Document:

Exhibit 10.1

 

THE SECURITIES REPRESENTED HEREBY
(THE “SECURITIES”) HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”),
OR ANY STATE SECURITIES LAWS AND MAY NOT BE SOLD, ASSIGNED, TRANSFERRED, PLEDGED, ENCUMBERED, HYPOTHECATED, EXCHANGED OR OTHERWISE
DISPOSED OF UNLESS REGISTERED UNDER THE SECURITIES ACT AND UNDER APPLICABLE STATE SECURITIES LAWS OR THE COMPANY SHALL HAVE RECEIVED
AN OPINION OF COUNSEL FOR THE HOLDER, REASONABLY SATISFACTORY TO THE COMPANY AND ITS COUNSEL, THAT REGISTRATION OF SUCH SECURITIES
UNDER THE SECURITIES ACT AND UNDER THE PROVISIONS OF APPLICABLE STATE SECURITIES LAWS IS NOT REQUIRED. 

 

CONVERTIBLE PROMISSORY NOTE

 

	$[NUMBER]	[DATE]

 

For value received,
Humanigen, Inc., a Delaware corporation (the “Company”), promises to pay to [HOLDER NAME] or its assigns
(the “Holder”) the principal sum of $[NUMBER] together with accrued and unpaid interest thereon, each
due and payable on the date and in the manner set forth below.

 

This convertible promissory
note (this “Note”) is issued as part of a series of similar convertible promissory notes (collectively,
the “Notes”) pursuant to the terms of that certain Convertible Note Purchase Agreement dated as of [DATE],
by and among the Company, Holder, and the other purchasers identified therein, as the same may be amended from time to time (the
“Agreement”). Capitalized terms used but not otherwise defined herein shall have the meanings ascribed
to them in the Agreement. This Note is an unsecured obligation of the Company.

 

1.       Repayment.
Unless otherwise converted as provided herein, all unpaid principal together with the unpaid and accrued interest payable hereunder
shall be due and payable on the date repayment by the Holder is demanded which may be any day on or after the earliest of (i) twenty-four
months from the date of this Note, (ii) the occurrence of an Event of Default (as described in Section 7 below), or (iii) the occurrence
of a Liquidation Event (the earliest date of which being the “Maturity Date”). “Liquidation
Event” means (i) any event pursuant to which (A) any Person or Persons acting as a group acquires all or substantially
all of the assets of the Company by sale, exclusive license or otherwise, or (B) any Person or Persons acting as a group (other
than the equity holders of the Company existing as of the date hereof), whether by merger, consolidation or otherwise, shall become
the beneficial owner(s) of greater than an aggregate of 50% of the Company’s outstanding voting equity interests (other than
in connection with a Qualified Financing (as defined below) or Non-Qualified Financing (as defined below)), or (ii) any dissolution
or winding-up of the Company. This Note shall rank pari passu with each of the other Notes such that all Notes shall rank
equally and no payment will be made under any Note unless a pro rata payment is simultaneously made under all Notes.

 

2.       Interest
Rate. The Company promises to pay simple interest on the outstanding principal amount hereof from the date hereof until payment
in full, which interest shall be payable at the rate of 7% per annum or the maximum rate permissible by law, whichever is less.
Interest shall be due and payable on the Maturity Date and shall be calculated on the basis of a 365-day year for the actual number
of days elapsed.

 

    			 

     

    

 

3.       Conversion.

 

(a)       Mandatory
Conversion Upon Qualified Financing. If the Company issues and sells its Equity Securities (as defined below) to investors
(the “Qualified Financing Investors”) on or before the date of the repayment in full of this Note in
any bona fide financing transaction that results in gross proceeds to the Company of at least $10,000,000 (excluding conversion
of this Note and other indebtedness), (a “Qualified Financing”), then the Company will give the Holder
at least ten days’ prior written notice of the anticipated closing date of such Qualified Financing, and the outstanding
principal balance and any unpaid accrued interest of this Note (the “Conversion Amount”) will automatically
be converted, upon such closing date, into into either (x) such Equity Securities as the Holder would acquire if the Conversion
Amount were invested directly in the Qualified Financing on the same terms and conditions as given to the Qualified Financing Investors,
or (y) Common Stock at a conversion price equal to $0.45 per share (subject to ratable adjustment for any stock split, stock dividend,
stock combination or other recapitalization occurring subsequent to the date of this Note), as each Holder shall elect and notify
the Company at least five days prior to the anticipated closing date of such Qualified Financing. For purposes of this Note, “Equity
Securities” shall mean Common Stock or any securities issued by the Company (other than convertible indebtedness)
and conferring the right to purchase Common Stock or that are convertible into or exercisable or exchangeable for (with or without
additional consideration) Common Stock, whether sold independently or as part of a unit of one or more securities issued by the
Company.

 

(b)       Optional
Conversion Upon Non-Qualified Financing. In the event that the Company issues and sells shares of its Equity Securities to
investors (the “Non-Qualified Financing Investors”) on or before the date of the repayment in full of
this Note in any bona fide financing transaction that is not a Qualified Financing (a “Non-Qualified
Financing”), then the Company will give the Holders at least ten days’ prior written notice of the anticipated
closing date of such Non-Qualified Financing and each of the Holders may elect to convert, upon such closing date either (x), all,
but not less than all, of the Conversion Amount of the Notes held by such Holder into such Equity Securities as the Holder would
acquire if the Conversion Amount were invested directly in the Non-Qualified Financing on the same terms and conditions as given
to the Non-Qualified Financing Investors, or (y) Common Stock at a conversion price equal to $0.45 per share (subject to ratable
adjustment for any stock split, stock dividend, stock combination or other recapitalization occurring subsequent to the date of
this Note). In order to exercise the option to convert this Note pursuant to this Section 3(b), each Holder must notify the Company
of the Holder’s election to so convert at least five days prior to the anticipated closing date of the Non-Qualified Financing.

 

(c)       Optional
Conversion Upon Liquidation Event. In the event that the Company enters into any agreement providing for, or publicly announces
the intention to consummate, a Liquidation Event prior to the conversion or repayment in full of this Note, (i) the Company will
give the Holder at least ten days’ prior written notice of the anticipated closing date of such Liquidation Event, and (ii)
the Holder may elect to convert, upon such closing date, all, but not less than all, of the Conversion Amount into Common Stock
at a conversion price equal to $0.45 per share (subject to ratable adjustment for any stock split, stock dividend, stock combination
or other recapitalization occurring subsequent to the date of this Note). In order to exercise the option to convert the Notes
pursuant to this Section 3(c), the Holder must notify the Company of the Holder’s election to so convert or require payment
at least five days prior to the anticipated closing date of the Liquidation Event.

 

(d)       No
fractional units will be issued on conversion of this Note. If the Holder would otherwise be entitled to a fractional unit, the
Holder shall receive in lieu thereof a cash payment equal to the applicable per unit price of the Equity Securities or Common Stock
into which the Conversion Amount is proposed to be converted, multiplied by the fraction of the unit the Holder would otherwise
be entitled to receive.

 

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4.       Maturity.
If this Note has not been previously converted pursuant to Section 3 above, then, effective upon the Maturity Date, the Holders
may elect to convert the Conversion Amount of the Notes into Common Stock at a conversion price equal to $0.45 per share (subject
to ratable adjustment for any stock split, stock dividend, stock combination or other recapitalization occurring subsequent to
the date of this Note). Any election to convert the Notes pursuant to this paragraph must be made in writing and delivered to the
Company at least five days prior to the Maturity Date. Unless this Note has been previously converted in accordance with the terms
of Section 3 above or pursuant to the preceding sentences of this Section 4, the entire outstanding principal balance and all unpaid
accrued interest shall become fully due and payable on the Maturity Date.

 

5.       Expenses.
 In the event of any default hereunder, the Company shall pay all reasonable attorneys’ fees and court costs incurred
by the Holder in enforcing and collecting this Note.

 

6.       Prepayment.
The Company may not prepay this Note (including accrued interest), in whole or in part, prior to the Maturity Date without the
consent of the Holder.

 

7.       Default.
If there shall be any Event of Default (as defined below) hereunder, at the option and upon the declaration of the Holder and
upon written notice to the Company (which election and notice shall not be required in the case of an Event of Default under Section
7(c), 7(d) or 7(e)), this Note shall accelerate and all principal and unpaid accrued interest shall become due and payable. The
occurrence of any one or more of the following shall constitute an “Event of Default”:

 

(a)       The
Company fails to pay timely any of the principal amount due under this Note on the date the same becomes due and payable or any
accrued interest or other amounts due under this Note on the date the same becomes due and payable;

 

(b)       The
Company shall default in its performance of any covenant under the Agreement or this Note, and such default is not cured by the
Company within 30 days after written notice thereof is given to the Company by the Holder;

 

(c)       The
Company files any petition or action for relief under any bankruptcy, reorganization, insolvency or moratorium law or any other
law for the relief of, or relating to, debtors, now or hereafter in effect, or makes any assignment for the benefit of creditors
or takes any corporate action in furtherance of any of the foregoing;

 

(d)       An
involuntary petition is filed against the Company (unless such petition is dismissed or discharged within 60 days) under any bankruptcy
statute now or hereafter in effect, or a custodian, receiver, trustee, assignee for the benefit of creditors (or other similar
official) is appointed to take possession, custody or control of any property of the Company;

 

(e)       A
liquidation, termination of existence or dissolution of the Company; or

 

(f)       Any
representation, warranty or statement of fact made by the Company in the Agreement, or any other agreement, schedule, confirmatory
assignment or otherwise in connection with the transactions contemplated hereby or thereby, shall when made or deemed made be false
or misleading in any material respect; provided, however, that such failure shall not result in an Event of Default to the extent
it is corrected by the Company within a period of 30 days after the Company’s receipt of written notice from the Holder specifying
such failure.

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8.       Waiver.
The Company hereby waives demand, notice, presentment, protest and notice of dishonor.

 

9.       Notices.
All notices, requests, demands, consents, instructions or other communications required or permitted hereunder shall be in writing
and faxed, emailed, mailed or delivered to each party as follows: (i) if to the Holder, at the Holder’s address, email address
or facsimile number set forth in the Agreement, or at such other address, email address or facsimile number as the Holder shall
have furnished the Company in writing, or (ii) if to the Company, at the Company’s address, email address or facsimile number
set forth on the signature page to the Agreement, or at such other address, email address or facsimile number as the Company shall
have furnished to the Holder in writing. All such notices and communications will be deemed effectively given the earliest of (a)
when received, (b) when delivered personally, (c) one business day after being delivered by facsimile or email (with receipt of
appropriate confirmation), (d) one business day after being deposited with an overnight courier service of recognized standing
or (e) three days after being deposited in the U.S. mail, first class with postage prepaid.

 

10.       Governing
Law. This Note shall be governed by and construed under the internal laws of the State of New York, without giving effect to
conflicts of laws principles.

 

11.       Modification;
Waiver. Any term of this Note may be amended or waived with the written consent of the Company and the Holder. In
the event that the Company amends or otherwise modifies any other of the Notes, the Company shall give notice thereof to the Holder
and, upon request by the Holder, this Note shall be similarly amended or modified.

 

12.       Powers
and Remedies Cumulative; Delay or Omission Not Waiver of Default. No right or remedy herein conferred upon or reserved to the
Holder is intended to be exclusive of any other right or remedy, and every right and remedy shall, to the extent permitted by law,
be cumulative and in addition to every other right and remedy given hereunder or now or hereafter existing at law or in equity
or otherwise. The assertion or employment of any right or remedy hereunder, or otherwise, shall not prevent the concurrent assertion
or employment of any other appropriate right or remedy. No delay or omission of the Holder to exercise any right or power accruing
upon any Event of Default occurring and continuing as aforesaid shall impair any such right or power or shall be construed to be
a waiver of any such Event of Default or an acquiescence therein; and every power and remedy given by this Note or by law may be
exercised from time to time, and as often as shall be deemed expedient, by the Holder.

 

13.       Transfer
Rights. The Holder may not transfer this Note to a third party without the prior written consent of the Company, not to be
unreasonably withheld, conditioned or delayed; provided, however, that the Holder shall have the right to transfer and assign this
Note without any consent of the Company to a Permitted Transferee (as defined below). Each new Note issued upon any transfer of
this Note shall bear a legend as to the applicable restrictions on transferability to ensure compliance with the Act, unless in
the opinion of counsel for the Company such legend is not required in order to ensure compliance with the Act. The Company may
issue stop transfer instructions to its Transfer Agent, if any, in connection with such restrictions. Subject to the foregoing,
transfers of this Note shall be registered upon registration books maintained for such purpose by or on behalf of the Company.
Prior to presentation of this Note for registration of transfer, the Company shall treat the registered holder hereof as the owner
and holder of this Note for the purpose of receiving all payments of principal and interest hereon and for all other purposes whatsoever,
whether or not this Note shall be overdue and the Company shall not be affected by notice to the contrary. “Permitted
Transferee” means, as to any Holder, any of the following: (i) if a natural person, his/her ancestors, descendants,
siblings, or spouse, any executor or administrator of his/her estate, or to a custodian, trustee (including a trustee of a voting
trust), executor, or other fiduciary primarily for the account of such Holder or his/her ancestors, descendants, siblings, or spouse,
whether step, in-law or adopted, and, in the case of any such trust or fiduciary, to the Holder who transferred this Note to such
trust or fiduciary, but only with respect to transfers made for bona fide estate planning purposes, either during his or her lifetime
or on death by will or intestacy; (ii) with respect to any Holder which is an entity, (A) the then-existing members, shareholders
or other investors in the Holder in connection with the dissolution or winding-up of the Holder, or (B) any Person in connection
with any consolidation or reorganization of the Holder directly or indirectly with or into one or more other investment vehicles;
or (iii) any affiliate of the Holder (other than any investment portfolio company of the Holder that is an affiliate) which controls,
is controlled by or is under common control with the Holder.

 

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14.       Most
Favored Nation Amendment Provisions. Prior to the conversion or payment in full of the Note, if the Company issues any indebtedness
which is convertible into the Company’s Equity Securities (“Subsequent Convertible Securities”),
the Company will promptly provide Holder with written notice thereof, together with a copy of all documentation relating to such
Subsequent Convertible Securities and, upon written request of Holder, any additional information related to such Subsequent Convertible
Securities as may be reasonably requested by Holder. Within 30 days after the Holder’s receipt of such information,
if the Holder determines that the terms of the Subsequent Convertible Securities are preferable to the terms of the Note, Holder
will notify the Company in writing. Promptly after receipt of such written notice from the Holder, the Company agrees to amend
and restate the Note to be identical to the instruments evidencing the Subsequent Convertible Securities and any purchase documents
related thereto.

 

15.       Assignment
by the Issuer. Neither this Note nor any of the rights, interests or obligations hereunder may be assigned, in whole or in
part, by the Company, without the prior written consent of the Holder.

 

16.       Successors
and Assigns. Subject to the restrictions on transfer provided herein, the rights and obligations of the Company and the Holder
shall be binding upon and benefit the respective successors, assigns, heirs, administrators and transferees of the Company or the
Holder, as applicable.

 

ORAL AGREEMENTS OR
COMMITMENTS TO LOAN MONEY, EXTEND CREDIT OR TO FORBEAR FROM ENFORCING REPAYMENT OF A DEBT INCLUDING PROMISES TO EXTEND OR RENEW
SUCH DEBT ARE NOT ENFORCEABLE. TO PROTECT YOU (BORROWER(S)) AND US (CREDITOR) FROM MISUNDERSTANDING OR DISAPPOINTMENT, ANY AGREEMENTS
WE REACH COVERING SUCH MATTERS ARE CONTAINED IN THIS WRITING, WHICH IS THE COMPLETE AND EXCLUSIVE STATEMENT OF THE AGREEMENT BETWEEN
US, EXCEPT AS WE MAY LATER AGREE IN WRITING TO MODIFY IT.

 

[Remainder of Page
Intentionally Left Blank]

 

 

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IN WITNESS WHEREOF,
the Company has caused this Convertible Promissory Note to be issued as of the date first set forth above.

 

	 	
        COMPANY:

         

        HUMANIGEN, INC.

        

        

         

         

        By:/s/ Cameron Durrant

        Name: Dr. Cameron Durrant

        Title: Chief Executive Officer

 

[Signature Page to Convertible Promissory
Note]Exhibit 10.2

 

 

EMPLOYMENT AGREEMENT (“Agreement”),
as of August 22, 2018, by and between Humanigen, Inc., a Delaware corporation with offices at 533 Airport Blvd, Suite 400, Burlingame,
CA 94010 (the “Corporation”), and Jon G. Jester, an individual (“Executive”).

 

W I T N E S S E T H

 

WHEREAS, the Corporation desires to
employ Executive as its Chief Financial Officer upon the terms and conditions hereinafter set forth; and

 

WHEREAS, Executive desires to serve
as the Chief Financial Officer of the Corporation upon the terms and conditions hereinafter set forth.

 

NOW, THEREFORE, the parties mutually
agree as follows:

 

Section 1.      Employment. Commencing
on August 22, 2018 (hereinafter referred to as the “Effective Date”), the Corporation shall employ Executive and Executive
shall commence such employment, as an executive of the Corporation, on the terms and conditions set forth in this Agreement.

Section
2.      Duties. As of the Effective Date, Executive shall serve as Chief Financial Officer of the Corporation. The
duties and services required to be performed are described in the job description previously provided to you and shall be consistent
with your position and as may be assigned from time to time by the President
and Chief Executive Officer and the Corporation’s Board of Directors (the “Board”). From and after the Effective
Date and during the term of this Agreement, Executive shall devote substantially all of his business time to the performance of
his duties hereunder unless otherwise authorized by the Board; provided, that Executive may not serve on any public company outside
boards without the prior written consent of the Board.

 

Section 3.      Term. This Agreement
shall become effective as of the date written above (the "Effective Date") and shall terminate three (3) years from the
Effective Date of this Agreement; provided, however, that this Agreement shall remain in effect for successive one year periods
thereafter unless, not less than six (6) months prior to the scheduled expiration of the term of this Agreement, either you or
the Company shall deliver to the other written notice of his, her or its intention not to continue in effect this Agreement, in
which case this Agreement shall terminate as of the scheduled expiration date of the year in which such notice is given; and provided
further, that the Agreement is not otherwise terminated as provided below (the "Term").

 

    			 

     

    

 

Section 4.      Compensation
of Executive.

4.1.       Compensation.
As compensation for his services hereunder the Corporation shall pay Executive an annual salary (“Salary”) equal
to Three Hundred Ten Thousand ($310,000) Dollars. The Salary shall be payable according to the salary payment cycle of the Corporation,
less such deductions as shall be required to be withheld by applicable law and regulations. Upon each anniversary of the Effective
Date during the term of this Agreement, Executive’s Salary shall be reviewed by the Compensation Committee of the Board (the
“Compensation Committee”), or earlier at the sole discretion of the Compensation Committee and the Board.

4.2.       Bonus;
Stock Options.

 

(a)       In
addition to his Salary, Executive may receive a cash or cash equivalent bonus (“Bonus”) in respect of each calendar
year during the Term.  The Bonus for each calendar year shall be determined by the Compensation Committee and the Board in
their sole discretion. The Target Bonus shall be fifty percent (50%) of the Salary in any one year, with a maximum amount at the
sole discretion of the Compensation Committee and the Board. Such Bonus may be a mix of cash and stock, as determined by the Board
in its sole discretion. Objectives for the Bonus will be set and agreed to by the Board and Executive at the beginning of each
calendar year. The Bonus for any particular calendar year, if any, will be paid by March 15 of the following calendar year.

 

(b)       Subject
to Compensation Committee and Board approval, Executive shall be eligible to receive, as promptly as possible following the Effective
Date, an option to purchase one hundred and fifty thousand (150,000) shares of the Corporation’s Common Stock, subject to
and in accordance with the terms and provisions of the Corporation’s 2012 Equity Incentive Plan, as amended (the “Plan”)
and the applicable award agreement. Such stock options will vest quarterly over three years in equal installments.

 

(c)       Subject
to Compensation Committee and Board approval, for each fiscal year during the term of his employment following the first fiscal
year, Executive may be eligible to receive, at such time as the Compensation Committee and Board may deem appropriate, options
to purchase additional shares of the Corporation’s Common Stock in accordance with the terms and provisions of the Plan or
any successor plan.

 

4.3.       Expenses.
The Corporation shall pay or reimburse Executive for all reasonable and necessary business, travel or other expenses incurred by
him, upon proper documentation thereof, in accordance with the Corporation’s travel and expense policy, which may be incurred
by him in connection with the rendition of the services contemplated hereunder.

 

4.4.       Benefits.
From and after the Effective Date and during the Term, Executive shall be entitled to participate in such pension, profit sharing,
group insurance, term life, option plans, hospitalization, and group health benefit plans and all other benefits and plans as the
Corporation provides to its senior executives, subject to the terms and conditions of such plans.

 

    			 

     

    

 

4.5.       Vacations.
Executive shall be entitled to vacation time in accordance with the Corporation’s vacation time policy.

 

4.6.       Sick
Time. Executive shall be entitled to sick time in accordance with the Corporation’s sick time policy.

Section 5.        Termination.

 

5.1.       Termination.
This Agreement and Executive’s employment hereunder shall terminate immediately upon: (i) Executive’s death or Total
Disability (as defined below); or (ii) termination of Executive’s employment by the Corporation For Cause (as defined below);
or (iii) termination of Executive’s employment by the Corporation other than For Cause; or (iv) a Change in Control Termination
(as defined below); or (v) termination of Executive’s employment by Executive without Good Reason (as defined below); or
(vi) termination of Executive’s employment by Executive for Good Reason.

 

5.2.       Termination
Upon Death or Total Disability. In the event of a termination upon the death or Total Disability of Executive, the Corporation
shall pay to Executive, or any person designated by Executive in writing or, if no such person is designated, to his estate, the
Salary which has been earned but unpaid. As used herein, the term “Total Disability” shall mean that Executive is unable
to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment which can be
expected to result in death or which has lasted, or can be expected to last, for a continuous period of not less than one year.

 

5.3.       Termination
For Cause or without Good Reason. In the event Executive’s employment is terminated by the Corporation For Cause or by
Executive without Good Reason, Executive shall be paid his Salary through the date of termination. As used herein, the term “For
Cause” shall mean (i) Executive’s failure to perform Executive’s material duties hereunder (other than such failure
resulting from incapacity due to physical or mental illness); (ii) Executive’s substantiated misappropriation of the Corporation’s
assets or substantiated perpetration of fraud against or proven dishonesty in dealings with the Corporation; (iii) Executive’s
plea of guilty or nolo contendere to, or conviction in a court of law of, any crime or offense which constitutes a felony, in each
case whether or not involving the Corporation; (iv) Executive’s willful misconduct; (v) Executive’s habitual drunkenness
or habitual use of illegal substances; (vi) Executive’s failure to cooperate with a governmental or regulatory investigation
concerning the Corporation or Executive; (vii) Executive’s behavior which is materially detrimental to the Corporation’s
reputation; (viii) Executive’s willful refusal to follow, or reckless disregard of, the policies and directives of the Corporation
or the Board; or (ix) Executive’s material breach of this Agreement, which material breach, if curable, is not cured within
fifteen (15) calendar days after notice thereof by the Corporation. Whether a termination is “For Cause,” as such term
is defined in this Section 5.3, shall be determined by the Board in its sole discretion. For purposes of this Section 5.3, no act
or failure to act by Executive shall be considered “willful” if such act is done by Executive in the good faith belief
that such act is or was in the best interests of the Corporation or one or more of its businesses.

 

    			 

     

    

 

5.4.       Termination
for Good Reason. Executive may terminate this Agreement, upon notice to the Corporation, for Good Reason, which Good Reason
is not remedied by the Corporation within thirty (30) calendar days after notice thereof by Executive. The term “Good Reason”
shall include any of the following, (i) any assignment to Executive of duties inconsistent with Executive’s position of its
Executive Vice President, Chief Financial Officer and Chief Administration Officer or which constitutes a significant reduction
in authority, responsibilities, or status; (ii) any demotion, including, but not limited to, reporting to someone other than the
Chief Executive Officer; (iii) any material reduction in Executive’s base salary, or other benefit plans available to
executive officers of the Corporation, or the level, amount or value of any accrued benefit; or (iv) any attempted reduction of
Executive’s bonus potential which is inconsistent with the provisions of this Agreement.

 

5.5.       Termination
by the Corporation other than For Cause or by Executive for Good Reason. If, other than as set forth in Section 10.1, Executive’s
employment is terminated during the Term by the Corporation other than For Cause or by Executive as a result of Good Reason, then
the Corporation shall pay to Executive after such termination, subject to his execution and non-revocation of the release described
in Section 5.6, severance payments (“Severance”) equal to (i) twelve (12) months of Executive’s Salary for the
year in which the termination for Good Reason occurs plus (ii) the amount of the actual bonus earned by Executive under Section
4.2(a) hereof for the year prior to the year of termination, pro-rated based on the number of days Executive was employed by the
Corporation during the year of termination as compared to the total number of days in such year. The Severance shall be paid in
a lump sum within thirty (30) days after the Release Effective Date (as defined below), less such deductions as shall be required
to be withheld by applicable law and regulations. In addition, if Executive timely and properly elects continuation coverage under
the Consolidated Omnibus Reconciliation Act of 1985 (“COBRA”), then, subject to his execution and non-revocation of
the release described in Section 5.6, the Corporation shall reimburse Executive for the monthly COBRA premium paid by Executive
for Executive and Executive’s eligible dependents. Executive shall be eligible to receive such reimbursement until the earliest
of: (x) the twelve (12) month anniversary of the date of Executive’s termination of employment; (y) the date Executive is
no longer eligible to receive COBRA continuation coverage; or (z) the date on which Executive either receives or becomes eligible
to receive substantially similar coverage from another employer.

 

5.6.       Release.
Executive agrees that, as a condition to receiving the payments and benefits set forth in Section 5.5 or Section 10.1, as applicable,
Executive will execute a release of claims substantially in the form of the release attached hereto as Exhibit A. Within
five business days of the date of Executive’s termination of employment, the Corporation shall deliver to Executive the release
for Executive to execute. Executive will forfeit all rights to the payments and benefits set forth in Section 5.5 or Section 10.1,
as applicable, unless, within sixty (60) days of delivery of the release by the Corporation to Executive, Executive executes and
delivers the release to the Corporation and such release has become irrevocable by virtue of the expiration of the revocation period
without the release having been revoked (the first such date, the “Release Effective Date”). In the event that the
Release Effective Date could occur in one of two taxable years of Executive, the Release Effective Date shall be deemed to occur
on the earliest date in the later such taxable year as otherwise would apply hereunder. The Corporation shall have no obligation
to provide the payments and benefits set forth in Section 5.5 or Section 10.1, as applicable, prior to the Release Effective Date.

 

    			 

     

    

 

Section 6.        Confidential Information;
Restrictive Covenants.

6.1.       Disclosure.
Executive hereby acknowledges that he will acquire confidential information concerning the Corporation, its business, products,
product development, formulas, research and development, know-how, names and contact information of the Corporation’s customers,
suppliers, contract manufacturers, and vendors, and the Corporation’s current and future business plans and that, among other
things, his knowledge of the Corporation’s business will be enhanced through his employment by the Corporation. Executive
acknowledges that such information is of great value to the Corporation, is the sole property of the Corporation, other than those
customers, suppliers, contract manufacturers, and vendors introduced to the Corporation by Executive, and has been and will be
acquired by him in confidence.

6.2.       Confidentiality.
In consideration of the obligations undertaken by the Corporation herein, Executive will not, at any time during or after the Term,
directly or indirectly, use for Executive’s own benefit or any other party’s benefit, or reveal, divulge or make known
to any person, any information which is treated as confidential by the Corporation and not otherwise in the public domain. Confidential
information shall not include information which was previously known by Executive, information which was given to Executive by
any third party under no obligation of confidentiality, or information which Executive is required to disclose as a result of a
governmental investigation or by a court order. Executive agrees that all materials or copies thereof containing confidential information
of the Corporation in Executive’s custody or possession will not, at any time, be removed from the Corporation’s premises
without the prior written consent of the Board. The parties hereto acknowledge that pursuant to 18 USC § 1833(b), an individual
may not be held liable under any criminal or civil federal or state trade secret law for disclosure of a trade secret: (i) made
in confidence to a government official, either directly or indirectly, or to an attorney, solely for the purpose of reporting or
investigating a suspected violation of law or (ii) in a complaint or other document filed in a lawsuit or other proceeding, if
such filing is made under seal. The parties hereto further acknowledge that an individual suing an employer for retaliation based
on the reporting of a suspected violation of law may disclose a trade secret to his or her attorney and use the trade secret information
in the court proceeding, so long as any document containing the trade secret is filed under seal and the individual does not disclose
the trade secret except pursuant to court order.

 

6.3.       Restrictive
Covenants. Executive recognizes that the services to be performed by him hereunder are special, unique and extraordinary. The
parties confirm that it is reasonably necessary for the protection of the Corporation that Executive agrees, and, accordingly,
Executive does hereby agree, that he will not, either on Executive’s own behalf or as an officer, director, stockholder,
partner, principal, consultant, associate, employee, owner, agent, creditor, independent contractor, or co-venturer of any third
party or in any other relationship or capacity, directly or indirectly, at any time during his employment and for the Restricted
Period (as defined below) solicit, induce, persuade or encourage, or attempt to solicit, induce, persuade or encourage, any individual
employed by the Corporation, with whom Executive has worked, to terminate such employee’s position with the Corporation,
whether or not such employee is a full-time or temporary employee of the Corporation and whether or not such employment is pursuant
to a written agreement, for a determined period, or at will. The provisions of this Section 6.3 shall only apply to those individuals
employed by the Corporation at the time of solicitation or attempted solicitation.

 

    			 

     

    

 

6.4.       Restricted
Period. “Restricted Period” shall mean the term following Executive’s employment to last for as long as Executive
receives Severance or his regular Salary and benefits from the Corporation.

 

6.5.       Modification
of Restrictions. If any of the restrictions contained in this Section 6 shall be deemed to be unenforceable by reason
of the extent, duration or geographical scope thereof, or otherwise, then after such restrictions have been reduced so as to be
enforceable, in its reduced form this Section shall then be enforceable in the manner contemplated hereby.

 

Section 7.       Work for Hire.

 

7.1.       Executive
agrees to make full and prompt disclosure to the Corporation of all inventions, improvements, discoveries, methods, developments,
formulas, computer software (and programs and code) and works of authorship, whether or not patentable or copyrightable, which
were or are created, made, conceived or reduced to practice by Executive or under Executive’s direction or jointly with others
during Executive’s employment by the Corporation, whether or not during normal working hours or on the premises of the Corporation
(all of which are collectively referred to in this Agreement as “Developments”).

 

7.2.       Executive
agrees to assign and, by executing this Agreement, Executive does hereby assign, to the Corporation (or to any person or entity
designated by the Corporation) all of Executive’s rights, titles and interests, if any, in and to all Developments and all
related patents, patent applications, copyrights and copyright applications. However, this Section 7.2 shall not apply to Developments
(i) which do not relate to the present or planned business or research and development of the Corporation and (ii) which are made
and conceived by Executive: (A) at a time other than during normal working hours, (B) not on the Corporation’s
premises and (C) not using the Corporation’s tools, devices, equipment or proprietary information. Executive understands
that to the extent that the terms of this Agreement shall be construed in accordance with the laws of any state which precludes
a requirement in an employment agreement to assign certain classes of inventions made by an employee, this Section 7 shall be interpreted
not to apply to any invention which a court rules and/or the Corporation agrees falls within such class or classes. Executive also
agrees to waive all claims to moral and/or equitable rights in any Developments.

 

7.3.       Executive
agrees to cooperate fully with the Corporation, both during and after Executive’s employment with the Corporation, with respect
to the procurement, maintenance and enforcement of copyrights, patents and other intellectual property rights (both in the United
States and foreign countries) relating to Developments. Executive agrees that he will sign all papers, including, without limitation,
copyright applications, patent applications, declarations, oaths, formal assignments, assignments of priority rights, and powers
of attorney, which the Corporation may deem necessary or desirable in order to protect its rights and interests in any Development.
Executive further agrees that if the Corporation is unable, after reasonable effort, to secure Executive’s signature on any
such papers, any executive officer of the Corporation shall be entitled to execute any such papers as Executive’s agent and
attorney-in-fact, and Executive hereby irrevocably designates and appoints each executive officer of the Corporation as Executive’s
agent and attorney-in-fact to execute any such papers on Executive’s behalf, and to take any and all actions as the Corporation
may deem necessary or desirable, in order to protect its rights and interests in any Development, under the conditions described
in this sentence.

    			 

     

    

Section 8.        Conflicts of Interest; Insider
Trading.

8.1.       Conflicts
of Interest. Further, in order to avoid actual or apparent conflicts of interest, except with the Corporation’s consent,
Executive shall not have any direct or indirect ownership or financial interest in any company, person or entity which is: (i)
a service provider to, or vendor of the Corporation; (ii) a customer of the Corporation; or (iii) a competitor of the Corporation.
Executive shall not be deemed to have any direct or indirect ownership or financial interest for any such interest that does not
exceed five (5%) percent of the issued and outstanding voting securities of any class of any corporation whose voting capital stock
is traded on a national securities exchange or in the over-the-counter market.

 

8.2.       General
Requirements. Executive shall observe such lawful policies of the Corporation as may from time to time be in effect.

8.3.       Insider
Trading. Considering that the Corporation is a publicly-traded corporation, Executive hereby agrees that Executive shall comply
with the Corporation’s Insider Trading Policy and any and all federal and state securities laws, including but not limited
to those that relate to non-disclosure of information, insider trading and individual reporting requirements and shall specifically
abstain from discussing the non-public aspects of the Corporation’s business affairs with any individual or group of individuals
(e.g., Internet chat rooms) who does not have a business need to know such information for the benefit of the Corporation. Executive
hereby agrees to immediately notify the Corporation’s Compliance Officer or Chief Financial Officer in accordance with the
Corporation’s Insider Trading Policy prior to Executive’s acquisition or disposition of Corporation’s securities.

Section 9.        Indemnification.

9.1.       Indemnification.
The Corporation hereby agrees to indemnify and hold harmless Executive to the fullest extent permitted by
the Corporation’s Certificate of Incorporation, By-Laws,
the Delaware General Corporation Law or any other applicable law, as any or all may be amended from time to time. Such reimbursements
shall include but not be limited to Executive’s reasonable and necessary out of pocket expenses including attorneys and expert
fees, losses, judgments, claims, and settlement payments and any other such costs and expenses.

 

9.2.       Undertaking.
To the extent that the Corporation advances payment for any fees or expenses to Executive pursuant to this Section 9, such advance
shall be accompanied by a written undertaking by Executive to repay such amounts if it shall be ultimately determined by a court
of competent jurisdiction in a final disposition, that Executive (i) is not entitled to be indemnified by the Corporation or (ii)
that the amount advanced exceeded the indemnification to which he is entitled, in which case the amount of such excess shall be
repaid to the Corporation.

 

    			 

     

    

9.3.       Notice.
As a condition precedent to his right to be indemnified hereunder, Executive shall give the Corporation notice in writing as soon
as practicable of any claim made against him for which indemnity will or could be sought under this Agreement.

9.4.       Cooperation.
Executive shall fully cooperate with the Corporation in connection with any matter, which results in the assertion of a claim by
Executive for indemnification hereunder. The Corporation shall be entitled at its own expense to participate in the defense of
any proceeding, claim or action, or, if it shall elect, to assume such defense, in which event such defense shall be conducted
by counsel chosen by the Corporation, subject to the consent of Executive, which consent shall not be unreasonably withheld or
delayed.

9.5.       Exceptions.
The Corporation shall not be liable under this Agreement to make any payment in connection with any claim:

 

(a)       For
which payment is actually made to Executive under valid and collectable insurance policies, the premiums of which are paid by the
Corporation or any of its affiliates, except in respect of any deductible and excess beyond the amount of payment under such insurance;

 

(b)       For
which Executive is indemnified by the Corporation otherwise than pursuant to this Agreement, provided such amount has previously
been paid to Executive;

(c)       Brought
about or contributed to by the dishonesty of Executive;

 

(d)       For
which Executive fails to cooperate in a criminal or civil investigation involving the claim; and

(e)       By
Executive who acts as a plaintiff suing the Corporation, its affiliates or directors, officers or shareholders of the Corporation
or its affiliates, except with regard to Executive’s successful enforcement of Section 9.1 hereof.

 

9.6.       Survival.
The obligations of the Corporation hereunder will survive (i) any actual or purported termination of this Agreement by the Corporation
or its successors or assigns, whether by operation of law or otherwise, (ii) any change in the Corporation’s Certificates
of Incorporation or By-laws, and (iii) termination of Executive’s services to the Corporation or its affiliates (whether
such services were terminated by the Corporation, such affiliate or Executive), if such claim arises as a result of an occurrence
prior to the termination of this Agreement, whether or not a claim is made or an action or proceeding is threatened or commenced
before or after the actual or purported termination of this Agreement, change in the Corporation’s Certificate of Incorporation
or By-laws, or termination of Executive’s services.

 

    			 

     

    

 

Section 10.      Change
in Control.

 

10.1.       Payment
on Change in Control Termination. The Corporation will provide or cause to be provided to Executive the rights and benefits
described below if, during the Term, within the three (3) month period prior to and the twelve (12) month period following a Change
in Control, (x) Executive terminates his employment for Good Reason, or (y) the Corporation or its successor terminates Executive’s
employment (“Change in Control Termination”); provided however, that a Change in Control Termination shall not include
a termination For Cause or a termination as a result of Executive’s death or Total Disability. In the event of a Change in
Control Termination during the Term, the Corporation shall pay or cause its successor to pay to Executive, in cash, in a lump sum
within thirty (30) days after the Release Effective Date, less such deductions as shall be required to be withheld by applicable
law and regulations, and subject to his execution and non-revocation of the release described in Section 5.6, an amount equal to
one (1) times Executive’s base compensation which equals the sum of the following: (i) Executive’s annual Salary on
the day preceding the Change in Control Termination, plus (ii) an amount equal to the aggregate bonus received by Executive for
the year immediately preceding the Change in Control Termination or if no Bonus had been received, then at minimum fifty percent
(50%) of the Target Bonus. In addition, if Executive timely and properly elects continuation coverage under COBRA, then, subject
to his execution and non-revocation of the release described in Section 5.6, the Corporation shall reimburse Executive for the
monthly COBRA premium paid by Executive for Executive and Executive’s eligible dependents. Executive shall be eligible to
receive such reimbursement until the earliest of: (x) the twelve (12) month anniversary of the date of Executive’s termination
of employment; (y) the date Executive is no longer eligible to receive COBRA continuation coverage; or (z) the date on which Executive
either receives or becomes eligible to receive substantially similar coverage from another employer. In addition, in the event
of a Change in Control Termination, subject to Executive’s execution and non-revocation of the release described in Section
5.6, any and all outstanding stock options held by Executive shall become fully vested and exercisable. Executive shall have six
(6) months to exercise any such stock options following his termination of employment, provided that in no event may Executive
exercise a stock option following the original expiration date of such stock option as set forth in the applicable award agreement.

 

10.2.       Change
in Control Defined. A “Change in Control” shall be deemed to occur upon the earliest to occur after the date of
this Agreement of any of the following events;

 

(a)       Any
“person” (as such term is used in Sections 13(d) and 14(d) of the Securities Exchange Act of 1934, as amended (the
“Exchange Act”)) becomes the “beneficial owner” (as defined in Rule 13d-3 of the Exchange Act), directly
or indirectly, of securities of the Corporation representing more than fifty percent (50%) of the total voting power represented
by the Corporation’s then-outstanding voting securities;

 

(b)       The
consummation of the sale or disposition by the Corporation of all or substantially all of the Corporation’s assets;

 

    			 

     

    

 

(c)       The
consummation of a merger or consolidation of the Corporation with or into any other entity, other than a merger or consolidation
which would result in the voting securities of the Corporation outstanding immediately prior thereto continuing to represent (either
by remaining outstanding or by being converted into voting securities of the surviving entity or its parent) more than fifty percent
(50%) of the total voting power represented by the voting securities of the Corporation or such surviving entity or its parent
outstanding immediately after such merger or consolidation; or

 

(d)       Individuals
who are members of the Board (the “Incumbent Board”) cease for any reason to constitute at least a majority of the
members of the Board over a period of 12 months; provided, however, that if the appointment or election (or nomination for election)
of any new Board member was approved or recommended by a majority vote of the members of the Incumbent Board then still in office,
such new member shall, for purposes of this Plan, be considered as a member of the Incumbent Board.

 

A transaction shall not constitute a Change in Control if its
sole purpose is to change the state of the Corporation’s incorporation or to create a holding company that will be owned
in substantially the same proportions by the persons who held the Corporation’s securities immediately before such transaction.

 

Section 11.     Miscellaneous.

11.1.       Section
409A. The parties intend for the payments and benefits under this Agreement to be exempt from Section 409A of the Internal
Revenue Code (“Section 409A”) or, if not so exempt, to be paid or provided in a manner which complies with the requirements
of such section, and intend that this Agreement shall be construed and administered in accordance with such intention. Any payments
that qualify for the “short-term deferral” exception or another exception under Section 409A shall be paid under the
applicable exception. For purposes of the limitations on nonqualified deferred compensation under Section 409A, each payment of
compensation under this Agreement shall be treated as a separate payment of compensation. All in-kind benefits, reimbursements,
and tax-gross-ups (if any) to be provided under this Agreement shall be made or provided in accordance with the requirements of
Section 409A of the Code, including, where applicable, the requirements that (x) the amount of expenses eligible for reimbursement,
or in kind benefits provided, during a calendar year may not affect the expenses eligible for reimbursement, or in kind benefits
to be provided, in any other calendar year, (y) the reimbursement of an eligible expense will be made no later than the last day
of the calendar year following the year in which the expense is incurred, and (z) the right to reimbursement or in kind benefits
is not subject to liquidation or exchange for another benefit. Notwithstanding anything contained herein to the contrary, to the
extent required in order to avoid accelerated taxation and/or tax penalties under Section 409A, (i) no amounts payable under this
Agreement to Executive on termination of employment shall be paid until Executive would be considered to have incurred a separation
from service from the Corporation within the meaning of Section 409A and (ii) amounts that would otherwise be payable and benefits
that would otherwise be provided pursuant to this Agreement during the Applicable Period (as defined below) shall instead be paid
on the first business day after the expiration of the Applicable Period, with interest from the date such amounts would otherwise
have been paid at the short-term applicable federal rate, compounded semi-annually, as determined under Section 1274 of the Internal
Revenue Code of 1986, as amended, for the month in which payment would have been made but for the delay in payment required to
avoid the imposition of an additional rate of tax on Executive under Section 409A. The “Applicable Period” shall be
the period commencing on Executive’s separation from service and ending on the date that is six (6) months following Executive’s
separation from service.

 

    			 

     

    

 

11.2.       Survival.
The provisions of Sections 5, 6.1, 6.2, 6.4, 6.5, 7, 8, 9, 10 and 11 shall indefinitely survive Executive’s employment with
the Corporation. The provisions of Section 6.3 shall survive for the Restricted Period, as defined therein.

 

11.3.       Injunctive
Relief. Executive agrees that any breach or threatened breach by him of Sections 6, 7 or 8 of this Agreement shall entitle
the Corporation, in addition to all other legal remedies available to it, to apply to any court of competent jurisdiction to enjoin
such breach or threatened breach without proving actual damage or posting a bond or other security. The parties understand and
intend that each restriction agreed to by Executive herein shall be construed as separable and divisible from every other restriction,
that the unenforceability of any restriction shall not limit the enforceability, in whole or in part, of any other restriction,
and that one or more or all of such restrictions may be enforced in whole or in part as the circumstances warrant. In the event
that any restriction in this Agreement is more restrictive than permitted by law in the jurisdiction in which the Corporation seeks
enforcement thereof, such restriction shall be limited to the extent permitted by law.

 

11.4.       Entire
Agreement. This Agreement constitutes and embodies the entire and complete understanding and agreement of the parties with
respect to Executive’s employment by the Corporation, supersedes all prior understandings and agreements, if any, whether
oral or written, between Executive and the Corporation, including, without limitation, the Prior Agreement, and shall not be amended,
modified or changed except by an instrument in writing executed by the party to be charged. The invalidity or partial invalidity
of one or more provisions of this Agreement shall not invalidate any other provision of this Agreement. No waiver by either party
of any provision or condition to be performed shall be deemed a waiver of similar or dissimilar provisions or conditions at the
same or any prior or subsequent time.

11.5.       Assignment;
Binding Effect. Executive may not assign or delegate any of his or duties under this Agreement. This Agreement shall inure
to the benefit of, be binding upon and enforceable against, the parties hereto and their respective successors and permitted assigns.

11.6.       Captions.
The captions contained in this Agreement are for convenience of reference only and shall not affect in any way the meaning or interpretation
of this Agreement.

 

11.7.       Notices.
All notices, requests, demands and other communications required or permitted to be given hereunder shall be in writing and shall
be deemed to have been duly given when personally delivered or sent by fax or certified, mail, postage prepaid, to the party at
the address set forth above or to such other address as either party may hereafter give notice of in accordance with the provisions
hereof.

 

    			 

     

    

11.8.       Governing
Law. This Agreement shall be governed by and interpreted under the laws of the State of California applicable to contracts
made and to be performed therein without giving effect to the principles of conflict of laws thereof. Except in respect of any
action commenced by a third party in another jurisdiction, the parties hereto agree that any legal suit, action, or proceeding
against them arising out of or relating to this Agreement may be brought in the United States Federal Courts in the State of California
or the state courts, in the State of California. By its execution hereof, the parties hereby irrevocably waive any objection and
any right of immunity on the ground of venue, the convenience of the forum or the jurisdiction of such courts or from the execution
of judgments resulting therefrom. The parties hereby irrevocably accept and submit to the jurisdiction of the aforesaid courts
in any such suit, action or proceeding.

 

11.9.       Waiver
of Jury Trial. THE PARTIES HEREBY WAIVE ANY RIGHT TO TRIAL BY JURY IN ANY ACTION OR PROCEEDING ARISING OUT OF OR RELATING TO
THIS AGREEMENT OR ANY TRANSACTION CONTEMPLATED HEREBY, WHETHER NOW EXISTING OR HEREAFTER ARISING, AND WHETHER SOUNDING IN CONTRACT,
TORT OR OTHERWISE. THE PARTIES AGREE THAT ANY OF THEM MAY FILE A COPY OF THIS PARAGRAPH WITH ANY COURT AS WRITTEN EVIDENCE OF THE
KNOWING, VOLUNTARY AND BARGAINED-FOR AGREEMENT AMONG THE PARTIES IRREVOCABLY TO WAIVE TRIAL BY JURY AND THAT ANY ACTION OR PROCEEDING
WHATSOEVER BETWEEN THEM RELATING TO THIS AGREEMENT OR ANY TRANSACTION CONTEMPLATED HEREBY SHALL INSTEAD BE TRIED IN A COURT OF
COMPETENT JURISDICTION BY A JUDGE SITTING WITHOUT A JURY.

 

11.10.       Counterparts.
This Agreement may be executed and delivered in counterparts, including by facsimile transmission or portable document format (“.pdf”),
each of which shall be deemed an original, but all of which together shall constitute one and the same instrument.

 

    			 

     

    

 

IN WITNESS WHEREOF, the parties hereto
have executed this Agreement as of the date set forth above.

 

	 	 	Humanigen, Inc.
	 	 	 
	 	 	 
	 	 	 	 
	 	 	By:	/s/ Cameron Durrant
	 	 	 	Cameron Durrant, President and CEO
	 	 	 	Date:  August 22, 2018
	 	 	 	 
	 	 	 	 
	 	 	 	 
	 	 	Executive      
	 	 	 	 
	 	 	 	 
	 	 	By:	/s/ Jon G. Jester
	 	 	 	Jon G. Jester
	 	 	 	Date:  August 22, 2018

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