Document:

EX-10.7

 

EXHIBIT 10.7

AMENDMENT NO. 1 TO

ATHERSYS, INC. AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT

     This Amendment No. 1, dated as of January 29, 2002 (this “Amendment”) to the Amended and
Restated Registration Rights Agreement (the “Agreement”) dated as of April 28, 2000, is by and
among Athersys, Inc., a Delaware corporation (the “Company”), the New Stockholders (as defined
below) (the “New Stockholders”), the Investors, Biotech and the Stockholders (each as defined in
the Agreement).

RECITALS:

     WHEREAS, the Company and certain investors (the “New Stockholders”) have entered into
Securities Purchase Agreements, dated as of the date hereof (collectively, the “Securities Purchase
Agreements"), pursuant to which the New Stockholders agreed to purchase from the Company shares of
the Company’s Common Stock, par value $.01 per share, on certain terms and conditions contained in
the Securities Purchase Agreements; and

     WHEREAS, it is a condition precedent to the closing of the transactions contemplated by each
Securities Purchase Agreement, that the Company, the Investors, Biotech and the Stockholders enter
into this Amendment and that the New Stockholders become party to the Agreement and this Amendment.

AGREEMENTS:

     NOW, THEREFORE, the parties hereto, intending to be legally bound, agree as follows:

     1. Effective as of the date of this Amendment, the New Stockholders will be included on
Schedule B to the Agreement and such New Investors shall for all purposes under the
Agreement be Stockholders (as defined in the Agreement).

     2. All covenants and agreements in this Amendment by or on behalf of any of the parties hereto
will bind and inure to the benefit of the respective successors and assigns of the parties hereto
whether so expressed or not.

     3. This Amendment may be executed in two or more counterparts, each of which constitutes an
original, and all of which taken together shall constitute one and the same Amendment.

     4. This Amendment shall be governed by the laws of the State of Delaware, without reference to
its conflict of law principles.

     5. Where necessary or appropriate to the meaning hereof, the singular, plural, masculine,
feminine and neuter shall be deemed to include each other.

 

 

     6. Whenever possible, each provision of this Amendment shall be interpreted in such manner as
to be effective and valid under applicable law, but if any provision of this Amendment is held to
be prohibited by or invalid under applicable law, such provision shall be ineffective only to the
extent of such prohibition or invalidity, without invalidating the remainder of this Amendment.

     7. This Amendment and the Agreement constitute the entire agreement of the parties and there
are no other agreements, written or oral, between the parties related to the subject matter of this
Amendment and the Agreement.

     8. Capitalized terms used but not otherwise defined herein have the meanings set forth in the
Agreement.

[SIGNATURES BEGIN ON FOLLOWING PAGE]

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     IN WITNESS WHEREOF, the parties have executed this Amendment No. 1 to Amended and Restated
Registration Rights Agreement as of the day and year first above written.

	 	 	 	 	 
	 	ATHERSYS, INC.

 	 
	 	By:  	/s/
Gil Van Bokkelen	 
	 	 	Gil Van Bokkelen 	 
	 	 	President and Chief Executive Officer 	 
	 

[SIGNATURES CONTINUE ON FOLLOWING PAGE]

 

	 	* Note:	 	conformed signatures of New Stockholders,
Investors, Biotech and the Stockholders intentionally omitted from
this filing.

-3-EX-10.8

 

EXHIBIT
10.8

AMENDMENT NO. 2 TO

ATHERSYS, INC. AMENDED AND RESTATED REGISTRATION RIGHTS

AGREEMENT

     This Amendment No. 2, dated as of November 19, 2002 (this “Amendment”) to the Amended and
Restated Registration Rights Agreement dated as of April 28, 2000, and as amended by Amendment No.
1 to Athersys, Inc. Amended and Restated Registration Rights Agreement dated as of January 29, 2002
(as so amended, the “Agreement”), is by and among Athersys, Inc., a Delaware corporation (the
“Company”), the New Stockholders (as defined below), the Investors, Biotech and the Stockholders
(each as defined in the Agreement).

RECITALS:

     WHEREAS, the Company, MCL LLC (“MCL”) and Leo T. Furcht, M.D. (“Furcht”) have entered into an
Option Agreement (the “Option Agreement”), pursuant to which the Company has granted MCL an
irrevocable option, exercisable at certain times and under certain conditions as set forth in the
Option Agreement, to cause MCL to merge with and into a wholly owned subsidiary of the Company on
the terms and conditions set forth in an agreement and plan of merger to be entered into by and
among the Company, Merger Sub, MCL and Furcht (the “Merger Agreement”), and (ii) MCL has granted
to the Company an irrevocable option, exercisable at certain times and under certain conditions as
set forth in the Option Agreement, to cause MCL to merge with and into Merger Sub on the terms and
conditions set forth in the Merger Agreement; and

     WHEREAS, pursuant to the terms of the Merger Agreement, shares of the Company’s Common Stock,
par value $.01 per share, are to be issued on the terms and conditions contained in the Merger
Agreement to the Holders, as defined in the Merger Agreement (the “New Stockholders”); and

     WHEREAS, it is a condition precedent to the closing of the transactions contemplated by the
Merger Agreement, that the Company, the Investors, Biotech and the Stockholders enter into this
Amendment and that the New Stockholders become party to the Agreement and this Amendment.

AGREEMENTS:

     NOW, THEREFORE, the parties hereto, intending to be legally bound, agree as follows:

     1. Effective as of the Effective Time, as defined in the Merger Agreement, the New
Stockholders will be included on Schedule B to the Agreement and thereafter deemed to be
parties to such Agreement and such New Stockholders thereafter shall for all purposes under the
Agreement be deemed to be Stockholders (as defined in the Agreement).

 

 

     2. Schedule B to the Agreement shall be deemed amended in a manner consistent with
this Agreement.

     3. All covenants and agreements in this Amendment by or on behalf of any of the parties hereto
will bind and inure to the benefit of the respective successors and assigns of the parties hereto
whether so expressed or not.

     4. This Amendment may be executed in multiple counterparts, each of which constitutes an
original, and all of which taken together shall constitute one and the same Amendment.

     5. This Amendment shall be governed by the laws of the State of Delaware, without reference to
its conflict of law principles.

     6. Where necessary or appropriate to the meaning hereof, the singular, plural, masculine,
feminine and neuter shall be deemed to include each other.

     7. Whenever possible, each provision of this Amendment shall be interpreted in such manner as
to be effective and valid under applicable law, but if any provision of this Amendment is held to
be prohibited by or invalid under applicable law, such provision shall be ineffective only to the
extent of such prohibition or invalidity, without invalidating the remainder of this Amendment.

     8. This Amendment and the Agreement constitute the entire agreement of the parties and there
are no other agreements, written or oral, between the parties related to the subject matter of this
Amendment and the Agreement.

     9. Capitalized terms used but not otherwise defined herein have the meanings set forth in the
Agreement.

[SIGNATURES BEGIN ON FOLLOWING PAGE]

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     IN WITNESS WHEREOF, the parties have executed this Amendment No. 2 to Amended and Restated
Registration Rights Agreement as of the day and year first above written.

	 	 	 	 	 
	 	ATHERSYS, INC.

 	 
	 	By:  	/s/ Gil Van Bokkelen	 
	 	 	Gil Van Bokkelen 	 
	 	 	President and Chief Executive Officer 	 

[SIGNATURES CONTINUE ON FOLLOWING PAGE]

 

	 	* Note:	 	conformed signatures of New Stockholders,
Investors, Biotech and the Stockholders intentionally omitted from
this filing.

-3-EX-10.9

 

EXHIBIT
10.9

ATHERSYS, INC.

AMENDMENT NO. 3

TO

AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT

     This Amendment No. 3, dated as of May 15, 2007 (this “Amendment”) to the Amended and Restated
Registration Rights Agreement (the “Agreement”) dated as of April 28, 2000, as amended, is by and
among Athersys, Inc., a Delaware corporation (the “Company”), and the holders of shares of capital
stock of the Company who from time to time have executed counterparts to the Agreement
(collectively, the “Existing Stockholders”).

RECITALS:

     WHEREAS, the Company plans to effect a transaction by which a wholly owned subsidiary of a
publicly traded company (“PubCo”) will merge with and into the Company, the Company will become a
wholly owned subsidiary of PubCo, and the existing stockholders of the Company will obtain majority
ownership and control of PubCo immediately after such transaction (the “Merger”);

     WHEREAS, concurrent with and as a condition to the closing of the Merger, PubCo intends to
conduct a private placement transaction (the “Offering”) pursuant to Regulation D promulgated under
the Securities Act of 1933, as amended;

     WHEREAS, in connection with the Offering, PubCo, the Company and certain investors (the “New
Stockholders”) will enter into a Securities Purchase Agreement (the “Securities Purchase
Agreement”), the form of which is attached hereto as Exhibit A, pursuant to which the New
Stockholders agree to purchase from PubCo Units consisting of one share of Pubco’s common stock
(“Common Stock”) and a warrant (a “Warrant”) to purchase 0.25 shares of Common Stock on certain
terms and conditions contained in the Securities Purchase Agreement;

     WHEREAS, the New Stockholders and certain other holders of securities of PubCo (collectively,
the “Holders”) will be granted registration rights relating to Common Stock pursuant to the terms
of the Securities Purchase Agreement;

     WHEREAS, pursuant to Section 10 of the Agreement, the Existing Stockholders must approve any
future agreement granting registration rights to any holders of the Company’s securities;

     WHEREAS, it is a condition precedent to the closing of the Offering and the Merger that the
Existing Stockholders waive certain rights existing under this Agreement; and

     WHEREAS, under Section 13(d) of the Agreement, the Existing Stockholders may waive any rights
granted to them under the Agreement.

 

 

AGREEMENTS:

     NOW, THEREFORE, the parties hereto, intending to be legally bound, agree as follows:

     1. Effective as of the date of this Amendment, the Existing Stockholders hereby approve the
Securities Purchase Agreement and the registration rights granted therein.

     2. Effective as of the date of this Amendment, the Existing Stockholders hereby waive any
rights to Piggyback Registration granted under Section 2 of the Agreement in connection with any
registration rights granted to or exercised by the Holders under the Securities Purchase Agreement,
except and only to the extent permitted by Section 6.7 of the Securities Purchase Agreement.

     3. Effective as of the date of this Amendment, the Existing Stockholders hereby agree that, in
connection with an underwritten public offering as described in Section 6.7 of the Securities
Purchase Agreement, the Holders and the Existing Stockholders shall have the priorities with
respect to inclusion in such offering provided for in the Securities Purchase Agreement, and that,
where inconsistent, the terms of the Securities Purchase Agreement shall supersede the terms of the
Agreement for any such offering.

     4. Effective as of the date of this Amendment, the Existing Stockholders hereby agree that
they will not exercise any rights to Demand Registration granted under Section 3 of the Agreement
from and after the date of this Amendment until the date six months following (i) the effective
date of the registration statement filed pursuant to Section 6.1 of the Securities Purchase
Agreement or (ii) in the event that the Company is required to file any additional registration
statements pursuant to Section 6.8 of the Securities Purchase Agreement, until the later of (a) the
one-year anniversary of the First Closing under the Securities Purchase Agreement and (b) the
six-month anniversary of the effective date of the first registration statement filed pursuant to
Section 6.1 of Securities Purchase Agreement that is declared effective by the SEC.

     5. All covenants and agreements in this Amendment by or on behalf of any of the parties hereto
will bind and inure to the benefit of the respective successors and assigns of the parties hereto
whether so expressed or not.

     6. This Amendment may be executed in two or more counterparts, each of which constitutes an
original, and all of which taken together shall constitute one and the same Amendment. It is
understood that all parties need not sign the same counterpart. In the event that any signature is
delivered by facsimile transmission or by email delivery of a “.pdf” format data file, such
signature shall create a valid and binding obligation of the party executing (or on whose behalf
such signature is executed) with the same force and effect as if such facsimile or “.pdf” signature
page were an original thereof.

     7. This Amendment shall be governed by the laws of the State of Delaware, without reference to
its conflict of law principles.

     8. Where necessary or appropriate to the meaning hereof, the singular, plural,

-2-

 

masculine, feminine and neuter shall be deemed to include each other.

     9. Whenever possible, each provision of this Amendment shall be interpreted in such manner as
to be effective and valid under applicable law, but if any provision of this Amendment is held to
be prohibited by or invalid under applicable law, such provision shall be ineffective only to the
extent of such prohibition or invalidity, without invalidating the remainder of this Amendment.

     10. This Amendment and the Agreement constitute the entire agreement of the parties and there
are no other agreements, written or oral, between the parties related to the subject matter of this
Amendment and the Agreement.

     11. Capitalized terms used but not otherwise defined herein have the meanings set forth in the
Agreement.

[SIGNATURES BEGIN ON FOLLOWING PAGE]

-3-

 

     IN WITNESS WHEREOF, the parties have executed this Amendment No. 3 to the Amended and Restated
Registration Rights Agreement of Athersys, Inc. as of the day and year first above written.

	 	 	 	 	 
	 	ATHERSYS, INC.

 	 
	 	By:  	/s/  William Lehmann	 
	 	 	William Lehmann 	 
	 	 	President 	 
	 

[SIGNATURES CONTINUE ON FOLLOWING PAGE]

*Note:
conformed signatures of Existing Stockholders intentionally omitted from
this filing.

-4-

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