Document:

SUNESIS
      PHARMACEUTICALS, INC.

     

    2008
      Executive Bonus Program

     

    
      	I.	
              Overview

            

    

     

    The
      2008
      Executive Bonus Program (the “Program”)
      of
      Sunesis Pharmaceuticals, Inc. (the “Company”),
      effective as of August 6, 2008, is designed to motivate, retain and reward
      eligible executive-level employees through a combination of corporate and
      individual performance-based incentive compensation components for performance
      during the second half of 2008 (the “First
      Performance Period”)
      and
      the first half of 2009 (the “Second
      Performance Period”
and
      collectively with the First Performance Period, the “Performance
      Period”).
      The
      Program supersedes and replaces in its entirety, as to the Eligible Executives
      (defined below), the Amended and Restated 2008 Bonus Program that was originally
      adopted by the Company’s Board of Directors on March 5, 2008 and that was
      amended by the Compensation Committee of the Company’s Board of Directors (the
“Committee”)
      on
      June 3, 2008. 

    

    “Eligible
      Executives”
are
      the
      Company’s Vice President level employees and above who have been notified in
      writing of their eligibility to participate in the Program and who timely sign
      and return their “Bonus
      Opportunity Notice”
(in
      substantially the form attached hereto). The Program is administered by the
      Committee and the Company’s Outside Directors (defined below), and any
      determination made by the Committee and/or the Outside Directors in good faith
      shall be final and binding on all parties. 

     

    Under
      the
      Program, each Eligible Executive receives the opportunity to earn an aggregate
      bonus (the “Bonus
      Opportunity”)
      based
      on (i) the level of achievement by the Company of certain corporate objectives
      (the “Corporate
      Objectives”)
      in
      each of the First Performance Period and the Second Performance Period, and
      (ii)
      the Eligible Executive’s level of achievement of certain individual performance
      objectives, which may take into consideration certain department, group and/or
      team objectives applicable to such Eligible Executive (the “Individual
      Objectives”)
      in
      each of the First Performance Period and the Second Performance Period.

     

    
      	II.	
              Program
                Objectives

            

    

     

    The
      Program is intended to encourage and incentivize individual and group
      contributions and efforts, including:

     

    
      	 	
              ·

            	
              the
                achievement of Corporate Objectives during the Performance Period;
                

            

    

    
      	 	
              ·

            	
              the
                achievement of Individual Objectives during the Performance Period;
                and

            

    

    
      	 	
              ·

            	
              the
                achievement of increased value for our shareholders during and following
                the Performance Period.

            

    

     

    
      	III.	
              Determination
                of the Performance Period
                Objectives

            

    

     

    The
      Corporate Objectives for the First Performance Period and Second Performance
      Period, respectively, shall be approved by the Committee, with input from
      management, and generally relate to the achievement of certain clinical
      development, business development, financial, business and similar
      milestones.  Each Corporate Objective shall be assigned a relative
      weighting from the Committee, reflecting its importance to the achievement
      of
      the Company’s key results for the First Performance Period and Second
      Performance Period, respectively.

     

    
      
        Approved
          August 6, 2008

         

      

      
        1

        
          

        

      

      
         

      

    

     

    The
      Individual Objectives for the First Performance Period and Second Performance
      Period, respectively, shall be set as follows:

     

    
      	 	
              ·

            	
              For
                the Chief Executive Officer and the Executive Chairman, the Individual
                Objectives shall be set by the Committee, subject to approval by
                the
                Company’s “outside directors” (as such term is defined under Section
                162(m) of the Internal Revenue Code of 1986, as amended (the “Outside
                Directors”));

            

    

    
      	 	
              ·

            	
              For
                the Eligible Executives who are executive officers (as that term
                is
                defined under Section 16 of the Securities Exchange Act of 1934,
                as
                amended, and Rule 16a-1 thereunder), other than the Chief Executive
                Officer and the Executive Chairman (collectively, the “Section
                16
                Participants”),
                the Individual Objectives shall be set by the Committee based upon
                recommendations made by the Chief Executive Officer;
                and

            

    

    
      	 	
              ·

            	
              For
                all other Eligible Executives, the Individual Objectives shall be
                set by
                the Chief Executive Officer. 

            

    

     

    The
      Bonus
      Opportunity Notice sent to each Eligible Executive will state the Corporate
      Objectives and that employee’s Individual Objectives for the Performance
      Period.

     

    
      	IV.	
              Size
                of the Bonus Opportunity

            

    

     

    For
      the
      Performance Period, the target Bonus Opportunity (the “Bonus
      Target”)
      for
      each Eligible Executive, expressed as a specified percentage of his or her
      2008
      annual base salary and based upon the position such Eligible Executive holds
      with the Company, is determined as follows:

     

    
      	 	
              ·

            	
              For
                the Chief Executive Officer and the Executive Chairman, the Bonus
                Target
                shall be set by the Committee, subject to approval by the Outside
                Directors; and 

            

    

    
      	 	
              ·

            	
              For
                all other Eligible Executives, the Bonus Target shall be set by the
                Committee based upon recommendations made by the Chief Executive
                Officer.

            

    

     

    The
      Bonus
      Target for the Performance Period shall range from 50% to 80% of an Eligible
      Executive’s 2008 annual base salary. The Bonus Target for the Performance Period
      shall be weighted 50% to the First Performance Period and 50% to the Second
      Performance Period (each such eligible installment, the “Semi-Annual
      Target”).
      

     

    
      	V.	
              Determination
                of Bonus

            

    

     

    A
      determination of the level of achievement of the Corporate Objectives and the
      Individual Objectives and of the Actual Bonus Opportunity (as defined below)
      will be made as set forth below (a) for the First Performance Period in the
      first quarter of 2009 and (b) for the Second Performance Period in the third
      quarter of 2009. 

     

    
      
        Approved
          August 6, 2008

         

      

      
        2

        
          

        

      

      
         

      

    

     

    Determination
      of Level of Achievement of Corporate Objectives

     

    The
      date
      when the Committee makes a determination as to the achievement of the Corporate
      Objectives is referred to as the “Review
      Date”.
      On the
      applicable Review Date, the Committee shall determine, after receiving and
      considering recommendations from management, the degree to which the Corporate
      Objectives have been met for the First Performance Period and the Second
      Performance Period, respectively, expressed as a percentage of Corporate
      Objectives achieved (the “Corporate
      Achievement Percentage”),
      taking into consideration the weighting assigned to each Corporate
      Objective.  The Corporate Achievement Percentage is not capped at 100%.

    

    Adjustment
      of Bonus Targets based on Level of Achievement of Corporate
      Objectives

     

    The
      Committee will then on such Review Date adjust each Eligible Executive’s
      Semi-Annual Target for the applicable half of the Performance Period so that
      it
      equals the product of (i) the Corporate Achievement Percentage and (ii) the
      Semi-Annual Target. For example, if the Committee determines that only 80%
      of
      the Corporate Objectives have been achieved in the First Performance Period,
      the
      Corporate Achievement Percentage is 80%, and each Eligible Executive’s
      Semi-Annual Target for the First Performance Period shall be decreased by 20%
      (in other words, if an Eligible Executive has a Semi-Annual Target of 30%,
      that
      target will be adjusted to be 24%, or 80% of 30%, for the First Performance
      Period.)  Such adjusted Semi-Annual Target is referred to as the
“Adjusted
      Bonus Target.”

     

    Determination
      of Size and Form of Individual Bonuses 

    Each
      Eligible Executive’s level of achievement of his or her Individual Objectives
      for the applicable half of the Performance Period, as well as his or her
      contribution to the achievement of the Corporate Objectives for the applicable
      half of the Performance Period, shall be determined as follows: 

    

    
      	 	
              ·

            	
              For
                the Chief Executive Officer and the Executive Chairman, by the Committee,
                subject to approval by the Outside
                Directors;

            

    

    
      	 	
              ·

            	
              For
                the Section 16 Participants, by the Committee based upon recommendations
                made by the Chief Executive Officer;
                and

            

    

    
      	 	
              ·

            	
              For
                all other Eligible Executives, by the Chief Executive Officer.
                

            

    

     

    Following
      the Review Date and after assessing each Eligible Executive’s level of
      achievement as described above, the Committee will determine the value of the
      Eligible Executive’s actual Bonus Opportunity for the applicable half of the
      Performance Period as a percentage of such Eligible Executive’s Adjusted Target
      Bonus (the “Actual
      Bonus Opportunity”).
      In
      determining the Actual Bonus Opportunity, the Committee may also consider,
      in
      addition to individual performance, business factors including but not limited
      to (i) the Company’s available cash, (ii) the Company’s stock price, (iii) the
      Company’s available stock plan share reserves, (iv) general business conditions,
      (v) the Company’s achievement of publicly announced targets, clinical
      milestones, and/or strategic goals, (vi) cross-functional teamwork and
      collaboration, and (vii) unforeseen changes in the economy and/or geopolitical
      climate. In addition, the Committee, in its sole discretion, will determine
      whether to pay some or all of the Actual Bonus Opportunity in cash or in
      restricted stock awards, restricted stock units or stock options under the
      Company’s 2005 Equity Incentive Award Plan (collectively, the “Equity
      Awards”)
      and
      the Committee may require such Equity Awards to be subject to time-based vesting
      following the Determination Date (as defined below); provided, however, that
      at
      least 50% of the value of any Actual Bonus Opportunity finally determined by
      the
      Committee will be paid in cash.

     

    
      
        Approved
          August 6, 2008

         

      

      
        3

        
          

        

      

      
         

      

    

     

    In
      the
      case of the Actual Bonus Opportunity determined for the Eligible Executives
      other than the Chief Executive Officer and the Executive Chairman, the Committee
      shall consider the recommendations made by the Chief Executive Officer. In
      the
      case of the Actual Bonus Opportunity determined for the Chief Executive Officer
      and the Executive Chairman, the Committee’s determination is subject to the
      approval by the Outside Directors. 

    

    The
      dates
      on which the Committee (or the Outside Directors, as applicable) makes such
      determinations (or approval, as applicable) are the “Determination
      Dates”.
      An
      Eligible Executive must remain employed by the Company through the relevant
      Determination Date in order to earn an Actual Bonus Opportunity, subject to
      such
      additional vesting conditions that may apply to Equity Awards issued in
      accordance with this Program.  For the avoidance of doubt, no Eligible
      Executive has a legally binding right to any amounts under this Program prior
      to
      the Determination Date. The value of any Equity Awards issued to satisfy the
      Actual Bonus Opportunity will be determined by the Committee in its sole
      discretion.

    

    Except
      as
      expressly set forth above with respect to approval required from the Outside
      Directors of Actual Bonus Opportunities for the Chief Executive Officer and
      the
      Executive Chairman, the Committee has final authority with respect to the
      determination of whether to award any Actual Bonus Opportunity and whether
      such
      Actual Bonus Opportunity will be subject to additional time based vesting
      following the Determination Date. 

     

    
      	VI.	
              Payment
                Dates

            

    

    

    Following
      the Determination Date, the Committee (or the Outside Directors, as applicable)
      will determine the date(s) on which any Actual Bonus Opportunity will be paid
      and/or granted, as applicable, and such dates shall be referred to as
“Payment
      Dates”.
      In all
      cases, a Payment Date will be not later than the fifteenth day of the third
      month following the month in which the relevant Determination Date occurs.
      The
      Company’s intention is that all payments and benefits under the Program shall be
      made in a manner that satisfies, to the greatest extent possible, the exemption
      from the application of Section 409A of the Internal Revenue Code of 1986,
      as
      amended (the “Code”)
      provided under Treasury Regulations 1.409A-1(b)(4). It is intended that each
      installment of the payments and benefits provided for in this Program is a
      separate “payment” for purposes of Treasury Regulation Section
      1.409A-2(b)(2)(i).

     

    
      	VII.	
              Miscellaneous
                Provisions

            

    

     

    Participation
      in the Program shall not alter in any way the at will nature of the Company’s
      employment of an Eligible Executive, and such employment may be terminated
      at
      any time for any reason, with or without cause and with or without prior
      notice.  Nothing in this Program shall be construed to be a guarantee that
      any Eligible Executive will receive all or part of a Bonus Opportunity or Actual
      Bonus Opportunity or to imply a contract between the Company and any Eligible
      Executive. 

     

    This
      Program supersedes and replaces all prior cash incentive and bonus plans of
      the
      Company with respect to Eligible Executives.  The Company may amend or
      terminate this Program at any time, with or without notice and with or without
      the Eligible Executive’s consent. The Committee may likewise terminate an
      individual’s participation in the Program at any time, with or without notice or
      the individual’s consent.  Further, the Company may modify the Corporate
      Objectives, the Individual Objectives, the Bonus Opportunities, the Bonus
      Targets and the Actual Bonus Opportunities at any time.  

     

    The
      Program shall be interpreted in accordance with California law without reference
      to conflicts of law principles.

    

      
        
          Approved
            August 6, 2008

           

        

        
          4

          
            

          

        

        
           

        

      

    

     

    BONUS
      OPPORTUNITY NOTICE

    

    I
      hereby
      accept the designation as an Eligible Executive in the Sunesis Pharmaceuticals,
      Inc. 2008 Executive Bonus Program (the “Program”).
      I
      have read the Program and understand and agree to its terms. I acknowledge
      and
      agree that I have no further rights under the Sunesis Pharmaceuticals, Inc.
      Amended and Restated 2008 Bonus Program that was originally adopted by the
      Company’s Board of Directors on March 5, 2008 and that was amended by the
      Compensation Committee of the Company’s Board of Directors on June 3, 2008.

     

    I
      understand that my Bonus Target is [____]% of my 2008 annual base salary, and
      therefore my Semi-Annual Target is [____]% of my 2008 annual base salary. I
      hereby acknowledge and agree that for purposes of my Executive Severance
      Benefits Agreement with the Company, dated [  ],
      that
      the “target annual bonus” referenced in Section 3.2(b) thereof shall constitute
      and shall mean for purposes of such agreement my Semi-Annual Target under this
      Program and any contrary language in such agreement is hereby
      superceded.

     

    I
      understand that the Corporate Objectives for the First Performance Period are
      as
      follows:

     

    
      	 	
              ·

            	
              _________

            

    

     

    
      	 	
              ·

            	
              _________

            

    

     

    I
      understand that the Corporate Objectives for the Second Performance Period
      are
      as follows: 

     

    
      	 	
              ·

            	
              _________

            

    

     

    
      	 	
              ·

            	
              _________

            

    

     

    I
      understand that my Individual Objectives for the First Performance Period are
      as
      follows:

     

    
      	 	
              ·

            	
              _________

            

    

     

    
      	 	
              ·

            	
              _________

            

    

     

    I
      understand that my Individual Objectives for the Second Performance Period
      are
      as follows:

     

    
      	 	
              ·

            	
              _________

            

    

     

    
      	 	
              ·

            	
              _________

            

    

     

    Acknowledged
      & Agreed:

     

    ___________________________

    [Name]

    ___________________________

    Date: 

     

    
      
        Approved
          August 6, 2008

         

      

      
        5SUNESIS
      PHARMACEUTICALS, INC.

     

    STOCK
      OPTION GRANT NOTICE AND STOCK OPTION AGREEMENT

    UNDER
      THE 2006
      EMPLOYMENT COMMENCEMENT INCENTIVE PLAN

    

    Sunesis
      Pharmaceuticals, Inc. (the “Company”),
      pursuant to its 2006 Employment Commencement Incentive Plan (the “Plan”)
      hereby
      grants to the Optionee listed below (“Optionee”),
      an
      option to purchase the number of shares of the Company’s Stock set forth below.
      This option is subject to all of the terms and conditions as set forth herein
      and in the Stock Option Agreement and the Plan, each of which are attached
      hereto and incorporated herein by reference. Unless otherwise defined herein,
      the terms defined in the Plan shall have the same defined meanings in this
      Stock
      Option Agreement.

     

    
      	
              Optionee:

            	 	 
	 	 	 
	
              Date
                of Stock Option Agreement:

            	 	 
	 	 	 
	
              Grant
                Date:

            	 	 
	 	 	 
	
              Vesting
                Commencement Date: 

            	 	 
	 	 	 
	
              Exercise
                Price per Share:

            	 	
              $
                

            
	 	 	 
	
              Total
                Number of Shares Granted:

            	 	 
	 	 	 
	
              Total
                Exercise Price:

            	 	
              $

            
	 	 	 
	
              Expiration
                Date:

            	 	 

    

    

    
      	Type
              of Option:	
              This
                Option is a Non-Qualified Stock
                Option

            

    

    

    
      	Vesting
              Schedule:	
              [Twenty-five
                percent (25%) of the shares subject to the Option shall vest twelve
                months
                after the Vesting Commencement Date, and 1/48th
                of
                the shares subject to the Option shall vest each month thereafter
                on the
                same day of the month as the Vesting Commencement Date, subject to
                the
                Optionee’s continued service with the Company as provided in the Stock
                Option Agreement.]

            

    

     

    By
      his or
      her signature and the Company's signature below, Optionee agrees to be bound
      by
      the terms and conditions of the Plan and the Stock Option Agreement attached
      hereto. Optionee has reviewed the Stock Option Agreement and the Plan in their
      entirety, has had an opportunity to obtain the advice of counsel prior to
      executing this option and fully understands all provisions of the Grant Notice,
      the Stock Option Agreement and the Plan. Optionee agrees that Optionee has
      not
      been previously employed in any capacity by the Company or a Subsidiary, or
      if
      previously employed, has had a bona-fide period of non-employment, and that
      the
      grant of this Option is an inducement material to Optionee’s agreement to enter
      into employment with the Company or Subsidiary. Optionee hereby agrees to accept
      as binding, conclusive and final all decisions or interpretations of the
      administrator of the Plan upon any questions arising under the Plan or this
      option. Optionee further agrees to notify the Company upon any change in the
      residence address indicated below.

     

    
      	
              SUNESIS
                PHARMACEUTICALS, INC.

            	
              OPTIONEE:

            
	 	 
	
              By:______________________________

            	
              By:______________________________

            
	
              Print
                Name: 

            	
              Print
                Name: 

            
	
              Title:
                 

            	 
	
              Address:
                

            	
              Address: 

            

    

    

    
      
         

      

      
        
          GRANT
            NOTICE PAGE 1

        

        
          

        

      

      
         

      

    

    SUNESIS
      PHARMACEUTICALS, INC.

    2006
      EMPLOYMENT COMMENCEMENT INCENTIVE PLAN

     

    STOCK
      OPTION AGREEMENT

     

    Pursuant
      to the Stock Option Grant Notice (“Grant
      Notice”)
      to
      which this Stock Option Agreement (this “Agreement”)
      is
      attached, Sunesis Pharmaceuticals, Inc. (the “Company”)
      has
      granted to the Optionee an option under the Company’s 2006 Employment
      Commencement Incentive Plan (the “Plan”)
      to
      purchase the number of shares of Stock indicated in the Grant Notice at the
      exercise price indicated in the Grant Notice. Unless otherwise defined herein,
      the terms defined in the Plan shall have the same defined meanings in this
      Stock
      Option Agreement.

     

    ARTICLE
      I

    DEFINITIONS;
      INCORPORATION OF TERMS

     

    1.1 General.
      Wherever the following terms are used in this Agreement they shall have the
      meanings specified below, unless the context clearly indicates otherwise.
      Capitalized terms not specifically defined herein shall have the meanings
      specified in the Plan.

     

    1.2 Incorporation
      of Terms of Plan.
      The
      Option is subject to the terms and conditions of the Plan which are incorporated
      herein by reference.

     

    ARTICLE
      II

    GRANT
      OF OPTION

     

    2.1 Grant
      of Option.
      In
      consideration of the Optionee’s agreement to commence and remain in the employ
      of the Company or its Subsidiaries and for other good and valuable
      consideration, effective as of the Grant Date set forth in the Grant Notice
      (the
“Grant
      Date”),
      the
      Company irrevocably grants to the Optionee the Option to purchase any part
      or
      all of an aggregate of the number of shares of Stock set forth in the Grant
      Notice, upon the terms and conditions set forth in this Agreement. The Option
      shall be a Non-Qualified Stock Option.

     

    2.2 Purchase
      Price.
      The
      purchase price of the shares of Stock subject to the Option per share shall
      be
      as set forth in the Grant Notice, without commission or other charge;
provided,
      however,
      that the
      exercise price shall not be less than the par value of a share of Stock, unless
      otherwise permitted by applicable law.

     

    2.3 Consideration
      to the Company.
      In
      consideration of the granting of the Option by the Company, the Optionee agrees
      to render faithful and efficient services to the Company or any Subsidiary,
      with
      such duties and responsibilities as the Company shall from time to time
      prescribe. Nothing in the Plan or this Agreement shall confer upon the Optionee
      any right to continue in the employ of the Company or any Subsidiary or shall
      interfere with or restrict in any way the rights of the Company and its
      Subsidiaries, which are hereby expressly reserved, to discharge the Optionee
      at
      any time for any reason whatsoever, with or without cause.

     

    
      
         

      

      
        
          STOCK
            OPTION AGREEMENT PAGE  1

        

        
          

        

      

      
         

      

    

     

    ARTICLE
      III

    PERIOD
      OF EXERCISABILITY

     

    3.1 Commencement
      of Exercisability.

     

    (a) Subject
      to Sections 3.3 and 5.10, the Option shall become exercisable in such amounts
      and at such times as are set forth in the Grant Notice.

     

    (b) No
      portion of the Option which has not become exercisable at Termination of Service
      (as defined in Section 3.3 below) shall thereafter become exercisable, except
      as
      may be otherwise provided by the Committee or as set forth in a written
      agreement between the Company and the Optionee.

     

    3.2 Duration
      of Exercisability.
      The
      installments provided for in Section 3.1(a) are cumulative. Each such
      installment which becomes exercisable pursuant to Section 3.1 shall remain
      exercisable until it becomes unexercisable under Section 3.3.

     

    3.3 Expiration
      of Option.
      The
      Option may not be exercised to any extent by anyone after the first to occur
      of
      the following events:

     

    (a) The
      expiration of ten years from the Grant Date; or

     

    (b) The
      expiration of three months following the date of the Optionee’s Termination of
      Service, unless such Termination of Service occurs by reason of the Optionee’s
      death or Disability or as set forth in a written agreement with the Company;
      or

     

    (c) The
      expiration of twelve months following
      the date of the Optionee’s Termination of Service by reason of the Optionee’s
      Disability; or

     

    (d)  The
      expiration of eighteen months following
      the date of the Optionee’s Termination of Service by reason of the Optionee’s
      death. 

     

    (e) For
      purposes of this Agreement, “Termination
      of Service”
means
      the time when the employment relationship between the Optionee and the Company
      or any Subsidiary is terminated for any reason, with or without cause,
      including, but not by way of limitation, a termination by resignation,
      discharge, death or Disability; but excluding (a) a termination where there
      is a
      simultaneous reemployment or continuing employment of the Optionee by the
      Company or any Subsidiary or a parent corporation thereof (within the meaning
      of
      Section 422 of the Code), (b) at the discretion of the Committee, a termination
      which results in a temporary severance of the employee-employer relationship,
      and (c) at the discretion of the Committee, a termination which is followed
      by
      the simultaneous establishment of a consulting relationship by the Company
      or a
      Subsidiary with the former Employee. The Committee, in its absolute discretion,
      shall determine the effect of all matters and questions relating to Termination
      of Service for the purposes of this Agreement, and all questions of whether
      particular leaves of absence for Optionees constitute Terminations of Service.
      Notwithstanding any other provision of the Plan or this Agreement, the Company
      or any Subsidiary has an absolute and unrestricted right to terminate the
      Optionee’s employment and/or consultancy at any time for any reason whatsoever,
      with or without cause.

    
       

      
        
           

        

        
          
            STOCK
              OPTION AGREEMENT PAGE  2

          

          
            

          

        

        
           

        

      

       

    

    ARTICLE
      IV

    EXERCISE
      OF OPTION

     

    4.1 Person
      Eligible to Exercise.
      Except
      as provided in Sections 5.2(b) and 5.2(c), during the lifetime of the Optionee,
      only the Optionee may exercise the Option or any portion thereof. After the
      death of the Optionee, any exercisable portion of the Option may, prior to
      the
      time when the Option becomes unexercisable under Section 3.3, be exercised
      by the Optionee’s beneficiary designated in accordance with Section 9.4 of the
      Plan. If no beneficiary has been designated or survives the Optionee, the Option
      may be exercised by the person entitled to such exercise pursuant to the
      Optionee’s will or the laws of descent and distribution.

     

    4.2 Partial
      Exercise.
      Any
      exercisable portion of the Option or the entire Option, if then wholly
      exercisable, may be exercised in whole or in part at any time prior to the
      time
      when the Option or portion thereof becomes unexercisable under
      Section 3.3.

     

    4.3 Manner
      of Exercise.
      The
      Option, or any exercisable portion thereof, may be exercised solely by delivery
      to the Secretary of the Company or the Secretary’s office of all of the
      following prior to the time when the Option or such portion thereof becomes
      unexercisable under Section 3.3:

     

    (a) An
      Exercise Notice in writing signed by the Optionee or the other person then
      entitled to exercise the Option or portion thereof, stating that the Option
      or
      portion thereof is thereby exercised, such notice complying with all applicable
      rules established by the Committee. Such notice shall be substantially in the
      form attached as Exhibit
      A
      (or such
      other form as is prescribed by the Committee); and

     

    (b) (i) Full
      payment (in cash or by check) for the shares with respect to which the Option
      or
      portion thereof is exercised, to the extent permitted under applicable laws;
      or

     

      (ii) To
      the
      extent permitted under applicable laws, through the delivery of a notice that
      the Optionee has placed a market sell order with a broker with respect to shares
      of Stock then issuable upon exercise of the Option, and that the broker has
      been
      directed to pay a sufficient portion of the net proceeds of the sale to the
      Company in satisfaction of the Option exercise price, provided,
      that
      payment of such proceeds is made to the Company upon settlement of such sale;
      or

     

    (iii) With
      the
      consent of the Committee, any combination of the consideration provided in
      the
      foregoing subparagraphs (i) and (ii); and

     

    (c) A
      bona
      fide written representation and agreement, in such form as is prescribed by
      the
      Committee, signed by the Optionee or other person then entitled to exercise
      such
      Option or portion thereof, stating that the shares of Stock are being acquired
      for the Optionee’s own account, for investment and without any present intention
      of distributing or reselling said shares or any of them except as may be
      permitted under the Securities Act of 1933, as amended (the “Securities
      Act”),
      and
      then applicable rules and regulations thereunder, and that the Optionee or
      other
      person then entitled to exercise such Option or portion thereof will indemnify
      the Company against and hold it free and harmless from any loss, damage, expense
      or liability resulting to the Company if any sale or distribution of the shares
      by such person is contrary to the representation and agreement referred to
      above.  The Committee may, in its absolute discretion, take whatever
      additional actions it deems appropriate to ensure the observance and performance
      of such representation and agreement and to effect compliance with the
      Securities Act and any other federal or state securities laws or regulations.
      Without limiting the generality of the foregoing, the Committee may require
      an
      opinion of counsel acceptable to it to the effect that any subsequent transfer
      of shares acquired on an Option exercise does not violate the Securities Act,
      and may issue stop-transfer orders covering such shares. Share certificates
      evidencing Stock issued on exercise of the Option shall bear an appropriate
      legend referring to the provisions of this subsection (c) and the
      agreements herein. The written representation and agreement referred to in
      the
      first sentence of this subsection (c) shall, however, not be required if
      the shares to be issued pursuant to such exercise have been registered under
      the
      Securities Act, and such registration is then effective in respect of such
      shares; and

    
       

      
        
           

        

        
          
            STOCK
              OPTION AGREEMENT PAGE  3

          

          
            

          

        

        
           

        

      

       

    

    (d) Full
      payment to the Company (or other employer corporation) of all amounts which,
      under federal, state, local or foreign tax law, it is required to withhold
      upon
      exercise of the Option. With the consent of the Committee, shares of Stock
      issuable to the Optionee upon exercise of the Option, having a Fair Market
      Value
      at the date of Option exercise equal to the statutory minimum sums required
      to
      be withheld, may be used to make all or part of such payment; and

    

    (e) In
      the
      event the Option or portion thereof shall be exercised pursuant to
      Section 4.1 by any person or persons other than the Optionee, appropriate
      proof of the right of such person or persons to exercise the
      Option.

     

    4.4 Conditions
      to Issuance of Stock Certificates.
      The
      shares of Stock deliverable upon the exercise of the Option, or any portion
      thereof, shall be fully paid and nonassessable. The Company shall not be
      required to issue or deliver any certificate or certificates for shares of
      Stock
      purchased upon the exercise of the Option or portion thereof prior to
      fulfillment of all of the following conditions:

     

    (a) The
      admission of such shares to listing on all stock exchanges on which such Stock
      is then listed; and

     

    (b) The
      completion of any registration or other qualification of such shares under
      any
      state or federal law or under rulings or regulations of the Securities and
      Exchange Commission or of any other governmental regulatory body, which the
      Committee shall, in its absolute discretion, deem necessary or advisable;
      and

     

    (c) The
      obtaining of any approval or other clearance from any state or federal
      governmental agency which the Committee shall, in its absolute discretion,
      determine to be necessary or advisable; and

     

    (d) The
      receipt by the Company of full payment for such shares, including payment of
      all
      amounts which, under federal, state or local tax law, the Company (or other
      employer corporation) is required to withhold upon exercise of the Option;
      and

     

    (e) The
      lapse
      of such reasonable period of time following the exercise of the Option as the
      Committee may from time to time establish for reasons of administrative
      convenience.

     

    4.5 Rights
      as Stockholder.
      The
      holder of the Option shall not be, nor have any of the rights or privileges
      of,
      a stockholder of the Company in respect of any shares purchasable upon the
      exercise of any part of the Option unless and until certificates representing
      such shares shall have been issued by the Company to such holder.

    
       

      
        
           

        

        
          
            STOCK
              OPTION AGREEMENT PAGE  4

          

          
            

          

        

        
           

        

      

       

      ARTICLE
        V

    

    OTHER
      PROVISIONS

     

    5.1 Administration.
      The
      Committee shall have the power to interpret the Plan and this Agreement and
      to
      adopt such rules for the administration, interpretation and application of
      the
      Plan as are consistent therewith and to interpret, amend or revoke any such
      rules. All actions taken and all interpretations and determinations made by
      the
      Committee in good faith shall be final and binding upon the Optionee, the
      Company and all other interested persons. No member of the Committee shall
      be
      personally liable for any action, determination or interpretation made in good
      faith with respect to the Plan, this Agreement or the Option. In its absolute
      discretion, the Board may at any time and from time to time exercise any and
      all
      rights and duties of the Committee under the Plan and this Agreement;
provided,
      however, any
      action taken by the Board in connection with the administration of the Plan
      shall not be deemed approved by the Board unless such actions are approved
      by a
      majority of the Independent Directors.

     

    5.2 Option
      Not Transferable.

     

    (a) Subject
      to Section 5.2(b), the Option may not be sold, pledged, assigned or transferred
      in any manner other than by will or the laws of descent and distribution unless
      and until the Option has been exercised, or the shares underlying such Option
      have been issued, and all restrictions applicable to such shares have lapsed.
      Neither the Option nor any interest or right therein shall be liable for the
      debts, contracts or engagements of the Optionee or his or her successors in
      interest or shall be subject to disposition by transfer, alienation,
      anticipation, pledge, encumbrance, assignment or any other means whether such
      disposition be voluntary or involuntary or by operation of law by judgment,
      levy, attachment, garnishment or any other legal or equitable proceedings
      (including bankruptcy), and any attempted disposition thereof shall be null
      and
      void and of no effect, except to the extent that such disposition is permitted
      by the preceding sentence.

     

    (b) Notwithstanding
      any other provision in this Agreement, with the consent of the Committee, the
      Option may be transferred to, exercised by and paid to certain persons or
      entities related to the Optionee, including but not limited to members of the
      Optionee’s family, charitable institutes or trusts or other entities whose
      beneficiaries or beneficial owners are members of the Optionee’s family or to
      such other persons or entities as may be expressly approved by the Committee
      (each a “Permitted
      Transferee”),
      pursuant to such conditions and procedures as the Committee may
      require.

     

    (c) Unless
      transferred to a Permitted Transferee in accordance with Section 5.2(b), during
      the lifetime of the Optionee, only the Optionee may exercise the Option or
      any
      portion thereof. Subject to such conditions and procedures as the Committee
      may
      require, a Permitted Transferee may exercise the Option or any portion thereof
      during the Optionee’s lifetime. After the death of the Optionee, any exercisable
      portion of the Option may, prior to the time when the Option becomes
      unexercisable under Section 3.3, be exercised by the Optionee’s beneficiary
      designated in accordance with Section 9.4 of the Plan. If no beneficiary has
      been designated or survives the Optionee, the Option may be exercised by the
      person entitled to such exercise pursuant to the Optionee’s will or the laws of
      descent and distribution.

    
       

      
        
           

        

        
          
            STOCK
              OPTION AGREEMENT PAGE  5

          

          
            

          

        

        
           

        

      

       

    

    5.3 Restrictive
      Legends and Stop-Transfer Orders.

     

    (a) The
      share
      certificate or certificates evidencing the shares of Stock purchased hereunder
      shall be endorsed with any legends that may be required by state or federal
      securities laws.

     

    (b) The
      Optionee agrees that, in order to ensure compliance with the restrictions
      referred to herein, the Company may issue appropriate “stop transfer”
instructions to its transfer agent, if any, and that, if the Company transfers
      its own securities, it may make appropriate notations to the same effect in
      its
      own records.

     

    (c) The
      Company shall not be required: (i) to transfer on its books any shares of Stock
      that have been sold or otherwise transferred in violation of any of the
      provisions of this Agreement, or (ii) to treat as owner of such shares of Stock
      or to accord the right to vote or pay dividends to any purchaser or other
      transferee to whom such shares shall have been so transferred.

     

    5.4 Shares
      to Be Reserved.
      The
      Company shall at all times during the term of the Option reserve and keep
      available such number of shares of Stock as will be sufficient to satisfy the
      requirements of this Agreement.

     

    5.5 Notices.
      Any
      notice to be given under the terms of this Agreement to the Company shall be
      addressed to the Company in care of the Secretary, and any notice to be given
      to
      the Optionee shall be addressed to the Optionee at the address given beneath
      the
      Optionee’s signature on the Grant Notice. By a notice given pursuant to this
      Section 5.5, either party may hereafter designate a different address for
      notices to be given to that party. Any notice which is required to be given
      to
      the Optionee shall, if the Optionee is then deceased, be given to the Optionee’s
      designated beneficiary if any, or the person otherwise entitled to exercise
      his
      or her Option pursuant to Section 4.1 by written notice under this
      Section 5.5.  Any notice shall be deemed duly given when sent via
      email or enclosed in a properly sealed envelope or wrapper addressed as
      aforesaid and deposited (with postage prepaid) in a post office or branch post
      office regularly maintained by the United States Postal Service.

     

    5.6 Titles.
      Titles
      are provided herein for convenience only and are not to serve as a basis for
      interpretation or construction of this Agreement.

     

    5.7 Stockholder
      Approval Not Required.
      The
      Plan will not be submitted for approval by the Company’s stockholders. As more
      particularly described in Section 15.1 of the Plan,
      pursuant
      to NASD Rule 4350(i)(1)(A)(iv), the issuance of this Option and the shares
      of
      Common Stock issuable upon exercise or vesting of such Option pursuant to the
      Plan are not subject to the approval of the Company’s stockholders.

     

    5.8 Construction.
      This
      Agreement shall be administered, interpreted and enforced under the laws of
      the
      State of Delaware without regard to conflicts of laws thereof.

     

    5.9 Conformity
      to Applicable Laws.
      The
      Optionee acknowledges that the Plan is intended to conform to the extent
      necessary with all provisions of the Securities Act and the Exchange Act and
      any
      and all regulations and rules promulgated by the Securities and Exchange
      Commission thereunder, and state securities laws and regulations. The Optionee
      also acknowledges that the Plan is intended to conform with the requirements
      of
      rules promulgated by the NASD and, without limiting the foregoing, in particular
      NASD
      Rule
      4350(i)(1)(A)(iv). Notwithstanding
      anything herein to the contrary, the Plan shall be administered, and the Option
      is granted and may be exercised, only in such a manner as to conform to such
      laws, rules and regulations. To the extent permitted by applicable law, the
      Plan
      and this Agreement shall be deemed amended to the extent necessary to conform
      to
      such laws, rules and regulations.

    
       

      5.10 Amendments.
        This Agreement may not be modified, amended or terminated except by an
        instrument in writing, signed by the Optionee or such other person as may
        be
        permitted to exercise the Option pursuant to Section 4.1 and by a duly
        authorized representative of the Company.

    

     

    
      
        
           

        

        
          
            STOCK
              OPTION AGREEMENT PAGE  6

          

          
            

          

        

        
           

        

      

       

    

    EXHIBIT
      A 

     

    TO
      GRANT NOTICE AND STOCK OPTION AGREEMENT

     

    FORM
      OF EXERCISE NOTICE

     

    

    Effective
      as of today, ___________, _____, the undersigned (“Optionee”)
      of
      this Exercise Notice (the “Agreement”)
      hereby
      elects to exercise Optionee’s option to purchase _________ shares of common
      stock (the “Shares”)
      of
      Sunesis Pharmaceuticals, Inc. (the “Company”)
      under
      and pursuant to the Sunesis Pharmaceuticals, Inc. 2006
      Employment Commencement Incentive Plan
      (the
“Plan”)
      and
      the Grant Notice and Stock Option Agreement dated _____________, _____, (the
      “Option
      Agreement”).
      Capitalized terms used herein without definition shall have the meanings given
      in the Option Agreement.

     

    
      	
              Grant
                Date:

            	 	 
	 	 	 
	
              Number
                of Shares as to which Option is Exercised:

            	 	 
	 	 	 
	
              Exercise
                Price per Share:

            	 	
              $____________

            
	 	 	 
	
              Total
                Exercise Price:

            	 	
              $____________

            
	 	 	 
	
              Certificate
                to be issued in name of:

            	 	 
	 	 	 
	
              Cash
                Payment delivered herewith: 

            	 	
              $____________
                (Representing the full Exercise Price for the Shares, as well as
                any
                applicable withholding tax)

            

    

    

    Type
      of Option:   This
      Option is a Non-Qualified Stock Option.

    

    1. Representations
      of Optionee.
      Optionee acknowledges that Optionee has received, read and understood the Plan
      and the Option Agreement. Optionee agrees to abide by and be bound by their
      terms and conditions. 

     

    2. Rights
      as Stockholder.
      Until
      the stock certificate evidencing such Shares is issued (as evidenced by the
      appropriate entry on the books of the Company or of a duly authorized transfer
      agent of the Company), no right to vote or receive dividends or any other rights
      as a stockholder shall exist with respect to Shares subject to the Option,
      notwithstanding the exercise of the Option. The Company shall issue (or cause
      to
      be issued) such stock certificate promptly after the Option is exercised. No
      adjustment will be made for a dividend or other right for which the record
      date
      is prior to the date the stock certificate is issued, except as provided in
      Article 10 of the Plan. 

     

    3. Tax
      Consultation.
      Optionee understands that Optionee may suffer adverse tax consequences as a
      result of Optionee’s purchase or disposition of the Shares. Optionee represents
      that Optionee has consulted with any tax consultants Optionee deems advisable
      in
      connection with the purchase or disposition of the Shares and that Optionee
      is
      not relying on the Company for any tax advice.

     

    4. Successors
      and Assigns.
      The
      Company may assign any of its rights under this Agreement to single or multiple
      assignees, and this Agreement shall inure to the benefit of the successors
      and
      assigns of the Company. Subject to the restrictions on transfer herein set
      forth, this Agreement shall be binding upon Optionee and his or her heirs,
      executors, administrators, successors and assigns.

     

    
      
         

      

      
        
          EXERCISE
            NOTICE PAGE 1

        

        
          

        

      

      
         

      

    

     

    5. Interpretation.
      Any
      dispute regarding the interpretation of this Agreement shall be submitted by
      Optionee or by the Company forthwith to the Committee, which shall review such
      dispute at its next regular meeting. The resolution of such a dispute by the
      Committee shall be final and binding on the Company and on
      Optionee.

     

    6. Governing
      Law; Severability.
      This
      Agreement shall be governed by and construed in accordance with the laws of
      the
      State of Delaware excluding that body of law pertaining to conflicts of law.
      Should any provision of this Agreement be determined by a court of law to be
      illegal or unenforceable, the other provisions shall nevertheless remain
      effective and shall remain enforceable.

     

    7. Notices.
      Any
      notice required or permitted hereunder shall be given in accordance with the
      provisions set forth in Section 5.5 of the Option Agreement.

     

    8. Further
      Instruments.
      The
      parties agree to execute such further instruments and to take such further
      action as may be reasonably necessary to carry out the purposes and intent
      of
      this Agreement.

     

    9. Entire
      Agreement.
      The
      Plan and Option Agreement are incorporated herein by reference. This Agreement,
      the Plan and the Option Agreement constitute the entire agreement of the parties
      and supersede in their entirety all prior undertakings and agreements of the
      Company and Optionee with respect to the subject matter hereof.

     

    

    
      	
              ACCEPTED
                BY:

            	
              SUBMITTED
                BY:

            
	 	 
	
              SUNESIS
                PHARMACEUTICALS, INC.

            	
              OPTIONEE

            
	 	 
	
              By:______________________________

            	_____________________________
	
              Name:____________________________

            	
              Optionee

            
	
              Its:______________________________

            	 
	 	 
	 	
              Address:

              _________________________________

              _________________________________

              _________________________________

            

    

     

    
       

      
        
           

        

        
          
            EXERCISE
              NOTICE PAGE 2

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00145-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00145-of-00352.parquet"}]]