Document:

EX-4.2

 Exhibit 4.2 
  

 
 ENDOLOGIX, INC. 

as Issuer 
 AND 

WELLS FARGO BANK, NATIONAL ASSOCIATION 

as Trustee 
  

 
 First
Supplemental Indenture 
 Dated as of December 10, 2013 

to Indenture 
 Dated as of
December 10, 2013 
  
  

2.25% Convertible Senior Notes due 2018 
  

 

 TABLE OF CONTENTS 

 

							
	 	 	 	  	Page	 
	
	ARTICLE 1	  
	DEFINITIONS AND OTHER PROVISIONS OF GENERAL APPLICATION	  
			
	 Section 1.01.
	 	Scope of Supplemental Indenture	  	 	2	  
	 Section 1.02.
	 	Definitions	  	 	2	  
	 Section 1.03.
	 	Section References	  	 	11	  
	
	ARTICLE 2	  
	THE NOTES	  
			
	 Section 2.01.
	 	Designation, Amount and Issuance of Notes	  	 	11	  
	 Section 2.02.
	 	Form of the Notes	  	 	11	  
	 Section 2.03.
	 	Date and Denomination of Notes; Payment at the Stated Maturity Date; Payment of Interest	  	 	12	  
	 Section 2.04.
	 	Registrar, Paying Agent and Conversion Agent	  	 	12	  
	 Section 2.05.
	 	Registration of Transfer and Exchange	  	 	13	  
	 Section 2.06.
	 	Global Securities	  	 	13	  
	 Section 2.07.
	 	Purchase and Cancellation	  	 	14	  
	 Section 2.08.
	 	Additional Notes	  	 	15	  
	 Section 2.09.
	 	Mutilated, Destroyed, Lost or Stolen Notes	  	 	15	  
	
	ARTICLE 3	  
	PARTICULAR COVENANTS OF THE COMPANY	  
			
	 Section 3.01.
	 	Covenants in Original Indenture	  	 	15	  
	 Section 3.02.
	 	[Reserved]	  	 	15	  
	 Section 3.03.
	 	Compliance Certificate	  	 	15	  
	 Section 3.04.
	 	Further Instruments and Acts	  	 	15	  
	
	ARTICLE 4	  
	REPURCHASE OF NOTES	  
			
	 Section 4.01.
	 	Right To Require Repurchase Upon a Fundamental Change	  	 	16	  
	
	ARTICLE 5	  
	CONVERSION	  
			
	 Section 5.01.
	 	Conversion Privilege and Conversion Rate	  	 	19	  
	 Section 5.02.
	 	Conversion Rate Adjustment Upon Certain Make-Whole Adjustment Events	  	 	23	  
	 Section 5.03.
	 	Exercise of Conversion Privilege	  	 	25	  
	 Section 5.04.
	 	Settlement of Conversion Obligation	  	 	25	  

  
 i 

							
	 Section 5.05.
	  	Fractions of Shares	  	 	28	  
	 Section 5.06.
	  	Adjustment of Conversion Rate	  	 	29	  
	 Section 5.07.
	  	Notice of Adjustments of Conversion Rate	  	 	38	  
	 Section 5.08.
	  	Company To Reserve Common Stock	  	 	38	  
	 Section 5.09.
	  	Taxes on Conversions	  	 	38	  
	 Section 5.10.
	  	Certain Covenants	  	 	39	  
	 Section 5.11.
	  	Cancellation of Converted Notes	  	 	39	  
	 Section 5.12.
	  	Provision in Case of Effect of Reclassification, Consolidation, Merger or Sale	  	 	39	  
	 Section 5.13.
	  	Responsibility of Trustee for Conversion Provisions	  	 	41	  
	 Section 5.14.
	  	Notice to Holders Prior to Certain Actions	  	 	41	  
	 Section 5.15.
	  	Stockholder Rights Plan	  	 	42	  
	
	ARTICLE 6	  
			
	 Section 6.01.
	  	Original Indenture	  	 	42	  
	 Section 6.02.
	  	Redemption	  	 	42	  
	 Section 6.03.
	  	Notice of Optional Redemption; Selection of Notes.	  	 	42	  
	 Section 6.04.
	  	Payment of Notes Called for Redemption	  	 	44	  
	 Section 6.05.
	  	Restrictions on Redemption	  	 	44	  
	 Section 6.06.
	  	No Sinking Fund	  	 	44	  
	
	ARTICLE 7	  
	EVENTS OF DEFAULT; REMEDIES	  
			
	 Section 7.01.
	  	Original Indenture	  	 	45	  
	 Section 7.02.
	  	Events of Default	  	 	45	  
	 Section 7.03.
	  	Acceleration of Maturity; Rescission and Annulment	  	 	46	  
	 Section 7.04.
	  	Limitation on Suits	  	 	48	  
	 Section 7.05.
	  	Unconditional Right of Holders To Receive Payment	  	 	49	  
	 Section 7.06.
	  	Waiver of Defaults and Events of Default	  	 	49	  
	 Section 7.07.
	  	Undertaking for Costs	  	 	49	  
	 Section 7.08.
	  	Waiver of Stay or Extension Laws	  	 	49	  
	
	ARTICLE 8	  
	CONSOLIDATION, MERGER, CONVEYANCE, TRANSFER OR LEASE	  
			
	 Section 8.01.
	  	Original Indenture	  	 	50	  
	 Section 8.02.
	  	Consolidation, Merger and Sale of Assets	  	 	50	  
	 Section 8.03.
	  	Successor Substituted	  	 	50	  
	
	ARTICLE 9	  
	REPORTS BY COMPANY	  
			
	 Section 9.01.
	  	Reports by Company.	  	 	51	  

  
 ii 

							
	ARTICLE 10	  
	SATISFACTION AND DISCHARGE	  
	 Section 10.01.
	 	Original Indenture	  	 	51	  
	 Section 10.02.
	 	Discharge of Indenture	  	 	51	  
	 Section 10.03.
	 	Deposited Monies and Shares To Be Held in Trust by Trustee	  	 	52	  
	 Section 10.04.
	 	Paying Agent or Conversion Agent To Repay Monies and Shares Held	  	 	52	  
	 Section 10.05.
	 	Reinstatement	  	 	53	  
	
	ARTICLE 11	  
	SUPPLEMENTAL INDENTURES	  
			
	 Section 11.01.
	 	Supplemental Indentures Without Consent of Holders	  	 	53	  
	 Section 11.02.
	 	Supplemental Indentures with Consent of Holders	  	 	54	  
	
	ARTICLE 12	  
	MISCELLANEOUS	  
			
	 Section 12.01.
	 	Successors	  	 	55	  
	 Section 12.02.
	 	Multiple Originals	  	 	55	  
	 Section 12.03.
	 	Calculations	  	 	55	  
	 Section 12.04.
	 	Benefits of Supplemental Indenture	  	 	56	  
	 Section 12.05.
	 	Withholding Taxes.	  	 	56	  
	 Section 12.06.
	 	Waiver of Jury Trial	  	 	56	  
	 Section 12.07.
	 	Governing Law	  	 	56	  

 Schedule A Make-Whole Table 

EXHIBITS 
 Exhibit A – Form of
Security 

  
 iii 

 FIRST SUPPLEMENTAL INDENTURE, dated as of December 10, 2013, between Endologix, Inc., a
corporation duly organized and existing under the laws of the State of Delaware, as issuer (the “Company”), having its principal office at 11 Studebaker, Irvine, California 92618, and Wells Fargo Bank, National Association, as
trustee (the “Trustee”) to the Indenture dated as of December 10, 2013, between the Company and the Trustee (the “Original Indenture”; the Original Indenture as amended and supplemented hereby and as it may be
further amended and supplemented in accordance herewith and therewith, with respect to the Notes, the “Indenture”). 

RECITALS OF THE COMPANY 

WHEREAS, the Company executed and delivered the Original Indenture to the Trustee to provide for, among other things, the issuance, from time
to time, of the Company’s Securities, in an unlimited aggregate principal amount, in one or more series to be established by the Company under, and authenticated and delivered as provided in, the Original Indenture; 

WHEREAS, Sections 2.1 and 2.2 of the Original Indenture provide for the Company to establish Securities of any series pursuant to a
supplemental indenture, and Section 9.1(e) of the Original Indenture provides for the Company and the Trustee to enter into any such supplemental indenture to provide for the issuance of and establish the form and terms and conditions of
Securities of any series as permitted by the Original Indenture; 
 WHEREAS, the Board of Directors has duly adopted resolutions authorizing
the Company to execute and deliver this Supplemental Indenture; 
 WHEREAS, pursuant to the terms of the Original Indenture, the Company
desires to provide for the establishment of a new series of its Securities to be known as its “2.25% Convertible Senior Notes due 2018” (each, a “Note” and, collectively, the “Notes”) the form and
substance of the Notes and the terms, provisions and conditions thereof to be set forth as provided in the Original Indenture and this Supplemental Indenture; and 

WHEREAS, all things necessary to make the Notes, when executed by the Company and authenticated and delivered hereunder and duly issued by the
Company, the valid and legally binding obligations of the Company, and to make this Supplemental Indenture a valid and legally binding agreement of the Company, in accordance with the terms of the Notes and this Supplemental Indenture, have been
done; 

 NOW, THEREFORE, THIS SUPPLEMENTAL INDENTURE WITNESSETH, for and in consideration of the premises
and the purchases of the Notes by the Holders thereof, it is mutually agreed, for the benefit of the Company and the equal and proportionate benefit of all Holders of the Notes, as follows: 

ARTICLE 1 

DEFINITIONS AND OTHER PROVISIONS OF GENERAL
APPLICATION 
 Section 1.01. Scope of Supplemental Indenture. The changes, modifications and supplements to the
Original Indenture effected by this Supplemental Indenture shall be applicable only with respect to, and shall only govern the terms of, the Notes, and shall not apply to any other Securities that may be issued under the Original Indenture unless a
supplemental indenture with respect to such other Securities specifically incorporates such changes, modifications and supplements. With respect to the Notes, the provisions of this Supplemental Indenture shall supplement and, to the extent they are
inconsistent therewith, supersede any corresponding provisions in the Original Indenture. 
 Section 1.02. Definitions. For all
purposes of the Indenture, except as otherwise expressly provided or unless the context otherwise requires: 
 (i) the terms
defined in this Article 1 have the meanings assigned to them in this Article and include the plural as well as the singular; 

(ii) all words, terms and phrases used in this Supplemental Indenture and defined in the Original Indenture (but not otherwise
defined herein) shall have the same meanings as in the Original Indenture; 
 (iii) all other terms used herein that are
defined in the Trust Indenture Act, either directly or by reference therein, have the meanings assigned to them therein; 

(iv) all accounting terms not otherwise defined herein have the meanings assigned to them in accordance with GAAP; and 

(v) the words “herein,” “hereof’ and “hereunder” and other words of similar import refer to this
Supplemental Indenture as a whole and not to any particular Article, Section or other subdivision. 
 “Additional Interest”
has the meaning specified in Section 7.03. 
 “Additional Notes” has the meaning specified in Section 2.08. 

“Additional Shares” has the meaning specified in Section 5.02(a). 

“Averaging Period” has the meaning specified in Section 5.06(e). 

  
 2 

 “Bid Solicitation Agent” means, initially, the Trustee, or any agent the Company
may appoint in the future (which may be the Company) to determine a Trading Price for the Notes as may be required pursuant to Section 5.01(a)(ii). 

“Business Day” means any day other than (x) a Saturday, (y) a Sunday or (z) a day on which state or federally
chartered banking institutions in New York, New York are not required to be open. 
 “Capital Stock” means any and all
shares, interests, participations, rights or other equivalents (however designated) of corporate stock and limited liability company interests and, with respect to partnerships, partnership interests (whether general or limited) and any other
interest or participation that confers on a Person the right to receive a share of the profits and losses of, or distributions of assets of, such partnership. 

“Cash Settlement” has the meaning specified in Section 5.04(a). 

A “Change in Control” will be deemed to have occurred if any of the following occurs after the Issue Date: 

(1) any “person” or “group” within the meaning of Section 13(d) under the Exchange Act files a Schedule TO or any
schedule, form or report under the Exchange Act disclosing that such person or group has become the direct or indirect “beneficial owner,” as defined in Rule 13d-3 under the Exchange Act, of, shares of the Company’s voting stock
representing 50% or more of the total voting power of all outstanding classes of the Company’s voting stock entitled to vote generally in elections of directors; 

(2) the consummation of (A) any recapitalization, reclassification or change of Common Stock (other than changes resulting from a
subdivision or combination) as a result of which the Common Stock would be converted into, or exchanged for, stock, other securities, other property or assets; (B) any share exchange, consolidation, merger or similar transaction involving the
Company pursuant to which the Common Stock will be converted into cash, securities or other property; or (C) any sale, lease or other transfer in one transaction or a series of transactions of all or substantially all of the consolidated assets
of the Company and its Subsidiaries, taken as a whole, to any Person other than one of the Company’s wholly-owned Subsidiaries; provided that a transaction described in clauses (A) or (B) above (i) pursuant to which the
persons that “beneficially owned,” directly or indirectly, the shares of the Company’s voting stock immediately prior to such transaction “beneficially own,” directly or indirectly, shares of voting stock representing at
least a majority of the total voting power of all outstanding classes of voting stock of the surviving or transferee Person and such holders’ proportional voting power immediately after such transaction vis-à-vis each other with respect
to the securities they receive in such transaction will be in substantially the same proportions as their respective voting power vis-à-vis each other immediately prior to such transaction, or (ii) effected solely to change the
Company’s jurisdiction of incorporation or to form a holding company for the Company and that results in a share exchange or reclassification or similar exchange of the outstanding Common Stock solely into shares of common stock or other common
equity interests of the surviving entity, in either case of clauses (i) or (ii), shall not constitute a “Change in Control”; or 

  
 3 

 (3) the holders of the Company’s Capital Stock approve any plan or proposal for the
liquidation or dissolution of the Company (whether or not otherwise in compliance with the Indenture). 
 Notwithstanding the foregoing, a
Change in Control shall not be deemed to have occurred if at least 90% of the consideration paid for Common Stock in a transaction or transactions described in clause (2) of this definition, excluding cash payments for any fractional share and
cash payments made pursuant to dissenters’ appraisal rights, consists of shares of common stock (or other common equity interests or depositary receipts, or similar certificates, representing common equity interests) traded on The New York
Stock Exchange, The NASDAQ Global Select Market or The NASDAQ Global Market (or any of their respective successors), or will be so traded immediately following such transaction, and, as a result therefrom, such consideration becomes the Reference
Property for the Notes pursuant to Section 5.12 or any supplemental indenture executed pursuant to such Section. 
 “close of
business” means 5:00 p.m., New York City time. 
 “Closing Sale Price” of the Common Stock on any date means the
closing per share sale price (or, if no closing sale price is reported, the average of the bid and ask prices or, if more than one in either case, the average of the average bid and the average ask prices) at 4:00 p.m. (New York City time) on
such date as reported in composite transactions for The NASDAQ Global Select Market or, if the Common Stock is not listed on The NASDAQ Global Select Market, the principal U.S. national or regional securities exchange on which the Common Stock
is listed for trading or, if the Common Stock is not listed on a U.S. national or regional securities exchange, as reported by OTC Markets Group Inc. at 4:00 p.m. (New York City time) on such date (or in either case the then-standard closing
time for regular trading on the relevant exchange or trading system); provided that if the Closing Sale Price of the Common Stock is not so reported, the “Closing Sale Price” shall be the average of the mid-point of the last bid and
ask prices for the Common Stock on the relevant date from each of at least three nationally recognized independent investment banking firms selected by the Company for this purpose. 

“Combination Settlement” has the meaning specified in Section 5.04(a). 

“Common Stock” means the shares of common stock, par value $0.001 per share, of the Company as they exist on the Issue Date,
subject to Section 5.12. 
 “Company” means the Person named as the “Company” in the first paragraph of this
instrument until a successor Person shall have become such pursuant to the applicable provisions of the Indenture, and thereafter “Company” shall mean such successor Person. 

“Conversion Agent” has the meaning specified in Section 2.04. 

  
 4 

 “Conversion Date” has the meaning specified in Section 5.03(a). 

“Conversion Notice” has the meaning specified in Section 5.03(a). 

“Conversion Period” means, with respect to any conversion of a Note: 

(i) subject to clause (ii) below, if the relevant Conversion Date occurs prior to the Final Settlement Method Election Date, the 25
consecutive Trading Day period beginning on, and including, the third Trading Day immediately following the related Conversion Date; 
 (ii)
if the relevant Conversion Date occurs after the Redemption Notice Date and on or prior to the second Scheduled Trading Day immediately preceding the related Redemption Date, the 25 consecutive Trading Day period beginning on, and including, the 27th Scheduled Trading Day preceding such Redemption Date; and 
 (iii) subject to clause
(ii) above, if the relevant Conversion Date occurs on or after the Final Settlement Method Election Date, the 25 consecutive Trading Day period beginning on, and including, the 27th Scheduled Trading Day immediately preceding the Stated
Maturity Date. 
 “Conversion Price” means, in respect of each Note, as of any date $1,000 divided by the Conversion
Rate as of such date. 
 “Conversion Rate” means, initially 41.6051 shares of Common Stock per $1,000 principal amount of
Notes, subject to adjustment as set forth herein. 
 “custodian” means the Trustee, as the initial custodian with respect
to the Global Securities, or any successor entity. 
 “Daily Conversion Value” means, for each Trading Day during the
Conversion Period, one-twenty fifth (1/25th) of the product of (i) the Conversion Rate on such Trading Day and (ii) the Daily VWAP of the Common Stock on such Trading Day. 

“Daily Measurement Value” means the Specified Dollar Amount in respect of a conversion divided by 25. 

“Daily Net Share Number” means, for each Trading Day during the relevant Conversion Period, a number of shares of Common
Stock equal to: 
 (1) the difference between the Daily Conversion Value for such Trading Day and the Daily Measurement Value, divided
by 
 (2) the Daily VWAP of the Common Stock for such Trading Day. 

  
 5 

 “Daily Settlement Amount” for each $1,000 aggregate principal amount of Notes
validly surrendered for conversion, and for each Trading Day during the relevant Conversion Period, shall consist of: 
 (1) if (x) the
Daily Conversion Value for such Trading Day exceeds (y) the Daily Measurement Value, the sum of: 
 (a) a cash payment
equal to the Daily Measurement Value, and 
 (b) the Daily Net Share Number; or 

(2) if the Daily Conversion Value for such Trading Day is less than or equal to the Daily Measurement Value, a cash payment equal to the Daily
Conversion Value. 
 “Daily VWAP” of the Common Stock (or any security that is part of the Reference Property underlying
the Notes, if applicable), in respect of any Trading Day, means the per share volume-weighted average price of Common Stock (or other security) as displayed under the heading “Bloomberg VWAP” on Bloomberg Page “ELGX <equity>
AQR” (or its equivalent successor if such page is not available, or the Bloomberg Page for any security that is part of such Reference Property, if applicable) in respect of the period from the scheduled open of trading until the scheduled
close of trading of the primary trading session on such Trading Day or, if such volume-weighted average price is unavailable (or such Reference Property is not a security), the market value of one share of Common Stock (or such Reference Property)
on such Trading Day as determined in good faith by the Board of Directors in a commercially reasonable manner, using, if practicable, a volume-weighted average price method (unless such Reference Property is not a security). The Daily VWAP will be
determined without regard to after-hours trading or any other trading outside the regular trading session. 
 “Default”
means any event that is or with the passage of time or the giving of notice or both would become an Event of Default. 

“Depository” has the meaning set forth in the Original Indenture, which shall initially be The Depository Trust Company until
a successor Depository shall have become such pursuant to the applicable provisions of the Indenture, and thereafter “Depository” shall mean such successor Depository. 

“Effective Date” has the meaning specified in Section 5.02(b). 

“Event of Default” has the meaning specified in Section 7.02. 

“Ex-Dividend Date” means the first date on which the shares of the Common Stock trade on the applicable exchange or in the
applicable market, regular way, without the right to receive the issuance, dividend or distribution in question, from the Company or, if applicable, from the seller of Common Stock on such exchange or market (in the form of due bills or otherwise)
as determined by such exchange or market. 
 “Exchange Act” means the U.S. Securities Exchange Act of 1934, as amended.

 “Expiration Date” has the meaning specified in Section 5.06(e). 

  
 6 

 “Expiration Time” has the meaning specified in Section 5.06(e). 

“Final Settlement Method Election Date” means September 27, 2018. 

“Free Convertibility Date” means September 15, 2018. 

“Fundamental Change” means the occurrence of a Change in Control or a Termination of Trading. 

“Fundamental Change Expiration Time” has the meaning specified in Section 4.01(a)(i). 

“Fundamental Change Purchase Date” has the meaning specified in Section 4.01(a). 

“Fundamental Change Purchase Notice” has the meaning specified in Section 4.01(a)(i). 

“Fundamental Change Purchase Price” has the meaning specified in Section 4.01(a). 

“Fundamental Change Purchase Right Notice” has the meaning specified in Section 4.01(b). 

“GAAP” means generally accepted accounting principles set forth in the opinions and pronouncements of the Accounting
Principles Board of the American Institute of Certified Public Accountants and statements and pronouncements of the Financial Accounting Standards Board or in such other statements by such other entity as have been approved by a significant segment
of the accounting profession, in each case, as in effect in the United States from time to time. 
 “Indenture” has the
meaning specified in the first paragraph of this Supplemental Indenture. 
 “Interest” means, when used with reference to
the Notes, any interest payable under the terms of the Notes and the Additional Interest, if any. 
 “Interest Payment
Date” means each June 15 and December 15 of each year, or if any such day is not a Business Day, the immediately following Business Day, commencing with June 15, 2014. 

“Irrevocable Election” has the meaning specified in Section 5.04(a)(iii). 

“Issue Date” means December 10, 2013. 

“Make-Whole Adjustment Event” is (i) any Change in Control (determined after giving effect to any exceptions or
exclusions from such definition but without giving effect to the proviso in clause (2) of the definition thereof), (ii) any Termination of Trading and (iii) the delivery of a Redemption Notice. 

  
 7 

 “Make-Whole Adjustment Period” has the meaning specified in
Section 5.02(a). 
 “Market Disruption Event” means (i) a failure by The NASDAQ Global Select Market, or if the
Common Stock is not listed on The NASDAQ Global Select Market, the principal other U.S. national or regional securities exchange on which the Common Stock is then listed, to open for trading or (ii) the occurrence or existence for more than one
half-hour period in the aggregate on any Scheduled Trading Day for the Common Stock of any suspension or limitation imposed on trading (by reason of movements in price exceeding limits permitted by The NASDAQ Global Select Market or otherwise) in
the Common Stock or in any options contracts or future contracts relating to the Common Stock, and such suspension or limitation occurs or exists at any time before 1:00 p.m. (New York City time) on such day. 

“Maximum Conversion Rate” has the meaning specified in Section 5.02(b). 

“Merger Transaction” has the meaning specified in Section 8.02. 

“Note” or “Notes” has the meaning specified in the fourth paragraph of the Recitals of the Company. 

“open of business” means 9:00 a.m., New York City time. 

“Optional Redemption” has the meaning specified in Section 6.02. 

“Original Indenture” has the meaning specified in the first paragraph of this Supplemental Indenture. 

“Outstanding,” when used with reference to the Notes, means all the Notes that would be deemed outstanding under
Section 2.9 of the Original Indenture except that, with respect to the Notes, (i) any Notes converted pursuant to Article 5 and required to be cancelled shall cease to be Outstanding, (ii) if the Trustee or Paying Agent segregates and
holds in trust, in accordance with the Indenture, on a Fundamental Change Purchase Date, Redemption Date or Stated Maturity Date, money sufficient to pay all principal and Interest payable on that date with respect to the Notes (or portions thereof)
to be purchased by the Company, redeemed or maturing, as the case may be, and the Trustee or Paying Agent is not prohibited from paying such money to the Holders thereof on that date pursuant to the terms of the Indenture, then on and after that
date such Notes (or portions thereof) shall cease to be Outstanding, and (iii) any Notes purchased by the Company in accordance with Section 2.07 (other than Notes purchased pursuant to cash-settled swaps or other derivatives) shall cease
to be Outstanding. 
 “Paying Agent” means the “Paying Agent” (within the meaning of the Original Indenture) with
respect to the Notes, which shall initially be the Trustee. 
 “Permitted Exchange” means any of any of The New York Stock
Exchange, The NASDAQ Global Select Market or The NASDAQ Global Market (or any of their respective successors). 

  
 8 

 “Physical Securities” means permanent certificated Notes in registered form
issued in denominations of $1,000 principal amount and integral multiples thereof. 
 “Place of Payment” has the meaning
specified in Section 2.04. 
 “Record Date” means, with respect to the payment of Interest, the June 1 (whether
or not a Business Day) immediately preceding an Interest Payment Date on June 15 and December 1 (whether or not a Business Day) immediately preceding an Interest Payment Date on December 15. 

“Redemption Date” has the meaning specified in Section 6.03(a). 

“Redemption Notice” has the meaning specified in Section 6.03(a). 

“Redemption Notice Date” has the meaning specified in Section 6.03(a). 

“Redemption Period” means the period after the Redemption Notice Date and on or prior to the close of business on the second
Scheduled Trading Day preceding the related Redemption Date. 
 “Redemption Price” has the meaning specified in
Section 6.02. 
 “Reference Property” has the meaning specified in Section 5.12(a)(iv). 

“Registrar” has the meaning specified in the Original Indenture, which, with respect to the Notes, shall initially be the
Trustee. 
 “Relevant Distribution” has the meaning specified in Section 5.06(c). 

“Scheduled Trading Day” means (i) a day that is scheduled to be a Trading Day on the principal U.S. national or regional
securities exchange or market on which the Common Stock is listed for trading or (ii) if the Common Stock is not listed on any such securities exchange or market, a Business Day. 

“SEC” means the U.S. Securities and Exchange Commission (or any successor thereto). 

“Securities Act” means the U.S. Securities Act of 1933, as amended, and the rules and regulations of the Commission
promulgated thereunder. 
 “Settlement Amount” has the meaning specified in Section 5.04(a)(iv). 

“Settlement Method” means the election of the Company as set forth in this Supplemental Indenture of settling each Settlement
Amount through Cash Settlement, Stock Settlement or Combination Settlement. 
 “Share Exchange Event” has the meaning
specified in Section 5.12. 

  
 9 

 “Significant Subsidiary” means a Subsidiary that is a “significant
subsidiary” as defined in Regulation S-X under the Exchange Act. 
 “Specified Dollar Amount” means the maximum cash
amount per $1,000 principal amount of Notes to be received upon conversion as elected by the Company in the written notice regarding the Company’s chosen Settlement Method (or deemed elected pursuant to Section 5.04(a)). 

“Spin-Off” has the meaning specified in Section 5.06(c). 

“Stated Maturity Date” means December 15, 2018. 

“Stock Price” means, with respect to a Make-Whole Adjustment Event, (i) in the case of a Make-Whole Adjustment Event
described in clause (2) of the definition of Change in Control in which the Common Stock is acquired solely for cash, the price paid per share of Common Stock in the Change in Control, or (ii) in the case of any other Make-Whole Adjustment
Event, the average of the Closing Sale Prices of Common Stock over the five Trading Day period ending on the Trading Day immediately preceding (x) the date of the Redemption Notice, in the case of a Make-Whole Adjustment Event that results from
the Company’s delivery of a Redemption Notice or (y) the Effective Date of such other Make-Whole Adjustment Event not referred to in the immediately preceding clauses (i) or (ii)(x). 

“Stock Settlement” has the meaning specified in Section 5.04(a). 

“Supplemental Indenture” means this instrument, as it may from time to time be supplemented or amended by one or more
indentures supplemental hereto entered into pursuant to the applicable provisions hereof. 
 “Termination of Trading” means
the Common Stock (or other Reference Property into which the Notes are convertible) ceases to be listed or quoted on a Permitted Exchange and will not be immediately relisted or readmitted for trading on any Permitted Exchange. 

“Trading Day” means (a) except for purposes of determining Settlement Amounts pursuant to Section 5.04, a day on
which (i) The NASDAQ Global Select Market or, if the Common Stock is not listed on The NASDAQ Global Select Market, the principal other U.S. national or regional securities exchange on which the Common Stock is then listed is open for
trading, in each case, with a scheduled closing time of 4:00 p.m. (New York City time) or the then-standard closing time for regular trading on the relevant exchange or market, and (ii) a Closing Sale Price for the Common Stock is
available on such securities exchange or market, or (b) for purposes of determining Settlement Amounts pursuant to Section 5.04 only, a day on which (i) there is no Market Disruption Event and (ii) The NASDAQ Global Select Market
or, if the Common Stock is not listed on The NASDAQ Global Select Market, the principal other U.S. national or regional securities exchange on which the Common Stock is then listed is open for trading, in either case, with a scheduled closing time
of 4:00 p.m. (New York City time) or the then-standard closing time for regular trading on the relevant exchange or market. For the purposes of both (a) and (b) of this definition, if the Common Stock is not so listed, “Trading
Day” means a Business Day. 

  
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 “Trading Price” of the Notes means, on any date of determination, subject to
Section 5.01(a)(ii), the average of the secondary market bid quotations per $1,000 principal amount of Notes obtained by the Bid Solicitation Agent for $2,000,000 principal amount of the Notes at approximately 3:30 p.m. (New York City
time) on such determination date from three independent nationally recognized securities dealers the Company selects; provided that if at least three such bids cannot reasonably be obtained, but two such bids can reasonably be obtained, then
the average of these two bids shall be used; provided further that, if at least two such bids cannot reasonably be obtained, but one such bid can reasonably be obtained, this one bid shall be used. 

“Trading Price Condition” has the meaning specified in Section 5.01(a)(ii). 

“Trigger Event” has the meaning specified in Section 5.06(c). 

“U.S.” or “United States” means the United States of America. 

“Valuation Period” has the meaning specified in Section 5.06(c). 

Section 1.03. Section References. References to Articles, Sections, Exhibits, Annexes and Schedules are to Articles, Sections,
Exhibits, Annexes and Schedules of this Supplemental Indenture unless otherwise specified. 
 ARTICLE 2 

THE NOTES 

Section 2.01. Designation, Amount and Issuance of Notes. The Notes shall be designated as “2.25% Convertible Senior Notes due
2018.” The Notes will be initially limited to an aggregate principal amount of $86,250,000, subject to Section 2.08 of this Supplemental Indenture and except for Notes authenticated and delivered upon registration or transfer of, or in
exchange for, or in lieu of, other Notes pursuant to Sections 2.7, 2.8, 2.11 and 2.14 of the Original Indenture and Sections 2.06, 4.01, 5.03 and 6.04 of this Supplemental Indenture. 

Section 2.02. Form of the Notes. The Notes and the Trustee’s certificate of authentication to be borne by such Notes shall be
substantially in the form set forth in Exhibit A hereto. The terms and provisions contained in the form of Notes attached as Exhibit A hereto shall constitute, and are hereby expressly made, a part of this Supplemental Indenture and, to the extent
applicable, the Company and the Trustee, by their execution and delivery of this Supplemental Indenture, expressly agree to such terms and provisions and to be bound thereby. 

So long as the Notes are eligible for book-entry settlement with the Depository, or unless otherwise required by law, subject to
Section 2.06 of this Supplemental Indenture, all of the Notes will be represented by one or more Global Securities. The transfer and exchange of 

  
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beneficial interests in any such Global Securities shall be effected through the Depository in accordance with the Indenture and the applicable procedures of the Depository. Except as provided in
Section 2.06 of this Supplemental Indenture, beneficial owners of a Global Security shall not be entitled to have certificates registered in their names, will not receive or be entitled to receive physical delivery of certificates in definitive
form and will not be considered Holders of such Global Security. 
 Any Global Security shall represent such of the Outstanding Notes as
shall be specified therein and shall provide that it shall represent the aggregate amount of Outstanding Notes from time to time endorsed thereon and that the aggregate amount of Outstanding Notes represented thereby may from time to time be
increased or reduced to reflect issuances, repurchases, redemptions, conversions, transfers or exchanges permitted hereby. Any endorsement of a Global Security to reflect the amount of any increase or decrease in the amount of Outstanding Notes
represented thereby shall be made by the Trustee or the custodian for the Global Security, at the direction of the Trustee, in such manner and upon instructions given by the Holder of such Notes in accordance with the Indenture. 

Section 2.03. Date and Denomination of Notes; Payment at the Stated Maturity Date; Payment of Interest. The Notes shall be
issuable in registered form without coupons in denominations of $1,000 principal amount and integral multiples thereof. Each Note shall be dated the date of its authentication and shall accrue Interest from the date specified on the face of the form
of Notes attached as Exhibit A hereto or from the most recent date to which Interest has been duly paid or provided for. 
 On the Stated
Maturity Date, each Holder shall be entitled to receive the principal amount of the Notes held. Payments in respect of the principal and interest on Global Securities representing the Notes registered in the name of the Depository or its nominee
shall be payable to the Depository or its nominee, as the case may be, in its capacity as the registered holder under the Indenture. In the case of certificated notes, payments will be made in U.S. dollars at the office of the Trustee or, at the
Company’s option, by check mailed to the Holder’s registered address (or, if requested by a Holder of more than $2,000,000 principal amount of Notes, by wire transfer to the account designated by such Holder). The Company shall make any
required interest payments to the Person in whose name each Note is registered at the close of business on the Record Date for the interest payment. 

Section 2.04. Registrar, Paying Agent and Conversion Agent. The Company agrees that the office or agency maintained by the Company
pursuant to Sections 2.4 of the Original Indenture, with respect to the Notes, shall be located in the continental United States. The Company shall also maintain an office in the continental United States where the Notes may be presented for
conversion (the “Conversion Agent”). The Company initially appoints the Trustee as the Conversion Agent and initially designates the office or agency maintained by the Company in New York City pursuant to Section 2.4 of the
Original Indenture as the place of payment for the Notes (the “Place of Payment”). 

  
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 The Company shall enter into an appropriate agency agreement with any Conversion Agent not a
party to this Supplemental Indenture. The agreement shall implement the provisions of this Supplemental Indenture that relate to such agent. The Company shall notify the Trustee of the name and address of any such agent. If the Company fails to
maintain a Conversion Agent, the Company shall act as Conversion Agent. 
 In addition to Section 2.4 of the Original Indenture, the
Company may remove any Conversion Agent upon 30 days’ prior written notice to such Conversion Agent and to the Trustee; provided that no such removal shall become effective until (1) acceptance of an appointment by a successor as
evidenced by an appropriate agreement entered into by the Company and such successor Conversion Agent and delivered to the Trustee or (2) notification to the Trustee that the Company shall serve as Conversion Agent until the appointment of a
successor in accordance with clause (1) above. The Conversion Agent may resign at any time upon written notice; provided that the Trustee may resign as Conversion Agent only if the Trustee also resigns as Trustee in accordance with
Section 7.8 of the Original Indenture. If the Conversion Agent receives any cash or shares of Common Stock hereunder, the Conversion Agent agrees to hold such cash or shares in trust for the sole benefit of the relevant Holders. 

The Company may appoint additional Conversion Agents and may approve any change in the office through which any Conversion Agent acts. 

Section 2.05. Registration of Transfer and Exchange. Notwithstanding anything in Section 2.7 of the Original Indenture to the
contrary, neither the Company nor the Trustee nor any Registrar shall be required to exchange or register a transfer of (a) any Notes or portions thereof surrendered for conversion pursuant to Article 5, (b) any Notes or portions thereof
tendered for repurchase (and not withdrawn) pursuant to Section 4.01 or (c) any Notes or portions thereof surrendered for redemption pursuant to Article 6. 

The second paragraph of Section 2.7 of the Original Indenture shall not apply to the Notes, and any reference in the Original Indenture
to such provision shall be deemed to refer to this Section 2.05. 
 Section 2.06. Global Securities. The following
provisions shall apply to Global Securities in addition to those provisions in Section 2.14 of the Original Indenture that are applicable to the Notes: 

(a) As set forth in Section 2.14 of the Original Indenture, the Company will issue, and the Trustee upon receipt of a Company Order will
authenticate, Physical Securities in the name of the Depository’s participants, in accordance with the Depository’s procedures, in exchange for the Global Security if (i) the Depository notifies the Company at any time that it is
unwilling or unable to continue as Depository for the Global Securities and a successor Depository is not appointed within 90 days; or (ii) the Depository ceases to be registered as a clearing agency under the Exchange Act and a successor
Depository is not appointed within 90 days. In addition, if an Event of Default with respect to the Notes has occurred and is continuing and any beneficial owner of an interest in a Global Security requests that its beneficial interest be exchanged
for a 

  
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Physical Security, the Company will issue and the Trustee upon receipt of a Company Order will authenticate Physical Securities in the name of such beneficial owner in exchange for the
corresponding portion of such Global Security, which the Depository will distribute to such beneficial owner. 
 Notwithstanding anything to
the contrary in the Indenture or the Notes, following the occurrence and during the continuance of an Event of Default, any beneficial owner of a Global Security may directly enforce against the Company, without the consent, solicitation, proxy,
authorization or any other action of the Depository or any other Person, such beneficial owner’s right to exchange its beneficial interest in such Global Security for a Physical Security in accordance with this Section 2.06. 

Notes issued in exchange for a Global Security or any portion thereof pursuant to this Section 2.06(a) shall be issued in definitive,
fully registered form, without Interest coupons, shall have an aggregate principal amount equal to that of such Global Securities or portion thereof to be so exchanged, shall be registered in such names and be in such authorized denominations as the
Depository shall designate and shall bear any legends required under the Indenture. The form of legend set forth in Section 2.14.3 of the Original Indenture shall be deemed replaced for purposes of the Notes with the legend set forth on the
Form of Face of Security in Exhibit A hereto. 
 (b) Upon any request by the Depository or a beneficial owner in the circumstances described
in Section 2.06(a), the Company will promptly make available to the Trustee a sufficient supply of Physical Securities in definitive, fully registered form, without Interest coupons. 

(c) At such time as all interests in a Global Security have been repurchased, converted, redeemed, cancelled or exchanged for Physical
Securities, such Global Security shall, upon receipt thereof, be canceled by the Trustee in accordance with standing procedures and instructions existing between the Depository and the custodian for the Global Security. At any time prior to such
cancellation, if any interest in a Global Security is redeemed, repurchased, converted, cancelled or exchanged for Notes in certificated form, the principal amount of such Global Security shall, in accordance with the standing procedures and
instructions existing between the Depository and the custodian for the Global Security, be appropriately reduced, and an endorsement shall be made on such Global Security, by the Trustee or the custodian for the Global Security, at the direction of
the Trustee, to reflect such reduction. The Company shall promptly notify the Trustee in writing of any repurchase, redemption, conversion, cancellation or exchange effected through any Paying Agent, Registrar or Conversion Agent other than the
Trustee. 
 Section 2.07. Purchase and Cancellation. The Company may, to the extent permitted by law, and directly or indirectly
(regardless of whether such Notes are surrendered to the Company), purchase Notes in the open market or by tender offer at any price or by private agreement. Notwithstanding anything to the contrary in the Original Indenture, the Company shall cause
any Notes so purchased (other than Notes purchased pursuant to cash-settled swaps or other derivatives) to be surrendered to the Trustee for cancellation pursuant to Section 2.12 of the Original Indenture. 

  
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 Section 2.08. Additional Notes. The Company may, from time to time without the
consent of the Holders of Outstanding Notes, reopen the Indenture and issue additional Notes under the Indenture (“Additional Notes”) with the same terms (other than date of issuance and the date from which Interest will initially
accrue) as the Notes issued on the Issue Date in an unlimited amount; provided that if any such Additional Notes are not fungible for U.S. federal income tax purposes with the Notes issued on the Issue Date, such Additional Notes shall have a
separate CUSIP number. The Notes issued on the Issue Date and any Additional Notes shall be treated as a single class for all purposes under the Indenture, including waivers, amendments and offers to purchase. 

Section 2.09. Mutilated, Destroyed, Lost or Stolen Notes. With respect to the Notes, the words “or is about to become due and
payable” in the first line of the third paragraph of Section 2.8 of the Original Indenture shall be deemed to have been deleted. 

ARTICLE 3 

PARTICULAR COVENANTS OF THE COMPANY 

Section 3.01. Covenants in Original Indenture. The following covenants of the Company are made in addition to the covenants set
forth in Article IV of the Original Indenture. 
 Section 3.02. [Reserved]. 

Section 3.03. Compliance Certificate. Notwithstanding anything to the contrary in Section 4.3 of the Original Indenture, the
Company shall deliver to the Trustee (i) within 120 days after the end of each fiscal year of the Company (beginning with the fiscal year ending December 31, 2013) an Officers’ Certificate stating whether or not the signers thereof
have knowledge of any Event of Default that occurred during the previous year and whether the Company, to the officers’ knowledge, are in default in the performance or observance of any of the terms, provisions and conditions of this Indenture
and (ii) within 30 days after the occurrence thereof, written notice of any events that would constitute an Event of Default, their status and what action the Company is taking or proposing to take in respect thereof. Any notice required to be
given under this Section 3.03 shall be delivered to a Responsible Officer of the Trustee at its Corporate Trust Office. 

Section 3.04. Further Instruments and Acts. Upon request of the Trustee, the Company will execute and deliver such further
instruments and do such further acts as may be reasonably necessary or proper to carry out more effectively the purposes of the Indenture. 

  
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 ARTICLE 4 

REPURCHASE OF NOTES 

Section 4.01. Right To Require Repurchase Upon a Fundamental Change. (a) If a Fundamental Change occurs, each Holder of Notes
shall have the option to require the Company to purchase for cash all or any portion of such Holder’s Notes that is equal to $1,000, or an integral multiple of $1,000, on the day of the Company’s choosing that is not less than 20 or more
than 35 Business Days after the occurrence of such Fundamental Change, subject to extension to comply with applicable law (such day, the “Fundamental Change Purchase Date”), at a purchase price (the “Fundamental Change
Purchase Price”) equal to 100% of the principal amount of the Notes to be purchased, plus accrued and unpaid Interest to but excluding the Fundamental Change Purchase Date (unless the Fundamental Change Purchase Date is after a
Record Date and on or prior to the Interest Payment Date to which it relates, in which case Interest accrued to the Interest Payment Date shall be paid to Holders of the Notes as of the preceding Record Date, and the purchase price the Company is
required to pay to the Holder surrendering the Note for purchase shall be equal to 100% of the principal amount of such Note subject to purchase and shall not include any accrued and unpaid Interest). 

Purchases of Notes under this Section 4.01 shall be made, at the option of the Holder thereof, upon: 

(i) delivery to the Trustee (or other Paying Agent appointed by the Company) by a Holder of a duly completed notice (the
“Fundamental Change Purchase Notice”) in the form set forth on the reverse of the Note during the period between the delivery of the Fundamental Change notice and the close of business on the second Business Day immediately
preceding the Fundamental Change Purchase Date (the “Fundamental Change Expiration Time”); and 
 (ii)
delivery or book-entry transfer of the Notes to the Trustee (or other Paying Agent appointed by the Company) at any time after delivery of the Fundamental Change Purchase Notice (together with all necessary endorsements, if the Notes are Physical
Securities) at the Corporate Trust Office of the Trustee (or other Paying Agent appointed by the Company), such delivery being a condition to receipt by the Holder of the Fundamental Change Purchase Price therefor. 

The Fundamental Change Purchase Notice shall state: 

(A) if certificated, the certificate numbers of Notes to be delivered for purchase; 

(B) the portion of the principal amount of Notes to be purchased, which must be $1,000 or an integral multiple thereof; and

 (C) that the Notes are to be purchased by the Company pursuant to the applicable provisions of the Notes and the
Indenture; 

  
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 provided, however, that if the Notes are Global Securities, the Fundamental Change Purchase Notice
must comply with applicable Depository procedures. 
 The Company shall be required to purchase, pursuant to subsection (d), Notes that have
been validly surrendered and not withdrawn on the Fundamental Change Purchase Date pursuant to subsection (c) of this Section 4.01. 

The Trustee (or other Paying Agent appointed by the Company) shall promptly notify the Company of the receipt by it of any Fundamental Change
Purchase Notice or written notice of withdrawal thereof in accordance with the provisions of subsection (c) of this Section 4.01. 

Any Note that is to be purchased only in part shall be, if certificated, surrendered to the Trustee (with, if the Company or the Trustee so
requires, due endorsement by, or a written instrument of transfer in form satisfactory to the Company and the Trustee duly executed by the Holder thereof or his attorney duly authorized in writing), and the Company shall execute, and the Trustee
shall authenticate and make available for delivery to the Holder of such Note without service charge, a new Note or Notes, containing identical terms and conditions, each in an authorized denomination in aggregate principal amount equal to and in
exchange for the unpurchased portion of the principal of the Note so surrendered, or, if a Global Security, the Trustee, or the custodian at the direction of the Trustee, shall make a notation on such Global Security as to the reduction in the
principal amount represented thereby for the purchased portion of the principal of the Note. 
 (b) The Company shall give the Trustee and
each Holder a written notice of the Fundamental Change within 5 Business Days after the occurrence of such Fundamental Change (such notice, the “Fundamental Change Purchase Right Notice”) and issue a press release announcing the
occurrence of such Fundamental Change (and make the press release available on its website). Such notice shall be either by first class mail or, with respect to Global Notes, in accordance with the Depository’s notice procedures. 

The Fundamental Change Purchase Right Notice shall specify (if applicable): 

(i) the events causing the Fundamental Change; 

(ii) the effective date of the Fundamental Change and whether the Fundamental Change is a Make-Whole Adjustment Event; 

(iii) the last date on which a Holder may exercise the purchase right pursuant to this Article 4; 

(iv) the Fundamental Change Purchase Price; 

(v) the Fundamental Change Purchase Date; 

(vi) the Conversion Rate and any adjustments to the Conversion Rate, and the procedures required for exercise of the
Holder’s conversion right; 

  
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 (vii) the procedures required for exercise of the purchase option upon the
Fundamental Change, and for withdrawal of a Fundamental Change Purchase Notice; and 
 (viii) the name and address of
the Paying Agent and the Conversion Agent. 
 No failure of the Company to give the foregoing notices and no defect therein shall limit the
Holders’ repurchase rights or affect the validity of the proceedings for the repurchase of the Notes pursuant to this Section 4.01. 

(c) A Fundamental Change Purchase Notice may be withdrawn, in whole or in part, by means of a written notice of withdrawal delivered to the
Paying Agent in accordance with the Fundamental Change Purchase Right Notice at any time until the Fundamental Change Expiration Time, specifying: 

(i) the principal amount of the Notes with respect to which such notice of withdrawal is being submitted, 

(ii) if certificated Notes have been issued, the certificate numbers of the withdrawn Notes, 

(iii) the principal amount, if any, of such Note that remains subject to the original Fundamental Change Purchase Notice, which
portion must be in principal amounts of $1,000 or an integral multiple of $1,000; 
 provided, however, that if the Notes are not in
certificated form, the withdrawal notice must comply with appropriate procedures of the Depository. 
 (d) On or prior to 11:00 a.m., New
York City time, on the Fundamental Change Purchase Date, the Company shall deposit with the Trustee (or other Paying Agent appointed by the Company or if the Company is acting as its own Paying Agent, set aside, segregate and hold in trust) an
amount of money sufficient to purchase on the Fundamental Change Purchase Date all of the Notes to be repurchased on such date at the Fundamental Change Purchase Price. Subject to receipt of funds and/or Notes by the Trustee (or other Paying Agent
appointed by the Company), payment for each Note surrendered for purchase (and not withdrawn) prior to the Fundamental Change Expiration Time shall be made on the later of (x) the Fundamental Change Purchase Date with respect to such Note
(provided the Holder has satisfied the conditions to the payment of the Fundamental Change Purchase Price in this Section 4.01), and (y) the time of book-entry transfer or the delivery of such Note to the Trustee (or other Paying
Agent appointed by the Company) by the Holder thereof in the manner required by this Section 4.01 by mailing checks for the amount payable to the Holders of such Notes entitled thereto as they shall appear in the Security Register;
provided, however, that payments to the Depository shall be made by wire transfer of immediately available funds to the account of the Depository or its nominee. The Trustee (or other Paying Agent) shall, promptly after such payment
and upon written demand by the Company, return to the Company any funds in excess of the Fundamental Change Purchase Price. 

  
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 (e) If the Trustee (or other Paying Agent appointed by the Company) holds money sufficient to
purchase on the Fundamental Change Purchase Date all the Notes or portions thereof that are to be purchased as of the Business Day following the Fundamental Change Purchase Date, then on and after the Fundamental Change Purchase Date (i) such
Notes shall cease to be Outstanding and Interest, if any, shall cease to accrue on such Notes, whether or not book-entry transfer of the Notes has been made and whether or not the Notes have been delivered to the Trustee or Paying Agent and
(ii) all other rights of the Holders of such Notes shall terminate, other than (A) the right to receive the Fundamental Change Purchase Price upon delivery or transfer of the Notes, and (B) if the Fundamental Change Purchase Date
falls after a Record Date and on or prior to the related Interest Payment Date the right of the Holder on such Record Date to receive the Interest payable on such Interest Payment Date. 

(f) In connection with any offer to purchase the Notes pursuant to this Article 4, the Company shall: 

(i) comply with the provisions of Rule 13e-4, Rule 14e-1 and any other tender offer rules under the Exchange Act to the extent
any such rules are applicable; 
 (ii) file a Schedule TO or any successor or similar schedule, if required, under the
Exchange Act; and 
 (iii) otherwise comply with all applicable federal and state securities laws, 

in each case, so as to permit the rights and obligations under this Article 4 to be exercised in the time and in the manner specified herein.

 (g) Notwithstanding anything to the contrary herein, no Notes may be purchased by the Company at the option of Holders upon a Fundamental
Change if the principal amount of the Notes has been accelerated, and such acceleration has not been rescinded, on or prior to the relevant Fundamental Change Purchase Date (except in the case of an acceleration resulting from the Company’s
default in the payment of the Fundamental Change Purchase Price with respect to such Notes). 
 ARTICLE 5 

CONVERSION 

Section 5.01. Conversion Privilege and Conversion Rate. (a) Subject to the conditions and during the periods described in
subsections (a)(i), (ii), (iii) and (iv), (b), (c) and (d) below, and upon compliance with the provisions of this Article 5, a Holder shall have the right to surrender for conversion all or any portion (if the portion to be converted
is $1,000 principal amount or an integral multiple thereof) of its Note at any time until the close of business on the Business Day immediately preceding the Free Convertibility Date. On and after the Free Convertibility Date and until the close of
business on the second Scheduled Trading Day immediately prior to the Stated Maturity Date, a Holder shall have the right to surrender all or 

  
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any portion (if the portion to be converted is $1,000 principal amount or an integral multiple thereof) of its Note for conversion, regardless of whether any of the conditions described in
subsections (a)(i), (ii), (iii) and (iv), (b), (c) and (d) below have been satisfied, upon compliance with the provisions of this Article 5. 

(i) Prior to the close of business on the Business Day immediately preceding the Free Convertibility Date, a Holder may
surrender all or any portion of its Notes for conversion during any calendar quarter commencing after the quarter ending March 31, 2014 if the Closing Sale Price of the Common Stock for at least twenty (20) Trading Days (whether or not
consecutive) in the period of thirty (30) consecutive Trading Days ending on the last Trading Day of the calendar quarter immediately preceding the calendar quarter in which the conversion occurs, is more than 130% of the Conversion Price of
the Notes in effect on each applicable Trading Day. 
 (ii) If, prior to the close of business on the Business Day
immediately preceding the Free Convertibility Date, the Trading Price per $1,000 in principal amount of the Notes on each Trading Day during any five consecutive Trading Day period is less than 98% of (x) the Closing Sale Price of the Common
Stock on such Trading Day multiplied by (y) the Conversion Rate in effect on such Trading Day, a Holder may surrender its Notes for conversion at any time during the following 5 consecutive Business Days (the “Trading Price
Condition”). 
 The Bid Solicitation Agent shall have no obligation to solicit market bid quotations unless the
Company has requested such determination in writing, and the Company shall have no obligation to make such request unless a Holder provides the Company and the Trustee with reasonable evidence that the Trading Price per $1,000 principal amount of
the Notes on any Trading Day would be less than 98% of the product of the then-current Conversion Rate multiplied by the Closing Sale Price of the Common Stock on that date. At such time, the Company shall instruct the Bid Solicitation Agent
to solicit market bid quotations for the Notes from three independent nationally recognized securities dealers that the Company selects. The Company shall determine the Trading Price per $1,000 principal amount of the Notes based upon the market bid
quotations received from the Bid Solicitation Agent beginning on such Trading Day and on each successive Trading Day until the Trading Price per $1,000 principal amount of the Notes is greater than or equal to 98% of the product of the Closing Sale
Price of the Common Stock and the Conversion Rate. 
 If on any date of determination of the Trading Price (i) the Bid
Solicitation Agent cannot reasonably obtain at least one bid for $2,000,000 principal amount of Notes from an independent nationally recognized securities dealer, (ii) if the Company has failed to request the Bid Solicitation Agent to obtain
bids when required or (iii) if the Company requested the Bid Solicitation Agent to obtain bids and the Bid Solicitation Agent has failed to obtain such bids, then, in each case, the Notes shall be convertible under the Trading Price Condition
for the next 5 consecutive Business Days following such date of determination. 

  
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 The Company shall determine the Trading Price of the Notes and whether the
Trading Price Condition has been met, and, if so, the Company shall so notify the Holders, the Trustee and the Bid Solicitation Agent. If, at any time after the Trading Price Condition has been met, the Trading Price per $1,000 principal amount of
the Notes is greater than or equal to 98% of the product of the Closing Sale Price of the Common Stock and the applicable Conversion Rate for such date, the Company shall so notify the Holders, the Trustee and the Bid Solicitation Agent. 

(iii) If the Company calls all or a portion of the Notes for redemption pursuant to Article 6, Holders may convert their Notes
that have been called for redemption at any time after the Redemption Notice Date and prior to the close of business on the second Scheduled Trading Day prior to the Redemption Date, even if such Notes are not otherwise convertible at such time.
After such second Scheduled Trading Day, the Holder’s right to convert shall expire unless the Company defaults in the payment of the Redemption Price. Notwithstanding the foregoing, if the Company calls only less than all Outstanding Notes for
redemption and a Holder (or a beneficial owner of a beneficial interest in a Global Security) is not able to determine, prior to the close of business on the 29th Scheduled Trading Day immediately preceding the relevant Redemption Date, whether the
Notes owned by such Holder (or beneficially owned by such beneficial owner) are subject to redemption (and they are convertible in accordance with the first sentence of this clause (iii)) for any reason, then such Holder (or such beneficial owner)
shall be entitled to convert such Notes after the Redemption Notice Date until the second Scheduled Trading Day immediately preceding the Redemption Date, regardless of whether such Notes (or beneficial interest) are subject to redemption. 

(iv) The Notes shall be convertible prior to the close of business on the Business Day immediately preceding the Free
Convertibility Date under the circumstances and during the periods set forth in subsections (b), (c) and (d) of this Section 5.01. 

(b) If, prior to the close of business on the Business Day immediately preceding the Free Convertibility Date, the Company elects to issue or
distribute, as the case may be, to all or substantially all holders of Common Stock: 
 (i) rights, options or warrants
entitling them to subscribe for or purchase, for a period expiring within 45 days from the announcement date for such distribution, Common Stock at a price per share that is less than the average of the Closing Sale Prices of Common Stock for the 10
consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the announcement date for such issuance; or 

(ii) cash, debt securities (or other evidence of indebtedness) or other assets or securities (including, for the avoidance of
doubt, any rights, options or warrants that are not described in clause (i) above, but excluding dividends or distributions described in Section 5.06(a)), which distribution has a per share value exceeding 10% of the Closing Sale Price of
Common Stock as of the Trading Day immediately preceding the declaration date for such distribution, 

  
 21 

 then, in either case, the Company shall notify Holders either (x) at least 35 Scheduled Trading Days
prior to the Ex-Dividend Date for such distribution or (y) at least 10 Scheduled Trading Days prior to the Ex-Dividend Date for such distribution; provided that, if the Company provides such notice in accordance with this clause
(y) but not in accordance with the immediately preceding clause (x), notwithstanding anything to the contrary in Section 5.04 or any other provision of this Indenture, the Company shall be required to settle all conversions of Notes with a
Conversion Date occurring during the period from, and including, the date of such notice to, and including, the Ex-Dividend Date for such distribution using Stock Settlement and the Company shall so notify the Holders in such notice. Once the
Company has given such notice, Holders may surrender their Notes for conversion at any time until the earlier of the close of business on the Business Day immediately preceding the Ex-Dividend Date and the Company’s announcement that such
issuance or distribution will not take place. A Holder may not convert any of its Notes under this subsection (b) if the Company provides that Holders of the Notes shall participate, at the same time and upon the same terms as holders of Common
Stock and as a result of holding the Notes, in the relevant distribution described above without having to convert their Notes as if they held a number of shares of Common Stock equal to the Conversion Rate on the record date for the distribution
multiplied by the principal amount (expressed in thousands) of Notes held by such Holder. 
 (c) If a transaction or event that constitutes
a Fundamental Change or a Make-Whole Adjustment Event occurs prior to the close of business on the Business Day immediately preceding the Free Convertibility Date, a Holder may surrender its Notes for conversion at any time from and after the date
that is the later of the date 35 Scheduled Trading Days prior to the anticipated effective date of such transaction or event and the Business Day after the Company gives notice of the transaction or event, in either case, until the close of business
on the Business Day immediately preceding the related Fundamental Change Purchase Date or, if there is no such Fundamental Change Purchase Date, the 30th Scheduled Trading Day immediately following the effective date of such transaction or event.
The Company shall use commercially reasonable efforts to give notice to Holders of the anticipated effective date for such transaction or event at least 35 Scheduled Trading Days prior to the anticipated effective date or, if the Company does not
have knowledge of such transaction or event at least 35 Scheduled Trading Days prior to the anticipated effective date, within one Business Day of the date upon which the Company receives written notice, or otherwise becomes aware, of such
transaction or event (but in no event later than the fifth Business Day following the actual effective date of such transaction or event); provided that, notwithstanding the foregoing, in no event shall the Company be required to provide such
notice to the Holders before the earlier of (i) such fifth Business Day and (ii) the earlier of such time as the Company or its affiliates (x) have publicly disclosed or acknowledged the circumstances giving rise to such transaction
or event and (y) are required to publicly disclose under applicable law or the rules of any securities exchange on which the Common Stock is then listed or admitted for trading the circumstances giving rise to such transaction or event. 

  
 22 

 (d) If the Company is a party to a consolidation, merger or binding share exchange or a sale,
assignment, conveyance, transfer, lease or other disposition of all or substantially all of its property and assets that does not also constitute a Fundamental Change or a Make-Whole Adjustment Event, in each case pursuant to which the Common Stock
would be converted into cash, securities or other property, a Holder shall have the right to surrender its Notes for conversion at any time from and including the later of the date that is the
35th Scheduled Trading Day prior to the anticipated effective date of such transaction, and the Business Day after the Company gives written notice of the transaction, in either case, to and
including the 30th Scheduled Trading Day following the effective date of such transaction. The Company shall use commercially reasonable efforts to notify Holders at least 35 Scheduled Trading Days prior to the anticipated effective date or, if the
Company does not have knowledge of such transaction, at least 35 Scheduled Trading Days prior to the anticipated effective date, within one Business Day of the date upon which the Company receives written notice, or otherwise becomes aware, of such
transaction (but in no event later than the fifth Business Day following the actual effective date of such transaction); provided that, notwithstanding the foregoing, in no event will the Company be required to provide such notice to the
Holders before the earlier of (i) such fifth Business Day and (ii) the earlier of such time as the Company or its affiliates (x) have publicly disclosed or acknowledged the circumstances giving rise to such transaction and
(y) are required to publicly disclose under applicable law or the rules of any securities exchange on which the Common Stock is then listed or admitted for trading the circumstances giving rise to such transaction. 

Section 5.02. Conversion Rate Adjustment Upon Certain Make-Whole Adjustment Events. (a) If a Holder elects to convert its
Notes during a Make-Whole Adjustment Period, the Conversion Rate shall be increased by an additional number of shares of Common Stock (the “Additional Shares”) determined pursuant to subsection (b) below. The Company shall
notify Holders, the Trustee and the Conversion Agent of the anticipated Effective Date of such Make-Whole Adjustment Event and issue a press release as promptly as commercially reasonably practicable after the Company first determines the
anticipated Effective Date of such Make-Whole Adjustment Event (and make the press release available on its website). The Company shall use its commercially reasonable efforts to give written notice to Holders of the anticipated Effective Date for a
Make-Whole Adjustment Event not more than 70 Scheduled Trading Days nor less than 35 Scheduled Trading Days prior to the anticipated Effective Date (but in no event later than the fifth Business Day following the actual effective date of such
event); provided that, notwithstanding the foregoing, in no event shall the Company be required to provide such written notice to the Holders before (i) the earlier of such fifth Business Day and (ii) the earlier of such time as the
Company or its affiliates (x) have publicly disclosed or acknowledged the circumstances giving rise to such event and (y) are required to publicly disclose under applicable law or the rules of any securities exchange on which the Common
Stock is then listed or admitted for trading the circumstances giving rise to such event. The “Make-Whole Adjustment Period” is the period (i) in the case of a Make-Whole Adjustment Event that results from the delivery of a
Redemption Notice, from, and including, the Redemption Notice Date to and including the second Scheduled Trading Day immediately preceding the Redemption Date, and (ii) in all other cases, the Effective Date of the Make-Whole Adjustment Event
to, and 

  
 23 

 
including, the Business Day immediately preceding the related Fundamental Change Purchase Date, or if such Make-Whole Adjustment Event does not also constitute a Fundamental Change, the 30th
Scheduled Trading Day immediately following the Effective Date of such Make-Whole Adjustment Event. 
 (b) The number of Additional Shares,
if any, by which the Conversion Rate shall be increased for conversions in connection with a Make-Whole Adjustment Event as set forth in clause (a) above shall be determined by reference to the table attached as Schedule A hereto, based on the
date on which the Make-Whole Adjustment Event occurs or becomes effective or the Redemption Date (in the case of a Make-Whole Adjustment Event that results from a delivery of a Redemption Notice) (the “Effective Date”) and the Stock
Price. The exact Stock Price and Effective Date may not be set forth in the table attached as Schedule A hereto, in which case if the Stock Price is: 

(i) between two Stock Prices in the table or the Effective Date is between two Effective Dates in the table, the number of
Additional Shares shall be determined by a straight-line interpolation between the number of Additional Shares set forth for the higher and lower Stock Price amounts or the earlier and later Effective Dates based on a 365-day year, as applicable;

 (ii) in excess of $80.00 per share (subject to adjustment in the same manner as the Stock Prices pursuant to subsection
(c) below), no Additional Shares shall be added to the Conversion Rate; and 
 (iii) less than $18.14 per share (subject
to adjustment in the same manner as the Stock Prices pursuant to subsection (c) below), no Additional Shares shall be added to the Conversion Rate. 

Notwithstanding anything herein to the contrary, the Company shall not increase the Conversion Rate to more than 55.1267 shares of Common Stock (the
“Maximum Conversion Rate”) per $1,000 in principal amount of Notes pursuant to the events described in this Section 5.02; provided the Company shall adjust the Maximum Conversion Rate upon the occurrence of any event for
which, and in the same manner in which, it must adjust the Conversion Rate pursuant to Section 5.06. 
 (c) The Stock Prices set forth
in the first row of the table in Schedule A hereto (i.e., the column headers) and the number of Additional Shares in the table in Schedule A hereto shall be adjusted as of any date on which the Conversion Rate of the Notes is adjusted as set
forth in Section 5.06. The adjusted Stock Prices shall equal the Stock Prices applicable immediately prior to such adjustment, multiplied by a fraction, the numerator of which is the applicable Conversion Rate immediately prior to the
adjustment giving rise to the Stock Price adjustment and the denominator of which is the Conversion Rate as so adjusted. The numbers of Additional Shares within the table attached as Schedule A hereto shall each be adjusted in the same manner and at
the same time as the Conversion Rate as set forth in Section 5.06. 

  
 24 

 Section 5.03. Exercise of Conversion Privilege. (a) Before any Holder of a Note
shall be entitled to convert the same as set forth above, such Holder shall (i) in the case of a Global Security, transfer such Note to the Conversion Agent through the facilities of the Depository and comply with the applicable conversion
procedures of the Depository in effect at that time and, if required, pay funds equal to Interest payable on the next Interest Payment Date to which such Holder is not entitled as set forth in Section 5.04(d) and, if required, pay all taxes or
duties, if any, as set forth in Section 5.09 and (ii) in the case of a Physical Security, (A) complete and manually sign and deliver an irrevocable written notice to the Conversion Agent in the form set forth in Exhibit A hereto (or a
facsimile thereof) (a “Conversion Notice”) at the office of the Conversion Agent and shall state in writing therein the principal amount of Notes to be converted and the name or names (with addresses) in which such Holder wishes the
certificate or certificates for any shares of Common Stock, if any, to be delivered upon settlement of the conversion obligation to be registered, (B) surrender such Note, duly endorsed to the Company or in blank (and accompanied by appropriate
endorsement and transfer documents), at the office of the Conversion Agent, (C) if required, pay all transfer or similar taxes, if any, as set forth in Section 5.09 and (D) if required, pay funds equal to Interest payable on the next
Interest Payment Date to which such Holder is not entitled as set forth in Section 5.04(d). The Company shall pay any documentary, stamp or similar issue or transfer tax on the issuance of any shares of Common Stock upon conversion of the
Notes, unless the tax is due because the holder requests such shares to be issued in a name other than the holder’s name, in which case the holder shall pay the tax. A Note shall be deemed to have been converted on the date (the
“Conversion Date”) that the Holder has complied with the requirements set forth in this Section 5.03. 
 If the Holder
of a Note has submitted such Note for purchase upon a Fundamental Change, such Holder may only convert such Note if it withdraw its Fundamental Change Purchase Notice prior to the Fundamental Change Expiration Time, in accordance with
Section 4.01(c). 
 (b) In case any Note shall be surrendered for partial conversion, the Company shall execute and the Trustee shall,
upon receipt of an Officers’ Certificate, authenticate and deliver to or upon the written order of the Holder of the Note so surrendered, without charge to such Holder, a new Note or Notes in authorized denominations in an aggregate principal
amount equal to the unconverted portion of the surrendered Notes. 
 Section 5.04. Settlement of Conversion Obligation.
(a) Upon conversion of any Note, the Company may choose to satisfy its conversion obligation by paying or delivering, as the case may be, to converting Holders, in respect of each $1,000 principal amount of Notes being converted, either
(1) solely cash (“Cash Settlement”), (2) shares of Common Stock, together with cash, if applicable, in lieu of any fractional share of Common Stock in accordance with Section 5.05 (“Stock Settlement”)
or (3) a combination of cash and shares of Common Stock, if any, with a particular Specified Dollar Amount (“Combination Settlement”), as set forth in this Section 5.04. 

  
 25 

 (i) All conversions on or after the Final Settlement Method Election Date shall
be settled using the same Settlement Method. If the Company has not delivered to the Trustee and all Holders a written notice of its election of a Settlement Method on or prior to the Final Settlement Method Election Date, the Company shall, with
respect to any conversions on or after the Final Settlement Method Election Date, be deemed to have elected to satisfy its conversion obligation using Stock Settlement, unless the Company has previously irrevocably elected Cash Settlement or
Combination Settlement with a Specified Dollar Amount as described in Section 5.04(a)(iii). 
 (ii) For all conversions
prior to the Final Settlement Method Election Date, the Company shall use the same Settlement Method for all conversions occurring on any given Conversion Date. In addition, the Company shall use the same Settlement Method for all conversions during
any Redemption Period as specified in its Redemption Notice. Except for any conversions that occur on or after the Final Settlement Method Election Date, during a Redemption Period or following any Irrevocable Election as described in
Section 5.04(a)(iii), the Company shall not have any obligation to use the same Settlement Method with respect to conversions that occur on different Conversion Dates, unless the Company has made the Irrevocable Election pursuant to
Section 5.04(a)(iii). If the Company elects a particular Settlement Method in connection with any conversion prior to the Final Settlement Method Election Date, unless the Company has previously made an Irrevocable Election pursuant to
Section 5.04(a)(iii) or the Conversion Date occurs during a Redemption Period, the Company shall inform Holders so converting through the Trustee of the Settlement Method the Company has selected (including the Specified Dollar Amount, if
applicable), no later than the close of business on the second Trading Day immediately following the related Conversion Date. If the Company does not timely make such an election, or if the Company does not timely elect a Settlement Method or
Specified Dollar Amount (if applicable) for conversions during any Redemption Period, the Company shall be deemed to have elected Stock Settlement. If the Company elects Combination Settlement in respect of its conversion obligation, but the Company
does not timely notify converting Holders of the Specified Dollar Amount per $1,000 principal amount of Notes, such Specified Dollar Amount shall be deemed to be equal to $1,000. In addition, and notwithstanding the foregoing, the Company shall be
required to elect Stock Settlement in the circumstances described in Section 5.01(b). 
 (iii) Prior to the Final
Settlement Method Election Date, the Company may, by written notice to Holders, at its option irrevocably elect Stock Settlement, Cash Settlement or Combination Settlement with a particular Specified Dollar Amount, for all conversions with a
Conversion Date subsequent to the Company’s delivery of such notice (any such election, an “Irrevocable Election”). 

(iv) The amount of cash, if any, and the number of shares of Common Stock, if any, that the Company is required to pay or
deliver, as the case may be, in respect of any conversion of Notes (the “Settlement Amount”) shall be computed as follows: 

(A) if the Company elects (or is deemed to have elected) to satisfy its conversion obligation through Stock Settlement, the
Company shall deliver to the converting Holder in respect of each $1,000 principal amount of Notes being 

  
 26 

 
converted a number of shares of Common stock equal to the Conversion Rate in effect on the Conversion Date (together wish cash in lieu of fractional shares as described in Section 5.05);

 (B) if the Company elects to satisfy its conversion obligation through Cash Settlement, the Company shall pay to the
converting Holder, in respect of each $1,000 principal amount of Notes being converted, cash in an amount equal to the sum of the Daily Conversion Values for each of the 25 consecutive Trading Days during the related Conversion Period; and 

(C) if the Company elects to satisfy its conversion obligation through Combination Settlement, the Company shall deliver to
Holders, in respect of each $1,000 principal amount of Notes being converted, an amount of cash and shares of Common Stock equal to the sum of the Daily Settlement Amounts for each of the 25 consecutive Trading Days during the related Conversion
Period. 
 (v) Payment or delivery, as the case may be, of the consideration due upon conversion shall be made (A) in
the case of Stock Settlement, three Business Days after the Conversion Date, unless such Conversion Date occurs following the Record Date immediately preceding the Stated Maturity Date, in which case the Company shall make such delivery (and
payment, if applicable) on the Stated Maturity Date or (B) in the case of any other Settlement Method, three Business Days after the last Trading Day of the Conversion Period; provided, however, that, in the case of clause
(A) or (B), if prior to the Conversion Date for any converted Notes the Common Stock has been replaced by Reference Property consisting solely of cash pursuant to Section 5.12, the Company shall pay the consideration due in respect of
conversion on the tenth Business Day immediately following the related Conversion Date, and, notwithstanding anything to the contrary herein, no Conversion Period shall apply to those conversions. 

(b) Each conversion shall be deemed to have been effected immediately prior to the close of business on the relevant Conversion Date;
provided, however, that the Person in whose name any shares of Common Stock shall be issuable upon such conversion shall be treated as the Holder of record of such shares as of the close of business on the Conversion Date (in the case
of Stock Settlement) or the last Trading Day of the relevant Conversion Period (in any other case). 
 (c) Any cash amounts due upon
conversion by a Holder of Notes surrendered for conversion shall be paid by the Company to such Holder, or such Holder’s nominee or nominees. In addition, the Company shall issue, or shall cause to be issued, any shares of Common Stock due upon
conversion to such Holder, or such Holder’s nominee or nominees, certificates or a book-entry transfer through the Depository (together with any cash in lieu of fractional shares). 

(d) Upon conversion, a Holder shall not receive any additional cash payment for accrued and unpaid Interest, if any, except as set forth in
this clause (d), and the Company shall not adjust the Conversion Rate to account for accrued and unpaid Interest. Except as set forth in this subsection (d), the Company’s settlement of the conversion of a Note pursuant to this

  
 27 

 
Section 5.04 shall be deemed to satisfy its obligation to pay the principal amount of such Note and accrued and unpaid Interest thereon, if any, to, but not including, the relevant
Conversion Date. Upon conversion of a Note into a combination of cash and shares of Common Stock, accrued and unpaid Interest shall be deemed to be paid first out of the cash paid upon such conversion. Notwithstanding the foregoing, if a Note is
converted after the close of business on a Record Date, the Holder of such Note at the close of business on such Record Date shall receive the Interest payable on such Note on the corresponding Interest Payment Date notwithstanding such conversion.
A Note surrendered for conversion after the close of business on any Record Date but prior to the open of business on the immediately following Interest Payment Date must be accompanied by payment of an amount equal to the Interest that will be
payable on such Interest Payment Date on the Note so converted; provided, however, that no such payment need be made: 

(i) if the Company has specified a Fundamental Change Purchase Date that is after a Record Date and on or prior to the
corresponding Interest Payment Date; 
 (ii) if the Company has specified a Redemption Date that is after a Record Date and
on or prior to the second Scheduled Trading Day after the corresponding Interest Payment Date; 
 (iii) with respect to any
Note surrendered for conversion following the Record Date immediately preceding the Stated Maturity Date; or 
 (iv) only to
the extent of any overdue Interest, if any overdue Interest remains unpaid at the time of conversion with respect to such Note. 

(v) As a result of the foregoing, (i) the Company will pay Interest on the Stated Maturity Date on all Notes converted
after the Record Date preceding the Stated Maturity Date, and converting holders will not be required to pay equivalent interest amounts and (ii) the Company will pay interest on an Interest Payment Date on all notes converted after the
corresponding Record Date and prior to a Redemption Date, and converting holders will not be required to pay equivalent interest amounts. 

Section 5.05. Fractions of Shares. The Company shall not issue any fractional share of Common Stock upon conversion of the Notes
and shall instead pay cash in lieu of any fractional share of Common Stock otherwise issuable upon conversion based on the Daily VWAP of the Common Stock on the relevant Conversion Date (in the case of Stock Settlement) or based on the Daily VWAP on
the last Trading Day of the relevant Conversion Period (in the case of any other Settlement Method). For each Note surrendered for conversion, if the Company has elected to satisfy its conversion obligation through Combination Settlement, the full
number of shares that shall be issued upon conversion thereof shall be computed on the basis of the aggregate Daily Settlement Amounts for the applicable Conversion Period and any fractional share remaining after such computation shall be paid in
cash. In addition, if more than one Note shall be surrendered for conversion at one time by the same Holder, the number of full shares that shall be issued upon conversion thereof shall be computed on the basis of the aggregate principal amount of
the Notes (or specified portions thereof) so surrendered. 

  
 28 

 Section 5.06. Adjustment of Conversion Rate. The Conversion Rate shall be adjusted
from time to time by the Company as follows: 
 (a) If the Company issues shares of Common Stock as a dividend or distribution on all or
substantially all shares of Common Stock, or if the Company subdivides or combines the Common Stock, the Conversion Rate shall be adjusted based on the following formula: 
  

											
		 	CR = CR0 ×	 	 OS
	 		 		 	
		 	 	OS0	 		 		 	

 where, 

CR0 = the Conversion Rate in effect immediately prior to the open of business on the
Ex-Dividend Date for such dividend or distribution, or immediately prior to the open of business on the effective date of such subdivision or combination of Common Stock, as the case may be; 

CR = the Conversion Rate in effect immediately after the open of business on the Ex-Dividend Date for such dividend or distribution, or
immediately after the open of business on the effective date of such subdivision or combination of Common Stock, as the case may be; 
 OS0 = the number of shares of Common Stock outstanding immediately prior to the open of business on the Ex-Dividend Date for such dividend or distribution, or immediately prior to the open of business
on the effective date of such subdivision or combination of Common Stock, as the case may be; and 
 OS = the number of shares of Common
Stock that would be outstanding immediately after giving effect to such dividend, distribution, subdivision or combination of Common Stock, as the case may be. 

Any adjustment made under this subsection (a) shall become effective immediately after the open of business on the Ex-Dividend Date for
such dividend or distribution, or immediately after the open of business on the effective date of such subdivision or combination of Common Stock, as the case may be. If such dividend, distribution, subdivision or combination described in this
subsection (a) is declared but not so paid or made, the Conversion Rate shall be immediately readjusted, effective as of the date the Board of Directors determines not to pay such dividend or distribution or to effect such subdivision or
combination, to the Conversion Rate that would then be in effect if such dividend or distribution had not been declared or such subdivision or combination had not been announced. 

(b) If an Ex-Dividend Date occurs for a distribution to all or substantially all holders of the Common Stock of any rights, options or
warrants entitling them for a period of not more than 45 calendar days from the announcement date for such distribution to subscribe for or purchase 

  
 29 

 
shares of Common Stock, at a price per share less than the average of the Closing Sale Prices of the Common Stock for the 10 consecutive Trading Day period ending on, and including, the Trading
Day immediately preceding the announcement date for such distribution, the Conversion Rate shall be increased based on the following formula: 
  

											
		 	CR = CR0 ×	 	 OS0 + X
	 		 		 	
		 	 	OS0 + Y	 		 		 	

 where, 

CR0 = the Conversion Rate in effect immediately prior to the open of business on the
Ex-Dividend Date for such distribution; 
 CR = the Conversion Rate in effect immediately after the open of business on the Ex-Dividend Date
for such distribution; 
 OS0 = the number of shares of Common Stock outstanding
immediately prior to the open of business on the Ex-Dividend Date for such distribution; 
 X = the total number of shares of Common Stock
issuable pursuant to such rights, options or warrants; and 
 Y = the number of shares of Common Stock equal to the aggregate price payable
to exercise such rights, options or warrants divided by the average of the Closing Sale Prices of Common Stock over the 10 consecutive Trading Day period ending on the Trading Day immediately preceding the announcement date for such
distribution. 
 Any increase made under this subsection (b) shall be made successively whenever any such rights, options or warrants
are issued and shall become effective immediately after the open of business on the Ex-Dividend Date for such distribution. To the extent that shares of Common Stock are not delivered after the expiration of such rights, options or warrants, the
Conversion Rate shall be decreased, as of the date of such expiration, to the Conversion Rate that would then be in effect had the increase with respect to the issuance of such rights, options or warrants been made on the basis of delivery of only
the number of shares of Common Stock actually delivered. If such rights, options or warrants are not so distributed, the Conversion Rate shall be decreased, as of the scheduled distribution date, to the Conversion Rate that would then be in effect
if the Ex-Dividend Date for such distribution had not occurred. 
 For purposes of this subsection (b) and for purposes of
Section 5.01(b)(i), in determining whether any rights, options or warrants entitle the Holders to subscribe for or purchase shares of Common Stock at a price that is less than the average of the Closing Sale Prices of the Common Stock for each
Trading Day in the applicable 10 consecutive Trading Day period, there shall be taken into account any consideration the Company receives for such rights, options or warrants and any amount payable on exercise thereof, with the value of such
consideration if other than cash to be determined in good faith by the Board of Directors. 

  
 30 

 (c) If an Ex-Dividend Date occurs for a distribution (the “Relevant
Distribution”) of shares of Capital Stock, evidences of indebtedness of the Company or other assets or property of the Company or rights, options or warrants to acquire Capital Stock or other securities of the Company, to all or
substantially all holders of the Common Stock, excluding: 
 (i) share splits, share combinations, dividends or
distributions; 
 (ii) rights, options or warrants of the type described in Section 5.06(b); 

(iii) dividends or distributions paid exclusively in cash; and 

(iv) Spin-Offs, 
 then, in each
such case, the Conversion Rate shall be adjusted based on the following formula: 
  

											
		 	CR = CR0 ×	 	 SP0
	 		 		 	
		 	 	SP0 – FMV	 		 		 	

 where, 

CR0 = the Conversion Rate in effect immediately prior to the open of business on the
Ex-Dividend Date for such distribution; 
 CR = the Conversion Rate in effect immediately after the open of business on the Ex-Dividend Date
for such distribution; 
 SP0 = the average of the Closing Sale Prices of Common
Stock over the 10 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the Ex-Dividend Date for such distribution; and 

FMV = the fair market value (as determined in good faith by the Board of Directors) of the shares of Capital Stock, evidences of indebtedness,
assets or property or rights, options or warrants distributed with respect to each outstanding share of Common Stock as of the open of business on the Ex-Dividend Date for such distribution. 

Any increase made under the above portion of this subsection (c) shall become effective immediately after the open of business on the
Ex-Dividend Date for such distribution. No adjustment pursuant to the above formula shall result in a decrease of the Conversion Rate; provided that if such distribution is not so paid or made, the Conversion Rate shall be decreased, as of
the date the Board of Directors determines not to pay or make such distribution, to be the Conversion Rate that would then be in effect if such distribution had not been declared. Notwithstanding the foregoing, if “FMV” (as defined above)
is equal to or greater than “SP0” (as defined above), in lieu of the foregoing increase, each Holder of a Note shall receive, in respect of each $1,000 principal amount thereof, at
the same time and upon the same terms as holders of Common Stock, without having to convert its Notes, the amount and kind of the Relevant Distribution that such Holder would have received if such Holder owned a number of shares of Common Stock
equal to the Conversion Rate on the record date for the distribution. 

  
 31 

 With respect to an adjustment pursuant to this subsection (c) where there has been an
Ex-Dividend Date for a dividend or other distribution on the Common Stock of shares of Capital Stock of any class or series, or similar equity interest, of or relating to a Subsidiary or other business unit, that are, or, when issued, will be,
listed or admitted for trading on a U.S. national securities exchange (a “Spin-Off”) the Conversion Rate shall be increased based on the following formula: 
  

											
		 	CR = CR0 ×	 	 FMV + MP0
	 		 		 	
		 	 	MP0	 		 		 	

 where, 

CR0 = the Conversion Rate in effect immediately prior to the open of business on the
Ex-Dividend Date for the Spin-Off; 
 CR = the Conversion Rate in effect immediately after the open of business on the Ex-Dividend Date for
the Spin-Off; 
 FMV = the average of the Closing Sale Prices of the Capital Stock or similar equity interest distributed to holders of
Common Stock applicable to one share of Common Stock (determined by reference to the definition of Closing Sale Price set forth in Section 1.02 as if references therein to Common Stock were to such Capital Stock or similar equity interest) over
the first 10 consecutive Trading Day period commencing on, and including, the Ex-Dividend Date for the Spin-Off (such period, the “Valuation Period”); and 

MP0 = the average of the Closing Sale Prices of the Common Stock over the Valuation
Period. 
 The adjustment to the Conversion Rate under the preceding paragraph of this subsection (c) shall be determined on the last
Trading Day of the Valuation Period but shall be given effect immediately after the open of business on the Ex-Dividend Date for the Spin-Off. If the Ex-Dividend Date for the Spin-Off is less than 10 Trading Days prior to, and including, the last
Trading Day of the Conversion Period in respect of any conversion, references in the definition of “FMV” above to 10 Trading Days shall be deemed to be replaced, solely in respect of such conversion, with such lesser number of Trading Days
as have elapsed from, and including, the Ex-Dividend Date for the Spin-Off to, and including, the last Trading Day of such Conversion Period. In respect of any conversion during the Valuation Period for any Spin-Off, references in the definition of
“FMV” above to 10 Trading Days shall be deemed to be replaced with such lesser number of Trading Days as have elapsed from, and including, the Ex-Dividend Date for such Spin-Off to, and including, the relevant Conversion Date. 

  
 32 

 If any dividend or distribution that constitutes a Spin-Off is declared, but not so paid or made,
the Conversion Rate shall be decreased, as of the date the Board of Directors determines not to pay or make such dividend or distribution, to be the Conversion Rate that would then be in effect in such dividend or distribution had not been declared.

 Rights, options or warrants distributed by the Company to all or substantially all holders of Common Stock, entitling the holders thereof
to subscribe for or purchase shares of the Company’s Capital Stock, including Common Stock (either initially or under certain circumstances), which rights, options or warrants, until the occurrence of a specified event or events
(“Trigger Event”): (i) are deemed to be transferred with such shares of Common Stock; (ii) are not exercisable; and (iii) are also issued in respect of future issuances of Common Stock, shall be deemed not to have
been distributed for purposes of this subsection (c) (and no adjustment to the Conversion Rate under this subsection (c) shall be required) until the occurrence of the earliest Trigger Event, whereupon such rights, options and warrants
shall be deemed to have been distributed and an appropriate adjustment (if any is required) to the Conversion Rate shall be made under this subsection (c). Subject to Section 5.15, if any such rights, options or warrants are subject to events,
upon the occurrence of which such rights, options or warrants become exercisable to purchase different securities, evidences of indebtedness or other assets, then the date of the occurrence of any and each such event shall be deemed to be the date
of distribution and Ex-Dividend Date with respect to new rights, options or warrants with such rights (and a termination or expiration of the existing rights, options or warrants without exercise by any of the holders thereof). Subject to
Section 5.15, in the event of any distribution (or deemed distribution) of rights, options or warrants, or any Trigger Event or other event (of the type described in the preceding sentence) with respect thereto that was counted for purposes of
calculating a distribution amount for which an adjustment to the Conversion Rate under this subsection (c) was made, (1) in the case of any such rights, options or warrants that shall all have been redeemed or repurchased without exercise
by any holders thereof, the Conversion Rate shall be readjusted upon such final redemption or repurchase to give effect to such distribution or Trigger Event, as the case may be, as though it were a cash distribution, equal to the per share
redemption or repurchase price received by a holder or holders of Common Stock with respect to such rights, options or warrants (assuming such holder had retained such rights or warrants), made to all holders of Common Stock as of the date of such
redemption or repurchase, and (2) in the case of such rights, options or warrants that shall have expired or been terminated without exercise by any holders thereof, the Conversion Rate shall be readjusted as if such rights, options and
warrants had not been issued. 
 For purposes of this subsection (c) and subsections (a) and (b) of this Section 5.06,
any dividend or distribution to which this subsection (c) is applicable that also includes shares of Common Stock to which subsection (a) of this Section 5.06 applies or rights, options or warrants to subscribe for or purchase shares
of Common Stock to which subsection (b) of this Section 5.06 applies, shall be deemed instead to be (1) a dividend or distribution of the shares of Capital Stock, evidences of indebtedness or other assets or property, other than such
shares of Common Stock or such rights, options or warrants, to which this subsection (c) applies (and any Conversion Rate adjustment required by this subsection (c) with respect to such dividend or

  
 33 

 
distribution shall then be made) immediately followed by (2) a dividend or distribution of such shares of Common Stock or such rights, options or warrants (and any further Conversion Rate
adjustment required by subsections (a) and (b) of this Section 5.06 with respect to such dividend or distribution shall then be made), except (A) the Ex-Dividend Date of such dividend or distribution shall under this subsection
(c) be substituted as “the Ex-Dividend Date” within the meaning of subsection (a) and subsection (b) of this Section 5.06 and (B) any shares of Common Stock included in such dividend or distribution shall not be
deemed “outstanding immediately prior to the open of business on the Ex-Dividend Date for such dividend or distribution, or immediately prior to the open of business on the effective date of such subdivision or combination of Common Stock, as
the case may be” within the meaning of subsection (a) of this Section 5.06 or “outstanding immediately prior to the open of business on the Ex-Dividend Date for such distribution” within the meaning of subsection (b) of
this Section 5.06. 
 (d) If an Ex-Dividend Date occurs for a cash dividend or distribution to all, or substantially all, holders of
outstanding Common Stock (other than any dividend or distribution in connection with the Company’s liquidation, dissolution or winding up), the Conversion Rate will be increased based on the following formula: 

 

											
		 	CR = CR0 ×	 	 SP0
	 		 		 	
		 	 	SP0 – C	 		 		 	

 where, 

CR0 = the Conversion Rate in effect immediately prior to the open of business on the
Ex-Dividend Date for such distribution; 
 CR = the Conversion Rate in effect immediately after the open of business on the Ex-Dividend Date
for such distribution; 
 SP0 = the Closing Sale Price of Common Stock on the
Trading Day immediately preceding the Ex-Dividend Date for such distribution; and 
 C = the amount in cash per share the Company pays or
distributes to all or substantially all holders of Common Stock. 
 Any increase made under this subsection (d) shall become effective
immediately after the open of business on the Ex-Dividend Date for such dividend or distribution. No adjustment pursuant to the above formula shall result in a decrease of the Conversion Rate; provided that if any dividend or distribution
described in this subsection (d) is declared but not so paid or made, the new Conversion Rate shall be readjusted, as of the date the Board of Directors determines not to pay or make such dividend or distribution, to the Conversion Rate that
would then be in effect if such dividend or distribution had not been declared. 

  
 34 

 Notwithstanding the foregoing, if “C” (as defined above) is equal to or greater than
“SP0” (as defined above), in lieu of the foregoing increase, each Holder of a Note shall receive, for each $1,000 principal amount of Notes, at the same time and upon the same terms
as holders of shares of Common Stock, without having to convert its Notes, the amount of cash that such Holder would have received if such Holder owned a number of shares of Common Stock equal to the Conversion Rate on the record date for such cash
dividend or distribution. 
 (e) If the Company or any of its Subsidiaries makes a payment in respect of a tender or exchange offer for
Common Stock and, if the cash and value of any other consideration included in the payment per share of Common Stock exceeds the Closing Sale Price of Common Stock on the Trading Day next succeeding the last date on which tenders or exchanges may be
made pursuant to such tender or exchange offer (the “Expiration Date”), the Conversion Rate shall be increased based on the following formula: 
  

											
		 	CR = CR0 ×	 	 AC + (OS × SP)
	 		 		 	
		 	 	OS0 × SP	 		 		 	

 where, 

CR0 = the Conversion Rate in effect immediately prior to the open of business on the
Trading Day next succeeding the Expiration Date; 
 CR = the Conversion Rate in effect immediately after the open of business on the Trading
Day next succeeding the Expiration Date; 
 AC = the aggregate value of all cash and any other consideration (as determined in good faith by
the Board of Directors) paid or payable for shares purchased in such tender or exchange offer; 
 OS0 = the number of shares of Common Stock outstanding immediately prior to the time (the “Expiration Time”) such tender or exchange offer expires (prior to giving effect to such
tender offer or exchange offer); 
 OS = the number of shares of Common Stock outstanding immediately after the Expiration Time (after
giving effect to such tender offer or exchange offer); and 
 SP = the average of the Closing Sale Prices of Common Stock over the 10
consecutive Trading Day period commencing on, and including, the Trading Day next succeeding the Expiration Date (the “Averaging Period”). 

The adjustment to the Conversion Rate under this subsection (e) shall be determined at the close of business on the last Trading Day of
the Averaging Period, but shall be given effect at the open of business on the Trading Day next succeeding the Expiration Date. If the Trading Day next succeeding the Expiration Date is less than 10 Trading Days prior to, and including, the end of
the Conversion Period in respect of any conversion, references in the definition of “SP” above to 10 Trading Days shall be deemed to be replaced, solely in respect of that conversion, 

  
 35 

 
with such lesser number of Trading Days as have elapsed from, and including, the Trading Day next succeeding the Expiration Date, to and including, the last Trading Day of such Conversion Period.
In respect of any conversion during the 10 Trading Days commencing on the Trading Day next succeeding the Expiration Date, references in the definition of “SP” above to 10 Trading Days shall be deemed to be replaced with such lesser number
of Trading Days as have elapsed from, and including, the Trading Day next succeeding the Expiration Date to, but excluding, the relevant Conversion Date. No adjustment pursuant to the above formula shall result in a decrease of the Conversion Rate.
If the Company or any of its Subsidiaries is obligated to purchase Common Stock pursuant to any such tender offer or exchange offer, but the Company or any of its Subsidiaries is ultimately prevented by applicable law from effecting all or any
portion of such purchases or all or any portion of such purchases are rescinded, the Conversion Rate shall immediately be readjusted to be the Conversion Rate that would then be in effect if such tender offer or exchange offer had not been made or
had been made only in respect of the purchase of Common Stock that had been effected. 
 (f) If: (i) the Company elects to satisfy its
conversion obligation through Combination Settlement and shares of Common Stock are deliverable to settle the Daily Net Share Number for a given Trading Day within the Conversion Period applicable to Notes that a Holder has converted, (ii) the
record date, effective date or expiration date for any distribution or transaction that requires an adjustment to the Conversion Rate as described in subsections (a), (b), (c), (d) and (e) of this Section 5.06 occurs on or after the
first Trading Day of the relevant Conversion Period and on or prior to the last Trading Day of such Conversion Period, (iii) such Daily Net Share Number is calculated (x) for a Trading Day in such Conversion Period that occurs on or prior
to such record date, effective date or expiration date and (y) based on a Conversion Rate that is not adjusted as described in subsections (a), (b), (c), (d) and (e) of this Section 5.06 in respect of such distribution or
transaction, and (iv) the shares a Holder will receive in respect of such Trading Day are not entitled to participate in the relevant distribution or transaction (because such shares were not held on a related record date or otherwise), then
the Company shall adjust the number of shares that the Company will deliver to you in respect of the relevant Trading Day as the Company determines appropriate in good faith to reflect the relevant distribution or transaction. 

(g) In addition to those adjustments required by subsections (a), (b), (c), (d), (e) and (f) of this Section 5.06, and to the
extent permitted by applicable law and applicable listing rules of The NASDAQ Global Select Market and any other securities exchange on which the Company’s securities are then listed, (i) the Company in its sole discretion from time to
time may increase the Conversion Rate by any amount for a period of at least 20 Business Days so long as such increase is irrevocable during such period and the Board of Directors determines that such increase would be in the Company’s best
interest and (ii) the Company may also (but is not required to) increase the Conversion Rate to avoid or diminish any income tax to holders of Common Stock or rights to purchase Common Stock in connection with a dividend or distribution of
shares (or rights to acquire shares) of Common Stock or similar events. 

  
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 (h) If a Conversion Rate adjustment becomes effective on any Ex-Dividend Date as described above,
and a Holder that has converted its Note on or after such Ex-Dividend Date and on or prior to the related record date would be treated as the record holder of shares of Common Stock as of the related Conversion Date pursuant to Section 5.04(b)
based on an adjusted Conversion Rate for such Ex-Dividend Date, then, notwithstanding the foregoing Conversion Rate adjustment provisions and settlement provisions, the Conversion Rate adjustment relating to such Ex-Dividend Date shall not be made
for such converting Holder. Instead, such Holder shall be treated as if such Holder were the record owner of the shares of Common Stock such Holder is entitled to receive upon conversion on an unadjusted basis and participate in the related
dividend, distribution or other event giving rise to such adjustment. 
 In addition, if a Holder converts a Note, Combination Settlement is
applicable to such Note and the Daily Settlement Amount for any Trading Day during the Conversion Period applicable to such Note: (i) is calculated based on a Conversion Rate adjusted on account of any distribution or transaction described in
subsections (a), (b), (c), (d) and (e) of this Section 5.06; and (ii) includes any shares of Common Stock that entitle their holder to participate in such event; then, notwithstanding the foregoing Conversion Rate adjustment
provisions and settlement provisions, (x) such Conversion Rate adjustment shall only be made for such converting Holder for such Trading Day to the extent of the cash or other consideration (other than shares of Common Stock entitled to
participate in such event) included in the Daily Settlement Amount for such Trading Day and (y) with respect to such shares of Common Stock, such Holder shall be treated as if such Holder were the record owner of the shares of Common Stock on
an unadjusted basis and participate in the related dividend, distribution or other event giving rise to such adjustment. 
 (i)
Notwithstanding the foregoing, the Conversion Rate will not be adjusted: (i) upon the issuance of any shares of Common Stock pursuant to any present or future plan providing for the reinvestment of dividends or interest payable on the
Company’s securities and the investment of additional optional amounts in shares of Common Stock under any plan; (ii) upon the issuance of any shares of Common Stock or options or rights to purchase those shares pursuant to any present or
future employee, director or consultant benefit plan or program of or assumed by the Company or any of its Subsidiaries; (iii) upon the issuance of any shares of Common Stock pursuant to any option, warrant, right or exercisable, exchangeable
or convertible security not described in subclause (ii) and outstanding as of the date the Notes were first issued; (iv) upon the repurchase of any shares of Common Stock pursuant to an open-market share repurchase program, structured
share repurchase transaction or other buy-back transaction (including through the use of derivatives) that is not a tender offer or exchange offer of the nature described under subsection (e) of this Section 5.06; (v) solely for a
change in the par value of the Common Stock; or (vi) for accrued and unpaid interest, if any. 
 (j) Adjustments to the Conversion Rate
shall be calculated to the nearest one-ten thousandth (1/10,000) of a share. The Company shall not be required to make an adjustment in the Conversion Rate unless the adjustment would require a change of at least 1% in the Conversion Rate;
provided that the Company shall carry forward any adjustment that is less than 1% of the Conversion Rate, take such carried-forward adjustments into account in any subsequent adjustment, and make such carried forward adjustments, regardless
of whether the aggregate adjustment is less than 1%, (i) on the Conversion Date for any Notes, (ii) on each 

  
 37 

 
Trading Day of the Conversion Period in respect of any Notes, (iii) on any Fundamental Change effective date, unless such adjustment has already been made and (iv) upon the
Company’s Redemption Notice. 
 (k) For purposes of this Section 5.06, the number of shares of Common Stock at any time
outstanding shall not include shares held in the treasury of the Company but shall include shares issuable in respect of scrip certificates issued in lieu of fractions of shares of Common Stock. 

(l) Whenever any provision of the Indenture requires the Company to calculate Closing Sale Prices, Daily VWAPs, Daily Conversion Values, Daily
Settlement Amounts or the Stock Price for purposes of a Make-Whole Adjustment Event over a span of multiple days, the Board of Directors shall make appropriate adjustments to account for any adjustment to the Conversion Rate that becomes effective,
or any event requiring an adjustment to the Conversion Rate where the Ex-Dividend, Expiration Date or effective date of the event occurs, at any time during the period for which such Closing Sale Prices, Daily VWAPs, Daily Conversion Values, Daily
Settlement Amounts or the Stock Price is to be calculated. For the avoidance of doubt, the adjustments made pursuant to this subsection (l) shall be made without duplication of any adjustment made pursuant to subsetion (f) of this
Section 5.06. 
 (m) No adjustment to the Conversion Rate need be made for a given transaction if each Holder of a Note will be
entitled to participate in such transaction, without conversion of such Note, on the same terms and at the same time as the holder of a number of shares of Common Stock equal to (i) the principal amount of such Holder’s Note divided
by $1,000 and multiplied by (ii) the Conversion Rate would be entitled to participate. 
 Section 5.07. Notice of
Adjustments of Conversion Rate. Whenever the Conversion Rate is adjusted as herein provided, the Company shall compute the adjusted Conversion Rate in accordance herewith and shall prepare a certificate signed by the Chief Financial Officer or
Controller of the Company setting forth the adjusted Conversion Rate and describing in reasonable detail the facts upon which such adjustment is based. Such certificate shall promptly be filed with the Trustee and with the Conversion Agent (if other
than the Trustee), and the Company shall issue a press release containing the relevant information (and make the press release available on its website). Failure to deliver any such certificate or notice shall not affect the validity of such
adjustment. 
 Section 5.08. Company To Reserve Common Stock. The Company shall at all times and from time to time reserve and
keep available, free from preemptive rights, out of its authorized but unissued Common Stock that is not committed for any other purpose, for the purpose of issuance upon conversion of Notes, a number of shares of Common Stock equal to the product
of (a) the Maximum Conversion Rate and (b) the aggregate principal amount of Outstanding Notes divided by $1,000. 

Section 5.09. Taxes on Conversions. The Company shall pay any and all documentary, stamp or similar issue or transfer taxes that
may be payable in respect of the issuance of shares of 

  
 38 

 
Common Stock upon any conversion of Notes hereunder; provided that the Company shall not be required to pay any tax that is due because the converting Holder requests such shares to be
issued in a name other than such Holder’s name, and no such issuance shall be made unless and until the Holder has paid to the Company the amount of any such tax or duty, or has established to the satisfaction of the Company that such tax or
duty has been paid. 
 Section 5.10. Certain Covenants. Before taking any action which would cause an adjustment reducing the
Conversion Rate below the then par value, if any, of the shares of Common Stock issuable upon conversion of the Notes, the Company shall take all corporate action that it reasonably determines is necessary to ensure that the Company may validly and
legally issue a number of shares of Common Stock equal to the Maximum Conversion Rate (giving effect to such prospective adjustment), and that such shares would be considered fully paid under applicable law. 

Section 5.11. Cancellation of Converted Notes. All Notes delivered to the Conversion Agent for conversion shall be delivered to
the Trustee or its agent and canceled by the Trustee as provided in Section 2.12 of the Original Indenture. 
 Section 5.12.
Provision in Case of Effect of Reclassification, Consolidation, Merger or Sale. (a) In the event of: 
 (i) any
recapitalization, reclassification or change of the Common Stock (other than changes resulting from a subdivision or combination or a change to the par value of the Common Stock); 

(ii) a consolidation, merger, combination, binding share exchange or similar transaction involving the Company; 

(iii) a sale, assignment, conveyance, transfer, lease or other disposition to another Person of the Company’s property and
assets as an entirety or substantially as an entirety; or 
 (iv) a liquidation or dissolution of the Company, 

in each case, in which holders of outstanding Common Stock are entitled to receive cash, securities or other property for their shares of Common Stock
(“Reference Property” and any such transaction, a “Share Exchange Event”), then the Company or the successor or purchasing Person, as the case may be, shall execute with the Trustee a supplemental indenture
permitted hereby providing that, at and after the effective time of such Share Exchange Event, Holders of each $1,000 principal amount of Notes will be entitled to convert their Notes into the kind and amount of Reference Property that a holder of a
number of shares of Common Stock equal to the Conversion Rate immediately prior to such Share Exchange Event would have owned or been entitled to receive upon such Share Exchange Event; provided that at and after the effective time of any
such Share Exchange Event, (i) the Company will continue to have the right to determine the Settlement Method applicable to any conversion of Notes, unless the Company has 

  
 39 

 
previously made an Irrevocable Election pursuant to Section 5.04(a), (ii) any amount otherwise payable in cash upon conversion of the Notes pursuant to Section 5.04(a)(iv) shall
continue to be payable in cash, (iii) any shares of Common Stock that the Company would have been required to deliver upon conversion of the Notes pursuant to Section 5.04(a)(iv) shall instead be deliverable in the amount and type of
Reference Property that a holder of that number of shares of Common Stock would have received in such Share Exchange Event and (iv) the Daily VWAP shall be calculated based on the value of a unit of Reference Property that a holder of one share
of Common Stock would have received in such Share Exchange Event. Such supplemental indenture shall also provide for anti-dilution and other adjustments that are as nearly equivalent as possible to the adjustments set described in Section 5.06.
If the Reference Property in respect of any such Share Exchange Event includes shares of stock, securities or other property or assets of a company other than the successor or purchasing Person, as the case may be, in such Share Exchange Event, such
other company shall also execute such supplemental indenture, and such supplemental indenture shall contain such additional provisions to protect the interests of the Holders, including the right of Holders to require the Company to purchase their
Notes upon a Fundamental Change pursuant to Section 4.01, as the Board of Directors reasonably considers necessary by reason of the foregoing. If the Notes become convertible into Reference Property pursuant to this Section 5.12 or such a
supplemental indenture, the Company shall notify the Trustee in writing and issue a press release containing the relevant information and make such press release available on the Company’s website. Throughout Article 5, if the Common Stock has
been replaced by Reference Property as a result of any Share Exchange Event, references to Common Stock are intended to refer to such Reference Property, subject to the provisions of such supplemental indenture. 

For purposes of this Section 5.12, the type and amount of consideration that holders of Common Stock are entitled to in the case of Share
Exchange Events that cause Common Stock to be converted into the right to receive more than a single type of consideration because the holders of Common Stock have the right to elect the type of consideration they receive shall be deemed to be the
weighted average of the types and amounts of consideration received by the holders of Common Stock that affirmatively make such an election. The Company shall notify Holders of such weighted average as soon as practicable after such determination is
made. If the Holders receive only cash in any Share Exchange Event, then for all conversions that occur after the effective date of such Share Exchange Event (i) the consideration due upon conversion of each $1,000 principal amount of Notes
shall be solely cash in an amount equal to the Conversion Rate in effect on the relevant Conversion Date (as may be increased by any Additional Shares), multiplied by the price paid per share of Common Stock in such Share Exchange Event and
(ii) the Company shall satisfy its conversion obligation by paying cash to converting Holders on the tenth Business Day immediately following the relevant Conversion Date. The Company shall not become a party to any Share Exchange Event unless
its terms are consistent with this Section 5.12. 
 (b) The above provisions of this Section 5.12 shall similarly apply to
successive Share Exchange Events. 

  
 40 

 Section 5.13. Responsibility of Trustee for Conversion Provisions. The Trustee and
any Conversion Agent, subject to the provisions of Article VII of the Original Indenture, shall not at any time be under any duty or responsibility to any Holder of Notes or to the Company to determine whether any facts exist which may require any
adjustment of the Conversion Rate, or with respect to the nature or extent of any such adjustment when made, or with respect to the method employed, herein or in any supplemental indenture provided to be employed, in making the same, or whether a
supplemental indenture need be entered into. Neither the Trustee nor any Conversion Agent, subject to the provisions of Article VII of the Original Indenture, shall be responsible for any failure of the Company to make or calculate any cash payment
or to issue, transfer or deliver any shares of Common Stock or share certificates or other securities or property or cash upon the surrender of any Note for the purpose of conversion; and the Trustee and any Conversion Agent, subject to the
provisions of Article VII of the Original Indenture, shall not be responsible for any failure of the Company to comply with any of the covenants of the Company contained in this Article 5. 

Section 5.14. Notice to Holders Prior to Certain Actions. In case of: 

(a) any action by the Company or any Subsidiary thereof that would require an adjustment to the Conversion Rate under Section 5.06 or
5.15; 
 (b) any Share Exchange Event; 

(c) any voluntary or involuntary dissolution, liquidation or winding up of the Company or any of its Subsidiaries; or 

(d) any Merger Transaction; 
 then, in each case
(unless notice of such event is otherwise required pursuant to another provision of the Indenture excluding, for the avoidance of doubt, Section 5.07), the Company shall cause to be filed with the Trustee and the Conversion Agent and to be sent
to each Holder at such Holder’s address appearing on the list of Holders provided for in Section 2.6 of the Original Indenture, as promptly as practicable but in any event at least five calendar days prior to the applicable date specified
in clause (x) or (y) below (or, if later, no more than two Business Days following the date on which the Company knows of the applicable date specified in clause (x) or (y) below), a notice stating (x) the date on which a
record is to be taken for the purpose of such action by the Company or its Subsidiary or, if a record is not to be taken, the date as of which the holders of Common Stock of record are to be determined for the purposes of such action by the Company
or its Subsidiary, or (y) the date on which such Share Exchange Event, Merger Transaction, dissolution, liquidation or winding up is expected to become effective or occur, and, if applicable, the date as of which it is expected that holders of
Common Stock of record shall be entitled to exchange their Common Stock for securities or other property deliverable upon such Share Exchange Event, Merger Transaction, dissolution, liquidation or winding up. Failure to give such notice, or any
defect therein, shall not affect the operation of any provision herein consequent on such event. 

  
 41 

 Section 5.15. Stockholder Rights Plan. To the extent that the Company has a rights
plan in effect upon conversion of the Notes (i.e., a poison pill), converting Holders of the Notes shall receive, in addition to any Common Stock received in connection with such conversion, the rights under such rights plan, unless prior to
such conversion, the rights have separated from the Common Stock, in which case the Conversion Rate shall be adjusted at the time of separation as if the Company distributed to all holders of Common Stock shares of the Company’s Capital Stock,
evidences of indebtedness or other assets or property, pursuant to Section 5.06(c), subject to readjustment in the event of the expiration, termination or redemption of such rights. 

ARTICLE 6 

REDEMPTION 

Section 6.01. Original Indenture. This Article 6 supersedes Article III of the Original Indenture in its entirety, and any
reference in the Original Indenture to such Article III or any provision therein shall be deemed to refer to this Article 6 or the corresponding provision herein (if any), as the case may be. 

Section 6.02. Redemption. The Notes shall not be redeemable by the Company prior to December 15, 2016. On or after
December 15, 2016, the Company may redeem (an “Optional Redemption”) for cash all or any portion of the Notes, at the Company’s option, except for any Notes that the Company is required to purchase pursuant to Article 4,
at a redemption price equal to 100% of the principal amount of the Notes to be redeemed, plus accrued and unpaid interest, if any, to, but excluding, the Redemption Date (the “Redemption Price”) (unless the Redemption Date falls
after a Record Date but on or prior to the related Interest Payment Date, in which case the Company will instead pay the full amount of accrued and unpaid Interest to the Holder of record as of the close of business on such Record Date and the
Redemption Price shall be equal to 100% of the principal amount of the Notes to be redeemed); provided that the Notes shall only be redeemable pursuant to this Article 6 if the Closing Sale Price of the Common Stock for at least 20 Trading
Days (whether or not consecutive) during any 30 consecutive Trading Day period ending on, and including, the second Trading Day immediately preceding the date on which the Company provides a Redemption Notice, exceeds 130% of the Conversion Price on
each applicable Trading Day. 
 Section 6.03. Notice of Optional Redemption; Selection of Notes.  

(a) In case the Company exercises its Optional Redemption right to redeem all or, as the case may be, any part of the Notes pursuant to
Section 6.02, (i) the Company shall fix a date for redemption which must be a Business Day (each, a “Redemption Date”), (ii) the Company shall send a written notice of such Optional Redemption (a “Redemption
Notice”) to the Trustee and Holders of Notes not less than 30 Scheduled Trading Days nor more than 60 calendar days immediately preceding the Redemption Date (the date on which such Redemption Notice is delivered, the “Redemption
Notice Date”); and (iii) if the Company does not redeem all of the Notes, (A) the Trustee shall select the Notes or portions of Notes to be redeemed, in principal amounts of $1,000 or integral multiples of $1,000, in accordance
with applicable procedures of 

  
 42 

 
the Depository or if the Depository does not prescribe a method of selection, on a pro rata basis, by lot or in accordance with any such method as the Trustee deems fair and appropriate and
(B) the Trustee shall notify the Company promptly of the Notes or portions of Notes to be called for redemption. 
 (b) Each Redemption
Notice shall specify: 
 (i) the Redemption Date; 

(ii) the Redemption Price; 

(iii) that Holders may surrender their Notes for conversion at any time during the Redemption Period in accordance with the
procedures set forth in Article 5; 
 (iv) the Settlement Method which will apply to all conversions during the Redemption
Period; 
 (v) the Conversion Rate then in effect and, if applicable, the number of Additional Shares added to the Conversion
Rate in accordance with Section 5.02; 
 (vi) the procedures a converting Holder must follow to convert its Notes; 

(vii) that on the Redemption Date, the Redemption Price will become due and payable upon each such Note, and that Interest
thereon, if any, shall cease to accrue on and after said date; 
 (viii) the place or places where such Notes are to be
surrendered for payment of the Redemption Price; 
 (ix) the CUSIP, ISIN or other similar numbers, if any, assigned to such
Notes; and 
 (x) in case any Note is to be redeemed in part only, the portion of the principal amount thereof to be redeemed
and on and after the Redemption Date, upon surrender of such Note, a new Note in principal amount equal to the unredeemed portion thereof shall be issued. 

At the Company’s written request and expense, the Trustee shall give the Redemption Notice to each Holder of Notes to be redeemed in the Company’s
name and at the Company’s expense, provided, however, that the Company has delivered to the Trustee (i) at least 5 Business Days prior to the notice date, written notice indicating that, if the Company so elects to redeem the
Notes in accordance with the requirements set forth above, the Trustee will need to deliver a Redemption Notice to each Holder of Notes and setting forth in draft form the information the Company expects to be stated in such Redemption Notice to the
extent such information is available to the Company at such time and (ii) at least 1 Business Day prior to the notice date, an Officers’ Certificate requesting that the Trustee give such Redemption Notice and setting forth the information
to be stated in such Redemption Notice. 

  
 43 

 (c) If the Trustee selects a portion of a Holder’s Notes for partial redemption and such
Holder thereof converts a portion of such Note, the portion of the Note submitted for conversion shall be deemed to be from the portion selected for redemption. 

Section 6.04. Payment of Notes Called for Redemption.  

(a) If any Redemption Notice has been given in respect of the Notes in accordance with Section 6.03, the Notes shall become due and
payable on the Redemption Date at the Place of Payment and at the applicable Redemption Price. On presentation and surrender of the Notes at the Place of Payment, the Notes shall be paid and redeemed by the Company at the applicable Redemption
Price. In the case of any redemption in part, the Company shall execute and the Trustee shall, upon receipt of an Officers’ Certificate, authenticate and deliver to or upon the written order of the Holder of the Note so surrendered, without
charge to such Holder, a new Note or Notes in authorized denominations in an aggregate principal amount equal to the unredeemed portion of the Note so surrendered. 

(b) Prior to 11:00 a.m., New York City time, on the Redemption Date, the Company shall deposit with the Paying Agent or, if the Company is
acting as the Paying Agent, shall segregate and hold in trust an amount of cash (in immediately available funds if deposited on the Redemption Date), sufficient to pay the Redemption Price of all of the Notes to be redeemed on such Redemption Date.
Subject to receipt of funds by the Paying Agent, payment for any Note to be redeemed shall be made on the Redemption Date for such Note or, if later, at the time of presentation of such Note to the Trustee (or other Paying Agent appointed by the
Company) by the Holder thereof in the manner required by this Section 6.04. Commencing on the Redemption Date, if the Company has deposited, or has segregated and is holding in trust, such funds, the Notes to be redeemed shall cease to accrue
Interest. The Paying Agent shall, promptly following such payment and upon written demand by the Company, return to the Company any funds in excess of the Redemption Price. 

Section 6.05. Restrictions on Redemption. Notwithstanding anything to the contrary herein, the Company may not redeem any Notes if
the principal amount of the Notes has been accelerated in accordance with the terms of this Indenture, and such acceleration has not been rescinded, on or prior to the Redemption Date. 

Section 6.06. No Sinking Fund. No sinking fund is provided for the Notes, and Article XI of the Original Indenture is inapplicable
with respect to the Notes. 

  
 44 

 ARTICLE 7 

EVENTS OF DEFAULT; REMEDIES 

Section 7.01. Original Indenture. With respect to the Notes, (i) Section 7.02 hereof shall supersede Section 6.1 of
the Original Indenture; (ii) Section 7.03 hereof shall supersede Section 6.2 of the Original Indenture; (iii) Section 7.04 hereof shall supersede Section 6.7 of the Original Indenture; (iv) Section 7.05 hereof
shall supersede Section 6.8 of the Original Indenture; (v) Section 7.06 hereof shall supersede Section 6.13 of the Original Indenture; (vi) Section 7.07 hereof shall supersede Section 6.14 of the Original Indenture, and any
reference in the Original Indenture to any such provision of the Original Indenture shall be deemed to refer to the corresponding provision herein (if any). 

Additionally, Section 7.2(f) of the Original Indenture shall hereby be deemed amended by deleting the phrase “reasonable security or
indemnity” and replacing it with the phrase “indemnity or security satisfactory to it”. 
 Section 7.02. Events of
Default. 
 Notwithstanding the “Events of Default” set forth in Section 6.1 of the Original Indenture, which shall not
apply with respect to the Notes, each of the following events shall constitute an “Event of Default” hereunder: 
 (a)
failure by the Company to pay the principal of any Note when due; 
 (b) failure by the Company to pay or deliver, as the case may be, the
Settlement Amount owing upon conversion of any Note (including any Additional Shares or cash in lieu thereof) within 5 calendar days; 
 (c)
failure by the Company to pay any Interest on any Note when due, and such failure continues for 30 days; 
 (d) failure by the Company
to pay the Fundamental Change Purchase Price or the Redemption Price of any Note when due; 
 (e) failure by the Company to provide timely
written notice of a transaction or event, the occurrence (or delivery by the Company of notice) of which would give rise to a right of Holders to convert their Notes pursuant to Section 5.01(b) or (d), or a Fundamental Change or a Make-Whole
Adjustment Event, in accordance with the terms provided in Section 4.01(b), 5.01(b), 5.01(d) or 5.02, as the case may be; 
 (f)
failure by the Company to perform any other covenant required of it as provided in the Indenture (other than a covenant or agreement a default in whose performance or whose breach is specifically dealt with in subsections (a) through
(e) above) and such failure continues for 60 days after written notice thereof has been received by the Company from the Trustee or the Holders of at least 25% in aggregate principal amount of the Notes then Outstanding; 

  
 45 

 (g) any indebtedness for money borrowed by, or any other payment obligation of, the Company or
any of its Subsidiaries that is a Significant Subsidiary (or any group of Subsidiaries that, taken together, would constitute a Significant Subsidiary), in an outstanding principal amount, individually or in the aggregate, in excess of
$15 million is not paid at final maturity (or when otherwise due) or is accelerated, unless such indebtedness is discharged or such acceleration is cured, waived, rescinded, stayed or annulled within a period of 30 days after becoming due and
payable; 
 (h) failure by the Company or any of its Subsidiaries that is a Significant Subsidiary (or any group of Subsidiaries that, taken
together, would constitute a Significant Subsidiary) to pay one or more final and non-appealable judgments entered by a court or courts of competent jurisdiction, the aggregate uninsured or unbonded portion of which is in excess of $15 million,
if the judgments are not paid, discharged or stayed within 30 days; and 
 (i) the Company or any Significant Subsidiary (or any group
of Subsidiaries that, taken together, would constitute a Significant Subsidiary) thereof shall commence a voluntary case or other proceeding seeking liquidation, reorganization or other relief with respect to the Company or any such Significant
Subsidiary or its debts under any bankruptcy, insolvency or other similar law now or hereafter in effect or seeking the appointment of a trustee, receiver, liquidator, custodian or other similar official of the Company or any such Significant
Subsidiary or any substantial part of its property, or shall consent to any such relief or to the appointment of or taking possession by any such official in an involuntary case or other proceeding commenced against it, or shall make a general
assignment for the benefit of creditors, or shall fail generally to pay its debts as they become due; or 
 (j) an involuntary case or other
proceeding shall be commenced against the Company or any Significant Subsidiary (or any group of Subsidiaries that, taken together, would constitute a Significant Subsidiary) thereof seeking liquidation, reorganization or other relief with respect
to the Company or such Significant Subsidiary or its debts under any bankruptcy, insolvency or other similar law now or hereafter in effect or seeking the appointment of a trustee, receiver, liquidator, custodian or other similar official of the
Company or such Significant Subsidiary or any substantial part of its property, and such involuntary case or other proceeding shall remain undismissed and unstayed for a period of 90 consecutive days. 

Section 7.03. Acceleration of Maturity; Rescission and Annulment. If an Event of Default, other than an Event of Default specified
in Section 7.02(i) or Section 7.02(j) with respect to the Company, occurs and is continuing, then in every such case either the Trustee or the Holders of at least 25% in aggregate principal amount of the Outstanding Notes may declare the
principal amount of, and all accrued unpaid Interest on, the Notes to be due and payable immediately, by a notice in writing to the Company (with a copy to the Trustee), and upon any such declaration such principal and Interest shall become
immediately due and payable. If an Event of Default specified in Section 7.02(i) or Section 7.02(j) occurs with respect to the Company, the principal amount of, and accrued and unpaid Interest, if any, on, all of the Notes shall become
immediately due and payable without any declaration or other act of the Holders or any act on the part of the Trustee. 

  
 46 

 At any time after such an acceleration but before a judgment or decree based on such
acceleration, the Holders of a majority in aggregate principal amount of the Outstanding Notes, by written notice to the Company and the Trustee, may rescind and annul such acceleration (other than with respect to an Event of Default under Sections
7.02(a) (including the Fundamental Change Purchase Price and the Redemption Price)) if: 
 (i) such rescission and annulment
will not conflict with any judgment or decree of a court of competent jurisdiction; 
 (ii) all Events of Default, other than
the non-payment of the principal amount on Notes that have become due solely by such acceleration, have been cured or waived as provided in Section 7.06; and 

(iii) all amounts owing to the Trustee have been paid. 

No such rescission shall affect any subsequent default or impair any right consequent thereon. 

Notwithstanding the foregoing and notwithstanding the remedies afforded to Holders upon the occurrence and during the continuation of an Event
of Default as set forth in Article VI of the Original Indenture, at the election of the Company, the sole remedy for an Event of Default relating to (i) the failure by the Company to file with the Trustee pursuant to Section 314(a)(1) of
the Trust Indenture Act any documents or reports that the Company is required to file with the SEC pursuant to Section 13 or 15(d) of the Exchange Act or (ii) the failure by the Company to comply with its reporting obligations to the
Trustee and the SEC, under Section 9.01 hereof, shall, for the 180 days after the occurrence of such an Event of Default, consist exclusively of the right to receive additional interest on the Notes (“Additional Interest”) at
an annual rate equal to (x) for the first 90 days after the occurrence of such an Event of Default, 0.25% of the aggregate principal amount of the Notes to, but not including, the 91st day
thereafter, and (y) for the 90 days from, and including, the 91st day after the occurrence of such an Event of Default, 0.50% of the aggregate principal amount of the Notes to, but not
including, the 181st day after the occurrence of such an Event of Default (or, in each case of clauses (x) and (y), if applicable, the earlier date on which the Event of Default relating to the reporting obligations is cured or waived). Any
such Additional Interest shall be payable in the same manner and on the same dates as the stated Interest payable on the Notes. If such Event of Default is continuing on the 181st day after such Event of Default first occurred, the Notes shall be
subject to acceleration in accordance with the provisions of this Section 7.03 as provided above. This paragraph and the two immediately succeeding paragraphs shall not affect the rights of Holders of Notes in the event of the occurrence of any
other Event of Default. In the event the Company does not elect to pay the Additional Interest upon an Event of Default in accordance with this paragraph, the Notes shall be subject to acceleration in accordance with the first paragraph of this
Section 7.03. 
 In order to elect to pay Additional Interest as the sole remedy during the first 180 days after the occurrence of an
Event of Default relating to the failure to comply with the reporting 

  
 47 

 
obligations set forth in Section 9.01 in accordance with the immediately preceding paragraph, the Company must notify in writing all Holders of record of Notes and the Trustee and Paying
Agent of such election on or before the close of business on the fifth Business Day prior to the date on which such Event of Default would otherwise occur. Upon the Company’s failure to timely give such notice or pay Additional Interest, the
Notes shall be immediately subject to acceleration in accordance with the first paragraph of this Section 7.03. In no event shall Additional Interest accrue at a rate per year in excess of 0.25% (during the period described in clause
(x) of the immediately preceding paragraph) or 0.50% (during the period described in clause (y) of the immediately preceding paragraph), as applicable, pursuant to this Indenture, regardless of the number of events or circumstances giving
rise to requirements to pay such Additional Interest pursuant to the immediately preceding paragraph. With regard to any violation specified in the immediately preceding paragraph, no Additional Interest shall accrue, and no right to declare the
principal or other amounts due and payable in respect of the Notes shall exist, after such violation has been cured. 
 If Additional
Interest is payable under this Section 7.03, the Company shall deliver to a Responsible Officer of the Trustee at the Corporate Trust Office a certificate to that effect stating that Additional Interest is payable and the date upon which such
Additional Interest shall begin to accrue. Unless and until a Responsible Officer of the Trustee receives at the Corporate Trust Office such a certificate, the Trustee may assume without inquiry that Additional Interest is not payable. If Additional
Interest has been paid by the Company directly to the persons entitled to it, the Company shall deliver to the Trustee a certificate setting forth the particulars of such payment. 

Payments of the Redemption Price, the Fundamental Change Purchase Price, principal and Interest that are not made when due shall accrue
Interest per annum at the then-applicable interest rate from the required payment date. 
 Section 7.04. Limitation on Suits.
Notwithstanding Section 6.7 of the Original Indenture, which shall not apply to the Notes, no Holder of any Note shall have any right to institute any proceeding, judicial or otherwise, with respect to this Indenture, or for the appointment
of a receiver or trustee, or for any other remedy hereunder, unless: (i) such Holder has previously given written notice to the Trustee of a continuing Event of Default; (ii) the Holders of at least 25% in aggregate principal amount of the
Notes then outstanding have made a written request and have offered indemnity or security to the Trustee satisfactory to it to institute such proceeding as Trustee; and (iii) the Trustee has failed to institute such proceeding within 60 days
after such notice, request and offer and has not received from the Holders of a majority in aggregate principal amount of the Notes then outstanding a direction inconsistent with such request within 60 days after such notice, request and offer.
However, the limitation on the right of Holders to institute a proceeding under this Section 7.04 shall not apply to a suit instituted by a Holder for the enforcement of payment of the principal of or interest on any Note on or after the
applicable due date, the right to convert the Note or to receive the consideration due upon conversion or the right of a beneficial owner to exchange its beneficial interest in a Global Security representing Notes for a Physical Security if an Event
of Default has occurred and is continuing, in each case, in accordance with applicable provisions of this Indenture. 

  
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 Section 7.05. Unconditional Right of Holders To Receive Payment. Notwithstanding any
other provision of the Indenture or the Notes, any Holder has the right to receive payment or delivery, as the case may be, of the principal amount, the Redemption Price, Fundamental Change Purchase Price or accrued and unpaid Interest, if any, in
respect of the Notes held by such Holder, on or after the respective due dates expressed in the Notes or any Fundamental Change Purchase Date, as applicable, and the consideration due upon conversion of the Notes in accordance with Article 5, or to
institute suit for the enforcement of any such payment on or after such respective dates or the right to convert, and such right to receive such payment or delivery, as the case may be, shall not be impaired or affected adversely without the consent
of such Holder. 
 Section 7.06. Waiver of Defaults and Events of Default. Notwithstanding Section 6.13 of the Original
Indenture, subject to Section 11.02, the Holders of not less than a majority of the aggregate principal amount of the Outstanding Notes may on behalf of the Holders of all of the Notes waive any Default or Event of Default hereunder, unless:

 (i) the Company fails to pay the principal of or any Interest on any Note when due; 

(ii) the Company fails to pay or deliver the consideration due upon conversion of any Note within the time period required
herein; or 
 (iii) the Company fails to comply with any of the provisions herein the modification of which would require the
consent of the Holder of each Outstanding Note affected. 
 Upon any such waiver, such Default or Event of Default shall cease to exist, and any Event of
Default arising from such Default shall be deemed to have been cured, for every purpose of the Indenture; but no such waiver shall extend to any subsequent or other Default or Event of Default or impair any right consequent thereon. 

Section 7.07. Undertaking for Costs. The provisions of Section 6.14 of the Original Indenture, in addition to the limitations
set forth therein, shall not apply to any suit instituted by a Holder to enforce its right to receive the consideration due upon conversion of its Notes within the time period prescribed herein. 

Section 7.08. Waiver of Stay or Extension Laws. The Company covenants (to the extent that it may lawfully do so) that it will not
at any time insist upon, or plead, or in any manner whatsoever claim or take the benefit or advantage of, any stay, extension or usury law or other law which would prohibit or forgive the Company from paying all or any portion of the principal of or
Interest on the Notes as contemplated herein, wherever enacted, now or at any time hereafter in force, or which may affect the covenants or the performance of the Indenture; and the Company (to the extent that it may lawfully do so) hereby expressly
waives all benefit or advantage of any such law and covenants that it will not hinder, delay or impede the execution of any power herein granted to the Trustee, but will suffer and permit the execution of every such power as though no such law had
been enacted. 

  
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 ARTICLE 8 

CONSOLIDATION, MERGER, CONVEYANCE, TRANSFER OR LEASE

 Section 8.01. Original Indenture. This Article 8 supersedes in its entirety Article V of the Original Indenture, with the
provisions of Section 8.02 of this Supplemental Indenture superseding the provisions of Section 5.1 of the Original Indenture and the provisions of Section 8.03 of this Supplemental Indenture superseding Section 5.2 of the
Original Indenture. In addition, each reference in the Original Indenture to Section 5.1 of the Original Indenture will, respect to the Notes, be deemed to be a reference to Section 8.02 of this Supplemental Indenture. 

Section 8.02. Consolidation, Merger and Sale of Assets. The Company shall not consolidate with, enter into a binding share
exchange with, or merge with or into, another Person or sell, assign, convey, transfer, lease or otherwise dispose of its properties and assets substantially as an entirety to any successor Person (any such transaction or series of transactions, a
“Merger Transaction”), unless: 
 (a) the successor Person is a corporation organized and existing under the laws of the
United States, any state of the United States or the District of Columbia and, if other than the Company, expressly assumes by supplemental indenture all of the Company’s obligations under the Notes and the Indenture; 

(b) immediately after giving effect to such transaction, no Default or Event of Default shall have occurred and be continuing; and 

(c) the Company shall deliver, or cause to be delivered, to the Trustee an Officers’ Certificate and an Opinion of Counsel, each to the
effect that such Merger Transaction and such supplemental indenture comply with this Article 8. 
 Section 8.03. Successor
Substituted. Upon any such Merger Transaction, the successor Person shall succeed to, and be substituted for, and may exercise every right and power of, the Company under the Indenture with the same effect as if such successor had been named as
the Company herein; and thereafter, and the Company shall be discharged from its obligations under the Notes and this Indenture, except in the case of any lease of all or substantially all of the Company’s assets. For purposes of the foregoing,
any sale, assignment, conveyance, transfer, lease or other disposition of properties and assets of one or more of the Company’s Subsidiaries that would, if the Company had held such properties and assets directly, have constituted the sale,
assignment, conveyance, transfer, lease or disposition of our properties and assets substantially as an entirety shall be treated as such under this Indenture. 

  
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 ARTICLE 9 

REPORTS BY COMPANY 

Section 9.01. Reports by Company. 

This Section 9.01(a) supersedes in its entirety Section 4.2 of the Original Indenture and any reference in the Original Indenture to
such Section 4.2 or any provision therein shall be deemed to refer to this Section 9.01(a) and the corresponding provision herein (if any). So long as any Notes are Outstanding, the Company shall (i) file with the SEC within the time
periods prescribed by its rules and regulations and (ii) furnish to the Trustee and the Holders of the Notes within 15 days after the date on which the Company would be required to file the same with the SEC pursuant to its rules and
regulations (in each case of clauses (i) and (ii), giving effect to any grace period provided by Rule 12b-25 under the Exchange Act), all quarterly and annual financial information required to be contained in Forms 10-Q and 10-K and, with
respect to the annual consolidated financial statements only, a report thereon by our independent auditors. The Company shall not be required to file any report or other information with the SEC if the SEC does not permit such filing, although such
reports shall be required to be furnished to the Trustee. Documents filed by the Company with the SEC via the Electronic Data Gathering and Retrieval (EDGAR) system (or any successor system) shall be deemed to have been furnished to the Trustee and
the Holders of the Notes as of the time such documents are filed via EDGAR. 
 Delivery of such reports, information and documents to the
Trustee is for informational purposes only and the Trustee’s receipt of such shall not constitute notice or constructive notice of any information contained therein or determinable from information contained therein, including the
Company’s compliance with any of the Company’s covenants under this Indenture (as to which the Trustee is entitled to conclusively rely on an Officers’ Certificate). The Trustee shall have no duty whatsoever to determine filing
requirements. 
 ARTICLE 10 

SATISFACTION AND DISCHARGE 

Section 10.01. Original Indenture. This Article 10 supersedes in its entirety the corresponding provisions set forth in Article
VIII of the Original Indenture and any reference in the Original Indenture to such Article VIII or any provision therein shall be deemed to refer this Article 10 or the corresponding provision herein (if any), as the case may be. 

Section 10.02. Discharge of Indenture. When (a) the Company shall deliver to the Trustee for cancellation all Outstanding
Notes theretofore authenticated (other than any Notes that have been destroyed, lost or stolen and in lieu of or in substitution for which other Notes shall have been authenticated and delivered) and not theretofore canceled, or (b) all the
Outstanding Notes not theretofore canceled or delivered to the Trustee for cancellation shall have become due and payable (whether at the Stated Maturity Date, on any Redemption Date or on any Fundamental Change Purchase Date or upon conversion and
determination of related Settlement Amounts or otherwise) and the Company shall deposit with the Trustee, in trust, cash 

  
 51 

 
funds and (in the case of conversion) shares of Common Stock, if any, sufficient to pay all amounts due on all of such Outstanding Notes including principal and Interest due or satisfy the
Company’s conversion obligation, as the case may be, (other than any Notes that shall have been mutilated, destroyed, lost or stolen and in lieu of or in substitution for which other Notes shall have been authenticated and delivered) not
theretofore canceled or delivered to the Trustee for cancellation, and, in each case, the Company shall also pay or cause to be paid all other sums payable under the Indenture by the Company, then the Indenture shall cease to be of further effect
(except as to (i) remaining rights of registration of transfer, substitution and exchange and conversion of Notes, (ii) rights hereunder of Holders to receive payments of principal of and Interest on, or the consideration due upon
conversion of, the Notes and the other rights, duties and obligations of Holders, as beneficiaries hereof with respect to the amounts, if any, so deposited with the Trustee and (iii) the rights, obligations and immunities of the Trustee
hereunder), and the Trustee, on written demand of the Company accompanied by an Officers’ Certificate and an Opinion of Counsel as may be required pursuant to Section 7.2(b) of the Original Indenture and at the cost and expense of the
Company, shall execute proper instruments acknowledging satisfaction and discharge of the Indenture. The Company, however, hereby agrees to reimburse the Trustee for any costs or expenses thereafter reasonably and properly incurred by the Trustee
and to compensate the Trustee for any services thereafter reasonably and properly rendered by the Trustee in connection with the Indenture or the Notes. 

Section 10.03. Deposited Monies and Shares To Be Held in Trust by Trustee. Subject to Section 10.04, all monies and shares of
Common Stock, if any, deposited with the Trustee pursuant to Section 10.02 shall be held in trust for the sole benefit of the Holders, and such monies and shares of Common Stock, if any, shall be applied by the Trustee to the payment, either
directly or through the Paying Agent or Conversion Agent (including the Company if acting as the Paying Agent or Conversion Agent), to the Holders of the particular Notes for the payment or settlement of which such monies or shares of Common Stock
have been deposited with the Trustee, of all sums due and to become due thereon for principal and Interest or the satisfaction of the Company’s conversion obligation, as the case may be, and payment of all other sums due under the Indenture.

 Section 10.04. Paying Agent or Conversion Agent To Repay Monies and Shares Held. Upon the satisfaction and discharge of the
Indenture, all monies and shares of Common Stock, if any, then held by the Paying Agent or Conversion Agent (if other than the Trustee) shall, upon written request of the Company, be repaid or delivered to the Company or paid or delivered to the
Trustee, and thereupon such Paying Agent or Conversion Agent shall be released from all further liability with respect to such monies and shares of Common Stock, if any. 

Subject to the requirements of applicable law, any monies and shares of Common Stock deposited with or paid to the Trustee for payment of the
principal of or Interest on or other obligations under, or to satisfy the Company’s conversion obligation with respect to, the Notes and not applied but remaining unclaimed by the Holders of the Notes for two years after the date upon which the
principal of or Interest on, or other obligations under, such Notes or the Company’s conversion obligation, as the case may be, shall have become due and payable, shall be repaid or delivered to the Company by the Trustee on demand and all
liability of the Trustee 

  
 52 

 
shall thereupon cease with respect to such monies and shares of Common Stock; and the Holder of any of the Notes shall thereafter look only to the Company for any payment or delivery that such
Holder may be entitled to collect unless an applicable abandoned property law designates another Person. 
 Section 10.05.
Reinstatement. If the Trustee or the Paying Agent or Conversion Agent is unable to apply any money or shares of Common Stock in accordance with Section 10.03 by reason of any order or judgment of any court or governmental authority
enjoining, restraining or otherwise prohibiting such application, the Company’s obligations under the Indenture and the Notes shall be revived and reinstated as though no deposit had occurred pursuant to Section 10.02 until such time as
the Trustee or the Paying Agent or Conversion Agent is permitted to apply all such money or shares of Common Stock in accordance with Section 10.03; provided, however, that if the Company makes any payment of Interest on or
principal of any Note or delivery of shares in respect of its conversion obligation following the reinstatement of its obligations, the Company shall be subrogated to the rights of the Holders of such Notes to receive such payment from the money or
shares of Common Stock held by the Trustee or Paying Agent or Conversion Agent. 
 ARTICLE 11 

SUPPLEMENTAL INDENTURES 

Section 11.01. Supplemental Indentures Without Consent of Holders. The Company and the Trustee at any time and from time to time
may without notice to, or the consent of, any Holder enter into one or more indentures supplemental hereto, in form satisfactory to the Trustee, for any of the following purposes in addition to the purposes set forth in Section 9.1 of the
Original Indenture (as amended hereby with respect to the Notes): 
 (i) to cure any ambiguity, omission, defect or
inconsistency as set forth in an Officers’ Certificate; 
 (ii) to provide for the assumption by a successor corporation
of the obligations of the Company pursuant to Article 8; 
 (iii) to add guarantees with respect to the Notes; 

(iv) to secure the Notes; 

(v) to add to the Company’s covenants for the benefit of the Holders or surrender any rights or power conferred upon the
Company; 
 (vi) to make any change that does not adversely affect the rights of any Holder; 

  
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 (vii) upon the occurrence of a Share Exchange Event, solely to (i) provide
that the Notes are convertible into Reference Property, subject to Article 5 above, and (ii) effect the related changes to the terms of the Notes as described in Section 5.12, in each case, in accordance with the applicable provisions of
this Indenture; 
 (viii) to eliminate, in the aggregate, any one or two Settlement Methods or, in the case of Combination
Settlement, irrevocably elect a Specified Dollar Amount; 
 (ix) to comply with any requirement of the SEC in connection with
the qualification of the Indenture under the Trust Indenture Act; or 
 (x) to conform the provisions of the Indenture to the
section entitled “Description of the Notes” section in the preliminary prospectus supplement dated December 3, 2013, as supplemented by the related pricing term sheet dated December 4, 2013 relating to the offering and sale of
the Notes, as set forth in an Officers’ Certificate. 
 For purposes of the Notes, clauses (a), (b), and (d) of Section 9.1
of the Original Indenture shall be deemed to be deleted in their entirety. 
 Section 11.02. Supplemental Indentures with Consent of
Holders. The Company and the Trustee may amend or supplement the Indenture with respect to the Notes with the consent of the Holders of a majority in aggregate principal amount of the Outstanding Notes (including without limitation, consents
obtained in connection with a repurchase of, or tender or exchange offer for, Notes). In addition, the Holders of a majority in aggregate principal amount of the Outstanding Notes (including without limitation, consents obtained in connection with a
repurchase of, or tender or exchange offer for, Notes) may waive the Company’s compliance in any instance with any provision of the Indenture without notice to the other Holders of Notes. 

Notwithstanding Section 9.3 of the Original Indenture, and in addition to any restrictions set forth in Section 9.3 of the Original
Indenture, no amendment, supplement or waiver may be made without the consent of each Holder of outstanding Notes affected thereby if such amendment, supplement or waiver would: 

(i) change the stated maturity of the principal of or any interest on the Notes; 

(ii) reduce the principal amount of or interest on the Notes; 

(iii) reduce the amount of principal payable upon acceleration of the maturity or redemption of the Notes; 

(iv) change the currency of payment of principal of or Interest on the Notes or change any Note’s Place of Payment; 

(v) impair the right of any Holder to receive payment of principal of and Interest on such Holder’s Notes on or after the
due dates therefor or to institute suit for the enforcement of any payment on, or with respect to, the Notes; 

  
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 (vi) modify the provisions with respect to the Company’s redemption right
pursuant to Article 6 or the purchase rights of the Holders as provided in Article 4, in each case, in a manner adverse to Holders of Notes; 

(vii) change the ranking of the Notes; 

(viii) adversely affect the right of Holders to convert their Notes hereunder, or reduce the Conversion Rate (it being
understood that the Trustee shall have no responsibility for making a determination as to whether such amendment adversely affects the rights of the Holders); or 

(ix) modify provisions with respect to modification, amendment or waiver (including waiver of Events of Default), except to
increase the percentage required for modification, amendment or waiver or to provide for consent of each affected Holder of Notes. 
 ARTICLE
12 
 MISCELLANEOUS 

Section 12.01. Successors. All agreements of the Company and the Trustee in the Indenture and the Notes shall bind their
respective successors. 
 Section 12.02. Multiple Originals. The parties may sign any number of copies of this Supplemental
Indenture. Each signed copy shall be an original, but all of them together represent the same agreement. One signed copy is enough to prove this Supplemental Indenture. The exchange of copies of this Indenture and of signature pages by facsimile or
PDF transmission shall constitute effective execution and delivery of this Indenture as to the parties hereto and may be used in lieu of the original Indenture for all purposes. Signatures of the parties hereto transmitted by facsimile or PDF shall
be deemed to be their original signatures for all purposes. 
 Section 12.03. Calculations. Subject to the immediately following
paragraph, and except as otherwise provided herein, the Company and any agents the Company shall engage shall be responsible for making all calculations called for under the Indenture and the Notes, including, but not limited to, determinations of
the Closing Sale Prices of Common Stock, the Trading Price of the Notes, any adjustments to the Conversion Rate, the consideration deliverable in respect of any conversion and accrued Interest payable on the Notes and whether the Notes are
convertible. The Company shall make all these calculations in good faith and, absent manifest error, its calculations shall be final and binding on Holders. The Company shall provide a schedule of its calculations to each of the Trustee and the
Conversion Agent, and each of the Trustee and Conversion Agent is entitled to rely conclusively upon the accuracy of the Company’s calculations without independent verification. The Trustee shall forward a copy of such schedule to any Holder
upon the request of such Holder. 

  
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 The Trustee (including in its capacities as Bid Solicitation Agent, Conversion Agent, Paying
Agent and Registrar) shall have no responsibility to determine the Trading Price of the Notes or whether the Notes are convertible. 

Section 12.04. Benefits of Supplemental Indenture. Nothing in this Supplemental Indenture or in the Notes, express or implied,
shall give to any Person, other than the parties hereto and their respective successors hereunder and the Holders of Notes, any benefit or any legal or equitable right, remedy or claim under this Supplemental Indenture. 

Section 12.05. Withholding Taxes. Each Holder agrees, and each beneficial owner of an interest in a Note by its acquisition of
such interest is deemed to agree, that if the Company or other applicable withholding agent pays withholding taxes or backup withholding on behalf of the Holder or beneficial owner as a result of an adjustment to the Conversion Rate, the Company or
other applicable withholding agent may, at its option, withhold such amounts from payments of cash and shares of Common Stock on the Note (or, in certain circumstances, against any payments on the Common Stock). 

Section 12.06. Waiver of Jury Trial. EACH OF THE COMPANY AND THE TRUSTEE HEREBY IRREVOCABLY WAIVES, TO THE FULLEST EXTENT
PERMITTED BY APPLICABLE LAW, ANY AND ALL RIGHT TO TRIAL BY JURY IN ANY LEGAL PROCEEDING ARISING OUT OF OR RELATING TO THIS SUPPLEMENTAL INDENTURE, THE NOTES OR THE TRANSACTIONS CONTEMPLATED HEREBY OR THEREBY. 

Section 12.07. Governing Law. THIS SUPPLEMENTAL INDENTURE, AND ANY CLAIM, CONTROVERSY OR DISPUTE ARISING UNDER OR RELATED TO THE
INDENTURE OR THE NOTES, SHALL BE GOVERNED BY AND CALCULATED IN ACCORDANCE WITH THE INTERNAL LAWS OF THE STATE OF NEW YORK. 
 [Remainder
of the page intentionally left blank] 

  
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 IN WITNESS WHEREOF, the parties hereto have caused this Supplemental Indenture to be duly
executed as of the day and year first above written. 
  

			
	ENDOLOGIX, INC.
		
	By:	 	 /s/ Shelley B. Thunen

	Name:	 	Shelley B. Thunen
	Title:	 	Chief Financial Officer and Secretary
	
	WELLS FARGO BANK, NATIONAL ASSOCIATION,as Trustee
		
	By:	 	 /s/ Maddy Hall

	Name:	 	Maddy Hall
	Title:	 	Vice President

 SCHEDULE A 

Make-Whole Table 
 The following table
sets forth the number of Additional Shares to be added to the Conversion Rate for each $1,000 principal amount of Notes pursuant to, and under the circumstances described in, Section 5.02 of this Supplemental Indenture, based on hypothetical
Stock Prices and Effective Dates: 
  

																																									
	 	 	Stock Price	 
	 Effective Date
	 	$	 18.14	  	 	$	 21.00	  	 	$	 24.04	  	 	$	 27.00	  	 	$	 31.25	  	 	$	 35.00	  	 	$	 40.00	  	 	$	 50.00	  	 	$	 60.00	  	 	$	 80.00	  
	 December 10, 2013
	 	 	13.5216	  	 	 	10.0310	  	 	 	7.5708	  	 	 	5.9330	  	 	 	4.3664	  	 	 	3.4517	  	 	 	2.6299	  	 	 	1.6923	  	 	 	1.1903	  	 	 	0.7033	  
	 December 15, 2014
	 	 	13.5216	  	 	 	10.0268	  	 	 	7.3615	  	 	 	5.6229	  	 	 	4.0030	  	 	 	3.0872	  	 	 	2.2922	  	 	 	1.4305	  	 	 	0.9980	  	 	 	0.5891	  
	 December 15, 2015
	 	 	13.5216	  	 	 	9.7743	  	 	 	6.9001	  	 	 	5.0755	  	 	 	3.4399	  	 	 	2.5586	  	 	 	1.8321	  	 	 	1.1008	  	 	 	0.7671	  	 	 	0.4579	  
	 December 15, 2016
	 	 	13.5216	  	 	 	9.1236	  	 	 	6.0387	  	 	 	4.1668	  	 	 	2.5961	  	 	 	1.8187	  	 	 	1.2344	  	 	 	0.7153	  	 	 	0.5120	  	 	 	0.3152	  
	 December 15, 2017
	 	 	13.5216	  	 	 	7.9004	  	 	 	4.5449	  	 	 	2.6994	  	 	 	1.3786	  	 	 	0.8538	  	 	 	0.5370	  	 	 	0.3372	  	 	 	0.2554	  	 	 	0.1644	  
	 December 15, 2018
	 	 	13.5216	  	 	 	6.0139	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  

 EXHIBIT A 

[FORM OF FACE OF SECURITY] 

[INCLUDE IF A GLOBAL SECURITY] 
 [UNLESS THIS
CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION (“DTC”), TO THE COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS
REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC (AND ANY PAYMENT IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF
DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 

THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO, AND IS REGISTERED IN THE NAME OF THE DEPOSITORY OR A NOMINEE
OF THE DEPOSITORY. THIS SECURITY IS EXCHANGEABLE FOR SECURITIES REGISTERED IN THE NAME OF A PERSON OTHER THAN THE DEPOSITORY OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE, AND MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY
THE DEPOSITORY TO A NOMINEE OF THE DEPOSITORY, BY A NOMINEE OF THE DEPOSITORY TO THE DEPOSITORY OR ANOTHER NOMINEE OF THE DEPOSITORY OR BY THE DEPOSITORY OR ANY SUCH NOMINEE TO A SUCCESSOR DEPOSITORY OR A NOMINEE OF SUCH SUCCESSOR DEPOSITORY.] 

  
 A-1 

 ENDOLOGIX, INC. 
  

			
	No.     	 	Initially $[        ]

 2.25% Convertible Senior Note due 2018 

CUSIP No.: [    ] 

ISIN Number: [    ] 

ENDOLOGIX, INC., a Delaware corporation, promises to pay to [CEDE & CO., or its registered assigns]1, the principal sum of          DOLLARS, [as revised by the Schedule of Increases or Decreases in Global Security attached hereto,]2 on December 15, 2018. 
 Interest Payment Dates: June 15 and December 15
(or, if any such day is not a Business Day, the immediately following Business Day) commencing on June 15, 2014. 
 Interest Record
Dates: June 1 and December 1. 
 Reference is made to the further provisions of this Note set forth on the reverse hereof,
including, without limitation, provisions giving the Holder of this Note the right to convert this Note into cash, shares of Common Stock or a combination thereof, at the Company’s election, on the terms and subject to the limitations referred
to on the reverse hereof and as more fully specified in the Indenture. Such further provisions shall for all purposes have the same effect as though fully set forth at this place. 

In the case of any conflict between this Note and the Indenture, the provisions of the Indenture shall control. 

This Note shall not be valid or become obligatory for any purpose until the certificate of authentication hereon shall have been manually
signed by the Trustee or a duly authorized authenticating agent under the Indenture. 
  

 

	1 	Use bracketed language for a Global Security. 

	2 	Use bracketed language for a Global Security. 

  
 A-2 

 IN WITNESS WHEREOF, the Company has caused this Note to be duly executed. 

 

			
	ENDOLOGIX, INC.
		
	By:	 	  

	Name:	 	
	Title:	 	

 TRUSTEE’S CERTIFICATE OF AUTHENTICATION 

This is one of the Securities of the series designated herein issued under the within-mentioned Indenture. 

WELLS FARGO BANK, NATIONAL ASSOCIATION 
 as Trustee 

 

			
	By:	 	  

		 	Authorized Signatory

			
		
	Dated:	 	  

  
 A-3 

 [FORM OF REVERSE OF NOTE] 

ENDOLOGIX, INC. 
 2.25% Convertible
Senior Note due 2018 
  

	1.	Interest 

 ENDOLOGIX, INC., a Delaware corporation (such corporation, and its successors
and assigns under the Indenture, the “Company”), promises to pay Interest on the principal amount of this Note at the rate of 2.25% per annum. The Company will pay Interest semiannually on June 15 and December 15 of
each year, commencing on June 15, 2014 (or, if any such day is not a Business Day, the immediately following Business Day). Interest on this Note will accrue from the most recent date to which Interest has been paid or, if no Interest has been
paid, from December 10, 2013. Interest will be computed on the basis of a 360-day year of twelve 30-day months. The Company shall pay Interest (including post-petition Interest in any proceeding under any Bankruptcy Law) on overdue principal
and premium, if any, from time to time on demand at the rate of Interest then in effect; and it shall pay Interest (including post-petition Interest in any proceeding under any Bankruptcy Law) on overdue installments of Interest (without regard to
any applicable grace periods) from time to time on demand at the same rate to the extent lawful. 
  

	2.	Paying Agent, Registrar and Conversion Agent 

 Initially, Wells Fargo Bank, National
Association (the “Trustee”), will act as Paying Agent, Registrar and Conversion Agent. The Company may appoint and change any Paying Agent, Registrar or Conversion Agent in accordance with the terms of the Indenture. The Company may
act as Paying Agent, Registrar or Conversion Agent. 
  

	3.	Indenture 

 The Company issued the Notes under an Indenture dated as of December 10,
2013 (the “Original Indenture”), as supplemented by the First Supplemental Indenture dated as of December 10, 2013 (the “Supplemental Indenture” and the Original Indenture, as supplemented by the First
Supplemental Indenture, the “Indenture”), between the Company and the Trustee. Terms defined in the Indenture and not defined herein have the meanings ascribed thereto in the Indenture. The Notes are subject to all such terms, and
Holders are referred to the Indenture for a statement of those terms. 
 This Note is one of the Securities of the Company, designated as
its 2.25% Convertible Senior Notes due 2018, issued pursuant to the Indenture in an initial aggregate principal amount of $[        ]. Additional Notes may be issued in accordance with the terms of the
Indenture. The Indenture also imposes limitations on the ability of the Company to consolidate or merge with or into any other Person or convey, transfer or lease all or substantially all of the property of the Company. 

  
 A-4 

	4.	Conversion 

 Subject to certain conditions and during certain periods specified in the
Indenture, at any time until the close of business on the second Business Day immediately preceding the Stated Maturity Date of this Note, the Holder hereof has the right, at its option, to convert each $1,000 principal amount of this Note into
cash, shares of Common Stock or a combination of cash and shares of Common Stock, at the Company’s election, determined as set forth in the Indenture, based on the applicable Conversion Rate, as the same may be adjusted from time to time
pursuant to the terms of the Indenture. 
  

	5.	Denominations, Transfer, Exchange 

 The Notes are in registered form without coupons in
denominations of $1,000 and whole multiples of $1,000. A Holder may transfer or exchange Notes in accordance with the terms of the Indenture, subject to certain exceptions set forth therein. Upon any transfer or exchange, the Registrar and the
Trustee may require a Holder, among other things, to furnish appropriate endorsements or transfer documents and to pay any taxes required by law or permitted by the Indenture. 

 

	6.	Persons Deemed Owners 

 The registered Holder of this Note may be treated as the owner of
it for all purposes, subject to certain exceptions specified in the Indenture. 
  

	7.	Defaults and Remedies 

 If an Event of Default (other than an Event of Default relating
to certain events of bankruptcy, insolvency or reorganization of the Company) occurs and is continuing, the Trustee or the Holders of at least 25% in principal amount of the Outstanding Notes may declare the principal of and accrued and unpaid
Interest on all the Notes to be due and payable. If an Event of Default relating to certain events of bankruptcy, insolvency or reorganization of the Company occurs, the principal of and Interest on all the Notes will become immediately due and
payable without any declaration or other act on the part of the Trustee or any Holder. Notwithstanding the foregoing, at the election of the Company, the sole remedy for an Event of Default relating to a failure to file certain reports with the
Commission and the Trustee shall for the first 180 calendar days after such Event of Default consist exclusively of the right to receive Additional Interest. 
  

	8.	No Recourse Against Others 

 A director, officer, employee or stockholder, as such, of
the Company shall not have any liability for any obligations of the Company under the Notes or the Indenture or for any claim based on, in respect of or by reason of such obligations or their creation. By accepting a Note, each Holder waives and
releases all such liability. The waiver and release are part of the consideration for the issue of the Notes. 

  
 A-5 

	9.	Authentication 

 This Note shall not be valid until an authorized signatory of the
Trustee (or an authenticating agent) manually signs the certificate of authentication on the other side of this Note. 
  

	10.	Abbreviations 

 Customary abbreviations may be used in the name of a Holder or an
assignee, such as TEN COM (=tenants in common), TEN ENT (=tenants by the entireties), JT TEN (=joint tenants with rights of survivorship and not as tenants in common), CUST (=custodian), and U/G/M/A (=Uniform Gift to Minors Act). 

 

	11.	GOVERNING LAW 

 THIS NOTE, AND ANY CLAIM, CONTROVERSY OR DISPUTE ARISING UNDER OR RELATED
TO THE INDENTURE OR THE NOTES, SHALL BE GOVERNED BY AND CALCULATED IN ACCORDANCE WITH THE INTERNAL LAWS OF THE STATE OF NEW YORK. 
  

	12.	CUSIP and ISIN Numbers 

 The Company has caused CUSIP and ISIN numbers to be printed on
the Notes and the Trustee shall use the CUSIP and ISIN numbers in notices as a convenience to Holders, provided, that any such notice may state that no representation is made as to the correctness or accuracy of the CUSIP and ISIN numbers
printed in the notice or on the Notes, and that reliance may be placed only on the other identification numbers printed on the Notes, and that the validity of any such notice shall not be affected by any defect in or omission of any such numbers.

 The Company will furnish to any Holder of Notes upon written request and without charge to the Holder a copy of the Indenture which
has in it the text of this Note. 

  
 A-6 

 SCHEDULE OF INCREASES AND DECREASES IN GLOBAL
SECURITY3 
 The following increases or decreases in this Global Security have been made: 

 

									
	 Date of

Exchange
	 	 Amount of decrease in
principal amount of this
Global
Security
	 	 Amount of increase in

principal amount of this
 Global
Security
	 	 Principal amount of this

Global Security
 following such
decrease
 or increase
	 	 Signature of

authorized
 signatory of

Trustee or
 Custodian

	  
	 	  
	 	  
	 	  
	 	  

	  
	 	  
	 	  
	 	  
	 	  

	  
	 	  
	 	  
	 	  
	 	  

	  
	 	  
	 	  
	 	  
	 	  

	  
	 	  
	 	  
	 	  
	 	  

	  
	 	  
	 	  
	 	  
	 	  

	  
	 	  
	 	  
	 	  
	 	  

	  
	 	  
	 	  
	 	  
	 	  

	  
	 	  
	 	  
	 	  
	 	  

	  
	 	  
	 	  
	 	  
	 	  

	  
	 	  
	 	  
	 	  
	 	  

	  
	 	  
	 	  
	 	  
	 	  

	  
	 	  
	 	  
	 	  
	 	  

  
  

	3 	For Global Securities only. 

  
 A-7 

 [FORM OF CONVERSION NOTICE] 

To: Endologix, Inc. 
 The undersigned registered
owner of this Note hereby irrevocably exercises the option to convert this Note, or the portion thereof (which is $1,000 or a multiple thereof) below designated, into, cash, shares of Common Stock of Endologix, Inc. or a combination of cash and
shares of Common Stock, at the Company’s election, in accordance with the terms of the Indenture referred to in this Note, and directs that the check in payment for cash, if any, and the shares, if any, issuable and deliverable upon such
conversion, together with any check in payment for fractional shares and any Notes representing any unconverted principal amount hereof, be issued and delivered to the registered Holder hereof unless a different name has been indicated below. 

If shares or any portion of this Note not converted are to be issued in the name of a Person other than the undersigned, the undersigned will
provide the appropriate information below and pay all transfer taxes payable with respect thereto. In addition, subject to certain exceptions in the Indenture, if this notice is being delivered on a date after the close of business on a Record Date
and prior to the open of business on the related Interest Payment Date, this notice is accompanied by payment of an amount equal to the Interest payable on such Interest Payment Date of the principal of this Note to be converted. 

Capitalized terms used herein but not defined shall have the meanings ascribed to such terms in the Indenture. 

 

			
	Dated:                     	 	
		
		 	  

		
		 	  

		 	Signature(s)
		
		 	Signature(s) must be guaranteed by an “eligible guarantor institution” meeting the requirements of the Registrar, which requirements include membership or participation in the Security Transfer Agent Medallion Program
(“STAMP”) or such other “signature guarantee program” as may be determined by the Registrar in addition to, or in substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934, as amended.
		
		 	  

		 	Signature Guarantee

  
 A-8 

 Fill in the registration of shares of Common Stock, if any, if to be issued, and Notes, if any,
to be delivered, and the person to whom cash, if any, and payment for fractional shares, if any, is to be made, if other than to and in the name of the registered Holder: 
  

			
	Please print name and address
	
	  

	(Name)	 	
	
	  

	(Street Address)
	
	  

	(City, State and Zip Code)

 Principal amount to be converted 

  (if less than all, must be $1,000 or whole multiples thereof): 
  

			
	$            
	
	Social Security or Other Taxpayer
	  Identification Number:
	
	  

 NOTICE: The signature on this Conversion Notice must correspond with the name as written upon the face of the Notes in every
particular without alteration or enlargement or any change whatever. 

  
 A-9 

 [FORM OF FUNDAMENTAL CHANGE PURCHASE NOTICE] 

To: Endologix, Inc. 
 The undersigned registered owner of this
Note hereby acknowledges receipt of a notice from Endologix, Inc. (the “Company”) as to the occurrence of a Fundamental Change with respect to the Company and specifying the Fundamental Change Purchase Date and requests and
instructs the Company to purchase from the registered holder hereof in accordance with the applicable provisions of the Indenture referred to in this Note (1) the entire principal amount of this Note, or the portion thereof (that is $1,000
principal amount or an integral multiple thereof) below designated, and (2) if such Fundamental Change Purchase Date does not fall during the period after a Record Date and on or prior to the corresponding Interest Payment Date, accrued and
unpaid Interest thereon to, but excluding, such Fundamental Change Purchase Date. 
 In the case of Physical Securities, the certificate numbers of the
Notes to be purchased are as set forth below: 
  

			
	Dated:                     	 	
		 	  

		 	Signature(s)
		 	  

		 	 Social Security or Other Taxpayer Identification Number
  

principal amount to be repaid (if less than all): $        ,000

 
 NOTICE: The signature on the Fundamental Change Purchase Notice must correspond with the
name as written upon the face of the Note in every particular without alteration or enlargement or any change whatever.

  
 A-10 

 [FORM OF ASSIGNMENT AND TRANSFER] 

For value received
                             hereby sell(s), assign(s) and transfer(s) unto
                         (Please insert social security or Taxpayer Identification Number of assignee) the within Note, and
hereby irrevocably constitutes and appoints                              attorney to transfer the said Note
on the books of the Company, with full power of substitution in the premises. 
  

			
	Dated:                     	 	
		
		 	  

		
		 	  

		 	Signature(s)
		
		 	Signature(s) must be guaranteed
		 	by an institution which is a member of one of the following recognized signature Guarantee Programs:
		
		 	(i) The Securities Transfer Agent Medallion Program (STAMP); (ii) The New York Stock Exchange Medallion Program (MNSP); (iii) The Stock Exchange Medallion Program (SEMP) or (iv) another guarantee program acceptable to the
Trustee.
		
		 	  

		
		 	  

		 	Signature Guarantee

  
 B-1EX-4.11

 Exhibit 4.11 

CEMPRA, INC. 
 and 

                        
                , as Trustee 
 INDENTURE 

Dated as of                     , 

TABLE OF CONTENTS 
  

							
	 	 	 	  	PAGE	 
		
	 ARTICLE 1      DEFINITIONS AND INCORPORATION BY REFERENCE
	  	 	1	  
			
	 1.1.
	 	 DEFINITIONS
	  	 	1	  
			
	 1.2.
	 	 OTHER DEFINITIONS
	  	 	4	  
			
	 1.3.
	 	 INCORPORATION BY REFERENCE OF TRUST INDENTURE ACT
	  	 	5	  
			
	 1.4.
	 	 RULES OF CONSTRUCTION
	  	 	5	  
		
	 ARTICLE 2      THE SECURITIES
	  	 	5	  
			
	 2.1.
	 	 ISSUABLE IN SERIES
	  	 	5	  
			
	 2.2.
	 	 ESTABLISHMENT OF TERMS OF SERIES OF SECURITIES
	  	 	6	  
			
	 2.3.
	 	 EXECUTION AND AUTHENTICATION
	  	 	7	  
			
	 2.4.
	 	 REGISTRAR AND PAYING AGENT
	  	 	8	  
			
	 2.5.
	 	 PAYING AGENT TO HOLD ASSETS IN TRUST
	  	 	9	  
			
	 2.6.
	 	 SECURITYHOLDER LISTS
	  	 	9	  
			
	 2.7.
	 	 TRANSFER AND EXCHANGE
	  	 	9	  
			
	 2.8.
	 	 REPLACEMENT SECURITIES
	  	 	10	  
			
	 2.9.
	 	 OUTSTANDING SECURITIES
	  	 	10	  
			
	 2.10.
	 	 WHEN TREASURY SECURITIES DISREGARDED; DETERMINATION OF HOLDERS’ ACTION
	  	 	11	  
			
	 2.11.
	 	 TEMPORARY SECURITIES
	  	 	11	  
			
	 2.12.
	 	 CANCELLATION
	  	 	11	  
			
	 2.13.
	 	 PAYMENT OF INTEREST; DEFAULTED INTEREST; COMPUTATION OF INTEREST
	  	 	11	  
			
	 2.14.
	 	 CUSIP NUMBER
	  	 	12	  
			
	 2.15.
	 	 PROVISIONS FOR GLOBAL SECURITIES
	  	 	12	  
			
	 2.16.
	 	 PERSONS DEEMED OWNERS
	  	 	13	  

							
		
	 ARTICLE 3      REDEMPTION
	  	 	13	  
			
	 3.1.
	 	 NOTICES TO TRUSTEE
	  	 	13	  
			
	 3.2.
	 	 SELECTION BY TRUSTEE OF SECURITIES TO BE REDEEMED
	  	 	13	  
			
	 3.3.
	 	 NOTICE OF REDEMPTION
	  	 	13	  
			
	 3.4.
	 	 EFFECT OF NOTICE OF REDEMPTION
	  	 	14	  
			
	 3.5.
	 	 DEPOSIT OF REDEMPTION PRICE
	  	 	14	  
			
	 3.6.
	 	 SECURITIES REDEEMED IN PART
	  	 	15	  
		
	 ARTICLE 4      COVENANTS
	  	 	15	  
			
	 4.1.
	 	 PAYMENT OF SECURITIES
	  	 	15	  
			
	 4.2.
	 	 SEC REPORTS
	  	 	15	  
			
	 4.3.
	 	 WAIVER OF STAY, EXTENSION OR USURY LAWS
	  	 	15	  
			
	 4.4.
	 	 COMPLIANCE CERTIFICATE
	  	 	15	  
			
	 4.5.
	 	 CORPORATE EXISTENCE
	  	 	16	  
		
	 ARTICLE 5      SUCCESSOR CORPORATION
	  	 	16	  
			
	 5.1.
	 	 LIMITATION ON CONSOLIDATION, MERGER AND SALE OF ASSETS
	  	 	16	  
			
	 5.2.
	 	 SUCCESSOR PERSON SUBSTITUTED
	  	 	17	  
		
	 ARTICLE 6      DEFAULTS AND REMEDIES
	  	 	17	  
			
	 6.1.
	 	 EVENTS OF DEFAULT
	  	 	17	  
			
	 6.2.
	 	 ACCELERATION
	  	 	18	  
			
	 6.3.
	 	 REMEDIES
	  	 	18	  
			
	 6.4.
	 	 WAIVER OF PAST DEFAULTS AND EVENTS OF DEFAULT
	  	 	18	  
			
	 6.5.
	 	 CONTROL BY MAJORITY
	  	 	18	  
			
	 6.6.
	 	 LIMITATION ON SUITS
	  	 	19	  
			
	 6.7.
	 	 RIGHTS OF HOLDERS TO RECEIVE PAYMENT
	  	 	19	  
			
	 6.8.
	 	 COLLECTION SUIT BY TRUSTEE
	  	 	19	  
			
	 6.9.
	 	 TRUSTEE MAY FILE PROOFS OF CLAIM
	  	 	19	  
			
	 6.10.
	 	 PRIORITIES
	  	 	20	  
			
	 6.11.
	 	 UNDERTAKING FOR COSTS
	  	 	20	  
		
	 ARTICLE 7      TRUSTEE
	  	 	20	  
			
	 7.1.
	 	 DUTIES OF TRUSTEE
	  	 	20	  
			
	 7.2.
	 	 RIGHTS OF TRUSTEE
	  	 	21	  

							
			
	 7.3.
	 	 INDIVIDUAL RIGHTS OF TRUSTEE
	  	 	22	  
			
	 7.4.
	 	 TRUSTEE’S DISCLAIMER
	  	 	22	  
			
	 7.5.
	 	 NOTICE OF DEFAULT
	  	 	22	  
			
	 7.6.
	 	 REPORTS BY TRUSTEE TO HOLDERS
	  	 	22	  
			
	 7.7.
	 	 COMPENSATION AND INDEMNITY
	  	 	23	  
			
	 7.8.
	 	 REPLACEMENT OF TRUSTEE
	  	 	23	  
			
	 7.9.
	 	 SUCCESSOR TRUSTEE BY CONSOLIDATION, MERGER OR CONVERSION
	  	 	24	  
			
	 7.10.
	 	 ELIGIBILITY; DISQUALIFICATION
	  	 	24	  
			
	 7.11.
	 	 PREFERENTIAL COLLECTION OF CLAIMS AGAINST COMPANY
	  	 	24	  
			
	 7.12.
	 	 PAYING AGENTS
	  	 	24	  
		
	 ARTICLE 8      AMENDMENTS, SUPPLEMENTS AND WAIVERS
	  	 	25	  
			
	 8.1.
	 	 WITHOUT CONSENT OF HOLDERS
	  	 	25	  
			
	 8.2.
	 	 WITH CONSENT OF HOLDERS
	  	 	25	  
			
	 8.3.
	 	 COMPLIANCE WITH TRUST INDENTURE ACT
	  	 	26	  
			
	 8.4.
	 	 REVOCATION AND EFFECT OF CONSENTS
	  	 	26	  
			
	 8.5.
	 	 NOTATION ON OR EXCHANGE OF SECURITIES
	  	 	27	  
			
	 8.6.
	 	 TRUSTEE TO SIGN AMENDMENTS, ETC.
	  	 	27	  
		
	 ARTICLE 9      DISCHARGE OF INDENTURE; DEFEASANCE
	  	 	27	  
			
	 9.1.
	 	 DISCHARGE OF INDENTURE
	  	 	27	  
			
	 9.2.
	 	 LEGAL DEFEASANCE
	  	 	27	  
			
	 9.3.
	 	 COVENANT DEFEASANCE
	  	 	28	  
			
	 9.4.
	 	 CONDITIONS TO LEGAL DEFEASANCE OR COVENANT DEFEASANCE
	  	 	28	  
			
	 9.5.
	 	 DEPOSITED MONEY AND U.S. AND FOREIGN GOVERNMENT OBLIGATIONS TO BE HELD IN TRUST; OTHER MISCELLANEOUS PROVISIONS
	  	 	29	  
			
	 9.6.
	 	 REINSTATEMENT
	  	 	29	  
			
	 9.7.
	 	 MONEYS HELD BY PAYING AGENT
	  	 	30	  
			
	 9.8.
	 	 MONEYS HELD BY TRUSTEE
	  	 	30	  
		
	 ARTICLE 10    MISCELLANEOUS
	  	 	30	  
			
	 10.1.
	 	 TRUST INDENTURE ACT CONTROLS
	  	 	30	  
			
	 10.2.
	 	 NOTICES
	  	 	30	  
			
	 10.3.
	 	 COMMUNICATIONS BY HOLDERS WITH OTHER HOLDERS
	  	 	31	  
			
	 10.4.
	 	 CERTIFICATE AND OPINION AS TO CONDITIONS PRECEDENT
	  	 	31	  

							
			
	 10.5.
	 	 STATEMENT REQUIRED IN CERTIFICATE AND OPINION
	  	 	32	  
			
	 10.6.
	 	 RULES BY TRUSTEE AND AGENTS
	  	 	32	  
			
	 10.7.
	 	 BUSINESS DAYS; LEGAL HOLIDAYS; PLACE OF PAYMENT
	  	 	32	  
			
	 10.8.
	 	 GOVERNING LAW
	  	 	32	  
			
	 10.9.
	 	 NO ADVERSE INTERPRETATION OF OTHER AGREEMENTS
	  	 	32	  
			
	 10.10.
	 	 NO RECOURSE AGAINST OTHERS
	  	 	33	  
			
	 10.11.
	 	 SUCCESSORS
	  	 	33	  
			
	 10.12.
	 	 MULTIPLE COUNTERPARTS
	  	 	33	  
			
	 10.13.
	 	 TABLE OF CONTENTS, HEADINGS, ETC.
	  	 	33	  
			
	 10.14.
	 	 SEVERABILITY
	  	 	33	  
			
	 10.15.
	 	 SECURITIES IN A FOREIGN CURRENCY OR IN EUROS
	  	 	33	  
			
	 10.16.
	 	 JUDGMENT CURRENCY
	  	 	34	  

 CROSS-REFERENCE TABLE 

 

			
	 TIA SECTION
	 	 INDENTURE SECTION

	310(a)(1)(2)(5)	 	7.10
	310(a)(3)(4)	 	Inapplicable
	310(b)	 	7.8; 7.10
	310(c)	 	Inapplicable
		
	311(a)(b)	 	7.11
	311(c)	 	Inapplicable
		
	312(a)	 	2.6
	312(b)(c)	 	10.3
		
	313(a)(b)	 	7.6
	313(c)	 	7.6; 10.2
	313(d)	 	7.6
		
	314(a)	 	4.2; 4.4; 10.2
	314(b)	 	N/A
	314(c)(1)(2)	 	10.4; 10.5
	314(c)(3)	 	Inapplicable
	314(d)	 	Inapplicable
	314(e)	 	10.5
	314(f)	 	Inapplicable
		
	315(a)	 	7.1, 7.2
	315(b)	 	7.5; 10.2
	315(c)	 	7.1
	315(d)	 	7.1; 7.2
	315(e)	 	6.11
		
	316(a)(last sentence)	 	2.10
	316(a)(1)(A)	 	6.5
	316(a)(1)(B)	 	6.4
	316(a)(2)	 	8.2
	316(b)	 	6.7
	316(c)	 	8.4
		
	317(a)(1)	 	6.8
	317(a)(2)	 	6.9
	317(b)	 	2.5; 7.12
		
	318(a)	 	10.1

 Note: This Cross-Reference Table shall not, for any purpose, be deemed to be a part of the Indenture. 

 INDENTURE, dated as of             ,
        , by and between Cempra, Inc., a Delaware corporation, as Issuer (the “Company”) and
                    , a                     
organized under the laws of                     , as Trustee (the “Trustee”). 

RECITALS OF THE COMPANY 

The Company has duly authorized the execution and delivery of this Indenture to provide for the issuance from time to time of its debentures,
notes or other evidences of indebtedness to be issued in one or more series (the “Securities”), as herein provided, up to such principal amount as may from time to time be authorized in or pursuant to one or more resolutions of the Board
of Directors or by supplemental indenture. 
 All things necessary to make this Indenture a valid agreement of the Company in accordance
with its terms have been done, and the execution and delivery thereof have been in all respects duly authorized by the parties hereto. 

NOW, THEREFORE, THIS INDENTURE WITNESSETH: 

For and in consideration of the premises and the purchase of the Securities by the Holders thereof, it is mutually agreed, for the equal and
proportionate benefit of all Holders of the Securities of a Series thereof, as follows: 
 ARTICLE 1 

DEFINITIONS AND INCORPORATION BY REFERENCE 
  

	1.1.	DEFINITIONS. 

 “Affiliate” of any specified Person means any other Person which,
directly or indirectly through one or more intermediaries, controls, or is controlled by or is under common control with, such specified Person. For the purposes of this definition, “control” (including, with correlative meanings, the
terms “controlling,” “controlled by” and “under common control with”), as used with respect to any Person, means the possession, directly or indirectly, of the power to direct or cause the direction of the management or
policies of such Person, whether through the ownership of voting securities, by agreement or otherwise. 
 “Agent” means any
Registrar, Paying Agent, co-registrar or agent for service of notices and demands. 
 “Board of Directors” means the Board of
Directors of the Company or any committee duly authorized to act therefor. 
 “Board Resolution” means a copy of a resolution
certified pursuant to an Officers’ Certificate to have been duly adopted by the Board of Directors of the Company and to be in full force and effect on the date of such certification which has been delivered to the Trustee. 

“Capital Stock” means, with respect to any Person, any and all shares or other equivalents (however designated) of capital stock,
partnership interests or any other participation, right or other interest in the nature of an equity interest in such Person or any option, warrant or other security convertible into any of the foregoing. 

“Company” means the party named as such in the first paragraph of this Indenture until a successor replaces such party pursuant to
Article 5 of this Indenture, and thereafter means the successor and any other primary obligor on the Securities. 
 “Company
Order” means a written order signed in the name of the Company by two Officers, one of whom must be its Chief Executive Officer or its Chief Financial Officer. 

 “Company Request” means any written request signed in the name of the Company by its
Chief Executive Officer, its President, any Vice President, its Chief Financial Officer or its Treasurer and attested to by its Secretary or any Assistant Secretary. 

“Corporate Trust Office” means the office of the Trustee at which at any particular time its corporate trust business shall be
principally administered. 
 “Default” means any event that is, or that with the passing of time or giving of notice or both would
be, an Event of Default. 
 “Depository” means, with respect to the Securities of any Series issuable or issued in whole or in
part in the form of one or more Global Securities, the Person designated as Depository for such Series by the Company, which Depository shall be a clearing agency registered under the Exchange Act, until a successor Depository shall have become such
pursuant to the applicable provisions of this Indenture, and thereafter “Depository” shall mean each Person who is then a Depository hereunder, and if at any time there is more than one such Person, such Persons. 

“Dollars” means the currency of the United States of America. 

“Euro” means the single currency of participating member states of the economic and monetary union as contemplated in the Treaty on
European Union. 
 “Exchange Act” means the Securities Exchange Act of 1934, as amended. 

“Foreign Currency” means any currency or currency unit issued by a government other than the government of the United States of
America. 
 “Foreign Government Obligations” means, with respect to Securities that are denominated in a Foreign Currency,
(i) direct obligations of the government that issued or caused to be issued such currency for the payment of which obligations its full faith and credit is pledged or (ii) obligations of a Person controlled or supervised by, or acting as
an agency or instrumentality of, such government, the timely payment of which is unconditionally guaranteed as a full faith and credit obligation by such government, which, in either case under clauses (i) and (ii), are not callable or
redeemable at the option of the issuer thereof. 
 “GAAP” means generally accepted accounting principles consistently applied as
in effect in the United States of America from time to time. 
 “Global Security” or “Global Securities” means a
Security or Securities, as the case may be, in the form established pursuant to Section 2.2, evidencing all or part of a Series of Securities issued to the Depository for such Series or its nominee, and registered in the name of such Depository
or nominee, and bearing the legend set forth in Section 2.15(c) (or such other legend(s) as may be applied to such Securities in accordance with Section 2.2(24)). 

“Holder” or “Securityholder” means the Person in whose name a Security is registered on the Registrar’s books. 

“Indebtedness” means (without duplication), with respect to any Person, any indebtedness at any time outstanding, secured or
unsecured, contingent or otherwise, which is for borrowed money (whether or not the recourse of the lender is to the whole of the assets of such Person or only to a portion thereof), or evidenced by bonds, notes, debentures or similar instruments,
or representing the balance deferred and unpaid of the purchase price of any property (excluding any balances that constitute accounts payable or trade payables, and other accrued liabilities arising in the ordinary course of business), if and to
the extent any of the foregoing indebtedness would appear as a liability upon a balance sheet of such Person prepared in accordance with GAAP. 

“Indenture” means this Indenture as amended, restated or supplemented from time to time. 

  
 2 

 “Interest Payment Date,” when used with respect to any Security, means the Stated
Maturity of an installment of interest on such Security. 
 “Lien” means, with respect to any property or assets of any Person,
any mortgage or deed of trust, pledge, hypothecation, assignment, deposit arrangement, security interest, lien, charge, easement, encumbrance, preference, priority or other security agreement or preferential arrangement of any kind or nature
whatsoever on or with respect to such property or assets (including, without limitation, any capitalized lease obligation, conditional sales or other title retention agreement having substantially the same economic effect as any of the foregoing).

 “Maturity,” when used with respect to any Security, means the date on which the principal of such Security, or an installment
of principal, becomes due and payable as therein or herein provided, whether at the Stated Maturity or by declaration of acceleration, call for redemption, notice of option to elect payment or otherwise. 

“Officer” means the Chief Executive Officer, the President, any Vice President, the Chief Financial Officer, the Treasurer or the
Secretary of the Company, or any other officer designated by the Board of Directors, as the case may be. 
 “Officers’
Certificate” means, with respect to any Person, a certificate signed by the Chairman, Chief Executive Officer, President or any Senior or Executive Vice President and the Chief Financial Officer or any Treasurer of such Person, that shall
comply with applicable provisions of this Indenture. 
 “Opinion of Counsel” means a written opinion from legal counsel, which
counsel is reasonably acceptable to the Trustee. The counsel may be an employee of or counsel to the Company. 
 “Person” means
any individual, corporation, limited liability company, partnership, joint venture, association, joint-stock company, trust, unincorporated organization or government (including any agency or political subdivision thereof). 

“Redemption Date,” when used with respect to any Security to be redeemed, means the date fixed for such redemption pursuant to this
Indenture. 
 “Responsible Officer,” when used with respect to the Trustee, means any officer within the corporate trust
department or division of the Trustee (or any successor group of the Trustee) or any other officer of the Trustee customarily performing functions similar to those performed by any of the above designated officers, and also means, with respect to a
particular corporate trust matter, any other officer to whom such matter is referred because of his knowledge of and familiarity with the particular subject. 

“SEC” means the United States Securities and Exchange Commission as constituted from time to time, or any successor performing
substantially the same functions. 
 “Securities” means the securities that are issued under this Indenture, as amended or
supplemented from time to time pursuant to this Indenture. 
 “Securities Act” means the Securities Act of 1933, as amended. 

“Series” or “Series of Securities” means each series of debentures, notes or other debt instruments of the Company created
pursuant to Sections 2.1 and 2.2. 
 “Significant Subsidiary” means (i) any direct or indirect Subsidiary of the Company that
would be a “significant subsidiary” as defined in Article 1, Rule 1-02 of Regulation S-X, promulgated pursuant to the Securities Act, as such regulation is in effect on the date hereof, or (ii) any group of direct or indirect
Subsidiaries of the Company that, taken together as a group, would be a “significant subsidiary” as defined in Article 1, Rule 1-02 of Regulation S-X, promulgated pursuant to the Securities Act, as such regulation is in effect on the date
hereof. 
 “Stated Maturity,” when used with respect to any Security or any installment of principal thereof or interest thereon,
means the date specified in such Security as the fixed date on which the principal of 

  
 3 

 
such Security, or such installment of principal or interest, is due and payable, and when used with respect to any other Indebtedness, means the date specified in the instrument governing such
Indebtedness as the fixed date on which the principal of such Indebtedness, or any installment of interest thereon, is due and payable. 

“Subsidiary” of any specified Person means any corporation, limited liability company, partnership, joint venture, association or
other business entity, whether now existing or hereafter organized or acquired, (i) in the case of a corporation, of which more than 50% of the total voting power of the Capital Stock entitled (without regard to the occurrence of any
contingency) to vote in the election of directors thereof is held, directly or indirectly, by such Person or any of its Subsidiaries; or (ii) in the case of a partnership, joint venture, association or other business entity, with respect to
which such Person or any of its Subsidiaries has the power to direct or cause the direction of the management and policies of such entity by contract or otherwise, or if in accordance with GAAP such entity is consolidated with such Person for
financial statement purposes. 
 “TIA” means the Trust Indenture Act of 1939 (15 U.S. Code Section 77aaa-77bbbb) as in effect
on the date of this Indenture (except as provided in Section 8.3). 
 “Trustee” means the party named as such in this
Indenture until a successor replaces it pursuant to this Indenture, and thereafter means the successor, and if at any time there is more than one such Person, “Trustee” as used with respect to the Securities of any Series shall mean the
Trustee with respect to Securities of that Series. 
 “U.S. Government Obligations” means direct non-callable obligations of, or
non-callable obligations guaranteed by, the United States of America for the payment of which obligation or guarantee the full faith and credit of the United States of America is pledged. 

 

	1.2.	OTHER DEFINITIONS. 

 The definitions of the following terms may be found in the sections
indicated as follows: 
  

			
	 TERM
	  	 DEFINED IN SECTION

		
	 “Bankruptcy Law”
	  	6.1
		
	 “Business Day”
	  	10.7
		
	 “Covenant Defeasance”
	  	9.3
		
	 “Custodian”
	  	6.1
		
	 “Event of Default”
	  	6.1
		
	 “Journal”
	  	10.15
		
	 “Judgment Currency”
	  	10.16
		
	 “Legal Defeasance”
	  	9.2
		
	 “Legal Holiday”
	  	10.7
		
	 “Market Exchange Rate”
	  	10.15
		
	 “New York Paying Agent”
	  	2.4
		
	 “Paying Agent”
	  	2.4
		
	 “Place of Payment”
	  	10.7
		
	 “Registrar”
	  	2.4
		
	 “Required Currency”
	  	10.16
		
	 “Service Agent”
	  	2.4

  
 4 

	1.3.	INCORPORATION BY REFERENCE OF TRUST INDENTURE ACT. 

 Whenever this Indenture refers to a
provision of the TIA, the portion of such provision required to be incorporated herein in order for this Indenture to be qualified under the TIA is incorporated by reference in and made a part of this Indenture. The following TIA terms used in this
Indenture have the following meanings: 
 “Commission” means the SEC. 

“indenture securities” means the Securities. 

“indenture securityholder” means a Holder or Securityholder. 

“indenture to be qualified” means this Indenture. 

“indenture trustee” or “institutional trustee” means the Trustee. 

“obligor on the indenture securities” means the Company. 

All other terms used in this Indenture that are defined by the TIA, defined in the TIA by reference to another statute or defined by SEC rule
have the meanings therein assigned to them. 
  

	1.4.	RULES OF CONSTRUCTION. 

 Unless the context otherwise requires: 

(1) a term has the meaning assigned to it herein, whether defined expressly or by reference; 

(2) an accounting term not otherwise defined has the meaning assigned to it in accordance with GAAP; 

(3) “or” is not exclusive; 

(4) words in the singular include the plural, and in the plural include the singular; 

(5) words used herein implying any gender shall apply to each gender; and 

(6) the words “herein”, “hereof” and “hereunder” and other words of similar import refer to this Indenture as a
whole and not to any particular Article, Section or other subdivision. 
 ARTICLE 2 

THE SECURITIES 
  

	2.1.	ISSUABLE IN SERIES. 

 The aggregate principal amount of Securities that may be authenticated and
delivered under this Indenture is $[        ]. The Securities may be issued in one or more Series. All Securities of a Series shall be identical except as may be set forth in a Board Resolution, a supplemental
indenture or an Officers’ Certificate detailing the adoption of the terms thereof pursuant to the authority granted under a Board Resolution. In the case of Securities of a Series to be issued from time to time, the Board Resolution,
Officers’ Certificate or supplemental indenture may provide for the method by which specified terms (such as interest rate, Stated Maturity, record date or date from which interest shall accrue) are to be determined. Securities may differ
between Series in respect of any matters, PROVIDED, that all Series of Securities shall be equally and ratably entitled to the benefits of the Indenture. 

  
 5 

	2.2.	ESTABLISHMENT OF TERMS OF SERIES OF SECURITIES. 

 At or prior to the issuance of any Securities
within a Series, the following shall be established (as to the Series generally, in the case of Subsection 2.2(1) and either as to such Securities within the Series or as to the Series generally in the case of Subsections 2.2(2) through 2.2(24)) by
a Board Resolution, a supplemental indenture or an Officers’ Certificate, in each case, pursuant to authority granted under a Board Resolution: 

(1) the title of the Series (which shall distinguish the Securities of that particular Series from the Securities of any other Series); 

(2) any limit upon the aggregate principal amount of the Securities of the Series which may be authenticated and delivered under this
Indenture (except for Securities authenticated and delivered upon registration of transfer of, or in exchange for, or in lieu of, other Securities of the Series pursuant to Section 2.7, 2.8, 2.11, 3.6 or 8.5); 

(3) the price or prices (expressed as a percentage of the principal amount thereof) at which the Securities of the Series will be issued; 

(4) the date or dates on which the principal of the Securities of the Series is payable; 

(5) the rate or rates (which may be fixed or variable) per annum or, if applicable, the method used to determine such rate or rates
(including, but not limited to, any commodity, commodity index, stock exchange index or financial index) at which the Securities of the Series shall bear interest, if any, the date or dates from which such interest, if any, shall accrue, the date or
dates on which such interest, if any, shall commence and be payable and any regular record date for the interest payable on any Interest Payment Date; 

(6) the place or places where the principal of, and interest and premium, if any, on, the Securities of the Series shall be payable, or the
method of such payment, if by wire transfer, mail or other means; 
 (7) if applicable, the period or periods within which, the price or
prices at which and the terms and conditions upon which the Securities of the Series may be redeemed, in whole or in part, at the option of the Company; 

(8) the obligation, if any, of the Company to redeem or purchase the Securities of the Series pursuant to any sinking fund or analogous
provisions or at the option of a Holder thereof, and the period or periods within which, the price or prices at which and the terms and conditions upon which Securities of the Series shall be redeemed or purchased, in whole or in part, pursuant to
such obligation; 
 (9) the dates, if any, on which and the price or prices at which the Securities of the Series will be repurchased by the
Company at the option of the Holders thereof, and other detailed terms and provisions of such repurchase obligations; 
 (10) if other than
denominations of $1,000 and any integral multiple thereof, the denominations in which the Securities of the Series shall be issuable; 

(11) the forms of the Securities of the Series in bearer (if to be issued outside of the United States of America) or fully registered form
(and, if in fully registered form, whether the Securities will be issuable as Global Securities); 
 (12) if other than the principal amount
thereof, the portion of the principal amount of the Securities of the Series that shall be payable upon declaration of acceleration of the Maturity thereof pursuant to Section 6.2; 

  
 6 

 (13) the currency of denomination of the Securities of the Series, which may be Dollars or any
Foreign Currency, including, but not limited to, the Euro, and, if such currency of denomination is a composite currency other than the Euro, the agency or organization, if any, responsible for overseeing such composite currency; 

(14) the designation of the currency, currencies or currency units in which payment of the principal of, and interest and premium, if any, on,
the Securities of the Series will be made; 
 (15) if payments of principal of, or interest or premium, if any, on, the Securities of the
Series are to be made in one or more currencies or currency units other than that or those in which such Securities are denominated, the manner in which the exchange rate with respect to such payments will be determined; 

(16) the manner in which the amounts of payment of principal of, or interest and premium, if any, on, the Securities of the Series will be
determined, if such amounts may be determined by reference to an index based on a currency or currencies or by reference to a commodity, commodity index, stock exchange index or financial index; 

(17) the provisions, if any, relating to any collateral provided for the Securities of the Series; 

(18) any addition to or change in the covenants set forth in Articles 4 or 5 that applies to Securities of the Series; 

(19) any addition to or change in the Events of Default which applies to any Securities of the Series, and any change in the right of the
Trustee or the requisite Holders of such Securities to declare the principal amount thereof due and payable pursuant to Section 6.2; 

(20) the terms and conditions, if any, for conversion of the Securities into or exchange of the Securities for shares of common stock or
preferred stock of the Company that apply to Securities of the Series; 
 (21) any depositories, interest rate calculation agents, exchange
rate calculation agents or other agents with respect to Securities of such Series if other than those appointed herein; 
 (22) the terms
and conditions, if any, upon which the Securities shall be subordinated in right of payment to other Indebtedness of the Company; 
 (23) if
applicable, that the Securities of the Series, in whole or any specified part, shall be defeasible pursuant to Article 9; and 
 (24) any
other terms of the Securities of the Series (which terms shall not be inconsistent with the provisions of this Indenture, except as permitted by Section 8.1, but which may modify or delete any provision of this Indenture insofar as it applies
to such Series). 
 All Securities of any one Series need not be issued at the same time, and may be issued from time to time, consistent
with the terms of this Indenture, if so provided by or pursuant to the Board Resolution, supplemental indenture or Officers’ Certificate referred to above, however, the authorized principal amount of any Series may not be increased to provide
for issuances of additional Securities of such Series, unless otherwise provided in such Board Resolution, supplemental indenture or Officers’ Certificate. 
  

	2.3.	EXECUTION AND AUTHENTICATION. 

 The Securities shall be executed on behalf of the Company by two
Officers of the Company or an Officer and an Assistant Secretary of the Company. Each such signature may be either manual or facsimile. The Company’s seal may be impressed, affixed, imprinted or reproduced on the Securities and may be in
facsimile form. 

  
 7 

 If an Officer whose signature is on a Security no longer holds that office at the time the
Security is authenticated, the Security shall nevertheless be valid. 
 A Security shall not be valid until authenticated by the manual
signature of the Trustee or an authenticating agent. The signature shall be conclusive evidence that the Security has been authenticated under this Indenture. The Trustee shall at any time, and from time to time, authenticate Securities for original
issue in the principal amount provided in the Board Resolution, supplemental indenture hereto or Officers’ Certificate, upon receipt by the Trustee of a Company Order. Such Company Order may authorize authentication and delivery pursuant to
oral or electronic instructions from the Company or its duly authorized agent or agents, which oral instructions shall be promptly confirmed in writing. Each Security shall be dated the date of its authentication. 

The aggregate principal amount of Securities of any Series outstanding at any time may not exceed any limit upon the maximum principal amount
for such Series set forth in the Board Resolution, supplemental indenture hereto or Officers’ Certificate delivered pursuant to Section 2.2, except as provided in Section 2.8. 

Prior to the issuance of Securities of any Series, the Trustee shall have received and (subject to Section 7.1) shall be fully protected
in relying on: (a) the Board Resolution, supplemental indenture hereto or Officers’ Certificate establishing the form of the Securities of that Series or of Securities within that Series and the terms of the Securities of that Series or of
Securities within that Series, (b) an Officers’ Certificate complying with Section 10.4, and (c) an Opinion of Counsel complying with Section 10.4. 

The Trustee shall have the right to decline to authenticate and deliver any Securities of any Series: (a) if the Trustee, being advised
in writing by outside counsel, determines that such action may not lawfully be taken; or (b) if the Trustee in good faith by its board of directors or trustees, executive committee or a trust committee of directors and/or vice-presidents shall
reasonably determine that such action would expose the Trustee to personal liability, or cause it to have a conflict of interest with respect to Holders of any then outstanding Series of Securities. 

The Trustee may appoint an authenticating agent acceptable to the Company to authenticate Securities. An authenticating agent may authenticate
Securities whenever the Trustee may do so. Any appointment shall be evidenced by an instrument signed by an authorized officer of the Trustee, a copy of which shall be furnished to the Company. Each reference in this Indenture to authentication by
the Trustee includes authentication by such agent. An authenticating agent has the same rights as an Agent to deal with the Company or an Affiliate of the Company. 
  

	2.4.	REGISTRAR AND PAYING AGENT. 

 The Company shall maintain in each Place of Payment for any Series
of Securities (i) an office or agency where such Securities may be presented for registration of transfer or for exchange (“Registrar”), (ii) an office or agency where such Securities may be presented for payment (“Paying
Agent”) (PROVIDED that the Company shall at all times maintain a Paying Agent in the Borough of Manhattan, City of New York, State of New York (the “New York Paying Agent”), and PROVIDED, FURTHER, that at the option of the Company
payment of interest may be made by check mailed to the address of the Person entitled thereto as such address shall appear in the register for the Securities maintained by the Registrar), and (iii) an office or agency where notices and demands
to or upon the Company in respect of the Securities and this Indenture may be served (“Service Agent”). The Registrar shall keep a register of the Securities and of their transfer and exchange. The Company may have one or more
co-registrars and one or more additional paying agents. The Company shall give prompt written notice to the Trustee of the location, and any change in the location, of such office or agency. If at any time the Company shall fail to maintain any such
required office, or to furnish the Trustee with the address thereof, such presentations, surrenders, notices and demands may be made or served at the address of the Trustee as set forth in Section 10.2. If the Company acts as Paying Agent, it
shall segregate the money held by it for the payment of principal of, and interest and premium, if any, on, the Securities and hold it as a separate trust fund. The Company may change any Paying Agent, Registrar, co-registrar or any other Agent
without notice to any Securityholder. 

  
 8 

 The Company may also from time to time designate one or more other offices or agencies where the
Securities may be presented or surrendered for any or all such purposes, and may from time to time rescind such designations; PROVIDED, HOWEVER, that no such designation or rescission shall in any manner relieve the Company of its obligation to
maintain an office or agency in each Place of Payment for Securities of any Series for such purposes. The Company hereby initially designates the Corporate Trust Office of the Trustee as such office of the Company. The Company shall give prompt
written notice to the Trustee of such designation or rescission, and of any change in the location of any such other office or agency. 

The Company shall enter into an appropriate agency agreement with any Registrar or Paying Agent not a party to this Indenture. The agreement
shall implement the provisions of this Indenture that relate to such Agent. The Company shall notify the Trustee of the name and address of any such Agent. If the Company fails to maintain a Registrar or Paying Agent, or agent for service of notices
and demands, or fails to give the foregoing notice, the Trustee shall act as such. The Company hereby appoints the Trustee as the initial Registrar, Paying Agent and Service Agent for each Series unless another Registrar, Paying Agent or Service
Agent, as the case may be, is appointed prior to the time Securities of that Series are first issued. The Company designates                     , as
the New York Paying Agent, with offices at                     . 
  

	2.5.	PAYING AGENT TO HOLD ASSETS IN TRUST. 

 The Trustee as Paying Agent shall, and the Company shall
require each Paying Agent other than the Trustee to agree in writing that each Paying Agent shall, hold in trust for the benefit of the Holders of any Series of Securities or the Trustee all assets held by the Paying Agent for the payment of
principal of, or interest or premium, if any, on, such Series of Securities (whether such assets have been distributed to it by the Company or any other obligor on such Series of Securities), and the Company and the Paying Agent shall notify the
Trustee in writing of any Default by the Company (or any other obligor on such Series of Securities) in making any such payment. The Company at any time may require a Paying Agent to distribute all assets held by it to the Trustee and account for
any assets disbursed, and the Trustee may, at any time during the continuance of any payment default with respect to any Series of Securities, upon written request to a Paying Agent, require such Paying Agent to distribute all assets held by it to
the Trustee and to account for any assets distributed. Upon distribution to the Trustee of all assets that shall have been delivered by the Company to the Paying Agent, the Paying Agent shall have no further liability for such assets. 

 

	2.6.	SECURITYHOLDER LISTS. 

 The Trustee shall preserve in as current a form as is reasonably
practicable the most recent list available to it of the names and addresses of Securityholders of each Series of Securities. If the Trustee is not the Registrar, the Company shall furnish to the Trustee as of each regular record date for the payment
of interest on the Securities of a Series and before each related Interest Payment Date, and at such other times as the Trustee may request in writing, a list in such form and as of such date as the Trustee may reasonably require of the names and
addresses of Securityholders of each Series of Securities. 
  

	2.7.	TRANSFER AND EXCHANGE. 

 When Securities of a Series are presented to the Registrar with a
request to register the transfer thereof, the Registrar shall register the transfer as requested if the requirements of applicable law are met, and when such Securities of a Series are presented to the Registrar with a request to exchange them for
an equal principal amount of other authorized denominations of Securities of the same Series, the Registrar shall make the exchange as requested. To permit transfers and exchanges, upon surrender of any Security for registration of transfer at the
office or agency maintained pursuant to Section 2.4, the Company shall execute and the Trustee shall authenticate Securities at the Registrar’s request. 

If Securities are issued as Global Securities, the provisions of Section 2.15 shall apply. 

  
 9 

 All Securities issued upon any registration of transfer or exchange of Securities shall be the
valid obligations of the Company, evidencing the same debt, and entitled to the same benefits under this Indenture, as the Securities surrendered upon such registration of transfer or exchange. 

Every Security presented or surrendered for registration of transfer or for exchange shall (if so required by the Company or the Registrar or
a co-registrar) be duly endorsed, or be accompanied by a written instrument of transfer in form satisfactory to the Company and the Registrar or a co-registrar, duly executed by the Holder thereof or his attorney duly authorized in writing. 

Any exchange or transfer shall be without charge, except that the Company may require payment by the Holder of a sum sufficient to cover any
tax or other governmental charge that may be imposed in relation to a transfer or exchange, but this provision shall not apply to any exchange pursuant to Section 2.11, 3.6 or 8.5. The Trustee shall not be required to register transfers of
Securities of any Series, or to exchange Securities of any Series, for a period of 15 days before the record date for selection for redemption of such Securities. The Trustee shall not be required to exchange or register transfers of Securities of
any Series called or being called for redemption in whole or in part, except the unredeemed portion of such Security being redeemed in part. 
  

	2.8.	REPLACEMENT SECURITIES. 

 If a mutilated Security is surrendered to the Trustee, or if the
Holder of a Security presents evidence to the satisfaction of the Company and the Trustee that the Security has been lost, destroyed or wrongfully taken, the Company shall issue and the Trustee shall authenticate a replacement Security of the same
Series and of like tenor and principal amount and bearing a number not contemporaneously outstanding. An indemnity bond may be required by the Company or the Trustee that is sufficient in the reasonable judgment of the Company or the Trustee, as the
case may be, to protect the Company, the Trustee or any Agent from any loss which any of them may suffer if a Security is replaced. The Company may charge such Holder for the Company’s out-of-pocket expenses in replacing a Security, including
the fees and expenses of the Trustee. Every replacement Security shall constitute an original additional obligation of the Company, whether or not the destroyed, lost or stolen Security shall be at any time enforceable by anyone, and shall be
entitled to all the benefits of this Indenture equally and proportionately with any and all other Securities of that Series duly issued hereunder. 
  

	2.9.	OUTSTANDING SECURITIES. 

 Securities outstanding at any time are all Securities authenticated by
the Trustee, except for those canceled by it, those delivered to it for cancellation and those described in this Section 2.9 as not outstanding. 

If a Security is replaced pursuant to Section 2.8 (other than a mutilated Security surrendered for replacement), it ceases to be
outstanding until the Company and the Trustee receive proof satisfactory to each of them that the replaced Security is held by a bona fide purchaser. A mutilated Security ceases to be outstanding upon surrender of such Security and replacement
thereof pursuant to Section 2.8. 
 If a Paying Agent holds on a Redemption Date or the Stated Maturity money sufficient to pay the
principal of, premium, if any, and accrued interest on, Securities payable on that date, and is not prohibited from paying such money to the Holders thereof pursuant to the terms of this Indenture (PROVIDED, that if such Securities are to be
redeemed, notice of such redemption has been duly given pursuant to this Indenture or provision therefor satisfactory to the Trustee has been made), then on and after that date such Securities cease to be outstanding and interest on them ceases to
accrue. 
 A Security does not cease to be outstanding solely because the Company or an Affiliate holds the Security. 

  
 10 

	2.10.	WHEN TREASURY SECURITIES DISREGARDED; DETERMINATION OF HOLDERS’ ACTION. 

 In determining
whether the Holders of the required aggregate principal amount of the Securities of any Series have concurred in any direction, waiver or consent, the Securities of any Series owned by the Company or any other obligor on such Securities, or by any
Affiliate of any of them, shall be disregarded, except that for the purposes of determining whether the Trustee shall be protected in relying on any such direction, waiver or consent, only Securities of such Series which the Trustee actually knows
are so owned shall be so disregarded. Securities of such Series so owned which have been pledged in good faith shall not be disregarded if the pledgee establishes to the satisfaction of the Trustee the pledgee’s right so to act with respect to
the Securities of such Series and that the pledgee is not the Company or any other obligor on the Securities of such Series, or an Affiliate of any of them. 
  

	2.11.	TEMPORARY SECURITIES. 

 Until definitive Securities are ready for delivery, the Company may
prepare and execute, and the Trustee shall authenticate, temporary Securities. Temporary Securities shall be substantially in the form, and shall carry all rights, of definitive Securities, but may have variations that the Company considers
appropriate for temporary Securities. Without unreasonable delay, the Company shall prepare and execute, and the Trustee shall authenticate, definitive Securities in exchange for temporary Securities without charge to the Holder. 

 

	2.12.	CANCELLATION. 

 All Securities surrendered for payment, redemption or registration of transfer
or exchange, or for credit against any sinking fund payment, shall, if surrendered to any Person other than the Trustee, be delivered to the Trustee for cancellation. The Company may at any time deliver to the Trustee for cancellation any Securities
previously authenticated and delivered hereunder which the Company may have acquired in any manner whatsoever, and may deliver to the Trustee (or to any other Person for delivery to the Trustee) for cancellation any Securities previously
authenticated hereunder which the Company has not issued and sold. The Registrar and the Paying Agent shall forward to the Trustee any Securities surrendered to them for transfer, exchange or payment. The Trustee or, at the direction of the Trustee,
the Registrar or the Paying Agent, and no one else, shall cancel, and at the written request of the Company shall dispose of, all Securities surrendered for transfer, exchange, payment or cancellation. If the Company shall acquire any of the
Securities, such acquisition shall not operate as a redemption or satisfaction of the Indebtedness represented by such Securities unless and until the same are surrendered to the Trustee for cancellation pursuant to this Section 2.12. No
Securities shall be authenticated in lieu of or in exchange for any Securities cancelled as provided in this Section 2.12, except as expressly permitted by this Indenture. 

 

	2.13.	PAYMENT OF INTEREST; DEFAULTED INTEREST; COMPUTATION OF INTEREST. 

 Except as otherwise provided
as contemplated by Section 2.2 with respect to any Series of Securities, interest on any Security which is payable, and is punctually paid or duly provided for, on any Interest Payment Date shall be paid to the Person in whose name that
Security is registered at the close of business on the regular record date for such interest, as provided in the Board Resolution, supplemental indenture hereto or Officers’ Certificate establishing the terms of such Series. 

If the Company defaults in a payment of interest on the Securities, it shall pay the defaulted amounts, plus any interest payable on defaulted
amounts pursuant to Section 4.1, to the Persons who are Securityholders on a subsequent special record date, which date shall be the 15th day next preceding the date fixed by the Company for the payment of defaulted interest, or the next
succeeding Business Day if such date is not a Business Day. At least 15 days before the special record date, the Company shall mail or cause to be mailed to each Securityholder, with a copy to the Trustee, a notice that states the special record
date, the payment date and the amount of defaulted interest, and interest payable on such defaulted interest, if any, to be paid. 
 Except
as otherwise specified as contemplated by Section 2.2 for Securities of any Series, interest on the Securities of each Series shall be computed on the basis of a 360-day year of twelve 30-day months. 

  
 11 

	2.14.	CUSIP NUMBER. 

 The Company in issuing the Securities may use one or more “CUSIP”
numbers, and, if the Company does so, the Trustee shall use the CUSIP number(s) in notices of redemption or exchange as a convenience to Holders, PROVIDED, that any such notice may state that no representation is made as to the correctness or
accuracy of the CUSIP number(s) printed in the notice or on the Securities, and that reliance may be placed only on the other identification numbers printed on the Securities, and that any such redemption or exchange shall not be affected by any
defect in or omission of any such numbers. 
  

	2.15.	PROVISIONS FOR GLOBAL SECURITIES. 

 (a) A Board Resolution, a supplemental indenture hereto or
an Officers’ Certificate shall establish whether the Securities of a Series shall be issued in whole or in part in the form of one or more Global Securities, and the Depository for such Global Securities or Securities. 

(b) Notwithstanding any provisions to the contrary contained in Section 2.7 and in addition thereto, if, and only if the Depository
(i) at any time is unwilling or unable to continue as Depository for such Global Security or ceases to be a clearing agency registered under the Exchange Act and (ii) a successor Depository is not appointed by the Company within 90 days
after the date the Company is so informed in writing or becomes aware of the same, the Company promptly will execute and deliver to the Trustee definitive Securities, and the Trustee, upon receipt of a Company Request for the authentication and
delivery of such definitive Securities (which the Company will promptly execute and deliver to the Trustee) and an Officers’ Certificate to the effect that such Global Security shall be so exchangeable, will authenticate and deliver definitive
Securities, without charge, registered in such names and in such authorized denominations as the Depository shall direct in writing (pursuant to instructions from its direct and indirect participants or otherwise) in an aggregate principal amount
equal to the principal amount of the Global Security with like tenor and terms. Upon the exchange of a Global Security for definitive Securities, such Global Security shall be canceled by the Trustee. Unless and until it is exchanged in whole or in
part for definitive Securities, as provided in this Section 2.15(b), a Global Security may not be transferred except as a whole by the Depository with respect to such Global Security to a nominee of such Depository, by a nominee of such
Depository to such Depository or another nominee of such Depository or by the Depository or any such nominee to a successor Depository or a nominee of such a successor Depository. 

(c) Any Global Security issued hereunder shall bear a legend in substantially the following form: 

“This Security is a Global Security within the meaning of the Indenture hereinafter referred to, and is registered in the name of the
Depository or a nominee of the Depository. This Security is exchangeable for Securities registered in the name of a Person other than the Depository or its nominee only in the limited circumstances described in the Indenture, and may not be
transferred except as a whole by the Depository to a nominee of the Depository, by a nominee of the Depository to the Depository or another nominee of the Depository or by the Depository or any such nominee to a successor Depository or a nominee of
such a successor Depository.” 
 (d) The Depository, as a Holder, may appoint agents and otherwise authorize participants to give or
take any request, demand, authorization, direction, notice, consent, waiver or other action which a Holder is entitled to give or take under the Indenture. 

(e) Notwithstanding the other provisions of this Indenture, unless otherwise specified as contemplated by Section 2.2, payment of the
principal of, and interest and premium, if any, on, any Global Security shall be made to the Depository or its nominee in its capacity as the Holder thereof. 

(f) Except as provided in Section 2.15(e) above, the Company, the Trustee and any Agent shall treat a Person as the Holder of such
principal amount of outstanding Securities of any Series represented by a Global Security as shall be specified in a written statement of the Depository (which may be in the form of a participants’ list for such Series) with respect to such
Global Security, for purposes of obtaining any consents, declarations, waivers or directions required to be given by the Holders pursuant to this Indenture, PROVIDED, that until the Trustee is so provided with a written statement, it may treat the
Depository or any other Person in whose name a Global Security is registered as the owner of such Global Security for the purpose of receiving payment of the principal of, and any premium and (subject to Section 2.13) any interest on, such
Global Security and for all other purposes whatsoever, and none of the Company, the Trustee or any agent of the Company or the Trustee shall be affected by notice to the contrary. 

  
 12 

	2.16.	PERSONS DEEMED OWNERS. 

 Prior to due presentment of a Security for registration of transfer,
the Company, the Trustee, the Registrar and any agent of the Company, the Registrar or the Trustee may treat the Person in whose name such Security is registered as the owner of such Security for the purpose of receiving payment of the principal of,
and any premium and (subject to Section 2.13) any interest on, such Security and for all other purposes whatsoever, and none of the Company, the Trustee, the Registrar or any agent of the Company, the Trustee or the Registrar shall be affected
by notice to the contrary. 
 ARTICLE 3 

REDEMPTION 
  

	3.1.	NOTICES TO TRUSTEE. 

 The Company may, with respect to any Series of Securities, reserve the
right to redeem and pay the Series of Securities, or may covenant to redeem and pay the Series of Securities or any part thereof, prior to the Stated Maturity thereof at such time and on such terms as provided for in such Securities or the related
Board Resolution, supplemental indenture or Officers’ Certificate. If a Series of Securities is redeemable and the Company elects to redeem all or part of such Series of Securities, it shall notify the Trustee of the Redemption Date and the
principal amount of Securities to be redeemed at least 45 days (unless a shorter notice shall be satisfactory to the Trustee) before the Redemption Date. Any such notice may be canceled at any time prior to notice of such redemption being mailed to
any Holder, and shall thereby be void and of no effect. 
  

	3.2.	SELECTION BY TRUSTEE OF SECURITIES TO BE REDEEMED. 

 Unless otherwise indicated for a particular
Series of Securities by a Board Resolution, a supplemental indenture or an Officers’ Certificate, if fewer than all of the Securities of a Series are to be redeemed, the Trustee shall select the Securities of a Series to be redeemed pro rata,
by lot or by any other method that the Trustee considers fair and appropriate (unless the Company specifically directs the Trustee otherwise) and, if such Securities are listed on any securities exchange, by a method that complies with the
requirements of such exchange. 
 The Trustee shall make the selection from Securities of a Series outstanding and not previously called for
redemption, and shall promptly notify the Company in writing of the Securities selected for redemption and, in the case of any Security selected for partial redemption, the principal amount thereof to be redeemed at least 35 but not more than 60
days before the Redemption Date. Securities of a Series in denominations of $1,000 may be redeemed only in whole. The Trustee may select for redemption portions of the principal of Securities of a Series that have denominations larger than $1,000.
Securities of a Series and portions of them it selects shall be in amounts of $1,000 or, with respect to Securities of any Series issuable in other denominations pursuant to Section 2.2(10), the minimum principal denomination for each Series
and integral multiples thereof. Provisions of this Indenture that apply to Securities called for redemption also apply to portions of Securities called for redemption. 
  

	3.3.	NOTICE OF REDEMPTION. 

 Unless otherwise indicated for a particular Series by Board Resolution,
a supplemental indenture hereto or an Officers’ Certificate, at least 30 days, and no more than 60 days, before a Redemption Date, the Company shall mail, or cause to be mailed, a notice of redemption by first-class mail to each Holder of
Securities to be redeemed at his or her last address as the same appears on the registry books maintained by the Registrar. The notice shall identify the Securities to be redeemed and shall state: 

(1) the Redemption Date; 

  
 13 

 (2) the redemption price, and that such redemption price shall become due and payable on the
Redemption Date; 
 (3) if any Security of a Series is being redeemed in part, the portion of the principal amount of such Security of a
Series to be redeemed and that, after the Redemption Date and upon surrender of such Security of a Series, a new Security or Securities in principal amount equal to the unredeemed portion will be issued; 

(4) the name and address of the Paying Agent; 

(5) that Securities of a Series called for redemption must be surrendered to the Paying Agent to collect the redemption price, and the place
or places where each such Security is to be surrendered for such payment; 
 (6) that, unless the Company defaults in making the redemption
payment, interest on the Securities of a Series called for redemption ceases to accrue on the Redemption Date, and the only remaining right of the Holders of such Securities is to receive payment of the redemption price upon surrender to the Paying
Agent of the Securities redeemed; 
 (7) if fewer than all of the Securities of a Series are to be redeemed, the identification of the
particular Securities of a Series (or portion thereof) to be redeemed, as well as the aggregate principal amount of Securities of a Series to be redeemed and the aggregate principal amount of Securities of a Series to be outstanding after such
partial redemption. 
 (8) the CUSIP number, if any, printed on the Securities being redeemed; and 

(9) that no representation is made as to the correctness or accuracy of the CUSIP number, if any, listed in such notice or printed on the
Securities. 
 At the Company’s request, the Trustee shall give the notice of redemption in the Company’s name and at the
Company’s sole expense. 
  

	3.4.	EFFECT OF NOTICE OF REDEMPTION. 

 Once the notice of redemption described in Section 3.3 is
mailed, Securities of a Series called for redemption become due and payable on the Redemption Date and at the redemption price, plus interest, if any, accrued to the Redemption Date. Upon surrender to the Trustee or Paying Agent, such Securities of
a Series shall be paid at the redemption price, plus accrued interest, if any, to the Redemption Date; PROVIDED, that if the Redemption Date is after a regular interest payment record date and on or prior to the next Interest Payment Date, the
accrued interest shall be payable to the Holder of the redeemed Securities registered on the relevant record date, as specified by the Company in the notice to the Trustee pursuant to Section 3.1. 

 

	3.5.	DEPOSIT OF REDEMPTION PRICE. 

 On or prior to the Redemption Date (but no later than 11:00 A.M.
Eastern Time on such date), the Company shall deposit with the Paying Agent money sufficient to pay the redemption price of and accrued interest, if any, on all Securities to be redeemed on that date other than Securities or portions thereof called
for redemption on that date which have been delivered by the Company to the Trustee for cancellation. 
 On and after any Redemption Date,
if money sufficient to pay the redemption price of, and accrued interest on, Securities called for redemption shall have been made available in accordance with the preceding paragraph and the Company and the Paying Agent are not prohibited from
paying such moneys to Holders, the Securities called for redemption will cease to accrue interest and the only right of the Holders of such Securities will be to receive payment of the redemption price of and, subject to the proviso in
Section 3.4, accrued and unpaid interest on such Securities to the Redemption Date. If any Security called for redemption shall not be so paid, interest will be paid, from the Redemption Date until such redemption payment is made, on the unpaid
principal of the Security and any interest or premium, if any, not paid on such unpaid principal, in each case, at the rate and in the manner provided in the Securities. 

  
 14 

	3.6.	SECURITIES REDEEMED IN PART. 

 Upon surrender of a Security of a Series that is redeemed in
part, the Company shall execute, and the Trustee shall authenticate, for a Holder a new Security of the same Series equal in principal amount to the unredeemed portion of the Security surrendered. 

ARTICLE 4 
 COVENANTS

  

	4.1.	PAYMENT OF SECURITIES. 

 The Company shall pay the principal of, and interest and premium, if
any, on, each Series of Securities on the dates and in the manner provided in such Securities and this Indenture. 
 An installment of
principal or interest shall be considered paid on the date it is due if the Trustee or Paying Agent holds on that date money designated for and sufficient to pay such installment and is not prohibited from paying such money to the Holders pursuant
to the terms of this Indenture or otherwise. 
 The Company shall pay interest on overdue principal, and overdue interest, to the extent
lawful, at the rate specified in the Series of Securities. 
  

	4.2.	SEC REPORTS. 

 The Company will deliver to the Trustee within 15 days after the filing of the
same with the SEC, copies of the quarterly and annual reports and of the information, documents and other reports, if any, which the Company is required to file with the SEC pursuant to Section 13 or 15(d) of the Exchange Act; PROVIDED,
HOWEVER, that each such report or document will be deemed to be so delivered to the Trustee if the Company files such report or document with the SEC through the SEC’s EDGAR database no later than the time such report or document is required to
be filed with the SEC pursuant to the Exchange Act. Notwithstanding that the Company may not be subject to the reporting requirements of Section 13 or 15(d) of the Exchange Act, the Company will file with the SEC, to the extent permitted, and
provide the Trustee with, such quarterly and annual reports and such information, documents and other reports specified in Sections 13 and 15(d) of the Exchange Act. The Company will also comply with the other provisions of TIA Section 314(a).

  

	4.3.	WAIVER OF STAY, EXTENSION OR USURY LAWS. 

 The Company covenants (to the extent that it may
lawfully do so) that it will not at any time insist upon, or plead (as a defense or otherwise) or in any manner whatsoever claim or take the benefit or advantage of, any stay, extension, usury or other law which would prohibit or forgive the Company
from paying all or any portion of the principal of, and/or interest and premium, if any, on, the Securities as contemplated herein, wherever enacted, now or at any time hereafter in force, or which may affect the covenants or the performance of this
Indenture; and the Company hereby expressly waives (to the extent that they may lawfully do so) all benefit or advantage of any such law, and covenants that it will not hinder, delay or impede the execution of any power herein granted to the
Trustee, but will suffer and permit the execution of every such power as though no such law had been enacted. 
  

	4.4.	COMPLIANCE CERTIFICATE. 

 (a) The Company shall deliver to the Trustee, within 120 days after
the end of each fiscal year of the Company, an Officers’ Certificate which complies with TIA Section 314(a)(4) stating that a review of the activities of the Company and its Subsidiaries during such fiscal year has been made under the
supervision of the signing Officers with a view to determining whether the Company has kept, observed, performed and fulfilled its obligations under this Indenture, and further stating, as to each such Officer signing such certificate, that to the
best of his or her knowledge the Company has kept, observed, 

  
 15 

 
performed and fulfilled each and every covenant contained in this Indenture and that there is no default in the performance or observance of any of the terms, provisions and conditions hereof
(or, if a Default or Event of Default shall have occurred, describing all such Defaults or Events of Default of which he or she may have knowledge and what action the Company is taking or proposes to take with respect thereto) and that to the best
of his or her knowledge no event has occurred and remains in existence by reason of which payments on account of the principal of, or interest or premium, if any, on, the Securities is prohibited, or if such event has occurred, a description of the
event and what action the Company is taking or proposes to take with respect thereto. 
 (b) (i) If any Default or Event of Default has
occurred and is continuing or (ii) if any Holder seeks to exercise any remedy hereunder with respect to a claimed Default under this Indenture or the Securities, within five Business Days after the Company becoming aware of such occurrence the
Company shall deliver to the Trustee an Officers’ Certificate specifying such event, notice or other action and what action the Company is taking or proposes to take with respect thereto. 

 

	4.5.	CORPORATE EXISTENCE. 

 Subject to Article 5, the Company shall do or cause to be done all things
necessary to preserve and keep in full force and effect its corporate existence, in accordance with the organizational documents (as the same may be amended from time to time) of the Company and the rights (charter and statutory), licenses and
franchises of the Company; PROVIDED, HOWEVER, that the Company shall not be required to preserve any such right, license or franchise, or its corporate existence, if the Board of Directors shall determine that the preservation thereof is no longer
desirable in the conduct of the business of the Company and that the loss thereof is not adverse in any material respect to the Holders. 

ARTICLE 5 
 SUCCESSOR
CORPORATION 
  

	5.1.	LIMITATION ON CONSOLIDATION, MERGER AND SALE OF ASSETS. 

 (a) The Company will not, in any
transaction or series of transactions, merge or consolidate with or into, or sell, assign, convey, transfer, lease or otherwise dispose of all or substantially all of its properties and assets (as an entirety or substantially as an entirety in one
transaction or a series of related transactions), to any Person or Persons, unless at the time of and after giving effect thereto (i) either (A) if the transaction or series of transactions is a merger or consolidation, the Company shall
be the surviving Person of such merger or consolidation, or (B) the Person formed by such consolidation or into which the Company is merged or to which the properties and assets of the Company are transferred (any such surviving Person or
transferee Person being the “Surviving Entity”) shall be a corporation organized and existing under the laws of the United States of America, any state thereof or the District of Columbia, or a corporation or comparable legal entity
organized under the laws of a foreign jurisdiction and shall expressly assume by a supplemental indenture executed and delivered to the Trustee, in form reasonably satisfactory to the Trustee, all of the obligations of the Company (including,
without limitation, the obligation to pay the principal of, and premium and interest, if any, on, the Securities and the performance of the other covenants) under the Securities of each Series and this Indenture, and in each case, this Indenture
shall remain in full force and effect; and (ii) immediately before and immediately after giving effect to such transaction or series of transactions on a pro forma basis (including, without limitation, any Indebtedness incurred or anticipated
to be incurred in connection with or in respect of such transaction or series of transactions), no Default or Event of Default shall have occurred and be continuing. 

(b) In connection with any consolidation, merger or transfer of assets contemplated by this Section 5.1, the Company shall deliver, or
cause to be delivered, to the Trustee, in form and substance reasonably satisfactory to the Trustee, an Officers’ Certificate and an Opinion of Counsel, each stating that such consolidation, merger or transfer, and the supplemental indenture in
respect thereto, comply with this Section 5.1, and that all conditions precedent herein provided for relating to such transaction or transactions have been complied with. 

  
 16 

	5.2.	SUCCESSOR PERSON SUBSTITUTED. 

 Upon any consolidation, merger or transfer of all or
substantially all of the assets of the Company in accordance with Section 5.1 above, the successor corporation formed by such consolidation, or into which the Company is merged or to which such transfer is made, shall succeed to, and be
substituted for, and may exercise every right and power of, the Company under this Indenture with the same effect as if such successor corporation had been named as the Company herein, and thereafter (except with respect to any such transfer which
is a lease) the predecessor corporation shall be relieved of all obligations and covenants under this Indenture and the Securities. 

ARTICLE 6 
 DEFAULTS AND
REMEDIES 
  

	6.1.	EVENTS OF DEFAULT. 

 “Events of Default,” wherever used herein with respect to
Securities of any Series, means any one of the following events, unless in the establishing Board Resolution, supplemental indenture or Officers’ Certificate, it is provided that such Series shall not have the benefit of said Event of Default:

 (1) there is a default in the payment of any principal of, or premium, if any, on, the Securities when the same becomes due and payable
at Maturity, upon acceleration, redemption or otherwise; 
 (2) there is a default in the payment of any interest on any Security of a
Series when the same becomes due and payable, and the Default continues for a period of 30 days; 
 (3) the Company defaults in the
observance or performance of any other covenant in the Securities of a Series or in this Indenture for 60 days after written notice from the Trustee or the Holders of not less than 25% in the aggregate principal amount of the Securities of such
Series then outstanding, which notice must specify the Default, demand that it be remedied and state that the notice is a “Notice of Default”; 

(4) the Company or any Significant Subsidiary pursuant to or within the meaning of any Bankruptcy Law: 

(A) commences a voluntary case, 

(B) consents to the entry of an order for relief against it in an involuntary case, 

(C) consents to the appointment of a Custodian of it or for all or substantially all of its property, 

(D) makes a general assignment for the benefit of its creditors, or 

(E) generally is not paying its debts as they become due; 

(5) a court of competent jurisdiction enters an order or decree under any Bankruptcy Law that: 

(A) is for relief against the Company or any Significant Subsidiary in an involuntary case; 

(B) appoints a Custodian of the Company or any Significant Subsidiary, or for all or substantially all of the property of the
Company or any Significant Subsidiary; or 
 (C) orders the liquidation of the Company or any Significant Subsidiary, and the
order or decree remains unstayed and in effect for 90 consecutive days; or 
 (6) any other Event of Default provided with respect to
Securities of that Series, which is specified in a Board Resolution, a supplemental indenture hereto or an Officers’ Certificate, in accordance with Section 2.2(19). 

  
 17 

 The term “Bankruptcy Law” means Title 11, U.S. Code, or any similar federal or state
law for the relief of debtors. The term “Custodian” means any receiver, trustee, assignee, liquidator or similar official under any Bankruptcy Law. 

The Trustee may withhold notice of any Default (except in the payment of the principal of, or interest or premium, if any, on, the Securities)
to the Holders of the Securities of any Series in accordance with Section 7.5. When a Default is cured, it ceases to exist. 
  

	6.2.	ACCELERATION. 

 If an Event of Default with respect to Securities of any Series at the time
outstanding (other than an Event of Default arising under Section 6.1(4) or (5)) occurs and is continuing, the Trustee by written notice to the Company, or the Holders of not less than 25% in aggregate principal amount of the Securities of
that Series then outstanding by written notice to the Company and the Trustee, may declare that the entire principal amount of all the Securities of that Series then outstanding plus accrued and unpaid interest to the date of acceleration are
immediately due and payable, in which case such amounts shall become immediately due and payable; PROVIDED, HOWEVER, that after such acceleration but before a judgment or decree based on such acceleration is obtained by the Trustee, the Holders of a
majority in aggregate principal amount of the outstanding Securities of that Series may rescind and annul such acceleration and its consequences if (i) all existing Events of Default, other than the nonpayment of accelerated principal, interest
or premium, if any, that has become due solely because of the acceleration, have been cured or waived, (ii) to the extent the payment of such interest is lawful, interest on overdue installments of interest and overdue principal, which has
become due otherwise than by such declaration of acceleration, has been paid and (iii) the rescission would not conflict with any judgment or decree. No such rescission shall affect any subsequent Default or impair any right consequent thereto.
In case an Event of Default specified in Section 6.1(4) or (5) with respect to the Company occurs, such principal, premium, if any, and interest amount with respect to all of the Securities of that Series shall be due and payable
immediately without any declaration or other act on the part of the Trustee or the Holders of the Securities of that Series. 
  

	6.3.	REMEDIES. 

 If an Event of Default with respect to Securities of any Series at the time
outstanding occurs and is continuing, the Trustee may pursue any available remedy by proceeding at law or in equity to collect the payment of the principal of, or interest and premium, if any, on, the Securities of that Series, or to enforce the
performance of any provision of the Securities of that Series or this Indenture. 
 The Trustee may maintain a proceeding even if it does
not possess any of the Securities of that Series or does not produce any of them in the proceeding. A delay or omission by the Trustee or any Securityholder in exercising any right or remedy accruing upon an Event of Default shall not impair the
right or remedy or constitute a waiver of or acquiescence in the Event of Default. No remedy is exclusive of any other remedy. All available remedies are cumulative to the extent permitted by law. 

 

	6.4.	WAIVER OF PAST DEFAULTS AND EVENTS OF DEFAULT. 

 Subject to Sections 6.2, 6.7 and 8.2, the
Holders of a majority in principal amount of the Securities of any Series then outstanding have the right to waive any existing Default or Event of Default with respect to such Series or compliance with any provision of this Indenture (with respect
to such Series) or the Securities of such Series. Upon any such waiver, such Default with respect to such Series shall cease to exist, and any Event of Default with respect to such Series arising therefrom shall be deemed to have been cured for
every purpose of this Indenture; but no such waiver shall extend to any subsequent or other Default or Event of Default or impair any right consequent thereto. This Section 6.4 shall be in lieu of TIA Section 316(a)(1)(B), and TIA
Section 316(a)(1)(B) is hereby expressly excluded from this Indenture and Section as permitted by the TIA. 
  

	6.5.	CONTROL BY MAJORITY. 

 Subject to Sections 6.2, 6.7 and 8.2, the Holders of a majority in
principal amount of the Securities of any Series then outstanding may direct the time, method and place of conducting any proceeding for any 

  
 18 

 
remedy available to the Trustee or exercising any trust or power conferred on the Trustee by this Indenture with respect to such Series. The Trustee, however, may refuse to follow any direction
that conflicts with law or this Indenture, or that the Trustee determines may be unduly prejudicial to the rights of another Securityholder, or that may involve the Trustee in personal liability; PROVIDED, that the Trustee may take any other action
deemed proper by the Trustee which is not inconsistent with such direction. This Section 6.5 shall be in lieu of TIA Section 316(a)(1)(A), and TIA Section 316(a)(1)(A) is hereby expressly excluded from this Indenture and Section as
permitted by the TIA. 
  

	6.6.	LIMITATION ON SUITS. 

 Subject to Section 6.7, a Securityholder may not institute any
proceeding or pursue any remedy with respect to this Indenture or the Securities of a Series unless: 
 (1) the Holder gives to the Trustee
written notice of a continuing Event of Default with respect to the Securities of that Series; 
 (2) the Holders of at least 25% in
aggregate principal amount of the Securities of such Series then outstanding make a written request to the Trustee to pursue the remedy; 

(3) such Holder or Holders offer to the Trustee indemnity reasonably satisfactory to the Trustee against any loss, liability or expense to be
incurred in compliance with such request; 
 (4) the Trustee does not comply with the request within 60 days after receipt of the request
and the offer of indemnity; and 
 (5) no direction inconsistent with such written request has been given to the Trustee during such 60-day
period by the Holders of a majority in aggregate principal amount of the Securities of such Series then outstanding. 
 A Securityholder may
not use this Indenture to prejudice the rights of another Securityholder, or to obtain a preference or priority over another Securityholder. 
  

	6.7.	RIGHTS OF HOLDERS TO RECEIVE PAYMENT. 

 Notwithstanding any other provision of this Indenture,
the right of any Holder of a Security of a Series to receive payment of the principal of, and interest and premium, if any, on, the Security of such Series on or after the respective due dates expressed in the Security of such Series, or to bring
suit for the enforcement of any such payment on or after such respective dates, is absolute and unconditional, and shall not be impaired or affected without the consent of the Holder. 

 

	6.8.	COLLECTION SUIT BY TRUSTEE. 

 If an Event of Default in payment of principal, interest or
premium, if any, specified in Section 6.1(1) or (2) with respect to Securities of any Series at the time outstanding occurs and is continuing, the Trustee may recover judgment in its own name and as trustee of an express trust against the
Company (or any other obligor on the Securities of that Series) for the whole amount of unpaid principal and premium, if any, and accrued interest remaining unpaid, together with interest on overdue principal and premium, if any, and, to the extent
that payment of such interest is lawful, interest on overdue installments of interest, in each case at the rate then borne by the Securities of that Series, and such further amounts as shall be sufficient to cover the costs and expenses of
collection, including the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, as set forth in Section 7.7. 
  

	6.9.	TRUSTEE MAY FILE PROOFS OF CLAIM. 

 The Trustee may file such proofs of claim and other papers
or documents, and take other actions (including sitting on a committee of creditors), as may be necessary or advisable in order to have the claims of the Trustee (including any claim for the reasonable compensation, expenses, disbursements and
advances of the Trustee, its agents and counsel) and the Securityholders allowed in any judicial 

  
 19 

 
proceedings relative to the Company (or any other obligor on the Securities), any of their respective creditors or any of their respective property, and the Trustee shall be entitled and
empowered to collect and receive any monies or other property payable or deliverable on any such claims, and to distribute the same after deduction of its charges and expenses to the extent that any such charges and expenses are not paid out of the
estate in any such proceedings, and any custodian in any such judicial proceeding is hereby authorized by each Securityholder to make such payments to the Trustee, and in the event that the Trustee shall consent to the making of such payments
directly to the Securityholders, to pay to the Trustee any amount due to it for the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, and any other amounts due the Trustee under Section 7.7.

 Nothing herein contained shall be deemed to authorize the Trustee to authorize or consent to, or accept or adopt on behalf of any
Securityholder, any plan of reorganization, arrangement, adjustment or composition affecting the Securities of a Series or the rights of any Holder thereof, or to authorize the Trustee to vote in respect of the claim of any Securityholder in any
such proceedings. 
  

	6.10.	PRIORITIES. 

 If the Trustee collects any money pursuant to this Article 6, it shall pay out the
money in the following order: 
 FIRST: to the Trustee for amounts due under Section 7.7; 

SECOND: to Securityholders for amounts then due and unpaid for the principal of, and interest and premium, if any, on, the Securities in
respect of which, or for the benefit of which, such money has been collected, ratably, without preference or priority of any kind, according to the amounts due and payable on such Securities; for principal and any premium and interest, respectively;
and 
 THIRD: to the Company. 

The Trustee may fix a record date and payment date for any payment to Securityholders pursuant to this Section 6.10. At least 15 days
before such record date, the Trustee shall mail to each Securityholder a notice that states the record date, the payment date and amount to be paid. 
  

	6.11.	UNDERTAKING FOR COSTS. 

 In any suit for the enforcement of any right or remedy under this
Indenture, or in any suit against the Trustee for any action taken or omitted by it as Trustee, a court in its discretion may require the filing by any party litigant in the suit of an undertaking to pay the costs of the suit, and the court in its
discretion may assess reasonable costs, including reasonable attorneys’ fees, against any party litigant in the suit, having due regard to the merits and good faith of the claims or defenses made by the party litigant. This Section 6.11
does not apply to a suit by the Trustee, a suit by a Holder pursuant to Section 6.7 or a suit by Holders of more than 10% in principal amount of the Securities of a Series then outstanding. 

ARTICLE 7 
 TRUSTEE

  

	7.1.	DUTIES OF TRUSTEE. 

 (a) If an Event of Default has occurred and is continuing, the Trustee
shall exercise such of the rights and powers vested in it by this Indenture and use the same degree of care and skill in their exercise as a prudent Person would exercise or use under the same circumstances in the conduct of his own affairs. 

(b) Except during the continuance of an Event of Default: 

(1) The Trustee need perform only those duties that are specifically set forth in this Indenture, and no covenants or obligations shall be
implied in this Indenture against the Trustee. 
 (2) In the absence of bad faith on its part, the Trustee may conclusively rely, as to the
truth of the statements and the correctness of the opinions expressed therein, upon certificates or opinions furnished to the Trustee and conforming to the requirements of this Indenture, but, in the case of any such certificates or opinions which
by any provision hereof are specifically required to be furnished to the Trustee, the Trustee shall be under a duty to examine the same to determine whether or not they conform to the requirements of this Indenture. 

  
 20 

 (c) The Trustee may not be relieved from liability for its own negligent action, its own
negligent failure to act or its own willful misconduct, except that: 
 (1) This paragraph does not limit the effect of paragraph
(b) of this Section 7.1. 
 (2) The Trustee shall not be liable for any error of judgment made in good faith by a Responsible
Officer, unless it is proved that the Trustee was negligent in ascertaining the pertinent facts. 
 (3) The Trustee shall not be liable with
respect to any action it takes or omits to take in good faith in accordance with a direction received by it pursuant to Sections 6.2 and 6.5. 

(d) No provision of this Indenture shall require the Trustee to expend or risk its own funds, or otherwise incur any financial liability, in
the performance of any of its rights or powers if it shall have reasonable grounds for believing that repayment of such funds or adequate indemnity satisfactory to it against such risk or liability is not reasonably assured to it. 

(e) Whether or not therein expressly so provided, paragraphs (a), (b), (c) and (d) of this Section 7.1 shall govern every
provision of this Indenture that in any way relates to the Trustee. 
 (f) The Trustee and Paying Agent shall not be liable for interest on
any money received by either of them, except as the Trustee and Paying Agent may agree in writing with the Company. Money held in trust by the Trustee need not be segregated from other funds except to the extent required by the law. 

(g) The Paying Agent, the Registrar and any authenticating agent shall be entitled to the protections, immunities and standard of care set
forth in paragraphs (a), (b), (c), (d) and (f) of this Section 7.1 and in Section 7.2 with respect to the Trustee. 
  

	7.2.	RIGHTS OF TRUSTEE. 

 (a) Subject to Section 7.1: 

(1) The Trustee may rely on, and shall be protected in acting or refraining from acting upon, any document reasonably believed by it to be
genuine and to have been signed or presented by the proper Person. The Trustee need not investigate any fact or matter stated in the document. 

(2) Before the Trustee acts or refrains from acting, it may require an Officers’ Certificate or an Opinion of Counsel, or both, which
shall conform to the provisions of Section 10.5. The Trustee shall be protected and shall not be liable for any action it takes or omits to take in good faith in reliance on such certificate or opinion. 

(3) The Trustee may act through agents and attorneys, and shall not be responsible for the misconduct or negligence of any agent appointed by
it with due care. 
 (4) The Trustee shall not be liable for any action it takes or omits to take in good faith which it reasonably believes
to be authorized or within its rights or powers. 
 (5) The Trustee may consult with counsel reasonably acceptable to the Trustee, which may
be counsel to the Company, and the advice or opinion of such counsel as to matters of law shall be full and complete authorization and protection from liability in respect of any action taken, omitted or suffered by it hereunder in good faith and in
accordance with the advice or opinion of such counsel. 

  
 21 

 (6) The Trustee shall be under no obligation to exercise any of the rights or powers vested in it
by this Indenture at the request, order or direction of any of the Holders pursuant to the provisions of this Indenture, unless such Holders shall have offered to the Trustee reasonable security or indemnity against the costs, expenses and
liabilities which may be incurred therein or thereby. 
 (7) The Trustee shall not be deemed to have knowledge of any fact or matter
(including, without limitation, a Default or Event of Default) unless such fact or matter is known to a Responsible Officer of the Trustee. 

(8) Unless otherwise expressly provided herein or in the Securities of a Series or the related Board Resolution, supplemental indenture or
Officers’ Certificate, the Trustee shall not have any responsibility with respect to reports, notices, certificates or other documents filed with it hereunder, except to make them available for inspection, at reasonable times, by
Securityholders, it being understood that delivery of such reports, information and documents to the Trustee is for informational purposes only and the Trustee’s receipt of such shall not constitute constructive notice of any information
contained therein or determinable from information contained therein, including the Company’s compliance with any of its covenants hereunder (except as set forth in Section 4.4). 

 

	7.3.	INDIVIDUAL RIGHTS OF TRUSTEE. 

 The Trustee in its individual or any other capacity may become
the owner or pledgee of Securities, and may make loans to, accept deposits from, perform services for or otherwise deal with the Company, or any Affiliate thereof, with the same rights it would have if it were not Trustee. Any Agent may do the same
with like rights. The Trustee, however, shall be subject to Sections 7.10 and 7.11. 
  

	7.4.	TRUSTEE’S DISCLAIMER. 

 The Trustee makes no representation as to the validity or adequacy
of this Indenture or the Securities (except that the Trustee represents that it is duly authorized to execute and deliver this Indenture and authenticate the Securities and perform its obligations hereunder), and the Trustee shall not be accountable
for the Company’s use of the proceeds from the sale of Securities or any money paid to the Company pursuant to the terms of this Indenture, and the Trustee shall not be responsible for any statement in the Securities other than its certificates
of authentication. 
  

	7.5.	NOTICE OF DEFAULT. 

 If a Default or an Event of Default occurs and is continuing with respect
to the Securities of any Series, and if it is known to the Trustee, the Trustee shall mail to each Securityholder of the Securities of that Series notice of the Default or the Event of Default, as the case may be, within 90 days after it occurs or,
if later, after a Responsible Officer of the Trustee has knowledge of such Default or Event of Default (except if such Default or Event of Default has been validly cured or waived before the giving of such notice). Except in the case of a Default or
an Event of Default in payment of the principal of, or interest or premium, if any, on, any Security of any Series, the Trustee may withhold the notice if and so long as the Board of Directors of the Trustee, the executive committee or any trust
committee of such board and/or its Responsible Officers in good faith determine(s) that withholding the notice is in the interests of the Securityholders of that Series. 
  

	7.6.	REPORTS BY TRUSTEE TO HOLDERS. 

 If and to the extent required by the TIA, within 60 days after
April 1 of each year, commencing the April 1 following the date of this Indenture, the Trustee shall mail to each Securityholder a brief report dated as of such April 1 that complies with TIA Section 313(a). The Trustee also
shall comply with TIA Sections 313(b) and 313(c). 
 A copy of each report at the time of its mailing to Securityholders shall be filed with
the SEC and any stock exchange on which the Securities of that Series are listed. The Company shall promptly notify the Trustee when the Securities of any Series are listed on any stock exchange or any delisting thereof, and the Trustee shall comply
with TIA Section 313(d). 

  
 22 

	7.7.	COMPENSATION AND INDEMNITY. 

 The Company shall pay to the Trustee from time to time reasonable
compensation for its services. The Trustee’s compensation shall not be limited by any provision of law on compensation of a trustee of an express trust. The Company shall reimburse the Trustee within 45 days after receipt of request for all
reasonable out-of-pocket disbursements and expenses incurred or made by it in connection with its duties under this Indenture, including the reasonable compensation, disbursements and expenses of the Trustee’s agents and counsel. 

The Company shall indemnify the Trustee for, and hold it harmless against, any and all loss or liability incurred by it in connection with the
acceptance or performance of its duties under this Indenture including the reasonable costs and expenses of defending itself against any claim or liability in connection with the exercise or performance of any of its powers or duties hereunder. The
Trustee shall notify the Company promptly of any claim asserted against the Trustee for which it may seek indemnity. 
 The failure by the
Trustee to so notify the Company shall not however relieve the Company of its obligations. Notwithstanding the foregoing, the Company need not reimburse the Trustee for any expense or indemnify it against any loss or liability incurred by the
Trustee through its negligence or bad faith. To secure the payment obligations of the Company in this Section 7.7, the Trustee shall have a lien prior to the Securities of any Series on all money or property held or collected by the Trustee
except such money or property held in trust to pay the principal of, interest and premium, if any, on particular Securities of that Series. 

When the Trustee incurs expenses or renders services after an Event of Default specified in Section 6.1(4) or (5) occurs, the
expenses and the compensation for the services are intended to constitute expenses of administration under any Bankruptcy Law. 
 For
purposes of this Section 7.7, the term “Trustee” shall include any trustee appointed pursuant to this Article 7. 
  

	7.8.	REPLACEMENT OF TRUSTEE. 

 The Trustee may resign with respect to the Securities of one or more
Series by so notifying the Company in writing at least 90 days in advance of such resignation. 
 The Holders of a majority in principal
amount of the outstanding Securities of any Series may remove the Trustee with respect to that Series by notifying the removed Trustee in writing and may appoint a successor Trustee with respect to that Series with the consent of the Company, which
consent shall not be unreasonably withheld. The Company may remove the Trustee with respect to that Series at its election if: 
 (1) the
Trustee fails to comply with, or ceases to be eligible under, Section 7.10; 
 (2) the Trustee is adjudged a bankrupt or an insolvent,
or an order for relief is entered with respect to the Trustee, under any Bankruptcy Law; 
 (3) a Custodian or other public officer takes
charge of the Trustee or its property; or 
 (4) the Trustee otherwise becomes incapable of acting. 

(5) If the Trustee resigns or is removed, or if a vacancy exists in the office of Trustee, with respect to any Series of Securities for any
reason, the Company shall promptly appoint, by Board Resolution, a successor Trustee. 
 If a successor Trustee with respect to the
Securities of one or more Series does not take office within 60 days after the retiring Trustee resigns or is removed, the retiring Trustee, the Company or the Holders of at least 10% in principal amount of the outstanding Securities of the
applicable Series may petition any court of competent jurisdiction for the appointment of a successor Trustee. 

  
 23 

 If the Trustee with respect to the Securities of one or more Series fails to comply with
Section 7.10, any Securityholder of the applicable Series may petition any court of competent jurisdiction for the removal of the Trustee and the appointment of a successor Trustee. 

A successor Trustee shall deliver a written acceptance of its appointment to the retiring Trustee and to the Company. Immediately following
such delivery, (i) the retiring Trustee with respect to one or more Series shall, subject to its rights under Section 7.7, transfer all property held by it as Trustee with respect to such Series to the successor Trustee, (ii) the
resignation or removal of the retiring Trustee shall become effective and (iii) the successor Trustee with respect to such Series shall have all the rights, powers and duties of the Trustee under this Indenture. A successor Trustee with respect
to the Securities of one or more Series shall mail notice of its succession to each Securityholder of such Series. 
  

	7.9.	SUCCESSOR TRUSTEE BY CONSOLIDATION, MERGER OR CONVERSION. 

 If the Trustee, or any Agent,
consolidates with, merges or converts into, or transfers all or substantially all of its corporate trust assets to, another corporation, subject to Section 7.10, the successor corporation without any further act shall be the successor Trustee
or Agent, as the case may be. 
  

	7.10.	ELIGIBILITY; DISQUALIFICATION. 

 This Indenture shall always have a Trustee who satisfies the
requirements of TIA Sections 310(a)(1), (2) and (5) in every respect. The Trustee (or in the case of a Trustee that is a Person included in a bank holding company system, the related bank holding company) shall have a combined capital and
surplus of at least $100,000,000 as set forth in its most recent published annual report of condition. The Trustee shall comply with TIA Section 310(b), including the provision in Section 310(b)(1). In addition, if the Trustee is a Person
included in a bank holding company system, the Trustee, independently of such bank holding company, shall meet the capital requirements of TIA Section 310(a)(2). If at any time the Trustee shall cease to be eligible in accordance with the
provisions of this Section 7.10, it shall resign immediately in the manner and with the effect specified in this Article 7. 
  

	7.11.	PREFERENTIAL COLLECTION OF CLAIMS AGAINST COMPANY. 

 The Trustee shall comply with TIA
Section 311(a), excluding any creditor relationship listed in TIA Section 311(b). A Trustee who has resigned or been removed shall be subject to TIA Section 311(a) to the extent indicated therein. 

 

	7.12.	PAYING AGENTS. 

 The Company shall cause each Paying Agent other than the Trustee to execute and
deliver to it and the Trustee an instrument in which such agent shall agree with the Trustee, subject to the provisions of this Section 7.12: 

(1) that it will hold all sums held by it as agent for the payment of the principal of, or interest or premium, if any, on, the Securities
(whether such sums have been paid to it by the Company or by any obligor on the Securities) in trust for the benefit of Holders of the Securities or the Trustee; 

(2) that it will at any time during the continuance of any Event of Default, upon written request from the Trustee, deliver to the Trustee all
sums so held in trust by it together with a full accounting thereof; and 
 (3) that it will give the Trustee written notice within three
Business Days after any failure of the Company (or by any obligor on the Securities) in the payment of any installment of the principal of, or interest or premium, if any, on, the Securities when the same shall be due and payable. 

  
 24 

 ARTICLE 8 

AMENDMENTS, SUPPLEMENTS AND WAIVERS 
  

	8.1.	WITHOUT CONSENT OF HOLDERS. 

 The Company, when authorized by a Board Resolution, and the
Trustee may amend or supplement this Indenture or the Securities of one or more Series without notice to or consent of any Securityholder: 

(1) to comply with Section 5.1; 

(2) to provide for certificated Securities in addition to uncertificated Securities; 

(3) to comply with any requirements of the SEC under the TIA; 

(4) to cure any ambiguity, defect or inconsistency, or to make any other change herein or in the Securities that does not materially and
adversely affect the rights of any Securityholder; 
 (5) to provide for the issuance of, and establish the form and terms and conditions
of, Securities of any Series as permitted by this Indenture; or 
 (6) to evidence and provide for the acceptance of appointment hereunder
by a successor Trustee with respect to the Securities of one or more Series, and to add to or change any of the provisions of this Indenture as shall be necessary to provide for or facilitate the administration of the trusts hereunder by more than
one Trustee. 
 The Trustee is hereby authorized to join with the Company in the execution of any supplemental indenture authorized or
permitted by the terms of this Indenture, and to make any further appropriate agreements and stipulations which may be therein contained, but the Trustee shall not be obligated to enter into any such supplemental indenture which adversely affects
its own rights, duties or immunities under this Indenture. 
  

	8.2.	WITH CONSENT OF HOLDERS. 

 (a) The Company, when authorized by a Board Resolution, and the
Trustee may amend or supplement this Indenture or the Securities of one or more Series with the written consent of the Holders of not less than a majority in aggregate principal amount of the outstanding Securities of such Series affected by such
amendment or supplement without notice to any Securityholder. The Holders of not less than a majority in aggregate principal amount of the outstanding Securities of each such Series affected by such amendment or supplement may waive compliance by
the Company in a particular instance with any provision of this Indenture or the Securities of such Series without notice to any Securityholder. Subject to Section 8.4, without the consent of each Securityholder affected, however, an amendment,
supplement or waiver may not: 
 (1) reduce the amount of Securities whose Holders must consent to an amendment, supplement or waiver to
this Indenture or the Securities; 
 (2) reduce the rate of, or change the time for payment of, interest on any Security; 

(3) reduce the principal, or change the Stated Maturity, of any Security, or reduce the amount of, or postpone the date fixed for, the payment
of any sinking fund or analogous obligation; 
 (4) make any Security payable in money other than that stated in the Security; 

(5) change the amount or time of any payment required by the Securities, or reduce the premium payable upon any redemption of the Securities,
or change the time before which no such redemption may be made; 
 (6) waive a Default or Event of Default in the payment of the principal
of, or interest or premium, if any, on, any Security (except a rescission of acceleration of the Securities of any Series by the Holders of at least a majority in principal amount of the outstanding Securities of such Series and a waiver of the
payment default that resulted from such acceleration); 

  
 25 

 (7) waive a redemption payment with respect to any Security, or change any of the provisions with
respect to the redemption of any Securities; 
 (8) make any changes in Section 6.6 or this Section 8.2, except to increase any
percentage of Securities the Holders of which must consent to any matter; or 
 (9) take any other action otherwise prohibited by this
Indenture to be taken without the consent of each Holder affected thereby. 
 (b) Upon the request of the Company, accompanied by a Board
Resolution authorizing the execution of any such supplemental indenture, and upon the receipt by the Trustee of evidence reasonably satisfactory to the Trustee of the consent of the Securityholders as aforesaid and of the documents described in
Section 8.6, the Trustee shall join with the Company in the execution of such supplemental indenture, unless such supplemental indenture affects the Trustee’s own rights, duties or immunities under this Indenture, in which case the Trustee
may in its discretion, but shall not be obligated to, enter into such supplemental indenture. 
 (c) It shall not be necessary for the
consent of the Holders under this section to approve the particular form of any proposed amendment, supplement or waiver, but it shall be sufficient if such consent approves the substance thereof. 

After an amendment or supplement under this Section becomes effective, the Company shall mail to Securityholders a notice briefly describing
the amendment or supplement. Any failure of the Company to mail any such notice, or any defect therein, shall not, however, in any way impair or affect the validity of any supplemental indenture. 

 

	8.3.	COMPLIANCE WITH TRUST INDENTURE ACT. 

 Every amendment to, or supplement of, this Indenture or
the Securities shall comply with the TIA as then in effect. 
  

	8.4.	REVOCATION AND EFFECT OF CONSENTS. 

 Until an amendment, supplement, waiver or other action
becomes effective, a consent to it by a Holder of a Security is a continuing consent conclusive and binding upon such Holder and every subsequent Holder of the same Security or portion thereof, and of any Security issued upon the transfer thereof or
in exchange therefor or in place thereof, even if notation of the consent is not made on any such Security. Any such Holder or subsequent Holder, however, may revoke the consent as to his Security or portion of a Security, if the Trustee receives
the notice of revocation before the date the amendment, supplement, waiver or other action becomes effective. 
 The Company may, but shall
not be obligated to, fix a record date for the purpose of determining the Holders entitled to consent to any amendment, supplement or waiver, which record date shall be at least 30 days prior to the first solicitation of such consent. If a record
date is fixed, then, notwithstanding the preceding paragraph, those Persons who were Holders at such record date (or their duly designated proxies), and only such Persons, shall be entitled to consent to such amendment, supplement or waiver, or to
revoke any consent previously given, whether or not such Persons continue to be Holders after such record date. 
 After an amendment,
supplement, waiver or other action becomes effective, it shall bind every Securityholder, unless it makes a change described in any of clauses (1) through (9) of Section 8.2. In that case, the amendment, supplement, waiver or other
action shall bind each Holder of a Security who has consented to it and every subsequent Holder of a Security or portion of a Security that evidences the same debt as the consenting Holder’s Security; PROVIDED, that any such waiver shall not
impair or affect the right of any Holder to receive payment of the principal of, and interest and premium, if any, on, a Security, on or after the respective due dates expressed in such Security, or to bring suit for the enforcement of any such
payment on or after such respective dates without the consent of such Holder. 

  
 26 

	8.5.	NOTATION ON OR EXCHANGE OF SECURITIES. 

 If an amendment, supplement or waiver changes the terms
of a Security of any Series, the Trustee may request the Holder of such Security to deliver it to the Trustee. In such case, the Trustee shall place an appropriate notation on such Security about the changed terms and return it to the Holder.
Alternatively, the Company, in exchange for such Security, may issue, and the Trustee shall authenticate, a new security that reflects the changed terms. Failure to make the appropriate notation or issue a new Security shall not affect the validity
and effect of such amendment, supplement or waiver. 
  

	8.6.	TRUSTEE TO SIGN AMENDMENTS, ETC. 

 The Trustee shall sign any amendment, supplement or waiver
authorized pursuant to this Article 8 if the amendment, supplement or waiver does not adversely affect the rights, duties, liabilities or immunities of the Trustee. If it does, the Trustee may, but need not, sign it. In signing or refusing to sign
such amendment, supplement or waiver the Trustee shall be entitled to receive and, subject to Section 7.1, shall be fully protected in relying upon an Officers’ Certificate and an Opinion of Counsel stating that such amendment, supplement
or waiver is authorized or permitted by this Indenture. The Company may not sign an amendment or supplement until the Board of Directors of the Company approves it. 

ARTICLE 9 
 DISCHARGE OF
INDENTURE; DEFEASANCE 
  

	9.1.	DISCHARGE OF INDENTURE. 

 The Company may terminate its obligations under the Securities of any
Series and this Indenture with respect to such Series, except the obligations referred to in the last paragraph of this Section 9.1, if there shall have been canceled by the Trustee, or delivered to the Trustee for cancellation, all Securities
of such Series theretofore authenticated and delivered (other than any Securities of such Series that are asserted to have been destroyed, lost or stolen and that shall have been replaced as provided in Section 2.8) and the Company has paid all
sums payable by it hereunder or deposited all required sums with the Trustee. 
 After such delivery the Trustee upon request shall
acknowledge in a writing prepared by or on behalf of the Company the discharge of the Company’s obligations under the Securities of such Series and this Indenture, except for those surviving obligations specified below. 

Notwithstanding the satisfaction and discharge of this Indenture, the obligations of the Company in Sections 7.7, 9.5 and 9.6 shall survive.

  

	9.2.	LEGAL DEFEASANCE. 

 The Company may at its option, by Board Resolution, be discharged from its
obligations with respect to the Securities of any Series on the date upon which the conditions set forth in Section 9.4 below are satisfied (hereinafter, “Legal Defeasance”). For this purpose, such Legal Defeasance means that the
Company shall be deemed to have paid and discharged the entire indebtedness represented by the Securities of such Series and to have satisfied all its other obligations under such Securities and this Indenture insofar as such Securities are
concerned (and the Trustee, at the expense of the Company, shall, subject to Section 9.6, execute proper instruments acknowledging the same, as are delivered to it by the Company), except for the following, which shall survive until otherwise
terminated or discharged hereunder: (A) the rights of Holders of outstanding Securities of such Series to receive solely from the trust funds described in Section 9.4 and as more fully set forth in such section, payments in respect of the
principal of, and interest and premium, if any, on, the Securities of such Series when such payments are due, (B) the Company’s obligations with respect to the Securities of such Series under Sections 2.4, 2.5, 2.6, 2.7, 2.8 and 2.9,
(C) the rights, powers, trusts, duties and immunities of the Trustee hereunder (including claims of, or payments to, the Trustee under or pursuant to Section 7.7) and (D) this Article 9. Subject to compliance

  
 27 

 
with this Article 9, the Company may exercise its option under this Section 9.2 with respect to the Securities of any Series notwithstanding the prior exercise of its option under
Section 9.3 below with respect to the Securities of such Series. 
  

	9.3.	COVENANT DEFEASANCE. 

 At the option of the Company, pursuant to a Board Resolution, the Company
shall be released from its obligations with respect to the outstanding Securities of any Series under Sections 4.2 through 4.5, inclusive, and Section 5.1, with respect to the outstanding Securities of such Series, on and after the date the
conditions set forth in Section 9.4 are satisfied (hereinafter, “Covenant Defeasance”). For this purpose, such Covenant Defeasance means that the Company may omit to comply with and shall have no liability in respect of any term,
condition or limitation set forth in any such specified section or portion thereof, whether directly or indirectly by reason of any reference elsewhere herein to any such specified Section or portion thereof or by reason of any reference in any such
specified section or portion thereof to any other provision herein or in any other document, but the remainder of this Indenture and the Securities of any Series shall be unaffected thereby. 

 

	9.4.	CONDITIONS TO LEGAL DEFEASANCE OR COVENANT DEFEASANCE. 

 The following shall be the conditions
to application of Section 9.2 or Section 9.3 to the outstanding Securities of a Series: 
 (1) the Company shall irrevocably have
deposited or caused to be deposited with the Trustee (or another trustee satisfying the requirements of Section 7.10 who shall agree to comply with the provisions of this Article 9 applicable to it) as funds in trust for the purpose of making
the following payments, specifically pledged as security for, and dedicated solely to, the benefit of the Holders of the Securities, (A) money in an amount, or (B) U.S. Government Obligations or Foreign Government Obligations which through
the scheduled payment of principal and interest in respect thereof in accordance with their terms will provide, not later than the due date of any payment, money in an amount, or (C) a combination thereof, sufficient, in the opinion of a
nationally recognized firm of independent public accountants expressed in a written certification thereof delivered to the Trustee, to pay and discharge, and which shall be applied by the Trustee (or other qualifying trustee) to pay and discharge,
the principal of, and accrued interest and premium, if any, on, the outstanding Securities of such Series at the Stated Maturity of such principal, interest or premium, if any, or on dates for payment and redemption of such principal, interest and
premium, if any, selected in accordance with the terms of this Indenture and of the Securities of such Series; 
 (2) no Event of Default or
Default with respect to the Securities of such Series shall have occurred and be continuing on the date of such deposit, or shall have occurred and be continuing at any time during the period ending on the 91st day after the date of such deposit or,
if longer, ending on the day following the expiration of the longest preference period under any Bankruptcy Law applicable to the Company in respect of such deposit as specified in the Opinion of Counsel identified in paragraph (8) below (it
being understood that this condition shall not be deemed satisfied until the expiration of such period); 
 (3) such Legal Defeasance or
Covenant Defeasance shall not cause the Trustee to have a conflicting interest for purposes of the TIA with respect to any securities of the Company; 

(4) such Legal Defeasance or Covenant Defeasance shall not result in a breach or violation of, or constitute default under, any other
agreement or instrument to which the Company is a party or by which it is bound; 
 (5) the Company shall have delivered to the Trustee an
Opinion of Counsel stating that, as a result of such Legal Defeasance or Covenant Defeasance, neither the trust nor the Trustee will be required to register as an investment company under the Investment Company Act of 1940, as amended; 

(6) in the case of an election under Section 9.2, the Company shall have delivered to the Trustee an Opinion of Counsel stating that
(i) the Company has received from, or there has been published 

  
 28 

 
by, the Internal Revenue Service a ruling to the effect that or (ii) there has been a change in any applicable Federal income tax law with the effect that, and such opinion shall confirm
that, the Holders of the outstanding Securities of such Series or Persons in their positions will not recognize income, gain or loss for Federal income tax purposes solely as a result of such Legal Defeasance and will be subject to Federal income
tax on the same amounts, in the same manner, including as a result of prepayment, and at the same times as would have been the case if such Legal Defeasance had not occurred; 

(7) in the case of an election under Section 9.3, the Company shall have delivered to the Trustee an Opinion of Counsel to the effect
that the Holders of the outstanding Securities of such Series will not recognize income, gain or loss for Federal income tax purposes as a result of such Covenant Defeasance, and will be subject to Federal income tax on the same amounts, in the same
manner and at the same times as would have been the case if such Covenant Defeasance had not occurred; 
 (8) the Company shall have
delivered to the Trustee an Officers’ Certificate and an Opinion of Counsel, each stating that all conditions precedent provided for in this Article 9 relating to either the Legal Defeasance under Section 9.2 or the Covenant Defeasance
under Section 9.3 (as the case may be) have been complied with; 
 (9) the Company shall have delivered to the Trustee an
Officers’ Certificate stating that the deposit under clause (1) was not made by the Company with the intent of defeating, hindering, delaying or defrauding any creditors of the Company or others; and 

(10) the Company shall have paid, or duly provided for payment under terms mutually satisfactory to the Company and the Trustee, all amounts
then due to the Trustee pursuant to Section 7.7. 
  

	9.5.	DEPOSITED MONEY AND U.S. AND FOREIGN GOVERNMENT OBLIGATIONS TO BE HELD IN TRUST; OTHER MISCELLANEOUS PROVISIONS. 

All money, U.S. Government Obligations and Foreign Government Obligations (including the proceeds thereof) deposited with the Trustee pursuant
to Section 9.4 in respect of the outstanding Securities shall be held in trust and applied by the Trustee, in accordance with the provisions of such Securities and this Indenture, to the payment, either directly or through any Paying Agent as
the Trustee may determine, to the Holders of such Securities, of all sums due and to become due thereon in respect of principal, accrued interest and premium, if any, but such money need not be segregated from other funds except to the extent
required by law. 
 The Company shall pay and indemnify the Trustee against any tax, fee or other charge imposed on or assessed against the
U.S. Government Obligations and Foreign Government Obligations deposited pursuant to Section 9.4 or the principal, interest and premium, if any, received in respect thereof other than any such tax, fee or other charge which by law is for the
account of the Holders of the outstanding Securities. 
 Anything in this Article 9 to the contrary notwithstanding, but subject to payment
of any of its outstanding fees and expenses, the Trustee shall deliver or pay to the Company from time to time upon Company Request any money, U.S. Government Obligations or Foreign Government Obligations held by the Trustee as provided in
Section 9.4 which, in the opinion of a nationally-recognized firm of independent public accountants expressed in a written certification thereof delivered to the Trustee, are in excess of the amount thereof which would then be required to be
deposited to effect an equivalent Legal Defeasance or Covenant Defeasance. 
  

	9.6.	REINSTATEMENT. 

 If the Trustee or Paying Agent is unable to apply any money, U.S. Government
Obligations or Foreign Government Obligations in accordance with Section 9.1, 9.2, 9.3 or 9.4 by reason of any legal proceeding or by reason of any order or judgment of any court or governmental authority enjoining, restraining or otherwise
prohibiting such application, the Company’s obligations under this Indenture and the Securities shall be revived and reinstated as though no deposit had occurred pursuant to this Article 9 until such time as the Trustee or Paying Agent is
permitted to apply all such money, U.S. Government 

  
 29 

 
Obligations or Foreign Government Obligations, as the case may be, in accordance with Section 9.1, 9.2, 9.3 or 9.4; PROVIDED, HOWEVER, that if the Company has made any payment of principal
of, or accrued interest or premium, if any, on, any Securities because of the reinstatement of its obligations, the Company shall be subrogated to the rights of the Holders of such Securities to receive such payment from the money, U.S. Government
Obligations or Foreign Government Obligations held by the Trustee or Paying Agent. 
  

	9.7.	MONEYS HELD BY PAYING AGENT. 

 In connection with the satisfaction and discharge of this
Indenture, all moneys then held by any Paying Agent under the provisions of this Indenture shall, upon demand of the Company, be paid to the Trustee, or, if sufficient moneys have been deposited pursuant to Section 9.1, to the Company, and
thereupon such Paying Agent shall be released from all further liability with respect to such moneys. 
  

	9.8.	MONEYS HELD BY TRUSTEE. 

 Any moneys deposited with the Trustee or any Paying Agent or then held
by the Company in trust for the payment of the principal of, or interest or premium, if any, on, any Security that are not applied but remain unclaimed by the Holder of such Security for two years after the date upon which the principal of, or
interest or premium, if any, on, such Security shall have respectively become due and payable shall be repaid to the Company upon Company Request, or if such moneys are then held by the Company in trust, such moneys shall be released from such
trust; and the Holder of such Security entitled to receive such payment shall thereafter, as an unsecured general creditor, look only to the Company for the payment thereof, and all liability of the Trustee or such Paying Agent with respect to such
trust money shall thereupon cease; PROVIDED, HOWEVER, that the Trustee or any such Paying Agent, before being required to make any such repayment, may, at the expense of the Company, either mail to each Securityholder affected, at the address shown
in the register of the Securities maintained by the Registrar, or cause to be published once a week for two successive weeks, in a newspaper published in the English language, customarily published each Business Day and of general circulation in the
City of New York, New York, a notice that such money remains unclaimed and that, after a date specified therein, which shall not be less than 30 days from the date of such mailing or publication, any unclaimed balance of such moneys then remaining
will be repaid to the Company. After payment to the Company or the release of any money held in trust by the Company, Securityholders entitled to the money must look only to the Company for payment as general creditors, unless applicable abandoned
property law designates another Person. 
 ARTICLE 10 

MISCELLANEOUS 
  

	10.1.	TRUST INDENTURE ACT CONTROLS. 

 If any provision of this Indenture limits, qualifies or
conflicts with another provision which is required to be included in this Indenture by the TIA, the required provision shall control. If any provision of this Indenture modifies or excludes any provision of the TIA which may be so modified or
excluded, the latter provision shall be deemed to apply to this Indenture as so modified or to be excluded, as the case may be. 
  

	10.2.	NOTICES. 

 Any notice or communication shall be given in writing and delivered in Person, sent
by facsimile (and receipt confirmed by telephone or electronic transmission report), delivered by commercial courier service or mailed by first-class mail, postage prepaid, addressed as follows: 

If to the Company: 
 Cempra,
Inc. 
 6340 Quadrangle Drive, Suite 100 

Chapel Hill, NC 27517 
 Fax:
(919) [                    ] 

Attention: Chief Financial Officer 

  
 30 

 Copy to: 

Wyrick Robbins Yates & Ponton LLP 

4101 Lake Boone Trail, Suite 300 

Raleigh, NC 27607 
 Fax:
(919) 781-4865 
 Attention: Alexander M. Donaldson, Esq. 

If to the Trustee: 
  

					
	 	  	  
	  	 
		  	
                  
                       
	  	
		  	  
	  	
		  	  
	  	

 The Company or the Trustee by written notice to the other may designate additional or different addresses for
subsequent notices or communications. Any notice or communication to the Company or the Trustee shall be deemed to have been given or made as of the date so delivered if personally delivered; when receipt is confirmed by telephone or electronic
transmission report, if sent by facsimile; and three Business Days after mailing if sent by registered or certified mail, postage prepaid (except that a notice of change of address shall not be deemed to have been given until actually received by
the addressee). 
 Any notice or communication mailed to a Securityholder shall be mailed to such Securityholder by first-class mail,
postage prepaid, at such Securityholder’s address shown on the register kept by the Registrar. 
 Failure to mail, or any defect in, a
notice or communication to a Securityholder shall not affect its sufficiency with respect to other Securityholders. If a notice or communication to a Securityholder is mailed in the manner provided above, it shall be deemed duly given, three
Business Days after such mailing, whether or not the addressee receives it. 
 In case by reason of the suspension of regular mail service,
or by reason of any other cause, it shall be impossible to mail any notice as required by this Indenture, then such method of notification as shall be made with the approval of the Trustee shall constitute a sufficient mailing of such notice. 

In the case of Global Securities, notices or communications to be given to Securityholders shall be given to the Depository, in accordance
with its applicable policies as in effect from time to time. 
 In addition to the manner provided for in the foregoing provisions, notices
or communications to Securityholders shall be given by the Company by release made to Reuters Economic Services and Bloomberg Business News. 
  

	10.3.	COMMUNICATIONS BY HOLDERS WITH OTHER HOLDERS. 

 Securityholders of any Series may communicate
pursuant to TIA Section 312(b) with other Securityholders of that Series or any other Series with respect to their rights under this Indenture or the Securities of that Series or any other Series. The Company, the Trustee, the Registrar and any
other Person shall have the protection of TIA Section 312(c). 
  

	10.4.	CERTIFICATE AND OPINION AS TO CONDITIONS PRECEDENT. 

 Upon any request or application by the
Company to the Trustee to take any action under this Indenture, the Company shall furnish to the Trustee: 
 (1) an Officers’
Certificate (which shall include the statements set forth in Section 10.5 below) stating that, in the opinion of the signers, all conditions precedent, if any, provided for in this Indenture relating to the proposed action have been complied
with; and 
 (2) an Opinion of Counsel (which shall include the statements set forth in Section 10.5 below) stating that, in the
opinion of such counsel, all such conditions precedent have been complied with. 

  
 31 

	10.5.	STATEMENT REQUIRED IN CERTIFICATE AND OPINION. 

 Each certificate and opinion with respect to
compliance with a condition or covenant provided for in this Indenture (other than pursuant to Section 4.4) shall include: 
 (1) a
statement that the Person making such certificate or opinion has read such covenant or condition; 
 (2) a brief statement as to the nature
and scope of the examination or investigation upon which the statements or opinions contained in such certificate or opinion are based; 

(3) a statement that, in the opinion of such Person, it or he has made such examination or investigation as is necessary to enable it or him
to express an informed opinion as to whether or not such covenant or condition has been complied with; and 
 (4) a statement as to whether
or not, in the opinion of such Person, such covenant or condition has been complied with. 
  

	10.6.	RULES BY TRUSTEE AND AGENTS. 

 The Trustee may make reasonable rules for action by or at
meetings of Securityholders. The Registrar and Paying Agent may make reasonable rules for their functions. 
  

	10.7.	BUSINESS DAYS; LEGAL HOLIDAYS; PLACE OF PAYMENT. 

 A “Business Day” is a day that is
not a Legal Holiday. A “Legal Holiday” is a Saturday, a Sunday, a federally-recognized holiday or a day on which banking institutions are not authorized or required by law, regulation or executive order to be open in the State of New York.

 If a payment date is a Legal Holiday at a Place of Payment, payment may be made at that place on the next succeeding day that is not a
Legal Holiday, and no interest shall accrue for the intervening period. “Place of Payment” means the place or places where the principal of, and interest and premium, if any, on, the Securities of a Series are payable as specified as
contemplated by Section 2.2. If the regular record date is a Legal Holiday, the record date shall not be affected. 
  

	10.8.	GOVERNING LAW. 

 THIS INDENTURE AND THE SECURITIES SHALL BE GOVERNED BY AND CONSTRUED IN
ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK, AS APPLIED TO CONTRACTS MADE AND PERFORMED WITHIN THE STATE OF NEW YORK WITHOUT REGARD TO PRINCIPLES OF CONFLICTS OF LAW. 

 

	10.9.	NO ADVERSE INTERPRETATION OF OTHER AGREEMENTS. 

 This Indenture may not be used to interpret
another indenture, loan, security or debt agreement of the Company or any Subsidiary thereof. No such indenture, loan, security or debt agreement may be used to interpret this Indenture. 

  
 32 

	10.10.	NO RECOURSE AGAINST OTHERS. 

 A director, officer, employee, stockholder or incorporator, as
such, of the Company shall not have any liability for any obligations of the Company under the Securities or the Indenture. Each Securityholder by accepting a Security waives and releases all such liability. Such waiver and release are part of the
consideration for the issuance of the Securities. 
  

	10.11.	SUCCESSORS. 

 All covenants and agreements of the Company in this Indenture and the Securities
shall bind the Company’s successors and assigns, whether so expressed or not. All agreements of the Trustee, any additional trustee and any Paying Agents in this Indenture shall bind their respective successors and assigns. 

 

	10.12.	MULTIPLE COUNTERPARTS. 

 The parties may sign multiple counterparts of this Indenture. Each
signed counterpart shall be deemed an original, but all of them together represent one and the same agreement. 
  

	10.13.	TABLE OF CONTENTS, HEADINGS, ETC. 

 The table of contents, cross-reference sheet and headings of
the Articles and Sections of this Indenture have been inserted for convenience of reference only, are not to be considered a part hereof, and shall in no way modify or restrict any of the terms or provisions hereof. 

 

	10.14.	SEVERABILITY. 

 Each provision of this Indenture shall be considered separable, and if for any
reason any provision which is not essential to the effectuation of the basic purpose of this Indenture or the Securities shall be invalid, illegal or unenforceable, the validity, legality and enforceability of the remaining provisions shall not in
any way be affected or impaired thereby, and a Holder shall have no claim therefor against any party hereto. 
  

	10.15.	SECURITIES IN A FOREIGN CURRENCY OR IN EUROS. 

 Unless otherwise specified in a Board
Resolution, a supplemental indenture hereto or an Officers’ Certificate delivered pursuant to Section 2.2 with respect to a particular Series of Securities, whenever for purposes of this Indenture any action may be taken by the Holders of
a specified percentage in aggregate principal amount of Securities of all Series or all Series affected by a particular action at the time outstanding and, at such time, there are outstanding Securities of any Series which are denominated in a coin
or currency other than Dollars (including Euros), then the principal amount of Securities of such Series which shall be deemed to be outstanding for the purpose of taking such action shall be that amount of Dollars that could be obtained for such
amount at the Market Exchange Rate at such time. For purposes of this Section 10.15, “Market Exchange Rate” shall mean the noon Dollar buying rate in New York City for cable transfers of that currency as published by the Federal
Reserve Bank of New York; PROVIDED, HOWEVER, in the case of Euros, Market Exchange Rate shall mean the rate of exchange determined by the Commission of the European Union (or any successor thereto) as published in the Official Journal of the
European Union (such publication or any successor publication, the “Journal”). If such Market Exchange Rate is not available for any reason with respect to such currency, the Trustee shall use, in its sole discretion and without liability
on its part, such quotation of the Federal Reserve Bank of New York or, in the case of Euros, the rate of exchange as published in the Journal, as of the most recent available date, or quotations or, in the case of Euros, rates of exchange from one
or more major banks in New York City or in the country of issue of the currency in question or, in the case of Euros, in Luxembourg or such other quotations or, in the case of Euros, rates of exchange as the Trustee, upon consultation with the
Company, shall deem appropriate. The provisions of this paragraph shall apply in determining the equivalent principal amount in respect of Securities of a Series denominated in currency other than Dollars in connection with any action taken by
Holders of Securities pursuant to the terms of this Indenture. 
 All decisions and determinations of the Trustee regarding the Market
Exchange Rate or any alternative determination provided for in the preceding paragraph shall be in the Trustee’s sole discretion, and shall, in the absence of manifest error, be conclusive to the extent permitted by law for all purposes and
irrevocably binding upon the Company and all Holders. 

  
 33 

	10.16.	JUDGMENT CURRENCY. 

 The Company agrees, to the fullest extent that it may effectively do so
under applicable law, that (a) if for the purpose of obtaining judgment in any court it is necessary to convert the sum due in respect of the principal of, or interest or premium, if any, or other amount on, the Securities of any Series (the
“Required Currency”) into a currency in which a judgment will be rendered (the “Judgment Currency”), the rate of exchange used shall be the rate at which, in accordance with normal banking procedures, the Trustee could purchase
in The City of New York the Required Currency with the Judgment Currency on the day on which final unappealable judgment is entered, unless such day is not a Business Day, in which instance, the rate of exchange used shall be the rate at which, in
accordance with normal banking procedures, the Trustee could purchase in The City of New York the Required Currency with the Judgment Currency on the Business Day preceding the day on which final unappealable judgment is entered and (b) its
obligations under this Indenture to make payments in the Required Currency (i) shall not be discharged or satisfied by any tender or any recovery pursuant to any judgment (whether or not entered in accordance with subsection (a)) in any
currency other than the Required Currency, except to the extent that such tender or recovery shall result in the actual receipt, by the payee, of the full amount of the Required Currency expressed to be payable in respect of such payments,
(ii) shall be enforceable as an alternative or additional cause of action for the purpose of recovering in the Required Currency the amount, if any, by which such actual receipt shall fall short of the full amount of the Required Currency so
expressed to be payable and (iii) shall not be affected by judgment being obtained for any other sum due under this Indenture. 
 IN
WITNESS WHEREOF, the parties hereto have caused this Indenture to be duly executed, and their respective corporate seals to be hereunto affixed and attested, all as of the day and year first above written. 

 

			
	CEMPRA, INC.
		
	By:	 	  

	Name:	 	  

	Title:	 	  

	
	[Name of Trustee]
		
	By:	 	  

	Name:	 	  

	Title:	 	  

		
	By:	 	  

	Name:	 	  

	Title:	 	  

  
 34

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