Document:

Exhibit 10.5

 

Nondisclosure,
Noncompetition and

Invention Assignment Agreement

 

This
Nondisclosure, Noncompetition and Invention Assignment Agreement (this “Agreement”) is made by and between
Senesco Technologies, Inc., a Delaware corporation, and its wholly-owned subsidiaries, Senesco, Inc., a New Jersey
corporation and Fabrus, Inc., a Delaware corporation (hereinafter collectively, the “Employer”) and [___]
(“Employee”), to be effective as of [    ], 2014:

 

1.            Confidential
Information and Company Property.

 

1.1        Employee
acknowledges that Employer and its subsidiaries and their respective successors (hereinafter collectively, the
“Company”) possess certain Confidential Information that has been and may be revealed to or learned by Employee
during Employee’s employment with the Company. Employee acknowledges that the term “Confidential
Information” includes all information that has or could have commercial value or other utility in the Company’s
Business, or the unauthorized disclosure of which could be detrimental to the Company’s interests, whether or not such
information is specifically identified as Confidential Information by the Company.

 

1.2        Employee
acknowledges that the Company’s Business includes all businesses in which the Company is planning or preparing to
engage and all businesses in which the Company is currently engaged as well as such other businesses as the Company may
enter, plan to enter, or prepare to enter subsequent to the date that this Agreement is executed.

 

1.3        By
way of example and not limitation, Confidential Information includes any and all information, whether or not meeting the
legal definition of a trade secret, concerning the Company’s actual, planned or contemplated (i) marketing plans,
business plans, strategies, forecasts, budgets, projections and costs; (ii) personnel information; (iii) customer, vendor and
supplier lists; (iv) customer, vendor and supplier needs, transaction histories, contacts, volumes, characteristics,
agreements and prices; (v) promotions, operations, sales, marketing, and research and development; (vi) business operations,
internal structures and financial affairs; (vii) software and operating systems and procedures; (viii) pricing structure of
the Company’s services and products; (ix) proposed services and products; (x) contracts with other parties; (xi)
performance characteristics of the Company’s products; and (xii) Inventions and Works as defined in Section 4.
Confidential Information does not include information that has become widely known to the public other than through the
improper disclosure of Employee. Notwithstanding anything to the contrary in this Agreement, however, Confidential
Information includes any and all information that the Company is obligated to maintain as confidential.

 

1.4        During
the term of Employee’s employment with the Company and thereafter, Employee will not, directly or indirectly, use or disclose
to anyone, or authorize disclosure or use by anyone of, any of the Confidential Information revealed to, learned by or created
by Employee during the course of Employee’s employment with the Company, unless such use or disclosure is both consistent
with the Company’s obligations and is for the sole purpose of carrying out Employee’s duties to the Company. Employee
further agrees that Employee’s will take all reasonable efforts to protect the confidentiality of Confidential Information.

 

     

     

    

  

1.5        Employee
acknowledges that Confidential Information is essential to the Company’s Business. Employee will not remove from the
Company’s place of business any document or other medium containing Confidential Information, or other Company
property, without the permission of the Company, which permission the Company may in its absolute discretion withhold.
Employee agrees that Employee will not make any copies of Confidential Information or other Company property except as
authorized by the Company. Employee agrees that at the cessation of Employee’s employment Employee will return to the
Company immediately any and all Company property and documents and other media containing Confidential Information (and all
copies thereof) in Employee’s possession, custody or control. The Company’s property includes, but is not limited
to, all financial books, records, instruments and documents; customer lists; data; reports; programs; software; hardware;
tapes; rolodexes; telephone and address books; card decks; listings; programming; customer files and records; and any and all
other instruments, records and documents recorded or stored on any medium whatsoever relating or pertaining, directly or
indirectly, to corporations, governmental entities and other persons and entities with whom the Company has or has had
contractual relations, the services or products provided by the Company, or the Company’s Business or business
affairs.

 

1.6        If
Employee is requested or required (by oral questions, interrogatories, requests for information or documents, subpoena, civil
investigative demand or other process) to disclose Confidential Information, Employee will immediately notify the Company of
such request or requirement so that the Company may take any action deemed by the Company to be necessary or advisable to
protect the confidentiality of the Confidential Information. Unless the Company waives the protections of this Agreement in
writing, Employee agrees to take all lawful steps to protect the confidentiality of the Confidential Information and to
cooperate fully with the Company’s efforts to protect the confidentiality of the Confidential Information, including,
but not limited to, seeking a protective order and refusing to produce such Confidential Information unless compelled to do
so by a final order that has been upheld by the highest appellate court having jurisdiction over the matter. If Employee is
ultimately compelled to disclose Confidential Information, Employee agrees to take all lawful efforts to limit the
dissemination of, and maintain the confidentiality of, the Confidential Information. Employer agrees to reimburse Employee
for reasonable expenses incurred by Employee in complying with this Section 1.6.

 

2.            Employee
Responsibilities and Restrictive Covenants.

 

2.1        Employee
agrees to devote Employee’s best efforts and entire work time and attention to the
Company’s Business during the term of Employee’s employment with the Company. While the Company does not seek to
interfere with the off-duty and personal conduct of its employees, certain conduct may interfere with the Company’s
legitimate business interests. Employee agrees that, during the term of Employee’s employment, except as otherwise
approved in writing by the Company, which approval the Company may in its absolute discretion withhold, Employee will not
engage in any outside business activity that conflicts with, or adversely affects, Employee’s job performance. Employee
must disclose to the Board of Directors his involvement in any outside business activity that may conflict with or be adverse
to the interests of the Company. Employee further agrees that, during the term of Employee’s employment, except as
otherwise approved in writing by the Company, which approval the Company may in its absolute discretion withhold, Employee
will not engage in:

 

     

     

    

  

(a)        Employment
that conflicts with Employee’s work schedule, duties, or responsibilities;

 

(b)        Employment
that is incompatible with Employee’s employment with the Company;

 

(c)        Employment
that impairs or has a detrimental effect on Employee’s work performance with the Company;

 

(d)        Employment
that requires Employee to conduct work or related activities on the Company’s property during Employee’s working hours
or to use the Company’s facilities and/or equipment.

 

2.2        Employee
further agrees that Employee will not take any action inconsistent with the fiduciary relationship of an employee to his corporate
employer. This shall not prohibit Employee from owning stock or other securities of a competitor of the Company or any subsidiary
or affiliate of such competitor so long as Employee’s ownership does not interfere with Employee’s job performance.

 

2.3        Employee
agrees that, for a period of twelve (12) months after the cessation of Employee’s employment, Employee will not, either directly
or indirectly, or for himself/herself or through, on behalf of, or in conjunction with any person, persons or legal entity, own,
maintain, operate, engage in, assist, be employed by, or have any interest in any business engaging in or planning to be engaged
in the Company’s business in which Employee works.

 

2.4        Employee
agrees that, during the term of Employee’s employment with the Company, and for a period of twelve (12) months thereafter,
Employee will not, either directly or indirectly, or for himself/herself or through, on behalf of or in conjunction with any person,
persons or legal entity, persuade, induce or attempt to persuade or induce any employee or person who has provided services to
the Company as an employee or independent contractor or employee of an independent contractor to leave his/her employment with
the Company or to refrain from providing services to the Company.

 

2.5        Employee
agrees that, for a period of twelve (12) months after the cessation of Employee’s employment, Employee will promptly inform
Employer in writing of any employment or other business affiliations that Employee has with any business or business entity offering
or planning to offer a service or product in competition with the Company. Such information will include, but not be limited to
(i) the name and address of the business or business entity with which Employee has such a relationship; and (ii) the general nature
of Employee’s business-related activities. To the extent requested by Employer, Employee agrees to provide such additional
information as Employer reasonably believes to be necessary for Employer to ascertain whether Employee is complying with this Agreement.

 

     

     

    

 

2.6        Employer
and Employee agree that Sections 2.1 through 2.3 hereof are not intended to, and do not, prevent ownership of up to 5% or $100,000,
whichever is less, of any class of equity or debt securities that are traded on a national securities exchange.

 

3.            Company
Access.

 

3.1        Employee
agrees and consents that, during the term of Employee’s employment with the Company and thereafter, the Company may
review, audit, intercept, access and disclose all messages created, stored, received or sent over the electronic mail and
Internet access systems provided by the Company, with or without notice to Employee, and that such review, audit,
interception, access or disclosure may occur during or after working hours. Employee further consents and agrees that the
Company may, at any time, access, review and disclose the contents of all computers, computer disks and other data-storage
equipment and devices, files, desks, drawers, closets, cabinets and work stations that are either on the Company’s
premises or owned or provided by the Company.

 

4.            Intellectual
Property.

 

4.1        Employee
agrees to disclose fully, promptly and in writing to Employer any and all Inventions and Works, separately defined below,
that are conceived, made, reduced to practice, developed, authored, created, drawn or written at any time while Employee is
employed by the Company and for a period of six (6) months thereafter. Employee will generate and provide to the Company
adequate and current written records of all Inventions and Works in the form of notes, sketches, drawings, reports, notebooks
or other documents relating thereto or in such other form as will be requested by the Company, which records and any copies
thereof will be and will remain the exclusive property of Employer and will be available to the Company at all times.

 

(a)  Employer
and Employee agree that the term “Inventions” is defined in this Agreement to include any and all new or useful ideas,
developments, discoveries, improvements, designs, formulas, modifications, trademarks, service marks, trade secrets, and other
intellectual property, whether patentable or not (including without limitation any technology, computer programs, software, test,
concept, idea, apparatus, device, mechanism, equipment, machinery, process, method, composition of matter, formula or technique),
and all know-how related thereto, that Employee conceives, makes, reduces to practice, or develops, solely or jointly with others,
that (i) relate to the actual or contemplated business, work or activities of the Company, (ii) result from or are suggested by
any work that Employee has done or may do on behalf of the Company, or by any information that Employee may receive while employed
by the Company, or (iii) are developed, tested, improved or investigated either in part or entirely on time for which Employee
was paid by the Company, or with the use of premises, equipment or property provided, owned, leased or contracted for by or on
behalf of the Company.

 

     

     

    

  

4.2        Employer
and Employee agree that the term “Works” is defined in this Agreement to include any and all materials for which copyright
protection may be obtained, including without limitation literary works (including books, pamphlets, articles and other writings),
mask works, artistic works (including designs, graphs, drawings, blueprints and other graphic works), computer programs, compilations,
recordings, photographs, motion pictures and other audio-visual works that Employee authors, conceives, creates, draws, makes or
writes, solely or jointly with others, that (i) relate to the actual or contemplated business, work or activities of the Company,
(ii) result from or are suggested by any work that Employee has done or may do on behalf of the Company, or by any information
that Employee may receive while employed by the Company, or (iii) are developed, tested, improved or investigated either in part
or entirely on time for which Employee was paid by the Company, or with the use of premises, equipment or property provided, owned,
leased or contracted for by or on behalf of the Company.

 

4.3        Employee
agrees to assign, transfer and convey, and hereby assigns, transfers and conveys, to Employer all of the right, title and interest
in and to any and all such Inventions and Works that Employee has or may acquire in such Inventions or Works that are conceived,
made, reduced to practice, developed, authored, created, drawn or written at any time while Employee is employed by the Company.
Employee further agrees that for a period of six (6) months after the end of the employment relationship, Employee shall notify
and inform Employer of any and all Inventions and Works Employee conceives, makes, or reduces to practice, develops, authors, or
creates, and agrees to assign, transfer and convey, and hereby assigns, transfers and conveys, to the Company all of the right,
title and interest in and to any and all such Inventions and Works that Employee conceives, makes, reduces to practice, develops,
authors, or creates, drawn or written, arising from, based upon, relating to, utilizing, or employing Company’s proprietary,
confidential, or trade secret information or the use of the Company’s facilities. Employee agrees that Employer will be the
sole owner of all patents, copyrights, trademarks and other intellectual property rights in connection therewith, and agrees to
take all such actions as may be requested by the Company during Employee’s employment with the Company and at any time thereafter,
with respect to any such Inventions or Works to confirm or evidence such assignment, transfer, conveyance or ownership, and to
assist in the Company’s maintenance, enforcement, licensing, assignment, transfer, or conveyance of rights in respect of
the Inventions or Works.

 

4.4        By
way of example and not limitation, at any time and from time to time, upon the request of the Company, Employee agrees to execute,
acknowledge, swear to, seal and deliver to the Company any and all lawful instruments, documents and papers, give evidence and
do any and all other lawful acts that, in the opinion of the Company, are or may be necessary or desirable to document such assignment,
transfer and conveyance or to enable the Company to file and prosecute applications for, and to acquire, maintain and enforce any
and all patents, trademarks, copyrights and other property rights under United States, local, state or foreign law with respect
to, any such Inventions or Works, or to obtain any extension, validation, reissue, continuance or renewal of any such patent, trademark,
copyright or other intellectual property right. By way of further example and not limitation, Employee agrees to meet with Company
representatives or attorneys for the purpose of initiating, maintaining or defending litigation, administrative or other proceedings,
and to participate fully in litigation, administrative or other proceedings as requested by the Company. In the event that the
Company may be unable, for any reason whatsoever, after reasonable effort, to secure Employee’s signature on any patent,
copyright, trademark or other intellectual property application or other papers, Employee hereby irrevocably designates and appoints
the Company and its duly authorized officers and agents as Employee’s agent and attorney-in-fact to act for and on behalf
of Employee to execute, acknowledge, swear to, seal and deliver to the Company and file any such application or applications or
other papers, and to do all other lawfully permitted acts to further the provisions of this Section 4.

 

     

     

    

 

4.5        Employer
agrees to reimburse Employee for reasonable expenses incurred by Employee in complying with the provisions of Sections 4.3 and
4.4 of this Agreement. Employer and Employee agree that Employee is not entitled to additional compensation beyond that paid to
Employee for the period of time that Employee is employed by the Company, which compensation, along with Employer’s understandings
set forth in this Agreement, is expressly acknowledged to be adequate consideration for all of Employee’s promises and obligations
set forth in this Agreement.

 

4.6        Employee
expressly acknowledges and states that all Works that are made by Employee (solely or jointly with others) are being created at
the instance of Employer and are “works made for hire,” as that term is defined in the Copyright Act of 1976, 17 U.S.C.
§ 101. In the event that such laws are inapplicable or in the event that any such Works, or any part thereof, are determined
by a court of competent jurisdiction not to be a work made for hire, this Agreement will operate as an irrevocable and unconditional
assignment by Employee to Employer of all Employee’s right, title and interest (including, without limitation, all rights
in and to the copyrights throughout the world, including the right to prepare derivative works and the rights to all renewals and
extensions) in the Works in perpetuity.

 

4.7        Employee
represents that Exhibit A to this Agreement describes all Inventions and Works, whether patentable or not, that have been
conceived, made, reduced to practice, developed, authored, created, drawn or written prior to Employee’s employment by the
Company; provided, however, that Employee has not disclosed in Exhibit A information that is a trade secret belonging to
another, or that is the subject of a contract preventing Employee’s disclosure of such information to the Company.

 

5.            Employee
Representations.

 

5.1        Employee
represents and warrants that this Agreement and Employee’s employment by the Company do not conflict with and will not be
constrained by any prior business relationship or contract, and that Employee does not possess trade secrets or other proprietary
information arising out of any prior business relationship or contract that, in Employee’s best judgment, would be utilized
in connection with Employee’s employment with the Company. Employee further agrees that Employee will not disclose any such
trade secrets or other proprietary information to the Company or others.

 

5.2        Employee
represents and warrants that if Employee’s employment with the Company were to terminate, Employee could earn a living while
fully complying with all of the terms of this Agreement and that the restrictions contained in this Agreement are reasonable and
necessary to protect the Company’s legitimate interests in its Confidential Information and customer relationships.

 

     

     

    

 

6.            Interpretation.

 

6.1        Wherever
this Agreement contemplates that Employee will have an obligation or restriction at or after the term of Employee’s employment
with the Company, Employee agrees that that obligation or restriction will exist without regard to which party to the Agreement
terminates the employment relationship, and without regard to the reason (or lack thereof) for the termination of the employment
relationship.

 

6.2        Employer
and Employee agree that this Agreement constitutes the entire understanding and agreement of Employee and the Company with respect
to the subject matter of this Agreement, and supersedes all prior and contemporaneous agreements or understandings, inducements
or conditions, express or implied, written or oral, between the Company and Employee.

 

6.3        Employer
and Employee agree that if any provision of this Agreement, or the application thereof, will for any reason and to any extent be
invalid or unenforceable, such provision will be deemed severable and the remainder of this Agreement will remain valid and fully
enforceable.

 

6.4        Employer
and Employee agree that if all or any portion of a covenant is held unreasonable or unenforceable by a court or agency having valid
jurisdiction in a final decision, Employee will be bound by any lesser covenant subsumed within the terms of such covenant, which
lesser covenant imposes the maximum duty permitted by law, as if the resulting covenant were separately stated in and made a part
of this Agreement.

 

6.5        Employer
and Employee agree that the headings in this Agreement are included solely for convenience and will be given no effect in the construction
of this Agreement.

 

6.6        Employer
and Employee agree that, although this Agreement was drafted by Employer, it accurately reflects both parties’ intent and
understanding and should not be presumptively construed against the Company in the event that there is any dispute over the meaning
or intent of any provision.

 

7.            Enforcement.

 

7.1        If
requested by Employer, Employee agrees, at any time during the term of Employee’s employment and thereafter, to reaffirm
in writing the obligations imposed by, and Employee’s past compliance with, any or all of the provisions of this Agreement.

 

7.2        Employee
agrees that if Employee engages in any activities prohibited by this Agreement or fails to take actions required by this Agreement,
irreparable harm to the Company will likely result, for which a remedy in the form of damages may not be adequate or otherwise
ascertainable. Consequently, Employer will be entitled to temporary, preliminary and permanent injunctive relief against Employee.
This section will not limit any other legal or equitable remedies that Employer may have against Employee for violations of these
restrictions.

 

7.3        Employer
and Employee agree that this Agreement will be governed by the laws of the State of New Jersey, without giving effect to the conflict
of laws provisions thereof. All suits, proceedings and other actions relating to, arising out of or in connection with this Agreement
will be submitted solely to the in personam jurisdiction in the State of New Jersey . Employee hereby waives any claims against
or objections to such in personam jurisdiction.

 

     

     

    

  

7.4        Employer
and Employee agree that, in any lawsuit for breach of this Agreement, the prevailing party will be entitled to recover its or his/her
reasonable attorneys’ fees and costs, including expert witness fees, unless there is an express determination by the court
that the nonprevailing party’s position was substantially justified.

 

8.            General.

 

8.1        Employer
and Employee agree that this Agreement will be binding upon and inure to the benefit of the Company and its successors and assigns.
This Agreement may be assigned in whole or in part by Employer to a successor to all or substantially all of the business or assets
of Employer or the subportion of the business or assets of Employer that relate to Employee’s duties; or to any division
or part of Employer; or to any subsidiary, affiliate or division; or to any entity that is majority-owned by Employer or its subsidiaries,
divisions or affiliates.

 

8.2        Employer
and Employee agree that any term or provision of this Agreement may be amended or waived only by a writing signed by Employee and
an officer of Employer. The failure of either party to enforce any of the provisions in this Agreement will not be construed to
be a waiver of the right of that party to enforce such provision thereafter.

 

8.3        Employee
agrees that this Agreement is not confidential, and that the Company may, during the term of Employee’s employment with the
Company and thereafter, provide copies of this Agreement to others, including persons or entities that may employ, do business
with or consider employing or doing business with Employee in the future.

 

8.4        Employee
and Employer agree that this Agreement may be executed in one or more counterparts, each of which shall be deemed an original,
but all of which together shall constitute one and the same instrument. This Agreement shall become effective upon the execution
of a counterpart hereof by each of the parties hereto.

 

8.5        By
Employee’s signature below, Employee acknowledges that Employee (i) has had sufficient opportunity to read each provision
of this Agreement and understands each provision, (ii) has had an opportunity to review the Agreement with legal counsel of Employee’s
choice, (iii) is not under duress and (iv) is not relying on any representations or promises that are not set forth in the Agreement.

 

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]

 

     

     

    

 

	EMPLOYEE:	 	 	EMPLOYER:	 
	 	 	 	 	 
	Signature: 	 	 	Signature:	 
	 	 	 	 	 
	Name (Print): 	 	 	Name (Print):	 
	 	 	 	 	 
	Title: 	 	 	Title:	 
	 	 	 	 	 
	Date: 	 	 	Date:	 

 

Exhibit A attached: Yes_______ No______

 

     

     

    

 

Exhibit A

 

The following is a complete list of all
Inventions and Works that have been conceived, made, reduced to practice, developed, authored, created, drawn or written by
me alone or jointly with others prior to my engagement by the Company.

	 	 	 
	 	 	 
	 	 	 
	 	 	 
	 	 	 
	 	 	 
	 	 	 

 

Due to a preexisting contract
with another party, I cannot disclose certain Inventions or Works that would otherwise be included on the above list.

_________additional
sheets are attached.

 

(number)

 

EMPLOYEE:

 

	 	Signature:	 	 
	 	 	 	 
	 	Name (Print):	 	 
	 	 	 	 
	 	Title:	 	 
	 	 	 	 
	 	Date:Exhibit 10.20

 

REGISTRATION RIGHTS AGREEMENT

 

THIS
REGISTRATION RIGHTS AGREEMENT (this “Agreement”) is made as of
                   2015, among the undersigned
corporation (the “Company”), and each signatory hereto (each, an “Investor” and
collectively, the “Investors”). Capitalized terms not otherwise defined herein shall have the
meaning ascribed to them in the Subscription Agreement (as defined below).

 

RECITALS

 

WHEREAS, the Company
each Investor are parties to a Subscription Agreement (collectively, the “Subscription Agreements”), dated as
of the date hereof, as such may be amended and supplemented from time to time;

 

WHEREAS, the Investors’
obligations under the Subscription Agreements are conditioned upon certain registration rights under the Securities Act of 1933,
as amended (the “Securities Act”); and

 

WHEREAS, the Investors
and the Company desire to provide for the rights of registration under the Securities Act as are provided herein upon the execution
and delivery of this Agreement by such Investors and the Company.

 

NOW, THEREFORE, in
consideration of the promises, covenants and conditions set forth herein, the parties hereto hereby agree as follows:

 

1. Registration Rights.

 

1.1           Definitions. As
used in this Agreement, the following terms shall have the

meanings set forth below:

 

(a)          “Commission”
means the United States Securities and Exchange Commission.

 

(b)          “Common
Stock” means the Company’s common stock, par value $0.01 per share.

 

(c)          “Effectiveness
Date” means the date that is one hundred and twenty (120) days after the Filing Date.

 

(d)          “Exchange
Act” means the Securities Exchange Act of 1934, as amended.

 

(e)          “Filing
Date” means the date that is forty-five (45) days after the Trigger Date.

 

(f)          “Investor”
means any person owning Registrable Securities who becomes party to this Agreement by executing a counterpart signature page hereto,
or other agreement in writing to be bound by the terms hereof, which is accepted by the Company.

 

    	 

     

    

 

(g)          The
terms “register,” “registered” and “registration” refer to a registration effected
by preparing and filing a registration statement or similar document in compliance with the Securities Act, and the declaration
or ordering of effectiveness of such registration statement or document.

 

(h)          “Registrable
Securities” 200% of the maximum number of Warrant Shares issuable upon exercise of the Warrants underlying the Units
issued pursuant to the Subscription Agreement as of the day immediately preceding the applicable date of determination (without
taking into account any limitations on the exercise of the Warrants); provided, however, that Registrable Securities shall
not include any securities of the Company that have previously been registered and remain subject to a currently effective registration
statement or which have been sold to the public either pursuant to a registration statement or Rule 144, or which have been sold
in a private transaction in which the transferor’s rights under this Section 1 are not assigned, or which may be sold immediately
without registration under the Securities Act and without restriction or imitation pursuant to Rule 144 and without the requirement
to be in compliance with Rule 144(c)(1).

 

(i)          “Rule
144” means Rule 144 as promulgated by the Commission under the Securities Act, as such Rule may be amended from time
to time, or any similar successor rule that may be promulgated by the Commission.

 

(j)          “Rule
415” means Rule 415 as promulgated by the Commission under the Securities Act, as such Rule may be amended from time
to time, or any similar successor rule that may be promulgated by the Commission.

 

(k)          “Trigger
Date” means the Final Closing Date.

 

1.2            Company
Registration.

 

(a)          On
or prior to the Filing Date, the Company shall prepare and file with the Commission a registration statement covering the Registrable
Securities for an offering to be made on a continuous basis pursuant to Rule 415. The registration statement shall be on Form S-1
or, if the Company is so eligible, on Form S-3 (except if the Company is not then eligible to register for resale the Registrable
Securitvies on Form S-1 or Form S-3, as the case may be, in which case such registration shall be on another appropriate form in
accordance herewith) and shall contain (unless otherwise directed by Investors holding an aggregate of at least 60% of the Registrable
Securities on an “as converted” and “as exercised” basis including the approval of the Lead Investor) substantially
the “Plan of Distribution” attached hereto as Annex A. The Company shall cause the registration statement
to become effective and remain effective as provided herein. The Company shall use its reasonable best efforts to cause the registration
statement to be declared effective under the Securities Act as soon as possible and, in any event, by the Effectiveness Date. The
Company shall use its reasonable best efforts to keep the registration statement continuously effective under the Securities Act
until all Registrable Securities covered by such registration statement have been sold, or may be sold without the requirement
to be in compliance with Rule 144(c)(1) and otherwise without restriction or limitation pursuant to Rule 144, as determined by
the counsel to the Company (the “Effectiveness Period”).

 

    	 

     

    

 

(b)          The
Company shall pay to Investors a fee of 1% per month of the Investors’ investment, payable in cash, for every thirty (30)
day period up to a maximum of 6%, (i) following the Filing Date that the registration statement has not been filed and (ii) following
the Effectiveness Date that the registration statement has not been declared effective; provided, however, that the Company
shall not be obligated to pay any such liquidated damages if (i) the Registrable Securities that would other be covered by the
registration statement may be sold without the requirement to be in compliance with Rule 144(c)(1) and otherwise without restriction
or limitation pursuant to Rule 144 under the Securities Act or (ii) the Company is unable to fulfill its registration obligations
as a result of rules, regulations, positions or releases issued or actions taken by the Commission pursuant to its authority with
respect to “Rule 415”, and the Company registers at such time the maximum number of shares of Common Stock permissible
upon consultation with the staff of the Commission.

 

(c)          If
during the Effectiveness Period, the number of Registrable Securities at any time exceeds 100% of the number of shares of Common
Stock then registered in a registration statement, the Company shall file as soon as reasonably practicable after receiving written
notice from holders of a majority of the Registrable Securities not registered an additional registration statement covering the
resale of not less than the number of such Registrable Securities.

 

(d)          The
Company shall bear and pay all expenses reasonably incurred in connection with any registration, filing or qualification of Registrable
Securities with respect to the registrations pursuant to this Section 1.2 for each Investor, including (without limitation) all
registration, filing and qualification fees, printer’s fees, accounting fees and fees and disbursements of counsel for the
Company, but excluding any brokerage or underwriting fees, discounts and commissions relating to Registrable Securities and fees
and disbursements of counsel for the Investors.

 

(e)          If
at any time during the Effectiveness Period there is not an effective Registration Statement covering all of the Registrable Securities,
then the Company shall notify each Investor in writing at least fifteen (15) days prior to the filing of any registration statement
under the Securities Act, in connection with a public offering of shares of Common Stock (including, but not limited to, registration
statements relating to secondary offerings of securities of the Company but excluding any registration statements (i) on Form
S-4 or S-8 (or any successor or substantially similar form), or of any employee stock option, stock purchase or compensation plan
or of securities issued or issuable pursuant to any such plan, or a dividend reinvestment plan, (ii) otherwise relating to any
employee, benefit plan or corporate reorganization or other transactions covered by Rule 145 promulgated under the Securities
Act, (iii) on any registration form which does not permit secondary sales or does not include substantially the same information
as would be required to be included in a registration statement covering the resale of the Registrable Securities. In the event
an Investor desires to include in any such registration statement all or any part of the Registrable Securities held by such Investor,
the Investor shall within ten (10) days after the above-described notice from the Company, so notify the Company in writing, including
the number of such Registrable Securities such Investor wishes to include in such registration statement. If an Investor decides
not to include all of its Registrable Securities in any registration statement thereafter filed by the Company such Investor shall
nevertheless continue to have the right to include any Registrable Securities in any subsequent registration statement or registration
statements as may be filed by the Company with respect to the offering of the securities, all upon the terms and conditions set
forth herein.

 

    	 

     

    

  

1.3 Obligations
of the Company. Whenever required under this Section 1 to effect the registration of any Registrable Securities, the
Company shall, as expeditiously as reasonably possible:

 

(a)          Prepare
and file with the Commission a registration statement with respect to such Registrable Securities and use its reasonable best efforts
to cause such registration statement to become effective and to keep such registration statement effective during the Effectiveness
Period;

 

(b)          Prepare
and file with the Commission such amendments and supplements to such registration statement and the prospectus used in connection
with such registration statement as may be necessary to comply with the provisions of the Securities Act with respect to the disposition
of all securities covered by such registration statement;

 

(c)          Furnish
to the Investors such numbers of copies of a prospectus, including a preliminary prospectus, in conformity with the requirements
of the Securities Act, and such other documents as they may reasonably request in order to facilitate the disposition of Registrable
Securities owned by them (provided that the Company would not be required to print such prospectuses if readily available to Investors
from any electronic service, such as on the EDGAR filing database maintained at www.sec.gov);

 

(d)          Use
its reasonable best efforts to register and qualify the securities covered by such registration statement under such other securities’
or blue sky laws of such jurisdictions as shall be reasonably requested by the Investors; provided that the Company shall not be
required in connection therewith or as a condition thereto to qualify to do business or to file a general consent to service of
process in any such states or jurisdictions;

 

(e)          In
the event of any underwritten public offering, enter into and perform its obligations under an underwriting agreement, in usual
and customary form, with the managing underwriter(s) of such offering (each Investor participating in such underwriting shall also
enter into and perform its obligations under such an agreement);

 

(f)          Promptly
notify each Investor holding Registrable Securities covered by such registration statement at any time when a prospectus relating
thereto is required to be delivered under the Securities Act, within one business day, (i) of the effectiveness of such registration
statement, or (ii) of the happening of any event as a result of which the prospectus included in such registration statement, as
then in effect, includes an untrue statement of a material fact or omits to state a material fact required to be stated therein
or necessary to make the statements therein not misleading in the light of the circumstances then existing;

 

(g)          Cause
all such Registrable Securities registered pursuant hereto to be listed on each securities exchange or nationally recognized quotation
system on which similar securities issued by the Company are then listed; and

 

    	 

     

    

 

(h)          Provide
a transfer agent and registrar for all Registrable Securities registered pursuant hereunder and a CUSIP number for all such Registrable
Securities, in each case not later than the effective date of such registration.

 

1.4 Furnish
Information. It shall be a condition precedent to the Company’s obligations to take any action pursuant to this Section
1 with respect to the Registrable Securities of any selling Investor that such Investor shall furnish to the Company such information
regarding such Investor, the Registrable Securities held by such Investor, and the intended method of disposition of such securities
in the form attached to this Agreement as Annex B, or as otherwise reasonably required by the Company or the managing underwriters,
if any, to effect the registration of such Investor’s Registrable Securities.

 

1.5 Delay
of Registration. No Investor shall have any right to obtain or seek an injunction restraining or otherwise delaying any such
registration as the result of any controversy that might arise with respect to the interpretation or implementation of this Section
1.

 

1.6 Indemnification.

 

(a)          To
the extent permitted by law, the Company will indemnify and hold harmless each Investor, any underwriter (as defined in the Securities
Act) for such Investor and each person, if any, who controls such Investor or underwriter within the meaning of the Securities
Act or the Exchange Act, against any losses, claims, damages or liabilities (joint or several) to which any of the foregoing persons
may become subject under the Securities Act, the Exchange Act or other federal or state securities law, insofar as such losses,
claims, damages or liabilities (or actions in respect thereof) arise out of or are based upon any of the following statements,
omissions or violations (collectively, a “Violation”): (i) any untrue statement or alleged untrue statement
of a material fact contained in a registration statement, including any preliminary prospectus or final prospectus contained therein
or any amendments or supplements thereto (collectively, the “Filings”), (ii) the omission or alleged omission
to state in the Filings a material fact required to be stated therein, or necessary to make the statements therein not misleading,
or (iii) any violation or alleged violation by the Company of the Securities Act, the Exchange Act, any state securities law or
any rule or regulation promulgated under the Securities Act, the Exchange Act or any state securities law; and the Company will
pay any legal or other expenses reasonably incurred by any person to be indemnified pursuant to this Section 1.6(a) in connection
with investigating or defending any such loss, claim, damage, liability or action; provided, however, that the indemnity
agreement contained in this Section 1.6(a) shall not apply to amounts paid in settlement of any such loss, claim, damage, liability
or action if such settlement is effected without the consent of the Company (which consent shall not be unreasonably withheld),
nor shall the Company be liable in any such case for any such loss, claim, damage, liability or action to the extent that it arises
out of or is based upon a Violation that occurs in reliance upon and in conformity with written information furnished expressly
for use in connection with such registration by any such Investor, underwriter or controlling person.

 

    	 

     

    

  

(b)          To
the extent permitted by law, each Investor will indemnify and hold harmless the Company, each of its directors, each of its officers
who has signed the registration statement, each person, if any, who controls the Company within the meaning of the Securities Act
or the Exchange Act, any underwriter, any other Investor selling securities in such registration statement and any controlling
person of any such underwriter or other Investor, against any losses, claims, damages or liabilities (joint or several) to which
any of the foregoing persons may become subject under the Securities Act, the Exchange Act or other federal or state securities
law, insofar as such losses, claims, damages or liabilities (or actions in respect thereto) arise out of or are based upon any
Violation, in each case to the extent (and only to the extent) that such Violation occurs in reliance upon and in conformity with
written information furnished by such Investor expressly for use in connection with such registration; and each such Investor will
pay any legal or other expenses reasonably incurred by any person to be indemnified pursuant to this Section 1.6(b) in connection
with investigating or defending any such loss, claim, damage, liability or action; provided, however, that the indemnity
agreement contained in this Section 1.6(b) shall not apply to amounts paid in settlement of any such loss, claim, damage, liability
or action if such settlement is effected without the consent of the Investor (which consent shall not be unreasonably withheld);
provided, however, in no event shall any indemnity under this subsection 1.6(b) exceed the net proceeds received by such
Investor upon the sale of the Registrable Securities giving rise to such indemnification obligation.

 

(c)          Promptly
after receipt by an indemnified party under this Section 1.6 of notice of the commencement of any action (including any governmental
action), such indemnified party will, if a claim in respect thereof is to be made against any indemnifying party under this Section
1.6, deliver to the indemnifying party a written notice of the commencement thereof and the indemnifying party shall have the right
to participate in, and, to the extent the indemnifying party so desires, jointly with any other indemnifying party similarly noticed,
to assume the defense thereof with counsel mutually satisfactory to the parties; provided, however, that an indemnified
party (together with all other indemnified parties that may be represented without conflict by one counsel) shall have the right
to retain one separate counsel, with the fees and expenses to be paid by the indemnifying party, if representation of such indemnified
party by the counsel retained by the indemnifying party would be inappropriate due to actual or potential differing interests between
such indemnified party and any other party represented by such counsel in such proceeding. The failure to deliver written notice
to the indemnifying party within a reasonable time of the commencement of any such action, if materially prejudicial to its ability
to defend such action, shall relieve such indemnifying party of any liability to the indemnified party under this Section 1.6,
but the omission so to deliver written notice to the indemnifying party will not relieve it of any liability that it may have to
any indemnified party otherwise than under this Section 1.6.

 

(d)          If
the indemnification provided for in Sections 1.6(a) and (b) is held by a court of competent jurisdiction to be unavailable to an
indemnified party with respect to any loss, claim, damage or expense referred to herein, then the indemnifying party, in lieu of
indemnifying such indemnified party hereunder, shall contribute to the amount paid or payable by such indemnified party as a result
of such loss, claim, damage or expense in such proportion as is appropriate to reflect the relative fault of the indemnifying party
on the one hand and of the indemnified party on the other in connection with the statements or omissions or alleged statements
or omissions that resulted in such loss, liability, claim or expense as well as any other relevant equitable considerations. The
relative fault of the indemnifying party and of the indemnified party shall be determined by reference to, among other things,
whether the untrue or alleged untrue statement of a material fact relates to information supplied by the indemnifying party or
by the indemnified party and the parties’ relative intent, knowledge, access to information and opportunity to correct or
prevent such statement or omission. In no event shall any Investor be required to contribute an amount in excess of the net proceeds
received by such Investor upon the sale of the Registrable Securities giving rise to such indemnification obligation.

 

    	 

     

    

  

(e)          The
obligations of the Company and Investors under this Section 1.6 shall survive the completion of any offering of Registrable Securities
in a registration statement under this Section 1, and otherwise.

 

1.7 Reports
Under Securities Exchange Act. With a view to making available the benefits of certain rules and regulations of the Commission,
including Rule 144, that may at any time permit an Investor to sell securities of the Company to the public without registration
or pursuant to a registration on Form S-1 or Form S-3, the Company agrees to:

 

(a)          make
and keep public information available, as those terms are understood and defined in Rule 144, at all times after the Final Closing
Date;

 

(b)          take
such action, including the voluntary registration of its Common Stock under Section 12 of the Exchange Act, as is necessary to
enable the Investors to utilize Form S-1 for the sale of their Registrable Securities, such action to be taken as soon as practicable
after the end of the fiscal year in which the registration statement is declared effective;

 

(c)          file
with the Commission in a timely manner all reports and other documents required of the Company under the Securities Act and the
Exchange Act; and

 

(d)          furnish
to any Investor, so long as the Investor owns any Registrable Securities, forthwith upon request (i) a written statement by the
Company that it has complied with the reporting requirements of Rule 144 the Securities Act and the Exchange Act (at any time after
it has become subject to such reporting requirements), or that it qualifies as a registrant whose securities may be resold pursuant
to Form S-1 or Form S-3 (at any time after it so qualifies), (ii) a copy of the most recent annual or quarterly report of the Company
and such other reports and documents so filed by the Company, and (iii) such other information as may be reasonably requested in
availing any Investor of any rule or regulation of the Commission that permits the selling of any such securities without registration
or pursuant to such form.

 

1.8 Transfer
or Assignment of Registration Rights. The rights to cause the Company to register Registrable Securities pursuant to this Section
1 may be transferred or assigned, but only with all related obligations, by an Investor to a transferee or assignee who (a) acquires
at least 25,000 Warrant Shares (on an “as-exercised” basis) (subject to appropriate adjustment for stock splits, stock
dividends and combinations) from such transferring Investor, unless waived in writing by the Company, or (b) holds Registrable
Securities immediately prior to such transfer or assignment; provided, that in the case of (a), (i) prior to such transfer
or assignment, the Company is furnished with written notice stating the name and address of such transferee or assignee and identifying
the securities with respect to which such registration rights are being transferred or assigned, (ii) such transferee or assignee
agrees in writing to be bound by and subject to the terms and conditions of this Agreement and (iii) such transfer or assignment
shall be effective only if immediately following such transfer or assignment the further disposition of such securities by the
transferee or assignee is restricted under the Securities Act.

 

    	 

     

    

 

2. Legend.

 

(a)          Each
certificate representing Warrant Shares held by the Investors shall be endorsed with the following legend:

 

“THE SECURITIES REPRESENTED
BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE
IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”),
AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR
PURSUANT TO AN AVAILABLE EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT
AND IN ACCORDANCE WITH APPLICABLE STATE SECURITIES LAWS AS EVIDENCED BY A LEGAL OPINION OF COUNSEL TO THE TRANSFEROR TO SUCH EFFECT,
THE SUBSTANCE OF WHICH SHALL BE REASONABLY ACCEPTABLE TO THE COMPANY. THE SECURITIES ISSUABLE UPON EXERCISE OF THIS SECURITY MAY
BE PLEDGED IN CONNECTION WITH A BONA FIDE MARGIN ACCOUNT OR OTHER LOAN SECURED BY SUCH SECURITIES.”

 

(b)          The
legend set forth above shall be removed, and the Company shall issue a certificate without such legend to the transferee of the
Warrant Shares represented thereby, if, unless otherwise required by state securities laws, (i) such Warrant Shares have been sold
under an effective registration statement under the Securities Act, (ii) in connection with a sale, assignment or other transfer,
such holder provides the Company with an opinion of counsel, reasonably acceptable to the Company, to the effect that such sale,
assignment or transfer is being made pursuant to an exemption from the registration requirements of the Securities Act, or (iii)
such holder provides the Company with reasonable assurance that the Warrant Shares are being sold, assigned or transferred pursuant
to Rule 144 or Rule 144A under the Securities Act.

 

3. Miscellaneous.

 

3.1
Governing Law. The parties hereby agree that any dispute which may arise between them arising out of or in connection with
this Agreement shall be adjudicated only before a federal court located in the State of New York and they hereby submit to the
exclusive jurisdiction of the federal and state courts of the State of New York with respect to any action or legal proceeding
commenced by any party, and irrevocably waive any objection they now or hereafter may have respecting the venue of any such action
or proceeding brought in such a court or respecting the fact that such court is an inconvenient forum, relating to or arising
out of this Agreement or any acts or omissions relating to the registration of the securities hereunder, and consent to the service
of process in any such action or legal proceeding by means of registered or certified mail, return receipt requested, in care
of the address set forth below or such other address as the undersigned shall furnish in writing to the other.

 

    	 

     

    

  

3.2 WAIVER OF JURY
TRIAL. IN ANY ACTION, SUIT, OR PROCEEDING IN ANY JURISDICTION BROUGHT BY ANY PARTY AGAINST ANY OTHER PARTY, THE PARTIES EACH KNOWINGLY
AND INTENTIONALLY, TO THE GREATEST EXTENT PERMITTED BY APPLICABLE LAW, HEREBY ABSOLUTELY, UNCONDITIONALLY, IRREVOCABLY AND EXPRESSLY
WAIVES FOREVER TRIAL BY JURY

 

3.3 Waivers and
Amendments. This Agreement may be terminated and any term of this Agreement may be amended or waived (either generally or
in a particular instance and either retroactively or prospectively) with the written consent of the Company and Investors holding
at least a 60% of the Registrable Securities then outstanding, including the Lead Investor (the “Majority Investors”).
Notwithstanding the foregoing, additional parties may be added as Investors under this Agreement, and the definition of Registrable
Securities expanded, with the written consent of the Company and the Majority Investors. No such amendment or waiver shall reduce
the aforesaid percentage of the Registrable Securities, the holders of which are required to consent to any termination, amendment
or waiver without the consent of the record holders of all of the Registrable Securities. Any termination, amendment or waiver
effected in accordance with this Section 3.3 shall be binding upon each holder of Registrable Securities then outstanding, each
future holder of all such Registrable Securities and the Company.

 

3.4 Successors
and Assigns. Except as otherwise expressly provided herein, the provisions of this Agreement shall inure to the benefit of,
and be binding upon, the successors, assigns, heirs, executors and administrators of the parties hereto.

 

3.5 Entire Agreement.
This Agreement constitutes the full and entire understanding and agreement among the parties with regard to the subject matter
hereof, and no party shall be liable or bound to any other party in any manner by any warranties, representations or covenants
except as specifically set forth herein.

 

3.6 Notices.
All notices and other communications required or permitted under this Agreement shall be in writing and shall be delivered personally
by hand or by overnight courier, mailed by United States first-class mail, postage prepaid, sent by facsimile or sent by electronic
mail directed (a) if to an Investor, at such Investor’s address, facsimile number or electronic mail address set forth in
the Company’s records, or at such other address, facsimile number or electronic mail address as such Investor may designate
by ten (10) days’ advance written notice to the other parties hereto or (b) if to the Company, to its address, facsimile
number or electronic mail address set forth on its signature page to this Agreement and directed to the attention of its President,
or at such other address, facsimile number or electronic mail address as the Company may designate by ten (10) days’ advance
written notice to the other parties hereto. All such notices and other communications shall be effective or deemed given upon
delivery, on the date that is three (3) days following the date of mailing, upon confirmation of facsimile transfer or upon confirmation
of electronic mail delivery.

 

    	 

     

    

 

3.7 Interpretation.
The words “include,” “includes” and “including” when used herein shall be deemed in each case
to be followed by the words “without limitation.” The titles and subtitles used in this Agreement are used for convenience
only and are not considered in construing or interpreting this Agreement.

 

3.8 Severability.
If one or more provisions of this Agreement are held to be unenforceable under applicable law, such provision shall be excluded
from this Agreement, and the balance of the Agreement shall be interpreted as if such provision were so excluded, and shall be
enforceable in accordance with its terms.

 

3.9 Independent
Nature of Investors’ Obligations and Rights. The obligations of each Investor hereunder are several and not joint with
the obligations of any other Investor hereunder, and no Investor shall be responsible in any way for the performance of the obligations
of any other Investor hereunder. Nothing contained herein or in any other agreement or document delivered at any closing, and
no action taken by any Investor pursuant hereto or thereto, shall be deemed to constitute the Investors as a partnership, an association,
a joint venture or any other kind of entity, or create a presumption that the Investors are in any way acting in concert with
respect to such obligations or the transactions contemplated by this Agreement. Each Investor shall be entitled to protect and
enforce its rights, including without limitation the rights arising out of this Agreement, and it shall not be necessary for any
other Investor to be joined as an additional party in any proceeding for such purpose.

 

3.10 Counterparts.
This Agreement may be executed in any number of counterparts, each of which shall be an original, but all of which together shall
constitute one instrument.

 

3.11 Telecopy Execution
and Delivery. A facsimile, telecopy or other reproduction of this Agreement may be executed by one or more parties hereto,
and an executed copy of this Agreement may be delivered by one or more parties hereto by facsimile or similar electronic transmission
device pursuant to which the signature of or on behalf of such party can be seen, and such execution and delivery shall be considered
valid, binding and effective for all purposes. At the request of any party hereto, all parties hereto agree to execute an original
of this Agreement as well as any facsimile, telecopy or other reproduction hereof.

 

[SIGNATURE PAGE FOLLOWS]

 

    	 

     

    

 

 

IN WITNESS WHEREOF,
the Company has caused this Agreement to be executed by its duly authorized officer, as of the date, month and year first set forth
above.

 

	 	SEVION THERAPEUTICS, INC.
	 	 	 
	 	By:	 
	 	Name: 	 
	 	Title:	 
	 	 	 
	 	Address for notice:

 

[COMPANY SIGNATURE PAGE TO REGISTRATION
RIGHTS AGREEMENT]

 

    	 

     

    

 

IN WITNESS
WHEREOF, the undersigned Investor has executed this Agreement as of the date, month and year that such Investor became the owner
of Registrable Securities.

 

		“Investor”	 
	 	 	 
	 	 	 
	 	By:	 
	 	Name 	 
	 	Title:  	 
	 	 	 
	 	Address:	 
	 	 	 
	 	 	 
	 	 	 
	 	 	 
	 	Telephone:	 
	 	 	 
	 	Facsimile:	 
	 	 	 
	 	Email:	 

 

[INVESTOR COUNTERPART SIGNATURE PAGE
TO

REGISTRATION RIGHTS AGREEMENT]

 

    	 

     

    

 

Annex A

 

Plan of Distribution

 

Each selling stockholder
of the common stock and any of their pledgees, assignees and successors-in-interest may, from time to time, sell any or all of
their shares of common stock on the Over-the-Counter Bulletin Board or any other stock exchange, market or trading facility on
which the shares are traded or in private transactions. These sales may be at fixed or negotiated prices. A selling stockholder
may use any one or more of the following methods when selling shares:

 

		·	ordinary brokerage transactions and transactions in which the broker-dealer solicits purchasers;

 

		·	block trades in which the broker-dealer will attempt to sell the shares as agent but may position and resell a portion of the
block as principal to facilitate the transaction;

 

		·	purchases by a broker-dealer as principal and resale by the broker-dealer for its account;

 

		·	an exchange distribution in accordance with the rules of the applicable exchange;

 

		·	privately negotiated transactions;

 

		·	settlement of short sales entered into after the effective date of the registration statement of which this prospectus is a
part;

 

		·	broker-dealers may agree with the selling stockholders to sell a specified number of such shares
at a stipulated price per share;

 

		·	through the writing or settlement of options or other hedging transactions, whether through an options exchange or otherwise;

 

		·	a combination of any such methods of sale; or

 

		·	any other method permitted pursuant to applicable law.

 

The selling stockholders
may also sell shares under Rule 144 under the Securities Act of 1933, as amended, if available, rather than under this prospectus.

 

Broker-dealers engaged
by the selling stockholders may arrange for other brokers-dealers to participate in sales. Broker-dealers may receive commissions
or discounts from the selling stockholders (or, if any broker-dealer acts as agent for the purchaser of shares, from the purchaser)
in amounts to be negotiated, but, except as set forth in a supplement to this prospectus, in the case of an agency transaction
not in excess of a customary brokerage commission in compliance with FINRA Rule 2440; and in the case of a principal transaction
a markup or markdown in compliance with FINRA IM-2440.

 

    	 

     

    

  

In connection with
the sale of the common stock or interests therein, the selling stockholders may enter into hedging transactions with broker-dealers
or other financial institutions, which may in turn engage in short sales of the common stock in the course of hedging the positions
they assume. The selling stockholders may also sell shares of the common stock short and deliver these securities to close out
their short positions, or loan or pledge the common stock to broker-dealers that in turn may sell these securities. The selling
stockholders may also enter into option or other transactions with broker-dealers or other financial institutions or the creation
of one or more derivative securities which require the delivery to such broker-dealer or other financial institution of shares
offered by this prospectus, which shares such broker-dealer or other financial institution may resell pursuant to this prospectus
(as supplemented or amended to reflect such transaction).

 

The selling stockholders
and any broker-dealers or agents that are involved in selling the shares may be deemed to be “underwriters” within
the meaning of the Securities Act of 1933, as amended, in connection with such sales. In such event, any commissions received by
such broker-dealers or agents and any profit on the resale of the shares purchased by them may be deemed to be underwriting commissions
or discounts under the Securities Act of 1933, as amended. Each selling stockholder has informed us that it does not have any written
or oral agreement or understanding, directly or indirectly, with any person to distribute the common stock.

 

We are required to
pay certain fees and expenses incurred by us incident to the registration of the shares. We have agreed to indemnify the selling
stockholders against certain losses, claims, damages and liabilities, including liabilities under the Securities Act of 1933, as
amended.

 

Because selling stockholders
may be deemed to be “underwriters” within the meaning of the Securities Act of 1933, as amended, they will be subject
to the prospectus delivery requirements of the Securities Act of 1933, as amended, including Rule 172 thereunder. In addition,
any securities covered by this prospectus which qualify for sale pursuant to Rule 144 under the Securities Act of 1933, as amended
may be sold under Rule 144 rather than under this prospectus. There is no underwriter or coordinating broker acting in connection
with the proposed sale of the resale shares by the selling stockholders.

 

We agreed to keep this
prospectus effective until the earlier of (i) the date on which the shares may be resold by the selling stockholders without registration
and without the requirement to be in compliance with Rule 144(c)(1) and otherwise without restriction or limitation pursuant to
Rule 144 or (ii) all of the shares have been sold pursuant to this prospectus or Rule 144 under the Securities Act or any other
rule of similar effect. The resale shares will be sold only through registered or licensed brokers or dealers if required under
applicable state securities laws. In addition, in certain states, the resale shares may not be sold unless they have been registered
or qualified for sale in the applicable state or an exemption from the registration or qualification requirement is available and
is complied with.

 

Under applicable rules
and regulations under the Securities Exchange Act of 1934, as amended, any person engaged in the distribution of the resale shares
may not simultaneously engage in market making activities with respect to the common stock for the applicable restricted period,
as defined in Regulation M, prior to the commencement of the distribution. In addition, the selling stockholders will be subject
to applicable provisions of the Securities Exchange Act of 1934, as amended, and the rules and regulations thereunder, including
Regulation M, which may limit the timing of purchases and sales of shares of the common stock by the selling stockholders or any
other person. We will make copies of this prospectus available to the selling stockholders and have informed them of the need to
deliver a copy of this prospectus to each purchaser at or prior to the time of the sale (including by compliance with Rule 172
under the Securities Act of 1933, as amended).

 

    	 

     

    

 

Annex B

 

Selling Securityholder Notice
and Questionnaire

 

The undersigned beneficial owner of common
stock (the “Registrable Securities”) of Sevion Therapeutics, Inc., a Delaware corporation (the “Company”),
understands that the Company has filed or intends to file with the Securities and Exchange Commission (the “Commission”)
a registration statement (the “Registration Statement”) for the registration and resale under Rule 415 of the
Securities Act of 1933, as amended (the “Securities Act”), of the Registrable Securities, in accordance with
the terms of the Registration Rights Agreement (the “Registration Rights Agreement”) to which this document
is annexed. A copy of the Registration Rights Agreement is available from the Company upon request at the address set forth below.
All capitalized terms not otherwise defined herein shall have the meanings ascribed thereto in the Registration Rights Agreement.

 

Certain legal consequences arise from being
named as a selling securityholder in the Registration Statement and the related prospectus. Accordingly, holders and beneficial
owners of Registrable Securities are advised to consult their own securities law counsel regarding the consequences of being named
or not being named as a selling securityholder in the Registration Statement and the related prospectus.

 

NOTICE

 

The undersigned beneficial owner (the “Selling
Securityholder”) of Registrable Securities hereby elects to include the Registrable Securities owned by it in the Registration
Statement.

 

The undersigned hereby provides the following
information to the Company and represents and warrants that such information is accurate:

 

QUESTIONNAIRE

 

1.          Name.

 

(a)          Full
Legal Name of Selling Securityholder 

 

	 

 

(b)          Full
Legal Name of Registered Holder (if not the same as (a) above) through which Registrable Securities are held: 

 

	 

 

(c)          Full
Legal Name of Natural Control Person (which means a natural person who directly or indirectly alone or with others has power to
vote or dispose of the securities covered by this Questionnaire):

 

    	 

     

    

 

2.          Address
for Notices to Selling Securityholder:

	 
	  

	 

 

Telephone:

Fax:

Contact Person:

 

3.          Broker-Dealer
Status:

 

(a)          Are
you a broker-dealer?

 

		Yes	No

 

(b)          If
“yes” to Section 3(a), did you receive your Registrable Securities as compensation for investment banking services
to the Company?

 

		Yes	No

 

Note: If “no” to Section 3(b),
the Commission’s staff has indicated that you should be identified as an underwriter in the Registration Statement.

 

(c)          Are
you an affiliate of a broker-dealer?

 

		Yes	No

 

(d)          If
you are an affiliate of a broker-dealer, do you certify that you purchased the Registrable Securities in the ordinary course of
business, and at the time of the purchase of the Registrable Securities to be resold, you had no agreements or understandings,
directly or indirectly, with any person to distribute the Registrable Securities?

 

		Yes	No

 

Note: If “no” to Section 3(d),
the Commission’s staff has indicated that you should be identified as an underwriter in the Registration Statement.

 

4. Beneficial Ownership of Securities of the Company Owned
by the Selling Securityholder.

 

Except as set forth below in this Item
4, the undersigned is not the beneficial or registered owner of any securities of the Company other than the securities issuable
pursuant to the Subscription Agreement.

 

    	 

     

    

 

(a)          Type
and Amount of other securities beneficially owned by the Selling Securityholder: 

 

	 
	 

 

5. Relationships with the Company:

 

Except as set forth below, neither the
undersigned nor any of its affiliates, officers, directors or principal equity holders (owners of 5% of more of the equity securities
of the undersigned) has held any position or office or has had any other material relationship with the Company (or its predecessors
or affiliates) during the past three years.

 

State any exceptions here:

 

 

 

 

 

 

The undersigned agrees to promptly notify the Company of any inaccuracies
or changes in the information provided herein that may occur subsequent to the date hereof at any time while the Registration Statement
remains effective.

 

By signing below, the undersigned consents
to the disclosure of the information contained herein in its answers to Items 1 through 5 and the inclusion of such information
in the Registration Statement and the related prospectus and any amendments or supplements thereto. The undersigned understands
that such information will be relied upon by the Company in connection with the preparation or amendment of the Registration Statement
and the related prospectus.

 

IN WITNESS WHEREOF the undersigned, by
authority duly given, has caused this Notice and Questionnaire to be executed and delivered either in person or by its duly authorized
agent.

 

Date:

 

	 	Beneficial Owner:
	 	 
	 	By:	 
	 	 	Name:
	 	 	Title:

 

[SIGNATURE PAGE FOR SELLING
SECURITYHOLDER NOTICE AND QUESTIONNAIRE]

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