Document:

Form of Bridge Warrant

 Exhibit 4.13 
 THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 OR THE SECURITIES LAWS OF ANY STATE AND MAY NOT BE SOLD OR OTHERWISE DISPOSED OF EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER SUCH ACT AND APPLICABLE
STATE SECURITIES LAWS OR AN OPINION OF COUNSEL REASONABLY ACCEPTABLE TO THE COMPANY TO THE EFFECT THAT THE TRANSACTION PURSUANT TO WHICH SUCH WARRANTS WILL BE OFFERED FOR SALE OR OTHERWISE DISPOSED OF IS SUBJECT TO AN APPLICABLE EXEMPTION TO THE
REGISTRATION REQUIREMENTS OF SUCH ACT OR SUCH LAWS. 
 WARRANT TO PURCHASE 
 SHARES OF COMMON STOCK, 
 PAR VALUE $.001 PER SHARE, 
 OF 
 PRECISION THERAPEUTICS, INC. 
 This certifies that, for good and valuable consideration, [Investor Name] (the “Warrantholder”), is entitled to purchase from Precision
Therapeutics, Inc., a corporation incorporated under the laws of the State of Delaware (the “Corporation”), subject to the terms and conditions hereof, at any time at or after the Issue Date (as defined herein) and before 5:00 P.M.,
Pittsburgh, PA time on the Expiration Date (as defined herein), the Exercise Number (as defined herein) of fully paid and non-assessable shares of Common Stock, par value $.001 per share, of the Corporation at the Exercise Price (as defined herein).

 ARTICLE I 
 Section 1.01: Definition of Terms. As used in this Warrant, the following capitalized terms shall have the following respective meanings: 
  

	 	(a)	Business Day: A day other than a Saturday, Sunday or other day on which banks in the Commonwealth of Pennsylvania are authorized by law to remain closed.

  

	 	(b)	Common Stock: Common Stock, $.001 par value per share, of the Corporation. 

  

	 	(c)	Common Stock Equivalents: Securities that are convertible into, or exercisable or exchangeable for shares of Common Stock. 

	 	(d)	Exercise Number: [Number of Exercise Shares] 

 The
Exercise Number shall be subject to adjustment in accordance with Article III. 
  

	 	(e)	Exercise Price: $0.10. 

  

	 	(f)	Expiration Date: 5:00 P.M., Pittsburgh, PA time, on the tenth anniversary of the Issue Date. 

  

	 	(g)	Issue Date: August 22, 2003. 

  

	 	(h)	Notes: The Convertible Promissory Notes due December 31, 2004 of the Corporation issued under the Loan Agreement. 

  

	 	(i)	Person: An individual, partnership, joint venture, corporation, trust, unincorporated organization or government of any department or agency thereof.

  

	 	(j)	Loan Agreement shall mean the Loan Agreement, dated April 7, 2003, by and between the Corporation, the Warrantholder and certain other parties thereto.

  

	 	(k)	Sale of the Corporation: A consolidation or merger of the Corporation with or into any other corporation or corporations, or a sale, conveyance or disposition of all or
substantially all of the assets of the Corporation pursuant to an arms-length transaction. 

  

	 	(1)	Warrant Shares: Shares of Common Stock purchased or purchasable upon exercise of this Warrant. 

 ARTICLE II 
 DURATION AND EXERCISE OF WARRANT 
 Section 2.01: Duration of Warrant. The Warrantholder may exercise this Warrant at any time and from time to time after the Issue Date,
and before 5:00 P.M., Pittsburgh, PA time, on the Expiration Date. If this Warrant is not exercised on or prior to the Expiration Date, it shall become void, and all rights and obligations hereunder shall thereupon cease. 
 Section 2.02: Exercise of Warrant. 
 (a) The Warrantholder may exercise this Warrant, in whole or in part, by presentation and surrender of this Warrant to the Corporation at its principal corporate office or at the office of its stock transfer agent, if
any, with the subscription form attached hereto as Exhibit A (the “Subscription Form”) duly executed and accompanied by payment of the full Exercise Price for each Warrant Share to be purchased. Payment of the Exercise Price shall be made
in cash. 
  

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 (b) In lieu of payment of the Exercise Price pursuant to the preceding paragraph, the Warrantholder shall
have the right to require the Corporation to convert the Warrants, in whole or in part and at any time or times (the “Conversion Right”), into shares of Common Stock by surrendering to the Corporation the certificate or certificates
evidencing the Warrant to be converted with the form of notice of conversion attached hereto as Exhibit B duly filled in and signed. Upon exercise of the Conversion Right, the Corporation shall deliver to the Warrantholder (without payment by the
holder of the Warrant of any Exercise Price) that number of shares of Common Stock which is equal to the quotient obtained by dividing (x) the value of the number of Warrants being converted at the time the Warrants are converted (determined by
subtracting the aggregate Exercise Price for all such Warrants immediately prior to the conversion of the Warrants from the aggregate Current Market Price (as defined in Section 2.05) of that number of Warrant Shares purchasable upon exercise
of such Warrants immediately prior to the conversion of the Warrants (taking into account all applicable adjustments pursuant to Article III) by (y) the Current Market Price of one share of Common Stock immediately prior to the conversion of
the Warrants. 
 (c) Upon receipt of this Warrant with the Subscription Form duly executed and accompanied by payment of the aggregate
Exercise Price for the Warrant Shares for which this Warrant is then being exercised (or by exercise of the Conversion Right), the Corporation shall cause to be issued certificates for the total number of whole shares of Common Stock for which this
Warrant is being exercised in such denominations as are requested for delivery to the Warrantholder registered in the name of the Warrantholder or its nominee, and the Corporation shall thereupon deliver such certificates to the Warrantholder. The
Warrantholder shall be deemed to be the holder of record of the shares of Common Stock issuable upon such exercise, notwithstanding that the stock transfer books of the Corporation shall then be closed or that certificates representing such shares
of Common Stock shall not then be actually delivered to the Warrantholder. 
 (d) In case the Warrantholder shall exercise this Warrant (or
exercise the Conversion Right) with respect to less than all of the Warrant Shares that may be purchased under this Warrant, the Corporation shall execute a new warrant in the form of this Warrant for the balance of such Warrant Shares and deliver
such new warrant to the Warrantholder. 
 (e) The Corporation shall pay any and all stock transfer and similar taxes which may be payable in
respect of the issue of any Warrant Shares to the Warrantholder. 
 Section 2.03: Reservation of Shares. The Corporation
hereby agrees that it will use its best efforts so that at all times there shall be reserved for issuance and delivery upon exercise of this Warrant such number of shares of Common Stock from time to time issuable upon exercise of this Warrant.

 Section 2.04: Listing. Prior to the issuance of any shares of Common Stock upon exercise of this Warrant, the
Corporation shall secure the listing of such shares of Common Stock upon each national securities exchange or automated quotation system, if any, upon which shares of Common Stock are then listed (subject to official notice of issuance upon exercise
of this Warrant) and shall maintain, so long as any other shares of Common Stock shall be so listed, such listing of all shares of Common Stock from time to time issuable upon the exercise of this Warrant. 
  

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 Section 2.05: Current Market Price. For the purpose of any computation under this
Section, the current market price (the “Current Market Price”) per share of Common Stock of the Corporation (the “Applicable Share”) on any date shall be the daily closing price of such Applicable Share on the
principal national securities exchange, on which the Applicable Shares are listed or admitted to trading or, if the Applicable Shares are not so listed, the closing asked price of such Applicable Shares on the NASDAQ National Market System if the
Applicable Shares are quoted thereon. If, on any date on which computation of the Current Market Price is to be made hereunder, the Applicable Shares are not so listed or quoted on a national securities exchange or the NASDAQ National Market System,
the Current Market Price shall be determined in good faith by the Board of Directors, or, if such Warrantholder disputes such determination, the Current Market Price shall be determined by an Independent Financial Expert in accordance with
Section 2.06. 
 Section 2.06: Independent Financial Expert. To the extent that the Current Market Price is required
to be determined in accordance with the last sentence of Section 2.05, an independent appraisal firm or investment bank experienced in the valuation of such securities and which is not affiliated with the Warrantholder (the “Independent
Financial Expert”) shall be selected in good faith by the Warrantholder exercising the Conversion Right and approved by the Corporation (excluding those directors affiliated with the Warrantholder exercising the Conversion Right), which
approval shall not be unreasonably withheld or delayed. If the Corporation and the Warrantholder exercising the Conversion Right are unable to agree on the selection of an independent appraiser within 30 days of the date when the Warrantholder
exercising the Conversion Right first delivered notice in writing to the Corporation of the name of a proposed independent appraiser, then the Warrantholder exercising the Conversion Right may request the President of the American Arbitration
Association to appoint an independent appraiser and such appointment shall be final and binding for purposes of determination of the Current Market Price in question. The Independent Financial Expert shall determine the Current Market Price. The
determination of the Current Market Price for the Applicable Share by the Independent Financial Expert as of the date of determination shall mean the price that a willing buyer would pay to a willing seller for the Applicable Share in an arm’s
length transaction, with neither party being under any immediate obligation or need to consummate the transaction, it being understood that the buyer and seller in arriving at such price in determining the value of the Applicable Share would each
consider, among other factors: (a) the past and prospective earnings of the Corporation; (b) the initial public offering value of the Corporation if shares of Common Stock of the Corporation were to be offered to the public in a widely
distributed initial public offering and listed on one or more major stock exchanges or quoted on the NASDAQ National Market; (c) comparable stock market valuations assuming such shares of Common Stock were publicly traded and widely
distributed; and (d) the value of the Corporation in connection with an auction of the Corporation as a going concern; provided that such valuation shall exclude any minority discount or discount for lack of liquidity. The Corporation
shall furnish to the Independent Financial Expert all reasonably available information requested by the Independent Financial Expert. The Current Market Price established by the Independent Financial Expert shall be final and binding with respect to
each Conversion Right. The Corporation and Warrantholder shall split all fees and expenses of the Independent Financial Expert. 
  

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 ARTICLE III 
 ADJUSTMENT OF SHARES OF COMMON STOCK 
 PURCHASABLE 
 The number and kind of Warrant Shares shall be subject to adjustment from time to time upon the happening of certain events as provided in this Article
III. 
 Section 3.01: Mechanical Adjustments. 
 (a) In case the Corporation shall at any time or from time to time after the date hereof (i) pay any dividend, or make any distribution, on the
outstanding shares of Common Stock (or Common Stock Equivalents) in shares of Common Stock, (ii) subdivide the outstanding shares of Common Stock, (iii) combine the outstanding shares of Common Stock into a smaller number of shares or
(iv) issue by reclassification of the shares of Common Stock any shares of capital stock of the Corporation, then and in each such case, the number and type of Warrant Shares into which this Warrant is exercisable immediately prior to such
event or the record date therefor, whichever is earlier, shall be adjusted so that the Warrantholder shall be entitled to receive the number and type of shares of Common Stock which such Warrantholder would have owned or have been entitled to
receive after the happening of any of the events described above, had such Warrant been converted into Common Stock immediately prior to the happening of such event or the record date therefor, whichever is earlier. An adjustment made pursuant to
this Section 3.01 (a) shall become effective (x) in the case of any such dividend or distribution, immediately after the close of business on the record date for the determination of holders of shares of Common Stock entitled to receive
such dividend or distribution, or (y) in the case of such subdivision, reclassification or combination, at the close of business on the day upon which such corporate action becomes effective. 
 (b) If the Corporation shall take a record of the holders of its Common Stock for the purpose of entitling them to receive a dividend or other
distribution and shall thereafter, and before such dividend or distribution is paid or delivered to stockholders entitled thereto, legally abandon its plan to pay or deliver such dividend or distribution, then no adjustment in the number of Warrant
Shares then in effect shall be made by reason of the taking of such record, and any such adjustment previously made as a result of the taking of such record shall be reversed. 
 (c) As used in this Section 3.01 the term “Common Stock” shall mean and include the Corporation’s authorized Common Stock, par
value $.001 per share, as constituted on the date hereof, and shall also include any capital stock of any class of the Corporation thereafter authorized which shall neither be limited to a fixed sum or percentage in respect of the rights of the
holders thereof to participate in dividends nor be entitled to a preference in the distribution of assets upon the voluntary or involuntary liquidation, dissolution or winding up of the Corporation. 
  

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 (d) In the case of a Sale of the Corporation or a proposed reorganization of the Corporation or a
proposed reclassification of the capital stock of the Corporation (except a transaction for which provision for adjustment is otherwise made in this Section 3.01), the Warrant shall thereafter be exerciseable into the number of shares of stock
or other securities or property to which a holder of the number of shares of Common Stock of the Corporation deliverable upon exercise of such Warrant would have been entitled upon such Sale of the Corporation, reorganization or reclassification;
and, in any such case, appropriate adjustment shall be made in the application of the provisions, herein set forth with respect to the rights and interest thereafter of the holders of the Warrant, to the end that the provisions set forth herein
(including provisions with respect to changes in and other adjustments of the applicable number of shares of stock issuable upon exercise) shall thereafter be applicable, as nearly as reasonably may be, in relation to any shares of stock or other
property thereafter deliverable upon the exercise of the Warrant. 
 (e) Whenever the number of Warrant Shares issuable upon exercise of this
Warrant is adjusted pursuant to paragraphs (a), (d) or (h) of this Section 3.01, the Exercise Price shall simultaneously be adjusted by multiplying the initial Exercise Price by a fraction, the numerator of which shall be the number
of Warrant Shares initially issuable upon exercise of the Warrant (as set forth on the front page of this Warrant) by the number of Warrant Shares issuable under this Warrant, as adjusted. Notwithstanding anything in this Section 3.01 to the
contrary, the Exercise Price shall not be reduced to less than the then existing par value of the Common Stock as a result of any adjustment made hereunder. 
 (f) No adjustment in the number of Warrant Shares shall be required unless such adjustment would require an increase or decrease of at least one Warrant Share; provided, however, that any adjustments which by reason
of this paragraph (f) are not required to be made shall be carried forward and taken into account in any subsequent adjustment. All calculations under this Section 3.01 shall be made to the nearest one-thousandth of a share, as the case
may be. 
 (g) In the event that at any time, as a result of any adjustment made pursuant to Section 3.01(a), the Warrantholder
thereafter shall become entitled to receive any shares of capital stock of the Corporation other than Common Stock, thereafter the number of such other shares so receivable upon exercise of any Warrant shall be subject to adjustment from time to
time in a manner and on terms as nearly equivalent as practicable to the provisions with respect to the Common Stock contained in Section 3.01(a). 
 (h) If any corporate action shall occur as to which the provisions of this Section 3.01 are not strictly applicable but as to which the failure to make any adjustment would adversely affect the purchase rights or
value represented by the Warrants in accordance with the essential intent and principles of such Section 3.01 (which are to place the Warrantholder in a position as nearly equal as possible to the position the Warrantholder would have occupied
had the Warrantholder purchased shares of Common Stock on the 

  

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date hereof), then, in each such case, the Corporation shall appoint a firm of independent certified public accountants (which may be the regular auditors of
the Corporation) to give their opinion upon the adjustment, if any, on a basis consistent with the essential intent and principles established in this Section 3.01, necessary to preserve, without dilution, the purchase rights represented by
Warrants. Upon receipt of such opinion, the Corporation will promptly mail a copy thereof to Warrantholder and will make the adjustments described therein. 
 Section 3.02: Notices of Adjustment. Whenever the number of Warrant Shares is adjusted as herein provided, the Corporation shall prepare and deliver forthwith to the Warrantholder a certificate
signed by its Chief Financial Officer, President or a Vice President, or by the Treasurer or an Assistant Treasurer or the Secretary or an Assistant Secretary, setting forth the adjusted number of shares purchasable upon the exercise of this Warrant
after such adjustment, setting forth a brief statement of the facts requiring such adjustment and setting forth the computation by which adjustment was made. 
 Section 3.03: Form of Warrant After Adjustments. The form of this Warrant need not be changed because of any adjustments in the number or kind of the Warrant Shares, and Warrants theretofore or
thereafter issued may continue to express the same price and number and kind of shares as are stated in this Warrant, as initially issued. 
 Section 3.04: Treatment of Warrantholder. Prior to due presentment for registration of transfer of this Warrant, the Corporation may deem and treat the Warrantholder as the absolute owner of this Warrant (notwithstanding
any notation of ownership or other writing hereon) for all purposes and shall not be affected by any notice to the contrary. 
 ARTICLE IV

 OTHER PROVISIONS RELATING TO RIGHTS OF WARRANTHOLDER 
 Section 4.01: No Rights as Shareholders; Notice to Warrantholders. Nothing contained in this Warrant shall be construed as conferring upon the Warrantholder the right to vote or to receive dividends
or to consent or to receive notice as a shareholder in respect of any meeting of shareholders for the election of directors of the Corporation or of any other matter, or any rights whatsoever as shareholders of the Corporation. The Corporation shall
give notice to the Warrantholder by certified mail if at any time prior to the expiration or exercise in full of the Warrants, any of the following events shall occur: 
 (a) the Corporation shall declare any dividend or distribution with respect to its capital stock; 
 (b) a
dissolution, liquidation or winding up of the Corporation shall be proposed; 
 (c) a capital reorganization or reclassification of the
capital stock of the Corporation; or 
  

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 (d) a Sale of the Corporation. 
 Such giving of notice shall be initiated at least five Business Days prior to the date fixed as a record date or effective date or the date of closing of
the Corporation’s stock transfer books for the determination of the shareholders entitled to such dividend or distribution, or for the determination of the shareholders entitled to vote on such proposed capital reorganization or
reclassification, merger, consolidation, transaction, sale, conveyance, dissolution, liquidation or winding up. Such notice shall specify such record date or the date of closing the stock transfer books, as the case may be. 
 Section 4.02: Lost, Stolen, Mutilated or Destroyed Warrants. If this Warrant is lost, stolen, mutilated or destroyed, the Corporation
may, on such reasonable terms as to indemnity or otherwise as it may in its reasonable discretion impose (which shall, in the case of a mutilated Warrant, include the surrender thereof), issue a new Warrant of like denomination and tenor as, and in
substitution for, this Warrant. 
 ARTICLE V 
 SPLIT-UP, COMBINATION, 
 EXCHANGE AND TRANSFER OF WARRANTS 
 Section 5.01: Split-Up, Combination, Exchange and Transfer of Warrants. Subject to the provisions of Section 5.02 hereof, this
warrant may be split up, combined or exchanged for another Warrant or Warrants containing the same terms to purchase a like aggregate number of Warrant Shares. If the Warrantholder desires to split up, combine or exchange this Warrant, the
Warrantholder shall make such request in writing delivered to the Corporation and shall surrender to the Corporation this Warrant and any other Warrants to be so split-up, combined or exchanged. Upon any such surrender for a split-up, combination or
exchange, the Corporation shall execute and deliver to the person entitled thereto a Warrant or Warrants, as the case may be, as so requested. The Corporation shall not be required to effect any split-up, combination or exchange which will result in
the issuance of a Warrant entitling the Warrantholder to purchase upon exercise a fraction of a share of Common Stock or a fractional Warrant. The Corporation may require such Warrantholder to pay a sum sufficient to cover any tax or governmental
charge that may be imposed in connection with any split-up, combination or exchange of Warrants. 
 Section 5.02:
Transfer. This Warrant and all rights hereunder may not be sold, transferred or otherwise disposed of, without the prior written consent of the Corporation. 
  

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 Section 5.03: Restrictive Legend. Each Warrant Share issued upon exercise of this
Warrant shall bear a legend containing the following words: 
 “THE SHARES EVIDENCED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER
THE SECURITIES ACT OF 1933 OR THE SECURITIES LAWS OF ANY STATE AND MAY NOT BE SOLD OR OTHERWISE DISPOSED OF EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER SUCH ACT AND APPLICABLE STATE SECURITIES LAWS OR AN OPINION OF COUNSEL
REASONABLY ACCEPTABLE TO THE COMPANY TO THE EFFECT THAT THE TRANSACTION PURSUANT TO WHICH SUCH SHARES WILL BE OFFERED FOR SALE OR OTHERWISE DISPOSED OF IS SUBJECT TO AN APPLICABLE EXEMPTION TO THE REGISTRATION REQUIREMENTS OF SUCH ACT OR SUCH
LAWS.” 
 The requirement that the above securities legend be placed upon certificates evidencing shares of Stock shall cease and
terminate upon the earliest of the following events: (i) when such shares are transferred in a public offering registered under the Securities Act, (ii) when such shares are transferred pursuant to Rule 144 under the Securities Act or
(iii) when such shares are transferred in any other transaction if the seller delivers to the Corporation an opinion of its counsel, which counsel and opinion shall be reasonably satisfactory to the Corporation, or a “no-action”
letter from the staff of the Securities and Exchange Commission, in either case to the effect that such legend is no longer necessary in order to protect the Corporation against a violation by it of the Securities Act upon any sale or other
disposition of such shares without registration thereunder. Upon the occurrence of such event, the requirement that the above legend regarding this Agreement be placed upon certificates evidencing shares of Stock shall cease and terminate. Upon the
consummation of any event requiring the removal of a legend hereunder, the Corporation, upon the surrender of certificates containing such legend, shall, at its own expense, deliver to the holder of any such shares as to which the requirement for
such legend shall have terminated, one or more new certificates evidencing such shares not bearing such legend. 
 ARTICLE VI 
 OTHER MATTERS 
 Section 6.01:
Successors and Assigns. The terms and provisions of this Warrant shall bind and inure to the benefit of the Warrantholder and its successors and assigns. 
 Section 6.02: No Inconsistent Agreements. The Corporation will not on or after the date of this Warrant enter into any agreement with respect to its securities which is inconsistent with the rights
granted to the Warrantholder or otherwise conflicts with the provisions hereof. The rights granted to the Warrantholder hereunder do not in any way conflict with and are not inconsistent with the rights granted to holders of the Corporation’s
securities under any other agreements. 
 Section 6.03: Entire Agreement. This Warrant and the Exhibits hereto contain the
entire agreement among the parties with respect to the subject matter hereof and supersede all prior and contemporaneous arrangements or understandings with respect thereto. 
  

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 Section 6.04: Amendments and Waivers. The terms and provisions of this Warrant,
including the provisions of this sentence, may be modified or amended, or any of the provisions hereof waived, temporarily or permanently, pursuant to the written consent of the Corporation and the Warrantholder. 
 Section 6.05: Counterparts. This Warrant may be executed in any number of counterparts, and each such counterpart hereof, when
executed and delivered to the other party, shall be deemed to be an original instrument, but all such counterparts together shall constitute but one agreement. 
 Section 6.06: Governing Law. This Warrant shall be governed by and construed in accordance with the laws of the Commonwealth of Pennsylvania without giving effect to the principles of conflicts of
law. 
 Section 6.07: Notice. Any notice provided for in this Agreement shall be in writing and shall be either personally
delivered or sent by facsimile or reputable overnight courier service (charges prepaid) to the Corporation at the address set forth below and to the Warrantholder at such address as the Corporation maintains on its books and records, or at such
address or to the attention of such other person as the recipient party has specified by prior written notice to the sending party. Notices will be deemed to have been given hereunder when delivered personally or on receipt. 
 The Corporation’s address is: 
 Precision
Therapeutics, Inc. 
 2516 Jane Street 
 Pittsburgh, PA 15203 
 Attention: Chief Executive Officer 
 All such notices, requests, consents and other communications shall be deemed to have been given when received. 
 Section 6.08: Severability. Whenever possible, each provision of this Warrant shall be interpreted in such manner as to be effective
and valid, but if any provision of this Warrant is held to be invalid or unenforceable in any respect, such invalidity or unenforceability shall not render invalid or unenforceable any other provision of this Warrant. 
  

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 IN WITNESS WHEREOF, this Warrant Agreement has been duly executed by the Corporation under its corporate
seal as of the 22nd day of August, 2003. 
  

					
	PRECISION THERAPEUTICS, INC.
		
	By:	 	/s/ Sharon Kim
		 	Name:	 	Sharon Kim
		 	Title:	 	Corporate Secretary
	
	WARRANTHOLDER:
	  
 _____________________

		
	By:	 	 
			
		 	Name: 	 	 
			
		 	Title:	 	 

 Exhibit A to Warrant 
 FORM OF SUBSCRIPTION 
 [To be executed only upon exercise of Warrant] 
 PRECISION THERAPEUTICS, INC. 
 The undersigned registered holder of the within Warrant hereby irrevocably exercises such Warrant for, and purchases thereunder, __________1
shares of Common Stock covered by the within Warrant and requests that the certificates for such shares be issued in the name of, and delivered to, _____________ whose address is ________________. The undersigned herewith makes payment in full of
the Exercise Price therefor (or $________ in the aggregate). 
  

					
	Date: _________, 20__	 		 	 
		 		 	(Signature must conform in all respects to name of holder as specified on the face of Warrant)
			
		 		 	 
		 		 	(Street Address)
			
		 		 	 
		 		 	(City)                
(State)                         (Zip Code)

	 1
	 Insert here the number of shares calculated in accordance with the definition of
Exercise Number (or, in the case of a partial exercise, the portion thereof as to which this Warrant is being exercised). In the case of a partial exercise, a new Warrant or Warrants will be issued and delivered, representing the unexercised portion
of the Warrant, to the holder surrendering the Warrant. 

  

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 Exhibit B to Warrant 
 FORM OF NOTICE OF CONVERSION 
 [To be executed only upon conversion of Warrant] 
 PRECISION THERAPEUTICS, INC. 
 The undersigned hereby irrevocably elects to
exercise the right, represented by this Warrant certificate, to convert Warrants represented hereby into ______ shares of Common Stock in accordance with the terms hereof. 
 The undersigned requests that a certificate for such shares be registered in the name of _____________, whose address is ____________ and that such shares be delivered to __________________ whose address is
_______________. 
 If said number of Warrant Shares is less than all of the shares of Common Stock purchasable hereunder, the undersigned requests that a
new Warrant certificate representing the remaining balance of such shares be registered in the name of _______________, whose address is ___________________, and that such Warrant certificate be delivered to _____________, whose address is
____________. 
  

					
	Date: _________, 20__	 		 	 
		 		 	(Signature must conform in all respects to name of holder as specified on the face of Warrant)
			
		 		 	 
		 		 	(Street Address)
			
		 		 	 
		 		 	(City)                
(State)                         (Zip Code)

  

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 Bridge Warrant 
 The
series of warrants represented by this form are substantially identical in all material respects except as to the details below. Accordingly, pursuant to Instruction 2 to Item 601(b) of Regulation S-K, we have filed the form of warrant herewith.

  

			
	Investor	  	Number
of Exercise
Shares
	 Catz, Alvin J.
	  	2,854
	 Catz, Sheila C.
	  	3,640
	 Colker, James & Janice S. (held as Tenants by the Entireties)
	  	18,414
	 Draper Triangle Ventures, LP
	  	228,138
	 Duffy, Mary Beth
	  	5,704
	 Future Fund, Inc
	  	41,294
	 Glausser, Gary G. and Mary Frances
	  	2,282
	 Glausser, Helen P.
	  	571
	 Glausser, Paul B.
	  	1,141
	 HOWNIM Limited Partnership
	  	8,060
	 Janney Montgomery Scott LLC
	  	5,138
	 Kelley, Melissa A. and Carl J. Brotsker
	  	2,065
	 Kornblith, Nicholas
	  	207
	 Kornblith, Paul L.
	  	2,065
	 Krolikowski, John P.
	  	3,771
	 Lapidus, Stanley N.
	  	9,734
	 McDonald, Robert H. Jr
	  	22,814
	 Mendlowitz, Harold
	  	4,420
	 Miller, Bruce W.
	  	1,371
	 Newlin, William R. (Sheldon & Co FBO William R. Newlin Tax ID #34-6510658)
	  	22,533
	 Parks, Timothy E.
	  	351
	 Patton, G. Richard
	  	877
	 Pennsylvania Growth Fund
	  	7,684
	 Renzi, Ned
	  	1,360
	 Robinson, Stephen G.
	  	10,324
	 Route 88 Development Inc.
	  	41,294
	 Ruzika, Roy T. and Joan R.
	  	1,033
	 Sebastian, Sean D.S.
	  	4,130
	 Stephens—Precision Therapeutics, LLC
	  	456,276
	 Thorne, John R.
	  	10,324
	 Thorne, Richard W.
	  	4,536
	 TVM V Life Science Ventures GmbH & Co. KG
	  	456,276
	 Zlatkus, Lizabeth H.
	  	2,389Warrant to Purchase Common Stock issued to General Electric Capital Corp in 2005

 Exhibit 4.14 
 NEITHER THIS WARRANT NOR THE SECURITIES ISSUABLE UPON EXERCISE OF THIS WARRANT HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. NO SALE OR DISPOSITION MAY BE EFFECTED EXCEPT IN COMPLIANCE WITH RULE 144 UNDER SAID ACT OR
WITHOUT AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO OR AN OPINION OF COUNSEL FOR THE HOLDER, SATISFACTORY TO THE COMPANY, THAT SUCH REGISTRATION IS NOT REQUIRED UNDER THE ACT OR RECEIPT OF A NO-ACTION LETTER FROM THE SECURITIES AND EXCHANGE
COMMISSION. 
 WARRANT TO PURCHASE 26,000 SHARES OF COMMON STOCK 
 February 17, 2005 
 THIS CERTIFIES
THAT, for value received, General Electric Capital Corporation (“Holder”) is entitled to subscribe for and purchase Twenty-Six Thousand (26,000) shares of the fully paid and nonassessable Common Stock (the “Shares” or
the “Stock”) of Precision Therapeutics, Inc., a Delaware corporation (the “Company”), at the Warrant Price (as hereinafter defined), subject to the provisions and upon the terms and conditions hereinafter set forth.

 1. Warrant Price. The Warrant Price shall initially be One and 00/100 dollars ($1.00) per share, subject to adjustment as provided in
Section 7 below. 
 2. Conditions to Exercise. The purchase right represented by this Warrant may be exercised at any time, or from time to time,
in whole or in part during the term commencing on the date hereof and ending at 5:00 P.M. Pacific time on the tenth anniversary of the date of this Warrant. 
 3. Method of Exercise; Payment; Issuance of Shares; Issuance of New Warrant. 
 (a) Cash Exercise. Subject to Section 2 hereof,
the purchase right represented by this Warrant may be exercised by the Holder hereof, in whole or in part, by the surrender of this Warrant (with a duly executed Notice of Exercise in the form attached hereto) at the principal office of the Company
(as set forth in Section 18 below) and by payment to the Company, by check, of an amount equal to the then applicable Warrant Price per share multiplied by the number of shares then being purchased. In the event of any exercise of the rights
represented by this Warrant, certificates for the shares of stock so purchased shall be in the name of, and delivered to, the Holder hereof, or as such Holder may direct (subject to the terms of transfer contained herein and upon payment by such
Holder hereof of any applicable transfer taxes). Such delivery shall be made within 30 days after exercise of the Warrant and at the Company’s expense and, unless this Warrant has been fully exercised or expired, a new Warrant having terms and
conditions substantially identical to this Warrant and representing the portion of the Shares, if any, with respect to which this Warrant shall not have been exercised, shall also be issued to the Holder hereof within 30 days after exercise of the
Warrant. 

 (b) Net Issue Exercise. Holder may also elect to receive shares equal to the value of this Warrant (or of any
portion thereof remaining unexercised) by surrender of this Warrant at the principal office of the Company together with notice of such election, in which event the Company shall issue to Holder the number of shares of the Company’s Common
Stock computed using the following formula: 
  

					
	X	 	=	  	Y (A-B)
		 		  	      A
	Where X = the number of shares of Stock to be issued to Holder.
	Y = the number of shares of Stock purchasable under this Warrant (at the date of such calculation).
	A = the Fair Market Value of one share of the Company’s Common Stock (at the date of such calculation).
	B = Warrant Price (as adjusted to the date of such calculation).

 (c) Fair Market Value. For purposes of this Section 3, Fair Market Value of one share of the
Company’s Stock shall mean: 
 (i) In the event of an exercise in connection with an Initial Public Offering, the per share Fair Market
Value for the Stock shall be the per share offering price (as set forth on the front cover of the final prospectus) at which the underwriters initially sell Common Stock to the public; or 
 (ii) The average of the closing bid and asked prices of Common Stock quoted in the Over-The-Counter Market Summary, the last reported sale price quoted on
the Nasdaq National Market (“NNM”) or on any exchange on which the Common Stock is listed, whichever is applicable, as published in the Western Edition of the Wall Street Journal for the ten (10) trading days prior to the date
of determination of Fair Market Value; or 
 (iii) In the event of an exercise in connection with a merger, acquisition or other
consolidation in which the Company is not the surviving entity, the per share Fair Market Value for the Stock shall be the value to be received per share of Common Stock by all holders of the Common Stock in such transaction as determined by the
Board of Directors; or 
 (iv) In any other instance, the per share Fair Market Value for the Stock shall be as determined in good faith by
the Company’s Board of Directors. 
 In the event of 3(c)(iii) or 3(c)(iv), above, the Company’s Board of Directors shall prepare a
certificate, to be signed by an authorized officer of the Company, setting forth in reasonable detail the basis for and method of determination of the per share Fair Market Value of the Stock. The Board will also certify to the Holder that this per
share Fair Market Value will be applicable to all holders of the Company’s Common Stock. Such certification must be made to Holder prior to the proposed effective date of the merger, consolidation, sale, or other triggering event as defined in
3(c)(iii) or 3(c)(iv). 
 (d) Automatic Exercise. To the extent this Warrant is not previously exercised, it shall be automatically exercised in
accordance with Sections 3(b) and 3(c) hereof (even if not surrendered) immediately before its expiration, involuntary termination or cancellation. Holder will be required to submit the Notice of Exercise form attached hereto to the Company in order
to exercise this Warrant. 
  

 - 2 - 

 4. Representations and Warranties of Holder and the Company 
 (a) Representations and Warranties by Holder. The Holder represents and warrants to the Company with respect to this purchase as follows: 
 (i) The Holder has substantial experience in evaluating and investing in private placement transactions of securities of companies similar to the Company
so that the Holder is capable of evaluating the merits and risks of its investment in the Company and has the capacity to protect its interests. 
 (ii) Except for transfers to a Holder’s affiliates, the Holder is acquiring the Warrant and the Shares of Stock issuable upon exercise of the Warrant (collectively the “Securities”) for investment for its own account and not
with a view to, or for resale in connection with, any distribution thereof. The Holder understands that the Securities have not been registered under the Securities Act of 1933, as amended (the “Act”) by reason of a specific exemption from
the registration provisions of the Act which depends upon, among other things, the bona fide nature of the investment intent as expressed herein. 
 (iii) The Holder acknowledges that the Securities must be held indefinitely unless subsequently registered under the Act or an exemption from such registration is available. The Holder is aware of the provisions of Rule 144 promulgated
under the Act. 
 (iv) The Holder is an “accredited investor” within the meaning of Regulation D promulgated under the Act.

 (v) The Holder has had an opportunity to discuss the Company’s business, management and financial affairs with its management and an
opportunity to review the Company’s facilities. The Holder understands that such discussions, as well as the written information issued by the Company, were intended to describe the aspects of the Company’s business and prospects which the
Company believes to be material but were not necessarily a thorough or exhaustive description. 
 (b) Company hereby represents and warrants to Holder that,
except as set forth in the schedule attached to this Warrant as Exhibit A (the “Disclosure Schedule”), the statements in the following paragraphs of this Section 4(b) are true and correct (a) as of the date hereof
and (b) except where any such representation and warranty relates specifically to an earlier date, as of the date of any exercise of this Warrant. 
 (i) Corporate Organization and Authority. Company (a) is a corporation duly organized, validly existing, and in good standing in its jurisdiction of incorporation, (b) has the corporate power and
authority to own and operate its properties and to carry on its business as now conducted and as proposed to be conducted; and (c) is qualified as a foreign corporation in all jurisdictions where such qualification is required. 
 (ii) Corporate Power . Company has all requisite legal and corporate power and authority to execute, issue and deliver the Warrant,
to issue the Common Stock issuable upon exercise or conversion of the Warrant, and to carry out and perform its obligations under the Warrant and any related agreements. 
 (iii) Authorization; Enforceability. All corporate action on the part of Company, its officers, directors and shareholders
necessary for the authorization, execution, delivery and performance of its obligations under this Warrant and for the authorization, issuance and delivery of the Warrant and Stock issuable upon exercise of the Warrant has been taken and this
Warrant constitutes the legally binding and valid obligation of Company enforceable in accordance with its terms. 
  

 - 3 - 

 (iv) Valid Issuance of Warrant and Common Stock. The Warrant has been validly
issued and is free of restrictions on transfer other than restrictions on transfer set forth herein and under applicable state and federal securities laws. The Common Stock issuable upon conversion of this Warrant, when issued, sold and delivered,
in accordance with the terms of this Warrant for the consideration expressed herein, will be duly and validly issued, fully paid and nonassessable, and will be free of restrictions on transfer other than restrictions on transfer under this Warrant
and under applicable state and federal securities laws. Subject to applicable restrictions on transfer, the issuance and delivery of the Warrant and the Common Stock issuable upon conversion of the Warrant are not subject to any preemptive or other
similar rights or any liens or encumbrances except as specifically set forth in Company’s Certificate of Incorporation or this Warrant. The offer, sale and issuance of the Warrant and Common Stock, as contemplated by this Warrant, are exempt
from the prospectus and registration requirements of applicable United States federal and state security laws, and neither Company nor any authorized agent acting on its behalf has or will take any action hereafter that would cause the loss of such
exemption. 
 (v) No Conflict with Other Instruments. The execution, delivery, and performance of this Warrant will not
result in any violation of, be in conflict with, or constitute a default under, with or without the passage of time or the giving of notice (a) any provision of Company’s Certificate of Incorporation or by-laws; (b) any provision of
any judgment, decree, or order to which Company is a party or by which it is bound or an event which results in the creation of any material lien, charge or encumbrance upon any material assets of Company; (c) any contract, obligation, or
commitment to which Company is a party or by which it is bound; or (d) any statute, rule, or governmental regulation applicable to Company. 
 (vi) Capitalization . Company has reserved 26,000 shares of Common Stock for issuance upon exercise of this Warrant. Except as set forth in Section 4(b) of the Disclosure Schedule, there are no outstanding
warrants, options, conversion privileges, preemptive rights or other rights or agreements to purchase or otherwise acquire or issue any equity securities or convertible Securities of Company, nor has the issuance of any of the aforesaid rights to
acquire securities of Company been authorized. 
 (vii) Governmental Consents. No consent, approval, order or
authorization of, or registration, qualification, designation, declaration or filing with, any federal, state or local governmental authority on the part of Company is required in connection with the offer, sale or issuance of the Warrant (and the
Stock issuable upon the exercise of this Warrant), or the consummation of any other transaction contemplated hereby, except for the following: (a) the filing of a notice on Form D under the Act and b) the compliance with other applicable state
securities laws, which compliance will have occurred within the appropriate time periods therefore. 
  

 - 4 - 

 5 Legends. 
 (a) Each
certificate representing the Securities shall be endorsed with the following legend: 
 THESE SECURITIES HAVE NOT BEEN REGISTERED UNDER THE
SECURITIES ACT OF 1933 AND MAY NOT BE TRANSFERRED UNLESS COVERED BY AN EFFECTIVE REGISTRATION STATEMENT UNDER SAID ACT, A “NO ACTION” LETTER FROM THE SECURITIES AND EXCHANGE COMMISSION WITH RESPECT TO SUCH TRANSFER, A TRANSFER MEETING THE
REQUIREMENTS OF RULE 144 OF THE SECURITIES AND EXCHANGE COMMISSION, OR AN OPINION OF COUNSEL SATISFACTORY TO THE ISSUER TO THE EFFECT THAT ANY SUCH TRANSFER IS EXEMPT FROM SUCH REGISTRATION. 
 The Company need not enter into its stock records a transfer of Securities unless the conditions specified in the foregoing legend are satisfied. The Company may also
instruct its transfer agent not to allow the transfer of any of the Shares unless the conditions specified in the foregoing legend are satisfied. 
 (b)
Removal of Legend and Transfer Restrictions. The legend relating to the Act endorsed on a certificate pursuant to paragraph 5 (a) of this Warrant shall be removed and the Company shall issue a certificate without such legend to the
Holder of the Securities if (i) the Securities are registered under the Act and a prospectus meeting the requirements of Section 10 of the Act is available or (ii) the Holder provides to the Company an opinion of counsel for the
Holder reasonably satisfactory to the Company, a no-action letter or interpretive opinion of the staff of the SEC reasonably satisfactory to the Company, or other evidence reasonably satisfactory to the Company, to the effect that public sale,
transfer or assignment of the Securities may be made without registration and without compliance with any restriction such as Rule 144. 
 6. Condition of
Transfer or Exercise of Warrant. It shall be a condition to any transfer or exercise of this Warrant that at the time of such transfer or exercise, the Holder shall provide the Company with a representation in writing that the Holder or
transferee is acquiring this Warrant and the shares of Stock to be issued upon exercise for investment purposes only and not with a view to any sale or distribution, or will provide the Company with a statement of pertinent facts covering any
proposed distribution. As a further condition to any transfer of this Warrant or any or all of the shares of Stock issuable upon exercise of this Warrant, other than a transfer registered under the Act, the Company may request a legal opinion, in
form and substance satisfactory to the Company and its counsel, reciting the pertinent circumstances surrounding the proposed transfer and stating that such transfer is exempt from the registration and prospectus delivery requirements of the Act.
The Company shall not require Holder to provide an opinion of counsel if the transfer is to an affiliate of Holder. Each certificate evidencing the shares issued upon exercise of the Warrant or upon any transfer of the shares (other than a transfer
registered under the Act or any subsequent transfer of shares so registered) shall, at the Company’s option, if the Shares are not freely saleable under Rule 144(k) under the Act, contain a legend in form and substance satisfactory to the
Company and its counsel, restricting the transfer of the shares to sales or other dispositions exempt from the requirements of the Act. As further condition to each transfer, at the request of the Company, the Holder shall surrender this Warrant to
the Company and the transferee shall receive and accept a Warrant, of like tenor and date, executed by the Company. 
  

 - 5 - 

 7. Adjustment for Certain Events. The number and kind of securities purchasable upon the exercise of this Warrant
and the Warrant Price shall be subject to adjustment from time to time upon the occurrence of certain events, as follows: 
 (a)
Reclassification or Merger. In case of any reclassification or change of securities of the class issuable upon exercise of this Warrant (other than a change in par value, or from par value to no par value, or from no par value to par value,
or as a result of a subdivision or combination), or in case of any merger of the Company with or into another corporation (other than a merger with another corporation in which the Company is the acquiring and the surviving corporation and which
does not result in any reclassification or change of outstanding securities issuable upon exercise of this Warrant), or in case of any sale of all or substantially all of the assets of the Company, the Company, or such successor or purchasing
corporation, as the case may be, shall duly execute and deliver to the Holder a new Warrant (in form and substance satisfactory to the Holder of this Warrant), or the Company shall make appropriate provision without the issuance of a new Warrant, so
that the Holder shall have the right to receive, at a total purchase price not to exceed that payable upon the exercise of the unexercised portion of this Warrant, and in lieu of the shares of Stock theretofore issuable upon exercise of this
Warrant, the kind and amount of shares of stock, other securities, money and property receivable upon such reclassification, change, merger or sale by a Holder of the number of shares of Stock then purchasable under this Warrant, or in the case of
such a merger or sale in which the consideration paid consists all or in part of assets other than securities of the successor or purchasing corporation, at the option of the Holder, the securities of the successor or purchasing corporation having a
value at the time of the transaction equivalent to the value of the Stock purchasable upon exercise of this Warrant at the time of the transaction. Any new Warrant shall provide for adjustments that shall be as nearly equivalent as may be
practicable to the adjustments provided for in this Section 7. If there is any sale of all or substantially all of the assets of the Company and the acquiring entity does not wish to provide Holder with a new Warrant, then the acquiring company
shall promptly pay the Holder the Fair Market Value of the Warrant at the time of the acquisition. The provisions of this subparagraph (a) shall similarly apply to successive reclassifications, changes, mergers and transfers. 
 (b) Subdivision or Combination of Shares. If the Company at any time while this Warrant remains outstanding and unexpired shall subdivide or
combine its outstanding shares of Common Stock, the Warrant Price shall be proportionately decreased and the number of Shares issuable hereunder shall be proportionately increased in the case of a subdivision and the Warrant Price shall be
proportionately increased and the number of Shares issuable hereunder shall be proportionately decreased in the case of a combination. 
 (c)
Stock Dividends and Other Distributions. If the Company at any time while this Warrant is outstanding and unexpired shall (i) pay a dividend with respect to Common Stock payable in Common Stock, then the Warrant Price shall be adjusted,
from and after the date of determination of shareholders entitled to receive such dividend or distribution, to that price determined by multiplying the Warrant Price in effect immediately prior to such date of determination by a fraction
(A) the numerator of which shall be the total number of shares of Common Stock outstanding immediately prior to such dividend or distribution, and (B) the denominator of which shall be the total number of shares of Common Stock outstanding
immediately after such dividend or distribution; or (ii) make any other distribution with respect to Common Stock (except any distribution specifically provided for in Sections 7(a) and 7(b)), then, in each such case, provision shall be made by
the Company such that the Holder of this Warrant shall receive upon exercise of this Warrant a proportionate share of any such dividend or distribution as though it were the Holder of the Common Stock as of the record date fixed for the
determination of the shareholders of the Company entitled to receive such dividend or distribution. 
  

 - 6 - 

 (d) Adjustment of Number of Shares. Upon each adjustment in the Warrant Price, the number of
Shares purchasable hereunder shall be adjusted, to the nearest whole share, to the product obtained by multiplying the number of Shares purchasable immediately prior to such adjustment in the Warrant Price by a fraction, the numerator of which shall
be the Warrant Price immediately prior to such adjustment and the denominator of which shall be the Warrant Price immediately thereafter. 
 8. Notice of
Adjustments. Whenever any Warrant Price or the kind or number of securities issuable under this Warrant shall be adjusted pursuant to Section 7 hereof, the Company shall prepare a certificate signed by an officer of the Company setting forth, in
reasonable detail, the event requiring the adjustment, the amount of the adjustment, the method by which such adjustment was calculated, and the Warrant Price and number or kind of shares issuable upon exercise of the Warrant after giving effect to
such adjustment, and shall cause copies of such certificate to be mailed (by certified or registered mail, return receipt required, postage prepaid) within thirty (30) days of such adjustment to the Holder of this Warrant as set forth in
Section 16 hereof. 
 9. Transferability of Warrant. This Warrant is transferable on the books of the Company at its principal office by the
registered Holder hereof upon surrender of this Warrant properly endorsed, subject to compliance with Section 6 and applicable federal and state securities laws. The Company shall issue and deliver to the transferee a new Warrant representing
the Warrant so transferred. Upon any partial transfer, the Company will issue and deliver to Holder a new Warrant with respect to the Warrant not so transferred. Holder shall not have any right to transfer any portion of this Warrant to any direct
competitor of the Company. 
 10. No Fractional Shares. No fractional share of Common Stock will be issued in connection with any exercise hereunder,
but in lieu of such fractional share the Company shall make a cash payment therefor upon the basis of the Warrant Price then in effect. 
 11. Charges,
Taxes and Expenses. Issuance of certificates for shares of Common Stock upon the exercise of this Warrant shall be made without charge to the Holder for any United States or state of the United States documentary stamp tax or other incidental
expense with respect to the issuance of such certificate, all of which taxes and expenses shall be paid by the Company, and such certificates shall be issued in the name of the Holder. 
 12. No Shareholder Rights Until Exercise. This Warrant does not entitle the Holder hereof to any voting rights or other rights as a shareholder of the Company prior to the exercise hereof. 
 13. Registry of Warrant. The Company shall maintain a registry showing the name and address of the registered Holder of this Warrant. This Warrant may be
surrendered for exchange or exercise, in accordance with its terms, at such office or agency of the Company, and the Company and Holder shall be entitled to rely in all respects, prior to written notice to the contrary, upon such registry.

 14. Loss, Theft, Destruction or Mutilation of Warrant. Upon receipt by the Company of evidence reasonably satisfactory to it of the loss, theft,
destruction or mutilation of this Warrant, and, in the case of loss, theft, or destruction, of indemnity reasonably satisfactory to it, and, if mutilated, upon surrender and cancellation of this Warrant, the Company will execute and deliver a new
Warrant, having terms and conditions substantially identical to this Warrant, in lieu hereof. 
  

 - 7 - 

 15. Miscellaneous. 
 (a) Issue Date. The provisions of this Warrant shall be construed and shall be given effect in all respect as if it had been issued and delivered by the Company on the date hereof. 
 (b) Successors. This Warrant shall be binding upon any successors or assigns of the Company. 
 (c) Governing Law. This Warrant shall be governed by and construed in accordance with the laws of the State of Delaware. 
 (d) Headings. The headings used in this Warrant are used for convenience only and are not to be considered in construing or interpreting this
Warrant. 
 (e) Saturdays, Sundays, Holidays. If the last or appointed day for the taking of any action or the expiration of any right
required or granted herein shall be a Saturday or a Sunday or shall be a legal holiday in the State of Connecticut, then such action may be taken or such right may be exercised on the next succeeding day not a legal holiday. 
 (f) Waiver of Jury Trial. Each of the parties hereto hereby waives to the fullest extent permitted by applicable law, any right it may have to a
trial by jury in respect of any litigation directly or indirectly arising out of, under or in connection with this Warrant or the Shares. 
 (g) Attorney’s Fees. In the event of any dispute between the parties concerning the terms and provisions of this Warrant, the party prevailing, either the Company or the Holder, in such dispute shall be entitled to collect from
the other party all costs incurred in such dispute, including reasonable attorney’s fees. 
 16. No Impairment. The Company will not, by
amendment of its Certificate of Incorporation or any other voluntary action, avoid or seek to avoid the observance or performance of any of the terms of this Warrant, but will at all times in good faith assist in the carrying out of all such terms
and in the taking of all such action as may be necessary or appropriate in order to protect the rights of the Holder hereof against impairment. 
 17.
Addresses. Any notice required or permitted hereunder shall be in writing and shall be mailed by overnight courier, registered or certified mail, return receipt required, and postage prepaid, or otherwise delivered by hand or by messenger,
addressed as set forth below, or at such other address as the Company or the Holder hereof shall have furnished to the other party. 
  

			
	If to the Company:	  	 Precision Therapeutics, Inc.
 2516 Jane Street

 Pittsburgh, PA 15203
 Attn: Mr. Jeffrey
Wahal

		
	If to the Holder:	  	 General Electric Capital Corporation
 83
Wooster Heights Road 5th Floor
 Danbury, CT
06810
 Attn: Credit Manager

  

 - 8 - 

 IN WITNESS WHEREOF, Precision Therapeutics, Inc. has caused this Warrant to be executed by its
Officers thereunto duly authorized. 
 Dated as of February 17, 2005 
  

			
	By:	 	/s/ Sharon Kim
	Name:	 	Sharon Kim
	Title:	 	VP, Bus Dev & Finance

  

 - 9 - 

 NOTICE OF EXERCISE 
 TO: 
 The undersigned Warrant-holder (“Holder”) elects to acquire shares of Stock (the “Common Stock”) of
Precision Therapeutics, Inc., (the “Company”), pursuant to the terms of the Stock Purchase Warrant dated February 17, 2005 (the “Warrant”). 
  

	1.	The Holder exercises its rights under the Warrant as set forth below: 

  

			
	 (        )
	  	The Holder elects to purchase                      shares of Common Stock as
provided in Section 3(a) and tenders herewith a check in the amount of $                 as payment of the purchase price.
		
	 (        )
	  	The Holder elects to convert the purchase rights into shares of Common Stock as provided in Section 3(b) of the Warrant.

  

	2.	The Holder surrenders the Warrant with this Notice of Exercise. 

 The
Holder represents that it is acquiring the aforesaid shares of Common Stock for investment and not with a view to or for resale in connection with distribution and that the Holder has no present intention of distributing or reselling the shares.

 Please issue a certificate representing the shares of the Common Stock in the name of the Holder or in such other name as is specified below: 

Name: 
 Address: 
 Taxpayer I.D.: 
  

			
	 
	(Holder)
		
	By: 	 	 
		
	Title: 	 	 
		
	Date:

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