Document:

EX-4.1

 Exhibit 4.1 

EXECUTION VERSION 
  

 
  

 
 ALERE INC., 

as Issuer, 
 the GUARANTORS named
herein, 
 as Guarantors, 
 and

 U.S. BANK NATIONAL ASSOCIATION, 

as Trustee 
  

 
 TWENTY-FIRST
SUPPLEMENTAL INDENTURE 
  
  

Dated as of June 24, 2015 
  

 
 6.375% Senior
Subordinated Notes due 2023 
  
  

 

 TABLE OF CONTENTS 

							
			
	 	 	 	  	Page	 
	ARTICLE ONE	  
		
	ESTABLISHMENT; DEFINITIONS AND INCORPORATION BY REFERENCE	  			
			
	 SECTION 1.01
	 	 Establishment
	  	 	2	  
	 SECTION 1.02
	 	 Definitions
	  	 	3	  
	 SECTION 1.03
	 	 Other Definitions
	  	 	34	  
	 SECTION 1.04
	 	 Incorporation by Reference of Trust Indenture Act
	  	 	35	  
	 SECTION 1.05
	 	 Rules of Construction
	  	 	35	  
	
	ARTICLE TWO	  
	
	THE NOTES	  
			
	 SECTION 2.01
	 	 Form and Dating
	  	 	36	  
	 SECTION 2.02
	 	 Execution, Authentication and Denomination; Additional Notes
	  	 	37	  
	 SECTION 2.03
	 	 Registrar and Paying Agent
	  	 	38	  
	 SECTION 2.04
	 	 Paying Agent to Hold Assets in Trust
	  	 	39	  
	 SECTION 2.05
	 	 Holder Lists
	  	 	39	  
	 SECTION 2.06
	 	 Transfer and Exchange
	  	 	39	  
	 SECTION 2.07
	 	 Replacement Notes
	  	 	40	  
	 SECTION 2.08
	 	 Outstanding Notes
	  	 	40	  
	 SECTION 2.09
	 	 Treasury Notes
	  	 	41	  
	 SECTION 2.10
	 	 Temporary Notes
	  	 	41	  
	 SECTION 2.11
	 	 Cancellation
	  	 	41	  
	 SECTION 2.12
	 	 Defaulted Interest
	  	 	42	  
	 SECTION 2.13
	 	 CUSIP and ISIN Numbers
	  	 	42	  
	 SECTION 2.14
	 	 Deposit of Moneys
	  	 	42	  
	 SECTION 2.15
	 	 Book-Entry Provisions for Global Notes
	  	 	42	  
	 SECTION 2.16
	 	 Special Transfer and Exchange Provisions.
	  	 	44	  
	
	ARTICLE THREE	  
	
	REDEMPTION	  
			
	 SECTION 3.01
	 	 Notices to Trustee
	  	 	48	  
	 SECTION 3.02
	 	 Selection of Notes to be Redeemed
	  	 	48	  
	 SECTION 3.03
	 	 Notice of Redemption
	  	 	48	  
	 SECTION 3.04
	 	 Effect of Notice of Redemption
	  	 	49	  
	 SECTION 3.05
	 	 Deposit of Redemption Price
	  	 	50	  
	 SECTION 3.06
	 	 Notes Redeemed in Part
	  	 	50	  

  
 -i- 

							
	 	 	 	  	Page	 
	ARTICLE FOUR	  
	
	COVENANTS	  
			
	 SECTION 4.01
	 	 Payment of Principal and Interest
	  	 	50	  
	 SECTION 4.02
	 	 Maintenance of Office or Agency
	  	 	51	  
	 SECTION 4.03
	 	 Corporate Existence
	  	 	51	  
	 SECTION 4.04
	 	 Compliance Certificate
	  	 	51	  
	 SECTION 4.05
	 	 Waiver of Stay, Extension or Usury Laws
	  	 	53	  
	 SECTION 4.06
	 	 Change of Control
	  	 	53	  
	 SECTION 4.07
	 	 Limitations on Additional Indebtedness
	  	 	55	  
	 SECTION 4.08
	 	 Limitations on Restricted Payments
	  	 	59	  
	 SECTION 4.09
	 	 Limitations on Liens
	  	 	62	  
	 SECTION 4.10
	 	 Limitations on Asset Sales
	  	 	62	  
	 SECTION 4.11
	 	 Limitations on Transactions with Affiliates
	  	 	66	  
	 SECTION 4.12
	 	 Limitations on Dividends and Other Restrictions Affecting Restricted Subsidiaries
	  	 	68	  
	 SECTION 4.13
	 	 Additional Guarantees
	  	 	70	  
	 SECTION 4.14
	 	 Limitation on Layering Indebtedness
	  	 	70	  
	 SECTION 4.15
	 	 SEC Reports
	  	 	71	  
	 SECTION 4.16
	 	 Limitations on Designation of Unrestricted Subsidiaries
	  	 	72	  
	 SECTION 4.17
	 	 Conduct of Business
	  	 	73	  
	 SECTION 4.18
	 	 Limitations on Sale and Leaseback Transactions
	  	 	73	  
	 SECTION 4.19
	 	 Suspension of Covenants
	  	 	73	  
		
	ARTICLE FIVE	  			
		
	SUCCESSOR CORPORATION	  			
			
	 SECTION 5.01
	 	 Mergers, Consolidations, Etc
	  	 	75	  
	
	ARTICLE SIX	  
	
	DEFAULT AND REMEDIES	  
			
	 SECTION 6.01
	 	 Events of Default
	  	 	77	  
	 SECTION 6.02
	 	 Acceleration
	  	 	79	  
	 SECTION 6.03
	 	 Other Remedies
	  	 	80	  
	 SECTION 6.04
	 	 Waiver of Past Defaults
	  	 	80	  
	 SECTION 6.05
	 	 Control by Majority
	  	 	80	  
	 SECTION 6.06
	 	 Limitation on Suits
	  	 	80	  
	 SECTION 6.07
	 	 Rights of Holders to Receive Payment
	  	 	81	  

  
 -ii- 

							
	 	 	 	  	Page	 
	 SECTION 6.08
	 	 Collection Suit by Trustee
	  	 	81	  
	 SECTION 6.09
	 	 Trustee May File Proofs of Claim
	  	 	81	  
	 SECTION 6.10
	 	 Priorities
	  	 	82	  
	 SECTION 6.11
	 	 Undertaking for Costs
	  	 	82	  
	
	ARTICLE SEVEN	  
	
	TRUSTEE	  
			
	 SECTION 7.01
	 	 Duties of Trustee
	  	 	82	  
	 SECTION 7.02
	 	 Rights of Trustee
	  	 	83	  
	 SECTION 7.03
	 	 Individual Rights of Trustee
	  	 	85	  
	 SECTION 7.04
	 	 Trustee’s Disclaimer
	  	 	85	  
	 SECTION 7.05
	 	 Notice of Default
	  	 	85	  
	 SECTION 7.06
	 	 Reports by Trustee to Holders
	  	 	85	  
	 SECTION 7.07
	 	 Compensation and Indemnity
	  	 	86	  
	 SECTION 7.08
	 	 Replacement of Trustee
	  	 	87	  
	 SECTION 7.09
	 	 Successor Trustee by Merger, Etc
	  	 	88	  
	 SECTION 7.10
	 	 Eligibility; Disqualification
	  	 	88	  
	 SECTION 7.11
	 	 Preferential Collection of Claims Against the Issuer
	  	 	88	  
	
	ARTICLE EIGHT	  
	
	DISCHARGE OF INDENTURE; DEFEASANCE	  
			
	 SECTION 8.01
	 	 Termination of the Issuer’s Obligations
	  	 	88	  
	 SECTION 8.02
	 	 Legal Defeasance and Covenant Defeasance
	  	 	89	  
	 SECTION 8.03
	 	 Conditions to Legal Defeasance or Covenant Defeasance
	  	 	91	  
	 SECTION 8.04
	 	 Application of Trust Money
	  	 	92	  
	 SECTION 8.05
	 	 Repayment to the Issuer
	  	 	92	  
	 SECTION 8.06
	 	 Reinstatement
	  	 	93	  
	
	ARTICLE NINE	  
	
	AMENDMENTS, SUPPLEMENTS AND WAIVERS	  
			
	 SECTION 9.01
	 	 Without Consent of Holders
	  	 	93	  
	 SECTION 9.02
	 	 With Consent of Holders
	  	 	94	  
	 SECTION 9.03
	 	 Effect on Senior Debt
	  	 	95	  
	 SECTION 9.04
	 	 Compliance with the Trust Indenture Act
	  	 	96	  
	 SECTION 9.05
	 	 Revocation and Effect of Consents
	  	 	96	  
	 SECTION 9.06
	 	 Notation on or Exchange of Notes
	  	 	96	  
	 SECTION 9.07
	 	 Trustee To Sign Amendments, Etc
	  	 	97	  

  
 -iii- 

							
	 	 	 	  	Page	 
	
	ARTICLE TEN	  
	
	SUBORDINATION OF NOTES	  
			
	 SECTION 10.01
	 	 Notes Subordinated to Senior Debt
	  	 	97	  
	 SECTION 10.02
	 	 Suspension of Payment When Senior Debt Is in Default
	  	 	98	  
	 SECTION 10.03
	 	Notes Subordinated to Prior Payment of All Senior Debt on Dissolution, Liquidation or Reorganization of the Issuer	  	 	99	  
	 SECTION 10.04
	 	 Payments May Be Made on Notes
	  	 	100	  
	 SECTION 10.05
	 	 Holders To Be Subrogated to Rights of Holders of Senior Debt
	  	 	101	  
	 SECTION 10.06
	 	 Obligations of the Issuer Unconditional
	  	 	101	  
	 SECTION 10.07
	 	 Notice to Trustee
	  	 	101	  
	 SECTION 10.08
	 	 Reliance on Judicial Order or Certificate of Liquidating Agent
	  	 	102	  
	 SECTION 10.09
	 	 Trustee’s Relation to Senior Debt
	  	 	102	  
	 SECTION 10.10
	 	 Subordination Rights Not Impaired by Acts or Omissions of the Issuer or Holders of Senior Debt
	  	 	102	  
	 SECTION 10.11
	 	 Holders Authorize Trustee To Effectuate Subordination of Notes
	  	 	103	  
	 SECTION 10.12
	 	 This Article Ten Not To Prevent Events of Default
	  	 	103	  
	 SECTION 10.13
	 	 Trustee’s Compensation Not Prejudiced
	  	 	103	  
	
	ARTICLE ELEVEN	  
	
	GUARANTEE	  
			
	 SECTION 11.01
	 	 Unconditional Guarantee
	  	 	104	  
	 SECTION 11.02
	 	 Subordination of Guarantee
	  	 	105	  
	 SECTION 11.03
	 	 Limitation on Guarantor Liability
	  	 	105	  
	 SECTION 11.04
	 	 Release of a Guarantor
	  	 	106	  
	 SECTION 11.05
	 	 Waiver of Subrogation
	  	 	106	  
	 SECTION 11.06
	 	 Immediate Payment
	  	 	107	  
	 SECTION 11.07
	 	 No Set-Off
	  	 	107	  
	 SECTION 11.08
	 	 Guarantee Obligations Absolute
	  	 	107	  
	 SECTION 11.09
	 	 Guarantee Obligations Continuing
	  	 	107	  
	 SECTION 11.10
	 	 Guarantee Obligations Not Reduced
	  	 	107	  
	 SECTION 11.11
	 	 Guarantee Obligations Reinstated
	  	 	108	  
	 SECTION 11.12
	 	 Guarantee Obligations Not Affected
	  	 	108	  
	 SECTION 11.13
	 	 Waiver; Reliance
	  	 	109	  
	 SECTION 11.14
	 	 No Obligation To Take Action Against the Issuer
	  	 	109	  
	 SECTION 11.15
	 	 Dealing with the Issuer and Others
	  	 	110	  
	 SECTION 11.16
	 	 Default and Enforcement
	  	 	110	  
	 SECTION 11.17
	 	 Amendment, Etc
	  	 	110	  

  
 -iv- 

							
	 	 	 	  	Page	 
	 SECTION 11.18
	 	 Acknowledgment
	  	 	110	  
	 SECTION 11.19
	 	 Costs and Expenses
	  	 	111	  
	 SECTION 11.20
	 	 No Waiver; Cumulative Remedies
	  	 	111	  
	 SECTION 11.21
	 	 Survival of Guarantee Obligations
	  	 	111	  
	 SECTION 11.22
	 	 Guarantee in Addition to Other Guarantee Obligations
	  	 	111	  
	
	ARTICLE TWELVE	  
	
	MISCELLANEOUS	  
			
	 SECTION 12.01
	 	 Trust Indenture Act Controls
	  	 	111	  
	 SECTION 12.02
	 	 Notices
	  	 	111	  
	 SECTION 12.03
	 	 Communications by Holders with Other Holders
	  	 	113	  
	 SECTION 12.04
	 	 Certificate and Opinion as to Conditions Precedent
	  	 	113	  
	 SECTION 12.05
	 	 Statements Required in Certificate or Opinion
	  	 	113	  
	 SECTION 12.06
	 	 Rules by Trustee and Agents
	  	 	114	  
	 SECTION 12.07
	 	 Legal Holidays
	  	 	114	  
	 SECTION 12.08
	 	 Governing Law; Waiver of Jury Trial
	  	 	114	  
	 SECTION 12.09
	 	 No Adverse Interpretation of Other Agreements
	  	 	114	  
	 SECTION 12.10
	 	 No Recourse Against Others
	  	 	114	  
	 SECTION 12.11
	 	 Successors
	  	 	115	  
	 SECTION 12.12
	 	 Duplicate Originals
	  	 	115	  
	 SECTION 12.13
	 	 Severability
	  	 	115	  
	 SECTION 12.14
	 	 Force Majeure
	  	 	115	  
	 SECTION 12.15
	 	 U.S.A. Patriot Act
	  	 	115	  

 Exhibits 
  

			
	 Exhibit A
	  	 Form of Note

	 Exhibit B
	  	 Forms of Legends

	 Exhibit C
	  	 Form of Certificate to be delivered in connection with Transfers to Non-QIB Institutional Accredited Investors

	 Exhibit D
	  	 Form of Certificate to be delivered in connection with Transfers pursuant to Regulation S

	 Exhibit E
	  	 Form of Supplemental Indenture

  
 -v- 

 CROSS-REFERENCE TABLE 

 

			
	 Trust Indenture Act Section
	  	 Indenture Section

	§ 310(a)(1)	  	7.10
	(a)(2)	  	7.10
	(a)(3)	  	Not Applicable
	(a)(4)	  	Not Applicable
	(a)(5)	  	7.10
	(b)	  	7.08; 7.10
		
	311(a)	  	7.11
	(b)	  	7.11
		
	312(a)	  	2.05
	(b)	  	12.03
	(c)	  	12.03
	313(a)	  	7.06
	(b)(1)	  	Not Applicable
	(b)(2)	  	7.06
	(c)	  	12.02
	(d)	  	7.06
	314(a)	  	4.15; 12.02
	(b)	  	Not Applicable
	(c)(1)	  	12.04
	(c)(2)	  	12.04
	(c)(3)	  	Not Applicable
	(d)	  	Not Applicable
	(e)	  	12.05
	(f)	  	Not Applicable
	315(a)	  	7.01
	(b)	  	7.05; 12.02
	(c)	  	7.01
	(d)	  	7.01
	(e)	  	6.11
	316(a)(1)(A)	  	6.05
	(a)(1)(B)	  	6.04
	(a)(2)	  	Not Applicable
	(a)(last sentence)	  	2.09
	(b)	  	6.07; 9.02
	(c)	  	9.05
	317(a)(1)	  	6.08
	(a)(2)	  	6.09
	(b)	  	2.04
	318(a)	  	12.01

  
 Note: This
Cross-Reference Table shall not, for any purpose, be deemed to be a part of this Indenture. 

 TWENTY-FIRST SUPPLEMENTAL INDENTURE, dated as of June 24, 2015 (this “Supplemental
Indenture”), among Alere Inc. (formerly Inverness Medical Innovations, Inc.), a Delaware corporation, as Issuer (the “Issuer”), each of the Guarantors named herein, as Guarantors, and U.S. Bank National Association, a
national banking association, as Trustee (the “Trustee”). 
 THIS INDENTURE WITNESSETH 

WHEREAS, the Issuer and the Trustee have previously executed and delivered an Indenture, dated as of May 12, 2009 (the “Base
Indenture”), providing for the issuance from time to time of one or more series of the debt securities of the Issuer; 
 WHEREAS,
Sections 2.01, 2.02 and 9.01 of the Base Indenture provide that the Issuer and the Trustee may enter into an indenture supplemental to the Base Indenture to establish the form or terms of a series of securities; 

WHEREAS, the Issuer has duly authorized the creation and issue of 6.375% Senior Subordinated Notes due 2023 and, to provide therefor, the
Issuer and the Guarantors have duly authorized the execution and delivery of this Supplemental Indenture; 
 WHEREAS, the Issuer is entering
into this Supplemental Indenture to establish the form and terms of such 6.375% Senior Subordinated Notes due 2023; 
 WHEREAS, the Base
Indenture is incorporated in this Supplemental Indenture by reference as set forth in this Supplemental Indenture, and the Base Indenture, as amended, supplemented and modified by this Supplemental Indenture and as may be further amended,
supplemented or modified with respect to this Supplemental Indenture, is referred to as this “Indenture” in this Supplemental Indenture; and 

WHEREAS, all conditions precedent to be performed or effected by the Issuer and the Guarantors to authorize the execution and delivery of this
Supplemental Indenture and to make it the valid and binding obligations of the Issuer and the Guarantors, as applicable, have been complied with; 

NOW THEREFORE, each party agrees as follows for the benefit of the other parties and for the equal and ratable benefit of the Holders of the
Notes (each as defined below): 
 ARTICLE ONE 

ESTABLISHMENT; DEFINITIONS AND INCORPORATION BY REFERENCE 

SECTION 1.01 Establishment. 
 (a)
There is hereby established a new Series of Securities (each as defined in the Base Indenture) to be issued under this Indenture, designated as the Issuer’s 6.375% Senior Subordinated Notes due 2023. 

  
 -2- 

 (b) There are to be authenticated and delivered on the date hereof up to $425,000,000 aggregate
principal amount of the Notes. 
 (c) The Notes shall be issued in the form of one or more permanent Notes in accordance with Article Two of
this Supplemental Indenture. 
 (d) Each Note shall be dated the date of authentication thereof and shall bear interest from the date of
original issuance thereof (which, in the case of the Initial Notes, is the Issue Date) or from the most recent date to which interest has been paid or duly provided for on the applicable Notes, all as further provided in this Supplemental Indenture.

 (e) Solely with respect to the Notes and the Guarantees, the Base Indenture shall be amended, supplemented and modified pursuant to
Sections 2.01, 2.02 and 9.01 thereof to establish the terms of the Notes and the Guarantees as set forth in this Supplemental Indenture, including as follows: 

(1) the form and terms of the securities representing the Notes required to be established pursuant to Article Two of the Base
Indenture are established pursuant to Article Two of this Supplemental Indenture; 
 (2) the provisions of Articles One, Two,
Three, Four, Five, Six, Seven, Eight, Nine and Ten of the Base Indenture are superseded in their entirety by, respectively, the provisions of Articles One, Two, Three, Four, Five, Six, Seven, Eight, Nine and Twelve of this Supplemental Indenture;

 (3) the provisions of Articles Ten and Eleven of this Supplemental Indenture supplement, but shall not otherwise modify,
the Base Indenture (as otherwise supplemented by this Supplemental Indenture); 
 (4) to the extent that the provisions of
this Supplemental Indenture (including those referred to in clauses (2) and (3) immediately above) are duplicative of, or in conflict with, any provision of the Base Indenture, the provisions of this Supplemental Indenture shall govern and
be controlling; 
 (5) Article Eleven of the Base Indenture is deleted in its entirety for purposes of this Supplemental
Indenture; and 
 (6) unless otherwise expressly specified, references in this Supplemental Indenture to specific Article or
Section numbers refer to Articles and Sections contained in this Supplemental Indenture, and not the Base Indenture or any other document. 

SECTION 1.02 Definitions. 
 Set forth
below are certain defined terms used in this Indenture. 
 “2007 Convertible Notes” means those certain 3% convertible
senior subordinated notes due 2016 in the aggregate principal amount of $150.0 million issued by the Issuer to certain holders thereof under that certain Indenture between the Issuer and U.S. Bank National Association, as trustee, dated as of
May 14, 2007. 

  
 -3- 

 “2010 Senior Subordinated Notes” means those certain 8.625% senior subordinated
notes due 2018 issued by the Issuer to certain holders thereof under the 2010 Senior Subordinated Notes Indenture. 
 “2010 Senior
Subordinated Notes Indenture” means that certain Indenture between the Issuer and U.S. Bank National Association, as trustee, dated as of May 12, 2009, as amended, supplemented and modified by that certain Ninth Supplemental Indenture
among the Issuer, the guarantors named therein and U.S. Bank National Association, as trustee, dated as of September 21, 2010, as the foregoing has been further amended, supplemented and modified to date and may be further amended, supplemented
and modified. 
 “2013 Senior Subordinated Notes” means those certain 6.500% senior subordinated notes due 2020 issued by
the Issuer to certain holders thereof under the 2013 Senior Subordinated Notes Indenture. 
 “2013 Senior Subordinated Notes
Indenture” means that certain Indenture between the Issuer and U.S. Bank National Association, as trustee, dated as of May 12, 2009, as amended, supplemented and modified by that certain Sixteenth Supplemental Indenture among the
Issuer, the guarantors named therein and U.S. Bank National Association, as trustee, dated as of May 24, 2013, as further amended, supplemented and modified to date and as may be further amended, supplemented and modified. 

“Acquired Indebtedness” means (1) with respect to any Person that becomes a Restricted Subsidiary after the Issue Date,
Indebtedness of such Person and its Subsidiaries existing at the time such Person becomes a Restricted Subsidiary that was not incurred in connection with, or in contemplation of, such Person becoming a Restricted Subsidiary and (2) with
respect to the Issuer or any Restricted Subsidiary, any Indebtedness of a Person (other than the Issuer or a Restricted Subsidiary) existing at the time such Person is merged with or into, or consolidated with, the Issuer or a Restricted Subsidiary,
or Indebtedness expressly assumed by the Issuer or any Restricted Subsidiary in connection with the acquisition of any Person or any asset or assets from another Person, which Indebtedness was not, in any case, incurred by such other Person in
connection with, or in contemplation of, such merger, consolidation or acquisition. 
 “Affiliate” of any Person means any
other Person which directly or indirectly controls or is controlled by, or is under direct or indirect common control with, the referent Person. For purposes of Section 4.11, Affiliates shall be deemed to include, with respect to any Person,
any other Person (1) which beneficially owns or holds, directly or indirectly, 10% or more of any class of the Voting Stock of the referent Person, (2) of which 10% or more of the Voting Stock is beneficially owned or held, directly or
indirectly, by the referenced Person or (3) with respect to an individual, any immediate family member of such Person. For purposes of this definition, “control” of a Person shall mean the power to direct the management and
policies of such Person, directly or indirectly, whether through the ownership of voting securities, by contract or otherwise, and “controlling,” “controlled by” and “under common control” shall
have correlative meanings. 

  
 -4- 

 “Agent” means any Registrar or Paying Agent. 

“amend” means to amend, supplement, restate, amend and restate or otherwise modify; and “amendment” shall
have a correlative meaning. 
 “asset” means any asset or property. 

“Asset Acquisition” means: 

(1) an Investment by the Issuer or any Restricted Subsidiary of the Issuer in any other Person if, as a result of such Investment, such Person
shall become a Restricted Subsidiary of the Issuer, or shall be merged with or into the Issuer or any Restricted Subsidiary of the Issuer; or 

(2) the acquisition by the Issuer or any Restricted Subsidiary of the Issuer of all or substantially all of the assets of any other Person or
any division or line of business of any other Person. 
 “Asset Sale” means any sale, conveyance, transfer, lease,
assignment, license or other disposition on or after the Issue Date by the Issuer or any Restricted Subsidiary to any Person other than the Issuer or any Restricted Subsidiary (including by means of a Sale and Leaseback Transaction or a merger or
consolidation) (collectively, for purposes of this definition, a “transfer”), in one transaction or a series of related transactions, of any assets of the Issuer or any of its Restricted Subsidiaries other than in the ordinary
course of business. For purposes of this definition, the term “Asset Sale” shall not include: 
 (1) transfers of cash or Cash
Equivalents; 
 (2) transfers of assets (including Equity Interests) that are governed by, and made in accordance with, Article Five; 

(3) Permitted Investments, Restricted Payments permitted under Section 4.08 and transfers that would constitute Restricted Payments but
for the exclusions in clauses (1) and (2) of the definition thereof; 
 (4) the creation or realization of any Permitted Lien;

 (5) transfers of damaged, worn-out or obsolete equipment or assets that, in the Issuer’s reasonable judgment, are no longer used or
useful in the business of the Issuer or the Restricted Subsidiaries; 
 (6) any license of intellectual property not otherwise in the
ordinary course of business, other than the license of all or substantially all of the rights associated with any intellectual property owned or controlled by the Issuer or any of the Restricted Subsidiaries if (i) such rights are used or could
be used in a line of business then being conducted by the Issuer or any of the Restricted Subsidiaries and such rights and line of business are material to the 

  
 -5- 

 
business of the Issuer and the Restricted Subsidiaries taken as a whole, as reasonably determined by the Issuer, (ii) such license is for all or substantially all of the remaining
contractual or useful life of such intellectual property, whichever is shorter, determined as of the date such license is granted, and (iii) the Fair Market Value of such license, together with that of any other such licenses meeting the
criteria in clauses (i) and (ii) (with the Fair Market Value of any such license being determined at the time thereof and without regard to subsequent changes in value), exceeds $25.0 million in any fiscal year of the Issuer; and 

(7) any transfer or series of related transfers that, but for this clause, would be Asset Sales, if after giving effect to such transfers, the
aggregate Fair Market Value of the assets transferred in such transaction or any such series of related transactions does not exceed, in the aggregate with all other such transactions or series of related transactions (with the Fair Market Value of
any such transaction being determined at the time thereof and without regard to subsequent changes in value), $25.0 million in any fiscal year of the Issuer. 

“Attributable Indebtedness,” when used with respect to any Sale and Leaseback Transaction, means, as at the time of
determination, the present value (discounted at a rate equivalent to the Issuer’s then-current weighted average cost of funds for borrowed money as at the time of determination, compounded on a semi-annual basis) of the total obligations of the
lessee for rental payments during the remaining term of the lease included in any such Sale and Leaseback Transaction. 

“Bankruptcy Law” means Title 11 of the United States Code, as amended, or any similar federal or state law for the relief of
debtors. 
 “Board of Directors” shall mean, with respect to any Person, (i) in the case of any corporation, the board
of directors of such Person, (ii) in the case of any limited liability company, the board of managers of such Person, (iii) in the case of any partnership, the Board of Directors of the general partner of such Person and (iv) in any
other case, the functional equivalent of the foregoing, or any committee thereof duly authorized to act on behalf of such Board. 

“Business Day” means a day other than a Saturday, Sunday or other day on which banking institutions in The City of New York,
New York are authorized or required by law to close. 
 “Capitalized Lease” means a lease required to be capitalized for
financial reporting purposes in accordance with GAAP. 
 “Capitalized Lease Obligations” of any Person means the
obligations of such Person to pay rent or other amounts under a Capitalized Lease, and the amount of such obligations shall be the capitalized amount thereof determined in accordance with GAAP. 

“Cash Equivalents” means: 

(1) marketable obligations with a maturity of one (1) year or less issued or directly and fully guaranteed or insured by the
United States of America or issued by any agency or instrumentality thereof and the full faith and credit of the United States of America is pledged in support thereof; 

  
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 (2) any marketable direct obligations issued by any other agency of the United States of America,
any State of the United States of America or the District of Columbia, or any political subdivision of any such state or instrumentality thereof, in each case having one of the two highest ratings obtainable from either S&P or Moody’s; 

(3) demand and time deposits and certificates of deposit or acceptances with a maturity of one hundred eighty (180) days or less of any
financial institution that is a member of the Federal Reserve System having combined capital and surplus and undivided profits of not less than $500.0 million; 

(4) commercial paper maturing no more than one (1) year from the date of creation thereof issued by a corporation that is not the Issuer
or an Affiliate of the Issuer, and is organized under the laws of any State of the United States of America or the District of Columbia and rated at least A-1 by S&P or at least P-1 by Moody’s; 

(5) repurchase obligations with a term of not more than ten (10) days for underlying securities of the types described in clause
(1) above entered into with any commercial bank meeting the specifications of clause (3) above; 
 (6) investments in money market
or other mutual funds substantially all of whose assets comprise securities of the types described in clauses (1) through (5) above; and 

(7) other short-term investments utilized by any Foreign Subsidiary in accordance with normal investment practices for cash management, and
other investments by Foreign Subsidiaries in or with foreign obligors that, in the reasonable judgment of the Issuer, are of a credit quality comparable to those listed in clauses (1) through (6) above. 

“Change of Control” means the occurrence of any of the following events: 

(1) any “person” or “group” (as such terms are used in Sections 13(d) and 14(d) of the Exchange Act), is or becomes the
“beneficial owner” (as defined in Rules 13d-3 and 13d-5 under the Exchange Act (except that for purposes of this clause that person or group shall be deemed to have “beneficial ownership” of all securities that any such person or
group has the right to acquire, whether such right is exercisable immediately or only after the passage of time)), directly or indirectly, of Voting Stock representing more than 50% of the voting power of the total outstanding Voting Stock of the
Issuer; 
 (2) consummation of (a) any share exchange, consolidation or merger of the Issuer or series of such related transactions
(excluding a merger with a Wholly-Owned Restricted Subsidiary solely for the purpose of changing the Issuer’s name or jurisdiction of incorporation) or (b) any sale, lease or other transfer, in one transaction or a series of related
transactions, of all or substantially all of the consolidated assets of the Issuer and its Restricted Subsidiaries, taken as a whole, to any “person” or “group” within the meaning thereof in Section 13(d) of the Exchange
Act, other than one or more of the Wholly-Owned Restricted Subsidiaries; provided, however, that a transaction described in foregoing clause (a) or (b) where the holders of Voting

  
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Stock representing more than 50% of the voting power of the total outstanding Voting Stock of the Issuer immediately prior to such transaction own, directly or indirectly, Voting Stock
representing more than 50% of the voting power of the total outstanding Voting Stock of the continuing, surviving or resulting entity or the transferee immediately after such event shall not be a Change of Control; or 

(3) the Issuer shall adopt a Plan of Liquidation or dissolution or any such plan shall be approved by the stockholders of the Issuer. 

“Consolidated Amortization Expense” for any period means the amortization expense of the Issuer and the Restricted
Subsidiaries for such period, determined on a consolidated basis in accordance with GAAP. 
 “Consolidated Cash Flow” for
any period means, without duplication, the sum of the amounts for such period of: 
 (1) Consolidated Net Income; plus 

(2) in each case only to the extent (and in the same proportion) deducted in determining Consolidated Net Income and with respect to the
portion of Consolidated Net Income attributable to any Restricted Subsidiary only if a corresponding amount would be permitted at the date of determination to be distributed to the Issuer by such Restricted Subsidiary without prior approval (that
has not been obtained), pursuant to the terms of its charter and all agreements, instruments, judgments, decrees, orders, statutes, rules and governmental regulations applicable to such Restricted Subsidiary or its stockholders, 

(a) Consolidated Income Tax Expense, 

(b) Consolidated Amortization Expense (but only to the extent not included in Consolidated Interest Expense), 

(c) Consolidated Depreciation Expense, 

(d) Consolidated Interest Expense, and 

(e) all other non-cash items reducing Consolidated Net Income for such period, including any stock-based compensation expense, in each case
determined on a consolidated basis in accordance with GAAP; minus 
 (3) the aggregate amount of all non-cash items, determined on a
consolidated basis, to the extent such items increased Consolidated Net Income (including the reversal of accruals or reserves for charges that increased Consolidated Net Income at any time during the Four-Quarter Period ending on the Issue Date or
thereafter) for such period; minus 
 (4) cash disbursements in respect of previously accrued or reserved items increasing
Consolidated Cash Flow in that or prior periods. 

  
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 “Consolidated Depreciation Expense” for any period means the depreciation
expense of the Issuer and the Restricted Subsidiaries for such period, determined on a consolidated basis in accordance with GAAP. 

“Consolidated Income Tax Expense” for any period means the provision for taxes of the Issuer and the Restricted Subsidiaries,
determined on a consolidated basis in accordance with GAAP. 
 “Consolidated Interest Coverage Ratio” means the ratio of
(x) Consolidated Cash Flow during the Four-Quarter Period ending on or prior to the date of the transaction giving rise to the need to calculate the Consolidated Interest Coverage Ratio (the “Transaction Date”) to
(y) Consolidated Interest Expense for such Four-Quarter Period. For purposes of this definition, Consolidated Cash Flow and Consolidated Interest Expense shall be calculated after giving effect on a pro forma basis for the period of such
calculation to: 
 (1) the incurrence of any Indebtedness or the issuance of any Preferred Stock of any Restricted Subsidiary (and the
application of the proceeds thereof) and any repayment of other Indebtedness or the redemption of any Preferred Stock of any Restricted Subsidiary (and the application of the proceeds thereof), other than the incurrence or repayment of Indebtedness
in the ordinary course of business for working capital purposes pursuant to any revolving credit arrangement, occurring during the Four-Quarter Period or at any time subsequent to the last day of the Four-Quarter Period and on or prior to the
Transaction Date, as if such incurrence, issuance, repayment or redemption, as the case may be (and the application of the proceeds thereof), occurred on the first (1st) day of the
Four-Quarter Period; and 
 (2) any Asset Sale or Asset Acquisition (including any Asset Acquisition giving rise to the need to make such
calculation as a result of the Issuer or any Restricted Subsidiary (including any Person who becomes a Restricted Subsidiary as a result of such Asset Acquisition) incurring Acquired Indebtedness and also including any Consolidated Cash Flow
(including any pro forma expense and cost reductions calculated on a basis consistent with Regulation S-X under the Exchange Act) associated with any such Asset Acquisition) occurring during the Four-Quarter Period or at any time subsequent
to the last day of the Four-Quarter Period and on or prior to the Transaction Date, as if such Asset Sale or Asset Acquisition (including the incurrence of, or assumption or liability for, any such Acquired Indebtedness) occurred on the first (1st) day of the Four-Quarter Period. 
 If the Issuer or any Restricted Subsidiary directly or
indirectly guarantees Indebtedness of a third Person, the preceding sentence shall give effect to the incurrence of such guaranteed Indebtedness as if the Issuer or such Restricted Subsidiary had directly incurred or otherwise assumed such
guaranteed Indebtedness. 
 In calculating Consolidated Interest Expense for purposes of determining the denominator (but not the numerator) of this
Consolidated Interest Coverage Ratio: 
 (1) interest on outstanding Indebtedness determined on a fluctuating basis as of the Transaction
Date and which will continue to be so determined thereafter shall be deemed to have accrued at a fixed rate per annum equal to the rate of interest on such Indebtedness in effect on the Transaction Date; 

  
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 (2) if interest on any Indebtedness actually incurred on the Transaction Date may optionally be
determined at an interest rate based upon a factor of a prime or similar rate, a eurocurrency interbank offered rate, or other rates, then the interest rate in effect on the Transaction Date will be deemed to have been in effect during the
Four-Quarter Period; and 
 (3) notwithstanding clause (1) or (2) above, interest on Indebtedness determined on a fluctuating
basis, to the extent such interest is covered by agreements relating to Hedging Obligations, shall be deemed to accrue at the rate per annum resulting after giving effect to the operation of such agreements. 

“Consolidated Interest Expense” for any period means the sum, without duplication, of the total interest expense of the
Issuer and the Restricted Subsidiaries for such period, determined on a consolidated basis in accordance with GAAP and including without duplication: 

(1) imputed interest on Capitalized Lease Obligations and Attributable Indebtedness; 

(2) commissions, discounts and other fees and charges owed with respect to letters of credit securing financial obligations, bankers’
acceptance financing and receivables financings; 
 (3) the net costs associated with Hedging Obligations; 

(4) amortization of debt issuance costs, debt discount or premium and other financing fees and expenses (other than the write-off of deferred
debt issuance costs resulting from the initial offering of the Notes); 
 (5) the interest portion of any deferred payment obligations; 

(6) all other non-cash interest expense; 

(7) capitalized interest; 
 (8)
the product of (x) all dividend payments on any series of Disqualified Equity Interests of the Issuer or any Preferred Stock of any Restricted Subsidiary (other than any such Disqualified Equity Interests or any Preferred Stock held by the
Issuer or a Wholly-Owned Restricted Subsidiary or to the extent paid in Qualified Equity Interests), multiplied by (y) a fraction, the numerator of which is one and the denominator of which is one
minus the then current combined federal, state and local statutory tax rate of the Issuer and the Restricted Subsidiaries, expressed as a decimal; 

(9) all interest payable with respect to discontinued operations; and 

(10) all interest on any Indebtedness of any other Person guaranteed by the Issuer or any Restricted Subsidiary. 

  
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 Consolidated Interest Expense shall be calculated after giving effect to Hedging Obligations
(including associated costs) described in clause (1) of the definition of “Hedging Obligations,” but excluding unrealized gains and losses with respect to Hedging Obligations. 

“Consolidated Net Income” for any period means the net income (or loss) of the Issuer and the Restricted Subsidiaries for
such period determined on a consolidated basis in accordance with GAAP; provided, however, that there shall be excluded from such net income (to the extent otherwise included therein), without duplication: 

(1) the net income (or loss) of any Person (other than a Restricted Subsidiary) in which any Person other than the Issuer and the Restricted
Subsidiaries has an ownership interest, except to the extent that cash in an amount equal to any such income has actually been received by the Issuer or any of its Wholly-Owned Restricted Subsidiaries during such period; 

(2) except to the extent includible in the consolidated net income of the Issuer pursuant to the foregoing clause (1), the net income (or
loss) of any Person that accrued prior to the date that (i) such Person becomes a Restricted Subsidiary or is merged into or consolidated with the Issuer or any Restricted Subsidiary or (ii) the assets of such Person are acquired by the
Issuer or any Restricted Subsidiary; 
 (3) the net income of any Restricted Subsidiary during such period to the extent that the
declaration or payment of dividends or similar distributions by such Restricted Subsidiary of that income is not permitted by operation of the terms of its charter or any agreement, instrument, judgment, decree, order, statute, rule or governmental
regulation applicable to that Subsidiary during such period, except that the Issuer’s equity in a net loss of any such Restricted Subsidiary for such period shall be included in determining Consolidated Net Income; 

(4) for the purposes of calculating the Restricted Payments Basket only, in the case of a successor to the Issuer by consolidation, merger or
transfer of its assets, any income (or loss) of the successor prior to such merger, consolidation or transfer of assets; 
 (5) other than
for purposes of calculating the Restricted Payments Basket, any gain (or loss), together with any related provisions for taxes on any such gain (or the tax effect of any such loss), realized during such period by the Issuer or any Restricted
Subsidiary upon (i) the acquisition of any securities, or the extinguishment of any Indebtedness, of the Issuer or any Restricted Subsidiary or (ii) any Asset Sale by the Issuer or any Restricted Subsidiary; 

(6) any gains and losses due solely to fluctuations in currency values and the related tax effects according to GAAP; 

(7) any unrealized gains and losses with respect to Hedging Obligations; 

(8) any extraordinary, unusual or nonrecurring gain, charges and losses (including all restructuring costs, facilities relocation costs,
acquisition integration costs and fees, including cash severance payments made in connection with acquisitions, and any expense or charge related to the repurchase of Equity Interests or warrants or options to purchase Equity Interests), and the
related tax effects according to GAAP; 

  
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 (9) any acquisition-related expenses expensed in accordance with Statement of Financial
Accounting Standards No. 141(R) promulgated by the Financial Accounting Standards Board (“SFAS 141(R)”) and any gains or losses on any earn-out payments, contingent consideration or deferred purchase price in conjunction with
any Asset Acquisition determined in accordance with SFAS 141(R); 
 (10) any impairment charge or asset write-off, in each case pursuant to
GAAP, and the amortization of intangibles arising pursuant to GAAP; 
 (11) any non-cash compensation charges and deferred compensation
charges, including any arising from existing stock options resulting from any merger or recapitalization transaction; provided, however, that Consolidated Net Income for any period shall be reduced by any cash payments made during such
period by the Issuer or any Restricted Subsidiary in connection with any such deferred compensation, whether or not such reduction is in accordance with GAAP; and 

(12) inventory purchase accounting adjustments and amortization and impairment charges resulting from other purchase accounting adjustments in
connection with acquisition transactions. 
 In addition, any return of capital with respect to an Investment that increased the Restricted
Payments Basket pursuant to Section 4.08(a)(3)(v) or decreased the amount of Investments outstanding pursuant to clause (14) of the definition of “Permitted Investments” shall be excluded from Consolidated Net Income for purposes
of calculating the Restricted Payments Basket. 
 “Consolidated Secured Debt” means all Secured Indebtedness, without
duplication, that is Indebtedness of a type described in clause (1), (2), (3), (4)(i), (5), (6), (7), (8) or (9) of the definition thereof, in each case of the Issuer and its Restricted Subsidiaries determined on a consolidated basis in
accordance with GAAP and treating (i) any commitment to provide any Indebtedness under a revolving credit facility as though such commitment were fully drawn and (ii) all Permitted Indebtedness incurred or to be incurred under clause
(1) of the definition thereof as Secured Indebtedness regardless of whether such Indebtedness is secured by a Lien or not. 

“Consolidated Secured Leverage Ratio” means the ratio of (x) Consolidated Secured Debt as of the date of the transaction
giving rise to the need to calculate the Consolidated Secured Leverage Ratio (the “Secured Transaction Date”) to (y) Consolidated Cash Flow for the Four-Quarter Period ending on or prior to the Secured Transaction Date;
provided, however that “Consolidated Cash Flow” shall be calculated in the manner contemplated by, and subject to the adjustments provided in, the definition of the term “Consolidated Interest Coverage Ratio.” 

“Consolidated Total Assets” means, at any time of determination, the consolidated total assets of the Issuer and the
Restricted Subsidiaries determined on a consolidated basis in accordance with GAAP as of the most recent date for which financial statements of the Issuer are then available. 

  
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 “Corporate Trust Office” means the corporate trust office of the Trustee located
at 100 Wall Street, 16th Floor, New York, New York 10005, or such other office, designated by the Trustee by written notice to the Issuer, at which at any particular time its corporate trust business shall be administered. 

“Credit Agreement” means that certain new Credit Agreement, dated as of June 18, 2015, among, inter alios, the
Issuer, the lenders party thereto, the letter of credit issuers party thereto, Goldman Sachs Bank USA, as the B Term Loan Administrative Agent, General Electric Capital Corporation, as the Pro Rata Administrative Agent and the Collateral Agent,
General Electric Capital Corporation, as Syndication Agent, and Citizens Bank, N.A. and DNB Bank ASA, New York Branch, as Co-Documentation Agents, including any notes, guarantees, collateral and security documents, instruments and agreements
executed in connection therewith (including Hedging Obligations related to the Indebtedness incurred thereunder), and in each case as amended, restated, supplemented or otherwise modified from time to time before, on or after the Issue Date,
including one or more agreements extending the maturity of, refinancing, refunding, replacing or otherwise restructuring (including increasing the amount of borrowings or other Indebtedness outstanding or available to be borrowed thereunder) all or
any portion of the Indebtedness under such agreement or agreements, and any successor or replacement agreement or agreements with the same or any other agent or agents, creditor, lender or group of creditors or lenders. 

“Credit Facilities” means, with respect to the Issuer or any Subsidiary, one or more debt facilities (including any Credit
Agreement) or commercial paper facilities with banks or institutional or other similar lenders providing for revolving credit loans, term loans, receivables financing (including through the sale of receivables to such lenders or to special purpose
entities formed to borrow from such lenders against such receivables), letters of credit or other similar debt financing arrangements, in each case, as amended, restated, supplemented, modified, extended, renewed, refunded, replaced, refinanced or
otherwise restructured (including any increase in the amount of borrowings or other Indebtedness outstanding or available to be borrowed thereunder) in whole or in part from time to time. 

“Custodian” means any receiver, trustee, assignee, liquidator or similar official under any Bankruptcy Law. 

“Default” means (1) any Event of Default or (2) any event, act or condition that, after notice or the passage of
time or both, would be an Event of Default. 
 “Depository” means The Depository Trust Company, New York, New York, or a
successor thereto that is a clearing agency registered under the Exchange Act or other applicable statute or regulation. 

“Designated Senior Debt” means (1) Senior Debt under or in respect of any Credit Facility (including any Credit
Agreement), and (2) any other Indebtedness constituting Senior Debt which, in the case of clause (2), at the time of determination, (x) has an aggregate principal amount of at least $25.0 million and (y) is specifically designated in
the instrument evidencing such Senior Debt as “Designated Senior Debt” for purposes of this Indenture. 

  
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 “Disqualified Equity Interests” of any Person means any class of Equity
Interests of such Person that, by its terms, or by the terms of any related agreement or of any security into which it is convertible, puttable or exchangeable, is, or upon the happening of any event or the passage of time would be, required to be
redeemed by such Person, whether or not at the option of the holder thereof (but excluding redemption at the option of such Person), or matures or is mandatorily redeemable, pursuant to a sinking fund obligation or otherwise, in whole or in part, on
or prior to the date which is ninety-one (91) days after the Maturity Date; provided, however, that any class of Equity Interests of such Person that, by its terms, authorizes such Person to satisfy in full its obligations with
respect to the payment of dividends or upon maturity, redemption (pursuant to a sinking fund or otherwise) or repurchase thereof or otherwise by the delivery of Equity Interests that are not Disqualified Equity Interests (other than the payment of
cash in lieu of delivery of fractional shares of Equity Interests), and that is not convertible, puttable or exchangeable for Disqualified Equity Interests or Indebtedness, will not be deemed to be Disqualified Equity Interests so long as such
Person satisfies its obligations with respect thereto solely by the delivery of Equity Interests that are not Disqualified Equity Interests (other than the payment of cash in lieu of delivery of fractional shares of Equity Interests); provided
further, however, that any Equity Interests that would not constitute Disqualified Equity Interests but for provisions thereof giving holders thereof (or the holders of any security into or for which such Equity Interests is convertible,
exchangeable or exercisable) the right to require the Issuer to redeem such Equity Interests upon the occurrence of a change of control or an asset disposition occurring prior to the Maturity Date shall not constitute Disqualified Equity Interests
if the change in control or asset disposition provisions applicable to such Equity Interests are no more favorable to such holders than the provisions set forth in Section 4.06 and Section 4.10, respectively, and such Equity Interests
specifically provide that the Issuer will not redeem any such Equity Interests pursuant to such provisions prior to the Issuer’s purchase of the Notes as required pursuant to the provisions set forth in Section 4.06 and Section 4.10,
respectively; provided further, however, in no event shall the Series B Preferred Stock on the terms thereof existing on the Issue Date (or any other Preferred Stock issued by the Issuer on substantially similar terms with regard to
the foregoing matters in this definition) be deemed to be Disqualified Equity Interests. 
 “Dollars” and
“$” mean the currency of the United States of America. 
 “Domestic Subsidiary” means any Subsidiary of
the Issuer that is not a Foreign Subsidiary. 
 “Equity Interests” of any Person means (1) any and all shares or other
equity interests (including common stock, preferred stock, limited liability company interests and partnership interests) in such Person and (2) all rights to purchase, warrants or options (whether or not currently exercisable), participations
or other equivalents of or interests in (however designated) such shares or other interests in such Person; provided, however, that no Indebtedness under the 2007 Convertible Notes or any other Indebtedness of the Issuer or any
Subsidiary of the Issuer that is convertible into Equity Interests of such Person shall be deemed to be Equity Interests of such Person prior to conversion thereof into such Equity Interests. 

“Exchange Act” means the U.S. Securities Exchange Act of 1934, as amended. 

  
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 “Existing Senior Subordinated Notes” means, collectively, the 2010 Senior
Subordinated Notes and the 2013 Senior Subordinated Notes. 
 “Existing Senior Subordinated Notes Indentures” means,
collectively, the 2010 Senior Subordinated Notes Indenture and the 2013 Senior Subordinated Notes Indenture. 
 “Fair Market
Value” means, with respect to any asset, the price (after taking into account any liabilities relating to such assets) that would be negotiated in an arm’s-length transaction for cash between a willing seller and a willing and able
buyer, neither of which is under any compulsion to complete the transaction, as such price is determined in good faith by the Board of Directors of the Issuer or a duly authorized committee thereof, as evidenced by a resolution of such Board of
Directors or committee. 
 “Foreign Subsidiary” means, with respect to any Person, any Subsidiary of such Person that is
not organized or existing under the laws of the United States, any state thereof, the District of Columbia, or any territory thereof and any Subsidiary of such Foreign Subsidiary (whether or not such Subsidiary of such Foreign Subsidiary is
organized or existing under the laws of the United States, any state thereof, the District of Columbia, or any territory thereof). 

“Four-Quarter Period” means the most recent four consecutive full fiscal quarters of the Issuer for which financial
statements are available. 
 “GAAP” means generally accepted accounting principles set forth in the opinions and
pronouncements of the Accounting Principles Board of the American Institute of Certified Public Accountants and statements and pronouncements of the Financial Accounting Standards Board or in such other statements by such other entity as may be
approved by a significant segment of the accounting profession of the United States, as in effect on May 12, 2009. 

“guarantee” means a direct or indirect guarantee by any Person of any Indebtedness of any other Person and includes any
obligation, direct or indirect, contingent or otherwise, of such Person: (1) to purchase or pay (or advance or supply funds for the purchase or payment of) Indebtedness of such other Person (whether arising by virtue of partnership
arrangements, or by agreements to keep-well, to purchase assets, goods, securities or services (unless such purchase arrangements are on arm’s-length terms and are entered into in the ordinary course of business), to take-or-pay, or to maintain
financial statement conditions or otherwise); or (2) entered into for purposes of assuring in any other manner the obligee of such Indebtedness of the payment thereof or to protect such obligee against loss in respect thereof (in whole or in
part), and “guarantee,” when used as a verb, and “guaranteed” have correlative meanings. 

“Guarantee” means the senior subordinated guarantee by each of the Guarantors of the Issuer’s obligations under this
Indenture and the Notes as provided in Article Eleven. 
 “Guarantor Senior Debt” means, with respect to any Guarantor, the
principal of, premium, if any, and interest (including any interest accruing subsequent to the filing of a petition of bankruptcy at the rate provided for in the documentation with respect thereto, whether or not such interest is an allowed claim
under applicable law) on any Indebtedness of such Guarantor, whether outstanding on the Issue Date or thereafter created, incurred or assumed, unless, in the case of any particular Indebtedness, the instrument creating or evidencing the same or
pursuant to which the same is outstanding expressly provides that such Indebtedness shall not be senior in right of payment to the Guarantees and the Notes. 

  
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 Without limiting the generality of the foregoing, “Guarantor Senior Debt” shall also
include the principal of, premium, if any, and interest (including any interest accruing subsequent to the filing of a petition of bankruptcy at the rate provided for in the documentation with respect thereto, whether or not such interest is an
allowed claim under applicable law) on, and all other amounts owing in respect of: 
 (1) all obligations of every nature of such Guarantor
under, or with respect to, any Credit Facility (including any Credit Agreement), including obligations to pay principal and interest, reimbursement obligations under letters of credit, fees, expenses and indemnities (and guarantees thereof), and
including all obligations of each Guarantor under guarantees under or with respect to any of the foregoing or otherwise under or with respect to any Credit Facility (including any Credit Agreement); 

(2) all obligations of every nature of such Guarantor under or with respect to any Hedging Obligations in respect of any Credit Facility
(including any Credit Agreement) (and guarantees thereof); and 
 (3) all obligations of every nature of such Guarantor under, or with
respect to, its guarantee of the Issuer’s obligations under, or with respect to, the Senior Notes; 
 in each case whether outstanding on the Issue
Date or thereafter incurred. 
 Notwithstanding the foregoing, “Guarantor Senior Debt” shall not include: 

(1) any Indebtedness of such Guarantor to the Issuer or any of its Subsidiaries; 

(2) Indebtedness to, or guaranteed on behalf of, any director, officer or employee of the Issuer or any of its Subsidiaries (including amounts
owed for compensation); 
 (3) obligations to trade creditors and other amounts incurred (but not under any Credit Facility (including any
Credit Agreement)) in connection with obtaining goods, materials or services; 
 (4) Indebtedness represented by Disqualified Equity
Interests; 
 (5) any liability for taxes owed or owing by such Guarantor; 

(6) that portion of any Indebtedness incurred in violation of this Indenture (but, as to any such obligation, no such violation shall be
deemed to exist for purposes of this clause (6) if the holder(s) of such obligation or their representative shall have received an Officers’ Certificate (or representation or warranty) of such Guarantor (any such Officers’
Certificate, notwithstanding the definition of such term, to be executed by analogous officers of the Guarantor rather than the Issuer) to the effect that the incurrence of such Indebtedness does not (or, in the case of revolving credit
indebtedness, the incurrence of the entire committed amount thereof at the date on which the initial borrowing thereunder is made would not) violate the provisions of this Indenture); 

  
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 (7) Indebtedness which, when incurred and without respect to any election under
Section 1111(b) of Title 11, United States Code, is without recourse to such Guarantor; 
 (8) Indebtedness under or evidenced by such
Guarantor’s guarantee of the Issuer’s obligations under, or with respect to, the Existing Senior Subordinated Notes, and any Indebtedness that expressly provides that it ranks pari passu in right of payment with any such guarantee
Indebtedness; and 
 (9) any Indebtedness (including any Pari Passu Indebtedness or Subordinated Indebtedness) which is, by its express
terms, subordinated in right of payment to any other Indebtedness of such Guarantor. 
 “Guarantors” means (1) each
party named as such on the signature page of this Indenture, which (subject to the proviso below), collectively, consist of each Domestic Subsidiary on the Issue Date that guarantees any Indebtedness or other Obligation under any Credit Agreement,
and (2) each other Person that is required to, or at the election of the Issuer does, become a Guarantor by the terms of this Indenture after the Issue Date, in each case, until such Person is released from its Guarantee in accordance with the
terms of this Indenture; provided, however, in each case, that in no event shall SPDH, Inc. be a Guarantor unless the Issuer so elects by notice to the Trustee delivered in accordance with this Indenture (in which case such Subsidiary
shall become a Guarantor as provided in Section 4.13). 
 “Hedging Obligations” of any Person means the obligations of
such Person pursuant to (1) any interest rate swap agreement, interest rate collar agreement or other similar agreement or arrangement designed to alter the risks to that Person arising from fluctuations in interest rates, (2) agreements
or arrangements designed to alter the risks to that Person arising from fluctuations in foreign currency exchange rates in the conduct of its operations, or (3) any forward contract, commodity swap agreement, commodity option agreement or other
similar agreement or arrangement designed to protect such Person against fluctuations in commodity prices, in each case entered into in the ordinary course of business for bona fide hedging purposes and not for the purpose of speculation.

 “Holder” means any registered holder, from time to time, of the Notes. 

“incur” means, with respect to any Indebtedness or Obligation, incur, create, issue, assume, guarantee or otherwise become
directly or indirectly liable, contingently or otherwise, with respect to such Indebtedness or Obligation; provided, however, that (1) the Indebtedness of a Person existing at the time such Person became a Restricted Subsidiary shall be
deemed to have been incurred by such Restricted Subsidiary at such time and (2) neither the accrual of interest nor the accretion of original issue discount shall be deemed to be an incurrence of Indebtedness. 

  
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 “Indebtedness” of any Person at any date means, without duplication: 

(1) all liabilities, contingent or otherwise, of such Person for borrowed money (whether or not the recourse of the lender is to the whole of
the assets of such Person or only to a portion thereof); 
 (2) all obligations of such Person evidenced by bonds, debentures, notes or
other similar instruments; 
 (3) all reimbursement obligations of such Person in respect of letters of credit, letters of guaranty,
bankers’ acceptances and similar credit transactions; 
 (4) (i) all obligations of such Person to pay the deferred and unpaid purchase
price of property or services, and (ii) all obligations of such Person under conditional sale or other title retention agreements relating to the assets purchased by such Person; provided, however, that in no event shall the
following constitute “Indebtedness” under this Indenture: (x) trade payables and other accrued liabilities incurred by such Person in the ordinary course of business and (y) customary adjustments of purchase price, contingent
payments, earnout payments or similar obligations of such Person arising under any of the documents pertaining to any acquisition of any Person or assets or Equity Interests of any Person or any sale, transfer or other disposition of assets to any
Person, in each case in this clause (y) to the extent not yet determined, due and payable; 
 (5) the maximum fixed involuntary
redemption or repurchase price of all Disqualified Equity Interests of such Person; 
 (6) all Capitalized Lease Obligations of such Person;

 (7) all Indebtedness of others secured by a Lien on any asset of such Person, whether or not such Indebtedness is assumed by such Person;

 (8) all Indebtedness of others guaranteed by such Person to the extent of such guarantee; provided, however, that
Indebtedness of the Issuer or its Subsidiaries that is guaranteed by the Issuer or the Issuer’s Subsidiaries shall only be counted once in the calculation of the amount of Indebtedness of the Issuer and its Subsidiaries on a consolidated basis;

 (9) all Attributable Indebtedness; and 

(10) to the extent not otherwise included in this definition, Hedging Obligations of such Person, determined as the net amount of all payments
that would be required to be made in respect thereof in the event of a termination (including an early termination) on the date of determination. 

The amount of any Indebtedness which is incurred at a discount to the principal amount at maturity thereof as of any date shall be deemed to
have been incurred at the accreted value thereof as of such date. The amount of Indebtedness of any Person at any date shall be the outstanding balance at such date of all unconditional obligations as described above, the maximum liability of such
Person for any such contingent obligations at such date and, in the 

  
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 case of clause (7), the lesser of (a) the Fair Market Value of any asset subject to a Lien securing the
Indebtedness of others on the date that the Lien attaches and (b) the amount of the Indebtedness secured. For purposes of clause (5), the “maximum fixed involuntary redemption or repurchase price” of any Disqualified Equity Interests
that do not have a fixed involuntary redemption or repurchase price shall be calculated in accordance with the terms of such Disqualified Equity Interests as if such Disqualified Equity Interests were redeemed or repurchased on any date on which an
amount of Indebtedness outstanding shall be required to be determined pursuant to this Indenture. 
 “Independent Director”
means a director of the Issuer who: 
 (1) is independent with respect to the transaction at issue; 

(2) does not have any material financial interest in the Issuer or any of its Affiliates (other than as a result of holding securities of the
Issuer); and 
 (3) has not and whose Affiliates or affiliated firm has not, at any time during the twelve months prior to the taking of any
action hereunder, directly or indirectly, received, or entered into any understanding or agreement to receive, any compensation, payment or other benefit, of any type or form, from the Issuer or any of its Affiliates, other than customary
directors’ fees for serving on the Board of Directors of the Issuer or any Affiliate and reimbursement of out-of-pocket expenses for attendance at the Issuer’s or Affiliate’s board and board committee meetings. 

“Independent Financial Advisor” means an accounting, appraisal or investment banking firm of recognized standing that is, in
the reasonable judgment of the Issuer’s Board of Directors, qualified to perform the task for which it has been engaged and disinterested and independent with respect to the Issuer and its Affiliates. 

“Institutional Accredited Investor” or “IAI” means an “accredited investor” within the meaning of
Rule 501(a)(1), (2), (3) or (7) under the Securities Act. 
 “interest” means, with respect to the Notes,
interest on the Notes. 
 “Interest Payment Date” means the Stated Maturity of an installment of interest on the Notes.

 “Investments” of any Person means: 

(1) all direct or indirect investments by such Person in any other Person in the form of loans, advances or capital contributions or other
credit extensions constituting Indebtedness of such other Person, and any guarantee of Indebtedness of any other Person; 
 (2) all
purchases (or other acquisitions for consideration) by such Person of Indebtedness, Equity Interests or other securities of any other Person (other than any such purchase that constitutes a Restricted Payment of the type described in clause
(2) of the definition thereof); 

  
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 (3) all other items that would be classified as investments (including purchases of assets
outside the ordinary course of business) on a balance sheet of such Person prepared in accordance with GAAP; and 
 (4) the Designation after
the Issue Date of any Subsidiary as an Unrestricted Subsidiary. 
 Except as otherwise expressly specified in this definition, the amount of any Investment
(other than an Investment made in cash) shall be the Fair Market Value thereof on the date such Investment is made. The amount of any Investment pursuant to clause (4) shall be the Designation Amount determined in accordance with
Section 4.16. Notwithstanding the foregoing, neither (a) purchases or redemptions of Equity Interests of the Issuer nor (b) acquisitions of assets by any Person shall be deemed to be Investments. 

“Issue Date” means the date on which the Initial Notes are originally issued. 

“Issuer” means the party named as such above until a successor replaces it and thereafter means the successor. 

“Lien” means, with respect to any asset, any mortgage, deed of trust, lien (statutory or other), pledge, lease, easement,
restriction, charge, security interest or other similar encumbrance of any kind or nature in respect of such asset, whether or not filed, recorded or otherwise perfected under applicable law, including any conditional sale or other title retention
agreement, and any lease in the nature thereof. 
 “Major Foreign Exchange” means an exchange which is the primary non-U.S.
trading location for one or more stocks included in the Morgan Stanley Capital International Europe, Australasia and Far East Index (or if such index does not exist a comparable then existing index). 

“Maturity Date” means July 1, 2023. 

“Moody’s” means Moody’s Investors Service, Inc., and its successors. 

“Net Available Proceeds” means, with respect to any Asset Sale, the proceeds thereof in the form of cash or Cash Equivalents,
net of: 
 (1) brokerage commissions and other fees and expenses (including fees and expenses of legal counsel, accountants and investment
banks) incurred in connection with such Asset Sale; 
 (2) provisions for taxes payable as a result of such Asset Sale (after taking into
account any available tax credits or deductions and any tax sharing arrangements); 
 (3) amounts required to be paid to any Person (other
than the Issuer or any Restricted Subsidiary) owning a beneficial interest in the assets subject to the Asset Sale or having a Lien thereon; 

  
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 (4) payments of unassumed liabilities (not constituting Indebtedness) relating to the assets sold
at the time of, or within one hundred eighty (180) days after the date of, such Asset Sale; and 
 (5) appropriate amounts to be
provided by the Issuer or any Restricted Subsidiary, as the case may be, as a reserve required in accordance with GAAP against any adjustment in the sale price of such asset or assets or liabilities associated with such Asset Sale and retained by
the Issuer or any Restricted Subsidiary, as the case may be, after such Asset Sale, including pensions and other post-employment benefit liabilities, liabilities related to environmental matters and liabilities under any indemnification obligations
associated with such Asset Sale, all as reflected in an Officers’ Certificate delivered to the Trustee; provided, however, that any amounts remaining after adjustments, revaluations or liquidations of such reserves shall
constitute Net Available Proceeds. 
 “Non-Recourse Debt” means Indebtedness of an Unrestricted Subsidiary: 

(1) as to which neither the Issuer nor any Restricted Subsidiary (i) provides credit support of any kind (including any undertaking,
agreement or instrument that would constitute Indebtedness), (ii) is directly or indirectly liable as a guarantor or otherwise, or (iii) constitutes the lender; provided, however, that (x) Indebtedness of an Unrestricted
Subsidiary as to which the Issuer or any Restricted Subsidiary provides any such credit support or is so liable as a guarantor or otherwise shall not constitute “Non-Recourse Debt” to the extent that
the aggregate obligations of such Unrestricted Subsidiary under any such support or guarantee arrangements, taken together with all such obligations of all other Unrestricted Subsidiaries, do not exceed $25.0 million in the aggregate, and
(y) an intercompany loan from the Issuer or any Restricted Subsidiary to an Unrestricted Subsidiary shall be deemed Non- Recourse Debt if such loan at the time such Subsidiary is designated an Unrestricted Subsidiary or if made later, at the
time such intercompany loan is made, was permitted under and made in compliance with Section 4.08; and 
 (2) no default with respect
to which (including any rights that the holders thereof may have to take enforcement action against an Unrestricted Subsidiary) would permit upon notice, lapse of time or both any holder or holders of any other Indebtedness (other than the Notes) of
the Issuer or any Restricted Subsidiary in an aggregate principal amount of $50.0 million or more to declare a default on the other Indebtedness or cause the payment thereof to be accelerated or payable prior to its stated maturity. 

“Non-U.S. Person” means a person other than a U.S. Person (as such term is defined in Regulation S). 

“Notes” means, collectively, the Issuer’s 6.375% Senior Subordinated Notes due 2023 issued in accordance with
Section 2.02 (whether issued on the Issue Date, issued as Additional Notes or otherwise issued after the Issue Date) treated as a single class of securities under this Indenture, as amended or supplemented from time to time in accordance with
the terms of this Indenture. 

  
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 “Obligation” means any principal, interest, penalties, fees, indemnification,
reimbursements, costs, expenses, damages and other liabilities payable under the documentation governing any Indebtedness. 

“Offering Memorandum” means the offering memorandum, dated June 11, 2015, under which the Initial Notes are being
offered. 
 “Officer” means any of the following of the Issuer: the Chairman of the Board of Directors, the Chief Executive
Officer, the President, any Vice President, the Chief Financial Officer, the Treasurer, any Assistant Treasurer, the Secretary or any Assistant Secretary. 

“Officers’ Certificate” means a certificate signed by two Officers. 

“Opinion of Counsel” means a written opinion from legal counsel who is reasonably acceptable to the Trustee. The counsel may
(but need not) be an employee of, or counsel to, the Issuer, a Guarantor or the Trustee. 
 “Pari Passu Indebtedness” means
any Indebtedness of the Issuer or any Guarantor that ranks pari passu in right of payment with the Notes or the Guarantees, as applicable, including (i) the Existing Senior Subordinated Notes and the Guarantors’ related guarantees
thereof and any Indebtedness of the Issuer or any Guarantor that expressly provides that it ranks pari passu in right of payment with any of the Existing Senior Subordinated Notes or such guarantees, as the case may be, and (ii) the 2007
Convertible Notes and any Indebtedness of the Issuer that expressly provides that it ranks pari passu in right of payment with the 2007 Convertible Notes. 

“Permitted Business” means the businesses engaged in by the Issuer and its Subsidiaries on the Issue Date as described in the
Offering Memorandum, businesses that are otherwise within the healthcare, life sciences or diagnostic industries and businesses that are reasonably similar, ancillary or related to, or that are a reasonable extension, development or expansion of,
any of the foregoing. 
 “Permitted Investments” means: 

(1) Investments by the Issuer or any Restricted Subsidiary (i) in any Restricted Subsidiary or (ii) including the purchase price
paid for and reasonable transaction costs related thereto, in any Person that is or will become immediately after or substantially concurrent with such Investment a Restricted Subsidiary or that will merge or consolidate into the Issuer or a
Restricted Subsidiary (including the exercise or performance of any rights or obligations to acquire any equity or ownership interest in any joint venture under the terms of the agreements governing such joint venture); 

(2) Investments in the Issuer by any Restricted Subsidiary; 

(3) loans and advances to directors, employees and officers of the Issuer and the Restricted Subsidiaries (i) for bona fide
business purposes and (ii) to purchase Equity Interests of the Issuer not in excess of $5.0 million at any one time outstanding, in each case, in addition to any such loans outstanding on the Issue Date; 

  
 -22- 

 (4) Hedging Obligations incurred pursuant to Section 4.07(b)(4); 

(5) cash and Cash Equivalents; 

(6) receivables owing to the Issuer or any Restricted Subsidiary and payable or dischargeable in accordance with customary trade terms;
provided, however, that such trade terms may include such concessionary trade terms as the Issuer or any such Restricted Subsidiary deems reasonable under the circumstances; 

(7) Investments in securities of trade creditors or customers received pursuant to any plan of reorganization or similar arrangement upon the
bankruptcy or insolvency of such trade creditors or customers; 
 (8) Investments made by the Issuer or any Restricted Subsidiary as a
result of the receipt of non-cash consideration from an Asset Sale that was made in compliance with Section 4.10; 
 (9) lease, utility
and other similar deposits in the ordinary course of business; 
 (10) Investments made by the Issuer or a Restricted Subsidiary for
consideration consisting only of Qualified Equity Interests of the Issuer; 
 (11) stock, obligations or securities received in settlement
of debts created in the ordinary course of business and owing to the Issuer or any Restricted Subsidiary or in satisfaction of judgments; 

(12) Investments existing on the Issue Date; 

(13) acquisitions (including the purchase price paid for and reasonable transaction costs related thereto) by the Issuer or any Restricted
Subsidiary of (i) Equity Interests of another Person engaged in the Permitted Business and who will thereafter become a Restricted Subsidiary (including the exercise or performance of any rights or obligations to acquire any equity or ownership
interest in any joint venture under the terms of the agreements governing such joint venture), (ii) all or a substantial portion of the assets of a Person engaged in or of a line of business, in each case, within the Permitted Business, or
(iii) any other assets within the Permitted Business; and 
 (14) other Investments having an aggregate Fair Market Value at any one
time outstanding not to exceed the greater of (x) $200.0 million and (y) 3.0% of Consolidated Total Assets (with the Fair Market Value of each Investment being determined as of the date made and without regard to subsequent changes in
value) (it being understood that any Investment permitted under this clause (14) shall remain so permitted notwithstanding any decrease in Consolidated Total Assets). (For avoidance of doubt, in determining the amount of any Investments made
and outstanding under this clause (14) in any joint venture in connection with any contribution, transfer or other disposition of assets by the Issuer or any of its Restricted Subsidiaries to such joint venture, the aggregate amount of cash and
Cash Equivalents received by the Issuer and its Restricted Subsidiaries in consideration for such contribution, transfer or disposition shall be netted against the Fair Market Value of the assets so contributed, transferred or disposed of.) 

  
 -23- 

 The amount of Investments outstanding at any time pursuant to clause (14) above shall be
deemed to be reduced: 
 (a) upon the disposition or repayment of or return on any Investment made pursuant to clause (14) above, by an
amount equal to the return of capital with respect to such Investment to the Issuer or any Restricted Subsidiary (to the extent not included in the computation of Consolidated Net Income), less the cost of the disposition of such Investment
and net of taxes; and 
 (b) upon a Redesignation of an Unrestricted Subsidiary as a Restricted Subsidiary, by an amount equal to the lesser
of (x) the Fair Market Value of the Issuer’s proportionate interest in such Subsidiary immediately following such Redesignation, and (y) the aggregate amount of Investments in such Subsidiary that increased (and did not previously
decrease) the amount of Investments outstanding pursuant to clause (14) above. 
 “Permitted Junior Securities” means:

 (1) Equity Interests in the Issuer or any Guarantor; and 

(2) debt securities, 
 in the case of each of
clauses (1) and (2), provided for by a plan of reorganization or readjustment and that are subordinated to (a) all Senior Debt and Guarantor Senior Debt and (b) any securities issued in exchange for Senior Debt, in each case, to
substantially the same extent as, or to a greater extent than, the Notes and the Guarantees are subordinated to Senior Debt and Guarantor Senior Debt under this Indenture. 

“Permitted Liens” means the following types of Liens: 

(1) Liens for taxes, assessments or governmental charges or claims either (i) not delinquent or payable without penalty or
(ii) contested in good faith by appropriate proceedings and as to which the Issuer or the Restricted Subsidiaries shall have set aside on its books such reserves as may be required pursuant to GAAP; 

(2) statutory, contractual or common law Liens of landlords and mortgagees of landlords and Liens of carriers, warehousemen, mechanics,
suppliers, materialmen, repairmen or workmen and other Liens imposed by law or arising in the ordinary course of business for sums not yet delinquent or being contested in good faith, if such reserve or other appropriate provision, if any, as shall
be required by GAAP shall have been made in respect thereof; 
 (3) Liens arising or pledges or deposits made in the ordinary course of
business in connection with workers’ compensation, unemployment insurance, social security or other types of government insurance benefits, or made in lieu of, or to secure the performance of tenders, statutory obligations, surety, customs,
reclamation, performance or appeal bonds, bids, leases, government, sales or other trade contracts, performance and return-of-money bonds and other similar obligations (exclusive of obligations for the payment of borrowed money); 

  
 -24- 

 (4) Liens upon specific items of inventory, equipment or other goods and proceeds of any Person
securing such Person’s obligations in respect of bankers’ acceptances issued or created for the account of such Person to facilitate the purchase, shipment or storage of such inventory or other goods; 

(5) attachment or judgment Liens not giving rise to a Default so long as any appropriate legal proceedings which may have been duly initiated
for the review of such judgment have not been finally terminated or the period within which the proceedings may be initiated has not expired, and pledges or cash deposits made in lieu of, or to secure the performance of, judgment or appeal bonds in
connection with the foregoing; 
 (6) easements, rights-of-way, zoning restrictions and other similar charges, restrictions, licenses,
reservations, covenants, encroachments or other similar encumbrances in respect of real property or immaterial imperfections of title which are customary or do not, in the aggregate, impair in any material respect the ordinary conduct of the
business of the Issuer and the Restricted Subsidiaries taken as a whole; 
 (7) (i) Liens securing reimbursement obligations with respect to
commercial letters of credit which encumber documents, goods covered thereby, and other assets relating to such letters of credit and products and proceeds thereof and (ii) Liens securing reimbursement obligations with respect to commercial
letters of credit, letters of credit issued to landlords and other letters of credit issued, in each case in the ordinary course of business in an aggregate face amount not exceeding $26.25 million at any time; 

(8) Liens encumbering deposits made to secure obligations arising from statutory, regulatory, contractual or warranty requirements of the
Issuer or any Restricted Subsidiary, including rights of offset and setoff; 
 (9) bankers’ Liens, rights of setoff and other similar
Liens existing solely with respect to cash and Cash Equivalents on deposit in one or more of accounts maintained by the Issuer or any Restricted Subsidiary, in each case granted in the ordinary course of business in favor of the bank or banks with
which such accounts are maintained, securing amounts owing to such bank with respect to cash management and operating account arrangements, including those involving pooled accounts and netting arrangements (including any Liens securing Permitted
Indebtedness incurred in reliance on Section 4.07(b)(8)); provided, however, that in no case shall any such Liens secure (either directly or indirectly) the repayment of any Indebtedness (except such Permitted Indebtedness
expressly referenced above); 
 (10) leases or subleases (or any Liens on the property related thereto) granted to others that do not
materially interfere with the ordinary course of business of the Issuer or any Restricted Subsidiary; 
 (11) licenses and sublicenses of
intellectual property granted to third parties in the ordinary course of business; 

  
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 (12) Liens arising from filing Uniform Commercial Code financing statements regarding leases or
other transactions that are not secured transactions; 
 (13) Liens securing all of the Notes and the Guarantees; 

(14) (i) Liens securing Senior Debt or Guarantor Senior Debt (including, in each case, Indebtedness under any Credit Facility (including any
Credit Agreement, including with respect to letters of credit or bankers’ acceptances issued thereunder)); and (ii) Liens securing Hedging Obligations permitted by Section 4.07(b)(4)(i) with respect to Indebtedness under any Credit
Facility (including any Credit Agreement), which Liens in this clause (ii) extend only to assets securing such Indebtedness under such Credit Facility or Credit Agreement; 

(15) Liens securing Indebtedness of any Domestic Subsidiary that is not a Guarantor (other than Indebtedness that is Subordinated Indebtedness
or that ranks pari passu in right of payment with the Notes or any Guarantee), provided that such Liens do not extend to the assets of a Person who is not liable for such Indebtedness, whether as a borrower, a guarantor or otherwise;

 (16) Liens securing Indebtedness of Foreign Subsidiaries that relate solely to the Equity Interests or assets of Foreign Subsidiaries;

 (17) Liens existing on the Issue Date securing Indebtedness outstanding on the Issue Date; 

(18) Liens in favor of the Issuer or a Restricted Subsidiary; 

(19) Liens securing Purchase Money Indebtedness; 

(20) Liens securing Acquired Indebtedness permitted to be incurred under this Indenture; provided, however, that the Liens do
not extend to assets not subject to such Lien at the time of acquisition (other than improvements thereon) and are no more favorable to the lienholders than those securing such Acquired Indebtedness prior to the incurrence of such Acquired
Indebtedness by the Issuer or a Restricted Subsidiary; 
 (21) Liens on assets of a Person existing at the time such Person is acquired or
merged with or into or consolidated with the Issuer or any such Restricted Subsidiary (and not created in anticipation or contemplation thereof); 

(22) Liens to secure Refinancing Indebtedness of Indebtedness secured by Liens referred to in the foregoing clauses (17), (20) and
(21) and this clause (22); provided, however, that in each case such Liens do not extend to any additional assets (other than improvements thereon and replacements thereof); 

(23) Liens to secure Attributable Indebtedness or that are incurred pursuant to a Sale and Leaseback Transaction that complies with
Section 4.18; provided, however, that any such Lien shall not extend to or cover any assets of the Issuer or any Restricted Subsidiary other than the assets which are the subject of the Sale and Leaseback Transaction in which the
Attributable Indebtedness is incurred; 

  
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 (24) Liens in favor of customs and revenue authorities arising as a matter of law to secure
payment of customs duties in connection with the importation of goods; 
 (25) Liens securing Permitted Indebtedness incurred in reliance on
Section 4.07(b)(16); provided, however, that this clause (25) shall not permit Liens on the assets of any Domestic Subsidiary to secure Indebtedness of any Foreign Subsidiary; and 

(26) Liens incurred in the ordinary course of business of the Issuer or any Restricted Subsidiary with respect to obligations (other than
Indebtedness) that do not in the aggregate exceed $35.0 million at any one time outstanding. 
 “Person” means any
individual, corporation, partnership, limited liability company, joint venture, incorporated or unincorporated association, joint-stock company, trust, unincorporated organization or government or other agency or political subdivision thereof or
other entity of any kind. 
 “P&G JV Agreements” means the various joint venture, limited liability company, asset
transfer and contribution agreements dated on or about May 17, 2007 among the Issuer and certain of its Subsidiaries and Procter & Gamble RHD, Inc., Procter & Gamble International Operations, SA and certain of their
Affiliates, and the other agreements, instruments and documents executed or delivered in connection therewith on or after such date. 

“P&G JV Companies” means US CD LLC, a Delaware limited liability company, and SPD Swiss Precision Diagnostics GmbH, a
company organized under the laws of Switzerland, and any subsidiaries of either of them. 
 “Plan of Liquidation” with
respect to any Person, means a plan that provides for, contemplates or the effectuation of which is preceded or accompanied by (whether or not substantially contemporaneously, in phases or otherwise): (1) the sale, lease, conveyance or other
disposition of all or substantially all of the assets of such Person otherwise than as an entirety or substantially as an entirety; and (2) the distribution of all or substantially all of the proceeds of such sale, lease, conveyance or other
disposition of all or substantially all of the remaining assets of such Person to holders of Equity Interests of such Person. 

“Preferred Stock” means, with respect to any Person, any and all preferred or preference stock or other equity interests
(however designated) of such Person whether outstanding on the Issue Date or issued thereafter. 
 “principal” of a Note
means the principal of the Note plus, when appropriate, the premium, if any, on the Note. 
 “Private Placement
Legend” means the legends initially set forth on the Notes in the form set forth in Exhibit B. 
 “Purchase Money
Indebtedness” means Indebtedness, including Capitalized Lease Obligations, of the Issuer or any Restricted Subsidiary incurred for the purpose of financing all or any part of the purchase price of property, plant or equipment used in the
business of the Issuer or any Restricted Subsidiary or the cost of installation, construction or improvement 

  
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thereof; provided, however, that (1) the amount of such Indebtedness shall not exceed such purchase price or cost, (2) such Indebtedness shall not be secured by any asset
other than the specified asset being financed or, in the case of real property or fixtures, including additions and improvements, the real property to which such asset is attached and (3) such Indebtedness shall be incurred within one hundred
eighty (180) days before or after such acquisition of such asset by the Issuer or such Restricted Subsidiary or such installation, construction or improvement. 

“Qualified Equity Interests” means Equity Interests of the Issuer other than Disqualified Equity Interests. 

“Qualified Equity Offering” means the issuance and sale of Qualified Equity Interests of the Issuer. 

“Qualified Institutional Buyer” or “QIB” shall have the meaning specified in Rule 144A. 

“Record Date” means the applicable Record Date specified in the Notes; provided, however, that if any such date
is not a Business Day, the Record Date shall be the first (1st) day immediately succeeding such specified day that is a Business Day. 

“redeem” means to redeem, repurchase, purchase, defease, discharge or otherwise acquire or retire for value, and
“redemption” has a correlative meaning; provided, however, that this definition shall not apply for purposes of Section 5, Section 6 or Section 7 of the Notes, Article Three or Section 4.06(i). 

“Redemption Date,” when used with respect to any Note to be redeemed, means the date fixed for such redemption pursuant to
this Indenture and the Notes. 
 “Redemption Price,” when used with respect to any Note to be redeemed, means the price
fixed for such redemption, payable in immediately available funds, pursuant to this Indenture and the Notes. 
 “refinance”
means to refinance, repay, prepay, replace, renew or refund. 
 “Refinancing Indebtedness” means Indebtedness of the Issuer
or a Restricted Subsidiary issued in exchange for, or the proceeds from the issuance and sale or disbursement of which are used substantially concurrently to redeem or refinance in whole or in part, or constituting an amendment of, any Indebtedness
of the Issuer or any Restricted Subsidiary (the “Refinanced Indebtedness”); provided, however, that: 
 (1)
the principal amount (or accreted value, in the case of Indebtedness issued at a discount) of the Refinancing Indebtedness does not exceed the principal amount (or accreted value, as the case may be) of the Refinanced Indebtedness plus the
amount of accrued and unpaid interest on the Refinanced Indebtedness, any premium paid to the holders of the Refinanced Indebtedness and reasonable expenses incurred in connection with the incurrence of the Refinancing Indebtedness; 

  
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 (2) the Refinancing Indebtedness is the obligation of the same Person as that of the Refinanced
Indebtedness; 
 (3) if the Refinanced Indebtedness was subordinated in right of payment to the Notes or the Guarantees, as the case may be,
then such Refinancing Indebtedness, by its terms, is subordinate in right of payment to the Notes or the Guarantees, as the case may be, at least to the same extent as the Refinanced Indebtedness; 

(4) the Refinancing Indebtedness is scheduled to mature either (i) no earlier than the Refinanced Indebtedness being repaid or amended or
(ii) after the Maturity Date; 
 (5) the portion, if any, of the Refinancing Indebtedness that is scheduled to mature on or prior to
the Maturity Date has a Weighted Average Life to Maturity at the time such Refinancing Indebtedness is incurred that is equal to or greater than the Weighted Average Life to Maturity of the portion of the Refinanced Indebtedness being repaid that is
scheduled to mature on or prior to the Maturity Date; and 
 (6) the Refinancing Indebtedness is secured only to the extent, if at all, and
by the assets, that the Refinanced Indebtedness being repaid or amended is secured. 
 “Regulation S” means Regulation S
under the Securities Act. 
 “Regulation S Legend” means the legend initially set forth on the Regulation S Global Notes or
Physical Notes representing Notes sold to Non-U.S. Persons in reliance on Regulation S in the form set forth in Exhibit B. 

“Representative” means any agent or representative in respect of any Designated Senior Debt; provided, however,
that if, and for so long as, any Designated Senior Debt lacks such representative, then the Representative for such Designated Senior Debt shall at all times constitute the holders of a majority in outstanding principal amount of such Designated
Senior Debt. 
 “Responsible Officer” means, when used with respect to the Trustee, any officer in the Corporate Trust
Office or equivalent office, group or department of the Trustee to whom any corporate trust matter is referred because of such officer’s knowledge of and familiarity with the particular subject and shall also mean any officer who shall have
direct responsibility for the administration of this Indenture. 
 “Restricted Payment” means any of the following: 

(1) the declaration or payment of any dividend or any other distribution on Equity Interests of the Issuer or any Restricted Subsidiary or any
payment made to the direct or indirect holders (in their capacities as such) of Equity Interests of the Issuer or any Restricted Subsidiary (in respect of such Equity Interests) by the Issuer or any Restricted Subsidiary, including any payment in
connection with any merger or consolidation involving the Issuer, but excluding (i) dividends, distributions or payments payable or paid solely in Qualified Equity Interests (and payments of cash in lieu of delivering fractional shares in
connection therewith) and (ii) in the case of Restricted Subsidiaries, dividends, distributions or payments payable or paid to the Issuer or to a Restricted Subsidiary and pro rata dividends or distributions payable to minority
stockholders of any Restricted Subsidiary; 

  
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 (2) the redemption of any Equity Interests of the Issuer or any Restricted Subsidiary, including
any payment by the Issuer or any Restricted Subsidiary in connection with any merger or consolidation involving the Issuer, but excluding (i) any such Equity Interests held by the Issuer or any Restricted Subsidiary and (ii) any
redemptions to the extent payable or paid in Equity Interests of the Issuer or of an acquirer of the Issuer (and payments of cash in lieu of delivering fractional shares in connection therewith), in either case in this clause (ii) other than
Disqualified Equity Interests; 
 (3) any Investment other than a Permitted Investment; or 

(4) any redemption prior to the scheduled maturity or prior to any scheduled repayment of principal or sinking fund payment, as the case may
be, in respect of Subordinated Indebtedness, but excluding (i) any redemptions to the extent payable or paid in Qualified Equity Interests (and payments of cash in lieu of delivering fractional shares in connection therewith), (ii) any
redemptions of any Indebtedness the incurrence of which is permitted pursuant to Section 4.07(b)(5), or (iii) any redemption of Indebtedness of the Issuer or any Restricted Subsidiary purchased in anticipation of satisfying a sinking fund
obligation, principal installment or final maturity, in each case due within one year of such redemption. 
 “Restricted
Security” means a Note that constitutes a “restricted security” within the meaning of Rule 144(a)(3) under the Securities Act; provided, however, that the Trustee shall be entitled to request and conclusively rely on an Opinion of
Counsel (which shall be at the expense of the Issuer) with respect to whether any Note constitutes a Restricted Security. 

“Restricted Subsidiary” means any Subsidiary of the Issuer other than an Unrestricted Subsidiary. 

“Rule 144A” means Rule 144A under the Securities Act. 

“S&P” means Standard & Poor’s Ratings Services, a division of The McGraw-Hill Companies, Inc., and its
successors. 
 “Sale and Leaseback Transactions” means with respect to any Person an arrangement with any bank, insurance
company or other lender or investor or to which such lender or investor is a party, providing for the leasing by such Person of any asset of such Person which has been or is being sold or transferred by such Person to such lender or investor or to
any Person to whom funds have been or are to be advanced by such lender or investor on the security of such asset. 
 “SEC”
means the U.S. Securities and Exchange Commission. 
 “Secretary’s Certificate” means a certificate signed by the
Secretary or Assistant Secretary of the Issuer. 
 “Secured Indebtedness” of any Person at any date means Indebtedness of
such Person that is secured by a Lien on any assets of such Person or any of its Restricted Subsidiaries. 

  
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 “Securities Act” means the U.S. Securities Act of 1933, as amended. 

“Senior Debt” means the principal of, premium, if any, and interest (including any interest accruing subsequent to the filing
of a petition of bankruptcy at the rate provided for in the documentation with respect thereto, whether or not such interest is an allowed claim under applicable law) on any Indebtedness of the Issuer, whether outstanding on the Issue Date or
thereafter created, incurred or assumed, unless, in the case of any particular Indebtedness, the instrument creating or evidencing the same or pursuant to which the same is outstanding expressly provides that such Indebtedness shall not be senior in
right of payment to the Notes. 
 Without limiting the generality of the foregoing, “Senior Debt” shall also include the principal
of, premium, if any, and interest (including any interest accruing subsequent to the filing of a petition of bankruptcy at the rate provided for in the documentation with respect thereto, whether or not such interest is an allowed claim under
applicable law) on, and all other amounts owing in respect of: 
 (1) all obligations of every nature of the Issuer under, or with respect
to, any Credit Facility (including any Credit Agreement), including obligations to pay principal and interest, reimbursement obligations under letters of credit, fees, expenses and indemnities (and guarantees thereof), and including all obligations
under guarantees of the Issuer under or with respect to any of the foregoing or otherwise under or with respect to any Credit Facility (including any Credit Agreement); 

(2) all obligations of every nature of the Issuer under, or with respect to, any Hedging Obligations in respect of any Credit Facility
(including any Credit Agreement); and 
 (3) all obligations of every nature of the Issuer under, or with respect to, the Senior Notes; 

in each case, whether outstanding on the Issue Date or thereafter incurred. 

Notwithstanding the foregoing, “Senior Debt” shall not include: 

(1) any Indebtedness of the Issuer to any of its Subsidiaries; 

(2) Indebtedness to, or guaranteed on behalf of, any director, officer or employee of the Issuer or any of its Subsidiaries (including amounts
owed for compensation); 
 (3) obligations to trade creditors and other amounts incurred (but not under any Credit Facility (including any
Credit Agreement)) in connection with obtaining goods, materials or services; 
 (4) Indebtedness represented by Disqualified Equity
Interests; 
 (5) any liability for taxes owed or owing by the Issuer; 

(6) that portion of any Indebtedness incurred in violation of this Indenture (but, as to any such obligation, no such violation shall be
deemed to exist for purposes of this clause (6) if 

  
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the holder(s) of such obligation or their representative shall have received an Officers’ Certificate (or representation or warranty) of the Issuer to the effect that the incurrence of such
Indebtedness does not (or, in the case of revolving credit indebtedness, the incurrence of the entire committed amount thereof at the date on which the initial borrowing thereunder is made would not) violate the provisions of this Indenture); 

(7) Indebtedness which, when incurred and without respect to any election under Section 1111(b) of Title 11, United States Code, is
without recourse to the Issuer; 
 (8) Indebtedness under or evidenced by the 2007 Convertible Notes and any Indebtedness that expressly
provides that it ranks pari passu in right of payment with the 2007 Convertible Notes; 
 (9) Indebtedness under or evidenced by the
Existing Senior Subordinated Notes and any Indebtedness that expressly provides that it ranks pari passu in right of payment with any Existing Senior Subordinated Notes; and 

(10) any Indebtedness (including any Pari Passu Indebtedness or Subordinated Indebtedness) which is, by its express terms, subordinated in
right of payment to any other Indebtedness of the Issuer. 
 “Senior Notes” means those certain 7.250% senior notes due
2018 issued by the Issuer to certain holders thereof under the Senior Notes Indenture. 
 “Senior Notes Indenture” means
that certain Indenture between the Issuer and The Bank of New York Mellon Trust Company, N.A., as trustee, dated as of August 11, 2009, as amended, supplemented and modified by that certain Fifteenth Supplemental Indenture among the Issuer, the
guarantors named therein and The Bank of New York Mellon Trust Company, N.A., as trustee, dated as of December 11, 2012, as the foregoing has been further amended, supplemented and modified to date and may be further amended, supplemented and
modified. 
 “Series B Preferred Stock” means the Series B Convertible Perpetual Preferred Stock, par value $0.001 per
share, of the Issuer. 
 “Significant Subsidiary” means (1) any Restricted Subsidiary that would be a
“significant subsidiary” as defined in Regulation S-X promulgated pursuant to the Securities Act as such Regulation is in effect on the Issue Date and (2) any Restricted Subsidiary that, when aggregated with all other Restricted
Subsidiaries that are not otherwise Significant Subsidiaries and as to which any event described under Section 6.01(6) or Section 6.01(7) has occurred and is continuing, would constitute a Significant Subsidiary under clause (1) of
this definition. 
 “Stated Maturity” means, with respect to any installment of interest or principal on any Indebtedness,
the date on which such payment of interest or principal is scheduled to be paid in the documentation governing such Indebtedness, and shall not include any contingent obligations to repay, redeem or repurchase any such interest or principal prior to
the date originally scheduled for the payment thereof. 

  
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 “Subordinated Indebtedness” means Indebtedness of the Issuer or any Restricted
Subsidiary that is subordinated in right of payment to the Notes or the Guarantees, respectively. 
 “Subsidiary” means,
with respect to any Person: 
 (1) any corporation, limited liability company, association or other business entity of which more than 50%
of the total voting power of the Equity Interests entitled (without regard to the occurrence of any contingency) to vote in the election of the Board of Directors thereof are at the time owned or controlled, directly or indirectly, by such Person or
one or more of the other Subsidiaries of that Person (or a combination thereof); and 
 (2) any partnership (i) the sole general
partner or the managing general partner of which is such Person or a Subsidiary of such Person or (ii) the only general partners of which are such Person or of one or more Subsidiaries of such Person (or any combination thereof). 

Unless otherwise specified, “Subsidiary” refers to a Subsidiary of the Issuer. Based on the capital structure and ownership of the
P&G JV Companies as of the Issue Date, the P&G JV Companies are not Subsidiaries of the Issuer. 
 “Transaction
Date” has the meaning assigned to such term in the definition of “Consolidated Interest Coverage Ratio.” 

“Trust Indenture Act” means the Trust Indenture Act of 1939, as amended. 

“Trustee” means the Person named as the “Trustee” in the first paragraph of this instrument until a successor
Trustee shall have become such pursuant to the applicable provisions of this Indenture, and thereafter “Trustee” shall mean each Person who is then a Trustee hereunder. 

“Unrestricted Subsidiary” means (1) any Subsidiary that at the time of determination shall be designated an Unrestricted
Subsidiary by the Board of Directors of the Issuer in accordance with Section 4.16 and (2) any Subsidiary of an Unrestricted Subsidiary. As of the Issue Date, no Subsidiary has been designated by the Board of Directors of the Issuer as an
Unrestricted Subsidiary. 
 “U.S. Government Obligations” means direct, non-callable obligations of, or obligations
guaranteed by, the United States of America, and the payment for which the United States pledges its full faith and credit. 

“Voting Stock” with respect to any Person, means securities of any class of Equity Interests of such Person entitling the
holders thereof (whether at all times or only so long as no senior class of stock or other relevant equity interest has voting power by reason of any contingency) to vote in the election of members of the Board of Directors of such Person. 

“Weighted Average Life to Maturity” when applied to any Indebtedness at any date, means the number of years obtained by
dividing (1) the sum of the products obtained by multiplying (a) the amount of each then remaining installment, sinking fund, serial maturity or other required payment of principal, including payment at final maturity, in respect thereof
by (b) the number of years (calculated to the nearest one twelfth) that will elapse between such date and the making of such payment by (2) the then outstanding principal amount of such Indebtedness. 

  
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 “Wholly-Owned Restricted Subsidiary” means a Restricted Subsidiary of which 100%
of the Equity Interests (except for directors’ qualifying shares or certain minority interests owned by other Persons solely due to local law requirements that there be more than one stockholder, but which interest is not in excess of what is
required for such purpose) are owned directly by the Issuer or through one or more Wholly-Owned Restricted Subsidiaries. 
 SECTION 1.03 Other
Definitions. 
  

			
	 TERM
	  	DEFINED IN
SECTION
	 “Acceleration Notice”
	  	6.02
	 “Additional Notes”
	  	2.02
	 “Affiliate Transaction”
	  	4.11
	 “Authentication Order”
	  	2.02
	 “Base Indenture”
	  	Recitals
	 “Change of Control Offer”
	  	4.06
	 “Change of Control Payment Date”
	  	4.06
	 “Change of Control Purchase Price”
	  	4.06
	 “Covenant Defeasance”
	  	8.02
	 “Covenant Suspension Event”
	  	4.19
	 “Coverage Ratio Exception”
	  	4.07
	 “Designation”
	  	4.16
	 “Designation Amount”
	  	4.16
	 “Designated Non-Cash Consideration
	  	4.10
	 “Event of Default”
	  	6.01
	 “Excess Proceeds”
	  	4.10
	 “Global Notes”
	  	2.01
	 “Guarantee Obligations”
	  	11.01
	 “IAI Global Note”
	  	2.01
	 “Indenture”
	  	Recitals
	 “Initial Global Notes”
	  	2.01
	 “Initial Notes”
	  	2.02
	 “Investment Grade Rating
	  	4.19
	 “Legal Defeasance”
	  	8.02
	 “Net Proceeds Deficiency”
	  	4.10
	 “Net Proceeds Offer”
	  	4.10
	 “Net Proceeds Payment Date”
	  	4.10
	 “Non-Payment Default”
	  	10.02
	 “Offered Price”
	  	4.10
	 “Pari Passu Indebtedness Price”
	  	4.10
	 “Participants”
	  	2.15
	 “Paying Agent”
	  	2.03
	 “Payment Amount”
	  	4.10
	 “Payment Blockage Notice”
	  	10.02

  
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	 “Payment Blockage Period”
		10.02
	 “Payment Default”
		10.02
	 “Permitted Indebtedness”
		4.07
	 “Physical Notes”
		2.01
	 “Rating Agencies”
		4.19
	 “Redesignation”
		4.16
	 “Registrar”
		2.03
	 “Regulation S Global Note”
		2.01
	 “Restricted Payments Basket”
		4.08
	 “Reversion Date”
		4.19
	 “Successor”
		5.01
	 “Suspended Covenants”
		4.19
	 “Suspension Date”
		4.19
	 “Suspension Period”
		4.19

 SECTION 1.04 Incorporation by Reference of Trust Indenture Act. 

Whenever this Indenture refers to a provision of the Trust Indenture Act, such provision is incorporated by reference in, and made a part of,
this Indenture. The following Trust Indenture Act terms used in this Indenture have the following meanings: 
 “indenture
securities” means the Notes. 
 “obligor” on the indenture securities means the Issuer, any Guarantor or any other
obligor on the Notes. 
 All other Trust Indenture Act terms used in this Indenture that are defined by the Trust Indenture Act, defined by
Trust Indenture Act reference to another statute or defined by SEC rule and not otherwise defined herein have the meanings assigned to them therein. 

SECTION 1.05 Rules of Construction. 

Unless the context otherwise requires: 

(1) a term has the meaning assigned to it; 

(2) an accounting term not otherwise defined has the meaning assigned to it in accordance with GAAP; 

(3) “or” is not exclusive; 

(4) words in the singular include the plural, and words in the plural include the singular; 

(5) all references in this Indenture to “Articles,” “Sections” and other subdivisions are to the designated
Articles, Sections and provisions of this Indenture, unless otherwise indicated; 

  
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 (6) provisions apply to successive events and transactions; 

(7) “herein,” “hereof” and other words of similar import refer to this Indenture as a whole and not to any
particular Article, Section or other subdivision; and 
 (8) the words “including,” “includes” and
similar words shall not be limiting and shall be deemed to be followed by “without limitation.” 
 ARTICLE TWO 

THE NOTES 
 Pursuant to Article
Two of the Base Indenture, the provisions of this Article Two and the other provisions of this Supplemental Indenture establish the form and terms of the Notes and the Guarantees under this Supplemental Indenture. 

SECTION 2.01 Form and Dating. 
 The
Notes and the Trustee’s certificate of authentication shall be substantially in the form of Exhibit A hereto. The Notes may have notations, legends or endorsements required by law, stock exchange rule or usage. The Issuer shall approve the form
of the Notes and any notation, legend or endorsement on them. Each Note shall be dated the date of its issuance and show the date of its authentication. 

The terms and provisions contained in the Notes shall constitute, and are hereby expressly made, a part of this Indenture and, to the extent
applicable, the Issuer, the Guarantors and the Trustee, by their execution and delivery of this Indenture, expressly agree to such terms and provisions and to be bound thereby. 

Notes offered and sold in reliance on Rule 144A shall be issued initially in the form of a single permanent global Note in registered form,
substantially in the form set forth in Exhibit A (the “144A Global Note”), deposited with the Trustee, as custodian for the Depository, duly executed by the Issuer and authenticated by the Trustee as hereinafter provided and shall
bear the legends set forth in Exhibit B. 
 Notes offered and sold in offshore transactions in reliance on Regulation S shall be issued
initially in the form of a single permanent global Note in registered form, substantially in the form of Exhibit A (the “Regulation S Global Note”), deposited with the Trustee, as custodian for the Depository, duly executed by the
Issuer and authenticated by the Trustee as hereinafter provided and shall bear the legends set forth in Exhibit B. 
 The initial offer and
resale of the Notes shall not be to an Institutional Accredited Investor. The Notes resold to Institutional Accredited Investors in connection with the first transfer made pursuant to Section 2.16(a) shall be issued initially in the form of a
single permanent global Note in registered form, substantially in the form set forth in Exhibit A (the “IAI Global Note,” and, together with the 144A Global Note and the Regulation S Global Note, the “Initial Global
Notes”), deposited with the Trustee, as custodian for the Depository, duly executed by the Issuer and authenticated by the Trustee as hereinafter provided and shall bear the legends set forth in Exhibit B. 

  
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 Notes issued after the Issue Date shall be issued initially in the form of one or more global
Notes in registered form, substantially in the form set forth in Exhibit A, deposited with the Trustee, as custodian for the Depository, duly executed by the Issuer and authenticated by the Trustee as hereinafter provided and shall bear the
applicable legends set forth in Exhibit B and any legends required by applicable law (together with the Initial Global Notes, the “Global Notes”). 

The aggregate principal amount of the Global Notes may from time to time be increased or decreased by adjustments made on the records of the
Trustee, as custodian for the Depository, as hereinafter provided. Notes issued in exchange for interests in a Global Note pursuant to Section 2.16 may be issued in the form of permanent certificated Notes in registered form in substantially
the form set forth in Exhibit A and bearing the Private Placement Legend or the Regulation S Legend, in each case if applicable, and any legends required by applicable law (the “Physical Notes”). 

SECTION 2.02 Execution, Authentication and Denomination; Additional Notes. 

One Officer of the Issuer (who shall have been duly authorized by all requisite corporate actions) shall sign the Notes on behalf of the Issuer
by manual or facsimile signature. 
 If an Officer whose signature is on a Note was an Officer at the time of such execution but no longer
holds that office at the time the Trustee authenticates such Note, such Note shall nevertheless be valid. 
 A Note shall not be valid until
an authorized signatory of the Trustee manually signs the certificate of authentication on the Note. The signature shall be conclusive evidence that the Note has been authenticated under this Indenture. 

The Trustee shall authenticate (i) on the Issue Date, Notes for original issue in an aggregate principal amount not to exceed
$425,000,000 (the “Initial Notes”), and (ii) so long as not otherwise prohibited by the terms of this Indenture, including Section 4.07, additional Notes in an unlimited principal amount (the “Additional
Notes”), in each case upon a written order of the Issuer in the form of a certificate of an Officer of the Issuer (an “Authentication Order”). Each such Authentication Order shall specify the amount of Notes to be
authenticated and the date on which the Notes are to be authenticated, whether the Notes are to be Initial Notes or Additional Notes and whether the Notes are to be issued as certificated Notes or Global Notes and such other information as the
Trustee may reasonably request. In addition, with respect to authentication pursuant to clause (ii) of the first sentence of this paragraph, such Authentication Order from the Issuer (i) shall certify that such issuance is in compliance
with Section 4.07 and is otherwise permitted by the terms of the Indenture and (ii) shall be accompanied by an Opinion of Counsel of the Issuer in a form reasonably satisfactory to the Trustee. 

Notes may be issued in one or more series (with all of the Notes of any one series to be substantially identical except as to denomination),
and Additional Notes may have an issue date, issue price, aggregate principal amount or first interest payment date different from those of the 

  
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Initial Notes or any other Additional Notes. Any Additional Notes that are not fungible with the Initial Notes or any other Additional Notes for United States federal income tax purposes shall
constitute a separate issue and shall carry a separate “CUSIP” or “ISIN” number. Notwithstanding the foregoing, all Notes issued under this Indenture shall be treated as a single class for all purposes under this Indenture,
including for purposes of voting with respect to consents, waivers and amendments regarding this Indenture or the Notes and redemptions of and offers to purchase the Notes. The Notes shall bear any legend required by applicable law. 

The Trustee may appoint an authenticating agent reasonably acceptable to the Issuer to authenticate Notes. Unless otherwise provided in the
appointment, an authenticating agent may authenticate Notes whenever the Trustee may do so. Each reference in this Indenture to authentication by the Trustee includes authentication by such agent. An authenticating agent has the same rights as an
Agent to deal with the Issuer and Affiliates of the Issuer. The Trustee shall have the right to decline to authenticate and deliver any Notes under this Indenture if the Trustee, being advised by counsel, determines that such action may not lawfully
be taken or if the Trustee in good faith shall determine that such action would expose the Trustee to personal liability. 
 The Notes shall
be issuable in registered form without coupons in minimum denominations of $2,000 and integral multiples of $1,000. 
 SECTION 2.03 Registrar and
Paying Agent. 
 The Issuer shall maintain or cause to be maintained an office or agency in the Borough of Manhattan, The City of New
York, New York where (a) Notes may be presented or surrendered for registration of transfer or exchange (“Registrar”) and (b) Notes may, subject to Section 2 of the Notes, be presented or surrendered for payment
(“Paying Agent”). The Issuer may act as Registrar or Paying Agent, except that for the purposes of Articles Three and Eight and Section 4.06 and Section 4.10, neither the Issuer nor any Affiliate of the Issuer shall act as
Paying Agent. The Registrar shall keep a register of the Notes and of their transfer and exchange. The term “Registrar” includes any co-registrar and the term “Paying Agent” includes any additional paying agent. The Issuer hereby
appoints the Trustee as the initial Registrar and Paying Agent for the Notes and the Trustee hereby agrees to so act. The Issuer will give prompt written notice to the Trustee of the name and address, and any change in the name or address, of each
Registrar and Paying Agent. If at any time the Issuer shall fail to maintain any such required Registrar and Paying Agent or shall fail to furnish the Trustee with the name and address thereof, such presentations, surrenders, notices and demands may
be made or served at the Corporate Trust Office of the Trustee, and the Issuer hereby appoints the Trustee as its agent to receive all such presentations, surrenders, notices and demands and the Trustee hereby agrees to so act. 

The Issuer shall enter into an appropriate agency agreement with any Agent not a party to this Indenture, which agreement shall implement the
provisions of this Indenture that relate to such Agent. 
 The Issuer may also from time to time designate one or more co-registrars or
additional paying agents and may from time to time rescind such designations; provided, however, that no such designation or rescission shall in any manner relieve the Issuer of its obligations to maintain a Registrar and Paying Agent
in the place so specified above for such purposes. The Issuer will give prompt written notice to the Trustee of any such designation or rescission and of any change in the name or address of any such co-registrar or additional paying agent. 

  
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 Notices and demands to or upon the Issuer in respect of the Notes and this Indenture may be
served to the Issuer at its address set forth in Section 12.02. 
 SECTION 2.04 Paying Agent to Hold Assets in Trust. 

The Trustee as Paying Agent shall, and the Issuer shall require each Paying Agent other than the Trustee or the Issuer or any Subsidiary to
agree in writing that it shall, subject to Article Ten and Section 11.02, hold in trust for the benefit of Holders or the Trustee all assets held by the Paying Agent for the payment of principal of, or interest on, the Notes (whether such
assets have been distributed to it by the Issuer or any other obligor on the Notes), and shall notify the Trustee of any Default by the Issuer (or any other obligor on the Notes) in making any such payment. The Issuer at any time may require a
Paying Agent to distribute all assets held by it to the Trustee and account for any assets disbursed, and the Trustee may at any time during the continuance of any payment Default, upon written request to a Paying Agent, require such Paying Agent to
distribute all assets held by it to the Trustee and to account for any assets distributed. Upon distribution to the Trustee of all assets that shall have been delivered by the Issuer to the Paying Agent, the Paying Agent shall have no further
liability for such assets. If the Issuer or a Subsidiary of the Issuer acts as Paying Agent, it shall segregate and hold in a separate trust fund for the benefit of the Holders of the Notes all money held by it as Paying Agent. 

SECTION 2.05 Holder Lists. 
 The
Trustee shall preserve in as current a form as is reasonably practicable the most recent list available to it of the names and addresses of Holders of the Notes and shall otherwise comply with Trust Indenture Act § 312(a). If the Trustee is not
the Registrar, the Issuer shall furnish to the Trustee at least two (2) Business Days prior to each Interest Payment Date and at such other times as the Trustee may request in writing a list, in such form and as of such date as the Trustee may
reasonably require, of the names and addresses of Holders, which list may be conclusively relied upon by the Trustee. 
 SECTION 2.06 Transfer and
Exchange. 
 Subject to Sections 2.15 and 2.16, when Notes are presented to the Registrar with a request to register the transfer of such
Notes or to exchange such Notes for an equal principal amount of Notes of other authorized denominations, the Registrar shall register the transfer or make the exchange as requested if its requirements for such transaction are met;
provided, however, that the Notes surrendered for transfer or exchange shall be duly endorsed or accompanied by a written instrument of transfer in form satisfactory to the Issuer and the Registrar, duly executed by the Holder thereof
or his or her attorney duly authorized in writing. To permit registrations of transfers and exchanges, the Issuer shall execute and the Trustee shall authenticate Notes at the Registrar’s request. No service charge shall be made for any
registration of transfer or exchange (except as otherwise expressly permitted herein), but the Issuer or Trustee may require payment of a sum sufficient to cover any transfer tax or similar governmental charge payable in connection therewith (other
than any such transfer tax or similar governmental charge payable upon exchanges pursuant to Section 2.10, 3.06 or 9.06). 

  
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 Without the prior written consent of the Issuer, the Registrar shall not be required to register
the transfer of or exchange of any Note (i) during the period beginning at the opening of business fifteen (15) days before the mailing of a notice of redemption of Notes and ending at the close of business on the day of such mailing,
(ii) selected for redemption in whole or in part pursuant to Article Three, except the unredeemed portion of any Note being redeemed in part, and (iii) beginning at the opening of business on any Record Date and ending on the close of
business on the related Interest Payment Date. 
 Any Holder of a beneficial interest in a Global Note shall, by acceptance of such
beneficial interest, agree that transfers of beneficial interests in such Global Notes may be effected only through a book-entry system maintained by the Depository or other Person that is the Holder of such Global Note (or its agent) in accordance
with the applicable legends thereon, and that ownership of a beneficial interest in the Note shall be required to be reflected in a book-entry system. 

SECTION 2.07 Replacement Notes. 
 If
a mutilated Note is surrendered to the Trustee or if the Holder of a Note claims that the Note has been lost, destroyed or wrongfully taken, the Issuer shall issue and the Trustee shall authenticate and deliver a replacement Note if the requirements
of Section 8-405 of the Uniform Commercial Code are met and the Holder satisfies any other reasonable requirements of the Trustee. Such Holder shall furnish an indemnity bond sufficient in the judgment of the Issuer and the Trustee to protect
the Issuer, the Trustee or any Agent from any loss which any of them may suffer if a Note is replaced. The Issuer and the Trustee may charge such Holder for its reasonable out-of-pocket expenses in replacing a Note pursuant to this
Section 2.07, including reasonable fees and expenses of counsel and of the Trustee. 
 Every replacement Note issued pursuant to this
Section in lieu of any lost, destroyed or wrongfully taken Note shall constitute an original additional contractual obligation of the Issuer, whether or not the lost, destroyed or wrongfully taken Note shall be at any time enforceable by anyone, and
shall be entitled to all the benefits of this Indenture equally and proportionately with any and all other Notes duly issued hereunder. 

In case any such mutilated, destroyed, lost or wrongfully taken Note has become or is about to become due and payable, the Issuer in its
discretion may, instead of issuing a new Note, pay such Note. 
 The provisions of this Section 2.07 are exclusive and shall preclude
(to the extent lawful) all other rights and remedies with respect to the replacement or payment of lost, destroyed or wrongfully taken Notes. 

SECTION 2.08 Outstanding Notes. 

Subject to Section 2.09, the Notes outstanding at any time are all the Notes that have been authenticated by the Trustee except those
cancelled by it, those paid pursuant to Section 2.07, 

  
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delivered to it for cancellation and those described in this Section as not outstanding. Subject to Section 2.09, a Note does not cease to be outstanding because the Issuer, the Guarantors
or any of their respective Affiliates hold the Note. 
 If a Note is replaced pursuant to Section 2.07 (other than a mutilated Note
surrendered for replacement), it ceases to be outstanding unless a Responsible Officer of the Trustee receives proof satisfactory to it that the replaced Note is held by a bona fide purchaser. A mutilated Note ceases to be outstanding upon
surrender of such Note and replacement thereof pursuant to Section 2.07. 
 If the principal amount of any Note is considered paid
under Section 4.01, it ceases to be outstanding and interest ceases to accrue. If on a Redemption Date or the Maturity Date the Trustee or Paying Agent (other than the Issuer or an Affiliate thereof) holds cash in Dollars or U.S. Government
Obligations, or a combination thereof, in amounts sufficient to pay all of the principal and interest due on the Notes payable on that date, then on and after that date such Notes cease to be outstanding and interest on them ceases to accrue. 

SECTION 2.09 Treasury Notes. 
 In
determining whether the Holders of the required principal amount of Notes have concurred in any request, demand, authorization, direction, notice, consent or waiver, Notes owned by the Issuer or an Affiliate of the Issuer shall be disregarded,
except that for, the purposes of determining whether the Trustee shall be protected in relying on any such request, demand, authorization, direction, notice, consent or waiver, only Notes that a Responsible Officer of the Trustee actually knows are
so owned shall be so disregarded. 
 SECTION 2.10 Temporary Notes. 

Until definitive Notes are ready for delivery, the Issuer may prepare and the Trustee shall authenticate temporary Notes. Temporary Notes shall
be substantially in the form of definitive Notes but may have variations that the Issuer considers appropriate for temporary Notes. Without unreasonable delay, the Issuer shall prepare and the Trustee shall authenticate definitive Notes in exchange
for temporary Notes. Until such exchange, temporary Notes shall be entitled to the same rights, benefits and privileges as definitive Notes. Notwithstanding the foregoing, so long as the Notes are represented by a Global Note, such Global Note may
be in typewritten form. 
 SECTION 2.11 Cancellation. 

The Issuer at any time may deliver Notes to the Trustee for cancellation. The Registrar and the Paying Agent shall forward to the Trustee any
Notes surrendered to them for transfer, exchange or payment. The Trustee, or at the direction of the Trustee, the Registrar or the Paying Agent (other than the Issuer or an Affiliate of the Issuer), and no one else, shall cancel and, at the written
direction of the Issuer, shall dispose of all Notes surrendered for transfer, exchange, payment or cancellation in accordance with its customary procedures. Certification of the destruction of all cancelled Notes shall be delivered to the Issuer
upon request by the Issuer. Subject to Section 2.07, the Issuer may not issue new Notes to replace Notes that it has paid or delivered to the Trustee for cancellation. If the Issuer or any Guarantor shall acquire any of the

  
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Notes, such acquisition shall not operate as a redemption or satisfaction of the Indebtedness represented by such Notes unless and until the same are surrendered to the Trustee for cancellation
pursuant to this Section 2.11. 
 SECTION 2.12 Defaulted Interest. 

If the Issuer defaults in a payment of interest on the Notes, it shall pay the defaulted interest, plus (to the extent lawful) any
interest payable on the defaulted interest, in any lawful manner. The Issuer may pay the defaulted interest to the Persons who are Holders on a subsequent special record date, which date shall be the fifteenth (15th) day next preceding the date
fixed by the Issuer for the payment of defaulted interest or the next succeeding Business Day if such date is not a Business Day. At least fifteen (15) days before any such subsequent special record date, the Issuer (or, upon the written
request of the Issuer, the Trustee in the name and at the expense of the Issuer) shall mail to each Holder, with a copy to the Trustee, a notice that states the subsequent special record date, the payment date and the amount of defaulted interest,
and interest payable on such defaulted interest, if any, to be paid. 
 SECTION 2.13 CUSIP and ISIN Numbers. 

The Issuer in issuing the Notes may use “CUSIP” or “ISIN” numbers, and if so, the Trustee shall use the “CUSIP”
or “ISIN” numbers in notices of redemption or exchange as a convenience to Holders; provided, however, that any such notice may state that no representation is made as to the correctness or accuracy of the “CUSIP”
or “ISIN” numbers printed in the notice or on the Notes, and that reliance may be placed only on the other identification numbers printed on the Notes. The Issuer will promptly notify the Trustee of any change in the “CUSIP” or
“ISIN” numbers. 
 SECTION 2.14 Deposit of Moneys. 

Subject to Section 2 of the Notes, prior to 10:00 a.m. New York City time on each Interest Payment Date, Maturity Date, Redemption Date,
Change of Control Payment Date and Net Proceeds Payment Date, the Issuer shall have deposited with the Paying Agent, in immediately available funds, funds in Dollars sufficient to make cash payments, if any, due on such Interest Payment Date,
Maturity Date, Redemption Date, Change of Control Payment Date and Net Proceeds Payment Date, as the case may be, in a timely manner which permits the Paying Agent to remit payment to the Holders on such Interest Payment Date, Maturity Date,
Redemption Date, Change of Control Payment Date and Net Proceeds Payment Date, as the case may be. 
 SECTION 2.15 Book-Entry Provisions for Global
Notes. 
 (a) The Global Notes initially shall (i) be registered in the name of the Depository or the nominee of such Depository,
(ii) be delivered to the Trustee as custodian for such Depository and (iii) bear legends as set forth in Exhibit B, as applicable. 

Members of, or participants in, the Depository (“Participants”) shall have no rights under this Indenture with respect to any
Global Note held on their behalf by the Depository, or 

  
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the Trustee as its custodian, or under the Global Note, and the Depository may be treated by the Issuer, the Trustee and any agent of the Issuer or the Trustee as the absolute owner of the Global
Note for all purposes whatsoever. Notwithstanding the foregoing, nothing herein shall prevent the Issuer, the Trustee or any agent of the Issuer or the Trustee from giving effect to any written certification, proxy or other authorization furnished
by the Depository or impair, as between the Depository and Participants, the operation of customary practices governing the exercise of the rights of a Holder of any Note. 

(b) The transfer and exchange of beneficial interests in Global Notes will be effected through the Depository, in accordance with the
provisions of this Indenture and the rules and procedures of the Depository that apply to such transfer or exchange. 
 (c) Transfers of
Global Notes shall be limited to transfers in whole, but not in part, to the Depository, its successors or their respective nominees. Interests of beneficial owners in the Global Notes may be transferred or exchanged for Physical Notes in accordance
with the rules and procedures of the Depository and the provisions of Section 2.16. In addition, Physical Notes shall be transferred to all beneficial owners in exchange for their beneficial interests in Global Notes if (i) the Depository
notifies the Issuer that it is unwilling or unable to act as Depository for any Global Note, the Issuer so notifies the Trustee in writing and a successor Depository is not appointed by the Issuer within ninety (90) days of such notice or
(ii) a Default has occurred and is continuing and the Registrar has received a written request from any owner of a beneficial interest in a Global Note to issue Physical Notes. Upon any issuance of a Physical Note in accordance with this
Section 2.15(c), the Trustee shall be required to register such Physical Note in the name of, and cause the same to be delivered to, such Person or Persons (or the nominee of any thereof). All such Physical Notes shall bear any legends required
by applicable law. 
 (d) In connection with any transfer or exchange of a portion of the beneficial interest in a Global Note to beneficial
owners pursuant to Section 2.15(c), the Registrar shall (if one or more Physical Notes are to be issued) reflect on its books and records the date and a decrease in the principal amount of such Global Note in an amount equal to the principal
amount of the beneficial interest in the Global Note to be transferred, and the Issuer shall execute, and the Trustee shall authenticate and deliver, one or more Physical Notes of authorized denominations in an aggregate principal amount equal to
the principal amount of the beneficial interest in the Global Note so transferred. 
 (e) In connection with the transfer of a Global Note
as an entirety to beneficial owners pursuant to Section 2.15(c), such Global Note shall be deemed to be surrendered to the Trustee for cancellation, and (i) the Issuer shall execute and (ii) the Trustee shall, upon written
instructions from the Issuer, authenticate and deliver to each beneficial owner identified by the Depository, in exchange for its beneficial interest in such Global Note, an equal aggregate principal amount of Physical Notes of authorized
denominations. 
 (f) Any Physical Note constituting a Restricted Security delivered in exchange for an interest in a Global Note pursuant
to paragraph (c) or (d) of this Section 2.15 shall, except as otherwise provided by Section 2.16, bear the Private Placement Legend or, to the extent such Physical Note represents Notes sold to a Non-U.S. Person in reliance on
Regulation S, a Regulation S Legend. 

  
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 (g) The Holder of any Global Note, including the Depository, may grant proxies, appoint agents
and otherwise authorize any Person, including Participants and Persons that may hold interests through Participants, to give or take any request, demand, authorization, direction, notice, consent, waiver or other action that a Holder is entitled to
take under this Indenture or the Notes. 
 (h) Except as provided in the last sentence of Section 2.08, the Issuer, the Trustee and any
Agent shall treat a Person as the Holder of such principal amount of outstanding Notes represented by a Global Note as shall be specified in a written statement of the Depository with respect to such Global Note, for purposes of obtaining any
consents, declarations, waivers or directions required to be given by the Holders pursuant to this Indenture. 
 SECTION 2.16 Special Transfer and
Exchange Provisions. 
 (a) Transfers to Non-QIB Institutional Accredited Investors. The following provisions shall apply with
respect to any proposed transfer of a Restricted Security to any Institutional Accredited Investor which is not a QIB: 
 (1)
the Registrar shall register the transfer of any Restricted Security, whether or not such Note bears the Private Placement Legend, if (x) the requested transfer is after the first anniversary of the original date of issuance of such Note (or
until an earlier transfer if (i) such Note is transferred following the six-month anniversary of the original date of issuance of such Note in accordance with this Indenture and (ii) the Issuer has at the time of such transfer filed all
required reports under Section 13 or 15(d) of the Exchange Act during the twelve-month period preceding the date of transfer), provided, however, that neither the Issuer nor any Affiliate of the Issuer has held any beneficial interest in such
Note, or portion thereof, at any time on or prior to the first anniversary of the original date of issuance of such Note (or until an earlier transfer if (i) such Note is transferred following the six-month anniversary of the original date of
issuance of such Note in accordance with this Indenture and (ii) the Issuer has at the time of such transfer filed all required reports under Section 13 or 15(d) of the Exchange Act during the
twelve-month period preceding the date of transfer) (it being understood that the Registrar shall have no responsibility to confirm whether the Issuer or its Affiliates so held any beneficial interest in such
Note, or portion thereof, during such time), or (y) the proposed transferee has delivered to the Registrar a certificate substantially in the form of Exhibit C hereto and any legal opinions and certifications as may be reasonably requested by
the Trustee or the Issuer; 
 (2) if the proposed transferee is a Participant and the Notes to be transferred consist of
Physical Notes which after transfer are to be evidenced by an interest in the IAI Global Note, upon receipt by the Registrar of the Physical Note and (x) written instructions given in accordance with the Depository’s and the
Registrar’s procedures and (y) the certificate, if required, referred to in clause (y) of paragraph (i) above (and any legal opinions or other certifications), the Registrar shall register the transfer and reflect on its books
and records the date of transfer and an increase in the principal amount of the IAI Global Note in an amount equal to the principal amount of Physical Notes to be transferred, and the Registrar or Trustee shall cancel the Physical Notes so
transferred; and 

  
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 (3) if the proposed transferor is a Participant seeking to transfer an interest
in a Global Note, upon receipt by the Registrar of (x) written instructions given in accordance with the Depository’s and the Registrar’s procedures and (y) the certificate, if required, referred to in clause (y) of
paragraph (i) above (and any legal opinions or other certifications), the Registrar shall register the transfer and reflect on its books and records the date of transfer and (A) a decrease in the principal amount of the Global Note from
which such interests are to be transferred in an amount equal to the principal amount of the Notes to be transferred and (B) an increase in the principal amount of the IAI Global Note in an amount equal to the principal amount of the Notes to
be transferred. 
 (b) Transfers to QIBs. The following provisions shall apply with respect to any proposed transfer of a Restricted
Security to a QIB: 
 (1) the Registrar shall register the transfer of any Restricted Security, whether or not such Note
bears the Private Placement Legend, if (x) the requested transfer is after the first anniversary of the original date of issuance of such Note (or until an earlier transfer if (i) such Note is transferred following the six-month
anniversary of the original date of issuance of such Note in accordance with this Indenture and (ii) the Issuer has at the time of such transfer filed all required reports under Section 13 or 15(d) of the Exchange Act during the
twelve-month period preceding the date of transfer); provided, however, that neither the Issuer nor any Affiliate of the Issuer has held any beneficial interest in such Note, or portion thereof, at any time on or prior to the first anniversary of
the original date of issuance of such Note (or until an earlier transfer if (i) such Note is transferred following the six-month anniversary of the original date of issuance of such Note in accordance with this Indenture and (ii) the
Issuer has at the time of such transfer filed all required reports under Section 13 or 15(d) of the Exchange Act during the twelve-month period preceding the date of transfer) (it being understood that the Registrar shall have no responsibility
to confirm whether the Issuer or its Affiliates so held any beneficial interest in such Note, or portion thereof, during such time) or (y) such transfer is being made by a proposed transferor who has checked the box provided for on the
applicable Global Note stating, or has otherwise advised the Issuer and the Registrar in writing, (1) that the sale has been made in compliance with the provisions of Rule 144A to a transferee who has signed the certification provided for on
the applicable Global Note stating, or has otherwise advised the Issuer and the Registrar in writing, that it is purchasing the Note for its own account or an account with respect to which it exercises sole investment discretion and that it and any
such account is a QIB within the meaning of Rule 144A, (2) that it is aware that the sale to it is being made in reliance on Rule 144A, and (3) that it acknowledges (A) that it has received such information regarding the Issuer as it
has requested pursuant to Rule 144A or has determined not to request such information and (B) that it is aware that the transferor is relying upon its foregoing representations in order to claim the exemption from registration provided by Rule
144A; 
 (2) if the proposed transferee is a Participant and the Notes to be transferred consist of Physical Notes which
after transfer are to be evidenced by an interest in the 144A Global Note, upon receipt by the Registrar of the Physical Note and written instructions given in accordance with the Depository’s and the Registrar’s procedures, the Registrar
shall register the transfer and reflect on its book and records the 

  
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date of transfer and an increase in the principal amount of the 144A Global Note in an amount equal to the principal amount of Physical Notes to be transferred, and the Registrar shall cancel the
Physical Notes so transferred; and 
 (3) if the proposed transferor is a Participant seeking to transfer an interest in the
IAI Global Note or the Regulation S Global Note, upon receipt by the Registrar of written instructions given in accordance with the Depository’s and the Registrar’s procedures, the Registrar shall register the transfer and reflect on its
books and records the date of transfer and (A) a decrease in the principal amount of the IAI Global Note or the Regulation S Global Note, as the case may be, in an amount equal to the principal amount of the Notes to be transferred and
(B) an increase in the principal amount of the 144A Global Note in an amount equal to the principal amount of the Notes to be transferred. 

(c) Transfers to Non-U.S. Persons. The following provisions shall apply with respect to any proposed transfer of a Restricted Security
to a Non-U.S. Person under Regulation S: 
 (1) the Registrar shall register any proposed transfer of any Restricted Security
to a Non-U.S. Person upon receipt of a certificate substantially in the form of Exhibit D from the proposed transferor and such certifications, legal opinions and other information as the Trustee or the Issuer may reasonably request; and 

(2) (a) if the proposed transferor is a Participant holding a beneficial interest in the Rule 144A Global Note or the IAI
Global Note or the Note to be transferred consists of Physical Notes, upon receipt by the Registrar of (x) any such Physical Note to be transferred and the documents required by paragraph (1) and (y) instructions in accordance with
the Depository’s and the Registrar’s procedures, the Registrar shall reflect on its books and records the date of transfer and a decrease in the principal amount of the Rule 144A Global Note or the IAI Global Note, as the case may be, in
an amount equal to the principal amount of the beneficial interest in the Rule 144A Global Note or the IAI Global Note, as the case may be, to be transferred or cancel the Physical Notes to be transferred, and (b) if the proposed transferee is
a Participant, upon receipt by the Registrar of any such Physical Note to be transferred and instructions given in accordance with the Depository’s and the Registrar’s procedures, the Registrar shall reflect on its books and records the
date of transfer and an increase in the principal amount of the Regulation S Global Note in an amount equal to the principal amount of the Rule 144A Global Note, the IAI Global Note or the Physical Notes, as the case may be, to be transferred. 

(d) Restrictions on Transfer and Exchange of Global Notes. Notwithstanding any other provisions of this Indenture, a Global Note may
not be transferred as a whole except by the Depository to a nominee of the Depository or by a nominee of the Depository to the Depository or another nominee of the Depository or by the Depository or any such nominee to a successor Depository or a
nominee of such successor Depository. 
 (e) Restrictive Legends. Unless (i) there is delivered to the Trustee an Opinion of
Counsel reasonably satisfactory to the Issuer and the Trustee to the effect that neither such legend nor the related restrictions on transfer are required in order to maintain compliance with the provisions of the Securities Act or (ii) such
Note has been offered and sold pursuant to an 

  
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effective registration statement under the Securities Act, (x) each Global Note and each Physical Note that constitutes a Restricted Security shall bear the Private Placement Legend set
forth in Exhibit B hereto on the face thereof and (y) each Regulation S Global Note and each Physical Note representing Notes sold to a Non-U.S. Person in reliance on Regulation S shall bear the Regulation S Legend set forth in Exhibit B
hereto. Upon the transfer, exchange or replacement of Notes not bearing the Private Placement Legend or the Regulation S Legend, unless otherwise required by applicable law, the Registrar shall deliver Notes that do not bear the Private Placement
Legend or the Regulation S Legend. 
 (f) General. By its acceptance of any Note bearing the Private Placement Legend or the
Regulation S Legend, each Holder of such a Note acknowledges the restrictions on transfer of such Note set forth in this Indenture, in the Private Placement Legend and the Regulation S Legend and agrees that it will transfer such Note only as
provided in this Indenture. 
 The Registrar shall retain copies of all letters, notices and other written communications received pursuant
to Section 2.15 or this Section 2.16. The Issuer shall have the right to inspect and make copies of all such letters, notices or other written communications at any reasonable time upon the giving of reasonable written notice to the
Registrar. Neither the Trustee nor the Registrar shall have any obligation or duty to monitor, determine or inquire as to compliance with any restrictions on transfer imposed under this Indenture or under applicable law with respect to any transfer
of any interest in any Note (including any transfers between or among Participants or beneficial owners of interests in any Global Note) other than to require delivery of such certificates and other documentation or evidence as are expressly
required by, and to do so if and when expressly required by the terms of, this Indenture, and to examine the same to determine substantial compliance as to form with the express requirements hereof. Neither the Trustee nor the Registrar shall have
any responsibility for the actions or omissions of the Depository, or the accuracy of the books and records of the Depository. 
 (g)
Cancellation and/or Adjustment of Global Note. At such time as all beneficial interests in a particular Global Note have been exchanged for Physical Notes or a particular Global Note has been redeemed, repurchased or canceled in whole and not
in part, each such Global Note shall be returned to or retained and canceled by the Trustee in accordance with Section 2.11. At any time prior to such cancellation, if any beneficial interest in a Global Note is exchanged for or transferred to
a Person who will take delivery thereof in the form of a beneficial interest in another Global Note or for Physical Notes, the principal amount of Notes represented by such Global Note shall be reduced accordingly and an endorsement shall be made on
such Global Note by the Trustee or by the Depository at the direction of the Trustee to reflect such reduction; and if the beneficial interest is being exchanged for or transferred to a Person who will take delivery thereof in the form of a
beneficial interest in another Global Note, such other Global Note shall be increased accordingly and an endorsement shall be made on such Global Note by the Trustee or by the Depository at the direction of the Trustee to reflect such increase. 

  
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 ARTICLE THREE 

REDEMPTION 
 SECTION 3.01 Notices to
Trustee. 
 If the Issuer elects to redeem Notes pursuant to Section 5, Section 6 or Section 7 of the Notes or
Section 4.06(i), it shall notify the Trustee of the Redemption Date, the Redemption Price and the principal amount of Notes to be redeemed. The Issuer shall give the notice of redemption to the Trustee at least forty-five (45) days (unless
a shorter notice shall be agreed to by the Trustee in writing) but not more than sixty (60) days before the applicable Redemption Date (except that a notice issued in connection with a redemption referred to in Article Eight may be more than
sixty (60) days before such Redemption Date), together with such documentation and records as shall enable the Trustee to select the Notes to be redeemed. 

SECTION 3.02 Selection of Notes to be Redeemed. 

If less than all of the Notes are to be redeemed at any time pursuant to Section 5, Section 6 or Section 7 of the Notes, the
Trustee shall select the Notes to be redeemed as follows: 
 (1) if the Notes are listed on a national securities exchange,
in compliance with the requirements of the principal national securities exchange on which the Notes are listed; or 
 (2) if
the Notes are not so listed, on a pro rata basis (if the Notes are issued in physical form), or in accordance with applicable procedures of the Depository (if the Notes are issued in global form); 

provided, however, that, in the case of such redemption, the Trustee will select the Notes on a pro rata basis or on as nearly a pro
rata basis as practicable (subject to the procedures of the Depository), unless that method is otherwise prohibited. 
 The Trustee
shall promptly notify the Issuer in writing of the Notes selected for redemption and, in the case of any Note selected for partial redemption, the principal amount thereof to be redeemed. Notes and portions of Notes selected shall be in the amounts
of $1,000 or integral multiples of $1,000; provided, however, that no Note shall be redeemed in part if such Note would have a remaining principal amount of less than $2,000; provided further, however, that that if all of
the Notes of a Holder are to be redeemed, the entire outstanding amount of the Notes held by such Holder, even if not an integral multiple of $1,000, shall be redeemed. Except as provided in the preceding sentence, provisions of this Indenture that
apply to the Notes called for redemption shall also apply to portions of Notes called for redemption. 
 SECTION 3.03 Notice of Redemption. 

At least thirty (30) days but not more than sixty (60) days before the applicable Redemption Date, the Issuer shall mail, or cause to
be mailed, a notice of redemption by first class mail, postage prepaid, to each Holder whose Notes are to be redeemed, at the Holder’s registered address (except that a notice issued in connection with a redemption referred to in Article Eight
may be more than sixty (60) days before such Redemption Date). At the Issuer’s written request, the Trustee shall forward the notice of redemption in the Issuer’s name and at the Issuer’s expense. Each notice for redemption shall
identify the Notes to be redeemed (including the CUSIP or ISIN number, if any) and shall state: 
 (1) the Redemption Date;

  
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 (2) the Redemption Price and the amount of accrued interest, if any, to be paid;

 (3) the name and address of the Paying Agent; 

(4) that Notes called for redemption must be surrendered to the Paying Agent to collect the Redemption Price plus
accrued interest, if any; 
 (5) that, unless the Issuer defaults in making the redemption payment, interest on Notes
called for redemption shall cease to accrue on and after the Redemption Date, and the only remaining right of the Holders of such Notes shall be to receive payment of the Redemption Price (together with accrued interest, if any, thereon to, but not
including, the Redemption Date) upon surrender to the Trustee or Paying Agent of the Notes redeemed; 
 (6) if any Note is
being redeemed in part, the portion of the principal amount of such Note to be redeemed and that, after the Redemption Date, and upon surrender and cancellation of such Note, a new Note or Notes in aggregate principal amount equal to the unredeemed
portion thereof will be issued; 
 (7) if fewer than all the Notes are to be redeemed, the identification of particular Notes
(or portion thereof) to be redeemed, as well as the aggregate principal amount of Notes to be redeemed and the aggregate principal amount of Notes to be outstanding after such partial redemption; and 

(8) the Section of the Notes or this Indenture, as applicable, pursuant to which the Notes are to be redeemed. 

The notice, if mailed in a manner herein provided, shall be conclusively presumed to have been given, whether or not the Holder receives such
notice. In any case, failure to give such notice by mail or any defect in the notice to the Holder of any Note designated for redemption in whole or in part shall not affect the validity of the proceedings for the redemption of any other Note.
Notices of redemption, if conditional, shall specify the conditions to the redemption described therein. 
 At the Issuer’s request,
the Trustee shall give the notice of redemption in the Issuer’s name and at its expense. 
 SECTION 3.04 Effect of Notice of Redemption.

 Once notice of redemption is mailed in accordance with Section 3.03, Notes called for redemption shall become due and payable on the
Redemption Date at the Redemption Price therefor plus accrued interest, if any, thereon to, but not including, the Redemption Date; provided that, any such redemption may, at the Issuer’s option, be subject to one or more
conditions precedent, including but not limited to the consummation of a Qualified Equity Offering or a Change of Control. Upon surrender to the Trustee or Paying Agent, such Notes called for redemption shall be paid at the Redemption Price plus
accrued interest, if any, thereon to, but not including, the Redemption Date, provided that installments of interest whose Stated 

  
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Maturity is on or prior to the Redemption Date shall be payable to the Holders of such Notes registered at the close of business on the relevant Record Dates. On and after the Redemption Date
interest shall cease to accrue on Notes or portions thereof called for redemption unless the Issuer shall have not complied with its obligations pursuant to Section 3.05. 

SECTION 3.05 Deposit of Redemption Price. 

On or before 10:00 a.m. New York time on the Redemption Date, the Issuer shall deposit with the Paying Agent funds in Dollars sufficient to pay
the Redemption Price of all Notes to be redeemed on that date plus all accrued and unpaid interest, if any, thereon to, but not including, the Redemption Date. 

If the Issuer complies with the preceding paragraph, then, unless the Issuer defaults in the payment of such Redemption Price (together with
all accrued and unpaid interest, if any, thereon to, but not including, the Redemption Date) with respect to the Notes to be redeemed, interest on such Notes will cease to accrue on and after the applicable Redemption Date, whether or not such Notes
are presented for payment. 
 SECTION 3.06 Notes Redeemed in Part. 

Upon surrender of a Note that is to be redeemed in part, the notice of redemption that relates to such Note shall state the portion of the
principal amount thereof to be redeemed. A new Note or Notes of the same Maturity Date and equal in principal amount to the unredeemed portion of the original Note or Notes shall be issued in the name of the Holder thereof upon surrender and
cancellation of the original Note or Notes surrendered. 
 ARTICLE FOUR 

COVENANTS 
 SECTION 4.01 Payment of
Principal and Interest. 
 The Issuer shall pay or cause to be paid the principal of and interest on the Notes in the manner provided in
the Notes and this Indenture. An installment of principal of, or interest on, the Notes shall be considered paid on the date it is due if the Trustee or the Paying Agent (other than the Issuer or an Affiliate thereof) holds by 10:00 a.m. New York
time on that date funds designated for and sufficient to pay the installment. The Paying Agent shall return to the Issuer promptly, and in any event, no later than five (5) Business Days following the date of payment, any money (including
accrued interest) that exceeds such amount of principal and interest paid on the Notes. If a payment date is not a Business Day, at a place of payment, payment may be made at that place on the next succeeding day that is a Business Day, and no
interest shall accrue on such payment for the intervening period. 
 The Issuer shall pay interest (including post petition interest in a
proceeding under any Bankruptcy Law), on overdue principal and premium, if any, and overdue interest (without regard to applicable grace periods), to the extent lawful, at the same rate per annum borne by the Notes. 

  
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 Interest on the Notes will be computed on the basis of a 360-day year comprised of twelve 30-day
months. 
 SECTION 4.02 Maintenance of Office or Agency. 

The Issuer covenants and agrees for the benefit of the Holders that it will maintain in the Borough of Manhattan, The City of New York, New
York the office or agency required under Section 2.03 (which may be an office or drop facility of the Trustee or the Registrar, as applicable, for such Notes or an Affiliate of such Trustee or the Registrar, as applicable, for such Notes) where
such Notes may be surrendered for registration of transfer or for exchange and where notices and demands to or upon the Issuer in respect of such Notes and this Indenture may be served. The Issuer will give prompt written notice to the Trustee of
the location, and any change in the location, of such office or agency. If at any time the Issuer shall fail to maintain any such required office or agency or shall fail to furnish the Trustee with the address thereof, such presentations,
surrenders, notices and demands may be made or served at the Corporate Trust Office of the Trustee, and the Issuer hereby appoints the Trustee as its agent to receive all such presentations, surrenders, notices and demands. 

The Issuer may also from time to time designate one or more other offices or agencies where the Notes may be presented or surrendered for any
or all such purposes and may from time to time rescind such designations. The Issuer will give prompt written notice to the Trustee of any such designation or rescission and of any change in the location of any such other office or agency. 

The Issuer hereby designates the Corporate Trust Office of the Trustee as one such office or agency of the Issuer in accordance with
Section 2.03. 
 SECTION 4.03 Corporate Existence. 

Except as otherwise permitted by Article Five and the other provisions of this Indenture, the Issuer shall do or cause to be done all things
necessary to preserve and keep in full force and effect its corporate existence and the corporate, partnership, limited liability company or other existence of each of its Restricted Subsidiaries in accordance with the respective organizational
documents (as the same may be amended from time to time) of each such Restricted 
 Subsidiary and the material rights (charter and
statutory) and material franchises of the Issuer and each of its Restricted Subsidiaries; provided, however, that the Issuer shall not be required to preserve any such right or franchise with respect to itself or any Restricted
Subsidiary or any such corporate, partnership, limited liability company or other existence with respect to any Restricted Subsidiary if the Issuer shall determine that the preservation thereof is no longer desirable in the conduct of the business
of the Issuer and its Restricted Subsidiaries, taken as a whole. 
 SECTION 4.04 Compliance Certificate. 

(a) The Issuer and each Guarantor (to the extent that such Guarantor is so required under the Trust Indenture Act) shall deliver to the
Trustee, within one hundred twenty (120) days after the close of each fiscal year, an Officers’ Certificate, one of the signatories of which shall 

  
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be the Issuer’s or Guarantor’s, as applicable, principal executive officer, principal financial officer or principal accounting officer (as such terms are defined in the Trust Indenture
Act), stating that a review of the activities of the Issuer or Guarantor, as applicable, has been made under the supervision of the signing officers with a view to determining whether it has kept, observed, performed and fulfilled its obligations
under this Indenture and further stating, as to each such Officer signing such certificate, that to such Officer’s knowledge, the Issuer or Guarantor, as applicable, during such preceding fiscal year has kept, observed, performed and fulfilled
each and every such covenant and no Default occurred during such year and at the date of such certificate there is no Default that has occurred and is continuing or, if such signers do know of such Default, the certificate shall describe its status
with particularity. 
 (b) Upon any Officer of the Issuer becoming aware of any Default, the Issuer shall deliver to the Trustee an
Officers’ Certificate specifying such Default and what action the Issuer is taking or proposes to take with respect thereto. 
 (c) The
Officers’ Certificate shall also notify the Trustee should the Issuer elect to change the manner in which it fixes its fiscal year end. 

  
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 SECTION 4.05 Waiver of Stay, Extension or Usury Laws. 

The Issuer and each Guarantor covenants (to the extent permitted by applicable law) that it will not at any time insist upon, plead, or in any
manner whatsoever claim or take the benefit or advantage of, any stay or extension law or any usury law or other law that would prohibit or forgive such Issuer or such Guarantor from paying all or any portion of the principal of or interest on the
Notes or the Guarantee of any such Guarantor as contemplated herein, wherever enacted, now or at any time hereafter in force, or which may affect the covenants or the performance of this Indenture, and (to the extent permitted by applicable law)
each hereby expressly waives all benefit or advantage of any such law, and covenants that it will not hinder, delay or impede the execution of any power herein granted to the Trustee, but will suffer and permit the execution of every such power as
though no such law had been enacted. 
 SECTION 4.06 Change of Control. 

(a) Upon the occurrence of any Change of Control, each Holder of Notes will have the right to require the Issuer to repurchase all or any part
(equal to $1,000 or an integral multiple thereof; provided, however, that no Note shall be repurchased in part if such Note would have a remaining principal amount of less than $2,000) of that Holder’s Notes pursuant to a Change
of Control Offer (the “Change of Control Offer”). In the Change of Control Offer, the Issuer will offer to pay an amount in cash (the “Change of Control Purchase Price”) equal to 101% of the aggregate principal
amount of Notes purchased, plus accrued and unpaid interest thereon, if any, to but excluding the date of purchase. Within thirty (30) days following any Change of Control, the Issuer will mail, or cause to be mailed, a notice to each
Holder describing the transaction or transactions that constitute the Change of Control and offering to purchase Notes on the date (the “Change of Control Payment Date”) specified in such notice, which date shall be a Business Day
no earlier than thirty (30) days and no later than sixty (60) days from the date such notice is mailed, pursuant to the procedures described below. Such notice shall state: 

(1) that the Change of Control Offer is being made pursuant to this Section 4.06 and that all Notes tendered and not
withdrawn will be accepted for payment; 
 (2) the Change of Control Purchase Price and the Change of Control Payment Date;

 (3) that any Note not tendered will continue to accrue interest; 

(4) that, unless the Issuer defaults in making payment therefor, any Note accepted for payment pursuant to the Change of
Control Offer shall cease to accrue interest after the Change of Control Payment Date; 
 (5) that Holders electing to have a
Note purchased pursuant to a Change of Control Offer will be required to surrender the Note, with the form entitled “Option of Holder to Elect Purchase” on the reverse of the Note completed, to the Paying Agent at the address specified in
the notice prior to the close of business on the third (3rd) Business Day prior to the Change of Control Payment Date; 

  
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 (6) that Holders will be entitled to withdraw their election if the Paying Agent
receives, not later than the second (2nd) Business Day prior to the Change of Control Payment Date, a telegram, facsimile transmission or letter setting forth the name of the Holder, the principal amount of the Notes the Holder delivered for
purchase and a statement that such Holder is withdrawing his election to have such Note purchased; 
 (7) that Holders whose
Notes are purchased only in part will be issued new Notes in a principal amount equal to the unpurchased portion of the Notes surrendered (equal to integral multiple of $1,000 but not less than $2,000); and 

(8) the circumstances and relevant facts regarding such Change of Control. 

(b) On or before the Change of Control Payment Date, the Issuer will, to the extent lawful: 

(1) accept for payment all Notes or portions thereof properly tendered pursuant to the Change of Control Offer; 

(2) deposit with the Paying Agent funds sufficient to pay the Change of Control Purchase Price in respect of all Notes or
portions thereof so tendered; and 
 (3) deliver or cause to be delivered to the Trustee the Notes so accepted together with
an Officers’ Certificate stating the aggregate principal amount of Notes or portions thereof being purchased by the Issuer. 
 (c) The
Paying Agent will promptly mail to each Holder of Notes so tendered the Change of Control Purchase Price for such Notes, and the Trustee will promptly authenticate and mail (or cause to be transferred by book entry) to each Holder a new Note equal
in principal amount to any unpurchased portion of the Notes surrendered, if any; provided, however, that each such new Note will be in a principal amount equal to an integral multiple of $1,000 but not less than $2,000. 

(d) The Issuer will publicly announce the results of the Change of Control Offer on or as soon as practicable after the Change of Control
Payment Date. 
 (e) The Issuer will not be required to make a Change of Control Offer upon a Change of Control if (1) a third party
makes the Change of Control Offer in the manner, at the times and otherwise in compliance with the requirements set forth in this Indenture applicable to a Change of Control Offer made by the Issuer and purchases all Notes validly tendered and not
withdrawn under such Change of Control Offer, or (2) notice of redemption has been given to the Trustee pursuant to the Indenture with respect to all of the Notes then outstanding as described under Section 5 or Section 7 of the
Notes, unless and until there is a default in payment of the applicable redemption price. Notwithstanding anything to the contrary contained herein, a Change of Control Offer may be made in advance of a Change of Control, or conditioned upon the
consummation of such Change of Control, if a definitive agreement is in place for the Change of Control at the time the Change of Control Offer is made. 

  
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 (f) The Issuer shall cause the Change of Control Offer to remain open for at least twenty
(20) Business Days or for such longer period as may be required by law. The Issuer will comply, and will cause any third party making a Change of Control Offer to comply, with the requirements of Rule 14e-1 under the Exchange Act and any other
securities laws and regulations thereunder to the extent such laws and regulations are applicable in connection with a Change of Control Offer. To the extent the provisions of any applicable securities laws or regulations conflict with the
provisions of this Section 4.06, the Issuer will not be deemed to have breached its obligations under this Section 4.06 by virtue of complying with such laws or regulations. 

(g) In the event that at the time of such Change of Control the terms of the Indebtedness under any Credit Agreement restrict or prohibit the
purchase of the Notes pursuant to this Section 4.06, then prior to the mailing of the notice to Holders provided for in Section 4.06(a), but in any event within thirty (30) days following any Change of Control, the Issuer shall
(i) repay in full the Indebtedness and terminate all commitments under such Credit Agreement or (ii) obtain the requisite consent under the agreements governing the Indebtedness under such Credit Agreement to permit the purchase of the
Notes as provided for in this Section 4.06. 
 (h) The Issuer shall first comply with the covenant in the immediately preceding
sentence before it shall be required to repurchase Notes or send the notice to the Holders referred to in clause (a) above pursuant to the provisions of this Section 4.06. The Issuer’s failure to comply with the covenant described in
the second preceding sentence (and any failure to send the notice referred to in clause (a) above because the same is prohibited by the second preceding sentence) may (with notice and lapse of time) constitute an Event of Default described in
Section 6.01(3) but shall not constitute an Event of Default described in Section 6.01(2). 
 (i) In the event that Holders of not
less than 90% in aggregate principal amount of the then outstanding Notes accept a Change of Control Offer and the Issuer (or any third party making such Change of Control Offer in lieu of the Issuer as described in Section 4.06(e)(1) above)
purchases all of the Notes held by such Holders, the Issuer will have the right, upon not less than 30 nor more than 60 days’ prior notice, given not more than 30 days following the purchase pursuant to the Change of Control Offer described
above, to redeem all of the Notes that remain outstanding following such purchase at a redemption price equal to the Change of Control Purchase Price plus accrued and unpaid interest on the Notes that remain outstanding, to the date of redemption,
subject to the rights of Holders of the Notes on the relevant regular record date to receive interest due on the relevant interest payment date that is on or prior to the applicable redemption date. 

SECTION 4.07 Limitations on Additional Indebtedness. 

(a) The Issuer will not, and will not permit any Restricted Subsidiary to, directly or indirectly, incur any Indebtedness; provided,
however, that the Issuer or any Restricted Subsidiary may incur additional Indebtedness, and the Issuer or any Restricted Subsidiary may incur Acquired Indebtedness if, after giving effect thereto, the Consolidated Interest Coverage Ratio would
be at least 2.00 to 1.00 (the “Coverage Ratio Exception”). 

  
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 (b) Notwithstanding Section 4.07(a), each of the following shall be permitted to be incurred
(the “Permitted Indebtedness”): 
 (1) Indebtedness of the Issuer or any Restricted Subsidiary under any
Credit Facility (including any Credit Agreement) (including the issuance or creation of letters of credit or bankers’ acceptances thereunder) so long as the aggregate amount of all Indebtedness of the Issuer and its Restricted Subsidiaries
(without duplication) at any time outstanding under all Credit Facilities (including all Credit Agreements) (excluding Hedging Obligations related to the Indebtedness thereunder) does not exceed the greatest of (x) $2,350.0 million, less
the aggregate amount of Net Available Proceeds applied after the Issue Date to repayments under any Credit Facility (including any Credit Agreement) pursuant to Section 4.10(c), (y) the maximum aggregate principal amount of
Indebtedness that would not result in the Consolidated Secured Leverage Ratio, after giving effect to the incurrence of such Indebtedness and the application of the proceeds therefrom, being greater than 4.75 to 1.00, less the aggregate
amount of Net Available Proceeds applied after the Issue Date to repayments under any Credit Facility (including any Credit Agreement) pursuant to Section 4.10(c), and (z) 85% of the book value of the accounts receivable of the Issuer and
the Restricted Subsidiaries plus 65% of the book value of inventory of the Issuer and the Restricted Subsidiaries, in each case calculated on a consolidated basis and in accordance with GAAP as of the last day of the last full fiscal quarter
for which financial statements are available; 
 (2) the Initial Notes and the related Guarantees; 

(3) Indebtedness of the Issuer and the Restricted Subsidiaries to the extent outstanding on the Issue Date (other than
Indebtedness referred to in clauses (1) and (2) above); 
 (4) Indebtedness of the Issuer or any Restricted
Subsidiary under Hedging Obligations (i) entered into for bona fide purposes of hedging against fluctuations in interest rates with respect to Indebtedness under any Credit Facility (including any Credit Agreement) or (ii) entered
into in the ordinary course of business for bona fide hedging purposes and not for the purpose of speculation that are designed to protect against fluctuations in interest rates, foreign currency exchange rates and commodity prices,
provided that if, in the case of either (i) or (ii), such Hedging Obligations are of the type described in clause (1) of the definition thereof, (a) such Hedging Obligations relate to payment obligations on Indebtedness
otherwise permitted to be incurred by this covenant and (b) the notional principal amount of such Hedging Obligations at the time incurred does not exceed the principal amount of the Indebtedness to which such Hedging Obligations relate; 

(5) Indebtedness of the Issuer owed to a Restricted Subsidiary and Indebtedness of any Restricted Subsidiary owed to the Issuer
or any other Restricted Subsidiary, provided that upon any such Restricted Subsidiary ceasing to be a Restricted Subsidiary or such Indebtedness being owed to any Person other than the Issuer or a Restricted Subsidiary, the Issuer or such
Restricted Subsidiary, as applicable, shall be deemed to have incurred Indebtedness not permitted by this clause (5); 

  
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 (6) (i) Indebtedness in respect of bid, performance or surety bonds issued for
the account of the Issuer or any Restricted Subsidiary in the ordinary course of business, including guarantees or obligations of the Issuer or any Restricted Subsidiary with respect to letters of credit supporting such bid, performance or surety
obligations (in each case other than for an obligation for money borrowed), and (ii) Indebtedness of the Issuer or any Restricted Subsidiary consisting of reimbursement obligations with respect to commercial letters of credit, letters of credit
issued to landlords and other letters of credit, in each case in the ordinary course of business in an aggregate face amount not to exceed $26.25 million at any time; 

(7) Purchase Money Indebtedness incurred by the Issuer or any Restricted Subsidiary, and Refinancing Indebtedness with respect
thereto, in an aggregate outstanding amount not to exceed $50.0 million at any time; 
 (8) Indebtedness of the Issuer or any
Restricted Subsidiary arising from the honoring by a bank or other financial institution of a check, draft or similar instrument inadvertently (except in the case of daylight overdrafts) drawn against insufficient funds in the ordinary course of
business, provided that such Indebtedness is extinguished within five (5) Business Days of incurrence; 
 (9)
Indebtedness of the Issuer or any Restricted Subsidiary arising in connection with endorsement of instruments for deposit in the ordinary course of business; 

(10) (i) Capitalized Lease Obligations arising under Sale and Leaseback Transactions with respect to any of the real property
currently owned by Alere San Diego, Inc. or any of its Restricted Subsidiaries in San Diego, California, and Refinancing Indebtedness with respect thereto, in an aggregate outstanding amount for all such transactions under this clause (i) not
to exceed $200.0 million at any time and (ii) Capitalized Lease Obligations arising under any other Sale and Leaseback Transactions, and Refinancing Indebtedness with respect thereto, in an aggregate outstanding amount for all such
transactions under this clause (ii) not to exceed $50.0 million at any time; 
 (11) guarantee Obligations of the Issuer
or any of its Restricted Subsidiaries with respect to Indebtedness of the Issuer or any of its Restricted Subsidiaries; 

(12) (i) Indebtedness incurred by the Issuer or any Restricted Subsidiary for the purpose of financing all or any part of the
cost of, or in order to consummate, the acquisition of (x) Equity Interests of another Person engaged in the Permitted Business that becomes a Restricted Subsidiary, (y) all or substantially all of the assets of such a Person or a line of
business, division or business unit within the Permitted Business by the Issuer or a Restricted Subsidiary, or (z) any other Permitted Business assets by the Issuer or a Restricted Subsidiary and (ii) Acquired Indebtedness incurred by the
Issuer or any Restricted Subsidiary in connection with an acquisition by the Issuer or a Restricted Subsidiary; provided, however, that, in each of the foregoing cases, on the date of the incurrence of such Indebtedness or Acquired
Indebtedness, after giving effect to the incurrence thereof and the use of any proceeds therefrom and otherwise determined on a 

  
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pro forma basis for such transaction in accordance with the provisions set forth in the definition of “Consolidated Interest Coverage Ratio,” either: 

(A) the Issuer would be permitted to incur at least $1.00 of additional Indebtedness pursuant to the Coverage Ratio Exception,
or 
 (B) the Consolidated Interest Coverage Ratio would be greater than the Consolidated Interest Coverage Ratio immediately
prior to the incurrence of such Indebtedness; 
 (13) guarantees by the Issuer or any of its Restricted Subsidiaries of the
performance by any Restricted Subsidiary of its obligations under the P&G JV Agreements or the joint venture agreement or other related agreements, instruments or documents relating to any other joint venture entered into by the Issuer of any of
its Restricted Subsidiaries in compliance with this Indenture (for the avoidance of doubt this clause shall not be read to allow guarantees of Indebtedness of any joint venture or joint venture partner or their Affiliates); 

(14) Refinancing Indebtedness incurred by the Issuer or any Restricted Subsidiary with respect to Indebtedness
incurred pursuant to the Coverage Ratio Exception or clause (2), (3) or (12) or this clause (14) in this Section 4.07(b); 

(15) Indebtedness of any Foreign Subsidiary or of any Domestic Subsidiary that is not a Guarantor in an aggregate outstanding
principal amount for all such Indebtedness at any time not to exceed $50.0 million; and 
 (16) any other Indebtedness of the
Issuer or any Restricted Subsidiary in an aggregate outstanding principal amount for all such Indebtedness not to exceed $50.0 million at any time. 

(c) For purposes of determining compliance with this Section 4.07, in the event that an item of Indebtedness meets the criteria of more
than one of the categories of Permitted Indebtedness described in clauses (1) through (16) of Section 4.07(b) or is entitled to be incurred pursuant to the Coverage Ratio Exception, the Issuer shall, in its sole discretion, classify
such item of Indebtedness and may divide and classify (and may later redivide and reclassify) such Indebtedness in more than one of the types of Indebtedness described in Section 4.07(a) or Section 4.07(b) in any manner that complies with
this Section 4.07, except that Indebtedness incurred under the Credit Agreement on the Issue Date shall be deemed to have been incurred under clause (1) of Section 4.07(b). Any item of Indebtedness entitled to be incurred pursuant to
the Coverage Ratio Exception and classified by the Issuer within such type of Indebtedness shall retain such classification (and the amount thereof shall not be counted in the determination of the amount of Indebtedness under any of clauses
(1) through (16) of Section 4.07(b)) notwithstanding that the Coverage Ratio Exception is not available at any later time. In addition, for purposes of determining any particular amount of Indebtedness under this Section 4.07 or
any category of Permitted Indebtedness, guarantees, Liens, letter of credit obligations or other obligations supporting Indebtedness otherwise included in the determination of such particular amount shall not be included so long as incurred by a
Person that could have incurred such Indebtedness. 

  
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 (d) The accrual of interest, the accretion or amortization of original issue discount, the
payment of interest on any Indebtedness in the form of additional Indebtedness with the same terms and the payment of dividends on Disqualified Equity Interests of the Issuer in the form of additional shares of the same class of Disqualified Equity
Interest (or in the form of Qualified Equity Interests) will not be deemed to be an incurrence of Indebtedness for purposes of this Section 4.07. 

SECTION 4.08 Limitations on Restricted Payments. 

(a) The Issuer will not, and will not permit any Restricted Subsidiary to, directly or indirectly, make any Restricted Payment if at the time
of such Restricted Payment: 
 (1) a Default shall have occurred and be continuing or shall occur as a consequence thereof;

 (2) the Issuer cannot incur $1.00 of additional Indebtedness pursuant to the Coverage Ratio Exception; or 

(3) the amount of such Restricted Payment, when added to the aggregate amount of all other Restricted Payments made after the
Issue Date (other than Restricted Payments made pursuant to clauses (2) through (7), (8) (with respect to non-cash dividends only), (10), (11) and (12) of Section 4.08(b), exceeds the sum (the “Restricted Payments
Basket”) of (without duplication): 
 (i) 50% of Consolidated Net Income for the period (taken as one accounting
period) commencing on the first (1st) day of the fiscal quarter in which the Issue Date occurs to and including the last day of the fiscal quarter ended immediately prior to the date of such
calculation for which consolidated financial statements are available (or, if such Consolidated Net Income shall be a deficit, minus 100% of such aggregate deficit), plus 

(ii) 100% of the aggregate net proceeds, including cash and the Fair Market Value of the equity of a Person or of assets used
in or constituting a line of business, in each case which becomes or becomes owned by a Restricted Subsidiary, received by the Issuer from the issuance and sale of Qualified Equity Interests after the Issue Date, other than any such proceeds which
are used to redeem Notes in accordance with Section 6 of the Notes, provided that the Issuer delivers to the Trustee: 

(x) with respect to any equity or assets with a Fair Market Value in excess of $15.0 million, an Officers’ Certificate
setting forth such Fair Market Value and a Secretary’s Certificate which sets forth and authenticates a resolution that has been adopted by a majority of the Independent Directors approving such Fair Market Value; and 

  
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 (y) with respect to any equity or assets with a Fair Market Value in excess of
$50.0 million, the certificates described in the preceding clause (x) and a written opinion as to the Fair Market Value of such equity or assets received by the Issuer from the issuance and sale of such Qualified Equity Interests issued by an
Independent Financial Advisor (which opinion may be in the form of a fairness opinion with respect to the transaction in which the equity or assets are acquired), plus 

(iii) 100% of the aggregate net cash proceeds received by the Issuer as contributions to the common or preferred equity (other
than Disqualified Equity Interests) of the Issuer after the Issue Date, other than any such proceeds which are used to redeem Notes in accordance with Section 6 of the Notes, plus 

(iv) the aggregate amount by which Indebtedness incurred by the Issuer or any Restricted Subsidiary subsequent to the Issue
Date is reduced on the Issuer’s balance sheet upon the conversion or exchange (other than by a Subsidiary of the Issuer) of Indebtedness into Qualified Equity Interests (less the amount of any cash, or the fair value of assets,
distributed by the Issuer or any Restricted Subsidiary upon such conversion or exchange), plus 
 (v) in the case of
the disposition or repayment of or return on any Investment that was treated as a Restricted Payment made after the Issue Date, an amount (to the extent not included in the computation of Consolidated Net Income) equal to the lesser of (A) the
return of capital with respect to such Investment and (B) the amount of such Investment that was treated as a Restricted Payment, in either case, less the cost of the disposition of such Investment and net of taxes, plus 

(vi) upon a Redesignation of an Unrestricted Subsidiary as a Restricted Subsidiary, the lesser of (A) the Fair Market
Value of the Issuer’s proportionate interest in such Subsidiary immediately following such Redesignation, and (B) the aggregate amount of the Issuer’s Investments in such Subsidiary to the extent such Investments reduced the
Restricted Payments Basket and were not previously repaid or otherwise reduced. 
 (b) The foregoing provisions shall not prohibit: 

(1) the payment by the Issuer or any Restricted Subsidiary of any dividend within sixty (60) days after the date of
declaration thereof, if on the date of declaration the payment would have complied with the provisions of this Indenture; 

(2) the redemption of any Equity Interests of the Issuer or any Restricted Subsidiary in exchange for, or out of the proceeds
of the substantially concurrent issuance and sale of, Qualified Equity Interests (and any payment of cash in lieu of delivering fractional shares in connection therewith); 

(3) the redemption of Subordinated Indebtedness of the Issuer or any Restricted Subsidiary (i) in exchange for, or out of
the proceeds of the substantially 

  
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concurrent issuance and sale of, Qualified Equity Interests (and any payment of cash in lieu of delivering fractional shares in connection therewith) or (ii) in exchange for, or out of the
proceeds of the substantially concurrent incurrence of, Refinancing Indebtedness permitted to be incurred under Section 4.07 and the other terms of this Indenture; 

(4) the redemption of Equity Interests of the Issuer held by officers, directors or employees or former officers, directors or
employees (or their transferees, estates or beneficiaries under their estates) upon their death, disability, retirement, severance or termination of employment or service; provided, however, that the aggregate cash consideration paid
for all such redemptions shall not exceed $15.0 million during any calendar year, with any portion of such amount that is not used during such calendar year being carried forward to the succeeding calendar year, subject to a maximum of $20.0 million
during any calendar year; 
 (5) repurchases of Equity Interests deemed to occur upon the exercise of stock options or
warrants if the Equity Interests represents a portion of the exercise price thereof; 
 (6) the redemption of any
Indebtedness of the Issuer or any Restricted Subsidiary owing to any Restricted Subsidiary or the Issuer; 
 (7) upon the
occurrence of a Change of Control and within one hundred twenty (120) days after the completion of the offer to repurchase the Notes pursuant to Section 4.06, any redemption of Indebtedness of the Issuer required pursuant to the terms
thereof; 
 (8) the payment by the Issuer of cash dividends on shares of its common stock or preferred stock to the holders
thereof; provided, however, that the aggregate amount of all cash dividends paid pursuant to this clause (8) shall not exceed $25.0 million during any calendar year; 

(9) payments of dividends on Disqualified Equity Interests issued in compliance with Section 4.07; 

(10) payments made using any Net Proceeds Deficiency; 

(11) redemptions and repurchases of Equity Interests of the Issuer held by any Person; provided, however, that
the aggregate cash consideration paid for all such redemptions and repurchases made pursuant to this clause (11) shall not exceed $200.0 million in the aggregate; or 

(12) other Restricted Payments in an amount which, when taken together with all other Restricted Payments made pursuant to this
clause (12), does not exceed $215.0 million in the aggregate (with the amount of each Restricted Payment being determined as of the date made and without regard to subsequent changes in value); 

provided, however, that (x) in the case of any Restricted Payment pursuant to clause (3)(ii), (10) or (12) of this
Section 4.08(b), no Default shall have occurred and be continuing or will occur as 

  
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a consequence thereof and (y) no issuance and sale of Qualified Equity Interests pursuant to clause (2) or (3) of this Section 4.08(b) shall increase the Restricted Payments
Basket, except to the extent the proceeds thereof exceed the amounts used to effect the transactions described therein. 
 SECTION 4.09 Limitations
on Liens. 
 The Issuer shall not, and shall not permit any Restricted Subsidiary to, directly or indirectly, create, incur, assume or
permit or suffer to exist any Lien of any nature whatsoever (other than Permitted Liens) against any assets of the Issuer or any Restricted Subsidiary (including Equity Interests of a Restricted Subsidiary), whether owned on the Issue Date or
thereafter acquired, or any proceeds therefrom, in each case securing an obligation that ranks pari passu in right of payment with, or that is subordinated in right of payment to, the Notes or any Guarantee, unless contemporaneously
therewith: 
 (a) in the case of any Lien securing an obligation that ranks pari passu in right of payment with the Notes or any
Guarantee, effective provision is made to secure the Notes or such Guarantee, as the case may be, at least equally and ratably with or prior to such obligation with a Lien on the same collateral; and 

(b) in the case of any Lien securing an obligation that is subordinated in right of payment to the Notes or a Guarantee, effective provision
is made to secure the Notes or such Guarantee, as the case may be, with a Lien on the same collateral that is prior to the Lien securing such subordinated obligation, 

in each case, for so long as such obligation is secured by such Lien. 

SECTION 4.10 Limitations on Asset Sales. 

(a) The Issuer will not, and will not permit any Restricted Subsidiary to, directly or indirectly, consummate any Asset Sale unless: 

(1) the Issuer or such Restricted Subsidiary receives consideration at the time of such Asset Sale at least equal to the Fair
Market Value of the assets included in such Asset Sale; and 
 (2) at least 75% of the total consideration received in such
Asset Sale consists of cash or Cash Equivalents. 
 For purposes of clause (2) (and not for purposes of determining the Net Available
Proceeds with respect to the application and purchase offer provisions in this Section 4.10), the following shall be deemed to be cash: 

(i) the amount (without duplication) of any Indebtedness of the Issuer or such Restricted Subsidiary that is expressly assumed
by the transferee in such Asset Sale and with respect to which the Issuer or such Restricted Subsidiary, as the case may be, is released by the holder of such Indebtedness; 

  
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 (ii) the amount of any obligations received from such transferee that are within
one hundred eighty (180) days converted by the Issuer or such Restricted Subsidiary to cash (to the extent of the cash actually so received); 

(iii) the Fair Market Value of (x) any assets (other than securities) received by the Issuer or any Restricted Subsidiary
to be used by it in the Permitted Business, (y) Equity Interests in a Person that is a Restricted Subsidiary or in a Person engaged in a Permitted Business that shall become a Restricted Subsidiary immediately upon the acquisition of such
Person by the Issuer or (z) a combination of (x) and (y); and 
 (iv) the Fair Market Value of any Equity Interests
for which the Issuer or such Restricted Subsidiary has a contractual right to require the registration (or equivalent) of such Equity Interests under the Securities Act or the applicable securities laws of the jurisdiction in which such securities
are listed on a Major Foreign Exchange (“Designated Non-Cash Consideration”); provided, however, that no consideration received in an Asset Sale will constitute Designated Non-Cash Consideration if and to the extent
that the classification of such consideration as Designated Non-Cash Consideration would cause the aggregate amount of all such Designated Non-Cash Consideration outstanding at that time to exceed 2.5% of Consolidated Total Assets (with the Fair
Market Value of each item of Designated Non-Cash Consideration being measured at the time received and without giving effect to subsequent changes in value). 

(b) If at any time any non-cash consideration (including any Designated Non-Cash Consideration) received by the Issuer or any Restricted
Subsidiary of the Issuer, as the case may be, in connection with any Asset Sale is repaid or converted into or sold or otherwise disposed of for cash (other than interest received with respect to any such non-cash consideration), then the date of
such repayment, conversion or disposition shall be deemed to constitute the date of an Asset Sale hereunder and the Net Available Proceeds thereof shall be applied in accordance with this Section 4.10. 

(c) If the Issuer or any Restricted Subsidiary engages in an Asset Sale, the Issuer or such Restricted Subsidiary shall, no later than 360
days following the consummation thereof, apply all or any (or, in the Issuer’s discretion, none) of the Net Available Proceeds therefrom to: 

(1) repay Senior Debt or Guarantor Senior Debt, and in the case of any such repayment under any revolving credit facility,
effect a permanent reduction in the availability under such revolving credit facility, in each case if and to the extent permitted under the terms of such Senior Debt or Guarantor Senior Debt; 

(2) repay any Indebtedness which was secured by the assets sold in such Asset Sale; or 

(3) (i) invest all or any part of the Net Available Proceeds thereof in assets (other than securities), including expenditures
for research and development activities, to be used by the Issuer or any Restricted Subsidiary in the Permitted Business, (ii) acquire 

  
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Equity Interests in a Person that is a Restricted Subsidiary or in a Person engaged in a Permitted Business that shall become a Restricted Subsidiary immediately upon the consummation of such
acquisition or (iii) a combination of (i) and (ii). 
 The amount of Net Available Proceeds not applied or invested as provided in this paragraph
will constitute “Excess Proceeds.” The Issuer or such Restricted Subsidiary may repay Senior Debt or Guarantor Senior Debt under a revolving Credit Facility during the 360 days following the consummation of such Asset Sale without
effecting a permanent reduction in the availability under such revolving credit facility, pending application of such proceeds pursuant to clause (1), (2) or (3) of this Section 4.10(c) or their use as Excess Proceeds in accordance
with the next paragraph, and such repayment shall not be considered an application of Net Available Proceeds for purposes of this paragraph; provided, however, that, if such Net Available Proceeds are not applied after 360 days for any
purpose other than the repayment of a revolving credit facility, a permanent reduction in the availability under such revolving credit facility shall then be required in order for such repayment to be considered an application of Net Available
Proceeds for purposes of this paragraph. 
 (d) When the aggregate amount of Excess Proceeds equals or exceeds $50.0 million, the Issuer
will be required to make an offer to purchase from all Holders and, if applicable, redeem (or make an offer to do so) any Pari Passu Indebtedness of the Issuer the provisions of which require the Issuer to redeem such Pari Passu Indebtedness with
the proceeds from any Asset Sales (or offer to do so), in an aggregate principal amount of Notes and such Pari Passu Indebtedness equal to the amount of such Excess Proceeds as follows: 

(1) the Issuer will (i) make an offer to purchase (a “Net Proceeds Offer”) to all Holders in accordance
with the procedures set forth in this Indenture, and (ii) redeem (or make an offer to do so) any such other Pari Passu Indebtedness, on a pro rata basis (or on as nearly a pro rata basis as is practicable) in proportion to the
respective principal amounts of the Notes and such other Pari Passu Indebtedness required to be redeemed, the maximum principal amount of Notes (in each case in whole in a principal amount of $1,000 or integral multiples thereof; provided,
however, that no Note will be purchased in part if such Note would have a remaining principal amount of less than $2,000) and Pari Passu Indebtedness that may be redeemed out of the amount (the “Payment Amount”) of such Excess
Proceeds; 
 (2) the offer price for the Notes will be payable in cash in an amount equal to 100% of the principal amount of
the Notes tendered pursuant to a Net Proceeds Offer, plus accrued and unpaid interest thereon, if any, to the date such Net Proceeds Offer is consummated (the “Offered Price”), in accordance with the procedures set forth in
this Indenture, and the redemption price for such Pari Passu Indebtedness (the “Pari Passu Indebtedness Price”) shall be as set forth in the related documentation governing such Indebtedness; 

(3) if the aggregate Offered Price of Notes validly tendered and not withdrawn by Holders thereof exceeds the pro rata
portion of the Payment Amount allocable to the Notes, Notes to be purchased will be selected on a pro rata basis (or on as nearly a pro rata basis as is practicable); and 

  
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 (4) upon completion of such Net Proceeds Offer in accordance with the foregoing
provisions, the amount of Excess Proceeds with respect to which such Net Proceeds Offer was made shall be deemed to be zero. 
 (e) To the
extent that the sum of the aggregate Offered Price of Notes tendered pursuant to a Net Proceeds Offer and the aggregate Pari Passu Indebtedness Price paid to the holders of such Pari Passu Indebtedness is less than the Payment Amount relating
thereto (such shortfall constituting a “Net Proceeds Deficiency”), the Issuer may use the Net Proceeds Deficiency, or a portion thereof, for general corporate purposes, subject to the provisions of this Indenture, and the amount of
Excess Proceeds with respect to such Net Proceeds Offer shall be deemed to be zero. 
 (f) Upon the commencement of a Net Proceeds Offer,
the Issuer shall send or cause to be sent, by first class mail, a notice to the Trustee and to each Holder at its registered address. The notice shall contain all instructions and materials necessary to enable such Holder to tender Notes pursuant to
the Net Proceeds Offer. Any Net Proceeds Offer shall be made to all Holders. The notice, which shall govern the terms of the Net Proceeds Offer, shall state: 

(1) that the Net Proceeds Offer is being made pursuant to this Section 4.10; 

(2) the Payment Amount, the Offered Price, and the date on which Notes tendered and accepted for payment shall be purchased,
which date shall be at least thirty (30) days and not later than sixty (60) days from the date such notices is mailed (the “Net Proceeds Payment Date”); 

(3) that any Notes not tendered or accepted for payment shall continue to accrue interest; 

(4) that, unless the Issuer defaults in making such payment, any Notes accepted for payment pursuant to the Net Proceeds Offer
shall cease to accrue interest on and after the Net Proceeds Payment Date; 
 (5) that Holders electing to have any Notes
purchased pursuant to any Net Proceeds Offer shall be required to surrender the Notes, with the form entitled “Option of Holder to Elect Purchase” on the reverse of the Note completed, or transfer by book-entry transfer, to the Issuer, a
depository, if appointed by the Issuer, or the Paying Agent at the address specified in the notice at least three (3) days before the Net Proceeds Payment Date; 

(6) that Holders shall be entitled to withdraw their election if the Issuer, the Depository or the Paying Agent, as the case
may be, receives, not later than the Net Proceeds Payment Date, a notice setting forth the name of the Holder, the principal amount of the Note the Holder delivered for purchase and a statement that such Holder is withdrawing his election to have
such Note purchased; 
 (7) that if the aggregate principal amount of Notes surrendered by Holders exceeds the Payment
Amount, the Issuer shall select the Notes to be purchased on a pro rata basis (with such adjustments as may be deemed appropriate by the Issuer so that 

  
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only Notes in denominations of $1,000, or integral multiples thereof, shall be purchased; provided, however, that no Note will be purchased in part if such Note would have a
remaining principal amount of less than $2,000); and 
 (8) that Holders whose Notes were purchased only in part shall be
issued new Notes equal in principal amount to the unpurchased portion of the Notes surrendered (or transferred by book-entry); provided, however, that each such new Note will be in a principal amount equal to an integral multiple of
$1,000 but not less than $2,000. 
 (g) On the Net Proceeds Payment Date, the Issuer shall, to the extent lawful: (1) accept for
payment all Notes or portions thereof properly tendered pursuant to the Net Proceeds Offer, subject to pro ration if the aggregate Notes tendered exceed the Payment Amount allocable to the Notes; (2) deposit with the Paying Agent funds in
Dollars equal to the lesser of the Payment Amount allocable to the Notes and the amount sufficient to pay the Offered Price in respect of all Notes or portions thereof so tendered; and (3) deliver or cause to be delivered to the Trustee the
Notes so accepted together with an Officers’ Certificate stating the aggregate principal amount of Notes or portions thereof being repurchased by the Issuer. The Issuer shall publicly announce the results of the Net Proceeds Offer on or as soon
as practicable after the Net Proceeds Payment Date. 
 (h) The Paying Agent shall promptly mail to each Holder of Notes so tendered the
Offered Price for such Notes, and the Trustee shall promptly authenticate pursuant to an Authentication Order and mail (or cause to be transferred by book-entry) to each Holder a new Note equal in principal amount to any unrepurchased portion of the
Notes surrendered, if any; provided, however, that each such new Note shall be in principal amount equal to an integral multiple of $1,000 but not less than $2,000. However, if the Net Proceeds Payment Date is on or after an interest
Record Date and on or before the related interest payment date, any accrued and unpaid interest shall be paid to the Person in whose name a Note is registered at the close of business on such Record Date, and no additional interest shall be payable
to Holders who tender Notes pursuant to the Net Proceeds Offer. 
 (i) The Issuer shall comply with applicable tender offer rules, including
the requirements of Rule 14e-1 under the Exchange Act and any other applicable laws and regulations in connection with the purchase of Notes pursuant to a Net Proceeds Offer. To the extent that the provisions of any securities laws or regulations
conflict with the provisions of this Section 4.10, the Issuer shall comply with the applicable securities laws and regulations and will not be deemed to have breached its obligations under this Section 4.10 by virtue of this compliance.

  
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 SECTION 4.11 Limitations on Transactions with Affiliates. 

(a) The Issuer will not, and will not permit any Restricted Subsidiary to, directly or indirectly, in one transaction or a series of related
transactions, sell, lease, transfer or otherwise dispose of any of its assets to, or purchase any assets from, or enter into any contract, agreement, understanding, loan, advance or guarantee with, or for the benefit of, any Affiliate (an
“Affiliate Transaction”), unless: 
 (1) such Affiliate Transaction is on terms that are no less favorable
to the Issuer or the relevant Restricted Subsidiary than those that would have been obtained in a comparable transaction at such time on an arm’s-length basis by the Issuer or that Restricted Subsidiary from a Person that is not an Affiliate of
the Issuer or that Restricted Subsidiary; and 
 (2) the Issuer delivers to the Trustee: 

(i) with respect to any Affiliate Transaction involving aggregate value expended by the Issuer or any Restricted Subsidiary in
a consecutive twelve-month period in excess of $15.0 million, an Officers’ Certificate certifying that such Affiliate Transaction complies with clause (1) above and a Secretary’s Certificate which sets forth and authenticates a
resolution that has been adopted by a majority of the Independent Directors approving such Affiliate Transaction; and 
 (ii)
with respect to any Affiliate Transaction involving aggregate value expended by the Issuer or any Restricted Subsidiary in a consecutive twelve-month period of $50.0 million or more, the certificates described in the preceding clause (i) and a
written opinion as to the fairness of such Affiliate Transaction to the Issuer or such Restricted Subsidiary from a financial point of view issued by an Independent Financial Advisor. 

(b) The foregoing restrictions shall not apply to: 

(1) transactions exclusively between or among (i) the Issuer and one or more Restricted Subsidiaries or
(ii) Restricted Subsidiaries, provided, in each case, that no Affiliate of the Issuer (other than another Restricted Subsidiary) owns Equity Interests of any such Restricted Subsidiary; 

(2) director, officer and employee compensation (including bonuses) and other benefits (including retirement, health, stock
option and other benefit plans) and indemnification and insurance arrangements; 
 (3) the entering into of any tax sharing
agreement, or the making of payments pursuant to any such agreement, between the Issuer or one or more Subsidiaries, on the one hand, and any other Person with which the Issuer or such Subsidiaries are required or permitted to file a consolidated
tax return or with which the Issuer or such Subsidiaries are part of a consolidated group for tax purposes, on the other hand, which payments by the Issuer and the Subsidiaries are not materially in excess of the tax liabilities that would have been
payable by them on a stand-alone basis; 

  
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 (4) any Permitted Investments; 

(5) Restricted Payments which are made in accordance with Section 4.08 (including payments and transactions that would
constitute Restricted Payments but for the exclusions in clauses (1) and (2) of the definition thereof); 
 (6) any
transaction with an Affiliate where the only consideration paid by the Issuer or any Restricted Subsidiary is Qualified Equity Interests (and any payments of cash in lieu of delivering fractional shares in connection therewith); 

(7) the sale to an Affiliate of the Issuer of Equity Interests of the Issuer that do not constitute Disqualified Equity
Interests, and the sale to an Affiliate of the Issuer of Indebtedness (including Disqualified Equity Interests) of the Issuer in connection with an offering of such Indebtedness in a market transaction and on terms substantially identical to those
of other purchasers in such market transaction who are not Affiliates; 
 (8) any transaction with a joint venture in which
the Issuer or a Restricted Subsidiary is a joint venturer and no other Affiliate is a joint venturer, or with any Subsidiary thereof or other joint venturer therein, pursuant to the joint venture agreement or related agreements for such joint
venture, including any transfers of any equity or ownership interests in any such joint venture to any other joint venturer therein pursuant to the performance or exercise of any rights or obligations to make such transfer under the terms of the
agreements governing such joint venture; or 
 (9) without limiting clause (8) immediately above, (i) any
transaction with a P&G JV Company or any Subsidiary or member thereof pursuant to the P&G JV Agreements or (ii) any other transactions with a P&G JV Company or any Subsidiary or member thereof for the manufacturing, packaging,
supply or distribution of products or materials, or the provision of other administrative or operational services (whether on a transitional or ongoing basis), solely with respect to the consumer diagnostic business, so long as, with respect to this
clause (ii), the charges for manufacturing such products are on a “cost-plus” basis. 
 The foregoing restrictions in
Section 4.11(a)(2) shall not apply to ordinary course transactions between the Issuer or any Restricted Subsidiary and an Unrestricted Subsidiary. 

SECTION 4.12 Limitations on Dividend and Other Restrictions Affecting Restricted Subsidiaries. 

The Issuer will not, and will not permit any Restricted Subsidiary to, directly or indirectly, create or otherwise cause or permit to exist or
become effective any consensual encumbrance or consensual restriction on the ability of any Restricted Subsidiary to: 
 (a) pay dividends
or make any other distributions on or in respect of its Equity Interests; 
 (b) make loans or advances, or pay any Indebtedness or other
obligation owed, to the Issuer or any other Restricted Subsidiary; or 

  
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 (c) transfer any of its assets to the Issuer or any other Restricted Subsidiary; 

except for: 
 (1) encumbrances or
restrictions existing under or by reason of applicable law; 
 (2) encumbrances or restrictions existing under the Indenture
(including the Guarantees) and the Notes; 
 (3) non-assignment provisions or other restrictions on transfer contained in any
lease, license or other contract; 
 (4) encumbrances or restrictions existing under agreements existing on the Issue Date
(including any Credit Facility (including the Credit Agreement), the Senior Notes Indenture and the Existing Senior Subordinated Notes Indentures) (with similar restrictions under any such agreement applicable to future Restricted Subsidiaries being
permitted hereunder); 
 (5) encumbrances or restrictions under any Credit Facility (including any Credit Agreement)
(including with regard to future Restricted Subsidiaries); 
 (6) restrictions on the transfer of assets subject to any Lien
imposed by the holder of such Lien; 
 (7) restrictions on the transfer of assets imposed under any agreement to sell such
assets to any Person pending the closing of such sale; 
 (8) encumbrances or restrictions under any instrument governing
Acquired Indebtedness that are not applicable to any Person, or the properties or assets of any Person, other than the Person or the properties or assets of the Person so acquired; 

(9) encumbrances or restrictions under any other agreement entered into after the Issue Date that are, in the good faith
judgment of the Issuer, not materially more restrictive, taken as a whole, with respect to any Restricted Subsidiary than those in effect on the Issue Date with respect to that Restricted Subsidiary (or any future Restricted Subsidiary) pursuant to
agreements in effect on the Issue Date (including the Indenture, the Senior Notes Indenture, the Existing Senior Subordinated Notes Indentures and the Credit Agreement); 

(10) restrictions under customary provisions in partnership agreements, limited liability company organizational or governance
documents, joint venture agreements, corporate charters, stockholders’ agreements, and other similar agreements and documents on the transfer of ownership interests in such partnership, limited liability company, joint venture or similar
Person; 

  
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 (11) encumbrances or restrictions imposed under Purchase Money Indebtedness on
the assets acquired that are of the nature described in clause (c) above, provided such Purchase Money Indebtedness is incurred in compliance with Section 4.07; 

(12) restrictions of the nature described in clause (c) above contained in any security agreement or mortgage securing
Indebtedness or other obligations of the Issuer or any Restricted Subsidiary to the extent such restrictions restrict the transfer of the property subject to such security agreement or mortgage; and 

(13) any encumbrances or restrictions imposed by any amendments or refinancings of the contracts, instruments or obligations
referred to in clauses (1) through (12) above; provided, however, that such encumbrances or restrictions are, in the good faith judgment of the Issuer, no more materially restrictive, taken as a whole, than those in effect
prior to such amendment or refinancing. 
 SECTION 4.13 Additional Guarantees. 

(a) If, after the Issue Date, (i) the Issuer or any Restricted Subsidiary acquires or creates a Domestic Subsidiary that guarantees any
Indebtedness or other Obligation under any Credit Agreement (other than a Subsidiary that has been designated an Unrestricted Subsidiary), (ii) any Unrestricted Subsidiary that is a Domestic Subsidiary that guarantees any Indebtedness or other
Obligation under any Credit Agreement is redesignated a Restricted Subsidiary, then, in each such case, the Issuer shall cause such Restricted Subsidiary to execute and deliver to the Trustee a supplemental indenture in the form of Exhibit E
attached to this Indenture, pursuant to which such Restricted Subsidiary shall unconditionally and irrevocably guarantee all of the Issuer’s obligations under the Notes and this Indenture. Thereafter, such Restricted Subsidiary shall be a
Guarantor for all purposes of this Indenture. 
 (b) Notwithstanding Section 4.13(a), a Subsidiary Guarantor will be automatically and
unconditionally released and discharged from its obligations under its Guarantee and this Indenture under the circumstances set forth in Section 11.04. 

SECTION 4.14 Limitation on Layering Indebtedness. 

(a) The Issuer will not, and will not permit any Restricted Subsidiary to, directly or indirectly, incur any Indebtedness that by its terms (or
by the terms of any agreement governing such Indebtedness) is or purports to be senior in right of payment to the Notes or the Guarantee, if any, of such Restricted Subsidiary and subordinated in right of payment to any other Indebtedness of the
Issuer or of such Restricted Subsidiary, as the case may be. 
 (b) For purposes of Section 4.14(a), no Indebtedness will be deemed to
be subordinated in right of payment to any other Indebtedness of the Issuer or any Restricted Subsidiary solely by virtue of being unsecured or by virtue of the fact that the holders of such Indebtedness have entered into intercreditor agreements or
other arrangements giving one or more of such holders priority over the other holders in the collateral held by them or by virtue of structural subordination. 

  
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 SECTION 4.15 SEC Reports. 

(a) Whether or not required by the SEC’s rules and regulations, so long as any Notes are outstanding, the Issuer will furnish to the
Holders, cause the Trustee to furnish to the Holders, or file electronically with the SEC through the SEC’s Electronic Data Gathering, Analysis and Retrieval System (or any successor system, including the Interactive Data Electronic
Applications System), within 15 days after the time periods (including any extensions thereof) applicable to (or that would be applicable to) the Issuer under the SEC’s rules and regulations: 

(1) all quarterly and annual financial information that would be required to be contained in a filing with the SEC on
Forms 10-Q or 10-K (or any successor forms), as the case may be, if the Issuer were required to file these Forms, including a “Management’s Discussion and Analysis of Financial Condition and Results of Operations” and, with
respect to the annual information only, a report on the annual financial statements by the Issuer’s independent accountants; and 

(2) all current reports that would be required to be filed with the SEC on Form 8-K (or any successor form) if the Issuer were
required to file these reports; provided, that the Issuer shall not be obligated to furnish or file (i) any current report on Form 8-K if the Issuer determines in its good faith judgment that the information reportable therein is
not material to the Holders of the Notes or the business, assets, operations, financial position or prospects of the Issuer and its Restricted Subsidiaries, taken as a whole, or (ii) any agreements, financial statements or other items that
would be required to be filed as exhibits to a current report on Form 8-K. 
 In addition, whether or not required by the SEC’s rules and regulations,
the Issuer will file a copy of all of the information and reports referred to in clauses (a)(1) and (a)(2) of this Section 4.15 with the SEC for public availability within the time periods applicable to the Issuer under Section 13(a) or
15(d) of the Exchange Act (unless the SEC will not accept the filing, in which case the Issuer shall make the information available to securities analysts and prospective investors upon request). For so long as any Notes remain outstanding, the
Issuer will furnish to the Holders and to securities analysts and prospective investors, upon their request, the information required to be delivered pursuant to Rule 144A(d)(4) under the Securities Act. The Issuer also shall comply with the other
provisions of Trust Indenture Act § 314(a). 
 (b) Delivery of such reports and information to the Trustee shall be for informational
purposes only and the Trustee’s receipt of them shall not constitute constructive notice of any information contained therein or determinable from information contained therein (including the Issuer’s compliance with any of its covenants
under this Indenture as to which the Trustee is entitled to rely exclusively on an Officers’ Certificate). 

  
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 SECTION 4.16 Limitations on Designation of Unrestricted Subsidiaries. 

(a) The Issuer may designate any Subsidiary of the Issuer (including any newly acquired or newly formed Subsidiary) as an “Unrestricted
Subsidiary” under this Indenture (a “Designation”) only if: 
 (1) no Default shall have occurred and
be continuing at the time of or after giving effect to such Designation; and 
 (2) the Issuer would be permitted to make, at
the time of such Designation, (i) a Permitted Investment or (ii) an Investment pursuant to Section 4.08(a), in either case, in an amount (the “Designation Amount”) equal to the Fair Market Value of the Issuer’s
proportionate interest in such Subsidiary on such date, less, for this purpose, the amount of any intercompany loan from the Issuer or any Restricted Subsidiary to such Subsidiary that was treated as a Restricted Payment. 

(b) No Subsidiary shall be Designated as an “Unrestricted Subsidiary” unless such Subsidiary: 

(1) has no Indebtedness other than Non-Recourse Debt; 

(2) is not party to any agreement, contract, arrangement or understanding with the Issuer or any Restricted Subsidiary unless
the terms of the agreement, contract, arrangement or understanding are no less favorable to the Issuer or the Restricted Subsidiary than those that might be obtained at the time from Persons who are not Affiliates; 

(3) is a Person with respect to which neither the Issuer nor any Restricted Subsidiary has any direct or indirect obligation
(a) to subscribe for additional Equity Interests or (b) to maintain or preserve the Person’s financial condition or to cause the Person to achieve any specified levels of operating results; and 

(4) has not guaranteed or otherwise directly or indirectly provided credit support for any Indebtedness of the Issuer or any
Restricted Subsidiary in excess of $25.0 million in the aggregate, except for any guarantee given solely to support the pledge by the Issuer or any Restricted Subsidiary of the Equity Interests of such Unrestricted Subsidiary, which guarantee is not
recourse to the Issuer or any Restricted Subsidiary, and except to the extent the amount thereof constitutes a Restricted Payment permitted pursuant to Section 4.08. 

(c) If, at any time, any Unrestricted Subsidiary fails to meet the requirements of Section 4.16(a) and (b) as an Unrestricted
Subsidiary, it shall thereafter cease to be an Unrestricted Subsidiary for purposes of this Indenture and any Indebtedness of the Subsidiary and any Liens on assets of such Subsidiary shall be deemed to be incurred by a Restricted Subsidiary as of
the date of such cessation and, if the Indebtedness is not permitted to be incurred under Section 4.07 or the Lien is not permitted under Section 4.09, the Issuer shall be in default of the applicable covenant. 

  
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 (d) The Issuer may redesignate an Unrestricted Subsidiary as a Restricted Subsidiary (a
“Redesignation”) only if: 
 (1) no Default shall have occurred and be continuing at the time of and after
giving effect to such Redesignation; and 
 (2) all Liens, Indebtedness and Investments of such Unrestricted Subsidiary
outstanding immediately following such Redesignation would, if incurred or made at such time, have been permitted to be incurred or made for all purposes of this Indenture. 

(e) All Designations and Redesignations must be evidenced by (1) resolutions of the Board of Directors of the Issuer and (2) an
Officers’ Certificate certifying compliance with the foregoing provisions, in each case delivered to the Trustee. 
 SECTION 4.17 Conduct of
Business. 
 The Issuer will not, and will not permit any Restricted Subsidiary to, engage in any business other than the Permitted
Business. 
 SECTION 4.18 Limitations on Sale and Leaseback Transactions. 

The Issuer will not, and will not permit any Restricted Subsidiary to, directly or indirectly, enter into any Sale and Leaseback Transaction;
provided, however, that the Issuer or any Restricted Subsidiary may enter into a Sale and Leaseback Transaction if: 
 (a) the
Issuer or such Restricted Subsidiary could have (1) incurred the Indebtedness attributable to such Sale and Leaseback Transaction pursuant to Section 4.07 and (2) incurred a Lien to secure such Indebtedness without equally and ratably
securing the Notes pursuant to Section 4.09; 
 (b) the gross cash proceeds of such Sale and Leaseback Transaction are at least equal
to the Fair Market Value of the asset that is the subject of such Sale and Leaseback Transaction; and 
 (c) the transfer of assets in such
Sale and Leaseback Transaction is permitted by, and the Issuer or the applicable Restricted Subsidiary applies the proceeds of such transaction in accordance with, Section 4.10. 

SECTION 4.19 Suspension of Covenants. 

(a) During any period of time following the issuance of the Initial Notes that (i) the Notes have a rating equal to or higher than Baa3
(or the equivalent) by Moody’s and BBB- (or the equivalent) by S&P, or, if either or both shall not make a rating on the Notes publicly available, from a nationally recognized statistical rating agency or agencies, as the case may be,
selected by the Issuer that shall be substituted for Moody’s or S&P or both, as the case may be (Moody’s, S&P or such other agency or agencies, as the case may be, the “Rating Agencies”), an equivalent rating by
such other agency or agencies, as the case may be (any such rating, an “Investment Grade Rating”), and (ii) no Default has occurred and is continuing under this 

  
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Indenture (the occurrence of the events described in the foregoing clauses (i) and (ii) being collectively referred to as a “Covenant Suspension Event”), the Issuer and
the Restricted Subsidiaries shall not be subject to the following provisions of this Indenture: 
  

	 	(1)	Section 4.07; 

  

	 	(2)	Section 4.08; 

  

	 	(3)	Section 4.10; 

  

	 	(4)	Section 4.11; 

  

	 	(5)	Section 4.12; 

  

	 	(6)	Section 4.18; and 

  

	 	(7)	Section 5.01(a)(iii) 

 (collectively, the “Suspended Covenants”). Upon the occurrence of
a Covenant Suspension Event, the amount of Net Available Proceeds with respect to any applicable Asset Sale shall be set at zero at such date (the “Suspension Date”). In the event that the Issuer and the Restricted 

Subsidiaries are not subject to the Suspended Covenants for any period of time as a result of the foregoing, and on any subsequent date (the
“Reversion Date”) one or both of the Rating Agencies withdraws its Investment Grade Rating or downgrades the rating assigned to the Notes below an Investment Grade Rating or a Default occurs and is continuing, then the Issuer and
the Restricted Subsidiaries shall thereafter again be subject to the Suspended Covenants, but only with respect to events after the Reversion Date. The period of time between the Suspension Date and the Reversion Date is referred to as the
“Suspension Period.” Notwithstanding that the Suspended Covenants may be reinstated, no Default will be deemed to have occurred as a result of a failure to comply with the Suspended Covenants during the Suspension Period. 

(b) On the Reversion Date, all Indebtedness incurred during the Suspension Period will be subject to Section 4.07. To the extent such
Indebtedness would not be so permitted to be incurred pursuant to Section 4.07, such Indebtedness will be deemed to have been outstanding on the Issue Date, so that it is classified as permitted under Section 4.07(b)(3). 

(c) Calculations made after the Reversion Date of the amount available to be made as Restricted Payments under Section 4.08 will be made
as though Section 4.08 had been in effect from the Issue Date and throughout the Suspension Period. Accordingly, Restricted Payments made during the Suspension Period will be deemed to have been permitted but will reduce the amount available to
be made as Restricted Payments under Section 4.08(a). 
 (d) The Issuer shall give the Trustee notice of any Covenant Suspension Event
and in any event not later than five (5) Business Days after such Covenant Suspension Event. In the absence of such notice, the Trustee shall assume the Suspended Covenants apply and are in full force and effect. The Issuer shall give the
Trustee notice of any occurrence of a Reversion Date not later than five (5) Business Days after such Reversion Date. After any such notice of the occurrence of a Reversion Date, the Trustee shall assume the Suspended Covenants apply and are in
full force and effect. 

  
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 (e) During a Suspension Period, the Issuer may not designate a Subsidiary as an Unrestricted
Subsidiary under Section 4.16. 
 (f) Notwithstanding the foregoing, neither (1) the continued existence, after the Reversion
Date, of facts and circumstances or obligations that occurred, were incurred or otherwise came into existence during a Suspension Period nor (2) the performance of any such obligations, shall constitute a breach of any Suspended Covenant set
forth in this Indenture or cause a Default hereunder; provided that (i) the Issuer and the Restricted Subsidiaries did not incur or otherwise cause such facts and circumstances or obligations to exist in anticipation of a withdrawal or
downgrade by the applicable Rating Agency below an Investment Grade Rating and (ii) the Issuer reasonably believed that such incurrence or actions would not result in such withdrawal or downgrade. The Issuer shall inform the Trustee of the
occurrence of a Covenant Suspension Event or a Reversion Date and in the absence of any such notice, the Trustee shall be entitled to assume that no such event occurred. 

ARTICLE FIVE 
 SUCCESSOR
CORPORATION 
 SECTION 5.01 Mergers, Consolidations, Etc. 

(a) The Issuer will not, directly or indirectly, in a single transaction or a series of related transactions, (1) consolidate or merge
with or into any other Person (other than a merger with a Wholly-Owned Restricted Subsidiary solely for the purpose of changing the Issuer’s name or jurisdiction of incorporation to another State of the United States), or sell, lease, transfer,
convey or otherwise dispose of or assign all or substantially all of the assets of the Issuer or the Issuer and the Restricted Subsidiaries (taken as a whole) to any other Person or (2) effect a Plan of Liquidation unless, in either case: 

(i) either: 

(x) the Issuer will be the surviving or continuing Person; or 

(y) the Person formed by or surviving such consolidation or merger (if not the Issuer) or to which such sale, lease,
conveyance or other disposition shall be made (or, in the case of a Plan of Liquidation, any Person to which assets are transferred) (collectively, the “Successor”) is a corporation organized and existing under the laws of any State
of the United States of America or the District of Columbia, and the Successor expressly assumes, by a supplemental indenture hereto in form and substance satisfactory to the Trustee, all of the obligations of the Issuer under the Notes and this
Indenture; 
 (ii) immediately after giving effect to such transaction and the assumption of the obligations as set forth in
clause (a)(i)(y) above, if applicable, and the incurrence of any Indebtedness to be incurred in connection therewith, no Default shall have occurred and be continuing; and 

  
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 (iii) except in the case of the consolidation or merger of any Restricted
Subsidiary with or into the Issuer, immediately after giving effect to such transaction and the assumption of the obligations set forth in clause (a)(i)(y) above, if applicable, and the incurrence of any Indebtedness to be incurred in connection
therewith, and the use of any net proceeds therefrom on a pro forma basis, either (A) the Issuer or the Successor, as the case may be, could incur $1.00 of additional Indebtedness pursuant to the Coverage Ratio Exception or (B) the
Consolidated Interest Coverage Ratio of the Issuer or the Successor, as the case may be, determined on a pro forma basis for such transaction, would not be lower than the Consolidated Interest Coverage Ratio of the Issuer immediately prior to
such transaction. 
 For purposes of this Section 5.01, any Indebtedness of the Successor which was not Indebtedness of the Issuer immediately prior to
the transaction shall be deemed to have been incurred in connection with such transaction. 
 (b) Except as provided under Article Eleven,
no Guarantor may consolidate with or merge with or into (whether or not such Guarantor is the surviving Person) another Person (other than the Issuer or another Guarantor), whether or not affiliated with such Guarantor, unless: 

(i) either: 

(x) such Guarantor will be the surviving or continuing Person; or 

(y) the Person formed by or surviving any such consolidation or merger assumes, by supplemental indenture in the form of
Exhibit E attached to this Indenture, all of the obligations of such Guarantor under the Guarantee of such Guarantor and this Indenture; and 

(ii) immediately after giving effect to such transaction, no Default shall have occurred and be continuing. 

(c) For purposes of this Section 5.01, the sale, lease, transfer, conveyance or other disposition or assignment of all or substantially
all of the assets of one or more Restricted Subsidiaries, the Equity Interests of which constitute all or substantially all of the assets of the Issuer, will be deemed to be the transfer of all or substantially all of the assets of the Issuer. 

(d) Except as provided under Article Eleven, upon any consolidation, combination or merger of the Issuer or a Guarantor, or any sale, lease,
transfer, conveyance or other disposition or assignment of all or substantially all of the assets of the Issuer in accordance with the foregoing, in which the Issuer or such Guarantor is not the continuing obligor or continuing guarantor, as the
case may be, under the Notes or its Guarantee, the surviving entity formed by such consolidation or into which the Issuer or such Guarantor is merged or the entity to which the sale, lease, transfer, conveyance or other disposition or assignment is
made will succeed to, 

  
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and be substituted for, and may exercise every right and power of, the Issuer or such Guarantor under this Indenture, the Notes and the Guarantee with the same effect as if such surviving entity
had been named therein as the Issuer or such Guarantor, and, except in the case of a lease, the Issuer or such Guarantor, as the case may be, will be released from the obligation to pay the principal of and interest on the Notes or in respect of its
Guarantee, as the case may be, and all of the Issuer’s or such Guarantor’s other obligations and covenants under the Notes and this Indenture. 

(e) Notwithstanding the foregoing in this Section 5.01, any Restricted Subsidiary may merge into the Issuer or another Restricted
Subsidiary. 
 ARTICLE SIX 

DEFAULT AND REMEDIES 
 SECTION 6.01
Events of Default. 
 Each of the following is an “Event of Default”: 

(1) failure by the Issuer to pay interest on any of the Notes when it becomes due and payable and the continuance of any such
failure for thirty (30) consecutive days (whether or not such payment is prohibited by the subordination provisions of this Indenture); 

(2) failure by the Issuer to pay the principal on any of the Notes when it becomes due and payable, whether at Stated Maturity,
upon redemption, upon purchase, upon acceleration or otherwise (including the failure to make a payment to purchase Notes tendered pursuant to a Change of Control Offer or Net Proceeds Offer on the date specified for such payment in the applicable
offer to purchase, if required) (whether or not such payment is prohibited by the subordination provisions of this Indenture); 

(3) failure by the Issuer to comply with any other agreement or covenant in this Indenture and the continuance of any such
failure for sixty (60) consecutive days after notice of such failure has been given to the Issuer by the Trustee or by the Holders of at least twenty-five percent (25%) of the aggregate principal amount of the Notes then outstanding
(except in the case of a default under Section 5.01, which shall constitute an Event of Default with such notice requirement but without such passage of time requirement); 

(4) default under any mortgage, indenture or other instrument or agreement under which there may be issued or by which there
may be secured or evidenced Indebtedness of the Issuer or any Restricted Subsidiary, whether such Indebtedness exists on the Issue Date or is incurred thereafter, which default: 

(i) is caused by a failure to pay at final maturity (giving effect to any applicable grace periods and any extensions thereof)
principal on such Indebtedness, or 

  
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 (ii) results in the acceleration of such Indebtedness prior to its express final
maturity, 
 and, in each case, the principal amount of such Indebtedness, together with any other Indebtedness with respect to which an
event described in clause (i) or (ii) has occurred and is continuing, aggregates $50.0 million or more; 
 (5)
entry by a court or courts of competent jurisdiction against the Issuer or any Restricted Subsidiary of one or more final judgments or orders for the payment of money that exceed $50.0 million in the aggregate (net of amounts covered by insurance or
bonded) and such judgments or orders have not been satisfied, stayed, annulled or rescinded within sixty (60) days of entry (or such longer period as may be permitted for timely appeal under applicable law); 

(6) the Issuer or any Significant Subsidiary pursuant to or within the meaning of any Bankruptcy Law: 

(i) commences a voluntary case, 

(ii) consents to the entry of an order for relief against it in an involuntary case, 

(iii) consents to the appointment of a Custodian of it or for all or substantially all of its assets, or 

(iv) makes a general assignment for the benefit of its creditors; 

(7) a court of competent jurisdiction enters an order or decree under any Bankruptcy Law that: 

(i) is for relief against the Issuer or any Significant Subsidiary as debtor in an involuntary case, 

(ii) appoints a Custodian of the Issuer or any Significant Subsidiary or a Custodian for all or substantially all of the assets
of the Issuer or any Significant Subsidiary, or 
 (iii) orders the liquidation of the Issuer or any Significant Subsidiary,

 and the order or decree remains unstayed and in effect for sixty (60) days; or 

(8) (i) the Guarantee of any Significant Subsidiary (A) ceases to be in full force and effect (other than in accordance
with the terms of this Indenture (including such Guarantee)) or (B) is declared null and void and unenforceable or found to be invalid, and such circumstance or event remains uncured for a period of thirty (30) days, or (ii) any
Guarantor denies its liability under its Guarantee (other than by reason of release of a Guarantor from its Guarantee in accordance with the terms of this Indenture (including such Guarantee)). 

  
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 SECTION 6.02 Acceleration. 

(a) If an Event of Default specified in Section 6.01(6) or Section 6.01(7) with respect to the Issuer occurs, all outstanding Notes
shall become immediately due and payable without any further action or notice. If an Event of Default (other than an Event of Default specified in Section 6.01(6) or Section 6.01(7) with respect to the Issuer) shall have occurred and be
continuing under this Indenture, the Trustee, by written notice to the Issuer, or the Holders of at least twenty-five percent (25%) in aggregate principal amount of the Notes then outstanding by written notice to the Issuer and the Trustee, may
declare all amounts owing under the Notes to be due and payable, which notice shall specify each applicable Event of Default and that it is a “notice of acceleration” (an “Acceleration Notice”). Upon proper delivery of an
Acceleration Notice, the aggregate principal of and accrued and unpaid interest on the outstanding Notes shall become due and payable (a) if there is any Designated Senior Debt outstanding at such time, with respect to any acceleration arising
out of any Event of Default other than a payment default under Section 6.01(1) or Section 6.01(2), upon the earlier of (x) the date which is five (5) Business Days after receipt by the Representatives of such Acceleration Notice
or (y) the date of acceleration of any Designated Senior Debt and (b) if otherwise, immediately, but, in any case, only if one or more of the Events of Default specified in such Acceleration Notice are then continuing; provided,
however, that after such declaration of acceleration, but before a judgment or decree based on acceleration, the Holders of at least a majority in aggregate principal amount of the then outstanding Notes may, on behalf of all of the Holders,
rescind and annul such declaration of acceleration and its consequences: 
 (1) if the rescission would not conflict with any
judgment or decree; 
 (2) if all existing Events of Default have been cured or waived (except nonpayment of principal and
interest that has become due solely because of such declaration of acceleration); 
 (3) to the extent the payment of such
interest is lawful, interest on overdue installments of interest and overdue principal, which has become due (otherwise than by such declaration of acceleration), has been paid; and 

(4) if the Issuer has paid to the Trustee its reasonable compensation and reimbursed the Trustee of its expenses, disbursements
and advances; 
 (5) in the event of a cure or waiver of an Event of Default of the type set forth in Section 6.01(6) or
Section 6.01(7), the Trustee shall have received an Officers’ Certificate and an Opinion of Counsel that such Event of Default has been cured or waived. 

No such rescission shall affect any subsequent Default or impair any right consequent thereto. 

(b) The Issuer shall provide prompt notice to the holders of Senior Debt and Guarantor Senior Debt of any acceleration pursuant to
Section 6.02(a). 

  
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 SECTION 6.03 Other Remedies. 

If a Default occurs and is continuing, the Trustee may pursue any available remedy by proceeding at law or in equity to collect the payment of
principal of, or interest on, the Notes or to enforce the performance of any provision of the Notes or this Indenture. 
 The Trustee may
maintain a proceeding even if it does not possess any of the Notes or does not produce any of them in the proceeding. A delay or omission by the Trustee or any Holder in exercising any right or remedy accruing upon a Default shall not impair the
right or remedy or constitute a waiver of or acquiescence in the Default. No remedy is exclusive of any other remedy. All remedies are cumulative to the extent permitted by law. 

SECTION 6.04 Waiver of Past Defaults. 

Subject to Section 2.09, Section 6.07 and Section 9.02, the Holders of at least a majority in aggregate principal amount of the
then outstanding Notes, by notice to the Trustee, may, on behalf of all of the Holders of such Notes, waive (which may include waivers obtained in connection with a tender offer or exchange offer for Notes), an existing Default and its consequences,
except a Default in the payment of principal or interest on such Notes as specified in Section 6.01(1) or Section 6.01(2). When a Default is waived, it is cured and ceases. 

SECTION 6.05 Control by Majority. 

(a) The Holders of at least a majority in principal amount of the then outstanding Notes shall have the right to direct the time, method and
place of conducting any proceeding for exercising any remedy available to the Trustee or exercising any trust or power conferred on it. Subject to Section 7.01, however, the Trustee may refuse to follow any direction that conflicts with any law
or this Indenture, that the Trustee determines may be unduly prejudicial to the rights of another Holder, or that may involve the Trustee in personal liability; provided, however, that the Trustee may take any other action deemed
proper by the Trustee which is not inconsistent with such direction. 
 (b) In the event the Trustee takes any action or follows any
direction pursuant to this Indenture, the Trustee shall be entitled to indemnification against any loss or expense caused by taking such action or following such direction. 

SECTION 6.06 Limitation on Suits. 

(a) Subject to Section 6.07, no Holder will have any right to institute any proceeding with respect to this Indenture or the Notes or for
any remedy thereunder, unless the Trustee: 
 (1) has failed to act for a period of sixty (60) consecutive days after
receiving notice of a continuing Event of Default from such Holder and a request to act by Holders of at least twenty-five percent (25%) in aggregate principal amount of the then outstanding Notes; 

(2) has been offered indemnity satisfactory to it in its reasonable judgment; and 

  
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 (3) has not received from the Holders of a majority in aggregate principal amount
of the then outstanding Notes a direction inconsistent with such request. 
 (b) A Holder may not use this Indenture to prejudice the rights
of another Holder or to obtain a preference or priority over another Holder (it being understood that the Trustee does not have an affirmative duty to ascertain whether or not such actions or forbearances are unduly prejudicial to such Holders).

 SECTION 6.07 Rights of Holders to Receive Payment. 

Notwithstanding any other provision of this Indenture, the right of any Holder to receive payment of principal of, and interest on, a Note, on
or after the respective due dates expressed in such Note (including, if applicable, in connection with an offer to purchase or redeem), or to bring suit for the enforcement of any such payment on or after such respective dates, shall not be impaired
or affected without the consent of such Holder. 
 SECTION 6.08 Collection Suit by Trustee. 

If a Default in payment of principal or interest specified in Section 6.01(1) or Section 6.01(2) occurs and is continuing, the
Trustee may recover judgment in its own name and as trustee of an express trust against the Issuer or any other obligor on the Notes for the whole amount of principal and accrued interest and fees remaining unpaid, together with interest on overdue
principal and, to the extent that payment of such interest is lawful, interest on overdue installments of interest, in each case at the rate per annum borne by the Notes and such further amount as shall be sufficient to cover the costs and
expenses of collection, including the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel. 

SECTION 6.09 Trustee May File Proofs of Claim. 

The Trustee may file such proofs of claim and other papers or documents as may be necessary or advisable in order to have the claims of the
Trustee (including any claim for the compensation, expenses, disbursements and advances of the Trustee, its agents and counsel) and the Holders allowed in any judicial proceedings relating to the Issuer, their creditors or their property and shall
be entitled and empowered to collect and receive any monies or other property payable or deliverable on any such claims and to distribute the same, and any Custodian in any such judicial proceeding is hereby authorized by each Holder to make such
payments to the Trustee and, in the event that the Trustee shall consent to the making of such payments directly to the Holders, to pay to the Trustee any amount due to it for the reasonable compensation, expenses, disbursements and advances of the
Trustee, its agent and counsel, and any other amounts due the Trustee under this Indenture. Nothing herein contained shall be deemed to authorize the Trustee to authorize or consent to or accept or adopt on behalf of any Holder any plan of
reorganization, arrangement, adjustment or composition affecting the Notes or the rights of any Holder thereof, or to authorize the Trustee to vote in respect of the claim of any Holder in any such proceeding. The Trustee shall be entitled to
participate as a member of any official committee of creditors in the matters as it deems necessary or advisable. 

  
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 SECTION 6.10 Priorities. 

If the Trustee collects any money or property pursuant to this Article Six, it shall pay out the money or property in the following order: 

First: to the Trustee for amounts due under Section 7.07; 

Second: to Holders for interest accrued on the Notes, ratably, without preference or priority of any kind, according to the amounts due
and payable on the Notes for interest; 
 Third: to Holders for principal amounts due and unpaid on the Notes, ratably, without
preference or priority of any kind, according to the amounts due and payable on the Notes for principal; and 
 Fourth: to the Issuer
or, if applicable, the Guarantors, as their respective interests may appear, or to such other Person or Persons as a court of competent jurisdiction shall direct. 

The Trustee, upon prior notice to the Issuer, may fix a record date and payment date for any payment to Holders pursuant to this
Section 6.10. 
 SECTION 6.11 Undertaking for Costs. 

In any suit for the enforcement of any right or remedy under this Indenture or in any suit against the Trustee for any action taken or omitted
by it as the Trustee, a court in its discretion may require the filing by any party litigant in the suit of an undertaking to pay the costs of the suit, and the court in its discretion may assess reasonable costs, including reasonable
attorneys’ fees and expenses, against any party litigant in the suit, having due regard to the merits and good faith of the claims or defenses made by the party litigant. This Section 6.11 does not apply to a suit by the Trustee, a suit by
a Holder pursuant to Section 6.07, or a suit by a Holder or Holders of more than ten percent (10%) in aggregate principal amount of the then outstanding Notes. 

ARTICLE SEVEN 
 TRUSTEE 

SECTION 7.01 Duties of Trustee. 
 (a)
If a Default has occurred and is continuing, the Trustee shall exercise such of the rights and powers vested in it by this Indenture and use the same degree of care and skill in their exercise as a prudent Person would exercise or use under the
circumstances in the conduct of his or her own affairs. 
 (b) Except during the continuance of a Default: 

(1) the Trustee need perform only those duties as are specifically set forth herein or in the Trust Indenture Act and no
duties, covenants, responsibilities or obligations shall be implied in this Indenture against the Trustee; and 
 (2) in the
absence of bad faith on its part, the Trustee may conclusively rely, as to the truth of the statements and the correctness of the opinions expressed therein, 

  
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upon certificates (including Officers’ Certificates) or opinions (including Opinions of Counsel) furnished to the Trustee and conforming to the requirements of this Indenture. However, in
the case of any such certificates or opinions which by any provision hereof are specifically required to be furnished to the Trustee, the Trustee shall examine the certificates and opinions to determine whether or not they conform to the
requirements of this Indenture (but need not confirm or investigate the accuracy of mathematical calculations or other facts stated therein). 

(c) Notwithstanding anything to the contrary in this Indenture, the Trustee may not be relieved from liability for its own negligent action,
its own negligent failure to act, or its own willful misconduct, except that: 
 (1) this paragraph does not limit the effect
of Section 7.01(b); 
 (2) the Trustee shall not be liable for any error of judgment made in good faith by a Responsible
Officer, unless it is proved that the Trustee was negligent in ascertaining the pertinent facts; and 
 (3) the Trustee shall
not be liable with respect to any action it takes or omits to take in good faith in accordance with a direction received by it pursuant to Section 6.05. 

(d) No provision of this Indenture shall require the Trustee to expend or risk its own funds or otherwise incur any financial liability in the
performance of any of its duties hereunder or to take or omit to take any action under this Indenture or take any action at the request or direction of Holders if it shall have reasonable grounds for believing that repayment of such funds is not
assured to it. 
 (e) Whether or not therein expressly so provided, every provision of this Indenture that in any way relates to the Trustee
is subject to this Section 7.01. 
 (f) The Trustee shall not be liable for interest on any money received by it except as the Trustee
may agree in writing with the Issuer. Money held in trust by the Trustee need not be segregated from other funds except to the extent required by law. 

(g) In the absence of bad faith, negligence or willful misconduct on the part of the Trustee, the Trustee shall not be responsible for the
application of any money by any Paying Agent other than the Trustee. 
 SECTION 7.02 Rights of Trustee. 

Subject to Section 7.01: 

(a) The Trustee may rely conclusively on any resolution, certificate (including any Officers’ Certificate), statement, instrument,
opinion (including any Opinion of Counsel), notice, request, direction, consent, order, bond, debenture, or other paper or document believed by it to be genuine and to have been signed or presented by the proper Person. The Trustee need not
investigate any fact or matter stated in such document. 

  
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 (b) Before the Trustee acts or refrains from acting, it may require an Officers’ Certificate
and an Opinion of Counsel, which shall conform to the provisions of Section 12.05. The Trustee shall not be liable for any action it takes or omits to take in good faith in reliance on such Officers’ Certificate or Opinion of Counsel. 

(c) The Trustee may act through its attorneys and agents and shall not be responsible for the misconduct or negligence of any agent (other
than an agent who is an employee of the Trustee) appointed with due care. 
 (d) The Trustee shall not be liable for any action it takes or
omits to take in good faith which it reasonably believes to be authorized or within its rights or powers under this Indenture. 
 (e) The
Trustee may consult with counsel of its selection and the advice or opinion of such counsel as to matters of law shall be full and complete authorization and protection from liability in respect of any action taken, omitted or suffered by it
hereunder in good faith and in accordance with the advice or opinion of such counsel. 
 (f) The Trustee shall be under no obligation to
exercise any of the rights or powers vested in it by this Indenture at the request, order or direction of any of the Holders pursuant to the provisions of this Indenture, unless such Holders shall have offered to the Trustee security or indemnity
reasonably satisfactory to it against the costs, expenses and liabilities which may be incurred therein or thereby. 
 (g) The Trustee shall
not be bound to make any investigation into the facts or matters stated in any resolution, certificate (including any Officers’ Certificate), statement, instrument, opinion (including any Opinion of Counsel), notice, request, direction,
consent, order, bond, debenture, or other paper or document, but the Trustee, in its discretion, may make such further inquiry or investigation into such facts or matters as it may see fit and, if the Trustee shall determine to make such further
inquiry or investigation, it shall be entitled, upon reasonable notice to the Issuer, to examine the books, records, and premises of the Issuer, personally or by agent or attorney at the sole cost of the Issuer. 

(h) The Trustee shall not be required to give any bond or surety in respect of the performance of its powers and duties hereunder. 

(i) The permissive rights of the Trustee to do things enumerated in this Indenture shall not be construed as duties. 

(j) Except with respect to Section 4.01 and Section 4.04, the Trustee shall have no duty to inquire as to the performance of the
Issuer with respect to the covenants contained in Article Four. In addition, the Trustee shall not be deemed to have knowledge of any Default except (i) any Default occurring pursuant to Section 4.01, Section 4.04,
Section 6.01(1) or Section 6.01(2) or (ii) any Default of which the Trustee shall have received written notification. 
 (k)
The rights, privileges, protections, immunities and benefits given to the Trustee, including its right to be indemnified, are extended to, and shall be enforceable by, the Trustee in each of its capacities hereunder, and to each agent, custodian and
other Person employed to act for it hereunder. 

  
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 (l) In no event shall the Trustee be responsible or liable for special, indirect, punitive or
consequential loss or damage of any kind whatsoever (including, but not limited to, loss of profit) irrespective of whether the Trustee has been advised of the likelihood of such loss or damage and regardless of the form of action. 

(m) The Trustee may request that the Issuer deliver a certificate setting forth the names of individuals or titles of officers authorized at
such time to take specified actions pursuant to this Indenture. 
 SECTION 7.03 Individual Rights of Trustee. 

The Trustee in its individual or any other capacity may become the owner or pledgee of Notes and may otherwise deal with the Issuer, its
Subsidiaries or their respective Affiliates with the same rights it would have if it were not Trustee. Any Agent may do the same with like rights. However, the Trustee must comply with Sections 7.10 and 7.11. 

SECTION 7.04 Trustee’s Disclaimer. 

The Trustee shall not be responsible for and makes no representation as to the validity or adequacy of this Indenture or the Notes, it shall
not be accountable for the Issuer’s use of the proceeds from the Notes, and it shall not be responsible for any statement of the Issuer in this Indenture or any document issued in connection with the sale of Notes or any statement in the Notes
other than the Trustee’s certification of its authentication. 
 SECTION 7.05 Notice of Default. 

If a Default occurs and is continuing, the Trustee shall mail to each Holder, notice of the uncured Default within thirty (30) days after
it occurs or, if later, after the Trustee is deemed to have knowledge of such Default (pursuant to this Indenture). Except in the case of a Default in payment of principal of or interest on any Note, including an accelerated payment and the failure
to make a payment on the Change of Control Payment Date pursuant to a Change of Control Offer or the Net Proceeds Payment Date pursuant to a Net Proceeds Offer, or a Default in complying with the provisions of Article Five, the Trustee may withhold
the notice if and so long as the Board of Directors, the executive committee, or a trust committee of directors or Responsible Officers, of the Trustee in good faith determines that withholding the notice is in the interests of the Holders. 

SECTION 7.06 Reports by Trustee to Holders. 

Within sixty (60) days after each June 1, beginning with June 1, 2016, the Trustee shall, to the extent that any of the events
described in Trust Indenture Act § 313(a) occurred within the previous twelve months, but not otherwise, mail to each Holder a brief report dated as of such date that complies with Trust Indenture Act § 313(a). The Trustee also shall
comply with Trust Indenture Act §§313(b), 313(c) and 313(d). 
 A copy of each report at the time of its mailing to Holders shall
be filed with the SEC and each securities exchange, if any, on which the Notes are listed. 

  
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 The Issuer shall promptly notify the Trustee if the Notes become listed on any securities
exchange or of any delisting thereof and the Trustee shall comply with Trust Indenture Act § 313(d). 
 SECTION 7.07 Compensation and
Indemnity. 
 The Issuer shall pay to the Trustee from time to time such compensation as the Issuer and the Trustee shall from time to
time agree in writing for its services hereunder. The Trustee’s compensation shall not be limited by any law on compensation of a trustee of an express trust. The Issuer shall reimburse the Trustee upon request for all reasonable disbursements,
expenses and advances (including reasonable fees and expenses of counsel) incurred or made by it in addition to the compensation for its services, except any such disbursements, expenses and advances as may be attributable to the Trustee’s
negligence, bad faith or willful misconduct. Such expenses shall include the reasonable fees and expenses of the Trustee’s agents and counsel. 

The Issuer shall indemnify each of the Trustee or any predecessor Trustee and its agents for, and hold them harmless against, any and all
loss, damage, claims (including taxes (other than taxes based upon, measured by or determined by the income of the Trustee)), liability or expense incurred by them arising out of or in connection with the acceptance or administration of this trust
(including the reasonable costs and expenses of defending themselves against or investigating any claim or liability in connection with the exercise or performance of any of the Trustee’s rights, powers or duties hereunder), except in each of
the foregoing cases to the extent caused by any negligence, bad faith or willful misconduct on their part. The Trustee shall notify the Issuer promptly of any claim asserted against the Trustee or any of its agents for which it may seek indemnity.
The Issuer may, subject to the approval of the Trustee (which approval shall not be unreasonably withheld), defend the claim and the Trustee shall cooperate in the defense. The Trustee and its agents subject to the claim may have separate counsel
and the Issuer shall pay the reasonable fees and expenses of such counsel; provided, however, that the Issuer will not be required to pay such fees and expenses if, subject to the approval of the Trustee (which approval shall not be
unreasonably withheld), it assumes the Trustee’s defense and there is no conflict of interest between the Issuer and the Trustee and its agents subject to the claim in connection with such defense as reasonably determined by the Trustee. The
Issuer need not pay for any settlement made without its written consent. The Issuer need not reimburse any expense or indemnify against any loss or liability to the extent incurred by the Trustee through its negligence, bad faith or willful
misconduct. 
 When the Trustee incurs expenses or renders services after a Default specified in Section 6.01(6) or
Section 6.01(7) occurs, such expenses and the compensation for such services shall be paid to the extent allowed under any Bankruptcy Law. 

The Trustee shall have a lien prior to the Notes as to all property and funds held by it hereunder for any amount owing it or any predecessor
Trustee pursuant to this Section 7.07, except with respect to funds held in trust for the benefit of the Holders. 

  
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 Notwithstanding any other provision in this Indenture, the foregoing provisions of this
Section 7.07 shall survive the satisfaction and discharge of this Indenture or the appointment of a successor Trustee. 
 SECTION 7.08
Replacement of Trustee. 
 The Trustee may resign by so notifying the Issuer at least thirty (30) days prior to the date of the
proposed resignation. The Holders of at least a majority in principal amount of the then outstanding Notes may remove the Trustee by so notifying the Issuer and the Trustee and may appoint a successor Trustee. The Issuer may remove the Trustee if:

 (1) the Trustee fails to comply with Section 7.10; 

(2) the Trustee is adjudged a bankrupt or an insolvent; 

(3) a receiver or other public officer takes charge of the Trustee or its property; or 

(4) the Trustee becomes incapable of acting. 

If the Trustee retires, whether by resignation or removal, or if a vacancy exists in the office of Trustee for any reason, the Issuer shall
notify each Holder of such event and shall promptly appoint a successor Trustee. Within one (1) year after the successor Trustee takes office, the Holders of at least a majority in principal amount of the then outstanding Notes may appoint a
successor Trustee to replace the successor Trustee appointed by the Issuer. 
 A successor Trustee shall deliver a written acceptance of its
appointment to the retiring Trustee and to the Issuer. Promptly after that, the retiring Trustee shall transfer, and after payment of all sums then owing to the Trustee pursuant to Section 7.07, all property held by it as Trustee to the
successor Trustee, the resignation or removal of the retiring Trustee shall become effective, and the successor Trustee shall have all the rights, powers and duties of the Trustee with respect to the Notes under this Indenture. A successor Trustee
shall mail notice of its succession to each Holder. 
 If a successor Trustee does not take office within sixty (60) days after the
retiring Trustee resigns or is removed, the retiring Trustee, the Issuer or the Holders of at least ten percent (10%) in principal amount of the then outstanding Notes may petition any court of competent jurisdiction for the appointment of a
successor Trustee at the expense of the Issuer. 
 If the Trustee fails to comply with Section 7.10, any Holder may petition any court
of competent jurisdiction for the removal of the Trustee and the appointment of a successor Trustee. 
 Notwithstanding the appointment of a
successor Trustee pursuant to this Section 7.08, the Issuer’s obligations under Section 7.07 shall continue for the benefit of the retiring Trustee. 

  
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 SECTION 7.09 Successor Trustee by Merger, Etc. 

If the Trustee consolidates with, merges or converts into, or transfers all or substantially all of its corporate trust business to, another
corporation, the resulting, surviving or transferee corporation without any further act shall, if such resulting, surviving or transferee corporation is otherwise eligible hereunder, be the successor Trustee; provided, however, that
such corporation shall be otherwise qualified and eligible under this Article Seven. 
 SECTION 7.10 Eligibility; Disqualification. 

The Trustee shall at all times satisfy the requirements of Trust Indenture Act §§ 310(a)(1), 310(a)(2) and 310(a)(5). The Trustee
shall have a combined capital and surplus of at least $50,000,000 as set forth in its most recent published annual report of condition. The Trustee shall comply with Trust Indenture Act § 310(b); provided, however, that there
shall be excluded from the operation of Trust Indenture Act § 310(b)(1) any indenture or indentures under which other securities, or certificates of interest or participation in other securities, of the Issuer are outstanding, if the
requirements for such exclusion set forth in Trust Indenture Act § 310(b)(1) are met. The provisions of Trust Indenture Act § 310 shall apply to the Issuer and any other obligor of the Notes. 

SECTION 7.11 Preferential Collection of Claims Against the Issuer. 

The Trustee, in its capacity as Trustee hereunder, shall comply with Trust Indenture Act § 311(a), excluding any creditor relationship
listed in Trust Indenture Act § 311(b). A Trustee who has resigned or been removed shall be subject to Trust Indenture Act § 311(a) to the extent indicated. 

ARTICLE EIGHT 
 DISCHARGE OF
INDENTURE; DEFEASANCE 
 SECTION 8.01 Termination of the Issuer’s Obligations. 

Except as otherwise provided in the penultimate paragraph of this Section 8.01, this Indenture and the Guarantees will be discharged and
will cease to be of further effect (except as to rights of registration of transfer or exchange of Notes, which shall survive until all Notes have been canceled) as to all outstanding Notes, when either: 

(a) all the Notes that have been authenticated and delivered (except lost, stolen or destroyed Notes that have been replaced or paid and Notes
for whose payment money has been deposited in trust or segregated and held in trust by the Issuer and thereafter repaid to the Issuer or discharged from this trust) have been delivered to the Trustee for cancellation; or 

(b) (1) all Notes that have not been delivered to the Trustee for cancellation either (i) have become due and payable by reason of the
mailing of a notice of redemption pursuant to Section 5 or Section 7 of the Notes, Section 4.06(i) or otherwise or (ii) will become due and payable within one year, and in each of the foregoing cases the Issuer has irrevocably
deposited or caused to be deposited with the Trustee as trust funds in trust 

  
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solely for the benefit of the Holders funds in Dollars or U.S. Government Obligations in amounts sufficient (without reinvestment) to pay and discharge the entire Indebtedness (including all
principal and accrued interest) on the Notes not theretofore delivered to the Trustee for cancellation to the date of maturity or redemption, 

(2) the Issuer or any Guarantor has paid or caused to be paid all other sums payable by the Issuer under this Indenture, 

(3) the Issuer has delivered irrevocable instructions to the Trustee to apply the deposited money toward the payment of the
Notes at maturity or on the date of redemption, as the case may be, and 
 (4) the Holders have a valid, perfected, exclusive
security interest in such trust. 
 In addition, the Issuer must deliver an Officers’ Certificate and an Opinion of Counsel to the
Trustee stating that all conditions precedent to satisfaction and discharge have been complied with. 
 In the case of clause (b) of
this Section 8.01, and subject to the next sentence and notwithstanding the foregoing paragraph, the Issuer’s obligations in Sections 2.05, 2.06, 2.07, 2.08, 4.01, 4.02, 4.03 (as to legal existence of the Issuer only), 7.07, 8.05 and 8.06
shall survive until the Notes are no longer outstanding pursuant to the last paragraph of Section 2.08. In addition, nothing in this Section 8.01 shall be deemed to discharge the obligations in Sections 7.07, 8.04(a), 8.05 or 8.06, all of
which shall survive the satisfaction and discharge of this Indenture. 
 After such delivery or irrevocable deposit, the Trustee upon
request by the Issuer shall acknowledge in writing the discharge of the Issuer’s obligations under the Notes and this Indenture except for the surviving obligations specified above. 

SECTION 8.02 Legal Defeasance and Covenant Defeasance. 

(a) The Issuer may, at its option and at any time, elect to have either Section 8.02(b) or 8.02(c) applied to all outstanding Notes upon
compliance with the conditions set forth below in this Article Eight. 
 (b) Upon the Issuer’s exercise under Section 8.02(a) of
the option applicable to this Section 8.02(b), the Issuer and the Guarantors shall, subject to the satisfaction of the conditions set forth in Section 8.03, be deemed to have been discharged from its or their obligations with respect to
all outstanding Notes and Guarantees on the date the conditions set forth below are satisfied (hereinafter, “Legal Defeasance”). For this purpose, Legal Defeasance means that the Issuer and the Guarantors shall be deemed to have
paid and discharged the entire Indebtedness represented by the outstanding Notes and the Guarantees, which shall thereafter be deemed to be “outstanding” only for the purposes of Section 8.04 and the other Sections of this Indenture
referred to in clauses (1) and (2) below, and to have satisfied all its or their other obligations under such Notes, such Guarantees and this Indenture (and the Trustee, on demand of and at the

  
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expense of the Issuer, shall execute proper instruments acknowledging the same), except for the following provisions which shall survive until otherwise terminated or discharged hereunder: 

(1) the rights of Holders of outstanding Notes to receive, solely from the trust fund described in Section 8.04, and as
more fully set forth in such Section 8.04, payments in respect of the principal of, and interest on, such Notes when such payments are due; 

(2) the Issuer’s obligations with respect to such Notes under Article Two and Section 4.02; 

(3) the rights, powers, trusts, duties and immunities of the Trustee hereunder and the Issuer’s obligations in connection
therewith; and 
 (4) the provisions of this Article Eight applicable to Legal Defeasance (including Sections 8.04, 8.05 and
8.06). 
 Subject to compliance with this Article Eight, the Issuer may exercise its option under this Section 8.02(b) notwithstanding
the prior exercise of its option under Section 8.02(c). 
 (c) Upon the Issuer’s exercise under
Section 8.02(a) of the option applicable to this Section 8.02(c), the Issuer and each of the Guarantors shall, subject to the satisfaction of the conditions set forth in Section 8.03, be released from each of their respective
obligations under the covenants contained in Sections 4.03 (other than with respect to the legal existence of the Issuer), 4.04, and 4.06 through 4.18, clause (iii) of Section 5.01(a) and Article Eleven with respect to the outstanding
Notes on and after the date the conditions set forth in Section 8.03 are satisfied (hereinafter, “Covenant Defeasance”), and the Notes shall thereafter be deemed not “outstanding” for the purposes of any direction,
waiver, consent or declaration or act of Holders (and the consequences of any thereof) in connection with such covenants, but shall continue to be deemed “outstanding” for all other purposes hereunder (it being understood that such Notes
shall not be deemed outstanding for accounting purposes). For this purpose, Covenant Defeasance means that, with respect to the outstanding Notes, the Issuer and the Guarantors may omit to comply with and shall have no obligation or liability in
respect of any term, condition or limitation set forth in any such covenant, whether directly or indirectly, by reason of any reference elsewhere herein to any such covenant or by reason of any reference in any such covenant to any other provision
herein or in any other document and such omission to comply shall not constitute a Default under Section 6.01, but, except as specified above, the remainder of this Indenture and such Notes shall be unaffected thereby. In addition, upon the
Issuer’s exercise under Section 8.02(a) of the option applicable to this Section 8.02(c), subject to the satisfaction of the conditions set forth in Section 8.03 hereof, clauses (3), (4), (5) and (8), and, after
the expiration of the period of ninety-one (91) days immediately following the deposit referred to in Section 8.03(1) (and so long as no Event of Default under clause (6) or (7) of Section 6.01 exists at the time of the
expiration of such period), clauses (6) and (7) of Section 6.01 shall not constitute Events of Default. 

  
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 SECTION 8.03 Conditions to Legal Defeasance or Covenant Defeasance. 

In order to exercise either Legal Defeasance under Section 8.02(b) or Covenant Defeasance under Section 8.02(c) with respect to the
outstanding Notes: 
 (1) the Issuer must irrevocably deposit with the Trustee, in trust, for the benefit of the Holders,
funds in Dollars or U.S. Government Obligations or a combination thereof, in such amounts as will be sufficient (without reinvestment), in the opinion of a nationally recognized firm of independent public accountants selected by the Issuer, to pay
the principal of and interest on the outstanding Notes on the stated date for payment thereof or on the applicable Redemption Date, as the case may be, and the Issuer must specify to the Trustee whether such Notes are being defeased to such stated
date for payment or to a particular Redemption Date, as the case may be and the Holders must have a valid, perfected, exclusive security interest in such trust; 

(2) in the case of Legal Defeasance, the Issuer shall have delivered to the Trustee an Opinion of Counsel in
the United States reasonably acceptable to the Trustee confirming that: 
 (i) the Issuer has received from, or
there has been published by the Internal Revenue Service, a ruling, or 
 (ii) since the Issue Date, there has been a change
in the applicable U.S. federal income tax law, 
 in either case to the effect that, and based thereon this Opinion of Counsel shall confirm that, the
Holders will not recognize income, gain or loss for U.S. federal income tax purposes as a result of such Legal Defeasance and will be subject to U.S. federal income tax on the same amounts, in the same manner and at the same times as would have been
the case if such Legal Defeasance had not occurred; 
 (3) in the case of Covenant Defeasance, the Issuer shall have
delivered to the Trustee an Opinion of Counsel in the United States reasonably acceptable to the Trustee confirming that the Holders will not recognize income, gain or loss for U.S. federal income tax purposes as a result of such Covenant
Defeasance and will be subject to U.S. federal income tax on the same amounts, in the same manner and at the same times as would have been the case if such Covenant Defeasance had not occurred; 

(4) no Default shall have occurred and be continuing on the date of such deposit (other than a Default resulting from the
borrowing of funds to be applied to such deposit and the grant of any Lien securing such borrowing); 
 (5) the Legal
Defeasance or Covenant Defeasance shall not result in a breach or violation of, or constitute a default under (other than any such default resulting solely from the borrowing of funds to be applied to such deposit and the grant of any Lien on such
deposit in favor of the Trustee or the Holders) any Credit Agreement or any other material agreement or instrument to which the Issuer or any of its Subsidiaries is a party or by which the Issuer or any of its Subsidiaries is bound; 

  
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 (6) the Issuer shall have delivered to the Trustee an Officers’ Certificate
stating that the deposit was not made by the Issuer with the intent of preferring the Holders over any other creditors of the Issuer or with the intent of defeating, hindering, delaying or defrauding any other of its creditors or others; and 

(7) the Issuer shall have delivered to the Trustee an Officers’ Certificate and an Opinion of Counsel, stating, in the
case of the Officers’ Certificate, that the conditions provided for in clauses (1) through (6) of this Section 8.03, as applicable, have been complied with and stating, in the case of the Opinion of Counsel, that clause
(1) (with respect to the validity and perfection of the security interest) and the conditions provided for in clause (2) or (3), as applicable, and clause (5) of this Section 8.03 have been complied with. 

Notwithstanding anything to the contrary herein, the borrowing of funds to be applied to any deposit, and the grant of any Lien securing such
borrowing, in order to effect any Legal Defeasance or Covenant Defeasance, shall not constitute a Default under this Indenture. 
 SECTION 8.04
Application of Trust Money. 
 (a) The Trustee or Paying Agent shall hold in trust all funds and U.S. Government Obligations
(including the proceeds thereof) deposited with it pursuant to this Article Eight in respect of the outstanding Notes, and shall apply the deposited funds and U.S. Government Obligations (including any proceeds thereof) in accordance with this
Indenture to the payment of the principal of and the interest on the Notes. The Trustee shall be under no obligation to invest said funds and U.S. Government Obligations (including any proceeds thereof), except as it may agree with the Issuer. 

(b) The Issuer shall pay and indemnify the Trustee against any tax, fee or other charge imposed on or assessed against the funds or U.S.
Government Obligations (including any proceeds thereof) deposited pursuant to Section 8.03, or the principal and interest received in respect thereof, other than any such tax, fee or other charge which by law is for the account of the Holders
of the outstanding Notes. 
 (c) Anything in this Article Eight to the contrary notwithstanding, the Trustee shall promptly deliver or pay
to the Issuer from time to time upon the request of the Issuer any funds or and U.S. Government Obligations held by it as provided in Section 8.03 which, in the opinion of a nationally recognized firm of independent public accountants expressed
in a written certification thereof delivered to the Trustee, are in excess of the amount thereof that would then be required to be deposited to effect an equivalent Legal Defeasance or Covenant Defeasance. 

SECTION 8.05 Repayment to the Issuer. 

Any funds or U.S. Government Obligations deposited with the Trustee or any Paying Agent, or then held by the Issuer, in trust for the payment
of the principal of or interest on the Notes and remaining unclaimed for two (2) years after such principal or interest has become due and payable shall be repaid to the Issuer on its request or (if then held by the Issuer) will be discharged
from such trust; and the Holders will thereafter be permitted to look only to the Issuer (unless an applicable law designates another Person) for payment thereof, and all liability of the 

  
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Trustee or such Paying Agent with respect to such trust funds, and all liability of the Issuer as trustee thereof, will thereupon cease; provided, however, that the Trustee or such
Paying Agent, before being required to make any such repayment, shall at the expense of the Issuer cause to be published once, in the New York Times and The Wall Street Journal (national edition), or mail to each Holder entitled to such funds,
notice that such money remains unclaimed and that, after a date specified therein, which will not be less than thirty (30) days from the date of such publication or mailing, any unclaimed balance of such money then remaining will be repaid to
the Issuer. 
 SECTION 8.06 Reinstatement. 

If the Trustee or Paying Agent is unable to apply any funds and U.S. Government Obligations in accordance with this Article Eight by reason of
any legal proceeding or by reason of any order or judgment of any court or governmental authority enjoining, restraining or otherwise prohibiting such application, or if the funds deposited with the Trustee to effect Covenant Defeasance are
insufficient to pay the principal of, and interest on, the Notes when due, then the Issuer’s obligations under this Indenture and the Notes shall be revived and reinstated as though no deposit had occurred pursuant to this Article Eight until
such time as the Trustee or Paying Agent is permitted to apply all such funds and U.S. Government Obligations in accordance with this Article Eight; provided, however, that if the Issuer has made any payment of interest on, or
principal of, any Notes because of the reinstatement of its obligations, the Issuer shall be subrogated to the rights of the Holders of such Notes to receive such payment from the funds and U.S. Government Obligations held by the Trustee or Paying
Agent. 
 ARTICLE NINE 

AMENDMENTS, SUPPLEMENTS AND WAIVERS 

SECTION 9.01 Without Consent of Holders. 

Subject to Section 9.03, the Issuer, the Guarantors and the Trustee, as applicable, together, may amend or supplement this Indenture
(including the Guarantees) or the Notes without notice to or consent of any Holder: 
 (1) to cure any ambiguity, defect or
inconsistency, 
 (2) to provide for uncertificated Notes in addition to or in place of certificated Notes, 

(3) to provide for the assumption of the Issuer’s or any Guarantor’s obligations to the Holders in the case of a
merger, consolidation or sale of all or substantially all of the Issuer’s assets, in accordance with Article Five, 

(4) to add Guarantees with respect to the Notes, 

(5) to release any Guarantor from its Guarantee or any of its other obligations under this Indenture (to the extent permitted
by this Indenture), 

  
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 (6) to make any change that would provide any additional rights or benefits to
the Holders or that adds covenants of the Issuer or any Guarantor for the benefit of the Holders, or to surrender any right or power conferred upon the Issuer or any Guarantor, 

(7) to make any change that does not materially adversely affect the rights of any Holder hereunder or under the Notes, 

(8) to comply with requirements of the SEC in order to effect or maintain the qualification of this Indenture under, or to
otherwise comply with, the Trust Indenture Act, 
 (9) to conform the text of this Indenture or the Notes to any provision of
the “Description of Notes” section of the Offering Memorandum to the extent that such provision in such “Description of Notes” section was intended to be a substantially verbatim recitation of a provision of this Indenture or the
Notes, or 
 (10) to evidence and provide for the acceptance of appointment under this Indenture by a successor Trustee with
respect to the Notes and to add or change any of the provisions of this Indenture as shall be necessary to provide for or facilitate the administration of the trusts hereunder by more than one Trustee, 

provided that the Issuer has delivered to the Trustee an Opinion of Counsel and an Officers’ Certificate, each stating that such amendment or
supplement complies with the provisions of this Section 9.01. 
 SECTION 9.02 With Consent of Holders. 

(a) Subject to Section 6.07 and Section 9.03, the Issuer, the Guarantors and the Trustee, with the written consent (which may include
consents obtained in connection with a tender offer or exchange offer for Notes) of the Holder or Holders of at least a majority in aggregate principal amount of the then outstanding Notes may amend or supplement this Indenture (including the
Guarantees) or the Notes without notice to any other Holders. Subject to Section 6.07 and Section 9.03, the Holder or Holders of at least a majority in aggregate principal amount of the then outstanding Notes may waive (which may include
waivers obtained in connection with a tender offer or exchange offer for Notes) compliance with any provision of this Indenture (including the Guarantees) or the Notes without notice to any other Holders. 

(b) Notwithstanding Section 9.02(a), without the consent of each Holder affected, no amendment or waiver may (with respect to any Notes
held by a non-consenting Holder): 
 (1) reduce the principal or change the Stated Maturity of any Note; 

(2) reduce the rate of or extend the time for payment of interest on any Note; 

(3) reduce any premium payable upon optional redemption of the Notes, change the date on which any Notes are subject to
redemption or otherwise alter the provisions with respect to the redemption of the Notes (other than provisions relating to the purchase of Notes set forth in Section 4.06 (other than Section 4.06(i)) and Section 4.10, 

  
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 except that if a Change of Control has occurred, no amendment or other modification of the
obligation of the Issuer to make a Change of Control Offer relating to such Change of Control shall be made without the consent of each Holder affected); 

(4) make the principal of or interest, if any, on any Note payable in money or currency other than that stated in the Notes;

 (5) modify or change any provision of this Indenture or the related definitions affecting the subordination of the Notes
or the Guarantees in a manner that adversely affects the Holders in any material respect; 
 (6) release any Guarantor which
is a Significant Subsidiary from any of its obligations under its Guarantee or this Indenture other than as provided in this Indenture; 

(7) waive a Default in the payment of principal of or interest on any Notes (except a rescission of acceleration of the Notes
by the Holders of at least a majority in principal amount of the then outstanding Notes as provided in this Indenture and a waiver of the payment Default that resulted from such acceleration); 

(8) impair the rights of Holders to receive payments of principal of or interest on the Notes on or after the due date
therefor; 
 (9) reduce the principal amount of outstanding Notes whose Holders must consent to an amendment, supplement or
waiver to or under this Indenture (including the Guarantees) or the Notes; or 
 (10) make any change in Section 6.07 or
this Section 9.02. 
 (c) It shall not be necessary for the consent of the Holders of the Notes under this Section 9.02 to approve
the particular form of any proposed amendment, supplement or waiver but it shall be sufficient if such consent approves the substance thereof. 

(d) A consent to any amendment, supplement or waiver under this Indenture by any Holder given in connection with an exchange (in the case of
an exchange offer) or a tender (in the case of a tender offer) of such Holder’s Notes will not be rendered invalid by such tender or exchange. 

(e) After an amendment, supplement or waiver under this Section 9.02 becomes effective, the Issuer shall mail, or cause to be mailed, to
the Holders affected thereby a notice briefly describing the amendment, supplement or waiver. Any failure of the Issuer to mail such notice, or any defect therein, shall not, however, in any way impair or affect the validity of any such amendment,
supplement or waiver. 
 SECTION 9.03 Effect on Senior Debt. 

No amendment of, or supplement or waiver to, this Indenture shall adversely affect the rights of any holder of Senior Debt or Guarantor Senior
Debt under Article Ten and Section 11.02 without the consent of such holder or its Representative. 

  
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 SECTION 9.04 Compliance with the Trust Indenture Act. 

Every amendment to this Indenture or the Notes shall be set forth in a supplemental indenture hereto that complies with the Trust Indenture Act
as then in effect. 
 SECTION 9.05 Revocation and Effect of Consents. 

Until an amendment, supplement or waiver becomes effective, a consent to it by a Holder is a continuing consent by the Holder and every
subsequent Holder of a Note or portion of a Note that evidences the same debt as the consenting Holder’s Note, even if notation of the consent is not made on any Note. However, any such Holder or subsequent Holder may revoke the consent as to
his Note or portion of his Note by notice to the Trustee or the Issuer received before the date on which the Trustee receives an Officers’ Certificate certifying that the Holders of the requisite principal amount of Notes have consented (and
not theretofore revoked such consent) to the amendment, supplement or waiver. 
 The Issuer may, but shall not be obligated to, fix a record
date for the purpose of determining the Holders entitled to consent to any amendment, supplement or waiver, which record date shall be any date the Issuer shall select for such purpose. If a record date is fixed, then notwithstanding the last
sentence of the immediately preceding paragraph, those Persons who were Holders at such record date (or their duly designated proxies), and only those Persons, shall be entitled to revoke any consent previously given, whether or not such Persons
continue to be Holders after such record date. No such consent shall be valid or effective for more than ninety (90) days after such record date. The Issuer shall inform the Trustee in writing of the fixed record date if applicable. 

After an amendment, supplement or waiver becomes effective, it shall bind every Holder, unless it makes a change described in any of clauses
(1) through (10) of Section 9.02(b), in which case, the amendment, supplement or waiver shall bind only each Holder of a Note who has consented to it and every subsequent Holder of a Note or portion of a Note that evidences the same
debt as the consenting Holder’s Note; provided, however, that no such amendment, supplement or waiver shall impair or affect the right of any Holder to receive payment of principal of, and interest on, a Note, on or after the
respective due dates therefor, or to bring suit for the enforcement of any such payment on or after such respective dates without the consent of such Holder. 

SECTION 9.06 Notation on or Exchange of Notes. 

If an amendment, supplement or waiver changes the terms of a Note, the Issuer may require the Holder of the Note to deliver it to the Trustee.
The Issuer shall provide the Trustee with an appropriate notation on the Note about the changed terms and cause the Trustee to return it to the Holder at the Issuer’s expense. Alternatively, if the Issuer or the Trustee so determines, the
Issuer in exchange for the Note shall issue, and the Trustee shall authenticate, a new Note that reflects the changed terms. Failure to make the appropriate notation or issue a new Note shall not affect the validity and effect of such amendment,
supplement or waiver. 

  
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 SECTION 9.07 Trustee To Sign Amendments, Etc. 

The Trustee shall execute any amendment, supplement or waiver authorized pursuant to this Article Nine; provided, however, that
the Trustee may, but shall not be obligated to, execute any such amendment, supplement or waiver which affects the Trustee’s own rights, duties or immunities under this Indenture. The Trustee shall be entitled to receive, and (subject to
Section 7.01) shall be fully protected in conclusively relying upon, an Opinion of Counsel and an Officers’ Certificate each stating that the execution of any amendment, supplement or waiver authorized pursuant to this Article Nine is
authorized or permitted by this Indenture. Such Opinion of Counsel shall be at the expense of the Issuer. 
 ARTICLE TEN 

SUBORDINATION OF NOTES 
 SECTION 10.01
Notes Subordinated to Senior Debt. 
 Anything herein to the contrary notwithstanding, each of the Issuer, for itself and its
successors, and each Holder, by his or her acceptance of Notes (whether upon original issue or upon transfer, assignment or exchange of Notes), agrees that the payment of all Obligations owing to the Holders in respect of the Notes is subordinated,
to the extent and in the manner provided in this Article Ten, to the prior payment in full of all Senior Debt (including all Obligations under any Credit Facility (including any Credit Agreement) and all Obligations under the Senior Notes) in cash,
whether outstanding on the Issue Date or thereafter incurred. Notwithstanding anything in this Article Ten to the contrary, payments and distributions (a) of Permitted Junior Securities and (b) made relating to the Notes from the trust
established pursuant to Article Eight shall not be so subordinated in right of payment, so long as, with respect to (b), (1) the conditions specified in Article Eight are satisfied on the date of any deposit pursuant to said trust and
(2) such payments and distributions did not violate the provisions of this Article Ten when made. 
 The Notes shall in all respects
rank pari passu in right of payment with (i) the Existing Senior Subordinated Notes and any Indebtedness of the Issuer that expressly provides that it ranks pari passu in right of payment with any of the Existing Senior
Subordinated Notes and (ii) the 2007 Convertible Notes (as in effect on the date hereof) and any Indebtedness of the Issuer that expressly provides that it ranks pari passu in right of payment with the 2007 Convertible Notes (as in
effect on the date hereof), and only Indebtedness of the Issuer which is Senior Debt shall rank senior to the Notes in accordance with the provisions set forth herein. 

This Article Ten shall constitute a continuing offer to all Persons who become holders of, or continue to hold, Senior Debt, such provisions
are made for the benefit of the holders of Senior Debt and such holders are made obligees hereunder and any one or more of them may enforce such provisions. 

The holders of Senior Debt (including Designated Senior Debt) shall have the right to rely on this Article Ten. 

  
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 SECTION 10.02 Suspension of Payment When Senior Debt Is in Default. 

(a) If any default occurs and is continuing in the payment when due (beyond any applicable grace period), whether at maturity, upon any
redemption, by declaration or otherwise, of any principal of, interest on, unpaid drawings for letters of credit issued in respect of, or fees with respect to, any Designated Senior Debt (a “Payment Default”), then the Issuer shall
not (x) make any payment or distribution of any kind or character with respect to any Obligations on or relating to the Notes or (y) acquire any of the Notes for cash or assets or otherwise (other than, in either case, Permitted Junior
Securities). 
 (b) If any other event of default (other than a Payment Default) occurs and is continuing with respect to any Designated
Senior Debt (as such event of default is defined in the instrument creating or evidencing such Designated Senior Debt) permitting the holders of such Designated Senior Debt then outstanding to accelerate the maturity thereof (a “Non-Payment
Default”) and if the Representative for the respective issue of Designated Senior Debt (including, as applicable, the administrative agent under any Credit Facility (including any Credit Agreement)) gives written notice of the Non-Payment
Default to the Trustee stating that such notice is a payment blockage notice (a “Payment Blockage Notice”), then during the period (the “Payment Blockage Period”) beginning upon the delivery of such Payment Blockage
Notice and ending on the earliest of (1) the date on which all such Non-Payment Defaults are cured or waived, (2) one hundred seventy-nine (179) days after the date on which the applicable Payment Blockage Notice is received or
(3) the date on which the Trustee receives notice from the Representative for such Designated Senior Debt rescinding the Payment Blockage Notice (unless in each case the maturity of any Designated Senior Debt has been accelerated), the Issuer
shall not (x) make any payment of any kind or character with respect to any Obligations on or with respect to the Notes or (y) acquire any of the Notes for cash or assets or otherwise (other than, in either case, Permitted Junior
Securities). Notwithstanding anything herein to the contrary, (x) in no event will a Payment Blockage Period extend beyond one hundred seventy-nine (179) days from the date the applicable Payment Blockage Notice is received by the Trustee
and (y) no new Payment Blockage Notice may be delivered unless and until 360 days have elapsed since the effectiveness of the immediately prior Payment Blockage Notice. For all purposes of this Section 10.02(b), no Non-Payment Default
which existed or was continuing on the date of the commencement of any Payment Blockage Period with respect to the Designated Senior Debt shall be, or be made, the basis for the commencement of a second Payment Blockage Period by the
Representative of such Designated Senior Debt whether or not within a period of 360 consecutive days, unless such Non-Payment Default shall have been cured or waived for a period of not less than ninety (90) consecutive days. Any
subsequent action, or any breach of any financial covenants for a period ending after the date of commencement of such Payment Blockage Period that, in either case, would give rise to a Non-Payment Default pursuant to any provisions under which a
Non-Payment Default previously existed or was continuing shall constitute a new Non-Payment Default for this purpose. 
 (c) In the event
that, notwithstanding the foregoing, any payment shall be received by the Trustee or any Holder when such payment is prohibited by the foregoing provisions of this Section 10.02, such payment shall be held in trust for the benefit of, and shall
be paid over or delivered to, the holders of Senior Debt (pro rata to such holders on the basis of the respective amount of Senior Debt held by such holders) or their respective Representatives, as their respective interests may appear. The
Trustee shall be entitled to rely on information regarding amounts outstanding on the Senior Debt, if any, received from the holders of the Senior Debt (or their Representatives). 

  
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 (d) Nothing contained in this Article Ten shall limit the right of the Trustee or the Holders of
the Notes to take any action to accelerate the maturity of the Notes pursuant to Section 6.02 or to pursue any rights or remedies hereunder; provided, however, that all Senior Debt thereafter due or declared to be due shall first
be paid in full in cash or cash equivalents before the Holders are entitled to receive any payment of any kind or character with respect to Obligations on the Notes. 

SECTION 10.03 Notes Subordinated to Prior Payment of All Senior Debt on Dissolution, Liquidation or Reorganization of the Issuer. 

(a) Upon any payment or distribution of assets of the Issuer of any kind or character, whether in cash, assets or securities, to creditors upon
any total or partial liquidation, dissolution, winding-up, assignment for the benefit of creditors or marshaling of assets and liabilities of the Issuer or in a bankruptcy, reorganization, insolvency, receivership or other similar proceeding
relating to the Issuer or its assets, whether voluntary or involuntary, all Obligations due on all Senior Debt (including interest accruing after the commencement of any bankruptcy or other like proceeding at the rate specified in any Credit
Facility (including any Credit Agreement) or in the Senior Notes, as applicable, whether or not such interest is an allowed claim in any such proceeding) shall first be paid in full in cash, or such payment duly provided for to the satisfaction of
the holders of Senior Debt, before any payment or distribution of any kind or character is made on account of any Obligations on or relating to the Notes. Upon any such dissolution, winding-up, liquidation, reorganization, receivership or similar
proceeding, any payment or distribution of assets of the Issuer of any kind or character, whether in cash, assets or securities, to which the Holders of the Notes or the Trustee under this Indenture would be entitled, except for the provisions
hereof, shall be paid by the Issuer or by any receiver, trustee in bankruptcy, liquidating trustee, agent or other Person making such payment or distribution, or by the Holders or by the Trustee under this Indenture if received by them, directly to
the holders of Senior Debt (pro rata to such holders on the basis of the respective amounts of Senior Debt held by such holders) or their respective Representatives, or to the trustee or trustees under any indenture pursuant to which any of
such Senior Debt may have been issued, as their respective interests may appear, for application to the payment of Senior Debt remaining unpaid until all such Senior Debt has been paid in full in cash after giving effect to any concurrent payment,
distribution or provision therefor to or for the holders of Senior Debt. 
 (b) To the extent any payment of Senior Debt (whether by or on
behalf of the Issuer, as proceeds of security or enforcement of any right of setoff or otherwise) is declared to be fraudulent or preferential, set aside or required to be paid to any receiver, trustee in bankruptcy, liquidating trustee, agent or
other similar Person under any bankruptcy, insolvency, receivership, fraudulent conveyance or similar law, then, if such payment is recovered by, or paid over to, such receiver, trustee in bankruptcy, liquidating trustee, agent or other similar
Person, the Senior Debt or part thereof originally intended to be satisfied shall be for purpose of this Article Ten deemed to be reinstated and outstanding as if such payment had not occurred. 

  
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 It is further agreed that any diminution (whether pursuant to court decree or otherwise,
including without limitation for any of the reasons described in the preceding sentence) of the Issuer’s obligation to make any distribution or payment pursuant to any Senior Debt, except to the extent such diminution occurs by reason of the
repayment (which has not been disgorged or returned) of such Senior Debt in cash or cash equivalents, shall have no force or effect for purposes of the subordination provisions contained in this Article Ten, with any turnover of payments as
otherwise calculated pursuant to this Article Ten to be made as if no such diminution had occurred. 
 (c) In the event that,
notwithstanding the foregoing, any payment or distribution of assets of the Issuer of any kind or character, whether in cash, assets or securities, shall be received by any Holder when such payment or distribution is prohibited by this
Section 10.03, such payment or distribution shall be held in trust for the benefit of, and shall be paid over or delivered to, the holders of Senior Debt (pro rata to such holders on the basis of the respective amount of Senior Debt held
by such holders) or their respective Representatives, or to the trustee or trustees under any indenture pursuant to which any of such Senior Debt may have been issued, as their respective interests may appear, for application to the payment of
Senior Debt remaining unpaid until all such Senior Debt has been paid in full in cash or cash equivalents, after giving effect to any concurrent payment, distribution or provision therefor to or for the holders of such Senior Debt. 

(d) The consolidation of the Issuer with, or the merger of the Issuer with or into, another Person or the liquidation or dissolution of the
Issuer following the conveyance or transfer of all or substantially all of its assets, to another Person upon the terms and conditions provided in Article Five hereof shall not be deemed a dissolution, winding-up, liquidation or reorganization for
the purposes of this Section if such other Person shall, as a part of such consolidation, merger, conveyance or transfer, assume the Issuer’s obligations hereunder in accordance with Article Five hereof. 

SECTION 10.04 Payments May Be Made on Notes. 

Nothing contained in this Article Ten or elsewhere in this Indenture shall prevent (a) the Issuer, except under the conditions described
in Sections 10.02 and 10.03, from making payments at any time for the purpose of making payments of principal of, and interest on, the Notes, or from depositing with the Trustee any moneys for such payments, or (b) in the absence of actual
knowledge by the Trustee that a given payment would be prohibited by Section 10.02 or 10.03, the application by the Trustee of any moneys deposited with it for the purpose of making such payments of principal of, and interest on, the Notes to
the Holders entitled thereto unless at least two (2) Business Days prior to the date upon which such payment would otherwise become due and payable a Responsible Officer of the Trustee shall have actually received the written notice provided
for in the first sentence of Section 10.02(b) or in Section 10.07; provided, however, that, notwithstanding the foregoing, the Holders receiving any payments made in contravention of Section 10.02 or 10.03 (and the
respective such payments) shall otherwise be subject to the provisions of Section 10.02 and Section 10.03. Notwithstanding anything to the contrary contained in this Article Ten or elsewhere in this Indenture, payments and distributions
from the funds deposited pursuant to Article Eight will be permitted to be made and will not be subject to the provisions of this Article Ten so long as such funds were deposited 

  
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in accordance with the provisions of Article Eight and did not violate the provisions of this Article Ten when such funds were so deposited. The Issuer shall give prompt written notice to the
Trustee of any dissolution, winding-up, liquidation or reorganization of the Issuer, although any delay or failure to give any such notice shall have no effect on the subordination provisions contained herein. 

SECTION 10.05 Holders To Be Subrogated to Rights of Holders of Senior Debt. 

Subject to the payment in full of all Senior Debt in cash or cash equivalents, the Holders of the Notes shall be subrogated to the rights of
the holders of Senior Debt to receive payments or distributions of cash, assets or securities of the Issuer applicable to the Senior Debt until the Notes shall be paid in full; and, for the purposes of such subrogation, no such payments or
distributions to the holders of the Senior Debt by or on behalf of the Issuer, or by or on behalf of the Holders by virtue of this Article Ten, which otherwise would have been made to the Holders shall, as between the Issuer and the Holders, be
deemed to be a payment by the Issuer to or on account of the Senior Debt, it being understood that the provisions of this Article Ten are and are intended solely for the purpose of defining the relative rights of the Holders, on the one hand, and
the holders of Senior Debt, on the other hand. 
 SECTION 10.06 Obligations of the Issuer Unconditional. 

Nothing contained in this Article Ten or elsewhere in this Indenture or in the Notes is intended to or shall impair, as between the Issuer, and
the Holders, the obligation of the Issuer, which is absolute and unconditional, to pay to the Holders the principal of, and any interest on, the Notes as and when the same shall become due and payable in accordance with their terms, or is intended
to or shall affect the relative rights of the Holders and creditors of the Issuer other than the holders of the Senior Debt, nor shall anything herein or therein prevent the Holder of any Note or the Trustee on its behalf from exercising all
remedies otherwise permitted by applicable law upon default under this Indenture, subject to the rights, if any, of the holders of Senior Debt in respect of cash, assets or securities of the Issuer received upon the exercise of any such remedy. 

SECTION 10.07 Notice to Trustee. 

The Issuer shall give prompt written notice to the Trustee of any fact known to the Issuer which would prohibit the making of any payment to or
by the Trustee in respect of the Notes pursuant to the provisions of this Article Ten, although any delay or failure to give any such notice shall have no effect on the subordination provisions contained herein. Regardless of anything to the
contrary contained in this Article Ten or elsewhere in this Indenture, the Trustee shall not be charged with knowledge of the existence of any default or event of default with respect to any Senior Debt or of any other facts which would prohibit the
making of any payment to or by the Trustee unless and until the Trustee shall have received notice in writing from the Issuer, or from a holder of Senior Debt or a Representative therefor and, prior to the receipt of any such written notice, the
Trustee shall be entitled to assume (in the absence of actual knowledge to the contrary) that no such facts exist. The Trustee shall be entitled to rely on the delivery to it of any notice pursuant to this Section 10.07 to establish that such
notice has been given by a holder of Senior Debt (or a Representative thereof). 

  
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 In the event that the Trustee determines in good faith that any evidence is required with respect
to the right of any Person as a holder of Senior Debt to participate in any payment or distribution pursuant to this Article Ten, the Trustee may request such Person to furnish evidence to the satisfaction of the Trustee as to the amounts of Senior
Debt held by such Person, the extent to which such Person is entitled to participate in such payment or distribution and any other facts pertinent to the rights of such Person under this Article Ten, and if such evidence is not furnished the Trustee
may defer any payment to such Person pending judicial determination as to the right of such Person to receive such payment. 
 SECTION 10.08
Reliance on Judicial Order or Certificate of Liquidating Agent. 
 Upon any payment or distribution of assets of the Issuer referred
to in this Article Ten, the Trustee, subject to the provisions of Article Seven hereof, and the Holders of the Notes shall be entitled to rely upon any order or decree made by any court of competent jurisdiction in which any insolvency, bankruptcy,
receivership, dissolution, winding-up, liquidation, reorganization or similar case or proceeding is pending, or upon a certificate of the receiver, trustee in bankruptcy, liquidating trustee, assignee for the benefit of creditors, agent or other
Person making such payment or distribution, delivered to the Trustee or the Holders of the Notes, for the purpose of ascertaining the Persons entitled to participate in such payment or distribution, the holders of the Senior Debt and other
Indebtedness of the Issuer, the amount thereof or payable thereon, the amount or amounts paid or distributed thereon and all other facts pertinent thereto or to this Article Ten. 

SECTION 10.09 Trustee’s Relation to Senior Debt. 

The Trustee and any agent of the Issuer or the Trustee shall be entitled to all the rights set forth in this Article Ten with respect to any
Senior Debt which may at any time be held by it in its individual or any other capacity to the same extent as any other holder of Senior Debt and nothing in this Indenture shall deprive the Trustee or any such agent of any of its rights as such
holder. 
 With respect to the holders of Senior Debt, the Trustee undertakes to perform or to observe only such of its covenants and
obligations as are specifically set forth in this Article Ten, and no implied covenants or obligations with respect to the holders of Senior Debt shall be read into this Indenture against the Trustee. The Trustee shall not be deemed to owe any
fiduciary duty to the holders of Senior Debt. 
 Whenever a distribution is to be made or a notice given to holders or owners of Senior
Debt, the distribution may be made and the notice may be given to their Representative, if any. 
 SECTION 10.10 Subordination Rights Not Impaired
by Acts or Omissions of the Issuer or Holders of Senior Debt. 
 No right of any present or future holders of any Senior Debt to enforce
subordination as provided herein shall at any time in any way be prejudiced or impaired by any act or failure to act on the part of the Issuer or by any act or failure to act, in good faith, by any such holder, or by any noncompliance by the Issuer
with the terms of this Indenture, regardless of any knowledge thereof, which any such holder may have or otherwise be charged with. 

  
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 Without in any way limiting the generality of the foregoing paragraph, the holders of Senior Debt
may, at any time and from time to time, without the consent of or notice to the Trustee, without incurring responsibility to the Trustee or the Holders of the Notes and without impairing or releasing the subordination provided in this Article Ten or
the obligations hereunder of the Holders of the Notes to the holders of the Senior Debt, do any one or more of the following: (a) change the manner, place or terms of payment or extend the time of payment of, or renew or alter, Senior Debt, or
otherwise amend or supplement in any manner Senior Debt, or any instrument evidencing the same or any agreement under which Senior Debt is outstanding; (b) sell, exchange, release or otherwise deal with any property pledged, mortgaged or
otherwise securing Senior Debt; (c) release any Person liable in any manner for the payment or collection of Senior Debt; and (d) exercise or refrain from exercising any rights against the Issuer and any other Person. 

SECTION 10.11 Holders Authorize Trustee To Effectuate Subordination of Notes. 

Each Holder of the Notes by its acceptance of them (whether upon original issue or upon transfer, assignment or exchange of Notes) authorizes
and expressly directs the Trustee on its behalf to take such action as may be necessary or appropriate to effectuate, as between the holders of Senior Debt and the Holders of the Notes, the subordination provided in this Article Ten, and appoints
the Trustee its attorney-in-fact for such purposes, including, in the event of any dissolution, winding-up, liquidation or reorganization of the Issuer (whether in bankruptcy, insolvency, receivership, reorganization or similar proceedings or upon
an assignment for the benefit of credits or otherwise) tending towards liquidation of the business and assets of the Issuer, the filing of a claim for the unpaid balance of its Notes and accrued interest in the form required in those proceedings.

 If the Trustee does not file a proper claim or proof of debt in the form required in such proceeding prior to thirty (30) days
before the expiration of the time to file such claim or claims, then the holders of the Senior Debt or their Representative are or is hereby authorized to have the right to file and are or is hereby authorized to file an appropriate claim for and on
behalf of the Holders of said Notes. Nothing herein contained shall be deemed to authorize the Trustee or the holders of Senior Debt or their Representative to authorize, consent to, accept or adopt on behalf of any Holder any plan of
reorganization, arrangement, adjustment or composition affecting the Notes or the rights of any Holder thereof, or to authorize the Trustee or the holders of Senior Debt or their Representative to vote in respect of the claim of any Holder in any
such proceeding. 
 SECTION 10.12 This Article Ten Not To Prevent Events of Default. 

The failure to make a payment on account of principal of, or interest on, the Notes by reason of any provision of this Article Ten will not be
construed as preventing the occurrence of an Event of Default. 
 SECTION 10.13 Trustee’s Compensation Not Prejudiced. 

Nothing in this Article Ten will apply to amounts due to the Trustee (other than payments of Obligations owing to Holders in respect of the
Notes) pursuant to other Sections of this Indenture. 

  
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 ARTICLE ELEVEN 

GUARANTEE 
 SECTION 11.01 Unconditional
Guarantee. 
 Subject to the provisions of this Article Eleven, each of the Guarantors, jointly and severally, hereby unconditionally and
irrevocably guarantees to each Holder of a Note authenticated and delivered by the Trustee and to the Trustee and its successors and assigns, irrespective of the validity and enforceability of this Indenture, the Notes or the obligations of the
Issuer to the Holders or the Trustee hereunder or thereunder: (a) (x) the due and punctual payment of the principal of and interest on the Notes when and as the same shall become due and payable, whether at maturity, upon redemption or
repurchase, by acceleration or otherwise, (y) the due and punctual payment of interest on the overdue principal and (to the extent permitted by law) interest, if any, on the Notes and (z) the due and punctual payment and performance of all
other obligations of the Issuer to the Holders or the Trustee hereunder or thereunder (including amounts due the Trustee under Section 7.07 hereof), all in accordance with the terms hereof and thereof (collectively, the “Guarantee
Obligations”); and (b) in case of any extension of time of payment or renewal of any Notes or any of such other obligations, the due and punctual payment and performance of Guarantee Obligations in accordance with the terms of the
extension or renewal, whether at maturity, upon redemption or repurchase, by acceleration or otherwise. Failing payment when due of any amount so guaranteed, or failing performance of any other obligation of the Issuer to the Holders under this
Indenture or under the Notes, for whatever reason, each Guarantor shall be obligated to pay, or to perform or cause the performance of, the same immediately. A Default under this Indenture or the Notes shall constitute an event of default under the
Guarantees, and shall entitle the Holders to accelerate the obligations of the Guarantors under the Guarantees in the same manner and to the same extent as the obligations of the Issuer. 

Each of the Guarantors hereby agrees that its obligations hereunder shall be unconditional, irrespective of the validity, regularity or
enforceability of the Notes or this Indenture, the absence of any action to enforce the same, any waiver or consent by any Holder of the Notes with respect to any provisions hereof or thereof, any release of any other Guarantor, the recovery of any
judgment against the Issuer, any action to enforce the same, or any other circumstance which might otherwise constitute a legal or equitable discharge or defense of a Guarantor. Each of the Guarantors hereby waives the benefit of diligence,
presentment, demand of payment, filing of claims with a court in the event of insolvency or bankruptcy of the Issuer, any right to require a proceeding first against the Issuer, protest, notice and all demands whatsoever and covenants that its
Guarantee shall not be discharged except by complete performance of the obligations contained in the Notes and this Indenture (including the Guarantees). Each Guarantee is a guarantee of payment and not of collection. If any Holder or the Trustee is
required by any court or otherwise to return to the Issuer or to any Guarantor, or any custodian, trustee, liquidator or other similar official acting in relation to the Issuer or such Guarantor, any amount paid by the Issuer or such Guarantor to
the Trustee or such Holder, each Guarantee, to the extent theretofore discharged, shall be reinstated in full force and effect. Each Guarantor further agrees that, as between it, on the one hand, and the Holders of Notes and the Trustee, on the
other hand, (a) subject to this Article Eleven, the maturity of the obligations 

  
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guaranteed hereby may be accelerated as provided in Article Six, notwithstanding any stay, injunction or other prohibition preventing such acceleration in respect of the obligations guaranteed
hereby, and (b) in the event of any acceleration of such obligations as provided in Article Six, such obligations (whether or not due and payable) shall forthwith become due and payable by the Guarantors for the purpose of the Guarantees. 

SECTION 11.02 Subordination of Guarantee. 

The obligations of each Guarantor under its Guarantee pursuant to this Article Eleven shall be junior and subordinated to the prior payment in
full of the Guarantor Senior Debt of such Guarantor, whether outstanding on the Issue Date or thereafter incurred, in cash on the same basis as the Notes are junior and subordinated to Senior Debt of the Issuer. For the purposes of the foregoing
sentence, the Trustee and the Holders shall have the right to receive or retain payments by any of the Guarantors only at such times as they may receive or retain payments in respect of the Notes pursuant to this Indenture, including Article Ten. In
addition to the foregoing provisions of this Section 11.02, all of the covenants, obligations and agreements contained in Article Ten (together with related definitions) shall be deemed incorporated in this Section 11.02, mutatis
mutandis, as if references to the Issuer therein are references to each Guarantor herein and references to Senior Debt therein are references to the Guarantor Senior Debt of such Guarantor herein. 

SECTION 11.03 Limitation on Guarantor Liability. 

Each Guarantor, and by its acceptance of Notes, each Holder, hereby confirms that it is the intention of all such parties that the Guarantee of
such Guarantor not constitute a fraudulent transfer or conveyance for purposes of Bankruptcy Law, the Uniform Fraudulent Conveyance Act, the Uniform Fraudulent Transfer Act or any similar federal, foreign or state law to the extent applicable to any
Guarantee. To effectuate the foregoing intention, the Trustee, the Holders and the Guarantors hereby irrevocably agree that the obligations of such Guarantor under this Article Eleven shall be limited to the maximum amount as will, after giving
effect to all other contingent and fixed liabilities of such Guarantor (including any guarantee under any Credit Facility (including any Credit Agreement) permitted under Section 4.07(b)(1) and including such Guarantor’s guarantees of the
Issuer’s obligations under the Senior Notes, the Senior Notes Indenture, the Existing Senior Subordinated Notes and the Existing Senior Subordinated Notes Indentures) that are relevant under such laws, and after giving effect to any collections
from, rights to receive contribution from or payments made by or on behalf of any other Guarantor in respect of the obligations of such other Guarantor under this Article Eleven, result in the obligations of such Guarantor under its Guarantee not
constituting a fraudulent transfer or conveyance under any such applicable federal, foreign or state law. Each Guarantor that makes a payment for distribution under its Guarantee is entitled to a contribution from each other Guarantor in a pro
rata amount based on the adjusted net assets of each Guarantor. 

  
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 SECTION 11.04 Release of a Guarantor. 

A Guarantor shall be released from its obligations under its Guarantee and this Indenture: 

(1) in the event of a sale or other disposition of all or substantially all of the assets of such Guarantor, by way of merger,
consolidation or otherwise, or a sale or other disposition of all of the Equity Interests of such Guarantor then held by the Issuer and the Restricted Subsidiaries; 

(2) if such Guarantor is designated as an Unrestricted Subsidiary or otherwise ceases to be a Restricted Subsidiary, in each
case in accordance with the provisions of this Indenture, upon effectiveness of such designation or when it first ceases to be a Restricted Subsidiary, respectively; or 

(3) if such Guarantor shall not guarantee any Indebtedness or other Obligation under any Credit Agreement (other than if such
Guarantor no longer guarantees any Indebtedness or other Obligation under such Credit Agreement as a result of payment under any guarantee of any such Indebtedness or other Obligation by such Guarantor); provided, however, that a
Guarantor shall not be permitted to be released from its Guarantee or the Indenture if it is an obligor with respect to any Indebtedness or other Obligation that would not, under Section 4.07, be permitted to be incurred by a Restricted
Subsidiary that is not a Guarantor. 
 The Trustee shall execute an appropriate instrument prepared by the Issuer evidencing the release of
a Guarantor from its obligations under its Guarantee and this Indenture upon receipt of a request by the Issuer or such Guarantor accompanied by an Officers’ Certificate and an Opinion of Counsel certifying as to the compliance with this
Section 11.04. 
 Nothing contained in this Indenture or in any of the Notes shall prevent any consolidation or merger of a Guarantor
with or into the Issuer (in which case such Guarantor shall no longer be a Guarantor) or another Guarantor or shall prevent any sale or conveyance of the property of a Guarantor as an entirety or substantially as an entirety to the Issuer or another
Guarantor. 
 SECTION 11.05 Waiver of Subrogation. 

Until this Indenture is discharged and all of the Notes are discharged and paid in full, each Guarantor hereby irrevocably waives and agrees
not to exercise any claim or other rights which it may now or hereafter acquire against the Issuer that arise from the existence, payment, performance or enforcement of the Issuer’s obligations under the Notes or this Indenture and such
Guarantor’s obligations under its Guarantee and this Indenture, in any such instance including any right of subrogation, reimbursement, exoneration, contribution, indemnification, and any right to participate in any claim or remedy of the
Holders against the Issuer, whether or not such claim, remedy or right arises in equity, or under contract, statute or common law, including the right to take or receive from the Issuer, directly or indirectly, in cash or other assets or by set-off
or in any other manner, payment or security on account of such claim or other rights. If any amount shall be paid to any Guarantor in violation of the preceding sentence and any amounts owing to the Trustee or the Holders of Notes under the Notes,
this Indenture, or any other document or instrument delivered under or in connection with such agreements or instruments, shall not have been paid in full, such amount shall have been deemed to have been paid to such Guarantor for the benefit of,
and held in trust for the benefit of, the Trustee or the Holders and shall forthwith be paid to the Trustee for the benefit of itself or such Holders to be 

  
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credited and applied to the obligations in favor of the Trustee or the Holders, as the case may be, whether matured or unmatured, in accordance with the terms of this Indenture. Each Guarantor
acknowledges that it will receive direct and indirect benefits from the financing arrangements contemplated by this Indenture and that the waiver set forth in this Section 11.05 is knowingly made in contemplation of such benefits. 

SECTION 11.06 Immediate Payment. 

Each Guarantor agrees to make immediate payment to the Trustee on behalf of the Holders of all Guarantee Obligations owing or payable to the
respective Holders upon receipt of a demand for payment therefor by the Trustee to such Guarantor in writing. 
 SECTION 11.07 No Set-Off. 

Each payment to be made by a Guarantor hereunder in respect of the Guarantee Obligations shall be payable in the currency or currencies in
which such Guarantee Obligations are denominated, and shall be made without set-off, counterclaim, reduction or diminution of any kind or nature. 

SECTION 11.08 Guarantee Obligations Absolute. 

The obligations of each Guarantor hereunder are and shall be absolute and unconditional and any monies or amounts expressed to be owing or
payable by each Guarantor hereunder which may not be recoverable from such Guarantor on the basis of a Guarantee shall be recoverable from such Guarantor as a primary obligor and principal debtor in respect thereof. 

SECTION 11.09 Guarantee Obligations Continuing. 

The obligations of each Guarantor hereunder shall be continuing and shall remain in full force and effect until all such obligations have been
paid and satisfied in full. Each Guarantor agrees with the Trustee that it will from time to time deliver to the Trustee suitable acknowledgments of this continued liability hereunder and under any other instrument or instruments in such form as
counsel to the Trustee may advise and as will prevent any action brought against it in respect of any default hereunder being barred by any statute of limitations now or hereafter in force and, in the event of the failure of a Guarantor so to do, it
hereby irrevocably appoints the Trustee the attorney and agent of such Guarantor to make, execute and deliver such written acknowledgment or acknowledgments or other instruments as may from time to time become necessary or advisable, in the
reasonable judgment of the Trustee on the advice of counsel, to fully maintain and keep in force the liability of such Guarantor hereunder. 

SECTION 11.10 Guarantee Obligations Not Reduced. 

The obligations of each Guarantor hereunder shall not be satisfied, reduced or discharged solely by the payment of such principal, interest,
fees and other monies or amounts as may at any time prior to discharge of this Indenture pursuant to Article Eight be or become owing or payable under or by virtue of or otherwise in connection with the Notes or this Indenture. 

  
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 SECTION 11.11 Guarantee Obligations Reinstated. 

The obligations of each Guarantor hereunder shall continue to be effective or shall be reinstated, as the case may be, if at any time any
payment which would otherwise have reduced the obligations of any Guarantor hereunder (whether such payment shall have been made by or on behalf of the Issuer or by or on behalf of a Guarantor) is rescinded or reclaimed from any of the Holders upon
the insolvency, bankruptcy, liquidation or reorganization of the Issuer or any Guarantor or otherwise, all as though such payment had not been made. If demand for, or acceleration of the time for, payment by the Issuer or any other Guarantor is
stayed upon the insolvency, bankruptcy, liquidation or reorganization of the Issuer or such Guarantor, all such Indebtedness otherwise subject to demand for payment or acceleration shall nonetheless be payable by each Guarantor as provided herein.

 SECTION 11.12 Guarantee Obligations Not Affected. 

The obligations of each Guarantor hereunder shall not be affected, impaired or diminished in any way by any act, omission, matter or thing
whatsoever, occurring before, upon or after any demand for payment hereunder (and whether or not known or consented to by any Guarantor or any of the Holders) which, but for this provision, might constitute a whole or partial defense to a claim
against any Guarantor hereunder or might operate to release or otherwise exonerate any Guarantor from any of its obligations hereunder or otherwise affect such obligations, whether occasioned by default of any of the Holders or otherwise, including:

 (a) any limitation of status or power, disability, incapacity or other circumstance relating to the Issuer or any other Person, including
any insolvency, bankruptcy, liquidation, reorganization, readjustment, composition, dissolution, winding-up or other proceeding involving or affecting the Issuer or any other Person; 

(b) any irregularity, defect, unenforceability or invalidity in respect of any indebtedness or other obligation of the Issuer or any other
Person under this Indenture, the Notes or any other document or instrument; 
 (c) any failure of the Issuer or any other Guarantor, whether
or not without fault on its part, to perform or comply with any of the provisions of this Indenture (including any Guarantee) or the Notes, or to give notice thereof to a Guarantor; 

(d) the taking or enforcing or exercising or the refusal or neglect to take or enforce or exercise any right or remedy from or against the
Issuer or any other Person or their respective assets or the release or discharge of any such right or remedy; 
 (e) the granting of time,
renewals, extensions, compromises, concessions, waivers, releases, discharges and other indulgences to the Issuer or any other Person; 

(f) any change in the time, manner or place of payment of, or in any other term of, any of the Notes, or any other amendment, variation,
supplement, replacement or waiver of, or any consent to departure from, any of the Notes or this Indenture, including any increase or decrease in the principal amount of or interest on any of the Notes; 

(g) any change in the ownership, control, name, objects, businesses, assets, capital structure or constitution of the Issuer or a Guarantor;

  
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 (h) any merger or amalgamation of the Issuer or a Guarantor with any Person or Persons; 

(i) the occurrence of any change in the laws, rules, regulations or ordinances of any jurisdiction by any present or future action of any
governmental authority or court amending, varying, reducing or otherwise affecting, or purporting to amend, vary, reduce or otherwise affect, any of the Guarantee Obligations or the obligations of a Guarantor under its Guarantee; and 

(j) any other circumstance that might otherwise constitute a legal or equitable discharge or defense of the Issuer under this Indenture or the
Notes or of a Guarantor in respect of its Guarantee. 
 SECTION 11.13 Waiver; Reliance. 

(a) Without in any way limiting the provisions of Section 11.01, each Guarantor hereby waives notice of acceptance hereof, notice of any
liability of any Guarantor hereunder, notice or proof of reliance by the Holders upon the obligations of any Guarantor hereunder, and diligence, presentment, demand for payment on the Issuer, protest, notice of dishonor or non-payment of any of the
Guarantee Obligations, or other notice or formalities to the Issuer or any Guarantor of any kind whatsoever. 
 (b) Each Guarantor has
independently, and without reliance on any information supplied by any Holder or the Trustee, taken whatever steps it has deemed necessary to inform itself of, and hereby assumes responsibility for taking such further steps as shall be necessary to
keep itself informed of, the financial condition and affairs of the Issuer, each other Guarantor and any other guarantor, maker or endorser of any Guarantee Obligations or any part thereof, and of all other circumstances bearing upon the risk of
nonpayment of any Guarantee Obligations or any part thereof that diligent inquiry would reveal, and each Guarantor hereby agrees that neither any Holder nor the Trustee shall have any duty to advise any Guarantor of information known to it regarding
such condition or any such circumstances. In the event any Holder or the Trustee, in its sole discretion, undertakes at any time or from time to time to provide any such information to any Guarantor, such Person shall be under no obligation to
(i) undertake any investigation not a part of its regular business routine, (ii) disclose any information that such Person, pursuant to accepted or reasonable commercial finance or banking practices, wishes to maintain confidential or
(iii) make any future disclosures of such information or any other information to such or any other Guarantor. 
 SECTION 11.14 No Obligation
To Take Action Against the Issuer. 
 Neither the Trustee nor any other Person shall have any obligation to enforce or exhaust any rights
or remedies against the Issuer or any other Person or any property of the Issuer or any other Person before the Trustee is entitled to demand payment and performance by any or all Guarantors of their liabilities and obligations under the Guarantees
or otherwise under this Indenture. 

  
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 SECTION 11.15 Dealing with the Issuer and Others. 

The Holders, without releasing, discharging, limiting or otherwise affecting in whole or in part the obligations and liabilities of any
Guarantor hereunder and without the consent of or notice to any Guarantor, may: 
 (a) grant time, renewals, extensions, compromises,
concessions, waivers, releases, discharges and other indulgences to the Issuer or any other Person; 
 (b) take or abstain from taking
security or collateral from the Issuer or from perfecting security or collateral of the Issuer; 
 (c) release, discharge, compromise,
realize, enforce or otherwise deal with or do any act or thing in respect of (with or without consideration) any and all collateral, mortgages or other security given by the Issuer or any third party with respect to the obligations or matters
contemplated by this Indenture or the Notes; 
 (d) accept compromises or arrangements from the Issuer; 

(e) apply all monies at any time received from the Issuer or from any security upon such part of the Guarantee Obligations as the Holders may
see fit or change any such application in whole or in part from time to time as the Holders may see fit; and 
 (f) otherwise deal with, or
waive or modify their right to deal with, the Issuer and all other Persons and any security as the Holders or the Trustee may see fit. 
 SECTION 11.16
Default and Enforcement. 
 If any Guarantor fails to pay in accordance with Section 11.06, the Trustee may proceed in its name
as trustee hereunder in the enforcement of the Guarantee of any such Guarantor and such Guarantor’s other obligations thereunder by any remedy provided by law, whether by legal proceedings or otherwise, and to recover from such Guarantor the
obligations. 
 SECTION 11.17 Amendment, Etc. 

Subject to Section 9.03 hereof, no amendment, modification or waiver of any provision of this Indenture relating to any Guarantor or
consent to any departure by any Guarantor or any other Person from any such provision will in any event be effective unless it is signed by such Guarantor and the Trustee. 

SECTION 11.18 Acknowledgment. 
 Each
Guarantor hereby acknowledges communication of the terms of this Indenture and the Notes and consents to and approves of the same. 

  
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 SECTION 11.19 Costs and Expenses. 

Each Guarantor shall pay on demand by the Trustee any and all costs, fees and expenses (including reasonable legal fees on a solicitor and
client basis) incurred by the Trustee, its agents, advisors and counsel or any of the Holders in enforcing any of their rights under any Guarantee. 

SECTION 11.20 No Waiver; Cumulative Remedies. 

No failure to exercise and no delay in exercising, on the part of the Trustee or the Holders, any right, remedy, power or privilege hereunder
or under this Indenture or the Notes, shall operate as a waiver thereof; nor shall any single or partial exercise of any right, remedy, power or privilege hereunder or under this Indenture or the Notes preclude any other or further exercise thereof
or the exercise of any other right, remedy, power or privilege. The rights, remedies, powers and privileges in the Guarantee and under this Indenture, the Notes and any other document or instrument between a Guarantor or the Issuer and the Trustee
are cumulative and not exclusive of any rights, remedies, powers and privilege provided by law. 
 SECTION 11.21 Survival of Guarantee
Obligations. 
 Without prejudice to the survival of any of the other obligations of each Guarantor hereunder, the obligations of each
Guarantor under Section 11.01 shall survive the payment in full of the Guarantee Obligations and shall be enforceable against such Guarantor without regard to and without giving effect to any defense, right of offset or counterclaim available
to or which may be asserted by the Issuer or any Guarantor. 
 SECTION 11.22 Guarantee in Addition to Other Guarantee Obligations. 

The obligations of each Guarantor under its Guarantee and this Indenture are in addition to and not in substitution for any other obligations
to the Trustee or to any of the Holders in relation to this Indenture or the Notes and any guarantees or security at any time held by or for the benefit of any of them. 

ARTICLE TWELVE 
 MISCELLANEOUS

 SECTION 12.01 Trust Indenture Act Controls. 

If any provision of this Indenture limits, qualifies, or conflicts with another provision which is required or deemed to be included in this
Indenture by the Trust Indenture Act, such required or deemed provision shall control. 
 SECTION 12.02 Notices. 

Any notices or other communications to the Issuer, any Guarantor or the Trustee required or permitted hereunder shall be in writing, and shall
be sufficiently given if made by hand delivery, 

  
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by nationally recognized overnight courier service, by facsimile transmission or registered or certified mail, postage prepaid, return receipt requested, addressed as follows: 

if to the Issuer or a Guarantor: 

Alere Inc. 
 51 Sawyer Road 

Waltham, Massachusetts 02453 

Attention: Chief Financial Officer 

Telephone: (781)647-3900 

Facsimile: (781) 647-3939 

With a copy to (which copy alone shall not constitute notice): 

Alere Inc. 
 51 Sawyer Road,
Suite 200 
 Waltham, Massachusetts 02453 

Attention: Ellen Chiniara, Esq., General Counsel 

Telephone: (781)647-3900 

Facsimile: (781) 647-3939 

And with a copy to (which copy alone shall not constitute notice): 

Foley Hoag LLP 
 Seaport West

 155 Seaport Boulevard 

Boston, Massachusetts 02210 

Attention: John D. Patterson, Esq. 

Telephone: (617) 832-1000 

Facsimile: (617) 832-7000 

if to the Trustee: 
 U.S. Bank
National Association 
 100 Wall Street, Suite 1600 

New York, New York 10005 

Attention: Corporate Trust Services 

Telephone: (212) 361-6184 

Facsimile: (212) 809-5459 

Each of the Issuer (both for itself and any Guarantor) and the Trustee by written notice to each other such Person may designate additional or
different addresses for notices to such Person. Any notice or communication to the Issuer, any Guarantor and the Trustee shall be deemed to have been given or made as of the date so delivered if personally delivered; when replied to; when receipt is
acknowledged, if sent by facsimile transmission during normal business hours of the recipient, or, if not sent during normal business hours of the recipient, on the Business Day after the day receipt is acknowledged; five (5) calendar days
after mailing if sent by registered or certified mail, postage prepaid (except that a notice of change of address shall not be deemed to have been given until actually received by the addressee); one (1) Business Day after deposit with a
nationally recognized overnight courier service guaranteeing overnight delivery of such notice or communication. 

  
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 Any notice or communication to a Holder required or permitted hereunder shall be mailed to the
Holder at the Holder’s address as it appears on the registration books of the Registrar. 
 Failure to mail a notice or communication
to a Holder or any defect in it shall not affect its sufficiency with respect to other Holders. If a notice or communication is mailed in the manner provided above, within the time prescribed, it is duly given, whether or not the addressee receives
it. 
 If the Issuer mails a notice or communication to Holders, it shall mail a copy to the Trustee and each Agent at the same time. 

SECTION 12.03 Communications by Holders with Other Holders. 

Holders may communicate pursuant to Trust Indenture Act § 312(b) with other Holders with respect to their rights under this Indenture
(including the Guarantees) or the Notes. The Issuer, the Trustee, the Registrar and any other Person shall have the protection of Trust Indenture Act § 312(c). 

SECTION 12.04 Certificate and Opinion as to Conditions Precedent. 

Upon any request or application by the Issuer to the Trustee to take any action under this Indenture, the Issuer shall furnish to the Trustee
at the request of the Trustee: 
 (1) an Officers’ Certificate, in form and substance reasonably satisfactory to the
Trustee, stating that all conditions precedent, if any, to be performed or effected by the Issuer, if any, provided for in this Indenture relating to the proposed action have been complied with; and 

(2) an Opinion of Counsel, in form and substance reasonably satisfactory to the Trustee, stating that, in the opinion of such
counsel, all such conditions precedent, if any, have been complied with. 
 SECTION 12.05 Statements Required in Certificate or Opinion. 

Each certificate or opinion with respect to compliance with a condition or covenant provided for in this Indenture, other than the
Officers’ Certificate required by Section 4.04 or a certificate provided pursuant to Trust Indenture Act § 314(a)(4), shall comply with the provisions of Trust Indenture Act § 314(e) and shall include: 

(1) a statement that the Person making such certificate or opinion has read such covenant or condition; 

(2) a brief statement as to the nature and scope of the examination or investigation upon which the statements or opinions
contained in such certificate or opinion are based; 

  
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 (3) a statement that, in the opinion of such Person, he has made such examination
or investigation as is necessary to enable him to express an informed opinion as to whether or not such covenant or condition has been complied with; and 

(4) a statement as to whether or not, in the opinion of each such Person, such condition or covenant has been complied with or
satisfied; 
 provided, however, that with respect to matters of fact, an Opinion of Counsel may rely on an Officers’ Certificate or
certificates of public officials. 
 SECTION 12.06 Rules by Trustee and Agents. 

The Trustee may make reasonable rules for action by or a meeting of Holders of the Notes. Any Agent may make reasonable rules and set
reasonable requirements for its functions. 
 SECTION 12.07 Legal Holidays. 

If a payment date is not a Business Day, payment may be made on the next succeeding day that is a Business Day. 

SECTION 12.08 Governing Law; Waiver of Jury Trial. 

This Indenture (including the Guarantees) and the Notes will be governed by and construed in accordance with the laws of the State of New
York, but without giving effect to applicable principles of conflicts of laws to the extent that the application of the laws of another jurisdiction would be required thereby. 

Each of the Issuer, the Guarantors and the Trustee hereby irrevocably waives, to the fullest extent permitted by applicable law, any and
all right to trial by jury in any legal proceeding arising out of or relating to this Indenture, the Notes or the transaction contemplated hereby. 

SECTION 12.09 No Adverse Interpretation of Other Agreements. 

This Indenture may not be used to interpret another indenture, loan or debt agreement of any of the Issuer or any of its Subsidiaries. Any such
indenture, loan or debt agreement may not be used to interpret this Indenture. 
 SECTION 12.10 No Recourse Against Others. 

No director, officer, employee, incorporator, stockholder, organizer, member or manager of the Issuer or any Guarantor shall have any liability for any
obligations of the Issuer under the Notes or this Indenture or of any Guarantor under its Guarantee or this Indenture or for any claim based on, in respect of, or by reason of, such obligations or their creation. Each Holder by accepting a Note
waives and releases all such liability. Such waiver and release are part of the consideration for issuance of the Notes. 

  
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 SECTION 12.11 Successors. 

All agreements of the Issuer and the Guarantors in this Indenture (including the Guarantees) and the Notes shall bind their respective
successors. All agreements of the Trustee in this Indenture shall bind its successor. 
 SECTION 12.12 Duplicate Originals. 

All parties may sign any number of copies of this Indenture. Each signed copy or counterpart shall be an original, but all of them together
shall represent the same agreement. The exchange of copies of this Indenture and of signature pages by facsimile or PDF transmission shall constitute effective execution and delivery of this Indenture as to the parties hereto and may be used in lieu
of the original Indenture for all purposes. Signatures of the parties hereto transmitted by facsimile or PDF shall be deemed to be their original signatures for all purposes. 

SECTION 12.13 Severability. 
 To the
extent permitted by applicable law, in case any one or more of the provisions in this Indenture (including the Guarantees) or in the Notes shall be held invalid, illegal or unenforceable, in any respect for any reason, the validity, legality and
enforceability of any such provision in every other respect and of the remaining provisions shall not in any way be affected or impaired thereby, it being intended that all of the provisions hereof shall be enforceable to the fullest extent
permitted by law. 
 SECTION 12.14 Force Majeure. 

In no event shall the Trustee be responsible or liable for any failure or delay in the performance of its obligations hereunder arising out of
or caused by, directly or indirectly, forces beyond its control, including strikes, work stoppages, accidents, acts of war or terrorism, civil or military disturbances, nuclear or natural catastrophes or acts of God, and interruptions, loss or
malfunctions of utilities, communications or computer (software and hardware) services; it being understood that the Trustee shall use reasonable efforts which are consistent with accepted practices in the banking industry to resume performance as
soon as practicable under the circumstances. 
 SECTION 12.15 U.S.A. Patriot Act. 

The parties hereto acknowledge that, in accordance with Section 326 of the U.S.A. Patriot Act, the Trustee, like all financial
institutions and in order to help fight the funding of terrorism and money laundering, is required to obtain, verify, and record information that identifies each person or legal entity that establishes a relationship or opens an account with the
Trustee. The parties to this Indenture agree that they will provide the Trustee with such information as it may request in order for the Trustee to satisfy the requirements of the U.S.A. Patriot Act. 

  
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 SIGNATURES 

IN WITNESS WHEREOF, the parties hereto have caused this Supplemental Indenture to be duly executed as of the date first written above. 

 

			
	ISSUER:
	
	ALERE INC., a Delaware corporation as Issuer
		
	By:		 /s/ James F. Hinrichs

	Name:		James F. Hinrichs
	Title:		Executive Vice President and Chief Financial Officer
	
	Guarantors:
	
	ALERE CONNECT, LLC
	ALERE HOLDCO, INC.
	ALERE HOME MONITORING, INC.
	ALERE INFORMATICS, INC.
	ALERE INTERNATIONAL HOLDING CORP.
	ALERE NORTH AMERICA, LLC.
	ALERE SAN DIEGO, INC.
	ALERE SCARBOROUGH, INC.
	ALERE TOXICOLOGY, INC.
	ALERE TOXICOLOGY SERVICES, INC.
	ALERE US HOLDINGS, LLC
	AMEDITECH INC.
	ATS LABORATORIES, INC.
	AVEE LABORATORIES INC.
	BIOSITE INCORPORATED
	ESCREEN, INC.
	FIRST CHECK DIAGNOSTICS, LLC
	GLOBAL ANALYTICAL DEVELOPMENT LLC
	INNOVACON, INC.
	INSTANT TECHNOLOGIES, INC.
	INVERNESS MEDICAL, LLC
	IONIAN TECHNOLOGIES, LLC
	LABORATORY SPECIALISTS OF AMERICA, INC.
	PEMBROOKE OCCUPATIONAL HEALTH, INC.
	QUALITY ASSURED SERVICES, INC.
	REDWOOD TOXICOLOGY LABORATORY, INC.
	RTL HOLDINGS, INC.
	SELFCARE TECHNOLOGY, INC.
	STANDING STONE, LLC
		
	By:		 /s/ Jay McNamara

	Name:		Jay McNamara
	Title:		Authorized Officer

  
 Alere – Supplemental
Indenture 

 
			
	TRUSTEE:
	
	 U.S. BANK NATIONAL ASSOCIATION,
 as
Trustee

		
	By:		 /s/ Gagendra Hiralal

	Name:		Gagendra Hiralal
	Title:		Vice President

  
 Alere – Supplemental
Indenture 

 EXHIBIT A 

FORM OF NOTE 
 [Insert the Global Note
Legend, if applicable pursuant to the provisions of the Indenture] 
 [Insert the Private Placement Legend, if applicable pursuant to the provisions of the
Indenture] 
 [Insert the Regulation S Legend, if applicable pursuant to the provisions of the Indenture] 

  
 A-1 

 ALERE INC. 

6.375% Senior Subordinated Notes due 2023 

CUSIP No. 
 ISIN No. 

 

					
	No.		 	    $	  

 ALERE INC., a Delaware corporation (the “Issuer”), for value received promises to pay to or
its registered assigns, the principal sum of [                    ] [or such other amount as is provided in a schedule attached hereto]1 on July 1, 2023. 
 Interest Payment Dates: January 1 and July 1. 

Record Dates: December 15 and June 15. 

Reference is made to the further provisions of this Note contained herein, which will for all purposes have the same effect as if set forth at
this place. 
 IN WITNESS WHEREOF, the Issuer has caused this Note to be signed manually or by facsimile by its duly authorized officer.

 Dated: 
  

			
	ALERE INC.,
	as Issuer
		
	By:		  

	Name:		
	Title:		

  
  

	1 	This language should be included only if the Note is issued as a Global Note. 

  
 A-2 

 [FORM OF TRUSTEE’S CERTIFICATE OF AUTHENTICATION] 

This is one of the 6.375% Senior Subordinated Notes due 2023 described in the within-mentioned Indenture. 

Dated: 
  

			
	 U.S. BANK NATIONAL ASSOCIATION, as Trustee

		
	By:		  

	Authorized Signatory

  
 A-3 

 (Reverse of Note) 

6.375% Senior Subordinated Notes due 2023 

Capitalized terms used herein shall have the meanings assigned to them in the Indenture referred to below unless otherwise indicated. 

SECTION 1. Interest. Alere Inc., a Delaware corporation (the “Issuer”), promises to pay interest on the principal
amount of this Note at 6.375% per annum from June 24, 20152 until maturity. The Issuer will pay interest semi-annually on January 1 and July 1 of each year, or if any
such day is not a Business Day, on the next succeeding Business Day (each an “Interest Payment Date”), commencing January 1, 20163. Interest on the Notes will accrue from the
most recent date to which interest has been paid or, if no interest has been paid, from June 24, 20154. The Issuer shall pay interest (including post-petition interest in any proceeding under
any Bankruptcy Law) on overdue principal and premium, if any, from time to time on demand to the extent lawful at the interest rate applicable to the Notes; it shall pay interest (including post-petition interest in any proceeding under any
Bankruptcy Law) on overdue installments of interest (without regard to any applicable grace periods) from time to time on demand at the same rate to the extent lawful. Interest will be computed on the basis of a 360-day year of twelve 30-day months.

 SECTION 2. Method of Payment. The Issuer will pay interest on the Notes to the Persons who are registered Holders of Notes at the
close of business on the December 15 or June 15 next preceding the Interest Payment Date, even if such Notes are canceled after such record date and on or before such Interest Payment Date, except as provided in Section 2.12 of the
Indenture with respect to defaulted interest. The Notes will be issued in minimum denominations of $2,000 and integral multiples of $1,000. The Issuer shall pay principal, premium, if any, and interest on the Notes in such coin or currency of the
United States of America as at the time of payment is legal tender for payment of public and private debts. Principal, premium, if any, and interest on the Notes will be payable at the office or agency of the Issuer maintained for such purpose
except that, at the option of the Issuer, the payment of interest may be made by check mailed to the Holders of the Notes at their respective addresses set forth in the register of Holders of Notes; provided, however, that for Holders
that have given wire transfer instructions to the Issuer at least ten (10) Business Days prior to the applicable payment date, the Issuer will make all payments of principal, premium, if any, and interest by wire transfer of immediately
available funds to the accounts specified by the Holders thereof. Until otherwise designated by the Issuer, the Issuer’s office or agency in New York will be the office of the Trustee maintained for such purpose. 

SECTION 3. Paying Agent and Registrar. Initially, U.S. Bank National Association, the Trustee under the Indenture, will act as
Paying Agent and Registrar. The Issuer may change any Paying Agent or Registrar without notice to any Holder. Except as provided in the Indenture, the Issuer or any of its Subsidiaries may act in any such capacity. 

 
  

	2 	Date to be used in the case of the Initial Notes; date to be revised as appropriate in the case of any Additional Notes. 

	3 	Date to be used in the case of the Initial Notes; date to be revised as appropriate in the case of any Additional Notes. 

	4 	Date to be used in the case of the Initial Notes; date to be revised as appropriate in the case of any Additional Notes. 

  
 A-4 

 SECTION 4. Indenture and Subordination. The Issuer issued the Notes under an Indenture
dated as of May 12, 2009, as amended, supplemented and modified by a Twenty-First Supplemental Indenture dated as of June 24, 2015 (as so amended, supplemented and modified, the “Indenture”), by and among the Issuer, the
Guarantors and the Trustee. The terms of the Notes include those stated in the Indenture and those made part of the Indenture by reference to the Trust Indenture Act of 1939, as amended (15 U.S. Code §§ 77aaa-77bbbb) (the “Trust
Indenture Act”). The Notes are subject to all such terms, and Holders are referred to the Indenture and the Trust Indenture Act for a statement of such terms. To the extent any provision of this Note conflicts with the express provisions of
the Indenture, the provisions of the Indenture shall govern and be controlling. The payment of the Notes will, to the extent set forth in the Indenture, be subordinated in right of payment to the prior payment in full in cash or cash equivalents of
all Senior Debt. 
 SECTION 5. Optional Redemption. Except as set forth in Section 6 and Section 7 hereof and
Section 4.06(i) of the Indenture, the Notes will not be redeemable at the Issuer’s option prior to July 1, 2018. On or after July 1, 2018, the Notes will be subject to redemption at any time (which may be more than once) at the
option of the Issuer, in whole or in part, upon not less than thirty (30) nor more than sixty (60) days’ notice (except that a notice issued in connection with a redemption referred to in Article Eight of the Indenture may be more
than sixty (60) days before such Redemption Date), at the redemption prices (expressed as percentages of principal amount) set forth below, plus accrued and unpaid interest thereon, if any, to but excluding the applicable Redemption
Date, if redeemed during the corresponding period set forth below: 
  

					
	Applicable Period	  	Redemption Price	 
	 July 1, 2018 – June 30, 2019
	  	 	104.781	% 
	 July 1, 2019 – June 30, 2020
	  	 	103.188	% 
	 July 1, 2020 – June 30, 2021
	  	 	101.594	% 
	 July 1, 2021 and thereafter
	  	 	100.000	% 

 SECTION 6. Optional Redemption with Proceeds from Equity Offerings. At any time (which may be more than
once) prior to July 1, 2018, the Issuer may redeem up to 35% of the aggregate principal amount of Notes, upon not less than thirty (30) nor more than sixty (60) days’ notice, with the net cash proceeds of one or more Qualified
Equity Offerings at a redemption price equal to 106.375% of the principal amount of the Notes to be redeemed, plus accrued and unpaid interest thereon, if any, to but excluding the applicable Redemption Date; provided, however,
that (i) at least 65% of the aggregate principal amount of Notes issued under the Indenture remains outstanding immediately after the occurrence of such redemption and (ii) such redemption shall occur within ninety (90) days of the
date of the closing of any such Qualified Equity Offering. 
 SECTION 7. Make-whole Redemption. At any time (which may be more than
once) prior to July 1, 2018, the Issuer may redeem all or a part of the Notes, upon not less than thirty (30) nor more than sixty (60) days’ notice (except that a notice issued in connection with a

  
 A-5 

 
redemption referred to in Article Eight of the Indenture may be more than sixty (60) days before such Redemption Date), at a Redemption Price equal to 100% of the principal amount (or
portion thereof) of the Notes to be redeemed plus the Applicable Premium as of, and accrued and unpaid interest, if any, to but excluding, the applicable Redemption Date. “Applicable Premium” means, with respect to the
principal amount of any Note to be redeemed pursuant to this Section 7 on any Redemption Date, the greater of: (1) 1.0% of the principal amount (or portion thereof) of such Note to be redeemed; and (2) the excess, if any, of
(a) the present value at such Redemption Date of (i) the Redemption Price of such Note (or portion of the principal amount thereof to be redeemed) at July 1, 2018, as set forth in the table in Section 5 hereof, plus
(ii) all required interest payments due on such Note (or portion of the principal amount thereof to be redeemed) through July 1, 2018 (excluding accrued but unpaid interest to such Redemption Date), computed using a discount rate equal
to the Treasury Rate as of such Redemption Date plus 50 basis points; over (b) the then outstanding principal amount (or portion thereof) of such Note to be redeemed. “Treasury Rate” means, as of any Redemption Date, the
yield to maturity as of such Redemption Date of United States Treasury securities with a constant maturity (as compiled and published in the most recent Federal Reserve Statistical Release H.15 (519) that has become publicly available at least
two (2) Business Days prior to such Redemption Date (or, if such Statistical Release is no longer published, any publicly available source of similar market data)) most nearly equal to the period from such Redemption Date to July 1, 2018;
provided, however, that if the period from such Redemption Date to July 1, 2018 is less than one year, the weekly average yield on actually traded United States Treasury securities adjusted to a constant maturity of one year will
be used. 
 SECTION 8. Notice of Redemption. Notice of redemption will be mailed by first class mail at least thirty (30) days
but not more than sixty (60) days before the applicable Redemption Date (except that a notice issued in connection with a redemption referred to in Article Eight of the Indenture may be more than sixty (60) days before such Redemption
Date) to each Holder of Notes to be redeemed at its registered address. Notes in denominations larger than $2,000 may be redeemed in part. If any Note is to be redeemed in part only, the notice of redemption that relates to such Note shall state the
portion of the principal amount thereof to be redeemed. A new Note in principal amount equal to the unredeemed portion thereof will be issued in the name of the Holder thereof upon cancellation of the original Note. On and after such Redemption Date
interest ceases to accrue on Notes or portions thereof called for redemption. 
 SECTION 9. Mandatory Redemption. The Issuer shall
not be required to make mandatory redemption or sinking fund payments with respect to the Notes. 
 SECTION 10. Repurchase at Option of
Holder. Upon the occurrence of a Change of Control, and subject to certain conditions set forth in the Indenture, the Issuer will be required to offer to purchase all of the outstanding Notes at a purchase price equal to 101% of the
principal amount thereof, plus accrued and unpaid interest, if any, thereon to the date of repurchase. 
 The Issuer is, subject to
certain conditions and exceptions set forth in the Indenture, obligated to make an offer to purchase Notes at 100% of their principal amount, plus accrued and unpaid interest, if any, thereon to the date of repurchase, with certain net cash
proceeds of certain sales or other dispositions of assets in accordance with the Indenture. 

  
 A-6 

 SECTION 11. Denominations, Transfer, Exchange. The Notes are in registered form without
coupons in minimum denominations of $2,000 and integral multiples of $1,000. The transfer of Notes may be registered and Notes may be exchanged as provided in the Indenture. The Registrar and the Trustee may require a Holder, among other things, to
furnish appropriate endorsements and transfer documents and the Issuer may require a Holder to pay any taxes and fees required by law or permitted by the Indenture. The Issuer and the Registrar are not required to transfer or exchange any Note
selected for redemption. Also, the Issuer and the Registrar are not required to transfer or exchange any Notes for a period of fifteen (15) days before a selection of Notes to be redeemed. 

SECTION 12. Persons Deemed Owners. The registered Holder of a Note may be treated as its owner for all purposes. 

SECTION 13. Amendment, Supplement and Waiver. Subject to certain exceptions, the Indenture and the Notes may be amended or supplemented
with the written consent of the Holders of at least a majority in aggregate principal amount of the Notes then outstanding, and compliance with any provision may be waived with the consent of the Holders of at least a majority in aggregate principal
amount of the Notes then outstanding. Without notice to or consent of any Holder, the parties thereto may amend or supplement the Indenture and the Notes to, among other things, cure any ambiguity, defect or inconsistency in the Indenture, provide
for uncertificated Notes in addition to or in place of certificated Notes, comply with any requirements of the SEC in connection with the qualification of the Indenture under, and otherwise comply with, the Trust Indenture Act, or make any change
that does not materially adversely affect the rights of any Holder under the Indenture or the Notes. 
 SECTION 14. Defaults and
Remedies. If an Event of Default occurs and is continuing, the Trustee or the Holders of at least twenty-five percent (25%) in principal amount of the then outstanding Notes generally may by written notice to the Issuer and the Trustee
declare all the Notes to be due and payable, whereupon the Notes shall become due and payable at the time provided in Section 6.02(a) of the Indenture. Notwithstanding the foregoing, in the case of an Event of Default arising from certain
events of bankruptcy or insolvency as set forth in the Indenture, with respect to the Issuer or any Significant Subsidiary, all outstanding Notes will become due and payable without further action or notice. Holders of the Notes may not enforce the
Indenture or the Notes except as provided in the Indenture. Subject to certain limitations, Holders of at least a majority in principal amount of the then outstanding Notes may direct the Trustee in its exercise of any trust or power. The Trustee
may withhold from Holders of the Notes notice of any continuing Default (except a Default relating to the payment of principal or interest, including an accelerated payment or the failure to make a payment on the Change of Control Payment Date or
the Net Proceeds Payment Date pursuant to a Net Proceeds Offer, or a Default in complying with the provisions of Article Five of the Indenture) if it determines in good faith that withholding notice is in their interest. The Holders of at least a
majority in aggregate principal amount of the Notes then outstanding by notice to the Trustee may on behalf of the Holders of all of the Notes waive any existing Default and its consequences under the Indenture except a continuing Default in the
payment of interest on, or the principal of, or the premium, if any, on, the Notes. 

  
 A-7 

 SECTION 15. Restrictive Covenants. The Indenture contains certain covenants that, among
other things, limit the ability of the Issuer and its Restricted Subsidiaries to make restricted payments, to incur indebtedness, to create liens, to sell assets, to permit restrictions on dividends and other payments by Restricted Subsidiaries of
the Issuer, to consolidate, merge or sell all or substantially all of its assets or to engage in transactions with affiliates. The limitations are subject to a number of important qualifications and exceptions. The Issuer must annually report to the
Trustee on compliance with such limitations and other provisions in the Indenture. 
 SECTION 16. No Recourse Against Others. No
director, officer, employee, incorporator, stockholder, member or manager of the Issuer or any Guarantor shall have any liability for any obligations of the Issuer or any Guarantor under the Indenture (including the Guarantees) or the Notes for any
claim based on, in respect of, or by reason of, such obligations or their creation. Each Holder of Notes by accepting a Note waives and releases all such liability. The waiver and release are part of the consideration for issuance of the Notes and
the Guarantees. 
 SECTION 17. Guarantees. This Note will be entitled to the benefits of certain Guarantees made for the benefit of
the Holders by the Guarantors pursuant to the Indenture. Reference is hereby made to the Indenture for a statement of the respective rights, limitations of rights, duties and obligations thereunder of the Guarantors, the Trustee and the Holders.

 SECTION 18. Trustee Dealings with the Issuer. Subject to certain terms, the Trustee under the Indenture, in its individual or any
other capacity, may become the owner or pledgee of Notes and may otherwise deal with the Issuer, its Subsidiaries or their respective Affiliates as if it were not the Trustee. 

SECTION 19. Authentication. This Note shall not be valid until authenticated by the manual signature of the Trustee or an
authenticating agent. 
 SECTION 20. Abbreviations. Customary abbreviations may be used in the name of a Holder or an assignee, such
as: TEN COM (= tenants in common), TEN ENT (= tenants by the entirety), JT TEN (= joint tenants with right of survivorship and not as tenants in common), CUST (= Custodian), and U/G/M/A (= Uniform Gifts to Minors Act). 

SECTION 21. CUSIP and ISIN Numbers. Pursuant to a recommendation promulgated by the Committee on Uniform Security Identification
Procedures, the Issuer has caused CUSIP or ISIN numbers to be printed on the Notes and the Trustee may use CUSIP or ISIN numbers in notices of redemption as a convenience to Holders. No representation is made as to the accuracy of such numbers
either as printed on the Notes or as contained in any notice of redemption and reliance may be placed only on the other identification numbers placed thereon. 

SECTION 22. Governing Law. This Note shall be governed by, and construed in accordance with, the laws of the State of New York, but
without giving effect to applicable principles of conflicts of laws to the extent that the application of the laws of another jurisdiction would be required thereby. 

The Issuer will furnish to any Holder upon written request and without charge a copy of the Indenture. 

  
 A-8 

 ASSIGNMENT FORM 

I or we assign and transfer this Note to: 
  

_______________________________________________________________________________ 
  

_______________________________________________________________________________ 
  

_______________________________________________________________________________ 

(Print or type name, address and zip code of assignee or transferee) 

(Insert Social Security or other identifying number of assignee or transferee) and irrevocably appoint agent to transfer this Note on the books of the Issuer.
The agent may substitute another to act for him. 
  

							
	Dated:                     		Signed:		  
		
					(Sign exactly as name appears on the other side of this Note)		

  

					
	 Signature Guarantee:
		  
		
			 Participant in a recognized Signature Guarantee

Medallion Program (or other signature guarantor
 program
reasonably acceptable to the Trustee)
		

 In connection with any transfer of this Note occurring prior to the date which is the date following the first anniversary of
the original date of issuance of such Note (or until an earlier transfer if (i) such Note is transferred following the six-month anniversary of the original date of issuance of such Note in accordance with this Indenture and (ii) the
Issuer has at the time of such transfer filed all required reports under Section 13 or 15(d) of the Exchange Act during the twelve-month period preceding the date of transfer), the undersigned confirms that it has not utilized any general
solicitation or general advertising in connection with the transfer and is making the transfer pursuant to one of the following: 
 [Check
One] 
  

					
	(1) 		—		to the Issuer or a subsidiary thereof; or
			
	(2) 		—		to a person who the transferor reasonably believes is a “qualified institutional buyer” pursuant to and in compliance with Rule 144A under the Securities Act; or
			
	(3) 		—		to an institutional “accredited investor” (as defined in Rule 501(a)(1), (2), (3) or (7) under the Securities Act) that has furnished to the Trustee a signed letter containing certain representations and agreements (the
form of which letter can be obtained from the Trustee); or
			
	(4) 		—		outside the United States to a non-“U.S. person” as defined in Rule 902 of Regulation S under the Securities Act in compliance with Rule 904 of Regulation S under the Securities Act; or
			
	(5) 		—		pursuant to the exemption from registration provided by Rule 144 under the Securities Act; or
			
	(6) 		—		pursuant to an effective registration statement under the Securities Act

  
 A-1 

 and unless the box below is checked, the undersigned confirms that such Note is not being transferred to an
“affiliate” of the Issuer as defined in Rule 144 under the Securities Act (an “Affiliate”): 
  

	 	 ̈	The transferee is an Affiliate of the Issuer. 

 Unless one of the foregoing items
(1) through (6) is checked, the Trustee and Registrar will refuse to register any of the Notes evidenced by this certificate in the name of any person other than the registered Holder thereof. If item (3), (4) or (5) is checked,
the Issuer or the Trustee may require, prior to registering any such transfer of the Notes, in their sole discretion, such written legal opinions, certifications (including an investment letter in the case of item (3) or (4)) and other
information as the Trustee or the Issuer has reasonably requested to confirm that such transfer is being made pursuant to an exemption from, or in a transaction not subject to, the registration requirements of the Securities Act. 

If none of the foregoing items (1) through (6) is checked, the Trustee or Registrar shall not be obligated to register this Note in
the name of any person other than the Holder hereof unless and until the conditions to any such transfer of registration set forth herein and in Section 2.16 of the Indenture shall have been satisfied. 

 

							
	Dated:                    				Signed:		  

					(Sign exactly as name appears on the other side of this Note)
			
	Signature Guarantee:		  
		
			 Participant in a recognized Signature Guarantee

Medallion Program (or other signature guarantor
 program
reasonably acceptable to the Trustee)
		

 TO BE COMPLETED BY PURCHASER IF (2) ABOVE IS CHECKED 

The undersigned represents and warrants that it is purchasing this Note for its own account or an account with respect to which it exercises sole investment
discretion and that it and any such account is a “qualified institutional buyer” within the meaning of Rule 144A under the Securities Act and is aware that the sale to it is being made in reliance on Rule 144A and acknowledges that it
has received such information regarding the Issuer as the undersigned has requested pursuant to Rule 144A or has determined not to request such information and that it is aware that the transferor is relying upon the undersigned’s foregoing
representations in order to claim the exemption from registration provided by Rule 144A. 
  

			
	Dated:                    		  

			NOTICE: To be executed by an executive officer

 OPTION OF HOLDER TO ELECT PURCHASE 

If you want to elect to have this Note purchased by the Issuer pursuant to Section 4.06 or Section 4.10 of the Indenture, check the appropriate box
below: 
  

			
	 Section 4.06
[                    ]
		 Section 4.10
[                    ]

 If you want to elect to have only part of this Note purchased by the Issuer pursuant to Section 4.06 or Section 4.10
of the Indenture, state the amount (in minimum denominations of $2,000 and integral multiples of $1,000): $         
  

							
	Dated:                    				Signed:		  

					(Sign exactly as name appears on the other side of this Note)
			
	Signature Guarantee:		  
		
			 Participant in a recognized Signature Guarantee

Medallion Program (or other signature guarantor
 program
reasonably acceptable to the Trustee)
		

 SCHEDULE OF EXCHANGES OF INTERESTS IN THE GLOBAL
NOTE5 
 The following exchanges of a part of this Global Note for an interest in another Global Note
or for a Physical Note, or exchanges of a part of another Global Note or Physical Note for an interest in this Global Note, have been made: 
  

									
	 Date of Exchange
	 	 Amount of

decrease in
 Principal Amount

of this
 Global Note
	 	 Amount of

increase in
 Principal Amount

of this
 Global Note
	 	 Principal Amount

of this
 Global Note

following such
 decrease

(or increase)
	 	 Signature of

authorized officer
 of Trustee or

Note Custodian

		 		 		 		 	
		 		 		 		 	
		 		 		 		 	

  

	5 	This schedule should be included only if the Note is issued as a Global Note. 

 EXHIBIT B 

FORMS OF LEGENDS 
 Each Global Note and
Physical Note that constitutes a Restricted Security (other than a Regulation S Global Note or a Physical Note representing Notes sold to a Non-U.S. Person in reliance on Regulation S) shall bear the following legend (the “Private Placement
Legend”) on the face thereof until the first anniversary of the original date of issuance of such Note (or until an earlier transfer if (i) such Note is transferred following the six-month anniversary of the original date of issuance
of such Note in accordance with the Indenture and (ii) the Issuer has at the time of such transfer filed all required reports under Section 13 or 15(d) of the Exchange Act during the twelve-month period preceding the date of transfer),
unless otherwise agreed by the Issuer and the Holder thereof or if such legend is no longer required by Section 2.16(e) of the Indenture: 

THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), OR THE SECURITIES LAWS OF
ANY STATE OR OTHER JURISDICTION. NEITHER THIS SECURITY NOR ANY INTEREST OR PARTICIPATION HEREIN MAY BE REOFFERED, SOLD, ASSIGNED, TRANSFERRED, PLEDGED, ENCUMBERED OR OTHERWISE DISPOSED OF IN THE ABSENCE OF SUCH REGISTRATION OR UNLESS SUCH
TRANSACTION IS EXEMPT FROM, OR NOT SUBJECT TO, SUCH REGISTRATION. THE HOLDER OF THIS SECURITY, BY ITS ACCEPTANCE HEREOF, AGREES ON ITS OWN BEHALF AND ON BEHALF OF ANY INVESTOR ACCOUNT FOR WHICH IT HAS PURCHASED SECURITIES, TO OFFER, SELL, ASSIGN,
TRANSFER, PLEDGE, ENCUMBER OR OTHERWISE DISPOSE OF SUCH SECURITY, PRIOR TO THE DATE (THE “RESALE RESTRICTION TERMINATION DATE”) THAT IS SIX MONTHS AFTER THE LATEST OF THE ORIGINAL ISSUE DATE HEREOF, THE ORIGINAL ISSUE DATE OF THE ISSUANCE
OF ANY ADDITIONAL NOTES AND THE LAST DATE ON WHICH THE ISSUER OR ANY AFFILIATE OF THE ISSUER WAS THE OWNER OF THIS SECURITY (OR ANY PREDECESSOR OF SUCH SECURITY), ONLY (A) TO THE COMPANY OR ANY SUBSIDIARY THEREOF, (B) PURSUANT TO A
REGISTRATION STATEMENT THAT HAS BEEN DECLARED EFFECTIVE UNDER THE SECURITIES ACT, (C) FOR SO LONG AS THE SECURITIES ARE ELIGIBLE FOR RESALE PURSUANT TO RULE 144A UNDER THE SECURITIES ACT (“RULE 144A”), TO A PERSON IT REASONABLY
BELIEVES IS A “QUALIFIED INSTITUTIONAL BUYER” AS DEFINED IN RULE 144A THAT PURCHASES FOR ITS OWN ACCOUNT OR FOR THE ACCOUNT OF A QUALIFIED INSTITUTIONAL BUYER TO WHOM NOTICE IS GIVEN THAT THE TRANSFER IS BEING MADE IN RELIANCE ON RULE
144A, (D) PURSUANT TO OFFERS AND SALES TO NON-U.S. PERSONS THAT OCCUR OUTSIDE THE UNITED STATES WITHIN THE MEANING OF REGULATION S UNDER THE SECURITIES ACT, (E) TO AN INSTITUTIONAL “ACCREDITED INVESTOR” WITHIN THE MEANING OF RULE
501(a)(1), (2), (3) OR (7) UNDER THE SECURITIES ACT THAT IS NOT A QUALIFIED INSTITUTIONAL BUYER AND THAT IS PURCHASING FOR ITS OWN ACCOUNT OR FOR THE ACCOUNT OF 

  
 B-1 

 
ANOTHER INSTITUTIONAL ACCREDITED INVESTOR OR (F) PURSUANT TO ANOTHER AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT, SUBJECT TO THE COMPANY’S AND THE
TRUSTEE’S RIGHT PRIOR TO ANY SUCH OFFER, SALE, ASSIGNMENT, TRANSFER, PLEDGE, ENCUMBRANCE OR OTHER DISPOSITION PURSUANT TO CLAUSES (D), (E) OR (F) TO REQUIRE THE DELIVERY OF AN OPINION OF COUNSEL, CERTIFICATION AND/ OR OTHER
INFORMATION SATISFACTORY TO EACH OF THEM. 
 Each Regulation S Global Note and each Physical Note representing Notes sold to a Non-U.S. Person in reliance
on Regulation S shall bear the following legend on the face thereof (the “Regulation S Legend”), until receipt by the Issuer and the Trustee of a certificate substantially in the form of Exhibit D hereto: 

THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), OR THE SECURITIES LAWS OF
ANY STATE OR OTHER JURISDICTION. NEITHER THIS SECURITY NOR ANY INTEREST OR PARTICIPATION HEREIN MAY BE REOFFERED, SOLD, ASSIGNED, TRANSFERRED, PLEDGED, ENCUMBERED OR OTHERWISE DISPOSED OF IN THE ABSENCE OF SUCH REGISTRATION OR UNLESS SUCH
TRANSACTION IS EXEMPT FROM, OR NOT SUBJECT TO, SUCH REGISTRATION. THE HOLDER OF THIS SECURITY, BY ITS ACCEPTANCE HEREOF, AGREES ON ITS OWN BEHALF AND ON BEHALF OF ANY INVESTOR ACCOUNT FOR WHICH IT HAS PURCHASED SECURITIES, TO OFFER, SELL, ASSIGN,
TRANSFER, PLEDGE, ENCUMBER OR OTHERWISE DISPOSE OF SUCH SECURITY, PRIOR TO THE DATE (THE “RESALE RESTRICTION TERMINATION DATE”) THAT IS 40 DAYS AFTER THE LATEST OF THE ORIGINAL ISSUE DATE HEREOF, THE ORIGINAL ISSUE DATE OF ANY ADDITIONAL
NOTES AND THE DATE ON WHICH THIS SECURITY (OR ANY PREDECESSOR OF SUCH SECURITY) WAS FIRST OFFERED TO PERSONS OTHER THAN DISTRIBUTORS (AS DEFINED IN RULE 902 OF REGULATION S) IN RELIANCE ON REGULATION S, ONLY (A) TO THE COMPANY OR ANY SUBSIDIARY
THEREOF, (B) PURSUANT TO A REGISTRATION STATEMENT THAT HAS BEEN DECLARED EFFECTIVE UNDER THE SECURITIES ACT, (C) FOR SO LONG AS THE SECURITIES ARE ELIGIBLE FOR RESALE PURSUANT TO RULE 144A UNDER THE SECURITIES ACT (“RULE 144A”),
TO A PERSON IT REASONABLY BELIEVES IS A “QUALIFIED INSTITUTIONAL BUYER” AS DEFINED IN RULE 144A THAT PURCHASES FOR ITS OWN ACCOUNT OR FOR THE ACCOUNT OF A QUALIFIED INSTITUTIONAL BUYER TO WHOM NOTICE IS GIVEN THAT THE TRANSFER IS BEING
MADE IN RELIANCE ON RULE 144A, (D) PURSUANT TO OFFERS AND SALES TO NON-U.S. PERSONS THAT OCCUR OUTSIDE THE UNITED STATES WITHIN THE MEANING OF REGULATION S UNDER THE SECURITIES ACT, (E) TO AN INSTITUTIONAL “ACCREDITED INVESTOR”
WITHIN THE MEANING OF RULE 501(a)(1), (2), (3) OR (7) UNDER THE SECURITIES ACT THAT IS NOT A QUALIFIED INSTITUTIONAL BUYER AND THAT IS PURCHASING FOR ITS OWN ACCOUNT OR FOR THE ACCOUNT OF ANOTHER INSTITUTIONAL

  
 B-2 

 
ACCREDITED INVESTOR OR (F) PURSUANT TO ANOTHER AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT, SUBJECT TO THE COMPANY’S AND THE TRUSTEE’S RIGHT PRIOR
TO ANY SUCH OFFER, SALE, ASSIGNMENT, TRANSFER, PLEDGE, ENCUMBRANCE OR OTHER DISPOSITION PURSUANT TO CLAUSES (D), (E) OR (F) TO REQUIRE THE DELIVERY OF AN OPINION OF COUNSEL, CERTIFICATION AND/ OR OTHER INFORMATION SATISFACTORY TO EACH OF
THEM. 
 BY ITS ACQUISITION HEREOF, THE HOLDER HEREOF REPRESENTS THAT IT IS NOT A U.S. PERSON NOR IS IT PURCHASING FOR THE ACCOUNT OF A U.S.
PERSON AND IS ACQUIRING THIS SECURITY IN AN OFFSHORE TRANSACTION IN ACCORDANCE WITH REGULATION S UNDER THE SECURITIES ACT. 
 Each Note shall bear the
following legend on the face thereof: 
 BY ITS ACQUISITION OF THIS SECURITY, THE HOLDER HEREOF WILL BE DEEMED TO HAVE REPRESENTED AND
WARRANTED TO THE COMPANY AND THE TRUSTEE THAT EITHER (1) NO PORTION OF THE ASSETS USED BY SUCH HOLDER TO ACQUIRE OR HOLD THIS SECURITY CONSTITUTES ASSETS OF AN EMPLOYEE BENEFIT PLAN THAT IS SUBJECT TO TITLE I OF THE U.S. EMPLOYEE RETIREMENT
INCOME SECURITY ACT OF 1974, AS AMENDED (“ERISA”), OF A PLAN, INDIVIDUAL RETIREMENT ACCOUNT OR OTHER ARRANGEMENT THAT IS SUBJECT TO SECTION 4975 OF THE U.S. INTERNAL REVENUE CODE OF 1986, AS AMENDED (THE “CODE”) OR PROVISIONS
UNDER ANY OTHER FEDERAL, STATE, LOCAL, NON-U.S. OR OTHER LAWS OR REGULATIONS THAT ARE SIMILAR TO SUCH PROVISIONS OF ERISA OR THE CODE (“SIMILAR LAWS”), OR OF AN ENTITY WHOSE UNDERLYING ASSETS ARE CONSIDERED TO INCLUDE “PLAN
ASSETS” OF ANY SUCH PLAN, ACCOUNT OR ARRANGEMENT, OR (2) THE ACQUISITION AND HOLDING OF THIS SECURITY WILL NOT CONSTITUTE A NON-EXEMPT PROHIBITED TRANSACTION UNDER SECTION 406 OF ERISA OR SECTION 4975 OF THE CODE OR A SIMILAR VIOLATION
UNDER ANY APPLICABLE SIMILAR LAWS. 
 Each Global Note authenticated and delivered hereunder shall also bear the following legend (the “Global Note
Legend”): 
 THIS NOTE IS A GLOBAL NOTE WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF
A DEPOSITORY OR A NOMINEE OF A DEPOSITORY OR A SUCCESSOR DEPOSITORY. THIS NOTE IS NOT EXCHANGEABLE FOR NOTES REGISTERED IN THE NAME OF A PERSON OTHER THAN THE DEPOSITORY OR ITS NOMINEE EXCEPT IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE,
AND NO TRANSFER OF THIS NOTE (OTHER THAN A TRANSFER OF THIS NOTE AS A WHOLE BY THE DEPOSITORY TO A NOMINEE OF THE 

  
 B-3 

 
DEPOSITORY OR BY A NOMINEE OF THE DEPOSITORY TO THE DEPOSITORY OR ANOTHER NOMINEE OF THE DEPOSITORY) MAY BE REGISTERED EXCEPT IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE. 

UNLESS THIS CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION
(“DTC”), TO THE ISSUER OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE
OF DTC (AND ANY PAYMENT IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE
REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 
 TRANSFERS OF THIS GLOBAL NOTE SHALL BE LIMITED TO TRANSFERS IN
WHOLE, BUT NOT IN PART, TO NOMINEES OF CEDE & CO. OR TO A SUCCESSOR THEREOF OR SUCH SUCCESSOR’S NOMINEE AND TRANSFERS OF PORTIONS OF THIS GLOBAL NOTE SHALL BE LIMITED TO TRANSFERS MADE IN ACCORDANCE WITH THE RESTRICTIONS SET FORTH IN
SECTION 2.16 OF THE INDENTURE. 

  
 B-4 

 EXHIBIT C 

FORM OF CERTIFICATE TO BE 

DELIVERED IN CONNECTION WITH 

TRANSFERS TO NON-QIB INSTITUTIONAL ACCREDITED INVESTORS 

U.S. Bank National Association 
 100 Wall Street, Suite 1600 

New York, New York 10005 
 Attention: Corporate Trust Services

  

	 	Re:	Alere Inc. (the “Issuer”) 

 6.375% Senior Subordinated Notes due 2023 (the
“Notes”) 
 Ladies and Gentlemen: 
 In
connection with our proposed purchase of Notes, we confirm that: 
 1. We understand that any subsequent offer, sale, assignment, transfer,
pledge, encumbrance, or other disposition of the Notes is subject to certain restrictions and conditions set forth in the Indenture relating to the Notes (the “Indenture”) and the undersigned agrees to be bound by, and not to offer,
sell, assign, transfer, pledge, encumber or otherwise dispose of the Notes except in compliance with, such restrictions and conditions and the Securities Act of 1933, as amended (the “Securities Act”), and all applicable state
securities laws. 
 2. We understand that the offer and sale of the Notes have not been registered under the Securities Act, and that the
Notes may not be offered, sold, assigned, transferred, pledged, encumbered or otherwise disposed of except as permitted in the following sentence. We agree, on our own behalf and on behalf of any accounts for which we are acting as hereinafter
stated, that if we should offer, sell, assign, transfer, pledge, encumber or otherwise dispose of any Notes, we will do so only (A) to the Issuer or any subsidiary thereof, (B) pursuant to a registration statement that has been declared
effective under the Securities Act, (C) for so long as the Notes are eligible for resale pursuant to Rule 144A under the Securities Act (“Rule 144A”), to a person we reasonably believe is a “qualified institutional buyer” as
defined in Rule 144A that purchases for its own account or for the account of a qualified institutional buyer to whom notice is given that the transfer is being made in reliance on Rule 144A, (D) pursuant to offers and sales to non-U.S. persons
that occur outside the United States within the meaning of Regulation S under the Securities Act, (D) to an institutional “accredited investor” within the meaning of Rule 501(a)(1), (2), (3) or (7) under the Securities Act
that is not a qualified institutional buyer and that is purchasing for its own account or for the account of another institutional accredited investor or (F) pursuant to another available exemption from the registration requirements of the
Securities Act, subject to the Issuer’s and the Trustee’s (as defined in the Indenture) right prior to any such offer, sale, assignment, transfer, pledge, encumbrance or other disposition pursuant

  
 C-1 

 
to clauses (D), (E) or (F) to require the delivery of an opinion of counsel, certification and/ or other information satisfactory to each of them, and we further agree to provide to any
person purchasing any of the Notes from us a notice advising such purchaser of the restrictions stated herein. 
 3. Either
(A) no portion of the assets we are using to acquire or hold the Notes constitutes assets of an employee benefit plan that is subject to Title I of the U.S. Employee Retirement Income Security Act of 1974, as amended (“ERISA”), of any
plan, account or other arrangement that is subject to Section 4975 of the U.S. Internal Revenue Code of 1986, as amended (the “Code”), or provisions under any other federal, state, local, non-U.S. or other laws or regulations that are
similar to such provisions of ERISA or the Code (“Similar Laws”), or of an entity whose underlying assets are considered to include “plan assets” of any such plan, account or arrangement, or (B) the acquisition and holding
of the Notes by us will not constitute a non-exempt prohibited transaction under Section 406 of ERISA or Section 4975 of the Code or a similar violation under any applicable Similar Law. 

4. We understand that, on any proposed offer, sale, assignment, transfer, pledge, encumbrance, or other disposition of any Notes, we will be
required to furnish to the Trustee and the Issuer such certification, legal opinions and other information as the Trustee and the Issuer may reasonably require to confirm that the proposed offer, sale, assignment, transfer, pledge, encumbrance, or
other disposition complies with the foregoing restrictions. We further understand that the Notes purchased by us will bear a legend to the foregoing effect. 

5. We are an institutional “accredited investor” (as defined in Rule 501(a)(1), (2), (3) or (7) of Regulation D under the
Securities Act) and have such knowledge and experience in financial and business matters as to be capable of evaluating the merits and risks of our investment in the Notes, and we and any accounts for which we are acting are each able to bear the
economic risk of our or their investment, as the case may be. 
 6. We are acquiring the Notes purchased by us for our account or for one or
more accounts (each of which is an institutional “accredited investor”) as to each of which we exercise sole investment discretion. 
 You, as
Trustee, the Issuer, counsel for the Issuer and others are entitled to rely upon this letter and are irrevocably authorized to produce this letter or a copy hereof to any interested party in any administrative or legal proceeding or official inquiry
with respect to the matters covered hereby. 
  

			
	Very truly yours,
	
	[Name of Transferee]
		
	By:		  

	Name:		
	Title:		

  
 C-2 

 EXHIBIT D 

FORM OF CERTIFICATE TO BE DELIVERED 

IN CONNECTION WITH TRANSFERS 

PURSUANT TO REGULATION S 
 U.S. Bank
National Association 
 100 Wall Street, Suite 1600 
 New York,
New York 10005 
 Attention: Corporate Trust Services 
  

	 	Re:	Alere Inc. (the “Issuer”) 

 6.375% Senior Subordinated Notes due 2023 (the
“Notes”) 
 Ladies and Gentlemen: 
 In
connection with our proposed sale of $[        ] aggregate principal amount of the Notes, we confirm that such sale has been effected pursuant to and in accordance with Regulation S
(“Regulation S”) under the U.S. Securities Act of 1933, as amended (the “Securities Act”), and, accordingly, we represent that: 

(1) the offer of the Notes was not made to a person in the United States; 

(2) either (a) at the time the buy offer was originated, the transferee was outside the United States or we and any person acting on our
behalf reasonably believed that the transferee was outside the United States, or (b) the transaction was executed in, on or through the facilities of a designated offshore securities market and neither we nor any person acting on our behalf
knows that the transaction has been prearranged with a buyer in the United States; 
 (3) no directed selling efforts have been made in the
United States in contravention of the requirements of Rule 903 or Rule 904 of Regulation S, as applicable; 
 (4) the transaction is not part
of a plan or scheme to evade the registration requirements of the Securities Act; and 
 (5) we have advised the transferee of the transfer
restrictions applicable to the Notes. 
 You, as Trustee, the Issuer, counsel for the Issuer and others are entitled to rely upon this letter and are
irrevocably authorized to produce this letter or a copy hereof to any interested party in any administrative or legal proceedings or official inquiry with respect to the matters covered hereby. Terms used in this certificate have the meanings set
forth in Regulation S. 

  
 D-1 

 
			
	Very truly yours,
	
	[Name of Transferor]
		
	By:		  

	Name:		
	Title:		

  
 D-2 

 EXHIBIT E 

FORM OF SUPPLEMENTAL INDENTURE 

SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of
            , 20    , among [SUBSIDIARY GUARANTOR] (the “New Guarantor”), a Subsidiary of Alere Inc. (or its successor) (the
“Issuer”), ALERE INC., a Delaware corporation, on behalf of itself and the Guarantors (the “Existing Guarantors”) under the Indenture referred to below, and U.S. BANK NATIONAL ASSOCIATION, as Trustee under the
Indenture referred to below (the “Trustee”). 
 WITNESSETH: 

WHEREAS the Issuer has heretofore executed and delivered an Indenture dated as of May 12, 2009, as amended, supplemented and modified by
a Twenty-First Supplemental Indenture dated as of June 24, 2015 (as so amended, supplemented or modified, and as further amended, supplemented or modified to date, the “Indenture”), by and among the Issuer, the Existing
Guarantors and the Trustee, providing for the issuance of 6.375% Senior Subordinated Notes due 2023 (the “Notes”); 

WHEREAS Section 4.13 of the Indenture provides that under certain circumstances the Issuer is required to cause the New Guarantor to
execute and deliver to the Trustee a supplemental indenture pursuant to which the New Guarantor shall unconditionally and irrevocably guarantee all of the Issuer’s obligations under the Notes pursuant to a guarantee on the terms and conditions
set forth herein; and 
 WHEREAS pursuant to Section 9.01 of the Indenture, the Trustee, the Issuer and the Existing Guarantors are
authorized to execute and deliver this Supplemental Indenture; 
 NOW THEREFORE, in consideration of the foregoing and for other good and
valuable consideration, the receipt of which is hereby acknowledged, the New Guarantor, the Trustee and, on behalf of itself and the Existing Guarantors, the Issuer mutually covenant and agree for the equal and ratable benefit of the Holders as
follows: 
 SECTION 1. Definitions. For all purposes of this Supplemental Indenture, except as otherwise herein expressly provided or
unless the context otherwise requires: (i) the terms and expressions used herein shall have the same meanings as corresponding terms and expressions used in the Indenture; and (ii) the words “herein,” “hereof” and
“hereby” and other words of similar import used in this Supplemental Indenture refer to this Supplemental Indenture as a whole and not to any particular section hereof. 

SECTION 2. Agreement to Guarantee. The New Guarantor hereby unconditionally and irrevocably agrees, jointly and severally with all
other Guarantors, to guarantee the Issuer’s obligations under the Notes and the Indenture on the terms and subject to the conditions set forth in Article Eleven of the Indenture and to be bound by all other applicable provisions of the
Indenture. 

  
 E-1 

 SECTION 3. Ratification of Indenture; Supplemental Indenture Part of Indenture. Except as
expressly amended hereby, the Indenture is in all respects ratified and confirmed and all the terms, conditions and provisions thereof shall remain in full force and effect. This Supplemental Indenture shall form a part of the Indenture for all
purposes, and every Holder heretofore or hereafter authenticated and delivered shall be bound hereby. 
 SECTION 4. Governing Law.
This Supplemental Indenture shall be governed by, and construed in accordance with, the laws of the State of New York, but without giving effect to applicable principles of conflicts of laws to the extent that the application of the laws of another
jurisdiction would be required thereby. 
 SECTION 5. Trustee Makes No Representation. The Trustee makes no representation as to the
validity or sufficiency of this Supplemental Indenture or as to the recitals contained herein. 
 SECTION 6. Counterparts. The
parties may sign any number of copies of this Supplemental Indenture. Each signed copy shall be an original, but all of them together represent the same agreement. 

SECTION 7. Effect of Headings. The Section headings herein are for convenience only and shall not affect the construction thereof. 

IN WITNESS WHEREOF, the parties hereto have caused this Supplemental Indenture to be duly executed as of the date first above written. 

 

			
	 [NEW SUBSIDIARY GUARANTOR], as the New Guarantor

		
	By:		  

	Name:		
	Title:		
	
	 ALERE INC., on behalf of itself and the Existing Guarantors

		
	By:		  

	Name:		
	Title:		
	
	 U.S. BANK NATIONAL ASSOCIATION, as Trustee

		
	By:		  

	Name:		
	Title:		

  
 E-2EX-10.1

 Exhibit 10.1 

EXECUTION VERSION 
 CREDIT
AGREEMENT 
 Dated as of June 18, 2015 

among 
 ALERE INC., 

as Borrower, 
 THE LENDERS AND L/C
ISSUERS PARTY HERETO, 
 GOLDMAN SACHS BANK USA, 

as B Term Loan Administrative Agent, 

GENERAL ELECTRIC CAPITAL CORPORATION, 

as Collateral Agent and Pro Rata Administrative Agent, 

GENERAL ELECTRIC CAPITAL CORPORATION, 

as Syndication Agent 
 and 

CITIZENS BANK, N.A. and DNB BANK ASA, NEW YORK BRANCH, 

as Co-Documentation Agents 
  

¿ ¿ ¿ 
 GOLDMAN SACHS BANK USA, GE CAPITAL MARKETS, INC., J.P. MORGAN SECURITIES

 LLC, DNB MARKETS, INC., RBC CAPITAL MARKETS, HSBC SECURITIES (USA) INC. and 

CITIZENS BANK, N.A., 
 as Joint Lead
Arrangers and Bookrunners 

 Table of Contents 

 

							
	 	 	 	  	Page	 
	 ARTICLE I Definitions, Interpretation and Accounting Terms
	  	 	1	  
			
	 Section 1.1
	 	 Defined Terms
	  	 	1	  
	 Section 1.2
	 	 UCC Terms
	  	 	52	  
	 Section 1.3
	 	 Accounting Terms and Principles
	  	 	52	  
	 Section 1.4
	 	 Payments
	  	 	53	  
	 Section 1.5
	 	 Interpretation
	  	 	53	  
	 Section 1.6
	 	 Available Amount Transactions
	  	 	54	  
		
	 ARTICLE II The Facilities
	  	 	54	  
			
	 Section 2.1
	 	 The Commitments
	  	 	54	  
	 Section 2.2
	 	 Borrowing Procedures
	  	 	54	  
	 Section 2.3
	 	 Swing Loans
	  	 	56	  
	 Section 2.4
	 	 Letters of Credit
	  	 	57	  
	 Section 2.5
	 	 Reduction and Termination of the Commitments
	  	 	60	  
	 Section 2.6
	 	 Repayment of Loans
	  	 	61	  
	 Section 2.7
	 	 Optional Prepayments
	  	 	63	  
	 Section 2.8
	 	 Mandatory Prepayments
	  	 	63	  
	 Section 2.9
	 	 Interest
	  	 	65	  
	 Section 2.10
	 	 Conversion and Continuation Options
	  	 	66	  
	 Section 2.11
	 	 Fees
	  	 	67	  
	 Section 2.12
	 	 Application of Payments
	  	 	68	  
	 Section 2.13
	 	 Payments and Computations
	  	 	70	  
	 Section 2.14
	 	 Evidence of Debt
	  	 	71	  
	 Section 2.15
	 	 Suspension of Eurodollar Rate Option
	  	 	73	  
	 Section 2.16
	 	 Breakage Costs; Increased Costs; Capital Requirements
	  	 	74	  
	 Section 2.17
	 	 Taxes
	  	 	75	  
	 Section 2.18
	 	 Substitution of Lenders
	  	 	79	  
	 Section 2.19
	 	 Incremental Term Loans and Incremental Revolving Credit Commitments
	  	 	80	  
	 Section 2.20
	 	 Defaulting Lenders
	  	 	85	  
	 Section 2.21
	 	 Reverse Dutch Auction Repurchases
	  	 	87	  
	 Section 2.22
	 	 Specified Refinancing Loans
	  	 	89	  
	 Section 2.23
	 	 Extensions of Term Loans; Extensions of Revolving Loans
	  	 	92	  
		
	 ARTICLE III Conditions To Loans And Letters Of Credit
	  	 	96	  
			
	 Section 3.1
	 	 Conditions Precedent to Loans and Letters of Credit on the Closing Date
	  	 	96	  
	 Section 3.2
	 	 Conditions Precedent to Each Loan and Letter of Credit
	  	 	99	  
	 Section 3.3
	 	 Determinations of Initial Borrowing Conditions
	  	 	100	  
		
	 ARTICLE IV Representations and Warranties
	  	 	100	  
			
	 Section 4.1
	 	 Corporate Existence; Compliance with Law
	  	 	100	  
	 Section 4.2
	 	 Loan Documents
	  	 	101	  
	 Section 4.3
	 	 Ownership of Group Member
	  	 	101	  
	 Section 4.4
	 	 Financial Statements
	  	 	102	  
	 Section 4.5
	 	 Material Adverse Effect
	  	 	103	  
	 Section 4.6
	 	 Solvency
	  	 	103	  
	 Section 4.7
	 	 Litigation
	  	 	103	  
	 Section 4.8
	 	 Taxes
	  	 	103	  
	 Section 4.9
	 	 Margin Regulations
	  	 	103	  

  
 i 

 Table of Contents 

 

							
	 	 	 	  	Page	 
	 Section 4.10
	 	 No Burdensome Obligations; No Defaults
	  	 	104	  
	 Section 4.11
	 	 Investment Company Act
	  	 	104	  
	 Section 4.12
	 	 Labor Matters
	  	 	104	  
	 Section 4.13
	 	 ERISA
	  	 	105	  
	 Section 4.14
	 	 Environmental Matters
	  	 	105	  
	 Section 4.15
	 	 Intellectual Property
	  	 	106	  
	 Section 4.16
	 	 Title; Real Property
	  	 	106	  
	 Section 4.17
	 	 Bank and Security Accounts
	  	 	106	  
	 Section 4.18
	 	 Insurance
	  	 	106	  
	 Section 4.19
	 	 Use of Proceeds
	  	 	106	  
	 Section 4.20
	 	 Full Disclosure
	  	 	107	  
	 Section 4.21
	 	Anti-Money Laundering Laws; Anti-Corruption Laws; Anti-Terrorism Laws; and Sanctions Laws and Regulations.	  	 	107	  
		
	 ARTICLE V Financial Covenant
	  	 	108	  
			
	 Section 5.1
	 	 Maximum Consolidated Secured Leverage Ratio
	  	 	108	  
		
	 ARTICLE VI Reporting Covenants
	  	 	108	  
			
	 Section 6.1
	 	 Financial Statements
	  	 	108	  
	 Section 6.2
	 	 Other Events
	  	 	110	  
	 Section 6.3
	 	 Copies of Notices and Reports
	  	 	110	  
	 Section 6.4
	 	 Taxes
	  	 	110	  
	 Section 6.5
	 	 Labor Matters
	  	 	110	  
	 Section 6.6
	 	 ERISA Matters
	  	 	110	  
	 Section 6.7
	 	 Environmental Matters
	  	 	111	  
	 Section 6.8
	 	 Other Information
	  	 	111	  
	 Section 6.9
	 	 Delivery of Information to Lenders
	  	 	111	  
	 Section 6.10
	 	 Annual Lender Call
	  	 	111	  
	 Section 6.11
	 	 Patriot Act
	  	 	112	  
		
	 ARTICLE VII Affirmative Covenants
	  	 	112	  
			
	 Section 7.1
	 	 Maintenance of Corporate Existence
	  	 	112	  
	 Section 7.2
	 	 Compliance with Laws, Etc.
	  	 	112	  
	 Section 7.3
	 	 Payment of Obligations
	  	 	112	  
	 Section 7.4
	 	 Maintenance of Property
	  	 	113	  
	 Section 7.5
	 	 Maintenance of Insurance
	  	 	113	  
	 Section 7.6
	 	 Keeping of Books
	  	 	113	  
	 Section 7.7
	 	 Access to Books and Property
	  	 	113	  
	 Section 7.8
	 	 Environmental
	  	 	114	  
	 Section 7.9
	 	 Use of Proceeds
	  	 	114	  
	 Section 7.10
	 	 Additional Collateral and Guaranties
	  	 	114	  
	 Section 7.11
	 	 Deposit Accounts; Securities Accounts and Cash Collateral Accounts
	  	 	116	  
	 Section 7.12
	 	 Credit Rating
	  	 	117	  
	 Section 7.13
	 	 Post-closing Deliveries
	  	 	117	  
	 Section 7.14
	 	 Margin Regulations
	  	 	117	  
	 Section 7.15
	 	 Designation of Subsidiaries
	  	 	117	  

  
 ii 

 Table of Contents 

 

							
	 	  	 	  	Page	 
	 ARTICLE VIII Negative Covenants
	  	 	119	  
			
	 Section 8.1
	  	 Indebtedness
	  	 	119	  
	 Section 8.2
	  	 Liens
	  	 	120	  
	 Section 8.3
	  	 Investments
	  	 	122	  
	 Section 8.4
	  	 Asset Sales and Stock Issuances
	  	 	124	  
	 Section 8.5
	  	 Restricted Payments
	  	 	125	  
	 Section 8.6
	  	 Payments on Junior Indebtedness
	  	 	127	  
	 Section 8.7
	  	 Fundamental Changes
	  	 	128	  
	 Section 8.8
	  	 Change in Nature of Business
	  	 	129	  
	 Section 8.9
	  	 Transactions with Affiliates
	  	 	129	  
	 Section 8.10
	  	 Third-Party Restrictions on Indebtedness, Liens, Investments or Restricted Payments
	  	 	129	  
	 Section 8.11
	  	 Modification of Certain Documents
	  	 	130	  
	 Section 8.12
	  	 Accounting Changes; Fiscal Year
	  	 	132	  
	 Section 8.13
	  	 Compliance with ERISA
	  	 	132	  
	 Section 8.14
	  	 Use of Proceeds
	  	 	132	  
		
	 ARTICLE IX Events Of Default
	  	 	132	  
			
	 Section 9.1
	  	 Definition
	  	 	132	  
	 Section 9.2
	  	 Remedies
	  	 	134	  
	 Section 9.3
	  	 Actions in Respect of Letters of Credit
	  	 	134	  
		
	 ARTICLE X The Administrative Agents
	  	 	134	  
			
	 Section 10.1
	  	 Appointment and Duties
	  	 	134	  
	 Section 10.2
	  	 Binding Effect
	  	 	136	  
	 Section 10.3
	  	 Use of Discretion
	  	 	136	  
	 Section 10.4
	  	 Delegation of Rights and Duties
	  	 	136	  
	 Section 10.5
	  	 Reliance and Liability
	  	 	137	  
	 Section 10.6
	  	 Agents Individually
	  	 	138	  
	 Section 10.7
	  	 Lender Credit Decision
	  	 	138	  
	 Section 10.8
	  	 Expenses; Indemnities
	  	 	138	  
	 Section 10.9
	  	 Resignation of Agent or L/C Issuer
	  	 	139	  
	 Section 10.10
	  	 Release of Collateral or Guarantors
	  	 	140	  
	 Section 10.11
	  	 Additional Secured Parties
	  	 	141	  
	 Section 10.12
	  	 Titles
	  	 	142	  
	 Section 10.13
	  	 Withholding Taxes
	  	 	142	  
		
	 ARTICLE XI Miscellaneous
	  	 	142	  
			
	 Section 11.1
	  	 Amendments, Waivers, Etc.
	  	 	142	  
	 Section 11.2
	  	 Assignments and Participations; Binding Effect
	  	 	145	  
	 Section 11.3
	  	 Costs and Expenses
	  	 	149	  
	 Section 11.4
	  	 Indemnities
	  	 	150	  
	 Section 11.5
	  	 Survival
	  	 	151	  
	 Section 11.6
	  	 Limitation of Liability for Certain Damages
	  	 	151	  
	 Section 11.7
	  	 Lender-Creditor Relationship
	  	 	151	  
	 Section 11.8
	  	 Right of Setoff
	  	 	152	  
	 Section 11.9
	  	 Sharing of Payments, Etc.
	  	 	152	  
	 Section 11.10
	  	 Marshaling; Payments Set Aside
	  	 	152	  
	 Section 11.11
	  	 Notices
	  	 	153	  

  
 iii 

 Table of Contents 

 

							
	 	 	 	  	Page	 
	 Section 11.12
	 	 Electronic Transmissions
	  	 	154	  
	 Section 11.13
	 	 Governing Law
	  	 	155	  
	 Section 11.14
	 	 Jurisdiction
	  	 	155	  
	 Section 11.15
	 	 Waiver of Jury Trial
	  	 	156	  
	 Section 11.16
	 	 Severability
	  	 	156	  
	 Section 11.17
	 	 Execution in Counterparts
	  	 	156	  
	 Section 11.18
	 	 Entire Agreement
	  	 	156	  
	 Section 11.19
	 	 Use of Name
	  	 	156	  
	 Section 11.20
	 	 Non-Public Information; Confidentiality
	  	 	157	  
	 Section 11.21
	 	 Patriot Act Notice
	  	 	158	  
	 Section 11.22
	 	 Senior Indebtedness
	  	 	158	  

  
 iv 

 SCHEDULES 
  

					
	 Schedule I
		 –
		 Commitments

	 Schedule II
		 –
		 Addresses for Notices

	 Schedule 1.1(a)
				 Inactive Subsidiaries

	 Schedule 2.4
		 –
		 Existing Letters of Credit

	 Schedule 2.21
		 –
		 Reverse Dutch Auction Procedures

	 Schedule 4.2
		 –
		 Consents

	 Schedule 4.3(a)
		 –
		 Ownership of each Group Member and its Subsidiaries

	 Schedule 4.3(b)
				 P&G JV Agreements

	 Schedule 4.4(b)
		 –
		 Material Liabilities or Obligations

	 Schedule 4.7
		 –
		 Litigation

	 Schedule 4.8
		 –
		 Taxes

	 Schedule 4.12
		 –
		 Labor Matters

	 Schedule 4.14
		 –
		 Environmental Matters

	 Schedule 4.15
		 –
		 Intellectual Property

	 Schedule 4.16
		 –
		 Real Property

	 Schedule 4.17
		 –
		 Bank and Security Accounts

	 Schedule 4.18
		 –
		 Insurance

	 Schedule 7.13
		 –
		 Postclosing Deliveries

	 Schedule 8.1(b)
		 –
		 Existing Indebtedness

	 Schedule 8.2
		 –
		 Existing Liens

	 Schedule 8.3
		 –
		 Existing Investments

	 Schedule 8.9
		 –
		 Transactions with Affiliates

			
					 EXHIBITS

			
	 Exhibit A
		 –
		 Form of Assignment

	 Exhibit B-1
		 –
		 Form of A Term Loan Note

	 Exhibit B-2
		 –
		 Form of B Term Loan Note

	 Exhibit B-3
		 –
		 Form of Incremental Term Loan Note

	 Exhibit B-4
		 –
		 Form of Revolving Loan Note

	 Exhibit C
		 –
		 Form of Notice of Borrowing

	 Exhibit D
		 –
		 Form of Swingline Request

	 Exhibit E
		 –
		 Form of L/C Request

	 Exhibit F
		 –
		 Form of Notice of Conversion or Continuation

	 Exhibit G
		 –
		 Form of Compliance Certificate

	 Exhibit H
		 –
		 Form of Guaranty and Security Agreement

	 Exhibit I-1
				 Form of U.S. Tax Compliance Certificate

	 Exhibit I-2
				 Form of U.S. Tax Compliance Certificate

	 Exhibit I-3
				 Form of U.S. Tax Compliance Certificate

	 Exhibit I-4
				 Form of U.S. Tax Compliance Certificate

  
 v 

 This Credit Agreement, dated as of June 18, 2015, is entered into among ALERE INC., a
Delaware corporation (the “Borrower”), the Lenders (as defined below), the L/C Issuers (as defined below), GOLDMAN SACHS BANK, USA (“Goldman”), as an administrative agent (in such capacity, and together with its
successors and permitted assigns in such capacity, the “B Term Loan Administrative Agent”), GENERAL ELECTRIC CAPITAL CORPORATION (“GE Capital”), as an administrative agent (in such capacity, and together with its
successors and permitted assigns in such capacity, the “Pro Rata Administrative Agent” and, together with the B Term Loan Administrative Agent, the “Administrative Agents”), GE CAPITAL, as collateral agent (in such
capacity, and together with its successors and permitted assigns in such capacity, the “Collateral Agent”) for the Lenders, the L/C Issuers and the other Secured Parties (as defined below),GE Capital, as syndication agent, and
Citizens Bank, N.A. and DNB Bank ASA, New York Branch, as co-documentation agents. 
 The parties hereto agree as follows: 

ARTICLE I 
 DEFINITIONS,
INTERPRETATION AND ACCOUNTING TERMS 
 Section 1.1 Defined Terms. As used in this Agreement, the following terms have the
following meanings: 
 “A Term Loan” has the meaning specified in Section 2.1(b)(i). 

“A Term Loan Commitment” means, with respect to each Term Loan Lender, the commitment of such Lender to make A Term Loans to
the Borrower, which commitment is in the amount set forth opposite such Lender’s name on Schedule I under the caption “A Term Loan Commitment”, as amended to reflect Assignments and as such amount may be reduced pursuant
to this Agreement. The aggregate amount of the A Term Loan Commitments on the Closing Date equals $650,000,000. 
 “Administrative
Agents” has the meaning specified in the preamble hereto. 
 “Affected Lender” has the meaning specified in
Section 2.18(a). 
 “Affiliate” means, with respect to any Person, each officer, director, general partner or
joint-venturer of such Person and any other Person that directly or indirectly controls, is controlled by, or is under common control with, such Person; provided, however, that no Secured Party shall be an Affiliate of the Borrower.
For purpose of this definition, “control” means the possession of either (a) the power to vote, or the beneficial ownership of, 10% or more of the Voting Stock of such Person or (b) the power to direct or cause the
direction of the management and policies of such Person, whether by contract or otherwise. 
 “Agents” means the B Term
Loan Administrative Agent, the Pro Rata Administrative Agent and the Collateral Agent; and “Agent” means any of them, as the context may require. 

“Agreement” means this Credit Agreement. 

“Anti-Corruption Laws” means all laws, rules and regulations of any jurisdiction applicable to the Borrower or any other
Group Member from time to time concerning or relating to bribery or corruption (including the Foreign Corrupt Practices Act of 1977, as amended) administered or enforced by any Governmental Authority having jurisdiction over the Borrower or any
Group Member. 

 “Anti-Money Laundering Laws” means all applicable money laundering statutes and
related financial recordkeeping and reporting requirements and the rules and regulations thereunder and any related or similar rules, regulations or guidelines, which in each case are issued, administered or enforced by any Governmental Authority
having jurisdiction over the Borrower or any other Group Member, or to which the Borrower or any other Group Member is subject. 

“Anti-Terrorism Laws” means all laws, rules and regulations of any jurisdiction applicable to the Borrower or any other
Group Member from time to time concerning or relating to terrorism, including the Executive Order, the Trading with the Enemy Act (50 U.S.C. § 5 et seq.) and the Patriot Act. 

“Applicable Administrative Agent” means (i) in respect of any A Term Loans, any Revolving Loans (including any Extended
Revolving Loans or revolving loans in respect of any Incremental Revolving Credit Commitments or any Specified Refinancing Revolving Credit Commitments), any Swing Loans, any Extended Term Loans or Specified Refinancing Term Loans in either
case in respect of any then outstanding A Term Loans, any Letters of Credit and any Commitments in respect of any of the foregoing extensions of credit referred to in this clause (i), the Pro Rata Administrative Agent, and (ii) in respect
of any B Term Loans, any Incremental Term Loans, any Extended Term Loans or Specified Refinancing Term Loans in either case in respect of any then outstanding B Term Loans or Incremental Term Loans and any Commitments in respect of any of the
foregoing extensions of credit referred to in this clause (ii), the B Term Loan Administrative Agent. 
 “Applicable
Margin” means (x) with respect to any A Term Loan that is (i) a Base Rate Loan, 2.00% per annum, and (ii) a Eurodollar Rate Loan, 3.00% per annum, (y) with respect to any Revolving Loan and Swing Loan that is
(i) a Base Rate Loan, 2.00% per annum, and (ii) a Eurodollar Rate Loan, 3.00% per annum and (z) with respect to any B Term Loan, a percentage equal to (i) during the period commencing on the Closing Date and ending on
the next date of determination after the Closing Date, the respective percentage set forth in the applicable column opposite Level I in the table set forth below and (ii) thereafter, as of each date of determination (and until the next such
date of determination), a percentage equal to the percentage set forth below in the applicable column opposite the Level corresponding to the Consolidated Secured Leverage Ratio in effect as of the last day of the most recently ended Fiscal Quarter:

  

											
	 LEVEL
	  	 CONSOLIDATED SECURED

LEVERAGE RATIO
	  	B TERM LOANS	 
	  	  	BASE RATE LOANS	 	 	EURODOLLAR RATE LOANS
(EXCEPT FOR SWING LOANS)	 
	I	  	Greater than 2.25: 1.00	  	 	2.25	% 	 	 	3.25	% 
	II	  	Less than or equal to 2.25: 1.00	  	 	2.00	% 	 	 	3.00	% 

 Each date of determination for the “Applicable Margin” applicable to the B Term Loans shall
be the date that is 3 Business Days after delivery by the Borrower to the B Term Loan Administrative Agent of a new Compliance Certificate pursuant to Section 6.1(c). Notwithstanding anything to the contrary set forth in this Agreement
(including the then effective Consolidated Secured Leverage Ratio), the Applicable Margin with respect to B Term Loans shall equal the percentage set forth in the appropriate column opposite Level I in the table above,

  
 2 

 
effective immediately upon (x) the occurrence of any Event of Default under Section 9.1(e)(ii) or (y) the delivery of a notice by the B Term Loan Administrative Agent or the
Required B Term Loan Lenders to the Borrower during the continuance of any other Event of Default and, in each case, for as long as such Event of Default shall be continuing. 

“Applicable Threshold Price” has the meaning specified in Schedule 2.21. 

“Approved Fund” means, with respect to any Lender, any Person (other than a natural Person) that (a) is or will be
engaged in making, purchasing, holding or otherwise investing in commercial loans and similar extensions of credit in the ordinary course of its business and (b) is advised or managed by (i) such Lender, (ii) any Affiliate of such
Lender or (iii) any Person (other than an individual) or any Affiliate of any Person (other than an individual) that administers or manages such Lender. 

“Arrangers” means Goldman, GE Capital Markets, Inc., J.P. Morgan Securities LLC, DNB Markets, Inc., RBC Capital Markets, HSBC
Securities (USA) Inc. and Citizens Bank, N.A. 
 “Assignment” means an assignment agreement entered into by a Lender, as
assignor, and any Person, as assignee, pursuant to the terms and provisions of Section 11.2 (with the consent of any party whose consent is required by Section 11.2), accepted by the Applicable Administrative Agent in
substantially the form of Exhibit A, or any other form approved by the Applicable Administrative Agent. 

“Auction” has the meaning specified in Section 2.21(a). 

“Auction Manager” has the meaning specified in Section 2.21(a). 

“Auction Notice” has the meaning specified in Schedule 2.21. 

“Available Amount” means, as of any date, an amount (which shall not be less than zero), determined on a cumulative basis,
equal to, without duplication: 
 (a) the Retained Excess Cash Flow Amount, minus 

(b) the cumulative amount of Investments made in reliance on Section 8.3(m), minus 

(c) the cumulative amount of Restricted Payments made in reliance on Section 8.5(h), minus 

(d) the cumulative amount of Restricted Debt Payments made in reliance on Section 8.6(f). 

“B Term Loan” has the meaning specified in Section 2.1(b)(ii). 

“B Term Loan Administrative Agent” has the meaning specified in the preamble hereto. 

“B Term Loan Commitment” means, with respect to each Term Loan Lender, the commitment of such Lender to make B Term Loans to
the Borrower, which commitment is in the amount set forth opposite such Lender’s name on Schedule I under the caption “B Term Loan  

  
 3 

 
Commitment”, as amended to reflect Assignments and as such amount may be reduced pursuant to this Agreement. The aggregate amount of the B Term Loan Commitments on the Closing Date
equals $1,050,000,000. 
 “Base Rate” means, at any time, a rate per annum equal to the highest of (a) the rate last
quoted by The Wall Street Journal as the latest “U.S. prime rate” or, if The Wall Street Journal ceases to quote such rate, the highest per annum interest rate published by the Federal Reserve Board in Federal Reserve Statistical Release
H.15 (519) (Selected Interest Rates) as the “bank prime loan” rate or, if such rate is no longer quoted therein, any similar rate quoted therein (as determined by the Applicable Administrative Agent) or any similar release by the
Federal Reserve Board (as determined by the Applicable Administrative Agent), (b) the sum of 0.5% per annum and the Federal Funds Rate and (c) the Eurodollar Rate for a Eurodollar Rate Loan with a
one-month Interest Period commencing on such day plus 1.00%; provided that if the Base Rate shall be less than zero, such rate shall be deemed to be zero for purposes of this Agreement.
Notwithstanding the foregoing, in no event shall the Base Rate with respect to any outstanding B Term Loans be less than 2.00% per annum. 

“BBI Sale” means the Sale of (x) all of the Stock and Stock Equivalents of, or (y) any or all of the assets of, BBI
Diagnostics Group, plc and any of its Subsidiaries or any direct or indirect holding company thereof holding, directly or indirectly, the Stock and Stock Equivalents of BBI Diagnostics Group, plc and its Subsidiaries (provided that such
holding company does not engage in any material business or own any material assets other than owning, directly or indirectly, the Stock and Stock Equivalents of BBI Diagnostics Group, plc and its Subsidiaries). 

“Base Rate Loan” means any Loan that bears interest based on the Base Rate. 

“Benefit Plan” means any employee benefit plan as defined in Section 3(3) of ERISA (whether governed by the laws of the
United States or otherwise) to which any Group Member incurs or otherwise has any obligation or liability, contingent or otherwise. 

“Borrower” has the meaning specified in the preamble hereto. 

“Borrower Materials” has the meaning specified in Section 11.20(a). 

“Borrowing” means a borrowing of one Type of Loans of a single Tranche (other than Swing Loans and Loans deemed made pursuant
to Section 2.3 or 2.4) made in one Facility on the same day by the Lenders according to their respective Commitments under such Facility. 

“Business Day” means any day of the year that is not a Saturday, Sunday or a day on which banks are required or authorized to
close in New York City and, when determined in connection with notices and determinations in respect of any Eurodollar Rate or Eurodollar Rate Loan or any funding, conversion, continuation, Interest Period or payment of any Eurodollar Rate Loan,
that is also a day on which dealings in Dollar deposits are carried on in the London interbank market. 
 “Capital
Expenditures” means, for any Person for any period, the aggregate of all expenditures, whether or not made through the incurrence of Indebtedness, by such Person and its Subsidiaries during such period for the acquisition, leasing (pursuant
to a Capital Lease), construction, replacement, repair, substitution or improvement of fixed or capital assets or additions to equipment, in each case required to be capitalized under GAAP on a Consolidated

  
 4 

 
balance sheet of such Person, excluding (a) interest capitalized during construction and (b) any expenditure to the extent, for the purposes of the definition of Permitted Acquisition,
such expenditure is part of the aggregate amounts payable in connection with, or other consideration for, any Permitted Acquisition consummated during or prior to such period. 

“Capital Lease” means, with respect to any Person, any lease of, or other arrangement conveying the right to use, any
property (whether real, personal or mixed) by such Person as lessee that has been or should be accounted for as a capital lease on a balance sheet of such Person prepared in accordance with GAAP. 

“Capitalized Lease Obligations” means, at any time, with respect to any Capital Lease, any lease entered into as part of any
Sale and Leaseback Transaction of any Person or any synthetic lease, the amount of all obligations of such Person that is (or that would be, if such synthetic lease or other lease were accounted for as a Capital Lease) capitalized on a balance sheet
of such Person prepared in accordance with GAAP. 
 “Cash Collateral Account” means a deposit account or securities account
in the name of a Loan Party and under the sole control (as defined in the applicable UCC) of the Collateral Agent and (a) in the case of a deposit account, from which such Loan Party may not make withdrawals except as permitted by the
Collateral Agent and (b) in the case of a securities account, with respect to which the Collateral Agent shall be the entitlement holder and the only Person authorized to give entitlement orders with respect thereto. 

“Cash Equivalents” means (a) any readily-marketable securities (i) issued by, or directly, unconditionally and
fully guaranteed or insured by the United States federal government or (ii) issued by any agency of the United States federal government the obligations of which are fully backed by the full faith and credit of the United States federal
government, (b) any readily-marketable direct obligations issued by any other agency of the United States federal government, any state of the United States or any political subdivision of any such state or any public instrumentality thereof,
in each case having a rating of at least “A-1” from S&P or at least “P-1” from Moody’s, (c) any commercial paper rated at least “A-1” by S&P or “P-1” by Moody’s and issued
by any Person organized under the laws of any state of the United States, (d) any Dollar-denominated time deposit, insured certificate of deposit, overnight bank deposit or bankers’ acceptance issued or accepted by (i) any Lender or
(ii) any commercial bank that is (A) organized under the laws of the United States, any state thereof or the District of Columbia, (B) “adequately capitalized” (as defined in the regulations of its primary federal banking
regulators) and (C) has Tier 1 capital (as defined in such regulations) in excess of $250,000,000, (e) shares of any United States money market fund that (i) has substantially all of its assets invested continuously in the types of
investments referred to in clause (a), (b), (c) or (d) above with maturities as set forth in the proviso below, (ii) has net assets in excess of $500,000,000 and (iii) has obtained from either S&P
or Moody’s the highest rating obtainable for money market funds in the United States; provided, however, that the maturities of all obligations specified in any of clauses (a), (b), (c) and
(d) above shall not exceed 365 days, and (f) in the case of any Subsidiary organized in a jurisdiction outside the United States: (i) direct obligations of the sovereign nation (or agency thereof) in which such Subsidiary is
organized and is conducting business or in obligations fully and unconditionally guaranteed by such sovereign nation (or any agency thereof), (ii) investments of the type and maturity described in clauses (a) through
(e) above of foreign obligors, which investments or obligors (or the parents of such obligors) have ratings described in such clauses or equivalent ratings from comparable foreign rating agencies or (iii) investments of the type and
maturity described in clauses (a) through (e) above of foreign obligors (or the parents of such 

  
 5 

 
obligors), which investments or obligors (or the parent of such obligors) are not rated as provided in such clauses or in clause (ii) above but which are, in the reasonable
judgment of the Borrower, comparable in investment quality to such investments and obligors (or the parents of such obligors). 

“CERCLA” means the United States Comprehensive Environmental Response, Compensation, and Liability Act (42 U.S.C.
§§ 9601 et seq.). 
 “Change of Control” means the occurrence of any of the following: (a) any person
or group of persons (within the meaning of the Securities Exchange Act of 1934) shall have acquired beneficial ownership (within the meaning of Rule 13d-3 promulgated by the SEC under the Securities Exchange Act of 1934) of more than 50% of the
issued and outstanding shares of capital Stock of the Borrower having the right to vote for the election of directors of the Borrower under ordinary circumstances; or (b) during any period of twelve consecutive calendar months, individuals who
at the beginning of such period constituted the board of directors of the Borrower (together with any new directors whose election by the board of directors of the Borrower or whose nomination for election by the stockholders of the Borrower was
prior to such election approved or ratified by a vote of at least a majority of the directors then still in office who either were directors at the beginning of such period or whose election or nomination for election was previously so approved)
cease for any reason other than death or disability to constitute a majority of the directors then in office; or (c) a “Change of Control”, a “Fundamental Change” or “Termination of Trading” or any term of similar
effect, as defined in any Existing Notes Indenture (including in any documents relating to any Permitted Refinancing of any Existing Notes) or any Permitted Additional Debt Documents relating to Indebtedness in an aggregate principal amount equal to
or greater than $50,000,000 (or any indenture or agreement governing any Indebtedness (in an aggregate principal amount equal to or greater than $50,000,000) incurred pursuant to a Permitted Refinancing in respect of any such Indebtedness as
permitted by Section 8.1) shall occur and, as a result thereof, the Company or any Subsidiary thereof shall be required to repurchase, repay, redeem or make any similar payment or payments in respect of any such Indebtedness in an
aggregate principal amount equal to or greater than such amount. 
 “Closing Date” means the first date on which any Loan
is made or any Letter of Credit is Issued. 
 “Code” means the U.S. Internal Revenue Code of 1986, as amended from time to
time, and any regulations promulgated thereunder. 
 “Collateral” means all property and interests in property and proceeds
thereof now owned or hereafter acquired by any Loan Party in or upon which a Lien is granted or purported to be granted pursuant to any Loan Document. 

“Collateral Agent” has the meaning specified in the preamble hereto. 

“Commitment” means any of the commitments of any Lender, i.e., an A Term Loan Commitment, a B Term Loan Commitment, an
Incremental Term Loan Commitment, a Revolving Credit Commitment (including as the same may be increased through an Incremental Revolving Credit Commitment), an Extended Term Loan Commitment, an Extended Revolving Credit Commitment, a Specified
Refinancing Term Loan Commitment or a Specified Refinancing Revolving Credit Commitment. 

  
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 “Commodity Exchange Act” means the Commodity Exchange Act (7 U.S.C. § 1 et
seq.). 
 “Compliance Certificate” means a certificate substantially in the form of Exhibit G. 

“Consolidated” means, with respect to any Person, the accounts of such Person and its Subsidiaries consolidated in accordance
with GAAP. 
 “Consolidated Cash Interest Expense” means, with respect to the Borrower and its Subsidiaries for any period,
the Consolidated Interest Expense for such period less the sum of (without duplication), in each case to the extent included in the definition of Consolidated Interest Expense, (a) the amortized amount of debt discount and debt issuance
costs, (b) charges relating to write-ups or write-downs in the book or carrying value of existing Consolidated Total Debt, (c) interest payable in evidences of Indebtedness or by addition to the principal of the related Indebtedness and
(d) other non-cash interest. 
 “Consolidated Current Assets” means, with respect to the Borrower and its Subsidiaries
at any date of determination, the total Consolidated current assets of the Borrower and its Subsidiaries at such date other than cash, Cash Equivalents and any Indebtedness owing to the Borrower or any of its Subsidiaries by Affiliates of the
Borrower. 
 “Consolidated Current Liabilities” means, with respect to the Borrower and its Subsidiaries at any date of
determination, all liabilities of the Borrower and its Subsidiaries at such date that should be classified as current liabilities on a Consolidated balance sheet of the Borrower; provided, however, that “Consolidated Current
Liabilities” shall exclude the principal amount of the Loans then outstanding and the current portion of any other long-term Indebtedness that would otherwise be included therein. 

“Consolidated EBITDA” means, with respect to the Borrower and its Subsidiaries for any period, (a) the Consolidated Net
Income of the Borrower and its Subsidiaries on a Consolidated basis for such period plus (b) the sum of, in each case to the extent included in the calculation of such Consolidated Net Income but without duplication, (i) any
provision for income taxes or other taxes measured by net income, (ii) Consolidated Interest Expense, amortization of debt discount and commissions and other fees and charges associated with Indebtedness, (iii) any loss from extraordinary
items and any non-recurring loss, (iv) any depreciation, depletion and amortization expense, (v) any aggregate net loss on the Sale of property (other than accounts (as defined under the applicable UCC) and inventory) outside the ordinary
course of business, and (vi) any other non-cash expenditure, charge or loss for such period (other than any non-cash expenditure, charge or loss relating to write-offs, write-downs or reserves with respect to accounts and inventory), including
the amount of any compensation deduction as the result of any grant of Stock or Stock Equivalents to employees, officers, directors or consultants, and minus (c) the sum of, in each case to the extent included in the calculation of such
Consolidated Net Income (except, in the case of succeeding clause (v), whether or not included in such calculation) but without duplication, (i) any credit for income taxes or other taxes measured by net income, (ii) any gain from
extraordinary items and any non-recurring gain, (iii) any aggregate net gain from the Sale of property (other than accounts (as defined in the applicable UCC) and inventory) outside the ordinary course of business by such Person, (iv) any
other non-cash gain or non-cash income, including any reversal of a charge referred to in clause (b)(vi) above by reason of a decrease in the value of any Stock or Stock Equivalent and any cancellation of indebtedness income and (v) any
other cash payment in respect of expenditures, charges and losses that have been added to Consolidated EBITDA pursuant to clause (b)(vi) above in any prior period. 

  
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 “Consolidated Interest Expense” means, for the Borrower and its Subsidiaries on
a Consolidated basis for any period, total interest expense for such period and including, in any event, (i) interest capitalized during such period and net costs under Interest Rate Contracts for such period and (ii) all fees, charges,
commissions, discounts and other similar obligations (other than reimbursement obligations) with respect to letters of credit, bank guarantees, banker’s acceptances, surety bonds and performance bonds (whether or not matured) payable by the
Borrower and its Subsidiaries during such period. 
 “Consolidated Net Income” means, with respect to the Borrower and its
Subsidiaries for any period, the Consolidated net income (or loss) of the Borrower and its Subsidiaries for such period; provided, however, that the following shall be excluded: (a) the net income of any other Person in which
the Borrower or one of its Subsidiaries has a joint interest with a third-party (which interest does not cause the net income of such other Person to be Consolidated into the net income of such Person), except to the extent of the amount of
cash dividends or cash distributions paid to such Person or Subsidiary, (b) the net income of any Subsidiary that is, on the last day of such period, subject to any restriction or limitation on the payment of dividends or the making of other
distributions (other than under the Loan Documents), to the extent of such restriction or limitation, (c) the net income of any other Person arising prior to such other Person becoming a Subsidiary or merging or consolidating into the Borrower
or one of its Subsidiaries, (d) consolidated minority interest expense of such Person or one of its Subsidiaries resulting from allocations of earnings of any Consolidated Subsidiary which is less than 100% owned, except to the extent
of the amount of cash dividends and cash distributions paid by such Person or such Subsidiary to the minority shareholders of such Consolidated Subsidiary and (e) the net income of any Unrestricted Subsidiary except to the extent of the
amount of cash dividends or cash distributions paid by such Unrestricted Subsidiary to the Borrower or, subject to the foregoing clauses of this definition, a Subsidiary thereof. 

“Consolidated Secured Indebtedness” means, at any date of determination, an amount equal to the Consolidated Total Debt at
such time that is secured by a Lien on any asset of the Borrower and/or any of its Subsidiaries (including, without limitation, the Obligations) other than property or assets held in a defeasance or similar trust or arrangement for the benefit of
the Indebtedness secured thereby. 
 “Consolidated Secured Leverage Ratio” means, at any date of determination, the ratio
of (a) Consolidated Secured Indebtedness outstanding as of such date to (b) Consolidated EBITDA for the last period of four consecutive Fiscal Quarters ending on or before such date. 

“Consolidated Total Debt” means, at any date of determination, the remainder of (A) the sum of (without duplication) all
Indebtedness (or, if issued at a discount, the face amount of such Indebtedness) of a type described in clause (a), (b), (c)(i), (d), (f) or (g) of the definition thereof and all Guaranty
Obligations with respect to any such Indebtedness, in each case of the Borrower and its Subsidiaries on a Consolidated basis minus (B) the aggregate amount of all Unrestricted cash and Cash Equivalents on hand of the Loan Parties at such
time; provided that, notwithstanding anything to the contrary contained above in this definition, for purposes of calculating the Consolidated Total Leverage Ratio and the Consolidated Secured Leverage Ratio pursuant to
Section 2.19(a)(v) or clause (i) of the definition of Permitted Additional Debt (and only for such purposes), the cash proceeds of any Incremental Term Loan Facility, any Incremental Revolving Credit Commitments (or any
Revolving Loans made pursuant thereto) or any Permitted Additional Debt, as the case may be, shall not be included in the amount of Unrestricted cash and Cash Equivalents on hand of the Loans Parties at such time to be netted in the determination of
Consolidated Total Debt and Consolidated Secured Indebtedness, as applicable, in calculating either such ratio for either such purpose. 

  
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 “Consolidated Total Leverage Ratio” means, at any date of determination, the
ratio of (a) Consolidated Total Debt outstanding as of such date to (b) Consolidated EBITDA for the last period of four consecutive Fiscal Quarters ending on or before such date. 

“Constituent Documents” means, with respect to any Person, collectively and, in each case, together with any modification of
any term thereof, (a) the articles of incorporation, certificate of incorporation, constitution or certificate of formation of such Person, (b) the bylaws, operating agreement or joint venture agreement of such Person, (c) any other
constitutive, organizational or governing document of such Person, whether or not equivalent, and (d) any other document setting forth the manner of election or duties of the directors, officers or managing members of such Person or the
designation, amount or relative rights, limitations and preferences of any Stock of such Person. 
 “Contractual
Obligation” means, with respect to any Person, any provision of any Security issued by such Person or of any document or undertaking (other than a Loan Document) to which such Person is a party or by which it or any of its property
is bound or to which any of its property is subject. 
 “Control Agreement” means, with respect to any deposit account, any
securities account, commodity account, securities entitlement or commodity contract, an agreement, in form and substance satisfactory to the Collateral Agent, among the Collateral Agent, the financial institution or other Person at which such
account is maintained or with which such entitlement or contract is carried and the Loan Party maintaining such account, entitlement or contract, effective to grant “control” (as defined under the applicable UCC) over such account,
entitlement or contract, to the Collateral Agent. 
 “Controlled Deposit Account” means each deposit account (including all
funds on deposit therein) that is the subject of an effective Control Agreement and that is maintained by any Loan Party with a financial institution approved by the Collateral Agent (such approval not to be unreasonably withheld). 

“Controlled Securities Account” means each securities account or commodity account (including all financial assets
held therein and all certificates and instruments, if any, representing or evidencing such financial assets) that is the subject of an effective Control Agreement and that is maintained by any Loan Party with a securities intermediary or
commodity intermediary approved by the Collateral Agent (such approval not to be unreasonably withheld). 
 “Copyrights”
means all right, title and interest (and all related IP Ancillary Rights) arising under any Requirement of Law in or relating to copyrights and all mask work, database and design rights, whether or not registered or published, all
registrations thereof and all applications therefor. 
 “Corporate Chart” means a document in form reasonably acceptable to
the Administrative Agents and setting forth, as of a date set forth therein, for each Person that is a Loan Party, that is subject to Section 7.10, that is a Subsidiary or joint venture of any of them or that is an Unrestricted
Subsidiary, (a) the full legal name of such Person, (b) the jurisdiction of organization and, in the case of any Loan Party, any organizational number and tax identification 

  
 9 

 
number of such Person, (c) in the case of any Loan Party, the location of such Person’s chief executive office (or, if applicable, sole place of business) and (d) the percentage of
outstanding shares of each class of Stock of such Person (other than the Borrower) owned, directly or indirectly, by any Loan Party or any Subsidiary of any of them. 

“Corrective Extension Amendment” has the meaning specified in Section 2.23(f). 

“Customary Permitted Liens” means, with respect to any Person, any of the following: 

(a) Liens (i) with respect to the payment of taxes, assessments or other governmental charges or (ii) of suppliers, carriers,
materialmen, warehousemen, workmen or mechanics and other similar Liens, in each case imposed by law or arising in the ordinary course of business, and, for each of the Liens in clauses (i) and (ii) above, for amounts that
are not yet due or that are being contested in good faith by appropriate proceedings diligently conducted and with respect to which adequate reserves or other appropriate provisions are maintained on the books of such Person in accordance with GAAP;

 (b) (i) Liens of a collection bank on items in the course of collection arising under Section 4-208 of the UCC as in effect in
the State of New York or any similar section under any applicable UCC or any similar Requirement of Law of any foreign jurisdiction or (ii) other rights of setoff or banker’s liens in favor of banks or other depository institutions arising
in the ordinary course of business; 
 (c) pledges or cash deposits made in the ordinary course of business (i) in connection with
workers’ compensation, unemployment insurance, social security or other types of governmental insurance benefits (other than any Lien imposed by ERISA), (ii) to secure the performance of bids, tenders, leases (other than Capital Leases),
sales or other trade contracts (other than for the repayment of borrowed money) or (iii) made in lieu of, or to secure the performance of, surety, customs, reclamation or performance bonds (in each case not related to judgments or litigation);

 (d) judgment liens (other than for the payment of taxes, assessments or other governmental charges) securing judgments and other
proceedings not constituting an Event of Default under Section 9.1(f) and pledges or cash deposits made in lieu of, or to secure the performance of, judgment or appeal bonds in respect of such judgments and proceedings; 

(e) Liens (i) arising by reason of zoning restrictions, easements, licenses, reservations, restrictions, covenants, rights-of-way,
encroachments, minor defects or irregularities in title (including leasehold title) and other similar encumbrances on the use of real property or (ii) consisting of leases, licenses or subleases (other than Capital Leases) granted by a lessor,
licensor or sublessor on its real property in the ordinary course of business that, for each of the Liens in clauses (i) and (ii) above, do not, in the aggregate, materially (x) impair the use or occupancy of such real
property or (y) interfere with the ordinary conduct of the business conducted by the Borrower and its Subsidiaries at such real property; 

(f) Liens of landlords and mortgagees of landlords (i) arising by statute or under any lease or related Contractual Obligation entered
into in the ordinary course of business, (ii) on fixtures and movable tangible property located on the real property leased or subleased from such landlord, (iii) for amounts not overdue or that are being contested in good faith by
appropriate proceedings diligently conducted and (iv) for which adequate reserves or other appropriate provisions are maintained on the books of such Person in accordance with GAAP; 

  
 10 

 (g) the title and interest of a lessor or sublessor in and to personal property leased or
subleased (other than through a Capital Lease), in each case extending only to such personal property; 
 (h) licenses and sublicenses of
intellectual property granted to third parties in the ordinary course of business that do not, in the aggregate, materially (x) impair the use of such intellectual property or (y) interfere with the ordinary conduct of the business
conducted by the Borrower and its Subsidiaries with such intellectual property; and 
 (i) precautionary financing statements filed in
connection with operating leases or other transactions that are not secured transactions. 
 “Default” means any event
that, with the passing of time or the giving of notice or both, would become an Event of Default. 
 “Defaulting Lender”
means any Lender with respect to which a Lender Default is in effect. 
 “Designated Permitted Investments” means one or
more Investments pursuant to Section 8.3(k) or (m) in which the Borrower or a Subsidiary thereof purchases or otherwise acquires any Stock of a Person, together with any other Security of such Person. 

“Designated Person” means a person or entity: 

(a) listed in the annex to, or otherwise subject to the provisions of, the Executive Order; 

(b) (i) named as a “Specially Designated National and Blocked Person” or a “Foreign Sanctions Evader” on the most
current lists published by OFAC at its official website or any replacement website or other replacement official publication of such list or (ii) listed in any sanctions-related list of designated persons maintained by the United Nations; 

(c) in which an entity or person covered by clause (a) or (b) above has 50% or greater ownership interest or that is
otherwise controlled by an entity or person covered by clause (a) or (b) above; or 
 (d) located, organized or
resident in a country or territory that is, or whose government is, the subject of Sanctions Laws and Regulations. 
 “Designated
Sales” means each of the BBI Sale, the SPDH Sale, the TechLab Sale and the Wampole Sale. 
 “Disclosure Documents”
means, collectively, (a) all confidential information memoranda and related materials prepared in connection with the syndication of the Facilities and (b) all other documents filed by any Group Member with the SEC. 

“Discount Range” has the meaning specified in Schedule 2.21. 

  
 11 

 “Disqualified Stock” means any Stock of the Borrower that, by its terms (or by
the terms of any security or other Stock into which it is convertible or for which it is exchangeable, either mandatorily or at the option of the holder thereof), or upon the happening of any event or condition stated in such terms, (a) is
mandatorily redeemable or otherwise matures and is payable (in either case, other than either solely at the option of the Borrower or solely for common Stock of the Borrower and/or Preferred Stock of the Borrower that is not Disqualified Stock
(together with cash payments in lieu of the issuance of fractional shares)), whether pursuant to a sinking fund obligation or otherwise, (b) is redeemable at the option of holder thereof (other than solely for common Stock of the Borrower
and/or Preferred Stock of the Borrower that is not Disqualified Stock (together with cash payments in lieu of the issuance of fractional shares)), in whole or in part, or is required to be repurchased by the Borrower or any of its Subsidiaries, in
whole or in part, at the option of the holder thereof or (c) is convertible into or exchangeable, either mandatorily or at the option of the holder thereof (but other than solely at the option of the Borrower), for Indebtedness or any other
Stock (other than solely common Stock of the Borrower and/or Preferred Stock of the Borrower that is not Disqualified Stock (together with cash payments in lieu of the issuance of fractional shares)), in each of the foregoing clauses (a),
(b) and (c), prior to 180 days after the Latest Maturity Date, except, in the case of clauses (a) and (b) above, if as a result of a “change of control” or “asset sale”, so long as any
rights of the holders thereof upon the occurrence of such a change of control or asset sale event are subject to (unless waived by the Required Lenders) (A) in the case of a “change of control”, (i) the prior payment in full of
the Loans and all other Obligations (other than unasserted contingent indemnification obligations), (ii) the cancellation or expiration of all Letters of Credit (or the cash collateralization of all L/C Obligations at face value plus the amount
of fees accruing thereon through expiration of the applicable Letters of Credit) and (iii) the termination of the Commitments and (B) in the case of an “asset sale”, the net cash proceeds therefrom being applied to the
Obligations as provided for in this Agreement. It is hereby acknowledged that the Borrower’s Series B Perpetual Convertible Preferred Stock, as constituted on the Closing Date, shall not be Disqualified Stock. 

“Dollars” and the sign “$” each mean the lawful money of the United States of America. 

“Domestic Person” means any “United States person” under and as defined in Section 770l(a)(30) of the Code.

 “E-Fax” means any system used to receive or transmit faxes electronically. 

“Effective Yield” means, as to any Indebtedness, the effective yield on such Indebtedness as reasonably determined by the B
Term Loan Administrative Agent, taking into account the applicable interest rate margins, interest rate benchmark floors and all fees, including recurring, up-front or similar fees or original issue discount (amortized over the shorter of
(x) the remaining life of such Indebtedness and (y) the four years following the date of incurrence thereof) payable generally to Lenders or other institutions providing such Indebtedness, but excluding (i) any arrangement,
structuring or other fees payable in connection therewith that are not generally shared with the Lenders or other institutions thereunder and (ii) any customary consent fees paid generally to consenting Lenders. 

“Electronic Transmission” means each document, instruction, authorization, file, information and any other communication
transmitted, posted or otherwise made or communicated by e-mail or E-Fax, or otherwise to or from an E-System or other equivalent service. 

  
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 “Eligible Assignee” has the meaning specified in Section 11.2(b).

 “Engagement Letter” means the Engagement Letter (including the annexes and exhibits thereto), dated June 2, 2015,
among the Arrangers, the Agents and the Borrower. 
 “Environmental Laws” means all Requirements of Law and Permits
imposing liability or standards of conduct for or relating to the regulation and protection of human health, safety, the environment and natural resources, including CERCLA, the SWDA, the Hazardous Materials Transportation Act (49 U.S.C.
§§ 5101 et seq.), the Federal Insecticide, Fungicide, and Rodenticide Act (7 U.S.C. §§ 136 et seq.), the Toxic Substances Control Act (15 U.S.C. §§ 2601 et seq.), the Clean Air Act (42 U.S.C. §§ 7401 et seq.),
the Federal Water Pollution Control Act (33 U.S.C. §§ 1251 et seq.), the Occupational Safety and Health Act (29 U.S.C. §§ 651 et seq.), the Safe Drinking Water Act (42 U.S.C. §§ 300(f) et seq.), all regulations
promulgated under any of the foregoing, all analogous Requirements of Law and Permits and any environmental transfer of ownership notification or approval statutes, including the Industrial Site Recovery Act (N.J. Stat. Ann.
§§ 13:1K-6 et seq.). 
 “Environmental Liabilities” means all Liabilities (including costs of Remedial
Actions, natural resource damages and costs and expenses of investigation and feasibility studies) that may be imposed on, incurred by or asserted against any Group Member as a result of, or related to, any claim, suit, action, investigation,
proceeding or demand by any Person, whether based in contract, tort, implied or express warranty, strict liability, criminal or civil statute or common law or otherwise, arising under any Environmental Law or in connection with any environmental,
health or safety condition or with any Release and resulting from the ownership, lease, sublease or other operation or occupation of property by any Group Member, whether on, prior or after the date hereof. 

“ERISA” means the United States Employee Retirement Income Security Act of 1974, as amended from time to time, and any
regulations promulgated thereunder. 
 “ERISA Affiliate” means, collectively, any Group Member, and any Person under common
control, or treated as a single employer, with any Group Member, within the meaning of Section 414(b), (c), (m) or (o) of the Code. 

“ERISA Event” means any of the following: (a) a reportable event described in Section 4043(b) of ERISA (or, unless
the 30-day notice requirement has been duly waived under the applicable regulations, Section 4043(c) of ERISA) with respect to a Title IV Plan; (b) the withdrawal of any ERISA Affiliate from a Title IV Plan subject to Section 4063 of
ERISA during a plan year in which it was a substantial employer, as defined in Section 4001(a)(2) of ERISA; (c) the complete or partial withdrawal of any ERISA Affiliate from any Multiemployer Plan; (d) with respect to any
Multiemployer Plan, the filing of a notice of reorganization, insolvency or termination (or treatment of a plan amendment as termination) under Section 4041A of ERISA; (e) the filing of a notice of intent to terminate a Title IV Plan (or
treatment of a plan amendment as termination) under Section 4041 of ERISA; (f) the institution of proceedings to terminate a Title IV Plan or Multiemployer Plan by the PBGC; (g) the failure to make any required contribution to any
Title IV Plan or Multiemployer Plan when due; (h) the imposition of a lien under Section 412 of the Code or Section 302 or 4068 of ERISA on any property (or rights to property, whether real or personal) of any ERISA Affiliate;
(i) the failure of a Benefit Plan or any trust thereunder intended to qualify for tax exempt status under Section 401 or 501 of the Code or other Requirements of Law to qualify thereunder; (j) a Title IV Plan is in “at risk
status” within 

  
 13 

 
the meaning of Code Section 430(i) or ERISA Section 303(i); (k) a Multiemployer Plan is in “endangered status” or “critical status” within the meaning of Code
Section 432(b) or ERISA Section 305(b); (l) an ERISA Affiliate incurs a substantial cessation of operations within the meaning of ERISA Section 4062(e), with respect to a Title IV Plan; or (m) any other event or condition
that might reasonably be expected to constitute grounds under Section 4042 of ERISA for the termination of, or the appointment of a trustee to administer, any Title IV Plan or Multiemployer Plan or for the imposition of any liability upon any
ERISA Affiliate under Title IV of ERISA other than for PBGC premiums due but not delinquent. 
 “E-Signature” means the
process of attaching to or logically associating with an Electronic Transmission an electronic symbol, encryption, digital signature or process (including the name or an abbreviation of the name of the party transmitting the Electronic Transmission)
with the intent to sign, authenticate or accept such Electronic Transmission. 
 “E-System” means any electronic system,
including Intralinks®, SyndTrak Online, ClearPar® and any other Internet or extranet-based site, whether such electronic system is
owned, operated or hosted by either Administrative Agent, any of its Related Persons or any other Person, providing for access to data protected by passcodes or other security system. 

“Eurodollar Base Rate” means the rate per annum equal to the arithmetic mean (rounded to the nearest 1/100th of 1%) of the
offered rates for deposits in Dollars with a term comparable to such Interest Period which appears on Reuters Screen LIBOR01 Page (or such other page as may replace such page on such service for the purpose of displaying the rates at which Dollar
deposits are offered by leading banks in the London interbank deposit market as designated by the Applicable Administrative Agent from time to time) at approximately 11:00 a.m., London, England time, on the second full Business Day preceding the
first day of such Interest Period; provided, however, if no comparable term for an Interest Period is available, the Eurodollar Rate shall be determined using the weighted average of the offered rates for the two terms most nearly
corresponding to such Interest Period. In the event that such rate does not appear on the Reuters Screen LIBOR01 page (or otherwise on the Reuters screen) at such time, the “Eurodollar Base Rate” shall be determined by reference to
such other comparable publicly available service for displaying the offered rate for deposit in Dollars in the London interbank market as may be selected by the Applicable Administrative Agent and, in the absence of availability, such other method
to determine such offered rate as may be selected by the Applicable Administrative Agent in its sole discretion; provided that if any such rate determined pursuant to this sentence or the preceding sentence is below zero, the Eurodollar Base
Rate shall be deemed to be zero. “Reuters Screen LIBOR01 Page” shall mean the display designated on the Reuters 3000 Xtra Page (or such other page as may replace such page on such service for the purpose of displaying the rates at which
Dollar deposits are offered by leading banks in the London interbank deposit market). 
 “Eurodollar Rate” means, with
respect to any Interest Period and for any Eurodollar Rate Loan, an interest rate per annum determined as the ratio of (a) the Eurodollar Base Rate with respect to such Interest Period for such Eurodollar Rate Loan to (b) the difference
between the number one and the Eurodollar Reserve Requirements with respect to such Interest Period and for such Eurodollar Rate Loan. Notwithstanding the foregoing, in no event shall the Eurodollar Rate with respect to any Interest Period for any
outstanding B Term Loan that is maintained as a Eurodollar Rate Loan be less than 1.00% per annum. 
 “Eurodollar Rate
Loan” means any Loan that bears interest based on the Eurodollar Rate. 

  
 14 

 “Eurodollar Reserve Requirements” means, with respect to any Interest Period and
for any Eurodollar Rate Loan, a rate per annum equal to the aggregate, without duplication, of the maximum rates (expressed as a decimal number) of reserve requirements in effect 2 Business Days prior to the first day of such Interest Period
(including basic, supplemental, marginal and emergency reserves) under any regulations of the Federal Reserve Board or other Governmental Authority having jurisdiction with respect thereto dealing with reserve requirements prescribed for
eurocurrency funding (currently referred to as “eurocurrency liabilities” in Regulation D of the Federal Reserve Board) maintained by a member bank of the United States Federal Reserve System. 

“Event of Default” has the meaning specified in Section 9.1. 

“Excess Cash Flow” means, for any period, (a) Consolidated EBITDA of the Borrower for such period, minus
(b) without duplication, (i) the aggregate amount of all prepayments or other non-scheduled payments of principal of Indebtedness of the Borrower or any of its Subsidiaries made in cash during such period (other than in respect of any
revolving credit facility to the extent there is not an equivalent permanent reduction in commitments thereunder), excluding (x) the Loans, (y) prepayments and other non-scheduled payments made using the Available Amount, and
(z) prepayments and other non-scheduled payments funded with the proceeds of long-term Indebtedness (other than with Loans under the Revolving Credit Facility) or the proceeds of asset sales outside of the ordinary course of business or
directly with proceeds received from the issuance of common Stock or Preferred Stock of the Borrower, (ii) the aggregate amount of all scheduled amortization (or similar) payments made in cash on Indebtedness (including the Term Loans) during
such period, (iii) any Capital Expenditure made in cash by the Borrower or any of its Subsidiaries during such period to the extent permitted by this Agreement, excluding the portion thereof financed with long-term Indebtedness (other than with
Loans under the Revolving Credit Facility) or directly with proceeds received from the issuance of common Stock or Preferred Stock of the Borrower, (iv) the Consolidated Cash Interest Expense of the Borrower and its Subsidiaries for such
period, (v) any cash losses from extraordinary or non-recurring items, (vi) any cash paid during such period or payable with respect to such period to satisfy obligations for income taxes or other taxes measured by net income,
(vii) cash restructuring costs associated with any Permitted Acquisition for such period, (viii) any Permitted Acquisition Consideration paid in cash and any Investments pursuant to Section 8.3(j) or
(k) made in cash, in each case, by the Borrower or any of its Subsidiaries during such period to the extent permitted by this Agreement, but excluding the portion thereof financed with long-term Indebtedness (other than with Loans under
the Revolving Credit Facility) or directly with proceeds received from the issuance of common Stock or Preferred Stock of the Borrower, (ix) any increase in the Working Capital of the Borrower and its Subsidiaries during such period (measured
as the excess of such Working Capital at the end of such period over such Working Capital at the beginning of such period), (x) the aggregate consideration paid in cash by the Group Members for all Permitted Stock Repurchases and all
redemptions, purchases or other acquisition or net investments by the Borrower of its Common Stock pursuant to Section 8.5(c) during such period, but excluding the portion thereof financed with long-term Indebtedness (other than with
Loans under the Revolving Credit Facility) or directly with proceeds received from the issuance of common Stock or Preferred Stock of the Borrower, (xi) the aggregate amount of all cash dividends on Stock of the Borrower pursuant to
Section 8.5(f) during such period, but excluding the portion thereof financed with long-term Indebtedness (other than with Loans under the Revolving Credit Facility) or directly with proceeds received from the issuance of common Stock or
Preferred Stock of the Borrower, and (xii) the aggregate amount of all fees, costs and 

  
 15 

 
expenses paid in cash during such period in connection with the incurrence or repayment of Indebtedness (including cash advisor, professional and investment banking fees, arranger fees,
underwriting fees, prepayment premiums and/or fees, tender offer premiums and/or fees, and consent and/or amendment fees), in each case, to the extent that such fees, costs and expenses are not (x) expensed during such period or deducted in
calculating Consolidated EBITDA for such period or (y) paid directly with the proceeds of Indebtedness incurred in connection therewith (excluding any incurrence of Indebtedness under a revolving credit facility), and plus
(c) without duplication, (i) any decrease in the Working Capital of the Borrower and its Subsidiaries during such period (measured as the excess of such Working Capital at the beginning of such period over such Working Capital at the end
thereof), and (ii) any cash gains or income from extraordinary or non-recurring items for such period (only to the extent of any increase in Consolidated Net Income resulting therefrom, but, for the avoidance of doubt, excluding any cash gains
or income (x) deducted from Consolidated EBITDA pursuant to clause (c)(iii) of the definition thereof or (y) resulting from any Sale of property or Property Loss Event which is subject to the mandatory prepayment provisions of
Section 2.8(c) (including any Net Cash Proceeds that are used (or to be used) to make one or more Permitted Reinvestments in accordance with Section 2.8(c)). 

“Excluded Foreign Subsidiary” means (i) any Subsidiary of the Borrower that is not a Domestic Person and (ii) any
Subsidiary of the Borrower that is a Domestic Person that is a direct or indirect Subsidiary of a Foreign Subsidiary that is a “controlled foreign corporation” within the meaning of Section 957 of the Code; provided,
however, that (x) the Collateral Agent and the Borrower may agree that, despite the foregoing, any such Subsidiary shall not be an “Excluded Foreign Subsidiary”, (y) no such Subsidiary shall be an “Excluded
Foreign Subsidiary” if (A) such Subsidiary has entered into any Guaranty Obligations with respect to, (B) such Subsidiary has granted a security interest in any of its property to secure, or (C) more than 65% of the Voting
Stock of such Subsidiary was pledged to secure, in each such case, directly or indirectly, any Indebtedness (other than the Obligations) of any Loan Party (it being understood that in no event shall any joint and several liability of such Subsidiary
and any Loan Party for any Permitted Acquisition Debt under clause (i) of the definition thereof be deemed such a Guaranty Obligation under preceding clause (A) so long as such Subsidiary does not guaranty any other Indebtedness of any
Loan Party) and (z) in no event shall Alere US Holdings, LLC or Alere International Holdings Corp. be an Excluded Foreign Subsidiary. 

“Excluded Information” has the meaning specified in Section 2.21(d). 

“Excluded Investment” has the meaning specified in Section 8.3. 

“Excluded Sales” has the meaning specified in Section 2.8(c). 

“Excluded Swap Obligation” means, with respect to any Guarantor, any Swap Obligation if, and to the extent that, all or a
portion of the Guaranty Obligation of such Guarantor of, or the grant by such Guarantor of a security interest to secure, such Swap Obligation (or any Guaranty Obligation thereof) is or becomes illegal under the Commodity Exchange Act or any rule,
regulation or order of the Commodity Futures Trading Commission (or the application or official interpretation of any thereof) by virtue of such Guarantor’s failure for any reason to constitute an “eligible contract participant” as
defined in the Commodity Exchange Act and the regulations thereunder at the time the Guaranty Obligation of such Guarantor or the grant of such security interest becomes effective with respect to such Swap Obligation. If a Swap Obligation arises
under a master agreement governing more than one swap, such exclusion shall apply only to the portion of such Swap Obligation that is attributable to swaps for which such Guaranty Obligation or security interest is or becomes illegal. 

  
 16 

 “Excluded Taxes” has the meaning specified in Section 2.17(e). 

“Executive Order” means the Executive Order No. 13224 of September 23, 2001, entitled Blocking Property and
Prohibiting Transactions With Persons Who Commit, Threaten to Commit, or Support Terrorism. 
 “Existing 2016 Subordinated
Convertible Notes” means the 3% unsecured subordinated convertible notes due May 15, 2016, issued by the Borrower pursuant to the Existing 2016 Subordinated Convertible Notes Indenture, in an aggregate principal amount of $150,000,000
(as such amount may be reduced by any repayments, prepayments, redemptions, repurchases, sinking fund or similar payments of principal thereof). 

“Existing 2016 Subordinated Convertible Notes Indenture” means the Indenture in respect of the Existing 2016 Subordinated
Convertible Notes, dated as of May 14, 2007, among the Borrower, as issuer, and U.S. Bank Trust National Association, as indenture trustee, as in effect on the Closing Date and as the same may be amended, modified or supplemented from time to
time in accordance with the terms hereof and thereof. 
 “Existing 2018 Senior Notes” means the 7.250% senior unsecured
notes due July 1, 2018, issued by the Borrower pursuant to the Existing 2018 Senior Notes Indenture, in an aggregate principal amount of $450,000,000 (as such amount may be reduced by any repayments, prepayments, redemptions, repurchases,
sinking fund or similar payments of principal thereof). 
 “Existing 2018 Senior Notes Indenture” means the Indenture in
respect of the Existing 2018 Senior Notes, dated as of August 11, 2009, between the Borrower, as issuer, and The Bank of New York Mellon Trust Company, N.A., as trustee, as supplemented by that certain Fifteenth Supplemental Indenture thereto,
dated as of December 11, 2012, among the Borrower, as issuer, certain of its Subsidiaries as guarantors, and The Bank of New York Mellon Trust Company, N.A., as trustee, and as further amended, supplemented and in effect on the Closing Date and
as the same may be amended, modified or supplemented from time to time in accordance with the terms hereof and thereof. 
 “Existing
2018 Subordinated Notes” means the 8.625% unsecured subordinated notes due October 1, 2018, issued by the Borrower pursuant to the Existing 2018 Subordinated Notes Indenture, in an aggregate principal amount of $400,000,000 (as such
amount may be reduced by any repayments, prepayments, redemptions, repurchases, sinking fund or similar payments of principal thereof). 

“Existing 2018 Subordinated Notes Indenture” means the Indenture in respect of the Existing 2018 Subordinated Notes, dated as
of May 12, 2009, between the Borrower, as issuer, and U.S. Bank National Association, as trustee, as supplemented by that certain Ninth Supplemental Indenture thereto, dated as of September 21, 2010, among the Borrower, as issuer, certain
of its Subsidiaries as guarantors, and U.S. Bank National Association, as trustee, and as further amended, supplemented and as in effect on the Closing Date and as the same may be amended, modified or supplemented from time to time in accordance
with the terms hereof and thereof. 

  
 17 

 “Existing 2020 Subordinated Notes” means the 6.500% unsecured subordinated notes
due June 15, 2020, issued by the Borrower pursuant to the Existing 2020 Subordinated Notes Indenture, in an aggregate principal amount of $425,000,000 (as such amount may be reduced by any repayments, prepayments, redemptions, repurchases,
sinking fund or similar payments of principal thereof). 
 “Existing 2020 Subordinated Notes Indenture” means the Indenture
in respect of the Existing 2020 Subordinated Notes, dated as of May 12, 2009, between the Borrower, as issuer, and U.S. Bank National Association, as trustee, as supplemented by that certain Sixteenth Supplemental Indenture thereto, dated as of
May 24, 2013, among the Borrower, as issuer, certain of its Subsidiaries as guarantors, and U.S. Bank National Association, as trustee, and as further amended, supplemented and as in effect on the Closing Date and as the same may be amended,
modified or supplemented from time to time in accordance with the terms hereof and thereof. 
 “Existing Credit Agreement”
means that certain Credit Agreement, dated as of June 30, 2011, among the Borrower, as borrower, the lenders party thereto, Jefferies Finance LLC, as syndication agent, Credit Suisse Securities (USA) LLC, Goldman Sachs Bank USA, DnB Nor Bank
ASA and SunTrust Bank, as co-documentation agents, Jefferies Finance LLC, GE Capital Markets, Inc., Credit Suisse Securities (USA) LLC and Goldman Sachs Bank USA, as joint lead arrangers and bookrunners, and General Electric Capital Corporation, as
administrative agent, as in effect on the Closing Date. 
 “Existing Indebtedness” has the meaning specified in
Section 8.1(b). 
 “Existing Letter of Credit” has the meaning specified in Section 2.4(a). 

“Existing Notes” means, collectively, the Existing 2018 Senior Notes and the Existing Subordinated Notes. 

“Existing Notes Documents” means, collectively, the Existing Notes, the Existing Notes Indentures and any other document
related to any of the foregoing. 
 “Existing Notes Indentures” means, collectively, the Existing 2018 Senior Notes
Indenture and the Existing Subordinated Notes Indentures. 
 “Existing Subordinated Notes” means, collectively, the
Existing 2020 Subordinated Notes, the Existing 2018 Subordinated Notes and the Existing 2016 Subordinated Convertible Notes. 

“Existing Subordinated Notes Indentures” means, collectively, the Existing 2016 Subordinated Convertible Notes Indenture, the
Existing 2018 Subordinated Notes Indenture and the Existing 2020 Subordinated Notes Indenture. 
 “Extended Revolving Credit
Commitments” has the meaning specified in Section 2.23(a). 
 “Extended Revolving Credit Facility”
means the Extended Revolving Credit Commitments and the provisions herein related to the Extended Revolving Loans and any Swing Loans or Letters of Credit incurred under the Extended Revolving Credit Commitments. 

“Extended Revolving Loans” has the meaning specified in Section 2.23(a). 

  
 18 

 “Extended Term Loan Facility” means the Extended Term Loans and the provisions
herein related to the Extended Term Loans. 
 “Extended Term Loan Commitment” has the meaning specified in the definition
of “Term Loan Commitment”. 
 “Extended Term Loans” has the meaning specified in Section 2.23(a).

 “Extending Lenders” has the meaning specified in Section 2.23(a). 

“Extending Revolving Credit Lender” has the meaning specified in Section 2.23(a). 

“Extending Term Lender” has the meaning specified in Section 2.23(a). 

“Extension” has the meaning specified in Section 2.23(a). 

“Extension Amendment” has the meaning specified in Section 2.23(d). 

“Extension Election” has the meaning specified in Section 2.23(c). 

“Extension Request” has the meaning specified in Section 2.23(a). 

“Expiration Time” has the meaning specified in Schedule 2.21. 

“Facilities” means (a) each Initial Term Loan Facility, (b) each Incremental Term Loan Facility, (c) each
Extended Term Loan Facility, (d) each Specified Refinancing Term Loan Facility, (e) the Revolving Credit Facility, (f) each Extended Revolving Credit Facility and (g) each Specified Refinancing Revolving Credit Facility. 

“FATCA” means Sections 1471 through 1474 of the Code, as enacted on the Closing Date (and any amended or successor provisions
thereto that are substantively comparable and not materially more onerous to comply with), the regulations promulgated thereunder or published administrative guidance implementing such Sections of the Code, and any “intergovernmental
agreements” within the meaning of regulations promulgated under Section 1471 of the Code. 
 “Federal Funds Rate”
means, for any period, a fluctuating interest rate per annum equal for each day during such period to the weighted average (rounded upwards, if necessary, to the next 1/100th of 1.0%) of the rates on overnight federal funds transactions with members
of the United States Federal Reserve System arranged by federal funds brokers, as determined by the Applicable Administrative Agent in its sole discretion. 

“Federal Reserve Board” means the Board of Governors of the United States Federal Reserve System and any successor thereto.

 “Fee Letters” means, collectively, (i) the letter agreement, dated June 2, 2015, addressed to the Borrower
from the Pro Rata Administrative Agent and accepted by the Borrower, with respect to certain fees to be paid from time to time to the Pro Rata Administrative Agent and (ii) the letter agreement, dated June 2, 2015, addressed to the
Borrower from the B Term Loan Administrative Agent and accepted by the Borrower, with respect to certain fees to be paid from time to time to the B Term Loan Administrative Agent. 

  
 19 

 “financial maintenance covenants” means any “financial maintenance
covenant” tested on a periodic basis (whether stated as a covenant, event of default or other provision with similar effect, provided that “incurrence-based” financial tests shall not be treated as a “financial maintenance
covenant” for this purpose). 
 “Financial Statement” means (i) the Borrower’s financial statements referred
to in clause (ii) of Section 4.4(a) and (ii) each financial statement delivered pursuant to Section 6.1(a) or (b). 

“Fiscal Quarter” means each 3 fiscal month period ending on March 31, June 30, September 30 or
December 31. 
 “Fiscal Year” means the twelve-month period ending on December 31. 

“Foreign Subsidiary” means any Subsidiary of the Borrower which is organized and existing under the laws of any jurisdiction
outside of the United States of America (which jurisdictions outside the United States of America shall include Puerto Rico or any other territory of the United States of America). 

“Fronting Exposure” means, at any time there is a Revolving Credit Lender that is a Defaulting Lender, (a) with respect
to any L/C Issuer, such Defaulting Lender’s L/C Exposure with respect to Letters of Credit issued by such L/C Issuer other than L/C Obligations as to which such Defaulting Lender’s participation obligation has been reallocated to other
Revolving Credit Lenders or cash collateralized in a manner reasonably satisfactory to the applicable L/C Issuer in aggregate amount equal to 105% of such Defaulting Lender’s L/C Exposure, and (b) with respect to the Swingline Lender, such
Defaulting Lender’s Swingline Exposure other than Swing Loans as to which such Defaulting Lender’s participation obligation has been reallocated to other Revolving Credit Lenders. 

“GAAP” means generally accepted accounting principles in the United States of America, as in effect from time to time, set
forth in the opinions and pronouncements of the Accounting Principles Board and the American Institute of Certified Public Accountants, in the statements and pronouncements of the Financial Accounting Standards Board and in such other statements by
such other entity as may be in general use by significant segments of the accounting profession that are applicable to the circumstances as of the date of determination. Subject to Section 1.3, all references to “GAAP”
shall be to GAAP applied consistently with the principles used in the preparation of the Financial Statements described in Section 4.4(a). 

“GE Capital” has the meaning provided in the preamble hereto. 

“Goldman” has the meaning provided in the preamble hereto. 

“Governmental Authority” means any nation, sovereign, government, state or other political subdivision, any agency, authority
or instrumentality thereof and any entity or authority exercising executive, legislative, taxing, judicial, regulatory or administrative functions of or pertaining to government, including any central bank, stock exchange, regulatory body,
arbitrator, public sector entity, supra-national entity (including the European Union and the European Central Bank) and any self-regulatory organization (including the National Association of Insurance Commissioners). 

“Group Members” means, collectively, the Borrower and each of its Subsidiaries. 

  
 20 

 “Group Members’ Accountants” means PricewaterhouseCoopers LLP or other
nationally-recognized independent registered certified public accountants. 
 “Guarantor” means each Subsidiary of the
Borrower listed on Schedule 4.3(a) that has executed and delivered the Guaranty and Security Agreement and that is not an Excluded Foreign Subsidiary, and each other Person that enters into any Guaranty Obligation with respect to any
Obligation of any Loan Party pursuant to the Guaranty and Security Agreement. 
 “Guaranty and Security Agreement” means a
guaranty and security agreement, in substantially the form of Exhibit H, among the Collateral Agent, the Borrower and the Guarantors from time to time party thereto. 

“Guaranty Obligation” means, as applied to any Person, any direct or indirect liability, contingent or otherwise, of such
Person for any Indebtedness, lease, dividend or other obligation (the “primary obligation”) of another Person (the “primary obligor”), if the purpose or intent of such Person in incurring such liability, or the
economic effect thereof, is to guarantee such primary obligation or provide support or assurance to the holder of such primary obligation or to protect or indemnify such holder against loss with respect to such primary obligation, including
(a) the direct or indirect guaranty, endorsement (other than for collection or deposit in the ordinary course of business), co-making, discounting with recourse or sale with recourse by such Person of any primary obligation, (b) the
incurrence of reimbursement obligations with respect to any letter of credit or bank guarantee in support of any primary obligation, (c) the existence of any Lien, or any right, contingent or otherwise, to receive a Lien, on the property of
such Person securing any part of any primary obligation (but only to the extent of the value of such property securing such obligation) and (d) any liability of such Person for a primary obligation through any Contractual Obligation (contingent
or otherwise) or other arrangement (i) to purchase, repurchase or otherwise acquire such primary obligation or any security therefor or to provide funds for the payment or discharge of such primary obligation (whether in the form of a loan,
advance, stock purchase, capital contribution or otherwise), (ii) to maintain the solvency, working capital, equity capital or any balance sheet item, level of income or cash flow, liquidity or financial condition of any primary obligor,
(iii) to make take-or-pay or similar payments in respect of the primary obligation, (iv) to purchase, sell or lease (as lessor or lessee) any property, or to purchase or sell services, primarily for the purpose of enabling the primary
obligor to satisfy such primary obligation or to protect the holder of such primary obligation against loss or (v) to supply funds to or in any other manner invest in, such primary obligor (including to pay for property or services irrespective
of whether such property is received or such services are rendered) for the purpose of enabling the primary obligor to satisfy such primary obligation; provided, however, that “Guaranty Obligations” shall not include
(x) endorsements for collection or deposit in the ordinary course of business and (y) product warranties given in the ordinary course of business. The outstanding amount of any Guaranty Obligation shall equal the outstanding amount of the
primary obligation so guaranteed or otherwise supported or, if lower, the stated maximum reasonably anticipated amount for which such Person may be liable under such Guaranty Obligation. 

“Hazardous Material” means any substance, material or waste that is classified, regulated or otherwise characterized under
any Environmental Law as hazardous, toxic, a contaminant or a pollutant or by other words of similar meaning or regulatory effect, including petroleum or any fraction thereof, asbestos, polychlorinated biphenyls and radioactive substances. 

  
 21 

 “Healthcare Laws” means (a) Federal Food, Drug and Cosmetic Act as
interpreted and enforced by the U.S. Food and Drug Administration, Department of Health and Human Services, and United States Department of Justice; (b) the Clinical Laboratory Improvement Amendments (42 U.S.C. § 263a) and the
regulations promulgated pursuant thereto; (c) all federal and state fraud and abuse laws, including, but not limited to the federal Anti-Kickback Statute (42 U.S.C. §1320a-7(b)), the federal Ethics in Patient Referrals Act (42 U.S.C.
§§1395mm et. seq.), the Stark Law (42 U.S.C. §1395nn and §1395(q)), the civil False Claims Act (31 U.S.C. §3729 et. seq.), TRICARE (10 U.S.C. Section 1071 et. seq.), Sections 1320a-7 and 1320a-7a of Title 42 of the
United States Code and the regulations promulgated pursuant to such statutes; (d) the Health Insurance Portability and Accountability Act of 1996 (Pub. L. No. 104-191) and the regulations promulgated thereunder; (e) Medicare (Title
XVIII of the Social Security Act) and the regulations promulgated thereunder; (f) Medicaid (Title XIX of the Social Security Act) and the regulations promulgated thereunder; (g) quality, safety and accreditation standards and requirements
of all applicable state laws or Governmental Authorities; (h) licensure laws and regulations; and (i) any and all other applicable medical, medical devices or health care laws, regulations, manual provisions, policies and administrative
guidance, each of clauses (a) through (h) above as may be amended from time to time. 
 “Hedging
Agreement” means any Interest Rate Contract, foreign exchange, swap, option or forward contract, spot, cap, floor or collar transaction, any other derivative instrument and any other similar transaction and any other similar agreement or
arrangement designed to alter the risks of any Person arising from fluctuations in any underlying variable. 
 “Immaterial
Subsidiary” means any Subsidiary of the Borrower (other than Alere US Holdings, LLC) which (a) generated less than 5% of the consolidated revenues of the Borrower and its Subsidiaries for the fiscal period most recently ended and
(b) owned less than 5% of the assets (as determined on a book value basis) of the Borrower and its Subsidiaries on a consolidated basis for such fiscal period; provided that no Group Member which otherwise satisfies the criteria set
forth in clauses (a) and (b) above shall be treated as an Immaterial Subsidiary in this Agreement if (x) the aggregate revenues generated by all Immaterial Subsidiaries would exceed 10% of the consolidated revenues of
the Borrower and its Subsidiaries for the fiscal period most recently ended or (y) all Immaterial Subsidiaries own more than 10% of the assets of the Borrower and its Subsidiaries on a consolidated basis, in each case after including such Group
Member as an Immaterial Subsidiary for purposes of calculating compliance with clauses (x) and (y) above. 

“Inactive Subsidiaries” means, collectively, those Subsidiaries of the Borrower set forth on Schedule 1.1(a). 

“Increasing Lenders” has the meaning specified in Section 2.19(a). 

“Incremental Amendment” has the meaning specified in Section 2.19(c). 

“Incremental Revolving Credit Commitments” has the meaning specified in Section 2.19(a). 

“Incremental Term Loan” has the meaning specified in Section 2.19(a). 

“Incremental Term Loan Commitments” has the meaning specified in Section 2.19(a). 

  
 22 

 “Incremental Term Loan Facility” means the Incremental Term Loan Commitments and
the provisions herein related to the Incremental Term Loans. 
 “Incremental Term Loan Maturity Date” means, for any
Tranche of Incremental Term Loans, the final maturity date set forth for such Tranche of Incremental Term Loans, provided that the final maturity date for all Incremental Term Loans of a given Tranche shall be the same date. 

“Indebtedness” of any Person means, without duplication, any of the following, whether or not matured: (a) all
indebtedness for borrowed money, (b) all obligations evidenced by notes, bonds, debentures or similar instruments, (c) all reimbursement and other obligations with respect to (i) letters of credit, bank guarantees or bankers’
acceptances or (ii) surety, customs, reclamation or performance bonds (in each case not related to judgments or litigation) other than those entered into in the ordinary course of business, (d) all obligations to pay the deferred purchase
price of property or services (other than trade payables incurred in the ordinary course of business that are unsecured and customary adjustments of purchase price, contingent payments, earnout payments or similar obligations of any Group Member
arising under any of the documents pertaining to a merger or acquisition or a Sale), (e) all obligations created or arising under any conditional sale or other title retention agreement, regardless of whether the rights and remedies of the
seller or lender under such agreement in the event of default are limited to repossession or sale of such property, (f) all Capitalized Lease Obligations, (g) all obligations, whether or not contingent, to purchase, redeem, repurchase,
retire, defease or otherwise acquire for value (other than solely at the option of such Person) any Disqualified Stock of such Person, in each case for cash (other than cash in lieu of fractional shares) or in exchange for (or by other delivery of)
Indebtedness or any other Disqualified Stock, prior to the date that is 180 days after the Latest Maturity Date in effect at the time of the incurrence or issuance of such Indebtedness, valued at the maximum fixed redemption or purchase or
repurchase price of such Disqualified Stock thereunder, except, in the case of this clause (g), for any such obligations solely as a result of a “change of control” or “asset sale”, so long as any rights of the holders
thereof upon the occurrence of such a change of control or asset sale event are subject to (unless waived by the Required Lenders) (A) in the case of a “change of control”, (i) the prior payment in full of the Loans and all other
Obligations (other than unasserted contingent indemnification obligations), (ii) the cancellation or expiration of all Letters of Credit (or the cash collateralization of all L/C Obligations at face value plus the amount of fees accruing
thereon through expiration of the applicable Letters of Credit) and (iii) the termination of the Commitments and (B) in the case of an “asset sale”, the net cash proceeds therefrom being applied to the Obligations as provided for
in this Agreement, (h) the net amount of all payments that would be required to be made in respect of any Hedging Agreement in the event of a termination (including an early termination) on the date of determination, and (i) all Guaranty
Obligations for obligations of any other Person constituting Indebtedness of such other Person; provided, however, that the items in each of clauses (a) through (h) above shall constitute
“Indebtedness” of such Person solely to the extent, directly or indirectly, (x) such Person is liable for any part of any such item, (y) any such item is secured by a Lien on such Person’s property or (z) any other
Person has a right, contingent or otherwise, to cause such Person to become liable for any part of any such item or to grant such a Lien. Any amount of any Indebtedness for which recourse is expressly limited to a specific asset shall be limited to
the fair market value of such asset. 
 “Indemnified Matters” has the meaning specified in Section 11.4. 

“Indemnitee” has the meaning specified in Section 11.4. 

  
 23 

 “Individual Exposure” of any Lender means, at any time, the sum of (a) the
aggregate principal amount of all Revolving Loans made by such Lender and then outstanding, (b) such Lender’s Revolving Credit Percentage in the aggregate principal amount of all Swing Loans then outstanding and (c) such Lender’s
Revolving Credit Percentage in the aggregate amount of all L/C Obligations at such time. 
 “Initial Projections” means
those financial projections covering the Fiscal Years ending in 2015 through 2019 and delivered to the Administrative Agents by the Borrower prior to the date hereof. 

“Initial Term Loan” means, collectively, each A Term Loan and each B Term Loan. 

“Initial Term Loan Commitment” means, collectively, the A Term Loan Commitment and the B Term Loan Commitment. 

“Initial Term Loan Facility” means the Initial Term Loan Commitments and the provisions herein related to the Initial Term
Loans. 
 “Intellectual Property” means all rights, title and interests in or relating to intellectual property and
industrial property arising under any Requirement of Law and all IP Ancillary Rights relating thereto, including all Copyrights, Patents, Trademarks, Internet Domain Names, Trade Secrets and IP Licenses. 

“Interest Period” means, with respect to any Eurodollar Rate Loan, the period commencing on the date such Eurodollar Rate
Loan is made or converted to a Eurodollar Rate Loan or, if such loan is continued, on the last day of the immediately preceding Interest Period therefor and, in each case, ending 1, 2, 3 or 6 months (or if agreed to by all Lenders of the respective
Tranche of Loans, 12 months) thereafter, as selected by the Borrower; provided, however, that (a) if any Interest Period would otherwise end on a day that is not a Business Day, such Interest Period shall be extended to the next
succeeding Business Day, unless the result of such extension would be to extend such Interest Period into another such Business Day falls in the next calendar month, in which case such Interest Period shall end on the immediately preceding Business
Day, (b) any Interest Period that begins on the last Business Day of a calendar month (or on a day for which there is no numerically corresponding day in the calendar month at the end of such Interest Period) shall end on the last Business Day
of a calendar month, (c) the Borrower may not select any Interest Period in respect of any Tranche of Loans ending after the Maturity Date for such Tranche of Loans, (d) the Borrower may not select any Interest Period in respect of Loans
having an aggregate principal amount of less than $1,000,000 and (e) there shall be outstanding at any one time no more than 10 Interest Periods in respect of any Tranche of Loans (or such greater number for any Tranche of Loans as may be
permitted by the Applicable Administrative Agent). 
 “Interest Rate Contracts” means all interest rate swap agreements,
interest rate cap agreements, interest rate collar agreements and interest rate insurance. 
 “Internet Domain Names” means
all right, title and interest (and all related IP Ancillary Rights) relating to Internet domain names. 
 “Investment”
means, with respect to any Person, directly or indirectly, (a) to own, purchase or otherwise acquire, in each case whether beneficially or otherwise, any investment in, 

  
 24 

 
including any interest in, any Security of any other Person (other than any evidence of any Obligation), (b) to purchase or otherwise acquire, whether in one transaction or in a series of
transactions, all or substantially all of the property of any other Person or a business conducted by any other Person or all or substantially all of the assets constituting the business of a division, branch, brand or other unit operation of any
other Person, (c) to incur, or to remain liable under, any Guaranty Obligation for Indebtedness of any other Person, to assume the Indebtedness of any other Person or to make, hold, purchase or otherwise acquire, in each case directly or
indirectly, any loan, advance, commitment to lend or advance, or other extension of credit (including by deferring or extending the date of, in each case outside the ordinary course of business, the payment of the purchase price for Sales of
property or services to any other Person, to the extent such payment obligation constitutes Indebtedness of such other Person), excluding deposits with financial institutions available for withdrawal on demand, prepaid expenses, accounts receivable
and similar items created in the ordinary course of business or (d) to make, directly or indirectly, any contribution to the capital of any other Person. 

“IP Ancillary Rights” means, with respect to any Intellectual Property, as applicable, all foreign counterparts to, and all
divisionals, reversions, continuations, continuations-in-part, reissues, reexaminations, renewals and extensions of, such Intellectual Property and all income, royalties, proceeds and Liabilities at any time due or payable or asserted under or with
respect to any of the foregoing or otherwise with respect to such Intellectual Property, including all rights to sue or recover at law or in equity for any past, present or future infringement, misappropriation, dilution, violation or other
impairment thereof, and, in each case, all rights to obtain any other IP Ancillary Right. 
 “IP License” means all
Contractual Obligations (and all related IP Ancillary Rights), whether written or oral, granting any right, title and interest in or relating to any Intellectual Property. 

“IRS” means the Internal Revenue Service of the United States and any successor thereto. 

“Issue” means, with respect to any Letter of Credit, to issue, extend the expiration date of, renew (including by failure to
object to any automatic renewal on the last day such objection is permitted), increase the face amount of, or reduce or eliminate any scheduled decrease in the face amount of, such Letter of Credit, or to cause any Person to do any of the foregoing.
The terms “Issued” and “Issuance” have correlative meanings. 
 “Junior Indebtedness”
means any Indebtedness in respect of the Existing Notes (and any Permitted Refinancing of the Existing Notes (including the New 2023 Subordinated Notes)), any Subordinated Debt, any Permitted Acquisition Debt under clause (a)(i) of the
definition thereof (and any Permitted Refinancing thereof) incurred in reliance on Section 8.1(i) and any Permitted Additional Debt (including any Permitted Refinancing thereof) incurred in reliance on Section 8.1(n) to the
extent that such Permitted Additional Debt is unsecured, Subordinated Debt or secured by a Lien ranking junior to the Lien securing the Obligations. 

“L/C Back-Stop Arrangements” has the meaning specified in Section 2.20(a)(ii). 

“L/C Cash Collateral Account” means any Cash Collateral Account (a) specifically designated as such by the Borrower in a
notice to the Pro Rata Administrative Agent and (b) from and after the effectiveness of such notice, not containing any funds other than those required under the Loan Documents to be placed therein. 

  
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 “L/C Exposure” means, at any time, the aggregate amount of all L/C Obligations
at such time in respect of Letters of Credit. The L/C Exposure of any Revolving Credit Lender at any time shall be its Revolving Credit Percentage of the aggregate L/C Exposure at such time. 

“L/C Issuer” means (a) GE Capital or any of its designated Affiliates and (b) each Person that hereafter becomes an
L/C Issuer with the approval of, and pursuant to an agreement with and in form and substance satisfactory to, the Pro Rata Administrative Agent, the Borrower and such Person to become an L/C Issuer, in each case in their capacity as L/C Issuers
hereunder and together with their successors. 
 “L/C Obligations” means, for any Letter of Credit at any time, the sum of
(a) the L/C Reimbursement Obligations at such time for such Letter of Credit and (b) the aggregate maximum undrawn face amount of such Letter of Credit outstanding at such time. 

“L/C Reimbursement Agreement” has the meaning specified in Section 2.4(a). 

“L/C Reimbursement Date” has the meaning specified in Section 2.4(e). 

“L/C Reimbursement Obligation” means, for any Letter of Credit, the obligation of the Borrower to the L/C Issuer thereof, as
and when matured, to pay all amounts drawn under such Letter of Credit. 
 “L/C Request” has the meaning specified in
Section 2.4(b). 
 “L/C Sublimit” means $50,000,000. 

“Latest Maturity Date” means, at any date of determination, the latest Maturity Date applicable to any Tranche of Loans at
such time under this Agreement (for this purpose only however, determined without regard to the Scheduled A Term Loan Springing Maturity Date, the Scheduled B Term Loan Springing Maturity Date or the Scheduled Revolving Credit Springing Maturity
Date). 
 “Lender Default” means, subject to Section 2.20(d), as to any Lender (a) failure to
(i) fund all or any portion of any Borrowing, or, in the case of a Revolving Credit Lender, to fund its portion of any unreimbursed payment with respect to a Letter of Credit pursuant to Section 2.4(f), in each case, within two
Business Days of the date such Borrowing or unreimbursed payment were required to be funded hereunder unless such Lender notifies the Applicable Administrative Agent and the Borrower in writing that such failure is the result of such Lender’s
determination that one or more conditions precedent to funding (each of which conditions precedent, together with any applicable default, shall be specifically identified in such notice) has not been satisfied, or (ii) pay to the
Applicable Administrative Agent, any L/C Issuer, the Swingline Lender or any other Lender any other amount required to be paid by it hereunder (including in respect of its participation in Letters of Credit or Swing Loans) within two Business
Days of the date when due, (b) if such Lender has notified the Borrower, the Applicable Administrative Agent, any L/C Issuer or the Swingline Lender in writing that it does not intend to comply with its funding obligations hereunder, or has
made a public statement to that effect (unless such writing or public statement relates to such Lender’s obligation to fund all or any portion of any Borrowing, or, in the case of a Revolving Credit Lender, to fund its
portion of any unreimbursed payment with respect to a Letter of Credit pursuant to Section 2.4(f), in each case, and states that such position is based on such Lender’s determination that a condition precedent to
funding (which condition 

  
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precedent, together with any applicable default, shall be specifically identified in such writing or public statement) cannot be satisfied), (c) failure, within three Business Days after
written request by the Applicable Administrative Agent or the Borrower, to confirm in writing to the Applicable Administrative Agent and the Borrower that it will comply with its prospective funding obligations hereunder (provided that such
Lender Default shall cease pursuant to this clause (c) upon receipt of such written confirmation by the Applicable Administrative Agent and the Borrower), or (d) such Lender has, or has a direct or indirect parent company that has,
(i) become the subject of a proceeding under any Requirement of Law relating to bankruptcy, insolvency or reorganization or relief of debtors, or (ii) had appointed for it a receiver, custodian, conservator, trustee, administrator,
assignee for the benefit of creditors or similar Person charged with reorganization or liquidation of its business or assets, including the Federal Deposit Insurance Corporation or any other state or federal regulatory authority acting in such a
capacity; provided that a Lender Default shall not exist solely by virtue of the ownership or acquisition of any equity interest in that Lender or any direct or indirect parent company thereof by a Governmental Authority so long as such
ownership interest does not result in or provide such Lender with immunity from the jurisdiction of courts within the United States or from the enforcement of judgments or writs of attachment on its assets or permit such Lender (or such Governmental
Authority) to reject, repudiate, disavow or disaffirm any contracts or agreements made with such Lender. Any determination by the Applicable Administrative Agent that a Lender Default has occurred under any one or more of clauses
(a) through (d) above shall be conclusive and binding absent manifest error, and such Lender shall be deemed to be a Defaulting Lender (subject to Section 2.20(d)) upon delivery of written notice of such
determination to the Borrower, each L/C Issuer, the Swingline Lender, each Lender and the other Administrative Agent. 

“Lenders” means, collectively, the Swingline Lender and any other financial institution or other Person that (a) is
listed on the signature pages hereof as a “Lender”, (b) from time to time becomes a party hereto by execution of an Assignment, in each case together with its successors or (c) becomes a party hereto in connection with an
Incremental Term Loan Commitment, Incremental Revolving Credit Commitment, Extended Revolving Credit Commitment, Extended Term Loan Facility, Specified Refinancing Revolving Credit Commitment or Specified Refinancing Term Loan Facility by execution
of an Incremental Amendment, Extension Amendment or Refinancing Amendment, as applicable, in connection with such Incremental Term Loan Commitment, Incremental Revolving Credit Commitment, Extended Revolving Credit Commitment, Extended Term Loan
Facility, Specified Refinancing Revolving Credit Commitment or Specified Refinancing Term Loan Facility. 
 “Letter of
Credit” means any letter of credit Issued pursuant to Section 2.4. 
 “Liabilities” means all claims,
actions, suits, judgments, damages, losses, liability, obligations, fines, penalties, sanctions, costs, fees, taxes, commissions, charges, disbursements and expenses, in each case of any kind or nature (including interest accrued thereon or as a
result thereof and fees, charges and disbursements of financial, legal and other advisors and consultants), whether joint or several, whether or not indirect, contingent, consequential, actual, punitive, treble or otherwise. 

“Lien” means any mortgage, deed of trust, pledge, hypothecation, assignment for security, charge, security deposit
arrangement, encumbrance, easement, lien (statutory or other), security interest or other similar security arrangement, including any conditional sale contract or other title retention agreement, the interest of a lessor under a Capital Lease and
any synthetic or other financing lease having substantially the same economic effect as any of the foregoing. 

  
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 “Limited Condition Acquisition” means any Permitted Acquisition whose
consummation is not conditioned on the availability of, or on obtaining, third party financing. 
 “Loan” means any loan
made or deemed made by any Lender hereunder. Unless the context shall otherwise require, the term “Loans” also shall include any loans made by any Lenders pursuant to Sections 2.19, 2.22 and 2.23. 

“Loan Documents” means, collectively, this Agreement, any Notes, the Guaranty and Security Agreement, the Mortgages, the
Swiss Pledge Agreement, the Control Agreements, the Fee Letters, the L/C Reimbursement Agreements, the Secured Hedging Agreements, the Secured Treasury Services Agreements, each intercreditor agreement entered into by the Collateral Agent as
may be contemplated hereunder and, when executed, each document executed by a Loan Party and delivered to either Administrative Agent, the Collateral Agent, any Lender or any L/C Issuer in connection with or pursuant to any of the foregoing or the
Obligations, together with any modification of any term, or any waiver with respect to, any of the foregoing. 
 “Loan
Party” means the Borrower and each Guarantor. 
 “Majority Lenders” of any Tranche means those Non-Defaulting
Lenders which would constitute the Required Lenders under, and as defined in, this Agreement if all outstanding Obligations under the other Tranches under this Agreement were repaid in full and all Commitments with respect thereto were terminated.

 “Margin Stock” has the meaning provided in Regulation U of the Federal Reserve Board. 

“Material Adverse Effect” means an effect that results in or causes, or could reasonably be expected to result in or cause, a
material adverse change in any of (a) the condition (financial or otherwise), business, performance, operations or property of the Group Members, taken as a whole, (b) the ability of the Loan Parties, taken as a whole, to perform their
obligations under any Loan Document and (c) the validity or enforceability of any Loan Document or the rights and remedies of the Administrative Agents, the Collateral Agent, the Lenders and the other Secured Parties under any Loan Document.

 “Maturity Date” means, with respect to the relevant Tranche of Loans, the Scheduled A Term Loan Maturity Date, the
Scheduled B Term Loan Maturity Date, the Scheduled Revolving Credit Termination Date or the applicable Incremental Term Loan Maturity Date, as the case may be; provided, however, that with respect to (i) any Tranche of Specified
Refinancing Term Loans and/or Specified Refinancing Revolving Credit Commitments, the Maturity Date with respect thereto shall be as specified in the applicable Refinancing Amendment and (ii) any Tranche of Extended Term Loans and/or Extended
Revolving Credit Commitments, the Maturity Date with respect thereto instead shall be as specified in the applicable Extension Amendment. 

“Maximum Lawful Rate” has the meaning specified in Section 2.9(d). 

“Moody’s” means Moody’s Investors Service, Inc. 

“Mortgage” means any mortgage, deed of trust or other document executed or required herein to be executed by any Loan Party
and granting a security interest over real property in favor of the Collateral Agent as security for the Obligations. 

  
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 “Mortgage Supporting Documents” means, with respect to any Mortgage for a parcel
of owned real property, each document (including (i) title insurance policies or marked-up unconditional insurance binders (in each case, together with copies of all documents referred to therein), (ii) ALTA (or TLTA, if applicable)
as-built surveys (in form and as to date that is sufficiently acceptable to the title insurer issuing title insurance to the Collateral Agent for such title insurer to deliver endorsements to such title insurance as reasonably requested by the
Collateral Agent), (iii) environmental assessments and reports, (iv) evidence regarding recording and payment of fees, insurance premium and taxes, (v) “life of loan” Federal Emergency Management Agency Standard Flood Hazard
Determinations with respect to each real property covered by a Mortgage, in form and substance reasonably acceptable to the Collateral Agent (together with notice about special flood hazard area status and flood disaster assistance, duly executed by
the applicable Loan Party, and evidence of flood insurance, in the event any improved parcel of real property or a portion thereof is located in a special flood hazard area) and (vi) any estoppels, assignments, subordination agreements and
other additional documentation, information and certifications, in each of the foregoing cases that the Collateral Agent may reasonably request, to create, register, perfect, maintain, evidence the existence, substance, form or validity of or
enforce a valid lien on and perfected security interest in such parcel of real property in favor of the Collateral Agent for the benefit of the Secured Parties, subject only to Permitted Liens or other Liens as the Collateral Agent may approve
(provided that such approval shall not be unreasonably withheld if such other Lien is affirmatively insured under a lender’s title insurance policy). 

“Multiemployer Plan” means any multiemployer plan, as defined in Section 400l(a)(3) of ERISA, to which any ERISA
Affiliate contributes to or has contributed to within the last 6 years or otherwise has any obligation or liability, contingent or otherwise. 

“Net Cash Proceeds” means proceeds received in cash from (a) any Sale of, or Property Loss Event with
respect to, property, net of (i) the out-of-pocket cash costs, fees and expenses paid or required to be paid in connection therewith, (ii) taxes paid or reasonably estimated to be payable as a result thereof, (iii) any amount required
to be paid or prepaid on Indebtedness (other than the Obligations, any secured Permitted Additional Debt and Indebtedness owing to any Group Member) secured by the property subject thereto and (iv) in the case of a Sale of any property, the
amount of liabilities not assumed by the buyer (not constituting Indebtedness) reasonably estimated by the Borrower to be payable by the Borrower or a Subsidiary as a result thereof at the time of, or within 180 days after the date of, such Sale or
(b) any incurrence of Indebtedness or (solely for purposes of the last paragraph of Section 8.3) issuance of any Stock, in each case net of brokers’, advisors’, arrangers’ and investment banking fees and other out-of-pocket underwriting discounts, commissions and other out-of-pocket cash costs, fees and expenses, in each case incurred in connection with such transaction; provided, however, that any such
proceeds received by any Subsidiary of the Borrower that is not a Wholly Owned Subsidiary of the Borrower shall constitute “Net Cash Proceeds” only to the extent of the aggregate direct and indirect beneficial ownership interest of
the Borrower therein. 
 “New 2023 Subordinated Notes” means the 6.375% unsecured senior subordinated notes due 2023, to be
issued by the Borrower pursuant to the New 2023 Subordinated Notes Indenture, in an aggregate principal amount of $425,000,000 (as such amount may be reduced by any repayments, prepayments, redemptions, repurchases, sinking fund or similar payments
of principal thereof). 

  
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 “New 2023 Subordinated Notes Indenture” means the Indenture to be entered into
in respect of the New 2023 Subordinated between the Borrower, as issuer, and U.S. Bank National Association, as trustee, reflecting the terms and conditions of the New 2023 Subordinated Notes substantially as set forth in the Offering Memorandum
related thereto dated June 11, 2015, as the same may be amended, modified or supplemented from time to time in accordance with the terms hereof and thereof. 

“New Lender” has the meaning specified in Section 2.19(b). 

“Non-Defaulting Lender” means and includes each Lender which is not a Defaulting Lender. 

“Non-Funding Lender” has the meaning specified in Section 2.2(c). 

“Non-U.S. Lender Party” means each of each Administrative Agent, each Lender, each L/C Issuer, each SPV and each participant,
in each case that is not a Domestic Person. 
 “Note” means a promissory note of the Borrower, in substantially the form of
Exhibit B-1, B-2, B-3 or B-4, as applicable (and, in the case of any Extended Term Loan Facility, Extended Revolving Credit Facility, Specified Refinancing Term Loan Facility and Specified Refinancing Revolving
Credit Facility, any promissory note of the Borrower substantially similar in form to Exhibit B-1, B-2, B-3 or B-4, as applicable), payable to a Lender or its registered
assigns in any Facility in a principal amount equal to the amount of such Lender’s Commitment under such Facility (or, in the case of the Term Loan Facility, the aggregate initial principal amount of the Term Loans made by such Lender). 

“Notice of Borrowing” has the meaning specified in Section 2.2. 

“Notice of Conversion or Continuation” has the meaning specified in Section 2.10(b). 

“Obligations” means, with respect to any Loan Party, all amounts, obligations, liabilities, covenants and duties of every
type and description owing by such Loan Party to any Administrative Agent, the Collateral Agent, any Lender, any L/C Issuer, any other Indemnitee, any participant, any SPV, any Secured Hedging Counterparty or any Secured Treasury Services Creditor
arising out of, under, or in connection with, any Loan Document, whether direct or indirect (regardless of whether acquired by assignment), absolute or contingent, due or to become due, whether liquidated or not, now existing or hereafter arising
and however acquired, and whether or not evidenced by any instrument or for the payment of money, including, without duplication, (a) if such Loan Party is the Borrower, all Loans and L/C Obligations, (b) all interest, whether or not
accruing after the filing of any petition in bankruptcy or after the commencement of any insolvency, reorganization or similar proceeding, and whether or not a claim for post-filing or post-petition interest is allowed in any such proceeding, and
(c) all other fees, expenses (including reasonable fees, charges and disbursement of counsel), interest, premiums, commissions, charges, costs, disbursements, indemnities and reimbursement of amounts paid and other sums chargeable to such Loan
Party pursuant to any Loan Document (including those payable to L/C Issuers as described in Section 2.11). 

“OFAC” has the meaning specified in the definition of “Sanctions Laws and Regulations.” 

  
 30 

 “Other Taxes” has the meaning specified in Section 2.17(c). 

“P&G Call Option” means the ability of a member of the P&G JV Companies to require a breaching member (or any of its
affiliates) to sell its units or shares in the P&G JV Companies (less damages arising from the material breach) to the non-breaching member (or any of its affiliates) pursuant to the P&G JV Agreements. 

“P&G Holdings Guaranty” means that certain guaranty dated May 17, 2007 made by the Borrower in respect of the
P&G Joint Venture. 
 “P&G Joint Venture” means the joint venture between the Borrower and The Proctor &
Gamble Company conducted through the P&G JV Companies pursuant to the P&G JV Agreements for the purpose of developing, acquiring and marketing consumer diagnostic and monitoring products (excluding products in the cardiology, diabetes and
oral care fields). 
 “P&G JV Agreements” means the agreements set forth on Schedule 4.3(b). 

“P&G JV Capital Call Obligations” means any capital call obligation of the P&G JV Companies under the P&G JV
Agreements, or any guaranty thereof by the Borrower pursuant to the P&G Holdings Guaranty. 
 “P&G JV Companies”
means US CD LLC, a Delaware limited liability company, and SPD Swiss Precision Diagnostics GmbH, a company organized under the laws of Switzerland and any subsidiaries of either of them. 

“Participant Register” has the meaning specified in Section 11.2(f). 

“Patents” means all right, title and interest (and all related IP Ancillary Rights) arising under any Requirement of Law in
or relating to patents and applications therefor. 
 “Patriot Act” means USA PATRIOT Act (Title III of Pub. L. 107-56
(signed into law October 26, 2001). 
 “PBGC” means the United States Pension Benefit Guaranty Corporation and any
successor thereto. 
 “Pension Plan” means a Plan described in Section 3(2) of ERISA 

“Permit” means, with respect to any Person, any permit, approval, authorization, license, registration, certificate,
concession, grant, franchise, variance, permission, clearance, notice of no objection or waiver from, and any other Contractual Obligations in the nature of any of the foregoing with, any Governmental Authority, in each case whether or not having
the force of law, and applicable to or binding upon such Person or any of its property or to which such Person or any of its property is subject. 

“Permitted Acquisition” means any Proposed Acquisition satisfying each of the following conditions: (a) except with
respect to any Proposed Acquisition having Permitted Acquisition Consideration of less than $25,000,000, the Administrative Agents shall have received reasonable advance notice of such Proposed Acquisition including a reasonably detailed description
thereof at least 10 days prior to the consummation of such Proposed Acquisition (or such later date as 

  
 31 

 
may be agreed by the Administrative Agents) and on or prior to the date of such Proposed Acquisition, the Administrative Agents shall have received copies of the acquisition agreement and related
material Contractual Obligations and other material documents and information (including financial information and analysis, environmental assessments and reports, opinions, certificates and lien searches), in each of the foregoing cases as
reasonably requested by either Administrative Agent, (b) as of the date of consummation of any transaction as part of such Proposed Acquisition and after giving effect to all transactions to occur on such date as part of such Proposed
Acquisition, no Default or Event of Default shall be continuing, (c) after giving effect to such Proposed Acquisition, the Borrower shall be in compliance with the financial covenant set forth in Article V (but assuming for the
purpose of such compliance with the maximum Consolidated Secured Leverage Ratio set forth in Section 5.1, that the maximum Consolidated Secured Leverage Ratio permitted at such time was 4.25:1.00) on a Pro Forma Basis as of the last day
of the last Fiscal Quarter for which Financial Statements have been delivered hereunder for the four Fiscal Quarter period ending on such day (as if such Permitted Acquisition had occurred on the first day of such period) and (d) at or prior to
the closing of such Proposed Acquisition, the Borrower shall deliver to the Administrative Agents a certificate of the chief financial officer, treasurer or vice president, finance of the Borrower to the effect that the conditions in clauses
(b) and (c) above have been satisfied and setting forth the calculation thereof, which certificate shall be a form reasonably satisfactory to the Administrative Agents (provided that no such certificate shall be required
for any Proposed Acquisition having Permitted Acquisition Consideration of less than $25,000,000). For purposes of preceding clauses (a) and (d), to the extent that any Permitted Acquisition Consideration is in the form of an
earn-out or other deferred payment obligation that is to be paid over time or from time to time, only the aggregate amount thereof that is reasonably estimated to be paid by the Borrower or its Subsidiary in connection with such Permitted
Acquisition (as determined in good faith by a Responsible Officer of the Borrower) shall be included in the calculation of the aggregate amount of the Permitted Acquisition Consideration for such Permitted Acquisition for purposes of determining
whether the notice and officer’s certificate referred to in preceding clauses (a) and (d) need to be delivered. “Permitted Acquisition” also includes any proposed merger or acquisition consented to by
the Required Lenders to be treated as a Permitted Acquisition hereunder. 
 “Permitted Acquisition Consideration” means the
aggregate amounts payable in connection with, and other consideration for, any Permitted Acquisition, in each case, including, if and when earned, any “earnout” and similar payment obligations, all transaction costs and all Indebtedness,
liabilities and Guaranty Obligations incurred or assumed in connection therewith or otherwise reflected in a Consolidated balance sheet of the Borrower and the Proposed Acquisition Target. 

“Permitted Acquisition Debt” means Indebtedness which satisfies each of the following conditions: (a) the Indebtedness
is either (i) unsecured Indebtedness of the Borrower or any of its Subsidiaries that is issued or incurred to any seller or sellers (or any shareholder(s), affiliate(s), designee(s), successor(s) and/or assign(s) thereof) or otherwise as
consideration pursuant to the terms of a Permitted Acquisition and/or (ii) Indebtedness assumed in connection with any Permitted Acquisition (but not incurred in connection with or contemplation of such Permitted Acquisition), (b) except
in respect of any Permitted Acquisition Debt incurred, issued or assumed in connection with any Proposed Acquisition having Permitted Acquisition Consideration of less than $25,000,000, the Administrative Agents shall have received reasonable
advance notice of the incurrence, issuance and/or assumption of such Indebtedness including a reasonably detailed description thereof at least 10 days prior to such incurrence, issuance and/or assumption (or such

  
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later date as may be agreed by the Administrative Agents) and on or prior to the date of such incurrence, issuance and/or assumption, the Administrative Agents shall have received copies of the
credit agreement, indenture and related Contractual Obligations and other documents and information, in each of the foregoing cases as reasonably requested by either Administrative Agent, (c) as of the date of incurrence, issuance and/or
assumption of such Indebtedness and after giving effect to all transactions to occur on such date (including such Permitted Acquisition), no Default or Event of Default shall be continuing, (d) after giving effect to the incurrence, issuance
and/or assumption of such Indebtedness and such Permitted Acquisition, the Borrower shall be in compliance with (x) a Consolidated Secured Leverage Ratio of no greater than 4.00:1.00 and (y) a Consolidated Total Leverage Ratio of no
greater than 5.75:1.00, in the case of the preceding clauses (x) and (y), on a Pro Forma Basis as of the last day of the last Fiscal Quarter for which Financial Statements have been delivered hereunder for the four Fiscal Quarter period ending
on such day (as if such Indebtedness had been incurred, issued or assumed and such Permitted Acquisition had occurred on the first day of such period), and (e) at or prior to the incurrence, issuance and/or assumption of such Indebtedness (or
at such later time as the Administrative Agents may approve), the Borrower shall deliver to the Administrative Agents a certificate of the chief financial officer, treasurer or vice president, finance of the Borrower to the effect that the
conditions in clauses (c) and (d) above have been satisfied and setting forth in reasonable detail the calculation thereof, which certificate shall be in a form reasonably satisfactory to the Administrative Agents
(provided that no such certificate shall be required for any Permitted Acquisition Debt being incurred or issued to finance any Proposed Acquisition having Permitted Acquisition Consideration of less than $25,000,000); provided that
only one certificate shall be required for Permitted Acquisition Debt that may be incurred or issued in multiple tranches over time and from time to time in accordance with the obligations or commitments existing in the transaction documents for
such Permitted Acquisition Debt and the related Permitted Acquisition at the time of the closing of such Permitted Acquisition (such certificate to be delivered at or prior to the time of the first incurrence or issuance of such Permitted
Acquisition Debt or such later time as the Administrative Agents may agree). For purposes of (i) preceding clauses (c) and (d), to the extent that any Permitted Acquisition Debt is to be incurred or issued over time or from
time to time, the full amount of all such Permitted Acquisition Debt shall be deemed incurred and/or issued at the time of the initial incurrence or issuance thereof (and to the extent that any portion of such Permitted Acquisition Debt constitutes
any deferred payment obligation incurred or to be incurred in reliance on clause (a)(i) above, the amount thereof for the purposes of such calculation shall be the amount certified by a Responsible Officer of the Borrower as being the maximum
amount reasonably expected to be payable in connection therewith and (ii) preceding clauses (b) and (e), to the extent that any Permitted Acquisition Consideration is in the form of an earn-out or other deferred payment
obligation that is to be paid over time or from time to time, only the aggregate amount thereof that is reasonably estimated to be paid by the Borrower or its Subsidiary in connection with such Permitted Acquisition (as determined in good faith by a
Responsible Officer of the Borrower) shall be included in the calculation of the aggregate amount of the Permitted Acquisition Consideration for such Permitted Acquisition for purposes of determining whether the notice and officer’s certificate
referred to in preceding clauses (b) and (e) need to be delivered). 
 “Permitted Additional
Debt” means Indebtedness (which Indebtedness may be (i) (x) senior (i.e. pari passu in right of payment with the Loans) or (y) Subordinated Debt and (ii) (x) unsecured or (y) in the case of senior
Indebtedness only, secured by a Lien ranking pari passu with, or junior to, the Lien securing the Obligations, in each case issued or incurred by the Borrower), the terms of which Indebtedness satisfy each of the following conditions:
(a) except 

  
 33 

 
with respect to Permitted Additional Debt of less than $10,000,000, the Administrative Agents shall have received reasonable advance notice of the incurrence or issuance of such Indebtedness
including a reasonably detailed description thereof at least 10 days prior to such incurrence or issuance (or such later date as may be agreed by the Administrative Agents) and on or prior to the date of such incurrence or issuance, the
Administrative Agents shall have received copies of any related loan agreement, indenture or other instrument evidencing such Indebtedness and related Contractual Obligations and other documents and information, in each of the foregoing cases as
reasonably requested by either Administrative Agent, (b) such Indebtedness shall not be subject to any scheduled amortization, mandatory redemption, mandatory repayment or mandatory prepayment, sinking fund or similar payment (other than, in
each case, (x) customary offers to repurchase upon a change of control, asset sale or event of loss and acceleration rights after an event of default, (y) any such amortization, redemption, repayment, sinking fund or other payment at the
sole option of the Borrower, and (z) in the case of Indebtedness that is convertible into shares of the Borrower’s Stock, customary repurchase obligations in connection with a “Fundamental Change” or “Termination of
Trading” or any term of similar effect, as defined in any documents relating to such Indebtedness) or have a final maturity date, in either case prior to the date occurring 180 days following the Latest Maturity Date in effect at the time of
the incurrence or issuance of such Indebtedness, (c) the loan agreement, indenture or other applicable instrument or agreement governing such Indebtedness (including any related guaranties and collateral) shall not include any “financial
maintenance covenants” (whether stated as a covenant, default or otherwise, although “incurrence-based” financial tests may be included), (d) if such Indebtedness is Subordinated Debt, it satisfies the requirements set forth in
the definition of “Subordinated Debt”, (e) as of the date of incurrence or issuance of such Indebtedness and after giving effect to all transactions to occur on such date, no Default or Event of Default is continuing,
(f) such Indebtedness, if secured on a ratable basis with the Loans, does not provide for any mandatory repayment or redemption from asset sales or casualty or condemnation events on more than a ratable basis with the Loans, (g) such
Indebtedness, (x) if secured, shall not be secured by any Lien on any asset of the Borrower or any of its Subsidiaries other than Collateral, (y) if guaranteed, shall not be guaranteed by any Group Member other than the Guarantors, and
(z) if secured on a pari passu basis with the Obligations, shall be in the form of debt securities (and not loans), (h) the holders of such Indebtedness (or the respective agent or trustee on their behalf), if such Indebtedness is secured,
shall have entered into an intercreditor agreement with the Collateral Agent in form and substance reasonably satisfactory to the Administrative Agents, (i) the Borrower shall be in compliance with (x) a Consolidated Secured Leverage Ratio
of no greater than 4.00:1.00 and (y) a Consolidated Total Leverage Ratio of no greater than 5.75:1.00, in the case of the preceding clauses (x) and (y), on a Pro Forma Basis as of the last day of the last Fiscal Quarter for which Financial
Statements have been delivered hereunder for the four Fiscal Quarter period ending on such day (as if such Indebtedness had been incurred or issued on the first day of such period), and (j) at or prior to the incurrence and/or issuance of
such Indebtedness (or at such later time as the Administrative Agents may approve), the Borrower shall deliver to the Administrative Agents a certificate of its chief financial officer, treasurer or vice president, finance to the effect that
the conditions in clause (i) above have been satisfied and setting forth in reasonable detail the calculation thereof, which certificate shall be in a form reasonably satisfactory to the Administrative Agents (provided that no
such certificate shall be required for Permitted Additional Debt of less than $10,000,000). 
 “Permitted Additional Debt
Documents” means, on and after the execution and delivery thereof by any Group Member, each note, instrument, agreement, guaranty, security agreement, mortgage and other document relating to each incurrence or issuance of Permitted
Additional Debt, as the same may be amended, modified and/or supplemented from time to time in accordance with the terms hereof and thereof. 

  
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 “Permitted Indebtedness” means any Indebtedness of any Group Member that is not
prohibited by Section 8.1. 
 “Permitted Investment” means any Investment of any Group Member that is not
prohibited by Section 8.3. 
 “Permitted Lien” means any Lien on or with respect to the property of any Group
Member that is not prohibited by Section 8.2. 
 “Permitted Refinancing” means Indebtedness (including Guaranty
Obligations of Group Members in respect thereof) constituting a refinancing, extension of maturity or other modifications of the terms of (including Indebtedness issued in exchange for) Permitted Indebtedness to the extent provided for in
Section 8.1 (including any Permitted Refinancing of any such Permitted Refinancing Indebtedness) (a) that has an aggregate outstanding principal amount not greater than the aggregate principal amount of such Permitted Indebtedness
being refinanced or extended (plus accrued and unpaid interest and premium payable on the Permitted Indebtedness being refinanced and the aggregate amount of all fees, costs and expenses incurred in connection with such Permitted Refinancing
(including advisor, professional and investment banking fees, arranger fees, underwriting fees, tender offer premiums and/or fees, and consent and/or amendment fees)) outstanding at the time of such refinancing or extension, (b) (i) to the
extent such Indebtedness refinances or extends Permitted Indebtedness (other than Indebtedness represented by the Existing Notes), that has a weighted average maturity (measured as of the date of such refinancing or extension) no shorter than that
of such Permitted Indebtedness being refinanced or extended (as of the date immediately prior to such refinancing or extension) and (ii) to the extent such Indebtedness refinances or extends Permitted Indebtedness represented by the Existing
Notes, that is not subject to any scheduled amortization, mandatory redemption, mandatory repayment or mandatory prepayment, sinking fund or similar payment (other than, in each case, (x) customary offers to repurchase upon a change of control,
asset sale or event of loss and acceleration rights after an event of default, (y) any of the foregoing at the sole option of the Borrower, and (z) in the case of Indebtedness that is convertible into shares of the Borrower’s Stock,
customary repurchase obligations in connection with a “Fundamental Change” or “Termination of Trading” or any term of similar effect, as defined in any documents relating to such Indebtedness) or have a final maturity date, in
either case prior to the date occurring 180 days following the Latest Maturity Date in effect at the time of the incurrence or issuance of such Indebtedness, (c) that is not secured by any property or any Lien other than those securing such
Permitted Indebtedness being refinanced or extended; provided such Lien shall have the same (or a more junior) priority as the Lien securing such Permitted Indebtedness being refinanced or extended, (d) that is subordinated to the
Obligations on terms no less favorable (in the reasonable judgment of the Administrative Agents) to the holders of the Obligations as the Permitted Indebtedness being refinanced or extended, (e) (i) to the extent such Indebtedness
refinances or extends any Permitted Indebtedness that includes any “financial maintenance covenants”, that does not include any additional or new “financial maintenance covenants” or make existing “financial maintenance
covenants” more restrictive in any material respect and (ii) to the extent that such indebtedness refinances or extends any Permitted Indebtedness that does not include any “financial maintenance covenants”, that does not include
any “financial maintenance covenants” and (f) does not benefit from any Guaranty Obligation other than any Guaranty Obligation benefitting such Permitted Indebtedness being refinanced or extended immediately

  
 35 

 
prior to such refinancing or extension. Notwithstanding anything to the contrary contained herein, the incurrences of Indebtedness in respect of the New 2023 Subordinated Notes pursuant to, and
in accordance with, Section 8.1(q) shall be deemed to be a Permitted Refinancing of the Existing 2018 Subordinated Notes. 

“Permitted Reinvestment” means, with respect to the Net Cash Proceeds of any Sale or Property Loss Event, to acquire (or make
Capital Expenditures to finance the acquisition, repair, improvement or construction of), to the extent otherwise permitted hereunder, property useful in the business of the Borrower or any of its Subsidiaries (including through a Permitted
Acquisition) or, if such Property Loss Event involves loss or damage to property, to repair such loss or damage. 
 “Permitted Stock
Repurchases” means, subject to Section 8.5(e)(i), any repurchase, redemption, retirement, termination, defeasance, cancellation or other purchase by the Borrower of Stock or Stock Equivalents of the Borrower on or after the
Closing Date satisfying each of the following conditions: (a) as of the date of consummation of any such repurchase, redemption, retirement or other purchase and after giving effect thereto on such date, no Default or Event of Default shall be
continuing, (b) both immediately before and immediately after giving effect to such repurchase, redemption, retirement, termination, defeasance, cancellation or other purchase, the sum of (I) Revolver Availability and (II) the aggregate
amount of Unrestricted cash and Cash Equivalents of the Loan Parties shall be at least $150,000,000 and (c) the aggregate consideration paid by the Group Members for all such repurchases, redemptions, retirements, terminations, defeasances,
cancellations or other purchases, without duplication, on or after the Closing Date shall not exceed $300,000,000. 

“Person” means any individual, partnership, corporation (including a business trust and a public benefit corporation), joint
stock company, estate, association, firm, enterprise, trust, limited liability company, unincorporated association, joint venture and any other entity or Governmental Authority. 

“Platform” has the meaning specified in Section 11.20(a). 

“Preferred Stock”, as applied to the Stock of any Person, means Stock of such Person (other than common Stock of such Person)
of any class or classes (however designed) that ranks prior, as to the payment of dividends or as to the distribution of assets upon any voluntary or involuntary liquidation, dissolution or winding up of such Person, to shares of Stock of any other
class of such Person, and shall include any Disqualified Stock. 
 “Pro Forma Administrative Agent” has the meaning
specified in the preamble hereto. 
 “Pro Forma Basis” means, in connection with any calculation of compliance with any
financial covenant ratio or financial term as it relates to any determination for any period and any Pro Forma Transaction, that such determination shall be made by giving pro forma effect to each such Pro Forma Transaction after the
first day of the relevant period (including, in the case of any Permitted Acquisition, any Pro Forma Cost Savings directly attributable to such Pro Forma Transaction and, in the case of the incurrence of any Indebtedness, assuming that the proceeds
thereof are applied), as if each such Pro Forma Transaction had been consummated on the first day of such period, and (i) in connection with any Permitted Acquisition or Sale based on historical results accounted for in accordance with GAAP and
(ii) to the extent applicable in connection with any Permitted Acquisition, based on reasonable assumptions that are specified in 

  
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detail in the relevant Compliance Certificate, Financial Statement or other document provided to the Administrative Agents or any Lender in connection herewith in accordance with Regulation S-X
(except for any Pro Forma Cost Savings which need not be in accordance with Regulation S-X). 
 “Pro Forma Cost Savings”
means, with respect to any period and in connection with any Permitted Acquisition, operating expense reductions that are reasonably expected to be sustainable over such period, will not adversely affect revenues and are not greater than the
reduction reasonably expected to be realized, regardless of whether these cost savings could then be reflected in pro forma financial statements in accordance with Regulation S-X, all such operating expense reductions to be reasonably determined in
good faith by the chief financial or accounting officer of the Borrower and, to the extent requested by either Administrative Agent, to be set forth in a certificate signed by such officer. 

“Pro Forma Transaction” means, as the context requires, (i) any transaction consummated as part of any Permitted
Acquisition, together with each other transaction relating thereto and consummated in connection therewith, (ii) the incurrence of any Indebtedness (other than revolving Indebtedness, except to the extent such Indebtedness is incurred to
refinance or repay other outstanding Indebtedness (including a Restricted Debt Payment) or to finance a Permitted Acquisition, an Investment or a Restricted Payment), (iii) the purchase of any Indebtedness in accordance with the procedures set
forth in Section 2.21 or the permanent repayment of any Indebtedness (including a Restricted Debt Payment) (other than revolving Indebtedness, except to the extent accompanied by a corresponding permanent commitment reduction),
(iv) any Sale permitted under Section 8.4(e), (f), (g), (h) or (i) together with each other transaction relating thereto and consummated in connection therewith, (v) any Restricted Payment
made (x) in respect of a Permitted Stock Repurchase in accordance with Section 8.5(e), (y) in respect of any cash dividend on any common Stock or Preferred Stock of the Borrower made in accordance with
Section 8.5(f), or (z) in respect of any Restricted Payment made in accordance with Section 8.5(h), (vi) any Investment made in accordance with Section 8.3(m) and (vii) any designation of a
Subsidiary as an Unrestricted Subsidiary or an Unrestricted Subsidiary as a Subsidiary, in either case, pursuant to Section 7.15. 

“Pro Rata Administrative Agent” has the meaning specified in the preamble hereto. 

“Pro Rata Commitments” means those Commitments related to the respective Facilities included in any determination of the
Required Pro Rata Lenders. 
 “Pro Rata Loans” means those Loans and Letters of Credit related to the respective Facilities
included in any determination of the Required Pro Rata Lenders. 
 “Pro Rata Outstandings” of any Lender at any time, means
(a) in the case of any Term Loan Facility, the outstanding principal amount of the Term Loans owing to such Lender under such Term Loan Facility and (b) in the case of any Revolving Credit Facility, the sum of (i) the outstanding
principal amount of Revolving Loans owing to such Lender under such Revolving Credit Facility and (ii) the amount of the participation of such Lender in the L/C Obligations outstanding with respect to all Letters of Credit. 

“Pro Rata Share” means, with respect to any Lender and any Facility or Facilities, as the case may be, at any time, the
percentage obtained by dividing (a) the sum of the Commitments (or, if such Commitments in any such Facility are terminated, the Pro Rata Outstandings therein) 

  
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of such Lender then in effect under such Facility or Facilities, as the case may be, by (b) the sum of the Commitments (or, if such Commitments in any such Facility are terminated, the Pro
Rata Outstandings therein) of all Lenders then in effect under such Facility or Facilities, as the case may be; provided, however, that, if there are no Commitments and no Pro Rata Outstandings in any of such Facility or Facilities, as
the case may be, such Lender’s Pro Rata Share in such Facility or Facilities shall be determined based on the Pro Rata Share in such Facility or Facilities, as the case may be, most recently in effect, after giving effect to any subsequent
assignment and any subsequent non-pro rata payments of any Lender pursuant to Section 2.18. 
 “Projections”
means, collectively, the Initial Projections and any document delivered pursuant to Section 6.1(e). 
 “Property Loss
Event” means, with respect to any property, any loss of or damage to such property or any taking of such property or condemnation thereof. 

“Proposed Acquisition” means (a) any proposed acquisition that is consensual and approved by the board of directors (or
other applicable governing body) of the applicable Proposed Acquisition Target, of (x) (i) in the case of a Proposed Acquisition Target that is to become a Loan Party, at least a majority of the Stock of such Proposed Acquisition Target or
(ii) in the case of a Proposed Acquisition Target that is not to become a Loan Party, at least 75% (or to the extent provided below in this definition, at least a majority) of the Stock of such Proposed Acquisition Target, in each case by the
Borrower or any Subsidiary of the Borrower or (y) all or substantially all of the assets of any Proposed Acquisition Target by any Subsidiary of the Borrower, (b) any proposed merger of any Proposed Acquisition Target with or into the
Borrower or any Subsidiary of the Borrower (and, in the case of a merger with (x) the Borrower, with the Borrower being the surviving corporation, and (y) another Loan Party, with a Loan Party being the surviving Person (which, subject to
the satisfaction of the requirements set forth in Section 7.10 within the time periods set forth therein, may include the Proposed Acquisition Target being the surviving Person and becoming a Loan Party)), (c) any proposed acquisition of
all or any portion of the remaining Stock and/or Stock Equivalents of any Subsidiary of the Borrower that is not a Wholly Owned Subsidiary; provided that in the case where such Subsidiary is not, and will not become, a Loan Party after such
acquisition, the Borrower and its Subsidiaries must own at least 75% (or to the extent provided below in this definition, at least a majority) of the Stock of such Proposed Acquisition Target after such acquisition, or (d) any proposed
acquisition of all or any portion of the remaining Stock and/or Stock Equivalents in any Proposed Acquisition Target that is not already owned by the Borrower or any Subsidiary of the Borrower, provided that (i) in the case of a Proposed
Acquisition Target that is to become a Loan Party after such acquisition, the Borrower and its Subsidiaries must own at least a majority of the Stock of such Proposed Acquisition Target after such acquisition or (ii) in the case of a Proposed
Acquisition Target that is not to become a Loan Party after such acquisition, the Borrower and its Wholly Owned Subsidiaries must own at least 75% (or to the extent provided below in this definition, at least a majority) of the Stock of such
Proposed Acquisition Target after such acquisition. With respect to any Proposed Acquisition of a Proposed Acquisition Target that is not to become a Loan Party after such acquisition, the 75% threshold set forth above in this definition may be
reduced to a majority threshold so long as the aggregate Permitted Acquisition Consideration for all such Proposed Acquisitions does not exceed $100,000,000. 

“Proposed Acquisition Target” means any Person (including any Subsidiary thereof) or any brand, line of business, division,
branch, operating division or other unit operation of any Person. 

  
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 “Public Lender” has the meaning specified in Section 11.20(a). 

“Refinancing” means the refinancing transactions specified in Section 3.1(c)(i). 

“Refinancing Amendment” means an amendment to this Agreement, in form and substance reasonably satisfactory to the
Administrative Agents, among the Borrower, the Administrative Agents and the Lenders providing Specified Refinancing Term Loans or Specified Refinancing Revolving Credit Commitments, which Refinancing Amendment shall effect the incurrence of such
Specified Refinancing Term Loans or Specified Refinancing Revolving Credit Commitments in accordance with Section 2.22. 

“Register” has the meaning specified in Section 2.14(b). 

“Regulation S-X” means Regulation S-X of the Securities Act of 1933. 

“Reinvestment Prepayment Amount” means, with respect to any Net Cash Proceeds on the Reinvestment Prepayment Date therefor,
the amount of such Net Cash Proceeds less any amount paid or required to be paid by any Group Member to make Permitted Reinvestments with such Net Cash Proceeds pursuant to a Contractual Obligation entered into prior to such Reinvestment
Prepayment Date with any Person that is not an Affiliate of the Borrower. 
 “Reinvestment Prepayment Date” means, with
respect to any portion of any Net Cash Proceeds of any Sale or Property Loss Event, the earliest of (a) the 360th day after the completion of the portion of such Sale or Property Loss Event
corresponding to such Net Cash Proceeds, (b) the date that is 5 Business Days after the date on which the Borrower shall have notified the Administrative Agents of the Borrower’s determination not to make Permitted Reinvestments with such
Net Cash Proceeds, and (c) 5 Business Days after the delivery of a notice by both Administrative Agents or the Required Lenders to the Borrower during the continuance of any Event of Default. 

“Related Person” means, with respect to any Person, each Affiliate of such Person and each director, officer, employee,
stockholder, partner or other equity holder, financing source or agent, trustee, representative, attorney, accountant and each insurance, environmental, legal, financial and other advisor (including those retained in connection with the satisfaction
or attempted satisfaction of any condition set forth in Article III) and other consultants and agents of or to such Person or any of its Affiliates, together with, if such Person is the Administrative Agent, each other Person or
individual designated, nominated or otherwise mandated by or helping the Administrative Agent pursuant to and in accordance with Section 10.4 or any comparable provision of any Loan Document. 

“Release” means any release, threatened release, spill, emission, leaking, pumping, pouring, emitting, emptying, escape,
injection, deposit, disposal, discharge, dispersal, dumping, leaching or migration of Hazardous Material into or through the environment. 

“Remedial Action” means all actions required to (a) clean up, remove, treat or in any other way address any Hazardous
Material in the indoor or outdoor environment, (b) prevent or minimize any Release so that a Hazardous Material does not migrate or endanger or threaten to endanger public health or welfare or the indoor or outdoor environment or
(c) perform pre-remedial studies and investigations and post-remedial monitoring and care with respect to any Hazardous Material. 

  
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 “Repricing Event” means (i) any prepayment or repayment of B Term Loans, in
whole or in part, with the proceeds of, or any conversion of B Term Loans into, any new or replacement tranche of term loans (whether under this Agreement or otherwise) bearing interest with an Effective Yield less than the Effective Yield
applicable to the B Term Loans (as such comparative yields are determined by the B Term Loan Administrative Agent) and (ii) any amendment or other modification or waiver to this Agreement which effectively reduces the Effective Yield (as
determined by the B Term Loan Administrative Agent in its reasonable judgment) applicable to the B Term Loans (and any assignment pursuant to Section 2.18 in connection therewith). Any such determination by the B Term Loan Administrative
Agent as contemplated by the preceding sentence shall be conclusive and binding on the Borrower and all Lenders holding B Term Loans absent manifest error. The B Term Loan Administrative Agent shall not have any liability to any Person with respect
to such determination. 
 “Required B Term Loan Lenders” means, at any time, those Non-Defaulting Lenders which would
constitute the Required Lenders under, and as defined in, this Agreement at such time, but, for this purpose, determined as if there were no outstanding A Term Loans (or related A Term Loan Commitments), Revolving Credit Commitments (or, if such
Commitments are terminated, assuming there are no participations in Swing Loans, no unparticipated portions of Swing Loans and no Outstandings in the Revolving Credit Facility), Extended Term Loans (or related Extended Term Loan Commitments) in
respect of any A Term Loans or Specified Refinancing Loans (or related Specified Refinancing Term Loan Commitments) in respect of any A Term Loans at such time. 

“Required Lenders” means, at any time, Non-Defaulting Lenders having at such time in excess of 50% of the sum of (i) the
aggregate Revolving Credit Commitments (or, if such Commitments are terminated, the sum of the amounts of the participations in Swing Loans, the principal amount of unparticipated portions of the Swing Loans and the Pro Rata Outstandings in the
Revolving Credit Facility) and (ii) the aggregate Term Loan Commitments (or, if such Commitments are terminated, the aggregate Pro Rata Outstandings in the Term Loan Facilities) then in effect, ignoring, in such calculation, any Commitments
(or, if such Commitments are terminated, the Pro Rata Outstandings in any Facility) held by any Defaulting Lender or any Non-Funding Lender. 

“Required Pro Rata Lenders” means, at any time, those Non-Defaulting Lenders which would constitute the Required Lenders
under, and as defined in, this Agreement at such time, but, for this purpose, determined as if there were no outstanding B Term Loans (or related B Term Loan Commitments), Incremental Term Loans (or related Incremental Term Loan Commitments),
Extended Term Loans (or related Extended Term Loan Commitments) in respect of any B Term Loans or Incremental Term Loans or Specified Refinancing Loans (or related Specified Refinancing Term Loan Commitments) in respect of any B Term Loans or
Incremental Term Loans at such time. 
 “Required Revolving Credit Lenders” means, at any time, Non-Defaulting Lenders
having at such time in excess of 50% of the aggregate Revolving Credit Commitments (or, if such Commitments are terminated, the sum of the aggregate amounts of the participations in Swing Loans, the aggregate principal amount of the unparticipated
portions of the Swing Loans and the aggregate Pro Rata Outstandings in the Revolving Credit Facility) then in effect, ignoring, in such calculation, any Revolving Credit Commitments (or, if such Revolving Credit Commitments are terminated, the sum
of the amounts of the participations in Swing Loans, the principal amount of the unparticipated portions of the Swing Loans and the Pro Rata Outstandings in the Revolving Credit Facility) held by any Defaulting Lender or any Non-Funding Lender. 

  
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 “Required Term Loan Lenders” means, at any time, Non-Defaulting Lenders having
at such time in excess of 50% of the aggregate Term Loan Commitments (or, if such Commitments are terminated, the aggregate Pro Rata Outstandings in the Term Loan Facilities) then in effect, ignoring, in such calculation, any Term Loan Commitments
(or, if such Term Loan Commitments are terminated, the Pro Rata Outstandings in the Term Loan Facility) held by any Defaulting Lender or Non-Funding Lender. 

“Requirements of Law” means, with respect to any Person, collectively, the common law and all federal, state, local, foreign,
multinational or international laws, statutes, codes, treaties, standards, rules and regulations, guidelines, ordinances, orders, judgments, writs, injunctions, decrees (including administrative or judicial precedents or authorities) and the
interpretation or administration thereof by, and other determinations, directives, requirements or requests of, any Governmental Authority, in each case whether or not having the force of law, and that are applicable to or binding upon such Person
or any of its property or to which such Person or any of its property is subject, including all Healthcare Laws. 
 “Responsible
Officer” means, with respect to any Person, any of the president, chief executive officer, chief financial officer, vice president for finance, treasurer, assistant treasurer, controller, managing member or general partner of such Person
but, in any event, with respect to financial matters, any such officer that is responsible for preparing the Financial Statements delivered hereunder and, with respect to the Corporate Chart delivered pursuant to Section 6.1(d),
documents delivered on the Closing Date and documents delivered pursuant to Section 7.10, the secretary or assistant secretary of such Person or any other officer responsible for maintaining the corporate and similar records of such
Person. Any certificate or other document required to be delivered hereunder by any Responsible Officer or other officer of any Group Member shall, notwithstanding any language therein to the contrary, be deemed to be delivered on behalf of the
applicable Group Member and not in such person’s individual capacity. 
 “Restricted” means, when referring to cash or
Cash Equivalents of the Borrower or any of its Subsidiaries, that such cash or Cash Equivalents (i) appear (or would be required to appear) as “restricted” on a consolidated balance sheet of the Borrower or of any such Subsidiary
(unless such appearance is related to (x) the Loan Documents or the Liens created thereunder or (y) (A) any secured Permitted Additional Debt Documents or the Liens created thereunder or (B) any documents relating to any secured
Permitted Refinancing of any Permitted Additional Debt, or the Liens created thereunder), (ii) are subject to any Lien in favor of any Person other than (x) the Collateral Agent for the benefit of the Secured Parties and
(y) (A) the holders of any secured Permitted Additional Debt (or any agent or trustee in respect thereof) or (B) the holders of any secured Permitted Refinancing of any Permitted Additional Debt (or any agent or trustee in respect
thereof) or (iii) are not otherwise generally available for use by the Borrower or such Subsidiary. 
 “Restricted Debt
Payment” has the meaning specified in Section 8.6. 
 “Restricted Payment” means (a) any
dividend, return of capital, distribution or any other similar payment or Sale of property for less than fair market value, whether direct or indirect and whether in cash, Securities or other property, in each case to the holders (in their
capacities as such) of any Stock or Stock Equivalent of any Group Member and in respect thereof, in each case 

  
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now or hereafter outstanding, including with respect to a claim for rescission of a Sale of such Stock or Stock Equivalent, and (b) any redemption, retirement, termination, defeasance,
purchase or other acquisition for value, whether direct or indirect, of any Stock or Stock Equivalent of any Group Member, now or hereafter outstanding, and any payment or other transfer setting aside funds for any such redemption, retirement,
termination, purchase or other acquisition, whether directly or indirectly and whether to a sinking fund, a similar fund or otherwise. 

“Retained Excess Cash Flow Amount” means, at any date of determination, an amount equal to (a) the sum of the amounts of
Excess Cash Flow for all periods ending after December 31, 2015 and on or prior to the date of determination for which the amount of Excess Cash Flow shall have been calculated as provided in Section 6.1(c) and with respect to
which any payment required under Section 2.8(a) has been paid, minus (b) the sum at the time of determination of (i) the aggregate amount of prepayments required to be made pursuant to Section 2.8(a)
through the date of determination (whether or not such prepayments are accepted by Lenders) and (ii) the aggregate amount by which the payments required by such Section 2.8(a) have been reduced by operation
of clause (B) thereof. 
 “Return Bid” has the meaning specified in Schedule 2.21. 

“Revolver Availability” means the maximum amount of unused Revolving Credit Commitments that would be available for borrowing
of Revolving Loans if after giving effect to such Revolving Loans, the Borrower would be in compliance with the Consolidated Secured Leverage Ratio covenant set forth in Section 5.1 on a Pro Forma Basis as of the last day of the last
Fiscal Quarter for which Financial Statements have been delivered hereunder for the four Fiscal Quarter period ending on such day (as if the Borrower had incurred such Revolving Loans on the first day of such period). 

“Revolving Credit Commitment” means, with respect to each Revolving Credit Lender, the commitment of such Lender to make
Revolving Loans and acquire interests in other Revolving Credit Outstandings, which commitment is in the amount set forth opposite such Lender’s name on Schedule I under the caption “Revolving Credit Commitment”, as
amended to reflect Assignments and as such amount may be reduced or increased pursuant to this Agreement. In addition, the Revolving Credit Commitment of each Lender shall include any Extended Revolving Credit Commitments and Specified Refinancing
Revolving Credit Commitments of such Lender and shall be increased by the amount of any Incremental Revolving Credit Commitments of such Lender. The aggregate amount of the Revolving Credit Commitments on the Closing Date equals $250,000,000. 

“Revolving Credit Commitment Increase Lender” has the meaning specified in Section 2.19(d). 

“Revolving Credit Facility” means the Revolving Credit Commitments and the provisions herein related to the Revolving Loans,
Swing Loans and Letters of Credit. 
 “Revolving Credit Lender” means each Lender that has a Revolving Credit Commitment,
holds a Revolving Loan or participates in any Swing Loan or Letter of Credit. 
 “Revolving Credit Obligations” means
(i) all Revolving Loans, Swing Loans, L/C Obligations and the Revolving Credit Commitments and (ii) all related Obligations relating to the Indebtedness and Commitments described in preceding clause (i). 

  
 42 

 “Revolving Credit Outstandings” means, at any time, the sum of, in each case to
the extent outstanding at such time, (a) the aggregate principal amount of the Revolving Loans and Swing Loans and (b) the L/C Obligations for all Letters of Credit. 

“Revolving Credit Percentage” of any Revolving Credit Lender at any time means a fraction (expressed as a percentage) the
numerator of which is the Revolving Credit Commitment of such Revolving Credit Lender at such time and the denominator of which is the Total Revolving Credit Commitment at such time; provided that (x) if the Revolving Credit Percentage
of any Revolving Credit Lender is to be determined after the Total Revolving Credit Commitment has been terminated, then the Revolving Credit Percentages of such Revolving Credit Lender shall be determined immediately prior (and without giving
effect) to such termination (but giving effect to assignments made thereafter in accordance with the terms hereof) and (y) in the case of Section 2.20 when a Defaulting Lender shall exist, “Revolving Credit Percentage”
means the percentage of the Total Revolving Credit Commitments (disregarding any Defaulting Lender’s Revolving Credit Commitment) represented by such Lender’s Revolving Credit Commitment. 

“Revolving Credit Termination Date” means the earliest of (a) the Scheduled Revolving Credit Termination Date,
(b) the date of termination of the Revolving Credit Commitments pursuant to Section 2.5 or 9.2 and (c) the date on which the Obligations become due and payable pursuant to Section 9.2. 

“Revolving Loan” has the meaning specified in Section 2.1; provided that, at any time that any Extended
Revolving Credit Commitments, Incremental Revolving Credit Commitments or Specified Refinancing Revolving Credit Commitments have been made available, the Extended Revolving Loans and other revolving loans outstanding in respect thereof also shall
be Revolving Loans. 
 “S&P” means Standard & Poor’s Rating Services. 

“Sale and Leaseback Transaction” means, with respect to any Person (the “obligor”), any Contractual
Obligation or other arrangement with any other Person (the “counterparty”) consisting of a lease by such obligor of any property that, directly or indirectly, has been or is to be Sold by the obligor to such counterparty or to any
other Person to whom funds have been advanced by such counterparty based on a Lien on, or an assignment of, such property or any obligations of such obligor under such lease. 

“Sanctions Laws and Regulations” means (i) any sanctions or requirements imposed by, or based upon the obligations or
authorities set forth in, the Executive Order, the USA PATRIOT Act, the U.S. International Emergency Economic Powers Act (50 U.S.C. §§ 1701 et seq.), the U.S. Trading with the Enemy Act (50 U.S.C. App. §§ 1 et
seq.), the U.S. Syria Accountability and Lebanese Sovereignty Act, the U.S. Comprehensive Iran Sanctions, Accountability, and Divestment Act of 2010 or the Iran Sanctions Act, Section 1245 of the National Defense Authorization Act of 2012, all
as amended, or any of the foreign assets control regulations (including but not limited to 31 C.F.R., Subtitle B, Chapter V, as amended) or any other law, sanctions or executive order relating thereto administered or enforced by the
U.S. Department of the Treasury Office of Foreign Assets Control (“OFAC”) or the U.S. Department of State, and any similar law, sanctions, regulation, or Executive Order enacted in the United States after the date of this Agreement,
(ii) any sanctions or requirements imposed under similar laws or regulations enacted by the United Nations, Her Majesty’s Treasury, the European Union or the United Kingdom and (iii) any similar Requirement of Law of any jurisdiction
other than the United States, the European Union or the United Kingdom, in each case, applicable to the Borrower or any of its Subsidiaries. 

  
 43 

 “Scheduled A Term Loan Maturity Date” means June 18, 2020; provided,
however, in the event that any Existing 2018 Subordinated Notes remain outstanding on April 1, 2018, then the Scheduled A Term Loan Maturity Date instead shall be April 1, 2018 (the “Scheduled A Term Loan Springing Maturity
Date”) (unless either (x) the outstanding obligations under the Existing 2018 Subordinated Notes (including all interest that will accrue thereon until such time as the Existing 2018 Subordinated Notes have been redeemed or repaid in
full in accordance with the terms of the Existing 2018 Subordinated Notes Indenture and the Existing 2018 Subordinated Notes Indenture has been terminated) have been defeased or satisfied and discharged in accordance with the terms of the Existing
Notes Documents with respect to the Existing 2018 Subordinated Notes on such date or (y) cash in an aggregate amount equal to all such outstanding obligations has been deposited as security for the benefit of the Secured Parties in a manner, on
terms and conditions, and pursuant to documentation, in each case reasonably satisfactory to the Administrative Agents (which, in any event, shall require that such cash be deposited in a Cash Collateral Account (subject to the Collateral
Agent’s security interest under the Guaranty and Security Agreement)), which cash can only be accessed by the Borrower for the purpose of paying any remaining scheduled interest payments thereon as and when the same shall become due and payable
and to repay such Existing 2018 Subordinated Notes in full at maturity or in connection with any tender offer for, repurchase of or other satisfaction or repayment of, the Existing 2018 Subordinated Notes permitted under this Agreement so long as
the remaining funds on deposit in such Cash Collateral Account are sufficient to satisfy any remaining scheduled interest payments thereon and to repay the principal, interest and any other cash payment obligations on the Existing 2018 Subordinated
Notes in full at maturity (it being understood that to the extent that the amount of such funds on deposit at any time shall exceed the aggregate amount of the remaining outstanding obligations, such excess amount shall be remitted to the Borrower
at its written request so long as no Default or Event of Default then exists or would result therefrom)). 
 “Scheduled A Term Loan
Repayment” has the meaning specified in Section 2.6(b). 
 “Scheduled A Term Loan Repayment Date” has
the meaning specified in Section 2.6(b). 
 “Scheduled A Term Loan Springing Maturity Date” has the meaning
specified in the definition of “Scheduled A Term Loan Maturity Date”. 
 “Scheduled B Term Loan Maturity Date”
means June 18, 2022; provided, however, in the event that any Existing 2018 Subordinated Notes remain outstanding on April 1, 2018, then the Scheduled B Term Loan Maturity Date instead shall be April 1, 2018 (the
“Scheduled B Term Loan Springing Maturity Date”) (unless either (x) the outstanding obligations under the Existing 2018 Subordinated Notes (including all interest that will accrue thereon until such time as the Existing 2018
Subordinated Notes have been redeemed or repaid in full in accordance with the terms of the Existing 2018 Subordinated Notes Indenture and the Existing 2018 Subordinated Notes Indenture has been terminated) have been defeased or satisfied and
discharged in accordance with the terms of the Existing Notes Documents with respect to the Existing 2018 Subordinated Notes on such date or (y) cash in an aggregate amount equal to all such outstanding obligations has been deposited as
security for the benefit of the Secured Parties in a manner, on terms and conditions, and pursuant to documentation, in each case reasonably satisfactory to the Administrative Agents (which, in any event, shall require that such cash be deposited in
a Cash 

  
 44 

 
Collateral Account (subject to the Collateral Agent’s security interest under the Guaranty and Security Agreement)), which cash can only be accessed by the Borrower for the purpose of paying
any remaining scheduled interest payments thereon as and when the same shall become due and payable and to repay such Existing 2018 Subordinated Notes in full at maturity or in connection with any tender offer for, repurchase of or other
satisfaction or repayment of, the Existing 2018 Subordinated Notes permitted under this Agreement so long as the remaining funds on deposit in such Cash Collateral Account are sufficient to satisfy any remaining scheduled interest payments thereon
and to repay the principal, interest and any other cash payment obligations on the Existing 2018 Subordinated Notes in full at maturity (it being understood that to the extent that the amount of such funds on deposit at any time shall exceed the
aggregate amount of the remaining outstanding obligations, such excess amount shall be remitted to the Borrower at its written request so long as no Default or Event of Default then exists or would result therefrom)). 

“Scheduled B Term Loan Repayment” has the meaning specified in Section 2.6(c). 

“Scheduled B Term Loan Repayment Date” has the meaning specified in Section 2.6(c). 

“Scheduled B Term Loan Springing Maturity Date” has the meaning specified in the definition of “Scheduled B Term Loan
Maturity Date”. 
 “Scheduled Revolving Credit Termination Date” means June 18, 2020; provided,
however, in the event that any Existing 2018 Subordinated Notes remain outstanding on April 1, 2018, then the Scheduled Revolving Credit Termination Date instead shall be April 1, 2018 (the “Scheduled Revolving Credit
Springing Termination Date”) (unless either (x) the outstanding obligations under the Existing 2018 Subordinated Notes (including all interest that will accrue thereon until such time as the Existing 2018 Subordinated Notes have been
redeemed or repaid in full in accordance with the terms of the Existing 2018 Subordinated Notes Indenture and the Existing 2018 Subordinated Notes Indenture has been terminated) have been defeased or satisfied and discharged in accordance with the
terms of the Existing Notes Documents with respect to the Existing 2018 Subordinated Notes on such date or (y) cash in an aggregate amount equal to all such outstanding obligations has been deposited as security for the benefit of the Secured
Parties in a manner, on terms and conditions, and pursuant to documentation, in each case reasonably satisfactory to the Administrative Agents (which, in any event, shall require that such cash be deposited in a Cash Collateral Account (subject to
the Collateral Agent’s security interest under the Guaranty and Security Agreement)), which cash can only be accessed by the Borrower for the purpose of paying any remaining scheduled interest payments thereon as and when the same shall become
due and payable and to repay such Existing 2018 Subordinated Notes in full at maturity or in connection with any tender offer for, repurchase of or other satisfaction or repayment of, the Existing 2018 Subordinated Notes permitted under this
Agreement so long as the remaining funds on deposit in such Cash Collateral Account are sufficient to satisfy any remaining scheduled interest payments thereon and to repay the principal, interest and any other cash payment obligations on the
Existing 2018 Subordinated Notes in full at maturity (it being understood that to the extent that the amount of such funds on deposit at any time shall exceed the aggregate amount of the remaining outstanding obligations, such excess amount shall be
remitted to the Borrower at its written request so long as no Default or Event of Default then exists or would result therefrom)). 

“Scheduled Revolving Credit Springing Termination Date” has the meaning specified in the definition of “Scheduled
Revolving Credit Termination Date”. 

  
 45 

 “SEC” means The United States Securities and Exchange Commission. 

“Secured Hedging Agreement” means any Hedging Agreement that (a) has been entered into with a Secured Hedging
Counterparty, (b) in the case of a Hedging Agreement not entered into with or provided or arranged by either Administrative Agent or an Affiliate of either Administrative Agent, is expressly identified as being a “Secured Hedging
Agreement” hereunder in a joint notice from such Loan Party and such Person delivered to the Collateral Agent reasonably promptly after the execution of such Hedging Agreement and (c) meets the requirements of Section 8.1(f).

 “Secured Hedging Counterparty” means (a) a Person who has entered into a Hedging Agreement which meets the
requirements of Section 8.1(f) with a Loan Party if such Hedging Agreement was provided or arranged by either Administrative Agent or an Affiliate of either Administrative Agent, and any assignee of such Person or (b) a Lender or an
Affiliate of a Lender who has entered into a Hedging Agreement which meets the requirements of Section 8.1(f) with a Loan Party (or a Person who was a Lender or an Affiliate of a Lender at the time of execution and delivery of such
Hedging Agreement). 
 “Secured Parties” means the Lenders, the L/C Issuers, the Administrative Agents, the Collateral
Agent, any Secured Hedging Counterparty, any Secured Treasury Services Creditor, each other Indemnitee and any other holder of any Obligation of any Loan Party. 

“Secured Treasury Services Agreement” means any Treasury Services Agreement that (a) has been entered into with a
Secured Treasury Services Creditor, (b) has been approved in writing by the Borrower as being a “Secured Treasury Services Agreement” hereunder and (c) is expressly identified as being a “Secured Treasury Services
Agreement” hereunder in a joint written notice from the Borrower and such Secured Treasury Services Creditor delivered to the Collateral Agent reasonably promptly after the execution of such Treasury Services Agreement (it being understood
(i) that any such notice may specify the aggregate amount of obligations under the respective Secured Treasury Services Agreement that is entitled to be secured by the Collateral under the Loan Documents and treated as Obligations hereunder and
thereunder and (ii) to the extent that any such notice does not specify such a limit, then, unless otherwise approved in writing by the Borrower, no more than $10,000,000 in the aggregate of all obligations under all Secured Treasury Services
Agreements shall be entitled to be secured on a ratable basis by the Collateral under the Loan Documents and treated as Obligations hereunder and thereunder). 

“Secured Treasury Services Creditor” means a Lender or an Affiliate of a Lender who has entered into a Treasury Services
Agreement with a Loan Party. 
 “Security” means all Stock, Stock Equivalents, voting trust certificates, bonds,
debentures, instruments and other evidence of Indebtedness, whether or not secured, convertible or subordinated, all certificates of interest, share or participation in, all certificates for the acquisition of, and all warrants, options and other
rights to acquire, any Security. 
 “Sell” means, with respect to any property, to sell, convey, transfer, assign, license,
lease or otherwise dispose of, any interest therein or to permit any Person to acquire any such interest, including, in each case, through a Sale and Leaseback Transaction or through a sale, factoring at maturity, collection of or other disposal,
with or without recourse, of any notes or accounts receivable. Conjugated forms thereof and the noun “Sale” have correlative meanings. 

  
 46 

 “Solvent” means, with respect to any Person or any group of Persons taken
together on a consolidated basis as of any date of determination, that, as of such date, (a) the value of the assets of such Person or group (both at fair value and present fair saleable value) is greater than the total amount of liabilities
(including contingent and unliquidated liabilities) of such Person or group, (b) such Person or group is able to pay all liabilities of such Person or group as such liabilities mature and (c) such Person or group does not have unreasonably
small capital. In computing the amount of contingent or unliquidated liabilities at any time, such liabilities shall be computed at the amount that, in light of all the facts and circumstances existing at such time, represents the amount that can
reasonably be expected to become an actual or matured liability. 
 “SPDH Sale” means the Sale of (x) all of the Stock
and Stock Equivalents of, and/or (y) any or all of the assets of, the P&G JV Companies, Inverness Medical, LLC (but only with regard to the assets thereof relating to the business of the P&G JV Companies) and/or Alere (Shanghai)
Diagnostics Co., Ltd. (but only with regard to the assets thereof relating to the business of the P&G JV Companies), and any of their respective Subsidiaries or any direct or indirect holding company thereof (including SPDH, Inc.) holding,
directly or indirectly, the Stock and Stock Equivalents of either of the P&G JV Companies, Inverness Medical, LLC and/or Alere (Shanghai) Diagnostics Co., Ltd., as applicable, and any of their respective Subsidiaries (provided that such
holding company does not engage in any material business or own any material assets other than owning, directly or indirectly, the Stock and Stock Equivalents of either of the P&G JV Companies, Inverness Medical, LLC and/or Alere (Shanghai)
Diagnostics Co., Ltd., as applicable, and any of their respective Subsidiaries). 
 “Specified Refinancing Revolving Credit
Commitments” has the meaning specified in Section 2.22(a). 
 “Specified Refinancing Revolving Credit
Facility” means the Specified Refinancing Revolving Credit Commitments and the provisions herein related to the Revolving Loans, any Swing Loans or Letters of Credit incurred under the Specified Refinancing Revolving Credit Commitments.

 “Specified Refinancing Term Loan Commitment” has the meaning specified in the definition of “Term Loan
Commitment”. 
 “Specified Refinancing Term Loan Facility” means the Specified Refinancing Term Loans and the
provisions herein related to the Specified Refinancing Term Loans. 
 “Specified Refinancing Term Loans” has the meaning
specified in Section 2.22(a). 
 “SPV” means any special purpose funding vehicle identified as such in a
writing by any Lender to the Applicable Administrative Agent. 
 “Stock” means all shares of capital stock (whether
denominated as common stock or preferred stock), equity interests, beneficial, partnership or membership interests, joint venture interests, participations or other ownership or profit interests in or equivalents (regardless of how designated) of or
in a Person (other than an individual), whether voting or non-voting. 
 “Stock Equivalents” means all securities
convertible into or exchangeable for Stock or any other Stock Equivalent and all warrants, options or other rights to purchase, subscribe for or otherwise acquire any Stock or any other Stock Equivalent, whether or not presently convertible,
exchangeable or exercisable. 

  
 47 

 “Subordinated Debt” means any Indebtedness that is subordinated to the payment
in full of the Obligations on terms and conditions reasonably satisfactory to the Administrative Agents (including the Existing Subordinated Notes, the New 2023 Subordinated Notes and any Permitted Additional Debt, Permitted Acquisition Debt or
other Junior Indebtedness that satisfies the criteria for subordination set forth in this definition). 
 “Subsidiary”
means, with respect to any Person, any corporation, partnership, joint venture, limited liability company, association or other entity, the management of which is, directly or indirectly, controlled by, or of which an aggregate of more than 50% of
the outstanding Voting Stock is, at the time, owned or controlled directly or indirectly by, such Person or one or more Subsidiaries of such Person. Based on the capital structure and ownership of the P&G JV Companies as of the Closing Date, the
P&G JV Companies are not Subsidiaries of any Group Member. Notwithstanding the foregoing or anything else in this Agreement or any other Loan Document to the contrary, other than for purposes of (x) the definition of “Unrestricted
Subsidiary” contained herein and (y) Sections 4.1(e) (to the extent relating to Anti-Corruption Laws, Anti-Terrorism Laws, Anti-Money Laundering Laws and Sanctions Laws and Regulations), 4.21 and 7.2 (to the extent
relating to Anti-Corruption Laws, Anti-Terrorism Laws, Anti-Money Laundering Laws and Sanctions Laws and Regulations), an Unrestricted Subsidiary (and its Subsidiaries) shall be deemed not to be a Subsidiary of the Borrower or any of its other
Subsidiaries for purposes of this Agreement or any other Loan Document. 
 “Substitute Lender” has the meaning specified in
Section 2.18(a). 
 “Swap Obligation” means, with respect to any Guarantor, any obligation to pay or perform
under any Secured Hedging Agreement that constitutes a “swap” within the meaning of section 1a(47) of the Commodity Exchange Act. 

“SWDA” means the Solid Waste Disposal Act (42 U.S.C. §§ 6901 et seq.). 

“Swingline Commitment” means $25,000,000. 

“Swingline Lender” means, each in its capacity as Swingline Lender hereunder, GE Capital or, upon the resignation of GE
Capital as Pro Rata Administrative Agent hereunder, any Lender (or Affiliate or Approved Fund of any Lender) that agrees, with the approval of the Pro Rata Administrative Agent (or, if there is no such successor Pro Rata Administrative Agent, the
Required Lenders) and the Borrower, to act as the Swingline Lender hereunder. 
 “Swingline Request” has the meaning
specified in Section 2.3(b). 
 “Swing Loan” has the meaning specified in Section 2.3(a). 

“Swing Loan Exposure” means, at any time, the aggregate principal amount of all Swing Loans outstanding at such time. The
Swing Loan Exposure of any Revolving Credit Lender at any time shall be its Revolving Credit Percentage of the aggregate Swing Loan Exposure at such time. 

  
 48 

 “Swissco” means Alere Switzerland GmbH, an entity organized under the laws of
Switzerland. 
 “Swiss Pledge Agreement” has the meaning specified in Section 3.1(a)(iii). 

“Tax Affiliate” means (a) the Borrower and its Subsidiaries and (b) any Affiliate of the Borrower with which the
Borrower files or is eligible to file consolidated, combined or unitary tax returns. 
 “Tax Return” has the meaning
specified in Section 4.8. 
 “Taxes” has the meaning specified in Section 2.17(a). 

“TechLab Sale” means the sale of all of the Borrower’s or any of its Subsidiaries’ Investment in TechLab, Inc.,
which may include any assets directly associated with the business thereof and held by the Borrower or any of its Subsidiaries. 

“Term Loan” means each Initial Term Loan, and, unless the context shall otherwise require, each Incremental Term Loan, each
Extended Term Loan and each Specified Refinancing Term Loan. 
 “Term Loan Commitment” means, with respect to each Term
Loan Lender, the A Term Loan Commitment, the B Term Loan Commitment and any Incremental Term Loan Commitment of such Lender, as amended to reflect Assignments and as such amount may be reduced pursuant to this Agreement. In addition, the Term Loan
Commitment of each Lender shall include any commitment to make Extended Term Loans (the “Extended Term Loan Commitment”) or any commitment to make Specified Refinancing Term Loans (the “Specified Refinancing Term Loan
Commitment”). 
 “Term Loan Facility” means, in respect of each Tranche of Term Loans, the Term Loan Commitments,
the related Term Loans and the provisions herein related to such Tranche of Term Loans. 
 “Term Loan Lender” means each
Lender that has a Term Loan Commitment or that holds a Term Loan. 
 “Term Loan Percentage” of a Tranche of Term Loans
means, at any time, a fraction (expressed as a percentage), the numerator of which is equal to the aggregate outstanding principal amount of all Term Loans of such Tranche at such time and the denominator of which is equal to the aggregate
outstanding principal amount of all Term Loans of all Tranches at such time. 
 “Title IV Plan” means a Pension Plan
subject to Title IV of ERISA, other than a Multiemployer Plan, to which any ERISA Affiliate maintains, sponsors or contributes to or has maintained, sponsored or contributed to within the last 6 years or otherwise has any obligation or liability,
contingent or otherwise. 
 “Total Assets” means the total assets of the Borrower and its Subsidiaries on a
consolidated basis, as shown on the most recent balance sheet of the Borrower referred to in Section 4.4(a) or delivered pursuant to Section 6.1(a) or (b) (but excluding, for this purpose, the value of the Stock
of any Unrestricted Subsidiaries). 

  
 49 

 “Total A Term Loan Commitment” means, at any time, the sum of the A Term Loan
Commitments of each of the Lenders at such time. 
 “Total B Term Loan Commitment” means, at any time, the sum of the B
Term Loan Commitments of each of the Lenders at such time. 
 “Total Commitment” means, at any time, the sum of the
Commitments of each of the Lenders at such time. 
 “Total Revolving Credit Commitments” means, at any time, the sum of the
Revolving Credit Commitments of each of the Lenders at such time. 
 “Trademarks” means all right, title and interest (and
all related IP Ancillary Rights) arising under any Requirement of Law in or relating to trademarks, trade names, corporate names, company names, business names, fictitious business names, trade styles, service marks, logos and other source or
business identifiers and, in each case, all goodwill associated therewith, all registrations thereof and all applications therefor. 

“Trade Secrets” means all right, title and interest (and all related IP Ancillary Rights) arising under any Requirement of
Law in or relating to trade secrets. 
 “Tranche” means the respective facility and commitments utilized in making Loans
hereunder, with there being four separate Tranches as of the Closing Date, i.e., A Term Loans, B Term Loans, Revolving Loans and Swing Loans; provided that, for the purposes of Sections 2.6(a), 2.19, 2.22,
2.23, 11.1 and 11.2(b), Revolving Loans and Swing Loans shall be deemed to constitute part of a single “Tranche”. In addition, notwithstanding the foregoing, any Incremental Term Loans incurred after the Closing Date
shall, unless added to the B Term Loans or any then outstanding Incremental Term Loans, be made pursuant to one or more additional Tranches of Term Loans which shall be designated in accordance with the relevant requirements specified in
Section 2.19. 
 “Transactions” means, collectively, (i) the consummation of the Refinancing,
(ii) the entering into of the Loan Documents, the incurrence of Loans on the Closing Date and the use of proceeds thereof and (iii) the payment of all fees and expenses in connection with the foregoing. 

“Treasury Services” means treasury, depositary, automated clearinghouse transfers of funds, credit cards, purchasing cards
and other cash management services (including, without limitation, overnight overdraft services, lockbox services, wire transfer services and electronic funds transfer services). 

“Treasury Services Agreements” means any written agreements and/or arrangements to provide Treasury Services. 

“Type” means the type or Loan determined with regard to the interest option applicable thereto, i.e., whether a Base
Rate Loan or a Eurodollar Rate Loan. 

  
 50 

 “UCC” means the Uniform Commercial Code of any applicable jurisdiction and, if
the applicable jurisdiction shall not have any Uniform Commercial Code, the Uniform Commercial Code as in effect in the State of New York. 

“Unfunded Pension Liability” means, at any time, the aggregate amount, if any, of the sum of (a) the amount by which the
present value of all accrued benefits under each Title IV Plan exceeds the fair market value of all assets of such Title IV Plan allocable to such benefits in accordance with Title IV of ERISA, all determined as of the most recent valuation date for
each such Title IV Plan using the actuarial assumptions for funding purposes in effect under such Title IV Plan, and (b) for a period of 5 years following a transaction which might reasonably be expected to be covered by Section 4069 of
ERISA, the liabilities (whether or not accrued, but only to the extent such liabilities could reasonably be expected to have a Material Adverse Effect) that could be avoided by any Group Member or any ERISA Affiliate as a result of such transaction.

 “United States” or “U.S.” means the United States of America. 

“Unrestricted” means, when referring to cash or Cash Equivalents of any Loan Party, that such cash or Cash Equivalents are
not Restricted. 
 “Unrestricted Subsidiary” means (a) any Subsidiary of the Borrower that is designated as an
Unrestricted Subsidiary pursuant to Section 7.15, until such Person ceases to be an Unrestricted Subsidiary of the Borrower in accordance with Section 7.15 and (b) any Subsidiary of any Unrestricted Subsidiary designated
pursuant to preceding clause (a) (and which has not so ceased to be an Unrestricted Subsidiary). 
 “Unused Revolver Commitment
Fee” has the meaning specified in Section 2.11. 
 “U.S. Lender Party” means each of each
Administrative Agent, each Lender, each L/C Issuer, each SPV and each participant, in each case that is a Domestic Person. 

“Voting Stock” means Stock of any Person having ordinary power to vote in the election of members of the board of directors,
managers, trustees or other controlling Persons of such Person (irrespective of whether, at the time, Stock of any other class or classes of such entity shall have or might have voting power by reason of the occurrence of any contingency). 

“Wampole Business” means the business conducted by various Subsidiaries of the Borrower relating to the design, manufacture
and sale of laboratory diagnostics and associated products related to the diagnosis of certain diseases and medical conditions. 

“Wampole Sale” means the Sale of any or all of the assets of the Wampole Business or the Stock or Stock Equivalents of any
Subsidiary that conducts the Wampole Business or any direct or indirect holding company thereof holding, directly or indirectly, the Stock and Stock Equivalents of any such Subsidiary (provided that such Subsidiary or holding company does not
engage in any material business or own any material assets other than the Wampole Business or owning, directly or indirectly, the Stock and Stock Equivalents of any such Subsidiary). 

“Weighted Average Life to Maturity” means, when applied to any Indebtedness at any date, the number of years obtained by
dividing: (i) the sum of the products obtained by multiplying (a) the amount of each then remaining installment, sinking fund, serial maturity or 

  
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other required payments of principal, including payment at final maturity, in respect thereof, by (b) the number of years (calculated to the nearest one-twelfth) that will elapse between
such date and the making of such payment; by (ii) the then outstanding principal amount of such Indebtedness. 
 “Wholly Owned
Subsidiary” of any Person means any Subsidiary of such Person, all of the Stock of which (other than nominal holdings and director’s qualifying shares) is owned by such Person, either directly or through one or more Wholly Owned
Subsidiaries of such Person. 
 “Working Capital” means, for any Person at any date, its Consolidated Current Assets at
such date minus its Consolidated Current Liabilities at such date. 
 Section 1.2 UCC Terms. The following terms
have the meanings given to them in the applicable UCC: “commodity account”, “commodity contract”, “commodity intermediary”, “deposit account”, “entitlement holder”, “entitlement order”,
“equipment”, “financial asset”, “general intangible”, “goods”, “instruments”, “inventory”, “securities account”, “securities intermediary” and “security
entitlement”. 
 Section 1.3 Accounting Terms and Principles. 

(a) GAAP. All accounting determinations required to be made pursuant hereto shall, unless expressly otherwise provided herein, be made
in accordance with GAAP. No change in the accounting principles used in the preparation of any Financial Statement hereafter adopted by the Borrower shall be given effect if such change would affect a calculation that measures compliance with any
provision of Article V or VIII unless the Borrower, the Administrative Agents and the Required Lenders agree to modify such provisions to reflect such changes in GAAP and, unless such provisions are modified, all Financial
Statements, Compliance Certificates and similar documents provided hereunder shall be provided together with a reconciliation between the calculations and amounts set forth therein before and after giving effect to such change in GAAP. For the
avoidance of doubt, all operating lease expense with respect to leases of the Borrower and its Subsidiaries that would constitute operating leases under GAAP as in effect on the Closing Date shall not be included in the calculations of Capital
Leases and Capital Lease Obligations hereunder unless the Borrower, the Administrative Agents and the Required Lenders otherwise agree to modify the provisions hereof in accordance with the immediately preceding sentence. In addition, to the extent
that (x) the obligations in respect of any issue of Existing Notes, any Permitted Additional Debt or any Permitted Refinancing of any of the foregoing (including all interest that will accrue thereon through the relevant redemption or maturity
date) and the relevant indenture governing such Indebtedness are defeased or satisfied and discharged in accordance with the terms of such indenture or (y) in the case of any Existing 2016 Subordinated Convertible Notes or Existing 2018
Subordinated Notes, cash is deposited with the Collateral Agent as security for the benefit of the Secured Parties in an amount sufficient to repay in full such Indebtedness at maturity pursuant to arrangements reasonably satisfactory to the
Administrative Agents, then, in any case, such Indebtedness will not be considered outstanding for purposes of this Agreement (including any of the covenants or other provisions in Articles V or VIII). Unless otherwise expressly
provided for herein, the term “consolidated” (including “Consolidated”) with respect to any Person refers to such Person consolidated with its Subsidiaries, and excludes from such consolidation any Unrestricted Subsidiary as if
such Unrestricted Subsidiary were not an Affiliate of such Person (and, without limiting the foregoing, it is understood and agreed that, for purposes of calculating the Applicable Margin and all financial ratios and financial terms contained herein
or in any other Loan Document, the financial results of all Unrestricted Subsidiaries shall be ignored). 

  
 52 

 (b) Pro Forma. All components of financial calculations made to determine compliance with
Article V shall be adjusted on a Pro Forma Basis to include or exclude, as the case may be, without duplication, such components of such calculations attributable to any Pro Forma Transaction consummated after the first day of the
applicable period of determination and prior to the end of such period, as determined in good faith by the Borrower based on assumptions expressed therein and that were reasonable based on the information available to the Borrower at the time of
preparation of the Compliance Certificate setting forth such calculations. 
 Section 1.4 Payments. The Administrative
Agents may set up standards and procedures to determine or redetermine the equivalent in Dollars of any amount expressed in any currency other than Dollars and otherwise may, but shall not be obligated to, rely on any determination made by any Loan
Party or any L/C Issuer. Any such determination or redetermination by the Administrative Agents shall be conclusive and binding for all purposes, absent manifest error. No determination or redetermination by any Secured Party or Loan Party and no
other currency conversion shall change or release any obligation of any Loan Party or of any Secured Party (other than either Administrative Agent and its Related Persons) under any Loan Document, each of which agrees to pay separately for any
shortfall remaining after any conversion and payment of the amount as converted. The Administrative Agents may round up or down, and may set up appropriate mechanisms to round up or down, any amount hereunder to nearest higher or lower amounts and
may determine reasonable de minimis payment thresholds. 
 Section 1.5 Interpretation. 

(a) Certain Terms. Except as set forth in any Loan Document, all accounting terms not specifically defined herein shall be construed in
accordance with GAAP (except for the term “property”, which shall be interpreted as broadly as possible, including, in any case, cash, Securities, other assets, rights under Contractual Obligations and Permits and any right or
interest in any property). The terms “herein”, “hereof” and similar terms refer to this Agreement as a whole. In the computation of periods of time from a specified date to a later specified date in any Loan
Document, the terms “from” means “from and including” and the words “to” and “until” each mean “to but excluding” and the word “through” means “to and
including.” In any other case, the term “including” when used in any Loan Document means “including without limitation.” The term “documents” means all writings, however evidenced and whether in
physical or electronic form, including all documents, instruments, agreements, notices, demands, certificates, forms, financial statements, opinions and reports. The term “incur” means incur, create, make, issue, assume or otherwise
become directly or indirectly liable in respect of or responsible for, in each case whether directly or indirectly, and the terms “incurrence” and “incurred” and similar derivatives shall have correlative meanings. 

(b) Certain References. Unless otherwise expressly indicated, references (i) in this Agreement to an Exhibit, Schedule, Article,
Section or clause refer to the appropriate Exhibit or Schedule to, or Article, Section or clause in, this Agreement and (ii) in any Loan Document, to (A) any agreement shall include, without limitation, all exhibits, schedules, appendixes
and annexes to such agreement and, unless any prior consent of any Secured Party or the Loan Parties expressly required hereunder is not obtained, any modification, amendment, restatement or amendment and restatement to any term of such agreement,
(B) any statute shall be to such statute as modified from time to time and to any successor legislation thereto, in each case 

  
 53 

 
as in effect at the time any such reference is operative and (C) any time of day shall be a reference to New York time. Titles of articles, sections, clauses, exhibits, schedules and annexes
contained in any Loan Document are without substantive meaning or content of any kind whatsoever and are not a part of the agreement between the parties hereto. Unless otherwise expressly indicated, the meaning of any term defined (including by
reference) in any Loan Document shall be equally applicable to both the singular and plural forms of such term. 
 Section 1.6
Available Amount Transactions. If more than one action occurs on any given date the permissibility of the taking of which is determined hereunder by reference to the amount of the Available Amount immediately prior to the taking of such
action, the permissibility of the taking of each such action shall be determined independently and in no event may any two or more such actions be treated as occurring simultaneously. 

ARTICLE II 
 THE FACILITIES 

Section 2.1 The Commitments. 

(a) Revolving Credit Commitments. On the terms and subject to the conditions contained in this Agreement, each Revolving Credit
Lender severally, but not jointly, agrees to make loans in Dollars (each a “Revolving Loan”) to the Borrower from time to time on any Business Day during the period from the date hereof until the Revolving Credit Termination Date in
an aggregate principal amount at any time outstanding for all such loans by such Lender not to exceed such Lender’s Revolving Credit Commitment; provided, however, that at no time shall any Revolving Credit Lender be obligated to
make a Revolving Loan in excess of such Lender’s Pro Rata Share of the amount by which the then effective Revolving Credit Commitments exceeds the aggregate Revolving Credit Outstandings at such time. Within the limits set forth in the first
sentence of this clause (a), amounts of Revolving Loans repaid may be reborrowed under this Section 2.1. 
 (b) Term
Loan Commitments . (i) On the terms and subject to the conditions contained in this Agreement, each Term Loan Lender severally, but not jointly, agrees to make a loan (each an “A Term Loan”) in Dollars to the Borrower on
the Closing Date in an amount not to exceed such Lender’s A Term Loan Commitment. Amounts of A Term Loans repaid may not be reborrowed. 

(ii) On the terms and subject to the conditions contained in this Agreement, each Term Loan Lender severally, but not jointly,
agrees to make a loan (each a “B Term Loan”) in Dollars to the Borrower on the Closing Date in an amount not to exceed such Lender’s B Term Loan Commitment. Amounts of B Term Loans repaid may not be reborrowed. 

Section 2.2 Borrowing Procedures. 

(a) Notice From the Borrower. Each Borrowing shall be made on notice given by the Borrower to the Applicable Administrative Agent not
later than (i) 10:00 a.m. on the date of, in the case of a Borrowing of Base Rate Loans, and (ii) 11:00 a.m. on the third Business Day prior to the date of, in the case of a Borrowing of Eurodollar Rate Loans, the proposed Borrowing.
Each such notice may be made in a writing substantially in the form of Exhibit C (a “Notice of Borrowing”) duly completed or by telephone if confirmed promptly, but in any event

  
 54 

 
within one Business Day and prior to such Borrowing, with such a Notice of Borrowing. Loans shall be made as Base Rate Loans unless, outside of a suspension period pursuant to
Section 2.15, the Notice of Borrowing specifies that all or a portion thereof shall be Eurodollar Rate Loans. The Notice of Borrowing shall specify whether the loans being incurred pursuant to such Borrowing shall constitute Initial Term
Loans or Revolving Loans. Each Borrowing shall be in an aggregate amount that is an integral multiple of $1,000,000. 
 (b) Notice to
Each Lender. The Applicable Administrative Agent shall give to each relevant Lender prompt notice of the Applicable Administrative Agent’s receipt of a Notice of Borrowing and, if Eurodollar Rate Loans are properly requested in such Notice
of Borrowing, prompt notice of the applicable interest rate. Each Lender shall, before 12:00 noon on the date of the proposed Borrowing, make available to the Applicable Administrative Agent at its address referred to in
Section 11.11, such Lender’s Pro Rata Share of such proposed Borrowing. Upon fulfillment or due waiver (i) on the Closing Date, of the applicable conditions set forth in Section 3.1 and (ii) on the Closing Date
and on the date of each borrowing of Loans thereafter, of the applicable conditions set forth in Section 3.2, the Applicable Administrative Agent shall make the funds made available to it by the Lenders before 12:00 noon on the date of
the proposed Borrowing available to the Borrower. 
 (c) Non-Funding Lenders. Unless the Applicable Administrative Agent shall have
received notice from any Lender prior to the date such Lender is required to make any payment hereunder with respect to any Loan or any participation in any Swing Loan or Letter of Credit that such Lender will not make such payment (or any portion
thereof) available to the Applicable Administrative Agent, the Applicable Administrative Agent may assume that such Lender has made such payment available to the Applicable Administrative Agent on the date such payment is required to be made in
accordance with this Article II and the Applicable Administrative Agent may, in reliance upon such assumption, make available to the Borrower on such date a corresponding amount. The Borrower agrees to repay to the Applicable
Administrative Agent on demand such amount (until repaid by such Lender) with interest thereon for each day from the date such amount is made available to the Borrower until the date such amount is repaid to the Applicable Administrative Agent, at
the interest rate applicable to the Obligation that would have been created when the Applicable Administrative Agent made available such amount to the Borrower had such Lender made a corresponding payment available; provided, however,
that such payment shall not relieve such Lender of any obligation it may have to the Borrower, the Swingline Lender or any L/C Issuer. In addition, any Lender that shall not have made available to the Applicable Administrative Agent any portion of
any payment described above (any such Lender, a “Non-Funding Lender”) agrees to pay such amount to the Applicable Administrative Agent on demand together with interest thereon, for each day from the date such amount is made
available to the Borrower until the date such amount is repaid to the Applicable Administrative Agent, at the Federal Funds Rate for the first Business Day and thereafter (i) in the case of a payment in respect of a Loan, at the interest rate
applicable at the time to such Loan and (ii) otherwise, at the interest rate applicable to Base Rate Loans under the Revolving Credit Facility. Such repayment shall then constitute the funding of the corresponding Loan (including any Loan
deemed to have been made hereunder with such payment) or participation. The existence of any Non-Funding Lender shall not relieve any other Lender of its obligations under any Loan Document, but no other Lender shall be responsible for the failure
of any Non-Funding Lender to make any payment required under any Loan Document. 

  
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 Section 2.3 Swing Loans. 

(a) Availability. On the terms and subject to the conditions contained in this Agreement, the Swingline Lender may, in its sole
discretion, make loans in Dollars (each a “Swing Loan”) available to the Borrower under the Revolving Credit Facility from time to time on any Business Day during the period from the date hereof until the Revolving Credit
Termination Date in an aggregate principal amount at any time outstanding not to exceed its Swingline Commitment; provided, however, that the Swingline Lender may not make any Swing Loan (x) to the extent that after giving effect
to such Swing Loan, the aggregate Revolving Credit Outstandings would exceed the Revolving Credit Commitments and (y) in the period commencing on the first Business Day after it receives notice from the Pro Rata Administrative Agent or the
Required Revolving Credit Lenders that one or more of the conditions precedent contained in Section 3.2 are not satisfied and ending when such conditions are satisfied or duly waived. In connection with the making of any Swing Loan, the
Swingline Lender may but shall not be required to determine that, or take notice whether, the conditions precedent set forth in Section 3.2 have been satisfied or waived. Each Swing Loan shall be a Base Rate Loan and must be repaid in
full on the earliest of (i) the funding date of any Borrowing of Revolving Loans and (ii) the Revolving Credit Termination Date. Within the limits set forth in the first sentence of this clause (a), amounts of Swing Loans repaid may
be reborrowed under this clause (a). 
 (b) Borrowing Procedures. In order to request a Swing Loan, the Borrower shall give to
the Applicable Administrative Agent a notice to be received not later than 1:00 p.m. on the day of the proposed borrowing, which may be made in a writing substantially in the form of Exhibit D duly completed (a “Swingline
Request”) or by telephone if confirmed promptly but, in any event, prior to such borrowing, with such a Swingline Request. In addition, if any Notice of Borrowing requests a Borrowing of Base Rate Loans, the Swing Line Lender may,
notwithstanding anything else to the contrary in Section 2.2, make a Swing Loan available to the Borrower in an aggregate amount not to exceed such proposed Borrowing, and the aggregate amount of the corresponding proposed Borrowing
shall be reduced accordingly by the principal amount of such Swing Loan. The Applicable Administrative Agent shall promptly notify the Swingline Lender of the details of the requested Swing Loan. Upon receipt of such notice and subject to the terms
of this Agreement, the Swingline Lender may make a Swing Loan available to the Borrower by making the proceeds thereof available to the Applicable Administrative Agent and, in turn, the Applicable Administrative Agent shall make such proceeds
available to the Borrower on the date set forth in the relevant Swingline Request. 
 (c) Refinancing Swing Loans. The Swingline
Lender may at any time forward a demand to the Applicable Administrative Agent (which the Applicable Administrative Agent shall, upon receipt, forward to each Revolving Credit Lender) that each Revolving Credit Lender pay to the Applicable
Administrative Agent, for the account of the Swingline Lender, such Revolving Credit Lender’s Pro Rata Share of all or a portion of the outstanding Swing Loans. Each Revolving Credit Lender shall pay such Pro Rata Share to the Applicable
Administrative Agent for the account of the Swingline Lender. Upon receipt by the Applicable Administrative Agent of such payment (other than during the continuation of any Event of Default under Section 9.1(e)), such Revolving Credit Lender
shall be deemed to have made a Revolving Loan to the Borrower, which, upon receipt of such payment by the Swingline Lender from the Applicable Administrative Agent, the Borrower shall be deemed to have used in whole to refinance such Swing Loan. In
addition, regardless of whether any such demand is made, upon the occurrence of any Event of Default under Section 9.1(e), each Revolving Credit Lender shall be deemed to have acquired, without recourse or warranty, an undivided interest and
participation in each Swing Loan in an amount equal to such Lender’s Pro Rata Share of such Swing Loan. If 

  
 56 

 
any payment made by any Revolving Credit Lender as a result of any such demand is not deemed a Revolving Loan, such payment shall be deemed a funding by such Lender of such participation. Such
participation shall not be otherwise required to be funded. Upon receipt by the Swingline Lender of any payment from any Revolving Credit Lender pursuant to this clause (c) with respect to any portion of any Swing Loan, the Swingline
Lender shall promptly pay over to such Revolving Credit Lender all payments of principal (to the extent received after such payment by such Lender) and interest (to the extent accrued with respect to periods after such payment) received by the
Swingline Lender with respect to such portion. 
 (d) Obligation to Fund Absolute. Each Revolving Credit Lender’s obligations
pursuant to clause (c) above shall be absolute, unconditional and irrevocable and shall be performed strictly in accordance with the terms of this Agreement under any and all circumstances whatsoever, including (A) the existence of
any setoff, claim, abatement, recoupment, defense or other right that such Lender, any Affiliate thereof or any other Person may have against the Swing Loan Lender, any other Secured Party or any other Person, (B) the failure of any condition
precedent set forth in Section 3.2 to be satisfied or the failure of the Borrower to deliver any notice set forth in Section 2.2(a) (each of which requirements the Revolving Credit Lenders hereby irrevocably waive) and
(C) any adverse change in the condition (financial or otherwise) of any Loan Party. 
 Section 2.4 Letters of
Credit. 
 (a) Commitment and Conditions. (A) On the terms and subject to the conditions contained herein, each L/C Issuer
agrees to Issue, at the request of the Borrower, in accordance with such L/C Issuer’s usual and customary business practices, and for the account of the Borrower (or, as long as the Borrower remains responsible for the payment in full of all
amounts drawn thereunder and related fees, costs and expenses, for the account of any Group Member), Letters of Credit (denominated in Dollars in a minimum face amount of $1,000,000 for each Letter of Credit (or such lesser face amount as may be
acceptable to the respective L/C Issuer)) from time to time on any Business Day during the period from the Closing Date through the earlier of the Revolving Credit Termination Date and 5 days prior to the Scheduled Revolving Credit Termination Date;
provided, however, that such L/C Issuer shall not be under any obligation to Issue any Letter of Credit upon the occurrence of any of the following, after giving effect to such Issuance: 

(i) (A) the aggregate Revolving Credit Outstandings would exceed the aggregate Revolving Credit Commitments or (B) the L/C
Obligations for all Letters of Credit would exceed the L/C Sublimit; 
 (ii) the expiration date of such Letter of Credit
(A) is not a Business Day, (B) is more than one year after the date of issuance thereof or (C) is later than 5 days prior to the Scheduled Revolving Credit Termination Date; provided, however, that any Letter of
Credit with a term not exceeding one year may provide for its renewal for additional one year periods as long as (x) each of the Borrower and such L/C Issuer have the option to prevent such renewal before the expiration of such term or any such
additional one year period and (y) neither such L/C Issuer nor the Borrower shall permit any such renewal to extend such expiration date beyond the date set forth in clause (C) above; or 

  
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 (iii) (A) any fee due in connection with, and on or prior to, such Issuance has
not been paid, (B) such Letter of Credit is requested to be Issued in a form that is not acceptable to such L/C Issuer or (C) such L/C Issuer shall not have received, each in form and substance reasonably acceptable to it and duly executed
by the Borrower (and, if such Letter of Credit is issued for the account of any other Group Member, such Group Member), the documents that such L/C Issuer generally uses in the ordinary course of its business for the Issuance of letters of credit of
the type of such Letter of Credit (collectively, the “L/C Reimbursement Agreement”). 
 For each such Issuance, the applicable L/C
Issuer may, but shall not be required to, determine that, or take notice whether, the conditions precedent set forth in Section 3.2 have been satisfied or waived in connection with the Issuance of any Letter of Credit; provided,
however, that no Letter of Credit shall be Issued during the period starting on the first Business Day after the receipt by such L/C Issuer of notice from the Pro Rata Administrative Agent or the Required Revolving Credit Lenders that any
condition precedent contained in Section 3.2 is not satisfied and ending on the date all such conditions are satisfied or duly waived. 

(B) Schedule 2.4 contains a description of letters of credit that were issued pursuant to the Existing Credit Agreement
and which remain outstanding on the Closing Date (and setting forth, with respect to each such letter of credit, (i) the name of the issuing lender, (ii) the letter of credit number, (iii) the name(s) of the account party or account
parties, (iv) the stated amount, (v) the currency in which the letter of credit is denominated, (vi) the name of the beneficiary, (vii) the expiry date and (viii) whether such letter of credit constitutes a standby letter of
credit or a commercial letter of credit). Each such letter of credit, including any extension or renewal thereof in accordance with the terms thereof and hereof (each, as amended from time to time in accordance with the terms thereof and
hereof, an “Existing Letter of Credit”) shall constitute a “Letter of Credit” for all purposes of this Agreement and shall be deemed issued on the Closing Date. 

(b) Notice of Issuance. The Borrower shall give the relevant L/C Issuer and the Applicable Administrative Agent a notice of any
requested Issuance of any Letter of Credit (other than in respect of an Existing Letter of Credit), which shall be effective only if received by such L/C Issuer and the Applicable Administrative Agent not later than 11:00 a.m. on the third
Business Day prior to the date of such requested Issuance. Such notice may be made in a writing substantially the form of Exhibit E duly completed or in a writing in any other form acceptable to such L/C Issuer (an “L/C
Request”) or by telephone if confirmed promptly, but in any event within one Business Day and prior to such Issuance, with such an L/C Request. 

(c) Reporting Obligations of L/C Issuers. Each L/C Issuer agrees to provide the Applicable Administrative Agent (which, after receipt,
the Applicable Administrative Agent shall provide to each Revolving Credit Lender), in form and substance satisfactory to the Applicable Administrative Agent, each of the following on the following dates: (i) on or prior to (A) any
Issuance of any Letter of Credit by such L/C Issuer, (B) any drawing under any such Letter of Credit or (C) any payment (or failure to pay when due) by the Borrower of any related L/C Reimbursement Obligation, notice thereof, which shall
contain a reasonably detailed description of such Issuance, drawing or payment, (ii) upon the request of the Applicable Administrative Agent (or any Revolving Credit Lender through the Applicable Administrative Agent), copies of any Letter of
Credit Issued by such L/C Issuer and any related L/C Reimbursement Agreement and such other documents and information as may reasonably be 

  
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requested by the Applicable Administrative Agent and (iii) on the first Business Day of each calendar week, a schedule of the Letters of Credit Issued by such L/C Issuer, in form and
substance reasonably satisfactory to the Applicable Administrative Agent, setting forth the L/C Obligations for such Letters of Credit outstanding on the last Business Day of the previous calendar week. 

(d) Acquisition of Participations. Upon any Issuance of a Letter of Credit in accordance with the terms of this Agreement resulting in
any increase in the L/C Obligations, each Revolving Credit Lender shall be deemed to have acquired, without recourse or warranty, an undivided interest and participation in such Letter of Credit and the related L/C Obligations in an amount equal to
such Lender’s Pro Rata Share of such L/C Obligations. 
 (e) Reimbursement Obligations of the Borrower. The Borrower agrees to
pay to the L/C Issuer of any Letter of Credit each L/C Reimbursement Obligation owing with respect to such Letter of Credit no later than the first Business Day after the Borrower receives notice from such L/C Issuer that payment has been made under
such Letter of Credit or that such L/C Reimbursement Obligation is otherwise due (the “L/C Reimbursement Date”) with interest thereon computed as set forth in clause (i) below. In the event that any L/C Issuer incurs any
L/C Reimbursement Obligation not repaid by the Borrower as provided in this clause (e) (or any such payment by the Borrower is rescinded or set aside for any reason), such L/C Issuer shall promptly notify the Applicable
Administrative Agent of such failure (and, upon receipt of such notice, the Applicable Administrative Agent shall forward a copy to each Revolving Credit Lender) and, irrespective of whether such notice is given, such L/C Reimbursement Obligation
shall be payable on demand by the Borrower with interest thereon computed (i) from the date on which such L/C Reimbursement Obligation arose to the L/C Reimbursement Date, at the interest rate applicable during such period to Revolving Loans
that are Base Rate Loans and (ii) thereafter until payment in full, at the interest rate applicable during such period to past due Revolving Loans that are Base Rate Loans. 

(f) Reimbursement Obligations of the Revolving Credit Lenders. Upon receipt of the notice described in clause (e) above
from the Applicable Administrative Agent, each Revolving Credit Lender shall pay to the Applicable Administrative Agent for the account of such L/C Issuer its Pro Rata Share of such L/C Reimbursement Obligation. By making such payment (other than
during the continuation of an Event of Default under Section 9.1(e)), such Lender shall be deemed to have made a Revolving Loan to the Borrower, which, upon receipt thereof by such L/C Issuer, the Borrower shall be deemed to have used in
whole to repay such L/C Reimbursement Obligation. Any such payment that is not deemed a Revolving Loan shall be deemed a funding by such Lender of its participation in the applicable Letter of Credit and the related L/C Obligations. Such
participation shall not otherwise be required to be funded. Upon receipt by any L/C Issuer of any payment from any Lender pursuant to this clause (f) with respect to any portion of any L/C Reimbursement Obligation, such L/C Issuer shall
promptly pay over to such Lender all payments received after such payment by such L/C Issuer with respect to such portion. 
 (g)
Obligations Absolute. The obligations of the Borrower and the Revolving Credit Lenders pursuant to clauses (d), (e) and (f) above shall be absolute, unconditional and irrevocable and performed strictly in
accordance with the terms of this Agreement irrespective of (i) (A) the invalidity or unenforceability of any term or provision in any Letter of Credit, any document transferring or purporting to transfer a Letter of Credit, any Loan
Document (including the sufficiency of any such instrument), or any modification to any 

  
 59 

 
provision of any of the foregoing, (B) any document presented under a Letter of Credit being forged, fraudulent, invalid, insufficient or inaccurate in any respect or failing to comply with
the terms of such Letter of Credit or (C) any loss or delay, including in the transmission of any document, (ii) the existence of any setoff, claim, abatement, recoupment, defense or other right that any Person (including any Group Member)
may have against the beneficiary of any Letter of Credit or any other Person, whether in connection with any Loan Document or any other Contractual Obligation or transaction, or the existence of any other withholding, abatement or reduction,
(iii) in the case of the obligations of any Revolving Credit Lender, (A) the failure of any condition precedent set forth in Section 3.2 to be satisfied (each of which conditions precedent the Revolving Credit Lenders hereby
irrevocably waive) or (B) any adverse change in the condition (financial or otherwise) of any Loan Party and (iv) any other act or omission to act or delay of any kind of any Secured Party or any other Person or any other event or
circumstance whatsoever, whether or not similar to any of the foregoing, that might, but for the provisions of this Section 2.4, constitute a legal or equitable discharge of any obligation of the Borrower or any Revolving Credit Lender
hereunder. 
 Section 2.5 Reduction and Termination of the Commitments. 

(a) Optional. The Borrower may, upon notice to the Applicable Administrative Agent, terminate in whole or reduce in part ratably any
unused portion of the Revolving Credit Commitments; provided, however, that each partial reduction shall be in an aggregate amount that is an integral multiple of $1,000,000. 

(b) Mandatory. 

(i) The Total Commitment (and the Commitment of each Lender) shall terminate in its entirety on July 2, 2015, unless the
Closing Date has occurred on or prior to such date. 
 (ii) In addition to any other mandatory commitment reductions pursuant
to this Section 2.5(b), the Total A Term Loan Commitment (and the A Term Loan Commitment of each Lender) shall terminate in its entirety on the Closing Date (after giving effect to the incurrence of A Term Loans on such date). 

(iii) In addition to any other mandatory commitment reductions pursuant to this Section 2.5(b), the Total B Term
Loan Commitment (and the B Term Loan Commitment of each Lender) shall terminate in its entirety on the Closing Date (after giving effect to the incurrence of B Term Loans on such date). 

(iv) In addition to any other mandatory commitment reductions pursuant to this Section 2.5(b), the Total Revolving
Credit Commitment shall terminate in its entirety on the Revolving Credit Termination Date. 
 (v) Each reduction to, or
termination of, the Total Revolving Credit Commitment pursuant to this Section 2.5(b) shall be applied to proportionately reduce or terminate the Revolving Credit Commitment of each Lender with such a Commitment. 

(vi) Upon the incurrence of any Specified Refinancing Revolving Credit Commitments, the Revolving Credit Commitments of the
Revolving Credit Lenders under the Revolving Credit Commitments and Revolving Loans being refinanced shall be automatically and permanently reduced on a ratable basis by an amount equal to 100% of the Specified Refinancing Revolving Credit
Commitments so incurred. 

  
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 Section 2.6 Repayment of Loans. (a) The Borrower shall repay the entire
unpaid principal amount of each Tranche of Loans on the respective Maturity Date for such Tranche of Loans. 
 (b) In addition to any other
mandatory repayments pursuant to Section 2.8, on each date set forth below (each, a “Scheduled A Term Loan Repayment Date”), the Borrower shall be required to repay that principal amount of A Term Loans, to the
extent then outstanding, as is set forth opposite each such date below (each such repayment, as the same may be reduced as provided in Sections 2.12(a), 2.12(b) and 2.21, a “Scheduled A Term Loan Repayment”):

  

					
	 Scheduled A Term Loan Repayment Date
	  	Amount	 
	September 30, 2015	  	$	8,125,000	  
	December 31, 2015	  	$	8,125,000	  
	March 31, 2016	  	$	8,125,000	  
	June 30, 2016	  	$	8,125,000	  
	September 30, 2016	  	$	8,125,000	  
	December 31, 2016	  	$	8,125,000	  
	March 31, 2017	  	$	8,125,000	  
	June 30, 2017	  	$	8,125,000	  
	September 30, 2017	  	$	8,125,000	  
	December 31, 2017	  	$	8,125,000	  
	March 31, 2018	  	$	8,125,000	  
	June 30, 2018	  	$	8,125,000	  
	September 30, 2018	  	$	8,125,000	  
	December 31, 2018	  	$	8,125,000	  
	March 31, 2019	  	$	8,125,000	  
	June 30, 2019	  	$	8,125,000	  
	September 30, 2019	  	$	8,125,000	  
	December 31, 2019	  	$	8,125,000	  
	March 31, 2020	  	$	8,125,000	  
	Scheduled A Term Loan Maturity Date	  	$	495,625,000	  

  
 61 

 (c) In addition to any other mandatory repayments pursuant to Section 2.8, on each
date set forth below (each, a “Scheduled B Term Loan Repayment Date”), the Borrower shall be required to repay that principal amount of B Term Loans, to the extent then outstanding, as is set forth opposite each such date
below (each such repayment, as the same may be reduced as provided in Sections 2.12(a), 2.12(b) and 2.21, a “Scheduled B Term Loan Repayment”): 

 

					
	 Scheduled B

Term Loan Repayment Date
	  	Amount	 
	September 30, 2015	  	$	2,625,000	  
	December 31, 2015	  	$	2,625,000	  
	March 31, 2016	  	$	2,625,000	  
	June 30, 2016	  	$	2,625,000	  
	September 30, 2016	  	$	2,625,000	  
	December 31, 2016	  	$	2,625,000	  
	March 31, 2017	  	$	2,625,000	  
	June 30, 2017	  	$	2,625,000	  
	September 30, 2017	  	$	2,625,000	  
	December 31, 2017	  	$	2,625,000	  
	March 31, 2018	  	$	2,625,000	  
	June 30, 2018	  	$	2,625,000	  
	September 30, 2018	  	$	2,625,000	  
	December 31, 2018	  	$	2,625,000	  
	March 31, 2019	  	$	2,625,000	  
	June 30, 2019	  	$	2,625,000	  
	September 30, 2019	  	$	2,625,000	  
	December 31, 2019	  	$	2,625,000	  
	March 31, 2020	  	$	2,625,000	  
	June 30, 2020	  	$	2,625,000	  
	September 30, 2020	  	$	2,625,000	  
	December 31, 2020	  	$	2,625,000	  
	March 31, 2021	  	$	2,625,000	  
	June 30, 2021	  	$	2,625,000	  
	September 30, 2021	  	$	2,625,000	  
	December 31, 2021	  	$	2,625,000	  
	March 31, 2022	  	$	2,625,000	  
	Scheduled B Term Loan Maturity Date	  	$	979,125,000	  

  
 62 

 Section 2.7 Optional Prepayments. The Borrower may prepay the outstanding
principal amount of any Loan in whole or in part at any time, without any premium or penalty (except as set forth in Section 2.11(c) and subject to payment of any breakage costs that may be owing pursuant to Section 2.16(a)
after giving effect to such prepayment); provided, however, that (x) each partial prepayment that is not of the entire outstanding amount under any Facility shall be in an aggregate minimum amount of $5,000,000 and integral
multiples of $1,000,000 in excess thereof and (y) at the Borrower’s election, such prepayment shall not, so long as no Default or Event of Default then exists, be applied to the Revolving Loans of a Defaulting Lender. Optional partial
prepayment of Term Loans shall be applied in the manner set forth in Section 2.12(a). 
 Section 2.8 Mandatory
Prepayments. 
 (a) Excess Cash Flow. The Borrower shall pay or cause to be paid to the Administrative Agents, within 10 Business
Days after the last date Financial Statements can be delivered pursuant to Section 6.1(b) for any Fiscal Year ending on or after December 31, 2016, an amount equal to the remainder of (A) 50% of the Excess Cash Flow for such
Fiscal Year minus (B) the aggregate principal amount of all optional prepayments of Loans made pursuant to Section 2.7 or 2.21 and all mandatory prepayments of Revolving Loans pursuant to Section 2.8 (other
than clause (a)) (but (x) in the case of an optional prepayment of Revolving Loans or Swing Loans or any such mandatory prepayment of Revolving Loans, in each case, only to the extent accompanied by a corresponding permanent reduction in
the Revolving Credit Commitments and (y) in the case of any prepayments of Term Loans pursuant to Section 2.21, the amount deducted shall be limited to the amount of cash actually used to prepay principal of such outstanding Term
Loans) during such Fiscal Year, in each case, other than any such prepayments made with the proceeds of long-term Indebtedness (other than with Loans under the Revolving Credit Facility) or directly with proceeds received from the issuance of common
Stock or Preferred Stock of the Borrower; provided, however, in the event that the Consolidated Secured Leverage Ratio of the Borrower as of the end of any Fiscal Year, commencing with the Fiscal Year ending December 31, 2016, is
equal to or less than (x) 2.50:1.00, then such percentage for such Fiscal Year shall be reduced to 25% or (y) 2.00:1.00, then such percentage for such Fiscal Year shall be reduced to 0%. 

(b) Debt Issuances. (i) Upon receipt on or after the Closing Date by any Loan Party or any of its Subsidiaries of Net Cash
Proceeds arising from the incurrence by any Loan Party or any of its Subsidiaries of Indebtedness of the type specified in clause (a) or (b) of the definition thereof (other than any such Indebtedness permitted hereunder in
reliance upon Section 8.1), the Borrower shall immediately pay or cause to be paid to the Administrative Agents an aggregate amount equal to 100% of such Net Cash Proceeds. 

  
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 (ii) Upon the incurrence or issuance by the Borrower of any Specified Refinancing
Term Loans, the Borrower shall immediately pay or cause to be paid to the Applicable Administrative Agent an aggregate amount equal to 100% of the Net Cash Proceeds received therefrom to prepay an aggregate principal amount of the applicable Tranche
or Tranches of Term Loans that are to be refinanced with the proceeds of such Specified Refinancing Term Loans in accordance with Section 2.12. 

(c) Asset Sales and Property Loss Events. Upon receipt on or after the Closing Date by any Loan Party or any of its Subsidiaries of Net
Cash Proceeds arising from (i) any Sale by any Group Member of any of its property (other than Sales of its own Stock and Stock Equivalents and Excluded Sales, as defined below) to the extent the Net Cash Proceeds thereof exceed $25,000,000 in
any Fiscal Year (or, if the aggregate Net Cash Proceeds therefrom in any Fiscal Year is $25,000,000 or less, to the extent that the Net Cash Proceeds from any such Sale constitute an “asset sale” or similarly defined term for purposes of
any of the Existing Notes Indentures, any Permitted Refinancing thereof or any Permitted Additional Debt) (it being understood and agreed, however, that such $25,000,000 aggregate annual exclusion shall not apply to any of the Net Cash
Proceeds from any Designated Sale, all of which Net Cash Proceeds shall be subject to the provisions of this Section 2.8(c)); or (ii) any Property Loss Event with respect to any property of any Group Member to the extent resulting,
in the aggregate with all other such Property Loss Events, in the receipt by any of them of Net Cash Proceeds in excess of $25,000,000, the Borrower shall immediately pay or cause to be paid to the Administrative Agents an aggregate amount equal to
100% of such Net Cash Proceeds (or, with respect to Sales of property permitted hereunder in reliance upon clause (g) of Section 8.4, 50% of the Net Cash Proceeds); provided, however, (A) that, upon any
such receipt, as long as no Event of Default shall be continuing, any Group Member may make Permitted Reinvestments with such Net Cash Proceeds (other than with any Net Cash Proceeds received in connection with any Designated Sale, which Net Cash
Proceeds (or an amount equal thereto) shall, as promptly as practicable but in any event within 15 days of receipt by the Borrower or any Subsidiary thereof (or such later date, not beyond 30 days after receipt of such Net Cash Proceeds, as may be
approved by the Administrative Agents), be paid or caused to be paid to the Applicable Administrative Agent to be applied to the Obligations in accordance with Section 2.12(b)) and the Borrower shall not be required to make or cause such
payment to the extent (x) such Net Cash Proceeds are intended to be used to make Permitted Reinvestments and (y) on each Reinvestment Prepayment Date for such Net Cash Proceeds, the Borrower shall pay or cause to be paid to the
Administrative Agents an aggregate amount equal to the Reinvestment Prepayment Amount applicable to such Reinvestment Prepayment Date and such Net Cash Proceeds, and (B) that the Borrower may use a portion of such Net Cash Proceeds to prepay,
repurchase or redeem any Permitted Additional Debt that is secured on a pari passu basis with the Loans to the extent such Permitted Additional Debt and the Liens securing the same are permitted hereunder and the documentation governing such
Permitted Additional Debt requires such a prepayment or repurchase thereof with the proceeds of such Sale or Property Loss Event, in each case in an amount not to exceed the product of (x) the amount of such Net Cash Proceeds and (y) a
fraction, the numerator of which is the outstanding principal amount of such Permitted Additional Debt and the denominator of which is the aggregate outstanding principal amount of all Loans, L/C Obligations and all such Permitted Additional Debt
(it being understood and agreed that, to the extent any portion of such Net Cash Proceeds is not ultimately used to prepay, repurchase or redeem any such Permitted Additional Debt within the time period required by the respective Permitted
Additional Debt Documents, the Borrower shall pay or cause to be paid to the Administrative Agents within 3 Business Days after the end of such period 100% of the portion of such Net Cash Proceeds not so

  
 64 

 
used). “Excluded Sales” shall mean (i) Sales of property permitted hereunder in reliance upon any of clauses (a) through (d) and (f)(i) of
Section 8.4, and (ii) Sales of property permitted hereunder in reliance upon clauses (f)(ii) and (g) of Section 8.4 if after giving effect to any such Sale and any prepayment of Loans under this
Section 2.8(c) (on a Pro Forma Basis as of the last day of the last Fiscal Quarter for which Financial Statements have been delivered hereunder for the four Fiscal Quarter period ending on the last day of such Fiscal Quarter, as if such
Sale had occurred on the first day of such period), the Consolidated Secured Leverage Ratio of the Borrower is not greater than 4.00:1.00 (it being understood that prepayments from Sales of property permitted hereunder in reliance upon clauses
(f)(ii) and (g) of Section 8.4 shall only be required to the extent necessary to reduce the Consolidated Secured Leverage Ratio of the Borrower to 4.00:1.00); provided, however, to the extent that all or any
portion of the Net Cash Proceeds from any Excluded Sale would otherwise be required to be used to prepay, repurchase or redeem (or make an offer to prepay, repurchase or redeem) any Existing Notes or any Permitted Additional Debt or any Permitted
Refinancing of any of the foregoing, then such Net Cash Proceeds shall be applied as provided above in this Section 2.8(c) without regard to this sentence. 

(d) Excess Outstandings. On any date on which the aggregate principal amount of Revolving Credit Outstandings exceeds the aggregate
Revolving Credit Commitments, the Borrower shall pay to the Applicable Administrative Agent an amount equal to such excess. 
 (e)
Application of Payments. Any payments made to the Applicable Administrative Agent pursuant to this Section 2.8 shall be applied to the Obligations in accordance with Section 2.12(b). 

(f) No Premium or Penalty. Any mandatory prepayments under this Section 2.8 shall be made without any premium or penalty
(except as set forth in Section 2.11(c) in relation to any mandatory prepayment required pursuant to Section 2.8(b) above and subject to payment of any breakage costs that may be owing pursuant to Section 2.16(a)
after giving effect to such prepayment). 
 Section 2.9 Interest. 

(a) Rate. All Loans and the outstanding amount of all other Obligations (other than pursuant to Secured Hedging Agreements and Secured
Treasury Services Agreements) shall bear interest, in the case of Loans, on the unpaid principal amount thereof from the date such Loans are made and, in the case of such other Obligations, from the date such other Obligations are due and payable
until, in all cases, paid in full, except as otherwise provided in clause (c) below, as follows: (i) in the case of Base Rate Loans, at a rate per annum equal to the sum of the Base Rate and the Applicable Margin, each as in effect
from time to time, (ii) in the case of Eurodollar Rate Loans, at a rate per annum equal to the sum of the Eurodollar Rate and the Applicable Margin, each as in effect for the applicable Interest Period, and (iii) in the case of other
Obligations, at a rate per annum equal to the sum of the Base Rate and the Applicable Margin for Revolving Loans that are Base Rate Loans, each as in effect from time to time. 

(b) Payments. Interest accrued shall be payable in arrears (i) if accrued on the principal amount of any Loan, (A) at
maturity (whether by acceleration or otherwise), (B) if such Loan is a Term Loan, upon the payment or prepayment of the principal amount on which such interest has accrued and (C)(1) if such Loan is a Base Rate Loan (including a Swing Loan), on
the last day of each calendar quarter, (2) if such Loan is a Eurodollar Rate Loan, on the last 

  
 65 

 
day of each Interest Period applicable to such Loan and, if applicable, on each date during such Interest Period occurring every 3 months from the first day of such Interest Period and
(ii) if accrued on any other Obligation, on demand from the Applicable Administrative Agent after the time such Obligation is due and payable (whether by acceleration or otherwise). 

(c) Default Interest. Notwithstanding the rates of interest specified in clause (a) above or elsewhere in any Loan
Document, effective immediately upon (A) the occurrence of any Event of Default under Sections 9.1(a), 9.1(c)(i) (with respect to Article V only) or 9.1(e)(ii) or (B) the delivery of a notice by both
Administrative Agents (with a copy to the other Administrative Agent) or the Required Lenders (with a copy to the Administrative Agents) to the Borrower during the continuance of any other Event of Default and, in each case, for as long as such
Event of Default shall be continuing, the principal balance of all Obligations (including any Obligation that bears interest by reference to the rate applicable to any other Obligation) then due and payable shall bear interest at a rate that is
2% per annum in excess of the interest rate applicable to such Obligations from time to time, payable on demand or, in the absence of demand, on the date that would otherwise be applicable. 

(d) Maximum Lawful Rate. Notwithstanding anything to the contrary set forth in this Section 2.9, if a court of competent
jurisdiction determines in a final order that the rate of interest payable hereunder exceeds the highest rate of interest permissible under law (the “Maximum Lawful Rate”), then so long as the Maximum Lawful Rate would be so
exceeded, the rate of interest payable hereunder shall be equal to the Maximum Lawful Rate; provided, however, that if at any time thereafter the rate of interest payable hereunder is less than the Maximum Lawful Rate, the Borrower
shall continue to pay interest hereunder at the Maximum Lawful Rate until such time as the total interest received by Lenders is equal to the total interest that would have been received had the interest rate payable hereunder been (but for the
operation of this paragraph) the interest rate payable since the Closing Date as otherwise provided in this Agreement. Thereafter, interest hereunder shall be paid at the rate(s) of interest and in the manner provided in
clauses (a) through (c) of this Section 2.9, unless and until the rate of interest again exceeds the Maximum Lawful Rate, and at that time this paragraph shall again apply. In no event shall the total
interest received by any Lender pursuant to the terms hereof exceed the amount that such Lender could lawfully have received had the interest due hereunder been calculated for the full term hereof at the Maximum Lawful Rate. If the Maximum Lawful
Rate is calculated pursuant to this paragraph, such interest shall be calculated at a daily rate equal to the Maximum Lawful Rate divided by the number of days in the year in which such calculation is made. If, notwithstanding the provisions of this
Section 2.9(d), a court of competent jurisdiction shall finally determine that any Lender has received interest hereunder in excess of the Maximum Lawful Rate, such Lender shall, to the extent permitted by applicable law, promptly apply
such excess in the order specified in Section 2.12 and thereafter shall refund any excess to the Borrower or as a court of competent jurisdiction may otherwise order. 

Section 2.10 Conversion and Continuation Options. 

(a) Option. The Borrower may elect (i) in the case of any Eurodollar Rate Loan, (A) to continue such Eurodollar Rate Loan or
any portion thereof for an additional Interest Period on the last day of the Interest Period applicable thereto and (B) to convert such Eurodollar Rate Loan or any portion thereof into a Base Rate Loan at any time on any Business Day, subject
to the payment of any breakage costs required by Section 2.16(a), and (ii) in the case of Base Rate Loans (other than Swing Loans), to convert such Base Rate Loans or any portion thereof into Eurodollar Rate Loans at any time on any
Business Day upon 3 Business Days’ prior notice; 

  
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 provided, however, that, (x) for each Interest Period, the aggregate amount of Eurodollar Rate
Loans having such Interest Period must be an integral multiple of $1,000,000 and (y) no conversion in whole or in part of Base Rate Loans to Eurodollar Rate Loans and no continuation in whole or in part of Eurodollar Rate Loans shall be
permitted at any time at which (1) a Default or an Event of Default shall be continuing and the Applicable Administrative Agent or the Required Lenders shall have determined in their sole discretion not to permit such conversions or
continuations or (2) such continuation or conversion would be made during a suspension imposed by Section 2.15. 
 (b)
Procedure. Each such election shall be made by giving the Applicable Administrative Agent at least 3 Business Days’ prior notice in substantially the form of Exhibit F (a “Notice of Conversion or
Continuation”) duly completed. The Applicable Administrative Agent shall promptly notify each Lender in the applicable Facility of its receipt of a Notice of Conversion or Continuation and of the options selected therein. If the Applicable
Administrative Agent does not receive a timely Notice of Conversion or Continuation from the Borrower containing a permitted election to continue or convert any Eurodollar Rate Loan, then, upon the expiration of the applicable Interest Period, such
Loan shall be automatically converted to a Base Rate Loan. Each partial conversion or continuation shall be allocated ratably among the Lenders in the applicable Facility in accordance with their Pro Rata Shares. 

Section 2.11 Fees. 

(a) Unused Commitment Fees. The Borrower agrees to pay to each Revolving Credit Lender that is a Non-Defaulting Lender a commitment fee
on the actual daily amount by which the Revolving Credit Commitment of such Lender exceeds its Pro Rata Share of the sum of (i) the aggregate outstanding principal amount of Revolving Loans and (ii) the outstanding amount of the
L/C Obligations for all Letters of Credit (the “Unused Revolver Commitment Fee”) from the date hereof through the Revolving Credit Termination Date at a rate per annum equal to 0.50%, payable in arrears (x) on the last day
of each calendar quarter and (y) on the Revolving Credit Termination Date. 
 (b) Letter of Credit Fees. The Borrower agrees to
pay, with respect to all Letters of Credit issued by any L/C Issuer, (i) to such L/C Issuer, certain fees, documentary and processing charges as separately agreed between the Borrower and such L/C Issuer or otherwise in accordance with
such L/C Issuer’s standard schedule in effect at the time of determination thereof and (ii) to the Pro Rata Administrative Agent, for the benefit of the Revolving Credit Lenders according to their Pro Rata Shares, a fee accruing at a
rate per annum equal to the Applicable Margin for Revolving Loans that are Eurodollar Rate Loans on the maximum undrawn face amount of such Letters of Credit, payable in arrears (A) on the last day of each calendar quarter ending after the
issuance of such Letter of Credit and (B) on the Revolving Credit Termination Date; provided, however, that the fee payable under this clause (ii) shall be increased by 2.00% per annum and shall be payable, in
addition to being payable on any date it is otherwise required to be paid hereunder, on demand effective immediately upon (x) the occurrence of any Event of Default under Sections 9.1(a), 9.1(c)(i) (with respect to
Article V only) or Section 9.1(e)(ii) or (y) the delivery of a notice by either Administrative Agent (with copy to the other Administrative Agent) or the Required Lenders (with a copy to the Administrative Agents) to the
Borrower during the continuance of any other Event of Default and, in each case, for as long as such Event of Default shall be continuing. 

  
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 (c) Soft Call Protection on B Term Loans. At the time of the effectiveness of any
Repricing Event that is consummated on or prior to the sixth month anniversary of the Closing Date, the Borrower agrees to pay to the Applicable Administrative Agent, for the ratable account of each Term Lender with outstanding B Term Loans which
are repaid, prepaid or converted pursuant to such Repricing Event (including each Term Lender that withholds its consent to such Repricing Event and is replaced or repaid under Section 2.18), a fee in an amount equal to 1.00% of the
aggregate principal amount of all B Term Loans repaid, prepaid or converted in connection with such Repricing Event. Such fees shall be due and payable upon the date of the effectiveness of such Repricing Event. 

(d) Additional Fees. The Borrower has agreed to pay to the Administrative Agents and other Persons additional fees, the amount and
dates of payment of which are embodied in the Fee Letters and the Engagement Letter. 
 Section 2.12 Application of
Payments. 
 (a) Application of Voluntary Prepayments. Subject to Section 2.12(c), any prepayment of Term Loans
pursuant to Section 2.7 shall be applied (x) pro rata to the outstanding Tranches of Term Loans (with each Tranche of outstanding Term Loans to receive its Term Loan Percentage of the applicable prepayment) unless, in the case of
any Term Loans incurred after the Closing Date, the respective Lenders thereof agree to a lesser percentage as provided in the applicable Incremental Amendment, Extension Amendment or Refinancing Amendment, as the case may be; provided that,
notwithstanding the foregoing, in the case of any prepayment pursuant to Section 2.7, the Borrower may elect not to prepay Extended Loans pursuant to any Extension at a time when the existing Loans from which such Extended Loans were
extended are outstanding, and (y) to the remaining scheduled installments of the respective Tranche of Term Loans as directed by the Borrower at the time of the respective prepayment (and absent such direction, in direct order of maturity
thereof). 
 (b) Application of Mandatory Prepayments. Subject to the provisions of clause (c) below with respect to the
application of payments during the continuance of an Event of Default, any payment made by the Borrower to the Applicable Administrative Agent pursuant to Section 2.8 or any other prepayment of the Obligations required to be applied in
accordance with this clause (b) shall be applied (i) first (other than in respect of any payment required pursuant to Section 2.8(d)), (A) to repay on a pro rata basis the outstanding principal balance of the
Term Loans (with each Tranche of outstanding Term Loans to receive its Term Loan Percentage of the applicable repayment) unless either (x) such prepayment is to be made pursuant to Section 2.8(b)(ii), in which case, such prepayment
shall be applied solely to the Tranche of Term Loans to be refinanced with the Net Cash Proceeds from the incurrence of the respective Specified Refinancing Term Loans, or (y) in the case of any Term Loans incurred after the Closing Date, the
Lenders thereof agree to a lesser percentage as provided in the applicable Incremental Amendment, Extension Amendment or Refinancing Amendment, as the case may be (and, for the avoidance of doubt, to the extent that such Lenders elect a lesser
percentage, remaining amount shall be allocated to the other Tranches of Term Loans on a pro rata basis), and (B) to the extent applied to any Tranche of Term Loans, to reduce ratably the then remaining scheduled installments of each such
Tranche of Term Loans on a pro rata basis, (ii) second to repay the outstanding principal balance of the Revolving Loans and the Swing Loans (without any reduction in the Revolving Credit Commitments) and (iii) third, in the
case of any payment required pursuant to Section 2.8(d) to the extent that the outstanding L/C Obligations for all Letters of Credit exceed either the L/C Sublimit or the aggregate Revolving Credit Commitments,

  
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to provide cash collateral to the extent and in the manner provided in Section 9.3 and, then, any excess shall be retained by the Borrower; provided, however,
(x) with respect to up to $100,000,000 of aggregate principal repayments required to be made pursuant to Section 2.8(c) in connection with any Designated Sales, such principal prepayments may, at the Borrower’s option (and as
the Borrower chooses to allocate with respect to any Designated Sale or Sales in its discretion) and upon written notice to the Applicable Administrative Agent, first be applied toward the repayment of the outstanding principal balance of any
Revolving Loans and Swing Loans (without any reduction in the Revolving Credit Commitments) and (y) with respect to the remaining principal repayments required to be made pursuant to Section 2.8(c) in connection with any Designated
Sales (including, for the avoidance of doubt, any amounts not elected to be applied toward the Revolving Loans and Swing Loans pursuant to preceding clause (x)), such principal prepayments shall be applied as provided above in this
Section 2.12(b) without regard to this proviso. 
 (c) Application of Payments During an Event of Default. The Borrower
hereby irrevocably waives, and agrees to cause each Loan Party and each other Group Member to waive, the right to direct the application during the continuance of an Event of Default of any and all payments or prepayments in respect of any
Obligations and any proceeds of Collateral and agrees that, notwithstanding the provisions of clause (a) or (b) above, the Administrative Agents may, and, upon either (A) the direction of the Required Lenders or
(B) the termination of any Commitment or the acceleration of any Obligation pursuant to Section 9.2, shall, apply all payments in respect of any Obligations, all funds on deposit in any Cash Collateral Account and all other proceeds
of Collateral (i) first, to pay Obligations in respect of any cost or expense reimbursements, fees or indemnities then due to the Agents, (ii) second, to pay Obligations in respect of any cost or expense reimbursements, fees
or indemnities then due to the Lenders and the L/C Issuers, (iii) third, to pay interest then due and payable in respect of the Loans and L/C Reimbursement Obligations, (iv) fourth, to repay the outstanding principal amounts
of the Loans and L/C Reimbursement Obligations, to provide cash collateral for Letters of Credit in the manner and to the extent described in Sections 2.20 and 9.3 and to pay amounts owing with respect to Secured Hedging
Agreements and Secured Treasury Services Agreements and (v) fifth, to the payment of all other Obligations. 
 (d)
Application of Payments Generally. All payments that would otherwise be allocated to the Revolving Credit Lenders pursuant to this Section 2.12 shall instead be allocated first, to repay interest on Swing Loans, on any
portion of the Revolving Loans that the Applicable Administrative Agent may have advanced on behalf of any Lender and on any L/C Reimbursement Obligation, in each case for which the Applicable Administrative Agent or, as the case may be, the
L/C Issuer has not then been reimbursed by such Lender or the Borrower, second, to pay the outstanding principal amount of the foregoing obligations and third, to repay the Revolving Loans. All payments and prepayments of any Revolving
Loans or Term Loans shall be applied first, to repay such Loans outstanding as Base Rate Loans and second, to repay such Loans outstanding as Eurodollar Rate Loans, with those Eurodollar Rate Loans having earlier expiring Interest
Periods being repaid prior to those having later expiring Interest Periods. All payments and prepayments of Term Loans shall be applied to reduce ratably the remaining installments of such outstanding principal amounts of the Term Loans
(provided that any voluntary prepayment of Term Loans shall be applied as set forth in clause (a) of this Section 2.12). If sufficient amounts are not available to repay all outstanding Obligations described in any
priority level set forth in this Section 2.12, the available amounts shall be applied, unless otherwise expressly specified herein, to such Obligations ratably based on the 

  
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proportion of the Secured Parties’ interest in such Obligations. Any priority level set forth in this Section 2.12 that includes interest shall include all such interest, whether
or not accruing after the filing of any petition in bankruptcy or the commencement of any insolvency, reorganization or similar proceeding, and whether or not a claim for post-filing or post-petition interest is allowed in any such proceeding 

(e) Application of Prepayments among the Administrative Agents. Subject to the provisions of clause (c) above, any payments
required to be made by the Borrower to the Administrative Agents pursuant to Section 2.7 or 2.8 and applied in accordance with the provisions of this Section 2.12 or any other prepayment required to be made pursuant to
this Agreement shall be paid by the Borrower to the Applicable Administrative Agent and, in the case of any prepayment of principal of Term Loans which is to be applied to more than one Tranche of Term Loans, the Borrower shall pay to the Applicable
Administrative Agent the Term Loan Percentage of the applicable prepayment in respect of each such Tranche of outstanding Term Loans. 

Section 2.13 Payments and Computations. 

(a) Procedure. (i) The Borrower shall make each payment under any Loan Document not later than 12:00 noon on the day when due to
the Applicable Administrative Agent by wire transfer to the following account (or at such other account or by such other means to such other address as the Applicable Administrative Agent shall have notified the Borrower in writing within a
reasonable time prior to such payment) in immediately available Dollars and without setoff or counterclaim: 
  

	 	(A)	in the case the Pro Rata Administrative Agent: 

 ABA No.: 021-001-033 

Account Number: 50-271-079 

Deutsche Bank Trust Company of Americas, New York, New York: 

Account Name: HH Cash Collection Account 

Reference: HFS6713/Alere, Inc. 
  

	 	(B)	in the case the B Term Loan Administrative Agent: 

 SWIFT CODE: CITIUS33 

ABA No.: 021000089 
 Account
Number: 30627664 
 Citibank N.A., New York, New York 

A/C#: 30627664 
 Account Name:
Alere Inc. 
 Reference: 039568324 
 The
Applicable Administrative Agent shall promptly thereafter cause to be distributed immediately available funds relating to the payment of principal, interest or fees to the Lenders, in accordance with the application of payments set forth in
Section 2.12. 
 (ii) The Lenders shall make any payment under any Loan Document in immediately available Dollars and without
setoff or counterclaim. Each Revolving Credit Lender shall make each payment for the account of any L/C Issuer or Swingline Lender required pursuant to 

  
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Section 2.3 or 2.4 (A) if the notice or demand therefor was received by such Lender prior to 11:00 a.m. on any Business Day, on such Business Day and
(B) otherwise, on the Business Day following such receipt. 
 (iii) Payments received by the Applicable Administrative Agent after
12:00 noon, in the case of clause (i) above, or 11:00 a.m., in the case of clause (ii) above, shall be deemed to be received on the next Business Day. 

(b) Computations of Interests and Fees. All computations of interest and of fees shall be made by the Administrative Agents on the
basis of a year of 360 days (or, in the case of Base Rate Loans, the interest rate on which is determined by reference to clause (a) of the definition of Base Rate, 365/366 days), in each case for the actual number of days (including the
first day but excluding the last day) occurring in the period for which such interest and fees are payable. Each determination of an interest rate or the amount of a fee hereunder shall be made by the Applicable Administrative Agent (including
determinations of a Eurodollar Rate or Base Rate in accordance with the definitions of “Eurodollar Rate” and “Base Rate”, respectively) and shall be conclusive, binding and final for all purposes, absent manifest error. 

(c) Payment Dates. Whenever any payment hereunder shall be stated to be due on a day other than a Business Day, the due date for such
payment shall be extended to the next succeeding Business Day without any increase in such payment as a result of additional interest or fees; provided, however, that such interest and fees shall continue accruing as a result of such
extension of time. 
 (d) Advancing Payments. Unless the Applicable Administrative Agent shall have received notice from the Borrower
prior to the date on which any payment is due to the Applicable Administrative Agent hereunder that the Borrower will not make such payment in full, the Applicable Administrative Agent may assume that the Borrower has made such payment in full to
the Applicable Administrative Agent on such date and the Applicable Administrative Agent may, in reliance upon such assumption, cause to be distributed to each Lender on such due date an amount equal to the amount then due such Lender. If and to the
extent that the Borrower shall not have made such payment in full to the Applicable Administrative Agent, each Lender shall repay to the Applicable Administrative Agent on demand such amount distributed to such Lender together with interest thereon
(at the Federal Funds Rate for the first Business Day and thereafter, at the rate applicable to Base Rate Loans under the applicable Facility) for each day from the date such amount is distributed to such Lender until the date such Lender repays
such amount to the Applicable Administrative Agent. 
 Section 2.14 Evidence of Debt. 

(a) Records of Lenders. Each Lender shall maintain in accordance with its usual practice accounts evidencing Indebtedness of the
Borrower to such Lender resulting from each Loan of such Lender from time to time, including the amounts of principal and interest payable and paid to such Lender from time to time under this Agreement. In addition, each Lender having sold a
participation in any of its Obligations or having identified an SPV as such to the Applicable Administrative Agent, acting as agent of the Borrower solely for this purpose and solely for U.S. federal income tax purposes, shall establish and maintain
at its address referred to in Section 11.11 (or at such other address as such Lender shall notify the Borrower) a record of ownership, in which such Lender shall register by book entry (A) the name and address of each such
participant and SPV (and each change thereto, whether by assignment or otherwise) and 

  
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(B) the rights, interest or obligation of each such participant and SPV in any Obligation, in any Commitment and in any right to receive any payment hereunder; provided that no Lender
shall have any obligation to disclose all or any portion of such information to any Person (including the identity of any SPV or Person who purchases a participation in any Obligation or any information relating to either the SPV’s or Person
who purchases a participation’s interest in any Commitments, Loans, L/C Obligations or its other obligations under any Loan Document) except to the extent that the relevant parties, in good faith, determine that such disclosure is necessary to
establish that such interest in a Commitment, Loan, L/C Obligation or other obligation is in “registered form” under Section 163(f), 871(h)(2) and 881(c)(2) of the Code and any related regulations (and any successor provisions).
Unless otherwise required by the IRS, any disclosure required by the foregoing sentence shall be made by the relevant Lender directly and solely to the IRS. The entries in the records maintained by a Lender shall be conclusive and binding absent
manifest error, and such Lender shall treat each Person whose name is recorded in their records as the owner of such interest in any Commitments, Loans, L/C Obligations or other obligations under any Loan Document for all purposes of this Agreement
notwithstanding any notice to the contrary. 
 (b) Records of the Applicable Administrative Agent. The Applicable Administrative
Agent, acting as agent of the Borrower solely for U.S. federal income tax purposes and solely with respect to the actions described in this Section 2.14, shall establish and maintain at its address referred to in
Section 11.11 (or at such other address as the Applicable Administrative Agent may notify the Borrower) (A) a record of ownership (each, a “Register”) in which the Applicable Administrative Agent agrees to register
by book entry the interests (including any rights to receive payment hereunder) of the Applicable Administrative Agent, each Lender and each L/C Issuer in the applicable Term Loans and the Revolving Credit Outstandings, each of their obligations
under this Agreement to participate in each Loan, Letter of Credit and L/C Reimbursement Obligation, and any assignment of any such interest, obligation or right and (B) accounts in the Register in accordance with its usual practice in
which it shall record (1) the names and addresses of the Lenders and the L/C Issuers (and each change thereto pursuant to Section 2.18 and Section 11.2, (2) the Commitments of each Lender, (3) the amount of
each Loan and each funding of any participation described in clause (A) above, and for Eurodollar Rate Loans, the Interest Period applicable thereto, (4) the amount of any principal or interest due and payable or paid, (5) the
amount of the L/C Reimbursement Obligations due and payable or paid and (6) any other payment received by the Applicable Administrative Agent from the Borrower and its application to the Obligations. 

(c) Registered Obligations. Notwithstanding anything to the contrary contained in this Agreement, the Loans (including any Notes
evidencing such Loans and, in the case of Revolving Loans, the corresponding obligations to participate in L/C Obligations and Swing Loans) and the L/C Reimbursement Obligations are registered obligations, the right, title and interest of the
Lenders and the L/C Issuers and their assignees in and to such Loans or L/C Reimbursement Obligations, as the case may be, shall be transferable only upon notation of such transfer in the Register and no assignment thereof shall be effective
until recorded therein. This Section 2.14 and Section 11.2 shall be construed so that the Loans and L/C Reimbursement Obligations are at all times maintained in “registered form” within the meaning of
Sections 163(f), 871(h)(2) and 881(c)(2) of the Code and any related regulations (and any successor provisions). 

  
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 (d) Prima Facie Evidence. The entries made in each Register and in the accounts maintained
pursuant to clauses (a) and (b) above shall, to the extent permitted by applicable Requirements of Law, be prima facie evidence of the existence and amounts of the obligations recorded therein; provided,
however, that no error in such account and no failure of any Lender or the Applicable Administrative Agent to maintain any such account shall affect the obligations of any Loan Party to repay the Loans in accordance with their terms. In
addition, the Loan Parties, each Administrative Agent, the Lenders and the L/C Issuers shall treat each Person whose name is recorded in each Register as a Lender or L/C Issuer, as applicable, for all purposes of this Agreement. Information
contained in each Register with respect to any Lender or any L/C Issuer shall be available for access by the Borrower, each Administrative Agent, such Lender or such L/C Issuer at any reasonable time and from time to time upon reasonable prior
notice. No Lender or L/C Issuer shall, in such capacity, have access to or be otherwise permitted to review any information in any Register other than information with respect to such Lender or L/C Issuer unless otherwise agreed by the
Administrative Agents. 
 (e) Notes. Upon any Lender’s request, the Borrower shall promptly execute and deliver Notes to such
Lender evidencing the Loans of such Lender in a Facility, and substantially in the form of Exhibit B-1, B-2, B-3 or B-4, as applicable; provided, however, that only one Note for each Facility shall be
issued to each Lender, except (i) to an existing Lender exchanging existing Notes to reflect changes in the applicable Register relating to such Lender, in which case the new Notes delivered to such Lender shall be dated the date of the
original Notes and (ii) in the case of loss, destruction or mutilation of existing Notes and similar circumstances. Each Note, if issued, shall only be issued as means to evidence the right, title or interest of a Lender or a registered
assignee in and to the related Loan, as set forth in the Register, and in no event shall any Note be considered a bearer instrument or obligation. 

Section 2.15 Suspension of Eurodollar Rate Option. Notwithstanding any provision to the contrary in this
Article II, the following shall apply: 
 (a) Interest Rate Unascertainable, Inadequate or Unfair. In the event that
(A) the Applicable Administrative Agent determines that adequate and fair means do not exist for ascertaining the applicable interest rates by reference to which the Eurodollar Rate is determined or (B) the Required Lenders notify the
Applicable Administrative Agent that the Eurodollar Rate for any Interest Period will not adequately reflect the cost to the Lenders of making or maintaining such Loans for such Interest Period, the Applicable Administrative Agent shall promptly so
notify the Borrower and the Lenders, whereupon the obligation of each Lender to make or to continue Eurodollar Rate Loans shall be suspended as provided in clause (c) below until the Applicable Administrative Agent shall notify the
Borrower that the Required Lenders have determined that the circumstances causing such suspension no longer exist. 
 (b) Illegality.
If any Lender determines that the introduction of, or any change in or in the interpretation of, any Requirement of Law after the date of this Agreement shall make it unlawful, or any Governmental Authority shall assert that it is unlawful, for
any Lender or its applicable lending office to make Eurodollar Rate Loans or to continue to fund or maintain Eurodollar Rate Loans, then, on notice thereof and demand therefor by such Lender to the Borrower through the Applicable
Administrative Agent, the obligation of such Lender to make or to continue Eurodollar Rate Loans shall be suspended as provided in clause (c) below until such Lender shall, through the Applicable Administrative Agent, notify the Borrower that
it has determined that it may lawfully make Eurodollar Rate Loans. 

  
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 (c) Effect of Suspension. If the obligation of any Lender to make or to continue
Eurodollar Rate Loans is suspended, (A) the obligation of such Lender to convert Base Rate Loans into Eurodollar Rate Loans shall be suspended, (B) such Lender shall make a Base Rate Loan at any time such Lender would otherwise be
obligated to make a Eurodollar Rate Loan, (C) the Borrower may revoke any pending Notice of Borrowing or Notice of Conversion or Continuation to make or continue any Eurodollar Rate Loan or to convert any Base Rate Loan into a Eurodollar Rate
Loan and (D) each Eurodollar Rate Loan of such Lender shall automatically and immediately (or, in the case of any suspension pursuant to clause (a) above, on the last day of the current Interest Period thereof) be converted into a
Base Rate Loan. 
 Section 2.16 Breakage Costs; Increased Costs; Capital Requirements. 

(a) Breakage Costs. The Borrower shall compensate each Lender, upon demand from such Lender to the Borrower (with copy to the Applicable
Administrative Agent), for all Liabilities (including, in each case, those incurred by reason of the liquidation or reemployment of deposits or other funds acquired by such Lender to prepare to fund, to fund or to maintain the Eurodollar Rate Loans
of such Lender to the Borrower but excluding any loss of the Applicable Margin on the relevant Loans) that such Lender may incur (A) to the extent, for any reason other than solely by reason of such Lender being a Non-Funding Lender, a proposed
Borrowing, conversion into or continuation of Eurodollar Rate Loans does not occur on a date specified therefor in a Notice of Borrowing or a Notice of Conversion or Continuation or in a similar request made by telephone by the Borrower, (B) to
the extent any Eurodollar Rate Loan is paid (whether through a scheduled, optional or mandatory prepayment) or converted to a Base Rate Loan (including because of Section 2.15) on a date that is not the last day of the applicable
Interest Period or (C) as a consequence of any failure by the Borrower to repay Eurodollar Rate Loans when required by the terms hereof. For purposes of this clause (a), each Lender shall be deemed to have funded each Eurodollar Rate
Loan made by it using a matching deposit or other borrowing in the London interbank market. 
 (b) Increased Costs. If at any time
any Lender or L/C Issuer determines that, after the later of (x) the date hereof and (y) the date such Lender or L/C Issuer entered into this Agreement (including by assignment) as such, the adoption of, or any change in or in the
interpretation, implementation, application or administration of, or compliance with, any Requirement of Law (other than any imposition or increase of Eurodollar Reserve Requirements) from any Governmental Authority shall have the effect of
(i) increasing the cost to such Lender of making, funding or maintaining any Eurodollar Rate Loan or to agree to do so or of participating, or agreeing to participate, in extensions of credit, (ii) increasing the cost to such L/C Issuer of
Issuing or maintaining any Letter of Credit or of agreeing to do so or (iii) imposing any other cost to such Lender or L/C Issuer with respect to compliance with its obligations under any Loan Document, then, upon demand by such Lender or L/C
Issuer (with copy to the Applicable Administrative Agent), the Borrower shall pay to the Applicable Administrative Agent for the account of such Lender or L/C Issuer amounts sufficient to compensate such Lender or L/C Issuer for such increased cost.

 (c) Increased Capital Requirements. If at any time any Lender or L/C Issuer determines that, after the later of (x) the date
hereof and (y) the date such Lender or L/C Issuer entered into this Agreement (including by assignment) as such, the adoption of, or any change in or in the interpretation, implementation, application or administration of, or compliance with,
any Requirement of Law (other than any imposition or increase of Eurodollar Reserve Requirements) from any Governmental Authority regarding capital adequacy, reserves, special deposits, 

  
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liquidity, compulsory loans, insurance charges against property of, deposits with or for the account of, Obligations owing to, or other credit extended or participated in by, any Lender or L/C
Issuer or any similar requirement (in each case other than any imposition or increase of Eurodollar Reserve Requirements) shall have the effect of reducing the rate of return on the capital of such Lender or L/C Issuer (or any corporation
controlling such Lender or L/C Issuer) as a consequence of its obligations under or with respect to any Loan Document or Letter of Credit to a level below that which, taking into account the capital adequacy policies of such Lender, L/C Issuer or
corporation, such Lender, L/C Issuer or corporation could have achieved but for such adoption or change, then, upon demand from time to time by such Lender or L/C Issuer (with a copy of such demand to the Applicable Administrative Agent), the
Borrower shall pay to the Applicable Administrative Agent for the account of such Lender amounts sufficient to compensate such Lender for such reduction. 

(d) Compensation Certificate. Each demand for compensation under this Section 2.16 shall be accompanied by a certificate of
the Lender or L/C Issuer claiming such compensation, setting forth in reasonable detail the amounts to be paid hereunder, which certificate shall be conclusive, binding and final for all purposes, absent manifest error. In determining such amount,
such Lender or L/C Issuer may use any reasonable averaging and attribution methods. 
 (e) Specified Regulations. Notwithstanding
anything in this Agreement to the contrary, (x) the Dodd-Frank Wall Street Reform and Consumer Protection Act and all requests, rules, guidelines or directives thereunder or issued in connection therewith and (y) all requests, rules,
guidelines or directives promulgated by the Bank for International Settlements, the Basel Committee on Banking Supervision (or any successor or similar authority) or the United States or foreign regulatory authorities, in each case pursuant to Basel
III, shall in each case be deemed to be a change after the Closing Date in a requirement of law or governmental rule, regulation or order, regardless of the date enacted, adopted, issued or implemented for all purposes under or in connection with
this Agreement (including this Section 2.16). 
 (f) Lookback Limitations. Notwithstanding anything to the contrary in
this Section 2.16, the Borrower shall not be required to compensate a Lender pursuant to this Section 2.16 for any amounts incurred more than 270 days prior to the date that such Lender notifies the Borrower of such
Lender’s intention to claim compensation therefor; provided that, if the circumstances giving rise to such claim have a retroactive effect, then such 270-day period shall be extended to include the period of such retroactive effect. 

Section 2.17 Taxes. 

(a) Payments Free and Clear of Taxes. Except as otherwise provided in this Section 2.17, each payment by any Loan Party
under any Loan Document shall be made free and clear of all Taxes. “Taxes” shall mean all present or future taxes and levies, imposts, deductions, charges or withholdings that in each case are imposed by a Governmental Authority,
including any interest, additions to tax or penalties applicable thereto, but excluding any (i) taxes measured by net income (including branch profits or similar taxes) and franchise taxes imposed in lieu of net income taxes, in each case
imposed on any Secured Party as a result of a present or former connection between such Secured Party and the jurisdiction of the Governmental Authority imposing such tax or any political subdivision or taxing authority thereof or therein (other
than such connection arising solely from any Secured Party having executed, delivered or performed its obligations or received a payment under, received or perfected a security interest under, or 

  
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enforced or become a party to or engaged in any other transactions pursuant to or sold or assigned an interest in any Loan Document), (ii) United States federal withholding taxes to the
extent that the obligation to withhold amounts existed on the date that such Secured Party became a “Secured Party” hereunder or designates a new lending office, except to the extent such Secured Party is a direct or indirect assignee
(other than pursuant to clause (iii) of Section 2.18(a) (Substitution of Lenders)) of any other Secured Party that was entitled, at the time the assignment from such other Secured Party became effective, to receive additional
amounts under this clause, (iii) taxes (including withholding taxes) that would not have been imposed but for the failure by any Secured Party to deliver the documentation required to be delivered pursuant to clause (f) below,
(iv) any U.S. federal withholding Taxes imposed under FATCA and (v) Other Taxes. 
 (b) Gross-Up. If any Taxes shall be
required by law to be deducted from or in respect of any amount payable under any Loan Document (other than any Secured Hedging Agreement or any Secured Treasury Services Agreement) to any Secured Party (i) such amount shall be increased as
necessary to ensure that, after all required deductions for such Taxes are made (including deductions applicable to any increases to any amount under this Section 2.17), such Secured Party receives the amount it would have received had
no such deductions been made, (ii) the relevant Loan Party shall make such deductions, (iii) the relevant Loan Party shall timely pay the full amount deducted to the relevant taxing authority or other authority in accordance with
applicable Requirements of Law and (iv) within 30 days after such payment is made, or as soon as practicable thereafter, the relevant Loan Party shall deliver to the Administrative Agents an original or certified copy of a receipt evidencing
such payment. 
 (c) Other Taxes. In addition, the Borrower agrees to pay, and authorizes the Applicable Administrative Agent to pay
in its name, any stamp, documentary, excise or property tax, charges or similar levies imposed by any applicable Requirement of Law or Governmental Authority and all Liabilities with respect thereto (including by reason of any delay in payment
thereof), in each case arising from the execution, delivery or registration of, or otherwise with respect to, any Loan Document or any transaction contemplated therein (collectively, “Other Taxes”). The Swingline Lender may, without
any need for notice, demand or consent from the Borrower, by making funds available to the Applicable Administrative Agent in the amount equal to any such payment, make a Swing Loan to the Borrower in such amount, the proceeds of which shall be used
by Applicable Administrative Agent in whole to make such payment. Within 30 days after the date of any payment of Taxes or Other Taxes by any Loan Party, the Borrower shall furnish to the Applicable Administrative Agent, at its address referred to
in Section 11.11, the original or a certified copy of a receipt evidencing payment thereof. 
 (d) Indemnification of Secured
Parties. The Borrower shall reimburse and indemnify, within 30 days after receipt of demand therefor (with copy to the Administrative Agents), each Secured Party for all Taxes and Other Taxes (including any Taxes and Other Taxes imposed by any
jurisdiction on amounts payable under this Section 2.17) paid by such Secured Party and any Liabilities arising therefrom or with respect thereto to a Governmental Authority, whether or not such Taxes or Other Taxes were correctly or
legally asserted. A certificate of the Secured Party (or of the Applicable Administrative Agent on behalf of such Secured Party) claiming any compensation under this clause (d), setting forth the amounts to be paid thereunder and delivered to
the Borrower with copy to the Administrative Agents, shall be conclusive, binding and final for all purposes, absent manifest error. In determining such amount, the Applicable Administrative Agent and such Secured Party may use any reasonable
averaging and attribution methods. 

  
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 (e) Indemnification of Administrative Agents. Each Lender shall severally indemnify each
of the Administrative Agents, within 10 days after demand therefor, for (i) any Taxes attributable to such Lender (but only to the extent that any Loan Party has not already indemnified such Administrative Agent for such Taxes and without
limiting the obligation of the Loan Parties to do so), (ii) any taxes attributable to such Lender’s failure to comply with the provisions of Section 2.14 relating to the maintenance of a record of participants and SPVs and
(iii) any present or future taxes and levies, imposts, deductions, charges or withholdings that are in each case imposed by a Governmental Authority that are not included in the definition of Taxes (“Excluded Taxes”)
attributable to such Lender, in each case, that are payable or paid by an Administrative Agent in connection with any Loan Document, and any reasonable expenses arising therefrom or with respect thereto, whether or not such Excluded Taxes were
correctly or legally imposed or asserted by the relevant Governmental Authority. A certificate as to the amount of such payment or liability delivered to any Lender by an Administrative Agent shall be conclusive absent manifest error. Each Lender
hereby authorizes each Administrative Agent to set off and apply any and all amounts at any time owing to such Lender under any Loan Document or otherwise payable by an Administrative Agent to the Lender from any other source against any amount due
to an Administrative Agent under this clause (e). 
 (f) Mitigation. Any Lender claiming any additional amounts payable
pursuant to this Section 2.17 shall use its reasonable efforts (consistent with its internal policies and Requirements of Law) to file any certificate or document reasonably requested in writing by Borrower or to change the jurisdiction
of its lending office if, in the sole determination of such Lender, such a change would reduce any such additional amounts (or any similar amount that may thereafter accrue) and would not subject such Lender to any unreimbursed cost or expense or be
otherwise disadvantageous to such Lender. 
 (g) Refunds. If any party determines, in its sole discretion exercised in good faith,
that it has received a refund of any taxes as to which it has been indemnified pursuant to this Section 2.17 (including by the payment of additional amounts pursuant to this Section 2.17), it shall pay to the indemnifying
party an amount equal to such refund (but only to the extent of indemnity payments made under this Section 2.17 with respect to the taxes giving rise to such refund), net of all out-of-pocket expenses (including taxes) of such
indemnified party and without interest (other than any interest paid by the relevant Governmental Authority with respect to such refund). Such indemnifying party, upon the request of such indemnified party, shall repay to such indemnified party the
amount paid over pursuant to this clause (g) (plus any penalties, interest or other charges imposed by the relevant Governmental Authority) in the event that such indemnified party is required to repay such refund to such Governmental
Authority. Notwithstanding anything to the contrary in this clause (g), in no event will the indemnified party be required to pay any amount to an indemnifying party pursuant to this clause (g) the payment of which would place the
indemnified party in a less favorable net after-tax position than the indemnified party would have been in if the tax subject to indemnification and giving rise to such refund had not been deducted, withheld or otherwise imposed and the
indemnification payments or additional amounts with respect to such tax had never been paid. This clause (g) shall not be construed to require any indemnified party to make available its Tax Returns (or any other information relating to
its taxes that it deems confidential) to the indemnifying party or any other Person. 
 (h) Tax Forms. (i) Each Non-U.S. Lender
Party that, at any of the following times, is entitled to an exemption from United States withholding tax or, after a change in any 

  
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Requirement of Law, is subject to such withholding tax at a reduced rate under an applicable tax treaty, shall (w) on or prior to the date such Non-U.S. Lender Party becomes a “Non-U.S.
Lender Party” hereunder, (x) on or prior to the date on which any such form or certification expires or becomes obsolete, (y) after the occurrence of any event requiring a change in the most recent form or certification previously
delivered by it pursuant to this subclause (h) (i) and (z) from time to time if requested by the Borrower or either Administrative Agent (or, in the case of a participant or SPV, the relevant Lender), provide the Administrative Agents
and the Borrower (or, in the case of a participant or SPV, the relevant Lender) with two completed originals of each of the following, as applicable: (A) Forms W-8ECI (claiming exemption from U.S. withholding tax because the income is
effectively connected with a U.S. trade or business), W-8BEN or W-8BEN-E, as applicable (claiming exemption from, or a reduction of, U.S. withholding tax under an income tax treaty), or any successor forms, (B) in the case of a Non-U.S. Lender
Party claiming exemption under Sections 871(h) or 881(c) of the Code, IRS Form W-8BEN or W-8BEN-E, as applicable (claiming exemption from U.S. withholding tax under the portfolio interest exemption), or any successor form and a certificate in
substantially in the form of Exhibit I-1 (or Lender, in the case of a participant or SPV) that such Non-U.S. Lender Party is not (1) a “bank” within the meaning of Section 881(c)(3)(A) of the Code, (2) a “10 percent
shareholder” of the Borrower within the meaning of Section 881(c)(3)(B) of the Code or (3) a “controlled foreign corporation” described in Section 881(c)(3)(C) of the Code, (C) any other applicable document
prescribed by the IRS certifying as to the entitlement of such Non-U.S. Lender Party to such exemption from U.S. withholding tax or reduced rate with respect to all payments to be made to such Non-U.S. Lender Party under the Loan Documents or
(D) to the extent a Non-U.S. Lender Party is not the beneficial owner, executed copies of IRS Form W-8IMY, accompanied by IRS Form W-8ECI, W-8BEN or W-8BEN-E, as applicable, a certificate substantially in the form of Exhibit I-2 or Exhibit
I-3, IRS Form W-9, and/or other certification documents from each beneficial owner, as applicable; provided that if the Non-U.S. Lender Party is a partnership and one or more direct or indirect partners of such Non-U.S. Lender Party are
claiming the portfolio interest exemption, such Non-U.S. Lender Party may provide a certificate substantially in the form of Exhibit I-4 on behalf of each such direct and indirect partner. In addition, each Non-U.S. Lender Party shall, in the case
of any payment subject to FATCA in respect of any Loan, Letters of Credit, Note or Obligation, provide any forms, documentation, or other information as shall be prescribed by the IRS to demonstrate that the relevant Non-U.S. Lender Party has
complied with the applicable reporting requirements of FATCA so that such payments made to such Non-U.S. Lender Party hereunder would not be subject to U.S. federal withholding taxes imposed by FATCA. Unless the Borrower and the Administrative
Agents have received forms or other documents satisfactory to them indicating that payments under any Loan Document to or for a Non-U.S. Lender Party are not subject to United States withholding tax or are subject to such tax at a rate reduced by an
applicable tax treaty, the Loan Parties and the Administrative Agents shall withhold amounts required to be withheld by applicable Requirements of Law from such payments at the applicable statutory rate. 

(ii) Each U.S. Lender Party shall (A) on or prior to the date such U.S. Lender Party becomes a “U.S. Lender
Party” hereunder, (B) on or prior to the date on which any such form or certification expires or becomes obsolete, (C) after the occurrence of any event requiring a change in the most recent form or certification previously delivered
by it pursuant to this clause (h) and (D) from time to time if requested by the Borrower or either Administrative Agent (or, in the case of a participant or SPV, the relevant Lender), provide the Administrative Agents and the
Borrower (or, in the case of a participant or SPV, the relevant Lender) with two completed originals of Form W-9 (certifying that such U.S. Lender Party is entitled to an exemption from U.S. backup withholding tax) or any successor form. 

  
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 Notwithstanding the foregoing, a U.S. Lender Party and a Non-U.S. Lender Party shall be treated
as having complied with the requirements and delivered the documentation required by this clause (h) if, after the time such U.S. Lender Party or Non-U.S. Lender Party has become a Lender hereunder, a change in a Requirement of Law or
change in circumstance with respect to the Borrower subjects any such Lender to taxes (including withholding taxes) and such Lender is unable to provide the forms herein allowing for an exemption from or reduction in such taxes. 

Section 2.18 Substitution of Lenders. 

(a) Substitution Right. In the event that any Lender in any Facility that is not an Affiliate of either Administrative Agent (an
“Affected Lender”) (i) makes a claim under clause (b) or (c) of Section 2.16, (ii) notifies the Borrower pursuant to Section 2.15(b) that it becomes illegal for such Lender
to continue to fund or make any Eurodollar Rate Loan in such Facility, (iii) makes a claim for payment pursuant to Section 2.17(b), (iv) becomes a Defaulting Lender, (v) does not consent to any amendment, waiver or consent
to any Loan Document for which the consent of the Required Lenders is obtained but that requires the consent of other Lenders in such Facility or (vi) does not agree to any Extension Amendment with respect to any of its Loans or Commitments
pursuant to a request by the Borrower in accordance with Section 2.23, the Borrower may either pay in full such Affected Lender with respect to amounts due in such Facility with the consent of the Applicable Administrative Agent or
substitute for such Affected Lender in such Facility any Lender or any Affiliate or Approved Fund of any Lender (none of whom shall constitute a Defaulting Lender) or any other Person acceptable (which acceptance shall not be unreasonably withheld
or delayed) to the Applicable Administrative Agent (in each case, a “Substitute Lender”). 
 (b) Procedure. To
substitute such Affected Lender or pay in full the Obligations owed to such Affected Lender under such Facility, the Borrower shall deliver a notice to the Applicable Administrative Agent and such Affected Lender. The effectiveness of such payment
or substitution shall be subject to the delivery to the Applicable Administrative Agent by the Borrower (or, as may be applicable in the case of a substitution, by the Substitute Lender) of (i) payment for the account of such Affected Lender
of, to the extent accrued through, and outstanding on, the effective date for such payment or substitution, all Obligations (including, to the extent applicable, pursuant to Section 2.11(c)) owing to such Affected Lender with respect to
such Facility (including those that will be owed because of such payment and all Obligations that would be owed to such Lender if it was solely a Lender in such Facility), (ii) in the case of a payment in full of the Obligations owing to such
Affected Lender in the Revolving Credit Facility, payment of any amount that, after giving effect to the termination of the Commitment of such Affected Lender, is required to be paid pursuant to Section 2.8(d) and (iii) in the case
of a substitution, (A) payment of the assignment fee set forth in Section 11.2(c) and (B) an assumption agreement in form and substance satisfactory to the Applicable Administrative Agent whereby the Substitute Lender shall,
among other things, agree to be bound by the terms of the Loan Documents and assume the relevant Revolving Credit Commitment of the Affected Lender under such Facility. 

(c) Effectiveness. Upon satisfaction of the conditions set forth in clause (b) above, the Applicable Administrative Agent
shall record such substitution or payment in the 

  
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applicable Register, whereupon (i) in the case of any payment in full in any Facility, such Affected Lender’s Commitments in such Facility shall be terminated and (ii) in the case
of any substitution in any Facility, (A) the Affected Lender shall sell and be relieved of, and the Substitute Lender shall purchase and assume, all rights and claims of such Affected Lender under the Loan Documents with respect to such
Facility, except that the Affected Lender shall retain such rights expressly providing that they survive the repayment of the Obligations and the termination of the Commitments, (B) the Substitute Lender shall become a “Lender”
hereunder having a Commitment in such Facility in the amount of such Affected Lender’s Commitment in such Facility and (C) the Affected Lender shall execute and deliver to the Applicable Administrative Agent an Assignment to evidence such
substitution and deliver any Note in its possession with respect to such Facility; provided, however, that the failure of any Affected Lender to execute any such Assignment or deliver any such Note shall not render such sale and
purchase (or the corresponding assignment) invalid. 
 Section 2.19 Incremental Term Loans and Incremental Revolving Credit
Commitments. 
 (a) The Borrower may, at any time after the Closing Date, at the Borrower’s written request to the Applicable
Administrative Agent, request that one or more Lenders and/or other financial institutions that will become Lenders hereunder (x) make incremental term loans hereunder either through adding such incremental term loans to the outstanding
principal amount of the B Term Loans hereunder or any Tranche of Incremental Term Loans then outstanding or through a separate Tranche of Term Loans hereunder (such incremental term loans, in either case, “Incremental Term Loans”
and the commitments to which such Incremental Term Loans relate, the “Incremental Term Loan Commitments”) and/or (y) increase the aggregate amount of the Revolving Credit Commitments through adding incremental revolving credit
commitments to the then outstanding amount of Revolving Credit Commitments hereunder (such revolving credit commitments, “Incremental Revolving Credit Commitments”); provided that: 

(i) (x) the aggregate principal amount of any requested Incremental Term Loans shall be in a minimum amount of $5,000,000 and
in integral multiples of $1,000,000 in excess thereof and (y) the aggregate amount of any requested Incremental Revolving Credit Commitments shall be in a minimum amount of $5,000,000 and in integral multiples of $1,000,000 in excess thereof;

 (ii) the Loan Parties shall execute and deliver such agreements, instruments, documents, resolutions, opinions of counsel,
solvency certificate and officer’s certificates and take such other actions as may be reasonably requested by the Applicable Administrative Agent in connection with such Incremental Term Loan Commitments and/or Incremental Revolving Credit
Commitments; 
 (iii) subject to the last paragraph of this Section 2.19(a), no Default or Event of Default shall
have occurred and be continuing or would occur after giving effect to the incurrence of (x) the respective Incremental Term Loans pursuant to such Incremental Term Loan Commitments and the application of proceeds therefrom and/or (y) the
respective Incremental Revolving Credit Commitments or any Revolving Loans to be made in connection therewith and the application of proceeds therefrom; 

(iv) subject to the last paragraph of this Section 2.19(a), all of the representations and warranties contained
herein and in the other Loan Documents are true 

  
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and correct in all material respects (it being understood that (x) any representation or warranty that is qualified by materiality or Material Adverse Effect shall be required to be true and
correct in all respects and (y) any representation or warranty which by its terms is made as of a specified date shall be required to be true and correct in all material respects (or all respects, as the case may be) as of such specified date);

 (v) the Borrower shall be in compliance, on a Pro Forma Basis (and assuming the full utilization of the respective
Incremental Term Loan Commitments and/or Incremental Revolving Credit Commitments), as of the last day of the most recently ended Fiscal Quarter on or prior to the date of the respective incurrence for which Financial Statements have been delivered
hereunder, as if such Incremental Term Loans and/or Incremental Revolving Credit Commitments had been incurred (and, if incurred to finance a Permitted Acquisition, as if such Permitted Acquisition had been consummated) on the first day of the four
Fiscal Quarter period ended on the last day of such most recently ended Fiscal Quarter (and after giving effect to any other Pro Forma Transaction that is consummated after the beginning of the most recently ended Fiscal Quarter but prior to or
simultaneously with the borrowing of such Incremental Term Loans and/or the incurrence of such Incremental Revolving Credit Commitments), with (x) a Consolidated Secured Leverage Ratio of no greater than 4.00:1.00 and (y) a Consolidated
Total Leverage Ratio of no greater than 5.75:1.00; 
 (vi) (A) in the case of Incremental Revolving Credit Commitments
incurred pursuant to this Section 2.19, the terms and conditions of such Incremental Revolving Credit Commitments (and any Revolving Loans to be made pursuant thereto, including as to maturity and pricing (including interest rate,
interest rate margins, rate floors (if any) and unused fees, but excluding underwriting fees, arrangement fees, upfront fees and other similar fees) shall be the same as the Revolving Credit Commitments and (B) in the case of Incremental Term
Loans made under this Section 2.19, such Incremental Term Loans shall have an Incremental Term Loan Maturity Date no earlier than the Scheduled B Term Loan Maturity Date and shall have a Weighted Average Life to Maturity no shorter than
the then remaining Weighted Average Life to Maturity of the B Term Loans; provided, however, if the new Incremental Term Loans to be made pursuant this Section 2.19 are, at the Borrower’s election, to be added to the
aggregate outstanding principal amount of the B Term Loans or any then outstanding Tranche of Incremental Term Loans, such Incremental Term Loans shall have the same Maturity Date as the B Term Loans or such Tranche of Incremental Term Loans, as the
case may be, and shall have the same scheduled amortization dates as the B Term Loans or such Tranche of Incremental Term Loans, as the case may be, pursuant to Section 2.6(c) or the respective Incremental Amendment, and with the amount
of each scheduled amortization payment applicable to such new Incremental Term Loans to be the same (on a proportionate basis) as was previously applicable to the remaining scheduled amortization payments of the B Term Loans or such Tranche or
Incremental Term Loans, as the case may be, thereby increasing the amount of each then remaining scheduled amortization payment of the B Term Loans or such Tranche of Incremental Term Loans, as the case may be, pursuant to Section 2.6(c)
or the respective Incremental Amendment proportionately; 
 (vii) if the Effective Yield for any new Tranche of Incremental
Term Loans made under this Section 2.19 determined as of the initial funding date for such 

  
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Tranche of Incremental Term Loans exceeds the Effective Yield relating to the B Term Loans immediately prior to the making of such Tranche of Incremental Term Loans by more than 0.50%, then the
Effective Yield relating to the B Term Loans shall be adjusted to be equal to the Effective Yield relating to such Tranche of Incremental Term Loans minus 0.50%; 

(viii) in the case of any Incremental Term Loans that are to be made pursuant to (and to constitute a part of) the B Term Loans
or any then outstanding Tranche of Incremental Term Loans, (I) such new Incremental Term Loans shall have the same Applicable Margins as the Tranche of Term Loans to which such Incremental Term Loans shall be added; provided that, if the
Applicable Margins for such new Incremental Term Loans are greater than the Applicable Margins for the Tranche of Term Loans to which such new Incremental Term Loans shall be added, the Applicable Margins for such Tranche of Term Loans shall be
increased by an amount necessary to eliminate such deficiency, and (II) subject to preceding clause (I), the Effective Yield applicable to such new Incremental Term Loans shall be determined by the Borrower and the Lenders providing such Incremental
Term Loans; provided that, in the case of any Incremental Term Loans that are to be added to (and constitute a part of) the B Term Loans, if the Effective Yield of such new Incremental Term Loans exceeds the Effective Yield for the B Term
Loans, then the Effective Yield for the B Term Loans shall be increased (to the extent necessary) such that the Effective Yield thereof is not less than the Effective Yield of such new Incremental Term Loans minus 0.50%; 

(ix) except as expressly set forth above, prior to the date on which all B Term Loans have been repaid in full, all other terms
and conditions with respect to any Incremental Term Loans made pursuant to this Section 2.19 shall be the same as the terms and conditions applying to the B Term Loans, provided that any Tranche of Incremental Term Loans may
provide that different terms and conditions apply after such date; 
 (x) the Borrower shall have demonstrated to the
Applicable Administrative Agent’s reasonable satisfaction that the full amount of the Incremental Term Loans and/or Incremental Revolving Credit Commitments (assuming the full utilization thereof) to be incurred may be incurred without
violating the terms of any other material Indebtedness of the Borrower or any of its Subsidiaries or the documentation governing any such Indebtedness (excluding any such Indebtedness that is to be refinanced in whole with the proceeds of such
Incremental Term Loan Commitments and/or Incremental Revolving Credit Commitments in compliance with this Agreement and the other Loan Documents); and 

(xi) the Borrower shall have delivered to the Applicable Administrative Agent a certificate executed by a Responsible Officer
of the Borrower, (A) certifying compliance with the requirements of (x) in the case of Incremental Term Loans, preceding clauses (i) through (x), inclusive, and (y) in the case of Incremental Revolving Credit
Commitments, preceding clauses (i) through (vi), inclusive, and (x) and (B) containing the calculations (in reasonable detail) required by (x) in the case of Incremental Term Loans, the preceding clauses
(v), (vi), (vii), (viii) and, if applicable, (x) and (y) in the case of Incremental Revolving Credit Commitments, the preceding clauses (v), (vi) and, if applicable, (x). 

  
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 Any request under this Section 2.19 shall be submitted by the Borrower in writing to the Applicable
Administrative Agent (which shall promptly forward copies to the Lenders for which it is acting as an Administrative Agent). The Borrower may also specify any fees offered to those Lenders and other financial institutions that will become Lenders
hereunder (the “Increasing Lenders”) that agree to provide Incremental Term Loan Commitments and/or Incremental Revolving Credit Commitments (which fees, as it relates to any Lender or other financial institution that will become a
Lender, may be variable based upon the amount of Incremental Term Loan Commitments and/or Incremental Revolving Credit Commitments that any such Lender or other financial institution is willing to provide). No Lender shall have any obligation,
express or implied, to provide Incremental Term Loan Commitments and/or Incremental Revolving Credit Commitments. Only the consent of each Increasing Lender shall be required pursuant to this Section 2.19 in connection with the provision
or implementation of any Incremental Term Loan Commitments or incurrence of Incremental Term Loans thereunder or any Incremental Revolving Credit Commitments. No Lender which declines to provide Incremental Term Loan Commitments or Incremental
Revolving Credit Commitments may be replaced with respect to its existing Term Loans or Revolving Credit Commitments as a result thereof without such Lender’s consent. 

Notwithstanding anything to the contrary contained in this Section 2.19(a), to the extent that the proceeds of any Incremental Term Loans are,
substantially concurrently with the receipt thereof, to be used by the Borrower or any other Group Member to finance, in whole or in part, a Limited Condition Acquisition, then (x) the requirement set forth in clause (a)(iv) above that
all representations and warranties be true and correct in all material respects (other than certain customary “specified representations” as may be agreed by the relevant Lenders providing such Incremental Term Loans and the Borrower)
and/or (y) the absence of a Default or Event of Default requirement set forth in clause (a)(iii) above (other than with respect to any Event of Default under Sections 9.1(a) and (e)), in each case, may be waived or limited,
as agreed between the Borrower and the Lenders providing such Incremental Term Loans without the consent of the existing Lenders 
 (b) Each
Increasing Lender shall as soon as reasonably practicable specify in writing the amount of the proposed Incremental Term Loan Commitments or Incremental Revolving Credit Commitments, as applicable, that it is willing to provide (provided that
any Lender not so responding within 5 Business Days (or such shorter period as may be specified by the Applicable Administrative Agent) shall be deemed to have declined such a request). The Borrower may accept some or all of the offered amounts or
designate new lenders that are reasonably acceptable to the Applicable Administrative Agent as additional Lenders hereunder in accordance with this Section 2.19 (but only to the extent that such new lender would otherwise be eligible to
be a Lender hereunder pursuant to Section 11.2(b), including by reason of obtaining all necessary consents thereunder in accordance with the terms thereof) (each such new lender being a “New Lender”), which New Lenders
may provide all or a portion of the aggregate principal amount of the applicable Incremental Term Loan Commitments and/or Incremental Revolving Credit Commitments, as applicable. 

(c) Subject to the foregoing, any increase requested by the Borrower shall be effective upon (A) delivery to the Applicable
Administrative Agent of each of the following documents: (i) a notice of such increase to the Increasing Lenders and New Lenders, in form and substance reasonably acceptable to the Applicable Administrative Agent, signed by a Responsible
Officer of the Borrower; (ii) to the extent requested by any New Lender or Increasing Lender, 

  
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executed Notes in respect of Incremental Term Loan Commitments or Incremental Revolving Credit Commitments issued by the Borrower in accordance with Section 2.14(e); (iii) an
amendment (an “Incremental Amendment”) to this Agreement and, as appropriate, the other Loan Documents, executed by the Borrower, each other applicable Loan Party, each Increasing Lender (if any), each New Lender (if any), the
Applicable Administrative Agent and the Collateral Agent, to the extent necessary or appropriate in the reasonable opinion of the Applicable Administrative Agent to give effect to any Incremental Term Loans and/or Incremental Revolving Credit
Commitments, in each case, to be made or incurred pursuant to this Section 2.19 in each case on terms consistent with this Section 2.19; and (iv) any other certificates or documents that the Applicable Administrative
Agent shall reasonably request, in form and substance reasonably satisfactory to the Applicable Administrative Agent, and (B) satisfaction on the effective date of any Incremental Amendment and the making of each Incremental Term Loan
Commitments and/or Incremental Revolving Credit Commitments of (x) subject to the provisions of the last paragraph of Section 2.19(a), each of the applicable conditions specified in Section 3.2, and (y) such other
conditions (if any) as the parties thereto shall mutually agree as set forth in the respective Incremental Amendment. Notwithstanding anything to the contrary in Section 11.1, the Applicable Administrative Agent and the Collateral Agent
are expressly permitted, without the consent of the other Lenders, to enter into an Incremental Amendment. 
 (d) On each effective date
with respect to any Incremental Revolving Credit Commitments pursuant to this Section 2.19, (i) the Revolving Credit Commitments shall be increased by an amount equal to the respective Incremental Revolving Credit Commitments (and
the Revolving Credit Commitment of each Revolving Credit Commitment Increasing Lender shall constitute a part of, and be added to, the Revolving Credit Commitment of such Lender and the aggregate Revolving Credit Commitments), (ii) each Lender
in respect of the Revolving Credit Facility immediately prior to such increase will automatically and without further act be deemed to have assigned to each Increasing Lender and/or New Lender, as applicable, providing a portion of the increase to
the Revolving Credit Commitments under the Revolving Credit Facility (each, a “Revolving Credit Commitment Increase Lender”), and each such Revolving Credit Commitment Increase Lender will automatically and without further act be
deemed to have assumed, a portion of such Lender’s participations hereunder in outstanding L/C Exposure under the Revolving Credit Facility and Swing Loans such that, after giving effect to each such deemed assignment and assumption of
participations, the percentage of the aggregate outstanding (x) participations hereunder in L/C Exposure and (y) participations hereunder in Swing Loans held by each Lender (including each such Revolving Credit Commitment Increase Lender)
under the Revolving Credit Facility will equal the percentage of the aggregate Revolving Credit Commitments in respect of the Revolving Credit Facility of all Lenders represented by such Lender’s Revolving Credit Commitment in respect of the
Revolving Credit Facility and (iii) if, on the date of such increase, there are any Revolving Loans outstanding, such Revolving Loans shall on or prior to the effective date of such increase be prepaid from the proceeds of Revolving Loans under
the Revolving Credit Facility made hereunder (reflecting such increase in Revolving Credit Commitments), which prepayment shall be accompanied by accrued interest on the Revolving Loans being prepaid and any costs incurred by any Lender in
accordance with Section 2.16. The Administrative Agents and the Lenders hereby agree that the minimum borrowing, pro rata borrowing and pro rata payment requirements contained elsewhere in this Agreement shall not apply to the
transactions effected pursuant to the immediately preceding sentence. 

  
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 Section 2.20 Defaulting Lenders. Notwithstanding any provision of this Agreement to
the contrary, if any Lender becomes a Defaulting Lender, then the following provisions shall apply for so long as such Lender is a Defaulting Lender: 

(a) if any Swing Loan Exposure or L/C Exposure exists at the time a Revolving Credit Lender becomes a Defaulting Lender then: 

(i) all or any part of such Swing Loan Exposure and L/C Exposure shall be reallocated among the Revolving Credit Lenders that
are Non-Defaulting Lenders in accordance with their respective Revolving Credit Percentages (calculated without regard to such Defaulting Lender’s Revolving Credit Commitment) but only to the extent (x) the sum of the Individual Exposures
of all Revolving Credit Lenders that are Non-Defaulting Lenders plus such Defaulting Lender’s Swing Loan Exposure and L/C Exposure does not exceed the aggregate amount of the Revolving Credit Commitments of all Revolving Credit Lenders that are
Non-Defaulting Lenders, (y) immediately following the reallocation to a Revolving Credit Lender that is a Non-Defaulting Lender, the Individual Exposure of such Revolving Credit Lender does not exceed its Revolving Credit Commitment at such
time and (z) the conditions set forth in Section 3.2 are satisfied at such time (it being understood that no reallocation hereunder shall constitute a waiver or release of any claim of any party hereunder against a Defaulting Lender
arising from that Lender having become a Defaulting Lender, including any claim of a Lender that is a Non-Defaulting Lender as a result of such Lender’s increased exposure following such reallocation); 

(ii) if the reallocation described in clause (i) above cannot, or can only partially, be effected, the Borrower shall
promptly, but in any event within two Business Days following notice by the Applicable Administrative Agent, (x) first, prepay the Swingline Lender’s Fronting Exposure and (y) second, cash collateralize in a manner
reasonably satisfactory to the applicable L/C Issuer such L/C Issuer’s Fronting Exposure (after giving effect to any partial reallocation pursuant to clause (i) above) in aggregate amount equal to 105% of such L/C Issuer’s Fronting
Exposure for so long as such Fronting Exposure is outstanding (the “L/C Back-Stop Arrangements”); 
 (iii)
the Borrower shall not be required to pay any fees to such Defaulting Lender pursuant to Section 2.11(b) with respect to such Defaulting Lender’s L/C Exposure other than for the period for which such Defaulting Lender has provided
cash collateral in a manner reasonably satisfactory to the applicable L/C Issuer in an aggregate amount equal to 105% of such Defaulting Lender’s L/C Exposure; 

(iv) if the L/C Exposure of the Non-Defaulting Lenders is reallocated pursuant to this Section 2.20(a), then
(subject to clause (iii) above) the fees payable to the Revolving Credit Lenders that are Non-Defaulting Lenders pursuant to Section 2.11(b) shall be adjusted in accordance with such Revolving Credit Lenders’ Revolving
Credit Percentages; and 
 (v) if any Defaulting Lender’s L/C Exposure is neither cash collateralized nor reallocated
pursuant to this Section 2.20(a), then, without prejudice to any rights or remedies of any L/C Issuer or any Revolving Credit Lender hereunder, all Letter of Credit fees payable under Section 2.11(b) with respect to such
Defaulting Lender’s L/C Exposure shall be payable to each respective L/C Issuer until such L/C Exposure is cash collateralized and/or reallocated; 

  
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 (b) in the case of a Lender Default with respect to a Revolving Credit Lender, the Borrower shall
not be required to pay any fees to any such Revolving Credit Lender that is a Defaulting Lender as provided in Section 2.11(a) with respect to such Defaulting Lender’s unused Revolving Credit Commitments; 

(c) notwithstanding anything to the contrary contained in Section 2.3 or Section 2.4, so long as any Revolving Credit
Lender is a Defaulting Lender, (i) the Swingline Lender shall not be required to fund any Swing Loan and no L/C Issuer shall be required to issue, amend, renew or increase any Letter of Credit, unless it is satisfied that it will have no
Fronting Exposure after giving effect to such Swing Loan or such issuance, renewal or increase of such Letter of Credit, and (ii) participating interests in any such newly issued or increased Letter of Credit or newly made Swing Loan shall be
allocated among Revolving Credit Lenders that are Non-Defaulting Lenders in a manner consistent with Section 2.20(a)(i) (and Defaulting Lenders shall not participate therein); 

(d) in the event that the Pro Rata Administrative Agent, the Borrower, each L/C Issuer and the Swingline Lender each agree that a Defaulting
Lender has adequately remedied all matters that caused such Revolving Credit Lender to be a Defaulting Lender, then (i) such Revolving Credit Lender shall again be entitled (commencing as of the time of such determination) to any fees payable
to it as a Non-Defaulting Lender pursuant to Section 2.11(a) with respect to its unused Revolving Credit Commitments and pursuant to Section 2.11(b) with respect to outstanding Letters of Credit, (ii) the Swing Loan
Exposure and L/C Exposure of the Revolving Credit Lenders shall be readjusted to reflect the inclusion of such Revolving Credit Lender’s Revolving Credit Commitments and on such date such Revolving Credit Lender shall purchase at par such of
the Revolving Loans of the other Revolving Credit Lenders (other than Swing Loans) as the Pro Rata Administrative Agent shall determine may be necessary in order for such Revolving Credit Lender to hold such Revolving Loans in accordance with its
Revolving Credit Percentage and (iii) so long as no Event of Default then exists, all funds held as cash collateral pursuant to the L/C Back-Stop Arrangements shall thereafter be promptly returned to the Borrower. If the Revolving Credit
Commitments have been terminated, all other Revolving Credit Obligations have been paid in full and no Letters of Credit are outstanding, then, so long as no Event of Default then exists, all funds held as cash collateral pursuant to the L/C
Back-Stop Arrangements shall thereafter be promptly returned to the Borrower; and 
 (e) any payment of principal, interest, fees or other
amounts received by the Applicable Administrative Agent for the account of a Defaulting Lender (whether voluntary or mandatory, at maturity, pursuant to Article IX or otherwise) or received by the Applicable Administrative Agent from a Defaulting
Lender pursuant to Section 11.8 shall be applied at such time or times as may be determined by the Applicable Administrative Agent as follows: first, to the payment of any amounts owing by such Defaulting Lender to the
Administrative Agents hereunder; second, to the payment on a pro rata basis of any amounts owing by such Defaulting Lender to any L/C Issuer or the Swingline Lender hereunder; third, to cash collateralize the L/C
Issuers’ Fronting Exposure with respect to such Defaulting Lender in a manner reasonably satisfactory to the applicable L/C Issuer; fourth, as the Borrower may request (so long as no Default or Event of Default exists), to the funding of
any Loan in respect of which such Defaulting Lender has failed to fund its portion thereof as required by this Agreement, as determined by the Applicable Administrative Agent; fifth, if so determined by the Applicable

  
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Administrative Agent and the Borrower, to be held in a deposit account and released pro rata in order to (x) satisfy such Defaulting Lender’s potential future funding obligations with
respect to Loans under this Agreement and (y) cash collateralize the L/C Issuers’ future Fronting Exposure with respect to such Defaulting Lender with respect to future Letters of Credit issued under this Agreement, in a manner reasonably
satisfactory to the applicable L/C Issuer; sixth, to the payment of any amounts owing to the Lenders, the L/C Issuers or the Swingline Lender as a result of any judgment of a court of competent jurisdiction obtained by any Lender, the L/C
Issuers or the Swingline Lender against such Defaulting Lender as a result of such Defaulting Lender’s breach of its obligations under this Agreement; seventh, so long as no Default or Event of Default exists, to the payment of any
amounts owing to the Borrower as a result of any judgment of a court of competent jurisdiction obtained by the Borrower against such Defaulting Lender as a result of such Defaulting Lender’s breach of its obligations under this Agreement; and
eighth, to such Defaulting Lender or as otherwise directed by a court of competent jurisdiction; provided that if (x) such payment is a payment of the principal amount of any Loans or L/C Obligations in respect of which such
Defaulting Lender has not fully funded its appropriate share, and (y) such Loans were made or the related Letters of Credit were issued at a time when the conditions set forth in Section 3.2 were satisfied or waived, such payment shall be
applied solely to pay the Loans of, and L/C Obligations owed to, all Lenders who are not Defaulting Lenders on a pro rata basis prior to being applied to the payment of any Loans of, or L/C Obligations owed to, such Defaulting Lender
until such time as all Loans and funded and unfunded participations in L/C Obligations and Swing Loans are held by the Lenders pro rata in accordance with the such Lender’s Revolving Credit Commitments. Any payments, prepayments or other
amounts paid or payable to a Defaulting Lender that are applied (or held) to pay amounts owed by a Defaulting Lender or to post cash collateral pursuant to this Section 2.20(e) shall be deemed paid to and redirected by such Defaulting Lender,
and each Lender irrevocably consents hereto 
 Section 2.21 Reverse Dutch Auction Repurchases. (a) The Borrower may
from time to time, at its discretion, conduct modified reverse Dutch auctions in order to purchase Term Loans (each, an “Auction”), and with each such Auction to be managed exclusively by an investment bank of recognized standing
selected by the Borrower (in such capacity, the “Auction Manager”), so long as the following conditions are satisfied: 

(i) each Auction shall be conducted in accordance with the procedures, terms and conditions set forth in this
Section 2.21 and on Schedule 2.21; 
 (ii) no Default or Event of Default shall have occurred and be
continuing on the date of the delivery of each Auction Notice and at the time of purchase of any Term Loans in connection with any Auction; 

(iii) each Auction shall be open and offered to all Lenders of the relevant Tranche of Term Loans on a pro rata
basis; 
 (iv) the minimum principal amount (calculated on the face amount thereof) of Term Loans that the Borrower shall
offer to purchase in any such Auction shall be no less than $25,000,000 (unless another amount is agreed to by the Applicable Administrative Agent); 

(v) the aggregate principal amount (calculated on the face amount thereof) of all Term Loans purchased by the Borrower pursuant
to an Auction shall automatically be canceled and retired by the Borrower on the settlement date of the relevant purchase (and may not be resold); 

  
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 (vi) no proceeds of Revolving Loans or Swing Loans may be used to consummate an
Auction; 
 (vii) no more than one Auction may be ongoing at any one time; and 

(viii) at the time of each purchase of Term Loans through an Auction, the Borrower shall have delivered to the Auction Manager
and the Applicable Administrative Agent an officer’s certificate of a Responsible Officer of the Borrower certifying as to compliance with preceding clauses (ii) and (vi)). 

(b) The Borrower must terminate an Auction if it fails to satisfy one or more of the conditions set forth above which are required to be met
at the time which otherwise would have been the time of purchase of Term Loans pursuant to the respective Auction. The Borrower shall have no liability to any Lender for any termination of the respective Auction as a result of its failure to satisfy
one or more of the conditions set forth above which are required to be met at the time which otherwise would have been the time of purchase of Term Loans pursuant to the respective Auction, and any such failure shall not result in any Default or
Event of Default hereunder. With respect to all purchases of Term Loans made by the Borrower pursuant to this Section 2.21, (x) the Borrower shall pay on the settlement date of each such purchase all accrued and unpaid interest
(except to the extent otherwise set forth in the relevant offering documents), if any, on the purchased Term Loans up to the settlement date of such purchase and (y) such purchases (and the payments made by the Borrower and the cancellation of
the purchased Term Loans, in each case in connection therewith) shall not constitute voluntary or mandatory payments or prepayments for purposes of Sections 2.7 and 2.8 (other than to the extent set forth in Section 2.8(a))
and Section 11.9 (although the par principal amount of Term Loans of the respective Tranche so purchased pursuant to this Section 2.21 shall be applied to reduce the remaining scheduled installments of such Tranche of Term
Loans pursuant to Section 2.6(b) and (c) of the applicable Lenders being repaid on a pro rata basis (based on the remaining principal amount thereof) without affecting the scheduled installments of such Tranche
of Term Loans relating to the Lenders whose Term Loans have not been so purchased). 
 (c) The Administrative Agents and the Lenders hereby
consent to the Auctions and the other transactions contemplated by this Section 2.21 (provided that no Lender shall have an obligation to participate in any such Auctions) and hereby waive the requirements of any provision of this
Agreement (including, without limitation, Sections 2.7 and 2.8 and Section 11.9 (it being understood and acknowledged that purchases of the Term Loans by the Borrower contemplated by this Section 2.21 shall not
constitute Investments by the Borrower)) or any other Loan Document that may otherwise prohibit any Auction or any other transaction contemplated by this Section 2.21. The Auction Manager acting in its capacity as such hereunder shall be
entitled to the benefits of the provisions of Article X and Sections 11.3 and 11.4 mutatis mutandis as if each reference therein to the “Administrative Agent” were a reference to the Auction Manager, and
the Administrative Agents shall cooperate with the Auction Manager as reasonably requested by the Auction Manager in order to enable it to perform its responsibilities and duties in connection with each Auction. 

(d) Each Lender participating in any Auction hereby acknowledges and agrees that in connection with such Auction (1) the Borrower may
have, and later may come into 

  
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possession of, information regarding the Loans or the Loan Parties hereunder that is not known to such Lender and that may be material to a decision by such Lender to participate in such Auction
(such information, the “Excluded Information”), (2) such Lender has independently, without reliance on the Borrower, any of its Subsidiaries, the Administrative Agents, any Joint Lead Arranger or any of their respective
Affiliates, made its own analysis and determination to participate in such Auction notwithstanding such Lender’s lack of knowledge of the Excluded Information and (3) none of the Borrower, any of its Subsidiaries, any Administrative Agent,
any Joint Lead Arranger or any of their respective Affiliates shall have any liability to such Lender, and such Lender hereby waives and releases, to the extent permitted by law, any claims such Lender may have against the Borrower, any of its
Subsidiaries, any Administrative Agent, any Joint Lead Arranger and their respective Affiliates, under applicable law or otherwise, with respect to the nondisclosure of the Excluded Information. Each Lender participating in any Auction further
acknowledges that the Excluded Information may not be available to the Administrative Agents, the Joint Lead Arrangers or the other Lenders. 

Section 2.22 Specified Refinancing Loans. (a) The Borrower may, from time to time after the Closing Date, and subject to
the consent of the Applicable Administrative Agent (which consent shall not be unreasonably withheld, delayed or conditioned), add one or more new term loan facilities (“Specified Refinancing Term Loans”) or new revolving credit
facilities (“Specified Refinancing Revolving Credit Commitments”) under this Agreement pursuant to procedures reasonably specified by the Applicable Administrative Agent and reasonably acceptable to the Borrower, to refinance all or
any portion of any Tranche of Term Loans or Revolving Credit Commitments (and related outstandings), as applicable, then outstanding under this Agreement (subject to clause (A) of the proviso at the end of this sentence), in each
case pursuant to a Refinancing Amendment; provided that any such Specified Refinancing Term Loans and Specified Refinancing Revolving Credit Commitments: 

(i) will rank pari passu in right of payment as the other Term Loans or Revolving Credit Commitments, as
applicable, hereunder; 
 (ii) will be incurred by the Borrower and will not be guaranteed by any Person that is not a
Guarantor; 
 (iii) will be, if secured, (1) secured solely by the Collateral on a pari passu or junior
basis with the Liens securing the Obligations and (2) subject to intercreditor arrangements reasonably satisfactory to the Administrative Agents; 

(iv) will have such pricing and optional prepayment terms as may be agreed by the Borrower and the applicable Lenders thereof;

 (v) will have a maturity date that is not prior to the Maturity Date of the Term Loans or the Revolving Credit
Commitments, as applicable, being refinanced and (x) in the case of any Specified Refinancing Revolving Credit Commitments, shall not have any mandatory commitment reductions or amortization that is prior to the scheduled Maturity Date of the
Revolving Credit Commitments being refinanced and (y) in the case of any Specified Refinancing Term Loans, will have a Weighted Average Life to Maturity that is not shorter than the Weighted Average Life to Maturity then in effect of the Term
Loans being refinanced; 

  
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 (vi) will share ratably (or if unsecured or junior as to security, on a junior
basis in respect of) any optional and mandatory prepayments of Term Loans or Revolving Loans, as applicable (unless the Lenders providing such Specified Refinancing Term Loans or Specified Refinancing Revolving Credit Commitments, as applicable,
agree to participate on a less than pro rata basis in any such optional or mandatory prepayments); 
 (vii) in
the case of any Specified Refinancing Revolving Credit Commitments, shall provide that the borrowing of Revolving Loans with respect to Specified Refinancing Revolving Credit Commitments shall be made on a pro rata basis (or, in the
case of any Tranche of Specified Revolving Credit Commitments that are unsecured or secured on a junior basis, on a less than pro rata basis) with all other Revolving Credit Commitments then existing on the date on which the Specified
Refinancing Revolving Credit Facility is incurred; 
 (viii) in the case of any Specified Refinancing Revolving Credit
Commitments that include Letters of Credit and Swing Loans under the applicable Refinancing Amendment which mature or expire after a Maturity Date when there exist Specified Refinancing Revolving Credit Commitments with a later Maturity Date, all
Swing Loans and Letters of Credit shall be participated on a pro rata basis by all Revolving Credit Lenders with Revolving Credit Commitments in accordance with their percentage of the Revolving Credit Commitments (without giving
effect to changes thereto on an earlier Maturity Date with respect to Letters of Credit theretofore incurred or issued, although the respective Refinancing Amendment may contain technical changes related to the borrowing, replacement Letter of
Credit and Swing Loan procedures of the Revolving Credit Commitments in respect of which the Specified Refinancing Revolving Credit Commitments were incurred); and 

(ix) subject to clauses (iv), (v) and (vii) above, will have terms and conditions (other than
pricing and optional prepayment and redemption terms) that are substantially identical to, or less favorable, when taken as a whole, to the Lenders providing such Specified Refinancing Term Loans or Specified Refinancing Revolving Credit
Commitments, as applicable, than, the terms and conditions of the Term Loans or Revolving Credit Commitments being refinanced (provided that a certificate of a Responsible Officer of the Borrower delivered to the Applicable Administrative
Agent in good faith at least five Business Days prior to the incurrence of such Specified Refinancing Term Loans or Specified Refinancing Revolving Credit Commitments, as applicable, together with a reasonably detailed description of the material
terms and conditions of such Specified Refinancing Term Loans or drafts of the documentation relating thereto, stating that the Borrower has determined in good faith that such terms and conditions satisfy the requirements set forth in this clause
(vii) shall be conclusive evidence that such terms and conditions satisfy such requirement unless the Applicable Administrative Agent provides notice to the Borrower of an objection (including a reasonable description of the basis upon
which it objects) within five Business Days after being notified of such determination by the Borrower). 
 (b) (x) The Net Cash Proceeds of
any Specified Refinancing Term Loans shall be applied, substantially concurrently with the incurrence thereof, to the pro rata prepayment of outstanding Term Loans being so refinanced, in each case pursuant to Section 2.8(b)(ii) and
(y) upon the incurrence of any Specified Refinancing Revolving 

  
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Credit Commitments, the Revolving Credit Commitments being refinanced shall be permanently reduced as, and to the extent, provided in Section 2.5(b)(vi) (together with any applicable
prepayment of outstanding Revolving Loans thereunder to the extent that such outstandings exceed the remaining Revolving Credit Commitments being refinanced); provided, however, that (A) the Net Cash Proceeds from any incurrence
of Specified Refinancing Term Loans may not be used to prepay any Tranche of outstanding Term Loans that are either unsecured or secured on a junior basis to the Obligations at a time when more senior Term Loans are outstanding (or will remain
outstanding after giving effect to any such prepayment), (B) Specified Refinancing Revolving Credit Commitments may not be used to refinance any Tranche of Revolving Credit Commitments that are either unsecured or secured on a junior basis to
other Tranches of Revolving Credit Commitments at a time when more senior Revolving Credit Commitments are outstanding (or will remain outstanding after giving effect to any such refinancing) and (C) such Specified Refinancing Term Loans or
Specified Refinancing Revolving Credit Commitments, as applicable, (x) may provide for any additional or different financial or other covenants or other provisions that are agreed among the Borrower and the Lenders thereof and applicable only
during periods after the Latest Maturity Date then in effect and (y) shall not have a principal amount (or accreted value) greater than the Term Loans being refinanced (plus all accrued and unpaid interest thereon, and all fees, discounts,
premiums or expenses incurred in connection therewith) or the Revolving Credit Commitments being refinanced, as applicable. 
 (c) The
Borrower shall make any request for Specified Refinancing Term Loans or Specified Refinancing Revolving Credit Commitments, as applicable, pursuant to a written notice to the Applicable Administrative Agent specifying in reasonable detail the
proposed terms thereof. Any proposed Specified Refinancing Term Loans or Specified Refinancing Revolving Credit Commitments, as applicable, shall first be requested on a ratable basis from existing Lenders in respect of the Term Loans or Revolving
Credit Commitments being refinanced. At the time of sending such notice to such Lenders, the Borrower (in consultation with the Applicable Administrative Agent) shall specify the time period within which each applicable Lender is requested to
respond (which shall in no event be less than 5 Business Days from the date of delivery of such notice or such shorter period as may be agreed by the Applicable Administrative Agent in its sole discretion). Each applicable Lender shall notify the
Applicable Administrative Agent within such time period whether or not it agrees to participate in providing such Specified Refinancing Term Loans or Specified Refinancing Revolving Credit Commitments, as applicable, and, if so, whether by an amount
equal to, greater than, or less than its ratable portion (based on such Lender’s ratable share in respect of the applicable Term Loans or Revolving Credit Commitments) of such Specified Refinancing Term Loans or Specified Refinancing Revolving
Credit Commitments. Any Lender approached to provide all or a portion of any Specified Refinancing Term Loans or Specified Refinancing Revolving Credit Commitments may elect or decline, in its sole discretion, to provide such Specified Refinancing
Term Loans or Specified Refinancing Revolving Credit Commitments, as applicable. Any Lender not responding within such time period shall be deemed to have declined to participate in providing such Specified Refinancing Term Loans or Specified
Refinancing Revolving Credit Commitments. The Applicable Administrative Agent shall notify the Borrower and each applicable Lender of the Lenders’ responses to each request made hereunder. To achieve the full amount of a requested issuance of
Specified Refinancing Term Loans or Specified Refinancing Revolving Credit Commitments, and subject to the approval of the Applicable Administrative Agent (which approval shall not be unreasonably withheld, conditioned or delayed), the Borrower may
also invite additional Eligible Assignees to become Lenders in respect of such Specified Refinancing Term Loans or Specified Refinancing Revolving Credit Commitments, as applicable, pursuant to a joinder agreement to this Agreement in form and
substance reasonably satisfactory to the Applicable Administrative Agent. 

  
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 (d) The effectiveness of any Refinancing Amendment shall be subject to the satisfaction on the
date thereof of each of the conditions set forth in clause (a) above and Section 3.2, and delivery to the Applicable Administrative Agent of a certificate of the Borrower dated the date thereof signed by a Responsible Officer
of the Borrower, certifying and attaching the resolutions adopted by the Borrower approving such Specified Refinancing Term Loans or Specified Refinancing Revolving Credit Commitments, as applicable, and certifying that the conditions precedent set
forth in clause (a) above and Section 3.2 have been satisfied and, to the extent reasonably requested by the Applicable Administrative Agent, receipt by the Applicable Administrative Agent of legal opinions, board
resolutions, officers’ certificates and/or reaffirmation agreements, including any supplements or amendments to the Loan Documents providing for such Specified Refinancing Term Loans or Specified Refinancing Revolving Credit Commitments to be
secured thereby, all in form and substance reasonably satisfactory to the Applicable Administrative Agent. The Lenders hereby authorize the Administrative Agents and the Collateral Agent to enter into amendments to this Agreement and the other Loan
Documents with the Borrower and the other Loan Parties as may be necessary in order to establish new Tranches of Term Loans and Revolving Credit Commitments and to make such technical amendments as may be necessary or appropriate in the reasonable
opinion of the Applicable Administrative Agent and the Borrower in connection with the establishment of such new Tranches of Term Loans and Revolving Credit Commitments, in each case, on terms consistent with and/or to effect the provisions of this
Section 2.22. 
 (e) Each Tranche of Specified Refinancing Term Loans incurred under this Section 2.22 shall be in
an aggregate principal amount that is not less than $10,000,000. Each Tranche of Specified Refinancing Revolving Credit Commitments incurred under this Section 2.22 shall be in an aggregate amount that is not less than $10,000,000. 

(f) The Applicable Administrative Agent shall promptly notify each Lender as to the effectiveness of each Refinancing Amendment. Each of the
parties hereto hereby agrees that, upon the effectiveness of any Refinancing Amendment, this Agreement shall be deemed amended to the extent (but only to the extent) necessary to reflect the existence and terms of the Specified Refinancing Term
Loans or Specified Refinancing Revolving Credit Commitments incurred pursuant thereto (including for purposes of prepayments and voting). Any Refinancing Amendment may, without the consent of any Person other than the Borrower, the Administrative
Agents, the Collateral Agent and the Lenders providing such Specified Refinancing Term Loans or Specified Refinancing Revolving Credit Commitments, as applicable, effect such amendments to this Agreement and the other Loan Documents as may be
necessary or appropriate, in the reasonable opinion of the Administrative Agents and the Borrower, to effect the provisions of or consistent with this Section 2.22. 

Section 2.23 Extensions of Term Loans; Extensions of Revolving Loans. 

(a) Notwithstanding anything to the contrary in this Agreement, pursuant to one or more offers (each, an “Extension Request”)
made from time to time by the Borrower to all Lenders of Term Loans with a like Maturity Date or Revolving Credit Commitments (and related outstandings) with a like Maturity Date, in each case on a pro rata basis (based on the aggregate
outstanding principal amount of the respective Term Loans or Revolving Credit Commitments with a like Maturity Date, as the case may be) and on the same terms to each such Lender, the 

  
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Borrower is hereby permitted to consummate from time to time transactions with individual Lenders that accept the terms contained in such Extension Request to extend the Maturity Date of each
such Lender’s Term Loans and/or Revolving Credit Commitments and otherwise modify the terms of such Term Loans and/or Revolving Credit Commitments pursuant to the terms of the relevant Extension Request (including by increasing the interest
rate or fees payable in respect of such Term Loans and/or Revolving Credit Commitments (and related outstandings) and/or modifying the amortization schedule in respect of such Lender’s Term Loans) (each, an “Extension”, and
each group of Term Loans or Revolving Credit Commitments (and related outstandings), as applicable, in each case as so extended, as well as the original Term Loans and the original Revolving Credit Commitments (and related outstandings) (in each
case not so extended), being a “Tranche”; any Extended Term Loans shall constitute a separate Tranche of Term Loans from the Tranche of Term Loans from which they were converted and any Extended Revolving Credit Commitments shall
constitute a separate Tranche of Revolving Credit Commitments from the Tranche of Revolving Credit Commitments from which they were converted), so long as the following terms are satisfied: 

(i) except as to interest rates, fees, optional redemption or prepayment terms, final maturity, and after the final maturity
date of the Revolving Credit Commitment, any other covenants and provisions (which shall be determined by the Borrower and the relevant Revolving Credit Lenders and set forth in the relevant Extension Request), the Revolving Credit Commitment of any
Revolving Credit Lender (an “Extending Revolving Credit Lender”) extended pursuant to an Extension (an “Extended Revolving Credit Commitment” and the Revolving Loans thereunder, “Extended Revolving
Loans”), and the related outstandings, shall be a Revolving Credit Commitment (or related outstandings, as the case may be) with such other terms substantially identical to, or taken as a whole, no more favorable to the Revolving Credit
Lenders, as the original Revolving Credit Commitments (and related outstandings); provided that (1) the borrowing and repayment (except (A) for payments of interest and fees at different rates on Extended Revolving Credit
Commitments (and related outstandings), (B) for repayments required upon the maturity date of the non-extending Revolving Credit Commitments of Revolving Loans with respect to Extended Revolving Credit Commitments after the applicable Extension
date, and (C) as otherwise provided in Section 2.22 with respect to Specified Refinancing Revolving Credit Commitments that are unsecured or secured on a junior basis) shall be made on a pro rata basis with all other
Revolving Credit Commitments, (2) to the extent dealing with Letters of Credit and Swing Loans which mature or expire after a Maturity Date when there exist Extended Revolving Credit Commitments with a later Maturity Date, all Swing Loans and
Letters of Credit shall be participated on a pro rata basis by all Revolving Credit Lenders with Revolving Credit Commitments in accordance with their percentage of the Revolving Credit Commitments (without giving effect to changes thereto on
an earlier Maturity Date with respect to Letters of Credit theretofore incurred or issued, although the respective Extension Amendment may contain technical changes related to the borrowing, replacement Letter of Credit and Swing Loan procedures of
the Revolving Credit Commitments in respect of which the Extended Revolving Credit Commitments were extended), (3) the permanent repayment of Revolving Loans with respect to, and termination of, Extended Revolving Credit Commitments after the
applicable Extension date shall be made on a pro rata basis with all other Revolving Credit Commitments, except that the Borrower shall be permitted to permanently repay and terminate commitments of any Revolving Credit Facility on a better
than pro rata basis as compared 

  
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to any other Revolving Credit Facility with a later Maturity Date (x) if agreed to by the Revolving Credit Lenders in respect of such Revolving Credit Facility with a later Maturity Date in
the respective Extension Amendment or (y) if such Extended Revolving Credit Commitments are unsecured or secured on a junior basis, (4) assignments and participations of Extended Revolving Credit Commitments shall be governed by the same
assignment and participation provisions applicable to Revolving Credit Commitments (and related outstandings) and (5) at no time shall there be Revolving Credit Commitments hereunder (including Extended Revolving Credit Commitments, Specified
Refinancing Revolving Credit Commitments and any original Revolving Credit Commitments) which have more than three different Maturity Dates; 

(ii) except as to interest rates, fees, amortization, final maturity date, optional prepayments, premium, required prepayment
dates and participation in prepayments (which shall, subject to immediately succeeding clauses (iii), (iv) and (vi), be determined by the Borrower and the Extending Term Lenders and set forth in the relevant Extension
Request), the Term Loans of any Lender that agrees to an Extension with respect to such Term Loans (each an “Extending Term Lender”, together with the Extending Revolving Credit Lenders the “Extending Lenders”)
extended pursuant to any Extension (“Extended Term Loans”) shall be substantially identical to, or (taken as a whole) no more favorable to the Extending Term Lenders than those applicable to the Term Loans subject to such Extension
Request (except for covenants or other provisions applicable only to periods after the Latest Maturity Date then in effect); 

(iii) the final maturity date of any Extended Term Loans shall be no earlier than the Maturity Date of the Term Loans extended
thereby; 
 (iv) the Weighted Average Life to Maturity of any Extended Term Loans shall be no shorter than the remaining
Weighted Average Life to Maturity of the Term Loans extended thereby; 
 (v) the Extended Term Loans and the Extended
Revolving Credit Commitments shall not be (A) secured by any Lien on any asset other than the Collateral and (B) guaranteed by any Person other than the Guarantors; 

(vi) subject to the proviso contained in clause (x) of Section 2.12(a), any Extended Term Loans may
participate on a pro rata basis or a less than pro rata basis (but not greater than a pro rata basis) in any optional or mandatory repayments or prepayments hereunder, in each case as specified in the
respective Extension Request; 
 (vii) if the aggregate principal amount of Term Loans (calculated on the face amount
thereof) or Revolving Credit Commitments, as the case may be, in respect of which Term Lenders or Revolving Credit Lenders, as the case may be, shall have accepted the relevant Extension Request shall exceed the maximum aggregate principal amount of
Term Loans or Revolving Credit Commitments, as the case may be, offered to be extended by the Borrower pursuant to such Extension Request, then the Term Loans or Revolving Credit Commitments, as the case may be, of such Term Lenders or Revolving
Credit Lenders, as the case may be, shall be extended ratably up to such maximum amount based on the respective principal amounts (but not to exceed actual holdings of record) with respect to which such Term Lenders or Revolving Credit Lenders, as
the case may be, have accepted such Extension Request (subject to rounding required by the Administrative Agents); and 

  
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 (viii) all documentation in respect of such Extension shall be consistent with
the foregoing. No Lender shall have any obligation to agree to have any of its Term Loans or Revolving Credit Commitments extended pursuant to an Extension Request. 

(b) With respect to all Extensions consummated by the Borrower pursuant to this Section 2.23, (i) such Extensions shall not
constitute optional or mandatory payments or prepayments for purposes of Section 2.7 or 2.8 and (ii) no Extension Request is required to be in any minimum amount or any minimum increment. The Administrative Agents and the
Lenders hereby consent to the Extensions and the other transactions contemplated by this Section 2.23 (including, for the avoidance of doubt, payment of any interest, fees or premium in respect of any Extended Term Loans and/or Extended
Revolving Credit Commitments, as the case may be, on such terms as may be set forth in the relevant Extension Request) and hereby waive the requirements of any provision of this Agreement (including Sections 2.7, 2.8, 2.12(a)
and 2.12(b)) or any other Loan Document that may otherwise prohibit any such Extension or any other transaction contemplated by this Section 2.23. 

(c) The Borrower shall provide the applicable Extension Request at least 5 Business Days (or such shorter period as the Applicable
Administrative Agent may determine in its sole discretion) prior to the date on which Lenders under the applicable Tranche of Term Loans or Revolving Credit Commitments are requested to respond, and shall agree to such procedures, if any, as may be
established by, or acceptable to, the Applicable Administrative Agent, in each case acting reasonably, to accomplish the purpose of this Section 2.23. Any Extending Lender wishing to have all or a portion of its Term Loans or Revolving
Credit Commitments subject to such Extension Request converted into Extended Term Loans or Extended Revolving Credit Commitments, as applicable, shall notify the Applicable Administrative Agent (an “Extension Election”) on or prior
to the date specified in such Extension Request of the amount of its existing Term Loans or Revolving Credit Commitments subject to such Extension Request that it has elected to convert into Extended Term Loans or Extended Revolving Credit
Commitments, as applicable (subject to any minimum denomination requirements imposed by the Applicable Administrative Agent and proration as provided in clause (vii) of Section 2.23(a)). Any Lender not responding within the
requested time period shall be deemed to have declined to participate in the respective Extension. 
 (d) Extended Term Loans and Extended
Revolving Credit Commitments, as applicable, shall be established pursuant to an amendment (an “Extension Amendment”) to this Agreement and, if reasonably requested by the Applicable Administrative Agent, the other Loan Documents
(which, except to the extent expressly contemplated by the penultimate sentence of this Section 2.23(d) and notwithstanding anything to the contrary set forth in Section 11.1, shall not require the consent of any Lender other
than the Extending Lenders with respect to the Extended Term Loans or Extended Revolving Credit Commitments, as applicable, established thereby) executed by the Loan Parties, the Applicable Administrative Agent, the Collateral Agent and the
respective Extending Lenders. In addition to any terms and changes required or permitted by Section 2.23(a), each Extension Amendment may amend this Agreement to ensure ratable participation in Letters of Credit and Swing Loans by
Extended Revolving Credit Commitments. It is understood and agreed that each Lender hereunder has consented, and shall at the effective time thereof be deemed to consent, to each amendment to this Agreement and the other Loan Documents authorized by
this Section 2.23 and the arrangements described above in connection therewith. 

  
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 (e) In connection with any Extension Amendment, the Borrower shall deliver an opinion of counsel
reasonably acceptable to the Applicable Administrative Agent (i) as to the enforceability of such Extension Amendment, this Agreement as amended thereby, and such of the other Loan Documents (if any) as may be amended thereby (in the case of
such other Loan Documents as contemplated by the immediately preceding sentence) and (ii) covering such other matters as the Applicable Administrative Agent may reasonably request in connection therewith. 

(f) In the event that the Applicable Administrative Agent determines in its sole discretion that the allocation of Extended Term Loans or
Extended Revolving Credit Commitments to a given Lender was incorrectly determined as a result of manifest administrative error in the receipt and processing of an Extension Election timely submitted by such Lender in accordance with the procedures
set forth in the applicable Extension Amendment, then the Applicable Administrative Agent, the Borrower and such affected Lender may (and hereby are authorized to), in their sole discretion and without the consent of any other Lender, enter into
an amendment to this Agreement and the other Loan Documents (each, a “Corrective Extension Amendment”) within 15 days following the effective date of such Extension Amendment, as the case may be, which Corrective Extension
Amendment shall (i) provide for the conversion and extension of Revolving Credit Commitments (and related Revolving Credit Outstandings) or Term Loans, as the case may be, in such amount as is required to cause such Lender to hold Extended
Revolving Credit Commitments (and related Revolving Credit Outstandings) or Extended Term Loans, as the case may be, in the amount such Lender would have held had such administrative error not occurred and had such Lender received the minimum
allocation of the applicable Term Loans or Revolving Credit Commitments to which it was entitled under the terms of such Extension Amendment, in the absence of such error, (ii) be subject to the satisfaction of such conditions as the
Applicable Administrative Agent, the Borrower and such Lender may agree (including conditions of the type required to be satisfied for the effectiveness of an Extension Amendment described in Section 2.23(d)), and
(iii) effect such other amendments of the type (with appropriate reference and nomenclature changes) described in the penultimate sentence of Section 2.23(d). 

(g) No exchange or conversion of Term Loans or Revolving Credit Commitments pursuant to any Extension Amendment in accordance with this
Section 2.23 shall (x) be made at any time an Event of Default shall have occurred and be continuing (and no Extension Request shall be delivered to the Lenders at any time an Event of Default shall have occurred and be continuing)
and (y) constitute an optional or mandatory payment or prepayment for purposes of this Agreement. 
 ARTICLE III 

CONDITIONS TO LOANS AND LETTERS OF CREDIT 

Section 3.1 Conditions Precedent to Loans and Letters of Credit on the Closing Date. The obligation of each Lender to make
any Loan on the Closing Date and the obligation of each 

  
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L/C Issuer to Issue any Letter of Credit on the Closing Date are subject to the satisfaction or due waiver by the Lenders of each of the following conditions precedent: 

(a) Certain Documents. The Administrative Agents shall have received on or prior to the Closing Date each of the following, each dated
as of the Closing Date unless otherwise agreed by the Administrative Agents, in form and substance reasonably satisfactory to the Administrative Agents: 

(i) this Agreement duly executed by the Borrower and, for the account of each Lender having requested the same by notice to the
Applicable Administrative Agent and the Borrower received by each at least 3 Business Days prior to the Closing Date (or such later date as may be agreed by the Borrower), Notes in each applicable Facility conforming to the requirements set forth in
Section 2.14(e); 
 (ii) the Guaranty and Security Agreement, duly executed by each Loan Party, together with
(A) copies of UCC, Intellectual Property and other appropriate search reports and of all effective prior filings listed therein, together with evidence of the termination of such prior filings and other documents (other than with respect to
Permitted Liens) with respect to the priority of the security interest of the Collateral Agent in the Collateral, in each case as may be reasonably requested by either Administrative Agent, (B) except to the extent otherwise expressly provided
under Section 7.13 or as may be agreed to by the Administrative Agents, all documents representing all Securities, chattel paper and instruments being pledged pursuant to such Guaranty and Security Agreement and related undated powers or
endorsements duly executed in blank, and (C) except to the extent otherwise expressly provided under Section 7.13, all Control Agreements that, in the reasonable judgment of the Administrative Agents, are required for the Loan
Parties to comply with the Loan Documents as of the Closing Date, each duly executed by the parties thereto; 
 (iii) a
pledge agreement in respect of 66% of the issued Stock in Swissco, governed by Swiss law, duly executed by Alere International Holding Corp. (as amended, modified, restated and/or supplemented from time to time, the “Swiss Pledge
Agreement”), together with all share certificates and undated powers or endorsements duly executed in blank in relation to 66% of the issued Stock of Swissco, and Alere International Holding Corp. and Swissco shall have taken such actions
as may be necessary or advisable under local law (as advised by local counsel) to create, effect, perfect, preserve, maintain and protect the security interests granted (or purported to be granted) thereby; 

(iv) (A) from (1) Foley Hoag LLP, special counsel to the Loan Parties in Delaware and New York, (2) Perkins Coie LLP,
special counsel to the Loan Parties in California, (3) Troutman Sanders LLP, special counsel to the Loan Parties in Virginia, (4) Jones Walker LLP, special counsel to the Loan Parties in Florida and Louisiana and (5) Crowe &
Dunlevy, A Professional Corporation, special counsel to the Loan Parties in Oklahoma, in each case, duly executed favorable legal opinions satisfactory to the Administrative Agent, each addressed to the Administrative Agents, the Collateral Agent,
the L/C Issuers and the Lenders (and their respective successors and assigns) and addressing such matters as either Administrative Agent may reasonably request, and (B) from Schellenberg Wittmer, Swiss counsel to the Administrative Agents, a
duly executed favorable legal opinion with respect to the validity and enforceability of the Swiss Pledge Agreement, addressed to the Administrative Agents, the Collateral Agent, the L/C Issuer and the Lenders (and their respective successors and
assigns); 

  
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 (v) a copy of each Constituent Document of each Loan Party that is on file with
any Governmental Authority in any jurisdiction, certified as of a recent date by such Governmental Authority, together with, if applicable, certificates attesting to the good standing of such Loan Party in such jurisdiction; 

(vi) a certificate of the secretary, assistant secretary or other officer of each Loan Party in charge of maintaining books and
records of such Loan Party certifying as to (A) the names and signatures of each officer of such Loan Party authorized to execute and deliver any Loan Document and who will execute any such Loan Document, (B) the Constituent Documents of
such Loan Party attached to such certificate are complete and correct copies of such Constituent Documents as in effect on the date of such certification (or, for any such Constituent Document delivered pursuant to clause (v) above, that
there have been no changes from such Constituent Document so delivered) and (C) except to the extent otherwise expressly provided under Section 7.13, the resolutions of such Loan Party’s board of directors or other appropriate
governing body approving and authorizing the execution, delivery and performance of each Loan Document to which such Loan Party is a party; 

(vii) a certificate of a Responsible Officer of the Borrower to the effect that (x) each condition set
forth in Section 3.2(b) has been satisfied and (y) the Corporate Chart attached thereto is current and complete in all material respects as of the Closing Date; 

(viii) a certificate of a Responsible Officer of the Borrower, dated the Closing Date, to the effect that the Borrower and its
Subsidiaries taken as a group on a consolidated basis are Solvent after giving effect to the initial Loans and Letters of Credit, the consummation of the Transactions, the application of the proceeds thereof in accordance with
Section 7.9 and the payment of all estimated legal, accounting and other fees and expenses related hereto and thereto; 

(ix) insurance certificates in form and substance satisfactory to the Administrative Agents demonstrating that the insurance
policies required by Section 7.5 are in full force and effect and have all endorsements required by such Section 7.5; 

(x) copies of the financial statements and projections referred to in Section 4.4; and 

(xi) such other documents and information as either Administrative Agent may reasonably request. 

(b) Fees and Expenses. (i) There shall have been paid to each Administrative Agent, for the account of such Administrative Agent,
its Related Persons, any L/C Issuer, any Arranger or any Lender, as the case may be, all fees and all reimbursements of costs or expenses, in each case due and payable under any Loan Document or the Engagement Letter on or before the Closing Date
and which are presented to the Borrower no less than one Business Day prior to the Closing Date. 
 (ii) The Borrower shall
have paid to the Applicable Administrative Agent for the benefit of each Lender which holds A Term Loan Commitments, B Term Loan Commitments and/or Revolving Credit Commitments as of the Closing Date, an

  
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initial upfront commitment fee in an amount equal to (x) with respect to the A Term Loan Commitments, 0.50% of the amount of the A Term Loan Commitment of each such Lender as of the Closing
Date, (y) with respect to the B Term Loan Commitments, 0.25% of the amount of the B Term Loan Commitment of each such Lender as of the Closing Date, and (z) with respect to the Revolving Credit Commitments, 0.50% of the amount of the
Revolving Credit Commitment of each such Lender as of the Closing Date. 
 (c) Refinancing; Indebtedness. 

(i) On the Closing Date and concurrently with the funding of the Loans hereunder, all Indebtedness under the Existing Credit
Agreement shall have been repaid or redeemed in full and all commitments in respect thereof shall have been terminated and all Liens and guaranties in connection therewith shall have been terminated (as evidenced by a payoff letter, appropriate
releases (including Intellectual Property and mortgage releases), termination statements, instruments of assignment or other documentation reasonably satisfactory to the Administrative Agents). 

(ii) On the Closing Date and after giving effect to the consummation of the Transactions, the Borrower and its Subsidiaries
shall have no outstanding Indebtedness, except for (i) Indebtedness pursuant to or in respect of the Loan Documents and (ii) other Indebtedness permitted by Section 8.1. The Administrative Agents shall have received evidence in
form, scope and substance reasonably satisfactory to it that the matters set forth in this Section 3.1(c) have been satisfied on the Closing Date. 

(d) Existing Notes. No consents or approvals shall be required to be obtained by the Borrower or any of its Subsidiaries from the
holders of any of the Existing Notes in connection with the entering into of this Agreement, any of the other Loan Documents or other documents referred herein (including, without limitation, any of the Security Documents) and the incurrence of all
Loans hereunder. The Administrative Agents shall have received evidence (including appropriate legal opinions and a certificate of a Responsible Officer of the Borrower) in form, scope and substance reasonably satisfactory to it that the matters set
forth in this clause (d) have been satisfied. 
 (e) Public Debt Ratings. On or prior to the Closing Date, the Borrower
shall have obtained (i) debt ratings (of any level) from S&P and Moody’s in respect of each Tranche of Loans existing on the Closing Date and (ii) corporate credit and corporate family ratings (of any level) from S&P and
Moody’s, each of which ratings shall be in effect on the Closing Date. 
 (f) Patriot Act. At least 3 Business Days prior to the
Closing Date, the Administrative Agents and the Lenders shall have received all documentation and other information required by regulatory authorities under applicable “know your customer” and anti-money laundering rules and regulations,
including the Patriot Act, in each case to the extent requested in writing at least five Business Days prior to the Closing Date. 

Section 3.2 Conditions Precedent to Each Loan and Letter of Credit. The obligation of each Lender on any date (including the
Closing Date) to make any Loan and of each L/C Issuer 

  
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on any date (including the Closing Date) to Issue any Letter of Credit is subject to the satisfaction of each of the following conditions precedent: 

(a) Request. The Applicable Administrative Agent (and, in the case of any Issuance, the relevant L/C Issuer) shall have received, to
the extent required by Article II, a written, timely and duly executed and completed Notice of Borrowing, Swingline Request or, as the case may be, L/C Request. 

(b) Representations and Warranties; No Defaults. The following statements shall be true on such date, both before and after giving
effect to such Loan or, as applicable, such Issuance: (i) the representations and warranties set forth in any Loan Document shall be true and correct in all material respects (provided that if any representation or warranty is by its terms
qualified by concepts of materiality, such representation shall be true and correct in all respects) on and as of such date or, to the extent such representations and warranties expressly relate to an earlier date, on and as of such earlier date and
(ii) no Default or Event of Default shall be continuing. 
 The representations and warranties set forth in any Notice of Borrowing, Swingline Request
or L/C Request (or any certificate delivered in connection therewith) shall be deemed to be made again on and as of the date of the relevant Loan or Issuance and the acceptance of the proceeds thereof or of the delivery of the relevant Letter of
Credit. 
 Section 3.3 Determinations of Initial Borrowing Conditions. For purposes of determining compliance with the
conditions specified in Section 3.1, each Lender shall be deemed to be satisfied with each document and each other matter required to be satisfactory to such Lender unless, prior to the Closing Date, both Administrative Agents receive notice
from such Lender specifying such Lender’s objections and such Lender has not made available its Pro Rata Share of any Borrowing scheduled to be made on the Closing Date. 

ARTICLE IV 
 REPRESENTATIONS AND
WARRANTIES 
 To induce the Lenders, the L/C Issuers, the Collateral Agent and the Administrative Agents to enter into the Loan Documents,
the Borrower (and, to the extent set forth in any other Loan Document, each other Loan Party) represents and warrants to each of them each of the following on and as of each date applicable pursuant to Section 3.2: 

Section 4.1 Corporate Existence; Compliance with Law. Each Group Member (a) is duly organized, validly existing and in
good standing under the laws of the jurisdiction of its organization, (b) is duly qualified to do business as a foreign entity and in good standing under the laws of each jurisdiction where such qualification is necessary, except where the
failure to be so qualified or in good standing could not reasonably be expected to have, either individually or in the aggregate, a Material Adverse Effect, (c) has, in all material respects, all requisite power and authority and the legal
right to own, pledge, mortgage and operate its property, to lease or sublease any property it operates under lease or sublease and to conduct its business as now or currently proposed to be conducted, (d) is in compliance with its Constituent
Documents, (e) is in compliance with all applicable Requirements of Law (including all Healthcare Laws), except where the failure to be in compliance could not reasonably be expected to have, either individually or in the aggregate, a Material
Adverse Effect, and (f) has all necessary Permits from or by, has made all necessary filings with, and has given all necessary notices to, each Governmental Authority having jurisdiction, to the extent required for such ownership, lease,
sublease, operation, occupation or conduct of business, except where the failure to obtain such Permits, make such filings or give such notices could not reasonably be expected to have, either individually or in the aggregate, a Material Adverse
Effect. 

  
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 Section 4.2 Loan Documents. 

(a) Power and Authority. The execution, delivery and performance by each Loan Party of the Loan Documents to which it is a party and the
consummation by each Loan Party of the Transactions and other transactions contemplated herein (i) are within such Loan Party’s corporate or similar powers and, at the time of execution thereof, have been duly authorized by all necessary
corporate and similar action (including, if applicable, consent of holders of its Securities), (ii) do not (A) contravene such Loan Party’s Constituent Documents, (B) violate any Requirement of Law, (C) conflict with,
contravene, constitute a default or breach under, any Contractual Obligation of any Loan Party or any of its Subsidiaries, other than those which could not reasonably be expected to have, either individually or in the aggregate, a Material Adverse
Effect, or (D) result in the imposition of any Lien (other than a Permitted Lien) upon any property of any Loan Party or any of its Subsidiaries and (iii) do not require any Loan Party to obtain any Permit of, or make any filing with, any
Governmental Authority or obtain any consent of, or notice to, any Person, other than (A) with respect to the Loan Documents, the filings required to perfect the Liens created by the Loan Documents, (B) filings of (or relating to) the Loan
Documents after the Closing Date with the SEC pursuant to the Borrower’s public disclosure obligations under applicable United States federal securities laws and/or the rules of any securities exchange on which the Borrower’s securities
are listed and (C) those listed on Schedule 4.2, which unless otherwise noted on such schedule, have been or will otherwise be prior to the Closing Date, obtained or made, copies of which (other than those so noted as not yet obtained or
made) have been, or will be prior to the Closing Date, delivered to the Administrative Agents to the extent requested by either Administrative Agent, and which (other than those so noted as not yet obtained or made) on the Closing Date will be in
full force and effect 
 (b) Due Execution and Delivery. From and after its delivery to the Administrative Agents, each Loan Document
has been duly executed and delivered to the other parties thereto by each Loan Party, is the legal, valid and binding obligation of such Loan Party and is enforceable against such Loan Party in accordance with its terms, except as may be limited by
applicable bankruptcy, insolvency, reorganization, moratorium, fraudulent transfer or other similar laws affecting creditors’ rights generally or by general equitable principles relating to enforceability. 

(c) Existing Notes. The full amount of the Loans (excluding any undrawn or uncommitted Incremental Term Loans, Specified Refinancing
Term Loans and Extended Term Loans until such time as such Incremental Term Loans, Specified Refinancing Term Loans and Extended Term Loans, as applicable, are so borrowed) may be incurred under the Existing Notes Indentures and all Obligations
constitute “Senior Debt” or “Senior Indebtedness”, as applicable, and “Designated Senior Debt” or “Designated Senior Indebtedness”, as applicable, under, and as defined in, the Existing Subordinated Notes
Indentures. After giving effect to the Refinancing, no other Indebtedness of any Group Member qualifies as “Designated Senior Debt” or “Designated Senior Indebtedness”, as applicable, under the Existing Subordinated Notes
Indentures. 
 Section 4.3 Ownership of Group Member. (a) Set forth on Schedule 4.3(a) is a complete and
accurate list showing, as of the Closing Date, for each Group Member (other than the Borrower), its jurisdiction of organization, and the number (in the case of the Loan 

  
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Parties and any Excluded Foreign Subsidiary that is a first tier Subsidiary of any Loan Party) and percentage of the outstanding shares of each class of Stock owned (directly or indirectly) by
the applicable holder thereof. As of the Closing Date, all outstanding Stock owned by any Group Member in any other Group Member has been validly issued, is fully paid and non-assessable (to the extent applicable) and is owned beneficially and of
record by a Group Member free and clear of all Liens other than the security interests created by the Loan Documents and, in the case of joint ventures, Permitted Liens. Except as set forth on Schedule 4.3(a), as of the Closing Date, there
are no Stock Equivalents with respect to the Stock of any Group Member (other than the Borrower) or any Contractual Obligations to which any Group Member (other than the Borrower) is a party with respect to (including any restriction on) the
issuance, voting, Sale or pledge of any Stock or Stock Equivalent of any Group Member (other than the Borrower). 
 (b) Set forth on
Schedule 4.3(b) is a complete and accurate list, as of the Closing Date, of all material agreements and documents relating to the P&G Joint Venture. 

(c) None of the Inactive Subsidiaries as of the Closing Date engage in any business, operations or activity, or hold any property, other than
as permitted under Section 8.8(c). 
 (d) As of the Closing Date, there are no Unrestricted Subsidiaries. 

Section 4.4 Financial Statements. (a) Each of (i) the audited Consolidated balance sheet of the Borrower as at
December 31, 2014 and the related Consolidated statements of operations, equity and comprehensive income (loss) and cash flows of the Borrower for the Fiscal Year then ended, audited by PricewaterhouseCoopers LLP, and (ii) subject to the
absence of footnote disclosure and normal year-end audit adjustments, the unaudited Consolidated balance sheet of the Borrower as at March 31, 2015 and the related Consolidated statements of income and cash flows of the Borrower for the three
months then ended, copies of each of which have been furnished to the Administrative Agents prior to the Closing Date, fairly present in all material respects the Consolidated financial position, results of operations and cash flows of the Borrower
and its Subsidiaries as at the dates indicated and for the periods indicated in accordance with GAAP. 
 (b) On the Closing Date, except as
set forth on Schedule 4.4(b), (i) no Group Member has any material liability or other obligation (including Indebtedness, Guaranty Obligations, contingent liabilities and liabilities for taxes, long-term leases and unusual forward or
long-term commitments) that is not reflected in the Financial Statements referred to in clause (a) above or in the notes thereto, that has not been publicly disclosed in any SEC filing of the Borrower, and that is prohibited by this
Agreement and (ii) since the date of the unaudited Financial Statements referenced in clause (a) above, there has been no Sale of any material property of any Group Member and no purchase or other acquisition of any material
property that has not be disclosed to the public or to the Administrative Agents and that would have been required to have been disclosed to the Administrative Agents under the terms of this Agreement had this Agreement been in effect since such
date. 
 (c) The Initial Projections have been prepared by the Borrower in light of the past operations of the business of the Borrower and
its Subsidiaries and reflect projections for the Fiscal Years ending in 2015 through 2021. As of the Closing Date, the Initial Projections are based upon estimates and assumptions stated therein, all of which the Borrower believes to be reasonable
and fair in light of conditions and facts known to the Borrower as of the Closing Date 

  
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and reflect the good faith estimates by the Borrower of the future Consolidated financial performance of the Borrower and the other information projected therein for the periods set forth
therein; provided that (i) such Initial Projections are forward looking information which may be subject to significant uncertainties and contingencies beyond the Group Members’ control, (ii) no assurance would be given by the
Group Members that such Initial Projections will be realized and (iii) the actual results may differ from the Initial Projections and such differences might be material. 

Section 4.5 Material Adverse Effect. Since December 31, 2014, there have been no events, circumstances, developments or
other changes in facts, including changes in the status of any matter described in Section 4.7, that have had, or could reasonably be expected to have, either individually or in the aggregate, a Material Adverse Effect. 

Section 4.6 Solvency. Both before and after giving effect to (a) the Loans and Letters of Credit made or Issued on or
prior to the date this representation and warranty is made, (b) the disbursement of the proceeds of such Loans, (c) the consummation of the Transactions and (d) the payment and accrual of all transaction costs in connection with the
foregoing, the Borrower and its Subsidiaries taken as a group on a consolidated basis are Solvent. 
 Section 4.7
Litigation. Except as set forth in Schedule 4.7, there are no pending (or, to the knowledge of any Group Member, threatened) actions, investigations, suits, proceedings, audits, claims, demands, orders, notices of violation or disputes
affecting the Borrower or any of its Subsidiaries with, by or before any Governmental Authority, other than those that cannot reasonably be expected, either individually or in the aggregate, to have a Material Adverse Effect. No injunction, writ,
temporary restraining order or any order of any nature has been issued by any court or other Governmental Authority purporting to enjoin or restrain the execution, delivery or performance of this Agreement or any other Loan Document, or directing
that the transactions provided for herein or therein not be consummated as herein or therein provided. 
 Section 4.8
Taxes. Except, in the case of each of succeeding clauses (i), (ii) and (iii), as set forth in Schedule 4.8 or as could not reasonably be expected to have, either individually or in the aggregate, a Material
Adverse Effect: (i) all federal, state, local and foreign income and franchise and other material tax returns, reports and statements, in each case relating to taxes, (collectively, the “Tax Returns”) required to be filed
(giving effect to any available extension periods) by any Tax Affiliate have been filed with the appropriate Governmental Authorities in all jurisdictions in which such Tax Returns are required by law to be filed, all such Tax Returns are true and
correct in all material respects, and all taxes, charges and other impositions reflected therein or otherwise due and payable have been paid prior to the date on which any Liability may be added thereto for non-payment thereof, except for those
amounts contested in good faith by appropriate proceedings diligently conducted and for which adequate reserves are maintained on the books of the appropriate Tax Affiliate in accordance with GAAP; (ii) no Tax Return is under audit or
examination by any Governmental Authority and no written notice of such an audit or examination or any written assertion of any claim for Taxes has been given or made by any Governmental Authority, which audit, examination or claim has not been
resolved; and (iii) no Tax Affiliate has participated in a “reportable transaction” within the meaning of Treasury Regulation Section 1.6011-4(b) or has been a member of an affiliated, combined or unitary group other than the
group of which a Tax Affiliate is the common parent. 
 Section 4.9 Margin Regulations. (a) The Borrower is not
engaged in the business of extending credit for the purpose of, and no proceeds of any Loan or other extensions of credit 

  
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hereunder will be used for the purpose of, buying or carrying Margin Stock or extending credit to others for the purpose of purchasing or carrying any such Margin Stock, in each case in
contravention of Regulation T, U or X of the Federal Reserve Board. 
 (b) Except to the extent permitted by Section 7.14, the
fair market value of all Margin Stock owned by the Borrower and its Subsidiaries (other than Stock of the Borrower held in treasury) does not exceed $35,000,000. At the time of making of each Loan or issuance of each Letter of Credit, not more than
25% of the value of the assets of the Borrower and its Subsidiaries taken as a whole (including all Stock of the Borrower held in treasury) will constitute Margin Stock. 

Section 4.10 No Burdensome Obligations; No Defaults. No Group Member is a party to any Contractual Obligation, no Group Member
has Constituent Documents containing obligations, and, to the knowledge of any Group Member, there are no applicable Requirements of Law (including all Healthcare Laws), in each case the compliance with which could reasonably be expected to have,
either individually or in the aggregate, a Material Adverse Effect. No Group Member (and, to the knowledge of each Group Member, no other party thereto) is in default under or with respect to any Contractual Obligation of any Group Member, other
than those that could not reasonably be expected to have, either individually or in the aggregate, a Material Adverse Effect. 

Section 4.11 Investment Company Act. No Group Member is an “investment company” or an “affiliated
person” of, or “promoter” or “principal underwriter” for, an “investment company”, as such terms are defined in the Investment Company Act of 1940. 

Section 4.12 Labor Matters. (a) Except as set forth on Schedule 4.12, there are no strikes, work stoppages,
slowdowns or lockouts existing, pending (or, to the knowledge of any Group Member, threatened) against or involving any Group Member, except for those that could not reasonably be expected to have, either individually or in the aggregate, a Material
Adverse Effect; (b) hours worked by and payment made to employees of each Group Member comply with the Fair Labor Standards Act and each other federal, state, local or foreign law applicable to such matters, except where the failures to so
comply would not constitute, either individually or in the aggregate, a Material Adverse Effect; (c) as of the Closing Date, no Loan Party is party to or bound by any collective bargaining or similar agreement with any union, labor
organization, works council or similar representative covering any employee of any Loan Party; (d) as of the Closing Date, no Group Member which is not Loan Party is party to or bound by any collective bargaining or similar agreement with any
union, labor organization, works council or similar representative covering any employee of any such Group Member, except, for those that could not reasonably be expected to have, either individually or in the aggregate, a Material Adverse Effect;
(e) as of the Closing Date, there is no organizing activity involving any Group Member pending or, to any Group Member’s knowledge, threatened by any labor union or group of employees, except, for those that could not reasonably be
expected to have, either individually or in the aggregate, a Material Adverse Effect; (f) as of the Closing Date, no petition for certification or election of any such representative is existing or pending with respect to any employee of any
Group Member and no such representative has sought certification or recognition with respect to any employee of any Group Member, except for those that could not reasonably be expected to have, either individually or in the aggregate, a Material
Adverse Effect; and (g) there are no complaints or charges against any Group Member pending or, to the knowledge of any Group Member, threatened to be filed with any Governmental Authority or arbitrator based on, arising out of, in connection
with, or otherwise relating to the employment or termination of employment by any Group Member of any individual, except for complaints or charges that, either individually or in the aggregate, could not reasonably be expected to have a Material
Adverse Effect. 

  
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 Section 4.13 ERISA. (a) Each Benefit Plan, and each trust thereunder,
intended to qualify for tax exempt status under Section 401 or 501 of the Code or other Requirements of Law so qualifies, except where such noncompliances, either individually or in the aggregate, could not reasonably be expected to have a
Material Adverse Effect. Each Benefit Plan is in compliance with applicable provisions of ERISA, the Code and other Requirements of Law, except where such noncompliances, either individually or in the aggregate, could not reasonably be expected to
have a Material Adverse Effect. No Group Member or any ERISA Affiliate has engaged in any “prohibited transactions” as defined in Section 406 of ERISA and Section 4975 of the Code, in connection with any Benefit Plan, that would
subject any Group Member to a tax on prohibited transactions imposed by Section 502(i) of ERISA or Section 4975 of the Code that, either individually or in the aggregate, could reasonably be expected to have a Material Adverse Effect. On
the Closing Date, no ERISA Event has occurred in connection with which obligations and liabilities (contingent or otherwise) remain outstanding. 

(b) (i) No Title IV Plan has any Unfunded Pension Liability that, either individually or in the aggregate, could reasonably be expected to
result in a Material Adverse Effect; (ii) there are no existing or pending (or to the knowledge of any Group Member, threatened) claims (other than routine claims for benefits in the normal course), sanctions, actions, lawsuits or other
proceedings or investigation involving any Benefit Plan that, either individually or in the aggregate, could reasonably be expected to result in a Material Adverse Effect; (iii) within the last five years, no Title IV Plan of any Group Member
or ERISA Affiliate has been terminated, other than in a “standard termination” as that term is used in Section 4041(b)(1) of ERISA; and (iv) no ERISA Event has occurred that, either individually or in the aggregate, could
reasonably be expected to result in a Material Adverse Effect or a Lien under ERISA or Code Sections 412 or 430. 
 Section 4.14
Environmental Matters. Except, in the case of each of succeeding clauses (a), (b), (c) and (d), as set forth on Schedule 4.14 or as could not, either individually or in the aggregate, reasonably be
expected to have a Material Adverse Effect, (a) the operations of each Group Member are and have been in compliance with all applicable Environmental Laws, including obtaining, maintaining and complying with all Permits required by any
applicable Environmental Law, (b) no Group Member is party to, and no Group Member and no real property currently (or to the knowledge of any Group Member previously) owned, leased, subleased, operated or otherwise occupied by or for any Group
Member is subject to or the subject of, any Contractual Obligation or any pending (or, to the knowledge of any Group Member, threatened) order, action, investigation, suit, proceeding, audit, claim, demand, dispute or notice of violation or of
potential liability or similar notice under or pursuant to any Environmental Law, (c) no Lien in favor of any Governmental Authority securing, in whole or in part, Environmental Liabilities has attached to any property of any Group Member and,
to the knowledge of any Group Member, no facts, circumstances or conditions exist that could reasonably be expected to result in any such Lien attaching to any such property, and (d) no Group Member has caused or suffered to occur a Release of
Hazardous Materials at, to or from any real property of any Group Member and each such real property is free of contamination by any Hazardous Materials. 

  
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 Section 4.15 Intellectual Property. Each Group Member owns or licenses or
otherwise has the right to use all Intellectual Property that is necessary for the operations of its businesses, except for any failure to so own, license or have rights that could not reasonably be expected to have, either individually or in the
aggregate, a Material Adverse Effect. To the knowledge of each Group Member, (a) the conduct and operations of the businesses of each Group Member does not infringe, misappropriate, violate or otherwise impair any Intellectual Property owned by
any other Person and (b) no other Person has contested any right, title or interest of any Group Member in, or relating to, any Intellectual Property owned by such Group Member, other than, in the case of each of preceding clauses
(a) and (b), as could not reasonably be expected to have, either individually or in the aggregate, a Material Adverse Effect. Except, in the case of each of succeeding clauses (x) and (y), as set forth in
Schedule 4.15 or as could not reasonably be expected to have, either individually or in the aggregate, a Material Adverse Effect, (x) there are no pending (or, to the knowledge of any Group Member, threatened) actions, suits,
proceedings, audits, claims, demands, orders or disputes affecting any Group Member with respect to, and (y) no judgment or order regarding any such claim has been rendered by any competent Governmental Authority and no settlement agreement or
similar Contractual Obligation has been entered into by any Group Member with respect to, any such infringement, misappropriation, violation or impairment. 

Section 4.16 Title; Real Property. (a) Each Group Member has good and marketable fee simple title to all material
owned real property and valid leasehold interests in all material leased real property, and owns all material personal property, in each case that is purported to be owned or leased by it, including those reflected on the most recent Financial
Statements delivered by the Borrower, and none of such property is subject to any Lien except Permitted Liens. 
 (b) Set forth on
Schedule 4.16 is, as of the Closing Date, a complete and accurate list of all real property owned in fee simple by any Loan Party. 

Section 4.17 Bank and Security Accounts. Set forth on Schedule 4.17 is, as of the Closing Date, a complete and
accurate list of all bank, deposit, securities, commodities or other accounts maintained by any Loan Party, and such Schedule correctly identifies the name of each depository, the name in which the account is held, a description of the purpose of
the account, and the complete account number therefor. 
 Section 4.18 Insurance. Set forth on Schedule 4.18 is,
as of the Closing Date, a complete and accurate, in all material respects, list of all insurance policies of any nature maintained by each Loan Party, as well as a summary of the key business terms of each such policy such as deductibles, coverage
limits and term of policy. 
 Section 4.19 Use of Proceeds. (a) All proceeds of the Initial Term Loans will be used
by the Borrower (i) to finance the Refinancing, (ii) to pay the fees, costs and expenses incurred with the Transactions and (iii) to the extent in excess of the amounts required to be used pursuant to preceding clauses
(i) and (ii), for the general corporate purposes of the Borrower and its Subsidiaries (including Investments permitted hereunder). 

(b) The proceeds of all Incremental Term Loans will be used by the Borrower to finance Permitted Acquisitions (and to pay related fees, costs
and expenses) and for the working capital, Capital Expenditures and other general corporate purposes (including Investments permitted hereunder) of the Borrower and its Subsidiaries. 

  
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 (c) All proceeds of the Revolving Loans and the Swing Loans will be used to finance Permitted
Acquisitions (and to pay related fees, costs and expenses) and for the working capital, Capital Expenditures and other general corporate purposes of the Borrower and its Subsidiaries (including Investments permitted hereunder); provided that
proceeds of any Revolving Loans and Swing Loans drawn on the Closing Date may only be used to repay any then-outstanding loans and other amounts outstanding in respect of the revolving credit facility under the Existing Credit Agreement. 

(d) All proceeds of any Specified Refinancing Term Loans will be used solely for the purposes set forth in Section 2.22(b) and to
pay any related fees and expenses. 
 (e) All Letters of Credit will be issued to support obligations of the Borrower or any of its
Subsidiaries permitted hereunder (other than obligations in respect of any Junior Indebtedness or Stock). 
 Section 4.20
Full Disclosure. The information prepared or furnished by or on behalf of any Group Member to any Administrative Agent, any Arranger or any Lender in connection with any Loan Document (including the information contained in any Financial
Statement or Disclosure Document) or the consummation of any Transaction or any other transaction contemplated therein (excluding all projections that are part of such information), taken together with all other such information, does not contain
any untrue statement of a material fact or omit to state a material fact necessary to make the statements contained therein, in light of the circumstances when made, not misleading. All projections that are part of such information (including those
set forth in any Projections delivered subsequent to the Closing Date) are based upon estimates and assumptions stated therein believed to be reasonable and fair as of the date made in light of conditions and facts then known and, as of such date,
reflect good faith estimates of the information projected for the periods set forth therein; provided, however, (i) the projections (including all Projections) are forward looking statements and information which may be subject to
significant uncertainties and contingencies beyond the Group Members’ control, (ii) no assurance would be given by the Group Members that such projections will be realized and (iii) the actual results may differ from such projections
and such differences might be material. 
 Section 4.21 Anti-Money Laundering Laws; Anti-Corruption Laws; Anti-Terrorism
Laws; and Sanctions Laws and Regulations. 
 (a) The Borrower, each other Group Member, each director and officer of the Borrower and
each other Group Member, and, to the knowledge of the Borrower, each other Affiliate, agent or employee of the Borrower, are in compliance with the requirements of all Requirements of Laws relating to Anti-Money Laundering Laws, Anti-Corruption
Laws, Anti-Terrorism Laws and Sanctions Laws and Regulations and all orders, writs, injunctions and decrees applicable to it or to its properties, except to the extent that any non-compliance could not reasonably be expected to have, individually or
in the aggregate, a Material Adverse Effect. 
 (b) The Borrower and its Subsidiaries have implemented and maintain in effect policies and
procedures which are designed to ensure compliance in all material respects by the Borrower, each other Group Member and their respective directors, Affiliates, officers, employees and agents with Anti-Money Laundering Laws, Anti-Corruption Laws,
Anti-Terrorism Laws and applicable Sanctions Laws and Regulations. 

  
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 (c) None of the Borrower, any other Group Member, any director or officer of the Borrower or any
other Group Member, nor, to the knowledge of the Borrower, any other Affiliate, agent, or employee of the Borrower or any other Group Member, (i) is a Designated Person or (ii) is, or is owned or controlled by an entity or Person that is,
otherwise the target of any Sanctions Laws and Regulations or Anti-Terrorism Laws. 
 ARTICLE V 

FINANCIAL COVENANT 
 The Borrower
(and, to the extent set forth in any other Loan Document, each other Loan Party) agrees solely with the Lenders holding Pro Rata Loans and Pro Rata Commitments, the L/C Issuers and the Pro Rata Administrative Agent to the following, as long as any
Obligation or any Commitment remains outstanding under (or in respect of) the Pro Rata Loans and the Pro Rata Commitments: 

Section 5.1 Maximum Consolidated Secured Leverage Ratio. The Borrower shall not have, on the last day of any Fiscal
Quarter, a Consolidated Secured Leverage Ratio of greater than 4.50:1.00. 
 ARTICLE VI 

REPORTING COVENANTS 
 The Borrower
(and, to the extent set forth in any other Loan Document, each other Loan Party) agrees with the Lenders, the L/C Issuers, the Collateral Agent and the Administrative Agents to each of the following, as long as any Obligation, Letter of Credit or
any Commitment remains outstanding: 
 Section 6.1 Financial Statements. The Borrower shall deliver to the Administrative
Agents each of the following: 
 (a) Quarterly Reports. As soon as available, and in any event within 45 days after the end of each
of the first three Fiscal Quarters of each Fiscal Year, the Consolidated unaudited balance sheet of the Borrower as of the close of such Fiscal Quarter and related Consolidated statements of income and cash flow for such Fiscal Quarter and that
portion of the Fiscal Year ending as of the close of such Fiscal Quarter, setting forth in comparative form the figures for the corresponding period in the prior Fiscal Year and the figures contained in the latest Projections, in each case certified
by a Responsible Officer of the Borrower as fairly presenting in all material respects the Consolidated financial position, results of operations and cash flow of the Borrower as at the dates indicated and for the periods indicated in accordance
with GAAP (subject to the absence of footnote disclosure and normal year-end audit adjustments). 
 (b) Annual Reports. As soon as
available, and in any event within 90 days after the end of each Fiscal Year, the Consolidated balance sheet of the Borrower as of the end of such year and related Consolidated statements of income, stockholders’ equity and cash flow for such
Fiscal Year, each prepared in accordance with GAAP, together with a certification by the Group Members’ Accountants that such Consolidated Financial Statements fairly present in all material respects the Consolidated financial position, results
of operations and cash flow of the Borrower as at the dates indicated and for the periods indicated therein in accordance with GAAP without qualification as to the scope of the audit or as to going concern and without any other similar qualification
(except as may be required as a result of (x) a prospective Event of Default with respect to a breach of the financial covenant contained in Article V or (y) the impending maturity of any Facility). 

  
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 (c) Compliance Certificate. Together with each delivery of any Financial Statement
pursuant to clause (a) or (b) above, a Compliance Certificate duly executed by a Responsible Officer of the Borrower that, among other things, (i) demonstrates compliance with the financial covenant contained in
Article V, (ii) if delivered together with any Financial Statement pursuant to clause (b) above (commencing in respect of the Fiscal Year ending December 31, 2016), shows in reasonable detail the calculations used
in determining (x) Excess Cash Flow, (y) the amount of the payment required by Section 2.8(a) and (z) the Available Amount and any usage thereof; provided that the calculation set forth in this clause
(z) shall also be delivered at such other times (but not more than quarterly) as may be requested by any Administrative Agent, and (iii) states that no Default or Event of Default is continuing as of the date of delivery of such
Compliance Certificate or, if a Default or an Event of Default is continuing, states the nature thereof and the action that the Borrower proposes to take with respect thereto. 

(d) Corporate Chart. Together with delivery of any Financial Statement pursuant to clause (b) above, each in form and
substance reasonably satisfactory to the Administrative Agents, a certificate by a Responsible Officer of the Borrower that the Corporate Chart attached thereto (or the last Corporate Chart delivered pursuant to this clause (d)) is correct
and complete as of the date of such Compliance Certificate. 
 (e) Additional Projections. As soon as available and in any event not
later than 75 days after the end of each Fiscal Year, any significant revisions to, (i) the annual business plan of the Group Members for the Fiscal Year next succeeding such Fiscal Year and (ii) a forecast prepared by management of the
Borrower for each Fiscal Quarter in such next succeeding Fiscal Year, including in such forecast (x) a projected year-end Consolidated balance sheet, income statement and statement of cash flows, (y) a statement of all of the material
assumptions on which such forecasts are based and (z) substantially the same type of financial information as that contained in the Initial Projections. 

(f) Management Discussion and Analysis. To the extent not included in the Borrower’s public filings with the SEC, together with
each delivery of any Financial Statement pursuant to clause (a) or (b) above, a management’s discussion and analysis of the financial condition and results of operations of the Group Members for the portion of the Fiscal
Year then elapsed and discussing the reasons for any significant variations from the Projections for such period and the figures for the corresponding period in the previous Fiscal Year. 

(g) Intercompany Loan Balances. Together with each delivery of any Financial Statements pursuant to clause (b) above, a
summary of the outstanding balances of all intercompany Indebtedness as of the last day of the Fiscal Year covered by such Financial Statement, certified as complete and correct by a Responsible Officer of the Borrower as part of the Compliance
Certificate delivered in connection with such Financial Statements. 
 (h) Audit Reports, Management Letters, Etc. Together with each
delivery of any Financial Statements for any Fiscal Year pursuant to clause (b) above, copies of each management letter, audit report or similar letter or report received by any Group Member from any independent registered certified
public accountant (including the Group Members’ Accountants) in connection with such Financial Statements or any audit thereof, each certified to be complete and correct copies by a Responsible Officer of the Borrower as part of the Compliance
Certificate delivered in connection with such Financial Statements. 

  
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 Section 6.2 Other Events. The Borrower shall give the Administrative Agents
notice of each of the following (which may be made by telephone if promptly confirmed in writing) promptly after any Responsible Officer of any Group Member knows or has reason to know of it: (a) any Default or Event of Default, (b) any
event (other than any event involving loss or damage to property) reasonably expected to result in a mandatory payment of the Obligations pursuant to Section 2.8, stating the material terms and conditions of such transaction and
estimating the Net Cash Proceeds thereof, (c) the initiation by the Borrower or any Subsidiary thereof of any product recall or correction that is required to be reported to any Governmental Authority that, either individually or in the
aggregate, could reasonably be expected to have a Material Adverse Effect, (d) the commencement of, or any material adverse developments in, any action, investigation, suit, proceeding, audit, claim, demand, order or dispute with, by or before
any Governmental Authority affecting any Group Member or any property of any Group Member that (i) seeks material injunctive or similar relief against any Group Members that, either individually or in the aggregate, could reasonably be expected
to have a Material Adverse Effect, (ii) in the reasonable judgment of the Borrower, exposes any Group Member to liability in an aggregate amount in excess of $20,000,000 or (iii) has a reasonable possibility of being determined adversely
to any Group Member and if so adversely determined could reasonably be expected to have, either individually or in the aggregate, a Material Adverse Effect and (e) the acquisition of any material real property by any Loan Party. 

Section 6.3 Copies of Notices and Reports. The Borrower shall promptly deliver to the Administrative Agents copies of each
of the following: (a) except to the extent publicly filed, all reports that the Borrower transmits to its security holders generally, and (b) except to the extent publicly filed, all material documents that any Group Member files with the
SEC, the National Association of Securities Dealers, Inc., any securities exchange or any Governmental Authority exercising similar functions. 

Section 6.4 Taxes. Promptly after any Responsible Officer of any Group Member obtains knowledge of it, the Borrower shall
give the Administrative Agents notice (which may be made by telephone if promptly confirmed in writing) of the receipt of any written request directed to any Tax Affiliate to make any adjustment under Section 481(a) of the Code by reason of a
change in accounting method or otherwise, which, in each of the foregoing cases, could reasonably be expected to have, either individually or in the aggregate, a Material Adverse Effect. 

Section 6.5 Labor Matters. The Borrower shall give the Administrative Agents notice of each of the following (which may be
made by telephone if promptly confirmed in writing), promptly after, and in any event within 30 days after any Responsible Officer of any Group Member obtains knowledge of: (a) the commencement of any labor dispute to which any Group Member is
or may become a party, including any strikes, lockouts or other disputes relating to any of such Person’s plants and other facilities and (b) the incurrence by any Group Member of any Worker Adjustment and Retraining Notification Act or
related or similar liability incurred with respect to the closing of any plant or other facility of any such Person (other than, in the case of clause (a) or clause (b) above, those that would not, either individually or in
the aggregate, have a Material Adverse Effect). 
 Section 6.6 ERISA Matters. The Borrower shall give the Administrative
Agents (a) on or prior to any filing by any ERISA Affiliate of any notice of intent to terminate any Title IV 

  
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Plan, a copy of such notice and (b) promptly, and in any event within 10 days, after any Responsible Officer of any ERISA Affiliate knows or has reason to know thereof that (i) a
request for a minimum funding waiver under Section 412 of the Code has been filed with respect to any Title IV Plan or Multiemployer Plan, a notice (which may be made by telephone if promptly confirmed in writing) describing such waiver request
and any action that any ERISA Affiliate proposes to take with respect thereto, together with a copy of any notice filed with the PBGC or the IRS pertaining thereto or (ii) any ERISA Event has occurred, a notice (which may be made by telephone
if promptly confirmed in writing) of such ERISA Event, together with a statement of the Responsible Officer setting forth the details of such ERISA Event and the action which the ERISA Affiliates propose to take with respect thereto, in each case in
respect of the preceding clauses (a) and (b), to the extent that any such event could reasonably be expected to have, either individually or in the aggregate, a Material Adverse Effect. 

Section 6.7 Environmental Matters. The Borrower shall provide the Administrative Agents notice of each of the following (which
may be made by telephone if promptly confirmed in writing) promptly after any Responsible Officer of any Group Member obtains knowledge of (and, upon reasonable request of either Administrative Agent, documents and information in connection
therewith): (i)(A) unpermitted Releases, or (B) the receipt by any Group Member of any notice of violation of or potential liability or similar notice under, or the existence of any condition that could reasonably be expected to result in
violations of or liabilities under, any Environmental Law, or (C) the commencement of, or any material change to, any action, investigation, suit, proceeding, audit, claim, demand, dispute alleging a violation of or liability under any
Environmental Law, that, for each of clauses (A), (B) and (C) above (and, in the case of clause (C), if adversely determined), in the aggregate for each such clause, could reasonably be expected to have,
either individually or in the aggregate, a Material Adverse Effect, and (ii) the receipt by any Group Member of notification that any property of any Group Member is subject to any Lien in favor of any Governmental Authority securing, in whole
or in part, Environmental Liabilities that could reasonably be expected to have, either individually or in the aggregate, a Material Adverse Effect. 

Section 6.8 Other Information. The Borrower shall provide the Administrative Agents with such other documents and
information with respect to the business, property, condition (financial or otherwise), legal, financial or corporate or similar affairs or operations (including tax, insurance and environmental matters) of any Group Member as either Administrative
Agent or any Lender through either Administrative Agent may from time to time reasonably request. 
 Section 6.9 Delivery of
Information to Lenders. The Applicable Administrative Agent shall provide to each Lender for which it is acting as an Administrative Agent copies of all documents and information delivered by the Borrower to the Applicable Administrative Agent
pursuant to this Article VI upon delivery of such documents and information to the Applicable Administrative Agent (it being understood that the foregoing is the obligation of the Applicable Administrative Agent and not the obligation of the
Borrower). 
 Section 6.10 Annual Lender Call. At the request of either Administrative Agent, the Borrower will within 10
days after the date of the delivery (or, if later, required delivery) of the annual financial information pursuant to Section 6.1(b), hold a conference call or teleconference, at a time selected by the Borrower and reasonably acceptable
to the Administrative Agents, with all of the Lenders that choose to participate, to review the financial results of such Fiscal Year and the financial condition of the Borrower and its Subsidiaries and the additional projections presented for the
current Fiscal Year of the Borrower and its Subsidiaries. 

  
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 Section 6.11 Patriot Act. Promptly following either Administrative
Agent’s or any Lender’s request therefor, the Borrower shall provide all documentation and other information that such Administrative Agent or such Lender (through either Administrative Agent) reasonably requests in order to comply with
its ongoing obligations under the applicable “know your customer” and anti-money laundering rules and regulations, including the Patriot Act. 

ARTICLE VII 
 AFFIRMATIVE COVENANTS

 The Borrower (and, to the extent set forth in any other Loan Document, each other Loan Party) agrees with the Lenders, the L/C Issuers,
the Collateral Agent and the Administrative Agents to each of the following, as long as any Obligation, Letter of Credit or any Commitment remains outstanding: 

Section 7.1 Maintenance of Corporate Existence. Each Group Member shall (a) preserve and maintain its legal existence,
except in the consummation of transactions expressly permitted by Sections 8.4 and 8.7, and (b) preserve and maintain its rights (charter and statutory), privileges, franchises and Permits necessary or desirable in the
conduct of its business, except, in the case of this clause (b), where the failure to do so would not, in the aggregate, have a Material Adverse Effect. 

Section 7.2 Compliance with Laws, Etc. (a) Each Group Member shall comply with all applicable Requirements of Law
(including all Healthcare Laws), Contractual Obligations, Constituent Documents and Permits, except for such failures to comply that would not, in the aggregate, have a Material Adverse Effect. 

(b) Each Group Member shall comply with all applicable Anti-Money Laundering Laws, Anti-Terrorism Laws, Anti-Corruption Laws and Sanctions
Laws and Regulations, except to the extent that any non-compliance could not reasonably be expected to have, individually or in the aggregate, a Material Adverse Effect. 

(c) The Borrower and its Subsidiaries shall implement and maintain in effect policies and procedures which are designed to ensure compliance
in all material respects by the Borrower, each other Group Member and their respective directors, Affiliates, officers, employees and agents with Anti-Money Laundering Laws, Anti-Corruption Laws, Anti-Terrorism Laws and applicable Sanctions Laws and
Regulations. 
 Section 7.3 Payment of Obligations. Each Group Member shall pay or discharge before they become
delinquent (a) all material claims, taxes, assessments, charges and levies imposed by any Governmental Authority and (b) all other lawful claims that if unpaid would, by the operation of applicable Requirements of Law, become a Lien
(other than a Lien permitted by paragraphs (a) and (d) of the definition of Customary Permitted Liens) upon any property of any Group Member, except, (x) in the case of each of clauses (a) and (b) above,
for those whose amount or validity is being contested in good faith by proper proceedings diligently conducted and for which adequate reserves are maintained on the books of the appropriate Group Member in accordance with GAAP, and (y) in the
case of clause (a) above, any such item the non-payment or non-discharge of which could not reasonably be expected to have, individually or in the aggregate, a Material Adverse Effect. 

  
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 Section 7.4 Maintenance of Property. Each Group Member shall maintain and
preserve (a) in good working order and condition all of its property necessary in the conduct of its business and (b) all rights, permits, licenses, approvals and privileges (including all Permits and its registered Intellectual Property)
necessary, used or useful in the conduct of its business (whether for the ownership, lease, sublease or other operation or occupation of property or otherwise), and shall make all necessary or appropriate filings with, and give all required notices
to, Governmental Authorities, except for such failures to maintain and preserve the items set forth in clauses (a) and (b) above that would not, either individually or in the aggregate, have a Material Adverse Effect. Each
Group Member shall perform all obligations under any Contractual Obligation to which such Loan Party or any of its Subsidiaries is bound, or to which it or any of its properties is subject, except where the failure to perform would not have, either
individually or in the aggregate, a Material Adverse Effect. 
 Section 7.5 Maintenance of Insurance. Each Group Member
shall (a) maintain or cause to be maintained in full force and effect all policies of insurance of any kind with respect to the property and businesses of the Group Members (including policies of life, fire, theft, product liability, public
liability, property damage, other casualty, employee fidelity, workers’ compensation, business interruption and employee health and welfare insurance) with financially sound and reputable insurance companies or associations (in each case that
are not Affiliates of the Borrower) of a nature and providing such coverage as is sufficient and as is customarily carried by businesses of the size and character of the business of the Group Members and (b) cause all such insurance relating to
any property or business of any Loan Party to name the Collateral Agent on behalf of the Secured Parties as additional insured or loss payee, as appropriate (except in the case of director and officer liability policies, employee fidelity policies,
workers compensation policies, employee health and welfare policies, kidnap and ransom policies, theft policies, terrorism or similar policies), and use commercially reasonable efforts to provide that no cancellation, material addition in amount or
material change in coverage shall be effective until after 30 days’ notice thereof to the Collateral Agent. 
 Section 7.6
Keeping of Books. The Group Members shall keep proper books of record and account, in which, in all material respects, full, true and correct entries shall be made in accordance with GAAP and all other applicable Requirements of Law of all
financial transactions and the assets and business of each Group Member. 
 Section 7.7 Access to Books and Property.
Each Group Member shall permit the Administrative Agents, the Lenders and any Related Person of any of them, as often as reasonably requested, at any reasonable time during normal business hours and with reasonable advance notice (except that,
during the continuance of an Event of Default, no such notice shall be required) to (a) visit and inspect the property of each Group Member and examine and make copies of and abstracts from, the corporate (and similar), financial, operating and
other books and records of each Group Member, (b) discuss the affairs, finances and accounts of each Group Member with any officer or director of any Group Member and (c) communicate directly with any registered certified public
accountants (including the Group Members’ Accountants) of any Group Member. Each Group Member shall authorize their respective registered certified public accountants (including the Group Members’ Accountants) to communicate directly with
the Administrative Agents, the Lenders and their Related Persons and to disclose to the Administrative Agents, the Lenders and their Related Persons all financial statements and other documents and information as they might have and as either
Administrative Agent or any Lender reasonably requests with respect to any Group Member. 

  
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 Section 7.8 Environmental. Each Group Member shall comply with, and maintain
its real property, whether owned, leased, subleased or otherwise operated or occupied, in compliance with, all applicable Environmental Laws (including by (x) ensuring that there are no Releases of any Hazardous Material at, to or from any real
property owned, leased, subleased or otherwise operated or occupied by any Group Member that would violate any Environmental Law, form the basis for any Environmental Liabilities or otherwise adversely affect the value or marketability of any real
property (whether or not owned by any Group Member) and (y) implementing any Remedial Action necessary to achieve such compliance or that is required by orders and directives of any Governmental Authority), except, in each case, for failures to
comply that would not, either individually or in the aggregate, have a Material Adverse Effect. Without limiting the foregoing, if an Event of Default is continuing or if either Administrative Agent at any time has a reasonable basis to believe that
there exist violations of Environmental Laws by any Group Member or that there exist any Environmental Liabilities, in each case, that would have, either individually or in the aggregate, a Material Adverse Effect, then each Group Member shall,
promptly upon receipt of request from either Administrative Agent, cause the performance of, and allow the Administrative Agents and their respective Related Persons access to such real property for the purpose of conducting, such environmental
audits and assessments, including subsurface sampling of soil and groundwater, and cause the preparation of such reports, in each case as either Administrative Agent may from time to time reasonably request. Such audits, assessments and reports, to
the extent not conducted by the Administrative Agents or any of their respective Related Persons, shall be conducted and prepared by reputable environmental consulting firms reasonably acceptable to the Administrative Agents and shall be in form and
substance reasonably acceptable to the Administrative Agents. 
 Section 7.9 Use of Proceeds. The Borrower will use the
proceeds of the Loans and the Letters of Credit only as provided in Section 4.19. 
 Section 7.10 Additional
Collateral and Guaranties. To the extent not delivered to the Collateral Agent on or before the Closing Date (including in respect of after-acquired property and Persons that become Subsidiaries of any Loan Party after the Closing Date) and
except to the extent otherwise expressly provided under Section 7.13, each Loan Party shall, promptly (and, with respect to any Permitted Acquisition, within 45 days (or, in the case of clause (c) below, 90 days) of the
consummation thereof or (in either case) such longer period of time agreed to by the Collateral Agent), do each of the following, unless otherwise agreed by the Collateral Agent: 

(a) deliver to the Collateral Agent such modifications to the terms of the Loan Documents (or, to the extent applicable as determined by the
Collateral Agent, such other documents), in each case in form and substance reasonably satisfactory to the Collateral Agent and as the Collateral Agent deems necessary or advisable in order to ensure the following: 

(i) (A) each Subsidiary of any Loan Party shall guaranty, as primary obligor and not as surety, the payment of the Obligations
of the Borrower on the terms set forth in the Guaranty and Security Agreement; and 
 (ii) each Loan Party (including any
Person required to become a Guarantor pursuant to clause (i) above) shall effectively grant to the Collateral Agent, for the benefit of the Secured Parties, a valid and enforceable security interest in all of its

  
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property, including all of its Stock and Stock Equivalents and other Securities, as security for the Obligations of such Loan Party (excluding any Excluded Property, as defined in the Guaranty
and Security Agreement) on the terms set forth in the Guaranty and Security Agreement; 
 provided, however, that (A) unless the Borrower
and the Collateral Agent otherwise agree, in no event shall (x) any Excluded Foreign Subsidiary be required to guaranty the payment of any Obligation, (y) the Loan Parties, individually or collectively, be required to pledge in excess of
65% of the outstanding Voting Stock of any Excluded Foreign Subsidiary (and subject to clause (z) hereafter) or (z) a security interest be required to be granted on any property of any Excluded Foreign Subsidiary as security for any
Obligation, (B) no Unrestricted Subsidiary (so long as same remains an Unrestricted Subsidiary) shall be required to guaranty the payment of any Obligation or grant a security interest on any of its properties and (C) unless the Borrower
otherwise elects, no Immaterial Subsidiary (so long as same remains an Immaterial Subsidiary and taking into account the proviso to the definition of “Material Subsidiary” contained herein) acquired or formed after the Closing Date shall
be required to guaranty the payment of any Obligation or grant a security interest in any of its properties unless such Subsidiary provides a guarantee in respect of any Indebtedness incurred under the Existing Notes Indentures, any Permitted
Additional Debt Document, any Permitted Acquisition Debt Document or any Permitted Refinancing of any of the foregoing; 
 (b) deliver to
the Collateral Agent all documents representing all Stock, Stock Equivalents, other Securities, chattel paper and instruments pledged pursuant to the documents delivered pursuant to clause (a) above, together with undated powers or
endorsements duly executed in blank; 
 (c) upon request of either Administrative Agent, deliver to the Collateral Agent a Mortgage on any
real property owned by any Loan Party having a fair market value in excess of $15,000,000, together with all Mortgage Supporting Documents reasonably requested by the Collateral Agent relating thereto (or, if such real property is located in a
jurisdiction outside the United States, similar documents reasonably deemed appropriate by the Collateral Agent to obtain, to the extent possible, the equivalent in such jurisdiction of a first-priority mortgage on such real property); 

(d) subject to the terms of the Guaranty and Security Agreement, take all other actions necessary or advisable to ensure the validity or
continuing validity of any guaranty for any Obligation or any Lien securing any Obligation, to perfect, maintain, evidence or enforce any Lien securing any Obligation or to ensure such Lien has the same priority as that of the Liens on similar
Collateral set forth in the Loan Documents executed on the Closing Date (or, for Collateral located outside the United States, a similar priority reasonably acceptable to the Collateral Agent), including (x) the filing of UCC financing
statements in such jurisdictions as may be required by the Loan Documents or applicable Requirements of Law or as the Collateral Agent may otherwise reasonably request, and (y) with respect to the outstanding Voting Stock of any Excluded
Foreign Subsidiary required to be pledged hereunder (which shall specifically exclude Orgenics Ltd. and Orgenics International Holdings, B.V. for so long as the terms of the Indebtedness of any such Group Member prohibit such pledge or would give
rise to an event of default thereunder), upon request of the Collateral Agent, pledge agreements and similar documents deemed appropriate by the Collateral Agent to obtain and perfect a security interest or the equivalent under the laws of the
jurisdiction of organization of such Excluded Foreign Subsidiary, in such Voting Stock; provided that the documents required under this clause (y) shall 

  
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be required only with respect to any Excluded Foreign Subsidiary which generates gross revenues on a consolidated basis with its Subsidiaries in any Fiscal Year of greater than $25,000,000 (or
such higher amount as may be otherwise agreed to by the Collateral Agent); 
 (e) use commercially reasonable efforts to deliver to the
Collateral Agent a landlord’s agreement or bailee letter, as applicable, from the lessor of each leased property or bailee with respect to any warehouse, processor or converter facility or other location where Collateral with a value in excess
of $10,000,000 is stored or located, unless otherwise consented to by the Collateral Agent, which agreement or letter shall contain a customary waiver or subordination of all Liens or claims that the landlord or bailee may assert against the
Collateral at that location and shall otherwise be reasonably satisfactory in form and substance to the Collateral Agent; and 
 (f) deliver
to the Administrative Agents, the Collateral Agent and the Lenders legal opinions relating to the matters described in this Section 7.10, which opinions shall be as reasonably required by, and in form and substance and from counsel
reasonably satisfactory to, the Collateral Agent. 
 Notwithstanding anything to the contrary contained herein or in any other Loan Document, (i) no
Loan Party shall be required to pledge the Stock or Stock Equivalents or other equity Securities of any Unrestricted Subsidiary and such Stock or Stock Equivalents or other equity Securities shall not constitute Collateral, and (ii) in no event
shall any Unrestricted Subsidiary be required to guaranty any Obligations or enter into any Loan Document. 
 Section 7.11
Deposit Accounts; Securities Accounts and Cash Collateral Accounts. (a) Each Loan Party shall, unless otherwise consented to by the Collateral Agent and except to the extent otherwise expressly provided under Section 7.10 or
Section 7.13, deposit all of its cash and Cash Equivalents in deposit accounts that are Controlled Deposit Accounts or in securities accounts that are Controlled Securities Accounts; provided, however, that (i) each
Group Member may maintain zero-balance accounts that are not so controlled for the purpose of managing local disbursements and may maintain accounts that are not so controlled for: (A) payroll, (B) payroll taxes, (C) other employee
wage and benefit payments for the benefit of the Group Members’ salaried employees, and (D) withholding tax and other fiduciary accounts, and (ii) the foregoing requirements shall not apply to (x) cash and Cash Equivalents the
aggregate value of which does not exceed $5,000,000 and (y) cash and Cash Equivalents that are required under applicable foreign law (including to comply with (or is advisable to facilitate compliance with) any applicable foreign takeover
statutes) to be deposited by a Group Member in a non-controlled foreign bank account in connection with the consummation of a Permitted Acquisition or Designated Permitted Investment of any Person that is not a Domestic Person in advance of
completing such Permitted Acquisition or Designated Permitted Investment, provided that if after such cash or Cash Equivalents have been deposited, such Permitted Acquisition or Designated Permitted Investment is terminated or not otherwise
consummated for any reason, the applicable Group Member shall promptly re-transfer such cash to a Controlled Deposit Account or Controlled Securities Account otherwise in compliance with this Section 7.11. 

(b) The Collateral Agent shall not have any responsibility for, or bear any risk of loss of, any investment or income of any funds in any Cash
Collateral Account. From time to time after funds are deposited in any Cash Collateral Account, the Collateral Agent may apply funds then held in such Cash Collateral Account to the payment of Obligations in accordance with Section 2.12.
No Group Member and no Person claiming on behalf of or 

  
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through any Group Member shall have any right to demand payment of any funds held in any Cash Collateral Account at any time prior to the termination of all Commitments and the payment in full of
all Obligations and, in the case of L/C Cash Collateral Accounts, the termination of all outstanding Letters of Credit. 

Section 7.12 Credit Rating. The Borrower shall use its commercially reasonable efforts to maintain at all times
(i) monitored public debt ratings (of any level) from S&P and Moody’s in respect of the Facilities and (ii) a monitored public corporate rating and a monitored public corporate family rating (in each case, of any level) from
S&P and Moody’s. 
 Section 7.13 Post-closing Deliveries. The Borrower shall deliver to Administrative Agents or
the Collateral Agent, as applicable, in form and substance reasonably satisfactory to Administrative Agents, the items (or undertake the efforts) described on Schedule 7.13 on or before the dates specified with respect to such items and
efforts or such later dates as may be agreed to by Administrative Agents, in their sole discretion. 
 Section 7.14 Margin
Regulations. Except as provided in the second succeeding sentence, the Borrower shall take all actions so that at all times the fair market value of all Margin Stock owned by the Borrower and its Subsidiaries (other than Stock of the Borrower
held in treasury) shall not exceed $35,000,000. So long as the covenant contained in the immediately preceding sentence is complied with (and notwithstanding any provision to the contrary in any of the Loan Documents), all Margin Stock at any time
owned by the Borrower and its Subsidiaries will not constitute Collateral and no security interest shall be granted therein pursuant to any Loan Document. If at any time the fair market value of all Margin Stock owned by the Borrower and its
Subsidiaries (other than Stock of the Borrower held in treasury) exceeds $35,000,000, then (x) all Margin Stock in excess of $5,000,000 in the aggregate in fair market value that is owned by the Loan Parties (other than Stock of the Borrower
held in treasury) shall be pledged, and delivered for pledge, pursuant to the Guaranty and Security Agreement and (y) the Borrower will execute and deliver to the Lenders appropriate completed forms (including, without limitation, Forms G-3 and
U-1, as appropriate) establishing compliance with Regulations T, U and X. If at any time any Margin Stock is required to be pledged as a result of the provisions of the immediately preceding sentence, repayments of outstanding Obligations shall be
required, and the making of subsequent Loans and/or issuance of Letters of Credit shall be permitted, only in compliance with the applicable provisions of Regulations T, U and X of the Federal Reserve Board. 

Section 7.15 Designation of Subsidiaries. (a) The Borrower may at any time after the Closing Date designate any
Subsidiary as an Unrestricted Subsidiary; provided that (i) immediately before and after such designation, no Default or Event of Default then exists or would result therefrom, (ii) the Borrower shall be in compliance, on a Pro
Forma Basis, as of the last day of the Fiscal Quarter ended on or most recently prior to the date of the respective designation for which Financial Statements have been delivered hereunder, as if such designation had been made on the first day of
the four Fiscal Quarter period ended on the last day of such most recently ended Fiscal Quarter, with a Consolidated Secured Leverage Ratio of no greater than 4.00:1.00, (iii) such Unrestricted Subsidiary shall be capitalized (to the extent
capitalized by the Borrower or any of its Subsidiaries) solely through Investments as permitted by, and in compliance with, Sections 8.3(k) and (m), valued at their fair market value (as determined in good faith by the Borrower) at the
time of such designation, it being understood that, without duplication, any assets owned by such Unrestricted Subsidiary at the time of the initial designation thereof shall be treated as Investments pursuant to Sections 8.3(k) and/or
(m) (and 

  
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allocated between such Sections in a manner determined by the Borrower to the extent that any such Investment could otherwise be made in compliance with either such Section) and
valued at their fair market value (as determined in good faith by the Borrower, and taking appropriate account of the liabilities of such Unrestricted Subsidiary) at the time of such designation, (iv) such Subsidiary shall have been designated
as an “unrestricted subsidiary” (to the extent applicable) for purposes of the Existing Notes Indentures, any Permitted Refinancing thereof or any Permitted Additional Debt, (v) no Subsidiary may be designated as an Unrestricted
Subsidiary if such Subsidiary shall at any time own any Stock in, Indebtedness of, or have any Lien on any property of, the Borrower or any Subsidiary of the Borrower, other than another Unrestricted Subsidiary, (vi) except to the extent
permitted by Section 8.1(p), any Indebtedness of such Unrestricted Subsidiary is not recourse to the Borrower or any of its Subsidiaries (other than Unrestricted Subsidiaries) or to any of their respective assets, and (vii) the
Borrower shall have delivered to the Administrative Agents a certificate executed by a Responsible Officer of the Borrower certifying compliance with the requirements of preceding clauses (i) through (vi) and demonstrating
(in reasonable detail) the calculations required to establish compliance with preceding clauses (ii) and (iii). 
 (b)
The Borrower may designate any Unrestricted Subsidiary to be a Subsidiary for purposes of this Agreement and the other Loan Documents; provided that (i) no Default or Event of Default has occurred and is continuing or would result
therefrom, (ii) the Borrower shall be in compliance, on a Pro Forma Basis, as of the last day of the Fiscal Quarter ended on or most recently prior to the date of the respective designation for which Financial Statements have been delivered
hereunder, as if such designation had been made on the first day of the four Fiscal Quarter period ended on the last day of such most recently ended Fiscal Quarter, with the financial covenant set forth in Article V, (iii) any
Indebtedness of the applicable Unrestricted Subsidiary and any Liens encumbering its property existing at the time of such designation shall be deemed newly incurred or created, as applicable, at such time, (iv) at the time of such designation,
such Unrestricted Subsidiary shall be treated as a newly acquired or created Subsidiary for purposes of Sections 7.10 and 7.11 and the Borrower and the applicable Subsidiary shall comply with such Sections 7.10 and
7.11, as applicable, (v) at the time of such designation, the investment baskets under Sections 8.3(k) and/or (m) shall be replenished (but only to the extent that either such investment basket was utilized in making
an investment in an Unrestricted Subsidiary) by an aggregate amount (without duplication) equal to the lesser of (x) the fair market value (as determined in good faith by the Borrower, but taking appropriate account of the liabilities of such
Unrestricted Subsidiary) of the assets of such Unrestricted Subsidiary at such time (but, for this purpose, excluding the fair market value of the assets of any Subsidiary of such Unrestricted Subsidiary that is to remain an Unrestricted Subsidiary)
and (y) the aggregate amount of the Investments of the Borrower and its Subsidiaries theretofore made in such Unrestricted Subsidiary (including the amount by which either such investment basket was so utilized), and (vi) the Borrower
shall have delivered to the Administrative Agents a certificate executed by a Responsible Officer of the Borrower certifying compliance with the requirements of preceding clauses (i), (ii) and (iii) and demonstrating in
reasonable detail the replenishment amount referenced in preceding clause (v) and to what baskets such amount is properly allocated. 

(c) Notwithstanding the foregoing, any Unrestricted Subsidiary that has been re-designated a Subsidiary may not be subsequently re-designated
as an Unrestricted Subsidiary. 

  
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 ARTICLE VIII 

NEGATIVE COVENANTS 
 The Borrower
(and, to the extent set forth in any other Loan Document, each other Loan Party) agrees with the Lenders, the L/C Issuers, the Collateral Agent and the Administrative Agents to each of the following, as long as any Obligation, Letter of Credit or
any Commitment remains outstanding: 
 Section 8.1 Indebtedness. No Group Member shall, directly or indirectly, incur or
otherwise remain liable with respect to or responsible for, any Indebtedness except for the following: 
 (a) the Obligations, including any
Specified Refinancing Term Loans and Specified Refinancing Revolving Commitments incurred or issued in accordance with the terms of this Agreement; 

(b) Indebtedness existing on the date hereof and set forth on Schedule 8.1(b) (such Indebtedness described in this
clause (b) being “Existing Indebtedness”), together with any Permitted Refinancing of such Indebtedness permitted hereunder in reliance upon this clause (b); 

(c) Indebtedness consisting of Capitalized Lease Obligations (other than with respect to a lease entered into as part of a Sale and Leaseback
Transaction) and purchase money Indebtedness, in each case incurred by any Group Member to finance the acquisition, repair, improvement or construction of fixed or capital assets (including any associated software or other general intangibles) of
such Group Member, together with any Permitted Refinancing of any Indebtedness permitted hereunder in reliance upon this clause (c); provided, however, that (i) the aggregate outstanding principal amount of all such
Indebtedness (excluding any such Indebtedness that is Existing Indebtedness set forth on Schedule 8.1(b)) does not exceed $40,000,000 at any time and (ii) the principal amount of such Indebtedness does not exceed the cost of the property
so acquired or built or of such repairs or improvements financed, whether directly or through a Permitted Refinancing, with such Indebtedness; 

(d) Capitalized Lease Obligations arising under Sale and Leaseback Transactions (and any Permitted Refinancing thereof) permitted hereunder in
reliance upon Section 8.4(b)(ii) or Section 8.4(g); 
 (e) intercompany loans owing to any Group Member or any
Subsidiary of any Group Member and constituting Permitted Investments of such Group Member; 
 (f) obligations under Hedging Agreements
entered into for the sole purpose of hedging in the normal course of business; 
 (g) Guaranty Obligations of (i) any Loan Party with
respect to Indebtedness permitted hereunder of (x) any other Loan Party and (y) subject to the limitations set forth in Section 8.3 (including the final paragraph thereof), any Group Member that is not a Loan Party and
(ii) any Group Member that is not a Loan Party with respect to Indebtedness permitted hereunder of any Group Member; 

  
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 (h) unsecured Indebtedness of the Borrower owing under the Existing Notes pursuant to each of the
respective Existing Notes Indentures and any Permitted Refinancing of any such Indebtedness permitted hereunder in reliance upon this clause (h); 

(i) Permitted Acquisition Debt and any Permitted Refinancing of any such Indebtedness permitted hereunder in reliance upon this clause (i);

 (j) any unsecured Indebtedness of any Group Member; provided, however, that the aggregate outstanding principal amount of
all such unsecured Indebtedness (excluding any such Indebtedness that is Existing Indebtedness set forth on Schedule 8.1(b)) shall not exceed $50,000,000 at any time; 

(k) any Indebtedness of any Group Member that is not a Loan Party provided, however, that the aggregate outstanding principal
amount of all such Indebtedness (excluding any such Indebtedness that is Existing Indebtedness set forth on Schedule 8.1(b)) shall not exceed $50,000,000 at any time; 

(l) Indebtedness permitted under Section 8.2(e) (excluding any such Indebtedness that is Existing Indebtedness set forth on
Schedule 8.1(b)); 
 (m) Guaranty Obligations under or with respect to the P&G Holdings Guaranty, P&G JV Capital Call Obligations or
otherwise under the P&G JV Agreements; 
 (n) Permitted Additional Debt and any Permitted Refinancings of any such Indebtedness
permitted hereunder in reliance upon this clause (n); 
 (o) Indebtedness incurred by any Group Member constituting reimbursement
obligations with respect to letters of credit issued on behalf of a Group Member in the ordinary course of business; provided, however, that the aggregate outstanding principal amount of all such Indebtedness shall not exceed
$25,000,000 at any time; 
 (p) Guaranty Obligations in respect of Indebtedness of Unrestricted Subsidiaries in an aggregate outstanding
principal amount at any time not to exceed $25,000,000 (as reduced by any payments by a Group Member in respect of such Guaranty Obligations except to the extent that any such payment is reimbursed in cash to the respective Group Member by the
respective Unrestricted Subsidiary); and 
 (q) (i) Indebtedness of the Borrower, and guarantees thereof by the Guarantors, in respect of
the New 2023 Subordinated Notes so long as (x) substantially all of the proceeds thereof are used at or promptly after the time of incurrence to effect a satisfaction and discharge of the Existing 2018 Subordinated Notes in respect of the
redemption thereof pursuant to the terms of the Existing 2018 Subordinated Notes Indenture and to pay fees, premiums, costs and expenses relating thereto and to the issuance of the New 2023 Subordinated Notes and (y) the New 2023 Subordinated
Notes are issued within 30 days after the Closing Date, and (ii) any Permitted Refinancing of any such Indebtedness permitted hereunder in reliance upon this clause (q). 

Section 8.2 Liens. No Group Member shall incur, maintain or otherwise suffer to exist any Lien upon or with respect to any
of its property, whether now owned or hereafter acquired, except for the following: 
 (a) Liens created pursuant to any Loan Document; 

  
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 (b) Customary Permitted Liens of Group Members; 

(c) Liens existing on the date hereof and set forth on Schedule 8.2; 

(d) Liens on the property of any Group Member securing Indebtedness permitted hereunder in reliance upon
Section 8.1(c); provided, however, that (i) such Liens exist prior to the acquisition of, or attach substantially simultaneously with, or within 120 days after, the acquisition, repair, improvement or construction
of, such property financed, whether directly or through a Permitted Refinancing, by such Indebtedness and (ii) such Liens do not extend to any property of any Group Member other than the property (and proceeds thereof) acquired or built, or the
improvements or repairs, financed, whether directly or through a Permitted Refinancing, by such Indebtedness; 
 (e) Liens on any property
of any Loan Party securing any of their Indebtedness or their other liabilities; provided, however, that the aggregate outstanding principal amount of all such Indebtedness and other liabilities shall not exceed $20,000,000 at any
time; 
 (f) Liens on the property of any Group Member that is not a Loan Party securing Indebtedness permitted hereunder in reliance upon
Section 8.1(k); 
 (g) Liens on the property of any Loan Party securing Indebtedness incurred under any Permitted Additional
Debt Documents (including the documents relating to any Permitted Refinancing thereof) in reliance upon Section 8.1(n), so long as (x) the holders of the respective Indebtedness (or the respective agent or trustee on their behalf)
have entered into an intercreditor agreement in form and substance reasonably satisfactory to the Administrative Agents, and (y) such Liens are at all times subject to the terms and provisions of the intercreditor agreement referred to in
preceding clause (x); 
 (h) Liens on assets acquired in any Permitted Acquisition securing Permitted Acquisition Debt assumed in
connection with such Permitted Acquisition; provided that such Lien was not created in contemplation of such Permitted Acquisition and does not extend to or cover any other assets or property (other than the proceeds or products thereof);

 (i) Liens on the property of any Group Member subject to a Sale and Leaseback Transaction permitted under Section 8.4(b)(ii)
or (g) securing Indebtedness permitted hereunder in reliance upon Section 8.1(d); provided, however, that such Liens do not extend to any property of any Group Member other than the property (and proceeds
thereof) subject to such Sale and Leaseback Transaction; 
 (j) Liens on the property of any Group Member securing the Permitted Refinancing
of any Indebtedness secured by any Lien on such property permitted hereunder in reliance upon clause (c), (d), (h) or (i) above or this clause (j) without any increase in the property subject to such
Liens; 
 (k) Liens on any deposits of cash or Cash Equivalents of any Group Member securing Indebtedness permitted hereunder in reliance
upon Section 8.1(o), in an aggregate amount not exceeding $26,250,000 (or, if less, 105% of the amount of any such Indebtedness so incurred); 

  
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 (l) to the extent constituting a Lien, any Lien on cash and Cash Equivalents on deposit in one or
more foreign bank accounts referred to in Section 7.11(a)(ii)(y) in favor of the seller or sellers in or under the relevant Permitted Acquisition or Designated Permitted Investment; 

(m) so long as the applicable intercreditor agreement is then in effect and subject to the terms thereof, Liens on Collateral securing
obligations under the Specified Refinancing Term Loans and Specified Refinancing Revolving Commitments incurred in accordance with the terms of this Agreement; and 

(n) Liens on cash or Cash Equivalents deposited by any Group Member with a trustee, agent or other similar representative in favor of the
holders of Indebtedness of such Group Member pursuant to the defeasance or satisfaction and discharge terms under such Indebtedness to the extent that such Indebtedness, and the defeasance and satisfaction and discharge thereof, are permitted
hereunder. 
 Section 8.3 Investments. No Group Member shall make or maintain, directly or indirectly, any Investment
except for the following: 
 (a) Investments set forth on Schedule 8.3 and Investments set forth on Schedule 4.3(a); 

(b) Investments in cash and Cash Equivalents; 

(c) (i) endorsements for collection or deposit in the ordinary course of business consistent with past practice, (ii) extensions of trade
credit arising or acquired in the ordinary course of business and (iii) Investments received in settlements in the ordinary course of business of such extensions of trade credit; 

(d) Investments made as part of a Permitted Acquisition; 

(e) Investments by (i) any Loan Party in any other Loan Party, (ii) any Group Member that is not a Loan Party in any Group Member or
in any joint venture, and (iii) any Loan Party in any Group Member that is not a Loan Party or in any joint venture; provided, however, that any Investment consisting of loans or advances to any Loan Party pursuant to clause
(ii) above shall be subordinated in full to the payment of the Obligations of such Loan Party on terms and conditions reasonably satisfactory to the Administrative Agents; 

(f) loans or advances to employees of the Borrower or any of its Subsidiaries to finance travel, entertainment and relocation expenses and
other ordinary business purposes in the ordinary course of business; provided, however, that the aggregate outstanding principal amount of all loans and advances permitted pursuant to this clause (f) shall not exceed
$5,000,000 at any time; 
 (g) pledges and deposits made by a Group Member to the extent permitted under Section 8.2(b); 

(h) Hedging Agreements entered into by a Loan Party or any of its Subsidiaries to the extent permitted under Section 8.1(f); 

  
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 (i) Guaranty Obligations to the extent permitted under Section 8.1; 

(j) payments required under the P&G JV Capital Call Obligations to the P&G JV Companies in accordance with the P&G JV Agreements,
in an amount not to exceed $10,000,000 for any individual capital call at any time or $20,000,000 in the aggregate for all such capital calls during any Fiscal Year; provided that no Default or Event of Default exists or will result from the
making of any such payment and, after giving effect to such payment, the Loan Parties shall have unused and available Revolving Credit Commitments and available cash and Cash Equivalents on deposit to a Cash Collateral Account, a Controlled Deposit
Account or a Controlled Securities Account of at least $150,000,000 in the aggregate; 
 (k) any Investment by the Borrower or any of its
Subsidiaries; provided, however, that the aggregate outstanding amount of all such Investments shall not exceed $350,000,000 at any time; 

(l) any Restricted Payment permitted pursuant to Section 8.5; and 

(m) other Investments in an aggregate amount not to exceed the Available Amount as in effect immediately prior to the respective Investment,
so long as (i) no Default or Event of Default then exists or would result from such Investment and (ii) the Borrower shall be in compliance, on a Pro Forma Basis, with a Consolidated Secured Leverage Ratio of no greater than 4.00:1.00 as
of the last day of the last Fiscal Quarter for which Financial Statements have been delivered hereunder for the four Fiscal Quarter period ending on such day. 

Notwithstanding the foregoing, the sum, without duplication, of (x) the fair market value of all Permitted Acquisitions (or portions
thereof) and (y) the aggregate net amount of other Investments (or portions thereof) (which in the case of Investments that are intercompany loans shall mean the outstanding balance thereof), in each case, made or acquired after the Closing
Date (excluding, in each case, any Excluded Investments, as defined below) in, to or for the benefit of, or by, any Person that is not, or does not become after giving effect to such Permitted Acquisition or other Investment, a Loan Party (including
(subject to the foregoing) the amount of any Permitted Acquisition Consideration (or portion thereof) payable in respect of any Proposed Acquisition Target which will not constitute a Loan Party after giving effect to the applicable Permitted
Acquisition as reasonably determined by Administrative Agents) shall not exceed 15% of Total Assets in the aggregate after the Closing Date. For purposes of any determination under the immediately preceding sentence, (i) the fair market value
of any Permitted Acquisition or amount of any other Investment shall at all times be the original fair market value or amount thereof at the time of the making thereof (or, in the case of any Investment that is an intercompany loan, the outstanding
balance thereof), and (ii) no decrease in Total Assets following the time of the making of any Permitted Acquisition or Investment shall apply to such Permitted Acquisition or Investment or any previously made Permitted Acquisition or
Investment. As used herein “Excluded Investments” means collectively (i) Permitted Acquisitions and other Investments (or portions thereof) to the extent funded or made with the Net Cash Proceeds of (x) the issuance of
Stock or Stock Equivalents of the Borrower (other than Disqualified Stock) or (y) the issuance of Permitted Acquisition Debt or Permitted Additional Debt that is, in each case, Subordinated Debt, (ii) Permitted Acquisition Consideration
payable in (x) Stock or Stock Equivalents of the Borrower (other than Disqualified Stock) or (y) Permitted Acquisition Debt or Permitted Additional Debt that is, in each case, Subordinated Debt, (iii) Investments by a Group Member
which is not a Loan Party in any other Person and (iv) Investments permitted under Section 8.3(j). In the event that the Borrower or a Subsidiary 

  
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thereof consummates an Investment (or series of related Investments) pursuant to clause (k) or (m) above at a time when such Investment (or series or related Investments)
could not be classified as a Permitted Acquisition, the Borrower shall have the right, upon written notice to the Administrative Agents (which notice may be delivered concurrently with any notices or certificates delivered pursuant to the definition
of Permitted Acquisition), to later reclassify such Investment (or series of related Investments) as a Permitted Acquisition so long as such Investment (or series of related Investments) satisfies all of the applicable requirements of a Permitted
Acquisition at such time and the Borrower takes all actions in accordance with the terms of this Agreement that are applicable to Permitted Acquisitions. Upon any reclassification of an Investment (and series of related Investments) as a Permitted
Acquisition in accordance with the terms of the immediately preceding sentence, such Investment (and series of related Investments) will be deemed to have been made under clause (d) above and shall no longer be deemed to be outstanding
under clause (k) or (m) above, as the case may be, and the baskets under such clauses (k) and/or (m) shall be replenished by the amount of the prior usage thereof in respect of such Investment. 

Section 8.4 Asset Sales and Stock Issuances. No Group Member shall Sell any of its property (other than cash) or issue
shares of its own Stock, except for the following: 
 (a) (i) in each case to the extent entered into in the ordinary course of business for
fair market value, (A) Sales of Cash Equivalents or inventory, and (B) Sales of property that has become obsolete or worn out or is no longer used by or useful to the Group Members, (ii) non-exclusive licenses of Intellectual Property
in the ordinary course of its business, and (iii) Sales of property to participants in clinical trials or in connection with research projects, in each case in the ordinary course of business and in accordance with past practices; 

(b) (i) a true lease or sublease of real property in the ordinary course of business not constituting Indebtedness and not entered into as
part of a Sale and Leaseback Transaction and (ii) a Sale of property pursuant to a Sale and Leaseback Transaction; provided, however, that the aggregate fair market value (measured at the time of the applicable Sale) of all
property covered by any outstanding Sale and Leaseback Transaction at any time shall not exceed $40,000,000; 
 (c) (i) any Sale of any
property (other than their own Stock or Stock Equivalents) by any Group Member to any other Group Member to the extent any resulting Investment constitutes a Permitted Investment, (ii) any Restricted Payment by any Group Member permitted
pursuant to Section 8.5, (iii) any distribution by the Borrower of the proceeds of Restricted Payments from any other Group Member to the extent permitted by Section 8.5, and (iv) any Permitted Investment; 

(d) (i) any Sale or issuance by the Borrower of its own Stock or Stock Equivalents, (ii) any Sale or issuance by any directly-owned
Subsidiary of the Borrower of its own Stock to the Borrower, (iii) any Sale or issuance by any Subsidiary of the Borrower of its own Stock to any Loan Party, (iv) any Sale or issuance by any Subsidiary of the Borrower which is not a Loan
Party of its own Stock to any Subsidiary of the Borrower which is not a Loan Party and (v) to the extent necessary to satisfy any Requirement of Law in the jurisdiction of incorporation of any Subsidiary of the Borrower, any Sale or issuance by
such Subsidiary of its own Stock constituting directors’ qualifying shares or nominal holdings; 

  
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 (e) as long as no Default or Event of Default is continuing or would result therefrom, any Sale
of property (other than as part of a Sale and Leaseback Transaction) of, or Sale or issuance of its own Stock or Stock Equivalents by, any Group Member (other than the Borrower) for at least fair market value (as determined in good faith by the
Borrower) and, except for aggregate Sale consideration with a fair market value (as reasonably determined by the Borrower) of up to $25,000,000 in any Fiscal Year, payable at least 75% in cash or Cash Equivalents at or promptly after such sale or
issuance; provided, however, that the aggregate consideration received for all such Sales made pursuant to this clause (e) after the Closing Date shall not at any time exceed 10% of Total Assets (and for purposes of the
foregoing determination, no decrease in Total Assets following the time of any Sale shall apply to such Sale or any previous Sale); 
 (f)
as long as no Default or Event of Default is continuing or would result therefrom, (i) any Sale of property to the P&G Joint Venture required under P&G JV Agreements or (ii) any Sale of the Group Members’ equity interests in
the P&G Joint Venture pursuant to the P&G Call Option; 
 (g) as long as no Default or Event of Default is continuing or would
result therefrom, any Sale of real property (including as part of a Sale and Leaseback Transaction) for fair market value payable in cash upon such sale; provided, however, that the aggregate consideration received after the Closing
Date for all such Sales shall not exceed $200,000,000; 
 (h) so long as no Default or Event of Default is continuing or would result
therefrom, to the extent necessary to satisfy any Requirement of Law in any applicable jurisdiction in connection with a Permitted Acquisition, any Sale of assets so long as (w) such assets are sold, transferred or disposed of on or prior to
the date required by such Requirement of Law, (x) the Borrower or its respective Subsidiary receives at least fair market value (as determined in good faith by the Borrower) for such Sale, (y) the aggregate amount of the gross proceeds
from the sale of such assets shall not exceed 20% of the consolidated fair market value (as determined in good faith by the Borrower) of the respective Proposed Acquisition Target and (z) at least 75% of the consideration received by the
Borrower or such Subsidiary shall be in the form of cash or Cash Equivalents and shall be paid at or promptly after the time of closing of such Sale; and 

(i) the consummation of any Designated Sale so long as (x) no Default or Event of Default is continuing or would result therefrom,
(y) any such Designated Sale is for at least fair market value (as determined in good faith by the Borrower) and (z) substantially all of the purchase price consideration received by the Borrower or its applicable Subsidiary shall be in
the form of cash or Cash Equivalents and, other than in respect of post-closing adjustments relating to working capital, cash balances indebtedness and other specified liabilities and other similar adjustments, be paid at or promptly after the time
of the consummation of such Designated Sale. 
 Section 8.5 Restricted Payments. No Group Member shall, directly or
indirectly, declare, order, pay, make or set apart any sum for any Restricted Payment except for the following: 
 (a) (i) Restricted
Payments (A) by any Loan Party (other than the Borrower) to any other Loan Party and (B) by any Group Member that is not a Loan Party to any Group Member and (ii) dividends and distributions by any Subsidiary of the Borrower that is
not a Wholly Owned Subsidiary to any holder of its Stock, to the extent made to all such holders ratably according to their ownership interests in such Stock; 

  
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 (b) dividends and distributions declared and paid on Stock or Stock Equivalents of any Group
Member ratably to the holders thereof and payable only in Stock that is not Disqualified Stock of such Group Member (and cash payments in lieu of the issuance of fractional shares in connection therewith); 

(c) the redemption, purchase or other acquisition or retirement for value by the Borrower of its common Stock (or Stock Equivalents with
respect to its common Stock) (A) from any present or former employee, director or officer (or the assigns, estate, heirs or current or former spouses thereof) of any Group Member upon the death, disability or termination of employment of such
employee, director or officer; provided, however, that the amount of such cash payments paid in any Fiscal Year shall not exceed $15,000,000 in the aggregate or (B) from any other Person; provided, however, that the
amount of such cash payments paid in any Fiscal Year in reliance upon this clause (B) shall not exceed $15,000,000 in the aggregate, provided, further however, that no action that would otherwise be permitted hereunder in
reliance upon this clause (c) shall be permitted if a Default or an Event of Default is then continuing or would result therefrom; 

(d) (i) conversion, exchange or exercise of Stock or Stock Equivalents of the Borrower or convertible Indebtedness (including the Existing
2016 Subordinated Convertible Notes or any convertible Permitted Additional Debt) into or for Stock or Stock Equivalents of the Borrower (other than Disqualified Stock) (and cash payments in lieu of the issuance of fractional shares in connection
therewith) and (ii) any payment, redemption, purchase, defeasance or other satisfaction (or setting apart any property for any such purpose) in respect of (including Permitted Refinancings of) convertible Indebtedness not prohibited by
Section 8.6 or any subordination provisions with respect thereto; 
 (e) (i) so long as (x) no Default or Event of Default
exists at the time of payment thereof or would result therefrom and (y) the Borrower is in compliance, on a Pro Forma Basis, with the financial covenant set forth in Article V as of the last day of the last Fiscal Quarter for which
Financial Statements have been delivered hereunder for the four Fiscal Quarter period ending on such day, Permitted Stock Repurchases and (ii) any retirement, termination, defeasance or cancellation of any Stock or Stock Equivalents of any Loan
Party held in its treasury so long as no cash payment is made in respect thereof; 
 (f) so long as no Default or Event of Default exists at
the time of payment thereof or would result therefrom, payment by the Borrower of cash dividends on the Borrower’s common Stock or Preferred Stock to the holders thereof; provided, however, that the aggregate amount of all cash
dividends paid in any Fiscal Year in reliance upon this clause (f) shall not exceed $25,000,000; 
 (g) the Borrower may make
scheduled interest payments on its Junior Indebtedness in accordance with the terms thereof and may make other payments in respect thereof to the extent not prohibited by Section 8.6, in each case to the extent that such Junior
Indebtedness constitutes Stock Equivalents of the Borrower and any such payment in respect thereof is not otherwise prohibited by, or violates the terms of, any subordination provisions of such Junior Indebtedness; and 

  
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 (h) other Restricted Payments in an aggregate amount not to exceed the Available Amount as in
effect immediately prior to the respective Restricted Payment, so long as (i) no Default or Event of Default is continuing or would result from such Restricted Payment and (ii) the Borrower shall be in compliance, on a Pro Forma Basis,
with a Consolidated Secured Leverage Ratio of no greater than 4.00:1.00 as of the last day of the last Fiscal Quarter for which Financial Statements have been delivered hereunder for the four Fiscal Quarter period ending on such day. 

Section 8.6 Payments on Junior Indebtedness. No Group Member shall (x) prepay, purchase, redeem, repurchase, defease
or otherwise satisfy, in each case prior to any scheduled maturity or amortization thereof, any Junior Indebtedness or set apart any property for such purpose, whether directly or indirectly and whether to a sinking fund, a similar fund or
otherwise, or (y) make any payment in violation of any subordination terms of any Subordinated Debt (each of preceding clauses (x) and (y), a “Restricted Debt Payment”); provided, however, that
each Group Member may, to the extent otherwise permitted by the Loan Documents, do each of the following: 
 (a) prepay, purchase, redeem,
repurchase, defease or otherwise satisfy prior to any scheduled maturity or amortization thereof (or set apart any property for such purpose), or otherwise repay at any time and from time to time, up to $150,000,000 in aggregate principal amount
outstanding under the Existing 2016 Subordinated Convertible Notes (including in conjunction with any conversion, exchange or other transaction with respect thereto permitted under Section 8.6(b) and/or any refinancing thereof permitted
under Section 8.6(c)), together with (i) any applicable redemption, repurchase, prepayment, tender offer, conversion, exchange, make-whole or other similar premiums or payments in connection therewith (whether payable in cash,
Borrower common Stock or other consideration otherwise permitted hereunder) and (ii) any consent or similar fees relating to any amendments or other changes in the terms of the Existing 2016 Subordinated Convertible Notes in connection
therewith (or otherwise (A) defease or satisfy and discharge principal amounts outstanding thereunder in accordance with the terms of the Existing Notes Documents relating thereto or (B) deposit with the Collateral Agent cash as security
for the benefit of the Secured Parties as contemplated by Section 1.3(a) with respect to the Existing 2016 Subordinated Convertible Notes) so long as (i) the Borrower shall be in compliance, on a Pro Forma Basis, with the financial
covenant set forth in Article V as of the last day of the last Fiscal Quarter for which Financial Statements have been delivered hereunder for the four Fiscal Quarter period ending on such day (after giving effect to (x) such
Restricted Debt Payment, (y) such defeasance or satisfaction and discharge in accordance with the respective terms of the applicable Existing Notes Documents or (z) such deposit with the Collateral Agent of cash as security for the benefit
of the Secured Parties) and (ii) as of the date of (x) such Restricted Debt Payment, (y) such defeasance or satisfaction and discharge in accordance with the respective terms of the applicable Existing Notes Documents or (z) such
deposit with the Collateral Agent of cash as security for the benefit of the Secured Parties, and after giving effect thereto on such date, no Default or Event of Default shall be continuing; 

(b) make or offer to make (or give any notice in respect thereof) any voluntary or optional payment or prepayment on, or any redemption,
purchase, retirement, defeasance or acquisition of, or any prepayment, repurchase or redemption, retirement or defeasance as a result of any asset sale, change in control or similar event of, any Junior Indebtedness, in each case, by delivery of or
conversion into or exchange for, or, so long as no Default or Event of Default then exists or would result therefrom, out of the proceeds of a 

  
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substantially concurrent issuance or sale of, Stock or Stock Equivalents of the Borrower (other than Disqualified Stock and other than Stock or Stock Equivalents issued or sold to a Subsidiary)
(including cash payments in lieu of the issuance of fractional shares in connection therewith); 
 (c) so long as no Default or Event of
Default then exists or would result therefrom, refinance all or any portion of any Junior Indebtedness with the proceeds of, or by exchange into Indebtedness constituting, a Permitted Refinancing in respect thereof or an issuance of Permitted
Additional Debt, in each case in accordance with, and as permitted by the terms of, Section 8.1; 
 (d) so long as no Default or
Event of Default then exists or would result therefrom, the Borrower and its Subsidiaries may prepay, purchase, redeem, repurchase, defease, satisfy and discharge or otherwise satisfy prior to any scheduled maturity or amortization thereof any
Permitted Acquisition Debt under clause (a)(i) of the definition thereof (including any Permitted Refinancing thereof); 
 (e) make
regularly scheduled interest and amortization payments only as and when due (to the extent that such payments are not prohibited by or in violation of any applicable subordination terms thereof); and 

(f) prepay, purchase, redeem, repurchase, defease, satisfy and discharge or otherwise satisfy Junior Indebtedness in an aggregate amount not
to exceed the Available amount as in effect immediately prior to such Restricted Debt Payment, so long as (i) no Default or Event of Default is continuing or would result (ii) the Borrower shall be in compliance, on a Pro Forma Basis, with
a Consolidated Secured Leverage Ratio of no greater than 4.00:1.00 as of the last day of the last Fiscal Quarter for which Financial Statements have been delivered hereunder for the four Fiscal Quarter period ending on such day. 

Section 8.7 Fundamental Changes. No Group Member shall (a) merge, consolidate, dissolve or amalgamate with any Person,
(b) acquire all or substantially all of the Stock or Stock Equivalents of any Person or (c) acquire all or substantially all of the assets of any Person or all or substantially all of the assets constituting any line of business, division,
branch, operating division or other unit operation of any Person, in each case except for the following: (i) to consummate any Permitted Acquisition, (ii) to consummate any Investment permitted under Section 8.3(k) or
(m), (iii) any Sale permitted hereunder, (iv) the dissolution of the Inactive Subsidiaries, (v) the dissolution of Subsidiaries of the Borrower that are Wholly-Owned Subsidiaries so long as (x) the assets of such
Wholly-Owned Subsidiary are distributed or transferred solely to its direct parent company which is the Borrower or a Wholly-Owned Subsidiary of the Borrower and (y) in the case of a dissolution of a Wholly-Owned Subsidiary that is a Loan
Party, such direct parent company also shall be a Loan Party, (vi) the dissolution of Subsidiaries of the Borrower that are not Loan Parties so long as the assets of such Subsidiary are distributed or transferred solely to its equity holders
ratably according to their ownership interests in such Subsidiary, (vii) the merger, consolidation or amalgamation of any Subsidiary of the Borrower with or into the Borrower or any other Subsidiary of the Borrower and (viii) the merger,
consolidation or amalgamation of any Group Member (other than the Borrower) for the sole purpose, and with the sole material effect, of changing its State of organization within the United States; provided, however, that (A) in
the case of any merger, consolidation or amalgamation involving the Borrower, the Borrower shall be the surviving Person, (B) in the case of any merger, consolidation or amalgamation involving any other Loan Party, a Loan Party shall be the
surviving corporation and all actions required to maintain the perfection of the Lien of the 

  
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Collateral Agent on the Stock or property of such Loan Party shall have been made and (C) for the avoidance of doubt, in no event shall the Borrower’s jurisdiction of incorporation be
changed to a non-U.S. jurisdiction, whether as a result of a merger or otherwise. 
 Section 8.8 Change in Nature of
Business. (a) No Group Member shall carry on any business, operations or activities (whether directly, through a joint venture, in connection with a Permitted Acquisition or otherwise) substantially different from those carried on by the
Borrower and its Subsidiaries at the Closing Date and business, operations and activities reasonably related thereto. 
 (b) None of the
Inactive Subsidiaries shall engage in any material business, operations or activity, or hold any material amount of property, other than the following, (i) paying taxes and dividends permitted hereunder, (ii) holding directors’ and
shareholders’ meetings, preparing corporate and similar records and other activities required to maintain its separate corporate or other legal structure, (iii) preparing reports to, and preparing and making notices to and filings with,
Governmental Authorities and to its holders of Stock, (iv) defending or otherwise taking action deemed appropriate by such Inactive Subsidiary or any Group Member with respect to any liabilities of such Inactive Subsidiary, including any
litigation, action or proceeding, including as set forth in Schedule 4.7, and (v) such other business, operations and activities consented to by the Administrative Agents; provided that nothing herein shall prohibit any Inactive
Subsidiary from incurring or suffering to exist any Indebtedness or other liabilities or obligations permitted to be incurred by any other Loan Party under this Agreement so long as such Inactive Subsidiary remains a Guarantor under the Loan
Documents. 
 Section 8.9 Transactions with Affiliates. No Group Member shall, except as otherwise expressly permitted
herein or set forth on Schedule 8.9, enter into any other transaction directly or indirectly with, or for the benefit of, any Affiliate of the Borrower that is not a Loan Party (including Guaranty Obligations with respect to any obligation of
any such Affiliate), except for (a) transactions in the ordinary course of business on a basis no less favorable to such Group Member as would be obtained in a comparable arm’s length transaction with a Person not an Affiliate of the
Borrower, (b) Restricted Payments, the proceeds of which, if received by the Borrower, are used as permitted by Section 8.5, (c) reasonable salaries and other reasonable director or employee compensation to officers and
directors of any Group Member, (d)(i) any transaction with a P&G JV Company or any Subsidiary or member thereof pursuant to the P&G JV Agreements or (ii) other transactions with a P&G JV Company or any Subsidiary or member thereof
for the manufacturing, packaging, supply or distribution of products or materials, or the provision of other administrative or operational services (whether on a transitional or ongoing basis), solely with respect to the consumer diagnostic
business, so long as, with respect to this clause (ii), the Group Members’ charges for manufacturing such products is on a “cost-plus” basis, (e) any intercompany transaction among or between Group Members which are not
Loan Parties, (f) subject to any applicable limitations in Section 8.3 (including the final paragraph thereof), any Guaranty Obligations by a Loan Party of any obligations of a Group Member that is not a Loan Party which is
incurred in the ordinary course of business of such non-Loan Party, (g) any Group Member that is not a Loan Party may issue to any Loan Party any note evidencing an obligation of such non-Loan Party owing to such Loan Party
and (h) any Guaranty Obligations by a Group Member of any Indebtedness of an Unrestricted Subsidiary to the extent permitted by Section 8.1(p). 

Section 8.10 Third-Party Restrictions on Indebtedness, Liens, Investments or Restricted Payments. No Group Member shall
incur or otherwise suffer to exist or become 

  
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effective or remain liable on or responsible for any legally effective Contractual Obligation limiting the ability of (a) any Subsidiary of the Borrower to make Restricted Payments to, or
Investments in, or repay Indebtedness or otherwise Sell property to, any Group Member or (b) any Group Member to incur or suffer to exist any Lien upon any property of any Group Member, whether now owned or hereafter acquired, securing any of
its Obligations (including any “equal and ratable” clause and any similar Contractual Obligation requiring, when a Lien is granted on any property, another Lien to be granted on such property or any other property), except, for each of
clauses (a) and (b) above, (q) encumbrances or restrictions existing under or by reason of applicable law, (r) non-assignment provisions or other restrictions on transfer contained in any lease, license or other
contract, (s) restrictions on the transfer of assets imposed under any agreement to Sell such assets to any Person pending the closing of such Sale, (t) restrictions (other than a restriction referenced in clause (b) above that
would be applicable to any equity or other ownership interests that would be required to be pledged to secure any Obligations under the terms of the Loan Documents) under customary provisions in partnership agreements, limited liability company
organizational or governance documents, joint venture agreements, corporate charters, stockholders’ agreements, and other similar agreements and documents on the transfer of ownership interests in such partnership, limited liability company,
joint venture or similar Person, in each case, with respect to any Person that is not a Wholly Owned Subsidiary of the Borrower or a Guarantor, (u) encumbrances or restrictions pursuant to Contractual Obligations existing on the Closing Date
and encumbrances or restrictions pursuant to Contractual Obligations arising after the Closing Date that are, in the good faith judgment of the Borrower, not materially more restrictive, taken as a whole, with respect to any Group Member(s) than
those in effect on the Closing Date with respect to the relevant Group Member(s) (including any future Subsidiary) pursuant to agreements in effect on the Closing Date, (v) pursuant to the Loan Documents, (w) limitations on Liens on any
property whose acquisition, repair, improvement or construction is financed by purchase money Indebtedness, Capitalized Lease Obligations or Permitted Refinancings permitted hereunder in reliance upon Section 8.1(b), (c) or
(l) set forth in the Contractual Obligations governing such Indebtedness, Capitalized Lease Obligations, or Permitted Refinancing or Guaranty Obligations with respect thereto, (x) pursuant to the Existing Notes Indentures (including
the guarantees thereunder), any Permitted Additional Debt Document and any Permitted Refinancing of any of the foregoing, (y) encumbrances or restrictions pursuant to Contractual Obligations entered into after the Closing Date governing
Indebtedness permitted hereunder in reliance upon Section 8.1(k) and (z) encumbrances or restrictions pursuant to Contractual Obligations (i) governing Indebtedness of the type described in subclause (a)(ii) of the
definition of “Permitted Acquisition Debt” permitted hereunder in reliance upon Section 8.1(i), or (ii) entered into after the Closing Date governing Indebtedness permitted hereunder in reliance upon
Section 8.1(j) or Section 8.1(l), that, in the case of this clause (ii), are, in the good faith judgment of the Borrower, not materially more restrictive, taken as a whole, with respect to any Subsidiary than those in effect
on the Closing Date with respect to that Subsidiary (or any future Subsidiary) pursuant to this Agreement. 
 Section 8.11
Modification of Certain Documents. No Group Member shall do any of the following: 
 (a) waive or otherwise modify any term of, or
provide any consent under, any Constituent Document of, or otherwise change the capital structure of, any Group Member (including the terms of any of their outstanding Stock or Stock Equivalents), in each case except for those modifications,
consents and waivers that (x) do not elect, or permit the election, to treat the Stock or Stock Equivalents of any limited liability company (or similar entity) as certificated and (y) do not materially adversely affect the interests of
any Secured Party under the Loan Documents or in the Collateral; 

  
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 (b) waive or otherwise modify any term of (w) any Subordinated Debt, if in any case the
effect thereof on such Subordinated Debt is to (i) increase the interest rate, (ii) change the due dates for principal or interest, other than to extend such dates, (iii) modify any default or event of default in any material respect,
other than to delete it or make it less restrictive, (iv) add any material covenant with respect thereto, (v) modify any subordination provision (if applicable) in any manner adverse to the Lenders, (vi) modify any redemption or
prepayment provision in any material respect adverse to the Lenders or more burdensome on the Borrower or any of its Subsidiaries, other than to extend the dates therefor or to reduce the premiums or any other amounts payable in connection therewith
or (vii) materially increase any obligation of any Group Member or confer additional material rights to the holder of such Indebtedness in a manner adverse to any Group Member or any Secured Party (provided that these limitations shall
not restrict or prohibit any Permitted Refinancing of such Subordinated Debt to the extent provided for under Section 8.1 and in compliance with the terms of the definition of “Permitted Refinancing”), (x) any Permitted
Acquisition Debt (including any Permitted Refinancing thereof) to the extent that such Permitted Acquisition Debt (or such Permitted Refinancing thereof) in the amended or modified form would not be permitted to be incurred or issued at such time in
accordance with Section 8.1(i) and the definition thereof), (y) any Permitted Additional Debt or any Permitted Additional Debt Document relating thereto (including any Permitted Refinancing thereof) to the extent that such Permitted
Additional Debt or Permitted Additional Debt Document relating thereto (or such Permitted Refinancing thereof) in the amended or modified form would not be permitted to be incurred or issued at such time in accordance with Section 8.1(n)
and the definition thereof) or (z) without limiting the provisions of clause (w) above, any Existing Notes or any Existing Notes Documents (including any Permitted Refinancing thereof) in a manner that shortens the maturity date of
such Indebtedness or provides for a shorter Weighted Average Life to Maturity (provided that this clause (z) shall not restrict or prohibit any Permitted Refinancing of any Existing Notes to the extent provided for under
Section 8.1 and in compliance with the terms of the definition of “Permitted Refinancing”); provided that nothing in this clause (b) shall limit any transaction permitted by Section 8.6; 

(c) amend, or enter into supplementary agreements with respect to, the P&G JV Agreements in a manner which could reasonably be expected to
have a Material Adverse Effect without the prior written consent of Administrative Agents; provided that the Borrower shall provide the Administrative Agents with a copy of any such material amendment or supplementary agreement; and 

(d) permit any Indebtedness (other than (x) the Obligations (including any Specified Refinancing Term Loans and Specified Refinancing
Revolving Commitments incurred or issued in accordance with this Agreement and that rank pari passu in right of payment and security with the Loans) and (y) any Permitted Additional Debt that ranks pari passu in right of payment and security
with the Loans) to qualify as “Designated Senior Debt” or “Designated Senior Indebtedness”, as applicable, under each of the Existing Subordinated Notes Indentures or permit the Obligations to cease qualifying as “Designated
Senior Debt” or “Designated Senior Indebtedness”, as applicable, under each of the Existing Subordinated Notes Indentures, any Permitted Additional Debt Document that constitutes Subordinated Debt or any Permitted Refinancing thereof.

  
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 Section 8.12 Accounting Changes; Fiscal Year. No Group Member shall change its
(a) accounting treatment or reporting practices, except as required by GAAP or any Requirement of Law or (b) its fiscal year or its method for determining fiscal quarters or fiscal months. 

Section 8.13 Compliance with ERISA. No ERISA Affiliate shall cause or suffer to exist (a) any event that could result
in the imposition of a Lien with respect to any Title IV Plan or Multiemployer Plan or (b) any other ERISA Event, that would, in the aggregate, have a Material Adverse Effect. No Group Member shall cause or suffer to exist any event that could
result in the imposition of a Lien with respect to any Benefit Plan. 
 Section 8.14 Use of Proceeds. The Borrower will
not, and will not permit any Group Member to, use proceeds or Letters of Credit of any of the Facilities (i) for the purposes of financing the activities or business of, other transactions with, or investments in, any Designated Person or any
Person otherwise the target of Sanctions Laws and Regulations or Anti-Terrorism Laws or (ii) in contravention of any Anti-Money Laundering Laws, Anti-Corruption Laws, Sanctions Laws and Regulations or Anti-Terrorism Laws. 

ARTICLE IX 
 EVENTS OF DEFAULT 

Section 9.1 Definition. Each of the following shall be an Event of Default: 

(a) the Borrower shall fail to pay (i) any principal of any Loan or any L/C Reimbursement Obligation when the same becomes due and
payable or (ii) any interest on any Loan, any fee under any Loan Document or any other Obligation (other than those set forth in clause (i) above) and, in the case of this clause (ii), such non-payment continues for a period
of 5 Business Days after the due date therefor; or 
 (b) any representation, warranty or certification made or deemed made by or on
behalf of any Loan Party (or any Responsible Officer thereof) in any Loan Document shall prove to have been incorrect in any material respect when made or deemed made; or 

(c) any Loan Party shall fail to comply with (i) Section 2.20(a)(ii), any provision of Article V,
Section 6.2(a), 7.1(a), 7.9 or Article VIII or (ii) any other provision of any Loan Document if, in the case of this clause (ii), such failure shall remain unremedied for 30 days after the earlier of
(A) the date on which a Responsible Officer of the Borrower becomes aware of such failure and (B) the date on which notice thereof shall have been given to the Borrower by either Administrative Agent or the Required Lenders;
provided that an Event of Default under Article V shall not constitute an Event of Default for purposes of any Facility not entitled to the benefits of such Article V unless and until the Pro Rata Administrative Agent (with the
consent, or at the request, of the Required Pro Rata Lenders) has actually terminated the Pro Rata Commitments then in effect and declared all outstanding Pro Rata Loans to be immediately due and payable in accordance with this Agreement and such
declaration has not been rescinded on or before such date; or 
 (d) (i) any Group Member (other than an Immaterial Subsidiary) shall fail
to make any payment when due (after giving effect to any applicable grace or cure period) (whether due because of scheduled maturity, required prepayment provisions, acceleration, demand or otherwise) on any Indebtedness of any such Group Member
(other than the Obligations or any Hedging Agreement) and, in each case, such failure relates to Indebtedness having an aggregate 

  
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principal amount of $50,000,000 or more, (ii) any other event shall occur or condition shall exist under any Contractual Obligation relating to any such Indebtedness (after giving effect to
any applicable grace or cure period) if the effect of such event or condition is to accelerate, or to permit the acceleration of, the maturity of such Indebtedness or (iii) any such Indebtedness shall become or be declared to be due and
payable, or be required to be prepaid, redeemed, defeased or repurchased (other than by a regularly scheduled required prepayment), prior to the stated maturity thereof; or 

(e) (i) any Group Member (other than an Immaterial Subsidiary) shall generally not pay its debts as such debts become due, shall admit in
writing its inability to pay its debts generally or shall make a general assignment for the benefit of creditors, (ii) any proceeding shall be instituted by or against any such Group Member seeking to adjudicate it a bankrupt or insolvent or
seeking liquidation, winding up, reorganization, arrangement, adjustment, protection, relief, composition of it or its debts or any similar order, in each case under any Requirement of Law relating to bankruptcy, insolvency or reorganization or
relief of debtors, or seeking the entry of an order for relief or the appointment of a custodian, receiver, trustee, conservator, liquidating agent, liquidator, other similar official or other official with similar powers, in each case for it or for
any substantial part of its property and, in the case of any such proceedings instituted against (but not by or with the consent of) any Group Member (other than an Immaterial Subsidiary), either such proceedings shall remain undismissed or unstayed
for a period of 60 days or more or any action sought in such proceedings shall occur, or (iii) any Group Member (other than an Immaterial Subsidiary) shall take any corporate or similar action or any other action to authorize any action
described in clause (i) or (ii) above; or 
 (f) one or more judgments, orders or decrees (or other similar process)
shall be rendered against any Group Member (other than an Immaterial Subsidiary) (i)(A) in the case of money judgments, orders and decrees, involving an aggregate amount (excluding amounts adequately covered by insurance payable to any such Group
Member, to the extent the relevant insurer has not denied coverage therefor) of $50,000,000 or more or (B) otherwise, that would have, either individually or in the aggregate, a Material Adverse Effect and (ii)(A) enforcement proceedings shall
have been commenced by any creditor upon any such judgment, order or decree or (B) such judgment, order or decree shall not have been vacated or discharged for a period of 30 consecutive days and there shall not be in effect (by reason of a
pending appeal or otherwise) any stay of enforcement thereof; or 
 (g) except pursuant to a valid, binding and enforceable termination or
release permitted under the Loan Documents and executed by the Collateral Agent and/or the Administrative Agents or as otherwise expressly permitted under any Loan Document, (i) any provision of any Loan Document shall, at any time after the
delivery of such Loan Document, fail to be valid and binding on, or enforceable against, any Loan Party party thereto in any material respect, (ii) any Loan Document purporting to grant a Lien to secure any Obligation shall, at any time after
the delivery of such Loan Document, fail to create a valid and enforceable Lien on any Collateral (other than an immaterial portion thereof) purported to be covered thereby or such Lien shall fail or cease to be a perfected Lien with the priority
required in the relevant Loan Document or (iii) any subordination provision set forth in any Existing Subordinated Notes Indenture, any Permitted Additional Debt that constitutes Subordinated Debt with an aggregate principal amount of
$50,000,000 or more or any Permitted Refinancing of any of the foregoing shall, in whole or in part, terminate or otherwise fail or cease to be valid and binding on, or enforceable against any holder of the relevant Subordinated Debt (or any trustee
therefor), or any Group Member shall state in writing that any of the events described in clause (i), (ii) or (iii) above shall have occurred; or 

  
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 (h) there shall occur any Change of Control. 

Section 9.2 Remedies. During the continuance of any Event of Default, the Administrative Agents together may, and, at the
request of the Required Lenders, shall, in each case by notice to the Borrower and in addition to any other right or remedy provided under any Loan Document or by any applicable Requirement of Law, do each or any of the following: (a) declare
all or any portion of the Commitments terminated, whereupon the Commitments shall immediately be reduced by such portion or, in the case of a termination in whole, shall terminate together with any obligation any Lender may have hereunder to make
any Loan and any L/C Issuer may have hereunder to Issue any Letter of Credit, (b) declare immediately due and payable all or part of any Obligation (including any accrued but unpaid interest thereon), whereupon the same shall become immediately
due and payable, without presentment, demand, protest or further notice or other requirements of any kind, all of which are hereby expressly waived by the Borrower (and, to the extent provided in any other Loan Document, other Loan Parties);
provided, however, that, effective immediately upon the occurrence of any Event of Default specified in Section 9.1(e)(ii) with respect to the Borrower, (x) the Commitments of each Lender to make Loans and the
commitment of each L/C Issuer to Issue Letters of Credit shall each automatically be terminated and (y) each Obligation (including in each case any accrued all accrued but unpaid interest thereon) shall automatically become and be due and
payable, without presentment, demand, protest or further notice or other requirement of any kind, all of which are hereby expressly waived by the Borrower (and, to the extent provided in any other Loan Document, any other Loan Party), (c) take
the actions described in Section 9.3, and (d) exercise (and/or direct the Collateral Agent to exercise) any other remedies which may be available under the Loan Documents or applicable law. 

Notwithstanding anything to the contrary, if the only Events of Default then having occurred and continuing are pursuant to a failure to observe any of the
provisions of Article V, only the Pro Rata Administrative Agent may take the actions set forth in this Section 9.2. 

Section 9.3 Actions in Respect of Letters of Credit. At any time (i) upon the Revolving Credit Termination Date,
(ii) after the Revolving Credit Termination Date when the aggregate funds on deposit in L/C Cash Collateral Accounts shall be less than 105% of the L/C Obligations for all Letters of Credit at such time and (iii) as required by
Section 2.12, the Borrower shall pay to the Applicable Administrative Agent in immediately available funds at the Applicable Administrative Agent’s office referred to in Section 11.11, for deposit in a L/C Cash
Collateral Account, the amount required so that, after such payment, the aggregate funds on deposit in the L/C Cash Collateral Accounts equal or exceed 105% of the L/C Obligations for all Letters of Credit at such time (not to exceed, in the case of
clause (iii) above, the payment to be applied pursuant to Section 2.12 to provide cash collateral for Letters of Credit). 

ARTICLE X 
 THE ADMINISTRATIVE
AGENTS 
 Section 10.1 Appointment and Duties. 

(a) Appointment of Agents. Each Lender and each L/C Issuer hereby irrevocably designates and appoints (x) GE Capital (together with
any successor Pro Rata 

  
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Administrative Agent and Collateral Agent pursuant to Section 10.9) as the Pro Rata Administrative Agent and Collateral Agent hereunder and under the other Loan Documents and
(y) Goldman (together with any successor B Term Loan Administrative Agent pursuant to Section 10.9) as the B Term Loan Administrative Agent hereunder and under the other Loan Documents, and authorizes each Agent to (i) execute
and deliver the Loan Documents to which it is to be a party and accept delivery thereof on its behalf from any Group Member, (ii) take such action on its behalf and exercise all rights, powers and remedies and perform the duties as are
expressly delegated to each such Agent under the Loan Documents and (iii) exercise such powers as are reasonably incidental thereto. 

(b) Duties as Collateral and Disbursing Agent. Without limiting the generality of clause (a) above, the Agents shall have
the sole and exclusive right and authority (to the exclusion of the Lenders and L/C Issuers), and are hereby authorized, to (i) act as the disbursing and collecting agent for the Lenders and the L/C Issuers with respect to all payments and
collections arising in connection with the Loan Documents (including in any proceeding described in Section 9.1(e)(ii) or any other bankruptcy, insolvency or similar proceeding), and each Person making any payment in connection with any
Loan Document to any Secured Party is hereby authorized to make such payment to the applicable Agent, (ii) file and prove claims and file other documents necessary or desirable to allow the claims of the Secured Parties with respect to any
Obligation in any proceeding described in Section 9.1(e)(ii) or any other bankruptcy, insolvency or similar proceeding (but not to vote, consent or otherwise act on behalf of such Secured Party), (iii) in the case of the Collateral
Agent, (x) act as collateral agent for each Secured Party for purposes of the perfection of all Liens created by such agreements and all other purposes stated therein, (y) manage, supervise and otherwise deal with the Collateral and
(z) take such other action as is necessary or desirable to maintain the perfection and priority of the Liens created or purported to be created by the Loan Documents, (iv) except as may be otherwise specified in any Loan Document, exercise
all remedies given to the Agents and the other Secured Parties with respect to the Collateral, whether under the Loan Documents, applicable Requirements of Law or otherwise and (v) execute any amendment, consent or waiver under the Loan
Documents on behalf of any Lender that has consented in writing to such amendment, consent or waiver; provided, however, that the Collateral Agent hereby appoints, authorizes and directs each other Agent, Lender and L/C Issuer to act
as collateral sub-agent for the Agents, the Lenders and the L/C Issuers for purposes of the perfection of all Liens with respect to the Collateral, including any deposit account maintained by a Loan Party with, and cash and Cash Equivalents held by,
such other Agent, Lender or L/C Issuer, and may further authorize and direct the other Agents, the Lenders and the L/C Issuers to take further actions as collateral sub-agents for purposes of enforcing such Liens or otherwise to transfer the
Collateral subject thereto to the Collateral Agent or any other Agent, and each Agent, Lender and L/C Issuer hereby agrees to take such further actions to the extent, and only to the extent, so authorized and directed. 

(c) Limited Duties. Under the Loan Documents, each Agent (i) is acting solely on behalf of the Lenders and the L/C Issuers (except
to the limited extent provided in Section 2.14(b) with respect to the Register and in Section 11.11), with duties that are entirely administrative in nature, notwithstanding the use of the defined term “Administrative
Agents”, “Pro Rata Administrative Agent”, “B Term Loan Administrative Agent”, “Collateral Agent”, “Agent”, the terms “agent”, “administrative agent” and “collateral agent”
and similar terms in any Loan Document to refer to the Applicable Administrative Agent or the Collateral Agent, which terms are used for title purposes only, (ii) is not assuming any obligation under any Loan Document other than as expressly
set forth therein or any role as agent, fiduciary or trustee of or 

  
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for any Lender, L/C Issuer or any other Secured Party and (iii) shall have no implied functions, responsibilities, duties, obligations or other liabilities under any Loan Document, and each
Lender and L/C Issuer hereby waives and agrees not to assert any claim against the Agents based on the roles, duties and legal relationships expressly disclaimed in clauses (i) through (iii) above. The provisions of this
Section 10 are solely for the benefit of the Agents, the Lenders and the L/C Issuers, and no Loan Party or Subsidiary thereof shall have any rights as a third party beneficiary of any such provisions. Notwithstanding any provision to the
contrary elsewhere in this Agreement, no Agent shall have any duties or responsibilities, except those expressly set forth herein or in any other Loan Document, or any fiduciary relationship with any Lender, other Secured Party or any other Person,
and no implied covenants, functions, responsibilities, duties, obligations or liabilities shall be read into this Agreement or any other Loan Document or otherwise exist against any Agent. In performing its functions and duties hereunder, each Agent
shall act solely as agent of the Lenders and the L/C Issuers and does not assume and shall not be deemed to have assumed any obligation towards or relationship of agency or trust with or for the Borrower or any of its Subsidiaries. 

Section 10.2 Binding Effect. Each Lender and each L/C Issuer agrees that (i) any action taken by the Agents or the
Required Lenders (or, if expressly required or permitted hereby, a greater or other proportion of the Lenders) in accordance with the provisions of the Loan Documents, (ii) any action taken by any Agent in reliance upon the instructions of
Required Lenders (or, where so required or permitted, such greater or other proportion) and (iii) the exercise by any Agent or the Required Lenders (or, where so required or permitted, such greater or other proportion) of the powers set forth
herein or therein, together with such other powers as are reasonably incidental thereto, shall be authorized and binding upon all of the Secured Parties. 

Section 10.3 Use of Discretion. 

(a) No Action without Instructions. The Agents shall not be required to exercise any discretion or take, or to omit to take, any action,
including with respect to enforcement or collection, except any action it is required to take or omit to take (i) under any Loan Document or (ii) pursuant to instructions from the Required Lenders (or, where expressly required or permitted
by the terms of this Agreement, a greater or other proportion of the Lenders). 
 (b) Right Not to Follow Certain Instructions.
Notwithstanding clause (a) above, no Agent shall be required to take, or to omit to take, any action (i) unless, upon demand, such Agent receives an indemnification satisfactory to it from the Lenders (or, to the extent applicable
and acceptable to such Administrative Agent, any other Secured Party) against all Liabilities that, by reason of such action or omission, may be imposed on, incurred by or asserted against such Agent or any Related Person thereof or (ii) that
is, in the opinion of any Agent or its counsel, contrary to any Loan Document or applicable Requirement of Law. 
 Section 10.4
Delegation of Rights and Duties. Each Agent may, upon any term or condition it specifies, delegate or exercise any of its rights, powers and remedies under, and delegate or perform any of its duties or any other action with respect to, any
Loan Document by or through any trustee, co-agent, employee, attorney-in-fact and any other Person (including any Secured Party). Any such Person shall benefit from this Article X to the extent provided by any Agent. 

  
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 Section 10.5 Reliance and Liability. (a) The Agents may, without
incurring any liability hereunder, (i) treat the payee of any Note as its holder until such Note has been assigned in accordance with Section 11.2(e), (ii) rely on the applicable Register to the extent set forth in
Section 2.14, (iii) consult with any of their respective Related Persons and, whether or not selected by it, any other advisors, accountants and other experts (including advisors to, and accountants and experts engaged by, any Loan
Party) and (iv) rely and act upon any document and information (including those transmitted by Electronic Transmission) and any telephone message or conversation, in each case believed by it to be genuine and transmitted, signed or otherwise
authenticated by the appropriate parties. Each Administrative Agent hereby agrees that it shall furnish to the other Applicable Administrative Agent, upon its request, a copy of the Register maintained by such Applicable Administrative Agent. 

(b) None of the Agents nor their respective Related Persons shall be (i) liable for any action taken or omitted to be taken by any of
them under or in connection with any Loan Document or (ii) subject to any fiduciary or other similar implied duties, regardless of whether a Default or an Event of Default has occurred and is continuing, and each Lender, each L/C Issuer and the
Borrower hereby waive and shall not assert (and the Borrower shall cause each other Loan Party to waive and agree not to assert) any right, claim or cause of action based thereon, except to the extent of liabilities resulting from the gross
negligence or willful misconduct of any Agent or, as the case may be, such Related Person (each as determined in a final, non-appealable judgment by a court of competent jurisdiction) in connection with the duties expressly set forth herein. Without
limiting the foregoing, the Agents: 
 (i) shall not be responsible or otherwise incur liability for any action or omission
taken in reliance upon the instructions of the Required Lenders (or, where expressly required or permitted by the terms of this Agreement, a greater or other proportion of the Lenders) or for the actions or omissions of any of its Related Persons
selected with reasonable care (other than employees, officers and directors of an Agent, when acting on behalf of such Agent); 

(ii) shall not be responsible to any Secured Party for the due execution, legality, validity, enforceability, effectiveness,
genuineness, sufficiency or value of, or the attachment, perfection or priority of any Lien created or purported to be created under or in connection with, any Loan Document; 

(iii) make no warranty or representation, and shall not be responsible, to any Secured Party for any statement, document,
information, representation or warranty made or furnished by or on behalf of any Related Person or any Loan Party in connection with any Loan Document or any transaction contemplated therein or any other document or information with respect to any
Loan Party, whether or not transmitted or (except for documents expressly required under any Loan Document to be transmitted to the Lenders) omitted to be transmitted by any Agent, including as to completeness, accuracy, scope or adequacy thereof,
or for the scope, nature or results of any due diligence performed by any Agent in connection with the Loan Documents; 

(iv) shall not have any duty to ascertain or to inquire as to the performance or observance of any provision of any Loan
Document, whether any condition set forth in any Loan Document is satisfied or waived, as to the financial condition of any Loan Party or any Subsidiary thereof or as to the existence or continuation or possible occurrence or continuation of any
Default or Event of Default 

  
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and shall not be deemed to have notice or knowledge of such occurrence or continuation unless it has received a notice from the Borrower, any Lender or L/C Issuer describing such Default or Event
of Default clearly labeled “notice of default” (in which case the applicable Agent shall promptly give notice of such receipt to all Lenders); and 

(v) anything contained herein to the contrary notwithstanding, shall not have any liability arising from confirmations of the
amount of outstanding Loans or the L/C Exposure or the component amounts thereof; 
 and, for each of the items set forth in clauses (i) through
(iv) above, each Lender, L/C Issuer and the Borrower hereby waives and agrees not to assert (and the Borrower shall cause each other Loan Party to waive and agree not to assert) any right, claim or cause of action it might have against
the Agents based thereon. 
 Section 10.6 Agents Individually. The Agents and their respective Affiliates may make loans
and other extensions of credit to, acquire Stock and Stock Equivalents of, engage in any kind of business with, any Loan Party or Affiliate thereof as though it were not acting as an Agent and may receive separate fees and other payments therefor.
To the extent any Agent or any of its Affiliates makes any Loan or otherwise becomes a Lender hereunder, it shall have and may exercise the same rights and powers hereunder and shall be subject to the same obligations and liabilities as any other
Lender and the terms “Lender”, “Revolving Credit Lender”, “Term Loan Lender”, “Majority Lenders”, “Required Lenders”, “Required Revolving Credit Lenders”, “Required Pro Rata
Lenders”, “Required B Term Loan Lenders” and “Required Term Loan Lenders” and any similar terms shall, except where otherwise expressly provided in any Loan Document, include, without limitation, any Agent or such Affiliate,
as the case may be, in its individual capacity as Lender, Revolving Credit Lender, Term Loan Lender or as one of the Majority Lenders, Required Lenders, Required Revolving Credit Lenders, Required Pro Rata Lenders or Required Term Loan Lenders,
respectively. 
 Section 10.7 Lender Credit Decision. Each Lender and each L/C Issuer acknowledges that it shall,
independently and without reliance upon any Agent, any Lender or any L/C Issuer or any of their Related Persons or upon any document (including the Disclosure Documents) solely or in part because such document was transmitted by any Agent or any of
its Related Persons, conduct its own independent investigation of the financial condition and affairs of each Loan Party and its Subsidiaries and make and continue to make its own credit decisions in connection with entering into, and taking or not
taking any action under, any Loan Document or with respect to any transaction contemplated in any Loan Document, in each case based on such documents and information as it shall deem appropriate. Except for documents expressly required by any Loan
Document to be transmitted by any Agent to the Lenders or L/C Issuers, no Agent shall have any duty or responsibility to provide any Lender or L/C Issuer with any credit or other information concerning the business, prospects, operations, property,
financial and other condition or creditworthiness of any Loan Party or any Affiliate of any Loan Party that may come into the possession of any Agent or any of its Related Persons. Each Lender, by delivering its signature page to this Agreement or
an Assignment and funding its Loan, shall be deemed to have acknowledged receipt of, and consented to and approved, each Loan Document and each other document required to be approved by any Agent, the Required Lenders or the Lenders, as applicable,
on the Closing Date. 
 Section 10.8 Expenses; Indemnities. (a) Each Lender agrees to reimburse each Agent and each
of its Related Persons (to the extent not reimbursed by any Loan Party) promptly upon 

  
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demand for such Lender’s Pro Rata Share with respect to the Facilities of any costs and expenses (including fees, charges and disbursements of financial, legal and other advisors and Other
Taxes paid in the name of, or on behalf of, any Loan Party) that may be incurred by any Agent or any of its Related Persons in connection with the preparation, syndication, execution, delivery, administration, modification, consent, waiver or
enforcement (whether through negotiations, through any work-out, bankruptcy, restructuring or other legal or other proceeding or otherwise) of, or legal advice in respect of its rights or responsibilities under, any Loan Document. 

(b) Each Lender further severally agrees to indemnify the Agents and each of their respective Related Persons (to the extent not reimbursed by
any Loan Party) from and against such Lender’s aggregate Pro Rata Share with respect to the Facilities of the Liabilities (including taxes, interests and penalties imposed for not properly withholding or backup withholding on payments made to
on or for the account of any Lender) that may be at any time (whether before or after payment of the Loans) imposed on, incurred by or asserted against any Agent or any of its Related Persons in any matter relating to or arising out of, in
connection with or as a result of any Loan Document, the Transactions or any other act, event or transaction related, contemplated in or attendant to any such document, or, in each case, any action taken or omitted to be taken by any Agent or any of
its Related Persons under or with respect to any of the foregoing (IN ALL CASES, WHETHER OR NOT CAUSED OR ARISING, IN WHOLE OR IN PART, OUT OF THE COMPARATIVE, CONTRIBUTORY OR SOLE NEGLIGENCE OF ANY AGENT OR ANY OF THEIR RESPECTIVE RELATED
PARTIES); provided, however, that no Lender shall be liable to any Agent or any of its Related Persons to the extent such liability has resulted primarily from the gross negligence or willful misconduct of such Agent or, as the
case may be, such Related Person, as determined by a court of competent jurisdiction in a final and non-appealable judgment or order. 

Section 10.9 Resignation of Agent or L/C Issuer. (a) Either Administrative Agent may resign as Pro Rata Administrative
Agent or B Term Loan Administrative Agent, as applicable, at any time by delivering notice of such resignation to the Lenders, such other Applicable Administrative Agent and the Borrower, effective on the date set forth in such notice or, if no such
date is set forth therein, upon the date such notice shall be effective; provided that any resignation by the Pro Rata Administrative Agent as such shall also constitute a resignation by the Pro Rata Administrative Agent as Collateral Agent.
If the Pro Rata Administrative Agent or B Term Loan Administrative Agent delivers any such notice, (x) in the case of the Pro Rata Administrative Agent, the Required Pro Rata Lenders shall have the right to appoint a successor Pro Rata
Administrative Agent (and Collateral Agent) and (y) in the case of the B Term Loan Administrative Agent, the Required B Term Loan Lenders shall have the right to appoint a successor B Term Loan Administrative Agent. If, within 30 days after the
retiring Administrative Agent having given notice of resignation, no successor Pro Rata Administrative Agent (or Collateral Agent) or B Term Loan Administrative Agent, as applicable, has been appointed by the Required Pro Rata Lenders or B Term Loan
Lenders, as applicable, and has accepted such appointment, then the retiring Administrative Agent may, on behalf of the Lenders, appoint a B Term Loan Administrative Agent or Pro Rata Applicable Administrative Agent (and, if applicable, Collateral
Agent), as applicable, from among the Lenders. If neither the Required Pro Rata Lenders nor the Required B Term Loan Lenders, as applicable, nor the B Term Loan Administrative Agent or Pro Rata Applicable Administrative Agent, as applicable, have
appointed a successor B Term Loan Administrative Agent or Pro Rata Applicable Administrative Agent (and it applicable, Collateral Agent), as applicable, (x) in the case of the resignation of the Pro Rata Administrative Agent, the Required Pro
Rata Lenders shall be deemed to have 

  
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succeeded to and become vested with all the rights, powers, privileges and duties of the resigning Pro Rata Administrative Agent (and if applicable, Collateral Agent) and (y) in the case of
the resignation of the B Term Loan Administrative Agent, the Required B Term Loan Lenders shall be deemed to have succeeded to and become vested with all the rights, powers, privileges and duties of the resigning B Term Loan Administrative Agent ;
provided that, in the case of a resignation of the Pro Rata Administrative Agent, until a successor Pro Rata Administrative Agent is so appointed by the Required Pro Rata Lenders or the Pro Rata Administrative Agent, any Collateral held by
the Pro Rata Administrative Agent in its role as Collateral Agent on behalf of the Lenders or any other Secured Party under any of the Loan Documents shall continue to be held by the resigning Pro Rata Administrative Agent as Collateral Agent as
nominee until such time as a successor Pro Rata Administrative Agent is appointed. After any resigning Administrative Agent’s resignation as an Administrative Agent, the provisions of this Section 10 shall inure to its benefit as to
any actions taken or omitted to be taken by it while it was an Agent hereunder. Any successor Pro Rata Administrative Agent appointed pursuant to this Section 10.9 shall, upon its acceptance of such appointment, become the successor
Collateral Agent for all purposes hereunder. Each appointment under this clause (a) shall be subject to the prior consent of the Borrower, which may not be unreasonably withheld but shall not be required during the continuance of an Event of
Default. 
 (b) Effective immediately upon its resignation, (i) the retiring Agent shall be discharged from its duties and obligations
under the Loan Documents, (ii) the Lenders shall assume and perform all of the duties of such retiring Agent until a successor Agent shall have accepted a valid appointment hereunder, (iii) the retiring Agent and its Related Persons shall
no longer have the benefit of any provision of any Loan Document other than with respect to any actions taken or omitted to be taken while such retiring Agent was, or because such Agent had been, validly acting as an Agent under the Loan Documents
and (iv) subject to its rights under Section 10.3, the retiring Agent shall take such action as may be reasonably necessary to assign to the successor Agent its rights as Agent under the Loan Documents. Effective immediately upon
its acceptance of a valid appointment as Agent a successor Administrative Agent shall succeed to, and become vested with, all the rights, powers, privileges and duties of the retiring Agent under the Loan Documents. 

(c) Notwithstanding anything to the contrary contained herein, any L/C Issuer may, upon 30 days’ notice to the Borrower and the Lenders,
resign as an L/C Issuer; provided that, on or prior to the expiration of such 30-day period with respect to such resignation, the L/C Issuer shall have identified, in consultation with the Borrower, a successor L/C Issuer willing to accept
its appointment as successor L/C Issuer. In the event of any such resignation of an L/C Issuer, the Borrower shall be entitled to appoint from among the Lenders willing to accept such appointment a successor L/C Issuer hereunder; provided
that, no failure by the Borrower to appoint any such successor shall affect the resignation of the L/C Issuer. Upon such resignation, the L/C Issuer shall remain an L/C Issuer and shall retain its rights and obligations in its capacity as such
(other than any obligation to Issue Letters of Credit but including the right to receive fees or to have Lenders participate in any L/C Reimbursement Obligation thereof) with respect to Letters of Credit issued by such L/C Issuer prior to the date
of such resignation and shall otherwise be discharged from all other duties and obligations under the Loan Documents. 

  
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 Section 10.10 Release of Collateral or Guarantors. Each Lender and L/C Issuer
hereby consents to the release and hereby directs the Agents to release (or, in the case of clause (b)(ii) below, release or subordinate) the following: 

(a) any Subsidiary of the Borrower from its guaranty of any Obligation of any Loan Party if either (x) all of the Securities of such
Subsidiary owned by any Group Member are Sold in a Sale permitted under the Loan Documents (including pursuant to a waiver or consent), to the extent that, after giving effect to such Sale, such Subsidiary would not be required to guaranty any
Obligations pursuant to Section 7.10 or (y) such Subsidiary is designated as an Unrestricted Subsidiary in accordance with the terms of this Agreement; and 

(b) any Lien held by the Collateral Agent or any other Agent for the benefit of any of the Secured Parties against (i) any Collateral
that is Sold by a Loan Party in a Sale permitted by the Loan Documents (including pursuant to a valid waiver or consent), to the extent all Liens required to be granted in such Collateral pursuant to Section 7.10 after giving effect to
such Sale have been granted, (ii) any property subject to a Lien permitted hereunder in reliance upon Section 8.2(d) or (e), (iii) any Collateral owned by a Guarantor that is released from its guaranty as provided in
Section 10.10(a) and (iv) all of the Collateral and all Loan Parties, upon (A) termination of the Commitments, (B) payment and satisfaction in full of all Loans, all L/C Reimbursement Obligations and all other Obligations
that the either Administrative Agent has been notified in writing are then due and payable by the holder of such Obligation, (C) deposit of cash collateral with respect to all contingent Obligations (other than contingent indemnification
obligations as to which no claim has been asserted) (or, in the case of any L/C Obligation, a back-up letter of credit has been issued), in amounts and on terms and conditions and with parties satisfactory to the Administrative Agents and each
Indemnitee that is owed such Obligations and (D) to the extent requested by any Agent, receipt by the Secured Parties of liability releases from the Loan Parties, each in form and substance reasonably acceptable to the Agents. 

Each Lender and L/C Issuer hereby directs the Agents, and the Agents hereby agree, upon receipt of reasonable advance notice from the Borrower, to execute and
deliver or file such documents and to perform other actions reasonably necessary to release the guaranties and Liens when and as directed in this Section 10.10. 

Section 10.11 Additional Secured Parties. The benefit of the provisions of the Loan Documents directly relating to the
Collateral or any Lien granted thereunder shall extend to and be available to any Secured Party that is not a Lender or L/C Issuer as long as, by accepting such benefits, such Secured Party agrees, as among the Agents and all other Secured Parties,
that such Secured Party is bound by (and, if requested by any Agent, shall confirm such agreement in a writing in form and substance acceptable to the Agents) this Article X, Section 11.8 , Section 11.9 and
Section 11.20 and the decisions and actions of the Agents and the Required Lenders (or, where expressly required or permitted by the terms of this Agreement, a greater or other proportion of the Lenders) to the same extent a Lender is
bound; provided, however, that, notwithstanding the foregoing, (a) such Secured Party shall be bound by Section 10.8 only to the extent of Liabilities, costs and expenses with respect to or otherwise relating to the
Collateral held for the benefit of such Secured Party, in which case the obligations of such Secured Party thereunder shall not be limited by any concept of Pro Rata Share or similar concept, (b) except as set forth specifically herein, each of
the Agents, the Lenders and the L/C Issuers shall be entitled to act at its sole discretion, without regard to the interest of such Secured Party, regardless of whether any Obligation to such Secured Party thereafter remains outstanding, is deprived
of the benefit of the Collateral, becomes unsecured or is otherwise affected or put in jeopardy thereby, and without any duty or liability to such Secured Party or any such Obligation and (c) except as set forth specifically herein, such
Secured Party shall not have any right to be notified of, consent to, direct, require or be heard with respect to, any action taken or omitted in respect of the Collateral or under any Loan Document. 

  
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 Section 10.12 Titles. Notwithstanding anything else to the contrary in this
Agreement or any other Loan Document, no party hereto designated as a documentation agent, a syndication agent, an arranger or a bookrunner shall have any duties or responsibilities under this Agreement or any other Loan Document nor any fiduciary
duty to any Lender, L/C Issuer or any other Secured Party, and no implied covenants, functions, responsibilities, duties obligations or liabilities shall be read into this Agreement or otherwise exist against any such documentation agent,
syndication agent, arranger or bookrunner, in such capacity. 
 Section 10.13 Withholding Taxes. To the extent required
by any applicable law, either Administrative Agent may withhold from any payment to any Lender an amount equivalent to any applicable withholding Tax. Without duplication of the provisions of Section 2.17(e), if the Internal Revenue
Service or any other Governmental Authority asserts a claim that such Administrative Agent did not properly withhold Taxes from amounts paid to or for the account of any Lender because the appropriate form was not delivered or was not properly
executed or because such Lender failed to notify such Administrative Agent of a change in circumstance which rendered the exemption from, or reduction of, withholding Taxes ineffective or for any other reason, or if such Administrative Agent
reasonably determines that a payment was made to a Lender pursuant to this Agreement without deduction of applicable withholding Taxes from such payment, such Lender shall severally indemnify such Administrative Agent fully for all amounts paid,
directly or indirectly, by such Administrative Agent as Taxes or otherwise, including any penalties or interest and together with all expenses (including legal expenses, allocated internal costs and out-of-pocket expenses) incurred. 

ARTICLE XI 
 MISCELLANEOUS 

Section 11.1 Amendments, Waivers, Etc. (a) Except as otherwise expressly set forth in this Agreement or in any other Loan
Document, no amendment or waiver of any provision of any Loan Document (other than the Fee Letters, the Control Agreements, the L/C Reimbursement Agreements, the Secured Hedging Agreements and the Secured Treasury Services Agreements and any other
Loan Document executed pursuant to any of the foregoing) and no consent to any departure by any Loan Party therefrom shall be effective unless the same shall be in writing and signed by the Required Lenders (or by the Administrative Agents with the
consent of the Required Lenders) and the applicable Loan Party, as the case may be; provided that, no such amendment, waiver or consent shall: 

(i) extend or increase the Commitment of any Lender without the written consent of such Lender (it being understood that a
waiver of any condition precedent set forth in Section 3.2 or of any Default, Event of Default, mandatory prepayment or mandatory reduction of any Commitments shall not constitute an extension or increase of any Commitment of any
Lender); 
 (ii) postpone any date scheduled for, or reduce the amount of, any payment of principal or interest, without the
written consent of each Lender directly and adversely affected thereby, it being understood that this clause (ii) shall not apply to (x) any waiver of (or amendment to the terms of) any mandatory prepayment of the Loans (other than
pursuant to Section 2.6), (y) any change to the definition of “Consolidated 

  
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Secured Leverage Ratio” or in the component definitions thereof and (z) any waiver or amendment of Section 2.9(c) or any other provision increasing any interest rate or fee
during the continuance of an Event of Default or to any payment of any such increase; 
 (iii) reduce or forgive the
principal of, or the rate of interest specified herein on, any Loan or L/C Obligation, or any fees or other amounts payable hereunder or under any other Loan Document (or extend the timing of payments of such fees or other amounts) without the
written consent of each Lender directly and adversely affected thereby, it being understood that this clause (iii) shall not apply to (x) any waiver of (or amendment to the terms of) any mandatory prepayment of the Loans (other than
pursuant to Section 2.6), (y) any change to the definition of “Consolidated Secured Leverage Ratio” or in the component definitions thereof, or (z) any waiver or amendment of Section 2.9(c); 

(iv) except as provided in Section 10.10 (as originally in effect), release all or substantially all of the
Collateral, or release all or substantially all of the value of the Guaranties , in each case, without the consent of each Lender; 

(v) change any provision of this Section 11.1 or the definition of “Required Revolving Credit Lenders”,
“Required Tem Loan Lenders”, “Required Lenders”, “Majority Lenders” or “Required Pro Rata Lenders”, “Required B Term Loan Lenders” or any other provision specifying the number of Lenders or portion
of the Loans or Commitments required to take any action under the Loan Documents, without the written consent of each Lender directly and adversely affected thereby (it being understood that each Lender shall be directly and adversely affected by a
change to the “Required Lenders” or “Pro Rata Share” definitions); 
 (vi) amend, modify or waive
(A) any provision of any Loan Document so as to alter the ratable sharing of payments required thereby (including Sections 2.12 and 11.9) without the written consent of each Lender directly and adversely affected thereby or
(B) the definition of “Term Loan Percentage” or “Revolving Credit Percentage” without the written consent of each Lender; 

(vii) subordinate the Obligations under the Loan Documents to any other Indebtedness without the written consent of each Lender
directly or adversely affected thereby; 
 (viii) permit assignment of rights and obligations of the Borrower hereunder
without the written consent of each Lender; 
 (ix) amend Section 2.12(b) or Section 2.12(c) without
the consent of each Lender directly and adversely affected thereby; or 
 (x) (1) waive any condition set forth in
Section 3.2 or (2) amend, waive or otherwise modify any term or provision which directly affects Revolving Credit Lenders under one or more Tranches of Revolving Credit Commitments and does not directly affect Lenders under any
other Tranche, in each case, without the written consent of the Majority Lenders under such applicable Tranche or Tranches of Revolving Credit Commitments (and in the case of multiple Tranches which are affected, such Revolving Lenders shall consent
together as one Tranche) (it being understood that the written consent of the Required Lenders shall not be required for any waiver, amendment or other modification pursuant to this clause (x)); 

  
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 and provided, further, that (v) in the case of any amendment necessary to implement an
Incremental Term Loan Facility in accordance with Section 2.19 (including any increase in the Applicable Margin applicable to existing Term Loans that becomes effective on the date on which any Incremental Amendment becomes effective) or
any Incremental Revolving Credit Commitments in accordance with Section 2.19, only the consent of the Borrower, each Increasing Lender, each New Lender and the Applicable Administrative Agent as set forth in Section 2.19
shall be required to effect such amendment, (w) in the case of any Refinancing Amendment in accordance with Section 2.22, only the consent of the Borrower, each Lender providing such Specified Refinancing Term Loans or Specified
Refinancing Revolving Credit Commitments and the Administrative Agents as set forth in Section 2.22 shall be required to effect such Refinancing Amendment, (x) in the case of any Extension Amendment in accordance with
Section 2.23, only the consent of the Borrower, each Extending Lender and the Applicable Administrative Agent as set forth in Section 2.23 shall be required to effect such Extension Amendment, (y) no amendment, consent
or waiver shall amend or otherwise modify any term or provision of (i) Article V, (ii) Section 9.1(c) (solely as it relates to Article V) or (iii) the definition of “Consolidated Secured Leverage
Ratio” (or any of its component definitions (as used in Article V but not as used in other Sections of this Agreement)) without the written consent of the Required Pro Rata Lenders (and the consent of the Required Lenders shall not be
required in connection therewith), and (z) no amendment, waiver or consent shall affect the rights or duties under any Loan Document of, or any payment to, any Agent (or otherwise modify any provision of Article X or the application
thereof), the Swingline Lender, any L/C Issuer or any SPV that has been granted an option pursuant to Section 11.2(f) unless in writing and signed by, as the case may be, such Agent, the Swingline Lender, such L/C Issuer or such SPV in
addition to any signature otherwise required. No amendment, modification or waiver of this Agreement or any Loan Document altering the ratable treatment of Obligations arising under Secured Hedging Agreements or Secured Treasury Services Agreements
resulting in such Obligations being junior in right of payment to principal of the Loans or resulting in Obligations owing to any Secured Hedging Counterparty or any Secured Treasury Services Creditor being unsecured (other than releases of Liens in
accordance with the terms hereof), in each case in a manner adverse to any Secured Hedging Counterparty or any Secured Treasury Services Creditor, as the case may be, shall be effective without the written consent of such Secured Hedging
Counterparty or such Secured Treasury Services Creditor, as the case may be, or, in the case of a Secured Hedging Agreement provided or arranged by any Administrative Agent or an Affiliate thereof, such Administrative Agent. It is understood and
agreed that the rights and benefits of any Secured Hedging Counterparty or any Secured Treasury Services Creditor under the Loan Documents consist exclusively of such Secured Hedging Counterparty’s or such Secured Treasury Service
Creditor’s rights under this Section 11.1 and the right to share in payments and collections out of the Collateral as more fully set forth (and subject to the limitations set forth) herein and therein and to receive payments,
if any, in accordance with Section 2.12(c). 
 (b) Each waiver or consent under any Loan Document shall be effective only in the
specific instance and for the specific purpose for which it was given. No notice to or demand on any Loan Party shall entitle any Loan Party to any notice or demand in the same, similar or other circumstances. No failure on the part of any Secured
Party to exercise, and no delay in exercising, any right hereunder shall operate as a waiver thereof, nor shall any single or partial exercise of any such right preclude any other or further exercise thereof or the exercise of any other right. 

  
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 (c) In addition, this Agreement may be amended (or amended and restated) with the written consent
of the Required Lenders, the Administrative Agents and the Borrower (a) to add one or more additional credit facilities to this Agreement and to permit the extensions of credit from time to time outstanding thereunder and the accrued interest
and fees in respect thereof to share ratably in the benefits of this Agreement and the other Loan Documents with the Term Loans, Revolving Loans, Incremental Term Loans, Incremental Revolving Credit Commitments, Extended Term Loans, Extended
Revolving Loans or Swing Loans and L/C Obligations and the accrued interest and fees in respect thereof and (b) to include appropriately the Lenders holding such credit facilities in any determination of the Required Lenders. 

(d) Notwithstanding the foregoing, only the consent of the Borrower, the Required Lenders and the Majority Lenders under any Tranche directly
and adversely affected thereby shall be required to waive the implementation of, or amend the definition of, the Scheduled A Term Loan Springing Maturity Date, the Scheduled B Term Loan Springing Maturity Date and/or the Scheduled Revolving Credit
Springing Termination Date, as the case may be. 
 (e) Notwithstanding the foregoing, only the consent of the Borrower and the Collateral
Agent shall be required to grant a new Lien for the benefit of the Secured Parties or to extend an existing Lien over additional property. 

(f) Notwithstanding the foregoing, if, following the Closing Date, the Administrative Agents and the Borrower shall have agreed in their sole
and absolute discretion that there is an ambiguity, inconsistency, defect or manifest error or any error or omission of a technical or immaterial nature, in each case, in any provision of the Loan Documents, then the Administrative Agents and the
Borrower shall be permitted to amend such provision and such amendment shall become effective without any further action or consent of any other party to any Loan Documents if the same is not objected to in writing by the Required Lenders within 5
Business Days following receipt of notice thereof (it being understood that the Administrative Agents have no obligation to agree to any such amendment). 

Section 11.2 Assignments and Participations; Binding Effect. 

(a) Binding Effect. This Agreement shall become effective when it shall have been executed by the Borrower, the Collateral Agent, the
Administrative Agents, each Lender and each L/C Issuer that such Lender or L/C Issuer has executed it. Thereafter, it shall be binding upon and inure to the benefit of, but only to the benefit of, the Borrower (except for Article X), the
Collateral Agent, the Administrative Agents, each Lender and L/C Issuer and, to the extent provided in Section 10.11, each other Indemnitee and Secured Party and, in each case, their respective successors and permitted assigns. Except as
expressly provided in any Loan Document (including in Section 10.9), none of the Borrower, any L/C Issuer, the Collateral Agent or any Administrative Agent shall have the right to assign any rights or obligations hereunder or any
interest herein. 
 (b) Right to Assign. Each Lender may sell, transfer, negotiate or assign all or a portion of its rights and
obligations under this Agreement (including all or a portion of its Commitments and the Loans (including for purposes of this Section 11.2(b), participations in L/C 

  
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Obligations and in Swing Loans) at the time owing to it) to (each an “Eligible Assignee”): (i) any existing Lender; provided that no such sale, transfer, negotiation
or assignment may be made to any such Person that is, to the knowledge of such assigning Lender, a Defaulting Lender, (ii) any Affiliate or Approved Fund of any existing Lender; provided that no such sale, transfer, negotiation or
assignment may be made to any such Person that is a natural person or, to the knowledge of such assigning Lender, a Defaulting Lender, or (iii) any other Person (other than a natural person, the Borrower or any of its Subsidiaries except as
provided in Section 2.21) with the consent (which consent shall not be unreasonably withheld, conditioned or delayed) of (x) the Applicable Administrative Agent, and (y) in the case of any sale, transfer, negotiation or
assignment of Revolving Credit Commitments (and related Obligations) only, (I) the Swingline Lender, (II) each L/C Issuer, and (III) as long as no Event of Default is continuing, the Borrower; provided, however, that (A) the
Borrower shall be deemed to have consented to any such sale, transfer, negotiation or assignment unless it shall object thereto by written notice to the Applicable Administrative Agent within 5 Business Days after having received notice thereof,
(B) such sales, transfers, negotiations or assignments do not have to be ratable between the Facilities but must be ratable among the Obligations owing to and the obligations owed by such Lender with respect to a Facility and (C) for each
Facility, the aggregate outstanding principal amount (determined as of the effective date of the applicable Assignment or other sale, transfer, negotiation or assignment) of the Loans, Commitments and L/C Obligations subject to any such sale,
transfer, negotiation or assignment shall be in a minimum amount of $1,000,000 in the case of a sale, transfer, negotiation or assignment of Term Loans and $5,000,000 in the case of a sale, transfer, negotiation or assignment of Revolving Loans and
Revolving Credit Commitments, unless such sale, transfer, negotiation or assignment is made to an existing Lender or an Affiliate or Approved Fund of any existing Lender, is of the assignor’s (together with its Affiliates and Approved Funds)
entire interest in such Facility or is made with the prior consent of the Borrower and the Applicable Administrative Agent. Assignments shall not be required to be pro rata among the Facilities. Notwithstanding the foregoing or anything to the
contrary set forth herein, to the extent any Lender is required to assign any portion of its Commitments, Loans and other rights, duties and obligations hereunder in order to comply with applicable laws, such assignment may be made by such Lender
without the consent of the Borrower, any Administrative Agent, any applicable L/C Issuer, the Swingline Lender or any other party hereto so long as such Lender complies with the requirements of Sections 11.2(b) and (c). 

(c) Procedure. The parties to each sale, transfer, negotiation or assignment made in reliance on clause (b) above (other
than those described in clause (e) or (f) below) shall execute and deliver to the Applicable Administrative Agent an Assignment , which shall include, inter alia, a representation by the assignee that it is an Eligible
Assignee, evidencing such sale, transfer, negotiation or assignment, together with any existing Note subject to such sale, transfer, negotiation or assignment (or any affidavit of loss therefor acceptable to the Applicable Administrative Agent), any
tax forms required to be delivered pursuant to Section 2.17(h), an administrative questionnaire or such Applicable Administrative Agent’s customary form and payment to the Applicable Administrative Agent of an assignment fee in the
amount of $3,500 (unless waived by the Applicable Administrative Agent, but for which no Group Member shall have any liability in any event), provided that (1) if a sale, transfer, negotiation or assignment by a Lender is made to
an Affiliate or an Approved Fund of such assigning Lender, then no assignment fee shall be due in connection with such sale, transfer, negotiation or assignment, (2) if a sale, transfer, negotiation or assignment by a Lender is made to an
assignee that is not an Affiliate or Approved Fund of such assignor Lender, and concurrently to one or more Affiliates or Approved Funds of such assignee, then only one assignment fee of $3,500 shall be due in

  
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connection with such sale, transfer, negotiation or assignment and (3) no assignment fee shall be payable for assignments to and from any of the Arrangers or any of their respective
Affiliates. Upon receipt of all the foregoing, and conditioned upon such receipt and, if such assignment is made in accordance with Section 11.2(b)(iii), upon the Applicable Administrative Agent (and the Borrower, if applicable)
consenting to such Assignment, from and after the effective date specified in such Assignment, the Applicable Administrative Agent shall record or cause to be recorded in the applicable Register the information contained in such Assignment. The
entries in the applicable Register shall be conclusive, absent manifest error, and the Borrower, the Agents and the Lenders shall treat each Person whose name is recorded in the applicable Register pursuant to the terms hereof as a Lender hereunder
for all purposes of this Agreement, notwithstanding notice to the contrary. Each Register shall be available for inspection by the Borrower, any Agent and any Lender (solely with respect to itself), at any reasonable time and from time to time upon
reasonable prior notice. 
 (d) Effectiveness. Subject to the recording of an Assignment by the applicable Administrative Agent in
the applicable Register pursuant to Section 2.14(b), (i) the assignee thereunder shall become a party hereto and, to the extent that rights and obligations under the Loan Documents have been assigned to such assignee pursuant to
such Assignment, shall have the rights and obligations of a Lender, (ii) any applicable Note shall be transferred to such assignee through such entry and (iii) the assignor thereunder shall, to the extent that rights and obligations under
this Agreement have been assigned by it pursuant to such Assignment, relinquish its rights (except for those surviving the termination of the Commitments and the payment in full of the Obligations) and be released from its obligations under the Loan
Documents, other than those relating to events or circumstances occurring prior to such assignment (and, in the case of an Assignment covering all or the remaining portion of an assigning Lender’s rights and obligations under the Loan
Documents, such Lender shall cease to be a party hereto except that each Lender agrees to remain bound by Article X, Section 11.8 and Section 11.9 to the extent provided in Section 10.11). 

(e) Grant of Security Interests. In addition to the other rights provided in this Section 11.2, each Lender may grant a
security interest in, or otherwise assign as collateral, any of its rights under this Agreement, whether now owned or hereafter acquired (including rights to payments of principal or interest on the Loans), to (A) any federal reserve bank
(pursuant to Regulation A of the Federal Reserve Board), without notice to the Administrative Agents or (B) any holder of, or trustee for the benefit of the holders of, such Lender’s Securities by notice to the Administrative Agents;
provided, however, that no such holder or trustee, whether because of such grant or assignment or any foreclosure thereon (unless such foreclosure is made through an assignment in accordance with clause (b) above), shall be
entitled to any rights of such Lender hereunder and no such Lender shall be relieved of any of its obligations hereunder. 
 (f)
Participants and SPVs. In addition to the other rights provided in this Section 11.2, each Lender may, (x) with notice to the Administrative Agents, grant to an SPV the option to make all or any part of any Loan that such
Lender would otherwise be required to make hereunder (and the exercise of such option by such SPV and the making of Loans pursuant thereto shall satisfy the obligation of such Lender to make such Loans hereunder) and such SPV may assign to such
Lender the right to receive payment with respect to any Obligation and (y) without notice to or consent from the Administrative Agents or the Borrower, sell participations to one or more Persons (other than the Borrower or any of its
Subsidiaries) in or to all or a portion of its rights and obligations under this Agreement (including all or a portion of its 

  
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Commitments and the Loans (including for purposes of this Section 11.2(f), participations in L/C Obligations and in Swing Loans)); provided, however, that, whether as a
result of any term of any Loan Document or of such grant or participation, (i) no such SPV or participant shall have a commitment, or be deemed to have made an offer to commit, to make Loans hereunder, and, except as provided in the applicable
option agreement, none shall be liable for any obligation of such Lender hereunder, (ii) such Lender’s rights and obligations, and the rights and obligations of the Loan Parties and the Secured Parties towards such Lender, under any Loan
Document shall remain unchanged and each other party hereto shall continue to deal solely with such Lender, which shall remain the holder of the Obligations in the Register, except that (A) each such participant and SPV shall be entitled to the
benefits of such Lender under Sections 2.16 and 2.17 (subject to the requirements and limitations therein, including the requirements under Section 2.17(h) (it being understood that the documentation required under
Section 2.17(h) shall be delivered to the participating Lender)) but only to the extent of any amount to which such Lender would be entitled in the absence of any such grant or participation (without duplication of any amount paid to
such Lender pursuant to the indemnification provisions under Section 2.17) and (B) each such SPV may receive other payments that would otherwise be made to such Lender with respect to Loans funded by such SPV to the extent provided
in the applicable option agreement and set forth in a notice provided to the Administrative Agents by such SPV and such Lender, provided, however, that in no case (including pursuant to clause (A) or (B) above)
shall an SPV or participant have the right to enforce any of the terms of any Loan Document, (iii) the Borrower, the Agents and the other Lenders shall continue to deal solely and directly with such Lender in connection with such Lender’s
rights and obligations under this Agreement and (iv) the consent of such SPV or participant shall not be required (either directly, as a restraint on such Lender’s ability to consent hereunder or otherwise) for any amendments, waivers or
consents with respect to any Loan Document or to exercise or refrain from exercising any powers or rights such Lender may have under or in respect of the Loan Documents (including the right to enforce or direct enforcement of the Obligations);
provided that any agreement or instrument pursuant to which a Lender sells such a participation shall provide that such Lender shall retain the sole right to enforce this Agreement and the other Loan Documents and to approve any amendment,
modification or waiver of any provision of this Agreement or the other Loan Documents; provided, further, that such agreement or instrument may provide that such Lender will not, without the consent of the Participant, agree to any
amendment, waiver or other modification described in clauses (i) through (iv) and clause (vii) of the first proviso to Section 11.1 that requires the affirmative vote of such Lender. No party hereto
shall institute (and the Borrower shall cause each other Loan Party not to institute) against any SPV grantee of an option pursuant to this clause (f) any bankruptcy, reorganization, insolvency, liquidation or similar proceeding prior to
the date that is one year and one day after the payment in full of all outstanding commercial paper of such SPV; provided, however, that each Lender having designated an SPV as such agrees to indemnify each Indemnitee against any
Liability that may be incurred by, or asserted against, such Indemnitee as a result of failing to institute such proceeding (including a failure to be reimbursed by such SPV for any such Liability). The agreement in the preceding sentence shall
survive the termination of the Commitments and the payment in full of the Obligations. Each Lender that sells a participation shall, acting solely for this purpose as a non-fiduciary agent of the Borrower, maintain a register on which it enters the
name and address of each Participant or SPV and the principal amounts (and stated interest) of each Participant’s or SPV’s interest in the Loans or other obligations under the Loan Documents (the “Participant
Register”). The entries in the Participant Register shall be conclusive absent manifest error, and such Lender shall treat each Person whose name is recorded in the Participant Register as the owner of such participation for all purposes of
this Agreement notwithstanding any notice to the 

  
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contrary. No Lender shall have any obligation to disclose all or any portion of the Participant Register (including the identity of any Participant or any information relating to a
Participant’s interest in any commitments, loans, letters of credit or its other obligations under any Loan Document) to any Person, except that the portion of any Participant Register relating to any Participant or SPV requesting payment from
the Borrower or seeking to exercise its rights under Section 11.8 shall be available for inspection by the Borrower upon reasonable request to the extent that such disclosure is necessary to establish that such commitment, loan, letter
of credit or other obligation is in registered form under Section 5f.103-1(c) of the United States Treasury Regulations or as is otherwise required thereunder. 

Section 11.3 Costs and Expenses. Any action taken by any Loan Party under or with respect to any Loan Document, even if
required under any Loan Document or at the request of any Secured Party, shall be at the expense of such Loan Party, and no Secured Party shall be required under any Loan Document to reimburse any Loan Party or Group Member therefor except as
expressly provided therein. In addition (but without limiting the obligations of the Borrower under the Engagement Letter), the Borrower agrees to pay or reimburse upon demand (a) each of the Agents and each Arranger and any Related Person of
any of the foregoing for all reasonable out-of-pocket costs and expenses incurred by such Persons or any of their Related Persons in connection with (i) the investigation, development, preparation, negotiation, syndication, execution,
interpretation or administration of, any modification of any term of or termination of, any Loan Document, any engagement or proposal letter therefor (including the Engagement Letter), any other document prepared in connection therewith or the
consummation and administration of any transaction contemplated therein (including periodic audits in connection therewith and environmental audits and assessments), in each case limited in the case of fees, charges and disbursements of consultants
and counsel, to the reasonable fees, charges and disbursements of a single external legal counsel for all such Persons and any of their Related Persons taken as a whole and, if reasonably necessary, a single regulatory counsel and a single local
counsel in each relevant jurisdiction for all such Persons and any of their Related Persons and, solely in the case of an actual or potential conflict of interest as reasonably determined by the affected Person or Persons, one additional counsel
(including one additional regulatory and local counsel in each relevant jurisdiction) to each Person or group of affected Persons similarly situated taken as a whole (but excluding, in each case, any costs or expenses of internal legal counsel),
(ii) reasonable fees, costs and expenses incurred in connection with Intralinks®, SyndTrak Online, ClearPar® or any other E-System
and allocated to the Facilities by each Administrative Agent in its sole discretion and (iii) reasonable fees, charges and disbursements of the auditors, appraisers, printers and other of their Related Persons retained by or on behalf of any of
them or any of their Related Persons, (b) each Agent and each L/C Issuer for all reasonable costs and expenses (excluding any costs or expenses of internal counsel) incurred by it or any of its Related Persons in connection with the L/C
Back-Stop Arrangements entered into by such Persons, (c) each Agent for all reasonable costs and expenses (excluding any costs or expenses of internal counsel) incurred by it or any of its Related Persons in connection with internal audit
reviews, field examinations and Collateral examinations (which shall be reimbursed, in addition to the out-of-pocket costs and expenses of such examiners, at the per diem rate per individual charged by each Agent for its examiners) and (d) each
of the Agents, their respective Related Persons, and each Lender and L/C Issuer for all costs and expenses incurred in connection with (i) any refinancing or restructuring of the credit arrangements provided hereunder in the nature of a
“work-out”, (ii) the enforcement or preservation of any right or remedy under any Loan Document, any Obligation, with respect to the Collateral or any other related right or remedy or (iii) the commencement, defense, conduct of,
intervention in, or the taking of any other action 

  
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with respect to, any proceeding (including any bankruptcy or insolvency proceeding) related to any Group Member, Loan Document, Obligation or Transaction (or the response to and preparation for
any subpoena or request for document production relating thereto), including fees and disbursements of counsel (excluding any costs or expenses of internal counsel). 

Section 11.4 Indemnities. (a) Subject to the provisions of Section 11.3 with respect to the limitations on
reimbursement of costs and expenses described therein, the Borrower agrees to indemnify, hold harmless and defend each Agent, each Arranger, each Lender, each L/C Issuer, each Secured Hedging Counterparty, each Secured Treasury Services Creditor,
each Person that each L/C Issuer causes to Issue Letters of Credit hereunder and each of their respective Related Persons (each such Person being an “Indemnitee”) from and against all Liabilities (including brokerage commissions,
fees and other compensation) that may be imposed on, incurred by or asserted against any such Indemnitee in any matter relating to or arising out of, in connection with or as a result of (i) any Loan Document, any Disclosure Document, any
Obligation (or the repayment thereof), any Letter of Credit, the use or intended use of the proceeds of any Loan or the use of any Letter of Credit, any Transaction, or any securities filing of, or with respect to, any Group Member and/or
Unrestricted Subsidiary, (ii) any engagement letter (including the Engagement Letter), proposal letter or term sheet with any Person or any Contractual Obligation, arrangement or understanding with any broker, finder or consultant, in each case
entered into by or on behalf of any Group Member or any Affiliate of any of them in connection with any of the foregoing and any Contractual Obligation entered into in connection with any E-Systems or other Electronic Transmissions, (iii) any
actual or prospective investigation, litigation or other proceeding, whether or not brought by any such Indemnitee or any of its Related Persons, any holders of Securities or creditors (and including reasonable attorneys’ fees in any case, but
excluding any costs and expenses of internal counsel), whether or not any such Indemnitee, Related Person, holder or creditor is a party thereto, and whether or not based on any securities or commercial law or regulation or any other Requirement of
Law or theory thereof, including common law, equity, contract, tort or otherwise, or (iv) any other act, event or transaction related, contemplated in or attendant to any of the foregoing (collectively, the “Indemnified
Matters”); provided, however, that the Borrower shall not have any liability under this Section 11.4 to any Indemnitee with respect to any Indemnified Matter, and no Indemnitee shall have any liability with respect
to any Indemnified Matter other than (to the extent otherwise liable), to the extent such liability has resulted from the gross negligence or willful misconduct of such Indemnitee, as determined by a court of competent jurisdiction in a final and
non-appealable judgment or order; provided, however, that in no event shall any Agent have any liability to the Loan Parties, any Lender, the Swingline Lender, any L/C Issuer or any other Person for indirect, special, incidental,
consequential or punitive damages (as opposed to direct or actual damages). Furthermore, the Borrower waives and agrees not to assert against any Indemnitee, and shall cause each other Loan Party to waive and not assert against any Indemnitee, any
right of contribution with respect to any Liabilities that may be imposed on, incurred by or asserted against any Related Person. 
 (b)
Without limiting the foregoing, “Indemnified Matters” includes all Environmental Liabilities, including those arising from, or otherwise involving, any property of any Related Person or any actual, alleged or prospective damage to
property or natural resources or harm or injury alleged to have resulted from any Release of Hazardous Materials on, upon or into such property or natural resource or any property on or contiguous to any real property of any Related Person, whether
or not, with respect to any such Environmental Liabilities, any Indemnitee is a mortgagee pursuant to any leasehold mortgage, a mortgagee in possession, the 

  
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successor-in-interest to any Related Person or the owner, lessee or operator of any property of any Related Person through any foreclosure action, in each case except to the extent such
Environmental Liabilities (i) are incurred solely following foreclosure by any Secured Party or following any Secured Party having become the successor-in-interest to any Loan Party and (ii) are attributable solely to acts of such
Indemnitee. 
 Section 11.5 Survival. Any indemnification or other protection provided to any Indemnitee pursuant
to any Loan Document (including pursuant to Section 2.16, Section 2.17, Article X , Section 11.3 and Section 11.4), this Section 11.5, Section 11.13,
Section 11.14, Section 11.15 or Section 11.20 and all representations and warranties made in any Loan Document shall (A) survive the termination of the Commitments and the payment in full of other Obligations
and (B) inure to the benefit of any Person that at any time held a right thereunder (as an Indemnitee or otherwise) and, thereafter, its successors and permitted assigns. 

Section 11.6 Limitation of Liability for Certain Damages. In no event shall the Borrower or any other Loan Party or any
Indemnitee be liable on any theory of liability for any special, indirect, consequential or punitive damages (including any loss of profits, business or anticipated savings), except, in the case of the Borrower and each other Loan Party, to the
extent that any such damages consist of or arise from claims against any Indemnitee by unaffiliated third parties. The Borrower hereby waives, releases and agrees (and shall cause each other Loan Party to waive, release and agree) not to sue upon
any such claim for any special, indirect, consequential or punitive damages, whether or not accrued and whether or not known or suspected to exist in its favor. 

Section 11.7 Lender-Creditor Relationship. The relationship between the Lenders, the L/C Issuers and the Agents, on the one
hand, and the Loan Parties, on the other hand, is solely that of lender and creditor. No Secured Party has any fiduciary relationship or duty to any Loan Party arising out of or in connection with, and there is no agency, tenancy or joint venture
relationship between the Secured Parties and the Loan Parties by virtue of, any Loan Document or any transaction contemplated therein. The Loan Parties acknowledge and agree that (i) the transactions contemplated by the Loan Documents
(including the exercise of rights and remedies hereunder and thereunder) are arm’s-length commercial transactions between the Arrangers, the Agents and the Lenders, on the one hand, and the Loan Parties, on the other, and (ii) in
connection therewith and with the process leading thereto, (x) no Arranger, Agent or Lender has assumed an advisory or fiduciary responsibility in favor of any Loan Party, its stockholders or its Affiliates with respect to the transactions
contemplated hereby (or the exercise of rights or remedies with respect thereto) or the process leading thereto (irrespective of whether any Arranger, Agent or Lender has advised, is currently advising or will advise any Loan Party, its stockholders
or its Affiliates on other matters) or any other obligation to any Loan Party except the obligations expressly set forth in the Loan Documents and (y) each Arranger, Agent and Lender is acting solely as principal and not as the agent or
fiduciary of any Loan Party, its management, stockholders, creditors or any other Person. Each Loan Party acknowledges and agrees that it has consulted its own legal and financial advisors to the extent it deemed appropriate and that it is
responsible for making its own independent judgment with respect to such transactions and the process leading thereto. Each Loan Party agrees that it will not claim that any Arrangers, Agent or Lender has rendered advisory services of any
nature or respect, or owes a fiduciary or similar duty to such Loan Party, in connection with such transaction or the process leading thereto. 

  
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 Section 11.8 Right of Setoff. Each Agent, each Lender, each L/C Issuer and
each Affiliate (including each branch office thereof) of any of them is hereby authorized, without notice or demand (each of which is hereby waived by the Borrower), at any time and from time to time during the continuance of any Event of Default
and to the fullest extent permitted by applicable Requirements of Law, to set off and apply any and all deposits (whether general or special, time or demand, provisional or final) at any time held and other Indebtedness, claims or other obligations
at any time owing by such Agent, such Lender, such L/C Issuer or any of their respective Affiliates to or for the credit or the account of the Borrower against any Obligation of any Loan Party now or hereafter existing, whether or not any demand was
made under any Loan Document with respect to such Obligation and even though such Obligation may be unmatured. Each Agent, each Lender and each L/C Issuer agrees promptly to notify the Borrower and each other Agent after any such setoff and
application made by such Agent, Lender or its Affiliates; provided, however, that the failure to give such notice shall not affect the validity of such setoff and application. The rights under this Section 11.8 are in
addition to any other rights and remedies (including other rights of setoff) that the Administrative Agents, the Lenders and the L/C Issuers and their Affiliates and other Secured Parties may have. 

Section 11.9 Sharing of Payments, Etc. (a) If any Lender, directly or through an Affiliate or branch office thereof,
obtains any payment of any Obligation of any Loan Party (whether voluntary, involuntary or through the exercise of any right of setoff or the receipt of any Collateral or “proceeds” (as defined under the applicable UCC) of
Collateral) other than pursuant to Sections 2.16, 2.17, 2.18 and 2.21 and such payment exceeds the amount such Lender would have been entitled to receive if all payments had gone to, and been distributed by, the
applicable Administrative Agent in accordance with the provisions of the Loan Documents, such Lender shall purchase for cash from other Secured Parties such participations in their Obligations as necessary for such Lender to share such excess
payment with such Secured Parties to ensure such payment is applied as though it had been received by the applicable Administrative Agent and applied in accordance with this Agreement (or, if such application would then be at the discretion of the
Borrower, applied to repay the Obligations in accordance herewith); provided, however, that (a) if such payment is rescinded or otherwise recovered from such Lender or L/C Issuer in whole or in part, such purchase shall be
rescinded and the purchase price therefor shall be returned to such Lender or L/C Issuer without interest and (b) such Lender shall, to the fullest extent permitted by applicable Requirements of Law, be able to exercise all its rights of
payment (including the right of setoff) with respect to such participation as fully as if such Lender were the direct creditor of the Borrower in the amount of such participation. 

(b) Notwithstanding anything to the contrary contained herein, the provisions of the preceding Section 11.9(a) shall be subject to
the express provisions of this Agreement which require, or permit, differing payments to be made to Non-Defaulting Lenders as opposed to Defaulting Lenders. 

Section 11.10 Marshaling; Payments Set Aside. No Secured Party shall be under any obligation to marshal any property in
favor of any Loan Party or any other party or against or in payment of any Obligation. To the extent that any Secured Party receives a payment from the Borrower, from the proceeds of the Collateral, from the exercise of its rights of setoff, any
enforcement action or otherwise, and such payment is subsequently, in whole or in part, invalidated, declared to be fraudulent or preferential, set aside or required to be repaid to a trustee, receiver or any other party, then to the extent of such
recovery, the obligation or part thereof originally intended to be satisfied, and all Liens, rights and remedies therefor, shall be revived and continued in full force and effect as if such payment had not occurred. 

  
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 Section 11.11 Notices. 

(a) Addresses. All notices, demands, requests, directions and other communications required or expressly authorized to be made by this
Agreement shall, whether or not specified to be in writing but unless otherwise expressly specified to be given by any other means, be given in writing and (i) addressed (A) if to the Borrower, to Alere Inc., 51 Sawyer Road, Suite 200,
Waltham, Massachusetts 02453, Attention: Jim Hinrichs, Chief Financial Officer, Tel: (858) 805-2426, Fax: (858) 408-9415 with copies to (1) Alere Inc., 51 Sawyer Road, Suite 200, Waltham, Massachusetts 02453, Attention: David
Teitel, Vice President, Finance, Tel: (781) 314-4174, Fax: (781) 647-3939, (2) Alere Inc., 51 Sawyer Road, Suite 200, Waltham, Massachusetts 02453, Attention: General Counsel, Tel: (781) 647-3900, Fax: (781) 647-3939,
and (3) (for informational purposes only and not constituting any required notice) Foley Hoag LLP, Seaport World Trade Center West, 155 Seaport Boulevard, Boston, Massachusetts 02210-2600, Attention: Malcolm Henderson, Esq., Tel:
(617) 832.1276, Fax: (617) 832-7000, (B) if to any other Loan Party, to such Loan Party c/o the Borrower as provided in preceding clause (A), (C) if to the B Term Loan Administrative Agent, to Goldman Sachs Bank USA, 200
West Street, New York, New York 10282, Tel: (972) 368-2323 and (972) 368-2746, Fax: (917)-977-3966, Attention: Morgan Goodwin and Ken Moua, (D) if to the Pro Rata Administrative Agent, the Collateral Agent, the L/C Issuer or the
Swingline Lender, to General Electric Capital Corporation, 2 Bethesda Metro Center, Suite 600, Bethesda, MD 20814, Attention: Alere Account Manager, Tel: (301) 634-3215, Fax: (866) 673-0624, and (E) otherwise to the party to be
notified at (i) its address specified opposite its name on Schedule II or on the signature page of any applicable Assignment, (ii) posted to Intralinks® (to the extent
such system is available and set up by or at the direction of the applicable Administrative Agent prior to posting) in an appropriate location by uploading such notice, demand, request, direction or other communication to www.intralinks.com, faxing
it to 866-545-6600 with an appropriate bar-coded fax coversheet or using such other means of posting to Intralinks® as may be available and reasonably acceptable to the applicable
Administrative Agent prior to such posting, (iii) posted to any other E-System set up by or at the direction of the Applicable Administrative Agent in an appropriate location or (iv) addressed to such other address as shall be notified in
writing (A) in the case of the Borrower, any Administrative Agent and the Swingline Lender, to the other parties hereto and (B) in the case of all other parties, to the Borrower and the Administrative Agents; provided that, each
Administrative Agent, the Collateral Agent or the Borrower, in its discretion, may agree to accept notices and other communications to it hereunder by electronic communications pursuant to procedures approved by it, it being understood that approval
of such procedures may be limited to particular notices or communications. Subject to the immediately preceding sentence and clause (b) below, transmission by electronic mail (including E-Fax, even if transmitted to the fax numbers set forth in
clause (i) above) shall not be sufficient or effective to transmit any such notice under this clause (a) unless such transmission is an available means to post to any E-System. 

(b) Effectiveness. All communications described in clause (a) above and all other notices, demands, requests and other
communications made in connection with this Agreement shall be effective and be deemed to have been received (i) if delivered by hand, upon personal delivery, (ii) if delivered by overnight courier service, one Business Day after delivery
to such courier service, (iii) if delivered by mail, when deposited in the mails, (iv) if delivered by 

  
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facsimile (other than to post to an E-System pursuant to clause (a)(ii) or (a)(iii) above), upon sender’s receipt of confirmation of proper transmission, (v) if delivered
by posting to any E-System (including any facsimile so posted), on the later of the date of such posting in an appropriate location and the date access to such posting (and notice of such access) is given to the recipient thereof in accordance with
the standard procedures applicable to such E-System and (vi) if delivered by e-mail as set forth in clause (a), upon the sender’s receipt of an acknowledgement from the intended recipient (including by the “return receipt
requested” function, as available, return e-mail or other written acknowledgement); provided, however, that no communications to the Applicable Administrative Agent pursuant to Article II or Article X shall
be effective until received by such Administrative Agent. 
 Section 11.12 Electronic Transmissions. 

(a) Authorization. Subject to the provisions of Section 11.11(a), each of the Administrative Agents, the Borrower, the
Lenders, the L/C Issuers and each of their Related Persons is authorized (but not required) to transmit, post or otherwise make or communicate, in its sole discretion, Electronic Transmissions in connection with any Loan Document and the
transactions contemplated therein. Each of the Borrower and each Secured Party hereby acknowledges and agrees, and the Borrower shall cause each other Group Member to acknowledge and agree, that the use of Electronic Transmissions is not necessarily
secure and that there are risks associated with such use, including risks of interception, disclosure and abuse and each indicates it assumes and accepts such risks by hereby authorizing the transmission of Electronic Transmissions. 

(b) Signatures. Subject to the provisions of Section 11.11(a), (i)(A) no posting to any E-System shall be denied legal
effect merely because it is made electronically, (B) each E-Signature on any such posting shall be deemed sufficient to satisfy any requirement for a “signature” and (C) each such posting
shall be deemed sufficient to satisfy any requirement for a “writing”, in each case including pursuant to any Loan Document, any applicable provision of any UCC, the federal Uniform Electronic Transactions Act, the Electronic Signatures in
Global and National Commerce Act and any substantive or procedural Requirement of Law governing such subject matter, (ii) each such posting that is not readily capable of bearing either a signature or a reproduction of a signature may be
signed, and shall be deemed signed, by attaching to, or logically associating with such posting, an E-Signature, upon which each Secured Party and Loan Party may rely and assume the authenticity thereof, (iii) each such posting containing a
signature, a reproduction of a signature or an E-Signature shall, for all intents and purposes, have the same effect and weight as a signed paper original and (iv) each party hereto or beneficiary hereto agrees not to contest the validity or
enforceability of any posting on any E-System or E-Signature on any such posting under the provisions of any applicable Requirement of Law requiring certain documents to be in writing or signed;
provided, however, that nothing herein shall limit such party’s or beneficiary’s right to contest whether any posting to any E-System or E-Signature has been altered after transmission. 

(c) Separate Agreements. All uses of an E-System shall be governed by and subject to, in addition to Section 11.11 and this
Section 11.12, separate terms and conditions posted or referenced in such E-System and related Contractual Obligations executed by Secured Parties and Group Members in connection with the use of such E-System. 

(d) Limitation of Liability. All E-Systems and Electronic Transmissions shall be provided “as is” and “as
available”. None of the Administrative Agents, any Arranger or 

  
 154 

 
any of their respective Related Persons warrants the accuracy, adequacy or completeness of any E-Systems or Electronic Transmission, and each disclaims all liability for errors or omissions
therein. No warranty of any kind is made by the Administrative Agents, any Arranger or any of their respective Related Persons in connection with any E-Systems or Electronic Transmission, including any
warranty of merchantability, fitness for a particular purpose, non-infringement of third-party rights or freedom from viruses or other code defects. Each of the Borrower and each Secured Party agrees (and the Borrower shall cause each other Loan
Party to agree) that neither the Administrative Agents nor any Arranger has any responsibility for maintaining or providing any equipment, software, services or any testing required in connection with any Electronic Transmission or otherwise
required for any E-System. 
 Section 11.13 Governing Law. THIS AGREEMENT, EACH
OTHER LOAN DOCUMENT THAT DOES NOT EXPRESSLY SET FORTH ITS APPLICABLE LAW, AND THE RIGHTS AND OBLIGATIONS OF THE PARTIES HERETO AND THERETO SHALL BE GOVERNED BY, AND CONSTRUED AND INTERPRETED IN ACCORDANCE WITH, THE LAW OF THE STATE OF NEW YORK. 

Section 11.14 Jurisdiction. 

(a) Submission to Jurisdiction. ANY LEGAL ACTION OR PROCEEDING WITH RESPECT TO ANY LOAN DOCUMENT SHALL BE BROUGHT IN THE COURTS OF THE
STATE OF NEW YORK LOCATED IN THE CITY OF NEW YORK, BOROUGH OF MANHATTAN, OR OF THE UNITED STATES OF AMERICA FOR THE SOUTHERN DISTRICT OF NEW YORK AND, BY EXECUTION AND DELIVERY OF THIS AGREEMENT, EACH PARTY HERETO HEREBY ACCEPTS FOR ITSELF AND
IN RESPECT OF ITS PROPERTY, GENERALLY AND UNCONDITIONALLY, THE EXCLUSIVE JURISDICTION OF THE AFORESAID COURTS. THE PARTIES HERETO (AND, TO THE EXTENT SET FORTH IN ANY OTHER LOAN DOCUMENT, EACH OTHER LOAN PARTY) HEREBY IRREVOCABLY WAIVE ANY
OBJECTION, INCLUDING ANY OBJECTION TO THE LAYING OF VENUE OR BASED ON THE GROUNDS OF FORUM NON CONVENIENS, THAT ANY OF THEM MAY NOW OR HEREAFTER HAVE TO THE BRINGING OF ANY SUCH ACTION OR PROCEEDING IN SUCH JURISDICTIONS;
PROVIDED THAT NOTHING IN THIS AGREEMENT OR IN ANY OTHER LOAN DOCUMENT SHALL AFFECT ANY RIGHT THAT ANY AGENT OR ANY LENDER MAY OTHERWISE HAVE TO BRING ANY ACTION OR PROCEEDING RELATING TO THIS AGREEMENT OR ANY OTHER LOAN DOCUMENT OR THE
RECOGNITION OR ENFORCEMENT OF ANY JUDGMENT AGAINST ANY LOAN PARTY OR ITS PROPERTIES IN THE COURTS OF ANY JURISDICTION. 
 (b) Service of
Process. THE BORROWER (AND, TO THE EXTENT SET FORTH IN ANY OTHER LOAN DOCUMENT, EACH OTHER LOAN PARTY) HEREBY IRREVOCABLY WAIVES PERSONAL SERVICE OF ANY AND ALL LEGAL PROCESS, SUMMONS, NOTICES AND OTHER DOCUMENTS AND OTHER SERVICE OF
PROCESS OF ANY KIND AND CONSENTS TO SUCH SERVICE IN ANY SUIT, ACTION OR PROCEEDING BROUGHT IN THE UNITED STATES OF AMERICA WITH RESPECT TO OR OTHERWISE ARISING OUT OF OR IN CONNECTION WITH ANY LOAN DOCUMENT BY ANY MEANS PERMITTED BY APPLICABLE
REQUIREMENTS OF LAW, INCLUDING BY THE MAILING THEREOF (BY REGISTERED OR CERTIFIED MAIL, POSTAGE PREPAID) TO THE ADDRESS OF BORROWER SPECIFIED IN SECTION 11.11 (AND SHALL BE EFFECTIVE WHEN SUCH MAILING SHALL BE

  
 155 

 
EFFECTIVE, AS PROVIDED THEREIN). THE BORROWER (AND, TO THE EXTENT SET FORTH IN ANY OTHER LOAN DOCUMENT, EACH OTHER LOAN PARTY) AGREES THAT A FINAL JUDGMENT IN ANY SUCH ACTION OR PROCEEDING SHALL
BE CONCLUSIVE AND MAY BE ENFORCED IN OTHER JURISDICTIONS BY SUIT ON THE JUDGMENT OR IN ANY OTHER MANNER PROVIDED BY LAW. 
 (c)
Non-Exclusive Jurisdiction. Notwithstanding the foregoing, nothing contained in this Section 11.14 (including clause (a) hereof) shall affect the right of any Agent, Lender or L/C Issuer to serve process in any other manner
permitted by applicable Requirements of Law or commence legal proceedings or otherwise proceed against any Loan Party in any other jurisdiction. 

Section 11.15 Waiver of Jury Trial. EACH PARTY HERETO HEREBY IRREVOCABLY WAIVES TRIAL BY JURY IN ANY SUIT, ACTION OR
PROCEEDING WITH RESPECT TO, OR DIRECTLY OR INDIRECTLY ARISING OUT OF, UNDER OR IN CONNECTION WITH, ANY LOAN DOCUMENT OR THE TRANSACTIONS CONTEMPLATED THEREIN OR RELATED THERETO (WHETHER FOUNDED IN CONTRACT, TORT OR ANY OTHER THEORY). EACH PARTY
HERETO (A) CERTIFIES THAT NO OTHER PARTY AND NO RELATED PERSON OF ANY OTHER PARTY HAS REPRESENTED, EXPRESSLY OR OTHERWISE, THAT SUCH OTHER PARTY WOULD NOT, IN THE EVENT OF LITIGATION, SEEK TO ENFORCE THE FOREGOING WAIVER AND
(B) ACKNOWLEDGES THAT IT AND THE OTHER PARTIES HERETO HAVE BEEN INDUCED TO ENTER INTO THE LOAN DOCUMENTS, AS APPLICABLE, BY THE MUTUAL WAIVERS AND CERTIFICATIONS IN THIS SECTION 11.15. 

Section 11.16 Severability. Any provision of any Loan Document being held illegal, invalid or unenforceable in any
jurisdiction shall not affect any part of such provision not held illegal, invalid or unenforceable, any other provision of any Loan Document or any part of such provision in any other jurisdiction. 

Section 11.17 Execution in Counterparts. This Agreement may be executed in any number of counterparts and by different
parties in separate counterparts, each of which when so executed shall be deemed to be an original and all of which taken together shall constitute one and the same agreement. Signature pages may be detached from multiple separate counterparts and
attached to a single counterpart. Delivery of an executed signature page of this Agreement by facsimile transmission or Electronic Transmission shall be as effective as delivery of a manually executed counterpart hereof. 

Section 11.18 Entire Agreement. The Loan Documents embody the entire agreement of the parties and supersede all prior
agreements and understandings relating to the subject matter thereof and any prior letter of interest, commitment letter, fee letter, confidentiality and similar agreements involving any Loan Party and any of the Administrative Agents, any Lender or
any L/C Issuer or any of their respective Affiliates relating to a financing of substantially similar form, purpose or effect. In the event of any conflict between the terms of this Agreement and any other Loan Document, the terms of this Agreement
shall govern (unless such terms of such other Loan Documents are necessary to comply with applicable Requirements of Law, in which case such terms shall govern to the extent necessary to comply therewith). 

Section 11.19 Use of Name. The Borrower agrees, and shall cause each other Loan Party to agree, that it shall not, and none
of its Affiliates shall, issue any press release or other 

  
 156 

 
public disclosure (other than any document filed with any Governmental Authority relating to a public offering of the Securities of any Loan Party) using the name, logo or otherwise referring to
either Administrative Agent or of any of its Affiliates, the Loan Documents or any transaction contemplated therein to which the Secured Parties are party without at least 2 Business Days’ prior notice to the Administrative Agents and
without the prior consent of the Administrative Agents, in each case, except to the extent required to do so under applicable Requirements of Law. 

Section 11.20 Non-Public Information; Confidentiality. (a) The Borrower hereby acknowledges that (a) the
Administrative Agents will make available to the Lenders materials and/or information provided by or on behalf of the Borrower hereunder (collectively, “Borrower Materials”) by posting the Borrower Materials on IntraLinks® or another similar electronic system (the “Platform”) and (b) certain of the Lenders (each, a “Public Lender”) may have personnel who do not wish to receive
material non-public information with respect to the Borrower or its Subsidiaries, or their respective securities, and who may be engaged in investment and other market-related activities with respect to such Persons’ securities. The
Borrower hereby agrees that it will identify that portion of the Borrower Materials that may be distributed to the Public Lenders and that (w) all such Borrower Materials shall be clearly and conspicuously marked “PUBLIC” which, at a
minimum, shall mean that the word “PUBLIC” shall appear prominently on the first page thereof, (x) by marking Borrower Materials “PUBLIC,” the Borrower shall be deemed to have authorized each Agent, the Arrangers and the
Lenders to treat such Borrower Materials as not containing any material non-public information (although it may be sensitive and proprietary) with respect to the Borrower or its Subsidiaries or their respective securities for purposes of United
States Federal and state securities laws, (y) all Borrower Materials marked “PUBLIC” are permitted to be made available through a portion of the Platform designated “Public Side Information” and (z) the Agents and the
Arrangers shall treat the Borrower Materials that are not marked “PUBLIC” as being suitable only for posting on a portion of the Platform not designated “Public Side Information.” Notwithstanding the foregoing provisions of this
paragraph, the Borrower shall be under no obligation to mark the Borrower Materials “PUBLIC.”. 
 (b) Each Lender, Swingline
Lender, each L/C Issuer and each Agent agrees to use all reasonable efforts to maintain, in accordance with its customary practices, the confidentiality of information obtained by it pursuant to any Loan Document concerning the Loan Parties and
their Affiliates and Subsidiaries or otherwise, except that such information may be disclosed (i) with the Borrower’s consent, (ii) to any Agent, any other Lender, any Affiliate of a Lender or any Approved Fund (it being understood
that the Persons to whom such disclosure is made will be informed of the confidential nature of such information and instructed to keep such information confidential), (iii) to Related Persons of such Lender, L/C Issuer or such Agent, as the
case may be, or to any Person that any L/C Issuer causes to Issue Letters of Credit hereunder, in each case, that are advised of the confidential nature of such information and are instructed to keep such information confidential, (iv) to the
extent such information presently is or hereafter becomes available to such Lender, L/C Issuer or such Agent, as the case may be, on a non-confidential basis from a source other than any Loan Party, (v) to the extent disclosure is required by
applicable Requirements of Law, any pending legal, judicial, regulatory or administrative proceeding or as otherwise required by any other legal process or requested or demanded by any Governmental Authority (or self-regulatory authority) (in which
case such Lender, Swingline Lender, L/C Issuer or Agent agrees (except with respect to any audit or examination conducted by auditors or any regulatory authority (including self-regulatory authority) exercising examination

  
 157 

 
or regulatory authority), to the extent practicable and not prohibited by applicable law, to inform you promptly thereof prior to such disclosure), (vi) to the extent such information is
received by such Lender, Swingline Lender, L/C Issuer or Agent or any of its respective Affiliates from a third party that is not, to such Lender’s, Swingline Lender’s, L/C Issuer’s or Agent’s or any of its respective
Affiliates’ knowledge, subject to contractual confidentiality obligations owing to the Borrower, (vii) to the extent that such information is independently developed by such Lender, Swingline Lender, L/C Issuer or Agent or any of its
respective Affiliates, (viii) for purposes of establishing a “due diligence” defense, (ix) to the extent necessary or customary for inclusion in league table measurements or in any tombstone or other advertising materials (and
the Loan Parties consent to the publication of such tombstone or other advertising materials by an Administrative Agent, any Lender, any L/C Issuer or any of their Related Persons), (x) to the National Association of Insurance
Commissioners or any similar organization, any examiner or any nationally recognized rating agency or otherwise to the extent consisting of general portfolio information that does not identify borrowers, (xi) to current or prospective
assignees, SPVs grantees of any option described in Section 11.2(f) or participants, pledgees referred to in Section 11.2(e), direct or indirect (including prospective) contractual counterparties (or their
respective advisors) to any Hedging Agreement permitted hereunder and to their respective Related Persons, in each case to the extent such assignees, participants, pledgees, counterparties or Related Persons agree to be bound by provisions
substantially similar to (or at least as restrictive as) the provisions of this Section 11.20 and (xii) in connection with the exercise of any remedy or the enforcement of any right under this Agreement or any other Loan Document.
In the event of any conflict between the terms of this Section 11.20 and those of any other Contractual Obligation entered into with any Loan Party (whether or not a Loan Document), the terms of this Section 11.20 shall
govern. 
 Section 11.21 Patriot Act Notice. Each Lender subject to the Patriot Act hereby notifies the Borrower and each
other Loan Party that, pursuant to Section 326 thereof, it is required to obtain, verify and record information that identifies the Borrower and each other Loan Party, including the name and address of the Borrower and each other Loan Party and
other information allowing such Lender to identify the Borrower and each other Loan Party in accordance with such act. 

Section 11.22 Senior Indebtedness. The Obligations constitute “Senior Debt” or “Senior Indebtedness”,
as applicable, and “Designated Senior Debt” or “Designated Senior Indebtedness”, as applicable, under, and as defined in, and for the purposes of, the Existing Subordinated Notes Indentures. 

[SIGNATURE PAGES FOLLOW] 

  
 158 

 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be executed by their
respective officers thereunto duly authorized, as of the date first above written. 
  

			
	ALERE INC., as Borrower
		
	By:		 /s/ Jim Hinrichs

	Name:		Jim Hinrichs
	Title:		Chief Financial Officer

  
 [Alere Credit Agreement
Signature Page (2015)] 

 
			
	GOLDMAN SACHS BANK USA, as B Term Loan       Administrative Agent and Lender
		
	By:		 /s/ Charles D. Johnston

	Name:		Charles D. Johnston
	Title:		Authorized Signatory

  
 [Alere Credit Agreement
Signature Page (2015)] 

 
			
	 GENERAL ELECTRIC CAPITAL CORPORATION, as Pro Rata Administrative Agent, Collateral Agent, L/C Issuer and
Lender

		
	By:		 /s/ Daniel L. Evans

	Name:		Daniel L. Evans
	Title:		Duly authorized Signatory

  
 [Alere Credit Agreement
Signature Page (2015)] 

			
	JPMORGAN CHASE BANK, N.A., as a Lender
		
	By:		 /s/ Vanessa Chiu

	Name:		Vanessa Chiu
	Title:		Executive Director

  
 [Alere Credit Agreement
Signature Page (2015)] 

			
	DNB CAPITAL LLC, as Lender
		
	By:		 /s/ Thomas Tangen

	Name:		Thomas Tangen
	Title:		Senior Vice President, Head of Corporate Banking
	
	 DNB BAK ASA, NEW YORK BRANCH, as Co-Documentation Agent

		
	By:		 /s/ Thomas Tangen

	Name:		Thomas Tangen
	Title:		Senior Vice President, Head of Corporate Banking
		
	By:		 /s/ Geshu Sugandh

	Name:		Geshu Sugandh
	Title:		First Vice President

  
 [Alere Credit Agreement
Signature Page (2015)] 

			
	ROYAL BANK OF CANADA, as Lender
		
	By:		 /s/ Dean Sas

	Name:		Dean Sas
	Title:		Authorized Signatory

  
 [Alere Credit Agreement
Signature Page (2015)] 

			
	 HSBC BANK USA, NATIONAL ASSOCIATION, as Lender

		
	By:		 /s/ Elizabeth R. Peck

	Name:		Elizabeth R. Peck
	Title:		Senior Vice President

  
 [Alere Credit Agreement
Signature Page (2015)] 

			
	HSBC BANK, PLC., as Lender
		
	By:		 /s/ Henry Moore

	Name:		Henry Moore
	Title:		Relationship Director

  
 [Alere Credit Agreement
Signature Page (2015)] 

			
	CITIZENS BANK, N.A., as Lender
		
	By:		 /s/ Kathryn McDonough

	Name:		Kathryn McDonough
	Title:		Director

  
 [Alere Credit Agreement
Signature Page (2015)] 

			
	SIEMENS FINANCIAL SERVICES INC., as Lender
		
	By:		 /s/ Maria Levy

	Name:		Maria Levy
	Title:		Vice President
		
	By:		 /s/ Melissa J. Brown

	Name:		Melissa J. Brown
	Title:		Sr. Trans. Cord.

  
 [Alere Credit Agreement
Signature Page (2015)] 

 Exhibit A 

to 
 Credit Agreement

 Form of Assignment 

This Assignment and Assumption Agreement (this “Assignment”) is dated as of the Effective Date (as defined below) and is
entered into between [Insert name of Assignor[s]] (the “Assignor[s]”) and [Insert name of Assignee[s]] (the “Assignee[s]”). Capitalized terms used but not defined herein
shall have the meanings given to them in the Credit Agreement identified and defined below, receipt of a copy of which is hereby acknowledged by the Assignee[s]. The Standard Terms and Conditions set forth in Annex 1 attached hereto
(the “Standard Terms and Conditions”) are hereby agreed to and incorporated herein by reference and made a part of this Assignment as if set forth herein in full. 

For an agreed consideration, the Assignor[s] hereby irrevocably sells and assigns to the Assignee[s], and the Assignee[s] hereby irrevocably
purchases and assumes from the Assignor[s], subject to and in accordance with the Standard Terms and Conditions and the Credit Agreement, as of the Effective Date inserted by the Applicable Administrative Agent as contemplated below, (i) all of
the Assignor[’s] rights and obligations in its capacity as a Lender under the Credit Agreement and any other documents or instruments delivered pursuant thereto to the extent related to the amount and percentage interest identified below of all
of the Assignor[’s] outstanding rights and obligations under the respective facilities identified below (including without limitation any letters of credit, guarantees, and swingline loans included in such facilities), and (ii) to the
extent permitted to be assigned under applicable law, all claims, suits, causes of action and any other right of the Assignor[s] (in [its][their respective] capacity as a Lender) against any Person, whether known or unknown, arising under or in
connection with the Credit Agreement, any other documents or instruments delivered pursuant thereto or the loan transactions governed thereby or in any way based on or related to any of the foregoing, including, but not limited to, contract claims,
tort claims, malpractice claims, statutory claims and all other claims at law or in equity related to the rights and obligations sold and assigned pursuant to clause (i) above (the rights and obligations sold and assigned by the
Assignor[s] to the Assignee[s] pursuant to clauses (i) and (ii) above being referred to herein collectively as the “Assigned Interest”). Such sale and assignment is without recourse to the Assignor[s] and,
except as expressly provided in this Assignment, without representation or warranty by the Assignor[s]. 
  

			
	Assignor[s]:		                    
		
	Assignee[s]:		                    
		
	Borrower:		Alere Inc., a Delaware corporation (the “Borrower”)
		
	[Administrative Agent:		Goldman Sachs Bank USA, as B Term Loan administrative agent (in such capacity and together with its successors and permitted assigns, the “Administrative Agent”)]
		
	[Administrative Agent:		General Electric Capital Corporation, as Pro Rata administrative agent (in such capacity and together with its successors and permitted assigns, the “Administrative Agent”)]
		
	Credit Agreement:		Credit Agreement, dated as of June 18, 2015, among the Borrower, Goldman Sachs Bank USA, as the B Term Loan Administrative Agent, General Electric Capital Corporation, as the Pro Rata Administrative Agent and the Collateral
Agent, the L/C Issuers and the other Secured Parties party thereto (as the same may be amended, restated, supplemented or otherwise modified from time to time, the “Credit Agreement”).
		
	[Trade Date:		            ,         ]1
		
	 Effective Date:
		            ,         

  

	1 	To be completed if the Assignor(s) and the Assignee(s) intend that the minimum assignment amount is to be determined as of the Trade Date. 

																	
	 Assignor
 [(collectively, the

“Assignors”)]
	  	 Assignee [(collectively

the “Assignees”)]
	  	Facility
Assigned2	  	Aggregate amount of
Commitments or
principal amount
of
Loans for all Lenders3	 	  	Aggregate amount of
Commitments or
principal amount of
Loans Assigned4	 	  	Percentage
Assigned5	 
	 [Name of Assignor]
	  	[Name of Assignee]	  		  	$	                    	  	  	$	                    	  	  	 	        .            	% 
	 [Name of Assignor]
	  	[Name of Assignee]	  		  	$	                    	  	  	$	                    	  	  	 	        .            	% 
	 [Name of Assignor]
	  	[Name of Assignee]	  		  	$	                    	  	  	$	                    	  	  	 	        .            	% 

 [THE REMAINDER OF THIS PAGE
WAS INTENTIONALLY LEFT BLANK] 
  

	2 	Fill in the appropriate defined term for the Tranche of Loans and/or Commitments under the Credit Agreement that are being assigned under this Assignment (e.g., “Revolving Credit Commitment”, “A Term
Loans”, “B Term Loans”, etc). 

	3 	In the case of the Revolving Credit Commitment, including Revolving Loans and interests, participations and obligations to participate in Letters of Credit and Swing Loans. 

	4 	Amount to be adjusted by the counterparties to take into account any payments or prepayments made between the Trade Date and the Effective Date. The aggregate amounts are inserted for informational purposes only to help
in calculating the percentages assigned which, themselves, are for informational purposes only. 

	5 	Set forth, to at least 9 decimals, the Assigned Interest as a percentage of the aggregate Commitment or Loans in the respective Facility. This percentage is set forth for informational purposes only and is not intended
to be binding. The assignments are based on the amounts assigned not on the percentages listed in this column. 

 IN WITNESS WHEREOF, the parties hereto have caused this Assignment to be executed by their
respective officers thereunto duly authorized, as of the date first above written. 
  

			
	[NAME OF ASSIGNOR] as Assignor
		
	By:		  

	Name:		
	Title:		
	
	[NAME OF ASSIGNEE] as Assignee
		
	By:		  

	Name:		
	Title:		
	
	Lending Office [for Eurodollar Rate Loans]:
	
	[Insert Address (including contact name, fax number and e-mail address)]
	
	Lending Office (and address for notices) for any other purpose:
	
	[Insert Address (including contact name, fax number and e-mail address)]

 [SIGNATURE PAGE TO ALERE INC. 

ASSIGNMENT AND ASSUMPTION AGREEMENT] 

							
	ACCEPTED and AGREED
this     day of                      :		
		
	 [GOLDMAN SACHS BANK USA,
as B Term Loan Administrative Agent
		
			
	By:		  
		
	Name:				
	Title:]				
		
	 GENERAL ELECTRIC CAPITAL CORPORATION, as Pro Rata Administrative Agent
		
			
	By:		  
		
	Name:				
	Title:]				
		
	[ALERE INC.		
			
	By:		  
		
	Name:				
	Title:]6				
			
			[[NAME OF SWINGLINE LENDER]		
				
			By:		  
		
			Name:				
			Title:				
			
			[NAME OF EACH L/C ISSUER]		
				
			By:		  
		
			Name:				
			Title:]]7				

  
  

	6 	The consent of the Borrower is only required to the extent provided by Section 11.2(b) of the Credit Agreement. 

	7 	The consent of the Swingline Lender and each L/C Issuer is only required to the extent provided in Section 11.2(b) of the Credit Agreement. 

[SIGNATURE PAGE TO ALERE INC. 

ASSIGNMENT AND ASSUMPTION AGREEMENT] 

 ANNEX 1 

STANDARD TERMS AND CONDITIONS 
 FOR
ASSIGNMENT AND ASSUMPTION AGREEMENT 
 Section 1. Representations, Warranties and Covenants of Assignees. [Each][The]
Assignee [severally but not jointly] (a) represents and warrants to its corresponding Assignor and the Applicable Administrative Agent that (i) it has full power and authority, and has taken all actions necessary, for such Assignee to
execute and deliver this Assignment and to consummate the transactions contemplated hereby, (ii) it meets all requirements of an Eligible Assignee under the Credit Agreement and (iii) it is sophisticated with respect to decisions to
acquire assets of the type represented by the Assigned Interest assigned to it hereunder and either such Assignee or the Person exercising discretion in making the decision for such assignment is experienced in acquiring assets of such type,
(b) appoints and authorizes the Administrative Agents and the Collateral Agent to take such action as an administrative agent and collateral agent on its behalf and to exercise such powers under the Loan Documents as are delegated to the
Administrative Agents and/or the Collateral Agent by the terms thereof, together with such powers as are reasonably incidental thereto, (c) shall perform in accordance with their terms all obligations that, by the terms of the Loan Documents,
are required to be performed by it as a Lender, (d) confirms it has received a copy of the Credit Agreement and has received or has been accorded the opportunity to receive copies of the most recent financial statements delivered pursuant to
Section 6.1 thereof, as applicable, and documents and information as it has deemed appropriate to make its own credit analysis and decision to enter into this Assignment, (e) has, independently and without reliance upon any Agent or
any other Lender and based on such documents and information as it has deemed appropriate, made its own credit analysis and decision to enter into this Assignment and to purchase the Assigned Interest and agrees that it will, independently and
without reliance on any Agent and/or Lender, and based on such documents and information as it shall deem appropriate at the time, continue to make its own credit decisions in taking or not taking action under the Loan Documents, (f) specifies
as its applicable lending offices (and addresses for notices) the offices at the addresses set forth beneath its name on the signature pages hereof, (g) shall pay to the Applicable Administrative Agent an assignment fee in the amount of $3,500
to the extent such fee is required to be paid under Section 11.2(c) of the Credit Agreement and (h) to the extent required pursuant to Section 2.17(h) of the Credit Agreement, attaches two completed originals of Forms
W-8ECI, W-8BEN, W-8BEN-E or W-9. 
 Section 2. Determination of Effective Date; Register. Following the due execution and
delivery of this Assignment by [each][the] Assignor, each Assignee and, to the extent required by Section 11.2(b) of the Credit Agreement, the Borrower, this Assignment (including its attachments) will be delivered to the Applicable
Administrative Agent for its acceptance and recording in the applicable Register. The effective date of this Assignment (the “Effective Date”) shall be the later of (i) the acceptance of this Assignment by the Applicable
Administrative Agent and (ii) the recording of this Assignment in the applicable Register. The Applicable Administrative Agent shall insert the Effective Date when known in the space provided therefor at the beginning of this Assignment. 

Section 3. Effect. As of the Effective Date, (a) [each][the] Assignee shall be a party to the Credit Agreement and, to
the extent provided in this Assignment, have the rights and obligations of a Lender under the Credit Agreement and (b) [each][the] Assignor shall, to the extent provided in this Assignment, relinquish its rights (except those surviving the
termination of the Commitments and payment in full of the Obligations) and be released from its obligations under the Loan Documents other than those obligations relating to events and circumstances occurring prior to the Effective Date. 

Section 4. Distribution of Payments. From and after the Effective Date, the Applicable Administrative Agent shall make all
payments under the Loan Documents in respect of [the][each] Assigned Interest (including payments of principal, interest, fees and other amounts) to [the][the relevant] 

 
Assignor for amounts which have accrued to but excluding the Effective Date and to [the][the relevant] Assignee for amounts which have accrued from and after the Effective Date. Notwithstanding
the foregoing, the Applicable Administrative Agent shall make all payments of interest, fees or other amounts paid or payable in kind from and after the Effective Date to [the][the relevant] Assignee. 

Section 5. Miscellaneous. This Assignment is a Loan Document and, as such, is subject to certain provisions of the Credit
Agreement, including Sections 1.5, 11.14(a) and 11.15 thereof. On and after the Effective Date, this Assignment shall be binding upon, and inure to the benefit of, the Assignors, Assignees, the Administrative Agent and their
Related Persons and their respective successors and assigns. THIS ASSIGNMENT SHALL BE GOVERNED BY, AND BE CONSTRUED AND INTERPRETED IN ACCORDANCE WITH, THE LAW OF THE STATE OF NEW YORK. This Assignment may be executed in any number of counterparts
and by different parties in separate counterparts, each of which when so executed shall be deemed to be an original and all of which taken together shall constitute one and the same agreement. Signature pages may be detached from multiple separate
counterparts and attached to a single counterpart. Delivery of an executed signature page of this Assignment by facsimile transmission or Electronic Transmission shall be as effective as delivery of a manually executed counterpart of this
Assignment. 

 EXHIBIT B-1 

TO 

CREDIT AGREEMENT 

Form of A TERM LOAN Note 
  

					
	Lender: [NAME OF LENDER]	 	 	  	New York, New York
	Principal Amount: $                    	 		  	[            ], 2015

 FOR VALUE RECEIVED, the undersigned, Alere Inc., a Delaware corporation (the “Borrower”),
hereby promises to pay to the order of the Lender set forth above or its registered assigns (the “Lender”) the Principal Amount set forth above, or, if less, the aggregate unpaid principal amount of the A Term Loans (as defined in
the Credit Agreement referred to below) of the Lender to the Borrower, payable at such times and in such amounts as are specified in the Credit Agreement. 

The Borrower promises to pay interest on the unpaid principal amount of the A Term Loans from the date made until such principal amount is
paid in full, payable at such times and at such interest rates as are specified in the Credit Agreement. Demand, diligence, presentment, protest and notice of non-payment and protest are hereby waived by the Borrower. 

Both principal and interest are payable in Dollars to General Electric Capital Corporation, as the Pro Rata Administrative Agent, at
                    , in immediately available funds. 

This Note is one of the Notes referred to in, and is entitled to the benefits of, the Credit Agreement, dated as of June 18, 2015, among
the Borrower, Goldman Sachs Bank USA, as the B Term Loan Administrative Agent, General Electric Capital Corporation, as the Pro Rata Administrative Agent and the Collateral Agent, the L/C Issuers and the other Secured Parties party thereto (as the
same may be amended, restated, supplemented or otherwise modified from time to time, the “Credit Agreement”). 
 The Credit
Agreement, among other things, (a) provides for the making of A Term Loans by the Lender to the Borrower in an aggregate amount equal to the Principal Amount set forth above, the indebtedness of the Borrower resulting from such A Term Loans
being evidenced by this Note and (b) contains provisions for acceleration of the maturity of the unpaid principal amount of this Note upon the happening of certain stated events and also for prepayments on account of the principal hereof prior
to the maturity hereof upon the terms and conditions specified therein. 
 This Note is a Loan Document, is entitled to the benefits of the
Loan Documents and is subject to certain provisions of the Credit Agreement, including Sections 1.5, 11.14(a) and 11.15 thereof. 

This Note is a registered obligation, transferable only upon notation in the Register for the A Term Loans, and no assignment hereof shall be
effective until recorded therein. 
 THIS NOTE SHALL BE GOVERNED BY, AND CONSTRUED AND INTERPRETED IN ACCORDANCE WITH, THE LAW OF THE STATE
OF NEW YORK. 
 [SIGNATURE PAGES FOLLOW] 

 IN WITNESS WHEREOF, the Borrower has caused this Note to be executed and delivered by its duly
authorized officer as of the day and year and at the place set forth above. 
  

			
	ALERE INC.
		
	By:		  

	Name:		
	Title:		

 [SIGNATURE PAGE TO ALERE INC. 

A TERM LOAN PROMISSORY NOTE] 

 EXHIBIT B-2 

TO 

CREDIT AGREEMENT 

Form of B TERM LOAN Note 
  

					
	Lender: [NAME OF LENDER]				New York, New York
	Principal Amount: $        				[            ], 2015

 FOR VALUE RECEIVED, the undersigned, Alere Inc., a Delaware corporation (the “Borrower”),
hereby promises to pay to the order of the Lender set forth above or its registered assigns (the “Lender”) the Principal Amount set forth above, or, if less, the aggregate unpaid principal amount of all the B Term Loans (as defined
in the Credit Agreement referred to below) of the Lender to the Borrower, payable at such times and in such amounts as are specified in the Credit Agreement. 

The Borrower promises to pay interest on the unpaid principal amount of the B Term Loans from the date made until such principal amount is
paid in full, payable at such times and at such interest rates as are specified in the Credit Agreement. Demand, diligence, presentment, protest and notice of non-payment and protest are hereby waived by the Borrower. 

Both principal and interest are payable in Dollars to Goldman Sachs Bank USA, as B Term Loan Administrative Agent, at
                    , in immediately available funds. 

This Note is one of the Notes referred to in, and is entitled to the benefits of, the Credit Agreement, dated as of June 18, 2015, among
the Borrower, Goldman Sachs Bank USA, as the B Term Loan Administrative Agent, General Electric Capital Corporation, as the Pro Rata Administrative Agent and the Collateral Agent, the L/C Issuers and the other Secured Parties party thereto (as the
same may be amended, restated, supplemented or otherwise modified from time to time, the “Credit Agreement”). 
 The Credit
Agreement, among other things, (a) provides for the making of B Term Loans by the Lender to the Borrower in an aggregate amount equal to the Principal Amount set forth above, the indebtedness of the Borrower resulting from such B Term Loans
being evidenced by this Note and (b) contains provisions for acceleration of the maturity of the unpaid principal amount of this Note upon the happening of certain stated events and also for prepayments on account of the principal hereof prior
to the maturity hereof upon the terms and conditions specified therein. 
 This Note is a Loan Document, is entitled to the benefits of the
Loan Documents and is subject to certain provisions of the Credit Agreement, including Sections 1.5, 11.14(a) and 11.15 thereof. 

This Note is a registered obligation, transferable only upon notation in the Register for the B Term Loans, and no assignment hereof shall be
effective until recorded therein. 
 THIS NOTE SHALL BE GOVERNED BY, AND CONSTRUED AND INTERPRETED IN ACCORDANCE WITH, THE LAW OF THE STATE
OF NEW YORK. 
 [SIGNATURE PAGES FOLLOW] 

 IN WITNESS WHEREOF, the Borrower has caused this Note to be executed and delivered by its duly
authorized officer as of the day and year and at the place set forth above. 
  

			
	ALERE INC.
		
	By:		  

	Name:		
	Title:		

 [SIGNATURE PAGE TO ALERE INC. 

B TERM LOAN PROMISSORY NOTE] 

 EXHIBIT B-3 

TO 
 CREDIT AGREEMENT

 Form of INCREMENTAL TERM NOTe 
  

			
	Lender: [NAME OF LENDER]		New York, New York
	Principal Amount: $        		[            ], 20[    ]

 FOR VALUE RECEIVED, the undersigned, Alere Inc., a Delaware corporation (the “Borrower”),
hereby promises to pay to the order of the Lender set forth above or its registered assigns (the “Lender”) on [            ], 20     (the
“Incremental Term Loan Maturity Date”) the Principal Amount set forth above, or, if less, the aggregate unpaid principal amount of all [insert the applicable description of the respective Tranche of Incremental Term Loans] (as
defined in the Credit Agreement referred to below) of the Lender to the Borrower, payable at such times and in such amounts as are specified in the Credit Agreement. 

The Borrower promises to pay interest on the unpaid principal amount of each [Incremental Term Loan] from the date made until such principal
amount is paid in full, payable at such times and at such interest rates as are specified in the Credit Agreement. Demand, diligence, presentment, protest and notice of non-payment and protest are hereby waived by the Borrower. 

Both principal and interest are payable in Dollars to Goldman Sachs Bank USA, as the B Term Loan Administrative Agent, at
                    , in immediately available funds. 

This Note is one of the Notes referred to in, and is entitled to the benefits of, the Credit Agreement, dated as of June 18, 2015, among
the Borrower, Goldman Sachs Bank USA, as the B Term Loan Administrative Agent, General Electric Capital Corporation, as the Pro Rata Administrative Agent and the Collateral Agent, the L/C Issuers and the other Secured Parties party thereto (as the
same may be amended, restated, supplemented or otherwise modified from time to time, the “Credit Agreement”). 
 The Credit
Agreement, among other things, (a) provides for the making of [Incremental Term Loans] by the Lender to the Borrower in an aggregate amount equal to the Principal Amount set forth above, the indebtedness of the Borrower resulting from such
[Incremental Term Loans] being evidenced by this Note and (b) contains provisions for acceleration of the maturity of the unpaid principal amount of this Note upon the happening of certain stated events and also for prepayments on account of
the principal hereof prior to the maturity hereof upon the terms and conditions specified therein. 
 This Note is a Loan Document, is
entitled to the benefits of the Loan Documents and is subject to certain provisions of the Credit Agreement, including Sections 1.5, 11.14(a) and 11.15 thereof. 

This Note is a registered obligation, transferable only upon notation in the Register for the Incremental Term Loans, and no assignment hereof
shall be effective until recorded therein. 
 THIS NOTE SHALL BE GOVERNED BY, AND CONSTRUED AND INTERPRETED IN ACCORDANCE WITH, THE LAW OF
THE STATE OF NEW YORK. 

 IN WITNESS WHEREOF, the Borrower has caused this Note to be executed and delivered by its duly
authorized officer as of the day and year and at the place set forth above. 
  

			
	ALERE INC.
		
	By:		  

	Name:		
	Title:		

 [SIGNATURE PAGE TO ALERE INC. 

INCREMENTAL TERM LOAN PROMISSORY NOTE] 

 EXHIBIT B-4 

TO 

CREDIT AGREEMENT 

Form of Revolving LOAN Note 
  

					
	Lender: [NAME OF LENDER]		 	New York, New York	  
	Principal Amount: $        		 	            ,         	  

 FOR VALUE RECEIVED, the undersigned, Alere Inc., a Delaware corporation (the “Borrower”),
hereby promises to pay to the order of the Lender set forth above or its registered assigns (the “Lender”) the Principal Amount set forth above, or, if less, the aggregate unpaid principal amount of all Revolving Loans (as defined
in the Credit Agreement referred to below) of the Lender to the Borrower, payable at such times and in such amounts as are specified in the Credit Agreement. 

The Borrower promises to pay interest on the unpaid principal amount of each Revolving Loan from the date made until such principal amount is
paid in full, payable at such times and at such interest rates as are specified in the Credit Agreement. Demand, diligence, presentment, protest and notice of non-payment and protest are hereby waived by the Borrower. 

Both principal and interest are payable in Dollars to General Electric Capital Corporation, as the Pro Rata Administrative Agent, at
                    , in immediately available funds. 

This Note is one of the Notes referred to in, and is entitled to the benefits of, the Credit Agreement, dated as of June 18, 2015, among
the Borrower, Goldman Sachs Bank USA, as the B Term Loan Administrative Agent, General Electric Capital Corporation, as the Pro Rata Administrative Agent and the Collateral Agent, the L/C Issuers and the other Secured Parties party thereto (as the
same may be amended, restated, supplemented or otherwise modified from time to time, the “Credit Agreement”). 
 The Credit
Agreement, among other things, (a) provides for the making of Revolving Loans by the Lender to the Borrower in an aggregate amount not to exceed at any time outstanding the Principal Amount set forth above, the indebtedness of the Borrower
resulting from such Revolving Loans being evidenced by this Note and (b) contains provisions for acceleration of the maturity of the unpaid principal amount of this Note upon the happening of certain stated events and also for prepayments on
account of the principal hereof prior to the maturity hereof upon the terms and conditions specified therein. 
 This Note is a Loan
Document, is entitled to the benefits of the Loan Documents and is subject to certain provisions of the Credit Agreement, including Sections 1.5, 11.14(a) and 11.15 thereof. 

This Note is a registered obligation, transferable only upon notation in the Register for the Revolving Loans, and no assignment hereof shall
be effective until recorded therein. 
 THIS NOTE SHALL BE GOVERNED BY, AND CONSTRUED AND INTERPRETED IN ACCORDANCE WITH, THE LAW OF THE
STATE OF NEW YORK. 
 [SIGNATURE PAGES FOLLOW] 

 IN WITNESS WHEREOF, the Borrower has caused this Note to be executed and delivered by its duly
authorized officer as of the day and year and at the place set forth above. 
  

			
	ALERE INC.
		
	By:		  

	Name:		
	Title:		

 [SIGNATURE PAGE TO ALERE INC. REVOLVING LOAN PROMISSORY NOTE] 

 EXHIBIT C 

TO 

CREDIT AGREEMENT 

Form of Notice of Borrowing 
 [GENERAL
ELECTRIC CAPITAL CORPORATION, 
       as Pro Rata Administrative Agent] 

[GOLDMAN SACHS BANK USA, 
       as
B Term Loan Administrative Agent] under the 
       Credit Agreement referred to below 

            ,          

Attention: 
  

	 	Re:	ALERE INC. (the “Borrower”) 

 Reference is made to the Credit Agreement, dated
as of June 18, 2015, among the Borrower, Goldman Sachs Bank USA, as the B Term Loan Administrative Agent, General Electric Capital Corporation, as the Pro Rata Administrative Agent and the Collateral Agent, the L/C Issuers and the other Secured
Parties party thereto (as the same may be amended, restated, supplemented or otherwise modified from time to time, the “Credit Agreement”). Unless otherwise defined herein, terms defined in the Credit Agreement and used herein shall
have the meanings given to them in the Credit Agreement. 
 The Borrower hereby gives you irrevocable notice, pursuant to
Section 2.2 of the Credit Agreement of its request of a Borrowing (the “Proposed Borrowing”) under the Credit Agreement and, in that connection, sets forth the following information: 

A. The Business Day of the Proposed Borrowing is             ,
         (the “Funding Date”). 
 [B. The aggregate principal amount
of Revolving Loans requested is $        , of which $         consists of [Base Rate Loans] [and] [$         consists of
Eurodollar Rate Loans having an initial Interest Period of      months.]] 
 [[B.][C.] The aggregate
principal amount of [A Term Loans][B Term Loans] [Designate Tranche of Incremental Term Loans or Specified Refinancing Term Loans] requested is $        , of which
[$         consists of Base Rate Loans] [and][$         consists of Eurodollar Rate Loans having an initial Interest Period of      months.]] 

The undersigned hereby certifies that the following statements are true on the date hereof, and will be true on the Funding Date, both before
and after giving effect to the Proposed Borrowing and any other Loan to be made or Letter of Credit to be Issued on or before the Funding Date: 

[(i) the representations and warranties set forth in the Loan Documents are true and correct in all material respects (or in
all respects to the extent that any such representation or warranty is qualified by materiality or Material Adverse Effect), as though made on and as of such Funding Date, except to the extent such representations and warranties expressly relate to
an earlier date, in which case such representations and warranties were true and correct as of such earlier date; and 

 (ii) no Default or Event of Default is continuing.]1 
  

			
	ALERE INC.
		
	By:		  

	Name:		
	Title:		

  

	1 	To be modified in the case of the incurrence of Term Loans for a Limited Condition Acquisition to the extent agreed to in the respective Incremental Amendment. 

  
 [SIGNATURE PAGE TO
NOTICE OF BORROWING DATED             ,         ] 

 EXHIBIT D 

TO 

CREDIT AGREEMENT 

Form of Swing Loan Request 
 GENERAL
ELECTRIC CAPITAL CORPORATION, 
       as Pro Rata Administrative Agent under the 

      Credit Agreement referred to below 

Attention: 

            ,          

 

	 	Re:	ALERE INC. (the “Borrower”) 

 Reference is made to the Credit Agreement, dated
as of June 18, 2015, among the Borrower, Goldman Sachs Bank USA, as the B Term Loan Administrative Agent, General Electric Capital Corporation, as the Pro Rata Administrative Agent and the Collateral Agent, the L/C Issuers and the other Secured
Parties party thereto (as the same may be amended, restated, supplemented or otherwise modified from time to time, the “Credit Agreement”). Unless otherwise defined herein, terms defined in the Credit Agreement and used herein shall
have the meanings given to them in the Credit Agreement. 
 The Borrower hereby gives you irrevocable notice pursuant to
Section 2.3 of the Credit Agreement that it requests Swing Loans under the Credit Agreement (the “Proposed Advance”) and, in that connection, sets for the following information: 

A. The Business Day of the Proposed Advance is             ,
         (the “Funding Date”). 
 B. The aggregate principal amount
of Swing Loan requested is $        . 
 The undersigned hereby certifies that the following
statements are true on the date hereof, and will be true on the Funding Date, both before and after giving effect to the Proposed Advance and any other Loan to be made or Letter of Credit to be issued on or before the Funding Date: 

(i) the representations and warranties set forth in the Loan Documents are true and correct in all material respects (or in all
respects to the extent that any such representation or warranty is qualified by materiality or Material Adverse Effect) with the same effect as though made on and as of such Funding Date, except to the extent such representations and warranties
expressly relate to an earlier date, in which case such representations and warranties were true and correct as of such earlier date and 

(ii) no Default or Event of Default is continuing. 

			
	ALERE INC.
		
	By:		  

	Name:		
	Title:		

 [SIGNATURE PAGE TO NOTICE OF BORROWING DATED
            ,         ] 

 Exhibit E 

to 
 Credit Agreement

 Form of Letter of Credit Request 

[NAME OF L/C ISSUER], as L/C Issuer 
 under the Credit Agreement
referred to below 
 Attention: 

            ,          

 

	 	Re:	ALERE INC. (the “Borrower”) 

 Reference is made to the Credit Agreement, dated
as of June 18, 2015, among the Borrower, Goldman Sachs Bank USA, as the B Term Loan Administrative Agent, General Electric Capital Corporation, as the Pro Rata Administrative Agent and the Collateral Agent, the L/C Issuers and the other Secured
Parties party thereto (as the same may be amended, restated, supplemented or otherwise modified from time to time, the “Credit Agreement”). Unless otherwise defined herein, terms defined in the Credit Agreement and used herein shall
have the meanings given to them in the Credit Agreement. 
 The Borrower hereby gives you notice, irrevocably, pursuant to
Section 2.4(b) of the Credit Agreement, of its request for your Issuance of a Letter of Credit, in the form attached hereto, for the benefit of [Name of Beneficiary], in the amount of $        , to
be issued on             ,          (the “Issue Date”) with an expiration date of
            ,         . 
 The
undersigned hereby certifies that the following statements are true on the date hereof, and will be true on the Issue Date, both before and after giving effect to the Issuance of the Letter of Credit requested above and any Loan to be made or any
other Letter of Credit to be Issued on or before the Issue Date: 
 (i) the representations and warranties set forth in the
Loan Documents are true and correct in all material respects (or in all respects to the extent that any such representation or warranty is qualified by materiality or Material Adverse Effect), with the same effect as though made on and as of such
Issue Date, except to the extent such representations and warranties expressly relate to an earlier date, in which case such representations and warranties were true and correct as of such earlier date and 

(ii) no Default or Event of Default is continuing. 

Copies of all documentation with respect to the supported transaction are attached hereto. 

 

			
	ALERE INC.
		
	By:		  

	Name:		
	Title:		

  
 E-1 

 EXHIBIT F 

TO 

CREDIT AGREEMENT 

Form of Notice of Conversion or Continuation 

[GENERAL ELECTRIC CAPITAL CORPORATION, 

      as Pro Rata Administrative Agent] 

[GOLDMAN SACHS BANK USA, 
       as
B Term Loan Administrative Agent] under the 
       Credit Agreement referred to below 

            ,          

Attention: 
  

	 	Re:	ALERE INC. (the “Borrower”) 

 Reference is made to the Credit Agreement, dated
as of June 18, 2015, among the Borrower, Goldman Sachs Bank USA, as the B Term Loan Administrative Agent, General Electric Capital Corporation, as the Pro Rata Administrative Agent and the Collateral Agent, the L/C Issuers and the other Secured
Parties party thereto (as the same may be amended, restated, supplemented or otherwise modified from time to time, the “Credit Agreement”). Unless otherwise defined herein, terms defined in the Credit Agreement and used herein shall
have the meanings given to them in the Credit Agreement. 
 The Borrower hereby gives you irrevocable notice, pursuant to
Section 2.10 of the Credit Agreement of its request for the following: 
 [(i) a continuation, on
            ,         , as Eurodollar Rate Loans having an Interest Period of      months of [A Term Loans][B Term
Loans][Designate other Tranche of Term Loans][Revolving Loans] in an aggregate outstanding principal amount of $         having an Interest Period ending on the proposed date for such continuation;] 

[[(i)](ii)] a conversion, on             ,
        , to Eurodollar Rate Loans having an Interest Period of     months of [A Term Loans][B Term Loans][Designate other Tranche of Term Loans][Revolving Loans] in an aggregate
outstanding principal amount of $        ; and] 
 [(i)][(ii)][(iii)] a conversion,
on             ,         , to Base Rate Loans, of [A Term Loans][B Term Loans][Designate other Tranche of Term Loans][Revolving Loans] in an
aggregate outstanding principal amount of $        .] 
 In connection herewith, the undersigned
hereby certifies that no Default or Event of Default is continuing on the date hereof, both before and after giving effect to any Loan to be made or Letter of Credit to be issued on or before any date for any proposed conversion or continuation set
forth above (it being understood that no conversion or continuation requested herein shall constitute the making of any Loan). 
  

			
	ALERE INC.
		
	By:		  

	Name:		
	Title:		

 EXHIBIT I-1 

FORM OF 
 U.S. TAX COMPLIANCE
CERTIFICATE 
 (For Foreign Participants That Are Not Partnerships for U.S. Federal Income Tax Purposes) 

Reference is made to the Credit Agreement, dated as of June 18, 2015, among the Borrower, Goldman Sachs Bank USA, as the B Term Loan
Administrative Agent, General Electric Capital Corporation, as the Pro Rata Administrative Agent and the Collateral Agent, the L/C Issuers and the other Secured Parties party thereto (as the same may be amended, restated, supplemented or otherwise
modified from time to time, the “Credit Agreement”). Unless otherwise defined herein, terms defined in the Credit Agreement and used herein shall have the meanings given to them in the Credit Agreement. 

Pursuant to the provisions of Section 11.2(f) and Section 2.17(h) of the Credit Agreement, the undersigned hereby
certifies that (i) it is the sole record and beneficial owner of the participation in respect of which it is providing this certificate, (ii) it is not a bank extending credit pursuant to a loan agreement entered into in the ordinary
course of its trade or business within the meaning of Section 881(c)(3)(A) of the Code, (iii) it is not a ten percent shareholder of the Borrower within the meaning of Section 871(h)(3)(B) of the Code, and (iv) it is not a
controlled foreign corporation related to the Borrower as described in Section 881(c)(3)(C) of the Code. 
 The undersigned has
furnished its participating Lender with a certificate of its non-U.S. Person status on IRS Form W-8BEN or W-8BEN-E, as applicable. By executing this certificate, the undersigned agrees that (1) if
the information provided on this certificate changes, the undersigned shall promptly so inform such Lender in writing, and (2) the undersigned shall have at all times furnished such Lender with a properly completed and currently effective
certificate in either the calendar year in which each payment is to be made to the undersigned, or in either of the two calendar years preceding such payments.
  

			
	[NAME OF PARTICIPANT]
		
	By:		  

	Name:		
	Title:		

 Date:             , 20[    ] 

 EXHIBIT I-2 

FORM OF 
 U.S. TAX COMPLIANCE
CERTIFICATE 
 (For Foreign Participants That Are Partnerships for U.S. Federal Income Tax Purposes) 

Reference is made to the Credit Agreement, dated as of June 18, 2015, among the Borrower, Goldman Sachs Bank USA, as the B Term Loan
Administrative Agent, General Electric Capital Corporation, as the Pro Rata Administrative Agent and the Collateral Agent, the L/C Issuers and the other Secured Parties party thereto (as the same may be amended, restated, supplemented or otherwise
modified from time to time, the “Credit Agreement”). Unless otherwise defined herein, terms defined in the Credit Agreement and used herein shall have the meanings given to them in the Credit Agreement. 

Pursuant to the provisions of Section 11.2(f) and Section 2.17(h) of the Credit Agreement, the undersigned hereby
certifies that (i) it is the sole record owner of the participation in respect of which it is providing this certificate, (ii) its direct or indirect partners/members are the sole beneficial owners of such participation,
(iii) with respect such participation, neither the undersigned nor any of its direct or indirect partners/members is a bank extending credit pursuant to a loan agreement entered into in the ordinary course of its trade or business within
the meaning of Section 881(c)(3)(A) of the Code, (iv) none of its direct or indirect partners/members is a ten percent shareholder of the Borrower within the meaning of Section 871(h)(3)(B) of the Code and (v) none of its
direct or indirect partners/members is a controlled foreign corporation related to the Borrower as described in Section 881(c)(3)(C) of the Code. 

The undersigned has furnished its participating Lender with IRS Form W-8IMY accompanied by one of the following forms from each of its
partners/members that is claiming the portfolio interest exemption: (i) an IRS Form W-8BEN or W-8BEN-E, as applicable, or (ii) an IRS Form W-8IMY accompanied by an IRS Form W-8BEN or W-8BEN-E, as applicable, from each of such
partner’s/member’s beneficial owners that is claiming the portfolio interest exemption. By executing this certificate, the undersigned agrees that (1) if the information provided on this certificate changes, the undersigned shall
promptly so inform such Lender and (2) the undersigned shall have at all times furnished such Lender with a properly completed and currently effective certificate in either the calendar year in which each payment is to be made to the
undersigned, or in either of the two calendar years preceding such payments. 
  

			
	[NAME OF PARTICIPANT]
		
	By:		  

	Name:		
	Title:		

 Date:             , 20[    ] 

 EXHIBIT I-3 

FORM OF 
 U.S. TAX COMPLIANCE
CERTIFICATE 
 (For Foreign Lenders That Are Partnerships for U.S. Federal Income Tax Purposes) 

Reference is made to the Credit Agreement, dated as of June 18, 2015, among the Borrower, Goldman Sachs Bank USA, as the B Term Loan
Administrative Agent, General Electric Capital Corporation, as the Pro Rata Administrative Agent and the Collateral Agent, the L/C Issuers and the other Secured Parties party thereto (as the same may be amended, restated, supplemented or otherwise
modified from time to time, the “Credit Agreement”). Unless otherwise defined herein, terms defined in the Credit Agreement and used herein shall have the meanings given to them in the Credit Agreement. 

Pursuant to the provisions of Section 2.17(h) of the Credit Agreement, the undersigned hereby certifies that (i) it is the
sole record owner of the Loan(s) (as well as any Note(s) evidencing such Loan(s)) in respect of which it is providing this certificate, (ii) its direct or indirect partners/members are the sole beneficial owners of such Loan(s) (as well as
any Note(s) evidencing such Loan(s)), (iii) with respect to the extension of credit pursuant to this Credit Agreement or any other Loan Document, neither the undersigned nor any of its direct or indirect partners/members is a bank extending
credit pursuant to a loan agreement entered into in the ordinary course of its trade or business within the meaning of Section 881(c)(3)(A) of the Code, (iv) none of its direct or indirect partners/members is a ten percent shareholder
of the Borrower within the meaning of Section 871(h)(3)(B) of the Code and (v) none of its direct or indirect partners/members is a controlled foreign corporation related to the Borrower as described in Section 881(c)(3)(C) of
the Code. 
 The undersigned has furnished the Applicable Administrative Agent and the Borrower with IRS Form W-8IMY accompanied by one of
the following forms from each of its partners/members that is claiming the portfolio interest exemption: (i) an IRS Form W-8BEN or W-8BEN-E, as applicable, or (ii) an IRS Form W-8IMY accompanied by an IRS Form W-8BEN or W-8BEN-E, as applicable, from each of such partner’s/member’s beneficial owners that is claiming the portfolio interest exemption. By executing this certificate, the undersigned agrees that (1) if the
information provided on this certificate changes, the undersigned shall promptly so inform the Borrower and the Applicable Administrative Agent, and (2) the undersigned shall have at all times furnished the Borrower and the Applicable
Administrative Agent with a properly completed and currently effective certificate in either the calendar year in which each payment is to be made to the undersigned, or in either of the two calendar years preceding such payments. 

 

			
	[NAME OF LENDER]
		
	By:		  

	Name:		
	Title:		

 Date:             , 20[    ] 

 EXHIBIT I-4 

FORM OF 
 U.S. TAX COMPLIANCE
CERTIFICATE 
 (For Foreign Lenders That Are Not Partnerships for U.S. Federal Income Tax Purposes) 

Reference is made to the Credit Agreement, dated as of June 18, 2015, among the Borrower, Goldman Sachs Bank USA, as the B Term Loan
Administrative Agent, General Electric Capital Corporation, as the Pro Rata Administrative Agent and the Collateral Agent, the L/C Issuers and the other Secured Parties party thereto (as the same may be amended, restated, supplemented or otherwise
modified from time to time, the “Credit Agreement”). Unless otherwise defined herein, terms defined in the Credit Agreement and used herein shall have the meanings given to them in the Credit Agreement. 

Pursuant to the provisions of Section 2.17(h) of the Credit Agreement, the undersigned hereby certifies that (i) it is the
sole record and beneficial owner of the Loan(s) (as well as any Note(s) evidencing such Loan(s)) in respect of which it is providing this certificate, (ii) it is not a bank extending credit pursuant to a loan agreement entered into in the
ordinary course of its trade or business within the meaning of Section 881(c)(3)(A) of the Code, (iii) it is not a ten percent shareholder of the Borrower within the meaning of Section 871(h)(3)(B) of the Code and (iv) it is not
a controlled foreign corporation related to the Borrower as described in Section 881(c)(3)(C) of the Code. 
 The undersigned has
furnished the Applicable Administrative Agent and the Borrower with a certificate of its non-U.S. Person status on IRS Form W-8BEN or W-8BEN-E, as applicable. By executing this certificate, the undersigned agrees that (1) if the information
provided on this certificate changes, the undersigned shall promptly so inform the Borrower and the Applicable Administrative Agent, and (2) the undersigned shall have at all times furnished the Borrower and the Applicable Administrative Agent
with a properly completed and currently effective certificate in either the calendar year in which each payment is to be made to the undersigned, or in either of the two calendar years preceding such payments. 

 

			
	[NAME OF LENDER]
		
	By:		  

	Name:		
	Title:		

 Date:             , 20[    ]

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00246-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00246-of-00352.parquet"}]]