Document:

Prepared by R.R. Donnelley Financial -- Amendment to Rights Agreement

 Exhibit 4.1 
  

AMENDMENT TO RIGHTS AGREEMENT 
 BETWEEN TULARIK INC. AND 
 WELLS FARGO BANK MINNESOTA, N.A. 
  
 THIS AMENDMENT TO
RIGHTS AGREEMENT (the “Amendment”) is made this 10th day of November, 2003, by and between TULARIK INC., a Delaware corporation (the
“Company”), and WELLS FARGO BANK MINNESOTA, N.A. (the “Rights Agent”). 
  
 WHEREAS, the Company proposes to issue shares of the Company’s common stock, par value $0.001 per share (the “Common
Stock”), in an underwritten public offering duly registered under the Securities Act of 1933, as amended (the “Securities Act”), pursuant to a prospectus supplement to that certain Registration Statement on Form S-3 (Registration No.
333-67366), originally filed by the Company with the Securities and Exchange Commission (the “SEC”) on August 13, 2001, a preliminary version of which prospectus supplement was filed by the Company with the SEC on November 4, 2003, and a
final version of which prospectus supplement is expected by the Company to be filed with the SEC on November 12, 2003 (the “Offering”); and 
  
 WHEREAS, the Company is willing to permit Amgen Inc. (“Amgen”) to acquire shares of Common Stock in connection with the
Offering (such shares, the “Purchased Shares”); 
  
 WHEREAS, the Company and the Rights Agent are parties to that certain Rights Agreement, dated as of December 11, 2002, as amended by an amendment thereto dated May 21, 2003 (as amended, the “Rights
Agreement”); 
  
 WHEREAS, the Company
desires to amend the Rights Agreement to permit Amgen to acquire the Purchased Shares; and 
  
 WHEREAS, the Board of Directors of the Company has approved this Amendment and authorized its appropriate officers to execute and deliver the same to the Rights Agent. 
  
 NOW, THEREFORE, in accordance with the
procedures for amendment of the Rights Agreement set forth in Section 27 thereof, and in consideration of the foregoing and the mutual agreements herein set forth, the parties hereby agree as follows: 
  
 1. Capitalized terms that are not otherwise defined herein shall have
the meanings ascribed to them in the Rights Agreement. 
  
 2.
The definition of “Excluded Stockholder” set forth in Section 1(h) of the Rights Agreement is restated in its entirety as follows: 
  
 “Excluded Stockholder” shall mean: (i) ZKB Pharma Vision AG (including its Affiliates and Associates); provided,
however, that ZKB Pharma Vision AG (including its Affiliates and Associates) shall not be an Excluded Stockholder if ZKB Pharma Vision AG (including its Affiliates and Associates) becomes the Beneficial Owner of more than 21% of the outstanding
Common Shares without the prior approval of the Board of Directors; and (ii) Amgen Inc. (including its Affiliates and Associates) only 

  

 1. 

 
with respect to any Common Shares that it beneficially owns as a result of acquisitions (A) pursuant to that certain Stock Purchase Agreement by and between
the Company and Amgen Inc. dated as of May 21, 2003 as the same may be amended from time to time (the “Stock Purchase Agreement”), (B) of up to 11,358,238 shares of Common Stock (subject to appropriate adjustment for stock splits, stock
dividends payable in shares of Common Stock or securities convertible into Common Stock, recapitalizations, capital reorganizations, consolidations or mergers) from ZKB Pharma Vision AG (including its Affiliates and Associates) of Common Shares (the
“ZKB Acquisition”) that ZKB Pharma Vision AG (including its Affiliates and Associates) beneficially own as of May 21, 2003, or (C) in connection with the public offering of shares of Common Stock pursuant to a prospectus supplement to that
certain registration statement on Form S-3 (Registration No. 333-67366), originally filed by the Company with the Securities and Exchange Commission (the “SEC”) on August 13, 2001, a preliminary version of which prospectus supplement was
filed by the Company with the SEC on November 4, 2003, and a final version of which prospectus supplement is expected by the Company to be filed with the SEC on November 12, 2003 (the “Offering”). 
  
 3. Section 1(o) of the Rights Agreement is hereby amended by deleting
in its entirety the final sentence thereto and replacing it with the following new sentence: 
  
 Notwithstanding anything in this Agreement to the contrary, no Shares Acquisition Date shall be deemed to have occurred solely as a result
of (i) the approval, execution or delivery of the Stock Purchase Agreement or the ZKB Acquisition or the approval of the purchase of Common Stock by Amgen Inc. in connection with the Offering, (ii) the announcement of the Stock Purchase Agreement,
the ZKB Acquisition or the purchase of Common Stock by Amgen Inc. in connection with the Offering, or (iii) the acceptance for payment and purchase of shares of Common Shares of the Company pursuant to the Stock Purchase Agreement or the ZKB
Acquisition or by Amgen Inc. in connection with the Offering. 
  
 4. Section 3(a) of the Rights Agreement is hereby amended by deleting in its entirety the final sentence thereto and replacing it with the following new sentence: 
  
 Notwithstanding anything in this Agreement to the contrary, no Distribution Date shall be deemed to have
occurred solely as a result of (i) the approval, execution or delivery of the Stock Purchase Agreement or the ZKB Acquisition or the approval of the purchase of Common Stock by Amgen Inc. in connection with the Offering, (ii) the announcement of the
Stock Purchase Agreement, the ZKB Acquisition or the purchase of Common Stock by Amgen Inc. in connection with the Offering, or (iii) the acceptance for payment and purchase of shares of Common Shares of the Company pursuant to the Stock Purchase
Agreement or the ZKB Acquisition or by Amgen Inc. in connection with the Offering. 
  
 5. Section 30 of the Rights Agreement is hereby amended by deleting in its entirety the final sentence thereto and replacing it with the following new sentence: 
  
 Nothing in this Agreement shall be construed to give any
holder of Rights or any other Person any legal or equitable rights, remedies or claims under this Agreement by 

  

 2. 

 
virtue of (i) the approval, execution or delivery of the Stock Purchase Agreement or the ZKB Acquisition or the approval of the purchase of Common Stock by
Amgen Inc. in connection with the Offering, (ii) the announcement of the Stock Purchase Agreement, the ZKB Acquisition or the purchase of Common Stock by Amgen Inc. in connection with the Offering, or (iii) the acceptance for payment and purchase of
shares of Common Shares of the Company pursuant to the Stock Purchase Agreement or the ZKB Acquisition or by Amgen Inc. in connection with the Offering. 
  
 6. The Rights Agreement, as amended by this Amendment, shall remain in full force and effect in accordance with its terms. 
  
 7. All the covenants and provisions of this Amendment by or for the
benefit of the Company or the Rights Agent shall bind and inure to the benefit of their respective successors and assigns hereunder. 
  
 8. If any term, provision, covenant or restriction of this Amendment is held by a court of competent jurisdiction or other authority to be invalid,
void or unenforceable, the remainder of the terms, provisions, covenants and restrictions of this Amendment shall remain in full force and effect and shall in no way be affected, impaired or invalidated. 
  
 9. This Amendment shall be deemed to be a contract made under the laws
of the State of Delaware and for all purposes shall be governed by, and construed in accordance with, the laws of such State applicable to contracts to be made and performed entirely within such State. 
  
 10. This Amendment may be executed in any number of counterparts and
each of such counterparts shall for all purposes be deemed to be an original, and all such counterparts shall together constitute but one and the same instrument. 
  
 11. The Company hereby certifies to the Rights Agent that this Amendment is in compliance with Section 27 of the
Rights Agreement. 
  

 3. 

 IN WITNESS WHEREOF, the parties herein have caused
this Amendment to be duly executed and attested, all as of the date and year first above written. 
  

	
	 TULARIK INC.

		
	By:	 	 /s/ Andrew J. Perlman

	 	 	Name: Andrew J. Perlman
	 	 	Title: Executive Vice President

  

		
	 Attest:
	 	 /s/ William J. Rieflin

	 	 	Name: William J. Rieflin
	 	 	Title: Secretary

  

	
	WELLS FARGO BANK MINNESOTA, N.A.
		
	By:	 	 /s/ John D. Baker

	 	 	Name: John D. Baker
	 	 	Title: Assistant Vice President

  

		
	Attest:	 	 /s/ Corbin B. Connell

	 	 	Name: Corbin B. Connell
	 	 	Title: Assistant Vice President

  

 4.Amendment of Lease

 EXHIBIT 10.58 
  
 AMENDMENT OF LEASE 
  
 AGREEMENT dated as of October 31, 2003 between WESTPORT COMMUNICATIONS, LLC, a Delaware limited liability company, having an office at 277
Park Avenue, New York, New York 10172 (“Landlord”), and FIBERNET EQUAL ACCESS, LLC, a New York limited liability company, having an address at 570 Lexington Avenue, Third Floor, New York, New York 10022 (“Tenant”).

  
 W I T N E S
S E T H: 
  
 WHEREAS,
Landlord and FiberNet Telecom Group, Inc., Tenant’s predecessor, entered into an agreement of lease dated as of April 1, 2001 (the “Original Lease”) (the tenant’s interest in which was assigned to Tenant by assignment dated as of
April 1, 2001) and amended by agreements dated as of January 30, 2002, November 7, 2002 and April 1, 2003 (such latter amendment being referred to as the “April 2003 Amendment”)(the Original Lease, as so amended, being referred to as the
“Existing Lease”), pursuant to which Landlord now leases to Tenant and Tenant now leases from Landlord a portion of the ground floor and a portion of the basement more particularly described in the Existing Lease in the building known as
60 Hudson Street, New York, New York; and 
  
 WHEREAS,
Landlord and Tenant wish to amend the Existing Lease as set forth herein. 
  
 NOW, THEREFORE, in consideration of the foregoing and the mutual covenants hereinafter contained, Landlord and Tenant agree that the Existing Lease is hereby amended as follows: 
  
 1. All terms contained in this Agreement shall, for the purposes hereof,
have the same meanings ascribed to them in the Existing Lease unless otherwise defined herein. As used herein, the term “Lease” shall mean the Existing Lease as amended by this Agreement and as the same may be hereafter amended.

  
 2. The following definitions are substituted for those
contained in the April 2003 Amendment: 
  
 (A) “End
Date” means the last day of the first 12-month period in which either (i) Meet-Me Room Fees plus Transport Fees equal at least $3,000,000.00, or (ii) gross revenues from operations for all FiberNet Entities combined
(“FiberNet Revenues”) equal at least $37,000,000.00. Tenant shall submit to Landlord, within ten (10) business days after written request from Landlord, such financial statements and other data as may be reasonably necessary to monitor
such Meet-Me Room Fees, Transport Fees and FiberNet Revenues (in addition to the records required to be submitted to Landlord under the provisions of the Original Lease); and 
  
 (B) “CEO Event” means the failure by Michael Liss to hold and fulfill the title, responsibilities and authority of
the Chief Executive Officer or Chairman of the Board of Directors of FTG, other than solely by reason of his death or disability. 
  
 3. Tenant agrees to reimburse Landlord, within ten (10) days after demand, for Landlord’s documented out-of-pocket legal fees and disbursements
incurred in connection with the preparation and negotiation of this Agreement. 
  
 4. The covenants, agreements, terms and conditions contained in this Agreement shall bind and inure to the benefit of the parties hereto and their respective successors, and, except as otherwise provided in the Lease,
their respective assigns. 
  
 5. Except as amended by this
Agreement, the Existing Lease and all covenants, 

 
agreements, terms and conditions thereof shall remain in full force and effect and the Existing Lease, as so amended, is hereby in all respects ratified and
confirmed. This Agreement represents the entire understanding and agreement of the parties with respect to the subject matter hereof. 
  
 6. Tenant covenants, represents and warrants that Tenant has had no dealings or communications with any broker or agent in connection with the
consummation of this Agreement other than Williams Real Estate Co. Inc. (the “Broker”) and Tenant covenants and agrees to indemnify Landlord from and against all costs, expenses (including reasonable attorneys’ fees and disbursements)
and liability for any commission or other compensation claimed by any broker or agent (other than the Broker) with respect to this Agreement. Landlord shall pay any commission due to Broker on account of the execution of this Agreement. This
Paragraph shall survive the termination of this Agreement. 
  
 7.
This Agreement may not be changed orally, but only by a writing signed by the party against whom enforcement thereof is sought. 
  
 8. The submission of this Agreement to Tenant shall not constitute an offer by Landlord to execute and exchange this Agreement with Tenant and is made
subject to Landlord’s acceptance, execution and delivery thereof. 
  

 -2- 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the day and year first
above written. 
  

	WESTPORT COMMUNICATIONS, LLC
		
	 By:
	 	  

	 	 	 Name:

	 	 	 Title:

	
	FIBERNET EQUAL ACCESS, LLC
		
	 By:
	 	  

	 	 	 Name:

	 	 	 Title:

  
 By its execution below, the
undersigned acknowledges its consent to this Agreement. 
  

	 HUDSON TELEGRAPH ASSOCIATES, L.P., a
 New York limited partnership, Overlandlord

		
	 By:
	 	 Sixty Hudson Management LLC

			
	 	 	 By:
	 	  

	 	 	 	 	 Name:
                                        ,
Manager

  
 By its execution below, the
undersigned acknowledges its agreement to be bound by this Agreement and the Existing Lease jointly and severally with Tenant. 
  

	FIBERNET TELECOM GROUP, INC.
		
	 By:
	 	  

	 	 	 Name:

	 	 	 Title:

  

 -3-

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