Document:

exv10w02

 

Exhibit 10.02

2001 STOCK OPTION PLAN

Amended and Restated December 19, 2005

Section 1. General Purpose of Plan; Definitions.

     The name of this plan is the 2001 Stock Option Plan (the “Plan”). The Plan was adopted by the
Board (defined below) on April 23, 2001, subject to the approval of the shareholders of Genelabs
Technologies, Inc. (the “Company”). The purpose of the Plan is to enable the Company to attract,
retain and provide equity incentives to selected persons to promote the financial success of the
Company.

     For purposes of the Plan, the following terms shall be defined as set forth below:

     (1) “Administrator” means the Board, or if and to the extent the Board does not
administer the Plan, the Committee in accordance with Section 2 below.

      (2) “Affiliate” means any corporation that directly, or indirectly through one or more
intermediaries, controls or is controlled by, or is under common control with, another
corporation, where “control” (including the terms “controlled by” and “under common control
with”) means the possession, direct or indirect, of the power to cause the direction of the
management and policies of the corporation, whether through the ownership of voting
securities, by contract or otherwise.

      (3) “Board” means the Board of Directors of the Company.

      (4) “Change in Control” means a change in the ownership or control of the Company,
effected through any of the following events:

      (a) any “person,” as such term is used in Sections 13(d) and 14(d) of the
Exchange Act (other than the Company; any trustee or other fiduciary holding
securities under an employee benefit plan of the Company; or any company owned,
directly or indirectly, by the shareholders of the Company in substantially the same
proportions as their ownership of Common Stock of the Company) is or becomes, after
the Effective Date (as defined herein), the “beneficial owner” (as defined in Rule
13d-3 under the Exchange Act), directly or indirectly, of securities of the Company
(not including in the securities beneficially owned by such person any securities
acquired directly from the Company or its affiliates) representing twenty-five
percent (25%) or more of the combined voting power of the Company’s then outstanding
securities;

      (b) during any period of two consecutive years (not including any period prior
to the Effective Date), individuals who at the beginning of such period constitute
the Board, and any new director (other than a director designated by a person who has
entered into an agreement with the Company to effect a transaction described in
clause (a), (c) or (d) of this definition) whose election by the Board or nomination
for election by the Company’s shareholders was approved by a vote of at least two thirds (
2¤3) of the directors then still in office who either were
directors at the beginning of the period or whose election or

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nomination for election
was previously so approved, cease for any reason to constitute at least a majority
thereof;

      (c) the shareholders of the Company approve a merger or consolidation of the
Company with any other corporation, other than (A) a merger or consolidation which
would result in the voting securities of the Company outstanding immediately prior
thereto continuing to represent (either by remaining outstanding or by being
converted into voting securities of the

surviving entity), in combination with the ownership of any trustee or other
fiduciary holding securities under an employee benefit plan of the Company, at least
sixty percent (60%) of the combined voting power of the voting securities of the
Company or such surviving entity outstanding immediately after such merger or
consolidation or (B) a merger or consolidation effected to implement a
recapitalization of the Company (or similar transaction) in which no person acquires
more than fifty percent (50%) of the combined voting power of the Company’s then
outstanding securities; or

      (d) the shareholders of the Company approve a plan of complete liquidation of
the Company or an agreement for the sale or disposition by the Company of all or
substantially all of the Company’s assets.

      (5) “Code” means the Internal Revenue Code of 1986, as amended from time to time, or
any successor thereto.

      (6) “Committee” means the Compensation Committee of the Board plus such additional
individuals as the Board shall designate in order to meet the qualifications referred to in
Section 162(m) of the Code and Rule 16b-3 as promulgated by the Securities and Exchange
Commission under the Exchange Act or any other committee the Board may subsequently appoint
to administer the Plan. Unless otherwise determined by the Board, the Committee shall be
composed entirely of members who meet the qualifications referred to in Rule 16b-3 under the
Exchange Act (“Rule 16b-3”) and Section 162(m) of the Code. If at any time the Board shall
not administer the Plan, then the functions of the Board specified in the Plan shall be
exercised by the Committee.

      (7) “Common Stock” means the common stock, no par value per share, of the Company.

      (8) “Company” means Genelabs Technologies, Inc., a corporation organized under the laws
of the State of California (or any successor corporation).

      (9) “Disability” has the meaning as set forth in Section 22(e)(3) of the Code.

      (10) “Disinterested Person” shall have the meaning set forth in Rule 16b-3, and as such
Rule may be amended from time to time, or any successor definition adopted by the SEC.

      (11) “Effective Date” shall mean the date provided pursuant to Section 11.

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      (12) “Eligible Recipient” means an employee, officer, director, consultant, independent
contractor or advisor (provided such consultant, independent contractor or advisor renders
bona fide services not in connection with the offer or sale of securities in a
capital-raising transaction) of the Company or any Parent, Subsidiary or Affiliate of the
Company eligible to participate in the Plan pursuant to Section 4.

      (13) “Exchange Act” means the Securities Exchange Act of 1934, as amended from time to
time, or any successor thereto.

      (14) “Fair Market Value” means, as of any given date, the fair market value of a Share
as determined by the Committee from time to time in good faith; provided that (i) if the
Shares are admitted to trading on a national securities exchange, the fair market value of a
Share on any date shall be the closing price per Share reported on the last date preceding
such date on which a sale was reported, (ii) if the Shares are admitted to quotation on the
National Association of Securities Dealers Automated Quotation (“Nasdaq”) System or other
comparable quotation system and has been designated as a National Market System (“NMS”)
security, the fair market value of a Share on any date shall be the closing price per Share
reported on the last trading day preceding such date as quoted on the Nasdaq and as reported
in the Wall Street Journal.

      (15) “Incentive Stock Option” means any Stock Option intended to be designated as an
“incentive stock option” within the meaning of Section 422 of the Code.

      (16) “Non-Qualified Stock Option” means any Stock Option that is not an Incentive Stock
Option, including any Stock Option that provides (as of the time such Stock Option is
granted) that it will not be treated as an Incentive Stock Option.

      (17) “Optionee” means any Eligible Recipient selected by the Administrator, pursuant to
the Administrator’s authority in Section 2 below, to receive grants of Stock Options.

      (18) “Parent” means any corporation (other than the Company) in an unbroken chain of
corporations ending with the Company, if each of the corporations in the chain (other than
the Company) owns stock possessing 50% or more of the combined voting power of all classes
of stock in one of the other corporations in the chain.

     (19) “SEC” means the Securities and Exchange Commission.

      (20) “Securities Act” means the Securities Act of 1933, as amended, from time to time,
or any successor thereto.

      (21) “Share” means a share of the Common Stock.

      (22) “Stock Option” means an option to purchase Shares granted pursuant to Sections 5
and 6 below.

      (23) “Subsidiary” means any corporation (other than the Company) in an unbroken chain
of corporations beginning with the Company, if each of the corporations (other than the last

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corporation in the unbroken chain) owns stock possessing 50% or more of the total combined
voting power of all classes of stock in one of the other corporations in the chain.

      (24) “Ten Percent Shareholder” means a person who owns or is deemed to own (by reason
of the attribution rules applicable under Section 424(d) of the Code) more than 10% of the
combined voting power of all classes of stock of the Company or of any Parent or Subsidiary.

Section 2. Administration.

     The Plan shall be administered in accordance with the requirements of Section 162(m) of the
Code (but only to the extent necessary and desirable to maintain qualification of awards under the
Plan under Section 162(m) of the Code) and, to the extent applicable, Rule 16b-3, by the Board or,
at the Board’s sole discretion, by the Committee, which shall be appointed by the Board, and which
shall serve at the pleasure of the Board.

     Pursuant to the terms of the Plan, the Administrator shall have the power and authority to
grant Stock Options to Eligible Recipients pursuant to the terms of the Plan. The Administrator may
delegate to officers of the Company the authority to grant Stock Options under this Plan to
Eligible Recipients who are not officers or directors of the Company whose transactions in the
Company’s Common Stock are subject to Section 16(b) of the Exchange Act.

     Additionally, subject to the terms and provisions of the Plan, the Administrator’s powers
shall include, without limitation, the authority to:

     (1) select those Eligible Recipients who shall be Optionees;

     (2) determine whether and to what extent Stock Options are to be granted hereunder to
Optionees including whether a Stock Option is to be an Incentive Stock Option or a
Non-Qualified Stock Option;

     (3) determine the number of Shares to be covered by each such Stock Option granted
hereunder, the exercise price of a Stock Option and the period during which the Stock Option
may be exercised;

     (4) determine other terms and conditions, not inconsistent with the terms of the Plan,
of each Stock Option granted hereunder;

     (5) determine whether an Optionee has ceased to be employed or retained by the Company
or any Parent, Subsidiary or Affiliate of the Company and the effective date on which such
employment terminated and whether an Optionee who is a director, consultant, independent
contractor or advisor is employed or retained by the Company or any Parent, Subsidiary or
Affiliate of the Company;

     (6) adopt, alter and repeal such administrative rules, guidelines and practices
governing the Plan as it shall from time to time deem advisable;

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     (7) interpret the terms and provisions of the Plan and any award issued under the Plan
(and any agreements relating thereto); and

     (8) otherwise supervise the administration of the Plan.

     All decisions and interpretations made by the Administrator pursuant to the provisions of the
Plan shall be final, conclusive and binding on the Company and all persons having an interest in
any Stock Option or any Shares purchased pursuant to a Stock Option.

Section 3. Stock Subject to Plan.

     The total number of Shares reserved and available for issuance under the Plan shall be
1,700,000 (after giving effect to the one-for-five stock split). Such Shares may consist, in whole
or in part, of authorized and unissued shares or treasury shares. No one Optionee shall be eligible
to receive more than 100,000 Shares (after giving effect to the one-for-five stock split) during
any single calendar year during the term of this Plan pursuant to the grant of Stock Options
hereunder. Upon shareholder approval of the Plan, (1) the Company’s 1995 Stock Option Plan (the
“1995 Plan”) shall be merged and incorporated into the Plan, effective immediately prior to the
2001 annual meeting of the shareholders of the Company, (2) all outstanding options under the 1995
Plan shall be treated as outstanding under the Plan; provided however, that each outstanding option
so incorporated shall be governed solely by the express terms and conditions of the 1995 Plan and
all other instruments evidencing the grant of such options, and (3) all available shares for grant
under the 1995 Plan as of such date shall be available for grant hereunder, and any and all shares
that would otherwise be returned to the 1995 Plan by reason of expiration of its term or
cancellation upon termination of employment or service shall be available again for grant hereunder
as of such date of cancellation or termination. Effective immediately prior to the 2001 annual
meeting of the shareholders of the Company, and subject to shareholder approval of the Plan at such
meeting, the 1995 Plan shall terminate and no further option grants shall be made therefrom.

     Consistent with the provisions of Section 162(m) of the Code, as from time to time applicable,
to the extent that a Stock Option expires or is otherwise terminated without being exercised, such
Shares shall again be available for issuance in connection with future awards granted under the
Plan. If any Shares have been pledged as collateral for indebtedness incurred by an Optionee in
connection with the exercise of a Stock Option and such Shares are returned to the Company in
satisfaction of such indebtedness, such Shares shall again be available for issuance in connection
with future awards granted under the Plan.

     In the event of any merger, reorganization, consolidation, recapitalization, stock dividend,
stock split, combination or other change in the capital structure of the Company, as may be
determined by the Administrator, in its sole discretion and subject to any required action by the
Board or shareholders of the Company and compliance with applicable securities laws, a substitution
or adjustment shall be made in (i) the aggregate number of Shares reserved for issuance under the
Plan and (ii) the kind, number and option price of Shares subject to outstanding Stock Options
granted under the Plan; provided, however, that the number of shares subject to any award shall
always be a whole number; and provided further, that the exercise price may not be decreased to
below the par value, if any, for the Shares. Such other substitutions or adjustments shall be made as may be determined by the Administrator, in its sole
discretion. In connection with any event described in this paragraph, the Administrator may
provide, in its sole discretion, for the cancellation of any outstanding awards and payment in cash
or other property therefor.

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Section 4. Eligibility.

     Non-Qualified Stock Options may be granted to employees, directors, consultants, officers,
independent contractors and advisors (provided such consultants, independent contractors and
advisors render bona fide services not in connection with the offer or sale of securities in a
capital-raising transaction) of the Company or any Parent, Subsidiary or Affiliate of the Company.
Incentive Stock Options may be granted only to employees (including officers and directors who are
also employees) of the Company or a Parent or Subsidiary of the Company.

Section 5. Stock Options.

     The Stock Options granted under the Plan may be of two types: (i) Incentive Stock Options and
(ii) Non-Qualified Stock Options. The Administrator shall have the authority to grant to any
Eligible Recipient Incentive Stock Options, Non-Qualified Stock Options, or both types of Stock
Options. To the extent that any Stock Option does not qualify as an Incentive Stock Option, it
shall constitute a separate Non-Qualified Stock Option. More than one Stock Option may be granted
to the same Optionee and be outstanding concurrently hereunder.

     Any Stock Option granted under the Plan shall be in such form as the Administrator may from
time to time approve, and the provisions of Stock Option awards need not be the same with respect
to each Optionee. Stock Options granted under the Plan shall be subject to the following terms and
conditions and shall contain such additional terms and conditions, not inconsistent with the terms
of the Plan, as the Administrator shall deem desirable:

      (1) Form of Stock Option Grant. Optionees who are granted Stock Options shall enter
into a stock option agreement with the Company, in such form (which need not be the same for
each Optionee) as the Administrator shall from time to time approve, which stock option
agreement shall comply with and be subject to the terms and conditions of this Plan.

      (2) Date of Grant. The date of grant of a Stock Option shall be the date on which the
Administrator makes the determination to grant such Stock Option unless otherwise specified
by the Administrator. The stock option agreement representing the Stock Option will be
delivered to the Optionee with a copy of this Plan within a reasonable time after the
granting of the Stock Option.

      (3) Exercise Price. The option price per Share purchasable under a Stock Option shall
be determined by the Administrator, in its sole discretion, on the date the Stock Option is
granted; provided that (i) the exercise price of a Non-Qualified Stock Option shall not be
less than 100% of the Fair Market Value of the Shares on the date the Stock Option is
granted; (ii) the exercise price of an Incentive Stock Option shall be not less than 100% of
the Fair Market Value of the Shares on the date the Stock Option is granted; and (iii) if an
Incentive Stock Option is granted to a Ten Percent Shareholder, the exercise price of such Incentive Stock Option, to the extent
required at the time of grant by the Code, shall be no less than 110% of the Fair Market
Value of the Common Stock on the date such Incentive Stock Option is granted.

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      (4) Exercise Period. Subject to this Section 5 and Section 10 herein, Stock Options
shall be exercisable within the times or upon the events determined by the Administrator as
set forth in the respective stock option agreement; provided, however, that no Stock Option
shall be exercisable after the expiration of ten (10) years from the date the Stock Option
is granted and provided, further, that no Incentive Stock Option granted to a Ten Percent
Shareholder shall be exercisable after the expiration of five (5) years from the date the
Stock Option is granted; provided further, that so long as the Stock Options and Common
Stock issued under the Plan must be qualified under Section 25111 of the California
Corporate Securities Law of 1968, as amended, Stock Options granted subsequent to October
13, 2005 shall include the right to exercise the Stock Options at the rate of at least 20%
per year over the five years following the grant date of such Stock Options.

      (5) Limitations on Incentive Stock Options. The aggregate Fair Market Value
(determined as of the time the Incentive Stock Option is granted) of Shares with respect to
which Incentive Stock Options are exercisable for the first time by an Optionee during any
calendar year (under this Plan or under any other incentive stock option plan of the Company
or of any Parent or Subsidiary) shall not exceed $100,000. If the Fair Market Value of
Shares with respect to which Incentive Stock Options are exercisable for the first time by
an Optionee during any calendar year exceeds $100,000, the Stock Options for the first
$100,000 worth of Shares to become exercisable in such year shall be Incentive Stock Options
and the Stock Options for the amount in excess of $100,000 that become exercisable in that
year shall be Non-Qualified Stock Options. In the event that the Code or the regulations
promulgated thereunder are amended after the effective date of this Plan to provide for a
different limit on the Fair Market Value of Shares permitted to be subject to Incentive
Stock Options, such different limit shall be incorporated herein and shall apply to any
Stock Options granted after the effective date of such amendment.

      (6) Stock Options Non-Transferable. Stock Options granted under this Plan, and any
interest therein, shall not be transferable or assignable by an Optionee, and may not be
made subject to execution, attachment or similar process, otherwise than by will or by the
laws of descent and distribution, and shall be exercisable during the lifetime of the
Optionee only by such Optionee; provided, however, that Non-Qualified Stock Options may be
transferred to such family members, trusts and charitable institutions as the Administrator,
in its sole discretion, shall approve at the time of the grant of such Stock Option.

      (7) Assumed Stock Options. In the event the Company assumes a stock option granted by
another company unless otherwise determined by the Administrator, the terms and conditions
of such option shall remain unchanged (except the exercise price and the number and nature
of shares issuable upon exercise, which will be adjusted appropriately pursuant to Section
424(a) of the Code). In the event the Company elects to grant a new stock option rather than
assuming an existing option, such new option may be granted with a similarly adjusted
exercise price.

     (8) Exercise of Stock Options.

      (a) Notice. Stock Options may be exercised only by delivery (including
electronic delivery or other delivery method approved by the Administrator) to the
Company of a written stock option exercise agreement in a form approved by the
Administrator (which need not be the same for each Optionee), stating the number of
Shares being purchased, the

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restrictions imposed on the Shares, if any, and such
representations and agreements regarding the Optionee’s investment intent and access
to information, if any, as may be required by the Company to comply with applicable
securities laws, together with payment in full of the exercise price for the number
of Shares being purchased.

      (b) Payment. Payment for the Shares may be made in cash (by check) or, where
approved by the Administrator in its sole discretion at the time of grant and where
permitted by law: (i) by cancellation of indebtedness of the Company to the Optionee;
(ii) by surrender of Shares having a Fair Market Value equal to the applicable
exercise price of the Stock Options that have been owned by the Optionee for more
than six (6) months (and which have been paid for within the meaning of SEC Rule 144
and, if such Shares were purchased from the Company by use of a promissory note, such
note has been fully paid with respect to such shares), or were obtained by the
Optionee in the open public market; (iii) by waiver of compensation due or accrued to
the Optionee for services rendered; (iv) provided that a public market for the
Company’s stock exists, through a “same day sale” commitment from the Optionee and a
broker-dealer that is a member of the National Association of Securities Dealers (an
“NASD Dealer”) whereby the Optionee irrevocably elects to exercise the Stock Option
and to sell a portion of the Shares so purchased to pay for the exercise price and
whereby the NASD Dealer irrevocably commits upon receipt of such Shares to forward
the exercise price directly to the Company; (v) provided that a public market for the
Company’s stock exists, through a “margin” commitment from the Optionee and an NASD
Dealer whereby the Optionee irrevocably elects to exercise the Stock Option and to
pledge the Shares so purchased to the NASD Dealer in a margin account as security for
a loan from the NASD Dealer in the amount of the exercise price, and whereby the NASD
Dealer irrevocably commits upon receipt of such Shares to forward the exercise price
directly to the Company; (vi) by any combination of the foregoing; or (vii) by any
other method approved by the Administrator.

      (c) Withholding Taxes. Prior to issuance of the Shares upon exercise of a
Stock Option, the Optionee shall pay to the Company, or make arrangements
satisfactory to the Administrator regarding payment of, any Federal, state, or local
taxes of any kind required by law to be withheld with respect to such Stock Option.
The obligations of the Company under the Plan shall be conditional on the making of
such payments or arrangements, and the Company shall, to the extent permitted by law,
have the right to deduct any such taxes from any payment of any kind otherwise due to
the Optionee.

      (d) Limitations on Exercise. The exercisability of a Stock Option shall be
subject to the following:

      (i) The Administrator may specify a reasonable minimum number of Shares
that may be purchased on any exercise of a Stock Option, provided that such
minimum number will not prevent an Optionee from exercising the full number of
Shares as to which the Stock Option is then exercisable.

      (ii) A Stock Option shall not be exercisable unless such exercise is in
compliance with the Securities Act, all applicable state securities laws and
the

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requirements of any stock exchange or national market system upon which
the Shares may then be listed, as they are in effect on the date of exercise.
The Company shall be under no obligation to register the Shares with the SEC
or to effect compliance with the registration, qualification or listing
requirements of any state securities laws, stock exchange or national market
system, and the Company shall have no liability for any inability or failure
to do so.

      (9) Termination of Employment or Service Other Than Due to Death or Disability.
Unless otherwise provided in the applicable stock option agreement, if an Optionee ceases to
be employed or retained by the Company or any Parent, Subsidiary or Affiliate of the Company
for any reason except death or Disability, the Optionee may exercise such Optionee’s
Incentive Stock Options or Non-Qualified Stock Options, to the extent that they are
exercisable on the date of termination, within three (3) months after the date of
termination or such other time period as may be specified in the applicable stock option
agreement (but in no event later than the expiration date of the term of such Stock Option
as set forth in Section 5(4) above). To the extent an Optionee was not entitled to exercise
a Stock Option at the date of termination, or if an Optionee does not exercise such Stock
Option to the extent so entitled within the time specified herein, the Stock Option shall
terminate unless as otherwise provided in the applicable stock option agreement.

      (10) Termination of Employment or Service Due to Death or Disability. Unless
otherwise provided in the applicable stock option agreement, if an Optionee’s employment or
retention with the Company or any Parent, Subsidiary or Affiliate of the Company is
terminated because of the Optionee’s death or Disability, the Optionee may exercise such
Optionee’s Incentive Stock Options or Non-Qualified Stock Options, to the extent that they
are exercisable on the date of termination, by the Optionee (or the Optionee’s legal
representative) within twelve (12) months after the date of termination or such other time
period as may be specified in the applicable stock option agreement (but in no event later
than the expiration date of the term of such Stock Option as set forth in Section 5(4)
above). To the extent an Optionee was not entitled to exercise a Stock Option at the date of
termination, or if an Optionee does not exercise such Stock Option to the extent so entitled
within the time specified herein, the Stock Option shall terminate unless as otherwise
provided in the applicable stock option agreement.

Section 6. Option Grants for Non-Employee Directors

     (1) Eligibility Generally. Non-employee directors of the Company or any Parent, Subsidiary
or Affiliate of the Company shall be granted automatic Stock Options pursuant and subject to
Sections 6(2) and (3) below. In addition to the foregoing, Stock Options may be granted to such
non-employee directors of the Company or any Parent, Subsidiary or Affiliate of the Company as the
Administrator shall select from time to time in its sole discretion, and subject to such terms and
conditions as the Administrator shall determine, in its sole discretion. Directors may be granted
more than one Stock Option under the Plan.

     (2) Eligibility for Automatic Stock Options. Each non-employee director, upon his or her
first election or appointment to the Board, will be granted a Stock Option to purchase 6,000 Shares
(after giving effect to the one-for-five stock split). At the
Company’s Annual Meeting of
Shareholders following the second anniversary of his or her election or appointment to the Board,
and at each subsequent Annual

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Meeting of Shareholders, each such director will be granted an
additional Stock Option to purchase 3,000 Shares (after giving effect to the one-for-five stock
split).

     (3) Terms and Conditions of Automatic Stock Options. The terms and conditions of the
automatic Stock Option grants to non-employee directors of the Company or any Parent, Subsidiary or
Affiliate of the Company pursuant to Section 6(2) and this Section 6(3) are as follows:

      (a) Date of Grant. The dates of grant of the automatic Stock Options shall be the
dates described in Section 6 (2) above. The stock option agreement representing the Stock
Option will be delivered to the Optionee within a reasonable time after the granting of the
Stock Option.

      (b) Exercise Price. The exercise price of the automatic Stock Option shall be the
Fair Market Value of the Shares at the time that the Stock Option is granted.

      (c) Vesting and Exercise Period. The automatic Stock Options shall be fully vested
and exercisable in their entirety immediately upon grant for the term set forth in the
applicable stock option agreement; provided, however, that no Stock Option shall be
exercisable after the expiration of ten (10) years from the date the Stock Option is
granted.

      (d) Limitation on Exercise. If the Optionee ceases to be a director for any reason
except death, the Optionee may exercise his or her Stock Options, to the extent (and only to
the extent) that they are exercisable on the date of termination until the expiration dates
of the Stock Options, which shall be ten (10) years from the dates the Stock Options are
granted. If the Optionee ceases to be a director because of death, the Optionee’s legal
representative may exercise his or her Stock Options to the extent (and only to the extent)
that they are exercisable on the date of termination, within twelve (12) months after the
date of termination, but not after the expiration of ten (10) years from the date the Stock
Options are granted. To the extent an Optionee or an Optionee’s legal representative was not
entitled to exercise a Stock Option at the date of termination, or if an Optionee or an
Optionee’s legal representative does not exercise such Stock Option to the extent so
entitled within the time specified herein, the Stock Option shall terminate unless as
otherwise provided in the applicable stock option agreement.

Section 7. Modification, Extension and Renewal of Stock Options

     The Administrator shall have the power to modify, extend or renew outstanding Stock Options
and to authorize the grant of new Stock Options in substitution therefor, provided that any such
action may not, without the written consent of an Optionee, impair any rights under any Stock
Option previously granted except as provided in Section 3 hereof. Any outstanding Incentive Stock
Option that is modified, extended, renewed or otherwise altered shall be treated in accordance with
Section 424(h) of the Code. The Administrator shall not have the power to reduce the exercise price
of outstanding Stock Options.

Section 8. Privileges of Stock Ownership

     No Optionee shall have any of the rights of a shareholder with respect to any Shares subject
to a Stock Option until such Stock Option is properly exercised. No adjustment shall be made for
dividends or distributions or other rights for which the record date is prior to such date, except
as provided in this Plan.

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Upon written request, the Company shall provide to each Optionee a copy
of the annual financial statements of the Company at such time after the close of each fiscal year
of the Company as such statements are released by the Company to its common shareholders generally.

Section 9. No Obligation to Employ

     Nothing in this Plan nor any Stock Option granted under this Plan shall confer on any Optionee
any right to continue in the employ of, as a director of, or other relationship with, the Company
or any Parent, Subsidiary or Affiliate of the Company or limit in any way the right of the Company
or any Parent, Subsidiary or Affiliate of the Company to terminate Optionee’s employment or other
relationship at any time, with or without cause.

Section 10. Change in Control; Assumption of Stock Options by Successors

     In the event of a Change in Control, any or all outstanding Stock Options shall, unless
otherwise provided in an applicable stock option agreement or other agreement, accelerate and
become exercisable in full upon the occurrence of the Change in Control and shall expire
immediately following the occurrence of the Change in Control. To the extent required by applicable
law, the aggregate Fair Market Value of Incentive Stock Options which first become exercisable in
the year of such Change in Control cannot exceed $100,000, and any remaining accelerated options
shall be treated as Non-Qualified Stock Options.

Section 11. Adoption and Shareholder Approval

     This Plan shall become effective on April 23, 2001, the date the Plan was adopted by the Board
(the “Effective Date”). This Plan shall be approved by the shareholders of the Company, in any
manner permitted by applicable corporate law, within twelve months before or after the date this
Plan was adopted by the Board. Upon the Effective Date, the Board may grant Stock Options pursuant
to this Plan; provided that, in the event that shareholder approval is not obtained within the time
period provided herein, all Stock Options granted hereunder shall terminate. No Stock Option that
is issued as a result of any increase in the number of shares authorized to be issued under this
Plan shall be exercised prior to the time such increase has been approved by the shareholders of
the Company and all such Stock Options granted pursuant to such increase shall similarly terminate
if such shareholder approval is not obtained.

Section 12. Term of Plan

     Stock Options may be granted pursuant to this Plan from time to time within a period of ten
(10) years from the Effective Date.

Section 13. Amendment or Termination of Plan

     Subject to Section 7 above, the Administrator may at any time terminate or amend this Plan in
any respect, including but not limited to, amendment of any form of grant, exercise agreement or
instrument to be executed pursuant to this Plan; provided, however, that the Administrator shall
not, without the approval of the shareholders of the Company, amend this Plan in any manner that
requires such shareholder approval pursuant to the Code or the regulations promulgated thereunder
or pursuant to the Exchange Act or

11

 

Rule 16b-3 (or its successor) promulgated thereunder, to the
extent the Administrator intends the Plan to comply with such foregoing requirement or law.

12

 

Section 14. Unfunded Status of Plan.

     The Plan is intended to constitute an “unfunded” plan for incentive compensation. With respect
to any payments not yet made to an Optionee by the Company, nothing contained herein shall give any
Optionee or persons any rights that are greater than those of a general creditor of the Company.

13exv10w04

 

Exhibit 10.04

GENELABS TECHNOLOGIES, INC.

2001 EMPLOYEE STOCK PURCHASE PLAN

Adopted by the Board of Directors on April 23, 2001

As amended December 19, 2005

1. ESTABLISHMENT OF PLAN

     The purpose of the Genelabs Technologies, Inc. 2001 Employee Stock Purchase Plan (the “Plan”)
is to grant options for purchase of common stock, no par value (the “Common Stock”) of Genelabs
Technologies, Inc. (the “Company”) to eligible employees of the Company and its Subsidiaries (as
hereinafter defined). For purposes of this Plan, “Parent Corporation” and “Subsidiary”
(collectively, “Subsidiaries”) shall have the same meanings as “parent corporation” and “subsidiary
corporation” in Sections 424(e) and 424(f), respectively, of the Internal Revenue Code of 1986, as
amended (the “Code”). The Company intends the Plan to qualify as an “employee stock purchase plan”
under Section 423 of the Code (including any amendments to or replacements of such Section), and
the Plan shall be so construed. Any term not expressly defined in the Plan but defined for purposes
of Section 423 of the Code shall have the same definition herein. A total of 800,000 shares (after
giving effect to the one-for-five stock split) of the Company’s Common Stock are reserved for
issuance under the Plan subject to certain adjustments as provided under Section 14 of the Plan.

2. PURPOSE

     The purpose of the Plan is to provide employees of the Company and Subsidiaries designated by
the Board of Directors of the Company (the “Board”) as eligible to participate in the Plan with a
convenient means of acquiring an equity interest in the Company through payroll deductions, to
enhance such employees’ sense of participation in the affairs of the Company and Subsidiaries, and
to provide an incentive for continued employment.

3. ADMINISTRATION

     This Plan shall be administered by the Administrator. For purposes of this plan, the
"Administrator” shall mean the Board, or if and to the extent the Board does not administer the
Plan, a committee appointed by the Board (the “Committee”). If the Committee is not comprised of
“disinterested persons” (“Disinterested Persons”) as defined in Rule 16b-3(d) promulgated under the
Securities Exchange Act of 1934, as amended (the “Exchange Act”), at the time the Company is
registered under the Exchange Act, unless otherwise determined by the Administrator, the
Administrator shall appoint a Committee consisting of not less than three (3) persons (who need not
be members of the Board), each of whom is a Disinterested Person. After registration of the Company
under the Exchange Act, unless otherwise determined by the Administrator or the Board, Committee
members who are not Disinterested Persons may not vote on any matters affecting the administration
of this Plan, but any such member may be counted for determining the existence of a quorum at any
meeting of the Committee. Subject to the provisions of the Plan and the limitations of Section 423
of the Code or any successor provision in the Code, all questions of interpretation or application
of the Plan shall be determined by the Administrator and its decisions shall be final and binding
upon all participants. Members of the Board shall receive no compensation for their services in
connection with the administration of the Plan, other than standard fees as established from time
to time by the Board for services rendered by Board members serving on Board committees. All
expenses incurred in connection with the administration of the Plan shall be paid by the Company.

4. ELIGIBILITY

     Any employee of the Company or the Subsidiaries is eligible to participate in the Plan except
the following:

      (a) employees who are not employed by the Company or Subsidiaries on the day before the
Offering Date (as hereinafter defined);

      (b) employees who are customarily employed for less than twenty (20) hours per week;

1

 

      (c) employees who are customarily employed for less than five (5) months in a calendar year;
or

      (d) employees who, together with any other person whose stock would be attributed to
such employee pursuant to Section 424(d) of the Code, own stock or hold options to purchase
stock or who, as a result of being granted an option under the Plan with respect to such
Offering Period, would own stock or hold options to purchase stock possessing five percent
(5%) or more of the total combined voting power or value of all classes of stock of the
Company or any of its Subsidiaries.

5. OFFERING DATES

     The offering periods of the Plan (each, an “Offering Period”) shall be of twenty-four (24)
months duration commencing on January 1 and July 1 of each year and ending on June 30 and December
31 of each year. Each Offering Period shall consist of four (4) six-month purchase periods
(individually, a “Purchase Period”) during which payroll deductions of the participants are
accumulated under the Plan. The first business day of each Offering Period is referred to as the
"Offering Date.” The last business day of each Purchase Period is referred to as the “Purchase
Date.” Notwithstanding the foregoing, if the fair market value of the Company’s Common Stock on any
Purchase Date is equal to or is less than such fair market value on an Offering Date, then the
Offering Period(s) for such Offering Date(s) shall immediately terminate and a new Offering Period
shall commence for those employees participating in such terminated Offering Period(s) (See also
Section 11(c) hereof). The Administrator shall have the power to change the duration of Offering
Periods or Purchase Periods with respect to offerings without shareholder approval if such change
is announced at least fifteen (15) days prior to the scheduled beginning of the first Offering
Period or Purchase Period to be affected.

6. PARTICIPATION IN THE PLAN

     Eligible employees may become participants in an Offering Period under the Plan upon the
commencement of the next Purchase Period after satisfying the eligibility requirements by
delivering a subscription agreement to the Company’s or Subsidiary’s (whichever employs such
employee) Treasury Department (the “Treasury Department”) not later than the business day before
such Offering Period begins unless an earlier time for filing the subscription agreement
authorizing payroll deductions is set by the Administrator for all eligible employees with respect
to a given Offering Period. An eligible employee who does not deliver a subscription agreement to
the Treasury Department by such date after becoming eligible to participate in such Offering Period
shall not participate in that Offering Period or any subsequent Offering Period unless such
employee enrolls in the Plan by filing a subscription agreement with the Treasury Department not
later than the business day preceding the beginning of a subsequent Offering Period. Once an
employee becomes a participant in an Offering Period, such employee will automatically participate
in the next Offering Period unless the employee withdraws from the Plan or terminates further
participation in a Purchase Period as set forth in Section 11 hereof. Such participant is not
required to file any additional subscription agreement in order to continue participation in the
Plan.

7. GRANT OF OPTION ON ENROLLMENT

     Enrollment by an eligible employee in the Plan with respect to an Offering Period will
constitute the grant (as of the Offering Date) by the Company to such employee of an option to
purchase on the Purchase Date up to that number of shares of Common Stock of the Company determined
by dividing the amount accumulated in such employee’s payroll deduction account during such
Purchase Period by the lesser of (i) eighty-five percent (85%) of the fair market value of a share
of the Company’s Common Stock on the Offering Date or (ii) eighty-five percent (85%) of the fair
market value of a share of the Company’s Common Stock on the Purchase Date; provided, however, that
the number of shares of the Company’s Common Stock subject to any option granted pursuant to this
Plan shall not exceed the limitations provided under Sections 10(a) and 10(b) below. Fair market
value of a share of the Company’s Common Stock shall be determined as provided in Section 8 hereof.

     8. PURCHASE PRICE

     The purchase price per share at which a share of Common Stock will be sold during any Offering
Period shall be eighty-five percent (85%) of the lesser of:

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	 	(a)	 	The fair market value on the Offering Date; or
	 
	 	(b)	 	The fair market value on the Purchase Date.

     For purposes of the Plan, the term “fair market value” on a given date shall mean the closing
price from the previous day’s trading of a share of the Company’s Common Stock as reported on the
National Association of Securities Dealers Automated Quotation (“Nasdaq”) System or such other
system or exchange to which the shares of the Company’s Common Stock are admitted to trading or
quotation, as determined by the Administrator.

9. PAYMENT OF PURCHASE PRICE; CHANGES IN PAYROLL DEDUCTIONS; ISSUANCE OF SHARES

     (a) The purchase price of the shares is accumulated by regular payroll deductions made during
each Purchase Period. The deductions are made as a percentage of the participant’s compensation in
one percent (1%) increments not less than one percent (1%) nor greater than fifteen percent (15%),
not to exceed $25,000 per year or such other limit set by the Administrator. Compensation shall
mean all cash compensation including, but not limited to, base salary, wages, commissions,
overtime, shift premiums and bonuses, plus draws against commissions; provided, however, that for
purposes of determining a participant’s compensation, any election by such participant to reduce
his or her regular cash remuneration under Sections 125 or 401(k) of the Code shall be treated as
if the participant did not make such election. Payroll deductions shall commence on the first
payday following the Offering Date and shall continue to the end of the Purchase Period unless
sooner altered or terminated as provided in the Plan.

     (b) A participant may decrease (but not increase) the rate of payroll deductions during a
Purchase Period by filing with the Treasury Department a new authorization for payroll deductions,
in which case the new rate shall become effective for the next payroll period commencing more than
fifteen (15) days after the Treasury Department’s receipt of the authorization and shall continue
for the remainder of the Purchase Period unless changed as described below. Such change in the rate
of payroll deductions may be made at any time during a Purchase Period, but not more than one
change may be made effective during any Purchase Period. A participant may increase or decrease the
rate of payroll deductions for any subsequent Purchase Period by filing with the Treasury
Department a new authorization for payroll deductions not later than the business day before the
beginning of such Purchase Period. An increase or decrease in a participant’s payroll deduction
does not start a new Offering Period.

     (c) All payroll deductions made for a participant are credited to his or her account under the
Plan and are deposited with the general funds of the Company. No interest accrues on the payroll
deductions. All payroll deductions received or held by the Company or a Subsidiary, respectively,
may be used by the Company or a Subsidiary, respectively, for any corporate purposes, and neither
the Company nor a Subsidiary shall be obligated to segregate such payroll deductions.

     (d) On each Purchase Date, so long as the Plan remains in effect and provided that the
participant has not submitted a signed and completed withdrawal form before that date which
notifies the Company or a Subsidiary, respectively, that the participant wishes to withdraw from
that Purchase Period under the Plan and have all payroll deductions accumulated in the account
maintained on behalf of the participant as of that date returned to the participant, the Company
shall apply the funds then in the participant’s account to the purchase of whole shares of Common
Stock reserved under the option granted to such participant with respect to the Purchase Period to
the extent that such option is exercisable on the Purchase Date. The purchase price per share shall
be as specified in Section 8 of the Plan. Any cash remaining in a participant’s account after such
purchase of shares shall be refunded to such participant in cash, without interest; provided,
however, that any amount remaining in such participant’s account on a Purchase Date which is less
than the amount necessary to purchase a full share of Common Stock of the Company shall be carried
forward, without interest, into the next Purchase Period. In the event that the Plan has been
oversubscribed, all funds not used to purchase shares on the Purchase Date shall be returned to the
participant, without interest. No Common Stock shall be purchased on a Purchase Date on behalf of
any employee whose participation in the Plan has terminated prior to such Purchase Date.

     (e) As promptly as practicable after the Purchase Date, the Company shall arrange the delivery
to each participant of a certificate representing the shares purchased upon exercise of his or her
option; provided, however, that the Administrator may deliver certificates to a broker or brokers
that hold such certificate in a street name for the benefit of each such participant.

3

 

     (f) During a participant’s lifetime, such participant’s option to purchase shares hereunder is
exercisable only by him or her. The participant will have no interest or voting right in shares
covered by his or her option until such option has been exercised. Shares to be delivered to a
participant under the Plan will be registered in the name of the participant or in the name of the
participant and his or her spouse.

10. LIMITATIONS ON SHARES TO BE PURCHASED

     (a) No employee shall be entitled to purchase stock under the Plan at a rate which, when
aggregated with his or her rights to purchase stock under all other employee stock purchase plans
of the Company or any Subsidiary, exceeds $25,000 in fair market value, determined as of the
Offering Date (or such other limit as may be imposed by the Code) for each calendar year in which
the employee participates in the Plan.

     (b) No employee shall be entitled to purchase more than the Maximum Share Amount (as defined
below) on any single Purchase Date. Not less than thirty (30) days prior to the commencement of any
Purchase Period, the Administrator may, in its sole discretion, set a maximum number of shares
which may be purchased by any employee at any single Purchase Date (hereinafter the “Maximum Share
Amount”). If a new Maximum Share Amount is set, then all participants must be notified of such
Maximum Share Amount not less than fifteen (15) days prior to the commencement of the next Purchase
Period. Once the Maximum Share Amount is set, it shall continue to apply with respect to all
succeeding Purchase Dates and Purchase Periods unless revised by the Administrator as set forth
above.

     (c) If the number of shares to be purchased on a Purchase Date by all employees participating
in the Plan exceeds the number of shares then available for issuance under the Plan, the Company
will make a pro rata allocation of the remaining shares in as uniform a manner as shall be
practicable and as the Administrator shall determine to be equitable. In such event, the Company
shall give written notice of such reduction of the number of shares to be purchased under a
participant’s option to each participant affected thereby.

     (d) Subject to the provisions of Section 9(d) hereof, any payroll deductions accumulated in a
participant’s account which are not used to purchase stock due to the limitations in this Section
10 shall be returned to the participant as soon as practicable after the end of the Purchase
Period, without interest.

11. WITHDRAWAL

     (a) Each participant may withdraw from a Purchase Period under the Plan by signing and
delivering to the Treasury Department notice on a form provided for such purpose. Such withdrawal
may be elected at any time at least fifteen (15) days prior to the end of a Purchase Period.

     (b) Upon withdrawal from the Plan, the accumulated payroll deductions shall be returned to the
withdrawn participant, without interest, and his or her interest in the Plan shall terminate. In
the event a participant voluntarily elects to withdraw from the Plan, he or she may not resume his
or her participation in the Plan during the same Purchase Period, but he or she may participate in
any Purchase Period under the Plan which commences on a date subsequent to such withdrawal by
filing a new authorization for payroll deductions in the same manner as set forth above for initial
participation in the Plan.

     (c) For an Offering Period in which a participant is enrolled, if the fair market value of the
Company’s Common Stock on the Purchase Date is less than it was on the Offering Date, the Company
will automatically enroll such participant in the subsequent Offering Period. A participant does
not need to file any forms with the Company to automatically be enrolled in the subsequent Offering
Period.

12. TERMINATION OF EMPLOYMENT

     Termination of a participant’s employment for any reason, including retirement, death or the
failure of a participant to remain an eligible employee, immediately terminates his or her
participation in the Plan. In such event, the payroll deductions credited to the participant’s
account will be returned to him or her or, in the case of his or her death, to his or her legal
representative, without interest. For purposes of this Section 12, an employee will not be deemed
to have terminated employment or failed to remain in the continuous employ of the Company in the
case of sick leave, military leave, or any other leave of

4

 

absence approved by the Administrator;
provided, however, that such leave is for a period of not more than ninety (90) days or
reemployment upon the expiration of such leave is guaranteed by contract or statute.

13. RETURN OF PAYROLL DEDUCTIONS

     In the event a participant’s interest in the Plan is terminated by withdrawal, termination of
employment or otherwise, or in the event the Plan is terminated by the Administrator, the Company
shall promptly deliver to the participant all payroll deductions credited to his or her account. No
interest shall accrue on the payroll deductions of a participant in the Plan.

14. CAPITAL CHANGES; CHANGE IN CONTROL

     Subject to any required action by the shareholders of the Company, the number of shares of
Common Stock covered by each option under the Plan which has not yet been exercised and the number
of shares of Common Stock which have been authorized for issuance under the Plan but have not yet
been placed under option (collectively, the “Reserves”), as well as the price per share of Common
Stock covered by each option under the Plan which has not yet been exercised, shall be
proportionately adjusted for any increase or decrease in the number of issued shares of Common
Stock resulting from a stock split or the payment of a stock dividend (but only on the Common
Stock) or any other increase or decrease in the number of shares of Common Stock effected without
receipt of consideration by the Company; provided, however, that conversion of any convertible
securities of the Company shall not be deemed to have been “effected without receipt of
consideration.” Such adjustment shall be made by the Administrator, whose determination shall be
final, binding and conclusive. Except as expressly provided herein, no issue by the Company of
shares of stock of any class, or securities convertible into shares of stock of any class, shall
affect, and no adjustment by reason thereof shall be made with respect to, the number or price of
shares of Common Stock subject to an option.

     In the event of a Change in Control of the Company, the Offering Periods shall terminate on
such date as determined by the Administrator and all payroll deductions on such date shall be used
to purchase such number of applicable shares of Common Stock unless otherwise provided by the
Administrator. For purposes of this Plan, “Change in Control” means a change in the ownership or
control of the Company, effected through any of the following events:

      (a) any “person,” as such term is used in Sections 13(d) and 14(d) of the Exchange Act
(other than the Company; any trustee or other fiduciary holding securities under an employee
benefit plan of the Company; or any company owned, directly or indirectly, by the
shareholders of the Company in substantially the same proportions as their ownership of
Common Stock of the Company) is or becomes, after the Effective Date (as defined in Section
25 hereof), the “beneficial owner” (as defined in Rule 13d-3 under the Exchange Act),
directly or indirectly, of securities of the Company (not including in the securities
beneficially owned by such person any securities acquired directly from the Company or its
affiliates) representing twenty-five percent (25%) or more of the combined voting power of
the Company’s then outstanding securities;

      (b) during any period of two consecutive years (not including any period prior to the
Effective Date), individuals who at the beginning of such period constitute the Board, and
any new director (other than a director designated by a person who has entered into an
agreement with the Company to effect a transaction described in clause (a), (c) or (d) of
this definition) whose election by the Board or nomination for election by the Company’s
shareholders was approved by a vote of at least two thirds (2/3) of the directors then still
in office who either were directors at the beginning of the period or whose election or
nomination for election was previously so approved, cease for any reason to constitute at
least a majority thereof;

      (c) the shareholders of the Company approve a merger or consolidation of the Company
with any other corporation, other than (A) a merger or consolidation which would result in
the voting securities of the Company outstanding immediately prior thereto continuing to
represent (either by remaining outstanding or by being converted into voting securities of the surviving entity), in combination with the ownership of any
trustee or other fiduciary holding securities under an employee benefit plan of the Company,
at least sixty percent (60%) of the combined voting power of the voting securities of the
Company or such surviving entity outstanding immediately after such merger or consolidation
or (B) a merger or consolidation effected to implement a recapitalization of the Company (or
similar transaction) in which no person acquires more than fifty percent (50%) of the
combined voting power of the Company’s then outstanding securities; or

5

 

      (d) the shareholders of the Company approve a plan of complete liquidation of the
Company or an agreement for the sale or disposition by the Company of all or substantially
all of the Company’s assets.

     The Administrator may, if it so determines in the exercise of its sole discretion, also make
provision for adjusting the Reserves, as well as the price per share of Common Stock covered by
each outstanding option, in the event that the Company effects one or more reorganizations,
recapitalizations, rights offerings or other increases or reductions of shares of its outstanding
Common Stock, or in the event of the Company being consolidated with or merged into any other
corporation.

15. NONASSIGNABILITY

     Neither payroll deductions credited to a participant’s account nor any rights with regard to
the exercise of an option or to receive shares under the Plan may be assigned, transferred, pledged
or otherwise disposed of in any way (other than by will, the laws of descent and distribution or as
provided in Section 22 hereof) by the participant. Any such attempt at assignment, transfer, pledge
or other disposition shall be without effect.

16. REPORTS

     Individual accounts will be maintained for each participant in the Plan. Each participant
shall receive promptly after the end of each Purchase Period a report of his or her account setting
forth the total payroll deductions accumulated, the number of shares purchased, the per share price
thereof and the remaining cash balance, if any, carried forward to the next Purchase Period.

17. NOTICE OF DISPOSITION

     Each participant shall notify the Company if the participant disposes of any of the shares of
Common Stock purchased in any Purchase Period pursuant to this Plan if such disposition occurs
within two years from the Offering Date or within one year from the Purchase Date on which such
shares were purchased (the “Notice Period”). Unless such participant is disposing of any of such
shares during the Notice Period, such participant shall keep the certificates representing such
shares in his or her name (and not in the name of a nominee) during the Notice Period. The Company
may, at any time during the Notice Period, place a legend or legends on any certificate
representing shares acquired pursuant to the Plan requesting the Company’s transfer agent to notify
the Company of any transfer of the shares. The obligation of the participant to provide such notice
shall continue notwithstanding the placement of any such legend on the certificates.

18. NO RIGHTS TO CONTINUED EMPLOYMENT

     Neither this Plan nor the grant of any option hereunder shall confer any right on any employee
to remain in the employ of the Company or any Subsidiary, or restrict the right of the Company or
any Subsidiary to terminate such employee’s employment.

19. EQUAL RIGHTS AND PRIVILEGES

     All eligible employees shall have equal rights and privileges with respect to the Plan so that
the Plan qualifies as an “employee stock purchase plan” within the meaning of Section 423 or any
successor provision of the Code and the related regulations. Any provision of the Plan which is
inconsistent with Section 423 or any successor provision of the Code shall, without further act or
amendment by the Company or the Administrator, be reformed to comply with the requirements of
Section 423. This Section 19 shall take precedence over all other provisions in the Plan.

20. NOTICES

     All notices or other communications by a participant to the Company under or in connection
with the Plan shall be deemed to have been duly given when received in the form specified by the
Company at the location, or by the person, designated by the Company for the receipt thereof.

6

 

21. SHAREHOLDER APPROVAL OF AMENDMENTS

     Any required approval by the shareholders of the Company shall be solicited substantially in
accordance with Section 14(a) of the Exchange Act, and the rules and regulations promulgated
thereunder. Such approval of an amendment shall be solicited at or prior to the first annual
meeting of shareholders held subsequent to the grant of an option under the Plan to an employee of
the Company. If such shareholder approval is obtained at a duly held shareholders’ meeting, it must
be obtained by a majority of all of the outstanding shares of the Company, or if such shareholder
approval is obtained by written consent, it must be obtained by a majority of all shareholders of
the Company; provided, however, that approval at a meeting or by written consent may be obtained by
a lesser degree of shareholder approval if the Administrator determines, in its discretion after
consultation with the Company’s legal counsel, that such lesser degree of shareholder approval will
comply with all applicable laws and will not adversely affect the qualification of the Plan under
Section 423 of the Code or Rule 16b-3 promulgated under the Exchange Act (“Rule 16b-3”).

22. DESIGNATION OF BENEFICIARY

     (a) A participant may file a written designation of a beneficiary who is to receive any shares
and cash, if any, from the participant’s account under the Plan in the event of such participant’s
death subsequent to the end of a Purchase Period but prior to delivery to him or her of such shares
and cash. In addition, a participant may file a written designation of a beneficiary who is to
receive any cash from the participant’s account under the Plan in the event of such participant’s
death prior to a Purchase Date.

     (b) Such designation of beneficiary may be changed by the participant at any time by written
notice. In the event of the death of a participant and in the absence of a beneficiary validly
designated under the Plan who is living at the time of such participant’s death, the Company shall
deliver such shares or cash to the executor or administrator of the estate of the participant, or
if no such executor or administrator has been appointed (to the knowledge of the Company), the
Company, in its discretion, may deliver such shares or cash to the spouse or to any one or more
dependents or relatives of the participant, or if no spouse, dependent or relative is known to the
Company, then to such other person as the Company may designate.

23. CONDITIONS UPON ISSUANCE OF SHARES; LIMITATION ON SALE OF SHARES

     Shares shall not be issued with respect to an option unless the exercise of such option and
the issuance and delivery of such shares pursuant thereto shall comply with all applicable
provisions of law, domestic or foreign, including, without limitation, the Securities Act of 1933,
as amended, the Exchange Act, the rules and regulations promulgated thereunder, and the
requirements of any stock exchange upon which the shares may then be listed, and shall be further
subject to the approval of counsel for the Company with respect to such compliance.

24. APPLICABLE LAW

     The Plan shall be governed by the substantive laws (excluding the conflict of laws rules) of
the State of California.

25. AMENDMENT OR TERMINATION OF THE PLAN

     This Plan shall be effective April 23, 2001 (the “Effective Date”), subject to approval by the
shareholders of the Company within twelve (12) months after the date the Plan is adopted by the
Board and the Plan shall continue until the earlier to occur of termination by the Administrator,
issuance of all of the shares of Common Stock reserved for issuance under the Plan, or ten (10)
years from the adoption of the Plan by the Board. No purchase of shares of Common Stock pursuant to
the Plan shall occur prior to such shareholder approval.

     The Administrator may at any time amend or terminate the Plan, except that any such
termination cannot affect options previously granted under the Plan, nor may any amendment make any
change in an option previously granted which would adversely affect the right of any participant
without such participant’s consent, nor may any amendment be made without approval of the
shareholders of the Company obtained in accordance with Section 21 hereof within 12 months of the
adoption of such amendment (or earlier if required by Section 21) if such amendment would:

7

 

     (a) increase the number of shares that may be issued under the Plan;

     (b) change the designation of the employees (or class of employees) eligible for
participation in the Plan; or

     (c) constitute an amendment for which shareholder approval is required in order to
comply with Rule 16b-3 (or any successor rule) of the Exchange Act.

8

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