Document:

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                    METLIFE INSURANCE COMPANY OF CONNECTICUT
                              1300 Hall Boulevard
                             Bloomfield, CT 06002

          ROTH INDIVIDUAL RETIREMENT ANNUITY ("ROTH IRA") ENDORSEMENT

The provisions in this Roth IRA Endorsement (the "Endorsement") are effective as
of the issue date for the attached annuity contract (the "Contract") as a Roth
IRA (or the date it has been converted to a Roth IRA), unless a later date is
specified under the federal tax law with respect to a provision hereunder.

The provisions below this paragraph, through Article VIII, of this Endorsement
are word-for-word identical to the operative provisions in Articles I through
VIII of IRS Form 5305-RB (dated March 2002) and are deemed to meet the statutory
requirements for a Roth IRA. These provisions are clarified in accordance with
more recent IRS guidance in Article IX below.

This Endorsement is made a part of the annuity contract to which it is attached,
and the following provisions apply in lieu of any provisions in the contract to
the contrary.

The annuitant is establishing a Roth Individual Retirement Annuity (Roth IRA)
under section 408A of the Internal Revenue Code to provide for his or her
retirement and for the support of his or her beneficiaries after death.

ARTICLE I

Except in the case of a rollover contribution described in section 408A(e), a
re-characterized contribution described in section 408A(d)(6), or an IRA
Conversion Contribution, the issuer will accept only cash contributions up to
$3,000 per year for tax years 2002 through 2004. That contribution limit is
increased to $4,000 for tax years 2005 through 2007 and $5,000 for 2008 and
thereafter. For individuals who have reached the age of 50 before the close of
the tax year, the contribution limit is increased to $3,500 per year for tax
years 2002 through 2004, $4,500 for 2005, $5,000 for 2006 and 2007, and $6,000
for 2008 and thereafter. For tax years after 2008, the above limits will be
increased to reflect a cost-of-living adjustment, if any.

ARTICLE II

     1.   The contribution limit described in Article I is gradually reduced to
          $0 for higher income annuitants. For a single annuitant, the annual
          contribution is phased out between adjusted gross income (AGI) of
          $95,000 and $110,000; for a married annuitant filing jointly, between
          AGI of $150,000 and $160,000; and for a married annuitant filing
          separately, between AGI of $0 and $10,000. In the case of a
          conversion, the issuer will not accept IRA Conversion Contributions in
          a tax year if the annuitant's AGI for the tax year the funds were
          distributed from the other IRA exceeds $100,000 or if the annuitant is
          married and files a separate return. Adjusted gross income is defined
          in section 408A(c)(3) and does not include IRA Conversion
          Contributions.

     2.   In the case of a joint return, the AGI limits in the preceding
          paragraph apply to the combined AGI of the annuitant and his or her
          spouse

ARTICLE III

The annuitant's interest in the contract is nonforfeitable and nontransferable.

ARTICLE IV

     1.   The contract does not require fixed contributions.

     2.   Any dividends (refund of contributions other than those attributable
          to excess contributions) arising under the contract will be applied
          (before the close of the calendar year following the year of the
          dividend) as contributions toward the contract.

ARTICLE V

     1.   If the annuitant dies before his or her entire interest in the
          contract is distributed to him or her and the annuitant's surviving
          spouse is not the designated beneficiary, the remaining interest in
          the contract will be distributed in accordance with (a) below or, if
          elected or there is no designated beneficiary, in accordance with (b)
          below:

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          (a)  The remaining interest in the contract will be distributed,
               starting by the end of the calendar year following the year of
               the annuitant's death, over the designated beneficiary's
               remaining life expectancy, or a period no longer than such
               remaining life expectancy, as determined in the year following
               the death of the annuitant. Life expectancy is determined using
               the single life table in Regulations section 1.401(a)(9)-9.

          (b)  The remaining interest in the contract will be distributed by
               the end of the calendar year containing the fifth anniversary of
               the annuitant's death.

     2.   If the annuitant's surviving spouse is the designated beneficiary,
          such spouse will then be treated as the annuitant.

ARTICLE VI

     1.   The annuitant agrees to provide the issuer with all information
          necessary to prepare any reports required by sections 408(i) and
          408A(d)(3)(E), Regulations sections 1.408-5 and 1.408-6, or other
          guidance published by the Internal Revenue Service (IRS).

     2.   The issuer agrees to submit to the IRS and annuitant the reports
          prescribed by the IRS.

ARTICLE VII

Notwithstanding any other articles which may be added or incorporated, the
provisions of Articles I through IV and this sentence will be controlling. Any
additional articles inconsistent with section 408A, the related regulations, or
other published guidance will be invalid.

ARTICLE VIII

This Endorsement will be amended as necessary to comply with the provisions of
the Code, the related regulations, and other published guidance. Other
amendments may be made with the consent of the persons whose signatures appear
on the contract.

ARTICLE IX

A.   Clarifications of Terms Used in This Endorsement
     ------------------------------------------------

     1.   The term "issuer," "we" or "us" means MetLife Insurance Company of
          Connecticut.

     2.   The term "annuitant," "you" or "your" refers to the individual who is
          the measuring life, as well as the individual owner (or "owner"),
          under this Contract. The term "Contract" also may refer to a
          certificate issued under a group annuity contract. No joint owner or
          contingent annuitant may be named under this Contract. If this is an
          inherited IRA within the meaning of Code Section 408(d)(3)(c)
          maintained for the benefit of a designated beneficiary of a deceased
          individual, references in this document to "annuitant," "owner," "you"
          or "your" are to the deceased individual.

     3.   The term "article" as used in Article VII may include any provision
          of the Contract (including any rider or endorsement).

B.   Clarifications of Articles I-VIII and Other Contract Provisions
     ---------------------------------------------------------------

     1.   The Contract as modified by this Endorsement is intended to qualify
          as part of a tax-qualified retirement arrangement, plan or contract
          that meets the requirements of section 408A and any applicable
          Treasury Regulations, i.e., to qualify as a Roth IRA. To achieve these
          purposes, the provisions of this Endorsement shall control if they are
          in conflict with those of the Contract, and the provisions of this
          Endorsement and the Contract (including any other rider or endorsement
          that does not specifically override this provision) shall be
          interpreted to ensure or maintain such tax qualification, despite any
          other provision to the contrary. Payments and distributions under this
          Contract shall be made in a time and manner necessary to maintain such
          a tax qualification under the applicable provisions of the Internal
          Revenue Code (the "Code"). We reserve the right to amend this
          Endorsement or the Contract to comply with any applicable changes in
          the Code or any regulations or other published guidance relating
          thereto, or to reflect any clarifications that may be needed or are
          appropriate to maintain such tax qualification. We will send you a
          copy of any such amendment, and when required by law, we will obtain
          the approval of the appropriate regulatory authority or of the
          annuitant.

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2.   No benefits under the Contract may be transferred, sold, assigned,
     borrowed, or pledged as collateral for a loan, or as security for the
     performance of an obligation, or for any other purpose, to any person,
     except that the Contract may be transferred under a divorce or separation
     instrument described in section 408(d)(6).

3.   (a) Maximum Permissible Amount. Except in the case of a qualified rollover
     contribution, a nontaxable transfer from an individual retirement plan
     under Section 7701(a)(37) of the Code, or a recharacterization (as defined
     in (f) below), ongoing contributions to this Contract (if permitted) must
     be in cash and the total of such contributions to all the individual
     owner's Roth IRAs for a taxable year shall not exceed the applicable amount
     (as defined in (b) below), or the individual owner's compensation (as
     defined in (h) below), if less, for that taxable year (or such other amount
     provided by applicable federal tax law). Any contribution described in the
     previous sentence that may not exceed the lesser of the applicable amount
     or the individual owner's compensation is referred to as a "regular
     contribution." A "qualified rollover contribution" is a rollover
     contribution of a distribution from an eligible retirement plan described
     in section 402(c)(8)(B) (or such other amounts provided by applicable
     federal tax law). If the distribution is from an IRA, the rollover must
     meet the requirements of section 408(d)(3), except the
     one-rollover-per-year rule of section 408(d)(3)(B) does not apply if the
     rollover contribution is from an IRA other than a Roth IRA (a "nonRoth
     IRA"). If the rollover contribution is from an eligible retirement plan
     other than an IRA, the rollover must meet the requirements of section
     402(c), 402(e)(6), 403(a)(4), 403(b)(8), 403(b)(10), 408(d)(3) or
     457(e)(16), as applicable, Contributions may be limited under (c) through
     (e) below.

     (b)  Applicable Amount. The applicable amount is determined below:

          (i)  If the individual owner is under age 50, the applicable amount
               is $5,000 for any taxable year beginning in 2008 and years
               thereafter. After 2008, the $5,000 amount will be adjusted by the
               Secretary of the Treasury for cost-of-living increases under
               section 219(b)(5)(D). Such adjustments will be in multiples of
               $500.

          (ii) If the individual owner is 50 or older, the applicable amount
               under paragraph (i) above is increased by $1,000 for any taxable
               year beginning in 2006 and years thereafter.

     (c)  Regular Contribution Limit. The maximum regular contribution that can
          be made to all the individual owner's Roth IRAs for a taxable year is
          the smaller amount determined under (i) or (ii) below.

          (i)  The maximum regular contribution is phased out ratably between
               certain levels of modified adjusted gross income ("modified
               AGI"), as defined in (g) below, in accordance with the following
               table:

<TABLE>
<CAPTION>
               Filing Status                         Full Contribution   Phase-Out Range                No Contribution
               ------------------------------------  ------------------  -----------------------------  ---------------
                                                              Modified AGI
               --------------------------------------------------------------------------------------------------------
               <S>                                   <C>                 <C>                            <C>
               Single or Head of Household           $95,000 or less     Between $95,000 and $110,000   $ 110,000 or more
               Joint Return or Qualifying Widow(er)  $  150,000 or less  Between $150,000 and $160,000  $ 160,000 or more
               Married - Separate Return             $                0  Between $0 and $10,000         $ 10,000 or more
</TABLE>

If the individual owner's modified AGI for a taxable year is in the phase-out
range, the maximum regular contribution determined under this table for that
taxable year is rounded up to the next multiple of $10 and is not reduced below
$200. After 2006, the dollar amounts above will be adjusted by the Secretary of
the Treasury for cost-of-living increases under section 408A(c)(3). Such
adjustments will be in multiples of $1,000.

          (ii) If the individual owner makes regular contributions to both Roth
               and nonRoth IRAs for a taxable year, the maximum regular
               contribution that can be made to all such individual's Roth IRAs
               for that taxable year is reduced by the regular contributions
               made to such individual's nonRoth IRAs for the taxable year.

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          (d)  Inherited IRA. If this is an inherited IRA within the meaning of
               Code Section 408(d)(3)(c), no additional contributions will be
               accepted.

          (e)  SIMPLE IRA Limits. No contribution shall be allowed into this
               Contract under a SIMPLE IRA plan established by any employer
               pursuant to section 408(p). Also, no transfer or rollover of
               funds attributable to contributions made by a particular employer
               under its SIMPLE IRA plan shall be allowed into this Contract
               from a SIMPLE IRA, that is, an IRA used in conjunction with a
               SIMPLE IRA plan, prior to the expiration of the 2-year period
               beginning on the date the individual owner first participated in
               that employer's SIMPLE IRA plan.

          (f)  Recharacterization. A regular contribution to a nonRoth IRA may
               be recharacterized pursuant to the rules in Treas. Reg. Sec.
               1.408A-5 as a regular contribution to this Roth IRA (if
               permitted), subject to the limits in (c) above.

          (g)  Modified AGI. For purposes of (c) above, an individual owner's
               modified AGI for a taxable year is defined in section 408A(c)(3)
               and does not include any amount included in adjusted gross income
               as a result of a qualified rollover contribution (a
               "conversion").

          (h)  Compensation. For purposes of (a) above, compensation is defined
               as wages, salaries, professional fees, or other amounts derived
               from or received for personal services actually rendered
               (including, but not limited to commissions paid salesmen,
               compensation for services on the basis of a percentage of
               profits, commissions on insurance premiums, tips, and bonuses)
               and includes earned income, as defined in section 401(c)(2)
               (reduced by the deduction the self-employed individual owner
               takes for contributions made to a self-employed retirement plan).
               For purposes of this definition, section 401(c)(2) shall be
               applied as if the term trade or business for purposes of section
               1402 included service described in subsection (c)(6).
               Compensation does not include amounts derived from or received as
               earnings or profits from property (including but not limited to
               interest and dividends) or amounts not includible in gross income
               (determined without regard to Code Section 112). Compensation
               also does not include any amount received as a pension or annuity
               or as deferred compensation. The term "compensation" shall
               include any amount includible in the individual owner's gross
               income under section 71 with respect to a divorce or separation
               instrument described in subparagraph (A) of section 71(b)(2). In
               the case of a married individual filing a joint return, the
               greater compensation of his or her spouse is treated as his or
               her own compensation, but only to the extent that such spouse's
               compensation is not being used for purposes of the spouse making
               an IRA contribution. The term "compensation" also includes any
               differential wage payments as defined in Code Section 3401(h)(2).

               (i)  The owner shall have the sole responsibility for
                    determining whether any contribution satisfies applicable
                    income tax requirements.

     4.   No amount is required to be distributed prior to the death of the
          individual owner for whose benefit the Contract was originally
          established. If this is an inherited IRA within the meaning of the
          Code Section 408(d)(3)(C), this paragraph does not apply. However,
          prior to the time you reach the Maximum Annuity Date or maturity date
          under this contract (as the case may be), we will send you information
          about annuity payment options so that you may consider whether to
          continue the deferral of distributions under your Roth IRA contract
          provisions or begin to receive annuity payments or other withdrawals
          from your Contract.

     5.   (a)  Notwithstanding any provision of this Roth IRA Contract to
               the contrary, the distribution of the individual owner's interest
               in the Roth IRA shall be made in accordance with the requirements
               of section 408(b)(3), as modified by section 408A(c)(5), and the
               Treasury Regulations thereunder, the provisions of which are
               herein incorporated by this reference. If distributions are not
               made in the form of an annuity on an irrevocable basis (except
               for acceleration), then distribution of the interest in the Roth
               IRA (as determined under section 5(c), below) must satisfy the
               requirements of section 408(a)(6), as modified by section
               408A(c)(5) and the Treasury Regulations thereunder, rather than
               the distribution rules in paragraphs 5(b), (c), (d) and (e)
               below.

          (b)  Upon the death of the individual owner, his or her entire
               interest shall be distributed at least as rapidly as follows:

               (i)  If the designated beneficiary is someone other than
                    such individual's surviving spouse, the entire interest
                    shall be distributed, starting by the end of the calendar
                    year following the calendar year of such individual's death,
                    over the life of the designated beneficiary or over a period
                    not extending beyond the life expectancy of the designated
                    beneficiary, with such life expectancy determined using the
                    age of the beneficiary as of his or her birthday in the year
                    following the year of such individual's death, or, if
                    elected, in accordance with paragraph (b)(iii) below. If
                    this is an inherited IRA within the meaning of Code Section
                    408(d)(3)(C) established for the benefit of a non-spouse

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                         designated beneficiary by a direct trustee-to-trustee
                         transfer from a retirement plan of a deceased
                         individual under Sec. 402(c)(11), then, notwithstanding
                         any election made by the deceased individual, the
                         non-spouse designated beneficiary may elect to have
                         distributions made under this paragraph if the transfer
                         is made no later than the end of the year following the
                         year of death.

                   (ii)  If such individual's sole designated beneficiary is
                         such individual's surviving spouse, the entire interest
                         shall be distributed, starting by the end of the
                         calendar year following the calendar year of such
                         individual's death (or by the end of the calendar year
                         in which such individual would have attained age
                         70 1/2, if later), over such spouse's life or over a
                         period not extending beyond the life expectancy of the
                         surviving spouse, or, if elected, in accordance with
                         paragraph (b)(iii) below. If such surviving spouse dies
                         before required distributions commence to him or her,
                         the remaining interest shall be distributed, starting
                         by the end of the calendar year following the calendar
                         year of such spouse's death, over such spouse's
                         designated beneficiary's remaining life expectancy
                         determined using such beneficiary's age as of his or
                         her birthday in the year following the death of such
                         spouse, or, if elected, shall be distributed in
                         accordance with paragraph (b)(iii) below. If such
                         surviving spouse dies after required distributions
                         commence to him or her, any remaining interest shall
                         continue to be distributed under the contract option
                         chosen.

                  (iii)  If there is no designated beneficiary, or if applicable
                         by operation of paragraph (b)(i) or (b)(ii) above, the
                         entire interest shall be distributed by the end of the
                         calendar year containing the fifth anniversary of such
                         individual's death (or of the spouse's death in the
                         case of the surviving spouse's death before
                         distributions are required to begin under paragraph (b)
                         (ii) above).

                   (iv)  Life expectancy is determined using the Single Life
                         Table in Q&A-1 of Treas. Reg. Sec. 1.401(a)(9)-9. If
                         distributions are being made to a surviving spouse as
                         the sole designated beneficiary, such spouse's
                         remaining life expectancy for a year is the number in
                         the Single Life Table corresponding to such spouse's
                         age in the year. In all other cases, remaining life
                         expectancy for a year is the number in the Single Life
                         Table corresponding to the beneficiary's age in the
                         year specified in paragraph (b)(i) or (ii) and reduced
                         by 1 for each subsequent year.

          (c)  The "interest" in the Roth IRA includes the amount of any
               outstanding rollover, transfer and recharacterization under
               Q&As-7 and -8 of Treas. Reg. Sec. 1.408-8. Also, prior to the
               date that the Contract is annuitized, the "interest" in the
               Contract includes the actuarial present value of any additional
               benefits provided under this IRA Contract (such as survivor
               benefits in excess of the dollar amount credited to Your
               beneficiary under the Contract) under Q&A-12 of Section
               1.401(a)(9)-6 of the Income Tax Regulations.

          (d)  For purposes of paragraph 5(b)(ii) above, required distributions
               are considered to commence on the date distributions are required
               to begin to the surviving spouse under such paragraph. However,
               if distributions start prior to the applicable date in the
               preceding sentence, on an irrevocable basis (except for
               acceleration) under an annuity contract meeting the requirements
               of Treas. Reg. Sec. 1.401(a)(9)-6, then required distributions
               are considered to commence on the annuity starting date.

          (e)  If the sole designated beneficiary is the individual owner's
               surviving spouse, the spouse may elect to treat the Roth IRA as
               his or her own Roth IRA. This election shall be deemed to have
               been made if such surviving spouse makes a contribution to the
               Roth IRA or fails to take required distributions as a
               beneficiary.

          (f)  The required minimum distributions payable to a designated
               beneficiary from this Roth IRA may be withdrawn from another Roth
               IRA the beneficiary holds from the same decedent in accordance
               with Q&A-9 of Sec.1.408-8 of the Income Tax Regulations.

          (g)  The owner or the owner's beneficiary, as applicable, shall have
               the sole responsibility for requesting or arranging for
               distributions that comply with this Endorsement and applicable
               income tax requirements.

     6.   If your Contract contains any provisions relating to federal tax
          requirements for any Traditional, SEP or SIMPLE IRA contract that do
          not apply to Roth IRAs, they are hereby deleted by this Endorsement.
          This includes, but is not limited to, provisions relating to required
          minimum distribution ("RMD") requirements during your life that apply
          to any Traditional, SEP or SIMPLE IRA but do not apply to your Roth
          IRA, such as:

          (a)  Automatic sending of information about income plans when you
               attain age 70 or starting income payments on the April 1
               following the calendar year you attain age 70 1/2, or

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          (b)  Waiver of withdrawal charges on withdrawals required to avoid
               federal income tax penalties or to satisfy such pre-death RMD
               income tax rules.

               In addition, any references to unisex rates in the Annuity Table
               or the use of such rates for SEP or SIMPLE IRAs are deleted.

     7.   Notwithstanding Article IV above, no dividends are paid under this
          Contract.

     8.   If (a) no premiums have been received for two full consecutive
          contract years, (b) the account balance is less than $2,000, and (c)
          the paid-up annuity benefit at maturity or the Maximum Annuity Date
          would be less than $20 per month, we may choose either (i) to accept
          additional future premium payments under the Contract, or (ii) where
          otherwise permitted by law and the terms of the Contract, to terminate
          the Contract by a lump sum payment of the then present value of the
          paid-up benefit.

All other terms and conditions of the Contract remain unchanged.

MetLife Insurance Company of Connecticut has caused this Endorsement to be
signed by its Secretary

                                          [
                                             /s/ Isaac Torres
                                             -----------------------
                                                                 ]
                                          [SECRETARY]

L-22503 (09/12)                        6Agreement

 Exhibit 10.1 
 AGREEMENT 
 This Agreement (this “Agreement”), dated as of
December 5, 2012, is entered into by MEI Pharma, Inc. (formerly known as Marshall Edwards, Inc.), a Delaware corporation (“MEIP”), Novogen Limited, a public company limited by shares and incorporated under the
laws of New South Wales, Australia (“Seller Parent”), Novogen Research Pty Limited, a proprietary limited company incorporated under the laws of Australia and a wholly-owned subsidiary of Seller Parent
(“Seller” and together with Seller Parent, the “Novogen Parties” and each, a “Novogen Party”) and Graham Kelly, an individual, and Andrew Heaton, an individual, for purposes of
Section 4.2 and Articles VII and VIII, only. 
 RECITALS 

WHEREAS, pursuant to the Asset Purchase Agreement, dated as of December 21, 2010 (the “Asset Purchase
Agreement”), entered into by MEIP, Seller Parent and Seller, each Novogen Party agreed to the world-wide non-competition restrictions set forth in Section 5.4(d) of the Asset Purchase Agreement (the “Non-Compete
Provisions”); 
 WHEREAS, Seller Parent and Triaxial Pharmaceuticals Pty Ltd, a proprietary limited company
incorporated under the laws of Australia (“Triaxial”), entered into a term sheet, dated November 12, 2012, in relation to the acquisition of Triaxial by Seller Parent (the “Acquisition”); 

WHEREAS, Triaxial is engaged in, among other things, the development of certain products which, if engaged in by the
Novogen Parties, may be a violation of the Non-Compete Provisions; 
 WHEREAS, in anticipation of the Acquisition,
the Novogen Parties desire to obtain a limited waiver of the Non-Compete Provisions such that the Non-Compete Provisions will not apply to the Exploitation by any Novogen Party (or by any of their respective Affiliates) of Triaxial
Intellectual Property (as defined below) that does not infringe or otherwise violate the Intellectual Property rights of MEIP; and 
 WHEREAS, subject to the terms and conditions of this Agreement, MEIP is willing to grant a limited waiver of the Non-Compete Provisions. 

NOW, THEREFORE, in consideration of the mutual benefits to be derived from this Agreement and of the conditions and promises
contained herein and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto, intending to be legally bound, hereby agree as follows: 

ARTICLE I 

DEFINITIONS; INTERPRETATION 
 Section 1.1. Definitions. 
 Capitalized terms that are used but not
defined herein have the meanings given to them in the Asset Purchase Agreement. As used herein, the following terms have the following meanings: 
 “Acquisition” has the meaning set forth in the recitals hereof. 

 “Agreement” has the meaning set forth in the preamble hereof. 

“Asset Purchase Agreement” has the meaning set forth in the recitals hereof. 

“Cancellation Warrants” has the meaning set forth in Section 2.1. 

“Excluded Persons” means (i) Graham Kelly, an individual, (ii) Andrew Heaton, an individual,
(iii) any immediate family member of Graham Kelly or Andrew Heaton, (iv) any Affiliate or employee of Graham Kelly or Andrew Heaton, and (v) any Person that is a shareholder of Triaxial. 

“MEIP” has the meaning set forth in the preamble hereof. 

“MEIP Shares” means shares of MEIP common Stock, par value $0.00000002. 

“MEIP Warrants” means warrants issued to Seller Parent on May 14, 2012 purchase MEIP Shares. 

“Non-Compete Provisions” has the meaning set forth in the recitals hereof. 

“Seller” has the meaning set forth in the preamble hereof. 

“Seller Parent” has the meaning set forth in the preamble hereof. 

“Novogen Parties” has the meaning set forth in the preamble hereof. 

“Novogen Persons” means certain directors and officers of Novogen. 

“Proprietary Information” means all MEIP Intellectual Property and information that relates to the Purchased Assets or
the Exploitation of the Technology, and all notes, analyses, compilations, studies, summaries and other material to the extent containing or based, in whole or in part, upon any information that relates to the Purchased Assets or the Exploitation of
the Technology. 
 “Remaining MEIP Warrants” means all MEIP Warrants that are held by Seller Parent or any
Affiliate thereof or otherwise beneficially owned by Seller Parent other than the Cancellation Warrants. 

“Triaxial” has the meaning set forth in the recitals hereof. 

“Triaxial Intellectual Property” has the meaning set forth in Section 3.1. 

“Warrant Agent” has the meaning set forth in Section 2.1(a). 

  
 2 

 Section 1.2. Descriptive Headings; Certain Definitions. 

(a) Descriptive headings are for convenience only and shall not control or affect the meaning or construction of any provision of this
Agreement. 
 (b) Except as otherwise expressly provided in this Agreement or as the context otherwise requires, the following
rules of interpretation apply to this Agreement: (i) the singular includes the plural and the plural includes the singular; (ii) “or” and “any” are not exclusive and the words “include” and
“including,” and variations thereof, shall not be deemed to be terms of limitation, but rather shall be deemed to be followed by the words “without limitation”; (iii) a reference to any Contract includes supplements and
amendments; (iv) a reference to an Applicable Law includes any amendment or modification to such Applicable Law; (v) a reference to a Person includes its successors, heirs and permitted assigns; (vi) a reference to one gender shall
include any other gender; (vii) a reference in this Agreement to an Article, Section, Exhibit or Schedule is to the referenced Article, Section, Exhibit or Schedule of this Agreement; and (viii) “herein,” “hereunder,”
“hereof,” and words of similar import shall be deemed references to this Agreement as a whole and not to any particular Article, Section or other provision. 
 (c) The parties hereto agree that they have been represented by their own respective counsel during the negotiation, drafting, preparation and execution of this Agreement and, therefore, waive the
application of any Applicable Law or rule of construction providing that ambiguities in an agreement or other document will be construed against the party drafting such agreement or document. 

ARTICLE II 

DISPOSITION OF THE MEIP WARRANTS 
 Section 2.1. Cancellation of MEIP Warrants. In consideration of the limited waiver granted pursuant to Section 3.1, the Novogen Parties hereby agree that simultaneously
herewith the MEIP Warrants held by Seller Parent or any Affiliate thereof or otherwise beneficially owned by Seller Parent and representing the right to purchase one million (1,000,000) MEIP Shares (the “Cancellation
Warrants”), are cancelled. Subject to Section 2.2, (a) the Novogen Parties simultaneously herewith shall deliver to MEIP for further deliver to the warrant agent for the MEIP Warrants (the “Warrant
Agent”) a stock power with signature medallion guarantee in the form attached hereto as Exhibit A and (b) MEIP shall deliver to the Warrant Agent an irrevocable letter of instruction directing the Warrant Agent to immediately
cancel the Cancellation Warrants in the form attached hereto as Exhibit B. 
 Section 2.2. Distribution or Sale
of the Remaining MEIP Warrants. Prior to the closing of the Acquisition, the Novogen Parties shall (a) transfer, or cause to be transfered, to the Novogen Persons who are not Excluded Persons all Remaining MEIP Warrants
(including all right, title and interest in and to the Remaining MEIP Warrants) or (b) cause the sale of the Remaining MEIP Warrants to third parties who are not Excluded Persons, with such distribution or sale to be (i)
accomplished via transactions that are exempt from the registration requirements of the Securities Act and (ii) completed in a manner that complies with Applicable Law and the terms of the MEIP Warrants. 

  
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 ARTICLE III 
 LIMITED WAIVER OF THE NON-COMPETE PROVISIONS 
 Section 3.1. Limited
Waiver. MEIP hereby grants a limited waiver of the Non-Compete Provisions such that the restrictions set forth in Section 5.4(d) of the Asset Purchase Agreement shall not apply in respect of any Triaxial Intellectual Property (or any
Exploitation or licensing thereof) that does not infringe on or otherwise violate any of the Intellectual Property or Intellectual Property rights of MEIP, whether arising by Contract or under any Applicable Law. For purposes of this Agreement,
“Triaxial Intellectual Property” means Intellectual Property owned or licensed by Triaxial that is acquired, directly or indirectly, by Seller Parent in connection with the Acquisition provided that the same was developed
independently and without the use of any Proprietary Information. 
 ARTICLE IV 

ADDITIONAL AGREEMENTS 
 Section 4.1. Proprietary Information. 
 (a) The Novogen Parties
shall, following the execution hereof, (i) promptly upon discovery of any Proprietary Information in its possession or in the possession of its Affiliates (including Triaxial after the closing of the Acquisition) directors or employees notify
MEIP of the same and, at MEIP’s option, deliver to MEIP or destroy all such Proprietary Information and (ii) ensure that none of the Excluded Persons or Triaxial receives or gains access to such Proprietary Information. 

(b) The Novogen Parties shall not use, and shall take all reasonable action and precaution to ensure that none their respective
Affiliates (including Triaxial after the closing of the Acquisition), directors or employees use, any Proprietary Information. 

Section 4.2. Patent Filings/Cooperation. The Novogen Parties, Graham Kelly and Andrew Heaton hereby covenant and agree, as a
condition precedent to effectiveness of the limited waiver granted pursuant to Section 3.1, and as a condition to the continued effectiveness of the limited waiver granted pursuant to Section 3.1, that they shall cooperate fully with MEIP
in order to enable MEIP to perfect its ownership rights, title and interest in Seller Intellectual Property rights, including assisting MEIP to obtain patent protection and by executing any documentation necessary to perfect such ownership rights,
title and interest, including, but not limited to assignment and intellectual property application documents. The Novogen Parties, Graham Kelly and Andrew Heaton acknowledge that the Seller Intellectual Property Rights include International
Application No.: PCT/US2011/058815, and any and all Patents claiming priority from International Application No.: PCT/US2011/058815. In furtherance of the foregoing, Andrew Heaton shall execute and deliver simultaneously herewith the assignment
attached hereto as Exhibit C. 
 Section 4.3. Expenses. Except as expressly set forth herein, each
Novogen Party and MEIP shall bear its own costs and expenses incurred in connection with this Agreement and the transactions contemplated hereby. 

  
 4 

 Section 4.4. Other Deliveries. Each party shall deliver to the other (and
execute, if applicable) such other documentation relating to transactions contemplated by this Agreement as the other party or its counsel may reasonably request. 
 Section 4.5. Further Assurances. Before and after the closing, each party shall cooperate and take such action or cause to be taken such action as may be reasonably requested by another party
hereto in order to carry out the provisions and purposes of this Agreement and transactions contemplated hereby. 
 ARTICLE V

 REPRESENTATIONS AND WARRANTIES OF NOVOGEN PARTIES 

Each Novogen Party represents and warrants to MEIP that each statement contained in this Article V is true and correct as of
the date hereof: 
 Section 5.1. Organization. Such Novogen Party is a corporate entity duly organized, validly
existing under the laws of its jurisdiction of formation. 
 Section 5.2. Authority; Binding Agreements. Such
Novogen Party has all requisite power and authority to enter into this Agreement and any other agreements or instruments contemplated hereby, and to perform its obligations hereunder. This Agreement has been, or upon execution and delivery thereof
will be, duly executed and delivered by such Novogen Party. Upon execution and delivery by such Novogen Party, this Agreement will constitute a valid and binding obligation of such Novogen Party, enforceable in accordance with its terms. 

Section 5.3. Conflicts; Consents. The execution and delivery of this Agreement and any other agreements or instruments
contemplated hereby, the consummation of the transactions contemplated hereby, and compliance with any of the terms hereof by such Novogen Party do not and will not (i) conflict with or result in a breach of the constitutive or organizational
documents of such Novogen Party or (ii) violate any Applicable Law relating to such Novogen Party. 
 Section 5.4.
Title. Each Novogen Party and Affiliate thereof, if applicable, holding MEIP Warrants to be disposed of as set forth in Article II has as of the date hereof, and will have immediately prior to the disposition, good, valid, legal
and beneficial title to all such MEIP Warrants, free and clear of any liens, charges, claims, pledges, security interests and other rights or encumbrances whatsoever, whether arising by agreement, operation of law or otherwise, and there are no
restrictions on any such Person’s right to dispose of the MEIP Warrants held by such Person pursuant to Article II, other than those imposed by applicable securities laws. 

Section 5.5. Disclosure. No representation or warranty of such Novogen Party contained in this Agreement contains any untrue
statement of a material fact or omits to state a material fact necessary to make the statement contained herein not misleading. 

  
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 ARTICLE VI 
 REPRESENTATIONS AND WARRANTIES OF MEIP 
 MEIP represents and warrants to
each Novogen Party that each statement contained in this Article VI is true and correct as of the date hereof: 

Section 6.1. Organization. MEIP is a corporation, validly existing and in good standing under the laws of the State of
Delaware. 
 Section 6.2. Authority; Binding Agreements. MEIP has all requisite power and authority to enter into
this Agreement and any other agreements or instruments contemplated hereby, and to perform its obligations hereunder. This Agreement has been, or upon execution and delivery thereof will be, duly executed and delivered by MEIP. Upon execution and
delivery by MEIP, this Agreement will constitute a valid and binding obligation of MEIP, enforceable in accordance with its terms. 
 Section 6.3. Conflicts; Consents. The execution and delivery of this Agreement and any other agreements or instruments contemplated hereby, the consummation of the transactions contemplated
hereby, and compliance with any of the terms hereof by MEIP do not and will not (i) conflict with or result in a breach of the constitutive or organizational documents of MEIP or (ii) violate any Applicable Law relating to MEIP.

 ARTICLE VII 
 INDEMNIFICATION 
 Section 7.1. Survival; Expiration. The
representations and warranties contained in this Agreement shall survive the closing of the transactions contemplated hereby. The covenants, agreements and obligations of the parties shall survive until fully performed and discharged 

Section 7.2. Indemnification. Each party shall indemnify and hold harmless the other parties and its Affiliates, the
directors, officers, managers, employees and Representatives, from and against any and all Losses incurred or suffered, directly or indirectly, by any such Person arising from, by reason of or in connection with (a) any breach or inaccuracy of
any representation or warranty of such party set forth in this agreement and (b) any failure by such party to duly perform or fulfill any covenants or agreements required to be performed by party under this Agreement or under any other document
or instrument delivered by such party pursuant hereto. 
 ARTICLE VIII 

MISCELLANEOUS 
 Section 8.1. Governing Law; Jurisdiction; Venue; Service Of Process. 

(a) Governing Law. Construction and interpretation of this Agreement shall be governed by the laws of the State of New York,
excluding any conflicts or choice of law rule or principle that might otherwise refer construction or interpretation of this Agreement to the substantive Applicable Law of another jurisdiction. 

  
 6 

 (b) Jurisdiction; Venue; Service Of Process. The parties hereby irrevocably and
unconditionally consent to the exclusive jurisdiction of the courts of the State of New York and the United States District Court for the Southern District of New York for any Action (other than appeals therefrom) arising out of or
relating to this Agreement or otherwise in connection with the transactions contemplated hereby, and agree not to commence any Action, (other than appeals therefrom) related thereto except in such courts. The parties further hereby irrevocably and
unconditionally waive any objection to the laying of venue of any Action (other than appeals therefrom) arising out of or relating to this Agreement or otherwise in connection with the transactions contemplated hereby in the courts of the State of
New York or the United States District Court for the Southern District of New York, and hereby further irrevocably and unconditionally waive and agree not to plead or claim in any such court that any such Action brought in any such
court has been brought in an inconvenient forum. Each party hereto further agrees that service of any process, summons, notice or document by U.S. registered mail to its address set forth below shall be effective service of process for any Action
brought against it under this Agreement in any such court. 
 Section 8.2. Notices. All notices, requests, demands
and other communications that are required or may be given pursuant to the terms of this Agreement shall be in written form, and shall be deemed delivered (a) on the date of delivery when delivered by hand on a Business Day, (b) on the
Business Day designated for delivery if sent by reputable overnight courier maintaining records of receipt and (c) on the date of transmission when sent by facsimile, electronic mail or other electronic transmission during normal business hours
on a Business Day, with confirmation of transmission by the transmitting equipment; provided, however, that any such communication delivered by facsimile or other electronic transmission shall only be effective if within two Business
Days of such transmission such communication is also delivered by hand or deposited with a reputable overnight courier maintaining records of receipt for delivery on the Business Day immediately succeeding such day of deposit. All such
communications shall be addressed to the parties at the address set forth as follows, or at such other address as a party may designate upon 10 days’ prior written notice to the other party. 

If to MEIP, to: 
 MEI Pharma, Inc. 
 11975 El Camino Real, Suite 101 

San Diego, CA 92130 
 Facsimile: 858-792-5406 
 Attention: Daniel Gold, Chief Executive Officer

 with a copy (which shall not constitute notice) to: 

Morgan, Lewis & Bockius LLP 
 101 Park Avenue 
 New York, NY 10178 

Facsimile: (212) 309-6001 
 Attention: Steven A. Navarro 

  
 7 

 If to any of the Novogen Parties, to: 

Novogen Limited 
 1-7 Waterloo Road, Level 1 
 North Ryde, NSW 2113 Australia 

Facsimile: 612 9878 0055 
 Attention: The Chairman 
 If to Graham Kelly, to: 

66 Boundary Rd 

Wahroonga 
 NSW
2076 Australia 
 Facsimile:
                     
 If
to Andrew Heaton, to: 
 3/24 Benjamin St 
 Trevallyn 
 Tasmania 7250 Australia 

Facsimile:                     

 Section 8.3. Benefits of Agreement. All of the terms and provisions of this Agreement shall be binding upon and
inure to the benefit of the parties hereto and their respective successors and permitted assigns. Except as expressly set forth herein, this Agreement is for the sole benefit of the parties hereto and not for the benefit of any third party.

 Section 8.4. Amendments and Waivers. No modification, amendment or waiver of any provision of this Agreement,
nor any consent to or approval of any departure herefrom, shall be effective unless it is in writing and signed by the party against whom enforcement of any such modification, amendment, waiver, consent or approval is sought. Such modification,
amendment, waiver, consent or approval shall be effective only in the specific instance and for the purpose for which given. Neither the failure of any party to enforce, nor the delay of any party in enforcing, any condition or part of this
Agreement at any time shall be construed as a waiver of that condition or part or forfeit any rights to future enforcement thereof. 
 Section 8.5. WAIVER OF JURY TRIAL. EACH PARTY IRREVOCABLY AND UNCONDITIONALLY WAIVES ANY RIGHT TO TRIAL BY JURY WITH RESPECT TO ANY ACTION RELATING TO OR ARISING OUT OF THIS AGREEMENT OR THE
TRANSACTIONS CONTEMPLATED HEREBY. 
 Section 8.6. Assignment. This Agreement and the Asset Purchase Agreement and
the rights and obligations hereunder and thereunder shall not be assignable (i) by any of the Novogen Parties without the prior written consent of MEIP or (ii) by MEIP without the prior written consent of Seller Parent. Any attempted
assignment in violation of this Section 8.6 shall be null and void. 

  
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 Section 8.7. Entire Agreement. This Agreement and the Asset Purchase Agreement,
together with the Exhibits attached hereto and thereto and all other agreements executed in connection herewith and therewith, constitute the entire agreement among the parties with respect to the subject matter hereof and supersede all prior
agreements or understandings among the parties with respect to the subject matter hereof. Except as modified by the term of this Agreement, the Asset Purchase Agreement shall remain in full force and effect without further modification. 

Section 8.8. Counterparts. This Agreement may be executed in any number of counterparts, and each such counterpart hereof
shall be deemed to be an original instrument, but all such counterparts together shall constitute but one agreement. Delivery of an executed counterpart of a signature page of this Agreement by facsimile or other electronic transmission shall be
effective as delivery of a manually executed original counterpart of this Agreement. 
 [Remainder of page intentionally left
blank] 

  
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 IN WITNESS WHEREOF, the parties have executed this Agreement as of the date first written
above. 
  

			
	MEI PHARMA, Inc.
		
	By:	 	 /s/ Daniel P. Gold

	Name:	 	Daniel P. Gold
	Title:	 	President & Chief Executive Officer
	
	NOVOGEN LIMITED
		
	By:	 	 /s/ William D. Rueckert

	Name:	 	William D. Rueckert
	Title:	 	Director
		
	By:	 	 /s/ Josiah T. Austin

	Name:	 	Josiah T. Austin
	Title:	 	Director
	
	NOVOGEN RESEARCH PTY LIMITED
		
	By:	 	 /s/ William D. Rueckert

	Name:	 	William D. Rueckert
	Title:	 	Director
		
	By:	 	 /s/ Josiah T. Austin

	Name:	 	Josiah T. Austin
	Title:	 	Director
	
	FOR PURPOSES OF SECTION 4.2 AND ARTICLES VII AND VIII ONLY
	
	 /s/ Graham Kelly

	Graham Kelly
	
	 /s/ Andrew Heaton

	Andrew Heaton

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