Document:

Seattle Genetics, Inc. Amended and Restated 2007 Equity Incentive Plan

 Exhibit 10.1 

SEATTLE GENETICS, INC. 

AMENDED AND RESTATED 

2007 EQUITY INCENTIVE PLAN 

(amended and restated by the Board August 5, 2009) 

(amended and restated by the Board March 11, 2010) 

(approved by the Company’s stockholders May 21, 2010) 

1. Purposes of the Plan.

The purpose of this Plan is to encourage ownership in Seattle Genetics, Inc., a Delaware corporation (the “Company”), by
key personnel whose long-term employment or other service relationship with the Company is considered essential to the Company’s continued progress and, thereby, encourage recipients to act in the stockholders’ interest and share in the
Company’s success. 
 2. Definitions.

As used herein, the following definitions shall apply: 

(a) “Administrator” means the Board, any Committees or such delegates as shall be
administering the Plan in accordance with Section 4 of the Plan. 

(b) “Affiliate” means any entity that is directly or indirectly controlled by the
Company or any entity in which the Company has a significant ownership interest as determined by the Administrator. 

(c) “Applicable Laws” means the requirements relating to the administration of stock
option and stock award plans under U.S. federal and state laws, the Code, any stock exchange or quotation system on which the Company has listed or submitted for quotation the Common Stock to the extent provided under the terms of the Company’s
agreement with such exchange or quotation system and, with respect to Awards subject to the laws of any foreign jurisdiction where Awards are, or will be, granted under the Plan, the laws of such jurisdiction. 

(d) “Award” means a Stock Award or Option granted in accordance with the terms of the
Plan. 
 (e) “Awardee” means an Employee, Consultant or Director of the Company
or any Affiliate who has been granted an Award under the Plan. 
 (f) “Award
Agreement” means a Stock Award Agreement and/or Option Agreement, which may be in written or electronic format, in such form and with such terms and conditions as may be specified by the Administrator, evidencing the terms and
conditions of an individual Award. Each Award Agreement is subject to the terms and conditions of the Plan. 

 (g) “Board” means the Board of Directors
of the Company. 
 (h) “Cause” means (i) an action or omission of Awardee which
constitutes a willful and intentional material breach of any written agreement or covenant with the Company, including without limitation, Awardee’s theft or other misappropriation of the Company’s proprietary information;
(ii) Awardee’s commitment of fraud, embezzlement, misappropriation of funds or breach of trust in connection with Awardee’s employment; or (iii) Awardee’s conviction of any crime which involves dishonesty or a breach of
trust, or gross negligence in connection with the performance of the Awardee’s duties. The determination as to whether an Awardee is being terminated for Cause shall be made in good faith by the Company and shall be final and binding on the
Awardee. The foregoing definition does not in any way limit the Company’s ability to terminate an Awardee’s employment or consulting relationship at any time as provided in Section 16 below, and the term “Company” will be
interpreted to include any Affiliate or successor thereto, if appropriate. 
 (i) “Change in
Control” means any of the following, unless the Administrator provides otherwise: 
 i. an
acquisition of the Company by another entity by means of any transaction or series of related transactions (including, without limitation, any reorganization, merger or consolidation but excluding any merger effected exclusively for the purpose of
changing the domicile of the Company); 
 ii. a sale of all or substantially all of the assets of the Company,
so long as in either i. or ii. above, the Company’s stockholders of record immediately prior to such transaction will, immediately after such transaction, hold less than fifty percent (50%) of the voting power of the surviving or acquiring
entity; or 
 iii. any other event specified by the Board or a Committee, regardless of whether at the time an
Award is granted or thereafter; provided, however, that no Change in Control (or any analogous term) shall be deemed to occur upon announcement or commencement of a tender offer or upon a “potential” takeover or upon shareholder approval
of a merger or other transaction, in each case without a requirement that the Change in Control actually occur. 

(j) “Code” means the United States Internal Revenue Code of 1986, as amended.

 (k) “Committee” means the compensation committee of the Board or a committee
of Directors appointed by the Board in accordance with Section 4 of the Plan. 

(l) “Common Stock” means the common stock of the Company. 

(m) “Company” means Seattle Genetics, Inc., a Delaware corporation, or its successor.

  

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 (n) “Constructive Termination” means
(A) there is a material reduction or change in job duties, responsibilities and requirements inconsistent with Awardee’s position with the Company and prior duties, responsibilities and requirements, provided that neither a mere change in
title alone nor reassignment to a position that is substantially similar to the position held prior to the change in terms of job duties, responsibilities or requirements shall constitute a material reduction in job responsibilities; or
(B) there is a reduction in Awardee’s then-current base salary by at least twenty percent (20%), provided that an across-the-board reduction in the salary level of all other employees by the same percentage amount as part of a general
salary level reduction shall not constitute such a salary reduction; or (C) Awardee refuses to relocate to a facility or location more than fifty (50) miles from the Company’s current location. 

(o) “Consultant” means any person engaged by the Company or any Affiliate to render services to such
entity as an advisor or consultant.
 (p) “Conversion Award” has the meaning set forth in
Section 4(b)(xi) of the Plan. 
 (q) “Director” means a member of the
Board. 
 (r) “Employee” means a regular, active employee of the Company
or any Affiliate, including an Officer and/or Inside Director. Within the limitations of Applicable Law, the Administrator shall have the discretion to determine the effect upon an Award and upon an individual’s status as an Employee in the
case of (i) any individual who is classified by the Company or its Affiliate as leased from or otherwise employed by a third party or as intermittent or temporary, even if any such classification is changed retroactively as a result of an
audit, litigation or otherwise, (ii) any leave of absence approved by the Company or an Affiliate, (iii) any transfer between locations of employment with the Company or an Affiliate or between the Company and any Affiliate or between any
Affiliates, (iv) any change in the Awardee’s status from an Employee to a Consultant or Director, and (v) at the request of the Company or an Affiliate an Employee becomes employed by any partnership, joint venture or corporation not
meeting the requirements of an Affiliate in which the Company or an Affiliate is a party. 

(s) “Exchange Act” means the Securities Exchange Act of 1934, as amended. 

(t) “Fair Market Value” of a Share on any given date means, unless otherwise required by
Applicable Law, the fair market value of such Share as determined in good faith by the Administrator either through application of any reasonable valuation method or, in the absence of any method established under law, in practice or otherwise to be
reasonable, then pursuant to the Administrator’s good faith conclusion that its valuation determination is reasonable; provided that, to the extent possible, such value shall be determined with reference to the closing price of the
Company’s Common Stock as quoted on the applicable date on Nasdaq or the exchange or market with the greatest volume of trading in the Common Stock as of the applicable date, or if the Shares were not trading on such date, then the closing bid
on the applicable date. The Administrator may make a good faith determination that it is reasonable to use one valuation method 

 

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with respect one type of transaction arising under the Plan and a different valuation method with respect to another type of Plan transaction, provided that in each case the Administrator
concludes that application of the particular method results in the most accurate measure of fair market value with respect thereto. 

(u) “Grant Date” means, for all purposes, the date on which the Administrator makes the
determination granting an Award, or such other date as is determined by the Administrator, provided that in the case of any Incentive Stock Option, the grant date shall be the later of the date on which the Administrator makes the determination
granting such Incentive Stock Option or the date of commencement of the Awardee’s employment relationship with the Company. 

(v) “Incentive Stock Option” means an Option intended to qualify as an incentive stock
option within the meaning of Section 422 of the Code and the regulations promulgated thereunder. 

(w) “Inside Director” means a Director who is an Employee. 

(x) “Nasdaq” means the Nasdaq Global Market or its successor.

(y) “Nonstatutory Stock Option” means an Option not intended to qualify as an
Incentive Stock Option. 
 (z) “Officer” means a person who is an officer of
the Company within the meaning of Section 16 of the Exchange Act and the rules and regulations promulgated thereunder. 

(aa) “Option” means a right granted under Section 8 to purchase a number of Shares
at such exercise price, at such times, and on such other terms and conditions as are specified in the agreement or other documents evidencing the Option (the “Option Agreement”). Both Options intended to qualify as Incentive Stock
Options and Nonstatutory Stock Options may be granted under the Plan. 
 (bb) “Outside
Director” means a Director who is not an Employee. 
 (cc) “Participant” means the
Awardee or any person (including any estate) to whom an Award has been assigned or transferred as permitted hereunder. 

(dd) “Plan” means this Seattle Genetics, Inc. Amended and Restated 2007 Equity Incentive
Plan. 
 (ee) “Qualifying Performance Criteria” shall have the meaning set
forth in Section 12(b) of the Plan. 
 (ff) “Share” means a share of the
Common Stock, as adjusted in accordance with Section 13 of the Plan. 
  

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 (gg) “Stock Appreciation Right” means a right to
receive cash and/or shares of Common Stock based on a change in the Fair Market Value of a specific number of shares of Common Stock between the Grant Date and the exercise date granted under Section 11.

(hh) “Stock Award” means an award or issuance of Shares, Stock Units, Stock Appreciation
Rights or other similar awards made under Section 11 of the Plan, the grant, issuance, retention, vesting, settlement and/or transferability of which is subject during specified periods of time to such conditions (including continued employment
or performance conditions) and terms as are expressed in the agreement or other documents evidencing the Award (the “Stock Award Agreement”). 

(ii) “Stock Unit” means a bookkeeping entry representing an amount equivalent to the
Fair Market Value of one Share (or a fraction or multiple of such value), payable in cash, property or Shares. Stock Units represent an unfunded and unsecured obligation of the Company, except as otherwise provided for by the Administrator.

 (jj) “Subsidiary” means any company (other than the Company) in an unbroken
chain of companies beginning with the Company, provided each company in the unbroken chain (other than the Company) owns, at the time of determination, stock possessing 50% or more of the total combined voting power of all classes of stock in one of
the other companies in such chain. 
 (kk) “Termination of Employment” shall
mean ceasing to be an Employee, Consultant or Director, as determined in the sole discretion of the Administrator. However, for Incentive Stock Option purposes, Termination of Employment will occur when the Awardee ceases to be an employee (as
determined in accordance with Section 3401(c) of the Code and the regulations promulgated thereunder) of the Company or one of its Subsidiaries. The Administrator shall determine whether any corporate transaction, such as a sale or spin-off of
a division or business unit, or a joint venture, shall be deemed to result in a Termination of Employment. 

(ll) “Total and Permanent Disability” shall have the meaning set forth in
Section 22(e)(3) of the Code. 
 3. Stock Subject to the Plan.

(a) Aggregate Limits. Subject to the provisions of Section 13 of the Plan, the maximum aggregate number
of Shares that may be sold or issued pursuant to Awards granted under the Plan is 12,500,000 Shares. 
 Shares subject to Awards
granted under the Plan that are cancelled, expire or are forfeited (including without limitation, any such Shares having been issued under the Award to the Participant) shall be available for re-grant under the Plan. If an Awardee pays the exercise
or purchase price of an Award granted under the Plan through the tender of Shares, or if Shares are tendered or withheld to satisfy any Company withholding 

 

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obligations, the number of Shares so tendered or withheld shall become available for re-issuance thereafter under the Plan. The Shares subject to the Plan may be either Shares reacquired by the
Company, including Shares purchased in the open market, or authorized but unissued Shares. 
 (b) Code
Section 162(m) Share Limits. Subject to the provisions of Section 13 of the Plan, the aggregate number of Shares subject to Awards granted under this Plan during any calendar year to any one Awardee shall not exceed 1,000,000.
Notwithstanding anything to the contrary in the Plan, the limitation set forth in this Section 3(b) shall be subject to adjustment under Section 13(a) of the Plan only to the extent that such adjustment will not affect the status of any
Award intended to qualify as “performance based compensation” under Code Section 162(m). 

4. Administration of the Plan.

(a) Procedure.

i. Multiple Administrative Bodies. The Plan shall be administered by the Board, a Committee and/or their
delegates. 
 ii. Section 162. To the extent that the Administrator determines it to be
desirable to qualify Awards granted hereunder as “performance-based compensation” within the meaning of Section 162(m) of the Code, Awards to “covered employees” within the meaning of Section 162(m) of the Code or
Employees that the Committee determines may be “covered employees” in the future shall be made by a Committee of two or more “outside directors” within the meaning of Section 162(m) of the Code. 

iii. Rule 16b-3. To the extent desirable to qualify transactions hereunder as exempt under
Rule 16b-3 promulgated under the Exchange Act (“Rule 16b-3”), Awards to Officers and Directors shall be made by the entire Board or a Committee of two or more “non-employee directors” within the meaning of
Rule 16b-3. 
 iv. Other Administration. The Board or a Committee may delegate to an
authorized officer or officers of the Company the power to approve Awards to persons eligible to receive Awards under the Plan who are not (A) subject to Section 16 of the Exchange Act or (B) at the time of such approval,
“covered employees” under Section 162(m) of the Code or (C) any other executive officer. 

v. Delegation of Authority for the Day-to-Day Administration of the Plan. Except to the extent
prohibited by Applicable Law, the Administrator may delegate to one or more individuals the day-to-day administration of the Plan and any of the functions assigned to it in this Plan. Such delegation may be revoked at any time. 

 

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 vi. Nasdaq. The Plan will be administered in a manner that complies
with any applicable Nasdaq or stock exchange listing requirements. 
 (b) Powers of the
Administrator. Subject to the provisions of the Plan and, in the case of a Committee or delegates acting as the Administrator, subject to the specific duties delegated to such Committee or delegates, the Administrator shall have the
authority, in its discretion: 
 i. to select the Employees, Consultants and Directors of the Company or
its Affiliates to whom Awards are to be granted hereunder; 
 ii. to determine the number of shares of
Common Stock or amount of cash to be covered by each Award granted hereunder; 
 iii. to determine the type
of Award to be granted to the selected Employees, Consultants and Directors; 
 iii. to approve forms of
Award Agreements for use under the Plan; 
 iv. to determine the terms and conditions, not inconsistent
with the terms of the Plan, of any Award granted hereunder. Such terms and conditions include, but are not limited to, the exercise and/or purchase price (if applicable), the time or times when an Award may be exercised (which may or may not be
based on performance criteria), the vesting schedule, any vesting and/or exercisability acceleration or waiver of forfeiture restrictions, the acceptable forms of consideration, the term, and any restriction or limitation regarding any Award or the
Shares relating thereto, based in each case on such factors as the Administrator, in its sole discretion, shall determine and may be established at the time an Award is granted or thereafter; 

v. to determine whether and under what circumstances an Option may be settled in cash under Section 8(h) instead of
Common Stock; 
 vi. to correct administrative errors; 

vii. to construe and interpret the terms of the Plan (including sub-plans and Plan addenda) and Awards granted
pursuant to the Plan; 
 viii. to adopt rules and procedures relating to the operation and administration
of the Plan to accommodate the specific requirements of local laws and procedures. Without limiting the generality of the foregoing, the Administrator is specifically authorized (A) to adopt the rules and procedures regarding the conversion of
local currency, withholding procedures and handling of stock certificates which vary with local requirements and (B) to adopt sub-plans and Plan addenda as the Administrator deems desirable, to accommodate foreign laws, regulations and
practice; 
  

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 ix. to prescribe, amend and rescind rules and regulations relating to
the Plan, including rules and regulations relating to sub-plans and Plan addenda; 
 x. to modify or amend
each Award, including, but not limited to, the acceleration of vesting and/or exercisability, provided, however, that any such amendment is subject to Section 14 of the Plan and except as set forth in that Section, may not impair any
outstanding Award unless agreed to in writing by the Participant; 
 xi. to allow Participants to satisfy
withholding tax amounts by electing to have the Company withhold from the Shares to be issued upon exercise of an Option or vesting of a Stock Award that number of Shares having a Fair Market Value equal to the amount required to be withheld. The
Fair Market Value of the Shares to be withheld shall be determined in such manner and on such date that the Administrator shall determine or, in the absence of provision otherwise, on the date that the amount of tax to be withheld is to be
determined. All elections by a Participant to have Shares withheld for this purpose shall be made in such form and under such conditions as the Administrator may provide; 

xii. to authorize conversion or substitution under the Plan of any or all stock options, stock appreciation rights
or other stock awards held by service providers of an entity acquired by the Company (the “Conversion Awards”). Any conversion or substitution shall be effective as of the close of the merger, acquisition or other transaction. The
Conversion Awards may be Nonstatutory Stock Options or Incentive Stock Options, as determined by the Administrator, with respect to options granted by the acquired entity; provided, however, that with respect to the conversion of stock appreciation
rights in the acquired entity, the Conversion Awards shall be Nonstatutory Stock Options. Unless otherwise determined by the Administrator at the time of conversion or substitution, all Conversion Awards shall have the same terms and conditions as
Awards generally granted by the Company under the Plan; 
 xiii. to authorize any person to execute on
behalf of the Company any instrument required to effect the grant of an Award previously granted by the Administrator; 

xiv. to impose such restrictions, conditions or limitations as it determines appropriate as to the timing and manner
of any resales by a Participant or other subsequent transfers by the Participant of any Shares issued as a result of or under an Award, including without limitation, (A) restrictions under an insider trading policy or under any other Company
policy relating to Company stock and stock ownership and (B) restrictions as to the use of a specified brokerage firm for such resales or other transfers; 
  

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 xv. to provide, either at the time an Award is granted or by
subsequent action, that an Award shall contain as a term thereof, a right, either in tandem with the other rights under the Award or as an alternative thereto, of the Participant to receive, without payment to the Company, a number of Shares, cash
or a combination thereof, the amount of which is determined by reference to the value of the Award; and 

xvi. to make all other determinations deemed necessary or advisable for administering the Plan and any Award granted
hereunder. 
 (c) Effect of Administrator’s Decision. All decisions, determinations and
interpretations by the Administrator regarding the Plan, any rules and regulations under the Plan and the terms and conditions of any Award granted hereunder, shall be final and binding on all Participants and on all other persons. The Administrator
shall consider such factors as it deems relevant, in its sole and absolute discretion, to making such decisions, determinations and interpretations including, without limitation, the recommendations or advice of any officer or other employee of the
Company and such attorneys, consultants and accountants as it may select. 
 5. Eligibility.

Awards may be granted to Employees, Consultants and Directors of the Company or any of its Affiliates; provided that Incentive Stock
Options may be granted only to Employees of the Company or of a Subsidiary of the Company. 
 6. Term of
Plan.
 The Plan shall become effective on December 23, 2007 contingent upon approval of the stockholders of the
Company. It shall continue in effect for a term of ten (10) years from the later of the date the stockholders of the Company approve the Plan or the date any amendment to add shares to the Plan is approved by stockholders of the Company, unless
terminated earlier under Section 14 of the Plan. 
 7. Term of Award.

The term of each Award shall be determined by the Administrator and stated in the Award Agreement. In the case of an Option, the term
shall be ten (10) years from the Grant Date or such shorter term as may be provided in the Award Agreement; provided that an Incentive Stock Option granted to an Employee who on the Grant Date owns stock representing more than ten percent
(10%) of the voting power of all classes of stock of the Company or any Subsidiary shall have a term of no more than five (5) years from the Grant Date. 

8. Options.

The Administrator may grant an Option or provide for the grant of an Option, either from time to time in the discretion of the
Administrator or automatically upon the occurrence of specified events, including, without limitation, the achievement of performance goals, the satisfaction of an event or condition within the control of the Awardee or within the control of others.

  

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 (a) Option Agreement. Each Option Agreement shall contain
provisions regarding (i) the number of Shares that may be issued upon exercise of the Option, (ii) the type of Option, (iii) the exercise price of the Shares and the means of payment for the Shares, (iv) the term of the Option,
(v) such terms and conditions on the vesting and/or exercisability of an Option as may be determined from time to time by the Administrator, (vi) restrictions on the transfer of the Option or the Shares issued upon exercise of the Option
and forfeiture provisions on either and (vii) such further terms and conditions, in each case not inconsistent with this Plan as may be determined from time to time by the Administrator. 

(b) Exercise Price. The per share exercise price for the Shares to be issued pursuant to exercise of an
Option shall be determined by the Administrator, subject to the following: 
 i. In the case of an
Incentive Stock Option, the per Share exercise price shall be no less than one hundred percent (100%) of the Fair Market Value per Share on the Grant Date; provided however, that in the case of an Incentive Stock Option granted to an Employee
who on the Grant Date owns stock representing more than ten percent (10%) of the voting power of all classes of stock of the Company or any Subsidiary, the per Share exercise price shall be no less than one hundred ten percent (110%) of
the Fair Market Value per Share on the Grant Date. 
 ii. In the case of a Nonstatutory Stock Option, the
per Share exercise price shall be no less than one hundred percent (100%) of the Fair Market Value per Share on the Grant Date. 

iii. Notwithstanding the foregoing, at the Administrator’s discretion, Conversion Awards may be granted in
substitution and/or conversion of options of an acquired entity, with a per Share exercise price of less than 100% of the Fair Market Value per Share on the date of such substitution and/or conversion. 

(c) No Option Repricings. Other than in connection with a change in the Company’s capitalization (as described
in Section 14(a) of the Plan), the exercise price of an Option may not be reduced without stockholder approval. 

(d) Vesting Period and Exercise Dates. Options granted under this Plan shall vest and/or be exercisable
at such time and in such installments during the period prior to the expiration of the Option’s term as determined by the Administrator. The Administrator shall have the right to make the timing of the ability to exercise any Option granted
under this Plan subject to continued employment, the passage of time and/or such performance requirements as deemed appropriate by the Administrator. At any time after the grant of an Option, the Administrator may reduce or eliminate any
restrictions surrounding any Participant’s right to exercise all or part of the Option. 
  

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 (e) Form of Consideration. The Participant may pay the
exercise price of an Option using any of the following forms of consideration, unless the Administrator determines not to permit such form of consideration at any time including at the time of exercise: 

i. cash; 

ii. check or wire transfer (denominated in U.S. Dollars); 

iii. subject to the Company’s discretion to refuse for any reason and at any time to accept such consideration
and subject to any conditions or limitations established by the Administrator, other Shares held by the Participant which have a Fair Market Value on the date of surrender equal to the aggregate exercise price of the Shares as to which said
Option shall be exercised; 
 iv. consideration received by the Company under a broker-assisted sale and
remittance program acceptable to the Administrator; 
 v. cashless “net exercise” arrangement
pursuant to which the Company will reduce the number of Shares issued upon exercise by the largest whole number of Shares having an aggregate Fair Market Value that does not exceed the aggregate exercise price; provided that the Company shall accept
a cash or other payment from the Participant to the extent of any remaining balance of the exercise price not satisfied by such reduction in the number of whole Shares to be issued; and also provided that Shares will no longer be outstanding under
an Option and will not be exercisable thereafter to the extent that (A) Shares are withheld to pay the exercise price pursuant to a “net exercise,” and (B) the remaining number of whole Shares are delivered to the Participant as
a result of such exercise; 
 vi. such other consideration and method of payment for the issuance of Shares
to the extent permitted by Applicable Laws; or 
 vii. any combination of the foregoing methods of payment.

 (f) Effect of Termination on Options 

i. Generally. Unless otherwise provided for by the Administrator, upon an Awardee’s Termination of
Employment other than as a result of circumstances described in Sections 8(f)(ii) and (iii) below, any outstanding Option granted to such Awardee, whether vested or unvested, to the extent not theretofore exercised, shall terminate immediately
upon the Awardee’s Termination of Employment; provided, however, that the Administrator may in the Option Agreement specify a 

 

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period of time (but not beyond the expiration date of the Option) following Termination of Employment during which the Awardee may exercise the Option as to Shares that were vested and
exercisable as of the date of Termination of Employment. To the extent such a period following Termination of Employment is specified, the Option shall automatically terminate at the end of such period to the extent the Awardee has not exercised it
within such period. 
 ii. Disability of Awardee. Unless otherwise provided for by the
Administrator, upon an Awardee’s Termination of Employment as a result of the Awardee’s disability, including Total and Permanent Disability, all outstanding Options granted to such Awardee that were vested and exercisable as of the date
of the Awardee’s Termination of Employment may be exercised by the Awardee until (A) twelve (12) months following Awardee’s Termination of Employment as a result of Awardee’s disability, including Total and Permanent
Disability or (B) the expiration of the term of such Option. If the Participant does not exercise such Option within the time specified, the Option (to the extent not exercised) shall automatically terminate. 

iii. Death of Awardee. Unless otherwise provided for by the Administrator, upon an Awardee’s
Termination of Employment as a result of the Awardee’s death or in the event of the death of an Awardee within thirty (30) days following an Awardee’s Termination of Employment, all outstanding Options granted to such Awardee that
were vested and exercisable as of the date of the Awardee’s death, or if earlier the date of Termination of Employment, may be exercised until the earlier of (A) six (6) months following the Awardee’s death or (B) the
expiration of the term of such Option. If an Option is held by the Awardee when he or she dies, such Option may be exercised, to the extent the Option is vested and exercisable, by the beneficiary designated by the Awardee (as provided in
Section 15 of the Plan), the executor or administrator of the Awardee’s estate or, if none, by the person(s) entitled to exercise the Option under the Awardee’s will or the laws of descent or distribution; provided that the Company
need not accept exercise of an Option by such beneficiary, executor or administrator unless the Company has satisfactory evidence of such person’s authority to act as such. If the Option is not so exercised within the time specified, such
Option (to the extent not exercised) shall automatically terminate. 
 iv. Termination for
Cause. The Administrator has the authority to cause all outstanding Options held by an Awardee to terminate immediately in their entirety upon first notification to the Awardee of the Awardee’s Termination of Employment for Cause. If
an Awardee’s employment or consulting relationship with the Company is suspended pending an investigation of whether the Awardee shall be terminated for Cause, the Administrator has the authority to cause all the Awardee’s rights under all
outstanding Options to be suspended during the investigation period in which event the Awardee shall have no right to exercise any outstanding Options. 
  

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 v. Other Terminations of Employment. The Administrator may provide
in the applicable Option Agreement for different treatment of Options upon Termination of Employment of the Awardee than that specified above. 

vi. Extension of Exercise Period. The Administrator shall have full power and authority to extend the period of
time for which an Option is to remain exercisable following an Awardee’s Termination of Employment from the periods set forth in Sections 8(f)(ii) and (iii) above or in the Option Agreement to such greater time as the Board shall deem
appropriate, provided that in no event shall such Option be exercisable later than the date of expiration of the term of such Option as set forth in the Option Agreement. 

(g) Leave of Absence. The Administrator shall have the discretion to determine whether and to what extent the
vesting of Options shall be tolled during any unpaid leave of absence; provided, however, that in the absence of such determination, vesting of Options shall be tolled during any leave that is not a leave required to be provided to the Awardee under
Applicable Law. In the event of military leave, vesting shall toll during any unpaid portion of such leave, provided that, upon an Awardee’s returning from military leave (under conditions that would entitle him or her to protection upon such
return under the Uniform Services Employment and Reemployment Rights Act), he or she shall be given vesting credit with respect to Options to the same extent as would have applied had the Awardee continued to provide services to the Company
throughout the leave on the same terms as he or she was providing services immediately prior to such leave. 

(h) Buyout Provisions. The Administrator may at any time offer to buy out for a payment in cash or Shares, an
Option previously granted, based on such terms and conditions as the Administrator shall establish and communicate to the Awardee at the time that such offer is made. 

9. Incentive Stock Option Limitations/Terms.

(a) Eligibility. Only employees (as determined in accordance with Section 3401(c) of the Code and
the regulations promulgated thereunder) of the Company or any of its Subsidiaries may be granted Incentive Stock Options. 

(b) $100,000 Limitation. Notwithstanding the designation “Incentive Stock Option” in an Option
Agreement, if and to the extent that the aggregate Fair Market Value of the Shares with respect to which Incentive Stock Options are exercisable for the first time by the Awardee during any calendar year (under all plans of the Company and any of
its Subsidiaries) exceeds U.S. $100,000, such Options shall be treated as Nonstatutory Stock Options. For purposes of this Section 9(b), Incentive Stock Options shall be taken into account in the order in which they were granted. The Fair
Market Value of the Shares shall be determined as of the Grant Date. 
  

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 (c) Transferability. An Incentive Stock Option may not be
sold, pledged, assigned, hypothecated, transferred or disposed of in any manner by the Awardee otherwise than by will or the laws of descent and distribution, and, during the lifetime of such Awardee, may only be exercised by the Awardee. If the
terms of an Incentive Stock Option are amended to permit transferability, the Option will be treated for tax purposes as a Nonstatutory Stock Option. The designation of a beneficiary by an Awardee will not constitute a transfer. 

(d) Exercise Price. The per Share exercise price of an Incentive Stock Option shall be determined by the
Administrator in accordance with Section 8(b)(i) of the Plan. 
 (e) Other
Terms. Option Agreements evidencing Incentive Stock Options shall contain such other terms and conditions as may be necessary to qualify, to the extent determined desirable by the Administrator, with the applicable provisions of
Section 422 of the Code. 
 10. Exercise of Option.

(a) Procedure for Exercise.  

i. Any Option granted hereunder shall be exercisable according to the terms of the Plan and at such times and under
such conditions as determined by the Administrator and set forth in the respective Option Agreement. 

ii. An Option shall be deemed exercised when the Company receives (A) written or electronic notice of exercise
(in accordance with the Option Agreement) from the person entitled to exercise the Option; (B) full payment for the Shares with respect to which the related Option is exercised; and (C) payment of all applicable withholding taxes.

 iii. An Option may not be exercised for a fraction of a Share. 

(b) Rights as a Stockholder. The Company shall issue (or cause to be issued) such Shares as administratively
practicable after the Option is exercised. Shares issued upon exercise of an Option shall be issued in the name of the Participant or, if requested by the Participant, in the name of the Participant and his or her spouse. Unless provided otherwise
by the Administrator or pursuant to this Plan, until the Shares are issued (as evidenced by the appropriate entry on the books of the Company or of a duly authorized transfer agent of the Company), no right to vote or receive dividends or any other
rights as a stockholder shall exist with respect to the Shares subject to an Option, notwithstanding the exercise of the Option. 
  

 14 

 11. Stock Awards.

(a) Stock Award Agreement. Each Stock Award Agreement shall contain provisions regarding (i) the
number of Shares subject to such Stock Award or a formula for determining such number, (ii) the purchase price of the Shares, if any, and the means of payment for the Shares, (iii) the performance criteria (including Qualifying Performance
Criteria), if any, and level of achievement versus these criteria that shall determine the number of Shares granted, issued, retainable and/or vested, (iv) such terms and conditions on the grant, issuance, vesting, settlement and/or forfeiture
of the Shares as may be determined from time to time by the Administrator, (v) restrictions on the transferability of the Stock Award and (vi) such further terms and conditions in each case not inconsistent with this Plan as may be
determined from time to time by the Administrator; provided, however, that each Stock Award must have a minimum vesting period of one (1) year from the Grant Date. 

(b) Restrictions and Performance Criteria. The grant, issuance, retention, vesting and/or settlement of
each Stock Award or the Shares subject thereto may be subject to such performance criteria (including Qualifying Performance Criteria) and level of achievement versus these criteria as the Administrator shall determine, which criteria may be based
on financial performance, personal performance evaluations and/or completion of service by the Awardee. Unless otherwise permitted in compliance with the requirements of Code Section 162(m) with respect to an Award intended to comply as
“performance-based compensation” thereunder, the Committee shall establish the Qualifying Performance Criteria applicable to, and the formula for calculating the amount payable under, the Award no later than the earlier of (a) the
date ninety (90) days after the commencement of the applicable performance period, or (b) the date on which 25% of the performance period has elapsed, and in any event at a time when the achievement of the applicable Qualifying Performance
Criteria remains substantially uncertain. 
 (c) Forfeiture. Unless otherwise provided for by
the Administrator, upon the Awardee’s Termination of Employment, the Stock Award and the Shares subject thereto shall be forfeited, provided that to the extent that the Participant purchased or earned any Shares, the Company shall have a right
to repurchase the unvested Shares at such price and on such terms and conditions as the Administrator determines. 

(d) Rights as a Stockholder. Unless otherwise provided by the Administrator in the Award Agreement, the
Participant shall have the rights equivalent to those of a stockholder and shall be a stockholder only after Shares are issued (as evidenced by the appropriate entry on the books of the Company or of a duly authorized transfer agent of the Company)
to the Participant. Unless otherwise provided by the Administrator, a Participant holding Stock Units shall not be entitled to receive dividend payments or any credit therefore as if he or she was an actual stockholder. 

(e) Stock Appreciation Rights. 

i. General. Stock Appreciation Rights may be granted either alone, in addition to, or in tandem with other Awards
granted under the Plan. The Board may grant Stock Appreciation Rights to eligible Participants subject to terms and conditions not inconsistent with this Plan and determined by the Board. The specific terms and conditions applicable to the
Participant shall be provided for in the Stock Award Agreement. Stock Appreciation Rights shall be exercisable, in whole or in part, at such times as the Board shall specify in the Stock Award Agreement. 

 

 15 

 ii. Exercise of Stock Appreciation Right. Upon the exercise
of a Stock Appreciation Right, in whole or in part, the Participant shall be entitled to a payment in an amount equal to the excess of the Fair Market Value on the date of exercise of a fixed number of Shares covered by the exercised portion of the
Stock Appreciation Right, over the Fair Market Value on the Grant Date of the Shares covered by the exercised portion of the Stock Appreciation Right (or such other amount calculated with respect to Shares subject to the Award as the Board may
determine). The amount due to the Participant upon the exercise of a Stock Appreciation Right shall be paid in such form of consideration as determined by the Board and may be in cash, Shares or a combination thereof, over the period or periods
specified in the Stock Award Agreement. A Stock Award Agreement may place limits on the amount that may be paid over any specified period or periods upon the exercise of a Stock Appreciation Right, on an aggregate basis or as to any Participant. A
Stock Appreciation Right shall be considered exercised when the Company receives written notice of exercise in accordance with the terms of the Stock Award Agreement from the person entitled to exercise the Stock Appreciation Right. 

iii. Nonassignability of Stock Appreciation Rights. Except as determined by the Administrator, no Stock
Appreciation Right shall be assignable or otherwise transferable by the Participant except by will or by the laws of descent and distribution. 

12. Other Provisions Applicable to Awards.

(a) Non-Transferability of Awards. Unless determined otherwise by the Administrator, an Award may not be
sold, pledged, assigned, hypothecated, transferred, or disposed of in any manner other than by beneficiary designation, will or by the laws of descent or distribution. Subject to Section 9(c), the Administrator may in its discretion make an
Award transferable to an Awardee’s family member or any other person or entity as it deems appropriate. If the Administrator makes an Award transferable, either at the time of grant or thereafter, such Award shall contain such additional terms
and conditions as the Administrator deems appropriate, and any transferee shall be deemed to be bound by such terms upon acceptance of such transfer. 

(b) Qualifying Performance Criteria. For purposes of this Plan, the term “Qualifying Performance
Criteria” shall mean any one or more of the following performance criteria, either individually, alternatively or in any combination, applied to either the Company as a whole or to a business unit, Affiliate or business segment, either
individually, alternatively or in any combination, and measured either annually or cumulatively over a period of years, on an absolute basis or relative to a pre-established target, to previous years’ results or to a designated comparison
group, in each case as specified by the Administrator in the Award: (i) cash flow; (ii) earnings (including gross 
  

 16 

 
margin, earnings before interest and taxes, earnings before taxes, and net earnings); (iii) earnings per share; (iv) growth in earnings or earnings per share; (v) stock price;
(vi) return on equity or average stockholders’ equity; (vii) total stockholder return; (viii) return on capital; (ix) return on assets or net assets; (x) return on investment; (xi) revenue; (xii) income or net
income; (xiii) operating income or net operating income, in aggregate or per share; (xiv) operating profit or net operating profit; (xv) operating margin; (xvi) return on operating revenue; (xvii) market share;
(xviii) growth in stockholder value relative to the moving average of a peer group index; (xix) strategic plan development and implementation (including individual performance objectives that relate to achievement of the Company’s or
any business unit’s strategic plan); (xx) improvement in workforce diversity; (xxi) growth of revenue, operating income or net income; (xxii) approval by the U.S. Food and Drug Administration or other regulatory body of a product
candidate; and (xxiii) any other similar criteria. The Committee may appropriately adjust any evaluation of performance under a Qualifying Performance Criteria to exclude any of the following events that occurs during a performance period:
(A) asset write-downs; (B) litigation or claim judgments or settlements; (C) the effect of changes in tax law, accounting principles or other such laws or provisions affecting reported results; (D) accruals for reorganization and
restructuring programs and/or other nonrecurring charges; and (E) any gains or losses classified as “extraordinary” under generally accepted accounting principles or discontinued operations in the Company’s financial statements.

 (c) Certification. Prior to the payment of any compensation under an Award intended to
qualify as “performance-based compensation” under Section 162(m) of the Code, the Committee shall certify the extent to which any Qualifying Performance Criteria and any other material terms under such Award have been satisfied (other
than in cases where such relate solely to the increase in the value of the Common Stock). 

(d) Discretionary Adjustments Pursuant to Section 162(m). Notwithstanding satisfaction of any
completion of any Qualifying Performance Criteria, to the extent specified at the time of grant of an Award to “covered employees” within the meaning of Section 162(m) of the Code, the number of Shares, Options or other benefits
granted, issued, retainable and/or vested under an Award on account of satisfaction of such Qualifying Performance Criteria may be reduced by the Committee on the basis of such further considerations as the Committee in its sole discretion shall
determine. 
 (e) Compliance with Section 409A. Notwithstanding anything to the contrary
contained herein, to the extent that the Administrator determines that any Award granted under the Plan is subject to Code Section 409A and unless otherwise specified in the applicable Award Agreement, the Award Agreement evidencing such Award
shall incorporate the terms and conditions necessary for such Award to avoid the consequences described in Code Section 409A(a)(1), and to the maximum extent permitted under Applicable Law (and unless otherwise stated in the applicable Award
Agreement), the Plan and the Award Agreements shall be interpreted in a manner that results in their conforming to the requirements of Code Section 409A(a)(2), (3) and (4) and any Department of Treasury or Internal Revenue Service
regulations or other interpretive 
  

 17 

 
guidance issued under Section 409A (whenever issued, the “Guidance”). Notwithstanding anything to the contrary in this Plan (and unless the Award Agreement provides
otherwise, with specific reference to this sentence), to the extent that a Participant holding an Award that constitutes “deferred compensation” under Section 409A and the Guidance is a “specified employee” (also as defined
thereunder), no distribution or payment of any amount shall be made before a date that is six (6) months following the date of such Participant’s “separation from service” (as defined in Section 409A and the Guidance) or, if
earlier, the date of the Participant’s death. 
 (f) Deferral of Award Benefits. The
Administrator may in its discretion and upon such terms and conditions as it determines appropriate permit one or more Participants whom it selects to (a) defer compensation payable pursuant to the terms of an Award, or (b) defer
compensation arising outside the terms of this Plan pursuant to a program that provides for deferred payment in satisfaction of such other compensation amounts through the issuance of one or more Awards. Any such deferral arrangement shall be
evidenced by an Award Agreement in such form as the Administrator shall from time to time establish, and no such deferral arrangement shall be a valid and binding obligation unless evidenced by a fully executed Award Agreement, the form of which the
Administrator has approved, including through the Administrator’s establishing a written program (the “Program”) under this Plan to govern the form of Award Agreements participating in such Program. Any such Award Agreement or Program
shall specify the treatment of dividends or dividend equivalent rights (if any) that apply to Awards governed thereby, and shall further provide that any elections governing payment of amounts pursuant to such Program shall be in writing, shall be
delivered to the Company or its agent in a form and manner that complies with Code Section 409A and the Guidance, and shall specify the amount to be distributed in settlement of the deferral arrangement, as well as the time and form of such
distribution in a manner that complies with Code Section 409A and the Guidance. 
 13. Adjustments upon Changes in
Capitalization, Dissolution, Merger or Asset Sale.
 (a) Changes in Capitalization. Subject
to any required action by the stockholders of the Company, (i) the number and kind of Shares covered by each outstanding Award, (ii) the exercise or purchase (including repurchase) price per Share subject to each such outstanding Award and
(iii) each of the Share limitations set forth in Section 3 of the Plan, shall be proportionately adjusted for any increase or decrease in the number or kind of issued shares resulting from a stock split, reverse stock split, stock
dividend, spin-off, combination or reclassification of the Common Stock, or any other similar increase or decrease in the number of issued shares of Common Stock effected without receipt of consideration by the Company; provided, however, that
conversion of any convertible securities of the Company shall not be deemed to have been “effected without receipt of consideration.” Such adjustment shall be made by the Administrator, whose determination in that respect shall be final,
binding and conclusive. Except as expressly provided herein, no issuance by the Company of shares of stock of any class, or securities convertible into shares of stock of any class, shall affect, and no adjustment by reason thereof shall be made
with respect to, the number or price of shares of Common Stock subject to an Award. 
  

 18 

 (b) Dissolution or Liquidation. In the event of the
proposed dissolution or liquidation of the Company, the Administrator shall notify each Participant as soon as practicable prior to the effective date of such proposed transaction. To the extent an Award has not been previously exercised or the
Shares subject thereto issued to the Awardee and unless otherwise determined by the Administrator, an Award will terminate immediately prior to the consummation of the transaction. In addition, the Administrator may provide that any Company
repurchase option or forfeiture applicable to any Shares purchased upon exercise of an Option or covered by a Stock Award shall lapse as to all such Shares, provided the proposed liquidation or dissolution takes place at the time and in the matter
contemplated. 
 (c) Change in Control. In the event there is a Change in Control of the
Company, as determined by the Board or a Committee, the Board or Committee may, in its discretion, (i) provide for the assumption or substitution of, or adjustment (including to the number and type of Shares and exercise or purchase price
applicable) to, each outstanding Award; (ii) accelerate the vesting of Options and terminate any restrictions on Stock Awards and/or (iii) provide for termination of Awards as a result of the Change in Control on such terms and conditions
as it deems appropriate, including providing for the cancellation of Awards for a cash or other payment to the Participant. 

For purposes of this Section 13(c), an Award shall be considered assumed, without limitation, if, at the time of
issuance of the stock or other consideration upon a Change in Control, as the case may be, each holder of an Award would be entitled to receive upon exercise of the Award the same number and kind of shares of stock or the same amount of property,
cash or securities as such holder would have been entitled to receive upon the occurrence of the transaction if the holder had been, immediately prior to such transaction, the holder of the number of Shares covered by the Award at such time (after
giving effect to any adjustments in the number of Shares covered by the Award as provided for in Section 13(a)); provided that if such consideration received in the transaction is not solely common stock of the successor corporation, the
Administrator may, with the consent of the successor corporation, provide for the consideration to be received upon exercise of the Award to be solely common stock of the successor corporation equal to the Fair Market Value of the per Share
consideration received by holders of Common Stock in the transaction. 
 In the event of a Change in Control, and
if an Awardee’s Awards are not assumed by the successor corporation or its parent or subsidiary and such successor does not substitute equivalent options or awards for those outstanding under the Plan and the Awardee has not experienced a
Termination of Employment without Cause as of, or has experienced a Termination of Employment without Cause immediately prior to, the effective time of the Change in Control, then such Awards shall become fully vested and exercisable and/or payable
as applicable, and all forfeiture or repurchase restrictions on such Awards shall lapse immediately prior to the effective time of the Change in Control. 

 

 19 

 
Upon, or in anticipation of, such Change in Control, the Administrator may cause any and all Awards outstanding under the Plan to terminate at a specific time in the future and shall give each
Awardee the right to exercise such Awards during a period of time as the Administrator, in its sole and absolute discretion, shall determine. The Administrator shall have sole discretion to determine whether an Award has been assumed by the
successor corporation or its parent or subsidiary or whether such successor has substituted equivalent awards for those outstanding under the Plan in connection with a Change in Control subject to the preceding paragraph. 

In the event of a Change in Control, if outstanding Awards are assumed or equivalent awards are substituted by the
successor corporation or a parent or subsidiary of such successor corporation, and if at the time of, immediately prior to or within twelve (12) months after, the effective time of such Change in Control, an Awardee experiences a Termination of
Employment without Cause or as a result of a Constructive Termination, then, as of the date of Awardee’s Termination of Employment, the vesting and exercisability of any assumed Option, or any option substituted for an Option by the successor
corporation or a parent or subsidiary of such successor corporation, held by Awardee at the time of termination, and the lapse of any forfeiture or repurchase restrictions with respect to any assumed Stock Award, or any stock award substituted for a
Stock Award by the successor corporation or a parent or subsidiary of such successor corporation, held by Awardee at the time of termination, shall be accelerated in full. 

14. Amendment and Termination of the Plan.

(a) Amendment and Termination. The Administrator may amend, alter or discontinue the Plan or any Award
Agreement, but any such amendment shall be subject to approval of the stockholders of the Company in the manner and to the extent required by Applicable Law. To the extent required to comply with Section 162(m), the Company shall seek
re-approval of the Plan from time to time by the stockholders. In addition, without limiting the foregoing, unless approved by the stockholders of the Company, no such amendment shall be made that would: 

i. increase the maximum number of Shares for which Awards may be granted under the Plan, other than an increase
pursuant to Section 13 of the Plan; 
 ii. reduce the minimum exercise prices at which Options may be
granted under the Plan (as set forth in Section 8(b)); 
 iii. result in a repricing of Options or
Stock Appreciation Rights; or 
 iv. change the class of persons eligible to receive Awards under the Plan.

 (b) Effect of Amendment or Termination. No amendment, suspension or termination of the Plan
shall impair the rights of any Award, unless mutually agreed otherwise between the Participant and the Administrator, which agreement must be in writing and signed by the Participant and the Company; provided further that the

  

 20 

 
Administrator may amend an outstanding Award in order to conform it to the Administrator’s intent (in its sole discretion) that such Award not be subject to Code Section 409A(a)(1).
Termination of the Plan shall not affect the Administrator’s ability to exercise the powers granted to it hereunder with respect to Awards granted under the Plan prior to the date of such termination. 

(c) Effect of the Plan on Other Arrangements. Neither the adoption of the Plan by the Board or a
Committee nor the submission of the Plan to the stockholders of the Company for approval shall be construed as creating any limitations on the power of the Board or any Committee to adopt such other incentive arrangements as it or they may deem
desirable, including without limitation, the granting of restricted stock or stock options otherwise than under the Plan, and such arrangements may be either generally applicable or applicable only in specific cases. The value of Awards granted
pursuant to the Plan will not be included as compensation, earnings, salaries or other similar terms used when calculating an Awardee’s benefits under any employee benefit plan sponsored by the Company or any Subsidiary except as such plan
otherwise expressly provides. 
 15. Designation of Beneficiary.

(a) An Awardee may file a written designation of a beneficiary who is to receive the Awardee’s rights
pursuant to Awardee’s Award or the Awardee may include his or her Awards in an omnibus beneficiary designation for all benefits under the Plan. To the extent that Awardee has completed a designation of beneficiary while employed with the
Company, such beneficiary designation shall remain in effect with respect to any Award hereunder until changed by the Awardee to the extent enforceable under Applicable Law. 

(b) Such designation of beneficiary may be changed by the Awardee at any time by written notice. In the event of the
death of an Awardee and in the absence of a beneficiary validly designated under the Plan who is living at the time of such Awardee’s death, the Company shall allow the executor or administrator of the estate of the Awardee to exercise the
Award, or if no such executor or administrator has been appointed (to the knowledge of the Company), the Company, in its discretion, may allow the spouse or one or more dependents or relatives of the Awardee to exercise the Award to the extent
permissible under Applicable Law or if no spouse, dependent or relative is known to the Company, then to such other person as the Company may designate. 

16. No Right to Awards or to Employment.

No person shall have any claim or right to be granted an Award and the grant of any Award shall not be construed as giving an Awardee the
right to continue in the employ of the Company or its Affiliates. Further, the Company and its Affiliates expressly reserve the right, at any time, to dismiss any Employee, Consultant or Awardee at any time without liability or any claim under the
Plan, except as provided herein or in any Award Agreement entered into hereunder. 
  

 21 

 17. Legal Compliance.

Shares shall not be issued pursuant to the exercise of an Option or Stock Award unless the exercise of such Option or Stock Award and the
issuance and delivery of such Shares shall comply with Applicable Laws and shall be further subject to the approval of counsel for the Company with respect to such compliance. 

18. Reservation of Shares.

The Company, during the term of this Plan, will at all times reserve and keep available such number of Shares as shall be sufficient to
satisfy the requirements of the Plan. 
 19. Notice.

Any written notice to the Company required by any provisions of this Plan shall be addressed to the Secretary of the Company and shall be
effective when received. 
 20. Governing Law; Interpretation of Plan and Awards.

(a) This Plan and all determinations made and actions taken pursuant hereto shall be governed by the substantive
laws, but not the choice of law rules, of the state of Delaware. 
 (b) In the event that any provision of
the Plan or any Award granted under the Plan is declared to be illegal, invalid or otherwise unenforceable by a court of competent jurisdiction, such provision shall be reformed, if possible, to the extent necessary to render it legal, valid and
enforceable, or otherwise deleted, and the remainder of the terms of the Plan and/or Award shall not be affected except to the extent necessary to reform or delete such illegal, invalid or unenforceable provision. 

(c) The headings preceding the text of the sections hereof are inserted solely for convenience of reference, and
shall not constitute a part of the Plan, nor shall they affect its meaning, construction or effect. 

(d) The terms of the Plan and any Award shall inure to the benefit of and be binding upon the parties hereto and
their respective permitted heirs, beneficiaries, successors and assigns. 
 (e) All questions arising under
the Plan or under any Award shall be decided by the Administrator in its total and absolute discretion. In the event the Participant believes that a decision by the Administrator with respect to such person was arbitrary or capricious, the
Participant may request arbitration with respect to such decision. The review by the arbitrator shall be limited to determining whether the Administrator’s decision was arbitrary or capricious. This arbitration shall be the sole and exclusive
review permitted of the Administrator’s decision, and the Awardee shall as a condition to the receipt of an Award be deemed to explicitly waive any right to judicial review. 

 

 22 

 (f) Notice of demand for arbitration shall be made in writing to the
Administrator within thirty (30) days after the applicable decision by the Administrator. The arbitrator shall be selected from amongst those members of the Board who are neither Administrators nor Employees. If there are no such members of the
Board, the arbitrator shall be selected by the Board. The arbitrator shall be an individual who is an attorney licensed to practice law in the State of Washington. Such arbitrator shall be neutral within the meaning of the Commercial Rules of
Dispute Resolution of the American Arbitration Association; provided, however, that the arbitration shall not be administered by the American Arbitration Association. Any challenge to the neutrality of the arbitrator shall be resolved by the
arbitrator whose decision shall be final and conclusive. The arbitration shall be administered and conducted by the arbitrator pursuant to the Commercial Rules of Dispute Resolution of the American Arbitration Association. The decision of the
arbitrator on the issue(s) presented for arbitration shall be final and conclusive and may be enforced in any court of competent jurisdiction. 

21. Limitation on Liability.

The Company and any Affiliate which is in existence or hereafter comes into existence shall not be liable to a Participant, an Employee,
an Awardee or any other persons as to: 
 (a) The Non-Issuance of Shares. The non-issuance or
sale of Shares (including under Section 17 above) as to which the Company has been unable, or the Administrator deems it infeasible, to obtain from any regulatory body having jurisdiction the authority deemed by the Company’s counsel to be
necessary to the lawful issuance and sale of any shares hereunder; and 
 (b) Tax
Consequences. Any tax consequence realized by any Participant, Employee, Awardee or other person due to the receipt, vesting, exercise or settlement of any Option or other Award granted hereunder or due to the transfer of any Shares issued
hereunder. The Participant is responsible for, and by accepting an Award under the Plan agrees to bear, all taxes of any nature that are legally imposed upon the Participant in connection with an Award, and the Company does not assume, and will not
be liable to any party for, any cost or liability arising in connection with such tax liability legally imposed on the Participant. In particular, Awards issued under the Plan may be characterized by the Internal Revenue Service (the
“IRS”) as “deferred compensation” under the Code resulting in additional taxes, including in some cases interest and penalties. In the event the IRS determines that an Award constitutes deferred compensation under the Code
or challenges any good faith characterization made by the Company or any other party of the tax treatment applicable to an Award, the Participant will be responsible for the additional taxes, and interest and penalties, if any, that are determined
to apply if such challenge succeeds, and the Company will not reimburse the Participant for the amount of any additional taxes, penalties or interest that result. 

(c) Forfeiture. The requirement that Participant forfeit an Award, or the benefits received or to be
received under an Award, pursuant to any Applicable Law. 
  

 23 

 22. Unfunded Plan.

Insofar as it provides for Awards, the Plan shall be unfunded. Although bookkeeping accounts may be established with respect to Awardees
who are granted Stock Awards under this Plan, any such accounts will be used merely as a bookkeeping convenience. The Company shall not be required to segregate any assets which may at any time be represented by Awards, nor shall this Plan be
construed as providing for such segregation, nor shall the Company nor the Administrator be deemed to be a trustee of stock or cash to be awarded under the Plan. Any liability of the Company to any Participant with respect to an Award shall be based
solely upon any contractual obligations which may be created by the Plan; no such obligation of the Company shall be deemed to be secured by any pledge or other encumbrance on any property of the Company. Neither the Company nor the Administrator
shall be required to give any security or bond for the performance of any obligation which may be created by this Plan. 
  

 24Exhibit 4.1

 Exhibit 4.1 

SHARE EXCHANGE AGREEMENT 

THIS SHARE EXCHANGE AGREEMENT, dated as of May 14, 2010 (the “Agreement”), is by and among Markel Ventures, Inc., a
Virginia corporation (“Ventures”), AMF Holdco, Inc., a Virginia corporation (“AMF Holdco”), the shareholders of AMF Holdco set forth in Schedule A (each a “Shareholder” and collectively the “Shareholders”)
and, solely for the limited purposes expressly set forth below, Markel Corporation, a Virginia corporation (“Markel”). 

A. Each Shareholder is the sole record and beneficial owner of the shares of the common stock, no par value, of the AMF Holdco (“AMF
Holdco Common Stock”) set forth next to such Shareholder’s name in Schedule A (the “AMF Holdco Shares”). 

B. Ventures is the record and beneficial owner of 4,286.154570 shares of the outstanding AMF Holdco Common Stock. 

C. On the Closing Date (as defined below), the Shareholders will own in the aggregate 745.13795486 shares of AMF Holdco Common Stock.

 D. Ventures is a wholly owned subsidiary of Markel. 

E. Ventures and each Shareholder desires to exchange newly issued shares of Markel voting common stock, no par value (“Markel Common
Stock”), for such Shareholder’s AMF Holdco Shares on the terms set forth herein (the “Exchange”), in a transaction exempt from registration under the Securities Act of 1933, as amended (the “Securities Act”).

 In consideration of the mutual agreements and the representations and warranties contained in this Agreement and intending to
be legally bound, the parties agree as follows: 
 ARTICLE I 

SHARE EXCHANGE 

1.1 Share Exchange. Ventures agrees to deliver to each Shareholder the number of shares of Markel Common Stock (the “Markel
Common Shares”), and the amount of cash for fractional shares, set forth on Schedule A hereto in exchange for such Shareholder’s AMF Holdco Shares, and each Shareholder agrees to exchange all such Shareholder’s AMF Holdco Shares for
the Markel Common Shares and such amount of cash for fractional shares. 
 1.2 Surrender and Payment. 

(a) At the Closing (as defined below), each Shareholder will receive from Ventures a certificate representing such Shareholder’s
Markel Common Shares, and a check for the cash amount for fractional shares set forth in Schedule A, in exchange for the delivery to Ventures of one or more stock certificates evidencing such Shareholder’s AMF Holdco Shares, duly endorsed for
transfer or accompanied by appropriate transfer documents, with signatures guaranteed by a bank or registered broker-dealer, together with appropriate transfer stamps, if any. 

(b) If any certificate representing a Shareholder’s AMF Holdco Shares has been lost, stolen or destroyed, upon the making of an
affidavit of that fact by the Shareholder claiming such certificate to be lost, stolen or destroyed in a form reasonably satisfactory to Ventures, together with any indemnity bond that Ventures may reasonably request, Ventures will issue in exchange
for such lost, stolen or destroyed certificate the Redemption Consideration due with respect thereto. 
 1.3 Time and Place
of Closing. The transactions contemplated by this Agreement will be consummated (the “Closing”) at 10:00 a.m. at the offices of McGuireWoods LLP on the fifth business 

 
day after the date of this Agreement, or at such other place and time as may be agreed by the parties. The date on which the Closing occurs is the “Closing Date.” 

1.4 Transfer Restrictions; Legend. 

(a) The Markel Common Shares to be delivered to each Shareholder will not be registered under the Securities Act on the Closing Date and
may not be transferred, sold or otherwise disposed of by any Shareholder except pursuant to an effective registration statement under the Securities Act or in accordance with an exemption from the registration requirements of the Securities Act.

 (b) Each certificate representing Markel Common Shares delivered to the Shareholders in accordance with Section 1.4(a)
shall bear the following legend: 
 “THE SHARES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE
SECURITIES ACT OF 1933, AS AMENDED (“SECURITIES ACT”) OR ANY APPLICABLE SECURITIES LAWS OF ANY OTHER JURISDICTION. NEITHER THIS SECURITY NOR ANY INTEREST OR PARTICIPATION HEREIN MAY BE REOFFERED, SOLD, ASSIGNED, TRANSFERRED, PLEDGED,
ENCUMBERED OR OTHERWISE DISPOSED OF IN THE ABSENCE OF SUCH REGISTRATION OR UNLESS SUCH TRANSACTION IS EXEMPT FROM, OR NOT SUBJECT TO, REGISTRATION UNDER THE SECURITIES ACT AND SUBJECT TO COMPLIANCE WITH OTHER APPLICABLE LAWS. THE HOLDER HEREOF, BY
ITS ACCEPTANCE HEREOF, AGREES TO OFFER, SELL OR OTHERWISE TRANSFER SUCH SECURITY, UNLESS PREVIOUSLY REGISTERED UNDER THE SECURITIES ACT, ONLY PURSUANT TO AN AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT AND IN
COMPLIANCE WITH ALL APPLICABLE SECURITIES LAWS OF ANY OTHER RELEVANT JURISDICTION.” 
 (c) Removal of Legend. Markel
agrees to remove the legend contemplated by Section 1.4(b) (or any relevant portion thereof), by prompt delivery of substitute certificates upon the reasonable request of the holder if at such time such legend (or portion thereof) is no longer
required for purposes of, or applicable pursuant to, the prior provisions of this Section 1.4. 
 ARTICLE II 

REPRESENTATIONS AND WARRANTIES OF VENTURES 

Ventures represents and warrants to each Shareholder as follows: 

2.1 Corporate Status. Ventures is a corporation duly organized, validly existing and in good standing under the laws of Virginia.
Ventures has all requisite corporate power and authority to execute and deliver this Agreement and to perform its obligations under, and carry out the provisions of, this Agreement. 

2.2 Authorization; Binding Obligations; Governmental Consents. 

(a) All corporate action on the part of Ventures necessary for the authorization, execution and delivery of this Agreement and the
performance of its obligations hereunder has been taken. 
 (b) This Agreement has been duly executed and delivered by Ventures
and is the valid and legally binding obligation of Ventures, enforceable in accordance with its terms, except as enforceability may be limited by (i) applicable bankruptcy, insolvency, reorganization, moratorium, and other laws of general
application affecting enforcement of creditors’ rights, and (ii) the rules governing the availability of specific performance, injunctive relief or other equitable remedies and general principles of equity, regardless of whether considered
in a proceeding in law or equity. 
  

 2 

 (c) No consent, approval, permit, order or authorization of, or registration, qualification,
designation, declaration or filing with, any federal, state or local governmental authority on the part of Ventures is required in connection with the execution and delivery of this Agreement or the consummation of the transactions contemplated
hereby. 
 2.3 Compliance with Other Instruments. The execution, delivery and performance of this Agreement, and the
consummation of the transactions contemplated hereby, will not result in any violation of, or be in conflict with or constitute, with or without the passage of time or giving of notice, a default under any agreement, instrument, judgment, order,
writ, decree or contract to which Ventures or any of its subsidiaries is a party or by which Ventures’s or any of its subsidiaries’ properties are bound. 

2.4 Litigation. There are no actions, suits, proceedings or investigations pending or threatened against or involving Ventures
that question the validity of this Agreement or the taking of any action by Ventures hereunder or in connection herewith. 
 2.5
Consents. No permit, approval, authorization or consent of any person (other than any federal, state or local governmental authority) is required in connection with the execution, delivery and performance by Ventures of this Agreement or the
consummation of the transactions contemplated hereby. 
 2.6 Brokers. No finder, broker, agent or other similar
intermediary has acted for or on behalf of Ventures in connection with the negotiation of this Agreement or the consummation of the transactions contemplated hereby. 

ARTICLE III 

REPRESENTATIONS AND WARRANTIES OF MARKEL 

3.1 Corporate Status. Markel is a corporation duly organized, validly existing and in good standing under the laws of Virginia and
has all requisite corporate power and authority to execute and deliver this Agreement and to perform its obligations under, and carry out the provisions of, this Agreement. 

3.2 Authorization; Binding Obligations; Governmental Consents. 

(a) All corporate action on the part of Markel necessary for the authorization, execution and delivery of this Agreement and the
performance of its obligations hereunder has been taken. 
 (b) This Agreement has been duly executed and delivered by Markel
and is the valid and legally binding obligation of Markel, enforceable against Markel in accordance with its terms, except as enforceability may be limited by (i) applicable bankruptcy, insolvency, reorganization, moratorium, and other laws of
general application affecting enforcement of creditors’ rights, and (ii) the rules governing the availability of specific performance, injunctive relief or other equitable remedies and general principles of equity, regardless of whether
considered in a proceeding in law or equity. 
 (c) Except as contemplated by Article VII of this Agreement, no consent,
approval, permit, order or authorization of, or registration, qualification, designation, declaration or filing with, any federal, state or local governmental authority on the part of Markel is required in connection with the execution and delivery
of this Agreement and the consummation of the transactions contemplated hereby. 
 3.3 Compliance with Other Instruments.
The execution, delivery and performance of this Agreement will not result in any violation of, or be in conflict with or constitute, with or without the passage of time or giving of notice, a default under any agreement, instrument, judgment, order,
writ, decree or contract to which Markel is a party or by which its properties are bound. 
  

 3 

 3.4 Litigation. There are no actions, suits, proceedings or investigations pending or
threatened against or involving Markel that question the validity of this Agreement or the taking of any action by Markel hereunder or in connection herewith. 

3.5 Consents. No permit, approval, authorization or consent of any person (other than any federal, state or local governmental
authority) is required in connection with the execution, delivery and performance by Markel of this Agreement or the consummation of the transactions contemplated hereby.] 

3.6 Markel Common Shares. Each Markel Common Share to be delivered to the Shareholders shall, when delivered in accordance with
the terms of this Agreement at the Closing (i) be duly authorized, validly issued, fully paid and nonassessable and (ii) not have been issued in violation of any preemptive rights. 

3.7 Brokers. No finder, broker, agent or other similar intermediary has acted for or on behalf of Markel in connection with the
negotiation of this Agreement or the consummation of the transactions contemplated hereby. 
 ARTICLE IV 

REPRESENTATIONS AND WARRANTIES OF THE SHAREHOLDERS 

Each Shareholder severally represents and warrants to Ventures as follows: 

4.1 Corporate Status; Authorization. With respect to any Shareholder who is a corporation, such Shareholder: (i) is a
corporation duly organized, validly existing and in good standing under the laws of Virginia; (ii) has all requisite corporate power and authority to execute and deliver this Agreement and to perform its obligations under, and carry out the
provisions of, this Agreement; and (iii) has taken all corporate action on the part of such Shareholder necessary for the authorization, execution and delivery of this Agreement and the performance of its obligations hereunder. 

4.2 Binding Obligations; Governmental Consents. 

(a) This Agreement has been duly executed and delivered by such Shareholder and is the valid and legally binding obligation of such
Shareholder, enforceable in accordance with its terms, except as enforceability may be limited by (i) applicable bankruptcy, insolvency, reorganization, moratorium, and other laws of general application affecting enforcement of creditors’
rights, and (ii) the rules governing the availability of specific performance, injunctive relief or other equitable remedies and general principles of equity, regardless of whether considered in a proceeding in law or equity. 

(b) No consent, approval, permit, order or authorization of, or registration, qualification, designation, declaration or filing with, any
federal, state or local governmental authority on the part of such Shareholder is required in connection with the execution and delivery of this Agreement and the consummation of the transactions contemplated hereby. 

4.3 Compliance with Other Instruments. The execution, delivery and performance of this Agreement, and the consummation of the
transactions contemplated hereby, will not result in any violation of, or be in conflict with or constitute, with or without the passage of time or giving of notice, a default under any agreement, instrument, judgment, order, writ, decree or
contract to which such Shareholder is a party or by which such Shareholder or such Shareholder’s AMF Holdco Shares is bound, or result in the creation of any pledge, lien, charge or encumbrance upon the AMF Holdco Shares owned by such
Shareholder. 
 4.4 Ownership of AMF Holdco Shares. Such Shareholder is the sole record and beneficial owner of such
Shareholder’s AMF Holdco Shares, free of any pledge, lien, charge or encumbrance other than the transfer restrictions imposed by the AMF Holdco, Inc. Shareholders Agreement dated as of 

 

 4 

 
February 14, 2008 (the “Shareholders Agreement”); and as of the Closing Date the AMF Holdco Shares listed on Schedule A will constitute all of the capital stock of AMF Holdco
owned, in any capacity, by such Shareholder. 
 4.5 Litigation. There are no actions, suits, proceedings or
investigations pending or threatened against or involving such Shareholder that question the validity of this Agreement or the taking of any action by such Shareholder hereunder or in connection herewith. 

4.6 Consents. No permit, approval, authorization or consent of any person is required in connection with the execution, delivery
and performance by such Shareholder of this Agreement or the consummation of the transactions contemplated hereby. 
 4.7
Accredited Investor. Such Shareholder (i) is an “Accredited Investor” as defined in Regulation D under the Securities Act, (ii) has had the opportunity to ask such questions and receive such information concerning Markel
and Markel Common Stock as such Shareholder deems necessary, and (iii) is able to fend for himself, can bear the economic risk of the investment in Markel Common Stock, and has such knowledge and experience in financial and business matters
that such Shareholder is capable of evaluating the merits and risks of the investment in Markel Common Stock. 
 4.8 Markel
Information. In connection with this Agreement and the transactions contemplated hereby, such Shareholder is relying solely on the information relating to Markel’s business, finances and operations contained in filings by Markel with the
Securities and Exchange Commission and further acknowledges that neither Ventures nor Markel makes any representation or warranty with respect to any matters relating to Markel, its business, financial condition, results of operations, prospects or
otherwise, except to the extent expressly provided in Article III hereof. 
 4.9 Restricted Securities. Such
Shareholder understands that the Markel Common Shares being delivered in connection with the transactions contemplated by this Agreement have not been registered under the Securities Act. Such Shareholder further understands that (i) such
Markel Common Shares may not be sold, transferred or otherwise disposed of without registration under the Securities Act or an exemption therefrom, (ii) in the absence of an effective registration statement covering such securities or an
available exemption from registration under the Securities Act, such securities must be held indefinitely and (iii) certificates for the Markel Common Shares delivered to the Shareholder will bear the legend set forth in Section 1.4(b).

 4.10 AMF Holdco Information. AMF Holdco has made available to each Shareholder the (i) audited Consolidated
Balance Sheets, Statements of Operations, Statements of Members’ Equity and Statements of Cash Flows of AMF Automation Technologies, LLC, a Virginia limited liability company and wholly owned subsidiary of AMF Holdco (“AMF”), as of
December 31, 2009 and 2008 and for the years then ended and (ii) unaudited Consolidated Balance Sheet, Profit/Loss Statement and Statement of Cash Flows of AMF as of March 31, 2010 and for the quarterly period then ended
(collectively, the “AMF Financial Statements”). Such Shareholder has had the opportunity to review the AMF Financial Statements. Based on such Shareholder’s position with AMF or its subsidiaries, such Shareholder has sufficient
knowledge of AMF, its operations, prospects and financial position to determine whether or not to enter into this Agreement and has made such determination independently. 

ARTICLE V 

CLOSING 

5.1 Form of Documents; Deliveries. At Closing, subject to Sections 5.2 and 5.3, the parties will deliver the documents, and will
perform the acts, set forth in this Article V. All documents to be delivered at the Closing will be held in escrow by McGuireWoods LLP until the Closing Date, at which time they will be distributed to the appropriate parties. 

 

 5 

 5.2 Conditions to Closing on the Part of Ventures. The obligation of Ventures to
consummate the transactions contemplated by this Agreement will be subject to the following conditions: 
 (a) Each of the
representations and warranties of the Shareholders contained in this Agreement must have been true and correct in all material respects at the time originally made, and must be true and correct in all material respects as of the Closing with the
same force and effect as if such representations and warranties had been made at and as of the Closing; 
 (b) The Shareholders
must have performed and complied with all agreements, obligations and conditions contained in this Agreement that are required to be performed or complied with by them on or before the Closing Date; 

(c) All documents required to be delivered and actions required to be taken by the Shareholders under this Article V must have been
delivered or taken on or before the Closing Date; 
 (d) The newly issued Markel Common Shares to be delivered to each
Shareholder at the Closing shall have been issued and delivered to Ventures; 
 (e) The shares of AMF Holdco Common Stock owned
by Ventures together with the AMF Holdco Shares owned by the Shareholders as of the Closing Date must constitute all of the shares of the capital stock of AMF Holdco outstanding as of the Closing Date; and 

(f) No order, stay, decree, judgment or injunction has been entered, issued or enforced by any court of competent jurisdiction
prohibiting the transactions contemplated by this Agreement, and no litigation has been initiated questioning the validity of this Agreement or the taking of any action hereunder. 

5.3 Conditions to Closing on the Part of the Shareholders. The obligations of the Shareholders to consummate the transactions
contemplated by this Agreement will be subject to the following conditions: 
 (a) Each of the representations and warranties of
Ventures and Markel contained in this Agreement must have been true and correct in all material respects at the time originally made, and must be true and correct in all material respects as of the Closing with the same force and effect as if such
representations and warranties had been made at and as of the Closing; 
 (b) Ventures must have performed and complied with all
agreements, obligations and conditions contained in this Agreement that are required to be performed or complied with by them on or before the Closing Date; 

(c) All documents required to be delivered and actions required to be taken by Ventures under this Article V must have been delivered or
taken on or before the Closing Date; and 
 (d) No order, stay, decree, judgment or injunction has been entered, issued or
enforced by any court of competent jurisdiction prohibiting the transactions contemplated by this Agreement. 
 5.4
Deliveries by Ventures. Ventures will deliver to each Shareholder a certificate representing such Shareholder’s respective Markel Common Shares and a check for the amount of cash for such Shareholder’s fractional shares set forth in
Schedule A. 
 5.5 Deliveries by the Shareholders. Each Shareholder will deliver to Ventures one or more stock
certificates evidencing such Shareholder’s AMF Holdco Shares, duly endorsed for transfer or accompanied by appropriate transfer documents, with signatures guaranteed by a bank or registered broker-dealer, together with appropriate transfer
stamps, if any. 
  

 6 

 ARTICLE VI 

SHAREHOLDERS AGREEMENT 

Each of the parties hereto agrees that (i) the transfer restrictions set forth in the Shareholders Agreement will not apply to the
transactions contemplated hereby, and (ii) the Shareholders Agreement will terminate effective as of the Closing. 
 ARTICLE
VII 
 REGISTRATION RIGHTS 

7.1 Definitions. For all purposes of this Article VII, the following terms will have the meanings set forth below: 

“Best Efforts” will mean, with respect to any efforts undertaken by Markel under this Agreement to accomplish a
particular aim or satisfy a particular condition, Markel’s best efforts to cause such aim to be accomplished or such condition to be satisfied; provided, that Markel will not be deemed to be in breach of any obligation to use “Best
Efforts” under this Agreement to the extent that Markel is unable to cause an aim to be accomplished or a condition to be satisfied as a result of the refusal or inability of, or any delay on the part of, a third party to perform an action or
deliver a deliverable necessary to cause such aim to be accomplished or condition to be satisfied after Markel has undertaken all actions reasonably necessary to cause such third party to perform such action or deliver such deliverable. 

“Registrable Securities” will mean (i) the Markel Common Shares delivered to the Shareholders in connection with
the Exchange and (ii) any shares of Markel Common Stock issued as a dividend or other distribution with respect to, or in exchange for or in replacement of the shares referenced in clause (i). 

7.2 Registration Rights. 

(a) Registration. Markel will, after the Closing, use its Best Efforts to effect as expeditiously as possible, but within 120 days
after the Closing Date, the registration under the Securities Act of all the Registrable Securities that are then issued and outstanding. Markel will not be obligated to consummate more than one such registration. 

(b) Expenses of Registration. Markel will bear and pay all expenses incurred in connection with the registration, filing or
qualification of shares with respect to the registration under this Section 7.2 for the Shareholders, including, without limitation, all registration, filing, qualification, Blue Sky, printing and accounting fees relating or apportionable
thereto, but excluding applicable transfer taxes and expenses of counsel to the Shareholders, which will be borne by the Shareholders. 

(c) Rule 144 Reporting. With a view to making available the benefits of certain rules and regulations of the SEC which may permit
the sale of the Registrable Securities to the public without registration, Markel will: 
 (i) use its Best
Efforts to make and keep public information available, as those terms are understood and defined in Rule 144 under the Securities Act; 

(ii) use its Best Efforts to file with the SEC in a timely manner all reports and other documents required of Markel
under the Securities Act and the Exchange Act; and 
 (iii) furnish promptly to the Shareholders upon request
(a) a written statement by Markel as to its compliance with the reporting requirements of such Rule 144 and of the Securities Act and the Exchange Act, (b) Markel’s most recent SEC filings, and (c) such other information which
may reasonably be requested by the 
  

 7 

 
Shareholders to take advantage of any other rule or regulation of the SEC which permits Shareholders to sell their Markel Shares without registration; provided, that Markel will be deemed to have
furnished the Shareholders copies of any SEC filings that are available to the public on the SEC’s EDGAR website at www.sec.gov. 

(d) Obligations of Markel. Whenever required under this Section 7.2 to effect the registration of the Registrable Securities,
Markel will, as expeditiously as reasonably possible: 
 (i) Prepare and use its Best Efforts to file with the
SEC a registration statement within 120 days after the Closing Date with respect to such shares and use its Best Efforts to cause such registration statement to become and remain effective until the earlier of six months after the effective date of
the registration statement or the disposition of all securities covered by the registration statement; 
 (ii)
Prepare and use its Best Efforts to file with the SEC such amendments and supplements to such registration statement and the prospectus used in connection therewith as may be necessary to comply with the provisions of the Securities Act with respect
to the disposition of all securities covered by such registration statement; 
 (iii) Furnish to the
Shareholders such number of copies of a prospectus, including a preliminary prospectus, in conformity with the requirements of the Securities Act, and such other documents as they may reasonably request in order to facilitate the disposition of the
shares owned by them and covered by such registration statement; 
 (iv) Use its Best Efforts to register and
qualify the securities covered by such registration statement under such other securities or Blue Sky laws of such states or jurisdictions as may be reasonably requested by the Shareholders; provided, that Markel will not be required in
connection therewith or as a condition thereto to qualify to do business or to file a general consent to service of process in any such states or jurisdictions; 

(v) Notify the Shareholders as promptly as possible at any time when a prospectus relating to such registration statement
is required to be delivered under the Securities Act of the happening of any event as a result of which the prospectus included in such registration statement, as then in effect, includes an untrue statement of a material fact or omits to state a
material fact required to be stated therein or necessary to make the statements therein, in light of the circumstances under which they were made, not misleading and promptly prepare (and file with the SEC) and furnish to the Shareholders a
reasonable number of copies of a supplement to or an amendment of such prospectus as may be necessary so that, as thereafter delivered to the purchasers of Markel Common Stock covered thereby, such prospectus will not include an untrue statement of
a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein not misleading in the light of the circumstances then existing; 

(vi) Notify the Shareholders promptly of any request by the SEC for the amendment or supplement of such registration
statement or prospectus or for additional information, and notify the Shareholders promptly of the filing of each amendment or supplement to such registration statement or prospectus; 

(vii) Advise the Shareholders, promptly after it receives notice thereof, of the issuance of any stop order by the SEC
suspending the effectiveness of such registration statement or the initiation or threatening of any proceeding for that purpose and promptly use its reasonable efforts to prevent the issuance of any stop order or to obtain its withdrawal if such
stop order should be issued; and 
  

 8 

 (viii) Furnish to the Shareholders at least one conformed copy of the
registration statement and any amendments thereto. 
 (e) Obligations of Shareholders. In connection with any registration
required to be effected under this Section 7.2, the Shareholders will furnish to Markel such information regarding themselves, the shares held by them and the intended method of disposition of such shares as may be required to effect the
registration of its shares. 
 (f) Sale of Registrable Securities by Shareholders. The Shareholders may sell Registrable
Securities under an effective registration statement as long as, to the extent required by law, they arrange for delivery of a current prospectus and, if applicable, prospectus supplement to the transferee of such Registrable Securities. Upon the
sale of any Registrable Securities by the Shareholders under a registration statement, the Shareholders will deliver to Markel’s transfer agent, with a copy to Markel, a Certificate of Subsequent Sale substantially in the form attached to this
Agreement as Exhibit A so that the Registrable Securities may be properly transferred. 
 (g) Indemnification by Markel.
Markel will indemnify, to the extent permitted by law, the Shareholders and each of them against all losses, claims, damages, liabilities and expenses (under the Securities Act or common law or otherwise) caused by any untrue statement or alleged
untrue statement of a material fact contained in any registration statement or prospectus (as amended or supplemented if Markel has furnished any amendments or supplements thereto) or any preliminary prospectus or caused by any omission or alleged
omission to state therein a material fact required to be stated therein or necessary to make the statements therein not misleading, except insofar as such losses, claims, damages, liabilities or expenses are caused by any untrue statement or alleged
untrue statement contained in or by any omission or alleged omission from information furnished in writing to Markel by the Shareholders or either of them expressly for use therein. 

(h) Indemnification by Shareholders. The Shareholders and each of them will indemnify, to the extent permitted by law, Markel
against all losses, claims, damages, liabilities and expenses (under the Securities Act or common law or otherwise) caused by any untrue statement or alleged untrue statement of a material fact contained in any written material provided to Markel
under Section 7.2(e) above or caused by any omission or alleged omission to state therein a material fact required to be stated therein or necessary to make the statements therein not misleading, except to the extent that any untrue statement
or omission of a material fact was subsequently corrected by the Shareholders in a writing delivered to Markel before completion of the final prospectus. 

ARTICLE VIII 

INDEMNIFICATION 

8.1 General. From and after the Closing, the parties will indemnify each other as provided in this Article VIII. The
representations and warranties of Ventures and the Shareholders will survive Closing as provided in this Article VIII. 
 8.2
Certain Definitions. For purposes of this Article VIII, the following terms will have the indicated meanings: 
 (a)
“Damages” will mean all liabilities, demands, claims, actions or causes of action, regulatory, legislative or judicial proceedings or investigations, assessments, levies, losses, fines, penalties, damages, amounts paid in
settlement, costs and expenses, including reasonable attorneys’, accountants’, investigators’ and experts’ fees and expenses sustained or incurred in connection with the defense or investigation of any of the foregoing;

 (b) “Indemnified Party” will mean a party who is entitled to indemnification from another party under this
Article VIII; and 
  

 9 

 (c) “Indemnifying Party” will mean a party who is required to provide
indemnification under this Article VIII to another party. 
 8.3 Indemnification Obligations of Shareholders. Each
Shareholder will severally indemnify, save and keep harmless Ventures, Markel and their successors and assigns from all Damages sustained or incurred by any of them resulting from or arising out of or by virtue of: 

(a) Any breach of any representation or warranty made by such Shareholder in this Agreement or in any closing document delivered to
Ventures in connection with this Agreement; 
 (b) Any claim by any person to have a beneficial interest in the AMF Holdco
Shares shown to be owned by such Shareholder on Schedule A; or 
 (c) Any breach by such Shareholder of, or failure by such
Shareholder to comply with, any of its covenants or obligations under this Agreement; 
 8.4 Limitations on the
Shareholders’ Indemnification Obligations. The aggregate liability of any Shareholder in connection with such Shareholder’s indemnification obligation under Section 8.3(a) will not exceed the product of (i) the number of such
Shareholder’s AMF Holdco Shares times (ii) the AMF Holdco Common Stock Price per Share (as defined in Schedule A). 

8.5 Ventures’s Indemnification Obligations. Ventures will indemnify, save and keep harmless the Shareholders and their
respective successors and permitted assigns from all Damages sustained or incurred by any of them resulting from or arising out of or by virtue of: 

(a) Any breach of any representation or warranty made by Ventures or Markel in this Agreement or in any closing document delivered to the
Shareholders in connection with this Agreement; or 
 (b) Any breach by Ventures or Markel of, or failure by Ventures or Markel
to comply with, any of its respective covenants or obligations under this Agreement. 
 8.6 Subrogation. The Indemnifying
Party will not be entitled to require that any action be brought against any other person before action is brought against it hereunder by the Indemnified Party but will be subrogated to any right of action to the extent that it has paid or
successfully defended against any claim against an Indemnified Party by a person who is not a party to this Agreement. 
 ARTICLE
IX 
 MISCELLANEOUS 

9.1 Publicity. Press releases or other public statements concerning the transactions contemplated hereby may be made only by
Ventures or with its prior written consent. 
 9.2 Notices. All notices required or permitted to be given hereunder will
be in writing and may be delivered by hand, by facsimile, by nationally recognized private courier, or by United States mail. Notices delivered by mail will be deemed given three business days after being deposited in the United States mail, postage
prepaid, registered or certified mail. Notices delivered by hand, by facsimile, or by nationally recognized private courier will be deemed given upon receipt. All notices will be addressed as follows: 

If to Ventures or Markel: 

Markel Corporation 

4521 Highwoods Parkway 

Glen Allen, Virginia 23060 
  

 10 

 Facsimile: 804-965-1600 

Attention: Corporate Secretary 

If to a Shareholder, to the Shareholder’s address on Schedule A. 

and/or to such other addresses and/or addressees as may be designated by notice given in accordance with the provisions of this Section 9.2.

 9.3 Expenses. Each of the Shareholders, Ventures and Markel will bear all fees and expenses he or it incurs in
connection with the execution, delivery and performance of this Agreement and the consummation of the transactions contemplated hereby, including attorneys’, accountants’ and other professional fees and expenses. No fees or expenses of the
Shareholders will be paid by AMF Holdco. 
 9.4 Entire Agreement. This Agreement (including any exhibits and schedules)
and the instruments to be delivered by the parties under the provisions hereof constitute the entire agreement between the parties with respect to its subject matter and supersede all prior agreements between or among the parties with respect to its
subject matter. 
 9.5 Non-Waiver. The failure in any one or more instances of a party to insist upon performance of any
of the terms, covenants or conditions of this Agreement or to exercise any right or privilege conferred by this Agreement, or the waiver by such party of any breach of any of the terms, covenants or conditions of this Agreement, will not be
construed as a subsequent waiver of any such terms, covenants, conditions, rights or privileges. No waiver will be effective unless it is in writing and signed by an authorized representative of the waiving party. 

9.6 Counterparts. This Agreement may be executed in multiple counterparts, each of which will be deemed to be an original, and all
such counterparts will constitute but one instrument. 
 9.7 Severability. The invalidity of any provision of this
Agreement, or any portion of a provision, will not affect the validity of any other provision of this Agreement or the remaining portion of the applicable provision. 

9.8 Applicable Law. This Agreement will be governed by and interpreted in accordance with the laws of the Commonwealth of
Virginia. 
 9.9 Binding Effect; Benefit. This Agreement will inure to the benefit of and be binding upon the parties and
their successors and permitted assigns. Nothing in this Agreement, express or implied, is intended to confer on any person other than the parties and their respective successors and permitted assigns any rights, remedies, obligations or liabilities
under or by reason of this Agreement, including any third party beneficiary rights. 
 9.10 Assignability. This Agreement
will not be assignable by any Shareholder without the prior written consent of Ventures. 
 9.11 Amendments. This
Agreement may not be modified or amended except by an instrument in writing executed and delivered by the party to be charged with the modification or amendment. 

9.12 Headings; Interpretation. The headings contained in this agreement are for convenience of reference only and will not affect
the meaning or interpretation of this Agreement. Unless otherwise indicated, all references to sections, exhibits and schedules are to sections, exhibits and schedules of or to this Agreement. Unless the context requires otherwise, the word
“including” will be interpreted to mean “including without limitation.” The masculine gender includes the neuter, and the singular includes the plural, and vice versa. 

 

 11 

 9.13 Waiver of Jury Trial. EACH OF THE PARTIES WAIVES ANY RIGHT TO A JURY TRIAL IN
CONNECTION WITH ANY SUIT, ACTION OR PROCEEDING RELATING TO THIS AGREEMENT. 
 9.14 Termination. This Agreement and the
transactions contemplated hereby may be terminated and abandoned at any time before the Closing: 
 (a) By mutual written consent
of Ventures and all the Shareholders; 
 (b) By either Ventures or all the Shareholders if the Closing Date has not occurred by
July 1, 2010; or 
 (c) By either Ventures or all the Shareholders, if the terminating party is not then in material breach
of any representation, warranty or covenant in this Agreement and there has been a material breach by the other party of any of its representations, warranties or covenants under this Agreement which has not been cured on 10 days’ written
notice. 
 9.15 Plan of Reorganization. For United States federal income tax purposes it is intended by the parties that
the Exchange qualify as a “reorganization” within the meaning of Section 368(a) of the Internal Revenue Code of 1986, as amended (the “Code”). This Agreement is hereby adopted as a “plan of reorganization” for
purposes of Section 354 and 361 of the Code. 
 [Remainder of page intentionally left blank] 

 

 12 

 Each party has therefore caused this Agreement to be duly executed as of the day and year
first above written. 
  

			
	MARKEL VENTURES, INC.
		
	By	 	/s/ Thomas S. Gayner
	 Name:
 Title:
	 	 Thomas S. Gayner
 President

  

			
	AMF HOLDCO, INC.
		
	By	 	/s/ Ken Newsome
	 Name:
 Title:
	 	 Ken Newsome

President

  

			
	 SHAREHOLDERS:
  

Allegiant Corporation

		
	By	 	/s/ Ken Newsome
	 Name:
 Title:
	 	 Ken Newsome

President

  

	
	
	
	/s/ Bruce V. Campbell
	Bruce V. Campbell

  

	
	
	
	/s/ Austin Brockenbrough, III
	Austin Brockenbrough, III

 

	
	
	
	/s/ Margaret Shaia
	Margaret Shaia

  

	
	
	
	/s/ Tim Cook
	Tim Cook

  

			
	 Solely for purposes of Sections 1.4(c) and Article VII and the representations and warranties made in Article III of this
Agreement:
  
 MARKEL CORPORATION

		
	By	 	/s/ Thomas S. Gayner
	 Name:
 Title:
	 	 Thomas S. Gayner
 President

  

 13 

 SCHEDULE A 

 

							
	 Name and Address
	  	Shares of AMF Holdco Common
Stock (“AMF Holdco Shares”)	  	Shares of Markel Common Stock to
be Delivered (“Markel
Common
Shares”)	  	Cash for Fractional
Shares
	 Allegiant Corporation
 Attn:
Ken Newsome
 c/o AMF Automation Technologies, LLC

2115 W Laburnum Avenue
 Richmond, VA
23227
	  	395.95730738	  	10,385	  	$123.88
				
	 Bruce V. Campbell
 AMF
Automation Technologies, LLC
 2115 W Laburnum Avenue

Richmond, VA 23227
	  	113.77906009	  	2,984	  	$88.52
				
	 Austin Brockenbrough, III
 Lowe
Brockenbrough & Co.
 1802 Bayberry Court, Suite 400

Richmond, VA 23226-3767
	  	199.75764639	  	5,239	  	$118.91
				
	 Margaret Shaia
 AMF Automation
Technologies, LLC
 2115 W Laburnum Avenue

Richmond, VA 23227
	  	18.00199041	  	472	  	$58.46
				
	 Tim Cook
 AMF Automation
Technologies, LLC
 2115 W Laburnum Avenue

Richmond, VA 23227
	  	17.64195060	  	462	  	$256.42

  

 14 

 Exhibit A 

Certificate of Subsequent Sale 

Markel Corporation 
 4521 Highwoods Parkway

 Glen Allen, Virginia 23060 

Attention: Corporate Secretary 
 Dear Sir:

 We have been requested to act as broker or dealer in connection with the sale of the following shares of Markel Corporation: 

Selling Stockholder: 

No. of Shares Sold: 

Registration Statement: 333- 

Date of Prospectus: 

Trade Date(s): 

In connection therewith, the undersigned hereby certifies that the number of shares sold, as indicated above, were sold for the account of the registered
owner in accordance with the above-referenced prospectus. A copy of the prospectus was properly delivered in accordance with the prospectus delivery requirements of Section 5(b)(2) of the Securities Act of 1933, as amended. Please authorize the
transfer of these shares without further restriction. 
 Thank you for your assistance in this matter. 

 

			
	 Sincerely,
  

[FIRM NAME]

		
	By:	 	 
	Print name: Title:	 	

  

 15

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