Document:

<PAGE>

                                                                   EXHIBIT 10.13

                     SCHEDULE IDENTIFYING OMITTED DOCUMENTS

The only particulars in which the attached agreement differs from the omitted
agreements are the name of the officer who is a party to the agreement, the
annual base salary, the amount of severance, the amount of change of control
severance.

<TABLE>
<CAPTION>
                                            Change of
                     Annual                  Control
      Name        Base Salary   Severance   Severance
---------------   -----------   ---------   ---------
<S>               <C>           <C>         <C>
Rodger A. Brown   $   115,000   $ 115,000   $ 230,000
Brent L. Larson   $   135,000   $ 135,000   $ 270,000
</TABLE>

<PAGE>

                              EMPLOYMENT AGREEMENT

     This Employment Agreement is made and entered into effective as of January
1, 2004 (the "Effective Date"), by and between NEOPROBE CORPORATION, a Delaware
Corporation with a place of business at 425 Metro Place North, Suite 300,
Dublin, Ohio 43017-1367 (the "Company") and CARL M. BOSCH of Worthington, Ohio
(the "Employee").

     WHEREAS, the Company and the Employee entered into an Employment Agreement
effective as of April 1, 2000 (the "2000 Employment Agreement"); and

     WHEREAS, the Company and the Employee entered into an Employment Agreement
effective as of October 1, 2001 (the "2001 Employment Agreement"); and

     WHEREAS, the Company and the Employee entered amended the 2001 Employment
Agreement on August 1, 2002 (the "2001 Amendment");

     WHEREAS, the Company and the Employee entered into an Employment Agreement
effective as of February 1, 2003 (the "2003 Employment Agreement"); and

     WHEREAS, the Company and the Employee wish to establish new terms,
covenants, and conditions for the Employee's continued employment with the
Company through this agreement ("Employment Agreement").

     NOW, THEREFORE, in consideration of the mutual agreements herein set forth,
the parties hereto agree as follows:

     1.   DUTIES. From and after the Effective Date, and based upon the terms
          and conditions set forth herein, the Company agrees to employ the
          Employee and the Employee agrees to be employed by the Company, as
          Vice-President, Instrument Development and Operations of the Company
          and in such equivalent, additional or higher executive level position
          or positions as shall be assigned to him by the Company's President
          and CEO. While serving in such executive level position or positions,
          the Employee shall report to, be responsible to, and shall take
          direction from the President and CEO of the Company. During the Term
          of this Employment Agreement (as defined in Section 2 below), the
          Employee agrees to devote substantially all of his working time to the
          position he holds with the Company and to faithfully, industriously,
          and to the best of his ability, experience and talent, perform the
          duties that are assigned to him. The Employee shall observe and abide
          by the reasonable corporate policies and decisions of the Company in
          all business matters disclosed to employee.

          The Employee represents and warrants to the Company that Exhibit A
          attached hereto sets forth a true and complete list of (a) all
          offices, directorships and other positions held by the Employee in
          corporations and firms other than the Company and its subsidiaries and
          (b) any investment or ownership interest in any corporation or firm
          other than the Company beneficially owned by the Employee (excluding
          investments in life insurance policies, bank deposits, publicly traded
          securities that are less than five percent (5%) of their class and
          real estate). The Employee will promptly notify the Board of Directors
          of the Company of any additional positions undertaken or investments
          made by the Employee during the Term of this Employment Agreement if
          they are of a type that if they had existed on the date hereof, should
          have been listed on Exhibit A hereto. As long as the Employee's other
          positions or investments in other firms do not create a conflict of
          interest, violate the Employee's obligations under Section 7 below or
          cause the Employee to neglect his duties hereunder, such activities
          and positions shall not be deemed to be a breach of this Employment
          Agreement.

                                       -2-

<PAGE>

     2.   TERM OF THIS EMPLOYMENT AGREEMENT. Subject to Sections 4 and 5 hereof,
          the Term of this Employment Agreement shall be for a period of twelve
          (12) months, commencing January 1, 2004 and terminating December 31,
          2004.

     3.   COMPENSATION. During the Term of this Employment Agreement, the
          Company shall pay, and the Employee agrees to accept as full
          consideration for the services to be rendered by the Employee
          hereunder, compensation consisting of the following:

          A.   SALARY. Beginning on the first day of the Term of this Employment
               Agreement, the Company shall pay the Employee a salary of One
               Hundred Thirty-Five Thousand Dollars ($135,000) per year, payable
               in semi-monthly or monthly installments as requested by the
               Employee. Further, the Company agrees to review the Employee's
               base salary by July 1, 2004.

          B.   BONUS. The Compensation Committee of the Board of Directors will,
               on an annual basis, review the performance of the Company and of
               the Employee and will pay such bonus, as it deems appropriate, in
               its discretion, to the Employee based upon such review. Such
               review and bonus shall be consistent with any bonus plan adopted
               by the Compensation Committee, which covers the executive
               officers and employees of the Company generally.

          C.   BENEFITS. During the Term of this Employment Agreement, the
               Employee will receive such employee benefits as are generally
               available to all employees of the Company.

          D.   STOCK OPTIONS. The Compensation Committee of the Board of
               Directors may, from time-to-time, grant stock options, restricted
               stock purchase opportunities and such other forms of stock-based
               incentive compensation as it deems appropriate, in its
               discretion, to the Employee under the Company's Stock Option and
               Restricted Stock Purchase Plan and the 1996 Stock Incentive Plan
               (the "Stock Plans"). The terms of the relevant award agreements
               shall govern the rights of the Employee and the Company
               thereunder in the event of any conflict between such agreement
               and this Employment Agreement.

          E.   VACATION. The Employee shall be entitled to twenty (20) days of
               vacation during each calendar year during the Term of this
               Employment Agreement.

          F.   EXPENSES. The Company shall reimburse the Employee for all
               reasonable out-of-pocket expenses incurred by him in the
               performance of his duties hereunder, including expenses for
               travel, entertainment and similar items, promptly after the
               presentation by the Employee, from time-to-time, of an itemized
               account of such expenses.

     4.   TERMINATION.

          A.   FOR CAUSE. The Company may terminate the employment of the
               Employee prior to the end of the Term of this Employment
               Agreement "for cause." Termination "for cause" shall be defined
               as a termination by the Company of the employment of the Employee
               occasioned by the failure by the Employee to cure a willful
               breach of a material duty imposed on the Employee under this
               Employment Agreement within 15 days after written notice thereof
               by the Company or the continuation by the Employee after written
               notice by the Company of a willful and continued neglect of a
               duty imposed on the Employee under this Employment Agreement. In
               the event of termination by the Company "for cause," all salary,
               benefits and other payments shall cease at the time of
               termination, and the Company shall have no further obligations to
               the Employee.

          B.   RESIGNATION. If the Employee resigns for any reason, all salary,
               benefits and other payments (except as otherwise provided in
               paragraph G of this Section 4 below) shall cease at the time such
               resignation becomes effective. At the time of any such
               resignation, the Company shall pay the Employee the value of any
               accrued but unused vacation time, and the amount of all

                                       -3-

<PAGE>

               accrued but previously unpaid base salary through the date of
               such termination, excluding any salary deferred under paragraph A
               of Section 3 above. The Company shall promptly reimburse the
               Employee for the amount of any expenses incurred prior to such
               termination by the Employee as required under paragraph G of
               Section 3 above.

          C.   DISABILITY, DEATH. The Company may terminate the employment of
               the Employee prior to the end of the Term of this Employment
               Agreement if the Employee has been unable to perform his duties
               hereunder for a continuous period of six (6) months due to a
               physical or mental condition that, in the opinion of a licensed
               physician, will be of indefinite duration or is without a
               reasonable probability of recovery. The Employee agrees to submit
               to an examination by a licensed physician of his choice in order
               to obtain such opinion, at the request of the Company, made after
               the Employee has been absent from his place of employment for at
               least six (6) months. The Company shall pay for any requested
               examination. However, this provision does not abrogate either the
               Company's or the Employee's rights and obligations pursuant to
               the Family and Medical Leave Act of 1993, and a termination of
               employment under this paragraph C shall not be deemed to be a
               termination for cause.

               If during the Term of this Employment Agreement, the Employee
               dies or his employment is terminated because of his disability,
               all salary, benefits and other payments shall cease at the time
               of death or disability, provided, however, that the Company shall
               provide such health, dental and similar insurance or benefits as
               were provided to Employee immediately before his termination by
               reason of death or disability, to Employee or his family for the
               longer of twelve (12) months after such termination or the full
               unexpired Term of this Employment Agreement on the same terms and
               conditions (including cost) as were applicable before such
               termination. In addition, for the first six (6) months of
               disability, the Company shall pay to the Employee the difference,
               if any, between any cash benefits received by the Employee from a
               Company-sponsored disability insurance policy and the Employee's
               salary hereunder in accordance with paragraph A of Section 3
               above. At the time of any such termination, the Company shall pay
               the Employee, the value of any accrued but unused vacation time,
               and the amount of all accrued but previously unpaid base salary
               through the date of such termination. The Company shall promptly
               reimburse the Employee for the amount of any expenses incurred
               prior to such termination by the Employee as required under
               paragraph G of Section 3 above.

          D.   TERMINATION WITHOUT CAUSE. A termination without cause is a
               termination of the employment of the Employee by the Company that
               is not "for cause" and not occasioned by the resignation, death
               or disability of the Employee. If the Company terminates the
               employment of the Employee without cause, (whether before the end
               of the Term of this Employment Agreement or, if the Employee is
               employed by the Company under paragraph E of this Section 4
               below, after the Term of this Employment Agreement has ended) the
               Company shall, at the time of such termination, pay to the
               Employee the severance payment provided in paragraph F of this
               Section 4 below together with the value of any accrued but unused
               vacation time and the amount of all accrued but previously unpaid
               base salary through the date of such termination and shall
               provide him with all of his benefits under paragraph C of Section
               3 above for the longer of twelve (12) months or the full
               unexpired Term of this Employment Agreement. The Company shall
               promptly reimburse the Employee for the amount of any expenses
               incurred prior to such termination by the Employee as required
               under paragraph F of Section 3 above.

               If the Company terminates the employment of the Employee because
               it has ceased to do business or substantially completed the
               liquidation of its assets or because it has relocated to another
               city and the Employee has decided not to relocate also, such
               termination of employment shall be deemed to be without cause.

          E.   END OF THE TERM OF THIS EMPLOYMENT AGREEMENT. Except as otherwise
               provided in paragraphs F and G of this Section 4 below, the
               Company may terminate the employment of

                                       -4-

<PAGE>

               the Employee at the end of the Term of this Employment Agreement
               without any liability on the part of the Company to the Employee
               but, if the Employee continues to be an employee of the Company
               after the Term of this Employment Agreement ends, his employment
               shall be governed by the terms and conditions of this Agreement,
               but he shall be an employee at will and his employment may be
               terminated at any time by either the Company or the Employee
               without notice and for any reason not prohibited by law or no
               reason at all. If the Company terminates the employment of the
               Employee at the end of the Term of this Employment Agreement, the
               Company shall, at the time of such termination, pay to the
               Employee the severance payment provided in paragraph F of this
               Section 4 below together with the value of any accrued but unused
               vacation time and the amount of all accrued but previously unpaid
               base salary through the date of such termination. The Company
               shall promptly reimburse the Employee for the amount of any
               reasonable expenses incurred prior to such termination by the
               Employee as required under paragraph F of Section 3 above.

          F.   SEVERANCE. If the employment of the Employee is terminated by the
               Company, at the end of the Term of this Employment Agreement or,
               without cause (whether before the end of the Term of this
               Employment Agreement or, if the Employee is employed by the
               Company under paragraph E of this Section 4 above, after the Term
               of this Employment Agreement has ended), the Employee shall be
               paid, as a severance payment at the time of such termination, the
               amount of One Hundred Thirty-Five Thousand Dollars ($135,000)
               together with the value of any accrued but unused vacation time.

          G.   CHANGE OF CONTROL SEVERANCE. In addition to the rights of the
               Employee under the Company's employee benefit plans (paragraphs C
               of Section 3 above) but in lieu of any severance payment under
               paragraph F of this Section 4 above, if there is a Change in
               Control of the Company (as defined below) and the employment of
               the Employee is concurrently or subsequently terminated (a) by
               the Company without cause, (b) by the expiration of the Term of
               this Employment Agreement, or (c) by the resignation of the
               Employee because he has reasonably determined in good faith that
               his titles, authorities, responsibilities, salary, bonus
               opportunities or benefits have been materially diminished, that a
               material adverse change in his working conditions has occurred,
               that his services are no longer required in light of the
               Company's business plan, or the Company has breached this
               Employment Agreement, the Company shall pay the Employee, as a
               severance payment, at the time of such termination, the amount of
               Two Hundred Seventy Thousand Dollars ($270,000) together with the
               value of any accrued but unused vacation time, and the amount of
               all accrued but previously unpaid base salary through the date of
               termination and shall provide him with all of this benefits under
               paragraph C of Section 3 above for the longer of twelve (12)
               months or the full unexpired Term of this Employment Agreement.
               The Company shall promptly reimburse the Employee for the amount
               of any expenses incurred prior to such termination by the
               Employee as required under paragraph F of Section 3 above.

               For the purpose of this Employment Agreement, a Change in Control
               of the Company has occurred when: (a) any person (defined for the
               purposes of this paragraph G to mean any person within the
               meaning of Section 13 (d) of the Securities Exchange Act of 1934
               (the "Exchange Act")), other than Neoprobe or an employee benefit
               plan created by its Board of Directors for the benefit of its
               employees, either directly or indirectly, acquires beneficial
               ownership (determined under Rule 13d-3 of the Regulations
               promulgated by the Securities and Exchange Commission under
               Section 13(d) of the Exchange Act) of securities issued by
               Neoprobe having thirty percent (30%) or more of the voting power
               of all the voting securities issued by Neoprobe in the election
               of Directors at the next meeting of the holders of voting
               securities to be held for such purpose; (b) a majority of the
               Directors elected at any meeting of the holders of voting
               securities of Neoprobe are persons who were not nominated for
               such election by the Board of Directors or a duly constituted
               committee of the Board of Directors having authority in such
               matters; (c) the stockholders of Neoprobe approve a merger or
               consolidation of Neoprobe with another person other than a merger
               or consolidation in which the holders of Neoprobe's voting
               securities issued and outstanding immediately before such

                                       -5-

<PAGE>

               merger or consolidation continue to hold voting securities in the
               surviving or resulting corporation (in the same relative
               proportions to each other as existed before such event)
               comprising eighty percent (80%) or more of the voting power for
               all purposes of the surviving or resulting corporation; or (d)
               the stockholders of Neoprobe approve a transfer of substantially
               all of the assets of Neoprobe to another person other than a
               transfer to a transferee, eighty percent (80%) or more of the
               voting power of which is owned or controlled by Neoprobe or by
               the holders of Neoprobe's voting securities issued and
               outstanding immediately before such transfer in the same relative
               proportions to each other as existed before such event. The
               parties hereto agree that for the purpose of determining the time
               when a Change of Control has occurred that if any transaction
               results from a definite proposal that was made before the end of
               the Term of this Employment Agreement but which continued until
               after the end of the Term of this Employment Agreement and such
               transaction is consummated after the end of the Term of this
               Employment Agreement, such transaction shall be deemed to have
               occurred when the definite proposal was made for the purposes of
               the first sentence of this paragraph G of this Section 4.

          H.   BENEFIT AND STOCK PLANS. In the event that a benefit plan or
               Stock Plan which covers the Employee has specific provisions
               concerning termination of employment, or the death or disability
               of an employee (e.g., life insurance or disability insurance),
               then such benefit plan or Stock Plan shall control the
               disposition of the benefits or stock options.

     5.   PROPRIETARY INFORMATION AGREEMENT. Employee has executed a Proprietary
          Information Agreement as a condition of employment with the Company.
          The Proprietary Information Agreement shall not be limited by this
          Employment Agreement in any manner, and the Employee shall act in
          accordance with the provisions of the Proprietary Information
          Agreement at all times during the Term of this Employment Agreement.

     6.   NON-COMPETITION. Employee agrees that for so long as he is employed by
          the Company under this Employment Agreement and for one (1) year
          thereafter, the Employee will not:

          A.   enter into the employ of or render any services to any person,
               firm, or corporation, which is engaged, in any part, in a
               Competitive Business (as defined below);

          B.   engage in any directly Competitive Business for his own account;

          C.   become associated with or interested in through retention or by
               employment any Competitive Business as an individual, partner,
               shareholder, creditor, director, officer, principal, agent,
               employee, trustee, consultant, advisor, or in any other
               relationship or capacity; or

          D.   solicit, interfere with, or endeavor to entice away from the
               Company, any of its customers, strategic partners, or sources of
               supply.

          Nothing in this Employment Agreement shall preclude Employee from
          taking employment in the banking or related financial services
          industries nor from investing his personal assets in the securities or
          any Competitive Business if such securities are traded on a national
          stock exchange or in the over-the-counter market and if such
          investment does not result in his beneficially owning, at any time,
          more than one percent (1%) of the publicly-traded equity securities of
          such Competitive Business. "Competitive Business" for purposes of this
          Employment Agreement shall mean any business or enterprise which:

          a.   is engaged in the development and/or commercialization of gamma
               radiation detection products and/or systems for use in
               intraoperative detection of cancer, or

          b.   reasonably understood to be competitive in the relevant market
               with products and/or systems described in clause a above, or

                                       -6-

<PAGE>

          c.   the Company engages in during the Term of this Employment
               Agreement pursuant to a determination of the Board of Directors
               and from which the Company derives a material amount of revenue
               or in which the Company has made a material capital investment.

          The covenant set forth in this Section 6 shall terminate immediately
          upon the substantial completion of the liquidation of assets of the
          Company or the termination of the employment of the Employee by the
          Company without cause or at the end of the Term of this Employment
          Agreement.

     7.   ARBITRATION. Any dispute or controversy arising under or in connection
          with this Employment Agreement shall be settled exclusively by
          arbitration in Columbus, Ohio, in accordance with the non-union
          employment arbitration rules of the American Arbitration Association
          ("AAA") then in effect. If specific non-union employment dispute rules
          are not in effect, then AAA commercial arbitration rules shall govern
          the dispute. If the amount claimed exceeds $100,000, the arbitration
          shall be before a panel of three arbitrators. Judgment may be entered
          on the arbitrator's award in any court having jurisdiction. The
          Company shall indemnify the Employee against and hold him harmless
          from any attorney's fees, court costs and other expenses incurred by
          the Employee in connection with the preparation, commencement,
          prosecution, defense, or enforcement of any arbitration, award,
          confirmation or judgment in order to assert or defend any right or
          obtain any payment under paragraph C of Section 4 above or under this
          sentence; without regard to the success of the Employee or his
          attorney in any such arbitration or proceeding.

     8.   GOVERNING LAW. The Employment Agreement shall be governed by and
          construed in accordance with the laws of the State of Ohio.

     9.   VALIDITY. The invalidity or unenforceability of any provision or
          provisions of this Employment Agreement shall not affect the validity
          or enforceability of any other provision of the Employment Agreement,
          which shall remain in full force and effect.

     10.  ENTIRE AGREEMENT.

          A.   The 2000, 2001 and 2003 Employment Agreements and the 2001
               Amendment are terminated as of the effective date of this
               Employment Agreement, except that awards under the Stock Plans
               granted to the Employee in the 2000, 2001 and 2003 Employment
               Agreements and the 2001 Amendment or in any previous employment
               agreement or by the Compensation Committee remain in full force
               and effect.

          B.   This Employment Agreement constitutes the entire understanding
               between the parties with respect to the subject matter hereof,
               superseding all negotiations, prior discussions, and preliminary
               agreements. This Employment Agreement may not be amended except
               in writing executed by the parties hereto.

     11.  EFFECT ON SUCCESSORS OF INTEREST. This Employment Agreement shall
          inure to the benefit of and be binding upon heirs, administrators,
          executors, successors and assigns of each of the parties hereto.
          Notwithstanding the above, the Employee recognizes and agrees that his
          obligation under this Employment Agreement may not be assigned without
          the consent of the Company.

IN WITNESS WHEREOF, the parties hereto have executed and delivered this
Employment Agreement as of the date first written above.

NEOPROBE CORPORATION                                  EMPLOYEE

By: /s/ David C. Bupp                                 /s/ Carl. M. Bosch
   ------------------------------------------         --------------------------
    David C. Bupp, President and CEO                  Carl M. Bosch

                                       -7-<PAGE>
                                                                   EXHIBIT 10.22

CONFIDENTIAL TREATMENT - Asterisked material has been omitted and filed
separately with the Securities and Exchange Commission pursuant to a request for
confidential treatment.

                            PRODUCT SUPPLY AGREEMENT

This Agreement dated February 5, 2004, by and between NEOPROBE CORPORATION, a
Delaware corporation, having an office at 425 Metro Place North, Suite 300,
Dublin, OH 43017 ("Company"), and TRIVIRIX INTERNATIONAL, a Delaware
corporation, having an office at 2800 Meridian Parkway, Suite 175, Durham, North
Carolina 27713 ("TriVirix");

                              W I T N E S S E T H:

            WHEREAS, Company wishes to have TriVirix manufacture for it the
Product(s) (as hereinafter defined);

            WHEREAS, Company wishes to have TriVirix service and repair the
Product(s) and certain predecessor products;

            WHEREAS, TriVirix is engaged in the business of manufacturing,
servicing and repairing electronic equipment; and

            WHEREAS, TriVirix desires to so manufacture and supply and service
and repair the Product(s) for Company:

            NOW, THEREFORE, the parties agree as follows:

                                   ARTICLE I

                                   DEFINITIONS

            1.01 "Affiliate(s)" shall mean with respect to a party any other
corporation controlling, controlled by or under common control with such party
during the term or any extension of this Agreement.

            1.02 "Commercial Years" shall be defined as follows: "Commercial
Year One" or the "First Commercial Year" shall mean the period from the Date of
Market Introduction as defined in Section 1.04 through December 31, 2004;
provided, however, that the Date of Market Introduction shall be no later than
February 1, 2004. In the event that the Date of Market Introduction is after
February 1, 2004, the Parties shall negotiate in good faith any adjustment
necessary to the minimum purchase commitment created under the blanket Purchase
Orders delivered in accordance with Section 3 and the price of such Products as
determined in Section 3.

            1.03 "Confidential Information" shall mean all information, data and
know-how that concerns the business affairs of a party that is not known by or
generally available to third parties, and which is disclosed by a party to the
other party. Confidential Information may be in tangible or intangible form,
including, without limitation, oral or written disclosures,
<PAGE>
ideas, know-how, drawings, graphs, plans, specifications, models, prototypes,
samples, equipment, data, formulas, processes, designs, hardware and software,
and information about marketing, costs and suppliers. All written Confidential
Information shall be prominently identified as such using appropriate legends,
markings, stamps, or other clear and conspicuous written identification that
unambiguously indicates that the information being provided is to be considered
Confidential Information hereunder. A disclosing party shall identify as
Confidential Information only such information as the disclosing party believes
in good faith to be proprietary or competition sensitive. Any information that
is disclosed other than in tangible or other written form shall be considered
Confidential Information but only to the extent that it is identified as
Confidential Information at the time of disclosure and is thereafter summarized
in written form which clearly and conspicuously identifies it as Confidential
Information. The term Confidential Information shall not mean any information
which is previously known to the receiving party without obligation of
confidence, as shown by its written records, or without breach of this
Agreement, is publicly disclosed either prior or subsequent to receipt by the
receiving party of such Confidential Information, or is subsequently rightfully
received by the receiving party from a third party without obligation of
confidence or disclosure of which is required by subpoena or other legal,
administrative, or arbitral process or by law. The fact that a party chooses to
transmit Confidential Information to the other party hereto via E-mail shall not
in any way release said information from its status as Confidential Information
hereunder.

            1.04 "Date of Market Introduction" of a Product shall mean the date
of the receipt and acceptance by Company of the first twenty (20) units of the
Product meeting the specifications of the DMR for said Product.

            1.05 "Defective Product" shall mean a Product manufactured by
TriVirix hereunder that does not function or fails to meet the specifications of
the DMR, or has defects in materials or workmanship.

            1.06 "DMR" shall mean the Device Master Record for a Product, which
shall be maintained in compliance with the QSR. The DMR shall include the
specifications, drawings, and manufacturing instructions that enable TriVirix or
a third party to manufacture the Products including a set of quality control
parameters suitable for use in acceptance testing of the Products, but excluding
applicable software.

            1.07 "DHR" shall mean the Device History Record for a Product, which
shall be maintained in compliance with the QSR. The DHR shall include a
compilation of records used in the production, inspection, test, and warehousing
or shipping activities related to the Products (i.e., certificates of
conformance, evidence of appropriate labeling.

            1.08 "Engineering Change Notice" or "ECN" shall mean the controlled
change process to effect changes to the Products, processes, or documentation.

            1.09 "FDA" shall mean the United States Food and Drug
Administration.

            1.10 "Forecast" shall have the meaning set forth in Section 2.04
herein.

            1.11 "Forecast Period" shall have the meaning set forth in Section
2.04 herein.

                                       2
<PAGE>
            1.12 "Initial Term" shall have the meaning set forth in Section 8.01
hereof.

            1.13 "NCNR components" shall mean those parts of the Products orders
for which once placed with TriVirix's suppliers are not cancelable, or that are
not returnable once delivered to TriVirix without payment of a restocking or
other fee that Company agrees to pay.

            1.14 "Product(s)" shall mean the medical device(s) listed in
Schedule 1.12 to this Agreement, as such Schedule may be amended from time to
time through written agreement between the parties, that is the subject of a
DMR(s).

            1.15 "Purchase Orders" shall have the meaning set forth in Section
2.04(b) hereof.

            1.16 "QSR" shall mean the Quality System Regulation (21 CFR 820)
promulgated by the FDA, as may be amended from time to time during the term of
this Agreement.

            1.17 "Sustaining Engineering" shall mean the design/drafting
services to maintain DMR and associated drawings; the design, analysis and
verification testing of design improvements; the support of process validations
and quality issues of in-house and sub-tier suppliers; or other engineering
services agreed-to in writing by both parties.

                                   ARTICLE II

                       SUPPLY, SUPPORT AND REPAIR SERVICES

            2.01 TriVirix shall manufacture and sell the Products exclusively to
Company at prices established by the parties pursuant to paragraph 3.01 for
Company's exclusive resale or use.

            2.02 During the term of this Agreement, TriVirix shall be Company's
sole and exclusive source for the Products, provided that (a) TriVirix provides
an adequate and timely supply of the Products to Company in accordance with
paragraph 2.04 hereof, and (b) TriVirix maintains compliance with the QSR and
the quality assurance level agreed upon by the parties.

            2.03 TriVirix represents that it will from and after December 1,
2003, maintain sufficient manufacturing capacity, including printed circuit
board production, to produce the number of Products forecast by Company in its
Forecasts submitted pursuant to paragraph 2.04 hereof. With respect to printed
circuit boards to be built at TriVirix' facility in Northern Ireland, TriVirix
shall take reasonable measures to establish a contingent source of supply
capable of delivering finished boards within 60 days of an interruption of
supply in TriVirix' Northern Ireland facility that lasts longer than 10 days.

            2.04 (a) In order to facilitate TriVirix's planning of production,
Company shall submit not later than the 15th day of each month to TriVirix an
estimate of its requirements for Products (the "Forecast") covering a forward
period of not less than twelve (12) months (the

                                       3
<PAGE>
"Forecast Period"). The first three (3) months shall be binding on Company on a
rolling basis advancing month-by-month and may not be canceled or rescheduled
without the prior written agreement of TriVirix. The remaining nine (9) months
forecast is to be used by TriVirix for planning purposes only and shall not be
considered to be firm as it relates to scheduling, Company's only obligation
with respect thereto being for the cost of any unique NCNR components having a
lead time of more than three (3) months on a rolling basis advancing month by
month. Company shall submit the initial Forecast promptly after the execution
and delivery of this Agreement.

            (b) Company shall commit to minimum annual purchase quantities for
each Product no less than ninety (90) days prior to the beginning of each
Commercial Year. As evidence of the Company's minimum annual commitments, the
Company will place an annual blanket purchase order for the following year's
minimum purchase requirement. TriVirix shall evidence its receipt of each
Purchase Order by signing an acknowledgment copy thereof and returning it to
Company within fifteen (15) days after receipt of such Purchase Order from
Company. The first Purchase Order delivered for each Commercial Year shall
constitute the Initial Forecast for said Commercial Year. In case of conflict
between the general terms and conditions of a Purchase Order issued by Company
and this Agreement, the terms and conditions of this Agreement shall take
precedence.

            2.05 TriVirix agrees to warehouse and store on Company's behalf all
finished Products in accordance with the terms outlined in Schedule 2.05(a).
TriVirix shall be entitled to invoice the Company for Product(s) on the date
TriVirix receives written acceptance from the Company of the Certificate of
Conformance ("CofC") for the completed Products and puts the Products into
storage on the Company's behalf; however, in the event written acceptance from
the Company is not received within two (2) working days and the Company has not
rejected the CofC related to such Products in good faith, TriVirix shall be
entitled to invoice the Company for such product on the third working day
following submittal of the Certificate of Conformance to the Company. Products
stored by TriVirix shall be ready to ship, F.O.B. TriVirix's facility, per the
Company's written instruction, to the Company or its subcontract distributors
listed in Schedule 2.05(b).

            2.06 If Company desires to accelerate or reduce any of the
deliveries ordered under a Purchase Order or set forth in a binding Forecast, it
shall so notify TriVirix and TriVirix shall make reasonable efforts to meet the
request, subject to material and capacity availability. Company shall bear and
pay any reasonable extra costs incurred by TriVirix to meet an accelerated or a
reduced schedule, including, without limitation, the cost to TriVirix of holding
inventory. During the Term of this Agreement, Company shall purchase and take
delivery of the quantities of Products listed in as delineated in the annual
blanket Purchase Orders per Section 2.04(b). In the event that Company delivers
a Forecast to TriVirix which indicates the Company does not intend to take
delivery of at least seventy-five percent (75%) of the minimum requirements
established by the Initial Forecast for any one (1) Commercial Year period, the
Company shall work in good faith with TriVirix to adjust the purchase price (if
appropriate) on all units of the relevant Product(s)to be purchased by Company
over the remaining portion of said Commercial Year and a maximum period of
ninety days during the following Commercial Year to reflect the reduced quantity
as far as overhead absorption, material costs and labor efficiency are
concerned. In the event the Company does not place an

                                       4
<PAGE>
order for the following Commercial Year, then the funds due shall be paid within
sixty (60) days of the end of the Commercial Year for which the Forecast was
decreased by more than 25% from the Initial Forecast. In the event the demand
exceeds the blanket order quantity, 1) the blanket order shall be adjusted
immediately to reflect the projected needs, and 2) the price which may be
subject to downward adjustment shall be addressed in accordance with Section
3.02.

            2.07 Company agrees to reimburse TriVirix for the cost of any and
all NCNR components ordered within the Forecast to meet demand within individual
Product lead times that become obsolete due to changes in the design requested
by Company. TriVirix agrees to make all reasonable effort(s) to return or sell
obsolete material.

            2.08 All Products shall be sold and delivered per paragraphs 2.05
and 4.03. All invoices shall be due and payable net thirty (30) days from the
date of the invoice.

            2.09 Any Company owned equipment (test equipment, tooling, test
fixtures, etc) supplied to TriVirix shall be utilized for its intended purpose
only. TriVirix shall properly identify Company owned equipment as such. TriVirix
shall not be liable for the maintenance of the equipment nor for normal wear and
tear. TriVirix shall be liable for any abuse, mistreatment and negligence of
said equipment.

            2.10 All end item deliverable devices shall have validated tests to
ensure reliable results. All Company provided test equipment and test procedures
shall have proof of validation. Copies of the validations shall be provided to
TriVirix.

            2.11 TriVirix shall obtain the written approval of Company prior to
making any changes, substitutions, or modifications to the Product(s) or the DMR
in accordance with the Change Notification Protocol, a copy of which has been
provided to Company. Company shall promptly respond to any such request for
approval of changes. It is recognized that TriVirix may, from time to time, be
asked to implement ECNs. The following delineates the proper procedure:

                  (a) Company will notify TriVirix in writing of the proposed
change. This notification should include the documentation of the change to
effectively support TriVirix's investigation of the impact of this proposal;

                  (b) Upon receipt of a notice requesting a change, TriVirix
will review and respond to all cost impacts within a reasonable period of time
not to exceed thirty (30) days;

                  (c) All cost impacts and material availability issues will be
mutually reviewed and agreed to in writing prior to implementation; and

                  (d) Emergency ECNs as identified by Company in writing will be
immediately implemented at Company's request. Company will be liable for all
reasonable costs associated with the implementation of emergency ECNs, except,
if the emergency ECN (i) is the result of a defect in the design of the
Product(s) provided by TriVirix, (ii) is the direct result of a defect in a part
or sub-component from a supplier to TriVirix, or (iii) is the direct result of a
defect in workmanship by TriVirix. TriVirix shall provide for the repair and /or
replacement of defective Products identified in (i), (ii) and (iii) at its cost.

                  (e) Component Substitutions. TriVirix reserves the right to
substitute passive electronic components without prior Company approval
provided, however, that the

                                       5
<PAGE>
components are of equal or more stringent specification than the originally
indicated part, the components conform to all applicable specifications and do
not increase the risks of stoppage of manufacturing, safety, quality,
durability, or reliability and that adequate record is maintained of the
substitution within the DMR as well as the applicable Product DHR and
notification is provided to the Company on a timely basis. Component selection
that may affect the aforementioned risk categories related to the manufacture of
a Product should immediately be communicated to the Company's RA/QA Department.

                  (f) Supplier Selection. In the absence of design-specified
sources of supply, TriVirix reserves the right of complete control in the choice
of component suppliers without Company approval. Source selection and
qualification shall be in accordance with TriVirix' Quality System requirements.

            2.12 The Products shall be packaged and labeled in accordance with
Company's specifications. Company shall prepare the artwork necessary for
printing all labels and shall deliver it to TriVirix as least ten (10) weeks
prior to the scheduled delivery from TriVirix of the first shipment of Products
ordered by Company.

            2.13 From and after sixty (60) days from the date of this Agreement,
TriVirix shall provide to Company a list or recommended repair service parts or
spare parts for Products and certain predecessor products, on terms and
conditions to be agreed upon in a separate agreement. The service agreement
shall be concluded within thirty (30) days of this Agreement. Service may extend
to other Company products as well, and shall not be limited to the Products.

            2.14 From and after sixty (60) days from the date of this Agreement,
TriVirix shall provide to Company Sustaining Engineering services for Products,
on terms and conditions to be agreed upon in a separate agreement. The
Sustaining Engineering agreement shall be concluded within thirty (90) days of
this Agreement.

            2.15 TriVirix warrants, covenants and agrees that (a) it will
maintain an FDA registered facility certified to ISO 13488, and (b) the Products
will be manufactured and supplied by TriVirix to Company in compliance with all
applicable laws, ordinances, rules and regulations, whether local, state or
federal, including, but not limited to, the provisions of the federal Food, Drug
and Cosmetic Act, and QSR. TriVirix will provide documentation that the TriVirix
facility complies with FDA published guidelines (as defined in 21 CFR 10.90b)
and upon request by Company shall demonstrate such compliance. Company shall
have the right upon at least five (5) business days prior notice in writing to
inspect during normal business hours TriVirix's quality control system,
documentation, receiving, shipping, warehousing, and manufacturing processes and
facilities for the Product(s). The Parties agree that all work required by this
Agreement to be performed by TriVirix shall be performed solely by TriVirix or
its qualified subcontractors. TriVirix agrees to manufacture, assemble, and
package the Products or perform services in accordance with this Agreement.
Company may review TriVirix' performance of the work under this Agreement,
including development, fabrication and test of the Products, the design of the
tools used to produce them, and their operation. To review the work, Company may
visit the sites where TriVirix or TriVirix' subcontractor performs it. TriVirix
shall make available by electronic or other means any information required by
Company to be obtained or maintained as it relates to Products, including
current data regarding status and performance on Purchase Orders.

                                       6
<PAGE>
                                  ARTICLE III

                      PRICE FOR PRODUCTS; TERMS OF PAYMENT

            3.01 TriVirix agrees to sell and deliver to Company in accordance
with paragraph 2.04, and Company agrees to purchase Products from TriVirix, at
the prices listed in Schedule 3.01.

            3.02 The price for each Product shall be fixed for the First
Commercial Year; provided, however, in the event of a material increase in the
cost of any material component or the sum of materials used in the manufacture
of a Product that affects the material cost by greater than ten percent (10%),
TriVirix shall have the right to renegotiate the prices then in effect.
Conversely, if TriVirix or the Company becomes aware of a material decrease in
the cost of any material component or the sum of materials used in the
manufacture of a Product that would decrease the material cost of the Product by
greater than * * *, the Company shall have the right to renegotiate the price
then in effect. Any price adjustments as a result of the above scenario shall
apply to the products yet to be delivered. Not later than September 30, 2004 and
annually thereafter the parties shall meet and negotiate in good faith the
prices for the Products for the ensuing Commercial Year using the pricing
formula comprised of fixed overhead rates and profit percentages outlined on
Schedule 3.01.

            3.03 The prices listed in Schedule 3.01 shall include manufacturing
engineering support (not including reengineering of the manufacturing process)
provided on an "as needed" basis to support ECNs and Non-conforming Material
Reports (NMRs) along with Statistical Process Control . Manufacturing and
quality engineers, as appropriate, will perform these activities. All customer
ECNs are subject to cost and schedule adjustment.

            3.04 (a) TriVirix shall perform transfer engineering services
required in connection with the transfer of the manufacturing process for the
Products from Company's current supplier to TriVirix, initial qualification of
sub-tier suppliers and setting up the production line for the fees listed in
TriVirix proposals 03-2003-17 Rev. A, dated 10 June 2003 and 04-2003-18 Rev. A,
dated 11 June 2003.

      (b) When TriVirix validates the manufacturing lines, it shall track first
pass yields to understand better the capabilities of Company's designs,
suppliers and manufacturing processes. TriVirix and Company shall then evaluate
the need for any non-recurring efforts to resolve mutually agreed quality or
yield issues and TriVirix shall supply those services to Company on a time and
materials basis based on (a) actual hours worked at TriVirix's then current
billing rate, and (b) direct expenses incurred and paid to third parties, plus
material overhead only. Travel expenses for such incremental efforts will be
billed at cost plus 5%. Travel expenses shall include mileage at the latest rate
determined by the Internal Revenue Service, parking tolls and fares, car rental
fees, if required, air fare, if required, and food and lodging away from the
home office. Travel time will be billed at the individual's then current billing
rate. TriVirix shall invoice Company no more frequently than bi-weekly for its
charges associated with such

                                       7
<PAGE>
incremental non-recurring efforts, with payment due from Company within thirty
(30) days from the date of TriVirix's invoice.

            3.05 A late fee of * * * per month may be assessed by TriVirix on
invoices not paid by Company within the later of thirty (30) days of the date of
receipt of the original invoice or ten (10) business days from the Company's
receipt of any corrected invoice other than on the amount of said invoices being
contested in good faith. Payment shall be by wire to (all wire fees payable by
TriVirix):

            * * *

                        2800 Meridian Parkway, Ste 175

                        Durham, NC 27713

            3.06 Company is hereby extended an initial credit limit of $200,000.
The parties agree to review the credit limit no less than semi-annually from the
effective date of this Agreement and revise the credit limit, if necessary, to a
mutually agreed amount to reflect the Company's forecasted purchases and payment
history. Should the credit limit be at risk or should the Company have balances
past due by more than ten (10) days which are not disputed in good faith,
TriVirix reserves the right to request immediate payment to bring the Company's
account back to good standing prior to further shipments taking place.

            3.07 * * *

            3.08 * * *

                                   ARTICLE IV

                         INSPECTION AND QUALITY CONTROL

            4.01 TriVirix shall, at its discretion, either accept or create an
internal Quality Assurance Plan(s) that is compliant with the Quality Assurance
Plan(s) provided by the Company. The Quality Assurance Plan(s) shall be approved
by the Company.

            4.02 Prior to the Date of Market Introduction, TriVirix shall
perform at Company's expense (as included in the transfer engineering fees
provided for in paragraph 3.04) a Process Failure Modes and Effects Analysis
(PFMEA) to verify robustness of the manufacturing process. Process Validation
testing shall be performed at Company's expense (as included in the transfer
engineering fees provided for in Paragraph 3.04 above) prior to the start of
production to ensure that the equipment and processes operate as designed.
Annual Process Qualifications shall be performed by TriVirix to verify the
stability of the production process and to look for improvements in the
calibration and test process.

                                       8
<PAGE>
            4.03 TriVirix shall establish and maintain quality records for each
unit of Product(s) produced (identified by serial number) consisting of, at a
minimum, but not limited to:

            (a) Certificate of Conformance;

            (b) Label Certification Sheet; and,

            (c) Device History Record.

            4.04 TriVirix shall present these quality records to Company for
immediate inspection by Company on completion of the production cycle, and prior
to release of Product into storage per paragraph 2.05. Upon receipt of said
records, Company shall perform an immediate inspection of these quality records,
and shall within two (2) business days, provide written inspection status
(Pass/Reject) to by fax TriVirix. TriVirix shall maintain these quality records
for a period of seven (7) years after the last date of manufacture for a
Product, or as prescribed by applicable medical device regulations, whichever is
longer unless otherwise agreed to in writing by both Parties. Within fifteen
(15) days after delivery of Products into storage per paragraph 2.05, Company
shall have the right to conduct its product audit to include a physical
inspection of Products delivered thereof in which Products will be compared with
the specifications and quality control parameters contained in the Quality
Assurance Plan and DMR, and shall inform TriVirix of the results of such
inspection. In the event such inspection by Company reveals unacceptable
variances from the specifications and quality control parameters contained in
the Quality Assurance Plan and DMR, Company shall notify TriVirix (which notice
shall specify the manner in which the defective Products fail to meet the
specifications in the DMR), and TriVirix shall have fifteen (15) days in which
to verify the variances. Upon the earlier of (a) verification by TriVirix or (b)
the expiration of thirty (30) days from the date of said notice, Company shall
have the right to refuse acceptance of the defective or deficient shipment(s)
and to require, at the option of TriVirix, that said Products be replaced or
corrected free of charge to the Company. If TriVirix's inspection results in a
finding that the Products are not defective or deficient, TriVirix shall
immediately notify Company of the same and shall resubmit the Products for
acceptance. In the event that TriVirix and Company do not agree on the
acceptability of a Product, both parties agree to conduct joint testing and/or
inspection. Failure of Company to complete the above-mentioned acceptance
inspection within said fifteen (15) day period shall constitute acceptance by
Company of the Products, however such acceptance shall not reduce the Warranty
coverage for Products provided in accordance with Article VII herein.

                                   ARTICLE V
                            CONFIDENTIAL INFORMATION

            5.01 During the term of this Agreement and for a period of three (3)
years after its termination, TriVirix and Company each agree to hold all
Confidential Information of the other party disclosed to it hereunder in
confidence and not to disclose such Confidential Information of the other party
to any third party, except those who have a need to know such

                                       9
<PAGE>
Confidential Information for purposes of carrying out the terms of this
Agreement and are bound by a similar obligation of confidentiality and non-use,
and not to use such Confidential Information for any purpose other than for the
purposes of this Agreement. Thereafter, the right of one party to use the
Confidential Information of the other shall be limited only by the copyright and
patent rights of the other party.

            5.02 Each party represents to the other that its employees are
governed by company regulations that prohibit the disclosure of confidential and
proprietary information that may belong to the other party and that such
internal regulations will enable it to comply with all of the items of this
Agreement.

            5.03 TriVirix acknowledges that Company possesses certain
inventions, processes, know-how, trade secrets, improvements, other intellectual
properties and other assets, including but not limited to procedures and
techniques, computer technical expertise, software, and certain technical
expertise and conceptual expertise in their field of interest, which have been
independently developed by Company or its affiliates without the benefit of any
information provided by TriVirix (collectively "Company Property"). TriVirix and
Company agree that any Company Property or improvements thereto which are used,
improved, modified or developed by Company under or during the term of this
Agreement are the product of Company's technical expertise possessed and
developed by Company or its affiliates prior to or during the performance of
this Agreement are the sole and exclusive property of Company or its affiliates,
as the case may be.

            5.04 Company acknowledges that TriVirix possesses certain
inventions, processes, know-how, trade-secrets, improvements, cost and pricing
rates and data, other intellectual properties and other assets, including but
not limited to procedures and techniques, computer technical expertise,
software, and certain technical expertise and conceptual expertise in the area
of medical device design, manufacturing, and servicing, which have been
independently developed by TriVirix or its affiliates without the benefit of any
information provided by Company (collectively "TriVirix Property"). Company and
TriVirix agree that any TriVirix Property or improvements thereto which are
used, improved, modified, or developed by TriVirix under or during the term of
this Agreement are the product of TriVirix' technical expertise possessed and
developed by TriVirix or its affiliates prior to or during the performance of
this Agreement and are the sole and exclusive property of TriVirix or its
affiliates, as the case may be.

            5.05 If efforts under this Agreement result in inventions which are
jointly developed by TriVirix and Company because employees or agents of each of
TriVirix and Company make inventive contributions thereto, those employees or
agents of both parties would be or are properly named as co-inventors under the
laws of Delaware on any patent application claiming such inventions. In such
instance of a jointly developed invention Company shall have full rights to
exploit such jointly developed invention for its own commercial purposes without
any obligation to TriVirix. Any decision to file for patent coverage on jointly
developed inventions shall be mutually agreed on, and the parties will select a
mutually acceptable patent counsel to file and prosecute patent applications
based on such joint inventions.

                                       10
<PAGE>
            5.06 TriVirix agrees to return to Company all copies of
specifications and related materials within thirty (30) business days of such
termination.

            5.07 Notwithstanding any other provision of this Article, all
designs and specification for any Product or component thereof, and all related
writings, drawings, artwork, computer assisted designs, blueprints, annuals,
notes, notebooks, reports, memoranda and similar works and material, regardless
of whether created by the Company, TriVirix, or jointly, and regardless of
whether included in the DMR for the Product, shall be Company Property, and the
Company shall be the exclusive owner thereof and shall retain all right, title
and interest, including copyright, relating to such material.

                                   ARTICLE VI

                             LICENSE FOR USE OF DMR

            6.01 Company hereby grants TriVirix a non-exclusive, non-assignable,
royalty free license to use the DMR to manufacture the Products during the term
of this Agreement, and for no other purpose.

            6.02 Company shall have full design and Quality System Regulation
(QSR) responsibility including adverse event reporting unless otherwise noted in
this Agreement.

            6.03 TriVirix hereby grants Company a royalty free license for the
use of any manufacturing methods and processes developed by TriVirix for the
Products for use only in connection with the manufacture of any Products.

                                  ARTICLE VII

                         WARRANTIES AND INDEMNIFICATION

            7.01 TriVirix warrants to Company that all Products to be supplied
hereunder will upon shipment meet the specifications in the DMR and will be free
from defects in materials and workmanship. TRIVIRIX MAKES NO OTHER WARRANTIES,
WRITTEN, ORAL, OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY IMPLIED WARRANTIES
OF DESIGN, MERCHANTABILITY OR FITNESS FOR ANY SPECIFIC OR GENERAL PURPOSE. This
limited warranty shall apply for a period of twelve (12) months after the date
of shipment by TriVirix of the Product from storage at TriVirix's facilities to
the Company or its subcontract distributors per Section 2.05, but in no event
longer than fifteen (15) months from the date of acceptance by the Company of
the Certificate of Conformance for the Product pursuant to Section 4.3. TriVirix
shall satisfy this warranty requirement by repairing or replacing, at TriVirix's
option, each Defective Product returned to it prior to the expiration of the
warranty period. Satisfaction of TriVirix's warranty shall include the cost of
shipping repaired or replaced product, as appropriate. To the maximum extent
practical, TriVirix shall promptly document and return any defective material
under warranty from sub-tier suppliers so that these

                                       11
<PAGE>
items can be repaired or replaced and used in the respective production and/or
service units. Company, its distributors, customers, or other designee may
return Products to TriVirix that are determined by Company to be defective or
that need repair. Upon determination of any defective Product, Company may
request, and TriVirix shall issue, a "return authorization number" enabling
Company or the end-user to ship such Product on a freight-collect basis to
TriVirix. TriVirix shall, at TriVirix' option, either replace or repair Products
found to be defective during the Warranty period with Products which conform to
the Product Specifications which are part of this Agreement and in force at the
time the defective Products were originally delivered. Products returned for
defects in workmanship and/or materials during the Warranty Period will be
repaired and shipped back to the appropriate destination at no charge to
Company. Repair of non-warranty and/or post-warranty Products shall be in
accordance with Company's instruction. Repair and shipping costs for Products
returned for defects that are not the responsibility of TriVirix, including
Products that have been improperly used and/or handled, non-warranty Products,
and post-warranty Products, shall be paid by Company. If the Products are
returned to TriVirix, and TriVirix determines that said Products are not
defective in any way, and Company agrees with TriVirix' findings, Company agrees
to pay TriVirix a fixed amount to be negotiated between TriVirix and Company (no
defects found charge) for each such Product. TriVirix' warranty shall not apply
to any defects caused by improper use, handling, or transportation, unless
improperly packaged by TriVirix for delivery to Company or its designee.
TriVirix shall not be responsible for any costs associated with a recall over
and above its Warranty obligations hereunder. Company shall notify TriVirix
within 2 working days of any field corrections or removal from market (i.e.,
recalls) of the product TriVirix is manufacturing or providing service for.
Company shall have insurance of appropriate value to cover potential recall of
Products manufactured under this agreement.

            7.02 TriVirix shall, conduct a failure analysis as required by US
Food and Drug Administration ("FDA") regulations, i.e. 21 CFR Parts 820.115 and
820.198(b) with respect to Defective Products returned to it under paragraph
7.01. Such analysis shall be conducted promptly upon receipt by TriVirix of the
subject Defective Product and a results report shall be returned to Company no
later than forty-five (45) days after TriVirix's receipt of the defective
Product. The cost of such failure analysis shall be borne by TriVirix if the
analysis confirms that the failure is related to an issue covered by TriVirix's
limited warranty set forth in Paragraph 7.01 above to the Company or by the
Company in the absence of such confirmation.

            (a) TriVirix shall indemnify, defend and save Company, its
shareholders, directors, officers, employees, representatives and agents
("Company Indemnified Parties") harmless against any and all claims, suits,
proceedings, recoveries, settlements and damages, including, but not limited to,
reasonable attorney and paralegal fees, interest and penalties ("Claims")
arising or resulting from (i) the death of, or bodily injury to, any person on
account of the use of any Product to the extent caused by TriVirix' failure to
deliver such Product in accordance with TriVirix' warranties as provided in this
Agreement, or (ii) the material breach by TriVirix of any of its obligations
under this Agreement.

            (b) Company shall be liable for and shall indemnify, defend and save
TriVirix, its shareholders, directors, officers, employees, representatives and
agents ("TriVirix Indemnified Parties") harmless from and against any and all
Claims, whether groundless or not, in connection with (i) any materials,
formulae, instructions, specifications, standards, programs

                                       12
<PAGE>
or policies furnished by Company to TriVirix, (ii) any and all injuries, losses,
damages, or liability of any kind whatsoever directly or indirectly attributable
to the design of the Products (except to the extent designed by TriVirix) or any
omission or misstatement in the literature supplied by Company for use with the
Products, (iii) the distribution, marketing or sale of the Products, (iv) the
alleged infringement of any patent (including utility models and registered
designs), copyrights or other intellectual property rights relating to the
design of the Products (except to the extent designed by TriVirix) and any
literature supplied by Company for use with the Products, and (e) the material
breach by Company of any of its obligations under this Agreement.

            (c) NOTWITHSTANDING ANYTHING TO THE CONTRARY IN THIS AGREEMENT
(EXCEPT FOR THE PARTIES' OBLIGATIONS TO INDEMNIFY AGAINST CLAIMS OF THIRD
PARTIES UNDER 7.02(a) and 7.02(b) ABOVE), (i) UNDER NO CIRCUMSTANCES WILL ANY
PARTY, ITS EMPLOYEES, OFFICERS OR DIRECTORS, AGENTS, SUCCESSORS OR ASSIGNS BE
LIABLE TO ANOTHER PARTY AND ITS EMPLOYEES, OFFICERS OR DIRECTORS, AGENTS,
SUCCESSORS OR ASSIGNS UNDER ANY CONTRACT, STRICT LIABILITY, TORT (INCLUDING
NEGLIGENCE) OR OTHER LEGAL OR EQUITABLE THEORY, FOR ANY SPECIAL, INCIDENTAL,
EXEMPLARY, INDIRECT OR CONSEQUENTIAL COSTS OR DAMAGES, INCLUDING WITHOUT
LIMITATION LOST PROFITS, LITIGATION COSTS, LOSS OF DATA, PRODUCTION OR PROFIT,
ARISING OUT OF OR RELATING IN ANY WAY TO THE SUBJECT MATTER OF THIS AGREEMENT,
AND (ii) UNDER NO CIRCUMSTANCES WILL ANY PARTY'S AGGREGATE LIABILITY UNDER THIS
AGREEMENT EXCEED $_500,000.

            (d) A Company Indemnified Party or a TriVirix Indemnified Party (the
"Indemnified Party") shall notify the other party (the "Indemnifying Party") in
writing of any action, claim or other matter in respect of which the Indemnified
Party or any of its affiliates, or any of their respective directors, officers,
employees or agents intend to claim such indemnification; provided, however, the
failure to provide such notice within a reasonable period of time shall not
relieve the Indemnifying Party of any of its obligations hereunder except to the
extent the Indemnifying Party is prejudiced by such failure. The Indemnified
Party, its affiliates, and their respective directors, officers, employees and
agents shall cooperate fully with the Indemnifying Party and its legal
representatives in the investigation, negotiation, compromise, settlement and
defense of any action, claim or other matter covered by this indemnification.
The Indemnifying Party shall be in charge of and control any such investigation,
negotiation, compromise, settlement and defense and shall have the right to
select counsel with respect thereto, provided that Indemnifying Party shall
promptly notify the Indemnified Party of all material developments in the
matter. In no event shall the Indemnifying Party compromise or settle any such
matter without the prior written consent of Indemnified Party, which shall not
be bound by any such compromise or settlement absent its prior consent, which
shall not be unreasonably withheld or delayed. The Indemnified Party shall have
the right, but not the obligation, to be represented by counsel of its own
selection and at its own expense.

            (e) The indemnity obligations set forth in this Agreement shall
survive the expiration or termination of this Agreement.

                                       13
<PAGE>
                                  ARTICLE VIII

                       TERM, TERMINATION AND CANCELLATION

            8.01 The term of this Agreement shall begin the date hereof and
unless terminated earlier in accordance with paragraph 8.02 shall continue for
three (3) years from the Date of Market Introduction (the "Initial Term").

            8.02 After the Initial Term, the term shall automatically be
extended for successive one (1) year periods, provided, however, that this
Agreement may be terminated by TriVirix or Company upon one hundred and eighty
(180) days prior written notice.

            8.03 Either TriVirix or Company may terminate this Agreement for
cause. Cause shall be defined as a material breach or repeated non-material
breaches of this Agreement which are not cured by the breaching party as quickly
as reasonably possible, but in no event longer than sixty (60) days after
receipt of written notice demanding such breaches be cured. Cause shall also
include the following: (a) the failure, cessation, liquidation or dissolution of
the either party's (the "Defaulting Party") business, (b) if the Defaulting
Party makes an assignment for the benefit of creditors, files a petition in
bankruptcy, applies to or petitions any tribunal for the appointment of a
custodian, receiver, intervenor or trustee for such Defaulting Party or a
substantial part of such Defaulting Party's assets; or (c) if the Defaulting
Party shall commence a proceeding under any bankruptcy, rearrangement of debt,
dissolution or liquidation law or statute of any jurisdiction, whether now or
hereafter in effect, or if any such petition or application shall have been
filed or proceeding commenced against the Defaulting Party and the Defaulting
Party shall not have dismissed the same within thirty (30) days, or if such
custodian, receiver, intervenor or trustee shall have been appointed for the
Defaulting Party or such party's properties or assets.

            8.04 If the Agreement is terminated by Company other than for cause,
Company agrees to pay TriVirix, at the time of termination, an amount equal to
TriVirix's standard cost plus a reasonable mark up for any and all production
quality materials in inventory, including WIP or finished goods, or on order for
consumption within the Forecast period that is not cancelable or returnable, and
any restocking fees, that were purchased by TriVirix to manufacture Products
under this Agreement. TriVirix agrees to use its best efforts to cancel or
return such materials in order to mitigate the total cost to the Company.
TriVirix's standard cost shall mean the actual purchase price for a component,
plus the material overhead costs of purchasing, receiving, inspecting and
warehousing the component, and any labor associated with the manufacture of any
subassemblies or finished products. Any materials paid for by the Company
pursuant to this Section 8.04 will be delivered by TriVirix to the Company.

            8.05 Upon termination of this Agreement in accordance with this
Article 8 the DMR and all tooling being used by TriVirix that has been paid for
by Company shall be transferred to Company; provided that if this Agreement is
terminated by TriVirix for Cause,

                                       14
<PAGE>
the Company first pays TriVirix any amounts then owing to TriVirix under this
Agreement. TriVirix shall provide Company with a listing of such tooling within
sixty (60) days of termination, and Company shall advise TriVirix within thirty
(30) days of receipt of such listing the disposition of all such tooling. All
costs directly related to the transfer of such tooling shall be borne by
Company.

                                       15
<PAGE>
                                   ARTICLE IX

                                    INSURANCE

            9.01 During the term of this Agreement, and for a period of seven
(7) years thereafter if on a claims made basis, TriVirix and Company shall carry
and maintain in force (a) comprehensive general liability insurance with
coverage satisfactory to Company, which is at least of the type usually carried
by prudent developers and manufacturers of products similar to the Product(s)
and which covers risks of the kind customarily insured against by such prudent
developers and manufacturers, (b) products liability insurance in an amount not
less than * * * and (c) workers' compensation insurance as required by law. Upon
the execution of this Agreement and at such other times during its term as
Company may request, TriVirix shall provide Company and Company shall provide
TriVirix with a certificate of insurance evidencing such coverage hereof. The
policies required of both parties pursuant to this Agreement shall provide that
they may not be cancelled or changed without at least thirty (30) days notice to
Company from the company providing such insurance. The insurer utilized by both
parties hereunder shall be an insurance company generally providing insurance of
the type required hereunder and shall be reasonably acceptable to the Company.

                                   ARTICLE X

                               GENERAL PROVISIONS

            10.01 Survival. The rights and obligations of Articles 5
(Confidential Information), 6 (License for use of the DMR), 7 (Warranties and
Indemnification), 8 (Term, Termination and Cancellation), 9 (Insurance) and 10
(General Provisions) shall survive any termination of this Agreement and shall
bind the parties and their legal representatives, successors and assigns.

            10.02 Government Approvals. Company shall obtain and shall own the
necessary governmental registrations and permits for marketing the Product(s) in
the United States. In the event of export of the Product(s) by Company or its
Affiliates, Company or its Affiliates shall obtain and own the necessary
governmental registrations and permits for marketing Product(s) in locations
outside the United States. In the event of export of the Product(s) by Company
or its Affiliates or subcontract distributors, Company or its Affiliates or
subcontract distributors shall obtain and own the necessary governmental
registrations and permits for marketing Product(s) in locations outside the
United States.

            10.03 No Consequential Damages. In no event shall either party be
liable for any consequential damages under this Agreement.

                                       16
<PAGE>
            10.04 Audit of Billing Records. Company shall have the right, at its
own expense, during the term of this Agreement and for one (1) year thereafter,
to have an independent public accountant, reasonably acceptable to TriVirix,
examine the relevant financial books and records of account of TriVirix during
normal business hours, upon reasonable notice, to determine or verify the amount
of any amounts billed to the Company under Sections 2.04(a), 2.06, 2.07, 3.04,
8.04 or 8.05. If errors of * * * or more in Company's favor are discovered as a
result of such examination, TriVirix shall reimburse Company for the reasonable
expense of such examination, not to exceed * * *. As a condition to such
examination, the independent public accountant selected by Company shall execute
a written agreement, reasonably satisfactory in form and substance to TriVirix,
to maintain in confidence all information obtained during the course of any such
examination except for disclosure to TriVirix as necessary for the above
purpose.

            10.05 Maintenance of Records. TriVirix shall maintain all
engineering, manufacturing, and inspection records, all records of shipments of
the Products from TriVirix to Company or Company's designees, and all records
related to Product or facility regulations and certifications for the time
periods required by applicable laws and regulations with respect to the
Products. TriVirix shall make such records and data available for review and
copying by Company at TriVirix' facility upon reasonable prior written notice
from Company to TriVirix. In addition, upon termination or expiration of this
Agreement, whichever occurs first, TriVirix will upon Company's request, make
copies of such records and data for Company.

            10.06 Employee Solicitation. During the period beginning with the
date hereof and ending twelve (12) months after all Services to be provided
hereunder have been performed, each of TriVirix and Company, for itself and its
Affiliates, agree that it will not solicit for employment or otherwise interfere
with the employment of any employee except as may be expressly stated in any
Proposal, without the permission of the other Party.

            10.07 Force Majeure.

            (a) Neither Party shall be held liable or responsible for failure or
delay in fulfilling or performing any of its obligations under this Agreement
(other than the payment of money) in case such failure or delay is due to any
condition beyond the reasonable control of the affected Party including, without
limitation, acts of God, strikes or other labor disputes, .governmental
regulations or actions, but excluding failure or delay caused by the affected
Party's negligence or financial condition (a "Force Majeure Event"). Such Party
shall promptly resume performance hereunder as soon as practicable upon the
termination of a Force Majeure Event.

            (b) Each Party agrees to give the other Party prompt written notice
of the occurrence of any Force Majeure Event, the nature thereof, and the extent
to which the affected Party will be unable fully to perform its obligations
hereunder. Each Party further agrees to use commercially reasonable efforts to
correct the Force Majeure Event as quickly as possible and to give the other
Party prompt written notice when it is again fully able to perform such
obligations.

            10.08 Legal Compliance. Each Party shall comply in all material
respects with all laws and regulations applicable to the conduct of its business
pursuant to this Agreement.

                                       17
<PAGE>
            10.09 Press Releases. Any press release, publicity or other form of
public written disclosure related to this Agreement prepared by one Party shall
be submitted to the other Party prior to release for approval, which approval
shall not be unreasonably withheld by such other party.

            10.10 Use of Names. Except as otherwise required by law or by the
terms of this Agreement or mutually agreed upon by the Parties, neither Party
shall make any use of the name of the other Party or any trade name or trademark
belonging to the other Party in any advertising or promotional material without
the prior consent of the other Party, which consent shall not be unreasonably
withheld.

            10.11 Dispute Resolution. The Parties recognize that a bona fide
dispute as to certain matters may from time to time arise during the term of
this Agreement that relates to either Party's rights and/or obligations
hereunder. In the event of the occurrence of such a dispute, either Party may,
by notice to the other Party, have such dispute referred to their respective
officers, or their successors, for attempted resolution by good faith
negotiations within ten (10) days after such notice is received. In the event
the designated officers are not able to resolve such dispute within such ten
(10) day period, or such other period of time as the Parties may mutually agree
in writing, each Party shall have the right to pursue any and all remedies
available at law or in equity.

            10.12 Venue. Any court proceeding initiated by one Party against the
other Party with respect to this Agreement shall be commenced in Delaware;
provided, however, if the court proceeding is brought as a third party action as
part of a pending proceeding in a different venue, either Party may initiate
such third party action against the other Party in such other venue.

            10.13 Independent Contractors. The relationship between Company and
TriVirix is that of independent contractors and nothing herein shall be deemed
to constitute the relationship of partners, joint venturers, nor of principal
and agent between Company and TriVirix. Neither Party shall have any express or
implied right or authority to assume or create any obligations on behalf of or
in the name of the other Party or to bind the other Party to any contract,
agreement or undertaking with any Third Party.

            10.14 Waiver. Neither Party's waiver of any breach or failure to
enforce any of the terms and conditions of this Agreement, at any time, shall in
any way affect, limit or waive such Party's right thereafter to enforce and
compel strict compliance with every term and condition of this Agreement.

            10.15 Severability. Each Party hereby expressly agrees that it has
no intention to violate any public policy, statutory or common laws, rules,
regulations, treaty or decision of any government agency or executive body
thereof of any country or community or association of countries; that if any
word, sentence, paragraph, clause or combination thereof in this Agreement is
found by a court or executive body with judicial powers having jurisdiction over
this Agreement or either Party hereto, in a final unappealed order, to be in
violation of any such provisions in any country or community or association of
countries, such words, sentences, paragraphs, clauses or combination shall be
inoperative in such country or community or

                                       18
<PAGE>
association of countries and the remainder of this Agreement shall remain
binding upon the Parties, so long as enforcement of the remainder does not
violate the Parties' overall intentions in this transaction.

            10.16 Exhibits. All exhibits and Proposals referred to in this
Agreement form an integral part of this Agreement and are incorporated into this
Agreement by such reference.

            10.17 Governing Law; Entire Agreement. The validity, interpretation
and performance of this Agreement shall be governed and construed in accordance
with the laws of Delaware without regard to the conflicts of laws provisions
thereof. This Agreement, the Purchase Order, the proposal and any attachments
constitutes the full understanding of the Parties and a complete and exclusive
statement of the terms of their agreement. No terms, conditions, understanding,
or agreement purporting to modify or vary the terms of this Agreement shall be
binding unless hereafter made in writing and signed by the Party to be bound. No
modification to this Agreement shall be effected by the acknowledgment or
acceptance of any purchase order or shipping instruction forms or similar
documents containing terms or conditions at variance with or in addition to
those set forth herein.

            10.18 Order of Precedence. In the case of any conflict, the
following order of precedence shall apply:

            a)    Agreement

            b)    Purchase Order

            c)    Proposal

                  [It is not the intent of this Agreement to modify the DMR,
                  specifications or acceptance criteria for any Product.]

            10.19 All notices, demands and communications provided for in this
Agreement shall be in writing and shall be deemed effective by a party upon hand
delivery or when mailed, postage prepaid, by registered or certified mail or
when sent by telecopy, to the other party or its copy designee at the respective
addresses listed below, unless and until such address is changed by giving
written notice thereof in like manner.

            To Company:

                  Neoprobe Corporation
                  425 Metro Place North, Suite 300
                  Dublin, Oh 43015
                  Attn: President
                  Fax No.: (614) 793-7520

                                       19
<PAGE>
            To TriVirix:
                  TriVirix International
                  2800 Meridian Parkway, Suite 175
                  Durham, North Carolina 27713
                  Attn.:  Vice President, Business Development
                  Fax No.:  (919) 259-9001

            10.20 Assignment. All provisions contained in this Agreement shall
extend to and be binding upon the parties and their respective successors and
assigns. Without the prior written consent of the other party, neither party may
assign, transfer or convey any of its rights, duties or interest under this
Agreement, nor shall it delegate any of the obligations or duties required to be
kept or performed by it hereunder; provided, however, that either party
("Assignor") may, without such consent, assign this Agreement to (i) any of
Assignor's Affiliates (provided, however, such assignment shall not relieve
Assignor of any of its obligations hereunder) or (ii) a successor in interest of
Assignor by merger or operation of law or (iii) a purchaser of all of Assignor's
assets provided such purchaser shall have agreed in writing to perform all of
Assignor's obligations under this Agreement.

            10.21 Counterparts. This Agreement may be executed in one or more
counterparts, all of which taken together shall constitute one and the same
instrument.

            IN WITNESS WHEREOF, the parties hereto have caused this Agreement to
be executed by their duly authorized representatives as of the date first above
written.

                                          NEOPROBE CORPORATION

                                          By: /s/ David C. Bupp
                                              ---------------------------------
                                              Name:  David Bupp
                                              Title: President & CEO

                                          TRIVIRIX INTERNATIONAL

                                          By: /s/ Tom L. Larrichio
                                              ---------------------------------
                                              Name:  Tom L. Larrichio
                                              Title: V. P. Business Development

                                       20
<PAGE>
                                  SCHEDULE 1.12

                                   PRODUCT(S)

<TABLE>
<CAPTION>
NEOPROBE MODEL #      TRIVIRIX MODEL #           DESCRIPTION
----------------      ----------------           -----------
<S>                   <C>                  <C>
      2200                                   neo2000 control unit
      1017                                       14 mm probe
      2059                                 11 mm laparoscopic probe
    CSN00100                               Quantix/OR control unit
    CNS00150                               Quantix/ND control unit
</TABLE>

                                       21
<PAGE>
                                  SCHEDULE 2.05
                            BILL & HOLD ARRANGEMENTS

Company hereby requests that TriVirix store Products of the types listed in
Schedule 1.11 that have been finished, certified complete, packaged and
palletized subject to the maximum quantities listed herein and paid for by
Company. With respect to Products stored under the terms of this Agreement,
Company agrees:

-     to accept title to the Product upon delivery by TriVirix of the Product
      into storage;

-     upon delivery by TriVirix of the Product into storage, to accept the risk
      of insuring the Product against casualty loss not caused by negligence on
      the part of TriVirix; and,

-     acknowledges that from and after the delivery by TriVirix of Products into
      storage, TriVirix has no further performance obligations with respect to
      stored Product beyond the standard product warranty as specified in the
      Agreement. Specifically, and not by way of limitation, Company agrees not
      to hold TriVirix responsible for making any upgrades or modifications to
      stored product that was previously certified based on changes made to
      Product Specifications in the DMR subsequent to the manufacture and
      certification of such product without prior written agreement with
      TriVirix to upgrade or modify said units; and,

TriVirix agrees:

-     to store designated Product separately from other incomplete products or
      completed products TriVirix may choose to manufacture that are in excess
      of Company's purchase commitments;

-     to provide storage facilities that fully comply with storage requirements
      for medical devices as specified in ISO13488 and U.S. FDA 21C.F.R.
      Section820;

-     to periodically provide and/or update certain details regarding the
      facility in which the Products to be stored: address, type of building
      construction [i.e., brick, wooden frame, metal siding], fire protection
      [i.e., sprinkler system, proximity to nearest fire department]); and

-     not to ship Product that has been stored without written instruction from
      an authorized representative of Company.

                                       22
<PAGE>
                                  SCHEDULE 3.01

                                   PRICE LIST

COMMERCIAL YEAR ONE

<TABLE>
<CAPTION>
                 Neoprobe
 Description     Model No.     * * *         * * *        * * *        * * *)
<S>              <C>           <C>           <C>          <C>          <C>
   neo2000         2200        * * *         * * *        * * *        * * *

  14mm probe       1017        * * *         * * *        * * *        * * *

  Quantix/OR     CSN00100      * * *         * * *        * * *        * * *
 control unit

  Quantix/ND     CSN00150      * * *         * * *        * * *        * * *
 control unit
</TABLE>

(1) * * *

(2) * * *

(3) * * *

(4) * * *

COMMERCIAL YEARS TWO AND THREE

Prices for Product for Commercial Years Two and Three will be based on the
following pricing formula at the relative volumes based on the estimated annual
volumes:

<TABLE>
<CAPTION>
                 Neoprobe Model  Potential       Material        G&A and Profit
Description      No.             Annual Volumes  Burden Rate     Rate
-----------      --------------  --------------  -----------     ----
<S>              <C>             <C>             <C>             <C>
neo2000          2200            * * *           * * *           * * *

14mm probe       1017            * * *           * * *           * * *

Quantix/OR                       * * *           * * *           * * *

Quantix/OR                       * * *           * * *           * * *

Quantix/OR                       * * *           * * *           * * *

Quantix/ND                       * * *           * * *           * * *

Quantix/ND                       * * *           * * *           * * *

Quantix/ND                       * * *           * * *           * * *
</TABLE>

                                       23

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