Document:

Exhibit
10.9

 

EMPLOYMENT
AGREEMENT

 

This
Employment Agreement (“Agreement”) is effective as of July 1, 2014 (“Effective Date”), by and between
Bacterin International, Inc., a Nevada corporation (the “Company”), and Robert Di Silvio, an individual
(“Employee”).

 

In
consideration of the mutual promises, covenants and agreements contained in this Agreement, and other good and valuable
consideration, the receipt and sufficiency of which is hereby acknowledged, the Parties agree as follows:

 

1.                EMPLOYMENT
AND DUTIES.

 

A.           Job
Title and Responsibilities.
The Company hereby employs Employee, and Employee hereby agrees to be employed, as President reporting to the Chief Executive
Officer. Employee’s title and responsibilities may change during the course of Employee’s employment with Employer,
but the terms of this Agreement shall remain in full force and effect regardless of any change in Employee’s title or responsibilities.

 

B.           Full-Time
Best Efforts. Employee agrees to devote
Employee’s full professional time and attention to the business of the Company (and
its subsidiaries, affiliates, or related entities) and the performance of Employee’s obligations under this Agreement, and
will at all times faithfully, industriously and to the best of Employee’s ability, experience and talent, perform all of Employee’s
obligations hereunder. Employee shall not, at any time during Employee’s employment by the Company, directly or indirectly, act
as a partner, officer, director, consultant, employee, or provide services in any other capacity to any other business enterprise
that conflicts with the Company’s business or Employee’s duty of loyalty to the Company. Without limiting the generality
of the foregoing, Employee has disclosed that he currently serves on the board of directors of two companies. Employee shall seek
the written consent of the Company prior to accepting any further outside board positions or prior to materially expanding his
role on the current boards on which he serves.

 

C.           Duty
of Loyalty. Employee
acknowledges that during Employee’s employment with the Company, Employee has participated in and will participate in relationships
with existing and prospective clients, customers, partners, suppliers, service providers and vendors of the Company that are essential
elements of the Company’s goodwill. The parties acknowledge that Employee owes the Company a fiduciary duty to conduct all
affairs of the Company in accordance with all applicable laws and the highest standards of good faith, trust, confidence and candor,
and to endeavor, to the best of Employee’s ability, to promote the best interests of the Company.

 

D.           Conflict
of Interest. Employee agrees that while employed by the Company, and except with
the advance written consent of a duly authorized officer of the Company, Employee will not enter into, on behalf of the Company,
or cause the Company or any of its affiliates to enter into, directly or indirectly, any transactions with any business organization
in which Employee or any member of Employee’s immediate family may be interested as a shareholder, partner, member, trustee,
director, officer, employee, consultant, lender or guarantor or otherwise; provided, however, that nothing in this Agreement shall
restrict transactions between the Company and any company whose stock is listed on a national securities exchange or actively
traded in the over-the-counter market and over which Employee does not have the ability to control or significantly influence
policy decisions.

 

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2.                
COMPENSATION.

 

A.           Base
Pay. The Company agrees to pay Employee gross annual compensation of $325,000, less usual and customary withholdings, which
shall be payable in arrears in accordance with the Company’s customary payroll practices.

 

B.           Bonus
and Incentive Compensation. Employee shall also be eligible for bonus and incentive based compensation approved by the Compensation
Committee of the Board of Directors from time to time. The target bonus compensation will be 50% of base pay. Such bonus and incentive
compensation shall be paid in accordance with the bonus and incentive compensation plan documents adopted by the Company, or in
the absence of such plan documents, no later than 2-1/2 months following the year in which the bonus or incentive compensation
vests.

 

C.           Stock
Option. Subject to the approval of the Compensation Committee of the Company’s Board of Directors, the Company will cause
Bacterin International Holdings, Inc. (“BONE”) to grant Employee an option to purchase 550,000 shares of BONE common
stock at an exercise price equal to the closing price of BONE common stock on the second trading day following the Company’s
second quarter earnings release (the “Option”). The Option will vest as follows:(i) twenty percent (20%), or 110,000
underlying shares, will vest on the first anniversary of the date of grant, and (ii) the remaining eighty percent (80%) will vest
in forty- seven (47) equal monthly installments as to 9,170 underlying shares, beginning one month after the first anniversary
of the date of grant, and one final installment as to 9,010 underlying shares. Employee must remain employed by the Company for
vesting to occur. Upon a Change in Control as defined in the Company’s Amended and Restated Equity Incentive Plan, the entire
Option shall immediately be 100% vested without regard to the schedule contained in the Option agreement and the entire Option
shall become immediately exercisable in full during its remaining term.

 

D.           Benefits.
During Employee’s employment, Employee will be eligible to participate in the Company’s benefit programs, as summarized
and as governed by any plan documents concerning such benefits. Employee will be eligible for three weeks of paid vacation per
year, subject to the Company’s carryover policy.

 

3.                PROPRIETARY
INFORMATION.

 

A.           Employee
understands that during Employee’s employment relationship with the Company, the Company intends to provide Employee with
information, including Proprietary Information (as defined herein), without which Employee would not be able to perform Employee’s
duties to the Company. Employee agrees, at all times during the term of Employee’s employment relationship and thereafter, to hold
in strictest confidence, and not to use or disclose, except for the benefit of the Company to the extent necessary to perform Employee’s
obligations to the Company, any Proprietary Information that Employee obtains, accesses or creates during the term of the relationship,
whether or not during working hours, until such Proprietary Information becomes publicly and widely known and made generally available
through no wrongful act of Employee or of others under confidentiality obligations as to the information involved. Employee understands
that “Proprietary Information” means information and physical material not generally known or available outside the Company
and information and physical material entrusted to the Company by third parties under an obligation of non-disclosure or non-use
or both. “Proprietary Information” includes, without limitation, inventions, technical data, trade secrets, marketing
ideas or plans, research, product or service ideas or plans, business strategies, investments, investment opportunities, potential
investments, market studies, industry studies, historical financial data, financial information and results, budgets, identity
of customers, forecasts (financial or otherwise), possible or pending transactions, customer lists and domain names, price lists,
and pricing methodologies.

 

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B.           At
all times, both during Employee’s employment and after its termination, Employee will keep and hold all such Proprietary
Information in strict confidence and trust. Employee will not use or disclose any Proprietary Information without the prior written
consent of the Company, except as may be necessary to perform Employee’s duties as an employee of the Company for the benefit
of the Company. Employee may disclose information that Employee is required to disclose by valid order of a government agency or
court of competent jurisdiction, provided that Employee will:

 

	 	(i)	notify the Company in writing immediately upon learning that such an order may be sought or issued,

	 	(ii)	cooperate with the Company as reasonably requested if the Company seeks to contest such order or to place protective restrictions on the disclosure pursuant to such order, and

	 	(iii)	comply with any protective restrictions in such order, and disclose only the information specified in the order.

 

C.           Upon
termination of employment with the Company, Employee will promptly deliver to the Company all documents and materials of any nature
pertaining to Employee’s work with the Company.

 

D.           Employee
agrees not to infringe the copyright of the Company, its customers or third parties (including, without limitation, Employee’s
previous employer, customers, etc.) by unauthorized or unlawful copying, modifying or distributing of copyrighted material, including
plans, drawings, reports, financial analyses, market studies, computer software and the like.

 

4.                COVENANT
NOT TO COMPETE.

 

A.           Noncompetition
Covenant. Employee agrees that during the Restricted Period (as defined below), without the prior written consent of the Company,
Employee shall not, directly or indirectly within the Territory (as defined below): (i) personally, by agency, as an employee,
independent contractor, consultant, officer, director, manager, agent, associate, investor (other than as a passive investor holding
less than five percent of the outstanding equity of an entity), or by any other artifice or device, engage in any Competitive Business
(as defined below), (ii) assist others, including but not limited to employees of the Company, to engage in any Competitive Business,
or (iii) own, purchase, finance, organize or take preparatory steps to own, purchase, finance, or organize a Competitive Business.

 

B.           Definitions.

 

1.          “Competitive
Business” means (i) any person, entity or organization which is engaged in or about to become engaged in research on, consulting
regarding, or development, production, marketing or selling of any product, process, technology, device, invention or service which
resembles, competes with or is intended to resemble or compete with a product, process, technology, device, invention or service
of the Company; or (ii) any other line of business that was conducted by the Company or that Employee knows or reasonably should
know the Company or any affiliate, successor or related entity, at any time during the term of Employee’s employment with
the Company, is actively preparing to pursue.

 

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2.          “Territory”
means the United States of America.

 

3.          “Restricted
Period” means the period of Employee’s employment with the Company and for
a period of six (6) months following the termination of Employee’s employment; provided that if such termination is of
a type that results in severance under Paragraph 12B (or would result in severance if Employee had been employed for twelve
(12) full months), the Restricted Period after termination shall be the period of severance, if any, following such
termination.

 

5.                NON-SOLICITATION
AND NON-INTERFERENCE COVENANTS.

 

A.           Nonsolicitation
ofEmployeesand Others. During
the Restricted Period, (a) Employee shall not, directly or indirectly, solicit,
recruit, or induce, or attempt to solicit, recruit or induce any employee, consultant, independent contractor, vendor,
supplier, or agent to terminate or otherwise adversely affect his or her employment or other business relationship (or
prospective employment or business relationship) with the Company, and (b) Employee shall not, directly or indirectly,
solicit, recruit, or induce, or attempt to solicit, recruit or induce any employee to work for Employee or any other person
or entity, other than the Company or its affiliates or related entities.

 

B.           Nonsolicitation
ofCustomers.         During
the Restricted Period, Employee shall not, directly or indirectly, solicit,
recruit, or induce any Customer (as defined below) for the purpose of (i) providing any goods or services related to a
Competitive Business, or (ii) interfering with or otherwise adversely affecting the contracts or relationships, or
prospective contracts or relationships, between the Company (including any related or affiliated entities) and such
Customers. “Customer” means a person or entity with which Employee had contact or about whom Employee gained
information while an Employee of the Company, and to which the Company was selling or providing products or services, was in
active negotiations for the sale of its products or services, or was otherwise doing business as of the date of the cessation
of Employee’s employment with the Company or for whom the Company had otherwise done business within the twelve (12)
month period immediately preceding the cessation of Employee’s employment with the Company.

 

6.                 ACKNOWLEDGEMENTS.
Employee acknowledges and agrees that;

 

A.           The
geographic and duration restrictions contained in Paragraphs 4 and 5 of this Agreement are fair, reasonable, and necessary
to protect the Company’s legitimate business interests and trade secrets, given the geographic scope of the Company’s
business operations, the competitive nature of the Company’s business, and the nature of Employee’s position with the Company;

 

B.           Employee’s
employment creates a relationship of confidence and trust between Employee and the Company with respect to the Proprietary Information,
and Employee will have access to Proprietary Information (including but not limited to trade secrets) that would be valuable or
useful to the Company’s competitors;

 

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C.           The
Company’s Proprietary Information is a valuable asset of the Company, and any violation of the restrictions set forth in
this Agreement would cause substantial injury to the Company;

 

D.           The
restrictions contained in this Agreement will not unreasonably impair or infringe upon Employee’s right to work or earn a
living after Employee’s employment with the Company ends; and

 

E.           This
Agreement is a contract for the protection of trade secrets under applicable
lawand is intended to protect the Proprietary Information (including trade secrets)

identified
above.

 

7.                “BLUE
PENCIL” AND SEVERABILITY PROVISION. If a court of competent
jurisdiction declares any provision of this Agreement invalid, void, voidable, or unenforceable, the court shall reform such provision(s)
to render the provision(s) enforceable, but only to the extent absolutely necessary to render the provision(s) enforceable and
only in view of the Parties’ express desire that the Company be protected to the greatest possible extent under applicable law
from improper competition and the misuse or disclosure of trade secrets and Proprietary Information. To the extent such a provision
(or portion thereof) may not be reformed so as to make it enforceable, it may be severed and the remaining provisions shall remain
fully enforceable.

 

8.                 INVENTIONS.

 

A.           Inventions
Retained and Licensed. Attached as Exhibit
A is a list describing all inventions and information created, discovered or developed by Employee, whether or not patentable
or registrable under patent, copyright or similar statutes, made or conceived or reduced to practice or learned by Employee, either
alone or with others before Employee’s employment with the Company (“Prior Inventions”), which belong in whole
or in part to Employee, and which are not being assigned by Employee to the Company. Employee represents that Exhibit A is complete
and contains no confidential or proprietary information belonging to a person or entity other than Employee. Employee acknowledges
and agrees that Employee has no rights in any Inventions (as that term is defined below) other than the Prior Inventions listed
on Exhibit A. If there is nothing identified on Exhibit A, Employee represents that there are no Prior Inventions as of the time
of signing this Agreement. Employee shall not incorporate, or permit to be incorporated, any Prior Invention owned by Employee
or in which he/she has an interest in a Company product, process or machine without the Company’s prior written consent. Notwithstanding
the foregoing, if, in the course of Employee’s employment with the Company, Employee directly or indirectly incorporates
into a Company product, process or machine a Prior Invention owned by Employee or in which Employee has an interest, the Company
is hereby granted and shall have a non-exclusive, royalty-free, irrevocable, perpetual, world-wide license to make, have made,
modify, use, create derivative works from and sell such Prior Invention as part of or in connection with such product, process
or machine.

 

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B.           Assignment
Of Inventions. Employee shall promptly make
full, written disclosure to the Company, will hold in trust for the sole right and benefit of the Company, and hereby irrevocably
transfers and assigns, and agrees to transfer and assign, to the Company, or its designee, all his/her right, title and interest
in and to any and all inventions, original works of authorship, developments, concepts, improvements, designs, discoveries, ideas,
trademarks (and all associated goodwill), mask works, or trade secrets, whether or not they may be patented or registered under
copyright or similar laws, which Employee may solely or jointly conceive or develop or reduce to
practice, or cause to be conceived or developed or reduced to practice, during Employee’s employment by the Company (the
“Inventions”). Employee further acknowledges that all original works of authorship which are made by Employee (solely
or jointly with others) within the scope of and during the period of his/her employment with the Company and which may be protected
by copyright are “Works Made For Hire” as that term is defined by the United States Copyright Act. Employee understands
and agrees that the decision whether to commercialize or market any Invention developed by Employee solely or jointly with others
is within the Company’s sole discretion and the Company’s sole benefit and that no royalty will be due to Employee as a result
of the Company’s efforts to commercialize or market any such invention.

 

Employee
recognizes that Inventions relating to his or her activities while working for the Company and conceived or made by Employee, whether
alone or with others, within one (1) year after cessation of Employee’s employment, may have been conceived in significant
part while employed by the Company. Accordingly, Employee acknowledges and agrees that such Inventions shall be presumed to have
been conceived during Employee’s employment with the Company and are to be, and hereby are, assigned to the Company unless and
until Employee has established the contrary.

 

C.           Maintenance
of Records. Employee agrees to keep and maintain
adequate and current written records of all Inventions made by Employee (solely or jointly with others) during his/her employment
with the Company. The records will be in the form of notes, sketches, drawings and any other format that may be specified by the
Company. The records will be available to and remain the sole property of the Company at all times.

 

D.           Patent,
Trademark and Copyright Registrations. Employee
agrees to assist the Company, or its designee, at the Company’s expense, in every proper way to secure the Company’s rights in
the Inventions and any copyrights, patents, trademarks, service marks, mask works, or any other intellectual property rights in
any and all countries relating thereto, including, but not limited to, the disclosure to the Company of all pertinent information
and data with respect thereto, the execution of all applications, specifications, oaths, assignments and all other instruments
the Company reasonably deems necessary in order to apply for and obtain such rights and in order to assign and convey to the Company,
its successors, assigns, and nominees the sole and exclusive rights, title, and interest in and to such inventions, and any copyrights,
patents, trademarks, service marks, mask works, or any other intellectual property rights relating thereto. Employee further agrees
that his/her obligation to execute or cause to be executed, when it is in his/her power to do so, any such instrument or paper
shall continue after termination or expiration of this Agreement or the cessation of his/her employment with the Company. If the
Company is unable because of Employee’s mental or physical incapacity or for any other reason, after reasonably diligent efforts,
to secure Employee’s signature to apply for or to pursue any application for any United States or foreign patents, trademarks or
copyright registrations covering inventions or original works of authorship assigned to the Company as above, then Employee hereby
irrevocably designates and appoints the Company and its duly authorized officers and agents as Employee’s agent and attorney-in-fact
to act for and in his/her behalf and stead to execute and file any such applications and to do all other lawfully permitted acts
to further the prosecution and issuance of letters patent, trademarks or copyright registrations thereon with the same legal force
and effect as if executed by Employee; this power of attorney shall be a durable power of attorney which shall come into existence
upon Employee’s mental or physical incapacity.

 

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9.                 SURVIVAL
AND REMEDIES. Employee’s obligations of nondisclosure, nonsolicitation,
noninterference, and noncompetition under this Agreement shall survive the cessation of Employee’s employment with the Company
and shall remain enforceable. In addition, Employee acknowledges that upon a breach or threatened breach of any obligation of
nondisclosure, nonsolicitation, noninterference, or noncompetition of this Agreement, the Company may suffer irreparable harm
and damage for which money alone cannot fully compensate the Company. Employee therefore agrees that upon such breach or threat
of imminent breach of any such obligation, the Company shall be entitled to seek a temporary restraining order, preliminary injunction,
permanent injunction or other injunctive relief, without posting any bond or other security, barring Employee from violating any
such provision. This Paragraph shall not be construed as an election of any remedy, or as a waiver of any right available to the
Company under this Agreement or the law, including the right to seek damages from Employee for a breach of any provision of this
Agreement and the right to require Employee to account for and pay over to the Company all profits or other benefits derived or
received by Employee as the result of such a breach, nor shall this Paragraph be construed to limit the rights or remedies available
under state law for any violation of any provision of this Agreement.

 

10.              RETURN
OF COMPANY PROPERTY. All devices, records, reports, data,
notes, compilations, lists, proposals, correspondence, specifications, equipment, drawings, blueprints, manuals, DayTimers, planners,
calendars, schedules, discs, data tapes, financial plans and information, or other recorded matter, whether in hard copy, magnetic
media or otherwise (including all copies or reproductions made or maintained, whether on the Company’s premises or otherwise),
pertaining to Employee’s work for the Company, or relating to the Company or the Company’s Proprietary Information, whether
created or developed by Employee alone or jointly during his/her employment with the Company, are the exclusive property of the
Company. Employee shall surrender the same (as well as any other property of the Company) to the Company upon its request or promptly
upon the cessation of employment. Upon cessation of Employee’s employment, Employee agrees to sign and deliver the “Termination
Certificate” attached as Exhibit B, which shall detail all Company property that is surrendered upon cessation of employment

 

11.              NO
CONFLICTING AGREEMENTS OR IMPROPER USE OF THIRD-PARTY INFORMATION.
During her/his employment with the Company, Employee shall not improperly use or disclose any proprietary information or trade
secrets of any former employer or other person or entity, and Employee shall not bring on to the premises of the Company any unpublished
document or proprietary information belonging to any such former employer, person or entity, unless consented to in writing by
the former employer, person or entity. Employee represents that he/she has not improperly used or disclosed any proprietary information
or trade secrets of any other person or entity during the application process or while employed or affiliated with the Company.
Employee also acknowledges and agrees that he/she is not subject to any contract, agreement, or understanding that would prevent
Employee from performing his/her duties for the Company or otherwise complying with this Agreement. To the extent Employee violates
this provision, or his/her employment with the Company constitutes a breach or threatened breach of any contract, agreement, or
obligation to any third party, Employee shall indemnify and hold the Company harmless from all damages, expenses, costs (including
reasonable attorneys’ fees) and liabilities incurred in connection with, or resulting from, any such violation or threatened
violation.

 

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12.              TERMINATION.

 

A.           By
Either Party. Either Party may terminate this Agreement at any time with or without notice, and with or without cause. Except
as provided in this Paragraph 12, upon termination of employment, Employee shall only be entitled to Employee’s accrued but
unpaid base salary and other benefits earned under any Company-provided plans, policies and arrangements for the period preceding
the effective date of the termination of employment.

  

B.           Termination
Without Cause or Resignation for Good Reason. If the Company terminates Employee’s employment without Cause (defined
below) or Employee resigns for Good Reason (defined below), Employee shall be entitled to receive continuing bi-weekly payments
of severance pay at a rate equal to Employee’s Base Salary, as then in effect, for six (6) months from the date of termination
of employment, less all required tax withholdings and other applicable deductions, payable in accordance with the Company’s
standard payroll procedures, commencing on the effective date of a separation agreement with a complete release of claims against
the Company; provided that (1) the first payment shall include any amounts that would have been paid to Employee if payment had
commenced on the date of separation from service; (2) Employee shall not be required to execute a release of any claims arising
from the Company’s failure to comply with its obligations under Paragraph 12A above; and (3) notwithstanding the preceding
provisions of this Paragraph 12B, no severance shall be due or payable unless and until Employee has been employed with the Company
for at least twelve (12) full months. Notwithstanding the foregoing, any payments due under this Paragraph 12B shall commence within
sixty (60) days of Employee’s termination of employment, provided that if such sixty (60)-day period spans two calendar years,
payments shall commence in the latter calendar year.

  

C.           Termination
Upon a Change of Control. If the Company or any successor in interest to the Company terminates Employees employment in connection
with or within twelve (12) months after a Change of Control (defined below), Employee shall be entitled to receive continuing bi-weekly
payments of severance pay at a rate equal to Employee’s Base Salary, as then in effect, for six (6) months from the date
of termination of employment, less all required tax withholdings and other applicable deductions, payable in accordance with the
Company’s standard payroll procedures, commencing on the effective date of a separation agreement with a complete release
of claims against the Company; provided that the first payment shall include any amounts that would have been paid to Employee
if payment had commenced on the date of separation from service; and further provided that Employee shall not be required to execute
a release of any claims arising from the Company’s failure to comply with its obligations under Paragraph 12A above. The
payments described in this Paragraph 12C are in lieu of, and not in addition to, the payments described in paragraph 12B, it being
understood by Employee that he shall be paid only one severance. Notwithstanding the previous provisions of this Paragraph 12C,
any payments due under this Paragraph 12C shall commence within sixty (60) days of Employee’s termination of employment,
provided that if such sixty (60)-day period spans two calendar years, payments shall commence in the latter calendar year.

  

D.           Termination
for Cause, Death or Disability, or Resignation Without Good Reason. If Employee’s employment with the Company terminates
voluntarily by Employee without Good Reason, for Cause by the Company or due to Employee’s death or disability, then payments
of compensation by the Company to Employee hereunder will terminate immediately (except as to amounts already earned).

  

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F.           Definitions.

 

(1)         “Cause.”
For all purposes under this Agreement, “Cause” is defined as (i) gross negligence or willful misconduct in the performance
of Employee’s duties and responsibilities to the Company; (ii) commission of any act of fraud, theft, embezzlement, financial
dishonesty or any other willful misconduct that has caused or is reasonably expected to result in injury to the Company; (iii)
conviction of, or pleading guilty or nolo contendere to, any felony or a lesser crime involving dishonesty or moral turpitude;
or (iv) material breach by Employee of any of obligations under any written agreement or covenant with the Company, including
the policies adopted from time to time by the Company applicable to all employees.

 

(2)         “Good
Reason.” For all purposes under this Agreement, “Good Reason” is defined as Employee’s resignation
within thirty (30) days following the expiration of any Company cure period (discussed below) following the occurrence of one or
more of the following, without Employee’s express written consent (i) a material reduction of Employee’s duties, authority
or responsibilities, relative to Employee’s duties, authority or responsibilities in effect immediately prior to such reduction;
(ii) a material reduction in Employee’s base compensation; or (iii) a material breach by the Company under any written agreement
or covenant with Employee. Employee will not resign for Good Reason without first providing the Company with written notice within
thirty (30) days of the event that Employee believes constitutes “Good Reason” specifically identifying the acts or
omissions constituting the grounds for Good Reason and a reasonable cure period of not less than thirty (30) days following the
date of such notice during which such condition shall not have been cured.

 

(3)         “Change
of Control.” For all purposes under
this Agreement, “Change of Control” of the Company is defined as:

 

(a)          a
sale, transfer or disposition of all or substantially all of the Company’s assets other than to (i) a corporation or other
entity of which at least a majority of its combined voting power is owned directly or indirectly by the Company, (ii) a corporation
or other entity owned directly or indirectly by the holders of capital stock of the Company in substantially the same proportions
as their ownership of Company common stock, or (iii) an Excluded Entity (as defined below); or

 

(b)          any
merger, consolidation or other business combination transaction of the Company with or into another corporation, entity or person,
other than a transaction with or into an Excluded Entity, being another corporation, entity or person in which the holders of at
least a majority of the shares of voting capital stock of the Company outstanding immediately prior to such transaction continue
to hold (either by such shares remaining outstanding in the continuing entity or by their being converted into shares of voting
capital stock of the surviving entity) a majority of the total voting power represented by the shares of voting capital stock of
the Company (or the surviving entity) outstanding immediately after such transaction; or

 

(c)          any
acquisition of at least a majority of the shares of voting capital stock of the Company by any corporation, entity or person or
group of corporations, entities or persons acting in concert, other than an Excluded Entity.

 

For
the avoidance of doubt, a liquidation, dissolution or winding up of the Company or change in the state of the Company’s incorporation
shall not constitute a Change of Control event for purposes of this Agreement.

 

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F.           Exclusive
Remedy. In the event of a termination
of Employee’s employment with the Company, the provisions of this Paragraph 12
are intended to be and are exclusive and in lieu of any other rights or remedies to which Employee or the Company may
otherwise be entitled.

 

13.              GENERAL
PROVISIONS.

 

A.           Governing
Law; Consent To Personal Jurisdiction. The
laws of the State of Colorado govern this Agreement without regard to conflict of laws principles. Employee and the Company each
hereby consents to the personal jurisdiction of the state courts located in the City and County of Denver, State of Colorado, and
the federal district court sitting in the City and County of Denver, State of Colorado, if that court otherwise possesses jurisdiction
over the matter, for any legal proceeding concerning Employee’s employment or termination of employment, or arising from
or related to this Agreement or any other agreement executed between Employee and the Company. Should an action be brought to enforce
the terms of this Agreement, the prevailing party shall be entitled to recover reasonable attorneys’ fees and costs incurred
in prosecuting the action.

 

B.           Entire
Agreement. This Agreement sets forth this
entire Agreement between the Company (and any of its related or affiliated entities, officers, agents, owners or representatives)
and Employee relating to the subject matter herein, and supersedes any and all prior discussions and agreements, whether written
or oral, on the subject matter hereof. To the extent that this Agreement may conflict with the terms of another written agreement
between Employee and the Company, the terms of this Agreement will control.

 

C.           Modification.
No modification of or amendment to this Agreement will be effective unless in writing and signed by Employee and an authorized
representative of the Company.

 

D.           Waiver.
The Company’s failure to enforce any provision of this Agreement shall not act as a waiver of its ability to enforce that provision
or any other provision. The Company’s failure to enforce any breach of this Agreement shall not act as a waiver of that
breach or any future breach. No waiver of any of the Company’s rights under this Agreement will be effective unless in writing.
Any such written waiver shall not be deemed a continuing waiver unless specifically stated, and shall operate only as to the specific
term or condition waived and shall not constitute a waiver of such term or condition for the future or as to any act other than
that specifically waived.

 

E.           Successors
and Assigns. This Agreement shall be assignable
to, and shall inure to the benefit of, the Company’s successors and assigns. Employee shall not have the right to assign
his/her rights or obligations under this Agreement.

 

F.           Construction.
The language used in this Agreement will be deemed to be language chosen by Employee and the Company to express their mutual intent,
and no rules of strict construction will be applied against either party.

 

G.           Counterparts.
This Agreement may be executed in any number of counterparts, each of which shall be enforceable, and all of which together shall
constitute one agreement. Signatures of the Parties that are transmitted in person or by facsimile or e-mail shall be accepted
as originals.

 

	Confidential: Employment Agreement:  Robert DiSilvio	Please initial each page:	

 

    	Page 10

    	 

    

 

 

H.           Further
Assurances. Employee agrees to execute any proper oath or verify any document required to carry out the terms of this Agreement.

 

I.           Title
and Headings. The titles, captions and headings of this Agreement are included for ease of reference only and will be disregarded
in interpreting or construing this Agreement.

 

J.           Notices.
All notices and communications that are required or permitted to be given under this Agreement shall be in writing and shall be
sufficient in all respects if given and delivered in person, by electronic mail, by facsimile, by overnight courier, or by certified
mail, postage prepaid, return receipt requested, to the receiving party at such party’s address shown in the signature blocks
below or to such other address as such party may have given to the other by notice pursuant to this Paragraph. Notice shall be
deemed given (i) on the date of delivery in the case of personal delivery, electronic mail or facsimile, or (ii) on the delivery
or refusal date as specified on the return receipt in the case of certified mail or on the tracking report in the case of overnight
courier.

 

K.         409A.
The amounts payable under this Agreement are intended to be exempt from the requirements of Section 409A of the Internal Revenue
Code of 1986, as amended (“Section 409A”). To the extent that any such payments are determined to be subject to Section
409A, (i) the terms of this Agreement shall be interpreted to avoid incurring any penalties under Section 409A, (ii) any payments
due upon a termination of employment shall only be payable if the termination constitutes a “separation from service”
within the meaning of Section 409A, (iii) any right to a series of installment payments is to be treated as a right to a series
of separate payments, and (iv) any payments due to a “specified employee” of a publicly- traded company upon a separation
from service shall be delayed until the first day of the seventh month following such separation from service. Notwithstanding
the foregoing, in no event shall the Company be responsible for any taxes or penalties due under Section 409A.

 

14.              EMPLOYEE’S
ACKNOWLEDGMENTS. Employee acknowledges that he/she is executing
this Agreement voluntarily and without duress or undue influence by the Company or anyone else and that Employee has carefully
read this Agreement and fully understands the terms, consequences, and binding effect of this Agreement.

 

IN
WITNESS WHEREOF, and intending to be legally bound, the parties have executed this Employment Agreement as of the date first written
above.

 

	EMPLOYEE	 	BACTERIN INTERNATIONAL, INC.
	 	 	 	 	 
	Print Name:	Robert DiSilvio	 	Print Name:	Daniel Goldberger
	 	 	 	 	 
	Signature:	/s/ Robert DiSilvio	 	Signature:	/s/ Daniel Goldberger
	 	 	 	 	 
	Date:	5 June 2014	 	Title:	CEO
	 	 	 	 	 
	Address: 	7306 NE 120th PL Kirkland WA	 	Date:	6/5/14
	 	 	 	 	 
	Phone:	425-823-4654	 	 	 
	 	 	 	 	 
	Email:	bob@disilvio.com	 	 	 

  

	Confidential: Employment Agreement:  Robert DiSilvio	Please initial each page:	

 

    	Page 11

    	 

    

  

EXHIBIT
A 

LIST
OF PRIOR INVENTIONS AND ORIGINAL WORKS OF AUTHORSHIP

 

IS
A LIST ATTACHED? (PLEASE CHECK):  ̈YES
x
NO

 

NOTE:
The following is a list of all Prior Inventions made, conceived, developed or reduced to practice by Employee prior to his/her
employment with the Company. IF NO SUCH LIST IS ATTACHED, THAT MEANS EMPLOYEE IS NOT ASSERTING THE EXISTENCE OF ANY PRIOR INVENTIONS.

 

	Confidential: Employment Agreement:  Robert DiSilvio	Please initial each page:	

 

    	Page 12

    	 

    

 

EXHIBIT B

 

TERMINATION
CERTIFICATE

 

I
hereby represent and certify that I have in all material respects complied with my obligations to the Company under the Employment
Agreement between the Company and me to which the form of this Certificate is attached as Exhibit B.

 

I
also represent that on or before my last day, I have specifically returned the following items:

 

	 	 ̈	Computer/laptop	 
	 	 	 	 
	 	 ̈	Keys/access cards	 
	 	 	 	 
	 	 ̈	Company credit card	 
	 	 	 	 
	 	 ̈	Other equipment (please list)	 

 

	Confidential: Employment Agreement:  Robert DiSilvio	Please initial each page:	

 

    	Page 13Exhibit
10.10

 

BACTERIN
INTERNATIONAL HOLDINGS, INC. 

 

NON-PLAN
INDUCEMENT STOCK OPTION GRANT

 

This Agreement between Bacterin International Holdings, Inc.
(the “Company”) and Robert Di Silvio (the “Option Holder”) is effective as of the Grant Date.

 

1.          Grant
of Option. The Company hereby grants the Option Holder
a Non Qualified Stock Option to purchase 550,000 shares of common stock, $0.000001 par value per share, of the Company under the
terms of this Agreement (the “Option”) as an inducement grant made pursuant to Section 711(a) of the NYSE MKT Company
Guide. This Option satisfies the requirements of Section 2.C of the Employment Agreement between the Company and the Option Holder
dated July 1, 2014. For avoidance of doubt, this Option is not issued under the Company’s Amended and Restated Equity Incentive
Plan (the “Plan”) and does not reduce the shares available under the Plan. The Option is not intended to qualify as
an Incentive Stock Option within the meaning of Section 422 of the Internal Revenue Code of 1986, as amended.

 

2.          Date
of Grant.
The date of the grant of the Option is July 1, 2014 (the “Grant Date”).

 

3.          Number
and Price of Shares. The number of shares of the Company’s
common stock as to which the Option is granted is five hundred fifty thousand (550,000) shares (the “Shares”). The
purchase price per Share is $0.68, which was the closing price of the Company’s common stock listed on the NYSE MKT on the
trading day immediately preceding the Grant Date.

 

4.          Vesting.
The Option granted hereby shall become vested in and exercisable
by Option Holder as set forth in the following schedule:

    	Stock Option Agreement: Robert Di Silvio	DATE: July 1, 2014     1

    	 

    

 

	 	 	 	Number of Shares	 
	Date	 	 	Which Become Exercisable	 
	 	 	 	 	 	 	 
	 	July 1,2015	 	 	 	110,000	 
	 	August 1, 2015	 	 	 	9,170	 
	 	September 1, 2015	 	 	 	9,170	 
	 	October 1, 2015	 	 	 	9,170	 
	 	November 1, 2015	 	 	 	9,170	 
	 	December 1, 2015	 	 	 	9,170	 
	 	January 1, 2016	 	 	 	9,170	 
	 	February 1, 2016	 	 	 	9,170	 
	 	March 1,2016	 	 	 	9,170	 
	 	April 1,2016	 	 	 	9,170	 
	 	May 1, 2016	 	 	 	9,170	 
	 	June 1, 2016	 	 	 	9,170	 
	 	July 1,2016	 	 	 	9,170	 
	 	August 1, 2016	 	 	 	9,170	 
	 	September 1, 2016	 	 	 	9,170	 
	 	October 1, 2016	 	 	 	9,170	 
	 	November 1, 2016	 	 	 	9,170	 
	 	December 1, 2016	 	 	 	9,170	 
	 	January 1, 2017	 	 	 	9,170	 
	 	February 1,2017	 	 	 	9,170	 
	 	March 1, 2017	 	 	 	9,170	 
	 	April 1,2017	 	 	 	9,170	 
	 	May 1, 2017	 	 	 	9,170	 
	 	June 1, 2017	 	 	 	9,170	 
	 	July 1,2017	 	 	 	9,170	 
	 	August 1, 2017	 	 	 	9,170	 
	 	September 1, 2017	 	 	 	9,170	 
	 	October 1, 2017	 	 	 	9,170	 
	 	November 1, 2017	 	 	 	9,170	 
	 	December 1, 2017	 	 	 	9,170	 
	 	January 1, 2018	 	 	 	9,170	 
	 	February 1, 2018	 	 	 	9,170	 
	 	March 1, 2018	 	 	 	9,170	 
	 	April 1,2018	 	 	 	9,170	 
	 	May 1,2018	 	 	 	9,170	 
	 	June 1, 2018	 	 	 	9,170	 
	 	July 1,2018	 	 	 	9,170	 
	 	August 1, 2018	 	 	 	9,170	 
	 	September 1, 2018	 	 	 	9,170	 
	 	October 1, 2018	 	 	 	9,170	 
	 	November 1, 2018	 	 	 	9,170	 
	 	December 1, 2018	 	 	 	9,170	 
	 	January 1, 2019	 	 	 	9,170	 
	 	February 1,2019	 	 	 	9,170	 
	 	March 1,2019	 	 	 	9,170	 
	 	April I, 2019	 	 	 	9,170	 
	 	May 1, 2019	 	 	 	9,170	 
	 	June 1, 2019	 	 	 	9,170	 
	 	July 1,2019	 	 	 	9,010	 

 

In
order to be eligible to exercise the Option in accordance with the vesting schedule, the Option Holder must have been continuously
employed by the Company from the Grant Date of the Option until the date specified in the vesting schedule.

 

Acceleration
of Exercisability. Upon a Change in Control
(defined below) of the Company, then (i) the entire Option shall immediately be 100% vested without regard to the schedule contained
in this Option Agreement and (ii) the entire Option shall become immediately exercisable in full during its remaining term. The
Option Holder may exercise the Option at any time immediately after or concurrently with a Change in Control regardless of whether
all conditions of exercise have been satisfied.

 

5.            Manner
of Exercise. The vested
portion of the Option may be exercised by delivery to the Company of (i) a written notice of exercise, specifying the number of
Shares with respect to which such Option is exercised, and (ii) payment in full of the exercise price and any liability the Company
may have for withholding of federal, state or local income or other taxes incurred by reason of the exercise of the Option.

 

    	Stock Option Agreement: Robert Di Silvio	DATE: July 1, 2014     2

    	 

    

   

6.           Legends.
Certificates representing shares of common stock of the Company
acquired upon exercise of this Option may contain a legend restricting transfer of the stock until there has been compliance with
applicable federal and state securities laws.

 

7.           Term.
Unless terminated earlier pursuant to Section 8 below, the
Option will expire ten (10) years from the Grant Date on July 1,2024.

 

8.           Effect
of Termination of Employment. The Option
shall not betransferable by the Option Holder except by will or pursuant to
the laws of descent and distribution. The Option is exercisable during the Option Holder’s lifetime only by the Option
Holder, or in the event of disability or incapacity, by his guardian or legal representative. In the event of termination of
the Option Holder’s employment other than for Cause (including, without limitation, by reason of the Option
Holder’s death or disability, which results in the Option Holder’s inability to perform substantially all of the
duties of his position for more than 120 consecutive days) or resignation of the Option Holder for Good Reason (as those
terms are defined below) the Option will expire ninety (90) days after the effective date of cessation of the Option
Holder’s employment. In the event of termination of the Option Holder’s employment for Cause or the Option
Holder’s resignation for other than Good Reason, the Option will expire at the effective date and time of cessation of
the Option Holder’s employment.

 

9.           Definitions.

 

“Cause.”
For all purposes under this Agreement, “Cause” is defined as (i) gross negligence or willful misconduct in the
performance of the Option Holder’s duties and responsibilities to the Company; (ii) commission of any act of fraud, theft,
embezzlement, financial dishonesty or any other willful misconduct that has caused or is reasonably expected to result in injury
to the Company; (iii) conviction of, or pleading guilty or nolo contendere to, any felony or a lesser crime involving dishonesty
or moral turpitude; or (iv) material breach by the Option Holder of any obligations under any written agreement or covenant with
the Company.

 

“Good
Reason.” For all purposes under this Agreement, “Good Reason” is defined as the Option
Holder’s resignation within thirty (30) days following the expiration of any Company cure period (discussed below)
following the occurrence of one or more of the following, without the Option Holder’s express written consent: (i) a
material reduction of the Option Holder’s duties, authority or responsibilities, relative to the Option Holder’s
duties, authority or responsibilities in effect immediately prior to such reduction; (ii) a material reduction in the Option
Holder’s base compensation; or (iii) a material breach by the Company under any written agreement or covenant with the
Option Holder; provided, however that the Option Holder does not resign for Good Reason without first providing the Company
with written notice within thirty (30) days of the event that the Option Holder believes constitutes “Good
Reason” specifically identifying the acts or omissions constituting the grounds for Good Reason and a reasonable cure
period of not less than thirty (30) days following the date of such notice during which such condition shall not have been
cured.

 

    	Stock Option Agreement: Robert Di Silvio	DATE: July 1, 2014     3

    	 

    

 

“Change
of Control.” For all purposes under this Agreement, “Change of Control” of the Company is defined as:

 

(a)          a
sale, transfer or disposition of all or substantially all of the Company’s assets other than to (A) a corporation or other
entity of which at least a majority of its combined voting power is owned directly or indirectly by the Company, (B) a corporation
or other entity owned directly or indirectly by the holders of capital stock of the Company in substantially the same proportions
as their ownership of Company common stock, or (C) an Excluded Entity (as defined below); or

 

(b)          any
merger, consolidation or other business combination transaction of the Company with or into another corporation, entity or person,
other than a transaction with or into an Excluded Entity, being another corporation, entity or person in which the holders of at
least a majority of the shares of voting capital stock of the Company outstanding immediately prior to such transaction continue
to hold (either by such shares remaining outstanding in the continuing entity or by their being converted into shares of voting
capital stock of the surviving entity) a majority of the total voting power represented by the shares of voting capital stock of
the Company (or the surviving entity) outstanding immediately after such transaction; or

 

(c)          any
acquisition of at least a majority of the shares of voting capital stock of the Company by any corporation, entity or person or
group of corporations, entities or persons acting in concert, other than an Excluded Entity,

 

For
the avoidance of doubt, a liquidation, dissolution or winding up of the Company or change in the state of the Company’s incorporation
shall not constitute a Change of Control event for purposes of this Agreement.

 

10,          Adjustments
for Stock Splits and Dividends. If the Company shall at
any time increase or decrease the number of its outstanding shares of common stock or change in any way the rights and privileges
of such shares by means of the payment of a stock dividend or any other distribution upon such shares payable in stock, or through
a stock split, subdivision, consolidation, combination, reclassification or recapitalization involving the stock, then in relation
to the stock that is affected by one or more of the above events, the numbers, rights and privileges of the shares underlying this
Option shall be increased, decreased or changed in like manner (in accordance with the rules governing modifications, extensions,
substitutions and assumptions of stock rights described in Treas. Reg. § 1.409A-l(b)(5)(v)(D)) as if they had been issued
and outstanding, fully paid and nonassessable at the time of such occurrence; provided, however, that no adjustment shall require
the Company to issue a fractional share under any circumstance, and the total adjustment shall be limited by deleting any fractional
share.

 

    	Stock Option Agreement: Robert Di Silvio	DATE: July 1, 2014     4

    	 

    

 

IN
WITNESS WHEREOF, this Agreement is effective as of the Grant Date.

 

	 	BACTERIN INTERNATIONAL HOLDINGS, INC.

 

	 	By	/s/
Daniel Goldberger
	 	Name: 	Daniel Goldberger
	 	Title:	CEO
	 	 	 
	 	OPTION
    HOLDER
	 	 
	 	/s/ Robert Di Silvio
	 	Robert Di Silvio

 

    	Stock Option Agreement: Robert Di Silvio	DATE: July 1, 2014     5

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