Document:

EX-10.15

 Exhibit 10.15 

2005 EQUITY INCENTIVE PLAN 

OF 
 AVANIR
PHARMACEUTICALS, INC. 
 1. Purpose of this Plan. 

The purpose of this 2005 Equity Incentive Plan is to retain and motivate executives, employees and directors while at the same time aligning
their interests with those of the Company’s stockholders. 
 2. Definitions and Rules of Interpretation. 

2.1. Definitions. 
 This
Plan uses the following defined terms: 
 (a) “Administrator” means the Board or the Committee, or any
officer or employee of the Company to whom the Board or the Committee delegates authority to administer this Plan, but only to the extent of such delegation of authority. 

(b) “Affiliate” means a “parent” or “subsidiary” (as each is defined in Section 424 of the
Code) of the Company and any other entity that the Board or Committee designates as an “Affiliate” for purposes of this Plan. 

(c) “Applicable Law” means any and all laws of whatever jurisdiction, within or without the United States, and the
rules of any stock exchange or quotation system on which Shares are listed or quoted, applicable to the taking or refraining from taking of any action under this Plan, including the administration of this Plan and the issuance or transfer of Awards
or Award Shares. 
 (d) “Award” means a Stock Award (e.g. restricted stock unit award), SAR, Cash Award, or Option
granted in accordance with the terms of this Plan. 
 (e) “Award Agreement” means the document evidencing the grant
of an Award. 
 (f) “Award Shares” means Shares covered by an outstanding Award or purchased under an Award. 

(g) “Awardee” means: (i) a person to whom an Award has been granted, including a holder of a Substitute Award,
(ii) a person to whom an Award has been transferred in accordance with all applicable requirements of Sections 6.5, 7(h), and 17. 
 (h)
“Board” means the Board of Directors of the Company. 
 (i) “Cash Award” means the right to
receive cash as described in Section 8.3. 
 (j) “Change in Control” means any transaction or event that the Board
specifies as a Change in Control under Section 10.4. 
 (k) “Code” means the Internal Revenue Code of 1986. 

(l) “Committee” means a committee composed of Company Directors appointed in accordance with the Company’s charter
documents and Section 4. 
 (m) “Company” means Avanir Pharmaceuticals, Inc., a Delaware corporation. 

 (n) “Company Director” means a member of the Board. 

(o) “Consultant” means an individual who, or an employee of any entity that, provides bona fide services to the Company
or an Affiliate not in connection with the offer or sale of securities in a capital-raising transaction, but who is not an Employee. 
 (p)
“Director” means a member of the Board of Directors of the Company or an Affiliate. 
 (q)
“Divestiture” means any transaction or event that the Board specifies as a Divestiture under Section 10.5. 
 (r)
“Domestic Relations Order” means a “domestic relations order” as defined in, and otherwise meeting the requirements of, Section 414(p) of the Code, except that reference to a “plan” in that definition
shall be to this Plan. 
 (s) “Effective Date” means the later of the date on which this Plan is approved by the
Company’s stockholders and the date on which this Plan is approved by the Board. 
 (t) “Employee” means a
regular employee of the Company or an Affiliate, including an officer or Director, who is treated as an employee in the personnel records of the Company or an Affiliate, but not individuals who are classified by the Company or an Affiliate as:
(i) leased from or otherwise employed by a third party, (ii) independent contractors, or (iii) intermittent or temporary workers. The Company’s or an Affiliate’s classification of an individual as an “Employee” (or
as not an “Employee”) for purposes of this Plan shall not be altered retroactively even if that classification is changed retroactively for another purpose as a result of an audit, litigation or otherwise. An Awardee shall not cease to be
an Employee due to transfers between locations of the Company, or between the Company and an Affiliate, or to any successor to the Company or an Affiliate that assumes the Awardee’s Options under Section 10. Neither service as a Director
nor receipt of a director’s fee shall be sufficient to make a Director an “Employee.” 
 (u) “Exchange
Act” means the Securities Exchange Act of 1934. 
 (v) “Executive” means, if the Company has any class
of any equity security registered under Section 12 of the Exchange Act, an individual who is subject to Section 16 of the Exchange Act or who is a “covered employee” under Section 162(m) of the Code, in either case because
of the individual’s relationship with the Company or an Affiliate. If the Company does not have any class of any equity security registered under Section 12 of the Exchange Act, “Executive” means any (i) Director,
(ii) officer elected or appointed by the Board, or (iii) beneficial owner of more than 10% of any class of the Company’s equity securities. 

(w) “Expiration Date” means, with respect to an Award, the date stated in the Award Agreement as the expiration date of
the Award or, if no such date is stated in the Award Agreement, then the last day of the maximum exercise period for the Award, disregarding the effect of an Awardee’s Termination or any other event that would shorten the life of the Award.

 (x) “Fair Market Value” means the value of Shares as determined under Section 18.2. 

(y) “Fundamental Transaction” means any transaction or event described in Section 10.3. 

(z) “Grant Date” means the date the Administrator approves the grant of an Award. However, if the Administrator
specifies that an Award’s Grant Date is a future date or the date on which a condition is satisfied, the Grant Date for such Award is that future date or the date that the condition is satisfied. 

(aa) “Incentive Stock Option” means an Option intended to qualify as an incentive stock option under Section 422
of the Code and designated as an Incentive Stock Option in the Award Agreement for that Option. 

  
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 (bb) “Non-statutory Option” means any Option other than an Incentive
Stock Option. 
 (cc) “Non Employee Director” means any person who is a member of the Board but is not an Employee of
the Company or any Affiliate of the Company and has not been an Employee of the Company or any Affiliate of the Company at any time during the preceding twelve months. Service as a Director does not in itself constitute employment for purposes of
this definition. 
 (dd) “Objectively Determinable Performance Condition” shall mean a performance condition
(i) that is established (A) at the time an Award is granted or (B) no later than the earlier of (1) 90 days after the beginning of the period of service to which it relates, or (2) before the elapse of 25% of the period of
service to which it relates, (ii) that is uncertain of achievement at the time it is established, and (iii) the achievement of which is determinable by a third party with knowledge of the relevant facts. Examples of measures that may be
used in Objectively Determinable Performance Conditions include net order dollars, net profit dollars, net profit growth, net revenue dollars, revenue growth, individual performance, earnings per share, return on assets, return on equity, and other
financial objectives, objective customer satisfaction indicators and efficiency measures, each with respect to the Company and/or an Affiliate or individual business unit. 

(ee) “Officer” means an officer of the Company as defined in Rule 16a-1 adopted under the Exchange Act. 

(ff) “Option” means a right to purchase Shares of the Company granted under this Plan. 

(gg) “Option Price” means the price payable under an Option for Shares, not including any amount payable in respect of
withholding or other taxes. 
 (hh) “Option Shares” means Shares covered by an outstanding Option or purchased under
an Option. 
 (ii) “Plan” means this 2005 Equity Incentive Plan of Avanir Pharmaceuticals, Inc. 

(jj) “Purchase Price” means the price payable under a Stock Award for Shares, not including any amount payable in
respect of withholding or other taxes. 
 (kk) “Rule 16b-3” means Rule 16b-3 adopted under Section 16(b) of the
Exchange Act. 
 (ll) “SAR” or “Stock Appreciation Right” means a right to receive cash based on a change
in the Fair Market Value of a specific number of Shares pursuant to an Award Agreement, as described in Section 8.1. 
 (mm)
“Securities Act” means the Securities Act of 1933. 
 (nn) “Share” means a share of the
common stock of the Company or other securities substituted for the common stock under Section 10. 
 (oo) “Stock
Award” means an offer by the Company to sell shares subject to certain restrictions pursuant to the Award Agreement as described in Section 8.2 or, as determined by the Committee, a notional account representing the right to be
paid an amount based on Shares. 
 (pp) “Substitute Award” means a Substitute Option, Substitute SAR or Substitute
Stock Award granted in accordance with the terms of this Plan. 
 (qq) “Substitute Option” means an Option granted in
substitution for, or upon the conversion of, an option granted by another entity to purchase equity securities in the granting entity. 

(rr) “Substitute SAR” means a SAR granted in substitution for, or upon the conversion of, a stock appreciation right
granted by another entity with respect to equity securities in the granting entity. 

  
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 (ss) “Substitute Stock Award” means a Stock Award granted in substitution
for, or upon the conversion of, a stock award granted by another entity to purchase equity securities in the granting entity. 
 (tt)
“Termination” means that the Awardee has ceased to be, with or without any cause or reason, an Employee, Director or Consultant. However, unless so determined by the Administrator, or otherwise provided in this Plan.
“Termination” shall not include a change in status from an Employee, Consultant or Director to another such status. An event that causes an Affiliate to cease being an Affiliate shall be treated as the “Termination” of that
Affiliate’s Employees, Directors, and Consultants. 
 2.2. Rules of Interpretation. Any reference to a
“Section,” without more, is to a Section of this Plan. Captions and titles are used for convenience in this Plan and shall not, by themselves, determine the meaning of this Plan. Except when otherwise indicated by the context, the singular
includes the plural and vice versa. Any reference to a statute is also a reference to the applicable rules and regulations adopted under that statute. Any reference to a statute, rule or regulation, or to a section of a statute, rule or regulation,
is a reference to that statute, rule, regulation, or section as amended from time to time, both before and after the Effective Date and including any successor provisions. 

3. Shares Subject to this Plan; Term of this Plan. 

3.1. Number of Award Shares. Subject to the provisions of Section 10.2 of this Plan, the maximum aggregate number of Shares
that may be sold under the Plan is 1,415,501 Shares, plus an annual increase on the first day of each of the Company’s fiscal years beginning in fiscal 2006 equal to the lesser of (a) 1% of the Shares outstanding on the last day of the
immediately preceding fiscal year, (b) 325,000 Shares, or (c) such lesser number of Shares as the Board shall determine. The number of Shares initially reserved for issuance over the term of this Plan shall be increased by those Shares
that are restored pursuant to the decision of the Board or Committee pursuant to Section 6.4(a) to deliver only such Shares as are necessary to award the net Share appreciation. Except as required by applicable law, Shares issuable pursuant to
outstanding Awards shall not reduce the number of Shares reserved for issuance under this Plan until the earlier of the date such Shares are vested pursuant to the terms of the applicable Award or the actual date of delivery of the Shares to the
Awardee. Also, if an Award later terminates or expires without having been exercised in full, the maximum number of shares that may be issued under this Plan shall be increased by the number of Shares that were covered by, but not purchased under,
that Award. By contrast, the repurchase of Shares by the Company shall not increase the maximum number of Shares that may be issued under this Plan. 

3.2. Source of Shares. Award Shares may be Shares that have never been issued or Shares that are outstanding and are acquired to
discharge the Company’s obligation to deliver Award Shares. 
 3.3. Term of this Plan. 

(a) This Plan shall be effective on, and Awards maybe granted under this Plan on and after the Effective Date. 

(b) Subject to the provisions of Section 14, Awards may be granted under this Plan for a period of ten years from the earlier of the date
on which the Board approves this Plan and the date the Company’s stockholders approve this Plan. Accordingly, Awards may not be granted under this Plan after the ten-year anniversary of the earlier of those dates. 

4. Administration. 
 4.1. General.

 (a) The Board shall have ultimate responsibility for administering this Plan. The Board may delegate certain of its responsibilities to a
Committee, which shall consist of at least two members of the Board. The Board or the Committee may further delegate its responsibilities to any Employee of the Company or any Affiliate. Where this Plan specifies that an action is to be taken or a
determination made by the Board, only the 

  
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Board may take that action or make that determination. Where this Plan specifies that an action is to be taken or a determination made by the Committee, only the Committee may take that action or
make that determination. Where this Plan references the “Administrator,” the action may be taken or determination made by the Board, the Committee, or other Administrator, but only to the extent of the authority delegated by the Board or
the Committee to that Administrator. However, only the Board or the Committee may approve grants of Awards to Executives, and an Administrator other than the Board or the Committee may grant Awards only within the guidelines established by the Board
or Committee. Moreover, all actions and determinations by any Administrator are subject to the provisions of this Plan. 
 (b) The Committee
shall consist of Company Directors who are “Non-Employee Directors” as defined in Rule 16b-3 and, after the expiration of any transition period permitted by Treasury Regulations Section 1.162-27(h)(3), who are “outside
directors” as defined in Section 162(m) of the Code. 
 4.2. Authority of the Board or the Committee. Subject to the
other provisions of this Plan, the Board or the Committee shall have the authority to: 
 (a) grant Awards, including Substitute
Awards; 
 (b) determine the Fair Market Value of Shares as set forth in Section 18.2; 

(c) determine the Option Price and the Purchase Price of Awards; 

(d) select the Awardees; 
 (e)
determine the times Awards are granted; 
 (f) determine the number of Shares subject to each Award; 

(g) determine the methods of payment that may be used to purchase Award Shares; 

(h) determine the methods of payment that may be used to satisfy withholding tax obligations; 

(i) determine the other terms of each Award, including but not limited to the time or times at which Awards may be exercised, whether and under
what conditions an Award is assignable, and whether an Option is a Non-statutory Option or an Incentive Stock Option; 
 (j) modify or amend
any Award; 
 (k) authorize any person to sign any Award Agreement or other document related to this Plan on behalf of the Company; 

(l) determine the form of any Award Agreement or other document related to this Plan, and whether that document, including signatures, may be
in electronic form; 
 (m) interpret this Plan and any Award Agreement or document related to this Plan; 

(n) correct any defect, remedy any omission, or reconcile any inconsistency in this Plan, any Award Agreement or any other document related to
this Plan; 
 (o) adopt, amend, and revoke rules and regulations under this Plan, including rules and regulations relating to sub-plans and
Plan addenda; 
 (p) adopt, amend, and revoke special rules and procedures which may be inconsistent with the terms of this Plan, set forth
(if the Administrator so chooses) in sub-plans regarding (for example) the operation and administration of this Plan and the terms of Awards, if and to the extent necessary or useful to accommodate
non-

  
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U.S. Applicable Laws and practices as they apply to Awards and Award Shares held by, or granted or issued to, persons working or resident outside of the United States or employed by Affiliates
incorporated outside the United States; 
 (q) determine whether a transaction or event should be treated as a Change in Control, a
Divestiture or neither; 
 (r) determine the effect of a Fundamental Transaction and, if the Board determines that a transaction or event
should be treated as a Change in Control or a Divestiture, then the effect of that Change in Control or Divestiture; and 
 (s) make all
other determinations the Administrator deems necessary or advisable for the administration of this Plan. 
 4.3. Scope of
Discretion. Subject to the provisions of this Section 4.3, on all matters for which this Plan confers the authority, right or power on the Board, the Committee, or other Administrator to make decisions, that body may make those decisions in
its sole and absolute discretion. Those decisions will be final, binding and conclusive. In making its decisions, the Board, Committee or other Administrator need not treat all persons eligible to receive Awards, all Awardees, all Awards or all
Award Shares the same way. Notwithstanding anything herein to the contrary, and except as provided in Section 14.3, the discretion of the Board, Committee or other Administrator is subject to the specific provisions and specific limitations of
this Plan, as well as all rights conferred on specific Awardees by Award Agreements and other agreements. 
 5. Persons Eligible to Receive
Awards. 
 5.1. Eligible Individuals. Awards (including Substitute Awards) may be granted to, and only to, Employees,
Directors and Consultants, including to prospective Employees, Directors and Consultants conditioned on the beginning of their service for the Company or an Affiliate. However, Incentive Stock Options may only be granted to Employees, as provided in
Section 7(g). 
 5.2. Section 162(m) Limitation. 

(a) Options and SARs. Subject to the provisions of this Section 5.2, for so long as the Company is a “publicly held
corporation” within the meaning of Section 162(m) of the Code: (i) no Employee may be granted one or more SARs and Options within any fiscal year of the Company under this Plan to purchase more than 125,000 Shares under Options or to
receive compensation calculated with reference to more than that number of Shares under SARs, subject to adjustment pursuant to Section 10, (ii) Options and SARs may be granted to an Executive only by the Committee (and, notwithstanding
anything to the contrary in Section 4.1(a), not by the Board). If an Option or SAR is cancelled without being exercised or if the Option Price of an Option is reduced, that cancelled or repriced Option or SAR shall continue to be counted
against the limit on Awards that my be granted to any individual under this Section 5.2. Notwithstanding the foregoing, a new Employee of the Company or an Affiliate shall be eligible to receive up to a maximum of 250,000 Shares under Options
in the calendar year which they commence employment, or such compensation calculated with reference to such number of Shares under SARs, subject to adjustment pursuant to Section 10. 

(b) Cash Awards and Stock Awards. Any Cash Award or Stock Award intended as “qualified performance-based compensation” within
the meaning of Section 162(m) of the Code must vest or become exercisable contingent on the achievement of one or more Objectively Determinable Performance Conditions. The Committee shall have the discretion to determine the time and manner of
compliance with Section 162(m) of the Code. 

  
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 6. Terms and Conditions of Options. 

6.1. Price. No Option may have an Option Price less than the greater of (i) 100% of the Fair Market Value of the Shares on
the Grant Date or (ii) the par value of the Shares, if any, on the Grant Date. The Option Price of an Incentive Stock Option shall also be subject to Section 7(f). 

6.2. Term. No Option shall be exercisable after its Expiration Date. No Option may have an Expiration Date that is more than ten
years after its Grant Date. Additional provisions regarding the term of Incentive Stock Options are provided in Sections 7(a) and 7(e). 

6.3. Vesting. Options shall be exercisable: (a) on the Grant Date, or (b) in accordance with a schedule related to the
Grant Date, the date the Optionee’s directorship, employment or consultancy begins, or a different date specified in the Option Agreement. Additional provisions regarding the vesting of Incentive Stock Options are provided in Section 7(c).
No Option granted to an individual who is subject to the overtime pay provisions of the Fair Labor Standards Act may be exercised before the expiration of six months after the Grant Date. 

6.4. Form and Method of Payment. 

(a) The Board or Committee shall determine the acceptable form and method of payment for exercising an Option. So long as variable accounting
pursuant to “APB 25” does not apply and the Board or Committee otherwise determines there is no material adverse accounting consequence at the time of exercise, the Board or Committee may require the delivery in Shares for the value of the
net appreciation of the Shares at the time of exercise over the exercise price. The difference between full number of Shares covered by the exercised portion of the Award and the number of Shares actually delivered shall be restored to the amount of
Shares reserved for issuance under Section 3.1. 
 (b) Acceptable forms of payment for all Option Shares are cash, check or wire
transfer, denominated in U.S. dollars except as specified by the Administrator for non-U.S. Employees or non-U.S. sub-plans. 
 (c) In
addition, the Administrator may permit payment to be made by any of the following methods: 
 (i) other Shares, or the designation of other
Shares, which (A) are “mature” shares for purposes of avoiding variable accounting treatment under generally accepted accounting principles (generally mature shares are those that have been owned by the Optionee for more than six
months on the date of surrender), and (B) have in the aggregate a Fair Market Value on the date of surrender at least equal to the Option Price of the Shares as to which the Option is being exercised; 

(ii) provided that a public market exists for the Shares, consideration received by the Company under a procedure under which a licensed
broker-dealer advances funds on behalf of an Optionee or sells Option Shares on behalf of an Optionee (a “Cashless Exercise Procedure”), provided that if the Company extends or arranges for the extension of credit to an
Optionee under any Cashless Exercise Procedure, no Officer or Director may participate in that Cashless Exercise Procedure; 
 (iii)
cancellation of any debt owed by the Company or any Affiliate to the Optionee by the Company including without limitation waiver of compensation due or accrued for services previously rendered to the Company; and 

(iv) any combination of the methods of payment permitted by any paragraph of this Section 6.4. 

(d) The Administrator may also permit any other form or method of payment for Option Shares permitted by Applicable Law. 

  
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 6.5. Nonassignability of Options. Except as determined by the Administrator and as
otherwise permitted by this Section 6.5, no Option shall be assignable or otherwise transferable by the Optionee except by will or by the laws of descent and distribution. Options may be transferred and exercised in accordance with a Domestic
Relations Order and may be exercised by a guardian or conservator appointed to act for the Optionee. Incentive Stock Options may only be assigned in compliance with Section 7(h). 

6.6. Substitute Options. The Board may cause the Company to grant Substitute Options in connection with the acquisition by the
Company or an Affiliate of equity securities of any entity (including by merger, tender offer, or other similar transaction) or of all or a portion of the assets of any entity. Any such substitution shall be effective on the effective date of the
acquisition. Substitute Options may be Non-statutory Options or Incentive Stock Options. Unless and to the extent specified otherwise by the Board, Substitute Options shall have the same terms and conditions as the options they replace, except that
(subject to the provisions of Section 10) Substitute Options shall be Options to purchase Shares rather than equity securities of the granting entity and shall have an Option Price determined by the Board. 

6.7. Repricings. 

Options may not be repriced, replaced or regranted through cancellation or modification without stockholder approval. 

7. Incentive Stock Options. 
 The
following rules apply only to Incentive Stock Options and only to the extent these rules are more restrictive than the rules that would otherwise apply under this Plan. With the consent of the Optionee, or where this Plan provides that an action may
be taken notwithstanding any other provision of this Plan, the Administrator may deviate from the requirements of this Section, notwithstanding that any Incentive Stock Option modified by the Administrator will thereafter be treated as a
Non-statutory Option. 
 (a) The Expiration Date of an Incentive Stock Option shall not be later than ten years from its Grant Date, with the
result that no Incentive Stock Option may be exercised after the expiration of ten years from its Grant Date. 
 (b) No Incentive Stock
Option may be granted more than ten years from the date this Plan was approved by the Board. 
 (c) Options intended to be incentive stock
options under Section 422 of the Code that are granted to any single Optionee under all incentive stock option plans of the Company and its Affiliates, including incentive stock options granted under this Plan, may not vest at a rate of more
than $100,000 in Fair Market Value of stock (measured on the grant dates of the options) during any calendar year. For this purpose, an option vests with respect to a given share of stock the first time its holder may purchase that share,
notwithstanding any right of the Company to repurchase that share. Unless the administrator of that option plan specifies otherwise in the related agreement governing the option, this vesting limitation shall be applied by, to the extent necessary
to satisfy this $100,000 rule, treating certain stock options that were intended to be incentive stock options under Section 422 of the Code as Non-statutory Options. The stock options or portions of stock options to be reclassified as
Non-statutory Options are those with the highest option prices, whether granted under this Plan or any other equity compensation plan of the Company or any Affiliate that permits that treatment. This Section 7(c) shall not cause an Incentive
Stock Option to vest before its original vesting date or cause an Incentive Stock Option that has already vested to cease to be vested. 

(d) In order for an Incentive Stock Option to be exercised for any form of payment other than those described in Section 6.4(b), that
right must be stated at the time of grant in the Option Agreement relating to that Incentive Stock Option. 
 (e) Any Incentive Stock Option
granted to a Ten Percent Stockholder, must have an Expiration Date that is not later than five years from its Grant Date, with the result that no such Option may be exercised after the expiration of five years from the Grant Date. A “Ten
Percent Stockholder” is any person who, directly or by 

  
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attribution under Section 424(d) of the Code, owns stock possessing more than ten percent of the total combined voting power of all classes of stock of the Company or of any Affiliate on the
Grant Date. 
 (f) The Option Price of an Incentive Stock Option shall never be less than the Fair Market Value of the Shares at the Grant
Date. The Option Price for the Shares covered by an Incentive Stock Option granted to a Ten Percent Stockholder shall never be less than 110% of the Fair Market Value of the Shares at the Grant Date. 

(g) Incentive Stock Options may be granted only to Employees. If an Optionee changes status from an Employee to a Consultant, that
Optionee’s Incentive Stock Options become Non-statutory Options if not exercised within the time period described in Section 7(i) (determined by treating that change in status as a Termination solely for purposes of this
Section 7(g)). 
 (h) No rights under an Incentive Stock Option may be transferred by the Optionee, other than by will or the laws of
descent and distribution. During the life of the Optionee, an Incentive Stock Option may be exercised only by the Optionee. The Company’s compliance with a Domestic Relations Order, or the exercise of an Incentive Stock Option by a guardian or
conservator appointed to act for the Optionee, shall not violate this Section 7(h). 
 (i) An Incentive Stock Option shall be treated as
a Non-statutory Option if it remains exercisable after, and is not exercised within, the three-month period beginning with the Optionee’s Termination for any reason other than the Optionee’s death or disability (as defined in
Section 22(e) of the Code). In the case of Termination due to death, an Incentive Stock Option shall continue to be treated as an Incentive Stock Option if it remains exercisable after, and is not exercised within, the three month period after
the Optionee’s Termination provided it is exercised before the Expiration Date. In the case of Termination due to disability, an Incentive Stock Option shall be treated as a Non-statutory Option if it remains exercisable after, and is not
exercised within, one year after the Optionee’s Termination. 
 (j) An Incentive Stock Option may only be modified by the Board. 

8. Stock Appreciation Rights, Stock Awards and Cash Awards. 

8.1. Stock Appreciation Rights. 

(a) General. SARs may be granted either alone, in addition to, or in tandem with other Awards granted under this
Plan. The Administrator may grant SARs to eligible participants subject to terms and conditions not inconsistent with this Plan and determined by the Administrator. The specific terms and conditions applicable to the Awardee shall be provided for in
the Award Agreement. SARs shall be exercisable, in whole or in part, at such times as the Administrator shall specify in the Award Agreement. The grant or vesting of a SAR may be made contingent on the achievement of Objectively Determinable
Performance Conditions. 
 (b) Exercise of SARs. Upon the exercise of an SAR, in whole or in part, an Awardee
shall be entitled to a payment in an amount equal to the excess of the Fair Market Value of a fixed number of Shares covered by the exercised portion of the SAR on the date of exercise, over the Fair Market Value of the Shares covered by the
exercised portion of the SAR on the Grant Date. The amount due to the Awardee upon the exercise of a SAR shall be paid in Shares over the period or periods specified in the Award Agreement. An Award Agreement may place limits on the amount that may
be paid over any specified period or periods upon the exercise of a SAR, on an aggregate basis or as to any Awardee. A SAR shall be considered exercised when the Company receives written notice of exercise in accordance with the terms of the Award
Agreement from the person entitled to exercise the SAR. If a SAR has been granted in tandem with an Option, upon the exercise of the SAR, the number of shares that may be purchased pursuant to the Option shall be reduced by the number of shares with
respect to which the SAR is exercised. 
 (c) Nonassignability of SARs. Except as determined by the
Administrator, no SAR shall be assignable or otherwise transferable by the Awardee except by will or by the laws of descent and distribution, provided, however, that SARs may be transferred and exercised in accordance with a Domestic Relations
Order. 

  
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 (d) Substitute SARs. The Board may cause the Company to grant Substitute SARs in
connection with the acquisition by the Company or an Affiliate of equity securities of any entity (including by merger) or all or a portion of the assets of any entity. Any such substitution shall be effective on the effective date of the
acquisition. Unless and to the extent specified otherwise by the Board, Substitute SARs shall have the same terms and conditions as the options they replace, except that (subject to the provisions of Section 9) Substitute SARs shall be
exercisable with respect to the Fair Market Value of Shares rather than equity securities of the granting entity and shall be on terms that, as determined by the Board in its sole and absolute discretion, properly reflects the substitution. 

(e) Repricings. A SAR may not be repriced, replaced or regranted, through cancellation or modification without stockholder
approval. 
 8.2. Stock Awards. General. The specific terms and conditions of a Stock Award
applicable to the Awardee shall be provided for in the Award Agreement. The Award Agreement shall state the number of Shares that the Awardee shall be entitled to receive or purchase, the terms and conditions on which the Shares shall vest, the
price to be paid, whether Shares are to be delivered at the time of grant or at some deferred date specified in the Award Agreement (e.g. a restricted stock unit award agreement), whether the Award is payable solely in Shares, cash or either and, if
applicable, the time within which the Awardee must accept such offer. The offer shall be accepted by execution of the Award Agreement. The Administrator may require that all Shares subject to a right of repurchase or risk of forfeiture be held in
escrow until such repurchase right or risk of forfeiture lapses. The grant or vesting of a Stock Award may be made contingent on the achievement of Objectively Determinable Performance Conditions. 

(b) Right of Repurchase. If so provided in the Award Agreement, Award Shares acquired pursuant to a Stock Award may be subject to
repurchase by the Company or an Affiliate if not vested in accordance with the Award Agreement. 
 (c) Form of Payment. The
Administrator shall determine the acceptable form and method of payment for exercising a Stock Award. Acceptable forms of payment for all Award Shares are cash, check or wire transfer, denominated in U.S. dollars except as specified by the
Administrator for non-U.S. sub-plans. In addition, the Administrator may permit payment to be made by any of the methods permitted with respect to the exercise of Options pursuant to Section 6.4. 

(d) Nonassignability of Stock Awards. Except as determined by the Administrator, no Stock Award shall be assignable or otherwise
transferable by the Awardee except by will or by the laws of descent and distribution, provided, however, that Stock Awards may be transferred and exercised in accordance with a Domestic Relations Order. 

(e) Substitute Stock Award. The Board may cause the Company to grant Substitute Stock Awards in connection with the acquisition
by the Company or an Affiliate of equity securities of any entity (including by merger) or all or a portion of the assets of any entity. Unless and to the extent specified otherwise by the Board, Substitute Stock Awards shall have the same terms and
conditions as the stock awards they replace, except that (subject to the provisions of Section 10) Substitute Stock Awards shall be Stock Awards to purchase Shares rather than equity securities of the granting entity and shall have a Purchase
Price that, as determined by the Board in its sole and absolute discretion, properly reflects the substitution. Any such Substituted Stock Award shall be effective on the effective date of the acquisition. 

8.3. Cash Awards. 

Cash Awards may be granted either alone, in addition to, or in tandem with other Awards granted under this Plan. After the Administrator
determines that it will offer a Cash Award, it shall advise the Awardee, by means of an Award Agreement, of the terms, conditions and restrictions related to the Cash Award. 

  
 -10- 

 9. Exercise of Awards. 

9.1. In General. An Award shall be exercisable in accordance with this Plan and the Award Agreement under which it is granted.

 9.2. Time of Exercise. Options and Stock Awards shall be considered exercised when the Company receives:
(a) written notice of exercise from the person entitled to exercise the Option or Stock Award, (b) full payment, or provision for payment, in a form and method approved by the Administrator, for the Shares for which the Option or Stock
Award is being exercised, and (c) with respect to Non-statutory Options, payment, or provision for payment, in a form approved by the Administrator, of all applicable withholding taxes due upon exercise. An Award may not be exercised for a
fraction of a Share. SARs shall be considered exercised when the Company receives written notice of the exercise from the person entitled to exercise the SAR. 

9.3. Issuance of Award Shares. The Company shall issue Award Shares in the name of the person properly exercising the Award. If
the Awardee so requests, the Award Shares shall be issued in the name of the Awardee and the Awardee’s spouse. The Company shall endeavor to issue Award Shares promptly after an Award is exercised or after the Grant Date of a Stock Award, as
applicable. Until Award Shares are actually issued, as evidenced by the appropriate entry on the stock register of the Company or its transfer agent, the Awardee will not have the rights of a stockholder with respect to those Award Shares, even
though the Awardee has completed all the steps necessary to exercise the Award. No adjustment shall be made for any dividend, distribution, or other right for which the record date precedes the date the Award Shares are issued, except as provided in
Section 10. 
 9.4. Termination. 

(a) In General. Except as provided in an Award Agreement or in writing by the Administrator, including in an Award Agreement, and
as otherwise provided in Sections 9.4(b), (c), (d) and (e) after an Awardee’s Termination, the Awardee’s Awards shall be exercisable to the extent (but only to the extent) they are vested on the date of that Termination and only
during the three months after the Termination, but in no event after the Expiration Date. To the extent the Awardee does not exercise an Award within the time specified for exercise, the Award shall automatically terminate. 

(b) Leaves of Absence. Unless otherwise provided in the Award Agreement, no Award may be exercised more than three months after
the beginning of a leave of absence, other than a personal or medical leave approved by an authorized representative of the Company with employment guaranteed upon return. Awards shall not continue to vest during a leave of absence, unless otherwise
determined by the Administrator with respect to an approved personal or medical leave with employment guaranteed upon return. 
 (c)
Death or Disability. Unless otherwise provided by the Administrator, if an Awardee’s Termination is due to death or disability (as determined by the Administrator with respect to all Awards other than Incentive Stock Options and
as defined by Section 422(e) of the Code with respect to Incentive Stock Options), all Awards of that Awardee to the extent exercisable at the date of that Termination may be exercised for one year after that Termination, but in no event after
the Expiration Date. In the case of Termination due to death, an Award may be exercised as provided in Section 17. In the case of Termination due to disability, if a guardian or conservator has been appointed to act for the Awardee and been
granted this authority as part of that appointment, that guardian or conservator may exercise the Award on behalf of the Awardee. Death or disability occurring after an Awardee’s Termination shall not cause the Termination to be treated as
having occurred due to death or disability. To the extent an Award is not so exercised within the time specified for its exercise, the Award shall automatically terminate. 

(d) Divestiture. If an Awardee’s Termination is due to a Divestiture, the Board may take any one or more of the actions
described in Section 10.3 or 10.4 with respect to the Awardee’s Awards. 
 (e) Administrator Discretion.
Notwithstanding the provisions of Section 9.4 (a)-(d), the Plan Administrator shall have complete discretion, exercisable either at the time an Award is granted or at any time while the Award remains outstanding, to: 

  
 -11- 

 (i) Extend the period of time for which the Award is to remain exercisable, following the
Awardee’s Termination, from the limited exercise period otherwise in effect for that Award to such greater period of time as the Administrator shall deem appropriate, but in no event beyond the Expiration Date; and/or 

(ii) Permit the Award to be exercised, during the applicable post-Termination exercise period, not only with respect to the number of vested
Shares for which such Award may be exercisable at the time of the Awardee’s Termination but also with respect to one or more additional installments in which the Awardee would have vested had the Awardee not been subject to Termination. 

(f) Consulting or Employment Relationship. Nothing in this Plan or in any Award Agreement, and no Award or the fact that Award
Shares remain subject to repurchase rights, shall: (A) interfere with or limit the right of the Company or any Affiliate to terminate the employment or consultancy of any Awardee at any time, whether with or without cause or reason, and with or
without the payment of severance or any other compensation or payment, or (B) interfere with the application of any provision in any of the Company’s or any Affiliate’s charter documents or Applicable Law relating to the election,
appointment, term of office, or removal of a Director. 
 10. Certain Transactions and Events. 

10.1. In General. Except as provided in this Section 10, no change in the capital structure of the Company, merger, sale or
other disposition of assets or a subsidiary, change in control, issuance by the Company of shares of any class of securities or securities convertible into shares of any class of securities, exchange or conversion of securities, or other transaction
or event shall require or be the occasion for any adjustments of the type described in this Section 10. Additional provisions with respect to the foregoing transactions are set forth in Section 14.3. 

10.2. Changes in Capital Structure. In the event of any stock split, reverse stock split, recapitalization, combination or
reclassification of stock, stock dividend, spin-off, extraordinary cash or other property dividend or similar change to the capital structure of the Company (not including a Fundamental Transaction or Change in Control), the Board shall make
whatever adjustments it concludes are appropriate to: (a) the number and type of Awards that may be granted under this Plan, (b) the number and type of Options that may be granted to any individual under this Plan, (c) the terms of
any SAR, (d) the Purchase Price of any Stock Award, (e) the Option Price and number and class of securities issuable under each outstanding Option, and (f) the repurchase price of any securities substituted for Award Shares that are
subject to repurchase rights. The specific adjustments shall be determined by the Board. Unless the Board specifies otherwise, any securities issuable as a result of any such adjustment shall be rounded down to the next lower whole security. The
Board need not adopt the same rules for each Award or each Awardee. 
 10.3. Fundamental
Transactions. Except for grants to Non-Employee Directors pursuant to Section 11 herein, in the event of (a) a merger or consolidation in which the Company is not the surviving corporation (other than a merger or
consolidation with a wholly-owned subsidiary, a reincorporation of the Company in a different jurisdiction, or other transaction in which there is no substantial change in the stockholders of the Company or their relative stock holdings and the
Awards granted under this Plan are assumed, converted or replaced by the successor corporation, which assumption shall be binding on all Participants), (b) a merger in which the Company is the surviving corporation but after which the
stockholders of the Company immediately prior to such merger (other than any stockholder that merges, or which owns or controls another corporation that merges, with the Company in such merger) cease to own their shares or other equity interest in
the Company, (c) the sale of all or substantially all of the assets of the Company, or (d) the acquisition, sale, or transfer of more than 50% of the outstanding shares of the Company by tender offer or similar transaction (each, a
“Fundamental Transaction”), any or all outstanding Awards may be assumed, converted or replaced by the successor corporation (if any), which assumption, conversion or replacement shall be binding on all participants under
this Plan. In the alternative, the successor corporation may substitute equivalent Awards or provide substantially similar consideration to participants as was provided to stockholders (after taking into account the existing provisions of the
Awards). The successor corporation may also issue, in place of outstanding Shares held by the participants, substantially similar shares or other property subject to repurchase restrictions no less favorable to the participant. In the event such
successor corporation (if any) does not assume or substitute Awards, as provided above, pursuant to a transaction described in this Subsection 10.3, the  

  
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vesting with respect to such Awards shall fully and immediately accelerate or the repurchase rights of the Company shall fully and immediately terminate, as the case may be, so that the Awards
may be exercised or the repurchase rights shall terminate before, or otherwise in connection with the closing or completion of the Fundamental Transaction or event, but then terminate. Notwithstanding anything in this Plan to the contrary, the
Committee may, in its sole discretion, provide that the vesting of any or all Award Shares subject to vesting or right of repurchase shall accelerate or lapse, as the case may be, upon a transaction described in this Section 10.3. If the
Committee exercises such discretion with respect to Options, such Options shall become exercisable in full prior to the consummation of such event at such time and on such conditions as the Committee determines, and if such Options are not exercised
prior to the consummation of the Fundamental Transaction, they shall terminate at such time as determined by the Committee. Subject to any greater rights granted to participants under the foregoing provisions of this Section 10.3, in the event
of the occurrence of any Fundamental Transaction, any outstanding Awards shall be treated as provided in the applicable agreement or plan of merger, consolidation, dissolution, liquidation, or sale of assets. 

10.4. Changes of Control. The Board may also, but need not, specify that other transactions or
events constitute a “Change in Control”. The Board may do that either before or after the transaction or event occurs. Examples of transactions or events that the Board may treat as Changes of Control are: (a) any person
or entity, including a “group” as contemplated by Section 13(d)(3) of the Exchange Act, acquires securities holding 50% or more of the total combined voting power or value of the Company, or (b) as a result of or in connection
with a contested election of Company Directors, the persons who were Company Directors immediately before the election cease to constitute a majority of the Board. In connection with a Change in Control, notwithstanding any other provision of this
Plan, the Board may, but need not, take any one or more of the actions described in Section 10.3. In addition, the Board may extend the date for the exercise of Awards (but not beyond their original Expiration Date). The Board need not adopt
the same rules for each Award or each Awardee. Notwithstanding anything in this Plan to the contrary, in the event of an involuntary Termination of services for any reason other than death, disability or Cause, within 12 months following the
consummation of a Fundamental Transaction or Change in Control, any Awards, assumed or substituted in a Fundamental Transaction or Change in Control, that are subject to vesting conditions and/or the right of repurchase in favor of the Company or a
successor entity, shall accelerate fully so that such Award Shares are immediately exercisable upon Termination or, if subject to the right of repurchase in favor of the Company, such repurchase rights shall lapse as of the date of Termination. Such
Awards shall be exercisable for a period of three months following termination. 
 10.5. Divestiture. If the
Company or an Affiliate sells or otherwise transfers equity securities of an Affiliate to a person or entity other than the Company or an Affiliate, or leases, exchanges or transfers all or any portion of its assets to such a person or entity, then
the Board may specify that such transaction or event constitutes a “Divestiture”. In connection with a Divestiture, notwithstanding any other provision of this Plan, the Board may, but need not, take one or more
of the actions described in Section 10.3 or 10.4 with respect to Awards of Award Shares held by, for example, Employees, Directors or Consultants for whom that transaction or event results in a Termination. The Board need not adopt the same
rules for each Award or Awardee. 
 10.6. Dissolution. If the Company adopts a plan of dissolution, the Board may cause
Awards to be fully vested and exercisable (but not after their Expiration Date) before the dissolution is completed but contingent on its completion and may cause the Company’s repurchase rights on Award Shares to lapse upon completion of the
dissolution. The Board need not adopt the same rules for each Award or each Awardee. Notwithstanding anything herein to the contrary, in the event of a dissolution of the Company, to the extent not exercised before the earlier of the completion of
the dissolution or their Expiration Date, Awards shall terminate immediately prior to the dissolution. 

  
 -13- 

 10.7. Cut-Back to Preserve Benefits. If the Administrator determines that the net
after-tax amount to be realized by any Awardee, taking into account any accelerated vesting, termination of repurchase rights, or cash payments to that Awardee in connection with any transaction or event set forth in this Section 10 would be
greater if one or more of those steps were not taken or payments were not made with respect to that Awardee’s Awards or Award Shares, then, at the election of the Awardee, to such extent, one or more of those steps shall not be taken and
payments shall not be made. 
 11. Non-Employee Director Awards. 

11.1. Non-Employee Director Awards. 

(a) General. Except as otherwise determined by the Committee, Non-Employee Directors will automatically receive Options as set forth
below. 
 (i) Non-Employee Directors initially elected to the Board on or after the Effective Date will, at that time, automatically receive
an Option to purchase 6,250 Shares at a price equal to 100% the Fair Market Value on the Grant Date, such Option to have a ten-year term and to vest and become exercisable with respect to one-third of the underlying Shares on the first anniversary
of the Grant Date and then with respect to one-twelfth of the underlying shares quarterly thereafter. 
 (ii) Immediately following each
annual meeting of stockholders held on or after the Effective Date, Non-Employee Directors who have then served on the Board for at least six months will automatically receive an Option to purchase 2,500 Shares at a price equal to 100% the Fair
Market Value on the Grant Date, such Option to have a ten-year term and to be fully vested and exercisable on the Grant Date. 
 (b)
Termination of Service. The following provisions shall govern the exercise of any Awards granted pursuant to Section 11.1 held by the Awardee at the time the Awardee ceases to serve as a Non-Employee Director, Employee or Consultant:

 (i) In General. Except as otherwise provided in Section 10.3, after cessation of service (the
“Cessation Date”), the Awardee’s Awards shall be exercisable to the extent (but only to the extent) they are vested on the Cessation Date and only during the one year after such Cessation
Date, but in no event after the Expiration Date. To the extent the Awardee does not exercise an Award within the time specified for exercise, the Award shall automatically terminate. 

(ii) Death or Disability. If an Awardee’s cessation of service is due to death or disability (as determined by the Board),
all Awards of that Awardee, to the extent exercisable upon such Cessation Date, may be exercised for one year after the Cessation Date, but in no event after the Expiration Date. In the case of a cessation of service due to death, an Award may be
exercised as provided in Section 16. In the case of a cessation of service due to disability, if a guardian or conservator has been appointed to act for the Awardee and been granted this authority as part of that appointment, that guardian or
conservator may exercise the Award on behalf of the Awardee. Death or disability occurring after an Awardee’s cessation of service shall not cause the cessation of service to be treated as having occurred due to death or disability. To the
extent an Award is not so exercised within the time specified for its exercise, the Award shall automatically terminate. 
 (c) Board
Discretion. The Awards under this Section 11.1 are not intended as the exclusive Awards that may be made to Non-Employee Directors under this Plan. The Board may, in its discretion, amend the Plan with respect to the terms of the Awards
herein, may add or substitute other Awards or may temporarily or permanently suspend Awards hereunder, all without approval of the Company’s stockholders. 

  
 -14- 

 11.2. Certain Transactions and Events. 

(a) In the event of a Fundamental Transaction while the Awardee remains a Non-Employee Director, the Shares at the time subject to each
outstanding Option held by such Awardee pursuant to Section 11, but not otherwise vested, shall automatically vest in full so that each such Option shall, immediately prior to the effective date of the Fundamental Transaction, become
exercisable for all the Shares as fully vested Shares and may be exercised for any or all of those vested Shares. Immediately following the consummation of the Fundamental Transaction, each Option shall terminate and cease to be outstanding, except
to the extent assumed by the successor corporation (or Affiliate thereof). 
 (b) In the event of a Change in Control while the Awardee
remains a Non-Employee Director, the Shares at the time subject to each outstanding Option held by such Awardee pursuant to Section 11, but not otherwise vested, shall automatically vest in full so that each such Option shall, immediately prior
to the effective date of the Change in Control, become exercisable for all the Shares as fully vested Shares and may be exercised for any or all of those vested Shares. Each such Option shall remain exercisable for such fully vested Shares until the
expiration or sooner termination of the Option term in connection with a Change in Control. 
 (c) Each Option which is assumed in connection
with a Fundamental Transaction shall be appropriately adjusted, immediately after such Fundamental Transaction, to apply to the number and class of securities which would have been issuable to the Awardee in consummation of such Fundamental
Transaction had the Option been exercised immediately prior to such Fundamental Transaction. Appropriate adjustments shall also be made to the Option Price payable per share under each outstanding Option, provided the aggregate Option Price payable
for such securities shall remain the same. To the extent the actual holders of the Company’s outstanding common stock receive cash consideration for their common stock in consummation of the Fundamental Transaction, the successor corporation
may, in connection with the assumption of the outstanding Options granted pursuant to Section 11, substitute one or more shares of its own common stock with a fair market value equivalent to the cash consideration paid per share of common stock
in such Fundamental Transaction. 
 (d) The grant of Options pursuant to Section 11 shall in no way affect the right of the Company to
adjust, reclassify, reorganize or otherwise change its capital or business structure or to merge, consolidate, dissolve, liquidate or sell or transfer all or any part of its business or assets. 

(e) The remaining terms of each Option granted pursuant to Section 11 shall, as applicable, be the same as terms in effect for Awards
granted under this Plan, provided that the provisions of Section 9.4 and Section 10 shall not apply to Options granted pursuant to Section 11. 

11.3. Limited Transferability of Options. Each Option granted pursuant to Section 11 may be assigned in whole or in part
during the Awardee’s lifetime to one or more members of the Awardee’s family or to a trust established exclusively for one or more such family members or to an entity in which the Awardee is majority owner or to the Awardee ‘s former
spouse, to the extent such assignment is in connection with the Awardee ‘s estate or financial plan or pursuant to a Domestic Relations Order. The assigned portion may only be exercised by the person or persons who acquire a proprietary
interest in the Option pursuant to the assignment. The terms applicable to the assigned portion shall be the same as those in effect for the Option immediately prior to such assignment and shall be set forth in such documents issued to the assignee
as the Administrator may deem appropriate. The Awardee may also designate one or more persons as the beneficiary or beneficiaries of his or her outstanding Options under Section 11, and those Options shall, in accordance with such designation,
automatically be transferred to such beneficiary or beneficiaries upon the Awardee ‘s death while holding those Options. Such beneficiary or beneficiaries shall take the transferred Options subject to all the terms and conditions of the
applicable Award Agreement evidencing each such transferred Option, including (without limitation) the limited time period during which the Option may be exercised following the Awardee ‘s death. 

  
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 12. Withholding and Tax Reporting. 

12.1. Tax Withholding Alternatives. 

(a) General. Whenever Award Shares are issued or become free of restrictions, the Company may require the Awardee to remit to the
Company an amount sufficient to satisfy any applicable tax withholding requirement, whether the related tax is imposed on the Awardee or the Company. The Company shall have no obligation to deliver Award Shares or release Award Shares from an escrow
or permit a transfer of Award Shares until the Awardee has satisfied those tax withholding obligations. Whenever payment in satisfaction of Awards is made in cash, the payment will be reduced by an amount sufficient to satisfy all tax withholding
requirements. 
 (b) Method of Payment. The Awardee shall pay any required withholding using the forms of consideration
described in Section 6.4(b), except that, in the discretion of the Administrator, the Company may also permit the Awardee to use any of the forms of payment described in Section 6.4(c). The Administrator, in its sole discretion, may also
permit Award Shares to be withheld to pay required withholding. If the Administrator permits Award Shares to be withheld, the Fair Market Value of the Award Shares withheld, as determined as of the date of withholding, shall not exceed the amount
determined by the applicable minimum statutory withholding rates. 
 12.2. Reporting of Dispositions. Any holder of Option
Shares acquired under an Incentive Stock Option shall promptly notify the Administrator, following such procedures as the Administrator may require, of the sale or other disposition of any of those Option Shares if the disposition occurs during:
(a) the longer of two years after the Grant Date of the Incentive Stock Option and one year after the date the Incentive Stock Option was exercised, or (b) such other period as the Administrator has established. 

13. Compliance with Law. 
 The grant of
Awards and the issuance and subsequent transfer of Award Shares shall be subject to compliance with all Applicable Law, including all applicable securities laws. Awards may not be exercised, and Award Shares may not be transferred, in violation of
Applicable Law. Thus, for example, Awards may not be exercised unless: (a) a registration statement under the Securities Act is then in effect with respect to the related Award Shares, or (b) in the opinion of legal counsel to the Company,
those Award Shares may be issued in accordance with an applicable exemption from the registration requirements of the Securities Act and any other applicable securities laws. The failure or inability of the Company to obtain from any regulatory body
the authority considered by the Company’s legal counsel to be necessary or useful for the lawful issuance of any Award Shares or their subsequent transfer shall relieve the Company of any liability for failing to issue those Award Shares or
permitting their transfer. As a condition to the exercise of any Award or the transfer of any Award Shares, the Company may require the Awardee to satisfy any requirements or qualifications that may be necessary or appropriate to comply with or
evidence compliance with any Applicable Law. 
 14. Amendment or Termination of this Plan or Outstanding Awards. 

14.1. Amendment and Termination. Subject to the provisions of Section 14.2, the Board may at any time amend, suspend, or
terminate this Plan. 
 14.2. Stockholder Approval. The Company shall obtain the approval of the Company’s
stockholders for any amendment to this Plan if stockholder approval is necessary to comply with any Applicable Law or with the requirements applicable to the grant of Awards intended to be Incentive Stock Options. The Board may also, but need not,
require that the Company’s stockholders approve any other amendments to this Plan. 

  
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 14.3. Effect. No amendment, suspension, or termination of this Plan, and no
modification of any Award even in the absence of an amendment, suspension, or termination of this Plan, shall impair any existing contractual rights of any Awardee unless the affected Awardee consents to the amendment, suspension, termination, or
modification. Notwithstanding anything herein to the contrary, no such consent shall be required if the Board determines, in its sole and absolute discretion, that the amendment, suspension, termination, or modification: (a) is required or
advisable in order for the Company, this Plan or the Award to satisfy Applicable Law, to meet the requirements of any accounting standard or to avoid any adverse accounting treatment, or (b) in connection with any transaction or event described
in Section 10, is in the best interests of the Company or its stockholders. The Board may, but need not, take the tax or accounting consequences to affected Awardees into consideration in acting under the preceding sentence. Those decisions
shall be final, binding and conclusive. Termination of this Plan shall not affect the Administrator’s ability to exercise the powers granted to it under this Plan with respect to Awards granted before the termination of Award Shares issued
under such Awards even if those Award Shares are issued after the termination. 
 15. Reserved Rights. 

15.1. Nonexclusivity of this Plan. This Plan shall not limit the power of the Company or any Affiliate to adopt other incentive
arrangements including, for example, the grant or issuance of stock options, stock, or other equity-based rights under other plans. 

15.2. Unfunded Plan. This Plan shall be unfunded. Although bookkeeping accounts may be established with respect to Awardees, any
such accounts will be used merely as a convenience. The Company shall not be required to segregate any assets on account of this Plan, the grant of Awards, or the issuance of Award Shares. The Company and the Administrator shall not be deemed to be
a trustee of stock or cash to be awarded under this Plan. Any obligations of the Company to any Awardee shall be based solely upon contracts entered into under this Plan, such as Award Agreements. No such obligations shall be deemed to be secured by
any pledge or other encumbrance on any assets of the Company. Neither the Company nor the Administrator shall be required to give any security or bond for the performance of any such obligations. 

16. Special Arrangements Regarding Award Shares. 

16.1. Escrow of Stock Certificates. To enforce any restrictions on Award Shares, the Administrator may require their holder to
deposit the certificates representing Award Shares, with stock powers or other transfer instruments approved by the Administrator endorsed in blank, with the Company or an agent of the Company to hold in escrow until the restrictions have lapsed or
terminated. The Administrator may also cause a legend or legends referencing the restrictions to be placed on the certificates. 

16.2. Repurchase Rights. 

(a) General. If a Stock Award is subject to vesting conditions, the Company shall have the right, during the seven months after
the Awardee’s Termination, to repurchase any or all of the Award Shares that were unvested as of the date of that Termination. The repurchase price shall be determined by the Administrator in accordance with this Section 16.2 which shall
be either (i) the Purchase Price for the Award Shares (minus the amount of any cash dividends paid or payable with respect to the Award Shares for which the record date precedes the repurchase) or (ii) the lower of (A) the Purchase
Price for the Shares or (B) the Fair Market Value of those Award Shares as of the date of the Termination. The repurchase price shall be paid in cash. The Company may assign this right of repurchase. 

(b) Procedure. The Company or its assignee may choose to give the Awardee a written notice of exercise of its repurchase rights
under this Section 16.2. However, the Company’s failure to give such a notice shall not affect its rights to repurchase Award Shares. The Company must, however, tender the repurchase price during the period specified in this
Section 16.2 for exercising its repurchase rights in order to exercise such rights. 

  
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 17. Beneficiaries. 

An Awardee may file a written designation of one or more beneficiaries who are to receive the Awardee’s rights under the Awardee’s
Awards after the Awardee’s death. An Awardee may change such a designation at any time by written notice. If an Awardee designates a beneficiary, the beneficiary may exercise the Awardee’s Awards after the Awardee’s death. If an
Awardee dies when the Awardee has no living beneficiary designated under this Plan, the Company shall allow the executor or administrator of the Awardee’s estate to exercise the Award or, if there is none, the person entitled to exercise the
Option under the Awardee’s will or the laws of descent and distribution. In any case, no Award may be exercised after its Expiration Date. 
 18.
Miscellaneous. 
 18.1. Governing Law. This Plan, the Award Agreements and all other agreements entered into under this
Plan, and all actions taken under this Plan or in connection with Awards or Award Shares, shall be governed by the laws of the State of California. 

18.2. Determination of Value. Fair Market Value shall be determined as follows: 

(a) Listed Stock. If the Shares are traded on any established stock exchange or quoted on a national market system, Fair Market
Value shall be the closing sales price for the Shares as quoted on that stock exchange or system for the date the value is to be determined (the “Value Date”) as reported in The Wall Street Journal or a similar
publication. If no sales are reported as having occurred on the Value Date, Fair Market Value shall be that closing sales price for the last preceding trading day on which sales of Shares are reported as having occurred. If no sales are reported as
having occurred during the five trading days before the Value Date, Fair Market Value shall be the closing bid for Shares on the Value Date. If Shares are listed on multiple exchanges or systems, Fair Market Value shall be based on sales or bid
prices on the primary exchange or system on which Shares are traded or quoted. 
 (b) Stock Quoted by Securities Dealer. If
Shares are regularly quoted by a recognized securities dealer but selling prices are not reported on any established stock exchange or quoted on a national market system, Fair Market Value shall be the mean between the high bid and low asked prices
on the Value Date. If no prices are quoted for the Value Date, Fair Market Value shall be the mean between the high bid and low asked prices on the last preceding trading day on which any bid and asked prices were quoted. 

(c) No Established Market. If Shares are not traded on any established stock exchange or quoted on a national market system and
are not quoted by a recognized securities dealer, the Administrator (following guidelines established by the Board or Committee) will determine Fair Market Value in good faith. The Administrator will consider the following factors, and any others it
considers significant, in determining Fair Market Value: (i) the price at which other securities of the Company have been issued to purchasers other than Employees, Directors, or Consultants, (ii) the Company’s stockholder’s
equity, prospective earning power, dividend-paying capacity, and non-operating assets, if any, and (iii) any other relevant factors, including the economic outlook for the Company and the Company’s industry, the Company’s position in
that industry, the Company’s goodwill and other intellectual property, and the values of securities of other businesses in the same industry. 

18.3. Reservation of Shares. During the term of this Plan, the Company shall at all times reserve and keep available such number
of Shares as are still issuable under this Plan. 
 18.4. Electronic Communications. Any Award Agreement, notice of
exercise of an Award, or other document required or permitted by this Plan may be delivered in writing or, to the extent determined by the Administrator, electronically. Signatures may also be electronic if permitted by the Administrator.

 18.5. Notices. Unless the Administrator specifies otherwise, any notice to the Company under any Option Agreement or
with respect to any Awards or Award Shares shall be in writing (or, if so authorized by Section 18.4, communicated electronically), shall be addressed to the Secretary of the Company, and shall only be effective when received by the Secretary
of the Company. 

  
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*            *           
 * 
 Approved by stockholders: March 17, 2005 

Amended: February 6, 2006 
 Amended: March 23, 2009

  
 -19-EX-10.29

 Exhibit 10.29 

FIRST AMENDMENT TO 

SUMMIT OFFICE LEASE 

THIS FIRST AMENDMENT TO SUMMIT OFFICE LEASE (this “Amendment”) is made and entered into as of September 27, 2013, by and
between ALISO VIEJO RP-V1, LLC, a Delaware limited liability company (“Landlord”), and AVANIR PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”). 

R E C I T A L S 

A. Landlord and Tenant are parties to that certain Summit Office Lease dated as of February 1, 2011 (the “Lease”).
Pursuant to the Lease, Tenant leases certain space containing approximately 29,790 rentable square feet (26,362 usable square feet) and commonly known as Suite 200 (the “Existing Premises”) in the building located at 20 Enterprise,
Aliso Viejo, California (the “Existing Building”), as more particularly described in the Lease. 
 B. By this Amendment,
Landlord and Tenant desire to (i) expand the Existing Premises to include certain space in the building located at 30 Enterprise, Aliso Viejo, California and containing approximately 134,726 rentable square feet (the “Expansion
Building”), (ii) extend the Term of the Lease with respect to the Existing Premises and (iii) otherwise modify the Lease as provided herein. 

C. Unless otherwise defined herein, capitalized terms as used herein shall have the same meanings as given thereto in the Lease. 

NOW, THEREFORE, in consideration of the foregoing recitals and the mutual covenants contained herein, and for other good and valuable
consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto agree as follows: 
 A G
R E E M E N T 
 1. Expansion of the Premises. That certain space within the
Expansion Building consisting of approximately 8,079 rentable square feet (7,120 usable square feet) and commonly known as Suite 120, as outlined on the floor plan attached hereto as Exhibit A, is referred to herein as the
“Expansion Premises.” Commencing upon the date that the Expansion Premises are “Ready for Occupancy” (the “Expansion Commencement Date”), as determined in accordance with Section 5.1 of the Work
Letter attached hereto as Exhibit B (the “Work Letter”), the Existing Premises shall be increased to include the Expansion Premises. The Expansion Commencement Date is estimated to be January 1, 2014. Following the
occurrence of the actual Expansion Commencement Date. Landlord may deliver to Tenant a Commencement Letter in the form attached to the Lease as Exhibit C, which Tenant shall execute and return to Landlord within ten (10) Business Days of
Tenant’s receipt thereof. Such addition of the Expansion Premises to the Existing Premises shall, effective as of the Expansion Commencement Date, increase the number of rentable square feet leased by Tenant in the Building to a total of 37,869
rentable square feet (33,482 usable square feet). Effective as of the Expansion Commencement Date, all references in the Lease, as amended hereby (the “Amended Lease”), to the “Premises” shall mean and refer to the
Existing Premises as expanded by the Expansion Premises. 
 2. Expansion Term. The term for Tenant’s leasing of the Expansion
Premises shall be fifty-two (52) months (the “Expansion Term”). The Expansion Term shall commence on the Expansion Commencement Date and, unless terminated early in accordance with the Amended Lease, end fifty-two
(52) months thereafter (the “Expansion Expiration Date”). Effective as of the date hereof, all references in the Amended Lease to the “Term” shall be deemed to include the Expansion Term. 

3. Extension of Term for Existing Premises. Notwithstanding anything to the contrary in the Lease, the Term for Tenant’s leasing
of the Existing Premises shall be extended, unless earlier terminated in accordance with the Amended Lease, until the Expansion Expiration 

 
Date, such that Tenant’s leasing of the entire Premises (i.e., Existing Premises and Expansion Premises) expires coterminously. Effective as of the date hereof, all references in the Lease
to the “Termination Date” shall be deemed to mean the Expansion Expiration Date. Notwithstanding the extension of the Term hereby, Tenant shall retain the Renewal Option pursuant to Section 3.5 of the Lease with respect to the entire
Premises. 
 4. Monthly Base Rent. 

(a) Tenant shall continue to pay all Monthly Base Rent attributable to the Existing Premises in accordance with the terms of
the Lease; provided, however, that commencing on December 1, 2016 and continuing until the Expansion Expiration Date, Tenant shall pay Monthly Base Rent for the Existing Premises as follows: 

 

									
	 Period/Months
	  	Monthly Rate Per
Rentable Square Foot
for Existing Premises	 	  	Monthly Base Rent for
Existing Premises	 
	 12/1/16 – 11/30/17
	  	$	2.45	  	  	$	72,985.50	  
	 12/1/17 – Expansion Expiration Date
	  	$	2.52	  	  	$	75,070.80	  

 (b) Commencing as of the Expansion Commencement Date and continuing until the Expansion
Expiration Date, in addition to all Monthly Base Rent attributable to the Existing Premises, Tenant shall also pay Monthly Base Rent for the Expansion Premises in accordance with the terms of the Amended Lease as follows: 

 

									
	 Period/Months
	  	Monthly Rate Per
Rentable Square Foot
for Expansion Premises	 	 	Monthly Base Rent for
Expansion Premises	 
	 1 – 3
	  	 	Free	** 	 	 	Free	** 
	 4 – 12
	  	$	2.75	  	 	$	22,217.25	  
	 13 – 24
	  	$	2.83	  	 	$	22,863.57	  
	 25 – 36
	  	$	2.92	  	 	$	23,590.68	  
	 37 – 48
	  	$	3.00	  	 	$	24,237.00	  
	 49 – 52
	  	$	3.10	  	 	$	25,044.90	  

  

	**	Base Rent for the Expansion Premises shall be abated during the first (1st) through the third
(3rd) calendar months of the Expansion Term in accordance with the terms of Section 4(c) below. 

(c) Provided Tenant is not in default under the Amended Lease beyond any applicable notice and cure period, Landlord hereby
agrees to abate Tenant’s obligation to pay Base Rent for the Expansion Premises during the first (1st), second (2nd) and third (3rd) calendar months of the Expansion Term (such total amount of abated Base Rent being hereinafter referred to as the “Abated Amount”). During such abatement period, Tenant will
still be responsible for the payment of all other monetary obligations under the Amended Lease. Tenant acknowledges that any default by Tenant under the Amended Lease beyond any applicable notice and cure period will cause Landlord to incur costs
not contemplated hereunder, the exact amount of such costs being extremely difficult and impracticable to ascertain. Therefore, should Tenant at any time during the Expansion Term be in default beyond any applicable notice and cure period, then the
total unamortized sum of the Abated Amount shall become immediately due and payable by Tenant to Landlord; provided, however, Tenant acknowledges and agrees that nothing in this Section 4(c) is intended to limit any other remedies available to
Landlord at law or in equity under applicable law (including, without limitation, the remedies under Civil 

  
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Code Section 1951.2 and/or 1951.4 and any successor statutes or similar laws), in the event Tenant defaults under the Amended Lease. 

5. Tenant’s Pro Rata Share for Expansion Premises. Commencing as of the Expansion Commencement Date and continuing through the
Expansion Expiration Date, Tenant’s Pro Rata Share with respect to the Expansion Premises only (“Tenant’s Expansion Premises Pro Rata Share”) shall be 6.00%, which is the ratio that the rentable square footage of the
Expansion Premises bears to the rentable square footage of the Expansion Building. 
 6. Operating Expenses; Real Estate Taxes; Base
Year. Tenant shall not pay any Operating Expenses or Real Estate Taxes with respect to the Expansion Premises only for the first twelve (12) months of the Expansion Term. Commencing as of the one (1) year anniversary after the
Expansion Commencement Date and continuing through the Expansion Expiration Date, Tenant shall pay Tenant’s Expansion Premises Pro Rata Share of Operating Expense Excess and the Real Estate Tax Excess with respect to Operating Expenses and
Real Estate Taxes for the Expansion Building and the Project. The Base Year with respect to Operating Expenses and Real Estate Taxes for the Expansion Premises only shall be the calendar year 2014. 

7. Letter of Credit. The parties hereby acknowledge and agree that Tenant is entitled, in accordance with Section 6.5.3 of the
Lease, to reduce the face amount of the Letter of Credit previously provided by Tenant to Landlord to Three Hundred Seventy-Five Thousand Dollars ($375,000.00). The parties also hereby agree that the face amount of the Letter of Credit, as reduced
in accordance with Section 6.5.3 of the Lease, shall be increased by an amount of Two Hundred Fifty Thousand Dollars ($250,000.00) as additional collateral for the full performance by Tenant of its obligations under the Amended Lease, bringing
the total face amount of the Letter of Credit to Six Hundred Twenty-Five Thousand Dollars ($625,000.00). Therefore, concurrently with Tenant’s execution of this Amendment, Tenant shall cause the Letter of Credit to be renewed or extended, or a
substitute Letter of Credit be provided, as applicable, such that (i) the face amount of said Letter of Credit shall decrease to Six Hundred Twenty-Five Thousand Dollars ($625,000.00) and (ii) said Letter of Credit shall remain in place
and shall expire no earlier than sixty (60) days after the Expansion Expiration Date (or sixty (60) days after such later expiration date, if the Term of the Lease is further extended pursuant to the exercise of any renewal option).
Accordingly, effective as of the date hereof, all references in the Amended Lease to (i) the “LC 1 Credit Amount” shall be deemed to be Six Hundred Twenty-Five Thousand Dollars ($625,000.00) and (ii) the “LC 2 Credit
Amount” shall be deemed to be Three Hundred Twenty-Seven Thousand Eight Hundred Seventy-Five and 92/100 Dollars ($327,875.92). 
 8.
Condition of Premises. 
 (a) Existing Premises. Tenant is currently in possession of the Existing Premises and
acknowledges that Landlord shall not be obligated to refurbish or improve the Existing Premises or to otherwise fund improvements for the Existing Premises in any manner whatsoever. 

(b) Expansion Premises. Tenant acknowledges that, except as expressly set forth in this Amendment, neither Landlord nor
any agent of Landlord has made any representation or warranty with respect to the Expansion Premises or its condition, or with respect to the suitability thereof for the conduct of Tenant’s business. Landlord shall deliver the Expansion
Premises to Tenant with (i) the Tenant Improvements substantially completed (as defined in the Work Letter) in accordance with the terms and conditions of the Work Letter and (ii) exterior landscaping improvements in accordance with the
Project’s landscaping standards and as set forth in the landscaping plan attached hereto as Exhibit C and made a part hereof (collectively, the “Landlord Work”). Except for Landlord’s obligation to perform the
Landlord Work, Tenant hereby acknowledges that, except as expressly set forth in this Amendment, Landlord shall not be obligated to refurbish or improve the Expansion Premises or to otherwise fund improvements for the Expansion Premises in any
manner whatsoever, and Tenant hereby agrees that Tenant shall accept the Expansion Premises in its “AS-IS” condition on delivery by Landlord. 

9. Early Entry. Landlord shall allow Tenant to enter the Expansion Premises approximately fourteen (14) Business Days prior to the
date upon which the Expansion Premises is deemed “substantially complete” for the sole purpose of installing furniture, telecommunications systems, data cabling, equipment or other personal property (the

  
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“Preparation Work”). Provided that (i) Tenant has provided prior written notice to Landlord of its intention to enter the Expansion Premises under this Section 9;
(ii) Tenant delivers to Landlord the insurance certificates required under Section 14 of the Lease; and (iii) such early entry is for the sole purpose of performing the Preparation Work, Tenant shall not be required to pay Rent with
respect to the Expansion Premises only during such fourteen (14) Business Day early occupancy period, but shall otherwise be subject to all of the terms and conditions of the Amended Lease. Any such early entry by Tenant shall not interfere
with the completion of the Tenant Improvements or the improvement work of any other tenants in the Expansion Building and Tenant shall use its good faith, reasonable efforts to coordinate its early entry so as not to interfere with the completion of
the Tenant Improvements. Notwithstanding the foregoing, Landlord may terminate Tenant’s early right of entry with prior written notice at any time without any liability to Tenant for any loss or damage incurred by Tenant as a result thereof, in
the event Landlord reasonably determines that Tenant’s presence is interfering with the completion of the Tenant Improvements or the improvement work of any other tenants in the Expansion Building; provided that in the event Landlord terminates
Tenant’s early right of entry in accordance with this Section 9, the Expansion Commencement Date shall be extended such that Tenant is afforded a total of 14 Business Days (but in no event more than 14 Business Days) early access to the
Expansion Premises. 
 10. Right of First Offer. 

(a) Grant of Option; Conditions. Tenant shall have an ongoing right of first offer (the “Right of First
Offer”) with respect to adjacent, contiguous space to the Expansion Premises on the ground floor of the Expansion Building (the “ROFO Space”). Tenant’s Right of First Offer shall be exercised as follows: at any time
after Landlord has determined that the existing tenant in any ROFO Space will not extend or renew the term of its lease for such ROFO Space (but prior to leasing such ROFO Space to a party other than the existing tenant), Landlord shall deliver
written notice to Tenant (the “ROFO Notice”) of the terms under which Landlord is prepared to lease the ROFO Space to Tenant for the remainder of the Term, which terms shall reflect the Prevailing Market (hereinafter defined) rate
for such ROFO Space as reasonably determined by Landlord. Tenant may lease such ROFO Space in its entirety only, under such terms, by delivering written notice of exercise to Landlord (the “Notice of Exercise”) within ten
(10) Business Days after the date of the ROFO Notice, except that Tenant shall have no such Right of First Offer and Landlord need not provide Tenant with a ROFO Notice, if: 

i. Tenant is in default under the Lease beyond any applicable cure periods at the time that Landlord would otherwise deliver
the ROFO Notice; or 
 ii. the Expansion Premises, or any portion thereof, is sublet (other than pursuant to a Permitted
Transfer) at the time Landlord would otherwise deliver the ROFO Notice; or 
 iii. the Lease has been assigned (other than
pursuant to a Permitted Transfer) prior to the date Landlord would otherwise deliver the ROFO Notice; or 
 iv. Tenant is not
occupying the Expansion Premises on the date Landlord would otherwise deliver the ROFO Notice (provided, however, that the Right of First Offer shall be effective upon the mutual execution of this Amendment notwithstanding that Tenant will not yet
have taken initial occupancy of the Expansion Premises); or 
 v. Tenant does not intend to use the ROFO Space for
Tenant’s exclusive use during the Term; or 
 vi. the existing tenant in the ROFO Space is interested in extending or
renewing its lease for the ROFO Space or entering into a new lease for such ROFO Space. 
 (b) Terms for ROFO Space.

 i. The term for the ROFO Space shall commence upon the commencement date stated in the ROFO Notice and thereupon such ROFO
Space shall be considered a part of the Premises, provided that all of the terms stated in 

  
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the ROFO Notice shall govern Tenant’s leasing of the ROFO Space and only to the extent that they do not conflict with the ROFO Notice, the terms and conditions of the Amended Lease shall
apply to the ROFO Space. 
 ii. Tenant shall pay Base Rent and Additional Rent for the ROFO Space in accordance with the
terms and conditions of the ROFO Notice, which terms and conditions shall reflect the Prevailing Market rate for the ROFO Space as determined in Landlord’s reasonable judgment. 

iii. The ROFO Space (including improvements and personalty, if any) shall be accepted by Tenant in its condition and as-built
configuration existing on the earlier of the date Tenant takes possession of the ROFO Space or as of the date the term for such ROFO Space commences, unless the ROFO Notice specifies any work to be performed by Landlord in the ROFO Space, in which
case Landlord shall perform such work in the ROFO Space. If Landlord is delayed delivering possession of the ROFO Space due to the holdover or unlawful possession of such space by any party, Landlord shall use reasonable efforts to obtain possession
of the space, and the commencement of the term for the ROFO Space shall be postponed until the date Landlord delivers possession of the ROFO Space to Tenant free from occupancy by any party. 

(c) Termination of Right of First Offer. The rights of Tenant hereunder with respect to the ROFO Space shall terminate
on the earlier to occur of: (i) Tenant’s failure to exercise its Right of First Offer within the ten (10) Business Day period provided in Section 10(a) above; and (ii) the date Landlord would have provided Tenant a ROFO
Notice if Tenant had not been in violation of one or more of the conditions set forth in Section 10(a) above. 
 (d)
Offering Amendment. If Tenant exercises its Right of First Offer, Landlord shall prepare an amendment (the “Offering Amendment”) adding the ROFO Space to the Premises on the terms set forth in the ROFO Notice and reflecting
the changes in the Base Rent, rentable square footage of the Premises, Tenant’s Pro Rata Share and other appropriate terms. A copy of the Offering Amendment shall be sent to Tenant within a reasonable time after Landlord’s receipt of the
Notice of Exercise executed by Tenant, and Tenant shall execute and return the Offering Amendment to Landlord within thirty (30) days thereafter, but an otherwise valid exercise of the Right of First Offer shall be fully effective whether or
not the Offering Amendment is executed. 
 (e) Definition of Prevailing Market. For purposes of this Right of First
Offer provision, “Prevailing Market” shall mean the annual rental rate per square foot for space comparable to the ROFO Space in the Expansion Building under leases and renewal and expansion amendments being entered into at or about the
time that Prevailing Market is being determined, giving appropriate consideration to tenant concessions, brokerage commissions, tenant improvement allowances, existing improvements in the space in question, and the method of allocating operating
expenses and taxes. Notwithstanding the foregoing, space leased under any of the following circumstances shall not be considered to be comparable for purposes hereof: (i) the lease term is for less than the lease term of the ROFO Space,
(ii) the space is encumbered by the option rights of another tenant, or (iii) the space has a lack of windows and/or an awkward or unusual shape or configuration. The foregoing is not intended to be an exclusive list of space that will not
be considered to be comparable. 
 (f) Subordination. Notwithstanding anything herein to the contrary, Tenant’s
Right of First Offer is subject and subordinate to the expansion rights (whether such rights are designated as a right of first offer, right of first refusal, expansion option or otherwise) of any tenant of the Building or Project existing prior to
the date hereof. 
 11. Parking. Commencing on the Expansion Commencement Date, in addition to Tenant’s existing parking rights
under the Lease, Tenant shall be entitled to rent up to eight (8) labeled reserved parking spaces at the prevailing rate for such spaces (as of the date hereof, the monthly rate is $60.00 per space) and otherwise in accordance with the terms of
the Lease. 
 12. Signage. Tenant shall be entitled, at Landlord’s sole cost and expense, to identification signage
(i) adjacent to the doorway providing entrance to the Expansion Premises 

  
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on the floor on which the Expansion Premises are located and (ii) on the interactive directory screen located in the lobby of the Expansion Building, subject to Landlord’s reasonable
approval, and otherwise in accordance with the terms of the Lease. In addition to the aforementioned signage, Tenant shall have the right to install one (1) sign (the “Eyebrow Sign”) in an eyebrow sign location of the Expansion
Building approved by Landlord and as depicted on the Sign Location Map and Signage Criteria attached hereto as Exhibit D and made a part hereof, provided (a) Tenant receives the approval of the City of Aliso Viejo, California to
install the Eyebrow Sign and the Eyebrow Sign is in accordance with all applicable signage codes, laws, regulations and ordinances, (b) Tenant submits to Landlord, and Landlord approves, reasonably detailed drawings of the Eyebrow Sign prior to
installing the Eyebrow Sign, (c) the type, size and style of the Eyebrow Sign shall be subject to the sign criteria applicable to the Expansion Building and as set forth in Exhibit D, and (d) Tenant shall bear the responsibility for
all costs associated with the Eyebrow Sign, including but not limited to design, government permits and approvals, construction, installation, insurance, on-going maintenance and removal and repair at the expiration of the Term. Following
installation, signs subject to this Section 12 shall become the property of Tenant. 
 13. Brokers. Each party represents and
warrants to the other that with the exception of CBRE, Inc., representing Landlord, and Newmark Grubb Night Frank, representing Tenant, no other broker, agent or finder negotiated or was instrumental in negotiating or consummating this Amendment.
Each party further agrees to defend, indemnify and hold harmless the other party from and against any claim for commission or finder’s fee by any person or entity other than the above-named brokers who claims or alleges that such other person
or entity was retained or engaged by the indemnifying party or at the request of such party in connection with this Amendment. 
 14.
California Accessibility Disclosure. For purposes of Section 1938 of the California Civil Code, Landlord hereby discloses to Tenant, and Tenant hereby acknowledges, that the Premises has not undergone inspection by a Certified Access
Specialist (CASp). In the event such an inspection is required by regulatory or governmental requirements, Landlord shall be responsible for such inspection requirements and all applicable costs, provided that any such costs shall be included in
Operating Expenses. 
 15. Notices. Section 1.1 of the Lease is hereby amended to substitute the following for Landlord’s
and Tenant’s notice addresses, respectively: 
  

	 	(a)	Landlord’s Address: 

 ALISO VIEJO RP-V1, LLC 

c/o Parker Summit V, LLC 
 20
Enterprise, Suite 305 
 Aliso Viejo, California 92656 

Attention: Principal – Leasing 
  

	 	(b)	Tenant’s Address: 

 Avanir Pharmaceuticals, Inc. 

20 Enterprise, Suite 200 
 Aliso
Viejo, California 92656 
 Attention:
                     
 With a
copy to: 
 Avanir Pharmaceuticals, Inc. 

20 Enterprise, Suite 200 
 Aliso
Viejo, California 92656 
 Attention: Vice President, Legal Affairs Dept. 

16. Tenant Representations. Each person executing this Amendment on behalf of Tenant represents and warrants to Landlord that:
(a) Tenant is properly formed and validly existing under the laws of the state in which Tenant is formed and Tenant is authorized to transact business in the state in which the Expansion Building is located; (b) Tenant has full right and
authority to enter into this Amendment and to perform all of Tenant’s obligations hereunder; 

  
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and (c) each person signing this Amendment on behalf of Tenant is duly and validly authorized to do so. 

17. No Further Modification; Counterparts. Except as set forth in this Amendment, all of the terms and provisions of the Lease shall
apply with respect to the Expansion Premises and shall remain unmodified and in full force and effect. Effective as of the date hereof, all references to the “Lease” shall refer to the Amended Lease. This Amendment may be executed in
counterparts, each of which shall be deemed an original, but such counterparts, when taken together, shall constitute one agreement. 

[REMAINDER OF PAGE INTENTIONALLY BLANK; SIGNATURES FOLLOW] 

  
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 IN WITNESS WHEREOF, this Amendment has been executed as of the day and year first above written.

  

			
	 TENANT:

	
	 AVANIR PHARMACEUTICALS, INC.,

a Delaware corporation

		
	 By:
	 	/s/ Christine G. Ocampo
	 Name:
	 	Christine Ocampo
	 Title:
	 	VP of Finance
		
	 By:
	 	/s/ Keith Katkin
	 Name:
	 	Keith Katkin
	 Title:
	 	President & CEO

  

							
	 LANDLORD:

	
	 ALISO VIEJO RP-V1, LLC,

a Delaware limited liability company

		
	 By:
	 	 Parker Summit V, LLC,
 a Delaware
limited liability company
 Its:      Member

			
		 	By:	 	/s/ Lee R. Redmond III
		 	Name:	 	Lee R. Redmond III
		 	Title:	 	Managing Member
		
	 By:
	 	Gateway Aliso Viejo, L.P.,
a California limited partnership
Its:      Managing Member
			
		 	By:	 	 RREEF America, L.L.C.,
a Delaware limited liability company

Its:      Manager

				
		 		 	By:	 	/s/ Marvin Christensen
		 		 	Name:	 	Marvin Christensen
		 		 	Title:	 	Representative

  

	*	NOTE: 

 If Tenant is a corporation incorporated in a state other than California, then
Tenant shall deliver to Landlord a certified copy of a corporate resolution in a form reasonably acceptable to Landlord authorizing the signatory(ies) to execute this Amendment. 

  
 -8- 

 EXHIBIT B 

WORK LETTER 
 This
Work Letter shall set forth the terms and conditions relating to the construction of the tenant improvements in the Expansion Premises. This Work Letter is essentially organized chronologically and addresses the issues of the construction of the
Expansion Premises, in sequence, as such issues will arise during the actual construction of the Expansion Premises. All references in this Work Letter to Articles or Sections of “this Amendment” shall mean the relevant portions of the
Amendment to which this Work Letter is attached as Exhibit B and of which this Work Letter forms a part, and all references in this Work Letter to Sections of “this Work Letter” shall mean the relevant portion of Sections 1
through 6 of this Work Letter. 
 SECTION 1 

LANDLORD’S INITIAL CONSTRUCTION IN THE EXPANSION PREMISES 

1.1 Base, Shell and Core of the Expansion Premises as Constructed by Landlord. Landlord has constructed or will construct, the base,
shell and core of the Expansion Building as generally described on Schedule 1, attached hereto (the “Base, Shell, and Core”). 

1.2 Intentionally Omitted. 

SECTION 2 
 TENANT
IMPROVEMENTS 
 2.1 Tenant Improvements; Generally. Landlord shall construct, at its sole cost and expense (except as otherwise
provided in this Work Letter) up to an amount not to exceed $391,600 (i.e., $55.00 per usable square foot of the Expansion Premises) (the “Cap”), office improvements in the Expansion Premises (the “Tenant Improvements”) that
substantially conform to the Final Space Plan (defined in Section 3.2 below) and that substantially conform to Landlord’s Standard Improvement Package (as defined in Section 2.2 below) or such other materials and finishes as agreed to
in writing by Landlord and Tenant. All of those costs and expenses incurred in connection with the construction of the Tenant Improvements in excess of the amount of the Cap shall be the responsibility of Tenant, as more particularly set forth in
this Work Letter. 
 2.2 Costs Charged Against the Cap. All of the costs related to the construction of the Tenant Improvements shall
be charged against the Cap, along with the following items and costs (collectively, the “Tenant Improvement Cap Items”): (i) payment of the fees of the “Architect” and the “Engineers,” as those terms are defined in
Section 3.1 of this Work Letter; (ii) payment of the fees incurred by, and the cost of documents and materials supplied by, Landlord and Landlord’s consultants in connection with the preparation and review of the “Construction
Drawings,” as that term is defined in Section 3.1 of this Work Letter; (iii) the cost of obtaining any and all permits for the construction of the Tenant Improvements; (iv) the cost of any changes in the Base, Shell and Core when
such changes are required by the Construction Drawings (including the cost for the electrical metering of the Expansion Premises contemplated in the Amendment); (v) the cost of any changes to the Construction Drawings or Tenant Improvements
required by all applicable building codes (the “Code”); and (vi) the “Landlord Supervision Fee”, as that term is defined in Section 4.3.1 of this Work Letter. 

2.3 Standard Tenant Improvement Package. Landlord has established specifications (the “Specifications”) for the Expansion
Building standard components to be used in the construction of the Tenant Improvements in the Expansion Premises (collectively, the “Standard Improvement Package”), which Specifications are set forth on Schedule 2, attached hereto.
The quality of Tenant Improvements shall be equal to or of greater quality than the quality of the Specifications. 
 2.4 No Removable
Items. Tenant shall not be required to remove any Tenant Improvements from the Expansion Premises at the expiration or earlier termination of the Lease. 

SECTION 3 
 CONSTRUCTION
DRAWINGS 
 3.1 Selection of Architect/Construction Drawings. The architect/space planner designated by Landlord and Tenant,
Shlemmer Algaze Associates (the “Architect”), shall prepare the “Construction Drawings,” as that term is defined in this Section 3.1. The engineering consultants designated by Landlord (the “Engineers”) shall
prepare all plans and engineering working drawings relating to the structural, mechanical, electrical, plumbing, HVAC, life-safety, and sprinkler work of the Tenant Improvements. The plans and drawings to be prepared by the Architect and the
Engineers hereunder shall 

  
 EXHIBIT B 

-1- 

 
be known collectively as the “Construction Drawings”, and shall be based upon the Final Space Plan (defined below). All Construction Drawings shall comply with the drawing format and
specifications as determined by Landlord, and shall be subject to Landlord’s approval. The Architect shall verify, in the field, the dimensions and conditions as shown on the relevant portions of the base Expansion Building plans, and Landlord
shall have no responsibility in connection therewith. Landlord’s review of the Construction Drawings as set forth in this Section 3, shall be for its sole purpose and shall not imply Landlord’s review of the same, or obligate Landlord
to review the same, for quality, design, Code compliance or other like matters. Accordingly, notwithstanding that any Construction Drawings are reviewed by Landlord or its space planner, architect, engineers and consultants, and notwithstanding any
advice or assistance which may be rendered to Tenant by Landlord or Landlord’s space planner, architect, engineers, and consultants, neither Landlord nor Tenant shall have any liability to each other whatsoever in connection therewith and shall
not be responsible for any omissions or errors contained in the Construction Drawings. 
 3.2 Final Space Plan. Landlord and Tenant
have approved the final space plan for the Tenant Improvements to be constructed in the Expansion Premises (collectively, the “Final Space Plan”), which is attached hereto as Schedule 4. 

3.3 Final Working Drawings; Final Pricing Plan. The Architect and the Engineers shall complete the architectural and engineering
drawings based upon the Final Space Plan for the Premises, and the final architectural working drawings in a form which is complete to allow subcontractors to bid on the work and to obtain all applicable permits (collectively, the “Final
Working Drawings”) and shall submit the same to Landlord for Landlord’s approval, and Landlord shall, in turn, submit the same to Tenant for Tenant’s approval, together with a “Final Pricing Plan,” which approval shall be
given on or before the date set forth on Schedule 3. Tenant may work with the Architect, Landlord and the Contractor (defined below) to value engineer the Final Working Drawings for the purpose of reducing the cost of the Tenant Improvements,
but under no circumstance shall the Tenant Improvements be rebid as a result of any revisions to the Final Working Drawings; provided, however, so long as Landlord is using commercially reasonable efforts to respond to any requests and comments made
to the Final Working Drawings and Final Pricing Plan by Tenant, in the event that Landlord and Tenant have not agreed upon the Final Working Drawings and Final Pricing Plan by November 1, 2013 (the date of which shall be extended in the event
such extension is requested by the Architect for its business purposes), each day thereafter may be deemed a “Tenant Delay” if delayed by Tenant until the parties have agreed upon the Final Working Drawings and Final Pricing Plan.
Tenant’s failure to provide any comments or disapprovals within such time shall be deemed Tenant’s approval thereof. If Tenant reasonably disapproves the Final Pricing Plan, Landlord and Tenant shall negotiate in good faith to reach
agreement on the items contained in the Final Pricing Plan, provided that Landlord shall not be obligated to approve any changes proposed by Tenant to the Final Pricing Plan to the extent the proposed changes are inconsistent with the Standard
Improvement Package or if the quality of the Tenant Improvements will not be equal to or of greater quality than the Specifications. Upon receipt of the approved Final Pricing Plan by Landlord, Landlord shall be released by Tenant to purchase the
items set forth in the Final Pricing Plan and to commence the construction relating to such items. 
 3.4 Permits; Excess Costs. The
Final Working Drawings shall be approved by Landlord and Tenant (the “Approved Working Drawings”) prior to the commencement of the construction of the Tenant Improvements. Landlord shall submit the Approved Working Drawings to the
appropriate municipal authorities for all applicable building permits necessary to allow “Contractor,” as that term is defined in Section 4.1, below, to commence and fully complete the construction of the Tenant Improvements (the
“Permits”), and, in connection therewith, Landlord shall coordinate with the Architect and Contractor in all phases of the permitting process and shall monitor all plan check numbers and dates of submittal in order to obtain the Permits.
No changes, modifications or alterations in the Approved Working Drawings may be made without the prior written consent of Landlord and Tenant, which shall not be unreasonably withheld or delayed. Tenant may request changes to the Approved Working
Drawings provided that (a) the changes shall not be of a lesser quality than Landlord’s standard Specifications (as described in Section 2.2 above) for tenant improvements for the Expansion Building, as the same may be changed from
time to time by Landlord; (b) the changes conform to applicable governmental regulations and necessary governmental permits and approvals can be secured; (c) the changes do not require building service beyond the levels normally provided
to other tenants in the Expansion Building; (d) the changes do not have any adverse affect on the structural integrity or systems of the Expansion Building; (e) the changes will not, in Landlord’s opinion, unreasonably delay
construction of the Tenant Improvements; and (f) Landlord has determined in its sole discretion that the changes are of a nature and quality consistent with the overall objectives of Landlord for the Expansion Building. To the extent any such
change results in a delay of completion of construction of the Tenant Improvements, then such delay shall constitute a delay caused by Tenant as described below. To the extent any such change approved by Landlord results in the total cost of the
Tenant Improvements to exceed the amount of the Cap, Tenant shall deliver to Landlord, in good and sufficient funds, fifty percent (50%) of the amount of such excess costs within five (5) Business Days following Landlord’s written
request. As described above in this Work Letter, Tenant shall also be responsible for all of those costs and expenses relating to the construction of the Tenant Improvements (including the Tenant Improvement

  
 EXHIBIT B 

-2- 

 
Cap Items) in excess of the amount of the Cap, and for purposes of this Work Letter, such costs and expenses in excess of the Cap amount and said costs described above relating to changes in the
Approved Working Drawings which result in the total cost of the Tenant Improvements exceeding the amount of the Cap shall be collectively referred to as the “Excess Cost Amount”. Fifty percent (50%) of the Excess Cost Amount shall be
paid to Landlord within five (5) Business Days of the parties’ approval of the Final Pricing Plan, or within five (5) Business Days of written request with respect to any change to the Approved Working Drawings, as applicable.
Landlord shall have no obligation to commence construction of the Tenant Improvements until Tenant pays to Landlord such portion of the Excess Cost Amount. Upon completion of the Tenant Improvements, Tenant shall deliver the balance of the Excess
Cost Amount to Landlord or Landlord shall promptly thereafter refund any unused amount to Tenant. Any costs associated with final inspection or regulatory activities prior to Tenant occupancy shall be the responsibility of the Landlord, but shall be
charged against the Cap as a Tenant Improvement Cap Item. 
 3.5 Time Deadlines. Tenant and Landlord shall use their respective best,
good faith efforts and all due diligence to cooperate with the Architect and the Engineers to complete all phases of the Construction Drawings and the permitting process and to receive the permits as soon as possible after the execution of the
Amendment. Tenant shall meet with Landlord on a scheduled basis at mutually agreeable times, to discuss mutual progress in connection with the same. The applicable dates for approval of items, plans and drawings as described in this Section 3,
Section 4 below, and in this Work Letter are set forth and further elaborated upon in Schedule 3 (the “Time Deadlines”), attached hereto. Tenant agrees to comply with the Time Deadlines. 

SECTION 4 
 CONSTRUCTION
OF THE TENANT IMPROVEMENTS 
 4.1 Contractor. A contractor designated by Landlord (the “Contractor”) shall construct
the Tenant Improvements. No later than three (3) Business Days prior to Landlord’s retention of the Contractor, Landlord shall provide the name of the Contractor to Tenant to provide Tenant with three (3) Business Days to confirm that
the Contractor is not a person excluded or debarred or subject to exclusion or debarment under 21 U.S.C. §335(a) or subject to any restrictions or sanctions by the FDA, Office of Inspector General, or any other governmental or regulatory
authority or professional body (a “Debarred Person”). In the event that Tenant informs Landlord within such three (3) Business Day period that Contractor is a Debarred Person and provides Landlord with reasonable evidence of same,
Landlord shall designate another contractor and the parties shall repeat the procedure set forth in the immediately preceding sentence until Landlord has designated a Contractor that Tenant has confirmed (or deemed confirmed) is not a Debarred
Person. Tenant’s failure to notify Landlord within such three (3) Business Day period shall be deemed Tenant’s confirmation that such contractor is not a Debarred Person. Tenant hereby acknowledges that (a) it is relying solely
upon its own investigations with respect to the status of the Contractor or any other contractor as a Debarred Person, (b) Landlord makes no representation, warranty or covenant in any way whatsoever with respect to the status of the Contractor
or any other contractor as a Debarred Person, and (c) Landlord shall have no liability whatsoever with respect to same. 
 4.2
Landlord’s Payment for Tenant Improvements. Landlord shall be obligated to pay for all costs for the design, permitting and construction of the Tenant Improvements up to an amount not to exceed the Cap. 

4.3 Construction of Tenant Improvements by Contractor under the Supervision of Landlord. 

4.3.1 Landlord’s Retention of Contractor. Landlord shall independently retain the Contractor to construct the
Tenant Improvements in accordance with the Approved Working Drawings and Landlord shall supervise the construction by the Contractor. Tenant shall pay a construction supervision and management fee (the “Landlord Supervision Fee”) to
Landlord in an amount equal to three percent (3%) of the total costs related to the construction of the Tenant Improvements; provided, however, that Tenant shall only pay a one and a half percent (1.5%) Landlord Supervision Fee with
respect to the Excess Cost Amount, if any. Landlord shall bear all responsibility and liability associated with securing applicable construction lien releases from all applicable third parties, including construction Contractor(s). 

4.3.2 Contractor’s Warranties and Guaranties. Landlord shall obtain from the Contractor a one (1) year
warranty (commencing on the Commencement Date) that the Tenant Improvements have been completed substantially in accordance with the Approved Working Drawings and are free from construction defects in materials and workmanship. If (i) it is
determined that the Tenant Improvements have not been completed substantially in accordance with this Work Letter and the Approved Working Drawings and/or contain any such construction defects, (ii) such failure and/or construction defects do
not arise out of any act, omission or negligence of Tenant, its agents or employees, and (iii) Tenant notifies Landlord of such applicable failure and/or construction defects within one hundred eighty (180) days after the

  
 EXHIBIT B 

-3- 

 
Expansion Commencement Date, then Landlord shall, at no cost to Tenant, correct such construction defect. Following the expiration of said 180-day period, Landlord shall assign to Tenant all
warranties and guaranties by Contractor relating to the Tenant Improvements, and Tenant shall be deemed to have waived all claims against Landlord relating to, or arising out of the construction of, the Tenant Improvements. Notwithstanding the
foregoing and to the extent necessary, Landlord shall use commercially reasonable efforts following the expiration of said 180-day period, at no out-of-pocket cost to Landlord, to assist Tenant in enforcing such warranties and guaranties by
Contractor relating to the Tenant Improvements. 
 SECTION 5 

COMPLETION OF THE TENANT IMPROVEMENTS; 

EXPANSION COMMENCEMENT DATE 

5.1 Ready for Occupancy. The Expansion Premises shall be deemed “Ready for Occupancy” upon the earlier of (a) the date
upon which Tenant takes possession of the Expansion Premises and commences business operations from the Expansion Premises or (b) the date of substantial completion of the Expansion Premises. For purposes of the Amendment, “substantial
completion” of the Expansion Premises shall occur upon (i) the completion of construction of the Tenant Improvements in the Expansion Premises pursuant to this Work Letter and the Approved Working Drawings, with the exception of any minor
punch list items and any tenant fixtures, work-stations, built-in furniture, or equipment to be installed by Tenant or under the supervision of the Contractor, and (ii) the date a certificate of occupancy or other required equivalent approval
from the local governmental authority is issued permitting occupancy of the Expansion Premises (such as sign off on the building inspection cards). 

5.2 Delay of the Substantial Completion of the Expansion Premises. Except as provided in this Section 5.2, the Expansion
Commencement Date shall occur as set forth in the Amendment and Section 5.1, above. If there shall be a delay or there are delays in the substantial completion of the Expansion Premises or in the occurrence of any of the other conditions
precedent to the Expansion Commencement Date, as set forth in the Amendment, as a direct, indirect, partial, or total result of (each, a “Tenant Delay”): 

5.2.1 Tenant’s failure to comply with the Time Deadlines (subject to force majeure delays); 

5.2.2 Tenant’s failure to timely approve any matter requiring Tenant’s approval (provided Tenant receives all reasonable information
on a timely basis to make such determination), including, without limitation, the parties failure to approve the Final Working Drawings and Final Pricing Plan by November 1, 2013 as set forth in Section 3.3 above; 

5.2.3 A material breach by Tenant of the terms of this Work Letter or the Amended Lease; 

5.2.4 Tenant’s request for material changes in the Approved Working Drawings (which actually delays substantial completion); 

5.2.5 Tenant’s requirement for materials, components, finishes or improvements which are not available in a commercially reasonable time
given the anticipated date of substantial completion of the Expansion Premises, as set forth in the Amendment, or which are different from, or not included in, the Standard Improvement Package, provided that Landlord has informed Tenant in writing
of such lead time items prior to approval of the Approved Working Drawings; 
 5.2.6 Changes to the Base, Shell and Core required by the
Approved Working Drawings; or 
 5.2.7 Any other acts or omissions of Tenant, or its agents, or employees of which Tenant receives prompt
notice of the occurrence thereof from Landlord; 
 then, notwithstanding anything to the contrary set forth in the Amendment or this Work Letter and
regardless of the actual date of the substantial completion of the Expansion Premises, the Expansion Commencement Date shall be deemed to be the date the Expansion Commencement Date would have occurred if no Tenant delay or delays, as set forth
above, had occurred; provided that any delays identified above are not due to the acts, delays or omissions of Landlord. 

  
 EXHIBIT B 

-4- 

 SECTION 6 

MISCELLANEOUS 
 6.1
Tenant’s Early Entry Prior to Substantial Completion. Subject to the terms of Section 8 of the Amendment, provided that Tenant and its agents do not interfere with the Contractor’s work in the Expansion Building and the
Expansion Premises, Contractor shall allow Tenant access to the Expansion Premises approximately fourteen (14) Business Days prior to the substantial completion of the Expansion Premises for the purpose of Tenant installing overstandard
equipment or fixtures (including Tenant’s data and telephone equipment) in the Expansion Premises. Prior to Tenant’s entry into the Expansion Premises as permitted by the terms of this Section 6.1, Tenant shall submit a schedule to
Landlord and the Contractor, for their approval, which schedule shall detail the timing and purpose of Tenant’s entry. Tenant shall hold Landlord harmless from and indemnify, protect and defend Landlord against any loss or damage to the
Expansion Building or Expansion Premises and against injury to any persons caused by Tenant’s actions pursuant to this Section 6.1. 

6.2 Freight Elevators. Landlord shall, consistent with its obligations to other tenants of the Expansion Building, make the freight
elevator reasonably available to Tenant in connection with initial decorating, furnishing and moving into the Expansion Premises. 
 6.3
Tenant’s Representative. Tenant has designated Mike Cruse as its sole representative with respect to the matters set forth in this Work Letter, who, until further notice to Landlord, shall have full authority and responsibility to act on
behalf of the Tenant as required in this Work Letter. 
 6.4 Landlord’s Representative. Landlord has designated Matt Jepsen as
its sole representatives with respect to the matters set forth in this Work Letter, who, until further notice to Tenant, shall have full authority and responsibility to act on behalf of the Landlord as required in this Work Letter. 

6.5 Tenant’s Agents. All subcontractors, laborers, materialmen, and suppliers retained directly by Tenant shall all be union labor
in compliance with the then existing master labor agreements. 
 6.6 Time of the Essence in This Work Letter. Unless otherwise
indicated, all references herein to a “number of days” shall mean and refer to calendar days. In all instances where Tenant is required to approve or deliver an item, if no written notice of approval is given or the item is not delivered
within the stated time period, at Landlord’s sole option, at the end of such period the item shall automatically be deemed approved or delivered by Tenant and the next succeeding time period shall commence. 

6.7 Tenant’s Lease Default. Notwithstanding any provision to the contrary contained in the Amended Lease or this Work Letter, if
an event of default as described in the Amended Lease, or a default by Tenant under this Work Letter, has occurred at any time on or before the substantial completion of the Expansion Premises, then (i) in addition to all other rights and
remedies granted to Landlord pursuant to the Amended Lease, Landlord shall have the right to cause the Contractor to cease the construction of the Expansion Premises (in which case, Tenant shall be responsible for any delay in the substantial
completion of the Expansion Premises caused by such work stoppage as set forth in Section 5 of this Work Letter), and (ii) all other obligations of Landlord under the terms of this Work Letter shall be forgiven until such time as such
default is cured pursuant to the terms of the Amended Lease. 
 [SIGNATURE PAGE FOLLOWS] 

  
 EXHIBIT B 

-5- 

 Landlord and Tenant have executed this Work Letter as of the day and year first above written.

  

							
	LANDLORD:
	
	 ALISO VIEJO RP-V1, LLC,
 a Delaware
limited liability company

		
	By:	 	 Parker Summit V, LLC, a
 Delaware
limited liability company
 Its:      Member

			
		 	By:	 	 
		 	Name:	 	 
		 	Title:	 	 
		
	By:	 	Gateway Aliso Viejo, L.P.,
a California limited partnership
Its:      Managing Member
			
		 	By:	 	 RREEF America, L.L.C.,
a Delaware limited liability company

Its:      Manager

				
		 		 	By:	 	 
		 		 	Name:	 	 
		 		 	Title:	 	 

  

			
	TENANT:
	
	 AVANIR PHARMACEUTICALS, INC.,
 a
Delaware corporation

		
	By:	 	 
	Name:	 	 
	Title:	 	 
		
	By:	 	 
	Name:	 	 
	Title:	 	 

  

	*	NOTE: 

 If Tenant is a corporation incorporated in a state other than California, then
Tenant shall deliver to Landlord a certified copy of a corporate resolution in a form reasonably acceptable to Landlord authorizing the signatory(ies) to execute this Work Letter. 

  
 EXHIBIT B 

-6- 

 SCHEDULE 1 

SUMMIT PHASE V 

BASE, SHELL AND CORE DESCRIPTION 
  

			
		
	Project Description	  	1. 4-Story Office Building with 35,850 sq. ft. floor plates
		
	Structure	  	2. Floor to floor height of 13’-6” typical, 15’-0” first floor.
		
		  	3. Spread footings with grade beams at moment frame perimeter.
		
		  	4. Structural steel building with seismic moment frame.
		
	Floor	  	5. Lightweight concrete on all elevated floors.
		
	Exterior	  	6. Smooth plaster exterior skin with storefront/curtain with high-efficiency double-pane window system.
		
	Interior Finish	  	7. Ground floor public lobby complete.
		
		  	8. Finished men’s and women’s restrooms on all floors with ceramic tile floors and walls and painted gypsum board ceiling.
		
	Vertical	  	9. Two (2) Otis Gen-2 traction elevators with custom upgraded Movement cabs.
		
	Mechanical	  	10. Efficient York 60 and 70-ton rooftop package units with variable frequency drives (VFD). Master controlled energy management system with Alerton direct-digital controls (DDC).
		
	Fire Safety	  	11. Fire Sprinklers distributed with temporary heads and shields at a rate of 1/150 sq. ft.
		
	Electrical	  	12. Main switchgear 277/480 volt, 30 Enterprise—3,000 amps, 30 Enterprise – 4,000 amps main service. Receptacle loads are designed at 7 watts per square foot, lighting loads at 2 watts per square foot.

  
 SCHEDULE 1 

-1- 

 SCHEDULE 2 

BUILDING STANDARD TENANT IMPROVEMENT SPECIFICATIONS 

SUMMIT PHASE V – 20 & 30 ENTERPRISE 
  

	1)	PARTITIONS 

  

	 	a)	DEMISING PARTITION 

  

	 	i)	3 5/8” x 20 gauge metal studs at 24” on center (unless floor structure or roof structure is higher than 19’-0” A.F.F.). 20 gauge is permitted if structure above is below 13’-6” A.F.F.

  

	 	ii)	5/8” type “X” gypsum board, one layer each side of studs. 

  

	 	iii)	Full height partition from floor slab to bottom of structural slab. 

  

	 	iv)	Partition taped smooth and sanded to receive paint or scheduled finish below ceiling line. 

  

	 	v)	Owens corning “Noise Barrier”, 2  1⁄2”, R-11 batt insulation. 

 

	 	vi)	Stagger and acoustical caulk around electrical outlet and other boxes; caulk around conduit and other through wall penetrations. Caulk entire perimeter of wall at floor, exterior wall, structure and between
“L” metal finished gypsum board and intersecting wall. 

  

	 	vii)	Secure top channel and bottom with  1⁄4” shot pins at 4’-0” o.c. and 6” from corner. 

 

	 	viii)	Continuous corner beads with neoprene gasket at exterior glazing mullion. 

  

	 	ix)	All exterior corners with corner beads, all exposed edges finished with metal trim. 

  

	 	b)	INTERIOR PARTITION 

  

	 	i)	3 5/8” x 25 gauge metal studs at 24” on center with seismic bracing per code, U.N.O. 

  

	 	ii)	5/8” type “X” gypsum board, one layer each side of studs. 

  

	 	iii)	Partition taped smooth and sanded to receive paint or wall covering. 

  

	 	iv)	Height: from floor to underside of ceiling to be 9’-0” A.F.F.; 1st Floor 10’–6” A.F.F. 

  

	 	v)	Continuous corner beads with neoprene gasket at exterior glazing mullion. 

  

	 	vi)	Exterior corners with corner beads, exposed edges finished with metal trim. 

  

	 	vii)	“L” metal of partition terminates at ceiling. 

  

	 	c)	PERIMETER DRYWALL & COLUMN FURRING 

  

	 	i)	Perimeter of exterior wall to receive 3 5/8” metal studs at 24” o.c. with 5/8” type “X” gypsum board as required by current Title 24 guidelines; taped smooth and sanded to receive paint or
scheduled finish. 

  

	 	ii)	Provide or continue wall insulation to comply with the Title 24 energy code. 

  

	 	iii)	Interior structural columns to receive 3 5/8” metal studs at 24” o.c. with 5/8” type “X” gypsum board below the ceiling line or as required by current Title 24 guidelines; taped smooth and
sanded to receive paint or scheduled finish. 

  

	2)	DOOR ASSEMBLY 

  

	 	a)	CORRIDOR ENTRY DOOR ASSEMBLY 

  

	 	i)	Single door – 3’-0” x 8’-0” x 1  3⁄4” solid core wood, flush AWI premium grade plain sliced cherry
with matching hardwood stiles. 

  

	 	ii)	Double door—6’-0” x 8’-0” x 1  3⁄4” solid core, flush AWI premium grade plain sliced cherry with
matching hardwood stiles . 

  

	 	iii)	Finish—factory applied transparent or opaque finish to match Architect’s sample. 

  

	 	iv)	Rating – not rated. 

  

	 	v)	Frame—3’-0” x 8’-0”, brushed aluminum doorframe by “Western Integrated” 

  

	 	vi)	Lockset: lever hardware by “Schlage” L9453-17 mortise lockset, (6) pin “Everest” C123 keyway. Finish: 626 Satin Chrome. 

 

	 	vii) (2) 	pair Butt hinges: 4  1⁄2” x 4
 1⁄2” “Hager” BB-1279 (“Stanley”, “Soss”, “McKinney” are acceptable alternates), finish to match lever sets.

  

	 	viii)	Door Closer: “Norton” #8501 parallel arm, #689 aluminum finish. 

  

	 	ix)	Door Stop: Quality #331 floor stop, finish to match lever. 

  

	 	b)	INTERIOR DOORS 

  

	 	i)	Single door—3’-0” x 8’-0” x 1  3⁄4” solid core, flush AWI premium grade plain sliced cherry with
matching hardwood stiles. 

  

	 	ii)	Double door—6’-0” x 8’-0” x 1  3⁄4” solid core, flush AWI premium grade plain sliced cherry with
matching hardwood stiles. 

  

	 	iii)	Finish—factory applied transparent or opaque finish to match Architect’s sample. 

  

	 	iv)	Frame—3’-0” x 8’-0” x 3  3⁄4”, “Western Integrated”, brushed aluminum. 

 

	 	v)	Lockset—lever hardware by Schlage D Series “Sparta” cylindrical latch set/lockset, lockset to be 6 pin Everest C123 Keyway. Finish: 626 Satin Chrome. 

  
 SCHEDULE 2 

-1- 

 vi) (2)  pair Butt hinges: 4
 1⁄2” x 4  1⁄2” Hager 1279. 

vii) Door Stop: Quality #331 floor stop, finish to match lever. 

 

	3)	BUILT-IN MILLWORK 

  

	 	a)	Millwork cabinets to be W.I.C. custom standard flush overlay construction with 3  1⁄2” wire pulls; Finish: Satin Chrome.

  

	 	b)	Plastic Laminate Exterior use: Nevamar, Wilsonart, or Formica. 

  

	 	c)	Korton/Melamine Interiors use: white or black. 

  

	4)	ACOUSTIC CEILING SYSTEM 

  

	 	a)	Donn Fineline DXF Narrow 9/16”, face with  1⁄4” reveal, intermediate duty with white recess throughout tenant premises.

  

	 	b)	Partition attachment clips. 

  

	 	c)	USG “Millennia Climaplus Ceilings” tile, 2’ x 2’x  3⁄4”, kerffed and beveled edge. (eligible for LEED CI
points) 

  

	 	d)	Ceiling height 10-6”: Floor 1. 

  

	 	e)	Ceiling height 9-0”: Floors 2-4. 

  

	5)	FIRE SPRINKLER 

  

	 	a)	Drop heads from existing distribution, to be located in center of ceiling tile. 

  

	 	b)	Adjustable heads. 

  

	 	c)	Semi-recessed head model ‘H’ 2” orifice with white enamel trim. 

  

	 	d)	Record Designer: Design-Build by incumbent contractor. 

  

	6)	FINISHES 

  

	 	a)	PAINT 

  

	 	i)	One specified primer coat, plus two “Eggshell” finish coats. 

  

	 	ii)	Benjamin Moore; Ecospec Interior Line. (eligible for LEED CI points) 

  

	 	iii)	Colors to be selected by tenant from building standards. 

  

	 	b)	FLOOR COVERING 

  

	 	i)	Carpet: “Shaw”; Turn-Key Collection: “Edit”, “Equal”, or “Divide”. Direct glue down installation. (eligible for LEED CI points: 100% eco solution Q premium branded nylon fiber)

  

	 	ii)	“Shaw” guarantees it will pick up EcoWorx carpet at the end of its life, at no charge to customer, and recycle it into more EcoWorx. 

 

	 	iii)	Vinyl composition title – “Armstrong” Imperial Texture Standard Excelon 

  

	 	iv)	12“x12“x1/8” gauge tile. 

  

	 	v)	Colors to be selected by tenant from building standard. 

  

	 	c)	RUBBER BASE 

  

	 	i)	4” rubber coved base, ‘Burke’ or equal. 

  

	 	ii)	Colors to be selected by tenant from building standards. 

  

	 	d)	WINDOW COVERING 

  

	 	i)	Century Blinds perforated vinyl vertical blind. Draw and tilt function, with 3  1⁄2” curved P.V.C. vanes with perforation.

  

	 	ii)	Color: Satin White. 

  

	7)	SIGNAGE (Property Manager)  

  

	 	a)	Building standard ground floor directory tenant identification/suite number strip. 

  

	 	b)	Building standard tenant identification/suite number sign adjacent to corridor entry door. 

  

	 	c)	Outdoor illuminated signs: Negotiate with property manager. 

  

	 	i)	Power through lighting control system for automatic daily illumination. 

  

	8)	MECHANICAL SYSTEMS 

  

	 	a)	HVAC 

  

	 	i)	The shell and core has separate AC units for each floor of the building with main ducting pre-installed and with ceiling plenum return. 

 

	 	ii)	 Diffuser and Return Air Grilles: Krueger or Titus, flush with ceiling, modular, perforated

  
 SCHEDULE 2 

-2- 

	 	
type with metal frame, square neck and modular core. Furnish with factory finish to match ceiling tile and frame type to match ceiling suspension system. Supply diffusers to include 4 way
adjustable curved blades. 

  

	 	iii)	Typical Zoning Density: 750 square feet per zone, average. Corner offices and conference rooms zoned separately. 

  

	 	iv)	Return air: Provide return air grills proportionally arranged for open interior bays. Provide return air grills for each closed office. Where slab-to-slab privacy walls are 

 

	 	v)	installed, provide a “U” or “Z” lined transfer duct sized for an air velocity of 300 FPM or less. 

  

	 	vi)	Provide variable air volume (VAV) air delivery terminals tied into existing main supply duct. Provide lined discharge plenums for downstream bellmouth duct tapings. 

 

	 	vii)	Variable Air Volume Terminals: Price, Krueger or Titus, single inlet pressure independent without heat for interior zones, with 2 row hot water coil for perimeter zones and a flow cross inlet flow sensing element.

  

	 	viii)	Perimeter and interior zone VAV terminals will include a 2 row hot water heating coil with velocity reduction plenum, a 2 way pressure-independent control valve, medium mesh strainer, ball type SOVs and insulated branch
piping tied into existing hot water mains. 

  

	 	(1)	Provide air vent valves at high points in inverts for air relief. 

  

	 	ix)	For IDF rooms, server rooms and other areas with significant cooling loads, provide cooling only VAV terminals and/or supplementary cooling units. Obtain permission from and coordinate the installation of roof mounted
equipment with the property manager. 

  

	 	x)	Provide rigid spiral duct run-outs to terminals, one size larger than the terminal inlet collar for low pressure drop. Transition to terminal inlet with a long throat conical fitting. Tap runout into main duct using
bellmouth fittings. Provide a lined terminal discharge plenum fitted up to the heating coil for downstream ducts, using bellmouth fittings, collars and balancing dampers. 

 

	 	b)	CONTROL WORK 

 Control work shall include building standard Alerton BACnet
pressure-independent digital zone controllers with heating coil discharge air temperature sensors, MicroSet wall thermostats with display and buttons, UL Listed 24 VAC, 40 VA transformer, Belimo damper actuators, Belimo PICCV control valves with
actuators, installation, programming and graphics/alarm/trend updating at operator workstation. 
  

	 	i)	Tie zone controllers into the existing floor MS/TP BACnet data network at the main ducts. Insert the tenant zones into the network by pulling network cable back to the adjacent zone and running new wire to the new zone,
then picking up the existing wire again to form a daisy chain with no intermediate splices. 

  

	 	(1)	Program zone terminals identically to the base building terminals including feedback for static pressure reset, discharge air temperature reset with heating minimum air flow reset, purge-out, warm-up/cool-down, demand
controlled ventilation and other building standard control features. 

  

	 	(2)	Program the perimeter zones and gathering areas for a minimum air flow of 20% of design flow and interior open areas to zero minimum flow. All zones shall accept proportional reset from demand controlled ventilation
algorithms. 

  

	 	ii)	Provide Telaire Model 8003 CO2 sensors in tenant spaces for sensing the average CO2 levels. Provide
additional sensors in lunch rooms, conference rooms and other closed areas where more than four people can gather. 

  

	 	(1)	Program each zone to accept digital reset of the minimum air flow setting from the CO2 sensors in the related spaces. Where a CO2 sensor encompasses several related zones, link these zones to the demand controlled ventilation reset. Reset the minimums proportionally up to 40% of design flow in each zone. 

 

	 	c)	TESTING, BALANCING AND LEED CI COMMISSIONING 

  

	 	i)	Provide the services of American Companies (AABC/ACG) and Climatec, Inc. (Alerton) for combined test, balance and commissioning of zone work to meet the LEED CI standard integrating with the LEED certification for the
building shell and core. 

  

	 	ii)	Provide Title 24 static pressure optimization, purge and building standard after-hours sequences to suit the tenant and their lease arrangement. 

 

	 	iii)	Design static pressure is 1.25” WC in the main duct. This will not be adjusted higher to make undersized terminals perform. 

  

	 	iv)	Space heating water design temperatures are 160°F supply with a 30°F delta. Two-row heating coils are required. 

  

	 	v)	Space pressurization is maintained at 0.05” WC positive. 

  
 SCHEDULE 2 

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	9)	ELECTRICAL SYSTEMS 

  

	 	a)	LIGHTING FIXTURES 

  

	 	i)	2’ x 4’ Lithonia “Avante” AV-G-3-32MDR-277-GEB-W3-F32T8/TL8. 

  

	 	ii)	Three T8 fluorescent tubes; 8500K (daylight) color temperature with earthquake clips and ceiling wire. 

  

	 	iii)	Provide electronic daylight compensation for fixtures rows along the glazed perimeter walls for each exposure for LEED CI points. 

  

	 	iv)	Coverage ratio: In accordance with IES standard and Title 24 energy code. 

  

	 	b)	ELECTRICAL POWER WALL OUTLET 

  

	 	i)	‘Leviton’, Decora, receptacles self-grounding or equal, duplex, 20 amp receptacle. 

  

	 	ii)	Color: White. 

  

	 	iii)	Mounted vertically 18” A.F.F. to center of faceplate. 

  

	 	c)	ELECTRICAL FLOOR BOXES & PARTITION FEEDS 

  

	 	i)	Walker#880 SI (One Gang Box) 

  

	 	ii)	Walker #880 52 (Two Gang Box) 

  

	 	iii)	Walker#817 PC-BRN (One Gang Carpet Flange) 

  

	 	iv)	Walker # 927 PC-BRN (Two Gang Carpet Flange) 

  

	 	v)	Walker # 828 PR-BRN (Duplex receptacle with cover plate) 

  

	 	vi)	Walker # 829 PS-BRN (Telephone /Data with cover plate) 

  

	 	vii)	Walker # 829 PCK-BRN (Low tension cover plate with K.O.’s for power flex to system) 

  

	 	d)	FLUSH FLOOR-MOUNTED POKE THRU POWER WITH FLEX FEED TO ELECTRIFIED PARTITION SYSTEM 

  

	 	i)	Walker #RC-700-6A 

  

	 	e)	FLUSH FLOOR MOUNTED POKE THRU TELEPHONE/DATA 

  

	 	i)	Walker #RC-700-A-20A with COM5O. 

  

	 	ii)	Use  3⁄4” C. for telephone/data feed. 

 

	 	f)	LIGHTING CONTROL MOTION SENSORS 

  

	 	i)	Wall mounted, dual level sensor- Unenco # SOM 10-2 

  

	 	ii)	Wall mounted, single level sensor- Unenco #SOM 10-1 

  

	 	iii)	One way ceiling mount sensor—Unenco #C-500-800 

  

	 	iv)	Plenum rated (FR) wire, UL Listed transformer and control relay. 

  

	 	g)	LIGHTING CONTROL SWITCHING (for use in other areas as allowed by current Title 24 guidelines) 

  

	 	i)	Leviton Decora #5601 and 5603, White. 

  

	 	ii)	Switched AB paired in double gang box to meet Title 24 requirements. 

  

	 	iii)	Height 40” A.F.F., to centerline of switch. 

  

	 	h)	BASE BUILDING LIGHTING CONTROL SYSTEM (LEVITON) 

  

	 	i)	Route tenant light circuits (excluding emergency circuits) through the digital lighting control panel circuit relays located in each electrical room. 

 

	 	ii)	Arrange and program circuits to the building standard template and occupancy schedule (identified in the lease). 

  

	 	iii)	Provide digital low voltage programmable switches in key locations to permit tenants to turn on lights after normal hours. 

  

	 	(1)	Provide engraved plates to identify areas controlled by digital low voltage switches. 

  

	10)	TELEPHONE/DATA PROVISIONS 

  

	 	a)	Single gang wall box with  3⁄4” conduit stub sweep-out 6” above ceiling. 

 

	 	b)	Mount vertically plumb and true, 18” A.F.F. to center of faceplate. 

  

	 	c)	Faceplate color is White. 

  

	 	d)	Plenum wiring in ceiling spaces, neatly run parallel to building lines and properly hung 

  

	 	e)	Provide a two-inch (minimum) telephone conduit from the nearest floor telephone room to tenant backboard within the suite for tenant service cabling. 

 

	 	i)	Tenant provides fiber/copper cable in conduit. 

  

	 	f)	Coordinate equipment space in main telephone room with property management. 

  
 SCHEDULE 2 

-4- 

	11)	EXIT SIGNS 

  

	 	a)	Lithonia LRP-1-GC-LA-277-X2, Single Face; LRP-2-GMR-DA-277-X2, Double Face. LED illumination, RED 

  

	 	b)	Universal mounting and universal illuminated exit sign with injection molded clear polycarbonate outer housing. 

  

	 	c)	White inner stencil background with green letters. 

  

	 	d)	Provide 90 minute, 1400 lumen battery pack or connect to tenant provided common battery backed UPS. 

  

	12)	PLUMBING FIXTURES 

  

	 	a)	Kitchen sink: single basin stainless steel #SL-ADA-1921-A-GR, 6  1⁄2” DP or equal by Elkay. 

 

	 	b)	ADA compliant 2 handle faucet by Elkay or Moen. 

  

	 	c)	Garbage Disposal: In-Sink-Erator Model 777SS, 3/4 HP. 

  

	 	d)	Chronomite Labs: Model M-40-277; 11 kW electronic temperature control for coffee/lunch room sinks and dishwashers. 

  

	13)	FIRE LIFE SAFETY 

  

	 	a)	Semi-recessed fire extinguisher cabinets by Potter-Roemer, “Alta” series. Color to match adjacent wall. 

  

	 	b)	Fire/smoke detection, manual initiation and speaker/strobes are design-build to match building standard provided by incumbent contractor. 

 

	14)	SECURITY 

  

	 	a)	Card Access Control: Access after-hours is through the use of electrically coded cards in existing building card readers. 

  

	 	i)	Card controls access to main lobby entry and elevators. 

  

	 	ii)	Exit doors to stairwells and public exits are monitored with door bug sensors. 

  

	 	b)	Camera surveillance is provided for the lobbies, public areas, corridors and parking garage. Tenant provides additional cameras to suit. 

 

	15)	MISCELLANEOUS 

  

	 	a)	Tenant Improvement allowance includes working drawings, permits and fees. 

  

	 	b)	Electrical engineer to calculate lighting and receptacle loads (watts per sf) to demonstrate compliance with the lease, LEED CI and with the T24 energy code. 

 

	 	c)	Mechanical engineer to calculate heating, cooling and ventilation loads to demonstrate compliance with the lease, LEED CI and with the T24 energy code. 

 

	 	d)	Plumbing engineer to calculate fixture unit loads to demonstrate compliance with the lease, LEED CI and with the T24 energy code. 

  

	 	e)	Data/Telecom system designer to be a BICSI certified RCDD engineer, designing data distribution system in ceiling plenums in compliance with the lease, local codes and best industry workmanship standards.

  
 SCHEDULE 2 

-5- 

 SCHEDULE 3 

TIME DEADLINES 
  

			
	 Dates
	  	 Actions to be Performed

	 A. Ten (10) business days after Tenant receives the Final Working Drawings from Landlord
	  	Final Working Drawings and Final Pricing Plan to be approved by Tenant.

  
 SCHEDULE 3 

-1-

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