Document:

EX-10.3

 Exhibit 10.3 

Grant No.: [__] 
 THIS
NONSTATUTORY STOCK OPTION DEED OF AGREEMENT is made on [Date of Grant] 

BETWEEN: 
 (1) PURETECH
HEALTH PLC (a company registered in England under number 9582467) whose registered office is at 5th Floor, 6 St Andrew Street, London EC4A 3AE, United Kingdom (“Company”); and 

(2) [Recipient Name] (“Service Provider” or “you”) 

BACKGROUND 
  

	A.	 This agreement (“Agreement”) is made and the Options hereby granted are granted pursuant to
and subject to the terms of the PureTech Health plc Performance Share Plan (“Plan”). 

  

	B.	 The Service Provider is providing services to the Company (and/or one or more of its Affiliates) at the date of
this Agreement. 

 BY THIS DEED IT IS AGREED
AS FOLLOWS: 
 1. Terminology. Capitalized terms used in this Agreement but which are
not otherwise defined shall have the meanings ascribed thereto in the Glossary at the end of the Agreement or in the Plan. 
 2. Grant
and Exercise of Option. 
 (a) By this Agreement, the Company hereby grants to the Service Provider [# of Shares] stock options
(“Options”), each Option permitting the purchase of one Share, subject to the terms of this Agreement and to the Plan, at an option exercise price (“Exercise Price”) of [_____] pence per Share. 

(b) Exercisability. The Options will vest and become exercisable in accordance with the Exercisability Schedule set forth in the
schedule to this Agreement (the “Exercisability Schedule”), so long as you are in the Service of the Company from the Grant Date through the applicable exercisability dates. None of the Options will become exercisable after your
Service with the Company ceases. 
 (c) Right to Exercise. You may exercise the Options, to the extent vested and exercisable, at any
time on or before the close of the principal market for the Shares on the Expiration Date or the earlier termination of the Options, unless otherwise provided under applicable law or the Plan. In particular, the Options shall not vest and you may
not exercise the Options at any time when any Dealing Restrictions prohibit such vesting or exercise. Notwithstanding the foregoing, if at any time the Administrator determines that the delivery of Shares under the Plan or this Agreement is or may
be unlawful under the laws of any applicable 

  
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jurisdiction, or federal, state or foreign securities laws, the right to exercise the Options or receive Shares pursuant to the Options shall be suspended until the Administrator determines that
such delivery is lawful. If at any time the Administrator determines that the delivery of Shares under the Plan or this Agreement is or may violate the rules of the securities exchange on which the Shares are then listed for trade, the right to
exercise the Options or receive Shares pursuant to the Options shall be suspended until the Administrator determines that such exercise or delivery would not violate such rules. Section 3 below describes certain limitations on exercise of the
Options that apply in the event of your death, Total and Permanent Disability, or termination of Service. Exercise of the Options may also be limited in the event of certain corporate events as provided in the Plan. The Options may be exercised only
in multiples of whole Shares and may not be exercised at any one time as to fewer than one hundred Shares (or such lesser number of Shares as to which the Options are then exercisable). No fractional Shares will be issued under the Options. 

(d) Exercise Procedure. In order to exercise the Options, you must provide the following items to the Secretary of the Company or his
or her delegate before the expiration or termination of the Options: 
  

	 	(i)	 notice, in such manner and form as the Administrator may require from time to time, specifying the number of
Shares to be purchased under the Options; and 

  

	 	(ii)	 full payment of the Exercise Price for the Shares each in accordance with Section 2(e) of this Agreement.

 An exercise will not be effective until the Secretary of the Company or his or her delegate receives all of the foregoing items, and
such exercise otherwise is permitted under and complies with all applicable federal, state and foreign securities laws. 
 (e) Method of
Payment. You may pay the Exercise Price by: 
  

	 	(i)	 delivery of cash, certified or cashier’s check, money order or other cash equivalent acceptable to the
Administrator in its discretion; 

  

	 	(ii)	 any other method approved by the Administrator; or 

 

	 	(iii)	 any combination of the foregoing. 

(f) Issuance of Shares upon Exercise. The Company shall issue to you the Shares underlying the Options you exercise as soon as
reasonably practicable after the valid exercise of the Options, subject to the Company’s receipt of requisite withholding taxes, if any. 

3. Termination of Service. 

(a) Termination of Unexercisable Options. If your Service with the Company ceases for any reason, the Options that are then unvested
and unexercisable will terminate immediately upon such cessation. 

  
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 (b) Exercise Period Following Termination of Service. If your Service with the
Company ceases for any reason other than for Cause, the Options that are then vested and exercisable will terminate upon the earliest of: 

(i) the expiration of 90 days following such cessation, if your Service ceases on account of (1) your termination by the
Company other than for Cause or termination without Cause, or (2) your voluntary termination other than for Total and Permanent Disability or death; 

(ii) the expiration of 6 months following such cessation, if your Service ceases on account of your Total and Permanent
Disability or death or your termination by the Company without Cause; or 
 (iii) the Expiration Date. 

In the event of your death, the exercisable Options may be exercised by your executor, personal representative, or the person(s) to whom the Options are
transferred by will or the laws of descent and distribution. 
 (c) Misconduct. The Options will terminate in their entirety,
regardless of whether the Options are then exercisable, immediately upon cessation of your Service with the Company for Cause or Gross Misconduct, or upon your commission of any of the following acts during the exercise period following your
termination of Service: (i) fraud on or misappropriation of any funds or property of the Company, or (ii) your breach of any provision of any employment, services, non-disclosure, non-competition, non-solicitation, assignment of inventions, or other similar agreement executed by you for the benefit of the Company, as determined by the Administrator,
which determination will be conclusive. 
 (d) Changes in Status. If you cease to be a “common law employee” of the Company
but you continue to provide bona fide services to the Company following such cessation in a different capacity, including without limitation as a director, consultant or independent contractor, or vice versa, then a termination of Service shall not
be deemed to have occurred for purposes of this Section 3 upon such change in capacity. In the event that your Service is with a business, trade or entity that, after the Grant Date, ceases for any reason to be part or an Affiliate of the
Company, your Service will be deemed to have terminated for purposes of this Section 3 upon such cessation if your Service does not continue uninterrupted immediately thereafter with the Company or an Affiliate of the Company. 

4. Nontransferability of Options. These Options are nontransferable otherwise than by will or the laws of descent and distribution and
during your lifetime, the Options may be exercised only by you or, during the period you are under a legal disability, by your guardian or legal representative. Except as provided above, the Options may not be assigned, transferred, pledged,
hypothecated or disposed of in any way (whether by operation of law or otherwise) and shall not be subject to execution, attachment or similar process. Any purported, assignment, transfer, pledge, hypothecation or disposal shall cause the Options to
lapse immediately and as such they will immediately cease to be exercisable. 
 5. Nonqualified Nature of the Options. The Options
are not intended to qualify as incentive stock options within the meaning of Code section 422, and this Agreement shall be so construed. You hereby acknowledge that you shall be solely responsible for all and any taxes, social security contributions
(or equivalent in any other jurisdiction) which may be payable in respect of the grant or exercise of the Option (including any sales or value added taxes) and hereby agree to comply with the provisions of Section 7 of this Agreement with
respect to any tax withholding obligations that arise as a result of such grant or exercise. 

  
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 6. Withholding of Taxes. 

(a) At the time the Options are exercised, in whole or in part, or at any time thereafter as requested by the Company, you hereby authorize
withholding from payroll or any other payment of any kind due to you and otherwise agree to make adequate provision for foreign, federal, state and local taxes required by law to be withheld, if any, which arise in connection with the Options. The
Company may require you to make a cash payment to cover any withholding tax obligation as a condition of exercise of the Options or issuance of share certificates representing Shares. 

(b) The Administrator may, in its sole discretion, permit you to satisfy, in whole or in part, any withholding tax obligation which may arise
in connection with the Options either by electing to have the Company withhold and sell on your behalf from the Shares to be issued upon exercise that number of Shares having a Fair Market Value not in excess of the amount necessary to satisfy the
statutory minimum withholding amount due. 
 7. Adjustments. The Administrator may make various adjustments to your Options,
including adjustments to the number and type of securities subject to the Options and the Exercise Price, in accordance with the terms of the Plan. 

8. Non-Guarantee of Employment or Service Relationship. Nothing in the Plan or this Agreement
will alter your at-will or other employment status or other service relationship with the Company, nor be construed as a contract of employment or service relationship between you and the Company, or as a
contractual right for you to continue in the employ of, or in a service relationship with, the Company for any period of time, or as a limitation of the right of the Company to terminate your Service for the Company at any time with or without Cause
or notice and whether or not such termination results in the failure of any of the Options to become exercisable or any other adverse effect on your interests under the Plan. 

You hereby waive any and all rights to compensation or damages in consequence of the termination of your Service for any reason whatsoever
insofar as those rights arise or may arise from you ceasing to have rights under or to be entitled to exercise the Options or to be entitled to participate in the Plan as a result of such termination. 

9. No Rights as a Stockholder. You shall not have any of the rights of a stockholder with respect to the Shares until such Shares have
been issued to you upon the due exercise of the Options. No adjustment will be made for dividends or distributions or other rights for which the record date is prior to the date such Shares are issued. 

10. The Company’s Rights. The existence of the Options shall not affect in any way the right or power of the Company or its
stockholders to make or authorize any or all adjustments, recapitalizations, reorganizations or other changes in the Company’s capital structure or its business, or any merger or consolidation of the Company, or any issue of bonds, debentures,
preferred or other stocks with preference ahead of or convertible into, or otherwise affecting the Shares or the rights thereof, or the dissolution or liquidation of the Company, or any sale or transfer of all or any part of the Company’s
assets or business, or any other corporate act or proceeding, whether of a similar character or otherwise. 
 11. Entire Agreement.
This Agreement, together with the Plan, contain the entire agreement between you and the Company with respect to the Options. Any oral or written agreements, representations, warranties, written inducements, or other communications made prior to the
execution of this Agreement with respect to the Options shall be void and ineffective for all purposes. 

  
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 12. Amendment. This Agreement may be amended from time to time by the Administrator
in its discretion; provided, however, that this Agreement may not be modified in a manner that would have a materially adverse effect on the Options or Shares as determined in the discretion of the Administrator, except as provided in
the Plan or in a written document signed by you and the Company. 
 13. Conformity with Plan. This Agreement is intended to conform
in all respects with, and is subject to all applicable provisions of, the Plan. Any conflict between the terms of this Agreement and the Plan shall be resolved in accordance with the terms of the Plan. In the event of any ambiguity in this Agreement
or any matters as to which this Agreement is silent, the Plan shall govern. A copy of the Plan is provided to you with this Agreement. 

14. Section 409A. This Agreement and the Options granted hereunder are intended to be exempt from Section 409A of the Code. This
Agreement and the Options shall be administered, interpreted and construed in a manner consistent with this intent. Nothing in the Plan or this Agreement shall be construed as including any feature for the deferral of compensation other than the
deferral of recognition of income until the exercise of the Options. Should any provision of the Plan or this Agreement be found not to comply with, or otherwise be exempt from, the provisions of Section 409A of the Code, it may be modified and
given effect, in the sole discretion of the Administrator and without requiring your consent, in such manner as the Administrator determines to be necessary or appropriate to comply with, or to effectuate an exemption from, Section 409A of the
Code. The foregoing, however, shall not be construed as a guarantee or warranty by the Company of any particular tax effect to you. 
 15.
Electronic Delivery of Documents. By your signing this Agreement, you (i) consent to the electronic delivery of this Agreement, all information with respect to the Plan and the Options, and any reports of the Company provided generally
to the Company’s stockholders; (ii) acknowledge that you may receive from the Company a paper copy of any documents delivered electronically at no cost to you by contacting the Company by telephone or in writing; (iii) further
acknowledge that you may revoke your consent to the electronic delivery of documents at any time by notifying the Company of such revoked consent by telephone, postal service or electronic mail; and (iv) further acknowledge that you understand
that you are not required to consent to electronic delivery of documents. 
 16. No Future Entitlement. By execution of this
Agreement, you acknowledge and agree that: (i) the grant of these Options is a one-time benefit which does not create any contractual or other right to receive future grants of stock options, or
compensation in lieu of stock options, even if stock options have been granted repeatedly in the past; (ii) all determinations with respect to any such future grants, including, but not limited to, the times when stock options shall be granted
or shall become exercisable, the maximum number of Shares subject to each stock option, and the purchase price, will be at the sole discretion of the Administrator; (iii) the value of these Options is an extraordinary item of compensation which
is outside the scope of your employment or services contract, if any; (iv) the value of these Options is not part of normal or expected compensation or salary for any purpose, including, but not limited to, calculating any termination,
severance, resignation, redundancy, end of service payments or similar payments, or bonuses, long-service awards, pension or retirement benefits; (v) the vesting of these Options ceases upon termination of your Services with the Company or
transfer of your Services from the Company, or other cessation of eligibility for any reason, except as may otherwise be explicitly provided in this Agreement; (vi) if the underlying Shares does not increase in value, these Options will have no
value, nor does the Company guarantee any future value; and (vii) no claim or entitlement to compensation or damages arises if these Options do not increase in value and you irrevocably release the Company from any such claim that does arise.

  
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 17. Personal Data. For the purpose of implementing, administering and managing these
Options, you, by execution of this Agreement, consent to the collection, receipt, use, retention and transfer, in electronic or other form, of your personal data by the Company, any Affiliate, trustee or third party service provider or any potential
future purchaser or merger partner of the Company or an Affiliate. You understand that personal data (including but not limited to, name, home address, telephone number, employee/service provider number, employment status, social security number,
tax identification number, date of birth, nationality, job and payroll location, data for tax withholding purposes and shares awarded, cancelled, exercised, vested and unvested) may be transferred to third parties assisting in the implementation,
administration and management of these Options and the Plan and you expressly authorize such transfer as well as the retention, use, and the subsequent transfer of the data by the recipient(s). You understand that these recipients may be located in
your country or elsewhere, and that the recipient’s country may have different data privacy laws and protections than your country. You understand that data will be held only as long as is necessary to implement, administer and manage these
Options. You understand that you may, at any time, request a list with the names and addresses of any potential recipients of the personal data, view data, request additional information about the storage and processing of data, require any
necessary amendments to data or refuse or withdraw the consents herein, in any case without cost, by contacting in writing the Company’s Secretary. You understand, however, that refusing or withdrawing your consent may affect your ability to
accept a stock option. 
 18. Governing Law. The validity, construction and effect of this Agreement, and of any determinations or
decisions made by the Administrator relating to this Agreement, and the rights of any and all persons having or claiming to have any interest under this Agreement, shall be determined exclusively in accordance with the laws of England and the courts
of England shall have exclusive jurisdiction to settle any dispute which may arise out of or in connection with this Agreement or the Plan. Any proceedings suit or action arising out of this Agreement or the Plan shall be brought in such courts.

 19. Resolution of Disputes. Any dispute or disagreement which shall arise under, or as a result of, or pursuant to or relating to,
this Agreement shall be determined by the Administrator in good faith in its absolute and uncontrolled discretion, and any such determination or any other determination by the Administrator under or pursuant to this Agreement and any interpretation
by the Administrator of the terms of this Agreement, will be final, binding and conclusive on all persons affected thereby. You agree that before you may bring any legal action arising under, as a result of, pursuant to or relating to, this
Agreement you will first exhaust your administrative remedies before the Administrator. You further agree that in the event that the Administrator does not resolve any dispute or disagreement arising under, as a result of, pursuant to or relating
to, this Agreement to your satisfaction, no legal action may be commenced or maintained relating to this Agreement more than twenty-four (24) months after the Administrator’s decision. 

20. Counterparts. This deed may be executed in any number of counterparts each of which, when executed by one or more of the parties
hereto, shall constitute and original but all of which shall constitute one and the same instrument 

  
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 21. Headings. The headings in this Agreement are for reference purposes only and
shall not affect the meaning or interpretation of this Agreement. 
 {Glossary begins on next page} 

  
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 GLOSSARY 

(a) “Company” includes PureTech Health plc and its Affiliates, except where the context otherwise requires. 

(b) “Expiration Date” means the last business day prior to the 10th anniversary of the Grant Date. 

(c) “Grant Date” means the date of this Agreement. 

(d) “Service” means your employment or other service relationship with the Company and its Affiliates. Your Service
will be considered to have ceased with the Company and its Affiliates if, immediately after a sale, merger or other corporate transaction, the trade, business or entity with which you are employed or otherwise have a service relationship is not the
Company or its successor or an Affiliate of the Company or its successor. 
 (e) “Total and Permanent Disability”
means the inability to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment which can be expected to result in death or which has lasted or can be expected to last for a continuous period
of not less than twelve months. The Administrator may require such proof of Total and Permanent Disability as the Administrator in its sole discretion deems appropriate and the Administrator’s good faith determination as to whether you are
totally and permanently disabled will be final and binding on all parties concerned. 
 (f) “You”;
“Your”. “You” or “your” means the Service Provider or the Service Provider’s, respectively. Whenever the Agreement refers to “you” under circumstances where the provision should logically be
construed, as determined by the Administrator, to apply to your estate, personal representative, or beneficiary to whom the Options may be transferred by will or by the laws of descent and distribution, the word “you” shall be deemed to
include such person. 

  
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 SCHEDULE 

EXERCISABILITY SCHEDULE 
 Subject to the
terms and conditions described in the Agreement and the Plan, the Options vest and become exercisable as follows: 
  

	 	(a)	 [25]% of the Options (i.e. to acquire a total of [____] Shares, the “Initial Shares”) vest and
become exercisable on [______] (the “Initial Vesting Date”), and 

  

	 	(b)	 [75]% of the Options (i.e. to acquire a total of [____] Shares) vest and become exercisable in 6 equal
semi-annual installments (the Shares vesting in each such Semi-Annual Period, the “Semi-Annual Shares”) with the first such installment vesting on the 6-month anniversary of the Initial
Vesting Date and an additional installment each 6-month anniversary thereafter through the third anniversary of the Initial Vesting Date (each such semi-annual vesting period, a “Semi-Annual
Period”). 

 The extent to which the Options are exercisable as of a particular date is rounded down to the nearest whole Share.
However, exercisability is rounded up to 100% on the third anniversary of the Initial Vesting Date. 

  
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	Executed as a deed, but not delivered until the first date specified on page 1, by PURETECH HEALTH PLC by a director in the presence of a witness:	 	)	  		 	
	 	)	  		 	
	 	)	  		 	
	 	)	  	Signature	 	
 

							
				
		 		  	Name (block capitals)	  	 Stephen Muniz

		 		  		  	Director

							
			
	Witness signature	 	  
	  	
			
	Witness name	 	  
	  	
	(block capitals)	 		  	

							
			
	Witness address	 	 501 Boylston Street
	  	

							
			
		 	 Suite 6102
	  	

							
			
		 	Boston, MA 02116	  	

  

							
	Signed as a deed, but not delivered until the first date specified on page 1, by [Recipient Name] in the presence of:	  	 
 
 

	)
 )

)
 )
	 
  
  

 
	  	Signature
                                         
                                   

					
			
	Witness signature	  	 	  	

					
			
	Witness name	  	 	  	
			
	(block capitals)	  		  	

					
			
	Witness address	  	 	  	
			
		  	 	  	
			
		  	 	  	

 [PureTech Health – Signature Page to Nonstatutory Stock Option Deed of Agreement]EX-10.4

 Exhibit 10.4 

PURETECH HEALTH PLC 

PERFORMANCE SHARE PLAN 

RESTRICTED SHARE UNITS NOTICE 

Name of Grantee:
                                         
            
 This Notice evidences the Award for a target number
(“Target RSUs”) of restricted share units (each, an “RSU,” and collectively, the “RSUs”) of PureTech Health plc, a public limited company incorporated under English law (the
“Company”), granted to you pursuant to the PureTech Health plc Performance Share Plan (the “Plan”) and conditioned upon your agreement to the terms of the attached Restricted Share Units Agreement
(the “Agreement”). This Notice constitutes part of and is subject to the terms and provisions of the Agreement and the Plan, which are incorporated by reference herein. Each RSU is a bookkeeping entry representing the
equivalent in value of one share of the Company’s ordinary share capital (each, a “Share”). The number of RSUs that you actually earn for the Performance Period will be determined by the level of satisfaction of the
Performance Conditions in accordance with Exhibit A to the Agreement. 
 Grant Date: ____, 20__ 

Performance Period: The period starting on [INSERT], and ending on [INSERT]. 

Target RSUs: [INSERT] 
  

					
	   
	 		 	   

	PureTech Health plc	 		 	Date
	 	 	 	 	 

 I acknowledge that I have read the Agreement and the Plan. I agree to be bound by all of the provisions set
forth in those documents. I also consent to electronic delivery of all notices or other information with respect to the RSUs or the Company. 
  

					
	   
	 		 	   

	Signature of Grantee	 		 	Date

 RESTRICTED SHARE UNITS
AGREEMENT 
 UNDER THE 

PURETECH HEALTH PLC PERFORMANCE SHARE
PLAN 
  

			
	 THIS DEED IS MADE ON
	  	[INSERT]

 BY PURETECH HEALTH PLC (Company number _________________) whose registered office is at _____________________). 

1. Terminology. Unless otherwise provided in this Agreement, capitalized terms used herein are defined in the Glossary at the end of
this Agreement or in the Plan. 
 2. Restricted Share Units. 

(a) Performance Conditions/Determination. The number of RSUs you earn for the Performance Period will be determined by the
Administrator after the end of the Performance Period based on the level of satisfaction of the Performance Conditions in accordance with Exhibit A attached hereto. All determinations of whether Performance Conditions have been
satisfied and the number of RSUs you earn shall be made by the Administrator in its sole discretion. Following completion of the Performance Period, the Administrator will review and certify in writing whether, and to what extent, the Performance
Conditions for the Performance Period have been satisfied and the number of RSUs that you earned, subject to compliance with the remaining terms of this Agreement. Such certification shall be final, conclusive and binding on you and on all other
persons, to the maximum extent permitted by law. 
 (b) Vesting. All of the RSUs are nonvested and forfeitable as of the Grant Date.
Except as otherwise provided herein or in the Plan, the RSUs you earn pursuant to Section 2(a) will Vest and become nonforfeitable on the date in [INSERT] that the Administrator certifies the satisfaction of the Performance Conditions in
accordance with Section 2(a), or if on that date a Dealing Restriction applies, the first date on which it ceases to apply (the “Vesting Date”), so long as you are in continuous Service from the Grant Date through such
Vesting Date. The number of RSUs that Vest and become payable under this Agreement shall be determined by the Administrator based on the level of satisfaction of the Performance Conditions set forth in Exhibit A. Vested RSUs shall be
rounded to the nearest whole RSU. Failure to achieve at least the minimum performance target shall result in the forfeiture of all RSUs. 

(c) Termination of Service. Except as otherwise determined by the Administrator, if your continuous Service terminates for any reason
other than your death, Disability, or termination by the Company without Cause, at any time before the Vesting Date, your unvested RSUs shall be automatically forfeited upon such termination of continuous Service and neither the Company nor any
Affiliate shall have any further obligations to you under this Agreement. 
 If your continuous Service terminates during the Performance
Period as a result of your death, Disability, or termination by the Company without Cause (or, subject to the exercise of such discretion being in compliance with Section 409A of the Code, any other reason which the Administrator in its
discretion determines), this Award will remain eligible to Vest on the Vesting Date. However, the number of Shares in respect of which this Award may Vest shall be determined as follows: (i) the Administrator shall determine the extent to which
any Performance Condition applicable to the Award has been satisfied at the time of Vesting; and (ii) the resulting number of Shares so calculated shall then be reduced on a prorata basis based on the number of days from the beginning of the
Performance Period until Cessation prorata to the original Performance Period, and the resulting figure, rounded up to the nearest whole number of Shares shall be the number of Shares which Vest, provided that the Administrator may in its discretion
determine that exceptional circumstances exist which justify Vesting to a greater extent than the prorating referred to in this Section would allow. 

 (d) Effect of a Specified Event. If a Specified Event occurs during the Performance
Period and you remain in continuous Service through the date of the Specified Event or your Service terminates before the Specified Event as a result of your death, Disability, or termination by the Company without Cause (or, subject to the exercise
of such discretion being in compliance with Section 409A of the Code, any other reason which the Administrator in its discretion determines), you may Vest on the date of the Specified Event in a pro rata portion of the RSUs. The number of
Shares in respect of which this Award may Vest shall be determined as follows: (i) the Administrator shall determine the extent to which, in its reasonable opinion, the Performance Condition applicable to the Award has been satisfied at the
time of the Specified Event and shall calculate the number of Shares in respect of which the Award would be capable of Vesting accordingly; and (ii) unless the Administrator determines not to apply such prorating and to allow Vesting to a
greater extent, the resulting number of Shares so calculated shall then be reduced on a prorata basis based on the number of days from the beginning of the Performance Period applicable to that Award until the earlier of your Cessation or date of
the Specified Event prorata to the Performance Period and the resulting figure, rounded up to the nearest whole number of Shares shall be the number of Shares in respect of which the Award shall Vest. To the extent that the RSUs do not vest in
accordance with this Agreement on a Specified Event, they shall lapse on the occurrence of the Specified Event. 
 (e) Manner of RSU
Settlement. You are required to make a payment of £0.01 per Share by the scheduled settlement date as a condition of settlement of the RSUs. If permitted by the Administrator, you may satisfy such payment by giving an undertaking to pay
such amount and netting and discharging such undertaking against the subsequent proceeds of sale of the Shares delivered in respect of the RSUs that Vest, provided that any such sale shall take place within 14 days following the Vesting of the RSUs
(or such earlier or later date as the Administrator may agree with you). The Company will issue to you, in settlement of your RSUs and subject to satisfaction of tax withholding and the foregoing payment, the number of whole Shares that equals the
number of whole RSUs that become Vested, and such Vested RSUs will terminate and cease to be outstanding upon such issuance of the Shares. Upon issuance of such Shares, the Company will determine the form of delivery (e.g., a stock certificate or
electronic entry evidencing such Shares) and may deliver such Shares on your behalf electronically to the Company’s designated stock plan administrator or such other broker-dealer as the Company may choose at its sole discretion, within reason.

 (f) Timing of RSU Settlement. Your vested RSUs will be settled by the Company, via the issuance of Shares as described herein, on
the earlier of the Vesting Date or Specified Event, or within thirty (30) days thereafter. 
 (g) Dividend Equivalents. Dividend
Equivalents will be paid with respect to vested RSUs. 
 3. Restrictions on Transfer. Neither this Agreement nor any RSU may be
assigned, transferred, pledged, hypothecated or disposed of in any way, whether by operation of law or otherwise, and no right hereunder may be subject to execution, attachment or similar process. All rights with respect to this Agreement shall be
exercisable during your lifetime only by you or your guardian or legal representative. Any purported transfer, assignment, pledge, hypothecation or other disposal shall cause your RSUs to be forfeited and lapse immediately. 

4. Tax Withholding. You agree that you will indemnify the Company and each Affiliate in respect of, and shall be liable to pay to the
Company or the Affiliate, or otherwise make provision satisfactory to the Administrator for payment of, any taxes (including social security or similar contributions) which the Company or any Affiliate is required to withhold and/or account for to
any taxation authority in respect of the RSUs and such payment or provision shall be made no later than the date of the event creating such tax liability. Without prejudice to the generality of the foregoing, the Company or its Affiliate may, to the
extent permitted by law: (i) deduct an amount equal to any such tax liabilities from any payment of any kind otherwise due to you; (ii) withhold and sell such number of Shares to which you 

  
 2 

 
would otherwise become entitled on Vesting or payment as will provide the Company with an amount (after-tax) equal to the amount of such tax and social
security contributions for which it or any Affiliate is obliged to withhold or account; (iii) withhold Shares otherwise issued or issuable to you on Vesting or payment with a Fair Market Value equal to the amount of such tax liabilities; and/or
(iv) if the Shares are then listed for trading on a public market, permit you to enter into a “same day sale” commitment with a broker whereby the grantee irrevocably elects to sell a portion of the Shares to be delivered under this
Agreement to satisfy such tax liabilities and whereby the broker irrevocably commits to forward the proceeds necessary to satisfy such tax liabilities directly to the Company. In the event that payment to the Company or its Affiliate of such tax
liabilities is made in Shares, such Shares shall be valued at Fair Market Value on the applicable date for such purposes. For the avoidance of doubt, the Administrator may specify (to the extent permitted by law) that the social security
contributions which you are liable to pay shall include employer contributions as well as employee contributions. 
 5. Adjustments for
Specified Events and Other Events; Adjustment of Performance Goals. Sections 9 and 10(c) of the Plan describe adjustments that may be made to RSUs as a result of corporate transactions and the treatment of RSUs in corporate transactions. 

6. Non-Guarantee of Employment or Service Relationship. Nothing in the Plan or this
Agreement shall alter your at-will or other employment status or other service relationship with the Company, nor be construed as a contract of employment or service relationship between the Company and you,
or as a contractual right of you to continue in the employ of, or in a service relationship with, the Company for any period of time, or as a limitation of the right of the Company to discharge you at any time with or without cause or notice and
whether or not such discharge results in the forfeiture of any nonvested and forfeitable RSUs or any other adverse effect on your interests under the Plan. You hereby waive any and all rights to compensation or damages in consequence of the
termination of your office or employment for any reason whatsoever insofar as those rights arise or may arise from ceasing to have rights under this Award as a result of such termination. 

7. Recovery. Notwithstanding anything to the contrary in this Agreement, all RSUs and Shares issued in settlement of RSUs shall be
subject to the recovery and withholding provisions in Section 7(f) of the Plan which are incorporated herein by reference. 
 8.
Rights as Shareholder. You shall not have any of the rights of a stockholder with respect to any Shares that may be issued in settlement of the RSUs until such Shares have been issued to you. 

9. The Company’s Rights. This Agreement shall not affect in any way the right or power of the Company or its stockholders to make
or authorize any or all adjustments, recapitalizations, reorganizations, or other changes in the Company’s capital structure or its business, or any merger or consolidation of the Company, or any issue of bonds, debentures, preferred or other
stocks with preference ahead of or convertible into, or otherwise affecting the Shares or the rights thereof, or the dissolution or liquidation of the Company, or any sale or transfer of all or any part of the Company’s assets or business, or
any other corporate act or proceeding, whether of a similar character or otherwise. 
 10. Restrictions on Issuance of Shares. The
issuance of Shares upon settlement of the RSUs shall be subject to and in compliance with all applicable requirements of federal, state, or foreign law with respect to such securities. No Shares may be issued hereunder if the issuance of such Shares
would constitute a violation of any applicable federal, state, or foreign securities laws or other law or regulations or the requirements of any stock exchange or market system upon which the Shares may then be listed. The inability of the Company
to obtain from any regulatory body having jurisdiction the authority, if any, deemed by the Company’s legal counsel to be necessary to the lawful issuance of any Shares subject to the RSUs shall relieve the Company of any liability in respect
of the failure to issue such Shares as to which such requisite authority shall not have been obtained. As a condition to the settlement of the RSUs, the Company may require you to satisfy any qualifications that may be necessary or appropriate, to
evidence compliance with any applicable law or regulation, and to make any representation or warranty with respect thereto as may be requested by the Company. 

  
 3 

 11. Notices. All notices and other communications made or given pursuant to this
Agreement shall be given in writing and shall be deemed effectively given upon receipt or, in the case of notices delivered by the Company to you, five (5) days after deposit in the United States mail, postage prepaid, addressed to you at the
last address you provided to the Company, or in the case of notices delivered to the Company by you, addressed to the Company for the attention of its Secretary at its principal executive office or, in either case, if the receiving party consents in
advance, transmitted and received via telecopy or via such other electronic transmission mechanism as may be available to the parties. Notwithstanding the foregoing, the Company may, in its sole discretion, decide to deliver any documents related to
participation in the Plan and this award by electronic means or to request your consent to participate in the Plan or accept this award by electronic means. You hereby consent to receive such documents by electronic delivery and, if requested, to
agree to participate in the Plan through an on-line or electronic system established and maintained by the Company or another third party designated by the Company. 

12. Entire Agreement. This Agreement, together with the Notice and the Plan, contain the entire agreement between the parties with
respect to the award granted hereunder. Any oral or written agreements, representations, warranties, written inducements, or other communications made prior to the execution of this Agreement with respect to the terms hereof shall be void and
ineffective for all purposes. 
 13. Amendment. Subject to the Plan, this Agreement may be amended from time to time by the Company
in its discretion; provided, however, that this Agreement may not be modified in a manner that would have a materially adverse effect on you as determined in the discretion of the Administrator, except as provided in the Plan or in a
written document signed by each of the parties hereto. 
 14. Section 409A. This Agreement and the RSUs are intended either to be
exempt from Section 409A of the Code under the “short-term deferral rule” exemption or comply with Section 409A of the Code. The preceding provision shall not be construed as a guarantee by the Company of any particular tax
effect of this Agreement and in no event shall the Company be liable for any portion of any taxes, penalties, interest or other expenses that may be incurred by you on account of non-compliance with
Section 409A of the Code. 
 15. No Obligation to Minimize Taxes. The Company has no duty or obligation to minimize the tax
consequences to you of this award and shall not be liable to you for any adverse tax consequences to you arising in connection with this award. You are hereby advised to consult with your own personal tax, financial and/or legal advisors regarding
the tax consequences of this award and by signing the Notice, you have agreed that you have done so or knowingly and voluntarily declined to do so. 

16. Conformity with Plan. This Agreement is intended to conform in all respects with, and is subject to all applicable provisions of,
the Plan. Inconsistencies between this Agreement and the Plan shall be resolved in accordance with the terms of the Plan. In the event of any ambiguity in this Agreement or any matters as to which this Agreement is silent, the Plan shall govern.

 17. No Funding. This Agreement constitutes an unfunded and unsecured promise by the Company to issue Shares in the future in
accordance with its terms. You have the status of a general unsecured creditor of the Company as a result of receiving this award. 
 18.
Effect on Other Employee Benefit Plans. The value of the awards under this Agreement shall not be included as compensation, earnings, salaries, or other similar terms used when calculating your benefits under any employee benefit plan
sponsored by the Company or any Affiliate, except as such plan otherwise expressly provides. The Company expressly reserves its right to amend, modify, or terminate any of the Company’s or any Affiliate’s employee benefit plans. 

  
 4 

 19. Governing Law. The validity, construction and effect of the Plan, this Agreement,
and of any rules, regulations, determinations or decisions made by the Administrator relating to the Plan or this Agreement, and the rights of any and all persons having or claiming to have any interest therein or thereunder, shall be determined
exclusively in accordance with the laws of England and the courts of England shall have exclusive jurisdiction to settle any dispute which may arise out of or in connection with the Plan. Any proceedings suit or action arising out of the Plan shall
be brought in such courts. 
 20. Resolution of Disputes. Any dispute or disagreement which shall arise under, or as a result of, or
pursuant to or relating to, this Agreement shall be determined by the Administrator in good faith in its absolute and uncontrolled discretion, and any such determination or any other determination by the Administrator under or pursuant to this
Agreement and any interpretation by the Administrator of the terms of this Agreement, will be final, binding and conclusive on all persons affected thereby. You agree that before you may bring any legal action arising under, as a result of, pursuant
to or relating to, this Agreement you will first exhaust your administrative remedies before the Administrator. You further agree that in the event that the Administrator does not resolve any dispute or disagreement arising under, as a result of,
pursuant to or relating to, this Agreement to your satisfaction, no legal action may be commenced or maintained relating to this Agreement more than twenty-four (24) months after the Administrator’s decision. 

21. Headings. The headings in this Agreement are for reference purposes only and shall not affect the meaning or interpretation of this
Agreement. 
 22. Electronic Delivery of Documents. By your signing the Notice, you (i) consent to the electronic delivery of
this Agreement, all information with respect to the Plan and the RSUs, and any reports of the Company provided generally to the Company’s stockholders; (ii) acknowledge that you may receive from the Company a paper copy of any documents
delivered electronically at no cost to you by contacting the Company by telephone or in writing; (iii) further acknowledge that you may revoke your consent to the electronic delivery of documents at any time by notifying the Company of such
revoked consent by telephone, postal service or electronic mail; and (iv) further acknowledge that you understand that you are not required to consent to electronic delivery of documents. 

23. Data Privacy. The Company may pass personal information about you (including, but without prejudice to the generality of the
foregoing, your name, address, age and salary details) to third parties for the purpose of administration or for complying with its legal obligations. 

24. Rights of Third Parties. A person who is not a party to this Agreement shall have no right under the Contracts (Rights of Third
Parties) Act 1999 to enforce any term of this agreement save that any person which is obliged to account for any tax or social security contributions shall be entitled to enforce Section 4. This clause does not affect any right or remedy of any
person which exists or is available otherwise than pursuant to that Act. 
 25. Counterparts. This Agreement may be executed in any
number of counterparts each of which, when executed by one or more of the parties hereto, shall constitute an original but all of which shall constitute one and the same instrument. 

{Glossary begins on next page} 

  
 5 

 GLOSSARY 

(a) “Agreement” means this document, as amended from time to time, together with the Plan which is incorporated herein
by reference. 
 (b) “Code” means the Internal Revenue Code of 1986, as amended, and the Treasury regulations and
other guidance promulgated thereunder. 
 (c) “Company” means PureTech Health plc and its Affiliates, except where
the context otherwise requires. 
 (d) “Disability” means that you are unable to engage in any substantial gainful
activity by reason of any medically determinable physical or mental impairment that can be expected to result in death or can be expected to last for a continuous period of not less than 12 months 

(e) “Grant Date” means the effective date of a grant of RSUs made to you as set forth in the Notice. 

(f) “Notice” means the statement, letter or other written notification provided to you by the Company setting forth
the terms of a grant of RSUs made to you. 
 (g) “Service” means your service as an employee, consultant, director,
advisor, non-executive director or other service relationship with the Company and its Affiliates. Your Service will be considered to have ceased with the Company and/or its Affiliates if, immediately after a
sale, merger, or other corporate transaction, the trade, business, or entity with which you are employed or otherwise have a service relationship is not PureTech Health plc or its successor or an Affiliate of PureTech Health plc or its successor.
The Company reserves the right, in its sole discretion, to determine when your Service has terminated, including in the event of any leave of absence or part-time Service. 

(h) “Specified Event” shall have the meaning provided in the Plan, but limited to an event that would also be a
“change in control event” under Section 409A of the Code. 
 (i) “You” or
“Your” means the recipient of the RSUs as reflected on the applicable Notice. Whenever the word “you” or “your” is used in any provision of this Agreement under circumstances where the provision should
logically be construed, as determined by the Administrator, to apply to the estate, personal representative, or beneficiary to whom the RSUs may be transferred by will or by the laws of descent and distribution, the words “you” and
“your” shall be deemed to include such person. 

  
 6 

							
	Executed as a deed, but not delivered until the first date specified on page 1, by PURETECH HEALTH PLC by a director in the presence of a witness:	 	)	  		 	
	 	)	  		 	
	 	)	  		 	
	 	)	  	Signature	 	
 

							
				
		 		  	Name (block capitals)	  	  

		 		  		  	Director

							
			
	Witness signature	 	  
	  	
			
	Witness name	 	  
	  	
			
	(block capitals)	 		  	

							
			
	Witness address	 	 	  	

							
			
		 	 	  	

							
			
		 	 	  	

  

							
	 Signed as a deed, but not delivered until the

first date specified on page 1, by

◆                         in the
presence of:
	  	 
 
 
	)
 )

)
	 
  
  
	  	Signature
                                         
                                   

					
			
	Witness signature	  	 	  	

					
			
	Witness name	  	 	  	
			
	(block capitals)	  		  	

					
			
	Witness address	  	 	  	
			
		  	 	  	
			
		  	 	  	

 EXHIBIT A 

PURETECH HEALTH PLC 

PERFORMANCE CONDITIONS APPLYING TO THE RESTRICTED SHARE UNITS (“RSUs”) GRANTED UNDER THE PURETECH HEALTH PLC
PERFORMANCE SHARE PLAN (“PSP”) ON [INSERT] 
  

	1	 INTRODUCTION 

This Exhibit A sets out the Performance Conditions for the RSUs granted under the PSP on [INSERT]. The Performance Period for each metric will
commence on [INSERT] and end on [INSERT]. 
 The RSUs will be subject to the following performance measures: 

 

					
	 	  	Weighting	 
	 Growth in Total Shareholder Return (“TSR”)
	  	 	50	% 
	 Relative TSR against:
	  			
	 •  FTSE 250 Index (excluding Investment Trusts)
	  	 	12.5	% 
	 •  MSCI Europe Health Care Index
	  	 	12.5	% 
	 Strategic Objectives
	  	 	25	% 

 The Administrator will determine the extent to which the Performance Conditions have been satisfied as soon as
practicable following the end of the Performance Period and determine the extent to which the RSUs shall Vest. The Administrator’s determination of whether the Performance Conditions have been satisfied shall be final and binding on you. 

Capitalized terms used in this Exhibit A will have the same meaning as in Agreement the rules of the PSP, unless otherwise stated. 

 

	2	 THE TSR PERFORMANCE CONDITION (50% OF THE TARGET RSUs) 

TSR is calculated as the Company’s average Return Index over each trading day during the three month period Performance described below.
The Return Index will be calculated by reference to ‘total-return’ data supplied by Bloomberg or Datastream, or such other data source, as determined by the Administrator. 

The growth in TSR over the Performance Period will be calculated as a percentage per annum as follows: 

[R2 ÷ R1 ] (1/3) - 1 

Where: 

	 	•	 	 R1 = the Company’s average Return Index over each trading day during the three month period ending on
the day before the start of the Performance Period; and 

  

	 	•	 	 R2 = the Company’s average Return Index over each trading day during the three month period ending on
the last day of the Performance Period. 

 The extent to which the TSR Performance Condition has been satisfied and the
Target RSUs subject to this Performance Condition will Vest will be determined as follows: 
  

			
	 TSR growth
	  	 Extent to which the TSR Performance Condition has been
satisfied

	 15% or more per annum
	  	100%
	 Between 7% and 15% per annum
	  	On a straight-line basis between 25% and 100%
	 7% per annum
	  	25%
	 Less than 7% per annum
	  	0%

  

	3	 THE RELATIVE TSR CONDITION (25% OF THE TARGET RSUs) 

Relative TSR will be measured by comparing the TSR performance of the Company against the TSR performance of the constituent companies in the
FTSE 250 Index (excluding Investment Trusts) and the MSCI Europe Health Care Index as follows: 
  

	 	•	 	 in respect of 12.5% of the Target RSUs, by reference to the constituents of the FTSE 250 Index (excluding
Investment Trusts) on the first day of the performance period; and 

  

	 	•	 	 in respect of 12.5% of the Target RSUs by reference to the constituents of the MSCI Europe Health Care Index on
the first day of the performance period 

 For the purposes of each of these relative TSR conditions, TSR for the Company and each of the
companies in the relevant index shall be calculated over the Performance Period as follows (unless the Administrator determines another method of calculation should be used) using a common currency basis (GBP): 

R2 - R1 
 R1 

Where: 
  

	 	•	 	 R1 is the relevant company’s average Return Index over each trading day during the three month period ending
on the day before the start of the Performance Period; 

  

	 	•	 	 R2 is the relevant company’s average Return Index over each trading day during the three month period ending
on the last day of the Performance Period; 

  

	 	•	 	 The Return Index will be calculated by reference to ‘total-return’ data supplied by Bloomberg or
Datastream, or such other data source, as determined by the Administrator. 

  
 9 

 The extent to which each relative TSR condition has been satisfied against each Index will be determined as
follows: 
  

			
	 Company’s TSR performance over the Performance
Period
	  	 Extent to which the relative TSR condition has been
satisfied

	 Company’s TSR performance ranking in the relevant index is upper quartile
	  	100%
	 Company’s TSR performance in the relevant index is between the median of the index and upper
quartile
	  	On a straight line basis between 25% and 100%
	 Company’s TSR performance matches the median TSR performance of the index
	  	25%
	 Company’s TSR performance is below the median TSR performance of the index
	  	0%

 The Administrator shall be entitled, in its absolute discretion to make any such adjustments as it thinks fit (whether
prospective or retrospective) to the methodology or the companies in the relevant index to take account of de-listings, mergers, acquisitions or other such events. 

 

	4	 STRATEGIC OBJECTIVES PERFORMANCE CONDITION (25 % OF THE TARGET RSUs) 

Strategic objectives represent a maximum of 25% of the Target RSUs opportunity. 

Strategic objectives are determined annually under the Company’s Annual Bonus Plan and the same target strategic objectives determined for
a financial period of the Company under the Annual Bonus Plan shall apply to each relevant period in the Performance Period. 
 Results will
be averaged over the Performance Period (with each period representing 1/3rd of the total) and shall be expressed as a percentage (“Performance Percentage”). 

The extent to which the Strategic Objectives Performance Condition has been satisfied and the Target RSUs subject to this Performance Condition
will Vest will be determined as follows: 
  

			
	 Performance Percentage
	  	 Extent to which the Target Strategic Objectives Performance
Condition
has been satisfied

	 100%
	  	100%
	 Between 25% and 100%
	  	On a straight-line basis between 25% and 100%
	 25%
	  	25%
	 Less than 25%
	  	0%

  
 10 

	5	 EARLY TESTING OF THE PERFORMANCE CONDITION 

Where under the rules of the PSP or this Agreement, the Performance Condition is required to be tested prior to the end of the Performance
Period, the Remuneration Administrator shall determine the appropriate basis for the calculation. 
  

	6	 ADJUSTMENTS 

In determining the extent to which the Performance Condition is met, the Remuneration Administrator may: 

 

	 	•	 	 adjust the Performance Condition in exceptional circumstances, for example significant acquisitions/disposal or a
significant change in business strategy; and/or 

  

	 	•	 	 make such adjustments to the calculations as it deems necessary in order to ensure that the targets suitably
measure performance in a manner which is consistent with the objectives of the Performance Condition; and/or 

  

	 	•	 	 make an appropriate adjustment to the calculation in the event of any variation of capital of the Company or a
demerger, delisting, special dividend, rights issue or other event which may, in the Board’s opinion, affect the current or future value of Shares; and/or 

 

	 	•	 	 make an appropriate adjustment to the calculation to take into account any changes in accounting standards or
practice 

 Provided that in all cases the amended Performance Condition will represent a fairer measure of performance and
will not be materially more difficult nor materially easier to satisfy than the original Performance Condition. 
  

	7	 RECOVERY OF VESTING AWARDS 

In accordance with the rules of the Plan, Vesting is subject to Section 7 

  
 11

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