Document:

Nonstatutory Stock Option Agreement (for Director Options)

 Exhibit 10.4.1 
 ICAGEN, INC. 
 Nonstatutory Stock Option Agreement

 Granted Under 2004 Stock Incentive Plan 
 [FOR DIRECTOR OPTIONS] 
 [NOTE: Such director options
may only be granted to the individual who is director] 
  

	1.	Grant of Option. 

 This
agreement evidences the grant by Icagen, Inc., a Delaware corporation (the “Company”), on                     ,
200   (the “Grant Date”) to                     , a director of the Company (the “Participant”),
of an option to purchase, in whole or in part, on the terms provided herein and in the Company’s 2004 Stock Incentive Plan (the “Plan”), a total of
                     shares (the “Shares”) of common stock, $0.001 par value per share, of the Company (“Common
Stock”) at $             per Share. Unless earlier terminated, this option shall expire at 5:00 p.m., Eastern time, on
                     (the “Final Exercise Date”). 
 It is intended that the option evidenced by this agreement shall not be an incentive stock option as defined in Section 422 of the Internal
Revenue Code of 1986, as amended, and any regulations promulgated thereunder (the “Code”). Except as otherwise indicated by the context, the term “Participant”, as used in this option, shall be deemed to include any person who
acquires the right to exercise this option validly under its terms. 
  

	2.	Vesting Schedule. 

 This
option will become exercisable (“vest”) as to
                                         
                                        .

  

	3.	Exercise of Option. 

 (a)
Form of Exercise. Each election to exercise this option shall be in writing, signed by the Participant, and received by the Company at its principal office, accompanied by this agreement, and payment in full as follows: 
 (1) in cash or by check, payable to the order of the Company; 
 (2) by (i) delivery of an irrevocable and unconditional undertaking by a creditworthy broker to deliver promptly to the
Company sufficient funds to pay the exercise price and any required tax withholding or (ii) delivery by the Participant to the Company of a copy of irrevocable and unconditional instructions to a creditworthy broker to deliver promptly to the
Company cash or a check sufficient to pay the exercise price and any required tax withholding; 

 (3) with the approval of the Board, when the Common Stock is registered
under the Exchange Act, by delivery of shares of Common Stock owned by the Participant valued at their fair market value as determined by (or in a manner approved by) the Board in good faith (“Fair Market Value”), provided (i) such method
of payment is then permitted under applicable law and (ii) such Common Stock, if acquired directly from the Company, was owned by the Participant at least six months prior to such delivery; 
 (4) to the extent permitted by applicable law and by the Board, in its sole discretion by (i) delivery of a promissory note
of the Participant to the Company on terms determined by the Board, or (ii) payment of such other lawful consideration as the Board may determine; or 
 (5) by any combination of the above permitted forms of payment. 
 The Participant may purchase
less than the number of shares covered hereby, provided that no partial exercise of this option may be for any fractional share. 
 (b) Exercise Period. The right to exercise this option shall terminate on the Final Exercise Date. Notwithstanding the foregoing, if the Participant, prior to the Final Exercise Date, violates the non-competition or
confidentiality provisions of any employment contract, confidentiality and nondisclosure agreement or other agreement between the Participant and the Company, the right to exercise this option shall terminate immediately upon such violation.

  

	4.	Agreement in Connection with Public Offering. 

 The Participant agrees, in connection with an underwritten public offering of the Company’s securities pursuant to a registration statement under the Securities Act, (i) not to sell, make short sale
of, loan, grant any options for the purchase of, or otherwise dispose of any shares of Common Stock held by the Participant (other than those shares included in the offering) without the prior written consent of the Company or the underwriters
managing such initial underwritten public offering of the Company’s securities for such number of days (not to exceed 180 days) from the effective date of such registration statement as the Company or the managing underwriters may require, and
(ii) to execute any agreement reflecting clause (i) above as may be requested by the Company or the managing underwriters at the time of such offering. 
  

	5.	Withholding. 

 No Shares
will be issued pursuant to the exercise of this option unless and until the Participant pays to the Company, or makes provision satisfactory to the Company for payment of, any federal, state or local withholding taxes required by law to be withheld
in respect of this option. When the Common Stock is registered under the Exchange Act, Participant may satisfy such tax obligations in whole or in part by delivery of shares of Common Stock owned by Participant valued at their Fair Market Value;
provided, however, that the total tax withholding where stock is being used to satisfy such tax obligations cannot exceed the Company’s minimum statutory withholding obligations (based on minimum statutory withholding rates for federal and
state tax purposes, including payroll taxes, that are applicable to such supplemental taxable

  

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income). The Company may, to the extent permitted by law, deduct any such tax obligations from any payment of any kind otherwise due to Participant. 
  

	6.	Nontransferability of Option. 

 This option may not be sold, assigned, transferred, pledged or otherwise encumbered by the Participant, either voluntarily or by operation of law, except by will or the laws of descent and distribution, and, during the lifetime of the
Participant, this option shall be exercisable only by the Participant. 
  

	7.	Provisions of the Plan. 

 This option is subject to the provisions of the Plan, a copy of which is furnished to the Participant with this option. 
 IN WITNESS WHEREOF, the Company has caused this option to be executed under its corporate seal by its duly authorized officer. This option shall take effect as a sealed instrument. 

											
		 		 		 		 	Icagen, Inc.
						
	Dated:	 	 	 		 		 	By:	 	 
		 		 		 		 		 	Name:
		 		 		 		 		 	Title:

  

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 PARTICIPANT’S ACCEPTANCE 
 The undersigned hereby accepts the foregoing option and agrees to the terms and conditions thereof. The undersigned hereby acknowledges
receipt of a copy of the Company’s 2004 Stock Incentive Plan. 
  

			
	PARTICIPANT:
	
	 
		
	 Address: 
	 	 
		
		 	 

  

 42004 Stock Incentive Plan

 Exhibit 10.5 
 ICAGEN, INC. 
 2004 STOCK INCENTIVE PLAN 
 RESTRICTED STOCK UNIT AGREEMENT 
 This RESTRICTED STOCK UNIT AGREEMENT (the “Agreement”), dated as of
                         (the “Date of Grant”), is delivered by Icagen, Inc., a Delaware corporation
(“Icagen”), to                         (the “Grantee”). 
 RECITALS 
 The Icagen, Inc. 2004 Stock Incentive Plan (the “Plan”) provides for the grant of stock-based awards with respect to shares of common stock, par value $0.001 per share, of Icagen (the “Common Stock”), in accordance with
the terms and conditions of the Plan. The Compensation Committee of the Board of Directors of Icagen (the “Committee”) has determined to make a stock-based award in the form of a grant of stock units, subject to the terms and conditions
set forth in this Agreement and the Plan. The Grantee may obtain a copy of the Plan by contacting the Human Resources Manager at Icagen. 
 NOW, THEREFORE, the parties to this Agreement, intending to be legally bound hereby, agree as follows: 
 1. Grant of Restricted Stock Units. Subject to the terms and conditions set forth in this Agreement and the Plan and as of the Date of Grant, Icagen hereby grants to the
Grantee                         stock units (the “Restricted Stock Units”) under the Plan. The Grantee accepts
the Restricted Stock Units and agrees to be bound by the terms and conditions of this Agreement and the Plan with respect to the Restricted Stock Units. 
 2. Restricted Unit Account. The Restricted Stock Units represent the right to receive shares of Common Stock, subject to the vesting and other terms and conditions of this Agreement, and are not
actual shares of stock. Icagen shall establish and maintain a Restricted Stock Unit account, as a bookkeeping account on its records, for the Grantee and shall record in such account the number of Restricted Stock Units granted to the Grantee. No
shares of stock shall be issued to the Grantee at the time the grant is made, and the Grantee shall not be, nor have any of the rights or privileges of, a stockholder of Icagen with respect to any Restricted Stock Units recorded in the account. The
Grantee shall not have the right to receive any dividends or other distributions with respect to Restricted Stock Units recorded in the Grantee’s account; provided, however, that the Committee may appropriately adjust the number and kind of
Restricted Stock Units in the event of a stock split, stock dividend or other change in capitalization of Icagen, as provided in the Plan. The Grantee shall not have any interest in any fund or specific assets of Icagen by reason of this award or
the Restricted Unit account established for the Grantee. 

	3.	Vesting of Restricted Stock Units. 

 The Restricted Stock Units shall vest, and shall be subject to forfeiture according to the following schedule, subject to the Grantee’s continuous employment by, or engagement to provide service to,
Icagen from the Date of Grant until the applicable vesting date: 
  

			
	 Vesting Date
	  	 Restricted Stock Units

		
	 (the “Final Vesting Date”)
	  	

 The vesting of the Restricted Stock Units shall be cumulative, but shall not exceed 100% of the Restricted Stock
Units. If the foregoing schedule would produce fractional Units, the number of vested Restricted Stock Units shall be rounded down to the nearest whole Unit, with all Restricted Stock Units vesting as of the Final Vesting Date if the Grantee is then
employed by, or providing service to, Icagen. 
  

	4.	Issuance of Common Stock. 

 (a) When the Restricted Stock Units vest as described above, such Restricted Stock Units shall no longer be subject to forfeiture. Subject to the terms of this Agreement, Icagen shall issue or cause to be
issued to the Grantee one share of Common Stock for each whole vested Restricted Unit on, or as soon as practicable after, each vesting date set forth above (but in any event by the thirtieth (30th) day following each such vesting date), subject to the satisfaction of the Grantee’s tax
withholding obligations as described below. No fractional shares shall be issued under this Agreement and any fractional Units shall be handled as provided in Paragraph 3 hereof. 
 (b) All obligations of Icagen and rights of Grantee under this Agreement shall be subject to the rights of Icagen as set forth in the Plan
to withhold amounts required to be withheld for applicable taxes. The Grantee may elect with a five business day advance notice to Icagen to satisfy any tax withholding obligation of Icagen with respect to the Restricted Stock Units by either a cash
payment to Icagen or having shares of Common Stock withheld by Icagen up to an amount that does not exceed the minimum applicable withholding tax rate for federal (including FICA), state, and local tax liabilities (“Applicable Withholding
Taxes”), subject to the terms of Section 9(e) of the Plan. If no election has been made, Icagen will withhold shares to satisfy withholding obligations, and Grantee hereby authorizes Icagen to distribute the shares of Common Stock with
respect to the Restricted Stock Units net of the number of whole shares of Common Stock the aggregate market value of which is equal to the minimum Applicable Withholding Taxes. The Grantee further agrees that any additional amounts required for
payment of the Applicable Withholding Taxes may be withheld by Icagen from any other payments due to Grantee, including through the Grantee’s paycheck. 
  

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 (c) The obligation of Icagen to deliver shares hereunder shall also be subject to the
condition that if at any time the Committee shall determine in its discretion that the listing, registration or qualification of the shares of Common Stock upon any securities exchange or under any state or federal law, or the consent or approval of
any governmental regulatory body, is necessary or desirable as a condition of, or in connection with, the issue of shares, the shares may not be issued in whole or in part unless such listing, registration, qualification, consent or approval shall
have been effected or obtained free of any conditions not acceptable to the Committee. The issuance of shares of Common Stock to the Grantee pursuant to this Agreement is subject to any applicable taxes and other laws or regulations of the United
States or of any state having jurisdiction thereof. 
 (d) The Grantee agrees to be bound by Icagen’s policies regarding
transfer of shares of Common Stock and understands that there may be certain times during the year in which the Grantee will be prohibited from selling, transferring, pledging, donating, assigning, mortgaging, hypothocating or encumbering shares.

 5. Termination of Restricted Stock Units. If the Grantee ceases to be employed by, or provide service to, Icagen for any reason before
the vesting of any of the Restricted Stock Units, any Restricted Stock Units for which vesting has not occurred according to the vesting schedule above shall automatically terminate and shall be forfeited as of the date of the Grantee’s
termination of employment or service. No payment or issuance of Common Stock shall be made with respect to any Restricted Stock Units that terminate as described in this Paragraph 5. 
 6. Change of Control. The provisions of the Plan applicable to a Change of Control Event (as defined in the Plan) as set forth in Section 8(c)(4)(b) of the Plan shall apply to the Restricted
Stock Units, and, in the event of a Change of Control Event, the Committee may take such actions as it deems appropriate pursuant to the Plan. In the event of a Reorganization Event (as defined in the Plan) that is not a Change of Control Event, the
provisions set forth in Section 8(c)(3)(a) of the Plan shall apply to the Restricted Stock Units and this grant. 
 7. Grant Subject to
Plan Provisions. This grant is made pursuant to the Plan, the terms of which are incorporated herein by reference, and in all respects shall be interpreted in accordance with the Plan. The grant and payment of the Restricted Stock Units are
subject to interpretations, regulations and determinations concerning the Plan established from time to time by the Committee in accordance with the provisions of the Plan, including, but not limited to, provisions pertaining to (i) rights and
obligations with respect to withholding taxes, (ii) the registration, qualification or listing of the shares issued under the Plan, (iii) changes in capitalization of Icagen, and (iv) other requirements of applicable law. The
Committee shall have the authority to interpret and construe the Restricted Stock Units pursuant to the terms of the Plan, and its decisions shall be conclusive as to any questions arising hereunder. 
 8. No Employment or Other Rights. The grant of the Restricted Stock Units shall not confer upon the Grantee any right to be retained by or in the
employ or service of Icagen and shall not interfere in any way with the right of Icagen to terminate the Grantee’s employment or service at any time. The right of Icagen to terminate at will the Grantee’s employment or service at any time
for any reason is specifically reserved. 
  

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 9. No Stockholder Rights. Neither the Grantee, nor any person entitled to receive payment in the
event of the Grantee’s death, shall have any of the rights and privileges of a stockholder with respect to shares of Common Stock, until certificates for shares have been issued upon payment of Restricted Stock Units. 
 10. Assignment and Transfers. Except as the Committee may otherwise permit pursuant to the Plan, the rights and interests of the Grantee under this
Agreement may not be sold, assigned, encumbered or otherwise transferred except, in the event of the death of the Grantee, by will or by the laws of descent and distribution. In the event of any attempt by the Grantee to alienate, assign, pledge,
hypothecate, or otherwise dispose of the Restricted Stock Units or any right hereunder, except as provided for in this Agreement, or in the event of the levy or any attachment, execution or similar process upon the rights or interests hereby
conferred, Icagen, may terminate the Restricted Stock Units by notice to the Grantee, and the Restricted Stock Units and all rights hereunder shall thereupon become null and void. The rights and protections of Icagen hereunder shall extend to any
successors or assigns of Icagen, and to Icagen’s parents, subsidiaries, and affiliates, as applicable. This Agreement may be assigned by Icagen without the Grantee’s consent. 
 11. Agreement in Connection with Public Offering. The Grantee agrees, in connection with an underwritten public offering of Icagen’s securities pursuant to a registration statement under the
Securities Act of 1933, as amended, (i) not to sell, make short sale of, loan, grant any options for the purchase of, or otherwise dispose of any shares of Common Stock held by the Grantee (other than those shares included in the offering)
without the prior written consent of Icagen or the underwriters managing such underwritten public offering of Icagen’s securities for such number of days (not to exceed 180 days) from the effective date of such registration statement as the
managing underwriters or Icagen may require, and (ii) to execute any agreement reflecting clause (i) above as may be requested by Icagen or the managing underwriters at the time of such offering. 
 12. Unfunded Arrangement. The Grantee’s rights to receive payments under this Agreement shall be no greater than the right of an unsecured
general creditor of Icagen. All payments shall be made from the general assets of Icagen, and no special or separate fund shall be established and no segregation of assets shall be made to assure payment. 
 13. Tax Consequences. The Grantee acknowledges that the Grantee may be subject to adverse tax consequences as a result of the issuance, vesting
and/or distribution of the Restricted Stock Units and/or the Common Stock and understands that the Grantee should consult a tax advisor as to the tax consequences of the Restricted Stock Units and subsequent distribution of Common Stock. To the
extent that this Agreement, the issuance and vesting of the Restricted Stock Units and/or distribution of Common Stock as set forth in this Agreement is subject to Section 409A of the Internal Revenue Code of 1986, as amended, and any
regulations promulgated thereunder (the “Code”), the Grantee agrees to cooperate and work together with Icagen to timely amend this Grant to comply with Section 409A of the Code as necessary. 
  

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 14. Applicable Law. The validity, construction, interpretation and effect of this Agreement shall be
governed by and construed in accordance with the laws of the State of Delaware, without giving effect to the conflicts of laws provisions thereof. 
 15. Notice. Any notice to Icagen provided for in this Agreement shall be addressed to Icagen, Inc. in care of the Human Resources Manager, at the corporate headquarters of Icagen, and any notice to the Grantee shall be addressed to
such Grantee at the current address shown on the payroll of Icagen, or to such other address as the Grantee may designate to Icagen, in writing. Any notice shall be delivered by hand, sent by telecopy or enclosed in a properly sealed envelope
addressed as stated above, registered and deposited, postage prepaid, in a post office regularly maintained by the United States Postal Service. 
 IN WITNESS WHEREOF, Icagen has caused its duly authorized officer to execute this Restricted Stock Unit Agreement, and the Grantee has placed his signature hereon, effective as of the Date of Grant.

  

			
	ICAGEN, INC.
		
	By:	 	 
	Name:	 	P. Kay Wagoner
	Title:	 	CEO

 ACCEPTANCE: 
 I hereby accept the award of Restricted Stock Units described in this Agreement, and I agree to be bound by the terms of the Plan and this Agreement. I
hereby agree that all of the decisions and determinations of the Committee with respect to the Restricted Stock Units shall be final and binding. 
  

	
	  
	Grantee
	 
	Date

  

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