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=         [NUMBER]                               [MDTI LOGO]                                   [SHARES]           =
=                                                                                                                 =
=                                                                                                                 =
=                                      MOLECULAR DIAGNOSTICS & THERAPEUTICS, INC.                                 =
=                              INCORPORATED UNDER THE LAWS OF THE STATE OF COLORADO                               =
=                   The Corporation is authorized to issue 45,000,000 Common Shares - No Par Value                =
=                                 And 5,000,000 Preferred Shares - No Par Value                                   =
=                                                                                                                 =
=                                                                                                                 =
=                                                                                                                 =
=    THIS CERTIFIES THAT                                                                                          =
=                                                                                                                 =
=    Is The Owner of                                                                                              =
=                                                                                                                 =
=    FULLY PAID AND NON-ASSESSABLE SHARES OF NO PAR VALUE COMMON STOCK OF                                         =
=                                                                                                                 =
=    MOLECULAR DIAGNOSTICS & THERAPEUTICS, INC.                                                                   =
=                                                                                                                 =
=    transferable only on the books of the Corporation by the holder hereof in person or by duly                  =
=    authorized Attorney upon surrender of this Certificate properly endorsed.                                    =
=                                                                                                                 =
=    In Witness Whereof, the said Corporation has caused this Certificate to be signed by its duly authorized     =
=    officers and to be sealed with the Seal of the Corporation.                                                  =
=                                                                                                                 =
=    Dated:                                                                                                       =
=                                                                                                                 =
=    /s/Janet Davis                       [MDTI CORPORATE SEAL]           /s/Malcolm H. Benedict                  =
=       Janet Davis, Secretary                                               Malcolm H. Benedict, President       =
=                                                                                                                 =
=                                                                                                                 =
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</TABLE>THIS SECOND AMENDMENT TO THE EMPLOYMENT AGREEMENT (hereinafter referred
to as the  "Agreement")  is entered into this 30th day of September,  1999,  and
effective as of January 1, 1999,  by and between  Nu-Tec.,  L.T.D.  (hereinafter
referred  to as the  "Employer'),  a  Colorado  corporation  with its  executive
offices located at 1880 Industrial Circle, Suite #B-3, Longmont, Colorado 80501,
and Malcolm Benedict (hereinafter referred to as the "Employee"). This Agreement
amends and supersedes  that certain  Amended  Employment  Agreement  between the
parties dated  effective as of January 1, 1996, and  terminating on December 31,
2001.

                                   WITNESSETH:

         WHEREAS:

         1. The Employer is engaged in the business of developing, manufacturing
and distributing radiochemical and radiopharmaceutical products.

         2. The Employee has certain expertise in the above-described business.

         3. The Employer desires to employ the Employee and the Employee desires
to be employed by the Employer  upon the terms and  conditions  hereinafter  set
forth.

         NOW, THEREFORE,  in consideration of the mutual promises and agreements
hereinafter  set  forth,  the  receipt  and  sufficiency  of  which  are  hereby
acknowledged, the parties hereto agree as follows:

         1.  Employment.  The  Employer  hereby  employs,  engages and hires the
Employee as the Chief Executive  Officer of the Employer and the Employee hereby
accepts and agree~ to such employment,  hiring and engagement and to the orders,
advice and direction of the Employer. The Employee, in his capacity as the Chief
Executive Officer of the Employer,  shall manage and direct the overall programs
and activities of the Employer in the  day-to-day  operations of the business of
the Employer. In addition, the Employee shall have and perform such other duties
as are customarily performed by one holding such position in other businesses or
enterprises  that are the same as or similar to that engaged in by the Employer,
and shall have and perform such unrelated duties and services as may be assigned
to him from time to time by the Board of Directors of the Employer. The Employee
agrees to abide by the Company policies and procedures  established from time to
time by the  Employer.  The exact nature of the duties of the Employee  shall be
more fully outlined and defined in a formal job description between the Employer
and the  Employee,  copies  of which,  as  amended  from time to time,  shall be
attached hereto and  incorporated  herein by this reference.  The Employee shall
accept from the Employer,  as full  compensation  for his  services,  including,
without  limitation,  any services  rendered by him as an officer or director of
the Employer or of any parent,  subsidiary  or affiliate  of the  Employer,  the
compensation  in the form of salary and shares of common stock, no par value per
share  (hereinafter  referred  to as the"  Common  Stock"),  of the  Employer as
provided in Section 4 below.
<PAGE>

         2. Best  Efforts of Employee.  The Employee  agrees that he will at all
times faithfully,  industriously and to the best of his ability,  experience and
talents perform to the reasonable satisfaction of the Employer all of the duties
that may be required of and from him pursuant to the express and implicit  terms
of this  Agreement.  Such duties  shall be rendered at 1880  Industrial  Circle,
Suite #B-3,  Longmont,  Colorado  80501,  and at such place or places and during
such  hours as the  Employer  shall in good faith  require  or as the  interest,
needs, business or opportunity of the Employer shall require.

         3. Term of Employment.  The term of this Agreement shall be a period of
three (3) years,  commencing January 1, 1999, and terminating December 31, 2001,
subject, however, to prior termination as hereinafter provided.

         4.  Compensation  of  Employee.  The  Company  shall pay or furnish the
Employee,  and the Employee shall accept from the Company,  as full compensation
for  the  Employee's  services,  including,  without  limitation,  any  services
rendered  by him as an officer or  director  of the  Employer  or of any parent,
subsidiary or affiliate of the Employer, the following compensation:

              a. A gross salary of $125,000 per annum,  payable in equal monthly
installments  once or twice per month on the first day of each month  during the
term  of this  Agreement.  New  additions  or  changes  to an  original  license
application not in the original application,  further incentive  compensation in
the minimum amount not less than $40,000 per license application will apply.

              b.  In  the  event  that  Employer  receives  major  funding  from
investment  sources,  the  Board  of  Directors  may,  in its  sole  discretion,
determine  to  pay  additional  incentive   compensation  to  Employee  for  the
performance  of services not  customarily  performed  by the  President or Chief
Executive Officer of a radiopharmaceutical company, in such amounts and forms as
shall be established by it. The nature, extent,  complexity and other factors in
connection  with such services  shall be presented to and evaluated by the Board
of  Directors  of the  Employer at a Special  Meeting of the Board of  Directors
called for that purpose.

         5. Prior  Non-Payment or  Underpayment of  Compensation.  Employer is a
start-up  company  and has,  from time to time  prior to the  execution  of this
Agreement been unable to pay Employee all compensation due to Employee under the
previous   Agreements.   Employee  hereby  waives  his  right  to  any  and  all
compensation  due to  Employee  under  the  previous  Agreements  (whether  such
compensation  was due under the original  form of this  Agreement,  or under the
First  Amended  form) for calendar  years prior to 1999,  but unpaid during such
period.   Employee  and  Employer  mutually  acknowledge  that  any  amounts  of
compensation  waived by Employee  under this  paragraph may be considered by the
Board  of  Directors  of  Employee  in  establishing  any  additional  incentive
compensation paid to Employee under paragraph 4.b. above.

           6.   Termination.

              a. This  Agreement  may be  terminated  by the Employee upon sixty
(60) days'  prior  written  notice to the  Employer.  If the  Employee  shall so
terminate this Agreement, the Employee shall be entitled to be paid only through
the date of such termination.

                                       2
<PAGE>

              b. (1) The Employer, by a majority vote of the Board of Directors,
may terminate  this Agreement at any time for cause,  as defined below,  without
notice to the Employee and with pay only through the date of such termination.

                   (2) Sufficient cause for termination by the Employer shall be
a determination  made in good faith and based upon  reasonable  grounds that the
Employee:  (a) has failed to properly perform his material duties hereunder,  or
has been substantially  absent from employment for material amounts of time; (b)
has engaged in habitual  drunkenness  or abusive  drugs  rendering  the Employee
unable to carry our his duties in a responsible manner; (c) has committed an act
with the intent to defraud or hinder the Employer;  or (d) has been negligent in
the performance of the duties owed by the Employee to the Employer,

                   (3) As soon as may be  practicable  after the  termination of
the Employee by the  Employer for cause,  the Board of Directors of the Employer
shall make an investigation of, and allow the Employee an opportunity to discuss
with the Board of Directors,  the relevant  facts with respect  thereto.  If the
Board of Directors of the Employer  shall  determine  that the Employee has been
terminated without cause, the Employee shall be reinstated in the position which
he held prior to the termination and shall receive any  compensation  accrued or
payable  during  the  period of his  termination.  In such  event,  any  accrued
benefits  shall be  payable  to the  Employee  as if the  Employee  had not been
terminated.

                   (4) Any conduct of the Employee which shall  constitute cause
for  termination  under the terms of subsection b. (2) of this Section 6 and any
breach or evasion of any of the terms of this  Agreement  by either party hereto
will result in immediate  and  irreparable  injury to the injured party and will
authorize  recourse to injunction and/or specific  performance as well as to all
other legal or equitable  remedies to which such  injured  panty may be entitled
hereunder.

              c. If the  Employee  shall die during the term of this  Agreement,
this  Agreement  and  the  Employee's   employment   hereunder  shall  terminate
immediately  upon the  Employee's  death,  provided  that the Employee  shall be
entitled to his salary  hereunder  to the last day of the sixth month  following
the month in which such death occurs.

              d. (1) Notwithstanding anything in this Agreement to the contrary,
the  Employer is hereby  given the option to terminate  this  Agreement  and the
Employee's employment hereunder in the event that the Employee,  during the term
hereof, shall become permanently disabled as defined in subsection d.(2) of this
Section 6 below.  Such option may be exercised by the Employer at any time after
the  Employee  becomes   permanently   disabled  by  giving  written  notice  of
termination to the Employee.  This Agreement and the Employee's employment shall
terminate  one hundred  eighty (180) days after such notice,  provided  that the
Employee shall be entitled to the  compensation as provided in Section 4. hereof
to the last day of the month in which such termination occurs.

         (2)For purposes of this Agreement, the Employee shall be deemed to have
become  permanently  disabled  if,  because of ill  health,  physical  or mental
disability or for other causes beyond his control,  he shall have been unable or
unwilling or shall duties  hereunder on seventy-five  per cent (75%) of the days
during a period of four  (4)consecutive  months,  irrespective of whether or not
such days are consecutive.

                                       3

<PAGE>

         7. Extent of Service: Self-Dealing. The Employee shall devote his full,
normal  working time,  attention and energy to the business of the Employer and,
as  assigned  by the Board of  Directors  of the  Employer,  to the  business of
corporations affiliated with the Employer, and shall not during the term of this
Agreement be engaged in any other  business  activity  which  conflicts with the
Employee's  obligations  under  this  Agreement.  The  foregoing  shall  not  be
construed as preventing  the Employee from making  investments  in businesses or
enterprises provided such investments do not require any services on the part of
the  Employee in the  management,  operation  or affairs of such  businesses  or
enterprises.

         The Employee shall cooperate with, assist and furnish  information upon
request to the  President  or the Board of  Directors  of the Employer or of the
directors or  affiliates  of the Employer and the auditors and legal counsel for
the Employer or its  affiliates.  The provisions of this Section 6 shall survive
termination of this Agreement with respect to matters  arising during the period
of employment of the Employee by the Employer.

         8. Disclosures of Information. The Employee recognizes and acknowledges
that he has and will have  access to  certain  confidential  information  of the
Employer  and  its  affiliates,  such  as  data  accumulation  and  analysis  of
technology,    specifications,    intellectual   property,    applications   for
radiochemical and radiopharmaceutical  products,  lists of clients or customers,
know-how  and other  proprietary  information,  that are  valuable,  special and
unique  assets and property of the Employer  and such  affiliates.  The Employee
will not, after the term of his employment,  disclose, without the prior written
consent or authorization  of the Employer,  any of such information to any firm,
person,  corporation,  association,  enterprise or other entity.  In the event a
third  party  seeks to compel  disclosure  of  confidential  information  by the
Employee by judicial or  administrative  process,  the Employee  shall  promptly
notify the Employer of such occurrence and furnish to the Employer a copy of the
demand,  summons,  subpoena or other process  served upon the Employee to compel
such  disclosure,  and will  permit the  Employer to assume,  at the  Employer's
expense but with the Employee's cooperation, defense of the disclosure demand.

         Upon  termination  of the  Employee's  employment by the Employer,  the
Employee shall neither take or retain any  proprietary  papers,  customer lists,
manuals, files or other documents or copies thereof belonging to the Employer or
any of its affiliates.

           The  provisions of this Section 8, shall survive the  termination  of
this Agreement. In the event of a breach or threatened breach by the Employee of
the  provisions  of this  Section  8,  the  Employer  shall  be  entitled  to an
injunction  restraining the Employee from disclosing,  in whole or in part, such
confidential  information.  Nothing herein shall be construed as prohibiting the
Employer  from  pursuing any other  remedies  available to the Employer for such
breach  or  threatened  breach,  including  the  recovery  of  damages  from the
Employees.

                                        4
<PAGE>

         9.  Vacation.  The Employee  shall be entitled to a vacation of six (6)
weeks  per  year,  plus  customary  local  holidays,  during  the  term  of this
Agreement.  The Employee shall be entitled to receive all  compensation  payable
hereunder in full during the period of any vacation.

         10.  Other  Benefits.  The  Employee  shall be  entitled  to all  other
benefits  contained  in the  approved  Company  benefit  plan(s)  offered to all
employees,  subject  to the  provisions  of such  plan(s).  This  plan  includes
holidays, sick leave and other benefits.

         11.  Notices.  Any notice  required or permitted to be given under this
Agreement  shall be sufficient if in writing and delivered or sent by registered
or certified mail to his last known address, in the case of the Employee,  or to
the principal executives offices of the Company, in the case of the Employer.

         12.  Waiver of Breach.  Any waiver by the  Employer  of a breach of any
provision of this Agreement by the Employee shall not operate or be construed as
a waiver of any subsequent breach by the Employee.

         13.  Assignment.  The rights and obligations of the Employer under this
Agreement shall inure to the benefit of and shall be binding upon the successors
and assigns of the Employer.

         14. Applicable Law. It is the intention of the parties hereto that this
Agreement and the  performance  hereunder and all suits and special  proceedings
here under be construed in accordance with and pursuant to the laws of the State
of Colorado and that in any action,  special proceeding or other proceeding that
may be  brought  arising  out  Of,  in  connection  with  or by  reason  of this
Agreement,  the laws of the  State of  Colorado  shall be  applicable  and shall
govern to the  exclusion  of the law of any other forum,  without  regard to the
jurisdiction in which any action or special proceeding may be instituted.

           15.  Severability.  All agreements and covenants contained herein are
severable,  and in the event any of them,  with the exception of those contained
in Sections ~ and 4 hereof,  shall be held to be invalid by any competent court,
this Agreement  shall be interpreted as if such invalid  agreements or covenants
were not contained herein.

           16. Entire  Agreement.  This Agreement  constitutes  and embodies the
entire  understanding  and agreement of the parties and  supersedes and replaces
all prior  understandings,  agreements  and  negotiations  between the  parties,
provided that nothing herein shall be deemed to restrict or limit the common law
duties of the Employee to the Employer.

         17. Waiver and Modification.  Any waiver, alteration or modification of
any of the provisions of this  Agreement  shall be valid only if made in writing
and signed by the parties  hereto.  Each party  hereto,  from time to time,  may
waive any of his or its rights hereunder without effecting a waiver with respect
to any subsequent occurrences or transactions hereof

                                        5
<PAGE>

         18.  Captions and Paragraph  Heading.  Captions and paragraph  headings
used  herein are for  convenience  only,  are not a part hereof and shall not be
used in construing this Agreement.

IN WITNESS  WHEREOF,  the parties  hereto have  executed  this  Agreement  to be
effective as of the day and year first above written

                                    EMPLOYEE:

                                    /s/ Malcolm H. Benedict
                                    --------------------
                                    Malcolm H Benedict

                                    EMPLOYER
                                    NU-TEC, L.T.D.
Attest:

/s/ Janet L. Davis, Secretary       By: /s/Malcolm H. Benedict
-----------------------------           ----------------------
    Janet L. Davis, Secretary              Malcolm H. Benedict

                                        6

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