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                                                                   EXHIBIT 10.19

                                                               CUSTOMER NO. 1140

                            MASTER LEASE AGREEMENT

Lessor:        TRANSAMERICA BUSINESS CREDIT CORPORATION
               Riverway II
               West Office Tower
               West Higgins
               Rosemont, Illinois 60018

Lessee:        GENOMIC SOLUTIONS, INC.
               4355 Varsity Drive
               Ann Arbor, Michigan 48108

The lessor pursuant to this Master Lease Agreement ("Agreement") dated as of
June 24, 1998, is Transamerica Business Credit Corporation ("Lessor"). All
equipment, together with all present and future additions, parts, accessories,
attachments, substitutions, repairs, improvements, and replacements thereof or
thereto, which are the subject of a Lease (as defined in the next sentence)
shall be referred to as "Equipment." Simultaneous with the execution and
delivery of this Agreement, the parties are entering into one or more Lease
Schedules (each, a "Schedule") which refer to and incorporate by reference this
Agreement, each of which constitutes a lease (each, a "Lease") for the Equipment
specified therein. Additional details pertaining to each Lease are specified in
the applicable Schedule. Each Schedule that the parties hereafter enter into
shall constitute a Lease. Lessor has no obligation to enter into any additional
leases with, or extend any future financing to, Lessee.

     1. LEASE. Subject to and upon all of the terms and conditions of this
Agreement and each Schedule, Lessor hereby agrees to lease to Lessee and Lessee
hereby agrees to lease from Lessor the Equipment for the Term (as defined in
Paragraph 2 below) thereof. The timing and financial scope of Lessor's
obligation to enter into Leases hereunder are limited as set forth in the
Commitment Letter executed by Lessor and Lessee, dated as of May 5, 1998 and
attached hereto as Exhibit A (the "Commitment Letter").

     2. TERM. Each Lease shall be effective and the term of each Lease
("Term") shall commence on the commencement date specified in the applicable
Schedule and, unless sooner terminated (as hereinafter provided), shall expire
at the end of the term specified in such Schedule; provided, however, that
obligations due to be performed by Lessee during the Term shall continue until
they have been performed in full. Schedules will only be executed after the
delivery of the Equipment to Lessee or upon completion of deliveries of items of
such Equipment with aggregate cost of not less than $50,000.

     3. RENT. Lessee shall pay as rent to Lessor, for use of the Equipment
during the Term or Renewal Term (as defined in Paragraph 8), rental payments
equal to the sum of all rental payments including, without limitation, security
deposits, advance rents, and interim rents payable in the amounts and on the
dates specified in the applicable Schedule ("Rent"). If any Rent or other amount
payable by Lessee is not paid within five days after the day on which it becomes
payable, Lessee will pay on demand, as a late charge, an amount equal to 5% of
such unpaid Rent or other amount but only to the extent permitted by applicable
law. All payments provided for herein shall be payable to Lessor at its address
specified above, or at any other place designated in writing by Lessor.

     4. LEASE NOT CANCELABLE; LESSEE'S OBLIGATIONS ABSOLUTE. No Lease may be
canceled or terminated except as expressly provided herein. Lessee's obligation
to pay all Rent due or to become due hereunder shall be absolute and
unconditional and shall not be subject to any delay, reduction, set-off,
defense, counterclaim, or recoupment for any reason whatsoever, including any
failure of the Equipment or any representations by the manufacturer or the
vendor thereof. If the Equipment is unsatisfactory for any reason, Lessee shall
make any claim solely against the manufacturer or the vendor thereof and shall,
nevertheless, pay Lessor all Rent payable hereunder.

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     5. SELECTION AND USE OF EQUIPMENT. Lessee agrees that it shall be
responsible for the selection and use of, and results obtained from, the
Equipment and any other associated equipment or services.

     6. WARRANTIES. LESSOR MAKES NO REPRESENTATION OR WARRANTY, EXPRESS OR
IMPLIED, AS TO ANY MATTER WHATSOEVER, INCLUDING, WITHOUT LIMITATION, THE DESIGN
OR CONDITION OF THE EQUIPMENT OR ITS MERCHANTABILITY, SUITABILITY, QUALITY, OR
FITNESS FOR A PARTICULAR PURPOSE, AND HEREBY DISCLAIMS ANY SUCH WARRANTY. LESSEE
SPECIFICALLY WAIVES ALL RIGHTS TO MAKE A CLAIM AGAINST LESSOR FOR BREACH OF ANY
WARRANTY WHATSOEVER. LESSEE LEASES THE EQUIPMENT "AS IS." IN NO EVENT SHALL
LESSOR HAVE ANY LIABILITY, NOR SHALL LESSEE HAVE ANY REMEDY AGAINST LESSOR, FOR
ANY LIABILITY, CLAIM, LOSS, DAMAGE, OR EXPENSE CAUSED DIRECTLY OR INDIRECTLY BY
THE EQUIPMENT OR ANY DEFICIENCY OR DEFECT THEREOF OR THE OPERATION, MAINTENANCE,
OR REPAIR THEREOF OR ANY CONSEQUENTIAL DAMAGES AS THAT TERM IS USED IN SECTION
2-719(3) OF THE MODEL UNIFORM COMMERCIAL CODE, AS AMENDED FROM TIME TO TIME
("UCC"). Lessor grants to Lessee, for the sole purpose of prosecuting a claim,
the benefits of any and all warranties made available by the manufacturer or
the vendor of the Equipment to the extent assignable.

     7. DELIVERY. Lessor hereby appoints Lessee as Lessor's agent for the sole
and limited purpose of accepting delivery of the Equipment from each vendor
thereof. Lessee shall pay any and all delivery and installation charges. Lessor
shall not be liable to Lessee for any delay in, or failure of, delivery of the
Equipment.

     8. RENEWAL. So long as no Event of Default or event which, with the giving
of notice, the passage of time, or both, would constitute an Event of Default,
shall have occurred and be continuing, or the Lessee shall not have exercised
its purchase option under Paragraph 9 hereof, each Lease will automatically
renew for a term specified in the applicable Schedule (the "Renewal Term") on
the terms and conditions of this Agreement or as set forth in such Schedule;
provided, however, that Obligations due to be performed by the Lessee during the
Renewal Term shall continue until they have been performed in full.

     9. PURCHASE OPTION. So long as no Event of Default or event which, with the
giving of notice, the passage of time, or both, would constitute an Event of
Default, shall have occurred and be continuing, Lessee may, upon written notice
to Lessor received at least one hundred eighty days before the expiration of a
Term, purchase all, but not less than all, the Equipment covered by the
applicable Lease on the date specified therefor in the applicable Schedule
("Purchase Date"). The purchase price for such Equipment shall be its fair
market value as set forth in the applicable Schedule determined on an "In-place,
In-use" basis, as mutually agreed by Lessor and Lessee, or, if they cannot
agree, as determined by an independent appraiser selected by Lessor and approved
by Lessee, which approval will not be unreasonably delayed or withheld. Lessee
shall pay the cost of any such appraisal. It is hereby agreed that at the end of
the Term, the fair market value of the Equipment shall not be less than ten
percent (10%) nor more than fifteen percent (15%) of its original Equipment
Cost, as set forth on the applicable Schedule. So long as no Event of Default or
event which, with the giving of notice, the passage of time, or both, would
constitute an Event of Default shall have occurred and be continuing, Lessee
may, upon written notice to Lessor received at least one hundred eighty days
prior to the expiration of the Renewal Term, purchase all, but not less than
all, the Equipment covered by the applicable Schedule by the last date of the
Renewal Term (the "Alternative Purchase Date") at a purchase price equal to its
then fair market value on an "In-place, In-use" basis. Fair market value shall
be as mutually agreed by Lessor and Lessee, or, if they cannot agree, as
determined by an independent appraiser selected by Lessor and approved by
Lessee, which approval will not be unreasonably delayed or withheld. On the
Purchase Date or the Alternative Purchase Date, as the case may be, for any
Equipment, Lessee shall pay to Lessor the purchase price, together with all
sales and other taxes applicable to the transfer of the Equipment and any other
amount payable and arising hereunder, in immediately available funds, whereupon
Lessor shall transfer to Lessee, without recourse or warranty of any kind,
express or implied, except as to the absence of Lessor liens, all of Lessor's
right, title, and interest in and to such Equipment on an "As Is, Where Is"
basis. Lessor agrees to execute a bill of sale or other instrument reasonably
required to effect such transfer.

     10. OWNERSHIP; INSPECTION; MARKING; FINANCING STATEMENTS. Lessee shall
affix to the Equipment any labels supplied by Lessor indicating ownership of
such Equipment. The Equipment is and shall be the sole property of Lessor.
Lessee shall have no right, title, or interest therein, except as lessee

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under a Lease. The Equipment is and shall at all times be and remain personal
property and shall not become a fixture. Lessee shall obtain and record such
instruments and take such steps as may be necessary to prevent any person from
acquiring any rights in the Equipment by reason of the Equipment being claimed
or deemed to be real property. Upon request by Lessor, Lessee shall obtain and
deliver to Lessor valid and effective waivers, in recordable form, by the
owners, landlords, and mortgagees of the real property upon which the Equipment
is located or certificates of Lessee that it is the owner of such real property
or that such real property is neither leased nor mortgaged. Lessee shall make
the Equipment and its maintenance records available for inspection by Lessor
at reasonable times and upon reasonable notice. Lessee shall execute and deliver
to Lessor for filing any UCC financing statements or similar documents Lessor
may reasonably request.

     11. EQUIPMENT USE. Lessee agrees that the Equipment will be operated by
competent, qualified personnel in connection with Lessee's business for the
purpose for which the Equipment was designed and in accordance with applicable
operating instructions, laws, and government regulations, and that Lessee shall
use all reasonable precautions to prevent loss or damage to the Equipment from
fire and other hazards. Lessee shall procure and maintain in effect all orders,
licenses, certificates, permits, approvals, and consents required by federal,
state, or local laws or by any governmental body, agency, or authority in
connection with the delivery, installation, use, and operation of the Equipment.

     12. MAINTENANCE. Lessee, at its sole cost and expense, shall keep the
Equipment in a suitable environment as specified by the manufacturer's
guidelines or the equivalent, shall meet all recertification requirements, and
shall maintain the Equipment in its original condition and working order,
ordinary wear and tear excepted. At the reasonable request of Lessor, Lessee
shall furnish all proof of maintenance.

     13. ALTERATION; MODIFICATIONS; PARTS. Lessee may alter or modify the
Equipment only with the prior written consent of Lessor. Any alteration shall be
removed and the Equipment restored to its normal, unaltered condition at
Lessee's expense (without damaging the Equipment's originally intended function
or its value) prior to its return to Lessor. Any part installed in connection
with warranty or maintenance service or which cannot be removed in accordance
with the preceding sentence shall be the property of Lessor.

     14. RETURN OF EQUIPMENT. Except for Equipment that has suffered a Casualty
Loss (as defined in Paragraph 15 below) and is not required to be repaired
pursuant to Paragraph 15 below or Equipment purchased by Lessee pursuant to
Paragraph 9 above, upon the expiration of the Renewal Term of a Lease, or upon
demand by Lessor pursuant to Paragraph 22 below, Lessee shall contact Lessor for
shipping instructions and, at Lessee's own risk, immediately return the
Equipment, freight prepaid, to a location in the continental United States
specified by Lessor. At the time of such return to Lessor, the Equipment shall
(i) be in the operating order, repair, and condition as required by or specified
in the original specifications and warranties of each manufacturer and
vendor thereof, ordinary wear and tear excepted, and (ii) be capable of being
promptly assembled and operated by a third party purchaser or third party lessee
without further repair, replacement, alterations, or improvements. Except as
otherwise provided under Paragraph 9 hereof, at least one hundred eighty days
before the expiration of the Renewal Term, Lessee shall give Lessor notice of
its intent to return the Equipment at the end of such Renewal Term. During the
one hundred eighty-day period prior to the end of a Term or the Renewal Term,
Lessor and its prospective purchasers or lessees shall have, upon not less than
two business days' prior notice to Lessee and during normal business hours, or
at any time and without prior notice upon the occurrence and continuance of an
Event of Default, the right of access to the premises on which the Equipment is
located to inspect the Equipment, and Lessee shall cooperate in all other
respects with Lessor's remarketing of the Equipment. The provisions of this
Paragraph 14 are of the essence of the Lease, and upon application to any court
of equity having jurisdiction in the premises, Lessor shall be entitled to a
decree against Lessee requiring specific performance of the covenants of Lessee
set forth in this Paragraph 14. If Lessee fails to return the Equipment when
required, the terms and conditions of the Lease shall continue to be applicable
and Lessee shall continue to pay Rent until the Equipment is received by Lessor.

     15. CASUALTY INSURANCE; LOSS OR DAMAGE. Lessee will maintain, at its own
expense, liability and property damage insurance relating to the Equipment,
insuring against such risks as are customarily insured against on the type of
equipment leased hereunder by businesses in which Lessee is engaged in such
amounts, in such form, and with insurers satisfactory to Lessor; provided,
however, that the amount of

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insurance against damage or loss shall not be less than the greater of (a) the
replacement value of the Equipment and (b) the stipulated loss value of the
Equipment specified in the applicable Schedule ("Stipulated Loss Value"). Each
liability insurance policy shall provide coverage (including, without
limitation, personal injury coverage) of not less than $1,000,000 for each
occurrence, and shall name Lessor as an additional insured; and each property
damage policy shall name Lessor as sole loss payee and all policies shall
contain a clause requiring the insurer to give Lessor at least thirty days'
prior written notice of any alteration in the terms or cancellation of the
policy. Lessee shall furnish to Lessor a copy of each insurance policy (with
endorsements) or other evidence satisfactory to Lessor that the required
insurance coverage is in effect; provided, however, Lessor shall have no duty to
ascertain the existence of or to examine the insurance policies to advise Lessee
if the insurance coverage does not comply with the requirements of this
Paragraph. If Lessee fails to insure the Equipment as required, Lessor shall
have the right but not the obligation to obtain such insurance, and the cost of
the insurance shall be for the account of Lessee due as part of the next due
Rent. Lessee consents to Lessor's release, upon its failure to obtain
appropriate insurance coverage, of any and all information necessary to obtain
insurance with respect to the Equipment or Lessor's interest therein.

     Until the Equipment is returned to and received by Lessor as provided in
Paragraph 14 above, Lessee shall bear the entire risk of theft or destruction
of, or damage to, the Equipment including, without limitation, any condemnation,
seizure, or requisition of title or use ("Casualty Loss"). No Casualty Loss
shall relieve Lessee from its obligations to pay Rent except as provided in
clause (b) below. When any Casualty Loss occurs, Lessee shall immediately
notify Lessor and, at the option of Lessor, shall promptly (a) place such
Equipment in good repair and working order; or (b) pay Lessor an amount equal
to the Stipulated Loss Value of such Equipment and all other amounts (excluding
Rent) payable by Lessee hereunder, together with a late charge on such amounts
that are past due at a rate per annum equal to the rate imputed in the Rent
payments hereunder (as reasonably determined by Lessor) from the date of the
Casualty Loss through the date of payment of such amounts, whereupon Lessor
shall transfer to Lessee, without recourse or warranty (express or implied),
except as to the absence of Lessor liens, all of Lessor's interest, if any, in
and to such Equipment on an "AS IS, WHERE IS" basis and the Lease shall
terminate. Lessor agrees to execute a bill of sale or other instrument
reasonably required to effect such transfer. The proceeds of any insurance
payable with respect to the Equipment shall be applied, at the option of Lessee,
either towards (i) repair or replacement of the Equipment or (ii) payment of any
of Lessee's obligations hereunder. Lessee hereby appoints Lessor as Lessee's
attorney-in-fact to make claim for, receive payment of, and execute and endorse
all documents, checks or drafts issued with respect to any Casualty Loss under
any insurance policy relating to the Equipment.

     16. TAXES. Lessee shall pay when due, and indemnify and hold Lessor
harmless from, all sales, use, excise, and other taxes, charges, and fees
(including, without limitation, income, franchise, business and occupation,
gross receipts, licensing, registration, titling, personal property, stamp and
interest equalization taxes, levies, imposts, duties, charges, or withholdings
of any nature), and any fines, penalties, or interest thereon, imposed or levied
by any governmental body, agency, or tax authority upon or in connection with
the Equipment, its purchase, ownership, delivery, leasing, possession, use, or
relocation of the Equipment or otherwise in connection with the transactions
contemplated by each Lease or the Rent thereunder, excluding taxes on or
measured by the net income of Lessor. Upon request, Lessee will provide proof of
payment. Unless Lessor elects otherwise, Lessee will pay all property taxes on
the Equipment. Lessee shall timely prepare and file all reports and returns
which are required to be made with respect to any obligation of Lessee under
this Paragraph 16. Lessee shall, to the extent permitted by law, cause all
billings of such fees, taxes, levies, imposts, duties, withholdings, and
governmental charges to be made to Lessor in care of Lessee. Upon request,
Lessee will provide Lessor with copies of all such billings.

     17. LESSOR'S PAYMENT. If Lessee fails to perform its obligations under
Paragraph 15 or 16 above, or Paragraph 23 below, Lessor shall have the right to
substitute performance, in which case Lessee shall immediately reimburse Lessor
therefor.

     18. GENERAL INDEMNITY. Each Lease is a net lease. Therefore, Lessee shall
indemnify Lessor and its successors and assigns against, and hold Lessor and its
successors and assigns harmless from, any and all claims, actions, damages,
obligations, liabilities, and all costs and expenses, including, without
limitation, reasonable legal fees incurred by Lessor or its successors and
assigns arising out of each Lease including, without limitation, the purchase,
ownership, delivery, lease, possession, maintenance, condition, use, or return
of the Equipment, or arising by operation of law, except that Lessee shall not
be liable for any claims, actions, damages,

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obligations, and costs and expenses determined by a non-appealable, final order
of a court of competent jurisdiction to have occurred as a result of the gross
negligence or willful misconduct of Lessor or its successors and assigns. Lessee
agrees that upon written notice by Lessor of the assertion of any claim, action,
damage, obligation, liability, or lien for which Lessor is entitled to
indemnification hereunder, Lessee shall assume full responsibility for the
defense thereof, provided that Lessor's failure to give such notice shall not
limit or otherwise affect its rights hereunder, except to the extent that
Lessee's rights have been prejudiced by such failure. Any payment pursuant to
this Paragraph (except for any payment of Rent) shall be of such amount as shall
be necessary so that, after payment of any taxes required to be paid thereon by
Lessor, including taxes on or measured by the net income of Lessor, the balance
will equal the amount due hereunder. The provisions of this Paragraph with
regard to matters arising during a Lease shall survive the expiration or
termination of such Lease. Notwithstanding the foregoing, Lessor shall not be
entitled to recover from Lessee an amount in excess of the amount necessary to
put Lessor in the same position it would have been in had it not incurred the
claim, action, damage, obligation, liability or lien for which its being
indemnified by Lessee hereunder.

     19. ASSIGNMENT BY LESSEE. Lessee shall not, without the prior written
consent of Lessor, (a) assign, transfer, pledge, or otherwise dispose of any
Lease or Equipment, or any interest therein; (b) sublease or lend any Equipment
or permit it to be used by anyone other than Lessee and its employees; or (c)
move any Equipment from the location specified for it in the applicable
Schedule, except that Lessee may move Equipment to another location within the
United States provided that Lessee has delivered to Lessor (A) prior written
notice thereof and (B) duly executed financing statements and other agreements
and instruments (all in form and substance satisfactory to Lessor) necessary or,
in the opinion of the Lessor, desirable to protect Lessor's interest in such
Equipment. Notwithstanding anything to the contrary in the immediately preceding
sentence, Lessee may keep any Equipment consisting of motor vehicles or rolling
stock at any location in the United States.

     20. ASSIGNMENT BY LESSOR. Lessor may assign its interest or grant a
security interest in any Lease and the Equipment individually or together, in
whole or in part. If Lessee is given written notice of any such assignment, it
shall immediately make all payments of Rent and other amounts hereunder directly
to such assignee. Each such assignee shall have all of the rights of Lessor
under each Lease assigned to it. Lessee shall not assert against any such
assignee any set-off, defense, or counterclaim that Lessee may have against
Lessor or any other person.

     21. DEFAULT; NO WAIVER. Lessee or any guarantor of any or all of the
obligations of Lessee hereunder (together with Lessee, the "Lease Parties")
shall be in default under each Lease upon the occurrence of any of the following
events (each, an "Event of Default"): (a) Lessee fails to pay within two days
after notice of failure to pay when due any amount required to be paid by Lessee
under or in connection with any Lease; (b) any of the Lease Parties fails to
perform in any material respect any other provision under or in connection with
a Lease or violates in any material respect any of the covenants or agreements
of such Lease Party under or in connection with a Lease, and such failure to
perform or violation is not cured within fifteen (15) days after written notice;
(c) any representation made or financial information delivered or furnished by
any of the Lease Parties under or in connection with a Lease shall prove to have
been inaccurate in any material respect when made; (d) any of the Lease Parties
makes an assignment for the benefit of creditors, whether voluntary or
involuntary, or consents to the appointment of a trustee or receiver, or if
either shall be appointed for any of the Lease Parties or for a substantial part
of its property without its consent and, in the case of any such involuntary
proceeding, such proceeding remains undismissed or unstayed for sixty days
following the commencement thereof, (e) any petition or proceeding is filed by
or against any of the Lease Parties under any Federal or State bankruptcy or
insolvency code or similar law and, in the case of any such involuntary petition
or proceeding, such petition or proceeding remains undismissed or unstayed for
sixty days following the filing or commencement thereof, or any of the Lease
Parties takes any action authorizing any such petition or proceeding; (f) any of
the Lease Parties fails to pay when due any indebtedness in an amount in excess
of $200,000 for borrowed money or under conditional sales or installment sales
contracts or similar agreements, leases, or obligations evidenced by bonds,
debentures, notes, or other similar agreements or instruments to any creditor
(including Lessor under any other agreement) after any and all applicable cure
periods therefor shall have elapsed; (g) any judgment shall be rendered against
any of the Lease Parties which shall remain unpaid or unstayed for a period of
sixty days; (h) any of the Lease Parties shall dissolve, liquidate, wind up or
cease its business, sell or otherwise dispose of all or substantially all of its
assets; (i) any of the Lease Parties shall amend or modify its name, unless such
Lease Party delivers to Lessor, thirty days prior to any such proposed amendment
or modification, written notice of such amendment or modification and within ten
days before

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such amendment or modification delivers executed financing statements (in form
and substance satisfactory to the Lessor); (j) any of the Lease Parties shall
suffer any loss or suspension of any material license, permit, or other right or
asset necessary to the profitable conduct of its business, fail generally to pay
its debts as they mature, or call a meeting for purposes of compromising its
debts; (l) any of the Lease Parties shall deny or disaffirm its obligations
hereunder or under any of the documents delivered in connection herewith; or (k)
any of the Lease Parties suffers a material adverse change in the business,
prospects, operations, results of operations, assets, liabilities, or condition
(financial or otherwise).

     22. REMEDIES. Upon the occurrence and continuation of an Event of Default,
Lessor shall have the right, in its sole discretion, to exercise any one or more
of the following remedies: (a) terminate each Lease; (b) declare any and all
Rent and other amounts then due and any and all Rent and other amounts to become
due under each Lease (collectively, the "Lease Obligations") immediately due and
payable; (c) take possession of any or all items of Equipment, wherever located,
without demand, notice, court order, or other process of law, and without
liability for entry to Lessee's premises, or otherwise; (d) demand that Lessee
immediately return any or all Equipment to Lessor in accordance with Paragraph
14 above, and, for each day that Lessee shall fail to return any item of
Equipment, Lessor may demand an amount equal to the Rent payable for such
Equipment in accordance with Paragraph 14 above; (e) lease, sell, or otherwise
dispose of the Equipment in a commercially reasonable manner, with or without
notice and on public or private bid, (f) recover the following amounts from the
Lessee (as damages, including reimbursement of costs and expenses, liquidated
for all purposes and not as a penalty): (i) all costs and expenses of Lessor
reimbursable to it hereunder, including, without limitation, expenses of
disposition of the Equipment, legal fees, and all other amounts specified in
Paragraph 23 below; (ii) an amount equal to the sum of (A) any accrued and
unpaid Rent through the later of (1) the date of the applicable default, (2) the
date that Lessor has obtained possession of the Equipment, or (3) such other
date as Lessee has made an effective tender of possession of the Equipment to
Lessor (the "Default Date") and (B) if Lessor resells or re-lets the Equipment,
Rent at the periodic rate provided for in each Lease for the additional period
that it takes Lessor to resell or re-let all of the Equipment; (iii) the present
value of all future Rent reserved in the Leases and contracted to be paid over
the unexpired Term of the Leases discounted at five percent compound interest;
(iv) the present value of the reversionary value of the Equipment as of the
expiration of the Term of the applicable Lease as set forth on the applicable
Schedule; and (v) any indebtedness for Lessee's indemnity under Paragraph 18
above, plus a late charge at the rate specified in Paragraph 3 above, less the
amount received by Lessor, if any, upon sale or re-let of the Equipment; and (g)
exercise any other right or remedy to recover damages or enforce the terms of
the Leases. Upon the occurrence and continuance of an Event of Default, Lessor
shall have the right, whether or not Lessor has made any demand or the
obligations of Lessee hereunder have matured, to appropriate and apply to the
payment of the obligations of Lessee hereunder all security deposits and other
deposits (general or special, time or demand, provisional or final) now or
hereafter held by and other indebtedness or property now or hereafter owing by
Lessor to Lessee. Lessor may pursue any other rights or remedies available at
law or in equity, including, without limitation, rights or remedies seeking
damages, specific performance, and injunctive relief. Any failure of Lessor to
require strict performance by Lessee, or any waiver by Lessor of any provision
hereunder or under any Schedule, shall not be construed as a consent or waiver
of any other breach of the same or of any other provision. Any amendment or
waiver of any provision hereof or under any Schedule or consent to any departure
by Lessee herefrom or therefrom shall be in writing and signed by Lessor.
Notwithstanding the foregoing, Lessor shall not be entitled to recover an amount
in excess of the amount it would have received had each Lease been fully
performed in a timely manner for its full term, plus any costs incurred in
connection with the Leases.

     No right or remedy is exclusive of any other provided herein or permitted
by law or equity. All such rights and remedies shall be cumulative and may be
enforced concurrently or individually from time to time.

     23. LESSOR'S EXPENSE. Lessee shall pay Lessor on demand all costs and
expenses (including legal fees and expenses) incurred in connection with the
preparation, execution and delivery of this Agreement and any other agreements
and transactions contemplated hereby, which expenses shall not exceed  $2,500
without the written consent of Lessee and all costs and expenses in protecting
and enforcing Lessor's rights and interests in each Lease and the equipment,
including, without limitation, legal, collection, and remarketing fees and
expenses incurred by Lessor in enforcing the terms, conditions, or provisions of
each Lease or upon the occurrence and continuation of an Event of Default.

     24. LESSEE'S WAIVERS. To the extent permitted by applicable law, Lessee
hereby waives any and all rights and remedies conferred upon a lessee by
Sections 2A-503 through 2A-522 of the UCC.

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To the extent permitted by applicable law, Lessee also hereby waives any rights
now or hereafter conferred by statute or otherwise which may require Lessor to
sell, lease, or otherwise use any Equipment in mitigation of Lessor's damages as
set forth in Paragraph 22 above or which may otherwise limit or modify any of
Lessor's rights or remedies under Paragraph 22. Any action by Lessee against
Lessor for any default by Lessor under any Lease shall be commenced within two
years after any such cause of action accrues.

     25. NOTICES; ADMINISTRATION. Except as otherwise provided herein, all
notices, approvals, consents, correspondence, or other communications required
or desired to be given hereunder shall be given in writing and shall be
delivered by overnight courier, hand delivery, or certified or registered mail,
postage prepaid, if to Lessor, then to Transamerica Technology Finance Division,
76 Batterson Park Road, Farmington, Connecticut 06032, Attention: Assistant
Vice President, Lease Administration, if to Lessee, then to Genomic Solutions,
Inc., 4355 Varsity Drive, Ann Arbor, Michigan 48108, Attention: Chief Financial
Officer or such other address as shall be designated by Lessee or Lessor in
writing to the other party. All such notices and correspondence shall be
effective when received.

     26. REPRESENTATIONS. Lessee represents and warrants to Lessor that (a)
Lessee is duly organized, validly existing, and in good standing under the laws
of the State of its incorporation; (b) the execution, delivery, and performance
by Lessee of this Agreement are within Lessee's powers, have been duly
authorized by all necessary action, and do not and will not contravene (i)
Lessee's organizational documents or (ii) any law, regulation, rule, or
contractual restriction binding on or affecting Lessee; (c) no authorization or
approval or other action by, and no notice to or filing with, any
governmental authority or regulatory body is required for the due execution,
delivery, and performance by Lessee of this Agreement; (d) each Lease
constitutes the legal, valid, and binding obligations of Lessee enforceable
against Lessee in accordance with its terms; (e) the cost of each item of
Equipment does not exceed the fair and usual price for such type of equipment
purchased in like quantity and reflects all discounts, rebates, and allowances
for the Equipment (including, without limitation, discounts for advertising,
prompt payment, testing, or other services) given to the Lessee by the
manufacturer, supplier, or any other person; and (f) all information supplied by
Lessee to Lessor in connection herewith is correct in all material respects and
does not omit any material statement necessary to insure that the information
supplied is not misleading.

     27. FURTHER ASSURANCES. Lessee, upon the request of Lessor, will execute,
acknowledge, record, or file, as the case may be, such further documents and do
such further acts as may be reasonably necessary, desirable, or proper to carry
out more effectively the purposes of this Agreement. Lessee hereby appoints
Lessor as its attorney-in-fact to execute on behalf of Lessee and authorizes
Lessor to file without Lessee's signature any UCC financing statements and
amendments relating to the Equipment Lessor reasonably deems advisable.

     28. FINANCIAL STATEMENTS. Lessee shall deliver to Lessor: (a) as soon as
available, but not later than 120 days after the end of each fiscal year of
Lessee and its consolidated subsidiaries, the consolidated balance sheet, income
statement, and statements of cash flows and shareholders equity for Lessee and
its consolidated subsidiaries (the "Financial Statements") for such year,
reported on by independent certified public accountants without an adverse
qualification; and (b) as soon as available, but not later than 60 days after
the end of each of the first three fiscal quarters in any fiscal year of Lessee
and its consolidated subsidiaries, the Financial Statements for such fiscal
quarter, together with a certification duly executed by a responsible officer of
Lessee that such Financial Statements have been prepared in accordance with
generally accepted accounting principles and are fairly stated in all material
respects (subject to normal year-end audit adjustments). Lessee shall also
deliver to Lessor as soon as available copies of all press releases and other
similar communications issued by Lessee.

     29. CONSENT TO JURISDICTION. Lessee irrevocably submits to the jurisdiction
of any Illinois state or federal court sitting in Illinois for any action or
proceeding arising out of or relating to this Agreement or the transactions
contemplated hereby, and Lessee irrevocably agrees that all claims in respect of
any such action or proceeding may be heard and determined in such Illinois state
or federal court.

     30. WAIVER OF JURY TRIAL. LESSEE AND LESSOR IRREVOCABLY WAIVE ALL RIGHT TO
TRIAL BY JURY IN ANY ACTION, PROCEEDING, OR COUNTERCLAIM ARISING OUT OF OR
RELATING TO THIS AGREEMENT OR THE TRANSACTIONS CONTEMPLATED HEREBY.

                                       7

<PAGE>   8

     31. FINANCE LEASE. Lessee and Lessor agree that each Lease is a "Finance
Lease" as defined by Section 2A-103(g) of the UCC. Lessee acknowledges that
Lessee has reviewed and approved each written Supply Contract (as defined by UCC
2A-103(y)) covering Equipment purchased from each "Supplier" (as defined by UCC
2A-103(x)) thereof.

     32. NO AGENCY. Lessee acknowledges and agrees that neither the manufacturer
or supplier, nor any salesman, representative, or other agent of the
manufacturer or supplier, is an agent of Lessor. No salesman, representative, or
agent of the manufacturer or supplier is authorized to waive or alter any term
or condition of this Agreement or any Schedule and no representation as to the
Equipment or any other matter by the manufacturer or supplier shall in any way
affect Lessee's duty to pay Rent and perform its other obligations as set forth
in this Agreement or any Schedule.

     33. SPECIAL TAX INDEMNIFICATION. Lessee acknowledges that Lessor, in
determining the Rent due hereunder, has assumed that certain tax benefits as are
provided to an owner of property under the Internal Revenue Code of 1986, as
amended (the "Code"), and under applicable state tax law, including, without
limitation, depreciation deductions under Section 168(b) of the Code, and
deductions under Section 163 of the Code in an amount at least equal to the
amount of interest paid or accrued by Lessor with respect to any indebtedness
incurred by Lessor in financing its purchase of the Equipment, are available to
Lessor as a result of the lease of the Equipment. In the event Lessor is unable
to obtain such tax benefits solely as a result of an act or omission of Lessee
which Lessee is unable to cure after having a reasonable opportunity to do so,
is required to include in income any amount other than the Rent, or is required
to recognize income in respect of the Rent earlier than anticipated pursuant to
this Agreement, Lessee shall pay Lessor additional rent ("Additional Rent") in a
lump sum in an amount needed to provide Lessor with the same after-tax yield and
after-tax cash flow as would have been realized by Lessor had Lessor (i) been
able to obtain such tax benefits, (ii) not been required to include any amount
in income other than the Rent, and (iii) not been required to recognize income
in respect of the Rent earlier than anticipated pursuant to this Agreement. The
Additional Rent shall be computed by Lessor, which computation, absent manifest
error, shall be binding on Lessee. The Additional Rent shall be due immediately
upon written notice by Lessor to Lessee of Lessor's inability to obtain tax
benefits, the inclusion of any amount in income other than the Rent or the
recognition of income in respect of the Rent earlier than anticipated pursuant
to this Agreement. The provisions of this Paragraph 33 shall survive for two
years after the termination of this Agreement.

     34. GOVERNING LAW; SEVERABILITY. EACH LEASE SHALL BE GOVERNED BY THE LAWS
OF THE STATE OF ILLINOIS WITHOUT GIVING EFFECT TO THE CONFLICT OF LAW
PRINCIPLES THEREOF. IF ANY PROVISION SHALL BE HELD TO BE INVALID OR
UNENFORCEABLE, THE VALIDITY AND ENFORCEABILITY OF THE REMAINING PROVISIONS SHALL
NOT IN ANY WAY BE AFFECTED OR IMPAIRED.

LESSEE ACKNOWLEDGES THAT LESSEE HAS READ THIS AGREEMENT AND THE SCHEDULE HERETO,
UNDERSTANDS THEM, AND AGREES TO BE BOUND BY THEIR TERMS AND CONDITIONS. FURTHER,
LESSEE AND LESSOR AGREE THAT THIS AGREEMENT, THE SCHEDULES DELIVERED IN
CONNECTION HEREWITH FROM TIME TO TIME, AND THE COMMITMENT LETTER ARE THE
COMPLETE AND EXCLUSIVE STATEMENT OF THE AGREEMENT BETWEEN THE PARTIES,
SUPERSEDING ALL PROPOSALS OR PRIOR AGREEMENTS, ORAL OR WRITTEN, AND ALL OTHER
COMMUNICATIONS BETWEEN THE PARTIES RELATING TO THE SUBJECT MATTER HEREOF. SHOULD
THERE EXIST ANY INCONSISTENCY BETWEEN THE TERMS OF THE COMMITMENT LETTER AND
THIS AGREEMENT, THE TERMS OF THIS AGREEMENT SHALL PREVAIL.

                                       8

<PAGE>   9

     IN WITNESS WHEREOF, the parties hereto have executed or caused this
Agreement to be duly executed by their duly authorized officers as of the
date first written above.

                                          GENOMIC SOLUTIONS, INC.

                                          By: /s/ Steven J. Richalsky
                                             -----------------------------------
                                            Name:  Steven J. Richalsky
                                            Title: Chief Financial Officer
                                          Federal Tax ID: 38-3383038

                                          TRANSAMERICA BUSINESS CREDIT
                                          CORPORATION

                                          By: /s/ Gary P. Moro
                                             -----------------------------------
                                            Name:  Gary P. Moro
                                            Title: Vice President

                                       9
<PAGE>   10

                           FIRST AMENDMENT TO MASTER
                                LEASE AGREEMENT

    THIS FIRST AMENDMENT to MASTER LEASE AGREEMENT (the "Amendment"), dated as
of October 13, 1999, by and between Genomic Solutions, Inc. (the "Lessee"), a
Delaware Corporation, having its principal place of business and chief executive
office at 4355 Varsity Drive, Ann Arbor, Michigan 48108, and TRANSAMERICA
BUSINESS CREDIT CORPORATION (the "Lessor"), a Delaware Corporation, having its
principal office at Riverway II, West Office Tower, 9399 West Higgins Road,
Rosemont, Illinois, 60018.

                                  WITNESSETH:

    WHEREAS, the Lessee and the Lessor are parties to Master Lease Agreement,
dated as of June 24, 1998 (as amended, the "Lease Agreement"; capitalized terms
used herein shall have the meanings assigned to such terms in the Lease
Agreement unless otherwise defined herein); and

    WHEREAS, the parties hereto desire to amend the Lease Agreement in the
manner set forth herein.

    NOW, THEREFORE, in consideration of the foregoing and for other good and
valuable consideration, the Lessee and Lessor hereby agree as follows:

    1.  AMENDMENT TO LEASE AGREEMENT.  Effective as of the date this
Amendment is fully executed by the Lessor and Lessee hereof, and subject to the
satisfaction of the Lessee of conditions as determined by Lessor, the Lease
Agreement is hereby amended as follows:

        (a)     The paragraph entitled "Lease" is hereby deleted in its
entirety and the following is inserted in lieu thereof:

        1.      LEASE. Subject to and upon all of the terms and conditions of
this Agreement and each Schedule, Lessor hereby agrees to lease to Lessee and
Lessee hereby agrees to lease from Lessor the Equipment for the Term (as
defined in Paragraph 2 below) thereof. The timing and financial scope of
Lessor's obligation to enter into Leases hereunder are limited as set forth in
the Commitment Letters executed by Lessor and Lessee, dated as of May 5, 1998
and September 23, 1999 and attached hereto as Exhibit A and Exhibit B
(collectively the "Commitment Letter").

    2.  REPRESENTATIONS AND WARRANTIES OF THE LESSEE. The Lessee represents and
warrants as follows:

        (a)     Since June 24, 1998, there has occurred no development, event
or change that has had or could reasonably be expected to have a Material
Adverse Effect.

        (b)     No Default or Event of Default has occurred and is continuing.

        (c)     The representations and warranties of such Lessee contained in
Section 26 of the Lease Agreement are true and correct in all material respects
on the date hereof as though made on and as of the date hereof, except to the
extent that such representation and warranties expressly relate solely to an
earlier date (in which case such representations and warranties were true and
correct on and as of such earlier date).

        (d)     This Amendment constitutes the legal, valid and binding
obligation of such Lessee, enforceable against the Lessee in accordance with
its terms, except as enforceablility may be limited by bankruptcy, insolvency
and other laws affecting creditors' rights generally and by general principles
of equity.

                                      -1-
<PAGE>   11
     3.   EXPENSES.   The Lessee shall pay for all of the reasonable costs and
expenses incurred by the Lessor in connection with the transactions
contemplated by the Amendment, including, without limitation, the reasonable
fees and expenses of counsel to the Lessor.

     4.   MISCELLANEOUS.

          (a)  Except as expressly amended herein, all of the terms and
provisions of the Lease Agreement and the other Lease Documents are ratified and
confirmed in all respects and shall remain in full force and effect.

          (b)  Upon the effectiveness of this Amendment, all references in the
Lease Documents to the Lease Agreement shall mean the Lease Agreement as amended
by this Amendment and all references in the Lease Agreement to the "this
Agreement", "hereof", "herein", or similar terms, shall mean and refer to the
Lease Agreement as amended by this Amendment.

          (c)  The execution, delivery and effectiveness of this Amendment shall
not, except as expressly provided herein, operate as an amendment to or waiver
of any right, power or remedy of the Lessor under any of the Lease Documents, or
constitute an amendment or waiver of any provision of any of the Lease
Documents.

          (d)  This Amendment may be executed by the parties hereto individually
or in combination, in one or more counterparts, each of which shall be an
original and all of which shall constitute one and the same agreement. This
Amendment may be executed and delivered by telecopier with the same force and
effect as if the same were a fully executed and delivered original manual
counterpart.

          (e)  This Amendment shall constitute a Lease Document.

     5.   GOVERNING LAW. THE VALIDITY, INTERPRETATION AND ENFORCEMENT OF THIS
AMENDMENT SHALL BE GOVERNED BY THE LAWS OF THE STATE OF ILLINOIS WITHOUT GIVING
EFFECT TO THE CONFLICTS OF LAW PRINCIPLES THEREOF.
<PAGE>   12

                  IN WITNESS WHEREOF, the parties hereto have caused this
Amendment to be duly executed and delivered by their respective duly authorized
officers as of the date first above written.

                                             LESSEE

                                             GENOMIC SOLUTIONS, INC.

                                             By: /s/ Steven J. Richvalsky
                                                ----------------------------
                                                Name:  Steven J. Richvalsky
                                                Title: Executive V.P. &
                                                       Chief Financial Officer

                                             Hereunto Duly Authorized

                                             LESSOR

                                             TRANSAMERICA BUSINESS CREDIT
                                             CORPORATION

                                             By: /s/ Gary P. Moro
                                                -----------------------------
                                                Name:  Gary P. Moro
                                                Title: Senior Vice President

                                             Hereunto Duly Authorized<PAGE>   1

                                                                   EXHIBIT 10.20
                              HEWITSON BECKE + SHAW
                                   SOLICITORS

                            GENOMIC SOLUTIONS LIMITED

                                 SALE OF SHARES
                           IN HD TECHNOLOGIES LIMITED

                                  JANUARY 2000

CONTENTS:

1. SHARE SALE AGREEMENT-   (25.1.00) - between Genomic Solutions Limited (1),
                           SC Davis and AD Hoffmann (2) and HD Technologies
                           Limited (3)

2. LICENCE AGREEMENT:-     (25.1.00) - between Genomic Solutions Limited (1)
                           and HD Technologies Limited (2)

3. 2 X SIDE LETTERS from Thermo Quest:
          a) re: Collaboration Agreement (16.4.98)
          b) re: Contract Manufacturing Agreement (13.7.99)

4. MISCELLANEOUS PAPERS:
          a) Notice by GSL of removal of P.N. King as Nominated Director of HDT
          b) Form 288(b)
          c) Copy letter from Nat West Bank Plc
          d) Form of release - White Pines
          e) 2 x Stock transfer forms

5. CONTRACT MANUFACTURING AGREEMENT:- (13.7.99) - copy included for completeness

<PAGE>   2

                              DATED 25 January 2000
                              ---------------------

                           GENOMIC SOLUTIONS LIMITED        (1)

                                   S C DAVIS                (2)

                                  A D HOFFMAN

                                    - and -

                          H D TECHNOLOGIES LIMITED          (3)

                            -------------------------

                                   AGREEMENT
                            for the sale of shares in
                             HD Technologies Limited

                            -------------------------

                                 tumer parkinson
                                   Solicitors
                                Hollins Chambers
                                64a Bridge Street
                                   Manchester
                                     M3 3BA

                                    Ref: NGM

<PAGE>   3

THIS AGREEMENT is made on 25th January 2000
--------------

BETWEEN:
-------

(1)   GENOMIC SOLUTIONS LIMITED (No 2315315) whose registered office is at
      Blackstone Road, Huntingdon, Cambridgeshire, PE18 6EF ("GSL");

(2)   The persons whose names and addresses are set out in Schedule 1 ("THE
      PURCHASERS"); and

(3)   H D TECHNOLOGIES LIMITED (No 2916498) whose registered office is at 3
      Chester Road, Neston, South Wirral, Cheshire, L64 9PA ("THE COMPANY").

WHEREAS:
-------

Genomic wishes to sell and the Purchasers wish to acquire the Sale Shares (as
hereinafter defined) on and subject to the terms of this Agreement.

NOW IT IS HEREBY AGREED as follows:

1.    DEFINITIONS AND INTERPRETATION

1.1   In this Agreement, unless the context otherwise requires:

      (a)   the following words have the following meanings:

            "BUSINESS DAY" means a day (other than Saturday or Sunday) when
            banks are open for ordinary banking business in London;

            "COLLABORATION AGREEMENT means the collaboration agreement dated
            16 April 1998 between the Company (1) and GSL (2);

            "CONTRACT MANUFACTURING AGREEMENT" means the contract manufacturing
            agreement dated 13 July 1999 between the Company (1) and GSL (2);

            "COMPLETION" means completion of the sale and purchase of the Sale
            Shares in accordance with clause 5;

            "ENCUMBRANCE" includes any interest or equity of any person
            (including any right to acquire, option or right of pre-emption) or
            any mortgage, charge, pledge, lien, assignment, hypothecation,
            security interest (including any created by law), title retention or
            other security agreement or arrangement or a rental, hire purchase,
            credit sale or other agreement for payment on deferred terms;

<PAGE>   4

     "GROUP" means either the GSL Group or the ThermoQuest Group, according to
     the context;

     "GSL GROUP" means:

     (a) GSL;

     (b) any Holding Company of GSL from time to time;

     (b) any Subsidiary from time to time of such Holding Company; and

     (c) any Subsidiary from time to time of GSL,

     "GSI" means Genomic Solutions Inc;

     "HOLDING COMPANY" AND "SUBSIDIARY" have the meanings given to them in
     section 736 of the Companies Act 1985;

     "OPTION AGREEMENTS" means the non-qualified stock option agreements in the
     agreed form relating to the granting of options to purchase common stock of
     Genomic Solutions Inc in favour of each of the Purchasers;

     "SALE SHARES" means the 300 Convertible Redeemable Preference Shares of
     Pound Sterling 1 each of the Company registered in the name of GSL whether
     or not converted;

     "THE SUBSCRIPTION AGREEMENT" means the subscription agreement dated 16
     April 1998 made between GSL (1) GSI (2) the Company (3) and the Purchasers
     (4);

     "THE THERMOQUEST AGREEMENT" means an agreement proposed to be entered into
     between the Purchasers (1) and ThermoQuest or any member of the ThermoQuest
     Group (2);

     "THERMOQUEST" means ThermoQuest Corporation;

     "THERMOQUEST GROUP" means:

     (a) ThermoQuest;

     (b) any Holding Company of ThermoQuest from time to time;

     (c) any Subsidiary from time to time of such Holding Company; and

     (d) any Subsidiary from time to time of ThermoQuest;

     "THE WARRANTIES" means the warranties, undertakings and representations set
     out in clause 6;

<PAGE>   5

          (b)  any reference to a recital, clause or Schedule is to the relevant
               recital, clause or Schedule of or to this Agreement and any
               reference to a sub-clause or paragraph is to the relevant
               sub-clause or paragraph of the clause or Schedule in which it
               appears;

          (c)  the clause headings are included for convenience only and shall
               not affect the interpretation of this Agreement;

          (d)  use of the singular includes the plural and vice versa;

          (e)  use of any gender includes the other genders;

          (f)  any reference to "persons" includes natural persons, firms,
               partnerships, companies, corporations, associations,
               organisations, governments, states, foundations and trusts (in
               each case whether or not having separate legal personality);

          (g)  any reference to a document being "in the agreed form" means a
               document in a form agreed by the parties and initialled by, or on
               behalf of, all of them for the purpose of identification as such;

          (h)  any phrase introduced by the terms "including", "include", "in
               particular" or any similar expression shall be construed as
               illustrative and shall not limit the sense of the words preceding
               those terms;

          (i)  the Schedules form part of this Agreement and shall have effect
               as if set out in full in the body of this Agreement and any
               reference to this Agreement includes the Schedules.

2.   SALE OF SHARES

2.1  Subject to the terms of this Agreement, GSL with full title guarantee shall
     sell and the Purchasers shall relying on the Warranties purchase, free from
     all Encumbrances and together with all rights now or hereafter attaching
     thereto, the Sale Shares.

2.2  Neither the Purchasers nor GSL shall be obliged to complete the purchase of
     any of the Sale Shares unless the purchase of all the Sale Shares is
     completed simultaneously.

3.   CONSIDERATION

3.1  The total consideration for the Sale Shares shall be the sum of US
     $600,000.

4.   CONDITION

4.1  Completion is conditional upon the ThermoQuest Agreement being entered into
     and becoming, in accordance with its terms, unconditional in all respects

<PAGE>   6

     (other than in respect of any condition relating to the Completion of this
     Agreement) and in the event that the foregoing condition shall not have
     been satisfied on or before 29 February 2000 this Agreement shall lapse and
     no party shall make any claim against any other in respect hereof, save for
     any antecedent breach.

5.   COMPLETION

5.1  Completion shall take place at the offices of the Company's solicitors,
     being Hollins Chambers, 64a Bridge Street, Manchester, M3 3BA.

5.2  On Completion GSL shall deliver to the Purchaser:

     (a)  duly executed transfers of the Sale Shares by the registered holder
          thereof in favour of the Purchasers or their nominees together with
          the relative share certificate;

     (b)  such waivers or consents as the Purchasers may require to enable the
          Purchasers or its nominees to be registered as holders of the Sale
          Shares; and

     (c)  notification in accordance with the Articles of Association of the
          Company removing the Nominated Director (as defined in the
          Subscription Agreement);

     (d)  a duly executed licence in the form set out in Schedule 2.

5.3  On Completion the Purchasers shall:

     (a)  pay the consideration for the Sale Shares as provided by clause 3,
          payment to be made by way of telegraphic transfer to the client
          account of Messrs Hewitson Becke and Shaw, Cambridge, Solicitors; and

     (b)  deliver to GSL a duly executed licence in the form set out in Schedule
          2.

5.4  GSL shall procure that GSI shall deliver to the Purchasers as soon as
     practicable following Completion amended Option Agreements in a form
     acceptable to the Purchasers providing, inter alia, for such agreements to
     subsist notwithstanding the employment of the Purchasers by a member of the
     ThermoQuest Group.

5.5  If in any respect the obligations of GSL or the Purchasers are not complied
     with on the date of Completion the party not in default may:

     (a)  defer Completion to a date not more than 28 days after the date of
          Completion (and so that the provisions of this clause 5.5, apart from
          this item, shall apply to Completion as so deferred); or

<PAGE>   7

     (b)  proceed to Completion so far as practicable (without prejudice to its
          rights hereunder); or

     (c)  rescind this Agreement.

6.   WARRANTIES

6.1  GSL warrants, represents and undertakes that:

     (a)  GSL is the beneficial and legal owner of the Sale Shares and is
          entitled to sell the Sale Shares will full title guarantee to the
          Purchasers free from all Encumbrances without the consent of any third
          party;

     (b)  GSL has full power and authority to enter into this Agreement, and any
          other documents to be executed in connection with it, all of which
          constitute (or will when executed constitute) legal and valid binding
          obligations on it enforceable in accordance with their respective
          terms;

     (c)  the Sale Shares constitute the whole of the issued share capital of
          the Company under the legal or beneficial ownership or control of GSL
          and are fully paid;

     (d)  no member of the GSL Group has the right (whether exercisable now or
          in the future and whether contingent or not) to call for the
          allotment, conversion, issue, sale or transfer or any share or loan
          capital or any other security giving rise to a right over the capital
          of the Company under any other agreement (including conversion rights
          or rights of pre-emption).

7.   RELEASE

7.1  In consideration of the Purchasers entering into this Agreement, GSL hereby
     irrevocably releases the Company and the Purchasers from all and any
     obligations and liabilities to GSL incurred by the Company and/or the
     Purchasers pursuant to the Subscription Agreement including, without
     limitation, from any obligation to enter into any negotiations concerning a
     licence for the manufacture and exploitation of the Orbitrap Spectrometer
     as provided by clause 8 of the Subscription Agreement.

7.2  The parties hereby acknowledge that nothing contained herein shall operate
     so as to bring to an end the continuing obligations of any of them pursuant
     to the Collaboration Agreement or the Contract Manufacturing Agreement.

8.   FURTHER ASSURANCE

8.1  At any time after the date hereof GSL shall, at the request and cost of the
     Purchasers, execute or procure the execution of such documents and do or
     procure the doing of such acts and things as the Purchasers may reasonably
     require for the purpose of vesting the Sale Shares in the Purchasers or its

<PAGE>   8

     nominees and giving to the Purchasers the full benefit of all the
     provisions of this Agreement.

9.   INVALIDITY

9.1  If any provision of this Agreement shall be held to be illegal, void,
     invalid or unenforceable under the laws of any jurisdiction, the legality,
     validity and enforceability of the remainder of this Agreement in that
     jurisdiction shall not be affected, and the legality, validity and
     enforceability of the whole of this Agreement in any other jurisdiction
     shall not be affected.

10.  NOTICES

10.1 Any notice or other communication required to be given under this Agreement
     or in connection with the matters contemplated by it shall, except where
     otherwise specifically provided, be in writing in the English language and
     shall be addressed as provided in clause 10.2 and may be:

     (a)  personally delivered, in which case it shall be deemed to have been
          given upon delivery at the relevant address; or

     (b)  if within the United Kingdom, sent by first class pre-paid post, in
          which case it shall be deemed to have been given two Business Days
          after the date of posting; or

     (c)  if from or to any place outside the United Kingdom, sent by pre-paid
          priority airmail, in which case it shall be deemed to have been given
          seven Business Days after the date of posting; or

     (d)  sent by fax, in which case it shall be deemed to have been given when
          despatched, subject to confirmation or uninterrupted transmission by a
          transmission report provided that any notice despatched by fax after
          17.00 hours (at the place where such fax is to be received) on any day
          shall be deemed to have been received at 08.00 on the next Business
          Day.

10.2 The address and the other details of the parties referred to in clause
          100.1 are, subject to clause 10.3:

     Genomic Solutions Limited
     8 Blackstone Road
     Huntingdon
     Cambridgeshire
     PE18 6EF

     Fax number: 01480 471660

<PAGE>   9

               H D Technologies Limited
               95-98 Atlas House
               Simonsway
               Manchester
               M22 5PP

               Fax number: 0161 499 7603

               cc. General Counsel
               81 Wyman Street
               Post Office Box 9046
               Waltham
               MA 02254-9046
               USA

               Fax number: 00 1 781 622 1283

               Stephen Charles Davis: as set out in Schedule 1

               Andrew David Hoffman: as set out in Schedule 1

          10.3 Any party to this Agreement may notify the other parties of any
               change to its address or other details specified in clause 10.2,
               provided that such notification shall be effective only on the
               date specified in such notice or five Business Days after the
               notice is given, whichever is later.

          11.  ASSIGNMENT

          11.1 No party shall be entitled to assign or transfer its rights and
               obligations under this Agreement (whether in whole or part)
               without the prior consent of the other parties, unless such
               assignment or transfer is to a member of the assigning party's
               Group.

          12.  LAW AND JURISDICTION

          12.1 This Agreement shall be governed by, and construed in accordance
               with, English law.

          12.2 In relation to any legal action or proceedings to enforce this
               Agreement or arising out of or in connection with this Agreement
               ("PROCEEDINGS") each of the parties irrevocably submits to the
               jurisdiction of the English courts and waives any objection to
               proceedings in such courts on the grounds of venue or on the
               grounds that the proceedings have been brought in an inconvenient
               forum.

          IN WITNESS whereof this Agreement has been executed as a deed on the
               day and year first before written.

<PAGE>   10

                                   SCHEDULE 1

                                 The Purchasers

Stephen Charles Davis
8 Flash Lane
Bollington
Macclesfield
Cheshire
SK10 5AQ

Andrew David Hoffman
15 Spath Road
Didsbury
Manchester
M20 2QT

<PAGE>   11

                                   SCHEDULE 2
                                   ----------

THIS AGREEMENT is made on                      2000

BETWEEN:

(1)  GENOMIC SOLUTIONS LIMITED (No 2315315) whose registered office is at 8
     Blackstone Road, Huntingdon, Cambridgeshire, PE18 6EF ("GSL"); and

(2)  H D TECHNOLOGIES LIMITED (No 2916498) whose registered office is at 3
     Chester Road, Neston, South Wirral, Cheshire, L64 9PA ("HDT").

WHEREAS:

(A)  GSL is the registered proprietor of the Patent (as defined below).

(B)  By an agreement dated of even date it was agreed between the parties
     thereto that GSL would grant to HDT a licence under the said Patent and HDT
     would grant to GSL a licence back as herein set forth.

(C)  Accordingly, the parties have now agreed to execute this Agreement.

NOW IT IS HEREBY AGREED as follows:

1.   DEFINITIONS

1.1  this Schedule, unless the context otherwise requires:

     (a)  the following terms shall have the following meanings

          "COPYRIGHT" means all copyright and all rights in databases and
          database rights and rights in the nature of copyright to which either
          party may now be or may subsequently become entitled in or in respect
          of all drawings and other documents, recordings in any form and all
          other materials bearing or embodying any part of the Technical
          Information including without limitation any such materials consisting
          of or containing software or databases;

          "EXCLUSIVE FIELD" means any and all applications and uses including
          without limitation, applications using Tandem Instruments but
          excluding those relating to MALDI-TOF Spectrometry and other
          proteomics applications;

          "FIELD" means the Sole Field and/or the Exclusive Field;

          "GROUP" means either the GSL Group or the HDT Group, according to the
          context;

<PAGE>   12

          "GSL GROUP" means:

          (a)  GSL;

          (b)  any Holding Company of GSL from time to time;

          (c)  any Subsidiary from time to time of such Holding Company; and

          (d)  any Subsidiary from time to time of GSL;

          "GSL IMPROVEMENT" means any improvement, modification or alteration to
          the invention claimed in the Patent made by the GSL Group during the
          Term;

          "HDT GROUP" means:

          (a)  HDT;

          (b)  the ThermoQuest Corporation ("THERMOQUEST");

          (c)  any Holding Company of HDT or ThermoQuest from time to time;

          (d)  any Subsidiary from time to time of such Holding Company; and

          (e)  any Subsidiary from time to time of HDT or ThermoQuest;

          "HOLDING COMPANY" and "SUBSIDIARY" have the meanings given to them in
          section 736 of the Companies Act 1985;

          "INSTRUMENT" means an instrument relating to the Field and which
          incorporates the invention contained in the Patent;

          "LICENCE" means the provisions of this Agreement;

          "MAJOR COUNTRIES" means Japan and the United States of America and
          each of the countries which are signatories to the European Patent
          Convention and "MAJOR COUNTRY" shall mean any of them;

          "MALDI-TOF SPECTROMETRY" means matrix-assisted laser description
          ionisation time-of-flight spectrometry;

          "PATENTS" means:

          (a)  the patent application short particulars whereof are set out in
               Annexure A hereto;

<PAGE>   13

          (b)  all patent applications that have been or may hereafter be filed
               in the Territory by or on behalf of any member of the GSL Group
               which are based on or claim priority from the foregoing patent
               application;

          (c)  all patent applications that have been or may hereafter be filed
               in the Territory by or on behalf of any member of the GSL Group
               for GSL Improvements made to the invention claimed in the patent
               application, short particulars of which are set out in Annexure
               A; and

          (d)  all patents which may be granted pursuant to any of the foregoing
               patent applications in (a), (b) or (c) above;

          "SOLE FIELD" means any and all applications and uses in the field of
          proteomics including without limitation any and all applications and
          uses of Tandem Instruments with a matrix-assisted laser desorption
          ionisation spectrometer but excluding MALDI-TOF Spectrometry;

          "TANDEM INSTRUMENTS" means a mass spectrometer instrument employing
          more than one mass analyser within the same instrument;

          "TECHNICAL INFORMATION" means all identifiable know-how, experience,
          data and all other technical or commercial information relating to the
          Patent whether in human or machine readable form and whether stored
          electronically or otherwise and which might reasonably be of
          commercial interest to either party in connection with the use or
          exploitation of the Patent;

          "TERM" has the meaning set out in clause 6.1;

          "TERRITORY" means the world.;

     (b)  reference to "the parties" or "either party" or similar expression
          shall mean GSL and HDT or either of them.

     (c)  reference to the singular includes a reference to the plural and vice
          versa.

2.   GRANT OF RIGHTS

2.1  GSL hereby grants to HDT an exclusive world-wide licence during the Term
     to:

     (a)  use the Patents and the Copyright and use the Technical Information
          owned or under the control of any member of the GSL Group and use any
          GSL Improvements; and

<PAGE>   14

          (b)  manufacture and sell products made using the Patents, the
               Copyright and using the Technical Information owned or under the
               control of any member of the GSL Group or using any GSL
               Improvements;

          in each case within the scope of the Exclusive Field anywhere in the
          Territory. GSL shall effect the necessary licences or assignments by
          other members of the GSL Group to GSL to enable GSL to grant the
          licence provided in this clause 2.1.

     2.2  GSL hereby grants to HDT a sole world-wide licence during the Term to:

          (a)  use the Patent and the Copyright and use the Technical
               Information owned or under the control of any member of the GSL
               Group and use any GSL Improvements; and

          (b)  manufacture and sell products made using the Patent, the
               Copyright and using the Technical Information owned or under the
               control of any member of the GSL Group and using any GSL
               Improvements;

          in each case within the scope of the Sole Field anywhere in the
          Territory. GSL shall effect the necessary licences or assignments by
          other members of the GSL Group to GSL to enable GSL to grant the
          licence provided in this clause 2.2.

     2.3  The licences granted under clauses 2.1 and 2.2 contain no right to
          grant sublicences save that HDT may grant sublicences to other members
          of the HDT Group only.

     2.4  HDT shall pay to GSL, in a manner requested by GSL, the sum of
          $US20,000 as an advance against future royalties within thirty days of
          completion of the Agreement between Stephen Davis, Andrew Hoffman and
          ThermoQuest or any of its Subsidiaries for the sale and purchase of
          all of the share capital of HDT.

     2.5  Except as provided in clause 2.6, HDT shall pay to GSL a royalty of
          US$2,000 on the eleventh and each subsequent Instrument (but not on
          the first ten Instruments) sold or otherwise supplied for money or
          money's worth by HDT or any other member of the HDT Group,

     2.6  Royalties under clause 2.5 shall be due and payable in each country
          within the Territory in which HDT or any other member of the HDT Group
          shall sell or supply for money or money's worth or manufacture or have
          manufactured Instruments until whichever shall be the later of:

          (a)  the expiry or lapse of all patents applied for or granted
               pursuant to the Patent within such country within the Territory;

          (b)  in respect of such part of the Territory where patents are not
               registered or applied for pursuant to the Patent, or where all
               such patents or patent applications have lapsed or been withdrawn
               or have expired, the expiry of a period of 10 years from the
               first sale or supply for money or

<PAGE>   15

               money's worth by HDT or any other member of the HDT Group of an
               Instrument within such part of the Territory.

     2.7  Payments due under clause 2.5 shall be made within 30 days of the end
          of each calendar quarter in respect of royalties accruing on
          Instruments invoiced in that calendar quarter.

     2.8  Without prejudice to GSL's rights of termination under clause 6.2, if
          any payment or any part thereof is overdue then HDT shall pay interest
          thereon before and after judgment at an annual rate (but with interest
          accruing on a daily basis) at 4 per cent above the base rate from time
          to time of Barclays Bank Plc such interest to run from the date upon
          which payment of such sum became due until payment thereof in full
          together with such interest by HDT.

     2.9  All sums due under this Agreement are exclusive of any Value Added Tax
          which shall be payable in addition and GSL shall, where appropriate,
          promptly provide a Value Added Tax invoice in the correct amount.

     2.10 HDT agrees to keep true and accurate records and books of account
          containing all data necessary for the determination of royalties
          payable under clause 2.5 which records and books of account shall upon
          reasonable notice by GSL be open at all reasonable times during normal
          business hours for inspection by an independent accountant selected by
          GSL and acceptable to HDT (which acceptance shall not be unreasonably
          withheld or delayed) for the purpose of verifying the accuracy of
          HDT's statements hereunder. The accountant may take copies of the
          records and books of account but shall not disclose to GSL any
          information relating to the business or affairs of HDT other than such
          information as properly should have been contained in any statement
          required to be furnished by HDT to GSL. GSL shall be solely
          responsible for the costs of the accountant unless he certifies that
          any reports are inaccurate by more than 5% in which event HDT shall
          promptly reimburse GSL for his costs.

     2.11 HDT shall submit to GSL within 30 days of the end of each calendar
          quarter a statement setting forth with respect to the operations of
          HDT hereunder during that period the quantity of Instruments sold and
          the royalties payable.

     2.12 GSL agrees to maintain confidential all financial information received
          with respect to HDT's operations pursuant to the foregoing clauses
          2.10 and 2.11 and not to use such information for purposes other than
          to verify the amount of any licence fees payable under this Agreement.

     2.13 GSL shall as soon as reasonably possible disclose to HDT any GSL
          Improvements generated during the Term and such GSL Improvements
          shall be licensed to HDT according to the provisions of clauses 2.1
          and 2.2.

     2.14 GSL hereby warrants, represents and undertakes that it is the legal
          and beneficial owner of the Patent, the Copyright and the Technical
          Information and that GSL has not licensed the Patent, the Copyright
          and the Technical

<PAGE>   16

     Information to any other party for use within the Exclusive Field or the
     Sole Field.

2.15 Subject to the provisions of clause 2.16, GSL hereby undertakes not during
     the Term to license the Patent, the Copyright or the Technical Information
     to any other party for use within the Exclusive Field or the Sole Field
     provided that GSL shall itself be entitled to exploit all of the aforesaid
     within the Sole Field within the Territory during the Term.

2.16 If within two years of the date hereof HDT (or another member of the HDT
     Group) has not been able to demonstrate to GSL's satisfaction that HDT (or
     another member of the HDT Group) has a serious intention to develop and
     commercially exploit the intellectual property licensed under clauses 2.1
     and 2.2 then GSL may forthwith by written notice make each of the licences
     granted under clauses 2.1 and 2.2 non-exclusive and GSL shall thereafter be
     free to:

     (a)  itself use and exploit the Patent, the Copyright and the Technical
          Information within the Exclusive Field; and

     (b)  appoint other licensees of the Patent, the Copyright and the
          Technical Information within the Sole Field and the Exclusive Field.

     In such event, HDT's obligation to pay royalties under clause 2.5 shall
     nevertheless continue in full force and effect. For the purpose of this
     clause "serious intention to develop and commercially exploit" shall mean
     having implemented a fully up and running, ongoing development programme
     and having constructed at least one prototype Instrument.

3 LICENCE BACK

3.1  HDT hereby grants to GSL a non-exclusive irrevocable, royalty-free,
     world-wide licence for the Term (with the right to grant sublicences within
     the GSL Group only) to use, exploit (including by manufacturing and selling
     products) or deal in:

     (a)  any improvements made in the field of MALDI-TOF Spectrometry by HDT or
          another member of the HDT Group to the Patent or the Technical
          Information; HDT shall disclose all such improvements to GSL as soon
          as reasonably possible as and when they arise; and

     (b)  any intellectual property in the field of MALDI-TOF Spectrometry owned
          as at the date hereof or subsequently generated by HDT or another
          member of the HDT Group in relation to the Patent or the Technical
          Information; HDT shall disclose all such intellectual property to GSL
          as soon as reasonably possible as and when it arises.

<PAGE>   17

     3.2  HDT undertakes promptly to procure all licences or assignments to HDT
          by other members of the HDT Group necessary for HDT to grant the
          licences required under clause 3.1

     3.3  HDT may forthwith by written notice terminate the licence granted
          under clause 3.1 if GSL uses, exploits or applies the improvements
          and/or the intellectual property licensed in clause 3.1 outside the
          scope of the field of MALDI-TOF Spectrometry. In such event GSL shall
          promptly return to HDT all HDT and HDT Group confidential information
          and all documentation (whether hard copy or electronic) evidencing the
          intellectual property licensed under clause 3.1.

     4.   CONFIDENTIALITY

     4.1  Each party agrees to maintain secret and confidential all confidential
          information obtained from the other both pursuant to this Agreement
          (including any Technical Information which is secret or confidential)
          and prior to and in contemplation of it and all other information that
          it may acquire from the other, to use the same exclusively for the
          purposes of this Agreement, and to disclose the same only to those
          employees, agents, representatives and contractors pursuant to this
          Agreement (if any) to whom and to the extent that such disclosure is
          reasonably necessary for the purposes of this Agreement.

     4.2  The foregoing obligations of clause 4.1 above shall not apply to
          confidential information or other information which:

          (a)  prior to receipt thereof from one party was in the possession of
               the recipient party and at its free disposal;

          (b)  is subsequently disclosed to the recipient party without any
               obligations of confidence by a third party who has not derived it
               directly or indirectly from the disclosing party; or

          (c)  is or becomes generally available to the public through no act or
               default of the recipient party or its agents or employees.

     4.3  The obligation of confidentiality contained in this clause 4 shall
          last for the Term and continue without limitation in time thereafter.

     5.   PATENTS AND OTHER INTELLECTUAL PROPERTY

     5.1  GSL shall at its own cost use reasonable endeavours to diligently
          prosecute to grant all patent applications within the Patent in at
          least the Major Countries and so as to secure the broadest monopoly
          reasonably obtainable consistent with avoiding serious prejudice to
          the validity of such granted patents and to maintain all such patents
          granted in respect of the Patent in force for the full term thereof.
          Notwithstanding the foregoing, GSL shall not be absolutely obliged to
          take such action as may be necessary to defend any claim by any third
          party challenging the validity of the Patent or the Technical
          Information

<PAGE>   18

     Provided Always that in the event that GSL refrains from such action within
     four weeks of a request by HDT to take such action HDT as licensee
     hereunder shall be entitled at its own cost and expense to maintain and
     defend such Patent or Technical Information (insofar as it relates to the
     Field) and in such circumstances GSL will provide HDT with all such advice
     and assistance (subject to reimbursement of its reasonable expenses) as may
     reasonably be required by HDT in connection with the defence of the Patent
     (or the Technical Information). If HDT takes such action, HDT shall bear
     all costs and expenses relating to it and HDT will be entitled to all
     damages and other recoveries made as a result of such action.

5.2  In the event that GSL shall not pursue further any application within the
     Patent or shall not continue to maintain any patent from time to time
     within the Patent, GSL shall notify HDT and shall if so requested promptly
     assign all rights it may have therein to HDT and HDT may elect to take over
     the pursuit of any such application or maintenance of any such granted
     patents and pay for all consequent expenditure itself. If HDT does so elect
     it shall inform GSL of that decision in writing. Thereafter, as long as HDT
     keeps up such pursuit/maintenance (as applicable) HDT shall not be obliged
     to pay to GSL any royalties in respect of Instruments manufactured, sold or
     supplied in the part of the Territory where it has assumed such
     pursuit/maintenance.

5.3  Each party shall notify the other promptly in the event that it becomes
     aware of:

     (a)  any infringement or alleged infringement by any third party of the
          rights in the other party's intellectual property within any part of
          the Territory; or

     (b)  any allegation by any third party that the use and exploitation of the
          other party's intellectual property infringes any intellectual
          property rights of any such third party in any part of the Territory;

     and subsequently supply to the other party such detailed information
     concerning any such infringement, alleged infringement or third party
     allegation as may be available to it and extend such co-operation as the
     other party shall reasonably request (at the other party's request) in
     countering such infringement, alleged infringement or third party
     allegation.

6    TERM AND TERMINATION

6.1  Subject as hereinafter provided in this clause 6.1 and in clause 6.2, the
     Licence shall commence on the date hereof and shall continue in force in
     perpetuity save that:

     (a)  in respect of all patents within the Patents: the Licence shall
          continue in force in respect of each patent within the Patent until
          such patent expires;

<PAGE>   19

          (b)  in respect of all Technical Information licensed under this
               Agreement: the Licence shall continue in force until such
               information is no longer secret or substantial; and

          (c)  in respect of all Copyright which is not secret or substantial:
               the Licence shall continue in force in each country of the
               Territory until expiry of the Copyright in such country.

     6.2  GSL may forthwith by written notice terminate the licence granted
          under clauses 2.1 and 2.2 if:

          (a)  HDT or any sublicensee of HDT uses, exploits or applies the
               Patent, the Technical Information, the Copyright or any GSL
               Improvements outside the scope of the Field. In such event HDT
               shall promptly return to GSL all GSL confidential information and
               all documentation (whether hard copy or digital) evidencing the
               intellectual property licensed under clauses 2.1 and 2.2; or

          (b)  without prejudice to any of its other rights under this Agreement
               any undisputed sum due to GSL under clause 2.5 (including
               interest accrued under clause 2.8) remains unpaid in full 30 days
               after receipt by HDT of written notification that such sum is
               overdue for payment.

     7.   ASSIGNMENT

     7.1  Neither party shall be entitled to assign or transfer its rights and
          obligations under this Agreement (whether in whole or part) without
          the other party's prior consent, unless such assignment or transfer is
          to a member of the assigning party's Group.

     8.   NOTICES

     8.1  All notices required to be served by the parties to this Agreement
          under the terms hereof shall be sufficiently served if despatched by
          first class post or by fax to the address or fax number of the
          recipient party as set out below or such other address or fax number
          as is notified pursuant to this clause 8:

          HD Technologies Limited
          95-98 Atlas House
          Simonsway
          Manchester
          M22 5PP

          Fax: 0161 499 7603

<PAGE>   20

     cc. General Counsel
     81 Wyman Street
     Post Office Box 9046
     Waltham
     MA 02254-9046
     USA

     Fax: 00 1 781 622 1283

     Genomic Solutions Limited
     7 Blackstone Road
     Huntingdon
     Cambridgeshire
     PE18 6EF

     Fax: 01480 471660

     Provided That:

     (a)  if served by facsimile it will be deemed received when sent, subject
          to issue of a valid transmission slip; and

     (b)  if served by first class post it will be deemed received 2 days after
          posting.

9.   CHOICE OF LAW AND JURISDICTION

9.1  Any controversy or claim of whatsoever nature arising out of or relating in
     any manner whatsoever to this Agreement or any breach of any terms of this
     Agreement shall be governed by and construed in accordance with the Laws of
     England.

9.2  Each party hereby irrevocably acknowledges and agrees that the courts of
     England shall have exclusive jurisdiction to resolve any controversy or
     claim of whatsoever nature arising out of or relating in any manner to this
     Agreement any terms of this Agreement or any breach of this Agreement or
     any such terms.

IN WITNESS whereof this Agreement has been executed as a deed on the day and
year first before written.

<PAGE>   21

                                   ANNEXURE A

The following patent application

Filing No:          PCT/GB99/02244
Filing Date:        13 07 1999
Applicant:          Genomic Solutions Limited
Short Title:        Improved Mass Spectrometer
Basic UK App:       9815457.8

<PAGE>   22

                                         /s/ P. Nick King
EXECUTED and delivered as a deed    )   ---------------------------
by GENOMIC SOLUTIONS LIMITED        )           Director
acting by its authorised officers   )   /s/ Paul Dunkley
                                        ---------------------------
                                            Director/Secretary

                                        /s/ Andrew Hoffman
EXECUTED and delivered as a deed    )   ---------------------------
by H D TECHNOLOGIES LIMITED         )             Director
acting by its authorised officers   )   /s/ Steve Davis
                                        ---------------------------
                                             Director/Secretary

<PAGE>   23

                                         /s/ P. Nick King
EXECUTED and delivered as a deed   )    ---------------------------
by GENOMIC SOLUTIONS LIMITED       )              Director
acting by its authorized officers: )     /s/  Paul Dunkley
                                        ---------------------------
                                             Director/Secretary

EXECUTED and delivered as a deed   )
by STEPHEN CHARLES DAVIS           )     /s/ Stephen Davis
in the presence of                 )

EXECUTED and delivered as a deed   )
by ANDREW DAVID HOFFMAN            )     /s/ Andrew David Hoffman
in the presence of:                )

                                         /s/ Andrew David Hoffman
EXECUTED and delivered as a deed   )    ---------------------------
by H D TECHNOLOGIES LIMITED        )              Director
acting by its authorized officers: )     /s/ Stephen Davis
                                        ---------------------------
                                             Director/Secretary

<PAGE>   24

THIS AGREEMENT is made on 25th January, 2000

BETWEEN:

(1)      GENOMIC SOLUTIONS LIMITED (No 2315315) whose registered office
         is at 8 Blackstone Road, Huntingdon, Cambridgeshire, PE18 6EF ("GSL");
         and

(2)      H D TECHNOLOGIES LIMITED (No 2916498) whose registered office is
         at 3 Chester Road, Neston, South Wirral, Cheshire, L64 9PA ("HDT").

WHEREAS:

(A)      GSL is the registered proprietor of the Patent (as defined below).

(B)      By an agreement dated of even date it was agreed between the parties
         thereto that GSL would grant to HDT a licence under the said Patent and
         HDT would grant to GSL a licence back as herein set forth.

(C)      Accordingly, the parties have now agreed to execute this Agreement.

NOW IT IS HEREBY AGREED as follows:

1.       DEFINITIONS

1.1      this Schedule, unless the context otherwise requires:

         (a)     the following terms shall have the following meanings

                 "COPYRIGHT" means all copyright and all rights in databases and
                 database rights and rights in the nature of copyright to which
                 either party may now be or may subsequently become entitled in
                 or in respect of all drawings and other documents, recordings
                 in any form and all other materials bearing or embodying any
                 part of the Technical Information including without limitation
                 any such materials consisting of or containing software or
                 databases;

                 "EXCLUSIVE FIELD" means any and all applications and uses
                 including without limitation, applications using Tandem
                 Instruments but excluding those relating to MALDI-TOF
                 Spectrometry and other proteomics applications;

                 "FIELD" means the Sole Field and/or the Exclusive Field;

                 "GROUP" means either the GSL Group or the HDT Group, according
                 to the context;

<PAGE>   25

                 "GSL GROUP" means:

                 (a)  GSL;

                 (b)  any Holding Company of GSL from time to time;

                 (c)  any Subsidiary from time to time of such Holding Company;
                      and

                 (d)  any Subsidiary from time to time of GSL;

                "GSL IMPROVEMENT" means any improvement, modification or
                alteration to the invention claimed in the Patent made by the
                GSL Group during the Term;

                "HDT GROUP" means:

                 (a)  HDT;

                 (b)  the ThermoQuest Corporation ("THERMOQUEST");

                 (c)  any Holding Company of HDT or ThermoQuest from time to
                      time;

                 (d)  any Subsidiary from time to time of such Holding Company;
                      and

                 (e)  any Subsidiary from time to time of HDT or ThermoQuest;

                "HOLDING COMPANY" and "SUBSIDIARY" have the meanings given to
                them in section 736 of the Companies Act 1985;

                "INSTRUMENT" means an instrument relating to the Field and which
                incorporates the invention contained in the Patent;

                "LICENCE" means the provisions of this Agreement;

                "MAJOR COUNTRIES" means Japan and the United States of America
                and each of the countries which are signatories to the European
                Patent Convention and "MAJOR COUNTRY" shall mean any of them;

                "MALDI-TOF SPECTROMETRY" means matrix-assisted laser description
                ionisation time-of-flight spectrometry;

                "PATENTS" means:

                (a)   the patent application short particulars whereof are set
                      out in Annexure A hereto;

<PAGE>   26

                (b)   all patent applications that have been or may hereafter be
                      filed in the Territory by or on behalf of any member of
                      the GSL Group which are based on or claim priority from
                      the foregoing patent application;

                (c)   all patent applications that have been or may hereafter be
                      filed in the Territory by or on behalf of any member of
                      the GSL Group for GSL Improvements made to the invention
                      claimed in the patent application, short particulars of
                      which are set out in Annexure A; and

                (d)   all patents which may be granted pursuant to any of the
                      foregoing patent applications in (a), (b) or (c) above;

                "SOLE FIELD" means any and all applications and uses in the
                field of proteomics including without limitation any and all
                applications and uses of Tandem Instruments with a matrix-
                assisted laser desorption ionisation spectrometer but excluding
                MALDI-TOF Spectrometry;

                "TANDEM INSTRUMENTS" means a mass spectrometer instrument
                employing more than one mass analyser within the same
                instrument;

                "TECHNICAL INFORMATION" means all identifiable know-how,
                experience, data and all other technical or commercial
                information relating to the Patent whether in human or machine
                readable form and whether stored electronically or otherwise and
                which might reasonably be of commercial interest to either party
                in connection with the use or exploitation of the Patent;

                "TERM" has the meaning set out in clause 6.1;

                "TERRITORY" means the world.;

         (b)    reference to "the parties" or "either party" or similar
                expression shall mean GSL and HDT or either of them.

         (c)    reference to the singular includes a reference to the plural and
                vice versa.

     2.  GRANT OF RIGHTS

     2.1 GSL hereby grants to HDTan exclusive world-wide licence during the
Term to:

         (a)    use the Patents, and the Copyright and use the Technical
                Information owned or under the control of any member of the GSL
                Group and use any GSL Improvements; and

<PAGE>   27
         (b)    manufacture and sell products made using the Patents, the
                Copyright and using the Technical Information owned or under
                the control of any member of the GSL Group or using any GSL
                Improvements;

         in each case within the scope of the Exclusive Field anywhere in the
         Territory. GSL shall effect the necessary licences or assignments by
         other members of the GSL Group to GSL to enable GSL to grant the
         licence provided in this clause 2.1.

2.2      GSL hereby grants to HDT a sole world-wide licence during the Term to:

         (a)      use the Patent and the Copyright and use the Technical
                  Information owned or under the control of any member of the
                  GSL Group and use any GSL Improvements; and

         (b)      manufacture and sell products made using the Patent, the
                  Copyright and using the Technical Information owned or under
                  the control of any member of the GSL Group and using any GSL
                  Improvements;

         in each case within the scope of the Sole Field anywhere in the
         Territory. GSL shall effect the necessary licences or assignments by
         other members of the GSL Group to GSL to enable GSL to grant the
         licence provided in this clause 2.2.

2.3      The licences granted under clauses 2.1 and 2.2 contain no right to
         grant sublicences save that HDT may grant sublicences to other members
         of the HDT Group only.

2.4      HDT shall pay to GSL, in a manner requested by GSL, the sum of
         $US20,000 as an advance against future royalties within thirty days of
         completion of the Agreement between Stephen Davis, Andrew Hoffman and
         ThermoQuest or any of its Subsidiaries for the sale and purchase of all
         of the share capital of HDT.

2.5      Except as provided in clause 2.6, HDT shall pay to GSL a royalty of
         US$2,000 on the eleventh and each subsequent Instrument (but not on the
         first ten Instruments) sold or otherwise supplied for money or money's
         worth by HDT or any other member of the HDT Group.

2.6      Royalties under clause 2.5 shall be due and payable in each country
         within the Territory in which HDT or any other member of the HDT Group
         shall sell or supply for money or money's worth or manufacture or have
         manufactured Instruments until whichever shall be the later of:

         (a)      the expiry or lapse of all patents applied for or granted
                  pursuant to the Patent within such country within the
                  Territory;

         (b)      in respect of such part of the Territory where patents are not
                  registered or applied for pursuant to the Patent, or where all
                  such patents or patent applications have lapsed or been
                  withdrawn or have expired, the expiry of a period of 10 years
                  from the first sale or supply for money or

<PAGE>   28

                   money's worth by HDT or any other member of the HDT Group
                   of an Instrument within such part of the Territory.

2.7      Payments due under clause 2.5 shall be made within 30 days of the end
         of each calendar quarter in respect of royalties accruing on
         Instruments invoiced in that calendar quarter.

2.8      Without prejudice to GSL's rights of termination under clause 6.2, if
         any payment or any part thereof is overdue then HDT shall pay interest
         thereon before and after judgment at an annual rate (but with interest
         accruing on a daily basis) at 4 per cent above the base rate from time
         to time of Barclays Bank Plc such interest to run from the date upon
         which payment of such sum became due until payment thereof in full
         together with such interest by HDT.

2.9      All sums due under this Agreement are exclusive of any Value Added Tax
         which shall be payable in addition and GSL shall, where appropriate,
         promptly provide a Value Added Tax invoice in the correct amount.

2.10     HDT agrees to keep true and accurate records and books of account
         containing all data necessary for the determination of royalties
         payable under clause 2.5 which records and books of account shall upon
         reasonable notice by GSL be open at all reasonable times during normal
         business hours for inspection by an independent accountant selected by
         GSL and acceptable to HDT (which acceptance shall not be unreasonably
         withheld or delayed) for the purpose of verifying the accuracy of HDT's
         statements hereunder. The accountant may take copies of the records and
         books of account but shall not disclose to GSL any information relating
         to the business or affairs of HDT other than such information as
         properly should have been contained in any statement required to be
         furnished by HDT to GSL. GSL shall be solely responsible for the costs
         of the accountant unless he certifies that any reports are inaccurate
         by more than 5% in which event HDT shall promptly reimburse GSL for his
         costs.

2.11     HDT shall submit to GSL within 30 days of the end of each calendar
         quarter a statement setting forth with respect to the operations of HDT
         hereunder during that period the quantity of Instruments sold and the
         royalties payable.

2.12     GSL agrees to maintain confidential all financial information received
         with respect to HDT's operations pursuant to the foregoing clauses 2.10
         and 2.11 and not to use such information for purposes other than to
         verify the amount of any licence fees payable under this Agreement.

2.13     GSL shall as soon as reasonably possible disclose to HDT any GSL
         Improvements generated during the Term and such GSL Improvements shall
         be licensed to HDT according to the provisions of clauses 2.1 and 2.2.

2.14     GSL hereby warrants, represents and undertakes that it is the legal and
         beneficial owner of the Patent, the Copyright and the Technical
         Information and that GSL has not licensed the Patent, the Copyright and
         the Technical

<PAGE>   29

         Information to any other party for use within the Exclusive Field or
         the Sole Field.

2.15     Subject to the provisions of clause 2.16, GSL hereby undertakes not
         during the Term to license the Patent, the Copyright or the Technical
         Information to any other party for use within the Exclusive
         Field or the Sole Field provided that GSL shall itself be entitled to
         exploit all of the aforesaid within the Sole Field within the Territory
         during the Term.

2.16     If within two years of the date hereof HDT (or another member of the
         HDT Group) has not been able to demonstrate to GSL's satisfaction that
         HDT (or another member of the HDT Group) has a serious intention to
         develop and commercially exploit the intellectual property licensed
         under clauses 2.1 and 2.2 then GSL may forthwith by written notice make
         each of the licences granted under clauses 2.1 and 2.2 non-exclusive
         and GSL shall thereafter be free to:

         (a)      itself use and exploit the Patent, the Copyright and the
                  Technical Information within the Exclusive Field; and

         (b)      appoint other licensees of the Patent, the Copyright and the
                  Technical Information within the Sole Field and the Exclusive
                  Field.

         In such event, HDT's obligation to pay royalties under clause 2.5 shall
         nevertheless continue in full force and effect. For the purpose of this
         clause "serious intention to develop and commercially exploit" shall
         mean having implemented a fully up and running, ongoing development
         programme and having constructed at least one prototype Instrument.

3 LICENCE BACK

3.1      HDT hereby grants to GSL a non-exclusive irrevocable, royalty-free,
         world-wide licence for the Term (with the right to grant sublicences
         within the GSL Group only) to use, exploit (including by manufacturing
         and selling products) or deal in:

         (a)      any improvements made in the field of MALDI-TOF Spectrometry
                  by HDT or another member of the HDT Group to the Patent or the
                  Technical Information; HDT shall disclose all such
                  improvements to GSL as soon as reasonably possible as and when
                  they arise; and

         (b)      any intellectual property in the field of MALDI-TOF
                  Spectrometry owned as at the date hereof or subsequently
                  generated by HDT or another member of the HDT Group in
                  relation to the Patent or the Technical Information; HDT shall
                  disclose all such intellectual property to GSL as soon as
                  reasonably possible as and when it arises.

<PAGE>   30

3.2      HDT undertakes promptly to procure all licences or assignments to
         HDT by other members of the HDT Group necessary for HDT to grant the
         licences required under clause 3.1.

3.3      HDT may forthwith by written notice terminate the licence granted under
         clause 3.1 if GSL uses, exploits or applies the improvements and/or the
         intellectual property licensed in clause 3.1 outside the scope of the
         field of MALDI-TOF Spectrometry. In such event GSL shall promptly
         return to HDT all HDT and HDT Group confidential information and all
         documentation (whether hard copy or electronic) evidencing the
         intellectual property licensed under clause 3.1.

4.       CONFIDENTIALITY

4.1      Each party agrees to maintain secret and confidential all confidential
         information obtained from the other both pursuant to this Agreement
         (including any Technical Information which is secret or confidential)
         and prior to and in contemplation of it and all other information that
         it may acquire from the other, to use the same exclusively for the
         purposes of this Agreement, and to disclose the same only to those
         employees, agents, representatives and contractors pursuant to this
         Agreement (if any) to whom and to the extent that such disclosure is
         reasonably necessary for the purposes of this Agreement.

4.2      The foregoing obligations of clause 4.1 above shall not apply to
         confidential information or other information which:

         (a)      prior to receipt thereof from one party was in the possession
                  of the recipient party and at its free disposal;

         (b)      is subsequently disclosed to the recipient party without any
                  obligations of confidence by a third party who has not derived
                  it directly or indirectly from the disclosing party; or

         (c)      is or becomes generally available to the public through no act
                  or default of the recipient party or its agents or employees.

4.3      The obligation of confidentiality contained in this clause 4 shall last
         for the Term and continue without limitation in time thereafter.

5.       PATENTS AND OTHER INTELLECTUAL PROPERTY

5.1      GSL shall at its own cost use reasonable endeavours to diligently
         prosecute to grant all patent applications within the Patent in at
         least the Major Countries and so as to secure the broadest monopoly
         reasonably obtainable consistent with avoiding serious prejudice to the
         validity of such granted patents and to maintain all such patents
         granted in respect of the Patent in force for the full term thereof.
         Notwithstanding the foregoing, GSL shall not be absolutely obliged to
         take such action as may be necessary to defend any claim by any third
         party challenging the validity of the Patent or the Technical
         Information
<PAGE>   31

         Provided Always that in the event that GSL refrains from such action
         within four weeks of a request by HDT to take such action HDT as
         licensee hereunder shall be entitled at its own cost and expense to
         maintain and defend such Patent or Technical Information (insofar as it
         relates to the Field) and in such circumstances GSL will provide HDT
         with all such advice and assistance (subject to reimbursement of its
         reasonable expenses) as may reasonably be required by HDT in connection
         with the defence of the Patent (or the Technical Information). If HDT
         takes such action, HDT shall bear all costs and expenses relating to it
         and HDT will be entitled to all damages and other recoveries made as a
         result of such action.

5.2      In the event that GSL shall not pursue further any application within
         the Patent or shall not continue to maintain any patent from time to
         time within the Patent, GSL shall notify HDT and shall if so requested
         promptly assign all rights it may have therein to HDT and HDT may elect
         to take over the pursuit of any such application or maintenance of any
         such granted patents and pay for all consequent expenditure itself. If
         HDT does so elect it shall inform GSL of that decision in writing.
         Thereafter, as long as HDT keeps up such pursuit/maintenance (as
         applicable) HDT shall not be obliged to pay to GSL any royalties in
         respect of Instruments manufactured, sold or supplied in the part of
         the Territory where it has assumed such pursuit/maintenance.

5.3      Each party shall notify the other promptly in the event that it becomes
         aware of:

         (a)      any infringement or alleged infringement by any third party of
                  the rights in the other party's intellectual property within
                  any part of the Territory; or

         (b)      any allegation by any third party that the use and
                  exploitation of the other party's intellectual property
                  infringes any intellectual property rights of any such third
                  party in any part of the Territory;

         and subsequently supply to the other party such detailed information
         concerning any such infringement, alleged infringement or third party
         allegation as may be available to it and extend such co-operation as
         the other party shall reasonably request (at the other party's request)
         in countering such infringement, alleged infringement or third party
         allegation.

6        TERM AND TERMINATION

6.1      Subject as hereinafter provided in this clause 6.1 and in clause 6.2,
         the Licence shall commence on the date hereof and shall continue in
         force in perpetuity save that:

         (a)      in respect of all patents within the Patents: the Licence
                  shall continue in force in respect of each patent within the
                  Patent until such patent expires;
<PAGE>   32

         (b)      in respect of all Technical Information licensed under this
                  Agreement: the licence shall continue in force until such
                  information is no longer secret or substantial; and

         (c)      in respect of all Copyright which is not secret or
                  substantial: the Licence shall continue in force in each
                  country of the Territory until expiry of the Copyright in such
                  country.

6.2      GSL may forthwith by written notice terminate the licence granted under
         clauses 2.1 and 2.2 if:

         (a)      HDT or any sublicensee of HDT uses, exploits or applies the
                  Patent, the Technical Information, the Copyright or any GSL
                  Improvements outside the scope of the Field. In such event HDT
                  shall promptly return to GSL all GSL confidential information
                  and all documentation (whether hard copy or digital)
                  evidencing the intellectual property licensed under clauses
                  2.1 and 2.2; or

         (b)      without prejudice to any of its other rights under this
                  Agreement any undisputed sum due to GSL under clause 2.5
                  (including interest accrued under clause 2.8) remains unpaid
                  in full 30 days after receipt by HDT of written notification
                  that such sum is overdue for payment.

7.       ASSIGNMENT

7.1      Neither party shall be entitled to assign or transfer its rights and
         obligations under this Agreement (whether in whole or part) without the
         other party's prior consent, unless such assignment or transfer is to a
         member of the assigning party's Group.

8.       NOTICES

8.1      All notices required to be served by the parties to this Agreement
         under the terms hereof shall be sufficiently served if despatched by
         first class post or by fax to the address or fax number of the
         recipient party as set out below or such other address or fax number as
         is notified pursuant to this clause 8:

         HD Technologies Limited
         95-98 Atlas House
         Simonsway
         Manchester
         M22 5PP
         Fax: 0161 499 7603

<PAGE>   33

         cc. General Counsel
         81 Wyman Street
         Post Office Box 9046
         Waltham
         MA 02254-9046
         USA

         Fax: 00 1 781 622 1283

         Genomic Solutions Limited
         7 Blackstone Road
         Huntingdon
         Cambridgeshire
         PE18 6EF

         Fax: 01480 471660

         Provided That:

         (a) if served by facsimile it will be deemed received when sent,
             subject to issue of a valid transmission slip; and

         (b) if served by first class post it will be deemed received 2 days
             after posting.

9.       CHOICE OF LAW AND JURISDICTION

9.1      Any controversy or claim of whatsoever nature arising out of or
         relating in any manner whatsoever to this Agreement or any breach of
         any terms of this Agreement shall be governed by and construed in
         accordance with the Laws of England.

9.2      Each party hereby irrevocably acknowledges and agrees that the courts
         of England shall have exclusive jurisdiction to resolve any controversy
         or claim of whatsoever nature arising out of or relating in any manner
         to this Agreement any terms of this Agreement or any breach of this
         Agreement or any such terms.

IN WITNESS whereof this Agreement has been executed as a deed on the day and
year first before written.

<PAGE>   34

                                   ANNEXURE A

The following patent application

Filing No:                PCT/GB99/02244
Filing Date:              13 07 1999
Applicant:                Genomic Solutions Limited
Short Title:              Improved Mass Spectrometer
Basic UK App:             9815457.8

<PAGE>   35

                                                 /s/ P. Nick King
EXECUTED and delivered as a deed       )         ------------------------
by GENOMIC SOLUTIONS LIMITED           )                 Director
acting by its authorised officers      )         /s/ Paul Dunkley
                                                 ------------------------
                                                    Director/Secretary

                                                 /s/ Andrew Hoffman
EXECUTED and delivered as a deed       )         ------------------------
by H D TECHNOLOGIES LIMITED            )                 Director
acting by its authorised officers      )         /s/ Steve Davis
                                                 ------------------------
                                                    Director/Secretary

<PAGE>   36

                            [THERMOQUEST LETTERHEAD]

Mr N. King
Genomic Solutions Limited
8 Blackstone Road
Huntingdon
Cambridgeshire
PE18 6EF

19 January, 2000

Dear Mr King

COLLABORATION AGREEMENT BETWEEN GENOMIC SOLUTIONS LIMITED AND HEAVY DUTY
TECHNOLOGIES LIMITED DATED 16 APRIL 1998 ("AGREEMENT")

Masslab Limited ("Masslab") is considering purchasing all of the issued share
capital of H.D. Technologies Limited.

Masslab is happy to offer to Genomic Solutions Inc. the comfort that should
Masslab acquire all of the issued share capital of H.D. Technologies Limited,
then:

(1)      Masslab shall and shall procure that H.D Technologies Limited, or any
         Subsidiary (as defined in section 736 of the Companies Act 1985) of
         ThermoQuest Corporation to which the Agreement is assigned or
         transferred will carry out the obligations of H.D. Technologies Limited
         under or pursuant to the Agreement; and

(2)      Dr Stephen Davis and Mr Andrew Hoffman shall be, so long as (a) they
         are employees of ThermoQuest Corporation or any of its Subsidiaries;
         and (b) the Agreement has not been terminated and has not expired; and
         (c) the obligations described at (1) above have not been completed:

         -   at any given point in time employed by ThermoQuest Corporation or
             such of its Subsidiaries which at the same time owns the business
             of H.D. Technologies Limited; and

         -   primarily responsible for the carrying out of the obligations
             described at (1) above.

(3)      This comfort will be given in consideration for Genomic Solutions
         Limited accepting and agreeing that:

         (a)      it irrevocably and absolutely waives all rights and claims
                  which it has or may in future have against H.D. Technologies
                  Limited, in respect of any failure up to the date of this
                  letter by H.D. Technologies Limited to achieve the Milestones
                  (as defined in the Agreement) on the dates specified for such
                  Milestones, including without limitation the right to withhold
                  or not make payments which would be payable save for such
                  failure; and

         (b)      agreeing that the Agreement shall be varied as follows:

                  (i)      in Clause 7 (f) under "Due Date", the following words
                           shall be deleted:

                                    "12 calendar months from Commencement Date"

                           and shall be replaced by the following words:

                                    "31 March 2000".

                  (ii)     adding at the end of Clause 11, the following:

                           "and provided always that this Agreement may be
                           assigned by HDTL to any Subsidiary (as defined in
                           section 736 of the Companies Act 1985) of
<PAGE>   37

                           ThermoQuest Corporation without having first obtained
                           GSL's prior consent or approval in writing".

                  The above variations are to be read together with, and form an
                  integral part of, the Agreement.

                  In the event of any inconsistency between the terms of section
                  (3) of this letter and the Agreement, the terms of section (3)
                  of this letter shall prevail.

This letter is governed by English law and Genomic Solutions Limited and Masslab
Limited hereby submit to the exclusive jurisdiction of the English Courts.

Please confirm your acceptance of the terms of this letter by signing, dating
and returning the enclosed copy of this letter.

Yours sincerely

/s/ Dr W. McKnight

DR W. MCKNIGHT
for and on behalf of:
MASSLAB LIMITED

MR N. KING
Accepted for and on behalf of:
GENOMIC SOLUTIONS LIMITED

/s/ P. Nicholas King
-------------------------------

Date:
     --------------------------

                                       2

<PAGE>   38

                            [THERMOQUEST LETTERHEAD]

Dr J. Williams
Genomic Solutions Inc.
4355 Varsity Drive
Ann Arbor
Michigan 48108
USA

19 January, 2000

Dear Dr Williams

CONTRACT MANUFACTURING AGREEMENT BETWEEN GENOMIC SOLUTIONS INC. AND HEAVY DUTY
TECHNOLOGIES LIMITED DATED 13 JULY 1999 ("AGREEMENT")

Masslab Limited ("Masslab") is considering purchasing all of the issued share
capital of H.D. Technologies Limited.

Masslab is happy to offer to Genomic Solutions Inc. the comfort that should
Masslab acquire all of the issued share capital of H.D. Technologies Limited,
then:

(1)      Masslab shall and shall procure that H.D Technologies Limited, or any
         Subsidiary (as defined in section 736 of the Companies Act 1985) of
         ThermoQuest Corporation to which the Agreement is assigned or
         transferred will carry out the obligations of H.D. Technologies Limited
         under or pursuant to the Agreement; and

(2)      Dr Stephen Davis and Mr Andrew Hoffman shall be, so long as (a) they
         are employees of ThermoQuest Corporation or any of its Subsidiaries;
         and (b) the Agreement has not been terminated and has not expired; and
         (c) the obligations described at (1) above have not been completed:

         -   at any given point in time employed by ThermoQuest Corporation or
             such of its Subsidiaries which at the same time owns the business
             of H.D. Technologies Limited; and

         -   primarily responsible for the carrying out of the obligations
             described at (1) above.

(3)      This comfort will be given in consideration for Genomic Solutions Inc.
         accepting and agreeing that:

         (a)      it did not require delivery of three units of Product (as
                  defined in the Agreement) by December 15 1999 and Genomic
                  Solutions Inc. and waiving irrevocably and absolutely all
                  rights and claims which it have or may in future have against
                  H.D. Technologies Limited, in respect of any failure of H.D.
                  Technologies Limited to deliver three units of Product by
                  December 15 1999; and

         (b)      the Agreement shall be varied as follows:

                  (i)      In Clause 4.1 the following words shall be deleted:

                                    "three units of Product by December 15,
                                    1999"

                           and shall be replaced by the following:

                                    "two units of Product by 30 June, 2000".

                  (ii)     The last sentence of Clause 1.3 shall be deleted and
                           be replaced with the following:

                                    "Notwithstanding the foregoing, for the two
                                    units due by 30 June 2000, the Purchaser
                                    shall advance to the Manufacturer two (2)
                                    separate payments of forty five thousand
                                    (45,000) pounds Sterling, the first by the
                                    end of December 1999 and the second by the
                                    end of January 2000".
<PAGE>   39

                  (iii)    In Clause 11.5, after the words: "...which consent
                           may be withheld for any reason..." the following
                           words shall be added:

                                    "save always that this Agreement may be
                                    assigned by the Manufacturer to any
                                    Subsidiary (as defined in section 736 of the
                                    Companies Act 1985) of ThermoQuest
                                    Corporation without having first obtained
                                    the Purchaser's prior consent or approval in
                                    writing".

                  The above variations are to be read together with, and form an
                  integral part of, the Agreement.

                  In the event of any inconsistency between the terms of section
                  (3) of this letter and the Agreement, the terms of section (3)
                  of this letter shall prevail.

This letter is governed by English law and Genomic Solutions Inc. and Masslab
Limited hereby submit to the exclusive jurisdiction of the English Courts.

Please confirm your acceptance of the terms of this letter by signing, dating
and returning the enclosed copy of this letter.

Yours sincerely

/s/ Dr W. McKnight

DR W. MCKNIGHT
for and on behalf of:
MASSLAB LIMITED

DR J. WILLIAMS
Accepted for and on behalf of:
GENOMIC SOLUTIONS INC.

/S/ Dr J. Williams

---------------------------------

Date:
     ----------------------------

<PAGE>   40
[GENOMIC SOLUTIONS LOGO]

The Directors
HD Technologies Limited
Atlas House
Simonsway
Manchester
M22 5P

                                                              25th January 2000

Dear Sirs

Further to disposal of our shareholding in the Company and in accordance with
the provisions of the Articles of Association of the Company we hereby give you
notice that Mr P N King is hereby removed as the Nominated Director as such term
is defined in a Subscription Agreement dated 16 April 1998 and made between our
Company (1), Genomic Solutions Inc (2), the Company (3) and we hereby
acknowledge that the Company has no further liability in respect of the
Nominated Director.

Yours faithfully

/s/ Paul Dunkley

For and on behalf of
Genomic Solutions Limited

                       [GENOMIC SOLUTIONS LTD LETTERHEAD]

<PAGE>   41

                                                                            288b
[BOOKS ON SCREEN GRAPHIC(TM)]

Please complete in typescript,
or in bold black capitals.

CHFP021
                                  RESIGNATION OF DIRECTOR OR SECRETARY
                                  (NOT FOR APPOINTMENT (USE FORM 288A) OR CHANGE
                                       OF PARTICULARS (USE FORM 288C))

                     COMPANY NUMBER    2916498

               COMPANY NAME IN FULL    H D TECHNOLOGIES LIMITED

RESIGNATION                            Day   Month    Year
FORM            DATE OF RESIGNATION    25     01      2000

            RESIGNATION AS DIRECTOR    X   as secretary [ ]  Please mark the
                                                             appropriate box. If
                                                             resignation is as a
                                                             director and
                                                             secretary mark both
                                                             boxes.

               NAME   *Style/Title              *Honours etc __________________

Please insert
details as              Forename(s)    PAUL NICHOLAS
previously
notified to                 Surname    KING
Companies House.
                                       Day   Month    Year

                     *Date of Birth    05    06       1939

   If cessation is other than
   resignation, please state reason  __________________________________________

                                  A SERVING DIRECTOR, SECRETARY ETC MUST SIGN
                                  THE FORM BELOW.

                                  SIGNED /s/ Steven Davis         DATE  25/1/00

                                  (**serving director/secretary/administrator/
                                  administrative receiver/receiver
*  Voluntary details.             manager/receiver)
+  Directors only.
** Delete as appropriate

Please give the name, address,    WARNER CRANSTON, PICKFORDS WHARF, CLINK STREET
telephone number and, if          LONDON, SE1 9DG
available, a DX number and        REF: AYD             Tel 0171 403 2900
Exchange of the person Companies  DX number 39904  DX EXCHANGE   LONDON BRIDGE 5
House should contact if there
is any query.

Companies House receipt date      When you have completed and signed the form
barcode                           please send it to the Registrar of Companies
                                  at:
                                  COMPANIES HOUSE, CROWN WAY, CARDIFF, CF43UZ
                                  DX 3305O CARDIFF
                                  for companies registered in England and Wales
                                  OR
                                  COMPANIES HOUSE, 37 CASTLE TERRACE, EDINBURGH,
                                  EH1 2EB

<PAGE>   42
                 [BEDFORD CORPORATE BUSINESS CENTRE LETTERHEAD]

                                                                [NATWEST LOGO]

20 December 1999

To: Jason Williams                           FROM: Sue Glass
<TABLE>
<S>                                          <C>            <C>                           <C>
______________________________________       __________________________________________________________________

Re: Genomic Solutions Limited
_______________________________________________________________________________________________________________

Number of sheets (including this sheet):    1               THIS MESSAGE IS SENT          UNAUTHORISED
                                                            IN CONFIDENCE FOR             RECIPIENTS MUST
                                                            THE ADDRESSEE ONLY.           PRESERVE THIS
                                                            THE CONTENTS ARE NOT          CONFIDENTIALITY AND
                                                            TO BE DISCLOSED TO            SHOULD PLEASE ADVISE
                                                            ANYONE OTHER THAN             THE SENDER
                                                            THE ADDRESSEE.                IMMEDIATELY OF ANY
                                                                                          ERROR IN
                                                                                          TRANSMISSION.

</TABLE>

Further to my telephone conversation with Andrea Goodman's secretary on 10th
December 1999 1 can advise you that having checked with our Securities Centre in
Nottingham, there are no shares held under the Mortgage Debenture dated
24.11.99.

/s/ S Glass
S Glass
Corporate Officer

<PAGE>   43
                                 FORM OF RELEASE

Debenture dated 24 November 1999 ("the Debenture") and made between Genomic
Solutions Limited (1) ("the Company") and White Pines Management LLC as
Security Trustee for and on behalf of the Lenders (2) pursuant to a Business
Loan Agreement dated 23 April 1999.

WHEREAS

1.       By Clause 2 of the Debenture a fixed charge was created over the
         stocks, shares and other securities of the Company in favour of the
         Security Trustee on behalf of the Lenders;

2.       The Company owns 300 Convertible Redeemable Preference Shares of Pound
         Sterling each in the capitol of HD Technologies Limited ("HDT") a
         private company incorporated in the United Kingdom;

3.       The Company desires to dispose of the whole of its shareholding in
         HDT and has requested a release of the said shareholding from the
         fixed charge created by the Debenture

the Security Trustee on behalf of the Lenders hereby releases the shareholding
in HDT charged by the Debenture from all moneys secured by and from all claims
and demands under the Debenture

SIGNED AND DELIVERED
BY /s/  Frederick L. Yocum
   ---------------------------------------
     Frederick L. Yocum, Chairman
FOR AND ON BEHALF OF WHITE PINES MANAGEMENT LLC

<PAGE>   44
TRANSFER
FORM

(TRANSFER BY             (Above this line for Registrars only)
COMPANY)
<TABLE>
<S><C>

                                                       Certificate lodged with the Registrar

Consideration Money  $300,000                    (For completion by the Registrar/Stock Exchange)

NAME OF UNDERTAKING.               H. D. TECHNOLOGIES LIMITED (No. 2916498)

DESCRIPTION OF SECURITY.           Convertible Redeemable Preference Shares of Pound Sterling 1.00

NUMBER OR AMOUNT OF SHARES,         Words                         Figures
STOCK OR OTHER SECURITY AND,       One hundred and fifty
IN FIGURES COLUMN ONLY,                                          (150     units of Pound Sterling l.00)
NUMBER AND DENOMINATION
OF UNITS, IF ANY.

NAME AND ADDRESS OF                In the name(s) of
REGISTERED HOLDER SHOULD BE        GENOMIC SOLUTIONS LIMITED (No. 2315315)
GIVEN IN FULL.                     R/O 8 Blackstone Road
                                   Huntingdon
                                   Cambs
                                   PE18 6EF

We hereby transfer the above security out of the name(s) aforesaid to the          Stamp of Selling Broker(s) or, for transactions
person(s) named below.                                                             which are not stock exchange transactions of
                                                                                   Agent(s), if any, acting
                                                                                   for the Transferor(s)

Signed by    GENOMIC SOLUTIONS LIMITED
           ...............................................

 .........................................................

acting by:               /s/ P. Nicholas King
 ......................................................... Director
                         /s/ Paul Dunkley
 ......................................................... Director/Secretary
                                                           (DELETE AS APPROPRIATE) Date   25/1/00
                                                                                          ......................................
</TABLE>

FULL NAME(S). FULL POSTAL                    STEPHEN CHARLES DAVIS
ADDRESS(ES)(INCLUDING COUNTY                 8 Flash Lane
OR, IF APPLICABLE, POSTAL                    Bollington
DISTRICT NUMBER) OF THE                      Macclesfield
PERSON(S) TO WHOM THE                        Cheshire
SECURITY IS TRANSFERRED.                     SK10 5AQ

PLEASE STATE TITLE, IF ANY, OR
WHETHER MR. MRS. OR MISS.

PLEASE COMPLETE IN TYPE
OR IN BLOCK CAPITALS.

I/We request that such entries be made in the register as are necessary to give
effect to this transfer.

 STAMP OF BUYING BROKER(S) (IF ANY).           STAMP OR NAME AND ADDRESS OF
                                                  PERSON LODGING THIS FORM
                                                     (IF OTHER THAN THE
                                                     BUYING BROKER(S)).
<PAGE>   45

TRANSFER
FORM

(TRANSFER BY             (Above this line for Registrars only)
COMPANY)
<TABLE>
<S><C>

                                                       Certificate lodged with the Registrar

Consideration Money  $300,000                    (For completion by the Registrar/Stock Exchange)

NAME OF UNDERTAKING.               H. D. TECHNOLOGIES LIMITED (No. 2916498)

DESCRIPTION OF SECURITY.           Convertible Redeemable Preference Shares of Pound Sterling 1.00

NUMBER OR AMOUNT OF SHARES,         Words                         Figures
STOCK OR OTHER SECURITY AND,       One hundred and fifty
IN FIGURES COLUMN ONLY,                                           (150     units of Pound Sterling l.00)
NUMBER AND DENOMINATION
OF UNITS, IF ANY.

NAME AND ADDRESS OF                In the name(s) of
REGISTERED HOLDER SHOULD BE        GENOMIC SOLUTIONS LIMITED (No. 2315315)
GIVEN IN FULL.                     R/O 8 Blackstone Road
                                   Huntingdon
                                   Cambs
                                   PE18 6EF

We hereby transfer the above security out of the name(s) aforesaid to the          Stamp of Selling Broker(s) or, for transactions
person(s) named below.                                                             which are not stock exchange transactions of
                                                                                   Agent(s), if any, acting
                                                                                   for the Transferor(s)

Signed by    GENOMIC SOLUTIONS LIMITED
           ...............................................

 .........................................................

acting by:               /s/ P. Nicholas King
 ......................................................... Director
                         /s/ Paul Dunkley
 ......................................................... Director/Secretary
                                                           (DELETE AS APPROPRIATE) Date   25/1/00
                                                                                          ......................................
</TABLE>

FULL NAME(S). FULL POSTAL                    ANDREW DAVID HOFFMAN
ADDRESS(ES)(INCLUDING COUNTY                 15 Spath Road
OR, IF APPLICABLE, POSTAL                    Didsbury
DISTRICT NUMBER) OF THE                      Manchester
PERSON(S) TO WHOM THE                        M20 2Q1
SECURITY IS TRANSFERRED.

PLEASE STATE TITLE, IF ANY, OR
WHETHER MR. MRS. OR MISS.

PLEASE COMPLETE IN TYPE
OR IN BLOCK CAPITALS.

I/We request that such entries be made in the register as are necessary to give
effect to this transfer.

 STAMP OF BUYING BROKER(S) (IF ANY).           STAMP OR NAME AND ADDRESS OF
                                                  PERSON LODGING THIS FORM
                                                     (IF OTHER THAN THE
                                                     BUYING BROKER(S)).

<PAGE>   46

                        CONTRACT MANUFACTURING AGREEMENT

     This contract manufacturing agreement (the "Agreement") is made as of this
13th day of July, 1999, by and between HD Technologies, Ltd. (the
"Manufacturer") with offices at 95-98 Atlas House, Simonsway, Manchester M22
5PP, England and Genomic Solutions Inc., a Delaware corporation with offices at
4355 Varsity Drive, Ann Arbor, Michigan 48108 (the "Purchaser").

     WHEREAS, the manufacturer develops and manufactures mass spectrometers;

     WHEREAS, the Purchaser and Manufacturer have entered into an agreement
whereby the Manufacturer is designing and developing a MALDI-TOF mass
spectrometer (the "Product") for the Purchaser;

     WHEREAS, the Purchaser desires to have the Manufacturer manufacture the
Product, and the Manufacturer desires to manufacture and sell the Product to
the Purchaser;

     NOW, THEREFORE, in consideration of the premises and the mutual agreements
and covenants hereinafter set forth, the parties hereto agree as follows:

          1. MANUFACTURE AND SALE OF THE PRODUCT.

               1.1 General. Subject to the terms and conditions of this
Agreement, the Manufacturer shall manufacture and test the Product for the
Purchaser in accordance with the attached product specifications (the "Product
Specifications") and this Agreement. The Purchaser shall purchase, accept
delivery of and pay for all such ordered Product which the Manufacturer shall so
manufacture and deliver to the Purchaser in accordance with the requirements
for manufacture and delivery of Product in the applicable Purchase Order and
this Agreement.

               1.2 Changes to Specifications. If the Purchaser wishes to change
the Product Specifications used to manufacture the Product or any part thereof,
the Purchaser shall notify the Manufacturer in writing and the Manufacturer
shall provide a quote for additional design work and manufacturing required to
modify the existing Product for the production of Product according to the
amended Product Specifications. The Manufacturer shall not be obliged to
commence the additional work required until the additional price for such work
and terms of payment thereof have been agreed in writing by both parties.

               1.3 Raw Materials. The Manufacturer shall order and purchase
all raw materials for the manufacture of the Product in an expeditious manner
after the receipt of a Purchase Order from Purchaser. Purchaser shall
provide Manufacture a cash advance of forty five thousand (45,000) pounds
Sterling to cover the raw material costs for each unit of Product ordered on
the Purchase Order within thirty days of submitting the Purchase Order to the
Manufacturer. Notwithstanding the forgoing, for the next three

                                       1

<PAGE>   47

units, the Purchaser shall advance to the Manufacturer three (3) separate
payments of forty five thousand (45,000) pounds Sterling each by the end of
July, August and September of 1999.

     2. ROLLING FORECAST. The Purchaser's estimate of its requirement for the
Product during the twelve months following the Effective Date (as hereinafter
defined) is set forth in Exhibit B hereto. The Purchaser shall thereafter
provide to the Manufacturer a forecast covering its requirements for Products to
be delivered during each subsequent twelve (12) month period. The parties
acknowledge and agree that the forecasts provided pursuant to this Section 2 are
solely intended to aid the Manufacturer in marking preparations to timely
provide the Purchaser with the ordered quantity of Products.

     3. RELATIONSHIP OF PARTIES. This Agreement shall not constitute either
party the agent or legal representative of the other party for any purpose
whatsoever, and neither party shall hold itself out as an agent of the other
party. This Agreement creates no relationship of joint venturers, partners,
associates, employment or principal and agent between the parties, and both
parties are acting as independent contractors. Neither party is granted herein
any right or authority to, and shall not attempt to, assume or create any
obligation of responsibility or make any representation for or on behalf of
the other party.

     4. TERMS OF PURCHASE ORDERS AND SALES.

                 4.1  Terms to Govern. This Agreement shall govern all orders
for Product by the Purchaser and sales of Product by the Manufacturer to the
Purchaser. Any different, conflicting or additional terms (other than terms as
to quantities and proposed delivery dates) in any Purchaser Order or other
writing from the Purchaser shall be of no force or effect unless they shall
constitute a waiver, modification or amendment of this agreement duly made in
accordance with Section 11.4. Each Purchase Order shall specify a quantity and
delivery date and shall be faxed or sent by overnight mail to the Manufacturer
not less than 18 weeks prior to the requested date of delivery. Notwithstanding
the foregoing, the Manufacturer shall make a reasonable best effort to deliver
three units of Product by December 15, 1999.

                 4.2  Purchase Orders. The Purchaser shall forward all Purchase
Orders to the Manufacturer at its office in Manchester, England. A Purchase
Order shall be deemed accepted if not rejected within five (5) business days
after it is sent by the Purchaser.

                  4.3  Shipment, Delivery and Title. All products will be
tendered and shipped F.O.B. the Manufacturer's factory.  The Purchaser will
select the method of delivery and carrier and pay the cost thereof.  The
Manufacturer will not be deemed to assume any liability in connection with any
shipment because of the selection of a carrier. Title and risk of loss or damage
to each of the Products will pass to the Purchaser when delivery is made to the
possession of a carrier or the Purchaser, whichever occurs first. Claims in
relation to Product damaged in transit shall be reported by the Purchaser to the
carrier, if any, upon the receipt of the Product by the Purchaser.
Nothwithstanding the foregoing, Manufacturer shall be responsible for properly
packaging and crating the

                                       2
<PAGE>   48

Product for shipment.

                 4.4  Price. The price to be paid for each unit of Product by
the Purchaser to the Manufacturer shall be sixty five thousand (65,000) pounds
Sterling. This price shall be offset by any advances provides to Manufacturer
for the purchase of raw materials. Nothwithstanding the foregoing, both
parties agree the intent of this Agreement is for the Purchaser to pay the
Manufacturer a fee of twenty thousand (20,000) pound Sterling for the
manufacture and test of each unit of Product. Therefore, based on current
estimates of 45,000 pounds per unit for raw material costs, the price at which
Manufacturer will sell product to Purchaser (hereafter the "Transfer Price")
has been preliminarily set at 65,000 pounds. Both parties agree to adjust the
Transfer Price as necessary to maintain the fee per unit paid by the Purchaser
to the Manufacturer for manufacture and test at 20,000 pounds Sterling.

                 4.5  Terms of Payment. Terms of payment for Products will be
upon receipt of Product and the invoice from the Manufacturer by the
Purchaser.

          5. WARRANTIES, TECHNICAL SUPPORT AND TRAINING.

               5.1 Limited Warranty. The Manufacturer warrants to the Purchaser
that each Product manufactured and tested by it shall be free from defects in
workmanship and materials in normal use and service for a period of thirteen
(13) months from the date of delivery to the Purchaser. Manufacturer further
warrants that each unit of Product shall be manufactured substantially in
accordance with the Manufacturer's customary procedures for such manufacture and
the applicable Product Specification. If any Product covered by this warranty
should cease to operate within Product Specifications within the warranty period
set forth above, then Manufacturer shall repair or replace any defective part
and provide technical advise and assistance to representatives of Purchaser or
Purchaser's customer via phone, fax, or e-mail, or in person at the
Manufacturer's offices at no charge to the Purchaser. The foregoing
notwithstanding, the Manufacturer will not be responsible for damage to any
product resulting from misuse, negligence or accident or resulting from repairs
or alterations made by any person or firm other than the Manufacturer or a
trained service representative of the Purchaser.

                 5.2  Training. Manufacturer agrees to provide up to three (3)
weeks of technical and service training for up to four (4) representatives of
the Purchaser at the Manufacturer's offices. All travel, lodging, and related
costs shall be born by the Purchaser.

          6. INTENTIONALLY OMITTED

          7. TERM. This Agreement shall become effective on the date hereof (the
"Effective Date") and shall continue for a term of three (3) years, unless
terminated prior to the expiration of this term in accordance with this
Agreement. This Agreement shall automatically renew for successive three (3)
year periods unless terminated in accord with paragraph 8.1.

                                        3

<PAGE>   49

          8. TERMINATION OF AGREEMENT.

                 8.1  Termination. The Purchaser and the Manufacturer shall
each have the right to terminate this Agreement upon the giving of at least
twelve (12) months prior written notice to the other party. In the event of any
termination of this Agreement, the Manufacturer shall return to the Purchaser
all unconsumed raw materials, all finished Product, and all designs, drawings,
notes, technical documentation or other supporting documentation related to the
design, development, manufacture or testing of the Product. Purchaser shall pay
within thirty (30) days all monies owed Manufacture for invoices received by
the Purchaser or labor related to work in progress for the Product.

                 8.2  Bankruptcy, etc. Either party upon written notice to the
other party may terminate this Agreement at any time in the event the other
party shall make any assignment or trust mortgage for the benefit of its
creditors, or shall file a voluntary petition under the bankruptcy,
reorganization, insolvency, or similar laws of any jurisdiction to which it is
subject, or shall suffer an involuntary petition under such laws to be filed
against it, or shall be adjudicated bankrupt or insolvent, or have an order for
relief in bankruptcy entered concerning it, under the laws of any jurisdiction
to which it is subject.

         9.  NOTICES. Any Notice or other communication in connection with this
Agreement shall be in writing and shall be deemed to be duly delivered if
addressed as provided below and if sent by certified or registered air mail,
postage prepaid, return receipt requested, or by Federal Express or other
express courier service, or by hand delivery, addressed as follows:

          (a) If to the Manufacturer:

                                        HD Technologies Ltd.
                                        95-98 Atlas House,
                                        Simonsway, Manchester M22 5PP
                                        England
                                        Fax: (+44) 161-499-7603
                                        Attention: Stephen C. Davis

          (b) If to the Purchaser:

                                        Genomic Solutions Inc.
                                        4355 Varsity Drive
                                        Ann Arbor, Michigan 48108
                                        Fax: 734-975-4808
                                        Attention: Jeffrey Williams

Or to such other address as the addressee shall have specified in a notice
actually received by the addressor.

         10. LICENSE AND INTELLECTUAL PROPERTY.

                                        4

<PAGE>   50

               10.1  License Grant to the Manufacturer. The Purchaser grants to
the Manufacturer a non-exclusive, royalty-free license to use the Purchaser's
trade marks in relation to the Products and all copyrights, patents, patent
applications, know-how, design rights, trade secrets, confidential information,
proprietary information and other rights (together "Proprietary Information")
necessary for the manufacture and testing of the Products. Use of Purchaser's
Proprietary Information shall be limited to the manufacturing of Products for
the Purchaser.

               10.2  Confidentiality. In, order to facilitate the purpose of
this Agreement, either party (the "Disclosing Party") may, but shall not be
obligated to, disclose certain confidential information to the other party (the
"Receiving Party"). The information may be disclosed orally, in writing, on
film, on magnetic media, or in some other form (the "Information").
Information may include, but is not limited to, some or all of the following:
technical specifications, computer programming techniques, software,
documentation, product plans, business plans, customer lists and information,
and financial, marketing or sales data. Dissemination of the Information by the
Receiving Party shall be limited to the Receiving Party's employees who have a
need to know and who shall be notified of the provisions of this Agreement. The
foregoing notwithstanding, information will not constitute Information, and the
Receiving Party will have no obligation to the Disclosing Party with respect to
such information, if:

(a)  Such information is or becomes publicly known or otherwise enters the
     public domain through no wrongful act of the Receiving Party;

(b)  Such information is received by the Receiving Party from a third party
     which has no obligation to the Disclosing Party to maintain it in
     confidence;

(c)  Such information is required to be disclosed by law or any legal order.

               10.3 No Other Licenses. This Agreement shall not be construed to
grant any license to either Party to use any trademark in any manner or to grant
any other licenses between the parties except that license granted in Section
10.1 hereof.

     11.  GENERAL.

               11.1 Survival of Provisions. The provisions of Section 5, 6, 10.2
and this Section 11.1 shall survive the expiration or earlier termination of
this Agreement for any reason.

               11.2 Prior Agreements. This Agreement (including, without
limitation, the Exhibits hereto) contains the entire agreement between the
parties concerning the subject hereof and supersedes all prior agreements and
understandings, written or oral, between them concerning such subject matter.

               11.3 Non-Waiver and Amendment. This Agreement and the warranties,
representations and agreements contained herein may not be waived, modified or
amended, in whole or in part, except by written agreement executed by authorized
officers of the two parties, and no course of dealing or failure or delay shall
constitute a

                                       5
<PAGE>   51

waiver hereunder.

               11.4 Severability. If any provision of this Agreement or any part
thereof shall be found to be invalid, illegal or otherwise unenforceable by a
court of competent jurisdiction, such provision shall to such extent be deemed
null and void and severed from this Agreement, and the remainder of the
Agreement shall remain in full force and effect.

               11.5 Assignment and Benefits. Neither this Agreement nor any
interest in it shall be assigned directly or indirectly by either party without
the prior written consent of the other party, which consent may be withheld for
any reason. This Agreement shall be binding upon, and inure to the benefit of,
the parties hereto and their respective legal representatives, successors and
permitted assigns.

               IN WITNESS WHEREOF, the parties hereto have entered into this
Agreement as a contract under seal as of the date first above written.

The Purchaser:                                    The Manufacturer:

By: /s/ Jeffery S. Williams                       By:  /s/ Steven Davis
   ---------------------------------                   -------------------------
   Title: President & CEO                              Title  Director
   Date:  July 19, 1999                                Date:  July 13, 1999

                                       6

<PAGE>   52

                                    Exhibit A
                             Product Specifications

OVERALL DIMENSIONS:                1845 mm wide x 760 mm deep x 1295 mm High
                                   free standing unit

MASS RESOLUTION:                   >15000 (FWHM) detector 3, Neurotensin

SENSITIVITY:                       10 femtomoles Neurotensin, gives S/N > 20:1

MASS ACCURACY:                     +/- 10 ppm (Av 6 measurements) at m/z -1000

AUTO LOADER:                       5 sample slide capacity cassette mechanism
                                   with loading robot arm

                                       7

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