Document:

Form of Stock Option Agreement (non-US)

 Exhibit 10.42 

AMYRIS BIOTECHNOLOGIES, INC. 

STOCK OPTION AGREEMENT 

(FOR NON-U.S. EMPLOYEES) 

RECITALS 

A.        The Board has adopted the Plan for the purpose of rewarding selected
Employees, non-employee members of the Board or the board of directors of any Parent or Subsidiary and consultants and other independent advisors in the service of the Corporation (or any Parent or Subsidiary). 

B.        This Agreement is executed pursuant to, and is intended to carry out
the purposes of, the Plan in connection with the Corporation’s grant of an option to Optionee. 

C.        All capitalized terms in this Agreement shall have the meaning
assigned to them in the attached Appendix A. 
 NOW, THEREFORE, it is hereby agreed as follows:

 1.        Grant of Option. The Corporation hereby
grants to Optionee, as of the Grant Date, an option to purchase up to the number of Option Shares specified in the Grant Notice. The Option Shares shall be purchasable from time to time during the option term specified in Paragraph 2 at the Exercise
Price and as set forth in the Grant Notice. 
 2.        Option
Term. This option shall have a term of ten (10) years measured from the Grant Date and shall accordingly expire at the close of business on the Expiration Date, unless sooner terminated in accordance with Paragraph 5 or 6. 

3.        Limited Transferability. This option shall be neither
transferable nor assignable by Optionee other than by will or the laws of inheritance following Optionee’s death and may be exercised, during Optionee’s lifetime, only by Optionee. 

4.        Dates of Exercise. This option shall become exercisable
for the Option Shares in one or more installments as specified in the Grant Notice. As the option becomes exercisable for such installments, those installments shall accumulate, and the option shall remain exercisable for the accumulated
installments until the Expiration Date or sooner termination of the option term under Paragraph 5 or 6. 

5.        Cessation of Service. The option term specified in
Paragraph 2 shall terminate (and this option shall cease to be outstanding) prior to the Expiration Date should any of the following provisions become applicable: 

 (a)        Should Optionee cease to
remain in Service for any reason (other than death, Disability or Misconduct) while this option is outstanding, then Optionee shall have a period of three (3) months (commencing with the date of such cessation of Service) during which to
exercise this option, but in no event shall this option be exercisable at any time after the Expiration Date. 

(b)        Should Optionee die while this option is outstanding, then the
personal representative of Optionee’s estate or the person or persons to whom the option is transferred pursuant to Optionee’s will or the laws of inheritance following Optionee’s death shall have the right to exercise this option.
Any such right to exercise this option shall lapse, and this option shall cease to be outstanding, upon the earlier of (i) the expiration of the twelve (12)-month period measured from the date of Optionee’s death or (ii) the
Expiration Date. 
 (c)        Should Optionee cease Service by reason
of Disability while this option is outstanding, then Optionee shall have a period of twelve (12) months (commencing with the date of such cessation of Service) during which to exercise this option. In no event shall this option be exercisable
at any time after the Expiration Date. 
   Note:
Exercise of this option on a date later than three (3) months following cessation of Service due to Disability will result in loss of favorable Incentive Option treatment, unless such Disability constitutes Permanent Disability. In the
event that Incentive Option treatment is not available, this option will be taxed as a Non-Statutory Option upon exercise. 

(d)        During the limited period of post-Service exercisability, this option
may not be exercised in the aggregate for more than the number of Option Shares in which Optionee is, at the time of Optionee’s cessation of Service, vested pursuant to the Vesting Schedule specified in the Grant Notice or the special vesting
acceleration provisions of Paragraph 6. No additional Option Shares shall vest, whether pursuant to the normal Vesting Schedule specified in the Grant Notice or the special vesting acceleration provisions of Paragraph 6, following the
Optionee’s cessation of Service, except to the extent (if any) specifically authorized by the Plan Administrator pursuant to an express written agreement with the Optionee. Upon the expiration of such limited exercise period or (if earlier)
upon the Expiration Date, this option shall terminate and cease to be outstanding for any vested Option Shares for which the option has not been exercised. 

(e)        Should Optionee’s Service be terminated for Misconduct or should
Optionee otherwise engage in Misconduct while this option is outstanding, then this option shall terminate immediately and cease to remain outstanding. 

6.          Change in Control. 

(a)        Should a Change in Control occur during the Optionee’s period of
Service, then the Option Shares at the time subject to this option but not otherwise vested shall automatically vest in full so that this option shall, immediately prior to the effective date of the

  

 2 

 
Change in Control, become exercisable for all of the Option Shares as fully vested shares and may be exercised for any or all of those Option Shares as vested shares. However, the Option Shares
shall not vest on such an accelerated basis if and to the extent: (i) this option is assumed by the successor corporation (or parent thereof) or otherwise continued in full force and effect pursuant to the terms of the Change in Control
transaction and the Corporation’s repurchase rights with respect to the unvested Option Shares are assigned to such successor corporation (or parent thereof) or otherwise continued in effect or (ii) this option is to be replaced with a
cash incentive program of the successor corporation which preserves the spread existing on the unvested Option Shares at the time of the Change in Control (the excess of the Fair Market Value of those Option Shares over the Exercise Price payable
for such shares) and provides for subsequent payout of that spread in accordance with the same Vesting Schedule applicable to those unvested Option Shares as set forth in the Grant Notice or (iii) such accelerated vesting is otherwise precluded
pursuant to the provisions of Paragraph 5(d) above. 

(b)        Immediately following the Change in Control, this option shall
terminate and cease to be outstanding, except to the extent assumed by the successor corporation (or parent thereof) or otherwise continued in full force and effect pursuant to the terms of the Change in Control transaction. 

(c)        If this option is assumed in connection with a Change in Control or
otherwise continued in effect, then this option shall be appropriately adjusted, immediately after such Change in Control, to apply to the number and class of securities which would have been issuable to Optionee in consummation of such Change in
Control had the option been exercised immediately prior to such Change in Control, and appropriate adjustments shall also be made to the Exercise Price, provided the aggregate Exercise Price shall remain the same. To the extent that the actual
holders of the Corporation’s outstanding Common Stock receive cash consideration for their Common Stock in consummation of the Change in Control, the successor corporation may, in connection with the assumption or continuation of this option,
substitute one or more shares of its own common stock with a fair market value equivalent to the cash consideration paid per share of Common Stock in such Change in Control. 

(d)        This Agreement shall not in any way affect the right of the
Corporation to adjust, reclassify, reorganize or otherwise change its capital or business structure or to merge, consolidate, dissolve, liquidate or sell or transfer all or any part of its business or assets. 

7.          Adjustment in Option Shares. Should any
change be made to the Common Stock by reason of any stock split, stock dividend, recapitalization, combination of shares, exchange of shares or other change affecting the outstanding Common Stock as a class without the Corporation’s receipt of
consideration, appropriate adjustments shall be made to (i) the total number and/or class of securities subject to this option and (ii) the Exercise Price in order to reflect such change and thereby preclude a dilution or enlargement of
benefits hereunder. 
  

 3 

8.          Stockholder Rights. The holder of this option
shall not have any stockholder rights with respect to the Option Shares until such person shall have exercised the option, paid the Exercise Price and become the record holder of the purchased shares. 

9.          Manner of Exercising Option. 

(a)      In order to exercise this option with respect to all or any part of the Option
Shares for which this option is at the time exercisable, Optionee (or any other person or persons exercising the option) must take the following actions: 

(i)        Execute and deliver to the Corporation a Purchase
Agreement for the Option Shares for which the option is exercised. 

(ii)        Pay the aggregate Exercise Price for the purchased
shares in one or more of the following forms: 

(A)        cash or check made payable to the Corporation; or

 (B)        a promissory note payable to the
Corporation, but only to the extent authorized by the Plan Administrator in accordance with Paragraph 24. 

Should the Common Stock be registered under Section 12 of the 1934 Act at the time the option is
exercised, then the Exercise Price may also be paid as follows: 

(C)        to the extent the option is exercised for vested
Option Shares, through a special sale and remittance procedure pursuant to which Optionee (or any other person or persons exercising the option) shall concurrently provide irrevocable instructions (a) to a brokerage firm (reasonably
satisfactory to the Corporation for purposes of administering such procedure in compliance with any applicable pre-clearance or pre-notification requirements) to effect the immediate sale of the purchased shares and remit to the Corporation, out of
the sale proceeds available on the settlement date, sufficient funds to cover the aggregate Exercise Price payable for the purchased shares plus all Tax-Related Items, and (b) to the Corporation to deliver the certificates for the purchased
shares directly to such brokerage firm on such settlement date in order to complete the sale. 

Except to the extent the sale and remittance procedure is utilized in connection with the option
exercise, payment of the Exercise Price must accompany the Purchase Agreement delivered to the Corporation in connection with the option exercise. 
  

 4 

(iii)        Furnish to the Corporation appropriate documentation
that the person or persons exercising the option (if other than Optionee) have the right to exercise this option. 

(iv)        Execute and deliver to the Corporation such written
representations as may be requested by the Corporation in order for it to comply with the applicable requirements of applicable securities laws. 

(v)        Make appropriate arrangements with the Corporation
(or Parent or Subsidiary employing or retaining Optionee) for the satisfaction of all Tax-Related Items (as defined below). 

(b)      As soon as practical after the Exercise Date, the Corporation shall issue to or
on behalf of Optionee (or any other person or persons exercising this option) a certificate for the purchased Option Shares, with the appropriate legends affixed thereto. 

(c)      In no event may this option be exercised for any fractional shares. 

10.          Responsibility for Taxes. Regardless of any
action the Corporation or Optionee’s Employer takes with respect to any or all Tax-Related Items, Optionee acknowledges that the ultimate liability for all Tax-Related Items is and remains Optionee’s responsibility and may exceed the
amount actually withheld by the Corporation or the Employer. Optionee further acknowledges that the Corporation and/or the Employer (i) make no representations or undertakings regarding the treatment of any Tax-Related Items in connection with
any aspect of the option, including, but not limited to, the grant, vesting or exercise of the option, the subsequent sale of shares of Option Shares acquired pursuant to such exercise and the receipt of any dividends; and (ii) do not commit to
and are under no obligation to structure the terms of the grant or any aspect of the option to reduce or eliminate Optionee’s liability for Tax-Related Items or achieve any particular tax result. Further, if Optionee has become subject to tax
in more than one jurisdiction between the Grant Date and the date of any relevant taxable event, Optionee acknowledges that the Corporation and/or the Employer (or former employer, as applicable) may be required to withhold or account for
Tax-Related Items in more than one jurisdiction. 
 Prior to the relevant taxable or tax withholding event, as
applicable, Optionee will pay or make adequate arrangements satisfactory to the Corporation and/or the Employer to satisfy all Tax-Related Items. In this regard, Optionee authorizes the Corporation and/or the Employer, or their respective agents, at
their discretion, to satisfy the obligations with regard to all Tax-Related Items by one or a combination of the following: (i) withholding from Optionee’s wages or other cash compensation paid to Optionee by the Corporation and/or the
Employer; or (ii) withholding from proceeds of the sale of shares of Common Stock acquired at exercise of the Option either through a voluntary sale or through a mandatory sale arranged by the Corporation (on Optionee’s behalf pursuant to
this authorization); or (iii) withholding in shares of Common Stock to be issued at exercise of the Option. 

To avoid any negative accounting treatment, the Corporation may withhold or account for Tax-Related Items by considering
applicable minimum statutory withholding amounts or 
  

 5 

 
other applicable withholding rates. If the obligation for Tax-Related Items is satisfied by withholding in shares of Common Stock, for tax purposes, Optionee is deemed to have been issued the
full number of shares of Common Stock subject to the exercised Options, notwithstanding that a number of the shares of Common Stock are held back solely for the purpose of paying the Tax-Related Items due as a result of any aspect of Optionee’s
participation in the Plan. 
 Finally, Optionee shall pay to the Corporation or the Employer any amount of
Tax-Related Items that the Corporation or the Employer may be required to withhold or account for as a result of Optionee’s participation in the Plan that cannot be satisfied by the means previously described. The Corporation may refuse to
issue or deliver the shares or the proceeds of the sale of shares of Common Stock if Optionee fails to comply with Optionee’s obligations in connection with the Tax-Related Items. 

11.          Nature of Grant. In accepting the option,
Optionee acknowledges, understands and agrees that: 
 (a)        the
Plan is established voluntarily by the Corporation, it is discretionary in nature, and may be amended, suspended or terminated by the Corporation at any time; 

(b)        the grant of the option is voluntary and occasional and does not
create any contractual or other right to receive future grants of options, or benefits in lieu of options, even if options have been granted repeatedly in the past; 

(c)        all decisions with respect to future option grants, if any, will be
at the sole discretion of the Corporation; 
 (d)        Optionee is
voluntarily participating in the Plan; 
 (e)        the option and any
Option Shares are extraordinary items that do not constitute compensation of any kind for services of any kind rendered to the Corporation or the Employer, and are outside the scope of Optionee’s employment contract, if any; 

(f)        the option and any Option Shares are not intended to replace any
pension rights or compensation; 
 (g)        the option and Option
Shares are not part of normal or expected compensation or salary for any purposes, including, but not limited to, calculating any severance, resignation, termination, redundancy, dismissal, end of service payments, bonuses, long-service awards,
pension or retirement or welfare benefits or similar payments and in no event should be considered as compensation for, or relating in any way to, past services for the Corporation, the Employer, or any Subsidiary of the Corporation; 

 

 6 

 (h)        the option grant and
Optionee’s participation in the Plan will not be interpreted to form an employment contract or relationship with the Corporation or any Subsidiary of the Corporation; 

(i)        the future value of the shares of Common Stock underlying the option
is unknown and cannot be predicted with certainty; 
 (j)        if the
underlying shares of Common Stock do not increase in value, the option will have no value; 

(k)        if Optionee exercises the option and acquires Option Shares, the
value of such Option Shares may increase or decrease in value, even below the Exercise Price; 

(l)        no claim or entitlement to compensation or damages shall arise from
forfeiture of the option resulting from termination of Optionee’s employment by the Corporation or the Employer (for any reason whatsoever and whether or not in breach of local labor laws) and in consideration of the grant of the option to
which Optionee is otherwise not entitled, Optionee irrevocably agrees never to institute any claim against the Corporation or the Employer, waives his or her ability, if any, to bring any such claim, and releases the Corporation and the Employer
from any such claim; if, notwithstanding the foregoing, any such claim is allowed by a court of competent jurisdiction, then, by participating in the Plan, Optionee shall be deemed irrevocably to have agreed not to pursue such claim and agrees to
execute any and all documents necessary to request dismissal or withdrawal of such claims; 

(m)        if Optionee is an Employee, in the event of termination of
Optionee’s employment (whether or not in breach of local labor laws), Optionee’s right to vest in the option under the Plan, if any, will terminate effective as of the date that Optionee is no longer actively providing Services and will
not be extended by any notice period mandated under local law (e.g., active employment would not include a period of “garden leave” or similar period pursuant to local law); the Board shall have the exclusive discretion to determine
when Optionee is no longer actively providing Services for purposes of Optionee’s option grant; and 

(n)        the option and the benefits under the Plan, if any, will not
automatically transfer to another company in the case of a merger, take-over or transfer of liability. 

12.          No Advice Regarding Grant. The Corporation
is not providing any tax, legal or financial advice, nor is the Corporation making any recommendations regarding Optionee’s participation in the Plan or Optionee’s acquisition or sale of the Option Shares. Optionee is hereby advised to
consult with his or her own personal tax, legal and financial advisors regarding his or her participation in the Plan before taking any action related to the Plan. 

13.          Data Privacy. Optionee hereby explicitly
and unambiguously consents to the collection, use and transfer, in electronic or other form, of Optionee’s personal data as described in this Agreement and any other option grant materials by and among, as applicable,

  

 7 

 
the Employer, the Corporation and its Subsidiaries for the exclusive purpose of implementing, administering and managing Optionee’s participation in the Plan. 

Optionee understands that the Corporation and the Employer may hold certain personal information about Optionee,
including, but not limited to, Optionee’s name, home address and telephone number, date of birth, social insurance number or other identification number, salary, nationality, job title, any shares of stock or directorships held in the
Corporation, details of all options or any other entitlement to shares of stock awarded, canceled, exercised, vested, unvested or outstanding in Optionee’s favor, for the exclusive purpose of implementing, administering and managing the Plan
(“Data”). 
 Optionee understands that Data will be transferred to a stock plan service
provider as may be selected by the Corporation in the future to assist the Corporation with the implementation, administration and management of the Plan. Optionee understands that the recipients of the Data may be located in the United States or
elsewhere, and that the recipient’s country (e.g., the United States) may have different data privacy laws and protections than Optionee’s country. Optionee understands that he or she may request a list with the names and addresses of any
potential recipients of the Data by contacting Optionee’s local human resources representative. Optionee authorizes the Employer, Corporation, any such stock plan service provider and any other possible recipients which may assist the
Corporation (presently or in the future) with implementing, administering and managing the Plan to receive, possess, use, retain and transfer the Data, in electronic or other form, for the purpose of implementing, administering and managing his or
her participation in the Plan. Optionee understands that Data will be held only as long as is necessary to implement, administer and manage Optionee’s participation in the Plan. Optionee understands that he or she may, at any time, view Data,
request additional information about the storage and processing of Data, require any necessary amendments to Data or refuse or withdraw the consents herein, in any case without cost, by contacting in writing his or her local human resources
representative. Optionee understands, however, that refusing or withdrawing his or her consent may affect Optionee’s ability to participate in the Plan. For more information on the consequences of Optionee’s refusal to consent or
withdrawal of consent, Optionee understands that he or she may contact his or her local human resources representative. 

14.        Governing Law. The option grant and the interpretation,
performance and enforcement of this Agreement, the Grant Notice, the Purchase Agreement and any other document related to the Option and/or the Plan are governed by, and subject to, the laws of the State of California, without regard to the conflict
of law provisions, as provided in the Plan. For purposes of litigating any dispute that arises directly or indirectly from the relationship of the parties evidenced by this grant or the Agreement, the Grant Notice, the Purchase Agreement or any
other document related to the Option and/or the Plan, the parties hereby submit to and consent to the exclusive jurisdiction of the State of California and agree that such litigation shall be conducted only in the courts of Alameda County,
California, or the federal courts for the United States for the Northern District of California, and no other courts, where this grant is made and/or to be performed. 

 

 8 

15.          Electronic Delivery. The Corporation may, in
its sole discretion, decide to deliver any documents related to current or future participation in the Plan by electronic means. Optionee hereby consents to receive such documents by electronic delivery and agrees to participate in the Plan through
an on-line or electronic system established and maintained by the Corporation or a third party designated by the Corporation. 

16.          Language. If Optionee has received this
Agreement, or any other document related to the option and/or the Plan translated into a language other than English and if the translated version is different than the English version, the English version will control. 

17.          Severability. The provisions of this
Agreement are severable and if any one or more provisions are determined to be illegal or otherwise unenforceable, in whole or in part, the remaining provisions shall nevertheless be binding and enforceable. 

18.          Appendix B. The option shall be subject to
any special provisions set forth in the attached Appendix B for Optionee’s country of residence, if any. If Optionee relocates to one of the countries included in Appendix B during the life of the option, the special provisions for such country
shall apply to Optionee, to the extent the Corporation determines that the application of such provisions is necessary or advisable in order to comply with local law or facilitate the administration of the Plan. Appendix B constitutes part of this
Agreement. 
 19.          Imposition of Other
Requirements. The Corporation reserves the right to impose other requirements on the option and the Option Shares to the extent the Corporation determines it is necessary or advisable in order to comply with local laws or facilitate the
administration of the Plan, and to require Optionee to sign any additional agreements or undertakings that may be necessary to accomplish the foregoing. 

20.          REPURCHASE RIGHTS. ALL OPTION SHARES ACQUIRED
UPON THE EXERCISE OF THIS OPTION SHALL BE SUBJECT TO CERTAIN RIGHTS OF THE CORPORATION AND ITS ASSIGNS TO REPURCHASE THOSE SHARES IN ACCORDANCE WITH THE TERMS SPECIFIED IN THE PURCHASE AGREEMENT. 

21.          Compliance with Laws and Regulations.

 (a)        The exercise of this option and the issuance of the
Option Shares upon such exercise shall be subject to compliance by the Corporation and Optionee with all applicable requirements of law relating thereto and with all applicable regulations of any stock exchange (or the Nasdaq National Market, if
applicable) on which the Common Stock may be listed for trading at the time of such exercise and issuance. 

(b)        The inability of the Corporation to obtain approval from any
regulatory body having authority deemed by the Corporation to be necessary to the lawful issuance and sale of any Common Stock pursuant to this option shall relieve the Corporation of any liability with respect to the non-issuance or sale of the
Common Stock as to which such 
  

 9 

 
approval shall not have been obtained. The Corporation, however, shall use its best efforts to obtain all such approvals. 

22.          Successors and Assigns. Except to the
extent otherwise provided in Paragraph 6, the provisions of this Agreement shall inure to the benefit of, and be binding upon, the Corporation and its successors and assigns and Optionee, Optionee’s legal representatives, and heirs and legatees
of Optionee’s estate. 

23.          Notices. Any notice required to be given or
delivered to the Corporation under the terms of this Agreement shall be in writing and addressed to the Corporation at its principal corporate offices. Any notice required to be given or delivered to Optionee shall be in writing and addressed to
Optionee at the address indicated below Optionee’s signature line on the Grant Notice. All notices shall be deemed effective upon personal delivery or upon deposit in the post office, postage prepaid and properly addressed to the party to be
notified. 
 24.          Financing. The Plan
Administrator may, in its absolute discretion and without any obligation to do so, permit Optionee to pay the Exercise Price for the purchased Option Shares by delivering a full-recourse promissory note bearing interest at a market rate and secured
by those Option Shares. The payment schedule in effect for any such promissory note shall be established by the Plan Administrator in its sole discretion. 

25.          Construction. This Agreement and the option
evidenced hereby are made and granted pursuant to the Plan and are in all respects limited by and subject to the terms of the Plan. All decisions of the Plan Administrator with respect to any question or issue arising under the Plan or this
Agreement shall be conclusive and binding on all persons having an interest in this option. 

26.          Stockholder Approval. If the Option Shares
covered by this Agreement exceed, as of the Grant Date, the number of shares of Common Stock which may be issued under the Plan as last approved by the stockholders, then this option shall be void with respect to such excess shares, unless
stockholder approval of an amendment sufficiently increasing the number of shares of Common Stock issuable under the Plan is obtained in accordance with the provisions of the Plan. 

27.          Additional Terms Applicable to an Incentive Option
(For U.S. Taxpayers). In the event this option is designated an Incentive Option in the Grant Notice, the following terms and conditions shall also apply to the grant: 

(a)        This option shall cease to qualify for favorable tax treatment as an
Incentive Option if (and to the extent) this option is exercised for one or more Option Shares: (i) more than three (3) months after the date Optionee ceases to be an Employee for any reason other than death or Permanent Disability or
(ii) more than twelve (12) months after the date Optionee ceases to be an Employee by reason of Permanent Disability. 

(b)        This option shall not become exercisable in the calendar year in
which granted if (and to the extent) the aggregate Fair Market Value (determined at the Grant 
  

 10 

 
Date) of the Common Stock for which this option would otherwise first become exercisable in such calendar year would, when added to the aggregate value (determined as of the respective date or
dates of grant) of the Common Stock and any other securities for which one or more other Incentive Options granted to Optionee prior to the Grant Date (whether under the Plan or any other option plan of the Corporation or any Parent or Subsidiary)
first become exercisable during the same calendar year, exceed One Hundred Thousand Dollars ($100,000) in the aggregate. To the extent the exercisability of this option is deferred by reason of the foregoing limitation, the deferred portion shall
become exercisable in the first calendar year or years thereafter in which the One Hundred Thousand Dollar ($100,000) limitation of this Paragraph 27(b) would not be contravened, but such deferral shall in all events end immediately prior to the
effective date of a Change in Control in which this option is not to be assumed or otherwise continued in effect, whereupon the option shall become immediately exercisable as a Non-Statutory Option for the deferred portion of the Option Shares.

 (c)        Should Optionee hold, in addition to this option, one or
more other options to purchase Common Stock which become exercisable for the first time in the same calendar year as this option, then for purposes of the foregoing limitations on the exercisability of such options as Incentive Options, this option
and each of those other options shall be deemed to become first exercisable in that calendar year on the basis of the chronological order in which they were granted, except to the extent otherwise provided under applicable law or regulation.

  

 11 

 APPENDIX A 

The following definitions shall be in effect under the Agreement: 

A.        Agreement shall mean this Stock Option Agreement.

 B.        Board shall mean the Corporation’s
Board of Directors. 
 C.        Change in Control shall
mean a change in ownership or control of the Corporation effected through any of the following transactions: 

(i)        a merger, consolidation or other reorganization
approved by the Corporation’s stockholders, unless securities representing more than fifty percent (50%) of the total combined voting power of the voting securities of the successor corporation are immediately thereafter beneficially
owned, directly or indirectly and in substantially the same proportion, by the persons who beneficially owned the Corporation’s outstanding voting securities immediately prior to such transaction, or 

(ii)        a stockholder-approved sale, transfer or other
disposition of all or substantially all of the Corporation’s assets in liquidation or dissolution of the Corporation, or 

(iii)        the acquisition, directly or indirectly by any
person or related group of persons (other than the Corporation or a person that directly or indirectly controls, is controlled by, or is under common control with, the Corporation), of beneficial ownership (within the meaning of Rule 13d-3 of the
1934 Act) of securities possessing more than fifty percent (50%) of the total combined voting power of the Corporation’s outstanding securities pursuant to a tender or exchange offer made directly to the Corporation’s stockholders.

 In no event shall any public offering of the Corporation’s securities be deemed to constitute a Change
in Control. 
 D.        Code shall mean the U.S.
Internal Revenue Code of 1986, as amended. 
 E.        Common
Stock shall mean the Corporation’s common stock. 

F.        Corporation shall mean Amyris Biotechnologies, Inc., a
California corporation, and any successor corporation to all or substantially all of the assets or voting stock of Amyris Biotechnologies, Inc. which shall by appropriate action assume this option. 

G.        Disability shall mean the inability of Optionee to
engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment and shall be determined by the Plan Administrator on the basis of such medical evidence as the Plan Administrator deems warranted under
the circumstances. Disability shall be 
  

 A-1 

 
deemed to constitute Permanent Disability in the event that such Disability is expected to result in death or has lasted or can be expected to last for a continuous period of tw.elve
(12) months or more. 
 H.        Employee shall
mean an individual who is in the employ of the Corporation (or any Parent or Subsidiary), subject to the control and direction of the employer entity as to both the work to be performed and the manner and method of performance. 

I.        Employer shall mean Optionee’s employer.

 J.        Exercise Date shall mean the date on which
the option shall have been exercised in accordance with Paragraph 9 of the Agreement. 

K.        Exercise Price shall mean the exercise price payable per
Option Share as specified in the Grant Notice. 

L.        Expiration Date shall mean the date on which the option
expires as specified in the Grant Notice. 
 M.        Fair
Market Value per share of Common Stock on any relevant date shall be determined in accordance with the following provisions: 

(i)        If the Common Stock is at the time traded on the
Nasdaq National Market, then the Fair Market Value shall be the closing selling price per share of Common Stock on the date in question, as the price is reported by the National Association of Securities Dealers on the Nasdaq National Market and
published in The Wall Street Journal. If there is no closing selling price for the Common Stock on the date in question, then the Fair Market Value shall be the closing selling price on the last preceding date for which such quotation exists.

 (ii)        If the Common Stock is at the time
listed on any Stock Exchange, then the Fair Market Value shall be the closing selling price per share of Common Stock on the date in question on the Stock Exchange determined by the Plan Administrator to be the primary market for the Common Stock,
as such price is officially quoted in the composite tape of transactions on such exchange and published in The Wall Street Journal. If there is no closing selling price for the Common Stock on the date in question, then the Fair Market Value
shall be the closing selling price on the last preceding date for which such quotation exists. 

(iii)        If the Common Stock is at the time neither listed
on any Stock Exchange nor traded on the Nasdaq National Market, then the Fair Market Value shall be determined by the Plan Administrator after taking into account such factors as the Plan Administrator shall deem appropriate. 

N.        Grant Date shall mean the date of grant of the option as
specified in the Grant Notice. 
  

 A-2 

 O.        Grant
Notice shall mean the Notice of Grant of Stock Option accompanying the Agreement, pursuant to which Optionee has been informed of the basic terms of the option evidenced hereby. 

P.        Incentive Option shall mean an option which satisfies
the requirements of Code Section 422. 

Q.        Misconduct shall mean the commission of any act of
fraud, embezzlement or dishonesty by Optionee, any unauthorized use or disclosure by Optionee of confidential information or trade secrets of the Corporation (or any Parent or Subsidiary), or any other intentional misconduct by Optionee adversely
affecting the business or affairs of the Corporation (or any Parent or Subsidiary) in a material manner. The foregoing definition shall not in any way preclude or restrict the right of the Corporation (or any Parent or Subsidiary) to discharge or
dismiss Optionee or any other person in the Service of the Corporation (or any Parent or Subsidiary) for any other acts or omissions, but such other acts or omissions shall not be deemed, for purposes of the Plan or this Agreement, to constitute
grounds for termination for Misconduct. 
 R.        1934
Act shall mean the U.S. Securities Exchange Act of 1934, as amended. 

S.        Non-Statutory Option shall mean an option not intended
to satisfy the requirements of Code Section 422. 

T.        Option Shares shall mean the number of shares of Common
Stock subject to the option. 
 U.        Optionee shall
mean the person to whom the option is granted as specified in the Grant Notice. 

V.        Parent shall mean any corporation (other than the
Corporation) in an unbroken chain of corporations ending with the Corporation, provided each corporation in the unbroken chain (other than the Corporation) owns, at the time of the determination, stock possessing fifty percent (50%) or more of
the total combined voting power of all classes of stock in one of the other corporations in such chain. 

W.        Plan shall mean the Corporation’s 2005 Stock
Option/Stock Issuance Plan. 
 X.        Plan
Administrator shall mean either the Board or a committee of the Board acting in its capacity as administrator of the Plan. 

Y.        Purchase Agreement shall mean the stock purchase
agreement in substantially the form of Exhibit B to the Grant Notice. 

Z.        Service shall mean the Optionee’s performance of
services for the Corporation (or any Parent or Subsidiary, whether now existing or subsequently established) in 
  

 A-3 

 
the capacity of an Employee, a non-employee member of the board of directors or a consultant or independent advisor. For purposes of this Agreement, Optionee shall be deemed to cease Service
immediately upon the occurrence of either of the following events: (i) Optionee no longer actively performs services in any of the foregoing capacities for the Corporation or any Parent or Subsidiary or (ii) the entity for which Optionee
is performing such services ceases to remain a Parent or Subsidiary of the Corporation, even though the Optionee may subsequently continue to perform services for that entity. Service shall not be deemed to cease during a period of military leave,
sick leave or other personal leave approved by the Corporation; provided, however, that should such leave of absence exceed three (3) months, then for purposes of determining the period within which the Option (if designated as an
Incentive Option in the Grant Notice) may be exercised as such an Incentive Option under the federal tax laws, the Optionee’s Service shall be deemed to cease on the first day immediately following the expiration of such three (3)-month period,
unless Optionee is provided with the right to return to Service following such leave either by statute or by written contract. Except to the extent otherwise required by law or expressly authorized by the Plan Administrator, no Service credit shall
be given for vesting purposes for any period the Optionee is on a leave of absence. 

AA.        Stock Exchange shall mean the American Stock Exchange
or the New York Stock Exchange. 
 BB.        Subsidiary
shall mean any corporation (other than the Corporation) in an unbroken chain of corporations beginning with the Corporation, provided each corporation (other than the last corporation) in the unbroken chain owns, at the time of the determination,
stock possessing fifty percent (50%) or more of the total combined voting power of all classes of stock in one of the other corporations in such chain. 

CC.        Tax-Related Items shall mean any or all income tax,
social insurance, payroll tax, payment on account or other tax-related items related to Optionee’s participation in the Plan and legally applicable to Optionee. 

DD.        Vesting Schedule shall mean the vesting schedule
specified in the Grant Notice pursuant to which the Optionee is to vest in the Option Shares in a series of installments over his or her period of Service. 
  

 A-4 

 APPENDIX B TO 

AMYRIS BIOTECHNOLOGIES, INC. 

STOCK OPTION AGREEMENT 

(FOR NON-U.S. EMPLOYEES) 

Terms and Conditions 

This Appendix B includes additional terms and conditions that govern the options granted to Optionee under the Plan if Optionee resides
in one of the countries listed below. Certain capitalized terms used but not defined in this Appendix B have the meanings set forth in the Plan and/or the Agreement. 

Notifications 

This Appendix B also includes information regarding exchange controls and certain other issues of which Optionee should be aware with
respect to Optionee’s participation in the Plan. The information is based on the securities, exchange control and other laws in effect in the respective countries as of December 2009. Such laws are often complex and change frequently. As a
result, the Corporation strongly recommends that Optionee not rely on the information in this Appendix B as the only source of information relating to the consequences of Optionee’s participation in the Plan because the information may be out
of date at the time that Optionee exercises the Option or sells Option Shares acquired under the Plan. 
 In addition, the
information contained herein is general in nature and may not apply to Optionee’s particular situation and the Corporation is not in a position to assure Optionee of any particular result. Accordingly, Optionee is advised to seek appropriate
professional advice as to how the relevant laws in Optionee’s country may apply to Optionee’s situation. 
 Finally,
if Optionee is a citizen or resident of a country other than the one in which Optionee is currently working, the information contained herein may not be applicable to Optionee. 

BRAZIL 

Terms and Conditions 

Compliance with Law. By accepting the option, Optionee acknowledges his or her agreement to
comply with applicable Brazilian laws and to pay any and all applicable taxes associated with the exercise of the option, the receipt of any dividends, and the sale of Option Shares acquired under the Plan.Form of Stock Purchase Agreement

 Exhibit 10.43 

AMYRIS BIOTECHNOLOGIES, INC.  

STOCK PURCHASE AGREEMENT 

AGREEMENT made this              day of
                                    ,
             by and between Amyris Biotechnologies, Inc., a California corporation, and
                                         
   , Optionee under the Corporation’s 2005 Stock Option/Stock Issuance Plan. 
 All
capitalized terms in this Agreement shall have the meaning assigned to them in this Agreement or in the attached Appendix. 
  

	 	 A.
	 EXERCISE OF OPTION 

1.        Exercise.   Optionee hereby purchases
             shares of Common Stock (the “Purchased Shares”) pursuant to that certain option (the “Option”) granted Optionee on
                                ,
             (the “Grant Date”) to purchase up to
                     shares of Common Stock (the “Option Shares”) under the Plan at the exercise price of
$                     per share (the “Exercise Price”). 

2.        Payment. Concurrently with the delivery of this
Agreement to the Corporation, Optionee shall pay the Exercise Price for the Purchased Shares in accordance with the provisions of the Option Agreement and shall deliver whatever additional documents may be required by the Option Agreement as a
condition for exercise, together with a duly-executed blank Assignment Separate from Certificate (in the form attached hereto as Exhibit I) with respect to the Purchased Shares. 

3.        Stockholder Rights.   Until such time as the
Corporation exercises the Repurchase Right or the First Refusal Right, Optionee (or any successor in interest) shall have all the rights of a stockholder (including voting, dividend and liquidation rights) with respect to the Purchased Shares,
subject, however, to the transfer restrictions of Articles B and C. 
  

	 	 B.
	 SECURITIES LAW COMPLIANCE 

1.        Restricted Securities.   The Purchased Shares
have not been registered under the 1933 Act and are being issued to Optionee in reliance upon the exemption from such registration provided by SEC Rule 701 for stock issuances under compensatory benefit plans such as the Plan. Optionee hereby
confirms that Optionee has been informed that the Purchased Shares are restricted securities under the 1933 Act and may not be resold or transferred unless the Purchased Shares are first registered under the Federal securities laws or unless an
exemption from such registration is available. Accordingly, Optionee hereby acknowledges that Optionee is acquiring the Purchased Shares for investment purposes only and not with a view to resale and is prepared to hold the Purchased Shares for an
indefinite period and that Optionee is aware that SEC Rule 144 issued under the 1933 Act which exempts certain resales of unrestricted securities is not presently available to exempt the resale of the Purchased Shares from the registration
requirements of the 1933 Act. 

 2.       Restrictions on Disposition of
Purchased Shares.   Optionee shall make no disposition of the Purchased Shares (other than a Permitted Transfer) unless and until there is compliance with all of the following requirements: 

(i)        Optionee shall have provided the Corporation with a
written summary of the terms and conditions of the proposed disposition. 

(ii)       Optionee shall have complied with all requirements of this
Agreement applicable to the disposition of the Purchased Shares. 

(iii)      Optionee shall have provided the Corporation with written
assurances, in form and substance satisfactory to the Corporation, that (a) the proposed disposition does not require registration of the Purchased Shares under the 1933 Act or (b) all appropriate action necessary for compliance with the
registration requirements of the 1933 Act or any exemption from registration available under the 1933 Act (including Rule 144) has been taken. 

The Corporation shall not be required (i) to transfer on its books any Purchased Shares which have been sold
or transferred in violation of the provisions of this Agreement or (ii) to treat as the owner of the Purchased Shares, or otherwise to accord voting, dividend or liquidation rights to, any transferee to whom the Purchased Shares have been
transferred in contravention of this Agreement. 
 3.      Restrictive
Legends.   The stock certificates for the Purchased Shares shall be endorsed with one or more of the following restrictive legends: 

“The shares represented by this certificate have not been registered under the Securities Act of
1933. The shares may not be sold or offered for sale in the absence of (a) an effective registration statement for the shares under such Act, (b) a ‘no action’ letter of the Securities and Exchange Commission with respect to such
sale or offer or (c) satisfactory assurances to the Corporation that registration under such Act is not required with respect to such sale or offer.” 

“The shares represented by this certificate are subject to certain repurchase rights and rights of
first refusal granted to the Corporation and accordingly may not be sold, assigned, transferred, encumbered, or in any manner disposed of except in conformity with the terms of a written agreement dated
                    , 20      between the Corporation and the registered holder of the shares (or the predecessor
in interest to the shares). A copy of such agreement is maintained at the Corporation’s principal corporate offices.” 
  

 2 

	 	 C.
	 TRANSFER RESTRICTIONS 

1.      Restriction on Transfer.   Except for any Permitted
Transfer, Optionee shall not transfer, assign, encumber or otherwise dispose of any of the Purchased Shares which are subject to the Repurchase Right. In addition, Purchased Shares which are released from the Repurchase Right shall not be
transferred, assigned, encumbered or otherwise disposed of in contravention of the First Refusal Right or the Market Stand-Off. 

2.      Transferee Obligations.   Each person (other than the
Corporation) to whom the Purchased Shares are transferred by means of a Permitted Transfer must, as a condition precedent to the validity of such transfer, acknowledge in writing to the Corporation that such person is bound by the provisions of this
Agreement and that the transferred shares are subject to (i) the Repurchase Right, (ii) the First Refusal Right and (iii) the Market Stand-Off, to the same extent such shares would be so subject if retained by Optionee. 

3.      Market Stand-Off. 

(a)        In connection with any underwritten public offering by the
Corporation of its equity securities pursuant to an effective registration statement filed under the 1933 Act, including the Corporation’s initial public offering, Owner shall not sell, make any short sale of, loan, hypothecate, pledge, grant
any option for the purchase of, or otherwise dispose or transfer for value or otherwise agree to engage in any of the foregoing transactions with respect to, any Purchased Shares without the prior written consent of the Corporation or its
underwriters. Such restriction (the “Market Stand-Off”) shall be in effect for such period of time from and after the effective date of the final prospectus for the offering as may be requested by the Corporation or such underwriters. In
no event, however, shall such period exceed one hundred eighty (180) days, and the Market Stand-Off shall in no event be applicable to any underwritten public offering effected more than two (2) years after the effective date of the
Corporation’s initial public offering. 
 (b)        Owner shall
be subject to the Market Stand-Off provided and only if the officers and directors of the Corporation are also subject to similar restrictions. 

(c)        Any new, substituted or additional securities which are by reason of
any Recapitalization or Reorganization distributed with respect to the Purchased Shares shall be immediately subject to the Market Stand-Off, to the same extent the Purchased Shares are at such time covered by such provisions. 

(d)        In order to enforce the Market Stand-Off, the Corporation may impose
stop-transfer instructions with respect to the Purchased Shares until the end of the applicable stand-off period. 
  

 3 

	 	 D.
	 REPURCHASE RIGHT 

1.      Grant.   The Corporation is hereby granted the right (the
“Repurchase Right”), exercisable at any time during the sixty (60)-day period following the date Optionee ceases for any reason to remain in Service or (if later) during the sixty (60)-day period following the execution date of this
Agreement, to repurchase at the Repurchase Price any or all of the Purchased Shares in which Optionee is not, at the time of his or her cessation of Service, vested in accordance with the Vesting Schedule applicable to those shares or the special
vesting acceleration provisions of Paragraph D.6 of this Agreement (such shares to be hereinafter referred to as the “Unvested Shares”). 

2.      Exercise of the Repurchase Right.   The Repurchase Right
shall be exercisable by written notice delivered to each Owner of the Unvested Shares prior to the expiration of the sixty (60)-day exercise period. The notice shall indicate the number of Unvested Shares to be repurchased, the Repurchase Price to
be paid per share and the date on which the repurchase is to be effected, such date to be not more than thirty (30) days after the date of such notice. The certificates representing the Unvested Shares to be repurchased shall be delivered to
the Corporation on the closing date specified for the repurchase. Concurrently with the receipt of such stock certificates, the Corporation shall pay to Owner, in cash or cash equivalents (including the cancellation of any purchase-money
indebtedness), an amount equal to the Repurchase Price for the Unvested Shares which are to be repurchased from Owner. 

3.      Termination of the Repurchase Right.   The Repurchase
Right shall terminate with respect to any Unvested Shares for which it is not timely exercised under Paragraph D.2. In addition, the Repurchase Right shall terminate and cease to be exercisable with respect to any and all Purchased Shares in which
Optionee vests in accordance with the Vesting Schedule. All Purchased Shares as to which the Repurchase Right lapses shall, however, remain subject to (i) the First Refusal Right and (ii) the Market Stand-Off. 

4.      Aggregate Vesting Limitation.   If the Option is exercised
in more than one increment so that Optionee is a party to one or more other Stock Purchase Agreements (the “Prior Purchase Agreements”) which are executed prior to the date of this Agreement, then the total number of Purchased Shares as to
which Optionee shall be deemed to have a fully-vested interest under this Agreement and all Prior Purchase Agreements shall not exceed in the aggregate the number of Purchased Shares in which Optionee would otherwise at the time be vested, in
accordance with the Vesting Schedule, had all the Purchased Shares (including those acquired under the Prior Purchase Agreements) been acquired exclusively under this Agreement. 

5.      Recapitalization.   Any new, substituted or additional
securities or other property (including cash paid other than as a regular cash dividend) which is by reason of any Recapitalization distributed with respect to the Purchased Shares shall be immediately subject to the Repurchase Right and any escrow
requirements hereunder, but only to the extent the Purchased Shares are at the time covered by such right or escrow requirements. Appropriate adjustments to reflect such distribution shall be made to the number and/or class of Purchased

  

 4 

 
Shares subject to this Agreement and to the Repurchase Price per share to be paid upon the exercise of the Repurchase Right in order to reflect the effect of any such Recapitalization upon the
Corporation’s capital structure; provided, however, that the aggregate Repurchase Price shall remain the same. 

6.      Change in Control. 

(a)        The Repurchase Right shall automatically terminate in its entirety,
and all the Purchased Shares shall vest in full, immediately prior to the consummation of any Change in Control, except to the extent the Repurchase Right is to be assigned to the successor entity in such Change in Control or otherwise continued in
full force and effect pursuant to the terms of the Change in Control transaction. 

(b)        To the extent the Repurchase Right remains in effect following a
Change in Control, such right shall apply to any new securities or other property (including any cash payments) received in exchange for the Purchased Shares in consummation of the Change in Control, but only to the extent the Purchased Shares are
at the time covered by such right. Appropriate adjustments shall be made to the Repurchase Price per share payable upon exercise of the Repurchase Right to reflect the effect (if any) of the Change in Control upon the Corporation’s capital
structure; provided, however, that the aggregate Repurchase Price shall remain the same. The new securities or other property (including any cash payments) issued or distributed with respect to the Purchased Shares in consummation of the
Change in Control shall be immediately deposited in escrow with the Corporation (or the successor entity) and shall not be released from escrow until Optionee vests in such securities or other property in accordance with the same Vesting Schedule in
effect for the Purchased Shares. 
  

	 	 E.
	 RIGHT OF FIRST REFUSAL 

1.      Grant.   The Corporation is hereby granted the right of
first refusal (the “First Refusal Right”), exercisable in connection with any proposed transfer of the Purchased Shares in which Optionee has vested in accordance with the provisions of Article D. For purposes of this Article E, the term
“transfer” shall include any sale, assignment, pledge, encumbrance or other disposition of the Purchased Shares intended to be made by Owner, but shall not include any Permitted Transfer. 

2.      Notice of Intended Disposition.   In the event any Owner
of Purchased Shares in which Optionee has vested desires to accept a bona fide third-party offer for the transfer of any or all of such shares (the Purchased Shares subject to such offer to be hereinafter referred to as the “Target
Shares”), Owner shall promptly (i) deliver to the Corporation written notice (the “Disposition Notice”) of the terms of the offer, including the purchase price and the identity of the third-party offeror, and (ii) provide
satisfactory proof that the disposition of the Target Shares to such third-party offeror would not be in contravention of the provisions set forth in Articles B and C. 
  

 5 

 3.      Exercise of the First Refusal
Right.   The Corporation shall, for a period of twenty-five (25) days following receipt of the Disposition Notice, have the right to repurchase any or all of the Target Shares subject to the Disposition Notice upon the same
terms as those specified therein or upon such other terms (not materially different from those specified in the Disposition Notice) to which Owner consents. Such right shall be exercisable by delivery of written notice (the “Exercise
Notice”) to Owner prior to the expiration of the twenty-five (25)-day exercise period. If such right is exercised with respect to all the Target Shares, then the Corporation shall effect the repurchase of such shares, including payment of the
purchase price, not more than five (5) business days after delivery of the Exercise Notice; and at such time the certificates representing the Target Shares shall be delivered to the Corporation. 

Should the purchase price specified in the Disposition Notice be payable in property other than cash or evidences of
indebtedness, the Corporation shall have the right to pay the purchase price in the form of cash equal in amount to the value of such property. If Owner and the Corporation cannot agree on such cash value within ten (10) days after the
Corporation’s receipt of the Disposition Notice, the valuation shall be made by an appraiser of recognized standing selected by Owner and the Corporation or, if they cannot agree on an appraiser within twenty (20) days after the
Corporation’s receipt of the Disposition Notice, each shall select an appraiser of recognized standing and the two (2) appraisers shall designate a third appraiser of recognized standing, whose appraisal shall be determinative of such
value. The cost of such appraisal shall be shared equally by Owner and the Corporation. The closing shall then be held on the later of (i) the fifth (5th) business day following delivery of the Exercise Notice or (ii) the fifth
(5th) business day after such valuation shall have been made. 

4.      Non-Exercise of the First Refusal Right.   In the event
the Exercise Notice is not given to Owner prior to the expiration of the twenty-five (25)-day exercise period, Owner shall have a period of thirty (30) days thereafter in which to sell or otherwise dispose of the Target Shares to the
third-party offeror identified in the Disposition Notice upon terms (including the purchase price) no more favorable to such third-party offeror than those specified in the Disposition Notice; provided, however, that any such sale or disposition
must not be effected in contravention of the provisions of Articles B and C. The third-party offeror shall acquire the Target Shares subject to the First Refusal Right and the provisions and restrictions of Article B and Paragraph C.3, and any
subsequent disposition of the acquired shares must be effected in compliance with the terms and conditions of such First Refusal Right and the provisions and restrictions of Article B and Paragraph C.3. In the event Owner does not effect such sale
or disposition of the Target Shares within the specified thirty (30)-day period, the First Refusal Right shall continue to be applicable to any subsequent disposition of the Target Shares by Owner until such right lapses. 

5.      Partial Exercise of the First Refusal Right.   In the
event the Corporation makes a timely exercise of the First Refusal Right with respect to a portion, but not all, of the Target Shares specified in the Disposition Notice, Owner shall have the option, exercisable by written notice to the Corporation
delivered within five (5) business days after Owner’s receipt of the Exercise Notice, to effect the sale of the Target Shares pursuant to either of the following alternatives: 

 

 6 

 (i)        sale or
other disposition of all the Target Shares to the third-party offeror identified in the Disposition Notice, but in full compliance with the requirements of Paragraph E.4, as if the Corporation did not exercise the First Refusal Right; or 

(ii)        sale to the Corporation of the portion of the Target
Shares which the Corporation has elected to purchase, such sale to be effected in substantial conformity with the provisions of Paragraph E.3. The First Refusal Right shall continue to be applicable to any subsequent disposition of the remaining
Target Shares until such right lapses. 
 Owner’s failure to deliver timely notification to the
Corporation shall be deemed to be an election by Owner to sell the Target Shares pursuant to alternative (i) above. 

6.      Recapitalization/Reorganization. 

(a)        Any new, substituted or additional securities or other property which
is by reason of any Recapitalization distributed with respect to the Purchased Shares shall be immediately subject to the First Refusal Right, but only to the extent the Purchased Shares are at the time covered by such right. 

(b)        In the event of a Reorganization, the First Refusal Right shall
remain in full force and effect and shall apply to the new capital stock or other property received in exchange for the Purchased Shares in consummation of the Reorganization, but only to the extent the Purchased Shares are at the time covered by
such right. 
 7.      Lapse.   The First Refusal Right
shall lapse upon the earliest to occur of (i) the first date on which shares of the Common Stock are held of record by more than five hundred (500) persons, (ii) a determination made by the Board that a public market exists for the
outstanding shares of Common Stock or (iii) a firm commitment underwritten public offering, pursuant to an effective registration statement under the 1933 Act, covering the offer and sale of the Common Stock in the aggregate amount of at least
twenty million dollars ($20,000,000). However, the Market Stand-Off shall continue to remain in full force and effect following the lapse of the First Refusal Right. 
  

	 	 F.
	 SPECIAL TAX ELECTION 

The acquisition of the Purchased Shares may result in adverse tax consequences which may be avoided or mitigated by
filing an election under Code Section 83(b). Such election must be filed within thirty (30) days after the date of this Agreement. A description of the tax consequences applicable to the acquisition of the Purchased Shares and the form for
making the Code Section 83(b) election are set forth in Exhibit II. OPTIONEE SHOULD CONSULT WITH HIS OR HER TAX ADVISOR TO DETERMINE THE TAX CONSEQUENCES OF ACQUIRING THE PURCHASED SHARES AND THE ADVANTAGES AND DISADVANTAGES OF FILING THE
CODE SECTION 83(b) ELECTION. OPTIONEE ACKNOWLEDGES THAT IT IS OPTIONEE’S SOLE 
  

 7 

 
RESPONSIBILITY, AND NOT THE CORPORATION’S, TO FILE A TIMELY ELECTION UNDER CODE SECTION 83(b), EVEN IF OPTIONEE REQUESTS THE CORPORATION OR ITS REPRESENTATIVES TO MAKE THIS FILING ON HIS OR
HER BEHALF. 
  

	 	 G.
	 GENERAL PROVISIONS 

1.      Assignment.   The Corporation may assign the Repurchase
Right and/or the First Refusal Right to any person or entity selected by the Board, including (without limitation) one or more stockholders of the Corporation. 

2.      At Will Employment.   Nothing in this Agreement or in the
Plan shall confer upon Optionee any right to continue in Service for any period of specific duration or interfere with or otherwise restrict in any way the rights of the Corporation (or any Parent or Subsidiary employing or retaining Optionee) or of
Optionee, which rights are hereby expressly reserved by each, to terminate Optionee’s Service at any time for any reason, with or without cause. 

3.      Notices.   Any notice required to be given under this
Agreement shall be in writing and shall be deemed effective upon personal delivery or upon deposit in the U.S. mail, registered or certified, postage prepaid and properly addressed to the party entitled to such notice at the address indicated below
such party’s signature line on this Agreement or at such other address as such party may designate by ten (10) days advance written notice under this paragraph to all other parties to this Agreement. 

4.      No Waiver.   The failure of the Corporation in any
instance to exercise the Repurchase Right or the First Refusal Right shall not constitute a waiver of any other repurchase rights and/or rights of first refusal that may subsequently arise under the provisions of this Agreement or any other
agreement between the Corporation and Optionee. No waiver of any breach or condition of this Agreement shall be deemed to be a waiver of any other or subsequent breach or condition, whether of like or different nature. 

5.      Cancellation of Shares.   If the Corporation shall make
available, at the time and place and in the amount and form provided in this Agreement, the consideration for the Purchased Shares to be repurchased in accordance with the provisions of this Agreement, then from and after such time, the person from
whom such shares are to be repurchased shall no longer have any rights as a holder of such shares (other than the right to receive payment of such consideration in accordance with this Agreement). Such shares shall be deemed purchased in accordance
with the applicable provisions hereof, and the Corporation shall be deemed the owner and holder of such shares, whether or not the certificates therefor have been delivered as required by this Agreement. 

 

 8 

	 	 H.
	 MISCELLANEOUS PROVISIONS 

1.      Optionee Undertaking.   Optionee hereby agrees to take
whatever additional action and execute whatever additional documents the Corporation may deem necessary or advisable in order to carry out or effect one or more of the obligations or restrictions imposed on either Optionee or the Purchased Shares
pursuant to the provisions of this Agreement. 
 2.      Agreement is
Entire Contract.   This Agreement constitutes the entire contract between the parties hereto with regard to the subject matter hereof. This Agreement is made pursuant to the provisions of the Plan and shall in all respects be
construed in conformity with the terms of the Plan. 
 3.      Governing
Law.   This Agreement shall be governed by, and construed in accordance with, the laws of the State of California without resort to that State’s conflict-of-laws rules. 

4.      Counterparts.   This Agreement may be executed in
counterparts, each of which shall be deemed to be an original, but all of which together shall constitute one and the same instrument. 

5.      Successors and Assigns.   The provisions of this Agreement
shall inure to the benefit of, and be binding upon, the Corporation and its successors and assigns and upon Optionee, Optionee’s permitted assigns and the legal representatives, heirs and legatees of Optionee’s estate, whether or not any
such person shall have become a party to this Agreement and have agreed in writing to join herein and be bound by the terms hereof. 
  

 9 

 IN WITNESS WHEREOF, the parties have executed this Agreement on the
day and year first indicated above. 
  

			
	 AMYRIS BIOTECHNOLOGIES, INC.

		
	 By:
	 	 
		
	 Name:
	 	 
		
	 Title:
	 	 
		
	 Address:
	 	 
		
		 	 
		
		 	 
		 	        , OPTIONEE
		
	 Address:
	 	 
		
		 	 
		 	

  

 10 

 SPOUSAL ACKNOWLEDGMENT 

The undersigned spouse of Optionee has read and hereby approves the foregoing Stock Purchase Agreement. In consideration
of the Corporation’s granting Optionee the right to acquire the Purchased Shares in accordance with the terms of such Agreement, the undersigned hereby agrees to be irrevocably bound by all the terms of such Agreement, including (without
limitation) the right of the Corporation (or its assigns) to purchase any Purchased Shares in which Optionee is not vested at time of his or her cessation of Service. 

 

			
		
		 	 
		 	 OPTIONEE’S SPOUSE

		
	 Address:
	 	 
		
		 	 
		 	

 EXHIBIT I 

ASSIGNMENT SEPARATE FROM CERTIFICATE 

FOR VALUE RECEIVED
                             hereby sell(s), assign(s) and transfer(s) unto Amyris Biotechnologies,
Inc. (the “Corporation”),                      (            )
shares of the Common Stock of the Corporation standing in his or her name on the books of the Corporation represented by Certificate No.
                     herewith and do(es) hereby irrevocably constitute and appoint
                             Attorney to transfer the said stock on the books of the Corporation with
full power of substitution in the premises. 
 Dated:
                             

Signature
                                         
                    

Instruction: Please do not fill in any blanks other than the signature line. Please sign exactly as you would like your name to
appear on the issued stock certificate. The purpose of this assignment is to enable the Corporation to exercise the Repurchase Right without requiring additional signatures on the part of Optionee. 

 EXHIBIT II 

FEDERAL INCOME TAX CONSEQUENCES AND 

SECTION 83(b) TAX ELECTION 

I.        Federal Income Tax Consequences and Section 83(b) Election
For Exercise of Non-Statutory Option. If the Purchased Shares are acquired pursuant to the exercise of a Non-Statutory Option, as specified in the Grant Notice, then under Code Section 83, the excess of the Fair Market Value of the
Purchased Shares on the date any forfeiture restrictions applicable to such shares lapse over the Exercise Price paid for those shares will be reportable as ordinary income on the lapse date. For this purpose, the term “forfeiture
restrictions” includes the right of the Corporation to repurchase the Purchased Shares pursuant to the Repurchase Right. However, Optionee may elect under Code Section 83(b) to be taxed at the time the Purchased Shares are acquired, rather
than when and as such Purchased Shares cease to be subject to such forfeiture restrictions. Such election must be filed with the Internal Revenue Service within thirty (30) days after the date of the Agreement. Even if the Fair Market Value of
the Purchased Shares on the date of the Agreement equals the Exercise Price paid (and thus no tax is payable), the election must be made to avoid adverse tax consequences in the future. The form for making this election is attached as part of this
exhibit. FAILURE TO MAKE THIS FILING WITHIN THE APPLICABLE THIRTY (30)-DAY PERIOD WILL RESULT IN THE RECOGNITION OF ORDINARY INCOME BY OPTIONEE AS THE FORFEITURE RESTRICTIONS LAPSE. 

II.        Federal Income Tax Consequences and Conditional
Section 83(b) Election For Exercise of Incentive Option. If the Purchased Shares are acquired pursuant to the exercise of an Incentive Option, as specified in the Grant Notice, then the following tax principles shall be applicable to
the Purchased Shares: 
 (i)        For regular tax
purposes, no taxable income will be recognized at the time the Option is exercised. 

(ii)       The excess of (a) the Fair Market Value of the
Purchased Shares on the date the Option is exercised or (if later) on the date any forfeiture restrictions applicable to the Purchased Shares lapse over (b) the Exercise Price paid for the Purchased Shares will be includible in Optionee’s
taxable income for alternative minimum tax purposes. 

(iii)      If Optionee makes a disqualifying disposition of the Purchased
Shares, then Optionee will recognize ordinary income in the year of such disposition equal in amount to the excess of (a) the Fair Market Value of the Purchased Shares on the date the Option is exercised or (if later) on the date any forfeiture
restrictions applicable to the Purchased Shares lapse over (b) the Exercise Price paid for the Purchased Shares. Any additional gain recognized upon the disqualifying disposition will be either short-term or long-term capital gain depending
upon the period for which the Purchased Shares are held prior to the disposition. 

 (iv)        For
purposes of the foregoing, the term “forfeiture restrictions” will include the right of the Corporation to repurchase the Purchased Shares pursuant to the Repurchase Right. The term “disqualifying disposition” means any sale or
other disposition1 of the Purchased Shares within two
(2) years after the Grant Date or within one (1) year after the exercise date of the Option. 

(v)        The Code Section 83(b) election will be
effective in limiting the Optionee’s alternative minimum taxable income to the excess of the Fair Market Value of the Purchased Shares at the time the Option is exercised over the Exercise Price paid for those shares. 

Page 2 of the attached form for making the election should be filed with any election made in connection with the
exercise of an Incentive Option. 
  
  

1
 Generally, a disposition of shares purchased under an Incentive Option includes any transfer of legal title, including a transfer by sale, exchange or gift, but does not include a
transfer to the Optionee’s spouse, a transfer into joint ownership with right of survivorship if Optionee remains one of the joint owners, a pledge, a transfer by bequest or inheritance or certain tax-free exchanges permitted under the Code.

  

 2 

 SECTION 83(b) ELECTION 

This statement is being made under Section 83(b) of the Internal Revenue Code, pursuant to Treas. Reg.
Section 1.83-2. 
  

	 (1)
	 The taxpayer who performed the services is: 

Name: 

Address: 

Taxpayer Ident. No.: 
  

	 (2)
	 The property with respect to which the election is being made is
                     shares of the common stock of Amyris Biotechnologies, Inc. 

 

	 (3)
	 The property was issued on
                    ,             . 

 

	 (4)
	 The taxable year in which the election is being made is the calendar year
            . 

  

	 (5)
	 The property is subject to a repurchase right pursuant to which the issuer has the right to acquire the property at the lower of the purchase price
paid per share or the fair market value per share, if for any reason taxpayer’s service with the issuer terminates. The issuer’s repurchase right will lapse in a series of annual and monthly installments over a five (5)-year period ending
on                     , 20__. 

  

	 (6)
	 The fair market value at the time of transfer (determined without regard to any restriction other than a restriction which by its terms will never
lapse) is $                     per share. 

  

	 (7)
	 The amount paid for such property is
$                     per share. 

  

	 (8)
	 A copy of this statement was furnished to Amyris Biotechnologies, Inc. for whom taxpayer rendered the services underlying the transfer of property.

  

	 (9)
	 This statement is executed on
                            ,
            . 

  

					
			
	  	 		 	  
	 Spouse (if any)
	 		 	 Taxpayer

 This
election must be filed with the Internal Revenue Service Center with which taxpayer files his or her Federal income tax returns and must be made within thirty (30) days after the execution date of the Stock Purchase Agreement. This filing
should be made by registered or certified mail, return receipt requested. Optionee must retain two (2) copies of the completed form for filing with his or her Federal and state tax returns for the current tax year and an additional copy for his
or her records. 

 The property described in the above Section 83(b) election is
comprised of shares of common stock acquired pursuant to the exercise of an incentive stock option under Section 422 of the Internal Revenue Code (the “Code”). Accordingly, the purpose of this election is to have the alternative
minimum taxable income attributable to the purchased shares measured by the amount by which the fair market value of such shares at the time of their transfer to the Taxpayer exceeds the purchase price paid for the shares. In the absence of this
election, such alternative minimum taxable income would be measured by the spread between the fair market value of the purchased shares and the purchase price which exists on the various lapse dates in effect for the forfeiture restrictions
applicable to such shares. 
 THIS PAGE 2 IS TO BE ATTACHED TO ANY SECTION 83(b) ELECTION FILED IN CONNECTION WITH THE
EXERCISE OF AN INCENTIVE STOCK OPTION UNDER THE FEDERAL TAX LAWS. 
  

 2 

 APPENDIX 

The following definitions shall be in effect under the Agreement: 

A.        Agreement shall mean this Stock Purchase Agreement.

 B.        Board shall mean the Corporation’s
Board of Directors. 
 C.        Change in Control shall
mean a change in ownership or control of the Corporation effected through any of the following transactions: 

  (i)        a merger, consolidation or other
reorganization approved by the Corporation’s stockholders, unless securities representing more than fifty percent (50%) of the total combined voting power of the voting securities of the successor corporation are immediately thereafter
beneficially owned, directly or indirectly and in substantially the same proportion, by the persons who beneficially owned the Corporation’s outstanding voting securities immediately prior to such transaction, or 

  (ii)      a stockholder-approved sale, transfer or other
disposition of all or substantially all of the Corporation’s assets in liquidation or dissolution of the Corporation, or 

  (iii)     the acquisition, directly or indirectly by any person or
related group of persons (other than the Corporation or a person that directly or indirectly controls, is controlled by, or is under common control with, the Corporation), of beneficial ownership (within the meaning of Rule 13d-3 of the 1934 Act) of
securities possessing more than fifty percent (50%) of the total combined voting power of the Corporation’s outstanding securities pursuant to a tender or exchange offer made directly to the Corporation’s stockholders. 

In no event shall any public offering of the Corporation’s securities be deemed to constitute a Change in Control.

 D.        Code shall mean the Internal Revenue Code of
1986, as amended. 
 E.        Common Stock shall mean
the Corporation’s common stock. 

F.        Corporation shall mean Amyris Biotechnologies, Inc., a
California corporation, and any successor corporation to all or substantially all of the assets or voting stock of Amyris Biotechnologies, Inc. which shall by appropriate action adopt the Plan. 

G.        Disposition Notice shall have the meaning assigned to
such term in Paragraph E.2. 
  

 A-1 

 H.      Exercise Price shall
have the meaning assigned to such term in Paragraph A.1. 

I.        Fair Market Value per share of Common Stock on any
relevant date shall be determined in accordance with the following provisions: 

(i)        If the Common Stock is at the time traded on the
Nasdaq National Market, then the Fair Market Value shall be the closing selling price per share of Common Stock on the date in question, as such price is reported by the National Association of Securities Dealers on the Nasdaq National Market and
published in The Wall Street Journal. If there is no closing selling price for the Common Stock on the date in question, then the Fair Market Value shall be the closing selling price on the last preceding date for which such quotation exists.

 (ii)      If the Common Stock is at the time listed on any
Stock Exchange, then the Fair Market Value shall be the closing selling price per share of Common Stock on the date in question on the Stock Exchange determined by the Plan Administrator to be the primary market for the Common Stock, as such price
is officially quoted in the composite tape of transactions on such exchange and published in The Wall Street Journal. If there is no closing selling price for the Common Stock on the date in question, then the Fair Market Value shall be the
closing selling price on the last preceding date for which such quotation exists. 

(iii)     If the Common Stock is at the time neither listed on any Stock
Exchange nor traded on the Nasdaq National Market, then the Fair Market Value shall be determined by the Plan Administrator after taking into account such factors as the Plan Administrator shall deem appropriate. 

J.        First Refusal Right shall mean the right granted to the
Corporation in accordance with Article E. 
 K.        Grant
Date shall have the meaning assigned to such term in Paragraph A.1. 

L.        Grant Notice shall mean the Notice of Grant of Stock
Option pursuant to which Optionee has been informed of the basic terms of the Option. 

M.       Incentive Option shall mean an option which satisfies the
requirements of Code Section 422. 
 N.        Market
Stand-Off shall mean the market stand-off restriction specified in Paragraph C.3. 

O.        1933 Act shall mean the Securities Act of 1933, as
amended. 
 P.        1934 Act shall mean the Securities
Exchange Act of 1934, as amended. 
  

 A-2 

 Q.        Non-Statutory
Option shall mean an option not intended to satisfy the requirements of Code Section 422. 

R.        Option shall have the meaning assigned to such term in
Paragraph A.1. 
 S.        Option Agreement shall mean
all agreements and other documents evidencing the Option. 

T.        Optionee shall mean the person to whom the Option is
granted under the Plan. 
 U.        Owner shall mean
Optionee and all subsequent holders of the Purchased Shares who derive their chain of ownership through a Permitted Transfer from Optionee. 

V.        Parent shall mean any corporation (other than the
Corporation) in an unbroken chain of corporations ending with the Corporation, provided each corporation in the unbroken chain (other than the Corporation) owns, at the time of the determination, stock possessing fifty percent (50%) or more of
the total combined voting power of all classes of stock in one of the other corporations in such chain. 

W.        Permitted Transfer shall mean (i) a gratuitous
transfer of the Purchased Shares, provided and only if Optionee obtains the Corporation’s prior written consent to such transfer, (ii) a transfer of title to the Purchased Shares effected pursuant to Optionee’s will or the laws of
inheritance following Optionee’s death or (iii) a transfer to the Corporation in pledge as security for any purchase-money indebtedness incurred by Optionee in connection with the acquisition of the Purchased Shares. 

X.        Plan shall mean the Corporation’s 2005 Stock
Option/Stock Issuance Plan. 
 Y.        Plan
Administrator shall mean either the Board or a committee of the Board acting in its capacity as administrator of the Plan. 

Z.        Prior Purchase Agreement shall have the meaning assigned
to such term in Paragraph D.4. 
 AA.     Purchased Shares shall have
the meaning assigned to such term in Paragraph A.1. 

BB.     Recapitalization shall mean any stock split, stock dividend,
recapitalization, combination of shares, exchange of shares or other change affecting the Corporation’s outstanding Common Stock as a class without the Corporation’s receipt of consideration. 

 

 A-3 

CC.        Reorganization shall mean any of the following
transactions: 
     (i)       a merger
or consolidation in which the Corporation is not the surviving entity, 

    (ii)      a sale, transfer or other disposition of
all or substantially all of the Corporation’s assets, 

    (iii)     a reverse merger in which the Corporation is
the surviving entity but in which the Corporation’s outstanding voting securities are transferred in whole or in part to a person or persons different from the persons holding those securities immediately prior to the merger, or 

    (iv)      any transaction effected primarily to
change the state in which the Corporation is incorporated or to create a holding company structure. 

DD.      Repurchase Price shall mean the lower of (i) the
Exercise Price or (ii) the Fair Market Value per share of Common Stock on the date of Optionee’s cessation of Service. 

EE.       Repurchase Right shall mean the right granted to the
Corporation in accordance with Article D. 
 FF.       SEC
shall mean the Securities and Exchange Commission. 

GG.      Service shall mean the Optionee’s performance of services for
the Corporation (or any Parent or Subsidiary, whether now existing or subsequently established) in the capacity of an Employee, a non-employee member of the board of directors or a consultant or independent advisor. For purposes of this Agreement,
Optionee shall be deemed to cease Service immediately upon the occurrence of the either of the following events: (i) Optionee no longer performs services in any of the foregoing capacities for the Corporation or any Parent or Subsidiary or
(ii) the entity for which Optionee is performing such services ceases to remain a Parent or Subsidiary of the Corporation, even though the Optionee may subsequently continue to perform services for that entity. Service shall not be deemed to
cease during a period of military leave, sick leave or other personal leave approved by the Corporation. However, except to the extent otherwise required by law or expressly authorized by the Plan Administrator, no Service credit shall be given for
vesting purposes for any period the Optionee is on a leave of absence. 

HH.      Subsidiary shall mean any corporation (other than the Corporation)
in an unbroken chain of corporations beginning with the Corporation, provided each corporation (other than the last corporation) in the unbroken chain owns, at the time of the determination, stock possessing fifty percent (50%) or more of the
total combined voting power of all classes of stock in one of the other corporations in such chain. 

II.         Target Shares shall have the meaning assigned to
such term in Paragraph E.2. 
  

 A-4 

 JJ.         Unvested
Shares shall have the meaning assigned to such term in Paragraph D.1. 

KK.      Vesting Schedule shall mean the vesting schedule specified in the
Grant Notice pursuant to which the Optionee is to vest in the Option Shares in a series of installments over his or her period of Service. 
  

 A-5

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00172-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00172-of-00352.parquet"}]]