Document:

Exhibit 10.40

                          PLEDGE AND SECURITY AGREEMENT

      PLEDGE AND SECURITY AGREEMENT, dated as of December 31, 2001 (this
"Agreement"), between (1) ELX LIMITED PARTNERSHIP, a Delaware limited
partnership (the "Pledgor"), and (2) ELXSI CORPORATION, a Delaware corporation
("Parent"), as collateral agent (the "Pledgee"), for the benefit of (i) on a
first priority basis, Parent as the holder of the Parent Notes (as defined
below), and (ii) on a second priority basis, ELXSI, a California corporation
("Subsidiary") and wholly owned subsidiary of Parent, as the holder of the
Subsidiary Notes (as defined below).

                                   Background

      The Pledgor is the "Payor" under that certain: (i) Amended and Restated
Promissory Note, dated as of December 31, 2001 and due April 1, 2005, payable to
Parent and having an original principal amount of $1,606,278 (the "First Parent
Note"), and (ii) Amended and Restated Promissory Note, dated as of December 31,
2001 and due April 1, 2005, payable to Parent and having an original principal
amount of $1,362,489 (the "Second Parent Note"; and collectively with the First
Parent Note, the "Parent Notes").

      Cadmus Corporation, a Massachusetts corporation ("Cadmus"), is the "Payor"
under that certain: (i) Amended and Restated $2,000,000 Secured Promissory Note,
dated as of December 31, 2001 and due April 1, 2005, payable to Subsidiary (the
"First Subsidiary Note"), and (ii) Amended and Restated $7,003,364 Promissory
Note, dated as of December 31, 2001 and due April 1, 2005, payable to Subsidiary
(the "Second Subsidiary Note"; and collectively with the First Subsidiary Note,
the "Subsidiary Notes"; and the Parent Notes and Subsidiary Notes are
hereinafter sometimes collectively referred to as the "Notes").

      Alexander M. Milley, the Chairman, President and Chief Executive Officer
of both Parent and Subsidiary and a significant stockholder of Parent, is also
(i) the sole general partner of the Pledgor and the majority holder of the
partnership interests therein, and (ii) an officer and director of Cadmus and
the direct or indirect controlling stockholder thereof. Accordingly, each of
Parent, Subsidiary, Pledgor and Cadmus may be deemed to be under the common
control of Mr. Milley.

      The promissory notes that were respectively amended and restated by the
Notes had maturity dates earlier than, and certain other provisions less
favorable to the "Payors" thereunder than, those of the Notes. The Notes thus
represent financial accommodations provided by Parent and Subsidiary to Pledgor
and Cadmus. The Parent and Subsidiary were unwilling to provide such financial
accommodations without the pledges and grant of security interests hereunder by
Pledgor and the other representations, warranties covenants and agreements of
Pledgor provided hereunder.

      NOW, THEREFORE, for good and valuable consideration the receipt and
sufficiency of which are hereby acknowledged, the parties hereto hereby agree as
follows:

                                   Agreements

      1.    SECURITY FOR OBLIGATIONS. This Agreement is for (x) the senior
benefit of Parent as the holder of the Parent Notes, and (y) the subordinated
benefit of Subsidiary as the holder of the Subsidiary Notes to secure (i) the
full and prompt payment when due of all obligations and liabilities of Pledgor
to Parent arising under the Parent Notes (the "Senior Obligations"), and (ii)
the full and prompt payment when due of all obligations and liabilities of
Cadmus to Subsidiary arising under the Subsidiary Notes (the "Subordinated
Obligations"; and the Senior Obligations and the Subordinated Obligations being
collectively referred to herein as the "Obligations").
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      2.    GUARANTY OF CADMUS OBLIGATIONS. Pledgor hereby guarantees the
payment and performance of the Subordinated Obligations and waives, to the
extent legally permissible, all defenses available to a surety in connection
therewith.

      3.    PLEDGE AND GRANT OF SECURITY INTERESTS.

            3.1.  Pledge and Grant. (a) To secure on a (x) first priority basis
the Senior Obligations, and (y) second priority basis (subject only to the first
priority of the security for the Senior Obligations) the Subordinated
Obligations, THE PLEDGOR HEREBY: (i) grants to the Pledgee a security interest
in and to all of Pledgor's right, title and interest in, to and under the
Physical Securities, the Brokerage Accounts and all other Collateral (as such
terms are hereinafter defined), whether now owned or hereafter acquired by the
Pledgor; (ii) pledges and deposits as security with the Pledgee all of the
Pledgor's Physical Securities and delivers to the Pledgee the certificates
evidencing same, accompanied by stock power(s) duly executed in blank by the
Pledgor covering the same; (iii) with respect to the Pledgor's Brokerage
Account(s), executes and delivers to the Pledgee, for countersignature and
delivery to the financial intermediary maintaining the same, a Brokerage Account
Control Instruction letter in the form of Exhibit A (each, a "Control
Instruction"); and (iv) otherwise assigns, transfers, hypothecates, mortgages,
charges and sets over to the Pledgee all of the Pledgor's right, title and
interest in and to all Collateral, whether now owned or hereafter acquired by
the Pledgor, to be held by the Pledgee upon the terms and conditions set forth
in this Agreement.

                  (b)   It is understood and agreed by the parties hereto that:
(i) Subsidiary, as the holder of the Subordinated Obligations, shall not be
entitled to any distribution or payment arising from the enforcement of or other
realization upon the Collateral, and that no distribution or payment in any
bankruptcy, insolvency, reorganization or similar proceeding involving the
Pledgor made in respect of or in recognition of the security interests, pledges
and liens created hereunder in respect of the Collateral shall be applied to the
Subordinated Obligations or shall be for the benefit of Subsidiary as such
holder, until such time as the Senior Obligations shall have been irrevocably
paid in full in cash or cash equivalents; and (ii) the Pledgee shall take all
actions to enforce, realize upon and protect the security interests, pledges and
liens created hereunder in respect of the Collateral, and shall assert all
claims and make all filings under or in respect of any such bankruptcy,
insolvency, reorganization or similar proceeding, and that such actions and
claims shall be taken or made consistent with the priorities of the respective
Obligations established hereunder.

            3.2.  Subsequently Acquired Securities. If the Pledgor shall acquire
(by or through purchase, stock dividend, distribution of capital, any event
referred to in Section 6 hereof, or otherwise) any additional shares of capital
stock or other securities of Parent or Molecular Diagnostics, Inc., a Delaware
corporation ("MDI"), whether within or without any Brokerage Account, or of any
other issuer within the Brokerage Account, then the Pledgor will forthwith
pledge and deposit the same as security for all Obligations with the Pledgee and
deliver to the Pledgee (if available) certificates or instruments evidencing
same, accompanied by stock power(s) duly executed in blank by the Pledgor or
such other instruments of transfer as are acceptable to the Pledgee covering the
same.

            3.3.  Definitions of Pledged Securities and Collateral. Under this
Agreement, the:

                  (a)   "Physical Securities" means and includes the equity
securities identified on Schedule 1 hereto, if any, and the certificates
representing the same;

                  (b)   "Brokerage Accounts" means and includes the brokerage
account(s) identified on Schedule 1 hereto, if any, and all of the property,
assets, rights, entitlements deposited or held therein;

                  (c)   "Collateral" means and includes (i) the Physical
Securities (if any), (ii) the Brokerage Accounts (if any), (iii) any securities
or other property or assets pledged, deposited or delivered (or required to be

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pledged, deposited or delivered) under Section 3.2, Section 6 or any other
provision of this Agreement, and (iv) all products and proceeds of any of the
foregoing.

      4.    APPOINTMENT OF SUB-AGENTS; ENDORSEMENTS, ETC. The Pledgee shall have
the right to appoint one or more sub-agents for the purpose of retaining
physical possession of any Physical Securities delivered to the Pledgee
hereunder, which may be held (in the discretion of the Pledgee) in the name of
the Pledgor, endorsed or assigned in blank or in favor of the Pledgee or any
nominee or nominees of the Pledgee or a sub-agent appointed by the Pledgee.

      5.    VOTING, ETC., WHILE NO EVENT OF DEFAULT. Unless and until an Event
of Default (as defined below) shall have occurred and be continuing, the Pledgor
shall be entitled to exercise all voting rights attaching to any and all
Collateral, and to give consents, waivers or ratifications in respect thereof,
provided that no vote shall be cast or any consent, waiver or ratification given
or any action taken which would violate or be inconsistent with any of the terms
of this Agreement or which would have the effect of impairing the rights of the
Pledgee or any holder of the Obligations. All such rights of the Pledgor to vote
and to give consents, waivers and ratifications shall cease upon the occurrence
of an Event of Default which shall be continuing, and Section 7 hereof shall
thereupon become applicable.

      6.    DIVIDENDS AND OTHER DISTRIBUTIONS. All dividends and distributions
paid in respect of any of the Collateral shall be delivered to the Pledgee and
held as additional Collateral hereunder. The Pledgee shall also be entitled to
receive directly, and to retain as part of the Collateral: (a) all other or
additional stock or other securities or property paid or distributed by way of
dividend or otherwise in respect of any Collateral; (b) all other or additional
stock or other securities or property (including cash) paid or distributed in
respect of any Collateral by way of stock-split, spin-off, split-up,
reclassification, combination of shares or similar rearrangement; and (c) all
other or additional stock or other securities or property (including cash) which
may be paid in respect of any Collateral by reason of any consolidation, merger,
exchange of stock, conveyance of assets, liquidation or similar corporate
reorganization. Any and all such dividends, distributions, stock, securities or
other property (including cash) paid and deposited in any Brokerage Account
shall be retained and held in such Brokerage Account, subject to the terms of
the applicable Control Instructions.

      7.    EVENTS OF DEFAULT AND REMEDIES. (a) For purposes of this Agreement
it shall be an "Event of Default" if any event of default shall occur under any
of the Notes.

            (b)   If an Event of Default shall have occurred and be continuing,
the Pledgee shall be entitled to exercise all of the rights, powers and remedies
(whether vested in it by this Agreement, any Control Instructions or applicable
law) for the protection and enforcement of its rights in respect of the
Collateral, and the Pledgee shall be entitled, without limitation, to exercise
the following rights and remedies, which the Pledgor hereby agrees to be
commercially reasonable:

                  (i)   to transfer all or any part of the Physical Securities,
Brokerage Accounts or other Collateral into the Pledgee's name or the name of
its nominee or nominees;

                  (ii)  to exercise all voting rights attaching to all or any
part of the Collateral (whether or not transferred into the name of the Pledgee)
and give all consents, waivers and ratifications in respect of the Collateral
and otherwise act with respect thereto as though it were the outright owner
thereof (the Pledgor hereby irrevocably constituting and appointing the Pledgee
the proxy and attorney-in-fact of the Pledgor, with full power of substitution
to do so);

                  (iii) with respect to the Brokerage Account(s), to otherwise
exercise full dominion and control thereof, to the exclusion of Pledgor and
other persons, including the right to liquidate and receive the proceeds of such
liquidation;

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                  (iv)  with respect to any securities or any other property
included in the Collateral (including any such securities held in any Brokerage
Account), to take and apply the same as payment on account of the Obligations
provided that in the event of such application the outstanding Obligations shall
be reduced based on the fair value thereof as determined in good faith by the
Board of Directors of Pledgee; and

                  (v)   at any time or from time to time to sell, assign and
deliver, or grant options to purchase, all or any part of the Collateral
(including Collateral held in any Brokerage Account), or any interest therein,
at any public or private sale, without demand of performance, advertisement or
notice of intention to sell or of the time or place of sale or adjournment
thereof or to redeem or otherwise (all of which are hereby waived by the
Pledgor), for cash, on credit or for other property, for immediate or future
delivery without any assumption of credit risk, and for such price or prices and
on such terms as the Pledgee in its absolute discretion may determine, provided
that at least 10 days' notice of the time and place of any such sale shall be
given to the Pledgor.

            (c)   The Pledgor hereby waives and releases to the fullest extent
permitted by law any right or equity of redemption with respect to the
Collateral, whether before or after sale hereunder, and all rights, if any, of
marshalling the Collateral and any other security for the Obligations or
otherwise. At any such sale, unless prohibited by applicable law, the Pledgee
may bid for and purchase all or any part of the Collateral so sold free from any
such right or equity of redemption. The Pledgee shall not be liable for failure
to collect or realize upon any or all of the Collateral or for any delay in so
doing nor shall it be under any obligation to take any action whatsoever with
regard thereto.

      8.    REMEDIES, ETC., CUMULATIVE. Each right, power and remedy of the
Pledgee provided for in this Agreement, the Control Instructions or now or
hereafter existing at law or in equity or by statute shall be cumulative and
concurrent and shall be in addition to every other such right, power or remedy.
The exercise or beginning of the exercise by the Pledgee of any one or more of
the rights, powers or remedies provided for in this Agreement or now or
hereafter existing at law or in equity or by statute or otherwise shall not
preclude the simultaneous or later exercise by the Pledgee of all such other
rights, powers or remedies, and no failure or delay on the part of the Pledgee
to exercise any such right, power or remedy shall operate as a waiver thereof.

      9.    APPLICATION OF PROCEEDS. (a) All moneys collected by the Pledgee
upon any sale, application or other disposition of Collateral through
enforcement, realization hereunder or otherwise, together with all other moneys
received by the Pledgee hereunder in respect of Collateral, shall first be
applied to the payment of all costs and expenses incurred by the Pledgee in
connection with such sale or disposition, the delivery of the Collateral or the
collection of any such moneys (including, without limitation, reasonable
attorneys' fees and expenses), and the balance of such moneys (the "Remaining
Proceeds") shall be applied by the Pledgee as required below.

            (b)   Prior to the satisfaction in full of the Senior Obligations,
the Remaining Proceeds shall be applied, when available, to satisfy, in full,
the Senior Obligations. Where the Remaining Proceeds are insufficient to pay off
the Senior Obligations in full, such Remaining Proceeds will be applied (i)
first, to the unpaid and accrued interest on the Parent Notes, (ii) second, to
the unpaid principal amount of the Parent Notes, and (iii) third, to any other
obligations owed under the Parent Notes.

            (c)   After the satisfaction in full of the Senior Obligations, any
Remaining Proceeds not theretofore distributed pursuant to the foregoing
provisions of this Section 9 shall be applied, when available, to satisfy, in
full, the Subordinated Obligations. Where the Remaining Proceeds are
insufficient for the payment in full of the outstanding Subordinated
Obligations, the amounts received shall be applied (i) first, to the unpaid and
accrued interest on the Cadmus Notes, (ii) second, to the unpaid principal
amount of the Cadmus Notes, and (iii) third, to any other obligations owed under
the Cadmus Notes.

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      10.   PURCHASERS OF COLLATERAL. Upon any sale of the Collateral by the
Pledgee hereunder (whether by virtue of the power of sale herein granted,
pursuant to judicial process or otherwise), the receipt of the Pledgee or the
officer making the sale shall be a sufficient discharge to the purchaser or
purchasers of the Collateral so sold, and such purchaser or purchasers shall not
be obligated to see to the application of any part of the purchase money paid
over to the Pledgee or such officer or be answerable in any way for the
misapplication or nonapplication thereof.

      11.   INDEMNITY. The Pledgor agrees to indemnify and hold harmless the
Pledgee (as such), Parent and Subsidiary from and against any and all claims,
demands, losses, judgments and liabilities (including liabilities for penalties)
of whatsoever kind or nature, and to reimburse the Pledgee, Parent and
Subsidiary for all costs and expenses, including reasonable attorneys' fees,
growing out of or resulting from this Agreement or the exercise by the Pledgee
of any right or remedy granted to it hereunder. In no event shall the Pledgee be
liable, in the absence of gross negligence or willful misconduct on its part,
for any matter or thing in connection with this Agreement or the Control
Instructions other than to account for moneys actually received by it in
accordance with the terms hereof. If and to the extent that the obligations of
the Pledgor under this Section 11 are unenforceable for any reason, the Pledgor
hereby agrees to make the maximum contribution to the payment and satisfaction
of such obligations which is permissible under applicable law.

      12.   FURTHER ASSURANCES. The Pledgor agrees that it will join with the
Pledgee in executing and, at its own expense, file and refile under the Uniform
Commercial Code such financing statements, continuation statements and other
documents in such offices as the Pledgee may deem necessary or appropriate and
wherever required or permitted by law in order to perfect and preserve the
Pledgee's security interest in the Collateral and hereby authorizes the Pledgee
to file financing statements and amendments thereto relative to all or any part
of the Collateral without the signature of the Pledgor where permitted by law,
and agrees to do such further acts and things and to execute and deliver to the
Pledgee such additional conveyances, assignments, agreements and instruments as
the Pledgee may reasonably require or deem advisable to carry into effect the
purposes of this Agreement or to further assure and confirm unto the Pledgee its
rights, powers and remedies hereunder.

      13.   THE PLEDGEE AS AGENT. The Pledgee will hold in accordance with this
Agreement and any applicable Control Instructions all items of the Collateral at
any time received under this Agreement or any applicable Control Instructions.
It is expressly understood and agreed that the obligations of the Pledgee as
holder of the Collateral and interests therein and with respect to the
disposition thereof, and otherwise under this Agreement or any applicable
Control Instructions, are only those expressly set forth herein or therein.

      14.   REPRESENTATIONS, WARRANTIES, COVENANTS AND AGREEMENTS OF THE
PLEDGOR. The Pledgor hereby represents and warrants that (a) if it is not a
natural person, it is a corporation, partnership or limited liability company
duly organized and validly existing in good standing under the laws of the state
of its organization; (b) it is the legal and/or beneficial owner of the
Collateral and has good title thereto, subject to no pledge, lien, mortgage,
hypothecation, security interest, charge, option or other encumbrance
whatsoever, except the liens and security interests created or contemplated by
this Agreement and, with respect to any Brokerage Accounts (and any Collateral
deposited therein), any applicable agreements with or liens in favor of any
financial intermediaries holding or maintaining the same; (c) it has the power,
authority and legal right to pledge and grant security interests in the
Collateral pursuant to this Agreement; (d) this Agreement and any Control
Instructions to which it is a party have been duly executed and delivered by the
Pledgor and constitutes the legal, valid and binding obligation of the Pledgor
enforceable against the Pledgor in accordance with their respective terms
(subject to limitations as to enforceability which might result from bankruptcy,
insolvency or other laws affecting creditors' rights generally and general
principles of equity); (e) no consent of any other party and no consent,
license, permit, approval or authorization of, exemption by, notice or report
to, or registration, filing or declaration with, any court or governmental
agency is required to be obtained by the Pledgor in connection with the
execution, delivery or performance of this Agreement or the Control
Instructions; (f) the execution, delivery and performance of this Agreement and
the Control Instructions to which it is a party will not violate any provision

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of any applicable law or regulation or of any order, judgment, writ, award or
decree of any court, arbitrator or governmental authority, domestic or foreign,
or of the certificate or articles of incorporation or formation, or the by-laws,
or the operating or partnership agreement (as applicable) of the Pledgor, or of
any mortgage, indenture, lease, contract or other agreement, instrument or
undertaking to which the Pledgor is a party or which purports to be binding upon
the Pledgor except as contemplated by this Agreement; and (g) the security
interest in the Collateral hereunder is a valid and perfected first priority
security interest therein securing the Obligations, subject to no prior lien or
encumbrance or to any agreement purporting to grant to any third party a lien or
encumbrance on the property or assets of the Pledgor which would include any of
the Collateral subject to, in the case of any Brokerage Accounts (and any
Collateral deposited therein), any applicable agreements with or liens in favor
of any financial intermediaries holding or maintaining the same. The Pledgor
covenants and agrees that: (i) the Pledgor not sell, assign, transfer, exchange,
or otherwise dispose of, or grant any option with respect to, any of the
Collateral, (ii) the Pledgor shall not create, incur or permit to exist any lien
or option in favor of, or any claim of any person with respect to, any of the
Collateral, or any interest therein, except for the liens provided for or
contemplated by this Agreement whatsoever, except the liens and security
interests created or contemplated by this Agreement and, with respect to any
Brokerage Accounts (and any Collateral deposited therein), any applicable
agreements with or liens in favor of any financial intermediaries holding or
maintaining the same, (iii) the Pledgor will defend the Pledgee's right, title
and security interest in and to the Collateral against the claims and demands of
all persons and entities whomsoever (except as aforesaid); and (iv) the Pledgor
will have like title to and the right to pledge and grant a security interest in
any other property at any time hereafter included in the Collateral hereunder
and will likewise defend the right thereto and security interest therein of the
Pledgee. The Pledgor further covenants and agrees to pay, and to save the
Pledgee, Parent and Subsidiary harmless from, any and all liabilities with
respect to, or resulting from any delay in paying, any and all stamps, excise,
sales or other taxes which may be payable or determined to be payable with
respect to any of the Collateral or in connection with any of the transactions
contemplated by this Agreement.

      15.   PLEDGOR'S OBLIGATIONS ABSOLUTE, ETC. The obligations of the Pledgor
under this Agreement shall be absolute and unconditional and shall remain in
full force and effect without regard to, and shall not be released, suspended,
discharged, terminated or otherwise affected by, any circumstance or occurrence
whatsoever, including, without limitation: (a) any renewal, extension, amendment
or modification of or addition or supplement to or deletion from all or any of
the Notes or Obligations, or any assignment or transfer thereof; (b) any waiver,
consent, extension, indulgence or other action or inaction under or in respect
of all or any of the Notes, Obligations or this Agreement; (c) any furnishing of
any additional security to the Pledgee, Parent, Subsidiary or any of their
respective assignees, or any acceptance thereof, or any release of any security
by the Pledgee, Parent, Subsidiary or any of their respective assignees; (d) any
limitation on any party's liability or obligations under any or all of the
Notes, Obligations, this Agreement or additional security agreement(s), or any
invalidity or unenforceability, in whole or in part, of any of the foregoing; or
(e) any bankruptcy, insolvency, reorganization, composition, adjustment,
dissolution, liquidation or other like proceeding relating to any obligor with
respect to any of the Obligations, or any action taken with respect to this
Agreement by any trustee or receiver, or by any court, in any such proceeding,
whether or not the Pledgor shall have notice or knowledge of any of the
foregoing.

      16.   REGISTRATION, ETC. (a) If an Event of Default shall have occurred
and be continuing and the Pledgor shall have received from the Pledgee a written
request or requests that the Pledgor cause any registration, qualification or
compliance under any Federal or state securities law or laws to be effected with
respect to all or any part of the collateral consisting of equity securities
issued by Parent or MDI (the "Pledged Securities"), the Pledgor as soon as
practicable and at its expense will use its reasonable efforts to cause such
registration to be effected (and be kept effective) and will use its reasonable
efforts to cause such qualification and compliance to be effected (and be kept
effective) as may be so requested and as would permit or facilitate the sale and
distribution of such Pledged Securities, including, without limitation,
registration under the Securities Act of 1933 as then in effect (or any similar
statute then in effect), appropriate qualifications under applicable blue sky or
other state securities laws and appropriate compliance with any other government

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requirements, provided, that the Pledgee shall furnish to the Pledgor such
information regarding the Pledgee as the Pledgor may request in writing and as
shall be required in connection with any such registration, qualification or
compliance. The Pledgor will cause the Pledgee to be kept reasonably advised in
writing as to the progress of each such registration, qualification or
compliance and as to the completion thereof, will furnish to the Pledgee such
number of prospectuses, offering circulars or other documents incident thereto
as the Pledgee from time to time may reasonably request, and will indemnify the
Pledgee, Parent and Subsidiary and all others participating in the distribution
of such Pledged Securities against all claims, losses, damages and liabilities
caused by any untrue statement (or alleged untrue statement) of a material fact
contained therein (or in any related registration statement, notification or the
like) or by any omission (or alleged omission) to state therein (or in any
related registration statement, notification or the like) a material fact
required to be stated therein or necessary to make the statements therein not
misleading, except insofar as the same may have been caused by an untrue
statement or omission based upon information furnished in writing to the Pledgor
by the Pledgee expressly for use therein.

            (b)   If at any time when the Pledgee shall determine to exercise
its right to sell all or any part of the Pledged Securities pursuant to Section
7, and such Pledged Securities or the part thereof to be sold shall not, for any
reason whatsoever, be effectively registered under the Securities Act of 1933,
as then in effect, the Pledgee may, in its sole and absolute discretion, sell
such Pledged Securities or part thereof by private sale in such manner and under
such circumstances as Pledgee may deem necessary or advisable in order that such
sale may legally be effected without such registration, provided that at least
10 days' notice of the time and place of any such sale shall be given to the
Pledgor. Without limiting the generality of the foregoing, in any such event the
Pledgee, in its sole and absolute discretion (i) may proceed to make such
private sale notwithstanding that a registration statement for the purpose of
registering such Pledged Securities or part thereof shall have been filed under
such Act, (ii) may approach and negotiate with a single possible purchaser to
effect such sale, and (iii) may restrict such sale to a purchaser who will
represent and agree that such purchaser is purchasing for its own account, for
investment, and not with a view to the distribution or sale of such Pledged
Securities or part thereof. In the event of any such sale, the Pledgee shall
incur no responsibility or liability for selling all or any part of the Pledged
Securities at a price which the Pledgee, in its sole and absolute discretion,
may in good faith deem reasonable under the circumstances, notwithstanding the
possibility that a substantially higher price might be realized if the sale were
deferred until after registration as aforesaid.

      17.   THE PLEDGOR'S RELEASE OF PLEDGEE. Under no circumstances shall
Pledgee, Parent or Subsidiary be deemed to assume any responsibility for or
liability, obligation or duty with respect to any part or all of the Pledged
Securities, Brokerage Accounts or other Collateral of any nature or kind or any
matter or proceeding arising out of or related thereto, except as required by
applicable law. Pledgee shall not be required to take any action of any kind to
collect, preserve or protect its or the Pledgor's rights in the Collateral, or
against other persons or entities. The Pledgor hereby releases Pledgee, Parent
and Subsidiary from any claims, causes of action and demands with respect to the
Collateral or any actions taken or omitted to be taken by Pledgee with respect
thereto so long as such actions which relate to the custody and preservation of
the Collateral in Pledgee's possession are taken or omitted to be taken with
reasonable care, and the Pledgor hereby agrees to hold Pledgee harmless from and
with respect to any and all such claims, causes of action and demands.
Nevertheless, Pledgee agrees to exercise reasonable care in the physical
preservation of the Collateral in its actual possession.

      18.   TERMINATION. Upon the payment and performance in full of all of the
Obligations, this Agreement shall terminate, all Control Instructions shall
terminate, and such of the Collateral as have not theretofore been sold or
otherwise applied pursuant to the terms of this Agreement shall be delivered to
the Pledgor or as the Pledgor may direct in writing.

      19.   NOTICES. All notices, requests, demands, directions, consents or
waivers, statements, reports and other communications hereunder shall be deemed
to have been given when mailed by first-class, registered or certified mail
(postage prepaid) or transmitted by telecopier to the applicable party or
parties.

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      20.   GENERAL. This Agreement shall bind and inure to the benefit of the
respective successors and permitted assigns of the parties hereto. Neither this
Agreement nor the obligations of the Pledgor hereunder may be assigned or
delegated by the Pledgor without the prior written consent of the Pledgee. This
Agreement may not be changed orally, but only by an instrument in writing signed
by the person against whom enforcement of such change, modification or discharge
is sought.

      21.   SEVERABILITY. If any word, phrase, sentence, paragraph, provision or
section of this Agreement shall be held, declared, pronounced or rendered
invalid, void, unenforceable or inoperative for any reason by any court of
competent jurisdiction, governmental authority, statute, or otherwise, such
holding, declaration, pronouncement or rendering shall not adversely affect any
other word, phrase, sentence, paragraph, provision or section of this Agreement,
which shall otherwise remain in full force and effect and be enforced in
accordance with its terms, provided such holding, declaration, pronouncement or
rendering does not release the Pledged Securities or other Collateral from the
pledge or security interest hereunder or result in or permit a prior lien on the
Pledged Securities or other Collateral or adversely affect Pledgee's rights upon
an Event of Default to transfer and vote, and in compliance with law, sell, the
Pledged Securities. Any other holding, declaration, pronouncement or rendering
of any word, phrase, sentence, paragraph, provision or section of this Agreement
as invalid, void, unenforceable or inoperative shall constitute an Event of
Default under section 2 of the Notes.

      22.   GOVERNING LAW. THIS AGREEMENT SHALL BE GOVERNED BY, AND CONSTRUED IN
ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW YORK.

      23.   COUNTERPARTS. This Agreement may be executed in any number of
counterparts, each of which for all purposes shall be deemed to be an original.

      IN WITNESS WHEREOF, the parties hereto have caused this Pledge Agreement
to be executed as of the day and year first above written.

ELX LIMITED PARTNERSHIP                ELXSI CORPORATION,
as Pledgor                             as Pledgee

By: /s/ ALEXANDER M. MILLEY            By: /s/ DAVID M. DOOLITTLE
    ----------------------------           ---------------------------
    Alexander M. Milley                    David M. Doolittle
    Title: Sole General Partner            Title: Vice President & Chief
                                                  Financial Officer

                                        8
<PAGE>

                                   Schedule 1
                                   ----------

                               Initial Collateral
                               ------------------

1.    Physical Securities
      -------------------

None.

2.    Brokerage Accounts
      ------------------

N.B. Zoullas Securities, Inc. Account No. 663-00131, in which there is currently
deposited 590,200 shares of Common Stock of Parent.
<PAGE>

                                    Exhibit A
                                    ---------

                  Form of Brokerage Account Control Instruction
                  ---------------------------------------------

                                  [Letterhead]

N.B. Zoullas Securities, Inc.
909 3rd Avenue, 29th Floor
New York, NY  10022

                                                                  April __, 2002

                              Account No. xxx-xxxxx
                              ---------------------

Ladies and Gentlemen:

      The undersigned ("Account Holder") has granted to ELXSI Corporation, a
Delaware corporation ("Secured Party"), a security interest in and to the
Account Holder's N.B. Zoullas Securities, Inc. brokerage account numbered
xxx-xxxxx (the "Account"). The purpose of this letter is to help perfect the
Secured Party's security interest in the Account by granting it certain control
over the Account and any securities, cash or other property held therein, as
hereinafter provided.

      You are hereby instructed by the Account Holder that:

1.    You may not authorize or engage in any trading or other activity in or
      with respect to the Account, or any securities, cash or other property
      held therein, unless and to the extent jointly instructed in writing by
      both the Account Holder and the Secured Party. However, from and after
      your receipt of written advice from the Secured Party to the effect that
      an "Event of Default" has occurred and is continuing with respect to the
      Account Holder (a "Default Notice"), the Account Holder shall no longer
      have any authorization with respect to such trading and other activity,
      and shall thereupon accept and act upon only the instructions of the
      Secured Party.

2.    Notwithstanding the foregoing, until such time (if any) as you shall have
      received a Default Notice, the Account Holder shall have full authority to
      give you directions with respect to any voting of any securities held in
      the Account.

3.    From and after your receipt of a Default Notice, the Secured Party shall
      have the full power and authority (to the exclusion of the Account
      Holder), to exercise dominion and control over the Account (subject to the
      applicable Account agreement(s) and restrictions), including (without
      limitation) the right to liquidate the account and/or to transfer the
      entire account position to an existing or new account established in the
      name of the Secured Party.

      The foregoing instructions shall remain effective and in full force and
effect until such time (if any) that the Secured Party (with or without the
Account Holder) shall advise you in writing that the security interest referred
to hereinabove shall have been terminated.

                                   Very truly yours,
                                   ELX Limited Partnership

                                   By: /s/ ALEXANDER M. MILLEY
                                       -----------------------------------------
                                       Alexander M. Milley, Sole General Partner

Acknowledged and accepted
ELXSI Corporation

By: /s/ DAVID M. DOOLITTLE
    ----------------------------------------
    David M. Doolittle
    Vice President & Chief Financial Officer

                                        2Exhibit 10.41

                          PLEDGE AND SECURITY AGREEMENT

      PLEDGE AND SECURITY AGREEMENT, dated as of December 31, 2001 (this
"Agreement"), between (1) Cadmus Corporation, a Massachusetts corporation (the
"Pledgor"), and (2) ELXSI CORPORATION, a Delaware corporation ("Parent"), as
collateral agent (the "Pledgee"), for the benefit of (i) on a first priority
basis, ELXSI, a California corporation ("Subsidiary") and wholly owned
subsidiary of Parent, as the holder of the Subsidiary Notes (as defined below),
and (ii) on a second priority basis, Parent as the holder of the Parent Notes
(as defined below).

                                   Background

      Pledgor is the "Payor" under that certain: (i) Amended and Restated
$2,000,000 Secured Promissory Note, dated as of December 31, 2001 and due April
1, 2005, payable to Subsidiary (the "First Subsidiary Note"), and (ii) Amended
and Restated $7,003,364 Promissory Note, dated as of December 31, 2001 and due
April 1, 2005, payable to Subsidiary (the "Second Subsidiary Note"; and
collectively with the First Subsidiary Note, the "Subsidiary Notes").

      ELX Limited Partnership, a Delaware limited partnership ("ELXLP") is the
"Payor" under that certain: (i) Amended and Restated Promissory Note, dated as
of December 31, 2001 and due April 1, 2005, payable to Parent and having an
original principal amount of $1,606,278 (the "First Parent Note"), and (ii)
Amended and Restated Promissory Note, dated as of December 31, 2001 and due
April 1, 2005, payable to Parent and having an original principal amount of
$1,362,489 (the "Second Parent Note"; and collectively with the First Parent
Note, the "Parent Notes"; and the Parent Notes and Subsidiary Notes are
hereinafter sometimes collectively referred to as the "Notes").

      Alexander M. Milley, the Chairman, President and Chief Executive Officer
of both Parent and Subsidiary and a significant stockholder of Parent, is also
(i) the sole general partner of ELXLP and the majority holder of the partnership
interests therein, and (ii) an officer and director of Pledgor and the direct or
indirect controlling stockholder thereof. Accordingly, each of Parent,
Subsidiary, Pledgor and ELXLP may be deemed to be under the common control of
Mr. Milley.

      The promissory notes that were respectively amended and restated by the
Notes had maturity dates earlier than, and certain other provisions less
favorable to the "Payors" thereunder than, those of the Notes. The Notes thus
represent financial accommodations provided by Parent and Subsidiary to Pledgor
and ELXLP. The Parent and Subsidiary were unwilling to provide such financial
accommodations without the pledges and grant of security interests hereunder by
Pledgor and the other representations, warranties covenants and agreements of
Pledgor provided hereunder.

      NOW, THEREFORE, for good and valuable consideration the receipt and
sufficiency of which are hereby acknowledged, the parties hereto hereby agree as
follows:

                                   Agreements

      1.    SECURITY FOR OBLIGATIONS. This Agreement is for (x) the senior
benefit of Subsidiary as the holder of the Subsidiary Notes, and (y) the
subordinated benefit of Parent as the holder of the Parent Notes to secure (i)
the full and prompt payment when due of all obligations and liabilities of
Pledgor to Subsidiary arising under the Subsidiary Notes (the "Senior
Obligations"), and (ii) the full and prompt payment when due of all obligations
and liabilities of ELXLP to Parent arising under the Parent Notes (the
"Subordinated Obligations"; and the Senior Obligations and the Subordinated
Obligations being collectively referred to herein as the "Obligations").
<PAGE>

      2.    GUARANTY OF ELXLP OBLIGATIONS. Pledgor hereby guarantees the payment
and performance of the Subordinated Obligations and waives, to the extent
legally permissible, all defenses available to a surety in connection therewith.

      3.    PLEDGE AND GRANT OF SECURITY INTERESTS.

            3.1.  Pledge and Grant. (a) To secure on a (x) first priority basis
the Senior Obligations, and (y) second priority basis (subject only to the first
priority of the security for the Senior Obligations) the Subordinated
Obligations, THE PLEDGOR HEREBY: (i) grants to the Pledgee a security interest
in and to all of Pledgor's right, title and interest in, to and under the
Physical Securities, the Brokerage Accounts and all other Collateral (as such
terms are hereinafter defined), whether now owned or hereafter acquired by the
Pledgor; (ii) pledges and deposits as security with the Pledgee all of the
Pledgor's Physical Securities and delivers to the Pledgee the certificates
evidencing same, accompanied by stock power(s) duly executed in blank by the
Pledgor covering the same; (iii) with respect to the Pledgor's Brokerage
Account(s), executes and delivers to the Pledgee, for countersignature and
delivery to the financial intermediary maintaining the same, a Brokerage Account
Control Instruction letter in the form of Exhibit A (each, a "Control
Instruction"); and (iv) otherwise assigns, transfers, hypothecates, mortgages,
charges and sets over to the Pledgee all of the Pledgor's right, title and
interest in and to all Collateral, whether now owned or hereafter acquired by
the Pledgor, to be held by the Pledgee, upon the terms and conditions set forth
in this Agreement.

                  (b)   It is understood and agreed by the parties hereto that:
(i) Subsidiary, as the holder of the Subordinated Obligations, shall not be
entitled to any distribution or payment arising from the enforcement of or other
realization upon the Collateral, and that no distribution or payment in any
bankruptcy, insolvency, reorganization or similar proceeding involving the
Pledgor made in respect of or in recognition of the security interests, pledges
and liens created hereunder in respect of the Collateral shall be applied to the
Subordinated Obligations or shall be for the benefit of Subsidiary as such
holder, until such time as the Senior Obligations shall have been irrevocably
paid in full in cash or cash equivalents; and (ii) the Pledgee shall take all
actions to enforce, realize upon and protect the security interests, pledges and
liens created hereunder in respect of the Collateral, and shall assert all
claims and make all filings under or in respect of any such bankruptcy,
insolvency, reorganization or similar proceeding, and that such actions and
claims shall be taken or made consistent with the priorities of the respective
Obligations established hereunder.

            3.2.  Subsequently Acquired Securities. If the Pledgor shall acquire
(by or through purchase, stock dividend, distribution of capital, any event
referred to in Section 6 hereof, or otherwise) any additional shares of capital
stock or other securities of Parent or Molecular Diagnostics, Inc., a Delaware
corporation ("MDI"), whether within or without any Brokerage Account, or of any
other issuer within the Brokerage Account, then the Pledgor will forthwith
pledge and deposit the same as security for all Obligations with the Pledgee and
deliver to the Pledgee (if available) certificates or instruments evidencing
same, accompanied by stock power(s) duly executed in blank by the Pledgor or
such other instruments of transfer as are acceptable to the Pledgee covering the
same.

            3.3.  Definitions of Pledged Securities and Collateral. Under this
Agreement, the:

                  (a)   "Physical Securities" means and includes the equity
securities identified on Schedule 1 hereto, if any, and the certificates
representing the same;

                  (b)   "Brokerage Accounts" means and includes the brokerage
account(s) identified on Schedule 1 hereto, if any, and all of the property,
assets, rights, entitlements deposited or held therein;

                  (c)   "Collateral" means and includes (i) the Physical
Securities (if any), (ii) the Brokerage Accounts (if any), (iii) any securities
or other property or assets pledged, deposited or delivered (or required to be
pledged, deposited or delivered) under Section 3.2, Section 6 or any other
provision of this Agreement, and (iv) all products and proceeds of any of the
foregoing.

                                       -2-
<PAGE>

      4.    APPOINTMENT OF SUB-AGENTS; ENDORSEMENTS, ETC. The Pledgee shall have
the right to appoint one or more sub-agents for the purpose of retaining
physical possession of any Physical Securities delivered to the Pledgee
hereunder, which may be held (in the discretion of the Pledgee) in the name of
the Pledgor, endorsed or assigned in blank or in favor of the Pledgee or any
nominee or nominees of the Pledgee or a sub-agent appointed by the Pledgee.

      5.    VOTING, ETC., WHILE NO EVENT OF DEFAULT. Unless and until an Event
of Default (as defined below) shall have occurred and be continuing, the Pledgor
shall be entitled to exercise all voting rights attaching to any and all
Collateral, and to give consents, waivers or ratifications in respect thereof,
provided that no vote shall be cast or any consent, waiver or ratification given
or any action taken which would violate or be inconsistent with any of the terms
of this Agreement or which would have the effect of impairing the rights of the
Pledgee or any holder of the Obligations. All such rights of the Pledgor to vote
and to give consents, waivers and ratifications shall cease upon the occurrence
of an Event of Default which shall be continuing, and Section 7 hereof shall
thereupon become applicable.

      6.    DIVIDENDS AND OTHER DISTRIBUTIONS. All dividends and distributions
paid in respect of any of the Collateral shall be delivered to the Pledgee and
held as additional Collateral hereunder. The Pledgee shall also be entitled to
receive directly, and to retain as part of the Collateral: (a) all other or
additional stock or other securities or property paid or distributed by way of
dividend or otherwise in respect of any Collateral; (b) all other or additional
stock or other securities or property (including cash) paid or distributed in
respect of any Collateral by way of stock-split, spin-off, split-up,
reclassification, combination of shares or similar rearrangement; and (c) all
other or additional stock or other securities or property (including cash) which
may be paid in respect of any Collateral by reason of any consolidation, merger,
exchange of stock, conveyance of assets, liquidation or similar corporate
reorganization. Any and all such dividends, distributions, stock, securities or
other property (including cash) paid and deposited in any Brokerage Account
shall be retained and held in such Brokerage Account, subject to the terms of
the applicable Control Instructions.

      7.    EVENTS OF DEFAULT AND REMEDIES. (a) For purposes of this Agreement
it shall be an "Event of Default" if any event of default shall occur under any
of the Notes.

            (b)   If an Event of Default shall have occurred and be continuing,
the Pledgee shall be entitled to exercise all of the rights, powers and remedies
(whether vested in it by this Agreement, any Control Instructions or applicable
law) for the protection and enforcement of its rights in respect of the
Collateral, and the Pledgee shall be entitled, without limitation, to exercise
the following rights and remedies, which the Pledgor hereby agrees to be
commercially reasonable:

                  (i)   to transfer all or any part of the Physical Securities,
Brokerage Accounts or other Collateral into the Pledgee's name or the name of
its nominee or nominees;

                  (ii)  to exercise all voting rights attaching to all or any
part of the Collateral (whether or not transferred into the name of the Pledgee)
and give all consents, waivers and ratifications in respect of the Collateral
and otherwise act with respect thereto as though it were the outright owner
thereof (the Pledgor hereby irrevocably constituting and appointing the Pledgee
the proxy and attorney-in-fact of the Pledgor, with full power of substitution
to do so);

                  (iii) with respect to the Brokerage Account(s), to otherwise
exercise full dominion and control thereof, to the exclusion of Pledgor and
other persons, including the right to liquidate and receive the proceeds of such
liquidation;

                  (iv)  with respect to securities or any other property,
included in the Collateral (including any such securities held in any Brokerage
Account), to take and apply the same as payment on account of the Obligations,

                                       -3-
<PAGE>

provided that in the event of such application the outstanding Obligations shall
be reduced based on the fair value thereof as determined in good faith by the
Board of Directors of Pledgee; and

                  (v)   at any time or from time to time to sell, assign and
deliver, or grant options to purchase, all or any part of the Collateral
(including Collateral held in any Brokerage Account), or any interest therein,
at any public or private sale, without demand of performance, advertisement or
notice of intention to sell or of the time or place of sale or adjournment
thereof or to redeem or otherwise (all of which are hereby waived by the
Pledgor), for cash, on credit or for other property, for immediate or future
delivery without any assumption of credit risk, and for such price or prices and
on such terms as the Pledgee in its absolute discretion may determine, provided
that at least 10 days' notice of the time and place of any such sale shall be
given to the Pledgor.

            (c)   The Pledgor hereby waives and releases to the fullest extent
permitted by law any right or equity of redemption with respect to the
Collateral, whether before or after sale hereunder, and all rights, if any, of
marshalling the Collateral and any other security for the Obligations or
otherwise. At any such sale, unless prohibited by applicable law, the Pledgee
may bid for and purchase all or any part of the Collateral so sold free from any
such right or equity of redemption. The Pledgee shall not be liable for failure
to collect or realize upon any or all of the Collateral or for any delay in so
doing nor shall it be under any obligation to take any action whatsoever with
regard thereto.

      8.    REMEDIES, ETC., CUMULATIVE. Each right, power and remedy of the
Pledgee provided for in this Agreement, the Control Instructions or now or
hereafter existing at law or in equity or by statute shall be cumulative and
concurrent and shall be in addition to every other such right, power or remedy.
The exercise or beginning of the exercise by the Pledgee of any one or more of
the rights, powers or remedies provided for in this Agreement or now or
hereafter existing at law or in equity or by statute or otherwise shall not
preclude the simultaneous or later exercise by the Pledgee of all such other
rights, powers or remedies, and no failure or delay on the part of the Pledgee
to exercise any such right, power or remedy shall operate as a waiver thereof.

      9.    APPLICATION OF PROCEEDS. (a) All moneys collected by the Pledgee
upon any sale, application or other disposition of Collateral through
enforcement, realization hereunder or otherwise, together with all other moneys
received by the Pledgee hereunder in respect of Collateral, shall first be
applied to the payment of all costs and expenses incurred by the Pledgee in
connection with such sale or disposition, the delivery of the Collateral or the
collection of any such moneys (including, without limitation, reasonable
attorneys' fees and expenses), and the balance of such moneys (the "Remaining
Proceeds") shall be applied by the Pledgee as required below.

            (b)   Prior to the satisfaction in full of the Senior Obligations,
the Remaining Proceeds shall be applied, when available, to satisfy, in full,
the Senior Obligations. Where the Remaining Proceeds are insufficient to pay off
the Senior Obligations in full, such Remaining Proceeds will be applied (i)
first, to the unpaid and accrued interest on the Parent Notes, (ii) second, to
the unpaid principal amount of the Parent Notes, and (iii) third, to any other
obligations owed under the Parent Notes.

            (c)   After the satisfaction in full of the Senior Obligations, any
Remaining Proceeds not theretofore distributed pursuant to the foregoing
provisions of this Section 9 shall be applied, when available, to satisfy, in
full, the Subordinated Obligations. Where the Remaining Proceeds are
insufficient for the payment in full of the outstanding Subordinated
Obligations, the amounts received shall be applied (i) first, to the unpaid and
accrued interest on the Cadmus Notes, (ii) second, to the unpaid principal
amount of the Cadmus Notes, and (iii) third, to any other obligations owed under
the Cadmus Notes.

      10.   PURCHASERS OF COLLATERAL. Upon any sale of the Collateral by the
Pledgee hereunder (whether by virtue of the power of sale herein granted,
pursuant to judicial process or otherwise), the receipt of the Pledgee or the
officer making the sale shall be a sufficient discharge to the purchaser or
purchasers of the Collateral so sold, and such purchaser or purchasers shall not

                                       -4-
<PAGE>

be obligated to see to the application of any part of the purchase money paid
over to the Pledgee or such officer or be answerable in any way for the
misapplication or nonapplication thereof.

      11.   INDEMNITY. The Pledgor agrees to indemnify and hold harmless the
Pledgee (as such), Parent and Subsidiary from and against any and all claims,
demands, losses, judgments and liabilities (including liabilities for penalties)
of whatsoever kind or nature, and to reimburse the Pledgee, Parent and
Subsidiary for all costs and expenses, including reasonable attorneys' fees,
growing out of or resulting from this Agreement or the exercise by the Pledgee
of any right or remedy granted to it hereunder. In no event shall the Pledgee be
liable, in the absence of gross negligence or willful misconduct on its part,
for any matter or thing in connection with this Agreement or the Control
Instructions other than to account for moneys actually received by it in
accordance with the terms hereof. If and to the extent that the obligations of
the Pledgor under this Section 11 are unenforceable for any reason, the Pledgor
hereby agrees to make the maximum contribution to the payment and satisfaction
of such obligations which is permissible under applicable law.

      12.   FURTHER ASSURANCES. The Pledgor agrees that it will join with the
Pledgee in executing and, at its own expense, file and refile under the Uniform
Commercial Code such financing statements, continuation statements and other
documents in such offices as the Pledgee may deem necessary or appropriate and
wherever required or permitted by law in order to perfect and preserve the
Pledgee's security interest in the Collateral and hereby authorizes the Pledgee
to file financing statements and amendments thereto relative to all or any part
of the Collateral without the signature of the Pledgor where permitted by law,
and agrees to do such further acts and things and to execute and deliver to the
Pledgee such additional conveyances, assignments, agreements and instruments as
the Pledgee may reasonably require or deem advisable to carry into effect the
purposes of this Agreement or to further assure and confirm unto the Pledgee its
rights, powers and remedies hereunder.

      13.   THE PLEDGEE AS AGENT. The Pledgee will hold in accordance with this
Agreement and any applicable Control Instructions all items of the Collateral at
any time received under this Agreement or any applicable Control Instructions.
It is expressly understood and agreed that the obligations of the Pledgee as
holder of the Collateral and interests therein and with respect to the
disposition thereof, and otherwise under this Agreement or any applicable
Control Instructions, are only those expressly set forth herein or therein.

      14.   REPRESENTATIONS, WARRANTIES, COVENANTS AND AGREEMENTS OF THE
PLEDGOR. The Pledgor hereby represents and warrants that (a) if it is not a
natural person, it is a corporation, partnership or limited liability company
duly organized and validly existing in good standing under the laws of the state
of its organization; (b) it is the legal and/or beneficial owner of the
Collateral and has good title thereto, subject to no pledge, lien, mortgage,
hypothecation, security interest, charge, option or other encumbrance
whatsoever, except the liens and security interests created or contemplated by
this Agreement and, with respect to any Brokerage Accounts (and any Collateral
deposited therein), any applicable agreements with or liens in favor of any
financial intermediaries holding or maintaining the same; (c) it has the power,
authority and legal right to pledge and grant security interests in the
Collateral pursuant to this Agreement; (d) this Agreement and any Control
Instructions to which it is a party have been duly executed and delivered by the
Pledgor and constitutes the legal, valid and binding obligation of the Pledgor
enforceable against the Pledgor in accordance with their respective terms
(subject to limitations as to enforceability which might result from bankruptcy,
insolvency or other laws affecting creditors' rights generally and general
principles of equity); (e) no consent of any other party and no consent,
license, permit, approval or authorization of, exemption by, notice or report
to, or registration, filing or declaration with, any court or governmental
agency is required to be obtained by the Pledgor in connection with the
execution, delivery or performance of this Agreement or the Control
Instructions; (f) the execution, delivery and performance of this Agreement and
the Control Instructions to which it is a party will not violate any provision
of any applicable law or regulation or of any order, judgment, writ, award or
decree of any court, arbitrator or governmental authority, domestic or foreign,
or of the certificate or articles of incorporation or formation, or the by-laws,
or the operating or partnership agreement (as applicable) of the Pledgor, or of

                                       -5-
<PAGE>

any mortgage, indenture, lease, contract or other agreement, instrument or
undertaking to which the Pledgor is a party or which purports to be binding upon
the Pledgor except as contemplated by this Agreement; and (g) the security
interest in the Collateral hereunder is a valid and perfected first priority
security interest therein securing the Obligations, subject to no prior lien or
encumbrance or to any agreement purporting to grant to any third party a lien or
encumbrance on the property or assets of the Pledgor which would include any of
the Collateral subject to, in the case of any Brokerage Accounts (and any
Collateral deposited therein), any applicable agreements with or liens in favor
of any financial intermediaries holding or maintaining the same. The Pledgor
covenants and agrees that: (i) the Pledgor not sell, assign, transfer, exchange,
or otherwise dispose of, or grant any option with respect to, any of the
Collateral, (ii) the Pledgor shall not create, incur or permit to exist any lien
or option in favor of, or any claim of any person with respect to, any of the
Collateral, or any interest therein, except for the liens provided for or
contemplated by this Agreement whatsoever, except the liens and security
interests created or contemplated by this Agreement and, with respect to any
Brokerage Accounts (and any Collateral deposited therein), any applicable
agreements with or liens in favor of any financial intermediaries holding or
maintaining the same, (iii) the Pledgor will defend the Pledgee's right, title
and security interest in and to the Collateral against the claims and demands of
all persons and entities whomsoever (except as aforesaid); and (iv) the Pledgor
will have like title to and the right to pledge and grant a security interest in
any other property at any time hereafter included in the Collateral hereunder
and will likewise defend the right thereto and security interest therein of the
Pledgee. The Pledgor further covenants and agrees to pay, and to save the
Pledgee, Parent and Subsidiary harmless from, any and all liabilities with
respect to, or resulting from any delay in paying, any and all stamps, excise,
sales or other taxes which may be payable or determined to be payable with
respect to any of the Collateral or in connection with any of the transactions
contemplated by this Agreement.

      15.   PLEDGOR'S OBLIGATIONS ABSOLUTE, ETC. The obligations of the Pledgor
under this Agreement shall be absolute and unconditional and shall remain in
full force and effect without regard to, and shall not be released, suspended,
discharged, terminated or otherwise affected by, any circumstance or occurrence
whatsoever, including, without limitation: (a) any renewal, extension, amendment
or modification of or addition or supplement to or deletion from all or any of
the Notes or Obligations, or any assignment or transfer thereof; (b) any waiver,
consent, extension, indulgence or other action or inaction under or in respect
of all or any of the Notes, Obligations or this Agreement; (c) any furnishing of
any additional security to the Pledgee, Parent, Subsidiary or any of their
respective assignees, or any acceptance thereof, or any release of any security
by the Pledgee, Parent, Subsidiary or any of their respective assignees; (d) any
limitation on any party's liability or obligations under any or all of the
Notes, Obligations, this Agreement or additional security agreement(s), or any
invalidity or unenforceability, in whole or in part, of any of the foregoing; or
(e) any bankruptcy, insolvency, reorganization, composition, adjustment,
dissolution, liquidation or other like proceeding relating to any obligor with
respect to any of the Obligations, or any action taken with respect to this
Agreement by any trustee or receiver, or by any court, in any such proceeding,
whether or not the Pledgor shall have notice or knowledge of any of the
foregoing.

      16.   REGISTRATION, ETC. (a) If an Event of Default shall have occurred
and be continuing and the Pledgor shall have received from the Pledgee a written
request or requests that the Pledgor cause any registration, qualification or
compliance under any Federal or state securities law or laws to be effected with
respect to all or any part of the collateral consisting of equity securities
issued by Parent or MDI (the "Pledged Securities"), the Pledgor as soon as
practicable and at its expense will use its reasonable efforts to cause such
registration to be effected (and be kept effective) and will use its reasonable
efforts to cause such qualification and compliance to be effected (and be kept
effective) as may be so requested and as would permit or facilitate the sale and
distribution of such Pledged Securities, including, without limitation,
registration under the Securities Act of 1933 as then in effect (or any similar
statute then in effect), appropriate qualifications under applicable blue sky or
other state securities laws and appropriate compliance with any other government
requirements, provided, that the Pledgee shall furnish to the Pledgor such
information regarding the Pledgee as the Pledgor may request in writing and as
shall be required in connection with any such registration, qualification or
compliance. The Pledgor will cause the Pledgee to be kept reasonably advised in

                                       -6-
<PAGE>

writing as to the progress of each such registration, qualification or
compliance and as to the completion thereof, will furnish to the Pledgee such
number of prospectuses, offering circulars or other documents incident thereto
as the Pledgee from time to time may reasonably request, and will indemnify the
Pledgee, Parent and Subsidiary and all others participating in the distribution
of such Pledged Securities against all claims, losses, damages and liabilities
caused by any untrue statement (or alleged untrue statement) of a material fact
contained therein (or in any related registration statement, notification or the
like) or by any omission (or alleged omission) to state therein (or in any
related registration statement, notification or the like) a material fact
required to be stated therein or necessary to make the statements therein not
misleading, except insofar as the same may have been caused by an untrue
statement or omission based upon information furnished in writing to the Pledgor
by the Pledgee expressly for use therein.

            (b)   If at any time when the Pledgee shall determine to exercise
its right to sell all or any part of the Pledged Securities pursuant to Section
7, and such Pledged Securities or the part thereof to be sold shall not, for any
reason whatsoever, be effectively registered under the Securities Act of 1933,
as then in effect, the Pledgee may, in its sole and absolute discretion, sell
such Pledged Securities or part thereof by private sale in such manner and under
such circumstances as Pledgee may deem necessary or advisable in order that such
sale may legally be effected without such registration, provided that at least
10 days' notice of the time and place of any such sale shall be given to the
Pledgor. Without limiting the generality of the foregoing, in any such event the
Pledgee, in its sole and absolute discretion (i) may proceed to make such
private sale notwithstanding that a registration statement for the purpose of
registering such Pledged Securities or part thereof shall have been filed under
such Act, (ii) may approach and negotiate with a single possible purchaser to
effect such sale, and (iii) may restrict such sale to a purchaser who will
represent and agree that such purchaser is purchasing for its own account, for
investment, and not with a view to the distribution or sale of such Pledged
Securities or part thereof. In the event of any such sale, the Pledgee shall
incur no responsibility or liability for selling all or any part of the Pledged
Securities at a price which the Pledgee, in its sole and absolute discretion,
may in good faith deem reasonable under the circumstances, notwithstanding the
possibility that a substantially higher price might be realized if the sale were
deferred until after registration as aforesaid.

      17.   THE PLEDGOR'S RELEASE OF PLEDGEE. Under no circumstances shall
Pledgee, Parent or Subsidiary be deemed to assume any responsibility for or
liability, obligation or duty with respect to any part or all of the Pledged
Securities, Brokerage Accounts or other Collateral of any nature or kind or any
matter or proceeding arising out of or related thereto, except as required by
applicable law. Pledgee shall not be required to take any action of any kind to
collect, preserve or protect its or the Pledgor's rights in the Collateral, or
against other persons or entities. The Pledgor hereby releases Pledgee, Parent
and Subsidiary from any claims, causes of action and demands with respect to the
Collateral or any actions taken or omitted to be taken by Pledgee with respect
thereto so long as such actions which relate to the custody and preservation of
the Collateral in Pledgee's possession are taken or omitted to be taken with
reasonable care, and the Pledgor hereby agrees to hold Pledgee harmless from and
with respect to any and all such claims, causes of action and demands.
Nevertheless, Pledgee agrees to exercise reasonable care in the physical
preservation of the Collateral in its actual possession.

      18.   TERMINATION. Upon the payment and performance in full of all of the
Obligations, this Agreement shall terminate, all Control Instructions shall
terminate, and such of the Collateral as have not theretofore been sold or
otherwise applied pursuant to the terms of this Agreement shall be delivered to
the Pledgor or as the Pledgor may direct in writing.

      19.   NOTICES. All notices, requests, demands, directions, consents or
waivers, statements, reports and other communications hereunder shall be deemed
to have been given when mailed by first-class, registered or certified mail
(postage prepaid) or transmitted by telecopier to the applicable party or
parties.

                                       -7-
<PAGE>

      20.   GENERAL. This Agreement shall bind and inure to the benefit of the
respective successors and permitted assigns of the parties hereto. Neither this
Agreement nor the obligations of the Pledgor hereunder may be assigned or
delegated by the Pledgor without the prior written consent of the Pledgee. This
Agreement may not be changed orally, but only by an instrument in writing signed
by the person against whom enforcement of such change, modification or discharge
is sought.

      21.   SEVERABILITY. If any word, phrase, sentence, paragraph, provision or
section of this Agreement shall be held, declared, pronounced or rendered
invalid, void, unenforceable or inoperative for any reason by any court of
competent jurisdiction, governmental authority, statute, or otherwise, such
holding, declaration, pronouncement or rendering shall not adversely affect any
other word, phrase, sentence, paragraph, provision or section of this Agreement,
which shall otherwise remain in full force and effect and be enforced in
accordance with its terms, provided such holding, declaration, pronouncement or
rendering does not release the Pledged Securities or other Collateral from the
pledge or security interest hereunder or result in or permit a prior lien on the
Pledged Securities or other Collateral or adversely affect Pledgee's rights upon
an Event of Default to transfer and vote, and in compliance with law, sell, the
Pledged Securities. Any other holding, declaration, pronouncement or rendering
of any word, phrase, sentence, paragraph, provision or section of this Agreement
as invalid, void, unenforceable or inoperative shall constitute an Event of
Default under section 2 of the Notes.

      22.   GOVERNING LAW. THIS AGREEMENT SHALL BE GOVERNED BY, AND CONSTRUED IN
ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW YORK.

      23.   COUNTERPARTS. This Agreement may be executed in any number of
counterparts, each of which for all purposes shall be deemed to be an original.

      IN WITNESS WHEREOF, the parties hereto have caused this Pledge Agreement
to be executed as of the day and year first above written.

CADMUS CORPORATION                     ELXSI CORPORATION,
as Pledgor                             as Pledgee

By: /s/ ALEXANDER M. MILLEY            By: /s/ DAVID M. DOOLITTLE
    ----------------------------           ---------------------------
    Alexander M. Milley                    David M. Doolittle
    Title: President                       Title: Vice President & Chief
                                                  Financial Officer

                                       -8-
<PAGE>

                                   Schedule 1
                                   ----------

                               Initial Collateral
                               ------------------

1.    Physical Securities
      -------------------

a.    8,400 shares of Molecular Diagnostics, Inc. f/k/a Ampersand Medical
      Corporation ("Ampersand") Series E Preferred Stock represented by
      Certificate No. E0126 registered in the name of Alexander M. Milley (owned
      beneficially by Pledgor).

b.    14,017 shares of common stock of Parent represented by Certificate No. ___
      registered in the name of Pledgor.

2.    Brokerage Accounts
      ------------------

a.    N.B. Zoullas Securities, Inc. Account No. 663-00095, in which there is
      currently deposited 192,488 shares of common stock of Parent; 48,271.44
      shares of Series E Convertible Preferred Stock of Molecular Diagnostics,
      Inc. f/k/a Ampersand Medical Corporation ("Ampersand"); 52,881 shares of
      common stock of Ampersand; and other marketable securities; all subject to
      the lien of certain mortgage loans.

b.    N.B. Zoullas Securities, Inc. Account No. 663-00199, in which there is
      currently deposited 25,000 shares of common stock of Parent; 10,000 shares
      of Ampersand common stock; and cash.
<PAGE>

                                    Exhibit A
                                    ---------

                  Form of Brokerage Account Control Instruction
                  ---------------------------------------------
                                  [Letterhead]

N.B. Zoullas Securities, Inc.
909 3rd Avenue, 29th Floor
New York, NY  10022

                                                                  April __, 2002

                              Account No. xxx-xxxxx
                              ---------------------

Ladies and Gentlemen:

      The undersigned ("Account Holder") has granted to ELXSI Corporation, a
Delaware corporation ("Secured Party"), a security interest in and to the
Account Holder's N.B. Zoullas Securities, Inc. brokerage account numbered
xxx-xxxxx (the "Account"). The purpose of this letter is to help perfect the
Secured Party's security interest in the Account by granting it certain control
over the Account and any securities, cash or other property held therein, as
hereinafter provided.

      You are hereby instructed by the Account Holder that:

1.    You may not authorize or engage in any trading or other activity in or
      with respect to the Account, or any securities, cash or other property
      held therein, unless and to the extent jointly instructed in writing by
      both the Account Holder and the Secured Party. However, from and after
      your receipt of written advice from the Secured Party to the effect that
      an "Event of Default" has occurred and is continuing with respect to the
      Account Holder (a "Default Notice"), the Account Holder shall no longer
      have any authorization with respect to such trading and other activity,
      and shall thereupon accept and act upon only the instructions of the
      Secured Party.

2.    Notwithstanding the foregoing, until such time (if any) as you shall have
      received a Default Notice, the Account Holder shall have full authority to
      give you directions with respect to any voting of any securities held in
      the Account.

3.    From and after your receipt of a Default Notice, the Secured Party shall
      have the full power and authority (to the exclusion of the Account
      Holder), to exercise dominion and control over the Account (subject to the
      applicable Account agreement(s) and restrictions), including (without
      limitation) the right to liquidate the account and/or to transfer the
      entire account position to an existing or new account established in the
      name of the Secured Party.

      The foregoing instructions shall remain effective and in full force and
effect until such time (if any) that the Secured Party (with or without the
Account Holder) shall advise you in writing that the security interest referred
to hereinabove shall have been terminated.

                                       Very truly yours,
                                       Cadmus Corporation

                                       By: /s/ ALEXANDER M. MILLEY
                                           -------------------------------------
                                           Alexander M. Milley
                                           Its President

Acknowledged and accepted
ELXSI Corporation

By: /s/ DAVID M. DOOLITTLE
    --------------------------------------------
    David M. Doolittle
    Its Vice President & Chief Financial Officer

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