Document:

Ex-4.32

 

Exhibit 4.32

Protherics PLC

The Heath Business and

Technical Park

Runcorn

Cheshire WA7 4QX

Tel:   01928 518000

Fax:  01928 518002

24 May 2007

Mr Stuart Wallis

Briarwood

Nightingales Lane

Chalfont St Giles

Bucks 
HP8 4SR

Dear Stuart

APPOINTMENT AS NON-EXECUTIVE CHAIRMAN OF PROTHERICS PLC

This letter confirms the main terms of your appointment to the above office and replaces
your letter of appointment dated 1 September 1998 with effect from 1 April 2007.

Under this agreement, you will continue to serve the Company as Non-executive Chairman,
based at the Company’s corporate office at 3 Creed Court, 5 Ludgate Hill, London EC4M
7AA. Please note that your appointment is subject to the Company’s articles of
association as amended from time to time. If there is a conflict between the terms of
this letter and the articles of association then the articles shall prevail.

DUTIES

	1.	 	As you are aware, the Board as a whole is collectively responsible for promoting
the success of the Company by directing and supervising the Company’s affairs and
that its role is to:

	 	a)	 	provide entrepreneurial leadership to the Company within a
framework of prudent and effective controls which enable risk to be assessed
and managed;
	 
	 	b)	 	set the Company’s strategic aims, ensure that the necessary
financial and human resources are in place for the Company to meet its
objectives, and review management performance; and
	 
	 	c)	 	set the Company’s values and standards and ensure that its
obligations to its shareholders and others are understood and met.

	 	 	 	 	 	 	 
	NORTH AMERICA

	 	EUROPE
	 	AUSTRALASIA
	 	W.W.W.PROTHERICS.COM
	PROTHERICS INC

	 	PROTHERICS PLC
	 	PROTHERICS AUSTRALASIA P/L
	 	REGISTERED OFFICE:
	5214 MARYLAND WAY

	 	3 CREED COURT
	 	RSD TURRETFIELD RC
	 	PROTHERICS PLC 
	SUITE #405

	 	5 LUDGATE HILL
	 	HOLLAND RD, ROSEDALE
	 	THE HEATH BUSINESS & TECHNICAL PARK 
	BRENTWOOD TN

	 	LONDON EC4M 7AA UK
	 	SA 5350 AUSTRALIA
	 	RUNCORN, CHESHIRE WA7 4QX
	37027 USA
Tel: +1 615 327 1027

	 	Tel: +44 (0)20 7246 9950
	 	Tel: +61 (0)8 8524 9700
	 	 REGISTERED IN ENGLAND AND WALES 
NO. 2459087

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	2.	 	In your role as Non-executive Chairman you are required to:

	 	a)	 	provide leadership of the Board, ensuring its effectiveness on all
aspects of its role and set its agenda;
	 
	 	b)	 	ensure that, so far as reasonably possible, the corporate governace of the
Company conforms to prevailing guidelines;
	 
	 	c)	 	ensure that the directors receive accurate, timely and clear information;
	 
	 	d)	 	ensure that there is effective communication with shareholders;
	 
	 	e)	 	ensure constructive relations between executive and non-executive directors;
	 
	 	f)	 	facilitate the effective contribution of directors to ensure that
they fulfil their duties;
	 
	 	g)	 	ensure that the directors continually update their skills and
knowledge in order to fulfil their role both on the board and where relevant on
board committees;
	 
	 	h)	 	constructively challenge and contribute to the development of strategy;
	 
	 	i)	 	scrutinise the performance of management in meeting agreed goals and
objectives and monitor the reporting of performance;
	 
	 	j)	 	satisfy yourself that financial information is accurate and that
financial controls and systems of risk management are robust and defensible;
	 
	 	k)	 	be responsible, along with the remuneration committee, for
determining appropriate levels of remuneration of executive directors and have a
prime role in appointing, and where necessary removing senior management, and in
succession planning

	3.	 	You are also required to:

	 	a)	 	exercise relevant powers under the Company’s memorandum and articles
of association;
	 
	 	b)	 	perform your duties faithfully, efficiently and diligently and use all reasonable endeavours to promote the interests and reputation of the
Company;
	 
	 	c)	 	comply with your fiduciary duties;
	 
	 	d)	 	report the wrongdoing (including acts of misconduct, dishonesty,
breaches of contract, fiduciary duty, company rules or the rules of the relevant
regulatory bodies) whether committed, contemplated or discussed by any other
director or member of staff of the Company and any group company of which you
were aware to the Board immediately, irrespective of whether this may involve
some degree of self incrimination;
	 
	 	e)	 	serve as chairman of the Board’s nomination committee and as a
member of its remuneration committee and attend, wherever possible, all meetings
of the

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	 	 	 	Board’s committees as appropriate (committee meetings may occasionally be
scheduled separately from Board Meetings);
	 
	 	f)	 	attend and chair all general meetings of the Company;
	 
	 	g)	 	attend, wherever possible, all meetings of the Board, which meet
on an agreed schedule and will normally be held at the Company’s corporate
office at 3 Creed Court, 5 Ludgate Hill, London EC4M 7AA, with occasional
meetings held at other Company locations;
	 
	 	h)	 	consider all relevant papers in advance of each meeting in order to
ensure that you can play a full part in the work of the Board and its committees;
	 
	 	i)	 	bring independent judgement to bear on issues of strategy, policy,
resources, performance and standards of conduct;
	 
	 	I)	 	make yourself available (on reasonable notice) to provide ad hoc
advice to individual directors of the Company;
	 
	 	m)	 	provide guidance and direction in planning, developing and enhancing the
future strategic direction of the Company;
	 
	 	n)	 	share responsibility with the other directors for the effective
control of the Company and with the other non-executive directors for the
supervision of the executive directors; and
	 
	 	o)	 	 comply with all legal and regulatory requirements and any code of
practice or compliance manual issued by the Company relating to transactions in
securities and inside information and dealing in force from time to time,
including any rules and regulations of or under the UK Listing authority
(including the Model Code for transactions in securities by directors and
certain others in listed companies, the Listing Rules, the Disclosure Rules and
the Prospectus Rules), the Financial Services and Markets Act 2000, the Criminal
Justice Act 1993, the Financial Services Authority and relevant regulatory
authorities relevant to the Company.

	4.	 	Overall, the Company anticipates that you will need to spend an average of one day per
week fulfilling your duties. This will include the board meetings, general meetings, annual
strategy meeting, and where appropriate will also include meetings with shareholders and
site visits. In addition, you will be expected to spend an appropriate period of time
preparing for each meeting. By accepting the terms of this letter of appointment you confirm
that you are able to commit sufficient time to the role to meet the Company’s expectations.

	5.	 	The Company seeks to adhere to the principles in the Financial Reporting Council Combined
Code on Corporate Governance, the Turnbull Report on Internal Control, the Smith Guidance on
Audit Committees and best practice for non-executive directors as outlined in the Higgs
Report. You Will be expected to carry out your duties in accordance with the principles laid
out in these documents, copies of which are available from the Company Secretary.

	6.	 	The performance of the Board and its committees and of individual directors is evaluated
annually.

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	7.	 	You shall, in pursuance of your duties hereunder, be entitled to request such information from
the Company, its subsidiary undertakings (as defined in section 258 of the Companies Act 1985 as
amended from time to time) or its or their employees, consultants or professional advisers as may
be reasonably necessary to enable you to perform your role effectively. The Company shall use its
reasonable endeavours to provide such information promptly.

CONFIDENTIALITY

During the course of your duties you will have access to confidential information belonging to
the Company and its subsidiary undertakings (including but not limited to, details of
suppliers, customers, margins, know-how, marketing and other relevant business information).
Unauthorised disclosure of this information could seriously damage the Company. You therefore
undertake not to use or disclose such information save in pursuance of your duties or in
accordance with any statutory obligation or court or similar order.

Your attention is drawn to the rules relating to the disclosure of price sensitive
information. You must not make any statement or do anything which may be a breach of these
rules without prior clearance from the Board.

OUTSIDE INTERESTS

The agreement of the Board should be sought before you accept any new outside interests which
might affect the time you are able to devote to this appointment.

In accordance with the principles set out in the Combined Code you must inform the Board of
any interests which you have, or acquire, which might reasonably be thought to jeopardise your
independence from the Company. You must also advise the Board of changes to your other
significant work commitments as they arise.

During your appointment you must not take up any office or employment with, or have any
interest in, any firm or company which is or may be in direct or indirect competition with the
Company.

The Board have determined you to be independent, according to the provisions of the Combined
Code.

INSURANCE

During your appointment you will be covered by the Company’s directors’ and officers’
liability insurance on the terms currently in place for the rest of the Board. The current
indemnity limit is £20 million. A copy of the policy document is available from the Company
Secretary. The Company does not guarantee to maintain this insurance cover after the
termination of your appointment, but you will continue to be covered by the policy or any
replacement on the same basis as the rest of the Board.

You will not be eligible for membership of the Company’s permanent health or private medical
insurance schemes.

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PENSION

You will be responsible for your own pension arrangements and no contributions will be payable by
the company.

COMPANY CAR

The Company shall provide you with a fully expensed car of a standard as agreed from time to time
with the Remuneration Committee.

APPOINTMENT

Your appointment remains terminable by twelve months’ notice from either the Company or yourself.
The continuation of your appointment depends upon satisfactory performance and re-election at
forthcoming Annual General Meetings.

Notwithstanding the aforementioned notice provisions, the Company may terminate your appointment
with immediate effect if you have:

	a)	 	committed any serious breach or (after warning in writing) any repeated or continued
material breach of your obligations to the Company (which include an obligation not to breach
your fiduciary duties);
	 
	b)	 	been guilty of any act of dishonesty or serious misconduct or any conduct which (in the
reasonable opinion of the Board) tends to bring you or the Company into disrepute; or
	 
	c)	 	been declared bankrupt or have made an arrangement or composition with or for the benefit
of your creditors,

or for any other reason set out in the Company’s articles of association.

All appointments and reappointments to the Board are subject to the Company’s articles of
association. If you are not re-elected to your position as a director of the Company by the
shareholders at any time and for any reason then this appointment shall terminate automatically
and with immediate effect.

On termination of the appointment you shall only be entitled to such fees as may have accrued to
the date of termination together with reimbursement in the normal way of any expenses properly
incurred prior to that date.

REMUNERATION

The fee payable for your services under the terms of this contract is £55,000 per annum (subject
to income tax and statutory deductions) and is payable monthly in arrears. It may be subject to
upward review at the discretion of the Company. If you undertake any special duties beyond those
specified in this letter you will not receive any additional payment unless agreed with the Board
in advance.

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EXPENSES

The Company will reimburse you for any expenses that you may incur properly and reasonably in
performing your duties and which are properly documented. Such expenses would include reasonable
legal fees if circumstances should arise in which it was necessary for you to seek separate legal
advice about the performance of your duties. In such a situation, you are required to discuss the
issue either with me or with one of your non-executive colleagues in advance.

INDEPENDENT PROFESSIONAL ADVICE.

In some circumstances you may think that you need professional advice in the furtherance of your
duties as a director. It may also be appropriate for you to seek advice from independent
advisers at the Company’s expense. A copy of the Board’s agreed procedure under which directors
may obtain such independent advice is available from the Company Secretary. The Company will
reimburse the full cost of any expenditure incurred in accordance with the policy.

DATA PROTECTION

By signing this agreement you consent to the Company holding and processing information about
you which you may provide or which it may acquire during the course of this agreement, providing
such use is in accordance with the Data Protection Act 1998. In particular, you consent to the
Company holding and processing:

	a)	 	personal data relating to you, for administrative and management purposes; and
	 
	b)	 	“sensitive personal data” relating to you (as defined in the Data Protection Act 1998)
including, for example:

	 	i)	 	your health records and any medical reports given to or obtained by the
Company, for monitoring sick leave and taking decisions as to your fitness to work;
	 
	 	ii)	 	your racial or ethnic origin (in order to monitor compliance with the Race
Relations Act 1976);
	 
	 	iii)	 	any information relating to criminal proceedings in which you have been
involved for compliance with the Company’s legal or regulatory requirements, for
insurance purposes, and in relation to its obligations to third parties.

You also consent to the Company making such information available to:

	a)	 	its group companies, officers and (if necessary) customers outside the European Economic
Area in order to further its business interests; and
	 
	b)	 	its group companies, its officers, those who provide products or services to the Company,
regulatory authorities, governmental or quasi governmental organisations and potential
purchasers of the Company or its business.

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THIRD PARTY RIGHTS

The Contracts (Rights of Third Parties) act 1999 shall not apply to this agreement. No
person other than the parties to this agreement and any group company shall have any rights
under it and it will not be enforceable by any person other than those parties.

Please sign and return the enclosed copy of this letter to confirm your agreement to the above
terms.

Yours sincerely

For and on behalf of the Board
 

Andrew Heath

Chief Executive Officer

I, Stuart Wallis, agree to the above terms of appointment as Non-executive Chairman
of Protherics PLC.

	 	 	 	 	 
	Signature:

	 	/s/ Stuart Wallis
 

	 	  
	 
	 	 	 	 
	Date:

	 	24/5/2007	 	 
	 
	 	 	 	 
	In the presence of:	 	 
	 
	 	 	 	 
	Witness signature:

	 	/s/ Julie Vickers
 

	 	 
	 
	 	 	 	 
	Witness name:

	 	Julie Vickers	 	 
	 
	 	 	 	 
	Witness address:

	 	57, WHITE PARK CLOSE	 	 
	 
	 	 	 	 
	 

	 	MIDDLE WICH	 	 
	 
	 	 	 	 
	 

	 	CHESHIRE CWIO 9GB	 	 
	 
	 	 	 	 
	Witness occupation:

	 	CHARTERED SECRETARY	 	 

Page 7 of 7Ex-4.33

 

Exhibit 4.33

CONSULTANCY AGREEMENT

This Consultancy Agreement (the “Agreement”) is effective from 1 April 2007 and
is made between PROTHERICS PLC (“Protherics” or the “Company”) whose
registered office is the Heath Business and Technical Park, Runcorn,
Cheshire WA7 4QX (registered in England and Wales under number 02459087) and
“STUART MICHAEL WALLIS of Briarwood, Nightingales Lane, Chalfont St. Giles,
Buckinghamshire HP8 4SR trading as “Stuart Wallis Associates” (the “Consultant”)
and replaces the consultancy agreement dated 1 September 1998 made between
Therapeutic Antibodies (UK) Limited and “Stuart M Wallis” trading as “Stuart Wallis
Associates” (the “Consultant”).

	1.	 	THE ADVICE
	 
	 	 	The Consultant has agreed with the Company on the terms set out below
that he will provide to the Company in relation to the management and
expansion of the business of the Company and its subsidiaries (the “Group”),
the consultancy advice as outlined in Schedule 1 to the Agreement (the
“Advice”).
	 
	2.	 	DURATION OF AGREEMENT
	 
	 	 	Subject to the terms herein, the Agreement will continue until 12
months’ notice of termination is given by either party.
	 
	3.	 	FEE
	 
	3.1	 	The Company shall pay to the Consultant a fee of £25,000 per annum exclusive
of VAT payable on a pro rata basis monthly in arrears, subject to prior receipt
by the Company of an appropriate invoice under Clause 3.2 below.
	 
	3.2	 	The Consultant shall submit an invoice (together with a VAT invoice if
applicable) each month giving details of the amount of the fee due and any
expenses to be reclaimed under Clause 3.3 below.
	 
	3.3	 	The Company will pay to the Consultant the amount of any reasonable expenses
wholly and necessarily incurred by him in the provision of the Advice but
subject to the Company’s prior written approval of such expenses and such
expenses being evidenced in such a manner as the Company may specify from time
to time.
	 
	3.4	 	The Company shall be entitled to deduct from any sums due to the Consultant
any amounts that the Consultant may owe the Company at any time.
	 
	4.	 	OBLIGATIONS OF THE CONSULTANT
	 
	 	 	During the term of the Agreement the Consultant shall:-
	 
	4.1	 	provide the Advice to the Company to the best of his skill and ability as
required by the Company and in the provision of that advice will use his best
endeavours always to promote and protect the interests of the Group. The
Consultant shall devote such hours to his obligations under this Agreement as
are reasonably necessary for the proper provision of the Advice, which shall be
on average around 1.5 days per month. The actual days upon which the Consultant
shall provide his services shall be agreed between the consultant and the
Company.

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	4.2	 	attend the Company’s corporate office at 3 Creed Court, 5 Ludgate Hill,
London EC4M 7AA or such other place as he is reasonably required to attend for the
proper provision of the Advice;
	 
	4.3	 	(it being acknowledged by the Company that the detailed provision of the Advice is a
matter for the Consultant) observe the Company’s general guidance and instruction with
regard to the provision of the Advice;
	 
	4.4	 	maintain full and proper confidentiality in relation to all information belonging to
the Company or any of its clients of a confidential nature whether oral, written or
electronically recorded concerning the business and affairs of the Company and the Group
and any other information specifically identified by the Company as confidential or
known to the Consultant as being held by the Company under a duty of confidentiality to
a third party, in either case coming to his attention in the course of or for the
purposes of his providing the Advice;
	 
	4.5	 	comply properly with the requirements of all relevant legislation and agreements
relating to payment of value added tax, income and other taxes and charges,
levied in respect of the Company’s use of his services and the fees payable to him under
the Agreement;
	 
	5.	 	NON-EXCLUSIVITY OF SERVICE
	 
	 	 	Nothing in the Agreement will prevent the Consultant from being directly or
indirectly concerned with or supplying similar consultancy services to any third party
during or after the term of this Agreement provided in all cases that such interests
or services shall not entail or be likely to lead to a breach of the Consultant’s
confidentiality obligations to the Company or otherwise interfere in any way with the
full and efficient performance of the Consultant’s obligations in respect of the
Advice. The Consultant shall not supply similar consultancy services to any third
party if the proposed appointment could give rise to a direct or indirect conflict of
interest with the interests of the Group.
	 
	6.	 	OTHER INTERESTS
	 
	 	 	The consultant will not accept any non-executive appointments which are either with
competitors of the Group or which will affect the Consultant’s ability to provide the
Advice under the Agreement save with the prior written consent of the Company.
	 
	7.	 	RELATIONSHIP
	 
	7.1	 	The consultant is an independent contractor of the Company. Nothing in this
Agreement shall render the Consultant an agent or partner of the Company and the
Consultant shall not hold himself out as such. The Consultant will indemnify the Company
against any liability, assessment or claim:

	 	7.1.1	 	for taxation or for statutory deductions where such liability,
assessment or claim arises or is made in connection with the provision of his
services and to the extent that any payment to the Consultant shall give rise to
any liability on the Company, the amount payable by the Consultant under this
indemnity will be increased so that the amount after such tax is sufficient to
effect such indemnity provided that this undertaking does not confer any right on
the Company to recover from the Consultant secondary Class 1

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	 	 	 	national insurance contributions to the extent that recovery of the same is
prohibited by law; and
	 
	 	7.1.2	 	for unfair dismissal or other employment claims that the Consultant may
bring against the Company in respect of the provision of his services under this
Agreement.

	8.	 	ASSIGNMENT AND SUBSTITUTION
	 
	 	 	No rights or obligations under this Agreement may be assigned by the Consultant
save with the prior written consent of the Company. The Consultant may not use any
other person to provide the Advice to the Company in his place or subcontract it, save
with the prior written consent of the Company.
	 
	9.	 	TITLE TO WORK
	 
	 	 	The Consultant acknowledges that he shall not acquire rights or title to any intellectual
property or any Advice provided by him for the purposes of the
Company under this Agreement. The rights and title in all Advice provided by the Consultant
to the Company shall be and remain with the Company as shall those rights in any documents
provided to the Consultant for the purposes of his providing the Advice and in any notes,
copies or extracts derived from those documents which the Consultant might make in the
drawing up or delivery of the Advice. The Consultant shall at the request and cost of the
Company do such acts as may be required by the Company in order to assign the rights
referred to in this clause to, and secure them for, the Company. This obligation shall
survive the termination of this Agreement.
	 
	10.	 	PROVISIONS ON TERMINATION GENERALLY
	 
	10.1	 	On termination of the agreement for whatever reason the Consultant shall:-

	 	10.1.1	 	deliver to the Company forthwith all property of its or any of its clients which may
then be in his possession or control, including without limitation any records, plans,
programs, designs, specifications, samples and documentation in any form and shall, in
the case of any data held on his own computer, irretrievably erase all such data, code
and programs;
	 
	 	10.1.2	 	thereafter observe the duty of confidentiality as set out in 4.5 of the
Agreement notwithstanding its termination.

	10.2	 	The Company shall have the right to terminate the Agreement immediately without payment to
the Consultant (other than for any figures by way of fee or expenses accrued due up to the
date of that termination) if the Consultant becomes bankrupt, is convicted of an indictable
offence, commits any act of dishonesty in his provision of the Advice, commits a material
breach of any of the terms of this Agreement or, after notice in writing, wilfully neglects
to provide or fails to remedy any default in providing the Advice. Any delay by the Company in
exercising such right to terminate shall not be a waiver thereof.
	 
	11.	 	GOVERNING LAW
	 
	11.1	 	The Agreement (and any dispute, controversy, proceedings or claim of whatever nature
arising out of or in any way relating to this Agreement or its formation) shall be governed by
and construed in accordance with the laws of England.

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	11.2	 	Each of the parties to this Agreement irrevocably agrees that the courts of
England shall have exclusive jurisdiction to hear and decide any suit, action or
proceedings, and/or to settle any disputes, which arise out of or in connection
with this Agreement and, for these purposes, each party irrevocably submits to the
jurisdiction of the courts of England.
	 
	12.	 	NOTICES

	12.1	 	Any notice or other document to be served under the Agreement must, in the case of the
Company, be delivered by hand or sent by first class post or facsimile process to the Company
at its registered office marked for the attention of the Company Secretary and, in the case of
the Consultant, must be delivered or sent by first class post to the Consultant’s residential
address as advised from time to time to the Company in writing.
	 
	12.2	 	Any such notice or other document shall be deemed to have been served:

	 	12.2.1	 	if delivered by hand, on the date of delivery;
	 
	 	12.2.2	 	if posted by first class post, on the second day (being any day other than a
Saturday, Sunday or bank holiday) (“Working Day”) after the date it was posted; or
	 
	 	12.2.3	 	if sent by facsimile process and received by 12.00 noon, on the date of receipt,
otherwise it shall be deemed to have been received on the Working Day following the
date of receipt.

	12.3	 	As evidence of such service it shall be sufficient to prove that delivery was made by hand or
that the envelope containing such notice or other document was properly addressed and posted
as a pre-paid first class letter or that the facsimile message was properly addressed and
despatched as the case may be.
	 
	13.	 	ENTIRE AGREEMENT AND PREVIOUS CONTRACTS
	 
	13.1	 	Each party on behalf of itself (and in the case of the Company acting also as agent for
the members of the Group) acknowledges and agrees with the other party that:

	 	13.1.1	 	this Agreement constitutes the entire and only agreement between the Consultant and
any member of the Group relating to his consultancy with the Company;
	 
	 	13.1.2	 	neither it nor any member of the Group has been induced to enter into this Agreement
in reliance upon any warranty, representation, statement, assurance, undertaking or
commitment of any nature whatsoever other than as expressly set out in this Agreement
and, to the extent that any of them has been induced, it (in the case of the Company,
acting on behalf of all members of the Group) unconditionally and irrevocably waives
any claims, rights or remedies which it or any of them might otherwise have in relation
thereto;
	 
	 	13.1.3	 	the provisions of this clause 13.1 shall not exclude any liability which any of the
parties or, where appropriate, the members of the Group would otherwise have in
relation to fraud.

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	13.2	 	Any previous arrangement between the Company or any member of the Group and the
Consultant relating to his consultancy with the Company shall be deemed to have been
terminated by mutual consent from the date of the Agreement.

Signed for and on behalf of

PROTHERICS PLC

	 	 	 	 	 
	/s/ John Brown
 

	 	 
	 	Date: 23/5/07
	John Brown (Director)
	 	 	 	 
	 
	 	 	 	 
	

	 	 	 	Date: 23/5/07
	Andrew Heath (Director)
	 	 	 	 
	 
	 	 	 	 
	and
	 	 	 	 
	 
	 	 	 	 
	Signed
by the CONSULTANT
	 	 	 	 
	 
	 	 	 	 
	/s/ Stuart Michael Wallis
 

Stuart Michael Wallis

	 	 
	 	Date: 24/5/2007

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SCHEDULE 1

The Advice

The advice the Consultant will provide to the company will be in relation to the following:-

	1.	 	Overseeing the implementation of such methods devised by the Consultant for the strategic
development and growth of the Company (and the Group) as are adopted by the Company;

	2.	 	Acting as an interface with City institutions and their representatives on behalf of the
Company (and the Group).

-6-

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