Document:

Exhibit 10.3

 

 

 

 

 

 

ACASTI PHARMA inc.

 

STOCK OPTION PLAN

AS AMENDED August 27, 2020

 

 

 

 

 

 

 

 

 

 

 

 

 

 

     

     

    

acasti pharma inc.

 

STOCK OPTION PLAN

THIS PLAN adopted October 8, 2008, amended on April 29, 2009,
March 1, 2011, May 22, 2013, October 5, 2015, May 11, 2016, June 8, 2017, July 27, 2018, April 15, 2019, March 31, 2020 and August 27,
2020.

Article 1

DEFINITIONS AND INTERPRETATION

1.1                                     
Definitions. Where used in this Plan, unless there is something in the subject matter or context
inconsistent therewith, the following terms will have the meanings set forth below:

		(a)	"Associate" has the meaning ascribed to it in the Securities
Act.

		(b)	"Board" means the board of directors of the Corporation,
or any duly appointed committee thereof to which the board of directors of the Corporation has delegated the power to administer and grant
Options under this Plan, as constituted from time to time.

		(c)	"Cause" means, with respect to a particular Employee:

		(i)	"cause" as such term is defined in the written employment agreement
between the Corporation and the Employee; or

		(ii)	in the event there is no written employment agreement between the Corporation
and the Employee or "cause" is not defined in the written employment agreement between the Corporation and the Employee, the
usual meaning of cause under the laws of the Province of Québec.

		(d)	Change of Control” means: 

		(i)	a consolidation, reorganization, amalgamation, merger, acquisition or other
business combination (or a plan of arrangement in connection with any of the foregoing), other than solely involving the Corporation and
any one or more of its Associates, with respect to which all or substantially all of the Persons who were the beneficial owners of the
Shares and other securities of the Corporation immediately prior to such consolidation, reorganization, amalgamation, merger, acquisition,
business combination or plan of arrangement do not, following the completion of such consolidation, reorganization, amalgamation, merger,
acquisition, business combination or plan of arrangement, beneficially own, directly or indirectly, more than 50% of the resulting voting
rights (on a fully-diluted basis) of the Corporation or its successor; 

		(ii)	a resolution is adopted to wind-up, dissolve or liquidate the Corporation;

		(iii)	the sale, exchange or other disposition to a person other than an Affiliate
of the Corporation of all or substantially all of the Corporation’s assets; or 

		(iv)	a change in the composition of the Board, which occurs at a single meeting
of the shareholders of the Corporation or upon the execution of a shareholders’ resolution, such that individuals who are members
of the Board immediately prior to such meeting or resolution cease to constitute a majority of the Board, without the Board, as constituted
immediately prior to such meeting or resolution, having approved of such change; 

     

    	 	-2-	 

    
		(e)	“Code” has the meaning given in Section 7.1 of this Plan.

		(f)	"Company" means, unless specifically indicated otherwise,
a corporation, incorporated association or organization, body corporate, partnership, trust, association, or other entity other than an
individual.

		(g)	"Consultant" means a person, other than an Employee or
Director of the Corporation, or a Company, who:

		(i)	provides on a bona fide basis consulting, technical, management or
other services to the Corporation or a Subsidiary of the Corporation under a written contract;

		(ii)	possesses technical, business, management or other expertise of value to
the Corporation or a Subsidiary of the Corporation;

		(iii)	in the reasonable opinion of the Corporation, spends or will spend a significant
amount of time and attention on the business and affairs of the Corporation or a Subsidiary of the Corporation; and

		(iv)	has a relationship with the Corporation or a Subsidiary of the Corporation
that enables the individual to be knowledgeable about the business and affairs of the Corporation.

		(h)	"Corporation" means Acasti Pharma Inc., and includes any
successor corporation thereto.

		(i)	"Director" means a member of the board of directors of
the Corporation or a member of the board of directors of a Subsidiary of the Corporation to whom stock options may be granted in reliance
on a prospectus exemption under applicable Securities Laws.

		(j)	"Effective Date" means the effective date of this Plan,
as amended, being October 8, 2008.

		(k)	"Employee" means an individual who:

		(i)	is considered an employee of the Corporation or a Subsidiary of the Corporation
under the Income Tax Act (Canada) (i.e., for whom income tax, employment insurance and CPP deductions must be made at source);

		(ii)	works full-time for the Corporation or a Subsidiary of the Corporation providing
services normally provided by an employee and who is subject to the same control and direction by the Corporation or a Subsidiary of the
Corporation over the details and methods of work as an employee of the Corporation, but for whom income tax deductions are not made at
source; or

		(iii)	works for the Corporation or a Subsidiary of the Corporation on a continuing
and regular basis for a minimum amount of time per week providing services normally provided by an employee and who is subject to the
same control and direction by the Corporation or a Subsidiary of the Corporation over the details and methods of work as an employee of
the Corporation, but for whom income tax deductions are not made at source.

     

    	 	-3-	 

    
		(l)	"Exchange" means the TSX Venture Exchange and, where the
context permits, any other exchange on which the Shares are or may be listed from time to time.

		(m)	"Exercise Notice" means the notice respecting the exercise
of an Option, in the form set out in the Option Agreement, duly executed by the Option Holder. 

		(n)	"Exercise Period" means the period during which a particular
Option may be exercised and, subject to earlier termination in accordance with the terms hereof, is the period from and including the
Grant Date through to and including the Expiry Date.

		(o)	"Exercise Price" means the price per Share at which Shares
may be purchased under an Option duly granted under this Plan, as determined in accordance with Section 4.3 of this Plan and, if applicable,
adjusted in accordance with Section 3.5 of this Plan.

		(p)	"Expiry Date" means the date determined in accordance with
Section 4.2 of this Plan and after which a particular Option cannot be exercised and is deemed to be null and void and of no further force
or effect.

		(q)	"Grant Date" means the date on which the Board grants a
particular Option.

		(r)	"Insider" means an “insider” as defined by
the Exchange from time to time in its rules and regulations. 

		(s)	“ISOs” has the meaning given in Section 7.1 of this Plan.

		(t)	"Market Price" at any date in respect of the Shares shall
be the closing price of such Shares on the Exchange (and if listed on more than one stock exchange, then the highest of such closing prices)
on the last Business Day prior to the Grant Date (or, if such Shares are not then listed and posted for trading on the Exchange, on such
stock exchange in Canada on which the Shares are listed and posted for trading as may be selected for such purpose by the Board). In the
event that such Shares did not trade on such Business Day, the Market Price shall be the average of the bid and asked prices in respect
of such Shares at the close of trading on such date. In the event that such Shares are not listed and posted for trading on any stock
exchange, the Market Price shall be the fair market value of such Shares as determined by the Board in its sole discretion;

		(u)	"Option" means an option to acquire Shares granted to a
Director, Employee or Consultant of the Corporation, or any Subsidiary of the Corporation pursuant to this Plan.

		(v)	"Option Agreement" means an agreement, in the form substantially
similar as that set out in Schedule "A" hereto, evidencing an Option granted under this Plan.

		(w)	"Option Holder" means a Director, Employee or Consultant
or former Director, Employee or Consultant, to whom an Option has been granted and who continues to hold an unexercised and unexpired
Option or, where applicable, the Personal Representative of such person.

     

    	 	-4-	 

    
		(x)	"Plan" means this stock option plan, as may be amended
from time to time.

		(y)	"Person" means a Company or an individual.

		(z)	"Personal Representative" means:

		(i)	in the case of a deceased Option Holder, the executor or administrator of
the deceased duly appointed by a court or public authority having jurisdiction to do so; and

		(ii)	in the case of an Option Holder who, for any reason, is unable to manage
his or her affairs, the individual entitled by law to act on behalf of such Option Holder.

		(aa)	"QBCA" means the Business Corporations Act (Québec),
as amended, or such other successor legislation which may be enacted, from time to time.

		(bb)	"Regulatory Authorities" means the Exchange and any other
organized trading facilities on which the Corporation's Shares are listed and all securities commissions or similar securities regulatory
bodies having jurisdiction over the Corporation.

		(cc)	"Re-Organization Event" has the meaning given in Section
3.5 of this Plan.

		(dd)	"Securities Act" means the Securities Act (Québec),
as amended, or such other successor legislation as may be enacted, from time to time.

		(ee)	"Securities Laws" means securities legislation, securities
regulation and securities rules, as amended, and the policies, notices, instruments and blanket orders in force from time to time that
govern or are applicable to the Corporation or to which it is subject, including, without limitation, the Securities Act.

		(ff)	"Share" means one (1) common share without par value in
the capital stock of the Corporation as constituted on the Effective Date or, in the event of an adjustment contemplated by Section 3.5
of this Plan, such other shares or securities to which an Option Holder may be entitled upon the due exercise of an Option as a result
of such adjustment.

		(gg)	"Subsidiary" means a subsidiary as defined in the QBCA.

		(hh)	"Termination Date" means:

		(i)	in the case of the resignation of the Option Holder as an Employee of the
Corporation, the date that the Option Holder provides notice of his or her resignation as an Employee of the Corporation to the Corporation;

		(ii)	in the case of the termination of the Option Holder as an Employee of the
Corporation by the Corporation for any reason other than death, the effective date of termination set out in the Corporation's notice
of termination of the Option Holder as an Employee of the Corporation to the Option Holder; 

     

    	 	-5-	 

    
		(iii)	in the case of the termination of the written contract of the Option Holder
to provide consulting services to the Corporation, the effective date of termination set out in any notice provided by one of the parties
to the written contract to the other party; or

		(iv)	the effective date of termination of a Director, Employee or Consultant
pursuant to an order made by any Regulatory Authority having jurisdiction to so order.

		(ii)	“U.S.
                                            Taxpayer” has the meaning given in Section 7.1 of this Plan. 

1.2                                     
Choice of Law. This Plan is established under and the provisions of this Plan will be subject
to and interpreted and construed in accordance with the laws of the Province of Québec.

1.3                                     
Headings. The headings used herein are for convenience only and are not to affect the interpretation
of this Plan.

Article 2

PURPOSE AND ADMINISTRATION

2.1                                     
Purpose. The purpose of this Plan is to provide the Corporation with a share-related mechanism
to attract, retain and motivate qualified Directors, Employees and Consultants of the Corporation, and any Subsidiary of the Corporation,
to reward such of those Directors, Employees and Consultants as may be granted Options under this Plan by the Board from time to time
for their contributions toward the long term goals and success of the Corporation and to enable and encourage such Directors, Employees
and Consultants to acquire Shares as long term investments and proprietary interests in the Corporation. 

2.2                                     
Administration. This Plan will be administered by the Board. The Board may make, amend and repeal
at any time and from time to time such regulations not inconsistent with this Plan as it may deem necessary or advisable for the proper
administration and operation of this Plan and such regulations will form part of this Plan. The Board may delegate to any director or
other senior officer or employee of the Corporation such administrative duties and powers as it may see fit.

2.3                                     
Board Powers. The Board shall have the power, where consistent with the general purpose and intent
of this Plan and subject to the specific provisions of this Plan to, amongst other things:

		(a)	establish policies and to adopt rules and regulations for carrying out the
purposes, provisions and administration of this Plan;

		(b)	interpret and construe this Plan and to determine all questions arising
out of this Plan or any Option, and any such interpretation, construction or determination made by the Board shall be final, binding and
conclusive for all purposes;

		(c)	determine the number of Shares reserved for issuance by each Option;

		(d)	determine the Exercise Price of each Option;

		(e)	determine the time or times when Options will be granted and exercisable;

     

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		(f)	determine if the Shares which are issuable on the due exercise of an Option
will be subject to any restrictions upon the due exercise of such Option; and

		(g)	prescribe the form of the instruments and certificates relating to the grant,
exercise and other terms of Options.

2.4                                     
Board Discretion. The Board may, in its discretion, require as conditions to the grant or exercise
of any Option that the Option Holder shall have:

		(a)	represented, warranted and agreed in form and substance satisfactory to
the Corporation that the Option Holder is acquiring and will acquire such Option and the Shares to be issued upon the exercise thereof
for his, her or its own account, for investment and not with a view to or in connection with any distribution, that the Option Holder
has had access to such information as is necessary to enable him, her or it to evaluate the merits and risks of such investment and that
the Option Holder is able to bear the economic risk of holding such Shares for an indefinite period;

		(b)	agreed to restrictions on transfer in form and substance satisfactory to
the Corporation and to an endorsement on any option agreement or certificate representing the Shares making appropriate reference to such
restrictions; and

		(c)	agreed to indemnify the Corporation in connection with the foregoing.

2.5                                     
Board Requirements. Any Option granted under this Plan shall be subject to the requirement that,
if at any time counsel to the Corporation shall determine that the listing, registration or qualification of the Shares issuable upon
due exercise of such Option upon any securities exchange or under any Securities Laws of any jurisdiction, or the consent or approval
of Regulatory Authority, is necessary as a condition of, or in connection with, the grant or exercise of such Option or the issuance or
purchase of Shares thereunder, such Option may not be accepted or exercised in whole or in part unless such listing, registration, qualification,
consent or approval shall have been effected or obtained on conditions acceptable to the Board. Nothing herein shall be deemed to require
the Corporation to apply for or to obtain such listing, registration, qualification, consent or approval.

2.6                                     
Interpretation. The interpretation by the Board of any of the provisions of this Plan and any
determination by it pursuant thereto will be final and conclusive and will not be subject to any dispute by any Option Holder. No member
of the Board or any individual acting pursuant to authority delegated by it hereunder will be liable for any action or determination in
connection with this Plan made or taken in good faith and each member of the Board and each such individual will be entitled to indemnification
with respect to any such action or determination in the manner provided for by the Corporation.

Article 3

GRANT OF OPTIONS

3.1                                     
Board to Issue Shares. The Shares to be issued to Option Holders upon the exercise of Options
will be previously authorized but unissued Shares in the capital stock of the Corporation.

3.2                                     
Participation. The Board will, from time to time and in its sole discretion, determine (i) those
Directors, Employees, Consultants (and, when applicable, to a Company wholly owned by any such Director, Employee or Consultant), if any,
to whom Options are to be granted based upon certain participation criteria, which criteria include but are not limited to functions within
the Corporation, or any Subsidiary of the Corporation, seniority or actual and future contributions to the success of to the Corporation,
or any Subsidiary of the Corporation, and (ii) the number of Options to be granted to such Directors, Employees or Consultants. The Board
may only grant options to an Employee or Consultant if such Employee or Consultant is a bona fide Employee or Consultant of the
Corporation or a Subsidiary of the Corporation, as the case may be. The Board may, in its sole discretion, grant the majority of the Options
to Insiders of the Corporation. However, in no case will the grant of Options under this Plan, together with any proposed or previously
existing security based compensation arrangement, result in (in each case, as determined on the Grant Date):

     

    	 	-7-	 

    

		(a)	the grant to any one Consultant
                                            of the Corporation, or any Subsidiary of the Corporation, within any twelve (12) month period,
                                            of Options reserving for issuance a number of Shares exceeding in the aggregate two percent
                                            (2%) of the Corporation’s issued and outstanding Shares (on a non-diluted basis); or

		(b)	the
                                            grant, within any twelve (12) month period, to all Directors, Employees and/or Consultants
                                            of the Corporation (or any Subsidiary of the Corporation) conducting investor relations services,
                                            of Options reserving for issuance a number of Shares exceeding in the aggregate two percent
                                            (2%) of the Corporation’s issued and outstanding Shares (on a non-diluted basis), calculated
                                            at the date an option is granted to any such Person.

3.3                                     
Number of Shares Reserved. Subject to adjustment as provided for in Section 3.4 of this Plan
and any subsequent amendment to this Plan, the number of Shares reserved for issuance and which will be available for purchase pursuant
to Options granted under this Plan, together with any proposed or previously existing security based compensation arrangement, will equal
to 14,533,881, representing 15% of the issued and outstanding Shares of the Corporation as of August 26, 2020. Subject to the provisions
and restrictions of this Plan, if any Option is cancelled, expired or otherwise terminated for any reason whatsoever, the number of Shares
in respect of which Option is cancelled, expired or otherwise terminated for any reason whatsoever, as the case may be, will ipso facto
again be immediately available for purchase pursuant to Options granted under this Plan. 

3.4                                     
Adjustments. If, prior to the complete exercise of an Option, the Shares are consolidated, subdivided,
converted, exchanged or reclassified or in any way substituted for (collectively, a "Re-Organization Event"), an Option,
to the extent that it has not been exercised, will be adjusted by the Board in accordance with such Re-Organization Event in the manner
the Board deems appropriate and equitable. No fractional Shares will be issued upon the exercise of the Options and accordingly, if as
a result of the Re-Organization Event, an Option Holder would become entitled to a fractional Share, such Option Holder will have the
right to purchase only the next lowest whole number of Shares and no payment or other adjustment will be made with respect to the fractional
interest so disregarded.

3.5                                     
Notification of Grant. Following the approval by the Board of the granting of an Option, the
Board will notify the Option Holder in writing of the award and will enclose with such notice the Option Agreement representing the Option
so granted.

3.6                                     
Copy of Plan. Each Option Holder, concurrently with the notice of the award of the Option, will,
upon written request, be provided with a copy of this Plan, and a copy of any amendment to this Plan will be promptly provided by the
Board to each Option Holder.

3.7                                     
Limitation. This Plan does not give any Option Holder that is a Director the right to serve or
continue to serve as a Director of the Corporation, does not give any Option Holder that is an Employee the right to be or to continue
to be employed by the Corporation and does not give any Option Holder that is a Consultant the right to be or continue to be retained
or engaged by the Corporation as a consultant for the Corporation.

     

    	 	-8-	 

    

Article 4

TERMS AND CONDITIONS OF OPTIONS

4.1                                     
Term of Option. Subject to Section 4.2, the Expiry Date of an Option will be the date so fixed
by the Board at the time the particular Option is granted, provided that such date will be no later than the tenth (10th) anniversary
of the Grant Date of such Option.

4.2                                     
Termination of Option. Subject to such other terms or conditions that may be attached to Options
granted hereunder, an Option Holder may exercise an Option in whole or in part at any time or from time to time during the Exercise Period.
Any Option or part thereof not exercised within the Exercise Period will terminate and become null, void and of no effect as of 5:00 p.m.
(Montréal time) on the Expiry Date. The Expiry Date of an Option will be the earlier of the date so fixed by the Board at
the time the Option is granted and the date established, if applicable, in subsections (a) to (c) below:

		(a)	Death, Disability or Retirement of Option Holder

In the event that the Option Holder should die,
become disabled or retire from the Corporation while he or she is still an Employee (if he or she holds his or her Option as an Employee)
or in the event that the Option Holder should die or become disable while he or she is still a Director (if he or she holds his or her
Option as a Director) or a Consultant (if he or she holds his or her Option as a Consultant), the Expiry Date will be the first anniversary
of the Option Holder's date of death, disability or retirement, as applicable. In addition, in the event that the Option Holder should
die or become disabled, the vesting schedule of such Option Holder’s Option shall automatically accelerate such that there shall
be a full and immediate vesting and entitlement to exercise the relevant Option concurrently with the date upon which such event occurs.

		(b)	Ceasing to Hold Office as Director

In the event that the Option Holder holds his or
her Option as a Director of the Corporation and such Option Holder ceases to be a Director of the Corporation (including by reason of
death or disability) the Expiry Date of the Option will be the first anniversary following the date the Option Holder ceases to be a Director
of the Corporation unless the Option Holder ceases to be a Director of the Corporation as a result of:

		(i)	ceasing to meet the qualifications of a director set forth the QBCA; or

		(ii)	an ordinary resolution having been passed by the shareholders of the Corporation pursuant to the QBCA;
or

		(iii)	an order made by any Regulatory Authority having jurisdiction to so order,

in which case the Expiry Date will be the date the Option Holder ceases
to be a Director of the Corporation.

		(c)	Ceasing to be an Employee or Consultant

In the event that the Option Holder holds his or her Option as an Employee
or Consultant of the Corporation and such Option Holder ceases to be an Employee or Consultant of the Corporation other than by reason
of death, disability or retirement, as applicable in accordance with Section 4.2(a), the Expiry Date of the Option will not exceed the
ninetieth (90th) day following the Termination Date or, if the Employee or Consultant provides investor relations services, the thirtieth
(30th) day following the Termination Date, unless the Option Holder:

     

    	 	-9-	 

    

		(i)	ceases to be an Employee of the Corporation as a result of termination for Cause; or

		(ii)	ceases to be an Employee or Consultant of the Corporation as a result of an order made by any Regulatory
Authority having jurisdiction to so order,

in which case the Expiry Date will be the Termination
Date.

		(d)	Bankruptcy

In the event that an Option Holder commits an act of bankruptcy or any
proceeding is commenced against an Option Holder under the Bankruptcy and Insolvency Act (Canada) or other applicable bankruptcy
or insolvency legislation in force at the time of such bankruptcy or insolvency, the Expiry Date of the Option will be the date immediately
preceding the date on which such Option Holder commits such act of bankruptcy.

Notwithstanding anything contained in this Plan, with
the exception of Section 5.5, in no case will an Option be exercisable after the tenth (10th) anniversary of the Grant Date
of the Option.

4.3                                     
Exercise Price. The price at which an Option Holder may purchase a Share upon the exercise of
an Option (the "Exercise Price") will be determined by the Board and set forth in the Option Agreement issued in respect
of such Option and, in any event, will not be less than the Market Price of the Corporation's Shares calculated as of the Grant Date.
Notwithstanding anything else contained in this Plan, in no case will the Market Price be less than the minimum prescribed by each of
the organized trading facilities as would apply to the Grant Date in question.

4.4                                     
Vesting. Subject to Section 4.2(a), the date or dates on and after which a particular Option,
or part thereof, may be exercised will be determined by the Board and set forth in the Option Agreement issued in respect of such Option;
provided that:

		(a)	all
                                            Options granted to a Director will be vested gradually and evenly over a period of at least
                                            twelve (12) months, on a monthly basis; and

		(b)	all Options granted to an Employee will be vested gradually and evenly over a period of at least thirty-six
(36) months, on a quarterly basis.

4.5                                     
Additional Terms. Subject to all applicable Securities Laws of all applicable Regulatory Authorities,
the Board may attach other terms and conditions to the grant of a particular Option, such terms and conditions to be referred to in the
Option Agreement at the time of grant. These terms and conditions may include, but are not necessarily limited to, the following:

		(c)	providing that an Option expires on a date other than as provided for herein;

		(d)	providing that a portion or portions of an Option vest after certain periods of time or upon the occurrence
of certain events, or expire after certain periods of time or upon the occurrence of certain events;

		(e)	providing that an Option be exercisable immediately, in full, notwithstanding that it has vesting provisions,
upon the occurrence of certain events, such as a friendly or hostile take-over bid for the Corporation; and

     

    	 	-10-	 

    
		(f)	providing that an Option issued to, held by or exercised by an Option Holder who is a citizen or resident
of the United Sates of America, and otherwise meeting the statutory requirements, be treated as an "Incentive Stock Option"
as that term is defined for purposes of the United States of America Internal Revenue Code of 1986, as amended.

4.6                                     
Non-Transferability of Options. The Options granted hereunder are not assignable, transferable
or negotiable (whether by operation of law or otherwise) and may not be assigned or transferred, provided however that the Personal Representative
of an Option Holder may, to the extent permitted by Section 5.1 of this Plan, exercise the Option within the Exercise Period. Upon any
attempt to assign, transfer, negotiate, pledge, hypothecate or otherwise dispose of or transfer an Option contrary to this Section 4.6
of this Plan, or upon the levy of any attachment or similar process upon an Option, the Option and all rights, benefits and privileges
arising thereunder or therefrom, at the sole discretion and election of the Board, shall cease and terminate and be of no further force
or affect whatsoever.

4.7                                     
No Rights as Shareholders. An Option Holder shall not have any rights as a shareholder of the
Corporation with respect to any of the Shares covered by such Option until the date of issuance of a certificate for Shares upon the due
exercise of such Option, in full or in part, and then only with respect to the Shares represented by such certificate or certificates.
Without in any way limiting the generality of the foregoing, no adjustment shall be made for dividends or other rights for which the record
date is prior to the date such share certificate is issued.

Article 5

EXERCISE OF OPTION

5.1                                     
Exercise of Option. An Option may be exercised only by the Option Holder or the Personal Representative
of the Option Holder. Subject to the provisions of this Plan, an Option Holder or the Personal Representative of an Option Holder may
exercise an Option in whole or in part at any time or from time to time during the Exercise Period up to 5:00 p.m. (Montréal time)
on the Expiry Date by delivering to the Secretary of the Corporation an Exercise Notice indicating the number of Shares to be purchased
pursuant to the exercise of the Option, the applicable Option Agreement and a certified cheque or bank draft payable to "Acasti
Pharma Inc." in an amount equal to the aggregate Exercise Price of the Shares to be purchased pursuant to the exercise of the Option.

5.2                                     
Withholding Taxes. In addition to the other conditions on exercise set forth in this Plan, the exercise of each Option granted
under this Plan is subject to the satisfaction of all applicable withholding taxes or other withholding liabilities as the Corporation
may determine to be necessary or desirable in respect of such exercise. The Corporation will require that an Option Holder pay to the
Corporation, in addition to, and in the same manner as, the Exercise Price, such amount as the Corporation is obliged to remit to the
relevant taxing authority in respect of the exercise of the Option.

5.3                                     
Issue of Share Certificates. As soon as practicable following the receipt of (i) the Exercise
Notice and the certified cheque or bank draft referred to in Section 5.1, and (ii) any amounts payable under Section 5.2, the Board will
cause to be delivered to the Option Holder the Shares so purchased in certificated or uncertificated form. If the number of Shares so
purchased is less than the number of Shares subject to the Option Agreement, the Option Holder will surrender the Option Agreement to
the Corporation and the Board will forward a new Option Agreement to the Option Holder concurrently with delivery of the Shares for the
balance of Shares available under the Option.

     

    	 	-11-	 

    

5.4                                     
Condition of Issue. The Options and the issue of Shares by the Corporation pursuant to the exercise
of Options are subject to the terms and conditions of this Plan and compliance with the rules and policies of all applicable Regulatory
Authorities to the granting of such Options and to the issuance and distribution of such Shares, and to all applicable Securities Laws.
The Option Holder agrees to comply with all such laws, regulations, rules and policies and agrees to furnish to the Corporation any information,
reports or undertakings required to comply with and to fully cooperate with the Corporation in complying with such laws, regulations,
rules and policies. Notwithstanding any of the provisions contained in this Plan or in any Option, the Corporation's obligation to issue
Shares to an Option Holder pursuant to the exercise of any Option granted under the Plan shall be subject to:

		(a)	completion of such registration or other qualification of such Shares or
obtaining approval of such Regulatory Authority as the Corporation shall determine to be necessary or advisable in connection with the
authorization, issuance or sale thereof;

		(b)	the admission of such Shares to listing on any stock exchange on which the
Shares may then be listed;

		(c)	the receipt from the Option Holder of such representations, warranties,
agreements and undertakings, as the Corporation determines to be necessary or advisable in order to safeguard against the violation of
the Securities Laws of any jurisdiction; and

		(d)	the satisfaction of any conditions on exercise prescribed pursuant to this
Plan.

5.5                                     
Blackout Period. If an Option expires during, or within five business days after, a trading black-out
period imposed by the Corporation to restrict trades in the Corporation’s securities, then, notwithstanding any other provision
of the Plan, the Option shall expire ten business days after the trading black-out period is lifted by the Corporation, subject to the
maximum period of time during which an Option is exercisable under Sections 7.3 of this Plan.

Article 6

AMENDMENT AND TERMINATION

6.1                                     
Amendment Without Shareholder Approval. Subject to the prior approval of the Exchange, The Board
may amend, suspend or discontinue the Plan, and amend or discontinue any Options granted under the Plan, at any time without shareholder
approval. Without limiting the foregoing, the Board is specifically authorized to amend the terms of the Plan, and the terms of any Options
granted under the Plan, without obtaining shareholder approval, to:

		(a)	amend the vesting provisions to the extent permitted under
the rules and regulations of the Exchange;

		(b)	amend the termination provisions, except as otherwise provided in Section
6.3 (b) hereof;

		(c)	amend the eligibility requirements of eligible Directors, Employees or Consultants
which would have the potential of broadening or increasing Insider participation;

		(d)	add any form of financial assistance;

		(e)	amend a financial assistance provision which is more favorable to Directors,
Employees or Consultants;

     

    	 	-12-	 

    
		(f)	add a deferred or restricted share unit or any other provision which results
in Directors, Employees or Consultants receiving securities while no cash consideration is received by the Corporation; and

		(g)	make other amendments of a housekeeping nature or to comply with the requirements
of any Regulatory Authority.

6.2                                     
Amendment with Shareholder Approval. Notwithstanding Section 6.1, no amendments to the Plan to:

		(a)	increase the number of Shares reserved for issuance under the Plan (including
a change from a fixed maximum number of shares to a fixed maximum percentage of Shares);

		(b)	change the manner of determining the Exercise Price; or

		(c)	amend the amending provisions of Sections 6.1 to 6.3 of this Plan; or

		(d)	change the employees (or class of employees) eligible to receive options
under this Plan

shall be made without obtaining approval of the shareholders in accordance
with the requirements of the Exchange.

6.3                                     
Amendment of Insider Options. Notwithstanding Section 6.1, no amendments to granted Options to:

		(a)	reduce the Exercise Price for the benefit of Insiders; or

		(b)	extend the termination date for the benefit of Insiders, other than in accordance
with Section 5.4 hereof;

shall be made without obtaining approval of the shareholders, or approval
of the disinterested shareholders for amendments under Section 6.3 (a), in accordance with the requirements of the Exchange; and no action
shall be taken with respect to granted Options without the consent of the Option Holder, unless the Board determines that such action
does not materially alter or impair such Option.

6.4                                     
Options Granted Prior to Termination. No amendment, suspension or discontinuance of the Plan
or of any granted Option may contravene the requirements of the Exchange or any securities commission or regulatory body to which the
Plan or the Corporation is now or may hereafter be subject to. Termination of the Plan shall not affect the ability of the Board to exercise
the powers granted to it hereunder with respect to Options granted under the Plan prior to the date of such termination.

6.5                                     
Retrospective Amendment. The Board may from time to time retrospectively amend this Plan and,
with the consent of the affected Option Holders, retrospectively amend the terms and conditions of any Options that have been previously
granted. 

6.6                                     
Change of Control. Notwithstanding anything contained to the contrary in this Plan or in any
resolution of the Board in implementation thereof:

		(a)	in the event of a proposed Change of Control of the Corporation, the Corporation
shall have the right, upon written notice thereof to each Option Holder holding Options under the Plan, to permit the exercise of all
such Options within the twenty (20) day period next following the date of such notice and to determine that upon the expiration of such
twenty (20) day period, all rights of the Option Holders to such Options or to exercise same (to the extent not theretofore exercised)
shall ipso facto terminate and cease to have further force or effect whatsoever;

     

    	 	-13-	 

    
		(b)	in the event of a Change of Control of the Corporation where a notice by
the Corporation was not sent to Option Holders in accordance with Section 6.6(a), 

		(i)	all of the Option Holder’s Options will immediately vest on the date
of such event. In such event, all Options so vested will be exercisable from such date until their respective expiry dates, subject to
the terms of any employment agreement or other contractual arrangement between the Option Holder and the Corporation. For greater certainty,
upon a Change of Control, Option Holders shall not be treated any more favourably than holders of Shares with respect to the consideration
that the Option Holders would be entitled to receive for their Shares; and

		(ii)	if the Option Holder elects to exercise its Options following a Change of
Control, such Option Holder shall be entitled to receive, and shall accept, in lieu of the number of Shares which such Option Holder was
entitled upon such exercise, the kind and amount of shares and other securities, property or cash which such Option Holder could have
been entitled to receive as a result of such Change of Control, on the effective date thereof, had such Option Holder been the registered
holder of the number of Shares to which such Option Holder was entitled to purchase upon exercise of such Options.

6.7                                     
Extension of Expiration Date, Non-Applicability of Termination of Employment Provisions. Subject
to the rules of any relevant Regulatory Authority and Securities Laws, the Board may, by resolution:

		(a)	extend the Expiration Date of any Option, but shall not, in the event of
any such advancement or extension, be under any obligation to advance or extend the date on or by which Options may be exercised by any
other Option Holder; and

		(b)	decide that any of the provisions hereof concerning the effect of termination
of the Option Holder's employment shall not apply to any Option Holder for any reason acceptable to the Board.

Notwithstanding the provisions of Sections 6.6 and
6.7, should changes be required to the Plan by any Regulatory Authority of any jurisdiction to which this Plan or the Corporation now
is or hereafter becomes subject, such changes shall be made to the Plan as are necessary to conform with such requirements and, if such
changes are approved by the Board, the Plan, as amended, shall be filed with the records of the Corporation and shall remain in full
force and effect in its amended form as of and from the date of its adoption by the Board.

6.8                                     
Regulatory Authority Approval. This Plan and any amendments hereto are subject to all necessary
approvals of the applicable Regulatory Authorities.

6.9                                     
Agreement. The Corporation and every Option granted hereunder will be bound by and subject to
the terms and conditions of this Plan. By accepting an Option granted hereunder, the Option Holder has expressly agreed with the Corporation
to be bound by the terms and conditions of this Plan.

     

    	 	-14-	 

    

6.10                                 
Effective Date of Plan. Upon approval by the shareholders of the Corporation in accordance with
the QBCA, and by acceptance by the Exchange (if the Shares are listed or posted on an Exchange and such acceptance is required), the amendments
to this Plan made on May 11, 2016 shall be deemed to be effective as of the Effective Date. Any Options granted prior to such approval
and acceptance(s), that exceed the previous number of Options available for grant, shall be conditional upon such approval and acceptance(s)
being given and no such Options may be exercised unless such approval and acceptance is given.

6.11                                 
Governing Law. This Plan and all matters to which reference is made herein shall be governed
by and interpreted in accordance with the laws of the Province of Québec and the federal laws of Canada applicable therein.

Article 7

U.S. TAXPAYERS

7.1                                     
Provisions for U.S. Taxpayers. Options granted under this Plan to U.S. Taxpayers may be nonqualified
stock options or incentive stock options intended to qualify under Section 422 (“ISOs”) of the United States Internal
Revenue Code of 1986 and the applicable authority thereunder (the “Code”). Each Option shall be designated in the Option
Agreement as either an ISO or a non-qualified stock option. “U.S. Taxpayer” means a Person who is a U.S. citizen, U.S.
permanent resident or U.S. tax resident for the purposes of the Code whose purchase of Shares under this Plan would be subject to U.S.
taxation under the Code. Such Person shall be considered a U.S. Taxpayer solely with respect to such options. Options may be granted as
ISOs only to individuals who are employees of the Corporation or any present or future “subsidiary corporation” or “parent
corporation” as those terms are defined in Section 424(e) and (f) of the Code, and shall not be granted to non-employee Directors
or independent contractors. If an Option Holder ceases to be employed by the Corporation and/or all “subsidiary corporations”
or “parent corporations” as those terms are defined in Section 424(e) and (f) of the Code, other than by reason of death or
disability (meaning “permanent and total disability” as defined in Section 22(e)(3) of the Code), Options shall be eligible
for treatment as ISOs only if exercised no later than three months following such termination of employment.

7.2                                     
ISOs. The maximum number of Options that may be granted as ISOs is equal to the maximum
number of Shares issuable under Section 3.3. The terms and conditions of any ISOs granted hereunder, including the eligible recipients
of ISOs, shall be subject to the provisions of Section 422 of the Code, and the terms, conditions, limitations and administrative procedures
established by the Board from time to time in accordance with this Plan. At the discretion of the Board, ISOs may be granted to any Employee
of the Corporation, its “parent corporation” or any “subsidiary corporation”of the Corporation, as such terms
are defined in Sections 424(e) and (f) of the Code.

7.3                                     
ISO Grants to 10% Shareholders. Notwithstanding anything to the contrary in
this Plan, if an ISO is granted to a Person who owns shares representing more than ten percent of the voting power of all classes of shares
of the Corporation or of a “subsidiary corporation” or “parent corporation”, as such terms are defined in Section
424(e) and (f) of the Code, the term of the Option shall not exceed five years from the time of grant of such Option and the Exercise
Price shall be at least 110 percent (110%) of the Market Price (at the time of grant) of the Shares subject to the Option.

7.4                                     
$100,000 Per Year Limitation for ISOs. To the extent the aggregate Market Price (determined
at the time of grant) of the Shares for which ISOs are exercisable for the first time by any Person during any calendar year (under all
plans of the Corporation) exceeds $100,000, such excess ISOs shall be treated as nonqualified stock options.

     

    	 	-15-	 

    

7.5                                     
Disqualifying Dispositions.Each Person awarded an ISO under this Plan shall notify
the Corporation in writing immediately after the date he or she makes a disqualifying disposition of any Shares acquired pursuant to the
exercise of such ISO. A disqualifying disposition is any disposition (including any sale) of Shares before the later of (i) two years
after the time of grant of the ISO or (ii) one year after the date the Person acquired the Shares by exercising the ISO. The Corporation
may, if determined by the Board and in accordance with procedures established by it, retain possession of any Shares acquired pursuant
to the exercise of an ISO as agent for the applicable Person until the end of the period described in the preceding sentence, subject
to complying with any instructions from such Person as to the sale of such Share.

7.6                                     
Section 409A. Any Options granted to U.S. Taxpayers shall be limited to Employees
or Consultants providing services to the Corporation or to an affiliate which is an “eligible issuer”, as defined in final
Treas. Reg. 1.409A-1(b)(iii) (this includes corporate subsidiaries in which the Corporation has a controlling interest).

		(a)	No extension of term of an Option shall extend beyond the latest date that
the right could have expired by its original terms.

		(b)	Any replacement options issued under Section 3.5 or 6.6 of this Plan shall
comply with U.S. Treas. Reg. 1.424-1 as if the Option were a incentive stock option (ISO) so that the ratio of the Exercise Price to the
fair market value of Shares subject to the Options immediately after the replacement may not be greater than the ratio of the Exercise
Price to the fair market value of Shares subject to the Options immediately before the replacement.

7.7                                     
Transferability.Notwithstanding any other provision in this Plan, an ISO is not transferable except by will or
by the laws of descent and distribution, and may be exercised, during the Option Holder’s lifetime, only by such Option Holder.

Adopted by the Board on October 8, 2008, as amended on April 29, 2009,
March 1, 2011, May 22, 2013, October 5, 2015, May 11, 2016, June 8, 2017, July 27, 2018, April 15, 2019, March 31, 2020 and August 27,
2020 and last approved by the shareholders on September 30, 2020.Exhibit 10.6

 

 

 

 

 

 

INDEPENDENT CONTRACTOR
AGREEMENT

 

THIS INDEPENDENT
CONTRACTOR AGREEMENT (the "Agreement") 1s made
September 14, 2020 (the "Effective Date").

 

BETWEEN:

 

ACASTI PHARMA INC.

 

(the "Company")

 

- and-

 

PFC BUSINESS ADVISORY SERVICES
INC.

 

(the "Contractor")

 

(collectively referred to as the "Parties")

 

WHEREAS the Company wishes to retain the
Contractor as an independent contractor to provide certain services to the Company, on the terms and conditions set forth in this Agreement.

 

THEREFORE ,
the Parties agree as follows:

 

		1.	TERM OF AGREEMENT

 

		(a)	The term of this Agreement shall be for the period commencing on the Effective
Date and continuing until March 14, 2021 unless terminated earlier in accordance with the provisions contained herein. Upon the mutual
agreement of the Parties, the term may be extended for one or more additional three (3)-month periods. Reference to "term"
in this Agreement shall include any mutually agreed period of renewal or extension.

 

		(b)	This Agreement may be terminated at any time and for any reason during this period
by:

 

		(i)	the Contractor providing the Company with 90 days prior written.notice; or

 

		(ii)	the Company providing the Contractor with 90 days prior written notice (the

"Company Notice Period").

 

		(c)	The Contractor agrees and acknowledges that: (i) instead of providing the Company
Notice Period, the Company may, in its sole discretion, elect to pay to the Contractor the Fees that would have been payable during the
Company Notice Period; and (ii) the Company Notice Period shall be in full satisfaction of all entitlements to notice of termination or
severance pay that the Contractor may have under common law, civil law or contract. In the event that it is determined that the Company
Notice Period is less than the notice of termination, severance pay,

 

 

     

     

    

benefits
and other entitlements required to be provided to the Contractor (or the Designee) under any applicable legislation, including employment
standards legislation if it is determined that such legislation applies to the Contractor (or the Designee) (all such legislation, "Applicable
Legislation"), then only the applicable minimum requirements under Applicable Legislation will apply, and any common law or civil
law notice will not apply.

 

		(d)	Notwithstanding Section ](b)(ii), the Company may tenninate this Agreement at
any time without prior notice, for fraud, dishonesty, wilful neglect, misconduct, or any material breach of the terms hereof by the Contractor,
subject only to the Company fully complying with any applicable minimum requirements under Applicable Legislation.

 

		(e)	Subject only to the Company fully complying with any applicable minimum requirements
under Applicable Legislation, upon termination of this Agreement for any reason whatsoever:

 

		(i)	the Contractor shall have no further claims against the Company for damages of
any nature whatsoever under common law, civil law or contract; and

 

		(ii)	the Company shall only be responsible for the payment of;

 

		A.	any reasonable pre-approved expenditures properly incurred by the Contractor under
this Agreement up to the effective date of termination; and

 

		B.	for payment of any Fees accrued under this Agreement up to the effective date
of termination or payment in lieu of Fees; and

 

		(iii)	the Contractor shall be under a duty to mitigate all damages that the Contractor
may claim or assert an entitlement to in respect of the termination of this Agreement.

 

		(f)	Sections 5, 7 and 8 shall survive the termination or expiration of this Agreement
and shall remain binding upon the Contractor.

 

		2.	SERVICES TO BE PROVIDED

 

		(a)	The Company hereby retains the Contractor to perform those services set out in
Schedule A of this Agreement and such other tasks as shall be assigned to the Contractor by the Company or any designee of the Company
at any time and from time to time (collectively, the "Services").

 

		(b)	The Company grants the Contractor the authority and discretion to do such things
as may be reasonably necessary for the purposes of performing the Services. However, the Contractor shall not have the authority or discretion
to enter into any agreement, contract or understanding that legally binds the Company or otherwise assume, create or incur any obligations
or liabilities on behalf of the Company,

 

     

     

    

except as expressly provided for in this Agreement,
withqut first obtaining the prior written consent of the Company.

 

		(c)	The Contractor shall provide Brian Ford (the "Designee") to render
the Services and the Designee shall render the Services primarily at the Company's offices, and such other places as the Company and the
Contractor may mutually agree; provided, however, that the Designee will be made available by the Contractor to travel from time
to time to such other locations of the Company as may be reasonably necessary in order to discharge the Services. The Parties agree that
during the term the Designee will remain solely the employee of the Contractor and shall not be an employee of the Company. For purposes
of this Agreement, all references to the "Contractor" shall also include and bind the Designee.

 

		3.	FEES AND EXPENSES

 

[n consideration of the Services provided,
the Company shall pay to the Contractor a fee of CON $36,000, plus HST (at a rate if 13%), per month in which Services are rendered (the
"Fee"). Payments will be made concurrently with the Company's payroll practices at $18,000 plus HST per pay period.
The Contractor shall provide the Company with a purchase order confirmation with respect to the Services, such purchase order confirmation
shall clearly reference the Contractor's goods and services tax registration number(s).

 

The Company will reimburse
the Contractor for all necessary and reasonable out-of-pocket expenses directly related to performance of the Services by the Contractor.
Any expenses in excess of$ 1,000 must be pre-approved by the Company (in advance of being incurred). All expenses, to the extent possible,
will be substantiated by original written receipts and submitted for reimbursement within 30 days of being submitted to the Company for
reimbursement.

 

		4.	HOURS OF WORK

 

There shall be no
set hours of work. However, the Contractor agrees to be reasonably available to provide Services to the Company as may be required. The
Contractor acknowledges that there may be special circumstances which will require Services to be provided outside standard working hours
for which no additional compensation will be provided.

 

S.       INDEPENDENT CONTRACTOR

 

The Contractor
is and shall remain at all times an independent contractor and is not, and shall not represent the Contractor or Designee to be an agent,
joint venturer, partner, director or employee of the Company. Nothing contained in this Agreement is intended to create nor shall be construed
as creating an employment relationship between the Contractor (or the Designee) and the Company.
The Contractor has sole responsibility, as an independent contractor, to comply with all laws, rules and
regulations relating to the provision of Services, including without limitation, requirements under the Income Tax Act (Canada),
the Employment Insurance Act (Canada), and the Canada Pension Plan Act. As an independent contractor, the Consultant shall
not be entitled to any employment related benefits, including without limitation, any payments under the Employment Standards Act (Ontario)
or the equivalent legislation in the Province of Quebec. The Contractor shall be responsible for deducting any and all applicable federal
and provincial taxes, deductions, premiums, and amounts owing with respect to those Fees paid by the Company. The

 

     

     

    

Contractor further
agrees to indemnify and hold the Company, its directors, officers, agents and employees harmless from and against any and all liabilities,
claims, demands, suits, losses, fines, surcharges, damages, costs and expenses in respect of any failure on the part of the Company to
(i) withhold any taxes, premiums, payments, benefit overpayments, levies or other amounts from all or any part of the Fees or other amounts
paid to the Contractor during the term of this Agreement; or (ii) comply with requirements to make
payments under Applicable Legislation.

 

		6.	CONFLICT OF INTEREST

 

The Contractor agrees
that, during the term of this Agreement, the Contractor will not, without the prior written consent of the Company, engage in, accept
employment from, perform services for, or become affiliated with or connected with, either directly or indirectly, any person, firm, corporation,
partnership or other business entity which is doing business with the Company relative to any project worked on by the Contractor under
this Agreement, and further agrees that the Contractor will avoid all circumstances and actions which would place the Contractor in a
position of divided loyalty with respect to the Contractor's obligations in connection with this Agreement.

 

		7.	CONFIDENTIALITY OF INFORMATION AND OWNERSIDP
                                                                                                    OF PROPRIETARY PROPERTY

 

Upon execution and delivery
of this Agreement, the Contractor shall execute and deliver the Confidentiality of Information and Ownership of Proprietary Property Agreement,
attached in Schedule B of this Agreement.

 

		8.	HEALTH AND SAFETY, DAMAGE TO PROPERTY

 

The Contractor shall
comply with applicable health and safety laws, and hereby agrees to indemnify and hold harmless the Company, its directors, officers,
agents and employees from and against any and all claims, demands, suits, losses, fines, surcharges, damages, costs and expenses arising
out of the Contractor's failure to comply with such laws. The Contractor further agrees to indemnify and hold the Company, its directors,
officers, agents and employees harmless from and against any and all liabilities, claims, demands, suits, losses, fines, surcharges, damages,
costs and expenses relating to the injury or death of any person, damage to or destruction of any property, which is directly or indirectly
caused by any act or omission on the part of the Contractor or any employees of the Contractor engaged in providing Services to the Company.

 

		9.	SEVERABILITY

 

In the
event that any covenant, provision or restriction contained in this Agreement is found to be void or unenforceable (in whole or in part)
by a court of competent jurisdiction, it shall not affect or impair the validity of any other covenant, provisions or restrictions contained
herein, nor shall it affect the validity or enforceability of such covenants, provisions or
restrictions in any other jurisdiction or in regard to other circumstances . Any
covenants, provisions or restrictions found to be void or unenforceable are declared to be separate and distinct, and the remaining covenants,
provisions and restrictions shall remain in full force and effect.

 

     

     

    

		10.	PROTECTION OF COMPANY INTERESTS

 

		10.1	Non-Competition/Non-Solicitation

 

The Consultant will
not, either while providing Services to the Company or for a period of one (1) year subsequent to the termination or expiration of this
Agreement, for any reason, without the Company's prior written consent, either as an individual, or in conjunction with any other person,
finn, corporation, or other entity, whether acting as a principal, agent, employee, consultant, or in any capacity whatsoever:

 

		(a)	engage in or in any way be concerned with any business or enterprise relating
to the business of the Company within the territory of Canada and the U.S.;

 

		(b)	solicit, attempt to solicit, call upon, or accept the business of any finn, person
or company who is or was a customer, client, supplier or distributor of the Company;

 

		(c)	take advantage of, derive a benefit or otherwise profit from any business opportunities
that the Consultant became aware of in the course of providing Services to the Company even if the Company does not take advantage of
or exploit such opportunities;

 

		(d)	take any action as a result of which relations between the Company and its customers,
clients, suppliers, distributors, employees or others may be impaired or which might otherwise be detrimental to the business interests
or reputation of the Company;

 

		(e)	solicit, attempt to solicit, or communicate in any way with any employees or consultants
of the Company for the purpose of having such employees or consultants employed or in any way engaged by another person, firm, corporation,
or other entity; or

 

(t)
hire, whether as an employee, consultant or otherwise, any person who, either at the time the Consultant is
providing Services to the Company, or who at any time within the preceding twelve month period was
employed or engaged by the Company.

 

		10.2	Vital Consideration

 

The Consultant agrees
that the covenants and restrictions contained in the preceding paragraph are reasonable and valid in terms of time, scope of activities
and geographical limitations and understands and agrees that they are vital consideration for the purposes of the Company entering into
this Agreement.

 

		10.3	Interpretation

 

For purposes of this
Article I 0, all references to the "Company" shall include the Company and its affiliates.

 

 

		11.	CHANGES TO AGREEMENT

 

     

     

    

Any modifications
or amendments to this Agreement must be in writing and signed by both Parties or else they shall have no force and effect. The Parties
specifically acknowledge that the Company's continued retention of the Contractor shall be sufficient and ample consideration supporting
any future modifications or amendments to this Agreement.

 

		12.	ENUREMENT

 

This Agreement shall
enure to the benefit of and be binding upon the Parties and their respective successors and assigns, including without limitation, the
Contractor's heirs, executors, administrators and personal representatives.

 

		13.	ASSIGNMENT

 

The
Contractor may not assign any of the Contractor's rights or delegate any of the Contractor's duties or responsibilities
under this Agreement, without the Company's prior written consent. The Company may, without the consent
of the Contractor, assign its rights, duties and obligations under this Agreement to an affiliate or to a purchaser of all, or substantially
all of the assets of the Company.

 

		14.	ENTIRE AGREEMENT

 

This Agreement constitutes
the entire agreement between the Parties and supersedes and replaces any and all other representations, understandings, negotiations and
previous agreements, written or oral, express or implied.

 

		15.	LEGAL ADVICE

 

The Contractor acknowledges
that the Contractor has read and understands the terms and conditions contained in this Agreement, and that the Company has provided a
reasonable opportunity for the Contractor to seek independent legal advice prior to executing this Agreement.

 

		16.	CURRENCY

 

All dollar amounts set forth or referred to in
this Agreement refer to Canadian currency.

 

		17.	NOTICES

 

		17.1	Notice to Contractor

 

Any notice required
or permitted to be given to the Contractor shall be deemed to have been received if delivered personally to the Contractor, sent to (contractor
address], or if mailed by registered mail to the Contractor's business address last known to the Company.

 

		17.2	Notice to Company

 

Any notice required
or permitted to be given to the Company shall be deemed to have been received if delivered personally to, mailed by registered mail, or
sent to 3009 boul. de la Concorde E., Suite I 02, Laval, Quebec, H7E 2B5, addressed to the attention of the Chief Executive Officer.

 

     

     

    

		18.	GOVERNING LAW

 

This Agreement shall
be interpreted and construed in accordance with the laws of the Province of Quebec and the laws of Canada applicable therein.

 

		19.	LANGUAGE

 

The parties hereto
have expressly required that this agreement and documents ancillary thereto be drafted in the English language. Les parties a
la presente ont expressement exige que le present accord et Jes documents qfferents soient rediges en langue anglaise.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

     

     

    

IN WITNESS OF WHICH the Parties
have duly executed this Agreement:

 

 

	 	ACASTI PHARMA INC.

                                                   

                                                   

	 	/s/ Janelle D’Alvise
	 	
    Name: Jan D’Alvise

    Title: President and CEO

	 	 

 

 

 

 

 

 

 

PFC BUSINESS ADVISORY SERVICES

INC.

 

By:

/s/ Brian Ford                                                       

Name: Brian Ford

Title: Authorized Signatory

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Signature Page to Independent Contractor
Agreement

 

     

     

    

SCHEDULE A

 

SERVICES TO BE PROVIDED

 

All such services
and duties for the Company comparable to those performed by a Chief Financial Officer of a public company in a similar industry and at
a comparable stage of development as the Company.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

     

     

    

SCHEDULE B

 

CONFIDENTIALITY
OF INFORMATION

AND OWNERSHIP OF PROPRIETARY PROPERTY
AGREEMENT

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

     

     

    

AMENDMENT TO INDEPENDENT CONTRACTOR AGREEMENT

 

THIS AMENDMENT TO INDEPENDENT CONTRACTOR AGREEMENT is
made effective as of March 15, 2021.

 

BETWEEN:

ACASTI PHARMA INC.

 

(the "Company")

 

-and-

 

PFC BUSINESS ADVISORY SERVICES INC.

 

(the "Contractor")

 

(collectively referred to as the "Parties")

 

WHEREAS the Company and the
Contractor are parties to an independent contractor agreement dated September 14, 2020 (the "Contractor Agreement").

 

AND WHEREAS The Contractor and the Company wish
to mutually amend the Contractor Agreement in order to extend the term of the Contractor Agreement in accordance with the terms and conditions
of this amendment (the "Amendment").

 

THEREFORE, for good and sufficient consideration, the
Parties agree as follows

 

		1.	Pursuant to section l(a) of the Contractor Agreement, the term of the Contractor
Agreement shall be extended for an additional three (3) months from March 15, 2020 to June 14, 2021, unless terminated earlier in accordance
with the provisions contained in the Contractor Agreement. Reference to "term" in the Contractor Agreement shall include
any mutually agreed period of renewal or extension, including the extension by virtue of this Amendment.

 

		2.	Except as otherwise provided in this Amendment, all terms and conditions of the
Contractor Agreement shall continue in full force and effect.

 

		3.	This Amendment shall be interpreted and construed in accordance with the laws of
the Province of Quebec and the laws of Canada applicable therein.

 

		4.	This Amendment may be executed in counterparts and delivered by means of facsimile
or portable document format (PDF), each of which when so executed and delivered shall be an original, but all such counterparts together
shall constitute one and the same instrument.

 

 

 

 

 

 

     

     

    

IN WITNESS OF WHICH the Parties have duly executed this
Amendment:

 

	 	ACASTI PHARMA INC.

                                                   

                                                   

                                                   

	 	/s/ Janelle D’Alvise
	 	
    Name: Jan D’Alvise

    Title: President and CEO

	 	 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Signature Pave to Amendment Agreement

 

 

 

     

     

    

PFC BUSINESS ADVISORY SERVICES

INC.

 

By:

/s/ Brian Ford                                                   

Name: Brian Ford

Title: Authorized Signatory

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Signature Page to Amendment Agreement

     

     

    

 

AMENDMENT TO INDEPENDENT CONTRACTOR AGREEMENT

 

THIS AMENDMENT TO INDEPENDENT CONTRACTOR AGREEMENT
is made effective as of June 16, 2021.

 

BETWEEN:

ACASTI PHARMA INC.

 

(the "Company")

 

-and-

 

PFC BUSINESS ADVISORY SERVICES INC.

 

(the "Contractor")

 

(collectively referred to as the "Parties")

 

WHEREAS the Company and the
Contractor are parties to an independent contractor agreement dated September 14, 2020 (the "Contractor Agreement").

 

AND WHEREAS The Contractor and
the Company wish to mutually amend the Contractor Agreement in order to extend the term of the Contractor Agreement in accordance with
the terms and conditions of this amendment (the "Amendment").

 

THEREFORE, for good and sufficient consideration, the
Parties agree as follows

 

		1.	Pursuant to section l(a) of the Contractor Agreement, the term of the Contractor
Agreement shall be extended for an additional three (3) months from June 15, 2020 to September 14, 2021, and will automatically be extended
if needed through the closing of the acquisition of Grace, unless terminated earlier in accordance with the provisions contained in the
Contractor Agreement. Reference to "term" in the Contractor Agreement shall include any mutually agreed period of renewal
or extension, including the extension by virtue of this Amendment.

 

		2.	Except as otherwise provided in this Amendment, all terms and conditions of the
Contractor Agreement shall continue in full force and effect.

 

		3.	This Amendment shall be interpreted and construed in accordance with the laws of
the Province of Quebec and the laws of Canada applicable therein.

		4.	This Amendment may be executed in counterparts and delivered by means of facsimile
or portable document format (PDF), each of which when so executed and delivered shall be an original, but all such counterparts together
shall constitute one and the same instrument.

 

 

 

 

 

     

     

    

IN WITNESS OF
WHICH the Parties have duly executed this
Amendment:

 

 

 

 

 

	 	ACASTI PHARMA INC.

                                                   

                                                   

	 	/s/ Janelle D’Alvise
	 	
    Name: Jan D’Alvise

    Title: President and CEO

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Signature page
to Amendment Agreement

 

     

     

    

 

PFC BUSINESS ADVISORY SERVICES

INC.

 

By:

/s/ Brian Ford                                                 

Name: Brian Ford

Title: Authorized Signatory

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Signature Page to Amendment Agreement

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