Document:

EX-10.38

 Exhibit 10.38 

L E A S E 
 THIS LEASE is
made and entered into this      day of March 2015, by and between JTC, a California general partnership, located at
                     (hereinafter called “Lessor”), and Eiger BioPharmaceuticals, Inc., located at PO Box 430, San Carlos, CA 94070
(hereinafter called “Lessee”), for the promises and on the terms and conditions described herein. 

1.      SCHEDULE: 

A.      PREMISES: Lessor hereby leases to Lessee and Lessee hereby leases from Lessor, that certain office
space (herein called “Premises”) outlined on Exhibit “A” which is incorporated herein by this reference, known as Suite number 350, situated on the 3rd floor of that certain office building commonly known as 350
Cambridge Ave (herein called “Complex”). Rentable Square Feet (“RSF”) of the Premises is estimated and agreed to be 1,570 RSF. RSF of the Premises is not to increase regardless of re-measurement and thus base rent and OPEX shall
not be modified as a result of a change in the RSF unless RSF decreases. 
 The parties hereto agree that said letting and hiring is upon
and subject to the terms, covenants and conditions herein set forth and Lessee covenants as a material part of the consideration for this Lease to keep and perform each and all of said terms, covenants and conditions by it to be kept and performed
and that this Lease is made upon the condition of such performance. 
 B.      TERM: Commencing on
April 1, 2015 or upon completion of leasehold improvements, and ending at 5:00 P.M. thirty-six (36) months later on March 31, 2018 and subject to the provisions herein 

C.      BASE RENT: $9,027.50 per month, payable in equal installments in said amount in advance on the
first day of each month, commencing April 1, 2015, and continuing on the same day of each month for the balance of the term subject to rental increase as provided in Paragraph 1(D). Rent shall be payable to the Lessor at Palo
Alto, California or at such other place as Lessor may designate in writing. The first month’s rent and operating expenses shall be paid in full and the second month’s rent and operating expenses shall be pro-rata based on the occupancy
date. Lessor acknowledges receipt of the following rent upon execution of this lease: $9,027.50 as Rent and $1,334.50 as Direct Expense for April 1, 2015 – April 30, 2015. 

D.      RENTAL INCREASE: Shall be on each anniversary date of this lease as provided in paragraph 30
hereof. 
 E.      PAYMENTS FOR DIRECT EXPENSES. As additional rent Lessee shall pay to Lessor a
proportionate share (as defined below) of direct expenses incurred by Lessor in the operation and maintenance of the Complex (herein “Direct Expenses”). Lessee’s proportionate share shall be the same percentage of Direct Expenses as
the total number of leasable square feet in the Premises bears to the number of leasable square feet in the Complex. 
 Lessor estimates
that Direct Expenses during the balance of the first Calendar year of the Lease term hereunder will be equivalent to $0.85 per month per square foot of leasable square feet in the building. Accordingly, during the balance of the present Calendar
year of the lease term, Lessee shall pay to Lessor $1,334.50 per month on account of Lessee’s additional rent attributable to Direct Expenses. 

The amount to be paid monthly, on account, by Lessee as additional rent for Direct Expenses shall be adjusted annually on January 1st
based upon Lessor’s best estimate of the amount of such direct costs projected for the next twelve (12) month period. For this purpose, Lessor’s statement of estimated Direct Expenses shall specify the monthly amount to be paid on
account by Lessee during the next ensuing twelve (12) month period (which shall be equivalent to one-twelve (1/12) of Lessee’s proportionate share of the estimated Direct Expenses sets forth in such statement) until the next ensuing
annual determination of estimated Direct Expenses. 
 Annually, on the first day of March of each calendar year (or as soon thereafter as
Lessor can reasonably make the determination), Lessor shall determine and provide Lessee with a statement of the actual amount of Direct Expenses incurred by Lessor during the twelve (12) month period ending on December 31st of each year.
If Lessee’s cumulative total of monthly payments on account of Direct Expenses is less than Lessee’s proportionate share of the Actual Direct Expenses during the particular twelve (12) month period, Lessee shall pay the difference to
Lessor within thirty (30) days after the date of Lessor’s statement. If Lessee’s proportionate share of actual Direct Expenses is less than the cumulative total of Lessee’s monthly payments on account of Direct Expenses during
any such twelve (12) month period, the difference shall be credited against amounts thereafter becoming due from Lessee for subsequent payments on account of Direct Expenses or will be paid within thirty (30) days after the date of
Lessor’s statement, at the option of Lessor. 
 “Direct Expenses”, as used in this paragraph, shall include all direct costs
of management, operation and maintenance as determined by standard accounting practices and shall include the following by way of illustration, but not limitation: Real property taxes and assessments upon the buildings and the land upon which they
are located; personal property taxes related to the Complex, taxes of every kind and nature whatsoever levied and assessed in lieu of, in substitution for, or in addition to, existing or 

  
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additional real property taxes on the buildings and the land upon which they are located; taxes based upon, measured by, or otherwise calculated with respect to the gross or net payable under
this Lease, including, without limitation, any gross receipts tax levied by any taxing authority, or any other gross income tax or excise tax levied by any taxing authority with respect to the receipt of the rental hereunder; parking taxes; water
and sewer charges; waste disposal; insurance premiums, license, permit and inspection fees; charges for heat, light, gas electric, power, steam and other utilities (including, without limitation, any temporary or permanent utility surcharge or other
exaction, whether or not hereinafter imposed). and air conditioning; security; janitorial services and maintenance contracts; painting and repairing, interior and exterior; maintenance and replacement of floor and window coverings; repair of roof,
exterior walls, foundations; repair and maintenance of downspouts, air conditioning, mechanical and electrical systems; plumbing sand sewage systems; landscaping and gardening of outside areas; glazing; repair and maintenance of parking lots;
salaries and employee benefits of personnel engaged in the operation and maintenance of the Complex and payroll taxes applicable thereto; materials equipment and tools, the cost of capital expenditures which have the effect of reducing the operating
expenses, provided, however, that in the event Lessor makes such capital improvements, Lessor may amortize its investment in said improvements (together with interest at the rate of twelve per cent (12%) per annum on the unamortized balance) as
an operating expense in accordance with standard accounting practices, provided that such amortization is not at a rate greater than the anticipated savings in the operating expenses. “Direct Expenses”, as used herein, shall not include
Lessor’s debt repayment; interest on charges; expenses directly or indirectly incurred by Lessor solely for the benefit of any other Lessee; cost for the installation of partitioning or any other Lessee improvements; cost of attracting tenants,
depreciation, interest, or executive salaries. Each statement of actual adjustment shall be based upon a determination and statement of Direct Expenses prepared by an auditing or accounting officer of, or designated by, Lessor, and a copy of such
statement of Direct Expenses shall be made available to Lessee upon Lessee’s request thereof. 
 The respective obligations of Lessor
and Lessee under this paragraph shall survive the expiration or other termination of the term of this Lease, and if the term hereof shall expire or shall otherwise terminate on a day other than the last day of a Calendar year, the adjustment in
Direct Expenses for the calendar year in which the term thereof expires or otherwise terminates shall be determined and settled on the basis of the statement of actual adjustment for such calendar year and shall be prorated in that proportion which
the number of days in such Calendar year preceding such expiration or termination bears to three hundred sixty-five (365). 

F.      SECURITY DEPOSIT: $20,724 in cash, receipt of which is hereby acknowledged. This sum represents
the equivalent of the last two (2) months base rent plus NNN charges. 
 G.      USE OF PREMISES:
General business purposes 
 H.      REPRESENTATIONS RE CONDITION OF PREMISES: Lessee improvements
to be constructed as provided in Exhibit “A” hereof. 
 I.      SERVICES TO BE PROVIDED BY
LESSOR: Five-day-a-week janitor, common area heating, ventilating and water shall be provided by Lessor. Electricity, heat and air-conditioning to the Premises shall be separately metered and paid by Lessee. 

J.      LEASEHOLD IMPROVEMENTS TO BE PROVIDED BY LESSOR: Building Standard” improvements as
specified on Exhibit “A” hereof. 
 K.      REMOVAL OF PROPERTY: At any time Lessee may, and
prior to the end of the lease term Lessee shall, remove from the Premises furniture, equipment, and other personal property installed by Lessee or at Lessee’s expense. Lessee shall not remove any fixtures or leasehold improvements without
Lessor’s prior written consent, except fixtures installed by Lessee which can be removed without damage to the premises. Lessee shall repair any damage to the Premises caused by removal of any property, and shall restore the Premises to its
condition at the commencement of the term, less reasonable wear and tear. All of such removal and restoration shall be accomplished at Lessee’s expense prior to the end of the lease term. 

L.      LESSEE’S INSURANCE: Bodily Injury and Property Damage Liability insurance of not less than
One Million Dollars ($1,000,000) combined each occurrence and as further specified in paragraph 11 hereof. 

M.      TAXES: Percent of Building occupied by Lessee - 6.18% 

N.      BROKERS: 
  

			
	Jones Lang LaSalle	  	Cornish & Carey Commercial
	Scott W Miller	  	dba Newmark Cornish & Carey
	Chris Crow	  	Wayne Kumagai
		  	John McKenna

  
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 2.      TERM AND RENT: The term of this lease and the rent
which Lessee agrees to pay to Lessor are specified in the Schedule. Lessee agrees to pay the rent to Lessor in lawful money of the United States of America, without deduction or offset. Rent for partial months shall be prorated. 

Lessee additionally agrees to pay to Lessor, concurrent with the Base Rent unless otherwise provided herein, all other sums of money that may
become due and payable hereunder, which sums shall be deemed additional rental. 
 3.      DEPOSIT:
Upon the execution of this lease, Lessee will pay to lessor as a security deposit the sum specified as “Deposit” in the Schedule. If Lessee shall pay all rent and observe and perform all of the terms, covenants, and conditions of this
lease during the term and all extensions and renewals thereof, Lessor will repay the deposit to Lessee, without interest, within five (5) business days after Lessee vacates the Premises. If Lessee defaults in the payment of rent or other sums
due hereunder, damages the Premises, fails to leave the Premises clean upon termination of the tenancy, or defaults in any of the other terms, covenants or conditions of this lease, Lessor may use or apply so much of the security deposit as is
reasonably necessary to remedy such default. Lessee agrees to restore the security deposit to the full original amount immediately upon receipt of demand from Lessor therefor. 

4.      POSSESSION: If Lessor is unable to deliver possession of the Premises to Lessee at the
commencement of the term for any reason whatsoever, the lease shall not be void or voidable for a period of forty-five (45) days thereafter, nor shall Lessor be liable to Lessee for any loss or damage resulting therefrom, but the rent shall
abate until Lessor delivers possession of the Premises to Lessee. If Lessor is unable to deliver possession of the Premises within forty-five (45) days after the commencement date, this lease may be terminated by either Lessor or Lessee by a
written notice to the other at any time thereafter prior to the date possession is delivered to Lessee. 

5.      USE: The Premises shall be used for the purpose specified in the Schedule Paragraph 1G, and for
no other purpose without the prior written consent of Lessor. 
 Lessee shall not do or permit anything to be done in or about the Premises
nor bring or keep anything therein which will in any way increase the existing rate of or affect any fire or other insurance upon the Building or any of its contents, cause cancellation of any insurance policy covering said Building or any part
thereof or any of its contents. Lessee shall not do or permit anything to be done in or about the Premises which will in an way obstruct or interfere with the rights of other tenants or occupants of the Building or injure or annoy them or use or
allow the Premises to be used for any improper, immoral, unlawful or objectionable purpose, nor shall Lessee cause, maintain or permit any nuisance in, on or about the Premises. Tenants shall not commit or suffer to be committed any waste in or upon
the Premises. 
 6.      ABANDONMENT: Lessee will not vacate, abandon, or surrender the Premises during
the term, and if Lessee does, or is dispossessed by process of law, or otherwise, any personal property belonging to Lessee left on the Premises shall be deemed to be abandoned at the option of Lessor. 

7.      CONDITION OF PREMISES: Lessee’s taking possession of the Premises and occupying the same for
thirty (30) days without giving written notice to Lessor within said period of any defect in the Premises shall be conclusive evidence as against Lessee that the Premises were in good order and satisfactory condition when Lessee took
possession. No promise to alter, remodel, or improve the Premises or the Building and no representation respecting the condition of the Premises or the Building have been made by Lessor to Lessee, unless the same is set forth in the Schedule. Lessee
waives all right to make repairs at the expense of Lessor, or to deduct the cost thereof from the rent, and Lessee waives all rights under Sections 1941 and 1942 of the Civil Code of the State of California. At the termination of this lease by lapse
of time or otherwise, Lessee shall surrender the Premises in as clean and good a condition as when Lessee took possession, ordinary wear or loss by fire or other natural force excepted, failing which Lessor may restore the Premises to such condition
and Lessee shall pay the cost thereof to Lessor upon demand. 
 8.      ALTERATIONS AND REPAIRS: Lessee
shall not make or permit to be made any alterations, additions, improvements, or changes in the Premises without the prior written consent of Lessor, which consent Lessor shall not unreasonably withhold, provided that Lessor may make such consent
subject to reasonable conditions. Subject to the services to be rendered by Lessor as set forth in the Schedule, Lessee shall, at Lessee’s own expense, keep the Premises in good order, condition, and repair during the term, including the
replacement of all broken glass with glass of the same size and quality under the supervision and with the approval of Lessor. If Lessee does not make repairs promptly and adequately, Lessor may, but need not, make repairs and Lessee shall pay
promptly the reasonable cost thereof. At any time or times, Lessor, either voluntarily or pursuant to governmental requirements, may, at Lessor’s own expense, make repairs, alterations, or improvements in or to the Building or any part thereof,
including the Premises, and, during such operations Lessor may close entrances, doors, corridors, elevators, or other facilities, all without any liability to Lessee by reason of interference, inconvenience, or annoyance; provided that Lessee shall
have access to the Premises sufficient for conduct of Lessee’s business. Lessor shall not be liable to Lessee for any expense, injury, loss, or damage resulting from work done in or upon, or the use of, any adjacent or nearby building, land,
street, or alley, provided that Lessor makes a reasonable effort to minimize the disruption to Lessee’s business. In the event 

  
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Lessee requests that repairs, alterations, decorating, or other work in the Premises be made during periods other than ordinary business hours, Lessee shall pay Lessor for overtime and other
additional expenses incurred because of such request. 
 9.      LIENS: Lessee agrees to keep the
Premises and the property on which the Premises are located free from any liens arising out of any work performed, materials furnished, or obligations incurred by Lessee. 

10.      INDEMNIFICATION: Lessee waives all claims against Lessor for damages to property, or to goods,
wares and merchandise stored in, upon, or about the Premises, and for injuries to persons in, upon or about the Premises from any cause arising at any time, except as may be caused by the act, omission, or negligence of Lessor, and Lessee agrees to
indemnify and hold Lessor exempt and harmless for and on account of any damage or injury to any person or property arising from the use of the Premises by Lessee or from the failure of Lessee to keep the Premises in good condition as herein
provided. Lessor shall not be liable to Lessee for any damage because of any act or negligence of any covenant or other occupant of the same Building, or by any owner or occupant of adjourning or contiguous property, nor for overflow, breakage,
or leakage of water, steam, gas, or electricity from pipes, wires, or otherwise. Lessee will pay for all damage to the Building and to the tenants and occupants thereof caused by the misuse or neglect of the Premises by Lessee or its invitees. 

Lessee’s obligations to indemnify and defend shall include, without limitation, the obligation to pay Lessor’s reasonable attorney
fees and other costs incurred after Lessor’s first notice of each such claim. 

11.      LESSEE’S INSURANCE OBLIGATION: Lessee further covenants and agrees that from and after
substantial completion of the premises Lessee will carry and maintain, at its sole cost and expense, the following types of insurance, in the amounts specified and in the form hereinafter provided for: 

A.      PUBLIC LIABILITY AND PROPERTY DAMAGE. Bodily injury and property damage liability insurance with
coverage limits of not less than One Million Dollars ($1,000,000) combined each occurrence and in the aggregate insuring against any and all liability of the insured with respect to said premises or arising out of the maintenance, use or occupancy
thereof. All such bodily injury liability insurance and property damage liability insurance shall specifically insure the performance by Lessee of the indemnity agreement as to liability for injury or death of persons and damage to property in this
Article 11 contained. 
 B.      PLATE GLASS: Insurance covering all plate glass on the premises.
Lessee shall have the option to either insure the risk or to self-insure. 
 C.      EQUIPMENT:
Machinery insurance on all air conditioning equipment and systems exclusively serving the premises. If said equipment and the damage that it may cause are not covered by Lessee All Risk insurance, then the insurance specified in this
subparagraph C. shall be in an amount not less than One Hundred Thousand Dollars ($100,000). If Lessee requires boilers or other pressure vessels to serve the premises, they should also be insured in the amount required by this subparagraph. 

D.      LESSEE IMPROVEMENTS: Insurance covering Lessee’s fixtures, merchandise, and personal
property from time to time in, on or upon the premises, in an amount not less than ninety (90%) percent of their full replacement cost from time to time after the Effective Date providing protection against any peril included within the
classification “All Risk,” together with insurance against sprinkler damage. Any policy proceeds shall be used for the repair or replacement of the property damaged or destroyed unless this Lease shall cease and terminate under the
provisions of Article 15. 
 E.      POLICY FORM. 

E.1.      All policies of insurance provided for herein shall be issued by insurance companies with
general policyholder’s rating of not less than A and a financial rating of not less than Class X as rating in the most current available “Best’s” Insurance Reports, qualified to do business in the State where the Premises are
situated. All such policies shall be issued in the names of Lessor and Lessee, and if requested by Lessor, Lessor’s first mortgagee or beneficiary, which policies shall be for the mutual and joint benefit and protection of Lessor, Lessee and
Lessor’s first mortgagee or beneficiary. Executed copies of such policies of insurance or certificates thereof shall be delivered to Lessor within (10) ten days after substantial completion of the premises, and thereafter executed copies
of renewal policies or certificates thereof shall be delivered to Lessor within thirty (30) days prior to the expiration of the term of each such policy. All public liability damage and property damage policies shall contain a provision that
Lessor, although named as an insured, shall nevertheless be entitled to recover under said policies for any loss occasioned to it, its servants, agents and employees by reason of the negligence of Lessee. As often as any such policy shall expire or
terminate, renewal or additional policies shall be procured and maintained by Lessee in like manner and to like extent. Lessee shall provide Lessor any written notice given to Lessee from company within thirty (30) days except ten
(10) days notice due to non-payment cancellation. All public liability, property damage and other casualty policies shall be written as primary policies, not contributing with or in excess of coverage which Lessor may carry. 

E.2.      Notwithstanding anything to the contrary contained within this Article 11, Lessee’s
obligations to carry the insurance provided for herein may be brought within the coverage of a so-called blanket policy or policies of insurance carried and 

  
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maintained by Lessee, provided, however, that Lessor and Lessor’s first mortgagee or beneficiary shall be named as an additional insured thereunder as their interests may appear and that the
coverage afforded Lessor will not be reduced or diminished by reason of the use of such blanket policy insurance, and provided further that the requirements set forth herein are otherwise satisfied. Lessee agrees to permit Lessor at all reasonable
times to inspect any policies of insurance of Lessee which policies or copies thereof are not delivered to Lessor. 

E.3      If Lessor’s insurance rates for the Premises are increased at any time during the term as a
result of the nature of Lessee’s use and occupancy of the Premises, Lessee agrees to reimburse Lessor for the full amount of such increase immediately upon receipt of demand from Lessor thereof. Such increase shall be prorated as of the
expiration of the term, if applicable. 
 12.      MUTUAL WAIVER OF SUBROGATION RIGHTS: Lessor and
Lessee hereby waive any rights each may have against the other and Lessee hereby waives any rights it may have against any of the parties to the Agreement referred to in Article 10 on account of any loss or damage occasioned to Lessor or Lessee, as
the case may be, to their respective property, the premises, its contents or to other portions of the premises, arising from any risk generally covered by All Risk insurance; and the parties each, on behalf of their respective insurance companies
insuring the property of either Lessor or Lessee against any such loss, waive any right of subrogation that either may have against the other, as the case may be. Lessee, on behalf of its insurance companies insuring the premises, of its contents,
Lessee’s other property or other portions of the office building, waives any right of subrogation which such insurer or insurers may have against any of the parties to the Agreement. The foregoing waivers of subrogation shall be operative only
so long as available in the State where the office building is situated and provided further that no such policy is invalidated thereby. 

13.      Taxes: Lessee will pay before delinquency any and all taxes, assessments and license fees, and
public charges levied, assessed, or imposed and which become payable during the term hereof upon Lessee’s fixtures, furniture, and personal property installed or located in the Building. 

Lessee shall pay his/its pro rata share of any increase in the parking assessment fees, charges or bond amortization levied by the City of
Palo Alto or any other authorized or successor authority during the term of this lease. Lessee’s pro rata share shall be based upon the portion that Lessee’s Premises bears to the leased space of the entire building. 

Lessee shall be considered the owner during the term of any leasehold improvements installed at Lessee’s expense, and any such leasehold
improvements may be assessed to Lessee for property tax purposes. Except as otherwise provided in the Schedule, Lessee shall not remove from the Premises any leasehold improvements installed by Lessee without Lessor’s prior written consent, and
the ownership of any such leasehold improvements shall revert to Lessor upon the expiration of the term or upon sooner termination of the tenancy. 

14.      SERVICES: So long as Lessee is not in default hereunder, Lessor will furnish the Premises with
such services as are specified in the Schedule and Exhibit “D,” and Lessee will pay for all other services supplied to the Premises. Lessor shall not be liable to Lessee or to any other party for any claim, injury, damage, rebate, or
charge of any kind whatsoever which may arise or accrue in case of the interruption of the supply of water, heat, electricity, elevator service, air conditioning, gas, compressed air, or refrigeration caused by conditions beyond Lessor’s
control, or by accident, failure of power supply, repairs, strikes, fire, flood, act of God, or on account of any defect of the Building or the Premises, nor shall any such interruption be grounds for termination of this lease provided Lessor
exercises reasonable diligence to remedy such interruption. 
 15.      DESTRUCTION: In the event of a
partial destruction of the Building or appurtenances during the term from a cause which is insured under Lessor’s fire and extended coverage insurance, Lessor shall forthwith repair the same, provided such repairs can be made within ninety
(90) days under the laws and regulations of the state, county, federal, or municipal authorities, but such partial destruction shall not annul or void this lease, except that Lessee shall be entitled to a proportionate reduction of rent while
such repairs are being made, such proportionate reduction to be based upon the extent to which the making of repairs interferes with the business carried on by Lessee in the Premises. 

If the partial destruction is caused by a casualty which is not insured under Lessor’s fire and extended covered insurance or if such
repairs cannot be made in sixty (60) days, either Lessor or Lessee may terminate this lease by giving written notice to the other party within thirty (30) days after the damage occurs. If the lease is not terminated, Lessor shall make such
repairs within a reasonable time with this lease continuing in full force and effect and the rent proportionately reduced while the repairs are being made. 

In the event the Building in which the Premises are located is destroyed to the extent of not less than 33 1/3% of the then current
replacement cost thereof, Lessor may elect to terminate this lease by giving written notice of termination to Lessee within thirty (30) days after damage occurs, regardless of whether the Premises are damaged, whether the partial destruction is
caused by a casualty covered by insurance, or whether the repairs can be made within ninety (90) days. A total destruction of the Building in which the Premises are located shall terminate this lease. In respect to any partial destruction which
Lessor is obligated to repair or may elect to repair under the terms of this paragraph and which can be made within ninety (90) days the provisions of 

  
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Section 1932, Subdivision 2, and of Section 1933, Subdivision 4, of the Civil Code of the State of California are waived by Lessee. 

In the event of termination of this lease pursuant to any of the provisions of this paragraph, rent and Lessee’s portion of any parking
assessment fee increase shall be apportioned on a per diem basis and shall be paid to the date of the casualty. In no event shall Lessor be liable to Lessee for any damages resulting to Lessee from the happening of such casualty or from the
repairing or reconstruction of the Premises or of the Building, or from the termination of this lease as herein provided, nor shall Lessee be relieved thereby or in any such event from Lessee’s obligations hereunder except to the extent and
upon the conditions expressly stated in this paragraph. 
 16.      EMINENT DOMAIN: If the whole or any
substantial part of the Building or appurtenant real property shall be taken or condemned by any competent authority for any public use or purpose, the term of this lease shall end upon, and not before, the date when the possession of the part so
taken shall be required for such use or purpose. Rent shall be apportioned as of the date of such termination. Lessee shall be entitled to receive any damages awarded by the court for leasehold improvements installed at Lessee’s expense. The
entire balance of the award shall be the property of Lessor. 
 17.      ASSIGNMENT AND SUBLETTING:
Lessee shall not assign this lease, or any interest herein, and shall not sublet the Premises or any part thereof, or any right or privilege appurtenant thereto, or suffer any other person (the agents or employees of Lessee excepted) to occupy
or use the Premises, or any portion thereof, without the prior written consent of Lessor, and a consent to one assignment, subletting, occupation, or use by any other person shall not be deemed to be a consent to any subsequent assignment,
subletting, occupation, or use by any other person. Any such assignment or subletting without such consent shall be void, and shall, at the option of Lessor, terminate this lease. Any transfer or assignment of this lease by operation of law without
the consent of Lessor shall make this lease voidable at the option of Lessor. 
 Lessor will not unreasonably withhold its consent to an
assignment or subletting by Lessee, provided that (a) the assignee or sublessee is financially responsible and proposes to use the Premises for the same purpose or a purpose which is permitted by applicable zoning ordinances and regulations;
(b) the proposed use is not injurious to the Premises and will not disturb the other tenants of Lessor in the Building or immediate vicinity; and (c) the assignee or sublessee executes and delivers to Lessor a written assumption of this
lease in form acceptable to Lessor. 
 Every assignment of sublease shall recite that it is and shall be subject and subordinate to the
provisions of this lease, and the termination of this lease shall constitute a termination of every such assignment of sublease. 
 Lessor
agrees that Lessee may sublease all or a portion of the Premises to tenants reasonably acceptable to Lessor. Lessor and Lessee shall split any increase in sublease rent on a 50%/50% basis after Lessee first deducts its reasonable subleasing costs.

 18.      SUBORDINATION: The rights of Lessee under this lease shall be and they are subject and
subordinate at all times to the lien of any mortgage or deed of trust now or hereafter in force against the property, and to all advances made or hereafter to be made upon the security thereof, and Lessee shall execute such further instruments
subordinating this lease to the lien of any such encumbrance, as shall be requested by Lessor, provided the holder of such encumbrance agrees to recognize Lessee’s interest hereunder if Lessee is not then in default. Lessee hereby irrevocably
appoints Lessor as attorney in fact for Lessee with full power and authority to execute and deliver in the name of Lessee any such instrument. 

If any mortgagee or beneficiary elects to have this lease superior to its mortgage or deed of trust and gives notice of such fact to Lessee,
then this lease shall be deemed superior to the lien of any such encumbrance, whether this lease or a memorandum thereof is dated or recorded before or after said encumbrance. 

19.      SIGNS: Lessee shall not place any signs, lettering, marks, photographs, or any other material
whatsoever, on the interior or exterior of the doors, windows, hallways, or any other place, in, on, or about the Premises, the Building, or its appurtenances, without Lessor’s prior written approval of the size, style, design, color, material,
manner of applying of fastening, and location thereof. All signs shall be strictly in accordance with the Lessor’s Building standards and illuminated signs of any nature are prohibited. Lessee, at Lessee’s cost, shall be allowed to have
standard building signage, consistent with other Tenants in the Building including lobby directory and suite signage. 

20.      REMOVAL OF PROPERTY: Lessee hereby irrevocably appoints Lessor as agent and attorney in fact of
Lessee, to enter upon the Premises, in the event of default by Lessee in the payment of any rent herein reserved, or in the performance of any term, covenant, or condition herein contained to be kept or performed by Lessee, and to remove any and all
furniture and personal property whatsoever situated upon the Premises, and to place such property in storage for the account of and at the expense of Lessee. In the event that Lessee shall not pay the cost of storing any such property after the
property has been stored for a period of ninety (90) days or more, Lessor may sell any or all such property, at public or private sale, in such manner and at such times and places as Lessor in its sole discretion may deem proper, without notice
to Lessee or any demand upon Lessee for the payment of any part of such charges or the removal of any of such property, and shall apply the proceeds of such sale first to 

  
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the cost and expenses of such sale, including reasonable attorney’s fees actually incurred; second, to the payment of the costs of or charges for storing any such property; third, to the
payment of any other sums of money which may then or thereafter be due to Lessor from Lessee under any of the terms hereof; and fourth, the balance, if any, to Lessee. 

21.      SURRENDER: The voluntary or other surrender of this lease by Lessee, or a mutual cancellation
thereof, shall not work a merger, and shall, at the option of Lessor, terminate all or any existing subleases or subtenancies, or may, at the option of Lessor, operate as an assignment to Lessor of any or all such subleases or subtenancies. 

22.      TRANSFER OF SECURITY: Lessor may transfer or deliver any security given by Lessee to secure the
faithful performance of any of the covenants of this lease to the purchaser or successor of Lessor’s interest in the Premises, and thereupon Lessor shall be discharged from any further liability in reference thereto. 

23.      WAIVER: The waiver by Lessor or Lessee of any breach of any term, covenant, or condition herein
contained shall not be deemed to be a waiver of such term, covenant, or condition or and subsequent breach of the same or any other term, covenant, or condition herein contained. The subsequent acceptance of rent hereunder by Lessor shall not be
deemed to be a waiver of any preceding breach by Lessee at any term, covenant, or condition of this lease, other than the failure of Lessee to pay the particular rent so accepted, regardless of Lessor’s knowledge of such preceding breach at the
time of acceptance of such rent. 
 24.      HOLDING OVER: Any holding over after the expiration of the
term, with the consent of Lessor, shall be construed to be a tenancy from month to month on the same terms and conditions specified herein as far as applicable, except that the Base Rent will be 150% of Lessee’s current rental rate. 

25.      ATTORNEY’S FEES: If any action at law or in equity shall be brought to recover any rent
under this lease, or for or on account of any breach of or to enforce or interpret any of the terms, covenants, agreements, or conditions of this lease, or for the recovery of the possession of the Premises, the prevailing party shall be entitled to
recover from the other party as a part of the prevailing party’s costs a reasonable attorney’s fees and costs, the amount of which shall be fixed by the court and shall be made a part of any judgment rendered. 

26.      NOTICES: All notices to be given to Lessee may be given in writing personally, electronic mail
or by depositing the same in the United States mail, postage prepaid, and addressed to Lessee at the Premises, whether or not Lessee has departed from, abandoned, or vacated the Premises. Notice to Lessor may be given in writing personally,
electronic mail or by depositing the same in the United States mail, postage prepaid, and addressed to Lessor at the address to which the rent is paid. 

27.      GENERAL PROVISIONS: This lease contains all of the terms, covenants, and conditions agreed to by
Lessor and Lessee and it may not be modified orally or in any manner other than by an agreement in writing signed by all of the parties to this lease or their respective successors in interest. 

Each term and each provision of this lease performable by Lessee shall be construed to be both a covenant and a condition. 

The covenants and conditions hereof, subject to the provisions as to subletting and assignment, shall apply to and bind the heirs, successors,
executor, administrators, sublessees, and assigns of the parties. 
 All persons who have signed this lease shall be jointly and severally
liable hereunder. 
 When the context of this lease requires, the masculine gender includes the feminine, a corporation, or a partnership,
and the singular number includes the plural. 
 The captions of this lease are for convenience only and are not a part of this lease and do
not in any way limit or amplify the terms and provisions of this lease. 
 This lease shall be governed by and construed in accordance with
the laws of the State of California. 
 Time is of the essence as to all of the provisions of this lease. 

28.      RULES: The following rules and regulations in addition to those set forth in Exhibit
“C” hereof, relating to the safety, care and cleanliness of the Premises and the preservation of good order thereon, are hereby expressly made a part hereof, and Lessee agrees to obey all such rules and regulations. 

 A.      PEACEFUL ENJOYMENT:
Lessee, its employees, and visitors shall not interfere with the peaceful enjoyment of the Building by other lessees, if any, or those having business with them. Lessee shall not permit the placing of litter in or upon the Building and grounds
and shall not permit any animal, bicycle, motorcycle, or vehicle to be brought into or kept in the Building. Bicycle parking is provided in the basement only. 

B.      MOVING HEAVY OBJECTS: Lessee shall be responsible to repair any damage occasioned by the moving
of freight, furniture, or other objects into, within, or out of the Building. No heavy objects of any nature shall be placed upon any floor without Lessor’s prior written approval as to the adequacy of the allowable floor loading at the point
where the objects are intended to be moved or stored. Lessor may specify the time of moving to minimize inconvenience to other lessees, if any. 

C.      OBSTRUCTIONS, WASTE, MARKINGS: No drapes or sunscreens of any nature shall be installed without
Lessor’s prior approval. The sash doors, sashes, windows, glass doors, lights, and skylights that reflect or admit light into the 

  
 7 

 
Building shall not be covered or obstructed. The toilets and urinals shall not be used for any purpose other than those for which they were constructed, and no rubbish, newspapers or other
substances of any kind shall be thrown into them. Waste and excessive or unusual use of water shall not be allowed. Lessee shall not mark, drive nails, screw or drill into, paint, nor in any way deface any surface or part of the Building except that
Lessee may hang pictures, blackboards, or similar objects, providing that prior to end of the term Lessee shall restore the Premises to its condition at the commencement of the term, less reasonable wear and tear. The expense of repairing any
breakage, stoppage, or damage resulting from a violation of this rule shall be borne by the Lessee who has caused such breakage, stoppage, or damage. 

D.      LOCKS: No additional lock or locks shall be placed by Lessee on any door unless written consent
of Lessor shall first be obtained. Two keys shall be surrendered to Lessor upon termination or expiration of the lease term. 

E.      JANITORIAL SERVICES: If Lessor supplies janitorial services, Lessee shall not, without
Lessor’s prior consent, employ any person or persons, other than the janitor of Lessor, for the purposes of cleaning the leased Premises. Lessor shall not be responsible for the loss of property from the leased Premises, however occurring, or
for any damage to any Lessee occasioned by any of Lessee’s employees or subcontractors or by any other person. 

F.      OUTSIDE STORAGE: No materials, supplies, equipment, finished products, or semi-finished products,
raw materials, or articles of any nature shall be stored upon or permitted to remain on any portion of the leased Premises outside of the Building constructed thereon, except with the prior written consent of the Lessor. 

G.      OTHER RULES: Lessor reserves the right to make such other rules and regulations, including
parking regulations, as in Lessor’s judgment may from time to time be necessary for the safety, cleanliness, and orderly operation of the Premises. Lessee agrees to require its employees to abide by any such rules and regulations, including
parking regulations. 
 H.      RULES AND REGULATIONS: Lessee shall faithfully observe and comply with
the “Rules and Regulations,” a copy of which is attached hereto and marked Exhibit “C,” and those set forth herein above and all reasonable and nondiscriminatory modifications thereof and additions thereto from time to time put
into effect by Lessor. Lessor shall not be responsible to Lessee for the violation or non-performance by any other lessee or occupant of the Building of any of said Rules and Regulations. 

29.      DEFINITIONS: 

a) Commencement Date: The earlier of the following dates: 

(i) The date upon which the Lessee takes possession of or commences the operation of its business in the Premises. 

(ii) The date upon which the Leasehold Improvements have been substantially completed as determined by Lessor’s architect or
space planner (except that if completion of the Leasehold Improvements is delayed by Lessee’s design decisions, revisions, or additional work of Lessee or its agents, then the Commencement Date which would otherwise be established shall be
accelerated by the number of days of said delay). 
 30.      ANNUAL RENT INCREASE: 3% 

           Months 13-24: Base Rent is $9,298.33 

           Months 25-36: Base Rent is $9,577.27 

31.      LATE CHARGES: In the event Lessee fails to pay any installment of rent within three
(3) days when due or in the event Lessee fails to make any other payment to be made by it under this Lease when due, then Lessee shall pay to Lessor a late charge equal to five (5%) percent of the amount due to compensate Lessor for the
extra costs incurred as a result of such late payment. 
 32.      BROKERS: The parties recognize that
the brokers who negotiated this Lease are the brokers whose names are stated in Paragraph 1(N), and agree that Lessor shall be solely responsible for the payment of brokerage commissions to said brokers, and that Lessee shall have no responsibility
therefor. Lessee warrants that Lessee has not had any dealings with any realtor, broker, or agent, other than as specified in the Schedule hereto, in connection with negotiating or securing this lease. 

If Lessee has dealt with any other person or real estate broker with respect to leasing or renting space in the Building, Lessee shall be
solely responsible for the payment of any fee due said person or firm and Lessee shall hold Lessor free and harmless against any liability in respect thereto, including attorney’s fees and costs. 

33.      DAMAGE TO LESSEE’S PROPERTY: Lessor or its said agents shall not be liable for any damage
to property entrusted to employees of the Building, not for loss of or damage to any property by theft or otherwise, not for any injury or damage to persons or property resulting from fire, explosion, falling plaster, steam, gas, electricity, water
or rain which may leak 

  
 8 

 
from any part of the Building or from the pipes, appliances or plumbing works therein or from the roof, street or sub-surface or from any other place or resulting from dampness or any other cause
whatsoever. Lessor or its agents shall not be liable for interference with light or other incorporeal herediments, nor shall Lessor be liable for any latent defect in the Premises or in the Building. Lessee shall give prompt notice to Lessor in case
of fire or accidents in the Premises or in the Building or of defects therein or in the fixtures or equipment. 

34.      ESTOPPEL CERTIFICATE: 

(a)      Within ten (10) days following any written request which Lessor may make from time to time,
Lessee shall execute and deliver to Lessor a statement certifying: 
 (i) The date of commencement of this Lease; 

(ii) the fact that this lease is unmodified and in full force and effect (or, if there have been modifications hereto, that this lease
is in full force and effect, and stating the date and nature of such modifications); 
 (iii) the date to which the rental and other
sums payable under this lease have been paid. 
 (iv) that there are no current defaults under this lease by either Lessor or Lessee
except as specified in Lessee’s statement; and 
 (v) such other matters requested by Lessor. 

Lessor and Lessee intend that any statement delivered pursuant to this Paragraph 34 may be relied upon by any mortgage, beneficiary, purchaser or prospective
purchaser of the Building or any interest therein. 
 (b)      Lessee’s failure to deliver such
statement within such time shall be conclusive upon Lessee: 
 (i) That this lease is in full force and effect, without modification
except as may be represented by Lessor, 
 (ii) that there are no uncured defaults in Lessor’s performance, and 

(iii) that not more than one (1) month’s rental has been paid in advance. 

35.      MORTGAGE PROTECTION: In the event of any default on the part of Lessor, Lessee will give notice
by registered or certified mail to any beneficiary of a deed of trust or mortgage covering the Premises whose address shall have been furnished to Lessee, and shall offer such beneficiary or mortgagee a reasonable opportunity to cure the default,
including time to obtain possession of the Premises by power of sale or a judicial foreclosure, if such should prove necessary to effect a cure. 

36.      DEFINITION OF LESSOR: The term “Lessor” as used in this lease, so far as covenants or
obligations on the part of Lessor are concerned, shall be limited to mean and include only the owner or owners, at the time in question, of the fee title or any Lessees under ground lease, if any of the Premises. In the event of any such transfer,
assignment or other conveyance or transfer of any such title, Lessor’s herein named (and in case of any subsequent transfers or conveyances, the then grantor) shall be automatically freed and relieved from and after the date of such transfer,
assignment of conveyance of all liability as respects the performance of any covenants or obligations on the part of Lessor contained in this lease thereafter to be performed. Without further agreement, the transferee of such title shall be deemed
to have assumed and agreed to observe and perform any and all obligations of Lessor hereunder, during its ownership of the Premises. Lessor may transfer it interest in the Premises without the consent of Lessee and such transfer or subsequent
transfer shall not be deemed a violation on Lessor’s part of any of the terms and conditions of this lease. 

37.      INDEMNIFICATION OF LESSEE: If more than one person executes this Lease as Lessee: 

(a)      each of them is jointly and severally liable for the keeping, observing and performing of all of
the terms, covenants, conditions, provisions and agreements of this lease to be kept, observed and performed by Lessee, and 

(b)      the term “Lessee” as used in this lease shall mean and include each of them jointly
and severally. 
 The act of or notice from, or notice or refund to, or the signature of, any one or more of them, with respect to the tenancy of this
lease, including, but not limited to, any renewal, extension, expiration, termination or modification of this Lease, shall be binding upon each and all of the persons executing this lease as Lessee with the same force and effect as if each and all
of them had acted so given or received such notice or refund or so signed. 

  
 9 

 38.      AUTHORITY OF PARTIES: 

(a)      CORPORATE AUTHORITY. If Lessee is a corporation, each individual executing this Lease on behalf
of said corporation represents and warrants that he is duly authorized to execute and deliver this Lease on behalf of said corporation, in accordance with a duly adopted resolution of the board of directors of said corporation or in accordance with
the by-laws of said corporation in accordance with its terms. 
 (b)      LIMITED PARTNERSHIP. If the
Lessor herein is a limited partnership, it is understood and agreed that any claims by Lessee on Lessor shall be limited to the assets of the limited partnership, and furthermore, Lessee expressly waives any and all rights to proceeds against the
individual partners or the officers, directors or shareholders of any corporate partner, except to the extent of their interest in said limited partnership. 

39.      RIDERS: Clauses, plats and riders, if any, signed by Lessor and Lessee and affixed to this lease
are a part hereof. 
 40.      MODIFICATION FOR LENDER: If, in connection with obtaining construction,
interim or permanent financing for the Building, the lender shall request reasonable modifications in this lease as a condition to such financing, Lessee will not unreasonably withhold, delay or defer its consent thereto, provided that such
modifications do not increase the obligations of Lessee hereunder or materially adversely affect the leasehold interest hereby created or Lessee’s rights hereunder. 

41.      ACCORD AND SATISFACTION: No payment by Lessee or receipt by Lessor of a lesser amount than the
rent payment herein stipulated shall be deemed to be other than on account of the rent, nor shall any endorsement or statement on any check or any letter accompanying any check or payment as rent be deemed an accord and satisfaction, and Lessor may
accept such check or payment without prejudice to Lessor’s right to recover the balance of such rent or pursue any other remedy provided in this lease. 

Lessee agrees that each of the foregoing covenants and agreements shall be applicable to any covenant or agreement either expressly contained
in this lease or imposed by any statute or at common law. 
 42.      FINANCIAL STATEMENTS: At any time
during the term of this lease, Lessee shall, upon ten (10) days prior written notice from Lessor, provide Lessor with a current financial statement and financial statements of the two (2) years prior to the current financial statement
year. Such statement shall be prepared in accordance with generally accepted accounting principles and, if such is the normal practice of Lessee, shall be audited by an independent certified public accountant. 

43.      SEPARABILITY: Any provision of this lease which shall prove to be invalid, void or illegal in no
way affects, impairs or invalidates any other provisions hereof and such other provisions shall remain in full force and effect. 

44.      DEFAULTS AND REMEDIES: 

(a)      The occurrence of any one or more of the following events shall constitute a default hereunder by
Lessee: 
 (i) The abandonment of the Premises by Lessee. Abandonment is herein defined to include, but it is not limited to, any
absence by Lessee from the Premises for ten (10) days or longer while in default of any provision of this lease. 
 (ii) The
failure by Lessee to make any payment required to be made by Lessee hereunder, as and when due, where such failure shall continue for a period of three (3) days after written notice thereof from Lessor to Lessee; provided, however, that any
such notice shall be in lieu of, and not in addition to, any notice required under California Code of Civil Procedure Section 1161 regarding unlawful detainer actions. 

(iii) The failure by Lessee to observe or perform any of the express or implied covenants or provisions of this lease to be observed or
performed by Lessee, other than as specified in Subparagraph 44(a)(i) and (ii) above, where such failure shall continue for a period of ten (10) days after written notice thereof from Lessor to Lessee; provided, however, that any such
notice shall be in lieu of, and not in addition to, any notice required under California Code of Civil Procedure Section 1161 regarding unlawful detainer actions; provided, further, that if the nature of Lessee’s default is such that more
than ten (10) days are reasonably required of its cure, then Lessee shall not be deemed to be in default of Lessee shall commence such cure within said ten-day period and thereafter diligently prosecute such cure to completion, which completion
shall not occur later than sixty (60) days from the date of such notice from Lessor. 

(iv)            (1) The making by Lessee of any general assignment for
the benefit of creditors; 

  
 10 

 (2) the filing by or against Lessee of a petition to have Lessee adjudged a bankrupt or a
petition for reorganization or arrangement under any law relating to bankruptcy (unless, in the case of a petition filed against Lessee, the same is dismissed within thirty (30) days; 

(3) the appointment of a trustee or receiver to take possession of substantially all of Lessee’s assets located at the Premises
or of Lessee’s interest in this lease, where possession is not restored to Lessee within thirty (30) days; or 
 (4) the
attachment, execution or other judicial seizure of substantially all of Lessee’s assets located at the Premises or of Lessee’s interest in this Lease where such seizure is not discharged within thirty (30) days. 

(b)      In the event of any such default by Lessee, in addition to any other remedies available to
Lessor at law or in equity, Lessor shall have the option to immediately terminate this Lease and all rights of Lessee hereunder. In the event that Lessor shall elect to so terminate this Lease then Lessor may recover from Lessee: 

(i) The worth at the time of award of any unpaid rent which had been accrued at the time of such termination; plus 

(ii) the worth at the time of award of the amount by which the unpaid rent which would have been accrued after termination until the
time of award exceeds the amount of such rental loss that Lessee proves could have been reasonably avoided; plus 
 (iii) the worth
at the time of award of the amount by which the unpaid rent for the balance of the term after the time of award exceeds the amount of such rental loss that Lessee proves could be reasonably avoided; plus 

(iv) any other amount necessary to compensate Lessor for all the detriment proximately caused by Lessee’s failure to perform his
obligations under this lease or which in the ordinary course of things would be likely to result therefrom. 
 As used in Subparagraphs
44(b)(ii) above, the “worth at the time of award” is computed by allowing interest at the maximum rate permitted by law per annum. As used in Subparagraph 44(b)(iii) above, the “worth at the time of award” is computed by
discounting such amount at the discount rate of the Federal Reserve Bank of San Francisco at the time of award plus one (1%) percent. 

(c)      In the event of any default by Lessee, Lessor shall also have the right, with or without
terminating this lease, to re-enter the Premises and remove all persons and property from the Premises; such property may be removed and stored in a public warehouse or elsewhere at the cost of and for the account of this Subparagraph 44(c) shall be
construed as an election to terminate this lease unless a written notice of such intention to be given to Lessee unless the termination thereof be decreed by a court of competent jurisdiction. 

(d)      All rights, options, and remedies of Lessor contained in this lease shall be construed and held
to be cumulative, and no one of them shall be exclusive of the other, and Lessor shall have the right to pursue any one or all of such remedies or any other remedy or relief which may be provided by law, whether or not stated in this lease. No
waiver of any default of Lessee hereunder shall be implied from any acceptance by Lessor of any rent or other payments due hereunder or any omission by Lessor to take any action on account of such default if such default persists or is repeated, and
no express waiver shall affect defaults other than as specified in said waiver. The consent or approval of Lessor to or of any act by Lessee requiring Lessor’s consent or approval shall not be deemed to waive or render unnecessary Lessor’s
consent or approval to or of any subsequent similar acts by Lessee. 
 45.      RENEWAL OPTION:
Provided that Lessee is not in default under any of the terms, covenants or conditions of this lease at the conclusion of the initial term, Lessee shall have the option to renew this lease for an additional period of two (2) years
(hereinafter “extended term”) following the expiration of the original term upon giving written notice to Lessor not less than nine (9) months and not more than twelve (12) months before the expiration of the original term of
this lease of Lessee’s election to exercise this renewal option. The extended term shall be upon all of the terms and conditions contained in this lease, except that the base rent shall be at 100% of the fair market rent of comparable buildings
in the California Avenue district of Palo Alto and the NNN charges shall be at the prevailing NNN charge for the Complex. In no event shall the first (1st) year of the option period be less
than the last month’s rent of the initial lease term. 
 46.      PARKING: Lessee to have
exclusive use of one (1) marked and dedicated, underground parking stall at no charge throughout the lease term and any extension terms. 

  
 11 

 EXECUTED this
                     day of March, 2015, at
                    , of California. 
  

									
	LESSEE: Eiger BioPharmaceuticals, Inc.	 		 	LESSOR: JTC a California General Partnership
					
	By:	 	 /s/ David Cory
	 		 	By:	 	 /s/ Ray Tourzan

									
					
	Date:	 	 3-19-15
	 		 	Date:	 	 3-18-15

  
 12 

 EXHIBIT “A” 

OUTLINE OF TENANTS FLOOR PLAN 

Cambridge Place, 350 Cambridge Avenue, Palo Alto Ca. Suite 350 

 
 

 

  
 13 

 EXHIBIT “B” 

Leasehold Improvements 
 Lessor, at
Lessor’s sole cost, shall deliver the Premises with all building systems in good working order. Lessor shall perform the following improvements: 

a) Remove wooden crown moldings and other mutually agreed upon cabinetry / shelves. 

b) Remove wooden baseboards and replace with new building standard finishes 

c) Mutually agreed upon paint and carpet throughout 

d) Remove track lighting 
 e)
Replace any broken or stained ceiling tiles 
 Lessor-/s/ RT—(Initial) 

Lessee-/s/ DC—(Initial) 

  
 14 

 EXHIBIT “C” 

RULES AND REGULATIONS 
 1. No sign,
placard, picture, advertisement, name or notice shall be installed or displayed on any part of the outside or inside of the Building without the prior written consent of the Lessor. Lessor shall have the right to remove, at Lessee’s expense and
without notice, any sign installed or displayed in violation of this rule. All approved signs or lettering on doors and walls shall be printed, painted, affixed or inscribed at the expense of Lessee by a person chosen by Lessor. 

2. If Lessor objects in writing to any curtains, blinds, shades, screens or hanging plants or other similar objects attached to or used in connection with any
window or door of the Premises, Lessee shall immediately discontinue such use. No awning shall be permitted on any part of the Premises. Lessee shall not place anything against or near glass partitions or doors or windows which may appear unsightly
from outside the Premises. 
 3. Lessee shall not obstruct any sidewalks, halls, passages, exits, entrances, elevators, escalators, or stairways of the
Building. The halls, passages, exits, entrances, shopping malls, elevators, escalators and stairways are not open to the general public. Lessor shall in all cases retain the right to control and prevent access thereto of all persons whose presence
in the judgment of Lessor would be prejudicial to the safety, character, reputation and interest of the Building and its tenants; provided that nothing herein contained shall be construed to prevent such access to persons with whom any Lessee
normally deals in the ordinary course of its business, unless such persons are engaged in illegal activities. No Lessee and no employee or invitee of any Lessee shall go upon the roof of the Building. 

4. The directory of the Building will be provided exclusively for the display of the name and location of Tenants only and Lessor reserves the right to
exclude any other names therefrom. 
 5. All cleaning and janitorial services for the Building and the Premises shall be provided exclusively through
Lessor, and except with the written consent of Lessor, no person or persons other than those approved by Lessor shall be employed by Lessee or permitted to enter the Building for the purpose of cleaning the same. Lessee shall not cause any
unnecessary labor by carelessness or indifference to the good order and cleanliness of the Premises. Lessor shall not in any way be responsible to any Lessee for any loss of property on the Premises, however occurring, or for any damage to any
Lessee’s property by the janitor or any other employee or any other person. 
 6. Lessor will furnish Lessee, free of charge, with two keys to each
door lock in the Premises. Lessor may make a reasonable charge for any additional keys. Lessee shall not make or have made additional keys, and Lessee shall not alter any lock, or install a new additional lock or bolt on any door of its Premises.
Lessee, upon the termination of its tenancy, shall deliver to Lessor the keys of all doors which have been furnished to Lessee, and in the event of loss of any keys so furnished, shall pay Lessor thereafter. 

7. If Lessee requires telegraphic, telephonic, burglar alarm or similar services, it shall first obtain, and comply with, Lessor’s instructions in their
installation. 
 8. Any freight elevator shall be available for use by all tenants in the Building, subject to such reasonable scheduling as Lessor in its
discretion shall deem appropriate. No equipment, materials, furniture, packages, supplies, merchandise or other property will be received in the Building or carried in the elevators except between such hours and in such elevators as may be
designated by Lessor. 
 9. Lessee shall not place a load upon any floor of the Premises which exceeds the load per square foot which such floor was
designed to carry and which is allowed by law. Lessor shall have the right to prescribe the weight, size, and position of all equipment, materials, furniture or other property brought into the Building. Heavy objects shall, if considered necessary
by Lessor, stand on such platforms as determined by Lessor to be necessary to properly distribute the weight. Business machines and mechanical equipment belonging to Lessee, which cause noise or vibration that may be transmitted to the structure of
the Building or to any space therein to such a degree as to be objectionable to Lessor or to any tenants in the Building shall be placed and maintained by Lessee, at Lessee’s expense, on vibration eliminators or other devices sufficient to
eliminate noise or vibration. The persons employed to move such equipment in or out of the Building must be acceptable to Lessor. Lessor will not be responsible for loss of or damage to any such equipment or other property from any cause, and all
damage done to the Building by maintaining or moving such equipment or other property shall be repaired at the expense of Lessee. 
 10. Lessee shall not
use of keep in the Premises any kerosene, gasoline or other flammable or combustible fluid or material other than those limited quantities necessary for the operation or maintenance of office equipment. Lessee shall not use or permit to be used in
the Premises any foul or noxious gas or substance, or permit or allow the Premises to be occupied or used in a 

  
 15 

 
manner offensive or objectionable to Lessor or other occupants of the Building by reason of noise, odors, or vibrations, nor shall Lessee bring into or keep in or about the Premises any birds or
animals. 
 11. Lessee shall not use any method of heating or air-conditioning other than that supplied by Lessor. 

12. Lessee shall not waste electricity, water or air conditioning and agrees to cooperate fully with Lessor to assure the most effective operation of the
Building’s heating and air-conditioning and to comply with any governmental energy-saving rules, laws or regulations of which Lessee has actual notice, and shall refrain from adjusting controls. Lessee shall keep corridor doors closed, and
shall close window coverings at the end of each business day. 
 13. Lessor reserves the right to exclude from the Building between the hours of 6 p.m. and
7 a.m. the following day, or such other hours as may be established from time to time by Lessor, and on Sundays and legal holidays, any person unless that person is know to the person or employee in charge of the Building and has a pass or is
properly identified. Lessee shall be responsible for all persons for whom it requests passes and shall be liable to Lessor for all acts of such persons. Lessor shall not be liable for damages for any error with regard to the admission to or
exclusion from the Building of any person. Lessor reserves the right to prevent access to the Building in case of invasion, mob, riot, public excitement or other commotion by closing the doors or by other appropriate action. 

15. Lessee shall close and lock the doors of its Premises and entirely shut off all water faucets or other water apparatus, and electricity, gas or air
outlets before Lessee and its employees leave the Premises. Lessee shall be responsible for any damage or injuries sustained by other tenants or occupants of the Building or by Lessor for noncompliance with this rule. 

16. Lessee shall not obtain for use on the Premises ice, drinking water, food, beverage, towel or other similar services or accept barbering or bootblacking
service upon the Premises, except at such hours and under such regulations as may be fixed by Lessor. 
 17. The toilet rooms, toilets, urinals, wash bowls
and other apparatus shall not be used for any purpose other than that for which they were constructed and no foreign substance of any kind whatsoever shall be thrown therein. The expense of any breakage, stoppage or damage resulting from the
violation of this rule shall be borne by the Lessee who, or whose employees or invitees shall have caused. 
 18. Lessee shall not sell, or permit the sale
at retail, of newspapers, magazines, periodicals, theater tickets or any other goods or merchandise to the general public in or on the Premises. Lessee shall not make any room-to-room solicitation of business from other tenants in the Building.
Lessee shall not use the Premises for any business or activity other than that specifically provided for in Lessee’s Lease. 
 19. Lessee shall not
install any radio or television antenna, loudspeaker or other device on the roof or exterior walls of the Building. Lessee shall not interfere with radio or television broadcasting or reception from or in the Building or elsewhere. 

20. Lessee shall not mark, drive nails, screw or drill into the partitions, woodwork or plaster or in any way deface the Premises or any part thereof. Lessor
reserves the right to direct electricians as to where and how telephone and telegraph wires are to be introduced to the Premises. Lessee shall not cut or bore holes for wires. Lessee shall not affix any floor covering to the floor of the Premises in
any manner except as approved by Lessor. Lessee shall repair any damage resulting from noncompliance with this rule. 
 21. Lessee shall not install,
maintain or operate upon the Premises any vending machine without the written consent of Lessor. 
 22. Canvassing, soliciting and distribution of handbills
or any other written material, and peddling in the Building are prohibited, and each Lessee shall cooperate to prevent same. 
 23. Lessor reserves the
right to exclude or expel from the building any person who, in Lessor’s judgment, is intoxicated or under the influence of liquor or drugs or who is in violation of any of the Rules and Regulations of the Building. 

24. Lessee shall store all its trash and garbage within its Premises. Lessee shall not place in any trash box or receptacle any material which cannot be
disposed of in the ordinary and customary manner of trash and garbage disposal. All garbage and refuse disposal shall be made in accordance with directions issued from time to time by Lessor. 

25. The Premises shall not be used for lodging or for manufacturing of any kind, nor shall the Premises be used for any improper, immoral or objectionable
purpose. No cooking shall be done or permitted by any Lessee on the Premises, except that use by Lessee of Underwriter’s Laboratory approved equipment for brewing coffee, tea, hot chocolate and similar beverages shall be permitted, provided
that such equipment and use in accordance with all applicable federal, state, county and city laws, codes, ordinances rules and regulations. 

  
 16 

 26. Lessee shall not use in any space or in the public halls of the Building any hand trucks except those
equipped with rubber tires and side guards or such other material-handling equipment as Lessor may approve. Lessee shall not bring in any other vehicle of any kind into the Building. 

27. Without the written consent of Lessor, Lessee shall not use the name of the Building in connection with or in promoting or advertising the business of
Lessee except as Lessee’s address. 
 28. Lessee shall comply with all safety, fire protection and evacuation procedures and regulations established by
Lessor or any governmental agency. 
 29. Lessee assumes any and all responsibility for protecting its Premises from theft, robbery and pilferage, which
includes keeping doors locked and other means of entry to the Premises closed. 
 30. The requirements of Lessee will be attended to only upon appropriate
application to the office of the Building by an authorized individual. Employees of Lessor shall not perform any work or do anything outside of their regular duties unless under special instructions from Lessor, and no employee of Lessor will admit
any person (Lessee or otherwise) to any office without specific instructions from Lessor. 
 31. Lessor may waive any one or more of these rules and
Regulations for the benefit of Lessee or any other Lessee but no such waiver by Lessor shall be construed as a continuous waiver of such Rules and Regulations in favor of Lessee or any other Lessee, nor prevent Lessor from thereafter enforcing any
such Rules and Regulations against any or all of the tenants of the Building. 
 32. These Rules and Regulations are in addition to, and shall not be
construed to in any way modify or amend, in whole or in part, the terms, covenants, agreements and conditions of any lease of premises in the Building. 

33. Lessor reserves the right to make such other reasonable Rules and Regulations as, in its judgment, may from time to time be needed for safety and
security, for care and cleanliness of the Building and for preservation of good order therein. Lessee agrees to abide by all such Rules and Regulations hereinabove stated and any additional rules and regulations which are adopted. 

34. Lessee shall be responsible for the observance of all the foregoing rules by Lessee’s employees, agents, clients, customers, invitees and guests.

 Lessor-/s/ RT—(Initial) 

Lessee-/s/ DC—(Initial) 

  
 17 

 EXHIBIT “D” 

SERVICES PROVIDED BY LESSOR 
 The
following services will be provided by Lessor to Lessee at no additional cost, the Lessee will pay for its own electricity in the Premises: 
  

	 	1.	Five day a week janitorial service. 

  

	 	2.	Exterior and interior window washing (maximum two times per year.) 

  

	 	3.	Heating and air conditioning maintenance. (Operating times: Monday thru Friday 7AM to 7PM; Saturdays 8AM to 2PM). 

  

	 	4.	Elevator maintenance. 

  

	 	5.	Common area maintenance, including restrooms and atrium. 

  

	 	6.	Exterior building and room maintenance. 

 Lessor-/s/ RT—(Initial) 

Lessee-/s/ DC—(Initial) 

  
 18EX-10.39

 Exhibit 10.39 

December 5, 2008 
 Eiger Pharmaceuticals, Inc. 

2710 Sand Hill Road, Second Floor 
 Menlo Park, CA 94025 

David Cory 
 1541 Morse Blvd 

San Carlos, CA 94070 
  

	Re:	Employment Agreement 

 Dear David, 

Eiger BioPharmaceuticals, Inc. (“Company”) is pleased to offer you the position of President and Chief Executive Officer for the Company effective
January 2, 2009. 
 You will report to the Board of Directors and perform the duties customarily associated with your position at such place or places
as the Company shall reasonably designate, or as shall be reasonably appropriate and necessary in connection with such employment. 
 Your compensation will
be at an annualized rate of $320,000 per year less payroll deductions and standard withholdings. You will be paid semi-monthly in accordance with current Company policy. In addition you will be eligible to receive a bonus of up to 30% of base salary
based upon your performance and attainment of company objectives. This bonus will be earned and payable in the sole discretion of the Board of Directors and will be payable in cash, stock or stock options in the Board’s sole discretion. In
addition, you will receive a $50,000 one-time cash starting bonus payable on your first day of employment, less payroll deductions and standard withholdings. 

Per our Company policy, you’ll be eligible for the Company’s standard benefits package including medical, dental and vision insurance coverage in
the manner provided to other executive officers. You will be eligible to earn 15 days of vacation per calendar year, with rollover limitations consistent with Company policy. The Company may change compensation and benefits from time to time at its
discretion. 
 Subject to approval by the Compensation Committee of the Board of Directors, you will receive a stock option grant to purchase 6% of
outstanding shares immediately post Series A financing (expected to be 649,999), subject to the terms and conditions set forth in the Series A closing documents and the Company’s option plan (the “Option”). The effective vesting
commencement date for the option will be on your start date, and will vest 25% on the one year anniversary of your start date, and 1/36th per month thereafter, in each case subject to your
continued service, such that your option would be fully vested and exercisable on the fourth anniversary of the Start Date. The exercise price of your stock option will be equal to the fair market value of the Company’s Common Stock on the date
your option is approved by the board of directors. 

  
 Page 1 of 4 

 As a Company employee, you will be expected to abide by Company policies and procedures as they may be
interpreted, adopted, revised or deleted from time to time in the Company’s sole discretion. As a condition of employment, you will also be expected to promptly sign and comply with the attached Proprietary Information and Inventions Agreement.

 In your work for the Company, you will be expected not to make any unauthorized use or disclosure of any confidential information, including trade
secrets, of any former employer or other third party to whom you have an obligation of confidentiality. Rather, you will be expected to use only that information which is generally known and used by persons with training and experience comparable to
your own, which is common knowledge in the industry or otherwise legally in the public domain, or which is otherwise provided or developed by the Company. You agree that you will not bring onto Company premises any unpublished documents or property
belonging to any former employer or other third party to whom you have an obligation of confidentiality. You represent further that you have disclosed to the Company any contract you have signed that may restrict your activities on behalf of the
Company. As a condition of your employment, you will be required to provide proof of US citizenship or eligibility to work within the United States. 
 Your
employment relationship with the company is at-will. Thus, you may terminate your employment with the Company at any time and for any reason whatsoever simply by notifying the Company. Likewise, the Company may terminate your employment at any time,
with or without cause or advance notice. 
 In the event of A) your termination without cause or B) a Change of Control of the Company that
(i) requires a move of the company over 60 miles or (ii) results in a substantial reduction in your responsibilities or compensation within the first year of your employment: 

 

	 	a.	You will receive 6 months of your base salary, paid in the form of continuing base salary payments, less payroll deductions and standard withholdings 

 

	 	b.	Providing you elect COBRA in a timely manner, the Company will pay for your COBRA benefits for up to a maximum of 6 months or until you are enrolled in a separate benefits plan 

 

	 	c.	You will receive accelerated vesting of 100% of your unvested shares 

 In the event of A) your termination
without Cause or B) a Change of Control of the Company that (i) requires a move of the Company over 60 miles or (ii) results in a substantial reduction in your responsibilities or compensation after your first year of your employment: 

 

	 	a.	You will receive 12 months of your base salary, paid in the form of continuing base salary payments, less payroll deductions and standard withholdings. 

 

	 	b.	Providing you elect COBRA in a timely manner, the Company will pay for your COBRA benefits for up to a maximum of 12 months or until you are enrolled in a separate benefits plan in an amount not to exceed the
Company’s portion of your comparable pre-termination benefits. 

  
 Page 2 of 4 

	 	c.	You will receive accelerated vesting of 100% of your unvested shares 

 A “Change in Control” shall
mean any consolidation or merger of the Company with or into any other corporation or other entity or person, or any other corporate reorganization, in which the capital stock of the Company immediately prior to such consolidation, merger or
reorganization, represents less than 50% of the voting power of the surviving entity (or, if the surviving entity is a wholly owned subsidiary, its parent) immediately after such consolidation, merger or reorganization; or (B) any transaction
or series of related transactions to which the Company is a party in which in excess of fifty percent (50%) of the Company’s voting power is transferred; provided that a Change in Control shall not include (x) any consolidation or
merger effected exclusively to change the domicile of the Company, or (y) any transaction or series of transactions principally for bona fide equity financing purposes in which cash is received by the Company or indebtedness of the Company is
cancelled or converted or a combination thereof. A “Change of Control” shall also include insolvency, bankruptcy, or dissolution of the Company. 

“Cause” shall mean that in the reasonable determination of the Board, you commit any felony or crime involving moral turpitude, participate in any
fraud against the Company, willfully breach your duties to the Company, wrongfully disclose any trade secrets or other confidential information of the Company, or materially breach any material provision of the Agreement, the Proprietary Information
and Inventions Agreement or any other agreement entered into with the Company. 
 Please sign and date this letter and the enclosed Proprietary Information
and Inventions Agreement and return them to me by December 5, 2008 if you wish to accept employment under the terms described above. 
 Again let me
indicate how pleased we are to extend this offer and how much we at Eiger look forward to working with you. We look forward to your favorable reply and to a productive and enjoyable work relationship. 

 

	
	Sincerely,
	
	 /s/ Jeff Glenn

	 Officer
 Eiger BioPharmaceuticals,
Inc.

  
 Page 3 of 4 

	
	UNDERSTOOD AND AGREED:
	
	 /s/ David Cory

	David A. Cory, R.PH, MBA

  

			
	Date:	 	 12/12/08

  

			
	Start Date:	 	 1/2/08

  

			
	Attachment:	 	 Proprietary Information and Inventions Agreement

Release Agreement

  
 Page 4 of 4

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