Document:

Letter Agreement by and among Myrexis, Inc., MSMB Healthcare LP

 Exhibit 10.2 
 MYREXIS, INC. 
 305 Chipeta Way 

Salt Lake City, UT 84108 
 August 8, 2012 
 MSMB Healthcare LP 
 MSMB Healthcare Investors LLC 
 MSMB Healthcare Management LLC 

MSMB Capital Management LLC 

330 Madison Avenue, 6th Floor 
 New
York, NY 10017 
 Attn: Martin Shkreli 

Dear Martin: 
 I am writing
this letter on behalf of Myrexis, Inc. (“Myrexis” or “we”), addressed to your attention for each and all of the above-named MSMB entities (collectively, the “MSMB Parties”) to memorialize the agreed-upon basis for one
or more of the MSMB Parties and/or you possibly to acquire additional shares or other securities in Myrexis. I am simultaneously sending a separate letter addressed to you individually to complete the memorializing of such agreement. 

As you know, we adopted a Tax Benefits Preservation Rights Plan on March 29, 2012 (the “Plan”), which we publicly
announced the next day, to enable our Board of Directors (the “Board”) to protect the use of our net operating losses and certain other tax attributes under Section 382 of the Internal Revenue Code of 1986, as amended, and the
Treasury Regulations thereunder (together, “Section 382”). We and you agree that it is valuable to Myrexis and also to the MSMB Parties and you for the Board to be able to manage the usability of such tax attributes, while guarding against
the MSMB Parties’ or your triggering highly dilutive, and therefore adverse, provisions of the Plan. We and the MSMB Parties and you also hereby agree that it is important to be clear about the voting commitment the MSMB Parties and you are
making to induce us to enter into this letter agreement. 
 Our agreement with the MSMB Parties, and with you individually in
the above-mentioned separate letter agreement, is as follows: 
  

	 	•	 	 The Myrexis shares and any other Myrexis securities constituting “stock” (as defined under Section 382) owned by all of the MSMB Parties
and you in the aggregate, including any securities or rights or interests in securities the ownership or holding of which by any other person or entity would be aggregated with any securities of Myrexis owned by you, must at all times from now
through the completion of the 2013 annual meeting of shareholders represent less than 4.99% ownership in Myrexis; and 

  Page
 2
 
 August 8, 2012 

 

	 	•	 	 On any matter presented to Myrexis’ shareholders for their vote (or written consent in any case of action by shareholders by written consent in
lieu of a meeting), by whomever presented, including any director election or any other proposal presented for a shareholder vote (or written consent), from now through the completion of the 2013 annual meeting of shareholders, the MSMB Parties, you
and their and your affiliates will vote (or deliver their and your written consents with respect to) all Myrexis’ shares owned by them as recommended by the Board (and, not less than five (5) business days prior to any meeting at which
such shares will be voted, provide to such officer of Myrexis as Myrexis designates irrevocable proxies so to vote such shares, in a form to be provided to you by Myrexis, which proxies will be coupled with an interest) as recommended by the Board,
provided that either: 

  

	 	•	 	 Jason Aryeh is included in the majority of the Board approving the recommendation; or 

 

	 	•	 	 Jason Aryeh abstains or otherwise does not vote as a member of the Board on the recommendation, but he votes or causes to be voted (or provides a
written consent or causes a written consent to be provided with respect to) Myrexis’ shares he owns or controls as recommended by the Board. 

 For purposes of this letter agreement, “own” and variations thereof with respect to shares or other securities of Myrexis shall have the same meanings as under Section 382 during the time
when the Plan is in effect and otherwise shall mean “beneficial own” and variations thereof under the Exchange Act. 

Without limiting any of the Company’s rights or remedies hereunder and under the previous agreement dated October 18, 2011 by
and between Myrexis and the MSMB Parties Agreement (the “Agreement”), in the event that any of the MSMB Parties and you owning shares in Myrexis refuses or otherwise fails to deliver or cause to be delivered, timely and completely, all of
the above-mentioned proxies, this letter agreement itself shall, at the election of Myrexis, be deemed to constitute such a proxy, with all the attributes provided for hereinabove, and Myrexis’ President shall be the designated lawful
proxyholder and attorney-in-fact, with full power of substitution, in any such case. 
 To the extent this letter agreement
contains provisions which are in addition to or inconsistent with the provisions of the Agreement, such additional provisions shall be deemed to be provisions incorporated into the Agreement and any such inconsistent provisions hereof shall also be
deemed to be incorporated therein, superseding the inconsistent provisions thereof. In these respects this letter agreement shall be deemed to amend the Agreement, which as so amended shall continue in force and effect. 

  Page
 3
 
 August 8, 2012 

 

 Please confirm the agreement of the MSMB Parties with us as to the foregoing by
countersigning and returning to Myrexis an identical counterpart of this letter agreement on their behalf. 
  

			
	Very truly yours,
	
	MYREXIS, INC.
		
	By:	 	 /s/ Richard B. Brewer

		 	Name: Richard B. Brewer
		 	Title: President

  

			
	ACCEPTED AND AGREED TO:
	
	MSMB HEALTHCARE LP
	
	By: MSMB HEALTHCARE INVESTORS LLC, its General Partner
		
	By:	 	 /s/ Martin Shkreli

		 	Name: Martin Shkreli
		 	Title: Managing Member
	
	MSMB HEALTHCARE INVESTORS LLC
		
	By:	 	 /s/ Martin Shkreli

		 	Name: Martin Shkreli
		 	Title: Managing Member
	
	MSMB HEALTHCARE MANAGEMENT LLC
		
	By:	 	 /s/ Martin Shkreli

		 	Name: Martin Shkreli
		 	Title: Managing Member
	
	MSMB CAPITAL MANAGEMENT LLC
		
	By:	 	 /s/ Martin Shkreli

		 	Name: Martin Shkreli
		 	Title: Managing MemberLetter Agreement by and between Myrexis, Inc. and Martin Shkreli

 Exhibit 10.3 
 MYREXIS, INC. 
 305 Chipeta Way 

Salt Lake City, UT 84108 
 August 8, 2012 
 Martin Shkreli 
 c/o MSMB Capital Management LLC 
 330 Madison Avenue, 6th Floor 
 New York, New York 10017 
 Dear Martin: 

This letter agreement is being executed and delivered in connection with a letter agreement of the same date by and among Myrexis, Inc.
(“Myrexis” or “we”) and certain parties referred to therein collectively as the MSMB Parties (the “2012 Letter Agreement”), providing for the agreed-upon basis for any one or more of the MSMB Parties and you possibly to
acquire shares in or other securities of Myrexis. The 2012 Letter Agreement amends a previous agreement dated as of October 18, 2011 by and among Myrexis and the MSMB Parties (the “2011 Agreement”), in connection with which we and you
executed and delivered a letter agreement (the “2011 Letter Agreement”). 
 For the benefit to you from the 2012
Letter Agreement, and other good and valuable consideration, the receipt and sufficiency of which are hereby mutually acknowledged, and in order to induce Myrexis to enter into the 2012 Letter Agreement, you by your countersignature below agree not
to, and not to cause or permit any other existing or future Affiliate (as defined in the 2011 Agreement) of yours to, take any action or refrain from taking any action which, if done or refrained from being done by any MSMB Party, would constitute a
breach of the 2011 Agreement as amended by the 2012 Letter Agreement. 
 You by your countersignature below acknowledge and
agree that your obligations under this letter agreement and the 2011 Letter Agreement are primary obligations and that, in the event of any breach by you of any of your obligations hereunder or under the 2011 Letter Agreement, Myrexis shall be
entitled to legal and equitable relief against you. No modification of the 2012 Letter Agreement, the 2011 Agreement or the 2011 Letter Agreement shall release you from or affect any of your obligations hereunder or under the 2011 Letter Agreement,
unless expressly provided for in such modification. 
 Please confirm your agreement with the foregoing by signing and returning
to the undersigned the duplicate copy of this letter enclosed herewith, whereupon this letter agreement shall take effect as an agreement between Myrexis and you. 
  

			
	MYREXIS, INC.
		
	By:	 	 /s/ Richard B. Brewer

		 	Name: Richard B. Brewer
		 	Title: President

 Page 2 
 Myrexis, Inc. 
 August 8, 2012 
  

	
	ACCEPTED AND AGREED TO:
	
	 /s/ Martin Shkreli

	Martin ShkreliSecond Supplemental Indenture

 Exhibit 4.1 

 
  
 STANCORP FINANCIAL GROUP, INC. 
 and 

U.S. BANK NATIONAL ASSOCIATION, 
 as Trustee 
  

 
 SECOND
SUPPLEMENTAL INDENTURE 
 Dated as of August 10, 2012 

to 

INDENTURE 

Dated as of September 25, 2002 
  

 
 5.00% Senior
Notes due 2022 
  
  

 SECOND SUPPLEMENTAL INDENTURE, dated as of the 10th day of August, 2012 (this
“Second Supplemental Indenture”), between StanCorp Financial Group, Inc., a corporation duly organized and existing under the laws of the State of Oregon (hereinafter sometimes referred to as the “Company”),
and U.S. Bank National Association, a national banking association as trustee (hereinafter sometimes referred to as the “Trustee”) under the Indenture dated as of September 25, 2002 between the Company and the Trustee,
as previously supplemented (the “Indenture”). 
 WHEREAS, the Company executed and delivered the
Indenture to the Trustee to provide for the future issuance of its debt securities (the “Securities”), which Securities are to be issued from time to time in such series as may be determined by the Company under the Indenture, in an
unlimited aggregate principal amount which may be authenticated and delivered thereunder as in the Indenture provided; and 

WHEREAS, the Indenture is incorporated herein by this reference; and 

WHEREAS, pursuant to the terms of the Indenture, the Company desires to provide for the establishment of a new series of its
Securities to be known as its 5.00% Senior Notes due 2022 (such series being hereinafter referred to as the “5.00% Senior Notes”), the form and substance of such 5.00% Senior Notes and the terms, provisions and conditions thereof to
be set forth as provided in the Indenture and this Second Supplemental Indenture; and 
 WHEREAS, the Company desires and
has requested the Trustee to join with it in the execution and delivery of this Second Supplemental Indenture, and all requirements necessary to make this Second Supplemental Indenture a valid instrument, in accordance with its terms, and to make
the 5.00% Senior Notes, when executed by the Company and authenticated and delivered by the Trustee, the valid obligations of the Company, have been performed and fulfilled, and the execution and delivery hereof have been in all respects duly
authorized; 
 NOW, THEREFORE, in consideration of the purchase and acceptance of the 5.00% Senior Notes by the
holders thereof, and for the purpose of setting forth, as provided in the Indenture, the form and substance of the 5.00% Senior Notes and the terms, provisions and conditions thereof, the Company covenants and agrees with the Trustee as
follows: 
 Article One 
 Additional Definitions 
 Section 1.01. For all purposes of this
Second Supplemental Indenture, capitalized terms used herein without definition shall have the meanings specified in the Indenture. 
 Section 1.02. The terms defined in this Section, for all purposes of this Second Supplemental Indenture, shall have the respective meanings specified in this Section. 

“Adjusted Treasury Rate” means, with respect to any date of redemption, the rate per year equal to the semiannual
equivalent yield to maturity of the Comparable Treasury Issue, assuming a price for the Comparable Treasury Issue (expressed as a percentage of its principal amount) equal to the Comparable Treasury Price for that date of redemption. 

 “Comparable Treasury Issue” means the United States Treasury security
selected by the Quotation Agent as having a maturity comparable to the remaining term of the Securities to be redeemed that would be used, at the time of selection and under customary financial practice, in pricing new issues of corporate debt
securities of comparable maturity to the remaining term of the 5.00% Senior Notes. 
 “Comparable Treasury
Price” means, with respect to any date of redemption, the average of the Reference Treasury Dealer Quotations for the date of redemption, after excluding the highest and lowest Reference Treasury Dealer Quotations, or if the Trustee obtains
fewer than three Reference Treasury Dealer Quotations, the average of all Reference Treasury Dealer Quotations. 

“Quotation Agent” means Barclays Capital Inc., Goldman, Sachs & Co. and J.P. Morgan Securities LLC, or another
Reference Treasury Dealer appointed by the Company. 
 “Reference Treasury Dealer” means Barclays Capital Inc.,
Goldman, Sachs & Co. and J.P. Morgan Securities LLC, and their respective successors and, at the Company’s option, other nationally recognized investment banking firms that are primary dealers of U.S. government securities in New York
City. If any of the foregoing ceases to be a primary dealer of U.S. government securities in New York City, the Company must substitute another primary dealer of U.S. government securities. 

“Reference Treasury Dealer Quotations” means, with respect to each Reference Treasury Dealer and any date of redemption,
the average, as determined by the Trustee, of the bid and asked prices for the Comparable Treasury Issue (expressed in each case as a percentage of its principal amount) quoted in writing to the Trustee by the Reference Treasury Dealer at 5:00 p.m.,
New York City time, on the third business day before the date of redemption. 
 “Stated Maturity” means
August 15, 2022. 
 Article Two 
 General Terms and Conditions of 
 the 5.00% Senior Notes

 Section 2.01. There is hereby established, and authenticated and delivered by the Trustee on the date hereof,
a series of Securities designated the “5.00% Senior Notes” limited in initial aggregate principal amount to $250,000,000; provided, however, that the aggregate principal amount of the 5.00% Senior Notes may be increased in the future,
without the consent of the holders of the 5.00% Senior Notes, on the same terms and with the same CUSIP and ISIN numbers as the 5.00% Senior Notes; provided further, however, that if the additional notes are not fungible with the 5.00% Senior Notes
for U.S. federal income tax purposes, the additional notes will have a separate CUSIP number. The 5.00% Senior Notes shall mature and the principal shall be due and payable, together with all accrued and unpaid interest thereon, on the Stated
Maturity, subject to the provisions of the Indenture relating to the acceleration of maturity. The 5.00% Senior Notes shall be issued in fully registered form without coupons in denominations of $2,000 and integral multiples of $1,000 in excess
thereof. The 5.00% Senior Notes shall be issued in the form set forth in Exhibit A hereto. 

  
 2 

 Section 2.02. The 5.00% Senior Notes shall be issued in the form of one or
more Global Securities and registered in the name of the Depository (which shall be The Depository Trust Company) or its nominee. 5.00% Senior Notes represented by a Global Security will not be exchangeable for, and will not otherwise be
issuable as, 5.00% Senior Notes in certificated form, except as provided in Section 2.11 of the Indenture and except if there shall have occurred and be continuing an Event of Default and the holders of a majority in aggregate principal
amount of 5.00% Senior Notes determine to discontinue the system of book-entry transfers through the Depository. Any Global Security that is exchangeable pursuant to the preceding sentence shall be exchangeable for 5.00% Senior Notes
registered in such names as the Depository shall direct. 
 Section 2.03. The Global Securities described above may
not be transferred except by the Depository to a nominee of the Depository or by a nominee of the Depository to the Depository or another nominee of the Depository or to a successor Depository or its nominee. 

Owners of beneficial interests in such Global Securities will not be considered the holders thereof for any purpose under the Indenture,
and no Global Security representing a 5.00% Senior Note shall be exchangeable, except for another Global Security of like denomination and tenor to be registered in the name of the Depository or its nominee or to a successor Depository or its
nominee. The rights of holders of such Global Securities shall be exercised only through the Depository. 

Section 2.04. Each 5.00% Senior Note will bear interest at the rate of 5.00% per annum from and including the date
of original issuance or from the most recent Interest Payment Date (as defined below) to which interest has been paid or duly provided for until the principal thereof becomes due and payable, and on any overdue principal and (to the extent that
payment of such interest is enforceable under applicable law) on any overdue installment of interest at the same rate per annum. Interest shall be paid semiannually in arrears on February 15 and August 15 of each year (each, an
“Interest Payment Date”), commencing on February 15, 2013 to the person in whose name such 5.00% Senior Note or any predecessor 5.00% Senior Note is registered at the close of business on the last day of the month
preceding the month in which such Interest Payment Date occurs (the “Record Date”), provided that the interest payable at the Stated Maturity will be paid to the person to whom principal is payable. Any such interest installment not
punctually paid or duly provided for on any Interest Payment Date shall forthwith cease to be payable to the registered holder on the relevant Record Date, and may be paid to the person in whose name the 5.00% Senior Note (or one or more
predecessor Securities) is registered at the close of business on a special record date to be fixed by the Trustee for the payment of such defaulted interest, notice whereof shall be given to the registered holders of the 5.00% Senior Notes not
less than 10 days prior to such special record date, or may be paid at any time in any other lawful manner not inconsistent with the requirements of any securities exchange on which the 5.00% Senior Notes may be listed, and upon such notice as
may be required by such exchange, all as more fully provided in the Indenture. 

  
 3 

 The amount of interest payable for any period will be computed on the basis of a 360-day
year of twelve 30-day months and, for any period shorter than a full calendar month, on the basis of the actual number of days elapsed in such period. In the event that any date on which interest is payable on the 5.00% Senior Notes is not a
Business Day, then payment of interest payable on such date will be made on the next succeeding day that is a Business Day (and without any interest or other payment in respect of any such delay), except that, if such Business Day is in the next
succeeding calendar year, such payment shall be made on the immediately preceding Business Day (and without any reduction in interest or other payment in respect of any such early payment), in each case with the same force and effect as if made on
the date such payment was originally payable. 
 Payment of the principal and interest due at the Stated Maturity of the
5.00% Senior Notes shall be made upon surrender of the 5.00% Senior Notes at the Corporate Trust Office. The principal of and interest on the 5.00% Senior Notes shall be paid in such coin or currency of the United States of America as
at the time of payment is legal tender for payment of public and private debts. Payments of interest (including interest on any Interest Payment Date) will be made, subject to such surrender where applicable, at the option of the Company,
(i) by check mailed to the address of the person entitled thereto as such address shall appear in the Security Register or (ii) by wire transfer in immediately available funds at such place and to such account at a banking institution in
the United States as may be designated in writing to the Trustee at least 14 days prior to the date for payment by the person entitled thereto. 
 Section 2.05. The 5.00% Senior Notes will be senior unsecured obligations of the Company and will rank equally in right of payment with all of the other senior unsecured, unguaranteed and
unsubordinated indebtedness of the Company from time to time outstanding. The 5.00% Senior Notes will rank senior to any subordinated indebtedness of the Company. 
 Article Three 
 Redemption of the 5.00% Senior Notes 

Section 3.01. Subject to the terms of Article Three of the Indenture, the Company shall have the right to redeem the
5.00% Senior Notes, in whole, at any time, or in part, from time to time, at a redemption price (the “Redemption Price”) equal to the greater of (i) 100% of the principal amount of the 5.00% Senior Notes to be
redeemed and (ii) the sum of the present values of the remaining scheduled payments of principal and interest on the 5.00% Senior Notes to be redeemed (not including any portion of such payments of interest accrued to the date of
redemption) discounted to the date of redemption on a semiannual basis (assuming a 360-day year consisting of twelve 30-day months) at the Adjusted Treasury Rate, plus 50 basis points; plus, in each case, any accrued and unpaid interest thereon to
the date of such redemption. If the 5.00% Senior Notes are only partially redeemed pursuant to this Section 3.01, the 5.00% Senior Notes will be redeemed pro rata by the Trustee. The Company may not redeem the 5.00% Senior Notes
in part unless all accrued and unpaid interest has been paid in full on all outstanding 5.00% Senior Notes for all interest periods terminating on or prior to the date of redemption. 

Notwithstanding Section 3.02 of the Indenture, the notice of redemption with respect to the foregoing redemption need not set forth
the Redemption Price but only the manner of calculation thereof. 

  
 4 

 The Company shall notify the Trustee of the Redemption Price with respect to the foregoing
redemption promptly after the calculation thereof. The Trustee shall not be responsible for calculating said Redemption Price. 

Article Four 
 Form of 5.00% Senior Notes 
 The 5.00% Senior Notes and the
Trustee’s Certificate of Authentication to be endorsed thereon are to be substantially in the forms set forth in Exhibit A attached hereto. 
 Article Five 
 Original Issue of 5.00% Senior Notes 

5.00% Senior Notes in the aggregate principal amount of $250,000,000 may, upon execution of this Second Supplemental Indenture, or
from time to time thereafter, be executed by the Company and delivered to the Trustee for authentication, and the Trustee shall thereupon authenticate and deliver such Notes to or upon the written order of the Company, signed by its Chairman, Chief
Executive Officer or President and its Treasurer or an Assistant Treasurer, Controller or Assistant Controller, without any further action by the Company. 
 Article Six 
 Miscellaneous Provisions 

Section 6.01. The Indenture, as supplemented by this Second Supplemental Indenture, is in all respects ratified and
confirmed, and this Second Supplemental Indenture shall be deemed part of the Indenture in the manner and to the extent herein and therein provided and shall be read, taken and construed as one and the same instrument. 

Section 6.02. The recitals herein contained are made by the Company and not by the Trustee, and the Trustee assumes no
responsibility for the correctness thereof. The Trustee makes no representation as to the validity or sufficiency of this Second Supplemental Indenture. 
 Section 6.03. This Second Supplemental Indenture shall be governed by and construed in accordance with the laws of the State of New York applicable to agreements made and performed in said
state. 
 Section 6.04. This Second Supplemental Indenture may be executed in any number of counterparts, each of
which shall be an original; but such counterparts shall together constitute but one and the same instrument. 

  
 5 

 IN WITNESS WHEREOF, the parties hereto have caused this Second Supplemental Indenture
to be duly executed on the date or dates indicated in the acknowledgments and as of the day and year first above written. 
  

					
	STANCORP FINANCIAL GROUP, INC.
		
	By:	 	 /s/ J. Greg Ness

		 	Name:	 	J. Greg Ness
		 	Title:	 	Chairman, President and
		 		 	Chief Executive Officer

  

					
	Attest:	 	 /s/ Floyd F. Chadee

		 	Name:	 	Floyd F. Chadee
		 	Title:	 	Senior Vice President and
		 		 	Chief Financial Officer

  

					
	U.S. BANK NATIONAL ASSOCIATION
	as Trustee
		
	By:	 	 /s/ Cheryl Nelson

		 	Name:	 	Cheryl Nelson
		 	Title:	 	Vice President

  
 Signature
Page to Second Supplemental Indenture 

 Exhibit A 
 (FORM OF FACE OF NOTE) 
 THIS NOTE IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE
HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF A DEPOSITORY OR A NOMINEE OF A DEPOSITORY. THIS NOTE IS EXCHANGEABLE FOR NOTES REGISTERED IN THE NAME OF A PERSON OTHER THAN THE DEPOSITORY OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES
DESCRIBED IN SECTION 2.11 OF THE INDENTURE, AND NO TRANSFER OF THIS NOTE (OTHER THAN A TRANSFER OF THIS NOTE AS A WHOLE BY THE DEPOSITORY TO A NOMINEE OF THE DEPOSITORY OR BY A NOMINEE OF THE DEPOSITORY TO THE DEPOSITORY OR ANOTHER NOMINEE OF THE
DEPOSITORY) MAY BE REGISTERED EXCEPT IN THE LIMITED CIRCUMSTANCES DESCRIBED IN SECTION 2.11 OF THE INDENTURE. 
 UNLESS THIS NOTE IS PRESENTED
BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY TO THE ISSUER OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY NOTE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR SUCH OTHER NAME AS REQUESTED BY AN
AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY AND ANY PAYMENT HEREON IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY, ANY TRANSFER, PLEDGE OR OTHER
USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 
  

					
	 No.[            ]
	  	$	250,000,000	  

 CUSIP No. 852891 AC4 
 ISIN No. US852891AC44 

  
 A - 1

 STANCORP FINANCIAL GROUP, INC. 

5.00% Senior Note due 2022 
 STANCORP FINANCIAL GROUP, INC., a corporation duly organized and existing under the laws of the State of Oregon (herein referred to as the “Company”, which term includes any successor
corporation under the Indenture), for value received, hereby promises to pay to Cede & Co., or registered assigns, the principal sum of Two Hundred Fifty Million U.S. Dollars ($250,000,000), on August 15, 2022 (the “Stated
Maturity”), and to pay interest on such principal sum from and including August 10, 2012 or from the most recent Interest Payment Date (as defined below) to which interest has been paid or duly provided for, payable semiannually in arrears
on February 15 and August 15 of each year (each such date, an “Interest Payment Date”), commencing on February 15, 2013, at the rate of 5.00% per annum, until the principal hereof shall have become due and payable, and
on any overdue principal and premium, if any, and (to the extent that payment of such interest is enforceable under applicable law) on any overdue installment of interest at the same rate per annum. The amount of interest payable on any Interest
Payment Date shall be computed on the basis of a 360-day year of twelve 30-day months and, for any period shorter than a full calendar month, on the basis of the actual number of days elapsed in such period. In the event that any date on which
interest is payable on this Note is not a Business Day, then payment of interest payable on such date will be made on the next succeeding day which is a Business Day (and without any interest or other payment in respect of any such delay), except
that, if such Business Day is in the next succeeding calendar year, such payment shall be made on the immediately preceding Business Day (and without any reduction in interest or other payment in respect of any such early payment), in each case with
the same force and effect as if made on such date. The interest installment so payable, and punctually paid or duly provided for on any Interest Payment Date will, as provided in the Indenture, be paid to the person in whose name this Note (or one
or more Predecessor Securities, as defined in the Indenture) is registered at the close of business on the last day of the month preceding the month in which such Interest Payment Date occurs (each, a “Record Date”). Any such interest
installment not punctually paid or duly provided for on any Interest Payment Date shall forthwith cease to be payable to the registered holder on the relevant Record Date, and may be paid to the person in whose name this Note (or one or more
Predecessor Securities) is registered at the close of business on a special record date to be fixed by the Trustee for the payment of such defaulted interest, notice whereof shall be given to the registered holders of this series of Notes not less
than 10 days prior to such special record date, or may be paid at any time in any other lawful manner not inconsistent with the requirements of any securities exchange on which the Notes may then be listed, and upon such notice as may be required by
such exchange, all as more fully provided in the Indenture hereinafter referred to. 
 Payment of the principal of and interest
due at the Stated Maturity of this Note shall be made upon surrender of this Note at the Corporate Trust Office. The principal of and interest on this Note shall be paid in such coin of currency of the United States of America as at the time of
payment is legal tender for payment of public and private debts. Payment of interest (including interest on an Interest Payment Date) will be made, subject to such surrender where applicable, at the option of the Company, (i) by check mailed to
the address of the person entitled thereto as such address shall appear in the Security Register or (ii) by wire transfer in immediately available funds at such place and to such account at a banking institution in the United States as may be
designated in writing to the Trustee at least 15 days prior to the date for payment by this person entitled thereto. 
 The
Senior Notes (as defined on the reverse hereof) will be senior unsecured obligations of the Company and will rank equally in right of payment with all of the other senior unsecured, unguaranteed and unsubordinated indebtedness of the Company from
time to time outstanding. The Senior Notes will rank senior to any subordinated indebtedness of the Company. 
 REFERENCE IS
HEREBY MADE TO THE FURTHER PROVISIONS OF THIS NOTE SET FORTH ON THE REVERSE HEREOF, WHICH FURTHER PROVISIONS SHALL FOR ALL PURPOSES HAVE THE SAME EFFECT AS IF SET FORTH AT THIS PLACE. 

  
 A - 2

 This Note shall not be entitled to any benefit under the Indenture hereinafter referred to,
be valid or become obligatory for any purpose until the Certificate of Authentication hereon shall have been signed by or on behalf of the Trustee. 
 IN WITNESS WHEREOF, the Company has caused this Note to be executed. 
  

			
	STANCORP FINANCIAL GROUP, INC.
		
	By	 	  

		 	Name:
		 	Title:

  

	
	 Attest:

	
	  
 Name:

	 Title:

  
 A - 3

 Certificate of Authentication 

This is one of the Notes of the series of Securities described in the within-mentioned Indenture. 

Dated: [—], 2012 

 

			
	U.S. BANK NATIONAL ASSOCIATION
	as Trustee
		
	By	 	  

		 	            Authorized Signatory

  
 A - 4

 (Reverse) 
 5.00% Senior Note due 2022 
 (continued) 

This Note is one of a duly authorized series of senior notes of the Company (herein sometimes referred to as the “Securities”),
specified in the Indenture (as defined below), all issued or to be issued in one or more series under and pursuant to an Indenture dated as of September 25, 2002 (the “Indenture”) duly executed and delivered between the Company and
U.S. Bank National Association, a national banking association, as Trustee (herein referred to as the “Trustee”), to which Indenture and all indentures supplemental thereto (including, without limitation, the Second Supplemental Indenture,
dated as of August 10, 2012, between the Company and the Trustee) reference is hereby made for a description of the rights, limitations of rights, obligations, duties and immunities thereunder of the Trustee, the Company and the holders of the
Securities and the terms upon which said Securities are, and are to be, authenticated and delivered. By the terms of the Indenture, the Securities are issuable in series which may vary as to amount, date of maturity, rate of interest and in other
respects as in the Indenture provided. This Note is one of a series designated as the 5.00% Senior Notes due 2022, limited in initial aggregate principal amount of $250,000,000; provided, however, that the aggregate principal amount of the
Securities may be increased in the future, without the consent of the holders of the Securities, on the same terms and with the same CUSIP and ISIN numbers as the Securities; provided further, however, that if the additional notes are not fungible
with the 5.00% Senior Notes for U.S. federal income tax purposes, the additional notes will have a separate CUSIP number. 

Subject to the terms of Article Three of the Indenture, the Company shall have the right to redeem the Securities of this series at the
option of the Company, in whole or in part at any time and from time to time (an “Optional Redemption”), at a redemption price equal to the greater of (i) 100% of the principal amount of the Securities of this series to be redeemed
and (ii) the sum of the present values of the remaining scheduled payments of principal and interest on the Notes to be redeemed (not including any portion of such payments of interest accrued to the date of redemption) discounted to the date
of redemption on a semiannual basis (assuming a 360-day year consisting of twelve 30-day months) at the Adjusted Treasury Rate, plus 50 basis points; plus, in each case, any accrued and unpaid interest thereon to the date of such redemption. If the
Securities of this series are only partially redeemed by the Company pursuant to an Optional Redemption, the Securities of this series will be redeemed pro rata by the Trustee. 

“Adjusted Treasury Rate” means, with respect to any date of redemption, the rate per year equal to the semiannual equivalent
yield to maturity of the Comparable Treasury Issue, assuming a price for the Comparable Treasury Issue (expressed as a percentage of its principal amount) equal to the Comparable Treasury Price for that date of redemption. 

“Comparable Treasury Issue” means the United States Treasury security selected by the Quotation Agent as having a maturity
comparable to the remaining term of the Securities to be redeemed that would be used, at the time of selection and under customary financial practice, in pricing new issues of corporate debt securities of comparable maturity to the remaining term of
the 5.00% Senior Notes. 

  
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 “Comparable Treasury Price” means, with respect to any date of redemption, the
average of the Reference Treasury Dealer Quotations for the date of redemption, after excluding the highest and lowest Reference Treasury Dealer Quotations, or if the Trustee obtains fewer than three Reference Treasury Dealer Quotations, the average
of all Reference Treasury Dealer Quotations. 
 “Quotation Agent” means Barclays Capital Inc., Goldman,
Sachs & Co. and J.P. Morgan Securities LLC, or another Reference Treasury Dealer appointed by the Company. 

“Reference Treasury Dealer” means Barclays Capital Inc., Goldman, Sachs & Co. and J.P. Morgan Securities LLC, and
their respective successors and, at the Company’s option, other nationally recognized investment banking firms that are primary dealers of U.S. government securities in New York City. If any of the foregoing ceases to be a primary dealer of
U.S. government securities in New York City, the Company must substitute another primary dealer of U.S. government securities. 

“Reference Treasury Dealer Quotations” means, with respect to each Reference Treasury Dealer and any date of redemption, the
average, as determined by the Trustee, of the bid and asked prices for the Comparable Treasury Issue (expressed in each case as a percentage of its principal amount) quoted in writing to the Trustee by the Reference Treasury Dealer at 5:00 p.m., New
York City time, on the third business day before the date of redemption. 
 In the event of redemption of this Security in part
only, a new Security or Securities of this series for the unredeemed portion hereof will be issued in the name of the holder hereof upon the cancellation hereof. 
 In case an Event of Default with respect to the Securities of this series shall have occurred and be continuing, the principal of all of the Securities of this series may be declared, and upon such
declaration shall become, due and payable, in the manner, with the effect and subject to the conditions provided in the Indenture. 
 The Indenture contains provisions for defeasance at any time of the entire indebtedness of the Securities of this series upon compliance by the Company with certain conditions set forth therein.

 The Indenture permits, with certain exceptions as therein provided, the Company and the Trustee, with the consent of the
holders of not less than a majority in aggregate principal amount of the Securities of each series affected at the time Outstanding, as defined in the Indenture, to execute supplemental indentures for the purpose of adding any provisions to,
changing in any manner or eliminating any of the provisions of the Indenture or of any supplemental indenture or of modifying in any manner the rights of the holders of the Securities. The Indenture also contains provisions permitting the holders of
a majority in aggregate principal amount of the Securities of all series at the time outstanding affected thereby, on behalf of the holders of the Securities of such series, to waive any past default in the performance of any of the covenants
contained in the Indenture, or established pursuant to the Indenture with respect to such series, and its consequences, except a default in the payment of the principal of or premium, if any, or interest on any of the Securities of such series,
which default may be waived by the unanimous consent of the holders affected. Any such consent or waiver by the registered holder of this Security (unless revoked as provided in the Indenture) shall be conclusive and binding upon such holder and
upon all future holders and owners of this Security and of any Security issued in exchange herefor or in place hereof (whether by registration of transfer or otherwise), irrespective of whether or not any notation of such consent or waiver is made
upon this Security. 

  
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 Upon an Event of Default, the Trustee or the holders of not less than 25% in principal
amount of the outstanding Securities of this series may declare the principal of all of the Securities of this series to be immediately due and payable; and upon any such declaration such principal amount of and the accrued interest on all of the
Securities of this series shall become immediately due and payable. 
 No reference herein to the Indenture and no provision of
this Security or of the Indenture shall alter or impair the obligation of the Company, which is absolute and unconditional, to pay the principal of and premium, if any, and interest on this Security at the time and place and at the rate and in the
money herein prescribed. 
 As provided in the Indenture and subject to certain limitations therein set forth, this Security is
transferable by the registered holder hereof on the Security Register of the Company, upon surrender of this Security for registration of transfer at the office or agency of the Company designated for such purpose in the City of St. Paul, Minnesota,
accompanied by a written instrument or instruments of transfer in form satisfactory to the Company and the Trustee duly executed by the registered holder hereof or its attorney duly authorized in writing, and thereupon one or more new Securities of
authorized denominations and for the same aggregate principal amount and series will be issued to the designated transferee or transferees. No service charge will be made for any such transfer, but the Company may require payment of a sum sufficient
to cover any tax or other governmental charge payable in relation thereto. 
 Prior to due presentment for registration of
transfer of this Security, the Company, the Trustee, any paying agent and any Security Registrar may deem and treat the registered holder hereof as the absolute owner hereof (whether or not this Security shall be overdue and notwithstanding any
notice of ownership or writing hereon made by anyone other than the Security Registrar) for the purpose of receiving payment of or on account of the principal hereof and premium, if any, and interest due hereon and for all other purposes, and
neither the Company nor the Trustee nor any paying agent nor any Security Registrar shall be affected by any notice to the contrary. 
 No recourse shall be had for the payment of the principal of or the interest on this Security, or for any claim based hereon, or otherwise in respect hereof, or based on or in respect of the Indenture,
against any incorporator, stockholder, officer or director, past, present or future, as such, of the Company or of any predecessor or successor corporation, whether by virtue of any constitution, statute or rule of law, or by the enforcement of any
assessment or penalty or otherwise, all such liability being, by the acceptance hereof and as part of the consideration for the issuance hereof, expressly waived and released. 

  
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 [If this Note is to be issued as a Global Security, insert This Global Security is
exchangeable for Securities in certificated form only under certain limited circumstances set forth in the Indenture.] The Securities of this series are issuable in registered form without coupons in denominations of $2,000 and integral multiples of
$1,000 in excess thereof. As provided in the Indenture and subject to certain limitations herein and therein set forth, Securities of this series so issued are exchangeable for a like aggregate principal amount of Securities of this series of a
different authorized denomination, as requested by the holder surrendering the same. 
 All terms used in this Security which
are defined in the Indenture shall have the meanings assigned to them in the Indenture. 
 This Security shall be governed by
and construed in accordance with the laws of the State of New York applicable to agreements made and performed in said state. 

  
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