Document:

Amendment to the Asset Purchase Agreement

 Exhibit 10.15 
 Purchase Price Adjustment Side Letter 
 AzstaZeneca UK Limited 
 15 Stanhope Gate 
 London W1K 1LN, England

 June 28, 2006 
 Abraxis Bioscience. Inc.

 11777 San Vicente Boulevard, #500 
 Los Angeles, California
90049 
  

	 	Re:	Asset Purchase Agreement between AstraZeneca UK Limited (“AZ”) and Abraxis Bioscience, Inc. (“ABBI”) dated April 26, 2006 (the “Agreement”)

 Ladies and Gentlemen: 
 In connection with the
above-referenced Agreement, we are writing to confirm our understanding with respect to the matters set forth in this letter. Capitalized terms used, but not defined herein, shall have the meaning given to them in the Agreement. 
 AZ and ABBI hereby agree that the Purchase Price payable pursuant to Section 2.6 of the Agreement shall be adjusted as follows: 
 (a) Reduced by ten million dollars ($10,000,000), in consideration of which ABBI hereby agrees that the Approvals delivered by AZ at Closing pursuant to
Section 8.4 of the Agreement are reasonably satisfactory to ABBI; and 
 (b) Reduced by five million eight hundred thousand dollars
($5,800,000), which shall be in full satisfaction of AZ’s obligation under Section 2.4(b) of the Manufacturing and Supply Agreements to supply ABBI not less than a nine-week supply of Diprivan (together, the “Purchase Price
Adjustments”). 
 The Purchase Price Adjustments shall be made to the portion of the Purchase Price due and payable on the Closing Date pursuant to
Section 2.6(i) of the Agreement, and, as a result, the total amount due and payable by ABBI on the Closing Date shall be two hundred fifty nine million two hundred thousand dollars ($259,200,000). 
 This letter may be executed in one or more counterparts, each of which shall be deemed an original, but all of which, when taken together, shall constitute one and the
same instrument. This letter and the legal relations among the parties hereto shall be governed by and construed in accordance with the internal laws of the State of New York, without giving effect to the conflicts of laws principles thereof. This
letter and all of the terms and provisions hereof shall be binding upon and inure to the benefit of the parties hereto and their respective successors and permitted assigns, and neither this letter nor any of the rights, interests or obligations
hereunder of the parties hereto may be assigned by any of the parties hereto without the prior written consent of the other party. 

 Purchase Price Adjustment Side Letter 
 Please indicate your agreement with the foregoing by countersigning this letter where indicated below. 
  

			
	ASTRAZENECA UK LIMITED
		
	By:	 	/s/ Russell Gannt
	Name:	 	Russell Gannt
	Title:	 	Authorized Person

 AGREED: 
  

			
	ABRAXIS BIOSCIENCE, INC.
		
	By:	 	/s/ Bruce Wendel
	Name:	 	Bruce Wendel
	Title:	 	Executive Vice President Corporate DevelopmentAgreement between Registrant and RSU LLC

 Exhibit 10.16 
 AGREEMENT 
 This AGREEMENT (this “Agreement”) is made and entered into as of April 18, 2006, by
and between Abraxis BioScience, Inc. f/k/a American Pharmaceutical Partners, Inc., a Delaware corporation (the “Company”), and RSU Plan LLC (“RSU LLC”). 
 WHEREAS, American BioScience, Inc., a California corporation (“ABI”), and the Company have entered into an Agreement and Plan of Merger,
dated as of November 27, 2005 (as it may be amended from time to time, the “Merger Agreement”), pursuant to which, at the “Effective Time” (as defined in the Merger Agreement), ABI will merge with and into the
Company (the “Merger”); 
 WHEREAS, ABI has adopted the American BioScience, Inc. Restricted Stock Unit Plan II (the
“Plan”) pursuant to which Restricted Stock Units have been granted to Employees of the Company and its Affiliates; 
 WHEREAS, following the Effective Time, on the occurrence of Vesting Dates specified in award agreements issued pursuant to the Plan, holders of Restricted Stock Units will become entitled to receive shares of common stock of the Company
(“ABBI Common Stock”) equal in value to the value of the Restricted Stock Units based on the then-current market price of ABBI Common Stock or cash (or a combination thereof); and 
 WHEREAS, the Company and RSU LLC intend hereby to provide that (i) prior to each date on which Restricted Stock Units are settled under the Plan by
reason of the occurrence of a Vesting Date (each such date, a “Settlement Date”), RSU LLC shall deliver, or cause to be delivered, to the Company shares of ABBI Common Stock or cash (or a combination thereof) in an amount sufficient
to satisfy the obligations of the Company to Participants in respect of Restricted Stock Units that have become vested on such Vesting Date, and (ii) the Company shall satisfy its obligations under the Plan by paying the Participants cash
and/or shares of ABBI Common Stock in the same proportion as such delivery by RSU LLC; 
 NOW THEREFORE, in consideration of the mutual
covenants and agreements contained herein, and intending to be legally bound, the parties agree as follows: 
 1. Delivery by RSU LLC.
RSU LLC hereby agrees that, on or prior to each Settlement Date, it shall deliver, or cause to be delivered, to the Company (i) shares of ABBI Common Stock, (ii) cash or (iii) a combination of shares of ABBI Common Stock and cash, in
each case in number and/or amount equal to the aggregate value of the vested Restricted Stock Units to be settled on such Settlement Date. For purposes of the preceding sentence, the value of any shares of ABBI Common Stock to be so delivered shall
be determined by reference to the valuation provisions set forth in the award agreements issued under the Plan. The Company shall give RSU LLC not less than ten business days’ notice of each Settlement Date. The decision by RSU LLC of whether
to deliver ABBI Common Stock, cash or a combination of ABBI Common Stock and cash in satisfaction of its obligations hereunder shall be made by RSU LLC in its sole discretion. 

 2. Satisfaction by the Company of its Obligations under the Plan. The Company hereby agrees as
follows: 
 (i) In the event that a delivery made by RSU LLC pursuant to Section 1 of this Agreement in respect of a
Settlement Date consists solely of shares of ABBI Common Stock, the Company shall settle the vested Restricted Stock Units to be settled on such Settlement Date by delivering solely ABBI Common Stock to the holders thereof. 
 (ii) In the event that a delivery made by RSU LLC pursuant to Section 1 of this Agreement in respect of a Settlement Date consists
solely of cash, the Company shall settle the vested Restricted Stock Units to be settled on such Settlement Date by delivering solely cash to the holders thereof. 
 (iii) In the event that a delivery made by RSU LLC pursuant to Section 1 of this Agreement in respect of a Settlement Date consists
of a combination of shares of ABBI Common Stock and cash, the Company shall settle the vested Restricted Stock Units to be settled on such Settlement Date by delivering to each holder thereof a number of shares of ABBI Common Stock and an amount of
cash in the same proportions as the proportions of ABBI Common Stock and cash so delivered by RSU LLC; provided, that the Company may, in its discretion, disproportionately withhold cash from a holder in satisfaction of its obligations to
withhold income and employment taxes in connection with the vesting of Restricted Stock Units. 
 3. Miscellaneous. 
 (a) Capitalized Terms. Capitalized terms used but not defined herein shall have the meanings set forth in the Plan or in the award
agreements issued under the Plan, as applicable. 
 (b) Effectiveness. This Agreement shall become effective at the
Effective Time and shall terminate without liability or penalty on the part of either party hereto upon termination of the Merger Agreement pursuant to the terms thereof. 
 (c) Notices. Unless otherwise provided herein, all notices, requests, demands, claims and other communications provided for under
the terms of this Agreement shall be in writing. Any notice, request, demand, claim or other communication hereunder shall be sent by (i) personal delivery (including receipted courier service) or overnight delivery service, (ii) facsimile
during normal business hours, with confirmation of receipt, to any facsimile number provided by either party hereto to the other party for purposes of receipt of notice, (iii) reputable commercial overnight delivery service courier or
(iv) registered or certified mail, return receipt requested, postage prepaid and addressed to the intended recipient as set forth below: 
 (i) If to RSU LLC, to: 
   RSU Plan LLC 
   149 South Barrington Ave., #311 
   Los Angeles, CA 90049 
   Attention: Manager 
  

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 (ii) If to the Company, to: 
   Abraxis BioScience, Inc. 
   11777 San Vicente Blvd., Suite 550 
   Los Angeles, CA 90049 
   Attention: General Counsel 
 All such notices,
requests, consents and other communications shall be deemed to have been given when received. Either party may change its facsimile number or its address to which notices, requests, demands, claims and other communications hereunder are to be
delivered by giving the other party hereto notice in the manner then set forth. 
 (d) Amendments. Except as otherwise
provided herein, no modification, amendment or waiver of any provision of this Agreement shall be effective against any party unless such modification, amendment or waiver is approved in writing by each party hereto. The failure of either party to
enforce any of the provisions of this Agreement shall in no way be construed as a waiver of such provisions and shall not affect the right of such party thereafter to enforce each and every provision of this Agreement in accordance with its terms.

 (e) Binding Effect. This Agreement shall be binding upon and inure to the benefit of both parties and their
successors, legal representatives and assigns. 
 (f) Severability. The invalidity or unenforceability of any
particular provision of this Agreement shall not affect the other provisions hereof, and this Agreement shall be construed in all respects as if such invalid or unenforceable provision were omitted. 
 (g) Counterparts. This Agreement may be executed in counterparts with the same effect as if the parties hereto had signed the same
document. All counterparts shall be construed together and shall constitute one instrument. 
 (h) No Third Party
Beneficiaries. No provision of this Agreement shall create or be deemed to create any third party beneficiary rights in any person not a party to this Agreement. 
 (i) Integration. This Agreement constitutes the entire agreement between the parties hereto pertaining to the subject matter hereof
and, except as otherwise provided herein, supersedes all prior agreements and understandings pertaining thereto. 
 (j)
Governing Law. This Agreement and the rights of the parties hereunder shall be interpreted in accordance with the laws of the State of Delaware, and all rights and remedies shall be governed by such laws without regard to principles of
conflict of laws. 
  

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 IN WITNESS WHEREOF, the parties to this Agreement have duly executed and delivered this Agreement as of
the date first written above. 
  

									
	 RSU PLAN LLC
	 		 	 ABRAXIS BIOSCIENCE, INC.

			
	/s/ Steve H. Hassan	 		 	 /s/ Richard E. Maroun

	 Name:
	 	Steve H. Hassan	 		 	 Name:
	 	Richard E. Maroun
	 Title:
	 	 Manager
	 		 	 Title:
	 	 CAO

  

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