Document:

Exhibit

Galena Letterhead 
4640 S.W. Macadam Avenue 
Suite 270 
Portland, Oregon 97239
 __, 2014

[Addressee]
Re:    Advancement and Undertaking 
Dear [Addressee]:
As you know, the Board of Directors of Galena Biopharma, Inc. (the “Company”) has established a Special Committee to conduct an investigation relating to, inter alia,  the Company’s retention of The DreamTeam Group for marketing services and the sale of Company stock by you and certain of its other officers and directors (the “Internal Investigation”).  You are also aware that you, together with other officers and directors of Galena, have been named as defendants in one or more complaints filed in the lawsuits described in the attached Schedule of Claims.  The Company is also responding to one or more subpoena from the Securities and Exchange Commission regarding matters raised by the complaints (the “Civil and Regulatory matters”).
The Company and the Special Committee understand that you have engaged [Name of Addressee's counsel] in connection with these matters in connection with this Internal Investigation, as well as to serve as well as “shadow counsel” in the referenced Civil and Regulatory matters.  It is understood that [Addressee’s] role as “shadow counsel” may change and that he may have to enter an appearance on your behalf as the Civil and Regulatory matters evolve.  You have requested that the Company advance the fees and costs incurred by you in connection with [Addressee’s] representation of you in the Internal Investigation, as well as in the Civil and Regulatory matters (or any other related matters) under Article VII of the Amended and Restated Certificate of Incorporation of the Company (formerly RXI Pharmaceuticals Corporation) (“Article VII”) and Section 145 of the Delaware General Corporation Law (“DGCL”).  You understand that, under Article VII and the DGCL, you are entitled to request indemnification for all and advancement of reasonable expenses in connection with these claims and proceedings and any new, related, or follow-on claims, investigations, or proceedings, subject to the conditions set forth below, and that the Company is permitted to indemnify you or to advance your expenses as provided in Article VII and in Section 145 of the DGCL.

-  .

[Addressee]
 ___, 2014
Page 2

The Special Committee has approved your advancement request on the conditions that: 
(a)The fees and costs shall actually and reasonably be incurred by you in connection with the Internal Investigation and the Civil and Regulatory matters described above.  To the extent the fees and costs are applied to the applicable retention amount or reimbursed under the Company’s director and officer liability insurance policies (the “D&O Policies”), they will be irrevocably presumed to be “reasonable” for this purpose. 
(b)    You agree that, once the standard retention under the applicable D&O policies is reached and satisfied (as agreed by the insurer(s)), you will look in the first instance to the D&O insurers for payment of fees and costs.  You do not waive any right at any point to seek to require advancement and indemnification from the Company, should and to the extent that the D&O Insurers ultimately refuse to pay your fees and costs, and without prejudice to any rights you may have under Article VII, the DGCL, or under the applicable D&O Policies.  You understand that the Company does not waive any right at any point to deny such advancement and indemnification, and without prejudice to any rights it may have under Article VII or the DGCL.
(c)    In any event, you hereby undertake to repay all fees and costs so advanced to the extent that it shall ultimately be determined that you are not entitled to be indemnified by the Company under Article VII or the DGCL.
Nothing in this letter shall constitute a waiver of any of your rights, or the rights of the Company, under the D&O Policies, Article VII, or otherwise.  In addition, nothing in this letter shall constitute a waiver of any of the rights of you or the insurers under the D&O Policies, including, but not limited to any primary or Side A coverage.
This letter, together with Article VII, constitutes the entire understanding and agreement among you and the Company with respect to the subject matter of this letter and supersedes any prior or contemporaneous understandings and agreements regarding the same subject matter.
Please acknowledge your agreement to, and acceptance of, the foregoing arrangements by executing and returning a copy of this letter.
Very truly yours,

[Authorized Officer]
	
		
	AGREED TO AND ACCEPTED:

	 

	   
[Addressee]

	 

cc:EX-4.1 - Twelfth Supplemental Indenture, Dated as of March 10, 2016

 Exhibit 4.1 
  

 
 América Móvil, S.A.B.
de C.V., 
 as Issuer 

to 
 The Bank of New York Mellon,

 as Trustee, Security Registrar, Paying Agent and Transfer Agent 

The Bank of New York Mellon, London Branch, 

as London Paying Agent 

and 
 The Bank of New York Mellon
(Luxembourg) S.A., 
 as Luxembourg Paying Agent and Luxembourg Transfer Agent 

 
  

TWELFTH SUPPLEMENTAL INDENTURE 

Dated as of March 10, 2016 
  

 

€850,000,000 
 1.500% Senior
Notes due 2024 
  
  

 TABLE OF CONTENTS 

 

							
	 	 	 	  	Page	 
		
	ARTICLE ONE DEFINITIONS	  	 	1	  
			
	Section 101.	 	 Provisions of the Base Indenture
	  	 	1	  
	Section 102.	 	 Definitions
	  	 	2	  
		
	ARTICLE TWO GENERAL TERMS AND CONDITIONS OF THE NOTES	  	 	3	  
			
	Section 201.	 	 Designation, Principal Amount and Interest Rate
	  	 	3	  
	Section 202.	 	 Denominations
	  	 	4	  
	Section 203.	 	 Computation of Interest
	  	 	4	  
	Section 204.	 	 Forms Generally
	  	 	4	  
	Section 205.	 	 Form of Trustee’s Certificate of Authentication
	  	 	13	  
	Section 206.	 	 Reserved
	  	 	13	  
	Section 207.	 	 Maintenance of Office or Agency
	  	 	13	  
	Section 208.	 	 Euro MTF Market Listing
	  	 	14	  
		
	ARTICLE THREE MISCELLANEOUS PROVISIONS	  	 	14	  
			
	Section 301.	 	 Consent to Service; Jurisdiction
	  	 	14	  
	Section 302.	 	 Governing Law; Waiver of Jury Trial
	  	 	15	  
	Section 303.	 	 Separability of Invalid Provisions
	  	 	15	  
	Section 304.	 	 Execution in Counterparts
	  	 	15	  
	Section 305.	 	 Certain Matters
	  	 	15	  

 TWELFTH SUPPLEMENTAL INDENTURE, dated as of March 10, 2016 (this “Twelfth
Supplemental Indenture”), among América Móvil, S.A.B. de C.V. (the “Company”), a sociedad anónima bursátil de capital variable organized and existing under the laws of the United Mexican
States (“Mexico”), having its principal office at Lago Zurich 245, Plaza Carso / Edificio Telcel, Colonia Ampliación Granada, 11529, Mexico, D.F., Mexico, The Bank of New York Mellon, a banking corporation duly organized and
existing under the laws of the State of New York authorized to conduct a banking business, as Trustee (the “Trustee”), Security Registrar, Paying Agent and Transfer Agent, The Bank of New York Mellon, London Branch, as London Paying
Agent (the “London Paying Agent”), and The Bank of New York Mellon (Luxembourg) S.A., as Luxembourg Paying Agent (the “Luxembourg Paying Agent”) and Luxembourg Transfer Agent (the “Luxembourg Transfer
Agent”), to the Indenture, dated as of June 28, 2012, between the Company and the Trustee (the “Base Indenture”). The Base Indenture, together with this Twelfth Supplemental Indenture, is herein referred to as the
“Indenture.” 
 W I T N E S S E T H: 

WHEREAS, Section 301 of the Base Indenture provides for the issuance from time to time thereunder, in series, of debt Securities of the
Company, and Section 901 of the Base Indenture provides for the establishment of the form or terms of Securities issued thereunder through one or more supplemental indentures; 

WHEREAS, the Company desires by this Twelfth Supplemental Indenture to create a series of Securities to be issued under the Base Indenture, as
supplemented by this Twelfth Supplemental Indenture, and to be known as the Company’s “1.500% Senior Notes due 2024” (the “Notes”), which are to be initially limited in aggregate principal amount as specified in this
Twelfth Supplemental Indenture and the terms and provisions of which are to be as specified in this Twelfth Supplemental Indenture; 

WHEREAS, the Company has duly authorized the execution and delivery of this Twelfth Supplemental Indenture to establish the Notes as a series
of Securities under the Base Indenture and to provide for, among other things, the issuance and form of the Notes and the terms, provisions and conditions thereof, and additional covenants for purposes of the Notes and the Holders thereof; and 

WHEREAS, all things necessary to make this Twelfth Supplemental Indenture a valid agreement of the Company, in accordance with its terms, have
been done. 
 NOW, THEREFORE, for and in consideration of the premises and the purchase and acceptance of the Notes by the Holders thereof
and for the purpose of setting forth, as provided in the Base Indenture, the form of the Notes and the terms, provisions and conditions thereof, the Company covenants and agrees with the Trustee, the London Paying Agent and the Luxembourg Paying
Agent and Luxembourg Transfer Agent as follows: 
 ARTICLE ONE 

DEFINITIONS 
  

	Section 101.	Provisions of the Base Indenture. 

 Except insofar as herein otherwise expressly
provided, all the definitions, provisions, terms and conditions of the Base Indenture shall remain in full force and effect. The Base Indenture, as supplemented by this Twelfth Supplemental Indenture, is in all respects ratified and confirmed,
and the Base Indenture and this Twelfth Supplemental Indenture shall be read, taken and considered as one and the same instrument for all purposes, and every Holder of Notes authenticated and delivered under this

 
Twelfth Supplemental Indenture shall be bound hereby. Notwithstanding any other provision of this Section 101 or the Base Indenture or this Twelfth Supplemental Indenture to the contrary, to
the extent any provisions of this Twelfth Supplemental Indenture or any Notes issued hereunder shall conflict with any provision of the Base Indenture, the provisions of this Twelfth Supplemental Indenture or such Notes, as applicable, shall govern.

  

	Section 102.	Definitions. 

 For all purposes of this Twelfth Supplemental Indenture and the Notes,
except as otherwise expressly provided or unless the subject matter or context otherwise requires: 
 (a) any reference to an
“Article” or a “Section” refers to an Article or Section, as the case may be, of this Twelfth Supplemental Indenture; 

(b) the words “herein,” “hereof” and “hereunder” and other words of similar import refer to
this Twelfth Supplemental Indenture as a whole and not to any particular Article, Section or other subsection; 
 (c) all terms used in this
Twelfth Supplemental Indenture and not defined herein have the meanings assigned to them in the Base Indenture; 
 (d) the term
“Securities,” as defined in the Base Indenture and as used therein (including in any definition therein), shall be deemed to include or refer to, as applicable, the Notes; 

(e) the term “Additional Amounts,” as defined in the Base Indenture and as used therein (including in any definitions
therein), shall be deemed to refer to Additional Interest, as defined in Section 204(b) herein; 
 (f) the term
“Depositary,” as used in the Indenture, shall be deemed to refer, with respect to the Notes, to Clearstream and Euroclear, until a successor Depositary shall have become Depositary pursuant to the applicable provisions of the Base
Indenture, and thereafter “Depositary” shall mean such successor Depositary; and 
 (g) the following terms have the meanings given
to them in this Section 102(g). 
 “Business Day” means each Target System Day. A “Target System Day” is
any day on which the Trans-European Automated Real Time Gross Settlement Express Transfer (TARGET2) System (or any successor thereto) is open for business and a day on which commercial banks are open for dealings in euro deposits in the London
interbank market. With respect to Notes in certificated form, the reference to “Business Day” will also mean a day on which banking institutions generally are open for business in the location of each office of a Transfer Agent, but only
with respect to a payment or other action to occur at that office. 
 “Common Depositary” means The Bank of New York
Mellon, London Branch, as common depositary for the Depositary. 
 “euro” means the euro or such other lawful currency of
the member states of the European Monetary Union that have adopted or that will adopt the single currency in accordance with the Treaty Establishing the European Community, as amended by the Treaty on European Union, as at the time of payment shall
be legal tender for the payment of public and private debts. 

  
 2 

 “Global Note” means a Note that evidences all or part of the Notes and is
authenticated and delivered to, and registered in the name of, the Common Depositary for such Notes or a nominee thereof. 

“Government Securities” means (i) direct obligations of a member state of the European Monetary Union that has adopted the
single currency in accordance with the Treaty Establishing the European Community, as amended by the Treaty on European Union (a “Member State”), (ii) obligations, the timely payment of the principal of and interest on which is
fully and unconditionally guaranteed by a Member State or the European Central Bank, and (iii) certificates, depositary receipts or other instruments which evidence a direct ownership interest in obligations described in Clause (i) or (ii) above or
in any specific principal or interest payments due in respect thereof. 
 “Interest Payment Date” means each March 10,
commencing on March 10, 2017. 
 “Predecessor Note” means, with respect to any particular Note, every previous Note
evidencing all or a portion of the same debt as that evidenced by such particular Note; and, for the purposes of this definition, any Note authenticated and delivered under Section 305 of the Base Indenture in exchange for or in lieu of a mutilated,
destroyed, lost or stolen Note shall be deemed to evidence the same debt as the mutilated, destroyed, lost or stolen Note. 

“Office of the London Paying Agent” means, initially, the office of the London Paying Agent, located at One Canada Square,
London E14 5AL, United Kingdom. 
 ARTICLE TWO 

GENERAL TERMS AND CONDITIONS OF THE NOTES 
  

	Section 201.	Designation, Principal Amount and Interest Rate. 

 (a) There is hereby authorized and
established a series of Securities designated the “1.500% Senior Notes due 2024,” initially in an aggregate principal amount of €850,000,000 (which amount does not include Notes authenticated and delivered upon registration of
transfer of, in exchange for, or in lieu of, other Securities of such series pursuant to Sections 304, 305, 306, 906 or 1105 of the Base Indenture), which amount shall be specified in the Company Order for the authentication and delivery of Notes
pursuant to Section 303 of the Base Indenture. The principal of the Notes shall be due and payable at their Stated Maturity. 
 (b) The
Company may, from time to time and without the consent of the Holders, issue additional notes on terms and conditions identical to those of the Notes (except for issue date, issue price and the date from which interest shall accrue and, if
applicable, first be paid), which additional notes shall increase the aggregate principal amount of, and shall be consolidated and form a single series with, the Notes. 

(c) The Stated Maturity of the Notes shall be March 10, 2024. The Notes shall bear interest at the rate of 1.500% per annum from
March 10, 2016 or from the most recent Interest Payment Date to which interest has been paid or duly provided for, as the case may be, payable annually in arrears on March 10, commencing on March 10, 2017, until the principal thereof
is paid or made available for payment on or prior to the Stated Maturity of the Notes; provided, however, that any amount of interest on any Note which is overdue shall bear interest (to the extent that payment thereof shall be legally

  
 3 

 
enforceable) at the rate per annum then borne by such Note from the date such amount is due to but not including the day it is paid or made available for payment, and such overdue interest shall
be paid as provided in Section 306 of the Base Indenture. 
  

	Section 202.	Denominations. 

 The Notes shall be issued only in denominations of €100,000 and
integral multiples of €1,000 in excess thereof. 
  

	Section 203.	Computation of Interest. 

 Interest on the Notes shall be computed on the basis of the
actual number of days elapsed in an interest period divided by 365 or, in the case of an Interest Payment Date falling in a leap year, 366. 
  

	Section 204.	Forms Generally. 

 The Notes shall be in substantially the forms set forth in this
Section 204, with such appropriate insertions, omissions, substitutions and other variations as are required or permitted by this Twelfth Supplemental Indenture, and may have such letters, numbers or other marks of identification and such legends or
endorsements placed thereon as may be required to comply with the rules of any securities exchange or as may, consistently herewith, be determined by the officers executing such Notes, as evidenced by their execution thereof; provided that if
any Notes are issued in certificated and not global form, such Notes shall be in substantially the form set forth in this Section 204, but shall not contain the legends relating to Global Notes or the “Schedule of Increases or Decreases in
Global Note.” 
 Upon their original issuance, the Notes shall be issued in the form of one or more Global Notes in definitive, fully
registered form, without coupons, substantially in the form set forth in this Section 204. Such Global Notes shall be registered in the name of the Common Depositary, or its nominee, and deposited with the Common Depositary, duly executed by
the Company and authenticated by the Trustee as hereinafter provided. The aggregate amount of any Global Notes may from time to time be increased or decreased by adjustments made on the records of the Common Depositary. 

(a) Form of Face of Note. 

[INCLUDE IF NOTE IS A GLOBAL NOTE AND THE COMMON DEPOSITARY IS THE BANK OF NEW YORK MELLON, LONDON BRANCH, AS COMMON DEPOSITARY FOR
CLEARSTREAM AND EUROCLEAR—THIS NOTE IS A GLOBAL SECURITY AND IS REGISTERED IN THE NAME OF THE BANK OF NEW YORK DEPOSITORY (NOMINEES) LIMITED, AS NOMINEE OF THE BANK OF NEW YORK MELLON, LONDON BRANCH, AS COMMON DEPOSITARY (THE “COMMON
DEPOSITARY”) FOR CLEARSTREAM BANKING, SOCIÉTÉ ANONYME AND EUROCLEAR BANK S.A./N.V. UNLESS AND UNTIL THIS NOTE IS EXCHANGED IN WHOLE OR IN PART FOR NOTES IN DEFINITIVE FORM, THIS NOTE MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE
COMMON DEPOSITARY OR ANOTHER DEPOSITARY OR BY THE COMMON DEPOSITARY OR A NOMINEE OF THE COMMON DEPOSITARY TO A SUCCESSOR DEPOSITARY OR A NOMINEE OF SUCH SUCCESSOR DEPOSITARY.] 

  
 4 

 AMÉRICA MÓVIL, S.A.B. DE C.V. 

1.500% Senior Notes due 2024 
 ISIN Number:
XS1379122101 / Common Code: 137912210 
  

			
	 No.
	  	€

 América Móvil, S.A.B. de C.V. (the “Company,” which term includes any successor
Person under the Indenture hereinafter referred to), a sociedad anónima bursátil de capital variable organized and existing under the laws of the United Mexican States (“Mexico”), for value received, hereby
promises to pay to The Bank of New York Depository (Nominees) Limited, or registered assigns, as the nominee of The Bank of New York Mellon, London Branch, as common depositary for Clearstream Banking, société anonyme and
Euroclear Bank, S.A./N.V., the principal sum of              euro (or such other lawful currency of the member states of the European Monetary Union that have adopted or that will adopt the
single currency in accordance with the Treaty Establishing the European Community, as amended by the Treaty on European Union, as at the time of payment shall be legal tender for the payment of public and private debts), as revised by the Schedule
of Increases and Decreases in Global Note attached hereto on March 10, 2024 (unless earlier redeemed, in which case, on the applicable Redemption Date) and to pay interest thereon from March 10, 2016 or from the most recent Interest
Payment Date to which interest has been paid or duly provided for, as the case may be, annually in arrears on March 10 of each year, commencing on March 10, 2017, at the rate of 1.500% per annum, until the principal hereof is paid or made
available for payment; provided that any principal of, and any premium and interest on, this Note which is overdue shall bear interest (to the extent that payment thereof shall be legally enforceable) at the rate per annum then borne by this
Note from the date such amount is due, to but not including the day it is paid or made available for payment, and such overdue interest shall be paid as provided in Section 306 of the Base Indenture. 

Interest on the Notes shall be calculated on the basis of a 365-day year or, in the case of an Interest Payment Date falling in a leap year, a
366-day year, and the actual number of days elapsed from and including the last Interest Payment Date (or, with respect to interest payable on the first Interest Payment Date, from the issue date of this Note) to but excluding the Interest Payment
Date on which the interest payment falls due. 
 The interest so payable, and punctually paid or duly provided for, on any Interest Payment
Date shall, as provided in the Indenture, be paid to the Person in whose name this Note (or one or more Predecessor Notes) is registered at the close of business on the Regular Record Date for such interest, which shall be the day on which
Clearstream and Euroclear are open for business next preceding such Interest Payment Date. Any such interest not so punctually paid or duly provided for on any Interest Payment Date shall forthwith cease to be payable to the Holder on such
Regular Record Date and may either be paid to the Person in whose name this Note (or one or more Predecessor Notes) is registered at the close of business on a Special Record Date for the payment of such Defaulted Interest to be fixed by the
Trustee, notice whereof shall be given to Holders of this Note not less than 10 days prior to such Special Record Date, or be paid at any time in any other lawful manner not inconsistent with the requirements of any securities exchange on which this
Note may be listed, and upon such notice as may be required by such exchange, all as more fully provided in the Indenture. 
 Payment of the
principal of, and premium, if any, and interest on, this Note shall be made at the office of the Trustee or agency of the Company in the Borough of Manhattan, The City of New York, New York and at the Office of the London Paying Agent and, if and
for so long as the Notes are admitted to listing on the Official List of the Luxembourg Stock Exchange for trading on the Euro MTF 

  
 5 

 
Market, at the office of the Luxembourg Paying Agent, in each case maintained for such purpose and at any other office or agency maintained by the Company for such purpose, in euro (or such other
lawful currency of the member states of the European Monetary Union that have adopted or that will adopt the single currency in accordance with the Treaty Establishing the European Community, as amended by the Treaty on European Union, as at the
time of payment shall be legal tender for the payment of public and private debts) against surrender of this Note in the case of any payment due at the Maturity of the principal thereof (other than any payment of interest that first becomes payable
on a day other than an Interest Payment Date); provided, however, that at the option of the Company, payment of interest may be made by check mailed to the address of the Person entitled thereto as such address shall appear in the
Security Register. [If the Note is a Global Note, then insert: Notwithstanding the foregoing, payment of any amount payable in respect of a Global Note shall be made in accordance with the Applicable Procedures of the Depositary.] 

Reference is hereby made to the further provisions of this Note set forth on the reverse hereof, which further provisions shall, for all
purposes, have the same effect as if set forth at this place. 
 Unless the certificate of authentication hereon has been executed by the
Trustee referred to on the reverse hereof by manual signature, this Note shall not be entitled to any benefit under the Indenture or be valid or obligatory for any purpose. 

IN WITNESS WHEREOF, the Company has caused this instrument to be duly executed. 

Dated:                 

 

			
	AMÉRICA MÓVIL, S.A.B. DE C.V.
		
	By:	 	  

		 	Name:
		 	Title:
		
	By:	 	  

		 	Name:
		 	Title:

 This is one of the Notes referred to in the within-mentioned Indenture. 

Dated:                 

 

			
	 THE BANK OF NEW YORK MELLON,
 as
Trustee

		
	By:	 	  

		 	Authorized Officer

  
 6 

 (b) Form of Reverse of Note. 

This Note is one of a duly authorized issue of securities of the Company (the “Notes”), issued under the Indenture, dated as
of June 28, 2012 (the “Base Indenture”), between the Company and The Bank of New York Mellon, as Trustee (the “Trustee,” which term includes any successor trustee under the Indenture), Security Registrar,
Paying Agent and Transfer Agent, as supplemented by the Twelfth Supplemental Indenture dated as of March 10, 2016 (the “Twelfth Supplemental Indenture” and, together with the Base Indenture, the “Indenture”)
among the Company, the Trustee, The Bank of New York Mellon, London Branch, as London Paying Agent, and The Bank of New York Mellon (Luxembourg) S.A., as Luxembourg Paying Agent and Luxembourg Transfer Agent, and reference is hereby made to the
Indenture for a statement of the respective rights, limitations of rights, duties and immunities thereunder of the Company, the Trustee and the Holders of the Notes and of the terms upon which the Notes are, and are to be, authenticated and
delivered. The terms, conditions and provisions of this Note are those stated in the Indenture (including those made a part of the Indenture by reference to the Trust Indenture Act) and those set forth in this Note. This Note is one of the series
designated on the face hereof. 
 Additional notes on terms and conditions identical to those of this Note (except for issue date, issue
price and the date from which interest shall accrue and, if applicable, the date on which interest will first be paid) may be issued by the Company without the consent of the Holders of the Notes. The amount evidenced by such additional Notes
shall increase the aggregate principal amount of, and shall be consolidated and form a single series with, the Notes, in which case the Schedule of Increases and Decreases in Global Note attached hereto will be correspondingly adjusted. 

In any case where any Interest Payment Date, Redemption Date or Stated Maturity of any Note shall not be a Business Day, then (notwithstanding
any other provision of the Indenture or of the Notes) payment of principal and premium, if any, or interest need not be made on such date, but may be made on the next succeeding Business Day with the same force and effect as if made on the Interest
Payment Date, Redemption Date or at the Stated Maturity, as the case may be; provided that no interest shall accrue for the period from and after such Interest Payment Date, Redemption Date or Stated Maturity, as the case may be. 

In the event of redemption of this Note in part only, a new Note or Notes of this series and of like tenor for the unredeemed portion hereof
shall be issued in the name of the Holder hereof upon the cancellation hereof. 
 If an Event of Default with respect to the Notes shall
occur and be continuing, the principal of all of the Notes may be declared due and payable in the manner and with the effect provided in the Indenture. 

  
 7 

 All payments of principal, premium, if any, and interest in respect of the Notes shall be made
after withholding or deduction for any present or future taxes, duties, assessments or governmental charges of whatever nature imposed, levied, collected, withheld or assessed by or on behalf of Mexico or any authority therein or thereof having
power to tax (“Mexican Taxes”). In the event of any withholding or deduction for any Mexican Taxes, the Company shall pay such additional interest (“Additional Interest”) as will result in receipt by the Holders of
Notes on the respective due dates of such amounts as would have been received by them had no such withholding or deduction (including for any Mexican Taxes payable in respect of Additional Interest) been required, except that no such Additional
Interest shall be payable with respect to any payment on a Note to the extent: 
 (i) that any such taxes, duties,
assessments or other governmental charges are imposed solely because of (A) a connection between the Holder and Mexico, other than the ownership or holding of such Note and the mere receipt of payments with respect to such Note, or (B) failure by
the Holder or any other Person to comply with any certification, identification or other reporting requirement concerning the nationality, residence, identity or connection with Mexico of the Holder or any beneficial owner of such Note if compliance
is required by law, regulation or by an applicable income tax treaty to which Mexico is a party, as a precondition to exemption from, or reduction in the rate of, the tax, assessment or other governmental charge and the Company has given the Holders
at least 30 days’ notice prior to the first payment date with respect to which such certification, identification or reporting requirement is required to the effect that Holders will be required to provide such information and identification;

 (ii) of any such taxes, duties, assessments or other governmental charges with respect to such Note presented for payment
more than 15 days after the date on which such payment became due and payable or the date on which payment thereof is duly provided for and notice thereof given to Holders, whichever occurs later, except to the extent that the Holder of such Note
would have been entitled to such Additional Interest on presenting such Note for payment on any date during such 15-day period; 

(iii) of estate, inheritance, gift or other similar taxes, assessments or other governmental charges imposed with respect to
such Note; 
 (iv) of any tax, duty, assessment or other governmental charge payable other than by deduction or withholding
from payments on such Note; 
 (v) of any payment on such Note to a Holder who is a fiduciary or partnership or a person
other than the sole beneficial owner of any such payment, to the extent that a beneficiary or settlor with respect to such fiduciary, a member of such a partnership or the beneficial owner of such payment would not have been entitled to the
Additional Interest had such beneficiary, settlor, member or beneficial owner been the Holder of such Note; 
 (vi) of any
tax, duty, assessment or other governmental charge imposed on a payment to an individual and required to be made pursuant to European Council Directive 2003/48/EC on the taxation of savings income (as amended from time to time), or any law or
agreement implementing or complying with, or introduced in order to conform to, such directive; and 
 (vii) any combination
of the items in Clauses (i) through (vi) above. 
 For purposes of the provisions described in Clause (i) above, the term “Holder”
of any Note means the direct nominee of any beneficial owner of such Note, which holds such beneficial owner’s interest in such Note. Notwithstanding the foregoing, the limitations on the Company’s obligation to pay Additional Interest set
forth in Clause (i)(B) above shall not apply (a) if the provision of information, documentation or other evidence described in such Clause (i)(B) would be materially more onerous, in form, in procedure or in the substance of information disclosed,
to a Holder or beneficial owner of a Note (taking into account any relevant differences between U.S. and Mexican law, regulation or administrative practice) than comparable information or other reporting requirements imposed under

  
 8 

 
U.S. tax law (including the United States - Mexico Income Tax Treaty), regulations (including proposed regulations) and administrative practice or (b) unless the provision of the
information, documentation or other evidence described in such Clause (i)(B) is expressly required by the applicable Mexican tax regulations and the Company cannot obtain such information, documentation or other evidence on its own through
reasonable diligence and the Company otherwise would meet the requirements for application of the applicable Mexican tax regulations. In addition, such Clause (i)(B) shall not be construed to require that a non-Mexican pension or retirement fund or
a non-Mexican financial institution or any other Person register with the Ministry of Finance and Public Credit for the purpose of establishing eligibility for an exemption from or reduction of Mexican
withholding tax. 
 The Company shall provide the Trustee with the constancia or other relevant documentation, if any (which may
consist of certified copies of such documentation), satisfactory to the Trustee evidencing the payment of Mexican Taxes in respect of which the Company has paid any Additional Interest. Copies of such documentation shall be made available to
the Holders of the Notes or any Paying Agent, as applicable, upon request therefor. 
 The Company shall pay all stamp, issue, registration,
documentary or other similar duties, if any, which may be imposed by Mexico or any governmental entity or political subdivision therein or thereof, or any taxing authority of or in any of the foregoing, with respect to the Indenture or the issuance
of the Notes. 
 All references herein and in the Indenture to principal, premium, if any, interest or any other amount payable in respect
of any Note shall be deemed to include all Additional Interest, if any, payable in respect of such principal, premium, interest or other amount payable, unless the context otherwise requires, and express mention of the payment of Additional Interest
in any provision hereof shall not be construed as excluding reference to Additional Interest in those provisions hereof where such express mention is not made. 

In the event that Additional Interest actually paid with respect to the Notes pursuant to the preceding paragraphs is based on rates of
deduction or withholding of withholding taxes in excess of the appropriate rate applicable to the Holder of such Notes, and, as a result thereof such Holder is entitled to make claim for a refund or credit of such excess from the authority imposing
such withholding tax, then such Holder shall, by accepting such Notes, be deemed to have assigned and transferred all right, title, and interest to any such claim for a refund or credit of such excess to the Company. However, by making such
assignment, the Holder makes no representation or warranty that the Company will be entitled to receive such claim for a refund or credit and incurs no other obligation with respect thereto. 

All references herein and in the Indenture to principal in respect of any Note shall be deemed to mean and include any Redemption Price
payable in respect of such Note pursuant to any redemption right hereunder (and all such references to the Stated Maturity of the principal in respect of any Note shall be deemed to mean and include the Redemption Date with respect to any such
Redemption Price), and all such references to principal, premium, interest or Additional Interest shall be deemed to mean and include any amount payable in respect hereof pursuant to Section 1009 of the Base Indenture. 

The Company may, at its option, redeem the Notes upon not less than 30 nor more than 60 days’ notice, at any time and, only in the case
of Clause (ii) below, from time to time: 
 (i) in whole but not in part, at a Redemption Price equal to the sum of (A) 100%
of the principal amount of the Notes being redeemed, (B) accrued and unpaid interest thereon to the 

  
 9 

 
Redemption Date and (C) any Additional Interest which would otherwise be payable thereon up to but not including the Redemption Date, solely if, as a result of any amendment to, or change in, the
laws (or any rules or regulations thereunder) of Mexico or any political subdivision or taxing authority thereof or therein affecting taxation or any amendment to or change in an official interpretation or application of such laws, rules or
regulations, which amendment to or change in such laws, rules or regulations becomes effective on or after March 10, 2016, the Company would be obligated, after making reasonable endeavors to avoid such requirement, to pay Additional Interest
in excess of the Additional Interest that the Company would be obligated to pay if payments made on the Notes were subject to withholding or deduction of Mexican Taxes at the rate of 4.9%; provided, however, that (1) no notice of redemption
pursuant to this Clause (i) may be given earlier than 90 days prior to the earliest date on which the Company would be obligated to pay such Additional Interest if a payment on the Notes were then due and (2) at the time such notice of redemption is
given, the Company’s obligation to pay such Additional Interest remains in effect; and 
 (ii) in whole or in part, at a
Redemption Price equal to the greater of (1) 100% of the outstanding principal amount of the Notes being redeemed and (2) the sum of the present values of the remaining scheduled payments of principal and interest thereon (exclusive of interest
accrued to the Redemption Date) discounted to the Redemption Date on an annual basis (calculated using a 365-day year or a 366-day year, as applicable, and the actual number of days elapsed) at the Bund Rate plus 0.250% (25 basis points), plus, in
the case of (1) and (2), accrued and unpaid interest on the principal amount of such Notes to but not including the Redemption Date. 
 For
purposes of Clause (ii) above, the following terms shall have the specified meanings: 
 “Bund Rate” means, as of any
Redemption Date, the rate per annum equal to the yield to maturity as of such Redemption Date of the Comparable German Bund Issue, assuming a price for the Comparable German Bund Issue (expressed as a percentage of its principal amount) equal to the
Comparable German Bund Price for such Redemption Date. 
 “Comparable German Bund Issue” means the German Bundesanleihe
security selected by any Reference German Bund Dealer as having a fixed maturity most nearly equal to the remaining term of the Notes to be redeemed and that would be utilized at the time of selection and in accordance with customary financial
practice, in pricing new issues of euro-denominated corporate debt securities in a principal amount approximately equal to the then outstanding principal amount of the Notes to be redeemed and of a maturity most nearly equal to the remaining term of
the Notes to be redeemed; provided, however, that, if the remaining term of the Notes to be redeemed is not equal to the fixed maturity of the German Bundesanleihe security selected by such Reference German Bund Dealer, the Bund Rate shall be
determined by linear interpolation (calculated to the nearest one-twelfth of a year) from the yields of German Bundesanleihe securities for which such yields are given, except that if the remaining term of the Notes to be redeemed is less than one
year, a fixed maturity of one year shall be used. 
 “Comparable German Bund Price” means, with respect to any Redemption
Date, the average of all Reference German Bund Dealer Quotations for such date (which, in any event, must include at least two such quotations), after excluding the highest and lowest such Reference German Bund Dealer Quotations, or if the Trustee
obtains fewer than four such Reference German Bund Dealer Quotations, the average of all such quotations. 

  
 10 

 “Reference German Bund Dealer” means each of Citigroup Global Markets Limited,
HSBC Bank plc and Société Générale, or their affiliates, which are dealers of German Bundesanleihe securities and one other leading dealer of German Bundesanleihe securities reasonably designated by the Company;
provided, however, that if any of the foregoing shall cease to be a dealer of German Bundesanleihe securities, the Company will substitute therefor another dealer of German Bundesanleihe securities. 

“Reference German Bund Dealer Quotation” means, with respect to each Reference German Bund Dealer and any Redemption Date, the
average, as determined by the Trustee, of the bid and asked prices for the Comparable German Bund Issue (expressed in each case as a percentage of its principal amount) quoted in writing to the Trustee by such Reference German Bund Dealer at 3:30
p.m. (Frankfurt, Germany time) on the third business day preceding such Redemption Date. 
 The Indenture permits, with certain exceptions
as therein provided, the amendment thereof and the modification of the rights and obligations of the Company, on the one hand, and the rights of the Holders of the Notes, on the other hand, at any time by the Company and the Trustee with the consent
of the Holders of a majority in principal amount of the Notes at the time Outstanding. The Indenture also contains provisions (1) permitting the Holders of a majority in principal amount of the Notes at the time Outstanding, on behalf of the
Holders of all Notes, to waive compliance by the Company with certain provisions of the Indenture and (2) permitting the Holders of a majority in principal amount of the Notes at the time Outstanding, on behalf of the Holders of all Notes, to waive
certain past defaults under the Indenture and their consequences. Any such consent or waiver by the Holder of this Note shall be conclusive and binding upon such Holder and upon all future Holders of this Note and of any Note issued upon the
registration of transfer hereof or in exchange herefor or in lieu hereof, whether or not notation of such consent or waiver is made upon this Note. 

As provided in and subject to the provisions of the Indenture, the Holder of this Note shall not have the right to institute any proceeding
with respect to the Indenture or for the appointment of a receiver or trustee, or for any other remedy thereunder, unless such Holder shall have previously given the Trustee written notice of a continuing Event of Default with respect to the Notes,
the Holders of not less than 25% in principal amount of the Notes at the time Outstanding shall have made written request to the Trustee to institute proceedings in respect of such Event of Default as Trustee and offered the Trustee indemnity
reasonably satisfactory to it, and the Trustee shall not have received from the Holders of a majority in principal amount of Notes at the time Outstanding a direction inconsistent with such request, and shall have failed to institute any such
proceeding, for 60 days after receipt of such notice, request and offer of indemnity. The foregoing shall not apply to any suit instituted by the Holder of this Note for the enforcement of any payment of principal hereof or premium, if any,
and/or interest hereon on or after the respective due dates expressed herein. 
 No reference herein to the Indenture and no provision of
this Note or of the Indenture shall alter or impair the obligation of the Company, which is absolute and unconditional, to pay the principal of and premium, if any, and interest on this Note at the times, place and rate, and in the coin or currency,
herein prescribed. 
 As provided in the Indenture, and subject to certain limitations therein set forth (including, without limitation, the
restrictions on transfer under Section 304 of the Base Indenture), the transfer of this Note is registrable in the Security Register, upon surrender of this Note for registration of transfer at the office of the Trustee or agency of the Company in
any place where the principal of and any 

  
 11 

 
premium and interest on this Note are payable, duly endorsed by, or accompanied by a written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed
by, the Holder hereof or his attorney duly authorized in writing, and thereupon one or more new Notes of this series and of like tenor, of authorized denominations and for the same aggregate principal amount, shall be issued to the designated
transferee or transferees. 
 The Notes are issuable only in registered form without coupons in denominations of €100,000 and integral
multiples of €1,000 in excess thereof. As provided in the Indenture, and subject to certain limitations therein set forth, Notes are exchangeable for a like aggregate principal amount of Notes of like tenor of a different authorized
denomination, as requested by the Holder surrendering the same. 
 No service charge shall be made for any such registration of transfer or
exchange, but the Company or the Trustee may require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 

Prior to due presentment of this Note for registration of transfer, the Company, the Trustee and any agent of the Company or of the Trustee
may treat the Person in whose name this Note is registered as the owner hereof for all purposes, whether or not this Note is overdue, and neither the Company, the Trustee nor any such agent shall be affected by notice to the contrary. 

[If the Note is a Global Note, then insert: This Note is a Global Note and is subject to the provisions of the Indenture relating to
Global Notes, including the limitations in Section 304 of the Base Indenture on transfers and exchanges of Global Notes.] 
 This Note and
the Indenture shall be governed by, and construed in accordance with, the law of the State of New York. 
 All terms used in this Note which
are defined in the Indenture and not otherwise defined herein shall have the meanings assigned to them in the Indenture. 
  

 
 ABBREVIATIONS

 The following abbreviations, when used in the inscription of the face of this Note, shall be construed as though they were written out in
full according to applicable laws or regulations: 
  

			
	TEN COM -    as tenants in common	  	UNIF GIFT MIN ACT—                    
		  	(Cust)
	TEN ENT -   as tenants by the entireties	  	Custodian                      under Uniform
		  	 (Minor)

	JT TEN - as joint tenants with right of survivorship and not as tenants in common	  	Gifts to Minors Act                     
	  	 (State)

 Additional abbreviations may also be used 

though not in the above list. 
  

 
  

  
 12 

 SCHEDULE OF INCREASES OR DECREASES IN GLOBAL NOTE 

The following increases or decreases in this Global Note have been made: 

 

									
	 Date of transfer or exchange
	  	Amount of decrease
in principal amount
of this Global Note	  	Amount of increase
in principal amount
of this Global Note	  	Principal amount of
this Global Note
following such
decrease or increase	  	Signature of
authorized signatory
of Trustee or
Security Registrar
		  		  		  		  	
		  		  		  		  	
		  		  		  		  	

  

	Section 205.	Form of Trustee’s Certificate of Authentication 

 The Trustee’s
certificate of authentication shall be in substantially the following form: 
 This is one of the Notes referred to in the within-mentioned
Indenture. 
 Dated: 
  

			
	THE BANK OF NEW YORK MELLON,
	as Trustee
		
	By:	 	  

		 	Authorized Officer

  

	Section 206.	Reserved. 

 Section 207. Maintenance of Office or Agency. 

(a) With respect to any Notes that are not in the form of a Global Note, the Company shall maintain in the Borough of Manhattan, The City of
New York, New York and in London, United Kingdom an office or agency, in each case, in accordance with Section 1002 of the Base Indenture. 

(b) If and for so long as the Notes are admitted to listing on the Official List of the Luxembourg Stock Exchange for trading on the Euro MTF
Market, the Company shall maintain, pursuant to Section 1002 of the Base Indenture, an office or agency in Luxembourg where the Notes may be presented or surrendered for payment, surrendered for registration of transfer or exchange and where notices
and demands to or upon the Company in respect of the Notes and the Indenture may be served. The Company has initially appointed The Bank of New York Mellon (Luxembourg) S.A. as the Luxembourg Paying Agent and the Luxembourg Transfer Agent for such
transfers and exchanges and for such notices and demands in Luxembourg with respect to the Notes. The Bank of New York Mellon (Luxembourg) S.A. has its main offices at 2-4 rue Eugène Rupert, Vertigo Building-Polaris, L-2453 Luxembourg. 

(c) If for any reason The Bank of New York Mellon (Luxembourg) S.A. shall not continue as the Luxembourg Paying Agent or Luxembourg Transfer
Agent for such transfers and exchanges and for such notices and demands in Luxembourg with respect to the Notes, and the Notes are admitted to 

  
 13 

 
listing on the Official List of the Luxembourg Stock Exchange for trading on the Euro MTF Market, the Company shall appoint a substitute Paying Agent and/or Transfer Agent, as applicable, in
Luxembourg, in accordance with the rules then in effect of the Luxembourg Stock Exchange and the provisions of the Indenture and the Notes. Following the appointment of a substitute Paying Agent or Transfer Agent in Luxembourg, the Company
shall give the Holders of the Notes notice of such appointment pursuant to Section 106 of the Base Indenture. 
  

	Section 208.	Euro MTF Market Listing. 

 The Company shall use its reasonable best efforts to have the
Notes admitted to listing on the Official List of the Luxembourg Stock Exchange for trading on the Euro MTF Market; provided, however, that the Company will not be required to maintain such admission to listing and trading. 

ARTICLE THREE 

MISCELLANEOUS PROVISIONS 
  

	Section 301.	Consent to Service; Jurisdiction. 

 Each party hereto agrees that any legal suit, action
or proceeding arising out of or relating to this Twelfth Supplemental Indenture, the Base Indenture or the Notes may be instituted in any federal or state court in the Borough of Manhattan, The City of New York, New York and in the courts of its own
corporate domicile, in respect of actions brought against each such party as a defendant, and each waives any objection which it may now or hereafter have to the laying of the venue of any such legal suit, action or proceeding, waives any immunity
from jurisdiction or to service of process in respect of any such suit, action or proceeding, waives any right to which it may be entitled on account of place of residence or domicile, and irrevocably submits to the jurisdiction of any such court in
any such suit, action or proceeding. The Company hereby designates and appoints CT Corporation System, 111 Eighth Avenue, 13th Floor, New York, New York 10011, as its authorized agent upon which process may be served in any legal suit, action
or proceeding arising out of or relating to this Twelfth Supplemental Indenture or the Notes which may be instituted in any federal or state court in the Borough of Manhattan, The City of New York, New York, and agrees that service of process upon
such agent shall be deemed in every respect effective service of process upon the Company in any such suit, action or proceeding and further designates its domicile, the domicile of CT Corporation System specified above and any domicile CT
Corporation System may have in the future as its domicile to receive any notice hereunder (including service of process). If for any reason CT Corporation System (or any successor agent for this purpose) shall cease to act as agent for service
of process as provided above, the Company will promptly appoint a successor agent for this purpose reasonably acceptable to the Trustee. The Company agrees to take any and all actions as may be necessary to maintain such designation and
appointment of such agent in full force and effect. 
  

	Section 302.	Governing Law; Waiver of Jury Trial. 

 (a) THIS TWELFTH SUPPLEMENTAL INDENTURE AND THE
NOTES SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE LAW OF THE STATE OF NEW YORK. 
 (b) EACH OF THE PARTIES HERETO
(EXCEPT, FOR THE AVOIDANCE OF DOUBT, THE HOLDERS OF THE NOTES) HEREBY WAIVES, TO THE FULLEST EXTENT PERMITTED BY APPLICABLE LAW, ALL RIGHTS TO TRIAL BY JURY IN ANY ACTION, PROCEEDING OR COUNTERCLAIM (WHETHER BASED ON CONTRACT, TORT OR OTHERWISE)
ARISING OUT OF OR RELATING TO THE BASE INDENTURE, THIS TWELFTH SUPPLEMENTAL INDENTURE, THE NOTES OR THE TRANSACTIONS CONTEMPLATED HEREBY OR THEREBY. 

  
 14 

	Section 303.	Separability of Invalid Provisions. 

 In case any one or more of the provisions contained
in this Twelfth Supplemental Indenture should be invalid, illegal or unenforceable in any respect, such invalidity, illegality or unenforceability shall not affect any other provisions contained in this Twelfth Supplemental Indenture, and to the
extent and only to the extent that any such provision is invalid, illegal or unenforceable, this Twelfth Supplemental Indenture shall be construed as if such provision had never been contained herein. 

 

	Section 304.	Execution in Counterparts. 

 This Twelfth Supplemental Indenture may be simultaneously
executed and delivered in any number of counterparts, each of which when so executed and delivered shall be deemed to be an original, and such counterparts shall together constitute but one and the same instrument. 

 

	Section 305.	Certain Matters. 

 (a) The Trustee, the London Paying Agent and the Luxembourg Paying
Agent shall not be responsible in any manner whatsoever for or in respect of the validity or sufficiency of this Twelfth Supplemental Indenture or for or in respect of the recitals contained herein, all of which are made solely by the Company. 

(b) In the performance of its obligations hereunder, the Trustee shall be provided with any rights, benefits, protections, indemnities and
immunities afforded to it pursuant to the Base Indenture. The rights, privileges, protections, immunities and benefits given to the Trustee hereunder and under the Base Indenture are extended to, and shall be enforceable by, the London Paying Agent
and the Luxembourg Paying Agent 
 [Signature page follows] 

  
 15 

 IN WITNESS WHEREOF, the parties hereto have caused this Twelfth Supplemental Indenture to be duly
executed on their respective behalves, all as of the day and year first written above. 
  

					
	AMÉRICA MÓVIL, S.A.B. DE C.V.,
	as Issuer
		
	By:	 	 /s/ Carlos José García Moreno Elizondo

		 	Name:	 	Carlos José García Moreno Elizondo
		 	Title:	 	Chief Financial Officer
		
	By:	 	 /s/ Alejandro Cantú Jiménez

		 	Name:	 	Alejandro Cantú Jiménez
		 	Title:	 	General Counsel

 [Signature page to Twelfth Supplemental Indenture – March 2016 EUR Takedown] 

 
					
	THE BANK OF NEW YORK MELLON,
	as Trustee, Security Registrar, Paying Agent and Transfer Agent
		
	By:	 	 /s/ James Briggs

		 	Name:	 	James Briggs
		 	Title:	 	Vice President
	
	 THE BANK OF NEW YORK MELLON,
 LONDON
BRANCH, as London Paying Agent

		
	By:	 	 /s/ James Briggs

		 	Name:	 	James Briggs
		 	Title:	 	Vice President
	
	THE BANK OF NEW YORK MELLON (LUXEMBOURG) S.A., as Luxembourg Paying Agent and Luxembourg Transfer Agent
		
	By:	 	 /s/ James Briggs

		 	Name:	 	James Briggs
		 	Title:	 	Authorized Signatory

 [Signature page to Twelfth Supplemental Indenture – March 2016 EUR Takedown]

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