Document:

EX-10.1

 Exhibit 10.1 

AMENDMENT NO. 2 
 TO

 EMPLOYMENT AGREEMENT 

THIS AMENDMENT NO. 2 TO EMPLOYMENT AGREEMENT (this “Amendment”) is made as of January 31, 2021 (the “Amendment
Effective Date”), by and between Joseph Gardner (the “Executive”) and Aerpio Pharmaceuticals, Inc., a Delaware corporation (the “Company”, and together with the Executive, each, a “Party”,
and collectively, the “Parties”). Capitalized terms used and not otherwise defined herein shall have the meanings ascribed to such terms in the Employment Agreement (as defined below). 

WHEREAS, the Parties entered into an Employment Agreement dated March 15, 2017 (the “March 2017 Agreement”), which
replaced a prior executive employment agreement between the Parties, dated September 16, 2013 (the “Prior Employment Agreement”) except that the provisions of Section 6 of the Prior Employment Agreement (the
“Restrictive Covenants”) were not replaced but, rather, were specifically preserved and reaffirmed as material terms of the March 2017 Agreement; 

WHEREAS, the Parties entered into Amendment No. 1 to Employment Agreement dated October 8, 2017 (together with the March 2017
Agreement, the “Employment Agreement”); and 
 WHEREAS, the Executive and the Company desire to amend certain provisions of
the Employment Agreement as set forth herein. 
 NOW, THEREFORE, in consideration of the foregoing and for other good and valuable
consideration, the receipt and sufficiency of which are hereby acknowledged, the Executive and the Company hereby agree as follows: 
 1.
Section 4(b) of the Employment Agreement is deleted in its entirety and replaced with the following: 
 (b) Termination by
the Company Without Cause or by the Executive for Good Reason. During the Term, if the Executive’s employment is terminated by the Company without Cause as provided in Section 3(d), or the Executive terminates his employment for Good
Reason as provided in Section 3(e), then the Company shall pay the Executive his Accrued Benefit. In addition, subject to the Executive signing a separation agreement containing, among other provisions, a general release of claims in favor of
the Company and related persons and entities, confidentiality, return of property and non-disparagement, in a form and manner satisfactory to the Company (the “Separation Agreement and Release”) and
the Separation Agreement and Release becoming irrevocable, all within 60 days after the Date of Termination: 
 (i) the
Company shall pay the Executive a lump sum in cash in an amount equal to twelve (12) months’ Base Salary (the “Severance Amount”); and 

 (ii) if the Executive was participating in the Company’s group health
plan immediately prior to the Date of Termination and elects COBRA health continuation, then the Company shall pay to the Executive a monthly cash payment for twelve (12) months or the Executive’s COBRA health continuation period,
whichever ends earlier, in an amount equal to the monthly employer contribution that the Company would have made to provide health insurance to the Executive if the Executive had remained employed by the Company; and 

(iii) upon the Date of Termination, all stock options and other stock-based awards held by the Executive in which the
Executive would have vested if he had remained employed for an additional twelve (12) months following the Date of Termination shall vest and become exercisable or nonforfeitable as of the Date of Termination; and 

(iv) The amounts payable under this Section 4(b) shall be paid or commence to be paid within 60 days after the Date of
Termination; provided, however, that if the 60-day period begins in one calendar year and ends in a second calendar year, such payment shall be paid or commence to be paid in the second calendar year by the
last day of such 60-day period. Each payment pursuant to this Agreement is intended to constitute a separate payment for purposes of Treasury Regulation
Section 1.409A-2(b)(2). 
 2. Each use of the phrase “twelve months” in the first
paragraph of Section 5 of the Employment Agreement is deleted and replaced with “fifteen (15) months.” 
 3. Section
5(a) of the Employment Agreement is deleted in its entirety and replaced with the following: 
 (a) Change in Control.
During the Term, if within fifteen (15) months after a Change in Control, the Executive’s employment is terminated by the Company without Cause as provided in Section 3(d) or the Executive terminates his employment for Good Reason as
provided in Section 3(e), then, subject to the signing of the Separation Agreement and Release by the Executive and the Separation Agreement and Release becoming irrevocable and fully effective, all within 60 days after the Date of Termination:

 (i) the Company shall pay the Executive a lump sum in cash in an amount equal to 1.5 times the sum of (A) the
Executive’s current Base Salary (or the Executive’s Base Salary in effect immediately prior to the Change in Control, if higher) plus (B) the Executive’s Target Annual Incentive Compensation; and 

(ii) except as otherwise expressly provided in any applicable option agreement or other stock-based award agreement, all stock
options and other stock-based awards held by the Executive subject to time-based vesting shall immediately accelerate and become fully exercisable or nonforfeitable as of the Date of Termination; and 

  
 - 2 - 

 (iii) if the Executive was participating in the Company’s group health
plan immediately prior to the Date of Termination and elects COBRA health continuation, then the Company shall pay to the Executive a monthly cash payment for eighteen (18) months or the Executive’s COBRA health continuation period,
whichever ends earlier, in an amount equal to the monthly employer contribution that the Company would have made to provide health insurance to the Executive if the Executive had remained employed by the Company; and 

(iv) The amounts payable under this Section 5(a) shall be paid or commence to be paid within 60 days after the Date of
Termination; provided, however, that if the 60-day period begins in one calendar year and ends in a second calendar year, such payment shall be paid or commence to be paid in the second calendar year by the
last day of such 60-day period. 
 4. Except to the extent expressly modified or amended by this
Amendment, all terms and provisions of the Employment Agreement shall continue in full force and effect and shall remain enforceable and binding in accordance with their respective terms. For purposes of clarity, this Amendment is not intended
to, and does not, supersede or negate or otherwise affect the Company’s rights under the any pre-existing proprietary inventions assignment agreement or
non-competition agreement that Executive had entered into prior to the Amendment Effective Date including the Restrictive Covenants which Executive hereby reaffirms as material terms of this Amendment. Neither
Party has made any representation to the other regarding any of the subject matters hereof except as expressly set forth in this Amendment. 

5. Any required notices, meetings or consents that are necessary to make an amendment to the Employment Agreement are hereby waived or
satisfied. 
 6. This Amendment may be executed in counterparts, each of which shall be deemed an original, but all of which together shall
be deemed to be one and the same agreement. A signed copy of this Amendment delivered by facsimile, e-mail or other means of electronic transmission shall be deemed to have the same legal effect as delivery of
an original signed copy of this Amendment. 
 * * * * * 

  
 - 3 - 

 IN WITNESS WHEREOF, the undersigned have executed this Amendment effective as of the date
first set forth above. 
  

			
	COMPANY:
	
	AERPIO PHARMACEUTICALS, INC.,
	a Delaware corporation

 
			
		
	By:	 	/s/ Steve Prelack

 
			
	Name:	 	Steve Prelack
	Title:	 	Director

  

			
	EXECUTIVE:

 
			
		
	By:	 	/s/ Joseph Gardner

 
			
	Name:	 	Joseph Gardner

  

  
 Signature Page to
Amendment No. 2 to Employment AgreementExhibit
10.1

 

QUANTA,
INC.

SUBSCRIPTION
AGREEMENT

S-1
SHARES

 

THIS
SUBSCRIPTION AGREEMENT made as of the _____ day of __________________, 2021 between QUANTA, INC., a corporation organized
under the laws of the State of Nevada, (the “Company”), and the undersigned (the “Subscriber”
and together with each of the other subscribers in the Offering (defined below), the “Subscribers”).

 

WHEREAS,
the Company desires to sell registered S-1 shares of its common stock (collectively, the “Shares”) (the
“Offering”), at a purchase price of $0.25 per Share and per the terms set forth in the Company’s
S-1 Registration Statement (as amended) which was originally filed on ______________ and declared Effective by the SEC on __________________.

 

NOW,
THEREFORE, for and in consideration of the promises and the mutual covenants hereinafter set forth, the parties hereto do
hereby agree as follows:

 

1.1.
Subscription for Shares. Subject to the terms and conditions hereinafter set forth, the Subscriber hereby subscribes for
and agrees to purchase from the Company such aggregate amount of Shares as is set forth upon the signature page hereof; and the
Company agrees to sell such Shares to the Subscriber for said purchase price subject to the Company’s right to sell to the
Subscriber such lesser number of Shares as the Company may, in its sole discretion, deem necessary or desirable. The purchase
price is payable by wire transfer, or certified or bank checks made payable to “QUANTA, INC.” and delivered contemporaneously
with the execution and delivery of this Subscription Agreement to the Company’s address set forth in the S-1.

 

1.2.
S-1 Registered Shares. The Subscriber acknowledges that the Shares being purchased herein are shares of common stock registered
in the Company’s S-1 (as amended) which was originally filed on _______________.

 

1.3.
Investment Purpose. The Subscriber represents that the Shares (the “Securities”) are being purchased
for his or her or its own account, for investment purposes only and not for distribution or resale to others in contravention
of the registration requirements of the 1933 Act. The Subscriber agrees that it will not sell or otherwise transfer the Securities
unless they are registered under the 1933 Act or unless an exemption from such registration is available.

 

1.4.
Accredited Investor. The Subscriber represents and warrants that he, she or it is an “accredited investor”
as such term is defined in Rule 501 of Regulation D promulgated under the 1933 Act, and that it is able to bear the economic risk
of any investment in the Shares.

 

1.5.
RISK OF INVESTMENT. THE SUBSCRIBER RECOGNIZES THAT THE PURCHASE OF THE SHARES INVOLVES A HIGH DEGREE OF RISK INCLUDING, WITHOUT
LIMITATION, ANY AND ALL RISKS DISCUSSED IN THIS SUBSCRIPTION AGREEMENT. AN INVESTMENT IN THE COMPANY AND THE SHARES MAY RESULT
IN THE LOSS OF A SUBSCRIBER’S ENTIRE INVESTMENT.

 

(a)
Risk of Loss of Investment. An investment in the Company and the Shares offered hereby involve a high degree of risk. An
investment in the Shares is suitable only for investors who can bear a loss of their entire investment.

 

(b)
Value of Shares is Speculative. The terms of this offering have been determined arbitrarily by the Company. There is no
relationship between such terms and the Company’s assets, earnings, book value and/or any other objective criteria of value.

 

    	 

    	 

    

 

(c)
Dependence on Net Proceeds; No Minimum Offering. The Company is dependent upon the net proceeds of this Offering to fund
its operations, as more specifically described elsewhere in this Subscription Agreement. There is no commitment by any person
to purchase Shares and there is no assurance that any number of Shares will be sold. Additionally, there is no minimum amount
of funds that are required to be raised in order for the Company to accept subscriptions received from investors and the Company’s
may terminate this Offering prior to the expiration of the Offering Period. There is no assurance that the Company will sell a
sufficient number of Shares in this Offering on a timely basis or that the net proceeds after payment of debts and other obligations
will be adequate for the Company’s needs.

 

(d)
Need for Additional Capital; Additional Private Placement. The net proceeds raised by the Company from this Offering will
be used immediately to fund the Company’s current operations. The Company will therefore require significant additional
financing shortly after this Offering, regardless of the net proceeds received, in order to satisfy its cash requirements. The
Company may seek to raise additional funds in private placement transactions. However, there is no assurance that it will be able
to do so in a timely manner or on terms that will enable it to enter its proposed business on a reasonable basis.

 

1.6
Reserved.

 

1.7
Information. The Subscriber acknowledges receipt and full and careful review and understanding of this Subscription Agreement
and of the S-1 (as amended) which was originally filed on ______________.

 

1.8
No Representations or Warranties. The Subscriber hereby represents that, except as expressly set forth in the S-1, no representations
or warranties have been made to the Subscriber by the Company or any agent, employee or affiliate of the Company and in entering
into this transaction the Subscriber is not relying on any information other than that contained in the S-1 and the results of
independent investigation by the Subscriber.

 

1.9
Tax Consequences. The Subscriber acknowledges that this Offering of the Shares may involve tax consequences and that the
contents of the S-1 does not contain tax advice or information. The Subscriber acknowledges that it must retain its own professional
advisors to evaluate the tax and other consequences of an investment in the Shares.

 

1.10
Transfer or Resale. The Subscriber understands that the Shares purchased herein were qualified in the S-1 under the Securities
Act of 1933 Act, but that Subscriber will be required by the transfer agent or Subscriber’s brokerage firm to obtain a legal
opinion from securities counsel to deposit and sell the Shares.

 

2.1
Organization and Registration. The Company and its “Subsidiaries” (which for purposes of this
Subscription Agreement means any entity in which the Company, directly or indirectly, owns capital stock and holds a majority
or similar interest) are duly organized and validly existing in good standing under the laws of the jurisdiction in which they
were organized, and have the requisite power and authorization to own their properties and to carry on their business as now being
conducted.

 

2.2
Authorization; Enforcement; Validity. The Company has the requisite corporate power and authority to enter into and perform
its obligations under this Subscription Agreement and to issue the Securities in accordance with the terms of the S-1.

 

3.1
Closing and Termination of Offering. Provided that the required conditions to closing set forth herein have been satisfied
or waived, a closing (the “Initial Closing”) shall take place at the offices of the Company as set forth
herein or at such place as may otherwise be agreed to by the Company within 30 days of the receipt of the first cleared subscriber’s
funds. The Company may consummate subsequent closings of the Offering, upon mutual agreement only, each of which shall be subject
to satisfaction or waiver of the conditions to closing set forth herein, and each of which shall be deemed a “Closing”
hereunder.

 

    	 

    	 

    

 

4.1
The obligation of the Company hereunder to issue and sell Shares to the Subscriber at the Closing is subject to the satisfaction,
at or before the Closing, of each of the following conditions, provided that these conditions are for the Company’s sole
benefit and may be waived by the Company at any time in its sole discretion by providing the Subscriber with prior written notice
thereof:

 

4.2
Execution and Delivery. The Subscriber shall have executed this Subscription Agreement and delivered the same to the Company.

 

4.3
Purchase Price. The Subscriber shall have paid the purchase price for the Shares being purchased by the Subscriber at the
Closing in the manner set forth in Section 1.1.

 

4.4
Representations and Warranties. The representations and warranties of the Subscriber shall be true and correct in all material
respects as of the date when made and as of the Closing as though made at that time, and the Subscriber shall have performed,
satisfied and complied in all material respects with the covenants, agreements and conditions required by this Subscription Agreement
to be performed, satisfied or complied with by the Subscriber at or prior to the Closing.

 

4.5
Other Matters. All opinions, certificates and documents and all proceedings related to this Offering shall be in form and
content reasonably satisfactory to the Company and its legal counsel.

 

4.6
Notice. Any notices, consents, waivers or other communications required or permitted to be given under the terms of this
Subscription Agreement must be in writing and will be deemed to have been delivered: (a) upon receipt, when delivered personally,
(b) upon receipt, when sent by facsimile (provided confirmation of transmission is mechanically or electronically generated and
kept on file by the sending party), or (c) one (1) business day after deposit with an overnight courier service, in each case
properly addressed to the party to receive the same. The addresses and facsimile numbers for such communications shall be:

 

If
to the Company at the address set forth in the S-1, Attn. Eric Rice, CEO.

 

If
to the Subscriber, to its address and email or facsimile number set forth at the end of this Subscription Agreement, or to such
other address and/or facsimile number and/or to the attention of such other person as specified by written notice given to the
Company five (5) days prior to the effectiveness of such change.

 

Written
confirmation of receipt (a) given by the recipient of such notice, consent, waiver or other communication, (b) mechanically or
electronically generated by the sender’s facsimile machine containing the time, date, recipient facsimile number and an
image of the first page of such transmission, or (c) provided by an overnight courier service shall be rebuttable evidence of
personal service, receipt by facsimile or receipt from an overnight courier service in accordance with clauses (a), (b) or (c)
above, respectively.

 

4.7
Entire Agreement; Amendment. This Subscription Agreement supersedes all other prior oral or written agreements between
the Subscriber, the Company, their affiliates and persons acting on their behalf with respect to the matters discussed herein,
and this Subscription Agreement and the instruments referenced herein contain the entire understanding of the parties with respect
to the matters covered herein and therein and, except as specifically set forth herein or therein, neither the Company nor the
Subscriber makes any representation, warranty, covenant or undertaking with respect to such matters.

 

4.8
Severability. If any provision of this Subscription Agreement shall be invalid or unenforceable in any jurisdiction, such
invalidity or unenforceability shall not affect the validity or enforceability of the remainder of this Subscription Agreement
in that jurisdiction or the validity or enforceability of any provision of this Subscription Agreement in any other jurisdiction.

 

    	 

    	 

    

 

4.9
Governing Law; Jurisdiction. This Agreement shall be governed by and construed solely in accordance with the internal laws
of the State of Nevada with respect to contracts executed, delivered and to be fully performed therein, without regard to the
conflicts of laws principles thereof. The parties hereto hereby expressly and irrevocably agree that any suit or proceeding arising
under this Agreement or the consummation of the transactions contemplated hereby, shall be brought solely in a federal or state
court located in the State of Nevada. By its execution hereof, Company and Subscriber hereby expressly and irrevocably submits
to the in personam jurisdiction of the federal and state courts located in the State of Nevada and agree that any
process in any such action may be served upon him or her personally, or by certified mail or registered mail upon such party or
such agent, return receipt requested, with the same full force and effect as if personally served upon such party in Nevada. The
parties hereto each waive any claim that any such jurisdiction is not a convenient forum for any such suit or proceeding and any
defense or lack of in personam jurisdiction with respect thereto. In the event of any such action or proceeding,
the party prevailing therein shall be entitled to payment from the other party hereto of its reasonable counsel fees and disbursements.

 

4.10
Headings. The headings of this Subscription Agreement are for convenience of reference and shall not form part of, or affect
the interpretation of, this Subscription Agreement.

 

4.11
Successors And Assigns. This Subscription Agreement shall be binding upon and inure to the benefit of the parties and their
respective successors and assigns, including any purchasers of the Shares. The Company shall not assign this Subscription Agreement
or any rights or obligations hereunder. Subscriber may assign some or all of its rights hereunder without the consent of the Company,
provided, however, that any such assignment shall not release the Subscriber from its obligations hereunder unless
such obligations are assumed by such assignee and the Company has consented to such assignment and assumption, which consent shall
not be unreasonably withheld.

 

4.12
No Third-Party Beneficiaries. This Subscription Agreement is intended for the benefit of the parties hereto and their respective
permitted successors and assigns, and is not for the benefit of, nor may any provision hereof be enforced by, any other person.

 

4.13
Survival. The representations and warranties of the Company and the Subscriber contained in herein shall survive the Closing
for a period of twelve (12) months.

 

4.14
Legal Representation. The Subscriber acknowledges that: (a) it has read this Subscription Agreement and the exhibits hereto;
(b) it understands that the Company has been represented in the preparation, negotiation, and execution of this Subscription Agreement
by counsel to the Company; (c) it has either been represented in the preparation, negotiation, and execution of this Subscription
Agreement by legal counsel of its own choice, or has chosen to forego such representation by legal counsel after being advised
to seek such legal representation; and (d) it understands the terms and consequences of this Subscription Agreement and is fully
aware of its legal and binding effect.

 

4.15
Confidentiality. The Subscriber agrees that it shall keep confidential and not divulge, furnish or make accessible to anyone,
the confidential information concerning or relating to the business or financial affairs of the Company contained in the S-1 to
which it has become privy by reason of this Subscription Agreement.

 

4.16
Counterparts. This Subscription Agreement may be executed in two or more identical counterparts, all of which shall be
considered one and the same agreement and shall become effective when counterparts have been signed by each party and delivered
to the other party; provided that a facsimile signature shall be considered due execution and shall be binding upon the signatory
thereto with the same force and effect as if the signature were an original, not a facsimile signature.

 

Signature
Page Follows

Remainder
of Page Intentionally Left Blank

 

    	 

    	 

    

 

IN
WITNESS WHEREOF, the undersigned Subscriber(s) have executed this QUANTA, INC. Subscription Agreement for S-1 Shares as of
the date first written above. The Company’s acceptance of such subscription is as of the date shown below.

 

	SUBSCRIBER
    **	 	CO-SUBSCRIBER
    **
	 	 	 
	 	 	 
	Signature
    of Subscriber	 	Signature
    of Co-Subscriber
	 	 	 
	 	 	 
	Name
    of Subscriber [please print]	 	Name
    of Co-Subscriber [please print]
	 	 	 
	 	 	 
	Address
    of Subscriber	 	Address
    of Co-Subscriber
	 	 	 
	 	 	 
	Social
        Security or Taxpayer

        Identification
        Number of Subscriber
	 	Social
        Security or Taxpayer Identification

        Number
        of Co-Subscriber

 

Name
of Holder(s) as it should appear on the security certificates* [please print]

 

*
Please provide the exact names that you wish to see on the certificates

 

(1)
For individuals, print full name of subscriber.

(2)
For joint, print full name of subscriber and all co-subscribers.

(3)
For corporations, partnerships, LLC, print full name of entity, including “&,” “Co.,” “Inc.,”
“etc,” “LLC,” “LP,” etc.

(4)
For Trusts, print trust name (please contact your trustee for the exact name that should appear on the certificates.)

 

Dollar
Amount of Shares Subscribed For: $_________________

 

	 	 	 	Dollar
    Amount of
	 	 	 	Subscription
    Accepted: $___________________
	 	 	 	 
	 	 	 	SUBSCRIPTION
    ACCEPTED BY THE COMPANY
	 	 	 	 	 
	 	 	 	QUANTA,
    INC.
	 	 	 	 	 
	Date:	 	 	By:	 
	 	To
Be Dated by Company Upon Acceptance	 	 	Arthur
    Mikaelian, CEO

 

**If
Subscriber is a Registered Representative with an FINRA member firm or an affiliated person of an FINRA member firm, have the
acknowledgment to the right signed by the appropriate party:

 

The
undersigned FINRA Member firm acknowledges receipt of the notice required by Rule 3040 of the FINRA Conduct Rules.

 

Name
of FINRA Member Firm

 

	By:	 	 
	 	Authorized Officer

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