Document:

exv4w20

Exhibit 4.20

     TENTH SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of March
19, 2010, among NEW BINAX, INC., NEW BIOSITE INCORPORATED, ALERE NEWCO, INC., AND ALERE NEWCO II, INC. (the
“New Guarantors”), Subsidiaries of Inverness Medical Innovations, Inc. (or its successor) (the
“Issuer”), INVERNESS MEDICAL INNOVATIONS, INC., a Delaware corporation, each of the Guarantors (the
“Existing Guarantors”) under the Indenture referred to below, and THE BANK OF NEW YORK MELLON TRUST
COMPANY, N.A., as Trustee under the Indenture referred to below (the “Trustee”).

WITNESSETH:

     WHEREAS the Issuer has heretofore executed and delivered to the Trustee an Indenture dated as
of August 11, 2009, as amended, supplemented and modified by a First Supplemental Indenture dated
as of August 11, 2009, a Second Supplemental Indenture dated as of September 22, 2009, a Fourth
Supplemental Indenture dated as of November 25, 2009, a Sixth Supplemental Indenture dated as of
February 1, 2010, and an Eighth Supplemental Indenture dated as of March 1, 2010 (as so amended,
supplemented or modified, and as further amended, supplemented or modified to date, the
“Indenture”), by and among the Issuer, the Existing Guarantors and the Trustee, providing for the
issuance of 7.875% Senior Notes due 2016 (the “Notes”);

     WHEREAS Section 4.13 of the Indenture provides that under certain circumstances the Issuer is
required to cause each of the New Guarantors to execute and deliver to the Trustee a supplemental
indenture pursuant to which each of the New Guarantors shall unconditionally and irrevocably
guarantee all of the Issuer’s obligations under the Notes pursuant to a guarantee on the terms and
conditions set forth herein; and

     WHEREAS pursuant to Section 9.01 of the Indenture, the Trustee, the Issuer and the Existing
Guarantors are authorized to execute and deliver this Supplemental Indenture;

     NOW THEREFORE, in consideration of the foregoing and for other good and valuable
consideration, the receipt of which is hereby acknowledged, each of the New Guarantors, the
Trustee, the Issuer and the Existing Guarantors mutually covenant and agree for the equal and
ratable benefit of the Holders as follows:

     SECTION 1. Definitions. For all purposes of this Supplemental Indenture, except as
otherwise herein expressly provided or unless the context otherwise requires: (i) the terms and
expressions used herein shall have the same meanings as corresponding terms and expressions used in
the Indenture; and (ii) the words “herein,” “hereof” and “hereby” and other words of similar import
used in this Supplemental Indenture refer to this Supplemental Indenture as a whole and not to any
particular section hereof.

     SECTION 2. Agreement to Guarantee. Each of the New Guarantors hereby unconditionally
and irrevocably agrees, jointly and severally with all other Guarantors, to guarantee the Issuer’s
obligations under the Notes and the Indenture on the terms and subject to the conditions set forth
in Article Ten of the Indenture and to be bound by all other applicable provisions of the
Indenture.

 

 

     SECTION 3. Ratification of Indenture; Supplemental Indenture Part of Indenture.
Except as expressly amended hereby, the Indenture is in all respects ratified and confirmed and all
the terms, conditions and provisions thereof shall remain in full force and effect. This
Supplemental Indenture shall form a part of the Indenture for all purposes, and every Holder
heretofore or hereafter authenticated and delivered shall be bound hereby.

     SECTION 4. Governing Law. This Supplemental Indenture shall be governed by, and
construed in accordance with, the laws of the State of New York, but without giving effect to
applicable principles of conflicts of laws to the extent that the application of the laws of
another jurisdiction would be required thereby.

     SECTION 5. Trustee Makes No Representation. The Trustee makes no representation as to
the validity or sufficiency of this Supplemental Indenture or for the recitals contained herein.

     SECTION 6. Counterparts. The parties may sign any number of copies of this
Supplemental Indenture. Each signed copy shall be an original, but all of them together represent
the same agreement.

     SECTION 7. Effect of Headings. The Section headings herein are for convenience only
and shall not effect the construction thereof.

[Signature Page Follows]

- 2 -

 

     IN WITNESS WHEREOF, the parties hereto have caused this Supplemental Indenture to be duly
executed as of the date first above written.

	 	 	 	 	 
	 	NEW GUARANTORS:

ALERE NEWCO, INC.

ALERE NEWCO II, INC.

NEW BINAX, INC.

NEW BIOSITE INCORPORATED,
  as
New Guarantors

 	 
	 	   By:  	/s/ David A. Teitel
 	 
	 	 	Name:  	David A. Teitel 	 
	 	 	Title (respectively): President; President; Vice
President, Finance; Vice President, Finance 
	 
	 

Signature Page to Tenth Supplemental Indenture (7.875% Notes — Public)

 

 

	 	 	 	 	 
	 	ISSUER:

INVERNESS MEDICAL INNOVATIONS, INC.

 	 
	 	By:  	/s/ David A. Teitel
 	 
	 	 	Name:  	David A. Teitel 	 
	 	 	Title:  	Chief Financial Officer and Treasurer 	 
	 

Signature Page to Tenth Supplemental Indenture (7.875% Notes — Public)

 

 

EXISTING GUARANTORS:

ALERE HEALTH, LLC

ALERE HEALTHCARE OF ILLINOIS, INC.

ALERE HEALTH IMPROVEMENT COMPANY

ALERE HEALTH SYSTEMS, INC.

ALERE MEDICAL, INC.

ALERE WELLOLOGY, INC.

ALERE WOMEN’S AND CHILDREN’S HEALTH, LLC

AMEDITECH INC.

APPLIED BIOTECH, INC.

BINAX, INC.

BIOSITE INCORPORATED

CHOLESTECH CORPORATION

FIRST CHECK DIAGNOSTICS CORP.

FIRST CHECK ECOM, INC.

FREE & CLEAR, INC.

GENECARE MEDICAL GENETICS CENTER, INC.

HEMOSENSE, INC.

IM US HOLDINGS, LLC

	 	 	 	 	 
	 	By:  	                         /s/ David A. Teitel
 	 
	 	 	Name:  	David A. Teitel 	 
	 	 	Title (respectively):  Vice President and
Treasurer; Vice President, Finance; Vice
President, Finance; Vice President and
Treasurer; Vice President and Treasurer;
Vice President, Finance; Vice President,
Finance; General Manager; Vice President;
Vice President, Finance; Vice President,
Finance; Vice President, Finance and Chief
Financial Officer; Vice President, Finance;
Vice President; Vice President, Finance and
Treasurer; Vice President and Treasurer;
Treasurer; President 
	 
	 

Signature Page to Tenth Supplemental Indenture (7.875% Notes — Public)

 

 

EXISTING GUARANTORS (continued):

INNOVACON, INC.

INNOVATIVE MOBILITY, LLC

INSTANT TECHNOLOGIES, INC.

INVERNESS MEDICAL, LLC

INVERNESS MEDICAL — BIOSTAR INC.

INVERNESS MEDICAL INNOVATIONS NORTH AMERICA, INC.

INVERNESS MEDICAL INTERNATIONAL HOLDING CORP.

ISCHEMIA TECHNOLOGIES, INC.

IVC INDUSTRIES, INC.

MATRITECH, INC.

OSTEX INTERNATIONAL, INC.

QUALITY ASSURED SERVICES, INC.

REDWOOD TOXICOLOGY LABORATORY, INC.

RMD NETWORKS, INC.

RTL HOLDINGS, INC.

SELFCARE TECHNOLOGY, INC.

TAPESTRY MEDICAL, INC.

WAMPOLE LABORATORIES, LLC

ZYCARE, INC.

	 	 	 	 	 
	 	By:  	                         /s/ David A. Teitel
 	 
	 	 	Name:  	David A. Teitel 	 
	 	 	Title (respectively):  Vice President, Finance;
Chief Financial Officer; Vice President,
Finance; Vice President, Finance; Vice
President, Finance; Vice President, Finance;
President; Vice President, Finance; Vice
President; Vice President, Finance; Vice
President, Finance; Chief Financial Officer;
Vice President, Finance; Vice President,
Finance and Treasurer; Vice President,
Finance; Vice President, Finance; Vice
President, Finance; Vice President; Chief
Financial Officer and Treasurer 
	 
	 

Signature Page to Tenth Supplemental Indenture (7.875% Notes — Public)

 

 

	 	 	 	 	 
	 	EXISTING GUARANTORS (continued):

KROLL LABORATORY SPECIALISTS, INC.

LABORATORY SPECIALISTS OF AMERICA, INC.

SCIENTIFIC TESTING LABORATORIES, INC.

 	 
	 	By:  	/s/ Jay McNamara
 	 
	 	 	Name:  	Jay McNamara 	 
	 	 	Title:  	Assistant Secretary 	 
	 

Signature Page to Tenth Supplemental Indenture (7.875% Notes — Public)

 

 

	 	 	 	 	 
	 	EXISTING GUARANTORS (continued):

MATRIA OF NEW YORK, INC.

 	 
	 	By:  	                /s/ Tom Underwood
 	 
	 	 	Name:  	Tom Underwood 	 
	 	 	Title:  	President 	 
	 

Signature Page to Tenth Supplemental Indenture (7.875% Notes — Public)

 

 

	 	 	 	 	 
	 	TRUSTEE:

THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A.,

as Trustee

 	 
	 	By:  	/s/ Peter Murphy
 	 
	 	 	Name:  	Peter Murphy 	 
	 	 	Its: Vice President 	 
	 

Signature Page to Tenth Supplemental Indenture (7.875% Notes — Public)exv4w21

Exhibit 4.21

          ELEVENTH SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of March
19, 2010, among NEW BINAX, INC., NEW BIOSITE INCORPORATED, ALERE NEWCO, INC., AND ALERE NEWCO II, INC.
( the “New Guarantors”), Subsidiaries of Inverness Medical Innovations, Inc. (or its successor)
(the “Issuer”), INVERNESS MEDICAL INNOVATIONS, INC., a Delaware corporation, each of the Guarantors
(the “Existing Guarantors”) under the Indenture referred to below, and THE BANK OF NEW YORK MELLON
TRUST COMPANY, N.A., as Trustee under the Indenture referred to below (the “Trustee”).

WITNESSETH:

          WHEREAS the Issuer has heretofore executed and delivered to the Trustee an Indenture dated as
of August 11, 2009, as amended, supplemented and modified by a Third Supplemental Indenture dated
as of September 28, 2009, a Fifth Supplemental Indenture dated as of November 25, 2009, a Seventh
Supplemental Indenture dated as of February 1, 2010, and a Ninth Supplemental Indenture dated as of
March 1, 2010 (as so amended, supplemented or modified, and as further amended, supplemented or
modified to date, the “Indenture”), by and among the Issuer, the Existing Guarantors and the
Trustee, providing for the issuance of 7.875% Senior Notes due 2016 (the “Notes”);

          WHEREAS Section 4.13 of the Indenture provides that under certain circumstances the Issuer is
required to cause each of the New Guarantors to execute and deliver to the Trustee a supplemental
indenture pursuant to which each of the New Guarantors shall unconditionally and irrevocably
guarantee all of the Issuer’s obligations under the Notes pursuant to a guarantee on the terms and
conditions set forth herein; and

          WHEREAS pursuant to Section 9.01 of the Indenture, the Trustee, the Issuer and the Existing
Guarantors are authorized to execute and deliver this Supplemental Indenture;

          NOW THEREFORE, in consideration of the foregoing and for other good and valuable
consideration, the receipt of which is hereby acknowledged, each of the New Guarantors, the
Trustee, the Issuer and the Existing Guarantors mutually covenant and agree for the equal and
ratable benefit of the Holders as follows:

          SECTION 1. Definitions. For all purposes of this Supplemental Indenture, except as
otherwise herein expressly provided or unless the context otherwise requires: (i) the terms and
expressions used herein shall have the same meanings as corresponding terms and expressions used in
the Indenture; and (ii) the words “herein,” “hereof” and “hereby” and other words of similar import
used in this Supplemental Indenture refer to this Supplemental Indenture as a whole and not to any
particular section hereof.

          SECTION 2. Agreement to Guarantee. Each of the New Guarantors hereby unconditionally
and irrevocably agrees, jointly and severally with all other Guarantors, to guarantee the Issuer’s
obligations under the Notes and the Indenture on the terms and subject to the conditions set forth
in Article Ten of the Indenture and to be bound by all other applicable provisions of the
Indenture.

 

 

          SECTION 3. Ratification of Indenture; Supplemental Indenture Part of Indenture.
Except as expressly amended hereby, the Indenture is in all respects ratified and confirmed and all
the terms, conditions and provisions thereof shall remain in full force and effect. This
Supplemental Indenture shall form a part of the Indenture for all purposes, and every Holder
heretofore or hereafter authenticated and delivered shall be bound hereby.

          SECTION 4. Governing Law. This Supplemental Indenture shall be governed by, and
construed in accordance with, the laws of the State of New York, but without giving effect to
applicable principles of conflicts of laws to the extent that the application of the laws of
another jurisdiction would be required thereby.

          SECTION 5. Trustee Makes No Representation. The Trustee makes no representation as to
the validity or sufficiency of this Supplemental Indenture or for the recitals contained herein.

          SECTION 6. Counterparts. The parties may sign any number of copies of this
Supplemental Indenture. Each signed copy shall be an original, but all of them together represent
the same agreement.

          SECTION 7. Effect of Headings. The Section headings herein are for convenience only
and shall not effect the construction thereof.

[Signature Page Follows]

- 2 -

 

          IN WITNESS WHEREOF, the parties hereto have caused this Supplemental Indenture to be duly
executed as of the date first above written.

	 	 	 	 	 
	 	NEW GUARANTORS:

ALERE NEWCO, INC.

ALERE NEWCO II, INC.

NEW BINAX, INC.

NEW BIOSITE INCORPORATED,

  as New Guarantors

 	 
	 	By:  	/s/ David A. Teitel
 	 
	 	 	Name:  	David A. Teitel 	 
	 	 	Title (respectively):  President; President;

          Vice President, Finance; Vice

          President, Finance 	 
	 

Signature Page to Eleventh Supplemental Indenture (7.875% Notes — 144A)

 

 

	 	 	 	 	 
	 	ISSUER:

INVERNESS MEDICAL INNOVATIONS, INC.

 	 
	 	By:  	/s/ David A. Teitel
 	 
	 	 	Name:  	David A. Teitel 	 
	 	 	Title:  	Chief Financial Officer and Treasurer 	 
	 

Signature Page to Eleventh Supplemental Indenture (7.875% Notes — 144A)

 

 

	 	 	 	 	 
	 	EXISTING GUARANTORS:

ALERE HEALTH, LLC

ALERE HEALTHCARE OF ILLINOIS, INC.

ALERE HEALTH IMPROVEMENT COMPANY

ALERE HEALTH SYSTEMS, INC.

ALERE MEDICAL, INC.

ALERE WELLOLOGY, INC.

ALERE WOMEN’S AND CHILDREN’S HEALTH, LLC

AMEDITECH INC.

APPLIED BIOTECH, INC.

BINAX, INC.

BIOSITE INCORPORATED

CHOLESTECH CORPORATION

FIRST CHECK DIAGNOSTICS CORP.

FIRST CHECK ECOM, INC.

FREE & CLEAR, INC.

GENECARE MEDICAL GENETICS CENTER, INC.

HEMOSENSE, INC.

IM US HOLDINGS, LLC

 	 
	 	By:  	/s/ David A. Teitel
 	 
	 	 	Name:  	David A. Teitel 	 
	 	 	Title (respectively):  Vice President and 

          Treasurer; Vice President, Finance; Vice

          President, Finance; Vice President and

          Treasurer; Vice President and Treasurer;

          Vice President, Finance; Vice President,

          Finance; General Manager; Vice President;

          Vice President, Finance; Vice President,

          Finance; Vice President, Finance and Chief

          Financial Officer; Vice President, Finance;

          Vice President; Vice President, Finance and

          Treasurer; Vice President and Treasurer; Treasurer;

          President 	 
	 

Signature Page to Eleventh Supplemental Indenture (7.875% Notes — 144A)

 

 

	 	 	 	 	 
	 	EXISTING GUARANTORS (continued):

INNOVACON, INC.

INNOVATIVE MOBILITY, LLC

INSTANT TECHNOLOGIES, INC.

INVERNESS MEDICAL, LLC

INVERNESS MEDICAL — BIOSTAR INC.

INVERNESS MEDICAL INNOVATIONS NORTH AMERICA, INC.

INVERNESS MEDICAL INTERNATIONAL HOLDING CORP.

ISCHEMIA TECHNOLOGIES, INC.

IVC INDUSTRIES, INC.

MATRITECH, INC.

OSTEX INTERNATIONAL, INC.

QUALITY ASSURED SERVICES, INC.

REDWOOD TOXICOLOGY LABORATORY, INC.

RMD NETWORKS, INC.

RTL HOLDINGS, INC.

SELFCARE TECHNOLOGY, INC.

TAPESTRY MEDICAL, INC.

WAMPOLE LABORATORIES, LLC

ZYCARE, INC.

 	 
	 	By:  	/s/ David A. Teitel
 	 
	 	 	Name:  	David A. Teitel 	 
	 	 	Title (respectively):  Vice President, Finance;

          Chief Financial Officer; Vice President,

          Finance; Vice President, Finance; Vice

          President, Finance; Vice President, Finance;

          President; Vice President, Finance; Vice

          President; Vice President, Finance; Vice

           President, Finance; Chief Financial Officer;

          Vice President, Finance; Vice President,

          Finance and Treasurer; Vice President,

          Finance; Vice President, Finance; Vice

          President, Finance; Vice President; Chief Financial

          Officer and Treasurer 	 
	 

Signature Page to Eleventh Supplemental Indenture (7.875% Notes — 144A)

 

 

	 	 	 	 	 
	 	EXISTING GUARANTORS (continued):

KROLL LABORATORY SPECIALISTS, INC.

LABORATORY SPECIALISTS OF AMERICA, INC.

SCIENTIFIC TESTING LABORATORIES, INC.

 	 
	 	By:  	/s/ Jay McNamara
 	 
	 	 	Name:  	Jay McNamara 	 
	 	 	Title:  	Assistant Secretary 	 
	 

Signature Page to Eleventh Supplemental Indenture (7.875% Notes — 144A)

 

 

	 	 	 	 	 
	 	EXISTING GUARANTORS (continued):

MATRIA OF NEW YORK, INC.

 	 
	 	By:  	/s/ Tom Underwood
 	 
	 	 	Name:  	Tom Underwood 	 
	 	 	Title:  	President 	 
	 

Signature Page to Eleventh Supplemental Indenture (7.875% Notes — 144A)

 

 

	 	 	 	 	 
	 	TRUSTEE:

THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A.,

  as Trustee

 	 
	 	By:  	/s/ Peter M. Murphy
 	 
	 	 	Name:  	Peter M. Murphy 	 
	 	 	Its: Vice President 	 
	 

Signature Page to Eleventh Supplemental Indenture (7.875% Notes — 144A)

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