Document:

EX-10.5

 Exhibit 10.5 

CONSULTING AGREEMENT 

This Consulting Agreement, effective as of February 27, 2016 (“Effective Date”), is by and between Curis, Inc., having a place
of business at 4 Maguire Road, Lexington, MA 02421 (“Curis”), and Jaye Viner (“Consultant”). 
 WHEREAS, Curis desires
to have the benefit of Consultant’s knowledge and experience, and Consultant desires to provide consulting services to Curis as provided in this Agreement; 

NOW, THEREFORE, in consideration of the promises set forth in the Agreement, Curis and Consultant hereby agree as follows: 

1. Term; Termination. The consultation period shall commence on the Effective Date and shall continue until August 31, 2016 (such period, being
referred to as the “Consultation Period”). Curis or Consultant may terminate this Agreement at any time during the Consultation Period with 30 days prior written notice to the other party. Curis may terminate this Agreement at any time,
effective immediately, if the Consultant breaches or threatens to breach the terms of that certain Invention, Non-Disclosure and Non-Competition Agreement, dated August 28, 2013, between Curis and the Consultant. 

Upon termination of this Agreement in accordance with the terms above, the Consultant shall be entitled to payment for services performed and
expenses incurred by Consultant prior to the effective date of termination, subject to the limitation on reimbursement of expenses set forth in Section 3. 

2. Consulting duties. 
  

	(a)	Consultant shall provide Curis or to Curis’ designee, such consulting, advisory and related services to and for Curis as may be reasonably requested from time to time by the Curis’ Chief Executive Officer or
his designee, including, but not limited to, the services specified in the attached Exhibit A, which may revised from time to time upon the mutual written agreement of both parties. 

 

	(b)	All work to be performed by Consultant for Curis shall be under the general supervision of the Chief Executive Officer and/or his designee. 

 

	(c)	Consultant shall devote his best efforts and ability to the performance of the duties attaching to this Agreement, with the Consultant and Curis mutually agreeing on the approximate number of hours that Consultant will
work during any given period, but in no event shall Consultant provide more than 32 hours of consulting services per month. 

 3.
Compensation. In consideration for the services rendered by Consultant to Curis during the term of this Agreement, Curis shall pay Consultant a fee of $200 per hour for any services rendered. Consultant shall invoice Curis on a monthly basis
and such fees will be made in arrears within fifteen (15) days of Curis’ receipt of such invoice. 

 Curis shall reimburse Consultant for reasonable documented out-of-pocket expenses incurred in the performance of
the services hereunder. Consultant shall submit to Curis itemized monthly statements, in a form satisfactory to Curis, of such hours fees and expenses incurred in the previous month. Invoices will be submitted monthly to the following address via
email: accountspayable@curis.com. Notwithstanding the foregoing, Consultant shall not incur total expenses in excess of Five Hundred dollars ($500.00) per month without the prior written approval of Curis. 

4. Status. Consultant’s relation to Curis shall be that of an independent contractor and neither this Agreement nor the services to be rendered
hereunder shall for any purpose whatsoever or in any way or manner create any employer-employee relationship between the parties. Consultant shall not be entitled to any benefits, coverage or privileges, including, without limitation, social
security, unemployment, medical or pension payments, made available to employees of the Curis. Consultant shall not be deemed an agent for any purpose, is not authorized to assume or create any obligation or responsibility, express or implied, on
behalf of, or in the name of, Curis and shall have no authority to bind Curis. 
 5. Inventions, Proprietary Rights and Disclosures. 

 

	(a)	Consultant agrees to disclose promptly to Curis all inventions, discoveries, designs, improvements and all other intellectual property rights (collectively referred to as “Inventions”) made, conceived, reduced
to practice, created, written, designed or developed by Consultant, solely or jointly with others and whether during normal business hours or otherwise, (i) during the Consultation Period if related to the actual or planned business of Curis or
(ii) after the Consultation Period if resulting or directly derived from Confidential Information (as defined below), or perfected in the performance of, or arising out of, the work to be performed by Consultant for Curis, and will maintain
adequate and current written records (in the form of notes, sketches, drawings and as may be specified by Curis), properly corroborated, to document the conception and/or first actual reduction to practice of any Invention. Such written records
shall be available to and remain the sole and exclusive property of Curis at all times. All such Inventions and patents therefor shall be the sole and exclusive property of Curis. Consultant hereby assigns to Curis all Inventions and any and all
related patents, copyrights, trademarks, trade names, and other industrial and intellectual property rights and applications therefor, in the United States and elsewhere and appoints any officer of Curis as his duly authorized attorney to execute,
file, prosecute and protect the same before any government agency, court or authority. Upon the request of Curis and at Curis’s expense, Consultant shall execute such further assignments, documents and other instruments as may be necessary or
desirable to fully and completely assign all Inventions to Curis and to assist Curis in applying for, obtaining and enforcing patents or copyrights or other rights in the United States and in any foreign country with respect to any Invention.
Consultant also hereby waives all claims to moral rights in any Inventions. 

  
 2 

	(b)	Consultant agrees that the services furnished pursuant to the work to be performed hereunder, the data and Inventions generated by the said work and any and all information, data, specifications, techniques, formulae
and processes disclosed by Curis in connection therewith including any and all scientific, technical, trade or business information possessed or obtained by, developed for or given to Curis which is treated by Curis as confidential or proprietary
including, without limitation, formulations, techniques, methodology, assay systems, formulae, chemical structures, procedures, tests, equipment, data, computer software, documentation, reports, know-how, sources of supply, patent positioning,
relationships with consultants and employees, business plans and business developments, financial information, information concerning the existence, scope or activities of any research, development, manufacturing, marketing or other projects of
Curis, and any other confidential or proprietary information about or belonging to Curis’ suppliers, licensors, licensees, partners, affiliates, customers, potential customers or others whether disclosed orally, visually, or in intangible form
to Consultant (collectively referred to as “Confidential Information”) are the property of Curis and are confidential and proprietary to Curis. Consultant agrees that he shall not use Confidential Information for any purpose other than as
advised or directed by Curis regardless of whether such Confidential Information has been furnished or made available to Consultant by Curis or is original with Consultant. Without Curis’ express written consent first obtained, Consultant
agrees that he shall not disclose or make available any Confidential Information to any third party regardless of whether such Confidential Information has been furnished or made available to Consultant by Curis or is original with Consultant.
Consultant shall not discuss the nature of his activities in connection with Curis with anyone except authorized representatives of Curis. At Curis’ request, Consultant shall provide Curis with all Confidential Information furnished to
Consultant by Curis or original with Consultant in connection with his services furnished hereunder which has been reduced to writing and retain no copies thereof. Consultant understands that in receiving Confidential Information, he receives no
right to a license, implied or otherwise, under any patent or other rights now or hereafter owned or controlled by Curis. 

  

	(c)	The foregoing obligations of confidentiality and non-use shall not apply to: 

 (1) information
which is or becomes known to the general public under circumstances involving no breach by Consultant or others of the terms of this Section 5; 

(2) is generally disclosed to third parties by Curis without restriction on such third parties; or 

(3) is approved for release by written authorization of the Board of Directors of Curis. 

However, Confidential Information shall not be deemed within the foregoing exceptions if: 

  
 3 

	 	(i)	specific information is merely embraced by more general information in the public domain or Consultant’s possession, or 

  

	 	(ii)	it constitutes a combination which can be reconstructed from multiple sources in the public domain or Consultant’s possession, none of which shows the whole combination of the Confidential Information.

  

	(d)	Upon termination of this Agreement or at any other time upon request by Curis, Consultant shall promptly deliver to Curis all records, files, memoranda, notes, designs, data, reports, price lists, customer lists,
drawings, plans, computer programs, software, software documentation, sketches, laboratory and research notebooks and other documents (and all copies or reproductions of such materials) relating to the business of Curis or any Confidential
Information received hereunder. 

  

	(e)	Consultant warrants and represents that no trade secrets or other confidential information of any other person, firm, corporation, institution or other entity will be wrongfully disclosed by him to Curis in connection
with any of the services called for hereunder. Consultant further warrants and represents that none of the provisions of this Agreement, nor the services which will be performed by Consultant pursuant to the work to be performed hereunder,
contravenes or is in conflict with any agreement of Consultant with, or obligation to, any other person, firm, corporation, institution or other entity including, without limiting the generality of the foregoing, employment agreements, consulting
agreements, disclosure agreements or agreements for assignment of inventions. Consultant agrees that his services to other enterprises may result in a conflict of interest with his obligations to Curis under this Agreement, and agrees to inform
Curis of his services to other enterprises and, in the case of conflict of interest, to immediately inform Curis and resolve the conflict in a mutually satisfactory manner. 

 

	(f)	Consultant hereby acknowledges that the United States securities laws prohibit any person who has material, non-public information from purchasing or selling the securities of Curis or the securities of any company
doing business with Curis or from communicating such information to any other person under circumstances in which it is reasonably foreseeable that such person is likely to purchase or sell such securities. 

 

	(g)	Consultant acknowledges that (a) the provisions of this Agreement are reasonable and necessary to protect the legitimate interests of Curis, (b) any violations of this Agreement will result in irreparable
injury to Curis and that damages at law would not be reasonable or adequate compensation to Curis for a violation of this Agreement and (c) Curis shall be entitled, in addition to any other right or remedy available in law or in equity, to the
right to obtain an injunction from a court of competent jurisdiction restraining such breach or threatened breach and to specific performance of any such provision of this Agreement. The parties further agree that no bond or other security shall be
required in obtaining such equitable relief and each party hereby consents to the issuance of such injunction and to the ordering of specific performance. 

  
 4 

 6. Survival of Provisions. The provisions of Section 5 hereof shall survive the termination or
expiration of this Agreement. 
 7. Assignability and Binding Effect. This Agreement shall be binding upon, and inure to the benefit of, both parties
and their respective successors and assigns, including any corporation with which Curis may merge or consolidate or to which Curis may assign substantially all of its assets or that portion of its business to which this Agreement pertains, provided,
however, that the obligations of the Consultant are personal and shall not be assigned by him. 
 8. Headings. The paragraph headings contained
herein are included solely for convenience of reference and shall not control or affect the meaning or interpretation of any of the provisions of this Agreement. 

9. Notices. Any notices or other communications hereunder by either party shall be in writing and shall be deemed to have been duly given if delivered
personally to the other party or sent by registered or certified mail, return receipt requested, to the other party at the following addresses: 
  

			
	If to Curis:	  	 Curis, Inc.
 4 Maguire Road

Lexington, MA 02421
 Attention: Legal Department

		
	If to Consultant:	  	 Dr. Jaye Viner
 [Address 1]

[Address 2]

[Cell:                 ]

[Email:              ]

 or at such other address as such other party may designate in conformity with the foregoing. 

10. Entire Agreement; Modification; Severability. This document sets forth the entire Agreement between the parties hereto with respect to the subject
matter hereof. This Agreement shall not be changed or modified in any manner except by an instrument signed by the Company and the Consultant, which document shall make specific reference to this Agreement and shall express the plan or intention to
modify same. In the event that any provision of this Agreement shall be invalid, illegal or otherwise unenforceable, the validity, legality and enforceability of the remaining provisions shall in no way be affected or impaired thereby. 

11. Counterparts. This Agreement may be executed in any number of counterparts, each of which shall be deemed an original, but all of which together
shall constitute one and the same instrument. 

  
 5 

 IN WITNESS WHEREOF, this Agreement is executed under seal by both parties and deemed to be
governed by the laws of the Commonwealth of Massachusetts, exclusive of its conflicts of law principles. 
  

									
	CURIS, INC.	 		 	CONSULTANT:
					
	By:	 	/s/ Ali Fattaey	 		 	By:	 	/s/ Jaye Viner
					
	Name: 	 	Ali Fattaey, Ph.D.	 		 	Name: 	 	Jaye Viner
					
	Title:	 	President & CEO	 		 		 	
					
	Date:	 	February 29, 2016	 		 	Date:	 	February 25, 2016

  
 6 

 Exhibit A 

During the term of this agreement, Consultant shall provide to Curis or to Curis’ designee consulting services in the area of Clinical Development at
such times and places as Curis and Consultant mutually agree. 
 Curis shall give Consultant reasonable advance notice of any service required. Consultant
agrees to furnish Curis with written reports with respect to such consulting services if and when requested by Curis. 

  
 7EX-10.6

 Exhibit 10.6 
  

 
 VIA HAND DELIVERY 

February 26, 2016 
 Jaye Viner, M.D. 

[Address 1] 
 [Address 2] 

Dear Jaye: 
 In connection with the termination
of your employment with Curis, Inc. (the “Company”), the Company and you have agreed that you will remain employed with the Company through February 26, 2016. You are eligible to receive (i) a payment under the Company’s
2015 short-term incentive plan as described in paragraph 2 below and (ii) the severance benefits described in paragraph 3 below if you sign and return this letter agreement to me no earlier than the Termination Date and no later than 60 days
following your Termination Date and it becomes binding between you and the Company on the eighth day following execution. By signing and returning this letter agreement and not revoking your acceptance, you will be entering into a binding agreement
with the Company and will be agreeing to the terms and conditions set forth in the numbered paragraphs below, including the release of claims set forth in paragraph 4. Therefore, you are advised to consult with an attorney before signing this letter
agreement and the Company is providing you with sixty (60) days from your Termination Date to do so pursuant to the terms of your At-Will Employment Agreement dated August 28, 2013 (“At-Will Employment Agreement”). If you sign
this letter agreement, you may change your mind and revoke your agreement during the seven (7) day period after you have signed it by notifying me in writing. If you do not so revoke, this letter agreement will become a binding agreement
between you and the Company upon the expiration of the seven (7) day period. 
 If you choose not to sign and return this letter
agreement by 60 days following your actual Termination Date or if you timely revoke your acceptance in writing, you shall not receive the severance benefits from the Company described herein. You will, however, receive payment on your Termination
Date, as defined below, for your final wages, any unused vacation time accrued through the Termination Date, and the payment under the Company’s 2015 short-term incentive plan described in paragraph 2. You may also, if eligible, elect to
continue receiving group medical insurance pursuant to the federal “COBRA” law, 29 U.S.C. § 1161 et seq. Please consult the COBRA materials to be provided by the Company under separate cover for details regarding these
benefits. Further, pursuant to the option agreements evidencing the awards under the Amended and Restated 2010 Stock Incentive Plan, you have up to ninety (90) days after your Termination Date to exercise any vested stock option rights you may
have as provided for by the Plan. All other unvested options will be cancelled on your Termination Date.  

 The following numbered paragraphs set forth the terms and conditions that will apply if you
timely sign and return this letter agreement and do not revoke it in writing within the seven (7) day period. 
 1. Termination
Date – Your expected effective date of termination from the Company will be February 26, 2016, although this date can be changed by either you or the Company upon mutual agreement (the “Termination Date”). The Termination
Date will therefore be your actual final day of employment at the Company. As of the Termination Date, all salary payments from the Company will cease and any benefits you had as of the Termination Date under Company-provided benefit plans,
programs, or practices will terminate, except as required by federal or state law. 
 2. Bonus Payments – The Company has
made a payment to you under the 2015 short-term incentive plan in an amount equal to 47% of your target bonus amount, which is equal to $69,468, less all applicable taxes and withholdings. In recognition of your contributions to Curis during this
transition period, the Company will also make a payment to you in an amount equal to $30,532, less all applicable taxes and withholdings. The Company will make this payment on or before your last day of employment with the Company, which is agreed
to be February 26, 2016. 
 3. Description of Severance Benefits – If you timely sign and return this letter
agreement by 60 days following your actual Termination Date and do not revoke your acceptance thereafter, the Company will provide you with the following severance benefits (the “severance benefits”): 

a. Severance Pay. The Company will pay to you $211,150, less all applicable taxes and withholdings, as severance pay (an amount
equivalent to one-half (1/2) of your current annual base salary). This severance pay will be paid in installments in accordance with the Company’s normal payroll practices, but in no event shall payment begin earlier than the eighth (8th) day after your execution and timely return of this letter agreement. 
 b. COBRA
Benefits. Should you timely elect and be eligible to continue receiving group medical insurance pursuant to the “COBRA” law, the Company will, for six (6) months following your Termination Date, continue to pay the share of the
premium for such coverage that is paid by the Company for active and similarly-situated employees who receive the same type of coverage. The remaining balance of any premium costs shall be paid by you on a monthly basis for as long as, and to the
extent that, you remain eligible for COBRA continuation. You should consult the COBRA materials to be provided by the Company under separate cover for details regarding these benefits. 

  
 2 

 By entering into this letter agreement, you specifically agree and acknowledge that by offering
you the severance benefits, the Company has fulfilled all of its obligations to you under the At-Will Employment Agreement. You acknowledge the payments and benefits set forth in this letter agreement, together with payments and benefits previously
provided to you by Curis, are the only payments and benefits you will receive in connection with your employment and termination. You further agree and acknowledge that you would otherwise not have been entitled to payments and benefits set forth in
this paragraph in the absence of this letter agreement. 
 4. Release – In consideration of the severance benefits
described above, which you acknowledge you would not otherwise be entitled to receive, you hereby fully, forever, irrevocably and unconditionally release, remise and discharge the Company, its affiliates, subsidiaries, parent companies,
predecessors, and successors, and all of their respective past and present officers, directors, stockholders, partners, members, employees, agents, representatives, plan administrators, attorneys, insurers and fiduciaries (each in their individual
and corporate capacities) (collectively, the “Released Parties”) from any and all claims, charges, complaints, demands, actions, causes of action, suits, rights, debts, sums of money, costs, accounts, reckonings, covenants, contracts,
agreements, promises, doings, omissions, damages, executions, obligations, liabilities, and expenses (including attorneys’ fees and costs), of every kind and nature that you ever had or now have against any or all of the Released Parties,
including, but not limited to, any and all claims arising out of or relating to your employment with and/or separation from the Company, including, but not limited to, all claims under Title VII of the Civil Rights Act of 1964, 42 U.S.C. §
2000e et seq., the Americans With Disabilities Act of 1990, 42 U.S.C. § 12101 et seq., the Age Discrimination in Employment Act, 29 U.S.C. § 621 et seq., the Genetic Information Nondiscrimination Act of 2008, 42 U.S.C.
§ 2000ff et seq., the Family and Medical Leave Act, 29 U.S.C. § 2601 et seq., the Worker Adjustment and Retraining Notification Act (“WARN”), 29 U.S.C. § 2101 et seq., the Rehabilitation Act of 1973, 29
U.S.C. § 701 et seq., Executive Order 11246, Executive Order 11141, the Fair Credit Reporting Act, 15 U.S.C. § 1681 et seq., and the Employee Retirement Income Security Act of 1974 (“ERISA”), 29 U.S.C. § 1001
et seq., all as amended; all claims arising out of the Massachusetts Fair Employment Practices Act., Mass. Gen. Laws ch. 151B, § 1 et seq., the Massachusetts Civil Rights Act, Mass. Gen. Laws ch. 12, §§ 11H and 11I, the
Massachusetts Equal Rights Act, Mass. Gen. Laws. ch. 93, § 102 and Mass. Gen. Laws ch. 214, § 1C, the Massachusetts Labor and Industries Act, Mass. Gen. Laws ch. 149, § 1 et seq., the Massachusetts Wage Act, Mass. Gen. Laws ch.
149 § 148 et seq., Mass. Gen. Laws ch. 214, § 1B (Massachusetts right of privacy law), the Massachusetts Maternity Leave Act, Mass. Gen. Laws ch. 149, § 105D, and the Massachusetts Small Necessities Leave Act, Mass. Gen. Laws
ch. 149, § 52D, all as amended; all common law claims including, but not limited to, actions in defamation, intentional infliction of emotional distress, misrepresentation, fraud, wrongful discharge, and breach of contract (including, without
limitation, all claims arising out of or related to your At-Will Employment Agreement; all claims to any non-vested ownership interest in the Company, contractual or otherwise; and any claim or damage arising out of your employment with and/or
separation from the Company (including a claim for retaliation) under any common law theory or any federal, state or local statute or ordinance not expressly referenced above; provided, however, that nothing in this letter agreement (a)

  
 3 

 
limits any rights you may have to indemnification pursuant to Section 13 of the At-Will Employment Agreement (which is the only section of the At-Will Employment Agreement that remains in
force and effect) or otherwise; or (b) prevents you from filing a charge with, cooperating with, or participating in any proceeding before the U.S. Equal Employment Opportunity Commission (“EEOC”) or a state fair employment practices
agency (except that you acknowledge that you may not recover any monetary benefits in connection with any such claim, charge or proceeding brought against any of the Released Parties, regardless of who filed or initiated any such complaint or
charge). Additionally, for the avoidance of doubt, nothing in this agreement shall prohibit you from communicating with a government agency, regulator or legal authority concerning any possible violations of federal or state law or regulation. You,
however, are not authorized to share communications covered and protected from disclosure by the corporation’s attorney-client privilege. 

5. Continuing Obligations – You acknowledge and reaffirm your obligation to keep confidential and not to disclose any and
all non-public information concerning the Company that you acquired during the course of your employment with the Company, including, but not limited to, any non-public information concerning the Company’s business affairs, business prospects,
and financial condition. You further acknowledge and reaffirm your obligations set forth in the Invention, Non-Disclosure and Non-Competition Agreement (the “Non-Competition Agreement”) you executed on August 28, 2013 for the benefit
of the Company, which Non-Competition Agreement remains in full force and effect, and is attached hereto as “Exhibit A”. 
 6.
Non-Disparagement – You understand and agree that as a condition of your receipt of the severance benefits herein described, you shall not make any false, disparaging or derogatory statements to any person or entity, including any
media outlet, regarding the Company or any of its directors, officers, employees, agents or representatives or about the Company’s business affairs or financial condition. You agree, to the extent permitted by law, that you will not, at any
time after the date hereof, make any remarks or comments, orally or in writing, to customers, potential customers, partners, suppliers, employees, managers, supervisors, or others, which reasonably could be construed to be derogatory or disparaging
to Curis or any of its parent corporations, divisions, subsidiaries, affiliates, shareholders, officers, directors, employees, managers, supervisors, attorneys or agents, or which could reasonably be anticipated to be damaging or injurious to
Curis’s reputation or good will or to the reputation or good will of any person associated with Curis. Notwithstanding the above, the non-disparagement obligation shall not prohibit you from testifying truthfully in any legal proceeding. 

7. Continued Assistance –You agree that after the Termination Date you will provide all reasonable cooperation to the
Company, including but not limited to, assisting the Company in transitioning your job duties, assisting the Company in defending against and/or prosecuting any litigation or threatened litigation, and performing any other tasks as reasonably
requested by the Company. 
 8. Return of Company Property – You confirm that you have returned (or not later than the
Termination Date you will return) to the Company all keys, files, records (and 

  
 4 

 
copies thereof), equipment (including, but not limited to, computer hardware, software and printers, wireless handheld devices, cellular phones, pagers, etc.), Company identification, and any
other Company-owned property in your possession or control and have left intact all electronic Company documents, including but not limited to those that you developed or helped to develop during your employment. You further confirm that you have
cancelled all accounts for your benefit, if any, in the Company’s name, including but not limited to, credit cards, telephone charge cards, cellular phone and/or pager accounts, and computer accounts. 

9. Business Expenses and Final Compensation – You acknowledge that you have been reimbursed by the Company for all business
expenses incurred in conjunction with the performance of your employment and that no other reimbursements are owed to you. You further acknowledge that you have received payment in full for all services rendered in conjunction with your employment
by the Company, including payment for all wages, bonuses, and accrued, unused vacation time, and that no other compensation is owed to you except as provided herein. You further acknowledge that you are unaware of any facts that would support a
claim against any of the Released Parties for violation of the Fair Labor Standards Act. You further acknowledge that you have been granted by Curis all requested paid and/or unpaid leave to which you may have been entitled. 

10. Amendment and Waiver – This letter agreement shall be binding upon the parties and may not be modified in any manner,
except by an instrument in writing of concurrent or subsequent date signed by duly authorized representatives of the parties hereto. This letter agreement is binding upon and shall inure to the benefit of the parties and their respective agents,
assigns, heirs, executors, successors and administrators. No delay or omission by the Company in exercising any right under this letter agreement shall operate as a waiver of that or any other right. A waiver or consent given by the Company on any
one occasion shall be effective only in that instance and shall not be construed as a bar to or waiver of any right on any other occasion. 

11. Validity – Should any provision of this letter agreement be declared or be determined by any court of competent
jurisdiction to be illegal or invalid, the validity of the remaining parts, terms or provisions shall not be affected thereby and said illegal or invalid part, term or provision shall be deemed not to be a part of this letter agreement. In the event
the Release provision of this letter agreement is found to be invalid, illegal, and/or unenforceable, you agree to provide Curis with a full and General Release that is not invalid, illegal and/or unenforceable, without payment of additional
consideration. 
 12. Confidentiality – To the extent permitted by law, you understand and agree that as a condition of
your receipt of the severance benefits herein described, the terms and contents of this letter agreement, and the contents of the negotiations and discussions resulting in this letter agreement, shall be maintained as confidential by you and your
agents and representatives (such term shall include your immediate family members, attorneys and financial advisors) and shall not be disclosed except as otherwise agreed to in writing by the Company. 

  
 5 

 13. Nature of Agreement – You understand and agree that this letter agreement
is a severance agreement and does not constitute an admission of liability or wrongdoing on the part of the Company. 
 14.
Acknowledgments –You acknowledge that you have been given sixty (60) days to consider this letter agreement, and that the Company is hereby advising you to consult with an attorney of your own choosing prior to signing this
letter agreement. You understand that you may revoke this letter agreement for a period of seven (7) days after you sign this letter agreement by notifying me in writing, and the letter agreement shall not be effective or enforceable until the
expiration of this seven (7) day revocation period. In the event that you execute this letter agreement in less than sixty (60) days after the date it was delivered to you, you acknowledge that such decision is entirely voluntary and with
full knowledge that you had the opportunity to consider this letter agreement for the entire sixty (60) day period and that you are waiving your right to consider this agreement for the entire sixty (60) day period. 

15. Voluntary Assent – You affirm that no other promises or agreements of any kind have been made to or with you by any
person or entity whatsoever to cause you to sign this letter agreement, and that you fully understand the meaning and intent of this letter agreement. You state and represent that you have had an opportunity to fully discuss and review the terms of
this letter agreement with an attorney. You further state and represent that you have carefully read this letter agreement, understand the contents herein, freely and voluntarily assent to all of the terms and conditions hereof, and sign your name
of your own free act. 
 16. Applicable Law – This letter agreement shall be interpreted and construed by the laws of the
Commonwealth of Massachusetts, without regard to conflict of laws provisions. You hereby irrevocably submit to and acknowledge and recognize the jurisdiction of the courts of the Commonwealth of Massachusetts or if appropriate, a federal court
located in the Commonwealth of Massachusetts (which courts, for purposes of this letter agreement, are the only courts of competent jurisdiction), over any suit, action or other proceeding arising out of, under or in connection with this letter
agreement or the subject matter hereof. 
 17. Entire Agreement – This letter agreement and any attachments hereto
contains and constitutes the entire understanding and agreement between the parties hereto with respect to your severance benefits and the settlement of claims against the Company and cancels all previous oral and written negotiations, agreements,
and commitments in connection therewith. Nothing in this paragraph, however, shall modify, cancel or supersede your obligations set forth in paragraph 4 above. 

18. Tax Acknowledgement – In connection with the severance benefits provided to you pursuant to this letter agreement, the
Company shall withhold and remit to the tax authorities the amounts required under applicable law, and you shall be responsible for all applicable taxes with respect to such severance benefits under applicable law. You acknowledge that you are not
relying upon the advice or representation of the Company with respect to the tax treatment of any of the severance benefits set forth in paragraph 2 of this letter agreement. 

  
 6 

 19. Company Affiliation – You agree that, following the Termination Date, you
will not hold yourself out as an officer, employee, or otherwise as a representative of the Company, and you agree to update any directory information that indicates you are currently affiliated with the Company. Without limiting the foregoing, you
confirm that, within five (5) days of the Termination Date, you will update any and all social media accounts (including, without limitation, LinkedIn, Facebook, Twitter and Four Square) to reflect that you are no longer employed with the
Company. 
 If you have any questions about the matters covered in this letter agreement, please call me. 

 

			
	Very truly yours,
		
	By:	 	/s/ Ali Fattaey
		 	 Ali Fattaey, Ph.D.
 President and Chief
Executive Officer

 I hereby agree to the terms and conditions set forth above. I have been given sixty (60) days to
consider this letter agreement, and I have chosen to execute this on the date below. I intend that this letter agreement will become a binding agreement between me and the Company if I do not revoke my acceptance in seven (7) days. 

 

					
	 /s/ Jaye Viner
	 		  	 March 31, 2016

	Jaye Viner, M.D.	 		  	Date

  
 7 

 Exhibit A 

Invention, Non-Disclosure and Non-Competition Agreement 

  
 8

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00258-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00258-of-00352.parquet"}]]