Document:

exv10w1

 

Exhibit 10.1

SERVICE AGREEMENT

     This Service Agreement (“Agreement”) is made as of March 1, 2005 by and between VENTIV PHARMA
SERVICES, LLC, a New Jersey limited liability company (“Ventiv”) and CONNETICS CORPORATION, a
Delaware corporation, having an office at 3160 Porter Drive, Palo Alto, California 94304
(“Client”). Ventiv and Client may each be referred to in this Agreement as a “Party” and
collectively as the “Parties.”

     1.   The Services. Ventiv will provide Client with a field force consisting of:
fifty (50) sales representatives (the “Ventiv Sales Representatives”) who shall detail Client’s
Products (as defined in Exhibit B), five Ventiv District Sales Managers, one Project Manager on a
non-exclusive basis (i.e., the Project Manager may also work on matters for other Ventiv clients),
and one National Business Director on a non-exclusive basis (i.e., the National Business Director
may also work on matters for other Ventiv clients) (collectively, the “Project Team”). In
connection with the promotion of Client’s Products, Ventiv shall provide the following services
(collectively, the “Services”):

     (a) Implementation. 

     (i) Recruit and train the Project Team. Ventiv shall be responsible for recruiting and
re-recruiting (replacing) all Ventiv Sales Representatives and Ventiv District Sales
Managers. Client shall have a right to participate in the selection of the Ventiv District
Sales Managers and Sales Representatives. If Client elects to participate in the final
selection of the Ventiv District Sales Managers and Sales Representatives, Client must
approve or disapprove candidates within five business days after Ventiv submits the
candidate to Client for review. Ventiv will exercise commercially reasonable efforts to
recruit from a diverse candidate base. A qualified candidate for Sales Representative shall
meet the following minimum qualifications: four-year college degree (B.A., B.S., or
equivalent); minimum one year outside sales experience. Unless otherwise approved by
Client, (A) a minimum of 50% of the Ventiv Sales Representatives must have applicable
pharmaceutical or biotechnology sales experience (contingent upon Client approving higher
salaries for the Ventiv Sales Representatives (as a pass-through cost), as needed to
maintain the minimum 50%, and (B) a qualified candidate for the District Sales Manager shall
meet the following minimum qualifications: four-year college degree (B.A., B.S., or
equivalent); minimum two years outside sales experience, minimum one year previous
management experience.

     (ii) Develop program procedures,

     (iii) Customize processes,

     (iv) Establish performance parameters.

     (b) Deployment. As used in this Agreement, “Deployment” or “Deployment Date” shall
mean the date the Ventiv Sales Representatives begin detailing the Products. The Parties
anticipate that the Deployment Date will be April 18, 2005. Ventiv shall be responsible for:

     (i) salary, benefits (management of incentive compensation plan) and

 

 

deployment of Ventiv Sales Representatives (including providing sales force automation
equipment),

     (ii) salary and benefits for full-time Ventiv District Sales Managers, National
Business Director (non-exclusive) and Project Manager (non-exclusive),

     (iii) turnover training and recruiting (which will be billed to Client as a
pass-through expense (see Exhibit A)),

     (iv) providing company cars for Ventiv Sales Representatives and Ventiv District Sales
Managers,

     (vi) Ventiv’s office costs/operational supplies,

     (vii) initial sales territory alignment,

     (viii) Ventiv Sales Representative sample storage units, and

     (ix) Sample audits and reconciliation as requested by Client.

     (x) Delivery of reports as set forth in Section 1(c) below.

     (xi) Arranging for storage sample and distribution of promotional
material (subject to the Parties agreement with Promotech, Inc.).

     (xii) Arranging for shipment of samples and promotional material
(subject to the Parties agreement with Promotech, Inc.).

     (c) Reports. Each month (or at Client’s written request), Ventiv shall provide to
Client all sales call activity reports that document the detailing and sampling by the Project Team
(as set forth in Exhibit C attached hereto). The format of activity and performance reports will
be mutually agreed upon. In addition, upon Client’s written request, Ventiv shall provide Client
with (i) standard reports, as long as Client provides Ventiv with all required information and
data, and (ii) any customized or “non-standard” reports. Client shall pay Ventiv Two Hundred and
Fifty Dollars ($250) per hour for preparing such customized or “non-standard” reports. For
purposes of this Agreement, “standard” reports shall include the following:

	 	•  	Call and Detail Report
	 
	 	•  	Sample Report
	 
	 	•  	Reach and Frequency Report
	 
	 	•  	Days in Field Report
	 
	 	•  	Performance Report by Product
	 
	 	•  	Expense Report (GELCO system)
	 
	 	•  	Others as agreed to by the Parties

Client shall have the right to assign one or more employees of Client to accompany Ventiv Sales
Representatives to monitor performance under this Agreement; provided Client or its employee(s)
provide at least three days prior written notice and there is no interference with the performance
of the Services performed by the Ventiv Sales Representative.

     (d) Sample Accountability. Ventiv shall be responsible for implementing a sample
accountability program on Client’s behalf, consistent with applicable federal and state laws,
regulations, and guidelines, including but not limited to the Prescription Drug Marketing Act
(“PDMA”) and its implementing regulations. The Project Team must comply with all

2

 

applicable laws, regulations and guidelines. Unless otherwise agreed in writing, Client shall
be responsible for production and shipment of sample and literature to Ventiv’s designated
warehouse. Ventiv will be responsible for shipping samples to the Ventiv Sales Representatives in
accordance with PDMA guidelines. Client shall confirm and provide documentation for such shipments
to Ventiv within twenty-four hours. Ventiv will reconcile such information, including but not
limited to sample inventory, and notify Client of any discrepancies. Client will investigate any
discrepancies. Client will validate a current list of licensed practitioners and validate
additions and changes. Client is responsible for taking all action required or suggested by the
Food and Drug Administration (“FDA”), including but not limited to: reporting of adverse events,
confirming all returned samples and, where applicable, notifying the FDA, and all supplemental
communications with respect to any of the above.

     (e) Product Literature; Promotion. Ventiv shall be responsible for (i) ensuring that
only Product Literature and samples approved by Client are distributed by the Ventiv Sales
Representatives; (ii) promoting the Products in a manner that complies in all respects with
applicable federal and state law, including but not limited to, the Federal, Food, Drug, and
Cosmetic Act (“FDCA”) and PDMA; (iii) cooperating with Client, at Client’s expense, to conduct any
necessary recalls of Product samples or Product Literature.

     (f) The Project Team (except for the National Business Director and the Project Manager) will
be dedicated and as such, will only promote the Products. Ventiv will promote the Products in the
United States of America (the “Territory”). Ventiv with assistance from Client’s General Manager
of the PCP/PED Franchise (the “General Manager”) shall manage, supervise, and evaluate the
performance of the Ventiv Sales Representatives and Ventiv District Sales Managers in accordance
with the responsibilities and duties identified below. Subject to Section 6, Ventiv’s District
Sales Managers shall meet with the Client’s General Manager on a regular schedule, to be mutually
agreed.

     Sales Representatives shall:

	 	•  	Generate sales within an assigned territory
	 
	 	•  	Plan and organize territory to meet call audience, including: (i) a call activity
minimum, and (ii) attainment of monthly Reach and Frequency goals with respect to the
designated Call Audience (as defined in Section 3), both of which shall be mutually
agreed upon by the Parties in writing
	 
	 	•  	Make sales presentations (details)
	 
	 	•  	Maintain and update current and prospective target physician profiles and generate
complete and consistent call notes on sales interactions
	 
	 	•  	Participate in all training and sales meetings including POA. The inability of a
Sales Representative to complete training is cause for immediate separation from
current deployment
	 
	 	•  	Maintain a professional image for Client and Client’s Products
	 
	 	•  	Maintain sample inventories, distribute samples, comply with sample accountability
procedures and policies, comply with PDMA, comply with applicable local, state, and
federal regulations
	 
	 	•  	Report all field activities and expenditures in a manner that is timely, accurate,
and honest, and in accordance with policies and procedures for the applicable reporting

3

 

	 	   	systems.
	 
	 	•  	Comply with promotional programs, and proper use of promotional materials and
promotional expense budgets

     District Sales Managers shall:

	 	•  	Coordinate closely with the Client’s General Manager of the PCP/PED Franchise,
including regular conference calls, weekly contact reports, and other activities
requested by the General Manager
	 
	 	•  	Recruit, interview, and select Sales Representatives
	 
	 	•  	Use commercially reasonable efforts to fill an empty territory within 30 days,
unless agreed upon by Client
	 
	 	•  	Make regular field visits, with a minimum of one every quarter: to develop and
motivate Sales Representatives for attainment of sales objectives; to assess and
monitor field activity and work schedules; to monitor and manage field reporting by
Sales Representatives, including call and sample reporting
	 
	 	•  	Monitor compliance with promotional programs, and proper use of promotional
materials and promotional expense budgets
	 
	 	•  	Monitor compliance with PDMA and sample accountability procedures
	 
	 	•  	Handle all performance reviews, personnel issues, discipline and termination of
Sales Representatives
	 
	 	•  	Work closely with Client General Manager providing regular reports and updates
including but not limited to monthly field contact plan, personnel development plans,
call and routing performance, business development plans.

2.   The Products; Right to Sell; Market. Ventiv shall promote the Products set forth on
Exhibit B under trademarks owned by or licensed to Client. Client represents to Ventiv that Client
either owns all of the Products or Client has all lawful authority necessary to market and sell the
Products in the Territory. This Agreement does not constitute a grant to Ventiv of any property
right or interest in the Products or the trademarks owned by or licensed to Client and/or any other
intellectual property rights which Client owns now or in the future. Ventiv recognizes the
validity of and the title to all of Client’s owned or licensed trademarks, trade names and trade
dress in any country in connection with the Products, whether registered or not. Client represents
to Ventiv that neither those trademarks, trade names and trade dress, nor the promotion of the
Products by Ventiv, infringes on any intellectual property or product marketing rights of any other
person.

3.   Client Responsibilities. Except as otherwise agreed, Client shall be responsible for:

     (a) identifying and validating the Call Audience (as defined below) (except for potential
additional calls identified by the Ventiv Sales Representatives and approved by Client),

     (b) validating state licensure,

     (c) preparing all training materials and participation in training the Project Team,

4

 

     (d) producing samples of the Products and Product literature,

     (e) providing Ventiv with a data feed of activity and sales data to allow Ventiv to prepare
internal reports, and

     (f) providing Ventiv with all Product literature and promotion material.

The “Call Audience” means a licensed primary care physician or pediatrician or others whom Client
identifies (in writing) as potential physicians to whom the Ventiv Sales Representatives shall
detail the Products. The Call Audience may be changed by Client on a quarterly basis. Each Ventiv
Sales Representative will have a list representing that person’s designated Call Audience.

4.   Ventiv Compensation. Client shall pay Ventiv for the Services as set forth in Exhibit
A.

5.   Confidentiality; Ownership of Property.

     (a) During the performance of the Services, each Party may learn confidential, proprietary,
and/or trade secret information of the other Party (“Confidential Information”). The Party
disclosing Confidential Information shall be referred to as the “Disclosing Party” and the Party
receiving Confidential Information shall be referred to as the “Receiving Party.” Confidential
Information means any information, unknown to the general public, which the Disclosing Party
discloses to the Receiving Party under this Agreement. Confidential Information includes, without
limitation, technical, trade secret, commercial and financial information about either Party’s:
(i) research or development; (ii) marketing plans or techniques, contacts or customers; (iii)
organization or operations; (iv) business development plans (i.e., licensing, supply, acquisitions,
divestitures or combined marketing); (v) Products, licenses, trademarks, patents, other types of
intellectual property or any other contractual rights or interests (including without limitation
processes, procedures and business practices involving trade secrets or special know-how), and (vi)
in the case of Ventiv, the names and work assignments of Ventiv employees. The Receiving Party
shall neither use nor disclose Confidential Information from the Disclosing Party for any purpose
other than is specifically allowed by this Agreement.

     (b) Upon the expiration or termination of this Agreement, the Receiving Party shall return to
the Disclosing Party all tangible forms of Confidential Information, including any and all copies
and/or derivatives of Confidential Information made by either Party or their employees as well as
any writings, drawings, specifications, manuals or other printed or electronically stored material
based on or derived from, Confidential Information. Any material or media not subject to return
must be destroyed. The Receiving Party shall not disclose to third parties any Confidential
Information or any reports, recommendations, conclusions or other results of work under this
Agreement without prior consent of an officer of the Disclosing Party. The obligations set forth
in this Section 5, including the obligations of confidentiality and non-use shall be continuing and
shall survive the expiration or termination of this Agreement and will continue for a period of two
years.

5

 

     (c) The obligations of confidentiality and non-use set forth in this Agreement shall not apply
to the following: (i) Confidential Information at or after such time that it is or becomes
publicly available through no fault of the Receiving Party; (ii) Confidential Information that is
already independently known to the Receiving Party as shown by prior written records; (iii)
Confidential Information at or after such time that it is disclosed to the Receiving Party by a
third party with the legal right to do so; (iv) Confidential Information required to be disclosed
pursuant to judicial process, court order or administrative request, provided that the Receiving
Party shall so notify the Disclosing Party sufficiently prior to disclosing such Confidential
Information as to permit the Disclosing Party to seek a protective order.

     (d) All materials and documents supplied to either Party during the Term of this Agreement,
including but not limited to sales force automation software, report designs, and sales training
materials shall be the sole and exclusive property of the originator of those materials and
developments. Each Party agrees to hold all such property and developments, confidential in
accordance with this Section 5 of the Agreement.

     6.   Independent Contractors. Ventiv and its directors, officers, and the persons
providing Services are at all times independent contractors with respect to Client, and shall not
be deemed employees of Client. In particular, Ventiv shall be responsible for management of all
employer obligations in connection with Ventiv employees who perform the Services. Ventiv
employees shall remain exclusively under the direct authority and control of Ventiv, although
Client shall be involved in providing training and direction to the Ventiv Sales Representatives
and Project Team. Ventiv shall not be responsible for any cost, however, attributable to: (a) any
actions by Client that caused a person provided by Ventiv to perform services under this Agreement
to be reclassified as an employee of Client, (b) any unlawful or discriminatory acts of Client, or
(c) language in any Client benefit plan that is deemed to extend coverage to persons provided by
Ventiv to perform Services based on their activities under this Agreement.

7.   Ventiv Personnel.

     (a) Except as set forth in Section 8 below, Client may not employ or retain any member of the
Project Team during the Term of this Agreement or within one year after the end of the Term (or any
Additional Term) without the prior written approval of Ventiv, which may be withheld by Ventiv in
its sole and absolute discretion.

     (b) Client agrees during the Term (or any Additional Term) and for the one year period
thereafter not to: (i) provide information (including name and address) concerning any Ventiv
employee providing services under this Agreement to any third party which provides or proposes to
provide contract sales services to Client, or (ii) assist actively in any other way such a third
party in employing or retaining a Ventiv employee who provides
services under this Agreement. [**]

8.   Block Conversion and Selective Hiring; Related Fees. Client may hire Sales
Representatives and Ventiv District Managers of the Project Team only in accordance with the
following:

** Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions.

6

 

     (a) Selective Hiring, Recruitment. Client may solicit, employ or retain one or more
Ventiv Sales Representatives or Ventiv District Sales Managers representing less than 25% of the
entire Project Team providing Services under this Agreement (“Selective Hiring”), any time after
such members of the Project Team have been Deployed pursuant to this Agreement. Client shall give
30 days’ advance notice to Ventiv of any Selective Hiring. Should there be Selective Hiring by
Client, Ventiv will backfill the respective position so as to maintain the previously agreed upon
number of members of the Project Team.

     (b) Block Conversion. Client may solicit, employ or retain at any one time Ventiv
Sales Representatives and Ventiv District Sales Managers representing in excess of 25% of the
entire Project Team providing Services under this Agreement (a “Block Conversion”) provided that:
(i) such hiring may not occur before the first anniversary of the Deployment Date, and (ii) Client
may not hire any Ventiv Sales Representatives or Ventiv Sales District Managers pursuant to this
Section 8(b) who commenced providing Services to Client pursuant to this Agreement less than one
year before the Block Conversion, and (iii) Client must provide at least 90 days’ prior written
notice to Ventiv of any Block Conversion.

     (c) Fees for Selective Hiring and Block Conversion. If Client implements either a
Selective Hiring or a Block Conversion during the Term (or any Additional Term), Client shall pay
to Ventiv a finder’s fee according to the following table:

[**]

In addition to the above fees, Client understands and agrees that if Client implements either a
Selective Hiring or a Block Conversion, it shall pay to Ventiv the Termination Expenses described
in Exhibit A.

     (d) If Client implements either a Block Conversion or a Selective Hiring, any and all copies
of the Ventiv “Selling Skills” or any other proprietary training module which had been provided to
members of the Project Team will be immediately returned to Ventiv, it being understood and agreed
that the Ventiv Selling Skills Training Module constitutes valuable and proprietary information of
Ventiv and is subject to the confidentiality obligations set forth in Section 5 of this Agreement.
Within five days after implementing either a Block Conversion or a Selective Hiring, Client shall
take all commercially reasonable steps to ensure that the newly converted member(s) of the Project
Team return to Ventiv any and all copies of the Ventiv Selling Skills Training Module which had
been in their possession.

9.   Indemnification

[**]

7

 

[**]

10.   Term. The Agreement shall be in effect as of March 1, 2005 and shall remain in full
force and effect through December 31, 2006. This Agreement will renew for additional periods of
one year each (each an “Additional Term”), upon written agreement by the Parties to be executed at
least 60 days before the end of the Term. Ventiv’s compensation for any Additional Term must be
agreed upon and set forth in the written agreement between the Parties.

11.  
Termination. [**]

[**]

	 	•  	[**]

** Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions.

8

 

	 	•  	[**]

[**]

[**]

[**]

12.   Miscellaneous

     (a) Each Party represents to the other that the execution, delivery and performance of this
Agreement by such Party has been duly authorized by all requisite corporate action; that the
Agreement constitutes the legal, valid, and binding obligation of such Party, enforceable in
accordance with its terms (except to the extent enforcement is limited by bankruptcy, insolvency,
reorganization or other laws affecting creditors’ rights generally and by general principles of
equity); and that this Agreement and performance under this Agreement does not violate or
constitute a breach under any organizational document of such Party or any contract, other form of
agreement, or judgment or order to which such Party is a party or by which it is bound.

     (b) Each Party undertakes to maintain appropriate insurance in commercially reasonable amounts
with financially capable carriers, including in the case of Client product liability insurance in
the amount [**]. Each Party shall use its best efforts to name the other Party
as an additional insured on all liability insurance coverage. In addition, upon written request,
each Party will provide the other with evidence of coverage complying with this Section.

     (c) Neither Ventiv nor Client may assign this Agreement or any of its rights, duties or
obligations under this Agreement without the other Party’s prior written consent, provided,
however, that either Ventiv or Client may assign its rights, duties and obligations as part of an
acquisition of Ventiv or Client, as the case may be, so long as the acquirer (i) is a financially
capable business entity, and (ii) expressly assumes in writing those rights, duties and obligations
under this Agreement and this Agreement itself.

** Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions.

9

 

     (d) This Agreement supersedes all prior arrangements and understandings between parties
related to the subject matter of this Agreement, including
specifically the Letter of Intent dated March 1, 2005, as it may have been amended or extended from time to time prior to the execution of
this Agreement.

     (e) Noncompliance with the obligations of this Agreement due to a state of force majeure, the
laws or regulations of any government, regulatory or judicial authority, war, civil commotion,
destruction of facilities and materials, fire, flood, earthquake or storm, labor disturbances,
shortage of materials, failure of public utilities or common carriers, and any other causes beyond
the reasonable control of the applicable Party, shall not constitute a breach of contract.

     (f) If any provision of this Agreement is finally declared or found to be illegal or
unenforceable by a court of competent jurisdiction, both Parties shall be relieved of all
obligations arising under such provision, but, if capable of performance, the remainder of this
Agreement shall not be affected by such declaration or finding.

     (g) This Agreement, including any attachments or exhibits entered into pursuant to this
Agreement, contains all of the terms and conditions of the agreement between the Parties and
constitutes the complete understanding of the Parties with respect to the subject matter of this
Agreement. No modification, extension or release from any provision of this Agreement shall be
effective unless it is in writing signed by the other Party and specifically described as an
amendment or extension of this Agreement.

     (h) This Agreement shall be construed according to the laws of the State of New Jersey and any
action brought by either Ventiv or Client in connection with this Agreement shall be brought in the
state or federal courts located in the State of New Jersey.

     (i) This Agreement may be executed in any number of counterparts, each of which, when
executed, shall be deemed to be an original and all of which together shall constitute one and the
same document.

     (j) Any notices required or permitted under this Agreement shall be given in person or sent by
internationally recognized air courier (e.g., Federal Express, DHL, etc.) or by U.S. Postal Service
first class and certified, to:

Ventiv:

Ventiv Pharma Services, LLC

200 Cottontail Lane

Somerset, New Jersey 08873

Attention: Terrell G. Herring, President

10

 

with a copy to:

David Blatteis

Norris, McLaughlin & Marcus, P.A.

721 Route 202-206

P.O. Box 1018

Somerville, New Jersey 08876-1018

     Client:

Connetics Corporation

3160 Porter Drive

Palo Alto, California 94304

Attention: Michael Miller, Chief Commercial Officer

with a copy to:

Katrina Church

General Counsel

Connetics Corporation

3160 Porter Drive

Palo Alto, California 94304

or to such other address or to such other person as one Party may designate by written notice given
to the other from time to time during the term of this Agreement.

///

///

///

///

///

///

///

///

///

[Balance of Page Intentionally Blank]

///

///

///

///

///

///

///

///

///

11

 

     WHEREFORE, the Parties have caused this Agreement to be executed by their duly authorized
representatives.

	 	 	 	 	 
	 	VENTIV PHARMA SERVICES, LLC

 	 
	 	By:  	/s/ Terrell E. Herring
 	 
	 	 	Name:  	Terrell E. Herring 	 
	 	 	Title:  	President & COO 	 
	 
	 	Date: 12 April 2005

	 	 	 	 	 
	 	CONNETICS CORPORATION

 	 
	 	By:  	/s/ Greg Vontz
 	 
	 	 	Greg Vontz 	 
	 	 	President 	 
	 
	 	Date: 12 April 2005

12

 

EXHIBIT A

COMPENSATION

Daily Rate, Incentive
Fees, Pass-Through Costs, And Termination Expenses

[**]

** Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions.

13

 

[**]

** Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions.

14

 

[**]

** Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions.

15

 

[**]

** Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions.

16

 

[**]

** Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions.

17

 

EXHIBIT B

List of Client’s Products*

	 	 	 	 	 	 	 	 	 
	 
	 	Marketed Name	 	 	NDC Number	 	 	Product Size	 
	 	Olux®Foam (clobetasol propionate), 0.05%

	 	 	63032-031-00
	 	 	100 gram	 
	 	Olux®Foam (clobetasol propionate), 0.05%

	 	 	63032-031-50
	 	 	50 gram	 
	 	Luxíq® Foam (betamethasone valerate), 0.12%

	 	 	63032-021-01
	 	 	150 gram	 
	 	Luxíq® Foam (betamethasone valerate), 0.12%

	 	 	63032-021-00
	 	 	100 gram	 
	 	Luxíq® Foam (betamethasone valerate), 0.12%

	 	 	63032-021-50
	 	 	50 gram	 
	 	EvoclinTM Foam (clindamycin phosphate), 1%

	 	 	63032-061-00
	 	 	100 gram	 
	 	EvoclinTM Foam (clindamycin phosphate), 1%

	 	 	63032-061-50
	 	 	50 gram	 
	 

	*	 	The term “Products” does not include Product samples.

18

 

EXHIBIT C

SALES REPORTS AND ANALYSIS

[**]

** Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions.

19

 

[**]

** Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions.

20

 

[**]

** Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions.

21exv10w2

 

Exhibit 10.2

SUBLEASE AGREEMENT

I.

DEFINED TERMS

	 	 	 	 	 	 	 
	Basic Rent:

	 	Months
	 	Monthly Basic Rent

	 

	 	1-12
	 	$	24,308.75*	 
	

	 	13-24
	 	$	25,281.10	 
	

	 	25-36
	 	$	26,253.45	 
	

	 	37-48
	 	$	28,198.15	 
	

	 	49-60
	 	$	29,170.50	 

* The monthly basic rent rate set forth above for months
1-12 shall apply to the period commencing on the
Commencement Date and ending on December 31, 2006

	 	 	 
	Broker:

	 	CRESA Partners (representing both Sublessor and Sublessee)
	 
	 	 
	Building:

	 	Buildings E, F and G located at 1841 Page Mill Road, Palo
Alto, California
	 
	 	 
	Effective Date:

	 	August 9, 2004
	 
	 	 
	Expiration Date:

	 	December 31, 2010
	 
	 	 
	Landlord:

	 	Interval Research Corporation, a Washington corporation
	 
	 	 
	Master Lease:

	 	That certain Office Building Lease dated as of August 18,
1999 by and between Page Mill Road Properties Inc., the
predecessor-in-interest to Landlord, as landlord, and
Incyte Pharmaceuticals, Inc., the predecessor-in-interest
to Sublessor, as tenant, as amended by that certain First
Amendment to the Lease dated as of July 19, 2000 (the
“First Amendment”) by and between Landlord and Incyte
Genomics, Inc., the predecessor-in-interest to Sublessor
	 
	 	 
	Permitted Uses:

	 	The uses permitted in Section 1.16 of the Master Lease,
and for no other uses
	 
	 	 
	Premises:

	 	Improved real property, as more particularly described in
the Master Lease attached hereto as Exhibit A, consisting
of approximately 59,056 rentable square feet
	 
	 	 
	Commencement Date:

	 	The earlier of (i) January 1, 2006, or (ii) the date
Sublessee commences business operations in the Sublet
Space

1.

 

	 	 	 
	Letter
of Credit:

	 	$145,852.50
	 

	 	 
	Sublessee:

	 	Connetics Corporation, a Delaware corporation
	 
	 	 
	Sublessee’s Address:

	 	Prior to January 1, 2005:
	 
	 	 
	

	 	Connetics Corporation
	

	 	3290 West Bayshore Road
	

	 	Palo Alto, CA 94303
	

	 	Attn: Christopher T. Holman,
	

	 	Director of Facilities and Production Planning
	 
	 	 
	

	 	On and after January 1, 2005:
	 
	 	 
	

	 	Connetics Corporation
	

	 	3160 Porter Drive
	

	 	Palo Alto, CA 94304
	

	 	Attn: Christopher T. Holman,
	

	 	Director of Facilities and Production Planning
	 
	 	 
	Sublessee’s Share:

	 	32.93% with respect to the Building and 10.66% with
respect to the Development
	 
	 	 
	Sublessor:

	 	Incyte Corporation, a Delaware corporation
	 
	 	 
	Sublessor’s Address:

	 	Incyte Corporation
	

	 	Experimental Station
	

	 	Route 141 and Henry Clay Road
	

	 	Building 336
	

	 	Wilmington, DE 19880
	

	 	Attn: General Counsel
	 
	 	 
	

	 	with a copy to:
	 
	 	 
	

	 	Incyte Corporation
	

	 	Experimental Station
	

	 	Route 141 and Henry Clay Road
	

	 	Building 336
	

	 	Wilmington, DE 19880
	

	 	Attn: Chief Financial Officer
	 
	 	 
	Sublet Space:

	 	That portion of the Premises, as more particularly
described in the Sublet Space Floor Plan attached hereto
as Exhibit B, consisting of approximately 19,447 rentable
square feet located on the first and second floors of
Building E
	 
	 	 
	Sublease Term:

	 	Sixty (60) months

2.

 

	 	 	 
	Exhibits:

	 	Exhibit A — Master Lease
	

	 	Exhibit B — Sublet Space Floor Plan
	

	 	Exhibit C — List of FF&E
	

	 	Exhibit D — Determination of Prevailing Market Rent

II.

     THIS SUBLEASE AGREEMENT (this “Sublease”) is entered as of the Effective Date by and between
Sublessor and Sublessee. Sublessor and Sublessee are each sometimes referred to in this Sublease
as a “Party” and collectively as “Parties.”

     THE PARTIES ENTER this Sublease on the basis of the following facts, understandings and
intentions:

     A. Sublessor is presently the lessee of the Premises pursuant to the Master Lease by and
between Landlord and Sublessor. A copy of the Master Lease, with all exhibits and addenda thereto,
is attached hereto as Exhibit A.

     B. Sublessor desires to sublease the Sublet Space to Sublessee and Sublessee desires to
sublease the Sublet Space from Sublessor on all of the terms, covenants and conditions hereinafter
set forth.

     C. All of the terms and definitions in the Defined Terms section of this Sublease are
incorporated herein by this reference. Capitalized terms used in this Sublease and not otherwise
defined herein shall have the meanings given to them in the Master Lease.

     NOW, THEREFORE, IN CONSIDERATION of the mutual covenants and promises of the Parties, the
Parties hereto agree as follows:

     1. Sublease Term.

          a. Commencement and Expiration of Sublease Term. The Sublease Term shall commence on
the Commencement Date and end on the Expiration Date. If for any reason Sublessor does not deliver
possession of the Sublet Space to Sublessee on or before January 1, 2006, then this Sublease shall
not terminate. Sublessor will have no liability for such failure to deliver the Sublet Space, but
the Basic Rent and Additional Rent due hereunder shall not commence until the date possession of
the Sublet Space is given to Sublessee. Sublessor shall sublease to Sublessee, and Sublessee shall
sublease from Sublessor the Sublet Space for the Sublease Term upon all of the terms, covenants and
conditions herein contained.

          b. Early Access. Prior to January 1, 2006 (but in no event earlier than July 1,
2005), Sublessee shall be permitted access to the Sublet Space for the sole purpose of performing
improvements and installing Sublessee’s equipment, furniture and other personal property, at
Sublessee’s sole cost and expense. In the event Sublessee desires such early access

3.

 

to the Sublet Space, Sublessee shall deliver written notice thereof to Sublessor no later than
thirty (30) days prior to the date Sublessee desires such access to the Sublet Space. The date
(which in no event shall be earlier than July 1, 2005) upon which Sublessor provides Sublessee such
early access to the Sublet Space pursuant to this Section 1.b shall be referred to herein as the
“Early Access Period Commencement Date.” The period from the Early Access Period Commencement Date
through the earlier of (i) December 31, 2005, or (ii) the date immediately preceding the date
Sublessee commences business operations in the Sublet Space shall be referred to herein as the
“Early Access Period.” Under no circumstances shall or may Sublessee conduct business in the
Sublet Space during the Early Access Period. All the terms and conditions of this Sublease
(including without limitation, Sublessee’s indemnity, insurance and maintenance and repair
obligations hereunder and Sublessee’s obligation hereunder to pay utilities and services and
Sublessee’s Share of Operating Expenses for the Building, Operating Expenses for the Common Areas
of the Development, and Transit Assessments for the Development) shall apply during the Early
Access Period, except that Sublessee shall not be obligated to pay Basic Rent during the Early
Access Period. Without limiting the generality of the foregoing, Sublessee shall be responsible
for repairing, at its cost, any damage to the Building or the Development arising out of or
resulting from Sublessee’s performance of any Alterations (as defined in the Master Lease) and/or
installation of equipment, furniture or other personal property during the Early Access Period.
Sublessee’s early access shall also be conditioned upon Sublessee’s not being in default hereunder
and the Parties having received the prior written consent of Landlord to this Sublease. Any
Alterations performed by Sublessee during the Early Access Period (or thereafter) shall be
performed in accordance with the terms of this Sublease (including, without limitation, the need to
obtain the prior written consent of Sublessor and Landlord thereto and Sublessee’s obligation to
pay any construction supervisory fees charged by Landlord and/or Sublessor in connection with such
Alterations). Without limiting the generality of the foregoing, the Parties agree that Sublessor
may withhold its consent to any Alterations which have not been approved by Landlord. With respect
to any Alterations that Sublessee proposes to make during the Early Access Period, Sublessor agrees
to request that Landlord undertake Landlord’s review of such Alterations concurrent with
Sublessor’s review of such Alterations; provided, however, Sublessee acknowledges that Landlord has
no obligation to agree to undertake such review concurrently, and therefore Sublessor makes no
representation or warranty to Sublessee that Landlord will agree to such concurrent review.
Sublessor further agrees that its written approval (or disapproval, as the case may be) of any
Alterations that Sublessee proposes to make during the Early Access Period shall be delivered to
Sublessee within seven (7) business days after Sublessor’s receipt of Landlord’s written approval
(or disapproval, as the case may be) of such Alterations. Sublessee, at its sole cost and expense
and in accordance with the terms of the Master Lease, shall be responsible for removing from the
Sublet Space upon the expiration or earlier termination of this Sublease any Alterations made by or
for the benefit of Sublessee and designated by Landlord to be removed pursuant to the Master Lease.

          c. Confirmation of Dates. At any time during the Sublease Term, Sublessor may deliver
to Sublessee a statement confirming the Early Access Period Commencement Date (if applicable) and
the Commencement Date, which statement (provided it accurately reflects such dates) Sublessee shall
execute and return to Sublessor within ten (10) days after Sublessee’s receipt thereof.

4.

 

     2. Condition of Sublet Space.

          a. Physical Condition. Sublessor shall deliver the Sublet Space with all plumbing,
electrical and HVAC systems within the Sublet Space in good working order and condition as of the
Early Access Period Commencement Date or the Commencement Date, whichever occurs first. As of the
Effective Date, Sublessee acknowledges that Sublessee shall have conducted Sublessee’s own
investigation of the Sublet Space and the physical condition thereof, including accessibility and
location of utilities, and improvements, which in Sublessee’s judgment affect or influence
Sublessee’s use of the Sublet Space and Sublessee’s willingness to enter this Sublease, and subject
to the first sentence of this Section 2.a, shall accept the Sublet Space in “AS IS” condition and
repair. Sublessee acknowledges that Sublessor has made no representations of any kind in
connection with improvements or physical conditions on, or bearing on, the use of the Sublet Space.
Sublessee shall rely solely on Sublessee’s own inspection and examination of such items and not on
any representations of Sublessor, express or implied. Without limiting the generality of the
foregoing, Sublessee acknowledges and agrees that Sublessor shall not provide any fiber access to
the Sublet Space other than any fiber access that may currently exist in the Sublet Space as of the
Effective Date. Subject to the first sentence of this Section 2.a, Sublessee further recognizes
and agrees that neither Sublessor nor Landlord shall be required to perform any work of
construction or alteration to the Sublet Space to ready the same for Sublessee’s occupancy.

          b. Further Inspection. Sublessee represents and warrants to Sublessor that, as of the
Effective Date, Sublessee has examined and inspected all matters with respect to taxes, income and
expense data, insurance costs, bonds, permissible uses, the Master Lease, zoning, covenants,
conditions and restrictions and all other matters which in Sublessee’s judgment bear upon the value
and suitability of the Sublet Space for Sublessee’s purposes. Sublessee has and will rely solely
on Sublessee’s own inspection and examination of such items, and not on any representations of
Sublessor, express or implied. By taking possession of the Sublet Space, Sublessee accepts the
Sublet Space in its existing condition, subject to all applicable zoning, municipal, county and
state laws, ordinances and regulations governing and regulating the use of the Development or any
part thereof, and any covenants, conditions or restrictions of record, including, without
limitation, the CC&Rs (as defined in Section 7.2 of the Master Lease), and accepts this Sublease
subject thereto and to all matters disclosed thereby. Sublessee acknowledges that neither
Sublessor nor its agent has made any representation or warranty, express or implied, as to the
present or future suitability of the Development or any part thereof for the conduct of Sublessee’s
business.

          c. Transfer of FF&E. Effective as of the Early Access Period Commencement Date or the
Commencement Date, whichever occurs first (the “FF&E Effective Date”), Sublessor transfers to
Sublessee, in consideration of the sum of One Hundred Twenty Thousand and 00/100 Dollars
($120,000.00) to be paid by Sublessee to Sublessor upon the FF&E Effective Date and as a condition
precedent to the effectiveness of such transfer, Sublessor’s right, title and interest in and to
the furniture, trade fixtures and equipment located in the Sublet Space as of the Effective Date
and identified on Exhibit B attached hereto and incorporated herein by this reference
(collectively, the “FF&E”). SUBLESSEE HEREBY ACKNOWLEDGES AND AGREES THAT THE FF&E IS USED AND
CONVEYED AND ACCEPTED “AS-IS” WITHOUT ANY WARRANTIES OR REPRESENTATIONS OF ANY

5.

 

KIND OR NATURE, INCLUDING, WITHOUT LIMITATION, AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WHETHER
EXPRESS OR IMPLIED, OR WHETHER WRITTEN OR ORAL, CONCERNING ANY AND ALL DEFECTS OF A PHYSICAL
NATURE, WHETHER IN MATERIAL OR WORKMANSHIP AND WHETHER OR NOT SUCH DEFECT WOULD BE VISIBLE OR
APPARENT UPON SUBLESSEE’S FULL INSPECTION AND EXAMINATION OF THE FF&E. Sublessee, at its sole cost
and expense, shall be responsible for repairing, maintaining and insuring (in accordance with the
terms of the Master Lease) the FF&E. In addition, Sublessee, at its sole cost and expense, shall
be responsible for removing the FF&E from the Sublet Space, in accordance with the terms of the
Master Lease, upon the expiration or earlier termination of this Sublease. In addition, Sublessee,
at its sole cost and expense, shall be responsible for any and all licensing, connection
requirements and maintenance fees and contracts associated with the FF&E.

     3. Sublease Subject to Master Lease.

          a. Inclusions. It is expressly understood, acknowledged and agreed by Sublessee that
all of the other terms, conditions and covenants of this Sublease shall be those stated in the
Master Lease except as excluded in Section 3.c herein. Whenever the word “Premises” is used in the
Master Lease, for purposes of this Sublease, the word “Sublet Space” shall be substituted.
Sublessee shall be subject to, bound by and comply with all of said Articles and Sections of the
Master Lease with respect to the Sublet Space and shall satisfy all applicable terms and conditions
of the Master Lease for the benefit of both Sublessor and Landlord, it being understood and agreed
that, for purposes of this Sublease, wherever in the Master Lease the word “Tenant” appears, the
word “Sublessee” shall be substituted, and wherever the word “Landlord” appears, for the purposes
of this Sublease, the word “Sublessor” shall be substituted; wherever the words “Tenant’s
Percentage Share” appears, for the purposes of this Sublease, the words “Sublessee’s Share” shall
be substituted; and that upon the breach by Sublessee of any of said terms, conditions or covenants
of the Master Lease incorporated into this Sublease or upon the failure of Sublessee to pay Rent or
otherwise comply with any of the provisions of this Sublease, Sublessor may, but shall not be
obligated to, exercise any and all rights and remedies granted to Landlord by the Master Lease. In
the event of any conflict between the terms of this Sublease and the terms of the Master Lease, the
terms of this Sublease shall control as between Sublessor and Sublessee. It is further understood
and agreed that Sublessor has no duty or obligation to Sublessee under the aforesaid Articles and
Sections of the Master Lease other than to maintain the Master Lease in full force and effect
during the Sublease Term; provided, however, that Sublessor shall not be liable to Sublessee for
any termination of the Master Lease prior to the Expiration Date which is not caused solely by the
fault or default of Sublessor. Whenever the provisions of the Master Lease incorporated as
provisions of this Sublease require the written consent of Landlord, said provisions shall be
construed to require the written consent of both Landlord and Sublessor. Sublessee hereby
acknowledges that it has read and is familiar with all the terms of the Master Lease, and agrees
that this Sublease is subordinate and subject to the Master Lease and that any termination of the
Master Lease shall likewise terminate this Sublease unless Landlord and Sublessee have entered into
a recognition and attornment agreement whereby Landlord has agreed to accept this Sublease as a
direct lease between Landlord and Sublessee.

6.

 

          b. Modification of Incorporated Provisions. The following provisions of the Master
Lease, which have been incorporated into this Sublease pursuant to Section 3.a above, shall be modified for purposes of this Sublease as follows: (i) as used in
Section 2.3 of the Master Lease, the term “Landlord” shall mean Landlord, not Sublessor; (ii) as
used in the sixth sentence of Section 10 of the Master Lease, the term “Landlord” shall mean
Landlord, not Sublessor; (iii) as used in the first and second sentences of Section 12.1 of the
Master Lease, the term “Landlord” shall mean Landlord, not Sublessor; (iv) as used in the fourth,
fifth and sixth sentences of Section 12.1 of the Master Lease, the term “Landlord” shall mean
Landlord and Sublessor; (v) as used in Section 15.2 of the Master Lease, the term “Landlord” shall
mean Landlord and Sublesssor; (vi) in the first and second sentences of Section 18.1.1 of the
Master Lease, the words “the Building” shall be deleted and replaced with the words “the Sublet
Space”; (vii) as used in Section 18.3 of the Master Lease, the term “Landlord” shall mean Landlord,
not Sublessor; (viii) as used in Section 19 of the Master Lease, (A) the term “Landlord” shall mean
Landlord, not Sublessor; (B) the term “Tenant” shall mean Sublessor, not Sublessee, and (C) the
term “Premises” shall mean the Premises; (ix) as used in Section 20 of the Master Lease, (A) the
term “Landlord” shall mean Landlord, not Sublessor, (B) the term “Tenant” shall mean Sublessor, not
Sublessee, and (C) the term “Premises” shall mean the Premises; and (x) as used in Section 32 of
the Master Lease, the term “Landlord” shall mean Landlord, not Sublessor. In addition, Sublessee
acknowledges and agrees that by incorporating Section 9 of the Master Lease into this Sublease
pursuant to Section 3.a above, Sublessee shall be obligated to pay all holdover rent payable by
Sublessor to Landlord under the Master Lease in the event of any holdover by Sublessee.

          c. Exclusions. The following Sections and portions of the Master Lease shall not be
incorporated into this Sublease: Sections 1.1, 1.2, 1.3, 1.4 as to the size of the rentable space,
1.6, 1.7, 1.8, 1.9, 1.10, 1.12, 1.13, 1.14, 1.15, 1.19, 1.20, 2.1, the first sentence of Section
2.2, Section 3, Sections 4.1, 4.2 and 4.3, Section 6, Section 8, the first five sentences of
Section 10, Section 12.2, Section 15.1, Section 23 (other than Section 23.4, which is incorporated
into this Sublease by this reference), the second, fourth and last sentences of Section 24, Section
45, Section 46, Section 49.5, Section 55, Exhibit B and Exhibit F.

          d. Time for Notice. The time limits provided for in the provisions of the Master
Lease for the giving of notice, making of demands, performance of any act, condition or covenant,
or the exercise of any right, remedy or option, are amended for the purposes of this Sublease by
lengthening or shortening the same in each instance by five (5) days, as appropriate, so that
notices may be given, demands made, or any act, condition or covenant performed, or any right,
remedy or option hereunder exercised, by Sublessor or Sublessee, as the case may be, within the
time limit relating thereto contained in the Master Lease. If the Master Lease allows only five
(5) days or less for Sublessor to perform any act, or to undertake to perform such act, or to
correct any failure relating to the Premises or the Lease, then Sublessee shall nevertheless be
allowed three (3) days to perform such act, undertake such act and/or correct such failure.
Notwithstanding the foregoing, in the event Landlord provides concurrent written notice to
Sublessor and Sublessee, which written notice copies both Parties, of any failure by Sublessee to
perform any act, or to undertake to perform such act, or to correct any failure relating to the
Premises or the Lease, then Sublessee shall be entitled to the same time limit provided for in the
provisions of the Master Lease for Sublessor to perform such act, undertake to perform such act
and/or correct such failure.

7.

 

     4. Performance by Sublessor; Status of Master Lease.

          a. Sublessor’s Performance Conditioned on Landlord’s Performance. Sublessee
recognizes that Sublessor is not in a position to render any of the services or to perform any of
the obligations required of Landlord by the terms of the Master Lease. Therefore, despite anything
to the contrary in this Sublease, Sublessee agrees that performance by Sublessor of Sublessor’s
obligations under this Sublease is conditioned on performance by Landlord of Landlord’s
corresponding obligations under the Master Lease, and Sublessor will not be liable to Sublessee for
any default of Landlord under the Master Lease. Sublessee will not have any claim against
Sublessor based on Landlord’s failure or refusal to comply with any of the provisions of the Master
Lease unless that failure or refusal is a result of Sublessor’s act or failure to act. Despite
Landlord’s failure or refusal to comply with any of those provisions of the Master Lease, this
Sublease will remain in full force and effect and Sublessee will pay the Basic Rent and additional
rent and all other charges provided for in this Sublease without any abatement, deduction or
setoff, except and then only to the extent Sublessor is entitled to and receives any abatement,
deduction or setoff under the express terms of the Master Lease. Except as expressly provided in
this Sublease, Sublessee agrees to be subject to, and bound by, all of the covenants, agreements,
terms, provisions, and conditions of the Master Lease applicable to the Sublet Space, as though
Sublessee was the Tenant under the Master Lease with respect to the Sublet Space.

          b. Obtaining Landlord’s Consent. Whenever the consent of Landlord is required under
the Master Lease, or whenever Landlord fails to perform its obligations under the Master Lease,
Sublessor agrees to use Sublessor’s reasonable, good faith efforts to obtain, upon Sublessee’s
written request and at Sublessee’s sole cost and expense, such consent or performance on behalf of
Sublessee.

     5. Rent.

          a. Basic Rent. Sublessee shall pay to Sublessor the Basic Rent in advance on the
first day of each month of the Sublease Term, commencing on the Commencement Date (with the Parties
acknowledging that, provided the terms and conditions of Section 15 below have been satisfied,
Basic Rent for the original Sublet Space for the months of January 2006, February 2006 and March
2006 during the Sublease Term and for the months of April 2010, May 2010, June 2010, July 2010,
August 2010, September 2010, October 2010, November 2010 and December 2010 during the Sublease Term
shall be paid pursuant to such Section 15 ). In the event the first day of the Sublease Term shall
not be the first day of a calendar month or the last day of the Sublease Term is not the last day
of the calendar month, the Basic Rent shall be appropriately prorated based on a thirty (30) day
month. In addition, in the event the Commencement Date occurs prior to January 1, 2006 (as a
result of Sublessee’s early access to the Sublet Space pursuant to Section 1.b above and
Sublessee’s commencement of business operations in the Sublet Space prior to January 1, 2006),
Basic Rent for the first full or fractional calendar month of the Sublease Term shall be paid by
Sublessee to Sublessor on the first day of the calendar month immediately following the
Commencement Date. By way of illustration of the foregoing, if the Commencement Date is October
15, 2005, Basic Rent, prorated in accordance with this Section 5.a, for the period from October 15,
2005 through October 31, 2005 would be paid by Sublessee to Sublessor on November 1, 2005,
concurrent

8.

 

with Sublessee’s payment to Sublessor of Basic Rent for the month of November 2005. All
installments of Basic Rent shall be delivered to Sublessor’s Address, or at such other place as
may be designated in writing from time to time by Sublessor, in lawful money of the United
States and without deduction or offset for any cause whatsoever.

          b. Additional Rental. Commencing on the Early Access Period Commencement Date or the
Commencement Date, whichever occurs first, Sublessee shall be responsible for all costs and
expenses of every kind and nature relating to the Sublet Space which may be imposed, at any time,
on Sublessor pursuant to the Master Lease (except for Basic Rent, as defined in the Master Lease)
including, but not limited to, Sublessee’s Share of all Operating Expenses (including Real Property
Taxes) for the Building and the Common Areas of the Development, Transit Assessments, and all costs
and expenses relating to Landlord’s ownership and operation of the Building and the Development,
and other additional rent (collectively, “Additional Rent”). As hereinafter used, “Rent” shall
include Basic Rent, all Additional Rent to be paid by Sublessee pursuant to this Section 5.b, and
all other amounts payable by Sublessee under this Sublease.

          c. Utilities and Services. Commencing on the Early Access Period Commencement Date or
the Commencement Date, whichever occurs first, Sublessee shall be responsible for any and all
water, gas, heat, light, power, sewer, electricity and other utilities or services supplied to the
Sublet Space, in addition to Sublessee’s Share of utilities for the Common Areas payable under
Section 5.b above. Sublessee shall contract directly with all utilities providers to receive
invoices directly (in Sublessee’s name) from such utilities providers for utilities consumed in the
Sublet Space. To the extent such utilities or services are not separately metered, Sublessee shall
pay the cost attributable to the Sublet Space, as determined by Sublessor, in Sublessor’s
reasonable discretion, within thirty (30) days after Sublessor’s delivery of an invoice therefor.
In addition, commencing on the Early Access Period Commencement Date or the Commencement Date,
whichever occurs first, Sublessee, at its sole cost and expense, shall be responsible for providing
all janitorial and trash collection services for the Sublet Space.

     6. Letter of Credit.

          a. Form of Letter of Credit. Upon execution of this Sublease, and as a condition
precedent to the effectiveness of this Sublease, Sublessee shall deliver to Sublessor an
irrevocable stand-by letter of credit in the amount of One Hundred Forty Five Thousand Eight
Hundred Fifty Two and 50/100 Dollars ($145,852.50) (the “Letter of Credit”) as credit enhancement
for Sublessee’s faithful performance of all terms, covenants and conditions of this Sublease and
not as a security deposit, as more particularly described in this Section 6. The Letter of Credit
shall be in form and substance and issued by a bank that is reasonably satisfactory to Sublessor.
Sublessor hereby confirms that Silicon Valley Bank is acceptable as the initial issuer of the
Letter of Credit. The Letter of Credit shall: (i) name Sublessor as beneficiary, (ii) be
effective upon the Early Access Period Commencement Date or the Commencement Date, whichever occurs
first, (iii) allow Sublessor to make partial and multiple draws thereunder up to the face amount
for the purposes permitted under this Section 6, (iv) require the issuing bank to pay to Sublessor
the amount of a draw upon receipt by such bank of a sight draft signed by Sublessor and presented
to the issuing bank, accompanied by

9.

 

Sublessor’s statement that said draw is being made in
accordance with the terms of this Section 6, and (v) provide that Sublessor can freely transfer the
Letter of Credit upon an assignment or other
transfer of its interest in this Sublease to the assignee or transferee without having to obtain
the consent of Sublessee or the issuing bank. Sublessee shall be responsible for all fees
associated with issuance of the Letter of Credit. Sublessor shall be entitled to draw upon the
Letter of Credit in accordance with this Section 6, or at any time within thirty (30) days prior to
the expiration date of the Letter of Credit unless Sublessee shall have delivered to Sublessor a
replacement Letter of Credit meeting the requirements of this Section 6 and with an expiration date
not less than twelve (12) months after the date of delivery. The Letter of Credit (or a
replacement thereof satisfactory to Sublessor) shall remain in effect until the Expiration Date
(i.e., December 31, 2010).

          b. Draws Under Letter of Credit. Sublessor shall have the right (but shall not be
obligated to) draw under the Letter of Credit to remedy any default by Sublessee in the performance
of its obligations under this Sublease, and/or to compensate Sublessor for any losses, costs,
liabilities or damages incurred by Sublessor as a result of Sublessee’s failure to perform its
obligations under this Sublease (collectively, “Losses”). In the event Sublessor draws under the
Letter of Credit pursuant to this subsection (b), Sublessor shall use or apply the proceeds of such
draw to remedy Sublessee’s default and to compensate Sublessor for Losses. If, despite the intent
of the Parties that the Letter of Credit not be considered a security deposit, a court of competent
jurisdiction determines that the Letter of Credit is in fact a security deposit, then Sublessee
hereby waives to the extent inconsistent with the foregoing any restriction on the uses to which
the proceeds of a draw under the Letter of Credit may be applied as contained in Section 1950.7(c)
of the California Civil Code and/or any successor statute, if applicable. If Sublessor uses or
applies the proceeds of a draw under the Letter of Credit pursuant to this Section 6, Sublessee
shall, within ten (10) business days after demand therefor, deposit cash or other collateral with
the issuing bank and as required by the issuing bank in an amount sufficient to restore the Letter
of Credit to the amount thereof in effect immediately prior to such draw, and Sublessee’s failure
to do so shall, at Sublessor’s option, be a non-curable default under this Sublease. If Sublessee
has performed all of its obligations under this Sublease, the Letter of Credit, or so much thereof
as has not theretofore been applied by Sublessor in accordance with this Section 6, shall be
returned, without payment of interest or other increment for their use, to Sublessee upon the
Expiration Date (i.e., December 31, 2010). No trust relationship is created herein between
Sublessor and Sublessee with respect to the Letter of Credit.

     7. Use. The Sublet Space is to be used for the Permitted Uses, and for no other
purpose or business without the prior written consent of Sublessor and Landlord. In no event shall
the Sublet Space be used for a purpose or use prohibited by the Master Lease.

     8. Indemnity

          a. Sublessee Indemnity. In addition to, and without limitation of, Sublessee’s
indemnity obligations under this Sublease incorporated by reference from the Master Lease pursuant
to Section 3.a above, Sublessee agrees to indemnify, protect, defend, with attorneys approved by
Sublessor in its reasonable discretion, and save and hold harmless Sublessor and its trustees,
directors, officers, agents and employees, harmless from and against any and all losses, costs,
liabilities, claims, damages and expenses, including, without limitation,

10.

 

reasonable attorneys’
fees and costs, and reasonable investigation costs, that may at the time be asserted against
Sublessor by (a) Landlord for failure of Sublessee to perform any of the
covenants, agreements, terms, provisions, or conditions contained in the Master Lease that
Sublessee is obligated to perform under the provisions of this Sublease, or (b) any person or
entity as a result of Sublessee’s failure to surrender possession of the Sublet Space in accordance
with the terms of this Sublease.

          b. Sublessor Indemnity. Sublessor agrees to indemnify, defend, and hold Sublessee and
Sublessee’s officers, directors and employees harmless from and against any investigation and
remediation costs to the extent arising from or arising out of the release, treatment, storage, use
or disposal of Hazardous Materials in the Building or the Development by Sublessor in violation of
Environmental Regulations. Sublessor’s indemnification obligations hereunder shall extend only to
actual, out-of-pocket remediation costs (including reasonable attorneys’ fees and investigation,
oversight and response costs) but shall not include consequential damages or incidental damages
such as lost profits or any loss of rental value of the Sublet Space suffered or allegedly suffered
by Sublessee or any of Sublessee’s agents, employees, officers, directors, trustees, contractors,
subcontractors, subtenants, assignees, licensees or invitees or anyone claiming under Sublessee.

          c. Survival. The provisions of this Section 8 will survive the expiration or earlier
termination of this Sublease.

     9. Right to Cure Sublessee’s Defaults. If Sublessee shall at any time fail to make
any payment or perform any other obligation of Sublessee under this Sublease, then Sublessor shall
have the right, but not the obligation, after the lesser of (i) five (5) days’ notice to Sublessee,
or (ii) the time within which Landlord may act on Sublessor’s behalf under the Master Lease, or
(iii) without notice to Sublessee in the case of any emergency, and without waiving or releasing
Sublessee from any obligations of Sublessee under this Sublease, to make such payment or perform
such obligation of Sublessee in such manner and to such extent as Sublessor shall reasonably deem
necessary. In exercising any such right, Sublessor shall have the right to pay any reasonable
incidental costs and expenses, employ attorneys and other professionals, and incur and pay
reasonable attorneys’ fees and other costs reasonably required in connection with such failure to
perform, and Sublessee shall pay to Sublessor, upon demand, all such reasonable costs, fees and/or
expenses paid or incurred by Sublessor, together with interest thereon at the Effective Rate set
forth in the Master Lease.

     10. Damage and Destruction. The following provisions shall apply with respect to any
damage or destruction of the Sublet Space:

          a. Termination of Master Lease. If the Sublet Space is damaged or destroyed and
Landlord or Sublessor exercises any option either may have to terminate the Master Lease, this
Sublease shall automatically terminate as of the date of the termination of the Master Lease,
unless Landlord and Sublessee have theretofore entered into a recognition and attornment agreement
whereby Landlord has agreed to accept this Sublease as a direct lease between Landlord and
Sublessee. Sublessee shall have no independent right to terminate this Sublease upon damage or
destruction.

11.

 

          b. Continuation of Sublease. If the Master Lease is not terminated following any
damage or destruction as provided in Section 10.a above, this Sublease shall remain in full force
and effect.

          c. Proceeds; Rent Abatement. Despite anything contained in the Master Lease to the
contrary, as between Sublessor and Sublessee only, in the event of damage to or Condemnation of the
Sublet Space, all insurance proceeds or Condemnation awards received by Sublessor under the Master
Lease shall be deemed to be the property of Sublessor, and Sublessor shall have no obligation to
rebuild or restore the Sublet Space. In the event of any casualty or Condemnation affecting the
Sublet Space which results in an abatement of rent under the Master Lease, Basic Rent shall be
abated under this Sublease only as to the affected portion of the Sublet Space, and then only to
the extent that rent is abated under the Master Lease.

     11. Eminent Domain. The following provisions shall apply with respect to any
condemnation of the Sublet Space:

          a. Total Condemnation. If all of the Premises is condemned by eminent domain,
inversely condemned or sold in lieu of condemnation, for any public or a quasi-public use or
purpose (“Condemned” or “Condemnation”), this Sublease shall terminate as of the date of title
vesting in such proceeding, and Basic Rent shall be adjusted to the date of termination.

          b. Partial Condemnation. If any portion of the Premises is Condemned, and Sublessor
exercises any option to terminate the Master Lease, this Sublease shall automatically terminate as
of the date of the termination of the Master Lease, unless Landlord and Sublessee have theretofore
entered into a recognition and attornment agreement whereby Landlord has agreed to accept this
Sublease as a direct lease between Landlord and Sublessee. If the Master Lease is not terminated
following any such Condemnation, this Sublease shall remain in full force and effect. Sublessee
shall have no independent right to terminate this Sublease upon any Condemnation. Sublessee hereby
waives the provisions of California Code of Civil Procedure Section 1265.130 permitting a court of
law to terminate this Sublease.

          c. Sublessee’s Award. Subject to the provisions of the Master Lease, Sublessee shall
have the right to recover from the condemning authority, but not from Sublessor, such compensation
as may be separately awarded to Sublessee in connection with costs and removing Sublessee’s
merchandise, furniture, fixtures, leasehold improvements and equipment to a new location.

     12. Assignment and Subletting. The following provisions shall apply with respect to
any assignment and/or subletting of the Sublet Space by Sublessee:

          a. Consent Required. Sublessee shall not directly or indirectly (including, without
limitation, by merger, consolidation, reorganization, acquisition or other transfer of any interest
in Sublessee or by transfer to any parent, subsidiary or affiliate of Sublessee), voluntarily or by
operation of law, sell, assign, encumber, mortgage, pledge or otherwise transfer or hypothecate all
or any part of its interest in or rights with respect to this

12.

 

Sublease or the Sublet Space (collectively, “Assignment”), or permit all or any portion of the
Sublet Space to be occupied by anyone other than itself or sublet all or any portion of the Sublet
Space (including, without limitation, any sublease to, or occupancy by, any parent, subsidiary or
affiliate of Sublessee) (collectively, “Sublease”), without obtaining Sublessor’s prior written
consent in each instance, which consent shall not be unreasonably withheld or delayed. In
determining whether or not to consent to a proposed Assignment or Sublease, Sublessor may consider
the following factors, among others, all of which are deemed reasonable: (i) whether the proposed
assignee or subtenant has sufficient financial capability to perform its obligations under this
Sublease; (ii) whether the proposed use of the Sublet Space by the proposed assignee or subtenant
is consistent with the Permitted Uses set forth in the Defined Terms section of this Sublease; and
(iii) whether Landlord has consented in writing to the proposed Assignment or Sublease (it being
understood that a condition to Sublessor’s consent to any Assignment or Sublease is Landlord’s
written consent to the same). Any Assignment or Sublease that is not in compliance with this
Section 12 shall be null and void and, at the option of Sublessor, shall constitute a noncurable
default by Sublessee under this Sublease, and Sublessor shall be entitled to pursue any right or
remedy available to Sublessor under this Sublease or under the laws of the State of California. No
Assignment or Sublease shall release or relieve Sublessee of its obligations under this Sublease.
The acceptance of Rent by Sublessor from any other person shall not be deemed to be a waiver by
Sublessor of any provision of this Sublease or to be a consent to any Assignment or Sublease.
Consent to one (1) Assignment or Sublease shall not be deemed to constitute consent to any
subsequent attempted Assignment or Sublease.

          b. Assignment Documentation. With respect to any Assignment, any assignee approved by
Sublessor pursuant to this Section 12 shall, from and after the effective date of the Assignment,
assume all obligations of Sublessee under this Sublease and shall be and remain liable jointly and
severally with Sublessee for the payment of Rent, and for the performance of all of the terms,
covenants, conditions and agreements herein contained on Sublessee’s part to be performed. No
Assignment shall be binding on Sublessor unless Sublessee shall deliver to Sublessor a counterpart
of the Assignment and an instrument that contains a covenant of assumption by such assignee
satisfactory in form and substance to Sublessor, and consistent with the requirements of this
Section 12.b. Any failure or refusal of such assignee to execute such instrument of assumption
shall constitute a default under this Sublease but shall not release or discharge such assignee
from its liability as set forth above.

          c. Transfer Consideration. If Sublessor consents to an Assignment or Sublease, as a
condition thereto which the Parties hereby agree is reasonable, Sublessee shall pay to Sublessor
fifty percent (50%) of any rent, additional rent or other consideration payable by the assignee or
subtenant in connection with the Assignment or Sublease in excess of the Basic Rent and Additional
Rent payable by Sublessee under this Sublease on a per rentable square foot basis if less than all
of the Sublet Space is transferred, in either case without any deduction therefrom.

          d. Recapture Right. The recapture right set forth in Section 23.4 of the Master Lease
has been incorporated by reference into this Sublease pursuant to Section 3 above and may be
exercised by Sublessor with respect to any Assignment or Sublease (as defined in Section 12.a
above) satisfying the requirements of such Section 23.4.

13.

 

     13. Insurance. All insurance policies required to be carried by Sublessee pursuant to
the Master Lease shall contain a provision whereby Sublessor and Landlord are each named as
additional insureds under such policies.

     14. Maintenance and Repair.

          a. Obligations. Sublessee shall, at its sole cost and expense, maintain the Sublet
Space in good order, condition and repair during the Sublease Term, ordinary wear and tear
excepted, including light bulbs and equipment within the Sublet Space, fixtures, interior walls and
interior surfaces of exterior walls and Alterations made by or for the benefit of Sublessee. All
such work shall be done with contractors previously approved in writing by Sublessor. Sublessee
shall inform Sublessor in writing of any material repair or maintenance projects prior to their
commencement. Sublessor shall maintain the plumbing systems, electrical and lighting fixtures,
HVAC systems, ceilings, windows, doors, plate glass and skylights located within the Building in
good condition and repair, ordinary wear and tear excepted, and Sublessee’s pro rata share (as
reasonably determined by Sublessor) of the costs thereof shall be due and payable as additional
rent to Sublessor within thirty (30) days after Sublessor’s demand therefor. Notwithstanding the
foregoing, Sublessee acknowledges that Landlord has the right, pursuant to Section 12.2 of the
Master Lease, to take over the maintenance and repair of any HVAC, plumbing, electrical or other
systems or equipment within the Premises and to include the cost of such work as Operating Expenses
of the Building.

          b. Failure to Perform. If Sublessee fails to perform Sublessee’s obligations under
this Section 14, Sublessor may, in addition to any other rights and remedies available under this
Sublease, at law or in equity, enter upon the Sublet Space after five (5) days’ notice to Sublessee
(except in the case of emergency, in which case no notice shall be required), perform such
obligations on Sublessee’s behalf and put the Sublet Space in good order, condition and repair, and
the cost thereof, together with interest thereon at the Effective Rate, shall be due and payable as
additional rent to Sublessor upon demand by Sublessor. Sublessor’s performance of Sublessee’s
obligations under this Section 14.b shall not be deemed a waiver or cure of such default by
Sublessee.

          c. Repairs Upon Surrender. Upon the expiration or earlier termination of the Sublease
Term, Sublessee, at its sole cost and expense, shall surrender the Sublet Space to Sublessor in the
condition described in, and in accordance with the terms of, Section 29 of the Master Lease. Any
damage or deterioration of the Sublet Space shall not be deemed ordinary wear and tear if the same
could have been prevented by reasonable maintenance practices. Sublessee shall repair any damage
to the Sublet Space occasioned by the installation or removal of Sublessee’s Alterations, trade
fixtures, furnishings and/or equipment.

     15. Payment Upon Execution. Upon execution of this Sublease, and as a condition
precedent to the effectiveness of this Sublease, Sublessee shall pay to Sublessor cash in the
amount of Three Hundred Thirty Five Thousand Four Hundred Sixty and 75/100 Dollars ($335,460.75)
(the “Payment”). The Payment shall be non-refundable to Sublessee, except and then only to the
extent as expressly set forth in the last sentence of this Section 15 and in Section 19.c below.
Sublessor may use and commingle the Payment with other funds of Sublessor. Provided that, as of
the first day of the month of the Sublease Term for which the applicable

14.

 

credit to Basic Rent contemplated in this sentence is to be made, this Sublease is in full
force and effect and Sublessee is not in default of any of its obligations under this Sublease,
Sublessor shall credit the Payment to Basic Rent payable by Sublessee under this Sublease for the
original Sublet Space as follows (i) an amount equal to Twenty Four Thousand Three Hundred Eight
and 75/100 Dollars ($24,308.75) shall be credited to Basic Rent for the original Sublet Space for
each of the following months: January 2006, February 2006 and March 2006; and (ii) an amount equal
to Twenty Nine Thousand One Hundred Seventy and 50/100 Dollars ($29,170.50) shall be credited to
Basic Rent for the original Sublet Space for each of the following months: April 2010, May 2010,
June 2010, July 2010, August 2010, September 2010, October 2010, November 2010 and December 2010.
In the event of any termination of this Sublease caused solely by the fault or default of Sublessor
(including any termination of this Sublease due to a termination of the Master Lease caused solely
by the fault or default of Sublessor), Sublessee shall be entitled to the return (without payment
of any interest thereon) of any portion of the Payment which was to have been credited by Sublessor
pursuant to this Section 15 to Basic Rent payable by Sublessee under this Sublease for the original
Sublet Space becoming due after the effective date of such termination of this Sublease.

     16. Right of First Offer. Subject to, and in accordance with, the provisions of this
Section 16, effective as of the Commencement Date and continuing thereafter throughout the Sublease
Term, Sublessee shall have a right of first offer (the “Right of First Offer”) to sublease any
portion of the Premises, other than the Expansion Space, which is separately addressed in
Section 17 below and shall be subleased by Sublessee, if at all, pursuant to Section 17 below (the
“First Offer Space”) when the First Offer Space becomes “available for sublease” during the
Sublease Term. Space shall not be deemed “available for sublease” if (i) the subtenant under an
expiring sublease of such space renews or extends its sublease pursuant to a right or option in
effect as of the Commencement Date, or (ii) Landlord exercises any recapture right under the Master
Lease with respect to such space or otherwise subleases or takes such space back from Sublessor.
Upon First Offer Space becoming available for sublease, Sublessor shall deliver to Sublessee a
written notice setting forth the terms and conditions upon which Sublessor would be willing to
sublease the First Offer Space to Sublessee (the “Notice”), which terms and conditions shall be
based on Sublessor’s reasonable determination of the fair market rental value of the First Offer
Space, whereupon Sublessee shall have ten (10) business days in which to elect by delivery of
written notice to Sublessor whether to sublease the First Offer Space on all of the terms and
conditions of the Notice. If Sublessee does not exercise its Right of First Offer with regard to
the Notice within the ten (10) business day period, Sublessor may sublease the First Offer Space to
any party upon any terms and conditions Sublessor elects, and the Right of First Offer shall
terminate and have no further force or effect during the Sublease Term with respect to the
particular First Offer Space that was the subject of the Notice. In other words, if Sublessee does
not timely exercise its Right of First Offer with respect to a particular First Offer Space,
Sublessee shall thereafter have no further rights under this Section 16 with respect to that
particular First Offer Space, and Sublessor shall have no obligation to offer that particular First
Offer Space to Sublessee again. If Sublessee timely exercises its Right of First Offer with regard
to the Notice, the Parties shall promptly enter into an amendment to this Sublease confirming
Sublessee’s sublease of the First Offer Space on the terms set forth in the Notice and for a term
coterminous with the original Sublet Space (including appropriate revisions to Basic Rent,
description of the Sublet Space, Sublessee’s Share and the number of parking spaces available to
Sublessee pursuant to this Sublease), which amendment shall be

15.

 

subject
to the consent of Landlord. The Right of First Offer is personal to Sublessee and shall be inapplicable and
null and void if, on the date of exercise of the Right of First Offer or on the date immediately
preceding the date the sublease term for the First Offer Space is to commence (i) Sublessee has
assigned its interest under this Sublease, or (ii) Sublessee is not in occupancy of the entire
original Sublet Space and the entirety of any First Offer Space and Expansion Space, as defined in
Section 17 below, previously subleased by Sublessee pursuant to this Sublease (or, if possession of
any such previously-subleased First Offer Space and/or Expansion Space has not yet been delivered
to Sublessee, Sublessee does not intend to occupy the entirety of such space once possession is
delivered, but instead intends to assign its interest under this Sublease with respect to such
space or sublease such space in whole or in part). Additionally, the Right of First Offer shall be
inapplicable and null and void if Sublessee is in default under this Sublease on the date of
Sublessee’s exercise of the Right of First Offer or on the date immediately preceding the date the
sublease term for the First Offer Space is to commence.

     17. Option to Expand. As of the Effective Date, Sublessor subleases that certain
portion of the Premises consisting of approximately nineteen thousand (19,000) rentable square feet
located on the first floor of Buildings F and G (the “Expansion Space”) to Mailfrontier, Inc.
(“Mailfrontier”). The term of Mailfrontier’s sublease (the “Mailfrontier Sublease”) expires on
November 30, 2006, and Mailfrontier has two (2) options to extend the term of the Mailfrontier
Sublease, each for a period of one (1) year. Subject to, and in accordance with, the provisions of
this Section 17, upon the expiration of the initial term of the Mailfrontier Sublease, provided
Mailfrontier has not exercised its option to extend the initial term of the Mailfrontier Sublease,
or, upon the expiration of the extended term of the Mailfrontier Sublease, in the event
Mailfrontier has exercised one (1) or both of its one (1)-year options to extend the term of the
Mailfrontier Sublease, Sublessee shall have the option (the “Expansion Option”) to expand into the
Expansion Space. Sublessee shall exercise the Expansion Option by delivering a notice (the
“Expansion Space Notice”) to Sublessor within ten (10) business days after Sublessee’s receipt of
written notice from Sublessor confirming the expiration date of the term of the Mailfrontier
Sublease (based on Mailfrontier’s exercise, or failure to exercise, its extension options under the
Mailfrontier Sublease). If Sublessee does not timely deliver the Expansion Space Notice, Sublessor
may sublease the Expansion Space to any party upon any terms and conditions Sublessor elects, and
the Expansion Option shall terminate and have no further force or effect. If Sublessee timely
delivers the Expansion Space Notice, the Expansion Space shall be subleased by Sublessee upon the
same terms and conditions applicable to the original Sublet Space and for a term coterminous with
the original Sublet Space, except that the Basic Rent for the Expansion Space shall be equal to the
then-Prevailing Market Rent for the Expansion Space, as determined pursuant to Exhibit D,
attached hereto. Promptly after the determination of the Prevailing Market Rent for the Expansion
Space, the Parties shall enter into an amendment to this Sublease confirming Sublessee’s sublease
of the Expansion Space (including appropriate revisions to Basic Rent, description of the Sublet
Space, Sublessee’s Share and the number of parking spaces available to Sublessee pursuant to this
Sublease), which amendment shall be subject to the consent of Landlord. The Expansion Option is
personal to Sublessee and shall be inapplicable and null and void if, on the date of the Expansion
Space Notice or on the date immediately preceding the date the sublease term for the Expansion
Space is to commence, (i) Sublessee has assigned its interest under this Sublease, or (ii)
Sublessee is not in occupancy of the entire original Sublet Space and the entirety of any First
Offer Space, as defined in Section 16 above, previously subleased by Sublessee pursuant to this
Sublease (or, if

16.

 

possession of any such previously-subleased First Offer Space has not yet been delivered to
Sublessee, Sublessee does not intend to occupy the entirety of such First Offer Space once
possession is delivered, but instead intends to assign its interest under this Sublease with
respect to such First Offer Space or sublease such First Offer Space in whole or in part).
Additionally, the Expansion Option shall be inapplicable and null and void if Sublessee is in
default under this Sublease on the date of the Expansion Space Notice or on the date immediately
preceding the date the sublease term for the Expansion Space is to commence.

     18. Brokerage Commission. Sublessor shall pay a brokerage commission to the Broker
for Sublessee’s subletting of the Sublet Space as provided for in a separate agreement between
Sublessor and the Broker. Sublessee warrants for the benefit of Sublessor that its sole contact
with Sublessor or the Sublet Space in connection with this transaction has been directly with
Sublessor and the Broker. Sublessee further warrants for the benefit of Sublessor that no other
broker or finder can properly claim a right to a commission or a finder’s fee based upon contacts
between the claimant and Sublessee with respect to the other party or the Sublet Space. Sublessee
shall indemnify, defend by counsel acceptable to Sublessor and hold Sublessor harmless from and
against any loss, cost or expense, including, but not limited to, attorneys’ fees and court costs,
resulting from any claim for a fee or commission by any broker or finder, other than any claims by
the Broker, in connection with the Sublet Space and this Sublease.

     19. Miscellaneous.

          a. Entire Agreement. This Sublease contains all of the covenants, conditions and
agreements between the Parties concerning the Sublet Space, and shall supersede all prior
correspondence, agreements and understandings concerning the Sublet Space, both oral and written.
No addition or modification of any term or provision of this Sublease shall be effective unless set
forth in writing and signed by both Sublessor and Sublessee.

          b. Captions. All captions and headings in this Sublease are for the purposes of
reference and convenience and shall not limit or expand the provisions of this Sublease.

          c. Landlord’s Consent. This Sublease is conditioned upon Landlord’s written approval
of this Sublease within thirty (30) days after the Effective Date. If Landlord refuses to consent
to this Sublease, or if the thirty (30) day consent period expires, this Sublease shall terminate
and neither Party shall have any continuing obligation to the other with respect to the Sublet
Space; provided Sublessor shall return the Letter of Credit and the Payment (without payment of any
interest thereon), if previously delivered to Sublessor, to Sublessee.

          d. Authority. Each person executing this Sublease on behalf of a party hereto
represents and warrants that he or she is authorized and empowered to do so and to thereby bind the
Party on whose behalf he or she is signing.

          e. Notices. All notices, demands, consents and approvals which may or are required to
be given by either Party to the other hereunder shall be in writing and either personally
delivered, sent by commercial overnight courier, or mailed, certified or registered, postage
prepaid, and addressed to the Party to be notified at the address for such Party as

17.

 

specified in the Defined Terms section of this Sublease or to such other place as the Party to
be notified may from time to time designate by at least ten (10) days’ notice to the notifying
Party. Notices shall be deemed served upon receipt or refusal to accept delivery. Sublessee
appoints as its agent to receive the service of all default notices and notice of commencement of
unlawful detainer proceedings the person in charge of or apparently in charge of occupying the
Sublet Space at the time, and, if there is no such person, then such service may be made by
attaching the same on the main entrance of the Sublet Space.

          f. Parking. During the Term of this Sublease, Sublessee may use fifty nine (59) of
the parking spaces available for the Development (subject to adjustment pursuant to the terms of
Section 2.2 of the Master Lease), on an unreserved, non-exclusive, and unassigned basis, without
additional charge to Sublessee. Sublessee shall use such parking spaces pursuant to all of the
terms and conditions of the Master Lease with respect thereto. In the event any First Offer Space
or the Expansion Space is added to this Sublease pursuant to Section 16 or Section 17 above,
respectively, Sublessee shall have the right to use, in addition to and on the same terms and
conditions of this Section 19.f applicable to, the original fifty nine (59) parking spaces, three
(3) parking spaces available for the Development for each one thousand (1,000) rentable square feet
of the First Offer Space or Expansion Space, as applicable.

          g. Common Areas. Sublessor has the right, in its sole discretion, from time to time,
to: (i) make changes to the common areas located in the Building, including, without limitation,
changes in the location, size, shape and number of entrances, corridors and walkways; (ii) close
such common areas temporarily for maintenance purposes so long as reasonable access to the Sublet
Space remains available; (iii) use such common areas while engaged in making additional
improvements, repairs or alterations to the Building or any portion thereof; and (iv) do and
perform any other acts or make any other changes in, to or with respect to such common areas and
other parts of the Building as Sublessor shall deem appropriate, including but not limited to,
allowing the first floor lobby area to be used by subtenants of the Building. The exercise of
Sublessor’s rights pursuant to this subsection shall be subject to the condition that such exercise
does not materially interfere with Sublessee’s use of the Sublet Space.

          h. Signage. Sublessor shall, at Sublessor’s sole cost and expense, install standard
lobby directory signage in the Building designating the Sublet Space as Sublessee’s space. In
addition, Sublessee, at Sublessee’s sole cost and expense, shall have the right to install
identification signage upon the entry to the Sublet Space, provided such signage shall be installed
in accordance with, and shall otherwise subject to the terms of, the Master Lease, and shall
require the prior written consent of both Landlord and Sublessor as to the materials and content of
such sign (and as to any subsequent changes to such sign). Sublessee, at Sublessee’s sole expense,
shall: (i) maintain such sign during the Sublease Term, and (ii) remove such sign upon the
expiration or earlier termination of this Sublease and return the area on which the sign is located
to the condition in which it existed prior to the installation of such sign.

          i. First Amendment. Pursuant to that certain Sublease dated as of May 6, 2004 between
Sublessor, as sublandlord, and Sublessee, as subtenant, with respect to the

18.

 

premises located at 3160 Porter Drive in Palo Alto, California, effective as of July 1, 2004,
Sublessee has agreed to perform and observe all of the obligations, covenants, terms and
conditions to be performed or observed by Sublessor under the First Amendment arising from and
after July 1, 2004, and Sublessee hereby reaffirms its agreement to so perform and observe such
obligations, covenants, terms and conditions. The First Amendment relates to the walkway that
connects the Building to the building located at 3160 Porter Drive.

[Remainder of this page is left intentionally blank]

19.

 

     IN WITNESS WHEREOF, the Parties hereto have executed one (1) or more copies of this Sublease,
effective as of the Effective Date.

	 	 	 	 	 
	 	“Sublessor”

INCYTE CORPORATION, a Delaware corporation

 	 
	 	By:  	/s/ David C. Hastings
 	 
	 	 	 	 
	 	Its:	EVP, CFO
 	 	 
	 
	 	 	 
	 	By:  	 	 
	 	 	 	 
	 	Its:	 	 	 
	 

	 	 	 	 	 
	 	“Sublessee”

CONNETICS CORPORATION, a Delaware corporation

 	 
	 	By:  	/s/ John L. Higgins
 	 
	 	 	 	 
	 	Its:	CFO
 	 	 
	 
	 	 	 
	 	By:  	 	 
	 	 	 	 
	 	Its:	 	 	 
	 

20.

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00084-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00084-of-00352.parquet"}]]