Document:

Amendment, dated February 1, 2008, to Executive Employment Agreement

 Exhibit 10.28 
 AMENDMENT TO 
 EXECUTIVE EMPLOYMENT AGREEMENT 

THIS AMENDMENT TO EXECUTIVE EMPLOYMENT AGREEMENT (“Amendment”) is made and entered into as of the 1st day of February
2008 by and between QUINTILES TRANSNATIONAL CORP., a North Carolina corporation (the “Company”), and DENNIS B. GILLINGS, Ph.D. (“Executive”). 
 WHEREAS, the Company, Executive, and Pharma Services Holding, Inc. are parties to an Executive Employment Agreement dated September 25, 2003 (the “Employment Agreement”); 

WHEREAS, all of Pharma Services Holding, Inc.’s rights, obligations, and interests in the Employment Agreement were assigned
to the Company and assumed by the Company pursuant to an Assignment and Assumption Agreement among the Company, Executive, and Pharma Services Holding, Inc. dated March 31, 2006; and 

WHEREAS, the Company and Executive desire to amend the Employment Agreement to memorialize new compensation arrangements and a new
reimbursement rate for business use of certain aircraft and other related revisions, all as approved by the Company’s Board of Directors in December 2007. 
 NOW, THEREFORE, in consideration of the mutual covenants and agreements set forth below and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the
Company and Executive agree that the Employment Agreement shall be amended as follows: 
 1. Section 3(ii) is
amended by adding a second sentence which reads as follows: 
 For the year 2008, Executive is eligible to participate in the
Quintiles Performance Incentive Plan at a target level of one hundred fifty percent (150%) of his annual base salary; this target level may be increased or decreased in subsequent years at the discretion of the Company. Beginning with the year
2008, the Performance Incentive Plan cap shall increase to two hundred percent (200%) of target, based on Company and personal performance. 
 2. Section 3 is amended by the addition of a new subsection (xi) which shall read as follows: 
 (xi) An option to purchase One Million (1,000,000) shares of the Common Stock of the Company under the Company’s 2008 Stock Incentive Plan (“New Plan”). The option shall be fully
vested as of the date of grant with an exercise price equal to the fair market value of the Company’s Common Stock as of the date of grant and shall be granted no later than December 31, 2008. 

 3. Section 3(viii) (reimbursement for business use of aircraft) is amended to
provide that the rate of reimbursement shall be Thirteen Thousand Five Hundred and Two Dollars ($13,502) per business flight hour rather than Ten Thousand Seven Hundred Ninety-Four Dollars ($10,794) per business flight hour and to delete Exhibit A
and replace that Exhibit with the Exhibit A, Amended attached hereto indicating the revised reimbursement formula. 
 4.
Section 4(g), Sale of Pharma; Qualifying Offering, is deleted in its entirety and the following Section is inserted in lieu thereof: 
 (g) Sale of the Company: Qualifying Offering. Upon a “Qualifying Offering,” as defined in the Shareholders Agreement between the Company and certain shareholders, dated January 22,
2008 (the “Shareholders Agreement”) or upon a sale (whether effected pursuant to Section 2.4 of the Shareholders Agreement or by merger, consolidation, recapitalization, reorganization, sale of securities, sale of assets or
otherwise), in one transaction or a series of related transactions to a Person or Persons that is not a Shareholder or a Permitted Transferee or Associate (as such terms are defined in the Shareholders Agreement) of any Shareholder or of any
Permitted Transferee of any Shareholder pursuant to which such Person or Persons (together with its Affiliates) acquires (i) securities representing at least seventy-five percent (75%) of the voting power of the Common Stock of the
Company, assuming the conversion, exchange or exercise of all securities convertible, exchangeable or exercisable for or into Common Stock, or (ii) of all, or substantially all of the Company’s assets on a consolidated basis (a “Sale
of the Company”) if, at least thirty (30) days prior to the consummation thereof, Gillings or the Company (at the direction of a majority of the Board) shall have delivered to the other party a written notice that Gillings’ employment
shall not be extended beyond the consummation of such Qualifying Offering or Sale of the Company, as the case may be; or 

5. Section 5(b) is amended to effect the following changes: 

“Sale of Pharma” shall mean “Sale of the Company”; 

“stockholder” shall mean “shareholder”; 

“Majority Common Stockholders” shall mean “Majority Common Shareholders”; and 

“Stockholders Agreement” shall mean “Shareholders Agreement”. 

6. Section 6(a)(y) is deleted in its entirety and the following inserted in lieu thereof: 

(y) three (3) years following the date Gillings (or any Permitted Transferee thereof (as defined in the Shareholders
Agreement)) cease to own any equity interest in the Company or any of its subsidiaries and . 

  
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 7. Except as amended hereby, the Employment Agreement shall remain in full force and
effect and is hereby ratified and confirmed by the Company and Executive in all respects. 
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left blank] 

  
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 IN WITNESS WHEREOF, this Amendment has been duly executed as of the day and year set
forth above. 
  

					
	QUINTILES TRANSNATIONAL CORP.
		
	By:	 	 /s/ Michael Mortimer

		 	Name:	 	Michael Mortimer
		 	Title:	 	 Executive Vice President,

Global Human Resources

	
	EXECUTIVE:
	
	 /s/ Dennis B. Gillings

	Dennis B. Gillings, Ph.D.

  
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 Proposed Reimbursement for Business use of Aircraft 

Based on NetJets g V Pricing 

Exhibit A 
  

													
	 	  	Estimated
Annual
Hours	 	  	%	 	 	 	  	 
					
	 Estimated Business Hours
	  	 	700	  	  	 	77.78	% 	 		  	
	 Total Nonbusiness Hours
	  	 	200	  	  	 	22.22	% 	 		  	
		  	  
	  
	 	  	  
	  
	 	 		  	
	
                       
     Total
	  	 	900	  	  	 	100.00	% 	 		  	
		  	  
	  
	 	  	  
	  
	 	 		  	

  

																					
	All amounts from NetJets Pricing sheet	 	 	 	 	Total
Annual
Cost	 	 	 	 	 	 	 	 	 
						
	 Capital cost
	 	 	46,000,000	  	 		 				 	 Full Share Cost - New
	   
	 	$	50,000,000	  
	 Estimated Business %
	 	 	77.78	% 	 		 				 		 				 			
		 	  
	  
	 	 		 				 		 				 			
	 Business Capital Cost
	 	 	35,777,778	  	 		 				 		 				 			
	 Less residual value
	 	 	(23,253,101	) 	 		 				 	 Residual Value Estimate
	   
	 	 	65.0	% 
		 	  
	  
	 	 		 				 		 				 			
	 Business Capital Cost
	 	 	12,524,677	  	 		 				 	 Annual Market Depreciation
	   
	 	 	9.0	% 
	 Years to Amortize
	 	 	5	  	 		 				 		 				 			
	 Annual Capital Cost - Business
	 				 		 	$	2,504,935	  	 		 				 			
							
	 Annual Interest Expense
	 	 	2,394,000	  	 		 				 		 				 			
	 Estimated Business %
	 	 	77.78	% 	 		 	$	1,862,000	  	 		 				 			
		 	  
	  
	 	 		 				 		 				 			
	 Monthly Fee
	 	 	267,203	  	 		 				 	 Stated
 Monthly
 Fee
	 	 
  
  
	Assumed
 NetJets

Profit
	  
   

  
	 	 
  
  
	Adjusted
 Monthly

Fee
	  
   

  

	 Estimated Business %
	 	 	77.78	% 	 		 				 	$      296,892	 	 	10	% 	 	$	267,203	  
		 	  
	  
	 	 		 				 		 				 			
	 Business Monthly Fee
	 	 	207,824	  	 	(× 12 months)	 	 	2,493,893	  	 		 				 			
	 Per Hour Rate
	 	 	3,701	  	 	(× 700 Hours)	 	 	2,590,700	  	 	 NetJets
 Stated
 Rate
	 	 
  
  
	Assumed
 NetJets

Profit
	  
   

  
	 	 
  
  
	Adjusted
 NetJets

Rate
	  
   

  

		 				 		 	  
	  
	 	 		 				 			
		 				 		 				 	$          3,701	 	 	0	% 	 	$	3,701	  
	 Total Reimbursement
	 	$	9,451,528	  	 		 				 			
		 				 		 	  
	  
	 	 		 				 			
	 Per hour Reimb. For Business hours
	 	$	13,502	  	 		 				 			
		 				 		 	  
	  
	 	 		 				 			

 Capital Cost and Monthly Fee use NetJets 700 hours rates to reflect the cost of “empty flights” built into
NetJets rates.Agreement and Amendment, effective December 12, 2008

 Exhibit 10.29 
 AGREEMENT AND 
 AMENDMENT TO EMPLOYMENT AGREEMENT 

AGREEMENT and AMENDMENT TO EMPLOYMENT AGREEMENT, dated as of the 12th of December, 2008 (this “Amendment Agreement”),
between DENNIS B. GILLINGS, Ph.D. (“Gillings”) and QUINTILES TRANSNATIONAL CORP. (the “Company”). 
 WHEREAS, an executive employment agreement was entered into and made effective the 25th day of September, 2003, among Gillings, Pharma, and the Company (the “Employment Agreement”); and

 WHEREAS, Section 13(d) of the Employment Agreement provides that the Employment Agreement may be changed or terminated
only by a writing signed by the party against whom enforcement of any waiver, change, modification, extension, discharge or termination is sought; and 
 WHEREAS, Section 3(ix) of the Employment Agreement provides for the Company to effect, during or after Gillings employment, a modification, revision and/or termination of certain split-dollar
insurance arrangements and understandings with Gillings and/or the irrevocable life insurance trusts created by Gillings in connection therewith, as reasonably necessary or appropriate, in a manner that will ultimately result in death benefits no
less favorable to the trusts and Gillings, than those that would have been provided had such arrangements and understandings prior to the date of the Employment Agreement remained in place without change; and 

WHEREAS, the Company has previously entered into split-dollar termination agreements with J.P. Morgan Trust Company of Delaware as
trustee of certain trusts established under the Dennis B. Gillings Irrevocable Trust Agreement dated April 22, 1996, whose successor trustee under such agreement is Delaware Trust Company, N.A, (the “Policy Owner”), pursuant to which
the Company has received all of its policy interests in certain New York Life insurance policies; and 
 WHEREAS, the Company
has previously received a portion of its policy interests in certain John Hancock insurance policies held by the Policy Owner; and 
 WHEREAS, the Policy Owner has agreed to pay to the Company its remaining policy interests in such certain John Hancock insurance policies held by the Policy Owner; and 

WHEREAS, the Company has agreed to pay Gillings a lump sum amount equal to $6,000,000.00 (less applicable tax withholdings) in connection
with the termination of such split-dollar agreements and repayment to the Company by the Policy Owner of the Company’s remaining policy interests in the certain John Hancock insurance policies held by the Policy Owner; and 

WHEREAS, in consideration of the Company’s release of its collateral assignment in connection with the split-dollar agreements and
the cash payment to Gillings, the parties to this 

  
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Amendment Agreement desire to amend and modify the Employment Agreement to provide for the release of the Company and Pharma from any further obligations pursuant to Section 3(ix) of the
Employment Agreement. 
 NOW, THEREFORE, in consideration of the mutual promises made herein, the parties agree as follows:

  

	 	1.	The Company shall pay a single lump sum amount of $6,000,000.00, less applicable tax withholdings, to Gillings within 10 business days following the Effective Date of
this Amendment Agreement (as set forth below). 

  

	 	2.	Within 3 business days following the payment to Gillings of the lump sum amount of $6,000,000.00, less applicable tax withholdings, as described in the preceding
paragraph, Gillings shall cause the Delaware Trust Company, N.A., as trustee of the certain trusts established under the Dennis B. Gillings Irrevocable Trust Agreement dated April 22, 1996, to pay to the Company the Company’s remaining
full policy interests in certain John Hancock Policies (Policy Numbers 20007431, 20007423 and 20007415), and, immediately following receipt of payment of such remaining policy interests, Company shall enter into split-dollar life insurance
termination agreements with Delaware Trust Company, N.A., as trustee of such trusts in substantially the forms attached hereto, under which the Company agrees to the termination of the John Hancock split-dollar life insurance agreements upon the
full repayment to the Company by the trust of the Company’s outstanding policy interests. 

  

	 	3.	Section 3(ix) of the Employment Agreement is hereby amended by adding the following to the end thereof: 

“Notwithstanding the foregoing or the other provisions of this Agreement, effective upon the payment by the Company to Gillings of a
single lump sum amount of $6,000,000.00, less applicable tax withholdings, in connection with the execution of split-dollar life insurance termination agreements between the Company and Delaware Trust Company N.A., as trustee of certain trusts
established under the Dennis B. Gillings Irrevocable Trust Agreement dated April 22, 1996, under which the Company, in consideration of receipt of full repayment by the trustee of the Company’s policy interests under certain John Hancock
insurance policies (Policy numbers 20007431, 20007423 and 20007415), agrees to terminate such John Hancock split-dollar life insurance agreements, all parties to this Agreement agree that the Company and Pharma shall be deemed to have satisfied all
obligations to Gillings pursuant to this Section 3(ix) of the Agreement and Gillings hereby releases Pharma and the Company from any and all further obligations and waives any and all claims against the Company and Pharma with respect to this
Section 3(ix) of the Agreement and the split-dollar life insurance arrangements and understandings.” 
 The Effective Date of this
Amendment Agreement shall be December 12, 2008. 

  
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 This Amendment Agreement may be executed simultaneously in two or more counterparts, each of which shall be
deemed an original, but all of which shall constitute one and the same instrument. 
 IN WITNESS WHEREOF, the undersigned
individual has executed this Agreement under seal by adopting the word “SEAL” beside his name and the undersigned corporation has executed this Agreement under seal through its duly authorized officers as of the day and year first above
written. 
  

					
	 /s/ Dennis B. Gillings

	Dennis B. Gillings, Ph.D.
	
	QUINTILES TRANSNATIONAL CORP.
		
	By:	 	 /s/ Michael Mortimer

  
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