Document:

Exhibit 10.9

 

Certain identified
information has been excluded from the exhibit pursuant to Item 601(a)(6) of Regulation S-K due to personal privacy concerns or pursuant
to Item 601(b)(10)(iv) because it is both not material and is the type of information that the registrant treats as private or confidential.
Redacted information is indicated by: [***]

 

ADVISORY CONSULTING AGREEMENT

 

THIS
AGREEMENT is dated as of May 26, 2021 (the “Effective Date”)

 

BETWEEN:

 

ProMIS
Neurosciences Inc., a corporation existing under the federal laws of Canada with a registered address at 1920 Yonge St., Suite 200,
Toronto, Ontario, M4S 3E2

 

(the “Company”)

 

AND:

 

David Wishart, PhD

 

with an address at [***],

 

[***]

 

(the “Advisor”)

 

WHEREAS:

 

		A.	The Company wishes to engage the Advisor as the Company’s Chief Physics Officer and

 

IN
CONSIDERATION OF the mutual covenants and agreements contained herein, and other good and valuable consideration, the receipt
and sufficiency of which is hereby mutually acknowledged, the parties agree as follows:

 

PROVISION OF SERVICES

 

1.            Services.
Commencing on May 26, 2021 (the “Start Date”), the Advisor will perform for the Company (as an independent contractor
and not as employee, agent, partner or joint venturer) the services described in Schedule A (collectively, the “Services”).
Schedule A forms an integral part of this Agreement and is hereby incorporated by reference.

 

2.            Quality
of Service. The Advisor represents, warrants, and covenants that it will (and will cause the Advisor Representatives to) a) perform
the Services in a timely, competent and professional manner in accordance with the standards and practices commonly expected of qualified
and experienced providers of similar services, (b) perform the Services in compliance with all applicable laws, rules, ordinances
and regulations that are now applicable to the Advisor, the Advisor Representatives or the Services, whether federal, state, provincial,
municipal or otherwise, and (c) at all times act in the best interests of the Company and perform the Services in a faithful manner
to the best ability of the Advisor and each of the Advisor Representatives.

 

3.            Subcontracting
and Assignment. The Advisor will not, without the prior written consent of the Company (which consent the Company may in its sole
discretion withhold), subcontract, delegate or otherwise assign any or all of the Advisor’s obligations under this Agreement.

 

    

     

    

 

TERM AND TERMINATION

 

4.            Term.
The term of this Agreement will be twelve months from the effective date. This contract may be renewed for a subsequent period or periods
of 12 months, upon mutual consent of both parties. This agreement may be terminated by either Party, as described in Schedule A. Effect
of Termination. If this Agreement is terminated as provided herein, the Company’s sole liability shall be to pay the Advisor
for all properly performed Services to the effective date of termination and neither the Advisor nor the Advisor Representatives will
have any other claim for compensation, losses, costs or damages of any nature or kind based on such termination. All obligations and rights
that, by their nature, are intended to survive the termination or expiration of this Agreement will so survive.

 

FEES AND EXPENSES

 

5.            Fees
and Expenses.

 

In consideration for performing the Services,
exchange for the advice and services to be provided by the Consultant as set out in Section 1.0 and Appendix A, ProMIS agrees to
pay and the Consultant hereby acknowledges that the following compensation represents payment in full for such services and advice:

 

		(a)	ProMIS shall, on the basis of monthly invoices from Consultant, pay Consultant for his services at the
rate of CDN $[***] ([***] Canadian dollars) per month (plus GST if applicable). During the contract term, it is understood that the Consultant
shall be available for the requirements of ProMIS to achieve the goals and objectives set out in Appendix A. During the contract term,
it is also understood that the Consultant will devote, on average over any calendar month, up to one day per week of his time to achieve
the Objectives set forth in Appendix A.

 

		(b)	ProMIS will grant the Advisor [***] share options in the Corporation, at a strike price equal to the volume
weighted average share price of the preceding 5 days. One third of the share options will vest immediately, and the remainder will vest
in equal monthly portions over 24 months. In case of change of control, all options, whether vested or not will immediately vest. The
Company will reimburse the Advisor in accordance with its normal policies and practices for the Advisor’s reasonable, out-of-pocket
expenses or disbursements actually and necessarily incurred or made by the Advisor in connection with the performance of the Services
(collectively, “Expenses”). All reasonable business-related expenses will be reimbursed upon submission of receipts and expense
reimbursement request. Any individual expense exceeding US $500.00 (five hundred US dollars) requires advance written approval from ProMIS
Neurosciences.

 

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6.            Taxes
and Benefits. The Advisor represents, warrants and covenants that the Advisor is acting and will act only as independent contractor
(and, in any event, never as an employee of the Company). The Advisor acknowledges and agrees that, in its performance under this Agreement,
neither the Advisor nor either Advisor Representative, will be entitled to any employee-like benefits or any direct or indirect compensation
other than that expressly set out in this Agreement. The Advisor will, as an independent contractor, collect and/or remit as required,
all amounts, and will register with any workers’ compensation entities or other governmental bodies, and deal with all tax and other
requirements, and satisfy all applicable compliance requirements, as required or permitted under law by all municipal, provincial, state
or federal governments. The Advisor agrees that the Company will not be responsible for registering under any workers’ compensation
legislation or for withholding or remitting any amounts for income taxes, social security taxes, (un)employment insurance, or other deductions
that would be required in an employment relationship in any jurisdiction.

 

CONFIDENTIALITY AND RESTRICTIVE COVENANTS

 

7.            Definitions.
In this Agreement,

 

		(a)	“Company Entities” means the Company and its subsidiary, parent and affiliate corporations,
to the extent that such reference does not require any subsidiary party to be added as a party to this Agreement other than as a third
party beneficiary, each of whom will be expressly deemed an intended third party beneficiary of this Agreement and will have the right
to enforce the terms and conditions of this Agreement; and

 

		(b)	“Confidential Information” means all information in any form (including all electronic,
magnetic, physical, intangible, visual and oral forms) and whether or not such information has been marked or indicated as confidential,
that is known, held, used or disclosed by or on behalf of the Company Entities in connection with its business, and that, at the time
of its disclosure: (i) is not available or known to the general public; (ii) by its nature or the nature of its disclosure,
would reasonably be determined to be confidential; or (iii) is marked or indicated as proprietary or confidential; and includes patent
applications, trade secrets, technology, know-how, technical information, supplier and customer information (whether past, present, future
and prospective), strategic plans, financial information, marketing information, information as to business opportunities, strategies
and research and development, consultation records and plans, communications, meetings, conversations, surveys, third party data and studies.

 

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8.            Confidentiality.
In connection with the Advisor’s performance under this Agreement, the Company has furnished or may furnish to the Advisor, or the
Advisor may acquire, develop or conceive of, Confidential Information, all of which the Advisor will treat strictly in accordance with
this Agreement. For greater clarity, the parties hereby acknowledge and agree that Confidential Information can encompass information
regardless of whether it was disclosed prior to the date of this Agreement or after. In connection with this,

 

		(a)	Obligations-at all times during and after this Agreement (subject to §8(b)), the Advisor
will protect the Confidential Information using a reasonable degree of care, and will take all reasonable steps to safeguard the Confidential
Information from unauthorized disclosure, and without limiting the foregoing will not, directly or indirectly, (i) copy or reproduce
any of the Confidential Information, (ii) use any Confidential Information for any purpose other than the proper performance of the
Advisor’s duties, or (iii) subject to §8(c), disclose any of the Confidential Information except strictly to those of
the Company’s directors, officers, Advisors, attorneys, accountants, advisors and personnel to whom disclosure is necessary to carry
out the Advisor’s duties,

 

		(b)	Exceptions-this §8 imposes no obligation upon any person with respect to any information
or part thereof that the Advisor can establish that, other than as a result of a breach of this Agreement, (i) was in the Advisor’s
possession prior to entering into this Agreement without any restriction of confidentiality owed to any Company Entity, (ii) is or
becomes generally available to the public rightfully without restrictions of confidentiality, or (iii) becomes available to the Advisor
after the term of this Agreement from a third party (other than any Company Entity) who has no obligation of confidentiality with respect
thereto,

 

		(c)	Required Disclosures-if the Advisor is requested or required (including, without restriction,
by oral questions, interrogatories, requests for information or documents, subpoena, civil investigative demand or other similar process)
by any law to disclose any Confidential Information, he may disclose strictly that Confidential Information for which disclosure is required
to comply with any such applicable law, provided that the Advisor (i) unless prohibited by such applicable law, provides the Company
with written notice as soon as practicable in the circumstances so that the Company may contest the disclosure or seek an appropriate
protective order, and (ii) cooperates reasonably and in good faith with the Company in its efforts to prevent, restrict or contest
such required or requested disclosure.

 

		(d)	Acknowledgement-the Advisor acknowledges and agrees that the right to maintain the confidentiality
of Confidential Information, and the right to preserve the Company’s goodwill therein, constitute proprietary rights which the Company
is entitled to protect.

 

GENERAL PROVISIONS

 

9.            No
Liability. In no event will the Company or its Company Entities be liable for any claims made by the Advisor, the Advisor Representatives
or any third party for any special, indirect, incidental, or consequential damages in connection with this Agreement, whether for negligence
or breach of contract, including without limitation loss of business opportunities, profits or revenues, and whether or not the possibility
of such damages or loss of opportunities, profits or revenues has been disclosed by the Advisor in advance or could have been reasonably
foreseen by the Company. The Company’s liability for any and all direct damages in connection with this Agreement will not, in any
event, in aggregate exceed the total fees actually paid or payable to the Advisor for the Services performed under the terms of this Agreement.

 

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10.          Severability.
If any provision of this Agreement is held invalid, illegal or unenforceable, the remaining provisions will not be affected.

 

11.          Governing
Law. This Agreement will be governed by and interpreted in accordance with the laws of the Province of British Columbia and the laws
of Canada applicable therein without reference to its conflict of laws principles.

 

12.          Notice.
Every notice, request, demand or direction (each, for the purposes of this section, a “notice”) to be given pursuant
to this Agreement by either party to another will be in writing and will be delivered or sent by registered or certified mail postage
prepaid and mailed in any government post office or by email, or other similar form of written communication, in each case, addressed
as above or to another address as notified hereunder from time to time.

 

13.          Interpretation.
In this Agreement, (a) “§” means a section, subsection, paragraph or sub-paragraph of this Agreement and
 “Part” means a captioned part of this Agreement, (b) any word in this Agreement is deemed to include the masculine, feminine,
neuter, singular or plural form thereof as the context so required, (c) the captions and headings used in this Agreement are for
convenience only and do not constitute substantive matter and are not to be construed as interpreting the contents of this Agreement,
and (d) the word “including” is not limiting (whether or not non-limiting language such as “without limitation”
or “but not limited to” or other words of similar import are used with reference thereto).

 

14.          Entire
Agreement. This Agreement, including all Schedules hereto, forms the entire agreement among the parties and supersedes all prior
agreements, proposals or communications relative to the subject matter of this Agreement. Amendments to or waivers of this Agreement
will be effective only if in writing and signed by authorized representatives of all parties. Unless otherwise expressly
stated, if there is any necessary conflict between any of the terms of this Agreement and Schedules to this Agreement, this
Agreement will take precedence.

 

15.          Acceptance.
This Agreement is executed effective as of the day and year first above written and may be executed in counterparts, each of which
will constitute an original and all of which taken together will constitute one and the same instrument, and delivery of the counterparts
may be effected by means of electronic transmission. The reproduction of signatures by electronic transmission will be treated as binding
as if originals.

 

ProMIS Neurosciences Inc.

 

	Per:	/s/ Elliot Goldstein	 
	 	Dr. Elliot P Goldstein, President and CEO	 

 

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Advisor

 

	Per:	/s/ David Wishart 	 
	 	David Wishart, PhD	 

 

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SCHEDULE A

 

[Intentionally omitted]

 

    7Exhibit 10.10 

 

Certain identified information has been excluded from the
exhibit pursuant to Item 601(a)(6) of Regulation S-K due to personal privacy concerns. Redacted information is indicated by: [***]

 

CONSULTING
AND ADVISORY AGREEMENT

 

THIS AGREEMENT MADE
AS OF THE 1st DAY OF MARCH, 2005 (the “Effective Date”).

 

BETWEEN:

 

AMORFIX
LIFE SCIENCES LTD., a company incorporated under the laws of Canada having a business office
care of TANZ Neurosciences Building, 6 Queen’s Park Crescent West, Toronto, Ontario, M5S 3H2;

 

(the “Company”)

 

AND:

 

NEIL
CASHMAN, having a business address care of [***];

 

(the “Consultant”)

 

WHEREAS the Consultant
is the scientist behind the Prion technology used by the Company (the “Expertise”);

 

AND WHEREAS the Company
would like to engage the Consultant to provide services to the Company as the Chairman of the Board and Chief Scientific Officer of the
Company;

 

NOW THEREFORE THIS
AGREEMENT WITNESSES that in consideration of the mutual covenants and agreements herein contained, the parties hereto agree (the “Agreement”)
as follows:

 

1.            Engagement

 

		1.1	During
                                            the Term of this Agreement, the Consultant will provide the Services described on Schedule
                                            “A” hereto to the Company (the “Services”).

 

		1.2	This
                                            Agreement shall be in effect (the “Term”) until terminated by either party. The
                                            Consultant may terminate on 30 days written notice to the Company, and the Company on 6 months
                                            written notice to the Consultant.

 

		1.3	The
                                            Consultant is cognizant of the sensitive and confidential nature of the interactions contemplated
                                            under this Agreement and, in this regard, agrees to adhere to high ethical standards when
                                            carrying out its engagement. In providing his Services to the Company hereunder, the Consultant
                                            will:

 

		(a)	act
                                            honestly, in good faith and in the best interests of the Company;

 

		(b)	exercise
                                            the care and diligence of a prudent advisor and consultant; and

 

		(c)	use
                                            his best efforts to well and faithfully serve the interests of the Company.

 

		1.4	The
                                            parties may elect, at any time, by mutual agreement, to turn this relationship from a consulting
                                            relationship to an employment relationship, and amend the terms of this Agreement accordingly.

 

    

     

    

 

2.            Remuneration

 

		2.1	For
                                            providing his Services, the Company will:

 

		(a)	pay
                                            to the Consultant a consultancy and advisory fee (the “Fee”) of $5,000 per month,
                                            plus GST, commencing for the month of March, 2005; and

 

		(b)	reimburse
                                            the Consultant for all reasonable expenses (the “Expenses”) incurred by the Consultant
                                            in meeting its obligations hereunder, provided any Expenses exceeding $200 per month are
                                            pre-approved, such approval not to be unreasonably withheld.

 

		2.2	The
                                            Consultant will invoice the Company, no less frequently than monthly, for all Fees and Expenses
                                            incurred. Invoices will be due for payment immediately upon delivery to the Company and should
                                            the Company not pay the full amount outstanding on the invoice to the Consultant within 10
                                            days of receipt of the invoice, interest will accrue on the outstanding balance at a rate
                                            of 18% per annum. If this Agreement is terminated during a calendar month, the Fees will
                                            be prorated for that month to the termination date.

 

		2.3	The
                                            Company will grant to the Consultant, from time to time, stock options to acquire shares
                                            of the Company. The terms and conditions of the stock options will be in accordance with
                                            the stock option plan then in effect and will be subject to the approval of the Board of
                                            the Company. The number of stock options will be an amount that properly reflects the position
                                            of the Consultant with the Company when put in context of the overall organization of the
                                            Company, and the exercise price will be at least as favourable as for other stock options
                                            being granted.

 

3.            Confidentiality
and Protection of Interests

 

		3.1	Each
                                            party will keep this Agreement and all aspects of it confidential during the Term of this
                                            Agreement and for a period of two years thereafter.

 

		3.2	The
                                            Consultant shall not, during the Term of this Agreement or at any time thereafter, use for
                                            his own purposes or for any purposes other than those of the Company any intellectual property
                                            or knowledge or confidential information of any kind whatsoever he may acquire in relation
                                            to the Company’s business or the business of its subsidiaries, and such shall be and
                                            remain the property of the Company.

 

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4.            General

 

		4.1	The
                                            headings and section references in this Agreement are for convenience of reference only and
                                            do not form a part of this Agreement and are not intended to interpret, define or limit the
                                            scope, extent or intent of this Agreement or any provision thereof.

 

		4.2	Time
                                            is hereby expressly made of the essence of this Agreement with respect to the performance
                                            by the parties of their respective obligations under this Agreement.

 

		4.3	This
                                            Agreement shall enure to the benefit of and be binding upon the parties hereto and their
                                            respective heirs, executors, administrators, personal representatives, successors and permitted
                                            assigns. This Agreement may not be assigned by either party hereto without the prior express
                                            written consent of the other party.

 

		4.4	This
                                            Agreement constitutes the entire agreement between the parties hereto relating to the subject
                                            matter hereof and may not be amended, waived or discharged except by an instrument in writing
                                            executed by the party against whom enforcement of such amendment, waiver or discharge is
                                            sought and this Agreement supersedes all prior agreements between the parties.

 

		4.5	Each
                                            of the parties hereto hereby covenants and agrees to execute such further and other documents
                                            and instruments and do such further acts and other things as may be necessary to implement
                                            and carry out the intent of this Agreement.

 

		4.6	All
                                            notices, requests, demands and other communications hereunder shall be in writing and shall
                                            be deemed to have been duly given if sent or delivered as follows:

 

	 	   To
                    the Company:

	 	 	 
	 	 	Amorfix Life Sciences Ltd.
	 	 	c/o [***]

 

	 	   Attention:	Dr. Vigen Nazarian, President & acting CEO
	 	   Email:	[***]

 

	 	   To
                    the Consultant: 

	 	 
	 	 	Neil Cashman
	 	 	c/o [***]

 

	 	   Email:	[***]

 

or to such other address
as may be given in writing by the Company or the Consultant.

 

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IN WITNESS WHEREOF
this Agreement has been duly executed by the parties hereto effective as of the day and year first above written.

 

	Signed, sealed
                           and delivered by AMORFIX LIFE SCIENCES LTD. per:
	 
	 	 
	/s/ Vigen Nazarian	 
	Dr. Vigen Nazarian	 

 

	SIGNED,
                                            SEALED and DELIVERED by NEIL CASHMAN in the presence of:
	)	 
	 	)	 
	/s/	)	/s/ Neil Cashman
	Signature of Witness	)	NEIL CASHMAN
	 	)	 
	 	)	 
	Name of Witness	)	 
	 	)	 
	 	)	 
	Address of Witness	)	 
	 	)	 
	 	)	 
	 	)	 
	 	)	 
	Scientist	)	 
	Occupation of Witness	)	 

 

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SCHEDULE
 “A”

 

DESCRIPTION
OF SERVICES

 

[Intentionally
omitted]

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