Document:

Exhibit 10.12

 

NON-DISCLOSURE, NON-SOLICITATION
AND NON-COMPETITION AGREEMENT

 

THIS AGREEMENT is made as of this
1st day of January, 2006

 

BETWEEN:

 

CANNASAT THERAPEUTICS INC.

(together with its present and future
parent company, affiliates and subsidiaries)

(hereinafter called the "Corporation")

 

- and -

 

ANDREW WILLIAMS

(hereinafter called the "Employee").

 

WHEREAS the Corporation is in the
business of researching and developing novel pharmaceutical products that target the endocannabinoid system;

 

AND WHEREAS it would be to the detriment
of the Corporation if the Employee were to become associated with a competitor of the Corporation, to solicit or accept remuneration
from clients of the Corporation, solicit or hire employees of the Corporation or to disclose confidential information of the Corporation;

 

NOW THEREFORE THIS AGREEMENT WITNESSETH
THAT in consideration of the mutual covenants and agreements contained herein and other good and valuable consideration, the
receipt and sufficiency of which are hereby acknowledged, the parties hereby agree as follows:

 

1.                            Confidential
Information

 

(a)            Confidential
Information is a Valuable Company Asset. The Corporation’s Confidential Information (defined below) is a valuable, special
and unique asset of the Corporation’s business, access to and knowledge of which are essential to the performance of Employee’s
duties as a team member at the Corporation. It is vital to the Corporation’s legitimate business interests that the confidentiality
of all Confidential Information be preserved. Use or reliance on the Confidential Information by or on behalf of any other business
or commercial activity in competition with the Corporation could result in irreparable harm to the Corporation.

 

(b)            Corporation
Information. The Employee agrees to hold in strict confidence, and not to use, except for the benefit of the Corporation, or
to disclose to any person, firm or corporation without written authorization of the Board of Directors of the Corporation, any
Confidential Information of the Corporation, and such agreement with respect to Confidential Information shall remain in effect
at all times during the term of his or her employment and at any time thereafter.

 

     

     

    

 

(c)            "Confidential
Information" Defined. Employee understands that "Confidential Information" means any and all information and
knowledge regarding the business of the Corporation which the Employee assimilates or to which the Employee has access during his
or her employment with the Corporation including, but not limited to, information about the Corporation's proprietary methods,
methodologies and disciplines, technical data, trade secrets, know-how, research and development information, product plans, products,
services, clients and prospective clients as identified from time to time in the records of the Corporation, client information,
employees, books and records of the Corporation, corporate relationships, suppliers, markets, computer software, computer software
development, inventions, processes, formulas, technology, designs, business plans, and matters of a business nature such as information
regarding marketing, recruiting, costs, pricing, finances, financial models and projections or other similar business information.
Employee further understands that Confidential Information does not include any of the foregoing items which has become publicly
known and made generally available through no act of Employee. Employee further agrees that all Confidential Information shall
at all times remain the property of the Corporation.

 

(d)            Former Employer
Information. Employee represents and warrants that the execution of this Agreement and performance of the Employee’s
obligations hereunder will not conflict with, result in the breach of any provision of, or the termination of or constitute a default
under any agreement with any other person or entity of which the Employee is a party or by which the Employee is bound. Furthermore,
Employee agrees that he or she will not, during his or her employment with the Corporation, improperly use or disclose any proprietary
information or trade secrets of any former employer or other person or entity with which Employee has an agreement or duty to keep
in confidence and that Employee will not bring onto the premises of the Corporation any unpublished document or proprietary information
belonging to any such employer, person or entity unless consented to in writing by such employer, person or entity.

 

(e)            Third Party
Information. Employee recognizes that the Corporation has received and in the future will receive from third parties their
confidential or proprietary information subject to a duty on the Corporation’s part to maintain the confidentiality of such
information and to use it only for certain limited purposes. Employee agrees to hold all such confidential or proprietary information
in the strictest confidence and not to disclose it to any person, firm or corporation or to use it except as necessary in carrying
out his or her work for the Corporation.

 

(f)            Corporation
Property. Employee agrees that all documents, materials, software, or other media, or information of any kind concerning any
matters affecting or relating, directly or indirectly, to the Corporation’s business, products or services (collectively,
"Media"), whether or not they contain or embody Confidential Information, and all Confidential Information are the exclusive
property of the Corporation. Employee agrees to exercise care in accessing, storing and disposing of Media, particularly when it
includes Confidential Information. Immediately upon any termination of Employee’ s employment or at any time upon the request
of the Corporation, Employee agrees to deliver to the Corporation all Media then in his or her possession or control. If the Media
cannot be reasonably delivered, the Employee agrees to provide reasonable evidence that the Media has been destroyed, including
but not limited to, purging or erasing any computer files or data records, provided, however that Employee will not destroy or
discard any Media without prior authorization from the Corporation.

 

    	 	- 2 -	 

     

    

 

(g)            Acknowledgement
of Fiduciary Duty. Employee acknowledges that he or she is a fiduciary of the Corporation and owes the Corporation a duty to
act in the best interests of the Corporation at all times during his or her employment and for a reasonable period of time following
the termination for any reason of his or her employment. Without limiting any provision, covenant or restriction in this Agreement,
the Employee acknowledges that he or she shall not use or assist in the use of any Confidential Information or Media for the Employee’s
personal benefit or the benefit of a third party.

 

2.                            Inventions

 

(a)           Inventions Retained
and Licensed. Employee has attached hereto as Schedule "A" a list describing all inventions, original works of authorship,
developments, improvements, and trade secrets, if any, which:

 

		(i)	were made by him or her prior to his or her employment with the Corporation,

 

		(ii)	which belong to him or her, and

 

		(iii)	which relate to the Corporation’s current or anticipated business, products or services (collectively
referred to as "Prior Inventions").

 

The Prior Inventions are not being assigned
to the Corporation hereunder. If no such list is attached, Employee represents that there are no such Prior Inventions. If in the
course of his or her employment with the Corporation, Employee incorporates a Prior Invention owned by him or her or in which Employee
has an interest into a Corporation product, process, client deliverable or machine:

 

		(A)	the Corporation is hereby granted and shall have a non-exclusive, royalty-free, irrevocable, perpetual,
worldwide license to make, have made, modify, use, copy, sublicense and sell such Prior Invention as part of or in connection with
such product, process, client deliverable or machine, and

 

		(B)	Employee shall not have any right, title or interest in or to such the Corporation product, process,
client deliverable or machine.

 

(b)            Assignment
of Inventions. Employee agrees to promptly make full written disclosure to the Corporation and will hold in trust for the sole
right and benefit of the Corporation, and Employee hereby assigns to the Corporation, or its designee, all Employee’s right,
title and interest in and to any and all Inventions (defined below). Employee understands and agrees that "Inventions"
means any ideas, discoveries, know-how, innovations, writings, works of authorship, drawings, designs, inventions, trade secrets,
business plans, developments and improvements, whether or not patentable or registrable under copyright or similar laws, or reduced
to practice or writing, which Employee solely or jointly conceives or develops during the period Employee is employed by the Corporation
or reduces to practice either during employment by the Corporation or within one year thereafter, and which:

 

    	 	- 3 -	 

     

    

 

		(i)	relate to the Corporation’s current or anticipated business, products or services; or

 

		(ii)	are based on any Confidential Information; or

 

		(iii)	are developed

 

		(A)	at or using the Corporation’s or a Corporation or client project’s facilities,

 

		(B)	in conjunction with a Corporation project, or

 

		(C)	using the Corporation Media or computer or communications systems.

 

(c)            Waiver of Rights.
The Employee waives all moral rights in the Inventions.

 

(d)            Maintenance
of Records. Employee agrees to keep and maintain adequate and current written records of all Inventions made by Employee (solely
or jointly with others) during the term of Employee’s employment with the Corporation. The records will be available to and
remain the sole property of the Corporation at all times.

 

(e)            Patent and
Copyright Registrations. Employee agrees to assist the Corporation, or its designee, at the Corporation’s expense, in
every proper way to secure the Corporation’s rights in the Inventions and any copyrights, patents or other intellectual property
rights relating thereto in any and all countries, including the disclosure to the Corporation of all pertinent information and
data with respect thereto and the execution of all applications, specifications, oaths, assignments and all other instruments which
the Corporation shall deem necessary in order to apply for and obtain such rights and in order to assign and convey to the Corporation,
its successors, assigns and nominees the sole and exclusive rights, title and interest in and to such Inventions, and any copyrights,
patents or other intellectual property rights relating thereto.

 

3.                            Solicitation
of Employees

 

Employee recognizes and agrees that the
Corporation employees must by the nature of their jobs have access to Confidential Information, that the Corporation invests in
its employees by making specialized training available to them and that the Corporation has a legitimate interest in protecting
its employee relationships and in maintaining a stable workforce. During the Employee’s employment with the Corporation and
for a period of two years following the termination of his or her employment with the Corporation, for any reason, Employee agrees
to refrain from and will not, directly or indirectly, as an independent contractor, employee, consultant, agent, partner, joint
venturer or otherwise solicit or attempt to solicit or assist another person in the solicitation of employees of the Corporation,
either for Employee’s own business or for any other person or entity.

 

    	 	- 4 -	 

     

    

 

4.                            Covenants
Against Solicitation of Clients.

 

Employee agrees that the Corporation has
a legitimate interest in protecting its client relationships. During the Employee’s employment with the Corporation and for
a period of one year following the termination of his or her employment with the Corporation, for any reason, Employee agrees to
refrain from and will not, directly or indirectly, accept business from, solicit, divert or take away, or attempt to accept business
from, solicit, divert or take away, the business or patronage of any of the clients of the Corporation which were contacted, solicited,
supervised or served by the Employee during his or her employment or with which Employee had contact during his or her employment.

 

5.                            Covenants
Against Employment with Clients or Competitors.

 

EMPLOYEE ACKNOWLEDGES AND UNDERSTANDS THAT
THIS SECTION MAY AFFECT HIS OR HER RIGHT TO ACCEPT EMPLOYMENT WITH OTHER COMPANIES SUBSEQUENT TO EMPLOYMENT BY CORPORATION. Employee
acknowledges and agrees that the Corporation operates its business in a highly competitive environment, that the Corporation employees
must by the nature of their jobs have access to Confidential Information and that the Corporation invests in its employees by making
specialized training available to them.

 

(a)          Clients.
As a material inducement for the Corporation to employ or to continue to employ the Employee, as the case may be, and in order
to protect the Corporation’s Confidential Information and goodwill, Employee agrees that during the time the Employee is
employed by the Corporation and for a period of one year after termination of Employee’s employment with the Corporation,
for any reason, Employee shall not, directly or indirectly, without the prior written consent of the Corporation, provide services
to, accept employment with or seek remuneration from any of the clients or customers of the Corporation or any entity controlled
by, controlling or under common control with, any client or customer of the Corporation. For purposes of this Section 5(a),
a client or customer of the Corporation shall be defined as any person, firm, partnership, corporation or other entity with
or to whom the Corporation, as of the date of Employee’s termination of employment or during the one year prior to the termination
of employment of Employee:

 

		(i)	sold goods or services,

 

		(ii)	had submitted a written proposal for a specific requirement, or

 

		(iii)	had work in progress.

 

    	 	- 5 -	 

     

    

 

(b)          Competitors.
As a material inducement for the Corporation to employ or to continue to employ the Employee, or as the case may be, and in order
to protect the Corporation’s Confidential Information and goodwill, Employee agrees that during the time the Employee is
employed by the Corporation and for a period of one year after termination of Employee’s employment with the Corporation,
for any reason, Employee shall not, directly or indirectly, without the prior written consent of the Corporation, assist with the
creation of any Competing Organization (as that term is defined below).

 

(c)          "Competing
Organization" Defined. For the purposes of this Section 5, a "Competing Organization" means any
person or organization which is engaged in or is about to become engaged in a business which is identical or substantially similar
to the Corporation’s business. As of the date of this Agreement, Competing Organizations include, but are not limited to
GW Pharmaceuticals, Kadmus Pharmaceuticals, Pharmos Corporation, Solvay Pharmaceuticals and Sanofi Aventis (cannabinoid group/division
only). Employee acknowledges and understands that the foregoing list of Competing Organizations may change from time to time and
that such list is not exhaustive,

 

(d)          Modification
of Restrictions in Sections 3, 4 or 5 by Court. Employee acknowledges that he or she has carefully read and considered all
the terms and conditions of this Agreement, including the restrictions imposed upon him or her pursuant to Sections 3, 4 or 5.
Employee agrees that the restrictions set forth in Sections 3, 4 and 5 are fair and reasonable and are reasonably required
for the protection of the interests of the Corporation. However, should a court nonetheless determine at a later date that such
restrictions are unreasonable in light of the circumstances as they then exist, then Employee agrees that Sections 3, 4 or 5
(or any combination of them) shall be construed in such a manner as to impose on Employee such restrictions as may then be
reasonable and sufficient to assure the Corporation of the intended benefits of the Section in question.

 

(e)          Possible Extension
of Time Period. The time period during which the Employee is prohibited from engaging in certain business practices pursuant
to Sections 3, 4 and 5 may by order of a court be extended by any length of time during which the Employee is in breach
of such covenants.

 

(f)          New Terms in
the event of Role Change. Employee agrees that if his or her role changes to that of a Vice President or any other role which
in the Corporation’s discretion requires the protection of a longer time period for the obligations contained in Section
5(b), then in order for such role change to become effective, and in consideration of the Employee’s promotion to such role
and the increased exposure to the Corporation confidential information, business know-how and the Corporation clients that is attendant
upon such promotion, Employee will sign a new agreement with the Corporation or amendment to this Agreement pursuant to which the
obligations contained in Section 5(b) will apply for 12 months after termination of employment. The foregoing shall not
create any right to or expectation of any role change.

 

    	 	- 6 -	 

     

    

 

6.                            General Provisions

 

(a)          Governing Law.
This Agreement will be governed by the laws of the Province of Ontario.

 

(b)          Entire Agreement:
Approvals or Consents; Modifications. The Agreement sets forth the entire agreement and understanding between the Corporation
and Employee relating to the subject herein and supersedes all prior discussions and agreements with respect hereto. Any subsequent
change or changes in Employee’s duties, role, salary or compensation will not affect the validity or scope of this Agreement.
In any instance under this Agreement in which the authorization, consent or approval by the Corporation is required or can be given,
such authorization, consent or approval:

 

		(i)	may be given, withheld or conditioned in the Corporation’s sole discretion, and

 

		(ii)	to be effective must be in writing and signed by the President or a Director unless specifically
provided otherwise in this Agreement.

 

No modification of or amendment to this
Agreement, nor any waiver of any rights under this Agreement, will be effective unless in writing signed by both parties.

 

(c)          Severability.
If one or more of the provisions in this Agreement are deemed void by law, then the remaining provisions will continue in full
force and effect.

 

(d)          Successors
and Assigns. This Agreement will be binding upon Employee’s heirs, executors, administrators and other legal representatives
and will be for the benefit of the Corporation, its successors and assigns.

 

(e)          Enforcement
in Accordance with Law. The parties agree that this Agreement will be enforced in accordance with applicable law.

 

(f)          Waiver of Breach.
The waiver by the Corporation of a breach of any of the provisions of this Agreement by the Employee shall not be construed as
a waiver by the Corporation of any subsequent breach by the Employee.

 

(g)          Equitable Relief.
The Employee acknowledges and agrees that a breach of any provision of this Agreement will cause irreparable damage to the Corporation,
and that such breach, the Corporation shall be entitled to equitable relief, including injunctive relief and specific performance,
without the necessity of providing actual damages, and shall be further entitled to an accounting of all earnings, profits or other
benefits acquired by the Employee as a result of such breach, and to any other remedy now or hereafter provided at law for such
breach.

 

(h)          Independent
Legal Advice. The Employee confirms that he or she has been afforded an opportunity to obtain independent legal advice regarding
the terms of this Agreement. Further, it is confirmed by Employee that he or she has entered this Agreement freely, voluntarily
and without duress.

 

    	 	- 7 -	 

     

    

 

	
        SIGNED,
        SEALED & DELIVERED

        in the presence of:
	 	
        )

        )

        )

        )
	
         

        

	/s/ Angeline Zoupas	 	)	/s/ Andrew Williams
	Witness	 	)	Andrew Williams

 

	 	CANNASAT THERAPEUTICS INC.
	 	 
	 	Per:	/s/ David Hill
	 	 	Authorized Signing Officer

 

    	 	- 8 -Exhibit 10.13

 

NON-DISCLOSURE, NON-SOLICITATION AND
NON-COMPETITION AGREEMENT

 

THIS
AGREEMENT is made as of this 6th day of October, 2014.

 

BETWEEN:

 

CYNAPSUS THERAPEUTICS INC.

 

(hereinafter called the “Corporation”)

 

- and -

 

THIERRY BILBAULT

 

(hereinafter called the “Executive”)

 

WHEREAS the Corporation is a specialty
pharmaceutical company developing a drug to treat the motor symptoms of Parkinson’s disease;

 

AND WHEREAS it would be to the
detriment of the Corporation if the Executive were to become associated with a competitor of the Corporation, to solicit or accept
remuneration from clients or suppliers of the Corporation, solicit or hire employees of the Corporation or to disclose confidential
information of the Corporation;

 

NOW THEREFORE THIS AGREEMENT WITNESSES
THAT in consideration of the mutual covenants and agreements contained herein and other good and valuable consideration, the
receipt and sufficiency of which are hereby acknowledged, the parties hereby agree as follows:

 

1.                           Confidential
Information

 

(a)          Confidential
Information is a Valuable Company Asset. The Corporation’s Confidential Information (as defined below) is a valuable,
special and unique asset of the Corporation’s business and is essential to the performance of the Executive’s duties
as a team member at the Corporation. It is vital to the Corporation’s legitimate business interests that the confidentiality
of all Confidential Information be preserved. Use or reliance on the Confidential Information by or on behalf of any other business
or commercial activity in competition with the Corporation could result in irreparable harm to the Corporation.

 

(b)          Corporation
Information. The Executive agrees to hold in strict confidence, and not to use, except for the benefit of the Corporation,
or to disclose to any person, firm or corporation without written authorization of the Board of Directors of the Corporation, any
Confidential Information of the Corporation, and such agreement with respect to Confidential Information shall remain in effect
at all times during the term of his employment and at any time thereafter.

 

     

     

    

 

(c)          “Confidential
Information” Defined. The Executive understands that “Confidential Information” means any and all information
and knowledge regarding the business of the Corporation which the Executive assimilates or to which the Executive has access during
his employment with the Corporation including, but not limited to, information about the Corporation’s proprietary methods,
methodologies and disciplines, technical data, trade secrets, know-how, research and development information, product plans, products,
services, clients and prospective clients as identified from time to time in the records of the Corporation, client information,
employees, books and records of the Corporation, corporate relationships, suppliers, markets, computer software, computer software
development, inventions, processes, formulas, technology, designs, business plans, and matters of a business nature such as information
regarding marketing, recruiting, costs, pricing, finances, financial models and projections or other similar business information.
The Executive further understands that Confidential Information does not include any of the foregoing items which has become publicly
known and made generally available through no act of the Executive. The Executive further agrees that all Confidential Information
shall at all times remain the property of the Corporation. The term “Confidential Information” will not, however, include
information which (i) is or becomes publicly available other than as a result of a disclosure by the Executive, or (ii) is or becomes
available to the Executive on a non-confidential basis from a source (other than by the Corporation or a representative of the
Corporation) that is not prohibited from disclosing such information to the Executive by a legal, contractual or fiduciary obligation
to the Corporation.

 

(d)          Former
Employer Information. The Executive represents and warrants that the execution of this Agreement and performance of the Executive’s
obligations hereunder will not conflict with, result in the breach of any provision of, or the termination of or constitute a default
under any agreement with any other person or entity of which the Executive is a party or by which the Executive is bound. Furthermore,
the Executive agrees that he will not, during his employment with the Corporation, improperly use or disclose any proprietary information
or trade secrets of any former employer or other person or entity with which the Executive has an agreement or duty to keep in
confidence and that the Executive will not bring onto the premises of the Corporation any unpublished document or proprietary information
belonging to any such employer, person or entity unless consented to in writing by such employer, person or entity.

 

(e)          Third
Party Information. The Executive recognizes that the Corporation has received and in the future will receive from third parties
their confidential or proprietary information subject to a duty on the Corporation’s part to maintain the confidentiality
of such information and to use it only for certain limited purposes. The Executive agrees to hold all such confidential or proprietary
information in the strictest confidence and not to disclose it to any person, firm or corporation or to use it except as necessary
in carrying out his work for the Corporation.

 

    	 	- 2 -	 

     

    

 

(f)          Corporation
Property. The Executive agrees that all documents, materials, software, or other media, or information of any kind concerning
any matters affecting or relating, directly or indirectly, to the Corporation’s business, products or services (collectively,
“Media”), whether or not they contain or embody Confidential Information, and all Confidential Information are the
exclusive property of the Corporation. The Executive agrees to exercise care in accessing, storing and disposing of Media, particularly
when it includes Confidential Information. Immediately upon any termination of the Executive’s employment or at any time
upon the request of the Corporation, the Executive agrees to deliver to the Corporation all Media then in his possession or control.
If the Media cannot be reasonably delivered, the Executive agrees to provide reasonable evidence that the Media has been destroyed,
including but not limited to, purging or erasing any computer files or data records, provided, however that the Executive will
not destroy or discard any Media without prior authorization from the Corporation. The term “Media” will not, however,
include information which (i) is or becomes publicly available other than as a result of a disclosure by the Executive, or (ii)
is or becomes available to the Executive on a non-confidential basis from a source (other than by the Corporation or a representative
of the Corporation) that is not prohibited from disclosing such information to the Executive by a legal, contractual or fiduciary
obligation to the Corporation.

 

(g)          Acknowledgement
of Fiduciary Duty. The Executive acknowledges that he is a fiduciary of the Corporation and owes the Corporation a duty to
act in the best interests of the Corporation at all times during his employment and for a reasonable period of time following the
termination for any reason of his employment. Without limiting any provision, covenant or restriction in this Agreement, the Executive
acknowledges that he shall not use or assist in the use of any Confidential Information or Media for the Executive’s personal
benefit or the benefit of a third party.

 

2.                           Inventions

 

(a)          Inventions
Retained and Licensed. The Executive has attached hereto as Schedule “A” a list describing all inventions, original
works of authorship, developments, improvements and trade secrets, if any, which:

 

		(i)	were made by him prior to his employment with the Corporation,

 

		(ii)	which belong to him, and

 

		(iii)	which relate to the Corporation’s current or anticipated
business, products or services (collectively referred to as “Prior Inventions”).

 

The Prior Inventions
are not being assigned to the Corporation hereunder. If no such list is attached, the Executive represents that there are no such
Prior Inventions. If in the course of his employment with the Corporation, the Executive incorporates a Prior Invention owned by
him or in which the Executive has an interest into a Corporation product, process, client deliverable or machine:

 

		(A)	the Corporation is hereby granted and shall have a nonexclusive,
royalty-free, irrevocable, perpetual, worldwide license to make, have made, modify, use, copy, sublicense and sell such Prior
Invention as part of or in connection with such product, process, client deliverable or machine, and

 

    	 	- 3 -	 

     

    

 

		(B)	the Executive shall not have any right, title or interest
in or to such the Corporation product, process, client deliverable or machine.

 

(b)          Assignment
of Inventions. The Executive agrees to promptly make full written disclosure to the Corporation and will hold in trust for
the sole right and benefit of the Corporation, and the Executive hereby assigns to the Corporation, or its designee, all the Executive’s
right, title and interest in and to any and all Inventions (defined below). The Executive understands and agrees that “Inventions”
means any ideas, discoveries, know-how, innovations, writings, works of authorship, drawings, designs, inventions, trade secrets,
business plans, developments and improvements, whether or not patentable or registrable under copyright or similar laws, or reduced
to practice or writing, which the Executive solely or jointly conceives, develops or reduces to practice during the period the
Executive is employed by the Corporation, and which:

 

		(i)	relate to the Corporation’s current or anticipated
business, products or services; or

 

		(ii)	are based on any Confidential Information; or

 

		(iii)	are developed:

 

		(A)	at or using the Corporation’s or a Corporation or
client project’s facilities;

 

		(B)	in conjunction with a Corporation project; or

 

		(C)	using the Corporation Media or computer or communications
systems.

 

(c)          Waiver
of Rights. The Executive waives all moral rights in or to the Inventions.

 

(d)          Maintenance
of Records. The Executive agrees to keep and maintain adequate and current written records of all Inventions made by the Executive
(solely or jointly with others) during the term of the Executive’s employment with the Corporation. The records will be available
to and remain the sole property of the Corporation at all times.

 

(e)          Patent
and Copyright Registrations. The Executive agrees to assist the Corporation, or its designee, at the Corporation’s expense,
in every proper way to secure the Corporation’s rights in and to the Inventions and any copyrights, patents or other intellectual
property rights relating thereto in any and all countries, including the disclosure to the Corporation of all pertinent information
and data with respect thereto and the execution of all applications, specifications, oaths, assignments and all other instruments
which the Corporation shall deem necessary in order to apply for and obtain such rights and in order to assign and convey to the
Corporation, its successors, assigns and nominees the sole and exclusive right, title and interest in and to such Inventions, and
any copyrights, patents or other intellectual property rights relating thereto. 

 

    	 	- 4 -	 

     

    

 

3.                           Solicitation
of Employees

 

The Executive recognizes and agrees that
the Corporation’s employees must by the nature of their jobs have access to Confidential Information, that the Corporation
invests in its employees by making specialized training available to them and that the Corporation has a legitimate interest in
protecting its employee relationships and in maintaining a stable workforce. During the Executive’s employment with the Corporation
and for a period of two years following the termination of his employment with the Corporation, for any reason, the Executive agrees
to refrain from and will not, directly or indirectly, as an independent contractor, employee, consultant, agent, partner, joint
venture or otherwise solicit or attempt to solicit or assist another person in the solicitation of employees of the Corporation,
either for the Executive’s own business or for any other person or entity.

 

4.                           Covenants
Against Solicitation of Clients.

 

The Executive agrees that the Corporation
has a legitimate interest in protecting its client and supplier relationships. During the Executive’s employment with the
Corporation and for a period of one year following the termination of his employment with the Corporation, for any reason (the
“Non-Competition Period”), the Executive agrees to refrain from and will not, directly or indirectly, accept business
from, solicit, divert or take away, or attempt to accept business from, solicit, divert or take away, the business or patronage
of any of the clients or suppliers of the Corporation which were contacted, solicited, supervised or served by the Executive during
his employment or with which the Executive had contact during his employment (each, a “Client”). Notwithstanding the
foregoing, and for greater clarity, during the Non-Competition Period, the Executive will be entitled to accept business from a
Client provided that it does not involve or relate to a Competitive Business Activity. For the purposes of this Agreement, the
term “Competitive Business Activity” shall mean the development or production of pharmaceutical products to treat the
motor symptoms of Parkinson’s disease.

 

5.                           Covenants
Against Employment with Clients or Competitors.

 

THE EXECUTIVE ACKNOWLEDGES AND UNDERSTANDS
THAT THIS SECTION MAY AFFECT HIS RIGHT TO ACCEPT EMPLOYMENT WITH OTHER COMPANIES SUBSEQUENT TO EMPLOYMENT BY THE CORPORATION. The
Executive acknowledges and agrees that the Corporation operates its business in a highly competitive environment, that the Corporation’s
employees must by the nature of their jobs have access to Confidential Information and that the Corporation invests in its employees
by making specialized training available to them.

 

    	 	- 5 -	 

     

    

 

(a)          Clients.
As a material inducement for the Corporation to employ or to continue to employ the Executive, as the case may be, and in order
to protect the Corporation’s Confidential Information and goodwill, the Executive agrees that during the time the Executive
is employed by the Corporation, and during the Non-Competition Period, the Executive shall not, directly or indirectly, without
the prior written consent of the Corporation, provide services to, accept employment with or seek remuneration from any Client
or any entity controlled by, controlling or under common control with, any Client. Notwithstanding the foregoing, and for greater
clarity, during the Non-Competition Period, the Executive shall be permitted to (A) provide services to or seek remuneration from
any Client, provided that the services rendered do not involve or relate to a Competitive Business Activity, and (B) accept employment
with any Client, provided that such Client is not engaged in a Competitive Business Activity.

 

(b)          Competitors.
As a material inducement for the Corporation to employ or to continue to employ the Executive, or as the case may be, and in order
to protect the Corporation’s Confidential Information and goodwill, the Executive agrees that during the time the Executive
is employed by the Corporation and during the Non-Competition Period, the Executive shall not, directly or indirectly, without
the prior written consent of the Corporation:

 

		(i)	assist with the creation of any Competing Organization
(as below); or

 

		(ii)	within a 150 kilometre radius of the Corporation’s
office or any location where the Executive has performed services for the Corporation, render services as an employee, consultant
or otherwise to any Competing Organization.

 

(c)          “Competing
Organization” Defined. For the purposes of this Section 5, a “Competing Organization” means any person
or organization which is engaged in or is about to become engaged in a Competitive Business Activity.

 

(d)          Modification
of Restrictions in Sections 3, 4 or 5 by Court. The Executive acknowledges that he has carefully read and considered all the
terms and conditions of this Agreement, including the restrictions imposed upon him pursuant to Sections 3, 4 or 5. The Executive
agrees that the restrictions set forth in Sections 3, 4 and 5 are fair and reasonable and are reasonably required for the
protection of the interests of the Corporation. However, should a court nonetheless determine at a later date that such restrictions
are unreasonable in light of the circumstances as they then exist, then the Executive agrees that Sections 3, 4 or 5 (or any combination
of them) shall be construed in such a manner as to impose on the Executive such restrictions as may then be reasonable and sufficient
to assure the Corporation of the intended benefits of the Section in question.

 

(e)          Possible
Extension of Time Period. The time period during which the Executive is prohibited from engaging in certain business practices
pursuant to Sections 3, 4 and 5 may by order of a court be extended by any length of time during which the Executive is in breach
of such covenants.

 

    	 	- 6 -	 

     

    

 

6.                           General
Provisions

 

(a)          Governing
Law. This Agreement will be governed by the laws of the Province of Ontario.

 

(b)          Entire
Agreement: Approvals or Consents; Modifications. This Agreement, together with the Executive’s employment agreement with
the Corporation dated the date hereof, sets forth the entire agreement and understanding between the Corporation and the Executive
relating to the subject herein and supersedes all prior discussions and agreements with respect hereto. Any subsequent change or
changes in the Executive’s duties, role, salary or compensation will not affect the validity or scope of this Agreement.
In any instance under this Agreement in which the authorization, consent or approval by the Corporation is required or can be given,
such authorization, consent or approval:

 

		(i)	may be given, withheld or conditioned in the Corporation’s
sole discretion; and

 

		(ii)	to be effective must be in writing and signed by the President
or a Director unless specifically provided otherwise in this Agreement.

 

No modification of or amendment to this
Agreement, nor any waiver of any rights under this Agreement, will be effective unless in writing signed by both parties.

 

(c)          Severability.
If one or more of the provisions in this Agreement are deemed void by law, then the remaining provisions will continue in full
force and effect.

 

(d)          Successors
and Assigns. This Agreement will be binding upon the Executive’s heirs, executors, administrators and other legal representatives
and will be for the benefit of the Corporation, its successors and assigns.

 

(e)          Enforcement
in Accordance with Law. The parties agree that this Agreement will be enforced in accordance with applicable law.

 

(f)          Waiver
of Breach. The waiver by the Corporation of a breach of any of the provisions of this Agreement by the Executive shall not
be construed as a waiver by the Corporation of any subsequent breach by the Executive.

 

(g)          Equitable
Relief. The Executive acknowledges and agrees that a breach of any provision of this Agreement will cause irreparable damage
to the Corporation, and that such breach, the Corporation shall be entitled to equitable relief, including injunctive relief and
specific performance, without the necessity of providing actual damages, and shall be further entitled to an accounting of all
earnings, profits or other benefits acquired by the Executive as a result of such breach, and to any other remedy now or hereafter
provided at law for such breach.

 

(h)          Independent
Legal Advice. The Executive confirms that he has been afforded an opportunity to obtain independent legal advice regarding
the terms of this Agreement. Further, it is confirmed by the Executive that he has entered this Agreement freely, voluntarily and
without duress.

 

[ Signature Page Follows ]

 

    	 	- 7 -	 

     

    

 

	SIGNED, SEALED & DELIVERED	 	)	 
	in the presence of:	 	)	 
	 	 	)	 
	 	 	)	 
	 	 	)	 
	/s/ Andrew Williams	 	)	/s/  Thierry Bilbault
	Witness	 	 	THIERRY BILBAULT

 

	 	CYNAPSUS THERAPEUTICS INC.
	 	 	 
	 	Per:	/s/ Anthony Giovinazzo
	 	 	Authorized Signing Officer
	 	 	 
	 	Per:	/s/ Andrew Williams
	 	 	Authorized Signing Officer

 

    	 	- 8 -

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