Document:

Exhibit 10.5

 

PLEDGE AGREEMENT

 

THIS PLEDGE AGREEMENT (this “Agreement”) is made as of July 6, 2017 by and between New England Realty Associates Limited Partnership, a Massachusetts limited partnership (“Pledgor”), and HBC Holdings, LLC, a Massachusetts limited liability company (“Pledgee”).

 

WHEREAS, Pledgor is the owner of 100% of the limited liability company interests (the “Pledged Interest”) in Woodland Park Partners, LLC, a Delaware limited liability company (the “Company”);

 

WHEREAS, Pledgor has entered into and accepted a loan (the “Loan”) from Pledgee in the amount of up to $16,000,000.00, which Loan is evidenced by a promissory note of even date herewith (the “Note”); and

 

WHEREAS, as collateral security for the payment of the Note, Pledgor desires to assign certain payments and the Pledged Interest to Pledgee.

 

NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Pledgor and Pledgee agree as follows:

 

1.                                      Pledge.

 

(a)                                 Pledgor hereby assigns to Pledgee as partial payments under the Note all periodic payments/distributions that Pledgor receives from the Company as the sole Member of the Company (the “Periodic Distributions”).  The Periodic Distributions shall be delivered to Pledgee by the Company and applied to the outstanding balance of the Note.

 

(b)                                 Pledgor hereby pledges, assigns and grants a security interest to Pledgee of 100% of the Pledged Interest as security for the full and faithful performance of all of the Obligations (as defined below).

 

(c)                                  Upon the occurrence of an Event of Default (as defined below), Pledgee shall have the rights and remedies provided under the Uniform Commercial Code in force in the Commonwealth of Massachusetts as of the date of this Pledge Agreement and, in connection therewith, Pledgee may, upon no less than ten (10) days’ written notice to Pledgor, sent by certified mail, return receipt requested, with all fees prepaid, sell any of the Pledged Interest in a commercially reasonable manner and for such price as Pledgee may determine in a commercially reasonable manner, subject to applicable law at a commercially reasonable public sale.  Pledgee shall be free to purchase all or any part of the Pledged Interest in Pledgee’s sole discretion.  To the extent of available sale proceeds, Pledgee may retain an amount equal to that owed to Pledgee by Pledgor pursuant to this Pledge Agreement, and any and all other instruments evidencing and securing the Obligations, plus the reasonable expenses of the sale, and shall promptly pay any balance of the sale proceeds, if any, to Pledgor.

 

 

(d)                                 Expenses of enforcing Pledgee’s rights hereunder including, but not limited to, preparation for sale, selling or the like and Pledgee’s reasonable attorneys’ fees and other expenses, shall be payable by Pledgor and shall be secured hereby.

 

(e)                                  All of the agreements, obligations, undertakings, representations and warranties herein made by Pledgor shall inure to the benefit of Pledgee and its respective successors and assigns, and shall bind Pledgor and his successors and assigns.

 

(f)                                   Pledgor agrees to execute any other instrument that Pledgee may deem necessary  or desirable to effectuate the purposes of this Pledge Agreement, in Pledgee’s reasonable discretion, including, without limitation, UCC financing and continuation statements.

 

2.                                      Obligations.  The Pledge hereby granted shall secure the following:

 

(a)                                 All Payments due under the Note;

 

(b)                                 the full and faithful performance, observance, fulfillment and compliance with all agreements, obligations and representations of Pledgor to the Pledgee, whether now existing or hereafter arising under this Agreement; and

 

(c)                                  all costs, expenses, losses, claims, damages, liabilities, penalties, suits, judgments or disbursements of any nature (including without limitation attorneys’ fees and disbursements) which may be incurred by, imposed on or asserted against Pledgee in connection with the exercise of any of Pledgee’s rights or remedies with respect to the Pledged Interest under this Pledge Agreement, or in connection with any enforcement, collection or other proceedings or any negotiations or other measure to pursue, interpret, enforce or exercise Pledgee’s rights or remedies hereunder.

 

The obligations set forth in this Section 2 are collectively referred to herein as the “Obligations.”

 

3.                                      Events of Default.   For purposes of this Pledge Agreement, the term “Event of Default” shall mean any of the following events or conditions:

 

(a)                                 Pledgor fails to pay the Note or to perform or observe any provision of this Agreement and such default is not remedied within ten (10) days after written notice of such default given to Pledgor by Pledgee.

 

4.                                      Waivers.    Pledgor hereby waives presentment, demand, notice, protest and, except as is otherwise provided herein, all other demands and notices in connection with this Pledge Agreement or the enforcement of the rights of Pledgee hereunder of in connection with any of the Obligations or the Pledged Interest; consents to and waives notice of the granting of renewals, extensions of time for payment or other indulgences to Pledgor or to any account debtor in respect of any account receivable or the substitution, release  or surrender of any portion of the Pledged Interest, the addition or release of persons primarily or secondarily liable on any Obligation or on any account receivable or other pledged interest, the acceptance of 

 

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partial payments on any Obligation or on any account receivable or other pledged interest and/or the settlement or compromise thereof.  No delay or omission on the part of Pledgee in exercising any right hereunder shall operate as a waiver of such right or of any other right hereunder.  Any waiver of any such right on any one occasion shall not be construed as a bar to or waiver of any such right on any such future occasion.  Pledgor further waives any right he may have to notice (other than any requirement of notice provided herein) prior to the exercise of any right or remedy provided by this Pledge Agreement to Pledgee and waives his rights, if any, to set aside or invalidate any sale duly consummated in accordance with the foregoing provisions hereof on the grounds (if such be the case) that the sale was consummated without a prior judicial hearing.  Pledgor’s waivers under this Section have been made voluntarily, intelligently knowingly and after Pledgor has been apprised and counseled by his attorneys as to the nature thereof and its possible alternative rights.

 

5.                                      Termination of Agreement.                                             This Pledge Agreement and the Pledge created herein shall terminate when the Loan has been paid and finally discharged in full.  No waiver by Pledgee or by any other holder of Obligations of any default shall be effective unless in writing, nor shall such waiver operate as a waiver of any other default or of the same default on a future occasion in the event of a sale or assignment by Pledgee of all or any of the Obligations held by Pledgee.

 

6.                                      Transfer/Assignment.                            Pledgor agrees that until this Pledge Agreement terminates, it shall not, without the express prior written consent of Pledgee, transfer, sell, pledge, exchange, or assign the Pledged Interest or any part thereof or interest therein or enter into any agreement for the transfer, sale, pledge or assignment of the Pledged Interest, or permit or suffer any other liens on the Pledged Interest, whether or not junior to the lien created hereby, to be created or to exist with respect to the Pledged Interest.

 

7.                                      Notices.   Except as otherwise provided herein, notice to Pledgor or to Pledgee shall be in writing and deemed to have been sufficiently given or served for all purposes hereof if delivered in hand by constable or other objective third party or mailed by first class certified or registered mail, return receipt requested, postage prepaid, at the respective addresses set forth in the opening paragraph hereof, or at such other address as the party to whom such notice is directed may have designated by like notice in writing to the other parties hereto.  A notice shall be deemed to have been given when delivered in hand or if mailed, on the earlier of (i) three (3) days after the date on which it is deposited in the mails, or (ii) the date on which it is received.

 

8.                                      Miscellaneous.  This Agreement shall inure to the benefit of and be binding upon the parties hereto and their respective successors and assigns, and the term “Pledgee” shall be deemed to include any other holder or holders of any of the Obligations.  In case a court of competent jurisdiction shall hold any provision in this Pledge Agreement to be invalid, illegal or unenforceable, the validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby.  This Agreement may be executed in any number of counterparts, each of which when so executed and delivered shall be an original, but all of which together shall constitute one instrument.

 

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9.                                      Governing Law; Jurisdiction.  This Agreement, including the validity hereof and the rights and obligations of the parties hereunder, shall be construed in accordance with and governed by the laws of the Commonwealth of Massachusetts.  Pledgor, to the extent that it may lawfully do so, hereby consents to the jurisdiction of the courts of the Commonwealth of Massachusetts and the United States District Court for the District of Massachusetts, as well as to the jurisdiction of all courts to which an appeal may be taken from such courts, for the purpose of any suit, action or other proceeding arising out of any of its obligations hereunder or with respect to the financing contemplated hereby, and expressly waives any and all objections it may have as to venue in any such courts.  Pledgor further agrees, to the extent that it may lawfully do so, that a summons and complaint commencing an action or proceeding in any of such courts shall be properly served and shall confer personal jurisdiction if served personally or by certified mail to it or him at the address provided in Section 9 of this Pledge Agreement or as otherwise provided under the laws of the Commonwealth of Massachusetts.

 

[PAGE ENDS HERE; SIGNATURE PAGE FOLLOWS]

 

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IN WITNESS WHEREOF, the undersigned have executed this Pledge Agreement as of the date first set forth above.

 

	
 
    	
PLEDGOR:
    
	
 
    	
 
    
	
 
    	
NEW   ENGLAND REALTY ASSOCIATES
    
	
 
    	
LIMITED   PARTNERSHIP, a Massachusetts
    
	
 
    	
limited   partnership
    
	
 
    	
 
    
	
 
    	
By:   NewReal, Inc., a Massachusetts corporation, its
    
	
 
    	
General   Partner
    
	
 
    	
 
    
	
 
    	
By:
    	
 
    
	
 
    	
 
    	
Ronald   Brown, President
    
	
 
    	
 
    
	
 
    	
 
    
	
 
    	
PLEDGEE:
    
	
 
    	
 
    
	
 
    	
HBC   HOLDINGS, LLC, a Massachusetts limited liability company
    
	
 
    
	
 
    	
 
    
	
 
    	
 
    
	
 
    	
By:
    	
 
    
	
 
    	
 
    	
Harold   Brown, Manager
    

 

5EX-10.16(B)

 Exhibit 10.16B 

SEPARATION AGREEMENT 

This Separation Agreement (the “Agreement”) by and between Casi DeYoung (“Executive”) and Mirna
Therapeutics, Inc., a Delaware corporation (the “Company”), is made effective eight (8) days after Executive’s signature hereto (the “Effective Date”), unless Executive revokes her acceptance of this
Agreement as provided in Section 5(c) below, with reference to the following facts: 
 A. Executive’s employment with the Company
and status as an officer and employee of the Company and each of its affiliates will end effective upon the Separation Date (as defined below). 

B. Executive and the Company want to end their relationship amicably and also to establish the obligations of the parties including, without
limitation, all amounts due and owing to Executive. 
 C. The payments and benefits being made available to Executive pursuant to this
Agreement are intended to satisfy all outstanding obligations under that certain Change in Control Severance Agreement by and between Executive and the Company (the “Severance Agreement”). 

NOW, THEREFORE, in consideration of the mutual covenants and agreements hereinafter set forth, the parties agree as follows: 

1. Separation Date. Executive acknowledges and agrees that her status as an officer and employee of the Company will end effective as of
June 30, 2017 (the “Separation Date”). Executive hereby agrees to execute such further document(s) as shall be determined by the Company as necessary or desirable to give effect to the end of Executive’s status as an
officer of the Company and, if applicable, officer and/or director of any of its subsidiaries; provided that such documents shall not be inconsistent with any of the terms of this Agreement. 

2. Final Paycheck; Payment of Accrued Wages and Expenses. 

(a) Final Paycheck. As soon as administratively practicable on or after the Separation Date, the Company will pay
Executive all accrued but unpaid base salary earned through the Separation Date, subject to standard payroll deductions and withholdings. Executive is entitled to these payments regardless of whether Executive executes this Agreement. 

(b) Business Expenses. The Company shall reimburse Executive for all outstanding expenses incurred prior to the
Separation Date which are consistent with the Company’s policies in effect from time to time with respect to travel, entertainment and other business expenses, subject to the Company’s requirements with respect to reporting and documenting
such expenses, including, without limitation, expenses incurred pursuant to Executive’s services as a director of any of the Company’s subsidiaries. 

3. Separation Payments and Benefits. Without admission of any liability, fact or claim, the Company hereby agrees, subject to this
Agreement becoming effective and irrevocable, as well as Executive’s performance of her continuing obligations pursuant to this Agreement and that certain Confidentiality, Covenant Not To Compete & Arbitration Agreement by and between
the Company and Executive dated March 1, 2014 (the “Confidentiality Agreement”) (including, without limitation, the non-competition and non-solicitation restrictive covenants set forth therein for the

  
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periods set forth in the Confidentiality Agreement), to provide Executive the severance benefits set forth below. Specifically, the Company and Executive agree as follows: 

(a) Severance. The Company shall pay to Executive four hundred eleven thousand and seventy five dollars ($411,075),
which represents the sum of (i) twelve (12) months of Executive’s annual base salary and (ii) one (1) times Executive’s target annual bonus assuming achievement of performance goals at target, in each case, at the rate
in effect immediately prior to the Separation Date, in a single cash lump sum. Such payment shall be made, less applicable withholdings and deductions, on or as soon as reasonably practicable following the first regularly scheduled payroll date
following the date this Agreement becomes effective and irrevocable. 
 (b) Healthcare Continuation Coverage. If
Executive elects to receive continued healthcare coverage pursuant to the provisions of the Consolidated Omnibus Budget Reconciliation Act of 1985, as amended (“COBRA”), the Company shall directly pay, or reimburse Executive for,
that portion of the premium for Executive and Executive’s covered dependents necessary such that Executive contributes the same amount to COBRA coverage as Executive contributed to medical, dental and vision coverage prior to the date of this
Agreement, such payment or reimbursement to continue until the earlier of (i) the last day of the twelfth (12th) full calendar month anniversary following the date this Agreement becomes
effective and irrevocable or (ii) the date Executive becomes eligible for comparable coverage under another employer’s plans. After the Company ceases to pay premiums pursuant to the preceding sentence, Executive may, if eligible, elect to
continue healthcare coverage at Executive’s expense in accordance with the provisions of COBRA. Executive acknowledges that she shall be solely responsible for all matters relating to Executive’s continuation of coverage pursuant to COBRA,
including, without limitation, Executive’s election of such coverage and her timely payment of premiums. 
 (c)
Equity Awards. Each outstanding and unvested equity award, including, without limitation, each stock option and restricted stock award, held by Executive (collectively, the “Equity Awards”) shall become vested and, if
applicable, exercisable and any forfeiture restrictions or rights of repurchase thereon shall immediately lapse, in each case, with respect to one hundred percent (100%) of that number of unvested shares underlying the Equity Awards as of the
Separation Date. The Equity Awards shall otherwise be subject to the terms of the applicable award agreements (the “Equity Award Agreements”) and the terms of the Agreement and Plan of Merger and Reorganization by and among the
Company, Meerkat Merger Sub, Inc., and Synlogic, Inc. (“Synlogic”), dated as of May 15, 2017 (the “Merger Agreement”), pursuant to which Synlogic will become a wholly-owned subsidiary of the Company (the
“Merger”). Executive acknowledges that pursuant to the Merger Agreement, (i) each of Executive’s stock options that is outstanding as of the effective time of the Merger that has an exercise price equal or greater than the
Meerkat Closing Price (as defined in the Merger Agreement) will be terminated for no consideration and (ii) Executive’s other stock options that are outstanding as of the effective time of the Merger will be automatically exercised in
full, and Executive will be entitled to receive a number of shares of Company common stock determined in accordance with the Merger Agreement. 

(d) Taxes. Executive understands and agrees that all payments under this Section 3 will be subject to appropriate
tax withholding and other deductions. To the extent any taxes may be payable by Executive for the benefits provided to her by this Section 3 beyond those withheld by the Company, Executive agrees to pay them herself and to

  
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indemnify and hold the Company and the other entities released herein harmless for any tax claims or penalties, and associated attorneys’ fees and costs, resulting from any failure by her to
make required payments. To the extent that any reimbursements payable pursuant to this Agreement are subject to the provisions of Section 409A of the Internal Revenue Code of 1986, as amended (the “Code”), such reimbursements
shall be paid to Executive no later than December 31 of the year following the year in which the expense was incurred, the amount of expenses reimbursed in one year shall not affect the amount eligible for reimbursement in any subsequent year,
and Executive’s right to reimbursement under this Agreement will not be subject to liquidation or exchange for another benefit. 

(e) SEC Reporting. Executive acknowledges that to the extent required by the Securities Exchange Act of 1934, as amended
(the “Exchange Act”), she will have continuing obligations under Section 16(a) and 16(b) of the Exchange Act to report Executive’s matching transactions in Company common stock for six (6) months following the
Separation Date. Executive hereby agrees not to undertake, directly or indirectly, any reportable transactions involving the common stock of the Company until the end of such six (6) month period. 

(f) Sole Separation Benefit. Executive agrees that the payments provided by this Section 3 are not required under
the Company’s normal policies and procedures and are provided as a severance solely in connection with this Agreement. Executive acknowledges and agrees that the payments referenced in this Section 3 constitute adequate and valuable
consideration, in and of themselves, for the promises contained in this Agreement. 
 4. Full Payment. Executive acknowledges that the
payment and arrangements herein shall constitute full and complete satisfaction of any and all amounts properly due and owing to Executive as a result of her employment with the Company and the termination thereof. Executive further acknowledges
that, other than the Equity Award Agreements, the Confidentiality Agreement and the Indemnification Agreement between Executive and the Company (the “Indemnification Agreement”), this Agreement shall supersede each agreement entered
into between Executive and the Company regarding Executive’s employment, including, without limitation, any offer letter, the Severance Agreement and that certain employment agreement by and between Executive and the Company dated
October 23, 2015, and each such agreement shall be deemed terminated and of no further effect as of the Separation Date. 
 5.
Executive’s Release of the Company. Executive understands that by agreeing to the release provided by this Section 5, Executive is agreeing not to sue, or otherwise file any claim against, the Company or any of its employees or
other agents for any reason whatsoever based on anything that has occurred as of the date Executive signs this Agreement. 

(a) On behalf of Executive and Executive’s heirs, assigns, executors, administrators, trusts, spouse and estate, Executive
hereby releases and forever discharges the “Releasees” hereunder, consisting of the Company, and each of its owners, affiliates, subsidiaries, predecessors, successors, assigns, agents, directors, officers, partners, employees, and
insurers, and all persons acting by, through, under or in concert with them, or any of them, of and from any and all manner of action or actions, cause or causes of action, in law or in equity, suits, debts, liens, contracts, agreements, promises,
liability, claims, demands, damages, loss, cost or expense, of any nature whatsoever, known or unknown, fixed or contingent (hereinafter called “Claims”), which Executive now has or may hereafter have against the Releasees, or any
of them, by reason of any matter, cause, or thing 

  
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whatsoever from the beginning of time to the date hereof, including, without limiting the generality of the foregoing, any Claims arising out of, based upon, or relating to Executive’s hire,
employment, remuneration or resignation by the Releasees, or any of them, Claims arising under federal, state, or local laws relating to employment, Claims of any kind that may be brought in any court or administrative agency, including any Claims
arising under the Age Discrimination in Employment Act (“ADEA”), 29 U.S.C. § 621, et seq.; Title VII of the Civil Rights Act of 1964, as amended by the Civil Rights Act of 1991, 42 U.S.C. § 2000 et seq.;
the Equal Pay Act, 29 U.S.C. § 206(d); the Civil Rights Act of 1866, 42 U.S.C. § 1981; the Family and Medical Leave Act of 1993, 29 U.S.C. § 2601 et seq.; the Americans with Disabilities Act of 1990, 42 U.S.C. § 12101
et seq.; the False Claims Act , 31 U.S.C. § 3729 et seq.; the Employee Retirement Income Security Act, 29 U.S.C. § 1001 et seq.; the Worker Adjustment and Retraining Notification Act, 29 U.S.C. § 2101 et
seq. the Fair Labor Standards Act, 29 U.S.C. § 215 et seq., the Sarbanes-Oxley Act of 2002; the Texas Labor Code, including the Texas Commission on Human Rights Act; Section 451.001 of the Texas Workers’ Compensation Act;
the Texas Payday Act; and the Texas Labor Code; Claims for breach of contract; Claims arising in tort, including, without limitation, Claims of wrongful dismissal or discharge, discrimination, harassment, retaliation, fraud, misrepresentation,
defamation, libel, infliction of emotional distress, violation of public policy, and/or breach of the implied covenant of good faith and fair dealing; and Claims for damages or other remedies of any sort, including, without limitation, compensatory
damages, punitive damages, injunctive relief and attorney’s fees. 
 (b) Notwithstanding the generality of the
foregoing, Executive does not release the following claims: 
 (i) Claims for unemployment compensation or any state
disability insurance benefits pursuant to the terms of applicable state law; 
 (ii) Claims for workers’ compensation
insurance benefits under the terms of any worker’s compensation insurance policy or fund of the Company; 
 (iii) Claims
to continued participation in certain of the Company’s group benefit plans pursuant to the terms and conditions of COBRA; 

(iv) Claims to any benefit entitlements vested as the date of Executive’s employment termination, pursuant to written
terms of any Company employee benefit plan; 
 (v) Claims for indemnification under the Indemnification Agreement, the
Company’s Bylaws or any applicable law; and 
 (vi) Executive’s right to bring to the attention of the Equal
Employment Opportunity Commission claims of discrimination; provided, however, that Executive does release Executive’s right to secure any damages for alleged discriminatory treatment. 

(c) In accordance with the Older Workers Benefit Protection Act of 1990, Executive has been advised of the following: Executive
acknowledges that Executive is knowingly and voluntarily waiving and releasing any rights Executive may have under the ADEA. Executive also acknowledges that the consideration given for the waiver and release herein is in addition to anything of
value to which Executive was already entitled. Executive 

  
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further acknowledges that Executive has been advised by this writing, as required by the ADEA, that: (i) Executive’s waiver and release do not apply to any rights or claims that may
arise after the execution date of this Agreement; (ii) Executive has been advised hereby that Executive has the right to consult with an attorney prior to executing this Agreement; (iii) Executive has forty-five (45) days from the
date of this Agreement to execute this Agreement (although Executive may choose to voluntarily execute this Agreement earlier); (iv) Executive has received with this Agreement a detailed list of the job titles and ages of all employees who were
terminated in this group termination and the ages of all employees of the Company in the same job classification or organizational unit who were not terminated, attached hereto as Appendix A; (v) Executive has seven (7) days following the
execution of this Agreement by Executive to revoke the Agreement, and Executive will not receive the severance benefits provided by Section 3 of this Agreement unless and until such seven (7) day period has expired; (vi) this
Agreement will not be effective until the date upon which the revocation period has expired, which will be the eighth (8th) day after this Agreement is executed by Executive, provided
that the Company has also executed this Agreement by that date; and (vii) this Agreement does not affect Executive’s ability to test the knowing and voluntary nature of this Agreement. If Executive wishes to revoke this Agreement,
Executive must deliver notice of Executive’s revocation in writing, no later than 5:00 p.m. Central Time on the 7th day following Executive’s execution of this Agreement to Alan Fuhrman, P.O Box 163387, Austin, TX 78716, or e-mail:
afuhrman@mirnarx.com. 
 6. Non-Disparagement, Transition, Transfer of Company Property and Limitations on Service. Both parties
further agree that: 
 (a) Non-Disparagement. Both parties agree that they shall not disparage, criticize or defame
the other party and their respective directors, officers, agents, partners, stockholders, employees, products, services, technology or business, either publicly or privately. Nothing in this Section 6(a) shall have application to any evidence
or testimony required by any court, arbitrator or government agency. 
 (b) Transition. Each of the Company and
Executive shall use their respective reasonable efforts to cooperate with each other in good faith to facilitate a smooth transition of Executive’s duties to other executive(s) of the Company. 

(c) Transfer of Company Property. On or before the Separation Date, Executive shall turn over to the Company all files,
memoranda, records, and other documents, and any other physical or personal property which are the property of the Company and which she had in her possession, custody or control at the time she signed this Agreement. 

7. Executive Representations. Executive warrants and represents that (a) she has not filed or authorized the filing of any
complaints, charges or lawsuits against the Company or any affiliate of the Company with any governmental agency or court, and that if, unbeknownst to Executive, such a complaint, charge or lawsuit has been filed on her behalf, she will immediately
cause it to be withdrawn and dismissed, (b) she has reported all hours worked as of the date of this Agreement and has been paid all compensation, wages, bonuses, commissions, and/or benefits to which she may be entitled and no other
compensation, wages, bonuses, commissions and/or benefits are due to her, except as provided in this Agreement, (c) she has no known workplace injuries or occupational diseases and has been provided and/or has not been denied any leave
requested under the Family and Medical Leave Act or any similar state law, (d) the execution, delivery and performance of this Agreement by Executive does not and will not conflict with, breach, violate or cause a default

  
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under any agreement, contract or instrument to which Executive is a party or any judgment, order or decree to which Executive is subject, and (e) upon the execution and delivery of this
Agreement by the Company and Executive, this Agreement will be a valid and binding obligation of Executive, enforceable in accordance with its terms. 

8. No Assignment by Executive. Executive warrants and represents that no portion of any of the matters released herein, and no portion
of any recovery or settlement to which Executive might be entitled, has been assigned or transferred to another person, firm or corporation not a party to this Agreement, in any manner, including by way of subrogation or operation of law or
otherwise. If any claim, action, demand or suit should be made or instituted against the Company or any other Releasee because of any actual assignment, subrogation or transfer by Executive, Executive agrees to indemnify and hold harmless the
Company and all other Releasees against such claim, action, suit or demand, including necessary expenses of investigation, attorneys’ fees and costs. In the event of Executive’s death, this Agreement shall inure to the benefit of Executive
and Executive’s executors, administrators, heirs, distributees, devisees, and legatees. None of Executive’s rights or obligations may be assigned or transferred by Executive, other than Executive’s rights to payments hereunder, which
may be transferred only upon Executive’s death by will or operation of law. 
 9. Governing Law. This Agreement shall be
construed and enforced in accordance with, and the rights of the parties shall be governed by, the laws of the State of Texas or, where applicable, United States federal law, in each case, without regard to any conflicts of laws provisions or those
of any state other than Texas. 
 10. Miscellaneous. This Agreement, collectively with the Confidentiality Agreement, the
Indemnification Agreement and the Equity Award Agreements, comprise the entire agreement between the parties with regard to the subject matter hereof and supersedes, in their entirety, any other agreements between Executive and the Company with
regard to the subject matter hereof. The Company and Executive acknowledge that the separation of the Executive’s employment with the Company is intended to constitute an involuntary separation from service for the purposes of Section 409A
of the Code, and the related Department of Treasury regulations. Executive acknowledges that there are no other agreements, written, oral or implied, and that she may not rely on any prior negotiations, discussions, representations or agreements.
This Agreement may be modified only in writing, and such writing must be signed by both parties and recited that it is intended to modify this Agreement. This Agreement may be executed in separate counterparts, each of which is deemed to be an
original and all of which taken together constitute one and the same agreement. 
 11. Company Assignment and Successors. The Company
shall assign its rights and obligations under this Agreement to any successor to all or substantially all of the business or the assets of the Company (by merger or otherwise). This Agreement shall be binding upon and inure to the benefit of the
Company and its successors, assigns, personnel and legal representatives. 
 12. Maintaining Confidential Information. Executive
reaffirms her obligations under the Confidentiality Agreement. Executive acknowledges and agrees that the payments provided in Section 3 above shall be subject to Executive’s continued compliance with Executive’s obligations under the
Confidentiality Agreement. For the avoidance of doubt, nothing in this Agreement will be construed to prohibit Executive from filing a charge with, reporting possible violations to, or participating or cooperating with any governmental agency or
entity, including but not limited to the EEOC, the Department of Justice, the Securities and Exchange Commission, Congress, or any agency Inspector General, or making other disclosures that are protected under the whistleblower, anti-discrimination,
or anti-retaliation provisions of federal, state or local law or regulation; provided, however, that Executive may not disclose information of the Company that is protected by the 

  
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attorney-client privilege, except as otherwise required by law. Executive does not need the prior authorization of the Company to make any such reports or disclosures, and Employee is not
required to notify the Company that Executive has made such reports or disclosures. 
 13. Executive’s Cooperation. After
the Separation Date, Executive shall cooperate with the Company and its affiliates, upon the Company’s reasonable request, with respect to any internal investigation or administrative, regulatory or judicial proceeding involving matters within
the scope of Executive’s duties and responsibilities to the Company or its affiliates during her employment with the Company (including, without limitation, Executive being available to the Company upon reasonable notice for interviews and
factual investigations, appearing at the Company’s reasonable request to give testimony without requiring service of a subpoena or other legal process, and turning over to the Company all relevant Company documents which are or may have come
into Executive’s possession during her employment); provided, however, that any such request by the Company shall not be unduly burdensome or interfere with Executive’s personal schedule or ability to engage in gainful
employment.
 (Signature page(s) follow) 

  
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 IN WITNESS WHEREOF, the undersigned have caused this Separation Agreement to be duly executed and
delivered as of the date indicated next to their respective signatures below. 
 DATED: June 29, 2017 

 

							
		 		 	/s/ Casi DeYoung
		 		 	Casi De Young
		 		 	
			
		 		 	MIRNA THERAPEUTICS, INC.
	DATED: June 29, 2017	 		 	
				
		 		 	By:	 	/s/ Paul Lammers
		 		 		 	Paul Lammers
		 		 		 	President and CEO

  
 S-1 

 APPENDIX A 

DEMOGRAPHIC NOTICE 
  

									
	 NAME
	  	 TITLE
	  	DATE OF
BIRTH	  	JOB
ELIMINATED	  	ELIGIBLE FOR
SEPARATION
BENEFITS
	 Vincent O’Neill
	  	Chief Medical Officer	  	[###]	  	Yes	  	Yes
	 John Stoudemire
	  	VP – Preclinical Development	  	[###]	  	Yes	  	Yes
	 Casi De Young
	  	Chief Business Officer	  	[###]	  	Yes	  	Yes

  
 A-1

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00272-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00272-of-00352.parquet"}]]