Document:

EX-4.1

 EXHIBIT 4.1 
  

 
  

ERYTECH PHARMA S.A. 
 AND 

THE BANK OF NEW YORK MELLON 

                        
                                         
                   As Depositary 
 AND 

OWNERS AND HOLDERS OF AMERICAN DEPOSITARY SHARES 

Amended and Restated Deposit Agreement 

Dated as of             , 2017 

 
  

 

 TABLE OF CONTENTS 
  

							
	 ARTICLE 1.
	 	 DEFINITIONS
	  	 	1	 
	 SECTION 1.1.
	 	 American Depositary Shares.
	  	 	2	 
	 SECTION 1.2.
	 	 Commission.
	  	 	2	 
	 SECTION 1.3.
	 	 Company.
	  	 	2	 
	 SECTION 1.4.
	 	 Custodian.
	  	 	2	 
	 SECTION 1.5.
	 	 Delisting Event.
	  	 	3	 
	 SECTION 1.6.
	 	 Deliver; Surrender.
	  	 	3	 
	 SECTION 1.7.
	 	 Deposit Agreement.
	  	 	3	 
	 SECTION 1.8.
	 	 Depositary; Depositary’s Office.
	  	 	4	 
	 SECTION 1.9.
	 	 Deposited Securities.
	  	 	4	 
	 SECTION 1.10.
	 	 Disseminate.
	  	 	4	 
	 SECTION 1.11.
	 	 Dollars.
	  	 	4	 
	 SECTION 1.12.
	 	 DTC.
	  	 	4	 
	 SECTION 1.13.
	 	 Foreign Registrar.
	  	 	4	 
	 SECTION 1.14.
	 	 Holder.
	  	 	4	 
	 SECTION 1.15.
	 	 Insolvency Event.
	  	 	5	 
	 SECTION 1.16.
	 	 Owner.
	  	 	5	 
	 SECTION 1.17.
	 	 Receipts.
	  	 	5	 
	 SECTION 1.18.
	 	 Registrar.
	  	 	5	 
	 SECTION 1.19.
	 	 Replacement.
	  	 	5	 
	 SECTION 1.20.
	 	 Restricted Securities.
	  	 	5	 
	 SECTION 1.21.
	 	 Securities Act of 1933.
	  	 	6	 
	 SECTION 1.22.
	 	 Shares.
	  	 	6	 
	 SECTION 1.23.
	 	 SWIFT.
	  	 	6	 
	 SECTION 1.24.
	 	 Termination Option Event.
	  	 	6	 
			
	 ARTICLE 2.
	 	 FORM OF RECEIPTS, DEPOSIT OF SHARES, DELIVERY, TRANSFER AND SURRENDER OF AMERICAN DEPOSITARY
SHARES
	  	 	6	 
	 SECTION 2.1.
	 	 Form of Receipts; Registration and Transferability of American Depositary Shares.
	  	 	6	 
	 SECTION 2.2.
	 	 Deposit of Shares.
	  	 	7	 
	 SECTION 2.3.
	 	 Delivery of American Depositary Shares.
	  	 	8	 
	 SECTION 2.4.
	 	 Registration of Transfer of American Depositary Shares; Combination and Split-up of Receipts;
Interchange of Certificated and Uncertificated American Depositary Shares.
	  	 	9	 
	 SECTION 2.5.
	 	 Surrender of American Depositary Shares and Withdrawal of Deposited Securities.
	  	 	10	 

  
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	 SECTION 2.6.
	 	 Limitations on Delivery, Transfer and Surrender of American Depositary Shares.
	  	 	11	 
	 SECTION 2.7.
	 	 Lost Receipts, etc.
	  	 	11	 
	 SECTION 2.8.
	 	 Cancellation and Destruction of Surrendered Receipts.
	  	 	12	 
	 SECTION 2.9.
	 	 Pre-Release of American Depositary Shares.
	  	 	12	 
	 SECTION 2.10.
	 	 DTC Direct Registration System and Profile Modification System.
	  	 	12	 
			
	 ARTICLE 3.
	 	 CERTAIN OBLIGATIONS OF OWNERS AND HOLDERS OF AMERICAN DEPOSITARY SHARES
	  	 	13	 
	 SECTION 3.1.
	 	 Filing Proofs, Certificates and Other Information.
	  	 	13	 
	 SECTION 3.2.
	 	 Liability of Owner for Taxes.
	  	 	14	 
	 SECTION 3.3.
	 	 Warranties on Deposit of Shares.
	  	 	15	 
	 SECTION 3.4.
	 	 Disclosure of Interests.
	  	 	15	 
			
	 ARTICLE 4.
	 	 THE DEPOSITED SECURITIES
	  	 	16	 
	 SECTION 4.1.
	 	 Cash Distributions.
	  	 	16	 
	 SECTION 4.2.
	 	 Distributions Other Than Cash, Shares or Rights.
	  	 	16	 
	 SECTION 4.3.
	 	 Distributions in Shares.
	  	 	17	 
	 SECTION 4.4.
	 	 Rights.
	  	 	18	 
	 SECTION 4.5.
	 	 Conversion of Foreign Currency.
	  	 	19	 
	 SECTION 4.6.
	 	 Fixing of Record Date.
	  	 	20	 
	 SECTION 4.7.
	 	 Voting of Deposited Shares.
	  	 	21	 
	 SECTION 4.8.
	 	 Tender and Exchange Offers; Redemption, Replacement or Cancellation of Deposited
Securities.
	  	 	22	 
	 SECTION 4.9.
	 	 Reports.
	  	 	24	 
	 SECTION 4.10.
	 	 Lists of Owners.
	  	 	24	 
	 SECTION 4.11.
	 	 Withholding.
	  	 	24	 
			
	 ARTICLE 5.
	 	 THE DEPOSITARY, THE CUSTODIANS AND THE COMPANY
	  	 	25	 
	 SECTION 5.1.
	 	 Maintenance of Office and Transfer Books by the Depositary.
	  	 	25	 
	 SECTION 5.2.
	 	 Prevention or Delay in Performance by the Depositary or the Company.
	  	 	25	 
	 SECTION 5.3.
	 	 Obligations of the Depositary and the Company.
	  	 	26	 
	 SECTION 5.4.
	 	 Resignation and Removal of the Depositary.
	  	 	27	 
	 SECTION 5.5.
	 	 The Custodians.
	  	 	28	 
	 SECTION 5.6.
	 	 Notices and Reports.
	  	 	28	 
	 SECTION 5.7.
	 	 Distribution of Additional Shares, Rights, etc.
	  	 	29	 

  
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	 SECTION 5.8.
	 	 Indemnification.
	  	 	29	 
	 SECTION 5.9.
	 	 Charges of Depositary.
	  	 	30	 
	 SECTION 5.10.
	 	 Retention of Depositary Documents.
	  	 	31	 
	 SECTION 5.11.
	 	 Exclusivity.
	  	 	31	 
			
	 ARTICLE 6.
	 	 AMENDMENT AND TERMINATION
	  	 	32	 
	 SECTION 6.1.
	 	 Amendment.
	  	 	32	 
	 SECTION 6.2.
	 	 Termination.
	  	 	32	 
			
	 ARTICLE 7.
	 	 MISCELLANEOUS
	  	 	33	 
	 SECTION 7.1.
	 	 Counterparts; Signatures.
	  	 	33	 
	 SECTION 7.2.
	 	 No Third Party Beneficiaries.
	  	 	34	 
	 SECTION 7.3.
	 	 Severability.
	  	 	34	 
	 SECTION 7.4.
	 	 Owners and Holders as Parties; Binding Effect.
	  	 	34	 
	 SECTION 7.5.
	 	 Notices.
	  	 	34	 
	 SECTION 7.6.
	 	 Appointment of Agent for Service of Process; Submission to Jurisdiction; Jury Trial
Waiver.
	  	 	35	 
	 SECTION 7.7.
	 	 Waiver of Immunities.
	  	 	36	 
	 SECTION 7.8.
	 	 Governing Law.
	  	 	36	 

  
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 AMENDED AND RESTATED DEPOSIT AGREEMENT 

AMENDED AND RESTATED DEPOSIT AGREEMENT dated as of             ,
2017 among ERYTECH PHARMA S.A., a company incorporated under the laws of France (herein called the Company), THE BANK OF NEW YORK MELLON, a New York banking corporation (herein called the Depositary), and all Owners and Holders (each as
hereinafter defined) from time to time of American Depositary Shares issued hereunder. 
 W I T N E S S E T H: 

WHEREAS, the Company and the Depositary entered into a deposit agreement dated as of January 9, 2015 (the “Prior Deposit
Agreement”) for the purposes stated in that agreement; 
 WHEREAS, the Company and the Depositary now wish to amend the Prior Deposit
Agreement and the form of Receipt to reflect that the American Depositary Shares are listed on the Nasdaq Global Market and the Company has become a reporting company under the Securities Exchange Act of 1934 and to provide additional disclosure
language regarding the conversion of foreign currency; 
 WHEREAS, the Company desires to provide, as set forth in this Amended and
Restated Deposit Agreement (herein called this Deposit Agreement), for the deposit of Shares (as hereinafter defined) of the Company from time to time with the Depositary or with the Custodian (as hereinafter defined) under this Deposit Agreement,
for the creation of American Depositary Shares representing the Shares so deposited and for the execution and delivery of American Depositary Receipts evidencing the American Depositary Shares; and 

WHEREAS, the American Depositary Receipts are to be substantially in the form of Exhibit A annexed to this Deposit Agreement, with
appropriate insertions, modifications and omissions, as set forth in this Deposit Agreement; 
 NOW, THEREFORE, in consideration of the
premises, it is agreed by and between the parties hereto that the Prior Deposit Agreement is hereby amended and restated as follows: 

ARTICLE 1. DEFINITIONS 
 The
following definitions shall for all purposes, unless otherwise clearly indicated, apply to the respective terms used in this Deposit Agreement: 

  
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 SECTION 1.1. American Depositary Shares. 

The term “American Depositary Shares” shall mean the securities created under this Deposit Agreement representing rights with
respect to the Deposited Securities. American Depositary Shares may be certificated securities evidenced by Receipts or uncertificated securities. The form of Receipt annexed as Exhibit A to this Deposit Agreement shall be the prospectus required
under the Securities Act of 1933 for sales of both certificated and uncertificated American Depositary Shares. Except for those provisions of this Deposit Agreement that refer specifically to Receipts, all the provisions of this Deposit Agreement
shall apply to both certificated and uncertificated American Depositary Shares. 
 Each American Depositary Share shall represent the
number of Shares specified in Exhibit A to this Deposit Agreement, except that, if there is a distribution upon Deposited Securities covered by Section 4.3, a change in Deposited Securities covered by Section 4.8 with respect to
which additional American Depositary Shares are not delivered or a sale of Deposited Securities under Section 3.2 or 4.8, each American Depositary Share shall thereafter represent the amount of Shares or other Deposited Securities that are then
on deposit per American Depositary Share after giving effect to that distribution, change or sale. 
 SECTION 1.2. Commission. 

The term “Commission” shall mean the Securities and Exchange Commission of the United States or any successor governmental
agency in the United States. 
 SECTION 1.3. Company. 

The term “Company” shall mean ERYTECH Pharma S.A., a company incorporated under the laws of France, and its successors. 

SECTION 1.4. Custodian. 

The term “Custodian” shall mean Société Générale, as custodian for the Depositary in Paris for
the purposes of this Deposit Agreement, and any other firm or corporation the Depositary appoints under Section 5.5 as a substitute or additional custodian under this Deposit Agreement, and shall also mean all of them collectively. 

SECTION 1.5. Delisting Event. 

A “Delisting Event” occurs if the American Depositary Shares are delisted from a securities exchange on which the American
Depositary Shares were listed and the Company has not listed or applied to list the American Depositary Shares on any other securities exchange. 

  
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 SECTION 1.6. Deliver; Surrender. 

(a) The term “deliver”, or its noun form, when used with respect to Shares or other Deposited Securities, shall mean
(i) book-entry transfer of those Shares or other Deposited Securities to an account maintained by an institution authorized under applicable law to effect transfers of such securities designated by the person entitled to that delivery or
(ii) physical transfer of certificates evidencing those Shares or other Deposited Securities registered in the name of, or duly endorsed or accompanied by proper instruments of transfer to, the person entitled to that delivery. 

(b) The term “deliver”, or its noun form, when used with respect to American Depositary Shares, shall mean
(i) registration of those American Depositary Shares in the name of DTC or its nominee and book-entry transfer of those American Depositary Shares to an account at DTC designated by the person entitled to that delivery, (ii) registration
of those American Depositary Shares not evidenced by a Receipt on the books of the Depositary in the name requested by the person entitled to that delivery and mailing to that person of a statement confirming that registration or (iii) if
requested by the person entitled to that delivery, execution and delivery at the Depositary’s Office to the person entitled to that delivery of one or more Receipts evidencing those American Depositary Shares registered in the name requested by
that person. 
 (c) The term “surrender”, when used with respect to American Depositary Shares, shall
mean (i) one or more book-entry transfers of American Depositary Shares to the DTC account of the Depositary, (ii) delivery to the Depositary at its Office of an instruction to surrender American
Depositary Shares not evidenced by a Receipt or (iii) surrender to the Depositary at its Office of one or more Receipts evidencing American Depositary Shares. 

SECTION 1.7. Deposit Agreement. 

The term “Deposit Agreement” shall mean this Amended and Restated Deposit Agreement, as it may be amended from time to time
in accordance with the provisions hereof. 
 SECTION 1.8. Depositary; Depositary’s Office. 

The term “Depositary” shall mean The Bank of New York Mellon, a New York banking corporation, and any successor as depositary
under this Deposit Agreement. The term “Office”, when used with respect to the Depositary, shall mean the office at which its depositary receipts business is administered, which, at the date of this Deposit Agreement, is located at
101 Barclay Street, New York, New York 10286. 

  
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 SECTION 1.9. Deposited Securities. 

The term “Deposited Securities” as of any time shall mean Shares at such time deposited or deemed to be deposited under this
Deposit Agreement, including without limitation, Shares that have not been successfully delivered upon surrender of American Depositary Shares, and any and all other securities, property and cash received by the Depositary or the Custodian in
respect of Deposited Securities and at that time held under this Deposit Agreement. 
 SECTION 1.10. Disseminate. 

The term “Disseminate,” when referring to a notice or other information to be sent by the Depositary to Owners, shall mean
(i) sending that information to Owners in paper form by mail or another means or (ii) with the consent of Owners, another procedure that has the effect of making the information available to Owners, which may include (A) sending the
information by electronic mail or electronic messaging or (B) sending in paper form or by electronic mail or messaging a statement that the information is available and may be accessed by the Owner on an Internet website and that it will be
sent in paper form upon request by the Owner, when that information is so available and is sent in paper form as promptly as practicable upon request. 

SECTION 1.11. Dollars. 

The term “Dollars” shall mean United States dollars. 

SECTION 1.12. DTC. 
 The
term “DTC” shall mean The Depository Trust Company or its successor. 
 SECTION 1.13. Foreign Registrar. 

The term “Foreign Registrar” shall mean the entity that carries out the duties of registrar for the Shares and any other
agent of the Company for the transfer and registration of Shares, including, without limitation, any securities depository for the Shares. 

SECTION 1.14. Holder. 

The term “Holder” shall mean any person holding a Receipt or a security entitlement or other interest in American Depositary
Shares, whether for its own account or for the account of another person, but that is not the Owner of that Receipt or those American Depositary Shares. 

  
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 SECTION 1.15. Insolvency Event. 

An “Insolvency Event” occurs if the Company institutes proceedings to be adjudicated as bankrupt or insolvent, consents to
the institution of bankruptcy or insolvency proceedings against it, files a petition or answer or consent seeking reorganization or relief under any applicable law in respect of bankruptcy or insolvency, consents to the filing of any petition of
that kind or to the appointment of a receiver, liquidator, assignee, trustee, custodian or sequestrator (or other similar official) of it or any substantial part of its property or makes an assignment for the benefit of creditors, or if information
becomes publicly available indicating that unsecured claims against the Company are not expected to be paid. 
 SECTION 1.16. Owner.

 The term “Owner” shall mean the person in whose name American Depositary Shares are registered on the books of the
Depositary maintained for that purpose. 
 SECTION 1.17. Receipts. 

The term “Receipts” shall mean the American Depositary Receipts issued under this Deposit Agreement evidencing certificated
American Depositary Shares, as the same may be amended from time to time in accordance with the provisions of this Deposit Agreement. 

SECTION 1.18. Registrar. 

The term “Registrar” shall mean any corporation or other entity that is appointed by the Depositary to register American
Depositary Shares and transfers of American Depositary Shares as provided in this Deposit Agreement. 
 SECTION 1.19. Replacement.

 The term “Replacement” shall have the meaning assigned to it in Section 4.8. 

SECTION 1.20. Restricted Securities. 

The term “Restricted Securities” shall mean Shares that (i) are “restricted securities,” as defined in Rule
144 under the Securities Act of 1933, except for Shares that could be resold in reliance on Rule 144 without any conditions, (ii) are beneficially owned by an officer, director (or person performing similar functions) or other affiliate of the
Company, (iii) otherwise would require registration under the Securities Act of 1933 in connection with the public offer and sale thereof in the United States or (iv) are subject to other restrictions on sale or deposit under the laws of
France, a shareholder agreement or the articles of association or similar document of the Company. 

  
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 SECTION 1.21. Securities Act of 1933. 

The term “Securities Act of 1933” shall mean the United States Securities Act of 1933, as from time to time amended. 

SECTION 1.22. Shares. 

The term “Shares” shall mean ordinary shares of the Company that are validly issued and outstanding, fully paid and
nonassessable and that were not issued in violation of any pre-emptive or similar rights of the holders of outstanding securities of the Company; provided, however, that, if there shall occur any change in nominal or par value, a
split-up or consolidation or any other reclassification or, upon the occurrence of an event described in Section 4.8, an exchange or conversion in respect of the Shares of the Company, the term “Shares” shall thereafter also mean the
successor securities resulting from such change in nominal value, split-up or consolidation or such other reclassification or such exchange or conversion. 

SECTION 1.23. SWIFT. 

The term “SWIFT” shall mean the financial messaging network operated by the Society for Worldwide Interbank Financial
Telecommunication, or its successor. 
 SECTION 1.24. Termination Option Event. 

The term “Termination Option Event” shall mean an event of a kind defined as such in Section 4.1, 4.2 or 4.8. 

ARTICLE 2. FORM OF RECEIPTS, DEPOSIT OF SHARES, DELIVERY, TRANSFER AND SURRENDER OF AMERICAN DEPOSITARY SHARES 

SECTION 2.1. Form of Receipts; Registration and Transferability of American Depositary Shares. 

Definitive Receipts shall be substantially in the form set forth in Exhibit A to this Deposit Agreement, with appropriate insertions,
modifications and omissions, as permitted under this Deposit Agreement. No Receipt shall be entitled to any benefits under this Deposit Agreement or be valid or obligatory for any purpose, unless that Receipt has been (i) executed by the
Depositary by the manual signature of a duly authorized officer of the Depositary or (ii) executed by the facsimile signature of a duly authorized officer of the Depositary and countersigned by the manual signature of a duly authorized
signatory of the Depositary or the Registrar or a co-registrar. The Depositary 

  
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shall maintain books on which (x) each Receipt so executed and delivered as provided in this Deposit Agreement and each transfer of that Receipt and (y) all American Depositary Shares
delivered as provided in this Deposit Agreement and all registrations of transfer of American Depositary Shares, shall be registered. A Receipt bearing the facsimile signature of a person that was at any time a proper officer of the Depositary
shall, subject to the other provisions of this paragraph, bind the Depositary, even if that person was not a proper officer of the Depositary on the date of issuance of that Receipt. 

The Receipts and statements confirming registration of American Depositary Shares may have incorporated in or attached to them such legends
or recitals or modifications not inconsistent with the provisions of this Deposit Agreement as may be required by the Depositary or required to comply with any applicable law or regulations thereunder or with the rules and regulations of any
securities exchange upon which American Depositary Shares may be listed or to conform with any usage with respect thereto, or to indicate any special limitations or restrictions to which any particular Receipts and American Depositary Shares are
subject by reason of the date of issuance of the underlying Deposited Securities or otherwise. 
 American Depositary Shares evidenced by a
Receipt, when the Receipt is properly endorsed or accompanied by proper instruments of transfer, shall be transferable as certificated registered securities under the laws of the State of New York. American Depositary Shares not evidenced by
Receipts shall be transferable as uncertificated registered securities under the laws of the State of New York. The Depositary, notwithstanding any notice to the contrary, may treat the Owner of American Depositary Shares as the absolute owner
thereof for the purpose of determining the person entitled to distribution of dividends or other distributions or to any notice provided for in this Deposit Agreement and for all other purposes, and neither the Depositary nor the Company shall have
any obligation or be subject to any liability under this Deposit Agreement to any Holder of American Depositary Shares (but only to the Owner of those American Depositary Shares). 

SECTION 2.2. Deposit of Shares. 

Subject to the terms and conditions of this Deposit Agreement, Shares or evidence of rights to receive Shares may be deposited under this
Deposit Agreement by delivery thereof to any Custodian, accompanied by any appropriate instruments or instructions for transfer, or endorsement, in form satisfactory to the Custodian. 

As conditions of accepting Shares for deposit, the Depositary may require (i) any certification required by the Depositary or the
Custodian in accordance with the provisions of this Deposit Agreement, (ii) a written order directing the Depositary to deliver to, or upon the written order of, the person or persons stated in that order American Depositary Shares representing
those deposited Shares, (iii) evidence satisfactory to the Depositary that those Shares have been re-registered in the books of the Company or the Foreign Registrar in the name of the Depositary, a Custodian or a

  
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nominee of the Depositary or a Custodian, (iv) evidence satisfactory to the Depositary that any necessary approval has been granted by any governmental body in each applicable jurisdiction
and (v) an agreement or assignment, or other instrument satisfactory to the Depositary, that provides for the prompt transfer to the Custodian of any dividend, or right to subscribe for additional Shares or to receive other property, that any
person in whose name those Shares are or have been recorded may thereafter receive upon or in respect of those Shares, or, in lieu thereof, such agreement of indemnity or other agreement as shall be satisfactory to the Depositary. 

At the request and risk and expense of a person proposing to deposit Shares, and for the account of that person, the Depositary may receive
certificates for Shares to be deposited, together with the other instruments specified in this Section, for the purpose of forwarding those Share certificates to the Custodian for deposit under this Deposit Agreement. 

The Depositary shall instruct each Custodian that, upon each delivery to a Custodian of a certificate or certificates for Shares to be
deposited under this Deposit Agreement, together with the other documents specified in this Section, that Custodian shall, as soon as transfer and recordation can be accomplished, present that certificate or those certificates to the Company or the
Foreign Registrar, if applicable, for transfer and recordation of the Shares being deposited in the name of the Depositary or its nominee or that Custodian or its nominee. 

Deposited Securities shall be held by the Depositary or by a Custodian for the account and to the order of the Depositary or at such other
place or places as the Depositary shall determine. 
 SECTION 2.3. Delivery of American Depositary Shares. 

The Depositary shall instruct each Custodian that, upon receipt by that Custodian of any deposit pursuant to Section 2.2, together with
the other documents or evidence required under that Section, that Custodian shall notify the Depositary of that deposit and the person or persons to whom or upon whose written order American Depositary Shares are deliverable in respect thereof. Upon
receiving a notice of a deposit from a Custodian, or upon the receipt of Shares or evidence of the right to receive Shares by the Depositary, the Depositary, subject to the terms and conditions of this Deposit Agreement, shall deliver, to or upon
the order of the person or persons entitled thereto, the number of American Depositary Shares issuable in respect of that deposit, but only upon payment to the Depositary of the fees and expenses of the Depositary for the delivery of those American
Depositary Shares as provided in Section 5.9, and of all taxes and governmental charges and fees payable in connection with that deposit and the transfer of the deposited Shares. However, the Depositary shall deliver only whole numbers
of American Depositary Shares. 

  
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 SECTION 2.4. Registration of Transfer of American Depositary Shares; Combination and Split-up
of Receipts; Interchange of Certificated and Uncertificated American Depositary Shares. 
 The Depositary, subject to the terms and
conditions of this Deposit Agreement, shall register a transfer of American Depositary Shares on its transfer books upon (i) in the case of certificated American Depositary Shares, surrender of the Receipt evidencing those American Depositary
Shares, by the Owner or by a duly authorized attorney, properly endorsed or accompanied by proper instruments of transfer or (ii) in the case of uncertificated American Depositary Shares, receipt from the Owner of a proper instruction
(including, for the avoidance of doubt, instructions through DRS and Profile as provided in Section 2.10), and, in either case, duly stamped as may be required by the laws of the State of New York and of the United States of America. Upon
registration of a transfer, the Depositary shall deliver the transferred American Depositary Shares to or upon the order of the person entitled thereto. 

The Depositary, subject to the terms and conditions of this Deposit Agreement, shall upon surrender of a Receipt or Receipts for the purpose
of effecting a split-up or combination of such Receipt or Receipts, execute and deliver a new Receipt or Receipts for any authorized number of American Depositary Shares requested, evidencing the same aggregate number of American Depositary Shares
as the Receipt or Receipts surrendered. 
 The Depositary, upon surrender of certificated American Depositary Shares for the purpose of
exchanging for uncertificated American Depositary Shares, shall cancel the Receipt evidencing those certificated American Depositary Shares and send the Owner a statement confirming that the Owner is the owner of the same number of uncertificated
American Depositary Shares. The Depositary, upon receipt of a proper instruction (including, for the avoidance of doubt, instructions through DRS and Profile as provided in Section 2.10) from the Owner of uncertificated American Depositary
Shares for the purpose of exchanging for certificated American Depositary Shares, shall cancel those uncertificated American Depositary Shares and register and deliver to the Owner a Receipt evidencing the same number of certificated American
Depositary Shares. 
 The Depositary may appoint one or more co-transfer agents for the purpose of effecting registration of transfers of
American Depositary Shares and combinations and split-ups of Receipts at designated transfer offices on behalf of the Depositary, and the Depositary shall notify the Company of any such appointment. In carrying out its functions, a co-transfer agent
may require evidence of authority and compliance with applicable laws and other requirements by Owners or persons entitled to American Depositary Shares and will be entitled to protection and indemnity to the same extent as the Depositary. 

  
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 SECTION 2.5. Surrender of American Depositary Shares and Withdrawal of Deposited
Securities. 
 Upon surrender at the Depositary’s Office of American Depositary Shares for the purpose of withdrawal of the
Deposited Securities represented thereby and payment of the fee of the Depositary for the surrender of American Depositary Shares as provided in Section 5.9 and payment of all taxes and governmental charges payable in connection with that
surrender and withdrawal of the Deposited Securities, and subject to the terms and conditions of this Deposit Agreement, the Owner of those American Depositary Shares shall be entitled to delivery (to the extent delivery can then be lawfully and
practicably made), to or as instructed by that Owner, of the amount of Deposited Securities at the time represented by those American Depositary Shares, but not any money or other property as to which a record date for distribution to Owners has
passed. That delivery shall be made, as provided in this Section, without unreasonable delay. 
 As a condition of accepting a surrender of
American Depositary Shares for the purpose of withdrawal of Deposited Securities, the Depositary may require (i) that each surrendered Receipt be properly endorsed in blank or accompanied by proper instruments of transfer in blank and
(ii) that the surrendering Owner execute and deliver to the Depositary a written order directing the Depositary to cause the Deposited Securities being withdrawn to be delivered to or upon the written order of a person or persons designated in
that order. 
 Thereupon, the Depositary shall direct the Custodian to deliver, subject to Sections 2.6, 3.1 and 3.2, the other terms and
conditions of this Deposit Agreement and local market rules and practices, to the surrendering Owner or to or upon the written order of the person or persons designated in the order delivered to the Depositary as above provided, the amount of
Deposited Securities represented by the surrendered American Depositary Shares. 
 At the request, risk and expense of an Owner
surrendering American Depositary Shares for withdrawal of Deposited Securities, and for the account of that Owner, the Depositary shall direct the Custodian to forward any cash or other property comprising, and forward a certificate or certificates,
if applicable, and other proper documents of title, if any, for, the Deposited Securities represented by the surrendered American Depositary Shares to the Depositary for delivery at the Depositary’s Office or to another address specified in the
order received from the surrendering Owner. 
 The Depositary shall direct the Custodian to make delivery of Deposited Securities and may
charge the surrendering Owner a fee and the Depositary’s expenses for doing so. 

  
 -10- 

 SECTION 2.6. Limitations on Delivery, Transfer and Surrender of American Depositary
Shares. 
 As a condition precedent to the delivery, registration of transfer or surrender of any American Depositary Shares or split-up
or combination of any Receipt or withdrawal of any Deposited Securities, the Depositary, Custodian or Registrar may require payment from the depositor of Shares or the presenter of the Receipt or instruction for registration of transfer or surrender
of American Depositary Shares not evidenced by a Receipt of a sum sufficient to reimburse it for any tax or other governmental charge and any stock transfer or registration fee with respect thereto (including any such tax or charge and fee with
respect to Shares being deposited or withdrawn) and payment of any applicable fees as provided in this Deposit Agreement, may require the production of proof satisfactory to it as to the identity and genuineness of any signature and may also require
compliance with any regulations the Depositary may establish consistent with the provisions of this Deposit Agreement, including, without limitation, this Section 2.6. 

The delivery of American Depositary Shares against deposit of Shares generally or against deposit of particular Shares may be suspended, or
the registration of transfer of American Depositary Shares in particular instances may be refused, or the registration of transfer of outstanding American Depositary Shares generally may be suspended, during any period when the transfer books of the
Depositary are closed, or if any such action is deemed necessary or advisable by the Depositary or the Company at any time or from time to time because of any requirement of law or of any government or governmental body or commission, or under any
provision of this Deposit Agreement, or for any other reason. Notwithstanding anything to the contrary in this Deposit Agreement, the surrender of outstanding American Depositary Shares and withdrawal of Deposited Securities may not be suspended,
subject only to (i) temporary delays caused by closing the transfer books of the Depositary or the Company or the Foreign Registrar, if applicable, or the deposit of Shares in connection with voting at a shareholders’ meeting, or the
payment of dividends, (ii) the payment of fees, taxes and similar charges, and (iii) compliance with any U.S. or foreign laws or governmental regulations relating to the American Depositary Shares or to the withdrawal of the Deposited
Securities; in each case, the Depositary shall notify the Company as promptly as practicable of any such suspension or delay that is outside the ordinary course of business. 

The Depositary shall not knowingly accept for deposit under this Deposit Agreement any Shares that, at the time of deposit, are Restricted
Securities. 
 SECTION 2.7. Lost Receipts, etc. 

If a Receipt is mutilated, destroyed, lost or stolen, the Depositary shall deliver to the Owner the American Depositary Shares evidenced by
that Receipt in uncertificated form or, if requested by the Owner, execute and deliver a new Receipt of like tenor in exchange and substitution for such mutilated Receipt, upon surrender and 

  
 -11- 

 
cancellation of that mutilated Receipt, or in lieu of and in substitution for that destroyed, lost or stolen Receipt. However, before the Depositary will deliver American Depositary Shares
in uncertificated form or execute and deliver a new Receipt, in substitution for a destroyed, lost or stolen Receipt, the Owner must (a) file with the Depositary (i) a request for that replacement before the Depositary has notice that the
Receipt has been acquired by a bona fide purchaser and (ii) a sufficient indemnity bond and (b) satisfy any other reasonable requirements imposed by the Depositary. 

SECTION 2.8. Cancellation and Destruction of Surrendered Receipts. 

The Depositary shall cancel all Receipts surrendered to it and is authorized to destroy Receipts so cancelled. 

SECTION 2.9. Pre-Release of American Depositary Shares. 

Notwithstanding Section 2.3, and unless otherwise instructed in writing by the Company, the Depositary may deliver American Depositary
Shares prior to the receipt of Shares pursuant to Section 2.2 (a “Pre-Release”). The Depositary may, pursuant to Section 2.5, deliver Shares upon the surrender of American Depositary Shares that have been Pre-Released,
whether or not that surrender is prior to the termination of that Pre-Release or the Depositary knows that those American Depositary Shares have been Pre-Released. The Depositary may receive American Depositary Shares in lieu of Shares in
satisfaction of a Pre-Release. Each Pre-Release must be (a) preceded or accompanied by a written representation from the person to whom American Depositary Shares or Shares are to be delivered, that such person, or its customer, owns the Shares
or American Depositary Shares to be remitted, as the case may be, (b) at all times fully collateralized with cash or such other collateral as the Depositary deems appropriate, (c) terminable by the Depositary on not more than five
(5) business days’ notice, and (d) subject to all indemnities and credit regulations that the Depositary deems appropriate. The number of American Depositary Shares outstanding at any time as a result of Pre-Release will not normally
exceed thirty percent (30%) of all American Depositary Shares outstanding; provided, however, that the Depositary reserves the right to change or disregard that limit from time to time as it deems appropriate. 

The Depositary may retain for its own account any compensation received by it in connection with Pre-Release. 

SECTION 2.10. DTC Direct Registration System and Profile Modification System. 

(a) Notwithstanding the provisions of Section 2.4, the parties acknowledge that DTC’s Direct Registration System
(“DRS”) and Profile Modification System (“Profile”) apply to the American Depositary Shares upon acceptance thereof to DRS by DTC. DRS is the system administered by DTC that facilitates interchange between
registered holding of uncertificated securities and holding of security 

  
 -12- 

 
entitlements in those securities through DTC and a DTC participant. Profile is a required feature of DRS that allows a DTC participant, claiming to act on behalf of an Owner of American
Depositary Shares, to direct the Depositary to register a transfer of those American Depositary Shares to DTC or its nominee and to deliver those American Depositary Shares to the DTC account of that DTC participant without receipt by the Depositary
of prior authorization from the Owner to register that transfer. 
 (b) In connection with DRS/Profile, the parties acknowledge that the
Depositary will not determine whether the DTC participant that is claiming to be acting on behalf of an Owner in requesting a registration of transfer and delivery as described in paragraph (a) above has the actual authority to act on behalf of
that Owner (notwithstanding any requirements under the Uniform Commercial Code). For the avoidance of doubt, the provisions of Sections 5.3 and 5.8 apply to the matters arising from the use of the DRS/Profile. The parties agree that the
Depositary’s reliance on and compliance with instructions received by the Depositary through the DRS/Profile system and otherwise in accordance with this Deposit Agreement shall not constitute negligence or bad faith on the part of the
Depositary. 
 ARTICLE 3. CERTAIN OBLIGATIONS OF OWNERS AND HOLDERS OF AMERICAN DEPOSITARY SHARES 

SECTION 3.1. Filing Proofs, Certificates and Other Information. 

Any person presenting Shares for deposit or any Owner or Holder may be required from time to time to file with the Depositary or the Custodian
such proof of citizenship or residence, exchange control approval, or such information relating to the registration on the books of the Company or the Foreign Registrar, if applicable, to execute such certificates and to make such representations
and warranties, as the Depositary may deem necessary or proper. The Depositary may withhold the delivery or registration of transfer of American Depositary Shares, the distribution of any dividend or other distribution or of the proceeds thereof or
the delivery of any Deposited Securities until that proof or other information is filed or those certificates are executed or those representations and warranties are made. 

Each Holder and Owner agrees to comply with requests from the Company pursuant to applicable law and regulations, the rules and requirements
of the Euronext Paris stock exchange, the Nasdaq Global Market and of any other stock exchange on which the Shares or American Depositary Shares are, or may be, registered, traded or listed and any book-entry settlement system or the articles of
association or similar document of the Company, which are made to provide information, inter alia, as to the capacity in which such Holder or Owner owns American Depositary Shares (and Shares, as the case may be) and regarding the identity of any
other person(s) interested in such American Depositary Shares and the nature of such interest and various other matters, whether or not they are Holders or Owners at the time of such request. The Depositary agrees to use its reasonable efforts to
forward, upon the request of the 

  
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Company and at the Company’s expense (unless otherwise agreed between the Company and the Depositary), any such request from the Company to the Owners and to forward to the Company any such
responses to such requests received by the Depositary, to the extent that disclosure is permitted under applicable law. 
 Holders and
Owners of American Depositary Shares may be required from time to time, and in a timely manner, to file such proof of taxpayer status, residence and beneficial ownership (as applicable), to execute such certificates and to make such representations
and warranties, or to provide any other information or documents, as the Company, the Depositary or the Custodian may deem necessary or proper to fulfill the Company’s, the Depositary’s or the Custodian’s obligations under applicable
law. 
 SECTION 3.2. Liability of Owner for Taxes. 

If any tax or other governmental charge shall become payable by the Company, the Custodian or the Depositary with respect to or in connection
with any American Depositary Shares or any Deposited Securities represented by any American Depositary Shares or in connection with a transaction to which Section 4.8 applies, that tax or other governmental charge shall be payable by the Owner
of those American Depositary Shares to the Company or the Depositary (for further payment to the Custodian if applicable). The Depositary may refuse to register any transfer of those American Depositary Shares or any withdrawal of Deposited
Securities represented by those American Depositary Shares until that payment is made, and may withhold any dividends or other distributions or the proceeds thereof, or may sell for the account of the Owner any part or all of the Deposited
Securities represented by those American Depositary Shares and apply those dividends or other distributions or the net proceeds of any sale of that kind in payment of that tax or other governmental charge but, even after a sale of that kind,
the Owner of those American Depositary Shares shall remain liable for any deficiency. The Depositary shall distribute any net proceeds of a sale made under this Section that are not used to pay taxes or governmental charges to the Owners entitled to
them in accordance with Section 4.1. If the number of Shares represented by each American Depositary Share decreases as a result of a sale of Deposited Securities under this Section, the Depositary may call for surrender of the American
Depositary Shares to be exchanged on a mandatory basis for a lesser number of American Depositary Shares and may sell American Depositary Shares to the extent necessary to avoid distributing fractions of American Depositary Shares in that exchange
and distribute the net proceeds of that sale to the Owners entitled to them. 
 Every Holder and Owner agrees to indemnify the Depositary,
the Company, the Custodian, and any of their respective agents, directors, officers, employees and affiliates (as such term is defined in Regulation C under the Securities Act of 1933) for, and to hold each of them harmless from, any claims by any
governmental authority or any other entity or person with respect to taxes, additions to tax, penalties or interest arising out of any refund of taxes, reduced rate of withholding at source or other 

  
 -14- 

 
tax benefit obtained. The obligations of Holders and Owners of American Depositary Shares under this Section 3.2 of the Deposit Agreement shall survive any transfer of American Depositary
Shares, any surrender of American Depositary Shares and withdrawal of Deposited Securities, as well as the termination of the Deposit Agreement. 

SECTION 3.3. Warranties on Deposit of Shares. 

Every person depositing Shares under this Deposit Agreement shall be deemed thereby to represent and warrant that those Shares and each
certificate therefor, if applicable, are validly issued, fully paid and nonassessable and were not issued in violation of any preemptive or similar rights of the holders of outstanding securities of the Company and that the person making that
deposit is duly authorized so to do. Every depositing person shall also be deemed to represent that the Shares, at the time of deposit, are not Restricted Securities. All representations and warranties deemed made under this Section shall survive
the deposit of Shares and delivery of American Depositary Shares. 
 SECTION 3.4. Disclosure of Interests. 

In order to comply with applicable laws and regulations or the articles of association or similar document of the Company, the Company may
from time to time request each Owner and Holder to provide to the Depositary information relating to: (a) the capacity in which it holds American Depositary Shares, (b) the identity of any Holders or other persons or
entities then or previously interested in those American Depositary Shares and the nature of those interests and (c) any other matter where disclosure of such matter is required for that compliance. Each Owner and Holder agrees
to provide all information known to it in response to a request made pursuant to this Section. Each Holder consents to the disclosure by the Owner or any other Holder through which it holds American Depositary Shares, directly or
indirectly, of all information responsive to a request made pursuant to this Section relating to that Holder that is known to that Owner or other Holder. The Depositary agrees to use reasonable efforts, at the Company’s expense
(unless otherwise agreed between the Company and the Depositary), to comply with written instructions requesting that the Depositary forward any request authorized under this Section to the Owners and to forward to the Company any responses it
receives in response to that request. 
 Each Owner and Holder of American Depositary Shares further agrees to comply with the laws and
regulations of the United States and the Republic of France (if and to the extent applicable) with respect to the disclosure requirements regarding beneficial ownership of Shares, all as if the American Depositary Shares were the Shares represented
thereby, which is deemed to include, inter alia, requirements to make notifications and filings within the required timeframes to the Company, to the Commission, to the French Autorité des Marchés Financiers and any other authorities
in the United States or in the Republic of France. The Company reserves the right to instruct Holders to deliver their American Depositary Shares for cancellation and withdrawal of the Deposited Securities so as to permit the Company to deal
directly with the Holder 

  
 -15- 

 
thereof as a holder of Shares and Holders agree to comply with such instructions. The Depositary agrees to cooperate with the Company in its efforts to inform Holders of the Company’s
exercise of its rights under this paragraph and agrees to consult with, and provide reasonable assistance without risk, liability or expense on the part of the Depositary, to the Company on the manner or manners in which it may enforce such rights
with respect to any Holder. 
 ARTICLE 4. THE DEPOSITED SECURITIES 

SECTION 4.1. Cash Distributions. 

Whenever the Depositary receives any cash dividend or other cash distribution on Deposited Securities, the Depositary shall, subject to the
provisions of Section 4.5, convert that dividend or other distribution into Dollars and distribute the amount thus received (net of the fees and expenses of the Depositary as provided in Section 5.9) to the Owners entitled thereto, in
proportion to the number of American Depositary Shares representing those Deposited Securities held by them respectively; provided, however, that if the Custodian or the Depositary shall be required to withhold and does withhold from
that cash dividend or other cash distribution an amount on account of taxes or other governmental charges, the amount distributed to the Owners of the American Depositary Shares representing those Deposited Securities shall be reduced accordingly.
However, the depositary will not pay any Owner a fraction of one cent, but will round each Owner’s entitlement to the nearest whole cent. 

The Company or its agent will remit to the appropriate governmental agency in each applicable jurisdiction all amounts withheld and owing to
such agency. The Depositary will forward to the Company or its agent such information from its records as the Company may reasonably request to enable the Company or its agent to file necessary reports with governmental agencies. 

If a cash distribution would represent a return of all or substantially all the value of the Deposited Securities underlying American
Depositary Shares, the Depositary may require surrender of those American Depositary Shares and may require payment of or deduct the fee for surrender of American Depositary Shares (whether or not it is also requiring surrender of American
Depositary Shares) as a condition of making that cash distribution. A distribution of that kind shall be a Termination Option Event. 

SECTION 4.2. Distributions Other Than Cash, Shares or Rights. 

Subject to the provisions of Sections 4.11 and 5.9, whenever the Depositary receives any distribution other than a distribution described in
Section 4.1, 4.3 or 4.4 on Deposited Securities (but not in exchange for or in conversion or in lieu of Deposited Securities), the Depositary shall cause the securities or property received by it

  
 -16- 

 
to be distributed to the Owners entitled thereto, after deduction or upon payment of any fees and expenses of the Depositary and any taxes or other governmental charges, in proportion to the
number of American Depositary Shares representing such Deposited Securities held by them respectively, in any manner that the Depositary deems equitable and practicable for accomplishing that distribution (which may be a distribution of depositary
shares representing the securities received); provided, however, that if in the opinion of the Depositary such distribution cannot be made proportionately among the Owners entitled thereto, or if for any other reason (including, but
not limited to, any requirement that the Company or the Depositary withhold an amount on account of taxes or other governmental charges or that securities received must be registered under the Securities Act of 1933 in order to be distributed to
Owners or Holders) the Depositary, after consultation with the Company to the extent practicable, deems such distribution not to be lawful and feasible, the Depositary may adopt such other method as it may deem equitable and practicable for the
purpose of effecting such distribution, including, but not limited to, the public or private sale of the securities or property thus received, or any part thereof, and distribution of the net proceeds of any such sale (net of the fees and expenses
of the Depositary as provided in Section 5.9) to the Owners entitled thereto, all in the manner and subject to the conditions set forth in Section 4.1. The Depositary may withhold any distribution of securities under this Section 4.2
if it has not received satisfactory assurances from the Company that the distribution does not require registration under the Securities Act of 1933. The Depositary may sell, by public or private sale, an amount of securities or other property it
would otherwise distribute under this Section 4.2 that is sufficient to pay its fees and expenses in respect of that distribution. 

If a distribution under this Section 4.2 would represent a return of all or substantially all the value of the Deposited Securities
underlying American Depositary Shares, the Depositary may require surrender of those American Depositary Shares and may require payment of or deduct the fee for surrender of American Depositary Shares (whether or not it is also requiring surrender
of American Depositary Shares) as a condition of making that distribution. A distribution of that kind shall be a Termination Option Event. 

SECTION 4.3. Distributions in Shares. 

Whenever the Depositary receives any distribution on Deposited Securities consisting of a dividend in, or free distribution of, Shares, the
Depositary may deliver to the Owners entitled thereto, in proportion to the number of American Depositary Shares representing those Deposited Securities held by them respectively, an aggregate number of American Depositary Shares representing the
amount of Shares received as that dividend or free distribution, subject to the terms and conditions of the Deposit Agreement with respect to the deposit of Shares and issuance of American Depositary Shares, including withholding of any tax or
governmental charge as provided in Section 4.11 and payment of the fees and expenses of the Depositary as provided in 

  
 -17- 

 
Section 5.9 (and the Depositary may sell, by public or private sale, an amount of the Shares received (or American Depositary Shares representing those Shares) sufficient to pay its fees and
expenses in respect of that distribution). In lieu of delivering fractional American Depositary Shares, the Depositary may sell the amount of Shares represented by the aggregate of those fractions (or American Depositary Shares representing those
Shares) and distribute the net proceeds, all in the manner and subject to the conditions described in Section 4.1. If and to the extent that additional American Depositary Shares are not so delivered and Shares or American Depositary Shares are
not so sold, each American Depositary Share shall thenceforth also represent the additional Shares distributed on the Deposited Securities represented thereby. 

If the Company declares a distribution in which holders of Deposited Securities have a right to elect whether to receive cash, Shares or
other securities or a combination of those things, or a right to elect to have a distribution sold on their behalf, the Depositary may, after consultation with the Company, make that right of election available for exercise by Owners in any manner
the Depositary considers to be lawful and practical. As a condition of making a distribution election right available to Owners, the Depositary may require satisfactory assurances from the Company that doing so does not require registration of any
securities under the Securities Act of 1933. 
 SECTION 4.4. Rights. 

(a) If rights are granted to the Depositary in respect of deposited Shares to purchase additional Shares or other securities, the Company and
the Depositary shall endeavor to consult as to the actions, if any, the Depositary should take in connection with that grant of rights. The Depositary may, to the extent deemed by it to be lawful and practical (i) if requested in writing by the
Company, grant to all or certain Owners rights to instruct the Depositary to purchase the securities to which the rights relate and deliver those securities or American Depositary Shares representing those securities to Owners, (ii) if
requested in writing by the Company, deliver the rights to or to the order of certain Owners, or (iii) sell the rights to the extent practicable and distribute the net proceeds of that sale to Owners entitled to those proceeds. To the extent
rights are not exercised, delivered or disposed of under (i), (ii) or (iii) above, the Depositary shall permit the rights to lapse unexercised. 

(b) If the Depositary will act under (a)(i) above, the Company and the Depositary will enter into a separate agreement setting forth the
conditions and procedures applicable to the particular offering. Upon instruction from an applicable Owner in the form the Depositary specified and upon payment by that Owner to the Depositary of an amount equal to the purchase price of the
securities to be received upon the exercise of the rights, the Depositary shall, on behalf of that Owner, exercise the rights and purchase the securities. The purchased securities shall be delivered to, or as instructed by, the Depositary. The
Depositary shall (i) deposit the purchased Shares under this Deposit Agreement and deliver American Depositary Shares representing 

  
 -18- 

 
those Shares to that Owner or (ii) deliver or cause the purchased Shares or other securities to be delivered to or to the order of that Owner. The Depositary will not act under (a)(i) above
unless the offer and sale of the securities to which the rights relate are registered under the Securities Act of 1933 or the Depositary has received an opinion of United States counsel that is satisfactory to it to the effect that those securities
may be sold and delivered to the applicable Owners without registration under the Securities Act of 1933. 
 (c) If the Depositary will act
under (a)(ii) above, the Company and the Depositary will enter into a separate agreement setting forth the conditions and procedures applicable to the particular offering. Upon (i) the request of an applicable Owner to deliver the rights
allocable to the American Depositary Shares of that Owner to an account specified by that Owner to which the rights can be delivered and (ii) receipt of such documents as the Company and the Depositary agreed to require to comply with
applicable law, the Depositary will deliver those rights as requested by that Owner. 
 (d) If the Depositary will act under (a)(iii)
above, the Depositary will use reasonable efforts to sell the rights in proportion to the number of American Depositary Shares held by the applicable Owners and pay the net proceeds to the Owners otherwise entitled to the rights that were sold, upon
an averaged or other practical basis without regard to any distinctions among such Owners because of exchange restrictions or the date of delivery of any American Depositary Shares or otherwise. 

(e) Payment or deduction of the fees of the Depositary as provided in Section 5.9 and payment or deduction of the expenses of the
Depositary and any applicable taxes or other governmental charges shall be conditions of any delivery of securities or payment of cash proceeds under this Section 4.4. 

(f) The Depositary shall not be responsible for any failure to determine that it may be lawful or feasible to make rights available to or
exercise rights on behalf of Owners in general or any Owner in particular, or to sell rights. 
 SECTION 4.5. Conversion of Foreign
Currency. 
 Whenever the Depositary or the Custodian receives foreign currency, by way of dividends or other distributions or the net
proceeds from the sale of securities, property or rights, and if at the time of the receipt thereof the foreign currency so received can in the judgment of the Depositary be converted on a reasonable basis into Dollars and the resulting Dollars
transferred to the United States, the Depositary shall convert or cause to be converted by sale or in any other manner that it may determine that foreign currency into Dollars, and those Dollars shall be distributed to the Owners entitled thereto. A
cash distribution may be made upon an averaged or other practicable basis without regard to any distinctions among Owners based on exchange restrictions, the date of delivery of any American Depositary Shares or otherwise and shall be net of any
expenses of conversion into Dollars incurred by the Depositary as provided in Section 5.9. 

  
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 If a conversion of foreign currency or the repatriation or distribution of Dollars can be
effected only with the approval or license of any government or agency thereof, the Depositary may, but will not be required to, file an application for that approval or license. 

If the Depositary, after consultation with the Company to the extent practicable, determines that in its judgment any foreign currency
received by the Depositary or the Custodian is not convertible on a reasonable basis into Dollars transferable to the United States, or if any approval or license of any government or agency thereof that is required for such conversion is not filed
or sought by the Depositary, or if any required approval or license is not obtained within a reasonable period as determined by the Depositary, the Depositary may distribute the foreign currency received by the Depositary to, or in its discretion
may hold such foreign currency uninvested and without liability for interest thereon for the respective accounts of, the Owners entitled to receive the same. 

If any conversion of foreign currency, in whole or in part, cannot be effected for distribution to some of the Owners entitled thereto, the
Depositary may in its discretion make that conversion and distribution in Dollars to the extent practicable and permissible to the Owners entitled thereto and may distribute the balance of the foreign currency received by the Depositary to, or hold
that balance uninvested and without liability for interest thereon for the account of, the Owners entitled thereto. 
 The Depositary may
convert currency itself or through any of its affiliates and, in those cases, acts as principal for its own account and not as agent, advisor, broker or fiduciary on behalf of any other person and earns revenue, including, without limitation,
transaction spreads, that it will retain for its own account. The revenue is based on, among other things, the difference between the exchange rate assigned to the currency conversion made under this Deposit Agreement and the rate that the
Depositary or its affiliate receives when buying or selling foreign currency for its own account. The Depositary makes no representation that the exchange rate used or obtained in any currency conversion under this Deposit Agreement will be the most
favorable rate that could be obtained at the time or that the method by which that rate will be determined will be the most favorable to Owners, subject to the Depositary’s obligations under Section 5.3. The methodology used to determine
exchange rates used in currency conversions is available upon request. 
 SECTION 4.6. Fixing of Record Date. 

Whenever a cash dividend, cash distribution or any other distribution is made on Deposited Securities or rights to purchase Shares or other
securities are issued with respect to Deposited Securities (which rights will be delivered to or exercised or sold on behalf of Owners in accordance with Section 4.4) or the Depositary receives notice that a distribution or issuance of that
kind will be made, or whenever the Depositary receives notice that a meeting of holders of Shares will be held in respect of 

  
 -20- 

 
which the Company has requested the Depositary to send a notice under Section 4.7, or whenever the Depositary will assess a fee or charge against the Owners, or whenever the Depositary
causes a change in the number of Shares that are represented by each American Depositary Share, or whenever the Depositary otherwise finds it necessary or convenient, the Depositary shall fix a record date, which shall be the same as, or as near as
practicable to, any corresponding record date set by the Company with respect to Shares, (a) for the determination of the Owners (i) who shall be entitled to receive the benefit of that dividend or other distribution or those rights,
(ii) who shall be entitled to give instructions for the exercise of voting rights at that meeting or (iii) who shall be responsible for that fee or charge or (iv) for any other purpose for which the record date was set, or (b) on
or after which each American Depositary Share will represent the changed number of Shares. Subject to the provisions of Sections 4.1 through 4.5 and to the other terms and conditions of this Deposit Agreement, the Owners on a record date fixed by
the Depositary shall be entitled to receive the amount distributable by the Depositary with respect to such dividend or other distribution or such rights or the net proceeds of sale thereof in proportion to the number of American Depositary Shares
held by them respectively, to give voting instructions or to act in respect of the other matter for which that record date was fixed, or be responsible for that fee or charge, as the case may be. 

SECTION 4.7. Voting of Deposited Shares. 

(a) Upon receipt of notice of any meeting of holders of Shares at which holders of Shares will be entitled to vote, if requested in writing by
the Company, the Depositary shall, as soon as practicable thereafter, Disseminate to the Owners a notice, the form of which shall be in the sole discretion of the Depositary, that shall contain (a) the information contained in the notice
of meeting received by the Depositary from the Company, (b) a statement that the Owners as of the close of business on a specified record date will be entitled, subject to any applicable provision of French law and of the articles of
association or similar documents of the Company, to instruct the Depositary as to the exercise of the voting rights pertaining to the number of Shares represented by their respective American Depositary Shares, c) a statement as to the manner
in which those instructions may be given and (d) the last date on which the Depositary will accept instructions (the “Instruction Cutoff Date”). 

(b) Upon the written request of an Owner of American Depositary Shares, as of the date of the request or, if a record date was specified by
the Depositary, as of that record date, received on or before any Instruction Cutoff Date established by the Depositary, the Depositary may, and if the Depositary sent a notice under the preceding paragraph shall, endeavor, in so far
as practicable, to vote or cause to be voted the amount of deposited Shares represented by those American Depositary Shares in accordance with the instructions set forth in that request. The Depositary shall not vote or attempt to exercise the right
to vote that attaches to the deposited Shares other than in accordance with instructions given by Owners and received by the Depositary. 

  
 -21- 

 (c) There can be no assurance that Owners generally or any Owner in particular will receive
the notice described in paragraph (a) above in time to enable Owners to give instructions to the Depositary prior to the Instruction Cutoff Date. 

(d) In order to give Owners a reasonable opportunity to instruct the Depositary as to the exercise of voting rights relating to Shares, if
the Company will request the Depositary to Disseminate a notice under paragraph (a) above, the Company shall give the Depositary notice of the meeting, details concerning the matters to be voted upon and copies of materials to be made
available to holders of Shares in connection with the meeting not less than 30 days prior to the meeting date, except where under French law the notice period for such meeting is less than 30 days, in which case the Depositary shall upon receipt of
the request use its commercially reasonable efforts to distribute to Owners the material described in the first paragraph of this Section 4.7 and carry out the further actions set forth in this Section 4.7. 

Notwithstanding anything in this Section 4.7 to the contrary, the Depositary and the Company may modify, amend or adopt additional
procedures from time to time as they determine may be necessary or appropriate. 
 Without prejudice to the Depositary’s rights under
Section 2.9, the Depositary will take no action to impair the ability of the Custodian to vote the number of Shares (including the Shares held by the Depositary in registered form) necessary to carry out the instructions of all Owners under
this Section 4.7. 
 SECTION 4.8. Tender and Exchange Offers; Redemption, Replacement or Cancellation of Deposited Securities.

 (a) The Depositary shall not tender any Deposited Securities in response to any voluntary cash tender offer, exchange offer or similar
offer made to holders of Deposited Securities (a “Voluntary Offer”) except when instructed in writing to do so by an Owner surrendering American Depositary Shares and subject to any conditions or procedures the Depositary may
require. 
 (b) If the Depositary receives a written notice that Deposited Securities have been redeemed for cash or otherwise purchased
for cash in a transaction that is mandatory and binding on the Depositary as a holder of those Deposited Securities (a “Redemption”), the Depositary, at the expense of the Company (unless otherwise agreed between the Company and the
Depositary), shall (i) if required, surrender Deposited Securities that have been redeemed to the issuer of those securities or its agent on the redemption date, (ii) Disseminate a notice to Owners (A) notifying them of that
Redemption, (B) calling for surrender of a corresponding number of American Depositary Shares and (C) notifying them that the called American Depositary Shares have been converted into a right only to receive the money received by the
Depositary upon that Redemption and those net proceeds shall be the Deposited Securities to which Owners of those converted American Depositary Shares shall be entitled upon surrenders 

  
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of those American Depositary Shares in accordance with Section 2.5 or 6.2 and (iii) distribute the money received upon that Redemption to the Owners entitled to it upon surrender by
them of called American Depositary Shares in accordance with Section 2.5 (and, for the avoidance of doubt, Owners shall not be entitled to receive that money under Section 4.1 or 4.2). If the Redemption affects less than all the Deposited
Securities, the Depositary shall call for surrender a corresponding portion of the outstanding American Depositary Shares and only those American Depositary Shares will automatically be converted into a right to receive the net proceeds of the
Redemption. The Depositary shall allocate the American Depositary Shares converted under the preceding sentence among the Owners pro-rata to their respective holdings of American Depositary Shares immediately prior to the Redemption, except
that the allocations may be adjusted so that no fraction of a converted American Depositary Share is allocated to any Owner. A Redemption of all or substantially all of the Deposited Securities shall be a Termination Option Event. 

(c) If the Depositary is notified of or there occurs any change in nominal value or any subdivision, combination or any other
reclassification of the Deposited Securities or any recapitalization, reorganization, sale of assets substantially as an entirety, merger or consolidation affecting the issuer of the Deposited Securities or to which it is a party that is mandatory
and binding on the Depositary as a holder of Deposited Securities and as a result securities or other property have been or will be delivered in exchange, conversion, replacement or in lieu of, Deposited Securities (a
“Replacement”), then (i) the Depositary shall, if required surrender the old Deposited Securities affected by that Replacement of Shares and hold, as new Deposited Securities under this Deposit Agreement, the new securities or
other property delivered to it in that Replacement. However, the Depositary may elect to sell those new Deposited Securities if in the opinion of the Depositary, after consultation with the Company or its successor entity to the extent
practicable, it is not lawful or not practical for it to hold those new Deposited Securities under this Deposit Agreement because those new Deposited Securities may not be distributed to Owners without registration under the Securities Act of 1933
or for any other reason, at public or private sale, at such places and on such terms as it deems proper and proceed as if those new Deposited Securities had been Redeemed under paragraph (b) above. A Replacement shall be a Termination Option
Event. 
 (d) In the case of a Replacement where the new Deposited Securities will continue to be held under this Deposit Agreement,
the Depositary may call for the surrender of outstanding Receipts to be exchanged for new Receipts specifically describing the new Deposited Securities and the number of those new Deposited Securities represented by each American Depositary Share.
If the number of Shares represented by each American Depositary Share decreases as a result of a Replacement, the Depositary may, after consultation with the Company to the extent practicable, call for surrender of the American Depositary Shares to
be exchanged on a mandatory basis for a lesser number of American Depositary Shares and may sell American Depositary Shares to the extent necessary to avoid distributing fractions of American Depositary Shares in that exchange and distribute the net
proceeds of that sale to the Owners entitled to them. 

  
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 (e) If there are no Deposited Securities with respect to American Depositary Shares, including
if the Deposited Securities are cancelled, or the Deposited Securities with respect to American Depositary Shares have become apparently worthless, the Depositary may call for surrender of those American Depositary Shares or may cancel those
American Depositary Shares, upon notice to Owners, and a Termination Option Event occurs. 
 SECTION 4.9. Reports. 

The Depositary shall make available for inspection by Owners at its Office any reports and communications, including any proxy solicitation
material, received from the Company which are both (a) received by the Depositary as the holder of the Deposited Securities and (b) made generally available to the holders of those Deposited Securities by the Company. The Company shall
furnish reports and communications, including any proxy soliciting material to which this Section applies, to the Depositary in English, to the extent those materials are required to be translated into English pursuant to any regulations of the
Commission. 
 SECTION 4.10. Lists of Owners. 

Upon written request by the Company, the Depositary shall, at the expense of the Company (unless otherwise agreed between the Company and the
Depositary), furnish to it a list, as of a recent date, of the names, addresses and American Depositary Share holdings of all Owners. 

SECTION 4.11. Withholding. 

In the event that the Depositary determines that any distribution received or to be made by the Depositary (including Shares and rights to
subscribe therefor) is subject to any tax or other governmental charge that the Depositary is obligated to withhold, the Depositary may sell, by public or private sale, all or a portion of the distributed property (including Shares and rights to
subscribe therefor) in the amounts and manner the Depositary deems necessary and practicable to pay those taxes or charges, and the Depositary shall distribute the net proceeds of that sale, after deduction of those taxes or charges, to the Owners
entitled thereto in proportion to the number of American Depositary Shares held by them respectively. 
 None of the Company, the
Depositary or the Custodian shall be liable for the failure by any Holder or Owner to obtain the benefits of credits on the basis of any tax withheld or paid against such Holder’s or Owner’s tax liability. 

  
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 ARTICLE 5. THE DEPOSITARY, THE CUSTODIANS AND THE COMPANY 

SECTION 5.1. Maintenance of Office and Transfer Books by the Depositary. 

Until termination of this Deposit Agreement in accordance with its terms, the Depositary shall maintain facilities for the execution and
delivery, registration, registration of transfers and surrender of American Depositary Shares in accordance with the provisions of this Deposit Agreement. 

The Depositary shall keep books for the registration of American Depositary Shares, which shall be open for inspection by the Owners at the
Depositary’s Office during regular business hours, provided that such inspection is not for the purpose of communicating with Owners in the interest of a business or object other than the business of the Company or a matter related to
this Deposit Agreement or the American Depositary Shares. 
 The Depositary may close the transfer books, at any time or from time to time,
when deemed expedient by it in connection with the performance of its duties under this Deposit Agreement (whereupon it shall notify the Company as promptly as practicable of any closure that is outside the ordinary course of business). 

Subject to the provisions of Section 5.4, if the Company lists any American Depositary Shares on one or more stock exchanges in the
United States, the Depositary shall act as Registrar or appoint a Registrar or one or more co-registrars for registry of those American Depositary Shares in accordance with any requirements of that exchange or
those exchanges. The Depositary shall notify the Company of any such appointment. 
 SECTION 5.2. Prevention or Delay in Performance by
the Depositary or the Company. 
 Neither the Depositary nor the Company nor any of their respective directors, employees, agents or
affiliates shall incur any liability to any Owner or Holder (i) if by reason of any provision of any present or future law or regulation of the United States or any other country, or of any governmental or regulatory authority or stock
exchange, or by reason of any provision, present or future, of the articles of association or similar document of the Company, or by reason of any provision of any securities issued or distributed by the Company, or any offering or distribution
thereof, or by reason of any act of God or war or terrorism or other circumstances beyond its control, the Depositary or the Company is prevented from, forbidden to or delayed in, or could be subject to any civil or criminal penalty on account of
doing or performing and therefore does not do or perform, any act or thing that, by the terms of this Deposit Agreement or the Deposited Securities, it is provided shall be done or performed, (ii) by reason of any exercise of, or failure to
exercise, any discretion provided for in this Deposit Agreement (including any 

  
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determination by the Depositary to take, or not take, any action that this Deposit Agreement provides the Depositary may take), (iii) for the inability of any Owner or Holder to benefit from
any distribution, offering, right or other benefit that is made available to holders of Deposited Securities but is not, under the terms of this Deposit Agreement, made available to Owners or Holders, or (iv) for any special, consequential,
indirect or punitive damages for any breach of the terms of this Deposit Agreement. Where, by the terms of a distribution to which Section 4.1, 4.2 or 4.3 applies, or an offering to which Section 4.4 applies, or for any other reason, that
distribution or offering may not be made available to Owners, and the Depositary may not dispose of that distribution or offering on behalf of Owners and make the net proceeds available to Owners, then the Depositary shall not make that distribution
or offering available to Owners, and shall allow any rights, if applicable, to lapse. 
 SECTION 5.3. Obligations of the Depositary and
the Company. 
 The Company assumes no obligation nor shall it be subject to any liability under this Deposit Agreement to any Owner or
Holder or any other persons (other than the Depositary), except that the Company agrees to perform its obligations specifically set forth in this Deposit Agreement without negligence or bad faith. 

The Depositary assumes no obligation nor shall it be subject to any liability under this Deposit Agreement to any Owner or Holder (including,
without limitation, liability with respect to the validity or worth of the Deposited Securities), except that the Depositary agrees to perform its obligations specifically set forth in this Deposit Agreement without negligence or bad faith. 

Neither the Depositary nor the Company shall be under any obligation to appear in, prosecute or defend any action, suit or other proceeding
in respect of any Deposited Securities or in respect of the American Depositary Shares on behalf of any Owner or Holder or any other person. 

Each of the Depositary and the Company may rely, and shall be protected in relying upon, any written notice, request, direction or other
document believed by it to be genuine and to have been signed or presented by the proper party or parties. 
 Neither the Depositary nor
the Company, nor any of their respective affiliates (as such term is defined in Regulation C under the Securities Act of 1933) or agents, shall be liable for any action or non-action by it in reliance upon the advice of or information from legal
counsel, accountants, any person presenting Shares for deposit, any Owner or any other person believed by it in good faith to be competent to give such advice or information. 

The Depositary shall not be liable for any acts or omissions made by a successor depositary whether in connection with a previous act or
omission of the Depositary or in connection with any matter arising wholly after the removal or 

  
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resignation of the Depositary, provided that in connection with the issue out of which such potential liability arises the Depositary performed its obligations without negligence or bad faith
while it acted as Depositary. 
 The Depositary shall not be liable for the acts or omissions of any securities depository, clearing agency
or settlement system in connection with or arising out of book-entry settlement of American Depositary Shares or Deposited Securities or otherwise. 

In the absence of bad faith on its part, the Depositary shall not be responsible for any failure to carry out any instructions to vote any of
the Deposited Securities, or for the manner in which any such vote is cast or the effect of any such vote. 
 Neither the Company nor the
Depositary shall have any duty to make any determination or provide any information as to the tax status of the Company or any liability for any tax consequences that may be incurred by Owners or Holders as a result of owning or holding American
Depositary Shares, including without limitation, tax consequences resulting from the Company (or any of its subsidiaries) being treated as a “Passive Foreign Investment Company” (“PFIC”) (in each case as defined in the
U.S. Internal Revenue Code and the regulations issued thereunder) or otherwise. The Company may have been in the past and may be in the future a PFIC for U.S. Federal income tax purposes. Owners must consult their own tax advisers as to the
potential application of the PFIC rules. 
 No disclaimer of liability under the Securities Act of 1933 is intended by any provision of
this Deposit Agreement. 
 SECTION 5.4. Resignation and Removal of the Depositary. 

The Depositary may at any time resign as Depositary hereunder by written notice of its election so to do delivered to the Company, to become
effective upon the appointment of a successor depositary and its acceptance of that appointment as provided in this Section. The effect of resignation if a successor depositary is not appointed is provided for in Section 6.2. 

The Depositary may at any time be removed by the Company by 120 days’ prior written notice of that removal, to become effective upon the
later of (i) the 120th day after delivery of the notice to the Depositary and (ii) the appointment of a successor depositary and its acceptance of its appointment as provided in this Section. 

In case at any time the Depositary acting hereunder shall resign or be removed, the Company shall use its best efforts to appoint a successor
depositary, which shall be a bank or trust company having an office in the Borough of Manhattan, The City of New York. Every successor depositary shall execute and deliver to its predecessor and to the Company an instrument in writing accepting its
appointment hereunder, and 

  
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thereupon such successor depositary, without any further act or deed, shall become fully vested with all the rights, powers, duties and obligations of its predecessor; but such predecessor,
nevertheless, upon payment of all sums due it and on the written request of the Company shall execute and deliver an instrument transferring to such successor all rights and powers of such predecessor hereunder, shall duly assign, transfer and
deliver all right, title and interest in the Deposited Securities to such successor and shall deliver to such successor a list of the Owners of all outstanding American Depositary Shares. Any such successor depositary shall promptly mail notice of
its appointment to the Owners. 
 Any corporation or other entity into or with which the Depositary may be merged or consolidated shall be
the successor of the Depositary without the execution or filing of any document or any further act. 
 SECTION 5.5. The Custodians.

 The Custodian shall be subject at all times and in all respects to the directions of the Depositary and shall be responsible solely to
it. The Depositary in its discretion may at any time appoint a substitute or additional custodian or custodians, each of which shall thereafter be one of the Custodians under this Deposit Agreement. If the Depositary receives notice that a Custodian
is resigning and, upon the effectiveness of that resignation there would be no Custodian acting under this Deposit Agreement, the Depositary shall, as promptly as practicable after receiving that notice, appoint a substitute custodian or custodians,
each of which shall thereafter be a Custodian under this Deposit Agreement. The Depositary shall require any Custodian that resigns or is removed to deliver all Deposited Securities held by it to another Custodian. 

SECTION 5.6. Notices and Reports. 

On or before the first date on which the Company gives notice, by publication or otherwise, of any meeting of holders of Shares or other
Deposited Securities, or of any adjourned meeting of those holders, or of the taking of any action in respect of any cash or other distributions or the granting of any rights, the Company agrees to transmit to the Depositary and the Custodian a copy
of the notice thereof in English but otherwise in the form given or to be given to holders of Shares or other Deposited Securities. 
 The
Company will arrange for the translation into English, if not already in English, to the extent required pursuant to any regulations of the Commission, and the prompt transmittal by the Company to the Depositary and the Custodian of all notices and
any other reports and communications which are made generally available by the Company to holders of its Shares. If requested in writing by the Company, the Depositary will Disseminate, at the Company’s expense unless otherwise agreed between
the Company and the Depositary, those notices, reports and communications to all Owners or otherwise make them available to Owners in a manner that the Company 

  
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specifies as substantially equivalent to the manner in which those communications are made available to holders of Shares and compliant with the requirements of any securities exchange on which
the American Depositary Shares are listed. The Company will timely provide the Depositary with the quantity of such notices, reports, and communications, as requested by the Depositary from time to time, in order for the Depositary to effect that
Dissemination. 
 The Company represents that as of the date of this Deposit Agreement, the statements in Article 11 of the Receipt with
respect to the Company’s obligation to file periodic reports under the United States Securities Exchange Act of 1934, as amended, are true and correct. The Company agrees to promptly notify the Depositary upon becoming aware of any change in
the truth of any of those statements. 
 SECTION 5.7. Distribution of Additional Shares, Rights, etc. 

If the Company or any affiliate of the Company determines to make any issuance or distribution of (1) additional Shares, (2) rights
to subscribe for Shares, (3) securities convertible into Shares, or (4) rights to subscribe for such securities (each a “Distribution”), the Company shall notify the Depositary in writing in English as promptly as
practicable and in any event before the Distribution starts and, if requested in writing by the Depositary, the Company shall promptly furnish to the Depositary either (i) evidence satisfactory to the Depositary that the Distribution is
registered under the Securities Act of 1933 or (ii) a written opinion from U.S. counsel for the Company that is reasonably satisfactory to the Depositary, stating that the Distribution does not require, or, if made in the United States, would
not require, registration under the Securities Act of 1933. 
 The Company agrees with the Depositary that neither the Company nor any
company controlled by, controlling or under common control with the Company will at any time deposit any Shares that, at the time of deposit, are Restricted Securities. 

SECTION 5.8. Indemnification. 

The Company agrees to indemnify the Depositary, its directors, employees, agents and affiliates and each Custodian against, and hold each of
them harmless from, any liability or expense (including, but not limited to any reasonable fees and expenses incurred in seeking, enforcing or collecting such indemnity and the fees and expenses of counsel) which may arise out of or in connection
with (a) any registration with the Commission of American Depositary Shares or Deposited Securities or the offer or sale thereof in the United States or (b) acts performed or omitted, pursuant to the provisions of or in connection with
this Deposit Agreement and the American Depositary Shares, as the same may be amended, modified or supplemented from time to time, (i) by either the Depositary or a Custodian or their respective directors, employees, agents and affiliates,
except for any liability or expense arising out of the negligence or bad faith of either of them, or (ii) by the Company or any of its directors, employees, agents and affiliates. 

  
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 The Depositary agrees to indemnify the Company, its directors, officers, employees, agents and
affiliates and hold them harmless from any liability or expense (including, but not limited to, the reasonable fees and expenses of counsel) which may arise out of acts performed or omitted by the Depositary or any Custodian or their respective
directors, employees, agents and affiliates due to their negligence or bad faith. 
 The obligations set forth in this Section 5.8
shall survive the termination of this Deposit Agreement and the succession or substitution of any party hereto. 
 Any person seeking
indemnification hereunder (an “indemnified person”) shall notify the person from whom it is seeking indemnification (the “indemnifying person”) of the commencement of any indemnifiable action or claim promptly after
such indemnified person becomes aware of such commencement (provided that the failure to make such notification shall not affect such indemnified person’s rights to seek indemnification except to the extent the indemnifying person is materially
prejudiced by such failure) and shall consult in good faith with the indemnifying person as to the conduct of the defense of such action or claim that may give rise to an indemnity hereunder, which defense shall be reasonable in the circumstances.
No indemnified person shall compromise or settle any action or claim that may give rise to an indemnity hereunder without the consent of the indemnifying person, which consent shall not be unreasonably withheld. 

SECTION 5.9. Charges of Depositary. 

The Company agrees to pay the fees and out-of-pocket expenses of the Depositary and those of any Registrar only in accordance with agreements
in writing entered into between the Depositary and the Company from time to time or to the extent that the Company is a depositor of Shares or an Owner. 

The following charges shall be incurred by any party depositing or withdrawing Shares or by any party surrendering American Depositary Shares
or to whom American Depositary Shares are issued (including, without limitation, issuance pursuant to a stock dividend or stock split declared by the Company or an exchange of stock regarding the American Depositary Shares or Deposited Securities or
a delivery of American Depositary Shares pursuant to Section 4.3), or by Owners, as applicable: (1) taxes and other governmental charges, (2) such registration fees as may from time to time be in effect for the registration of
transfers of Shares generally on the Share register of the Company or Foreign Registrar and applicable to transfers of Shares to or from the name of the Depositary or its nominee or the Custodian or its nominee on the making of deposits or
withdrawals hereunder, (3) such cable (including SWIFT) and facsimile transmission fees and expenses as are expressly provided in this Deposit Agreement, (4) such expenses as are incurred by the Depositary in the conversion of foreign
currency 

  
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pursuant to Section 4.5, (5) a fee of $5.00 or less per 100 American Depositary Shares (or portion thereof) for the delivery of American Depositary Shares pursuant to Section 2.3,
4.3 or 4.4 and the surrender of American Depositary Shares pursuant to Section 2.5 or 6.2, (6) a fee of $.05 or less per American Depositary Share (or portion thereof) for any cash distribution made pursuant to this Deposit Agreement,
including, but not limited to Sections 4.1 through 4.4 and Section 4.8, (7) a fee for the distribution of securities pursuant to Section 4.2 or of rights pursuant to Section 4.4 (where the Depositary will not exercise or sell
those rights on behalf of Owners), such fee being in an amount equal to the fee for the execution and delivery of American Depositary Shares referred to above which would have been charged as a result of the deposit of such securities under this
Deposit Agreement (for purposes of this item 7 treating all such securities as if they were Shares) but which securities are instead distributed by the Depositary to Owners, (8) in addition to any fee charged under item 6 above, a fee of $.05
or less per American Depositary Share (or portion thereof) per annum for depositary services, which will be payable as provided in item 9 below, and (9) any other charges payable by the Depositary or the Custodian, any of the Depositary’s
or Custodian’s agents or the agents of the Depositary’s or Custodian’s agents, in connection with the servicing of Shares or other Deposited Securities (which charges shall be assessed against Owners as of the date or dates set by the
Depositary in accordance with Section 4.6 and shall be payable at the sole discretion of the Depositary by billing those Owners for those charges or by deducting those charges from one or more cash dividends or other cash distributions). 

The Depositary may collect any of its fees by deduction from any cash distribution payable, or by selling a portion of any securities to be
distributed, to Owners that are obligated to pay those fees. 
 In performing its duties under this Deposit Agreement, the Depositary may
use brokers, dealers, foreign currency dealers or other service providers that are owned by or affiliated with the Depositary and that may earn or share fees, spreads or commissions. 

The Depositary, subject to Section 2.9, may own and deal in any class of securities of the Company and its affiliates and in American
Depositary Shares. 
 SECTION 5.10. Retention of Depositary Documents. 

The Depositary is authorized to destroy those documents, records, bills and other data compiled during the term of this Deposit Agreement at
the times permitted by the laws or regulations governing the Depositary. 
 SECTION 5.11. Exclusivity. 

Without prejudice to the Company’s rights under Section 5.4, the Company agrees not to appoint any other depositary for issuance of
depositary shares, depositary receipts or any similar securities or instruments (for the avoidance of doubt, other than instruments or securities issued directly by the Company) in the United States so long as The Bank of New York Mellon is acting
as Depositary under this Deposit Agreement. 

  
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 ARTICLE 6. AMENDMENT AND TERMINATION 

SECTION 6.1. Amendment. 

The form of the Receipts and any provisions of this Deposit Agreement may at any time and from time to time be amended by agreement between
the Company and the Depositary without the consent of Owners or Holders in any respect that they may deem necessary or desirable. Any amendment that would impose or increase any fees or charges (other than taxes and other governmental charges,
registration fees, cable, telex or facsimile transmission costs, delivery costs or other such expenses), or that would otherwise prejudice any substantial existing right of Owners, shall, however, not become effective as to outstanding American
Depositary Shares until the expiration of 30 days after notice of that amendment has been Disseminated to the Owners of outstanding American Depositary Shares. Every Owner and Holder, at the time any amendment so becomes effective, shall be deemed,
by continuing to hold American Depositary Shares or any interest therein, to consent and agree to that amendment and to be bound by the Deposit Agreement as amended thereby. Upon the effectiveness of an amendment to the form of Receipt, including a
change in the number of Shares represented by each American Depositary Share, the Depositary may call for surrender of Receipts to be replaced with new Receipts in the amended form or call for surrender of American Depositary Shares to effect that
change of ratio. In no event shall any amendment impair the right of the Owner to surrender American Depositary Shares and receive delivery of the Deposited Securities represented thereby, except in order to comply with mandatory provisions of
applicable law. 
 SECTION 6.2. Termination. 

(a) The Company may terminate this Deposit Agreement by notice to the Depositary. The Depositary may terminate this Deposit Agreement if
(i) at any time 60 days shall have expired after the Depositary delivered to the Company a written resignation notice and a successor depositary has not been appointed and accepted its appointment as provided in Section 5.4, (ii) an
Insolvency Event or Delisting Event occurs with respect to the Company or (iii) a Termination Option Event has occurred or will occur. If a termination of the Deposit Agreement has been initiated by the Company or the Depositary, the Depositary
shall Disseminate a notice of termination to the Owners of all American Depositary Shares then outstanding setting a date for termination (the “Termination Date”), which shall be at least 90 days after the date of that notice, and
this Deposit Agreement shall terminate on that Termination Date. 
 (b) After the Termination Date, the Company shall be discharged from
all obligations under this Deposit Agreement except for its obligations to the Depositary under Sections 5.8 and 5.9. 
 (c) At any time
after the Termination Date, the Depositary may sell the Deposited Securities then held under this Deposit Agreement and may thereafter hold 

  
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uninvested the net proceeds of any such sale, together with any other cash then held by it hereunder, unsegregated and without liability for interest, for the pro rata benefit of the Owners of
American Depositary Shares that remain outstanding, and those Owners will become general creditors of the Depositary with respect to those net proceeds. After making that sale, the Depositary shall be discharged from all obligations under this
Deposit Agreement, except (i) to account for the net proceeds and other cash (after deducting, in each case, the fee of the Depositary for the surrender of American Depositary Shares, any expenses for the account of the Owner of such
American Depositary Shares in accordance with the terms and conditions of this Deposit Agreement and any applicable taxes or governmental charges) and (ii) for its obligations under Section 5.8 and (iii) to act as provided in the
paragraph (d) below. 
 (d) After the Termination Date, the Depositary shall continue to receive dividends and other
distributions pertaining to Deposited Securities (that have not been sold), may sell rights and other property as provided in this Deposit Agreement and shall deliver Deposited Securities (or sale proceeds) upon surrender of American Depositary
Shares (after payment or upon deduction, in each case, of the fee of the Depositary for the surrender of American Depositary Shares, any expenses for the account of the Owner of those American Depositary Shares in accordance with the terms and
conditions of this Deposit Agreement and any applicable taxes or governmental charges). However, after the Termination Date, (i) the Depositary may refuse to accept surrenders of American Depositary Shares for the purpose of withdrawal
of Deposited Securities (that have not been sold) if in its judgment the requested withdrawal would interfere with its efforts to sell the Deposited Securities, (ii) the Depositary will not be required to deliver cash proceeds of the sale of
Deposited Securities until all Deposited Securities have been sold and (iii) the Depositary may discontinue the registration of transfers of American Depositary Shares and suspend the distribution of dividends and other distributions on
Deposited Securities to the Owners and need not give any further notices or perform any further acts under this Deposit Agreement except as provided in this Section. 

ARTICLE 7. MISCELLANEOUS 

SECTION 7.1. Counterparts; Signatures. 

This Deposit Agreement may be executed in any number of counterparts, each of which shall be deemed an original and all of those counterparts
shall constitute one and the same instrument. Copies of this Deposit Agreement shall be filed with the Depositary and the Custodians and shall be open to inspection by any Owner or Holder during regular business hours. 

Any manual signature on this Deposit Agreement that is faxed, scanned or photocopied, and any electronic signature valid under the Electronic
Signatures in Global and National Commerce Act, 15 U.S.C. § 7001, et. seq., shall for all purposes have the same validity, legal effect and admissibility in evidence as an original manual signature, and the parties hereby waive any
objection to the contrary. 

  
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 SECTION 7.2. No Third Party Beneficiaries. 

This Deposit Agreement is for the exclusive benefit of the parties and shall not be deemed to give any legal or equitable right, remedy or
claim whatsoever to any other person. 
 SECTION 7.3. Severability. 

In case any one or more of the provisions contained in this Deposit Agreement or in a Receipt should be or become invalid, illegal or
unenforceable in any respect, the validity, legality and enforceability of the remaining provisions contained in this Deposit Agreement or that Receipt shall in no way be affected, prejudiced or disturbed thereby. 

SECTION 7.4. Owners and Holders as Parties; Binding Effect. 

The Owners and Holders from time to time shall be parties to this Deposit Agreement and shall be bound by all of the terms and conditions of
this Deposit Agreement and of the Receipts by acceptance of American Depositary Shares or any interest therein. 
 SECTION 7.5.
Notices. 
 Any and all notices to be given to the Company shall be in writing and shall be deemed to have been duly given if
personally delivered or sent by domestic first class or international air mail or air courier or sent by facsimile transmission or email attaching a pdf or similar bit-mapped image of a signed writing, provided that receipt of the facsimile
transmission or email has been confirmed by the recipient, addressed to ERYTECH Pharma S.A., 60 avenue Rockefeller, Bâtiment Adénine, 4ème étage, 69008 Lyon, France, Attention: Gil Beyen, or any other place to which the
Company may have transferred its principal office with notice to the Depositary. 
 Any and all notices to be given to the Depositary shall
be in writing and shall be deemed to have been duly given if in English and personally delivered or sent by first class domestic or international air mail or air courier or sent by facsimile transmission or email attaching a pdf or similar
bit-mapped image of a signed writing, addressed to The Bank of New York Mellon, 101 Barclay Street, New York, New York 10286, Attention: Depositary Receipt Administration, or any other place to which the Depositary may have transferred its
Office with notice to the Company. 
 Delivery of a notice to the Company or Depositary by mail or air courier shall be deemed effected
when deposited, postage prepaid, in a post-office letter box or 

  
 -34- 

 
received by an air courier service. Delivery of a notice to the Company or Depositary sent by facsimile transmission or email shall be deemed effected when the recipient acknowledges receipt of
that notice. 
 A notice to be given to an Owner shall be deemed to have been duly given when Disseminated to that Owner. Dissemination in
paper form will be effective when personally delivered or sent by first class domestic or international air mail or air courier, addressed to that Owner at the address of that Owner as it appears on the transfer books for American Depositary Shares
of the Depositary, or, if that Owner has filed with the Depositary a written request that notices intended for that Owner be mailed to some other address, at the address designated in that request. Dissemination in electronic form will be effective
when sent in the manner consented to by the Owner to the electronic address most recently provided by the Owner for that purpose. 
 SECTION
7.6. Appointment of Agent for Service of Process; Submission to Jurisdiction; Jury Trial Waiver. 
 The Company hereby
(i) designates and appoints the person named in Exhibit A to this Deposit Agreement, located in the United States, as the Company’s U.S. registered agent upon which process may be served in any suit or proceeding arising out of or relating
to the Shares or Deposited Securities, the American Depositary Shares, the Receipts or this Deposit Agreement (a “Proceeding”), (ii) consents and submits to the jurisdiction of any state or federal court in the State of New York in
which any Proceeding may be instituted and (iii) agrees that service of process upon said U.S. registered agent shall be deemed in every respect effective service of process upon the Company in any Proceeding. The Company agrees to deliver to
the Depositary, upon the execution and delivery of this Deposit Agreement, a written acceptance by the above-named agent of its appointment as process agent. The Company further agrees to take any and all action, including the filing of any and all
such documents and instruments, as may be necessary to continue that designation and appointment in full force and effect, or to appoint and maintain the appointment of another process agent located in the United States as required above, and to
deliver to the Depositary a written acceptance by that agent of that appointment, for so long as any American Depositary Shares or Receipts remain outstanding or this Deposit Agreement remains in force. In the event the Company fails to maintain the
designation and appointment of a process agent in the United States in full force and effect, the Company hereby waives personal service of process upon it and consents that a service of process in connection with a Proceeding may be made by
certified or registered mail, return receipt requested, directed to the Company at its address last specified for notices under this Deposit Agreement, and service so made shall be deemed completed five (5) days after the same shall have been
so mailed. 
 EACH PARTY TO THIS DEPOSIT AGREEMENT (INCLUDING, FOR AVOIDANCE OF DOUBT, EACH OWNER AND HOLDER) HEREBY

  
 -35- 

 
IRREVOCABLY WAIVES, TO THE FULLEST EXTENT PERMITTED BY APPLICABLE LAW, ANY RIGHT IT MAY HAVE TO A TRIAL BY JURY IN ANY SUIT, ACTION OR PROCEEDING AGAINST THE COMPANY AND/OR THE DEPOSITARY
DIRECTLY OR INDIRECTLY ARISING OUT OF OR RELATING TO THE SHARES OR OTHER DEPOSITED SECURITIES, THE AMERICAN DEPOSITARY SHARES OR THE RECEIPTS, THIS DEPOSIT AGREEMENT OR ANY TRANSACTION CONTEMPLATED HEREIN OR THEREIN, OR THE BREACH HEREOF OR THEREOF,
INCLUDING, WITHOUT LIMITATION, ANY QUESTION REGARDING EXISTENCE, VALIDITY OR TERMINATION (WHETHER BASED ON CONTRACT, TORT OR ANY OTHER THEORY). 

SECTION 7.7. Waiver of Immunities. 

To the extent that the Company or any of its properties, assets or revenues may have or may hereafter become entitled to, or have attributed
to it, any right of immunity, on the grounds of sovereignty or otherwise, from any legal action, suit or proceeding, from the giving of any relief in any respect thereof, from setoff or counterclaim, from the jurisdiction of any court, from service
of process, from attachment upon or prior to judgment, from attachment in aid of execution or judgment, or from execution of judgment, or other legal process or proceeding for the giving of any relief or for the enforcement of any judgment, in any
jurisdiction in which proceedings may at any time be commenced, with respect to its obligations, liabilities or any other matter under or arising out of or in connection with the Shares or Deposited Securities, the American Depositary Shares, the
Receipts or this Deposit Agreement, the Company, to the fullest extent permitted by law, hereby irrevocably and unconditionally waives, and agrees not to plead or claim, any immunity of that kind and consents to relief and enforcement as provided
above. 
 SECTION 7.8. Governing Law. 

This Deposit Agreement and the Receipts shall be interpreted in accordance with and all rights hereunder and thereunder and provisions hereof
and thereof shall be governed by the laws of the State of New York. 

  
 -36- 

 IN WITNESS WHEREOF, ERYTECH PHARMA S.A. and THE BANK OF NEW YORK MELLON have duly executed this
Deposit Agreement as of the day and year first set forth above and all Owners and Holders shall become parties hereto upon acceptance by them of American Depositary Shares or any interest therein. 

 

			
	ERYTECH PHARMA S.A.
		
	By:	 	  

	Name:	 	
	Title:	 	
	
	 THE BANK OF NEW YORK MELLON,

  as Depositary

		
	By:	 	  

	Name:	 	
	Title:	 	

  
 -37- 

 EXHIBIT A 
  

							
		  				  	AMERICAN DEPOSITARY SHARES
		  				  	(Each American Depositary Share represents
		  				  	one deposited Share)

 THE BANK OF NEW YORK MELLON 

AMERICAN DEPOSITARY RECEIPT 
 FOR
ORDINARY SHARES OF 
 ERYTECH PHARMA S.A. 

(INCORPORATED UNDER THE LAWS OF FRANCE) 

The Bank of New York Mellon, as depositary (hereinafter called the “Depositary”), hereby certifies that
                                         , or
registered assigns IS THE OWNER OF                      

AMERICAN DEPOSITARY SHARES 
 representing
deposited ordinary shares (herein called “Shares”) of ERYTECH Pharma S.A., incorporated under the laws of France (herein called the “Company”). At the date hereof, each American Depositary Share represents one Share
deposited or subject to deposit under the Deposit Agreement (as such term is hereinafter defined) with a custodian for the Depositary (herein called the “Custodian”) that, as of the date of the Deposit Agreement, was
Société Générale located in Paris. The Depositary’s Office is located at a different address than its principal executive office. Its Office is located at 101 Barclay Street, New York, N.Y. 10286, and its principal
executive office is located at One Wall Street, New York, N.Y. 10286. 
 THE DEPOSITARY’S OFFICE ADDRESS IS 

101 BARCLAY STREET, NEW YORK, N.Y. 10286 

  
 A-1 

	1.	THE DEPOSIT AGREEMENT. 

 This American Depositary Receipt is one of an issue (herein called
“Receipts”), all issued and to be issued upon the terms and conditions set forth in the Amended and Restated Deposit Agreement dated as of             , 2017 (herein called
the “Deposit Agreement”) among the Company, the Depositary, and all Owners and Holders from time to time of American Depositary Shares issued thereunder, each of whom by accepting American Depositary Shares agrees to become a party
thereto and become bound by all the terms and conditions thereof. The Deposit Agreement sets forth the rights of Owners and Holders and the rights and duties of the Depositary in respect of the Shares deposited thereunder and any and all other
securities, property and cash from time to time received in respect of those Shares and held thereunder (those Shares, securities, property, and cash are herein called “Deposited Securities”). Copies of the Deposit Agreement are on
file at the Depositary’s Office in New York City and at the office of the Custodian. 
 The statements made on the face and reverse of
this Receipt are summaries of certain provisions of the Deposit Agreement and are qualified by and subject to the detailed provisions of the Deposit Agreement, to which reference is hereby made. Capitalized terms defined in the Deposit Agreement and
not defined herein shall have the meanings set forth in the Deposit Agreement. 
  

	2.	SURRENDER OF RECEIPTS AND WITHDRAWAL OF SHARES. 

 Upon surrender at the Depositary’s Office
of American Depositary Shares for the purpose of withdrawal of the Deposited Securities represented thereby and payment of the fee of the Depositary for the surrender of American Depositary Shares as provided in Section 5.9 of the Deposit
Agreement and payment of all taxes and governmental charges payable in connection with that surrender and withdrawal of the Deposited Securities, and subject to the terms and conditions of this Deposit Agreement, the Owner of those American
Depositary Shares shall be entitled to delivery (to the extent delivery can then be lawfully and practicably made), to or as instructed by that Owner, of the amount of Deposited Securities at the time represented by those American Depositary Shares.
That delivery will be made, at the office of the Custodian, except that, at the request, risk and expense of the surrendering Owner, and for the account of that Owner, the Depositary shall direct the Custodian to forward any cash or other
property comprising, and forward a certificate or certificates, if applicable, and other proper documents of title, if any, for, the Deposited Securities represented by the surrendered American Depositary Shares to the Depositary for delivery at the
Depositary’s Office or to another address specified in the order received from the surrendering Owner. The Depositary shall direct the Custodian with respect to delivery of Deposited Securities and may charge the surrendering Owner a fee and
its expenses for doing so. 

  
 A-2 

	3.	REGISTRATION OF TRANSFER OF AMERICAN DEPOSITARY SHARES; COMBINATION AND SPLIT-UP OF RECEIPTS; INTERCHANGE OF CERTIFICATED AND UNCERTIFICATED AMERICAN DEPOSITARY SHARES. 

The Depositary, subject to the terms and conditions of the Deposit Agreement, shall register a transfer of American Depositary Shares on its
transfer books upon (i) in the case of certificated American Depositary Shares, surrender of the Receipt evidencing those American Depositary Shares, by the Owner or by a duly authorized attorney, properly endorsed or accompanied by proper
instruments of transfer or (ii) in the case of uncertificated American Depositary Shares, receipt from the Owner of a proper instruction (including, for the avoidance of doubt, instructions through DRS and Profile as provided in
Section 2.10 of that Agreement), and, in either case, duly stamped as may be required by the laws of the State of New York and of the United States of America. Upon registration of a transfer, the Depositary shall deliver the transferred
American Depositary Shares to or upon the order of the person entitled thereto. 
 The Depositary, subject to the terms and conditions of
the Deposit Agreement, shall upon surrender of a Receipt or Receipts for the purpose of effecting a split-up or combination of such Receipt or Receipts, execute and deliver a new Receipt or Receipts for any authorized number of American Depositary
Shares requested, evidencing the same aggregate number of American Depositary Shares as the Receipt or Receipts surrendered. 
 The
Depositary, upon surrender of certificated American Depositary Shares for the purpose of exchanging for uncertificated American Depositary Shares, shall cancel the Receipt evidencing those certificated American Depositary Shares and send the Owner a
statement confirming that the Owner is the owner of the same number of uncertificated American Depositary Shares. The Depositary, upon receipt of a proper instruction (including, for the avoidance of doubt, instructions through DRS and Profile as
provided in Section 2.10 of the Deposit Agreement) from the Owner of uncertificated American Depositary Shares for the purpose of exchanging for certificated American Depositary Shares, shall cancel those uncertificated American Depositary
Shares and register and deliver to the Owner a Receipt evidencing the same number of certificated American Depositary Shares. 
 As a
condition precedent to the delivery, registration of transfer, or surrender of any American Depositary Shares or split-up or combination of any Receipt or withdrawal of any Deposited Securities, the Depositary, the Custodian, or Registrar may
require payment from the depositor of the Shares or the presenter of the Receipt or instruction for registration of transfer or surrender of American Depositary Shares not evidenced by a Receipt of a sum sufficient to reimburse it for any tax or
other governmental charge and any stock transfer or registration fee with respect thereto (including any such tax or charge and fee with respect to Shares being deposited or withdrawn) and payment of any applicable fees as provided in the Deposit
Agreement, may require the production of 

  
 A-3 

 
proof satisfactory to it as to the identity and genuineness of any signature and may also require compliance with any regulations the Depositary may establish consistent with the provisions of
the Deposit Agreement. 
 The delivery of American Depositary Shares against deposit of Shares generally or against deposit of particular
Shares may be suspended, or the registration of transfer of American Depositary Shares in particular instances may be refused, or the registration of transfer of outstanding American Depositary Shares generally may be suspended, during any period
when the transfer books of the Depositary are closed, or if any such action is deemed necessary or advisable by the Depositary or the Company at any time or from time to time because of any requirement of law or of any government or governmental
body or commission, or under any provision of the Deposit Agreement, or for any other reason. Notwithstanding anything to the contrary in the Deposit Agreement or this Receipt, the surrender of outstanding American Depositary Shares and withdrawal
of Deposited Securities may not be suspended subject only to (i) temporary delays caused by closing the transfer books of the Depositary or the Company or the Foreign Registrar, if applicable, or the deposit of Shares in connection with voting
at a shareholders’ meeting, or the payment of dividends, (ii) the payment of fees, taxes and similar charges, and (iii) compliance with any U.S. or foreign laws or governmental regulations relating to the American Depositary Shares or
to the withdrawal of the Deposited Securities; in each case, the Depositary shall notify the Company as promptly as practicable of any such suspension or delay that is outside the ordinary course of business. 

The Depositary shall not knowingly accept for deposit under the Deposit Agreement any Shares that, at the time of deposit, are Restricted
Securities. 
  

	4.	LIABILITY OF OWNER FOR TAXES. 

 If any tax or other governmental charge shall become payable
with respect to or in connection with any American Depositary Shares or any Deposited Securities represented by any American Depositary Shares or in connection with a transaction to which Section 4.8 of the Deposit Agreement applies, that tax
or other governmental charge shall be payable by the Owner to the Company or the Depositary (for further payment to the Custodian if applicable). The Depositary may refuse to register any transfer of those American Depositary Shares or any
withdrawal of Deposited Securities represented by those American Depositary Shares until that payment is made, and may withhold any dividends or other distributions or the proceeds thereof, or may sell for the account of the Owner any part or all of
the Deposited Securities represented by those American Depositary Shares, and may apply those dividends or other distributions or the net proceeds of any sale of that kind in payment of that tax or other governmental charge but, even after a sale of
that kind, the Owner shall remain liable for any deficiency. The Depositary shall distribute any net proceeds of a sale made under Section 3.2 of the Deposit Agreement that are not used to pay taxes or governmental charges to the Owners
entitled to them in accordance with Section 4.1 of the Deposit Agreement. If the number 

  
 A-4 

 
of Shares represented by each American Depositary Share decreases as a result of a sale of Deposited Securities under Section 3.2 of the Deposit Agreement, the Depositary may call for
surrender of the American Depositary Shares to be exchanged on a mandatory basis for a lesser number of American Depositary Shares and may sell American Depositary Shares to the extent necessary to avoid distributing fractions of American Depositary
Shares in that exchange and distribute the net proceeds of that sale to the Owners entitled to them. 
 Every Holder and Owner agrees to
indemnify the Depositary, the Company, the Custodian, and any of their respective agents, directors, officers, employees and affiliates (as such term is defined in Regulation C under the Securities Act of 1933) for, and to hold each of them harmless
from, any claims by any governmental authority or any other entity or person with respect to taxes, additions to tax, penalties or interest arising out of any refund of taxes, reduced rate of withholding at source or other tax benefit obtained. The
obligations of Holders and Owners of American Depositary Shares under Section 3.2 of the Deposit Agreement shall survive any transfer of American Depositary Shares, any surrender of American Depositary Shares and withdrawal of Deposited
Securities, as well as the termination of the Deposit Agreement 
  

	5.	WARRANTIES ON DEPOSIT OF SHARES. 

 Every person depositing Shares under the Deposit Agreement
shall be deemed thereby to represent and warrant, that those Shares and each certificate therefor, if applicable, are validly issued, fully paid and nonassessable and were not issued in violation of any preemptive or similar rights of the holders of
outstanding securities of the Company and that the person making that deposit is duly authorized so to do. Every depositing person shall also be deemed to represent that the Shares, at the time of deposit, are not Restricted Securities. All
representations and warranties deemed made under Section 3.3 of the Deposit Agreement shall survive the deposit of Shares and delivery of American Depositary Shares. 
  

	6.	FILING PROOFS, CERTIFICATES, AND OTHER INFORMATION. 

 Any person presenting Shares for deposit
or any Owner or Holder may be required from time to time to file with the Depositary or the Custodian such proof of citizenship or residence, exchange control approval, or such information relating to the registration on the books of the Company or
the Foreign Registrar, if applicable, to execute such certificates and to make such representations and warranties, as the Depositary may deem necessary or proper. The Depositary may withhold the delivery or registration of transfer of any American
Depositary Shares, the distribution of any dividend or other distribution or of the proceeds thereof or the delivery of any Deposited Securities until that proof or other information is filed or those certificates are executed or those
representations and warranties are made. Each Holder and Owner agrees to comply with requests from the Company pursuant to applicable law and regulations, the rules and requirements of the Euronext Paris stock exchange, the Nasdaq Global Market and
of any 

  
 A-5 

 
other stock exchange on which the Shares or American Depositary Shares are, or may be, registered, traded or listed and any book-entry settlement system or
the articles of association or similar document of the Company, which are made to provide information, inter alia, as to the capacity in which such Holder or Owner owns American Depositary Shares (and Shares, as the case may be) and regarding the
identity of any other person(s) interested in such American Depositary Shares and the nature of such interest and various other matters, whether or not they are Holders or Owners at the time of such request. The Depositary agrees to use its
reasonable efforts to forward, upon the request of the Company and at the Company’s expense (unless otherwise agreed between the Company and the Depositary), any such request from the Company to the Owners and to forward to the Company any such
responses to such requests received by the Depositary, to the extent that disclosure is permitted under applicable law. 
 Holders and
Owners of American Depositary Shares may be required from time to time, and in a timely manner, to file such proof of taxpayer status, residence and beneficial ownership (as applicable), to execute such certificates and to make such representations
and warranties, or to provide any other information or documents, as the Company, the Depositary or the Custodian may deem necessary or proper to fulfill the Company’s, the Depositary’s or the Custodian’s obligations under applicable
law. 
 As conditions of accepting Shares for deposit, the Depositary may require (i) any certification required by the Depositary or
the Custodian in accordance with the provisions of the Deposit Agreement, (ii) a written order directing the Depositary to deliver to, or upon the written order of, the person or persons stated in that order, the number of American Depositary
Shares representing those Deposited Shares, (iii) evidence satisfactory to the Depositary that those Shares have been re-registered in the books of the Company or the Foreign Registrar in the name of the Depositary, a Custodian or a nominee of
the Depositary or a Custodian, (iv) evidence satisfactory to the Depositary that any necessary approval has been granted by any governmental body in each applicable jurisdiction and (v) an agreement or assignment, or other instrument
satisfactory to the Depositary, that provides for the prompt transfer to the Custodian of any dividend, or right to subscribe for additional Shares or to receive other property, that any person in whose name those Shares are or have been recorded
may thereafter receive upon or in respect of those Shares, or, in lieu thereof, such agreement of indemnity or other agreement as shall be satisfactory to the Depositary. 
  

	7.	CHARGES OF DEPOSITARY. 

 The following charges shall be incurred by any party depositing or
withdrawing Shares or by any party surrendering American Depositary Shares or to whom American Depositary Shares are issued (including, without limitation, issuance pursuant to a stock dividend or stock split declared by the Company or an exchange
of stock regarding the American Depositary Shares or Deposited Securities or a delivery of American Depositary Shares pursuant to Section 4.3 of the Deposit Agreement), or by Owners, as 

  
 A-6 

 
applicable: (1) taxes and other governmental charges, (2) such registration fees as may from time to time be in effect for the registration of transfers of Shares generally on the Share
register of the Company or Foreign Registrar and applicable to transfers of Shares to or from the name of the Depositary or its nominee or the Custodian or its nominee on the making of deposits or withdrawals hereunder, (3) such cable
(including SWIFT) and facsimile transmission fees and expenses as are expressly provided in the Deposit Agreement, (4) such expenses as are incurred by the Depositary in the conversion of foreign currency pursuant to Section 4.5 of the
Deposit Agreement, (5) a fee of $5.00 or less per 100 American Depositary Shares (or portion thereof) for the delivery of American Depositary Shares pursuant to Section 2.3, 4.3 or 4.4 of the Deposit Agreement and the surrender of American
Depositary Shares pursuant to Section 2.5 or 6.2 of the Deposit Agreement, (6) a fee of $.05 or less per American Depositary Share (or portion thereof) for any cash distribution made pursuant to the Deposit Agreement, including, but not
limited to Sections 4.1 through 4.4 and 4.8 of the Deposit Agreement, (7) a fee for the distribution of securities pursuant to Section 4.2 of the Deposit Agreement or of rights pursuant to Section 4.4 of that Agreement (where the
Depositary will not exercise or sell those rights on behalf of Owners), such fee being in an amount equal to the fee for the execution and delivery of American Depositary Shares referred to above which would have been charged as a result of the
deposit of such securities under the Deposit Agreement (for purposes of this item 7 treating all such securities as if they were Shares) but which securities are instead distributed by the Depositary to Owners, (8) in addition to any fee
charged under item 6, a fee of $.05 or less per American Depositary Share (or portion thereof) per annum for depositary services, which will be payable as provided in item 9 below, and (9) any other charges payable by the Depositary or the
Custodian, any of the Depositary’s or Custodian’s agents or the agents of the Depositary’s or Custodian’s agents, in connection with the servicing of Shares or other Deposited Securities (which charges shall be assessed against
Owners as of the date or dates set by the Depositary in accordance with Section 4.6 of the Deposit Agreement and shall be payable at the sole discretion of the Depositary by billing those Owners for those charges or by deducting those charges
from one or more cash dividends or other cash distributions). 
 The Depositary may collect any of its fees by deduction from any cash
distribution payable, or by selling a portion of any securities to be distributed, to Owners that are obligated to pay those fees. 
 In
performing its duties under this Deposit Agreement, the Depositary may use brokers, dealers, foreign currency dealers or other service providers that are owned by or affiliated with the Depositary and that may earn or share fees, spreads or
commissions. 
 The Depositary, subject to Article 8 hereof, may own and deal in any class of securities of the Company and its affiliates
and in American Depositary Shares. 
 From time to time, the Depositary may make payments to the Company to reimburse the Company for costs
and expenses generally arising out of establishment and maintenance of the American Depositary Shares program, waive fees and expenses for services provided by the Depositary or share revenue from the fees collected from Owners or Holders. In
performing its duties under the Deposit Agreement, the Depositary may use brokers, dealers or other service providers that are affiliates of the Depositary and that may earn or share fees and commissions. 

  
 A-7 

	8.	PRE-RELEASE OF RECEIPTS. 

 Notwithstanding Section 2.3 of the Deposit Agreement, and unless
otherwise instructed in writing by the Company, the Depositary may deliver American Depositary Shares prior to the receipt of Shares pursuant to Section 2.2 of the Deposit Agreement (a “Pre-Release”). The Depositary may,
pursuant to Section 2.5 of the Deposit Agreement, deliver Shares upon the surrender of American Depositary Shares that have been Pre-Released, whether or not that surrender is prior to the termination of that Pre-Release or the Depositary knows
that those American Depositary Shares have been Pre-Released. The Depositary may receive American Depositary Shares in lieu of Shares in satisfaction of a Pre-Release. Each Pre-Release must be (a) preceded or accompanied by a written
representation from the person to whom American Depositary Shares or Shares are to be delivered, that such person, or its customer, owns the Shares or American Depositary Shares to be remitted, as the case may be, (b) at all times fully
collateralized with cash or such other collateral as the Depositary deems appropriate, (c) terminable by the Depositary on not more than five (5) business days’ notice, and (d) subject to all indemnities and credit regulations
that the Depositary deems appropriate. The number of American Depositary Shares outstanding at any time as a result of Pre-Release will not normally exceed thirty percent (30%) of all American Depositary Shares outstanding; provided,
however, that the Depositary reserves the right to change or disregard that limit from time to time as it deems appropriate. 
 The
Depositary may retain for its own account any compensation received by it in connection with Pre-Release. 
  

	9.	TITLE TO AMERICAN DEPOSITARY SHARES. 

 It is a condition of the American Depositary Shares, and
every successive Owner and Holder of American Depositary Shares, by accepting or holding the same consents and agrees that American Depositary Shares evidenced by a Receipt, when the Receipt is properly endorsed or accompanied by proper instruments
of transfer, shall be transferable as certificated registered securities under the laws of the State of New York, and that American Depositary Shares not evidenced by Receipts shall be transferable as uncertificated registered securities under the
laws of the State of New York. The Depositary, notwithstanding any notice to the contrary, may treat the Owner of American Depositary Shares as the absolute owner thereof for the purpose of determining the person entitled to distribution of
dividends or other distributions or to any notice provided for in the Deposit Agreement and for all other purposes, and neither the Depositary nor the Company shall have any obligation or be subject to any liability under the Deposit Agreement to
any Holder of American Depositary Shares, but only to the Owner. 

  
 A-8 

	10.	VALIDITY OF RECEIPT. 

 This Receipt shall not be entitled to any benefits under the Deposit
Agreement or be valid or obligatory for any purpose, unless this Receipt shall have been (i) executed by the Depositary by the manual signature of a duly authorized officer of the Depositary or (ii) executed by the facsimile signature of a
duly authorized officer of the Depositary and countersigned by the manual signature of a duly authorized signatory of the Depositary or the Registrar or a co-registrar. 
  

	11.	REPORTS; INSPECTION OF TRANSFER BOOKS. 

 The Company is subject to the periodic reporting
requirements of the Securities Exchange Act of 1934 and, accordingly, files certain reports with the Securities and Exchange Commission. Those reports will be available for inspection and copying through the Commission’s EDGAR system or at
public reference facilities maintained by the Commission in Washington, D.C. 
 The Depositary will make available for inspection by Owners
at its Office any reports, notices and other communications, including any proxy soliciting material, received from the Company which are both (a) received by the Depositary as the holder of the Deposited Securities and (b) made generally
available to the holders of those Deposited Securities by the Company. The Company shall furnish reports and communications, including any proxy soliciting material to which Section 4.9 of the Deposit Agreement applies, to the Depositary in
English, to the extent such materials are required to be translated into English pursuant to any regulations of the Commission. 
 The
Depositary will keep books for the registration of American Depositary Shares and transfers of American Depositary Shares, which shall be open for inspection by the Owners at the Depositary’s Office during regular business hours,
provided that such inspection shall not be for the purpose of communicating with Owners in the interest of a business or object other than the business of the Company or a matter related to the Deposit Agreement or the American Depositary
Shares. 
  

	12.	DIVIDENDS AND DISTRIBUTIONS. 

 Whenever the Depositary receives any cash dividend or other cash
distribution on Deposited Securities, the Depositary will, if at the time of receipt thereof any amounts received in a foreign currency can in the judgment of the Depositary be converted on a reasonable basis into Dollars transferable to the United
States, and subject to the Deposit Agreement, convert that dividend or other cash distribution into Dollars and distribute the amount thus received (net of the fees and expenses of the Depositary as provided in Article 7 hereof and
Section 5.9 of the Deposit Agreement) to the Owners entitled thereto; provided, however, that if the Custodian or the Depositary is required to withhold and does withhold from that cash dividend or other cash distribution an
amount on account of taxes or other governmental charges, the amount distributed to the Owners of the American Depositary Shares representing those Deposited Securities shall be reduced accordingly. If a cash distribution would represent a return of
all or substantially 

  
 A-9 

 
all the value of the Deposited Securities underlying American Depositary Shares, the Depositary may require surrender of those American Depositary Shares and may require payment of or deduct the
fee for surrender of American Depositary Shares (whether or not it is also requiring surrender of American Depositary Shares) as a condition of making that cash distribution. A distribution of that kind shall be a Termination Option Event.

 Subject to the provisions of Section 4.11 and 5.9 of the Deposit Agreement, whenever the Depositary receives any distribution other
than a distribution described in Section 4.1, 4.3 or 4.4 of the Deposit Agreement on Deposited Securities (but not in exchange for or in conversion or in lieu of Deposited Securities), the Depositary will cause the securities or property
received by it to be distributed to the Owners entitled thereto, after deduction or upon payment of any fees and expenses of the Depositary and any taxes or other governmental charges, in any manner that the Depositary deems equitable and
practicable for accomplishing that distribution (which may be a distribution of depositary shares representing the securities received); provided, however, that if in the opinion of the Depositary such distribution cannot be made
proportionately among the Owners of Receipts entitled thereto, or if for any other reason the Depositary, after consultation with the Company to the extent practicable, deems such distribution not to be lawful and feasible, the Depositary may adopt
such other method as it may deem equitable and practicable for the purpose of effecting such distribution, including, but not limited to, the public or private sale of the securities or property thus received, or any part thereof, and distribution
of the net proceeds of any such sale (net of the fees and expenses of the Depositary as provided in Article 7 hereof and Section 5.9 of the Deposit Agreement) to the Owners entitled thereto all in the manner and subject to the conditions
set forth in Section 4.1 of the Deposit Agreement. The Depositary may withhold any distribution of securities under Section 4.2 of the Deposit Agreement if it has not received satisfactory assurances from the Company that the distribution
does not require registration under the Securities Act of 1933. The Depositary may sell, by public or private sale, an amount of securities or other property it would otherwise distribute under this Article that is sufficient to pay its fees and
expenses in respect of that distribution. If a distribution under Section 4.2 of the Deposit Agreement would represent a return of all of substantially all the value of the Deposited Securities underlying American Depositary Shares, the
Depositary may require surrender of those American Depositary Shares and may require payment of or deduct the fee for surrender of American Depositary Shares (whether or not it is also requiring surrender of American Depositary Shares) as a
condition of making that distribution. A distribution of that kind shall be a Termination Option Event. 
 Whenever the Depositary
receives any distribution consisting of a dividend in, or free distribution of, Shares, the Depositary may deliver to the Owners entitled thereto, an aggregate number of American Depositary Shares representing the amount of Shares received as that
dividend or free distribution, subject to the terms and conditions of the Deposit Agreement with respect to the deposit of Shares and after deduction or upon 

  
 A-10 

 
issuance of American Depositary Shares, including the withholding of any tax or other governmental charge as provided in Section 4.11 of the Deposit Agreement and the payment of the fees and
expenses of the Depositary as provided in Article 7 hereof and Section 5.9 of the Deposit Agreement (and the Depositary may sell, by public or private sale, an amount of Shares received (or American Depositary Shares representing those Shares)
sufficient to pay its fees and expenses in respect of that distribution). In lieu of delivering fractional American Depositary Shares, the Depositary may sell the amount of Shares represented by the aggregate of those fractions (or American
Depositary Shares representing those Shares) and distribute the net proceeds, all in the manner and subject to the conditions described in Section 4.1 of the Deposit Agreement. If and to the extent that additional American Depositary Shares are
not so delivered and Shares or American Depositary Shares are not sold, each American Depositary Share shall thenceforth also represent the additional Shares distributed on the Deposited Securities represented thereby. 

If the Company declares a distribution in which holders of Deposited Securities have a right to elect whether to receive cash, Shares or other
securities or a combination of those things, or a right to elect to have a distribution sold on their behalf, the Depositary may, after consultation with the Company, make that right of election available for exercise by Owners any manner the
Depositary considers to be lawful and practical. As a condition of making a distribution election right available to Owners, the Depositary may require satisfactory assurances from the Company that doing so does not require registration of any
securities under the Securities Act of 1933. 
 In the event that the Depositary determines that any distribution received or to be made by
the Depositary (including Shares and rights to subscribe therefor) is subject to any tax or other governmental charge that the Depositary is obligated to withhold, the Depositary may sell, by public or private sale, all or a portion of the
distributed property (including Shares and rights to subscribe therefor) in the amounts and manner the Depositary deems necessary and practicable to pay any those taxes or charges, and the Depositary shall distribute the net proceeds of that sale,
after deduction of those taxes or charges, to the Owners entitled thereto in proportion to the number of American Depositary Shares held by them respectively. 

None of the Company, the Depositary or the Custodian shall be liable for the failure by any Holder or Owner to obtain the benefits of credits
on the basis of any tax withheld or paid against such Holder’s or Owner’s tax liability. 
  

	13.	RIGHTS. 

 (a) If rights are granted to the Depositary in respect of deposited Shares to purchase
additional Shares or other securities, the Company and the Depositary shall endeavor to consult as to the actions, if any, the Depositary should take in connection with that grant of rights. The Depositary may, to the extent deemed by it to be
lawful and practical (i) if requested in writing by the Company, grant to all or certain Owners rights 

  
 A-11 

 
to instruct the Depositary to purchase the securities to which the rights relate and deliver those securities or American Depositary Shares representing those securities to Owners, (ii) if
requested in writing by the Company, deliver the rights to or to the order of certain Owners, or (iii) sell the rights to the extent practicable and distribute the net proceeds of that sale to Owners entitled to those proceeds. To the extent
rights are not exercised, delivered or disposed of under (i), (ii) or (iii) above, the Depositary shall permit the rights to lapse unexercised. 

(b) If the Depositary will act under (a)(i) above, the Company and the Depositary will enter into a separate agreement setting forth the
conditions and procedures applicable to the particular offering. Upon instruction from an applicable Owner in the form the Depositary specified and upon payment by that Owner to the Depositary of an amount equal to the purchase price of the
securities to be received upon the exercise of the rights, the Depositary shall, on behalf of that Owner, exercise the rights and purchase the securities. The purchased securities shall be delivered to, or as instructed by, the Depositary. The
Depositary shall (i) deposit the purchased Shares under the Deposit Agreement and deliver American Depositary Shares representing those Shares to that Owner or (ii) deliver or cause the purchased Shares or other securities to be delivered
to or to the order of that Owner. The Depositary will not act under (a)(i) above unless the offer and sale of the securities to which the rights relate are registered under the Securities Act of 1933 or the Depositary has received an opinion of
United States counsel that is satisfactory to it to the effect that those securities may be sold and delivered to the applicable Owners without registration under the Securities Act of 1933. 

(c) If the Depositary will act under (a)(ii) above, the Company and the Depositary will enter into a separate agreement setting forth the
conditions and procedures applicable to the particular offering. Upon (i) the request of an applicable Owner to deliver the rights allocable to the American Depositary Shares of that Owner to an account specified by that Owner to which the
rights can be delivered and (ii) receipt of such documents as the Company and the Depositary agreed to require to comply with applicable law, the Depositary will deliver those rights as requested by that Owner. 

(d) If the Depositary will act under (a)(iii) above, the Depositary will use reasonable efforts to sell the rights in proportion to the number
of American Depositary Shares held by the applicable Owners and pay the net proceeds to the Owners otherwise entitled to the rights that were sold, upon an averaged or other practical basis without regard to any distinctions among such Owners
because of exchange restrictions or the date of delivery of any American Depositary Shares or otherwise. 
 (e) Payment or deduction of the
fee of the Depositary as provided in Section 5.9 of the Deposit Agreement and payment or deduction of the expenses of the Depositary and any applicable taxes or other governmental charges shall be conditions of any delivery of securities or
payment of cash proceeds under Section 4.4 of that Agreement. 

  
 A-12 

 (f) The Depositary shall not be responsible for any failure to determine that it may be lawful or
feasible to make rights available to or exercise rights on behalf of Owners in general or any Owner in particular , or to sell rights. 
  

	14.	CONVERSION OF FOREIGN CURRENCY. 

 Whenever the Depositary or the Custodian receives foreign
currency, by way of dividends or other distributions or the net proceeds from the sale of securities, property or rights, and if at the time of the receipt thereof the foreign currency so received can in the judgment of the Depositary be converted
on a reasonable basis into Dollars and the resulting Dollars transferred to the United States, the Depositary shall convert or cause to be converted by sale or in any other manner that it may determine that foreign currency into Dollars, and
those Dollars shall be distributed to the Owners entitled thereto. A cash distribution may be made upon an averaged or other practicable basis without regard to any distinctions among Owners based on exchange restrictions, the date of delivery of
any American Depositary Shares or otherwise and shall be net of any expenses of conversion into Dollars incurred by the Depositary as provided in Section 5.9 of the Deposit Agreement. 

If a conversion of foreign currency or the repatriation or distribution of Dollars can be effected only with the approval or license of any
government or agency thereof, the Depositary may, but will not be required to, file an application for that approval or license. 
 If the
Depositary, after consultation with the Company to the extent practicable, determines that in its judgment any foreign currency received by the Depositary or the Custodian is not convertible on a reasonable basis into Dollars transferable to the
United States, or if any approval or license of any government or agency thereof that is required for such conversion is not filed or sought by the Depositary, or if any required approval or license is not obtained within a reasonable period as
determined by the Depositary, the Depositary may distribute the foreign currency received by the Depositary to, or in its discretion may hold such foreign currency uninvested and without liability for interest thereon for the respective accounts of,
the Owners entitled to receive the same. 
 If any conversion of foreign currency, in whole or in part, cannot be effected for distribution
to some of the Owners entitled thereto, the Depositary may in its discretion make that conversion and distribution in Dollars to the extent practicable and permissible to the Owners entitled thereto and may distribute the balance of the foreign
currency received by the Depositary to, or hold that balance uninvested and without liability for interest thereon for the account of, the Owners entitled thereto. 

The Depositary may convert currency itself or through any of its affiliates and, in those cases, acts as principal for its own account and not
as agent, advisor, broker or fiduciary on behalf of any other person and earns revenue, including, without limitation, transaction spreads, that it will retain for its own account. The revenue is based on, among other things, the difference between
the 

  
 A-13 

 
exchange rate assigned to the currency conversion made under this Deposit Agreement and the rate that the Depositary or its affiliate receives when buying or selling foreign currency for its own
account. The Depositary makes no representation that the exchange rate used or obtained in any currency conversion under this Deposit Agreement will be the most favorable rate that could be obtained at the time or that the method by which that rate
will be determined will be the most favorable to Owners, subject to the Depositary’s obligations under Section 5.3. The methodology used to determine exchange rates used in currency conversions is available upon request. 

 

	15.	RECORD DATES. 

 Whenever a cash dividend, cash distribution or any other distribution is made on
Deposited Securities or rights to purchase Shares or other securities are issued with respect to Deposited Securities (which rights will delivered to or exercised or sold on behalf of Owners in accordance with Section 4.4 of the Deposit
Agreement) or the Depositary receives notice that a distribution or issuance of that kind will be made, or whenever the Depositary receives notice that a meeting of holders of Shares will be held in respect of which the Company has requested the
Depositary to send a notice under Section 4.7 of the Deposit Agreement, or whenever the Depositary will assess a fee or charge against the Owners, or whenever for any reason the Depositary causes a change in the number of Shares that are
represented by each American Depositary Share, or whenever the Depositary otherwise finds it necessary or convenient, the Depositary shall fix a record date, which shall be the same as, or as near as practicable to, any corresponding record date set
by the Company with respect to Shares, (a) for the determination of the Owners (i) who shall be entitled to receive the benefit of that dividend or other distribution or those rights, (ii) who shall be entitled to give instructions
for the exercise of voting rights at that meeting, (iii) who shall be responsible for that fee or charge or (iv) for any other purpose for which the record date was set, or (b) on or after which each American Depositary Share will
represent the changed number of Shares. Subject to the provisions of Sections 4.1 through 4.5 of the Deposit Agreement and to the other terms and conditions of the Deposit Agreement, the Owners on a record date fixed by the Depositary shall be
entitled to receive the amount distributable by the Depositary with respect to that dividend or other distribution or those rights or the net proceeds of sale thereof in proportion to the number of American Depositary Shares held by them
respectively, to give voting instructions or to act in respect of the other matter for which that record date was fixed, or be responsible for that fee or charge, as the case may be. 

 

	16.	VOTING OF DEPOSITED SHARES. 

 (a) Upon receipt of notice of any meeting of holders of Shares at
which holders of Shares will be entitled to vote, if requested in writing by the Company, the Depositary shall, as soon as practicable thereafter, Disseminate to the Owners a notice, the form of which shall be in the sole discretion of the
Depositary, that shall contain (a) the information contained in the notice of meeting received by the Depositary from the Company, (b) a statement that the Owners as of the close of business on a specified record date will be entitled,
subject to any applicable provision of French law and of the 

  
 A-14 

 
articles of association or similar documents of the Company, to instruct the Depositary as to the exercise of the voting rights pertaining to the number of Shares represented by their respective
American Depositary Shares, (c) a statement as to the manner in which those instructions may be given and (d) the last date on which the Depositary will accept instructions (the “Instruction Cutoff Date”). 

(b) Upon the written request of an Owner of American Depositary Shares, as of the date of the request or, if a record date was specified by
the Depositary, as of that record date, received on or before any Instruction Cutoff Date established by the Depositary, the Depositary may, and if the Depositary sent a notice under the preceding paragraph shall, endeavor, in so far
as practicable, to vote or cause to be voted the amount of deposited Shares represented by those American Depositary Shares in accordance with the instructions set forth in that request. The Depositary shall not vote or attempt to exercise the right
to vote that attaches to the deposited Securities other than in accordance with instructions given by Owners and received by the Depositary. 

(c) There can be no assurance that Owners generally or any Owner in particular will receive the notice described in paragraph
(a) above in time to enable Owners to give instructions to the Depositary prior to the Instruction Cutoff Date. 
 (d) In
order to give Owners a reasonable opportunity to instruct the Depositary as to the exercise of voting rights relating to Shares, if the Company will request the Depositary to Disseminate a notice under paragraph (a) above, the Company
shall give the Depositary notice of the meeting, details concerning the matters to be voted upon and copies of materials to be made available to holders of Shares in connection with the meeting not less than 30 days prior to the meeting date, in
which case the Depositary shall upon receipt of the request use its commercially reasonable efforts to distribute to Owners the material described in the first paragraph of Section 4.7 of the Deposit Agreement and carry out the further actions
set forth in Section 4.7 of the Deposit Agreement. 
 Notwithstanding anything in Section 4.7 of the Deposit Agreement to the
contrary, the Depositary and the Company may modify, amend or adopt additional procedures from time to time as they determine may be necessary or appropriate. 

Without prejudice to the Depositary’s rights under Section 2.9, the Depositary will take no action to impair the ability of the
Custodian to vote the number of Shares (including the Shares held by the Depositary in registered form) necessary to carry out the instructions of all Owners under this Section 4.7. 

 

	17.	TENDER AND EXCHANGE OFFERS; REDEMPTION, REPLACEMENT OR CANCELLATION OF DEPOSITED SECURITIES. 

(a) The Depositary shall not tender any Deposited Securities in response to any voluntary cash tender offer, exchange offer or similar offer
made to holders of 

  
 A-15 

 
Deposited Securities (a “Voluntary Offer”) except (i) when instructed in writing to do so by an Owner surrendering American Depositary Shares and subject to any conditions
or procedures the Depositary may require. 
 (b) If the Depositary receives a written notice that Deposited Securities have been redeemed
for cash or otherwise purchased for cash in a transaction that is mandatory and binding on the Depositary as a holder of those Deposited Securities (a “Redemption”), the Depositary, at the expense of the Company (unless otherwise
agreed between the Company and the Depositary), shall (i) if required, surrender Deposited Securities that have been redeemed to the issuer of those securities or its agent on the redemption date, (ii) Disseminate a notice to Owners
(A) notifying them of that Redemption, (B) calling for surrender of a corresponding number of American Depositary Shares and (C) notifying them that the called American Depositary Shares have been converted into a right only to
receive the money received by the Depositary upon that Redemption and those net proceeds shall be the Deposited Securities to which Owners of those converted American Depositary Shares shall be entitled upon surrenders of those American Depositary
Shares in accordance with Section 2.5 or 6.2 of the Deposit Agreement and (iii) distribute the money received upon that Redemption to the Owners entitled to it upon surrender by them of called American Depositary Shares in accordance with
Section 2.5 of that Agreement (and, for the avoidance of doubt, Owners shall not be entitled to receive that money or other property under Section 4.1 or 4.2 of that Agreement). If the Redemption affects less than all the Deposited
Securities, the Depositary shall call for surrender a corresponding portion of the outstanding American Depositary Shares and only those American Depositary Shares will automatically be converted into a right to receive the net proceeds of the
Redemption. The Depositary shall allocate the American Depositary Shares converted under the preceding sentence among the Owners pro-rata to their respective holdings of American Depositary Shares immediately prior to the Redemption, except
that the allocations may be adjusted so that no fraction of a converted American Depositary Share is allocated to any Owner. A Redemption of all or substantially all of the Deposited Securities shall be a Termination Option Event. 

(c) If the Depositary is notified of or there occurs any change in nominal value or any subdivision, combination or any other reclassification
of the Deposited Securities or any recapitalization, reorganization, sale of assets substantially as an entirety, merger or consolidation affecting the issuer of the Deposited Securities or to which it is a party that is mandatory and binding on the
Depositary as a holder of Deposited Securities and as a result securities or other property have been or will be delivered in exchange, conversion, replacement or in lieu of, Deposited Securities (a “Replacement”), then the
Depositary shall, if required, surrender the old Deposited Securities affected by that Replacement of Shares and hold, as new Deposited Securities under the Deposit Agreement, the new securities or other property delivered to it in that Replacement.
However, the Depositary may elect to sell those new Deposited Securities if in the opinion of the Depositary, after consultation with the Company or its successor 

  
 A-16 

 
entity to the extent practicable, it is not lawful or not practical for it to hold those new Deposited Securities under the Deposit Agreement because those new Deposited Securities may not be
distributed to Owners without registration under the Securities Act of 1933 or for any other reason, at public or private sale, at such places and on such terms as it deems proper and proceed as if those new Deposited Securities had been Redeemed
under paragraph (b) above. A Replacement shall be a Termination Option Event. 
 (d) In the case of a Replacement where the new
Deposited Securities will continue to be held under the Deposit Agreement, the Depositary may call for the surrender of outstanding Receipts to be exchanged for new Receipts specifically describing the new Deposited Securities and the number of
those new Deposited Securities represented by each American Depositary Share. If the number of Shares represented by each American Depositary Share decreases as a result of a Replacement, the Depositary may, after consultation with the Company to
the extent practicable, call for surrender of the American Depositary Shares to be exchanged on a mandatory basis for a lesser number of American Depositary and may sell American Depositary Shares to the extent necessary to avoid distributing
fractions of American Depositary Shares in that exchange and distribute the net proceeds of that sale to the Owners entitled to them. 
 (e)
If there are no Deposited Securities with respect to American Depositary Shares, including if the Deposited Securities are cancelled, or the Deposited Securities with respect to American Depositary Shares become apparently worthless, the Depositary
may call for surrender of those American Depositary Shares or may cancel those American Depositary Shares, upon notice to Owners, and a Termination Option Event occurs. 

 

	18.	LIABILITY OF THE COMPANY AND DEPOSITARY. 

 Neither the Depositary nor the Company nor any of
their respective directors, employees, agents or affiliates shall incur any liability to any Owner or Holder, (i) if by reason of any provision of any present or future law or regulation of the United States or any other country, or of any
governmental or regulatory authority, or by reason of any provision, present or future, of the articles of association or any similar document of the Company, or by reason of any provision of any securities issued or distributed by the Company, or
any offering or distribution thereof, or by reason of any act of God or war or terrorism or other circumstances beyond its control, the Depositary or the Company is prevented from, forbidden to or delayed in, or could be subject to any civil or
criminal penalty on account of doing or performing and therefore does not do or perform, any act or thing that, by the terms of the Deposit Agreement or Deposited Securities, it is provided shall be done or performed, (ii) by reason of any
exercise of, or failure to exercise, any discretion provided for in the Deposit Agreement (including any determination by the Depositary to take, or not take, any action that the Deposit Agreement provides the Depositary may take), (iii) for
the inability of any Owner or Holder to benefit from any distribution, offering, right or other benefit that is made 

  
 A-17 

 
available to holders of Deposited Securities but is not, under the terms of the Deposit Agreement, made available to Owners or Holders, or (iv) for any special, consequential, indirect or
punitive damages for any breach of the terms of the Deposit Agreement. Where, by the terms of a distribution to which Section 4.1, 4.2 or 4.3 of the Deposit Agreement applies, or an offering to which Section 4.4 of the Deposit Agreement
applies, that distribution or offering may not be made available to Owners of Receipts, and the Depositary may not dispose of that distribution or offering on behalf of such Owners and make the net proceeds available to Owners, then the Depositary
shall not make that distribution or offering available to Owners, and shall allow any rights, if applicable, to lapse. 
 Neither the
Company nor the Depositary assumes any obligation or shall be subject to any liability under the Deposit Agreement to Owners or Holders, except that they agree to perform their obligations specifically set forth in the Deposit Agreement without
negligence or bad faith. The Depositary shall not be subject to any liability with respect to the validity or worth of the Deposited Securities. Neither the Depositary nor the Company shall be under any obligation to appear in, prosecute or defend
any action, suit, or other proceeding in respect of any Deposited Securities or in respect of the American Depositary Shares, on behalf of any Owner or Holder or other person. Each of the Depositary and the Company may rely, and shall be protected
in relying upon, any written notice, request, direction or other document believed by it to be genuine and to have been signed or presented by the proper party or parties. Neither the Depositary nor the Company, nor any of their respective
affiliates (as such term is defined in Regulation C under the Securities Act of 1933) or agents, shall be liable for any action or non-action by it in reliance upon the advice of or information from legal counsel, accountants, any person presenting
Shares for deposit, any Owner or Holder, or any other person believed by it in good faith to be competent to give such advice or information. The Depositary shall not be liable for any acts or omissions made by a successor depositary whether in
connection with a previous act or omission of the Depositary or in connection with a matter arising wholly after the removal or resignation of the Depositary, provided that in connection with the issue out of which such potential liability arises,
the Depositary performed its obligations without negligence or bad faith while it acted as Depositary. The Depositary shall not be liable for the acts or omissions of any securities depository, clearing agency or settlement system in connection with
or arising out of book-entry settlement of American Depositary Shares or Deposited Securities or otherwise. In the absence of bad faith on its part, the Depositary shall not be responsible for any failure to carry out any instructions to vote any of
the Deposited Securities or for the manner in which any such vote is cast or the effect of any such vote. Each of the Depositary and the Company may rely, and shall be protected in acting upon, any written notice, request, direction or other
document believed by it to be genuine and to have been signed or presented by the proper party or parties. Neither the Company nor the Depositary shall have any duty to make any determination or provide any information as to the tax status of the
Company or any liability for any tax consequences that may be incurred by Owners or Holders as a result of owning or holding American Depositary Shares, 

  
 A-18 

 
including without limitation, tax consequences resulting from the Company (or any of its subsidiaries) being treated as a “Passive Foreign Investment Company” (“PFIC”) (in
each case as defined in the U.S. Internal Revenue Code and the regulations issued thereunder) or otherwise. The Company may have been in the past and may be in the future a PFIC for U.S. Federal income tax purposes. Owners must consult their own tax
advisers as to the potential application of the PFIC rules. No disclaimer of liability under the Securities Act of 1933 is intended by any provision of the Deposit Agreement. 
  

	19.	RESIGNATION AND REMOVAL OF THE DEPOSITARY; APPOINTMENT OF SUCCESSOR CUSTODIAN. 

 The Depositary
may at any time resign as Depositary under the Deposit Agreement by written notice of its election so to do delivered to the Company, to become effective upon the appointment of a successor depositary and its acceptance of such appointment as
provided in the Deposit Agreement. The Depositary may at any time be removed by the Company by 120 days’ prior written notice of that removal, to become effective upon the later of (i) the 120th day after delivery of the notice to the
Depositary and (ii) the appointment of a successor depositary and its acceptance of its appointment as provided in the Deposit Agreement. The Depositary in its discretion may at any time appoint a substitute or additional custodian or
custodians. 
  

	20.	AMENDMENT. 

 The form of the Receipts and any provisions of the Deposit Agreement may at any
time and from time to time be amended by agreement between the Company and the Depositary without the consent of Owners or Holders in any respect which they may deem necessary or desirable. Any amendment that would shall impose or increase any fees
or charges (other than taxes and other governmental charges, registration fees, cable, telex or facsimile transmission costs, delivery costs or other such expenses), or that would otherwise prejudice any substantial existing right of Owners, shall,
however, not become effective as to outstanding American Depositary Shares until the expiration of 30 days after notice of that amendment has been Disseminated to the Owners of outstanding American Depositary Shares. Every Owner and Holder, at the
time any amendment so becomes effective, shall be deemed, by continuing to hold American Depositary Shares or any interest therein, to consent and agree to that amendment and to be bound by the Deposit Agreement as amended thereby. Upon the
effectiveness of an amendment to the form of Receipt, including a change in the number of Shares represented by each American Depositary Share, the Depositary may call for surrender of Receipts to be replaced with new Receipts in the amended form or
call for surrender of American Depositary Shares to effect that change of ratio. In no event shall any amendment impair the right of the Owner to surrender American Depositary Shares and receive delivery of the Deposited Securities represented
thereby, except in order to comply with mandatory provisions of applicable law. 

  
 A-19 

	21.	TERMINATION OF DEPOSIT AGREEMENT. 

 (a) The Company may terminate the Deposit Agreement by
notice to the Depositary. The Depositary may terminate this Deposit Agreement if (i) at any time 60 days shall have expired after the Depositary delivered to the Company a written resignation notice and a successor depositary has not been
appointed and accepted its appointment as provided in Section 5.4 of that Agreement, (ii) an Insolvency Event or Delisting Event occurs with respect to the Company or (iii) a Termination Option Event has occurred or will occur. If a
termination of the Deposit Agreement has been initiated by the Company or the Depositary, the Depositary shall Disseminate a notice of termination to the Owners of all American Depositary Shares then outstanding setting a date for termination (the
“Termination Date”), which shall be at least 90 days after the date of that notice, and the Deposit Agreement shall terminate on that Termination Date. 

(b) After the Termination Date, the Company shall be discharged from all obligations under the Deposit Agreement except for its obligations to
the Depositary under Sections 5.8 and 5.9 of that Agreement. 
 (c) At any time after the Termination Date, the Depositary may sell the
Deposited Securities then held under the Deposit Agreement and may thereafter hold uninvested the net proceeds of any such sale, together with any other cash then held by it hereunder, unsegregated and without liability for interest, for the pro
rata benefit of the Owners of American Depositary Shares that remain outstanding, and those Owners will become general creditors of the Depositary with respect to those net proceeds. After making that sale, the Depositary shall be discharged from
all obligations under the Deposit Agreement, except (i) to account for the net proceeds and other cash (after deducting, in each case, the fee of the Depositary for the surrender of American Depositary Shares, any expenses for the account of
the Owner of such American Depositary Shares in accordance with the terms and conditions of the Deposit Agreement and any applicable taxes or governmental charges) and (ii) for its obligations under Section 5.8 of that Agreement and
(iii) to act as provided in the paragraph (d) below. 
 (d) After the Termination Date, the Depositary shall continue to receive
dividends and other distributions pertaining to Deposited Securities (that have not been sold), may sell rights and other property as provided in the Deposit Agreement and shall deliver Deposited Securities (or sale proceeds) upon surrender of
American Depositary Shares (after payment or upon deduction, in each case, of the fee of the Depositary for the surrender of American Depositary Shares, any expenses for the account of the Owner of those American Depositary Shares in accordance with
the terms and conditions of the Deposit Agreement and any applicable taxes or governmental charges). However, after the Termination Date, (i) the Depositary may refuse to accept surrenders of American Depositary Shares for the purpose of
withdrawal of Deposited Securities (that have not been sold) if in its judgment the requested withdrawal would interfere with its efforts to sell the Deposited Securities, (ii) the Depositary will not be required to deliver cash proceeds of the
sale of Deposited Securities until all Deposited Securities have been sold and (iii) the Depositary may discontinue the registration of transfers of American 

  
 A-20 

 
Depositary Shares and suspend the distribution of dividends and other distributions on Deposited Securities to the Owners and need not give any further notices or perform any further acts under
the Deposit Agreement except as provided in Section 6.2 of that Agreement. 
  

	22.	DTC DIRECT REGISTRATION SYSTEM AND PROFILE MODIFICATION SYSTEM. 

 (a) Notwithstanding the
provisions of Section 2.4 of the Deposit Agreement, the parties acknowledge that DTC’s Direct Registration System (“DRS”) and Profile Modification System (“Profile”) apply to the American Depositary Shares
upon acceptance thereof to DRS by DTC. DRS is the system administered by DTC that facilitates interchange between registered holding of uncertificated securities and holding of security entitlements in those securities through DTC and a DTC
participant. Profile is a required feature of DRS that allows a DTC participant, claiming to act on behalf of an Owner of American Depositary Shares, to direct the Depositary to register a transfer of those American Depositary Shares to DTC or its
nominee and to deliver those American Depositary Shares to the DTC account of that DTC participant without receipt by the Depositary of prior authorization from the Owner to register that transfer. 

(b) In connection with DRS/Profile, the parties acknowledge that the Depositary will not determine whether the DTC participant that is
claiming to be acting on behalf of an Owner in requesting registration of transfer and delivery described in paragraph (a) above has the actual authority to act on behalf of that Owner (notwithstanding any requirements under the Uniform
Commercial Code). For the avoidance of doubt, the provisions of Sections 5.3 and 5.8 of the Deposit Agreement apply to the matters arising from the use of the DRS/Profile. The parties agree that the Depositary’s reliance on and compliance with
instructions received by the Depositary through the DRS/Profile system and otherwise in accordance with the Deposit Agreement, shall not constitute negligence or bad faith on the part of the Depositary. 

 

	23.	APPOINTMENT OF AGENT FOR SERVICE OF PROCESS; SUBMISSION TO JURISDICTION; JURY TRIAL WAIVER; WAIVER OF IMMUNITIES. 

The Company has (i) appointed CorpoMax, Inc., 2915 Ogletown Road, Newark, DE 19713, as the Company’s U.S. registered agent upon which
process may be served in any suit or proceeding arising out of or relating to the Shares or Deposited Securities, the American Depositary Shares, the Receipts or this Agreement, (ii) consented and submitted to the jurisdiction of any state or
federal court in the State of New York in which any such suit or proceeding may be instituted, and (iii) agreed that service of process upon said U.S. registered agent shall be deemed in every respect effective service of process upon the
Company in any such suit or proceeding. 
 EACH PARTY TO THE DEPOSIT AGREEMENT (INCLUDING, FOR AVOIDANCE OF DOUBT, EACH OWNER AND HOLDER)
THEREBY 

  
 A-21 

 
IRREVOCABLY WAIVES, TO THE FULLEST EXTENT PERMITTED BY APPLICABLE LAW, ANY RIGHT IT MAY HAVE TO A TRIAL BY JURY IN ANY SUIT, ACTION OR PROCEEDING AGAINST THE COMPANY AND/OR THE DEPOSITARY
DIRECTLY OR INDIRECTLY ARISING OUT OF OR RELATING TO THE SHARES OR OTHER DEPOSITED SECURITIES, THE AMERICAN DEPOSITARY SHARES OR THE RECEIPTS, THE DEPOSIT AGREEMENT OR ANY TRANSACTION CONTEMPLATED HEREIN OR THEREIN, OR THE BREACH HEREOF OR THEREOF,
INCLUDING WITHOUT LIMITATION ANY QUESTION REGARDING EXISTENCE, VALIDITY OR TERMINATION (WHETHER BASED ON CONTRACT, TORT OR ANY OTHER THEORY). 

To the extent that the Company or any of its properties, assets or revenues may have or hereafter become entitled to, or have attributed to
it, any right of immunity, on the grounds of sovereignty or otherwise, from any legal action, suit or proceeding, from the giving of any relief in any respect thereof, from setoff or counterclaim, from the jurisdiction of any court, from service of
process, from attachment upon or prior to judgment, from attachment in aid of execution or judgment, or other legal process or proceeding for the giving of any relief or for the enforcement of any judgment, in any jurisdiction in which proceedings
may at any time be commenced, with respect to its obligations, liabilities or any other matter under or arising out of or in connection with the Shares or Deposited Securities, the American Depositary Shares, the Receipts or the Deposit Agreement,
the Company, to the fullest extent permitted by law, hereby irrevocably and unconditionally waives, and agrees not to plead or claim, any such immunity and consents to such relief and enforcement. 

 

	24.	DISCLOSURE OF INTERESTS. 

 In order to comply with applicable laws and regulations or the
articles of association or similar document of the Company, the Company may from time to time request each Owner and Holder to provide to the Depositary information relating to: (a) the capacity in which it holds American
Depositary Shares, (b) the identity of any Holders or other persons or entities then or previously interested in those American Depositary Shares and the nature of those interests and (c) any other matter where disclosure of
such matter is required for that compliance. Each Owner and Holder agrees to provide all information known to it in response to a request made pursuant to this Section. Each Holder consents to the disclosure by the Owner or other
Holder through which it holds American Depositary Shares, directly or indirectly, of all information responsive to a request made pursuant to this Section relating to that Holder that is known to that Owner or other Holder. The Depositary
agrees to use reasonable efforts, at the Company’s expense (unless otherwise agreed between the Company and the Depositary), to comply with written instructions requesting that the Depositary forward any request authorized under this
Section to the Owners and to forward to the Company any responses it receives in response to that request. 

  
 A-22 

 Each Owner and Holder of American Depositary Shares further agrees to comply with the laws and
regulations of the United States and the Republic of France (if and to the extent applicable) with respect to the disclosure requirements regarding beneficial ownership of Shares, all as if the American Depositary Shares were the Shares
represented thereby, which is deemed to include, inter alia, requirements to make notifications and filings within the required timeframes to the Company, to the Commision, to the French Autorité des Marchés Financiers and any other
authorities in the United States or in the Republic of France. The Company reserves the right to instruct Holders to deliver their American Depositary Shares for cancellation and withdrawal of the Deposited Securities so as to permit the Company to
deal directly with the Holder thereof as a holder of Shares and Holders agree to comply with such instructions. The Depositary agrees to cooperate with the Company in its efforts to inform Holders of the Company’s exercise of its rights under
this paragraph and agrees to consult with, and provide reasonable assistance without risk, liability or expense on the part of the Depositary, to the Company on the manner or manners in which it may enforce such rights with respect to any Holder.

  
 A-23EX-10.1

 Exhibit 10.1 
  

 
 (premises leased for exclusive use of offices – offices-laboratories) 

PFO2 
 Real Estate Investment Trust (REIT) which has its
registered office in PARIS 17th – 9 rue Jadin, registered in the Trade and Companies Register of Paris under no. D 513 811 638, 

represented by PERIAL Asset Management, Sole Proprietor Simplified Joint Stock Company (SASU) with share capital of €495,840, which has its registered
office in PARIS 17th – 9 Rue Jadin, registered in the Trade Register of PARIS, under number 775 696 446, Management Company of the “PFO2” company, under the bylaws filed with
Mr. DECHIN, Notary in PARIS, on July 23, 2009. 
 The said PERIAL Asset Management company represented by its CEO, Mr. Jean-Christophe
ANTOINE; 
 Hereinafter referred to as “The Lessor” 

AND, 
 The ERYTECH PHARMA company, with share capital of
€ 688,276.10 which has its registered office in LYON 69008, 60 avenue Rockefeller – ADENINE Building, registered in the Trade and Companies Register of LYON under number 479 560 013, 

Represented by Mr. Gil BEYEN in his capacity as Chairman and Chief Executive Officer 

Hereinafter referred to as “The Lessee” 

The Lessor and the Lessee being hereinafter together referred to as the
“Parties”         
 and individually as the “Party”. 

IT HAS BEEN AGREED AND DECIDED AS FOLLOWS: 

The Lessor as owner leases and grants for rent to the Lessee, which accepts, by this commercial lease the leased premises designated in Article 1 under the
conditions of Articles L. 145-1 through L. 145-60 forming chapter V of the Commercial Code and Articles R 145-1 et seq. of the same code, and under the specific and general conditions which have been expressly agreed in the following articles. It is
specifically stated that the specific conditions prevail over the general conditions. As a result, in the event of any difficulty of interpretation or conflict between the general conditions and the specific conditions, the specific conditions shall
prevail in all circumstances, which the Parties expressly acknowledge. 

 PREAMBLE 

Under the terms of a private agreement with effect from September 24, 2007, LYON 2006 INVESTORS SAS granted a lease to the Lessee, ERYTECH PHARMA SA, in
a housing complex named “ADENINE”, located at 60 avenue Rockefeller – 69008 LYON, the description of the premises of which is the following: 
  

	 	•	 	On the ground floor and on the 5th floor of the building, various rooms for use as offices and laboratories with a share of the common area included of
approximately 924.10 m2, an area of 46 m2 for use for archives in the basement, and 2 outside parking spaces and nine parking spaces in the
basement. 

 Under an addendum No. 1 to the lease with effect from August 25, 2008, the lessor and the lessee agreed to lease
additional premises, described as follows: 
  

	 	•	 	On the 4th floor of the building, various rooms for office use with a share of the common area included of approximately 399.23 m2 with 1 outside parking space and 4 parking spaces in the basement. 

 Under an authentic
instrument dated August 8, 2012, SCPI PFO2 acquired the “ADENINE” housing complex and due to this it became subrogated to the rights of the Lessor. 

ERYTECH PHARMA recently informed JONES LANG LASSALLE of its interest in taking a lease of an additional surface area of approximately 430 m2 on the 1st floor of the “ADENINE” housing complex and 6 parking spaces in the basement and 1 outside parking space. 

For this purpose, the Parties agree to sign at the same time an amicable early termination instrument as of 06/30/2015 related to the above-mentioned lease
and to agree to this new lease with effect from 07/01/2015 on all of the surface areas. 
 I- DESCRIPTION 

1) LEASED PREMISES 
  

			
	 •       Address:
	  	See Article 3 below

 60 avenue Rockefeller – ADENINE Building – 69008 LYON 

 

			
	 •       Description:
	  	

 The leased premises, (including a share of the common areas) consist of: 

 

	 	•	 	premises for office and office-laboratory use; 

  

	 	•	 	Ground floor: approximately 477.10 m2 leased (office-laboratories) 

 

	 	•	 	Ground+1: approximately 430 m2 leased (office-laboratories) 

  

	 	•	 	Ground+4: approximately 399.23 m2 leased 

  

	 	•	 	Ground+5: Attic: approximately 447 m2 leased (office-laboratories) 

 

	 	•	 	Archives areas in basement level -1 which is 46 m2 leased 

  

	 	•	 	Provision of a closed area specific to laboratory wastes, can be shared among the different tenants in the building and located on the ground floor 

 

	 	•	 	Parking spaces: 

  

	 	•	 	19 parking spaces in the basement numbers 1 – 22 – 31 – 35 – 36 – 45 – 52 – 53 – 54 – 55 – 56 – 57 – 59 – 60 – 61 – 62 – 63
– 64 – 66 

  

	 	•	 	4 outside parking spaces numbers 73 – 74 – 75 - 81 

 The common areas include the
landings, entrance hall, elevators, stairways, toilets, and movement space on every level... 

 II- SPECIFIC CONDITIONS 

The specific conditions apply by derogation from the general conditions. 

2.1 – Term 
 See Article 4 below 

 

			
	 •       Nine years beginning from:
	  	07/01/2015
		
	 •       Date of end of lease:
	  	06/30/2024

 2.2 – Purpose – Authorized Activity 

See Article 5 below 
  

	•	 	exclusive use of offices and offices-laboratories for the activities defined as of this date by its corporate purpose. 

  

			
	2.3 – Annual Principal Rent (excluding taxes)	  	€ 321,760.

 (Three hundred and twenty one thousand seven hundred
and sixty euros) 
 See Article 6 below 

2.4. – Mobile Scale Clause 
 See
Article 7 below 
  

			
	 •       Date of first annual indexing:
	  	07/01/2016
		
	 •       Basic Index: TARI
	  	4th quarter 2014 – 107.80

2.5 – Fees 
 See Article 8
below 
  

			
	 2.5.1 – Quarterly Provision for Current Fiscal Year:
	  	€ 34,014.

 (THIRTY-FOUR THOUSAND FOURTEEN EUROS) 

 

			
	including	  	Provisions on operating fees: € 20,591
		
		  	Provisions on real estate tax and additional taxes: € 13,423

 These
provisions are calculated on an all taxes included budget and the VAT will be shown when fees and taxes are adjusted. 
 2.5.2 – Rules on
Distribution of Fees and Taxes 
 The Lessee shall pay a share of fees and taxes in the following proportions: 

See appendix related to the budget of provisional fees 

2.6 – Tax Rules 
 See Article 9 below

 VAT (Lessor’s option-Article 260-2 General Tax Code) 

2.7 – Security Deposit 
 See Article 10
below 
  

			
	 Equal to three months of the rent, which is:
	  	€ 80,440

 (EIGHTY THOUSAND FOUR HUNDRED FORTY EUROS) 

2.8 – Transfer of Security Deposit 
 The
amount of the security deposit currently held by the Lessor, which is € 73,684.89, for the lease with effect from September 24, 2007 related to the premises located in the housing complex named “ADENINE” and subject to an early
termination with effect from June 30, 2015, shall be transferred to the new security deposit account to be established for this lease. 
 As a
consequence, by derogation from Article 10.1, the Lessee shall pay an additional security deposit in an amount of € 6,755.11. 

 2.9 – Rent Exemption Excluding Tax/Excluding Fees 

The Lessor grants to the Lessee an exemption from rent for 3 months excluding recoverable fees and taxes, establishing for the Lessee a rent reduction granted
by the Lessor as an exception and purely commercial. As a consequence, the rent shall be due only beginning on October 1, 2015, the fees will be due beginning on July 1, 2015. 

2.10 – Lease Term 
 By derogation from Article
4.3 of the General Conditions and by express derogation from Article L. 145-4, 1st paragraph of the New Commercial Code codified, the Lessee expressly and irrevocably waives the right to leave at
the expiration of the first three year period. 
 The Lessee may then leave for the first time upon expiration of the fourth year, which is for
June 30, 2019 then at the expiration of the sixth year and of the ninth year of this lease in the forms and time period set forth in Article 4.3 below. 

2.11 – Construction Work at Expense of the Lessee  

The Lessor authorizes the Lessee at this time to carry out, at its expense and under its responsibility, construction work on improvements and access in the
premises, under the following conditions: 
  

	 	•	 	Authorization granted to the Lessee to use the emergency staircase in access for the areas on the 1st floor, it being understood that such access shall comply with
the regulations in effect, specifically in terms of fire safety. 

  

	 	•	 	Creation of a freight elevator, with a reserved surface area of approximately 1 m2 between the ground floor and the
1st floor of the leased premises. The Lessee agrees to bear all consequences of such construction work which might be harmful to the structure and solidity of the building, to any electrical and
fluid connection, to hold the Lessor harmless from any damage of any nature whatsoever which is caused by the performance of such construction work. 

  

	 	•	 	Creation of an access door for deliveries of the Lessee on the ground level of the real estate complex, including modification of the facade. The Lessor authorizes the Lessee to carry out all necessary administrative
actions in order to obtain the legal and official authorization to modify the facade on the ground level. 

 The Lessee is reminded that,
for all of the construction work referred to above, it shall provide to the Lessor, for approval, all technical descriptions, approved by an architect and a BET structure. In parallel, the authorizations of the Lessor cannot in any case render the
Lessor liable or reduce the liability of the Lessee between the Parties as well as with respect to third parties. The construction work shall be done at the expense of the Lessee, under its responsibility and within the industrial practice. The
Lessee, upon accepting the work, shall provide to the Lessor all DOEs and Records of acceptance of the work. 
 The Lessee shall also retain
responsibility for cabling for computer technology and telephones. 
 2.12 – Negotiation Professional Fees 

The parties acknowledge that this transaction was completed through the intermediary of the JONES LANG LASALLE company domiciled at 55 avenue Foch – 69006
LYON, and that the professional fees of this company, for which the Lessee is responsible totals 8% of the annual rent excl. taxes, which is the amount of € 25,740.80 + V.A.T. at the current rate of 20%. These professional fees shall be payable
on the date of signature of the lease. 
 2.13 – Electric Service Contract 

The Lessor shall take personal responsibility for any request to the service providers concerned regarding its request for a meter based on its electric power
requirements, the service contract and the supply of fluids and the electrical connection of the leased premises. 
 The Lessee expressly agrees to
provide to the Lessor and at its request the copy of its energy consumption bills. 

 2.14 – Premises and employees Consumption of fluids and waste production 

The Lessee agrees to transmit to the Lessor, at least annually, the information on actual fluid consumption (water, electricity, gas, heating fuel, etc.)
related to the leased premises and the quantities of wastes produced if known. 
 If applicable, the Lessee shall inform the Lessor of any accident,
incident or event that occurred in the premises which is likely to explain any significant and exceptional increase or reduction found in the level of such consumption. 

The Lessor shall be able to have communicated to it the average number of employees working in the Premises and the regular time slots of use of the Premises
and the list of specific equipment with a capacity over or equal to 1000 W that it operated. 
 2.15 – Attached Documents 

The following informational documents are sent by the Lessor to the Lessee, which acknowledges it: 

 

	 	•	 	1. The report on natural, technological and mining risks dated 01/14/2015. 

  

	 	•	 	2. The accurate and exhaustive inventory of categories of expenses, taxes, fees and payments with distribution between the Lessor and the Lessee 

 

	 	•	 	3. The provisional report of construction work planned by the Lessor in the first three years after the lease is entered into with a provisional budget and in the 3 years preceding the conclusion of the lease with their
cost. 

  

	 	•	 	4. Plans of the premises and parking areas. 

 III – GENERAL CONDITIONS 

3) DESCRIPTION AND REPORT ON CONDITION OF PREMISES ON ENTRY 

3.1 – The Lessee declares that it has full knowledge of the leased premises described below in Article 1 because it has seen and visited the premises. The
Lessee exempts the Lessor from giving a more specific description of it and accepts the premises in their current condition, as they exist and together with their easements and appurtenances. 

The Lessee also agrees to not dispute the surface area which does not constitute an essential element of its consent. 

It is expressly agreed that any error in the description of the leased premises shall not justify any reduction or increase of rent, which has been
specifically set based on the overall evaluation and perfect knowledge of the premises leased by the Lessee. 
 Any difference between the surface areas
indicated in the Specific Conditions or in annexes and the actual dimensions of the leased premises shall not justify any reduction or increase of the rent. 

It is the mutual intention of the Parties that the leased premises expressly form an indivisible whole. 

3.2 – In accordance with Article 145-40-1 of the Commercial Code, a report on the condition of the premises has now been drafted for the ground level,
the ground level + 4 and +5, when the preceding lease was made. A report on the condition of the premises for the ground level + 1 shall be prepared when possession of the leased premises is taken in the presence of both parties and amicably by the
Parties or by any third party authorized by the parties. One-half of the costs of this report shall be borne by each Party. 
 If there is no amicable
report on the condition of the premises in the presence of both parties, it shall be drafted by a court bailiff, at the initiative of the most diligent Party, the other Party having been duly summoned to attend it. The cost billed by the court
bailiff to draft this report shall be shared equally between the Lessor and the Lessee. 
 The report on the condition of the premises is attached to this
lease or, if it is not, is kept by each of the Parties. 
 The Lessor may be represented at this inspection of the premises by its manager or by a
specialized company or any other person of its choice. 
 3.3 – The Lessee agrees not to bring any action against the Lessor for defects, or apparent
defects or failures. 

 4) TERM 

4.1 – The lease is granted for a period of nine full and consecutive years, which will begin to run from the effective date set forth in Article
2.1 above. 
 4.2 – The lease shall terminate upon expiration by the effect of a notice given by registered letter with a request for
acknowledgment of receipt or by extrajudicial instrument six months in advance by either Party in the forms and time periods in Article L. 145-9 of the Commercial Code. If it is not terminated, the lease shall continue beyond the fixed term and
shall terminate only by the effect of a notice given by registered letter with a request for acknowledgment of receipt or by extrajudicial instrument at least six months in advance for the last day of the calendar quarter. 

4.3 – The Lessee shall be solely authorized to terminate the lease at the expiration of each three year period, and the Lessee is responsible for
giving notice to the Lessor six months in advance by registered letter with a request for acknowledgment of receipt or by extrajudicial instrument. 

4.4 – When the notice is given by registered letter with a request for acknowledgment of receipt, the date of the notice is the date of the first
submission of the letter in accordance with Article 145-1-1 of the Commercial Code. 
 4.5 – The Lessor may terminate this lease at any time
without compensation in the case of construction work made mandatory by the Administration and/or by regulations requiring the total release of the leased premises or when the leased premises can no longer be used by the Lessee without danger. 

5) INTENDED USE – AUTHORIZED ACTIVITY 
 5.1
– The Lessee shall use the leased premises in accordance with the intended use and exclusive assignment which have been given to them by the Lessor in Article 2.2 above. 

5.2 – The Lessee shall take personal responsibility, at its expense, risk and peril, for any consequences that may result from the activity
conducted in the premises; for this it agrees to: 
  

	 	•	 	to comply with the regulations in effect at the time of the lease and throughout its performance, 

  

	 	•	 	to obtain all administrative or other authorizations necessary to its activity, and their renewal throughout the term of the lease, 

  

	 	•	 	to pay all taxes and fees, 

  

	 	•	 	to carry out all construction work and improvements to comply with any applicable regulations as of the date when the lease is entered into or during its performance, 

 

	 	•	 	and, generally to do what is necessary so that the Lessor is never held responsible or liable regarding its activity. 

5.3 – The Lessee shall not conduct in the leased premises any activity which is of a hazardous or unsanitary nature, contrary to public order or
good morals, or carried out in violation of legislation or regulations. 
 5.4 – The Lessor does not guarantee any exclusivity or
non-competition of any kind whatsoever, specifically commercial. 
 The Lessee waives any right of action against the Lessor and its agent and specifically
any claim for compensation and/or reduction and/or arrangement of rents and/or fees for this purpose. 
 6) RENT 

6.1 – The principal annual rent set forth above in Article 2.3 shall be payable in advance and by quarter on the first day of each calendar
quarter, at the address of the Lessor or its agent and for the first time, as of the effective date of the lease set forth in Article 2.1. 

 The first term shall be calculated on a prorata temporis basis between the effective date of the lease and the
last day of the current calendar quarter on the effective date of the lease. 
 6.2 – The payment shall be made by check, by bank or postal wire
transfer or by withdrawal from the Lessee’s account, but in no case by using notes or commercial paper. 
 7) MOBILE SCALE 

7.1 – The principal rent set forth in Article 2.3 above shall vary upon expiration of each lease year, higher or lower, automatically and without
formalities, in the same proportions as the Tertiary Activities Rent Index (TARI) published by the INSEE (Institut national de la statistique et des études economiques [National Institute of Statistics and Economic Studies]). 

7.2 – The base index is indicated above in Article 2.4. Upon expiration of the 1st lease
year, the rent shall be indexed based on the most recent published index, compared to the base index. Then, upon expiration of each lease year, the rent shall be indexed based on the most recent published index, compared to the index used for the
previous indexing. 
 7.3 – This mobile scale clause is an essential condition of the lease for the Lessor, without which it would not have been
made, which is expressly accepted by the Lessee. As a consequence, if the index used is no longer published, the Parties decide to refer to the replacement index, or to any other index selected by them by mutual agreement; if not, the replacement
index shall be determined by the competent Court. 
 7.4 – In the event that any of the provisions of this article is held to be void or
inapplicable, such nullity shall not affect the other lease provisions or the rule on annual indexation of the rent. 
 8) CHARGES, TAXES AND
FEES 
 8.1 – The Parties intend that the principal rent set forth above is stipulated net of all charges, fees, taxes, user fees and
work for the Lessor, except for expenditures which due to their nature can be charged to the Lessor as exclusively listed in Article R. 145-35 of the Commercial Code and listed below: 

1° Expenditures related to the large repairs referred to in Article 606 of the Civil Code and to professional fees related to the performance of such
work, if any; 
 2° Expenditures related to construction work for the purpose of repairing obsolescence or to bring the leased property or the building
in which it is located into compliance with regulations, when they are large repairs referred to in the preceding paragraph; 
 3° Taxes, specifically
the territorial economic contribution, fees and user fees of which the person liable is the lessor or the owner of the premises or building; however, the real estate tax and taxes in addition to the real estate tax and taxes, fees and user fees
related to use of the premises or the building or to a service from which the tenant benefits directly or indirectly may be charged to the tenant. 
 4°
The professional fees of the lessor related to management of rents of the premises or building subject to the lease; 
 5° In a housing complex, the
expenses, taxes, fees and user fees and cost of construction work related to vacant leased premises or which can be charged to other tenants. 

Expenditures related to improvement construction work the amount of which exceeds the cost of identical replacement are not included in the expenditures
referred to in 1° and 2°. 
 8.2 – As a result, the Lessee shall repay, specifically, to the Lessor: 

8.2.1 – Local taxes, including the real estate tax and its additional fees, the fee for removal of household garbage, the sweeping fee and, if
applicable, the annual tax on offices, and, generally all current, future or replacement taxes and fees related to the leased premises or to the building attached to the leased premises to the extent that they are connected to the use of the leased
premises or building or to a service from which the Lessee benefits directly or indirectly, even when they would in principle be borne by the Lessor. 

 8.2.2 – The costs of supplies and individual consumption by the Lessee, in addition to those related
to the share of common areas, water, electricity, gas, heating and air conditioning. 
 8.2.3 – The costs of services and provisions related to
the building or leased premises, namely: 
 The costs of services and provisions of the building or leased premises, specifically: guard service –
access control – digital code, intercom, video monitoring, employee salaries and social security contributions and taxes – cleaning and maintenance of common areas – window cleaning, cleaning facades of the building, sanitation
and cleaning supplies, employee salaries and social security contributions and taxes, rat extermination, disinfection, insect extermination, snow removal – maintenance of green spaces – replacement and planting of plants-,
maintenance of parking areas outside and in the basement, of courtyards, repainting and coating of floors and ceilings of common areas. 
 ASL, AFUL,
co-tenancy, associations and RIE fees, if applicable, maintenance and partial restoration of roofs, maintenance and restoration of doors and doorways, sign maintenance, waste removal- rental of waste dumpsters, supplies of bags, containers,
employee salaries and social security contributions and taxes, VMC contracts, lifting pumps, fluid consumption – electricity, cold water, hot water, ice water, fuels-, expenses related to maintenance, supply, renovation of heating,
air conditioning installations, maintenance of columns – cold water, hot water, ice water, gas -, contracts – extinguishers, smoke removal, RIA, dry column, BAES -, maintenance of various pipework, networks for waste water
evacuation, multi-technical contracts, mandatory inspections of installations and equipment, audits, insurance deductible in case of accidents in common areas, expenses related to maintenance, repairs, renovation of elevators, freight elevators, car
elevators, partial repair of walls and vaults. 
 8.2.4 – All expenses common to the real estate complex of which the leased premises are a
part, including costs and professional fees of technical management of the building or leased premises, costs and professional fees of audits and technical inspections incurred by the Lessor, insurance premiums and additional insurance premiums of
the building, maintenance work, repairs, replacement and of checking of all equipment and installations of the leased premises and the building. 

8.3 – An accurate and exhaustive inventory of these expenses, fees, taxes and user fees containing the indication of their division between the
Lessor and the Lessee is attached to the lease in accordance with Article L. 145-40-2 of the Commercial Code. This inventory appearing in the annex is an integral part of the lease and binds the Parties. 

This inventory shall give rise to an annual summary report sent by the Lessor to the Lessee no later than September 30 of the year following the year for
which it is prepared or, for buildings in co-tenancy, within a period of three months from the statement of co-tenancy expenses for the annual fiscal year. 

If applicable, invoices corresponding to this summary report may be sent by e-mail or consulted, upon request, at the domicile of the building manager. 

During the lease, the Lessor shall inform the Lessee of any new charge, tax, fee and user fee. 

The Lessee shall be liable for any new charge, taxes, user fee and fee. 

The charges, taxes and fees shall be divided on a prorated basis of general fractions allocated to the leased premises, and if not, at the prorated surface
area of the leased premises (including share of common areas) compared to the total surface area of the building. 
 The Lessor shall keep the Lessee
informed during the term of the lease of any information which is likely to change the division of charges, taxes and fees. 
 8.4 – The
provision on charges set forth above in Article 2.5 for the current fiscal year shall be paid each quarter in advance at the same time as the principal rent and in the same conditions. 

The first term shall be calculated prorata temporis between the effective date of the lease and the last day of the current calendar quarter on the effective
date of the lease. 

 The quarterly provision on expenses shall be calculated annually based on the provisional budget of expenses of
the relevant fiscal year and based on the share of the leased premises leased by the lessee in the various codes for dividing such expenses. 
 The
quarterly provision for real estate taxes and additional taxes shall be calculated annually based on the actual share of the leased premises of the preceding year leased by the lessee increased by a revaluation rate determined annually. 

The quarterly provision for taxes on offices and parking spaces shall be calculated annually based on the actual share of premises leased in the preceding
year leased by the lessee increased by a revaluation rate determined annually. 
 Provisions are called every quarter and payable quarterly in advance. They
correspond to the share of surface areas leased (including share of common areas) in the annual provisional budget. 
 These provisions shall be deducted
from the amounts of actual expenses and taxes calculated and collected annually. 
 8.5 – The Lessor shall prepare the accounting of expenses by
calendar year. A breakdown shall be sent to the Lessee with attached documentation no later than September 30 of the year following the year during which the expense was incurred and within 3 months from the annual statement of co-tenancy
charges for a building in co-tenancy. If applicable, the invoices may be consulted, by appointment, at the address of the building manager. 
 8.6
– The Lessor reserves the ability to modify the division of expenses and construction work, specifically in the event of any change in the use of the facilities, of elimination or any new facility, and in the event of modification of the
building, of the division of lots among Lessees and co-owners or of legislation. 
 The Lessor agrees to inform the Lessee of any division modification.

 In addition, the division among tenants of expenses, taxes, fees and user fees and of the cost of construction related to the real estate complex may be
weighted by agreement. The Lessee is informed of such weightings. 
 8.7 – The construction work completed and planned by the Lessor is attached
to the lease: 
 1° A provisional report of the construction work that the Lessor plans to carry out in the three years after the lease is concluded,
with an attached provisional budget. 
 2° A summary report of the construction work that the Lessor completed in the three years prior to the
conclusion of the lease, indicating their cost. 
 The Lessor shall communicate to the Lessee every 3 years within the period of 2 months beginning from the
end of each three year term of the lease in accordance with Article R. 145-37 of the Commercial Code these two summary reports related to the work. 
 9)
TAX RULES 
 9.1 – Rents, taxes, fees, expenses and related charges shall be increased by the VAT under the conditions and at the rate in effect on
the date of each billing, as the Lessor has opted for the VAT tax rules in application of Article 260 – 2° of the General Tax Code. 
 9.2 –
The Lessee shall pay to the Lessor, all other new, additional or replacement fees in the event that the option for the VAT rules cannot be maintained, or if the VAT is eliminated, as the rent is stipulated net of all charges. 

 10) SECURITY DEPOSIT 

10.1 – In order to guarantee at all times the proper performance of payment obligations and the performance of all of the clauses and conditions of the
lease for which the Lessee is responsible, the Lessee pays, upon signature of this lease, to the Lessor, a security deposit, which does not produce interest, the amount of which, equal to three months of the annual rent excluding taxes and excluding
charges, is indicated in Article 2.7 above. 
 10.2 – This security deposit shall be kept during the entire lease term. The security deposit shall be
increased or reduced upon any variation of the annual rent, in the same proportions, so that it is at all times equal to three months of such annual rent excluding taxes and excluding charges. 

10.3 – The security deposit shall be returned at the end of possession, after the accounting of charges, taxes and repair work is approved, after
deduction of any amounts which may be owed by the Lessee for rents, charges, taxes, fees, occupancy payment, related costs, work, penalties, late payment interest, repairs or for any others which the Lessee may owe to the Lessor, or for which the
Lessor may be rendered liable for it for any reason whatsoever, during the lease and/or during any automatic extension and until the Lessee moves out and returns the keys, if this occurs after the lease expires. 

The security deposit shall not in any case be applied by the Lessee, in full or in part, to any of the rent payments, occupancy payment, charges, taxes and/or
to any other related costs owed for this lease. 
 10.4 – It is acknowledged by the Lessee that the security deposit paid constitutes a cash collateral
with dispossession as provided in Articles 2 333 et seq. of the Civil Code and that as a consequence the Lessor shall be authorized, at any time whenever during the lease or upon expiration of the lease, to take and use the security deposit, without
formality, for the payment by set off of amounts owned by the Lessee for rent, occupancy payment, charges, taxes, fees, related costs, penalties, construction work or other costs. 

In this case, the Lessee shall be obligated to reestablish this deposit upon request by the Lessor within a period of 30 days except in the case of a serious
dispute, the Lessee expressly agreeing to the set-off for this purpose. 
 10.5 – In the event that a safeguard proceeding, court-ordered restructuring
or court-ordered liquidation is opened, it is acknowledged by the Lessee that the debt receivable by the Lessor for secured obligations in the case of non-payment and the debt receivable by the Lessee on the Lessor to return the security deposit are
related. The Lessor may, if it deems it appropriate, automatically and without formality, set off from any debt prior to the decision to open the proceeding with all or part of the security deposit it holds, and in the amount due. 

In this case, the continuation of the commercial lease by the court administrator or liquidator in that capacity under Articles L. 622-13 et seq. of the
Commercial Code shall have as a mandatory and immediate consequence the obligation by the Lessee (or even by the court administrator or liquidator) or its successor to re-establish the security deposit, independent of the payment of rents, charges,
fees, taxes, related costs or other costs, subject to the penalty of the termination clause in Article 19 below, if the Lessor deems it appropriate. 
 10.6
– In the case of termination of this lease by the Lessee other than expiration of a contractual term, whether the cause is judicial or under the effect of the termination clause in the lease, automatically or if it results from the application
of a legal provision, the entire security deposit shall remain acquired by the Lessor solely due to such termination, without prejudice to any damages or compensation. 

10.7 – In the case of assignment of the right to the lease or business assets, the security deposit shall be retained by the Lessor and shall be returned
to the assignor only after payment of any amounts owed by the assignor. Thus, the assignee shall be obligated to pay to the Lessor, on the date of signature of the assignment, the amount of the security deposit due in performance of the lease. 

10.8 – In the case of sale of the building of which the leased premises are a part, the security deposit shall be transferred by the Lessor to the
purchaser of the Building which shall become the sole debtor to the Lessee which the Lessee acknowledges. The Lessee agrees to claim the return only from such purchaser. 

 11) LATE PAYMENT INTEREST 

11.1 - By express agreement, any sums which owed by the Lessee under this lease not paid at their due date shall carry automatically interest payable to the
Lessor, at the legal rate increased by five points, as from the date of the aforesaid due date, without it being necessary give prior formal notice. 
 The
application of the preceding subparagraph, shall not at any time, be regarded as constituting authorization of any delayed payment. It shall not in any way prevent the termination action referred to in Articles 19.1 and 19.2 infra. 

11.2 - However, such interest shall not be invoiced if the Lessee paid its debt within fifteen days of the due date. 

12) USE OF THE PREMISES 
 12.1 - The premises shall
be constantly furnished by the Lessee with pieces of furniture and materials in sufficient quantity and value to meet at any time the payment of the rents and related expenses as well as performance of the clauses and terms of the lease. 

12.2 - The Lessee shall maintain the occupancy of the premises continuously, and ensure their permanent operation. 

12.3 - The Lessee shall comply with all current and future laws, regulations and practices in effect and in particular all regulations on the roadway system,
police, safety, town planning, health, environment, with the regulations of the labor law and the regulations relating to the establishments receiving the public. 

The Lessee shall comply, as applicable, with the provisions of the joint ownership rules, the specifications of bylaws of associations or the building rules
as well as with any decisions made in the general interest by the Lessor or the meetings of joint owners or shareholders. 
 The Lessee shall thus be
responsible, at its sole expense, to respond to any administrative injunctions and regulations, so that the Lessor is never held liable. 
 12.4 - After
obtaining the prior written consent and of the Lessor related to the site, quality, materials, dimensions and the methods of installation, the Lessee shall be able to affix at its expense signs, posters, banners, formwork, plates, signs, antennas,
parabolas or others outside the lease premises, or visible from the exterior, only on the windows. 
 The Lessee shall take responsibility for all
obligations, in particular administrative obligations and for the payment of any taxes. 
 The Lessee agrees to deposit them, at its expense and without
delay, at the end of the lease or upon any request by the Lessor, in particular in the event of construction work and to carry out all necessary repairs. 

12.5 - The Lessee shall not be able to deposit, even temporarily, in the common areas of the building, as they must remain permanently free. No encroachment
on the common areas shall be authorized. 
 12.6 - The Lessee shall take all appropriate measures so that the exercise of its activities does not disturb
the peace, good appearance or maintenance of the building, and does not cause any nuisance for neighbors. Particularly, the Lessee shall not be able to use any means of broadcasting (loudspeakers, etc.) which can be heard outside of the leased
premises. Devices and installations which can cause any disturbances shall have to be “anti-parasitized” or isolated; “lost water” air-conditioners are prohibited. 

The Lessee shall not bring inflammable, explosive, corrosive or dangerous materials into the leased premises, or use gas or slow combustion devices. 

The Lessee shall pay attention to the proper conduct of its staff and visitors, it being understood that the Lessee shall be held responsible for any damage
committed in the building and in the leased premises by its staff or visitors. 

 The Lessee shall indemnify and hold the Lessor harmless from any claim or action by any third party against the
Lessor (in particular by neighbors) for any nuisance caused by the Lessee or its employee. 
 12.7 - The Lessee shall not be able to load the ground and
floors with a weight over 250 kilos per m2. Any load beyond this limit shall be subject to prior written authorization by the Lessor. 

12.8 - The Lessee shall not be able to carry out in the premises any work, changes of distribution, demolitions, borings of walls or vaults, or construction
without prior written consent of the Lessor. For this purpose, the Lessee shall send to the Lessor all useful documents, (plan, description, technical notes, etc.) and the work shall be carried out under the oversight of an architect or an
engineering firm, approved by the Lessor, at the expense and risks of the Lessee. 
 12.9 - All work, improvements, facilities, installations and
construction, including partitions, carried out by the Lessee at the time of entry into the premises or during the lease shall become the property of the Lessor in the end of this lease, by way of accession, without compensation, unless this
requires the delivery of the premises in their original state, in whole or in part. The same shall apply to any equipment intended to be immovable. 
 12.10
- Public sales are rigorously prohibited in the leased premises and the common areas of the real property including as a part of a collective proceeding. 

12.11 - In the event of necessity for the Lessor, the Lessor may temporarily or permanently limit or prohibit the access to all or part of surface area of
common areas. This limitation or prohibition of use of common areas shall not cause a deduction of rent or compensation for the Lessee, except in the event of a substantial obstacle to the access to the leased premises. 

13) MAINTENANCE 
 13.1 - The Lessee shall take the
leased premises in as is condition, without being able to claim from the Lessor whether it is upon entry in the premises or during the lease any work, bringing into compliance, building out or installations of any kind whatsoever except for the work
referred to in Article R. 145-35 of the Commercial Code in its subparagraphs 1 and 2. 
 13.2 - The Lessee shall maintain the leased premises in perfect
condition for the length of lease and it shall make any necessary maintenance repairs regardless of the nature; the Lessor shall retain responsibility only for major repairs defined by Article 606 of the Civil Code except in cases where: 

 

	 	•	 	they are due to a maintenance failure which is the responsibility of the Lessee 

  

	 	•	 	they are related to improvement work the amount of which exceeds the cost of identical replacement within the meaning of Article R. 145-35 of the Commercial Code. 

The Lessee shall particularly ensure the perfect operating condition and cleanliness of doors, closures, shutters, curtains, blinds, windows and frame, taps,
drains, it shall repair their painting if necessary. 
 It shall also maintain and repair the walls, partitions, ceilings and coatings of the floors as
often as necessary, so as to always keep them in a perfect state of cleanliness and maintenance, except if this work results from a failure of the Lessor as to its obligations for work for which it is responsible set forth in Article 606 of the
Civil Code. 
 13.3 - The Lessee shall maintain the equipment and installations in the leased premises or serving them exclusively; it shall carry out as
necessary their modification, repair or replacement or bringing them into compliance, even if it results from new standards or regulations, all at its expense and so that this equipment and installations are returned at the end of the lease in
perfect compliance and operating condition. For this purpose, it shall subscribe all necessary service contracts and shall have periodic inspections of the proper operation of such equipment and installations, as well as their conformity to the
standards in force and the provisions of the Labor Code, in particular regarding safety, carried out by licensed entities. 

 13.4 - In all the cases where the obligations above subject to Articles 13.1 to 13.3 are not met, the Lessor
shall be able, one month after a formal notice remains without effect, to complete necessary work using any company of its choice and under the oversight of a project manager, to sign maintenance service contracts or to have inspections conducted,
all at the expense of the Lessee. 
 13.5 - The Lessee shall bear the cost and allow any repair work, renovation, rebuilding, heightening and enlarging
which the Lessor has to have carried out in the leased premises or the building of which the leased premises is a part without compensation, regardless of the disadvantages and duration even if they exceed a duration of 21 days notwithstanding the
provisions of Article 1724 of the Civil Code. 
 The Lessee shall also pay the costs, if any, without compensation, of cabling, ducts, and channeling
necessary for service of other leased premises in the building, and any installations intended to ensure the safety of the building or to improve the comfort of the building. However, in all the cases work shall be carried out with all necessary
diligence. 
 13.6 - The Lessee shall allow the Lessor, its representatives and companies to enter the leased premises for the determination and to complete
work deemed appropriate, in accordance with Articles 13.4 and 13.5 above, with 48 hours’ notice, except in case of an emergency. 
 14)
DOMICILIATION - SUBLEASING 
 14.1 - Any domiciliation is prohibited except with prior written consent of the Lessor. 

14.2 - The Lessee shall not replace any person or company, even without consideration, in the leased premises, in whole or in part. The Lessee shall
personally occupy the leased premises. 
 14.3 - The Lessee may to sub-lease the leased premises, in whole or in part, only with the prior written approval
of the Lessor. 
 14.4 - In the case of authorized subleasing, it may take place only by an instrument in which the sub-tenant acknowledges the indivisible
character of the principal lease and agrees jointly and severally with the Lessee, within the limit of its sub-lease, to the payment of the principal rent and the performance of the terms of the principal lessee. This sublease shall be notified to
the Lessor at no cost to the Lessor in the month in which such sublease takes effect, at the latest. 
 14.5 – Non-compliance of these obligations and
conditions subject to Articles 14.1 through 14.4 above shall immediately and automatically cause termination of the principal lease. 
 15) ASSIGNMENT

 15.1 - The Lessee may assign its right to the lease only to the purchaser of the assets operated in the leased premises. The assignee shall be
approved in advance by the Lessor. 
 15.2 - In this case, the assignment shall occur only to the extent that any sums billed and owed pursuant to this
lease are paid in advance; moreover, the Lessee shall be obligated to notify at its expense by registered letter with a request for acknowledgment of receipt or by extrajudicial instrument to the Lessor, at least fifteen days in advance, the draft
of the deed of sale constituting an assignment of the right to the lease. In addition, the Lessor shall be requested to concur in the instrument by the same notification. Finally, the assigning Lessee shall be liable to the Lessor for compensation
representing the cost of the possible repair work or of bringing the leased premises into compliance as they shown by the report on the condition of the premises referred to in Article 15.3 below. This compensation shall represent the amount of the
estimates of work corresponding to repairs or bringing the premises into compliance shown by comparison between the report on the condition of the premises of intermediate exit and the original report on the condition of the premises. 

15.3 - In accordance with Article L. 145-40-1 of the Commercial Code, in the event of assignment of the right to the lease, assignment or transfer without
consideration of business assets, a report on the condition of the premises shall be prepared in the presence of both parties and amicably between the parties or by a third party authorized by them before the entry into possession of the leased
premises by the Assignee. 

 The Lessee shall be obligated to inform the Lessor by registered letter with a request for acknowledgement of
receipt of the effective date of possession of the leased premises by the assignee at least 15 days before this date, so that the Lessor can usefully organize the inventory of fixtures of entry in the leased premises by the assignee. 

One-half of the costs of this report on the condition of the premises shall be borne by each Party. 

If there is no amicable report on the condition of the premises in the presence of both parties, it shall be prepared by a court bailiff, at the initiative of
the most diligent party, with expenses shared equally between the Lessor and the Lessee. 
 The report of the condition of the premises on intermediate exit
shall be attached to this lease or, if it is not, shall be kept by each Party. 
 The Lessor may be represented at this inspection by its manager or a
specialized company or any other person of its choice. 
 15.4 - The Lessee in the event of assignment or transfer without consideration of the lease or the
business assets, shall remain a joint and severally liable guarantor with respect to the Lessor for the payment of rents or occupancy compensation, for expenses, tax bills, taxes and any sum due pursuant to the lease as well as full performance of
the clauses and terms of the lease, for 3 years from the signature of the instrument of assignment or transfer, provided that notice of it is given to the Lessor within 15 days of the assignment or transfer by registered letter with a request for
acknowledgment of receipt. In addition, the assignee shall be with respect to the Lessor a joint and several guarantor of the Assigning Lessee for the payment of rents and expenses due until the date of the assignment, even if they are billed later.
Any act of sale constituting an assignment of the right to the lease shall mention these obligations; these provisions shall apply to any successive assignments. 

The Lessor shall be obligated to inform the Assignor of any failure by the Assignee to pay within a period of one month from the date on which the amount
should have been paid by the Assignee. 
 15.5 - In the event of assignment, as in the event of merger or split of companies, of partial contribution of
assets, of universal transfer of assets or transfer of more than 50% of the corporate shares, an original of the instrument shall be served on the Lessor at no cost to the Lessor, within the period of 15 days from the transaction. 

15.6 - The Lessee shall grant in a financial lease the business assets operated in the leased premises only with the prior written authorization of the
Lessor, which shall be granted in a reasonable time period. The refusal of the Lessor shall be based on fair reasons. 
 15.7 – Non-compliance with the
obligations above subject to Articles 15.1 through 15.6 shall immediately and automatically cause termination of the lease. 
 16) INSURANCE

 16.1 - The Lessor guarantees the financial consequences of civil liability that it may incur as owner. It insures the building of which the LEASED
PREMISES are a part as well as all improvements and installations in the nature of real property which it owns, specifically against risks of fire, explosions and special risks such as: 

 

	 	•	 	water damage, 

  

	 	•	 	storm, wind, hail, weight of snow and ice 

  

	 	•	 	riots, attacks, terrorism, sabotage, 

  

	 	•	 	malice, vandalism, graffiti, 

  

	 	•	 	land vehicle crashes, 

  

	 	•	 	crashes of aircraft and space crafts, 

  

	 	•	 	crossing of sound through walls, 

  

	 	•	 	smoke, 

  

	 	•	 	natural disasters. 

 16.2- The Lessee, for itself as well as for any occupants due to its actions, shall have coverage for the
financial consequences of civil liability that it may incur due to its activities, in particular with respect to neighbors and any third parties. 
 The
Lessee shall ensure its own property, equipment and all objects in the LEASED PREMISES and any improvements and installations it has made, specifically against risks of fire and explosions. It shall take responsibility for its operating losses and
loss of enjoyment. 
 The Lessee shall obtain insurance against glass breakage and any real property damage resulting from thefts or attempted thefts. 

16.3 - The Lessee for itself as well as for any occupants due to its actions, waives and shall have its insurers waive any recourse against the Lessor and its
insurers for any tangible and intangible damage, including deprivation or disruption of enjoyment and operating losses, which may result from destruction or damage, in whole or in part, of the LEASED PREMISES due to fire, explosion and water damage.

 Reciprocally, the Lessor for itself as well as for any occupants due to its actions, waives and shall have its insurers waive any recourse against the
Lessee and its insurers for any tangible and intangible damage, including deprivation or disruption of enjoyment and operating losses, which may result from destruction or damage, in whole or in part, of the LEASED PREMISES due to fire, explosion
and water damage. The Lessor waives and shall have its insurers waive any recourse they may be entitled to bring against the Lessee, its insurers and any occupants due to its actions legally authorized for all tangible and intangible damage which
may result from fire, explosion and special risks which occurred in the building of which the leased premises are a part. 
 16.4 - The Lessee shall
maintain and renew its insurance for the entire term of the LEASE and provide proof upon the first request by the Lessor. The policies obtained shall be with companies that are known to be solvent which have a domicile in France. 

The Lessee shall be obligated to inform Lessor by registered letter with acknowledgment of delivery in the event of suspension or termination of their
contracts, regardless of the cause. 
 16.5 - The Lessee shall transmit to its insurers any information about its activities in the LEASED PREMISES which
may cause any change of the risk and premium rate. For this purpose, the Lessee shall be obligated to allow free access to the insurers of the lessor to enable them to properly evaluate the risks to be covered. 

16.6 - The Lessee shall repay to the Lessor all insurance premiums accounts including all taxes contracted by the Lessor for the building of which the LEASED
PREMISES are a part, on a prorated basis of the general fractions for dividing expenses or, if there are none, of the surface areas. The Lessee shall repay to interested parties, the Lessor, co-tenants or neighbors, any increases of premiums that
may result from its activities. 
 16.7 - The Lessee and its insurers waive any recourse in liability against the Lessor and its insurers for any damage
caused in the LEASED PREMISES, such damage must be considered by the insurance companies. 
 In particular, the Lessee specifically shall not claim that the
Lessor is liable: 
  

	 	•	 	in case of theft, burglary or any other act of which the Lessee might be a victim in the LEASED PREMISES or in the building of which the LEASED PREMISES are a part, 

 

	 	•	 	in the event of interruption of building services unless they are directly due to the fault, negligence or lack of care of the Lessor, 

 

	 	•	 	in the event of damage caused to the LEASED PREMISES, to equipment and objects there, as a consequence of floods, leakage, infiltration, moisture or another causes unless they are directly due to the fault, negligence
or lack of care of the Lessor, 

  

	 	•	 	in the event of accident which occurred in the LEASED PREMISES or in the building, 

	 	•	 	in the event of actions engaging the liabilities of the neighbors, of their staff, suppliers or customers, 

  

	 	•	 	in the event of illegal occupation of the building or LEASED PREMISES by third parties, 

  

	 	•	 	in the event of expropriation due to public utility. 

 16.8 - The Lessee shall be obligated to report in the
agreed time periods to its insurance company any accidents that occurred in the LEASED PREMISES. It shall send a copy of its report to the Lessor by the same letter. 

17) END OF LEASE – RETURN OF THE PREMISES 

17.1 - For the six months period preceding the end of the lease, the Lessor may have any potential buyer or tenant visit the leased premises, during business
hours. During the same period, the Lessor shall be entitled to post outside of the leased premises any signs and posters that it deems necessary to advertise the sale or lease. 

17.2 – Prior to any relocation, even partial of furniture and equipment, the Lessee shall provide proof, by submitting receipts of payment of all
contributions for which it is responsible for which the Lessor may be liable for any reason. The Lessee also must have paid all rents, expenses and related fees. 

17.3 - The leased premises shall be returned to the Lessor by the Lessee empty of any occupation and no later than the expiration date of the lease, in
perfect condition of any lease repairs, maintenance and compliance. For this reason, the Lessee expressly waives the right to rely on wear and tear and/or obsolescence within the meaning of Article 1755 of the Civil Code. 

The Lessee shall deliver to the Lessor at its expense and no later than the expiration date of the Lease, a certification of compliance of the electrical and
fire control installations signed by an approved organization. 
 Three months before the end of the lease, the Lessor may request, at the shared expense of
the Parties, the preparation of a pre-report of the conditions of the premises in the presence of both parties indicating any repairs, cleaning, restoration, replacement, painting work, restoration of floor coverings, that the Lessee may carry out
at its expense before the leased premises are returned, without prejudice to any other work that is shown only after the report of the condition of the premises when the Lessee leaves the premises. 

A report on the condition of the premises shall be prepared at the expense of the Lessee, amicably and in the presence of both Parties, or by a third party
authorized by them after the Lessee has completely moved out, either on the expiration date of the lease, or on the closest date possible. 
 If there is no
report on the condition of the premises, amicable and in the presence of both parties, it shall be prepared by a court bailiff, at the initiative of the most diligent party, and the costs shall be shared equally between the Lessor and the Lessee.

 The report on the condition of the premises when the Lessee leaves the premises shall be kept by each Party. The evaluation of the obligations of the
Lessee to repair the leased premises within the meaning of this article is done by comparison with the report at the beginning of the lease of the condition of the premises prepared no later than the effective date of the lease, including in the
case that the Lease was subject to one or more assignments or transfers during the Lease with preparation of a report on the condition of the premises on the date of the assignment or transfer of the lease. 

In any case, the keys shall be delivered no later than the expiration date of the lease. 

The Lessor may be represented at the report on the condition of the premises and/or pre-report on the condition of the premises, by its manager or by a
specialized company or any other person of its choice. 
 17.4 – In the event that repairs or restoration which are the responsibility of the Lessee
were not completed before the expiration of the lease, the Lessee shall no longer have access to the leased premises and the Lessor shall have prepared by the companies and the project manager of its choice, estimates for cleaning, remaking,
repairs, replacement, painting work and restoration made necessary in view of the findings that appear on the pre-report of the condition of the premises and/or the report on the condition of the premises when the Lessee leaves. The Lessee shall
then be liable to the Lessor, whether such work or restoration is performed by the Lessor or not, for the amount of such estimates, for the professional fees of the project manager and for compensation for the unavailability of the premises,
calculated on the same basis as the final rent, during any period necessary to complete the work, increased by fifteen days to request and obtain estimates. 

 The preparation of the pre-report on the condition of the premises within the meaning of Article 17.3 does not
constitute any mandatory obligation of the Lessor, which is free to have or not to have it prepared and its absence does not exonerate the Lessee in any way from its obligation to repair the leased premises within the meaning of this article. 

18) AMENDMENTS - TOLERANCE - INDIVISIBILITY 
 18.1
- The Lease shall be amended only by an amendment signed by the Parties or by exchanges of letters. 
 18.2 - No amendment may be inferred, either from the
passivity of the Lessor, or from simple tolerance, regardless of the frequency or duration, the Lessor remaining free to require the strict application of the lease and its endorsements at any time. 

18.3 - The lease is declared indivisible for the sole benefit of the Lessor in the event of any authorized sublease. 

18.4 - The Lessee shall be obligated to give notice to the Lessor within one month of any significant changes in its civil status or of the bylaws of its
company (change of name, transfer of registered office, change of form, etc.). The same shall apply in the case of provisional administration, any safeguard proceeding, placement in court-ordered restructuring, court-ordered liquidation or early
dissolution, but in such case, the period shall be reduced to eight days and the set off of the security deposit with any sums that may be owed by the Lessee shall be immediate and shall be done without formality. The Lease shall not continue with
immediate re-establishment of the contractual guarantees. 
 19) TERMINATION CLAUSE 

19.1 - It is expressly agreed that if there is no payment of a single installment or term fraction of the rent, charges and related fees, upon its due date, in
the case of non-performance of a single condition of the lease, three months after notice is given by extrajudicial instrument which remained ineffective, the lease shall be automatically terminated, if the Lessor deems it appropriate, even in the
case of payment or performance after the expiration of the above period. If the Lessee refuses to leave the premises, it shall be sufficient to force it to leave by a simple injunction, enforceable by provision and without notice. 

19.2 - The Lessee shall, in addition, be liable to the Lessor for all costs and professional fees before and during the dispute (specifically including costs
and professional fees of attorneys and court bailiffs, costs of experts) resulting from its delayed payment of any amount due under the lease or resulting from non-performance or failure to comply with any of the clauses of the lease, which shall be
added to any damages that the Lessor may claim from the Lessee. 
 19.3 - In the event of termination by acquisition of the termination clause, the rents
and charges paid in advance and the amount of the security deposit shall be kept by the Lessor, without it constituting a waiver by the Lessor of the right to obtain compensation in court for all of its injury. 

20) – OCCUPANCY COMPENSATION 
 If the leased
premises are not returned after termination of the lease or after contractual expiration of the lease, the Lessee shall be indebted to the Lessor, an occupancy payment set, by day of delay, at
1/360th of the last annual rent increased by a lump sum of 20% and by the VAT at the rate in effect until the date when the leased premises are returned, in addition to charges and taxes. 

21) - DESTRUCTION OF THE LEASED PREMISES 
 If the
leased premises are completely destroyed (explosion, fire in particular) the lease would be automatically cancelled without compensation to either Party. 

In the event of partial destruction of the leased premises, each Party shall be able to terminate the lease in accordance with article 1722 of the Civil Code.

 If the lease is not terminated following partial destruction of the leased premises, the Lessor and the Lessee
shall agree to calculate the amount of the reduction in rent corresponding to the destroyed surface area. 
 In the absence of an agreement, the most
diligent party shall refer the matter the court of competent jurisdiction within the meaning of Article 23.4. 
 22) - LEASE RENEWAL 

It is expressly agreed between the Parties that if the lease is renewed, it shall be renewed for one whole and consecutive 9 year period, with fixing of the
rent of the lease renewed according to the rental value within the meaning of the Article L. 145-33 of the Commercial Code. 
 23) - EXPENSES -
ELECTION OF DOMICILE 
 23.1 - The expenses, fees and professional fees of this lease, and those which shall be the result or the consequence, are
the responsibility of the Lessee, which agrees to be responsible, subject to the penalty of the termination clause. 
 23.2 - The Lessor elects domicile at
its Registered Office. 
 23.3 - The Lessee elects domicile at the leased premises. 

23.4 - For any disputes relating to the performance, interpretation or validity of this lease, the court is the court of the leased premises. 

Done in PARIS, in 2 originals, one for each Party. 
  

					
	On 06/9/2015	 		 	
	  
 LESSEE
	 		 	LESSOR
	  
 /s/ Gil Beyen
	 		 	/s/ [illegible]
			
		 		 	PFO2
		 		 	9 rue Jadin – 75017 PARIS
		 		 	Tel. 01 56 43 11 51 – Fax 01 56 43 11 49
		 		 	E-mail: [illegible] – www.perial.com
		 		 	[illegible] 638

 

 

 

 

 

 

 

 

 

 

			
	ERYTECH PHARMA	  	Version 06/03/2015
		  	  

PfO2

	  
 ADENINE
	  	
		
	60, avenue Rockefeller – 69008 LYON	  	

  

									
	 NATURE OF CHARGES
	  	Lessor	 	  	Lessee	 
	 Taxes and fees
	  				  			
	 real estate tax and additional taxes including recording fees
	  				  	 	100	% 
	 fee for household garbage removal including recording fees
	  				  	 	100	% 
	 sweeping fee
	  				  	 	100	% 
	 annual fee on offices
	  				  	 	100	% 
	 annual fee on commercial space
	  				  	 	100	% 
	 annual fee on storage space
	  				  	 	100	% 
	 fee on interior and exterior parking spaces
	  				  	 	100	% 
	 taxes, fees and user fees related to use of premise leased directly
	  				  	 	100	% 
	 taxes, fees and user fees related to services received by the Lessee
	  				  	 	100	% 
	 VAT on charges, rebilled fees, rents and occupancy payments
	  				  	 	100	% 
			
	 Maintenance Contracts, [illegible]
	  	 	 	  	 	 
	 guard service
	  				  	 	100	% 
	 access control – digital code
	  				  	 	100	% 
	 intercom
	  				  	 	100	% 
	 video monitoring
	  				  	 	100	% 
	 cleaning and maintenance of common areas
	  				  	 	100	% 
	 glass cleaning
	  				  	 	100	% 
	 cleaning of facades
	  				  	 	100	% 
	 sanitation and household supplies
	  				  	 	100	% 
	 rat extermination/disinfection/insect extermination/snow removal
	  				  	 	100	% 
	 maintenance of green spaces
	  				  	 	100	% 
	 replacement and planting of plants
	  				  	 	100	% 
	 maintenance and repair of exterior and interior parking areas
	  				  	 	100	% 
	 maintenance and restoration of courtyards and roadways
	  				  	 	100	% 
	 maintenance and restoration of paint, coating of floors and ceilings of common areas
	  				  	 	100	% 
	 maintenance and repair of air conditioning and heating systems
	  				  			
	 maintenance and partial restoration of roofs
	  				  	 	100	% 
	 maintenance and repair of lifts
	  				  	 	100	% 
	 maintenance and repair of doors and windows, including locks
	  				  	 	100	% 
	 maintenance and repair of automatic doors (pedestrian doors, gateways, parking area
doors)
	  				  	 	100	% 
	 maintenance and repair of plumbing in common areas
	  				  	 	100	% 
	 maintenance and repair of fire safety systems of the building (RIA, extinguishers, BAES, dry
columns, smoke removal)
	  				  	 	100	% 
	 inspection and repair of electrical installations in common areas
	  				  	 	100	% 
	 office operations mandatory periodic inspections
	  				  	 	100	% 
	 waste removal
	  				  	 	100	% 
	 renting of dumpsters and supplies of bags and containers
	  				  	 	100	% 
	 maintenance and repair of different systems (waste water, rain water)
	  				  	 	100	% 
	 multi-technical contracts
	  				  	 	100	% 
	 maintenance and repair of VMCs
	  				  	 	100	% 
	 maintenance and repair of lifting pumps
	  				  	 	100	% 
		  				  	 	100	% 
		  				  	 	100	% 

									
	 maintenance, repair and modernization of lifting devices (elevators, freight elevators, car
elevators)
	  				 	 	100	% 
	 leasing, readings and maintenance of sub-meters
	  				 			
	 maintenance, repair and replacement of lighting in common areas
	  				 	 	100	% 
	 salaries, social security contributions, related employee contributions
	  				 	 	100	% 
			
	 Fluids and Service Contracts
	  				 			
	 electricity
	  				 	 	100	% 
	 hot water
	  				 	 	100	% 
	 cold water
	  				 	 	100	% 
	 ice water
	  				 	 	100	% 
	 fuels
	  				 	 	100	% 
	 telephone service contracts
	  				 	 	100	% 
	 gas
	  				 			
	 fuel
	  				 	 	100	% 
			
	 Other Expenses
	  				 			
	 professional fees of the agent or agents – technical management
	  				 	 	100	% 
	 professional fees of the trustee
	  				 	 	100	% 
	 co-tenancy expenses
	  				 	 	100	% 
	 [illegible]
	  				 	 	[illegible	] 
	 miscellaneous maintenance and repairs
	  				 	 	100	% 
	 emergency guard services
	  				 	 	100	% 
	 bringing the building into compliance excluding construction work related to Article 606 of the
Civil Code
	  				 	 	100	% 
	 bringing the leased premises into compliance excluding construction work related to Article 606 of
the Civil Code
	  				 			
	 building insurance
	  				 	 	100	% 
	 reception services
	  				 			
	 costs and professional fees of disputes
	  				 	 	100	% 
	 report on condition of the premises excluding court bailiff
	  				 	 	100	% 
	 report on condition of the premises with court bailiff
	  				 	 	100	% 
	 salaries, social security contributions, related employee contributions
	  				 	 	100	% 
		  	 	50	% 	 	 	50	% 
		  				 	 	100	% 
			
	 Construction Work
	  				 			
	 bringing the building into compliance under Article 606 of the Civil Code
	  	 	100	% 	 			
	 bringing the leased premises into compliance under Article 606 of the Civil Code
	  	 	100	% 	 			
	 construction work intended to remedy obsolescence and under Article 606 of the Civil Code
	  	 	100	% 	 			
	 construction work intended to remedy obsolescence and not under Article 606 of the Civil
Code
	  				 	 	100	% 
	 restoration of facade without taking up masonry
	  				 	 	100	% 
	 restoration of facade with taking up masonry
	  	 	100	% 	 			
	 equipment repair
	  				 	 	100	% 
	 construction work and repairs related to Article 605 of the Civil Code
	  				 	 	100	% 
	 construction work and repairs related to Article 606 of the Civil Code
	  	 	100	% 	 			
	 professional fees for construction work related to Article 605 of the Civil Code
	  				 	 	100	% 
	 professional fees for construction work related to Article 606 of the Civil Code
	  	 	100	% 	 			

  

			
	DONE IN PARIS, IN TWO COPIES, ONE FOR EACH PARTY
	  
 On 06/09/2015
	 	
	  
 LESSEE
	 	LESSOR
	  
 /s/ Gil Beyen
	 	  
 /s/ [illegible]

 PfO2 

CONSTRUCTION WORK – 60 avenue Rockefeller – ADENINE – 69008 LYON 

 

																	
	 Description
	  	Status	 	  	Date	 	  	Amount excl. taxes	 	  	Charged to	 
	 modification of Totem of signage – waiting for SERL approval
	  	 	draft	 	  	 	2015	 	  	€	4,895.00	 	  	 	tenants	 
	 installing a ladder for glass cleaning
	  	 	draft	 	  	 	2015	 	  	€	3,318.70	 	  	 	tenants	 
	 installation of electric power meters
	  	 	draft	 	  	 	2016	 	  	€	6,763.75	 	  	 	tenants	 
	 installation of a general meter of cooling system on production
	  	 	draft	 	  	 	2016	 	  	€	15,063.50	 	  	 	tenants	 
		  				  				  	€	30,040.95	 	  			

 

 
 (Order of 6.8.05: Art. 16; Law of 7.13.06: Art. 79-IV; Law of 12.30.06; Decree of 9.5.06; Decree of 9.14.06;
Decree of 12.21.06) 
 (Art. 18 / CCH: Arr. L 271-4-I through L. 271-6) 

 

			
	è SUMMARY REPORT	  	MISSION NO. 361847

  

			
	OWNER	  	AGENT
		
	Name: not available	  	Name:
		
	Address: not available	  	Address
		
	City: not available	  	City:

  

					
	MISSION
		
	Address: 60 AVENUE ROCKFELLER	  	City: 69008 LYON
			
	Type:	  	No. of rooms:	  	
			
	Building:	  	Floor: not available	  	Doors:
		
	Building Reference: not available	  	Cadastral References: not available
		
	Principal Lots: not available	  	Secondary Lots: not available
			
	Tracking Date: 01/13/2015	  	Assistant: not available	  	
			
	Operator:	  		  	

  

			
	 Page 1 of 2
  

	 Tel.: 0 825 09 66 09
  

www.opera-groupe.fr – info@opera-groupe.fr
	 	 Corporate Headquarters: 37 rue d’Amsterdam, 75008 PARIS

 
 Management Office: 32 rue de la Part Dieu CS 83451,69421
LYON CEDEX 03

 

 
 MISSION NO. 361847 

è ☐ CERTIFICATION OF SURFACE AREA CARREZ LAW/LIVING AREA 

Not requested by person who placed order 
 è ☐ RECORD OF LEAD EXPOSURE RISKS – CREP 
 Not requested by person who placed order 

è ☐ REPORT MENTIONING THE PRESENCE OR ABSENCE OF MATERIALS OR PRODUCTS CONTAINING ASBESTOS 

Not requested by person who placed order 
 è ☐ REPORT RELATED TO PRESENCE OF TERMITES 
 Not requested by person who placed order 

è ☐ REPORT ON INTERIOR GAS INSTALLATION 

Not requested by person who placed order 
 è ☐ REPORT ON INTERIOR ELECTRICITY INSTALLATION 
 Not requested by person who placed order 

è ☒ REPORT ON NATURAL AND TECHNOLOGICAL RISKS 

ERNT 
 è ☐
ENERGY PERFORMANCE DIAGNOSIS 
 Not requested by person who placed order 
  

			
	 Page 2 of 2
  

	 Tel.: 0 825 09 66 09
  

www.opera-groupe.fr – info@opera-groupe.fr
	 	 Corporate Headquarters: 37 rue d’Amsterdam, 75008 PARIS

 
 Management Office: 32 rue de la Part Dieu CS 83451,69421
LYON CEDEX 03

					
	

	  		  	Report of Natural, Mining and Technological risks
		  		  	  
 in application of Articles L 125-5 and R 125-26 of the Environmental
Code

 1. This report, with respect to obligations, prohibitions, servitudes and
requirements set forth with respect to natural, mining or technological risks concerning the building, is prepared based on information provided by prefectural decision. 
  

							
		  	no.2011-1942	  	of 04/21/2011	  	updated on

 information with respect to the real property (built or not built)

  

											
	2. Address	  		  		 		  	Municipality      	  	
						
		  	postal code	  	69008	 	            	  		  	
						
	        60 AVENUE ROCKFELLER-ADENINE BUILDING	  	or insee code	  	69123	 		  	LYON	  	

 3. Siting of the building in view of one or more plans for prevention of natural risks (PPR n) 

											
						
	The building is located in the perimeter of a natural PPR	  	prescribed	  		  	yes ☐	  		  	no ☒
						
	The building is located in the perimeter of a natural PPR	  	applied in advance	  	            	  	yes ☐	  	        	  	no ☒
						
	The building is located in the perimeter of a natural PPR	  	approved	  		  	yes ☐	  		  	no ☒
						
	if yes, The natural risks taken into account are related to:	  		  		  		  		  	

  

											
	flooding ☐	 	torrential flooding ☐	 	landslides ☐	 				 	avalanches ☐
					
	drought ☐	 	cyclone ☐	 	rising of water table ☐	 				 	forest fire ☐
	    	 		 		 				 	
	earthquake ☐	 	volcano ☐	 	others  	 	 	

  

															
	extracts of reference documents attached to this report and allowing the location of the building in view of the risks considered
	
	Mapping of Natural Risks – Mapping of Seismic Risks
				
	The building is affected by construction work prescriptions in the regulation of the natural PPR or PPRs	  	yes ☐	  		  	no ☒
	if yes, the work prescribed by the regulation of the natural PPR or PPRs has been completed	  	yes ☐	  		  	no ☐
	
	4. Siting of the building in view of a plan to prevent mining risks (PPR m) in application of Article L 174-5 of the Mining Code.
						
	The building is located in the perimeter of a mining PPR	  	prescribed	  		  	yes ☐	  		  	no ☒
						
	The building is located in the perimeter of a mining PPR	  	applied in advance	  		  	yes ☐	  		  	no ☒
						
	The building is located in the perimeter of a mining PPR	  	approved	  	            	  	yes ☐	  	        	  	no ☒

															
	    	  		  				  		  		  		  	
		  	landslides ☐	  	 
	
                  
        others

	  		  		  	
		  		  				  		  		  		  	
	extracts of reference documents attached to this report and allowing the building to be located in view of risks considered
	    	  		  				  		  		  		  	
	The building is affected by work prescriptions in the PPR mining regulation	  	yes ☐  	  		  	no ☒
	if yes, the work prescribed by the PPR mining regulations has been completed	  	yes ☐  	  	        
	  	no ☐
	
	5. Siting of the building in view of a technological risks prevention plan (PPR t)
				
	 The building is located in the perimeter of a study of a technological PPR prescribed and not yet
approved
	  	yes ☐  	  		  	no ☒
	 if yes, the technological risks considered in the prescription decision are related
to

						
	                                    
toxic effect ☐	  	 	thermal effect ☐	 	  	Overpressure effect ☐	  		  		  	
	 The building is located in the perimeter of exposure to risks of an approved technological PPR
extracts of reference documents attached to this report and allowing the building to be located in view of risks considered
	  
	  	yes ☐	  	no ☒  	  		  	

  
  

											
	    
	 The building is affected by prescriptions on construction in the technological PPR regulation
	 	yes ☐	 	        	 	no ☒	 	
	 if yes, the work prescribed by the technological PPR has been completed
	 		 		 	yes ☐        	 	no ☐

  

											
	6. Siting of the building in view of regulatory zoning for consideration of seismicity
	
	  in application of Articles R 56304 and D 563-8-1 of the Environmental Code

											
						
		 	high	 	      average	 	      moderate	 	      low	 	    very low
						
	  The building is located in a seismicity commune	 	zone 5 ☐	 	      zone 4 ☐	 	      zone 3 ☐	 	      zone 2 ☒	 	    zone 1 ☐
	
	 7. Information with respect to losses compensated by insurance after a natural, mining or technological disaster

 
   in application of Article L 125-5 (IV) of the Environmental Code

													
						
	  The information is mentioned in the authentic instrument showing that the sale was completed seller/lessor – purchaser/tenant	 	yes ☐	 		 	no ☐        	 		 	

  

											
	8. Seller-Lessor first name	 		 	 PFO2
  
	 		 	  

	strike out inapplicable entry	 		 	Last Name	 		 	First Name	 	
	    	 		 		 		 		 	
						
	9. Purchaser – Tenant	 		 	  
	 		 	  
	 	
	  
 10. Date
	 	in  	 	 LYON
  
	 	        on  	 	01/14/2015                                	 	

  

Attention! If they do not involved any specific obligation or regulatory prohibition, known or foreseeable risks which might be indicated in the
various preventive informational documents and concerning the real property, the following are not mentioned by this report. Article 125-5 (V) of the Environmental Code: in event of failure to comply with obligations to inform the seller or
lessor, the purchaser or tenant may sue to terminate the contract or request that the court reduce the sale or lease price. 

  
 Page 1 of 1 

 

 

			
	

	  	 Information File for Purchasers and Tenants

 
 of Real Property, on Major Technological

 
 and Natural Risks

  
 

 

 list of natural disaster decisions (for information) 

			
		
	 Date of appearance of the decision in the OJ

(Official Journal)
	  	 Nature of Risk

	01/13/2008	  	Floods and mudslides
	10/14/2005	  	Earth movements
	02/09/2002	  	Floods by rising of water table
	08/23/2000	  	Floods and mudslides
	02/26/2000	  	Floods and mudslides
	07/09/1996	  	Floods and mudslides
	01/28/1996	  	Floods and mudslides
	08/03/1995	  	Floods and mudslides
	09/25/1994	  	Floods and mudslides
	06/25/1994	  	Floods and mudslides
	06/10/1994	  	Floods and mudslides
	02/18/1994	  	Floods and mudslides
	10/24/1993	  	Floods and mudslides
	12/15/1990	  	Floods and mudslides
	06/24/1983	  	Floods and mudslides
	06/24/1983	  	Floods and mudslides
	01/13/1983	  	Floods and mudslides
	01/29/1983	  	Snow Weight – Falling Snow
	12/22/1982	  	Snow Weight – Falling Snow
	11/19/1982	  	Storm

  
  

 

			
	 Date of preparation of this sheet
	  	02/13/2009

 GLOSSARY 

PPR: Risk Prevention Plan 
 They may concern
natural risks (PPRn) or technological risks (PPRt). 
  
  

 The risk prevention plan is a document prepared by the State which draws the boundaries of zones exposed to risks
and those not directly exposed in order to: 
  

	 	•	 	prohibit projects or prescribe conditions of construction and use in the plan, 

  

	 	•	 	define measures applicable to existing projects in the plan, 

  

	 	•	 	define preventive, protective and safeguard measures in the plan. 

 The different phases of carrying out the
PPR: 
 Prescription Decision (by the Prefect) 

It defines the risks to be considered and the scope of the PPR 

 PPR Project Established 

 

	•	 	of a presentation report which contains the analysis of the phenomena considered, and the study of their impact on persons and on property, existing and future. This report also indicates the principles for preparation
of the PPR and the discussion of the reasons for the regulation. 

  

	•	 	of a regulatory map at a scale between 1/10,000 and 1/5,000 generally, which draws the boundaries of the zones regulated by the PPR, 

 

	•	 	of a regulation which indicates the rules that apply to each zone. 

 Public Inquiry 

PPR Project possibly modified 

Approval Decision (by the Prefect) 

Annexing of the PPR to the Local Urban Development Plan or to the Land Occupancy Plan 

 Decision on Natural or Technological Disasters 

These are inter-ministerial decisions determining the zones and periods where disasters are located, and indicating the nature of the damage resulting from the
disasters. 
 They make it possible to know the risks incurred and have financial repercussions with respect to insurance deductibles if the commune does
not have a PPR. 
 Here are the applicable specific procedures, based on the number of findings of a state of natural disaster which occurred due to the
same risk during the five years prior to the date of any new finding: 
  

	 	•	 	1st and 2nd decisions of finding of natural disaster: application of the deductible; 

 

	 	•	 	At the 3rd decision: doubling of the applicable deductible; 

  

	 	•	 	At the 4th decision: tripling of the applicable deductible; 

  

	 	•	 	At the 5th decision and at following decisions: quadrupling of the applicable deductible. 

 

 
 FRENCH REPUBLIC 
  

			
	DEPARTMENTAL EQUIPMENT	  	PREFECTURE OF THE RHÔNE
		
	DIRECTORATE	  	

 PREFECTORAL DECISION No. 2009-3943 AMENDING PREFECTORAL DECISION 

No. 2006-1585 OF FEBRUARY 14 2006 AMENDED RELATED TO 

THE PROVISION OF INFORMATION TO PURCHASERS AND TENANTS 

OF REAL ESTATE ON MAJOR NATURAL AND TECHNOLOGICAL RISKS 

AND ACCIDENTS 
 IN THE
MUNICIPALITY OF LYON 
 PREFECT OF THE RHÔNE -ALPES REGION 

PREFECT OF THE RHÔNE 

CHEVALIER OF THE LEGION D’HONNEUR 

[KNIGHT OF THE LEGION OF HONOR] 
 IN VIEW OF the
General Code of Territorial Collectivities; 
 IN VIEW OF the Environmental Code, specifically Articles L 125-5 and R 125-23 through R 125-27; 

IN VIEW OF Decree No. 91-461 of May 14, 1991 amended related to the prevention of seismic risk; 

IN VIEW of prefectural decision no. 2009-3942 of July 20, 2009 amending prefectural decision no. 2006-1527 of February 14, 2006 amended related to
provision of information to purchasers and tenants of real estate on major natural and technological risks; 
 ON THE PROPOSAL by the Departmental
Director of Equipment; 
 DECISION 
 Article
1  
 In application of the provisions of Article 2 of Decision No. 2006-1585 of February 14, 2006 and as a result of the approval of the
natural flood risks prevention plan on the territory of the municipalities of Greater Lyon exposed to direct and indirect overflows of the Rhône and of the Saône in the Lyon and Villeurbanne sector, the information package of the
municipalities attached to this Decision No. 2006-1585 of February 14, 006, 

 
which contains elements necessary to prepare the risks report, intended for information on major natural and technological risks of real estate purchasers and tenants located in the Lyon
municipality is replaced by the package attached to this decision. 

 Article 2 

Ladies and Gentlemen, the secretary general of the prefecture of the Rhône, sub-prefects of districts, the departmental director of equipment and the
mayor of Lyon are responsible, each for the matters that concern him or her, for the application of this decision which shall be published in the compilation of administrative acts of the Rhône prefecture. 

Done in Lyon, on July 20, 2009 

Prefect 

 

 
 FRENCH REPUBLIC 

PREFECT OF THE RHÔNE 

PREFECTORAL DECISION No.2011-1942 AMENDING PREFECTORAL DECISION 

No.2009-3943 OF JULY 20, 2009 RELATED TO 

THE PROVISION OF INFORMATION TO PURCHASERS AND TENANTS 

OF REAL ESTATE ON MAJOR NATURAL AND TECHNOLOGICAL RISKS 

AND ACCIDENTS 
 IN THE
MUNICIPALITY OF LYON 
 PREFECT OF THE RHÔNE -ALPES REGION 

PREFECT OF THE RHÔNE 
 In view of the
General Code of Territorial Collectivities; 
 In view of the Environmental Code, specifically Articles L 125-5 and R 125-23 through R 125-27; 

In view of Decree No. 2010-1254 of October 22, 2010 related to the prevention of seismic risk; 

In view of Decree No. 2010-1255 of October 22, 2010 related to the setting of boundaries of seismicity zones on French territory; 

In view of prefectural decision no. 2011-2152 of April 26, 2011 amending prefectural decision no. 2010-6147 of November 26, 2010 related to
provision of information to purchasers and tenants of real estate on major natural and technological risks; 
 On the proposal of the Departmental Director
of Territories; 
 DECISION 
 Article 1

 As a result of the setting of boundaries in a zone of low seismicity of the municipality by the above-mentioned decree, the information package of the
commune attached to Decision No. 2009-3943 of July 20, 2009, which contains the elements necessary to prepare the risk report, intended for information on major natural and technological risks of real estate purchasers and tenants located
in the Lyon municipality, is supplemented by the information attached to this decision. 
 Article 2 

Ladies and Gentlemen, the secretary general of the prefecture of the Rhône, sub-prefects of districts, the departmental director of equipment and the
mayor of Lyon are responsible, each for the matters that concern him or her, for the application of this decision which shall be published in the compilation of administrative acts of the Rhône prefecture. 

 

					
		  	Done in Lyon, on April 26, 2011	  	 [stamp:] [For the Prefect,

General Secretary
  

Josiane CHEVALIER Prefect
  

[signature]

 Decisions on recognition of Natural Disaster 

Lyon 
 INSEE: 69123 – Population: 472,300 

Department: RHONE – Region: Rhône-Alpes 
 Update:
06/12/2012 
  

									
	Disaster Type	  	Start on	  	End on	  	Decision of	  	In OJ of
					
	Storm	  	11/06/1982	  	11/10/1982	  	11/18/1982	  	11/19/1982
					
	[illegible]	  	11/26/1982	  	11/27/1982	  	01/24/1983	  	01/29/1983
					
	Snow weight – Falling Snow	  	[illegible]	  	[illegible]	  	[illegible]	  	[illegible]
					
	Floods and mudslides	  	12/08/1982	  	12/31/1982	  	01/11/1983	  	01/13/1983
					
	Floods and mudslides	  	04/01/1983	  	04/30/1983	  	06/21/1983	  	06/24/1983
					
	Floods and mudslides	  	05/16/1983	  	05/18/1983	  	06/21/1983	  	06/24/1983
					
	Floods and mudslides	  	07/29/1990	  	07/29/1990	  	12/04/1990	  	12/15/1990
					
	Floods and mudslides	  	10/05/1993	  	10/10/1993	  	10/19/1993	  	10/24/1993
					
	Floods and mudslides	  	10/05/1993	  	10/10/1993	  	02/02/1994	  	02/18/1994
					
	Floods and mudslides	  	10/05/1993	  	10/10/1993	  	06/17/1996	  	07/09/1996
					
	Floods and mudslides	  	10/10/1993	  	10/10/1993	  	07/18/1995	  	08/03/1995
					
	Floods and mudslides	  	10/18/1993	  	10/18/1993	  	05/27/1994	  	06/10/1994
					
	Floods and mudslides	  	01/07/1994	  	01/21/1994	  	06/06/1994	  	06/25/1994
					
	Floods and mudslides	  	01/07/1994	  	01/21/1994	  	06/09/1994	  	06/09/1994
					
	Floods and mudslides	  	09/07/1995	  	09/07/1995	  	01/08/1996	  	01/28/1996
					
	Floods and mudslides	  	10/22/1999	  	10/24/1999	  	02/07/2000	  	02/26/2000
					
	Floods and mudslides	  	06/10/2000	  	06/10/2000	  	08/03/2000	  	08/23/2000
					
	Floods by raising of water table	  	03/18/2001	  	03/28/2001	  	01/23/2002	  	02/09/2002
					
	Landslides	  	04/17/2005	  	04/18/2005	  	10/06/2005	  	10/14/2005
					
	Floods and mudslides	  	08/06/2007	  	08/06/2007	  	01/10/2008	  	01/13/2008

 Ministry of Sustainable Development 

			
		
	Prefecture of: RHONE	  	 Declaration
 of compensated
claims

	
	in application of IV of Article L 125-5 of the Environmental Code
		
		  	 Building Address
  

		
		  	    
	 Municipality    

LYON    
	  	
		  	 Claims compensated in the framework

of recognition of the state of disaster

	 Decisions recognizing the state of    

disasters in favor of the municipality    
	  	 Check the YES or NO boxes

if, to your knowledge, the building was subject to

compensation
 [illegible]

events

  

											
	Storm	  	Decision dated 11/18/1982	  	☐ Yes	  		  	☐ No	  	
						
	Snow Weight – snowfall	  	Decision dated 12/15/1982	  	☐ Yes	  		  	☐ No	  	
						
	Floods and mudslides	  	Decision dated 01/11/1983	  	☐ Yes	  		  	☐ No	  	
						
	Snow Weight – snowfall	  	Decision dated 01/24/1983	  	☐ Yes	  		  	☐ No	  	
						
	Floods and mudslides	  	Decision dated 06/21/1983	  	☐ Yes	  		  	☐ No	  	
						
	Floods and mudslides	  	Decision dated 12/04/1990	  	☐ Yes	  		  	☐ No	  	
						
	Floods and mudslides	  	Decision dated 10/19/1993	  	☐ Yes	  		  	☐ No	  	
						
	Floods and mudslides	  	Decision dated 02/02/1994	  	☐ Yes	  		  	☐ No	  	
						
	Floods and mudslides	  	Decision dated 05/27/1994	  	☐ Yes	  		  	☐ No	  	
						
	Floods and mudslides	  	Decision dated 06/06/1994	  	☐ Yes	  		  	☐ No	  	
						
	Floods and mudslides	  	Decision dated 09/08/1994	  	☐ Yes	  		  	☐ No	  	
						
	Floods and mudslides	  	Decision dated 07/18/1995	  	☐ Yes	  	        	  	☐ No	  	        
						
	Floods and mudslides	  	Decision dated 01/08/1996	  	☐ Yes	  		  	☐ No	  	
						
	Floods and mudslides	  	Decision dated 06/17/1996	  	☐ Yes	  		  	☐ No	  	
						
	Floods and mudslides	  	Decision dated 02/07/2000	  	☐ Yes	  		  	☐ No	  	
						
	Floods and mudslides	  	Decision dated 08/03/2000	  	☐ Yes	  		  	☐ No	  	
						
	Floods by rising of water table	  	Decision dated 01/23/2002	  	☐ Yes	  		  	☐ No	  	
						
	Landslides	  	Decision dated 10/06/2005	  	☐ Yes	  		  	☐ No	  	
						
	Floods and mudslides	  	Decision dated 01/10/2008	  	☐ Yes	  		  	☐ No	  	

  

									
	                                      
                                  	 	Prepared on:  	 	                        	 	    	  	  

		 		 		 		  	Name and signature of seller or lessor
		 		 	    	 		  	
		 		 		 		  	     

	Stamp/Signature in case of service provider or	 		  	Signature of purchaser or tenant

 agent

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00275-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00275-of-00352.parquet"}]]