Document:

Exhibit 10.49 2001 10K

Exhibit 10.49

LEASE AND LEASE TERMINATION AGREEMENT

This Lease and Lease Termination Agreement ("Agreement") is entered into as
of the 14th day of June 2000, by and between Metropolitan Life
Insurance Company ("Landlord") and Pharmacyclics, Inc. ("Tenant").

Recitals:

A.Landlord's predecessor, New England Mutual Life Insurance Company, and
Tenant entered into (i) that certain Lease Agreement (the "Lease") dated June 17
and 28,1993; (ii) that certain First Amendment to Lease Agreement (the "First
Amendment") dated as of July 22, 1993; and (iii) that certain Second Amendment
to Lease Agreement (the "Second Amendment") dated as of March 1, 1994, all
pertaining to the lease of approximately 32,520 square feet of space located in
the building at 995 Arques Avenue in Sunnyvale, California identified in the
diagram attached hereto as exhibit "A" (the "Premises"). Landlord and Tenant
entered into that certain Third Amendment to Lease Agreement (the "Third
Amendment") dated as of June 14th, 2000. The Lease as amended by the
First Amendment, the Second Amendment, and the Third Amendment is referred to
herein as the "Existing Lease."

B.Landlord and Tenant desire to terminate the Existing Lease and to enter
into a new lease for the Premises as more fully set forth in this Agreement.

Agreement:

Now, therefore, Landlord and Tenant hereby agree as follows:

1.Termination. Effective at 11:59 p.m. P.S.T. on April 30, 2000
(the "Termination Date"), the Existing Lease shall be terminated. Except as
expressly provided in this Agreement, Landlord and Tenant shall have no
obligations to one another under the Existing Lease arising out of circumstances
and events occurring entirely after the Termination Date.

2.New Lease. Landlord hereby leases to Tenant and Tenant hereby
leases from Landlord the Premises (the "New Lease"). Except where inconsistent
with this Agreement, the New Lease shall be on the same terms and conditions as
the Existing Lease. Notwithstanding any provision to the contrary in the
Existing Lease: (i) Tenant shall have no extension or expansion options under
the New Lease; and (ii) Landlord has no and shall in the future have no
obligation to construct any "build-out" or other improvements in or to the
Premises. Tenant hereby accepts the Premises in its "as-is, with all faults"
condition as of the date of this Agreement. Tenant further acknowledges and
agrees that as of the date of this Agreement, Landlord has fully performed its
obligations under the Existing Lease.

  

3.Term. The term of the New Lease shall be for forty-six (46)
months commencing May, 2000, unless sooner terminated.

4.Monthly Installment. The Monthly Installment of rent due each
month under the New Lease shall be as follows:

 

	
 
	
PERIOD
	 	
MONTHLY
AMOUNT
	
 

	
 
	
May 1, 2000 through December 31, 2001
	
 
	
$30,894.00
	
 

	
 
	
January 1-31, 2002
	
 
	
$53,550.77
	
 

	
 
	
February 1, 2002 through January 31,
2003
	
 
	
$69,914.00
	
 

	
 
	
February 1, 2003 through December 31,
2003
	
 
	
$73,410.00
	
 

	
 
	
January 1, 2004 (through January 13,
2004)
	
 
	
$30,784.84
	
 

 

5.Security Deposit. The Security Deposit under the New Lease shall
be Seventy Three Thousand Four Hundred Ten and No/100 Dollars ($73,410.00). At
the time of the execution of this Agreement, Tenant shall deposit with Landlord
the sum of Forty Thousand Eight hundred Ninety and No/100 Dollars ($40,890.00)
toward the Security Deposit and Landlord shall credit Tenant with the Security
Deposit held under the Existing Lease to make up the balance of the Security
Deposit required under the New Lease.

 

 

In witness whereof, the parties have executed this Agreement as of the date
first above written.

 

		
	 	
LANDLORD

METROPOLITAN LIFE INSURANCE COMPANY,

a New York corporation

By:   /s/ Donald K. Devine

Name:   Donald K. Devine

Title:   VICE-PRESIDENT

		
	 	
TENANT

PHARMACYCLICS, INC.,
a Delaware corporation

By:   /s/ Leiv Lea

Name:   Leiv Lea

Title:   V.P. FINANCE & ADMIN., CFOExhibit 10.50 2001 10K

Exhibit 10.50

FIRST AMENDMENT TO NEW LEASE

 

This First Amendment to Lease ("Amendment") is entered
into, and dated for reference purposes, as of April 10, 2001 (the "Execution
Date") by and between METROPOLITAN LIFE INSURANCE COMPANY, a New York
corporation ("Metropolitan"), as Landlord ("Landlord"), and PHARMACYCLICS, INC.,
a Delaware corporation, as Tenant ("Tenant"), with reference to the following
facts ("Recitals"):

A.Landlord and Tenant entered into that certain
written Lease and Lease Termination Agreement, dated as of June 14, 2000 (herein
referred to as the "New Lease"), for the premises described therein as
approximately 32,520 square feet (herein referred to as the "Existing Premises")
of the Building (identified in the New Lease as being located at 995 Arques
Avenue, Sunnyvale, California), all as more particularly described in the New
Lease.

B.Landlord and Tenant desire to provide for the lease
to Tenant of Expansion Space A (defined below) for the term specified herein and
other amendments of the New Lease as more particularly set forth below.

NOW, THEREFORE, in consideration of the foregoing, and of
the mutual covenants set forth herein and of other good and valuable
consideration, the receipt and adequacy of which are hereby acknowledged, the
parties hereto agree as follows:

Section 1.Scope of Amendment; Defined
Terms. Except as expressly provided in this Amendment, the New Lease shall
remain in full force and effect. Should any inconsistency arise between this
Amendment and the New Lease as to the specific matters which are the subject of
this Amendment, the terms and conditions of this Amendment shall control. The
term "New Lease" defined above shall refer to the New Lease as it existed before
giving effect to the modifications set forth in this Amendment and the term
"Lease" as used herein and in the New Lease shall refer to the New Lease as
modified by this Amendment, except as expressly provided in this Amendment. All
capitalized terms used in this Amendment and not defined herein shall have the
meanings set forth in the New Lease unless the context clearly requires
otherwise.

Section 2.Condition Precedent. This
Amendment and the obligations of each party hereunder are expressly subject to
the condition precedent of Landlord successfully entering into and obtaining a
legally binding written amendment or termination of the lease of Expansion Space
A by Mitsubishi Electronics America Inc. ("Mitsubishi"), or otherwise
terminating such lease, in each case, satisfactory in all respects in form and
substance to Landlord, in Landlord's sole discretion, providing for surrender to
Landlord of Expansion Space A (the "Surrender"). Landlord shall give Tenant
written notice of the satisfaction of this condition precedent or of Landlord's
written waiver of this condition precedent. Landlord may give such notice by
tender of delivery to Tenant or its broker of the keys to Expansion Space A or
by any other means permitted by the Lease.

Section 3.Confirmation of
Term.  Landlord and Tenant acknowledge and agree that
notwithstanding any provision of the New Lease to the contrary, as contemplated
by Sections 3 and 4 of the New Lease, January 13, 2004 is the actual expiration
date of the term of the New Lease (herein referred to as the "Expiration Date"
of the "Term").

Section 4.Clarification & Agreement
with respect to Buildings.

(a)Clarification of Address of Building in Which
Existing Premises Is Located. Landlord and Tenant acknowledge and agree as
follows: (i) the Building in which the Existing Premises is located was
identified in the New Lease as having an address of 995 Arques Avenue,
Sunnyvale, California; (ii) that is the address of the Existing Premises, but is
not the only address of the Building; (iii) the Building also houses space with
a current address of 997 Arques Avenue and consequently the Building in fact has
current street addresses of 995 and 997 Arques Avenue, Sunnyvale, California,
which 2 addresses are the more complete and correct identification of the
Building.

(b)Premises in 2 Parts Located in 2 Buildings.
Hereafter, the term "Building" shall mean the respective building in which the
applicable part of the Premises is located, so that for all matters with respect
to the Existing Premises, the term Building shall mean the Building with current
addresses of 995 and 997 Arques Avenue, Sunnyvale, California, and for all
matters with respect to Expansion Space A (defined below) the term Building
shall mean the Building with a current street address of 999 Arques Avenue,
Sunnyvale, California, and all rights, obligations and determinations under the
Lease with respect to a Building shall mean the respective Building in which the
affected part of the Premises is located. Without limiting the generality of the
foregoing, and notwithstanding any other provision of the Lease to the contrary,
in the event of damage or destruction or in the event of a Taking, the effect
thereof and the rights and obligations of the parties shall be determined
separately with respect to each part of the Premises located in a separate
Building, and for example, if such damage, destruction or Taking affects only
one of the Buildings in which the Premises is located, then any and all
termination rights of Landlord or Tenant shall apply, and the respective party
shall be entitled to terminate this Lease only to the extent of the Premises in
the Building in which the casualty or Taking occurred, and the Lease shall
continue in full force and effect to the extent of the other part of the
Premises in the other Building.

Section 5.Lease of Expansion Space
A.

(a)Lease; Definition of Expansion Space A.
Landlord hereby leases to Tenant and Tenant hereby hires from Landlord Expansion
Space A (defined below) upon and subject to all of the terms, covenants and
conditions of the New Lease except as expressly provided herein. "Expansion
Space A" is the entire rentable area of the building located at 999 Arques
Avenue, Sunnyvale, California. Landlord and Tenant hereby agree that Expansion
Space A is conclusively presumed to be 32,256 rentable square feet.

(b)Condition; Commencement Date; Term; Rent; Other
Provisions. Notwithstanding any provision of the New Lease to the contrary,
the following provisions shall govern Expansion Space A:

(1)AS IS Condition; Landlord Work. Except
to the extent of the Landlord Work (defined below), Landlord shall deliver
Expansion Space A to Tenant in its AS IS condition, without any express or
implied representations or warranties of any kind by Landlord, its brokers,
manager or agents, or the employees of any of them regarding Expansion Space A,
and Landlord shall not have any obligation to construct or install any tenant
improvements or alterations or to pay for any such construction or installation,
including, without limitation, any improvement or repair required to comply with
any laws, codes, building codes, rules, orders, ordinances, directions,
regulations and requirements of all governmental authorities, agencies, offices,
departments, bureaus and boards having jurisdiction thereof (collectively,
"Laws"), including without limitation, the Americans with Disabilities Act of
1990 (42 U.S.C. Sec. 12101 et. seq.) and regulations and guidelines promulgated
thereunder, as all of the same may be amended and supplemented from time to time
(collectively referred to herein as the "ADA"). Landlord shall be responsible,
at no cost to Tenant, for the following (the "Landlord Work") when and as
provided below:

(aa) at the time of delivery of Expansion Space A
on the Projected Expansion Space A Commencement Date (as defined below), the
Premises shall be in "broom clean" condition with the personal property and
trade fixtures of the prior lessee removed (except as set forth in Exhibit
A or as otherwise agreed to by Tenant);

(bb) within thirty days after the ESACD, Landlord
shall additionally, as Landlord Work, substantially complete the following: (i)
replacement of any damaged and/or stained ceiling tiles in Expansion Space A;
(ii) professionally shampooing carpeted surfaces in Expansion Space A; and (iii)
touching-up paint on the interior walls of Expansion Space A to the extent
reasonably necessary; and

(cc) Landlord shall additionally, as Landlord
Work, repair the Building Systems and roof membrane serving Expansion Space A to
the extent necessary to put them in good condition if and to the extent that
Tenant, within thirty (30) days after the ESACD (defined below) gives Landlord
written notice setting forth with specificity the nature and extent such
Building Systems and/or roof membrane are not in good condition.

Provided however, Landlord Work shall not apply to, and
Landlord shall have no obligations with respect to any such elements of
Expansion Space A or the Building Systems or roof membrane affected by, or to be
affected by, any alterations Tenant makes or proposes to make to Expansion Space
A.

(2)Delivery; Commencement Date; Term.
Landlord shall tender possession of Expansion Space A to Tenant, in the
condition described in Section 5(b)(1) above, on May 1, 2001 (the "Projected
Expansion Space Commencement Date"). The date on which Landlord in fact tenders
possession shall be the Expansion Space A Commencement Date ("ESACD"), and on
such date Expansion Space A becomes a part of the Premises and Tenant's
obligation commences to pay rent with respect to Expansion Space A. The Term of
this lease of Expansion Space A (the "Space A Term") shall start on the ESACD
and continue until the Expiration Date of the Term of the New Lease.

(3)Delayed or Early Delivery of
Possession. If Landlord shall be unable to give possession of Expansion
Space A on the Projected Expansion Space A Commencement Date by reason of the
following: (i) the portion of the Landlord Work to be completed upon delivery is
not substantially complete, (ii) the holding over or retention of possession of
any tenant, tenants or occupants, or (iii) for any other reason, then Landlord
shall not be subject to any liability for the failure to give possession on said
date. Under such circumstances the ESACD and rent with respect to Expansion
Space A shall not commence until Expansion Space A is made available to Tenant
by Landlord, and no such failure to give possession on the Projected Expansion
Space A Commencement Date shall affect the validity of this Amendment, the New
Lease or the obligations of the Tenant under either. Expansion Space A shall be
deemed to be delivered to Tenant in the event the Landlord Work, if any, is
substantially complete, or if the delay in the availability of the Premises for
occupancy shall be due to any Tenant delay and/or default on the part of Tenant.
In the event of any dispute as to whether the Landlord Work, if any, is
substantially complete, the decision of Landlord's architect shall be final and
binding on the parties. Within thirty (30) days following the occurrence of the
ESACD, Landlord and Tenant shall enter into an agreement (the form of which is
Exhibit C hereto) confirming such date. If Tenant fails to enter into
such agreement, then the ESACD shall be the date designated by Landlord in such
agreement.

(4)Tenant Work Generally. Landlord and
Tenant acknowledge and agree that notwithstanding any provisions of the New
Lease to the contrary: (a) Tenant may desire to do certain alterations,
additions or improvements in connection with this Amendment, and for purposes of
this Amendment any such work may be referred to as Tenant Work; (b) all Tenant
Work, if any, shall be done subject to and in compliance with all conditions and
provisions of this Amendment and of the New Lease with respect to alterations,
improvements or additions in, on, abutting or to the Premises or any part
thereof (herein referred to as "Alterations"). Without limiting the generality
of the foregoing, Tenant shall be responsible for the suitability for the
Tenant's needs and business of the design and function of all Tenant Work and
for its design and construction in compliance with all Laws (as defined above in
this Subsection (c)). In the event that any work by Tenant triggers any upgrades
or modifications of existing improvements to comply with Laws in the Premises,
in the Common Area, or in the "path of travel" to or from the Premises through
the Common Area, Tenant shall be responsible for such upgrades and
modifications, at Tenant's sole cost and expense. Tenant, through its architects
and/or space planners ("Tenant's Architect"), shall prepare all architectural
plans and specifications, and engineering plans and specifications, for the real
property improvements to be constructed by Tenant in the Premises in sufficient
detail to be submitted to Landlord for approval, and to be submitted by Tenant
for governmental approvals and building permits and to serve as the detailed
construction drawings and specifications for the contractor, including all
changes from the As-Is condition of Expansion Space A. Landlord hereby confirms
it has approved Tenant's request to perform Alterations within the scope of the
preliminary design description set forth on Exhibit D hereto.

(c)Monthly Installment of Rent for Expansion Space
A Commencing Upon Expansion Space A Commencement Date. Notwithstanding any
provision of the New Lease to the contrary, in addition to rent payable for the
Existing Premises, Tenant shall pay Monthly Installments of rent for Expansion
Space A, accruing on and after the ESACD and monthly thereafter for the
remaining Term of the Lease as set forth below:

	
Period
from/to
	
Monthly
	
Monthly Rate/rentable square
foot

	
 
	
 
	
 

	
Month 01
	
$0
	
$0

	
Months 02 - 13 
	
$145,152.00
	
$4.50

	
Months 14 - 25 
	
$150,958.08
	
$4.68

	
Months 26 - Expiration Date

	
$156,996.40
	
$4.87

Tenant shall pay Landlord all such
installments at the time and in the manner required for Monthly Installments
pursuant to the New Lease, provided, however, Tenant shall pay Landlord the
first two (2) Monthly Installments for Expansion Space A (a total of Two Hundred
Ninety Thousand Three Hundred Four and No/00 Dollars ($290,304.00)) concurrently
with execution of this Amendment, and Landlord shall credit such payment against
the first and second Monthly Installments due hereunder.

(d)Tenant's Share of Operating Costs &
Taxes. Notwithstanding any provision of the New Lease to the contrary, with
the addition of Expansion Space A to the Premises, Tenant's Pro Rata Share is
conclusively agreed to be 81.1974%, and such increased Tenant's Pro Rata Share
shall apply to all obligations which under the Lease Tenant pays on the basis of
Tenant's Pro Rata Share and which accrue on and after the ESACD.

(e)Parking. Notwithstanding any other
provision of the New Lease to the contrary, on and after the ESACD, with respect
to Expansion Space A, Tenant shall have the right to use, on a non-exclusive
basis, an additional one hundred and thirty-five (135) Parking Spaces.

(f)Suite & Directory Signage.
Notwithstanding any provision of the New Lease to the contrary, on and after the
ESACD, Tenant shall have the right, at Tenant's sole cost, to directory board,
suite signage, and other signage equivalent to the pre-existing signage with
respect to Expansion Space A which Landlord permitted for the prior
occupant.

(g)Increase in Security Deposit.
Notwithstanding any provision of the New Lease to the contrary, in addition to
the cash held by Landlord as a Security Deposit under the New Lease,
concurrently with Tenant's execution of this Amendment, Tenant shall deposit
with Landlord an irrevocable letter of credit in the amount of Four Hundred
Fifty Thousand Dollars ($450,000.00) to be held as part of the Security Deposit
under the Lease in accordance with the provisions of this Section and the Lease
(the "Letter of Credit") so that the total amount of the Security Deposit
hereafter required is Five Hundred Twenty-three Thousand Four Hundred and Ten
Dollars ($523,410.00). The Letter of Credit provided for under this Section
shall be an irrevocable, unconditional "clean" Letter of Credit and require no
documents, and shall be in form, scope and substance and from a banking
institution satisfactory to Landlord, in its sole discretion, provided however,
Landlord pre-approves Union Bank as the issuer of the initial Letter of Credit.
It shall also be in compliance with all applicable laws and regulations,
including, without limitation, applicable regulations of the Comptroller of the
Currency. Said Letter of Credit may have an initial term of no greater than one
(1) year, and shall be extended or reissued in a manner and from a banking
institution satisfactory to Landlord, or replaced by Tenant, in each case at
least thirty (30) days prior to its expiration with another Letter of Credit
which complies with the requirements of this Section, so that in all events the
Letter of Credit shall continue in effect until the date which is forty-five
(45) days after the Termination Date. The Letter of Credit shall be in the form
attached as Exhibit B. Tenant shall pay all expenses, points and/or fees
charged by the issuer or incurred by Tenant in obtaining, transferring or
replacing the Letter of Credit. Upon a proposed sale or other transfer of any
interest (i) of Landlord in the Premises or this Lease, or (ii) in or of
Landlord (including, without limitation, consolidations, mergers or other entity
changes), in all such events Tenant, at its sole cost and expense and upon ten
(10) business days notice, shall, concurrent with Landlord's delivery to the
issuer or Tenant of the then outstanding Letter of Credit, deliver or cause the
issuer to deliver to any such transferees, successors or assigns a replacement
Letter of Credit on identical terms (except for the stated beneficiary) from the
same issuer or another banking institution acceptable to Landlord, in its sole
discretion, naming such transferees, successors or assigns as the new
beneficiary or beneficiaries thereof. It is agreed that in the event (i) Tenant
defaults in the performance or observance of any of the terms, provisions,
covenants and conditions of this Lease, including the payment of Rent or any
other sum due from Tenant with respect to the Lease, or (ii) the Letter of
Credit is not extended or replaced by Tenant in a manner which complies with the
foregoing provisions of this Section, Landlord shall have the right but shall
not be required to, from time to time without prejudice to any other remedy
Landlord may have on account thereof, to present the Letter of Credit for
payment (but any payments or draws with respect to events covered by item (i)
shall be in amounts sufficient to cure the alleged defaults, in Landlord's sole
discretion) and to use, apply or retain the whole or any part of the proceeds to
the extent Landlord could use, apply or retain any other funds deposited with
Landlord as a Security Deposit hereunder, and any amounts so used, applied or
retained shall be replenished by Tenant's payment to Landlord of such amount
within five (5) business days after written demand by Landlord. If Landlord
presents the Letter of Credit for payment, no interest shall be payable to
Tenant on the proceeds. Tenant shall not assign or encumber or attempt to assign
or encumber the Letter of Credit (or the proceeds thereof) held as part of the
Security Deposit, and neither Landlord nor its successors or assigns shall be
bound by any such assignment, encumbrance, attempted assignment or attempted
encumbrance.

Section 6.Amendment of Section 8.C of the
New Lease Re Earthquake Deductible. Notwithstanding any provision of Section
8.C. of the New Lease (as amended by the preceding Third Amendment to Lease
Agreement, dated as of June 14, 2000) to the contrary, the amount which Tenant
shall be required to pay to Landlord as Tenant's Pro Rata Share of the
deductible of any earthquake insurance which Landlord may carry on the Premises
or the Building shall be limited to those amounts during those time periods
specified as follows:

(a) no more than the product of One Dollar times the then-
existing number of rentable square feet of the Premises with respect to each
earthquake occurring when the remaining Term (including any extension thereof)
is 12 months or less;

(b) no more than the product of Two Dollars times the number
of then-existing rentable square feet of the Premises with respect to each
earthquake occurring when the remaining Term (including any extension thereof)
is more than 12 months but not more than 24 months;

(c) no more than the product of Three Dollars times the
number of then-existing rentable square feet of the Premises with respect to
each earthquake occurring when the remaining Term (including any extension
thereof) is more than 24 months but not more than 36 months; and

(d) no more than the product of Four Dollars times the number
of then-existing rentable square feet of the Premises with respect to each
earthquake occurring when the remaining Term (including any extension thereof)
is more than 36 months.

Tenant shall pay the amount of deductible so determined, plus
interest at six percent (6%) per annum amortized on a straight line basis in
equal monthly installments over such remaining Term. Such amount shall be
payable as additional rent without deduction or offset, prior notice or demand,
on the first day of each calendar month starting with the calendar month
immediately following notice from Landlord, but in the event of any termination
of the Lease earlier than the scheduled expiration date of the Term, Tenant
shall pay the remaining unamortized principal balance of such deductible within
ten (10) days after notice from Landlord. Tenant's obligation to pay such
amounts shall survive any termination of the Lease.

Section 7.Time of
Essence.  Without limiting the generality of any other provision
of the New Lease, time is of the essence to each and every term and condition of
this Amendment.

Section 8.Brokers. Notwithstanding any
other provision of the New Lease to the contrary, Tenant represents that except
for Wayne Mascia Associates ("Tenant's Broker"), Tenant has not dealt with any
real estate broker, sales person, or finder in connection with this Amendment,
and no such person initiated or participated in the negotiation of this
Amendment, or showed the Premises to Tenant. Tenant hereby agrees to indemnify,
protect, defend and hold Landlord, Landlord's Parties (as defined in Paragraph
10 of the original Lease Agreement dated June 17 and 28, 1993) and Landlord's
Broker (defined below), harmless from and against any and all liabilities and
claims for commissions and fees arising out of a breach of the foregoing
representation. Landlord agrees to pay any commission to which South Bay
Development Comanay ("Landlord's Broker") is entitled in connection with this
Amendment pursuant to Landlord's written agreement with such broker. Landlord
and Tenant agree that any commission payable to Tenant's Broker shall be
pursuant to a separate agreement between Tenant's Broker and Landlord's Broker
to share the commission paid to Landlord's Broker by Landlord.

Section 9.Attorneys' Fees. Each party
to this Amendment shall bear its own attorneys' fees and costs incurred in
connection with the discussions preceding, negotiations for and documentation of
this Amendment. In the event any party brings any suit or other proceeding with
respect to the subject matter or enforcement of this Amendment or the Lease, the
prevailing party (as determined by the court, agency or other authority before
which such suit or proceeding is commenced) shall, in addition to such other
relief as may be awarded, be entitled to recover attorneys' fees, expenses and
costs of investigation as actually incurred, including court costs, expert
witness fees, costs and expenses of investigation, and all attorneys' fees,
costs and expenses in any such suit or proceeding (including in any action or
participation in or in connection with any case or proceeding under the
Bankruptcy Code, 11 United States Code Sections 101 et seq., or any
successor statutes, in establishing or enforcing the right to indemnification,
in appellate proceedings, or in connection with the enforcement or collection of
any judgment obtained in any such suit or proceeding).

Section 10.Effect of Headings; Recitals:
Exhibits. The titles or headings of the various parts or sections hereof are
intended solely for convenience and are not intended and shall not be deemed to
or in any way be used to modify, explain or place any construction upon any of
the provisions of this Amendment. Any and all Recitals set forth at the
beginning of this Amendment are true and correct and constitute a part of this
Amendment as if they had been set forth as covenants herein. Exhibits,
schedules, plats and riders hereto which are referred to herein are a part of
this Amendment.

Section 11.Entire Agreement; Amendment.
This Amendment taken together with the New Lease, together with all exhibits,
schedules, riders and addenda to each, constitutes the full and complete
agreement and understanding between the parties hereto and shall supersede all
prior communications, representations, understandings or agreements, if any,
whether oral or written, concerning the subject matter contained in this
Amendment and the New Lease, as so amended, and no provision of the Lease as so
amended may be modified, amended, waived or discharged, in whole or in part,
except by a written instrument executed by all of the parties hereto.

Section 12.Authority. Each party
represents and warrants to the other that it has full authority and power to
enter into and perform its obligations under this Amendment, that the person
executing this Amendment is fully empowered to do so, and that no consent or
authorization is necessary from any third party.

Section 13.Counterparts. This Amendment
may be executed in duplicates or counterparts, or both, and such duplicates or
counterparts together shall constitute but one original of the Amendment. Each
duplicate and counterpart shall be equally admissible in evidence, and each
original shall fully bind each party who has executed it.

 

IN WITNESS WHEREOF, the parties hereto have executed this
Amendment as of the date first set forth above.

 

		
	
TENANT

	
PHARMACYCLICS, INC.,

a Delaware corporation

By:   /s/ Richard Miller

Print Name:   RICHARD MILLER

Title:   PRESIDENT & CEO

(Chairman of  Board, President or Vice President)

Date:    4-11-01 

By:   /s/ Leiv Lea

Print Name:   Leiv Lea

Title:   V.P. FINANCE & ADMIN., CFO

(Secretary,  Assistant Secretary, CFO or Assistant Treasurer)

Date:    4-11-01 

		
	
LANDLORD

	
METROPOLITAN LIFE INSURANCE COMPANY,

a New York corporation

By:   /s/ Donald K. Devine

Print Name:   Donald K. Devine

Title:   VICE-PRESIDENT

Date:    4-17-01

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