Document:

Form of Series B Preferred Stock Warrant

 Exhibit 10.21 
 THIS WARRANT AND THE SECURITIES ISSUABLE UPON EXERCISE OF THIS WARRANT HAVE NOT BEEN REGISTERED UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED OR UNDER THE SECURITIES LAWS OF ANY STATE. THESE SECURITIES HAVE BEEN ACQUIRED FOR
INVESTMENT AND NOT WITH A VIEW TO DISTRIBUTION OR RESALE, AND MAY NOT BE MORTGAGED, PLEDGED, HYPOTHECATED OR OTHERWISE TRANSFERRED WITHOUT AN EFFECTIVE REGISTRATION STATEMENT FOR SUCH SECURITIES UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR AN
OPINION OF COUNSEL SATISFACTORY TO THE COMPANY THAT REGISTRATION IS NOT REQUIRED UNDER SUCH ACT AND UNDER ANY SUCH APPLICABLE STATE LAWS, PROVIDED SUCH OPINION REQUIREMENT WILL BE WAIVED IN THE REASONABLE DISCRETION OF THE COMPANY. 

TARGANTA THERAPEUTICS CORPORATION 
 Warrant to Subscribe for Series B Preferred Stock 
 ___________________ 
 Introduction 
 Whereas, prior to the issuance of this warrant, under an
Offer of Loan, dated as of April 27, 2004, as amended from time to time, the Holder (as defined below) held an option to acquire Class B Exchangeable Shares of Targanta Québec (as defined below), which such Class B Exchangeable Shares
are exchangeable by their terms into Series B Preferred Stock of the Company (as defined below) at the option of the holder thereof or upon the occurrence of certain events; 
 Whereas, in connection with the full repayment of the loan extended by the Holder to Targanta Québec and the issuance of this warrant, the
Offer of Loan is being terminated in its entirety; and 
 Whereas, in consideration of the foregoing, the Company (as defined below)
desires to issue this warrant to the Holder to replace the option included within the Offer of Loan, which option and Offer of Loan are being terminated. 
  

	1.	Certification 

 THIS CERTIFIES THAT, for value received,
_____________________ (together with any permitted transferees or assignees, herein referred to as the “Holder”) is entitled to subscribe for and purchase up to _____________________ fully paid and non-assessable shares of Series B
Preferred Stock (as hereinafter defined) (as adjusted or changed pursuant to the provisions hereof, the “Warrant Shares”) of Targanta Therapeutics Corporation (the “Company”), a corporation incorporated under the
laws of Delaware and having its principal offices at 222 Third Avenue, Suite 2300, Cambridge, Massachusetts 02142, at a price per share of _____________(as adjusted pursuant to the provisions hereof, the “Exercise Price”), subject
to the provisions and upon the terms and conditions hereinafter set forth. 

	2.	Definitions 

 As used herein: 
  

	 	(a)	“Business Day” means any day except Saturday, Sunday or any statutory or civic holiday in the Provinces of Quebec or Ontario or the State of New York;

  

	 	(b)	“Certificate of Incorporation” means the Company’s certificate of incorporation, as amended or restated from time to time. 

  

	 	(c)	“Common Stock” means the common stock, par value US$0.0001 per share, in the capital of the Company, as constituted from time to time; 

  

	 	(d)	“Convertible Security” means a security convertible into or exchangeable, directly or indirectly, for any share of Series B Preferred Stock;

  

	 	(e)	“Fair Market Value per share of Series B Preferred Stock” means the product of: 

  

	 	(i)	the number of shares of Common Stock issuable upon conversion of a share of Series B Preferred Stock; and 

  

	 	(ii)	the Market Price per share of Common Stock on the record date of the Special Distribution or, if the record date of the Special Distribution is not a Business Day, on the next
succeeding Business Day; provided that if there has not been a Special Distribution, the Market Price per share of Common Stock shall be determined as of the day immediately prior to the date on which this Warrant is exercised;

  

	 	(f)	“Market Price” per share of Common Stock shall mean: 

  

	 	(i)	if the Special Distribution is in connection with a Qualified Public Offering, then the initial per share price to the public specified in the final prospectus with respect to such
offering; or 

  

	 	(ii)	if the Special Distribution is not in connection with and contingent upon a transaction referred to in Section 2(f)(i) or if there has not been a Special Distribution, then as
follows: 

  

	 	A.	if the Common Stock is traded on a Qualified Exchange, the Market Price shall be the volume weighted average sale price of the Common Stock on such exchange on the last 20
consecutive trading days (or all such trading days such Common Stock has been traded if fewer than 20 trading days) immediately preceding the record date of the Special Distribution; or 

  

	 	B.	 if the Common Stock is not so traded, the Market Price shall be the price per share which the Company could obtain from a 

	 	 
willing buyer for shares sold by the Company from authorized but unissued shares, and such price shall be determined by the board of directors of the Company
acting in good faith; 

  

	 	(g)	“Permitted Transferee” means any transferee permitted by Section 5.2 of the Principal Shareholders Agreement; 

  

	 	(h)	“Principal Shareholders Agreement” means the Amended and Restated Agreement Among Principal Shareholders, dated as of January 31, 2007, by and among the
Company, Targanta Québec, Targanta Ontario and certain of their stockholders, as amended from time to time. 

  

	 	(i)	“Qualified Exchange” means the NASDAQ Global Market or such other recognized stock exchange acceptable to the Company; and 

  

	 	(j)	“Qualified Public Offering” has the meaning ascribed thereto in the Certificate of Incorporation. 

  

	 	(k)	“Series B Preferred Stock” means the Series B Preferred Stock, par value US$0.0001 per share, in the capital of the Company, as constituted from time to time;

  

	 	(l)	“Shareholders Agreements” means the Principal Shareholders Agreement and the Unanimous Shareholders Agreement. 

  

	 	(m)	“Targanta Québec” means Targanta Therapeutics Inc., a corporation organized under the Canada Business Corporations Act. 

  

	 	(n)	“Targanta Ontario” means Targanta Therapeutics (Ontario) Inc, a corporation organized under the Canada Business Corporations Act. 

  

	 	(o)	“Unanimous Shareholders Agreement” means the Amended and Restated Unanimous Shareholders Agreement, dated as of January 31, 2007, by and among the Company,
Targanta Québec, Targanta Ontario and all of their stockholders, as amended from time to time. 

  

	3.	Exercise Period 

 Subject to the terms and conditions set forth
herein, this Warrant may be exercised, in whole or in part, by the Holder at any time from and after the date hereof and prior to the first anniversary hereof (the “Exercise Period”). 
  

	4.	Transferability 

 This Warrant is transferable in whole or in part
by the Holder, in person or by its duly authorized attorney to a Permitted Transferee of the Holder upon surrender at the registered office of the Company of this Warrant certificate together with a duly executed form of assignment acceptable to the
Company, acting reasonably. Upon surrender of this Warrant certificate to the 

 
Company in proper form for transfer, as required hereby and provided that the other terms and conditions set forth in Section 5.2 of the Principal
Shareholders Agreement have been fulfilled, the Company shall issue a new Warrant certificate or certificates in the same form and of like tenor as this Warrant certificate representing the right to subscribe for and purchase, in the aggregate, the
number of Warrant Shares that may be subscribed for and purchased hereunder and, individually, the number of Warrant Shares the right to purchase which has been so transferred to each transferee and which has been retained by the transferor, if any.
A transfer of this Warrant will be deemed not to have been completed until the Permitted Transferee shall have entered into an agreement agreeing to be bound by the Principal Shareholders Agreement and the Unanimous Shareholders Agreement.

  

	5.	Exercise of Warrant 

 Subject to the terms and conditions set forth
herein, this Warrant may be exercised at any time, in whole or in part, by the Holder during the Exercise Period by: 
  

	 	(a)	The presentation and surrender of this Warrant certificate to the Company at its principal office, with either: 

  

	 	(i)	a duly executed subscription form in the form annexed hereto as Schedule A and payment to the Company, by cash, wire transfer of immediately available funds, certified check
or any other means approved by the Company of the aggregate Exercise Price; or 

  

	 	(ii)	a duly executed redemption notice in the form annexed hereto as Schedule B stating that the Holder elects to receive, without the payment by the Holder of any additional
consideration, fully paid and nonassessable shares equal to the value of this Warrant or any portion hereof computed using the following formula: 

 X = Y (A-B) 
 A 
  

			
	 where X =
	    	the number of shares to be issued to the Holder pursuant to this Section 5(a)(ii).
		
	Y =	    	the number of shares covered by this Warrant in respect of which the net issue election is made pursuant to this Section 5(a)(ii).
		
	A =	    	the fair market value of one share of Series B Preferred Stock, as determined below, as at the time the net issue election is made pursuant to this Section 5(a)(ii).
		
	B =	    	the Purchase Price in effect under this Warrant at the time the net issue election is made pursuant to this Section 5(a)(ii).

 For the purposes of this Section 5(a)(ii), fair market value shall be determined at the time of
exercise and in the same manner as used for calculating the Fair Market Value per share of Series B Preferred Stock. 
  

	 	(b)	Upon receipt by the Company of this Warrant certificate and (i) an executed subscription form together with proper payment of such Exercise Price as aforesaid or (ii) an
executed redemption notice pursuant to Section 5(a)(ii) hereof, the Company agrees that the Warrant Shares shall be deemed to be issued to the Holder as the record holder of such Warrant Shares as of the close of business on the date on which
this Warrant certificate shall have been surrendered and, in the case of an exercise pursuant to Section 5(a)(i) above, payment made for the Warrant Shares as aforesaid (the “Exercise Date”). In the event of any exercise of the
rights represented by this Warrant, certificates for the Warrant Shares so purchased shall be delivered to the Holder as soon as practicable, but not later than five Business Days after exercise. In the event that the Holder subscribes for and
purchases or redeems less than the full number of Warrant Shares entitled to be subscribed for and purchased or redeemed under this Warrant prior to the end of the Exercise Period, the Company shall issue a new warrant certificate to the Holder, at
no charge, in the same form as this Warrant certificate with appropriate changes as to the number of Warrant Shares that the holder thereof is entitled to subscribe for and purchase or redeem thereunder. 

  

	6.	Limitation of Rights 

 Nothing contained in this Warrant certificate
shall be construed as conferring upon the Holder any right or interest whatsoever as a holder of Warrant Shares or any other right or interest except as herein expressly provided. 
  

	7.	Adjustments 

  

	 	(a)	 In case of any reclassification of the Series B Preferred Stock or change of the Series B Preferred Stock into other shares, or in case of the consolidation,
merger, reorganization or amalgamation of the Company with or into any other corporation or entity which results in any reclassification of the Series B Preferred Stock or a change of the Series B Preferred Stock into other shares, or in case of any
transfer of the undertaking or assets of the Company as an entirety or substantially as an entirety to another person (any such event being hereinafter referred to as a “Reclassification of Series B Preferred Stock” and any other
corporation or entity or person referred to above being hereinafter referred to as a “Successor Company”), at any time prior to the expiry of the Exercise Period, the Holder shall, after the effective date of such Reclassification
of Series B Preferred Stock, be entitled to receive, and shall accept, in lieu of the number of Warrant Shares to which the Holder was theretofore entitled upon such exercise, the kind and amount of shares and other securities or property that the
Holder would have been entitled to receive as a result of such Reclassification of Series B Preferred Stock if, on the effective date thereof, the Holder had been the registered holder of the number of Warrant Shares to which the Holder was 

	 	 
theretofore entitled upon such exercise. The Company shall ensure that the Successor Company enters into an agreement with the Holder confirming the
Holder’s rights pursuant to this Section 7(a) and providing for adjustments, which shall be as nearly equivalent as may be practicable to the adjustments provided for in this Section 7. 

  

	 	(b)	If and whenever at any time prior to the expiry of the Exercise Period the Company shall: 

  

	 	(i)	subdivide or redivide the outstanding Series B Preferred Stock into a greater number of shares; 

  

	 	(ii)	reduce, combine or consolidate the outstanding Series B Preferred Stock into a lesser number of shares; or 

  

	 	(iii)	issue Series B Preferred Stock or Convertible Securities to the holders of all or substantially all of the outstanding Series B Preferred Stock by way of a stock dividend or other
distribution on the Series B Preferred Stock payable in Series B Preferred Stock or Convertible Securities; 

 (any such event
being hereinafter referred to as a “Capital Reorganization”) and any such event results in an adjustment in the Exercise Price pursuant to Section 7(c), or if there is a Special Distribution and such Special Distribution
results in an adjustment in the Exercise Price pursuant to Section 7(d) the number of Warrant Shares purchasable pursuant to this Warrant shall be adjusted upwards or downwards, as the case may be, contemporaneously with the adjustment of the
Exercise Price by multiplying the number of Warrant Shares theretofore purchasable on the exercise hereof by a fraction the numerator of which shall be the Exercise Price in effect immediately prior to such adjustment and the denominator of which
shall be the Exercise Price resulting from such adjustment. 
  

	 	(c)	If and whenever at any time prior to the expiry of the Exercise Period, the Company shall engage in a Capital Reorganization, the Exercise Price shall, in the case of a subdivision,
redivision, reduction, combination or consolidation, on the relevant effective date, or in the case of a stock dividend, on the record date, be adjusted by multiplying the Exercise Price in effect on such effective date or record date by a fraction:

  

	 	A.	the numerator of which shall be the number of Series B Preferred Stock outstanding before giving effect to such Capital Reorganization; and 

  

	 	B.	the denominator of which is the number of Series B Preferred Stock outstanding after giving effect to such Capital Reorganization including after giving effect to the deemed
conversion into or exchange for Series B Preferred Stock of any Convertible Securities distributed by way of stock dividend or other such distribution referred to above. 

 Such adjustment shall be made successively whenever any event referred to in this Section 7(c) shall
occur. Any such issue of Series B Preferred Stock by way of a stock dividend shall be deemed to have been made on the record date fixed for such stock dividend for the purpose of calculating the number of outstanding Series B Preferred Stock.

  

	 	(d)	Other than in connection with a Capital Reorganization, if and whenever at any time prior to the expiry of the Exercise Period, the Company shall fix a record date for the
distribution to all or substantially all the holders of Series B Preferred Stock of: 

  

	 	(i)	shares of any class, whether of the Company or any other corporation: 

  

	 	(ii)	rights, options or warrants; 

  

	 	(iii)	evidences of indebtedness; or 

  

	 	(iv)	other assets or property (excluding cash dividends paid to the holders of Series B Preferred Stock in accordance with the Certificate of Incorporation); 

 (any such event being hereinafter referred to as a “Special Distribution”) the Exercise Price shall be adjusted immediately after such
record date so that it shall equal the price determined by multiplying the Exercise Price in effect on such record date by a fraction: 
  

	 	(v)	the numerator of which shall be the amount by which: 

  

	 	A.	the amount obtained by multiplying the number of shares of Series B Preferred Stock outstanding on such record date by the Fair Market Value per share of Series B Preferred
Stock on such record date; exceeds 

  

	 	B.	the fair market value as determined by resolution of the board of directors of the Company, subject to the prior consent of any stock exchange or market upon which the Series B
Preferred Stock or Common Stock are listed and posted for trading or quoted on (each, an “Exchange”), if required, of such Special Distribution to the holders of such Series B Preferred Stock; and 

  

	 	(vi)	the denominator of which shall be the total number of shares of Series B Preferred Stock outstanding on such record date multiplied by such Fair Market Value per share of Series B
Preferred Stock on such record date. 

 Such adjustment shall be made successively whenever such a record date is fixed. To the extent that such
Special Distribution is not so made or any such rights, options or warrants are not exercised prior to the expiration thereof, the Exercise Price shall then be readjusted to the Exercise Price which would then be in effect if such record date had
not been fixed or if such expired rights, options or warrants had not been issued. 
  

	 	(e)	In any case in which this Section 7 shall require that an adjustment shall become effective immediately after a record date for an event referred to herein, the Company may
defer, until the occurrence of such event, issuing to the Holder, upon the exercise of this Warrant after such record date and before the occurrence of such event, the additional Warrant Shares issuable upon such exercise by reason of the adjustment
required by such event, provided, however, that the Company shall deliver to the Holder an appropriate instrument evidencing the Holder’s right to receive such additional Warrant Shares upon the occurrence of the event requiring such adjustment
and the right to receive any distributions made on such additional Warrant Shares on and after such exercise. 

  

	 	(f)	The adjustments provided for in this Section 7 are cumulative and shall, in the case of adjustments to the Exercise Price, be computed to the nearest one-tenth of one cent and
shall apply (without duplication) to successive Reclassifications of Series B Preferred Stock, Capital Reorganizations and Special Distributions, provided that, notwithstanding any other provision of this Section 7, no adjustment of the
Exercise Price shall be required unless such adjustment would require a decrease or increase of at least 1% of the Exercise Price then in effect (provided, however, that any adjustments that by reason of this paragraph are not required to be made
shall be carried forward and taken into account in any subsequent adjustment). 

  

	 	(g)	No adjustment in the number of Warrant Shares which may be purchased upon exercise of this Warrant or in the Exercise Price shall be made pursuant to this Warrant certificate if the
Holder is entitled to participate in such event on the same terms mutatis mutandis as if the Holder had exercised this Warrant for Warrant Shares prior to the effective date or record date of such event, such participation subject to the prior
consent of any stock exchange, if required. 

  

	 	(h)	As a condition precedent to the taking of any action that would require an adjustment in the subscription rights pursuant to this Warrant certificate, including the Exercise Price
and the number of classes of shares or other securities or property that are to be received upon the exercise thereof, the Company shall take any corporate action that may, in the opinion of counsel, be necessary in order that the Company has
unissued and reserved in its authorized capital and may validly and legally issue as fully paid and non-assessable all the shares of such classes or other securities or may validly and legally distribute the property that the Holder is entitled to
receive on the full exercise thereof in accordance with the provisions hereof. 

	 	(i)	At least 14 days prior to the effective date or record date, as the case may be, of any event that requires an adjustment in the subscription rights pursuant to this Warrant
certificate, including the Exercise Price and the number and classes of shares or other securities or property that are to be received upon the exercise thereof, the Company shall give notice to the Holder of the particulars of such event and the
required adjustment. 

  

	 	(j)	If any event occurs in respect of which the foregoing provisions of this Section 7 may not be applicable but which could have an effect on the Series B Preferred Stock or the
purchase rights applicable to this Warrant certificate, then the board of directors of the Company shall make such adjustments as are necessary in accordance with the essential intent and principles of such provisions, as shall be reasonably
necessary, in the good faith opinion of such board of directors of the Company, to protect the purchase rights of this Warrant certificate. 

  

	8.	Limited Redemption Right 

  

	 	(a)	Provided that the Holder has exercised this Warrant prior to the date on which the Company effects an initial public offering of its Common Stock, on thirty (30) days prior
written notice to the Company, the Holder may require the Company to redeem the shares of Series B Preferred Stock issued to the Holder upon exercise of this Warrant; provided that the Company shall only be required to effect such redemption
of such shares of Series B Preferred Stock if, as of the date on which such redemption would be required (the “Redemption Date”), the Company has not then effected an initial public offering of its Common Stock. For purposes of
clarity, if, prior to the Redemption Date, the shares of Series B Preferred Stock issued upon exercise of this Warrant have been converted into Common Stock, the provisions of this Article 8 shall be deemed to apply to such shares of Common Stock on
an as-converted basis and the provisions of this Article 8 shall be adjusted as necessary to reflect the conversion of such shares of Series B Preferred Stock into shares of Common Stock. 

  

	 	(b)	The price at which the Company shall be required to effect any redemption of the shares of its Series B Preferred Stock issued to the Holder upon the Holder’s exercise of this
Warrant shall be the greater of: 

  

	 	(i)	The price of such shares of Series B Preferred Stock based on the book value of the Company established according to its consolidated, audited, annual financial statements for the
fiscal year preceding the Redemption Date, plus the Company’s net earnings after taxes established according to its consolidated, audited, annual financial statements for the two (2) fiscal years preceding the Redemption Date;

  

	 	(ii)	 The highest price paid for any such shares of Series B Preferred Stock by anyone who has subscribed for a minimum amount of One Million Dollars ($1,000,000) in the
two (2) fiscal years of the Company 

	 	 
preceding the Redemption Date or on the verge of being paid under an offer to purchase accepted by the Company as of the Redemption Date;

  

	 	(iii)	The unit market value of such shares of Series B Preferred Stock as of the date on which the Company received the Holder’s request for redemption, it being understood that this
value shall be established on the basis of generally accepted valuation principles in the United States as are usually applied to establish the value per share of the Company’s capital stock within the context of a round of financing and taking
into account the special conditions of the biotechnology industry. Notwithstanding the foregoing, it is understood that no discount (including the discount for minority position or for lack of liquidity) shall be charged to the market valuation. In
the event that the Company and the Holder cannot agree on the market value of the shares for which the Holder is seeking redemption within fifteen (15) days of receipt by the Company of the Holder’s request for redemption, then the market
value shall be determined by the engagement by the Company of a qualified valuation firm, with the costs of such exercise borne equally by the Company and the Holder. 

 For purposes of clarity, the Company’s financial statements shall be prepared in accordance with generally accepted accounting principles as in
effect in the United States from time to time. 
  

	9.	Fractional Shares 

 The Company shall not be required to issue
fractional Warrant Shares upon the exercise of this Warrant. If any fractional interest in a Warrant Share would, except for the provisions of this Section, be deliverable upon the exercise of this Warrant, the Company shall, in lieu of delivering
any certificate for such fractional interest, satisfy such fractional interest by delivering to the Holder a certificate representing one Warrant Share or an amount in readily available funds equal to the fair value (as determined in good faith by
the board of directors of the Company) of such fractional interest (which fair value shall at least initially be the original issue price per share of the Series B Preferred Stock). 
  

	10.	Covenants of Company 

 Prior to the expiry of the Exercise Period:

  

	 	(a)	 The Company shall at all times reserve and keep available free from pre-emptive rights, out of the aggregate of its authorized but unissued Series B Preferred Stock
and Common Stock, for the purpose of enabling it to satisfy any obligation to issue shares of Series B Preferred Stock upon exercise of this Warrant or shares of Common Stock upon conversion of any such shares of Series B Preferred Stock, the full
number of shares of Series B Preferred Stock and Common Stock deliverable upon the exercise or conversion thereof, as the case may be. The Company covenants that all Warrant Shares which may be issued upon exercise 

	 	 
of this Warrant and payment therefor and all shares of Common Stock which may be issued upon conversion of the Warrant Shares, will upon issue be fully paid
and non-assessable. 

  

	 	(b)	Subject to applicable laws, the Company shall from time to time take all action which may be necessary to obtain and keep effective any and all permits, consents and approvals of
governmental agencies and authorities and shall make all securities acts filings under United States or Canadian federal, state or provincial laws, which may be or become requisite in connection with the issuance and exercise of this Warrant.

  

	 	(c)	Upon receipt of evidence satisfactory to the Company of the loss, theft, destruction or mutilation of this Warrant certificate, and (in the case of loss, theft or destruction) of
indemnification satisfactory to the Company, and upon surrender and cancellation of this Warrant certificate, if mutilated, the Company shall execute and deliver a new Warrant certificate of like tenor and date. 

  

	11.	Enforcement of Rights 

 All or any of the rights conferred upon the
Holder hereunder may be enforced by such Holder by appropriate legal proceedings. 
  

	12.	Representations and Covenants of Holder 

 The Holder hereby
represents, covenants and agrees as follows: 
  

	 	(a)	to abide by and comply with all legal and policy requirements of any governmental body, securities regulatory authority or stock exchange, applicable to any offer, sale, trade,
transfer or assignment of this Warrant and/or any of the Warrant Shares issued upon the exercise of this Warrant, whether in whole or in part; 

  

	 	(b)	not to offer, trade, sell, assign or otherwise transfer this Warrant nor any of the Warrant Shares into which this Warrant may be exercised other than in accordance with the
provisions of this Warrant certificate; 

  

	 	(c)	to abide by and comply with the terms of the Shareholders Agreements in respect of any Warrant Shares received upon exercise of this Warrant and Common Stock deliverable upon the
conversion of the Warrant Shares; 

  

	 	(d)	if the Holder is a resident of Canada, he or it is an “accredited investor” as defined in National Instrument 45-106 Prospectus and Registration Exemptions of the Canadian
Securities Administrators; 

  

	 	(e)	he or it is an “accredited investor” as such term is defined in Rule 501(a) promulgated under the United States Securities Act of 1933, as amended; and

	 	(f)	if not already a party to the Unanimous Shareholders Agreement, upon exercise of this Warrant, the Holder covenants and agrees to become a party to such agreement.

  

	13.	General 

  

	 	(a)	The Company will not, by amendment of its Certificate of Incorporation or through any reorganization, transfer of assets, consolidation, merger, dissolution, issue or sale of
securities or any other action, avoid or seek to avoid the observance or performance of any of the terms of this Warrant certificate, but will at all times in good faith assist in the carrying out of all such terms and in the taking of all such
action as may be necessary or appropriate in order to protect the rights of the Holder under this Warrant. 

  

	 	(b)	Neither this Warrant certificate nor any term hereof may be amended, waived, discharged or terminated other than by an instrument in writing signed by the Company and by the Holder
hereof. 

  

	 	(c)	Any notice, request or other document required or permitted to be given or delivered to the Holder hereof or the Company shall be delivered or shall be sent by certified mail,
confirmed facsimile or personal delivery, to the Holder at the Holder’s address as shown on the books of the Company or to the Company at the address indicated therefor in Section 1 of this Warrant certificate or such other address as the
Company shall have notified the Holder. 

  

	 	(d)	The descriptive headings of the several sections and paragraphs of this Warrant certificate are inserted for convenience only and do not constitute a part of this Warrant
certificate. 

  

	 	(e)	This Warrant shall terminate and the provisions hereof shall be of no further force and effect at the expiry of the Exercise Period. 

  

	 	(f)	Time shall be of the essence of this Warrant. 

  

	 	(g)	The Company and the Holder shall from time to time take or cause to be taken such action and execute and deliver or cause to be executed and delivered such documents and such
further assurances as may be necessary or advisable to give effect to the provisions hereof. 

  

	 	(h)	This Warrant and the rights hereunder shall be governed by and construed in accordance with the laws of the State of Delaware. 

  

	 	(i)	 For the avoidance of doubt, the shares issuable upon exercise of this Warrant shall be entitled to the rights provided under the Company’s Amended and Restated
Registration Rights Agreement, by and among the Company and the other parties thereto, dated as of January 31, 2007, as amended from time to time. In addition, if, prior to the exercise of this Warrant, all of the outstanding shares of the
Series 

	 	 
B Preferred Stock are converted into shares of Common Stock, this Warrant shall instead be exercisable for that number of shares of Common Stock as the
shares of Series B Preferred Stock for which this Warrant was originally exercisable would convert into based on the applicable conversion ratio, as provided in the Certificate of Incorporation, at the time of such conversion.

 [Remainder of Page Intentionally Left Blank.] 

 IN WITNESS WHEREOF the Company has caused this Warrant certificate to be executed by its duly
authorized officer on the date first written above. 
  

			
	TARGANTA THERAPEUTICS CORPORATION
		
	By:	 	 
	Name:	 	George Eldridge
	Title:	 	Treasurer and Assistant Secretary

 SCHEDULE A 
 SUBSCRIPTION FORM 
  

	TO:	Targanta Therapeutics Corporation 

 ____________________________ 
 ____________________________ 
 ____________________________ 
 ____________________________ 
 The undersigned holder of the attached warrant (the “Warrant”) to purchase Series B Preferred Stock
of Targanta Therapeutics Corporation (the “Company”) hereby irrevocably elects to subscribe for shares of Series B Preferred Stock of the Company issuable pursuant to the Warrant on the terms specified in the Warrant certificate and
tenders herewith payment of the purchase price of such shares in full. 
 The undersigned acknowledges that within five business days of receipt of the
Warrant certificate together with this subscription form, provided same has been duly completed and executed, the Company will deliver or cause to be delivered to the undersigned, as specified below, a certificate representing the Series B Preferred
Stock of the Company subscribed for hereunder. 
 The undersigned covenants and agrees to comply with the covenants of the undersigned set out in the Warrant
certificate. 
 DATED this                     
day of                     , 200    . 
  

			
	
	 
	Name of Warrantholder
		
	By:	 	 
		 	Authorized Signatory
	
	Address in Full                                 
                                       
 
	
	  

 SCHEDULE B 
 REDEMPTION NOTICE 
  

	TO:	Targanta Therapeutics Corporation 

 ____________________________ 
 ____________________________ 
 ____________________________ 
 ____________________________ 
 The undersigned holder of the attached warrant (the “Warrant”) to purchase shares
of Series B Preferred Stock of Targanta Therapeutics Corporation (the “Company”), hereby irrevocably elects, in accordance with and subject to the provisions of Section 5(a)(ii) of such Warrant, to redeem, and to cause the
Company to redeem, such Warrant with respect to that portion of such Warrant representing __________ underlying shares of Series B Preferred Stock of the Company. The undersigned requests that the certificates for the shares of Series B
Preferred Stock issuable upon redemption be issued in the name of, and delivered to ____________________________, whose address is __________________________________. 
 DATED this                      day of
                    , 200    . 
  

			
	
	 
	Name of Warrantholder
		
	By:	 	 
		 	Authorized Signatory
	
	Address in FullCredit and Security Agreement

 Exhibit 10.22 
 CREDIT AND SECURITY AGREEMENT 
 THIS CREDIT AND SECURITY AGREEMENT (as the same may be
amended, supplemented, restated or otherwise modified from time to time, the “Agreement”) is dated as of September 24, 2007 by and among (a) TARGANTA THERAPEUTICS CORPORATION, a Delaware corporation, and any
additional Borrower that may hereafter be added to this Agreement (each individually as a “Borrower” and collectively as “Borrowers”), (b) MERRILL LYNCH CAPITAL, a division of Merrill Lynch Business
Financial Services Inc., individually as a Lender, and as Administrative Agent, (c) OXFORD FINANCE CORPORATION, a Delaware corporation, as a Lender, and (d) BLUECREST CAPITAL FINANCE, L.P., a Delaware limited partnership, as
a Lender, and (e) the financial institutions or other entities from time to time parties hereto, each as a Lender. 
 RECITALS 

 Borrowers have requested that Lenders make available to Borrowers the financing facilities as described herein. Lenders are willing to
extend such credit to Borrowers under the terms and conditions herein set forth. 
 AGREEMENT 
 NOW, THEREFORE, in consideration of the premises and the agreements, provisions and covenants herein contained, Borrowers, Lenders and
Administrative Agent agree as follows: 
 ARTICLE 1 - DEFINITIONS 
 Section 1.1 Certain Defined Terms. 
 The following terms have the following meanings: 
 “Account Debtor” means “account debtor”, as defined in
Article 9 of the UCC, and any other obligor in respect of an Account. 
 “Accounts” means collectively any
“account” (as defined in Article 9 of the UCC), any accounts receivable (whether in the form of payments for services rendered or goods sold, rents, license fees or otherwise), any “payment intangibles” (as defined in Article 9
of the UCC), and IP Proceeds and all other rights to payment and/or reimbursement of every kind and description, whether or not earned by performance, and all proceeds of any of the foregoing. 
 “Administrative Agent” means Merrill Lynch, in its capacity as administrative agent for the Lenders hereunder, as such capacity is
established in, and subject to the provisions of, Article 11, and the successors of Merrill Lynch in such capacity. 
 “Affiliate” means with respect to any Person (a) any Person that directly or indirectly controls such Person, (b) any Person which is controlled by or is under common control with such controlling Person, and
(c) each of such Person’s (other than, with respect to any Lender, any Lender’s) officers or directors (or Persons functioning in substantially similar roles) and the spouses, parents, descendants and siblings of such officers,
directors or other Persons. As used in this definition, the term “control” of a Person means the possession, directly or indirectly, of the power to vote five percent (5%) or more of any class of voting securities of such Person or to
direct or cause the direction of the management or policies of a Person, whether through the ownership of voting securities, by contract or otherwise. 
 “Anti-Terrorism Laws” means any Laws relating to terrorism or money laundering, including Executive Order No. 13224 (effective September 24, 2001), the USA PATRIOT Act, the Laws comprising
or implementing the Bank Secrecy Act, and the Laws administered by OFAC. 
 “Approved Assignee” means any
(a) investment company, banking institution, lending institution, fund, trust, securitization vehicle or conduit that is (or will be) engaged in making, purchasing, holding or otherwise 

 
investing in commercial loans and similar extensions of credit in the healthcare, life sciences or technology industries in the ordinary course of its
business, which assignee has been consented to by the Required Lenders, which consent may not be unreasonably withheld, conditioned or delayed, and (b) any Affiliate of a Lender which is in the same line of business as such Lender. 

“Asset Disposition” means any sale, lease, license, transfer, assignment or other consensual disposition by any Credit Party of any
asset. 
 “Assignment Agreement” means an agreement substantially in the form of Exhibit A hereto.

 “Bankruptcy Code” means Title 11 of the United States Code entitled “Bankruptcy”, as the same may be amended,
modified or supplemented from time to time, and any successor statute thereto. 
 “Base Rate” means the LIBOR Rate.

 “Base Rate Margin” means 6.0% per annum with respect to the Term Loan and other Obligations. 
 “Blocked Person” means any Person: (a) listed in the annex to, or is otherwise subject to the provisions of, Executive Order
No. 13224, (b) owned or controlled by, or acting for or on behalf of, any Person that is listed in the annex to, or is otherwise subject to the provisions of, Executive Order No. 13224, (c) with which any Lender is prohibited
from dealing or otherwise engaging in any transaction by any Anti-Terrorism Law, (d) that commits, threatens or conspires to commit or supports “terrorism” as defined in Executive Order No. 13224, or (e) that is named a
“specially designated national” or “blocked person” on the most current list published by OFAC or other similar list or is named as a “listed person” or “listed entity” on other lists made under any
Anti-Terrorism Law. 
 “Borrower” and “Borrowers” mean the entity(ies)
described in the first paragraph of this Agreement and each of their successors and permitted assigns.  
 “Borrower
Representative” means Principal Borrower, in its capacity as Borrower Representative pursuant to the provisions of Section 2.9, or any successor Borrower Representative selected by Borrowers and approved by Administrative Agent.

 “Business Day” means any day except a Saturday, Sunday or other day on which either the New York Stock Exchange is
closed, or on which commercial banks in Chicago and New York City are authorized by law to close. 
 “CERCLA” means the
Comprehensive Environmental Response, Compensation and Liability Act of 1980. 
 “Change in Control” means: 
 (a) at all times that the applicable Person is not an entity whose equity is registered with the SEC, and/or is publicly traded on and/or registered with
a public securities exchange, any of the following: (i) any change in the legal or beneficial ownership of the capital stock, partnership interests or membership interests, or in the capital structure, organizational documents or governing
documents, of the applicable Person; (ii) any pledge, assignment or hypothecation of or Lien or encumbrance on any of the legal or beneficial equity interests in the applicable Person; (iii) any change in the legal or beneficial ownership
or control of the outstanding voting equity interests of the applicable Person necessary at all times to elect a majority of the board of directors (or similar governing body) of each such Person and to direct the management policies and decisions
of such Person; (iv) the applicable Person shall cease to, directly or indirectly, own and control one hundred percent (100%) of each class of the outstanding equity interests of each Subsidiary of such Person; or (v) Principal
Borrower ceases to own, directly or indirectly, 100% of the outstanding capital stock having ordinary voting power to elect a majority of the board of directors of any of its Subsidiaries; and 
 (b) at all times that the applicable Person is an entity whose equity is registered with the SEC, and/or is publicly traded on and/or registered with a
public securities exchange, any of the following: (a) any Person or two 

  

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or more Persons acting in concert shall have acquired beneficial ownership, directly or indirectly, of, or shall have acquired by contract or otherwise, or
shall have entered into a contract or arrangement that, upon consummation, will result in its or their acquisition of or control over, voting stock of Principal Borrower (or other securities convertible into such voting stock) representing 49% or
more of the combined voting power of all voting stock of Principal Borrower or (b) Principal Borrower ceases to own, directly or indirectly, 100% of the voting stock of any of its Subsidiaries. As used herein, “beneficial ownership”
shall have the meaning provided in Rule 13d-3 of the Securities and Exchange Commission under the Securities Exchange Act of 1934, as amended. 
 “Closing Date” means the date of this Agreement. 
 “Code” means the Internal Revenue Code of
1986, as amended from time to time. 
 “Collateral” means all property, now existing or hereafter acquired, that is
mortgaged or pledged to, or purported to be subjected to a Lien in favor of, Administrative Agent, for the benefit of Administrative Agent and Lenders, pursuant to this Agreement and the Security Documents, including, without limitation, all of the
property described in Schedule 9.1 hereto. 
 “Commitment Annex” means Annex A to this
Agreement. 
 “Commitment Expiry Date” means forty-two (42) months from the earlier to occur of
(a) September 30, 2007, or (b) the last funding of any portion of the Term Loan. 
 “Compliance Certificate”
means a certificate, duly executed by a Responsible Officer of Borrower Representative, appropriately completed and substantially in the form of Exhibit B hereto. 
 “Contingent Obligation” means, with respect to any Person, any direct or indirect liability of such Person: (a) with respect to any
Debt of another Person (a “Third Party Obligation”) if the purpose or intent of such Person incurring such liability, or the effect thereof, is to provide assurance to the obligee of such Third Party Obligation that such Third Party
Obligation will be paid or discharged, or that any agreement relating thereto will be complied with, or that any holder of such Third Party Obligation will be protected, in whole or in part, against loss with respect thereto; (b) with respect
to any undrawn portion of any letter of credit issued for the account of such Person or as to which such Person is otherwise liable for the reimbursement of any drawing; (c) under any swap agreement or other derivative instrument, to the extent
not yet due and payable; (d) to make take-or-pay or similar payments if required regardless of nonperformance by any other party or parties to an agreement; or (e) for any obligations of another Person pursuant to any guaranty or pursuant
to any agreement to purchase, repurchase or otherwise acquire any obligation or any property constituting security therefor, to provide funds for the payment or discharge of such obligation or to preserve the solvency, financial condition or level
of income of another Person. The amount of any Contingent Obligation shall be equal to the amount of the obligation so guarantied or otherwise supported or, if not a fixed and determinable amount, the maximum amount so guarantied or otherwise
supported. 
 “Credit Exposure” means any period of time during which the Term Loan Commitment is outstanding or any
Obligation remains unpaid or outstanding; provided, however, that no Credit Exposure shall be deemed to exist solely due to the existence of contingent indemnification liability, absent the assertion of a claim, or the known existence of a claim
reasonably likely to be asserted, with respect thereto. 
 “Credit Party” means any guarantor under a guaranty of the
Obligations or any part thereof, any Borrower and any other Person (other than Administrative Agent, a Lender or a participant of a Lender), whether now existing or hereafter acquired or formed, that becomes obligated as a borrower, guarantor,
surety, indemnitor, pledgor, assignor or other obligor under any Financing Document; and “Credit Parties” means all such Persons, collectively. 
 “Debt” of a Person means at any date, without duplication, (a) all obligations of such Person for borrowed money, (b) all obligations of such Person evidenced by bonds, debentures, notes or
other similar instruments, (c) all obligations of such Person to pay the deferred purchase price of property or services, except trade accounts payable arising and paid on a timely basis and in the Ordinary Course of Business, (d) all
capital leases of such Person, (e) all non-contingent obligations of such Person to reimburse any bank or other Person in respect of amounts paid 

  

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under a letter of credit, banker’s acceptance or similar instrument, (f) all equity securities of such Person subject to repurchase or redemption
otherwise than at the sole option of such Person, (g) all obligations secured by a Lien on any asset of such Person, whether or not such obligation is otherwise an obligation of such Person, (h) “earnouts”, purchase price
adjustments, profit sharing arrangements, deferred purchase money amounts and similar payment obligations or continuing obligations of any nature of such Person arising out of purchase and sale contracts; (i) all Debt of others guarantied by
such Person; (j) off-balance sheet liabilities and/or Pension Plan liabilities or Multiemployer Plan liabilities of such Person; (k) obligations arising under non-compete agreements; and (l) obligations arising under bonus, deferred
compensation, incentive compensation or similar arrangements, other than those arising in the Ordinary Course of Business. Without duplication of any of the foregoing, Debt of Borrowers shall include any and all Loans. 
 “Default” means any condition or event which with the giving of notice or lapse of time or both would, unless cured or waived, become an
Event of Default. 
 “Defaulted Lender” means, so long as such failure shall remain in existence and uncured, any Lender
which shall have failed to make any Loan or other credit accommodation, disbursement, settlement or reimbursement required pursuant to the terms of any Financing Document. 
 “Deposit Account” means a “deposit account” (as defined in Article 9 of the UCC). 
 “Deposit Account Control Agreement” means an agreement, in form and substance satisfactory to Administrative Agent, among Administrative
Agent, any applicable Borrower and each bank or financial institution in which such Borrower maintains a Deposit Account pursuant to which Administrative Agent shall obtain “control” (as defined in Article 9 of the UCC) over such Deposit
Account. 
 “Dollars” or “$” means the lawful currency of the United States of America. 
 “Domestic Subsidiary” means a Subsidiary that is organized under the laws of the United States of America, one of the States,
territories, or possessions thereof, or the District of Columbia. 
 “Draw” has the meaning set forth in
Section 2.1(a). 
 “Eligible Assignee” means (i) a Lender, (ii) an Affiliate of a Lender, and (iii) an
Approved Assignee or any other Person (other than a natural person) approved by (a) Administrative Agent, and (b) unless an Event of Default has occurred and is continuing, Borrower Representative (such approval of Borrower Representative
not to be unreasonably withheld or delayed, and shall be deemed provided unless expressly withheld by Borrower Representative within five (5) Business Days of written request therefor); provided that notwithstanding the foregoing,
(x) “Eligible Assignee” shall not include Borrowers or any of Borrowers’ Affiliates or Subsidiaries and (y) no proposed assignee intending to assume any unfunded portion of the Term Loan Commitment shall be an Eligible
Assignee unless such proposed assignee either already holds a portion of such Term Loan Commitment, or has been approved as an Eligible Assignee by Administrative Agent. 
 “Environmental Laws” means any and all Laws relating to the environment or the effect of the environment on human health or to emissions, discharges or releases of pollutants, contaminants, medical
wastes, Hazardous Materials or wastes into the environment, including ambient air, surface water, ground water or land, or otherwise relating to the manufacture, processing, distribution, use, treatment, storage, disposal, transport or handling of
pollutants, contaminants, medical wastes, Hazardous Materials or wastes or the clean-up or other remediation thereof. 
 “ERISA” means the Employee Retirement Income Security Act of 1974, as the same may be amended, modified or supplemented from time to time, and any successor statute thereto, and any and all rules or regulations promulgated
from time to time thereunder. 
 “ERISA Affiliate” shall mean any person required to be aggregated with any Borrower or any
of its Subsidiaries under Section 414(b), 414(c), 414(m) or 414(o) of the Code. 
  

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 “ERISA Employee Benefit Plan” means any employee benefit plan within the meaning of
Section 3(3) (other than a Pension Plan or a Multiemployer Plan) which is maintained or otherwise contributed to by any Borrower or any Subsidiary of any Borrower or any other ERISA Affiliate. 
 “Event of Default” has the meaning set forth in Section 10.1. 
 “Excluded Property” has the meaning set forth in Schedule 9.1. 
 “Financing Documents” means this Agreement, any Notes, the Security Documents, any fee letter among Merrill Lynch and any of the
Borrowers relating to the transactions contemplated hereby, any subordination or intercreditor agreement pursuant to which any Debt and/or any Liens securing such Debt is subordinated to all or any portion of the Obligations and all other documents,
instruments and agreements related to the Obligations and heretofore executed, executed concurrently herewith or executed at any time and from time to time hereafter, as any or all of the same may be amended, supplemented, restated or otherwise
modified from time to time.  
 “Foreign Subsidiary” means any Subsidiary that is not a Domestic Subsidiary.

 “GAAP” means generally accepted accounting principles set forth from time to time in the opinions and pronouncements of
the Accounting Principles Board and the American Institute of Certified Public Accountants and statements and pronouncements of the Financial Accounting Standards Board (or agencies with similar functions of comparable stature and authority within
the United States accounting profession), which are applicable to the circumstances as of the date of determination. 
 “Governmental
Authority” means any nation or government, any state or other political subdivision thereof, and any agency, department or Person exercising executive, legislative, judicial, regulatory or administrative functions of or pertaining to
government and any corporation or other Person owned or controlled (through stock or capital ownership or otherwise) by any of the foregoing, whether domestic or foreign. 
 “Hazardous Materials” means (a) any “hazardous substance” as defined in CERCLA, (b) any “hazardous waste” as defined by the Resource Conservation and Recovery Act,
(c) asbestos, (d) polychlorinated biphenyls, (e) petroleum, its derivatives, by-products and other hydrocarbons, (f) mold, and (g) any other pollutant, medical waste, toxic, radioactive, caustic or otherwise hazardous
substance regulated under Environmental Laws. 
 “Indemnitees” has the meaning set forth in Section 12.15. 

“Intellectual Property” means, with respect to any Person, all patents, patent applications and like protections, including
improvements, divisions, continuation, renewals, reissues, extensions and continuations in part of the same, trademarks, trade names, trade styles, trade dress, service marks, logos and other business identifiers and, to the extent permitted under
applicable law, any applications therefore, whether registered or not, and the goodwill of the business of such Person connected with and symbolized thereby, copyright rights, copyright applications, copyright registrations and like protections in
each work of authorship and derivative works, whether published or unpublished, technology, know-how and processes, operating manuals, trade secrets, computer hardware and software, rights to unpatented inventions and all applications and licenses
therefor, used in or necessary for the conduct of business by such Person and all claims for damages by way of any past, present or future infringement of any of the foregoing. 
 “Interest-Only Period” means a period of six (6) months, commencing on the date of the applicable advance of the Term Loan.

 “Investissment Quebec Debt” has the meaning set forth in Section 4.6. 
 “Investment” means any investment in any Person, whether by means of acquiring (whether for cash, property, services, securities or
otherwise) or holding securities, capital contributions, loans, time deposits, advances, guaranties or otherwise. The amount of any Investment shall be the original cost of such Investment plus the cost of all additions thereto, without any
adjustments for increases or decreases in value, or write-ups, write-downs or write-offs with respect thereto. 
  

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 “IP Proceeds” has the meaning set forth in Schedule 9.1.

 “Laws” means any and all federal, state, provincial, territorial, local and foreign statutes, laws, judicial decisions,
regulations, guidances, guidelines, ordinances, rules, judgments, orders, decrees, codes, plans, injunctions, permits, concessions, grants, franchises, governmental agreements and governmental restrictions, whether now or hereafter in effect, which
are applicable to any Credit Party in any particular circumstance. “Laws” includes, without limitation, Environmental Laws. 
 “Lender” means each of (a) Merrill Lynch, in its capacity as a lender hereunder, (b) each other Person party hereto in its capacity as a lender hereunder, (c) each other Person that becomes a party hereto as
Lender pursuant to Section 12.6, and (d) the respective successors of all of the foregoing, and “Lenders” means all of the foregoing. 
 “LIBOR Rate” means, with respect to each respective individual advance made under the Term Loan, a fixed rate per annum (rounded upwards, if necessary, to the nearest 1/100 of 1%) equal to
(a) the rate of interest which is identified and normally published by Bloomberg Professional Service Page BBAM 1 as the offered rate for loans in United States dollars for the period of one (1) month under the caption British Bankers
Association LIBOR Rates as of 11:00 a.m. (London time) on the second full Business Day prior to the date such advance was made; divided by (b) the sum of one minus the daily average during the preceding
month of the aggregate maximum reserve requirement (expressed as a decimal) then imposed under Regulation D of the Board of Governors of the Federal Reserve System (or any successor thereto) for “Eurocurrency Liabilities” (as defined
therein). If Bloomberg Professional Service (or another nationally-recognized rate reporting source acceptable to Administrative Agent) no longer reports the LIBOR or Administrative Agent determines in good faith that the rate so reported no longer
accurately reflects the rate available to Administrative Agent in the London Interbank Market or if such index no longer exists or if Page BBAM 1 no longer exists or accurately reflects the rate available to Administrative Agent in the London
Interbank Market, Administrative Agent may select a comparable replacement index or replacement page, as the case may be. 
 “Lien” means, with respect to any asset, any mortgage, lien, pledge, charge, security interest or encumbrance of any kind, or any other type of preferential arrangement that has the practical effect of creating a security
interest, in respect of such asset. For the purposes of this Agreement and the other Financing Documents, any Borrower or any Subsidiary shall be deemed to own subject to a Lien any asset which it has acquired or holds subject to the interest of a
vendor or lessor under any conditional sale agreement, capital lease or other title retention agreement relating to such asset. 
 “Litigation” means any action, suit or proceeding before any court, mediator, arbitrator or Governmental Authority. 
 “Loan(s)” means the Term Loan and each and every advance under the Term Loan, as the context may require. All references herein to the “making” of a Loan or words of similar import shall mean, with respect to the
Term Loan, the making of any advance in respect of a Term Loan. 
 “Material Adverse Effect” means (subject to the
exceptions set forth in Schedule 1.1) with respect to any event, act, condition or occurrence of whatever nature (including any adverse determination in any litigation, arbitration, or governmental investigation or proceeding), whether
singly or in conjunction with any other event or events, act or acts, condition or conditions, occurrence or occurrences, whether or not related, a material adverse change in, or a material adverse effect upon, any of (i) the condition
(financial or otherwise), operations, business, properties or prospects of any of the Credit Parties, (ii) the rights and remedies of Administrative Agent or Lenders under any Financing Document, or the ability of any Credit Party to perform
any of its obligations under any Financing Document to which it is a party, (iii) the legality, validity or enforceability of any Financing Document, (iv) the existence, perfection or priority of any security interest granted in any
Financing Document, or (v) the value of any material Intellectual Property or material Collateral. 
  

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 “Material Contracts” means (a) employment agreements covering the management of any
Credit Party, (b) collective bargaining agreements or other similar labor agreements covering any employees of any Credit Party, (c) agreements for managerial, consulting or similar services to which any Credit Party is a party or by which
it is bound, (d) agreements regarding any Credit Party, its assets or operations or any investment therein to which any of its equity holders is a party or by which it is bound, (e) real estate leases, Intellectual Property licenses,
agreements providing for the sale or transfer of rights to Intellectual Property providing for ongoing royalty or similar payment to the seller or transferor, or other lease or license agreements to which any Credit Party is a party, either as
lessor or lessee, or as licensor or licensee (other than licenses arising from the purchase of “off the shelf” products), or seller/transferor or buyer/transferee, (f) customer, distribution, marketing or supply agreements to which
any Credit Party is a party, (g) partnership agreements to which any Credit Party is a general partner or joint venture agreements to which any Credit Party is a party, (h) third party billing arrangements to which any Credit Party is a
party, or (i) any other agreements or instruments to which any Credit Party is a party, and the breach, nonperformance or cancellation of which, or the failure of which to renew, could reasonably be expected to have a Material Adverse Effect,
provided that, in each case with respect to the preceding clauses (a), (c), (d), (e) and (f) such agreement or contract requires payment of more than $100,000 in any year. 
 “Maximum Lawful Rate” has the meaning set forth in Section 2.7. 
 “Merrill Lynch” means Merrill Lynch Capital, a division of Merrill Lynch Business Financial Services Inc., and its successors.

 “Multiemployer Plan” means a multiemployer plan within the meaning of Section 4001(a)(3) of ERISA. 
 “Non-Funding Lender” means a Lender that has delivered a notice to the Administrative Agent stating that such Lender shall cease making
advances in respect of the Term Loan (if any portion of the Term Loan Commitment remains unfunded and available at the applicable time) due to the non-satisfaction of one or more conditions set forth in Article 7, and specifying any such
non-satisfied conditions; provided, however, that any Lender delivering any such notice shall be a Non-Funding Lender solely over the period commencing on the Business Day following receipt by Administrative Agent of such notice, and
terminating on such date that such Lender has either revoked the effectiveness of such notice or acknowledged to Administrative Agent the satisfaction of the condition specified in such notice. 
 “Notes” shall have the meaning set forth in Section 2.3. 
 “Notice of Borrowing” means a notice of a Responsible Officer of Borrower Representative, appropriately completed and substantially in
the form of Exhibit D hereto. 
 “Obligations” means all obligations, liabilities and indebtedness (monetary
(including post-petition interest, whether or not allowed) or otherwise) of each Credit Party under this Agreement or any other Financing Document, in each case howsoever created, arising or evidenced, whether direct or indirect, absolute or
contingent, now or hereafter existing, or due or to become due. 
 “OFAC” means the U.S. Department of Treasury Office of
Foreign Assets Control. 
 “OFAC Lists” means, collectively, the Specially Designated Nationals and Blocked Persons List
maintained by OFAC pursuant to Executive Order No. 13224, 66 Fed. Reg. 49079 (Sept. 25, 2001) and/or any other list of terrorists or other restricted Persons maintained pursuant to any of the rules and regulations of OFAC or pursuant to any
other applicable Executive Orders. 
 “Ordinary Course of Business” means, in respect of any transaction involving any
Credit Party, the ordinary course of business of such Credit Party, as conducted by such Credit Party in accordance with past practices. 
 “Organizational Documents” means, with respect to any Person other than a natural person, the documents by which such Person was organized (such as a certificate of incorporation, certificate of limited 

  

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partnership or articles of organization, and including, without limitation, any certificates of designation for preferred stock or other forms of preferred
equity) and which relate to the internal governance of such Person (such as by-laws, a partnership agreement or an operating, limited liability or members agreement). 
 “Payment Account” means the account specified on the signature pages hereof into which all payments by or on behalf of each Borrower to Administrative Agent under the Financing Documents shall be
made, or such other account as Administrative Agent shall from time to time specify by notice to Borrower Representative. 
 “Payment
Notification” means a written notification substantially in the form of Exhibit E hereto. 
 “Pension
Plan” means an employee pension benefit plan (other than a Multiemployer Plan) which is covered by Title IV of ERISA or subject to the minimum funding standards under Section 412 of the Code. 
 “Permits” means all governmental licenses, authorizations, provider numbers, supplier numbers, registrations, permits, drug or device
authorizations and approvals, certificates, franchises, qualifications, accreditations, consents and approvals required under all applicable Laws and required in order to carry on its business as now conducted. 
 “Permitted Acquisitions” means the acquisition of all or substantially all of the assets of another Person, or of a business line
or a unit or division of another Person, provided that after giving effect to such acquisition, no Event of Default has occurred and is continuing or would exist after giving effect to such acquisition, there shall be no decrease in the
Borrowers’ tangible net worth after giving effect to such acquisition (as confirmed to Administrative Agent pursuant to a written certificate from a Responsible Officer of Borrowers) and the aggregate amount of such acquisitions during the term
of this Agreement (together with the aggregate amount of all acquisitions permitted under clause (h) of the definition of Permitted Investments during the term of this Agreement) shall not exceed $500,000.  
 “Permitted Affiliate” means with respect to any Person (a) any Person that directly or indirectly controls such Person, and
(b) any Person which is controlled by or is under common control with such controlling Person. As used in this definition, the term “control” of a Person means the possession, directly or indirectly, of the power to vote eighty
percent (80%) or more of any class of voting securities of such Person or to direct or cause the direction of the management or policies of a Person, whether through the ownership of voting securities, by contract or otherwise. 
 “Permitted Asset Dispositions” means the following Asset Dispositions provided that, except in the case of any Asset Disposition
described in clause (f) below, at the time of such Asset Disposition, no Default or Event of Default exists or would result from such Asset Disposition: (i) dispositions of Inventory in the Ordinary Course of Business and not pursuant to
any bulk sale, (ii) dispositions of furniture, fixtures and equipment in the Ordinary Course of Business that the applicable Borrower or Subsidiary determines in good faith is no longer used or useful in the business of such Borrower and its
Subsidiaries, (iii) the granting of non-exclusive licenses, and (iv) dispositions approved by Administrative Agent and, if the disposition pertains to Intellectual Property or real property Collateral, by Required Lenders. 
 “Permitted Contest” means, with respect to any tax obligation or other obligation allegedly or potentially owing from any Borrower to
any governmental tax authority or other third party, a contest maintained in good faith by appropriate proceedings promptly instituted and diligently conducted and with respect to which such reserve or other appropriate provision, if any, as shall
be required in conformity with GAAP shall have been made on the books and records and financial statements of the applicable Borrower(s); provided, however, that (a) compliance with the obligation that is the subject of such contest is
effectively stayed during such challenge; (b) Borrowers’ title to, and its right to use, the Collateral is not adversely affected thereby and Administrative Agent’s Lien and priority on the Collateral are not adversely affected,
altered or impaired thereby; (c) the Collateral or any part thereof or any interest therein shall not be in any danger of being sold, forfeited or lost by reason of such contest by Borrowers; (d) Borrowers have given Administrative Agent
notice of the intent to so contest the obligation and the commencement of such contest and upon request by Administrative Agent, from time to time, notice of the status of such contest by Borrowers and/or confirmation of the continuing satisfaction
of this definition; and (e) upon a final determination of such contest, Borrowers shall promptly comply with the requirements thereof. 
  

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 “Permitted Contingent Obligations” means : (a) Contingent Obligations arising in
respect of the Debt under the Financing Documents; (b) Contingent Obligations outstanding on the date of this Agreement and set forth on Schedule 5.1 (but not including any refinancings, extensions, increases or amendments to the
indebtedness underlying such Contingent Obligations other than extensions of the maturity thereof without any other change in terms); (c) Contingent Obligations incurred in the Ordinary Course of Business with respect to surety and appeal
bonds, performance bonds and other similar obligations not to exceed $25,000 in the aggregate at any time outstanding and with respect to bonds provided to utilities with respect to utility services provided to Borrowers in the Ordinary Course of
Business; and (d) other Contingent Obligations not permitted by the preceding clauses, not to exceed $25,000 in the aggregate at any time outstanding. 
 “Permitted Distributions” means the following Restricted Distributions: (a) dividends by any Subsidiary of any Borrower to such Borrower; (b) dividends solely in common stock; and
(c) repurchases of stock of former employees, directors or consultants pursuant to stock repurchase agreements so long as an Event of Default does not exist at the time of such repurchase and would not exist after giving effect to such
repurchase, provided that such repurchase does not exceed $250,000 in the aggregate per fiscal year. 
 “Permitted
Indebtedness” means: (a) Borrower’s Debt to Administrative Agent and each Lender under this Agreement and the other Financing Documents; (b) Debt incurred as a result of endorsing negotiable instruments received in the
Ordinary Course of Business; (c) purchase money Debt not to exceed $250,000 at any time (whether in the form of a loan or a lease) used solely to acquire equipment used in the Ordinary Course of Business and secured only by such equipment;
(d) Debt existing on the date of this Agreement and described on Schedule 5.1 (but not including any refinancings, extensions, increases or amendments to such Debt other than extensions of the maturity thereof without any other
change in terms); (e) trade accounts payable arising and paid on a timely basis and in the Ordinary Course of Business; (f) Debt in the form of insurance premiums financed through the applicable insurance company; and (g) Subordinated
Debt. 
 “Permitted Investments” means: (a) Investments shown on Schedule 5.5 and existing on the Closing
Date; (b) (i) cash equivalents, and (ii) any similar short term Investments permitted by Borrowers’ investment policy, as amended from time to time, provided that such investment policy (and any such amendment thereto) has been
approved in writing by Administrative Agent; (c) Investments consisting of the endorsement of negotiable instruments for deposit or collection or similar transactions in the Ordinary Course of Business; (d) Investments consisting of loans
to employees, officers or directors relating to the purchase of equity securities of Borrowers or their Subsidiaries pursuant to employee stock purchase plans or agreements approved by Borrowers’ Board of Directors (or other governing body),
but the aggregate of all such loans outstanding may not exceed $100,000 at any time; (e) Investments (including debt obligations) received in connection with the bankruptcy or reorganization of customers or suppliers and in settlement of
delinquent obligations of, and other disputes with, customers or suppliers arising in the Ordinary Course of Business; (f) Investments consisting of notes receivable of, or prepaid royalties and other credit extensions, to customers and
suppliers who are not Affiliates, in the Ordinary Course of Business; provided that this subpart (f) shall not apply to Investments of Borrowers in any Subsidiary; (g) Investments consisting of Deposit Accounts or Securities Accounts
subject to a Deposit Account Control Agreement or Securities Account Control Agreement in favor of Administrative Agent or which are otherwise permitted under Section 5.9; (h) Investments consisting of the acquisition of all or
substantially all of the capital stock of another Person or the formation of a new Subsidiary provided that after giving effect to such acquisition, no Event of Default has occurred and is continuing or would exist after giving effect to such
acquisition, there shall be no decrease in the Borrowers’ tangible net worth after giving effect to such acquisition (as confirmed to Administrative Agent pursuant to a written certificate from a Responsible Officer of Borrowers), the aggregate
amount of such acquisitions during the term of this Agreement (together with all Permitted Acquisitions during the term of this Agreement) shall not exceed $500,000 and the Borrowers shall have complied with Section 5.5(b); (i) Investments
of a Borrower’s Subsidiaries in or to other such Borrower’s Subsidiaries or such Borrower and Investments (other than investments described in clause (j) below) by a Borrower in its Subsidiaries (for the sole purpose of paying such
Subsidiary’s operating expenses) not to exceed $5,000,000 in the aggregate in any twelve-month period; (j) the use of up to $10,000,000 of the proceeds of the Term Loan to pay off the Investissment Quebec Debt; and (k) other
Investments in an amount not exceeding $50,000 in the aggregate. 
 “Permitted Liens” means: (a) deposits or pledges of
cash to secure obligations under workmen’s compensation, social security or similar laws, or under unemployment insurance (but excluding Liens arising under 

  

 9 

 
ERISA) pertaining to a Borrower’s employees, if any; (b) deposits or pledges of cash to secure bids, tenders, contracts (other than contracts for
the payment of money or the deferred purchase price of property or services), leases, statutory obligations, surety and appeal bonds and other obligations of like nature arising in the Ordinary Course of Business; (c) carrier’s,
warehousemen’s, mechanic’s, workmen’s, materialmen’s or other like Liens on Collateral, other than Intellectual Property arising in the Ordinary Course of Business with respect to obligations which are not due, or which are being
contested pursuant to a Permitted Contest; (d) Liens on Collateral, other than Intellectual Property, for taxes or other governmental charges not at the time delinquent or thereafter payable without penalty or the subject of a Permitted
Contest; (e) attachments, appeal bonds, judgments and other similar Liens on Collateral other than Intellectual Property, for sums not exceeding $25,000 in the aggregate arising in connection with court proceedings; provided, however,
that the execution or other enforcement of such Liens is effectively stayed and the claims secured thereby are the subject of a Permitted Contest; (f) Liens and encumbrances in favor of Administrative Agent under the Financing Documents;
(g) Liens on assets, other than Intellectual Property, to the extent existing on the date hereof and set forth on Schedule 5.2; and (h) any Lien on any equipment securing Debt permitted under subpart (c) of the
definition of Permitted Indebtedness provided, however, that such Lien attaches concurrently with or within twenty (20) days after the acquisition thereof. 
 “Permitted Modifications” means (a) such amendments or other modifications to a Borrower’s Organizational Documents as are required under this Agreement or by applicable Law and fully
disclosed to Administrative Agent within thirty (30) days after such amendments or modifications have become effective, (b) such amendments or modifications to a Borrower’s Organizational Documents (other than those involving a change
in the name of a Borrower or involving a reorganization of the Borrower under the laws of a different jurisdiction) that would not adversely affect the rights and interests of the Administrative Agent or Lenders and fully disclosed to Administrative
Agent within thirty (30) days after such amendments or modifications have become effective, and (c) such modifications to the name of a Borrower or involving a reorganization of the Borrower under the laws of a different jurisdiction so
long as the provisions of Section 9.2(d) are fully complied with prior to the effectiveness of such amendments or modifications. 
 “Permitted Transfers” means (a) the collective reference to one or more transfers, via a sale and not by pledge or hypothecation, which, in the aggregate during the term of this Agreement, result in a transfer of legal
or beneficial ownership or control of up to forty nine percent (49%) of the direct or indirect ownership or voting interests in the Borrowers or any guarantor of the Obligations to a Person, (i) purchasing such ownership interest in a
public offering registered with the SEC or (ii) other than a Blocked Person, that is (A) a venture capital investor so long as Borrowers have given Administrative Agent at least fifteen (15) days prior written notice of the identity
of the assignees, together with such information as Administrative Agent shall deem necessary to confirm that such assignee is not a Blocked Person or (B) at the time of such transfer, already a holder of direct or indirect ownership or voting
interests in the Borrowers, and (b) the exchange by stockholders of the Principal Borrower’s Canadian Subsidiaries of capital stock in a Canadian Subsidiary of the Principal Borrower for common stock of the Principal Borrower.
Notwithstanding the limitations set forth in the foregoing sentence (a) any holder of direct or indirect ownership or voting interests in the Borrowers which is a partnership may transfer such holder’s rights to such holder’s
constituent partners, retired partners (including spouses, ancestors, lineal descendants and siblings of such partners or spouses who acquire such interests by gift, will or intestate succession) or their respective Affiliates, (b) any holder
of direct or indirect ownership or voting interests in the Borrowers which is a limited liability company may transfer such holder’s right to such holder’s members, (c) any holder of direct or indirect ownership or voting interests in
the Borrowers which is a natural person may transfer such holder’s rights to any immediate family member or to any trust created for the benefit of such holder or his or her immediate family members, and (d) any holder of direct or
indirect ownership or voting interests in the Borrowers may transfer such holder’s rights to a Permitted Affiliate of such holder (provided that no transfer of any given interest pursuant to this subpart may be made more often than once per
twelve (12) month period), subject in each case to such transferee’s agreeing in writing to be bound by the rights and restrictions of this Agreement; and any such transfer described in the foregoing clauses (a) through (d) shall
be deemed a “Permitted Transfer” and shall not count toward the forty nine percent (49%) limitation described above. 
 “Person” means any natural person, corporation, limited liability company, professional association, limited partnership, general partnership, joint stock company, joint venture, association, company, trust, bank, trust
company, land trust, business trust or other organization, whether or not a legal entity, and any Governmental Authority. 
  

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 “Principal Borrower” means Targanta Therapeutics Corporation, a Delaware corporation.

 “Pro Rata Share” means (a) with respect to a Lender’s obligation to make advances in respect of a Term Loan and
such Lender’s right to receive payments of principal and interest with respect to the Term Loans, the Term Loan Commitment Percentage of such Lender, and (b) for all other purposes with respect to any Lender, the percentage obtained by
dividing (i) the sum of the Term Loan Commitment Amount of such Lender (or, in the event the Term Loan Commitment shall have been terminated, the then outstanding principal advances of such Lender under the Term Loan), by
(ii) the sum of the Term Loan Commitment Amount (or, in the event the Term Loan Commitment shall have been terminated, the then outstanding principal advances of such Lenders under the Term Loan) of all Lenders. 
 “Required Lenders” means Lenders holding in the aggregate sixty six percent (66%) of the Term Loan Commitment or, if the Term Loan
Commitment has been terminated, sixty six percent (66%) or more of the aggregate outstanding principal balance of the Loans, provided, however, that in addition to the Lenders required pursuant to the preceding, “Required
Lenders” shall also include each Original Lender which has neither sold, assigned nor participated any interest in its original Term Loan Committed Amount to any other Person. For purposes hereof, “Original Lender” means Merrill Lynch
Capital, Oxford Finance Corporation, and Bluecrest Capital Finance, L.P., or any Affiliate of such Original Lender to which this Agreement has been assigned. 
 “Responsible Officer” means any of the Chief Executive Officer or Chief Financial Officer of the applicable Borrower. 
 “Restricted Distribution” means as to any Person (a) any dividend or other distribution (whether in cash, securities or other property) on any equity interest in such Person (except those payable
solely in its equity interests of the same class), (b) any payment on account of (i) the purchase, redemption, retirement, defeasance, surrender, cancellation, termination or acquisition of any equity interests in such Person or any claim
respecting the purchase or sale of any equity interest in such Person (except in connection with the Warrants) or (ii) any option, warrant or other right to acquire any equity interests in such Person (excluding, however the Warrants),
(c) any management fees, salaries or other fees or compensation to any Person holding an equity interest in a Borrower or a Subsidiary of a Borrower (other than (A) payments of salaries to individuals, (B) directors fees, (C) the
issuance of stock options or restricted stock to employees and board members, (D) advances and reimbursements to employees or directors, all in the Ordinary Course of Business and consistent with past practices, and (E) payments to
consultants, who are not Affiliates, for consulting services provided to a Borrower or Subsidiary, an Affiliate of a Borrower or an Affiliate of any Subsidiary of a Borrower, (d) any lease or rental payments to an Affiliate or Subsidiary of a
Borrower, or (e) repayments of or debt service on loans or other indebtedness held by any Person holding an equity interest in a Borrower or a Subsidiary of a Borrower, an Affiliate of a Borrower or an Affiliate of any Subsidiary of a Borrower
unless permitted under and made pursuant to a Subordination Agreement applicable to such loans or other indebtedness. 
 “SEC” means the United States Securities and Exchange Commission. 
 “Securities Account” means a
“securities account” (as defined in Article 9 of the UCC), an investment account, or other account in which Investment Property or Securities are held or invested for credit to or for the benefit of any Borrower. 
 “Securities Account Control Agreement” means an agreement, in form and substance satisfactory to Administrative Agent, among
Administrative Agent, any applicable Borrower and each securities intermediary in which such Borrower maintains a Securities Account pursuant to which Administrative Agent shall obtain “control” (as defined in Article 9 of the UCC) over
such Securities Account. 
 “Security Document” means this Agreement and any other agreement, document or instrument
executed concurrently herewith or at any time hereafter pursuant to which one or more Credit Parties or any other Person either (a) guaranties payment or performance of all or any portion of the Obligations, and/or (b) provides, as
security for all or any portion of the Obligations, a Lien on any of its assets in favor of Administrative Agent for its own benefit and the benefit of the Lenders, as any or all of the same may be amended, supplemented, restated or otherwise
modified from time to time. 
  

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 “Solvent” means, with respect to any Person, that such Person (a) owns and will own
assets the fair saleable value of which are (i) greater than the total amount of its liabilities (including Contingent Obligations) required to be classified upon a balance sheet as liabilities in accordance with GAAP, and (ii) greater
than the amount that will be required to pay the probable liabilities of its then existing debts as they become absolute and matured considering all financing alternatives and potential asset sales reasonably available to it; (b) has capital
that is not unreasonably small in relation to its business as presently conducted or after giving effect to any contemplated transaction; and (c) does not intend to incur and does not believe that it will incur debts beyond its ability to pay
such debts as they become due. 
 “Subordinated Debt” means any Debt of Borrowers subject to a Subordination Agreement and
incurred with the prior written consent of Administrative Agent pursuant to the applicable Subordinated Debt Documents related thereto and provided in advance to Administrative Agent, all of which documents must be in form and substance acceptable
to Administrative Agent in its sole discretion. As of the Closing Date, there is no Subordinated Debt. 
 “Subordinated Debt
Documents” means, with respect to any Debt subject to a Subordination Agreement, any and all documents evidencing and/or securing such Debt. As of the Closing Date, there are no Subordinated Debt Documents. 
 “Subordination Agreement” means any agreement between Administrative Agent and another creditor of Borrowers, as the same may be
amended, supplemented, restated or otherwise modified from time to time in accordance with the terms thereof, pursuant to which the Debt owing from any Borrower(s) and/or the Liens securing such Debt granted by any Borrower(s) to such creditor are
subordinated in any way to the Obligations and the Liens created under the Security Documents, the terms and provisions of which such Subordination Agreements have been agreed to by and are acceptable to Administrative Agent in the exercise of its
sole discretion. 
 “Subsidiary” means, with respect to any Person, (a) any corporation of which an aggregate of more
than fifty percent (50%) of the outstanding capital stock having ordinary voting power to elect a majority of the board of directors of such corporation (irrespective of whether, at the time, capital stock of any other class or classes of such
corporation shall have or might have voting power by reason of the happening of any contingency) is at the time, directly or indirectly, owned legally or beneficially by such Person or one or more Subsidiaries of such Person, or with respect to
which any such Person has the right to vote or designate the vote of more than fifty percent (50%) of such capital stock whether by proxy, agreement, operation of law or otherwise, and (b) any partnership or limited liability company in
which such Person and/or one or more Subsidiaries of such Person shall have an interest (whether in the form of voting or participation in profits or capital contribution) of more than fifty percent (50%) or of which any such Person is a
general partner or may exercise the powers of a general partner. Unless the context otherwise requires, each reference to a Subsidiary shall be a reference to a Subsidiary of a Borrower, which, for the avoidance of doubt, shall include, but not be
limited to, Targanta Therapeutiques, Inc. and Targanta Therapeutics (Ontario), Inc. 
 “Taxes” has the meaning set forth in
Section 2.8. 
 “Term Loan” has the meaning set forth in Section 2.1(a). 
 “Term Loan Commitment” means the sum of each Lender’s Term Loan Commitment Amount, which is equal to Twenty Million and No/100
Dollars ($20,000,000.00). 
 “Term Loan Commitment Amount” means, at any time, (i) as to any Lender that is a Lender on
the Closing Date, the dollar amount equal to the dollar amount set forth opposite such Lender’s name on the Commitment Annex under the column “Term Loan Commitment Amount”, as such amount and such Lender’s Term Loan Commitment
Percentage may be adjusted from time to time by any amounts assigned (with respect to such other Lender’s portion of Term Loans outstanding) pursuant to the terms of any and all effective Assignment Agreement to which such Lender is a party and
(ii) as to any Lender that becomes a Lender after the Closing Date, the amount of the “Term Loan Commitment Amount(s)” of other Lender(s) assigned to such new Lender pursuant to the terms of the effective Assignment Agreement(s)
pursuant to which such new Lender shall become a Lender, as such amount may be adjusted from time to time by any amounts assigned pursuant to the terms of any and all effective Assignment Agreement to which such Lender is a party. 
  

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 “Term Loan Commitment Percentage” means, at any time, (i) as to any Lender that is
a Lender on the Closing Date, the percentage set forth opposite such Lender’s name on the Commitment Annex under the column “Term Loan Commitment Percentage”, as such percentage may be adjusted from time to time by any portions
thereof assigned (with respect to such other Lender’s portion of Term Loans outstanding and its commitment to make Term Loans) pursuant to the terms of any and all effective assignment agreements to which such Lender is a party, and
(ii) as to any Lender that becomes a Lender after the Closing Date, the portion of the “Term Loan Commitment Percentage(s)”of other Lender(s) assigned to such new Lender pursuant to the terms of the effective assignment agreement(s)
pursuant to which such new Lender shall become a Lender, as such percentage may be adjusted from time to time by any portions thereof assigned (with respect to any such other Lender’s portion of Term Loans outstanding and its commitment to make
Term Loans) pursuant to the terms of any and all effective assignment agreements to which such Lender is a party. 
 “Term
Note” means any Note evidencing any portion of the Term Loan. 
 “Termination Date” means the earlier to occur of
(a) the Commitment Expiry Date, or (b) any date on which Administrative Agent or Required Lenders elect to accelerate the maturity of the Loans or terminate the Term Loan Commitment pursuant to Section 10.2. 
 “UCC” means the Uniform Commercial Code of the State of Illinois or of any other state the laws of which are required to be applied in
connection with the perfection of security interests in any Collateral. 
 “United States” means the United States of
America. 
 “Warrants” means those certain warrants to purchase up to 27,566 shares of Series C-1 Preferred Stock of
Targanta Therapeutics Corporation in favor of Merrill Lynch Capital, up to 9,188 shares of Series C-1 Preferred Stock of Targanta Therapeutics Corporation in favor of Oxford Finance Corporation and up to 9,188 shares of Series C-1 Preferred Stock of
Targanta Therapeutics Corporation in favor of Bluecrest Capital Finance, L.P., each at an initial exercise price equal to $13.06 per share, subject to adjustment thereunder. 
 Section 1.2 Accounting Terms and Determinations. Accounting terms not defined in this Agreement shall be construed following GAAP, and
calculations and determinations must be made following GAAP, in each case, applied on a basis consistent with the most recent audited financial statements of Principal Borrower delivered to Administrative Agent prior to the Closing Date; provided,
however, that if at any time any change in GAAP would affect the computation of any financial ratio or financial requirement set forth in any Financing Document, and either Borrowers, the Administrative Agent or the Required Lenders shall so
request, the Administrative Agent and Borrowers shall negotiate in good faith to amend such ratio or requirement to preserve the original intent thereof in light of such change in GAAP (subject to the approval of the Required Lenders). 

Section 1.3 Other Definitional Provisions. References in this Agreement to “Articles”, “Sections”,
“Annexes”, “Exhibits” or “Schedules” shall be to Articles, Sections, Annexes, Exhibits or Schedules of or to this Agreement unless otherwise specifically provided. Any term defined herein may be used in the singular or
plural. “Include”, “includes” and “including” shall be deemed to be followed by “without limitation”. Except as otherwise specified or limited herein, references to any Person include the successors and
assigns of such Person. References “from” or “through” any date mean, unless otherwise specified, “from and including” or “through and including”, respectively. References to any statute or act shall include
all related current regulations and all amendments and any successor statutes, acts and regulations. References to any statute or act, without additional reference, shall be deemed to refer to federal statutes and acts of the United States.
References to any agreement, instrument or document shall include all schedules, exhibits, annexes and other attachments thereto. As used in this Agreement, the meaning of the term “material” or the phrase “in all material
respects” is intended to refer to an act, omission, violation or condition which reflects or could reasonably be expected to result in a Material Adverse Effect. References to capitalized terms that are not defined herein, but are defined in
the UCC, shall have the meanings given them in the UCC. All Riders attached hereto are hereby incorporated herein by this reference and made a part hereof. Headings and captions used in the Financing Documents (including the Exhibits, Schedules and
Annexes hereto and thereto) are included for convenience of reference only and shall not be given any substantive effect. 
  

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 ARTICLE 2 - LOANS 
 Section 2.1 Loans. 
 (a) Term Loans. 
 (i) Term Loan Amounts. On the terms and subject to the conditions set forth herein, each Lender severally agrees to make to Borrowers a term loan
in an original principal amount equal to such Lender’s Term Loan Commitment Percentage (collectively, the “Term Loan”). Each Lender’s obligation to fund the Term Loan shall be limited to such Lender’s Term Loan
Commitment Percentage, and no Lender shall have any obligation to fund any portion of any Term Loan required to be funded by any other Lender, but not so funded. No Borrower shall have any right to reborrow any portion of the Term Loan that is
repaid or prepaid from time to time. The Term Loan may be funded in no more than three (3) advances of no less than $2,000,000 each (each, a “Draw”), and in an aggregate amount not to exceed the Term Loan Commitment;
provided, however, that no Draws under the Term Loan may be made at any time after October 15, 2007, and any portion of the Term Loan Commitment not funded as of 5:00pm (Chicago time) on October 15, 2007 shall thereupon
automatically be terminated, and the Term Loan Commitment Amount of each Lender as of such date shall be reduced by such Lender’s Pro Rata Share of such total reduction in the Term Loan Commitment. The initial Draw made under the Term Loan
shall be in an amount of not less than $7,500,000 and shall be advanced on the Closing Date. Borrowers shall deliver to Administrative Agent a Notice of Borrowing with respect to each proposed Draw, such Notice of Borrowing to be delivered no later
than noon (Chicago time) five (5) Business Days prior to such proposed Draw. 
 (ii) Scheduled Repayments; Mandatory Prepayments;
Optional Prepayments. 
 (A) There shall become due and payable in, and Borrowers
shall repay the Term Loan through, monthly scheduled principal payments based on a thirty-six (36) month straight-line amortization schedule for each Draw, which principal payments for each Draw shall begin on the first (1st) day of the sixth full calendar month following the advance of such Draw (e.g., if a Draw is made on September 15, 2007, then principal payments for
such Draw shall begin on March 1, 2008). Notwithstanding the payment schedule set forth above, on the Termination Date, there shall become due, and Borrower shall pay, the entire outstanding principal amount of the Term Loan, together with
accrued and unpaid interest thereon. 
 (B) There shall become due and payable and Borrowers shall prepay the Term Loan in the
following amounts and at the following times: 
 (i) on the date on which any Credit Party (or Administrative Agent as loss payee or
assignee) receives any casualty proceeds in excess of $100,000 of assets upon which Administrative Agent maintained a Lien, an amount equal to one hundred percent (100%) of such proceeds (net of out-of-pocket expenses and repayment of purchase
money indebtedness permitted under clause (c) of the definition of Permitted Indebtedness with respect to the property that suffered such casualty), or such lesser portion of such proceeds as Administrative Agent shall elect to apply to the
Obligations; and 
 (ii) an amount equal to any interest that is deemed to be in excess of the Maximum Lawful Rate (as defined below) and is
required to be applied to the reduction of the principal balance of the Loans by any Lender as provided for in Section 2.7. 
 (C)
Borrowers may from time to time, with at least two (2) Business Days prior delivery to Administrative Agent of an appropriately completed Payment Notification, prepay the Term Loan in whole but not in part (other than mandatory partial
prepayments required under this Agreement); provided, however, that each such prepayment shall be accompanied by any prepayment fees and exit fees required hereunder. 
  

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 (iii) All Prepayments. Except as this Agreement may specifically provide otherwise, all
prepayments of the Term Loan shall be applied by Administrative Agent to the outstanding principal balance of the Term Loan in inverse order of maturity of the scheduled payments thereon. The payments required under Section 2.1(a)(ii)(A) shall
continue in the same amount (for so long as the Term Loan and/or (if applicable) any advance thereunder shall remain outstanding) notwithstanding any partial prepayment, whether mandatory or optional, of the Term Loan. Notwithstanding anything to
the contrary contained in the foregoing, in the event that there have been multiple Draws under the Term Loan each of which such advances has a separate amortization schedule of principal payments, each prepayment of the Term Loan shall be applied
by Administrative Agent to reduce and prepay the principal balance of the earliest-made advance then outstanding in the inverse order of maturity of the scheduled payments with respect to such advance until such earliest-made advance is paid in full
(and to the extent the total amount of any such partial prepayment shall exceed the outstanding principal balance of such earliest-made advance, the remainder of such prepayment shall be applied successively to the remaining advances under the Term
Loan in the direct order of the respective advance dates in the manner provided for in this sentence). 
 Section 2.2 Interest,
Interest Calculations and Certain Fees. 
 (a) Interest. From and following the Closing Date, the Loans and the other Obligations
shall bear interest at the sum of the Base Rate plus the applicable Base Rate Margin, subject to the provisions of Section 10.4 below regarding default rates of interest. Interest on the Loans shall be paid in arrears on the first
(1st) day of each month and on the Termination Date. Interest on all other Obligations shall be payable on demand and on the Termination Date. All interest accruing on and after the Termination Date shall be immediately due and payable as it
accrues. 
 (b) Exit Fee. Borrowers shall pay to Administrative Agent, for the benefit of all Lenders committed to make Draws under
the Term Loan , as compensation for the costs of making funds available to Borrowers under this Agreement, an exit fee (the “Exit Fee”) calculated in accordance with this subsection and upon the date or dates required under this
subsection. The Exit Fee shall be equal to four percent (4.0%) of the principal amount of the applicable Draw and shall be due at the time of the final payment of principal of such Draw (whether voluntary, involuntary or mandatory). Any
remaining unpaid amount of the Exit Fee shall be due and payable on the Termination Date. All fees payable pursuant to this paragraph shall be deemed fully accrued and earned as of the Closing Date. 
 (c) Prepayment Fee. If any advance under the Term Loan is prepaid at any time, in whole or in part, for any reason (whether by voluntary
prepayment by Borrowers, by reason of the occurrence of an Event of Default or the acceleration of the Term Loan, or otherwise), or if the Term Loan shall become accelerated and due and payable in full, or if the Lenders’ funding obligations in
respect of any unfunded portion of the Term Loan shall terminate prior to the Commitment Expiry Date, Borrowers shall pay to Administrative Agent, for the benefit of all Lenders committed to make Term Loan advances on the Closing Date, as
compensation for the costs of such Lenders making funds available to Borrowers under this Agreement, a prepayment fee (the “Prepayment Fee”) calculated in accordance with this subsection. The Prepayment Fee shall be equal an amount
determined by multiplying the amount prepaid by the following applicable percentage amount: three percent (3%) for the first year following the Closing Date, two percent (2%) for the second year following the Closing Date, one percent
(1%) for the third year following the Closing Date, and zero percent (0%) thereafter. The Prepayment Fee shall not apply to or be assessed upon any prepayment made by Borrowers if such payments were required by Administrative Agent to be made
pursuant to Section 2.1(a)(ii)(B) subpart (i) (relating to casualty proceeds), subpart (ii) (relating to payments exceeding the Maximum Lawful Rate). All fees payable pursuant to this paragraph shall be deemed fully earned and
non-refundable as of the Closing Date. 
 (d) Audit Fees. Borrowers shall pay
to Administrative Agent, for its own account and not for the benefit of any other Lenders, all reasonable fees and expenses in connection with audits and inspections of Borrowers’ books and records, audits, valuations or appraisals of the
Collateral, audits of Borrowers’ compliance with applicable Laws and such other matters as Administrative Agent shall deem appropriate, which shall be due and payable on the later of (i) the first Business Day of the month following the
date of issuance by Administrative Agent of a written request for payment thereof to Borrowers, or (ii) the tenth (10th) day following the
issuance of such notice; provided, however, that so long as no Event of Default or Default has occurred, Borrowers shall be liable for such fees and expenses for no more than two (2) such audits in any given calendar year.

  

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 (e) Wire Fees. Borrowers shall pay to Administrative Agent, for its own account and not for the
account of any other Lenders, on written demand, any and all fees, costs or expenses which Administrative Agent pays to a bank or other similar institution (including, without limitation, any fees paid by Administrative Agent to any other Lender)
arising out of or in connection with (i) the forwarding to Borrowers or any other Person on behalf of Borrowers, by Administrative Agent, of proceeds of the Loans made by any Lender to Borrowers pursuant to this Agreement, and (ii) the
depositing for collection, by Administrative Agent, of any check or item of payment received or delivered to Administrative Agent on account of Obligations. 
 (f) Reserved. 
 (g) Computation of Interest and Related Fees. All interest and fees under each
Financing Document shall be calculated on the basis of a 360-day year for the actual number of days elapsed. The date of funding of a Loan shall be included in the calculation of interest. The date of payment of a Loan shall be excluded from the
calculation of interest. If a Loan is repaid on the same day that it is made, one (1) day’s interest shall be charged. 
 (h) Automated Clearing House Payments. If Administrative Agent so elects, monthly payments of interest and amortization shall be paid to Administrative Agent by Automated Clearing House debit of immediately available funds
from the financial institution account designated by Borrower Representative in the Automated Clearing House debit authorization executed by Borrowers or Borrower Representative in connection with this Agreement, and shall be effective upon receipt.
Borrowers shall execute any and all forms and documentation necessary from time to time to effectuate such automatic debiting. In no event shall any such payments be refunded to Borrowers. 
 Section 2.3 Notes. The portion of the Loans made by each Lender shall be evidenced, if so requested by such Lender, by one or more promissory
notes, in registered form, executed by Borrowers on a joint and several basis (each, a “Note”) in an original principal amount equal to such Lender’s Term Loan Commitment. 
 Section 2.4 Reserved. 
 Section 2.5 Reserved. 
 Section 2.6 General Provisions Regarding Payment; Loan Account. 
 (a) All payments to be made by each Borrower under any Financing Document, including payments of principal and interest made hereunder and pursuant to any
other Financing Document, and all fees, expenses, indemnities and reimbursements, shall be made without set-off, recoupment or counterclaim, in lawful money of the United States and in immediately available funds. If any payment hereunder becomes
due and payable on a day other than a Business Day, such payment shall be extended to the next succeeding Business Day and, with respect to payments of principal, interest thereon shall be payable at the then applicable rate during such extension
(it being understood and agreed that, solely for purposes of calculating financial covenants and computations contained herein and determining compliance therewith, if payment is made, in full, on any such extended due date, such payment shall be
deemed to have been paid on the original due date without giving effect to any extension thereto). Any payments received in the Payment Account before noon (Chicago time) on any date shall be deemed received by Administrative Agent on such date, and
any payments received in the Payment Account after noon (Chicago time) on any date shall be deemed received by Administrative Agent on the next succeeding Business Day. Unless otherwise specified herein, the settlement of all payments and fundings
hereunder between or among the parties hereto shall be made in lawful money of the United States and in immediately available funds. 
 (b)
Administrative Agent shall endeavor to provide Borrowers with a monthly statement regarding the Loans hereunder (but neither Administrative Agent nor any Lender shall have any liability if Administrative Agent shall fail to provide any such
statement). Unless any Borrower notifies Administrative Agent of any objection to any such statement (specifically describing the basis for such objection) within ninety (90) days after the date of receipt thereof, it shall be deemed final,
binding and conclusive upon Borrowers in all respects as to all matters reflected therein, absent manifest error. 
  

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 Section 2.7 Maximum Interest. In no event shall the interest charged with respect to the
Loans or any other Obligations of any Borrower under any Financing Document exceed the maximum amount permitted under the laws of the State of Illinois or of any other applicable jurisdiction. Notwithstanding anything to the contrary herein or
elsewhere, if at any time the rate of interest payable hereunder or under any Note or other Financing Document (the “Stated Rate”) would exceed the highest rate of interest permitted under any applicable law to be charged (the
“Maximum Lawful Rate”), then for so long as the Maximum Lawful Rate would be so exceeded, the rate of interest payable shall be equal to the Maximum Lawful Rate; provided, however, that if at any time thereafter the Stated
Rate is less than the Maximum Lawful Rate, each Borrower shall, to the extent permitted by law, continue to pay interest at the Maximum Lawful Rate until such time as the total interest received is equal to the total interest which would have been
received had the Stated Rate been (but for the operation of this provision) the interest rate payable. Thereafter, the interest rate payable shall be the Stated Rate unless and until the Stated Rate again would exceed the Maximum Lawful Rate, in
which event this provision shall again apply. In no event shall the total interest received by any Lender exceed the amount which it could lawfully have received had the interest been calculated for the full term hereof at the Maximum Lawful Rate.
If, notwithstanding the prior sentence, any Lender has received interest hereunder in excess of the Maximum Lawful Rate, such excess amount shall be applied to the reduction of the principal balance of the Loans or to other amounts (other than
interest) payable hereunder, and if no such principal or other amounts are then outstanding, such excess or part thereof remaining shall be paid to Borrowers. Any such reduction in the principal balance shall be applied to the Obligations owing to
Lenders in accordance with the Pro Rate Share of each Lender. In computing interest payable with reference to the Maximum Lawful Rate applicable to any Lender, such interest shall be calculated at a daily rate equal to the Maximum Lawful Rate
divided by the number of days in the year in which such calculation is made. 
 Section 2.8 Taxes; Capital Adequacy.

 (a) All payments of principal and interest on the Loans and all other amounts payable hereunder shall be made free and clear of and
without deduction for any present or future income, excise, stamp, documentary, payroll, employment, property or franchise taxes and other taxes, fees, duties, levies, assessments, withholdings or other charges of any nature whatsoever (including
interest and penalties thereon) imposed by any taxing authority, excluding taxes imposed on or measured by Administrative Agent’s or any Lender’s net income by the jurisdictions under which Administrative Agent or such Lender is organized
or conducts business (other than solely as the result of entering into any of the Financing Documents or taking any action thereunder) (all non-excluded items being called “Taxes”). If any withholding or deduction from any payment
to be made by any Borrower hereunder is required in respect of any Taxes pursuant to any applicable Law, then Borrowers will: (i) pay directly to the relevant authority the full amount required to be so withheld or deducted; (ii) promptly
forward to Administrative Agent an official receipt or other documentation satisfactory to Administrative Agent evidencing such payment to such authority; and (iii) pay to Administrative Agent for the account of Administrative Agent and Lenders
such additional amount or amounts as is necessary to ensure that the net amount actually received by Administrative Agent and each Lender will equal the full amount Administrative Agent and such Lender would have received had no such withholding or
deduction been required. If any Taxes are directly asserted against Administrative Agent or any Lender with respect to any payment received by Administrative Agent or such Lender hereunder, Administrative Agent or such Lender may pay such Taxes and
Borrowers will promptly pay such additional amounts (including any penalty, interest or expense) as is necessary in order that the net amount received by such Person after the payment of such Taxes (including any Taxes on such additional amount)
shall equal the amount such Person would have received had such Taxes not been asserted so long as such amounts have accrued on or after the day which is two hundred seventy (270) days prior to the date on which Administrative Agent or such
Lender first made written demand therefor. 
 (b) If any Borrower fails to pay any Taxes when due to the appropriate taxing authority or
fails to remit to Administrative Agent, for the account of Administrative Agent and the respective Lenders, the required receipts or other required documentary evidence, Borrowers shall indemnify Administrative Agent and Lenders for any incremental
Taxes, interest or penalties that may become payable by Administrative Agent or any Lender as a result of any such failure. 
 (c) Each
Lender that (i) is organized under the laws of a jurisdiction other than the United States, and (ii)(A) is a party hereto on the Closing Date or (B) purports to become an assignee of an interest as a Lender under this Agreement after the
Closing Date (unless such Lender was already a Lender hereunder immediately prior to 

  

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such assignment) (each such Lender a “Foreign Lender”) shall execute and deliver to each of Borrowers and Administrative Agent one or more (as
Borrowers or Administrative Agent may reasonably request) United States Internal Revenue Service Forms W-8ECI, W-8BEN, W-8IMY (as applicable) and other applicable forms, certificates or documents prescribed by the United States Internal Revenue
Service or reasonably requested by Administrative Agent certifying as to such Lender’s entitlement to a complete exemption from withholding or deduction of Taxes. Borrowers shall not be required to pay additional amounts to any Lender pursuant
to this Section 2.8 with respect to United States withholding and income Taxes to the extent that the obligation to pay such additional amounts would not have arisen but for the failure of such Lender to comply with this paragraph other than as
a result of a change in law. 
 (d) If any Lender shall determine in its commercially reasonable judgment that the adoption or taking effect
of, or any change in, any applicable Law regarding capital adequacy, in each instance, after the Closing Date, or any change after the Closing Date in the interpretation, administration or application thereof by any Governmental Authority, central
bank or comparable agency charged with the interpretation, administration or application thereof, or the compliance by any Lender or any Person controlling such Lender with any request, guideline or directive regarding capital adequacy (whether or
not having the force of law) of any such Governmental Authority, central bank or comparable agency adopted or otherwise taking effect after the Closing Date, has or would have the effect of reducing the rate of return on such Lender’s or such
controlling Person’s capital as a consequence of such Lender’s obligations hereunder to a level below that which such Lender or such controlling Person could have achieved but for such adoption, taking effect, change, interpretation,
administration, application or compliance (taking into consideration such Lender’s or such controlling Person’s policies with respect to capital adequacy) then from time to time, upon written demand by such Lender (which demand shall be
accompanied by a statement setting forth the basis for such demand and a calculation of the amount thereof in reasonable detail, a copy of which shall be furnished to Administrative Agent), Borrowers shall promptly pay to such Lender such additional
amount as will compensate such Lender or such controlling Person for such reduction, so long as such amounts have accrued on or after the day which is two hundred seventy (270) days prior to the date on which such Lender first made demand
therefor. 
 Section 2.9 Appointment of Borrower Representative. Each Borrower hereby designates Borrower Representative as its
representative and agent on its behalf for the purposes of giving instructions with respect to and receiving the disbursement of the proceeds of the Loans, giving and receiving all other notices and consents hereunder or under any of the other
Financing Documents and taking all other actions (including in respect of compliance with covenants) on behalf of any Borrower or Borrowers under the Financing Documents. Borrower Representative hereby accepts such appointment. Notwithstanding
anything to the contrary contained in this Agreement, no Borrower other than Borrower Representative shall be entitled to take any of the foregoing actions. The proceeds of each Loan made hereunder shall be advanced to or at the direction of
Borrower Representative and if not used by Borrower Representative in its business (for the purposes provided in this Agreement) shall be deemed to be immediately advanced by Borrower Representative to the appropriate other Borrower or
Borrower’s Subsidiary hereunder as an intercompany loan (collectively, “Intercompany Loans”). Borrowers shall maintain accurate books and records with respect to all Intercompany Loans and all repayments thereof. Administrative
Agent and each Lender may regard any notice or other communication pursuant to any Financing Document from Borrower Representative as a notice or communication from all Borrowers, and may give any notice or communication required or permitted to be
given to any Borrower or all Borrowers hereunder to Borrower Representative on behalf of such Borrower or all Borrowers. Each Borrower agrees that each notice, election, representation and warranty, covenant, agreement and undertaking made on its
behalf by Borrower Representative shall be deemed for all purposes to have been made by such Borrower and shall be binding upon and enforceable against such Borrower to the same extent as if the same had been made directly by such Borrower.

 Section 2.10 Joint and Several Liability. Borrowers are defined collectively to include all Persons named as one of the
Borrowers herein; provided, however, that any references herein to “any Borrower”, “each Borrower” or similar references, shall be construed as a reference to each individual Person named as one of the Borrowers herein. Each
Person so named shall be jointly and severally liable for all of the obligations of Borrowers under this Agreement. Each Borrower, individually, expressly understands, agrees and acknowledges, that the credit facilities would not be made available
on the terms herein in the absence of the collective credit of all of the Persons named as the Borrowers herein, the joint and several liability of all such Persons, and the cross-collateralization of the collateral of all such Persons. Accordingly,
each Borrower, individually acknowledges that the benefit to each 

  

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of the Persons named as one of the Borrowers as a whole constitutes reasonably equivalent value, regardless of the amount of the credit facilities actually
borrowed by, advanced to, or the amount of collateral provided by, any individual Borrower. In addition, each entity named as one of the Borrowers herein hereby acknowledges and agrees that all of the representations, warranties, covenants,
obligations, conditions, agreements and other terms contained in this Agreement shall be applicable to and shall be binding upon and measured and enforceable individually against each Person named as one of the Borrowers herein as well as all such
Persons when taken together. By way of illustration, but without limiting the generality of the foregoing, the terms of Section 10.1 of this Agreement are to be applied to each individual Person named as one of the Borrowers herein (as well as
to all such Persons taken as a whole), such that the occurrence of any of the events described in Section 10.1 of this Agreement as to any Person named as one of the Borrowers herein shall constitute an Event of Default even if such event has
not occurred as to any other Persons named as the Borrowers or as to all such Persons taken as a whole. 
 ARTICLE 3 - REPRESENTATIONS AND
WARRANTIES 
 To induce Administrative Agent and Lenders to enter into this Agreement and to make the Loans and other credit
accommodations contemplated hereby, each Borrower hereby represents and warrants to Administrative Agent and each Lender, as of the date hereof and as of the date of each Loan, that: 
 Section 3.1 Existence and Power. Each Credit Party is an entity as specified on Schedule 3.1, is duly organized, validly
existing and in good standing under the laws of the jurisdiction specified on Schedule 3.1 and no other jurisdiction, has the same legal name as it appears in such Credit Party’s Organizational Documents and an organizational
identification number (if any), in each case as specified on Schedule 3.1, and has all powers and all Permits necessary or desirable in the operation of its business as presently conducted or as presently proposed to be conducted,
except where the failure to have such Permits could not reasonably be expected to have a Material Adverse Effect. Each Credit Party is qualified to do business as a foreign entity in each jurisdiction in which it is required to be so qualified,
which jurisdictions as of the Closing Date are specified on Schedule 3.1, except where the failure to be so qualified could not reasonably be expected to have a Material Adverse Effect. Except as set forth on Schedule
3.1, no Credit Party, over the five (5) year period preceding the Closing Date, (a) has had any name other than its current name, or (b) was incorporated or organized under the laws of any jurisdiction other than its current
jurisdiction of incorporation or organization. 
 Section 3.2 Organization and Governmental Authorization; No Contravention; Binding
Effect. The execution, delivery and performance by each Credit Party of the Financing Documents to which it is a party are within its powers, have been duly authorized by all necessary action pursuant to its Organizational Documents, require no
further action by or in respect of, or filing with, any Governmental Authority and do not violate, conflict with or cause a breach or a default under (a) any Law applicable to any Credit Party or any of the Organizational Documents of any
Credit Party, or (b) any agreement or instrument binding upon it, except for such violations, conflicts, breaches or defaults as could not, with respect to this clause (b), reasonably be expected to have a Material Adverse Effect. This
Agreement and each of the other Financing Documents to which any Credit Party is a party constitutes a valid and binding agreement or instrument of such Credit Party, enforceable against such Credit Party in accordance with its respective terms,
except as the enforceability thereof may be limited by bankruptcy, insolvency or other similar laws relating to the enforcement of creditors’ rights generally and by general equitable principles. 
 Section 3.3 Capitalization. The authorized equity securities of each of the Credit Parties as of the Closing Date, including all preemptive
or other outstanding rights, options, warrants, conversion rights or similar agreements or understandings, are as set forth on Schedule 3.3. 
 Section 3.4 Financial Information; Solvency. All information delivered to Administrative Agent and pertaining to the financial condition of any Credit Party fairly presents the financial position of such
Credit Party as of such date in conformity with GAAP (and as to unaudited financial statements, subject to normal year-end adjustments and the absence of footnote disclosures). Since June 30, 2007, there has been no material adverse change in
the business, operations, properties, prospects or condition (financial or otherwise) of any Credit Party. Each Borrower and each additional Credit Party is Solvent. 
  

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 Section 3.5 Anti-Terrorism Laws. None of the Credit Parties, their Affiliates or any of their
respective agents acting or benefiting in any capacity in connection with the transactions contemplated by this Agreement is (i) in violation of any Anti-Terrorism Law, (ii) engages in or conspires to engage in any transaction that evades
or avoids, or has the purpose of evading or avoiding, or attempts to violate, any of the prohibitions set forth in any Anti-Terrorism Law, or (iii) is a Blocked Person. No Credit Party nor, to the knowledge of any Credit Party, any of its
Affiliates or agents acting or benefiting in any capacity in connection with the transactions contemplated by this Agreement, (x) conducts any business or engages in making or receiving any contribution of funds, goods or services to or for the
benefit of any Blocked Person, or (y) deals in, or otherwise engages in any transaction relating to, any property or interest in property blocked pursuant to Executive Order No. 13224, any similar executive order or other Anti-Terrorism
Law. 
 Section 3.6 Full Disclosure. None of the written information (financial or otherwise) furnished by or on behalf of any
Credit Party to Administrative Agent or any Lender in connection with the consummation of the transactions contemplated by the Financing Documents and/or in connection with the Financing Documents after the Closing Date, contains any untrue
statement of a material fact or omits to state a material fact necessary to make the statements contained herein or therein not misleading in light of the circumstances under which such statements were made. 
 Section 3.7 Reserved. 
 Section 3.8 Taxes. Except for as set forth in Schedule 3.8, all Federal, state and local tax returns, reports and statements (including all such with respect to employee income tax withholding, social security and unemployment
taxes) required to be filed by or on behalf of each Credit Party have been filed with the appropriate Governmental Authorities in all jurisdictions in which such returns, reports and statements are required to be filed for all periods for which
returns were due and, except to the extent subject to a Permitted Contest, all taxes (including real property taxes, employee income tax withholding, social security and unemployment taxes) and other charges shown to be due and payable in respect
thereof have been timely paid prior to the date on which any fine, penalty, interest, late charge or loss may be added thereto for nonpayment thereof (and, with respect to any employee income tax withholding, social security and unemployment taxes
not yet due, adequate provision for the payment thereof has been made). Except to the extent subject to a Permitted Contest, all state and local sales and use Taxes required to be paid by each Credit Party have been paid. 
 Section 3.9 Compliance with Covenants. Each Credit Party is in full compliance with all of the terms and provisions of this Agreement and the
other Financing Document, specifically including without limitation each of the affirmative and negative covenants contained in Articles 4 and 5 below, and no Default or Event of Default has occurred and is continuing. 
 Section 3.10 Litigation. There is no litigation or governmental proceeding pending or threatened in writing against any Credit Party in which
an adverse decision could reasonably be expected to have a Material Adverse Effect or which in any manner draws into question the validity and enforceability of the Financing Documents. 
 ARTICLE 4 - AFFIRMATIVE COVENANTS 
 Each Borrower agrees that, so long as any
Credit Exposure exists: 
 Section 4.1 Financial Statements and Other Reports. Each Borrower will deliver to Administrative Agent:
(1) as soon as available, but no later than thirty (30) days after the last day of each month, a company prepared consolidated and consolidating balance sheet, cash flow and income statement covering Borrower’s consolidated and
consolidating operations during the period, prepared under GAAP, consistently applied, certified by a Responsible Officer and in a form acceptable to Administrative Agent; (2) as soon as available, but no later than one hundred twenty
(120) days after the last day of Borrower’s fiscal year, audited consolidated and consolidating financial statements prepared under GAAP, consistently applied, together with an unqualified opinion on the financial statements from an
independent certified public accounting firm acceptable to Administrative Agent in its reasonable discretion; (3) within five (5) days of delivery or filing thereof, copies of all statements, reports and notices made available to
Borrower’s security holders or to any holders of Subordinated 

  

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Debt; (4) a prompt report of any legal actions pending or threatened against any Borrower or any of its Subsidiaries that could result in damages or
costs to any Borrower or any of its Subsidiaries of One Hundred Thousand Dollars ($100,000) or more; (5) prompt written notice of an event that materially and adversely affects the value of any Intellectual Property; and (6) budgets, sales
projections, operating plans and other financial information and information, reports or statements regarding the Borrowers, their business and the Collateral as Administrative Agent may from time to time reasonably request. Notwithstanding the
foregoing, at all times that Borrower is subject to the reporting requirements under the Securities Exchange Act of 1934, (a) the filing with the SEC by the Principal Borrower of any statements, reports or notices required by clause
(3) above shall constitute notice and delivery of such statements, reports or notices to the Administrative Agent, (b) the filing with the SEC by the Principal Borrower of an 8K, 10Q or 10K setting forth information required by clauses
(4) or (5) above shall constitute notice and delivery of such information to the Administrative Agent, and (c) the filing with the SEC by the Principal Borrower of a 10Q and 10K shall be deemed to replace the requirements of clauses
(1) and (2) above, respectively. Each Borrower will, as soon as available, but no later than thirty (30) days after the last day of each month, deliver to Administrative Agent, a duly completed Compliance Certificate signed by a
Responsible Officer which shall, inter alia, set forth calculations showing compliance with the financial covenants (if any) set forth in this Agreement. Promptly upon their becoming available, Borrowers shall deliver to Administrative Agent
copies of all swap agreements or other derivative instruments to which any Borrower is a party. 
 Section 4.2 Payment and
Performance of Liabilities and Obligations. Each Borrower will (and will cause each of its Subsidiaries to): (a) pay and discharge at or prior to maturity, all of their respective obligations and liabilities, including all tax liabilities
of all kind, except for such obligations and/or liabilities (i) that may be the subject of a Permitted Contest, and (ii) the nonpayment or nondischarge of which could not reasonably be expected to have a Material Adverse Effect;
(b) maintain in accordance with GAAP, appropriate reserves for the accrual of all of their respective obligations and liabilities, including all tax liabilities of all kind; and (c) not breach or permit any Subsidiary to breach, or permit
to exist any default under, the terms of any Material Contract or any other lease, commitment, contract, instrument or obligation to which it is a party, or by which its properties or assets are bound, except for such breaches or defaults which
could not reasonably be expected to have a Material Adverse Effect. 
 Section 4.3 Maintenance of Existence; Property; Insurance.

 (a) Each Borrower will preserve, renew and keep in full force and effect and in good standing (i) their respective existence and
(ii) their respective rights, privileges and franchises necessary or desirable in the normal conduct of business. 
 (b) Subject to
Section 4.9, each Borrower will, and will cause each of its Subsidiaries to, as of the Closing Date and at all times thereafter, be the lawful owner of, have good and marketable title to and be in lawful possession of, or have valid leasehold
interests in, all properties and other assets (real or personal, tangible, intangible or mixed) purported or reported to be owned or leased (as the case may be) by such Person. Each Borrower will keep all property useful and necessary in its
business in good working order and condition, ordinary wear and tear excepted. If all or any part of the Collateral useful or necessary in its business, becomes damaged or destroyed, each Borrower will promptly and completely repair and/or restore
the affected Collateral in a good and workmanlike manner, regardless of whether Administrative Agent agrees to disburse insurance proceeds or other sums to pay costs of the work of repair or reconstruction. 
 (c) Each Borrower will, and will cause each of its Subsidiaries to, maintain (i) all insurance described on Schedule 4.3, upon the
terms and with the coverages and rights in favor of Administrative Agent and Lenders as described in Schedule 4.3, and (ii) such other insurance coverage in such amounts and with respect to such risks as Administrative Agent may
reasonably from time to time request provided, however, that, in no event shall such insurance be in amounts or with coverage less than, or with carriers with qualifications inferior to, any of the insurance or carriers in existence as of the
Closing Date (or required to be in existence after the Closing Date under a Financing Document), as evidenced by the insurance certificates attached hereto as Schedule 4.3. On or prior to the Closing Date, and at all times thereafter,
each Borrower will cause Administrative Agent, for the benefit of Lenders, to be named as an additional insured, assignee and loss payee (which shall include, as applicable, identification as mortgagee), as applicable, on each insurance policy
required to be maintained pursuant to this Section 4.3 pursuant to endorsements in form and content acceptable to Administrative Agent. All such insurance shall be provided by 

  

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insurers having an A.M. Best policyholders rating reasonably acceptable to Administrative Agent. Borrowers will deliver to Administrative Agent and the
Lenders (i) at least 60 days prior to expiration of any policy of insurance, evidence of renewal of such insurance upon the terms and conditions herein required, (ii) upon the request of any Lender through Administrative Agent from time to
time full information as to the insurance carried, (iii) within five (5) days of receipt of notice from any insurer, a copy of any notice of cancellation, nonrenewal or material change in coverage from that existing on the date of this
Agreement, and (iv) forthwith, notice of any cancellation or nonrenewal of coverage by any Borrower. In the event any Borrower (i) fails to maintain the insurance coverage required by this Agreement, or (ii) fails to provide
Administrative Agent with evidence of the insurance coverage required by this Agreement and such failure to provide evidence continues for five (5) Business Days, Administrative Agent may (but shall have no obligation to) purchase insurance at
Borrowers’ expense to protect Administrative Agent’s and each Lender’s interests in the Collateral and to protect Administrative Agent and Lenders from liability claims relating to the Borrowers’ operations, and the costs and
expenses of Administrative Agent in obtaining and paying the premiums on any such insurance shall constitute part of the Obligations for which the Borrowers are jointly and severally liable hereunder and which are secured by the Collateral. Without
limiting the generality of the foregoing, in the event that any Credit Party shall at any time receive any insurance proceeds under any property or casualty insurance maintained by any Credit Party in connection with any casualty event involving the
Collateral, Borrowers shall and shall cause each Credit Party to (regardless of any rights Borrowers may have under clause (1) of the immediately following sentence) immediately turn over and deliver to Administrative Agent any and all such
proceeds in the form received together with any necessary endorsement thereto by any and all applicable Credit Parties. 
 Section 4.4 Compliance with Laws and Contracts. Each Borrower will, and will cause each of its Subsidiaries to, comply with the requirements of all applicable Laws and all Material Contracts, except to the extent that failure to
so comply could not reasonably be expected to (a) have a Material Adverse Effect, or (b) result in any Lien upon either (i) a material portion of the assets of any such Person in favor of any Governmental Authority, or (ii) any
Intellectual Property. Schedule 4.4 sets forth a complete list of Material Contracts as of the Closing Date, and the closing on and consummation of the transactions contemplated by the Financing Documents will not give rise to a right
of termination under any such Material Contract listed on Schedule 4.4 in favor of any party (other than a Credit Party) to such Material Contract. 
 Section 4.5 Inspection of Property, Books and Records. Each Borrower will permit at the sole cost of Borrowers (subject, however, to any limitations set forth in Section 2.2(d), representatives of
Administrative Agent and of any Lender reasonable access during normal business hours to visit and inspect any of their respective properties, to examine and make abstracts or copies from any of their respective books and records, to conduct a
collateral audit and analysis of their respective operations and the Collateral, and to discuss their respective affairs, finances and accounts with their respective officers, employees and independent public accountants as often as may reasonably
be desired. In the absence of an Event of Default, Administrative Agent or any Lender exercising any rights pursuant to this Section shall give the applicable Borrower or any applicable Subsidiary commercially reasonable prior notice of such
exercise. No notice shall be required during the existence and continuance of any Event of Default or any time during which Administrative Agent reasonably believes an Event of Default exists. 
 Section 4.6 Use of Proceeds. Borrowers shall use the proceeds of the Term Loan solely for (a) the payment in full on the Closing Date of
all Debt owed by Principal Borrower, in its capacity as guarantor pursuant to that certain Guaranty dated as of December 23, 2005, pursuant to which Principal Borrower guaranteed the obligations of Targanta Therapeutics, Inc., a Subsidiary of
Principal Borrower, to Investissment Quebec (the “Investissment Quebec Debt”), and (b) for working capital needs of Borrowers and their Subsidiaries. No portion of the proceeds of the Loans will be used for family, personal,
agricultural or household use. 
 Section 4.7 Estoppel Certificates. After written request by Administrative Agent, Borrowers,
within fifteen (15) days and at their expense, will furnish Administrative Agent with a statement, duly acknowledged and certified, setting forth (a) the amount of the original principal amount of the Notes, and the unpaid principal amount
of the Notes, (b) the rate of interest of the Notes, (c) the date payments of interest and/or principal were last paid, (d) any offsets or defenses to the payment of the Obligations, and if any are alleged, the nature thereof,
(e) that the Notes and this Agreement have not been modified or if modified, giving particulars of such modification, and (f) that there has occurred and is then continuing no Default or Event of Default or if such Default or Event of
Default exists, the nature thereof, the period of time it has existed, and the action being taken to remedy such Default 

  

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or Event of Default. After written request by Administrative Agent, Borrowers, within fifteen (15) days and at their expense, will furnish
Administrative Agent with a certificate, signed by a Responsible Officer of Borrowers, updating all of the representations and warranties contained in this Agreement and the other Financing Documents and certifying that all of the representations
and warranties contained in this Agreement and the other Financing Documents, as updated pursuant to such certificate, are true, accurate and complete as of the date of such certificate. 
 Section 4.8 Notices of Certain Events. 
 (a) Borrowers will give prompt written notice to Administrative Agent (a) of any litigation or governmental proceedings pending or threatened (in writing) against Borrowers or other Credit Party which would reasonably be expected to
have a Material Adverse Effect with respect to Borrowers or any other Credit Party or which in any manner calls into question the validity or enforceability of any Financing Document, (b) upon any Borrower becoming aware of the existence of any
Default or Event of Default, (c) if any Credit Party is in breach or default under or with respect to any Material Contract, or if any Credit Party is in breach or default under or with respect to any other contract, agreement, lease or other
instrument to which it is a party or by which its property is bound or affected, which breach or default could reasonably be expected to have a Material Adverse Effect, (d) of any strikes or other labor disputes pending or, to any
Borrower’s knowledge, threatened against any Credit Party, (e) if there is any infringement or claim of infringement by any other Person with respect to any Intellectual Property rights of any Credit Party that could reasonably be expected
to have a Material Adverse Effect, or if there is any claim by any other Person that any Credit Party in the conduct of its business is infringing on the Intellectual Property Rights of others, and (f) of all returns, recoveries, disputes and
claims that involve more than $100,000. Borrowers represent and warrant that Schedule 4.8 sets forth a complete list of all matters existing as of the Closing Date for which notice could be required under this Section and all
litigation or governmental proceedings pending or threatened (in writing) against Borrowers or other Credit Party as of the Closing Date. 
 (b) Without limiting the generality of the foregoing, Borrowers will give prompt written notice to Administrative Agent (a) of the issuance of any notice, notification, demand, request for information, citation, summons, complaint or
order, filing of any complaint, assessment of any penalty or initiation or initiation or threat to initiate any investigation or review , in each such case whether by any Governmental Authority or other Person, with respect to any (i) alleged
violation by any Credit Party of any Environmental Law, (ii) alleged failure by any Credit Party to have any Permits relating to or granted under any Environmental Law required in connection with the conduct of its business or to comply with
the terms and conditions thereof, except where the failure to have such Permits relating to or granted under any Environmental Law could not reasonably be expected to have a Material Adverse Effect, (iii) any generation, treatment, storage,
recycling, transportation or disposal of any Hazardous Materials, or (iv) release of Hazardous Materials; (b) if any property now owned or leased by any Credit Party or, to the knowledge of any Borrower, any property previously owned or
leased by any Credit Party, to which any Credit Party has, directly or indirectly, transported or arranged for the transportation of any Hazardous Materials, becomes listed or, to any Borrower’s knowledge, becomes proposed for listing, on the
National Priorities List promulgated pursuant to CERCLA, or CERCLIS (as defined in CERCLA) or any similar state list or becomes the subject of Federal, state or local enforcement actions or, to the knowledge of any Borrower, other investigations
which may lead to claims against any Credit Party for clean-up costs, remedial work, damage to natural resources or personal injury claims, including, without limitation, claims under CERCLA. Borrowers represent and warrant that Schedule
4.8 sets forth a complete list of all matters existing as of the Closing Date for which notice could be required under this Section. For purposes of this Section 4.8(b), each Credit Party shall be deemed to include any business or
business entity (including a corporation) that is, in whole or in part, a predecessor of such Credit Party. 
 Section 4.9
Intellectual Property. Each Credit Party shall own, or be licensed to use or otherwise have the right to use, all Intellectual Property that is material to the condition (financial or other), business or operations of such Credit Party. All
Intellectual Property existing as of the Closing Date and registered with any United States or foreign Governmental Authority (including without limitation any and all applications for the registration of any Intellectual Property with any such
United States or foreign Governmental Authority) and all licenses under which any Borrower is the licensee of any such registered Intellectual Property (or any such application for the registration of Intellectual Property) owned by another Person
are set forth on Schedule 4.9. Such Schedule 4.9 indicates in each case whether such registered Intellectual Property (or application therefor) is owned or licensed by such Credit Party, and in the case of any such
licensed registered Intellectual Property (or application therefor), lists the name and address of the licensor and the name and date of the agreement pursuant to 

  

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which such item of Intellectual Property is licensed and whether or not such license is an exclusive license and indicates whether there are any purported
restrictions in such license on the ability to such Credit Party to grant a security interest in and/or to transfer any of its rights as a licensee under such license. Except as indicated on Schedule 4.9, the applicable Credit Party is
and all times shall be the sole and exclusive owner of the entire and unencumbered right, title and interest in and to each such registered Intellectual Property (or application therefor) purported to be owned by such Borrower, free and clear of any
Liens and/or licenses in favor of third parties or agreements or covenants not to sue such third parties for infringement. All Intellectual Property of each Credit Party is and shall be fully protected and/or duly and properly registered, filed or
issued in the appropriate office and jurisdictions for such registrations, filings or issuances, except where the failure to do so would not reasonably be expected to have a Material Adverse Effect. Borrowers shall not become a party to, nor become
bound by, any material license or other agreement with respect to which any Borrower is the licensee that prohibits or otherwise restricts such Borrower from granting a security interest in such Borrower’s interest in such license or agreement
or other property. Each Credit Party shall at all times conducts its business without infringement or claim of infringement of any Intellectual Property rights of others. Each Credit Party shall, to the extent it determines, in the exercise of its
reasonable business judgment, that it is prudent to do the following: (a) protect, defend and maintain the validity and enforceability of its Intellectual Property; (b) promptly advise Administrative Agent in writing of material
infringements of its Intellectual Property; and (c) not allow any Intellectual Property material to Borrower’s business to be abandoned, forfeited or dedicated to the public without Administrative Agent’s written consent.
Notwithstanding the foregoing, the Borrowers shall, without the consent of the Agent or any Lender, be permitted to allow to lapse the registrations or applications, as applicable, of certain Intellectual Property which is licensed by a Borrower
from Eli Lilly & Company, if such Borrower has received the prior consent from Eli Lilly & Company to the lapse of such Intellectual Property registrations or applications. 
 Section 4.10 Further Assurances. 
 (a) Each Borrower will, at its own cost and expense, cause to be promptly and duly taken, executed, acknowledged and delivered all such further acts, documents and assurances as may from time to time be necessary or as Administrative Agent
or the Required Lenders may from time to time reasonably request in order to carry out the intent and purposes of the Financing Documents and the transactions contemplated thereby. 
 (b) Upon receipt of an affidavit of an officer of Administrative Agent or a Lender as to the loss, theft, destruction or mutilation of any Note or any
other Financing Document which is not of public record, and, in the case of any such mutilation, upon surrender and cancellation of such Note or other applicable Financing Document, Borrowers will issue, in lieu thereof, a replacement Note or other
applicable Financing Document, dated the date of such lost, stolen, destroyed or mutilated Note or other Financing Document in the same principal amount thereof and otherwise of like tenor. 
 (c) Upon the request of Administrative Agent, Borrowers shall obtain a landlord’s agreement or mortgagee agreement, as applicable, from the lessor
of each leased property or mortgagee of owned property with respect to any business location where any portion of the Collateral, or the records relating to such Collateral and/or software and equipment relating to such records or Collateral, is
stored or located, which agreement or letter shall be reasonably satisfactory in form and substance to Administrative Agent. Borrowers shall timely and fully pay and perform its obligations under all leases and other agreements with respect to each
leased location where any Collateral, or any records related thereto, is or may be located. 
 (d) Before the Closing Date, and thereafter
(as and when determined by Administrative Agent in its discretion), Administrative Agent shall have the right to perform, all at Borrowers’ expense, the searches described in clauses (a), (b), (c) and (d) below against Borrowers and
any other Credit Party, the results of which are to be consistent with Borrowers’ representations and warranties under this Agreement and the satisfactory results of which shall be a condition precedent to all advances of Loan proceeds, all
issuances of Lender Letters of Credit and all undertakings in respect of Support Agreements: (a) UCC searches with the Secretary of State of each jurisdiction in which the applicable Person is organized, and, if applicable, local UCC fixture
filings searches in each jurisdiction where any real estate Collateral or fixtures Collateral is located; (b) judgment, pending litigation, federal tax lien, personal property tax lien, and corporate and partnership tax lien searches, in the
state and/or local filing offices (as applicable) of each jurisdiction where the applicable Person maintains its executive offices, a place of business, or assets and the jurisdiction in which the applicable Person is organized; (c) real
property title and lien 

  

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searches in each jurisdiction in which any real property Collateral is located; and (d) searches of applicable corporate, limited liability company,
partnership and related records to confirm the continued existence, organization and good standing of the applicable Person and the exact legal name under which such Person is organized. 
 (e) Upon the request of Administrative Agent, Borrowers shall make available to Administrative Agent, without expense to Administrative Agent, Borrowers
and their officers, employees and agents and Borrowers’ books and records, to the extent that Administrative Agent may deem them reasonably necessary to prosecute or defend any third-party suit or proceeding instituted by or against
Administrative Agent or any Lender with respect to the Financing Documents, any Collateral or relating to any Borrower. 
 Section 4.11 Power of Attorney. Each of the officers of Administrative Agent is hereby irrevocably made, constituted and appointed the true and lawful attorney for Borrowers (without requiring any of them to act as such) with
full power of substitution to do the following: (a) endorse the name of Borrowers upon any and all checks, drafts, money orders, and other instruments for the payment of money that are payable to Borrowers and constitute collections on
Borrowers’ Accounts; (b) so long as Administrative Agent has provided not less than five (5) Business Days’ prior written notice to Borrowers to perform the same and Borrowers have failed to take such action, execute in the name
of Borrowers any schedules, assignments, instruments, documents, and statements that Borrowers are obligated to give Administrative Agent under this Agreement; (c) after the occurrence and during the continuance of a Default, take any action
Borrowers are required to take under this Agreement; (d) so long as Administrative Agent has provided not less than three (3) Business Days’ prior written notice to Borrowers to perform the same and Borrowers have failed to take such
action, do such other and further acts and deeds in the name of Borrowers that Administrative Agent may deem necessary or desirable to enforce any Account or other Collateral or perfect Administrative Agent’s security interest or Lien in any
Collateral; and (e) after the occurrence and during the continuance of an Event of Default, do such other and further acts and deeds in the name of Borrowers that Administrative Agent may deem necessary or desirable to enforce its rights with
regard to any Account or other Collateral. This power of attorney shall be irrevocable and coupled with an interest. 
 Section 4.12
Post Closing Requirements. Borrowers shall complete each of the post closing obligations and/or provide to Administrative Agent each of the documents, instruments, agreements and information listed on Schedule 4.12 attached hereto
on or before the date set forth for each such item thereon, each of which shall be completed or provided in form and substance satisfactory to Administrative Agent. 
 Section 4.13 Hazardous Materials; Remediation. 
 (a) If any release or disposal of Hazardous
Materials shall occur or shall have occurred on any real property or any other assets of any Borrower or any Subsidiary or any other Credit Party, such Borrower will cause, or direct the applicable Subsidiary or Credit Party to cause, the prompt
containment and removal of such Hazardous Materials and the remediation of such real property or other assets as is necessary to comply with all Environmental Laws and to preserve the value of such real property or other assets. Without limiting the
generality of the foregoing, each Borrower shall, and shall cause each other Subsidiary and Credit Party to, materially comply with each Environmental Law requiring the performance at any real property by any Borrower or any other Subsidiary or
Credit Party of activities in response to the release or threatened release of a Hazardous Material. 
 (b) Borrowers will provide Agent
within thirty (30) days after written demand therefor with a bond, letter of credit or similar financial assurance evidencing to the reasonable satisfaction of Agent that sufficient funds are available to pay the cost of removing, treating and
disposing of any Hazardous Materials or Hazardous Materials Contamination and discharging any assessment which may be established on any property as a result thereof, such demand to be made, if at all, upon Agent’s reasonable business
determination that the failure to remove, treat or dispose of any Hazardous Materials or Hazardous Materials Contamination, or the failure to discharge any such assessment could reasonably be expected to have a Material Adverse Effect. 

Section 4.14 Updates of Representations. Borrowers shall deliver to Administrative Agent within ten (10) days of the written request
of Administrative Agent an Officer’s Certificate updating all of the representations and warranties contained in this Agreement and the other Financing Documents and certifying that all of the representations and warranties contained in this
Agreement and the other Financing Documents, as updated pursuant to such Officer’s Certificate, are true, accurate and complete as of the date of such Officer’s Certificate. 
  

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 ARTICLE 5 - NEGATIVE COVENANTS 
 Each Borrower agrees that, so long as any Credit Exposure exists: 
 Section 5.1 Debt; Contingent Obligations. No Borrower will, or will permit any Subsidiary to, directly or indirectly, create, incur, assume, guarantee or otherwise become or remain directly or indirectly
liable with respect to, any Debt, except for Permitted Indebtedness. No Borrower will, or will permit any Subsidiary to, directly or indirectly, create, assume, incur or suffer to exist any Contingent Obligations, except for Permitted Contingent
Obligations. 
 Section 5.2 Liens. No Borrower will, or will permit any Subsidiary to, directly or indirectly, create, assume or
suffer to exist any Lien on any asset now owned or hereafter acquired by it, except for Permitted Liens, or enter into any agreement, document, instrument or other arrangement (except with or in favor of Administrative Agent or Lenders) with any
Person which directly or indirectly prohibits or has the effect of prohibiting any Borrower or any Subsidiary of any Borrower from assigning, mortgaging, pledging, granting a security interest in or upon, or encumbering any intellectual property of
any Borrower or any Subsidiary of any Borrower, except as is otherwise permitted in Section 5.4 hereof and the definition of “Permitted Lien” herein. 
 Section 5.3 Restricted Distributions. No Borrower will, or will permit any Subsidiary to, directly or indirectly, declare, order, pay, make or set apart any sum for any Restricted Distribution, except for
Permitted Distributions. 
 Section 5.4 Consolidations, Mergers and Sales of Assets; Change in Control. No Borrower will, or will
permit any Subsidiary to, directly or indirectly (a) consolidate or merge or amalgamate with or into any other Person, or (b) consummate any Asset Dispositions other than Permitted Asset Dispositions. No Borrower will suffer or permit to
occur any Change in Control with respect to itself, any Subsidiary or any guarantor of the Obligations other than Permitted Transfers with respect to such Persons. 
 Section 5.5 Purchase of Assets, Investments; New Subsidiaries. 
 (a) No Borrower will, or will
permit any Subsidiary to, directly or indirectly, without the prior written consent of Administrative Agent, (a) acquire or enter into any agreement to acquire any assets other than in the Ordinary Course of Business or Permitted Acquisitions;
(b) engage or enter into any agreement to engage in any joint venture or partnership with any other Person; or (c) form, acquire or own or enter into any agreement to form, acquire or own any Investment in any Person, including any new
Subsidiary, other than pursuant to Permitted Investments or Permitted Acquisitions. 
 (b) Upon the formation or acquisition of a new
Subsidiary as part of a Permitted Investment, Borrowers shall (i) pledge, have pledged or cause or have caused to be pledged to Administrative Agent pursuant to a pledge agreement in form and substance satisfactory to Administrative Agent,
(A) all of the outstanding equity interests of each new Subsidiary that is a Domestic Subsidiary owned directly or indirectly by any Borrower, and (B) 65% of the outstanding equity interests of each new Subsidiary that is a Foreign
Subsidiary owned directly by any Borrower or by any Domestic Subsidiary of any Borrower, in each case, along with undated stock or equivalent powers for such equity interests, executed in blank; (ii) unless Administrative Agent shall agree
otherwise in writing, cause the new Subsidiary to take such other actions (including entering into or joining any Security Documents) as are necessary or advisable in the reasonable opinion of the Administrative Agent in order to grant the
Administrative Agent, acting on behalf of the Lenders, a first priority Lien to secure the Obligations of all Credit Parties on all real and personal property and leasehold estates of such Subsidiary in existence as of such date and in all after
acquired property; (iii) unless Administrative Agent shall agree otherwise in writing, cause such new Subsidiary to either (at the election of Administrative Agent) become a Borrower hereunder with joint and several liability for all
obligations of Borrowers hereunder and under the other Financing Documents pursuant to a joinder agreement or other similar agreement in form and substance satisfactory to Administrative Agent or to become a 

  

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guarantor of the Obligations pursuant to a guaranty and suretyship agreement in form and substance satisfactory to Administrative Agent; and (iv) cause
the new Subsidiary to deliver certified copies of such Subsidiary’s certificate or articles of incorporation, together with good standing certificates, by-laws (or other operating agreement or governing documents), resolutions of the Board of
Directors or other governing body, approving and authorizing the execution and delivery of the Security Documents, incumbency certificates and to execute and/or deliver such other documents and legal opinions or to take such other actions as may be
requested by the Administrative Agent, in each case, in form and substance satisfactory to the Administrative Agent. 
 Section 5.6
Transactions with Affiliates. Except as otherwise disclosed on Schedule 5.6, and except for transactions (a) between Borrowers and their Subsidiaries, as otherwise permitted herein, and (b) that are disclosed to
Administrative Agent in advance of being entered into and which contain terms that are no less favorable to the applicable Borrower or any Subsidiary, as the case may be, than those which might be obtained from a third party not an Affiliate of any
Credit Party, no Borrower will, or will permit any Subsidiary to, directly or indirectly, enter into or permit to exist any transaction (including the purchase, sale, lease or exchange of any property or the rendering of any service) with any
Affiliate of any Borrower. 
 Section 5.7 Modification of Organizational Documents. No Borrower will, or will permit any
Subsidiary to, directly or indirectly, amend or otherwise modify any Organizational Documents of such Person, except for Permitted Modifications. 
 Section 5.8 Conduct of Business. No Borrower will, or will permit any Subsidiary to, directly or indirectly, engage in any line of business other than those businesses engaged in on the Closing Date and described on
Schedule 5.8 and businesses reasonably related thereto. 
 Section 5.9 Deposit Accounts and Securities Accounts. No
Borrower will, or will permit any Subsidiary to, directly or indirectly, establish any new Deposit Account or Securities Account without prior written notice to Administrative Agent and unless Administrative Agent, such Borrower or such Subsidiary
and the bank, financial institution or securities intermediary at which the account is to be opened enter into a Deposit Account Control Agreement or Securities Account Control Agreement prior to or concurrently with the establishment of such
Deposit Account or Securities Account. Borrowers represent and warrant that Schedule 5.9 lists all of the Deposit Accounts and Securities Accounts of each Borrower as of the Closing Date. The provisions of this Section requiring
Deposit Account Control Agreements shall not apply to Deposit Accounts exclusively used for payroll, payroll taxes and other employee wage and benefit payments to or for the benefit of Borrowers’ employees and identified to Administrative Agent
by Borrowers as such. 
 Section 5.10 Payments and Modifications of Subordinated Debt. No Borrower will, or will permit any
Subsidiary to, directly or indirectly, (a) declare, pay, make or set aside any amount for payment in respect of Subordinated Debt unless permitted pursuant to the applicable Subordination Agreement or (b) amend or otherwise modify the
terms of any Subordinated Debt if the effect of such amendment or modification is to (i) increase the interest rate or fees on, or change the manner or timing of payment of, such Subordinated Debt; (ii) change the dates upon which payments
of principal or interest are due on, or the principal amount of, such Subordinated Debt; (iii) change any event of default or add or make more restrictive any covenant with respect to such Subordinated Debt; (iv) change the prepayment
provisions of such Subordinated Debt or any of the defined terms related thereto; (v) change the subordination provisions thereof (or the subordination terms of any guarantee thereof); (vi) change or amend any other term if such change or
amendment would materially increase the obligations of the obligor or confer additional material rights on the holder of such Subordinated Debt in a manner adverse to any Borrower, any Subsidiaries, Administrative Agent or Lenders; or
(viii) otherwise conflict with the terms of or be prohibited under the terms of any Subordination Agreement applicable thereto. Each Borrower shall, prior to entering into any such amendment or modification, deliver to Administrative Agent
reasonably in advance of the execution thereof, any final or execution form copy thereof and, if approval of Required Lenders is required by the terms of this Agreement prior to the taking of any such action, such Borrower agrees not to take, nor
permit any of its Subsidiaries to take, any such action with respect to any such items without obtaining such approval from Required Lenders. 
 Section 5.11 Compliance with Anti-Terrorism Laws. Administrative Agent hereby notifies Borrowers that pursuant to the requirements of Anti-Terrorism Laws, and Administrative Agent’s policies and practices, Administrative
Agent is required to obtain, verify and record certain information and documentation that 

  

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identifies Borrowers and its principals, which information includes the name and address of each Borrower and its principals and such other information that
will allow Administrative Agent to identify such party in accordance with Anti-Terrorism Laws. No Borrower will, or will permit any Subsidiary to, directly or indirectly, knowingly enter into any Material Contracts with any Blocked Person or any
Person listed on the OFAC Lists. Each Borrower shall immediately notify Administrative Agent if such Borrower has knowledge that any Borrower or any additional Credit Party becomes a Blocked Person or becomes listed on the OFAC Lists or (a) is
convicted on, (b) pleads nolo contendere to, (c) is indicted on, or (d) is arraigned and held over on charges involving money laundering or predicate crimes to money laundering. No Borrower will, or will permit any Subsidiary
to, directly or indirectly, (i) conduct any business or engage in any transaction or dealing with any Blocked Person, including, without limitation, the making or receiving of any contribution of funds, goods or services to or for the benefit
of any Blocked Person, (ii) deal in, or otherwise engage in any transaction relating to, any property or interests in property blocked pursuant to Executive Order No. 13224, any similar executive order or other Anti-Terrorism Law, or
(iii) engage in or conspire to engage in any transaction that evades or avoids, or has the purpose of evading or avoiding, or attempts to violate, any of the prohibitions set forth in Executive Order No. 13224 or other Anti-Terrorism Law.

 Section 5.12 Regulated Entities and Activities; Pensions. No Borrower will, or will permit any of its Subsidiaries (or, in the
case of clauses (c), (d), (e) or (f), any ERISA Affiliate) to, (a) become an “investment company” or a company “controlled” by an “investment company” or a “subsidiary” of an “investment
company,” all within the meaning of the Investment Company Act of 1940; (b) undertake as one of its important activities extending credit to purchase or carry margin stock (as defined in Regulation U of the Board of Governors of the
Federal Reserve System) or use any of the proceeds of any Loan directly or indirectly for the purchase of purchasing or carrying, or for the purpose of reducing or retiring any indebtedness which was originally used to purchase or carry, any margin
stock; (c) maintain or contribute to or become obligated to maintain or contribute to any Pension Plan or any Multiemployer Plan or incur any liability under Title IV of ERISA; (d) fail to meet the applicable minimum funding requirements
of ERISA with respect to any ERISA Employee Benefit Plan (to the extent any such minimum funding requirements exist with respect to any such ERISA Employee Benefit Plan), or permit a “reportable event”, as defined in Section 4043(c)
of ERISA (other than an event for which the notice requirement is waived), or a non-exempt prohibited transaction, as described in Section 406 of ERISA, to occur with respect to any Pension Plan, or make any amendment to any ERISA Employee
Benefit Plan which will result or could reasonably be expected to result in the imposition of a Lien on any property or assets of any Borrower or any such Subsidiary (or ERISA Affiliate) or the requirement that any Borrower or any such Subsidiary
(or ERISA Affiliate) post a bond or provide other security under ERISA or the Code; (e) withdraw or permit any such Subsidiary (or ERISA Affiliate) to withdraw from participation in, permit partial or complete termination of, or permit the
occurrence of any other event with respect to, any present Pension Plan that could reasonably be expected to result in any liability of any Borrower to the Pension Benefit Guaranty Corporation or its successors or any other governmental agency,
(f) fail to pay (or cause its Subsidiaries to pay) all amounts and make all contributions necessary to fund all present Pension Plans in accordance with their terms, or fail to fund or make any and all contributions to any “401(k)”,
“profit sharing” or similar defined contribution plan except to the extent that failure to so fund or make contributions to any such “401(k)”, “profit sharing” or similar defined contribution plan would not reasonably
be expected to have a Material Adverse Effect, or (f) fail to comply with the Federal Fair Labor Standards Act. 
 Section 5.13
Margin Regulations. No Borrower will, or will permit any Subsidiary to, use any of the proceeds from the Loans, directly or indirectly, for the purpose of purchasing or carrying any “margin stock” (as defined in Regulation U of the
Federal Reserve Board), for the purpose of reducing or retiring any indebtedness which was originally incurred to purchase or carry any “margin stock” or for any other purpose which might cause any of the Loans to be considered a
“purpose credit” within the meaning of Regulation T, U or X of the Federal Reserve Board. 
 Section 5.14 Canadian
Operations. No Borrower will cause or permit any Accounts owing from account debtors located outside of Canada to be owed to or collected by any Subsidiary. 
  

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 ARTICLE 6 - [ RESERVED] 
 ARTICLE 7 - CONDITIONS 
 Section 7.1 Conditions to Closing. The
obligation of each Lender to make the initial Loans, shall be subject to the receipt by Administrative Agent of each agreement, document and instrument set forth on the closing checklist prepared by Administrative Agent or its counsel, each in form
and substance satisfactory to Administrative Agent and Lenders and their respective counsel, and such other closing deliverables reasonably requested by Administrative Agent and Lenders, and to the satisfaction of the following conditions precedent,
each to the satisfaction of Administrative Agent and Lenders and their respective counsel in their sole discretion: (a) the payment of all fees, expenses and other amounts due and payable under each Financing Document; (b) the absence,
since March 31, 2007, of any material adverse change in any aspect of the business, operations, properties, prospects or condition (financial or otherwise) of any Credit Party or any seller of any assets or business to be purchased by any
Borrower contemporaneous with the Closing Date, or any event or condition which could reasonably be expected to result in such a material adverse change; and (c) the receipt by Administrative Agent of such other documents, instruments and/or
agreements as Administrative Agent may reasonably request. 
 Section 7.2 Conditions to Each Loan. In addition to the conditions
set forth in Section 7.1, the obligation of the Lenders to make an advance in respect of any Loan, including on the Closing Date, is subject to the satisfaction of the following additional conditions, compliance with which shall be determined
by Administrative Agent: (a) the fact that, immediately before and after such advance, no Default or Event of Default shall have occurred and be continuing; (b) the fact that the representations and warranties of each Credit Party
contained in the Financing Documents shall be true, correct and complete on and as of the date of such advance, except to the extent that any such representation or warranty relates to an earlier date in which case such representation or warranty
shall be true and correct as of such earlier date; and (c) the fact that no adverse change in the condition (financial or otherwise), properties, business, prospects, or operations of Borrowers or any other Credit Party shall have occurred and
be continuing with respect to Borrowers or any Credit Party since the date of this Agreement. Each giving of a Notice of LC Credit Event hereunder, each giving of a Notice of Borrowing hereunder and each acceptance by any Borrower of the proceeds of
any Loan made hereunder shall be deemed to be (y) a representation and warranty by each Borrower on the date of such notice or acceptance as to the facts specified in this Section, and (z) a restatement by each Borrower that each and every
one of the representations made by it in any of the Financing Documents is true and correct in all material respects (except to the extent that such representations and warranties expressly relate solely to an earlier date). 
 ARTICLE 8 - [RESERVED] 
 ARTICLE 9 -
SECURITY AGREEMENT 
 Section 9.1 Generally. As security for the payment and performance of the Obligations, and without
limiting any other grant of a Lien and security interest in any Security Document, Borrowers hereby assign and grant to Administrative Agent, for the benefit of Lenders and Administrative Agent, a continuing first priority Lien on and security
interest in, upon, and to the personal property set forth on Schedule 9.1 attached hereto and made a part hereof. 
 Section 9.2 Representations and Warranties and Covenants Relating to Collateral. 
 (a) Borrowers shall not, and shall
not permit any Credit Party to, take any of the following actions or make any of the following changes unless Borrowers have given at least thirty (30) days prior written notice to Administrative Agent of Borrowers’ intention to take any
such action (which such written notice shall include an updated version of any Schedule impacted by such change) and have executed any and all documents, instruments and agreements and taken any other actions which Administrative Agent may request
after receiving such written notice in order to protect and preserve the Liens, rights and remedies of Administrative Agent with respect to the Collateral: (i) change the legal name or organizational identification number of any Borrower as it
appears in official filings in the jurisdiction of its organization, (ii) change the jurisdiction of incorporation or formation of any Borrower or Credit Party or allow any Borrower or Credit Party to designate any jurisdiction as an additional
jurisdiction of incorporation for such Borrower or Credit Party, or change the type of entity that it is, or (iii) change its chief executive office, principal place of business, or the location of its records concerning the Collateral or move
any Collateral to or place any Collateral on any location that is not then listed on the Schedules and/or establish any business location at any location that is not then listed on the Schedules. 
  

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 (b) Borrowers shall not adjust, settle or compromise the amount or payment of any Account, or release
wholly or partly any Account Debtor, or allow any credit or discount thereon (other than adjustments, settlements, compromises, credits and discounts in the Ordinary Course of Business, made while no Default or Event of Default exists and in amounts
which are not material with respect to the Account) without the prior written consent of Administrative Agent. Without limiting the generality of this Agreement or any other provisions of any of the Financing Documents relating to the rights of
Administrative Agent after the occurrence and during the continuance of an Event of Default, Administrative Agent shall have the right at any time after the occurrence and during the continuance of an Event of Default to: (i) exercise the
rights of Borrowers with respect to the obligation of any Account Debtor to make payment or otherwise render performance to Borrowers and with respect to any property that secures the obligations of any Account Debtor or any other Person obligated
on the Collateral, and (ii) adjust, settle or compromise the amount or payment of such Accounts. 
 (c)(i) Borrowers shall deliver to
Administrative Agent all Tangible Chattel Paper and all Instruments and Documents owned by any Borrower and constituting part of the Collateral duly endorsed and accompanied by duly executed instruments of transfer or assignment, all in form and
substance satisfactory to Administrative Agent. Borrowers shall provide Administrative Agent with “control” (as defined in Article 9 of the UCC) of all Electronic Chattel Paper owned by any Borrower and constituting part of the Collateral
by having Administrative Agent identified as the assignee on the records pertaining to the single authoritative copy thereof and otherwise complying with the applicable elements of control set forth in the UCC. Borrowers also shall deliver to
Administrative Agent all security agreements securing any such Chattel Paper and securing any such Instruments. Borrowers will mark conspicuously all such Chattel Paper and all such Instruments and Documents with a legend, in form and substance
satisfactory to Administrative Agent, indicating that such Chattel Paper and such Instruments and Documents are subject to the security interests and Liens in favor of Administrative Agent created pursuant to this Agreement and the Security
Documents. Borrowers shall comply with all the provisions of Section 5.9 with respect to the Deposit Accounts and Securities Accounts of Borrowers. 
 (ii) Borrowers shall deliver to Administrative Agent all letters of credit on which any Borrower is the beneficiary and which give rise to Letter-of-Credit Rights owned by such Borrower which constitute part of the
Collateral in each case duly endorsed and accompanied by duly executed instruments of transfer or assignment, all in form and substance satisfactory to Administrative Agent. Borrowers shall take any and all actions as may be necessary or desirable,
or that Administrative Agent may request, from time to time, to cause Administrative Agent to obtain exclusive “control” (as defined in Article 9 of the UCC) of any such Letter-of-Credit Rights in a manner acceptable to Administrative
Agent. 
 (iii) Borrowers shall promptly advise Administrative Agent upon any Borrower becoming aware that it has any interests in any
Commercial Tort Claim that constitutes part of the Collateral, which such notice shall include descriptions of the events and circumstances giving rise to such Commercial Tort Claim and the dates such events and circumstances occurred, the potential
defendants with respect such Commercial Tort Claim and any court proceedings that have been instituted with respect to such Commercial Tort Claim, and Borrowers shall, with respect to any such Commercial Tort Claim, execute and deliver to
Administrative Agent such documents as Administrative Agent shall request to perfect, preserve or protect the Liens, rights and remedies of Administrative Agent with respect to any such Commercial Tort Claim. 
 (iv) Except for Accounts and Inventory in an aggregate amount of $25,000, no Accounts or Inventory or other Collateral shall at any time be in the
possession or control of any warehouse, consignee, bailee or any of Borrowers’ agents or processors without prior written notice to Administrative Agent and the receipt by Administrative Agent, if Administrative Agent has so requested, of
warehouse receipts, consignment agreements or bailee lien waivers (as applicable) satisfactory to Administrative Agent prior to the commencement of such possession or control. Borrowers have notified Administrative Agent that Inventory is currently
located at the locations set forth on Schedule 9.2. Borrowers shall, upon the request of Administrative Agent, notify any such warehouse, consignee, bailee, agent or processor of the security interests and Liens in favor of
Administrative Agent created pursuant to this Agreement and the Security Documents, instruct such Person to hold all such Collateral for Administrative Agent’s account subject to Administrative Agent’s instructions and shall obtain an
acknowledgement from such Person that such Person holds the Collateral for Administrative Agent’s benefit. 
  

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 (v) Upon request of Administrative Agent, Borrowers shall promptly deliver to Administrative Agent any
and all certificates of title, applications for title or similar evidence of ownership of all such tangible Personal Property and shall cause Administrative Agent to be named as lienholder on any such certificate of title or other evidence of
ownership. Borrowers shall not permit any such tangible Personal Property to become Fixtures to real estate unless such real estate is subject to a Lien in favor of Administrative Agent. 
 (vi) Each Borrower hereby authorizes Administrative Agent to file without the signature of such Borrower one or more UCC financing statements relating to
liens on personal property relating to all or any part of the Collateral, which financing statements may list Administrative Agent as the “secured party” and such Borrower as the “debtor” and which describe and indicate the
collateral covered thereby as all or any part of the Collateral under the Financing Documents (including an indication of the collateral covered by any such financing statement as “all assets” of such Borrower now owned or hereafter
acquired, excluding only the Excluded Property, in such jurisdictions as Administrative Agent from time to time determines are appropriate, and to file without the signature of such Borrower any continuations of or corrective amendments to any such
financing statements, in any such case in order for Administrative Agent to perfect, preserve or protect the Liens, rights and remedies of Administrative Agent with respect to the Collateral. 
 (vii) Borrowers shall furnish to Administrative Agent from time to time any statements and schedules further identifying or describing the Collateral and
any other information, reports or evidence concerning the Collateral as Administrative Agent may reasonably request from time to time. 
 (viii) Borrowers hereby acknowledge and agree that, at all times during which any of the Lenders have any obligations or commitments to make loans or extensions of credit under this Agreement and/or any of the Obligations (other than
contingent indemnification obligations with respect to matters not yet known to Administrative Agent) are not yet paid in full, then, as between Borrowers on the one hand and Administrative Agent and Lenders on the other hand, any Lender (and/or any
Affiliate of any Lender) that has control over and a Lien on any Deposit Account or Security Account of any Borrower to secure any indebtedness, liabilities or obligations other than the Obligations under the Financing Documents shall be deemed to
hold such Lien and to have control over any such Deposit Accounts or Security Accounts both for its own benefit to secure such other indebtedness, liabilities and obligations and as agent for perfection for the benefit of the Administrative Agent
and the Lenders to secure the Obligations under the Financing Documents (and to the extent such a dual Lien in any such Deposit Account or Securities Account has not yet been granted to any such Lender (or Affiliate of Lender), Borrowers hereby make
such grant), all subject, as among the Lenders and Administrative Agent but without creating any third party beneficiary rights in Borrowers to any additional agreement among Lenders and Administrative Agent (including any such agreement in Article
11 below) regarding their respective rights and remedies with respect to such Deposit Accounts and Securities Accounts. 
 Section 9.3 UCC Remedies. 
 (a) Upon the occurrence of and during the continuance of an Event of Default under this
Agreement or the other Financing Documents, Required Lenders may direct Administrative Agent to commence the exercise of rights and remedies against Borrowers and the Collateral for its benefit and for the benefit of the Lenders. Upon (but not
before) receipt by Administrative Agent of such a direction from Required Lenders, Administrative Agent shall so commence such exercise of rights and remedies, and Administrative Agent (without the need for further instructions or direction or
consent of Required Lenders), in addition to all other rights, options, and remedies granted to Administrative Agent under this Agreement or at law or in equity, may exercise, either directly or through one or more assignees or designees, all rights
and remedies granted to it under all Financing Documents and under the UCC in effect in the applicable jurisdiction(s) and under any other applicable law; including, without limitation: 
 (i) The right to take possession of, send notices regarding, and collect directly the Collateral, with or without judicial process; 
 (ii) The right to (by its own means or with judicial assistance) enter any of Borrowers’ premises and take possession of the Collateral, or render it
unusable, or to render it usable or saleable, or dispose of the Collateral on such premises in compliance with subsection (iii) below and to take possession of Borrowers’ 

  

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original books and records, to obtain access to Borrowers’ data processing equipment, computer hardware and software relating to the Collateral and to
use all of the foregoing and the information contained therein in any manner Administrative Agent deems appropriate, without any liability for rent, storage, utilities, or other sums, and Borrowers shall not resist or interfere with such action (if
Borrowers’ books and records are prepared or maintained by an accounting service, contractor or other third party agent, Borrowers hereby irrevocably authorize such service, contractor or other agent, upon notice by Administrative Agent to such
Person that an Event of Default has occurred and is continuing, to deliver to Administrative Agent or its designees such books and records, and to follow Administrative Agent’s instructions with respect to further services to be rendered);

 (iii) The right to require Borrowers at Borrowers’ expense to assemble all or any part of the Collateral and make it available to
Administrative Agent at any place designated by Administrative Agent; 
 (iv) The right to notify postal authorities to change the address
for delivery of Borrowers’ mail to an address designated by Administrative Agent and to receive and open all mail addressed to any Borrower and further to dispose of all mail pertaining in any way to the Collateral; and 
 (v) The right to enforce Borrowers’ rights against Account Debtors and other obligors, including, without limitation, (i) the right to collect
Accounts directly in Administrative Agent’s own name (as agent for Lenders) and to charge the collection costs and expenses, including attorneys’ fees, to Borrowers, and (ii) the right, in the name of Administrative Agent or any
designee of Administrative Agent or Borrowers, to verify the validity, amount or any other matter relating to any Accounts by mail, telephone, telegraph or otherwise, including, without limitation, verification of Borrowers’ compliance with
applicable Laws. Borrowers shall cooperate fully with Administrative Agent in an effort to facilitate and promptly conclude such verification process. Such verification may include contacts between Administrative Agent and applicable federal, state
and local regulatory authorities having jurisdiction over the Borrowers’ affairs, all of which contacts Borrowers hereby irrevocably authorize. 
 (b) Each Borrower agrees that a notice received by it at least ten (10) days before the time of any intended public sale, or the time after which any private sale or other disposition of the Collateral is to be
made, shall be deemed to be reasonable notice of such sale or other disposition. If permitted by applicable law, any perishable Collateral which threatens to speedily decline in value or which is sold on a recognized market may be sold immediately
by Administrative Agent without prior notice to Borrowers. At any sale or disposition of Collateral, Administrative Agent may (to the extent permitted by applicable law) purchase all or any part of the Collateral, free from any right of redemption
by Borrowers, which right is hereby waived and released. Each Borrower covenants and agrees not to interfere with or impose any obstacle to Administrative Agent’s exercise of its rights and remedies with respect to the Collateral.
Administrative Agent shall have no obligation to clean-up or otherwise prepare the Collateral for sale. Administrative Agent may comply with any applicable state or federal law requirements in connection with a disposition of the Collateral and
compliance will not be considered to adversely affect the commercial reasonableness of any sale of the Collateral. Administrative Agent may sell the Collateral without giving any warranties as to the Collateral. Administrative Agent may specifically
disclaim any warranties of title or the like. This procedure will not be considered to adversely affect the commercial reasonableness of any sale of the Collateral. If Administrative Agent sells any of the Collateral upon credit, Borrowers will be
credited only with payments actually made by the purchaser, received by Administrative Agent and applied to the indebtedness of the purchaser. In the event the purchaser fails to pay for the Collateral, Administrative Agent may resell the Collateral
and Borrowers shall be credited with the proceeds of the sale. Borrowers shall remain liable for any deficiency if the proceeds of any sale or disposition of the Collateral are insufficient to pay all Obligations. 
 (c) Without restricting the generality of the foregoing and for the purposes aforesaid, each Borrower hereby appoints and constitutes Administrative
Agent its lawful attorney-in-fact with full power of substitution in the Collateral, upon the occurrence and during the continuance of a Default, to use unadvanced funds remaining under this Agreement or which may be reserved, escrowed or set aside
for any purposes hereunder at any time, or to advance funds in excess of the face amount of the Notes, to pay, settle or compromise all existing bills and claims, which may be Liens or security interests, or to avoid such bills and claims becoming
Liens against the Collateral; to execute all applications and certificates in the name of such Borrower and to prosecute and defend all actions or proceedings in connection with the Collateral; and to do any and every act which such Borrower might
do in its own behalf; it being understood and agreed that this power of attorney shall be a power coupled with an interest and cannot be revoked. 
  

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 (d) Administrative Agent and each Lender is hereby granted an irrevocable, non-exclusive, royalty-free
license or other right to use, without charge, Borrowers’ labels, mask works, rights of use of any name, any other Intellectual Property and advertising matter, and any similar property as it pertains to the Collateral, in completing production
of, advertising for sale, and selling any Collateral and, in connection with Administrative Agent’s exercise of its rights under this Article, Borrowers’ rights under all licenses and all franchise agreements inure to Administrative
Agent’s and each Lender’s benefit. 
 ARTICLE 10 - EVENTS OF DEFAULT 
 Section 10.1 Events of Default. 
 For purposes of the Financing Documents, the occurrence of any of the following conditions and/or events, whether voluntary or involuntary, by operation of law or otherwise, shall constitute an “Event of Default”:

 (a) any Borrower shall fail to pay when due any principal, interest, premium or fee under any Financing Document or any other amount
payable under any Financing Document and such failure shall continue for five (5) days, or there shall occur any default in the performance of or compliance with Section 4.14; 
 (b) any Credit Party defaults in the performance of or compliance with any term contained in this Agreement or in any other Financing Document (other
than occurrences described in other provisions of this Section 10.1 for which a different grace or cure period is specified or for which no grace or cure period is specified and thereby constitute immediate Events of Default) and such default
is not remedied by the Credit Party or waived by Administrative Agent within (i) with respect to any default under Article 5, Section 4.1, Section 4.3(a), or Section 4.3(c), five (5) days of the occurrence of such default or
the event giving rise to such default; (ii) with respect to all other matters, twenty (20) days after the Borrower Representative receives written notice thereof from Administrative Agent; 
 (c) any representation, warranty, certification or statement made by any Credit Party or any other Person in any Financing Document or in any
certificate, financial statement or other document delivered pursuant to any Financing Document is incorrect in any respect (or in any material respect if such representation, warranty, certification or statement is not by its terms already
qualified as to materiality) when made (or deemed made); 
 (d)(i) failure of any Credit Party to pay when due or within any applicable grace
period any principal, interest or other amount on Debt (other than the Loans), or the occurrence of any breach, default, condition or event with respect to any Debt (other than the Loans), if the effect of such failure or occurrence is to cause or
to permit the holder or holders of any such Debt to cause, Debt or other liabilities having an individual principal amount in excess of $50,000 or having an aggregate principal amount in excess of $50,000 to become or be declared due prior to its
stated maturity; or (ii) the occurrence of any breach or default under any terms or provisions of any Subordinated Debt Document or under any agreement subordinating the Subordinated Debt to all or any portion of the Obligations or the
occurrence of any event requiring the prepayment of any Subordinated Debt; 
 (e) any Credit Party or any Subsidiary of a Borrower shall
commence a voluntary case or other proceeding seeking liquidation, reorganization or other relief with respect to itself or its debts under any bankruptcy, insolvency or other similar law now or hereafter in effect or seeking the appointment of a
trustee, receiver, liquidator, custodian or other similar official of it or any substantial part of its property, or shall consent to any such relief or to the appointment of or taking possession by any such official in an involuntary case or other
proceeding commenced against it, or shall make a general assignment for the benefit of creditors, or shall fail generally to pay its debts as they become due, or shall take any corporate action to authorize any of the foregoing; 
 (f) an involuntary case or other proceeding shall be commenced against any Credit Party or any Subsidiary of a Borrower seeking liquidation,
reorganization or other relief with respect to it or its debts under any bankruptcy, insolvency or other similar law now or hereafter in effect or seeking the appointment of a trustee, 

  

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receiver, liquidator, custodian or other similar official of it or any substantial part of its property, and such involuntary case or other proceeding shall
remain undismissed and unstayed for a period of forty-five (45) days; or an order for relief shall be entered against any Credit Party or any Subsidiary of a Borrower under applicable federal bankruptcy, insolvency or other similar law in
respect of (i) bankruptcy, liquidation, winding-up, dissolution or suspension of general operations, (ii) composition, rescheduling, reorganization, arrangement or readjustment of, or other relief from, or stay of proceedings to enforce,
some or all of the debts or obligations, or (iii) possession, foreclosure, seizure or retention, sale or other disposition of, or other proceedings to enforce security over, all or any substantial part of the assets of such Credit Party or
Subsidiary; 
 (g) (i) institution of any steps by any Person to terminate any Pension Plan of any Borrower, or any of its Subsidiaries or
ERISA Affiliates (if any such Pension Plan exists) if as a result of such termination any Credit Party or any ERISA Affiliate could be required to make a contribution to such Pension Plan, or could incur a liability or obligation to such Pension
Plan, in excess of $100,000, (ii) a contribution failure occurs with respect to any Pension Plan of any Borrower, or any of its Subsidiaries or ERISA Affiliates (if any such Pension Plan exists) sufficient to give rise to a Lien on any property
or assets of any Borrower or any of its Subsidiaries or ERISA Affiliates under Section 302(f) of ERISA, or (iii) there shall occur any complete withdrawal or partial withdrawal from a Multiemployer Plan by any Borrower, or any of its
Subsidiaries or ERISA Affiliate (if any such Multiemployer Plan to which any Borrower, or any of its Subsidiaries or ERISA Affiliate contributes exists) and the withdrawal liability (without unaccrued interest) of Borrowers, and their Subsidiaries
and ERISA Affiliates to Multiemployer Plans to which any of them contributes or has contributed (including any outstanding withdrawal liability that such Borrower, or any applicable Subsidiary or ERISA Affiliate has incurred on the date of such
withdrawal) exceeds $100,000; 
 (h) one or more judgments or orders for the payment of money (not paid or fully covered by insurance
maintained in accordance with the requirements of this Agreement and as to which the relevant insurance company has acknowledged coverage) aggregating in excess of $50,000 shall be rendered against any or all Credit Parties and either
(i) enforcement proceedings shall have been commenced by any creditor upon any such judgments or orders, or (ii) there shall be any period of twenty (20) consecutive days during which a stay of enforcement of any such judgments or
orders, by reason of a pending appeal, bond or otherwise, shall not be in effect; 
 (i) any Lien created by any of the Security Documents
shall at any time fail to constitute a valid and perfected Lien on all of the Collateral purported to be encumbered thereby, subject to no prior or equal Lien except Permitted Liens, or any Credit Party shall so assert; 
 (j) the institution by any Governmental Authority of criminal proceedings against any Credit Party; 
 (k) a default or event of default occurs under any guaranty of any portion of the Obligations; 
 (l) any Borrower makes any payment on account of any Debt that has been subordinated to any of the Obligations, other than payments specifically
permitted by the terms of such subordination; 
 (m) if the Principal Borrower is or becomes an entity whose equity is registered with the
SEC, and/or is publicly traded on and/or registered with a public securities exchange, the Principal Borrower’s equity fails to remain registered with the SEC in good standing, and/or such equity fails to remain publicly traded on and
registered with a public securities exchange; or 
 (n) the occurrence of any fact, event or circumstance that has or that could reasonably
be expected to result in a Material Adverse Effect, if such default shall have continued unremedied for a period of ten (10) days after written notice from Administrative Agent. 
 All cure periods provided for in this Section shall run concurrently with any cure period provided for in any applicable Financing Documents under which
the default occurred. 
 Section 10.2 Acceleration and Suspension or Termination of Term Loan Commitment. Upon the occurrence and
during the continuance of an Event of Default, Administrative Agent shall if required by Required 

  

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Lenders (but not until so requested), (a) by notice to Borrower Representative suspend or terminate the Term Loan Commitment and the obligations of
Administrative Agent and Lenders with respect thereto, in whole or in part (and, if in part, each Lender’s Term Loan Commitment shall be reduced in accordance with its Pro Rata Share), and/or (b) by notice to Borrower Representative
declare the Obligations to be, and the Obligations shall thereupon become, immediately due and payable without presentment, demand, protest or other notice of any kind, all of which are hereby waived by each Borrower and Borrowers will pay the same;
provided, however, that in the case of any of the Events of Default specified in Section 10.1(e) or 10.1(f) above, without any notice to any Borrower or any other act by Administrative Agent or the Lenders, the Term Loan Commitment and
the obligations of Administrative Agent and the Lenders with respect thereto shall thereupon immediately and automatically terminate and all of the Obligations shall become immediately and automatically due and payable without presentment, demand,
protest or other notice of any kind, all of which are hereby waived by each Borrower and Borrowers will pay the same. 
 Section 10.3
[RESERVED] 
 Section 10.4 Default Rate of Interest. At the election of Administrative Agent or Required Lenders, after the
occurrence of an Event of Default and for so long as it continues, the Loans and other Obligations shall bear interest at rates that are five percent (5.0%) per annum in excess of the rates otherwise payable under this Agreement; provided that,
notwithstanding anything to the contrary contained in the foregoing or otherwise in this Agreement, the increased rates of default interest provided for in this section shall be applicable automatically and immediately upon the occurrence and during
the continuance of any Event of Default occurring under Section 10.1(e) or 10.1(f) above without the necessity of any further affirmative action by any party. 
 Section 10.5 Setoff Rights. During the continuance of any Event of Default, each Lender is hereby authorized by each Borrower at any time or from time to time, with reasonably prompt subsequent notice to
such Borrower (any prior or contemporaneous notice being hereby expressly waived) to set off and to appropriate and to apply any and all (a) balances held by such Lender or any of such Lender’s Affiliates at any of its offices for the
account of such Borrower or any of its Subsidiaries (regardless of whether such balances are then due to such Borrower or its Subsidiaries), and (b) other property at any time held or owing by such Lender to or for the credit or for the account
of such Borrower or any of its Subsidiaries, against and on account of any of the Obligations; except that no Lender shall exercise any such right without the prior written consent of Administrative Agent. Any Lender exercising a right to set off
shall purchase for cash (and the other Lenders shall sell) interests in each of such other Lender’s Pro Rata Share of the Obligations as would be necessary to cause all Lenders to share the amount so set off with each other Lender in accordance
with their respective Pro Rata Share of the Obligations. Each Borrower agrees, to the fullest extent permitted by law, that any Lender and any of such Lender’s Affiliates may exercise its right to set off with respect to the Obligations as
provided in this Section. 
 Section 10.6 Application of Proceeds. Notwithstanding anything to the contrary contained in this
Agreement, upon the occurrence and during the continuance of an Event of Default, (a) each Borrower irrevocably waives the right to direct the application of any and all payments at any time or times thereafter received by Administrative Agent
from or on behalf of such Borrower or any other Credit Party of all or any part of the Obligations, and, as between Borrowers on the one hand and Administrative Agent and Lenders on the other, Administrative Agent shall have the continuing and
exclusive right to apply and to reapply any and all payments received against the Obligations in such manner as Administrative Agent may deem advisable notwithstanding any previous application by Administrative Agent, and (b) the proceeds of
any sale of, or other realization upon, all or any part of the Collateral shall be applied: first, to all fees, costs, indemnities, liabilities, obligations and expenses incurred by or owing to Administrative Agent with respect to this
Agreement, the other Financing Documents or the Collateral; second, to all fees, costs, indemnities, liabilities, obligations and expenses incurred by or owing to any Lender with respect to this Agreement, the other Financing Documents or the
Collateral; third, to accrued and unpaid interest on the Obligations (including any interest which, but for the provisions of the Bankruptcy Code, would have accrued on such amounts); fourth, to the principal amount of the Obligations
outstanding; and fifth to any other indebtedness or obligations of Borrowers owing to Administrative Agent or any Lender under the Financing Documents. Any balance remaining shall be delivered to Borrowers or to whoever may be lawfully
entitled to receive such balance or as a court of competent jurisdiction may direct. In carrying out the foregoing, (x) amounts received shall be applied in the numerical order provided until exhausted prior to the application to the next
succeeding category, and (y) each of the Persons entitled to receive a payment in any particular category shall receive an amount equal to its pro rata share of amounts available to be applied pursuant thereto for such category. 
  

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 Section 10.7 Waivers and Remedies. 
 (a) Except as otherwise provided for in this Agreement and to the fullest extent permitted by applicable law, each Borrower waives: (i) presentment,
demand and protest, and notice of presentment, dishonor, intent to accelerate, acceleration, protest, default, nonpayment, maturity, release, compromise, settlement, extension or renewal of any or all Financing Documents, the Notes or any other
notes, commercial paper, Accounts, contracts, Documents, Instruments, Chattel Paper and guaranties at any time held by Lenders on which any Borrower may in any way be liable, and hereby ratifies and confirms whatever Lenders may do in this regard;
(ii) all rights to notice and a hearing prior to Administrative Agent’s or any Lender’s taking possession or control of, or to Administrative Agent’s or any Lender’s replevy, attachment or levy upon, any Collateral or any
bond or security which might be required by any court prior to allowing Administrative Agent or any Lender to exercise any of its remedies; and (iii) the benefit of all valuation, appraisal, marshalling and exemption Laws. The rights and
remedies herein and therein provided shall be cumulative and not exclusive of any rights or remedies provided by law. Any reference in any Financing Document to the “continuing” nature of any Event of Default shall not be construed as
establishing or otherwise indicating that any Borrower or any other Credit Party has the independent right to cure any such Event of Default, but is rather presented merely for convenience should such Event of Default be waived in accordance with
the terms of the applicable Financing Documents. 
 (b) Each Borrower for itself and all its successors and assigns, (i) agrees that its
liability shall not be in any manner affected by any acquiescence in non-compliance, indulgence, extension of time, renewal, waiver, or modification made, granted or consented to by Administrative Agent or any Lender; (ii) consents to any
indulgences and all extensions of time, renewals, waivers, or modifications that may be granted by Administrative Agent or any Lender with respect to the payment or other provisions of the Financing Documents, and to any substitution, exchange or
release of the Collateral, or any part thereof, with or without substitution, and agrees to the addition or release of any Borrower, endorsers, guarantors, or sureties, or whether primarily or secondarily liable, without notice to any other Borrower
and without affecting its liability hereunder; (iii) agrees that its liability shall be unconditional and without regard to the liability of any other Borrower, Administrative Agent or any Lender for any tax on the indebtedness; and
(iv) to the fullest extent permitted by law, expressly waives the benefit of any statute or rule of law or equity now provided, or which may hereafter be provided, which would produce a result contrary to or in conflict with the foregoing.

 (c) Any delay or forbearance by Administrative Agent or any Lender in exercising any right or remedy under any of the Financing Documents,
or otherwise afforded by applicable law, including any failure to accelerate the maturity date of the Loans, shall not be a waiver of or preclude the exercise of any right or remedy nor shall it serve as a novation of the Notes or as a reinstatement
of the Loans or a waiver of such right of acceleration or the right to insist upon strict compliance of the terms of the Financing Documents. Administrative Agent’s or any Lender’s acceptance of payment of any sum secured by any of the
Financing Documents after the due date of such payment shall not be a waiver of Administrative Agent’s and such Lender’s right to either require prompt payment when due of all other sums so secured or to declare a default for failure to
make prompt payment. 
 (d) Without limiting the generality of anything contained in this Agreement or the other Financing Documents, each
Borrower agrees that if an Event of Default is continuing (i) Administrative Agent and Lenders shall not be subject to any “one action” or “election of remedies” law or rule, and (ii) all Liens and other rights,
remedies or privileges provided to Administrative Agent or Lenders shall remain in full force and effect until Administrative Agent or Lenders have exhausted all remedies against the Collateral and any other properties owned by Borrowers and the
Financing Documents and other security instruments or agreements securing the Loans have been foreclosed, sold and/or otherwise realized upon in satisfaction of Borrowers’ obligations under the Financing Documents. 
 (e) Administrative Agent shall have the right from time to time to partially foreclose upon any Collateral in any manner and for any amounts secured by
the Financing Documents then due and payable as determined by Administrative Agent in its sole discretion. Notwithstanding one or more partial foreclosures, any unforeclosed Collateral shall remain subject to the Financing Documents to secure
payment of sums secured by the Financing Documents and not previously recovered. To the fullest extent permitted by law, each Borrower, for itself and its successors and assigns, waives in the event of foreclosure of any or all of the Collateral any
equitable right otherwise available to any Credit Party which would require the separate sale of any of the Collateral or require 

  

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Administrative Agent or Lenders to exhaust their remedies against any part of the Collateral before proceeding against any other part of the Collateral; and
further in the event of such foreclosure each Borrower does hereby expressly consent to and authorize, at the option of Administrative Agent, the foreclosure and sale either separately or together of each part of the Collateral. 
 Section 10.8 Injunctive Relief. The parties acknowledge and agree that, in the event of a breach or threatened breach of any Credit
Party’s obligations under any Financing Documents, Administrative Agent and Lenders may have no adequate remedy in money damages and, accordingly, shall be entitled to an injunction (including, without limitation, a temporary restraining order,
preliminary injunction, writ of attachment, or order compelling an audit) against such breach or threatened breach, including, without limitation, maintaining any cash management and collection procedure described herein. However, no specification
in this Agreement of a specific legal or equitable remedy shall be construed as a waiver or prohibition against any other legal or equitable remedies in the event of a breach or threatened breach of any provision of this Agreement. Each Credit Party
waives, to the fullest extent permitted by law, the requirement of the posting of any bond in connection with such injunctive relief. By joining in the Financing Documents as a Credit Party, each Credit Party specifically joins in this Section as if
this Section were a part of each Financing Document executed by such Credit Party. 
 ARTICLE 11 - ADMINISTRATIVE AGENT 
 Section 11.1 Appointment and Authorization. Each Lender hereby irrevocably appoints and authorizes Administrative Agent to be the agent of
Lender under and with respect to this Agreement and the other Financing Documents and to enter into each of the Financing Documents to which it is a party (other than this Agreement) on its behalf and to take such actions as Administrative Agent on
its behalf and to exercise such powers under the Financing Documents as are delegated to Administrative Agent by the terms thereof, together with all such powers as are reasonably incidental thereto. Subject to the terms of Section 12.5 and to
the terms of the other Financing Documents, Administrative Agent is authorized and empowered to amend, modify, or waive any provisions of this Agreement or the other Financing Documents on behalf of Lenders. The provisions of this Article 11 are
solely for the benefit of Administrative Agent and Lenders and neither Borrowers nor any other Credit Party shall have any rights as a third party beneficiary of any of the provisions hereof. In performing its functions and duties under this
Agreement, Administrative Agent shall act solely as agent of Lenders and does not assume and shall not be deemed to have assumed any obligation toward or relationship of agency or trust with or for Borrowers or any other Credit Party. Administrative
Agent may perform any of its duties hereunder, or under the Financing Documents, by or through its own agents or employees. 
 Section 11.2 Administrative Agent and Affiliates. Administrative Agent shall have the same rights and powers under the Financing Documents as any other Lender and may exercise or refrain from exercising the same as though it
were not Administrative Agent, and Administrative Agent and its Affiliates may lend money to, invest in and generally engage in any kind of business with each Credit Party or Affiliate of any Credit Party as if it were not Administrative Agent
hereunder. 
 Section 11.3 Action by Administrative Agent. The duties of Administrative Agent shall be mechanical and
administrative in nature. Administrative Agent shall not have by reason of this Agreement a fiduciary relationship in respect of any Lender. Nothing in this Agreement or any of the Financing Documents is intended to or shall be construed to impose
upon Administrative Agent any obligations in respect of this Agreement or any of the Financing Documents except as expressly set forth herein or therein. 
 Section 11.4 Consultation with Experts. Administrative Agent may consult with legal counsel, independent public accountants and other experts selected by it and shall not be liable for any action taken or
omitted to be taken by it in good faith in accordance with the advice of such counsel, accountants or experts. 
 Section 11.5
Liability of Administrative Agent. Neither Administrative Agent nor any of its directors, officers, agents or employees shall be liable to any Lender for any action taken or not taken by it in connection with the Financing Documents, except that
Administrative Agent shall be liable with respect to its specific duties set forth hereunder, but only to the extent of its own gross negligence or willful misconduct in the discharge thereof as determined by a final non-appealable judgment of a
court of competent jurisdiction. Neither Administrative Agent nor any of its directors, officers, agents or employees shall be responsible for or have any duty 

  

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to ascertain, inquire into or verify (i) any statement, warranty or representation made in connection with any Financing Document or any borrowing
hereunder; (ii) the performance or observance of any of the covenants or agreements specified in any Financing Document; (iii) the satisfaction of any condition specified in any Financing Document; (iv) the validity, effectiveness,
sufficiency or genuineness of any Financing Document, any Lien purported to be created or perfected thereby or any other instrument or writing furnished in connection therewith; (v) the existence or non-existence of any Default or Event of
Default; or (vi) the financial condition of any Credit Party. Administrative Agent shall not incur any liability by acting in reliance upon any notice, consent, certificate, statement, or other writing (which may be a bank wire, telex,
facsimile or electronic transmission or similar writing) believed by it to be genuine or to be signed by the proper party or parties. Administrative Agent shall not be liable for any apportionment or distribution of payments made by it in good faith
and if any such apportionment or distribution is subsequently determined to have been made in error the sole recourse of any Lender to whom payment was due but not made, shall be to recover from other Lenders any payment in excess of the amount to
which they are determined to be entitled (and such other Lenders hereby agree to return to such Lender any such erroneous payments received by them). 
 Section 11.6 Indemnification. Each Lender shall, in accordance with its Pro Rata Share, indemnify Administrative Agent (to the extent not reimbursed by Borrowers) upon demand against any cost, expense
(including reasonable counsel fees and disbursements), claim, demand, action, loss or liability (except such as result from Administrative Agent’s gross negligence or willful misconduct as determined by a final non-appealable judgment of a
court of competent jurisdiction) that Administrative Agent may suffer or incur in connection with the Financing Documents or any action taken or omitted by Administrative Agent hereunder or thereunder. If any indemnity furnished to Administrative
Agent for any purpose shall, in the opinion of Administrative Agent, be insufficient or become impaired, Administrative Agent may call for additional indemnity and cease, or not commence, to do the acts indemnified against even if so directed by
Required Lenders until such additional indemnity is furnished. 
 Section 11.7 Right to Request and Act on Instructions.
Administrative Agent may at any time request instructions from Lenders with respect to any actions or approvals which by the terms of this Agreement or of any of the Financing Documents Administrative Agent is permitted or desires to take or to
grant, and if such instructions are promptly requested, Administrative Agent shall be absolutely entitled to refrain from taking any action or to withhold any approval and shall not be under any liability whatsoever to any Person for refraining from
any action or withholding any approval under any of the Financing Documents until it shall have received such instructions from Required Lenders or all or such other portion of the Lenders as shall be prescribed by this Agreement. Without limiting
the foregoing, no Lender shall have any right of action whatsoever against Administrative Agent as a result of Administrative Agent acting or refraining from acting under this Agreement or any of the other Financing Documents in accordance with the
instructions of Required Lenders (or all or such other portion of the Lenders as shall be prescribed by this Agreement) and, notwithstanding the instructions of Required Lenders (or such other applicable portion of the Lenders), Administrative Agent
shall have no obligation to take any action if it believes, in good faith, that such action would violate applicable Laws or exposes Administrative Agent to any liability for which it has not received satisfactory indemnification in accordance with
the provisions of Section 11.6. 
 Section 11.8 Credit Decision. Each Lender acknowledges that it has, independently and
without reliance upon Administrative Agent or any other Lender, and based on such documents and information as it has deemed appropriate, made its own credit analysis and decision to enter into this Agreement. Each Lender also acknowledges that it
will, independently and without reliance upon Administrative Agent or any other Lender, and based on such documents and information as it shall deem appropriate at the time, continue to make its own credit decisions in taking or not taking any
action under the Financing Documents. 
 Section 11.9 Collateral Matters. Lenders irrevocably authorize Administrative Agent, at
its option and in its discretion, to (x) release any Lien granted to or held by Administrative Agent under any Security Document (i) upon termination of the Term Loan Commitment and payment in full of all Obligations; or
(ii) constituting property sold or disposed of as part of or in connection with any disposition permitted under any Financing Document (it being understood and agreed that Administrative Agent may conclusively rely without further inquiry on a
certificate of a Responsible Officer as to the sale or other disposition of property being made in full compliance with the provisions of the Financing Documents) and (y) release or subordinate any Lien granted to 

  

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or held by Administrative Agent under any Security Document constituting property which is the subject of a Permitted Asset Disposition (it being understood
and agreed that Administrative Agent may conclusively rely without further inquiry on a certificate of a Responsible Officer as to the identification of any property which is the subject of a Permitted Asset Disposition). Upon request by
Administrative Agent at any time, Lenders will confirm Administrative Agent’s authority to release and/or subordinate particular types or items of Collateral pursuant to this Section. 
 Section 11.10 Agency for Perfection. Administrative Agent and each Lender hereby appoint each other Lender as agent for the purpose of
perfecting Administrative Agent’s security interest in assets which, in accordance with the Uniform Commercial Code in any applicable jurisdiction, can be perfected by possession or control. Should any Lender (other than Administrative Agent)
obtain possession or control of any such assets, such Lender shall notify Administrative Agent thereof, and, promptly upon Administrative Agent’s request therefor, shall deliver such assets to Administrative Agent or in accordance with
Administrative Agent’s instructions or transfer control to Administrative Agent in accordance with Administrative Agent’s instructions. Each Lender agrees that it will not have any right individually to enforce or seek to enforce any
Security Document or to realize upon any Collateral for the Loans unless instructed to do so by Administrative Agent (or consented to by Administrative Agent, as provided in Section 10.5), it being understood and agreed that such rights and
remedies may be exercised only by Administrative Agent. 
 Section 11.11 Notice of Default. Administrative Agent shall not be
deemed to have knowledge or notice of the occurrence of any Default or Event of Default except with respect to defaults in the payment of principal, interest and fees required to be paid to Administrative Agent for the account of Lenders, unless
Administrative Agent shall have received written notice from a Lender or Borrower referring to this Agreement, describing such Default or Event of Default and stating that such notice is a “notice of default”. Administrative Agent will
notify each Lender of its receipt of any such notice. Administrative Agent shall take such action with respect to such Default or Event of Default as may be requested by Required Lenders (or all or such other portion of the Lenders as shall be
prescribed by this Agreement) in accordance with the terms hereof. Unless and until Administrative Agent has received any such request, Administrative Agent may (but shall not be obligated to) take such action, or refrain from taking such action,
with respect to such Default or Event of Default as it shall deem advisable or in the best interests of Lenders. 
 Section 11.12
Successor Administrative Agent. Administrative Agent may at any time give notice of its resignation to the Lenders and Borrowers. Upon receipt of any such notice of resignation, Required Lenders shall have the right, without the requirement of
any consent of Borrowers, to appoint a successor Administrative Agent. Upon the acceptance of a successor’s appointment as Administrative Agent hereunder and notice of such acceptance to the retiring Administrative Agent, such successor shall
succeed to and become vested with all of the rights, powers, privileges and duties of the retiring (or retired) Administrative Agent, the retiring Administrative Agent’s resignation shall become immediately effective and the retiring
Administrative Agent shall be discharged from all of its duties and obligations hereunder and under the other Financing Documents (if such resignation was not already effective and such duties and obligations not already discharged, as provided
below in this paragraph). The fees payable by Borrowers to a successor Administrative Agent shall be the same as those payable to its predecessor unless otherwise agreed between Borrowers and such successor. If no such successor shall have been so
appointed by Required Lenders and shall have accepted such appointment within thirty (30) days after the retiring Administrative Agent gives notice of its resignation, then the retiring Administrative Agent may on behalf of the Lenders (but
without any obligation) appoint a successor Administrative Agent. From and following the expiration of such thirty (30) day period, Administrative Agent shall have the exclusive right, upon one (1) Business Days’ notice to Borrowers
and the Lenders, and the delivery to a Lender, for the benefit of all Lenders, of all Collateral in the possession of the retiring Administrative Agent, to make its resignation effective immediately. From and following the effectiveness of such
notice, (i) the retiring Administrative Agent shall be discharged from its duties and obligations hereunder and under the other Financing Documents and (ii) all payments, communications and determinations provided to be made by, to or
through Administrative Agent shall instead be made by or to each Lender directly, until such time as Required Lenders appoint a successor Administrative Agent as provided for above in this paragraph. The provisions of this Agreement shall continue
in effect for the benefit of any retiring Administrative Agent and its sub-agents after the effectiveness of its resignation hereunder and under the other Financing Documents in respect of any actions taken or omitted to be taken by any of them
while the retiring Administrative Agent was acting or was continuing to act as Administrative Agent. 
  

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 Section 11.13 Disbursements of Loans; Payment and Sharing of Payment.

 (a) Loan Advances, Payments and Settlements; Interest and Fee Payments. 
 (i) Administrative Agent shall have the right, on behalf of Lenders (other than Non-Funding Lenders) to disburse funds to Borrowers for all Loans or
advances thereof requested or deemed requested by Borrowers pursuant to the terms of this Agreement so long as Administrative Agent has no knowledge of any Default or Event of Default. Administrative Agent shall be conclusively entitled to assume,
for purposes of the preceding sentence, that each Lender, other than any Non-Funding Lenders, will fund its Pro Rata Share of all Loans and advances thereof requested by Borrowers. Each Lender (other than any Non-Funding Lender) shall reimburse
Administrative Agent on demand, in accordance with the provisions of the immediately following paragraph, for all funds disbursed on its behalf by Administrative Agent pursuant to the first sentence of this clause (i), or if Administrative Agent so
requests, each Lender (other than any Non-Funding Lender) will remit to Administrative Agent its Pro Rata Share of any Loan or advance thereof before Administrative Agent disburses the same to Borrowers. If Administrative Agent elects to require
that each Lender (other than any Non-Funding Lender) make funds available to Administrative Agent, prior to a disbursement by Administrative Agent to Borrowers, Administrative Agent shall advise each Lender by telephone, facsimile or e-mail of the
amount of such Lender’s Pro Rata Share of the Loan or advance thereof requested by Borrowers no later than noon (Chicago time) on the date of funding of such Loan or advance, and each such Lender shall pay Administrative Agent on such date such
Lender’s Pro Rata Share of such requested Loan or advance, in same day funds, by wire transfer to the Payment Account, or such other account as may be identified by Administrative Agent to Lenders from time to time. If any Lender fails to pay
the amount of its Pro Rata Share within one (1) Business Day after Administrative Agent’s demand, Administrative Agent shall promptly notify Borrowers, and Borrowers shall immediately repay such amount to Administrative Agent. Any
repayment required by Borrowers pursuant to this Section shall be accompanied by accrued interest thereon from and including the date such amount is made available to Borrowers to but excluding the date of payment at the rate of interest then
applicable to the applicable Loan under which the advance is made. Nothing in this Section or elsewhere in this Agreement or the other Financing Documents shall be deemed to require Administrative Agent to advance funds on behalf of any Lender or to
relieve any Lender from its obligation to fulfill its commitments hereunder or to prejudice any rights that Administrative Agent or Borrowers may have against any Lender as a result of any default by such Lender hereunder. 
 (ii) On a Business Day of each week as selected from time to time by Administrative Agent, or more frequently (including daily), if Administrative Agent
so elects (each such day being a “Settlement Date”), Administrative Agent will advise each Lender by telephone, facsimile or e-mail of the amount of each such Lender’s percentage interest of the applicable Loan balance as of
the close of business of the Business Day immediately preceding the Settlement Date. In the event that payments are necessary to adjust the amount of such Lender’s actual percentage interest of the applicable Loan balance to such Lender’s
required percentage interest of the applicable Loan balance as of any Settlement Date, the party from which such payment is due shall pay Administrative Agent, without setoff or discount, to the Payment Account not later than noon (Chicago time) on
the Business Day following the Settlement Date the full amount necessary to make such adjustment. Any obligation arising pursuant to the immediately preceding sentence shall be absolute and unconditional and shall not be affected by any circumstance
whatsoever. In the event settlement shall not have occurred by the date and time specified in the second preceding sentence, interest shall accrue on the unsettled amount at the Federal Funds Rate, for the first three (3) days following the
scheduled date of settlement, and thereafter at the Base Rate plus the Base Rate Margin applicable to the applicable Loan under which the advance is made. 
 (iii) On each Settlement Date, Administrative Agent shall advise each Lender by telephone, facsimile or e-mail of the amount of such Lender’s percentage interest of principal, interest and fees paid for the
benefit of Lenders with respect to each applicable Loan, to the extent of such Lender’s Term Loan Exposure with respect thereto, and shall make payment to such Lender not later than noon (Chicago time) on the Business Day following the
Settlement Date of such amounts in accordance with wire instructions delivered by such Lender to Administrative Agent, as the same may be modified from time to time by written notice to Administrative Agent; provided, that, in the case such Lender
is a Defaulted Lender, Administrative Agent shall be entitled to set off the funding short-fall against that Defaulted Lender’s respective share of all payments received from Borrowers. 
  

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 (iv) On the Closing Date, Administrative Agent, on behalf of the Lenders, may elect to advance to
Borrowers the full amount of the initial Loans to be made on the Closing Date prior to receiving funds from the Lenders, in reliance upon each Lender’s commitment to make its Pro Rata Share of such Loans to Borrowers in a timely manner on such
date. If Administrative Agent elects to advance the initial Loans to Borrowers in such manner, Administrative Agent shall be entitled to receive all interest that accrues on the Closing Date on each Lender’s Pro Rata Share of such Loans unless
Administrative Agent receives such Lender’s Pro Rata Share of such Loans by 3:00 p.m. (Chicago time) on the Closing Date. 
 (v)
Notwithstanding anything to the contrary in this Agreement, repayment of Loans by Administrative Agent shall be made first in respect of Loans made at the time any Non-Funding Lenders exist, and second in respect of all other outstanding Loans.

 (vi) The provisions of this Section 11.13(a) shall be deemed to be binding upon Administrative Agent and Lenders notwithstanding the
occurrence of any Default or Event of Default, or any insolvency or bankruptcy proceeding pertaining to Borrowers or any other Credit Party. 
 (b) Term Loan Payments. Payments of principal, interest and fees in respect of the Term Loans will be settled on the date of receipt if received by Administrative Agent on the last Business Day of a month or on the Business Day
immediately following the date of receipt if received on any day other than the last Business Day of a month. 
 (c) Return of Payments.

 (i) If Administrative Agent pays an amount to a Lender under this Agreement in the belief or expectation that a related payment has
been or will be received by Administrative Agent from Borrowers and such related payment is not received by Administrative Agent, then Administrative Agent will be entitled to recover such amount from such Lender on demand without setoff,
counterclaim or deduction of any kind, together with interest accruing on a daily basis at the Federal Funds Rate. 
 (ii) If Administrative
Agent determines at any time that any amount received by Administrative Agent under this Agreement must be returned to Borrowers or paid to any other Person pursuant to any insolvency law or otherwise, then, notwithstanding any other term or
condition of this Agreement or any other Financing Document, Administrative Agent will not be required to distribute any portion thereof to any Lender. In addition, each Lender will repay to Administrative Agent on demand any portion of such amount
that Administrative Agent has distributed to such Lender, together with interest at such rate, if any, as Administrative Agent is required to pay to Borrowers or such other Person, without setoff, counterclaim or deduction of any kind. 

(d) Defaulted Lenders. The failure of any Defaulted Lender to make any Loan or any payment required by it hereunder shall not relieve any other
Lender of its obligations to make its percentage amount of such Loan or payment, but neither any other Lender nor Administrative Agent shall be responsible for the failure of any Defaulted Lender to make a Loan or make any other payment required
hereunder. Notwithstanding anything set forth herein to the contrary, a Defaulted Lender shall not have any voting or consent rights under or with respect to any Financing Document or constitute a “Lender” (or be included in the
calculation of “Required Lenders” hereunder) for any voting or consent rights under or with respect to any Financing Document. 
 (e) Sharing of Payments. If any Lender shall obtain any payment or other recovery (whether voluntary, involuntary, by application of setoff or otherwise) on account of any Loan (other than pursuant to the terms of Sections 2.9(d)) in
excess of its pro rata share of payments entitled pursuant to the other provisions of this Section, such Lender shall purchase from the other Lenders such participations in extensions of credit made by such other Lenders (without recourse,
representation or warranty) as shall be necessary to cause such purchasing Lender to share the excess payment or other recovery ratably with each of them; provided, however, that if all or any portion of the excess payment or other recovery is
thereafter required to be returned or otherwise recovered from such purchasing Lender, such portion of such purchase shall be rescinded and each Lender which has sold a participation to the purchasing Lender shall repay to the purchasing Lender the
purchase price to the ratable extent of such return or recovery, without interest. Borrowers agree that any Lender so purchasing a participation from another Lender pursuant to this clause (e) may, to the fullest extent permitted by law,
exercise all its rights of 

  

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payment (including pursuant to Section 10.5) with respect to such participation as fully as if such Lender were the direct creditor of Borrowers in the
amount of such participation. If under any applicable bankruptcy, insolvency or other similar law, any Lender receives a secured claim in lieu of a setoff to which this clause (e) applies, such Lender shall, to the extent practicable, exercise
its rights in respect of such secured claim in a manner consistent with the rights of the Lenders entitled under this clause (e) to share in the benefits of any recovery on such secured claim. 
 Section 11.14 Right to Perform, Preserve and Protect. If any Credit Party fails to perform any obligation hereunder or under any other
Financing Document, Administrative Agent itself may, but shall not be obligated to, cause such obligation to be performed at Borrowers’ expense. Administrative Agent is further authorized by Borrowers and the Lenders to make expenditures from
time to time which Administrative Agent, in its reasonable business judgment, deems necessary or desirable to (i) preserve or protect the business conducted by Borrowers, the Collateral, or any portion thereof and/or (ii) enhance the
likelihood of, or maximize the amount of, repayment of the Loans and other Obligations. Borrowers hereby agree to reimburse Administrative Agent on demand for any and all costs, liabilities and obligations incurred by Administrative Agent pursuant
to this Section. Each Lender hereby agrees to indemnify Administrative Agent upon demand for any and all costs, liabilities and obligations incurred by Administrative Agent pursuant to this Section, in accordance with the provisions of
Section 11.6. 
 Section 11.15 Additional Titled Agents. Except for rights and powers, if any, expressly reserved under this
Agreement to any bookrunner, arranger or to any titled agent named on the cover page of this Agreement, other than Administrative Agent (collectively, the “Additional Titled Agents”), and except for obligations, liabilities, duties
and responsibilities, if any, expressly assumed under this Agreement by any Additional Titled Agent, no Additional Titled Agent, in such capacity, has any rights, powers, liabilities, duties or responsibilities hereunder or under any of the other
Financing Documents. Without limiting the foregoing, no Additional Titled Agent shall have nor be deemed to have a fiduciary relationship with any Lender. At any time that any Lender serving as an Additional Titled Agent shall have transferred to
any other Person (other than any Affiliates) all of its interests in the Loans and in the Term Loan Commitment, such Lender shall be deemed to have concurrently resigned as such Additional Titled Agent. 
 Section 11.16 Definitions. As used in this Article 11, the following term has the following meaning: 
 “Federal Funds Rate” means, for any day, the rate of interest per annum (rounded upwards, if necessary, to the nearest whole multiple of
1/100 of 1%) equal to the weighted average of the rates on overnight Federal funds transactions with members of the Federal Reserve System arranged by Federal funds brokers on such day, as published by the Federal Reserve Bank of New York on the
Business Day next succeeding such day, provided, however, that (a) if such day is not a Business Day, the Federal Funds Rate for such day shall be such rate on such transactions on the next preceding Business Day, and (b) if no such
rate is so published on such next preceding Business Day, the Federal Funds Rate for such day shall be the average rate quoted to Administrative Agent on such day on such transactions as determined by Administrative Agent. 
 ARTICLE 12 - MISCELLANEOUS 
 Section 12.1 Survival. All agreements, representations and warranties made herein and in every other Financing Document shall survive the execution and delivery of this Agreement and the other Financing Documents. The provisions
of Section 2.8 and Articles 11 and 12 shall survive the payment of the Obligations (both with respect to any Lender and all Lenders collectively) and any termination of this Agreement and any judgment with respect to any Obligations, including
any final foreclosure judgment with respect to any Security Document, and no unpaid or unperformed, current or future, Obligations will merge into any such judgment. 
 Section 12.2 Time. Time is of the essence in each Borrower’s and each other Credit Party’s performance under this Agreement and all other Financing Documents. 
  

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 Section 12.3 Notices. 
 (a) All notices, requests and other communications to any party hereunder shall be in writing (including prepaid overnight courier, facsimile transmission
or similar writing) and shall be given to such party at its address, facsimile number or e-mail address set forth on the signature pages hereof (or, in the case of any such Lender who becomes a Lender after the date hereof, in an assignment
agreement or in a notice delivered to Borrower Representative and Administrative Agent by the assignee Lender forthwith upon such assignment) or at such other address, facsimile number or e-mail address as such party may hereafter specify for the
purpose by notice to Administrative Agent and Borrower Representative; provided, however, that notices, requests or other communications shall be permitted by electronic means only in accordance with the provisions of
Section 12.3(b) and (c). Each such notice, request or other communication shall be effective (i) if given by facsimile, when such notice is transmitted to the facsimile number specified by this Section and the sender receives a
confirmation of transmission from the sending facsimile machine, or (ii) if given by mail, prepaid overnight courier or any other means, when received or when receipt is refused at the applicable address specified by this Section 12.3(a).

 (b) Notices and other communications to the parties hereto may be delivered or furnished by electronic communication (including e-mail and
Internet or intranet websites) pursuant to procedures approved from time to time by Administrative Agent, provided, however, that the foregoing shall not apply to notices sent directly to any Lender if such Lender has notified the
Administrative Agent that it is incapable of receiving notices by electronic communication. The Administrative Agent or Borrower Representative may, in their discretion, agree to accept notices and other communications to them hereunder by
electronic communications pursuant to procedures approved by it, provided, however, that approval of such procedures may be limited to particular notices or communications. 
 (c) Unless the Administrative Agent otherwise prescribes, (i) notices and other communications sent to an e-mail address shall be deemed received
upon the sender’s receipt of an acknowledgment from the intended recipient (such as by the “return receipt requested” function, as available, return e-mail or other written acknowledgment), and (ii) notices or communications
posted to an Internet or intranet website shall be deemed received upon the deemed receipt by the intended recipient at its e-mail address as described in the foregoing clause (i) of notification that such notice or communication is available
and identifying the website address therefor, provided, however, that if any such notice or other communication is not sent or posted during normal business hours, such notice or communication shall be deemed to have been sent at the
opening of business on the next Business Day. 
 Section 12.4 Severability. In case any provision of or obligation under this
Agreement or any other Financing Document shall be invalid, illegal or unenforceable in any jurisdiction, the validity, legality and enforceability of the remaining provisions or obligations, or of such provision or obligation in any other
jurisdiction, shall not in any way be affected or impaired thereby. 
 Section 12.5 Amendments and Waivers. 
 (a) No provision of this Agreement or any other Financing Document may be amended, waived or otherwise modified unless such amendment, waiver or other
modification is in writing and is signed or otherwise approved by Borrowers, the Administrative Agent and the Required Lenders; provided that 
 (i) no such amendment, waiver or other modification that would have the effect of increasing or reducing a Lender’s Term Loan Commitment Amount or Term Loan Commitment Percentage shall be effective as to such Lender without such
Lender’s written consent; 
 (ii) no such amendment, waiver or modification that would affect the rights and duties of Administrative
Agent shall be effective without Administrative Agent’s written consent or signature; and 
 (iii) no such amendment, waiver or other
modification shall, unless signed by all the Lenders directly affected thereby, (A) reduce the principal of, rate of interest on or any fees with respect to any Loan or forgive any principal, interest (other than default interest) or fees
(other than late charges) with respect to any Loan (B) postpone the date fixed for, or waive, any payment of principal of any Loan or of interest on any Loan (other than default interest) or any fees provided for hereunder (other than late
charges or for any termination of any commitment; (C) change the definition of the term Required Lenders or the percentage of Lenders which shall be 

  

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required for Lenders to take any action hereunder; (D) release all or substantially all or any material portion of the Collateral, authorize any
Borrower to sell or otherwise dispose of all or substantially all or any material portion of the Collateral or release any guarantor of all or any portion of the Obligations or its guaranty obligations with respect thereto, except, in each case with
respect to this clause (D), as otherwise may be expressly permitted under this Agreement or the other Financing Documents (including in connection with any disposition permitted hereunder); (E) amend, waive or otherwise modify this
Section 12.5 or the definitions of the terms used in this Section 12.5 insofar as the definitions affect the substance of this Section 12.5; (F) consent to the assignment, delegation or other transfer by any Credit Party of any
of its rights and obligations under any Financing Document or release any Borrower of its payment obligations under any Financing Document, except, in each case with respect to this clause (F), pursuant to a merger or consolidation permitted
pursuant to this Agreement or (G) amend any of the provisions of Section 10.6 or amend any of the definitions Pro Rata Share, Term Loan Commitment, Term Loan Commitment Amount, Term Loan Commitment Percentage or that provide for the
Lenders to receive their Pro Rata Shares of any fees, payments, setoffs or proceeds of Collateral hereunder. It is hereby understood and agreed that all Lenders shall be deemed directly affected by an amendment, waiver or other modification of the
type described in the preceding clauses (C), (D), (E), (F) and (G) of the preceding sentence. 
 Section 12.6 Assignments;
Participations; Replacement of Lenders. 
 (a) Assignments. 
 (i) Any Lender may at any time assign to one or more Eligible Assignees all or any portion of such Lender’s Loans and interest in the Term Loan
Commitment, together with all related obligations of such Lender hereunder. Except as Administrative Agent may otherwise agree, the amount of any such assignment (determined as of the date of the applicable Assignment Agreement or, if a “Trade
Date” is specified in such Assignment Agreement, as of such Trade Date) shall be in a minimum aggregate amount equal to $1,000,000 or, if less, the assignor’s entire interests in the Term Loan Commitment and outstanding Loans; provided,
that, in connection with simultaneous assignments to two or more related Approved Assignees, such Approved Assignees shall be treated as one assignee for purposes of determining compliance with the minimum assignment size referred to
above. Borrowers and Administrative Agent shall be entitled to continue to deal solely and directly with such Lender in connection with the interests so assigned to an Eligible Assignee until Administrative Agent shall have received and accepted an
effective Assignment Agreement executed, delivered and fully completed by the applicable parties thereto, such other information regarding such Eligible Assignee as Administrative Agent reasonably shall require and a processing fee of $3,500;
provided, only one processing fee shall be payable in connection with simultaneous assignments to two or more related Approved Assignees. 
 (ii) From and after the date on which the conditions described above have been met, (i) such Eligible Assignee shall be deemed automatically to have become a party hereto and, to the extent of the interests assigned to such Eligible
Assignee pursuant to such Assignment Agreement, shall have the rights and obligations of a Lender hereunder and (ii) the assigning Lender, to the extent that rights and obligations hereunder have been assigned by it pursuant to such Assignment
Agreement, shall be released from its rights and obligations hereunder (other than those that survive termination pursuant to Section 12.1). Upon the request of the Eligible Assignee (and, as applicable, the assigning Lender) pursuant to an
effective Assignment Agreement, Borrowers shall execute and deliver to Administrative Agent for delivery to the Eligible Assignee (and, as applicable, the assigning Lender) Notes in the aggregate principal amount of the Eligible Assignee’s
percentage interest in the Term Loan Commitment (and, as applicable, Notes in the principal amount of that portion of the Term Loan Commitment retained by the assigning Lender). Upon receipt by the assigning Lender of such Note, the assigning Lender
shall return to Borrowers any prior Note held by it. 
 (iii) Administrative Agent, acting solely for this purpose as an agent of Borrower,
shall maintain at its offices located in Chicago, Illinois a copy of each Assignment Agreement delivered to it and a register for the recordation of the names and addresses of each Lender, and the commitments of, and principal amount of the Loans
owing to, such Lender pursuant to the terms hereof. The entries in such register shall be conclusive, and Borrower, Administrative Agent and Lenders may treat each Person whose name is recorded therein pursuant to the terms hereof as a Lender
hereunder for all purposes of this Agreement, notwithstanding notice to the contrary. Such register shall be available for inspection by Borrowers and any Lender, at any reasonable time upon reasonable prior notice to Administrative Agent.

  

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 (iv) Notwithstanding the foregoing provisions of this Section 12.6(a) or any other provision of this
Agreement, any Lender may at any time pledge or assign a security interest in all or any portion of its rights under this Agreement to secure obligations of such Lender, including any pledge or assignment to secure obligations to a Federal Reserve
Bank; provided that no such pledge or assignment shall release such Lender from any of its obligations hereunder or substitute any such pledgee or assignee for such Lender as a party hereto. 
 (v) Notwithstanding the foregoing provisions of this Section 12.6(a) or any other provision of this Agreement, Administrative Agent has the right,
but not the obligation, to effectuate assignments of Loans and Term Loan Commitments via an electronic settlement system acceptable to Administrative Agent as designated in writing from time to time to the Lenders by Administrative Agent (the
“Settlement Service”). At any time when the Administrative Agent elects, in its sole discretion, to implement such Settlement Service, each such assignment shall be effected by the assigning Lender and proposed assignee pursuant to
the procedures then in effect under the Settlement Service, which procedures shall be consistent with the other provisions of this Section 12.6(a). Each assigning Lender and proposed Eligible Assignee shall comply with the requirements of the
Settlement Service in connection with effecting any assignment of Loans and Term Loan Commitments pursuant to the Settlement Service. With the prior approval of each of Administrative Agent and the Borrower, Administrative Agent’s and the
Borrower’s approval of such Eligible Assignee shall be deemed to have been automatically granted with respect to any transfer effected through the Settlement Service (without any cost to Lender except for the processing fee referred to in
clause (i) above). Assignments and assumptions of the Loans and Term Loan Commitments shall be effected by the provisions otherwise set forth herein until Administrative Agent notifies Lenders of the Settlement Service as set forth herein.

 (b) Participations. Any Lender may at any time, without the consent of, or notice to, Borrowers or Administrative Agent, sell to
one or more Persons participating interests in its Loans, commitments or other interests hereunder (any such Person, a “Participant”). In the event of a sale by a Lender of a participating interest to a Participant, (a) such
Lender’s obligations hereunder shall remain unchanged for all purposes, (b) Borrowers and Administrative Agent shall continue to deal solely and directly with such Lender in connection with such Lender’s rights and obligations
hereunder and (c) all amounts payable by Borrowers shall be determined as if such Lender had not sold such participation and shall be paid directly to such Lender. No Participant shall have any direct or indirect voting rights hereunder except
with respect to any event described in Section 12.5 expressly requiring the unanimous vote of all Lenders or, as applicable, all affected Lenders. Borrowers agree that if amounts outstanding under this Agreement are due and payable (as a result
of acceleration or otherwise), each Participant shall be deemed to have the right of set-off in respect of its participating interest in amounts owing under this Agreement to the same extent as if the amount of its participating interest were owing
directly to it as a Lender under this Agreement; provided that such right of set-off shall be subject to the obligation of each Participant to share with Lenders, and Lenders agree to share with each Participant, as provided in
Section 10.5. 
 (c) Replacement of Lenders. Within thirty (30) days after: (i) receipt by Administrative Agent of
notice and demand from any Lender for payment of additional costs as provided in Section 2.8(d), which demand shall not have been revoked, (ii) Borrowers are required to pay any additional amount to any Lender or any Governmental Authority
for the account of any Lender pursuant to Section 2.8(a), (iii) any Lender is a Defaulted Lender, and the circumstances causing such status shall not have been cured or waived, or (iv) any failure by any Lender to consent to a
requested amendment, waiver or modification to any Financing Document in which Required Lenders have already consented to such amendment, waiver or modification but the consent of each Lender, or each Lender affected thereby, is required with
respect thereto (each relevant Lender in the foregoing clauses (i) through (iv) being an “Affected Lender”), Administrative Agent may, at its option, notify such Affected Lender of such Person’s intention to obtain,
at Borrowers’ expense, a replacement Lender (“Replacement Lender”) for such Lender, which Replacement Lender shall be an Eligible Assignee and, in the event the Replacement Lender is to replace an Affected Lender described in
the preceding clause (iv), such Replacement Lender consents to the requested amendment, waiver or modification making the replaced Lender an Affected Lender. In the event Administrative Agent obtains a Replacement Lender within ninety (90) days
following notice of its intention to do so, the Affected Lender shall sell, at par, plus accrued but unpaid interest, and assign all of its Loans and funding commitments hereunder to such Replacement Lender in accordance with the procedures set
forth in Section 12.6(a); provided, that (i) Borrowers shall have, as applicable, reimbursed such Lender for its increased costs and additional payments for which it is entitled to reimbursement under Section 2.8, as
applicable, of this Agreement through the date of such sale and assignment and (ii) Borrowers shall pay to Administrative Agent the $3,500 processing fee in 

  

 45 

 
respect of such assignment. In the event that a replaced Lender does not execute an Assignment Agreement pursuant to Section 12.6(a) within five
(5) Business Days after receipt by such replaced Lender of notice of replacement pursuant to this Section 12.6(c) and presentation to such replaced Lender of an Assignment Agreement evidencing an assignment pursuant to this
Section 12.6(c), such replaced Lender shall be deemed to have consented to the terms of such Assignment Agreement, and any such Assignment Agreement executed by Administrative Agent, the Replacement Lender and, to the extent required pursuant
to Section 12.6(a), Borrower, shall be effective for purposes of this Section 12.6(c) and Section 12.6(a). Upon any such assignment and payment, such replaced Lender shall no longer constitute a “Lender” for purposes hereof,
other than with respect to such rights and obligations that survive termination as set forth in Section 12.1. 
 (d) Credit Party
Assignments. No Credit Party may assign, delegate or otherwise transfer any of its rights or other obligations hereunder or under any other Financing Document without the prior written consent of Administrative Agent and each Lender. 

Section 12.7 Confidentiality. Administrative Agent and each Lender shall hold all non-public information regarding the Credit Parties and
their respective businesses identified as such by Borrowers and obtained by Administrative Agent or any Lender pursuant to the requirements hereof in accordance with such Person’s customary procedures for handling information of such nature,
except that disclosure of such information may be made (a) to their respective agents, employees, Subsidiaries, Affiliates, attorneys, auditors, professional consultants, rating agencies, insurance industry associations and portfolio management
services, (b) to prospective transferees or purchasers of any interest in the Loans, provided, however, that any such Persons shall have agreed to be bound by the provisions of this Section, (c) as required by Law, subpoena,
judicial order or similar order and in connection with any litigation, (d) as may be required in connection with the examination, audit or similar investigation of such Person, and (e) to a Person that is a trustee, investment advisor,
collateral manager, servicer, noteholder or secured party in a Securitization (as hereinafter defined) in connection with the administration, servicing and reporting on the assets serving as collateral for such Securitization. For the purposes of
this Section, “Securitization” shall mean a public or private offering by a Lender or any of its Affiliates or their respective successors and assigns, of securities which represent an interest in, or which are collateralized, in whole or
in part, by the Loans. Confidential information shall include only such information identified as such at the time provided to Administrative Agent or Lender, as the case may be, and shall not include information that either: (i) is in the
public domain, or becomes part of the public domain after disclosure to such Person through no fault of such Person, or (ii) is disclosed to such Person by a Person other than a Credit Party, provided, however, Administrative
Agent does not have actual knowledge that such Person is prohibited from disclosing such information. The obligations of Administrative Agent and Lenders under this Section shall supersede and replace the obligations of Administrative Agent and
Lenders under any confidentiality agreement in respect of this financing executed and delivered by Administrative Agent or any Lender prior to the date hereof. 
 Section 12.8 Waiver of Consequential and Other Damages. To the fullest extent permitted by applicable law, no Borrower shall assert, and each Borrower hereby waives, any claim against any Indemnitee (as
defined below), on any theory of liability, for special, indirect, consequential or punitive damages (as opposed to direct or actual damages) arising out of, in connection with, or as a result of this Agreement, any other Financing Document or any
agreement or instrument contemplated hereby or thereby, the transactions contemplated hereby or thereby, or the use of the proceeds thereof. No Indemnitee shall be liable for any damages arising from the use by unintended recipients of any
information or other materials distributed by it through telecommunications, electronic or other information transmission systems in connection with this Agreement or the other Financing Documents or the transactions contemplated hereby or thereby.

 Section 12.9 GOVERNING LAW; SUBMISSION TO JURISDICTION. THIS AGREEMENT, EACH NOTE AND EACH OTHER FINANCING DOCUMENT, AND ALL
MATTERS RELATING HERETO OR THERETO OR ARISING THEREFROM (WHETHER SOUNDING IN CONTRACT LAW, TORT LAW OR OTHERWISE), SHALL BE GOVERNED BY, AND SHALL BE CONSTRUED AND ENFORCED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF ILLINOIS, WITHOUT REGARD TO
CONFLICTS OF LAWS PRINCIPLES. EACH BORROWER HEREBY CONSENTS TO THE JURISDICTION OF ANY STATE OR FEDERAL COURT LOCATED WITHIN CHICAGO, STATE OF ILLINOIS AND IRREVOCABLY AGREES THAT, SUBJECT TO ADMINISTRATIVE AGENT’S ELECTION, ALL ACTIONS OR
PROCEEDINGS ARISING OUT OF OR RELATING TO THIS AGREEMENT OR THE OTHER FINANCING 

  

 46 

 
DOCUMENTS SHALL BE LITIGATED IN SUCH COURTS. EACH BORROWER EXPRESSLY SUBMITS AND CONSENTS TO THE JURISDICTION OF THE AFORESAID COURTS AND WAIVES ANY DEFENSE
OF FORUM NON CONVENIENS. EACH BORROWER HEREBY WAIVES PERSONAL SERVICE OF ANY AND ALL PROCESS AND AGREES THAT ALL SUCH SERVICE OF PROCESS MAY BE MADE UPON SUCH BORROWER BY CERTIFIED OR REGISTERED MAIL, RETURN RECEIPT REQUESTED, ADDRESSED TO SUCH
BORROWER AT THE ADDRESS SET FORTH IN THIS AGREEMENT AND SERVICE SO MADE SHALL BE COMPLETE TEN (10) DAYS AFTER THE SAME HAS BEEN POSTED. 
 Section 12.10 WAIVER OF JURY TRIAL. EACH BORROWER, ADMINISTRATIVE AGENT AND THE LENDERS HEREBY IRREVOCABLY WAIVES ANY AND ALL RIGHT TO TRIAL BY JURY IN ANY LEGAL ACTION OR PROCEEDING ARISING OUT OF OR RELATING TO THE FINANCING
DOCUMENTS OR THE TRANSACTIONS CONTEMPLATED THEREBY AND AGREES THAT ANY SUCH ACTION OR PROCEEDING SHALL BE TRIED BEFORE A COURT AND NOT BEFORE A JURY. EACH BORROWER, ADMINISTRATIVE AGENT AND EACH LENDER ACKNOWLEDGES THAT THIS WAIVER IS A MATERIAL
INDUCEMENT TO ENTER INTO A BUSINESS RELATIONSHIP, THAT EACH HAS RELIED ON THE WAIVER IN ENTERING INTO THIS AGREEMENT AND THE OTHER FINANCING DOCUMENTS, AND THAT EACH WILL CONTINUE TO RELY ON THIS WAIVER IN THEIR RELATED FUTURE DEALINGS. EACH
BORROWER, ADMINISTRATIVE AGENT AND EACH LENDER WARRANTS AND REPRESENTS THAT IT HAS HAD THE OPPORTUNITY OF REVIEWING THIS JURY WAIVER WITH LEGAL COUNSEL, AND THAT IT KNOWINGLY AND VOLUNTARILY WAIVES ITS JURY TRIAL RIGHTS. 
 Section 12.11 Publication; Advertisement. 
 (a) Publication. No Credit Party will directly or indirectly publish, disclose or otherwise use in any public disclosure, advertising material, promotional material, press release or interview, any reference to
the name, logo or any trademark of Merrill Lynch or any of its Affiliates or any reference to this Agreement or the financing evidenced hereby, in any case except (i) as required by Law, subpoena or judicial or similar order, in which case the
applicable Credit Party shall give Administrative Agent prior written notice of such publication or other disclosure, or (ii) with Merrill Lynch’s prior written consent. 
 (b) Advertisement. Each Lender and each Credit Party hereby authorizes Merrill Lynch to publish the name of such Lender and Credit Party, the
existence of the financing arrangements referenced under this Agreement, the primary purpose and/or structure of those arrangements, the amount of credit extended under each facility, the title and role of each party to this Agreement, and the total
amount of the financing evidenced hereby in any “tombstone”, comparable advertisement or press release which Merrill Lynch elects to submit for publication. In addition, each Lender and each Credit Party agrees that Merrill Lynch may
provide lending industry trade organizations with information necessary and customary for inclusion in league table measurements after the Closing Date. With respect to any of the foregoing, Merrill Lynch shall provide Borrowers with an opportunity
to review and confer with Merrill Lynch regarding the contents of any such tombstone, advertisement or information, as applicable, prior to its submission for publication and, following such review period, Merrill Lynch may, from time to time,
publish such information in any media form desired by Merrill Lynch, until such time that Borrowers shall have requested Merrill Lynch cease any such further publication. 
 Section 12.12 Counterparts; Integration. This Agreement and the other Financing Documents may be signed in any number of counterparts, each of which shall be an original, with the same effect as if the
signatures thereto and hereto were upon the same instrument. Signatures by facsimile or by email delivery of an electronic version of an executed signature page shall bind the parties hereto. This Agreement and the other Financing Documents
constitute the entire agreement and understanding among the parties hereto and supersede any and all prior agreements and understandings, oral or written, relating to the subject matter hereof. 
 Section 12.13 No Strict Construction. The parties hereto have participated jointly in the negotiation and drafting of this Agreement. In the
event an ambiguity or question of intent or interpretation arises, this Agreement shall be construed as if drafted jointly by the parties hereto and no presumption or burden of proof shall arise favoring or disfavoring any party by virtue of the
authorship of any provisions of this Agreement. 
  

 47 

 Section 12.14 Lender Approvals. Unless expressly provided herein to the contrary, any
approval, consent, waiver or satisfaction of Administrative Agent or Lenders with respect to any matter that is the subject of this Agreement, the other Financing Documents may be granted or withheld by Administrative Agent and Lenders in their sole
and absolute discretion and credit judgment. 
 Section 12.15 Expenses; Indemnity 
 (a) Borrowers agree to pay all reasonable legal, audit and appraisal fees and all other reasonable out-of-pocket charges and expenses incurred by
Administrative Agent and Lenders (including the fees and expenses of Administrative Agent’s counsel, advisors and consultants) in connection with the negotiation, preparation, legal review and execution of each of the Financing Documents,
including but not limited to UCC and judgment lien searches and UCC filings and fees for post-closing UCC and judgment lien searches. In addition, Borrowers shall pay all such fees and expenses associated with any amendments, modifications and
terminations to the Financing Documents following closing. If Administrative Agent or any Lender uses in-house counsel for any of these purposes, Borrowers further agree that the Obligations include reasonable charges for such work commensurate with
the fees that would otherwise be charged by outside legal counsel selected by Administrative Agent or such Lender for the work performed. 
 (b) Borrowers agree to pay all out-of-pocket charges and expenses incurred by Administrative Agent (including the fees and expenses of Administrative Agent’s counsel, advisers and consultants) in connection with the administration of
this Agreement and the other Financing Documents and the credit facilities provided hereunder and thereunder, the administration, enforcement, protection or preservation of any right or claim of Administrative Agent, the termination of this
Agreement, the termination of any Liens of Administrative Agent on the Collateral, or the collection of any amounts due under the Financing Documents, including any such charges and expenses incurred in connection with any “work-out” or
with any proceeding under the Bankruptcy Code with respect to any Credit Party. If Administrative Agent uses in-house counsel for any of these purposes (i.e., for any task in connection with the enforcement, protection or preservation of any right
or claim of Administrative Agent and Lenders and the collection of any amounts due under the Financing Documents or in connection with any other purpose mentioned in the foregoing sentence), Borrowers further agree that the Obligations include
reasonable charges for such work commensurate with the fees that would otherwise be charged by outside legal counsel selected by Administrative Agent for the work performed. 
 (c) Borrowers hereby indemnify and agree to defend (with counsel acceptable to Administrative Agent) and hold harmless Administrative Agent, each Lender,
and their respective shareholders, directors, partners, officers, agents and employees (collectively in the singular, “Indemnitee”) from and against any liability, loss, cost, expense (including reasonable attorneys’ fees and
expenses for both in-house and outside counsel), claim, damage, suit, action or proceeding ever suffered or incurred by any Indemnitee or in which an Indemnitee may ever be or become involved (whether as a party, witness or otherwise)
(a) arising from any Credit Party’s failure to observe, perform or discharge any of its covenants, obligations, agreements or duties under the Financing Documents, (b) arising from the breach of any of the representations or
warranties contained in any Financing Document, (c) arising by reason of this Agreement, the other Financing Documents or the transactions contemplated hereby or thereby, or (d) relating to claims of any Person with respect to the
Collateral; provided, however, Borrowers shall not be liable under this Section 12.15(c) to the extent such loss is solely related to Indemnitee’s gross negligence or willful misconduct. 
 (d) Notwithstanding any contrary provision in this Agreement, the obligations of Borrowers under this Section shall survive the payment in full of the
Obligations and the termination of this Agreement. NO INDEMNITEE SHALL BE RESPONSIBLE OR LIABLE TO THE BORROWERS OR TO ANY OTHER PARTY TO ANY FINANCING DOCUMENT, ANY SUCCESSOR, ASSIGNEE OR THIRD PARTY BENEFICIARY OR ANY OTHER PERSON ASSERTING CLAIMS
DERIVATIVELY THROUGH SUCH PARTY, FOR INDIRECT, PUNITIVE, EXEMPLARY OR CONSEQUENTIAL DAMAGES WHICH MAY BE ALLEGED AS A RESULT OF CREDIT HAVING BEEN EXTENDED, SUSPENDED OR TERMINATED UNDER THIS AGREEMENT OR ANY OTHER FINANCING DOCUMENT OR AS A RESULT
OF ANY OTHER TRANSACTION CONTEMPLATED HEREUNDER OR THEREUNDER. 
  

 48 

 Section 12.16 Reinstatement. This Agreement shall remain in full force and effect and
continue to be effective should any petition or other proceeding be filed by or against any Credit Party for liquidation or reorganization, should any Credit Party become insolvent or make an assignment for the benefit of any creditor or creditors
or should an interim receiver, receiver, receiver and manger or trustee be appointed for all or any significant part of any Credit Party’s assets, and shall continue to be effective or to be reinstated, as the case may be, if at any time
payment and performance of the Obligations, or any part thereof, is, pursuant to applicable law, rescinded or reduced in amount, or must otherwise be restored or returned by any obligee of the Obligations, whether as a fraudulent conveyance,
preference or otherwise, all as though such payment or performance had not been made. In the event that any payment, or any part thereof, is rescinded, reduced, restored or returned, the Obligations shall be reinstated and deemed reduced only by
such amount paid and not so rescinded, reduced, restored or returned. 
 [SIGNATURES APPEAR ON FOLLOWING PAGES] 

  

 49 

 IN WITNESS WHEREOF, intending to be legally bound, and intending that this document constitute an
instrument executed and delivered under seal, the parties hereto have caused this Agreement to be duly executed under seal by their respective authorized officers as of the day and year first above written. 
  

			
	BORROWER:
	
	 TARGANTA THERAPEUTICS CORPORATION,
 a Delaware corporation

		
	By:	 	 /s/ George A. Eldridge

	Name:	 	George A. Eldridge
	Title:	 	Treasurer and Assistant Secretary

 Address: 
 222 3rd Street, Suite 2300 
 Cambridge, Massachusetts 02142 
 Attn: George Eldridge 
 Facsimile:
(617) 577-9021 
 E-Mail: geldrige@targanta.com 
 [Signature Page to Credit and Security Agreement] 

			
	AGENT:
	
	 MERRILL LYNCH CAPITAL,
 a division of Merrill Lynch Business Financial Services Inc.,
 a Delaware corporation, as
Administrative Agent

		
	By:	 	 /s/ Chris York

	Name:	 	Chris York
	Title:	 	Vice President

 Address: 
 222 N. LaSalle Street, 16th Floor 
 Chicago, Illinois 60601 
 Attn: Account Manager for MLC-HCF Targanta Therapeutics Corporation transaction 
 Facsimile: (866) 231-8408 
 E Mail:
MLC_HCF_ABL1@ml.com 
 With copies to: 
 Merrill Lynch Capital 
 222 N. LaSalle Street, 16th Floor 
 Chicago, Illinois 60601 

Attn: Group Senior Transaction Attorney, Healthcare Finance 
 Facsimile Number: (312) 499-3245 
 Merrill Lynch Capital 
 7700 Wisconsin Ave., Suite 400 
 Bethesda,
Maryland 20814 
 Attn: Group Senior Transaction Attorney, Healthcare Finance 
 Facsimile Number: (866) 341-9053 
 Payment Account Designation: 
 LaSalle Bank 
 200 West Monroe 
 Chicago, IL 60606 
 ABA #: 071000505 
 Account Name: MLBFS
Healthcare Finance 
 Account #: 5800395088 
 Attention: Targanta Therapeutics Corporation 
 [Signature Page to Credit and Security Agreement] 

			
	LENDERS:
	
	 MERRILL LYNCH CAPITAL,
 a division of Merrill Lynch Business Financial Services Inc.,
 a Delaware corporation, as
Lender

			
		
	By:	 	 /s/ Chris York

	Name:	 	Chris York
	Title:	 	Vice President

 Address: 
 222 N. LaSalle Street, 16th Floor 
 Chicago, Illinois 60601 
 Attn: Account Manager for MLC-HCF Targanta Therapeutics Corporation transaction 
 Facsimile: (866) 231-8408 
 E-Mail:
MLC_HCF_ABL1@ml.com 
 With copies to: 
 Merrill Lynch Capital 
 222 N. LaSalle Street, 16th Floor 
 Chicago, Illinois 60601 

Attn: Group Senior Transaction Attorney, Healthcare Finance 
 Facsimile Number: (312) 499-3245 
 Merrill Lynch Capital 
 7700 Wisconsin Ave., Suite 400 
 Bethesda,
Maryland 20814 
 Attn: Group Senior Transaction Attorney, Healthcare Finance 
 Facsimile Number: (866) 341-9053 
 [Signature Page to Credit and Security Agreement] 

			
	OXFORD FINANCE CORPORATION,
	a Delaware corporation, as Lender
		
	By:	 	 /s/ Timothy A. Lex

	Name:	 	Timothy A. Lex
	Title:	 	Chief Operating Officer

 Address: 
 Oxford Finance Corporation 
 133 North Fairfax Street 
 Alexandria, Virginia 22314 
 Attn: Tim Lex

 Facsimile: (703) 519-4910 
 E-Mail: tlex@oxfordfinance.com 
  

 [Signature Page to Credit and Security Agreement] 

			
	BLUECREST CAPITAL FINANCE, L.P.
	By: BlueCrest Capital Finance GP, LLC, its General Partner,
	as Lender
		
	By:	 	 /s/ Mark King

	Name:	 	Mark King
	Title:	 	Managing Director

 Address: 
 BlueCrest Capital Finance, L.P. 
 225 West Washington Street, Suite 200 
 Chicago, IL 60606 
 Attn: Mark King 
 Facsimile: (312) 443-0126 
 E-Mail: mking@us.bluecrestcapital.com 
 [Signature Page to Pharma Rider]

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