Document:

Amendment to Equity Line of Credit Agreement

 Exhibit 10.83 
 FIRST AMENDMENT TO 
 EQUITY LINE OF CREDIT AGREEMENT 
 This FIRST AMENDMENT TO EQUITY LINE OF CREDIT AGREEMENT (this “Amendment”) is made and entered into as of the 30th of March 2006
by and between Hopkins Capital Group II, LLC (the “Investor”) and BioDelivery Sciences International, Inc. (the “Company”). 
 WHEREAS, the Investor and the Company are parties to that certain Equity Line of Credit Agreement (the “Agreement”), dated as of September 3, 2004 and effective for all purposes as of
August 23, 2004; and 
 WHEREAS, in accordance with Section 8.1 of the Agreement, the Investor and the Company desire to
amend the Agreement as provided for herein. 
 NOW, THEREFORE, in accordance with the terms and provisions of the Agreement, and
intending legally to be bound, the Members hereby amend the Agreement as follows: 
 1. Defined Terms. All capitalized terms used but
not defined herein shall have the meanings ascribed to such terms in the Agreement. 
 2. Extension of Commitment Period. The Investor
and the Company hereby amend the Agreement to extend the Commitment Period by deleting the defined term “Commitment Period” appearing in the Agreement in its entirety and replacing it with the following: 
 “Commitment Period” shall mean the period commencing on the Effective Date and expiring on the earliest to occur of: (i) the date on
which the Investor shall have made payment of Advances pursuant to this Agreement in the aggregate amount of Four Million Dollars ($4,000,000) and (ii) December 31, 2006. 
 3. No Other Change. The Investor and the Company agree that except as modified by this Amendment, the Agreement remains unchanged and unmodified
in all respects and in full force and effect. 
 [Signature Page Follows] 
  

 1 

 IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be duly executed and
delivered on their behalf as of the date first above written. 
  

			
	INVESTOR:
	
	HOPKINS CAPITAL GROUP II, LLC
		
	By:	 	 /s/ Francis E. O’Donnell, Jr.

	Name:	 	Francis E. O’Donnell, Jr.
	Title:	 	Manager
	
	COMPANY:
	
	BIODELIVERY SCIENCES INTERNATIONAL, INC.
		
	By:	 	 /s/ Mark A. Sirgo

	Name:	 	Mark A. Sirgo
	Title:	 	President and Chief Executive Officer

  

 2Form of Mercury Executive Annual Incentive Bonus Plan

 Exhibit 10.55 
 MERCURY 
 Mercury Executive Annual Incentive Bonus Plan 
 Overview and Purpose 
 Mercury’s annual
incentive Plan was created as a means to recognize and reward the link between the achievement of Mercury’s corporate objectives and the executive’s contribution to this success. The Plan is designed to actively engage executives in
achieving performance goals by placing compensation “at risk” based on performance. The specific purpose of the Plan is to: 
  

	 	•	 	Align the risks/rewards for the senior management team to achieve Mercury’s top business priorities; 

  

	 	•	 	Motivate and retain executives by providing above market compensation opportunities linked to performance; 

  

	 	•	 	Establish a direct link between operational performance that creates shareholder value and individual performance and rewards; and 

  

	 	•	 	Align interests and objectives of shareholders and executives to drive Company growth that creates shareholder value. 

 Performance Period 
 Each year the Company
established a new performance period tied to the fiscal year. This Plan is effective for the Plan year January 1 to December 31, 20    . 
 Eligibility and Participation 
 Each year the CEO recommends to the Compensation Committee of
the Board, executive positions that are eligible to participate in the Annual Executive Incentive Plan for that fiscal year. An executive must be rated “Solid” or better through the regular performance review process for the fiscal year to
be eligible for consideration for an award under the Plan. 
 Performance Measures 
 Each year, the CEO presents to the Board, the overall operating Plan for the fiscal year that is the basis for establishing the Company’s performance
objectives under the Plan. The Plan rewards performance as measured against Mercury’s pre-defined financial objectives and individual performance (key performance indicators or KPIs). The actual measures in the Plan may change from year to year
based on the business priorities and strategies of the Company. The metrics may include, although are not limited to, the following: 
  

	 	•	 	Bookings/revenue growth 

 MERCURY 
 Mercury Executive Annual Incentive Bonus Plan 
  

	 	•	 	Earnings per share 

  

	 	•	 	Cash Flow 

  

	 	•	 	Market cap growth 

  

	 	•	 	Strategic imperatives 

 Award Pool Funding 
 The first step in the process for determining any awards is for the Company to build a funding pool following the measurement of the Company’s
performance. This pool is the amount of total dollars available for incentive awards for the executive team. The pool is based on Mercury’s financial performance for the year against the pre-established goals approved by the Board. 

Each executive position has a defined target incentive opportunity, expressed as a percent of salary, based on the competitive assessment performed by
the Company, on behalf of the Compensation Committee, annually. This target is used to determine the amount of funding contributed to the overall award pool. The sum of all executive target award opportunities as a percent of earned salary is then
adjusted by the Company’s overall performance in determining the funding of the pool. 
 For purposes of illustration, assume that there
are 10 executives with identical earned salaries of $200,000 for the fiscal year. Also assume that the target award opportunity is 50% of base salary for each position, or $100,000. Therefore, the executive bonus pool would be $1,000,000 at target
Company performance. 
 The Company must meet a minimum level of performance, referred to as the threshold, to initiate funding in the pool.
Threshold performance typically will fund the Plan at 75% of target incentive opportunities with the maximum funding under the Plan being 150% of target unless adjusted by the Compensation Committee of the Board in their sole discretion. 

Determining Individual Awards 
 Once the
award pool is funded, the CEO or other senior management complete the annual executive performance review process to determine the executive’s individual performance versus their pre-established objectives. Individual award payouts may range
from 0% to 150% of target opportunity based on the 
  

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 MERCURY 
 Mercury Executive Annual Incentive Bonus Plan 
 executive’s performance as assessed in the review
process. This approach is consistent with Mercury’s commitment to a pay-for-performance philosophy and culture. 
 Mercury’s Board
of Directors maintains the discretion to determine any funding of the Plan if the Company’s performance does not meet threshold levels or if the Company significantly exceeds plan. 
 Administration 
 Incentive awards will be prorated for executives who join Mercury during the
year and are based on earned salary during the fiscal year. 
 Awards will typically be paid within the quarter following the close of the
fiscal year, once final financial results are known and approved by the Board. Incentive awards are subject to all applicable payroll taxes consistent with Mercury’s standard operating procedures. 
 Mercury reserves the right to modify the Plan, and individual awards, at any time. Plan participants will be notified of any Plan changes. 
 Acknowledgement 
 My signature below indicates
that I have received a copy of the Plan and that my target incentive opportunity has been communicated to me. 
  
  

							
		 	  
	 		 	  

		 	Signature	 		 	Date

  

 3 

 MERCURY 
 Participation Notice 
 Mercury Interactive Corporation 
 Annual Executive Incentive Plan 
 Name: Employee Name 
 Title: Employee Title 
 Performance Period:                                  
      January 1 through December 31, 20     
 Capitalized terms used in this
Participation Notice (“Notice”) but not otherwise defined shall have the respective meanings ascribed to them in the Annual Incentive Plan (the “Plan”) attached hereto as Exhibit A and incorporated herein by this reference.

 Performance Goals and Program Funding: 
  

	•	 	The amount of funding in the plan is based on the Company’s achievement (as determined by the Committee in its sole discretion) of the Performance Goals as set forth in
attached matrix as Exhibit B and incorporated herein by this reference. 

  

	•	 	Individual performance goals will be set and determined as part of the annual goal setting process and are attached as Exhibit C and incorporated herein by this reference.
These goals will be used in determining the executive’s actual performance against goals in determining any award under the Plan. 

 Performance measurement exceptions: 
  

	•	 	Non-GAAP Earnings per share (“EPS”) and Revenue Growth of the Company (together, the “Criteria”), with the targets set based on the Company’s Business Plan
for the Performance Period approved by the Company’s Board of Directors. 

  

	•	 	Plan adjustments may be made each year as part of the goal setting process, and as deemed to be reasonable and fair as assessed by the Compensation Committee of the Board, in their
sole discretion. Planned adjustments are reflected in Exhibit B. 

 Payment of Cash Awards: 
  

	•	 	Payment of cash awards will typically be made in the first quarter following the close of the fiscal year, once performance is known and approved by the Board of Directors.

 Examples: 
  

	•	 	If the Company achieves the minimum Performance Goal for each of the Criteria, then the Participant is eligible for a cash award equal to 75% of the total incentive opportunity,
which will then be adjusted based on their actual contribution based on the pre-established goals. 

  

	•	 	If the Company does not achieve the minimum Performance Goal for each of the Criteria, then the plan will go un-funded and no individual awards will be made, unless if the
Compensation Committee, in their sole discretion, provided funding to the program. 

  

	•	 	I hereby acknowledge and agree that my Mercury Interactive Corporation Annual Incentive Plan is comprised of this Participation Notice listing my Performance Goals and the Criteria
on which they are based together with the Plan attached hereto as Exhibit A and incorporated herein by this reference (collectively, this “Notice/Plan”). I further acknowledge and agree that this Notice/Plan is effective during the
Performance Period, unless modified in writing. Each new/modified Notice/Plan supersedes and cancels all previous Notice/Plans and any other oral or written commitment with respect to the subject matter of this Notice/Plan. 

 

									
	“Participant”	 		 	Mercury Interactive Corporation
					
	Signature:	 	  
	 		 	By:	 	  

	Date:	 	  
	 		 	Name:	 	  

		 		 		 	Its:

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