Document:

EX-10.2

 Exhibit 10.2 

AGREEMENT OF SUBLEASE 
 IMCLONE
SYSTEMS, LLC, 
 as Sublandlord 

and 
 MEIRAGTX, LLC, 

as Subtenant 
 PREMISES AT 

450 East 29th Street 
 NEW YORK,
NEW YORK 
 Entire 14th Floor 

May 31, 2019 

 TABLE OF CONTENTS 

 

							
	 Paragraph
	  	 	  	Page	 
	 1.
	  	Term	  	 	1	 
	 2.
	  	Fixed Rent	  	 	2	 
	 3.
	  	Use of the Sublease Premises	  	 	3	 
	 4.
	  	Incorporation of Overlease Terms, No Violoation of Overlease	  	 	3	 
	 5.
	  	Sublease Subject to Overlease	  	 	4	 
	 6.
	  	Inapplicability of Certain Overlease Provisions	  	 	5	 
	 7.
	  	Additional Rent	  	 	6	 
	 8.
	  	Subleases, Assignments, etc	  	 	7	 
	 9.
	  	Performance of Overlease	  	 	7	 
	 10.
	  	Electrical System Maintenance	  	 	8	 
	 11.
	  	Brokerage	  	 	8	 
	 12.
	  	Assignment of Overlease	  	 	8	 
	 13.
	  	Damage, Destruction and Other Casualty	  	 	9	 
	 14.
	  	Payments	  	 	9	 
	 15.
	  	Notices	  	 	9	 
	 16.
	  	Consent by Overlandlord	  	 	10	 
	 17.
	  	Binding Effect	  	 	10	 
	 18.
	  	Modification, Waiver, etc	  	 	10	 
	 19.
	  	Right of Sublandlord to Perform Subtenant’s Covenants, etc	  	 	11	 
	 20.
	  	Acceptance of Rent; Surrender	  	 	11	 
	 21.
	  	Waiver of Jury Trial; Counterclaims	  	 	11	 
	 22.
	  	Insurance	  	 	11	 
	 23.
	  	“As Is” Condition	  	 	12	 
	 24.
	  	End of Term	  	 	13	 
	 25.
	  	Alterations	  	 	13	 
	 26.
	  	Security Deposit	  	 	14	 
	 27.
	  	Indemnification	  	 	14	 
	 28.
	  	Sublandlord’s Liability; Limitations Thereon	  	 	15	 
	 29.
	  	Anti-Terrorism Representations	  	 	16	 
	 30.
	  	Miscellaneous	  	 	17	 

							
			
	 EXHIBIT A
	  	Overlease	  			
			
	 EXHIBIT B
	  	Floor Plan of Subleased Premises	  			
			
	 SCHEDULE 1
	  	Personal Property	  			

 AGREEMENT OF SUBLEASE 

THIS AGREEMENT OF SUBLEASE (this “Sublease”) dated as of the 31st day of May, 2019,
between IMCLONE SYSTEMS, LLC, a Delaware limited liability company (“Sublandlord”), and MEIRAGTX, LLC, a Delaware limited liability company
(“Subtenant”). 
 R E C I T A L
S: 
 (a)    By Lease Agreement dated July 20, 2009 (the “Original
Overlease”), between ARE-East River Science Park, LLC (“Overlandlord”), as landlord, and Sublandlord, as successor-in-interest to Imclone Systems Corporation, as tenant, Sublandlord leased from Overlandlord approximately 90,884 rentable square feet on floors 10 through 14 (the
“Overlease Premises”) in the building located at 450 East 29th Street, New York, New York (the “Building”) (and more fully described in the Original
Overlease). 
 (b)    The Original Overlease was modified by that certain First Amendment to Lease dated as of
December 31, 2010 (the “First Amendment”) and that certain Second Amendment to Lease dated November 11, 2015 (the “Second Amendment,” and together with the
Original Overlease and the First Amendment, the “Overlease”), a copy of the Overlease (with certain confidential terms omitted) is attached hereto as Exhibit A and made part hereof. 

(c)    Subtenant desires to sublet from Sublandlord a portion of the Overlease Premises (the “Sublease
Premises”) consisting of the entire 14th floor (22,721 rentable square feet) as designated on Exhibit B attached hereto and made a part hereof. 

NOW, THEREFORE, the parties hereto, in consideration of the mutual covenants, conditions and agreements hereinafter contained, do hereby agree
as follows: 
 W I T N E S S E T H: 

1.    Term and Delivery of Sublease Premises. (a) Sublandlord hereby sublets the Sublease Premises to
Subtenant and Subtenant hereby hires the Sublease Premises from Sublandlord, for a term to commence on the first day of the next calendar month following the later to occur of (a) delivery of possession of the Sublease Premises to Subtenant
with the interconnecting stair connecting the 12th floor with the 14th floor enclosed, and (b) the date on which Overlandlord’s consent to this Sublease is received pursuant to and subject to Section 16 of this Sublease and the
Demising Work (as hereinafter defined) is substantially completed (such date, the “Commencement Date”), which date is anticipated to be [August 1], 2019, and to end on October 31, 2026, or such
earlier date on which this Sublease is terminated in accordance with the provisions hereof (such earlier date, the “Expiration Date”). 

(b)    Provided no Default exists at the time of the giving of notice by Subtenant (a “Termination
Notice”) and on the proposed accelerated Expiration Date set forth in the Termination Notice, Subtenant shall have the right to accelerate the Expiration Date of this Sublease to a date which is the last day of any
calendar month occurring after the fifth (5th) anniversary of the Commencement Date by providing to Sublandlord such Termination Notice at least [six (6) months] in advance of such accelerated Expiration Date. If Subtenant provides Sublandlord
with a Termination Notice and provided no Default exists as of the proposed accelerated Expiration Date, then the proposed accelerated Expiration Date shall be the Expiration Date for all purposes under this Sublease. 

 (c)    Sublandlord shall deliver the Sublease Premises to Subtenant on
the Commencement Date in the condition required under Section 23 of this Sublease. If Subtenant occupies or otherwise has possession of the Sublease Premises prior to the Commencement Date for the conduct of Subtenant’s business, Subtenant
covenants and agrees that such occupancy shall be deemed to be under all the terms, covenants, and provisions of this Sublease, including the covenant to pay Fixed Rent and Additional Rent as such terms are hereinafter defined). On the Commencement
Date, Sublandlord shall also deliver to Subtenant the furniture and other property of Sublandlord set forth on Schedule 1 attached hereto (the “Personal Property”) for no
additional consideration, which Subtenant shall have the right to use during the term of this Sublease, but which shall remain the property of Sublandlord and shall be returned to Sublandlord in “as is” condition upon the expiration or
earlier termination of this Sublease. Subtenant shall reasonably cooperate with Sublandlord in connection with the removal of the Personal Property from the Sublease Premises at the end of the Sublease term. 

(d)    Transferable Lab Permits. Promptly following the Commencement Date, Sublandlord shall assign and transfer to
Subtenant all transferable laboratory permits applicable to the Sublease Premises. 
 2.    Fixed Rent. 

(a)    Subtenant covenants and agrees to pay to Sublandlord (or as Sublandlord may otherwise designate by written notice to
Subtenant), in lawful money of the United States without any prior notice or demand therefor, a fixed annual rental (the “Fixed Rent”) in the following amounts during the following periods: 

(i)    From the Commencement Date through March 31, 2020, $1,931,285.00 per annum in monthly installments of
$160,940.42; 
 (ii)    From April 1, 2020 through March 31, 2021, $1,989,223.55 per annum in monthly
installments of $165,768.63; 
 (iii)    From April 1, 2021 through March 31, 2022, $2,048,900.26 per annum in
monthly installments of $170,741.69; 
 (iv)    From April 1, 2022 through March 31, 2023, $2,110,367.27 per
annum in monthly installments of $175,863.94; 
 (v)    From April 1, 2023 through March 31, 2024,
$2,173,678.28 per annum in monthly installments of $181,139.86; 
 (vi)    From April 1, 2024 through March 31,
2025, $2,238,888.63 per annum in monthly installments of $186,574.05; 
 (vii)    From April 1, 2025 through
March 31, 2026, $2,306,055.29 per annum in monthly installments of $192,171.27; and 

  
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 (viii)    From April 1, 2026 through the Expiration Date,
$2,375,236.95 per annum in monthly installments of $197,936.41. 
 Fixed Rent shall be payable in advance on the first day of each calendar
month during the term from the Commencement Date through and including the Expiration Date, together with Additional Rent (hereinafter defined), without any deduction, offset or abatement whatsoever. The first such payment of Fixed Rent shall be
deposited with Sublandlord upon execution of this Sublease, to be applied by Sublandlord to the first Fixed Rent payment due hereunder. 

(b)    All amounts due from Subtenant to Sublandlord under this Sublease shall be paid by wire transfer of immediately
available funds to an account designated in writing by Sublandlord. The monthly Fixed Rent payable on account of any partial calendar month during the term, if any, shall be prorated on a per diem basis. 

(c)    As used in this Sublease, the term “Business Day” shall mean any day other than Saturdays, Sundays
and public United States holidays. 
 3.    Use of the Sublease Premises; No Violation of Overlease. Subtenant
shall use and occupy the Sublease Premises solely for the permitted purpose use set forth in the Base Lease Provisions and Section 7 of the Overlease. Subtenant shall not use the Sublease Premises for any other purpose, and Subtenant covenants
not to do any act which will result in a violation of the Overlease or Overlandlord’s consent to this Sublease. 

4.    Incorporation of Overlease Terms. (a) Words or terms that are capitalized but not defined herein shall
have the respective meanings ascribed thereto in the Overlease unless the context clearly requires otherwise. Except as herein otherwise expressly provided, all of the terms, provisions, covenants and conditions contained in the Overlease are hereby
made a part hereof. Subtenant acknowledges that it has read and examined the Overlease and is fully familiar with the terms, provisions, covenants and conditions contained therein. 

(b)    The rights and obligations contained in the Overlease are, during the term of this Sublease, hereby imposed upon
the respective parties hereto, Sublandlord being substituted for the landlord under the Overlease and Subtenant being substituted for the tenant under the Overlease; provided, however, that Sublandlord shall not be liable to Subtenant
for any failure in performance resulting from the failure in performance by Overlandlord under the Overlease and Sublandlord’s obligations hereunder are accordingly conditional where such obligations require such parallel performance by
Overlandlord. Subtenant recognizes that notwithstanding the incorporation of the provisions of the Overlease (other than the Excluded Provisions (as hereinafter defined)) by reference, Sublandlord is not in a position to render any of the services
or to perform any of the obligations of Overlandlord as set forth in the Overlease and incorporated by reference herein by the terms of this Sublease; Sublandlord agrees, however, to use reasonable efforts (which reasonable efforts shall not
include participation in any legal or administrative proceedings) to enforce its rights pursuant to the Overlease for the benefit of Subtenant upon Subtenant’s written request, and Subtenant agrees to immediately reimburse Sublandlord for any
and all reasonable costs incurred with respect to third parties in expending such efforts. In amplification and not in limitation of the foregoing and without any allowance to 

  
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Subtenant or other reduction, abatement or adjustment of Fixed Rent or Additional Rent, Sublandlord shall not be responsible for furnishing elevator, electric, HVAC, cleaning, painting, window
washing or other services, nor for any maintenance or repairs in or to the Building or the Sublease Premises, but shall use its reasonable efforts in accordance with the terms and conditions of the immediately preceding sentence to enforce its
rights pursuant to the Overlease for the benefit of Subtenant upon Subtenant’s written request. In addition to the foregoing, no such failure or default on the part of Overlandlord shall constitute an actual or constructive total or partial
eviction of Subtenant or entitle Subtenant to a reduction or abatement of Fixed Rent or Additional Rent hereunder. 

(c)    Notwithstanding the generality of clause (a) above, for the purposes of incorporation of the terms,
provisions, covenants and conditions contained in the Overlease herein, the term “Tenant” in the Overlease shall mean and refer to Subtenant hereunder; the term “Landlord” in the Overlease shall mean and refer to Sublandlord
hereunder; the term “the Premises” in the Overlease shall mean and refer to the Sublease Premises hereunder; the terms “Base Rent” and “Additional Rent” in the Overlease shall mean and refer to the Fixed Rent and
Additional Rent respectively, hereunder; the term “this Lease” in the Overlease shall mean and refer to this Sublease; the term “Commencement Date” in the Overlease shall mean and refer to the Commencement Date hereunder. 

5.    Sublease Subject to Overlease. (a) This Sublease is expressly made subject to all the terms and
conditions of the Overlease, except as specifically provided to the contrary in this Sublease, to the extent applicable to the Sublease Premises. Subtenant hereby assumes, and covenants that it will, throughout the term hereof, observe all of the
provisions of the Overlease, on the part of Sublandlord to be performed as the tenant thereunder (except for the Excluded Provisions), and that Subtenant will not do any act, matter or thing which will be, result in, or constitute a violation or
breach of or a default under the Overlease; any such violation, breach or default shall constitute the breach by Subtenant of a substantial obligation under this Sublease. Subtenant shall indemnify and hold Sublandlord harmless from and against all
claims, penalties and actual out-of-pocket expenses, including reasonable attorneys’ fees and disbursements, based upon any default by Subtenant, during the term
hereof, in Subtenant’s performance of those terms, covenants and conditions of the Overlease which are or shall be applicable to Subtenant, as above provided, except to the extent such default results from Sublandlord’s gross negligence or
willful misconduct, and Subtenant shall pay to Sublandlord as Additional Rent hereunder any and all sums which Sublandlord is required to pay to Overlandlord, which requirement is caused in whole or in part by Subtenant’s failure to perform or
observe any of the terms or conditions of the Overlease pertaining to the Sublease Premises that Subtenant is required to perform or observe or by any act or omission described in the preceding sentence. Sublandlord represents and warrants that as
of the date hereof, it is in compliance in all material respects with the terms, covenants and conditions of the Overlease pertaining to the Sublease Premises, specifically including but not limited to Sections 43 and 44 of the Overlease.
Sublandlord represents and warrants that as of the date hereof, Sublandlord’s occupancy of the Overlease Premises is in compliance in all material respects with all applicable laws. Notwithstanding (x) anything to the contrary in this
Sublease and (y) the incorporation of any terms of the Overlease, in any case where the consent or approval of Overlandlord shall be required pursuant to the Overlease, Overlandlord’s and Sublandlord’s respective consent shall be
required hereunder. Any conflicts between the terms, covenants and conditions of this Sublease and the Overlease shall be resolved in favor of this Sublease, provided such terms, covenants or conditions are not prohibited by the terms of the
Overlease. 

  
 4 

 (b)    This Sublease is subject and subordinate to the Overlease and to
all matters to which the Overlease is or shall be subordinate, and in the event of termination, re-entry or dispossess by Overlandlord under the Overlease, Subtenant shall, at Overlandlord’s option, attorn to Overlandlord pursuant to the then
executory provisions of this Sublease, and so long as Subtenant is not in Default under this Sublease, Overlandlord hereby agrees not to disturb Subtenant’s subtenancy of the Sublease Premises. Notwithstanding the foregoing, Overlandlord shall
not (i) be liable for any previous act or omission of Sublandlord under this Sublease, (ii) be subject to any offset not expressly provided in this Sublease which shall have theretofore accrued to Subtenant against Sublandlord, or
(iii) be bound by any previous modification of this Sublease or by any previous prepayment of more than one (1) month’s Fixed Rent or Additional Rent. Subtenant covenants and agrees to execute and deliver, at any time and from time to
time, upon the request of Sublandlord or Overlandlord, any instrument which may be necessary or appropriate to evidence such attornment. 

6.    Inapplicability of Certain Overlease Provisions. The following Articles, Sections, and Exhibits of the
Overlease shall not be applicable to this Sublease and shall be excluded from the incorporation by reference into this Sublease (all of such inapplicable provisions, collectively, the “Excluded
Provisions’’): 
 (a)    The Basic Lease Provisions regarding Base Rent, Tenant’s
Share of Operating Expenses, Target Commencement Date, Rent Commencement Date, Base Term, and Sections 1(b) [Storage Space], 1(c) [License for Certain Building Amenities], 2, 3(a), 4, 5 [Operating Expense Payments], 6 [Guaranty], 10(a) [Parking],
10(b) [Shuttle], 11(b)(iv) [generator], 12(a) [alterations], 17(f) [financial covenant], 35 [brokers], 38 [signage], 46, 47, 48, 49, 50, and 51, and Exhibits C, E, F, G, I, K, and L; and 

(b)    In addition, the following further modifications to certain Overlease provisions shall apply: 

(i)    In lieu of the payment Subtenant’s share of Operating Expenses as provided in Section 5 of the Overlease,
Sublandlord and Subtenant have agreed that, pursuant to Section 7 of this Sublease, Subtenant shall pay a fixed charge (the “Operating Expense Charge”) initially equal to $34.35 per square foot of
the Sublease Premises, or One Hundred Eighty Thousand Four Hundred Sixty-Six and 35/100 Dollars ($180,466.35) per annum ($15,037.20 per month), which fixed charge shall be increased annually from and after
each April 1st by three percent (3%) on a cumulative basis (i.e. from and after April 1, 2020 the Operating Expense Charge payable by Subtenant shall be increased to $185,859.74 per annum ($15,488.31 per month) and from and after April 1
2021 the Operating Expense Charge payable by Subtenant shall be increased to $191,435.53 per annum ($15,952.96 per month), etc.). 

  
 5 

 (ii)    The words “date hereof” in the Overlease shall be
deemed to read “date of this Sublease.” 
 (iii)    Any and all references to the Designated Use Area are
deleted. 
 (iv)    Supplementing Section 11 of the Overlease as incorporated into this Sublease, pursuant to
Section 7 of this Sublease, Subtenant shall pay to Sublandlord Subtenant’s pro rata share based on the relative square footage of the Sublease Premises and the Overlease Premises (the “Utility Cost
Share”) of the cost to Sublandlord of all Utilities other than electricity provided to the Overlease Premises (including the Sublease Premises) pursuant to Section 11 of the Overlease. Regarding electricity, Subtenant
shall pay all charges for electric service to the Sublease Premises as measured by the separate electric meter serving the Sublease Premises (“Electricity Charges”). 

If an Excluded Provision contains the definition of a defined term used in an incorporated provision or is specifically referenced in this Sublease, such
Excluded Provision shall be deemed incorporated solely for such purpose. 
 7.    Additional Rent. (a) In
addition to the Fixed Rent hereunder, Subtenant covenants to pay as Additional Rent all monetary obligations of any kind Subtenant incurs directly with the Overlandlord under the Overlease, including, but not limited to, overtime charges for heating
and air conditioning, window cleaning or other services, any similar or other obligations incurred from time to time by Subtenant, and any charges in connection with the installation and operation of Subtenant’s supplemental HVAC, if any.
Subtenant acknowledges and agrees that the Fixed Rent set forth herein does not include Additional Rent, including the Operating Expense Charge, Subtenant’s Utility Cost Share of the cost of Utilities provided to the Sublease Premises,
Electricity Charges, overtime charges for heating and air conditioning or for cleaning, janitorial, rubbish removal and other such services. With respect to such overtime or extra services, Sublandlord is not responsible for providing such services,
and Subtenant shall be solely responsible for requesting such services directly from Overlandlord and for paying Overlandlord for the same, or for having Overlandlord approve independent contractors for same to be paid directly by Subtenant. 

(b)    Additional Rent payable by Subtenant hereunder shall include monthly payments of the Operating Expense Charge and
Subtenant’s Utility Cost Share of all Utilities (other than electricity) and Electricity Charges provided to the Overlease Premises by Overlandlord. Each year during the term of this Sublease, Sublandlord shall provide Subtenant with an annual
budget setting for the estimated monthly payment for Subtenant’s Utility Cost Share and Subtenant shall make such payment together with the monthly payment of Fixed Rent. If actual Utility costs payable by Sublandlord under the Overlease for
any period differ from the amounts set forth in the applicable annual budget and upon which Subtenant’s Utility Cost Share payments have been based, then Sublandlord shall deliver to Subtenant and itemized reconciliation statement of the actual
costs and either (i) Sublandlord shall promptly refund to Subtenant any excess amount paid by Subtenant or (ii) Subtenant shall pay to Sublandlord any shortfall as set forth in the reconciliation statement provided by Sublandlord. 

  
 6 

 (c)    In addition to the Fixed Rent hereunder, Subtenant covenants to
pay all charges under the Overlease attributable to the Sublease Premises or Subtenant’s acts. 
 (d)    For
purposes of this Sublease, the term “Additional Rent” shall mean all sums payable by Subtenant under this Sublease other than Fixed Rent. All Additional Rent shall be paid without any abatement, deduction or
setoff whatsoever. Subtenant’s obligation to pay all Fixed Rent and Additional Rent set forth herein shall survive the expiration of the term of this Sublease. 

8.    Subleases. Assignments, etc. (a) Subtenant shall not, by operation of law or otherwise, assign this
Sublease or any interest therein or sublet any portion or all of the Sublease Premises or request any consent from Overlandlord with respect to the same, except in accordance with the provisions of Section 22 of the Overlease, as incorporated
herein by reference. Subtenant acknowledges and agrees that any sublease or assignment by Subtenant shall require the consent of Overlandlord. 

(b)    Any attempted assignment or subletting made contrary to the provisions of this Section 8 or Article 22 of the
Overlease (as incorporated herein) or to Overlandlord’s consent to this Sublease shall be null and void. No consent by Sublandlord or Overlandlord to any assignment or subletting shall in any manner be considered to relieve Subtenant from
obtaining Sublandlord’s or Overlandlord’s express written consent to further assignment or subletting. 

(c)    If this Sublease is assigned in contravention of this Sublease or the Overlease, or if the Sublease Premises or any
part thereof is sublet or occupied by anyone other than Subtenant, Sublandlord may, after default by Subtenant, collect Fixed Rent and Additional Rent from the assignee, subtenant or occupant, and apply the net amount collected to the Fixed Rent and
Additional Rent herein reserved, but no such assignment, subletting, occupancy or collection of Fixed Rent and Additional Rent shall be deemed a waiver of the covenants in this Section 8, nor shall it be deemed acceptance of the assignee,
subtenant or occupant as a tenant, or a release of Subtenant from the full performance of all the terms, conditions and covenants of this Sublease. 

9.    Performance of Overlease. (a) The respective terms, covenants, provisions and conditions of the
Overlease on the part of Overlandlord to be performed, which have been incorporated herein by reference or as covenants and obligations of Sublandlord hereunder, are to be performed by Overlandlord or its successors and assigns, Subtenant shall look
solely to Overlandlord for such performance. Sublandlord shall not be liable or responsible to Subtenant for any failure or default on the part of Overlandlord, its successors or assigns, with respect to any of the terms, covenants, provisions and
conditions of the Overlease. 
 (b)    If Subtenant shall default in the payment of Fixed Rent or Additional Rent
hereunder or in the performance or observance of any of the terms, covenants or conditions of this Sublease or the Overlease on the part of Subtenant to be performed or observed, either directly or as incorporated herein, Sublandlord shall have the
right (but not the obligation) to exercise all of the same rights and remedies provided to or reserved by Overlandlord in the Overlease and at law and equity; provided however, the foregoing shall in no way be deemed to

  
 7 

 
limit or impair the rights and privileges of Overlandlord under the Overlease, or to impose any obligations on the part of Sublandlord by reason of the exercise by Overlandlord of any of such
rights or privileges with respect to the Sublease Premises or to the use and occupation thereof by Subtenant. Without limiting the foregoing, Sublandlord shall have the same rights and remedies in the event of
non-payment by Subtenant of Fixed Rent or Additional Rent under this Sublease as are available to Overlandlord under the Overlease and at law and in equity for the non-payment of Fixed Rent, Additional Rent
and/or of any installment thereof. 
 (c)    Subtenant shall, within three (3) days after receipt thereof, notify
Sublandlord of any notice applicable to the Sublease Premises served by Overlandlord upon Subtenant pursuant to the terms, provisions and conditions of the Overlease. Wherever Overlandlord requires Sublandlord, as tenant under the Overlease (except
in respect of any Excluded Provision), to take any action or to cure any default applicable to the Sublease Premises within a period of time stated therein or in the Overlease, Subtenant shall complete such action or cure such default not later than
five (5) days prior to the expiration of such period and shall immediately furnish notice of such compliance to Sublandlord. Wherever in the Overlease Overlandlord is required to consent to or approve any matter within a set time period, the
Overlease as incorporated herein shall be deemed to have five (5) Business Days added to such time period. 

10.    Electrical System Maintenance. Subtenant, at its sole cost and expense, shall be responsible for any repair,
maintenance and replacement of any electric meter, panel board and all wires, wiring, feeders and risers serving the Sublease Premises, and Subtenant shall pay Sublandlord’s reasonable charges therefor on demand. Subtenant covenants that at no
time shall the use of electrical energy in the Sublease Premises exceed the capacity of the existing feeders or wiring installations then serving the Sublease Premises. Subtenant shall not make or perform, or permit the making or performance of, any
alterations to wiring installations or other electrical facilities in or serving the Sublease Premises or any additions to the business machines, office equipment or other appliances (other than customary low energy consuming office machines) in the
Sublease Premises that utilize electrical energy, without the prior consent of Sublandlord in each instance. 

11.    Brokerage. Each of Subtenant and Sublandlord covenants, warrants and represents that it has dealt with no
broker or agent and that no other broker, agent, finder or other consultant was instrumental in bringing about or consummating this Sublease, and that it has not had any conversations or negotiations with any broker, agent, finder or other
consultant concerning the leasing of the Sublease Premises. Each party agrees to indemnify, pay, defend and hold harmless the other party against any and all claims, actual
out-of-pocket costs, expenses or liabilities for any compensation, charges, brokerage commissions or finder’s fees by brokers, agents or persons claiming to have
dealt through or with such party in connection with the leasing of the Sublease Premises and all actual out-of-pocket costs, expenses and liabilities, incurred in
connection with such claims, including reasonable attorneys’ fees and disbursements. 
 12.    Assignment of
Overlease. The term “Sublandlord” as used in this Sublease means only the tenant under the Overlease at the time in question, so that in the event the Overlease is assigned by tenant thereunder, the assignor shall thereupon be released
and discharged from all covenants, conditions and agreements of Sublandlord hereunder accruing from and after the date of such assignment, but such covenants, conditions and agreements shall be binding on the assignee until thereafter assigned. 

  
 8 

 13.    Damage, Destruction and Other Casualty; Condemnation. If
the Sublease Premises or any portion thereof shall be damaged by fire or other casualty or be condemned or taken in any manner for a public or quasi-public use, Subtenant agrees that it shall be the obligation of the Overlandlord, if any, and not of
Sublandlord to repair, restore or rebuild the Sublease Premises in accordance with the terms of the Overlease. In the event of such casualty or condemnation, this Sublease shall continue in full force and effect, unless in connection therewith
Overlandlord or Sublandlord terminates the Overlease pursuant to the provisions thereof. Pending restoration of any damage caused by such casualty or taking, Fixed Rent and Additional Rent payable hereunder shall not be abated or apportioned in any
manner; provided, however, that if the rent payable by the Sublandlord under the Overlease shall be abated pursuant to the terms of the Overlease, Subtenant’s Fixed Rent or Additional Rent, as applicable, shall be abated hereunder if, and only
to the extent that, the abatement affects the Sublease Premises. In the event of a condemnation or taking, Subtenant hereby acknowledges that it shall not be entitled to any portion of any award received by Sublandlord with respect to the Overlease,
this Sublease or the Sublease Premises. The parties agree that this Section 13 constitutes an express agreement governing any case of damage or destruction of the Sublease Premises or the Building by fire or other casualty and Section 227
of the New York Real Property Law and any other law of like import now or hereafter in force shall have no application. 

14.    Payments. (a) Notwithstanding anything contained elsewhere in this Sublease to the contrary, unless
directed by Sublandlord to make payments directly to Overlandlord, Subtenant shall make all payments hereunder to Sublandlord at the address set forth on page 1 hereof, and the due date of each such payment shall be deemed to be the earlier to occur
of (i) the date provided in this Sublease, and (ii) five (5) Business Days earlier than (x) the date provided in the Overlease and (y) five (5) Business Days after Subtenant has received a statement for such amounts due from
Sublandlord; it being understood and agreed, however, that Fixed Rent shall be due and payable on the date provided in Section 2 hereof. 

(b)    If any payment hereunder is not received by Sublandlord within three (3) days after such payment is due, then
Subtenant shall pay interest on such overdue amount at the prime rate announced by Citibank, N. A., or its successor entity, plus four percent (4%) (the “Overdue Rate”) from the date such payment was due and such
interest shall be due and payable on demand. Nothing in this Section or in any other provision of this Sublease shall constitute an extension of the time for payment of any amounts due hereunder. 

15.    Notices. (a) All notices hereunder to Sublandlord or Subtenant shall be given in writing and mailed by
certified or registered mail, nationally recognized overnight delivery service, or hand delivered to the following addresses: 
 If to
the Sublandlord: 
 ImClone Systems, LLC 

c/o Eli Lilly and Company 
 Lilly
Corporate Center Drop Code 2046 
 Indianapolis, Indiana 46285 

Attn: Strategic Real Estate 

  
 9 

 If to the Subtenant: 

MEIRAGTX, LLC 
 c/o MeiraGTx - US

 430 East 29th Street, 10th Floor 

New York, NY 10016 
 Attn: Richard
Giroux 
          Chief Operating Office 

(b)    Notices shall be deemed received three (3) Business Days after mailing thereof, if mailed by certified
registered mail, and on the date delivered, if hand delivered or sent by nationally recognized overnight courier. By notice given in the aforesaid manner, either party hereto may notify the other as to any change as to where and to whom such
party’s notices are thereafter to be addressed. 
 16.    Consent by Overlandlord. 

(a)    The effectiveness of this Sublease is conditioned upon the delivery by Sublandlord to Overlandlord of certain
documentation and a copy of this Sublease and the receipt of the written consent of Overlandlord to this Sublease, in accordance with the terms of the Overlease. If such consent is not received by the date hereof, the Commencement Date shall be the
date on which possession of the Sublease Premises is delivered to Subtenant. Sublandlord shall (i) use commercially reasonable efforts to procure Overlandlord’s consent to this Sublease and (ii) promptly notify Subtenant of the
receipt of such consent and to provide Subtenant with a copy of same. 
 (b)    Subtenant shall provide to Sublandlord
such non-confidential documentation as may be requested by Overlandlord pursuant to the Overlease in connection with Overlandlord’s consideration of this Sublease. Each of Sublandlord and Subtenant agrees
to execute any customary or otherwise reasonable consent, if the same shall be required by Overlandlord. 

17.    Binding Effect. The covenants, conditions and agreements contained in this Sublease shall bind and inure to
the benefit of the parties hereto and their respective legal representatives and successors, and assigns (to the extent permitted hereunder). 

18.    Modification, Waiver, etc. No modification or waiver of any of the terms hereof shall be valid or binding on
either party, unless in writing duly executed by both of the parties hereto. No waiver by either party hereto of any breach or default or delinquency hereunder by the other and no failure by either party hereto to require performance or satisfaction
of any provision of this Sublease, shall be deemed a waiver of any subsequent breach, default or delinquency of the same or similar nature by the other, or as a waiver of the provision itself or of the full right of the claiming party to require
such performance or satisfaction at any time thereafter. No failure of either party hereto to exercise any right, privilege, discretion or power given it under the Sublease, or to insist upon strict compliance by the other party with any

  
 10 

 
obligation in this Sublease, and no custom or practice of either party hereto (or otherwise) at variance with the terms hereof shall constitute a waiver or modification of its right to demand
exact compliance with the terms of this Sublease. 
 19.    Right of Sublandlord to Perform Subtenant’s
Covenants, etc. If Subtenant shall have defaulted in the observance or performance of any term or covenant on Subtenant’s part to be observed or performed under or by virtue of any of the terms or provisions of this Sublease, then, unless
otherwise provided elsewhere in this Sublease, Sublandlord may immediately or at any time thereafter and without further notice perform the same for the account of Subtenant, and if Sublandlord makes any expenditures or incurs any obligations for
the payment of money in connection therewith, including, but not limited to, attorneys’ fees and disbursements in instituting, prosecuting or defending any action or proceeding, such sums paid or obligations incurred with interest at the
Overdue Rate and costs shall be deemed to be Additional Rent hereunder and shall be paid by Subtenant to Sublandlord within five (5) days after rendition of any bill or statement to Subtenant therefor. 

20.    Acceptance of Rent; Surrender. The receipt by Sublandlord of Fixed Rent and/or Additional Rent with
knowledge of the breach of any covenant of this Sublease shall not be deemed a waiver of such breach and no provision of this Sublease shall be deemed to have been waived by Sublandlord unless such waiver is in writing signed by Sublandlord. No
payment by Subtenant or receipt by Sublandlord of a lesser amount than the Fixed Rent and/or Additional Rent herein stipulated shall be deemed to be other than on account of the earliest stipulated Fixed Rent and/or Additional Rent, as the case may
be, nor shall any endorsement or statement of any check or any letter accompanying any check or payment as Fixed Rent and/or Additional Rent be deemed an accord and satisfaction, and Sublandlord may accept such check or payment without prejudice to
Sublandlord’s right to recover the balance of such rent or pursue any other remedy provided in this Sublease. No act or thing done by Sublandlord or Sublandlord’s agents during the term hereof shall be deemed an acceptance of a surrender
of the Sublease Premises and no agreement to accept such surrender shall be valid unless in writing signed by Sublandlord. No employee of Sublandlord or Sublandlord’s agent shall have any power to accept the keys to the Sublease Premises prior
to the termination of this Sublease, and the delivery of keys to any such agent or employee shall not operate as a termination of this Sublease or a surrender of the Sublease Premises. 

21.    Waiver of Jury Trial; Counterclaims. Sublandlord and Subtenant hereby waive trial by jury in any action,
proceeding or counterclaim brought by either of them against the other on any matter whatsoever arising out of or in any way connected with this Sublease, the relationship of Sublandlord and Subtenant, Subtenant’s use or occupancy of the
Sublease Premises, and any emergency statutory or any other statutory remedy. It is further mutually agreed that in the event Sublandlord commences any summary proceeding, Subtenant will not interpose any counterclaim of whatever nature or
description in any such proceeding. 
 22.    Insurance. 

(a)    Subtenant’s Insurance. Subtenant shall maintain and keep in full force and effect during the term of
this Sublease, at its own cost and expense, to protect Overlandlord, Sublandlord, any superior mortgagee or superior lessor (so long as Sublandlord provides 

  
 11 

 
Subtenant with the names and addresses of any such superior mortgagees or superior lessor), any other parties set forth in the Overlease, and any other parties whose names shall have been
furnished to Subtenant from time to time and Subtenant, as additional insureds, the insurance policies required to be held by “Tenant” under the applicable provisions of Section 17 of the Overlease, regardless of whether such
provisions have been incorporated herein, and such policies shall comply with the requirements of Section 17 of the Overlease, provided that Subtenant’s commercial general liability policy shall be required to cover only the Sublease
Premises, on the condition that Subtenant hereby covenants and represents that its commercial general liability policy will cover all liabilities of Subtenant and its officers, agents, representatives, and employees regardless of where in the
Building such individual’s liability arises or where the event related to such liability occurs. All commercial general liability insurance procured by Subtenant under this Section shall name Overlandlord, Sublandlord, any superior lessor, any
superior mortgagee, any other parties set forth in the Overlease, and any other parties whose names shall have been furnished to Subtenant from time to time, as their respective interests may appear as additional insureds (so long as Sublandlord
provides Subtenant with the names and addresses of such superior mortgagees or lessors). Subtenant shall be solely responsible for the payment of premiums for all such insurance policies. Duly executed certificates of insurance shall be delivered to
Sublandlord prior to the Commencement Date of this Sublease. Evidence of each renewal or replacement of a policy shall be delivered by Subtenant to Sublandlord at least thirty (30) days prior to the expiration of such policy, and Subtenant
shall cause the insurance carriers to agree to provide Overlandlord and Sublandlord with written notice thirty (30) days prior to the expiration of such policy if such policy has not been renewed or replaced. Subtenant shall not cause or permit
any action or condition that would invalidate or conflict with Overlandlord’s or Sublandlord’s insurance policies. 

(b)    Waivers of Subrogation. Subtenant shall include in each of its insurance policies (and, with respect to any
equipment in the Sublease Premises by Subtenant, in the insurance policies covering such equipment carried by Subtenant or the lessors of such equipment) against loss, damage or destruction by fire or other insured casualty a waiver of all of the
insurer’s rights of subrogation against Sublandlord, Overlandlord and any superior lessor. 
 23.    “As
Is” Condition. Subtenant expressly acknowledges and agrees that Sublandlord has not made and is not making, and Subtenant, in executing and delivering this Sublease, is not relying upon, any warranties, representations, promises or
statements, of Sublandlord, Overlandlord, or any other party except as specifically set forth herein. This Sublease and any other written agreement(s) made concurrently herewith are hereinafter referred to as the “Sublease
Documents.” It is understood and agreed that all understandings and agreements heretofore had between the parties with respect to the Sublease Premises are merged in the Sublease Documents, which alone fully and completely
express their agreements and that the same are entered into after full investigation, neither party relying upon any statement or representation not embodied in the Sublease Documents, made by the other. Except for the enclosure of the interior
stairs connecting the 12th and the 14th floors of the Overlease Premises (the “Demising Work”), Sublandlord is not required to perform work of any kind, nature or description to prepare the Sublease
Premises or any portion thereof for Subtenant’s occupancy, and Subtenant hereby accepts the Sublease Premises in their “as is” condition as of the Commencement Date. Sublandlord shall commence the Demising Work promptly following
receipt of Overlandlord’s consent to this Sublease and shall diligently prosecute such Demising Work to completion. 

  
 12 

 24.    End of Term. Upon the expiration or sooner termination of
the term of this Sublease, Subtenant shall vacate and surrender the Sublease Premises in accordance with Article 28 of the Overlease. 

25.    Alterations. (a) All alterations, changes, additions, improvements, repairs or replacements in, to, or
about the Sublease Premises (collectively, “Subtenant Changes”) shall be made in accordance with the provisions of the Overlease (as incorporated herein). No Subtenant Changes shall be effected by
Subtenant to the Sublease Premises without Sublandlord’s prior written consent. In addition, all Subtenant Changes shall be subject to Overlandlord’s consent, and Sublandlord makes no representations or warranties, and expresses no
opinion, with respect to Overlandlord’s consent to any Subtenant Changes. Any request for approval shall be in writing, delivered not less than fifteen (15) Business Days in advance of any proposed construction, and accompanied by plans,
specifications, bid proposals, work contracts and such other information concerning the nature and cost of the Subtenant Changes as may be reasonably requested by Sublandlord and/or Overlandlord, including the identities and mailing addresses of all
persons performing work or supplying materials. Sublandlord’s right to review plans and specifications and to monitor construction shall be solely for its own benefit, and Sublandlord shall have no duty to ensure that such plans and
specifications or construction comply with applicable laws. Subtenant shall cause, at is sole cost and expense, all Subtenant Changes to comply with insurance requirements and with Legal Requirements and shall implement at its sole cost and expense
any alteration or modification required by Legal Requirements and shall implement at its sole cost and expense any alteration or modification required by Legal Requirements as a result of any Subtenant Changes. Subtenant shall reimburse Overlandlord
and Sublandlord for all reasonable out-of-pocket costs and expenses (including reasonable attorneys’ fees) incurred in connection with the review of proposed
Subtenant Changes, including the plans with respect thereto. 
 (b)    If Sublandlord and Overlandlord, approve any
Subtenant Changes, Sublandlord and/or Overlandlord may impose such conditions on Subtenant in connection with the commencement, performance and completion of such Subtenant Changes as Sublandlord or Overlandlord may reasonably deem appropriate in
Sublandlord and/or Overlandlord’s reasonable discretion. Sublandlord and/or Overlandlord shall notify Subtenant at the time of approval of the Subtenant Changes whether such Subtenant Changes shall be required to be removed before the
expiration or earlier termination of this Sublease. If such Subtenant Change is required to be removed, it shall be removed by Subtenant at its sole cost and expense prior to the Expiration Date. Before Subtenant begins any Subtenant Changes,
Subtenant shall post on and about the Subleased Premises notices of non-responsibility pursuant to applicable law. Subtenant shall reimburse Sublandlord and/or Overlandlord for, and indemnify and hold
Sublandlord and Overlandlord harmless from any third party expense (including, without limitation, reasonable legal and consulting costs, and any amounts for which Sublandlord and/or Overlandlord become liable to other tenants or other third
parties, including without limitation, Governmental Authorities) incurred by Sublandlord and/or Overlandlord by reason of faulty work done by Tenant or its contractors, delays cause by such work, or inadequate cleanup that impacts the Building or
the Project, or Sublandlord or Overlandlord’s interest therein, or any tenant thereof. 

  
 13 

 (c)    Signage. Subtenant may install, at Subtenant’s sole
cost and expense, identifying signage on the 14th floor of the Building, subject to Sublandlord’s and Overlandlord’s prior approval of such signage and the requirements of the Overlease regarding installation of such identifying signage,
and provided that all such signage shall be removed by Subtenant at the end of the Sublease term and all damage caused by such removal shall be repaired and all improvements restored to the condition that existed prior to the installation of such
signage. 
 26.    Security Deposit. (a) On the date Subtenant executes this Sublease, Subtenant shall
deposit ONE HUNDRED SIXTY THOUSAND NINE HUNDRED FORTY AND 42/100 DOLLARS ($160,940.42) (the “Security Deposit”) as security for the performance and observance by Subtenant of the terms, covenants and
conditions of this Sublease. The Security Deposit need not be deposited in a separate account, but instead may be commingled with Sublandlord’s own funds. Sublandlord shall deposit the Security Deposit in an interest-bearing account and
interest accrued on the Security Deposit shall be annually paid to Subtenant at the end of the Sublease term if the Security Deposit is returned pursuant to this Sublease. Sublandlord shall have no liability for loss of the Security Deposit or any
interest as a result of any failure by the depositary. 
 (b)    If Subtenant defaults in the performance and observance
of any of the terms, covenants and conditions of this Sublease, Sublandlord may use, apply or retain the whole or any part of the Security Deposit to the extent required for the payment of any installment of Rent or Additional Rent as to which
Subtenant is in default or for any sum which Sublandlord may expend or may be required to expend by reason of Subtenant’s default in respect of any of the terms, covenants and conditions of this Sublease, including, without limitation, any
damages or deficiency in the reletting of the Sublease Premises, whether such damages or deficiency accrued before or after summary proceedings or other reentry by Sublandlord. In the case of every such use, application or retention of any such sum,
Subtenant on demand, shall pay to Sublandlord as Additional Rent the sum so used, applied or retained which shall be added to the Security Deposit so that the same shall be restored to its original amount. 

(c)    If Subtenant shall fully and faithfully comply with all the terms, covenants and conditions of this Sublease, the
Security Deposit shall be returned to Subtenant after the expiration date and delivery of exclusive possession of the Sublease Premises to Sublandlord. In the event of an assignment of Sublandiord’s rights under the Overlease, or any part
thereof which includes the Sublease Premises, Sublandlord shall transfer the Security Deposit to the assignee and Sublandlord shall be released by Subtenant from all liability for the return of such Security Deposit and Subtenant agrees to look
solely to the assignee for the return of the Security Deposit.] 
 27.    Indemnification. 

(a)    Notwithstanding anything to the contrary contained in this Sublease or the Overlease, Sublandlord shall not be
required to provide any of the indemnifications that Overlandlord has agreed to provide in the Overlease, whether or not specified in the Overlease or required by law, and “Sublandlord and Overlandlord” shall be substituted for
“Landlord” in the Overlease in the case of all of Subtenant’s indemnification obligations incorporated by reference. 

  
 14 

 (b)    Subtenant shall not do or permit any act or thing to be done upon
the Sublease Premises that may subject Sublandlord to any liability or responsibility for injury, damages to persons or property or to any liability by reason of any violation of any requirement of law, and shall exercise such control over the
Sublease Premises as to fully protect Sublandlord from and against any such liability. Subtenant shall defend, indemnify and save harmless Sublandlord, any partner, member, officer, trustee, director, shareholder, employee, representative,
contractor or agent of Sublandlord, Overlandlord, any mortgagee or superior lessor, and any other party that Sublandlord indemnifies under the Overlease, and their respective direct and indirect partners, members, shareholders, officers, employees,
agents and contractors (collectively, the “Indemnitees”) from and against all claims, actions, or proceedings (the “Claims”) of whatever nature, including
without limitation (i) any accident, injury or damages whatsoever to any person or to the property of any person and occurring during the term of this Sublease in or about the Sublease Premises, including as a result of any Subtenant Changes,
alterations, repairs or maintenance made by or on behalf of Sublandlord, (ii) any accident, injury or damage occurring outside of the Sublease Premises, but anywhere within or about the Building, where such accident, injury or damage results or
is claimed to have resulted from an act, omission or negligence of Subtenant or Subtenant’s agents, (iii) any breach, violation or nonperformance of any covenant, condition or agreement in this Sublease or the Overlease set forth and
contained on the part of Subtenant to be fulfilled, kept, observed and performed pursuant to this Sublease, (iv) any environmental claim relating in any way to Subtenant’s operation or use of the Sublease Premises or the Building,
(v) any mechanic’s or other lien or encumbrance or any action or proceeding brought thereon based upon an alteration or other repair, Subtenant Changes or services performed by or for Subtenant, (vi) any holding over by Subtenant
beyond the Expiration Date, (vii) the exercise by Subtenant or any party claiming by or through Subtenant of any rights against Overlandlord granted to Subtenant hereunder and (viii) Sublandlord’s failure or refusal to give its
approval to any proposed (x) Subtenant Changes or (y) assignment or sublease, including claims that may be made against Sublandlord by the proposed sub-subtenant or assignee or by any broker or other
persons claiming a commission or similar compensation in connection with the proposed assignment or subletting. This indemnity and hold harmless agreement shall indemnify the Indemnitees from and against any and all obligations (including without
limitation studies, assessments, removal, mitigating and remedial actions), losses, claims, suits, judgments, liabilities, fines, penalties, damages, actual
out-of-pocket costs and expenses (including without limitation actual out-of-pocket
reasonable attorneys’ and consultants’ fees and expenses) of any kind or nature incurred in or in connection with any such Claim brought thereon and the defense thereof, except to the extent such Claim is a result of the Indemnitees’
own gross negligence or willful misconduct. If any Claim is made or brought against any Indemnitee, which Claim Subtenant shall be obligated to indemnify such Indemnitee against, then, upon demand by such Indemnitee, Subtenant, at its sole expense,
shall resist or defend such Claim in the Indemnitee’s name, if necessary, by such attorneys as such Indemnitee shall reasonably approve. The provisions of this Section 27 shall survive the Expiration Date or sooner termination of this
Sublease. 
 28.    Sublandlord’s Liability; Limitations Thereon. 

(a)    Notwithstanding anything to the contrary in this Sublease or in any other document or instrument executed in
connection with the transactions described herein, Sublandlord is currently constituted as a corporation and Sublandlord shall be liable for the 

  
 15 

 performance of the duties, responsibilities, liabilities and obligations of Sublandlord under, with respect
to or arising out of this Sublease to the extent (but only to the extent) of the assets of Sublandlord (which term “assets” as used in this Section 28 shall include, without limitation, fixed assets,
furnishings, fixtures, equipment, cash, investments, accounts receivable and accrued charges for work in process), except that Sublandlord’s assets shall specifically exclude the assets of any of the past, present or future partners, members,
shareholders and other owners of equity in Sublandlord (as Sublandlord is now, or may hereafter be, constituted) or the individual entities or persons who, directly or indirectly, own an interest in any such entity that is a corporation or legal
entity (individually, a “Sublandlord Owner” and collectively, “Sublandlord Owners”): The provisions of this Section 28 shall not however, (a) constitute a waiver,
release or impairment of any obligations of Sublandlord under this Sublease; or (b) impair Subtenant’s rights to realize upon the assets of Sublandlord not expressly excluded by the terms of this Section 28 for recovery of any
judgment. 
 (b)    Subtenant further acknowledges and agrees that, in the event of any insolvency, bankruptcy,
receivership, custodianship, liquidation, reorganization, assignment for the benefit of creditors or other proceeding for the liquidation, dissolution or other winding up of Sublandlord or any of its properties, Subtenant shall not receive or be
entitled to receive, directly or indirectly, any payments from or any distributions or redistributions of any of the excluded assets described in Section 28(a) or any proceeds thereof (whether in cash or other property), whether payable under
the terms of any plan or reorganization, by any receiver, trustee, liquidator, custodian, conservator or any other person having authority to effect any such payment or otherwise. 

29.    Anti-Terrorism Representations. 

(a)    Sublandlord represents and warrants to Subtenant that (1) neither Sublandlord, its constituents or affiliates
nor any of their respective agents (collectively, “Sublandlord Parties”) are in violation of any law relating to terrorism or money laundering, including but not limited to, Executive Order No. 13224 on Terrorist
Financing, the U.S. Bank Secrecy Act, as amended by the Patriot Act, the Trading with the Enemy Act, the International Emergency Economic Powers Act and all regulations promulgated thereunder, all as amended from time to time (collectively,
“Anti-Terrorism Law”); (2) no action, proceeding, investigation, charge, claim, report, or notice has been filed, commenced, or threatened against any of the Sublandlord Parties alleging any violation of any Anti-Terrorism Law; (3) none of the Sublandlord Parties has, after due inquiry, knowledge of any fact, event, circumstance, situation or condition which could reasonably be expected to result in any action,
proceeding, investigation, charge, claim, report, notice, or penalty being filed, commenced, threatened or imposed against any of them relating to any violation of or failure to comply with any Anti-Terrorism Law; (4) none of the Sublandlord
Parties is a “Prohibited Person”. As used in this Sublease, “Prohibited Person” shall mean any (1) person or entity who is on the OFAC List or any “designated national,” “specially designated
national,” “specially designated terrorist,” “specially designated global terrorist,” “foreign terrorist organization,” “blocked person,” or “specially designated narcotics trafficker,” within
the definitions set forth in the Foreign Assets Control Regulations of the United States Treasury Department, 31 C.F.R., Subtitle B, Chapter V, as amended; (2) any government or entity against whom the United States maintains economic or other
sanctions or embargoes under the Regulations of the United States Treasury Department, 

  
 16 

 
31 C.F.R., Subtitle B, Chapter V, or the Export Administration Regulations of the United States Department of Commerce, 15 C.F.R. Subtitle B, Chapter VII, Subchapter C, each as amended,
including, but not limited to, the “Government of Burma,” the “Government of Sudan,” the “Taliban,” and the “Government of Iran,” and person acting on behalf of such government or entity; (3) person or
entity who is listed in the Annex to or is otherwise within the scope of Executive Order 13224 - Blocking Property and Prohibiting Transactions with Persons who Commit, Threaten to Commit, or Support Terrorism, effective September 24, 2001; or
(4) person or entity subject to additional restrictions imposed by any of the following statutes or Regulations and Executive Orders issued thereunder: the Trading with the Enemy Act, 50 U.S.C. Appendix, §§ 1 et seq.;
the Iraq Sanctions Act, §§ 586 et seq. of Pub. L. 101-513, 104 Stat. 2047; the National Emergencies Act, 50 U.S.C. §§ 1601 et seq.; the Anti-Terrorism and Effective
Death Penalty Act of 1996, Pub. L. 104-132, 110 Stat. 1214; the International Emergency Economic Powers Act, 50 U.S.C. §§ 1701 et seq.; the United Nations Participation Act, 22 U.S.C. §
287c; the International Security and Development Cooperation Act, 22 U.S.C. § 2349aa-9; the Nuclear Proliferation Prevention Act of 1994, Pub. L. 103-236, 108 Stat.
507; the Foreign Narcotics Kingpin Designation Act, 21 U.S.C. §§ 1901 et seq.; the Iran and Libya Sanctions Act of 1996, Pub. L. 104-172, 110 Stat. 1541; the Cuban Democracy Act, 22
U.S.C. §§ 6001 et seq.; the Cuban Liberty and Democratic Solidarity Act, Pub. L. 104-114, 22 U.S.C. §§ 6021 et seq.; the Clean Diamonds Trade Act, Pub. L. 108-19, 117 Stat. 631; the Burmese Freedom and Democracy Act, Pub. L. 108-61, 117 Stat. 864; the Foreign Operations, Export Financing and Related Programs Appropriations Act
of 1997, § 570 of Pub. L. 104-208, 110 Stat. 3009; the Trade Sanctions Reform and Enhancement Act of 2000, Title IX of Pub. L. 106-387, 114 Stat. 1549; the Uniting
and Strengthening America by Providing Appropriate Tools Required to Intercept and Obstruct Terrorism Act of 2001, Pub. L. 107-56, 115 Stat. 272; or any other law of similar import as to any non-U.S. country, as each such Act or law has been or may be amended, adjusted, modified, or reviewed from time to time. Sublandlord covenants that it shall not knowingly (1) conduct any business or transaction
or make or receive any contribution of funds, goods or services in violation of any Anti-Terrorism Law or (2) engage in or conspire to engage in any transaction that evades or avoids, has the purpose of evading or avoiding or attempts to
violate any of the prohibitions of any Anti-Terrorism Law. Sublandlord agrees promptly to deliver to Subtenant any certification or other reasonable evidence requested from time to time by Subtenant, in its reasonable discretion, confirming
Sublandlord’s compliance with the foregoing requirements. 
 (b)    Subtenant represents and warrants to
Sublandlord that (1) neither Subtenant, its constituents or affiliates, nor any of their respective agents (collectively, “Subtenant Parties”) are in violation of any Anti-Terrorism Law and (2) no Subtenant Party is
a Prohibited Person. Subtenant covenants that it shall not knowingly (1) conduct any business or transaction or make or receive any contribution of funds, goods or services in violation of any Anti-Terrorism Law or (2) engage in or
conspire to engage in any transaction that evades or avoids, has the purpose of evading or avoiding or attempts to violate any of the prohibitions of any Anti-Terrorism Law. Subtenant agrees promptly to deliver to Sublandlord any certification or
other reasonable evidence requested from time to time by Sublandlord, in its reasonable discretion, confirming Subtenant’s compliance with the foregoing requirements. 

30.    Miscellaneous. This Sublease is made in the State of New York and shall be governed by and construed under
the laws thereof. This Sublease supersedes any and all 

  
 17 

 
other or prior understandings, agreements, covenants, promises, representations or warranties of or between the parties (which are fully merged herein) with respect to the Sublease Premises and
the subject matter hereof. The headings in this Sublease are for purposes of reference only and shall not limit or otherwise affect the meaning hereof. This Sublease shall not be binding upon either party for any purpose whatsoever unless and until
Sublandlord has delivered to Subtenant a fully executed copy hereof. 

  
 18 

 IN WITNESS WHEREOF, Sublandlord and Subtenant have duly executed this Sublease as of the day
and year first written above. 
  

			
	Sublandlord:
	
	IMCLONE SYSTEMS LLC,
	a Delaware limited liability company
		
	By:	 	 /s/ Stephen L. Van Soelen

		 	Name: Stephen L. Van Soelen
		 	Title: Senior Director, Strategic Real Estate
	
	Subtenant:
	
	MEIRAGTX, LLC,
	a Delaware limited liability company
		
	By:	 	 /s/ Richard Giroux

		 	Name: Richard Giroux
		 	Title: Chief Financial Officer

  
 19EX-10.3

 Exhibit 10.3 
  

 
 Dated 29th May 2019 

Agreement for Lease with Landlord’s Refurbishment Works 

relating to 34-38 Provost Street London N1 7NG 

 

	(1)	 Provost 1 Limited and Provost 2 Limited 

 

	(2)	 Meiragtx UK II Limited 

 

			
	Harbottle & Lewis LLP	  	T + 44 (0)20 7667 5000
	Hanover House	  	F + 44 (0)20 7667 5100
	14 Hanover Square	  	www.harbottle.com
	London	  	DX 44617 Mayfair
	W1S 1HP	  	
		
	Ref: 145/319442/3	  	

 CONTENTS 
  

 
 CLAUSE 

 

							
	 1.  Interpretation
	  	 	3	 
	 2.  Agreement for lease
	  	 	7	 
	 3.  Tenant’s Works
	  	 	7	 
	 4.  Timetable for engrossments
	  	 	8	 
	 5.  Exclusion of security of tenure
	  	 	8	 
	 6.  Landlord’s Works
	  	 	8	 
	 7.  Practical Completion and Rectification Period
	  	 	9	 
	 8.  Long Stop Date
	  	 	11	 
	 9.  Insurance
	  	 	11	 
	 10.  Damage after Practical Completion
	  	 	12	 
	 11.  Measurement
	  	 	12	 
	 12.  Rent and Target Area
	  	 	13	 
	 13.  Landlord’s obligations
	  	 	13	 
	 14.  Conditions
	  	 	13	 
	 15.  Vacant possession
	  	 	14	 
	 16.  Deducing title
	  	 	14	 
	 17.  Title guarantee
	  	 	15	 
	 18.  Matters affecting the Property
	  	 	15	 
	 19.  Termination on Tenant’s insolvency
	  	 	16	 
	 20.  Consequences of termination
	  	 	16	 
	 21.  Completion of grant of the lease
	  	 	17	 
	 22.  Registration
	  	 	18	 
	 23.  VAT
	  	 	18	 
	 24.  Entire agreement
	  	 	18	 
	 25.  Joint and several liability
	  	 	19	 
	 26.  Notices
	  	 	19	 
	 27.  Third party rights
	  	 	21	 
	 28.  Governing law
	  	 	21	 
	 29.  Jurisdiction
	  	 	21	 
		
	 ANNEX
	  			
		
	 ANNEX A Approved Documents in agreed form
	  	 	23	 

  
 1 

							
	 ANNEX B
	 	List of parties required to give Collateral Warranties	  	 	24	 
	 ANNEX C
	 	Agreed forms of Collateral Warranties	  	 	25	 
	 ANNEX D
	 	Agreed form of Lease	  	 	26	 
	 ANNEX E
	 	Agreed form of Licence for Alterations	  	 	27	 
	 ANNEX F
	 	Agreed form of Rent Deposit Deed	  	 	28	 

  
 2 

			
	This agreement is dated 29th May	  	2019

 Parties 
  

	(1)	 PROVOST 1 LIMITED incorporated and registered in England and Wales with company number 11228901 and
PROVOST 2 LIMITED incorporated and registered in England and Wales with company number 11228852 both of whose registered office is at 64 New Cavendish Street London W1G 8TB (Landlord) 

 

	(2)	 MEIRAGTX UK II LIMITED incorporated and registered in England and Wales with company number 09348737
whose registered office is at 92 Britannia Walk London N1 7NQ (Tenant) 

 BACKGROUND 

 

	(A)	 The Landlord owns the freehold of the Property and has agreed to grant the Tenant a Lease of the Property on
the terms contained in this agreement. 

  

	(B)	 The Lease shall contain an agreement between the Landlord and the Tenant that the provisions of sections 24-28 of the Landlord and Tenant Act 1954 will be excluded in relation to the tenancy to be created by the Lease. 

  

	(C)	 The Landlord has agreed to undertake certain works at the Property before the grant of the Lease and the Tenant
wishes to carry out fitting out works. 

 Agreed terms 
  

	1.	 Interpretation 

The following definitions and rules of interpretation apply in this agreement. 

 

	1.1	 Definitions: 

Approved Documents: all plans, specifications, drawings, engineering calculations, bills of quantity and other data for the
Landlord’s Works in the agreed form annexed to this agreement including (where applicable): 
  

	 	a)	 any variations or amendments that may be agreed by the Landlord and the Tenant from time to time in accordance
with clause 6.4; and 

  

	 	b)	 any minor variations permitted under clause 6.5. 

Building Contract: a building contract for the Landlord’s Works dated 24 November 2018 between the Landlord and the Building
Contractor.  
 Building Contractor: Thirdway Contracts Limited or such other suitably experienced and competent building
contractor as may be appointed by the Landlord to carry out the Landlord’s Works, together with any replacement building contractor that may be appointed by the Landlord in accordance with the terms of the Building Contract.  

  
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 Certificate of Making Good: the Contract Administrator’s certificate or written
statement issued in accordance with the Building Contract certifying that any defects, shrinkages or faults appearing in the Landlord’s Works during the Rectification Period and for which the Building Contractor was responsible under the
Building Contract have been made good.  
 Collateral Warranties: deeds of collateral warranty from the parties identified in
the relevant annex to this agreement.  
 Condition: any one of the Part 1 Conditions.  

Contract Administrator: Paul Willis of Constructive Management or such other person as may be appointed as a replacement contract
administrator for the time being by the Landlord (acting reasonably) in relation to this agreement and the Building Contract. 

Contract Rate: 4% per annum above the base rate from time to time of Barclays Bank Plc.  

Electronic Payment: payment by electronic means in same day cleared funds from an account held in the name of the Landlord’s
Conveyancer or Tenant’s Conveyancer (as applicable) at a clearing bank to an account in the name of the Tenant’s Conveyancer or Landlord’s Conveyancer (as applicable). 

Event of Default: any of the events set out in clause 19.1.  

Internal Area: the net internal floor area in square feet of the Property calculated in accordance with the latest RICS Code of
Measuring Practice.  
 Landlord’s Conveyancer: Harbottle & Lewis LLP of 14 Hanover Square London W1S 1HP Fax:
0207 667 5100 Ref: 145/319442/3 or any other conveyancer whose details have been given by notice from time to time by the Landlord to the Tenant. 

Landlord’s Works: the works to be carried out by the Landlord at the Property before the grant of the Lease as shown in the
Approved Documents.  
 Lease: a lease in the agreed form annexed to this agreement.  

Lease Completion Date: the day that is 5 working days after the Practical Completion Date.  

Licence for Alterations: a licence between the Landlord and Tenant in the agreed form annexed to this agreement.  

Long Stop Date:                    
2019 [6 months]. 
 LTA 1954: Landlord and Tenant Act 1954. 

Measurement Surveyor: the independent measurer apportioned under clause 11. 

  
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 Part 1 Conditions: part 1 of the Standard Commercial Property Conditions (Third
Edition - 2018 Revision).  
 Part 2 Conditions: part 2 of the Standard Commercial Property Conditions (Third Edition - 2018
Revision).  
 Planning Permission: the planning permission dated 6 April 2018 from the London Borough of Hackney under
reference 2017/4783 together with all requisite approvals already issued in connection with it and any waivers, relaxations or variations of any of its terms.  

Practical Completion Certificate: the Contract Administrator’s certificate or written statement issued in accordance with the
Building Contract certifying that the Landlord’s Works are practically complete according to the terms of the Building Contract and setting out the date on which practical completion occurred.  

Practical Completion Date: the date stated in the Practical Completion Certificate. 

Property: the property at 34-38 Provost Street London N1 7NG as more particularly defined in the
Lease.  
 President: the President for the time being of the Royal Institution of Chartered Surveyors.  

Rectification Period: the defects liability period or rectification period for the making good of defects, shrinkages or other faults in
the Landlord’s Works under the Building Contract.  
 Rent: the initial rent per annum (subject to review) exclusive of
VAT payable under the Lease and calculated in accordance with clause 12.  
 Rent Commencement Date: four months after the
Lease Completion Date.  
 Rent Deposit Deed: a rent deposit deed in the agreed form annexed to this agreement.  

Rent Payment Dates: 25 March, 24 June, 29 September and 25 December. 

Requisite Consents: building regulation approvals, by-law approvals, and any other consents,
licences and authorisations required from any competent authority, statutory undertaker or person for the carrying out of the Landlord’s Works.  

Target Area: 11,306 square feet being the anticipated Internal Area.  

Target Date: 17 June 2019 (as may be extended in accordance with clause 6.2).  

Tenant’s Conveyancer: Russel Cooke of 8 Bedford Row London WC1R 4BX Ref: 22/PXN/173748/1 or any other conveyancer whose details
have been given by notice from time to time by the Tenant to the Landlord.  
 Tenant’s Surveyor: [NAME, ADDRESS, FAX
NUMBER, REFERENCE] or any other surveyor whose details may be given in writing from time to time by the Tenant to the Landlord.  

  
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 Tenant’s Works: the fitting out works to be carried out by the Tenant at the
Property as described in the Licence for Alterations.  
 VAT: value added tax or any equivalent tax chargeable in the UK. 

 Written Replies: are: 
  

	 	a)	 written replies that the Landlord’s Conveyancer has given prior to exchange of this agreement to any
written enquiries raised by the Tenant’s Conveyancer; or 

  

	 	b)	 written replies to written enquiries given prior to exchange of this agreement by the Landlord’s
Conveyancer to the Tenant’s Conveyancer. 

  

	1.2	 Clause, Schedule and paragraph headings shall not affect the interpretation of this agreement.

  

	1.3	 A person includes a natural person, corporate or unincorporated body (whether or not having separate
legal personality). 

  

	1.4	 The Schedules form part of this agreement and shall have effect as if set out in full in the body of this
agreement. Any reference to this agreement includes the Schedules. 

  

	1.5	 A reference to a company shall include any company, corporation or other body corporate, wherever and
however incorporated or established. 

  

	1.6	 Unless the context otherwise requires, words in the singular shall include the plural and in the plural shall
include the singular. 

  

	1.7	 Unless the context otherwise requires, a reference to one gender shall include a reference to the other
genders. 

  

	1.8	 A reference to a statute or statutory provision is a reference to it as amended, extended or re-enacted from time to time. 

  

	1.9	 A reference to a statute or statutory provision shall include all subordinate legislation made from time to
time under that statute or statutory provision. 

  

	1.10	 Except in relation to clause 1.17 a reference to writing or written includes fax but not email.

  

	1.11	 A reference to this agreement or to any other agreement or document referred to in this agreement is a
reference to this agreement or such other agreement or document as varied or novated (in each case, other than in breach of the provisions of this agreement) from time to time. 

  
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	1.12	 Unless the context otherwise requires, references to clauses, Schedules and Annexes are to the clauses,
Schedules and Annexes of this agreement and references to paragraphs are to paragraphs of the relevant Schedule. 

  

	1.13	 Any words following the terms including, include, in particular, for example or any
similar expression shall be construed as illustrative and shall not limit the sense of the words, description, definition, phrase or term preceding those terms. 

 

	1.14	 Any obligation on a party not to do something includes an obligation not to allow that thing to be done.

  

	1.15	 Unless this agreement otherwise expressly provides, a reference to the Property or the
Landlord’s Works is to the whole and any part of them. 

  

	1.16	 Any reference to the Landlord’s consent or approval being required is to a consent or approval in writing
which must be obtained before the relevant act is taken or event occurs. 

  

	1.17	 For the purposes of the definition of Written Replies, written replies and written enquiries include any pre-contract enquiries and any replies to pre-contract enquiries that are requested or given by reference to the CPSE1 and CPSE3 and include enquiries or replies so requested
or given by email. 

  

	2.	 Agreement for lease 

 

	2.1	 In consideration of the Tenant’s obligations under this agreement, the Landlord shall grant to the Tenant
and the Tenant shall accept from the Landlord the Lease on the terms set out in this agreement. No purchase price, premium, or deposit is payable. 

  

	2.2	 The Tenant cannot require the Landlord to grant the Lease to any person other than the Tenant (here meaning
Meiragtx UK II Limited, incorporated and registered in England and Wales with company number 09348737, only). 

  

	2.3	 The Tenant cannot assign, sublet, charge, or otherwise share or part with the benefit of this agreement whether
in relation to the whole or any part of the Property. 

  

	2.4	 Conditions 1.4, 3.2 and 9.8.3 do not apply to this agreement. 

 

	3.	 Tenant’s Works 

 

	3.1	 The Tenant shall not be permitted access to the Property to carry out any of the Tenant’s Works prior to
the grant of the Lease. 

  
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	3.2	 The Landlord and the Tenant shall enter into the Licence for Alterations immediately following completion of
the grant of the Lease. 

  

	4.	 Timetable for engrossments 

 

	4.1	 The Landlord’s Conveyancer shall send the engrossed counterpart Lease and counterpart Licence for
Alterations and Rent Deposit Deed to the Tenant’s Conveyancer by two working days after the Practical Completion Date. 

  

	4.2	 The Tenant shall execute the counterpart Licence for Alterations and deliver it to the Landlord’s
Conveyancer on completion. 

  

	4.3	 Condition 11.2.5 does not apply to this agreement. 

 

	4.4	 Condition 11.2.6 is amended so that reference to seller is reference to the Landlord’s conveyancer.

  

	5.	 Exclusion of security of tenure 

 

	5.1	 The parties confirm that: 

 

	 	(a)	 the Landlord served a notice on the Tenant, as required by section 38A(3)(a) of the LTA 1954 and which applies
to the tenancy to be created by the Lease, before this agreement was entered into; and (b) [[NAME OF DECLARANT], who was duly authorised by the Tenant to do so], made a statutory declaration dated 2019 in accordance with the requirements of section
38A(3)(b) of the LTA 1954. 

  

	6.	 Landlord’s Works 

 

	6.1	 The Landlord shall apply for and use reasonable endeavours to obtain the Requisite Consents.

  

	6.2	 The Landlord shall use reasonable endeavours to procure that the Practical Completion Date occurs by the Target
Date which shall be extended commensurate with any extensions of time: 

  

	 	(a)	 allowed by the Contract Administrator under the terms of the Building Contract; and/or 

 

	 	(b)	 certified by the Contract Administrator as being fair and reasonable, having regard to the delay in question,
where completion of the Landlord’s Works is delayed due to an event or cause that is beyond the Landlord’s reasonable control. 

  
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	6.3	 The Landlord shall use reasonable endeavours to procure that the Landlord’s Works are carried out:

  

	 	(a)	 with due diligence and in a good and workmanlike manner; 

 

	 	(b)	 using only good quality materials and well-maintained plant; 

 

	 	(c)	 in accordance with this agreement, the Approved Documents, the Planning Permission and the Requisite Consents;

  

	 	(d)	 in accordance with all statutory or other legal requirements and the recommendations or requirements of the
local authority or statutory undertakings; 

  

	 	(e)	 in compliance with all relevant British Standards, codes of practices and good building practice; and

  

	 	(f)	 by selecting and using materials so as to avoid known hazards to the health and safety of any person and to
ensure the long term integrity of the Property. 

  

	6.4	 The Landlord shall not, (subject to clause 6.5), vary, alter, add to or remove anything from the Approved
Documents without the Tenant’s consent (such consent not to be unreasonably withheld or delayed). 

  

	6.5	 The Landlord may make minor variations to the Approved Documents without the Tenant’s consent provided
that: 

  

	 	(a)	 the variations are insubstantial and immaterial; 

 

	 	(b)	 the variations are in accordance with the Planning Permission, the Requisite Consents and any statutory
requirements; 

  

	 	(c)	 any substitute materials used are of an equal or better quality and suitability to those originally specified;

  

	 	(d)	 the variations do not delay the completion of the Landlord’s Works; 

 

	 	(e)	 the variations are required by any local or competent authority or statutory undertaking as a condition of the
grant or continuance of any of the Requisite Consents; and/or 

  

	 	(f)	 the variations do not materially impact on the Tenant’s likely use and enjoyment of the Property.

  

	7.	 Practical Completion and Rectification Period 

 

	7.1	 The Landlord shall procure that the terms of the Contract Administrator’s professional appointment require
the Contract Administrator to act impartially when exercising the power to issue certificates and award extensions of time under the Building Contract and this agreement. 

  
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	7.2	 The Landlord shall procure that the Contract Administrator: 

 

	 	(a)	 gives at least 5 working days’ notice to the Tenant of the Contract Administrator’s intention to
inspect the Landlord’s Works for the purpose of issuing the Practical Completion Certificate and allows the Tenant and the Tenant’s Surveyor to attend the inspection and make representations either during the inspection or in writing
immediately thereafter; and 

  

	 	(b)	 without fettering the discretion of the Contract Administrator in carrying out duties under the Building
Contract, takes proper account of any representations that are made in accordance with sub-clause (a) when considering whether to issue the Practical Completion Certificate in accordance with the terms of
the Building Contract. 

  

	7.3	 The Landlord shall procure that the Contract Administrator gives a copy of the Practical Completion Certificate
to the Tenant as soon as practicable after its issue together with a copy of any accompanying snagging list. 

  

	7.4	 The issue of the Practical Completion Certificate shall be conclusive evidence binding on the parties that the
Landlord’s Works have been completed in accordance with the terms of this agreement, subject to the Landlord’s obligations during the Rectification Period. 

 

	7.5	 The Landlord shall use reasonable endeavours to enforce the Building Contractor’s obligations under the
Building Contract to remedy any defects, shrinkages or faults appearing in the Landlord’s Works during the Rectification Period. 

  

	7.6	 During the Rectification Period, the Tenant or the Tenant’s Surveyor may make written representations to
the Contract Administrator identifying defects, shrinkages or faults in the Landlord’s Works which the Building Contractor is obliged to remedy in accordance with the Building Contract. Without fettering the discretion of the Contract
Administrator in carrying out duties under the Building Contract, the Landlord shall use reasonable endeavours to ensure that the Contract Administrator takes proper account of any such representations. 

 

	7.7	 The Landlord shall procure that the Contract Administrator: 

 

	 	(a)	 gives at least 5 working days’ notice to the Tenant of the Contract Administrator’s intention to
inspect the Landlord’s Works for the purpose of issuing the Certificate of Making Good and allows the Tenant and the Tenant’s Surveyor to attend the inspection and make representations either during the inspection or in writing immediately
thereafter; and 

  

	 	(b)	 without fettering the discretion of the Contract Administrator in carrying out duties under the Building
Contract, takes proper account of any representations that are made in accordance with clause (a) when considering whether to issue the Certificate of Making Good in accordance with the terms of the Building Contract. 

  
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	7.8	 The Landlord shall procure that the Contract Administrator gives a copy of the Certificate of Making Good to
the Tenant as soon as practicable after its issue. 

  

	7.9	 The Landlord shall use reasonable endeavours to procure the grant of the Collateral Warranties in favour of the
Tenant prior to the Lease Completion Date. 

  

	8.	 Long Stop Date 

If the Practical Completion Date has not occurred by 5.00 pm on the Long Stop Date, either the Landlord or the Tenant may, at any time after
the Long Stop Date but before the Practical Completion Date, give written notice to the other that, unless the Practical Completion Date occurs within 20 working days of the receipt of that notice (time being of the essence), it may terminate this
agreement. If the Practical Completion Date does not occur within 20 working days of receipt of that notice then it may, by further written notice terminate this agreement with immediate effect. 

 

	9.	 Insurance 

  

	9.1	 From the date of this agreement until the Practical Completion Date, the Landlord shall insure or shall procure
that the Building Contractor insures the Landlord’s Works, the Property and all plant and unfixed materials and goods delivered to or placed on or adjacent to the Property and intended for incorporation in the Landlord’s Works against all
perils resulting in loss or damage thereto on customary contractors’ all risks terms: 

  

	 	(a)	 in the joint names of the Landlord and the Building Contractor; and 

 

	 	(b)	 for not less than their full reinstatement value (taking into account the progress of the Landlord’s
Works) together with all site clearance and professional fees incurred in connection with such reinstatement. 

  

	9.2	 In the event of any loss or damage occurring before the Practical Completion Date to the Landlord’s Works,
the Property, plant, materials or goods so insured, the Landlord shall use reasonable endeavours to procure that their reinstatement or replacement is carried out diligently and with all reasonable speed. The Landlord shall apply the proceeds of the
insurance towards such reinstatement or replacement. 

  

	9.3	 The Landlord and the Tenant mutually agree not knowingly to do or permit anything to be done that may render
any insurance policy void or voidable. 

  

	9.4	 Conditions 8.1, 8.2.1, 8.2.2, 8.2.3, 8.2.4(b), 8.2.5(b) and 8.2.7 do not apply to this agreement.

  
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	10.	 Damage after Practical Completion 

 

	10.1	 The Tenant shall not be entitled to refuse to complete or to delay completion of the grant of the Lease due to
any event occurring after the Practical Completion Date that results in: 

  

	 	(a)	 any damage to the Property or any part of it; or 

 

	 	(b)	 any damage to the means of access to the Property; or 

 

	 	(c)	 any deterioration in the Property’s condition. 

 

	10.2	 The provisions in the Lease relating to insurance of the Property shall apply from the Practical Completion
Date. 

  

	11.	 Measurement 

  

	11.1	 When the Landlord reasonably considers the Property is properly capable of measurement, the Landlord and Tenant
shall use all reasonable endeavours to agree the Internal Area and failing agreement the Landlord shall instruct the Measurement Surveyor as soon as reasonably practicable to determine the Internal Area in accordance with the terms of this
agreement. 

  

	11.2	 The Measurement Surveyor shall be Plowman Craven or if they refuse or are incapable of acting such other firm
with expertise in measuring property of a nature similar to the Property, as the Landlord and Tenant may agree or as may, in default of agreement, be nominated by the President or his nominee on the application of either the Landlord or the Tenant.

  

	11.3	 In measuring the Internal Area, the Measurement Surveyor shall be instructed to: 

 

	 	(a)	 assume that the Tenant’s Works and any other works carried out by or on behalf of the Tenant have not been
carried out; and 

  

	 	(b)	 reflect the final layout of the Property arising from the carrying out and completion of the Landlord’s
Works in accordance with the terms of this agreement. 

  

	11.4	 The determination of the Internal Area by the Measurement Surveyor shall be final and binding on the Landlord
and Tenant (save in the case of manifest error or fraud). 

  

	11.5	 The Landlord and Tenant agree that the appointment of the Measurement Surveyor shall be on terms reasonably
satisfactory to the Landlord and the Tenant (including provision of a duty of care warranty or other form of contractual reliance to the Tenant). 

  
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	11.6	 The proper costs charged by the Measurement Surveyor pursuant to this agreement shall be borne by the Landlord.

  

	12.	 Rent and Target Area 

 

	12.1	 Subject to clause 12(a), the initial rent per annum (subject to review) exclusive of VAT payable under the
Lease shall be calculated in accordance with the following formula: 

 A x B 

Where: 
 A is the Internal
Area as agreed or determined in accordance with this agreement; and 
 B is sixty pounds and fifty pence (£60.50). 

 

	12.2	 If the Internal Area as agreed or determined in accordance with this agreement is more than 10% greater than
the Target Area or more than 10% smaller than the Target Area the Tenant shall be entitled to terminate this agreement by giving written notice to the Landlord within three working days of the agreement or final determination of the Internal Area in
accordance with this agreement (time being of the essence). 

  

	13.	 Landlord’s obligations 

 

	13.1	 The obligations in clause 6, clause 7, and clause 9 are personal and binding only on Provost 1 Limited and
Provost 2 Limited, incorporated and registered in England and Wales with company numbers 11228901 and 11228852 respectively. 

  

	13.2	 Provost 1 Limited and Provost 2 Limited shall be released from all liability in respect of its obligations
referred to in clause 13.1 after a period of six months after the Practical Completion Date, except in relation to any claim made against or of which it is given notice prior to the end of that period. 

 

	14.	 Conditions 

  

	14.1	 The Part 1 Conditions are incorporated in this agreement, in so far as they: 

 

	 	(a)	 are applicable to the grant of a lease; 

 

	 	(b)	 are not inconsistent with the other clauses in this agreement; and 

 

	 	(c)	 have not been modified or excluded by any of the other clauses in this agreement. 

 

	14.2	 The terms used in this agreement have the same meaning when used in the Part 1 Conditions.

  
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	14.3	 The Part 2 Conditions are not incorporated in this agreement. 

 

	14.4	 The following Conditions are amended: 

 

	 	(a)	 Condition 1.1.1(c) so that reference to “clearing bank” means a bank which is a direct participant in
the CHAPS system operated by the Bank of England. 

  

	 	(b)	 Condition 1.1.1(d) so that reference to completion date in Condition 1.1.1(d) is to the Lease Completion Date
as defined by this agreement. 

  

	 	(c)	 Condition 1.1.1(e) so that reference to contract rate in Condition 1.1.1(e) is to the Contract Rate as defined
by this agreement. 

  

	 	(d)	 Condition 1.1.1(o) so that reference to VAT in Condition 1.1.1(o) is to VAT as defined by this agreement.

  

	14.5	 Condition 1.1.4(a) does not apply to this agreement. 

 

	14.6	 Condition 9.1.1 is amended so that the words “completion date is twenty working days after the date of
completion but” are deleted. 

  

	14.7	 Condition 11.2.2 is amended to include the words: “(d) “transfer” includes the grant of a
lease.” 

  

	15.	 Vacant possession 

 

	15.1	 The Landlord shall give the Tenant vacant possession of the Property on completion of the grant of the Lease.

  

	15.2	 The Tenant is not entitled to and shall not be permitted to take occupation or possession of the Property or of
any part of it prior to completion of the grant of the Lease and this agreement does not operate as a demise. 

  

	16.	 Deducing title 

 

	16.1	 The Landlord’s freehold title to the Property has been deduced to the Tenant’s Conveyancer before the
date of this agreement. 

  

	16.2	 The Tenant is deemed to have full knowledge of the Landlord’s title and is not entitled to raise any
objection, enquiry or requisition in relation to the Landlord’s title save the usual pre-completion requisitions on title and/or arising from the usual completion searches at the Land Registry.

  

	16.3	 Conditions 7.1, 7.2, 7.3, 7.4.2, 11.2.4, and 11.3 do not apply to this agreement. 

  
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	17.	 Title guarantee 

 

	17.1	 Subject to the other provisions of this clause, the Landlord shall grant the Lease with full title guarantee.

  

	17.2	 The implied covenants for title are modified so that: 

 

	 	(a)	 the covenant set out in section 2(1)(b) of the Law of Property (Miscellaneous Provisions) Act 1994 shall not
extend to costs arising from the Tenant’s failure to: 

  

	 	(i)	 make proper searches; or 

 

	 	(ii)	 raise requisitions on title or on the results of the Tenant’s searches; and 

 

	 	(b)	 the covenant set out in section 3(3) of the Law of Property (Miscellaneous Provisions) Act 1994 shall extend
only to charges or encumbrances created by the Landlord. 

  

	17.3	 Conditions 7.6.2 and 7.6.4 do not apply to this agreement. 

 

	17.4	 Condition 12 does not apply to this agreement. 

 

	18.	 Matters affecting the Property 

 

	18.1	 The Landlord shall grant the Lease to the Tenant free from encumbrances other than: 

 

	 	(a)	 any matters, other than financial charges, contained or referred to in the entries or records made in registers
maintained by HM Land Registry as at 25 April 2019 at 11:42:29 under title number 189688; 

  

	 	(b)	 all matters contained or referred to in the Lease; 

 

	 	(c)	 any matters discoverable by inspection of the Property before the date of this agreement;

  

	 	(d)	 any matters which the Landlord does not and could not reasonably know about; 

 

	 	(e)	 any matters, other than financial charges, disclosed or which would have been disclosed by the searches and
enquiries that a prudent tenant would have made before entering into this agreement; 

  

	 	(f)	 public requirements; 

 

	 	(g)	 any matters which are, or (where the Lease will not be registered) would be, unregistered interests which
override first registration under Schedule 1 to the Land Registration Act 2002, provided that the Landlord warrants that it has disclosed all such matters of which it is aware. 

  
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	18.2	 The Tenant is deemed to have full knowledge of the matters referred to in clause 18.1 and shall not raise any
enquiry, objection, requisition or claim in respect of any of them. 

  

	18.3	 Conditions 4.1.1, 4.1.2, 4.1.3 and 4.2.1 do not apply to this agreement. 

 

	18.4	 Condition 7.6.3 is amended so that reference to Condition 4.1.2 is reference to clause 18.1.

  

	19.	 Termination on Tenant’s insolvency 

 

	19.1	 An Event of Default is any of the following: 

 

	 	(a)	 the taking of any step in connection with any voluntary arrangement or any other compromise or arrangement for
the benefit of any creditors of the Tenant; 

  

	 	(b)	 the making of an application for an administration order or the making of an administration order in relation
to the Tenant; 

  

	 	(c)	 the giving of any notice of intention to appoint an administrator, or the filing at court of the prescribed
documents in connection with the appointment of an administrator, or the appointment of an administrator, in any case in relation to the Tenant; 

  

	 	(d)	 the appointment of a receiver or manager or an administrative receiver in relation to any property or income of
the Tenant; 

  

	 	(e)	 the commencement of a voluntary winding-up in respect of the Tenant,
except a winding-up for the purpose of amalgamation or reconstruction of a solvent company in respect of which a statutory declaration of solvency has been filed with the Registrar of Companies;

  

	 	(f)	 the making of a petition for a winding-up order or a winding-up order in respect of the Tenant; 

  

	 	(g)	 the striking-off of the Tenant from the Register of Companies or the
making of an application for the Tenant to be struck-off; 

  

	 	(h)	 the Tenant otherwise ceasing to exist. 

 

	19.2	 If an Event of Default occurs, the Landlord may, at any time prior to grant of the Lease, terminate this
agreement by giving written notice to the Tenant. 

  

	20.	 Consequences of termination 

 

	20.1	 If this agreement is terminated in accordance with clause 8 or clause 19.2 or Condition 10.1(b), 10.5.1 or
10.6.1: 

  
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	 	(a)	 this agreement shall be terminated with immediate effect from the date of the notice to terminate and none of
the parties shall have any further rights or obligations under this agreement except for: 

  

	 	(i)	 the rights of any party in respect of any earlier breach of this agreement; 

 

	 	(ii)	 the obligations in clause 20 and clause 22.3 which shall continue in force notwithstanding the termination or
rescission of this agreement; and 

  

	 	(b)	 the Tenant shall return any documents it received from the Landlord. 

 

	20.2	 Condition 10.2 is varied to read: “if either party rescinds the contract, clause 20.1 shall apply.”

  

	20.3	 Condition 10.5.1 is varied to read: “If the buyer fails to complete in accordance with a notice to
complete, the seller may rescind the contract, and if it does so clause 20.1 shall apply.” 

  

	20.4	 Condition 10.6.1 is varied to read: “If the seller fails to complete in accordance with a notice to
complete, the buyer may rescind the contract, and if it does so clause 20.1 shall apply.” 

  

	20.5	 Conditions 10.5.2, 10.5.3, 10.6.2 and 10.6.3 do not apply to this agreement. 

 

	21.	 Completion of grant of the lease 

 

	21.1	 Completion of the grant of the Lease the Licence for Alterations and the Rent Deposit Deed shall take place on
the Lease Completion Date. 

  

	21.2	 On completion, the Tenant shall pay to the Landlord: 

 

	 	(a)	 the Insurance Rent payable under the Lease for the period from and including the Lease Completion Date up to
the policy renewal date; and 

  

	 	(b)	 the rent deposit funds under the Rent Deposit Deed being a sum equal to six months of Rent plus an amount equal
to VAT thereon (ignoring any rent free period allowed to the Tenant). 

  

	21.3	 If completion is delayed due to the Tenant’s default or the Tenant fails to pay any sum due under this
agreement in full on completion, the Tenant shall pay interest in addition to damages for losses incurred by the Landlord as a result of the delayed completion. The interest shall be payable at the Contract Rate on any unpaid amount for the period
from the Lease Completion Date to the date of actual payment. 

  

	21.4	 Condition 9.7 is amended to read: “The Tenant is to pay the money due on completion by Electronic
Payment”. 

  
 17 

	21.5	 Condition 10.3 does not apply to this agreement. 

 

	21.6	 Within two months after the Lease Completion Date the Landlord shall provide to the Tenant a set of as built
drawings relating to the Landlord’s Works Operating and Maintenance Manuals and if applicable a copy of the Health and Safety file. 

  

	22.	 Registration 

  

	22.1	 The Tenant may note this agreement by way of a unilateral notice against the Landlord’s title.

  

	22.2	 The Tenant is not permitted to: 

 

	 	(a)	 note this agreement against the Landlord’s title by way of an agreed notice; or 

 

	 	(b)	 send this agreement or a copy of it to HM Land Registry. 

 

	22.3	 On the earlier of the completion of the Lease or termination of this agreement, the Tenant shall:

  

	 	(a)	 immediately cancel all entries relating to this agreement registered against the Landlord’s title; and

  

	 	(b)	 promptly notify the Landlord when such application has been completed. 

 

	23.	 VAT 

  

	23.1	 Each amount stated to be payable by the Tenant to the Landlord under or pursuant to this agreement is exclusive
of VAT (if any). 

  

	23.2	 If any VAT is chargeable on any supply made by the Landlord to the Tenant under or pursuant to this agreement,
the paying party shall pay to the other party an amount equal to that VAT. 

  

	23.3	 Condition 2 does not apply to this agreement. 

 

	24.	 Entire agreement 

 

	24.1	 This agreement and the documents annexed to it constitute the whole agreement between the parties and supersede
all previous discussions, correspondence, negotiations, arrangements, understandings and agreements between them relating to their subject matter. 

  

	24.2	 The Tenant acknowledges that in entering into this agreement and any documents annexed to it the Tenant does
not rely on, and shall have no remedies in respect of, any representation or warranty (whether made innocently or negligently) other than those: 

  
 18 

	 	(a)	 set out in this agreement or the documents annexed to it; or 

 

	 	(b)	 contained in any Written Replies. 

 

	24.3	 Nothing in this clause shall limit or exclude any liability for fraud. 

 

	24.4	 Condition 10.1 is varied so that the words “the negotiations leading to it” are replaced with the
words “Written Replies”. 

  

	25.	 Joint and several liability 

 

	25.1	 Where the Landlord comprises more than one person, those persons shall be jointly and severally liable for the
obligations and liabilities of the Landlord arising under this agreement. The Tenant may take action against, or release or compromise the liability of, or grant time or other indulgence to, any one of those persons without affecting the liability
of any other of them. 

  

	25.2	 Where the Tenant comprises more than one person, those persons shall be jointly and severally liable for the
obligations and liabilities of the Tenant arising under this agreement. The Landlord may take action against, or release or compromise the liability of, or grant time or other indulgence to, any one of those persons without affecting the liability
of any other of them. 

  

	25.3	 Condition 1.2 does not apply to this agreement. 

 

	26.	 Notices 

  

	26.1	 Any notice given under this agreement must be in writing and signed by or on behalf of the party giving it.

  

	26.2	 Any notice or document to be given or delivered under this agreement must be: (a) delivered by hand; or
(b) sent by pre-paid first class post or other next working day delivery service; or (c) sent through the document exchange (DX). 

 

	26.3	 Any notice or document to be given or delivered under this agreement must be sent to the relevant party as
follows: 

  

	 	(a)	 to the Landlord at: 

64 New Cavendish Street London W1G 8TB 

marked for the attention of: Ronald Harris 

or at the Landlord’s Conveyancer, quoting the reference 145/319442/3; 

  
 19 

	 	(b)	 to the Tenant at its registered office. 

or as otherwise specified by the relevant party by notice in writing to each other party. 

 

	26.4	 Any change of the details in clause 26.3 specified in accordance with that clause shall take effect for the
party notified of the change at 9.00 am on the later of: 

  

	 	(a)	 the date, if any, specified in the notice as the effective date for the change; or 

 

	 	(b)	 the date five working days after deemed receipt of the notice. 

 

	26.5	 Giving or delivering a notice or a document to a party’s conveyancer has the same effect as giving or
delivering it to that party. 

  

	26.6	 Any notice or document given or delivered in accordance with clause 26.1, clause 26.2 and clause 26.3 will be
deemed to have been received: 

  

	 	(a)	 if delivered by hand, on signature of a delivery receipt or at the time the notice or document is left at the
address provided that if delivery occurs before 9.00 am on a working day, the notice will be deemed to have been received at 9.00 am on that day, and if delivery occurs after 5.00 pm on a working day, or on a day which is not a working day, the
notice will be deemed to have been received at 9.00 am on the next working day; or 

  

	 	(b)	 if sent by pre-paid first class post or other next working day delivery
service, at 9.00 am on the next working day after posting; or 

  

	 	(c)	 if sent through the DX, at 9.00 am on the next working day after being put into the DX. 

 

	26.7	 In proving delivery of a notice or document, it will be sufficient to prove that: 

 

	 	(a)	 a delivery receipt was signed or that the notice or document was left at the address; or 

 

	 	(b)	 the envelope containing the notice or document was properly addressed and posted by pre-paid first class post or other next working day delivery service; or 

  

	 	(c)	 the envelope containing the notice or document was properly addressed and was put in the DX.

  

	26.8	 A notice or document given or delivered under this agreement shall not be validly given or delivered if sent by
email or fax. 

  

	26.9	 Condition 1.3 does not apply to this agreement. 

 

	26.10	 This clause does not apply to the service of any proceedings or other documents in any legal action or, where
applicable, any arbitration or other method of dispute resolution. 

  
 20 

	27.	 Third party rights 

 

	27.1	 A person who is not a party to this agreement shall not have any rights under the Contracts (Rights of Third
Parties) Act 1999 to enforce any term of this agreement. 

  

	27.2	 Condition 1.5 is excluded. 

 

	28.	 Governing law 

This agreement and any dispute or claim (including non-contractual disputes or claims) arising out of
or in connection with it or its subject matter or formation shall be governed by and construed in accordance with the law of England and Wales. 
  

	29.	 Jurisdiction 

Each party irrevocably agrees that the courts of England and Wales shall have exclusive jurisdiction to settle any dispute or claim (including non-contractual disputes or claims) arising out of or in connection with this agreement or its subject matter or formation. 

This agreement has been entered into on the date stated at the beginning of it. 

  
 21 

			
	Signed for and on behalf of	  	/s/ Ronald Harris
	PROVOST 1 LIMITED	  	Director
		
	Signed for and on behalf of	  	/s/ Ronald Harris
	PROVOST 2 LIMITED	  	Director
		
	Signed for and on behalf of	  	/s/ Richard Giroux
	MEIRAGTX UK II LIMITED	  	Director

  
 22 

 

 

Dated                    2019 

Lease 
 relating to 

34 – 38 Provost Street London N1 7NG 
 between

  

	(1)	 Provost 1 Limited and Provost 2 Limited 

 

	(2)	 Meiragtx UK II Limited 

 

									
	Harbottle & Lewis LLP	  	T + 44 (0)20 7667 5000	  		  		  	
	Hanover House	  	F + 44 (0)20 7667 5100	  		  		  	
	14 Hanover Square	  	www.harbottle.com	  		  		  	
	London	  	DX 44617 Mayfair	  		  		  	
	W1S 1HP	  		  		  		  	
					
	Ref: 145/319442.3	  		  		  		  	

  

							
	 CONTENTS

 
	  	 	 	 
	 CLAUSE
	  			
			
	 1.
	 	 Interpretation
	  	 	1	 
			
	 2.
	 	 Grant
	  	 	6	 
			
	 3.
	 	 Ancillary rights
	  	 	6	 
			
	 4.
	 	 Rights excepted and reserved
	  	 	6	 
			
	 5.
	 	 Third Party Rights
	  	 	7	 
			
	 6.
	 	 The Annual Rent
	  	 	8	 
			
	 7.
	 	 Review of the Annual Rent
	  	 	8	 
			
	 8.
	 	 Insurance
	  	 	11	 
			
	 9.
	 	 Uninsured Risks
	  	 	13	 
			
	 10.
	 	 Rates and taxes
	  	 	14	 
			
	 11.
	 	 Utilities
	  	 	15	 
			
	 12.
	 	 Common items
	  	 	15	 
			
	 13.
	 	 VAT
	  	 	15	 
			
	 14.
	 	 Default interest and interest
	  	 	15	 
			
	 15.
	 	 Costs
	  	 	16	 
			
	 16.
	 	 Compensation on vacating
	  	 	16	 
			
	 17.
	 	 Set-off
	  	 	16	 
			
	 18.
	 	 Registration of this lease
	  	 	17	 
			
	 19.
	 	 Assignments
	  	 	17	 
			
	 20.
	 	 Underlettings
	  	 	18	 
			
	 21.
	 	 Sharing occupation
	  	 	20	 
			
	 22.
	 	 Charging
	  	 	20	 
			
	 23.
	 	 Prohibition of other dealings
	  	 	20	 
			
	 24.
	 	 Registration and notification of dealings and occupation
	  	 	21	 
			
	 25.
	 	 Closure of the registered title of this lease
	  	 	21	 
			
	 26.
	 	 Repairs
	  	 	22	 

							
			
	27.	 	Decoration	  	22
			
	28.	 	Alterations	  	22
			
	29.	 	Signs and Building Naming	  	23
			
	30.	 	Returning the Property to the Landlord	  	23
			
	31.	 	Use	  	24
			
	32.	 	Compliance with laws	  	24
			
	33.	 	Energy performance certificates	  	25
			
	34.	 	Encroachments, obstructions and acquisition of rights	  	26
			
	35.	 	Breach of repair and maintenance obligations	  	26
			
	36.	 	Indemnity	  	27
			
	37.	 	Landlord’s covenant for quiet enjoyment	  	27
			
	38.	 	Guarantee and indemnity	  	27
			
	39.	 	Re-entry and forfeiture	  	27
			
	40.	 	Joint and several liability	  	28
			
	41.	 	Entire agreement	  	28
			
	42.	 	Notices, consents and approvals	  	29
			
	43.	 	Governing law	  	30
			
	44.	 	Jurisdiction	  	30
			
	45.	 	Exclusion of sections 24-28 of the LTA 1954	  	30
			
	46.	 	Contracts (Rights of Third Parties) Act 1999	  	30
			
	47.	 	Tenant’s Break Option	  	31

  

							
		
	SCHEDULE	  	
			
	Schedule 1	 	Guarantee and indemnity	  	32

									
			
	1.	 	Guarantee and indemnity	  	 	32	 
			
	2.	 	Guarantor’s liability	  	 	32	 
			
	3.	 	Variations and supplemental documents	  	 	33	 
			
	4.	 	Guarantor to take a new lease or make payment	  	 	34	 
			
	5.	 	Rent at the date of forfeiture or disclaimer	  	 	35	 
			
	6.	 	 Payments in gross and restrictions on the Guarantor
	  	 	35	 
			
	7.	 	 Other securities
	  	 	35	 

	LR1.	 Date of lease 

2019 
  

	LR2.	 Title number(s) 

LR2.1 Landlord’s title number(s) 

189688 
 LR2.2 Other title
numbers 
 None 
  

	LR3.	 Parties to this lease 

Landlord 
 Provost 1
Limited (Company Registration Number: 11228901) and Provost 2 Limited (Company Registration Number: 11228852) both of whose registered office is at 64 New Cavendish Street London W1G 8TB 

Tenant 
 Meiragtx UK II
Limited (Company Registration Number: 09348737) whose registered office is at 92 Britannia Walk London N1 7NQ 
 Other parties 

None 
 Guarantor 

None 
  

	LR4.	 Property 

In the case of a conflict between this clause and the remainder of this lease then, for the purposes of registration, this clause shall prevail. 

See the definition of “Property” in clause 1.1 of this lease. 

LR5. Prescribed statements etc. 
 LR5.1
Statements prescribed under rules 179 (dispositions in favour of a charity), 180 (dispositions by a charity) or 196 (leases under the Leasehold Reform, Housing and Urban Development Act 1993) of the Land Registration Rules 2003. 

None. 
 LR5.2 This lease is
made under, or by reference to, provisions of: 
 None. 
  

	LR6.	 Term for which the Property is leased 

The term as specified in this lease at clause 1.1 in the definition of “Contractual Term”. 

 

	LR7.	 Premium 

None. 
  

	LR8.	 Prohibitions or restrictions on disposing of this lease 

This lease contains a provision that prohibits or restricts dispositions. 

	LR9.	 Rights of acquisition etc. 

LR9.1 Tenant’s contractual rights to renew this lease, to acquire the reversion or another lease of the Property, or to acquire an
interest in other land 
 None. 

LR9.2 Tenant’s covenant to (or offer to) surrender this lease 

None. 
 LR9.3 Landlord’s
contractual rights to acquire this lease 
 None. 
  

	LR10.	 Restrictive covenants given in this lease by the Landlord in respect of land other than the Property

 None. 
  

	LR11.	 Easements 

LR11.1 Easements granted by this lease for the benefit of the Property 

None. 
 LR11.2 Easements
granted or reserved by this lease over the Property for the benefit of other property 
 The easements as specified in clause 4 of this
lease. 
  

	LR12.	 Estate rentcharge burdening the Property 

None. 
  

	LR13.	 Application for standard form of restriction 

The Parties to this lease apply to enter the following standard form of restriction [against the title of the Property] [against title number ] 

None. 
  

	LR14.	 Declaration of trust where there is more than one person comprising the Tenant 

					
	 This lease is dated
	  	2019	  	
			
	Parties	  		  	

  

	(1)	 PROVOST 1 LIMITED incorporated and registered in England and Wales with company number 11228901 and
PROVOST 2 LIMITED incorporated and registered in England and Wales with company number 11228852 both of whose registered office is at 64 New Cavendish Street London W1G 8TB and any successor in title (Landlord). 

 

	(2)	 MEIRAGTX UK II LIMITED incorporated and registered in England and Wales with company number 09348737
whose registered office is at 92 Britannia Walk London N1 7NQ (Tenant). 

 Agreed terms 

 

	1.	 Interpretation 

The following definitions and rules of interpretation apply in this lease. 

 

	1.1	 Definitions: 

Act of Insolvency:  

a) the taking of any step in connection with any voluntary arrangement or any other compromise or arrangement for the benefit of any creditors
of the Tenant or any guarantor; 
 b) the making of an application for an administration order or the making of an administration order in
relation to the Tenant or any guarantor; 
 c) the giving of any notice of intention to appoint an administrator, or the filing at court of
the prescribed documents in connection with the appointment of an administrator, or the appointment of an administrator, in any case in relation to the Tenant or any guarantor; 

d) the appointment of a receiver or manager or an administrative receiver in relation to any property or income of the Tenant or any
guarantor; 
 e) the commencement of a voluntary winding-up in respect of the Tenant or any
guarantor, except a winding-up for the purpose of amalgamation or reconstruction of a solvent company in respect of which a statutory declaration of solvency has been filed with the Registrar of Companies;

 f) a winding-up order in respect of the Tenant or any guarantor; g) the striking-off of the Tenant or any guarantor from the Register of Companies; 
 h) the Tenant or any
guarantor otherwise ceasing to exist (but excluding where the Tenant or any guarantor dies); 

 i) the making of an application for a bankruptcy order, the presentation of a petition for
a bankruptcy order or the making of a bankruptcy order against the Tenant or any guarantor; or 
 j) the levying of any execution or other
such process on or against, or taking control or possession of, the whole or any part of the Tenant’s assets. 
 The paragraphs above
shall apply in relation to a partnership or limited partnership (as defined in the Partnership Act 1890 and the Limited Partnerships Act 1907 respectively) subject to the modifications referred to in the Insolvent Partnerships Order 1994 (SI
1994/2421) (as amended), and a limited liability partnership (as defined in the Limited Liability Partnerships Act 2000) subject to the modifications referred to in the Limited Liability Partnerships Regulations 2001 (SI 2001/1090) (as
amended). 
 Act of Insolvency includes any analogous proceedings or events that may be taken pursuant to the legislation of another
jurisdiction in relation to a tenant or guarantor incorporated or domiciled in such relevant jurisdiction. 
 Agreement for Lease: an
Agreement for Lease dated                 2019 relating to the Property and made between (1) the Landlord and (2) the Tenant.  

Annual Rent:  
 a)
from and including the date of commencement of the Contractual Term up to and including the day of                2019 [4 months] one peppercorn (if demanded); 

b) from and including the Rent Commencement Date up to and including
the                2020 [8 months] the rent at the rate of £[    ] per annum exclusive of VAT [half annual rent]; 

c) from and including the                 day
of                 2020 the rent at the rate of £[    ] per annum exclusive of VAT [full annual rent]; and 

d) then the rent as revised pursuant to this Lease. 

Break Date: the                 day
of                 2024.  
 CDM Regulations:
the Construction (Design and Management) Regulations 2015 (SI 2015/51).  
 Contractual Term: a term of ten years beginning on,
and including the date of this lease and ending on, and including                 2029.  

Default Interest Rate: 3% per annum above the Interest Rate.  

Energy Assessor: an individual who is a member of an accreditation scheme approved by the Secretary of State in accordance with
regulation 22 of the Energy Performance of Buildings (England and Wales) Regulations 2012 (SI 2012/3118).  

  
 2 

 Energy Performance Certificate: a certificate as defined in regulation 2(1) of the
Energy Performance of Buildings (England and Wales) Regulations 2012 (SI 2012/3118).  
 Insurance Rent: the aggregate in each
year of the gross cost of the premium before any discount or commission for the insurance of:  
 a) the Property, other than any
plate glass, for its full reinstatement cost (taking inflation of building costs into account) against loss or damage by or in consequence of the Insured Risks, including costs of demolition, site clearance, site protection and shoring-up, professionals’ and statutory fees and incidental expenses, the cost of any work which may be required under any law and VAT in respect of all those costs, fees and expenses; 

b) loss of Annual Rent of the Property for three years; and 

c) any insurance premium tax payable on the above. 

Insured Risks: means fire, explosion, lightning, earthquake, storm, flood, bursting and overflowing of water tanks, apparatus or pipes,
impact by aircraft and articles dropped from them, impact by vehicles, subsidence, ground slip, heave, riot, civil commotion and any other risks against which the Landlord decides to insure against from time to time and Insured Risk means any
one of the Insured Risks.  
 Interest Rate: the base rate from time to time of Barclays Bank, or if that base rate stops being
used or published then a comparable commercial rate reasonably determined by the Landlord.  
 Lifts: all lifts and lift
machinery and equipment within and forming part of the Property.  
 LTA 1954: Landlord and Tenant Act 1954. 

Permitted Part: each whole floor of the Property which is capable of separate occupation and use.  

Permitted Use: offices within Use Class B1 of the Town and Country Planning (Use Classes) Order 1987 as at the date this lease is
granted.  
 Property: the land and building at 34 – 38 Provost Street London N1 7NG being the whole of the land and
buildings comprised in the Landlord’s freehold Title under Title Number 189688.  
 Recommendation Report: a report as
defined in regulation 4 of the Energy Performance of Buildings (England and Wales) Regulations 2012 (SI 2012/3118).  
 Rent
Commencement Date: the                 day of                 2019 [4 months rent
free]. 
 Rent Payment Dates: 25 March, 24 June, 29 September and 25 December.  

Reservations: all of the rights excepted, reserved and granted to the Landlord by this lease.  

  
 3 

 Review Date:
the                 day of                 2024.  

Service Media: all media for the supply or removal of heat, electricity, gas, water, sewage, air conditioning, energy,
telecommunications, data and all other services and utilities and all structures, machinery and equipment ancillary to those media.  

Third Party Rights: all rights, covenants and restrictions affecting the Property including the matters referred to at the date of this
lease in the property and charges registers of title number 189688.  
 VAT: value added tax chargeable under the VATA 1994 and
any similar replacement tax and any similar additional tax.  
 VATA 1994: Value Added Tax Act 1994. 

Uninsured Risks: any risk expressly specified in the definition of the Insured Risks which: 

a) is not insured because insurance is not available or is not available in the London Insurance Market at reasonable commercial rates and/or
on reasonable commercial conditions; or 
 b) is not insured or fully insured by reason of some special limitation or exclusion which may be
imposed by the Landlord’s insurer; 
 such that the full cost of reinstatement and rebuilding (save for any excess) is not recoverable
by the Landlord under its insurance policy(ies) provided that a risk shall not be an Uninsured Risk by reason only of: 
 a) normal policy
exclusion provisions in relation to a level of policy excess; or; 
 b) rejection by the insurer of liability or some part of it due to
vitiation by the Tenant or any persons deriving title under the Tenant or their respective agents, employees, licensees or contractors. 
  

	1.2	 A reference to this lease, except a reference to the date of this lease or to the grant of this lease,
is a reference to this deed and any deed, licence, consent, approval or other instrument supplemental to it. 

  

	1.3	 A reference to the Landlord includes a reference to the person entitled to the immediate reversion to
this lease. A reference to the Tenant includes a reference to its successors in title and assigns. A reference to a guarantor is to any guarantor of the tenant covenants of this lease including a guarantor who has entered into an
authorised guarantee agreement. 

  

	1.4	 In relation to any payment, a reference to a fair proportion is to a fair proportion of the total amount
payable, determined conclusively (except as to questions of law) by the Landlord. 

  
 4 

	1.5	 The expressions landlord covenant and tenant covenant each has the meaning given to it by the
Landlord and Tenant (Covenants) Act 1995. 

  

	1.6	 Unless the context otherwise requires, a reference to the Property is to the whole and any part of it.

  

	1.7	 A reference to the term is to the Contractual Term. 

 

	1.8	 A reference to the end of the term is to the end of the term however it ends. 

 

	1.9	 References to the consent of the Landlord are to the consent of the Landlord given in accordance with
clause 41.5 and references to the approval of the Landlord are to the approval of the Landlord given in accordance with clause 41.6. 

  

	1.10	 A working day is any day which is not a Saturday, a Sunday, a bank holiday or a public holiday in
England. 

  

	1.11	 A reference to laws in general is a reference to all local, national and directly applicable supra-national
laws as amended, extended or re-enacted from time to time and shall include all subordinate laws made from time to time under them and all orders, notices, codes of practice and guidance made under them.

  

	1.12	 Unless otherwise specified, a reference to a statute or statutory provision is a reference to it as amended,
extended or re-enacted from time to time and shall include all subordinate legislation made from time to time under that statute or statutory provision and all orders, notices, codes of practice and guidance
made under it. 

  

	1.13	 Any obligation on the Tenant not to do something includes an obligation not to allow that thing to be done and
an obligation to use best endeavours to prevent that thing being done by another person. 

  

	1.14	 Unless the context otherwise requires, any words following the terms including, include, in
particular, for example or any similar expression shall be construed as illustrative and shall not limit the sense of the words, description, definition, phrase or term preceding those terms. 

 

	1.15	 A person includes a natural person, corporate or unincorporated body (whether or not having separate
legal personality). 

  

	1.16	 A reference to writing or written incudes fax but not email. 

 

	1.17	 Unless the context otherwise requires, references to clauses and Schedules are to the clauses and Schedules of
this lease and references to paragraphs are to paragraphs of the relevant Schedule. 

  
 5 

	1.18	 Clause, Schedule and paragraph headings shall not affect the interpretation of this lease.

  

	1.19	 Unless the context otherwise requires, a reference to one gender shall include a reference to the other
genders. 

  

	1.20	 Unless the context otherwise requires, words in the singular shall include the plural and in the plural shall
include the singular. 

  

	2.	 Grant 

  

	2.1	 The Landlord lets with full title guarantee the Property to the Tenant for the Contractual Term.

  

	2.2	 The grant is made excepting and reserving to the Landlord the rights set out in clause 4, and subject to the
Third Party Rights. 

  

	2.3	 The grant is made with the Tenant paying the following as rent to the Landlord: 

 

	 	(a)	 the Annual Rent and all VAT in respect of it, 

 

	 	(b)	 the Insurance Rent; 

  

	 	(c)	 all interest payable under this lease; and 

 

	 	(d)	 all other sums due under this lease. 

 

	3.	 Ancillary rights 

Neither the grant of this lease nor anything in it confers any right over neighbouring property nor is to be taken to show that the Tenant may
have any right over neighbouring property, and section 62 of the Law of Property Act 1925 does not apply to this lease. 
  

	4.	 Rights excepted and reserved 

 

	4.1	 The following rights are excepted and reserved from this lease to the Landlord to the extent possible for the
benefit of any neighbouring or adjoining property in which the Landlord acquires an interest during the term: 

  

	 	(a)	 rights of light, air, support and protection to the extent those rights are capable of being enjoyed at any
time during the term; 

  

	 	(b)	 the right to use and to connect into Service Media at the Property which are in existence at the date of this
lease or which are installed or constructed during the Contractual Term; 

  
 6 

	 	(c)	 at any time during the term, the full and free right to develop any neighbouring or adjoining property in which
the Landlord acquires an interest during the term as the Landlord may think fit; and 

 the right to build on or into any
boundary wall of the Property in connection with any of the Reservations; notwithstanding that the exercise of any of the Reservations or the works carried out pursuant to them result in a reduction in the flow of light or air to the Property or
loss of amenity for the Property provided that they do not materially affect the use and enjoyment of the Property for the Permitted Use. 
  

	4.2	 The Landlord reserves the right to enter the Property: 

 

	 	(a)	 to repair, maintain or replace any Service Media or structure relating to any of the Reservations; and

  

	 	(b)	 for any other purpose mentioned in or connected with: 

 

	 	(i)	 this lease; 

  

	 	(ii)	 the Reservations; and 

 

	 	(iii)	 the Landlord’s interest in the Property. 

 

	4.3	 The Reservations may be exercised by the Landlord and by anyone else who is or becomes entitled to exercise
them, and by anyone authorised by the Landlord. 

  

	4.4	 The Tenant shall allow all those entitled to exercise any right to enter the Property, to do so with their
workers, contractors, agents and professional advisors, and to enter the Property at any reasonable time (whether or not during usual business hours) and, except in the case of an emergency, after having given reasonable notice (which need not be in
writing) to the Tenant. 

  

	4.5	 No party exercising any of the Reservations, nor its workers, contractors, agents and professional advisors,
shall be liable to the Tenant or to any undertenant or other occupier of or person at the Property for any loss, damage, injury, nuisance or inconvenience arising by reason of its exercising any of those Reservations except for:

  

	 	(a)	 physical damage to the Property; or 

 

	 	(b)	 any loss, damage, injury, nuisance or inconvenience in relation to which the law prevents the Landlord from
excluding liability. 

  

	5.	 Third Party Rights 

 

	5.1	 The Tenant shall comply with all obligations on the Landlord relating to the Third Party Rights (insofar as
those obligations relate to the Property) and shall not do anything (even if otherwise permitted by this lease) that may interfere with any Third Party Right. 

  
 7 

	5.2	 The Tenant shall allow the Landlord and any other person authorised by the terms of the Third Party Right to
enter the Property in accordance with its terms. 

  

	6.	 The Annual Rent 

 

	6.1	 The Tenant shall pay the Annual Rent and any VAT in respect of it by four equal instalments in advance on or
before the Rent Payment Dates. The payments shall be made by banker’s standing order or by any other method that the Landlord requires at any time by giving notice to the Tenant. 

 

	6.2	 The first instalment of the Annual Rent and any VAT in respect of it shall be made on the Rent Commencement
Date and shall be the proportion, calculated on a daily basis, in respect of the period beginning on the Rent Commencement Date and ending on the day before the next Rent Payment Date. 

 

	7.	 Review of the Annual Rent 

 

	7.1	 In this clause the President is the President for the time being of the Royal Institution of Chartered
Surveyors or a person acting on his behalf, and the Surveyor is the independent valuer appointed pursuant to clause 7.7. 

  

	7.2	 The amount of Annual Rent shall be reviewed on each Review Date to equal: 

 

	 	(a)	 the Annual Rent payable immediately before the relevant Review Date (or which would then be payable but for any
abatement or suspension of the Annual Rent or restriction on the right to collect it) or, if greater; 

  

	 	(b)	 the open market rent agreed or determined pursuant to this clause. 

 

	7.3	 The open market rent may be agreed between the Landlord and the Tenant at any time before it is determined by
the Surveyor. 

  

	7.4	 If the open market rent is determined by the Surveyor, it shall be the amount that the Surveyor determines is
the annual rent (exclusive of any VAT) at which the Property could reasonably be expected to be let: 

  

	 	(a)	 in the open market; 

  

	 	(b)	 at the relevant Review Date; 

 

	 	(c)	 on the assumptions listed in clause 7.5; and 

 

	 	(d)	 disregarding the matters listed in clause 7.6. 

 

	7.5	 The assumptions are: 

 

	 	(a)	 the Property is available to let in the open market: 

  
 8 

	 	(i)	 by a willing lessor to a willing lessee; 

 

	 	(ii)	 as a whole; 

  

	 	(iii)	 with vacant possession; 

 

	 	(iv)	 without a fine or a premium; 

 

	 	(v)	 for a term equal to the unexpired residue of the Contractual Term at the Review Date; and

  

	 	(vi)	 otherwise on the terms of this lease other than as to the amount of the Annual Rent but including the
provisions for review of the Annual Rent; 

  

	 	(b)	 the willing lessee has had the benefit of any rent-free or other concession or contribution which would be
offered in the open market at the Review Date in relation to fitting out works at the Property; 

  

	 	(c)	 the Property may lawfully be used, and is in a physical state to enable it to be lawfully used, by the willing
lessee (or any potential undertenant or assignee of the willing lessee) for any purpose permitted by this lease; 

  

	 	(d)	 the Landlord and the Tenant have fully complied with their obligations in this lease; 

 

	 	(e)	 if the Property or any means of access to it or any Service Media serving the Property, has been destroyed or
damaged, it has been fully restored; 

  

	 	(f)	 no work has been carried out on the Property that has diminished its rental value other than work carried out
in compliance with clause 31; 

  

	 	(g)	 any fixtures, fittings, machinery or equipment supplied to the Property by the Landlord that have been removed
by or at the request of the Tenant, or any undertenant or their respective predecessors in title (otherwise than to comply with any law) remain at the Property; and 

 

	 	(h)	 the willing lessee and its potential assignees and undertenants shall not be disadvantaged by any actual or
potential exercise of an option to tax under Part 1 of Schedule 10 to the VATA 1994 in relation to the Property. 

  

	7.6	 The matters to be disregarded are: 

 

	 	(a)	 any effect on rent of the fact that the Tenant or any authorised undertenant has been in occupation of the
Property; 

  

	 	(b)	 any goodwill attached to the Property by reason of any business carried out there by the Tenant or by any
authorised undertenant or by any of their predecessors in business; 

  

	 	(c)	 any effect on rent attributable to any physical improvement to the Property carried out after the date of this
lease, by or at the expense of the Tenant or any authorised undertenant with all necessary consents, approvals and authorisations and not pursuant to an obligation to the Landlord (other than an obligation to comply with any law);

  
 9 

	 	(d)	 any effect on rent of any obligation on the Tenant to reinstate the Property to the condition or design it was
in before any alterations or improvements were carried out; and 

  

	 	(e)	 any statutory restriction on rents or the right to recover them. 

 

	7.7	 The Surveyor shall be an independent valuer who is a Member or Fellow of the Royal Institution of Chartered
Surveyors. The Landlord and the Tenant may, by agreement, appoint the Surveyor at any time before either of them applies to the President for the Surveyor to be appointed. Any application to the President may not be made earlier than three months
before the Review Date. 

  

	7.8	 The Surveyor shall act as an expert and not as an arbitrator. The Surveyor shall determine the open market rent
and shall have power to determine any issue involving the interpretation of any provision of this lease, his jurisdiction to determine the matters and issues referred to him or his terms of reference. The Surveyor’s decision shall be given in
writing, and the Surveyor shall provide reasons for any determination. The Surveyor’s written decision on the matters referred to him shall be final and binding in the absence of manifest error or fraud. 

 

	7.9	 The Surveyor shall give the Landlord and the Tenant an opportunity to make written representations to the
Surveyor and to make written counter-representations commenting on the representations of the other party to the Surveyor. The parties will provide (or procure that others provide) the Surveyor with such assistance and documents as the Surveyor
reasonably requires for the purpose of reaching a decision. 

  

	7.10	 If the Surveyor dies, or becomes unwilling or incapable of acting, or unreasonably delays in making any
determination, then either the Landlord or the Tenant may apply to the President to discharge the Surveyor and clause 7.7 shall then apply in relation to the appointment of a replacement. 

 

	7.11	 The fees and expenses of the Surveyor and the cost of the Surveyor’s appointment and any counsel’s
fees, or other fees, incurred by the Surveyor shall be payable by the Landlord and the Tenant in the proportions that the Surveyor directs (or if the Surveyor makes no direction, then equally). If the Tenant does not pay its part of the
Surveyor’s fees and expenses within ten working days after demand by the Surveyor, the Landlord may pay that part and the amount it pays shall be a debt of the Tenant due and payable on demand to the Landlord. The Landlord and the Tenant shall
otherwise each bear their own costs in connection with the rent review. 

  
 10 

	7.12	 If the revised Annual Rent has not been agreed by the Landlord and the Tenant or determined by the Surveyor on
or before the Review Date, the Annual Rent payable from (and including) the Review Date shall continue at the rate payable immediately before the Review Date. No later than five working days after the revised Annual Rent is agreed or the
Surveyor’s determination is notified to the Landlord and the Tenant, the Tenant shall pay: 

  

	 	(a)	 the shortfall (if any) between the amount that it has paid for the period from and including the Review Date
until the Rent Payment Date following the date of agreement or notification of the revised Annual Rent and the amount that would have been payable had the revised Annual Rent been agreed or determined on or before the Review Date; and

  

	 	(b)	 interest at the Interest Rate on that shortfall calculated on a daily basis by reference to the Rent Payment
Dates on which parts of the shortfall would have been payable if the revised Annual Rent had been agreed or determined on or before the Review Date and the date payment is received by the Landlord. 

 

	7.13	 Time shall not be of the essence for the purposes of this clause. 

 

	7.14	 If at any time there is a guarantor, the guarantor shall not have any right to participate in the review of the
Annual Rent. 

  

	7.15	 As soon as practicable after the amount of the revised Annual Rent has been agreed or determined, a memorandum
recording the amount shall be signed by or on behalf of the Landlord and the Tenant and endorsed on or attached to this lease and its counterpart. The Landlord and the Tenant shall each bear their own costs in connection with the memorandum.

  

	8.	 Insurance 

  

	8.1	 Subject to clause 8.2, the Landlord shall keep the Property (other than any plate glass at the Property)
insured against loss or damage by the Insured Risks for the sum which the Landlord considers to be its full reinstatement cost (taking inflation of building costs into account). The Landlord shall not be obliged to insure any part of the Property
installed by the Tenant. 

  

	8.2	 The Landlord’s obligation to insure is subject to: 

 

	 	(a)	 any exclusions, limitations, excesses and conditions that may be imposed by the insurers; and

  

	 	(b)	 insurance being available in the London insurance market on reasonable terms acceptable to the Landlord.

  

	8.3	 The Tenant shall pay to the Landlord on demand: 

  
 11 

	 	(a)	 the Insurance Rent; 

  

	 	(b)	 any amount that is deducted or disallowed by the insurers pursuant to any excess provision in the insurance
policy; and 

  

	 	(c)	 any costs that the Landlord incurs in obtaining a valuation of the Property for insurance purposes.

 If the Landlord insures the Property together with other land, the amount of the Insurance Rent shall be a fair
proportion of the total for the Property and the other land. 
  

	8.4	 The Tenant shall: 

  

	 	(a)	 as soon as it becomes aware inform the Landlord if any matter occurs that any insurer or underwriter may treat
as material in deciding whether or on what terms to insure or to continue to insure the Property and shall give the Landlord notice of that matter; 

  

	 	(b)	 not do or omit anything as a result of which any policy of insurance of the Property or any neighbouring
property may become void or voidable or otherwise prejudiced, or the payment of any policy money may be withheld, nor (unless the Tenant has previously notified the Landlord and has paid any increased or additional premium) anything as a result of
which any increased or additional insurance premium may become payable; 

  

	 	(c)	 comply at all times with the requirements and recommendations of the insurers relating to the Property;

  

	 	(d)	 give the Landlord immediate notice of the occurrence of any damage or loss relating to the Property arising
from an Insured Risk or of any other event that might affect any insurance policy relating to the Property; 

  

	 	(e)	 not effect any insurance of the Property (except any plate glass at the Property), but if it becomes entitled
to the benefit of any insurance proceeds in respect of the Property (other than in respect of plate glass) pay those proceeds or cause them to be paid to the Landlord; and 

 

	 	(f)	 pay the Landlord an amount equal to any insurance money that the insurers of the Property refuse to pay by
reason of any act or omission of the Tenant or any undertenant, their workers, contractors or agents or any person at the Property with the actual or implied authority of any of them. 

 

	8.5	 The Landlord shall, subject to obtaining all necessary planning and other consents, use all insurance money
received (other than for loss of rent) to repair the damage for which the money has been received or (as the case may be) in rebuilding the Property. The Landlord shall not be obliged to: 

  
 12 

	 	(a)	 provide accommodation identical in layout or design so long as accommodation reasonably equivalent to that
previously at the Property is provided; or 

  

	 	(b)	 repair or rebuild the Property after a notice has been served pursuant to clause 8.7 or clause 8.8.

  

	8.6	 If the Property is damaged or destroyed by an Insured Risk so as to be unfit for occupation and use then,
unless the policy of insurance of the Property has been vitiated in whole or in part in consequence of any act or omission of the Tenant, any undertenant or their respective workers, contractors or agents or any other person on the Property with the
actual or implied authority of any of them, payment of the Annual Rent, or a fair proportion of it according to the nature and extent of the damage, shall be suspended until the Property has been reinstated and made fit for occupation and use, or
until the end of three years from the date of damage or destruction, if sooner. 

  

	8.7	 If, following damage to or destruction of the Property, the Landlord considers that it is impossible or
impractical to reinstate the Property, the Landlord may terminate this lease by giving notice to the Tenant. On giving notice this lease shall determine but this shall be without prejudice to any right or remedy of the Landlord in respect of any
breach of the tenant covenants of this lease. Any proceeds of the insurance (other than any insurance for plate glass) shall belong to the Landlord. 

  

	8.8	 If, following damage or destruction by an Insured Risk, the Property has not been reinstated so as to be fit
for occupation and use within three years after the date of damage or destruction either the Landlord or the Tenant (provided that in the case of the Tenant the Tenant has complied with its obligations in this clause) may at any time thereafter
terminate this lease by giving notice to the other. On giving this notice this lease shall determine but this shall be without prejudice to any right or remedy of the Landlord in respect of any breach of the tenant covenants of this lease. Any
proceeds of the insurance (other than any insurance for plate glass) shall belong to the Landlord. 

  

	9.	 Uninsured Risks 

 

	9.1	 The following provisions shall apply if the Property or part of it, shall be damaged or destroyed by an
Uninsured Risk so as to make the Property or part of it unfit for occupation and use. 

  

	9.2	 Within 12 months of any damage or destruction by an Uninsured Risk the Landlord will give written notice to the
Tenant (Election Notice) stating whether or not it proposes to reinstate the damage or destruction so as to make the Property again fit for occupation and use. 

  
 13 

	9.3	 If the Election Notice states that the Landlord proposes to reinstate the damage or destruction then for the
purposes of this lease the damage or destruction shall be deemed to have been damage or destruction by an Insured Risk, and the provisions of Clause 8 will apply as if such damage or destruction had been caused by an Insured Risk and the Tenant
shall allow the Landlord all necessary access to the Property to carry out and complete such reinstatement. 

  

	9.4	 If the Election Notice states that the Landlord does not propose to reinstate the damage or destruction or if
no Election Notice is served strictly within the period of 12 months referred to in Clause 9.2 then the Term will automatically determine with immediate effect on the date of the Election Notice or the expiry of the 12 month period (as appropriate).
Any such determination of this lease under this clause will be without prejudice to any claim by either party in respect of any antecedent breach by the other of their obligations under this lease. 

 

	9.5	 The Annual Rent or a fair proportion according to the nature and extent of the damage sustained will not be
payable from the date of such damage or destruction until the Property has been reinstated and made fit for occupation and use or the earlier determination of this lease pursuant to Clause 9.4. 

 

	9.6	 The Landlord shall not be responsible for reinstating any damage or destruction to the Tenant’s fixtures,
fittings and/or contents. 

  

	10.	 Rates and taxes 

 

	10.1	 The Tenant shall pay all present and future rates, taxes and other impositions and outgoings payable in respect
of the Property, its use and any works carried out there, except: 

  

	 	(a)	 any taxes payable by the Landlord in connection with any dealing with or disposition of the reversion to this
lease; or 

  

	 	(b)	 any taxes (other than VAT and insurance premium tax) payable by the Landlord by reason of the receipt of any of
the rents due under this lease. 

  

	10.2	 If any rates taxes or other impositions and outgoings are payable in respect of the Property together with
other property, the Tenant shall pay a fair proportion of the amount payable. 

  

	10.3	 The Tenant shall not make any proposal to alter the rateable value of the Property or that value as it appears
on any draft rating list, without the approval of the Landlord. 

  

	10.4	 If, after the end of the term, the Landlord loses rating relief (or any similar relief or exemption) because it
has been allowed to the Tenant, then the Tenant shall pay the Landlord an amount equal to the relief or exemption that the Landlord has lost. 

  
 14 

	11.	 Utilities 

  

	11.1	 The Tenant shall pay all costs in connection with the supply and removal of electricity, gas, water, sewage,
telecommunications, data and other services and utilities to or from the Property. 

  

	11.2	 If any of those costs are payable in relation to the Property together with other property, the Tenant shall
pay a fair proportion of all those costs. 

  

	11.3	 The Tenant shall comply with all laws and with any recommendations of the relevant suppliers relating to the
use of those services and utilities. 

  

	12.	 Common items 

  

	12.1	 The Tenant shall pay the Landlord on demand a fair and reasonable proportion of all costs payable for the
maintenance, repair, lighting, cleaning and renewal of all Service Media, structures and other items used or capable of being used by the Property in common with other property. 

 

	12.2	 The Tenant shall comply with all reasonable regulations the Landlord may make from time to time in connection
with the use of any of those Service Media, structures or other items. 

  

	13.	 VAT 

  

	13.1	 All sums payable by the Tenant are exclusive of any VAT that may be chargeable. The Tenant shall pay VAT in
respect of all taxable supplies made to it in connection with this lease on the due date for making any payment or, if earlier, the date on which that supply is made for VAT purposes. 

 

	13.2	 Every obligation on the Tenant, under or in connection with this lease, to pay the Landlord or any other person
any sum by way of a refund or indemnity, shall include an obligation to pay an amount equal to any VAT incurred on that sum by the Landlord or other person, except to the extent that the Landlord or other person obtains credit for such VAT under the
Value Added Tax Act 1994. 

  

	14.	 Default interest and interest 

 

	14.1	 If any Annual Rent or any other money payable under this lease has not been paid by the date it is due, whether
it has been formally demanded or not, the Tenant shall pay the Landlord interest on that amount at the Default Interest Rate (both before and after any judgment). Such interest shall accrue on a daily basis for the period beginning on the due date
to and including the date of payment. 

  
 15 

	14.2	 If the Landlord does not demand or accept any Annual Rent or other money due or tendered under this lease
because the Landlord reasonably believes that the Tenant is in breach of any of the tenant covenants of this lease, then the Tenant shall, when that amount is accepted by the Landlord, also pay interest at the Interest Rate on that amount for the
period beginning on the date the amount (or each part of it) became due until the date it is accepted by the Landlord. 

  

	15.	 Costs 

  

	15.1	 The Tenant shall pay the costs and expenses of the Landlord including any solicitors’ or other
professionals’ costs and expenses (incurred both during and after the end of the term) in connection with or in contemplation of any of the following: 

  

	 	(a)	 the enforcement of the tenant covenants of this lease; 

 

	 	(b)	 serving any notice in connection with this lease under section 146 or 147 of the Law of Property Act 1925 or
taking any proceedings under either of those sections, notwithstanding that forfeiture is avoided otherwise than by relief granted by the court; 

  

	 	(c)	 serving any notice in connection with this lease under section 17 of the Landlord and Tenant (Covenants) Act
1995; 

  

	 	(d)	 the preparation and service of a schedule of dilapidations in connection with this lease; or

  

	 	(e)	 any consent or approval applied for under this lease, whether or not it is granted (unless the consent or
approval is unreasonably withheld by the Landlord in circumstances where the Landlord is not unreasonably to withhold it ). 

  

	15.2	 Where the Tenant is obliged to pay or indemnify the Landlord against any solicitors’ or other
professionals’ costs and expenses (whether under this or any other clause of this lease) that obligation extends to those costs and expenses assessed on a full indemnity basis. 

 

	16.	 Compensation on vacating 

Any right of the Tenant or anyone deriving title under the Tenant to claim compensation from the Landlord on leaving the Property under the LTA
1954 is excluded, except to the extent that the legislation prevents that right being excluded. 
  

	17.	 Set-off 

The Annual Rent and all other amounts due under this lease shall be paid by the Tenant or any guarantor (as the case may be) in full without
any set-off, counterclaim, deduction or withholding (other than any deduction or withholding of tax as required by law). 

  
 16 

	18.	 Registration of this lease 

Promptly following the grant of this lease, the Tenant shall apply to register this lease at HM Land Registry. The Tenant shall ensure that any
requisitions raised by HM Land Registry in connection with that application are dealt with promptly and properly. Within one month after completion of the registration, the Tenant shall send the Landlord official copies of its title. 

 

	19.	 Assignments 

  

	19.1	 The Tenant shall not assign the whole of this lease without the consent of the Landlord, such consent not to be
unreasonably withheld or delayed. 

  

	19.2	 The Tenant shall not assign part only of this lease. 

 

	19.3	 The Landlord and the Tenant agree that for the purposes of section 19(1A) of the Landlord and Tenant Act 1927
the Landlord may give its consent to an assignment subject to any or all of the following conditions: 

  

	 	(a)	 a condition that the assignor enters into an authorised guarantee agreement which: 

 

	 	(i)	 is in respect of all the tenant covenants of this lease; 

 

	 	(ii)	 is in respect of the period beginning with the date the assignee becomes bound by those covenants and ending on
the date when the assignee is released from those covenants by virtue of section 5 of the Landlord and Tenant (Covenants) Act 1995; 

  

	 	(iii)	 imposes principal debtor liability on the assignor; 

 

	 	(iv)	 requires (in the event of a disclaimer of this lease) the assignor to enter into a new tenancy for a term equal
to the unexpired residue of the Contractual Term; and 

  

	 	(v)	 is otherwise in a form reasonably required by the Landlord. 

 

	 	(b)	 a condition that if reasonably required by the Landlord: 

 

	 	(i)	 persons of standing acceptable to the Landlord acting reasonably enter into a guarantee and indemnity of the
tenant covenants of this lease in the form set out in the Schedule (but with such amendments and additions as the Landlord may reasonably require); and/or 

  

	 	(ii)	 the assignee shall pay to the Landlord on or before completion of the assignment such sum by way of rent
deposit (being not less than six months’ Annual Rent at the date of completion of the assignment plus an amount equal to VAT thereon) as the Landlord may reasonably require and a rent deposit deed in such form as reasonably required by the
Landlord is entered into. 

  
 17 

	19.4	 The Landlord and the Tenant agree that for the purposes of section 19(1A) of the Landlord and Tenant Act 1927
the Landlord may refuse its consent to an assignment if any of the following circumstances exist at the date of the Tenant’s application for consent to assign the lease: 

 

	 	(a)	 the Annual Rent or any other money due under this lease is outstanding or there is a breach of covenant by the
Tenant that has not been remedied; or 

  

	 	(b)	 in the Landlord’s reasonable opinion the assignee is not of sufficient financial standing to enable it to
comply with the Tenant’s covenants and conditions contained in this lease; 

  

	19.5	 Nothing in this clause shall prevent the Landlord from giving consent subject to any other reasonable
condition, nor from refusing consent to an assignment in any other circumstance where it is reasonable to do so. 

  

	20.	 Underlettings 

 

	20.1	 The Tenant shall not underlet the whole of the Property nor a Permitted Part except in accordance with this
clause nor without the consent of the Landlord, such consent not to be unreasonably withheld or delayed. 

  

	20.2	 The Tenant shall not underlet part only of the Property other than a Permitted Part and then only on the terms
of this clause. 

  

	20.3	 The Tenant shall not underlet the Property or a Permitted Part: 

 

	 	(a)	 together with any property or any right over property that is not included within this lease;

  

	 	(b)	 at a fine or premium or reverse premium; nor 

 

	 	(c)	 allowing any rent free period to the undertenant that exceeds the period as is then usual in the open market in
respect of such a letting. 

  

	20.4	 The Tenant shall not underlet the Property or a Permitted Part unless, before the underlease is granted, the
Tenant has given the Landlord: 

  

	 	(a)	 a certified copy of the notice served on the undertenant, as required by section 38A(3)(a) of the LTA 1954,
applying to the tenancy to be created by the underlease; and 

  
 18 

	 	(b)	 a certified copy of the declaration or statutory declaration made by the undertenant in accordance with the
requirements of section 38A(3)(b) of the LTA 1954. 

  

	20.5	 Any underletting by the Tenant shall be by deed and shall include: 

 

	 	(a)	 an agreement between the Tenant and the undertenant that the provisions of sections 24 to 28 of the LTA 1954
are excluded from applying to the tenancy created by the underlease; 

  

	 	(b)	 the reservation of a rent which is not less than the full open market rental value of the Property (or
Permitted Part) as the case may be at the date the Property (or Permitted Part) as the case may be is underlet and which is payable at the same times as the Annual Rent under this lease (but this shall not prevent an underlease providing for a
rent-free period of a length permitted by clause 19.3(c)); 

  

	 	(c)	 provisions for the review of rent at the same dates and on the same basis as the review of rent in this lease,
unless the term of the underlease does not extend beyond the next Review Date; 

  

	 	(d)	 a covenant by the undertenant, enforceable by and expressed to be enforceable by the Landlord (as superior
landlord at the date of grant) and its successors in title in their own right, to observe and perform the tenant covenants in the underlease and any document that is supplemental or collateral to it and the tenant covenants in this lease (in so far
as they relate to the underlet property), except the covenants to pay the rents reserved by this lease; 

  

	 	(e)	 provisions requiring the consent of the Landlord to be obtained in respect of any matter for which the consent
of the Landlord is required under this lease; and 

  

	 	(f)	 in the case of underletting of a Permitted Part, appropriate tenant covenants requiring the undertenant to pay
an appropriate proportion of: 

  

	 	(i)	 the costs of the insurance of the property demised by the lease; and 

 

	 	(ii)	 the repair, maintenance and decoration of any property which does not form part of the underlet property in a
form first approved by the Landlord (such approval not to unreasonably withheld or delayed); and 

  

	 	(iii)	 rates, taxes and other impositions payable in respect of the property demised by the lease; and

  

	 	(iv)	 all costs in connection with the supply and removal of electricity, gas water, sewage, telecommunications, data
and other services and utilities to or from the property demised by this lease, 

 and shall otherwise be consistent with
and include tenant covenants (in so far as they relate to the underlet property) no less onerous (other than as to the Annual Rent) than those in this lease and in a form approved by the Landlord, such approval not to be unreasonably withheld and
which shall prohibit any further sub-underletting of any sort. 

  
 19 

	20.6	 In relation to any underlease granted by the Tenant, the Tenant shall 

 

	 	(a)	 not vary the terms of the underlease nor accept a surrender of the underlease without the consent of the
Landlord, such consent not to be unreasonably withheld; 

  

	 	(b)	 enforce the tenant covenants in the underlease and not waive any of them nor allow any reduction in the rent
payable under the underlease; and 

  

	 	(c)	 ensure that in relation to any rent review the revised rent is not agreed without the approval of the Landlord,
such approval not to be unreasonably withheld. 

  

	20.7	 In relation to any underlease of a Permitted Part the following conditions must be satisfied:

  

	 	(a)	 no more than two separate occupations (including the occupation of the Tenant itself) shall subsist at any one
time; 

  

	 	(b)	 the Tenant shall remain an occupational tenant of the remainder of the Property at all times; and

  

	 	(c)	 the part intended to be underlet and the remainder of the Property shall in each case be self-contained and
capable of separate use and occupation. 

  

	21.	 Sharing occupation 

The Tenant may share occupation of the Property with any company that is a member of the same group (within the meaning of section 42 of the
LTA 1954) as the Tenant for as long as that company remains within that group and provided that no relationship of landlord and tenant is established by that arrangement. 
  

	22.	 Charging 

  

	22.1	 The Tenant shall not charge the whole of this lease without the consent of the Landlord, such consent not to be
unreasonably withheld. 

  

	22.2	 The Tenant shall not charge part only of this lease. 

 

	23.	 Prohibition of other dealings 

Except as expressly permitted by this lease, the Tenant shall not assign, underlet, charge, part with or share possession or share occupation
of this lease or the Property or hold the lease on trust for any person (except pending registration of a dealing permitted by this lease at HM Land Registry or by reason only of joint legal ownership). 

  
 20 

	24.	 Registration and notification of dealings and occupation 

 

	24.1	 In this clause a Transaction is: 

 

	 	(a)	 any dealing with this lease or the devolution or transmission of, or parting with possession of any interest in
it; or 

  

	 	(b)	 the creation of any underlease or other interest out of this lease, or out of any interest, underlease derived
from it, and any dealing, devolution or transmission of, or parting with possession of any such interest or underlease; or 

  

	 	(c)	 the making of any other arrangement for the occupation of the Property. 

 

	24.2	 In respect of every Transaction that is registrable at HM Land Registry, the Tenant shall promptly following
completion of the Transaction apply to register it (or procure that the relevant person so applies). The Tenant shall (or shall procure that) any requisitions raised by HM Land Registry in connection with an application to register a Transaction are
dealt with promptly and properly. Within one month of completion of the registration, the Tenant shall send the Landlord official copies of its title (and where applicable of the undertenant’s title). 

 

	24.3	 No later than one month after a Transaction the Tenant shall: 

 

	 	(a)	 give the Landlord’s solicitors notice of the Transaction; 

 

	 	(b)	 deliver a certified copy of any document effecting the Transaction to the Landlord’s solicitors;

  

	 	(c)	 pay the Landlord’s solicitors a registration fee of £50 (plus VAT); and 

 

	 	(d)	 deliver to the Landlord’s solicitors a copy of any Energy Performance Certificate and Recommendation
Report issued as a result of the Transaction. 

  

	24.4	 If the Landlord so requests, the Tenant shall promptly supply the Landlord with full details of the occupiers
of the Property and the terms upon which they occupy it. 

  

	25.	 Closure of the registered title of this lease 

Immediately after the end of the term (and notwithstanding that the term has ended), the Tenant shall make an application to close the
registered title of this lease and shall ensure that any requisitions raised by HM Land Registry in connection with that application are dealt with promptly and properly; the Tenant shall keep the Landlord informed of the progress and completion of
its application. 

  
 21 

	26.	 Repairs 

  

	26.1	 The Tenant shall keep the Property clean and tidy and in good and substantial repair and condition and shall
ensure that any Lifts and Service Media within and exclusively serving the Property are kept in good working order. 

  

	26.2	 The Tenant shall not be liable to repair the Property to the extent that any disrepair has been caused by an
Insured Risk or an Uninsured Risk, unless and to the extent that: 

  

	 	(a)	 the policy of insurance of the Property has been vitiated or any insurance proceeds withheld in consequence of
any act or omission of the Tenant, any undertenant or their respective workers, contractors or agents or any person on the Property with the actual or implied authority of any of them[; or 

 

	 	(b)	 the insurance cover in relation to that disrepair is excluded, limited, is unavailable or has not been
extended, as mentioned in clause 8.2. 

  

	27.	 Decoration 

  

	27.1	 The Tenant shall decorate the outside of the Property in every third year of the term and the inside of the
Property in every fifth year of the term and otherwise as often as is reasonably necessary and also in the last three months before the end of the term. 

  

	27.2	 All decoration shall be carried out in a good and proper manner using good quality materials that are
appropriate to the Property and the Permitted Use and shall include all appropriate preparatory work. 

  

	27.3	 All decoration carried out in the last three months of the term shall also be carried out to the satisfaction
of the Landlord and using materials, designs and colours approved by the Landlord. 

  

	27.4	 The Tenant shall replace the floor coverings at the Property within the three months before the end of the term
with new ones of good quality and appropriate to the Property and the Permitted Use. 

  

	28.	 Alterations 

  

	28.1	 The Tenant shall not make any external or structural alteration or addition to the Property and shall not make
any opening in any boundary structure of the Property. 

  

	28.2	 The Tenant shall not install any Service Media on the exterior of the Property nor alter the route of any
Service Media at the Property without the consent of the Landlord, such consent not to be unreasonably withheld. 

  
 22 

	28.3	 The Tenant shall not make any internal, non-structural alteration to
the Property without the consent of the Landlord, such consent not to be unreasonably withheld or delayed other than as mentioned in clause 27.4. 

  

	28.4	 The Tenant may install and remove non-structural, demountable
partitioning, without the consent of the Landlord provided that: 

  

	 	(a)	 the Tenant shall not carry out any such works until it has given the Landlord three copies of the plans and
specification for the works; and 

  

	 	(b)	 such partitioning works do not have a negative impact on the Property or the Service Media and do not have a
negative impact on the aesthetics of the external window lines and are in full compliance with all statutes and local authority requirements; and 

  

	 	(c)	 the Tenant shall make good any damage caused to the Property by such installation and/or removal.

  

	28.5	 The Tenant shall not carry out any alteration to the Property which would, or may reasonably be expected to,
have an adverse effect on the asset rating in any Energy Performance Certificate commissioned in respect of the Property. 

  

	29.	 Signs and Building Naming 

 

	29.1	 In this clause Signs include signs, fascia, placards, boards, posters and advertisements.

  

	29.2	 The Tenant shall not attach any Signs to the exterior of the Property or display any inside the Property except
Signs of a design, size and number and in a position that are appropriate to the Property and the Permitted Use and without the consent of the Landlord, such consent not to be unreasonably withheld or delayed. 

 

	29.3	 Before the end of the term, the Tenant shall remove any Signs placed by it at the Property and shall make good
any damage caused to the Property by that removal. 

  

	29.4	 The Tenant shall allow the Landlord to fix to and keep at the Property any sale or re-letting board as the Landlord reasonably requires. 

  

	29.5	 The Tenant shall be permitted to name the Property with the Landlord’s prior written consent to such name,
such consent not to be unreasonably withheld. 

  

	30.	 Returning the Property to the Landlord 

 

	30.1	 At the end of the term the Tenant shall return the Property to the Landlord in the repair and condition
required by this lease. 

  
 23 

	30.2	 Unless to the extent that the Landlord notifies the Tenant in writing to the contrary, the Tenant shall before
the end of the term remove items it has fixed to the Property, remove any alterations it has made to the Property (or the parts specified by the Landlord), and make good any damage caused to the Property by that removal to the Landlord’s
reasonable satisfaction. 

  

	30.3	 At the end of the term, the Tenant shall remove from the Property all chattels belonging to or used by it.

  

	30.4	 The Tenant irrevocably appoints the Landlord to be the Tenant’s agent to store or dispose of any chattels
or items it has fixed to the Property and which have been left by the Tenant on the Property for more than ten working days after the end of the term. The Landlord shall not be liable to the Tenant by reason of that storage or disposal. The Tenant
shall indemnify the Landlord in respect of any claim made by a third party in relation to that storage or disposal. 

  

	31.	 Use 

  

	31.1	 The Tenant shall not use the Property for any purpose other than the Permitted Use. 

 

	31.2	 The Tenant shall not use the Property for any illegal purpose nor for any purpose or in a manner that would
cause loss, damage, injury, nuisance or inconvenience to the Landlord, its other tenants or any other owner or occupier of neighbouring property. 

  

	31.3	 The Tenant shall not overload any structural part of the Property nor any machinery or equipment at the
Property nor any Service Media at or serving the Property. 

  

	32.	 Compliance with laws 

 

	32.1	 The Tenant shall comply with all laws relating to: 

 

	 	(a)	 the Property and the occupation and use of the Property by the Tenant; 

 

	 	(b)	 the use or operation of all Service Media and machinery and equipment at or serving the Property whether or not
used or operated, and shall, where necessary, replace or convert such Service Media within or exclusively serving the Property so that it is capable of lawful use or operation; 

 

	 	(c)	 any works carried out at the Property; and 

 

	 	(d)	 all materials kept at or disposed from the Property. 

 

	32.2	 Without prejudice to any obligation on the Tenant to obtain any consent or approval under this lease, the
Tenant shall carry out all works that are required under any law to be carried out at the Property whether by the owner or the occupier. 

  
 24 

	32.3	 Within five working days after receipt of any notice or other communication affecting the Property (and whether
or not served pursuant to any law) the Tenant shall: 

  

	 	(a)	 send a copy of the relevant document to the Landlord; and 

 

	 	(b)	 take all steps necessary to comply with the notice or other communication and take any other action in
connection with it as the Landlord may require. 

  

	32.4	 The Tenant shall not apply for any planning permission for the Property without the Landlord’s consent not
to be unreasonably withheld. 

  

	32.5	 The Tenant shall comply with its obligations under the CDM Regulations, including all requirements in relation
to the provision and maintenance of a health and safety file. The Tenant shall maintain the health and safety file for the Property in accordance with the CDM Regulations and shall give it to the Landlord at the end of the term.

  

	32.6	 The Tenant shall supply all information to the Landlord that the Landlord reasonably requires from time to time
to comply with the Landlord’s obligations under the CDM Regulations. 

  

	32.7	 As soon as the Tenant becomes aware of any defect in the Property, it shall give the Landlord notice of it. The
Tenant shall indemnify the Landlord against any liability under the Defective Premises Act 1972 in relation to the Property by reason of any failure of the Tenant to comply with any of the tenant covenants in this lease. 

 

	32.8	 The Tenant shall keep the Property equipped with all fire prevention, detection and fighting machinery and
equipment and fire alarms which are required under all relevant laws or required by the insurers of the Property or reasonably recommended by them or reasonably required by the Landlord and shall keep that machinery, equipment and alarms properly
maintained and available for inspection. 

  

	33.	 Energy performance certificates 

 

	33.1	 The Tenant shall: 

  

	 	(a)	 cooperate with the Landlord so far as is reasonably necessary to allow the Landlord to obtain an Energy
Performance Certificate and Recommendation Report for the Property including providing the Landlord with copies of any plans or other information held by the Tenant that would assist in obtaining an Energy Performance Certificate; and

  

	 	(b)	 allow such access to any Energy Assessor appointed by the Landlord as is reasonably necessary to inspect the
Property for the purposes of preparing an Energy Performance Certificate and/or Recommendation Report for the Property. 

  
 25 

	33.2	 The Tenant shall not commission an Energy Performance Certificate for the Property without the Landlord’s
consent such consent not to be unreasonably withheld. 

  

	34.	 Encroachments, obstructions and acquisition of rights 

 

	34.1	 The Tenant shall not grant any right or licence over the Property to a third party. 

 

	34.2	 If a third party makes or attempts to make any encroachment over the Property or takes any action by which a
right may be acquired over the Property, the Tenant shall: 

  

	 	(a)	 immediately inform the Landlord and shall give the Landlord notice of that encroachment or action; and

  

	 	(b)	 take all steps (including any proceedings) the Landlord reasonably requires to prevent or license the
continuation of that encroachment or action. 

  

	34.3	 The Tenant shall not obstruct the flow of light or air to the Property nor obstruct any means of access to the
Property. 

  

	34.4	 The Tenant shall not make any acknowledgement that the flow of light or air to the Property or that the means
of access to the Property is enjoyed with the consent of any third party. 

  

	34.5	 If any person takes or threatens to take any action to obstruct the flow of light or air to the Property or
obstruct the means of access to the Property, the Tenant shall: 

  

	 	(a)	 immediately inform the Landlord and shall give the Landlord notice of that action; and 

 

	 	(b)	 take all steps (including proceedings) the Landlord reasonably requires to prevent or secure the removal of the
obstruction. 

  

	35.	 Breach of repair and maintenance obligations 

 

	35.1	 The Landlord may enter the Property to inspect its condition and state of repair and may give the Tenant a
notice of any breach of any of the tenant covenants in this lease relating to the condition or repair of the Property. 

  

	35.2	 If the Tenant has not begun any works needed to remedy that breach within two months following that notice (or
if works are required as a matter of emergency, then immediately) or if the Tenant is not carrying out the works with all due speed, then the Landlord may enter the Property and carry out the works needed. 

 

	35.3	 The costs incurred by the Landlord in carrying out any works pursuant to this clause (and any professional fees
and any VAT in respect of those costs) shall be a debt due from the Tenant to the Landlord and payable on demand. 

  
 26 

	35.4	 Any action taken by the Landlord pursuant to this clause shall be without prejudice to the Landlord’s
other rights, including those under clause 38. 

  

	36.	 Indemnity 

The Tenant shall keep the Landlord indemnified against all liabilities, expenses, reasonable and proper costs (including but not limited to any
solicitors’ or other professionals’ reasonable and proper costs and expenses), claims, damages and losses (including but not limited to any diminution in the value of the Landlord’s interest in the Property and loss of amenity of the
Property) suffered or incurred by the Landlord arising out of or in connection with any breach of any tenant covenants in this lease, or any act or omission of the Tenant, any undertenant or their respective workers, contractors or agents or any
other person on the Property with the actual or implied authority of any of them. 
  

	37.	 Landlord’s covenant for quiet enjoyment 

The Landlord covenants with the Tenant, that, so long as the Tenant pays the rents reserved by and complies with its obligations in this lease,
the Tenant shall have quiet enjoyment of the Property without any interruption by the Landlord or any person claiming under the Landlord except as otherwise permitted by this lease. 

 

	38.	 Guarantee and indemnity 

 

	38.1	 The provisions of the Schedule apply. 

 

	38.2	 If an Act of Insolvency occurs in relation to a guarantor, or if any guarantor (being an individual) dies or
becomes incapable of managing his affairs the Tenant shall, if the Landlord requests, procure that a person of standing acceptable to the Landlord, within 28 days of that request, enters into a replacement or additional guarantee and indemnity of
the tenant covenants of this lease in the same form as that entered into by the former guarantor. 

  

	38.3	 Clause 37.2 shall not apply in the case of a person who is guarantor by reason of having entered into an
authorised guarantee agreement. 

  

	38.4	 For so long as any guarantor remains liable to the Landlord, the Tenant shall, if the Landlord requests,
procure that that guarantor joins in any consent or approval required under this lease and consents to any variation of the tenant covenants of this lease. 

  

	39.	 Re-entry and forfeiture 

 

	39.1	 The Landlord may re-enter the Property (or any part of the Property in
the name of the whole) at any time after any of the following occurs: 

  
 27 

	 	(a)	 any rent is unpaid 21 days after becoming payable whether it has been formally demanded or not;

  

	 	(b)	 any breach of any condition of, or tenant covenant in, this lease; 

 

	 	(c)	 an Act of Insolvency. 

 

	39.2	 If the Landlord re-enters the Property (or any part of the Property in
the name of the whole) pursuant to this clause, this lease shall immediately end, but without prejudice to any right or remedy of the Landlord in respect of any breach of covenant by the Tenant or any guarantor. 

 

	40.	 Joint and several liability 

 

	40.1	 Where the Tenant comprises more than one person, those persons shall be jointly and severally liable for the
obligations and liabilities of the Tenant arising under this lease. The Landlord may take action against, or release or compromise the liability of, or grant time or other indulgence to, any one of those persons without affecting the liability of
any other of them. 

  

	40.2	 Where a guarantor comprises more than one person, those persons shall be jointly and severally liable for the
obligations and liabilities of a guarantor arising under this lease. The Landlord may take action against, or release or compromise the liability of, or grant time or other indulgence to, any one of those persons without affecting the liability of
any other of them. 

  

	40.3	 The obligations of the Tenant and any guarantor arising by virtue of this lease are owed to the Landlord and
the obligations of the Landlord are owed to the Tenant. 

  

	40.4	 The Landlord shall not be liable to the Tenant for any failure of the Landlord to perform any landlord covenant
in this lease, unless and until the Tenant has given the Landlord notice of the failure and the Landlord has not remedied the failure within a reasonable time of service of that notice. 

 

	41.	 Entire agreement 

 

	41.1	 This lease constitutes the whole agreement between the parties and supersedes all previous discussions,
correspondence, negotiations, arrangements, understandings and agreements between them relating to its subject matter. 

  

	41.2	 Each party acknowledges that in entering into this lease it does not rely on, and shall have no remedies in
respect of, any representation or warranty (whether made innocently or negligently). 

  
 28 

	41.3	 Nothing in this lease constitutes or shall constitute a representation or warranty that the Property may
lawfully be used for any purpose allowed by this lease. 

  

	41.4	 Nothing in this clause shall limit or exclude any liability for fraud. 

 

	42.	 Notices, consents and approvals 

 

	42.1	 Except where this lease specifically states that a notice need not be in writing, any notice given under or in
connection with this lease shall be: 

  

	 	(a)	 in writing and for the purposes of this clause an email is not in writing; and 

 

	 	(b)	 given: 

  

	 	(i)	 by hand or by pre-paid first-class post or other next working day
delivery service at the party’s registered office address (if the party is a company) or (in any other case) at the party’s principal place of business; or 

 

	 	(ii)	 by fax to the party’s main fax number. 

 

	42.2	 If a notice complies with the criteria in clause 41,1, whether or not this lease requires that notice to be in
writing, it shall be deemed to have been received: 

  

	 	(a)	 if delivered by hand, at the time the notice is left at the proper address; 

 

	 	(b)	 if sent by pre-paid first-class post or other next working day delivery
service, on the first working day after posting; or 

  

	 	(c)	 if sent by fax, at 9.00 am on the next working day after transmission. 

 

	42.3	 This clause does not apply to the service of any proceedings or other documents in any legal action or, where
applicable, any arbitration or other method of dispute resolution. 

  

	42.4	 Section 196 of the Law of Property Act 1925 shall otherwise apply to notices given under this lease.

  

	42.5	 Where the consent of the Landlord is required under this lease, a consent shall only be valid if it is given by
deed, unless: 

  

	 	(a)	 it is given in writing and signed by the Landlord or a person duly authorised on its behalf; and

  

	 	(b)	 it expressly states that the Landlord waives the requirement for a deed in that particular case.

 If a waiver is given, it shall not affect the requirement for a deed for any other consent. 

 

	42.6	 Where the approval of the Landlord is required under this lease, an approval shall only be valid if it is in
writing and signed by or on behalf of the Landlord, unless: 

  
 29 

	 	(a)	 the approval is being given in a case of emergency; or 

 

	 	(b)	 this lease expressly states that the approval need not be in writing. 

 

	42.7	 If the Landlord gives a consent or approval under this lease, the giving of that consent or approval shall not
imply that any consent or approval required from a third party has been obtained, nor shall it obviate the need to obtain any consent or approval from a third party. 

 

	43.	 Governing law 

This lease and any dispute or claim arising out of or in connection with it or its subject matter or formation (including non-contractual disputes or claims) shall be governed by and construed in accordance with the law of England and Wales. 
  

	44.	 Jurisdiction 

Each party irrevocably agrees that the courts of England and Wales shall have exclusive jurisdiction to settle any dispute or claim arising out
of or in connection with this lease or its subject matter or formation (including non-contractual disputes or claims). 
  

	45.	 Exclusion of sections 24-28 of the LTA 1954

  

	45.1	 The parties confirm that: 

 

	 	(a)	 the Landlord served a notice on the Tenant, as required by section 38A(3)(a) of the LTA 1954, applying to the
tenancy created by this lease, before the Agreement for Lease was entered into; and 

  

	 	(b)	 [NAME OF DECLARANT] who was duly authorised by the Tenant to do so made a statutory declaration dated in
accordance with the requirements of section 38A(3)(b) of the LTA 1954. 

  

	45.2	 The parties agree that the provisions of sections 24 to 28 of the LTA 1954 are excluded in relation to the
tenancy created by this lease. 

  

	46.	 Contracts (Rights of Third Parties) Act 1999 

A person who is not a party to this lease shall not have any rights under the Contracts (Rights of Third Parties) Act 1999 to enforce any term
of this lease. This does not affect any right or remedy of a third party which exists, or is available, apart from that Act. 

  
 30 

	47.	 Tenant’s Break Option 

 

	47.1	 If the Tenant shall desire to give up possession of the Property and does not desire the tenancy created by
this lease to be continued then the Tenant may determine the term on the Break Date subject to complying with the following conditions precedent: 

  

	 	(a)	 the Tenant shall give to the Landlord not less than six months’ written notice (Break Notice) prior
to the Break Date; and 

  

	 	(b)	 as at the Break Date the Annual Rent, and any VAT in respect of it for the period prior to and up to the next
Rent Payment Date has been paid to the Landlord in full in cleared funds; and 

  

	 	(c)	 the Tenant ceases to occupy the Property on the Break Date free of any interest estate or occupation of and any
charges or mortgages created by the Tenant or any person deriving title under the Tenant, 

 THEN subject to compliance
with the aforementioned conditions precedent (but subject to the right of the Landlord to waive compliance with all or some of the conditions by giving written notice to the Tenant at any time) the term shall determine but without prejudice to the
rights and remedies of either party against the other in respect of any antecedent claim or breach of covenant or obligation AND it is agreed that time shall be of the essence for the purposes of this clause. 

 

	47.2	 If the term terminates in accordance with Clause 47.1 then within 28 days after the Break Date the Landlord
shall refund to the Tenant the proportion of the Annual Rent, and the Insurance Rent paid by the Tenant in advance relating to the period from and excluding the Break Date calculated on a daily basis. 

 

	47.3	 If the Tenant does not serve a Break Notice then for a period of sixteen months from and including the Break
Date (Half Rent Period) the Annual Rent payable under this Lease during the Half Rent Period shall be half the Annual Rent payable under this Lease (exclusive of VAT) and immediately following the expiry of the Half Rent Period the full
Annual Rent (exclusive of VAT) shall immediately become due and payable to the Landlord and to be apportioned for any period less than a full quarter. 

This document has been executed as a deed and is delivered and takes effect on the date stated at the beginning of it. 

  
 31 

 Schedule 1 Guarantee and indemnity 

 

	1.	 Guarantee and indemnity 

 

	1.1	 The Guarantor guarantees to the Landlord that the Tenant shall: 

 

	 	(a)	 pay the rents reserved by this lease and observe and perform the tenant covenants of this lease and that if the
Tenant fails to pay any of those rents or to observe or perform any of those tenant covenants, the Guarantor shall pay or observe and perform them; and 

  

	 	(b)	 observe and perform any obligations the Tenant enters into in an authorised guarantee agreement made in respect
of this lease (the Authorised Guarantee Agreement) and that if the Tenant fails to do so, the Guarantor shall observe and perform those obligations. 

  

	1.2	 The Guarantor covenants with the Landlord as principal obligor and as a separate and independent obligation and
liability from its obligations and liabilities under paragraph 1.1 to indemnify and keep indemnified the Landlord against any failure by the Tenant: 

  

	 	(a)	 to pay any of the rents reserved by this lease or any failure to observe or perform any of the tenant covenants
of this lease; or 

  

	 	(b)	 to observe or perform any of the obligations the Tenant enters into in the Authorised Guarantee Agreement.

  

	2.	 Guarantor’s liability 

 

	2.1	 The liability of the Guarantor under paragraph 1.1(a) and paragraph 1.2(a) shall continue until the end of the
term, or until the Tenant is released from the tenant covenants of this lease by virtue of the Landlord and Tenant (Covenants) Act 1995, if earlier. 

  

	2.2	 The liability of the Guarantor shall not be reduced, discharged or otherwise adversely affected by:

  

	 	(a)	 any time or indulgence granted by the Landlord to the Tenant; or 

 

	 	(b)	 any delay or forbearance by the Landlord in enforcing the payment of any of the rents or the observance or
performance of any of the tenant covenants of this lease (or the Tenant’s obligations under the Authorised Guarantee Agreement) or in making any demand in respect of any of them; or 

 

	 	(c)	 any refusal by the Landlord to accept any rent or other payment due under this lease where the Landlord
believes that the acceptance of such rent or payment may prejudice its ability to re-enter the Property; or 

  
 32 

	 	(d)	 the Landlord exercising any right or remedy against the Tenant for any failure to pay the rents reserved by
this lease or to observe or perform the tenant covenants of this lease (or the Tenant’s obligations under the Authorised Guarantee Agreement); or 

  

	 	(e)	 the Landlord taking any action or refraining from taking any action in connection with any other security held
by the Landlord in respect of the Tenant’s liability to pay the rents reserved by this lease or observe and perform the tenant covenants of the lease (or the Tenant’s obligations under the Authorised Guarantee Agreement) including the
release of any such security; or 

  

	 	(f)	 a release or compromise of the liability of any one of the persons who is the Guarantor, or the grant of any
time or concession to any one of them; or 

  

	 	(g)	 any legal limitation or disability on the Tenant or any invalidity or irregularity of any of the tenant
covenants of the lease (or the Tenant’s obligations under the Authorised Guarantee Agreement) or any unenforceability of any of them against the Tenant; or 

 

	 	(h)	 the Tenant being dissolved, or being struck off the register of companies or otherwise ceasing to exist, or, if
the Tenant is an individual, by the Tenant dying or becoming incapable of managing its affairs; or 

  

	 	(i)	 without prejudice to paragraph 4, the disclaimer of the Tenant’s liability under this lease or the
forfeiture of this lease; or 

  

	 	(j)	 the surrender of the lease in respect of part only of the Property, except that the Guarantor shall not be
under any liability in relation to the surrendered part in respect of any period after the surrender; or 

 by any other
act or omission except an express written release by deed of the Guarantor by the Landlord. 
  

	2.3	 The liability of each of the persons making up the Guarantor is joint and several. 

 

	2.4	 Any sum payable by the Guarantor shall be paid without any deduction,
set-off or counter-claim against the Landlord or the Tenant. 

  

	3.	 Variations and supplemental documents 

 

	3.1	 The Guarantor shall, at the request of the Landlord, join in and give its consent to the terms of any consent,
approval, variation or other document that may be entered into by the Tenant in connection with this lease (or the Authorised Guarantee Agreement). 

  

	3.2	 The Guarantor shall not be released by any variation of the rents reserved by, or the tenant covenants in, this
Lease (or the Tenant’s obligations under the Authorised Guarantee Agreement) whether or not: 

  
 33 

	 	(a)	 the variation is material or prejudicial to the Guarantor; or 

 

	 	(b)	 the variation is made in any document; or 

 

	 	(c)	 the Guarantor has consented, in writing or otherwise, to the variation. 

 

	3.3	 The liability of the Guarantor shall apply to the rents reserved by and the tenant covenants in this lease (and
the Tenant’s obligations under the Authorised Guarantee Agreement) as varied except to the extent that the liability of the Guarantor is affected by section 18 of the Landlord and Tenant (Covenants) Act 1995. 

 

	4.	 Guarantor to take a new lease or make payment 

 

	4.1	 If this lease is forfeited or the liability of the Tenant under this lease is disclaimed and the Landlord gives
the Guarantor notice not later than six months after the forfeiture or the Landlord having received notice of the disclaimer, the Guarantor shall enter into a new lease of the Property on the terms set out in paragraph 4.2. 

 

	4.2	 The rights and obligations under the new lease shall take effect beginning on the date of the forfeiture or
disclaimer and the new lease shall: 

  

	 	(a)	 be granted subject to the right of any person to have this lease vested in them by the court and to the terms
on which any such order may be made and subject to the rights of any third party existing at the date of the grant; 

  

	 	(b)	 be for a term that expires at the same date as the end of the Contractual Term of this lease had there been no
forfeiture or disclaimer; 

  

	 	(c)	 reserve as an initial annual rent an amount equal to the Annual Rent payable under this lease at the date of
the forfeiture or disclaimer or which would be payable but for any abatement or suspension of the Annual Rent or restriction on the right to collect it (subject to paragraph 5) and which is subject to review on the same terms and dates provided by
this lease; 

  

	 	(d)	 be excluded from sections 24 to 28 of the LTA 1954; and 

 

	 	(e)	 otherwise be on the same terms as this lease (as varied if there has been any variation).

  

	4.3	 The Guarantor shall pay the Landlord’s solicitors’ costs and disbursements (on a full indemnity
basis) and any VAT in respect of them in relation to the new lease and shall execute and deliver to the Landlord a counterpart of the new lease within one month after service of the Landlord’s notice. 

 

	4.4	 The grant of a new lease and its acceptance by the Guarantor shall be without prejudice to any other rights
which the Landlord may have against the Guarantor or against any other person or in respect of any other security that the Landlord may have in connection with this lease. 

  
 34 

	4.5	 The Landlord may, instead of giving the Guarantor notice pursuant to paragraph 4.1 but in the same
circumstances and within the same time limit, require the Guarantor to pay an amount equal to six months Annual Rent and the Guarantor shall pay that amount on demand. 

 

	5.	 Rent at the date of forfeiture or disclaimer 

If at the date of the forfeiture or disclaimer there is a rent review pending under this lease, then the initial annual rent to be reserved by
the new lease shall be the greater of: 
  

	 	(a)	 the Annual Rent previously payable (or which would have been payable but for any abatement or suspension of the
Annual Rent or restriction on the right to collect it) under the lease prior to forfeiture or disclaimer; and 

  

	 	(b)	 the open market rent of the Property at the Review Date, as determined by the Landlord before the grant of the
new lease. 

  

	6.	 Payments in gross and restrictions on the Guarantor 

 

	6.1	 Any payment or dividend that the Landlord receives from the Tenant (or its estate) or any other person in
connection with any insolvency proceedings or arrangement involving the Tenant shall be taken and applied as a payment in gross and shall not prejudice the right of the Landlord to recover from the Guarantor to the full extent of the obligations
that are the subject of this guarantee and indemnity. 

  

	6.2	 The Guarantor shall not claim in competition with the Landlord in any insolvency proceedings or arrangement of
the Tenant in respect of any payment made by the Guarantor pursuant to this guarantee and indemnity. If it otherwise receives any money in such proceedings or arrangement, it shall hold that money on trust for the Landlord to the extent of its
liability to the Landlord. 

  

	6.3	 The Guarantor shall not, without the consent of the Landlord, exercise any right or remedy that it may have
(whether against the Tenant or any other person) in respect of any amount paid or other obligation performed by the Guarantor under this guarantee and indemnity unless and until all the obligations of the Guarantor under this guarantee and indemnity
have been fully performed. 

  

	7.	 Other securities 

 

	7.1	 The Guarantor warrants that it has not taken and covenants that it shall not take any security from or over the
assets of the Tenant in respect of any liability of the Tenant to the Guarantor. If it does take or hold any such security it shall hold it for the benefit of the Landlord. 

  
 35 

	7.2	 This guarantee and indemnity is in addition to and independent of any other security that the Landlord may from
time to time hold from the Guarantor or the Tenant or any other person in respect of the liability of the Tenant to pay the rents reserved by this lease and to observe and perform the tenant covenants of this lease. It shall not merge in or be
affected by any other security. 

  

	7.3	 The Guarantor shall not be entitled to claim or participate in any other security held by the Landlord in
respect of the liability of the Tenant to pay the rents reserved by this lease or to observe and perform the tenant covenants of this lease. 

  
 36 

							
	EXECUTED as a DEED by	  	)	  	
	PROVOST 1 LIMITED	  	)	  	  

	acting by a Director in the presence of:	  	)	  	Director
		
	Witness:	 	
	Signature:	 	  

	Name:	 	  

	Address:	 	  

		 	  

		 	  

	Occupation:	 	  

			
	EXECUTED as a DEED by	  	)	  	
	PROVOST 2 LIMITED	  	)	  	  

	acting by a Director in the presence of:	  	)	  	Director
				
	Witness:	 		  		  	
	Signature:	 	  

	Name:	 	  

	Address:	 	  

		 	  

		 	  

	Occupation:	 	  

			
	EXECUTED as a DEED by	  	)	  	
	MEIRAGTX UK II LTD	  	)	  	  

	acting by a Director in the presence of:	  	)	  	Director
				
	Witness:	 		  		  	
	Signature:	 	  

	Name:	 	  

	Address:	 	  

		 	  

		 	  

	Occupation:	 	  

  
 37

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00298-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00298-of-00352.parquet"}]]