Document:

EXHIBIT 10.12

                            EIGHTH AMENDMENT TO LEASE

     THIS AGREEMENT,  made and entered into this 18th day of November,  1998, by
and between  Newmarket  Partners III,  Limited,  a Georgia Limited  Partnership,
whose general partners are Laing Properties,  Inc. and Laing Management  Company
(hereinafter  called  "Landlord")  and  Cryolife,  Inc.,  a Florida  corporation
(hereinafter called "Tenant").

                                WITNESSETH THAT:

     WHEREAS,  Landlord and Tenant entered into a certain Lease  Agreement dated
February 13, 1986, as amended April 7, 1986, May 15, 1987, June 22, 1988,  April
4,  1989,  October  15,  1990,  March 14,  1995 and May 15,  1996  (collectively
hereinafter "Lease") for Suites 122 through 150 (hereinafter "Premises") at 2211
Newmarket Parkway, Building 8, Marietta, Georgia 30067.

     WHEREAS, Tenant desires to extend the Term of the Lease; and

     WHEREAS,  Landlord and Tenant  desire to amend the Lease in order to modify
some of the other terms and conditions of the Lease;

     NOW,   THEREFORE,   in  consideration  of  the  mutual  agreements  of  the
undersigned and other good valuable consideration, this Lease is hereby amended,
effective December 1, 1999 as follows:

48. BROKER DISCLOSURE

     Pursuant  to Georgia  Real Estate  Commission  Regulation  520-1-08,  Laing
     Marketing  Company makes the following  disclosures  concerning  this Lease
     transaction:

     a)   In this transaction,  Laing Marketing Company represents  Landlord and
          not Tenant.

     b)   In this transaction,  Richard Bowers and Company represents Tenant and
          not Landlord.

     c)   In this  transaction,  both Laing Marketing Company and Richard Bowers
          and  Company   shall   receive   their   compensation   from  Landlord
          exclusively.

     Both  Tenant  and  Landlord  acknowledge,  agree  with and  consent  to the
     representation and compensation disclosed above.

49. Paragraph 2, Term, of the Lease shall be amended to read:

     To have and to hold the same for the term to  commence  on December 1, 1999
     and ending on the 30th day of November,  2001,  at midnight  unless  sooner
     terminated as hereinafter provided.

50. Paragraph 3, Rental, of the Lease shall be amended to read:

     The Tenant agrees to pay to the Landlord  promptly on the first day of each
     month in  advance,  during  the term of this  Lease,  a  monthly  rental as
     follows:

          December 1, 1999  through  November  30, 2000 @  $14,849.84  per month
          December 1, 2000 through November 30, 2001 @ $15,295.33 per month

     Payments  received  after the tenth  day of the  month may be  assessed  an
     additional  five  percent  (5%)  charge as agreed  liquidated  damages  due
     Landlord. Acceptance by Landlord of a rental payment in an amount less than
     that which is currently due shall in no way affect  Landlord's rights under
     this Lease and in no way be an accord and satisfaction.

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Page 2 of Eighth  Amendment  to Lease by and  between  Newmarket  Partners  III,
Limited,  a  Georgia  Limited  Partnership,  whose  general  partners  are Laing
Properties,  Inc. and Laing  Management  Company and  Cryolife,  Inc., a Florida
corporation, dated November 18, 1996.

51. RENEWAL OPTION

     A.   Tenant shall have the right to renew this Lease for one (1) additional
          term of one (1) year  commencing  on December 1, 2001 (such term being
          hereinafter  referred to as the "Renewal  Lease Term").  Said right of
          renewal  shall  be  subject,  however,  to  the  following  conditions
          precedent:

          1.   Tenant shall give Landlord written notice of its exercise of such
               renewal option at least six (6) months, but no more than nine (9)
               months, prior to the expiration of the Term;

          2.   Tenant shall not have been in default in  performance  of or with
               respect to any of the terms,  covenants,  and  conditions  of the
               Lease with  respect  to any matter as to which  notice of default
               has,  if  required,  been  given and which has not been  remedied
               within the time provided by the Lease; and

          3.   In  no  event  shall  such  renewal  rights  be  granted  to  any
               subtenant(s) or assignee(s) of Tenant.

     B.   All of the  terms,  covenants  and  conditions  of  this  Lease  shall
          continue  in full force and  effect  during the  Renewal  Lease  Term,
          except that the monthly rental shall be as follows:

               December  1, 2001  through  November  30, 2002 @  $15,754.19  per
               month.

          Except as herein amended,  all terms and conditions of the Lease shall
          remain in full force and effect.

     IN  WITNESS  WHEREOF,  the  parties  hereunto  have  executed  this  Eighth
Amendment to Lease as of the day and year first above written.

Signed, sealed and delivered     LANDLORD:  NEWMARKET  PARTNERS III, LIMITED,
in the presence of:              a  Georgia Limited  Partnership, whose  general
                                 partners  are Laing Properties, Inc. and
                                 Laing Management Company

                                 BY:  LAING PROPERTIES, INC.
                                      MANAGING GENERAL PARTNER

/s/ Felicia E. Trott             BY:/s/ Albert E. Heacox
---------------------------         ----------------------------------------
Witness

                                 TITLE:V.P. Laboratory Operations
                                       -------------------------------------

s/ Suzanne K. Gabbert            ATTEST:/s/ Ed B. Cordell
---------------------------             ------------------------------------
Notary Public

                                 TITLE:VP Finance
                                       -------------------------------------
Notary Public, Cobb County,                   (CORPORATE SEAL)
Georgia

My Commission Expires
Sept. 13, 2000

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Page 3 of Eighth  Amendment  to Lease by and  between  Newmarket  Partners  III,
Limited,  a  Georgia  Limited  Partnership,  whose  general  partners  are Laing
Properties,  Inc. and Laing  Management  Company and  Cryolife,  Inc., a Florida
corporation, dated November 18, 1996.

Signed, sealed and delivered     TENANT:  CRYOLIFE, INC., a Florida
in the presence of:                       corporation

/s/ Felicia E. Trott             BY:/s/ Albert E. Heacox
---------------------------         ---------------------------------------
Witness

                                 TITLE:V.P. Laboratory Operations
                                       ------------------------------------

/s/ Suzanne K. Gabbert           ATTEST:/s/ Ed B. Cordell
---------------------------             -----------------------------------
Notary Public

                                 TITLE:VP Finance
                                       ------------------------------------
Notary Public, Cobb County,                  (CORPORATE SEAL)
Georgia

My Commission Expires
Sept. 13, 2000

Signed, sealed and delivered     LANDLORD:  NEWMARKET PARTNERS III,
in the presence of:              LIMITED, a Georgia Limited Partnership
                                 whose general partners are Laing Properties,
                                 Inc. and Laing Management Company

                                 BY:  Laing Properties, Inc.
                                      Managing General Partner

                                 BY:/s/James A. Gillespie
---------------------------         --------------------------------------
Witness

                                 TITLE:      V.P.
                                       -----------------------------------
/s/ Julie J. Waller
---------------------------
Notary Public
                                 ATTEST:     /s/ Robert R. Stubbs
                                        ----------------------------------

                                 TITLE:      Vice President & Secretary
                                       -----------------------------------

                                           (CORPORATE SEAL)
1545699v1EXHIBIT 10.13

                            NINTH AMENDMENT OF LEASE

     THIS NINTH AMENDMENT OF LEASE ("Ninth  Amendment") is made on July 25, 2001
between  TRIZECHAHN  CENTERS INC., a California  corporation,  d/b/a "TrizecHahn
Newmarket  1 to 8",  f/k/a  FASHION  PLACE  ASSOCIATES,  LTD.,  a  Utah  limited
partnership, d/b/a "TrizecHahn Newmarket 1 to 8 Management" ("Landlord"),  whose
address is 100 Colony Square,  Suite 600, 1175 Peachtree Street,  N.E., Atlanta,
GA 30361 and CRYOLIFE, INC., a Florida corporation ("Tenant").

                                    RECITALS

     This Ninth Amendment is based upon the following recitals:

     A.  Newmarket   Partners  III,  Laing  Properties,   Inc.  General  Partner
("Newmarket  III"),  as landlord and Tenant  entered into a Lease dated February
13, 1986  ("Lease"),  for the premises known as Suites  134-144  located at 2211
Newmarket Parkway, Marietta, GA 30067 ("Premises").

     B.  Newmarket III and Tenant  amended the Lease by Amendment to Lease dated
April 7, 1986;  Amendment to Lease dated May 15, 1987; Second Amendment to Lease
dated June 22,  1988;  Third  Amendment  to Lease  dated  April 4, 1989;  Fourth
Amendment to Lease dated April 2, 1990;  Fifth  Amendment to Lease dated October
15, 1990;  Sixth Amendment to Lease dated March 14, 1995;  Seventh  Amendment to
Lease dated May 15, 1996 and Eighth  Amendment to Lease dated  November 18, 1998
(Lease and Amendment(s) collectively, "Lease as amended").

     C.  Landlord  is  successor  in  interest to  Newmarket  III's  interest as
landlord under the Lease as amended.

     D.  Landlord  and Tenant  desire to  further  amend the Lease as amended to
extend the term and otherwise amend the Lease as amended accordingly.

     THEREFORE , in consideration of the mutual covenants and agreements  stated
in the  Lease as  amended  and  below,  and for other  sufficient  consideration
received and acknowledged by each party,  Landlord and Tenant agree to amend the
Lease as amended as follows:

     1. RECITALS. All recitals are fully incorporated.

     2. ADDRESS - NOTICES.  Landlord's address for notices as set forth in Lease
as amended shall be deleted and the following substituted therefore:

          TRIZECHAHN CENTERS INC
          c/o TrizecHahn Office Properties Inc.
          100 Colony Square, Suite 600
          1175 Peachtree Street, N.E.
          Atlanta, GA 30361
          Attention: David D. Canaday, Vice President

                                       1
<PAGE>

          with a copy to:

          TRIZECHAHN CENTERS, INC.
          c/o TrizecHahn Office Properties Inc.
          100 Colony Square
          Suite 600
          1175 Peachtree Street, N.E.
          Atlanta, GA 30361
          Attention: Lease Administrator

          and if notice of default, a copy to:

          TRIZECHAHN CENTERS INC.
          c/o TrizecHahn Office Properties Inc.
          100 Colony Square
          Suite 600
          1175 Peachtree Street, N.E.
          Atlanta, Georgia 30361
          Attention: Regional Counsel

     3.  EXTENSION  OF LEASE  TERM.  The Lease  Term for the  Premises  shall be
extended  for a twelve  (12)-month  period only,  to begin  December 1, 2001 and
expire on November 30, 2002 ("5th Extension Term").

     4. RENTAL, COMMON AREA MAINTENANCE  EXPENSES,  TAX AND INSURANCE ESCALATION
EXPENSES.  Effective during the 5th Extension Term,  Tenant's  obligation to pay
Rental,  Common  Area  Maintenance  Expenses  and Tax and  Insurance  Escalation
Expenses shall be as follows with respect to the Premises:

          A. RENTAL.  Effective during the 5th Extension Term,  Tenant shall pay
Landlord  monthly  rental in  advance  on the  first day of each  month in equal
monthly installments of $16,089.94; and

          B. COMMON AREA MAINTENANCE  EXPENSES.  Tenant shall reimburse Landlord
for the cost of Common Area Maintenance Expenses (as described in Paragraph 4 of
the Lease, "CAM") which shall be $0.80 per rentable square foot and subject to a
4% annual increase each calendar year; and

          C. TAX AND INSURANCE  ESCALATIONS  EXPENSES. In addition to Rental and
CAM,  Tenant shall continue to be responsible  for tax and insurance  escalation
expenses with respect to the entire  Premises in  accordance  with the terms and
conditions of Paragraph 13 of the Lease; however, and the base year with respect
to  determining  tax and insurance  escalation  expenses for the Premises  shall
remain the calendar year ending December 31, 2002.

     5. DELIVERY OF AND IMPROVEMENTS TO THE PREMISES. Landlord shall provide and
Tenant  shall accept the  Premises in "as-is"  condition.  No promises to alter,
remodel or improve the  Premises or Building and no  representations  concerning
the  condition of the Premises or Building  have been made by Landlord to Tenant

                                       2
<PAGE>

other than as may be expressly stated in the Lease as amended.

     6.  HOLDOVER.  Tenant  understands  that it does not have the right to hold
over at any time and  Landlord  may  exercise  any and all remedies at law or in
equity to recover possession of the Premises, as well as any damages incurred by
Landlord,  due to Tenant's failure to vacate the Premises and deliver possession
to Landlord as required by this Lease. If Tenant holds over after the expiration
of the 5th Extension Term with Landlord's prior written consent,  Tenant will be
deemed to be a tenant  from  month to month,  at a monthly  Rental,  payable  in
advance,  equal to 150% of the monthly  Rental  payable during the 5th Extension
Term,  and  Tenant  will be  bound  by all of the  other  terms,  covenants  and
agreements  of the Lease as  amended  as the same may apply to a  month-to-month
tenancy.  If Tenant holds over after the  expiration of the 5th  Extension  Term
without  Landlord's  prior  written  consent,  Tenant will be deemed a tenant at
sufferance,  at a daily Rental,  payable in advance, equal to 200% of the Rental
per day payable  during the 5th Extension  Term, and Tenant will be bound by all
of the other terms, covenants and agreements of the Lease as amended as the same
may apply to a tenancy at sufferance.

     7.  BROKERS.  Landlord and Tenant  represent  and warrant that no broker or
agent negotiated or was  instrumental in negotiating or consummating  this Ninth
Amendment  except  TrizecHahn  Colony Square GP LLC and Richard Bowers & Company
("Brokers"). Neither party knows of any other real estate broker or agent who is
or might be entitled to a commission or  compensation  in  connection  with this
Ninth  Amendment.   Pursuant  to  Georgia  Real  Estate  Commission   Regulation
520-1-108,  TrizecHahn  Colony  Square GP LLC  hereby  discloses  the  following
concerning  this  lease  transaction:   (1)  TrizecHahn  Colony  Square  GP  LLC
represents  Landlord  and not Tenant;  (2) Richard  Bowers & Company  represents
Tenant  and not  Landlord;  and (3) both  TrizecHahn  Colony  Square  GP LLC and
Richard Bowers & Company shall receive their compensation from Landlord.  Tenant
and Landlord will  indemnify and hold each other  harmless from all damages paid
or incurred by the other resulting from any claims asserted against either party
by brokers or agents claiming through the other party.

     8.  CONFLICTING  PROVISIONS.  If any  provisions  of this  Ninth  Amendment
conflict with any of those of the Lease as amended,  then the provisions of this
Ninth Amendment shall govern.

     9. REMAINING LEASE  PROVISIONS.  Except as stated in this Ninth  Amendment,
all other viable and applicable  provisions of the Lease as amended shall remain
unchanged and continue in full force and effect throughout the Lease Term.

     10.  BINDING  EFFECT.  Landlord and Tenant  ratify and confirm the Lease as
amended and agree that this Ninth  Amendment shall bind and inure to the benefit
of the parties, and their respective successors,  assigns and representatives as
of the date first stated.

                  -- signatures appear on the following page--

                                       3
<PAGE>

     AFFIRMING  THE ABOVE,  the parties have  executed  this Ninth  Amendment of
Lease on the date first stated.

WITNESSES                             LANDLORD TRIZECHAHN CENTERS, INC.,
                                      a California corporation

                                      BY:  /s/
-----------------------------              -------------------------------------
                                           Robert R. Stubbs
                                           Assistant Secretar

                                       BY: /s/
-----------------------------              -------------------------------------
                                           Paul H. Layne
                                           Vice President

                                       TENANT
                                       CRYOLIFE, INC., a Florida Corporation

                                       BY:  /s/ Albert E. Heacox
-----------------------------               ------------------------------------
                                       ITS: V.P., Laboratory Operation
                                            ------------------------------------

                                       4
1545036

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