Document:

exv10w13

Exhibit 10.13

D8868

Copy to: colleagues

Number of attachments: 4 (Measurement Plan — plan “draft” — place description — settlement

Provincial Council and Authorization Delegation:

Transfer of deed: deed + only attachments 1 and 2

Transfer leasehold/building            Rep : 923

THE YEAR TWO THOUSAND AND TEN

On October twenty-nine

Before me, Katrien EERENS, associated notary in Geel, keeper of the original, en Philippe
COLSON, associated notary in Geel

HAVE APPEARED

     1. The inter-municipal service association CIPAL, public entity, residing at 2440 Geel,
Cipalstraat 1, company number VAT BE 0219.395.192, Registry Legal Entity Turnhout, founded as a
civil partnership with the commercial format of a cooperative partnership, named “CENTRUM VOOR
INFORMATIKA PROVINCIE ANTWERPEN” (Centrum for Computer science Province Antwerp), deed granted
before notary Hugo Larose, then in Antwerp, on February 13, 1979, published in the Annex to the
Belgian Official Journal of May 10, 1980 under number 980-1, approved by Royal Order of April 2,
1979; whose statutes were amended several times, and last by virtue of an extraordinary general
meeting of which a procès-verbal was drawn up by notary Alex Benijts, in Geel, on December 19,
2008, approved by order of March 13, 2009 of the Flemish government and published in the annex to
the Belgian Official Journal of April 16, 2009 under number 09055636.

     Here represented according to article 28 of the statutes by the Chairman of the Board
and another director acting together, namely:

- Mr. HELSEN Ludo Thomas Angele, Chairman of the Board, born in Berlaar on June 2, 1944, IK
590-8137605-10 RR 44.06.02-069.61, residing at 2431 Laakdal, Oude Geelsebaan 19;

appointed as director for a period of 6 years by virtue of a special general meeting dated March 16, 2007 and
appointed as Chairman of the Board by virtue of the Board dated March 16, 2007, of which an excerpt
was published in the annex to the Belgian Official Journal of May 15, following number 07070464;
and

- Mr. WAUTERS Lucien Jean Felix, Director-Secretary, born in Lot on June 19, 1949, IK
590-3729457-27, RR 49.06.19-165.36, residing at 1600 Sint-Pieters-Leeuw, Victor Nonnemansstraat
54/2;

appointed as director for a period of 6 years by virtue of the general meeting of March 16, 2007
and appointed as director-secretary by virtue of the Board dated March 16, 2007, of which an
excerpt was published in the annex to the Belgian Official Journal of May 15, following number
07070464.

     Hereinafter ‘the seller’ or ‘the transferor’.

     2. The limited liability company GENZYME FLANDERS, residing at 2440 Geel, Cipalstraat 8,
company number VAT BE 0475.955.046, Registry Legal Entity Turnhout, founded as a public limited
liability company, deed granted before notary Luc Talloen in Leuven on October 30, 2001, published
in the Annex to the Belgian Official Journal of November 17 under number 20011117-29, whose
statutes were amended several times and whose format was changed to a private company with limited
liability by virtue of an extraordinary general meeting of which a procès-verbal was drawn up by
notary Vincent Vroninks in Elsene on December 21, 2005, published in the annex to the Belgian
Official

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Journal of February 28, 2006 number 06041895, whose statutes were amended in the end by virtue of
an extraordinary general meeting of which a procès-verbal was drawn up by notary Vincent Vroninks
in Elsene on January 14, 2010, published in the annex to the Belgian Official Journal of January
25, 2010 number 10013708,

     Here represented according to article 14 of the statutes by the following manager
acting alone, without time limitation:

- Mr. HOUWEN Petrus Cornelis Gerardus, born in Nijmegen on April 16, 1967 RR 67.04.16-479.88,
residing at 1981 Hofstade, Tervuursesteenweg 142,

     Appointed as manager by virtue of the general meeting held on June 19, 2009, published in the
Annex to the Belgian Official Journal of September 28 under number 09136248, with the authority to
act independently pursuant to the decision of the extraordinary general meeting dated June 25,
2010, published in the Annex to the Belgian Official Journal of July 27, 2010 number 10112185.

     Hereinafter ‘the buyer’ or ‘the transferee’.

WITH REGARD TO THE FOLLOWING PROPERTY

City of GEEL (third section — article number 15627)

     A plot of land with administrative building, located at Cipalstraat 1, cadastred according to
the recent cadastral extract under district K numbers 68/D/part and 48/L/part, with a measured
surface area of eighty-six ares twenty-one centiares (86a 21ca).

     As the property is depicted on ‘Lot 1’ on the measurement plan dated July 1, 2010 drawn by Mr.
Guido Van Roy, his office being at 2370 Arendonk, Heirbaan 40, land surveyor expert, sworn by the
Court of First Instance in Turnhout, hereinafter “measurement plan” which remains attached
to this deed (attachment 1).

     Hereafter also called “the property”.

     Attendees declare to know the properly well and declare this description to be precise enough
to accept; they relieve each other and the notaries of including here a more detailed description.

     ORIGINS OF PROPERTY

     Foresaid property belongs to:

- the PROVINCE OF ANTWERP, lease giver

- the transferor/ seller CIPAL, lease holder

The buyer / transferee CIPAL declares to be lease holder of the property to — under larger
surface area — have obtained lease from the PROVINCE OF ANTWERP,

* partly by virtue of deed settlement leasehold (for a period of fifty years starting from December
28, 1989), granted in the presence of notary Hélène Casman, then in Antwerp on December 28, 1989,
transferred to the second mortgage office in Turnhout on December 28, 1989, book 3236 number 6;
with regard to the goods located in Geel in de Cipalstraat cadastred according to title district K
numbers 54/L, 55/C, 55/F, 55/H, 67/A, 67/C, 67/D and parts of numbers 47/A, 48/D, 54/D, 54/M en 68,
sized in total three hectares thirty-one ares five centiares (3ha 31a 05ca),

* partly by virtue of deed leasehold (for a period starting on February 9, 2001 and ending
December 27, 2039) granted before notary Marc Bogaert in Geel on February 9, 2001, transferred to
second mortgage office in Turnhout on February 15 number 77-T-15/02/2001-01262: with regard to the
goods located in Geel in de Cipalstraat cadastred according to title district K numbers 44/C, 47/C,
68/B and 69/C, size sixty-nine ares fifty centiares (69a 50ca) and district K part of number 54/P
size 2 ares seventy centiares (2a 70ca)

     GENERAL PROVISION

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The transferor/seller and the transferee/buyer explicitly agree that the hereafter mentioned “long
lease transfer” and “building sales” are dependent legal transactions that are inseparably tied to
each other.

     The attending parties request that we, the notaries to draft, after this exposition, the
public instrument of the following agreement directly convened between the two of them.

1. TRANSFER OF LONG LEASE

     The transferor, for his part (CIPAL), declares hereby that he cedes and transfers his long
lease rights to the property (granted by the ANTWERP PROVINCE) free, clear and unencumbered
by any privilege or mortgage, to the transferee (GENZYME FLANDERS) who accepts, such under the
hereafter mentioned conditions:

     The transferee thus takes from the transferor all the rights and duties that result from the
long lease granted by the ANTWERP PROVINCE to transferor CIPAL as per the hereafter mentioned
public instruments, however ONLY insofar as these relate to the described properties, subjects
of this deed:

- on one hand the deed establishing a long lease executed by notary Hélène Casman, at the time in
Antwerp on December 28, 1989: regarding the properties located at Geel, on Cipalstraat registered
in the land registry under the rubric district K, numbers 54/L, 55/C, 55/F, 55/H, 67/A, 67/C, 67/D
and parts of numbers 47/A, 48/D, 54/D, 54/M and 68, with a total area of three hectares, thirty one
ares and five centiares (3ha 31a 05ca),

- on the other hand the deed establishing a long lease executed by notary Marc Bogaert, at the
time in Geel on February 9, 2001: regarding the properties located at Geel, on Cipalstraat
registered in the land registry under the rubric district K, parts of numbers 44/C, 47/C, 68/B and
69/C with an area of sixty nine ares, fifty centiares (69a 50ca) and district K, part of number
54/P with an area of two ares, seventy centiares (2a 70ca),

     provided the following adjustments are made regarding duration, annual compensation
and enjoyments set forth below in points A), B) and C).

     ADJUSTMENT TRANSFERRED LONG LEASE

     A/REGARDING THE DURATION

      Both long leases, the one established by the aforementioned deed of notary Casman,
dated December 28, 1989 as well as the one established by the aforementioned deed of notary
Bogaert, dated February 9, 2001, were established for a term expiring on December 27, 2039.

     The terms of both long leases are hereby extended in regard to the property, subject of the
current long lease transfer, to jointly expire on June 24, 2097.

     B/REGARDING THE ANNUAL COMPENSATION/GROUND RENT.

      The annual ground rent for the real estate, subject of the current long lease
transfer is set at one euro and twenty four cents (€ 1, 24) per square meter, indexed based on the
consumer price index of October 2002 (base of 1996) (111.09) and as a new index the consumer price
index of September 2010 (base of 1996) (131.31).

     The total amount is calculated based on the surface, as indicated on property maps in the
current deed; and the rates, established by the Antwerp provincial council in the meeting of
September 23, 2010.

     The basic ground rent thus amounts to twelve thousand six hundred and thirty five euros and
seventy eight cents (€ 12,635.78).

     This basic ground rent is adjusted yearly on the expiration date of the current long lease
agreement, based on the index of consumer prices, with the new ground rent calculated by
multiplying the basic ground rent by a fraction whose denominator is equivalent to the index for
September 2010 and the numerator being equivalent to the index of the month following the
adjustment.

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     The ground rent is payable within two months of the annual expiration date. Failing payment
within the established term a late payment interest shall be owed by law and without further notice
on a yearly basis, based on the legal late payment interest calculated month of delayed payment,
with each month or fraction thereof to be counted as a full month.

     C) REGARDING ENJOYMENT:

     The transferor shall nevertheless retain the enjoyment of part of the land, subject of
the current agreement, explicitly the section indicated by hatching on the draft map, which
shall remain attached to the current deed (however, without any description) (appendix 2) to be
made freely available to the transferee the latest three years from today.

     The transferee guarantees the transferor that besides the enjoyment of the administrative
building, mentioned under 2.1 below, transferor also retains the enjoyment of 60 temporary
parking spaces near the administrative building. At present the transferor/seller uses 60
parking spaces in front of the administrative building. The transferor may continue using these as
log as the transferee has not initiated construction activities at this location. If construction
activities are initiated by transferee and, consequently, these parking spaces become wholly or
partially unavailable to the transferor then the transferee ought to provide transferor, free of
cost, “replacement visitor parking” described hereafter -to be built and paid for by
transferee.

     At any given moment there ought to exist 60 temporary parking spaces for the transferor,
either in front of the administrative building or in the “replacement visitor parking”.

     These temporary parking spaces remain available to the transferor until the last of the
following two dates:

     (i) the effective release of the administrative building by the seller;

     (ii) the moment when there are 60 permanent parking spaces available to the transferor at the
technology section in Geel, either in an underground parking garage or an above ground parking deck
near the CIPAL buildings (this date is only valid only if the transferee/buyer confirms making
available 60 permanent parking spaces, mentioned hereafter as part of price reduction).

     The application of aforementioned point (ii) may not result in transferee having to keep 60
temporary parking spaces available to the transferor for a period longer than six years from today.

     The transferee obtains enjoyment of the other grounds starting today.

     The transferor already gave permission to transferee on June 29, 2010 to execute the following
preparatory work at the responsibility of and paid for by transferee, contingent upon obtaining the
required permits:

- placing site separations as indicated on the draft map (appendix 2)

- installing a replacement visitor parking for the transferor as indicated in yellow on the draft
map (appendix 2).

     Concerning the sections of the grounds to which transferor has retained enjoyment as
aforementioned, transferor and transferee declare

- that they have previously drawn, at the expense of the buyer, a joint inventory of fixtures
and lands (through the services of an expert), an original version of which will remain affixed
to this deed in order to be registered with it (however, without description) (appendix 3).

2. SALES OF THE BUILDING

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     The seller declares hereby that he sells, cedes and transfers, subject to the usual legal
guarantees free, clear and unencumbered of any privileges and mortgages to buyer, who
accepts, the administrative building (hereafter named “building”) that is part of the previously
described realty under the hereafter mentioned conditions:

     1. Ownership-Enjoyment-Use.

     Seller shall acquire ownership of the sold building starting today through the end of
the long lease (being June 24, 2097).

     Enjoyment. Seller declares that the administrative building is used by him and will be
made available the latest 3 years from today.

     From today up to the date on which seller effectively makes the building available, seller
shall not owe buyer ANY compensation for usage. Seller may not levy rent on the property.

     Seller’s obligations during the enjoyment of the building.

      Seller and buyer declare that they have previously drawn a joint inventory of
fixtures and lands (through the services of an expert), pertaining to the administrative building
and the grounds at buyer’s expense.

     As long as the seller still has enjoyment of the administrative building he shall be
responsible for all expenses and burdens of maintenance and repair of the building which the
leaseholder is legally responsible for (costs the lessor is legally responsible for will be the
buyer’s responsibility).

     Buyer assures seller that seller may continue his activities during the enjoyment of the
administrative building without unreasonable noise nuisance. During this period buyer and seller
shall, by joint deliberation, be responsible for the continuity of activities in the administrative
building and on the site.

     Seller and buyer are not allowed to make any changes, alterations or embellishments to the
administrative building WITHOUT previous joint written agreement.

     Seller commits to fully vacate and meticulously clean the administrative building at the end
of his enjoyment (or, the latest 3 years from today).

     The risk of the property is transferred to buyer today.

     2. Burdens.

     Buyer assumes responsibility for his portion of the real estate tax as well as for the current
or contingent to be established county taxes on the sold administrative building from the initial
moment of his enjoyment of the building though use.

3. ADDITIONAL CONDITIONS OF TRANSFER/SALES

     1. Condition of the property — Dimensions.

     The transferee/buyer will accept the property (land and administrative building) in:

     -as is, as described in the aforementioned joint inventory of fixtures and lands
(aforementioned appendix 3).

     -without safeguards regarding visible or hidden defects, unmitigated by that which is
hereafter mentioned in the section titled “Soil Remediation”.

     - without safeguards regarding the indicated larger surface area; any difference, even if it
were one twentieth or more shall be to the advantage or disadvantage of the buyers, without
recourse against sellers.

     Indications on the grounds map and the draft map, referred to in describing the property, are
the responsibility of the map maker; the notaries are not responsible for this.

     The transferor/seller explicitly declares he does not know of any hidden defect that could
affect the administrative building.

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     2. Easements.

     The rights on the property and administrative building are transferred/sold with all their
suffering and prevailing, continuing and no-continuing, visible and invisible easements, with all
wall systems that may burden or favor it. Transferee/buyer is free to opposes the disadvantages and
make the advantages count for him, all of this though on his own account and at his own risk,
without the intervention of the transferor/seller nor redress against him; this is not a standard
clause but rather an explicit condition of the transfer/sale.

     Seller declares not to know of any easements which burden the transfer, except those which
could result from his ownership, and which he has personally allowed, except for what is mentioned
in both aforementioned leases dated December 28, 1989 and February 9, 2001:

“In aforementioned deed executed on March nineteenth nineteen hundred fifty seven (being a deed of
sales executed by the Antwerp province on March 19, 1957) the following is mentioned:

“In this regard it is explicitly stipulated that the sold parcels have rights of road
alongside the existing service roads marked in yellow on above mentioned map”

“The lease taker is required to comply with the obligations that result from this and is allowed to
use the rights derived therefrom to his advantage”.

     Transferee/buyer is subrogated in the rights and duties contained in the above mentioned
stipulations as far as these are still applicable to the transferred/sold property, without this
clause having the power to confer further rights to third parties than those which result from
regular an unexpired laws.

     The properties are transferred/sold free from the split grounds rights or easement of original
common ownership so they must be considered to never have belonged together with any other goods,
to one and the same owner. The Transferee/buyer declares that, together with the hereby transferred
goods and the surrounding properties two separate properties belong to him, onto which no easement
has been attached.

     3. Taxes.

     Transferee/buyer shall be responsible, from the moment of initial enjoyment, for all taxes
which the transferred/sold property is, or might eventually be burdened with.

     4. Insurance.

     Buyer declares knowing that if the sold property is insured against fire and other hazards
this insurance ends by law three months after the date of this current deed and may even expire
earlier due to the expiration of its term or other reasons.

     Buyer declares he will be responsible, starting today for get insurance for
the sold property and is appraised of the fact that seller (as owner) may cancel his current
insurance policy any day, starting today.

     Seller agrees to get insurance as a “user”, starting today until the property
is freely available to the buyer (maximum 3 years as of today)

     4. Utilities.

     Buyer is required to take over all eventual existing contracts regarding water, gas or
electricity provision for the building from the day of initial enjoyment.

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     Seller declares that the buildings Cipal A and Cipal B, as indicated on the attached map
(appendix 1) are currently dependent on each other regarding utilities. Buyer shall be responsible
for at own expense and risk for the correct turning off and installation, the latest at the moment
of initial enjoyment.

     5. Partitions and boundary.

     The rights on the property and the administrative building are also transferred/sold with all
rights and duties related to eventual walls, hedges or other fencing that divide the
transferred/sold property from adjacent properties.

     Buyer shall, at his own expense, upon initial enjoyment be responsible for placing fencing
according to the parcel boundaries of the seller as indicated on the aforementioned map (appendix
1). The hydrant, the lighting, the container storage, the underground sprinkler system and the
bicycle shed shall be moved by seller at buyer’s expense.

     The costs of shutting off of pipes, eventual security systems, parcel boundaries (this not
being an exhaustive listing) are at the transferee/buyer’s expense. Transferor/seller and
transferee/buyer agree that for the execution of these works they will consult with each other
ahead of time.

     6. Urban planning.

     1.) Seller declares that the property, subject of the current deed, is not subject to any
expropriation procedure or any measure taken in the context of the protection of Monuments and
Landscapes.

     2.) If the property happens to be fully or partially subject to expropriation, setback line
requirements, regarding front property construction and back property construction, urban planning
requirements or any government decisions or regulations, the transferee/buyer shall comply with all
prescriptions of each, without recourse against the transferor/seller for loss of land, refusal of
entry to buildings or any other reason whatsoever.

     3.) Transferor/seller declares not having any knowledge of infringements on any Urban Planning
laws that might relate to the hereby transferred/sold property. Seller states that he obtained all
the necessary legal permits for constructions made during his period of ownership. He also states
in good faith to have no knowledge of illegal constructions from before he was owner.

     4.) Executing notary and transferor/seller state, following article 5.2.1. of the Flemish Code
of Spatial Planning as evidenced in the urban planning extracts of sold/transferred properties by
the city of Geel on October 19, 2010 (for numbers 68/D and 48/L) of which buyer/transferee
acknowledges having received a copy previously:

     10 that for the real estate, the building permits/urban planning permits mentioned
hereafter are issued (according to the hereafter mentioned urban planning extract dated October 19,
2010):

     20 that the most recent urban planning destination for the property is:

*according to the EIP Technology zone approved on 03/01/2002: buffer zone, zone for public use
aimed for high level technological industry, zone for high level technological industry, public
lands,

*according to the Herentals-Mol regional plan: areas for public services and public use,

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     30 that, as is evident from the mortgage certificate and the declaration of the
seller, no summons has been served for the property according to article 6.1.1 or 6.1.41 through
6.1.43 of the Flemish Code of Spatial Planning.

     The mortgage certificate does have the following note in the margins:

77-M-21/02/2002-01280 contra CIPAL:

     “INFRINGEMENT URBAN PLANNING

     Comment

     Regards: regularization

     Preliminary certificate (art 158 of the decree from 05/18/1999 regarding the organization of
spatial planning) dated December 13, 2001, of the urban planning inspector from the Ministry of the
Flemish Community Department of Living Environment and Infrastructure in Antwerp comprising an
affirmation of payment of the transaction amount and the petition of a regularization permit for
C.V. CIPAL at Geel, in execution of a settlement proposal regarding the real estate located at
Geel, division 3, section K number 68/B and 56/A.

     This certificate does NOT affirm that the petitioner has or will have the permit nor does it
create any rights as to the getting such permit.”

     Seller/transferor, CIPAL, states hereby emphatically in regard to mentioned margin note that a
REGULARIZATION PERMIT was issued afterward, specifically on April 24, 2002 for the implanting of an
“expansion of CIPAL” and outdoor construction, mentioned further in the urban planning extract
(dossier number SV6824445).

     40 that there is no sales rights on the described property as provided in article
2.4.1 of the Flemish Code of Spatial Planning;

     50 that no parceling/allotment permit is applicable on the property,

     60 that no as-built certificate has been delivered, which is mandatory according to
article 4.2.12, § 2,20 Flemish Code SP.

     Aforementioned urban planning extract mentions, among other things, the following:

“parcel information”: land registry division: GEEL 3 div — Section K — parcel number: 68D, 48L,
48N — Land Registry type: administrative building and right of way. 

I. PLANS:

- Extraordinary installation plan (EIP): plan name: Technology zone, approval date
03/01/2002:

destination 1: buffer zone

destination 2: zone for public use aimed for high level technological industry

destination 3: zone for high level technological industry

destination 4: public lands

- Herentals-Mol regional plan (prescriptions of an RUP, EIP or allotment have priority
above the regional plan): approved on 07/28/1978: destination: areas for public services and public
use,

II. PERMITS OVERVIEW:

-dossier number SV5510861, type of works: infrastructural works technology zone.

petitioner: Province government of Antwerp, permitted on 02/19/1992, parcel 3 K 68A,

-dossier number SV3498035, type of works: expansion of existing pharmaceutical production unit,
petitioner Genzyme Flanders, permitted on 05/12/2003, parcel 3 K 44C,

-dossier number SV4206750, type of works: adaptation of the right of way, petitioner: Cipal,
permitted on 12/22/2003, parcel 3 K 68A,

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-dossier number SV14605162, type of works:modification of the outdoor constructions
of the Cipal site in Geel, status: wait on advice, parcel 3 K 68A,

-dossier number SV2408415, type of works: expansion of a production unit, petitioner Genzyme
Flanders, permitted on 09/02/2002, parcel 3 K 44C,

-dossier number SV2264418, type of works: construction of two bicycle sheds and one container
storage, petitioner CIPAL, permitted on 06/17/2002, parcel 3 K 68A,

-dossier number SV6229345, type of works: erecting a prefab High voltage boot, petitioner Antwerp
Province government, permitted on 11/13/1998, parcel 3 K 68A,

-dossier number SV 2448961, type of works: erecting pigsties and calf stables, petitioner Antwerp
Province government, permitted on 10/12/1966, parcel 3 K 68A,

-dossier number SV5427808, type of works: new construction of offices, petitioner CIPAL, permitted
on 10/28/1991, parcel 3 K 68A

-dossier number SV6029668, type of works: adaptation of right of way, petitioner CIPAL, permitted
on 10/09/2001, parcel 3 K 68A,

-dossier number SV14537970, type of works: PARKING building a temporary parking for Cipal,
petitioner Genzyme Flanders, permitted on 10/18/2010, parcel 3 K 68D,

-dossier number SV14643362, type of works: office, petitioner Cipal, permitted on 12/23/1999,
parcel 3 K 68D,

-dossier number SV5807891: type of works: new construction of three office units, petitioner INnet,
permitted on 01/31/1994, parcel 3 K 68A.

-dossier number SV6824445: type of works: regularization of changed functions, canopy, entrance
hall and implantation, petitioner CIPAL, permitted on 04/24/2002, parcel 3 K 68C,

Construction crimes: no data found,

Allotments: no data found,

Allotment changes: no data found,

Urban planning certificates: no data found,

Buildings and constructions: no data found.

III. ENVIRONMENT

-As far as is known is there an unexpired environmental permit (or ARAB-exploitation permit, or a
water discharge permit, or a permit for garbage processing or groundwater harvesting) in effect on
this property: yes,

—As far as is known is there an activity executed on the premises and/or is/was there an
establishment located there, mentioned in appendix 1 at VLAREBO: — (no answer),

-the county has a certificate for the real estate from the OVAM register of soiled grounds: no
....

V. PROTECTION OF HERITAGE PROPERTY:

-As far as is known is the property listed on a list of protected archeological monuments and/or
zones: yes, archeological zone F (zone of attention). F means it is an archeological zone of
attention and that ground disturbances require continued archeological advice during the first
planning phase.

     5.) Division: Please note that in pursuance of article 5.2.2. of the Flemish Code of Spatial
Planning undersigned notary notified the council of Mayor and Aldermen of the city of Geel per
writing of October 18, 2010 of the division which led to the current sale. She has participated at
the bottom of the aforementioned urban planning extract dated October 19, 2010:

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This petition is situated in a planning certificate, approved by deputation by the province of
Antwerp in the meeting of August 26, 2010. Regarding the division there are no remarks.

     No allotment or urban planning permits were issued for the division; there is no certainty
about the possibility to construct on the property or to erect any permanent or temporary buildings
that could be used for occupation.

     6.) Executing notary asks attention of the appearing parties for article 4.2.1. of the Flemish
Code of Spatial Planning (regarding permit mandated actions), as well as article 6.1.1., first
paragraph of aforementioned Code (sanctions for non-compliance with the duty to inform).
Transferee/buyer states, in pursuance of article 6.3.1. of aforementioned Code to renege on the
regulation of annulment based on the obligation to provide information because any eventual lack of
obligation to provide information has been corrected by the publicity and private deed (article
5.2.5. of the Code) by the current public instrument.

     7.) Woods. Transferor/seller declares that the transferred/cold property does not contain
woods and that the stipulations of the woods decree are thus not applicable to this sale.

     8.) Transferor/seller states that he agrees with the necessary destination change of the
technology zone in Geel, as shown in the planning certificate obtained by the
transferee/buyer on August 26, 2010, of which transferee/buyer recognizes having a copy in his
possession.

     7. Soil remediation.

     1.) transferor/seller declares EMPHATICALLY that the land, subject of current deed is as far
as he know not an at-risk-land. This means that there are nor did exist any risk
installations on this land, such as industrial plants, factories, warehouses, machines,
installations, equipments and activities that may entail a high risk of ground pollution according
to article 6 of the Soil Decree.

     Transferor/seller declares and confirms explicitly that risk activities mentioned in the
environmental permits issued to CIPAL (mentioned among other places in section 11.1.2., current
rubric number 11.1.10 b) were NEVER executed on the land, subject of this current deed,
being the full land registry parcel numbers 68/D and 48/L (even though the environmental permits
were eventually issued in part for these parcel numbers — as participated by the environmental
service of the city of Geel). Consequently, the transferor/seller again emphatically guarantees
that the land, subject of this current deed is not at-risk-land.

     2.) Transferor/seller states that transferee/buyer has been appraised, before closing the
original agreement, of the contents of the soil certification delivered by OVAM on May 31, 2010 in
pursuance of article 101 §1 of mentioned Decree. Each Soil certification states:

“2 Contents of the soil certification

OVAM does not have relevant data for this property regarding soil quality.

This soil certification replaces all previous certifications.

Remarks

1 At-risk-lands may only be transferred if an orientation investigation is sent beforehand to OVAM,
mentioning the transfer.

2 Additional information about the transfer regulations: www.overdracht.ovam.be.

10

 

3 If soil is excavated, taken away or received the rules earth moving apply. More information:
www.ovam.be.grondverzet.”

     3.) Transferor/seller declares, regarding the land that is subject of current deed, to being
aware of any soil pollution which may cause damage to the transferee/buyer or to third parties, or
which can provide cause for cleaning obligations, usage limitation or other measures the government
can impose in this regard.

     4.) Based on the above declarations the notary confirms that the stipulations of the soil
decree have been followed in regard to the transfer of the lands.

     5.) Insofar as the above declaration by the transferor/seller was made in good faith
transferee/buyer takes on the risks of eventual soil pollution and damage as well as the expenses
that may result from that and declares that he will absolve transferor/seller of any need for
safeguards.

     8. Post intervention dossier.

     The seller states that the property has had construction done since May 1, 2001, but that
these commenced prior to May 1, 2001, therefore the provisions of Royal Order dated January 25,
2001 regarding temporary mobile construction sites, are not applicable.

     9. Prerogative presale

     Transferor/seller declares:

a) that the transferred real estate is not listed on any inventory of levies regarding empty and
neglected buildings and residences;

b) that he was not notified or warned by administrative notice that the property shall be placed on
an inventory, except in case of profound challenge;

c) that the residence was not declared uninhabitable, that the sold property was not claimed as
meant in article 13bis of County Law and the Royal Decree of December 6, 1993,

d) the undeveloped part of the presently transferred property is not located in a region indicated
by the Flemish Government as a special region;

e) that the sold administrative building is not subject of any legal, decreed, or conventional
right of pre-emption, option renewals, preferential rights or right of re-purchase.

     10. Fuel tank.

     Transferor/seller states that there is no underground or above ground fuel tank on the
transferred property.

     11. Inspection of the electric equipment energy performance certificate.

     Not required since this is not a housing unit of a residential building.

     12. Risk zone for flooding.

     Undersigned record keeping notary declares in pursuance of article 68-7 of the Law Land
Insurance Agreement that -based on the information obtained from the website
http://geo-vlaanderen.agiv.be/geo-vlaanderen/overstromingskaarten previously described property,
subject of current deed, is not located in a flood risk zone defined by Royal Decree.

     13. Natural gas (KLIM Federal Cables and Conduits Information Center).

     Parties declare — based on the information obtained on the website
https://www.klim-cicc.be/klimnew/index.php?LG=1 — that previously described property is not located
near transportation systems for hazardous products through conduits or above ground and underground
high voltage cables.

     14. Ten-year liability.

11

 

     The transferee/buyer is simply put in the place of the transferor/seller regarding all rights
he could invoke, have had invoked or having invoked in the context of the ten-year liability
(articles 1792 and 2270 of the Civil Code). Buyer with nevertheless be held responsible, to the
full exoneration of seller, for any expenses resulting therefrom in whatever amount that may be
exacted starting today.

     15. Arbitration.

     All disputes possibly arising from this agreement will be definitively settled according to
the Arbitration Regulation of CEPINA, by one or more arbiters appointed in accordance with this
regulation.

Parties refer in this regard to http://cepani.be.

Arbitration tribunal will consist of three arbiters.

The seat for the procedure would be Brussels.

The arbitration language will be Dutch.

Applicable law will be Belgian law.

Parties that so desire, may decide that arbitration must be preceded by an attempt at mediation
(Division IV-Regulation).

COST OF TRANSFER/SALE

      Current transfer of long lease on the administrative building is allowed and
accepted for the BASE PRICE of eleven million nine thousand three hundred twenty two euros
( € 11,009,322.00), which gets adjusted as follows.

     INCREASE — not applicable.

      Aforementioned base price is increased with the rise of the construction index from
May 2010 (base index) and with the new index: the index from August 2010.

     all of this according to the following formula

     The price is adjusted according to article 13 of Standard Specification VL100 for government
transfers of contracts for construction projects CAT A, > 10 workers and according to the
formula:

p = Px (0.4 x s/S + 0.4 i/I + 0.2)

Where:

- p=adjusted price;

- P= Price, based on contract;

- s= average hourly wage of laborer the second calendar month before signing the public instrument,
augmented with % social security and insurance;

- S= same as s, average hourly wage operative in May 2010.

- i=index number, based on annual consumption of the most important materials and primary materials
in the construction business, in use in the second calendar month before signing the public
instrument;

- I=same as i, index number for May 2010.

Parties declare that for this only eventual increases need to be taken into account, not decreases.
Negative indexes are thus not taken into account.

     No decreases (negative indexes) will be taken into account. The base price will not be
adjusted in case of a decrease of the index (a negative index).

     CONDITIONAL DECREASE

      The aforementioned base price shall be decreased by one million one hundred and
ninety three thousand and five hundred euros (€ 1,193,500.00) if the following conditions have been
met:

     1.- seller receives the latest on December 31, 2010 from buyer the written confirmation that
there will be 60 parking spaces made “available” for seller (and his personnel and guests) at the
technology zone in Geel in an underground parking garage or above ground parking deck near the
CIPAL buildings for the exclusive use of seller (and his personnel and guests), such confirmation
to be given the latest 3 years from today.

12

 

     2.- these 60 parking spaces (hereafter also called “permanent” parking spaces) ought to be
use-ready the latest 3 years from today.

     If these conditions (or one of these conditions) are not met the price decrease is
definitively rescinded.

     If the availability of the “permanent parking spaces” requires investment expenses for the
seller, these are assumed by the buyer and seller shall be completely exonerated of these costs.

     These 60 definitive parking spaces remain available to the seller at least as long as seller
actually exercises the use of the seat of his activities at the technological zone in Geel.

     MODES OF PAYMENT OF PRICE/GRANTING OF DECREASE — DISCHARGE

      Executing notary establishes that the aforementioned base price of eleven million
nine thousand three hundred twenty two euros (€ 11,009,322.00) — and the deed costs — have been
paid by the transferee/buyer through a deposit from account 734-00476457-39 to account
733-3092100-61 of the executing notary.

     The amount of the eventual price decrease of one million one hundred and ninety three
thousand and five hundred euros (€ 1,193,500.00) is blocked at the office of the executing notary
(on an account listed under buyer’s name).

     The eventual price decrease will be definitively granted to buyer and the amount of the
decrease — augmented with interests — will be immediately given by the executing notary to buyer as
soon as 60 definitive parking spaces are preliminarily made available to seller, the latest 3 years
after today. Any other scenario would preclude buyer from getting the amount of the price decrease
which will be released — augmented by interest — by the executing notary to the seller.

     The transferor/seller declares having received the base price, minus aforementioned blocked
decrease, from the transferee/buyer through a transfer from the accounting of the executing notary
onto account number 091-0041660-76 (IBAN BE91 0910 0416 6076); CONSTITUTING FULL AND DEFINITIVE
SETTLEMENT, contingent upon good and timely execution.

TRANSFERORS DECLARE DISMISSAL OF MORTGAGE REGISTRAR

The Mortgage Registrar is dismissed by transferors at the time of the transfer of this deed.

EXPENSES.

     The expenses, rights and fees of this deed of transfer/sale are paid by transferee/buyer.

DECLARATION REGARDING V.A.T.

      The undersigned notary confirms having given to parties reading material about
articles 62 §2 and 73 §1 of the tax code on added value.

     When questioned about his function as tax payer regarding the tax on added value
transferor/seller has explicitly declared to be responsible for the taxes on the added value with
the sole number of 0219.395.192.

INTERVENTION OF THE ANTWERP PROVINCE

      THE ANTWERP PROVINCE has intervened in this. Their offices are at 2018 Antwerp,
Koningin Elisabethlei 22, company registration number BTW BE 0207.725.597, Legal Person Register of
Antwerp,

13

 

represented his by:

- Mr HELSEN Conrad Alfonse Gaby Franz, Deputy, born in Deurne (Antwerp) on June 7, 1961, living at
2950 Kaplan, Zilverlindendreef 2, bus 1 (id. card number 590-7216991-23 — national number
61.06.07.057-86); and

- Mrs JEUNINCKX Huguette Yolande Marina, executive secretary at the Province Administration of
Antwerp, born in Antwerp on August 17, 1962, living at 2018 Antwerp, Justitiestraat 27, bus 17 (id.
card number 590-3346509-35 — national number 62.08.17.444-16);
acting according to authorization by the Deputies in their meeting of September 2, 2010 and acting
in execution of a decision of the Provincial Council of September 23, 2010. Both the authorization
by the Deputies and the decision of the Provincial Council will be attached to the current deed as
for a certified copy, (appendix 4),

     They declare, after being appraised of the full contents of the current deed, explicitly agree
with:

- current transfer of long lease by CIPAL to GENZYME FLANDERS regarding aforementioned properties
and with the aforementioned adjustments to the transferred long lease,

- current sale of the administrative building,

- hereby explicitly discharge the mortgage registrar from taking an ex-officio registration during
the current deed for whatever reason.

TAX DECLARATION

Regarding levies of registration rights of sales -

- the fair market value of the administration building is calculated to be two million nine hundred
thousand euros (€ 2,900,000.00).

- the burden of retained enjoyment by the seller the latest 3 year from today, calculated to be
seven hundred and fifty thousand and six hundred euros (€ 750,600.00) — taking into account a
monthly rent value of the administration building of twenty thousand eight hundred and fifty euros
(€ 20,850.00) (basic ground rent indexed up to today).

For the levy of registration rights for the transfer of long lease - the:

     - burdens of the transfer are estimated to be zero percent (0%),

     - yearly ground rent is declared to be twelve thousand six hundred and thirty five euro’s and
seventy eight cents (€ 12,635.78) (basic ground rent indexed up to today).

CHOICE OF VENUE

      For this act parties choose their respective seats as their residences. The
intervening party chooses as its venue the Provincial Administration at Antwerp, Koningin
Elisabethlei 22.

MORTGAGE AUTHORIZATION

      Seller declares hereby explicitly that the sole property is not subject to any
mortgage authorization, mortgage promise nor any irreversible order to transfer the sale proceeds
to a financial institution.

FINAL STIPULATIONS.

      1. COMPETENCE.

     All parties declare having the necessary competence to execute the actions of the current deed
and are not limited by a protective measure or restriction on decision making.

     2. REFERENCE TO PREVIOUS DEEDS

     All present confirm that previous deeds which my be referred to in this current deed ought to
be considered as one unity with this deed to function together as public document.

14

 

     3. Those present recognize that the notary indicated to them the right that each party has to
freely choose another notary or to retain the services of an adviser, especially when conflicts of
interests of asymmetric clauses are concerned. Those present have declared that they do not see any
conflicts of interest and that they see all clauses included in the deed as balanced and that they
accept them on this count.

     Those present also confirm that the notary have informed them appropriately about the rights,
duties and burdens that result from the current deed and advised them in an impartial manner.

     3. [sic] The executing notary confirms that the identity of the parties was presented to him
through legal means of identification presented by the parties. The natural persons whose state
registration numbers are mentioned in this deed explicitly declare that they accept the mention of
this number in the deed and in all copies and extracts to be made from this deed.

Those present confirm that the identity information recorded in the deed are fully correct.

     4. Parties admit to each having received a draft of the current deed at least five days before
the signing of the deed, i.e. on October 19, 2010. Current deed was read aloud in its entirety
regarding the stipulations in article 12 paragraph 1 and 2 of the law of notarial practice, as well
as eventual amendments to the previously mentioned subject. Current deed was explained in its
entirety by me, notary, for the benefit of the parties.

     4. [sic] Right to the documents: fifty euros (€ 50.00).

     WHEREOF RECORD, executed in Geel, at my office, on above mentioned date and after fulfillment
of everything mentioned above, signed by parties, intervening parties and us, notaries.

(Signatures follow)

Registered in Geel, November 9, 2010, eight sheet(s), one dispatch(es). Register 5, segment 583
folio 58 section 19. received: three hundred and eighty three thousand four hundred and seventy
seven euros and twenty eight cents (€ 383,477.28). The senior inspector (signed) Tax Expert I.
Gilis.

(APPENDICES FOLLOW)

FOR IDENTICAL COPY

15exv10w36w1

EXHIBIT
10.36.1

AMENDMENT

          AMENDMENT (this “Amendment”), dated as of November 30, 2010, to the Credit
Agreement, dated as of July 14, 2006 (as amended, restated, supplemented or otherwise modified,
this “Agreement”), among GENZYME CORPORATION, a Massachusetts corporation (the “Parent
Borrower”), the SUBSIDIARY BORROWERS (the “Subsidiary Borrowers”), the several banks
and other financial institutions or entities from time to time parties to this Agreement (the
“Lenders”), the Syndication Agent, Co-Documentation Agents and Co-Agents named therein, and
JPMORGAN CHASE BANK, N.A., as administrative agent. The parties hereto agree as follows:

WITNESSETH:

          WHEREAS, the Borrower has requested that certain provisions of the Agreement be amended as set
forth herein; and

          WHEREAS, the Administrative Agent, the Issuing Bank and the Required Lenders are willing to
consent to such amendments on the terms set forth herein;

          NOW THEREFORE, in consideration of the premises and mutual covenants contained herein, the
undersigned hereby agree as follows:

          I. Defined Terms. Terms defined in the Agreement and used herein shall have
the meanings given to them in the Agreement.

          II. Amendment to Section 1.1 (Defined Terms). Subsection 1.1 of the
Agreement is hereby amended by adding the following new definition to appear in alphabetical order:

“Consolidated Total Assets”: the consolidated total asset value of the
Parent Borrower and its Subsidiaries as reported in the Parent Borrower’s most
recent annual report on Form 10-K filed with the SEC under the Securities Exchange
Act of 1934.

          III. Amendment to Section 7.5 (Disposition of Property). Section 7.5(h) of
the Agreement is hereby amended by deleting “fair market value not to exceed 15% of Consolidated
Net Worth in the aggregate” therefrom and inserting in lieu thereof “net book value not to exceed
10% of Consolidated Total Assets in any fiscal year”.

          IV. Conditions to Effectiveness of Amendment. This Amendment shall become
effective on the date on which the following conditions precedent have been satisfied or waived
(“Effective Date”):

	 	(a)	 	The Administrative Agent shall have received a duly executed
counterpart to this Amendment from the Borrower, the Administrative Agent, the
Issuing Bank and the Required Lenders under the Agreement.
	 
	 	(b)	 	The Administrative Agent shall have received payment of all of its
reasonable and documented out-of-pocket costs and expenses incurred in connection
with this Amendment, any other documents prepared in connection herewith and the
transactions contemplated hereby, including, without limitation, the reasonable
fees and disbursements of counsel to the Administrative Agent.

          V. Representations and Warranties. The Borrower hereby represents and
warrants that (a) each of the representations and warranties in Section IV of the Agreement shall
be, after giving

 

 

effect to this Amendment, true and correct in all material respects as if made on and as of
the Effective Date (unless such representations and warranties are stated to relate to a specific
earlier date, in which case such representations and warranties shall be true and correct in all
material respects as of such earlier date) and (b) after giving effect to this Amendment, no
Default or Event of Default shall have occurred and be continuing.

          VI. No Other Amendments; Confirmation. Except as expressly amended hereby,
the provisions of the Agreement and each of the other Credit Documents are and shall remain in full
force and effect.

          VII. GOVERNING LAW. THIS AMENDMENT AND THE RIGHTS AND OBLIGATIONS OF THE
PARTIES HERETO SHALL BE GOVERNED BY, AND CONSTRUED AND INTERPRETED IN ACCORDANCE WITH, THE LAW OF
THE STATE OF NEW YORK.

          VIII. Counterparts. This Amendment may be executed by one or more of the
parties hereto on any number of separate counterparts, and all of said counterparts taken together
shall be deemed to constitute one and the same instrument. This Amendment may be delivered by
facsimile transmission of the relevant signature pages hereof.

[remainder of page intentionally left blank]

2

 

          IN WITNESS WHEREOF, the undersigned have caused this Amendment to be executed and delivered by
their proper and duly authorized officers as of the day and year first above written.

	 	 	 	 	 
	 	GENZYME CORPORATION

 	 
	 	By:  	/s/ Michael S. Wyzga
 	 
	 	 	Name:  	Michael S. Wyzga 	 
	 	 	Title:  	Executive Vice President Finance, Chief
Financial Officer 	 
	 
	 	GENZYME GLOBAL S.A.R.L.

 	 
	 	By:  	/s/ Christopher Jenner
 	 
	 	 	Name:  	Christopher Jenner 	 
	 	 	Title:  	Class B Manager 	 
	 
	 	 	 
	 	By:  	                                              /s/ Nathalie Joannes
 	 
	 	 	Name:  	Nathalie Joannes 	 
	 	 	Title:  	Class A Manager 	 
	 
	 	 	 
	 	By:  	                                              /s/ Michael S. Wyzga
 	 
	 	 	Name:  	Michael S. Wyzga 	 
	 	 	Title:  	Class A Manager 	 
	 

 

 

	 	 	 	 	 
	 	JPMORGAN CHASE BANK, N.A., as Administrative 
Agent
and as a Lender

 	 
	 	By:  	/s/ Peter M. Killea
 	 
	 	 	Name:  	Peter M. Killea 	 
	 	 	Title:  	Vice President 	 
	 
	 	BANK OF AMERICA, N.A., as Syndication Agent and as 
a
Lender

 	 
	 	By:  	/s/ Zubin R. Shroff
 	 
	 	 	Name:  	Zubin R. Shroff 	 
	 	 	Title:  	Vice President 	 
	 

 

 

	 	 	 	 	 
	 	The Bank of New York Mellon

 	 
	 	By:  	/s/ Clifford A. Mull
 	 
	 	 	Name:  	Clifford A. Mull 	 
	 	 	Title:  	First Vice President 	 
	 

 

 

	 	 	 	 	 
	 	The Governor & Company of the Bank of Ireland

 	 
	 	By:  	/s/ Anne Donovan
 	 
	 	 	Name:  	Anne Donovan 	 
	 	 	Title:  	Authorised Signatory 	 
	 
	 	 	 
	 	By:  	                                              /s/ John Goggin
 	 
	 	 	Name:  	John Goggin 	 
	 	 	Title:  	Authorized Signatory 	 
	 

 

 

	 	 	 	 	 
	 	Intesa Sanpaolo S.p.A.-New York Branch

 	 
	 	By:  	/s/ Luca Sacchi
 	 
	 	 	Name:  	Luca Sacchi 	 
	 	 	Title:  	VP 	 
	 
	 	 	 
	 	By:  	                                              /s/ Francesco DiMario
 	 
	 	 	Name:  	Francesco DiMario 	 
	 	 	Title:  	FVP, Credit Manager 	 
	 

 

 

	 	 	 	 	 
	 	KBC Bank N.V.

 	 
	 	By:  	/s/ Tim Lee
 	 
	 	 	Name:  	Tim Lee 	 
	 	 	Title:  	Director 	 
	 
	 	 	 
	 	By:  	                                              /s/ S. Kurtz Barkley
 	 
	 	 	Name:  	S. Kurtz Barkley 	 
	 	 	Title:  	Managing Director 	 
	 

 

 

	 	 	 	 	 
	 	RBS Citizens, NA

 	 
	 	By:  	/s/ Cindy Chen
 	 
	 	 	Name:  	Cindy Chen 	 
	 	 	Title:  	Senior Vice President 	 
	 

 

 

	 	 	 	 	 
	 	The Royal Bank of Scotland N.V.

(formerly known as ABN AMRO Bank N.V.)

 	 
	 	By:  	/s/ Michele Costello
 	 
	 	 	Name:  	Michelle Costello 	 
	 	 	Title:  	Director 	 
	 

 

 

	 	 	 	 	 
	 	Sovereign Bank

 	 
	 	By:  	/s/ Pierre A. Desbiens
 	 
	 	 	Name:  	Pierre A. Desbiens 	 
	 	 	Title:  	AVP 	 
	 

 

 

	 	 	 	 	 
	 	WELLS FARGO BANK, N.A.

 	 
	 	By:  	/s/ Scott Santa Cruz
 	 
	 	 	Name:  	Scott Santa Cruz 	 
	 	 	Title:  	Director

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