Document:

Exhibit
10.5

 

Intellectual
Property License Agreement

 

This
Intellectual Property License Agreement (this “Agreement”) is entered into as of June 28, 2021 (“Effective
Date”) between Bloom INVO LLC, a Delaware limited liability company (“Licensor” or “Company”),
and INVO Bioscience, Inc., a Nevada corporation (together with its Affiliates, “Licensee”). All defined terms used
herein appear in Article 9.

 

Whereas,
Licensor is in the business of providing management services to medical providers, including Bloom Fertility, LLC (“Provider”),
that offer treatments for patients seeking to overcome infertility, including by utilizing technologies originally developed by Licensee;
and

 

Whereas,
in connection with Licensor’s business, and the business of the medical providers that it manages, including Provider, it is anticipated
that Licensor (and/or one or more of its/their employees, agents, subcontractors, partners, officers, directors, interns and staff) may
create, generate, derive, develop or conceive, or otherwise obtain rights (including by assignment from the Provider) in improvements,
information and technology related to infertility, including the Developed IP; and

 

Whereas,
Licensor desires to grant to Licensee and its subsidiaries an exclusive, except as to Licensor, license to the Developed IP, effective
as of the earliest date effective and allowable under applicable law, under the terms and conditions set forth in this Agreement;

 

Now,
Therefore, in exchange for good and valuable consideration,
the receipt and sufficiency of which is hereby acknowledged, and incorporating the foregoing recitals, the parties agree as follows:

 

1.
License; Assignment and Ownership

 

1.1
License Grant. Subject to the terms and conditions of this Agreement, Licensor hereby grants to Licensee and its subsidiaries,
as of the Effective Date, an exclusive, except as to Licensor and Provider, royalty-free, perpetual, irrevocable, sublicensable (through
multiple tiers), right and license to make, use, import, sell, offer for sale, have sold, and otherwise Commercialize all Developments
and Company IP in any field in the Territory (collectively, the “License”).

 

(a)
Trademark Quality Control.

 

(i)
Licensee shall not, and shall ensure that its sublicensee(s) shall not, reproduce or use any Trademarks licensed under Section 1.1 (“Licensed
Trademarks”) in any manner whatsoever that does not materially comply with any reasonable trademark guidelines that Licensor
may provide from time to time.

 

(ii)
Licensee shall conduct its business, and shall ensure that its sublicensee(s) shall conduct their businesses, in a manner that will reflect
positively on the Licensed Trademarks. Licensee shall use, and shall ensure that its sublicensee(s) shall use, the Licensed Trademarks
in a manner that does not derogate Licensor’s rights in the Licensed Trademarks or the value of the Licensed Trademarks, and shall
take no action that would interfere with, diminish or tarnish those rights or value.

 

(iii)
Licensor will have the right to monitor Licensee’s and Licensee’s sublicensee(s)’ use of the Licensed Trademarks. Upon
Licensor’s reasonable request, but no more frequently than once per year, Licensee shall, and shall ensure that its sublicensee(s)
shall, submit to Licensor copies of any materials bearing the Licensed Trademarks. If Licensor discovers any improper use of the Licensed
Trademarks on any such submission and delivers a writing describing in detail the improper use to Licensee within seven (7) days after
receiving such submission, Licensee shall, and shall ensure that its sublicensee(s) shall, promptly remedy such improper use.

 

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(b)
Reservation of Rights. Except for those licenses and rights expressly granted in this Agreement, no license or right is granted
by either party to the other party by implication, estoppel or otherwise. Without limiting the generality of the foregoing and for the
avoidance of doubt, to the extent either party should wish to extend its rights beyond those rights as set forth in Article 1, such party
shall first seek the express written consent of the other party for such extension, which consent such other party may grant or deny
in its sole discretion.

 

1.2
Ownership of Company IP. Licensor shall retain exclusive ownership of the Company IP. Nothing in this Agreement transfers the
underlying ownership rights of such Company IP to Licensee. All use of the Licensed Trademarks by Licensee and its sublicensee(s), and
all goodwill associated with such use, shall inure to the sole benefit of Licensor. Licensor shall be required to file, maintain and
otherwise prosecute or litigate the protection of any Company IP.

 

2.
IP Protection

 

2.1
Enforcement. Licensor shall have the right (but not the obligation), in its sole discretion, to enforce the Company IP during
the Term of this Agreement.

 

2.2
Prosecution and Maintenance. Licensor shall take commercially reasonable efforts to protect and maintain the Company IP. Licensor
shall not abandon any Company IP that was registered as of the Effective Date, without first providing prior written notice to Licensee
and offering to transfer and assign to Licensee all right, title and interest in and to such IP, subject to Licensee agreeing to any
costs or fees associated with such IP.

 

3.
Confidential Information

 

3.1
Confidential Information. Each party agrees to maintain all Confidential Information of the other party in confidence to
the same extent that it protects its own similar Confidential Information, but not less than reasonable care, and to use such Confidential
Information of the other party only as permitted under this Agreement. Each party agrees to take reasonable precautions to prevent any
unauthorized disclosure or use of Confidential Information of the other party, including, without limitation, by disclosing such Confidential
Information only to its employees, contractors, agents, or Licensee’s sublicensee(s): (a) with a need to know such information,
(b) who are parties to appropriate agreements or confidentiality obligations sufficient to comply with this Section 3.1. In each case
of a disclosure of Confidential Information from one Party to the other, the receiving Party will take appropriate steps to implement
and enforce such non-disclosure/non-use obligations. The parties acknowledge and agree that Licensor may be required to file all or a
portion of this Agreement and make filings with respect to it with the SEC, and such disclosure will not be deemed a violation of Licensor’s
obligations hereunder.

 

3.2
Exclusions. The foregoing restrictions on disclosure and use will not apply with respect to any Confidential Information which:
(a) was or becomes publicly known through no fault of the receiving party; (b) was rightfully known or becomes rightfully known to the
receiving party without confidential or proprietary restriction from a source other than the disclosing party; (c) is documented by the
receiving party as having been independently developed by the receiving party without the participation of individuals who have had access
to the Confidential Information; (d) is approved by the disclosing party for disclosure without restriction in a written document signed
by a duly authorized officer of such disclosing party; and (e) the receiving party is legally compelled to disclose, provided, however,
prior to any such compelled disclosure, the receiving party will (i) assert the privileged and confidential nature of the Confidential
Information against the third Person seeking disclosure and (ii) reasonably cooperate with the disclosing party in allowing the disclosing
party to protect against any such disclosure and/or obtain a protective order narrowing the scope of such disclosure and/or use of the
Confidential Information. In the event that such protection against disclosure is not obtained, the receiving party will be entitled
to disclose the Confidential Information, but only as and to the extent reasonably necessary to legally comply with such compelled disclosure.
Each party agrees that the terms and conditions of this Agreement will be treated as Confidential Information of the other party, provided
that each party may disclose the terms and conditions of this Agreement: (1) as required by the applicable securities laws or (2) in
confidence, to legal counsel, accountants, banks and financing sources and their advisors, and in connection with the enforcement of
this Agreement or any rights hereunder.

 

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4.
Licensor’s Representations and Warranties; Disclaimer.

 

Licensor
represents and warrants to Licensee that Licensor has full corporate power and authority to enter into this Agreement and to carry out
its obligations hereunder. The execution and delivery by Licensor of this Agreement and the performance by Licensor of its obligations
hereunder have been duly authorized by all requisite corporate or stockholder action on the part of Licensor. This Agreement has been
duly executed and delivered by Licensor, and this Agreement constitutes a legal, valid and binding obligation of Licensor enforceable
against Licensor in accordance with its terms, except to the extent that enforcement of the rights and remedies created thereby is subject
to bankruptcy, insolvency, reorganization, moratorium and other similar laws of general application affecting the rights and remedies
of creditors and to general principles of equity (regardless of whether enforceability is considered in a proceeding in equity or at
law). EXCEPT FOR THE REPRESENTATIONS AND WARRANTIES EXPRESSLY SET FORTH HEREIN, LICENSOR MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY
KIND WHATSOEVER TO THE OTHER PARTY OR ANY OTHER ENTITY.

 

5.
Licensee’s Representations and Warranties; Disclaimers.

 

Licensee
has full corporate power and authority to enter into this Agreement and to carry out its obligations hereunder. The execution and delivery
by Licensee of this Agreement and the performance of its obligations hereunder have been duly authorized by all requisite corporate or
stockholder action on the part of such party. This Agreement has been duly executed and delivered by Licensee, and constitutes a legal,
valid and binding obligation of Licensee enforceable against it in accordance with its terms, except to the extent that enforcement of
the rights and remedies created thereby is subject to bankruptcy, insolvency, reorganization, moratorium and other similar laws of general
application affecting the rights and remedies of creditors and to general principles of equity (regardless of whether enforceability
is considered in a proceeding in equity or at law). EXCEPT FOR THE REPRESENTATIONS AND WARRANTIES EXPRESSLY SET FORTH IN THIS AGREEMENT,
LICENSEE MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND WHATSOEVER TO THE OTHER PARTY OR ANY OTHER ENTITY.

 

6.
Limitation of Liability

 

Each
party acknowledges and agrees that this Agreement represents the complete allocation of risks between the parties, it has voluntarily
accepted all risks assigned to it herein, and the disclaimer of warranties and limitation of remedies herein form an essential basis
of the bargain. TO THE EXTENT ALLOWED BY APPLICABLE LAW,
IN NO EVENT SHALL A PARTY BE LIABLE TO THE OTHER PARTY OR ANY OTHER PERSON FOR CONSEQUENTIAL, INCIDENTAL, SPECIAL, EXEMPLARY, PUNITIVE,
OR INDIRECT DAMAGES ARISING UNDER OR RELATED TO THIS AGREEMENT (INCLUDING LOST PROFITS, LOSS OF BUSINESS OR DATA, BUSINESS INTERRUPTION)
EVEN IF SUCH PARTY HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES OR LOSSES.

 

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7.
Term and Termination

 

7.1
Term; Termination. This Agreement will commence on the Effective Date and continue in perpetuity, unless terminated by
the written agreement of all parties to this Agreement, or unless terminated earlier in accordance with the terms hereof (the “Term”).
Either party shall have the right to terminate this Agreement if the other party is in material breach of any material term or condition
of this Agreement and fails to cure such breach within one hundred eighty (180) days after receipt of written notice of such breach given
by the non-breaching party.

 

7.2
Obligations Upon Termination. Upon termination of this Agreement, each party shall return to the other party any Confidential
Information received hereunder for which the party’s rights do not survive, or destroy or purge its own system and files of any
such Confidential Information (to the extent practicable) and deliver to the other party a written certificate signed by an officer of
such party that such destruction and purging have been carried out; provided, however, that the receiving party may retain copies that
are automatically retained as part of a computer back-up, recovery or similar archival or disaster recovery system, subject to the terms
of this Agreement.

 

7.3
Survival. Articles 3-5, 6-8, and 9 shall survive termination or expiration of the Agreement.

 

8.
General Provisions

 

8.1
Notices. Any notice, request, demand or other communication required or permitted hereunder will be in writing and deemed to be
properly given upon the earlier of (a) the date of transmission when sent by electronic mail, return receipt requested during normal
business hours; or (b) five (5) business days after deposit when mailed by certified mail, return receipt requested, or two (2) business
days after being sent via private industry courier to the respective parties at the addresses set forth on the signature page hereto,
which may be amended by a party upon five (5) days’ notice to the other party.

 

8.2
Assignment. Neither Party shall assign this Agreement, nor any of its rights or obligations hereunder, to any other Person without
the prior written consent of the other Party, which shall not be unreasonably withheld.

 

8.3
Governing Law. This Agreement is to be construed in accordance with and governed by the internal laws of the State of Delaware
(“State”) without giving effect to any choice or conflict of law provision or rule (whether of the State or any other
jurisdiction). Any legal suit, action or proceeding arising out of or relating to this Agreement will be commenced in federal court in
the State, and each party hereto irrevocably submits to the exclusive jurisdiction and venue of any such court in any such suit, action
or proceeding.

 

8.4
Waiver. The waiver by any party of a breach of or a default under any provision of this Agreement will be in writing and will
not be construed as a waiver of any subsequent breach of or default under the same or any other provision of the Agreement, nor will
any delay or omission on the part of a party to exercise or avail itself of any right or remedy that it has or may have hereunder operate
as a waiver of any right or remedy.

 

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8.5
Severability. If the application of any provision or provisions of this Agreement to any particular facts or circumstances is
held to be invalid or unenforceable by any court of competent jurisdiction, then (a) the validity and enforceability of such provision
or provisions as applied to any other particular facts or circumstances and the validity of other provisions of this Agreement will not
in any way be affected or impaired thereby, and (b) such provision or provisions will be reformed without further action by the parties
hereto and only to the extent necessary to make such provision or provisions valid and enforceable when applied to such particular facts
and circumstances.

 

8.6
Relationship of the Parties. This Agreement, in and of itself, will not be construed as creating an agency, partnership, joint
venture or any other form of association, for tax purposes or otherwise, between the parties.

 

8.7
Construction. This Agreement shall be construed as if jointly drafted by the parties hereto and no rule of construction or strict
interpretation shall be applied against either party. The titles to Articles and headings of Sections contained in this Agreement, in
any Schedule and in the table of contents to this Agreement have been inserted for convenience of reference only and shall not be deemed
to be a part of or to affect the meaning or interpretation of this Agreement.

 

8.8
Counterparts. This Agreement may be executed in one or more counterparts, each of which will be deemed to be an original, and
which together will constitute one Agreement.

 

8.9
Entire Agreement. This Agreement constitutes the entire agreement between the parties concerning the subject matter hereof and
supersedes all prior negotiations, conditions, agreements, or communications between them relating to the subject matter hereof. No amendment
or modification of any provision of this Agreement will be effective unless in writing and signed by the Parties.

 

9.
Definitions

 

Capitalized
terms used in this Agreement will have the following meanings:

 

9.1
“Affiliate” as to a party means (i) any entity controlled by, controlling or under common control with that party
now or in the future (control shall be deemed to mean having a right to 50% of the entity’s profits or ownership of at least 50%
of the voting rights in the entity), or (ii) any entity in which Licensee, now or in the future, holds an interest.

 

9.2
“Clinical Trial” means a human clinical study conducted on sufficient numbers of human subjects that is designed to
(a) establish that a pharmaceutical product or medical device is reasonably safe for continued testing; (b) investigate the safety and
efficacy of the pharmaceutical product or medical device for its intended use, and to define warnings, precautions and adverse reactions
that may be associated with the pharmaceutical product in the dosage range to be prescribed or the medical device; or (c) support regulatory
approval of such pharmaceutical product or medical device or Label expansion of such pharmaceutical product or medical device.

 

9.3
“Company IP” means all IP now or hereafter owned by Licensor, including but not limited to the Developed IP.

 

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9.4
“Confidential Information” means any information and/or materials disclosed by one party to the other in written,
oral, graphic, electronic or other form that (a) is marked or identified in writing as confidential, proprietary, or with other marks
indicative of a confidential nature, (b) if disclosed orally or in other intangible form or in any form that is not so marked, is identified
as confidential (or other terms indicative of a confidential nature) at the time of such disclosure, or (c) includes, comprises or contains
financial information, proposals, prospects or customer lists, research, development, testing data, samples, parts, pricing, computer
programs (including source code), models, designs, unpublished patent applications, trade secrets, know-how, formulas, processes, flow
charts, techniques, ideas, inventions (whether patentable or not), schematics and other technical, business, financial and product development
plans, forecasts, strategies, systems, works of authorship, projects, any other business, marketing, financial, technical, scientific,
engineering, and other non-public information, or other information of the disclosing party that is disclosed in circumstances of confidence.

 

9.5
“Commercialization” means any and all activities of marketing, promoting, distributing, offering for sale or selling
the Product in the Field in the Territory, including, for example, marketing, branding, pricing, distribution, sales, obtaining health
insurance reimbursement coverage, market research, business analytics, pharmacovigilance and medical affairs activities (including conducting
post-marketing clinical studies), pre-commercial launch market development activities conducted in anticipation of regulatory approval
to sell or market the Product, seeking pricing and reimbursement approvals for the Product, preparing advertising and promotional materials,
sales force training, and all interactions and correspondence with a regulatory authority regarding post-regulatory approval Clinical
Trials. When used as a verb, “Commercialize” means to engage in Commercialization.

 

9.6
“Developments” means all information and technology related to Field, and any intellectual property arising therefrom,
that Licensor creates, generates, derives, develops or conceives, or otherwise obtains rights in, after the Effective Date.

 

9.7
“Developed IP” means any and all IP that has or may in the future arise from any Developments.

 

9.8
“Documentation” means with respect to the Company IP and any Developments, all documentation, including, but not limited
to, user manuals, data sheets, schematics, test and verification plans and reports, application notes, design documents, programming
guides, and other documents related to the Field and useful for Commercializing the Company IP and/or the Developments.

 

9.9
“Field” means all therapeutic, prophylactic and diagnostic uses of medical devices or pharmaceutical products involving
assisted reproductive technology (including infertility treatment) in humans.

 

9.10
“Governmental Authority” means any federal, state, local or foreign government or political subdivision thereof, or
any agency or instrumentality of such government or political subdivision, or any self-regulated organization or other non-governmental
regulatory authority or quasi-governmental authority (but only to the extent that the rules, regulations or orders of such organization
or authority have the force of law), or any arbitrator, court or tribunal of competent jurisdiction.

 

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9.11
“Intellectual Property” or “IP” means any and all of the following in any jurisdiction throughout
the world: (a) patents and patent applications, (including all related continuations, continuations-in-part, divisionals, reissues, reexaminations,
substitutions, renewals, extensions, nationalizations, validations, counterparts (domestic or foreign) or restorations of any of the
foregoing (regardless of lapse, expiration or abandonment status), and other Governmental Authority-issued indicia of invention ownership
(including certificates of invention, petty patents, and patent utility models) together with industrial designs, registrations, applications
for registration, and renewals thereof (“Patents”); (b) copyrights and works of authorship, whether or not copyrightable,
and all registrations, applications for registration, and renewals of, any of the foregoing, and mask works, and all registrations, applications
for registrations, and renewals thereof, including: computer aided design files including electrical schematics, bill of materials, layout
files, gerber files, mechanical CAD files, and artwork files (“Copyrights”); (c) trademarks, service marks, brands,
certification marks, logos, trade dress, trade names, and other similar indicia of source or origin, together with the goodwill connected
with the use of and symbolized by, and all registrations, applications for registration, and renewals of, any of the foregoing (“Trademarks”);
(d) trade secrets, know-how, inventions (whether or not patentable), discoveries, improvements, technology, business and technical information,
databases, data compilations and collections, tools, methods, processes, techniques, and other confidential and proprietary information
(“Know-How”) Software; and any other proprietary, intellectual or industrial property, including but not limited to
domain names (“Domain Names”).

 

9.12
“Label” means the approved display of written, printed or graphic matter either (a) on the immediate container, packaging
or wrapper of an article or (b) inside a container, package or wrapper so long as it is easily legible through the outside container
or wrapper.

 

9.13
“Person” means an individual, corporation, partnership, joint venture, limited liability company, Governmental Authority,
unincorporated organization, trust, association or other entity.

 

9.14
“Product” means any medical device or product related to fertility and/or the treatment of infertility in humans.

 

9.15
“Software” means any and all of the following: (i) computer programs and other software, including software implementations
of algorithms, models, and methodologies, whether in source code, object code, firmware or other form, including libraries, application
programming interfaces, subroutines and other components thereof; (ii) computerized databases and other computerized compilations and
collections of data or information, including all data and information included in such databases, compilations or collections; (iii)
screens, user interfaces, command structures, report formats, templates, menus, buttons and icons; (iv) descriptions, flow-charts, architectures,
development tools, specifications, protocols, and other materials used to design, plan, organize and develop any of the foregoing; (v)
all Documentation, including development, diagnostic, support, user and training documentation related to any of the foregoing; and (vi)
enhancements, updates, releases, upgrades, bug fixes, error corrections, patches, new versions, translations, conversions or other modifications
or additions, as applicable, to any of the foregoing.

 

9.16
“Territory” means worldwide.

 

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In
Witness Whereof, the parties have caused this Agreement
to be executed by duly authorized representatives of the parties as of the Effective Date.

 

	LICENSOR	 	LICENSEE
	 	 	 
	Bloom
    INVO LLC, a Delaware limited liability company	 	INVO
    Bioscience, Inc., a Nevada corporation
	 	 	 
	By:	/s/
    Sue Ellen Carpenter	 	By:	/s/
    Steven Shum
	 	Signature

    
	 	 	Signature
	 	 	 	 	 
	Name:	Sue
    Ellen Carpenter, M.D.	 	Name:	Steven
    Shum
	Title:	Chief
    Executive Officer	 	Title:	Chief
    Executive Officer
	 	 	 	 	 
	Address:
    

Bloom INVO LLC

 5582 Broadcast Court 

Sarasota, Florida 34240 

Email: legal@invobio.com	 	Address:
    

INVO Bioscience, Inc. 

5582 Broadcast Court 

Sarasota, Florida 342240 

Email: legal@invobio.com

 

    	8Exhibit
10.6

 

Intellectual
Property License Agreement

 

This
Intellectual Property License Agreement (this “Agreement”) is entered into as of June 28, 2021 (“Effective
Date”) between INVO Bioscience, Inc., a Nevada corporation, and Bio X Cell, Inc., a Massachusetts corporation (each a “Licensor”
and together, “Licensors”), and Bloom INVO LLC, a Delaware limited liability company (“Licensee”).
All defined terms used herein appear in Article 9.

 

Whereas,
Licensors are medical device companies focused on developing and creating simplified, lower cost treatments for patients diagnosed with
infertility; and

 

Whereas,
Licensors have pioneered, tested, created and developed proprietary intravaginal culture medical devices (“INVOcell”),
in vivo methods of vaginal incubation (“INVO Procedures”), and other related treatments and technologies to
enhance reproductive success (together with the INVOcell and INVO Procedures, the “INVO Technologies”); and

 

Whereas,
Licensors are, individually or collectively, the owners of certain IP related to the INVO Technologies, including the INVO IP, and desire
to grant to Licensee a license to the INVO IP, under the terms and conditions set forth in this Agreement, in connection with the establishment
of one or more INVO Clinics operating in the Field and in the Territory;

 

Now,
Therefore, in exchange for good and valuable consideration,
the receipt and sufficiency of which is hereby acknowledged, and incorporating the foregoing recitals, the parties agree as follows:

 

1.
License

 

1.1
License Grant and Retention of Rights. Subject to the terms and conditions of this Agreement, Licensors (individually and collectively)
hereby grant to Licensee, as of the Effective Date, a non-exclusive, royalty-free, perpetual, sublicensable (through multiple tiers),
right and license to make, use, import, sell, offer for sale, have sold, and otherwise Commercialize the INVO IP in the Field in the
Territory (collectively, the “License”).

 

1.2
Trademark Quality Control.

 

(a)
Licensee shall not, and shall ensure that its sublicensee(s) shall not, reproduce or use any Trademarks licensed under Section 1.1
(“Licensed Trademarks”) in any manner whatsoever other than as expressly authorized by this Agreement, and all
uses of the Licensed Trademarks will materially comply with any reasonable trademark guidelines that Licensors may provide from time
to time.

 

(b)
Licensee shall conduct its business, and shall ensure that its sublicensee(s) shall conduct their businesses, in a manner that will reflect
positively on the Licensed Trademarks. Licensee shall use, and shall ensure that its sublicensee(s) shall use, the Licensed Trademarks
in a manner that does not derogate Licensors’ respective rights in the Licensed Trademarks or the value of the Licensed Trademarks,
and shall take no action that would interfere with, diminish or tarnish those rights or value. All Products that bear the Licensed Trademarks
shall be of a quality at least as great as the quality of Licensors’ INVOcell prior to the Effective Date.

 

(c)
Licensee will not use, and shall ensure that its sublicensee(s) shall not use, any Trademark confusingly similar to any of the Licensed
Trademarks, without both Licensors’ consent. Licensee agrees, and shall ensure that its sublicensee(s) agree, not to register or
attempt to register any Licensed Trademarks or any Trademark confusingly similar to any of the Licensed Trademarks, without both Licensors’
consent.

 

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(d)
Licensors will have the right to monitor Licensee’s and Licensee’s sublicensee(s)’ use of the Licensed Trademarks.
Upon either Licensors’ reasonable request, but no more frequently than once per year collectively, Licensee shall, and shall ensure
that its sublicensee(s) shall, submit to either or both Licensors copies of any materials bearing the Licensed Trademarks. If either
or both Licensors discover any improper use of the Licensed Trademarks on any such submission and delivers a writing describing in detail
the improper use to Licensee within seven (7) days after receiving such submission, Licensee shall, and shall ensure that its sublicensee(s)
shall, promptly remedy such improper use.

 

1.3
Reservation of Rights. Except for those licenses and rights expressly granted in this Agreement, no license or right is granted
by either party to the other party by implication, estoppel or otherwise. Without limiting the generality of the foregoing and for the
avoidance of doubt, to the extent either party should wish to extend its rights beyond those rights as set forth in this Article 1, such
party shall first seek the express written consent of the other party for such extension, which consent such other party may grant or
deny in its sole discretion.

 

1.4
Ownership of INVO IP. Licensors shall retain their respective exclusive ownership of the INVO IP. Nothing in this Agreement transfers
any ownership rights of such INVO IP. All use of any Licensed Trademarks by Licensee and its sublicensee(s), and all goodwill associated
with such use, shall inure to the sole benefit of the Licensor that owns the respective Licensed Trademark. Except as expressly set forth
in this agreement, Licensors shall not be required to file, maintain or otherwise prosecute or litigate the protection of any INVO IP
other than in the sole and absolute discretion of Licensors. Licensee covenants and agrees, and shall ensure that its sublicensee(s)
covenant and agree, not to challenge or assist any Person in challenging the validity, enforceability or other viability of any INVO
IP.

 

2.
IP Protection

 

2.1
Enforcement. Licensors shall have the right (but not the obligation), in its sole discretion, to enforce the INVO IP during the
Term of this Agreement. In the event that any of the INVO IP are infringed by a third Person in the Field and one or more of Licensors
institute an action or proceeding against such third Person to enforce the INVO IP, Licensee, at the sole cost and expense of Licensor,
shall cooperate with and provide assistance reasonably requested by such Licensor(s) in furtherance of such action or proceeding.

 

2.2
Prosecution and Maintenance. Licensors shall take commercially reasonable efforts to protect and maintain the INVO IP. Each Licensor’s
decision, which may be made in its sole discretion as to INVO IP for which it is the sole owner, to rely on unregistered forms of protection
instead of registered forms of protection shall in all cases be deemed to be commercially reasonable under this Agreement; provided,
however, that neither Licensor may abandon any INVO Registered IP for which such Licensor is the sole owner and which was registered
as of the Effective Date, without first providing prior written notice to Licensee and offering to transfer and assign to Licensee all
right, title and interest in and to such IP, subject to Licensee agreeing to any costs or fees associated with such IP, and subject to
a perpetual, royalty-free, sublicensable, unlimited, non-exclusive license from Licensee back to the Licensors under such IP.

 

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3.
Confidential Information

 

3.1
Confidential Information. Each party agrees to maintain all Confidential Information of the other party in confidence to
the same extent that it protects its own similar Confidential Information, but not less than reasonable care, and to use such Confidential
Information of the other party only as permitted under this Agreement. Each party agrees to take reasonable precautions to prevent any
unauthorized disclosure or use of Confidential Information of the other party, including, without limitation, by disclosing such Confidential
Information only to its employees, contractors, agents, or Licensee’s sublicensee(s): (a) with a need to know such information,
(b) who are parties to appropriate agreements or confidentiality obligations sufficient to comply with this Section 3.1. In each case
of a disclosure of Confidential Information from one Party to the other, the receiving Party will take appropriate steps to implement
and enforce such non-disclosure/non-use obligations. The parties acknowledge and agree that Licensor may be required to file all or a
portion of this Agreement and make filings with respect to it with the SEC, and such disclosure will not be deemed a violation of Licensor’s
obligations hereunder.

 

3.2
Exclusions. The foregoing restrictions on disclosure and use will not apply with respect to any Confidential Information which:
(a) was or becomes publicly known through no fault of the receiving party; (b) was rightfully known or becomes rightfully known to the
receiving party without confidential or proprietary restriction from a source other than the disclosing party; (c) is documented by the
receiving party as having been independently developed by the receiving party without the participation of individuals who have had access
to the Confidential Information; (d) is approved by the disclosing party for disclosure without restriction in a written document signed
by a duly authorized officer of such disclosing party; and (e) the receiving party is legally compelled to disclose, provided, however,
prior to any such compelled disclosure, the receiving party will (i) assert the privileged and confidential nature of the Confidential
Information against the third Person seeking disclosure and (ii) reasonably cooperate with the disclosing party in allowing the disclosing
party to protect against any such disclosure and/or obtain a protective order narrowing the scope of such disclosure and/or use of the
Confidential Information. In the event that such protection against disclosure is not obtained, the receiving party will be entitled
to disclose the Confidential Information, but only as and to the extent reasonably necessary to legally comply with such compelled disclosure.
Each party agrees that the terms and conditions of this Agreement will be treated as Confidential Information of the other party, provided
that each party may disclose the terms and conditions of this Agreement: (1) as required by the applicable securities laws or (2) in
confidence, to legal counsel, accountants, banks and financing sources and their advisors, and in connection with the enforcement of
this Agreement or any rights hereunder.

 

4.
Licensors’ Representations and Warranties; Disclaimer.

 

Licensors
represent and warrant to Licensee that Licensors have full corporate power and authority to enter into this Agreement and to carry out
their respective obligations hereunder. The execution and delivery by Licensors of this Agreement and the performance by Licensors of
their obligations hereunder have been duly authorized by all requisite corporate or stockholder action on the part of each Licensor.
This Agreement has been duly executed and delivered by Licensors, and constitutes a legal, valid and binding obligation of Licensors
enforceable against Licensors in accordance with its terms, except to the extent that enforcement of the rights and remedies created
thereby is subject to bankruptcy, insolvency, reorganization, moratorium and other similar laws of general application affecting the
rights and remedies of creditors and to general principles of equity (regardless of whether enforceability is considered in a proceeding
in equity or at law). EXCEPT FOR THE REPRESENTATIONS AND WARRANTIES EXPRESSLY SET FORTH HEREIN, LICENSORS MAKE NO FURTHER REPRESENTATIONS
OR WARRANTIES OF ANY KIND WHATSOEVER TO THE OTHER PARTY OR ANY OTHER ENTITY.

 

    	3

     

    

 

5.
Licensee Representations and Warranties; Disclaimers.

 

Licensee
has full corporate power and authority to enter into this Agreement and to carry out its obligations hereunder. The execution and delivery
by Licensee of this Agreement and the performance of its obligations hereunder have been duly authorized by all requisite company and
member action on the part of such party. This Agreement has been duly executed and delivered by Licensee, and constitutes a legal, valid
and binding obligation of Licensee enforceable against it in accordance with its terms, except to the extent that enforcement of the
rights and remedies created thereby is subject to bankruptcy, insolvency, reorganization, moratorium and other similar laws of general
application affecting the rights and remedies of creditors and to general principles of equity (regardless of whether enforceability
is considered in a proceeding in equity or at law). EXCEPT FOR THE REPRESENTATIONS AND WARRANTIES EXPRESSLY SET FORTH IN THIS AGREEMENT,
LICENSEE MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND WHATSOEVER TO THE OTHER PARTY OR ANY OTHER ENTITY.

 

6.
Limitation of Liability

 

Each
party acknowledges and agrees that this Agreement represents the complete allocation of risks between the parties, it has voluntarily
accepted all risks assigned to it herein, and the disclaimer of warranties and limitation of remedies herein form an essential basis
of the bargain. TO THE EXTENT ALLOWED BY APPLICABLE LAW,
IN NO EVENT SHALL A PARTY BE LIABLE TO THE OTHER PARTY OR ANY OTHER PERSON FOR CONSEQUENTIAL, INCIDENTAL, SPECIAL, EXEMPLARY, PUNITIVE,
OR INDIRECT DAMAGES ARISING UNDER OR RELATED TO THIS AGREEMENT (INCLUDING LOST PROFITS, LOSS OF BUSINESS OR DATA, BUSINESS INTERRUPTION)
EVEN IF SUCH PARTY HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES OR LOSSES.

 

7.
Term and Termination

 

7.1
Term; Termination. This Agreement will commence on the Effective Date and continue in perpetuity, unless terminated by
the written agreement of all parties to this Agreement, or unless terminated earlier in accordance with the terms hereof (the “Term”).
Either party shall have the right to terminate this Agreement if the other party is in material breach of any material term or condition
of this Agreement and fails to cure such breach within one hundred eighty (180) days after receipt of written notice of such breach given
by the non-breaching party.

 

7.2
Obligations Upon Termination. Upon termination of this Agreement, each party shall return to the other party any Confidential
Information received hereunder for which the party’s rights do not survive, or destroy or purge its own system and files of any
such Confidential Information (to the extent practicable) and deliver to the other party a written certificate signed by an officer of
such party that such destruction and purging have been carried out; provided, however, that the receiving party may retain copies that
are automatically retained as part of a computer back-up, recovery or similar archival or disaster recovery system, subject to the terms
of this Agreement.

 

7.3
Survival. Articles 3-5, 6-8, and 9 shall survive termination or expiration of the Agreement.

 

    	4

     

    

 

8.
General Provisions

 

8.1
Notices. Any notice, request, demand or other communication required or permitted hereunder will be in writing and deemed to be
properly given upon the earlier of (a) the date of transmission when sent by electronic mail, return receipt requested during normal
business hours; or (b) five (5) business days after deposit when mailed by certified mail, return receipt requested, or two (2) business
days after being sent via private industry courier to the respective parties at the addresses set forth on the signature page hereto,
which may be amended by a party upon five (5) days’ notice to the other party.

 

8.2
Assignment. Except as otherwise set forth herein with respect to sublicensees, Licensee shall not assign this Agreement, nor any
of its rights or obligations hereunder, to any other Person without the prior written consent of both Licensors, which may be withheld
for any reason in each Licensor’s sole discretion.

 

8.3
Governing Law. This Agreement is to be construed in accordance with and governed by the internal laws of the State of Delaware
(“State”) without giving effect to any choice or conflict of law provision or rule (whether of the State or any other
jurisdiction). Any legal suit, action or proceeding arising out of or relating to this Agreement will be commenced in federal court in
the State, and each party hereto irrevocably submits to the exclusive jurisdiction and venue of any such court in any such suit, action
or proceeding.

 

8.4
Waiver. The waiver by any party of a breach of or a default under any provision of this Agreement will be in writing and will
not be construed as a waiver of any subsequent breach of or default under the same or any other provision of the Agreement, nor will
any delay or omission on the part of a party to exercise or avail itself of any right or remedy that it has or may have hereunder operate
as a waiver of any right or remedy.

 

8.5
Severability. If the application of any provision or provisions of this Agreement to any particular facts or circumstances is
held to be invalid or unenforceable by any court of competent jurisdiction, then (a) the validity and enforceability of such provision
or provisions as applied to any other particular facts or circumstances and the validity of other provisions of this Agreement will not
in any way be affected or impaired thereby, and (b) such provision or provisions will be reformed without further action by the parties
hereto and only to the extent necessary to make such provision or provisions valid and enforceable when applied to such particular facts
and circumstances.

 

8.6
Relationship of the Parties. This Agreement, in and of itself, will not be construed as creating an agency, partnership, joint
venture or any other form of association, for tax purposes or otherwise, between the parties.

 

8.7
Construction. This Agreement shall be construed as if jointly drafted by the parties hereto and no rule of construction or strict
interpretation shall be applied against either party. The titles to Articles and headings of Sections contained in this Agreement, in
any Schedule and in the table of contents to this Agreement have been inserted for convenience of reference only and shall not be deemed
to be a part of or to affect the meaning or interpretation of this Agreement.

 

8.8
Counterparts. This Agreement may be executed in one or more counterparts, each of which will be deemed to be an original, and
which together will constitute one Agreement.

 

    	5

     

    

 

8.9
Entire Agreement. This Agreement constitutes the entire agreement between the parties concerning the subject matter hereof and
supersedes all prior negotiations, conditions, agreements, or communications between them relating to the subject matter hereof. No amendment
or modification of any provision of this Agreement will be effective unless in writing and signed by the Parties.

 

9.
Definitions

 

Capitalized
terms used in this Agreement will have the following meanings:

 

9.1
“Affiliate” as to a party means any entity controlled by, controlling or under common control with that party now
or in the future (control shall be deemed to mean having a right to 50% of the entity’s profits or ownership of at least 50% of
the voting rights in the entity).

 

9.2
“Clinical Trial” means a human clinical study conducted on sufficient numbers of human subjects that is designed to
(a) establish that a pharmaceutical product or medical device is reasonably safe for continued testing; (b) investigate the safety and
efficacy of the pharmaceutical product or medical device for its intended use, and to define warnings, precautions and adverse reactions
that may be associated with the pharmaceutical product in the dosage range to be prescribed or the medical device; or (c) support regulatory
approval of such pharmaceutical product or medical device or Label expansion of such pharmaceutical product or medical device.

 

9.3
“Confidential Information” means any information and/or materials disclosed by one party to the other in written,
oral, graphic, electronic or other form that (a) is marked or identified in writing as confidential, proprietary, or with other marks
indicative of a confidential nature, (b) if disclosed orally or in other intangible form or in any form that is not so marked, is identified
as confidential (or other terms indicative of a confidential nature) at the time of such disclosure, or (c) includes, comprises or contains
financial information, proposals, prospects or customer lists, research, development, testing data, samples, parts, pricing, computer
programs (including source code), models, designs, unpublished patent applications, trade secrets, Know-how, formulas, processes, flow
charts, techniques, ideas, inventions (whether patentable or not), schematics and other technical, business, financial and product development
plans, forecasts, strategies, systems, works of authorship, projects, any other business, marketing, financial, technical, scientific,
engineering, and other non-public information, or other information of the disclosing party that is disclosed in circumstances of confidence.

 

9.4
“Commercialization” means any and all activities of marketing, promoting, distributing, offering for sale or selling
the Product in the Field in the Territory, including, for example, marketing, branding, pricing, distribution, sales, obtaining health
insurance reimbursement coverage, market research, business analytics, pharmacovigilance and medical affairs activities (including conducting
post-marketing clinical studies), pre-commercial launch market development activities conducted in anticipation of regulatory approval
to sell or market the Product, seeking pricing and reimbursement approvals for the Product, preparing advertising and promotional materials,
sales force training, and all interactions and correspondence with a regulatory authority regarding post-regulatory approval Clinical
Trials. When used as a verb, “Commercialize” means to engage in Commercialization.

 

9.5
“Documentation” means with respect to the INVO Technologies, all documentation, including, but not limited to, user
manuals, data sheets, schematics, test and verification plans and reports, application notes, design documents, programming guides, and
other documents of either or both Licensors related to the technology useful to Commercialize the same.

 

    	6

     

    

 

9.6
“Ferring Agreement” means that certain Distribution Agreement by and among Ferring International Center S.A. and INVO
Bioscience, Inc., and BIO X Cell, Inc., dated November 12, 2018 (together with any current and future amendments thereto).

 

9.7
“Field” means the Commercialization of the INVO Technologies and the Product through an INVO Clinic in the Territory.

 

9.8
“Governmental Authority” means any federal, state, local or foreign government or political subdivision thereof, or
any agency or instrumentality of such government or political subdivision, or any self-regulated organization or other non-governmental
regulatory authority or quasi-governmental authority (but only to the extent that the rules, regulations or orders of such organization
or authority have the force of law), or any arbitrator, court or tribunal of competent jurisdiction.

 

9.9
“Intellectual Property” or “IP” means any and all of the following in any jurisdiction throughout
the world: (a) patents and patent applications, (including all related continuations, continuations-in-part, divisionals, reissues, reexaminations,
substitutions, renewals, extensions, nationalizations, validations, counterparts (domestic or foreign) or restorations of any of the
foregoing (regardless of lapse, expiration or abandonment status), and other Governmental Authority-issued indicia of invention ownership
(including certificates of invention, petty patents, and patent utility models) together with industrial designs, registrations, applications
for registration, and renewals thereof (“Patents”); (b) copyrights and works of authorship, whether or not copyrightable,
and all registrations, applications for registration, and renewals of, any of the foregoing, and mask works, and all registrations, applications
for registrations, and renewals thereof, including: computer aided design files including electrical schematics, bill of materials, layout
files, gerber files, mechanical CAD files, and artwork files (“Copyrights”); (c) trademarks, service marks, brands,
certification marks, logos, trade dress, trade names, and other similar indicia of source or origin, together with the goodwill connected
with the use of and symbolized by, and all registrations, applications for registration, and renewals of, any of the foregoing (“Trademarks”);
and (d) trade secrets, know-how, inventions (whether or not patentable), discoveries, improvements, technology, business and technical
information, databases, data compilations and collections, tools, methods, processes, techniques, and other confidential and proprietary
information (“Know-How”) Software.

 

9.10
“INVO Clinic” means any clinic, established in whole or in part by INVO Bioscience, Inc. (or an Affiliate thereof),
that exclusively Commercializes the INVO Technologies in the Territory in order to Commercialize the Product.

 

9.11
“INVO IP” means all IP owned by Licensors, individually or collectively, as of the Effective Date and throughout the
Term that relate to the INVO Technologies.

 

9.12
“INVO Registered IP” means all INVO IP that is subject to any issuance, registration, or application for registration
by or with any Governmental Authority or authorized private registrar in any jurisdiction, including those specifically identified in
Exhibit A.

 

9.13
“Label” means the approved display of written, printed or graphic matter either (a) on the immediate container, packaging
or wrapper of an article or (b) inside a container, package or wrapper so long as it is easily legible through the outside container
or wrapper.

 

9.14
“Person” means an individual, corporation, partnership, joint venture, limited liability company, Governmental Authority,
unincorporated organization, trust, association or other entity.

 

    	7

     

    

 

9.15
“Product” means INVO’s proprietary intravaginal culture device known as INVOcell, together with any applicable
accessories, including, without limitation, the retention device (each of which is more specifically described in Exhibit B), together
with all current and future formulations, versions, improvements, modifications and presentations of such product by Licensors and their
Affiliates from time to time.

 

9.16
“Software” means any and all of the following: (i) computer programs and other software, including software implementations
of algorithms, models, and methodologies, whether in source code, object code, firmware or other form, including libraries, application
programming interfaces, subroutines and other components thereof; (ii) computerized databases and other computerized compilations and
collections of data or information, including all data and information included in such databases, compilations or collections; (iii)
screens, user interfaces, command structures, report formats, templates, menus, buttons and icons; (iv) descriptions, flow-charts, architectures,
development tools, specifications, protocols, and other materials used to design, plan, organize and develop any of the foregoing; (v)
all Documentation, including development, diagnostic, support, user and training documentation related to any of the foregoing; and (vi)
enhancements, updates, releases, upgrades, bug fixes, error corrections, patches, new versions, translations, conversions or other modifications
or additions, as applicable, to any of the foregoing.

 

9.17
“Territory” means the State of Georgia.

 

[Signature
Page Follows]

 

    	8

     

    

 

In
Witness Whereof, the parties have caused this Agreement
to be executed by duly authorized representatives of the parties as of the Effective Date.

 

	LICENSORS	 	LICENSEE
	 	 	 
	INVO
    Bioscience, Inc., a Nevada corporation 	 	Bloom
    INVO LLC, a Delaware limited liability company
	 	 	 	 	 
	By:
    	/s/
    Steven Shum	 	By:
    	/s/Sue
    Ellen Carpenter
	Name:
    	Steven
    Shum	 	Name:
    	Sue
    Ellen Carpenter, M.D.
	Title:
    	Chief
    Executive Officer	 	Title:
    	Chief
    Executive Officer

 

	Address:

     

    INVO
    Bioscience, Inc.

    5582
    Broadcast Court

    Sarasota,
    Florida 34240

    Email:
    legal@invobio.com
	 	Address:

     

    Bloom
    INVO, LLC

    5582
    Broadcast Court

    Sarasota,
    Florida 34240

    Email:
    legal@invobio.com

 

	Bio
    X Cell, Inc. 	 
	 	 	 
	By:
    	 	 
	Name:
    	Steven
    Shum	 
	Title:
    	Treasurer
    and Secretary	 

 

	Address:

     

    Bio
    X Cell, Inc.

    5582
    Broadcast Court

    Sarasota,
    Florida 34240

    Email:
    legal@invobio.com
	 

 

    	9

     

    

 

Exhibit
A

 

Schedule
of INVO Registered IP

 

Patents
and Patent Applications

 

	No.	 	Title	 	Pat./Pub.
    No.	 	App.
    No.	 	Status	 	Jurisdiction
	1.	 	Incubation
    and/or storage container system and method	 	7,759,115	 	10/360,630	 	Active	 	US
	2.	 	Intravaginal
    culture incubation container and method	 	US
    2021-0145560	 	16/949,960	 	Pending	 	US
	3.	 	Improved
    Incubation and/or Storage Container System and Method	 	N/A	 	62/938,122	 	Expired	 	US
	4.	 	IVC
    Container and Method	 	N/A	 	62/938,154	 	Expired	 	US
	5.	 	Improved
    intravaginal culture incubation container and method	 	WO
    2021/102473	 	PCT/US2021/013798	 	Pending	 	PCT

 

Registered
Trademarks

 

	No.	 	Mark	 	Jurisdiction	 	Status	 	Holder	 	App.
    No.	 	Reg.
    No.	 	App.
    Date.
	1	 	INVO
    BIOSCIENCE	 	US	 	Active	 	INVO
    Bioscience, Inc.	 	77613704	 	4009828	 	11/13/2008
	2	 	INVOCELL	 	IS	 	Pending	 	INVO
    Bioscience, Inc.	 	V0118990	 	N/A	 	10/11/2020
	3	 	INVOCELL	 	IL	 	Pending	 	INVO
    Bioscience, Inc.	 	332248	 	N/A	 	8/5/2020
	4	 	INVOCELL	 	CA	 	Pending	 	INVO
    Bioscience, Inc.	 	2056336	 	N/A	 	8/5/2020
	5	 	INVOCELL	 	WO	 	Active	 	INVO
    Bioscience, Inc.	 	1553631	 	1553631	 	8/5/2020
	6	 	INVOBABY	 	US	 	Pending	 	INVO
    Bioscience, Inc.	 	88804749	 	N/A	 	2/20/2020
	7	 	INVOCELL	 	US	 	Active	 	INVO
    Bioscience, Inc.	 	88797622	 	6146631	 	2/14/2020
	8	 	INVOCELL	 	IS	 	Active	 	INVO
    Bioscience, Inc.	 	V0115473	 	V0115473	 	12/1/2019
	9	 	INVO	 	IS	 	Pending	 	INVO
    Bioscience, Inc.	 	V0115405	 	N/A	 	11/24/2019
	10	 	INVOcell	 	JO	 	Active	 	INVO
    Bioscience, Inc.	 	JOT1152758	 	169758	 	11/6/2019
	11	 	INVO	 	JO	 	Active	 	INVO
    Bioscience, Inc.	 	JOT1152757	 	169820	 	11/6/2019
	12	 	INVO	 	WO	 	Active	 	INVO
    Bioscience, Inc.	 	1499563	 	1499563	 	10/10/2019
	13	 	INVOCELL	 	WO	 	Active	 	INVO
    Bioscience, Inc.	 	1500083	 	1500083	 	10/10/2019
	14	 	INVO	 	IL	 	Active	 	INVO
    Bioscience, Inc.	 	322569	 	322569	 	10/10/2019
	15	 	INVOCELL	 	IL	 	Active	 	INVO
    Bioscience, Inc.	 	322763	 	322763	 	10/10/2019
	16	 	INVO	 	CA	 	Pending	 	INVO
    Bioscience, Inc.	 	1997132	 	N/A	 	10/10/2019
	17	 	INVOCELL	 	CA	 	Pending	 	INVO
    Bioscience, Inc.	 	1998355	 	N/A	 	10/10/2019
	18	 	INVO
    CENTER	 	US	 	Pending	 	INVO
    Bioscience, Inc.	 	88564596	 	N/A	 	8/2/2019
	19	 	INVO	 	US	 	Active	 	INVO
    Bioscience, Inc.	 	77613693	 	4009827	 	11/13/2008
	20	 	INVOCELL	 	US	 	Active	 	INVO
    Bioscience, Inc.	 	77180109	 	3757982	 	5/14/2007
	21	 	INVO	 	BR	 	Active	 	INVO
    Bioscience, Inc.	 	918229723	 	918229723	 	09/17/2019
	22	 	INVO	 	AR	 	Active	 	INVO
    Bioscience, Inc.	 	3844974	 	3155564	 	10/18/2019
	23	 	INVOCELL	 	BR	 	Active	 	INVO
    Bioscience, Inc.	 	918229790	 	918229790	 	09/17/2019
	24	 	INVOCELL	 	AR	 	Pending	 	INVO
    Bioscience, Inc.	 	3916439	 	N/A	 	07/22/2020
	25	 	INVOCELL	 	BR	 	Pending	 	INVO
    Bioscience, Inc.	 	501553631	 	N/A	 	08/05/2020
	26	 	INVOcell	 	AR	 	Pending	 	INVO
    Bioscience, Inc.	 	3844977	 	N/A	 	10/18/2019

 

Registered
Copyrights

 

None.

 

Domain
Names

 

None.

 

    	10

     

    

 

Exhibit
B

 

Product
Description

 

The
INVOcell is an Intravaginal Culture System. An intravaginal culture system is a prescription device intended for preparing, holding,
and transferring human gametes or embryos during intravaginal in vitro fertilization or intravaginal culture procedures.

 

The
INVOcell Culture Device (FG-003) is a two-part assembly enclosed in two separate packages. The first package contains the first part,
including the inner chamber coupled with a cap (see Figures 1-3). The second package contains the second part, including the top and
bottom parts of the outer vessel (see Figure 4).

 

The
inner chamber holds culture medium, eggs and sperm, or ICSI fertilized embryos. In an INVOcell procedure, the inner chamber is placed
into the outer vessel, which provides additional resistance to contamination. Following the loading of gametes or embryos, the INVOcell
Culture Device is assembled and placed in the vaginal cavity for 72 hours (3-days) to allow for embryo development.

 

FIGURE
1: INNER CHAMBER (contents of the first package)

 

 

With
the Cap off the Inner Chamber (5149-029-A) the entire center section is open to load the contents. See Figure 1, above. After the contents
are loaded, line up the tabs in the Cap (5149-030-A) with the slots on the top of the Inner Chamber (5149-029-A) and press the Cap (5149-030-A)
on as illustrated in Figure 2, below.

 

    	11

     

    

 

FIGURE
2: CAP AND INNER CHAMBER (contents of the first package)

 

 

With
the Cap (5149-030-A) pressed firmly onto the Inner Chamber (5149-029-A) the tabs will be aligned with the slots and the Cap can then
be rotated into a locked position, thereby securing the Cap to the Inner Chamber as shown below in Figure 3.

 

FIGURE
3: CAP COUPLED WITH INNER CHAMBER (contents of the first package)

 

 

    	12

     

    

 

FIGURE
4: OUTER RIGID SHELL FOR CELL CULTURE CONTAINER (contents of the second package)

 

 

In
addition to the outer vessel (referred to in Figure 4 as “outer rigid shell”), the INVOcell Intravaginal Culture System also
includes a Retention Device (P-017). The Retention Device is a single-use, medical grade silicone device that is similar in shape and
material to a diaphragm or menstrual cup. The Retention Device has holes to allow for natural drainage of vaginal fluids. The Retention
Device is placed into the vaginal cavity with the INVOcell Culture Device to ensure that the INVOcell Culture Device is retained in the
vaginal cavity for 72 hours (3-days). The retention device comes in 1 size: 70mm.

 

    	13

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