Document:

EXHIBIT 10.14
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                     AMPERSAND MEDICAL CORPORATION

                        NOTE PURCHASE AGREEMENT

     This note purchase agreement (this "Agreement") is made as of the
Closing Date (as defined below) by and between Ampersand Medical
Corporation, a Delaware corporation (the "Company"), with its principal
office at 414 North Orleans Street, Suite 305, Chicago, Illinois 60610 and
_________________________________________________ ("Purchaser").

                               RECITALS

     The Company is undertaking the placement and sale (the "Offering") of
up to $1,500,000 principal amount of 6% Convertible Subordinated Notes due
2000, convertible into shares of the Company's common stock, no par value
(the "Common Stock") at a conversion price (the "Conversion Price") as
described in said notes. The notes will be sold by the Company to Purchaser
pursuant to Regulation D under the Securities Act of 1933, as amended (the
"Act") (the "Regulation D Purchasers").

                               AGREEMENT

     In consideration of the mutual promises, representations, warranties
and conditions set forth in the Agreement, the Company and Purchaser agree
as follows:

     1.    PURCHASE AND SALE OF NOTE.

     1.1   Issue of Note.

     (a)   The Company has authorized the issuance and sale to Purchaser,
in reliance upon the Purchaser's representations and warranties contained
in Section 4 and subject to the terms and conditions set forth herein, a 6%
Convertible Subordinated Note in the principal amount of $100,000 (the
"Note"), convertible into up to 500,000 shares of Common Stock (the
"Conversion Shares") pursuant to the exchange of the Note.

     (b)   In reliance upon the representations and warranties of the
Company contained herein, and subject to the terms and conditions set forth
herein, Purchaser agrees to purchase the Note.

     2.    CLOSING DATE; DELIVERY.

     2.1   Closing. The closing of the sale and purchase of the Note under
this Agreement (the "Closing") shall be held at 11:00 am. (Central Standard
Time) on a date mutually agreeable to the Company and Purchaser, but in no
event later than June 4, 1999 (the "Closing Date"), at the offices of the
Company, or at such other place as the Company decides.

     2.2   Delivery. At the Closing, subject to the terms and conditions
hereof, the Company will deliver to Purchaser the Note subscribed for by
Purchaser, dated as of the Closing Date, against payment of the purchase
price therefor by wire transfer, unless other means of payment shall have
been agreed upon by the Purchaser and the Company.

     3.    REPRESENTATIONS AND WARRANTIES OF THE COMPANY.

     Subject to and except as disclosed by the Company in the Confidential
Private Offering Memorandum (the "Offering Memorandum"), the Company
represents and warrants to Purchaser as of the date hereof as follows, and
all such representations and warranties shall be true and correct as of the
Closing Date as if then made and shall survive the Closing:

<PAGE>

     3.1   Organization. The Company is a corporation, duly incorporated,
validly existing and in good standing under the laws of Delaware. The
Company has all requisite power and authority to own or lease its
properties and to conduct its businesses as now conducted. The Company
holds all licenses and permits required for the conduct of its business as
now conducted, which, if not obtained, would have a material adverse effect
on the business, financial condition or results of operations of the
Company taken as a whole. The Company is qualified as foreign or domestic
corporations and is in good standing in all states where the conduct of its
business or its ownership or leasing of property requires such
qualification, except where failure to so qualify would not have a material
adverse effect on the business, financial condition or results of
operations of the Company taken as a whole.

     3.2   Capitalization. As of the date hereof, taking into account the
transaction contemplated hereby, the authorized capital stock of the
Company consists of 50,000,000 shares of Common Stock, 12,000,000 of which
are issued and outstanding, warrants for the purchase of an additional
3,175,850 shares of Common Stock, stock appreciation rights for an
additional 450,000 shares of Common Stock, and subordinated notes
convertible into 4,545,455 shares of Common Stock, (subject to adjustment
in certain circumstances). All of the issued and outstanding shares of
Common Stock have been duly authorized, validly issued and are hilly paid
and non-assessable. Except as stated in the Offering Memorandum and in this
Section 3.2, there are no existing subscriptions, options, warrants, calls,
commitments, agreements, conversion or other rights of any character
(contingent or otherwise) to purchase or otherwise acquire from the Company
at any time, or upon the happening of any stated event, any shares of the
capital stock of the Company, respectively.

     3.3   Authority. The Company has all requisite corporate power and
authority to enter this Agreement and to consummate the transactions
contemplated hereby. The execution and delivery of this Agreement and the
consummation of the transactions contemplated hereby have been duly
authorized by all necessary corporate action on the part of the Company,
and upon its execution and delivery by the Company, such document will
constitute a valid and binding obligation of the Company, enforceable
against the Company in accordance with its terms, and subject as to
enforceability to applicable bankruptcy, insolvency, reorganization,
moratorium and similar laws relating to or affecting creditor's rights from
time to time in effect and subject to general equity principles.

     3.4   Issuance of the Note. The Note, when issued against payment
therefor pursuant to the terms of this Agreement, will be duly and validly
authorized and issued, hilly paid and nonassessable.

     3.5   No Conflict with Law or Documents. The execution, delivery and
consummation of this Agreement and the transactions contemplated hereby
will not: (a) conflict with any provisions of the certificate of
incorporation of the Company, as amended to date, or the bylaws of the
Company, as amended to date; or (b) result in any violation of or default
or loss of a benefit under, or permit the acceleration of any obligation
under (in each case, upon the giving of notice, the passage of time, or
both) any mortgage, indenture, lease, agreement or other instrument,
permit, franchise, license, judgment, order, decree, law, ordinance, rule
or regulation applicable to the Company or its properties.

     3.6   Consents, Approvals and Private Offering. Except for any
filings required under federal and applicable state securities laws, all of
which shall have been made as of the Closing Date to the extent required as
of such time, no consent, approval, order or authorization of, or
registration, declaration or filing with, any federal, state, local or
foreign governmental authority is required to be made or obtained by the
Company in connection with the execution and delivery of this Agreement and
the consummation of the transactions contemplated hereby.

<PAGE>

     3.7   Absence of Certain Developments. Except as described in the
Offering Memorandum, since September 30, 1998, the Company has not: (a)
incurred or become subject to any material liabilities (absolute or
contingent) except current liabilities incurred, and liabilities under
contracts entered into, in the ordinary course of business, consistent with
past practices; (b) mortgaged, pledged or subjected to any lien, charge or
other encumbrance any of its assets, tangible or intangible; (c) sold,
assigned or transferred any of its assets or canceled any debts or
obligations except in the ordinary course of business, consistent with past
practices; (d) suffered any extraordinary losses, or waived any rights of
substantial value; (e) entered into any material transaction other than in
the ordinary course of business, consistent with past practices; or (f)
otherwise had any change in its condition, financial or otherwise, except
as shown on or reflected in the consolidated balance sheet as of March 31,
1999 that is included in the Company's 1999 First Quarter Form 10-Q, except
for changes in the ordinary course of business, consistent with past
practices, none of which individually or in the aggregate has been
materially adverse.

     3.8   Litigation. There are no actions, suits, proceedings or
investigations pending, or to the Company's knowledge, threatened against
or affecting the Company that in the aggregate could reasonably be
anticipated to result in any material adverse effect on the Company.

     3.9   Disclosure. The Offering Memorandum does not contain any untrue
statement of material fact or omit to state a material fact required to be
stated therein or necessary to make the statements therein not misleading.

     3.10  Year 2000 Compliance. The Company has reviewed its products,
business and operations which could be adversely affected by the risk that
computer applications developed, marketed, sold and delivered or used by
the Company may be unable to recognize and properly perform date-sensitive
functions involving dates prior to and after December 31, 1999 (the "Year
2000 Problem"). The Company's products and services provided or delivered
to its customers and the Company's internal information and business
systems will be able to perform properly date-sensitive functions for all
dates before and after January 1, 2000. In addition, the Company has
surveyed those vendors, suppliers and other third parties (collectively,
the "Outside Parties") with which the Company does business and whose
failure to adequately address the Year 2000 Problem could have a material
adverse effect on the business, financial condition or results of
operations of the Company taken as a whole. Based upon the aforementioned
internal review and surveys of the Outside Parties, the Year 2000 Problem
has not resulted in, and is not reasonably expected to have, a material
adverse effect on the business, financial condition or results of
operations of the Company taken as a whole.

     4.    REPRESENTATIONS AND WARRANTIES OF THE PURCHASER.

     Purchaser represents, warrants and covenants with the Company as
follows:

     4.1   Legal Power. Purchaser has the requisite power and authority to
enter into this Agreement, to purchase the Note hereunder, and to carry out
and perform its obligations under the terms of this Agreement.

     4.2   Due Execution. This Agreement has been duly authorized,
executed and delivered by the Purchaser and, upon due execution and
delivery by the Company, this Agreement will be a valid and binding
agreement of the Purchaser.

<PAGE>

     4.3   Investment Representations.

     (a)   Purchaser is acquiring the Note for its own account, not as
nominee or agent, for investment and not with a view to or for resale in
connection with, any distribution or public offering thereof within the
meaning of the Act, except pursuant to an effective registration statement
under the Act.

     (b)   Purchaser understands that: (i) neither the Note nor the
Conversion Shares have been registered under the Act by reason of a
specific exemption therefrom, and may not be transferred or resold except
pursuant to an effective registration statement or exemption from
registration; (ii) each certificate representing the Conversion Shares will
be endorsed with the following legends:

         A)      THE SECURITIES REPRESENTED HEREBY HAVE NOT BEEN
REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), OR
UNDER THE SECURITIES LAWS OF ANY STATE. THESE SECURITIES ARE SUBJECT TO
RESTRICTIONS ON TRANSFERABILITY AND RESALE AND MAY NOT BE TRANSFERRED OR
RESOLD EXCEPT AS PERMITTED UNDER THE ACT AND THE APPLICABLE STATE
SECURITIES LAWS, PURSUANT TO REGISTRATION OR EXEMPTION THEREFROM AND UPON
DELIVERY TO THE ISSUER OF THESE SECURITIES AN OPINION OF COUNSEL IN FORM
AND SUBSTANCE SATISFACTORY TO THE ISSUER TO THE EFFECT THAT ANY PROPOSED
TRANSFER OR RESALE IS IN COMPLIANCE WITH THE ACT AND ANY APPLICABLE STATE
SECURITIES LAWS; and

           B)    Any legend required to be placed thereon by applicable
federal or state securities laws;

and (iii) the Company will instruct any transfer agent not to register the
transfer of any of the Conversion Shares unless the conditions specified in
the foregoing legends are satisfied.

     (c)   Purchaser has received and reviewed the Offering Memorandum. In
addition, Purchaser has been furnished with such materials and has been
given access to such information relating to the Company as it or its
qualified representative has requested and has been afforded the
opportunity to ask questions regarding the Company and the Note, all as
Purchaser has found necessary to make an informed investment decision.

     (d)   Purchaser is an "accredited investor" as such term is defined
in Rule 501 of Regulation D under the Act and was not formed for the
specific purpose of acquiring the Note.

     (e)   Purchaser is not a resident of Canada or any territory thereof.

     5.    COVENANTS OF THE COMPANY.

     5.1   Information. The Company shall deliver to the Purchaser all
annual, quarterly or other reports furnished to the public security
holders; provided that if the Company is not subject to the requirements of
Section 13 or 15(d) of the Securities Exchange Act of 1934, as amended (the
"Exchange Act"), the Company will promptly furnish to the Purchaser: (i) as
soon as available, and in any event within 90 days after the end of each
fiscal year of the Company, a consolidated balance sheet of the Company and
its consolidated subsidiaries, if any, as of the end of such fiscal year
and the related consolidated statements of income, stockholders' equity and
cash flows for such fiscal year, setting forth in each case in comparative
form the figures for the previous fiscal year, all prepared in accordance
with generally accepted accounting principles and reported on by
independent certified public accountants of recognized national standing;
and (ii) as soon as available, and in any event within 45 days after the
end of each of the first three fiscal quarters of each fiscal year of the

<PAGE>

Company, a consolidated balance sheet of the Company and its consolidated
subsidiaries, if any, as of the end of such quarter and the related
consolidated statements of income and stockholders' equity (together with
any other quarterly financial statements being prepared by the Company at
such time), setting forth in each case in comparative form the figures for
the corresponding quarter and the corresponding portion of the Company's
previous fiscal year, all certified (subject to normal year-end
adjustments) as to fairness of presentation and consistency by the chief
financial officer or the chief accounting officer of the Company.

     5.2   Conducting the Offering. The Company will conduct the Offering
under Regulation D of the Act, and the Company represents as follows:

     (a)   Sales to Accredited Investors. The Company will only make
offers and sales of notes through the Offering to Regulation D Purchasers
or potential Regulation D Purchasers it reasonably believes to be
"accredited investors" as that term is defined in Rule 501(a) of Regulation
D under the Act;

     (b)   Regulation D Compliance. Offers and sales of notes through the
Offering will be made in compliance with Regulation D, and the Company has
not and shall not offer to sell notes through the Offering by any form of
general solicitation or general advertising that is prohibited by Rule
502(c) of Regulation D under the Act.

     (c)   Compliance Generally. The Company has and will observe all
securities laws and regulations applicable to it in any jurisdiction in
which it has or may offer, sell or deliver notes through the Offering and
it will not, directly or indirectly, offer, sell or deliver notes through
the Offering or distribute or publish any prospectus, circular,
advertisement or other offering material in relation to notes through the
Offering in or from any state in the United States or country or
jurisdiction except under circumstances that will result in compliance with
any applicable laws and regulations.

     (d)   Blue Sky Compliance. The Company will comply with the state
securities or blue sky laws of each state in which notes are offered
through the Offering.

     5.3   Additional Covenants.

     (a)   The Company shall timely file all such documents required to be
filed by it pursuant to the Exchange Act in order to permit sales under
Rule 144 of the Act.

     (b)   During any period in which the Company is not subject to
Section 13 or 15(d) of the Exchange Act, the Company shall make available
information required to be provided by Rule 144(d)(4), upon request.

     (c)   Upon the request of the Purchaser and the certification of the
Purchaser that it qualifies under Rule 144(k) of the Act, the Company
shall, without further requirement, remove all restrictive legends from the
Purchaser's securities, insofar as such restrictions relate to the transfer
of such securities under the Act.

<PAGE>

     6.    CONDITIONS TO CLOSING.

     6.1   Conditions to Obligations of the Purchaser. The Purchaser's
obligation to purchase the Note at the Closing is subject to the
fulfillment, at or prior to such Closing, of all of the following
conditions:

     (a)   Representations and Warranties True; Performance of
Obligations. The representations and warranties made by the Company in
Section 3 shall be true and correct in all material respects on the Closing
Date with the same force and effect as if they had been made on and as of
said date; except as described in or contemplated by the Offering
Memorandum, the business, assets, financial condition and results of
operations of the Company shall not have been adversely affected in any
material way prior to the Closing Date; and the Company shall have
performed all obligations and conditions herein required to be performed by
it on or prior to the Closing Date.

     (b)   Proceedings and Documents. All corporate and other proceedings
in connection with the transactions contemplated at the Closing hereby and
all documents and instruments incident to such transactions shall be
reasonably satisfactory in substance and form to the Purchaser.

     (c)   Qualifications, Legal Investment. All authorizations, approvals
or permits, if any, of any governmental authority or regulatory body of the
United States or of any state that are required in connection with the
lawful sale and issuance of the Note pursuant to this Agreement shall have
been duly obtained and shall be effective on and as of the Closing Date. No
stop order or other order enjoining the sale of the Note shall have been
issued and no proceedings for such purpose shall be pending or, to the
knowledge of the Company, threatened by the SEC, or any commissioner of
corporations or similar officer of any state having jurisdiction over this
transaction. At the time of the Closing, the sale and issuance of the Note
shall be legally permitted by all laws and regulations to which the
Purchaser and the Company are subject.

     6.2   Conditions to Obligations of the Company. The Company's
obligation to issue and sell the Note at the Closing is subject to the
fulfillment to the Company's satisfaction, on or prior to the Closing, of
the following conditions:

     (a)   Representations and Warranties True. The representations and
warranties made by the Purchaser in Section 4 shall be true and correct at
the Closing Date with the same force and effect as if they had been made on
and as of the Closing Date.

     (b)   Performance of Obligations. Purchaser shall have performed and
complied with all agreements and conditions required to be performed or
complied with by it on or before the Closing Date, and Purchaser shall have
delivered payment to the Company in respect of its purchase of Note.

     (c)   Qualifications, Legal Investment. All authorizations, approvals
or permits, if any, of any governmental authority or regulatory body of the
United States or of any state that are required in connection with the
lawful sale and issuance of the Note pursuant to this Agreement shall have
been duly obtained and shall be effective on and as of the Closing Date. No
stop order or other order enjoining the sale of the Note shall have been
issued and no proceedings for such purpose shall be pending or threatened
by the SEC or any commissioner of corporations or similar officer of any
state having jurisdiction over this transaction. At the time of the
Closing, the sale and issuance of the Note shall be legally permitted by
all laws and regulations to which Purchaser and the Company are subject.

<PAGE>

     7.    MISCELLANEOUS.

     7.1   Governing Law. This Agreement shall be governed by and
construed under the laws of the State of Illinois as applied to agreements
among Illinois residents, made and to be performed entirely within the
State of Illinois without regard to principles of conflict of laws.

     7.2   Indemnification. The Company agrees to indemnify the Purchaser
and each officer, director, employee, agent, partner, stockholder and
affiliate of the Purchaser (collectively, the "Indemnified Parties") for,
and hold each Indemnified Party harmless from and against: (1) any and all
damages, losses, claims and other liabilities of any and every kind,
including, without limitation, judgments and costs of settlement, and (ii)
any and all out-of-pocket costs and expenses of any and every kind,
including, without limitation, reasonable fees and disbursements of counsel
for such Indemnified Parties (all of which expenses periodically shall be
reimbursed as incurred), in each case, arising out of or suffered or
incurred in connection with any of the following: (a) any misrepresentation
or any breach of any warranty made by the Company herein or in the Note,
(b) any breach or non-fulfillment of any covenant or agreement made by the
Company herein or in the Note, and (c) any claim relating to or arising out
of a violation of applicable federal or state securities laws by the
Company in connection with the sale of the Note by the Company.

     7.3   Survival. All representations, warranties, covenants and
agreements contained in or made pursuant to this Agreement or contained in
any certificate delivered pursuant to this Agreement, shall remain
operative and in full force and effect, regardless of any investigation
made by or on behalf of any party hereto, and shall survive the transfer
and payment for the Note and the consummation of the transactions
contemplated hereby.

     7.4   Successors and Assigns. Except as otherwise expressly provided,
the provisions hereof shall inure to the benefit of, and be binding upon,
the successors, assigns, heirs, executors and administrators of the
parties.

     7.5   Entire Agreement. This Agreement and the other documents
delivered pursuant hereto constitute the full and entire understanding and
agreement among the parties with regard to the subjects hereof and no party
shall be liable or bound to any other party in any manner by any
representations, warranties, covenants or agreements except as specifically
set forth herein. Nothing in this Agreement, express or implied, is
intended to confer upon any party, other than the parties and their
respective successors and assigns, any rights, remedies, obligations or
liabilities under or by reason of this Agreement, except as expressly
provided.

     7.6   Separability. In case any provision of this Agreement shall be
invalid, illegal or unenforceable, it shall to the extent practicable, be
modified so as to make it valid, legal and enforceable and to retain as
nearly as practicable the intent of the parties, and the validity, legality
and enforceability of the remaining provisions shall not in any way be
affected or impaired thereby.

     7.7   Amendment and Waiver. Except as otherwise provided, any term of
this Agreement may be amended, and the observance of any term of this
Agreement may be waived (either generally or in a particular instance,
either retroactively or prospectively, and either for a specified period of
time or indefinitely), with the written consent of the Company and
Purchaser. Any amendment or waiver effected in accordance with this section
shall be binding upon each future holder of any security purchased under
this Agreement (including securities into which such securities have been
converted) and the Company.

<PAGE>

     7.8   Notices. All required or permitted notices and other
communications shall be in writing and shall be deemed effectively given
upon personal delivery, on the first business day following mailing by
overnight courier, or on the fifth day following mailing by registered or
certified mail, return receipt requested, postage prepaid, addressed to the
Company and Purchaser at the respective addresses included herein.

     7.9   Fees and Expenses. The Company shall pay its own expenses and
legal fees incurred on its behalf with respect to this Agreement and the
transactions contemplated hereby and shall pay the reasonable and
documented legal fees and expenses of the Purchaser incurred on its behalf
with respect to this Agreement and the transactions contemplated hereby.

     7.10  Titles and Subtitles. The titles of the paragraphs and
subparagraphs of this Agreement are for convenience of reference only and
are not to be considered in construing this Agreement.

     7.11  Counterparts. This Agreement may be executed in any number of
counterparts, each of which shall be deemed an original, but all of which
together shall constitute one instrument.

<PAGE>

          IN WITNESS WHEREOF, the parties have executed this Agreement on
the date first written above.

                      AMPERSAND MEDICAL CORPORATION

                      By:   _______________________________

                      Its:  _______________________________

ATTEST:

By:  _______________________________

Its: _______________________________

                      PURCHASER:

                      By:   ________________________________

                      Its:  ________________________________EXHIBIT 10.15
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THE SECURITIES REPRESENTED HEREBY HAVE NOT BEEN REGISTERED UNDER THE
SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), OR UNDER THE SECURITIES
LAWS OF ANY STATE. THESE SECURITIES ARE SUBJECT TO RESTRICTIONS ON
TRANSFERABILITY AND RESALE AND MAY NOT BE TRANSFERRED OR RESOLD EXCEPT AS
PERMITTED UNDER THE ACT AND THE APPLICABLE STATE SECURITIES LAWS, PURSUANT
TO REGISTRATION OR EXEMPTION THEREFROM. THE ISSUER OF THESE SECURITIES MAY
REQUIRE AN OPINION OF COUNSEL IN FORM AND SUBSTANCE SATISFACTORY TO THE
ISSUER TO THE EFFECT THAT ANY PROPOSED TRANSFER OR RESALE IS IN COMPLIANCE
WITH THE ACT AND ANY APPLICABLE STATE SECURITIES LAWS.

                     AMPERSAND MEDICAL CORPORATION

               6% CONVERTIBLE SUBORDINATED NOTE DUE 2000

$100,000

June 4, 1999

     1.    Principal and Interest. AMPERSAND MEDICAL CORPORATION, a
corporation duly organized and existing under the laws of the State Of
Delaware (the "Company", which term includes any successor), for value
received, hereby promises to pay to the order of ____________________, or
any successor in interest registered on the books of the Company (the
"Holder") in lawful money of the United States at the address of the Holder
set forth below, the principal sum of One Hundred Thousand and 00/100
Dollars ($100,000) on January 28, 2000 (the "Maturity Date") which date may
be extended by the Company to June 30, 2000 (the "Extended Maturity Date"),
together with simple interest from the date hereof, computed on the basis
of a 360-day year of twelve 30-day months in arrears from the date of
original issuance hereof until the Maturity Date or the Extended Maturity
Date to Holders of record of the Notes at the rate set forth in the
following paragraph until the principal hereof is paid or made available
for payment.

     The interest rate on this Note will be 6% per annum from the date of
original issuance. On the Maturity Date or the Extended Maturity Date, the
Company will pay, in lieu of the payment in whole or in part of interest in
cash on this Note, pay interest on this Note through the issuance of
additional shares of Common Stock of the Company at a conversion price as
defined in subsection 2(a) below in an aggregate principal amount equal to
the amount of interest that would be payable with respect to this Note, if
such interest were paid in cash.

     This Note is one of a series of Notes that the Company contemplates
issuing to holders pursuant to a plan to raise no more than One Million
Five Hundred Thousand and 00/1 00 ($1,500,000.00) of proceeds currently
being undertaken by the Company, convertible into Common Stock at a
Conversion Price defined in subsection 2(a) below (the "$1,500,000 Debt
Offering).

           2.    Conversion.

     (a)   Conversion Price. Subject to and upon compliance with the
provisions of this Section 2, the principal amount of this Note (or any
portion hereof that is a multiple of $1,000 or a whole multiple thereof)
shall be convertible into shares of the Company's common stock, no par
value per share (the "Common Stock") at the conversion price (the
"Conversion Price") per each share of Common Stock that is the lesser of
(i) $0.33; (ii) 40% of the lowest conversion price established by the
Company in the contemplated offering by its subsidiary, Ampersand Medical
Corporation ("Ampersand") of $17,000,000 of 6% Convertible Subordinated
Notes due 1999 (the "1999 Debt Offering"); (iii) 40% of the lowest
conversion price below $0.75 in any other offering of debt securities of
the Company in substitution for the 1999 Debt Offering; or (iv) 40% of the
lowest price below $0.75 in any offering of equity securities of the
Company in substitution for the 1999 Debt Offering; provided, however, that
(x) under no circumstances shall the Conversion Price be less than $0.20
per share, (y) provisions (iii) and (iv) of this subsection shall not apply
to the $1,500,000 Debt Offering, and (z) all prices contemplated by (i)
through (iv) and (x) of this subsection shall be appropriately adjusted for
any combination, consolidation stock split or other recapitalization of the
Company.

     (b)   Automatic Conversion. This Note shall be automatically
converted by the Company into shares of Common Stock at the Conversion
Price immediately upon the satisfaction of the following condition: (i) the
Company's receipt of at least Five Million and 00/100 Dollars ($5,000,000)
as part of the 1999 Debt Offering or any other offering of debt or equity
securities of the Company, such minimum amount not to include the
$1,500,000 Debt Offering.

     (c)   Optional Conversion. The Holder may, upon notice to the
Company, convert this Note into shares of Common Stock at the Conversion
Price at any time.

     (d)   Mechanics of Conversion. No conversion notice shall be
necessary in the event of an automatic conversion pursuant to Section 2(b).
In the case of an automatic conversion pursuant to Section 2(b), such
conversion shall be deemed to have been made immediately following the
later to occur of (i) the receipt by the Company of a minimum amount of
$5,000,000 in accordance with Section 2(b) above, and the person or persons
entitled to receive the shares of Common Stock issuable upon such
conversion shall be treated for all purposes as the record holders of such
shares of Common Stock on such date.

     (d)   Reclassification, etc. If the Company at any time shall, by
subdivision, combination or reclassification of securities or otherwise,
change any of the securities into which this Note is convertible into the
same or a different number of securities of any class or classes, the
shares of Common Stock or other securities into which this Note is
convertible shall thereafter be convertible into the kind and number of
shares of stock or other securities or property of the Company or otherwise
to which the Holder would have been entitled if immediately prior to such
change the Holder had acquired the shares of Common Stock or other
securities into which this Note is convertible. If shares of the Company's
Common Stock or other securities purchasable hereunder are subdivided or
combined into a greater or smaller number of shares, the Conversion Price
under this Note shall be proportionately reduced in case of subdivision of
shares or proportionately increased in the case of combination of shares.
No adjustment on account of cash dividends or interest on the Company's
Common Stock or other securities into which this Note is convertible will
be made to the Conversion Price under this Note.

     (e)   Notice of Adjustment. Upon any adjustment of the securities
issuable upon conversion of this Note, the Conversion Price for the shares,
and/or any increase or decrease in the number of shares into which this
Note is convertible upon conversion of this Note, the Company shall give
written notice thereof, by first class mail, postage prepaid, addressed to
the Holder at the address of the Holder as shown on the books of the
Company.

     (f)   Fractional Shares. The Company shall not be required to issue
fractions of shares of Common Stock upon conversion of this Note. In lieu
of any fractional shares to which the Holder of this Note would otherwise
be entitled, the Company shall pay cash equal to such fraction multiplied
by the fair market value of the Common Stock as determined by the Board of
Directors of the Company, whose determination shall be conclusive.

     (g)   No Rights as Stockholder. This Note does not entitle the Holder
to any voting rights or other rights as a stockholder of the Company prior
to the conversion hereof.

     3.    Subordination.

     (a)   "Senior Indebtedness" means the principal of and premium, if
any, and interest on indebtedness of the Company for money borrowed from
commercial banks, equipment lessors, government instrumentalities or other
financial institutions under a secured or unsecured line of credit, term
loan or equipment lease.

     (b)   The Company agrees and the Holder, by acceptance of this Note,
agrees, expressly for the benefit of the present and future holders of
Senior Indebtedness, that, except as otherwise provided herein, upon: (1)
an event of default under any Senior Indebtedness; or (ii) any dissolution,
winding up or liquidation of the Company, whether or not in bankruptcy,
insolvency or receivership proceedings, the Company shall not pay, and the
Holder of this Note shall not be entitled to receive, any amount in respect
of the principal and interest of this Note unless and until the Senior
Indebtedness shall have been paid or otherwise discharged. Upon:
(1) an event of default under any Senior Indebtedness; or (2) any
dissolution, winding up or liquidation of the Company, any payment or
distribution of assets of the Company, which the Holder of this Note would
be entitled to receive but for the provisions hereof, shall be paid by the
liquidating trustee or agent or other person making such payment or
distribution directly to the holders of Senior Indebtedness ratably
according to the aggregate amounts remaining unpaid on Senior Indebtedness
after giving effect to any concurrent payment or distribution to the
holders of Senior Indebtedness. Subject to the payment in full of the
Senior Indebtedness and until this Note is paid in full, the Holder of this
Note shall be subrogated to the rights of the holders of the Senior
Indebtedness (to the extent of payments or distributions previously made to
the holders of Senior Indebtedness pursuant to this paragraph 3(b) to
receive payments or distributions of assets of the Company applicable to
the Senior Indebtedness).

     (c)   This Section 3 is not intended to impair, as between the
Company, its creditors (other than the holders of Senior Indebtedness) and
the Holder of this Note, the unconditional and absolute obligation of the
Company to pay the principal of and interest on this Note or to affect the
relative rights of the Holder of this Note and the other creditors of the
Company, other than the holders of Senior Indebtedness. Nothing in this
Note shall prevent the Holder of this Note from exercising all remedies
otherwise permitted by applicable law upon default under this Note, subject
to the rights, if any, of the holders of Senior indebtedness in respect to
cash, property or securities of the Company received upon the exercise of
any such remedy.

     4.    Redemption. This Note may not be redeemed prior to the Maturity
Date. Should the Company elect to extend the term of this Note, the Note
may not be redeemed prior to the Extended Maturity Date.

     5.    Place of Payment. All payments due to the Holder hereunder
shall be paid to the Holder at the address that the Holder shall have given
written notice to the Company.

     6.    Events of Default and Remedies. If any of the following events
of default (individually, an "Event of Default") shall occur for any reason
whatsoever (and whether it shall be voluntary or involuntary or occur or be
affected by operation of law or otherwise):

     (a)   The Company fails to make payment when due of any principal or
interest payable under this Note, and such failure continues for a period
of ten days after written notice that such payment is due and unpaid;

     (b)   The Company defaults in the observance or performance of any
material agreement or condition under this Note or the Note Purchase
Agreement dated of even date herewith, between the Company and Purchaser
(the "Note Purchase Agreement"), and such default continues for a period of
30 days after written notice of such default is given to the Company by the
Holder;

     (c)   Any representation or warranty made by the Company in the Note
Purchase Agreement shall prove to have been false in any material respect
in the date when made;

     (d)   The Company shall default under any material agreement for
borrowed money that causes the other party thereto to accelerate such
obligation;

     (e)   The Company shall: (i) file, or consent by answer or otherwise
to the filing against it of a petition for relief or reorganization or
arrangement or any other petition in bankruptcy or insolvency law of any
jurisdiction; (ii) make an assignment for the benefit of its creditors;
(iii) consent to the appointment of a custodian, receiver, trustee or other
officer with similar powers of itself or of any substantial part of its
property; (iv) be adjudicated insolvent or be liquidated; or (v) take
appropriate action for the purpose of any of the foregoing; or

     (f)   A court or governmental authority of competent jurisdiction
shall enter an order appointing a custodian, receiver, trustee or other
officer with similar powers with respect to the Company or any substantial
amount of its properties, or if an order for relief with respect to the
Company shall be entered in any case or proceeding for liquidation or
reorganization or otherwise to take advantage of any bankruptcy or
insolvency law of any jurisdiction, or ordering the dissolution, winding up
or liquidation of the Company, or if any petition for any such relief shall
be filed against the Company, and such order or petition shall not be
dismissed or stayed within 60 days after the date of such filing, then
automatically upon the occurrence of such Event of Default the entire
unpaid principal amount of, and the unpaid accrued interest on, this Note
shall become immediately due and payable.

     7.    Additional Remedies. If any Event of Default hereunder shall
have occurred, the Holder may proceed to protect and enforce its rights
under this Note by exercising such remedies as are available to it in
respect thereof under the terms of this Note or applicable law, either by
suit in equity or by action at law, or both, whether for specific
performance of any agreement contained in this Note or in aid of the
exercise of any power granted in this Note. No remedy is intended to be
exclusive and each such remedy shall be cumulative.

     8.    Transfer.

     (a)   The transfer of this Note is registrable by the Holder hereof
in person or by his attorney duly authorized in writing on the books of the
Company. Upon surrender and cancellation of this Note upon any such
transfer, a new Note for the same aggregate principal amount will be issued
to the transferee in exchange herefor.

     (b)   The Company and any transfer or conversion agent may deem and
treat the person in whose name this Note shall be registered upon the books
of the Company as the absolute owner of this Note (whether or not his Note
shall be overdue and notwithstanding any notation of ownership or other
writing hereon) for all other purposes, and neither the Company nor any
transfer or conversion agent shall be affected by any notice to the
contrary. All such payments shall be valid and effectual to satisfy and
discharge the liability on this Note to the extent of the sum or sums so
paid.

     9.    Registration Rights. The Company shall register all of the
shares of Common Stock held by Holder and all of the shares of Common Stock
received pursuant to the conversion of this Note by filing a registration
statement on Form S-3 (or any successor form thereto or any other forms
then available to the Company for registration of securities), and cause
such registration statement to be declared effective on or prior to the
twelve-month anniversary date of the issuance of this Note. The Company
shall cause such registration statement to remain effective for five years
following the initial registration. If the Company fails to fails to
register Holder's Common Stock pursuant to this Section 9, the Company
shall pay to Holder liquidated damages in an amount equal to five percent
(5%) per month (or any part thereof), compounded monthly, on the amount of
the face value of this Note, until such time as the Company is no longer in
breach of this Section 9. Any payments due to Holder pursuant to this
Section 9 shall be made no later than the fifteenth day of the month
following the month in which such liquidated damages were incurred.

     10.   Attorney Fees.

     (a) If the indebtedness represented by this Note or any part thereof
is collected in bankruptcy, receivership or other judicial proceedings or
if this Note is placed in the hands of attorneys for collection after
default, the Company agrees to pay, in addition to the principal and
interest payable hereunder, reasonable attorneys' fees and costs incurred
by the Holder.

     11.   Notices, All notices, reports and other communications required
or permitted hereunder shall be in writing and may be delivered in person,
by telecopy with written confirmation, overnight delivery service or U.S.
mail, in which event it may be mailed by first-class, certified or
registered, postage prepaid, addressed to the Holder at its address as
shown on the books of the Company or to the Company at 414 North Orleans
Street, Suite 305, Chicago, Illinois 60610, Attention: Chief Executive
Officer.

     Each such notice, report or other communication shall for all
purposes under this Note be treated as effective or having been given when
delivered if delivered personally or, if sent by mail, at the earlier of
its receipt or five days after the same has been deposited in a regularly
maintained receptacle for the deposit of the United States mail, addressed
and mailed as aforesaid or, if sent by telecopier with written
confirmation, at the earlier of: (i) 24 hours after confirmation of
transmission by the sending telecopier machine; or (ii) delivery of written
confirmation.

     12.   Amendments. Consents and Waivers. This Note may be amended at
any time and from time to time to add to, eliminate or modify the terms and
provisions hereof and the rights of the Holder hereunder with the written
consent of the Company and the Holder; provided, however, that no such
change shall terminate or impair the subordination provisions of this Note
without the prior written consent of the holders of Senior Indebtedness.
Any amendment, waiver or consent by the Holder of this Note shall be
conclusive and binding upon such Holder and any future Holder of this Note
and of any Note issued in exchange or substitution herefor, irrespective of
whether or not any notation of such amendment, waiver or consent is made
upon this Note or such exchanged or substituted Note. The Company hereby
waives presentment, demand for performance, notice of non-performance,
protest, notice of protest and notice of dishonor. No delay on the part of
the Holder in exercising any right hereunder shall operate as a waiver of
such right or any other right.

     13.   No Recourse. No recourse shall be had for the payment of the
principal or interest on this Note, or any claim based hereon, or otherwise
in respect hereof, this Note, against any incorporator, stockholder,
officer or director, as such, past, present or future, of the Company or
any successor Company, whether by virtue of any constitution, statute or
rule of law, or by the enforcement of any assessment or penalty or
otherwise, all such liability being, by the acceptance hereof and as part
of the consideration for the issue hereof, expressly waived and released.

     14.   Payment Due on Holidays. If the principal of or interest on
this Note falls due on a Saturday, Sunday or legal holiday at the place of
payment, such payment shall be made on the next succeeding business day and
such extended time shall be included in computing interest.

     15.   Severability. If any provision of this Note shall be held
invalid under any applicable laws, such invalidity shall not affect any
other provision of this Note that can be given effect without the invalid
provision and, to this end, the provisions hereof are severable.

     16.   Governing Law. This Note is being delivered in and shall be
construed in accordance with the laws of the State of Illinois, without
regard to the conflicts of laws provisions thereof.

     IN WITNESS WHEREOF, and intending to be legally bound hereby, the
Company has caused this Note to be executed and delivered by its proper and
duly authorized officers as of the date first above written.

                      AMPERSAND MEDICAL CORPORATION

                      BY:    _________________________________

                      NAME:  Peter P. Gombrich
                      TITLE: Chief Executive Officer

Attest:

BY:_______________________________

NAME: Leonard Prange

TITLE: President

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