Document:

EX-10.6

 Exhibit 10.6 

Mandate Agreement 

between 
 Auris Medical
AG, Basel 
 and 

Altamira Pharma GmbH, Zuchwil 
 Mandate

 Auris Medical AG (“AMAG”) herewith instructs and mandates Altamira Pharma GmbH (“APG”) to provide support to AMAG in the strategic
management of the business and in selected operational tasks. 
 Fees 

AMAG shall pay to APG a monthly fee of CHF 20’000.—, including VAT, and a lump-sum expense allowance of CHF 600.—. Expenses in excess of the
lump-sum allowance incurred in relation with the execution of the mandate shall be charged separately and against receipt. 
 Confidentiality 

APG shall maintain secrecy over any and all business secrets and confidential information supplied based upon this agreement or of which it has obtained
knowledge otherwise. This confidentiality obligation shall apply for the duration of this mandate and three years after its termination. 
 No
confidentiality obligation shall apply if and to the extent that information concerned 
  

	•	 	is in the public domain, or 

  

	•	 	has become of public domain without act or failure of the concerned contractual party, or 

  

	•	 	was / has been obtained rightfully by a third party, or 

  

	•	 	already was in possession of the concerned contractual party. 

 Upon termination of this agreement, APG shall
immediately return all documents, files, letters, schemes, equipment, products, software etc. belonging to AMAG, as well as copies and electronic records thereof, to AMAG. 

Non-competition clause 
 During this mandate, APG
undertakes not to perform any activities which are directly or indirectly competing with AMAG. 

  
 1 

 Intellectual Property Rights 

Inventions, creations, works and other Intellectual property are owned by AMAG to the extent as they are created in the performance of APG’s contractual
obligations. 
 Duration of the Mandate 
 This mandate
is entered into for an indefinite period of time. Either party may terminate the agreement in writing with a 3-months’ notice period, with effect as to the end of a month. 

Miscellaneous 
  

	•	 	If any provision of this agreement is held to be invalid, such invalidity shall not affect any other part of this contract. 

  

	•	 	The place of jurisdiction is the City of Basle. 

  

			
	Basle, 4 January 2011	  	Zuchwil, 4 January 2011
		
	[Signature]	  	[Signature]
		
	Auris Medical AG	  	Altamira Pharma GmbH

  
 Page 2EX-10.7

 Exhibit 10.7 

EXECUTION VERSION 
 SERVICE
TERMINATION AGREEMENT 
 (hereinafter referred to as the/this “Agreement”) 

between 
 Auris Medical AG, Falknerstrasse
4, 4001 Basel 
 (hereinafter referred to as “Auris”), 

and 
 Altamira Pharma GmbH, Birkenweg 6,
4528 Zuchwil 
 (hereinafter referred to as “Altamira”) 

(Auris and Altamira both referred to as “Parties”) 

WHEREAS: 
  

	 	•	 	the Parties have entered into a service agreement / “Mandatsvereinbarung” dated as of 4 January 2011 (hereinafter referred to as “Service Agreement”); 

 

	 	•	 	under the Service Agreement Altamira has been rendering strategic management services and supported in selected operational tasks to Auris; 

 

	 	•	 	the Parties wish to terminate the Service Agreement by way of mutual agreement with effect as of 31 January 2014; 

Therefore, the Parties agree as follows: 
  

	1.	Termination of Service Agreement 

 The Parties mutually state and agree that the Service Agreement has
ended with effect as of 31 January 2014. Accordingly, the Parties mutually waive the termination period as set out in the Service Agreement. 

  

			
	434580	  	Page 1 of 3

 EXECUTION VERSION 
  

	2.	Final payment 

 Auris agrees to make a final payment in the amount of CHF 14’500 (hereinafter
referred to as “Final Payment”). The Final Payment shall be in full settlement of any and all claims of Altamira out of or in connection with the services rendered under the Service Agreement until 31 January 2014. The Final
Payment shall be inclusive of all costs, expenses and taxes. 
  

	3.	Final Settlement and Waiver 

 The Parties agree that with the execution of this Agreement, any and all
mutual claims out of the Service Agreement or termination of the Service Agreement between the Parties shall have been fully and finally settled, with exception of the obligations of Altamira concerning confidentiality (“Vertraulichkeit”)
and intellectual property rights (“Rechte an immateriellen Gütern”). 
  

	4.	Miscellaneous 

 Should any provision of this Agreement be deemed or held to be wholly or partially
invalid, ineffective or unenforceable, this shall not affect the validity, effectiveness or enforceability of the remainder hereof. The Parties hereby agree to replace any provision so severed by a provision, negotiated in good faith that achieves
as closely as possible the original intention of the parties. 
 This Agreement (including this clause) may only be amended if the Parties confirm such
amendment in writing. 
 This Agreement shall be exclusively interpreted, supplemented and governed by Swiss Law (Code of Obligations). 

 

									
	Place, Date:	 	

	 		 	Place, Date:	 	

		 	  
	 		 		 	  

			
	Auris Medical AG	 		 	Altamira Pharma GmbH
			
	

	 		 	

	  
	 		 	  

	Oliver Kubli	 	 Wolfgang Arnold
	 		 	Thomas Meyer
	Vice Chairman	 	 Secretary
	 		 	Managing Director

  

			
	434580	  	Page 2 of 3

 EXECUTION VERSION 
  

	2.	Final payment 

 Auris agrees to make a final payment in the amount of CHF 14’500 (hereinafter
referred to as “Final Payment”). The Final Payment shall be in full settlement of any and all claims of Altamira out of or in connection with the services rendered under the Service Agreement until 31 January 2014. The Final
Payment shall be inclusive of all costs, expenses and taxes. 
  

	3.	Final Settlement and Waiver 

 The Parties agree that with the execution of this Agreement, any and all
mutual claims out of the Service Agreement or termination of the Service Agreement between the Parties shall have been fully and finally settled, with exception of the obligations of Altamira concerning confidentiality (“Vertraulichkeit”)
and intellectual property rights (“Rechte an immateriellen Gütern”). 
  

	4.	Miscellaneous 

 Should any provision of this Agreement be deemed or held to be wholly or partially
invalid, ineffective or unenforceable, this shall not affect the validity, effectiveness or enforceability of the remainder hereof. The Parties hereby agree to replace any provision so severed by a provision, negotiated in good faith that achieves
as closely as possible the original intention of the parties. 
 This Agreement (including this clause) may only be amended if the Parties confirm such
amendment in writing. 
 This Agreement shall be exclusively interpreted, supplemented and governed by Swiss Law (Code of Obligations). 

 

									
	Place, Date:	 	

	 		 	Place, Date:	 	
		 	  
	 		 		 	  

			
	Auris Medical AG	 		 	Altamira Pharma GmbH
				
		 	 

	 		 	
	  
	 		 	  

	Oliver Kubli	 	 Wolfgang Arnold
	 		 	Thomas Meyer
	Vice Chairman	 	 Secretary
	 		 	Managing Director

  

			
	434580	  	Page 3 of 3EX-10.8

 Exhibit 10.8 

Loan Agreement 
 between

 Auris Medical AG 
 and

 Altamira Pharma GmbH 
 Altamira Pharma
GmbH, Zuchwil, and Auris Medical AG, Basel (the “Parties”), agree to enter into a loan agreement (“Agreement”) as follows: 
 Altamira
Pharma GmbH (“Lender”) is providing a revolving credit facility of up to CHF 250,000 and up to EUR 250,000 (“Loan Amount”) to Auris Medical AG (“Borrower”), starting January 11, 2013, for a maximum of 30 days at an
annual interest rate of 5%. Lender agrees to transfer Loan Amount upon request either as a whole or in tranches to Borrower’s bank account(s) and Borrower agrees to pay back Loan Amount as well as accrued interest on February 11, 2013 at
the latest to Lender’s bank account(s). 
  

											
	Basel,	 	 9.1.2013
	 		 	Zuchwil,	 	 08.01.2013

				
	Auris Medical AG	 		 		 	Altamira Pharma GmbH
			
	

	 	

	 	

	Oliver Kubli	 	Prof Wolfgang Arnold	 	Dr Thomas Meyer

  
 1/1EX-10.10

 Exhibit 10.10 

English Translation 
 [Letterhead
of Privera AG] 
 Lease Agreement for Commercial Premises 

between 
  

					
	Assetimmo Immobilien Anlagestiftung	  	hereinafter the Landlord	  	
	Badenerstrasse 329	  		  	
	 CH-8003 Zürich
  

represented by
	  		  	
	  
 PRIVERA AG
	  	hereinafter the Representative	  	
	Mühlematt Shopping	  		  	
	 4104 Oberwil
  

and
	  		  	
	  
 Auris Medical AG
	  	hereinafter the Tenant	  	
	Aeschenvorstadt 37	  		  	
	4051 Basel	  		  	

 Concerning the lease of premises in the property 

Falknerstrasse 2/4, CH-4001 Basel 

 Commercial Lease Agreement 
  

 Table of Contents 
  

							
	 1.
	  	 Terms used
	  	 	3	  
			
	 2.
	  	 Lease object
	  	 	3	  
			
	 3.
	  	 Purpose of usage
	  	 	4	  
			
	 4.
	  	 Start of lease, term of lease, option right, extension and termination
	  	 	4	  
			
	 4.1
	  	 Start of lease
	  	 	4	  
			
	 4.2
	  	 Term of lease / termination
	  	 	4	  
			
	 4.3
	  	 Option right
	  	 	4	  
			
	 5.
	  	 Rent and ancillary obligations
	  	 	5	  
			
	 5.1
	  	 Base rent on conclusion of the agreement
	  	 	5	  
			
	 5.2
	  	 Rent adjustments after start of the lease
	  	 	5	  
			
	 5.3
	  	 Rent payments
	  	 	6	  
			
	 5.4
	  	 Ancillary expenses
	  	 	6	  
			
	 5.5
	  	 Interest
	  	 	7	  
			
	 5.6
	  	 Value added tax
	  	 	7	  
			
	 5.7
	  	 Taxes, fees, public charges
	  	 	8	  
			
	 6.
	  	 Fit out and usage of the lease object
	  	 	8	  
			
	 6.1
	  	 Condition and use of the lease object
	  	 	8	  
			
	 6.2
	  	 Handover of keys
	  	 	10	  
			
	 6.3
	  	 Insurance / surveillance
	  	 	10	  
			
	 6.4
	  	 Company signs, advertising, lettering and marketing activities
	  	 	11	  
			
	 6.5
	  	 Parking spaces
	  	 	11	  
			
	 6.6
	  	 Right to inspect
	  	 	11	  
			
	 6.7
	  	 Sublease
	  	 	12	  
			
	 6.8
	  	 Maintenance by the Tenant
	  	 	12	  
			
	 7.
	  	 Return of the lease object
	  	 	13	  
			
	 7.1
	  	 Return upon termination of the lease agreement
	  	 	13	  
			
	 7.2
	  	 Re-instatement of the previous state / duty to dismantle
	  	 	13	  
			
	 8.
	  	 Final provisions
	  	 	13	  
			
	 8.2
	  	 Integrated elements of this agreement
	  	 	14	  
			
	 8.3
	  	 Contract amendments
	  	 	14	  
			
	 8.4
	  	 Duty of disclosure
	  	 	14	  
			
	 8.5
	  	 Severability
	  	 	14	  
			
	 8.6
	  	 Subsidiary law and place of jurisdiction
	  	 	14	  
			
	 8.7
	  	 Copies of the agreement
	  	 	15	  

  
 Initials Landlord
             Initials Tenant              

Page 2/ 15 

 Commercial Lease Agreement 
  

	1.	Terms used 

 Irrespective of the legal form or gender of a party, or the number of people
or legal entities constituting a party, for ease of reference the generic terms “Landlord”, “Representative” and “Tenant” are used in this agreement. 

 

	2.	Lease object 

  

	2.1	Location and surface area 

 The Landlord leases to the Tenant the below identified areas of the
property referred to on the first page above, the location and area of which are outlined in red on the attached floor plan. The condition and composition of the lease object is described in the description of fit out also attached hereto. The
stated surface areas are guidelines and may deviate from the actual surface areas. Any such deviations shall have no impact on the applicable rent or the formula for calculation of ancillary expenses. 

 

																			
	Base rent on conclusion of the agreement	 	  	Annual	 	  	Monthly	 
	Ref. N0.	  	Level Object	  	surface
m2 ca	 	  	CHF/
m2	 	  	 Total

CHF
	 	  	 Total

CHF
	 
	 Net rent 21003.01.430010
	  	3rd floor office	  	 	300.2	  	  	 	275.00	  	  	 	82’555.00	  	  	 	6’880.00	  
		  		  				  				  	  
	  
	 	  	  
	  
	 
		  	 Total
	  				  				  	 	82’555.00	  	  	 	6’880.00	  
						
	 Ancillary expense advance 2100.01.430010
	  	3rd floor office	  	 	300.2	  	  	 	30.00	  	  	 	9’006.00	  	  	 	751.00	  
		  		  				  				  	  
	  
	 	  	  
	  
	 
		  	 Total
	  				  				  	 	9’006.00	  	  	 	751.00	  
		  		  				  				  	  
	  
	 	  	  
	  
	 
	 Gross rent
	  	Total	  				  				  	 	91’561.00	  	  	 	7’631.00	  
		
	 Payable monthly in advance on the first day of the month
	   
	  	 	7’631.00	  

 The amounts are in part rounded up or down for IT reasons. 

 

	2.2	Facades, Roof Areas, Common Areas 

 The right to dispose over walls, facades, roof areas and all
common areas bordering on the rental areas remains exclusively with the Landlord. 

  
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             Initials Tenant              

Page 3/ 15 

 Commercial Lease Agreement 
  

	2.3	Surface area calculation 

 The calculation of surface areas is made from axis to axis, from the
middle of separating walls and subdivisions, or the inner side of common areas. The surface so calculated as stated in this agreement is deemed to have been accepted with binding effect for both parties. 

 

	3.	Purpose of usage 

  

	3.1	Type of use 

 The Tenant is entitled and obliged to use and operate the lease object during the
whole contractual period as follows: office premises. 
  

	3.2	Usage by third parties 

 (see also Section 6.7) 

The Tenant may sublease the lease object in whole or in part (art. 262 of the Code of Obligations) or assign the lease together with all rights
and obligations to a third party (art. 263 of the Code of Obligations) only with the Landlord’s prior written consent. 
  

	4.	Start of lease, term of lease, option right, extension and termination 

  

	4.1	Start of lease 

 The lease commences on 01.04.2013. 

The Tenant rents the lease object in accordance with the description of fit out and the floor plans. Any defects in the lease object will be
recorded in a protocol at the time of handover of the lease object, and the protocol will be signed by both parties. If further defects appear in addition to those recorded in the protocol, the Tenant must give notice of these in writing within 30
days of the handover. In the absence of notice, the Tenant is assumed to have taken over the lease object in a condition suitable for the intended use. 
  

	4.2	Term of lease / termination 

 The lease is concluded for a fixed term (art. 255 para 2 of the
Code of Obligations) and expires without notice on 31.03.2018 – subject to the option right pursuant to Section 4.3 below. The Tenant is granted a one-off unilateral right of termination per 31.03.2016 on giving 12 months’ prior
notice. 
  

	4.3	Option right 

 The Tenant is granted an option right to extend the minimum term of the lease
agreement for a further 1 x 5 years. If it wishes to make use of this right, the Tenant must give notice to the Landlord in writing by registered letter at the latest 12 months prior to the first possible termination date, i.e. by 31.03.2017. 

  
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             Initials Tenant              

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 Commercial Lease Agreement 
  

 To the extent that the Tenant exercises its option right, the Landlord is entitled but not
obliged to adjust the rent for the new contract period in accordance with the then relevant market conditions. If the parties cannot agree on the then applicable rent at the latest by 12 months prior to the first possible termination date, the
declaration of exercise of the option will not result in the extension of the lease agreement and the agreement will terminate on 31.03.2018. 

If the Tenant does not exercise the option right or does not do so on time, the lease terminates on 31.03.2018. 

Any sub-lease or assignment of lease (art. 262 and art. 263 of the Code of Obligations) will have the effect that all option rights still
existing and not exercised at the relevant point of time become ineffective. 
  

	5.	Rent and ancillary obligations 

  

	5.1	Base rent on conclusion of the agreement 

 The annual base rent on conclusion of this agreement
amounts to CHF 82’555.00. 
  

	5.2	Rent adjustments after start of the lease 

  

	5.2.1	General 

 The valid base rent at the start of the lease (see Section 5.1) will be adjusted
annually in line with the National Index of Consumer Prices of the Swiss Federal Statistical Office. 
 Index clause: 100.0% of the
applicable minimum rent at the start of the lease will be adjusted annually in line with the National Index of Consumer Prices in accordance with the following formula. 
  

							
	 base rent x new index
	  	=	  	new rent	  	
	base index	  		  		  	

 The base index is given by the index position of 99.1 points as per 11/2012: (basis December 2010 = 100
points). 
 The first adjustment of the base rent may occur on 01.04.2014. The following rent adjustments may occur once per calendar year on
the first day of any month. 
  

	5.2.2	Value-enhancing investments 

 Value-enhancing investments and additional expenditure by the
Landlord and costs for substantial renovations entitle the Landlord to increase the rent, also during the fixed contract term, by applying an appropriate rate for interest, amortization and maintenance

  
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             Initials Tenant              

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 Commercial Lease Agreement 
  

 
pursuant to the applicable legal provisions for lease contracts. Such adjustments will be notified to the Tenant in the form required by law by giving 3 months’ notice in advance of the
first day of any month. 
  

	5.3	Rent payments 

 The rent must be paid in monthly installments in advance, at the latest on the
first day of each month, for the first time pro rata temporis on the first day of the lease. 
  

	5.4	Ancillary expenses 

  

	5.4.1	General 

 Ancillary expenses are not included in the base rent and must be paid in addition by
the Tenant. An advance on ancillary expenses of CHF 751.00 is due on the first of each month, for the first time pro rata temporis on the first day of the lease. 

Ancillary expenses include: 

Heating and hot water expenses 
  

	 	•	 	Fuels 

  

	 	•	 	Electricity for the operation of burners and pumps 

  

	 	•	 	Cleaning of the heating system, including the oil tank 

  

	 	•	 	Periodical maintenance of the heating system, including the oil tank 

  

	 	•	 	Recordal of usage and the invoicing service for the counter, including servicing 

  

	 	•	 	Servicing of the heating system (salary of employee) 

  

	 	•	 	Invoicing costs (plus VAT) 

 Operating expenses 

 

	 	•	 	Water and waste water 

  

	 	•	 	Electricity 

  

	 	•	 	Caretaker 

  

	 	•	 	Cleaning (incl. windows, facade and snow clearance) 

  

	 	•	 	Antennae and copyright payments 

  

	 	•	 	Invoicing costs (plus VAT) 

  

	 	•	 	All costs related to the use of the lease object, the common and public surfaces and infrastructure for use, cleaning and maintenance of: 

 

	 	•	 	Ventilation and air-conditioning systems 

  
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             Initials Tenant              

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 Commercial Lease Agreement 
  

	 	•	 	Fire alarm systems and fire-fighting equipment 

  

	 	•	 	Burglary and alarm systems 

  

	 	•	 	Escalators, elevators and lifting ramps 

  

	 	•	 	Canalization and pump shafts 

 Shared advertising costs, contributions to the common parts etc.
are not included in the ancillary expenses. 
  

	5.4.2	Invoicing 

 The Landlord will issue an annual invoice for the effective ancillary expenses, the
balance of which must be paid within 30 days of presentation. Based on the annual invoice, the Landlord is entitled to reset the amount of the payments on account, also during the minimum contract period. 

The invoice, respectively the share of ancillary expenses attributable to the Tenant, is calculated in accordance with a formula to be
determined by an expert. 
 The Tenant is entitled to inspect the overall ancillary expense accounts with the receipts during a period of 30
days after presentation of the invoice. The ancillary expense accounts will be deemed accepted if the Tenant does not object in writing during this inspection period. 
  

	5.5	Interest 

 The above agreed payment dates are due dates on which the Tenant enters into default
without further notice if rent payments remain outstanding. In this case, interest of 5% is due. In addition, the Tenant must reimburse the Landlord for default notice and collection expenses. 

 

	5.6	Value added tax 

 At the present date the leased area is not opted in [voluntarily subject to
VAT]. Accordingly the rent is stated net of value added tax. The Landlord reserves the right to opt in the leased area at a future point in time. If the Landlord is considering an opt in, the Tenant undertakes to provide the Landlord promptly and
free of charge with all documents relevant for the opt in. The Tenant will be notified accordingly at the relevant time. 
 If the leased
area is opted in, the above rent and ancillary expenses as well as the shared costs will be deemed exclusive of any value added tax. 

  
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             Initials Tenant              

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 Commercial Lease Agreement 
  

	5.7	Taxes, fees, public charges 

 Taxes, fees, public charges, costs for electricity, gas and
telephone and all other costs that arise exclusively from the operation of the Tenant’s business are to be paid separately by the Tenant. Additional connection fees for water, electricity, waste disposal etc. that are incurred as a result of
Tenant fit out of the lease object are to be paid by the Tenant. 
  

	6.	Fit out and usage of the lease object 

  

	6.1	Condition and use of the lease object 

  

	6.1.1	Condition of the lease object 

 The lease object will be leased to the Tenant in accordance with
the fit out description. This state was reflected accordingly in the calculation of the base rent. The fit out description, which is a fully integrated part of this lease agreement, states the binding cost allocation between the Landlord and the
Tenant regarding the fit out, maintenance and renovation of the lease object. The obligations of the Landlord pursuant to the fit out description have been fulfilled in full. A fit out of the leased premises beyond the scope of the fit out
description is considered as a Tenant fit out. Any fit out made by a previous Tenant that do not qualify as basic work and which is taken over by the Tenant is deemed done by him (= Tenant fit out). All costs for Tenant fit outs, their maintenance
and removal are in all cases to be borne exclusively by the Tenant. 
  

	6.1.2	Modification of the lease object by the owner 

  

	 	•	 	Replacement of flooring in the entire leased premises 

 (cost ceiling CHF 30’000.00.) 

 

	 	•	 	Painting of the entire leased area 

 (cost ceiling CHF 10’000.00) 

 

	 	•	 	Installation of tea kitchen with small fridge and dishwasher 

 (cost ceiling CH 6’000.00)

  

	 	•	 	Installation of a shower 

 (cost ceiling CHF 3’000.00) 

The above mentioned fit out will be executed by the owner. If the Tenant’s wishes regarding the fit out exceed the above-mentioned cost
ceilings, these costs will be borne by the Tenant. (Acceptance of costs by the owner of CHF 49’000.00 including VAT) 
  

	6.1.3	Duty of care and tolerance 

 The Tenant undertakes to use the lease object with due care within
the meaning of art. 257f of the Code of Obligations and in particular to maintain the lease object in a good and clean condition. The Tenant will be liable to pay compensation for damage that is not the result of proper use or force majeure. The
Tenant is obliged to notify the Landlord 

  
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 Commercial Lease Agreement 
  

 
immediately of defects in the lease object for which the Tenant does not have to repair itself. In the absence of notice, the Tenant is liable for the resulting damage. The Tenant is obliged to
comply with the rules issued by the Landlord regarding, amongst others, deliveries, use of the goods elevators, waste disposal etc. The Tenant is obliged to tolerate the passage of pipes, tubes and cables in the ceiling space and in the flooring
without compensation. 
  

	6.1.4	Use 

 Use and purpose of usage of the lease object shall be based exclusively on the terms of
this agreement and cannot be changed without the Landlord’s prior written consent. The rights and requirements of the other tenants must be respected in a reasonable way. 
  

	6.1.5	Emergency exits and shelters 

 Emergency exits are to be kept free from obstructions. Shelters
used for purposes other than civilian protection (storage, archive rooms etc.) must be available for use as civilian protection shelters at all times within 24 hours. No modifications may be made to the existing installations in such shelters. 

 

	6.1.6	Modification of the lease object 

 If the Tenant itself wishes to renovate or modify the lease
object or its own installations inside the lease object at its own cost, it must obtain the prior written consent of the Landlord (art. 260a para 1 of the Code of Obligations). The Landlord may give approval subject to provision of security. The
amount of the security is dependent on the overall cost estimate for the renovation works. 
 Subject to other individual written agreements,
the Landlord gives any consent only under the express condition that the Tenant reinstates the lease object to its previous condition at the Tenant’s own cost on termination of the lease agreement (art. 260a para 2 of the Code of Obligations).
If the Landlord waives the right to require the reinstatement of the previous condition, the Tenant is obliged to leave the renovations unchanged in the lease object and the Tenant waives any claim for compensation therefore, where the renovations
or modifications made by the Tenant have resulted in a value enhancement. 
 If the renovation or modification work involves electric
installations, the Tenant is obliged to provide the Landlord after completion of the renovation work and without being requested to do so with an appropriate safety certificate of a certified electrician. The resulting costs will be borne by the
Tenant. For each construction project, a principal’s liability insurance is mandatory. Where approved interventions take place in the general parts of the building, in particular in the structure, installations and building shell, The Landlord
has the right, to set requirements with regard to the planners and/or companies/products/systems to be used. The building structure must not be negatively affected. 

  
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 Commercial Lease Agreement 
  

 The Tenant takes all required measures to ensure that no construction worker liens are
registered in connection with the Tenant’s renovation and modification work and undertakes to use appropriate means (provision of security) to ensure the immediate deletion of such registrations. This applies already at the stage of the
provisional-preventative registration. A breach of this obligation gives the Landlord, after unsuccessful warning with setting of a deadline to comply, a right of extraordinary termination of the lease agreement and to claim for compensation. 

The Tenant bears all costs resulting from its modifications of the lease object. These costs include in particular the defense or assumption of
claims by third parties such as compensation claims and claims for rent reduction of neighboring tenants as a result of construction noise, any compensation of costs for the removal of half-finished Tenant work of no value etc. 

 

	6.1.7	Building and business permits 

 The Tenant is responsible for obtaining all special permits that
are necessary for the Tenant’s business, and the costs therefore are to be borne by the Tenant. 
  

	6.2	Handover of keys 

 Security cylinders were installed on all exterior doors. Upon handover of the
lease object, the Tenant receives 1 key per lock and 5 keys per security lock. The costs for additional keys have to be borne by the Tenant. Upon return of the lease object, the Tenant shall return all keys. In case of any key loss, the Tenant is
responsible for all costs resulting from amendments to the master key plan of the property. 
  

	6.3	Insurance / surveillance 

  

	6.3.1	Responsibility 

 The Landlord obtains the usual liability and property insurance for the
property at its own cost. 
 The Tenant is responsible for obtaining the insurance necessary for the operation of the Tenant’s business
such as insurance for theft, liability insurance, interruption of business insurance, employee and furnishings insurance and insurance for goods storage etc. and the costs resulting from this insurance are borne by the Tenant. The conclusion of a
liability insurance policy is mandatory for the Tenant. In addition, all other investments and installations carried out and paid for by the Tenant are to be insured by the Tenant. Premium adjustments for progressive building insurance resulting
from the Tenant fit out of the lease object are to be borne proportionately by the Tenant. 
 The Landlord assumes no responsibility for shop
windows, lettering on shop windows, display cabinets, panes of glass, decoration of glass walls, company signs, neon writing etc. The Tenant is responsible for insuring against such damage. The Tenant alone is responsible for the safety (burglary,
theft) and the surveillance of the leased rooms. 

  
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	6.3.2	Delimitation of building and furnishing 

 The then valid provisions of the cantonal Building
Insurance Institute shall apply to determine the delimitation between building and furnishings. In case of uncertainty, the cantonal Building Insurance Institute’s assessment protocol shall prevail. 

 

	6.4	Company signs, advertising, lettering and marketing activities 

  

	6.4.1	Signage and lettering 

 Company and advertising signs, posters, display cabinets etc. may only
be put up with the written consent of the Landlord and only at the points of the building intended therefor. The costs are borne by the Tenant. The Landlord decides on color, size, material, arrangement and order of the signs, whereby the wishes of
the Tenant will be taken into consideration. The Tenant shall preferably use the original logo of its company. In case of renovation or change to the facades or other walls, the Tenant must remove and reinstall the signs and logos at its own cost.

 Applications for the any required governmental permits are to be presented to the Landlord for signing in a form fit for approval. All
costs and fees relating thereto are to be borne by the Tenant. In addition, the Tenant must pay the connection costs and for any electricity usage. 

The Tenant is obliged to participate in the cost of information boards and advertising towers that may be in the interests of general customer
orientation and to bear the relevant share of the costs. 
 The Tenant is obligated to refer to the property as a whole in its own
advertising and to use the official sign of the property. 
  

	6.5	Parking spaces 

 If a parking garage is available to customers of the commercial property
against payment, the costs for its service, surveillance, cleaning and maintenance are borne by the Landlord; the income belongs to the Landlord. 
  

	6.6	Right to inspect 

 The Landlord is entitled to enter the leased premises during business hours,
on giving 24 hours advance notice, in order to preserve its ownership rights and for the necessary viewings for a re-rental. 

  
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	6.7	Sublease 

  

	6.7.1	Permission 

 A sublease of all or part of the lease object requires the written consent of the
Landlord. The Landlord may only withhold consent based on important reasons in accordance with the provisions of art. 262 of the Code of Obligations. Grounds of refusal include among others a change in the range of products or in the duty to pay
VAT. 
 The Tenant undertakes that any sublease agreement will be concluded in writing and to require the sub-tenant to comply with all of
the obligations in this lease agreement, in particular also concerning calculation and notification of turnover. One copy of the sublease agreement must be made available to the Landlord. 

 

	6.7.2	Liability 

 Also in case of a sublease, the Tenant will be fully liable for complying with all
of its obligations under this agreement, in particular with regard to the use of the lease object pursuant to Section 3 and the payment in full of rent, ancillary expenses and contributions to the tenant association for advertising fees. 

 

	6.8	Maintenance by the Tenant 

 The Tenant is required to maintain the leased premises, the
installations and facilities contained therein and the common areas and installations used by the Tenant in an orderly and clean condition. 

Maintenance, servicing, repairs, renovation and replacement of the Tenant’s technical installations and facilities is the Tenant’s
responsibility. 
 For all installations, machines and apparatus made available by the Landlord that are for the sole use of the Tenant, the
Tenant must ensure at its own cost the regular maintenance in accordance with the recommendations of the manufacturer. 
 Any maintenance,
renovation or repair work on the leased objects and facilities made available to the Tenant by the Landlord that is not attributable to ordinary wear and tear (i.e. in line with their use in accordance with the contract) will be at the Tenant’s
cost. 
  

	6.8.1	Instruction of work 

 Maintenance and repair work on the lease object, and in particular on the
corresponding facilities and installations (also those outside the lease object), that is instructed by the Tenant must be conducted by certified experts. 

The Landlord, or the representative mandated by the Landlord, is to be informed of the type, extent and duration of the work prior to the work
being carried out. 

  
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	6.8.2	Minor repairs 

 The costs of all minor repairs within the lease object, where the cost does not
exceed 1 % of the annual net rent or maximum CHF 2’000.00 in each individual case, are to be borne by the Tenant. 
  

	7.	Return of the lease object 

  

	7.1	Return upon termination of the lease agreement 

 The lease object must be returned in a clean
and good state on the day of termination of the lease (art. 267 of the Code of Obligations). The Landlord draws up a protocol that states the condition of the lease object. The protocol must be signed by both parties and constitutes a notice of
defects within the meaning of art. 267a para 1 of the Code of Obligations for the objections recorded therein. The Landlord is entitled to have removed at the Tenant’s cost those defects stated in the protocol for which the Tenant is
responsible. In case of subsequent discovery of defects that were not identifiable during the final inspection of the lease object, the Tenant is also responsible for these to the extent they have been notified by the Landlord immediately. 

 

	7.2	Re-instatement of the previous state / duty to dismantle 

 To the extent the Landlord has agreed
pursuant to Section 6.1.6 to interior fit outs, renovations and modifications or the Tenant has taken over fit outs of the previous tenant and nothing to the contrary has been agreed in writing in the specific case, the Tenant must re-instate,
at the end of the lease, in a professional manner and at the Tenant’s own cost, the original condition of the lease object pursuant to the fit out description. The same applies if such work has been conducted without the Landlord’s written
consent. 
  

	8.	Final provisions 

  

	8.1	Contractual security 

  

	8.1.1	Amount 

 To secure all claims arising from the lease agreement, the Tenant furnishes a cash
security in the form of a rent deposit pursuant to art. 257e of the Code of Obligations or an irrevocable bank guarantee from a large or cantonal Swiss bank made out in favour of the Landlord, not the Representative, for an amount of CHF
38’000.00. The bank guarantee is indefinite or for the duration of the lease plus 12 months and is to be renewed accordingly upon exercise of the option right. 
  

	8.1.2	Time of delivery 

 The contractual security must be in the Landlord’s possession at the
latest on commencement of the lease, i.e. the bank guarantee must be handed over to the Landlord or the deposit must be paid into the deposit account. If this is not done on time, the Landlord 

  
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may refuse the handover of the lease object to the Tenant until the bank guarantee or deposit has been provided. This right is also available to the Landlord if a handover of the lease object is
agreed prior to the commencement of the lease and the security to be provided is not in the Landlord’s possession at this point in time. As the delayed handover of the lease object is caused by the Tenant, the rent (net rent, ancillary expenses
and any other agreed costs) is nevertheless due from the date of start of the lease; also the Tenant has no resultant claim for any compensation whatsoever. 
  

	8.2	Integrated elements of this agreement 

 The following attached documents constitute integral
parts of this agreement: 
 Annex 1: floor plan 

Annex 2: fit out description 
  

	8.3	Contract amendments 

 Amendments and supplements to this agreement and its integrated parts
require the written form. This also applies to the waiver of the requirement of written form. 
  

	8.4	Duty of disclosure 

 The Tenant is obliged to inform the Landlord without delay with respect to
all changes of a legal and business nature that have a substantial impact on the company’s structure. All documents required by the Landlord are to be made available to the Landlord free of charge. 

 

	8.5	Severability 

 The invalidity or unenforceability of individual provisions of this agreement
does not affect the legal validity of the agreement as a whole. The ineffective provision shall be replaced by a provision that comes closest legally and commercially to the original, unenforceable provision. 

 

	8.6	Subsidiary law and place of jurisdiction 

 Swiss law is exclusively applicable. If this
agreement does not contain any provisions, or does not contain any provisions to the contrary, the provisions of art. 253 et seq. of the Code of Obligations on lease shall apply. 

For any disputes arising out of this lease agreement, the parties submit to the competent authorities at the place where the object is located.

  
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	8.7	Copies of the agreement 

 This lease agreement is executed in duplicate and the parties each
receive one executed copy. 
  

					
	Oberwil, 15 January 2013	 		  	
			
	For the Landlord: the Representative	 		  	The Tenant
	PRIVERA AG	 		  	Auris Medical AG
			
	 [Signature]
	 		  	 [Signature]

		 		  	Thomas Meyer, Managing Director

  
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