Document:

rptx-ex101_111.htm

 

Exhibit 10.1

SECOND AMENDMENT

TO

COLLABORATION AND LICENSE AGREEMENT

This Second Amendment to Collaboration and License Agreement (this “Second Amendment”) is entered into as of September 24, 2020 (the “Second Amendment Effective Date”) by and between Repare Therapeutics Inc., a Canadian corporation with offices at 7210 Frederick- Banting, Suite 100, St. Laurent, Quebec, Canada H4S 2A1 (“Repare Inc.”) and Repare Therapeutics USA, Inc., a Delaware corporation with offices at One Broadway, 15th Floor, Cambridge, Massachusetts 02142 (“Repare USA” and, together with Repare Inc., “Repare”), on the one hand, and Bristol-Myers Squibb Company, a Delaware corporation with offices at 430 E. 29th Street, 14th Floor, New York, New York 10016 (“BMS”), on the other hand. BMS and Repare are each referred to herein by name or as a “Party”, or, collectively, as the “Parties.” 

WHEREAS, Repare and BMS entered into that certain Collaboration and License Agreement as of May 26, 2020 (as amended, the “Agreement”), pursuant to which, among other things, certain information and data is provided to the BMS members of the JSC on an unblinded basis; and 

WHEREAS, the Parties wish to amend the Agreement to enable unblinding of BMS’s Alliance Manager in the same conditions and subject to the same terms as the unblinding of the BMS JSC members;

NOW, THEREFORE, the Parties, intending to be legally bound, hereby agree as follows: 

	
 
	
1.
	
Capitalized terms used in this Second Amendment that are not defined herein shall have the meanings ascribed to them in the Agreement.

	
 
	
2.
	
Solely for purposes of Sections 2.3, 2.5.1(d); 2.5.2(b), 2.5.5(a), 2.6.3, 5.2.2(o), 5.2.7 and any other provisions of the Agreement governing unblinding of Targets to the JSC, the Alliance Manager appointed by BMS (the “BMS Alliance Manager”) shall be deemed to be a full member of the JSC.  Consequently, unblinding of the BMS Alliance Manager will not constitute or be interpreted as unblinding of BMS.

	
 
	
3.
	
This Second Amendment shall be deemed incorporated into and made a part of the Agreement.  The provisions of this Second Amendment shall constitute an amendment to the Agreement, and, to the extent that any term or provision of this Second Amendment may be deemed expressly inconsistent with any term or provision in the Agreement, this Second Amendment shall govern and control.  Except as expressly modified by the terms of this Second Amendment, all of the terms, conditions, and provisions of the Agreement are hereby ratified, and the Agreement remains in full force and effect.

	
 
	
4.
	
This Second Amendment may be executed in two (2) counterparts, each of which shall be deemed an original, and both of which together shall constitute one and the same instrument.  Any such counterpart, to the extent delivered by means of electronic delivery, shall be treated in all manner and respects as an original executed counterpart and shall be considered to have the same binding legal effect as if it were the original signed version thereof delivered in person.  No Party hereto shall raise the use of electronic delivery to deliver a signature or the fact that any signature or agreement or instrument was transmitted or communicated through the use of electronic delivery as a claim or defense with respect to the formation of a contract, and each Party forever waives any such claim or defense, except to the extent that such claim or defense relates to lack of authenticity.

[Signature Page Follows]

 

DB1/ 116293254.2

 
 

 

IN WITNESS WHEREOF, and intending to be legally bound hereby, the Parties have caused this Second Amendment to Collaboration and License Agreement to be executed by their respective duly authorized officers as of the Second Amendment Effective Date.

 

	
 
	
BRISTOL-MYERS SQUIBB COMPANY

	
 
	
By:
	
 Janeen Doyle

	
 
	
 
	
Name: /s/ Janeen Doyle

	
 
	
 
	
Title: Vice President, Research & Early Development Alliances, Strategy & Business Development

	
 
	
 
	
 

	
 
	
 
	
 

	
 
	
REPARE THERAPEUTICS INC.

	
 
	
By:
	
 Steve Forte

	
 
	
 
	
Name: /s/ Steve Forte

	
 
	
 
	
Title: EVP & CEO

	
 
	
 
	
 

	
 
	
 
	
 

	
 
	
REPARE THERAPEUTICS USA, INC.

	
 
	
By:
	
 Kim A. Seth

	
 
	
 
	
Name: /s/ Kim A. Seth

	
 
	
 
	
Title: EVP, Head of Business and Corporate Development

 

DB1/ 116293254.2rptx-ex102_209.htm

DocuSign Envelope ID: 7319D241-5AE6-4EFA-AAE4-D54C52D2572A

Exhibit 10.2

LEASE AMENDMENT AGREEMENT dated June 11th, 2020.

	
BY AND BETWEEN : 
	
NEOMED INSTITUTE, a corporation governed by the Canada Not-for-profit Corporations Act, having its principal place of business at 7171, Frederick-Banting Street, Saint-Laurent, Province of Québec, H4S 1Z9;

(the “Lessor”)

	
AND: 
	
REPARE THERAPEUTICS INC., a corporation duly incorporated under the Canada Business Corporations Act, with its head office at 7210 Frederick-Banting Street, Suite 100, Saint-Laurent, Province of Québec H4S 2A1 herein acting and represented by Lloyd Segal, Chief Executive Officer, duly authorized for the purposes hereof;

(the “Lessee”)

WHEREAS the Lessor and the Lessee entered into a lease agreement dated as of November 26, 2019 (the "Lease") in respect of the premises in the building being erected at 7171 Frederick-Banting Street, Saint-Laurent, Québec, H4S 1Z9  (the “Building”).

WHEREAS the parties wish to amend the Lease as set forth herein;

NOW, THEREFORE, THE PARTIES AGREE AS FOLLOWS:

	
1.
	
Defined Terms

Capitalized terms used but not defined herein shall have the meaning ascribed thereto in the Offer.

	
2.
	
Additional Leased Premises

	
 
	
2.1
	
The Lessor hereby agrees to lease to the Lessee, hereby accepting, the additional office premises located on the second floor of the Building measuring approximately 1548 square feet and described in Schedule A and referred to as units # 270, 270A, 270B, 270C and 270D and 271 (the “Additional Leased Premises”);

	
 
	
2.2
	
The commencement date for the Additional Leased Premises shall be December 1st, 2020 and the expiry date for the term of the lease thereof shall be the expiry of the Initial Term..

	
 
	
2.3
	
The rent for the Additional Leased Premises shall be at the annual rate of $57,89 per square foot with an annual increase of 2% every lease year starting December 1st, 2021 for the remainder of the Initial Term. Said rent shall be payable in accordance with the terms of the Lease;

	
 
	
2.4
	
All of the terms of the Lease shall apply to the leasing of the Additional Leased Premises mutatis mutandis unless otherwise herein provided, including without limitation Sections

3.2, 3.3 and 3.4 but excluding Section 6.1 of the Lease;

Mtl#: 3022758.2

DocuSign Envelope ID: 7319D241-5AE6-4EFA-AAE4-D54C52D2572A

 

3.Leased Premises

The term “Leased Premises” of the Lease shall be modified to refer also to the Additional Leased Premises, unless herein provided otherwise.

4.Continuing Obligations

Save and except as expressly modified herein, the terms and conditions of the Lease remain unchanged and in full force and effect.

5.Governing Laws

This agreement shall be governed by the laws of the Province of Québec.

6.Counterparts

This Agreement may be executed in any number of counterparts by any one or more of the parties to be bound hereby.  Each executed counterpart shall be deemed to be an original and such counterparts shall together constitute one and the same agreement.

7.Language

The parties acknowledge that they have requested that this Agreement and all documents, notices, correspondence and legal proceedings arising from this Agreement or relating hereto be drawn up in English.  Les parties reconnaissent qu’elles ont exigé que cette convention ainsi que tout document, avis, correspondance et procédure légale découlant de cette convention soient rédigés en anglais.

	
NEOMED INSTITUTE
	
REPARE THERAPEUTICS INC.

	
 
	

	
 
	

	
Per:
	
 
	
 
	
Per:
	
 

	
 
	
Matthew Carlyle, CFO
	
 
	
Lloyd Segal, CEO

 

- 2 -

Mtl#: 3022758.2

DocuSign Envelope ID: 7319D241-5AE6-4EFA-AAE4-D54C52D2572A

 

SCHEDULE A

Plan of Additional Leased Premises

- 3 -

Mtl#: 3022758.2Document

Exhibit 10.1

THE MDU RESOURCES GROUP, INC. DEFERRED COMPENSATION PLAN

ADOPTION AGREEMENT

THIS AGREEMENT is the adoption by MDU Resources Group, Inc. (the "Company") of the MDU Resources Group, Inc. Deferred Compensation Plan ("Plan").

W I T N E S S E T H:

WHEREAS, the Company desires to adopt the Plan as an unfunded, nonqualified deferred compensation plan; and

WHEREAS, the provisions of the Plan are intended to comply with the requirements of Section 409A of the Code and the regulations thereunder and shall apply to amounts subject to section 409A; and

WHEREAS, the Company has been advised by Principal Life Insurance Company to obtain legal and tax advice from its professional advisors before adopting the Plan,

NOW, THEREFORE, the Company hereby adopts the Plan in accordance with the terms and conditions set forth in this Adoption Agreement:

ARTICLE I

Terms used in this Adoption Agreement shall have the same meaning as in the Plan, unless some other meaning is expressly herein set forth. The Company hereby represents and warrants that the Plan has been adopted by the Company upon proper authorization and the Company hereby elects to adopt the Plan for the benefit of its Participants as referred to in the Plan. By the execution of this Adoption Agreement, the Company, for itself and its subsidiaries, hereby agrees to be bound by the terms of the Plan.

ARTICLE II

The Employer hereby makes the following designations or elections for the purpose of the Plan:

2.6    Committee:  The duties of the Committee set forth in the Plan shall be satisfied by:

__    (a)    Company

__    (b)    The administrative committee appointed by the Board to serve at the pleasure of the Board.

__    (c)    Board.

XX    (d)    Other (specify):  The Compensation Committee of the MDU Resources Board of Directors, or its designee.

2.8    Compensation:  The "Compensation" of a Participant shall mean all of a Participant's:

XX    (a)    Base salary.

XX    (b)    Service Bonus.

XX   Service Bonus earned from 1/1 – 12/31, paid on or around first quarter of the following Plan Year.          

__     Service Bonus earned each calendar quarter, paid on or around the following calendar quarter.

__     Service Bonus with no defined earnings period (e.g.: a “spot bonus”)

XX    (c)    Performance-Based Compensation earned in a period of 12 months or more.

XX   Performance Based Bonus earned from 1/1 – 12/31, paid on or around first quarter the following Plan Year and whose elections must be made no later than 6/30 of the Plan Year it is earned.  

__     Performance Based Bonus earned from _______, paid on or around _________ the following Plan Year and whose elections must be made no later than _____ of the Plan Year it is earned. 

__    (d)    Commissions.

XX    (e)    Compensation received as an Independent Contractor reportable on Form 1099.

__    (f)    Other:

2.9    Crediting Date:   The Deferred Compensation Account of a Participant shall be credited as follows:

Participant Deferral Credits at the time designated below:

XX    (a)    On any business day as specified by the Employer.

__    (b)    Each pay day as reported by the Employer.

__    (c)    The last business day of each payroll period during the Plan Year.

Employer Credits at the time designated below:

XX    (a)    On any business day as specified by the Employer.

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2.13    Effective Date:    

XX    (a)    This is a newly-established Plan, and the Effective Date of the Plan is January 1, 2021.

__    (b)    This is an amendment of a plan named _____________________ dated _____________ and governing all contributions to the plan through ________________.  The Effective Date of this amended Plan is ___________.

2.20    Normal Retirement Age: The Normal Retirement Age of a Participant shall be:

__    (a)     Age 65.

__    (b)    The later of age ___ or the _______ anniversary of the participation commencement date. The participation commencement date is the first day of the first Plan Year in which the Participant commenced participation in the Plan.

__    (c)    Other: _____________________________________.

2.23    Participating Employer(s): As of the Effective Date, the following Participating Employer(s) are parties to the Plan:
									
	Name of Employer		EIN
	MDU Resources Group, Inc. for itself and its subsidiaries		30-1133956

2.26    Plan: The name of the Plan is

MDU Resources Group, Inc. Deferred Compensation Plan.

2.28    Plan Year: The Plan Year shall end each year on the last day of the month of December.

2.30    Seniority Date: The date on which a Participant has:

__    (a)    Attained age __. 

__    (b)    Completed __ Years of Service from First Date of Service.

__    (c)    Attained age __and completed __Years of Service from First Date of Service.

XX    (d)    Not applicable – distribution elections for Separation from Service are not based on Seniority Date.

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4.1    Participant Deferral Credits: Subject to the limitations in Section 4.1 of the Plan, a Participant may elect to have his Compensation (as selected in Section 2.8 of this Adoption Agreement) deferred within the annual limits below by the following percentage or amount as designated in writing to the Committee:

XX    (a)    Base salary:
									
	minimum deferral:		%
	maximum deferral:	80	%

XX    (b)    Service Bonus:

XX    Service Bonus        
									
	minimum deferral:		%
	maximum deferral:	100	%

XX    (c)    Performance-Based Compensation:

XX    Performance Based Bonus 
									
	minimum deferral:		%
	maximum deferral:	100	%

__    (d)    Commissions:
									
	minimum deferral:		%
	maximum deferral:		%

XX    (e)    Form 1099 Compensation:
									
	minimum deferral:		%
	maximum deferral:	100	%

__    (f)    Other: 
									
	minimum deferral:		%
	maximum deferral:		%

__    (g)    Participant deferrals not allowed.

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4.1.2    Participant Deferral Credits and Employer Credits – Election Period:  Participant elections regarding Participant Deferral Credits and Employer Credits shall be subject to the following effective periods (one must be selected):

XX     (a)    Evergreen election.  An election made by the Participant shall continue in effect for subsequent years until modified by the Participant as permitted in Section 4.1 and Section 4.2. (This option is not permitted if source year accounts are elected in Section 4.3)

__    (b)    Non-Evergreen election.  Any election made by the Participant shall only remain in effect for the current election period and will then expire. An election for each subsequent year will be required as permitted in Sections 4.1 and 4.2.

4.2    Employer Credits: Employer Credits will be made in the following manner:

XX    (a)    Employer Credits 1 (Employer Discretionary Credits): The Employer may make discretionary credits to the Deferred Compensation Account of each Active Participant in an amount determined as follows:

XX    (i)    An amount determined each Plan Year by the Employer.

__    (ii)    Other: _______________________________________.

__    (b)    Employer Credits 2 (Other Employer Credits): The Employer may make other credits to the Deferred Compensation Account of each Active Participant in an amount determined as follows:

__    (i)    An amount determined each Plan Year by the Employer.

__    (ii)    Other: _______________________________________.

__    (c)    Employer Credits not allowed.

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4.3    Deferred Compensation Account:  The Participant is permitted to establish the following accounts:

XX    (a)    Non-source year account(s).  Deferred Compensation Account(s) will not be established on a source year basis:

__    (i)    A Participant may establish only one account to be distributed upon Separation from Service. One set of payment options for that account is allowed as permitted in Section 7.1. Additional In-Service or Education accounts may be established as permitted in Section 5.4.

XX    (ii)    A Participant may establish multiple accounts to be distributed upon Separation from Service.  Each account may have one set of payment options as permitted in Section 7.1 Additional In-Service or Education accounts may be established as permitted in Section 5.4. If this multiple account option is elected, the Participant will also be required to elect Separation from Service payment options for each In-Service or Education account established.

__    (b)    Source year account(s):  Annual Deferred Compensation Account(s) will be established each year in which Participant Deferral Credits or Employer Credits are credited to the Participant. Only one account may be established each year for distribution upon Separation from Service. One set of payment options for that account is allowed as permitted in Section 7.1. Additional In-Service or Education accounts may be established for each source year as permitted in Section 5.4. If this option is selected, Evergreen elections as described in Section 4.1.2 are not permitted.

5.2    Disability of a Participant: 

XX    (a)    A Participant's becoming Disabled shall be a Qualifying Distribution Event and the Deferred Compensation Account shall be paid by the Employer as provided in Section 7.1.

__    (b)    A Participant becoming Disabled shall not be a Qualifying Distribution Event.

5.3    Death of a Participant: If the Participant dies while in Service, the Employer shall pay a benefit to the Beneficiary in an amount equal to the vested balance in the Deferred Compensation Account of the Participant determined as of the date payments to the Beneficiary commence, plus:

__    (a)    An amount to be determined by the Committee.

XX    (b)    No additional benefits.

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5.4    In-Service or Education Distributions: In-Service and Education Accounts are permitted under the Plan:

XX    (a)    In-Service Accounts are allowed with respect to:
XX    Participant Deferral Credits only.
__    Employer Credits only.
__    Participant Deferral and Employer Credits.

In-service distributions may be made in the following manner:
XX    Single lump sum payment.
XX    Annual installments over a term certain not to exceed 5 years.

Education Accounts are allowed with respect to:
__    Participant Deferral Credits only.
__    Employer Credits only.
__    Participant Deferral and Employer Credits.

Education Accounts distributions may be made in the following manner:
__    Single lump sum payment.
__    Annual installments over a term certain not to exceed __ years.

If applicable, amounts not vested at the time payments due under this Section cease will be:
__    Forfeited
__    Distributed at Separation from Service if vested at that time

__    (b)    No In-Service or Education Distributions permitted.

5.5    Change in Control Event: 

__    (a)    Participants may elect upon initial enrollment to have accounts distributed                                                           upon a Change in Control Event.

XX    (b)    A Change in Control shall not be a Qualifying Distribution Event.

5.6    Unforeseeable Emergency Event: 

XX    (a)    Participants may apply to have accounts distributed upon an Unforeseeable Emergency event.

__     (b)    An Unforeseeable Emergency shall not be a Qualifying Distribution Event.

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6.    Vesting:  An Active Participant shall be vested in the Employer Credits made to the Deferred Compensation Account upon the first to occur of the following events:

___    (a)    Normal Retirement Age.

XX    (b)    Full vesting upon Death.

XX    (c)    Full vesting upon Disability.

XX    (d)    Full vesting upon separation from service with the Company (within the meaning of Code Section 409A) after attaining age sixty-five (65) and completing at least ten (10) “years of continuous service” with the Company.

XX    (e)    Involuntary separates from service with the Company within twelve (12) months of a “change in control” of the Participant’s  direct Employer (within the meaning of Code Section 409A), then such Participant shall have a nonforfeitable (vested) right to 100% of the amounts credited to the Participant’s account(s).  

XX    (f)    Satisfaction of the vesting requirement as specified below:

__    (i)    Immediate 100% vesting.

__    (ii)    100% vesting after __ Years of Service.

__    (iii)    100% vesting at age __.

XX    (iv)
												
	Number of Years of Service		Vested Percentage
	Less than	1	0	%
		1	34	%
		2	67	%
		3	100	%
		4		%
		5		%
		6		%
		7		%
		8		%
		9		%
		10 or more		%

For this purpose, Years of Service of a Participant shall be calculated from the date designated below:

__    (1)    First day of Service.

__    (2)    Effective date of Plan participation.

XX    (3)    Each Crediting Date. Under this option (3), each Employer Credit shall vest based on the Years of Service of a Participant from the Crediting Date on which each Employer Credit is made to his or her Deferred Compensation Account.
8

__    Employer Credits 2 (Other Employer Credits):

__    (i)    Immediate 100% vesting.

__    (ii)    100% vesting after __ Years of Service.

__    (iii)    100% vesting at age __.

__    (iv)    
												
	Number of Years of Service		Vested Precentage
	Less than	1		%
		1		%
		2		%
		3		%
		4		%
		5		%
		6		%

For this purpose, Years of Service of a Participant shall be calculated from the date designated below:

__    (1)    First day of Service.

__    (2)    Effective date of Plan participation.

__    (3)    Each Crediting Date. Under this option (3), each Employer Credit shall vest based on the Years of Service of a Participant from the Crediting Date on which each Employer Discretionary Credit is made to his or her Deferred Compensation Account.

7.1    Payment Options: Any benefit payable under the Plan upon a permitted Qualifying Distribution Event may be made to the Participant or his Beneficiary (as applicable) in any of the following payment forms, as selected by the Participant in the Participation Agreement: 

(a)    Separation from Service (Seniority Date is Not Applicable)

XX    (i)    A lump sum.

XX    (ii)    Annual installments over a term certain as elected by the Participant not to exceed 10 years.

(b)    Separation from Service prior to Seniority Date (If Applicable)

__    (i)    A lump sum.

XX    (ii)    Not Applicable

(c)    Separation from Service on or After Seniority Date (If Applicable)

__    (i)    A lump sum.
9

__    (ii)    Annual installments over a term certain as elected by the Participant not to exceed __years.

XX    (iii)    Not Applicable

(d)    Separation from Service Upon a Change in Control Event

XX    (i)    A lump sum.

(e)    Death

XX    (i)    A lump sum.

__    (ii)    Annual installments over a term certain as elected by the Participant not to exceed __ years.

(f)    Disability

XX    (i)    A lump sum.

XX    (ii)    Annual installments over a term certain as elected by the Participant not to exceed 10 years.

__    (iii)    Not applicable.

If applicable, amounts not vested at the time payments due under this Section cease will be:
__    Forfeited
__    Distributed at Separation from Service if vested at that time

(g)    Change in Control Event

__    (i)    A lump sum.

XX    (ii)    Not Applicable

If applicable, amounts not vested at the time payments due under this Section cease will be:
__    Forfeited
__    Distributed at Separation from Service if vested at that time

7.4        De Minimis Amounts. 

XX    (a)    Notwithstanding any payment election made by the Participant, the vested balance in all Deferred Compensation Account(s) of the Participant will be distributed in a single lump sum payment at the time designated under the Plan if at the time of a permitted Qualifying Distribution Event that is either a Separation from Service, death, Disability (if applicable) or Change in Control Event (if applicable) the vested balance does not exceed $50,000.  In addition, the Employer may distribute a Participant's vested balance in all Deferred Compensation Account(s) of the Participant at any time if the balance does not exceed the limit in Section 402(g)(1)(B) of the Code and results in the termination of the Participant's entire interest in the Plan 
10

and any other Employer plan subject to aggregation under Section 409A of the Code.

__    (b)    There shall be no pre-determined de minimis amount under the Plan; however, the Employer may distribute a Participant's vested balance at any time if the balance does not exceed the limit in Section 402(g)(1)(B) of the Code and results in the termination of the Participant's entire interest in the Plan and any other Employer plan subject to aggregation under Section 409A of the Code.

10.1    Contractual Liability: Liability for payments under the Plan shall be the responsibility of the:

XX    (a)    Company.

__    (b)    Employer or Participating Employer who employed the Participant when amounts were deferred.

14.    Amendment and Termination of Plan: Notwithstanding any provision in this Adoption Agreement or the Plan to the contrary, Section ______ of the Plan shall be amended to read as provided in attached Exhibit _____________

XX    There are no amendments to the Plan.

17.8    Construction: The provisions of the Plan shall be construed and enforced according to the laws of the State of North Dakota, except to the extent that such laws are superseded by ERISA and the applicable provisions of the Code.

IN WITNESS WHEREOF, this Agreement has been executed as of the day and year stated below.

									
		MDU Resources Group, Inc.
		Name of Employer
		
		By:	/s/ Anne M. Jones, Vice President, Human Resources
		Authorized Person
		Date:	11-12-20
			

11

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