Document:

Exhibit 4.46

ABN 83 010 548 357

TO WHOM IT MAY CONCERN

Ladies and Gentlemen:

Re:      CONCENT

 

The
undersigned hereby consents to the references to (1) the undersigned’s name
included or incorporated by reference in the
Registration Statement on Form F-80 being filed by Uranium One Inc.
under the United States Securities Act of 1933, as amended, in connection with
the report entitled the “Summary of
Feasibility Study, Honeymoon Uranium Project, South Australia” dated July 31,
2006 and (2) all other references to the undersigned included or incorporated
by reference in such Registration Statement.

 

Date: June 25, 2007

	
   

  	
  /s/ Philip D. Bush

  	
   

  
	
   

  	
  Philip D. Bush

  	
   

  

 

 

PO Box 296 Kenmore Q 4069 Australia  Phone 61 7 3374 1647  Fax 61 7 3374 1583  e-mail pdbush@gil.com.auExhibit 4.47

	
  Uranium One Africa Limited

  Postnet Suite 271 · Private Bag
  X30500 · Houghton 2041

  Block A · Empire Park · 55 Empire Rd ·
  Parktown · Gauteng · South Africa

  Tel 27 11 482 3605 · Fax 27 11 482
  3604

  	
  

  

 

CONSENT

Ladies and Gentlemen:

The undersigned hereby
consents to the references to (1) the undersigned’s name included or
incorporated by reference in the Registration Statement on Form F-80 being
filed by Uranium One Inc. (the “Company” ) under the United States Securities
Act of 1933, as amended, in connection with certain scientific and technical
information contained in (a) the Company’s Annual Information Form for the year
ended December 31, 2006, (b) the Company’s news releases attached as exhibits
to the Company’s Material Change Reports dated January 24, 2007 and February
16, 2007, (c) the Company’s Management’s Discussion and Analysis of Financial
Condition and Results of Operation for the year ended December 31, 2006 and (d)
the Company’s investor conference call and transcript thereof, and related
slide show, each dated June 4, 2007 and (3) all other references to the
undersigned included or incorporated by reference in such Registration
Statement.

Date: June 25, 2007

	
  

  	
  /s/ Dr. R.A.
  Stewart

  
	
   

  	
  Dr. R.A. Stewart

  

 

Directors: Thuthukile
Skweyiya (Non-Executive Chairperson) • Neal Froneman • Jean Nortier • Robert
Van Niekerk

• Savannah Maziya* • Sandile Zungu*

*(Non-executive)

Reg No. 1921/006955/06

Company Secretary C
BannermanExhibit 4.48

 

	
  

  	
   

  	
  SRK House

  265 Oxford Road, Illovo

  2196 Johannesburg

  

  PO Box 55291

  
	
   

  	
   

  	
  Northlands

  
	
   

  	
   

  	
  2116 South Africa

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
  e-Mail: johannesburg@srk.co.za

  
	
   

  	
   

  	
  URL: http://www.srk.co.za

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
  Tel: +27 (11) 441 1111

  
	
   

  	
   

  	
  Fax: +27 (11) 880 8086

  

 

June 22nd , 2007

CONSENT

Ladies and
Gentlemen:

The undersigned hereby consents to the references to
(1) the undersigned’s name included or incorporated by reference in the
Registration Statement on Form F-80 being filed by Uranium One Inc. under the
United States Securities Act of 1933, as amended, in connection with (a) the
report entitled the “Dominion Uranium Project, North West Province, Republic of
South Africa” dated August 1, 2006 and amended on October 26, 2006 and (b) the
report entitled the “Dominion Uranium Project Northwest Province, Republic of
South Africa” dated March 2, 2007 and (2) all other references to the
undersigned included or incorporated by reference in such Registration
Statement.

	
  /s/ Roger Dixon

  	
   

  
	
  Roger Dixon

  	
   

  
	
  Partner

  	
   

  

 

	
   

  

  	
   

  	
  Partners  JCJ Boshoff, MJ Braune, JM Brown, JAC
  Cowan, CD Dalgliesh, RJ Dixon, T Hart, PR Labrum, LGA Maclear,
  RRW McNeill, HAC Meintjes, BJ Middleton, MJ Morris, GP Murray, GP
  Nel, VS Reddy, PN Rosewarne, PE Schmidt, PJ Shepherd,
  AA Smithen, VM Simposya, PJ Terbrugge, KM Uderstadt, DJ
  Venter, HG Waldeck, A Wood, A J van der Merwe

  	
   

  	
   

  Cape Town        +27 (0) 21 409 2400

  Durban               +27 (0) 31 312 1355

   

  
	
   

  	
  Directors  AJ Barrett, PR Labrum, BJ Middleton, MJ Morris, PE
  Schmidt, PJ Terbrugge, MB Zungu, S Mayekiso

   

  	
   

  	
   

  East London       +27 (0) 43 748 6292

  
	
   

  	
   

  	
  Associates AN Birtles, SA
  McDonald, DM Duthe, R Gardiner, WA Naismith, JP Odendaal, D Visser,
  AC White, ML Wertz, AC Woodford

  	
   

  	
   

  Harare                 +263
  (4) 496 182

  
	
   

  	
   

  	
   

  	
   

  	
   

  
	
  

  	
   

  	
  Consultants  AC Burger, BSc (Hons);  IS
  Cameron-Clarke, PrSci Nat, MSc;  JH de Beer, PrSci
  Nat, MSc; GA Jones, PrEng,
  PhD;  WD Ortlepp, PrEng, MEng; TR Stacey, PrEng, DSc; OKH Steffen, PrEng, PhD; RJ Stuart, PrTech Eng,  GDE;  DW Warwick, PrSci Nat, BSc (Hons)

  	
   

  	
  Johannesburg      +27 (0) 11 441 1111

   

  Pietermaritzburg +27 (0) 33
  345 6311

  
	
   

  	
   

  	
   

  	
   

  
	
   

  	
  Corporate Shareholder:  Kagiso Enterprises (Pty) Ltd

  	
  

  	
   

  	
  Port Elizabeth     +27 (0) 41 581 1911

   

  Pretoria               +27 (0) 12 361 9821

  
	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
   

  	
   

  	
  SRK Consulting (South Africa) (Pty)
  Ltd

  	
  Reg No 1995.012890.07

  	
   

  	
  Rustenburg         +27 (0) 14 594 1280Exhibit 4.49

 

	
  SCOTT WILSON RPA

  	
  www.scottwilson.com

  
	
   

  	
  www.scottwilsonmining.com

  
	
   

  	
   

  
	
   

  	
  Suite 501

  
	
   

  	
  55 University Avenue

  
	
   

  	
  P.O. Box 55

  
	
   

  	
  Toronto, Ontario M5J 2H7

  
	
   

  	
  Tel: (416) 947-0907

  
	
   

  	
  Fax: (416) 947-0395

  

 

CONSENT

Ladies and Gentlemen:

The undersigned hereby
consents to the references to (1) the undersigned’s name included or
incorporated by reference in the Registration Statement on Form F-80 being
filed by Uranium One Inc. under the United States Securities Act of 1933, as
amended, in connection with (a) the report entitled “Technical Report On The
South Inkai Uranium Project” dated March 20, 2006 and (b) the report entitled
“Technical Report On The North Kharassan Uranium Project, Kazakhstan” dated
October 13, 2005 as revised March 21, 2006 and (c) the report entitled
“Technical Report on the Akdala Mine, Kazakhstan” dated March 21, 2006 and (2)
all other references to the undersigned included or incorporated by reference
in such Registration Statement.

	
  Date:
  June 25, 2007

  
	
   

  
	
   

  	
  /s/ Thomas Pool, P.E.

  	
   

  
	
   

  	
  Thomas Pool, P.E.Exhibit 4.50

 

June 25, 2007

	
  British Columbia Securities Commission 

  	
  File name

  
	
  Alberta Securities Commission

  	
   

  
	
  Saskatchewan Financial Services Commission, 

  	
  Direct tel

  
	
  Securities Division 

  	
   

  
	
  The Manitoba Securities Commission

  	
  Direct fax

  
	
  Ontario Securities Commission 

  	
   

  
	
  Autorité des Marchés Financiers du Québec

  	
  Email

  
	
  New Brunswick Securities Commission

  	
   

  
	
  Nova Scotia Securities Commission

  	
   

  
	
  Registrar of Securities, Prince Edward Island

  	
   

  
	
  Securities Commission of Newfoundland and

  	
   

  
	
  Labrador

  	
   

  
	
  Toronto Stock Exchange

  	
   

  
	
  Uranium One Inc.

  	
   

  
	
  Energy Metals Corporation

  	
   

  

 

Re: Consent

Ladies and Gentlemen:

The undersigned hereby consents to the references to
(1) the undersigned’s name included or incorporated by reference in the
Registration Statement on Form F-80 being filed by Uranium One Inc. under the
United States Securities Act of 1933, as amended, in connection with the report
entitled the “Honeymoon Uranium Project – Summary of Feasibility Study 400 tpa
U308 Equivalent” dated July 31, 2006 and (2) all other references to the
undersigned included or incorporated by reference in such Registration
Statement.

Date: June 25, 2007

	
  

  	
  /s/ V.G. Absolon

  	
   

  
	
   

  	
  STUDY MANAGER

  	
   

  

 

Mayfield
Engineering Pty Limited

ABN 22 112 829 624

43-69 Sturt Street

Adelaide SA 5000

Tel +61 (08) 8238
5000

Fax +61 (08) 8238
5001

E-mail mayfield@mayfieldeng.com.au

www.mayfieldeng.com.au

 1Exhibit 4.51

	
  

  	
  P O Box 262, Dunnottar,
  1590, South Africa

  	
   

  
	
   

  	
  tel 27 11 814 4290  fax 27 11 814 7975

  	
   

  

 

CONSENT

Ladies and Gentlemen:

The undersigned hereby
consents to the references to (1) the undersigned’s name included or incorporated
by reference in the Registration Statement on Form F-80 being filed by Uranium
One Inc. (the “Company”) under the United States Securities Act of 1933, as
amended, in connection with the preparation of certain of the scientific and
technical information contained in the Company’s Annual Information Form for
the year ended December 31, 2006 related to the Modder East Gold Project and
(2) all other references to the undersigned included or incorporated by
reference in such Registration Statement.

	
  Date: June 25, 2007

  	
   

  
	
   

  	
   

  
	
   

  	
   

  
	
   

  	
  /s/ Warwick Bullen

  	
   

  
	
   

  	
  Warwick Bullen

  

 

DIRECTORS: S Zungu
(Non-Executive Chairman), N Froneman (Chief Executive Officer), DJ Nortier
(Chief Financial Officer), R Van Niekerk (Executive), S Swana
(Non-Executive), P Kruger (Executive), S. Maziya (Non-Executive), K Dicks
(Non-Executive) P.Kruger (Company Secretary).

Aflease Gold
Limited  Reg No: 1984/006179/06Exhibit 10.1

FOURTH
MODIFICATION TO CREDIT AGREEMENT AND PROMISSORY NOTE

This
FOURTH MODIFICATION TO CREDIT AGREEMENT AND PROMISSORY NOTE (this “Agreement”)
is made as of the 29th day of June, 2007, by and between BIOSPHERE
MEDICAL, INC., a Delaware corporation (the “Borrower”), and BROWN BROTHERS
HARRIMAN & CO., a New York general partnership with an office at 40 Water
Street, Boston, Massachusetts 02109 (the “Lender”), in the following
circumstances:

A.                                   The
Lender has established a revolving line of credit for the Borrower in the
maximum amount of $3,000,000, (the “Loan”) which Loan is evidenced by the
Promissory Note dated May 17, 2002 made by Borrower in favor of Lender in the
original principal amount of $5,000,000 as thereafter reduced to the principal
amount of $3,000,000 and amended thereafter (the “Note”).

B.                                     The
Loan is governed, in part, by the Credit Agreement dated May 17, 2002 by and
between the Borrower and the Lender, as amended from time to time (the “Credit
Agreement”), and is secured by, among other things, the Security Agreement
dated May 17, 2002 by and between Borrower and Lender (the “Security Agreement”).

C.                                     The
Borrower has requested that the Lender extend the Maturity (as defined in the
Credit Agreement) of the Loan, and the Lender has agreed to the Borrower’s
request, but only upon the terms and conditions set forth herein and in the
documents executed in connection herewith.

NOW, THEREFORE, in consideration of the foregoing and
the mutual covenants herein contained, and for other good and valuable
consideration, the receipt and sufficiency of which are hereby acknowledged,
the parties signatory hereto agree as follows:

1.             Definitions.  Except as otherwise defined in this Fourth
Modification, terms defined in the Credit Agreement are used herein as defined
therein.

“First Amendment”  The First Amendment dated as of March 10th, 2003 by and between the
Borrower and the Lender.

“Loan Documents”
shall mean collectively, this Agreement, the Credit Agreement, the Note, the
Security Agreement, the First Amendment, the Second Modification, the Third
Modification and any and all financing statements, agreements, instruments and
certificates now or hereafter related hereto or thereto or executed in
connection herewith or therewith, all as amended from time to time.

“Second Modification”  The Second Modification dated as of June 30th, 2004 by and between the
Borrower and the Lender.

“Third Modification”  The Third Modification dated as of June 29th, 2005 by and between the
Borrower and the Lender.

2.             Amendments.  Subject to the satisfaction of the conditions
precedent specified in Section 3 below, but effective as of the date hereof,
the Credit Agreement and the Note shall be amended as follows:

(a)           In
order to give effect to the extension of the Maturity,

(i)                                     The
reference to “June 29, 2007” in Section 1.1 of the Credit Agreement is hereby
deleted and the date “June 29, 2009” is substituted therefore and inserted in
place thereof.

(ii)                                  The
reference to “June 29, 2007” in the third line of the first paragraph of the
Note is hereby deleted and the date “June 29, 2009” is substituted therefore
and inserted in place thereof.

(b)           In
order to give effect to increase the limitation on capital lease obligations
secured by liens permitted under Section 6.2(g),

(i)                         The
reference to “$500,000” in Section 6.3(e) of the Credit Agreement is hereby
deleted and the amount of “$1,000,000” is substituted therefore and inserted in
place thereof.

3.             Conditions Precedent.  The amendments to the Credit Agreement and
the Note set forth in Section 2 hereof shall become effective, as of the date
hereof, upon satisfaction of the following conditions precedent:

(a)                                  The
Lender shall have received the following documents, each of which shall be
satisfactory to the Lender in form and substance:

(i)                                     This
Fourth Modification, duly executed by each of the parties hereto.

(ii)                                  A
certificate of an officer of the Borrower certifying as to the Borrower’s
charter and bylaws and the corporate (or equivalent) authority for the Borrower
(including without limitation, board of director resolutions or equivalent
authorization and evidence of the incumbency of officers for the Borrower) with
respect to the execution, delivery and performance of this Agreement, the
Credit Agreement as amended hereby and the other Loan Documents and the 

transactions contemplated
by the Credit Agreement as amended hereby and the other Loan Documents.

(iii)                               A
certificate dated as of the date hereof, signed by the Chief Executive Officer,
Chief Financial Officer or such other executive officer of the Borrower as may
be reasonably acceptable to the Lender, to the effect set forth in Sections
(b), (c) and (d) hereof.

(iv)                              Certificate
of Good Standing from the Secretary of the State of Delaware.

(v)                                 Certificate
of Insurance covering all assets and listing the Lender as loss payee.

(vi)                              Revised
Schedules to the Credit Agreement

(b)                                 The
representations and warranties in Section III of the Credit Agreement hereof
shall be true and correct in all material respects, except as disclosed in the
Revised Schedules referred to in Section 3(a)(vi) hereof (attached hereto as
Exhibits A and B) and except as they relate to a specific prior date.

(c)                                  No
Default or Event of Default under the Credit Agreement shall have occurred and
be continuing on the date hereof, nor shall any Default or Event of Default
result from the consummation of the transactions contemplated herein.

(d)                                 Since
the date of the most recently delivered audited financial statements of the
Borrower, no event or condition shall have occurred or exist which is
reasonably likely to have a material adverse effect on the financial condition
or business of the Borrower.

(e)                                  Concurrently
with the execution and delivery of this Fourth Modification, the Borrower shall
have paid to the Lender an amendment fee in an aggregate amount of $7,500.

4.             Effect
on Loan Documents.  The Credit
Agreement (as amended hereby) and the other Loan Documents (as amended on the
date hereof) shall be and remain in full force and effect in accordance with
their terms and hereby are ratified and confirmed in all respects.  Except as expressly set forth herein or in
any amendment to any other Loan Document executed or delivered on the date
hereof, the execution, delivery, and performance of this Agreement shall not
operate as a waiver or an amendment of any right, power, or remedy of the
Lender under the Credit Agreement or any other Loan Document, as in effect
prior to the date hereof.  The Borrower
hereby ratifies and confirms in all respects all of its obligations and any
prior grant of a security interest 

under the Credit
Agreement (as amended hereby) and the other Loan Documents to which it is a
party.

5.             No Novation; Entire Agreement.  This Agreement evidences solely the amendment
of the terms and provisions of the obligations of the Borrower under the Loan
Documents and is not a novation or discharge thereof.  There are no other understandings, express or
implied, among the Borrower and the Lender regarding the subject matter hereof
or thereof.

6.             Choice
of Law.  The validity of this
Agreement, its construction, interpretation and enforcement, and the rights of
the parties hereunder, shall be determined under, governed by, and construed in
accordance with the laws of The Commonwealth of Massachusetts without regard to
conflicts of laws principles.

7.             Counterparts;
Facsimile Execution.  This Agreement
may be executed in any number of counterparts and by different parties and
separate counterparts, each of which when so executed and delivered shall be deemed
an original, and all of which, when taken together, shall constitute one and
the same instrument.  Delivery of an
executed counterpart of a signature page to this Agreement by facsimile shall
be as effective as delivery of a manually executed counterpart of this
Agreement.  Any party delivering an
executed counterpart of this Agreement by facsimile also shall deliver a
manually executed counterpart of this Agreement but the failure to deliver a
manually executed counterpart shall not affect the validity, enforceability,
and binding effect of this Agreement.

IN WITNESS WHEREOF, the parties hereto have caused
this Fourth Modification to be executed as of the date first above written.

	
  

  	
  BIOSPHERE MEDICAL, INC.,

  
	
   

  	
  as Borrower

  
	
   

  	
   

  	
   

  
	
   

  	
  By:

  	
  /s/ Martin J. Joyce

  
	
   

  	
   

  	
  Name: 

  	
  Martin J. Joyce

  
	
   

  	
   

  	
  Title: 

  	
  Executive Vice President and 

  Chief Financial Officer

  
	
   

  	
   

  
	
   

  	
  BROWN BROTHERS HARRIMAN & CO.,

  
	
   

  	
  as Lender

  
	
   

  	
   

  	
   

  
	
   

  	
  By:

  	
  /s/ Robert D. Hazard

  
	
   

  	
   

  	
  Name: 

  	
  Robert D. Hazard

  
	
   

  	
   

  	
  Title: 

  	
  Vice President

  

 

EXHIBIT A

Schedule
I

Security Interests, Mortgages,
Liens

Capitalized
Leases and Encumbrances

Capitalized Leases

·                  Biosphere
Medical, Inc. (“the Company”) Leases (1) Reactor Cylinder; Electronic Scanning
Equipment; and Packaging Equipment though California First Leasing Corporation.
As of May 31, 2007, the Company had $42,185.13 outstanding on a four year lease
agreement that began in February 2004.

·                  The
Company also leases (1) CISCO Phone System and associated equipment through
CISCO Capital Leasing. As of May 31, 2007, the Company had $30,421.23
outstanding on a five year lease agreement that began in October 2005.

EXHIBIT B

Schedule
II

Litigation,
Investigations and Proceedings

Legal Proceedings 

On August 17, 2005, a lawsuit commenced in the
Circuit Court, Twenty-Second Judicial Circuit, St. Louis, Missouri
captioned Brett Pingel by next friend Dawn LaRose vs.
BioSphere Medical, Inc., Bruce Kirke Bieneman, M.D., St. Louis University
Hospital, John Stith, M.D and St. Louis University. The lawsuit
alleges, among other things, that a patient suffered permanent bilateral
blindness as a result of the use of our Embosphere Microspheres or the
negligence of the health care providers or both factors combined. All
defendants have denied the allegations against them. Plaintiffs seek
compensatory and punitive damages. We carry product liability insurance and
this case is currently being defended by our insurer under reservation of
rights with respect to the claim of punitive damages, for which an exclusion
from coverage exists. We have filed an answer to this lawsuit in which we have
denied the claims being made.

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