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                                                                    Exhibit 10.7

[CELLOMICS LOGO]

November 9, 1998

Michael A. Nemzek
70 Lake View Ave.
Cambridge, MA 02138

Dear Mike:

We are pleased to offer you the position of Senior Vice President for Sales and
Marketing for Cellomics, Inc. This position is an officer of the corporation. In
this capacity, you will be reporting to the CEO and will assume responsibility
for:

         (a)      Developing a sales and marketing plan for all Cellomics, Inc.
                  products based on the strategic business plan developed with
                  the CEO and other senior management;
         (b)      Working with the CEO and other senior management in
                  negotiating business deals with pharmaceutical companies;
         (c)      Preparing revenue projections based on business plan;
         (d)      Coordinating the strategic marketing and sales plan with Carl
                  Zeiss, worldwide; and
         (e)      Managing the sales and marketing program including the
                  relationship with Carl Zeiss.

Your starting salary will be $14,167.00 per month, subject to annual increases
as approved by the Board of Directors. In addition to your salary, you will be
eligible to receive an annual performance bonus of up to 35 percent of your base
salary, subject to the review and approval of the Board of Directors. The
performance bonus will be based on attaining the following goals during your
first year of employment:

         (a)      Meeting revenue projections that are mutually defined by
                  January 15, 1999;
         (b)      Successfully launching the ArrayScan(TM) II System for broad
                  sales;

                  635 William Pitt Way o Pittsburgh, PA 15238
                   Phone (412) 826-3600 o Fax (412) 826-3850

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         (c)      Successfully launching 4 screening kits;
         (d)      Successfully launching the ArrayScan(TM) III (ArrayScan
                  Kinetic Module) manufactured by Carl Zeiss for Cellomics, Inc.
                  as an OEM product;
         (e)      Successfully launching the Integrated Drug Discovery Platform
                  manufactured by Carl Zeiss in North America;
         (f)      Successfully launching the initial version of the
                  Cellomics(TM) Database and the Cellomics Screen and Cellomics
                  Discovery informatics products.

To the extent that the above goals are attained in part, a pro rata bonus will
be paid. In subsequent years, the annual bonus will be subject to mutually
agreed-upon goals.

In addition, your employment will include the standard benefits package
available to all Cellomics full-time employees, including full coverage of
company-paid health care (medical and dental), three weeks paid-time-off per
year, paid holidays, and participation in the 401k retirement plan.

In connection with your employment, you will be granted an option to purchase
30,000 shares of Common Stock of the Company at an exercise price of $0.56 per
share. Twenty-five percent (25%) of the shares subject to such option will vest
on the anniversary date of the grant on an annual basis over four years from the
date of grant. An additional option to purchase 5,000 share of Common Stock will
be available as part of the performance bonus described above. Successful
completion of the performance goals will result in the granting of an option to
purchase these shares at an exercise price of $0.56. These additional shares
will vest under the same terms as the original options starting with the date of
hire.

The Company is prepared to offer you assistance for expenses related to your
move at an amount of $50,000.00. This will be in the form of a lump sum. This
lump sum payment is based on your employment for at least one year. You will be
required to repay the Company the total amount if you leave on your own accord
before the end of one year. In addition, the Company will pay for up to 2 round
trips for you and your spouse to visit the Pittsburgh area. This offer is
subject to submission of an I-9 form and satisfactory documentation with respect
to your identification and right to work in the United States no later than
three Pittsburgh days after your employment begins.

As a Cellomics employee, you will be expected to abide by company rules and
regulations. You will specifically be required to sign an acknowledgment that
you have read and understand the company rules of conduct, which will be
included in a handbook which the company will soon complete and distribute. You
will be expected to sign and comply with a proprietary information and
nondisclosure agreement which requires,

         Cellomics, Inc. o 635 William Pitt Way o Pittsburgh, PA 15238
                   Phone (412) 826-3600 o Fax (412) 826-3850

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among other provisions, the assignment of patent rights to any invention made
during your employment at Cellomics, Inc. and nondisclosure of proprietary
information.

As an employee, you may terminate your employment at any time and for any reason
whatsoever with notice to Cellomics, Inc. We request that, in the event of
resignation, you give the company at least two weeks notice. Similarly,
Cellomics, Inc. may terminate your employment at anytime and for any reason
whatsoever, with or without cause. In the event your employment with the Company
is terminated for any reason other than for cause, you will receive salary
continuation and benefits for a period of time ending on the earlier of six
months from termination or until you begin other full time employment. This
severance payment will be contingent on your agreement to not be employed by a
company competing with Cellomics, Inc. within one year of your termination date.

If you wish to accept employment with Cellomics, Inc. under the terms set out
above, please sign and date this letter, and return it to me by November 23,
1998. If you accept our offer, we would like you to start on or before December
7, 1998.

I am personally enthusiastic about you joining Cellomics and helping to build an
exciting company. I look forward to a favorable reply.

Sincerely,

/s/ D. Lansing Taylor
------------------------------
D. Lansing Taylor, Ph.D.
President & CEO

Enclosure(s)

Accepted:

/s/ Michael A. Nemzek
------------------------------
Michael A. Nemzek

November 12, 1998
------------------------------
Dated

          Celomics, Inc. o 635 William Pitt Way o Pittsburgh, PA 15238
                   Phone (412) 826-3600 o Fax (412) 826-3850<PAGE>   1

                                                                    Exhibit 10.8

[CELLOMICS LOGO]

October 12, 1998

Alan W. Seadler, Ph.D.
RD2 Box 159
Export, PA 15632

Dear Alan:

We are pleased to offer you the position of Vice President of Screening Kit
Manufacturing for Cellomics, Inc. In this capacity, you will assume
responsibility for:

         (a)      Operations of the screening kit manufacturing program;

         (b)      Development of new screening kit prototypes working in
                  collaboration with the VP of Biomolecular Assay Technologies;

         (c)      Identification of screening kit components and negotiations
                  for access in collaboration with the Director of Reagent and
                  Screen Business Development;

         (d)      Commercial release of screening kits in collaboration with the
                  VP of Sales and marketing; and

         (e)      Working with the senior management to build the strategic
                  position and value of the Company; and

Your starting salary will be $8,334.00 per month. In addition to your salary,
you will be eligible to receive a performance bonus of up to 20 percent of your
base salary, subject to the review and approval of the Board of Directors. The
performance bonus will be based on attaining the following goals during your
first year of employment:

         (a)      Completing 6 validated screening kits for High Throughput
                  Screens (HTS), High Content Screens (HCS), or a combination of
                  HTS and HCS.

         (b)      Design and implementation of the board approved screening kit
                  manufacturing plan and facilities;

         (c)      Commercial release of at least 4 screening kits

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In addition, your employment will include the standard benefits package
available to all Cellomics full-time employees, including full coverage of
health care (medical and dental), three weeks paid-time-off per year, paid
holidays, and participation in the 401k retirement plan.

In connection with your employment, you will be granted an option to purchase
15,000 shares of Common Stock of the Company at an exercise price of $0.56 per
share. Twenty-five percent (25%) of the shares subject to such option will vest
on the anniversary date of the grant on an annual basis over four years from the
date of grant.

The Company will offer you $10,000.00 for use in any way that you deem
appropriate for your transition to Cellomics, Inc.

This offer is subject to submission of an I-9 form and satisfactory
documentation with respect to your identification and right to work in the
United States no later than three days after your employment begins.

As a Cellomics employee, you will be expected to abide by company rules and
regulations. You will specifically be required to sign an acknowledgment that
you have read and understand the company rules of conduct, which will be
included in a handbook which the company will soon complete and distribute. You
will be expected to sign and comply with a proprietary information and
nondisclosure agreement which requires, among other provisions, the assignment
of patent rights to any invention made during your employment at Cellomics, Inc.
and nondisclosure of proprietary information.

As an employee, you may terminate your employment at any time and for any reason
whatsoever with notice to Cellomics, Inc. We request that, in the event of
resignation, you give the company at least one month notice. Similarly,
Cellomics, Inc. may terminate your employment at anytime and for any reason
whatsoever, with or without cause. Furthermore, this mutual termination of
employment arrangement supersedes all our prior written and oral communication
with you and can only be modified by written agreement signed by you and
Cellomics, Inc. In the event your employment with the Company is terminated for
any reason other than for cause in the first two years of employment, you will
receive salary continuation and benefits for a period of time ending on the
earlier of six months from termination or until you begin other full time
employment. This severance payment will be contingent on your agreement to not
be employed by a competing company within one year of your termination date.

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If you wish to accept employment with Cellomics, Inc. under the terms set out
above, please sign and date both copies of this letter, and return one to me by
October 15, 1998. If you accept our offer, we would like you to start on or
before November 15, 1998

I am personally enthusiastic about you joining Cellomics and helping to build an
exciting company. I look forward to a favorable reply.

Sincerely,

D. Lansing Taylor, Ph.D.
President & CEO

Enclosure(s)

Accepted:

/s/ Alan W. Seadler, Ph.D.
--------------------------
Alan W. Seadler, Ph.D.

10-14-98
--------------------------
Dated

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