Document:

Exhibit 10.4

 

May 30, 2017

 

Via
Email and Hand Delivery

M. Scott Salka

 

 

Dear Scott:

 

This letter sets forth
the substance of our agreement (the “Agreement”) regarding your separation from AmpliPhi Biosciences
Corporation (the “Company”). This Agreement will become effective upon the Effective Date specified in
Section 11 below.

 

1.                 
Separation. You resign effective May 31, 2017 (the “Separation Date”) from any
and all employment with the Company, and your status as an employee of the Company will end on that date. Provided that this Agreement
becomes effective as specified in Section 11 and that you satisfy the requirements of Section 2 hereof, the Company will provide
you with the following benefits after the Separation Date: (i) continued payment of your base salary for twelve (12) months following
the Separation Date, through May 31, 2018 (the “Severance Period”), beginning with the first regularly-scheduled
payroll date following the Effective Date; (ii) grant you, subject to approval by the Board and vesting as specified in Section
2 hereof, an option under the Company’s 2016 Equity Incentive Plan (the “Plan”) to purchase 50,000
shares of the Company’s common stock at an exercise price equal to the fair market value on the date of grant (the “Option”)
as determined in accordance with the Plan; and (iii) direct payment of COBRA premiums on your behalf, provided that you timely
elect continued health insurance coverage pursuant to COBRA, through the earlier of the following: a) the duration of the Severance
Period; b) the date upon which you become eligible for health insurance pursuant to another employer-sponsored group health insurance
plan; or c) the date upon which you become ineligible for continued coverage under COBRA (collectively, the “Separation
Benefits”). In accordance with your employment offer letter agreement with the Company of April 24, 2015 (the “Employment
Agreement”), your resignation of employment also constitutes resignation from the Company’s Board of Directors
(the “Board”).

 

2.                 
Consultancy. The Company agrees to retain you as a consultant, and you agree to provide consulting services,
under the terms specified below.

 

a.     
Consulting Period. The consulting relationship shall commence on the Separation Date and continue until
the earlier of: (i) the 90th day after the Separation Date; (ii) in the event you breach your Post-Employment Obligations
(as defined in Section 2(d) below), the date of any such breach; (iii) a date mutually agreed between you and the Company; or (iv)
the date terminated by the Company (the “Consulting Period”).

 

b.     
Consulting Services. You agree to make yourself reasonably available to provide consulting services to
the Board consistent with your expertise and experience and primarily directed to the transition of executive leadership within
the Company through the end of the Consulting Period (the “Consulting Services”). You agree to exercise
the highest degree of professionalism and utilize your expertise and creative talents to the fullest in performing the Consulting
Services. Your relationship with the Company during the Consulting Period will be that of an independent contractor, and nothing
in this Agreement is intended to, or should be construed to, create a partnership, agency, joint venture or employment relationship
after the Separation Date.

 

     

     

    

 

c.      
Option Vesting and Exercise. Provided that you satisfy all conditions of this Section 2 and the “Post-Employment
Obligations” (defined below) the Option shall vest at the conclusion of the Consulting Period. Once vested, and subject to
your satisfaction of the Post-Employment Obligations, you shall have the right to exercise all or part of the Option for a period
of three years following the Consulting Period. In the event the Company terminates the Consulting Period for reasons other than
your violation of the Post-Employment Obligations, the Option shall immediately vest and be fully exercisable on the effective
date of such termination. You are advised by the Company to seek independent legal advice with respect to tax and securities law
issues regarding the Option and any sale of Company stock.

 

d.     
Protection of Confidential and Proprietary Information, Non-Compete Period. You acknowledge your obligations
and promises to the Company pursuant to your Proprietary Information and Invention Assignment Agreement with the Company (the “Post-Employment
Obligations”) and you agree that the Post-Employment Obligations shall continue to apply in full force and effect
during the Consulting Period and thereafter. Any and all work product you create in connection with the Consulting Services will
be the sole and exclusive property of the Company. You hereby assign to the Company all right, title, and interest in all inventions,
techniques, processes, materials, and other intellectual property developed in the course of performing the Consulting Services.

 

e.      
Authority and Facilities Usage During Consulting Period. After the Separation Date, you will have no authority
to bind the Company (or to represent that you have authority to bind the Company) to any contractual obligations, whether written,
oral or implied. You hereby agree that after the Separation Date, you will not represent or purport to represent the Company in
any manner to any third party. Access to and use of Company facilities or equipment to perform the Consulting Services will be
coordinated through the Board.

 

f.       
Breach of Obligations. If you breach your Post-Employment Obligations or the nondisparagement obligations
of this Agreement the vesting of the Option and your right to exercise the Option shall be extinguished and the Option shall lapse.
Nothing in this paragraph waives the Company’s right to pursue other action against you for any breach of your obligations
under this Agreement or the Employment Agreement.

 

3.                 
Accrued Salary and Vacation. On the Separation Date, the Company shall pay you all accrued salary, and
all accrued and unused vacation, earned through the Separation Date, subject to standard payroll deductions and withholdings. You
are entitled to these payments by law.

 

4.                 
Prior Equity Awards. All stock options to purchase common stock of the Company that were previously granted
to you by the Company, other than the stock option granted to you on April 1, 2017 (which option is exercisable, after giving effect
to the Company’s 1-for-10 reverse stock split effected on April 24, 2017, for 21,421 shares at an exercise price of $4.30
per share and has a four-year exercise term), are hereby terminated and all shares subject to said options shall be returned to
the pool available for grant pursuant to the Plan.

 

    	 	 2	 

     

    

 

5.                 
Other Compensation or Benefits. You acknowledge that, except as expressly provided in this Agreement,
you will not receive any additional compensation, severance or benefits after the Separation Date. For the avoidance of doubt,
you and the Company acknowledge that you will be paid on the Separation Date if not previously paid (i) your annual performance
bonus for 2016, based on the extent to which the goals previously established for such bonus were achieved, as determined by the
Board or Compensation Committee in its sole discretion, and (ii) the entire bonus payment to which you are entitled pursuant to
Section 4 of that certain amendment to the Employment Agreement between you and the Company, dated April 1, 2017.

 

6.                 
Expense Reimbursement. You agree that, no later than thirty (30) days following the Separation Date, you
will submit your final documented employee expense reimbursement statement reflecting all business expenses you incurred through
the Separation Date, if any, for which you seek reimbursement and the Company agrees to reimburse all reasonable and appropriate
expenses pursuant to its policies and practices.

 

7.                 
Return of Company Property. You hereby represent that you will, not later than the Separation Date, perform
a good faith search for, and return to the Company, all Company documents (and all copies thereof) and other Company property in
your possession or control, including, but not limited to, Company files, correspondence, memoranda, notes, notebooks, drawings,
books and records, plans, forecasts, reports, proposals, studies, agreements, financial information, personnel information, sales
and marketing information, research and development information, systems information, specifications, computer-recorded information,
tangible property and equipment, credit cards, entry cards, identification badges and keys; and any materials of any kind that
contain or embody any proprietary or confidential information of the Company (and all reproductions thereof in whole or in part)
(“Company Property”); provided, however, that the foregoing shall not apply to information and documentation
you received solely in your capacity as a member of the Board, or as a shareholder, option holder or restricted stock unit holder
of the Company, or as a participant in any employee benefit plan that the Company sponsors.

 

8.                 
Nondisparagement; Communication. You agree not to disparage the Company or its officers, directors, employees,
shareholders and agents in any manner likely to be harmful to its or their business, business reputation or personal reputation.
The Company agrees that the Company’s directors and officers shall not disparage you to any third party in any manner likely
to be harmful to your business or personal reputation. Notwithstanding the foregoing, both you and the Company may respond accurately
and fully to any question, inquiry or request for information when required by legal process. The Company will provide you a reasonable
opportunity to review in advance its formal announcement of this Agreement and will endeavor in good faith to reach agreement with
respect to your suggestions regarding the content of same.

 

9.                 
Cooperation and Assistance.  You agree that you will not voluntarily provide assistance, information,
encouragement, or advice, directly or indirectly (including through agents or attorneys), to any person or entity in connection
with any claim by or against the Company, nor shall you induce or encourage any person or entity to do so. The foregoing sentence
shall not prohibit you from testifying truthfully under subpoena. You warrant that you have not previously provided assistance,
information, encouragement, or advice, directly or indirectly, to any person or entity in connection with any claim by or against
the Company. You agree to provide (voluntarily and without legal compulsion) prompt cooperation and accurate and complete information
to the Company in the event of litigation involving the Company or its officers or directors and to respect and preserve all privileges
held by or available to the Company.

 

    	 	 3	 

     

    

 

10.             
Release.  In exchange for the consideration provided to you by this Agreement that you are not otherwise
entitled to receive, you hereby generally and completely release the Company and its directors, officers, employees, shareholders,
members, partners, agents, attorneys, predecessors, successors, parent and subsidiary entities, insurers, affiliates, and assigns
from any and all claims, liabilities and obligations, both known and unknown, that arise out of or are in any way related to events,
acts, conduct, or omissions occurring prior to your signing this Agreement. This general release includes, but is not limited to:
(1) all claims arising out of or in any way related to your employment with the Company or the termination of that employment;
(2) all claims related to your compensation or benefits from the Company, including, but not limited to, salary, bonuses, commissions,
vacation pay, expense reimbursements, severance pay, fringe benefits, stock, stock options, or any other ownership interests in
the Company; (3) all claims for breach of contract, wrongful termination, and breach of the implied covenant of good faith
and fair dealing; (4) all tort claims, including, but not limited to, claims for fraud, defamation, emotional distress, and
discharge in violation of public policy; and (5) all federal, state, and local statutory claims, including, but not limited to,
claims for discrimination, harassment, retaliation, attorneys’ fees, or other claims arising under the federal Civil Rights
Act of 1964 (as amended), and the federal Americans with Disabilities Act of 1990, the federal Age Discrimination in Employment
Act of 1967 (as amended) (“ADEA”). The claims described above that you are releasing do not include:
(1) any rights which cannot be waived as a matter of law; (2) any claims arising from breach of this Agreement; (3) any rights
or claims for indemnification you may have pursuant to any written indemnification agreement with the Company to which you are
a party, the Company’s bylaws, or applicable law; (4) any rights or claims to benefits under Company benefit plans or programs
to which you have a vested or non-forfeitable right at the time of your separation; (5) any rights or claims that you may have
after separation pursuant to stock options or restricted stock units that have vested or been granted or issued prior to or at
the time of your separation; or (6) any rights or claims to insurance coverage under insurance policies maintained by the Company
for directors, executives, and/or officers.  Nothing in this Agreement prevents you from filing a charge or complaint with
the Equal Employment Opportunity Commission, the National Labor Relations Board, the Occupational Safety and Health Administration,
the Securities and Exchange Commission or any other federal, state or local governmental agency or commission (collectively, the
“Government Agencies”). You understand this Agreement does not limit your ability to communicate with
any Government Agencies or otherwise participate in any investigation or proceeding that may be conducted by any Government Agency,
including providing documents or other information, without notice to the Company.  While this Agreement does not limit your
right to receive an award for information provided to the Securities and Exchange Commission, you understand and agree that, to
the maximum extent permitted by law, you are otherwise waiving any and all rights you may have to individual relief based on any
claims that you have released and any rights you have waived by signing this Agreement.

 

    	 	 4	 

     

    

 

11.             
ADEA Waiver. You acknowledge that you are knowingly and voluntarily waiving and releasing any rights you
may have under ADEA, and that the consideration given for the waiver and release in the preceding paragraph is in addition to anything
of value to which you were already entitled. You further acknowledge that you have been advised by this writing that: (a)
your waiver and release do not apply to any rights or claims that may arise after the execution date of this Agreement; (b)
you should consult with an attorney prior to executing this Agreement; (c)
you have twenty-one (21) days after the date of your receipt of this Agreement to consider this Agreement (although you may choose
to voluntarily execute this Agreement earlier); (d) you have seven
(7) days following the execution of this Agreement by the parties to revoke the Agreement; and (e) this
Agreement will not be effective until the date upon which the revocation period has expired without your having revoked (the “Effective
Date”), and you will not receive the benefits specified by this Agreement unless and until it becomes effective.

 

12.             
Disputes. Any dispute or controversy between you and the Company, arising out of or relating to this Agreement,
the breach of this Agreement, your employment or consulting to the Company, or otherwise, shall be settled by binding arbitration
conducted by and before a single arbitrator in San Diego, California administered by JAMS in accordance with its Employment Arbitration
Rules (the “JAMS Rules”) then in effect and judgment on the award rendered by the arbitrator may be entered
in any court having jurisdiction thereof. Both you and the Company hereby waive the right to a trial by jury or judge, or by administrative
proceeding, for any covered claim or dispute. To the extent the JAMS Rules conflict with any provision or aspect of this Agreement,
this Agreement shall control. The arbitrator shall have the authority to award any remedy or relief that a court of competent jurisdiction
could order or grant, including, without limitation, the issuance of an injunction. However, either party may, without inconsistency
with this arbitration provision, apply to any court having jurisdiction over such dispute or controversy and seek interim provisional,
injunctive or other equitable relief until the arbitration award is rendered or the controversy is otherwise resolved. Except as
necessary in court proceedings to enforce this arbitration provision or an award rendered hereunder, or to obtain interim relief,
neither a party nor an arbitrator may disclose the existence, content or results of any arbitration hereunder without the prior
written consent of the Company and you. All claims, disputes, or causes of action under this Agreement, whether by you or the Company,
must be brought in an individual capacity, and shall not be brought as a plaintiff (or claimant) or class member in any purported
class or representative proceeding, nor joined or consolidated with the claims of any other person or entity. The arbitrator may
not consolidate the claims of more than one person or entity, and may not preside over any form of representative or class proceeding.
This Agreement is made under the provisions of the Federal Arbitration Act (9 U.S.C., Sections 1-14) (“FAA”)
and will be construed and governed accordingly. It is the parties’ intention that both the procedural and the substantive
provisions of the FAA shall apply. Questions of arbitrability (that is whether an issue is subject to arbitration under this agreement)
shall be decided by the arbitrator. Likewise, procedural questions which grow out of the dispute and bear on the final disposition
are also matters for the arbitrator. However, where a party already has initiated a judicial proceeding, a court may decide procedural
questions that grow out of the dispute and bear on the final disposition of the matter. Each party shall bear its or his costs
and expenses in any arbitration hereunder and one-half of the arbitrator’s fees and costs; provided, however, that the arbitrator
shall have the discretion to award the prevailing party reimbursement of its or his reasonable attorney’s fees and costs,
unless such award is prohibited by applicable law. Notwithstanding the foregoing, you and the Company shall each have the right
to resolve any dispute or cause of action involving trade secrets, proprietary information, or intellectual property (including,
without limitation, inventions assignment rights, and rights under patent, trademark, or copyright law) by court action instead
of arbitration.

 

    	 	 5	 

     

    

 

13.             
Miscellaneous. This Agreement, together with the continuing obligations under the Employment Agreement
described herein, constitutes the complete, final and exclusive embodiment of the entire agreement between you and the Company
with regard to this subject matter. It is entered into without reliance on any promise or representation, written or oral, other
than those expressly contained herein, and it supersedes any other such promises, warranties or representations. This Agreement
may not be modified or amended except in a writing signed by both you and an authorized member of the Board. This Agreement will
bind the heirs, personal representatives, successors and assigns of both you and the Company, and inure to the benefit of both
you and the Company, their heirs, successors and assigns. The failure to enforce any breach of this Agreement shall not be deemed
to be a waiver of any other or subsequent breach. For purposes of construing this Agreement, any ambiguities shall not be construed
against either party as the drafter. If any provision of this Agreement is determined to be invalid or unenforceable, in whole
or in part, this determination will not affect any other provision of this Agreement and the provision in question will be modified
so as to be rendered enforceable in a manner consistent with the intent of the parties insofar as possible. This Agreement will
be deemed to have been entered into and will be construed and enforced in accordance with the laws of the State of California as
applied to contracts made and to be performed entirely within California. This Agreement may be executed in counterparts or with
facsimile signatures, which shall be deemed equivalent to originals.

 

If this Agreement is acceptable to you, please
sign below and return one original to me.

 

 

	Sincerely,	 	 
	 	 	 
	AmpliPhi Biosciences Corporation	 	 
	 	 	 	 	 
	By: 	/s/ Dr. Michael S. Perry	 	 	 
	  	Dr. Michael S. Perry, on behalf of the Board of Directors	 	 	 
	      	 	 	 	 
	 	 	 	 	 
	Agreed and Accepted:	 	 	 
	 	 	 	 
	 	 	 	 
	/s/ M. Scott Salka 	 	31 May 2017	 
	M. Scott Salka	 	Date	 

 

    	 	 6Exhibit 10.5

 

 

June 1, 2017

 

Paul C. Grint, M.D.

7757 Doug Hill Court

San Diego, CA 92127

 

Dear Paul:

 

We are pleased to confirm our
offer of employment with AmpliPhi Biosciences Corporation (the “Company”), in the position of Chief Executive
Officer (“CEO”) on the terms set forth in this letter agreement (the “Agreement”).

 

1.                  
Position. As CEO, you will be responsible for managing the day to day operations and strategy of the Company and will
report directly to the Board of Directors of the Company (the “Board”). You agree to devote your full
business time and attention to your work for the Company. Except upon the prior written consent of the Board, you will not, during
your employment with the Company, (i) accept or maintain any other employment, or (ii) engage, directly or indirectly, in any other
business activity (whether or not pursued for pecuniary advantage) that might interfere with your duties and responsibilities as
a Company employee or create a conflict of interest with the Company. Such consent will not be unreasonably withheld for up to
two director positions at companies that do not compete with the Company.

 

2.                  
Salary. Your initial base salary will be paid at the annualized rate of $475,000 per year on the Company’s regular
payroll dates and subject to approved deductions and required withholdings. Your salary will be reviewed from time to time by the
Board or its compensation committee, and may be adjusted in the sole discretion of the Board or its compensation committee.

 

3.                  
Bonus. You will be eligible to earn an annual performance bonus based on achievement of Company performance objectives
to be established by the Board or its compensation committee and provided to you. Your annual target performance bonus will initially
be equal to 50% of your base salary, although the amount of any payment will be dependent upon actual performance as determined
by the Board or its compensation committee. Generally, you must be employed by the Company through the date on which bonuses are
paid in order to be eligible to receive a bonus, however if your employment is terminated during the year for any reason other
than Cause (as defined below), you will remain eligible to be awarded a pro-rated portion of the performance bonus for the year
in which your termination occurred, based on achievement of Company performance objectives, as determined by the Board or its compensation
committee. Your annual target performance bonus, if any, shall be paid to you on or before March 15 of the year following the year
to which it relates. Your annual target performance bonus percentage is subject to modification from time to time in the discretion
of the Board or its compensation committee.

 

4.                   Equity
Award. Upon your commencement of employment with the Company and subject to approval by the Board and, if
deemed necessary, the Company’s shareholders, you will be granted an option under the Company’s 2016 Equity
Incentive Plan (the “Plan”) to purchase 475,189 shares of the Company’s common stock (the
“Option”). The Option shall vest over time with respect to 40% of the total number of shares (the
“Time-Based Shares”), conditioned upon your continuous service to the Company on the applicable
vesting dates, as follows: i) 25% of the Time Based Shares shall vest on the first anniversary of your commencement of
employment as the CEO and ii) thereafter the balance of the shares shall vest on the final day of each month in 36 equal
installments. With respect to 60% of the total number of shares (the “Performance-Based Shares”),
the Option shall vest based on the Board’s or its compensation committee’s determination of the achievement of
corporate performance criteria. The corporate performance criteria applicable to the Performance-Based Shares shall be
determined by the Board or its compensation committee, after consultation with you. The exercise price of the Option shall be
the fair market value of the Company’s common stock on the date of grant in accordance with the Plan and shall be
subject to the terms and conditions of the Plan, stock option grant notice and option agreement to be entered into
between you and the Company.

 

    	 

    	 Page 2 of 8	 

    

 

 

5.                  
Benefits. You will be eligible to participate in the benefits made generally available by the Company to its senior
executives, in accordance with the benefit plans established by the Company, and as may be amended from time to time in the Company’s
sole discretion.

 

6.                  
At-Will Employment. The Company is an “at-will” employer. Accordingly, either you or the Company may terminate
the employment relationship at any time, with or without advance notice, and with or without cause.

 

7.                  
Termination. Upon any termination of your employment, you will be deemed to have resigned, and you hereby resign, from
all offices and directorships, if any, then held with the Company or any subsidiary. In the event of termination of your employment
with the Company, regardless of the reasons for such termination, the Company shall pay your base salary and accrued but unused
vacation up to and through the date of termination, less applicable payroll and tax withholdings (the “Accrued Obligations”).

 

8.                  
Severance. You shall be eligible for the severance benefits described in this Section 8.

 

a.                  
In the event (i) the Company terminates your employment without Cause (as defined below and other than due to your death
or disability), or (ii) you terminate your employment for Good Reason (as defined below), and provided in either case of (i) or
(ii) such termination or resignation constitutes a “separation from service” (as defined under Treasury Regulation
Section 1.409A-1(h), without regard to any alternative definition thereunder, a “Separation from Service”)
(such termination or resignation, an “Involuntary Termination”), then, in addition to the Accrued Obligations,
subject to your obligations below, you shall be entitled to receive an amount equal to twelve (12) months of your then current
base salary (ignoring any decrease in base salary that forms the basis for Good Reason), less all applicable withholdings and deductions,
paid on the schedule described below (the “Severance Pay”).

 

b.                 
The Severance Pay is conditional upon (i) your continuing to comply with your obligations under your PIIA (as defined
in Section 11) during the period of time in which you are receiving the Severance Pay; (ii) your delivering to the Company an executed
separation agreement and general release of claims in favor of the Company, in a form attached hereto as Exhibit
A, within the time period set forth therein, which becomes effective in accordance with its terms, which shall be no later
than sixty (60) days following your Separation from Service (the “Release”). The Severance Pay will be
paid in equal installments on the Company’s regular payroll schedule over the period outlined above following the date of
your Separation from Service; provided, however, that no payments will be made prior to the sixtieth (60th) day
following your Separation from Service. On the sixtieth (60th) day following your Separation from Service, the Company
will pay you in a lump sum the amount of the Severance Pay that you would have received on or prior to such date under the original
schedule but for the delay while waiting for the sixtieth (60th) day, with the balance of the Severance Pay being paid
as originally scheduled.

 

    	 

    	 Page 3 of 8	 

    

 

c.                  
“Cause” for purposes of your Severance Pay means (i) your gross negligence or willful failure
substantially to perform your duties and responsibilities to the Company or deliberate violation of a Company policy; (ii) your
commission of any act of fraud, embezzlement or dishonesty against the Company or any other willful misconduct that has caused
or is reasonably expected to result in material injury to the Company; (iii) your unauthorized use or disclosure of any proprietary
information or trade secrets of the Company or any other party to whom you owe an obligation of nondisclosure as a result of your
relationship with the Company; or (iv) your willful breach of any of your obligations under any written agreement or covenant with
the Company, including without limitation this Agreement and your PIIA.

 

d.                 
“Good Reason” for purposes of your Severance Pay means the occurrence at any time of any of
the following without your prior written consent: (i) a material reduction in your authority, duties or responsibilities (other
than a mere change in title following any merger or consolidation of the Company with another entity); (ii) a material reduction
in your base salary; or (iii) any willful failure or willful breach by the Company of any of its material obligations under this
Agreement. For purposes of this subsection, no act, or failure to act, on the Company’s part shall be deemed “willful”
unless done, or omitted to be done, by the Company not in good faith and without reasonable belief that the Company’s act,
or failure to act, was in the best interest of the Company. In order to terminate your employment under this Agreement for Good
Reason, you must (1) provide written notice to the Company within ninety (90) days of the first occurrence of the events described
above, (2) allow the Company at least thirty (30) days from such receipt of such written notice to cure such event, and (3) if
such event is not reasonably cured within such period, resign from all position you then hold with the Company effective not later
than the one-hundred eightieth (180th) day after the initial occurrence of such event.

 

9.                  
Change in Control. If your Involuntary Termination occurs within one (1) month prior to, or twelve (12) months following
a Change in Control (as defined in the Plan), the vesting of all of your outstanding equity awards (including the Option) that
are subject to time-based vesting requirements (including the Time-Based Shares) shall accelerate in full such that all such equity
awards shall be deemed fully vested as of the date of such Involuntary Termination (or Change in Control, if later).

 

10.              
Taxes. All amounts paid under this Agreement shall be paid less all applicable state and federal tax withholdings (if
any) and any other withholdings required by any applicable jurisdiction or authorized by you.

 

a.                  
Section 409A. The Severance Pay provided in this Agreement is intended to qualify
for an exemption from application of Section 409A of the Internal Revenue Code of 1986, as amended (the “Code”)
and the regulations and other guidance thereunder and any state law of similar effect (collectively “Section 409A”)
or to comply with its requirements to the extent necessary to avoid adverse personal
tax consequences under Section 409A, and any ambiguities herein shall be interpreted accordingly. Each installment
of Severance Pay is a separate “payment” for purposes of Treasury Regulations Section 1.409A-2(b)(2)(i), and the Severance
Pay is intended to satisfy the exemptions from application of Section 409A provided under Treasury Regulations Sections 1.409A-1(b)(4),
1.409A-1(b)(5) and 1.409A-1(b)(9). However, if such exemptions are not available and you are, upon Separation from Service, a
“specified employee” for purposes of Section 409A, then, solely to the extent necessary to avoid adverse personal
tax consequences under Section 409A, the timing of the Severance Pay shall be delayed until the earlier of (i) six (6) months
and one day after your Separation from Service, or (ii) your death. Except to the minimum extent that payments must be delayed
because you are a “specified employee”, all amounts of Severance Pay will be paid as soon as practicable in accordance
with the schedule provided herein and in accordance with the Company’s normal payroll practices.

 

    	 

    	 Page 4 of 8	 

    

 

b.                 
Section 280G. If any payment or benefit you will or may receive from the Company or otherwise (a “280G Payment”)
would (i) constitute a “parachute payment” within the meaning of Section 280G of the Code, and (ii) but for this sentence,
be subject to the excise tax imposed by Section 4999 of the Code (the “Excise Tax”), then any such 280G
Payment pursuant to this Agreement or otherwise (a “Payment”) shall be equal to the Reduced Amount. The
“Reduced Amount” shall be either (x) the largest portion of the Payment that would result in no portion
of the Payment (after reduction) being subject to the Excise Tax or (y) the largest portion, up to and including the total, of
the Payment, whichever amount (i.e., the amount determined by clause (x) or by clause (y)), after taking into account all applicable
federal, state and local employment taxes, income taxes, and the Excise Tax (all computed at the highest applicable marginal rate),
results in your receipt, on an after-tax basis, of the greater economic benefit notwithstanding that all or some portion of the
Payment may be subject to the Excise Tax. If a reduction in a Payment is required pursuant to the preceding sentence and the Reduced
Amount is determined pursuant to clause (x) of the preceding sentence, the reduction shall occur in the manner (the “Reduction
Method”) that results in the greatest economic benefit for you. If more than one method of reduction will result
in the same economic benefit, the items so reduced will be reduced pro rata (the “Pro Rata Reduction Method”).

 

Notwithstanding the
foregoing, if the Reduction Method or the Pro Rata Reduction Method would result in any portion of the Payment being subject to
taxes pursuant to Section 409A that would not otherwise be subject to taxes pursuant to Section 409A, then the Reduction Method
and/or the Pro Rata Reduction Method, as the case may be, shall be modified so as to avoid the imposition of taxes pursuant to
Section 409A as follows: (A) as a first priority, the modification shall preserve to the greatest extent possible, the greatest
economic benefit for you as determined on an after-tax basis; (B) as a second priority, Payments that are contingent on future
events (e.g., being terminated without Cause), shall be reduced (or eliminated) before Payments that are not contingent on future
events; and (C) as a third priority, Payments that are “deferred compensation” within the meaning of Section 409A shall
be reduced (or eliminated) before Payments that are not deferred compensation within the meaning of Section 409A.

 

Unless you and the
Company agree on an alternative accounting firm, the accounting firm engaged by the Company for general tax compliance purposes
as of the day prior to the effective date of the change of control transaction triggering the Payment shall perform the foregoing
calculations. If the accounting firm so engaged by the Company is serving as accountant or auditor for the individual, entity or
group effecting the change of control transaction, the Company shall appoint a nationally recognized accounting firm to make the
determinations required hereunder. The Company shall bear all expenses with respect to the determinations by such accounting firm
required to be made hereunder. The Company shall use commercially reasonable efforts to cause the accounting firm engaged to make
the determinations hereunder to provide its calculations, together with detailed supporting documentation, to you and the Company
within fifteen (15) calendar days after the date on which your right to a 280G Payment becomes reasonably likely to occur (if requested
at that time by you or the Company) or such other time as requested by you or the Company.

 

If you receive a Payment
for which the Reduced Amount was determined pursuant to clause (x) of the first paragraph of this Section 10(b) and the Internal
Revenue Service determines thereafter that some portion of the Payment is subject to the Excise Tax, you shall promptly return
to the Company a sufficient amount of the Payment (after reduction pursuant to clause (x) of the first paragraph of this this Section
10(b) so that no portion of the remaining Payment is subject to the Excise Tax. For the avoidance of doubt, if the Reduced Amount
was determined pursuant to clause (y) in the first paragraph of this this Section 10(b), you shall have no obligation to return
any portion of the Payment pursuant to the preceding sentence.

 

    	 

    	 Page 5 of 8	 

    

 

11.              
Other. As a condition of employment, you must read, sign and comply with the Company’s Proprietary Information
and Invention Assignment Agreement (“PIIA”), which (among other provisions) prohibits any unauthorized
use or disclosure of Company proprietary, confidential or trade secret information. As required by law, this offer is subject to
satisfactory proof of your identity and right to work in the United States. Further, if requested by the Company, this offer is
contingent upon your successful completion of a background check to the satisfaction of the Company. If the Company desires that
you complete a background check, you will be required to give your consent for the Company, through an outside firm, to complete
a criminal background check and verification of information provided on your employment application.

 

12.              
Entire Agreement. Please let us know of your decision to join the Company by signing a copy of this Agreement and returning
it to us not later than June 1, 2017. This Agreement, together with your PIIA, sets forth our entire agreement and understanding
regarding the terms of your employment with the Company and supersedes any prior representations or agreements, whether written
or oral. This Agreement may not be modified in any way except in a writing signed by the Chairman of the Board upon due authorization
by the Board or its compensation committee and you. It shall be governed by California law, without regard to principles of conflicts
of laws.

  

	Sincerely,	 
	 	 
	/s/ Jeremy Curnock Cook	 
	 	 
	Jeremy Curnock Cook	 
	Chairman of the Board of Directors	 
	 	 
	 	 
	ACCEPTED AND AGREED:	 
	 	 
	 	 
	/s/ Paul C. Grint, M.D.	 
	Paul C. Grint, M.D.	 
	 	 
	1st June 2017	 
	Date	 

 

 

    	 

    	 Page 6 of 8	 

    

 

Exhibit
A

 

SEPARATION AGREEMENT AND RELEASE

 

 

I enter into this Separation
Agreement and Release (the “Release”) pursuant to Section 8 of the Offer Letter Agreement between AmpliPhi
Biosciences Corporation (the “Employer”), and me dated June 1, 2017 (the “Agreement”).
I acknowledge that my timely execution and return and my non-revocation of this Release are conditions to the payments and benefits
pursuant to Section 8 of the Agreement. I therefore agree to the following terms:

 

1.                 
Release of Claims. I voluntarily release and forever discharge the Employer, its affiliated and related entities,
its and their respective predecessors, successors and assigns, its and their respective employee benefit plans and fiduciaries
of such plans, and the current and former officers, directors, stockholders, members, employees, attorneys, accountants and agents
of each of the foregoing in their official and personal capacities (collectively referred to as the “Releasees”)
generally from all claims, demands, debts, damages and liabilities of every name and nature, known or unknown (“Claims”)
that, as of the date when I sign this Release, I have, ever had, now claim to have or ever claimed to have had against any or all
of the Releasees. This release includes, without limitation, all Claims:

 

		·	relating to my employment by the Employer and/or any affiliate of the Employer and the termination of my employment;

		·	of wrongful discharge;

		·	of breach of contract;

		·	of retaliation or discrimination under federal, state or local law (including, without limitation, Claims of age discrimination
or retaliation under the Age Discrimination in Employment Act, Claims of disability discrimination or retaliation under the Americans
with Disabilities Act, Claims of discrimination or retaliation under Title VII of the Civil Rights Act of 1964, Claims of any form
of discrimination or retaliation that is prohibited by the California Fair Employment and Housing Act;

		·	under any other federal or state statute;

		·	of defamation or other torts;

		·	of violation of public policy;

		·	for wages, bonuses, incentive compensation, stock, stock options, vacation pay or any other compensation or benefits (except
for such wages, bonuses, incentive compensation, stock, stock options, vacation pay or other compensation or benefits otherwise
due to me under the Agreement); and

		·	for damages or other remedies of any sort, including, without limitation, compensatory damages, punitive damages, injunctive
relief and attorney’s fees;

 

I agree that the release
set forth in this section shall be and remain in effect in all respects as a complete general release as to the matters released.
This release does not extend to any obligations incurred under this Release, under any ongoing Company benefit plans or for indemnification
under any indemnification agreement, the Company’s Bylaws or applicable law. This release does not release claims that cannot
be released as a matter of law, including, but not limited to, my right to file a charge with or participate in a charge by the
Equal Employment Opportunity Commission, or any other local, state, or federal administrative body or government agency that is
authorized to enforce or administer laws related to employment, against the Company (with the understanding that any such filing
or participation does not give me the right to recover any monetary damages against the Company; my release of claims herein bars
me from recovering such monetary relief from the Company).

 

    	 

    	 Page 7 of 8	 

    

 

I agree that I shall
not seek or accept damages of any nature, other equitable or legal remedies for my own benefit, attorney’s fees, or costs
from any of the Releasees with respect to any Claim released by this Release. I represent that I have not assigned to any third
party and I have not filed with any agency or court any Claim released by this Release.

 

Nothing in this Agreement
prevents me from filing a charge or complaint with the Equal Employment Opportunity Commission, the National Labor Relations Board,
the Occupational Safety and Health Administration, the Securities and Exchange Commission or any other federal, state or local
governmental agency or commission (collectively, the “Government Agencies”). I understand this Agreement
does not limit my ability to communicate with any Government Agencies or otherwise participate in any investigation or proceeding
that may be conducted by any Government Agency, including providing documents or other information, without notice to the Company. 
While this Agreement does not limit my right to receive an award for information provided to the Securities and Exchange Commission,
I understand and agree that, to the maximum extent permitted by law, I am otherwise waiving any and all rights I may have to individual
relief based on any claims that I have released and any rights I have waived by signing this Agreement.

 

2.                 
Ongoing Obligations. I reaffirm my ongoing obligations under the Agreement, including without limitation my obligations
under Section 11 with respect to the Proprietary Information and Invention Assignment Agreement.

 

3.                 
No Assignment. I represent that I have not assigned to any other person or entity any Claims against any Releasee.

 

4.                 
Right to Consider and Revoke Release. I acknowledge that I have been given the opportunity to consider this Release
for a period of twenty-one (21) days from the date when it is tendered to me. In the event that I executed this Release within
less than twenty-one (21) days, I acknowledge that such decision was entirely voluntary and that I had the opportunity to consider
this Release until the end of the twenty-one (21) day period. To accept this Release, I shall deliver a signed Release to
the Employer’s General Counsel within such twenty-one (21) day period; provided that I acknowledge that the Employer
may change the designated recipient by notice. For a period of seven (7) days from the date when I execute this Release (the
“Revocation Period”), I shall retain the right to revoke this Release by written notice that is
received by the Employer’s General Counsel or other Employer-designated recipient on or before the last day of the Revocation
Period. This Release shall take effect only if it is executed within the twenty-one (21) day period as set forth above and
if it is not revoked pursuant to the preceding sentence. If those conditions are satisfied, this Release shall become effective
and enforceable on the date immediately following the last day of the Revocation Period (the “Effective Date”).

 

    	 

    	 Page 8 of 8	 

    

 

 

5.                 
California Civil Code Section 1542. I acknowledge that I have been advised to consult with legal counsel and am familiar
with the provisions of California Civil Code Section 1542, a statute that otherwise prohibits the release of unknown claims,
which provides as follows:

 

A GENERAL RELEASE DOES NOT EXTEND
TO CLAIMS WHICH THE CREDITOR DOES NOT KNOW OR SUSPECT TO EXIST IN HIS OR HER FAVOR AT THE TIME OF EXECUTING THE RELEASE, WHICH
IF KNOWN BY HIM OR HER MUST HAVE MATERIALLY AFFECTED HIS OR HER SETTLEMENT WITH THE DEBTOR.

 

I, being aware of said code section, agree to expressly waive
any rights I may have thereunder, as well as under any other statute or common law principles of similar effect.

 

6.                 
Other Terms.

 

(a)              
Legal Representation; Review of Release. I acknowledge that I have been advised to discuss all aspects of this Release
with my attorney, that I have carefully read and fully understand all of the provisions of this Release and that I am voluntarily
entering into this Release.

 

(b)              
Binding Nature of Release. This Release shall be binding upon me and upon my heirs, administrators, representatives
and executors.

 

(c)              
Amendment. This Release may be amended only upon a written agreement executed by the Employer and me.

 

(d)              
Severability. In the event that at any future time it is determined by an arbitrator or court of competent jurisdiction
that any covenant, clause, provision or term of this Release is illegal, invalid or unenforceable, the remaining provisions and
terms of this Release shall not be affected thereby and the illegal, invalid or unenforceable term or provision shall be severed
from the remainder of this Release. In the event of such severance, the remaining covenants shall be binding and enforceable.

 

(e)              
Governing Law and Interpretation. This Release shall be deemed to be made and entered into in the State of California,
and shall in all respects be interpreted, enforced and governed under the laws of the State of California, without giving effect
to the conflict of laws principles of such State. The language of all parts of this Release shall in all cases be construed as
a whole, according to its fair meaning, and not strictly for or against either the Employer or me.

 

(f)               
Entire Agreement; Absence of Reliance. I acknowledge that I am not relying on any promises or representations by
the Employer or any of its agents, representatives or attorneys regarding any subject matter addressed in this Release.

 

So agreed.

 

		 	 	 
	Paul C. Grint, M.D.	 	Date

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