Document:

Exhibit 4.1 

 

EXHIBIT A

 

SUBSCRIPTION AGREEMENT

 

AVALON GLOBOCARE CORP. 

 

Avalon GloboCare Corp.
(the “Company”) has authorized for sale 4,000,000 shares of Common Stock (“Common Stock”) on a “best
efforts” basis for the maximum offering of $4,000,000. The undersigned hereby subscribes for the Shares for the Subscription
Price (as defined below and on the signature page attached hereto). The shares of Common Stock offered for sale by the Company
are hereinafter referred to as the Shares shall also be referred to as the “Securities”. There is no escrow in this
offering. The Company will be entitled to use the proceeds individually upon receipt from the subscriber.

 

The undersigned agrees
to pay the Subscription Price for the Securities being purchased hereunder. The entire purchase price is due and payable upon the
submission of this Subscription Agreement and shall be payable by wire transfer or check. However, in such event that the Subscription
Price has been previously paid, then the Subscription Price shall be deemed fully paid.

 

The Company has the right
to reject this subscription in whole or in part.

 

The undersigned acknowledges
that the Securities being purchased hereunder and its component securities will not be registered under the Securities Act of 1933
(the “Act”), or the securities laws of any state (the “State Acts”), in reliance upon an exemption from the
registration requirements of the Act and the State Acts; that absent an exemption from registration contained in the Act and the
State Acts, the Securities, would require registration; and that the Company’s reliance upon such exemptions is based, in material
part, upon the undersigned’s representations, warranties, and agreements contained in this Subscription Agreement.

 

1.             The
undersigned represents, warrants, and agrees as follows:

 

a.           The
undersigned agrees that this Subscription Agreement is and shall be irrevocable.

 

b.           The
undersigned has carefully read the Confidential Private Offering Memorandum, dated September 25, 2017, and exhibits thereto (the
“Memorandum”) and the risk factors contained therein. The undersigned has been given the opportunity to ask questions
of, and receive answers from, the Company concerning the terms and conditions of this Offering and the Memorandum and to obtain
such additional information, to the extent the Company possesses such information or can acquire it without unreasonable effort
or expense, necessary to verify the accuracy of same as the undersigned reasonably desires in order to evaluate the investment.
The undersigned understands the Memorandum and the undersigned has had the opportunity to discuss any questions regarding any of
the disclosure in the Memorandum with his counsel or other advisor. Notwithstanding the foregoing, the only information upon which
the undersigned has relied is that set forth in the Memorandum and the associated risk factors. The undersigned has received no
representations or warranties from the Company, its employees, agents or attorneys, in making this investment decision other than
as set forth in the Memorandum. The undersigned does not desire to receive any further information.

 

     

     

    

 

c.           The
undersigned is aware that the purchase of the Securities is a speculative investment involving a high degree of risk, that there
is no guarantee that the undersigned will realize any gain from this investment, and that the undersigned could lose the total
amount of this investment.

 

d.           The
undersigned understands that no federal or state agency has made any finding or determination regarding the fairness of the Securities
for investment, or any recommendation or endorsement of the Share.

 

e.           The
undersigned is purchasing the Securities for the undersigned’s own account, with the intention of holding the Securities with no
present intention of dividing or allowing others to participate in this investment or of reselling or otherwise participating,
directly or indirectly, in a distribution of the Securities, and shall not make any sale, transfer, or pledge thereof without registration
under the Act and any applicable securities laws of any state or unless an exemption from registration is available under those
laws.

 

f.           The
undersigned represents that if an individual, he has adequate means of providing for his or her current needs and personal and
family contingencies and has no need for liquidity in this investment in the Securities. The undersigned has no reason to anticipate
any material change in his or her personal financial condition for the foreseeable future.

 

g.           The
undersigned is financially able to bear the economic risk of this investment, including the ability to hold the Securities indefinitely,
or to afford a complete loss of his investment in the Securities.

 

h.           The
undersigned represents that the undersigned’s overall commitment to investments which are not readily marketable is not disproportionate
to the undersigned’s net worth, and the undersigned’s investment in the Securities will not cause such overall commitment to become
excessive. The undersigned understands that the statutory basis on which the Securities are being sold to the undersigned and others
would not be available if the undersigned’s present intention were to hold the Securities for a fixed period or until the occurrence
of a certain event. The undersigned realizes that in the view of the Securities and Exchange Commission (the “Commission”),
a purchase now with a present intent to resell by reason of a foreseeable specific contingency or any anticipated change in the
market value, or in the condition of the Company, or that of the industry in which the business of the Company is engaged or in
connection with a contemplated liquidation, or settlement of any loan obtained by the undersigned for the acquisition of the Securities,
and for which such Securities may be pledged as security or as donations to religious or charitable institutions for the purpose
of securing a deduction on an income tax return, would, in fact, represent a purchase with an intent inconsistent with the undersigned’s
representations to the Company, and the Commission would then regard such sale as a sale for which the exemption from registration
is not available. The undersigned will not pledge, transfer or assign this Subscription Agreement.

 

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i.           The
undersigned represents that the funds provided for this investment are either separate property of the undersigned, community property
over which the undersigned has the right of control, or are otherwise funds as to which the undersigned has the sole right of management.
The undersigned is purchasing the Securities with the funds of the undersigned and not with the funds of any other person, firm,
or entity and is acquiring the Securities for the undersigned’s account. No person other than the undersigned has any beneficial
interest in the Securities being purchased hereunder.

 

j.           The
address shown under the undersigned’s signature at the end of this Subscription Agreement is the undersigned’s principal residence
if he or she is an individual, or its principal business address if it is a corporation or other entity.

 

k.           The
undersigned has such knowledge and experience in financial and business matters as to be capable of evaluating the merits and risks
of an investment in the Securities.

 

l.            The
undersigned acknowledges that the certificates for the Securities which the undersigned will receive will contain a legend substantially
as follows:

 

THE SECURITIES
WHICH ARE REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”).
THE SECURITIES HAVE BEEN ACQUIRED FOR INVESTMENT PURPOSES ONLY AND NOT WITH A VIEW TO DISTRIBUTION OR RESALE, AND MAY NOT BE SOLD,
TRANSFERRED, MADE SUBJECT TO A SECURITY INTEREST, PLEDGED, HYPOTHECATED OR OTHERWISE DISPOSED OF UNLESS AND UNTIL REGISTERED UNDER
THE SECURITIES ACT OF 1933 (THE “ACT”), AS AMENDED, OR EVIDENCE SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATION IS
NOT REQUIRED UNDER SUCH ACT.

 

The undersigned further
acknowledges that a stop transfer order will be placed upon the certificates for the securities in accordance with the Act. The
undersigned further acknowledges that the Company is under no obligation to aid the undersigned in obtaining any exemption from
registration requirements.

 

m.          The undersigned represents that he is an “accredited investor” as that term is defined under the Act.

 

n.           The undersigned represents that (i) the undersigned was contacted regarding the sale of the Securities by the Company (or an authorized
agent or representative thereof) with whom the undersigned had a prior substantial pre-existing relationship and (ii) no Securities
were offered or sold to it by means of any form of general solicitation or general advertising, and in connection therewith, the
undersigned did not (A) receive or review any advertisement, article, notice or other communication published in a newspaper or
magazine or similar media or broadcast over television or radio, whether closed circuit, or generally available; or (B) attend
any seminar meeting or industry investor conference whose attendees were invited by any general solicitation or general advertising.
The undersigned is not aware of nor did it review any registration statement or prospectus filed by the Company with the SEC.

 

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2.             The
undersigned expressly acknowledges and agrees that the Company is relying upon the undersigned’s representations contained in the
Subscription Agreement.

 

3.             The
Company has been duly and validly incorporated and is validly existing and in good standing as a corporation under the laws of
the State of Delaware. The Company represents that it has all requisite power and authority, and all necessary authorizations,
approvals and orders required as of the date hereof to enter into this Subscription Agreement and to be bound by the provisions
and conditions hereof.

 

4.             Except
as otherwise specifically provided for hereunder, no party shall be deemed to have waived any of his or its rights hereunder or
under any other agreement, instrument or papers signed by any of them with respect to the subject matter hereof unless such waiver
is in writing and signed by the party waiving said right. Except as otherwise specifically provided for hereunder, no delay or
omission by any party in exercising any right with respect to the subject matter hereof shall operate as a waiver of such right
or of any such other right. A waiver on any one occasion with respect to the subject matter hereof shall not be construed as a
bar to, or waiver of, any right or remedy on any future occasion. All rights and remedies with respect to the subject matter hereof,
whether evidenced hereby or by any other agreement, instrument, or paper, will be cumulative, and may be exercised separately or
concurrently.

 

5.             The
parties have not made any representations or warranties with respect to the subject matter hereof not set forth herein, and this
Subscription Agreement, together with any instruments or documents executed simultaneously herewith in connection with this offering,
constitutes the entire agreement between them with respect to the subject matter hereof. All understandings and agreements heretofore
had between the parties with respect to the subject matter hereof are merged in this Subscription Agreement and any such instruments
and documents, which alone fully and completely expresses their agreement.

 

6.             This
Subscription Agreement may not be changed, modified, extended, terminated or discharged orally, but only by an agreement in writing,
which is signed by all of the parties to this Subscription Agreement.

 

7.             The
parties agree to execute any and all such other further instruments and documents, and to take any and all such further actions
reasonably required to effectuate this Subscription Agreement and the intent and purposes hereof.

 

8.             This
Subscription Agreement shall be governed by and construed in accordance with the laws of the State of New Jersey and the undersigned
hereby consents to the jurisdiction of the courts of the State of New Jersey and the United States District Courts situated therein.

 

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9.             The
undersigned represents and warrants that he, she or it comes within one category marked below, and that for any category marked,
he, she or it has truthfully set forth, where applicable, the factual basis or reason the undersigned comes within that category.
ALL INFORMATION IN RESPONSE TO THIS SECTION WILL BE KEPT STRICTLY CONFIDENTIAL. The undersigned agrees to furnish any additional
information which the Company deems necessary in order to verify the answers set forth below.

 

		Category A___	The undersigned is an individual (not a partnership,
corporation, etc.) whose individual net worth, or joint net worth with his or her spouse, presently exceeds $1,000,000. (In calculating
net worth you may include equity in personal property and real estate (but excluding your principal residence), cash, short-term
investments, stock and securities. Equity in personal property and real estate should be based on the fair market value of such
property less debt secured by such property.)

 

		Category B___	The undersigned is an individual (not a partnership,
corporation, etc.) who had an income in excess of $200,000 in each of the two most recent years, or joint income with his or her
spouse in excess of $300,000 in each of those years (in each case including foreign income, tax exempt income and full amount
of capital gains and losses but excluding any income of her family members and any unrealized capital appreciation) and has a
reasonable expectation of reaching the same income level in the current year.

 

		Category C___	The undersigned is a director or executive officer of
the Company.

 

		Category D___	The undersigned is a bank; a savings and loan association;
insurance company; registered investment company; registered business development company; licensed small business investment
company (“SBIC”); or employee benefit plan within the meaning of Title 1 of ERISA and (a) the investment decision is
made by a plan fiduciary which is either a bank, savings and loan association, insurance company or registered investment advisor,
or (b) the plan has total assets in excess of $5,000,000 or (c) is a self directed plan with investment decisions made solely
by persons that are accredited investors. (describe entity)

 

		Category E___	The undersigned is a private business development company
as defined in section 202(a)(22) of the Investment Advisors Act of 1940. (describe entity)

 

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		Category F___	The undersigned is either a corporation, partnership,
Massachusetts business trust, or non-profit organization within the meaning of Section 501(c)(3) of the Internal Revenue Code,
in each case not formed for the specific purpose of acquiring the Securities and with total assets in excess of $5,000,000. (describe
entity)

 

		Category G___	The undersigned is a trust with total assets in excess
of $5,000,000, not formed for the specific purpose of acquiring the Securities, where the purchase is directed by a “sophisticated
investor” as defined in Regulation 506(b)(2)(ii) under the Act.

 

		Category H___	The undersigned is an entity (other than a trust) in
which all of the equity owners are “accredited investors” within one or more of the above categories. If relying upon
this Category alone, each equity owner must complete a separate copy of this agreement.

 

The undersigned agrees that the undersigned
will notify the Company at any time on or prior to the closing in the event that the representations and warranties in this agreement
shall cease to be true, accurate and complete.

 

10.           SUITABILITY
(please answer each question)

 

(a)           Please
describe your current employment, including the company by which you are employed and its principal business:

 

(b)           Please
describe any college or graduate degrees held by you:

 

(c)           Please
list types of prior investments:

 

(d)           Please
state whether you have participated in other private placements before:

 

YES_______               NO_______

 

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(e)           If
your answer to question (d) above was “YES”, please indicate frequency of such prior participation in private placements
of:

 

	 	Public Companies	Private Companies
	Frequently	 	 
	Occasionally	 	 
	Never	 	 

 

(f)            Do
you expect your current level of income to significantly decrease in the foreseeable future:

 

YES_______               NO_______

 

(g)           For
trust, corporate, partnership and other institutional subscribers, do you expect your total assets to significantly decrease in
the foreseeable future:

 

YES_______               NO_______

 

(h)           Do
you have any other investments or contingent liabilities which you reasonably anticipate could cause you to need sudden cash requirements
in excess of cash readily available to you:

 

YES_______               NO_______

 

(i)            Are
you familiar with the risk aspects and the non-liquidity of investments such as the securities for which you seek to subscribe?

 

YES_______               NO_______

 

(j)            Do
you understand that there is no guarantee of financial return on this investment and that you run the risk of losing your entire
investment?

 

YES_______               NO_______

 

11.           MANNER
IN WHICH TITLE IS TO BE HELD. (circle one)

 

(a)        Individual
Ownership

(b)       Community
Property

(c)        Joint
Tenant with Right of Survivorship (both parties must sign)

(d)       Partnership

(e)       Tenants
in Common

(f)        Company

(g)       Trust

(h)       Other

 

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12.           FINRA
AFFILIATION.

 

Are you affiliated or associated with an
FINRA member firm (please check one):

 

Yes _________           No __________

 

If Yes, please describe:

 

If you are affiliated or associated with
an FINRA member firm, please advise if you are purchasing the Securities in the ordinary course of business and that you have no
agreements or understandings, directly or indirectly, with any person to distribute the securities. (please check one):

 

Yes _________           No __________

 

*If the undersigned is a Registered Representative
with an FINRA member firm, have the following acknowledgment signed by the appropriate party:

 

The undersigned FINRA member firm acknowledges
receipt of the notice required by Article 3, Sections 28(a) and (b) of the Rules of Fair Practice.

 

	 	 
	Name of FINRA Member Firm
	 	 	 
	 	 	 
	By:	 	 
	 	    Authorized Officer

 

Date:

 

13.          The
undersigned is informed of the significance to the Company of the foregoing representations and answers contained therein and such
answers have been provided under the assumption that the Company will rely on them.

 

[REMAINDER OF PAGE INTENTIONALLY LEFT
BLANK]

 

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EXECUTION BY SUBSCRIBER

 

$_________________________ ($1.00 per share)
(the “Subscription Price”)

 

Shares_____________________ (determined
by dividing the above subscription amount by $1.00)

 

	 
	Exact Name in Which Title is to be Held
	 	 	 
	 
	(Signature)
	 	 	 
	 
	Name and Title (if applicable)
	 	 	 
	 
	Address: Number and Street
	 	 	 
	 	 	 
	City	State	Zip Code
	 	 	 
	 
	Social Security Number or Tax Identification Number

 

Accepted this ___ day of _________, 2017
on behalf of Avalon GloboCare Corp.

 

	 	By:	 
	 	Name:
	 	Title:

 

    8Exhibit 10.1

 

SECURITIES PURCHASE AGREEMENT

 

This SECURITIES
PURCHASE AGREEMENT (the “Agreement”), dated as of October 25, 2017, by and between GenExosome Technologies
Inc., a Nevada corporation (the “Company”), and Avalon GloboCare Corp., a Delaware corporation (“Investor”).

 

WHEREAS:

 

A.            The
Company and Investor are executing and delivering this Agreement in reliance upon the exemption from securities registration afforded
by the rules and regulations as promulgated by the United States Securities and Exchange Commission (the “SEC”)
under the Securities Act of 1933, as amended (the “1933 Act”);

 

B.            Investor
desires to purchase and the Company desires to issue and sell, upon the terms and conditions set forth in this Agreement, 600
shares of common stock, $0.0001 par value (the “Common Stock”) of the Company (the “Shares”
or the “Securities”).

 

C.            Closing. 
The purchase and sale of the Shares shall take place at one closing (the “Closing”).  The Closing of the
transaction contemplated by this Agreement shall take place on the date hereof simultaneously with the execution and delivery of
this Agreement by all parties hereto (such date, the “Closing Date”).  Subject to the terms and conditions
hereof, at the Closing, Investor shall subscribe for and purchase the Shares from the Company in consideration of (i) $1,326,087
(the “Cash Purchase Price”) and (ii) 500,000 shares of common stock of the Investor (the the “Equity
Purchase Price” and together with the Cash Purchase Price, the “Purchase Price”), and the Company
shall issue and sell such Shares to Investor for the Purchase Price.

 

NOW THEREFORE,
the Company and Investor severally (and not jointly) hereby agree as follows:

 

1.            Purchase
and Sale of the Shares.

 

a.            Purchase
of the Shares. On the Closing Date, the Company shall issue and sell to Investor and Investor agrees to purchase from the Company
the Shares for the Purchase Price. Within thirty (30) days, Investor shall pay $876,087 of the Cash Purchase Price by wire transfer
of immediately available funds to the Company, in accordance with the Company’s written wiring instructions. Within sixty
(60) days, Investor shall pay $450,000 of the Cash Purchase Price by wire transfer of immediately available funds to the Company,
in accordance with the Company’s written wiring instructions. In addition, Investor shall direct its transfer agent to issue
and deliver the Equity Purchase Price within thirty (30) days of the Closing. 

 

b.            Closing
Date. Investor agrees to pay the Purchase Price for the Shares being purchased hereunder. The Cash Purchase Price is due and
payable upon the execution and delivery of this Agreement on the Closing Date and shall be payable by wire transfer and the Equity
Purchase Price shall be delivered as set forth above. 

 

c.            Closing
Deliveries.

 

(i)            At
the Closing, the Company shall deliver to Investor a certificate evidencing the Shares being purchased at the Closing.  

 

(ii)           At
the Closing, Investor shall deliver and pay to the Company, by wire transfer of immediately available funds to the account specified
in advance by the Company, the Cash Purchase Price.

 

(iii)          Investor
shall direct its transfer agent to issue and deliver the Equity Purchase Price within thirty (30) days of the Closing.

 

    

     

    

 

(iv)         The issuance of
the above Securities will be exempt from the registration requirements of the Securities Act of 1933, as amended (the “Act”),
pursuant to an exemption provided by Section 4(2) thereunder and/or Regulation D as promulgated under the Act.

 

2.            Investor’s
Representations and Warranties. Investor represents and warrants to the Company that:

 

a.            Investment
Purpose. Investor is purchasing the Shares pursuant to this Agreement for its own account and not with a present view towards
the public sale or distribution thereof, except pursuant to sales registered or exempted from registration under the 1933 Act;
provided, however, that by making the representations herein, Investor does not agree to hold any of the Securities
for any minimum or other specific term and reserves the right to dispose of the Securities at any time in accordance with or pursuant
to a registration statement or an exemption under the 1933 Act.

 

b.            Accredited
Investor Status. Investor is an “accredited investor” as that term is defined in Rule 501(a) of Regulation D (an
“Accredited Investor”).

 

c.            Reliance
on Exemptions. Investor understands that the Securities are being offered and sold to it in reliance upon specific exemptions
from the registration requirements of United States federal and state securities laws and that the Company is relying upon the
truth and accuracy of, and Investor’s compliance with, the representations, warranties, agreements, acknowledgments and understandings
of Investor set forth herein in order to determine the availability of such exemptions and the eligibility of Investor to acquire
the Securities.

 

d.            Information.
Investor and its advisors, if any, have been furnished with all materials relating to the business, finances and operations of
the Company and materials relating to the offer and sale of the Securities which have been requested by Investor or his advisors.
Investor and its advisors, if any, have been, afforded the opportunity to ask questions of the Company. Neither such inquiries
nor any other due diligence investigation conducted by Investor or any of his advisors or representatives shall modify, amend or
affect Investor’s right to rely on the Company’s representations and warranties contained in Section 3 below. Investor
understands that its investment in the Securities involves a significant degree of risk.

 

e.            Governmental
Review. Investor understands that no United States federal or state agency or any other government or governmental agency has
passed upon or made any recommendation or endorsement of the Securities.

 

f.             Transfer
or Re-sale. Investor understands that (i) the sale or re-sale of the Securities has not been and is not being registered under
the 1933 Act or any applicable state securities laws, and the Securities may not be transferred unless (a) the Securities
are sold pursuant to an effective registration statement under the 1933 Act, (b) Investor shall have delivered to the Company,
at the cost of Investor, an opinion of counsel that shall be in form, substance and scope customary for opinions of counsel in
comparable transactions to the effect that the Securities to be sold or transferred may be sold or transferred pursuant to an exemption
from such registration, (c) the Securities are sold or transferred to an “affiliate” (as defined in Rule 144 promulgated
under the 1933 Act (or a successor rule) (“Rule 144”)) of Investor who agrees to sell or otherwise transfer
the Securities only in accordance with this Section 2(f) and who is an Accredited Investor, (d) the Securities are sold pursuant
to Rule 144, or (e) the Securities are sold pursuant to Regulation S under the 1933 Act (or a successor rule) (“Regulation
S”), and Investor shall have delivered to the Company, at the cost of Investor, an opinion of counsel that shall be in
form, substance and scope customary for opinions of counsel in corporate transactions; (ii) any sale of such Securities made in
reliance on Rule 144 may be made only in accordance with the terms of said Rule and further, if said Rule is not applicable, any
re-sale of such Securities under circumstances in which the seller (or the person through whom the sale is made) may be deemed
to be an underwriter (as that term is defined in the 1933 Act) may require compliance with some other exemption under the 1933
Act or the rules and regulations of the SEC thereunder; and (iii) neither the Company nor any other person is under any obligation
to register such Securities under the 1933 Act or any state securities laws or to comply with the terms and conditions of any exemption
thereunder (in each case). Notwithstanding the foregoing or anything else contained herein to the contrary, the Securities may
be pledged as collateral in connection with a bona fide margin account or other lending arrangement. 

 

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g.            Legends.
Investor understands that until such time as the Shares have been registered under the 1933 Act or may be sold pursuant to Rule
144 or Regulation S without any restriction as to the number of securities as of a particular date that can then be immediately
sold, the Shares may bear a restrictive legend in substantially the following form (and a stop-transfer order may be placed against
transfer of the certificates for such Securities):

 

“NEITHER THE ISSUANCE AND SALE
OF THE SECURITIES REPRESENTED BY THIS CERTIFICATE NOR THE SECURITIES INTO WHICH THESE SECURITIES ARE EXERCISABLE HAVE BEEN REGISTERED
UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THE SECURITIES MAY NOT BE OFFERED FOR SALE,
SOLD, TRANSFERRED OR ASSIGNED (I) IN THE ABSENCE OF (A) AN EFFECTIVE REGISTRATION STATEMENT FOR THE SECURITIES UNDER THE SECURITIES
ACT OF 1933, AS AMENDED, OR (B) AN OPINION OF COUNSEL, IN A GENERALLY ACCEPTABLE FORM, THAT REGISTRATION IS NOT REQUIRED UNDER
SAID ACT OR (II) UNLESS SOLD PURSUANT TO RULE 144 OR RULE 144A UNDER SAID ACT.”

 

h.            Authorization;
Enforcement. This Agreement has been duly and validly authorized. This Agreement has been duly executed and delivered on behalf
of Investor, and this Agreement constitutes a valid and binding agreement of Investor enforceable in accordance with its terms.

 

i.             Residency.
Investor is a resident of the jurisdiction set forth immediately below Investor’s name on the signature pages hereto. 

 

3.            Representations
and Warranties of the Company. The Company represents and warrants to Investor that:

 

a.            Organization
and Qualification. The Company and each of its subsidiaries (as defined below), if any, is a corporation duly organized, validly
existing and in good standing under the laws of the jurisdiction in which it is incorporated, with full power and authority (corporate
and other) to own, lease, use and operate its properties and to carry on its business as and where now owned, leased, used, operated
and conducted. The Company and each of its Subsidiaries is duly qualified as a foreign corporation to do business and is in good
standing in every jurisdiction in which its ownership or use of property or the nature of the business conducted by it makes such
qualification necessary except where the failure to be so qualified or in good standing would not have a Material Adverse Effect.
“Material Adverse Effect” means any material adverse effect on the business, operations, assets, financial condition
or prospects of the Company or its Subsidiaries, if any, taken as a whole, or on the transactions contemplated hereby or by the
agreements or instruments to be entered into in connection herewith. “Subsidiaries” means any corporation or other
organization, whether incorporated or unincorporated, in which the Company owns, directly or indirectly, any equity or other ownership
interest.

 

b.            Authorization;
Enforcement. (i) The Company has all requisite corporate power and authority to enter into and perform this Agreement and to
consummate the transactions contemplated hereby and thereby and to issue the Securities, in accordance with the terms hereof and
thereof, (ii) the execution and delivery of this Agreement by the Company and the consummation by it of the transactions contemplated
hereby and thereby (including without limitation, the issuance of the Shares) have been duly authorized by the Company’s
Board of Directors and no further consent or authorization of the Company, its Board of Directors, or its shareholders is required,
(iii) this Agreement has been duly executed and delivered by the Company by its authorized representative, and such authorized
representative is the true and official representative with authority to sign this Agreement and the other documents executed in
connection herewith and bind the Company accordingly, and (iv) this Agreement constitutes, and upon execution and delivery by the
Company of the Shares, each of such instruments will constitute, a legal, valid and binding obligation of the Company enforceable
against the Company in accordance with its terms.

 

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c.            Capitalization.
As of the date hereof, the authorized capital stock of the Company consists of 10,000 shares of Common Stock, $0.0001 par value
per share, of which 1,000 shares will be issued and outstanding. All of such outstanding shares of capital stock are, or upon issuance
will be, duly authorized, validly issued, fully paid and non-assessable. No shares of capital stock of the Company are subject
to preemptive rights or any other similar rights of the shareholders of the Company or any liens or encumbrances imposed through
the actions or failure to act of the Company. The Company, upon request of Investor, will furnish to Investor true and correct
copies of the Company’s Certificate of Incorporation as in effect on the date hereof (“Certificate of Incorporation”),
the Company’s By-laws, as in effect on the date hereof (the “By-laws”) and the Company’s Certificate of
Designation as in effect on the date hereof (“Certificate of Designation”).

 

d.            Issuance
of Shares. The Shares are duly authorized and reserved for issuance and are validly issued, fully paid and non-assessable,
and free from all taxes, liens, claims and encumbrances with respect to the issue thereof and shall not be subject to preemptive
rights or other similar rights of shareholders of the Company and will not impose personal liability upon the holder thereof.

 

e.            Acknowledgment
of Dilution. The Company understands and acknowledges the potentially dilutive effect to the Common Stock upon the issuance
of the Shares. The Company further acknowledges that the Shares are absolute and unconditional regardless of the dilutive effect
that such issuances may have on the ownership interests of other shareholders of the Company.

 

f.             No
Conflicts. The execution, delivery and performance of this Agreement and the consummation by the Company of the transactions
contemplated hereby and will not (i) conflict with or result in a violation of any provision of the Certificate of Incorporation,
By-laws or Certificate of Designation or (ii) violate or conflict with, or result in a breach of any provision of, or constitute
a default (or an event which with notice or lapse of time or both could become a default) under, or give to others any rights of
termination, amendment, acceleration or cancellation of, any agreement, indenture, patent, patent license or instrument to which
the Company or any of its Subsidiaries is a party, or (iii) result in a violation of any law, rule, regulation, order, judgment
or decree (including federal and state securities laws and regulations and regulations of any self-regulatory organizations to
which the Company or its securities are subject) applicable to the Company or any of its Subsidiaries or by which any property
or asset of the Company or any of its Subsidiaries is bound or affected (except for such conflicts, defaults, terminations, amendments,
accelerations, cancellations and violations as would not, individually or in the aggregate, have a Material Adverse Effect). 

 

g.            Intentionally
left blank. 

 

h.            Intentionally
left blank. 

 

i.             Absence
of Litigation. There is no action, suit, claim, proceeding, inquiry or investigation before or by any court, public board,
government agency, self-regulatory organization or body pending or, to the knowledge of the Company or any of its Subsidiaries,
threatened against or affecting the Company or any of its Subsidiaries, or their officers or directors in their capacity as such,
that could have a Material Adverse Effect. 

 

j.             No
Materially Adverse Contracts, Etc. Neither the Company nor any of its Subsidiaries is subject to any charter, corporate or
other legal restriction, or any judgment, decree, order, rule or regulation which in the judgment of the Company’s officers
has or is expected in the future to have a Material Adverse Effect. Neither the Company nor any of its Subsidiaries is a party
to any contract or agreement which in the judgment of the Company’s officers has or is expected to have a Material Adverse
Effect.

 

k.            Tax
Status. The Company and each of its Subsidiaries has made or filed all federal, state and foreign income and all other tax
returns, reports and declarations required by any jurisdiction to which it is subject (unless and only to the extent that the Company
and each of its Subsidiaries has set aside on its books provisions reasonably adequate for the payment of all unpaid and unreported
taxes) and has paid all taxes and other governmental assessments and charges that are material in amount, shown or determined to
be due on such returns, reports and declarations, except those being contested in good faith and has set aside on its books provisions
reasonably adequate for the payment of all taxes for periods subsequent to the periods to which such returns, reports or declarations
apply. 

 

    4

     

    

 

l.             Certain
Transactions. Except for arm’s length transactions pursuant to which the Company or any of its Subsidiaries makes payments
in the ordinary course of business upon terms no less favorable than the Company or any of its Subsidiaries could obtain from third
parties and other than the employment agreements with management as set forth in the Company Materials.

 

m.           Disclosure.
All information relating to or concerning the Company or any of its Subsidiaries set forth in this Agreement in connection with
the transactions contemplated hereby is true and correct in all material respects and the Company has not omitted to state any
material fact necessary in order to make the statements made herein or therein, in light of the circumstances under which they
were made, not misleading. 

 

n.           Intentionally
left blank. 

 

o.           No
Brokers. The Company has taken no action which would give rise to any claim by any person for brokerage commissions, transaction
fees or similar payments relating to this Agreement or the transactions contemplated hereby. 

 

4.            Covenants.

 

a.            Best
Efforts. The parties shall use their best efforts to satisfy timely each of the conditions described in Section 6 and 7 of
this Agreement. 

 

b.           Form
D; Blue Sky Laws. The Company agrees to file a Form D with respect to the Securities as required under Regulation D and to
provide a copy thereof to Investor promptly after such filing. The Company shall, on or before the Closing Date, take such action
as the Company shall reasonably determine is necessary to qualify the Securities for sale to Investor at the applicable closing
pursuant to this Agreement under applicable securities or “blue sky” laws of the states of the United States (or to
obtain an exemption from such qualification), and shall provide evidence of any such action so taken to Investor on or prior to
the Closing Date.

 

5.            Conditions
to the Company’s Obligation to Issue. The obligation of the Company hereunder to issue and sell the Shares to Investor
at the Closing is subject to the satisfaction, at or before the Closing Date of each of the following conditions thereto, provided
that these conditions are for the Company’s sole benefit and may be waived by the Company at any time in its sole discretion:

 

(a)           Investor
shall have executed this Agreement and delivered the same to the Company.

 

(b)           Investor
shall have delivered the Cash Purchase Price in accordance with Section 1(a) above and Investor shall direct its transfer agent
to issue and deliver the Equity Purchase Price within thirty (30) days of the Closing.

 

(c)           The representations
and warranties of the Investor shall be true and correct in all material respects as of the date when made and as of the Closing
Date as though made at that time (except for representations and warranties that speak as of a specific date), and the Investor
shall have performed, satisfied and complied in all material respects with the covenants, agreements and conditions required by
this Agreement to be performed, satisfied or complied with by the Investor at or prior to the Closing Date.

 

    5

     

    

 

(d)           No litigation,
statute, rule, regulation, executive order, decree, ruling or injunction shall have been enacted, entered, promulgated or endorsed
by or in any court or governmental authority of competent jurisdiction or any self-regulatory organization having authority over
the matters contemplated hereby which prohibits the consummation of any of the transactions contemplated by this Agreement.

 

6.            Conditions
to Investor’s Obligation to Purchase. The obligation of Investor hereunder to purchase the Shares at the Closing is subject
to the satisfaction, at or before the Closing Date of each of the following conditions, provided that these conditions are for
Investor’s sole benefit and may be waived by Investor at any time in his sole discretion: 

 

(a)           The
Company shall have executed this Agreement and delivered the same to Investor.

 

(b)           The
Company shall have delivered to Investor the Shares within five business days of the Closing Date.

 

(c)           The
representations and warranties of the Company shall be true and correct in all material respects as of the date when made and as
of the Closing Date as though made at such time (except for representations and warranties that speak as of a specific date) and
the Company shall have performed, satisfied and complied in all material respects with the covenants, agreements and conditions
required by this Agreement to be performed, satisfied or complied with by the Company at or prior to the Closing Date.

 

(d)           No
litigation, statute, rule, regulation, executive order, decree, ruling or injunction shall have been enacted, entered, promulgated
or endorsed by or in any court or governmental authority of competent jurisdiction or any self-regulatory organization having authority
over the matters contemplated hereby which prohibits the consummation of any of the transactions contemplated by this Agreement.

 

(e)           No
event shall have occurred which could reasonably be expected to have a Material Adverse Effect on the Company.

 

7.            Governing
Law; Miscellaneous.

 

a.            Governing
Law. This Agreement shall be governed by and construed in accordance with the laws of the State of New Jersey without regard
to principles of conflicts of laws. Any action brought by either party against the other concerning the transactions contemplated
by this Agreement shall be brought only in the state courts of New Jersey or in the federal courts located in the state and county
of Monmouth. The parties to this Agreement hereby irrevocably waive any objection to jurisdiction and venue of any action instituted
hereunder and shall not assert any defense based on lack of jurisdiction or venue or based upon forum non conveniens. The
Company and Investor waive trial by jury. The prevailing party shall be entitled to recover from the other party its reasonable
attorney’s fees and costs. In the event that any provision of this Agreement or any other agreement delivered in connection herewith
is invalid or unenforceable under any applicable statute or rule of law, then such provision shall be deemed inoperative to the
extent that it may conflict therewith and shall be deemed modified to conform with such statute or rule of law. Any such provision
which may prove invalid or unenforceable under any law shall not affect the validity or enforceability of any other provision of
any agreement. Each party hereby irrevocably waives personal service of process and consents to process being served in any suit,
action or proceeding in connection with this Agreement or any other Transaction Document by mailing a copy thereof via registered
or certified mail or overnight delivery (with evidence of delivery) to such party at the address in effect for notices to it under
this Agreement and agrees that such service shall constitute good and sufficient service of process and notice thereof. Nothing
contained herein shall be deemed to limit in any way any right to serve process in any other manner permitted by law.

 

b.            Counterparts;
Signatures by Facsimile. This Agreement may be executed in one or more counterparts, each of which shall be deemed an original
but all of which shall constitute one and the same agreement and shall become effective when counterparts have been signed by each
party and delivered to the other party. This Agreement, once executed by a party, may be delivered to the other party hereto by
facsimile transmission of a copy of this Agreement bearing the signature of the party so delivering this Agreement.

 

    6

     

    

 

c.            Headings.
The headings of this Agreement are for convenience of reference only and shall not form part of, or affect the interpretation of,
this Agreement.

 

d.            Severability.
In the event that any provision of this Agreement is invalid or unenforceable under any applicable statute or rule of law, then
such provision shall be deemed inoperative to the extent that it may conflict therewith and shall be deemed modified to conform
with such statute or rule of law. Any provision hereof which may prove invalid or unenforceable under any law shall not affect
the validity or enforceability of any other provision hereof.

 

e.             Entire
Agreement; Amendments. This Agreement and the instruments referenced herein contain the entire understanding of the parties
with respect to the matters covered herein and therein and, except as specifically set forth herein or therein, neither the Company
nor Investor makes any representation, warranty, covenant or undertaking with respect to such matters. No provision of this Agreement
may be waived or amended other than by an instrument in writing signed by the majority in interest of Investor.

 

f.             Notices.
All notices, demands, requests, consents, approvals, and other communications required or permitted hereunder shall be in writing
and, unless otherwise specified herein, shall be (i) personally served, (ii) deposited in the mail, registered or certified, return
receipt requested, postage prepaid, (iii) delivered by reputable air courier service with charges prepaid, or (iv) transmitted
by hand delivery, telegram, or facsimile, addressed as set forth below or to such other address as such party shall have specified
most recently by written notice. Any notice or other communication required or permitted to be given hereunder shall be deemed
effective (a) upon hand delivery or delivery by facsimile, with accurate confirmation generated by the transmitting facsimile machine,
at the address or number designated below (if delivered on a business day during normal business hours where such notice is to
be received), or the first business day following such delivery (if delivered other than on a business day during normal business
hours where such notice is to be received) or (b) on the second business day following the date of mailing by express courier service,
fully prepaid, addressed to such address, or upon actual receipt of such mailing, whichever shall first occur. The addresses for
such communications shall be: 

 

If to the
Company, to the address set forth on the signature page

 

If to Investor,
the address as set forth on the signature page.

 

Each party
shall provide notice to the other party of any change in address.

 

g.            Successors
and Assigns. This Agreement shall be binding upon and inure to the benefit of the parties and their successors and assigns.
Neither the Company nor Investor shall assign this Agreement or any rights or obligations hereunder without the prior written consent
of the other. 

 

h.            Third
Party Beneficiaries. This Agreement is intended for the benefit of the parties hereto and their respective permitted successors
and assigns, and is not for the benefit of, nor may any provision hereof be enforced by, any other person.

 

i.             Survival.
The representations and warranties of the Company and the agreements and covenants set forth in this Agreement shall survive the
closing hereunder notwithstanding any due diligence investigation conducted by or on behalf of Investor. The Company agrees to
indemnify and hold harmless each of Investor and all their officers, directors, employees and agents for loss or damage arising
as a result of or related to any breach or alleged breach by the Company of any of its representations, warranties and covenants
set forth in this Agreement or any of its covenants and obligations under this Agreement, including advancement of expenses as
they are incurred.

 

j.             Further
Assurances. Each party shall do and perform, or cause to be done and performed, all such further acts and things, and shall
execute and deliver all such other agreements, certificates, instruments and documents, as the other party may reasonably request
in order to carry out the intent and accomplish the purposes of this Agreement and the consummation of the transactions contemplated
hereby.

 

    7

     

    

 

k.            No
Strict Construction. The language used in this Agreement will be deemed to be the language chosen by the parties to express
their mutual intent, and no rules of strict construction will be applied against any party.

 

l.             Remedies.
The Company acknowledges that a breach by it of its obligations hereunder will cause irreparable harm to Investor by vitiating
the intent and purpose of the transaction contemplated hereby. Accordingly, the Company acknowledges that the remedy at law for
a breach of its obligations under this Agreement will be inadequate and agrees, in the event of a breach or threatened breach by
the Company of the provisions of this Agreement, that Investor shall be entitled, in addition to all other available remedies at
law or in equity, and in addition to the penalties assessable herein, to an injunction or injunctions restraining, preventing or
curing any breach of this Agreement and to enforce specifically the terms and provisions hereof, without the necessity of showing
economic loss and without any bond or other security being required.

 

IN WITNESS WHEREOF, the undersigned Investor
and the Company have caused this Agreement to be duly executed as of the date first above written.

 

GeneExome Technologies Inc.

 

By:/s/ David Jin 

Name: David Jin 

Title: Co-Chief Executive Officer 

Address:

 

83 South Street, Suite 101 

Freehold, New Jersey 07728

 

Avalon GloboCare Corp.

 

By:/s/ Luisa Ingargiola 

Name: Luisa Ingargiola 

Title: Chief Financial Officer

 

Address:

 

83 South Street, Suite 101 

Freehold, New Jersey 07728 

 

    8

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