually  paid for such  period.  This  paragraph  shall not limit the
          rights of the Agent, any Lender or the Issuing Lender, as the case may
          be, under Section  2.2(c)(iii),  3.4(b) or 3.1 or under Section 9. The
          Borrower's   obligations   under  this  paragraph  shall  survive  the
          termination of the  Commitments  and the repayment of all other Credit
          Party Obligations hereunder.

     SUBPART 2.8 Section  8.1(i) of the Credit  Agreement  is hereby  amended to
read as follows:

               (i)(a)  Indebtedness of the Borrower under the Convertible  Notes
          in an  aggregate  principal  amount  not to exceed  $125,000,000,  (b)
          Additional Indebtedness of the Borrower incurred prior to the delivery
          of the financial  statements required by Section 7.1(b) for the fiscal
          period  ending May 31, 2007 in an  aggregate  principal  amount not to
          exceed  $100,000,000;  provided,  that no  Default or Event of Default
          exists  immediately before or after giving effect to the incurrence of
          any such Additional  Indebtedness  and (c) Additional  Indebtedness of
          the Borrower  incurred after the delivery of the financial  statements
          required by Section  7.1(b) for the fiscal period ending May 31, 2007;
          provided,  that (I) no Default or Event of Default exists  immediately
          before or after giving effect to the incurrence of any such Additional
          Indebtedness and (II) the Borrower shall have provided the Agent a Pro
          Forma Compliance Certificate demonstrating that after giving effect to
          the incurrence of any such  Additional  Indebtedness  pursuant to this
          clause  (c)  on a Pro  Forma  Basis,  the  Credit  Parties  and  their
          Subsidiaries  are in compliance  with all the financial  covenants set
          forth in Section 7.12; and

     SUBPART 2.9 Subclause (c) of Section 8.10 of the Credit Agreement is hereby
amended to read as follows:

               (c) make any repayment in cash for the  Convertible  Notes or any
          Additional   Indebtedness  (or  otherwise  make  any  payment  on  the
          principal of any  Convertible  Notes or any  Additional  Indebtedness)
          unless (i) prior to any such  repayment,  the Borrower has  Sufficient
          Liquidity (as defined below),  (ii) prior to any such  repayment,  the
          Borrower shall deliver to the Agent a Pro Forma Compliance Certificate
          demonstrating  that after  giving  effect to any such payment on a Pro
          Forma Basis, the Credit Parties and their Subsidiaries would have been
          in compliance  with all the  financial  covenants set forth in Section
          7.12 and (ii) before and after giving effect to any such repayment, no
          Default or Event of Default shall have occurred and be continuing.
<PAGE>

     SUBPART 2.10 The last paragraph of Section 8.10 of the Credit  Agreement is
hereby amended to read as follows:

               For purposes hereof,  "Sufficient  Liquidity" means cash and Cash
          Equivalents  (including,  without  limitation,  availability under the
          Revolving  Committed  Amount) in an aggregate  amount equal to 125% of
          the sum of the principal amount of the Convertible Notes or Additional
          Indebtedness contemplated to be paid by the Borrower in cash.

     SUBPART  2.11  Subsection  (n) of Section  9.1 of the Credit  Agreement  is
hereby amended to read as follows:

          (n)  Convertible  Notes.  There shall occur an "Event of Default"  (or
               any  comparable   term)  under,   and  as  defined  in,  (i)  the
               Convertible Indenture and/or (ii) any documentation governing any
               Additional Indebtedness.

                                    PART III
                           CONDITIONS TO EFFECTIVENESS

     This  Amendment  shall be and become  effective  upon  satisfaction  of the
following conditions precedent:

               (a) Receipt by the Agent of  counterparts  of this Amendment duly
          executed by the Borrower,  the Guarantors,  the Required Lenders, each
          Lender with a Revolving Commitment and the Agent; and

               (b)  Receipt  by the Agent for the  account  of each  Lender  who
          consents to this  Amendment an amendment  fee of 5 basis points on the
          aggregate  amount of each such Lender's (i) Revolving  Commitment  and
          (ii) portion of the Term Loan outstanding.

                                     PART IV
                                  MISCELLANEOUS

     SUBPART  4.1  Representations  and  Warranties.  Each Credit  Party  hereby
represents  and  warrants  to the Agent and the  Lenders  that (a) no Default or
Event of Default exists on and as of the date hereof,  (b) each Credit Party has
the requisite corporate power and authority to execute, deliver and perform this
Amendment and (c) the  representations  and warranties set forth in Section 6 of
the Credit  Agreement  are true and correct in all  material  respects as of the
date hereof (except for those which expressly  relate to an earlier date).  Each
Credit Party acknowledges and confirms that the Borrower's  obligations to repay
the outstanding  principal amount of the Loans are unconditional and not subject
to any offsets, defenses or counterclaims.

     SUBPART 4.2 Acknowledgment. Each Guarantor hereby acknowledges and consents
to all of the  terms and  conditions  of this  Amendment  and  agrees  that this
Amendment  does not operate to reduce or discharge the  Guarantors'  obligations
under the Credit Agreement or the other Credit Documents.

     SUBPART 4.3  Cross-References.  References in this Amendment to any Part or
Subpart  are,  unless  otherwise  specified,  to such  Part or  Subpart  of this
Amendment.
<PAGE>

     SUBPART 4.4 Credit  Document.  This  Amendment  shall  constitute  a Credit
Document under the terms of the Credit Agreement.

     SUBPART 4.5  References in Other Credit  Documents.  All  references to the
Credit Agreement in each of the Credit Documents shall hereafter mean the Credit
Agreement as amended by this Amendment. Except as specifically amended hereby or
otherwise  agreed,  the Credit  Agreement is hereby  ratified and  confirmed and
shall remain in full force and effect according to its terms.

     SUBPART 4.6  Counterparts/Telecopy.  This  Amendment may be executed by the
parties hereto in several  counterparts,  each of which shall be deemed to be an
original  and all of  which  shall  constitute  together  but  one and the  same
agreement. Delivery of executed counterparts of this Amendment by telecopy shall
be  effective  as an original  and shall  constitute  a  representation  that an
original shall be delivered.

     SUBPART 4.7 Governing Law. THIS AMENDMENT  SHALL BE DEEMED TO BE A CONTRACT
MADE UNDER AND GOVERNED BY THE INTERNAL LAWS OF THE STATE OF NEW YORK.

     SUBPART 4.8  Successors and Assigns.  This Amendment  shall be binding upon
and inure to the benefit of the parties hereto and their  respective  successors
and assigns.

                  [remainder of page intentionally left blank]

<PAGE>

         IN WITNESS WHEREOF the Borrower, the Guarantors and the Lenders have
caused this Amendment to be duly executed on the date first above written.

BORROWER:

                                CHATTEM, INC.,
                                a Tennessee corporation

                                By: /s/ Robert E. Bosworth
                                ----------------------------------------------
                                Name: Robert E. Bosworth
                                Title: President and Chief Operating Officer

GUARANTORS:                     SIGNAL INVESTMENT & MANAGEMENT CO.,

                                a Delaware corporation

                                By: /s/ Robert E. Bosworth
                                ----------------------------------------------
                                Name: Robert E. Bosworth
                                Title: President

                                SUNDEX, LLC,
                                a Tennessee limited liability company

                                By: /s/ Robert E. Bosworth
                                ----------------------------------------------
                                Name: Robert E. Bosworth
                                Title: President

                                CHATTEM (CANADA) HOLDINGS, INC.,
                                a Delaware corporation

                                By: /s/ Robert E. Bosworth
                                ----------------------------------------------
                                Name: Robert E. Bosworth
                                Title: President

<PAGE>

AGENT:                          BANK OF AMERICA, N.A.,
                                in its capacity as Agent

                                By: /s/ Kristine Thennes
                                ----------------------------------------------
                                Name: Kristine Thennes
                                Title: Vice President

LENDERS:                        BANK OF AMERICA, N.A.,
                                in its capacity as a Lender

                                By: /s/ John M. Hall
                                ----------------------------------------------
                                Name: John M. Hall
                                Title: Senior Vice President

                                SUNTRUST BANK

                                By: /s/ Kap Yarbrough
                                ----------------------------------------------
                                Name: Kap Yarbrough
                                Title: Vice President

                                BRANCH BANKING AND TRUST COMPANY

                                By: /s/ R. Andrew Beam
                                ----------------------------------------------
                                Name: R. Andrew Beam
                                Title: Senior Vice President

                                NATIONAL CITY BANK

                                By: /s/ Kevin L. Anderson
                                ----------------------------------------------
                                Name: Kevin L. Anderson
                                Title: Senior Vice President

                                WACHOVIA BANK, NATIONAL ASSOCIATION

                                By: /s/ Susan T. Gallagher
                                ----------------------------------------------
                                Name: Susan T. Gallagher
                                Title: Vice President

<PAGE>

                                280 FUNDING I

                                By: /s/ Matthew Quigley
                                ----------------------------------------------
                                Name: Matthew Quigley
                                Title: Authorized Signatory

                                ACA CLO 2007 - 1, LIMITED

                                By: ACA Management, LLC,
                                as Investment Advisor

                                By: /s/ Vincent Ingato
                                ----------------------------------------------
                                Name: Vincent Ingato
                                Title: Managing Director

                                AIB DEBT MANAGEMENT, LIMITED

                                By: /s/ Joseph Augustini
                                ----------------------------------------------
                                Name: Joseph Augustini
                                Title: Senior Vice President
                                Investment Advisor to AIB Debt Management,
                                Limited

                                By: /s/ Gregory J. Wiske
                                ----------------------------------------------
                                Name: Gregory J. Wiske
                                Title: Senior Vice President,
                                Investment Advisor to AIB Debt Management,
                                Limited

                                AIM FLOATING RATE FUND

                                By: INVESCO Senior Secured Management, Inc.,
                                as Sub-Advisor

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

                                ALLSTATE LIFE INSURANCE COMPANY

                                By: /s/ Chris Goergen
                                ----------------------------------------------
                                Name: Chris Goergen
                                Title: Authorized Signatory

                                By: /s/ Breeze Ferrell
                                ----------------------------------------------
                                Name: Breeze Ferrell
                                Title: Authorized Signatory

<PAGE>

                                ALZETTE EUROPEAN CLO S.A.

                                By: INVESCO Senior Secured Management, Inc.,
                                as Collateral Manager

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

                                ARCHIMEDES FUNDING IV (CAYMAN), LTD.

                                By: West Gate Horizons Advisors LLC,
                                as Collateral Manager

                                By: /s/ Cheryl Wasilewski
                                ----------------------------------------------
                                Name: Cheryl Wasilewski
                                Title: Senior Credit Analyst

                                ARES LEVERAGED FINANCE GENERAL I

                                By: Ares CLO Management XI, L.P.

                                By: Ares CLO GP XI,
                                Its: General Partner

                                By: Ares Management LLC
                                Its: Manager

                                By: /s/ Seth J. Brufsky
                                ----------------------------------------------
                                Name: Seth J. Brufsky
                                Title: Vice President

                                ARES IIIR/IVR CLO LTD.

                                By: Ares CLO Management III/IVR, L.P.
                                Investment Advisor

                                By: Ares CLO GP IIIR/IVR, LLC
                                Its: Managing Member

                                By: /s/ Seth J. Brufsky
                                ----------------------------------------------
                                Name: Seth J. Brufsky
                                Title: Vice President

<PAGE>

                                CONFLUENT 2 LIMITED

                                By: Ares Private Account Management I, L.P.,
                                as Sub-Manager

                                By: Ares Private Account Management I GP, LLC,
                                as General Partner

                                By: Ares Management LLC
                                as Manager

                                By: /s/ Seth J. Brufsky
                                ----------------------------------------------
                                Name: Seth J. Brufsky
                                Title: Vice President

                                ATLAS LOAN FUNDING (CENT I) LLC

                                By: RiverSource Investments, LLC,
                                Attorney in Fact

                                By: /s/ Traci D. Garcia
                                ----------------------------------------------
                                Name: Traci D. Garcia
                                Title: Sr. Business Analyst

                                ATLAS LOAN FUNDING (HARTFORD) LLC

                                By: Atlas Capital Funding, Ltd.

                                By: Structured Asset Investors, LLC,
                                Its: Investment Manager

                                By: /s/ Diana M. Himes
                                ----------------------------------------------
                                Name: Diana M. Himes
                                Title: Vice President

                                ATLAS LOAN FUNDING (NAVIGATOR) LLC

                                By: Atlas Capital Funding, Ltd.

                                By: Structured Asset Investors, LLC,
                                Its: Investment Manager

                                By: /s/ Diana M. Himes
                                ----------------------------------------------
                                Name: Diana M. Himes
                                Title: Vice President

<PAGE>

                                ATRIUM V

                                By: /s/ Linda R. Karn
                                ----------------------------------------------
                                Name: Linda R. Karn
                                Title: Authorized Signatory

                                AVALON CAPITAL LTD. 3

                                By: INVESCO Senior Secured Management, Inc.,
                                as Asset Manager

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

                                AVENUE CLO V, LTD.

                                By: /s/ Richard D'addario
                                ----------------------------------------------
                                Name: Richard D'addario
                                Title: Senior Portfolio Manager

                                BALLYROCK CLO 2006-1 LTD

                                By: BALLYROK Investment Advisors LLC,
                                as Collateral Manager

                                By: /s/ Lisa Rymut
                                ----------------------------------------------
                                Name: Lisa Rymut
                                Title: Assistant Treasurer

                                BALLYROCK CLO II LIMITED

                                By: BALLYROK Investment Advisors LLC,
                                as Collateral Manager

                                By: /s/ Lisa Rymut
                                ----------------------------------------------
                                Name: Lisa Rymut
                                Title: Assistant Treasurer

<PAGE>

                                BANK OF AMERICA, N.A.

                                By: /s/ Michael S. Roof
                                ----------------------------------------------
                                Name: Michael S. Roof
                                Title: Vice President

                                BEAR STEARNS LOAN TRUST

                                By: Bear Stearns Asset Management, Inc.,
                                as its attorney-in-fact

                                By: /s/ Niell Rosenzweig
                                ----------------------------------------------
                                Name: Niell Rosenzweig
                                Title: Managing Director

                                BELHURST CLO LTD.

                                By: INVESCO Senior Secured Management, Inc.,
                                as Collateral Manager

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

                                BLACK ROCK SENIOR INCOME SERIES
                                BLACK ROCK SENIOR INCOME SERIES II
                                BLACKROCK SENIOR INCOME SERIES IV
                                LONGHORN CDO III, LTD
                                MAGNETITE V CLO, LIMITED

                                By: /s/ Tony Heyman
                                ----------------------------------------------
                                Name: Tony Heyman
                                Title: Authorized Signatory

<PAGE>

                                BLF WAREHOUSE I, LTD.

                                By: Octagon Credit Investors, LLC,
                                as Collateral Manager

                                By: /s/ Andrew D. Gordon
                                ----------------------------------------------
                                Name: Andrew D. Gordon
                                Title: Senior Portfolio Manager

                                CASTLE GARDEN FUNDING

                                By: /s/ Linda R. Karn
                                ----------------------------------------------
                                Name: Linda R. Karn
                                Title: Authorized Signatory

                                CENT CDO 12 LIMITED

                                By: RiverSource Investments, LLC,
                                as Collateral Manager

                                By: /s/ Traci D. Garcia
                                ----------------------------------------------
                                Name: Traci D. Garcia
                                Title: Sr. Business Analyst

                                CENT CDO 14 LIMITED

                                By: RiverSource Investments, LLC,
                                as Collateral Manager

                                By: /s/ Traci D. Garcia
                                ----------------------------------------------
                                Name: Traci D. Garcia
                                Title: Sr. Business Analyst

                                CENTURION CDO III, LIMITED

                                By: RiverSource Investments, LLC,
                                as Collateral Manager

                                By: /s/ Traci D. Garcia
                                ----------------------------------------------
                                Name: Traci D. Garcia
                                Title: Sr. Business Analyst

<PAGE>

                                CHAMPLAIN CLO, LTD.

                                By: INVESCO Senior Secured Management, Inc.,
                                as Collateral Manager

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

                                CHARTER VIEW PORTFOLIO

                                By: INVESCO Senior Secured Management, Inc.,
                                as Investment Advisor

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

                                CHATHAM LIGHT III CLO, LTD

                                By: Sankaty Advisors, LLC,
                                as Collateral Manager

                                By: /s/ Alan K. Halfenger
                                ----------------------------------------------
                                Name: Alan K. Halfenger
                                Title: Chief Compliance Officer and Assistant

                                CIFC FUNDING 2006-II, LTD.
                                CIFC FUNDING 2007-I, LTD

                                By: /s/ Nga Tran
                                ----------------------------------------------
                                Name: Nga Tran
                                Title: Head of Underwriting

<PAGE>

                                CONFLUENT 3 LIMITED

                                By: Morgan Stanley Investment Management, Inc.
                                as Investment Manager

                                By: /s/ Jinny Kim
                                ----------------------------------------------
                                Name: Jinny Kim
                                Title: Executive Director

                                DIVERSIFIED CREDIT PORTFOLIO LTD.

                                By: INVESCO Senior Secured Management, Inc.,
                                as Investment Advisor

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

                                EATON VANCE CDO VIII, LTD.

                                By: Eaton Vance Management,
                                as Investment Advisor

                                By: /s/ Scott N. Page
                                ----------------------------------------------
                                Name: Scott N. Page
                                Title: Vice President

                                EATON VANCE CDO XI, LTD

                                By: Eaton Vance Management,
                                as Investment Advisor

                                By: /s/ Scott N. Page
                                ----------------------------------------------
                                Name: Scott N. Page
                                Title: Vice President

<PAGE>

                                EATON VANCE INSTITUTIONAL SENIOR LOAN FUND

                                By: Eaton Vance Management,
                                as Investment Advisor

                                By: /s/ Scott N. Page
                                ----------------------------------------------
                                Name: Scott N. Page
                                Title: Vice President

                                EATON VANCE VARIABLE LEVERAGE FUND, LTD.

                                By: Eaton Vance Management,
                                as Investment Advisor

                                By: /s/ Scott N. Page
                                ----------------------------------------------
                                Name: Scott N. Page
                                Title: Vice President

                                EATON VANCE FLOATING-RATE INCOME FUND

                                By: Eaton Vance Management,
                                as Investment Advisor

                                By: /s/ Scott N. Page
                                ----------------------------------------------
                                Name: Scott N. Page
                                Title: Vice President

                                FIDELITY ADVISOR SERIES II: FIDELITY ADVISOR
                                FLOATING RATE HIGH INCOME FUND

                                By: /s/ Peter L. Lydecker
                                ----------------------------------------------
                                Name: Peter L. Lydecker
                                Title: Assistant Treasurer

<PAGE>

                                FRANKLIN CLO IV, LIMITED

                                By: /s/ David Ardini
                                ----------------------------------------------
                                Name: David Ardini
                                Title: Vice President

                                FRANKLIN FLOATING RATE DAILY ACCESS FUND

                                By: /s/ Madeline Lam
                                ----------------------------------------------
                                Name: Madeline Lam
                                Title: Asst. Vice President

                                FRANKLIN FLOATING RATE MASTER SERIES

                                By: /s/ Madeline Lam
                                ----------------------------------------------
                                Name: Madeline Lam
                                Title: Asst. Vice President

                                GALAXY VI CLO, LTD

                                By: AIG Global Investment Corp.,
                                its Collateral Manager

                                By: /s/ Steven S. Oh
                                ----------------------------------------------
                                Name: Steven S. Oh
                                Title: Managing Director

                                GALAXY IX CLO, LTD

                                By: AIG Global Investment Corp.,
                                its Collateral Manager

                                By: /s/ Steven S. Oh
                                ----------------------------------------------
                                Name: Steven S. Oh
                                Title: Managing Director

<PAGE>

                                GALE FORCE 3 CLO, LTD.

                                By: GSO Capital Partners LP,
                                as Collateral Manager

                                By: /s/ Melissa Marano
                                ----------------------------------------------
                                Name: Melissa Marano
                                Title: Authorized Signatory

                                GALLATIN CLO III 2007-1, LTD.

                                By: Bear Stearns Asset Management Inc.,
                                as its Collateral Manager

                                By: /s/ Jonathan Berg
                                ----------------------------------------------
                                Name: Jonathan Berg
                                Title: Associate Director

                                GANNETT PEAK CLO I, LTD.

                                By: McDonnell Investment Management, LLC,
                                as Investment Manager

                                By: /s/ Kathleen A. Zarn
                                ----------------------------------------------
                                Name: Kathleen A. Zarn
                                Title: Vice President

                                GENERAL ELECTRIC CAPITAL CORPORATION

                                By: /s/ Alison P. Trapp
                                ----------------------------------------------
                                Name: Alison P. Trapp
                                Title: Duly Authorized Signatory

                                GENERAL ELECTRIC PENSION TRUST

                                By: GE Asset Management Inc.,
                                as Collateral Manager

                                By: /s/ John Campos
                                ----------------------------------------------
                                Name: John Campos
                                Title: Authorized Signatory

                                GMAM GROUP PENSION TRUST I

                                By: State Street Bank & Trust Company as Trust
                                for GMAM Group Pension Trust I

                                By: /s/ Name Illegible
                                ----------------------------------------------
                                Name: Name Illegible
                                Title: Assistant Vice President

                                GRAND CENTRAL ASSET TRUST, PFV SERIES

                                By: /s/ Jason Muelver
                                ----------------------------------------------
                                Name: Jason Muelver
                                Title: Attorney-in-fact

                                GSC PARTNERS CDO FUND IX, LIMITED

                                By: GSCP (NJ), L.P.,
                                as Collateral Manager

                                By: /s/ Tom Inglesby
                                ----------------------------------------------
                                Name: Tom Inglesby
                                Title: Authorized Signatory

                                GSC PARTNERS CDO FUND VIII, LIMITED

                                By: GSCP (NJ), L.P.,
                                as Collateral Manager

                                By: /s/ Tom Inglesby
                                Name: Tom Inglesby
                                ----------------------------------------------
                                Title: Authorized Signatory

                                GSO DOMESTIC CAPITAL FUNDING

                                By: GSO Capital Partners LP,
                                as Collateral Manager

                                By: /s/ Matthew Quigley
                                ----------------------------------------------
                                Name: Matthew Quigley
                                Title: Authorized Signatory
<PAGE>

                                GULF STREAM-NAVIGATOR LOAN FUND 2006 SEGREGATE

                                By: Gulf Stream Asset Management, LLC,
                                as Collateral Manager

                                By: /s/ Mark D. Abraham
                                ----------------------------------------------
                                Name: Mark D. Abraham
                                Title: Trader

                                GULF STREAM-RASHINBAN CLO 2006-1LTD

                                By: Gulf Stream Asset Management, LLC,
                                as Collateral Manager

                                By: /s/ Mark D. Abraham
                                ----------------------------------------------
                                Name: Mark D. Abraham
                                Title: Trader

                                IKB CAPITAL CORPORATION

                                By: /s/ David Snyder
                                ----------------------------------------------
                                Name: David Snyder
                                Title: President

                                HALCYON LOAN INVESTORS CLO II, LTD.

                                By: /s/ Aaron Goldberg
                                ----------------------------------------------
                                Name: Aaron Goldberg
                                Title: Chief Financial Officer

                                HALCYON STRUCTURED ASSET MANAGEMENT CLO I LTD.

                                By: /s/ Aaron Goldberg
                                ----------------------------------------------
                                Name: Aaron Goldberg
                                Title: Chief Financial Officer

<PAGE>

                                HAMLET II, LTD.

                                By: Octagon Credit Investors, LLC,
                                as Portfolio Manager

                                By: /s/ Andrew D. Gordon
                                ----------------------------------------------
                                Name: Andrew D. Gordon
                                Title: Senior Portfolio Manager

                                HARBOUR TOWN FUNDING LLC

                                By: /s/ M. Cristina Higgins
                                ----------------------------------------------
                                Name: M. Cristina Higgins
                                Title: Assistant Vice President

                                THE HARTFORD MUTUAL FUNDS, INC.,
                                on behalf of the Hartford Floating Rate Fund by
                                Hartford Investment Management Company,
                                its sub-advisor, as a lender

                                By: /s/ Michael A. Pineau
                                ----------------------------------------------
                                Name: Michael A. Pineau
                                Title: Vice President

                                HEWETT'S ISLAND CLO V, LTD.

                                By: CypressTree Investment Management Company,
                                as Portfolio Manager

                                By: /s/ Robert Weeden
                                Name: Robert Weeden
                                Title: Managing Director

                                HORSESHOE BEND SPIRET LOAN TRUST

                                By: /s/ Rachel L. Simpson
                                ----------------------------------------------
                                Name: Rachel L. Simpson
                                Title: Sr. Financial Services Officer
<PAGE>

                                KATONAH V, LTD.

                                By: INVESCO Senior Secured Management, Inc.,
                                as Investment Manager

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

                                KINGSLAND III, LTD.

                                By: Kingsland Capital Management, LLC,
                                as Manager

                                By: /s/ Vincent Sino
                                ----------------------------------------------
                                Name: Vincent Sino
                                Title: Manager

                                KINGSLAND IV, LTD.

                                By: Kingsland Capital Management, LLC,
                                as Manager

                                By: /s/ Vincent Sino
                                ----------------------------------------------
                                Name: Vincent Sino
                                Title: Manager

                                KZH SOLEIL-2 LLC

                                By: /s/ Dorian Herrera
                                ----------------------------------------------
                                Name: Dorian Herrera
                                Title: Authorized Agent

                                LA FUNDING LLC

                                By: /s/ M. Cristina Higgins
                                ----------------------------------------------
                                Name: M. Cristina Higgins
                                Title: Assistant Vice President

<PAGE>

                                LCM V LTD.

                                By: Lyon Capital Management LLC,
                                as Collateral Manager

                                By: /s/ Sophie A. Venon
                                ----------------------------------------------
                                Name: Sophie A. Venon
                                Title: Portfolio Manager

                                LCM VI LTD.

                                By: Lyon Capital Management LLC,
                                as Attorney-in-Fact

                                By: /s/ Sophie A. Venon
                                ----------------------------------------------
                                Name: Sophie A. Venon
                                Title: Portfolio Manager

                                LCM VII LTD.

                                By: Lyon Capital Management LLC,
                                as Attorney-in-Fact

                                By: /s/ Sophie A. Venon
                                ----------------------------------------------
                                Name: Sophie A. Venon
                                Title: Portfolio Manager

                                LIGHTPOINT CLO III
                                LIGHTPOINT CLO IV
                                MARQUETTE US/EUROPEAN CLO P.L.C.

                                By: /s/ Colin Donlan
                                ----------------------------------------------
                                Name: Colin Donlan
                                Title: Director

                                LIMEROCK CLO I

                                By: INVESCO Senior Secured Management, Inc.,
                                as Manager

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

<PAGE>

                                LOAN FUNDING IX LLC,
                                for itself or as agent for Corporate Loan Fund

                                By: INVESCO Senior Secured Management, Inc.,
                                as Portfolio Manager

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

                                MADISON PARK FUNDING II, LTD.

                                By: /s/ Linda R. Karn
                                ----------------------------------------------
                                Name: Linda R. Karn
                                Title: Authorized Signatory

                                MORGAN STANLEY PRIME INCOME TRUST

                                By: /s/ Jinny Kim
                                ----------------------------------------------
                                Name: Jinny Kim
                                Title: Executive Director

                                MOSELLE CLO S.A.

                                By: INVESCO Senior Secured Management, Inc.,
                                as Collateral Manager

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

                                MOUNTAIN VIEW CLO II, LTD.

                                By: Seix Advisors, a fixed income division of
                                Trusco Capital Management, Inc.,
                                as Collateral Manager

                                By: /s/ George Goudelias
                                ----------------------------------------------
                                Name: George Goudelias
                                Title: PM, Seix Advisor

<PAGE>

                                MSIM CRORON, LTD.

                                By: Morgan Stanley Investment Management, Inc.
                                as Collateral Manager

                                By: /s/ Jinny Kim
                                ----------------------------------------------
                                Name: Jinny Kim
                                Title: Executive Director

                                MSIM PECONIC BAY, LTD.

                                By: Morgan Stanley Investment Management, Inc.
                                as Interim Collateral Manager

                                By: /s/ Jinny Kim
                                ----------------------------------------------
                                Name: Jinny Kim
                                Title: Executive Director

                                NAUTIQUE FUNDING II LTD.

                                By: INVESCO Senior Secured Management, Inc,
                                as Collateral Manager

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

                                NAUTIQUE FUNDING LTD.

                                By: INVESCO Senior Secured Management, Inc,
                                as Collateral Manager

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

<PAGE>

                                NYLM FLATIRON CLO 2006-1 LTD.

                                By: New York Life Investment Management LLC,
                                as Collateral Manager and Attorney-in-Fact

                                By: /s/ F. Berthelet
                                ----------------------------------------------
                                Name: F. Berthelet
                                Title: Director

                                MAINSTAY VP FLOATING RATE PORTFOLIO,
                                a Series of Mainstay VP Series Fund,
                                Inc.

                                By: New York Life Investment Management LLC

                                By: /s/ F. Berthelet
                                ----------------------------------------------
                                Name: F. Berthelet
                                Title: Director

                                MAINSTAY FLOATING RATE FUND, a
                                Series of Eclipse Funds, Inc.

                                By: New York Life Investment Management LLC

                                By: /s/ F. Berthelet
                                ----------------------------------------------
                                Name: F. Berthelet
                                Title: Director

                                OCEAN TRAILS CLO II

                                By: West Gate Horizons Advisors LLC, as Manage

                                By: /s/ Cheryl Wasilewski
                                ----------------------------------------------
                                Name: Cheryl Wasilewski
                                Title: Senior Credit Analyst

<PAGE>

                                OCTAGON INVESTMENT PARTNERS XI, LTD.

                                By: Octagon Credit Investors, LLC,
                                as Collateral Manager

                                By: /s/ Andrew D. Gordon
                                ----------------------------------------------
                                Name: Andrew D. Gordon
                                Title: Senior Portfolio Manager

                                OSP FUNDING LLC

                                By: /s/ M. Cristina Higgins
                                ----------------------------------------------
                                Name: M. Cristina Higgins
                                Title: Assistant Vice President

                                PETRUSSE EUROPEAN CLO S.A.

                                By: INVESCO Senior Secured Management, Inc,
                                as Collateral Manager

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

                                PPM GRAYHAWK CLO, LTD.

                                By: PPM America, Inc.,
                                as Collateral Manager

                                By: /s/ David C. Wagner
                                ----------------------------------------------
                                Name: David C. Wagner
                                Title: Managing Director

                                PPM SHADOW CREEK FUNDING LLC

                                By: /s/ M. Cristina Higgins
                                ----------------------------------------------
                                Name: M. Cristina Higgins
                                Title: Assistant Vice President

<PAGE>

                                QUALCOMM GLOBAL TRADING, INC.

                                By: Morgan Stanley Investment Management, Inc.
                                as Investment Manager

                                By: /s/ Jinny Kim
                                ----------------------------------------------
                                Name: Jinny Kim
                                Title: Executive Director

                                RACE POINT IV CLO, LTD

                                By: Sankaty Advisors, LLC,
                                as Collateral Manager

                                By: /s/ Alan K. Halfenger
                                ----------------------------------------------
                                Name: Alan K. Halfenger
                                Title: Chief Compliance Officer and Assistant
                                Secretary

                                REGATTA II FUNDING LTD.

                                By: Citigroup Alternative Investments LLC,
                                Attorney-in-Fact

                                By: /s/ Melanie Hanlon
                                ----------------------------------------------
                                Name: Melanie Hanlon
                                Title: Director

                                RIVERSOURCE BOND SERIES, INC. -
                                RIVERSOURCE FLOATING RATE FUND

                                By: /s/ Yvonne E. Stevens
                                ----------------------------------------------
                                Name: Yvonne E. Stevens
                                Title: Assistant Vice President

                                SANKATY ADVISORS, LLC,
                                as Collateral Manager for Race Point CLO,
                                Limited, as Term Lender

                                By: /s/ Alan K. Halfenger
                                ----------------------------------------------
                                Name: Alan K. Halfenger
                                Title: Chief Compliance Officer and Assistant
                                Secretary

                                REGATTA FUNDING LTD.

                                By: Citigroup Alternative Investments LLC,
                                Attorney-in-Fact

                                By: /s/ Melanie Hanlon
                                ----------------------------------------------
                                Name: Melanie Hanlon
                                Title: Director

                                SAGAMORE CLO LTD.

                                By: INVESCO Senior Secured Management, Inc.,
                                as Collateral Manager

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

                                SANKATY HIGH YIELD PARTNERS, II, L.P.

                                By: /s/ Alan K. Halfenger
                                ----------------------------------------------
                                Name: Alan K. Halfenger
                                Title: Chief Compliance Officer and Assistant

                                SARATOGA CLO I, LIMITED

                                By: INVESCO Senior Secured Management, Inc.,
                                as the Asset Manager

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

                                SENIOR DEBT PORTFOLIO

                                By: Boston Management and Research,
                                as Investment Advisor

                                By: /s/ Scott N. Page
                                ----------------------------------------------
                                Name: Scott N. Page
                                Title: Vice President
<PAGE>

                                SEQUILS-CENTURION V, LTD.

                                By: RiverSource Investments, LLC,
                                as Collateral Manager

                                By: /s/ Traci Dawn Garcia
                                ----------------------------------------------
                                Name: Traci D. Garcia
                                Title: Sr. Business Analyst

                                STANFIELD DAYTONA CLO, LTD.

                                By: Stanfield Capital Partners, LLC,
                                as its Collateral Manager

                                By: /s/ Christopher E. Jansen
                                ----------------------------------------------
                                Name: Christopher E. Jansen
                                Title: Managing Partner

                                STANFIELD MCLAREN CLO, LTD.

                                By: Stanfield Capital Partners, LLC,
                                as its Collateral Manager

                                By: /s/ Christopher E. Jansen
                                ----------------------------------------------
                                Name: Christopher E. Jansen
                                Title: Managing Partner

                                STANFIELD QUATTRO CLO, LTD.

                                By: Stanfield Capital Partners, LLC,
                                as its Collateral Manager

                                By: /s/ Christopher E. Jansen
                                ----------------------------------------------
                                Name: Christopher E. Jansen
                                Title: Managing Partner

<PAGE>

                                SUNLIFE ASSURANCE COMPANY OF CANADA (US)

                                By: GSO Capital Partners LP,
                                as Sub-Advisor

                                By: /s/ Melissa Marano
                                ----------------------------------------------
                                Name: Melissa Marano
                                Title: Authorized Signatory

                                SYMPHONY CLO II

                                By: Symphony Asset Management LLC

                                By: /s/ Lenny Mason
                                ----------------------------------------------
                                Name: Lenny Mason
                                Title: Portfolio Manager

                                SYMPHONY CLO III

                                By: Symphony Asset Management LLC

                                By: /s/ Lenny Mason
                                ----------------------------------------------
                                Name: Lenny Mason
                                Title: Portfolio Manager

                                TAVITIAN FOUNDATION, INC.

                                By: Shenkman Capital Management, Inc.,
                                as Investment Manager

                                By: /s/ Richard H. Weinstein
                                ----------------------------------------------
                                Name: Richard H. Weinstein
                                Title: Executive Vice President

                                UNUM LIFE INSURANCE COMPANY
                                OF AMERICA

                                By: /s/ Ben S. Miller
                                ----------------------------------------------
                                Name: Ben S. Miller
                                Title: Vice President

<PAGE>

                                VAN KAMPEN SENIOR INCOME TRUST

                                By: Van Kampen Asset Management

                                By: /s/ Robert P. Drobny
                                ----------------------------------------------
                                Name: Robert P. Drobny
                                Title: Vice President

                                VAN KAMPEN SENIOR LOAN FUND

                                By: Van Kampen Asset Management

                                By: /s/ Robert P. Drobny
                                ----------------------------------------------
                                Name: Robert P. Drobny
                                Title: Vice President

                                VENTURE VII CDO LIMITED

                                By: MIX Asset Management LLC,
                                its investment advisor

                                By: /s/ Hans L. Christensen
                                ----------------------------------------------
                                Name: Hans L. Christensen
                                Title: Chief Investment Officer

                                VENTURE VIII WAREHOUSE

                                By: /s/ Hans L. Christensen
                                ----------------------------------------------
                                Name: Hans L. Christensen
                                Title: Chief Investment Officer

                                WASATCH CLO LTD.

                                By: INVESCO Senior Secured Management, Inc.,
                                as Portfolio Manager

                                By: /s/ Thomas Ewald
                                ----------------------------------------------
                                Name: Thomas Ewald
                                Title: Authorized Signatory

<PAGE>

                                WB LOAN FUNDING 8, LLC

                                By: /s/ Diana M. Himes
                                ----------------------------------------------
                                Name: Diane M. Himes
                                Title: Vice President

                                XL RE EUROPE LIMITED

                                By: Stanfield Capital Partners, LLC,
                                as its Collateral Manager

                                By: /s/ Christopher E. Jansen
                                ----------------------------------------------
                                Name: Christopher E. Jansen
                                Title: Managing PartnerExhibit 10.3

                          FIRST SUPPLEMENTAL INDENTURE

THIS FIRST SUPPLEMENTAL INDENTURE (this "Supplemental Indenture") is entered
into as of April 2, 2007, by and between Greatbatch, Inc., a Delaware
corporation (the "Company"), and Manufacturers and Traders Trust Company, a New
York banking corporation, as trustee (the "Trustee").

THE PARTIES TO THIS SUPPLEMENTAL INDENTURE enter into this Supplemental
Indenture on the basis of the following facts, intentions and understandings:

A. The Company and the Trustee are parties to that certain Indenture dated as of
March 28, 2007 (the "Indenture"), pursuant to which the Company issued
$130,000,000 in aggregate principal amount of the Company's 2 1/4% Convertible
Subordinated Debentures Due 2013 (the "Debentures").

B. The Company desires to reopen the Indenture and issue Additional Debentures
in the aggregate principal amount of $67,782,000 (the "Supplemental
Debentures"), in accordance with the provisions of Section 2.01 of the
Indenture, as set forth in this Supplemental Indenture.

C. Section 12.01(h) of the Indenture provides that the parties hereto may
execute and deliver this Supplemental Indenture to supplement the Indenture
without notice to or consent of any Debentureholder.

D. In order to reopen the Indenture in accordance with Section 2.01 thereof, the
Company desires that (1) the Supplemental Debentures and the Initial Debentures
be treated as part of the same issue of debt instruments for purposes of U.S.
federal income tax laws; (2) the Supplemental Debentures have the same CUSIP
number as the Initial Debentures; and (3) the Trustee receive an Officers'
Certificate and an Opinion of Counsel to the effect that the issuance of the
Supplemental Debentures complies with the provisions of the Indenture.

E. The Company desires and has requested the Trustee to join with it in entering
into this Supplemental Indenture for the purpose of amending the Indenture and
to modify and amend the Indenture to the extent and as set forth in this
Supplemental Indenture.

F. The Company and the Trustee are duly authorized pursuant to the terms of the
Indenture (including, without limitation, Section 12.01 thereof) to execute and
deliver this Supplemental Indenture and to modify and amend the Indenture as
provided herein.

G. Certain officers of the Company, acting pursuant to the authorization of the
Board of Directors of the Company, have determined that the amendments to the
Indenture set forth in this Supplemental Indenture are reasonably necessary and
in the best interests of the Company.

NOW, THEREFORE, in consideration of the mutual covenants and agreements set
forth herein, and for other good and valuable consideration, the receipt and
sufficiency of which are hereby acknowledged, the parties hereto agree as
follows:

                                    ARTICLE 1
                             AMENDMENTS TO INDENTURE

Section 1.1 Amendment of Section 1.01 of the Indenture.
            ------------------------------------------

(a) Section 1.01 of the Indenture is hereby amended by inserting the following
definition, which shall be inserted in alphabetical order:

"Supplemental Debentures" means Debentures in an aggregate principal amount of
$67,782,000 issued pursuant to that certain Supplemental Indenture dated as of
April 2, 2007. The Supplemental Debentures are Additional Debentures as defined
in the Indenture.

<PAGE>

                                    ARTICLE 2
                        ISSUANCE OF ADDITIONAL SECURITIES

Section 2.1 Issuance of Additional Debentures.
            ---------------------------------

(a) Pursuant to Section 2.01 of the Indenture, the Trustee shall authenticate
and make available for delivery the Supplemental Debentures for original issue
in the aggregate principal amount of up to $67,782,000 upon receipt of a written
order or orders of the Company signed by two Officers of the Company (a "Company
Order"). The Company Order shall specify the amount of Debentures to be
authenticated, shall provide that all such Debentures will be Restricted
Securities represented by a Global Debenture and the date on which each original
issue of Debentures is to be authenticated. The aggregate principal amount of
Supplemental Debentures outstanding at any time may not exceed $67,782,000. The
Company may, from time to time after the execution of this Supplemental
Indenture, execute and deliver to the Trustee for authentication Additional
Debentures, and the Trustee shall thereupon authenticate and deliver said
Additional Debentures to or upon the written order of the Company, without any
further action by the Company hereunder; provided, however, that the Company may
issue Additional Debentures only if: (1) such Additional Debentures and Initial
Debentures are treated as part of the same issue of debt instruments for
purposes of U.S. federal income tax laws; (2) such Additional Debentures shall
have the same CUSIP number as the Initial Debentures; and (3) the Trustee
receives an Officers' Certificate and an Opinion of Counsel to the effect that
such issuance of Additional Debentures complies with the provisions of the
Indenture, including each provision of this paragraph.

(b) The Supplemental Debentures and the Initial Debentures shall be treated as
part of the same issue of debt instruments for purposes of U.S. federal income
tax laws.

(c) The Supplemental Debentures shall have the same CUSIP number as the Initial
Debentures.

(d) The Trustee shall receive an Officers' Certificate and an Opinion of Counsel
to the effect that the issuance of the Supplemental Debentures complies with the
provisions of the Indenture.

                                    ARTICLE 3
                                  MISCELLANEOUS

Section 3.1 Effect of Supplemental Indenture; Timing of Amendments. This
Supplemental Indenture supplements and amends the Indenture pursuant to Section
12.01 of the Indenture. Upon execution and delivery of this Supplemental
Indenture, the Indenture shall be amended and supplemented in accordance
herewith, the terms and conditions of this Supplemental Indenture shall be part
of the terms and conditions of the Indenture for any and all purposes, and all
the terms and conditions of both shall be read together as though they
constitute one and the same instrument, except that in the case of conflict, the
provisions of this Supplemental Indenture will control; and every
Debentureholder heretofore or hereafter authenticated and delivered shall be
bound thereby.

Section 3.2 Definitions. Capitalized terms used and not otherwise defined in
this Supplemental Indenture shall have the meanings given such terms in the
Indenture.

Section 3.3 Full Force and Effect. Except to the extent expressly modified or
amended by this Supplemental Indenture, which modifications and amendments are
deemed necessary to cure ambiguities and correct or supplement any provisions in
the Indenture which are defective or inconsistent with any other provisions
therein, the Indenture and all of its covenants, agreements and other provisions
remain in full force and effect, and all references to the Indenture in the
Indenture shall be deemed to mean the Indenture as supplemented and amended
pursuant hereto.

Section 3.4 Severability. In case any provision in this Supplemental Indenture
shall be invalid, illegal or unenforceable, the validity, legality and
enforceability of the remaining provisions shall not in any way be affected or
impaired thereby.

Section 3.5 Governing Law. THIS SUPPLEMENTAL INDENTURE SHALL BE GOVERNED BY, AND
CONSTRUED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW YORK (WITHOUT GIVING
EFFECT TO CONFLICTS OF LAWS PRINCIPLES THEREOF).

<PAGE>

Section 3.6 Counterparts. The parties may sign any number of copies of this
Supplemental Indenture. Each signed copy shall be an original, but all of them
together represent the same agreement.

Section 3.7 Effect of Headings. The Article and Section headings herein have
been inserted for convenience of reference only, are not to be considered a part
hereof, and shall in no way modify or restrict any of the terms or provisions
hereof.

                            [Signature Page Follows]

<PAGE>

IN WITNESS WHEREOF, the parties hereto have caused this Supplemental Indenture
to be duly executed as of the date first above written.

GREATBATCH, INC.

By:              /s/ Thomas J. Mazza
                 -------------------------------------------------
Name:            Thomas J. Mazza
Title:           Senior Vice President and Chief Financial Officer

MANUFACTURERS AND TRADERS TRUST COMPANY,
as Trustee

By:              /s/ Aaron G. McManus
                 -------------------------------------------------
Name:            Aaron G. McManus
Title:           Assistant Vice President

                 Signature Page to First Supplemental Indenture

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