Document:

2001 Stock Incentive Plan

 Exhibit 10.1 
 CAMBRIDGE HEART, INC. 
 2001 STOCK INCENTIVE PLAN 

1. Purpose  
 The purpose
of this 2001 Stock Incentive Plan (the “Plan”) of Cambridge Heart, Inc., a Delaware corporation (the “Company”), is to advance the interests of the Company’s stockholders by enhancing the Company’s ability to attract,
retain and motivate persons who make (or are expected to make) important contributions to the Company by providing such persons with equity ownership opportunities and performance-based incentives and thereby better aligning the interests of such
persons with those of the Company’s stockholders. Except where the context otherwise requires, the term “Company” shall include any of the Company’s present or future parent or subsidiary corporations as defined in Sections
424(e) or (f) of the Internal Revenue Code of 1986, as amended, and any regulations promulgated thereunder (the “Code”) and any other business venture (including, without limitation, joint venture or limited liability company) in
which the Company has a significant interest, as determined by the Board of Directors of the Company (the “Board”). 
 2.
Eligibility  
 All of the Company’s employees, officers, directors, consultants and advisors (and any individuals who
have accepted an offer for employment) are eligible to be granted options or restricted stock awards (each, an “Award”) under the Plan. Each person who has been granted an Award under the Plan shall be deemed a “Participant”.

 3. Administration and Delegation  
 (a) Administration by Board of Directors. The Plan will be administered by the Board. The Board shall have authority to grant Awards and to adopt, amend and repeal such administrative rules,
guidelines and practices relating to the Plan as it shall deem advisable. The Board may correct any defect, supply any omission or reconcile any inconsistency in the Plan or any Award in the manner and to the extent it shall deem expedient to carry
the Plan into effect and it shall be the sole and final judge of such expediency. All decisions by the Board shall be made in the Board’s sole discretion and shall be final and binding on all persons having or claiming any interest in the Plan
or in any Award. No director or person acting pursuant to the authority delegated by the Board shall be liable for any action or determination relating to or under the Plan made in good faith. 

(b) Appointment of Committees. To the extent permitted by applicable law, the Board may delegate any or all of its powers under
the Plan to one or more committees or subcommittees of the Board (a “Committee”). All references in the Plan to the “Board” shall mean the Board or a Committee of the Board to the extent that the Board’s powers or authority
under the Plan have been delegated to such Committee. 
 4. Stock Available for Awards  

(a) Number of Shares. Subject to adjustment under Section 7, Awards may be made under the Plan for up to 8,250,000 shares of
common stock, $.001 par value per share, of the Company (the “Common Stock”). If any Award expires or is terminated, surrendered or canceled without having been fully exercised or is forfeited in whole or in part (including as the result
of shares of Common Stock subject to such Award being repurchased by the Company at the original issuance price pursuant to a contractual repurchase right) or results in any Common Stock not being issued, the unused Common Stock covered by such
Award shall again be available for the grant of Awards under the Plan, subject, however, in the case of Incentive Stock Options (as hereinafter defined), to any limitations under the Code. Shares issued under the Plan may consist in whole or in part
of authorized but unissued shares or treasury shares. 
 (b) Per-Participant Limit. Subject to adjustment under
Section 7, the maximum number of shares of Common Stock with respect to which Awards may be granted to any Participant under the Plan shall be 900,000 per calendar year. The per-Participant limit described in this Section 4(b) shall
be construed and applied consistently with Section 162(m) of the Code (“Section 162(m)”). 

 5. Stock Options  
 (a) General. The Board may grant options to purchase Common Stock (each, an “Option”) and determine the number of shares of Common Stock to be covered by each Option, the exercise price
of each Option and the conditions and limitations applicable to the exercise of each Option, including conditions relating to applicable federal or state securities laws, as it considers necessary or advisable. An Option which is not intended to be
an Incentive Stock Option (as hereinafter defined) shall be designated a “Nonstatutory Stock Option”. 
 (b)
Incentive Stock Options. An Option that the Board intends to be an “incentive stock option” as defined in Section 422 of the Code (an “Incentive Stock Option”) shall only be granted to employees of the Company and shall
be subject to and shall be construed consistently with the requirements of Section 422 of the Code. The Company shall have no liability to a Participant, or any other party, if an Option (or any part thereof) which is intended to be an
Incentive Stock Option is not an Incentive Stock Option. 
 (c) Exercise Price. The Board shall establish the exercise
price at the time each Option is granted and specify it in the applicable option agreement, provided, however, that the exercise price shall be not less than 100% of the Fair Market Value (as hereinafter defined) of the Common Stock at the time the
Option is granted. 
 (d) Duration of Options. Each Option shall be exercisable at such times and subject to such terms
and conditions as the Board may specify in the applicable option agreement, provided, however, that no Option will be granted for a term in excess of 10 years. 
 (e) Exercise of Option. Options may be exercised by delivery to the Company of a written notice of exercise signed by the proper person or by any other form of notice (including electronic notice)
approved by the Board together with payment in full as specified in Section 5(f) for the number of shares for which the Option is exercised. 
 (f) Payment Upon Exercise. Common Stock purchased upon the exercise of an Option granted under the Plan shall be paid for as follows: 

(1) in cash or by check, payable to the order of the Company; 

(2) except as the Board may, in its sole discretion, otherwise provide in an option agreement, by (i) delivery of an
irrevocable and unconditional undertaking by a creditworthy broker to deliver promptly to the Company sufficient funds to pay the exercise price and any required tax withholding or (ii) delivery by the Participant to the Company of a copy of
irrevocable and unconditional instructions to a creditworthy broker to deliver promptly to the Company cash or a check sufficient to pay the exercise price and any required tax withholding; 

(3) to the extent permitted by the Board, in its sole discretion, when the Common Stock is registered under the Securities
Exchange Act of 1934 (the “Exchange Act”), by delivery of shares of Common Stock owned by the Participant valued at their fair market value as determined by (or in a manner approved by) the Board in good faith (“Fair Market
Value”), provided (i) such method of payment is then permitted under applicable law and (ii) such Common Stock, if acquired directly from the Company was owned by the Participant at least six months prior to such delivery; 

(4) to the extent permitted by the Board, in its sole discretion by (i) delivery of a promissory note of the
Participant to the Company on terms determined by the Board, or (ii) payment of such other lawful consideration as the Board may determine; or 
 (5) by any combination of the above permitted forms of payment. 

 (g) Substitute Options. In connection with a merger or consolidation of an entity
with the Company or the acquisition by the Company of property or stock of an entity, the Board may grant Options in substitution for any options or other stock or stock-based awards granted by such entity or an affiliate thereof. Substitute Options
may be granted on such terms as the Board deems appropriate in the circumstances, notwithstanding any limitations on Options contained in the other sections of this Section 5 or in Section 2. 

6. Restricted Stock.  

(a) Grants. The Board may grant Awards entitling recipients to acquire shares of Common Stock, subject to the right of the Company
to repurchase all or part of such shares at their issue price or other stated or formula price (or to require forfeiture of such shares if issued at no cost) from the recipient in the event that conditions specified by the Board in the applicable
Award are not satisfied prior to the end of the applicable restriction period or periods established by the Board for such Award (each, a “Restricted Stock Award”). 
 (b) Share Limit. Subject to adjustment under Section 7, the maximum aggregate number of shares of Common Stock with respect to which Restricted Stock Awards may be granted under the Plan shall
be 1,500,000. 
 (c) Terms and Conditions. The Board shall determine the terms and conditions of any such Restricted
Stock Award, including the conditions for repurchase (or forfeiture) and the issue price, if any. 
 (d) Stock
Certificates. Any stock certificates issued in respect of a Restricted Stock Award shall be registered in the name of the Participant and, unless otherwise determined by the Board, deposited by the Participant, together with a stock power
endorsed in blank, with the Company (or its designee). At the expiration of the applicable restriction periods, the Company (or such designee) shall deliver the certificates no longer subject to such restrictions to the Participant or if the
Participant has died, to the beneficiary designated, in a manner determined by the Board, by a Participant to receive amounts due or exercise rights of the Participant in the event of the Participant’s death (the “Designated
Beneficiary”). In the absence of an effective designation by a Participant, Designated Beneficiary shall mean the Participant’s estate. 
 7. Adjustments for Changes in Common Stock and Certain Other Events  

(a) Changes in Capitalization. In the event of any stock split, reverse stock split, stock dividend, recapitalization, combination
of shares, reclassification of shares, spin-off or other similar change in capitalization or event, or any distribution to holders of Common Stock other than a normal cash dividend, (i) the number and class of securities available under this
Plan, (ii) the per-Participant limit set forth in Section 4(b), (iii) the number and class of securities and exercise price per share subject to each outstanding Option, and (iv) the repurchase price per share subject to each
outstanding Restricted Stock Award shall be appropriately adjusted by the Company (or substituted Awards may be made, if applicable) to the extent the Board shall determine, in good faith, that such an adjustment (or substitution) is necessary and
appropriate. If this Section 7(a) applies and Section 7(c) also applies to any event, Section 7(c) shall be applicable to such event, and this Section 7(a) shall not be applicable. 

(b) Liquidation or Dissolution. In the event of a proposed liquidation or dissolution of the Company, the Board shall upon written
notice to the Participants provide that all then unexercised Options will (i) become exercisable in full as of a specified time at least 10 business days prior to the effective date of such liquidation or dissolution and (ii) terminate
effective upon such liquidation or dissolution, except to the extent exercised before such effective date. The Board may specify the effect of a liquidation or dissolution on any Restricted Stock Award or other Award granted under the Plan at the
time of the grant of such Award. 
 (c) Reorganization Events  

(1) Definition. A “Reorganization Event” shall mean: (a) any merger or consolidation of the Company
with or into another entity as a result of which all of the Common Stock of the Company is converted into or exchanged for the right to receive cash, securities or other property or (b) any exchange of all of the Common Stock of the Company for
cash, securities or other property pursuant to a share exchange transaction. 

 (2) Consequences of a Reorganization Event on Options. Upon the
occurrence of a Reorganization Event, or the execution by the Company of any agreement with respect to a Reorganization Event, the Board shall provide that all outstanding Options shall be assumed, or equivalent options shall be substituted, by the
acquiring or succeeding corporation (or an affiliate thereof). For purposes hereof, an Option shall be considered to be assumed if, following consummation of the Reorganization Event, the Option confers the right to purchase, for each share of
Common Stock subject to the Option immediately prior to the consummation of the Reorganization Event, the consideration (whether cash, securities or other property) received as a result of the Reorganization Event by holders of Common Stock for each
share of Common Stock held immediately prior to the consummation of the Reorganization Event (and if holders were offered a choice of consideration, the type of consideration chosen by the holders of a majority of the outstanding shares of Common
Stock); provided, however, that if the consideration received as a result of the Reorganization Event is not solely common stock of the acquiring or succeeding corporation (or an affiliate thereof), the Company may, with the consent of the acquiring
or succeeding corporation, provide for the consideration to be received upon the exercise of Options to consist solely of common stock of the acquiring or succeeding corporation (or an affiliate thereof) equivalent in fair market value to the per
share consideration received by holders of outstanding shares of Common Stock as a result of the Reorganization Event. 
 Notwithstanding the foregoing, if the acquiring or succeeding corporation (or an affiliate thereof) does not agree to assume, or substitute for, such Options, then the Board shall, upon written notice to
the Participants, provide that all then unexercised Options will become exercisable in full as of a specified time prior to the Reorganization Event and will terminate immediately prior to the consummation of such Reorganization Event, except to the
extent exercised by the Participants before the consummation of such Reorganization Event; provided, however, that in the event of a Reorganization Event under the terms of which holders of Common Stock will receive upon consummation thereof a cash
payment for each share of Common Stock surrendered pursuant to such Reorganization Event (the “Acquisition Price”), then the Board may instead provide that all outstanding Options shall terminate upon consummation of such Reorganization
Event and that each Participant shall receive, in exchange therefor, a cash payment equal to the amount (if any) by which (A) the Acquisition Price multiplied by the number of shares of Common Stock subject to such outstanding Options (whether
or not then exercisable), exceeds (B) the aggregate exercise price of such Options. 
 (3) Consequences
of a Reorganization Event on Restricted Stock Awards. Upon the occurrence of a Reorganization Event, the repurchase and other rights of the Company under each outstanding Restricted Stock Award shall inure to the benefit of the Company’s
successor and shall apply to the cash, securities or other property which the Common Stock was converted into or exchanged for pursuant to such Reorganization Event in the same manner and to the same extent as they applied to the Common Stock
subject to such Restricted Stock Award. 
 8. General Provisions Applicable to Awards  

(a) Transferability of Awards. Except as the Board may otherwise determine or provide in an Award, Awards shall not be sold,
assigned, transferred, pledged or otherwise encumbered by the person to whom they are granted, either voluntarily or by operation of law, except by will or the laws of descent and distribution, and, during the life of the Participant, shall be
exercisable only by the Participant. References to a Participant, to the extent relevant in the context, shall include references to authorized transferees. 
 (b) Documentation. Each Award shall be evidenced in such form (written, electronic or otherwise) as the Board shall determine. Each Award may contain terms and conditions in addition to those set
forth in the Plan. 
 (c) Board Discretion. Except as otherwise provided by the Plan, each Award may be made alone or in
addition or in relation to any other Award. The terms of each Award need not be identical, and the Board need not treat Participants uniformly. 

 (d) Termination of Status. The Board shall determine the effect on an Award of the
disability, death, retirement, authorized leave of absence or other change in the employment or other status of a Participant and the extent to which, and the period during which, the Participant, the Participant’s legal representative,
conservator, guardian or Designated Beneficiary may exercise rights under the Award. 
 (e) Withholding. Each Participant
shall pay to the Company, or make provision satisfactory to the Board for payment of, any taxes required by law to be withheld in connection with Awards to such Participant no later than the date of the event creating the tax liability. Except as
the Board may otherwise provide in an Award, when the Common Stock is registered under the Exchange Act, Participants may satisfy such tax obligations in whole or in part by delivery of shares of Common Stock, including shares retained from the
Award creating the tax obligation, valued at their Fair Market Value; provided, however, that the total tax withholding where stock is being used to satisfy such tax obligations cannot exceed the Company’s minimum statutory withholding
obligations (based on minimum statutory withholding rates for federal and state tax purposes, including payroll taxes, that are applicable to such supplemental taxable income). The Company may, to the extent permitted by law, deduct any such tax
obligations from any payment of any kind otherwise due to a Participant. 
 (f) Conditions on Delivery of Stock. The
Company will not be obligated to deliver any shares of Common Stock pursuant to the Plan or to remove restrictions from shares previously delivered under the Plan until (i) all conditions of the Award have been met or removed to the
satisfaction of the Company, (ii) in the opinion of the Company’s counsel, all other legal matters in connection with the issuance and delivery of such shares have been satisfied, including any applicable securities laws and any applicable
stock exchange or stock market rules and regulations, and (iii) the Participant has executed and delivered to the Company such representations or agreements as the Company may consider appropriate to satisfy the requirements of any applicable
laws, rules or regulations. 
 (g) Acceleration. The Board may at any time provide that any Award shall become
immediately exercisable in full or in part, free of some or all restrictions or conditions, or otherwise realizable in full or in part, as the case may be. 
 9. Miscellaneous  
 (a) No Right To Employment or Other Status. No
person shall have any claim or right to be granted an Award, and the grant of an Award shall not be construed as giving a Participant the right to continued employment or any other relationship with the Company. The Company expressly reserves the
right at any time to dismiss or otherwise terminate its relationship with a Participant free from any liability or claim under the Plan, except as expressly provided in the applicable Award. 

(b) No Rights As Stockholder. Subject to the provisions of the applicable Award, no Participant or Designated Beneficiary shall
have any rights as a stockholder with respect to any shares of Common Stock to be distributed with respect to an Award until becoming the record holder of such shares. Notwithstanding the foregoing, in the event the Company effects a split of the
Common Stock by means of a stock dividend and the exercise price of and the number of shares subject to such Option are adjusted as of the date of the distribution of the dividend (rather than as of the record date for such dividend), then an
optionee who exercises an Option between the record date and the distribution date for such stock dividend shall be entitled to receive, on the distribution date, the stock dividend with respect to the shares of Common Stock acquired upon such
Option exercise, notwithstanding the fact that such shares were not outstanding as of the close of business on the record date for such stock dividend. 
 (c) Effective Date and Term of Plan. The Plan shall become effective on the date on which it is adopted by the Board, but no Award granted to a Participant that is intended to comply with
Section 162(m) shall become exercisable, vested or realizable, as applicable to such Award, unless and until the Plan has been approved by the Company’s stockholders to the extent stockholder approval is required by Section 162(m) in
the manner required under Section 162(m) (including the vote required under Section 162(m)). No Awards shall be granted under the Plan after December 31, 2012. 
 (d) Amendment of Plan. The Board may amend, suspend or terminate the Plan or any portion thereof at any time, provided that to the extent required by Section 162(m), no Award granted to a
Participant that is intended to 

 
comply with Section 162(m) after the date of such amendment shall become exercisable, realizable or vested, as applicable to such Award, unless and until such amendment shall have been
approved by the Company’s stockholders as required by Section 162(m) (including the vote required under Section 162(m)). 
 (e) Governing Law. The provisions of the Plan and all Awards made hereunder shall be governed by and interpreted in accordance with the laws of the State of Delaware, without regard to any
applicable conflicts of law. 
 Approved by Board of Directors February 9, 2001 
 Approved by Shareholders May 31, 2001 
 Amended by Board of Directors April 23, 2003

 Amendment Approved by Shareholders June 16, 2003 
 Amended by Board of Directors April 26, 2005 
 Amendment Approved by Shareholders
June 10, 2005 
 Amended by Board of Directors April 23, 2007 
 Approved by Shareholders June 19, 2007 
 Amended by Board of Directors March 22, 2011

 Amended by Board of Directors March 5, 2012Letter Agreement

 Exhibit 10.1 

 
 

 
 May 11, 2012 
 The Procter & Gamble Distributing Company LLC 
 Two Procter & Gamble Plaza

 Cincinnati, Ohio 45202 Attention: J.D. Weedman 
 Vice President, Global Business Development 
  

	Cc:	The Procter & Gamble Company 

	 	One Procter & Gamble Plaza 

	 	Cincinnati, OH 45202 

	 	Attention: Associate General Counsel, Director 

	 	Health & Well-Being 

 Dear Jeff:

 This letter is to memorialize the agreement of Somaxon Pharmaceuticals, Inc. (“Somaxon”) and The Procter & Gamble
Distributing Company LLC (“P&G”) that the Co-Promotion Agreement between Somaxon and P&G dated as of August 24, 2010, as amended (the “Agreement”), will be amended as follows (with capitalized terms used herein and
not otherwise defined having the meanings assigned to such terms in the Agreement): 
  

	1.	Notwithstanding anything to the contrary contained in the Agreement, Somaxon and P&G hereby agree that the Promotion Fees for the Quarter ended December 31,
2011 (which amount to $1,664,876 in the aggregate) shall be paid as follows: (a) $750,000 will be paid within five (5) business days after the first date set forth above, and (b) Somaxon shall pay to P&G, (i) during the
period beginning as of April 1, 2012 and running through December 31, 2012, three percent (3%) of Net Sales, and (ii) from and after January 1, 2013, six percent (6%) of Net Sales, with such payments under subclauses
(i) and (ii) continuing only until the remaining $914,876 of Promotion Fees for the Quarter ended December 31, 2011 have been paid to P&G. In the event that Somaxon (or its affiliates or sublicensees) ceases selling the Product,
for whatever reason, Somaxon shall notify P&G within seven (7) days, and within thirty (30) days of such notification, shall pay in full the remainder of any amounts owed for the Promotion Fees for the Quarter ended December 31,
2011. In the event that Somaxon realizes through current, or consummates one or more new, strategic transactions (which shall specifically exclude any transaction primarily intended as a financing transaction) involving the Product which results in
today-forward cumulative cash payments received in an amount of $10,000,000 or more, Somaxon shall pay P&G the balance owed for the Promotion Fees within 30 days of the receipt of the cash payment that causes the cumulative amount of cash
payments received to exceed $10,000,000. Strategic transactions shall include litigation settlements, licenses, development collaborations, joint ventures, or similar events. 

	2.	Notwithstanding anything to the contrary contained in the Agreement and notwithstanding paragraph 1 above, the payments due to P&G from Somaxon under
Section 8.5(d) of the Agreement during the 2012 calendar year shall continue (i.e., the payments to be made under subsection (b) of paragraph 1 above shall be in addition to, and not in lieu of, the payments to be made under
Section 8.5(d) of the Agreement), with such payment to P&G relating to the Quarter ended March 31, 2012 (which payment amounts to $82,237) to be made within five (5) business days after the first date set forth above.

  

	3.	Notwithstanding anything to the contrary contained in the Agreement, from and after April 1, 2012, the payments to be made under subsection (b) of paragraph 1
above and the payments to be made under Section 8.5(d) of the Agreement shall be made on a monthly basis as follows: (a) Somaxon will make payment to P&G with respect to each of the first two months in any calendar quarter based on
Somaxon’s good faith estimate, made in accordance with U.S. generally accepted accounting principles, consistently applied (“GAAP”), of Net Sales for such month, with such payment to be made within thirty (30) days after the end
of such month and accompanied by a statement showing Somaxon’s calculation of such Net Sales for such month, and (b) Somaxon will make payment to P&G with respect to the third month in any calendar quarter based on Somaxon’s
publicly reported financial statements, prepared in accordance GAAP, showing Net Sales for such calendar quarter, with the amount of such payment relating to such third month to be adjusted for any underpayment of overpayment relating to the
previous two months based on the estimates described above, with such payment to be made within five (5) days after the public announcement of such financial statements and accompanied by a statement showing Somaxon’s calculation of such
Net Sales for such quarter. Except as otherwise amended, all other terms of the Agreement that survived the termination of the Agreement from and after December 31, 2011 shall remain in full force and effect. 

Please evidence the agreement of P&G to the foregoing by signing below in the space provided. 

Sincerely, 
 /s/ Richard W. Pascoe 
 Richard W. Pascoe 

President and Chief Executive Officer 
 ACCEPTED AND AGREED: 
 THE PROCTER & GAMBLE DISTRIBUTING COMPANY LLC 

 

			
	Signed:	  	/s/ J.D. Weedman
		
	Name:	  	J.D. Weedman
	Title:	  	Vice President, Global Business Development

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