Document:

Form of Lock-Up Agreement, dated January 12, 2007

 Exhibit 4.3.3 
 LOCK-UP AGREEMENT 
 THIS LOCK-UP AGREEMENT (the “Agreement”) is made and entered
into on January 12, 2007 between the stockholder set forth on the signature page to this Agreement (the “Holder”) and Synova Healthcare Group, Inc. a Nevada corporation (the “Company”). 
 RECITALS 
 A. The Company has
determined that it is advisable and in its best interest to enter into that certain Securities Purchase Agreement, dated January 12, 2007 (the “Purchase Agreement”) with the Purchasers named therein (the
“Purchasers”), pursuant to which the Company will issue and sell in a private offering securities of the Company (the “Offering”). Capitalized terms used and not otherwise defined herein that are defined in the
Purchase Agreement will have the meanings given such terms in the Purchase Agreement. 
 B. In connection with the Offering, the Company has
agreed to provide the Purchasers certain registration rights, and in furtherance thereof has agreed to file a registration statement to enable the Purchasers to resell certain of the securities subject of the Offering. 
 C. It is a condition to the Purchasers’ respective obligations to close under the Purchase Agreement and provide the financing contemplating by the
Offering that each Holder execute and deliver to the Company this Agreement. 
 D. In contemplation of, and as a material inducement for the
Purchasers to enter into, the Purchase Agreement, the Holder and the Company have each agreed to execute and deliver this Agreement. 
 NOW,
THEREFORE, for and in consideration of the mutual covenants and agreements set forth herein, and other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the parties, intending to be legally bound, agree as
follows: 
 1. Effectiveness of Agreement. This Agreement shall become null and void if the Purchase Agreement is terminated prior to
closing. The Holder has independently evaluated the merits of its decision to enter into and deliver this Agreement, and such Holder confirms that it has not relied on the advice of the Company or any other person. 
 2. Representations and Warranties. Each of the parties hereto, by their respective execution and delivery of this Agreement, hereby represents and
warrants to the others and to all third party beneficiaries of this Agreement that (a) such party has the full right, capacity and authority to enter into, deliver and perform its respective obligations under this Agreement, (b) this
Agreement has been duly executed and delivered by such party and is the binding and enforceable obligation of such party, enforceable against such party in accordance with the terms of this Agreement and (c) the execution, delivery and
performance of such party’s obligations under this Agreement will not conflict with or breach the terms of any other agreement, contract, commitment or understanding to which such party is a party or to which the assets or securities of such
party are bound. 

 3. Beneficial Ownership. Holder hereby represents and warrants that it does not beneficially own
(as determined in accordance with Section 13(d) of the Exchange Act of 1934, as amended, and the rules and regulations promulgated thereunder) any shares of Common Stock, or any economic interest therein or derivative therefrom, other than
those shares of Common Stock specified on its signature page to this Agreement. For purposes of the Agreement the shares of Common Stock beneficially owned by such Holder as specified on its signature page to this Agreement are collectively referred
to as the “Holder’s Shares.” 
 4. Lockup. During the one-year period commencing on the date hereof (the
“Lockup Period”), the Holder irrevocably agrees it will not offer, pledge, sell, contract to sell, sell any option or contract to purchase, purchase any option or contract to sell, grant any option, right or warrant to purchase or
otherwise transfer or dispose of, directly or indirectly, or announce the offering of, any of Holder’s Shares (including any securities convertible into, or exchangeable for, or representing the rights to receive, Holder’s Shares), except
as otherwise provided in Section 3.2(g) of the Purchase Agreement. In furtherance thereof, the Company will (x) place a stop order on all Holder’s Shares covered by any registration statements, (y) notify its transfer agent in
writing of the stop order and the restrictions on such Holder’s Shares under this Agreement and direct the transfer agent not to process any attempts by the Holder to resell or transfer any Holder’s Shares under such registration
statements or otherwise in violation of this Agreement. 
 5. Third-Party Beneficiaries. The Holder and the Company acknowledge and
agree that this Agreement is entered into for the benefit of and is enforceable by the Purchasers and their successors and assigns. 
 6.
No Additional Fees/Payment. Other than the consideration specifically referenced herein, the parties hereto agree that no fee, payment or additional consideration in any form has been or will be paid to the Holder in connection with this
Agreement. 
 7. Enumeration and Headings. The enumeration and headings contained in this Agreement are for convenience of reference
only and shall not control or affect the meaning or construction of any of the provisions of this Agreement. 
 8. Counterparts. This
Agreement may be executed in facsimile and in any number of counterparts, each of which when so executed and delivered shall be deemed an original, but all of which shall together constitute one and the same agreement. 
 9. Successors and Assigns. This Agreement and the terms, covenants, provisions and conditions hereof shall be binding upon, and shall inure to the
benefit of, the respective heirs, successors and assigns of the parties hereto. 
 10. Severability. If any provision of this
Agreement is held to be invalid or unenforceable for any reason, such provision will be conformed to prevailing law rather than voided, if possible, in order to achieve the intent of the parties and, in any event, the remaining provisions of this
Agreement shall remain in full force and effect and shall be binding upon the parties hereto. 
  

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 11. Amendment. This Agreement may not be amended or modified in any manner except by a written
agreement executed by each of the parties hereto if and only if such modification or amendment is consented to in writing by the Purchasers holding a majority in interest of the Common Stock issued or issuable under the Purchase Agreement.

 12. Further Assurances. Each party shall do and perform, or cause to be done and performed, all such further acts and things, and
shall execute and deliver all such other agreements, certificates, instruments and documents, as any other party may reasonably request in order to carry out the intent and accomplish the purposes of this Agreement and the consummation of the
transactions contemplated hereby. 
 13. No Strict Construction. The language used in this Agreement will be deemed to be the language
chosen by the parties to express their mutual intent, and no rules of strict construction will be applied against any party. 
 14.
Remedies. The Company and the Purchasers shall have the right to specifically enforce all of the obligations of the Holder under this Agreement (without posting a bond or other security), in addition to recovering damages by reason of any
breach of any provision of this Agreement and to exercise all other rights granted by law. Furthermore, the Holder recognizes that if it fails to perform, observe, or discharge any of its obligations under this Agreement, any remedy at law may prove
to be inadequate relief to the Company or the Purchasers. Therefore, the Holder agrees that each of the Company and the Purchasers shall be entitled to seek temporary and permanent injunctive relief in any such case without the necessity of proving
actual damages and without posting a bond or other security. 
 15. Governing Law. The terms and provisions of this Agreement shall be
construed in accordance with the laws of the State of New York and the federal laws of the United States of America applicable therein. 
 [Remainder of Page Intentionally Left Blank] 
  

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 IN WITNESS WHEREOF, each of the parties hereto has caused this Agreement as of the day and year first
above written. 
  

					
	
	  
	Name:	 	
	
	Number of shares of Common Stock beneficially owned:
	
	  
	
	SYNOVA HEALTHCARE GROUP, INC.
		
	By:	 	  
		 	Name:	 	
		 	Title:	 	

 {Signature Page to Synova Healthcare Group, Inc. Lock-up Agreement} 

 

 4Form of Securities Purchase Agreement, dated January 12, 2007

 Exhibit 4.4 
 SECURITIES PURCHASE AGREEMENT 
 This Securities Purchase Agreement (this
“Agreement”) is dated as of January 12, 2007, among Synova Healthcare Group, Inc., a Nevada corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its
successors and assigns, a “Purchaser” and collectively the “Purchasers”). 
 WHEREAS, subject to the terms
and conditions set forth in this Agreement and pursuant to Section 4(2) of the Securities Act of 1933, as amended (the “Securities Act”) and Rule 506 promulgated thereunder, the Company desires to issue and sell to each
Purchaser, and each Purchaser, severally and not jointly, desires to purchase from the Company, securities of the Company as more fully described in this Agreement, which issuance and sale the Company determined to be an exempt issuance within the
meaning of its existing finance documents. 
 NOW, THEREFORE, IN CONSIDERATION of the mutual covenants contained in this Agreement, and for
other good and valuable consideration the receipt and adequacy of which are hereby acknowledged, the Company and each Purchaser agree as follows: 
 ARTICLE I. 
 DEFINITIONS 
 1.1 Definitions. In addition to the terms defined elsewhere in this Agreement, for all purposes of this Agreement, the following terms have the meanings indicated in this Section 1.1: 
 “Action” shall have the meaning ascribed to such term in Section 3.1(k). 
 “Affiliate” means any Person that, directly or indirectly through one or more intermediaries, controls or is controlled
by or is under common control with a Person as such terms are used in and construed under Rule 144 under the Securities Act. With respect to a Purchaser, any investment fund or managed account that is managed on a discretionary basis by the same
investment manager as such Purchaser will be deemed to be an Affiliate of such Purchaser. 
 “Allendale”
means Allendale Pharmaceuticals, Inc. 
 “Allendale Acquisition Agreement” means the agreement attached
hereto as Exhibit A hereto pursuant to which the Company shall acquire by merger all of the issued and outstanding capital stock of Allendale. 
 “Allendale Contracts” shall have the meaning ascribed to such term in Section 3.1(hh). 
 “Allendale Financial Statements” means the audited financial statements of Allendale at and for the years ending December 31, 2005 and December 31, 2004 and its unaudited financial
statements at and for the six month period ending June 30, 2006. 
 “Allendale Form 8-K” means the Form
8-K to be filed by the Company with the Commission to report the Company’s acquisition of all of the issued and outstanding 

 
capital stock of Allendale pursuant to Item 2.01 of Form 8-K and to include the financial statements and exhibits required at the date of this Agreement
by Item 9.01 of Form 8-K as a result of such acquisition. 
 “Allendale Securities” means the securities
of the Company issued and issuable under the Allendale Acquisition Agreement. 
 “Benefit Arrangement” means
at any time an employee benefit plan within the meaning of Section 3(3) of ERISA which is not a Plan or Multiemployer Plan and which is maintained or otherwise contributed by the Company. 
 “Benefit Plan” has the meaning set forth in Section 3.1(kk)(ii). 
 “Business Day” means any day except Saturday, Sunday, any day which shall be a federal legal holiday in the United States
or any day on which banking institutions in the State of New York are authorized or required by law or other governmental action to close. 
 “Closing” means the closing of the purchase and sale of the Notes and Warrants pursuant to Section 2.1. 
 “Closing Date” means the Trading Day when all of the Transaction Documents have been executed and delivered by the
applicable parties thereto, and all conditions precedent (i) under Section 2.2(b) to the Purchasers’ obligations to pay the Subscription Amount and (ii) under Section 2.2(a) to the Company’s obligations to deliver the
Notes and Warrants have been satisfied or waived. 
 “Closing Price” means on any particular date
(a) the last reported closing price per share of Common Stock on such date on a Trading Market (as reported by Bloomberg L.P. at 4:15 PM (New York time)), or (b) if there is no such price on such date, then the closing price on the Trading
Market on the date nearest preceding such date (as reported by Bloomberg L.P. at 4:15 PM (New York time)), or (c) if the Common Stock is not then listed or quoted on a Trading Market and if prices for the Common Stock are then quoted on the
Over the Counter Bulletin Board, then the last reported closing price per share of Common Stock on such date (or if none on such date, the preceding date) so reported, or (d) if the Common Stock is not then listed or quoted on the Trading
Market and if prices for the Common Stock are then reported in the “pink sheets” published by Pink Sheets LLC (or a similar organization or agency succeeding to its functions of reporting prices), the most recent bid price per share of the
Common Stock so reported, or (d) if the shares of Common Stock are not then publicly traded the fair market value of a share of Common Stock as determined by an appraiser selected in good faith by the Purchasers of a majority in interest of the
Shares then outstanding. 
 “Commission” means the Securities and Exchange Commission. 
 “Common Stock” means the common stock of the Company, par value $0.001 per share, and any other class of securities into
which such common stock may hereafter be reclassified or changed into. 
  

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 “Common Stock Equivalents” means any securities of the Company or the
Subsidiaries which entitle the holder thereof to acquire, directly or indirectly, at any time Common Stock, including, without limitation, any debt, preferred stock, rights, options, warrants or other instrument that is at any time convertible into
or exercisable or exchangeable for, or otherwise entitles the holder thereof to receive, Common Stock. 
 “Company
Counsel” means Blank Rome LLP. 
 “Contingent Liability” means, as to any Person, any obligation of
such Person guaranteeing or intended to guarantee any Indebtedness, leases, dividends or other obligations (“primary obligations”) of any other Person (the “primary obligor”) in any manner, whether directly or
indirectly, including any obligation of such Person, whether or not contingent, (i) to purchase any such primary obligation or any property constituting direct or indirect security therefor, (ii) to advance or supply funds (x) for the
purchase or payment of any such primary obligation or (y) to maintain working capital or equity capital of the primary obligor or otherwise to maintain the net worth or solvency of the primary obligor, (iii) to purchase property,
securities or services primarily for the purpose of assuring the owner of any such primary obligation of the ability of the primary obligor to make payment of such primary obligation or (iv) otherwise to assure or hold harmless the owner of
such primary obligation against loss in respect thereof; provided, however, that the term Contingent Liability shall not include endorsements of instruments for deposit or collection in the ordinary course of business. The amount of
any Contingent Liability shall be deemed to be an amount equal to the stated or determinable amount of the primary obligation in respect of which such Contingent Liability is made or, if not stated or determinable, the maximum reasonably anticipated
liability in respect thereof (assuming such Person is required to perform thereunder) as determined by such Person in good faith. 
 “Conversion Price” shall equal $1.00 per Share, as may be adjusted in accordance with the terms of the Note. 
 “Convertible Bridge Notes” means the convertible bridge notes issued by the Company in anticipation of Closing hereunder with an outstanding unpaid principal balance of $1,500,000. 
 “Disclosure Schedules” means the Disclosure Schedules of the Company delivered concurrently herewith. 
 “Discussion Time” shall have the meaning ascribed to such term in Section 3.2(h). 
 “Effective Date” means the date that the initial Registration Statement filed by the Company pursuant to the Registration
Rights Agreement is first declared effective by the Commission. 
 “ERISA” means the Employee Retirement
Income Security Act of 1974, as amended, or any successor statute. 
  

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 “ERISA Group” means the Company and each Subsidiary and all members of a
controlled group of corporations and all trades or businesses (whether or not incorporated) under common control which, together with the Company or any Subsidiary, are treated as a single employer under the Code. 
 “Evaluation Date” shall have the meaning ascribed to such term in Section 3.1(s). 
 “Exchange Act” means the Securities Exchange Act of 1934, as amended, and the rules and regulations promulgated
thereunder. 
 “Exempt Issuance” means the issuance of (a) shares of Common Stock or options to
employees, officers or directors of the Company pursuant to any employment agreement, equity incentive plan or option plan approved by stockholders of the Company or duly adopted by a majority of the non-employee members of the Board of Directors of
the Company or a majority of the members of a committee of non-employee directors established for such purpose, (b) securities upon the exercise or exchange of or conversion of any Securities issued hereunder and/or other securities exercisable
or exchangeable for or convertible into shares of Common Stock issued and outstanding on the date of this Agreement, provided that such securities have not been amended since the date of this Agreement to increase the number of such securities or to
decrease the exercise, exchange or conversion price of any such securities, and (c) securities issued pursuant to the Allendale Acquisition Agreement or any acquisitions or strategic transactions approved by a majority of the disinterested
directors. 
 “GAAP” shall have the meaning ascribed to such term in Section 3.1(h). 
 “Guarantor” shall have the meaning set forth in the Guarantee Agreement. 
 “Guarantee Agreement” means that certain Guarantee Agreement by and among the Company, Synova Healthcare, Inc., Synova
Pre-Natal Healthcare, Inc., the Purchasers and any future Guarantors as set forth in the Guarantee Agreement. 
 “Indebtedness” of any Person shall mean, without duplication, (a) all obligations of such Person for borrowed money or with respect to deposits or advances of any kind, (b) all obligations of such Person evidenced
by bonds, debentures, notes or similar instruments, (c) all obligations of such Person upon which interest charges are customarily paid, (d) all obligations of such Person under conditional sale or other title retention agreements relating
to property or assets purchased by such Person, (e) all obligations of such Person issued or assumed as the deferred purchase price of property or services (other than unsecured accounts payable incurred in the ordinary course of business and
no more than ninety (90) days past the date of the invoice therefor), (f) all Indebtedness of others secured by (or for which the holder of such Indebtedness has an existing right, contingent or otherwise, to be secured by) any Lien on
property owned or acquired by such Person, whether or not the obligations secured thereby have been assumed, (g) all obligations of such Person in respect of interest rate protection agreements, foreign currency exchange agreements or other
interest or exchange rate 

  

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hedging arrangements that exceed amounts necessary to hedge the Company’s cross-currency exposure and (h) all obligations of such Person as an
account party in respect of letters of credit and bankers’ acceptances. The Indebtedness of any Person shall include the Indebtedness of any partnership in which such Person is a general partner. 
 “Intellectual Property Rights” shall have the meaning ascribed to such term in Section 3.1(p). 
 “Legend Removal Date” shall have the meaning ascribed to such term in Section 4.1(c). 
 “Liens” means a lien, charge, security interest, encumbrance, right of first refusal, preemptive right or other
restriction or impairment. 
 “Material Adverse Effect” shall have the meaning assigned to such term in
Section 3.1(b). 
 “Material Permits” shall have the meaning ascribed to such term in
Section 3.1(n). 
 “Notes” mean the convertible notes of the Company in the form attached hereto as
Exhibit B, which notes shall be convertible into Shares at the Conversion Price. 
 “Obligations”
means (i) the due and punctual payment of (a) principal of and premium, if any, and interest (including interest accruing during the pendency of any bankruptcy, insolvency, receivership or other similar proceeding, regardless of whether
allowed or allowable in such proceeding) on the Notes, when and as due, whether at maturity, by acceleration, upon one or more dates set for prepayment or otherwise, and (b) all other monetary obligations, including fees, commissions, costs,
expenses and indemnities, whether primary, secondary, direct, contingent, fixed or otherwise (including monetary obligations incurred during the pendency of any bankruptcy, insolvency, receivership or other similar proceeding, regardless of whether
allowed or allowable in such proceeding), of the Company to the Purchasers, in each case under the Transaction Documents, and (ii) the due and punctual performance of all covenants, agreements, obligations and liabilities of the Company and
Guarantors under or pursuant to the Transaction Documents. 
 “Outside Date” means the twentieth calendar day
following the date of this Agreement. 
 “Participation Maximum” shall have the meaning ascribed to such term
in Section 4.12. 
 “PBGC” means the Pension Benefit Guarantee Corporation or any entity succeeding to
any or all of its functions under ERISA. 
 “Permitted Indebtedness” shall have the meaning set forth in
Section 5.3. 
  

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 “Permitted Investments” means: 
 (a) debt obligations and maturing within one year from the date of acquisition thereof to the extent the principal thereof and interest
thereon is backed by the full faith and credit of the United States of America; 
 (b) investments in commercial paper which
mature within 270 days from the date of acquisition thereof and having, at such date of acquisition, the highest credit rating obtainable from Standard & Poor’s Ratings Services, a division of The McGraw Hill Companies, or any
successor thereto, or from Moody’s Investors Service, Inc. or any successor thereto; 
 (c) investments in certificates
of deposit, banker’s acceptances and time deposits maturing within 180 days from the date of acquisition thereof issued or guaranteed by or placed with, and money market deposit accounts issued or offered by, any domestic office of any
commercial bank organized under the laws of the United States of America or any State thereof that has a combined capital and surplus and undivided profits of not less than $500,000,000 or, to the extent not otherwise included, any Lender, and which
is rated at least A-2 by Standard & Poor’s Ratings Services, a division of The McGraw Hill Companies, or any successor thereto, and P-2 by Moody’s Investors Service, Inc. or any successor thereto in the note or commercial paper
rating category, in each case denominated in dollars; 
 (d) fully collateralized repurchase agreements with a term of not
more than 30 days for securities described in clause (a) of this definition and entered into with a financial institution satisfying the criteria described in clause (c) of this definition; and 
 (e) money market mutual funds, 90% of the investments of which are in cash or investments contemplated by clauses (a), (b) and
(c) of this definition. 
 “Person” means an individual or corporation, partnership, trust, incorporated
or unincorporated association, joint venture, limited liability company, joint stock company, government (or an agency or subdivision thereof) or other entity of any kind. 
 “Placement Agent” means BMO Capital Markets Corp. 
 “Plan” means at any time an employee pension plan benefit plan which is covered by Title IV of ERISA or subject to the
minimum funding standards under the Code and either (i) is maintained, or contributed to, by any member of the ERISA group for employees of any member of the ERISA group or (ii) has at any time within the preceding five years been
maintained, or contributed to, by any Person which was at such time a member of the ERISA Group for employees of any Person which was at such time a member of the ERISA group. 
 “Pre-Notice” shall have the meaning ascribed to such term in Section 4.12. 
  

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 “Proceeding” means a claim, suit, arbitration, investigation or
proceeding (including, without limitation, an investigation or partial proceeding, such as a deposition), whether commenced or threatened. 
 “Purchase Price” equals $1.00 for each $1.00 of principal amount of Notes being purchased by the Purchasers at the Closing. 
 “Purchaser Party” shall have the meaning ascribed to such term in Section 4.9. 
 “Registration Rights Agreement” means the Registration Rights Agreement, dated the date hereof, among the Company and the
Purchasers, in the form of Exhibit C attached hereto. 
 “Registration Statement” means a registration
statement meeting the requirements set forth in the Registration Rights Agreement and covering the resale by the Purchasers and their successors in interest and transferees of the Shares and the Warrant Shares. 
 “Required Approvals” shall have the meaning ascribed to such term in Section 3.1(e). 
 “Required Purchasers” means one or more Purchasers representing greater than 70% of the aggregate principal amount of all
Notes then outstanding. 
 “Restricted Payment” means, with respect to any Person, (a) any direct or
indirect distribution, dividend or other payment on account of any equity interest in, or shares of capital stock or other securities of, such Person and (b) any management, consulting or other similar fees, or any interest thereon, payable by
such Person to any affiliate of such Person (other than the Company), or to any other Person other than an unrelated third party; provided, however, that Restricted Payments shall not include any arms length consulting agreements with
consultants of the Company which are approved by the Board of Directors of the Company. 
 “Rule 144” means
Rule 144 promulgated by the Commission pursuant to the Securities Act, as such Rule may be amended from time to time, or any similar rule or regulation hereafter adopted by the Commission having substantially the same effect as such Rule.

 “SEC Reports” shall have the meaning ascribed to such term in Section 3.1(h). 
 “Securities” means the Notes, the Shares, the Warrants and the Warrant Shares. 
 “Securities Act” means the Securities Act of 1933, as amended, and the rules and regulations promulgated thereunder.

 “Senior Bank Indebtedness” means all obligations, liabilities and indebtedness of every nature of the
Company from time to time owed to Wachovia Bank, N.A. under the Senior Bank Indebtedness Documents. 
  

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 “Senior Bank Indebtedness Documents” means the Note and Security
Agreement, each dated as of April 28, 2005, by and between Synova Healthcare, Inc. and Wachovia Bank, National Association, as the same shall have been amended, restated, supplemented or otherwise modified from time to time. 
 “Shares” means the shares of Common Stock issuable upon conversion of the Notes in accordance with the terms of the
Notes. 
 “Short Sales” include, without limitation, all “short sales” as defined in Rule 200
promulgated under Regulation SHO under the Exchange Act and all types of direct and indirect stock pledges, forward sale contracts, options, puts, calls, swaps and similar arrangements (including on a total return basis), and sales and other
transactions through non-US broker dealers or foreign regulated brokers. 
 “Subscription Amount” means, as
to each Purchaser, the aggregate amount of Purchase Price to be paid for Notes and Warrants purchased hereunder as specified below such Purchaser’s name on the signature page of this Agreement and next to the heading “Subscription
Amount”, in United States Dollars and in immediately available funds. 
 “Subsequent Financing” shall
have the meaning ascribed to such term in Section 4.12. 
 “Subsequent Financing Notice” shall have the
meaning ascribed to such term in Section 4.12. 
 “Subsidiary” means any subsidiary of the Company or
Allendale. 
 “Trading Day” means (i) a day on which the Common Stock is traded on an Trading Market,
(ii) if the Common Stock is not listed on an Trading Market, a day on which the Common Stock is traded in the Pink Sheets LLC (or any similar organization or agency succeeding to its functions of reporting prices), or (iii) if the Common
Stock is not reported by the Pink Sheets LLC (or any similar organization or agency succeeding to its functions of reporting prices) then Trading Day shall mean a Business Day 
 “Trading Market” means the following markets or exchanges on which the Common Stock is listed or quoted for trading on
the date in question: the Nasdaq Capital Market, the American Stock Exchange, the New York Stock Exchange, the Nasdaq National Market, or the OTC Bulletin Board. 
 “Transaction Documents” means this Agreement, the Notes, the Warrants, the Registration Rights Agreement, the Guarantee
Agreement, the Lockup Agreements and any other documents or agreements executed in connection with the transactions contemplated hereunder. 
 “Transaction Form 8-K” shall have the meaning ascribed to such term in Section 4.4. 
  

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 “Warrants” means the Company’s Common Stock Purchase Warrants, in
the form of Exhibit D issued to the Purchasers at the Closing in accordance with Section 2.2(a) hereof, which Warrants shall become exercisable immediately upon their date of issuance and shall have a term of exercise equal to five
(5) years from the Closing Date. 
 “Warrant Shares” means the shares of Common Stock issuable upon
exercise of the Warrants. 
 ARTICLE II. 
 PURCHASE AND SALE 
 2.1 Closing. On the Closing Date, upon the terms and subject to the conditions set forth herein, the
Company agrees to sell, and each Purchaser severally (and not jointly) agrees to purchase, the principal amount of Notes and the number of Warrants for the Subscription Amount specified below such Purchaser’s name on the signature page of this
Agreement. Each Purchaser shall deliver to the Company via wire transfer or a certified check immediately available funds equal to its Subscription Amount and the Company shall deliver to each Purchaser its respective Notes and Warrants as
determined pursuant to Section 2.2(a) and the other items set forth in Section 2.2 issuable at the Closing. Upon satisfaction of the conditions set forth in Sections 2.2 and 2.3, the Closing shall occur at the offices of Bryan Cave LLP,
1290 Avenue of the Americas, New York, NY 10104, or such other location as the parties shall mutually agree. 
 2.2 Deliveries.

 (a) On or prior to the Closing Date, the Company shall deliver or cause to be delivered to each Purchaser the following:

 (i) this Agreement duly executed by the Company; 
 (ii) a legal opinion of Company Counsel, in the form of Exhibit E attached hereto; 
 (iii) the Notes (in the principal amounts as such Purchaser shall request or, if no such request is made, a single Note with a principal
amount equal to the aggregate principal amount of the Notes to be purchased by such Purchaser) which such Purchaser is purchasing duly executed on behalf of the Company and registered in the name of such Purchaser or its designee; 
 (iv) a Warrant registered in the name of such Purchaser to purchase up to a number of shares of Common Stock equal to 110% of the Shares
issuable upon conversion of the Notes purchased by such Purchaser (rounded up to the nearest whole number) with an exercise price equal to $1.00, subject to adjustment therein; 
 (v) a lock-up agreement, in the form of Exhibit F attached hereto (the “Lockup Agreements”), duly executed by all
executive officers and directors of the Company and certain shareholders of the Company holding more than 10% of 

  

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the Common Stock (it being understood that the Lockup Agreements to be executed by Stephen King and David Harrison will include modifications necessary to
permit the sales contemplated by Section 3.2(g) above); 
 (vi) a certificate executed by a duly authorized officer of
the Company certifying that (i) all representations and warranties made by the Company and information furnished by the Company in any schedules to this Agreement, are true and correct in all material respects as of the Closing Date,
(ii) all covenants, agreements and obligations required by this Agreement to be performed or complied with by the Company, prior to or at the Closing, have been performed or complied with and (iii) the items referenced in Sections
2.3(b)(iv)-(vii) are true and correct as of the Closing Date; 
 (vii) the Registration Rights Agreement duly executed by
the Company; 
 (viii) the Guarantee Agreement, duly executed by the Company and the Guarantors; 
 (ix) a certificate executed by the corporate secretary or assistant secretary of the Company, certifying as to the Company’s articles
of incorporation, bylaws, and resolutions approving this Agreement; 
 (x) a good standing certificate of the Company issued
within 15 days prior to the Closing Date; 
 (xi) a certificate of the Company’s transfer agent as to the number of
shares of Common Stock issued and outstanding as of the date immediately prior to the Closing Date (or the latest date as to which the transfer agent can provide such information); 
 (xii) a letter of instructions to the Company’s transfer agent as to the reservation of Common Stock required by Section 4.10.

 (b) On or prior to the Closing Date, each Purchaser shall deliver or cause to be delivered to the Company the following:

 (i) this Agreement duly executed by such Purchaser; 
 (ii) such Purchaser’s Subscription Amount by wire transfer to the account specified by the Company; 
 (iii) the Registration Rights Agreement duly executed by such Purchaser; and 
 (iv) the Guarantee duly executed by such Purchaser. 
  

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 2.3 Closing Conditions. 
 (a) The obligations of the Company to perform at the Closing are subject to the following conditions being met or waived by the Company:

 (i) the accuracy when made and on the Closing Date of the representations and warranties of the Purchasers contained
herein; 
 (ii) all obligations, covenants and agreements of the Purchasers required to be performed at or prior to the
Closing Date shall have been performed; and 
 (iii) the delivery by the Purchasers of the items set forth in
Section 2.2(b) of this Agreement. 
 (b) The respective obligations of the Purchasers to perform at the Closing are
subject to the following conditions being met or waived by the Purchasers: 
 (i) the accuracy on the date of this Agreement
and on the Closing Date of the representations and warranties of the Company contained herein; 
 (ii) all obligations,
covenants and agreements of the Company required to be performed at or prior to the Closing Date shall have been performed; 
 (iii) the delivery by the Company of the items set forth in Section 2.2(a) of this Agreement; 
 (iv) there
shall have been no Material Adverse Effect with respect to the Company or Allendale since the date hereof; 
 (v) at least
$15,000,000 of Subscription Amounts shall have been delivered to the Company subject only to the conditions set forth in this Section 2.3; 
 (vi) the Company shall have (i) determined that all conditions to its obligation to close under the Allendale Acquisition Agreement shall have been satisfied (or, to the extent approved by the Purchasers in
writing, waived), (ii) obtained the certified Allendale Financial Statements and delivered copies of the Allendale Financial Statements to the Purchasers, (iii) delivered to the Purchasers copies of such of the other closing deliveries
under the Allendale Acquisition Agreement as the Purchasers shall have requested, and (iv) successfully consummated the simultaneous acquisition of Allendale in accordance with the terms set forth of the Allendale Acquisition Agreement;

 (vii) from the date hereof to the Closing Date, trading in the Common Stock shall not have been suspended by the Commission
or the Company’s principal Trading Market (except for any suspension of trading of not more than one Trading Day agreed to by the Company, which suspension shall be terminated prior to the Closing), and, at any time prior to the Closing Date,
trading in securities generally as reported by Bloomberg Financial Markets shall 

  

 11 

 
not have been suspended or limited, or minimum prices shall not have been established on securities whose trades are reported by such service, or on any
Trading Market, nor shall a banking moratorium have been declared either by the United States or New York State authorities nor shall there have occurred any material outbreak or escalation of hostilities or other national or international calamity
of such magnitude in its effect on, or any material adverse change in, any financial market which, in each case, in the reasonable judgment of the Purchasers, makes it impracticable or inadvisable to purchase the Notes and the Warrants at the
Closing; and 
 (viii) Simultaneously with the Closing, the Company shall have repaid in full, the Senior Bank Indebtedness
and the outstanding Convertible Bridge Notes. 
 ARTICLE III. 
 REPRESENTATIONS AND WARRANTIES 
 3.1 Representations and Warranties of the Company. Except as set
forth under the corresponding section of the disclosure schedules delivered to the Purchasers concurrently herewith or, in regard to Allendale, except as disclosed in its disclosure schedule delivered under the Allendale Acquisition Agreement
(collectively, the “Disclosure Schedules”), which Disclosure Schedules shall be deemed a part hereof, the Company hereby makes the representations and warranties set forth below to each Purchase: 
 (a) Subsidiaries. All of the direct and indirect subsidiaries of each of the Company and Allendale are set forth on Schedule
3.1(a). Each of the Company and Allendale owns, directly or indirectly, all of the capital stock or other equity interests of each of its Subsidiaries free and clear of any Liens, and all the issued and outstanding shares of capital stock of
each Subsidiary are validly issued and are fully paid, non-assessable and free of preemptive and similar rights to subscribe for or purchase securities. If the Company or Allendale have no subsidiaries, then all other references in the Transaction
Documents to the Subsidiaries or any of them as to the Company or Allendale, as the case may be, will be disregarded. 
 (b)
Organization and Qualification. The Company, Allendale and each of the Subsidiaries is an entity duly incorporated or otherwise organized, validly existing and in good standing under the laws of the jurisdiction of its incorporation or
organization (as applicable), with the requisite power and authority to own and use its properties and assets and to carry on its business as currently conducted. None of the Company, Allendale or any Subsidiary is in violation or default of any of
the provisions of its respective certificate or articles of incorporation, bylaws or other organizational or charter documents. Each of the Company, Allendale and the Subsidiaries is duly qualified to conduct business and is in good standing as a
foreign corporation or other entity in each jurisdiction in which the nature of the business conducted or property owned by it makes such qualification necessary, except where the failure to be so qualified or in good standing, as the case may be,
could not have or reasonably be expected to result in (i) a material adverse effect on the legality, validity or enforceability of any Transaction Document or the Allendale Acquisition Agreement, (ii) a material 

  

 12 

 
adverse effect on the results of operations, prospects, assets, business or condition (financial or otherwise) of the Company, Allendale and the
Subsidiaries, taken as a whole, or (iii) a material adverse effect on the Company’s ability to perform in any material respect on a timely basis its obligations under any Transaction Document or the Allendale Acquisition Agreement (any of
(i), (ii) or (iii), a “Material Adverse Effect”) and no Proceeding has been instituted in any such jurisdiction revoking, limiting or curtailing or seeking to revoke, limit or curtail such power and authority or qualification.

 (c) Authorization; Enforcement. The Company and each Subsidiary has the requisite corporate power and authority to
enter into and to consummate (i) the transactions contemplated by each of the Transaction Documents to which it is a party and otherwise to carry out its obligations hereunder and thereunder and (ii) the acquisition of Allendale in
accordance with the Allendale Acquisition Agreement and otherwise to carry out its obligations thereunder. The execution and delivery of each of the Transaction Documents and the Allendale Acquisition Agreement by the Company and the Subsidiaries
and the consummation by them of the transactions contemplated hereby and thereby have been approved by the Board of Directors of the Company and each Subsidiary, as applicable. The execution and delivery of each of the Transaction Documents and the
Allendale Acquisition Agreement by the Company and the consummation by it of the transactions contemplated hereby and thereby have been duly authorized by all necessary action on the part of the Company and no further action is required by the
Company, its board of directors or its stockholders in connection therewith other than in connection with the Required Approvals. Each Transaction Document and the Allendale Acquisition Agreement has been (or upon delivery will have been) duly
executed by the Company and, when delivered in accordance with the terms hereof and thereof, will constitute the valid and binding obligation of the Company enforceable against the Company in accordance with its terms except (i) as limited by
general equitable principles and applicable bankruptcy, insolvency, reorganization, moratorium and other laws of general application affecting enforcement of creditors’ rights generally, (ii) as limited by laws relating to the availability
of specific performance, injunctive relief or other equitable remedies and (iii) insofar as indemnification and contribution provisions may be limited by applicable law. 
 (d) No Conflicts. The execution, delivery and performance of the Transaction Documents and the Allendale Acquisition Agreement by
the Company and the Subsidiaries (as applicable), the issuance and sale of the Notes and Warrants, the Company’s acquisition of Allendale and the consummation by the Company of the other transactions contemplated hereby and thereby do not and
will not (i) conflict with or violate any provision of the Company’s or Subsidiaries’ articles of incorporation, bylaws or other organizational or charter documents, or (ii) conflict with, or constitute a default (or an event
that with notice or lapse of time or both would become a default) under, result in the creation of any Lien upon any of the properties or assets of the Company, Allendale or any Subsidiary, or give to others any rights of termination, amendment,
acceleration or cancellation (with or without notice, lapse of time or both) of, any agreement, credit facility, debt or other instrument (evidencing a Company, Allendale or Subsidiary debt or otherwise) or other understanding to which the Company,
Allendale or any Subsidiary is a party or by which any property or asset of the Company, Allendale or 

  

 13 

 
any Subsidiary is bound or affected, or (iii) subject to the Required Approvals, conflict with or result in a violation of any law, rule, regulation,
order, judgment, injunction, decree or other restriction of any court or governmental authority to which the Company, Allendale or a Subsidiary is subject (including federal and state securities laws and regulations), or by which any property or
asset of the Company, Allendale or a Subsidiary is bound or affected; except in the case of each of clauses (ii) and (iii), such as could not have or reasonably be expected to result in a Material Adverse Effect. 
 (e) Filings, Consents and Approvals. Neither the Company nor any Subsidiary is required to obtain any consent, waiver,
authorization or order of, give any notice to, or make any filing or registration with, any court or other federal, state, local or other governmental authority or other Person in connection with the execution, delivery and performance by the
Company and each Subsidiary (as applicable) of the Transaction Documents and the Allendale Acquisition Agreement, other than (i) filings required pursuant to Sections 4.4 and 4.10 of this Agreement, (ii) the filing with the Commission of
the Registration Statement, (iii) the filing of Form D with the Commission and such filings as are required to be made under applicable state securities laws, (iv) filings provided for in the Allendale Acquisition Agreement,
(v) waivers or consents referred to in Schedule 3.1(e) of the Disclosure Schedules, and (vi) Form 8-K filings (collectively, the “Required Approvals”). 
 (f) Issuance of the Securities. The Notes and the Warrants are duly authorized and, when issued and paid for in accordance with the
applicable Transaction Documents, will be duly and validly issued, free and clear of all Liens imposed by the Company other than restrictions on transfer provided for in the Transaction Documents. The Shares and the Warrant Shares, when issued in
accordance with the terms of the Transaction Documents, will be validly issued, fully paid and nonassessable, free and clear of all Liens imposed by the Company other than restrictions on transfer provided for in the Transaction Documents. The
Company has reserved from its duly authorized capital stock the maximum number of shares of Common Stock issuable pursuant to the Notes and the Warrants. 
 (g) Capitalization. The number of shares and type of all authorized, issued and outstanding capital stock of the Company, and all shares of Common Stock reserved for issuance under the Company’s various
option and incentive plans, is specified in Schedule 3.1(g). No securities of the Company are entitled to preemptive or similar rights, and no Person has any right of first refusal, preemptive right, right of participation, or any similar
right to participate in the transactions contemplated by the Transaction Documents. There are no outstanding options, warrants, scrip rights to subscribe to, calls or commitments of any character whatsoever relating to, or securities, rights or
obligations convertible into or exchangeable for, or giving any Person any right to subscribe for or acquire, any shares of Common Stock, or contracts, commitments, understandings or arrangements by which the Company or any Subsidiary is or may
become bound to issue additional shares of Common Stock, or securities or rights convertible or exchangeable into shares of Common Stock. The issue and sale of the Securities will not, immediately or with the passage of time, obligate the Company to
issue shares of Common Stock or other securities to any Person (other than the 

  

 14 

 
Purchasers) and will not result in a right of any holder of Company securities to adjust the exercise, conversion, exchange or reset price under such
securities. 
 (h) SEC Reports; Financial Statements. The Company has filed all reports, schedules, forms, statements
and other documents required to be filed by it under the Securities Act and the Exchange Act, including pursuant to Section 13(a) or 15(d) thereof, for the period commencing August 12, 2005 through the date hereof (or such shorter period
as the Company was required by law or regulation to file such material) (the foregoing materials, including the exhibits thereto and documents incorporated by reference therein, being collectively referred to herein as the “SEC
Reports”) on a timely basis or has received a valid extension of such time of filing and has filed any such SEC Reports prior to the expiration of any such extension. As of their respective dates, the SEC Reports complied in all material
respects with the requirements of the Securities Act and the Exchange Act and the rules and regulations of the Commission promulgated thereunder, as applicable, and none of the SEC Reports, when filed, contained any untrue statement of a material
fact or omitted to state a material fact required to be stated therein or necessary in order to make the statements therein, in the light of the circumstances under which they were made, not misleading. The financial statements of the Company
included in the SEC Reports and the Allendale Financial Statements comply in all material respects with applicable accounting requirements and the rules and regulations of the Commission with respect thereto as in effect at the time of filing. Such
financial statements have been prepared in accordance with United States generally accepted accounting principles applied on a consistent basis during the periods involved (“GAAP”), except as may be otherwise specified in such
financial statements or the notes thereto and except that unaudited and pro forma financial statements may not contain all footnotes required by GAAP, and fairly present in all material respects the financial position of the Company and Allendale,
as the case may be, and the Company’s and Allendale’s consolidated subsidiaries, as the case may be, as of and for the dates thereof and the results of operations and cash flows for the periods then ended, subject, in the case of unaudited
and pro forma statements, to normal, recurring, year-end audit adjustments and the SEC’s rules on the presentation of unaudited interim financial statements generally. 
 (i) Press Releases. The press releases disseminated by the Company during the twelve months preceding the date of this Agreement
taken as a whole do not contain any untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary in order to make the statements therein, in light of the circumstances under which they were made and
when made, not misleading. 
 (j) Material Changes; Undisclosed Events, Liabilities or Developments. Since the date of
the latest audited financial statements included within the SEC Reports, except as specifically disclosed in a subsequent SEC Report or in the case of Allendale, in the Allendale Financial Statements, (i) there has been no event, occurrence or
development that has had or that could reasonably be expected to result in a Material Adverse Effect, (ii) neither the Company nor Allendale has incurred any liabilities (contingent or otherwise) other than (A) trade payables and accrued
expenses incurred in the ordinary course of business consistent with past practice and (B) liabilities not 

  

 15 

 
required to be reflected in the Company’s financial statements or in the Allendale Financial Statements, as the case may be, pursuant to GAAP or
disclosed by the Company in filings made with the Commission, (iii) the Company has not altered its method of accounting or the identity of its auditors, (iv) neither the Company nor Allendale has declared or made any dividend or
distribution of cash or other property to its stockholders or purchased, redeemed or made any agreements to purchase or redeem any shares of its capital stock and (v) neither the Company nor Allendale has issued any equity securities to any
officer, director or Affiliate, except pursuant to their existing stock option plans. The Company does not have pending before the Commission any request for confidential treatment of information. 
 (k) Litigation. There is no action, suit, inquiry, notice of violation, arbitration, proceeding or investigation pending or, to the
knowledge of the Company, threatened against or affecting the Company, Allendale, any Subsidiary or any of their respective properties before or by any court, arbitrator, governmental or administrative agency or regulatory authority (federal, state,
county, local or foreign) (collectively, an “Action”) which (i) adversely affects or challenges the legality, validity or enforceability of any of the Transaction Documents, the Allendale Acquisition Agreement or the Securities
or (ii) could, if there were an unfavorable decision, have or reasonably be expected to result in a Material Adverse Effect. None of the Company, Allendale or any Subsidiary, nor any director or officer thereof, is or has been the subject of
any Action involving a claim of violation of or liability under federal or state securities laws or a claim of breach of fiduciary duty. There has not been, and to the knowledge of the Company, there is not pending or contemplated, any investigation
by the Commission involving the Company or any current or former director or officer of the Company. The Commission has not issued any stop order or other order suspending the effectiveness of any registration statement filed by the Company or any
Subsidiary under the Exchange Act or the Securities Act. 
 (l) Labor Relations. No material labor dispute exists or,
to the knowledge of the Company, is imminent with respect to any of the employees of the Company or Allendale which could reasonably be expected to result in a Material Adverse Effect. None of the Company’s, Allendale’s or either of their
Subsidiaries’ employees is a member of a union that relates to such employee’s relationship with the Company or Allendale, as the case may be, and none of the Company, Allendale or any of their Subsidiaries is a party to a collective
bargaining agreement, and the Company and its Subsidiaries believe that their relationships with their employees are good. No executive officer, to the knowledge of the Company, is, or is now expected to be, in violation of any material term of any
employment contract, confidentiality, disclosure or proprietary information agreement or non-competition agreement, or any other contract or agreement or any restrictive covenant, and the continued employment of each such executive officer does not
subject the Company, Allendale or any of their Subsidiaries to any liability with respect to any of the foregoing matters. The Company, Allendale and their Subsidiaries are in compliance with all U.S. federal, state, local and foreign laws and
regulations relating to employment and employment practices, terms and conditions of employment and wages and hours, except where the failure to be in compliance could not, individually or in the aggregate, reasonably be expected to have a Material
Adverse Effect. 
  

 16 

 (m) Compliance. None of the Company, Allendale or any of their Subsidiaries
(i) is in default under or in violation of (and no event has occurred that has not been waived that, with notice or lapse of time or both, would result in a default by the Company, Allendale or any of their Subsidiaries under), nor has the
Company, Allendale or any Subsidiary received notice of a claim that it is in default under or that it is in violation of, any indenture, loan or credit agreement or any other agreement or instrument to which it is a party or by which it or any of
its properties is bound (whether or not such default or violation has been waived), (ii) is in violation of any order of any court, arbitrator or governmental body, or (iii) is or has been in violation of any statute, rule or regulation of
any governmental authority, including, without limitation, all foreign, federal, state and local laws applicable to its business and all such laws that affect the environment, except in each case as could not, individually or in the aggregate, have
or reasonably be expected to result in a Material Adverse Effect. The Company is in compliance with all effective requirements of the Sarbanes-Oxley Act of 2002, as amended, and the rules and regulations thereunder, that are applicable to it, except
where such noncompliance could not have or reasonably be expected to result in a Material Adverse Effect. 
 (n) Regulatory
Permits. The Company, Allendale and their Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as
described in the SEC Reports or the Allendale Acquisition Agreement (“Material Permits”), and none of the Company, Allendale nor any Subsidiary has received any notice of any Action relating to the revocation or modification of any
Material Permit. 
 (o) Title to Assets. The Company, Allendale and the Subsidiaries have good and marketable title in
fee simple to all real property owned by them that is material to the business of the Company, Allendale and the Subsidiaries and good and marketable title in all personal property owned by them that is material to the business of the Company,
Allendale and the Subsidiaries, in each case free and clear of all Liens, other than (i) Liens as do not materially affect the value of such property and do not materially interfere with the use made and proposed to be made of such property by
the Company, Allendale and the Subsidiaries, (ii) as described in Section 5.4 and (iii) Liens securing Permitted Indebtedness. Any real property and facilities held under lease by the Company, Allendale and the Subsidiaries are held
by them under valid, subsisting and enforceable leases with which the Company, Allendale and the Subsidiaries are in compliance. 
 (p) Patents and Trademarks. The Company, Allendale and the Subsidiaries have, or have rights to use, all patents, patent applications, trademarks, trademark applications, service marks, trade names, trade secrets, inventions,
copyrights, licenses and other intellectual property rights and similar rights necessary or material for use in connection with their respective businesses as described in the SEC Reports and in the case of Allendale, the Allendale Financial
Statements and which the failure to so have could, individually or in the aggregate, have or reasonably be expected to result in, a Material Adverse Effect (collectively, the “Intellectual Property Rights”). None of the Company,
Allendale or any Subsidiary has received a notice (written or otherwise) that 

  

 17 

 
the Intellectual Property Rights used by the Company, Allendale or any Subsidiary violates or infringes upon the rights of any Person. All such Intellectual
Property Rights are enforceable and to the knowledge of the Company, there is no existing infringement by another Person of any of the Intellectual Property Rights. The Company, Allendale and its Subsidiaries have taken reasonable security measures
to protect the secrecy, confidentiality and value of all of their respective Intellectual Property Rights. 
 (q)
Insurance. Each of the Company, Allendale and their respective Subsidiaries is insured by insurers of recognized financial responsibility against such losses and risks and in such amounts as are prudent and customary in the businesses in
which the Company, Allendale and their Subsidiaries are engaged, including, but not limited to, directors and officers insurance coverage at the level set forth in Schedule 3.1(q). None of the Company, Allendale or any Subsidiary has any
reason to believe that it will not be able to renew its existing insurance coverage as and when such coverage expires or to obtain similar coverage from similar insurers as may be necessary to continue its business without a significant increase in
cost on terms consistent with market for the Company’s and such Subsidiaries’ respective lines of business. 
 (r)
Transactions With Affiliates and Employees. Except as set forth in the SEC Reports, the Allendale Financial Statements, and the licensing arrangements with Dr. Robert Staab disclosed pursuant to the Allendale Acquisition Agreement, none
of the officers or directors of the Company or Allendale and, to the knowledge of the Company, none of the employees of the Company or Allendale is presently a party to any transaction with the Company, Allendale or any of their Subsidiaries (other
than for services as employees, officers and directors), including any contract, agreement or other arrangement providing for the furnishing of services to or by, providing for rental of real or personal property to or from, or otherwise requiring
payments to or from any officer, director or such employee or, to the knowledge of the Company, any entity in which any officer, director, or any such employee has a substantial interest or is an officer, director, trustee or partner, in each case
in excess of $60,000 other than (i) for payment of salary or consulting fees for services rendered, (ii) reimbursement for expenses incurred on behalf of the Company, Allendale or any of their Subsidiaries, as the case may be, and
(iii) for other employee benefits, including stock option agreements under any stock option plan of the Company or Allendale, as the case may be. 
 (s) Sarbanes-Oxley; Internal Accounting Controls. The Company is in material compliance with all provisions of the Sarbanes-Oxley Act of 2002 which are applicable to it as of the Closing Date. Each of the
Company, Allendale and their respective Subsidiaries maintain a system of internal accounting controls sufficient to provide reasonable assurance that (i) transactions are executed in accordance with management’s general or specific
authorizations, (ii) transactions are recorded as necessary to permit preparation of financial statements in conformity with GAAP and to maintain asset accountability, (iii) access to assets is permitted only in accordance with
management’s general or specific authorization, and (iv) the recorded accountability for assets is compared with the existing assets at reasonable intervals and appropriate action is taken with respect to any differences. The Company has
established disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) for the 

  

 18 

 
Company and its Subsidiaries and designed such disclosure controls and procedures to provide a reasonable level of assurance that information required to be
disclosed by the Company in the reports it files or submits under the Exchange Act is recorded, processed, summarized and reported, within the time periods specified in the Commission’s rules and forms. The Company’s certifying officers
have evaluated the effectiveness of such disclosure controls and procedures as of the end of the period covered by the Company’s most recently filed periodic report under the Exchange Act (such date, the “Evaluation Date”). The
Company presented in its most recently filed periodic report under the Exchange Act the conclusions of the certifying officers about the effectiveness of the disclosure controls and procedures based on their evaluations as of the Evaluation Date.
Since the Evaluation Date, there have been no changes in the Company’s, Allendale’s, or their respective Subsidiaries’ internal control over financial reporting (as such term is defined in the Exchange Act) that has materially
affected, or is reasonably likely to materially affect, the Company’s internal control over financial reporting. 
 (t)
Solvency. After giving effect to this Agreement, (i) the Company’s and each Subsidiary’s assets do not constitute unreasonably small capital to carry on its business for the current fiscal year as now conducted and as proposed
to be conducted including its capital needs taking into account the particular capital requirements of the business conducted by the Company and each Subsidiary, and projected capital requirements and capital availability thereof, and (ii) the
current cash flow of the Company and each Subsidiary, together with the proceeds the Company and each Subsidiary would receive, were it to liquidate all of its assets, after taking into account all anticipated uses of the cash, would be sufficient
to pay all amounts on or in respect of its debt when such amounts are required to be paid. Neither the Company nor any Subsidiary has a current intention to incur debts beyond its ability to pay such debts as they mature (taking into account the
timing and amounts of cash to be payable on or in respect of its debt). 
 (u) Certain Fees. Except as set forth in
Schedule 3.1(u), no brokerage or finder’s fees or commissions are or will be payable by the Company to any broker, financial advisor or consultant, finder, placement agent, investment banker, bank or other Person with respect to the
transactions contemplated by the Transaction Documents or the Allendale Acquisition Agreement. The Purchasers shall have no obligation with respect to any fees or with respect to any claims made by or on behalf of any Person for fees of a type
contemplated in this Section that may be due in connection with the transactions contemplated by the Transaction Documents. 
 (v) Investment Company. Neither the Company nor any Subsidiary is, nor is an Affiliate of, and immediately after receipt of payment for the Securities, will not be or be an Affiliate of, an “investment company”
within the meaning of the Investment Company Act of 1940, as amended. The Company and each Subsidiary shall conduct its business in a manner so that it will not become subject to the Investment Company Act. 
 (w) Certain Registration Matters. Assuming the accuracy of the Purchasers’ representations and warranties set forth in
Section 3.2(b)-(e), no registration under the Securities Act is required for the offer and sale of the Securities by the Company to the 

  

 19 

 
Purchasers under the Transaction Documents. The Company is eligible to register the resale of its Common Stock for resale by the Purchasers under Form SB-2
promulgated under the Securities Act. Except as set forth in Schedule 3.1(w), the Company has not granted or agreed to grant to any Person any rights (including “piggy-back” registration rights) to have any securities of the
Company registered with the Commission or any other governmental authority that have not been satisfied or exercised. 
 (x)
Listing and Maintenance Requirements. The Company’s Common Stock is registered pursuant to Section 12(b) or 12(g) of the Exchange Act, and the Company has taken no action designed to, or which to its knowledge is likely to have the
effect of, terminating the registration of the Common Stock under the Exchange Act nor has the Company received any notification that the Commission is contemplating terminating such registration. The Company has not, in the 24 months preceding the
date hereof, received notice from any Trading Market on which the Common Stock is or has been listed or quoted to the effect that the Company is not in compliance with the listing or maintenance requirements of such Trading Market. The Company is,
and has no reason to believe that it will not in the foreseeable future continue to be, in compliance with all such listing and maintenance requirements. The issuance and sale of the Securities under the Transaction Documents does not contravene the
rules and regulations of the Trading Market on which the Common Stock is currently listed or quoted, and no approval of the shareholders of the Company thereunder is required for the Company to enter into and to consummate the transactions
contemplated by the Transaction Documents, including, without limitation, to issue and deliver to the Purchasers the Securities contemplated by the Transaction Documents. 
 (y) Application of Takeover Protections. The Company and its Board of Directors have taken all necessary action, if any, in order
to render inapplicable any control share acquisition, business combination, poison pill (including any distribution under a rights agreement) or other similar anti-takeover provision under the Company’s Certificate of Incorporation (or similar
charter documents) or the laws of its state of incorporation that is or could become applicable to the Purchasers as a result of the Purchasers and the Company fulfilling their obligations or exercising their rights under the Transaction Documents,
including without limitation as a result of the Company’s issuance of the Securities and the Purchasers’ ownership of the Securities. 
 (z) No Additional Agreements. Neither the Company nor any Subsidiary has any agreement or understanding with any Purchaser with respect to the transactions contemplated by the Transaction Documents other than
as specified in the Transaction Documents. 
 (aa) No Integrated Offering. Assuming the accuracy of the
Purchasers’ representations and warranties set forth in Section 3.2, neither the Company, nor any of its affiliates, nor any Person acting on its or their behalf has, directly or indirectly, made any offers or sales of any security or
solicited any offers to buy any security, under circumstances that would cause this offering of the Securities to be integrated with prior offerings by the Company for purposes of (i) the Securities Act in a manner which would cause this
offering to fail to be exempt from the registration requirements of Section 5 of 

  

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the Securities Act or (ii) any applicable shareholder approval provisions of any Trading Market on which any of the securities of the Company are listed
or designated. 
 (bb) Tax Status. Except for matters that would not, individually or in the aggregate, have or
reasonably be expected to result in a Material Adverse Effect, the Company, Allendale and each Subsidiary has filed all necessary federal, state and foreign income and franchise tax returns and has paid or accrued all taxes shown as due thereon, and
the Company has no knowledge of a tax deficiency which has been asserted or threatened against the Company, Allendale or any Subsidiary. 
 (cc) No General Solicitation. Neither the Company nor any Person acting on behalf of the Company has offered or sold any of the Securities by any form of general solicitation or general advertising. The Company
has offered the Securities for sale only to the Purchasers and certain other “accredited investors” within the meaning of Rule 501 under the Securities Act. 
 (dd) Foreign Corrupt Practices. Neither the Company nor Allendale, nor to the knowledge of the Company, any agent or other person
acting on behalf of the Company or Allendale, has (i) directly or indirectly, used any funds for unlawful contributions, gifts, entertainment or other unlawful expenses related to foreign or domestic political activity, (ii) made any
unlawful payment to foreign or domestic government officials or employees or to any foreign or domestic political parties or campaigns from corporate funds, (iii) failed to disclose fully any contribution made by the Company or Allendale (or
made by any person acting on its behalf of which the Company is aware) which is in violation of law, or (iv) violated in any material respect any provision of the Foreign Corrupt Practices Act of 1977, as amended. 
 (ee) Accountants. The Company’s current independent accounting firm is Morison Cogen LLP. To the knowledge of the Company,
such accountants, who the Company expects will express their opinion with respect to the financial statements to be included in the Company’s Annual Report on Form 10-K for the year ending December 31, 2006, are a registered public
accounting firm as required by the Exchange Act. The Company has consulted its independent auditors concerning the accounting treatment of the transactions contemplated by the Transaction Documents, and in connection therewith has furnished such
auditors complete copies of the Transaction Documents. 
 (ff) Acknowledgment Regarding Purchasers’ Purchase of
Securities. The Company acknowledges and agrees that each of the Purchasers is acting solely in the capacity of an arm’s length purchaser with respect to the Transaction Documents and the transactions contemplated thereby. The Company
further acknowledges that no Purchaser is acting as a financial advisor or fiduciary of the Company (or in any similar capacity) with respect to the Transaction Documents and the transactions contemplated thereby and any advice given by any
Purchaser or any of their respective representatives or agents in connection with the Transaction Documents and the transactions contemplated thereby is merely incidental to the Purchasers’ purchase of the Securities. The Company further
represents to each Purchaser that the Company’s decision to enter into this Agreement and the other Transaction Documents has been based solely on the 

  

 21 

 
independent evaluation of the transactions contemplated hereby by the Company and its representatives. 
 (gg) Manipulation of Price. The Company has not, and to its knowledge no one acting on its behalf has, (i) taken,
directly or indirectly, any action designed to cause or to result in the stabilization or manipulation of the price of any security of the Company to facilitate the sale or resale of any of the Securities, or (ii) paid or agreed to pay to any
person any compensation for soliciting another to purchase any other securities of the Company, other than, in the case of clause (ii), compensation paid to placement agents acting on the Company’s behalf in connection with the placement of
securities of the Company, including, without limitation, the Securities being sold pursuant to this Agreement and compensation paid to investor relations firms. 
 (hh) Material Contracts. Each of the contracts described in the SEC Reports that are material to the Company and the Allendale
Contracts are in full force and effect, and neither the Company nor Allendale, nor to the Company’s knowledge, any other party to such contracts is in breach of or in default, or received a notice of termination under any such contracts which
would have a Material Adverse Effect. The Company has filed with the SEC all contracts and agreements required to be filed by the Exchange Act. 
 (ii) Absence of Any Undisclosed Liabilities or Capital Calls. Except for Actions described in the SEC Reports, there are no liabilities of the Company or any Subsidiary of any kind whatsoever, whether accrued,
contingent, absolute, determined, determinable or otherwise, and there is no existing condition, situation or set of circumstances which could reasonably be expected to result in such a liability, other than (i) those liabilities provided for
in the Company’s financial statements, (ii) liabilities arising in the ordinary course of business since the date of the most recently publicly filed audited financial statements of the Company, and (iii) other undisclosed liabilities
which, individually or in the aggregate, could not have, or reasonably be expected to result in, a Material Adverse Effect. 
 (jj) Secured Indebtedness. As of the Closing Date, the Company has no Indebtedness that is secured by any Lien, other than Permitted Indebtedness. 
 (kk) Compliance with ERISA. 
 (i) Each member of the ERISA Group has fulfilled its obligations under the minimum funding standards of ERISA and the Code with respect to each Plan and is in compliance in all material respects with the presently
applicable provisions of ERISA and the Code with respect to each Plan. No member of the ERISA Group has (i) sought a waiver of the minimum funding standard under Section 412 of the Code in respect of any Plan, (ii) failed to make any
required contribution or payment to any Plan or multiemployer Plan or in respect of any Benefit Arrangement, or made any amendment to any Plan or Benefit Arrangement, which has resulted or could result in the imposition of a Lien or the posting of a
bond or other security under ERISA or the Code or (iii)

  

 22 

 
incurred any liability under Title IV of ERISA other than a liability to the PBGC for premiums under Section 4007 of ERISA. 
 (ii) The benefit plans not covered under clause (a) above (including profit sharing, deferred compensation, stock option, employee
stock purchase, bonus, retirement, health or insurance plans, collectively the “Benefit Plans”) relating to the employees of the Company are duly registered where required by, and are in good standing in all material respects under,
all applicable laws. All required employer and employee contributions and premiums under the Benefit Plans to the date hereof have been made, the respective fund or funds established under the Benefit Plans are funded in accordance with applicable
laws, and no past service funding liabilities exist thereunder. 
 (iii) No Benefit Plans have any unfunded liabilities,
either on a “going concern” or “winding up” basis and determined in accordance with all applicable laws and actuarial practices and using actuarial assumptions and methods that are reasonable in the circumstances.
No event has occurred and no condition exists with respect to any Benefit Plans that has resulted or could reasonably be expected to result in any pension plan having its registration revoked or wound up (in whole or in part) or refused for the
purposes of any applicable laws or being placed under the administration of any relevant pension benefits regulatory authority or being required to pay any taxes or penalties (in any material amounts) under any applicable laws. 
 (ll) Ranking of the Notes. No Indebtedness of the Company is senior to the Notes in right of payment, whether with respect to
payment of redemptions, interest, damages or upon liquidation or dissolution or otherwise. 
 (mm) Disclosure. Except
with respect to the material terms and conditions of the transactions contemplated by the Transaction Documents and information concerning the Company and Allendale, each of which will be contained in the Form 8-Ks filed by the Company pursuant to
Section 4.4 hereof, the Company confirms that, neither it nor any other Person acting on its behalf has provided any of the Purchasers or their agents or counsel with any information that it believes constitutes or might constitute material,
non-public information. The Company understands and confirms that the Purchasers will rely on the foregoing representation in effecting transactions in securities of the Company. All disclosure furnished by or on behalf of the Company to the
Purchasers regarding the Company, its business and the transactions contemplated hereby, including the Disclosure Schedules to this Agreement, with respect to the representations and warranties made herein, are true and correct and do not contain
any untrue statement of a material fact or omit to state any material fact necessary in order to make the statements made therein, in light of the circumstances under which they were made, not misleading. The Company acknowledges and agrees that no
Purchaser makes or has made any representations or warranties with respect to the transactions contemplated hereby other than those specifically set forth in Section 3.2 hereof. 
  

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 3.2 Representations and Warranties of the Purchasers. Each Purchaser hereby, for itself and for no
other Purchaser, represents and warrants as of the date hereof and as of the Closing Date to the Company as follows: 
 (a)
Organization; Authority. Such Purchaser is an entity duly organized, validly existing and in good standing under the laws of the jurisdiction of its organization with full right, corporate or partnership power and authority to enter into and
to consummate the transactions contemplated by the Transaction Documents and otherwise to carry out its obligations hereunder and thereunder. The execution, delivery and performance by such Purchaser of the transactions contemplated by this
Agreement have been duly authorized by all necessary corporate or similar action on the part of such Purchaser. Each Transaction Document to which it is a party has been duly executed by such Purchaser, and when delivered by such Purchaser in
accordance with the terms hereof, will constitute the valid and legally binding obligation of such Purchaser, enforceable against it in accordance with its terms, except (i) as limited by general equitable principles and applicable bankruptcy,
insolvency, reorganization, moratorium and other laws of general application affecting enforcement of creditors’ rights generally, (ii) as limited by laws relating to the availability of specific performance, injunctive relief or other
equitable remedies and (iii) insofar as indemnification and contribution provisions may be limited by applicable law. 
 (b) Own Account. Such Purchaser understands that the Securities are “restricted securities” and have not been registered under the Securities Act or any applicable state securities law and is acquiring the Securities
as principal for its own account and not with a view to or for distributing or reselling such Securities or any part thereof in violation of the Securities Act or any applicable state securities law, has no present intention of distributing any of
such Securities in violation of the Securities Act or any applicable state securities law and has no direct or indirect arrangement or understandings with any other Persons to distribute or regarding the distribution of such Securities (this
representation and warranty not limiting such Purchaser’s right to sell the Securities pursuant to the Registration Statement or otherwise in compliance with applicable federal and state securities laws) in violation of the Securities Act or
any applicable state securities law. Such Purchaser is acquiring the Securities hereunder in the ordinary course of its business. 
 (c) Purchaser Status. At the time such Purchaser was offered the Securities, it was, and at the date hereof it is, an “accredited investor” as defined in Rule 501(a) under the Securities Act. Such Purchaser is not a
registered broker-dealer under Section 15 of the Exchange Act. 
 (d) Experience of Such Purchaser. Such
Purchaser, either alone or together with its representatives, has such knowledge, sophistication and experience in business and financial matters so as to be capable of evaluating the merits and risks of the prospective investment in the Securities,
and has so evaluated the merits and risks of such investment. Such Purchaser is able to bear the economic risk of an investment in the Securities and, at the present time, is able to afford a complete loss of such investment. 
  

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 (e) General Solicitation. Such Purchaser is not purchasing the Securities as a
result of any advertisement, article, notice or other communication regarding the Securities published in any newspaper, magazine or similar media or broadcast over television or radio or presented at any seminar or any other general solicitation or
general advertisement. No solicitation, offer to sell or offer to purchase was made to or from Purchaser with respect to the Securities other than in the Commonwealth of Pennsylvania, the State of California or the state of Purchaser’s domicile
as set forth on the signature page. 
 (f) Access to Information. Such Purchaser acknowledges that it has reviewed the
SEC Reports and has been afforded (i) the opportunity to ask such questions as it has deemed necessary of, and to receive answers from, representatives of the Company concerning the terms and conditions of the offering of the Securities and the
merits and risks of investing in the Securities; (ii) access to information about the Company and the Subsidiaries and their respective financial condition, results of operations, business, properties, management and prospects sufficient to
enable it to evaluate its investment; and (iii) the opportunity to obtain such additional information that the Company possesses or can acquire without unreasonable effort or expense that is necessary to make an informed investment decision
with respect to the investment. Neither such inquiries nor any other investigation conducted by or on behalf of such Purchaser or its representatives or counsel shall modify, amend or affect such Purchaser’s right to rely on the truth, accuracy
and completeness of the Disclosure Materials and the Company’s representations and warranties contained in the Transaction Documents. 
 (g) King/Harrison Sales. Such Purchaser has acknowledged and agreed that Stephen King and David Harrison shall be each be entitled, notwithstanding any provision in the Transaction Documents to the contrary, to sell
up to 50,000 shares of Common Stock per calendar quarter. 
 (h) Certain Trading Activities. Other than the transaction
contemplated hereunder, such Purchaser has not directly or indirectly, nor has any Person acting on behalf of or pursuant to any understanding with such Purchaser, executed any disposition, including Short Sales, in the securities of the
Company during the period commencing from the time that such Purchaser first received a term sheet (written or oral) from the Company or any other Person setting forth the material terms of the transactions contemplated hereunder until the date
hereof (“Discussion Time”). Other than to other Persons party to this Agreement and their respective counsel and Affiliates, such Purchaser has maintained the confidentiality of all disclosures made to it in connection with this
transaction (including the existence and terms of this transaction). 
 ARTICLE IV. 
 OTHER AGREEMENTS OF THE PARTIES 
 4.1 Transfer Restrictions. 
 (a) The Securities may only be disposed of in compliance with state and federal securities laws. In connection with any transfer of
Securities other than pursuant 

  

 25 

 
to an effective registration statement or Rule 144, to the Company or to an affiliate of a Purchaser or in connection with a pledge as contemplated in
Section 4.1(b), the Company may require the transferor thereof to provide, at the transferor’s expense, to the Company an opinion of counsel selected by the transferor and reasonably acceptable to the Company, the form and substance of
which opinion shall be reasonably satisfactory to the Company, to the effect that such transfer does not require registration of such transferred Securities under the Securities Act, and may also require Purchaser to provide such additional
documents, certificates, or other instruments as may be reasonably necessary and customary to demonstrate compliance with Rule 144. As a condition of transfer, any such transferee shall agree in writing to be bound by the terms of this Agreement and
shall have the rights of a Purchaser under this Agreement and the Registration Rights Agreement. 
 (b) The Purchasers agree
to the imprinting, so long as is required by this Section 4.1, of a legend on any of the Securities in the following form: 
 [NEITHER
THESE SECURITIES NOR THE SECURITIES ISSUABLE UPON CONVERSION OR EXERCISE OF THESE SECURITIES HAVE BEEN REGISTERED] [THESE SECURITIES HAVE NOT BEEN REGISTERED] WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN
RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE
SECURITIES ACT OR PURSUANT TO AN AVAILABLE EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT AND IN ACCORDANCE WITH APPLICABLE STATE SECURITIES LAWS AS EVIDENCED BY A LEGAL OPINION OF COUNSEL TO
THE TRANSFEROR TO SUCH EFFECT, THE SUBSTANCE OF WHICH SHALL BE REASONABLY ACCEPTABLE TO THE COMPANY. [THESE SECURITIES AND THE SECURITIES ISSUABLE UPON CONVERSION OR EXERCISE OF THESE SECURITIES] [THESE SECURITIES] MAY BE PLEDGED IN CONNECTION WITH
A BONA FIDE MARGIN ACCOUNT SECURED BY SUCH SECURITIES. 
 The Company acknowledges and agrees that a Purchaser may from time
to time pledge, and/or grant a security interest in some or all of the Securities pursuant to a bona fide margin agreement in connection with a bona fide margin account and, if required under the terms of such agreement or account, such Purchaser
may transfer pledged or secured Securities to the pledgees or secured parties. Such a pledge or transfer would not be subject to approval or consent of the Company and no legal opinion of legal counsel to the pledgee, secured party or pledgor shall
be required in connection with the pledge, but such legal opinion may be required in connection with a subsequent transfer following default by the Purchaser transferee of the pledge. No notice shall be required of such pledge. At the appropriate
Purchaser’s expense, the Company will execute and deliver 

  

 26 

 
such reasonable documentation as a pledgee or secured party of Securities may reasonably request in connection with a pledge or transfer of the Securities
including the preparation and filing of any required prospectus supplement under Rule 424(b)(3) of the Securities Act or other applicable provision of the Securities Act to appropriately amend the list of selling stockholders thereunder. 

(c) Certificates evidencing Underlying Shares and Warrant Shares shall not contain any legend (including the legend set forth in
Section 4.1(b)): (i) while a registration statement (including the Registration Statement) covering such Underlying Shares or Warrant Shares is then effective, or (ii) following a sale or transfer of such Securities pursuant to Rule
144 (assuming the transferor is not an Affiliate of the Company), or (iii) while such Securities are eligible for sale under Rule 144(k). If a Purchaser shall make a sale or transfer of Shares either (x) pursuant to Rule 144 or
(y) pursuant to a registration statement and in each case shall have delivered to the Company or the Company’s transfer agent the certificate representing Shares containing a restrictive legend which are the subject of such sale or
transfer and a representation letter in customary form (the date of such sale or transfer and Share delivery being the “Share Delivery Date”) and (1) the Company shall fail to deliver or cause to be delivered to such Purchaser
a certificate representing such Shares that is free from all restrictive or other legends by the third Trading Day following the Share Delivery Date and (2) following such third Trading Day after the Share Delivery Date and prior to the time
such Shares are received free from restrictive legends, the Purchaser, or any third party on behalf of such Purchaser, purchases (in an open market transaction or otherwise) shares of Common Stock to deliver in satisfaction of a sale by the
Purchaser of such Shares (a “Buy-In”), then the Company shall pay in cash to the Purchaser (for costs incurred either directly by such Purchaser or on behalf of a third party) the amount by which the total purchase price paid for
Common Stock as a result of the Buy-In (including brokerage commissions, if any) exceed the proceeds received by such Purchaser as a result of the sale to which such Buy-In relates. The Purchaser shall provide the Company written notice indicating
the amounts payable to the Purchaser in respect of the Buy-In. The Company may not make any notation on its records or give instructions to any transfer agent of the Company that enlarge the restrictions on transfer set forth in this Section.
Certificates for Securities subject to legend removal hereunder may, if eligible, be transmitted by the transfer agent of the Company to the Purchasers by crediting the account of the Purchaser’s prime broker with the Depository Trust Company
System. 
 (d) Each Purchaser, severally and not jointly with the other Purchasers, agrees that the removal of the restrictive
legend from certificates representing Securities as set forth in this Section 4.1 is predicated upon the Company’s reliance that the Purchaser will sell any Securities pursuant to either the registration requirements of the Securities Act,
including any applicable prospectus delivery requirements, or an exemption therefrom, and that if Securities are sold pursuant to a Registration Statement, they will be sold in compliance with the plan of distribution set forth therein and in
compliance with the prospectus delivery requirements of the Securities Act and applicable law, rules or regulations of any Trading Market. Each Purchaser, severally and not jointly with the other Purchasers, agrees that if it is notified by the
Company at any time after the Legend Removal Date that the registration statement registering the resale of the Shares or the 

  

 27 

 
Warrant Shares is not effective or that the prospectus included in such registration statement no longer complies with the requirements of Section 10 of
the Securities Act or is otherwise materially deficient, such Purchaser will refrain from utilizing the Registration Statement to sell such Shares and Warrant Shares until such time as the Purchaser is notified by the Company that such Registration
Statement is effective or such prospectus is compliant with Section 10 of the Exchange Act or is otherwise no longer materially deficient, unless such Purchaser is able to, and does, sell such Shares or Warrant Shares pursuant to an available
exemption from the registration requirements of Section 5 of the Securities Act. 
 4.2 Furnishing of Information. As long as any
Purchaser owns Securities and reports are required under the Exchange Act, the Company covenants to timely file (or obtain extensions in respect thereof and file within the applicable grace period) all reports required to be filed by the Company
after the date hereof pursuant to the Exchange Act (except with respect to Forms 8-K). As long as any Purchaser owns Securities, if the Company is not required to file reports pursuant to the Exchange Act, it will (i) prepare and furnish to the
Purchasers and make publicly available in accordance with Rule 144(c) such information as is required for the Purchasers to sell the Securities under Rule 144; and (ii) supply annual audited financial statements of the Company to each of the
Purchasers within 90 days after the close of each fiscal year end and quarterly unaudited financial statements within 45 days after the close of each of the first three fiscal quarters, in each case prepared in accordance with GAAP (with the
exception of the exclusion of footnotes and subject to ordinary year end adjustments in the case of quarterly financial statements). The Company further covenants that it will take such further action as any holder of Securities may reasonably
request, to the extent required from time to time to enable such Person to sell such Securities without registration under the Securities Act within the requirements of the exemption provided by Rule 144. 
 4.3 Integration. The Company shall not sell, offer for sale or solicit offers to buy or otherwise negotiate in respect of any security (as defined
in Section 2 of the Securities Act) that would be integrated with the offer or sale of the Securities in a manner that would require the registration under the Securities Act of the sale of the Securities to the Purchasers or that would be
integrated with the offer or sale of the Securities for purposes of the rules and regulations of any Trading Market such that it would require shareholder approval prior to the closing of such other transaction unless shareholder approval is
obtained before the closing of such subsequent transaction. 
 4.4 Securities Laws Disclosure; Publicity. By 9:00 a.m. (New York City
time) on the Trading Day following the execution of this Agreement, and by 9:00 a.m. (New York City time) on the Trading Day following the Closing Date, the Company shall issue press releases in forms approved by the Purchasers disclosing the
transactions contemplated hereby. The Company shall, on the second Trading Day following the date of this Agreement, file with the Commission, (i) a Current Report on Form 8-K, disclosing the material terms of the transactions contemplated
hereby and any material non-public information concerning the Company, Allendale or the Subsidiaries that was provided by the Company to any of the Purchasers, and the Transaction Documents as exhibits to such 8-K (the “Transaction Form
8-K”, together with the Allendale Form 8-K, the “Form 8-K Filings”) and (ii) the Allendale Form 8-K. The Transaction Form 8-K and the Allendale Form 8-K shall be filed concurrently, provided that the 

  

 28 

 
Company may file one Form 8-K disclosing all of the information required to be disclosed in the Transaction Form 8-K and the Allendale Form 8-K. From and
after the filing of the Form 8-K Filings with the Commission, no Purchaser shall be in possession of any material, nonpublic information received from the Company, any of its Subsidiaries or any of their respective officers, directors, employees or
agents, that is not disclosed in the 8-K Filings. The Company shall not, and shall cause each of its Subsidiaries and its and each of their respective officers, directors, employees and agents, not to, provide any Purchaser with any material,
nonpublic information regarding the Company or any of its Subsidiaries from and after the filing of the 8-K Filings with the Commission without the express written consent of such Purchaser. If any Purchaser purchasing at least $2,000,000 in
original principal amount of the Notes at the Closing has, or believes it has, received any such material, nonpublic information regarding the Company or any of its Subsidiaries, it shall promptly provide the Company with written notice thereof. The
Company shall, within five (5) Trading Days of receipt of such notice, make public disclosure of such material, nonpublic information. In the event of a breach of the foregoing covenant by the Company, any of its Subsidiaries, or any of its or
their respective officers, directors, employees and agents, in addition to any other remedy provided herein or in the Transaction Documents, if such Purchaser, in its reasonable judgment and after consultation with legal counsel, determines that it
has material non-public information regarding the Company or any of its Subsidiaries, then such Purchaser shall have the right to make a public disclosure, in the form of a press release, public advertisement or otherwise, of such material,
nonpublic information without the prior approval by the Company, its Subsidiaries, or any of its or their respective officers, directors, employees or agents. No Purchaser shall have any liability to the Company, its Subsidiaries, or any of its or
their respective officers, directors, employees, stockholders or agents for any such disclosure. The Company and each Purchaser shall consult with each other in issuing any other press releases with respect to the transactions contemplated hereby,
and neither the Company nor any Purchaser shall issue any such press release or otherwise make any other such public statement without the prior consent of the Company (except as provided above), with respect to any press release of any Purchaser,
or without the prior consent of each Purchaser, with respect to any press release of the Company, which consent shall not unreasonably be withheld or delayed, except if such disclosure is required by law, in which case the disclosing party shall
promptly provide the other party with prior notice of such public statement or communication. Notwithstanding the foregoing, the Company shall not publicly disclose the name of any Purchaser, or include the name of any Purchaser in any filing with
the Commission or any regulatory agency or Trading Market, without the prior written consent of such Purchaser, except (i) as required by federal securities law in connection with (A) any registration statement contemplated by the
Registration Rights Agreement and (B) the filing of final Transaction Documents (including signature pages thereto) with the Commission and (ii) to the extent such disclosure is required by law or Trading Market regulations, in which case
the Company shall provide the Purchasers with prior notice of such disclosure permitted under this subclause (ii). 
 4.5 Shareholder
Rights Plan. No claim will be made or enforced by the Company or, with the consent of the Company, any other Person, that any Purchaser is an “Acquiring Person” under any control share acquisition, business combination, poison
pill (including any distribution under a rights agreement) or similar anti-takeover plan or arrangement in effect or hereafter adopted by the Company, or that any Purchaser could be deemed to trigger the 

  

 29 

 
provisions of any such plan or arrangement, by virtue of receiving Securities under the Transaction Documents or under any other agreement between the
Company and the Purchasers. 
 4.6 Non-Public Information. Except with respect to information that will be set forth in the Form 8-Ks
to be filed by the Company pursuant to Section 4.4, the Company covenants and agrees that neither it nor any other Person acting on its behalf will provide any Purchaser or its agents or counsel with any information that the Company believes
constitutes material non-public information. The Company understands and confirms that each Purchaser shall be relying on the foregoing representations in effecting transactions in securities of the Company and, in furtherance thereof acknowledges
and agrees that no Purchaser intends to restrict its trading in the securities of the Company in the event of a violation of this Section. 
 4.7 Use of Proceeds. The Company shall use the net proceeds from the sale of the Securities hereunder for the purposes set forth on Schedule 4.7 and, except as set forth on Schedule 4.7, not for the satisfaction of any
portion of the Company’s debt (other than payment of trade payables in the ordinary course of the Company’s business and prior practices and as otherwise required by Section 2.3(b)(viii) hereof), to redeem any Common Stock or Common
Stock Equivalents, to pay any dividends or make any distributions or for any investment not directly related to the business of the Company. 
 4.8 Reimbursement. If any Purchaser becomes involved in any capacity in any Proceeding by or against any Person who is a stockholder of the Company (except as a result of sales, pledges, margin sales and similar transactions by such
Purchaser to or with any other stockholder and except if such claim arises primarily from a breach of such Purchaser’s representations, warranties or covenants under the Transaction Documents or any agreements or understandings such Purchaser
may have with any such stockholder or any violations by the Purchaser of state or federal securities laws or any conduct by such Purchaser which constitutes fraud, gross negligence, willful misconduct or malfeasance), solely as a result of such
Purchaser’s acquisition of the Securities under this Agreement, the Company will reimburse such Purchaser for its reasonable legal and other expenses (including the cost of any investigation preparation and travel in connection therewith)
incurred in connection therewith, as such expenses are incurred. The reimbursement obligations of the Company under this paragraph shall be in addition to any liability which the Company may otherwise have, shall extend upon the same terms and
conditions to any Affiliates of the Purchasers who are actually named in such action, proceeding or investigation, and partners, directors, agents, employees and controlling persons (if any), as the case may be, of the Purchasers and any such
Affiliate, and shall be binding upon and inure to the benefit of any successors, assigns, heirs and personal representatives of the Company, the Purchasers and any such Affiliate and any such Person. The Company also agrees that neither the
Purchasers nor any such Affiliates, partners, directors, agents, employees or controlling persons shall have any liability to the Company or any Person asserting claims on behalf of or in right of the Company solely as a result of acquiring the
Securities under this Agreement, except if such claim arises primarily from a breach of such Purchaser’s representations, warranties or covenants under the Transaction Documents or any agreements or understandings such Purchaser may have with
any such stockholder or any violations by the Purchaser of state or federal securities laws or any conduct by such Purchaser which constitutes fraud, gross negligence, willful misconduct or malfeasance. 
  

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 4.9 Indemnification of Purchasers. Subject to the provisions of this Section 4.9, the Company
will indemnify and hold each Purchaser and its directors, officers, shareholders, members, partners, employees and agents (and any other Persons with a functionally equivalent role of a Person holding such titles notwithstanding a lack of such title
or any other title), each Person who controls such Purchaser (within the meaning of Section 15 of the Securities Act and Section 20 of the Exchange Act), and the directors, officers, shareholders, agents, members, partners or employees
(and any other Persons with a functionally equivalent role of a Person holding such titles notwithstanding a lack of such title or any other title) of such controlling persons (each, a “Purchaser Party”) harmless from any and all
losses, liabilities, obligations, claims, contingencies, damages, costs and expenses, including all judgments, amounts paid in settlements, court costs and reasonable attorneys’ fees and costs of investigation that any such Purchaser Party may
suffer or incur as a result of or relating to (a) any breach of any of the representations, warranties, covenants or agreements made by the Company in this Agreement or in the other Transaction Documents or (b) any action instituted
against a Purchaser, or any of them or their respective Affiliates, by any stockholder of the Company who is not an Affiliate of such Purchaser, with respect to any of the transactions contemplated by the Transaction Documents (unless such action is
based upon a breach of such Purchaser’s representations, warranties or covenants under the Transaction Documents or any agreements or understandings such Purchaser may have with any such stockholder or any violations by the Purchaser of state
or federal securities laws or any conduct by such Purchaser which constitutes fraud, gross negligence, willful misconduct or malfeasance). If any action shall be brought against any Purchaser Party in respect of which indemnity may be sought
pursuant to this Agreement, such Purchaser Party shall promptly notify the Company in writing, and the Company shall have the right to assume the defense thereof with counsel of its own choosing reasonably acceptable to the Purchaser Party. Any
Purchaser Party shall have the right to employ separate counsel in any such action and participate in the defense thereof, but the fees and expenses of such counsel shall be at the expense of such Purchaser Party except to the extent that
(i) the employment thereof has been specifically authorized by the Company in writing, (ii) the Company has failed after a reasonable period of time to assume such defense and to employ counsel or (iii) in such action there is, in the
reasonable opinion of such separate counsel, a material conflict on any material issue between the position of the Company and the position of such Purchaser Party, in which case the Company shall be responsible for the reasonable fees and expenses
of no more than one such separate counsel. The Company will not be liable to any Purchaser Party under this Agreement (i) for any settlement by a Purchaser Party effected without the Company’s prior written consent, or (ii) to the
extent, but only to the extent that a loss, claim, damage or liability is attributable to any Purchaser Party’s breach of any of the representations, warranties, covenants or agreements made by such Purchaser Party in this Agreement or in the
other Transaction Documents. To the extent that the Company becomes liable to multiple Purchaser Parties arising from a common claim, the Company shall make payments to such Purchaser Parties on a pro rata basis, based on the relative unsatisfied
indemnification claim of each such Purchaser Party. Any partial payments made by the Company pursuant to the preceding sentence shall not relieve the Company of the obligation to pay the unsatisfied portion of each such claim. 
 4.10 Reservation of Common Stock. As of the date hereof, the Company has reserved and the Company shall continue to reserve and keep available at
all times, free of preemptive rights, (i) a sufficient number of shares of Common Stock for the purpose of enabling the 

  

 31 

 
Company to issue Shares pursuant to any conversion of the Notes and Warrant Shares pursuant to any exercise of the Warrants, plus (ii) an additional
number of shares of Common Stock equal to at least 20% of the number determined pursuant to clause (i) above. In addition, the Company shall reserve and continue to reserve and keep available at all times a sufficient number of shares of Common
Stock for the purpose of enabling the Company to satisfy its obligations pursuant to each other security or other instrument issued by the Company from time to time which is convertible into or exercisable for Common Stock. 
 4.11 Equal Treatment of Purchasers. No consideration shall be offered or paid to any Person to amend or consent to a waiver or modification of any
provision of any Transaction Document unless the same consideration is also offered to all of the parties to the Transaction Documents. For clarification purposes, this provision constitutes a separate right granted to each Purchaser by the Company
and negotiated separately by each Purchaser, and is intended to treat for the Company the Purchasers as a class and shall not in any way be construed as the Purchasers acting in concert or as a group with respect to the purchase, disposition or
voting of Securities or otherwise. 
 4.12 Participation in Future Financing. 
 (a) From the date hereof until the date that is the 36 month anniversary of the Closing Date, upon any issuance by the Company or any of
its Subsidiaries of Common Stock or Common Stock Equivalents (a “Subsequent Financing”), each Purchaser shall have the right to purchase that percentage of the Common Stock or Common Stock Equivalents issued in the Subsequent
Financing as is equal to the percentage of the outstanding Common Stock of the Company at the time of the Subsequent Financing represented by the Shares or Warrant Shares owned by the Purchaser (assuming for purposes of this calculation that all
Notes had been converted and that all Warrants had been exercised) at the time of the Subsequent Financing (the “Participation Maximum”) on the same terms, conditions and price provided for in the Subsequent Financing. At
least 10 Trading Days prior to the closing of the Subsequent Financing, the Company shall deliver to each Purchaser a written notice of its intention to effect a Subsequent Financing (“Pre-Notice”), which Pre-Notice shall ask
such Purchaser if it wants to review the details of such financing (such additional notice, a “Subsequent Financing Notice”). Upon the request of a Purchaser, and only upon a request by such Purchaser, for a Subsequent
Financing Notice, the Company shall promptly, but no later than 1 Trading Day after such request, deliver a Subsequent Financing Notice to such Purchaser. The Subsequent Financing Notice shall describe in reasonable detail the proposed terms of
such Subsequent Financing, the amount of proceeds intended to be raised thereunder, the Person or Persons through or with whom such Subsequent Financing is proposed to be effected, and attached to which shall be a term sheet or similar document
relating thereto.
 (b) Any Purchaser desiring to participate in such Subsequent Financing must provide written notice to the
Company by not later than 5:30 p.m. (New York City time) on the 5th Trading Day after the Purchaser has received the
Pre-Notice that the Purchaser is willing to participate in the Subsequent Financing, the amount of the Purchaser’s participation, and that the Purchaser has such funds ready, willing, and available for 

  

 32 

 
investment on the terms set forth in the Subsequent Financing Notice. If the Company receives no notice from a Purchaser as of such 5th Trading Day, such Purchaser shall be deemed to have notified the Company that it does not elect to participate.
 (c) If by 5:30 p.m. (New York City time) on the 5th Trading Day after all of the Purchasers have received the Pre-Notice, notifications by the Purchasers of their willingness to participate in the Subsequent Financing are, in the aggregate, less than
the total amount of the aggregate Participation Maximum to which the Purchasers would have been entitled, then the Company may effect the remaining portion of such Subsequent Financing on the terms and with the Persons set forth in the Subsequent
Financing Notice.
 (d) If by 5:30 p.m. (New York City time) on the 5th Trading Day after all of the Purchasers have received the Pre-Notice, the Company receives responses to a Subsequent Financing Notice from Purchasers seeking
to purchase an aggregate amount of the Participation Maximum which would exceed 30% of the Common Stock and Common Stock Equivalents to be issued in the Subsequent Financing, each such Purchaser shall have the right to purchase the greater of
(a) their Pro Rata Portion (as defined below) of the Participation Maximum and (b) the difference between the Participation Maximum and the aggregate amount of participation by all other Purchasers. “Pro Rata Portion”
is the ratio of (x) the Subscription Amount of Securities purchased on the Closing Date by a Purchaser participating under this Section 4.12 and (y) the sum of the aggregate Subscription Amounts of Securities purchased on the Closing
Date by all Purchasers participating under this Section 4.12. 
 (e) The Company shall have 20 Trading Days from the
delivery of the Subsequent Financing Notice to either close and publicly announce the closing of such Subsequent Financing, or abandon such Subsequent Financing and notify the Purchasers of such abandonment such that the Purchasers shall no longer
be in possession of any non-public information with respect to the Company. If by the twentieth Trading Day following delivery of the Subsequent Financing Notice no public announcement has been made, and no notice of the abandonment of such
Subsequent Financing has been received by the Purchasers, then the Purchasers shall assume that such Subsequent Financing has been abandoned and that the Purchasers are no longer in possession of any non-public information with respect to the
Company. 
 (f) The Company must provide the Purchasers with a second Subsequent Financing Notice, and the Purchasers will
again have the right of participation set forth above in this Section 4.12, if the Subsequent Financing subject to the initial Subsequent Financing Notice is not consummated for any reason substantially on the terms set forth in such Subsequent
Financing Notice within 20 Trading Days after the date of the initial Subsequent Financing Notice. 
 (g) Notwithstanding the
foregoing, this Section 4.12 shall not apply in respect of (i) an Exempt Issuance or (ii) a firm commitment underwritten public offering resulting in gross proceeds to the Company of in excess of $15,000,000, which shall not include
equity lines or similar transactions. 
  

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 4.13 Short Sales and Confidentiality After The Date Hereof. Each Purchaser severally and not
jointly with the other Purchasers covenants that neither it nor any Affiliate acting on its behalf or pursuant to any understanding with it will execute any Short Sales during the period commencing at the Discussion Time and ending on the one year
anniversary of the Closing Date. Each Purchaser, severally and not jointly with the other Purchasers, covenants that until such time as the transactions contemplated by this Agreement are publicly disclosed by the Company as described in
Section 4.4, such Purchaser will maintain the confidentiality of all disclosures made to it in connection with this transaction (including the existence and terms of this transaction). 
 4.14 Form D; Blue Sky Filings. The Company agrees to timely file a Form D with respect to the Securities as required under Regulation D and to
provide a copy thereof, promptly upon request of any Purchaser. The Company shall take such action as the Company shall reasonably determine is necessary in order to obtain an exemption for, or to qualify the Securities for, sale to the Purchasers
at the Closing under applicable securities or “Blue Sky” laws of the states of the United States, and shall provide evidence of such actions promptly upon request of any Purchaser. 
 4.15 Subsequent Equity Sales. 
 (a) From the date hereof until 90 days after the Effective Date, neither the Company nor any Subsidiary shall issue or enter into a contract to issue shares of Common Stock or Common Stock Equivalents; provided, however, the 90 day period
set forth in this Section 4.15 shall be extended (prior to the expiration thereof) for the number of Trading Days during such period in which (i) trading in the Common Stock is suspended by any Trading Market, or (ii) following the
Effective Date, the Registration Statement is not effective or the prospectus included in the Registration Statement may not be used by the Purchasers for the resale of the Shares and Warrant Shares. 
 (b) While the Notes are outstanding, the Company shall not issue any “Future Priced Securities” as such term is described
by NASD IM-4350-1. 
 (c) Notwithstanding the foregoing, this Section 4.15 shall not apply in respect of an Exempt
Issuance, except that no issuance of “Future Priced Securities” shall be an Exempt Issuance. 
 4.16 Subsequent
Registrations. Other than pursuant to the Registration Statement, prior to the Effective Date of a Registration Statement registering the resale by the Purchasers of the Warrant Shares, the Company may not file any registration statement with
the Commission (excluding amendments to existing registration statements) with respect to any securities of the Company other than registration statements on Form S-8 promulgated by the Commission. 
 4.17 Asset Sales. In the event the Company sells assets, including intellectual property or Intellectual Property Rights, outside of the ordinary
course of its business, at the election of the Required Purchasers, 50% of the net proceeds of any such sale shall be used to pay, on a pro rata basis, amounts owed to the Purchasers in respect of the Notes. Such net proceeds shall first be applied
to accrued but unpaid interest, and then to the principal amount due under the Notes. 

  

 34 

 
Within one Trading Day following any such sale, the Company must notify the Purchasers of any such asset sales, and file a Current Report on Form 8-K with
respect to such asset sales. 
 4.18 Future Guarantors. If any Subsidiary (other than a Subsidiary that is a party to the Guarantee
Agreement) is hereafter formed or acquired, the Company will notify the Purchasers in writing thereof not later than the tenth Trading Day after the date on which such Subsidiary is formed or acquired and the Company will cause such Subsidiary to
execute and deliver the Guarantee Agreement and all further agreements required by the Company in order to effectuate the transactions contemplated by the Transaction Documents in the manner provided therein, all at the expense of the Company, in
each case not later than the tenth Trading Day after the date on which such Subsidiary is formed or acquired (it being understood that all obligations and restrictions contained in the Transaction Documents as to any Subsidiaries, shall apply as of
the date of formation or acquisition of such Subsidiary). 
 ARTICLE V. 
 NEGATIVE COVENANTS 
 The Company and each Subsidiary hereby agrees that, from and after
the date hereof until the date that the Notes have either been repaid in their entirety and/or converted entirely into Common Stock, the Company and each Subsidiary shall be bound according to the restrictions set forth in each of the following
negative covenants unless any such restriction shall have been expressly waived in writing by the Required Purchasers: 
 5.1 Restrictions
on Certain Amendments. The Company will not amend the rights and privileges granted under the Notes, to adversely affect the rights or privileges granted under the Notes. 
 5.2 Restricted Payment. Neither the Company nor any Subsidiary shall make any Restricted Payment. 
 5.3 Indebtedness. Neither the Company nor any Subsidiary shall create, incur, assume, become or be liable in any manner in respect of, or suffer
to exist, any Indebtedness, except (a) Indebtedness in existence on the date hereof, as shown on Schedule 5.3(a), (b) trade payables incurred and paid in the ordinary course of business, (c) purchase money indebtedness for
assets acquired in the ordinary course of business, and (d) Contingent Liabilities in existence on the date hereof, as shown on Schedule 5.3(c) (collectively (a) through (d) shall be referred to as “Permitted
Indebtedness”). 
 5.4 Liens. Neither the Company nor any Subsidiary shall create or suffer to exist any Lien upon any of its
properties, except (a) Liens in existence on the date hereof and disclosed in Schedule 3.1(o), (b) tax, mechanics’, materialmen’s, warehousemen’s, laborer’s and landlord and other similar Liens relating to
amounts that are not yet due and payable, or that are being contested in good faith by appropriate proceedings, for which adequate reserves have been established, (c) Liens incurred in the ordinary course of business in connection with
worker’s compensation, unemployment insurance or similar legislation and (d) Liens to secure Permitted Indebtedness. Except as provided in this Section 5.4, neither the Company nor any Subsidiary 

  

 35 

 
shall hereafter agree with any Person (other than the Purchasers) to grant a Lien on any of its assets or to permit the pledge of any of its equity
interests. 
 5.5 Amendment of Organizational Documents. Neither the Company nor any Subsidiary shall permit any amendment to its
articles of incorporation so as to adversely affect the rights or privileges granted under the Notes. 
 5.6 Sale and Leaseback.
Neither the Company nor any Subsidiary shall enter into any arrangement whereby it sells or transfers any of its assets, and thereafter rents or leases such assets. 
 5.7 Business. The Company shall not change the primary focus of its business on health care products. 
 5.8 Transactions with Affiliates. Neither the Company nor any Subsidiary shall, directly or indirectly, pay any funds to or for the account of, make any investment (whether by acquisition of stock or indebtedness, by loan, advance,
transfer of property, guarantee or other agreement to pay, purchase or service, directly or indirectly, any Indebtedness, or otherwise) in, lease, sell, transfer or otherwise dispose of any assets, tangible or intangible, to, or participate in, or
effect any transaction in connection with any joint enterprise or other joint arrangement with, any Affiliate, except, on terms no less favorable than terms that could be obtained by the Company from a Person that is not an Affiliate of the Company
upon negotiation at arms’ length, as determined in good faith by the Board. 
 5.9 Limitation on Restrictions. Other than as
permitted by the Transaction Documents, the Company shall not, and shall not permit any Subsidiary, to enter into, or suffer to exist, any agreement with any Person which prohibits or limits its ability to (a) pay Indebtedness owed to the
Purchasers and (b) make loans or advances to the Company, pay dividends or other distributions in respect of its equity interests to the Company (except that Subsidiaries may pay dividends or other distributions) or guarantee Indebtedness of
the Company. 
 5.10 Payment of Cash Dividend. The Company and each Subsidiary agrees, so long as any of the Notes are outstanding,
not to declare, pay or make any provision for any cash dividend or distribution with respect to the Common Stock of the Company or each Subsidiary, as applicable. 
 5.11 Stock Repurchases. The Company agrees, so long as any of the Notes are outstanding, not to redeem any Common Stock or Common Stock Equivalents. 
 5.12 Investments, Loans, Advances and Guarantees. The Company will not, and will not permit any of the Subsidiaries to make or permit to exist any
loans or advances to, make or permit to exist any guarantees of any obligations of, or make or permit to exist any investment or any other interest in, any other Person, except: 
 (a) Permitted Investments; 
 (b) investments existing on the date hereof and set forth in Schedules 5.12(b); 
  

 36 

 (c) investments made by the Company in the equity interests of any Guarantor and made by
any Guarantor in the equity interests of any other Guarantor; and 
 (d) loans or advances made by the Company to any
Guarantor and made by any Guarantor to the Company or any Guarantor. 
 ARTICLE VI. 
 MISCELLANEOUS 
 6.1 Termination. This Agreement may be terminated prior to
the Closing: 
 (a) by written agreement of the Purchasers and the Company; 
 (b) by the Company or a Purchaser (as to itself but no other Purchaser) upon written notice to the other, if the Closing shall not have
taken place by 5:30 p.m. (New York City time) on the Outside Date; provided, that the right to terminate this Agreement under this Section 6.1(b) shall not be available to any Person whose failure to comply with its obligations under
this Agreement has been the cause of or resulted in the failure of the Closing to occur on or before such time. 
 (c) by a
Purchaser (as to itself but no other Purchaser) if it concludes in good faith that any of the conditions precedent contained in Sections 2.3(b)(iv), (v), (vi), or (vii) shall have been breached or shall not be capable of being satisfied by the
Outside Date despite the assumed best efforts of the Company. 
 In the event of a termination pursuant to this Section, the Company shall promptly notify
all non-terminating Purchasers. The Company and the terminating Purchaser(s) shall not have any further obligation or liability (including as arising from such termination) to the other and no Purchaser will have any liability to any other under the
Transaction Documents as a result therefrom. 
 6.2 Fees and Expenses. At the Closing, the Company shall pay to Bryan Cave LLP $35,000
(minus any amounts previously delivered) as partial reimbursement of SF Capital Partners Ltd. for its respective legal fees in connection with the Transaction Documents (SF Capital Partners Ltd. may deduct such amount from its Subscription Amount
deliverable to the Company at Closing), it being understood that Bryan Cave LLP has only rendered legal advice to SF Capital Partners Ltd., and not to the Company or any other Purchaser in connection with the transactions contemplated hereby, and
that each of the Company and the other Purchasers has relied for such matters on the advice of its own respective counsel. Except as specified in the immediately preceding sentence, each party shall pay the fees and expenses of its advisers,
counsel, accountants and other experts, if any, and all other expenses incurred by such party incident to the negotiation, preparation, execution, delivery and performance of the Transaction Documents. The Company shall pay all stamp and other taxes
and duties levied in connection with the sale of the Notes. 
 6.3 Entire Agreement. The Transaction Documents, together with the
exhibits and schedules thereto, contain the entire understanding of the parties with respect to the subject matter hereof and supersede all prior agreements and understandings, oral or written, with respect to such matters, which the parties
acknowledge have been merged into such documents, exhibits and schedules. 
  

 37 

 6.4 Notices. Any and all notices or other communications or deliveries required or permitted to be
provided hereunder shall be in writing and shall be deemed given and effective on the earliest of (a) the date of transmission, if such notice or communication is delivered via facsimile at the facsimile number set forth on the signature pages
attached hereto prior to 5:30 p.m. (New York City time) on a Trading Day, (b) the next Trading Day after the date of transmission, if such notice or communication is delivered via facsimile at the facsimile number set forth on the signature
pages attached hereto on a day that is not a Trading Day or later than 5:30 p.m. (New York City time) on any Trading Day, (c) the 2nd Trading Day following the date of mailing, if sent by U.S. nationally recognized overnight courier service, or (d) upon actual receipt by the party to whom such notice is required to be given. The address for such
notices and communications shall be as set forth on the signature pages attached hereto. 
 6.5 Amendments; Waivers. No provision of
this Agreement may be waived or amended except in a written instrument signed, in the case of an amendment, by the Company and the Required Purchasers. No waiver of any default with respect to any provision, condition or requirement of this
Agreement shall be deemed to be a continuing waiver in the future or a waiver of any subsequent default or a waiver of any other provision, condition or requirement hereof, nor shall any delay or omission of any party to exercise any right hereunder
in any manner impair the exercise of any such right. 
 6.6 Headings. The headings herein are for convenience only, do not constitute
a part of this Agreement and shall not be deemed to limit or affect any of the provisions hereof. 
 6.7 Successors and Assigns. This
Agreement shall be binding upon and inure to the benefit of the parties and their successors and permitted assigns. The Company may not assign this Agreement or any rights or obligations hereunder without the prior written consent of each Purchaser
(other than by merger). Any Purchaser may assign any or all of its rights under this Agreement to any Person to whom such Purchaser assigns or transfers any Securities, provided such transferee agrees in writing to be bound, with respect to the
transferred Securities, by the provisions of the Transaction Documents that apply to the “Purchasers”. 
 6.8 No
Third-Party Beneficiaries. This Agreement is intended for the benefit of the parties hereto and their respective successors and permitted assigns and is not for the benefit of, nor may any provision hereof be enforced by, any other Person,
except as otherwise set forth in Section 4.9. 
 6.9 Governing Law. All questions concerning the construction, validity,
enforcement and interpretation of this Agreement shall be governed by and construed and enforced in accordance with the internal laws of the State of New York, without regard to the principles of conflicts of law thereof. Each party agrees that all
Actions concerning the interpretations, enforcement and defense of the transactions contemplated by this Agreement and any other Transaction Documents (whether brought against a party hereto or its respective Affiliates, employees or agents) shall
be commenced exclusively in the New York Courts. Each party hereto hereby irrevocably submits to the exclusive jurisdiction of the New York Courts for the 

  

 38 

 
adjudication of any dispute hereunder or in connection herewith or with any transaction contemplated hereby or discussed herein (including with respect to
the enforcement of the any of the Transaction Documents), and hereby irrevocably waives, and agrees not to assert in any Action, any claim that it is not personally subject to the jurisdiction of any such New York Court, or that such Action has been
commenced in an improper or inconvenient forum. Each party hereto hereby irrevocably waives personal service of process and consents to process being served in any such Action by mailing a copy thereof via registered or certified mail or overnight
delivery (with evidence of delivery) to such party at the address in effect for notices to it under this Agreement and agrees that such service shall constitute good and sufficient service of process and notice thereof. Nothing contained herein
shall be deemed to limit in any way any right to serve process in any manner permitted by law. Each party hereto hereby irrevocably waives, to the fullest extent permitted by applicable law, any and all right to trial by jury in any legal proceeding
arising out of or relating to this Agreement or the transactions contemplated hereby. If either party shall commence an Action to enforce any provisions of a Transaction Document, then the prevailing party in such Action shall be reimbursed by the
other party for its reasonable attorneys’ fees and other costs and expenses incurred with the investigation, preparation and prosecution of such Action. 
 6.10 Survival. The representations and warranties contained herein shall survive the Closing and the delivery of the Shares and Warrant Shares. 
 6.11 Execution. This Agreement may be executed in two or more counterparts, all of which when taken together shall be considered one and the same
agreement and shall become effective when counterparts have been signed by each party and delivered to the other party, it being understood that both parties need not sign the same counterpart. In the event that any signature is delivered by
facsimile transmission or by e-mail delivery of a “.pdf” format data file, such signature shall create a valid and binding obligation of the party executing (or on whose behalf such signature is executed) with the same force and effect as
if such facsimile or “.pdf” signature page were an original thereof. 
 6.12 Severability. If any term, provision, covenant
or restriction of this Agreement is held by a court of competent jurisdiction to be invalid, illegal, void or unenforceable, the remainder of the terms, provisions, covenants and restrictions set forth herein shall remain in full force and effect
and shall in no way be affected, impaired or invalidated, and the parties hereto shall use their commercially reasonable efforts to find and employ an alternative means to achieve the same or substantially the same result as that contemplated by
such term, provision, covenant or restriction. It is hereby stipulated and declared to be the intention of the parties that they would have executed the remaining terms, provisions, covenants and restrictions without including any of such that may
be hereafter declared invalid, illegal, void or unenforceable. 
 6.13 Replacement of Securities. If any certificate or instrument
evidencing any Securities is mutilated, lost, stolen or destroyed, the Company shall issue or cause to be issued in exchange and substitution for and upon cancellation thereof (in the case of mutilation), or in lieu of and substitution therefor, a
new certificate or instrument, but only upon receipt of evidence reasonably satisfactory to the Company of such loss, theft or destruction. The applicant for a new certificate or instrument under such circumstances shall also pay any reasonable
third-party costs (including customary indemnity) associated with the issuance of such replacement Securities. 
  

 39 

 6.14 Remedies. In addition to being entitled to exercise all rights provided herein or granted by
law, including recovery of damages, each of the Purchasers and the Company will be entitled to specific performance under the Transaction Documents. The parties agree that monetary damages may not be adequate compensation for any loss incurred by
reason of any breach of obligations contained in the Transaction Documents and hereby agrees to waive and not to assert in any action for specific performance of any such obligation the defense that a remedy at law would be adequate. 
 6.15 Payment Set Aside. To the extent that the Company makes a payment or payments to any Purchaser pursuant to any Transaction Document or a
Purchaser enforces or exercises its rights thereunder, and such payment or payments or the proceeds of such enforcement or exercise or any part thereof are subsequently invalidated, declared to be fraudulent or preferential, set aside, recovered
from, disgorged by or are required to be refunded, repaid or otherwise restored to the Company, a trustee, receiver or any other person under any law (including, without limitation, any bankruptcy law, state or federal law, common law or equitable
cause of action), then to the extent of any such restoration the obligation or part thereof originally intended to be satisfied shall be revived and continued in full force and effect as if such payment had not been made or such enforcement or
setoff had not occurred. 
 6.16 Independent Nature of Purchasers’ Obligations and Rights. The obligations of each Purchaser
under any Transaction Document are several and not joint with the obligations of any other Purchaser, and no Purchaser shall be responsible in any way for the performance or non-performance of the obligations of any other Purchaser under any
Transaction Document. Nothing contained herein or in any other Transaction Document, and no action taken by any Purchaser pursuant thereto, shall be deemed to constitute the Purchasers as a partnership, an association, a joint venture or any other
kind of entity, or create a presumption that the Purchasers are in any way acting in concert or as a group with respect to such obligations or the transactions contemplated by the Transaction Documents. Each Purchaser shall be entitled to
independently protect and enforce its rights, including without limitation, the rights arising out of this Agreement or out of the other Transaction Documents, and it shall not be necessary for any other Purchaser to be joined as an additional party
in any proceeding for such purpose. Each Purchaser has been represented by its own separate legal counsel in their review and negotiation of the Transaction Documents. For reasons of administrative convenience only, Purchasers and their respective
counsel have chosen to communicate with the Company through Purchasers’ Counsel. Purchasers’ Counsel does not represent all of the Purchasers but only the Manager. The Company has elected to provide all Purchasers with the same terms and
Transaction Documents for the convenience of the Company and not because it was required or requested to do so by the Purchasers. 
 6.17
Limitation of Liability. Notwithstanding anything herein to the contrary, the Company acknowledges and agrees that the liability of a Purchaser arising directly or indirectly, under any Transaction Document of any and every nature whatsoever
shall be satisfied solely out of the assets of such Purchaser, and that no trustee, officer, other investment vehicle or any other 

  

 40 

 
Affiliate of such Purchaser or any investor, shareholder or holder of shares of beneficial interest of such a Purchaser shall be personally liable for any
liabilities of such Purchaser. 
 6.18 Liquidated Damages. The Company’s obligations to pay any partial liquidated damages or
other amounts owing under the Transaction Documents is a continuing obligation of the Company and shall not terminate until all unpaid partial liquidated damages and other amounts have been paid notwithstanding the fact that the instrument or
security pursuant to which such partial liquidated damages or other amounts are due and payable shall have been canceled. 
 6.19
Construction. The parties agree that each of them and/or their respective counsel has reviewed and had an opportunity to revise the Transaction Documents and, therefore, the normal rule of construction to the effect that any ambiguities are
to be resolved against the drafting party shall not be employed in the interpretation of the Transaction Documents or any amendments hereto. 
 (Signature Pages Follow) 
  

 41 

 IN WITNESS WHEREOF, the parties hereto have caused this Securities Purchase Agreement to be duly executed
by their respective authorized signatories as of the date first indicated above. 
  

									
	SYNOVA HEALTHCARE GROUP, INC.	 		 	Address for Notice:
				
	By:	 	  	 		 	1400 North Providence Road—Suite
		 	Name:	 		 	6010
		 	Title:	 		 	Media, PA 19063
		 		 		 	Attention: Stephen King

 With a copy to (which shall not constitute notice): 
 Alan L. Zeiger, Esq. 
 Blank Rome LLP 
 One Logan Square 
 Philadelphia, PA 19103-6998 
 [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK] 
  

 42 

 IN WITNESS WHEREOF, the parties hereto have caused this Securities Purchase Agreement to be duly executed
by their respective authorized signatories as of the date first indicated above. 
  

									
	SYNOVA HEALTHCARE, INC.	 		 	Address for Notice:
				
	By:	 	  	 		 	1400 North Providence Road—Suite 6010
		 	Name:	 		 	Media, PA 19063
		 	Title:	 		 	Attention: Stephen King

 With a copy to (which shall not constitute notice): 
 Alan L. Zeiger, Esq. 
 Blank Rome LLP 
 One Logan Square 
 Philadelphia, PA 19103-6998 
 [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK] 
  

 43 

 IN WITNESS WHEREOF, the parties hereto have caused this Securities Purchase Agreement to be duly executed
by their respective authorized signatories as of the date first indicated above. 
  

									
	SYNOVA PRE-NATAL HEALTHCARE, INC.	 		 	Address for Notice:
				
	By:	 	  	 		 	1400 North Providence Road—Suite 6010
		 	Name:	 		 	Media, PA 19063
		 	Title:	 		 	Attention: Stephen King

 With a copy to (which shall not constitute notice): 
 Alan L. Zeiger, Esq. 
 Blank Rome LLP 
 One Logan Square 
 Philadelphia, PA 19103-6998 
 [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK] 
  

 44 

 [PURCHASER SIGNATURE PAGES TO SYNOVA SECURITIES PURCHASE AGREEMENT] 
 IN WITNESS WHEREOF, the undersigned have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories as of
the date first indicated above. 
 Name of Purchaser:                                  
                                        
                                        
                                        
                                        
                          
 Signature of Authorized Signatory of Purchaser:                         
                                        
                                        
                                        
                    
 Name of Authorized Signatory:                               
                                        
                                        
                                        
                                        
      
 Title of Authorized Signatory:                               
                                        
                                        
                                        
                                        
         
 Email Address of Purchaser:                               
                                        
                                        
                                        
                                        
            
 Fax Number of Purchaser:                                
                                        
                                        
                                        
                                        
               
 Address for Notice of Purchaser: 
 Address for Delivery of Securities for Purchaser (if not same as above): 
 Subscription Amount: 
 Principal Amount of Notes: 
 Warrant Shares: 
 EIN Number: [PROVIDED UNDER SEPARATE COVER] 
  

 45

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