Document:

Exhibit 10.6

 

AGREEMENT

 

This Agreement is entered into as of on December
5, 2022, effective as of March 31, 2022 (the “Commencement Date”), by and between Regentis Biomaterials Ltd.,
a company incorporated in the State of Israel whose address is 60 Medinat Hayehudim Street, Entrance C. Herzeliya, Israel (the “Company”),
and Mr. Noam Band, ID no. [_________], of [______________]., Tel Aviv, Israel (the “Service Provider”).

 

	(A)	The Company desires to engage the Service Provider to serve
as the Company’s Chief Operating (COO), all in accordance with the terms of this Agreement (the “Services”)
as of the Commencement Date;

 

	(B)	The parties agree, as per the Service Provider’s specific wish
and requirement, made as a result of considerations and benefits personal to the Service Provider, that the Services shall be provided
to the Company by the Service Provider on an independent contractor basis, absent an employment relationship between the Company and
the Service Provider;

 

	(C)	The Service Provider is aware of all the financial consequences
resulting from the engagement of the Service Provider as an independent contractor, and is also aware that the Service Provider shall
receive from the Company consideration that would greatly exceed the Service Provider’s salary, had the Service Provider been hired as
an employee of the Company;

 

	(D)	This Agreement is entered into in reliance upon, inter alia,
the declarations of the Service Provider that the Services are provided solely on an independent contractor basis and that no claim shall
be submitted by the Service Provider or anyone on his behalf contradicting such declaration.

 

NOW THEREFORE, in consideration of the
mutual promises, covenants and understandings contained herein, the parties agree as follows:

 

	1.	Representations, Duties and Obligations of Service Provider

 

		1.1.	The Service Provider declares and undertakes that he is free
to provide the Company with the Services, upon the terms contained in this Agreement, and there are no restrictions preventing the Service
Provider from fully performing all duties hereunder, including but not limited to non-compete or other obligations that the Service Provider
is bound by.

 

		1.2.	The Service Provider shall provide the Services to the Company,
in a scope as shall be agreed between the Service Provider and the Chief Executive Officer of the Company (the “CEO”,
or the chairman of the Board, as the case may be), but shall not exceed that of a full time employee, at any location designated by the
Company.

 

		1.3.	The Service Provider shall provide the Services in accordance
with the directions of the Company’s CEO (or the chairman of the Board, as the case may be), and will report directly to the CEO.
The Service Provider shall not have any other person or entity perform any of the Services.

 

		1.4.	The Service Provider undertakes to perform all duties and
obligations under this Agreement with the highest degree of professionalism and to the full satisfaction of the Company and will ensure
the use of all professional knowledge, experience and skills in providing the Services, which shall be performed in a loyal, devoted
and professional manner in accordance with the terms of this Agreement.

 

     

     

    

 

		1.5.	The Company acknowledges that at the time of the Commencement
Date, the Service Provider provides services to other companies, provided that the services so provided is not a competitor of the Company.

 

		1.6.	The Service Provider will notify the Company immediately
if anything occurs or comes to his attention which would or might prevent him from providing the Services at the level required by the
Company.

 

		1.7.	The Service Provider shall not, directly or indirectly, accept
any commission, rebate, discount or gratuity in cash or in kind, from any person who has or is likely to have a business relationship
with the Company related in any way to the Service provided by the Service Provider.

 

	2.	Consideration

 

		2.1.	In consideration for the provision by Service Provider of
the Services, and subject to the fulfillment of the Service Provider’s obligations under this Agreement, from such time as the Company
shall complete an initial public offering of the Company’ shares and raise funds in such offering (the “IPO”),
the Service Provider shall be entitled to a payment of a monthly fee of US$6,000 (the “Fee”) plus VAT.

 

		2.2.	The Payment for each month’s Fee shall be made no later
than the ninth (9th) day of the following calendar month against a valid tax invoice issued by the Service Provider to the Company in
respect of the Fee for the Services provided in the previous month.

 

		2.3.	Other than the payment of the Fee and the reimbursement of
expenses, as further detailed below, the Service Provider shall not be entitled to any further compensation in connection with the discharge
of its responsibilities hereunder.

 

		2.4.	The Company shall reimburse the Service Provider for Service
Provider’s reasonable out of pocket expenses incurred during its performance of the Services, provided said expenses have been
approved by the Company in advance and in writing, all subject to any Company policies as may be in force from time to time and against
the provision of proper receipts.

 

		2.5.	In addition, and subject
to the approval of the Board of Directors, the Service Provider may be granted with options to acquire ordinary shares of the Company
and an Employee Stock Option Plan (the “Plan”) and Section 102 (“Section
102”) of the Income Tax Ordinance (the “Options”).
The number of Options to be granted to the Service Provider shall be equal to 0.40% of the issued and outstanding share capital of the
Company as of the date hereof, and such Options shall vest monthly over a period of three (3) years from the date of their grant. The
exercise price of such Options shall be equal to the nominal value of the ordinary shares of the Company. The Options shall further be
subject to the terms and conditions of the Company’s Plan and Section 102.

 

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		2.6.	The Service Provider hereby represents and acknowledges that
all amounts paid under this Agreement in consideration for the provision of the Services are higher than the consideration that would
have been paid by the Company to an employee of the Company for the provision of the same or substantially the same services.

 

		2.7.	All payments under this Agreement include all taxes, duties,
levies, deductions or similar governmental charges (hereinafter referred to as “Taxes”). The Service Provider shall
pay all Taxes associated with the Services. The Company will pay any required withholding tax within its territory and provide the Service
Provider a certificate for such amount.

 

		2.8.	As Noam Band is an officer of the Company, he shall be added
to the Company’s directors and officers insurance policy.

 

	3.	Status of Parties

 

		3.1.	The relationship between the Service Provider and the Company,
in compliance with the Service Provider’s request, is one of principal and independent contractor. The Service Provider must perform
and continue to perform all actions legally required to establish and maintain his status as an independent contractor with an independent
business. The parties expressly declare that no employment relationship exists between the Company and the Service Provider.

 

		3.2.	If, notwithstanding anything contained in this Agreement
any person shall claim, or a judicial authority shall determine, that the Service Provider provided the Services under this Agreement
as an employee of the Company, then the following provisions shall apply:

 

		3.2.1. 	For the period as to which it is claimed or determined that
an employment relationship existed between the Company and the Service Provider (the “Relevant Period”), the Service
Provider shall not be entitled to the Fee, but only 60% thereof (the “Reduced Fee”).

 

		3.2.2. 	The Reduced Fee shall constitute the full Fee payable to the
Service Provider as salary in connection with said employment relationship, on which basis any social benefits will be calculated - to
the extent that such social benefits are required to be paid to or in respect of the Service Provider pursuant to any third party authority’s
decision reclassifying the Service Provider as an employee.

 

		3.2.3.	In view thereof, an accounting shall be conducted between
the parties, and the Service Provider shall immediately return and pay to the Company all amounts paid to him in excess of the Reduced
Fee for the Relevant Period, along with linkage differentials and interest from the date of payment of each amount by the Company to
the Service Provider and up to the date upon which actual return and payment of the funds is made by the Service Provider, all based
on the Consumer Price Indices known at the relevant dates and as provided by the Adjudication of Interest and Linkage Law, 1961.

 

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		3.3.	In addition, in the event that the relationship between the
Company and the Service Provider shall be claimed, regarded or determined by any third party, including any governmental or judicial
or tax authority to be an employment relationship, the Service Provider shall reimburse and indemnify the Company for any expense and
payment incurred by or demanded of the Company as a consequence, no later than seven days of its receipt of such demand.

 

		3.4.	The Company shall be entitled to offset any amounts due to
it under this Section ‎‎‎3 from any amounts payable to the Service Provider under this Agreement.

 

	4.	Term and Termination

 

		4.1.	The term of this Agreement shall begin on the Commencement
Date and shall continue unless terminated in accordance with the terms of this Agreement (the “Term”). Either party
may terminate this Agreement immediately without cause upon prior written notice of 60 days to the other party.

 

		4.2.	Notwithstanding Section ‎4.1 above, the Company may terminate
this Agreement forthwith and without prior notice (Termination for Cause) if: (i) the Service Provider commits a fundamental breach of
the Agreement or other duties owed to the Company, including but not limited to any breach of the Service Provider’s representations
or obligations under Sections ‎1, ‎3, ‎5, ‎6 or ‎7 of this Agreement; (ii) in the event of any act or omission of
the Service Provider which would have entitled the Company legally to dismiss the Service Provider without severance pay, in whole or
in part, had the Service Provider been engaged as an employee of the Company; (iii) if the Service Provider engages or engaged in any
act of dishonesty or fraud, whether or not it involves the Company. The foregoing is without prejudice to any relief available to the
Company by law or under this Agreement.

 

		4.3.	Upon termination of this Agreement, or at such other time
as directed by the Company, the Service Provider shall immediately return to the Company all assets and Confidential Information (as
defined below) and any and all copies thereof, in the Service Provider’s possession or control which belong to, or have been entrusted
to it by, the Company. The Service Provider shall not retain or make copies thereof in whatever form and shall neither have, nor retain,
any proprietary interest in such assets.

 

	5.	Proprietary Rights

 

		5.1.	For the purposes of this Agreement “Intellectual Property”
means all intellectual property rights relating to the business of the Company, in connection with the field of tissue
repair solutions that restore the health and quality of life of patients (the “Field”), whether or not patentable,
including without limitation (i) patents and patent applications, and any divisional, continuation, continuation in part, reissue, renewal
or re-examination patent issuing therefrom (including any foreign counterparts), (ii) copyrights and registrations thereof, (iii) trade
secrets and other confidential business information, whether patentable or unpatentable and whether or not reduced to practice, know-how,
financial, marketing and business data, pricing and cost information, business and marketing plans and customer and supplier lists and
information, inventions and, with respect to all of the foregoing, related confidential documentation, (iv) trademarks, service marks,
trade names and applications and registrations therefor, and (v) other proprietary rights relating to the foregoing, and any rights analogous
to the foregoing anywhere in the world.

 

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		5.2.	The Service Provider and the Company agree that the Company
shall be the owner, upon creation, of all right, title and interest in, to and under the Intellectual Property created in or as a result
of any communication between the Service Provider and the Company prior to and leading to this agreement, in particular as a result of
any information divulged by the Company to the Service Provider (“Prior Inventions”). The Service Provider and the Company
further agree that the Company is and shall be the owner, upon creation, of all right, title and interest in, to and under the Intellectual
Property created in the course of, or in consequence of, the performance of the Agreement, which shall be deemed work made for hire,
owned exclusively by the Company, and any ensuing rights, including all rights, powers, privileges and immunities arising thereunder
or conferred thereby, and all applications for intellectual or industrial property that may hereinafter be filed for the Intellectual
Property in any jurisdiction, and all divisions, renewals and continuations thereof, and all registrations that may be granted thereon
and all extensions and reissues thereof, together with any and all rights of priority relating to the Intellectual Property and any registrations
that may be granted thereon, expressly including the right to sue for past infringement (all the above together with the Prior Inventions,
as defined below, referred to as the “Company’s IP Rights”).

 

		5.3.	If the ownership in any of the Company’s IP Rights,
as a matter of law, not vest in the Company upon creation, then the Service Provider shall assign and does hereby irrevocably assign
to the Company, its successors, legal representatives all right, title and interest in, to and under the Company’s IP Rights to
the extent that the Service Provider may have such rights, and the Service Provider shall have no right whatsoever in, to and under the
Company’s IP Rights. To the extent that any right in the Company’s IP Rights may not under applicable law be assigned to
the Company as above, the Service Provider hereby waives any and all such rights in favor of the Company, and the Service Provider shall
not have any claim to any right, moral rights, compensation, royalties or reward in respect of any such Company’s IP Rights, including,
but not limited to, the payment of any consideration pursuant to Section 134 of the Israeli Patent Law, 1967.

 

		5.4.	The Service Provider agrees and undertakes to: (i) promptly
disclose to the Company in writing, sufficient to identify the Company’s IP Rights in question, the creation or existence of all
such Company’s IP Rights; and, (ii) take such action, during the term of the Agreement and thereafter, as the Company may request,
to enable the Company to acquire, evidence, transfer, maintain, vest, enforce or confirm the Company’s right, title and interest
in and to the Company’s IP Rights.

 

		5.5.	The Service Provider hereby irrevocably appoints the Company
and its duly authorized officers and agents to be the Service Provider’s agents and attorney in fact to act for and on the behalf of
the Service Provider and in its stead and to do any action and make any legal disposition in respect of the Company’s IP Rights,
including without limitation, to execute and file any documents, and generally do everything possible to ensure that the Company, its
successors, legal representatives and assigns, obtain and enforce proper protection for the Company’s IP Rights in all jurisdictions,
all the foregoing with the same legal force and effect as if executed by the Service Provider.

 

		5.6.	The Service Provider further covenants and agrees that he
will communicate to the Company, its successors, legal representatives and assigns, any facts known to him representing the Company’s
IP Rights, testify in any legal proceeding, sign all lawful papers, execute all divisional, continuing, reissue and foreign applications,
make all rightful oaths, and generally do everything possible to aid the Company, its successors, legal representatives and assigns,
to obtain and enforce proper protection for the Company’s IP Rights.

 

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	6.	Confidentiality

 

		6.1.	The Service Provider agrees that all the Company information,
whether in oral form, visual form or in writing, including but not limited to, all specifications, formulas, prototypes, computer programs
and any and all records, data, ideas, methods, techniques, processes and projections, plans, marketing information, business plans, projects,
pricing, customers and customer information, materials, financial statements, memoranda, analyses, notes, legal documents, and other
data and information, as well as test results, processes, know-how, improvements, inventions, techniques, patents (whether pending or
duly registered) and any know-how related thereto, relating to the Company and its affiliates, the Company IP Rights, and the terms and
conditions of this Agreement, will be considered and referred to collectively as “Confidential Information”.

 

		6.2.	The Service Provider agrees that it shall not use Confidential
Information for its own, or any third party’s benefit; the Service Provider further agrees to accept and use Confidential Information
solely for the purpose of providing the Services for the benefit of the Company; the Service Provider shall keep in confidence and trust
all Confidential Information and shall not, directly or indirectly, disclose, publish, or disseminate Confidential Information to any
third party or allow the same to occur.

 

	7.	Non-Competition and Non-Solicitation

 

During the term of this Agreement and for a period
of twelve (12) months following its termination, the Service Provider shall not:

 

		7.1.	directly or indirectly, in any capacity whatsoever, whether
independently or as a shareholder, an employee, Service Provider, an officer or any managerial capacity, carry on, set up, own, manage,
control or operate, be employed, engaged or interested in a business, anywhere in the world, which competes with, or proposes to compete
with the Company or any of its affiliates (the “Group”), in connection with slow release of analgesic agent.

 

		7.2.	directly or indirectly, in any way (i) offer, solicit or
attempt to solicit, induce or attempt to induce or endeavor to entice away, any person with whom any member of the Group has or had or
shall have any contractual or commercial relationship as a Service Provider, licensor, joint venturer, supplier, customer, distributor,
agent or contractor of whatsoever nature, existing or under negotiation on or prior to date of termination of this Agreement, to cease
his, her or its relationship with that member of the Group, or otherwise interfere in any way with the relationship between that member
of the Group and such person or (ii) have any business dealings with any such person.

 

		7.3.	directly or indirectly, in any way offer, solicit or attempt
to solicit for employment or other engagement, or otherwise contract or seek to contract the services of, any individual who is, at the
effective date of termination of this Agreement, employed or engaged (whether directly or indirectly) by any member of the Group or induce
or entice or attempt to induce or entice such individual to leave such employment or other engagement or otherwise interfere in his or
her relationship with any member of the Group.

 

The Service Provider acknowledges that its obligations
under this Section are reasonable, in light of knowledge it will gain of the Group’s Confidential Information and that the consideration
it receives hereunder is paid, inter alia, as consideration for its undertaking under this Section ‎7.

 

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	8.	No Conflicting Obligations

 

		8.1.	The Service Provider will not, at any time during the term
of the Agreement, use or disclose any trade secrets or proprietary or confidential information in such manner that may breach any confidentiality
or other obligation that the Service Provider owes to any former employer or other third party, without their prior written consent.

 

		8.2.	The Service Provider warrants that he has the full right
to assign the Company’s IP Rights and the associated rights, titles and interests and that the Service Provider has not made, and
will not make, any agreement in conflict with this paragraph or Section 5 above.

 

	9.	General

 

		9.1.	The Service Provider shall not assign any of his rights and
obligations hereunder without the prior written consent of the Company, and any attempt to do so shall be null and void.

 

		9.2.	No behavior by either party hereto shall be deemed to constitute
a waiver of any rights according to this Agreement, a waiver of or consent to any breach or default in respect of any of the terms hereof,
or a change, invalidation or addition to any term, unless expressly made in writing.

 

		9.3.	All disputes with respect to this Agreement shall be determined
in accordance with the laws of Israel. The competent courts of Tel-Aviv, Israel shall have exclusive jurisdiction to hear any such dispute
and no other courts shall have any jurisdiction whatsoever in respect of such disputes.

 

		9.4.	The terms of this Agreement shall be interpreted in such
a way as to give them maximum enforceability at law. The unenforceability of any term (or part thereof) shall not affect the enforceability
of any other part of this Agreement.

 

		9.5.	The Service Provider hereby declares that he is aware that
the Company shall rely on the statements and representations in this Agreement, including the absence of employer-employee relationship,
in managing its businesses and providing due diligence to third parties regarding the conditions and the obligations of the Company.
In addition, the Service Provider undertakes that it is aware that third parties might rely on the declarations and the representations
in this Agreement.

 

		9.6.	This Agreement, contains the entire agreement and understanding
between the parties with respect to the subject matter contained herein, and supersedes all prior discussions, agreements, representations
and understandings in this regard. This Agreement shall not be modified except by an instrument in writing signed by both parties.

 

		9.7.	Provisions intended to survive the termination of this Agreement,
including but not limited to Sections ‎3, ‎5, ‎6 and ‎7 herein, shall so survive.

 

		9.8.	Each notice or demand given by one party to the other pursuant
to this Agreement shall be given in writing and shall be sent by registered mail to the other party at the address shown at the beginning
of this Agreement (unless another address has been notified in accordance with this Section), or delivered by hand. Any such notice or
demand shall be deemed given at the expiration of three days from the date of mailing by registered mail (against a proper certification)
or immediately if delivered by hand (against a signature of acceptance).

 

		9.9.	Without derogating from any relief to which the Company is
entitled to pursuant to any law or agreement, the Company may set off any amount which the Service Provider owes it pursuant to this
Agreement or any other source from any sum that the Service Provider is entitled to receive from the Company, from whatever source.

 

		9.10.	The Service Provider hereby declares that this Agreement
is signed by it upon its request, after he has checked all its rights and obligations deriving from this Agreement, according to any
law and after it has investigated all its rights pursuant to this Agreement against the Company.

 

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IN WITNESS WHEREOF, the parties have executed
this Agreement as of the above date.

 

		 	
	Noam Band	 	Regentis Biomaterials Ltd.
	 	 	 	 
	 	 	By:	Dr. Ehud Geller
	 	 	Title:	Chairman of the Board

 

 

8Exhibit 10.8

 

SERIES B PREFERRED SHARE PURCHASE AGREEMENT

 

THIS SERIES B PREFERRED SHARE
PURCHASE AGREEMENT (the “Agreement”) is entered into on and as of this 2nd day of August, 2007,
by and among (i) Regentis Biomaterials Ltd., a company organized under the laws of the State of Israel, Israeli Company
No. 513585240, located at Matam-Advanced Technology Center, Building No. 30, POB 15054, Haifa 31905, Israel (the “Company”);
(ii) The Technological Incubator Founded by the Technion R&D Foundation Ltd., a company organized under the laws of
the State of Israel, Israeli Company No. 510340677, located at Matam-Advanced Technology Center, Building No. 30, POB 15054, Haifa 31905,
Israel (the “Incubator”); (iii) Dr. Dror Seliktar of Bio-Medical Engineering Department, Technion,
Technion City, Haifa 32000, Israel (“Seliktar”); (iv) Mr. Yehiel Tal of 6 Hamaish Street, Zichron Yaakov,
Israel (“Tal”) (Seliktar and Tal each a “Founder” and collectively the “Founders”);
and (iv) the investors listed on Schedule A to this Agreement (each, an “Investor” and collectively,
the “Investors”; the Company, the Founders, the Incubator and the Investors shall each be referred to hereinafter
as a “Party” and collectively as the “Parties”).

 

RECITALS: 

 

WHEREAS, the Company
is engaged, within the framework of the Incubator, in a project for the development, manufacturing and marketing of a new method for the
development, manufacturing and marketing of a new biosynthetic biomaterial to stimulate the regeneration of bone and/or cartilage and/or
other aesthetics applications as more fully set forth in US Patent Application No. 60/530,917 (the “Invention”), and
for the creation, development, manufacturing, marketing and sale or other distribution of commercial products based on the Invention or
derived therefrom (the “Products”) or on any other Intellectual Property (as defined below) related to the Invention
or the Products.

 

WHEREAS, the Board
of Directors of the Company (the “Board”) has determined that it is in the best interests of the Company to raise additional
capital of up to US $7,500,000 (including the Bridge Loan as defined below), by means of the issuance (i) at the Initial Closing (as defined
below) of 127,653 Series B Preferred Shares of the Company, each having a nominal value of NIS 0.01 (the “Initial Preferred B
Shares”), at a price per share of $28.00164 (the “Price Per Share”) including the 2,662 Series B Preferred
Shares of the Company, each having a nominal value of NIS 0.01 being issued as a result of the discount in the conversion of the Bridge
Loan in accordance with the terms of the Bridge Loan Agreement, reflecting a pre-money valuation of the Company, on a Fully Diluted Basis
(as defined below), as of such Initial Closing, of US $5,000,000, and (ii) at the Milestone Closing (as defined below) – of
up to 142,850 Series B Preferred Shares of the Company, each having a nominal value of NIS 0.01 (“Milestone Preferred B Shares”),
at the Price Per Share; all on the terms and conditions more fully set forth in this Agreement; and

 

WHEREAS, certain
of the Investors, indicated as such on Schedule B, (the “Lending Purchasers”) have previously made available
to the Company a convertible bridge loan in an aggregate amount of US$298,000 plus interest (the “Bridge Loan”) pursuant
to the terms of the bridge loan agreement specified on Schedule B by and among the Company and such respective Lending Purchasers
listed therein (the loan agreement and the amendment thereto, the “Bridge Loan Agreement”); and

 

WHEREAS,the Investors
desire to invest in the Company on the terms and subject to the conditions set forth in this Agreement; and

 

     

     

    

 

NOW, THEREFORE, in
consideration of the premises and the mutual promises herein made, and in consideration of the representations, warranties, and covenants
herein contained, and intending to be legally bound hereby, the Parties hereby agree as follows:

 

1.  The
Transaction

 

		1.1.	Issue and Purchase of Initial Preferred B Shares.

 

1.1.1  Subject
to the terms and conditions hereof, at the Initial Closing (as defined in Section 2.1 below), the Company shall issue and sell to the
Investors, and the Investors shall purchase from the Company, severally and not jointly, the Initial Preferred B Shares, having the rights,
preferences and privileges set forth in the 2nd Amended and Restated Articles of Association of the Company (the “2nd
Amended Articles”) at the Price Per Share for a total aggregate purchase price of US$3,500,000 (including the Bridge Loan) (the
“Initial Investment”). The number of Initial Preferred B Shares to be purchased by each Investor and each of their
respective amounts of the aggregate purchase price for such Initial Preferred B Shares (as defined below), shall be as set forth in Schedule C
attached hereto.

 

1.1.2  As
part of the Initial Investment, an aggregate amount equal to the principle amount of the Bridge Loan shall be converted into 10,642 Preferred
B Shares in accordance with the terms of the Bridge Loan Agreements in consideration of the full and final discharge of the Loan Amount
by the Lending Purchasers, in accordance with the terms of the Bridge Loan Agreement. The interest which has accrued pursuant to the Bridge
Loans amounting to US$12,906.76, which shall not bear any further interest or linkage differentials from the date hereof (the “Interest”),
shall be repaid in cash immediately prior to the Initial Closing. As of Closing, the share holdings of the Company’s share capital
shall be as set forth in the Company’s capitalization table

 

1.1.3  The
Company and the Lending Purchasers hereby represent, warrant and agree that: (a) upon the Initial Closing, the Loan Agreement shall automatically
terminate and be of no further force and effect; (b) the principle amount of the Bridge Loan shall be deemed to have been fully converted
into Preferred B Shares in accordance with Sections 1.1.2 above (c) the Interest shall be repaid in accordance with Sections 1.1.2 above
and (d) as of the Initial Closing, the Lending Purchasers will have no outstanding loans to, or debts due to them from, the Company and
no claims whatsoever under the Loan Agreement (including, but not limited to, as to the number of Preferred B Shares issued to them at
the Initial Closing). The Company represents further that as of the Initial Closing there will be no outstanding loans which are convertible
into securities of the Company.

 

		1.2.	Milestone Investment 

 

1.2.1  In
the event that, on or prior to eighteen (18) months post the Initial Closing (the “Due Date”), (i) the Company meets,
to the satisfaction of the majority in interest of the Investors (the “Investors Majority”), the milestone set forth
in Schedule 1.2.1 hereof (the “Milestone”), or (ii) satisfaction of the Milestone has been waived by the Investors
Majority, then at the Milestone Closing, the Company shall issue and sell to the Investors, and the Investors shall purchase from the
Company, severally and not jointly, the Milestone Preferred B Shares (the “Milestone Preferred B Shares” and, together
with the Initial Preferred B Shares, the “Purchased Shares”), having the rights, preferences and privileges set forth
in the 2nd Amended Articles, at the Price Per Share and in accordance with the allocation of such Milestone Closing Shares
set forth in Schedule C below (the “Milestone Investment”). The aforesaid number of Milestone Preferred B Shares
as well as the Price Per Share shall be proportionally adjusted for any Recapitalization Event (as defined below) occurring hereafter
prior to the Milestone Closing.

 

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As used herein, the term “Recapitalization
Event” means any split or reverse split of the applicable shares, distribution of share dividend, with respect thereto, or any
other recapitalization, reclassification or similar event resulting in a change of such shares into a different number of shares of the
same class or any other class or classes of shares.

 

1.2.2
Evaluation Period, Participation Notice.

 

(a)  On
or before the Due Date, the Company will inform the Investors in writing, whether or not the Company has successfully achieved the Milestone
(in the event the Company notifies that the Milestone has been satisfied, such notice will include the deliveries set forth in Section
2.4.1 below). During a 30-day period following receipt by the Investors of such Company’s notice (the “Evaluation Period”),
the Investors shall be entitled to examine the accomplishment by the Company of the Milestone to their satisfaction, and the Company shall
allow the Investors full access to any relevant information concerning the Milestone and shall provide
each Investor with any information, documentation or oral clarifications reasonably required by such Investor for the evaluation and determination
of the Milestone satisfaction.

 

(b)  On
or before expiration of the Evaluation Period, the Investor Majority will notify the Company, in writing (and the Company will forward
same to all other Investors), whether or not the Investor Majority approves – or waives - the satisfaction of the Milestone (the
parties agree that the failure of the Investor Majority to so notify the Company within the Evaluation Period, shall be deemed as a non-approval
by the Investors Majority of the satisfaction of said Milestone).

 

(c)  Milestone
Confirmation; Allocation of Milestone Preferred B Shares. In the event that, on or before expiration of the Evaluation Period, the
Investors Majority shall have either approved or waived, in writing, the satisfaction of the Milestone by the Company, then the Company
shall so inform, in writing, all of the Investors (“Milestone Confirmation Notice”). In such an event, the allocation
of the Milestone Preferred B Shares which will be issued and sold by the Company at the Milestone Closing shall be made according to Schedule
C.

 

(d)  Non-Confirmation
of Milestone. In the event that by the Due Date the Company shall not have satisfied the Milestone, or that, by the end of the Evaluation
Period, the Investors Majority shall have not approved or waived, in writing, the satisfaction of the Milestone by the Company, then the
Company shall so inform, in writing, all of the Investors (“Milestone Non-Confirmation Notice”), and in such event the
obligation of each of the Investors to invest in the Company the Milestone Investment and the obligation of the Company to issue to any
Investor the Milestone Preferred B Shares shall terminate and the Company shall not be entitled to consummate the Milestone Closing. In
such an event, this Agreement shall only govern the issuance of the Initial Preferred B Shares in consideration of the Initial Investment.

 

1.2.3  Failure
to Achieve Device Designation.

 

In the event that by the end of a four (4) month
period commencing on the Initial Closing, the Company shall not have obtained a device designation in Europe and in the United States
for the cartilage repair product, then the Company shall so inform all the members of the Board of Directors of the Company in writing
and within seven (7) days of such notice, the Board shall hold a meeting in which the implications of such a failure would be discussed
in light of and in accordance with the terms of the approved Budget and Plan (as defined below).

 

    3

     

    

 

		1.3.	ESOP Reserve. 

 

1.3.1  Immediately
prior to the Initial Closing, the Company shall reserve an additional 67,360 Ordinary A Shares for issuance to employees, consultants,
officers, or directors of the Company and/or its subsidiaries pursuant to any current or future share option plan(s) and arrangements
approved (or which may be approved hereafter) by the Board and with respect to any such plans which are adopted subject to Section 102
of the Israeli Tax Ordinance - submitted and approved by the Israeli Tax Authorities (collectively, “ESOP”) totaling
88,959 Ordinary A Shares reserved for issuance under the ESOP, such additional 67,360 Ordinary A Shares constituting 15% of the Company’s
share capital on a Fully Diluted Basis as of immediately following the Milestone Closing (“ESOP Reserve”). As used herein,
the term “Fully-Diluted Basis” means a calculation of the Company’s share capital, taking into account (i) all shares
of the Company issued and outstanding as of the date to which such calculation refers, (ii) all shares of the Company issuable upon conversion,
exercise or exchange of all options, warrants, convertible securities, anti-dilution rights, adjustments and other rights to acquire shares
of the Company outstanding as of the date to which such calculation refers, and (iii) all shares of the Company reserved for issuance
under share incentive plans or arrangements, as of the date to which such calculation refers, whether or not any options therefor are
then outstanding.

 

1.3.2  Other
than as may otherwise be determined by the Board, all options granted under the ESOP shall be subject to vesting as follows: (i) 25% shall
be vested one year after their respective grant date, and (ii) 75% shall vest over three (3) additional years after the respective grant
date, in twelve (12) equal quarterly installments thereafter.

 

1.3.3
Taking into consideration the future specific plans to recruit and build the management team of the Company, the Board shall consider
an additional increase of up to ten percent (10%) of the ESOP Reserve.

 

2.
Closing of Issue and Purchase

 

2.1.  Initial
Closing. The closing of the transactions contemplated in Section 1.1 above, will take place at a closing (the “Initial Closing”)
to be held at the offices of Kantor & Co., Law offices, 14 Abba Hillel Silver Rd, Ramat Gan, within three (3) business days following
completion of the transactions set forth in Section 2.2 below and satisfaction (or waiver by the relevant Party) of the conditions set
forth in Section 2.5 below, commencing at 11:00 a.m., local time, or at such other time or place as the Company and the Investors
shall mutually agree upon (orally or in writing).

 

2.2.  Deliveries
and Transactions at the Initial Closing. At the Initial Closing, the following transactions shall occur, which transactions shall
be deemed to take place simultaneously and no transaction shall be deemed to have been completed or any document delivered until all such
transactions have been completed and all required documents delivered:

 

2.2.1.  The
Company shall deliver to the Investors the following documents or cause the following actions to be completed:

 

(a)  Shareholders
Resolutions. Duly executed resolutions of the shareholders of the Company, adopted by a unanimous written resolution, in the form
attached as Schedule 2.2.1(a)(A) hereto, (i) approving the modification of the share capital of the Company in accordance with
the capitalization set forth in the 2nd Amended Articles, (ii) replacing the existing 1st Amended and Restated
Articles of Association with the 2nd Amended Articles, in the form attached to Schedule 2.2.1(a)(B), (iii) approving
the execution, delivery and performance by the Company of this Agreement and all Ancillary Agreements (as defined below), and the consummation
of all transactions contemplated hereby and thereby (iv) appointing Dr. Ehud Geller and Mr. Eli Hazum designated for appointment by Medica
as members of the Board effective as of the Initial Closing and (v) reaffirming the appointment of Yehiel Tal, Jeffrey Dykan as members
of the Board; together with duly completed notices of such actions in form and substance ready for immediate filing after the Initial
Closing with the Israeli Registrar of Companies. Such notice shall be filed with the Israeli Registrar of Companies within two (2) days
of the Initial Closing and Company shall provide the Investors with proof of filing within such two (2) day period.

 

    4

     

    

 

(b) Board
Resolutions. Duly executed resolutions of the Board, adopted by a unanimous written resolution, in the form attached as Schedule
2.2.1(b)1 hereto, (i) approving the execution, delivery and performance by the Company of this Agreement and all Ancillary
Agreements (as defined below), and the consummation of all transactions contemplated hereby and thereby, including, inter alia, the
issuance and sale by the Company to the Investors of the Initial Preferred B Shares, and, as applicable, the Milestone Preferred B
Shares, all in accordance with the terms and conditions of this Agreement without the necessity to adopt any additional resolutions
other than as set forth in Section 2.4.2 below; (ii) reserving for issuance such number of Ordinary Shares as may be necessary
from time to time to allow the conversion in full of all of the Purchased Shares then outstanding; (iii) reserving the number of
Ordinary Shares constituting the ESOP Reserve, (iv) adopting new signatory rights on behalf of the Company, in accordance with the
signatory rights set forth in Schedule 2.2.1(b)2; (v) approving the form of indemnification agreements in the form attached
hereto as Schedule 2.2.4 and the delivery of such to the directors designated for appointment by the Investors; together with
a duly completed notice of issuance of the Initial Preferred B Shares in form and substance ready for immediate filing after the
Initial Closing with the Israeli Registrar of Companies. Such notice shall be filed with the Israeli Registrar of Companies within
two (2) days of the Initial Closing and Company shall provide the Investors with proof of filing within such two (2) day period.

 

(c)  Share
Certificates. Validly executed share certificates, dated as of the Initial Closing date, covering the Initial Preferred B Shares issued
in the names of the respective Investors, in the form attached as Schedule 2.2.1(c) hereto.

 

(d)  Shareholder
Register. A copy, duly certified by an officer of the Company and dated as of the Initial Closing date, of the Company’s shareholders
register, in the form attached as Schedule 2.2.1(d) hereto, reflecting the registration by the Company of the issuance of the Initial
Preferred B Shares to the Investors, in the respective numbers set forth opposite the name of each Investor on Schedule A.

 

(e)  Shareholder
Waivers. Validly executed waivers by all existing shareholders of the Company and by any other applicable third party, in the form
attached hereto as Schedule 2.2.1(e), with respect to any preemptive rights, first refusal rights, anti-dilution rights
or similar rights such shareholders or third parties hold in connection with the transactions contemplated herein, pursuant to the existing
1st Amended and Restated Articles of Association of the Company or any applicable law or agreement.

 

(f)  Compliance
Certificate. A certificate duly executed by the chief executive officer of the Company, dated as of the Initial Closing, in the form
attached hereto as Schedule 2.2.1(f), certifying that the representations and warranties set forth in Section 3 hereof are true
and correct as of and through the Initial Closing, that the Company has performed and complied with all of its respective covenants, agreements
and undertakings set forth herein and that since the date of execution of the Agreement, there has not been a material deterioration in
the financial or business condition or prospects of the Company;

 

(g)  Legal
Opinion. An opinion of Goldsobel and Kirshen, Law Offices, legal counsel to the Company, dated as of the Initial Closing, in the form
attached hereto as Schedule 2.2.1(g);

 

(h)  Chief
Scientist Compliance. An evidence to the effect that all notification or approval requirements by the Office of Chief Scientist within
the Israeli Ministry of Industry and Commerce, with respect to all transactions contemplated hereby to be performed at the Initial Closing
and the Milestone Closing, have been duly complied with by the Company (in form and substance reasonably satisfactory to the Investors)
prior to the Initial Closing. Each Investor (other than those of the Investors who have previously delivered to the Company the following
undertaking) who is not a legal entity registered under the laws of the State of Israel, shall execute and deliver an Undertaking to the
Chief Scientist in the form attached hereto as Schedule 2.2.1(h).

 

    5

     

    

 

(i)  Director
Appointment Notices. A duly completed notice of the action set forth in Section 2.2.6 below in form and substance ready for immediate
filing after the Initial Closing with the Israeli Registrar of Companies. Such notice shall be filed with the Israeli Registrar of Companies
within two (2) days of the Initial Closing and Company shall provide the Investors with proof of filing within such two (2) day period

 

2.2.2.  Conversion
of Bridge Loans. Automatically, and without any further action by the Company or the Lending Purchasers, the Bridge Loans shall be
converted into a portion of the Initial Preferred B Shares pursuant to Section 1.1.2 above and as set forth in Schedule C hereto,
and the Lending Purchasers shall have no further claims for the principle amounts under the Bridge Loan Agreements. The Interest shall
be repaid in cash immediately prior to the Closing pursuant to Section 1.1.2 above.

 

2.2.3.  Payment
of Consideration. Each Investor shall cause the transfer to the Company of its aggregate Price Per Share for the Initial Preferred
B Shares being issued to it, in the respective amounts set forth opposite the name of such Investor in Schedule C hereto, by wire
transfer in accordance with written instructions of the Company attached hereto as Schedule 2.2.2. The obligation of each Investor
hereunder shall be several and not joint. Payment by each Investor of such aggregate Price Per Share shall be made in US Dollars, or,
at the election of such Investor, in the New Israeli Shekel equivalent thereof, calculated in accordance with the official representative
rate of exchange of the US Dollar into NIS last published by the Bank of Israel and known at the time of actual payment under this Agreement.
The Company and the Lending Purchasers hereby acknowledge and agree that upon the Initial Closing, the Bridge Loan Agreement shall automatically
terminate and be of no further force or effect and the Bridge Loan granted thereunder shall be applied against the applicable purchase
price and be deemed to have been repaid in full.

 

2.2.4.  Investors’
Rights Agreement. The Company and the Investors shall execute and deliver the Investors’ Rights Agreement in the form attached
hereto as Schedule 2.2.3 (the “Investors Rights Agreement”).

 

2.2.5.  Indemnification
Agreement. The Company and each of the directors of the Company as of the Initial Closing (including without limitation each of the
persons appointed as director of the Company under Section 2.2.6 hereof) shall have executed indemnification agreements in the form attached
hereto as Schedule 2.2.4.

 

2.2.6.  Management
Rights Letters. The Company shall deliver to each of the Investors a Management Rights Letter, in the form attached as Schedule
2.2.5 hereto, dated as of the Initial Closing date, duly signed by the Company.

 

2.2.7.  Directors
Appointment and Resignation. Medica (as defined in Schedule A) shall have designated for appointment Dr. Ehud Geller and Mr. Eli Hazum
as members of the Board effective as of the Initial Closing. Mr. Benny Soffer, Ms. Niza Kardish and Dror Seliktar have resigned from their
positions as members of the Board of Directors, effective as of the Initial Closing.

 

2.2.8.
Employment Agreements. The Company shall deliver to each of the Investors copies of employment agreements, attached hereto
as Schedules 2.2.7(i) and 2.2.7(ii), with each of the Founders which have been approved in advance by the Investors and the Board
of Directors of the Company.

 

2.2.9.  Amendment
to the Founders Agreement. The Company shall deliver to each of the Investors a copy of the signed amendment (which have been approved
in advance by the Investors) to the Founders Agreement dated September 4, 2004 by and between the Founders, the Incubator and the Technion
Research and Development Foundation Ltd., a copy of which is attached hereto as Schedule 2.2.8.

 

    6

     

    

 

2.2.10.  Termination
of Finders Agreements. The Company shall have terminated (i) the Finders Agreement entered into by the Company and Brian J. Cole dated
January 10th, 2006 and (ii) the Finders Agreement entered into with Harlan Jacobs dated May 31st, 2006.

 

2.3.  Milestone
Closing. The closing of the transactions contemplated in Section 1.2 above, if any, will take place at a closing (the “Milestone
Closing”) to be held at the offices of Kantor & Co., Law Offices, 14 Abba Hillel Silver Rd., Ramat Gan, within three
(3) business days following completion of the transactions set forth in Section 2.4 below and satisfaction (or waiver by the relevant
Party) of the conditions set forth in Section 2.5 below, commencing at 11:00 a.m., local time, or at such other time or place as
the Company and the Investors shall mutually agree upon (orally or in writing).

 

2.4. Transactions
at Milestone Closing. At the Milestone Closing, the following transactions shall occur, which transactions shall be deemed to take
place simultaneously and no transaction shall be deemed to have been completed or any document delivered until all such transactions have
been completed and all required documents delivered:

 

2.4.1.  The
Company shall have delivered to the Investors written evidence, in form and substance satisfactory to the Investors Majority, demonstrating
that the Company has achieved the Milestone, unless achievement of the Milestone has been waived by the Investors Majority in writing,
in accordance with the provisions of Section 1.2.2 above.

 

2.4.2.  The
Company shall have delivered to the Investors true and correct copies of the resolutions adopted by the Board (a) confirming achievement
of the Milestone, receipt of the written approval of the Milestone by the Investors Majority or, as applicable, receipt of the written
waiver of the Milestone by the Investors Majority.

 

2.4.3.  The
Company shall have delivered validly executed share certificates, dated as of the Milestone Closing date, covering the Milestone Preferred
B Shares issued in the names of the respective Investors, in the form attached as Schedule 2.2.1(c) hereto.

 

2.4.4.  The
Company shall have delivered a copy, duly certified by an officer of the Company and dated as of the Milestone Closing date, of the Company’s
shareholders register, in the form attached as Schedule 2.2.1(d) hereto, reflecting the registration by the Company of the issuance
of the respective numbers of Milestone Preferred B Shares to the Milestone Investors, together with a duly completed notice of issuance
of the Milestone Preferred B Shares in form and substance ready for immediate filing after the Milestone Closing with the Israeli Registrar
of Companies. Such notice shall be filed with the Israeli Registrar of Companies within two (2) days of the Milestone Closing and Company
shall provide the Investors with proof of filing within such two (2) day period.

 

2.4.5.  The
Company shall have delivered to the Investors a certificate, duly executed by the Chief Executive Officer of the Company (or if no such
officer is incumbent, a director of the Company), in the form attached hereto as Schedule 2.4.5, certifying that the representations
and warranties set forth in Section 3 hereof are true and correct as of and through the Milestone Closing, that the Company has performed
and complied with all of its respective covenants, agreements and undertakings set forth herein and that since the Initial Closing, there
has not been a material deterioration in the financial or business condition or prospects of the Company.

 

    7

     

    

 

2.4.6.  Payment
of Consideration. Each Investor shall cause the transfer to the Company of its aggregate Price Per Share for the Milestone
Preferred B Shares being issued to it at the Milestone Closing, by wire transfer in accordance with written instructions of the Company
attached hereto as Schedule 2.2.2. The obligation of each Investor hereunder shall be several and not joint. Payment by each Investor
of such aggregate PPS shall be made in US Dollars, or, at the election of such Investor, in the New Israeli Shekel equivalent thereof,
calculated in accordance with the official representative rate of exchange of the US Dollar into NIS last published by the Bank of Israel
and known at the time of actual payment under this Agreement.

 

2.5. Conditions of
Investors to Closing. The obligations of each Investor to purchase the Initial Preferred B Shares and the Milestone Preferred B Shares
and to transfer funds at the Initial Closing and the Milestone Closing (each, a “Closing”) are subject to the
fulfillment at or before such applicable Closing of the following conditions precedent (to the extent indicated below), any one or more
of which may be waived in whole or in part by the Investor, which waiver shall be at the sole discretion each of the Investors:

 

2.5.1.  Representations
and Warranties. The representations and warranties made by the Company and the Founders in this Agreement shall have been true and
correct when made, and shall be true and correct as of the Initial Closing or, as applicable, as of the Milestone Closing as if made on
the Initial Closing or, as applicable, as of the Milestone Closing.

 

2.5.2.  Covenants.
All covenants, agreements, and conditions contained in this Agreement to be performed or complied with by the Company or the Founders
prior to the Initial Closing and/or Milestone Closing, as the case may be, shall have been performed or complied with by the Company or
the Founders, as the case may be, prior to or at such Closing.

 

2.5.3.  Consents,
etc. The Company shall have secured all permits, consents and authorizations that shall be necessary or required lawfully to consummate
this Agreement and to issue the Initial Preferred B Shares to each Investor at the Initial Closing and the Milestone Preferred B Shares
to each Investor at the Milestone Closing, as applicable.

 

2.5.4.  Delivery
of Documents. All of the documents to be delivered by the Company pursuant to Section 2.2 and 2.4 shall have been delivered to the
Investors. All other actions and transactions set forth in Sections 2.2 and 2.4 shall have been completed on or prior to the applicable
Closing.

 

2.5.5.  Proceedings
and Documents. All corporate and other proceedings in connection with the transactions contemplated by this Agreement shall be satisfactory
in substance and form to each of the Investors and their counsel, and each of the Investors and their counsel shall have received all
such counterpart originals or certified or other copies of such documents as the Investors or their counsel may reasonably request.

 

2.5.6.  Ordinary
Course of Business. From the signing of this Agreement through the
Initial Closing or, as applicable, the Milestone Closing, the Company has not taken, and has not agreed or resolved to take, any action
which is outside the ordinary course of its business consistent with past custom and practice (including with respect to quantity and
frequency)

 

    8

     

    

 

2.6.  Conditions
of the Company to Closing. The Company’s obligations to sell and issue the respective Purchased Shares at the applicable Closing are
subject to the fulfillment at or before such Closing of the conditions that (a) all covenants, agreements and conditions contained in
this Agreement to be performed, or complied with, by the Investors, as applicable, prior to such Closing, shall have been performed or
complied with by such Investors prior to or at such Closing, and (b) the representations and warranties made by the Investors in this
Agreement shall have been true and correct when made, and shall be true and correct as of the date of the Initial Closing and, as applicable,
the Milestone Closing, which conditions may be waived in whole or in part by the Company, and which waiver shall be at the sole discretion
of the Company, and (c) the Investors shall have paid to the Company the aggregate Price Per Share, payable thereto hereunder at such
Closing, in immediately available funds.

 

3.
Representations and Warranties of Company and Founders

 

The Company and each of the
Founders, jointly and severally, hereby represent and warrant to the Investors at the Initial Closing and, as applicable, as of the Milestone
Closing, if and when occurs, and acknowledge that the Investors are entering into this Agreement in reliance thereon, as follows, except
as set forth in the Schedule of Exceptions attached hereto as Schedule 3 (section numbers in this Schedule of Exceptions
correspond to the section numbers in this Agreement):

 

3.1.  Organization.
The Company is a private company duly incorporated and validly existing under the laws of the State of Israel.

 

3.2.  Corporate
Power and Authority; Insolvency. The Company has all requisite power and authority (corporate and other) to own and operate its properties
and assets, perform all its obligations under all agreements to which it is party or by which it is bound, and to carry on its business
as presently conducted and as proposed to be conducted. The Company has not taken any action or failed to take any action, which action
or failure could preclude or prevent the Company from conducting its business after the Initial Closing or the Deferred Closing, as applicable,
as presently conducted and as proposed to be conducted. (i) No order has been made or petition presented or resolution passed for the
liquidation or reorganization of the Company, nor has any distress, execution or other process been levied against the Company or action
taken to repossess goods in the Company’s possession; (ii) No steps have been taken for the appointment of an administrator, trustee
or receiver of any part of the Company’s business; (iii) No creditor has exercised its rights with respect to Security Interest
(as defined below) in any of Company’s assets and there are no circumstances likely to cause such an action to occur; (iv) The Company
has not been a party to any transaction which could result in a winding up thereof, and (v) The Company has not made or proposed any arrangement
or composition with its creditors or any class of its creditors. The Company is duly qualified to do business and is in good standing
in each jurisdiction in which the Company currently conducts or plans to conduct business or in which it currently owns or leases or plans
to own or lease property. “Security Interest” - means any mortgage, pledge, lien, hypothecation, encumbrance,
charge, claim or other security interest of any kind or character, direct or indirect, whether accrued, absolute, contingent or otherwise.

 

3.3.  Capitalization

 

3.3.1.  The
authorized share capital of the Company immediately prior to the Initial Closing shall be NIS 30,000, consisted of:

 

(a)  2,675,000
Ordinary A Shares, with a nominal value of NIS 0.01 each, (the “Ordinary A Shares”) of which 41,734 Ordinary A Shares
are issued and outstanding, 318,371 Ordinary A Shares are reserved for issuance upon conversion of the Series A Preferred Shares (as defined
below) and the Series B Preferred Shares and 88,959 Ordinary A Shares are reserved for issuance under the ESOP, with respect to 21,599
of which, promises to grant options under the ESOP have been made.

 

    9

     

    

 

(b)  50,000
Series A Preferred Shares, with a nominal value of NIS 0.01 each (“Series A Preferred Shares”), of which 47,868 are issued
and outstanding. The rights, privileges and preferences of the Series A Preferred Shares are as set forth in the 2nd Amended
Articles.

 

(c)  275,000
Preferred B Shares, with a nominal value of NIS 0.01 each (the “Series B Preferred Shares”) (the Series A Preferred
Shares and the Series B Preferred Shares are collectively referred to herein as the “Preferred Shares”), none of which
are issued and outstanding and (i) up to 127,653 of which shall be issued at the Initial Closings (including the 2,662 Series B Preferred
Shares issued upon conversion of the for the discount under the Bridge Loans) and (ii)142,850 of which shall be issued at the Milestone
Closing, if and as applicable, in accordance with this Agreement. The rights, privileges and preferences of the Preferred B Shares are
as set forth in the 2nd Amended Articles.

 

3.3.2.  All
outstanding share capital of the Company is free and clear of any Security Interests, restrictions, right, options to purchase, proxies,
voting trusts and other voting agreements, calls or commitments of every kind. All issued and outstanding shares of the Company have been
duly authorized and are validly issued, fully paid, and non-assessable and were issued in compliance with all applicable Israeli laws.
None of the issued and outstanding shares of the Company have been issued in violation of any preemptive, subscription or other right
of any party Person to acquire securities of the Company. All of the issued and outstanding shares of the Company are free and clear of
any restrictions on transfer, taxes or Security Interests.

 

3.3.3.  Except
for the transactions contemplated by this Agreement and as set forth in the capitalization table set forth as Section 3.3.3(i)
of the Schedule of Exceptions, there are no outstanding or authorized options, warrants, purchase rights, subscription rights, conversion
rights, exchange rights, preemptive rights, rights of first refusal, or other rights or securities, of any nature whatsoever, or other
contracts, promises or commitments, written or oral, that could require the Company or, to the Company’s and Founders’ best knowledge,
any shareholder of the Company to sell, transfer or otherwise dispose of, or that could require the Company to issue, sell, or otherwise
cause to become outstanding, any share of the Company (collectively, “Equity Related Rights”), there are no securities
convertible into, exchangeable or exercisable for or evidencing the right to subscribe for equity securities of the Company, and, as of
the Initial Closing, there shall not be outstanding - by reason of the execution, delivery or performance of this Agreement or by any
other reason - any of the foregoing Equity Related Rights in or with respect to the Company’s share capital (whether granted by
the Company or, to the Company’s and the Founders’ best knowledge, by any shareholder of the Company) or claims possessed by any
person and enforceable against the Company in law or in equity, to compel such an issuance, adjustment or transfer of the Ordinary A Shares,
Ordinary B Shares or Preferred Shares (or any options, warrants, preemptive rights or other rights or securities, of any nature whatsoever,
convertible into or exchangeable for shares of the Company). There are no outstanding share appreciation(s), phantom share(s), profit
participation(s), or similar rights with respect to the Company. There are no voting trusts, proxies, or other agreements or understandings
with respect to the voting of any share capital of the Company.

 

3.3.4.  The
Company has not adopted or approved any plan for the benefit of its officers, employees, consultants or directors which requires or permits
the issuance, sale, purchase, or grant of any equity securities of the Company or any other securities convertible into, exercisable or
exchangeable for or evidencing the right to subscribe for any such shares or securities.

 

    10

     

    

 

3.3.5.  Other
than as stated in Section 3.3.5 of the Schedule of Exceptions, the Company is not a party or subject to any agreement or understanding,
that is in force to date or through the Initial Closing or at any time following the Initial Closing, written or oral, and there is no
agreement or understanding, written or oral, between any third parties, that affects or relates to the equity of the Company.

 

3.3.6.  As
of each Closing, the respective Purchased Shares issued to the Investors, pursuant to this Agreement, will be, when issued, sold and delivered
in accordance with the terms of this Agreement, for the consideration expressed herein, as applicable, duly and validly authorized and
issued, fully paid up and non-assessable, and issued in compliance with all applicable Israeli laws, including Israeli securities laws,
free and clear of any limitation whatsoever, including, without limitation, free and clear of any Security Interests, loans, options and
third party rights, claims, restrictions or interests of any kind, contractual or otherwise, restrictions on transfer, preemptive or similar
rights other than as set forth in this Agreement, the 2nd Amended Articles or the Investors Rights Agreement.

 

3.3.7.  As
of each Closing, the Ordinary Shares issuable upon conversion of the then outstanding Preferred Shares, in accordance with the 2nd
Amended Articles, shall be duly authorized and reserved for issuance by all necessary corporate actions and, when issued and paid-for
in accordance with the 2nd Amended Articles and this Agreement, will be duly and validly issued, fully paid, non-assessable
and issued in compliance with all applicable Israeli laws, free and clear of any Security Interests, loans, options and third party rights,
claims, restrictions or interests of any kind, contractual or otherwise, restrictions on transfer, preemptive or similar rights other
than as set forth in this Agreement, the 2nd Amended Articles or the Investors Rights Agreement

 

3.3.8.  Except
as set forth in the Investors Rights Agreement, the Company is not under any obligation to register for trading on any securities exchange
any of its currently outstanding securities or any of its securities which may hereafter be issued

 

3.4.
Board of Directors; Officers

 

3.4.1.  Prior
to the Initial Closing, the Board consists of five (5) members, whose names are Dr. Dror Seliktar, Yehiel Tal, Jeffrey Dykan, Niza Kardish
and Benny Sofer, of whom Dror Seliktar, Niza Kardish and Benny Sofer shall resign as of the Initial Closing. Section 3.4 of the Disclosure
schedule contains a complete list of the officers of the Company immediately prior to and following the Initial Closing. Other than as
set forth in the Company’s 2ndAmended Articles, the Company has no agreement, obligation or commitment with respect to the
election of any individual to the Board. All agreements (written or oral), with respect to any compensation to be provided to any officers
or directors are listed in Section 3.4 of the Disclosure schedule.

 

3.4.2.  The
Board has no committees.

 

3.5.  Corporate
Documents. Attached hereto as Schedule 3.5 are true, correct and complete copies of the Company’s Certificate of Incorporation
and First Amended Articles of Association which are in effect on the date hereof (the “Corporate Documents”). The Company
is not in default under or in violation of any provision of its Corporate Documents. The Company has submitted to the Investors minutes
of all meetings of directors and shareholders of the Company, and all actions by unanimous written resolutions without a meeting by the
directors and/or the shareholders of the Company since inception of the Company through the date hereof, and accurately reflects all actions
by the Board (and any committee thereof) and/or shareholders of the Company with respect to all transactions referred to in such minutes.

 

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3.6.  Subsidiaries.
The Company has no subsidiaries and does not (i) own any stock or have any equity investment or other interest in, (ii) have the right
to acquire any such interest, or (iii) control or participate in, directly or indirectly, any corporation, association, partnership, joint
venture or any other entity, and has not had such an ownership or control relationship with any such entity.

 

3.7.  Financial
Statements

 

3.7.1.  True,
accurate and complete copies of the Company’s audited annual financial statements of the Company, containing balance sheet and statements
of income, changes in shareholders’ equity, and cash flow as of and for the fiscal year ended December 31, 2006 (“Audited
Financial Statements”), and of the Company’s trial balance sheet and statements of income as of and for the 3 month
period ended March 30, 2007 (“Trial Balance Sheet & P&L”, and, together with the Audited Financial Statements,
the “Financial Statements”), are attached as Schedule 3.7.1 hereto.

 

3.7.2.  The
Financial Statements (including the notes thereto), have been prepared in accordance with US generally accepted accounting principles
consistently applied throughout the periods covered thereby (“GAAP”), and accurately and fairly present the financial
condition of the Company as of such dates and the results of its operations for the periods then ended, except that the Trial Balance
Sheet & P&L have been prepared by the Company and they (i) have neither been reviewed nor audited by the Company’s accountants,
(ii) do not contain any footnotes required by GAAP, and (iii) are subject to year-end adjustments. The Financial Statements are true,
correct and complete in all respects, and are consistent with the books and records of the Company (which books and records are true,
correct and complete), were not affected by any extraordinary, exceptional or nonrecurring item and comply with the requirements of all
applicable laws and regulations. The Company did not receive any notice or allegation that any of the Financial Statements are incorrect
or should be adjusted or amended. Without derogating from the generality of the above, at such dates the Company did not have any material
liabilities, contingent or otherwise, and did not provide guarantees or indemnities to any other entity, except as and to the extent reflected
in the Financial Statements.

 

3.7.3.  Events
Subsequent to December 31, 2006. Except as set forth in Section 3.7.3 of the Schedule of Exceptions, since December 31, 2006
through the Initial Closing, there has not been any material adverse change in the Company’s business and/or financial condition.
Without limiting the generality of the foregoing, since that date:

 

(a)  the
Company has not sold, leased, transferred, or assigned any of its assets, tangible or intangible;

 

(b)  the
Company has not entered into any agreement, contract, lease, or license (or series of related agreements, contracts, leases, and licenses);

 

(c)  no
party (including, inter alia, the Company) has accelerated, terminated, modified, or canceled any agreement, contract, lease, or license
(or series of related agreements, contracts, leases, and licenses) to which the Company is a party or by which it is bound;

 

(d)  the
Company has not imposed any Security Interest upon any of its assets, tangible or intangible;

 

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(e)  the
Company has not made any capital expenditure (or series of related capital expenditures);

 

(f)  the
Company has not made any capital investment in, any loan to, or any acquisition of the securities or assets of, any other party;

 

(g)  the
Company has not issued any note, bond, or other debt security or created, incurred, assumed, or guaranteed any indebtedness for borrowed
money or capitalized lease obligation;

 

(h)  the
Company has not delayed or postponed the payment of accounts payable or other liability or obligation, whether secured or unsecured, whether
accrued or unaccrued, whether absolute or contingent, whether asserted or unasserted, whether liquidated or unliquidated, whether due
or to become due, including any liability for taxes;

 

(i)  the
Company has not canceled, compromised, waived, or released any right or claim;

 

(j)  the
Company has not granted any license or sublicense of any rights under or with respect to any Intellectual Property;

 

(k)  the
Company has not declared, set aside, or paid any dividend or made any distribution with respect to its share capital (whether in cash
or in kind) or redeemed, purchased, or otherwise acquired any of its share capital;

 

(l)  the
Company has not experienced any damage, destruction, or loss (whether or not covered by insurance) to its property, except for ordinary
wear and tear;

 

(m)  the
Company has not made any loan to, or entered into any other transaction with, any of its directors, officers, employees or any affiliate
thereof;

 

(n)  the
Company has not modified the terms of any existing employment or other agreement for the provision of services; or

 

(o)  neither
the Company nor the Founders have committed to any of the foregoing.

 

3.7.4.  Notes
and Accounts Receivable. All notes and accounts receivable of the Company are reflected properly on its books and records and on the
Audited Financial Statements, are valid receivables and, to the Company’s and the Founders’ best knowledge, there is no basis to
subject such receivables to any setoffs or counterclaims.

 

3.7.5.  No
Liabilities. As of the date hereof and except as stated in Section 3.7.5 of the Schedule of Exceptions, the Company does not
have (and as of immediately prior to the Initial Closing the Company will not have) any liability or obligation, whether secured or unsecured,
whether accrued or unaccrued, whether absolute or contingent, whether asserted or unasserted, whether liquidated or unliquidated, whether
due or to become due, and there is no basis for any present or future action, suit, proceeding, hearing, investigation, charge, complaint,
claim, or demand against the Company giving rise to any such liability or obligation.

 

3.8.  Taxes.
The Company has accurately prepared and timely filed all tax returns and reports required by it under applicable law and has paid or made
provision for the payment of all amounts due pursuant to such returns. All tax returns and reports of the Company are true and correct
in all material respects and the Company has paid on time all taxes and other assessments due. None of the tax returns have been audited
by any taxing authority, and the Company has not been advised that any of such Tax Returns will be so audited No deficiency assessment
or proposed adjustment of income or payroll taxes of the Company is pending and the Company has no knowledge, after due inquiry, of any
proposed liability for any tax to be imposed. The Company has not made any elections under applicable laws or regulations (other than
elections that related solely to methods of accounting, depreciation or amortization) that would have an adverse effect on the Company,
its financial condition, its business as presently conducted or as currently proposed to be conducted or any of its properties or assets.
The Company is currently not liable for any tax (whether income tax, capital gains tax, or otherwise).

 

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3.9.  Tangible
Property and Assets

 

3.9.1.  The
Company does not own any real estate property. Section 3.9.1 to the Schedule of Exceptions includes an accurate and complete list
of all tangible property and assets owned or leased by the Company (the “Tangible Property”), specifically stating,
for each such item of tangible property, whether it is owned or leased by the Company. No item of such Tangible Property is shared by
the Company with any other party, and, the Company does not depend for its business upon any assets, facilities or services owned or supplied
by any affiliate of the Company.

 

3.9.2.  Except
as set forth in Section 3.9.2 of the Schedule of Exceptions.

 

(a)  The
Company has good and marketable title to, or a valid leasehold interest in all items of the Tangible Property, free and clear of any limitation
whatsoever, including, without limitation, free and clear of any Security Interests, loans, options and third party rights, claims, restrictions
or interests of any kind, contractual or otherwise, restrictions on transfer, preemptive or similar rights (collectively, “Limitations”).

 

(b)  With
respect to all items of Tangible Property leased by the Company, the Company is in compliance with all terms and conditions applicable
to such leases.

 

(c)  The
Company has the right to use all Tangible Property to the full extent without any Limitation whatsoever.

 

3.10.  Intellectual
Property.

 

3.10.1.  For
purposes of this Agreement, the term “Intellectual Property” shall mean and refer to all intangible legal rights, titles
and interests evidenced by or embodied in or connected or related to (i) all ideas, designs, schemes, processes, know-how, concepts, techniques,
inventions, biological materials, chemicals, synthetic materials, methods, formulae, experience and data, discoveries, or improvements,
regardless of patentability (whether patentable or un-patentable and whether or not reduced to practice), all improvements thereto, and
all patents, patent applications, and patent disclosures, together with all re-issuances, continuations, continuations-in-part, revisions,
extensions, and reexaminations thereof; (ii) all trademarks, service marks, trade dress, logos, trade names, and corporate names, domain
names together with all translations, adaptations, derivations, and combinations thereof and including all goodwill associated therewith,
and all applications, registrations, licenses and renewals in connection therewith; (iii) any work of authorship, regardless of copy-right-ability,
all compilations, all copyrightable works, all copyrights (including the droit morale) and all applications, registrations, and
renewals in connection therewith; (iv) all mask works and all applications, registrations, and renewals in connection therewith, (v) all
trade secrets and business information; (vi) all computer programs, technical data and information, and any other related documentation;
(vii) all other proprietary rights, industrial rights and any other similar rights, in each case on a worldwide basis.

 

3.10.2.  A
complete and accurate list of all Intellectual Property owned by the Company is set forth in Section 3.10.2 of the Disclosure Schedule.

 

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3.10.3.  A
complete and accurate list of all Intellectual Property licensed by the Company from third parties is set forth in Section 3.10.3
of the Disclosure Schedule.

 

3.10.4.  A
complete and accurate list of all Intellectual Property licensed by the Company to third parties is set forth in Section 3.10.4
of the Disclosure Schedule.

 

3.10.5.  The
Company owns and has developed, or has the right to use pursuant to license, sublicense, agreement, or permission, free and clear of all
liens, claims and restrictions, in each case as set forth in Sections 3.10.2 and 3.10.3 of the Disclosure Schedule, all
Intellectual Property used and sufficient for use in the conduct of its business as now conducted and as proposed to be conducted, without,
to the best knowledge of the Company and the Founders, infringing upon or violating any right, lien, or claim of others, including, without
limitation, the Founders and the past employers of the Founders. Each item of Intellectual Property owned or used by the Company immediately
prior to the Initial Closing hereunder will, as of the Initial Closing, be owned or available for use by the Company on identical terms
and conditions immediately subsequent to the Initial Closing hereunder. The Company is not obligated or under any liability whatsoever
to make any payments by way of royalties, fees or otherwise to any owner or licensee of, or other claimant to, any Intellectual Property,
with respect to the use thereof or in connection with the conduct of its business as now conducted or, to the best knowledge of the Company
and the Founders, as currently proposed to be conducted. The Company has never agreed to indemnify any party for or against any interference,
infringement, misappropriation, or other conflict with respect to any Intellectual Property

 

3.10.6.  All
Intellectual Property rights (and all right, title, and interest therein and thereto) evidenced by or embodied in and/or attached, connected
or related to: (i) the Products, including, inter alia, all computer programming codes and algorithms pertaining to the Products and all
user manuals, data sheets, marketing and promotional material, and other documentation (both in written and electronic form) pertaining
to the Products; (ii) any invention or work product developed or created by, or for, the Company; (iii) any part of or any derivative
work of any of the foregoing, including their documentation, is owned solely and exclusively by the Company, free and clear of any Security
Interest, license, or other restriction, including, without limitation, any rights of, or restrictions imposed by the Office of Chief
Scientist, except as set forth in Section 3.10.6 of the Schedule of Exceptions.

 

3.10.7.  Any
and all Intellectual Property of any kind which has been developed, is currently being developed, or will be developed in the future,
by any present or future employee or consultant of the Company in his capacity as such, shall be the property solely of the Company. The
Company has taken security measures to protect the secrecy, confidentiality and value of all such Intellectual Property, which measures
are reasonable and customary in the industry in which the Company operates. All employees and consultants of the Company have entered
into written agreements with the Company, assigning to the Company all rights in Intellectual Property developed in the course of their
employment by or service to the Company, and each of the Company’s employees and other persons who, either alone or in concert with others,
developed, invented, discovered, derived, programmed or designed such Intellectual Property, or who has knowledge of or access to information
about such Intellectual Property, have entered into a written agreement with the Company, in the form set forth as Schedule 3.10.7
(the “Proprietary Information and Non-Competition Agreement”).

 

3.10.8.  To
the Company’s and Founders’ best knowledge, (i) no third party has interfered with, infringed upon, misappropriated, or otherwise come
into conflict with any of the Company’s Intellectual Property rights, and (ii) the Company has not interfered with, infringed upon, misappropriated,
or otherwise come into conflict with or violated any Intellectual Property rights of third parties and will not violate any third party
Intellectual Property in the conduct of its business as now conducted and as proposed to be conducted.

 

    15

     

    

 

3.10.9.  To
the best knowledge of the Company and the Founders, the Company has not violated or by conducting its business as currently proposed would
violate any of the patents, trademarks, service marks, trade names, copyrights or trade secrets or other Intellectual Property rights
of any other person or entity. Neither the Founders nor any of the Company’s employees are obligated under any contract (including licenses,
covenants or commitments of any nature) or other agreement, or subject to any judgment, decree or order of any court or administrative
agency, that would interfere with the use of such person’s best efforts to promote the interests of the Company or that would conflict
with the Company’s business as conducted and as currently proposed to be conducted. Neither the execution nor delivery of the Agreement,
nor the carrying on of the Company’s business by the Founders and other employees of the Company, nor the conduct of the Company’s business
as currently proposed to be conducted, will conflict with or result in a breach of the terms, conditions or provisions of, or constitute
a default under, any contract, covenant or instrument under which the Founders or, to the best knowledge of the Company and the Founders,
any other employees are now obligated. It is not, and will not become, necessary to utilize any inventions of the Founders or the Company’s
other employees (or people the Company currently intends to hire) made prior to their employment by the Company other than those that
have been assigned to the Company pursuant to agreements signed by the Founders and the Proprietary Information and Non Competition agreements
signed by such other employees. None of Company employees and consultants is, and will not be, entitled to any compensation or other payment
in connection with his employment by and/or engagement with the Company or its assignment and/or transfer of Intellectual Property rights
to the Company, except as set forth in his or her employment and/or engagement agreements with the Company.

 

3.11.  Contracts

 

3.11.1.  Section
3.11.1 of the Schedule of Exceptions includes a true and complete list and description of all material contracts and agreements, whether
oral (in which case a written summary setting forth the terms and conditions of each such oral agreement is included therein) or written
that are valid, to which the Company is party or by which it or any of its assets are bound, (the “Company Contracts”).

 

3.11.2.  Without
derogating from the generality of the above and by way of example only, the Company Contracts will include all loan agreements, agreements
under which the Company has imposed a Security Interest on any of its assets, tangible or intangible, equipment obligations, Tangible
Property leases and lease purchase agreements, Intellectual Property licenses, agreements or other arrangements imposing a non-competition
or non-solicitation obligation on the Company, agreements, understandings and arrangements involving the Company, agreements and understandings
with all material customers and suppliers of the Company (including, inter alia, agreements for the purchase or sale of raw materials,
commodities, supplies, products, or other personal property, or for the furnishing or receipt of services), any power of attorney given
by the Company, any agreement, instrument or deed pursuant to which a third party is entitled or authorized to bind or commit the Company
to any obligation, any agreements under which the Company has created, incurred, assumed or guaranteed any indebtedness for borrowed money,
agreements concerning a partnership or joint venture, any profit sharing, share option, share purchase, share appreciation, deferred compensation,
severance, or other material plan or arrangement for the benefit of its current or former directors, officers, and employees, any collective
bargaining agreement; any agreement for the employment of any individual on a full-time, part-time, consulting, or other basis, any agreement
under which the Company has advanced or loaned any amount to any of its directors, officers, and employees or their affiliates, any agreement
under which the consequences of a default or termination could have a material adverse effect on the business or financial condition,
of the Company, and any other instrument under which the Company may be required to make any payments.

 

    16

     

    

 

3.11.3.  

 

(a)  Each
Company Contract is a legal, valid and binding agreement of the Company, enforceable by or against the Company in accordance with its
terms, and in full force and effect, and the Company and Founders do not have any knowledge that any Company Contract is not a valid and
binding agreement of the other parties thereto. The Company Contracts will continue to be legal, valid, binding, enforceable, and in full
force and effect on identical terms following the consummation of the transactions contemplated hereby.

 

(b)  The
Company is in compliance in all material respects with the provisions of the Company Contracts, and the Company has no reason to believe
that it will not be able to fulfill fully and in a timely manner all of its obligations under the Company Contracts.

 

(c)  The
Company is not in breach of or default under any Company Contract, and no event has occurred which with the passage of time, the giving
of notice or otherwise would constitute such a breach or default, or would result in a loss of rights by the Company or in the creation
of any lien, charge, encumbrance or other third party right in or to any of the Company’s assets.

 

(d)  To
the best knowledge of the Company and Founders, there exists no breach or default of any of the Company Contracts by any other party thereto.
No party has repudiated any provision of any Company Contract.

 

(e)  The
Company is not restricted in any way, directly or indirectly, by any Company Contract from carrying on its business as presently conducted
and as proposed to be conducted.

 

3.12.  Insurance

 

3.12.1.  A
List of the insurance policies of the Company is included in Section 3.12.1 of the Schedule of Exceptions. The Company is covered
by insurance which is in scope and amount customary and reasonable for the business in which it is engaged and provides adequate insurance
coverage for the assets and the operations of the Company for all risks normally insured against an entity to carry on the same business
or businesses as the Company. Such policies are valid, outstanding and enforceable, and, to the Company’s and Founders’ reasonable belief
are issued by an insurer that is financially sound and reputable. The insurance policies are sufficient for compliance with all material
applicable legal requirements and agreements to which the Company is a party, or by which it is bound.

 

3.12.2.  The
Company has complied with all conditions of such insurance policies and has not done or suffered anything to be done, which has rendered
or might render any of the aforesaid policies of insurance void or void-able.

 

3.12.3.  There
is no claim outstanding or asserted under any of such insurance policies or that has been disallowed or improperly filed, nor are there,
to the Company’s and Founders’ best knowledge, any circumstances likely to give rise to any such claim. There are no claims outstanding
or asserted under any of such insurance policies. With respect to each insurance policy described herein, no party to the policy has repudiated
any provision thereof.

 

3.13.  Bank
Accounts. Section 3.13 of the Schedule of Exceptions sets forth a full and accurate details of all banks and financial institutions
in which the Company have an account, deposit, safe-deposit box, lock box or line of credit or other loan facility or relationship, including
the names of all persons authorized to draw on those accounts or deposits, or to borrow under such lines of credit or other loan facilities,
or to obtain access to such boxes. The Company is in full compliance with all its obligations with respect to, and it is not in violation
of or in breach under any terms and conditions applicable to, such financial institutions and facilities. There are no certificates of
deposit, debt or equity securities and other investments owned, beneficially or of record, by the Company.

 

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3.14.  Employees

 

3.14.1.  A
complete and accurate list of all employees, officers, directors and consultants of the Company and their general terms of employment
or engagement is included in Section 3.14.1 of the Schedule of Exceptions. All of the Company’s employees and consultants, who
are currently employed by or engaged with the Company, are parties to an employment agreement in the standard forms used by the Company.
Except as set forth in Section 3.14.1 of the Schedule of Exceptions, the Company does not have any employment or consulting contract
with any officer or employee or any other consultant or person which is not terminable by it at will without liability, upon no more than
ninety (90) days prior notice. Except as set forth in Section 3.14.1 of the Schedule of Exceptions, no key employee of the Company
has been dismissed in the last 12 months, or has given notice of termination of his/her employment.

 

3.14.2.  The
Company has complied with all laws and regulations applicable to its employees (and all the appropriate payments to the Tax authorities,
the Institute of National Insurance and any other relevant authority were made on their behalf, and all payments to such employees were
made in accordance therewith, including, inter alia, adequate payments for overtime, sick days and vacation days as well as convalescence
pay) and with all agreements, arrangements (collective or personal), promises and obligations relating thereto. There has not been and
there was not threatened any proceeding against or affecting the Company relating to the alleged violation of any applicable laws or agreements,
undertaking, promises or any other obligation pertaining to labor relations or employment matters. The Company has complied with all legal
and contractual requirements relating to employment, equal employment opportunity, nondiscrimination, immigration, wages, hours, vacations,
sick pay, severance pay, recuperation pay, benefits, collective bargaining, the payment of social security and similar Taxes and occupational
safety and health and made all necessary reserves relating to all such liabilities. The Company is not liable for the payment of any compensation,
damages, Taxes, fines, penalties, or other amounts, however designated, for failure to comply with any of the foregoing legal or contractual
requirements and all liabilities relating thereto are set forth in the Financial Statements.

 

3.14.3.  Except
for extension orders of common application to all employees in Israel, the Company is not a party or subject to any collective bargaining
agreement with any labor union or any local or subdivision thereof.

 

3.14.4.  Except
as set forth in Section 3.14.4 to the Schedule of Exceptions, the Company has no liabilities to existing or former employees or
consultants, other than their current one-month salary, including, inter alia, with respect to accrued vacation days sick days, all amounts
payable with respect to which has been paid in full by the Company or fully reserved for in its Financial Statements. Without derogating
from the generality of the above, the severance pay and accrued vacation days due to the Company’s employees is fully funded and the Company
is not aware of any circumstance whereby any employee might make any claim for compensation on termination of employment beyond the statutory
severance pay to which such employee is entitled.

 

3.14.5.
Each current or former employee, consultant and officer of the Company has executed valid and binding agreements with the Company regarding
confidentiality, ownership proprietary information, non-competition and non-solicitation. The Company is not aware that any of its current
or former employees, consultants or officers is in violation of any of the foregoing, and the Company has taken and continues to take
security measures to protect such information, which measures are reasonable and customary in the industry in which the Company operates.

 

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3.14.6.  Except
as set forth in Section 3.14.1 of the Schedule of Exceptions, to the Company’s and Founders’ best knowledge, each officer
(other than the Company’s directors) and key employee of the Company is currently devoting one hundred percent (100%) of his or
her business time to the conduct of the business of the Company.

 

3.15.  Governmental
Benefits. Section 3.15 to the Schedule of Exceptions includes a true and complete list and details of all grants, loans, tax
relief or other benefits received by the Company from the State of Israel or any agency thereof, or from any non-Israeli governmental
or administrative agency, or from any third party (collectively, “Grants and Benefits”). The Company is in compliance
with all respective provisions, terms and conditions applicable to such Grants and Benefits. Without derogating from the generality of
the foregoing, the Company has never been in violation of or in default under any provisions of the Chief Scientist’s Instrument
of Approval which has been issued to the Company during the period preceding to the date hereof, and has complied in all respects with
all terms and conditions thereof in connection with any all affairs of the Company, including, inter alia, the filing of all reports
and requests, and the application for and obtainment of all consents and approvals, required to be filed, applied for or obtained, as
applicable, under any of the foregoing or under any applicable law, statute, regulation or otherwise in connection with any transactions
consummated by the Company at any time prior to the date hereof.

 

3.16.  Compliance.
The Company is not in violation of or default under any provision of (i) any of its Corporate Documents, or (ii) any of the Company Contract,
or (iii) any law, instrument, statute, ordinance, regulation, order, writ, injunction, decree, or judgment of any court or any governmental
department, commission, board, bureau, agency or instrumentality, domestic or foreign, that applicable to the Company or to any of its
property, assets or business (a) under its Incorporation Documents. The Company has not received any notice from any administrative agency
or other governmental body claiming that the Company is in violation of or otherwise not in compliance with any of the above.

 

3.17.  Litigation.
Neither the Company or any of its assets, nor any of the Company’s officers, directors or employees (in their capacity as such),
is (i) subject to any outstanding injunction, judgment, order, decree, ruling, or charge, or (ii) a party or is to the best knowledge
of the Company and Founders is threatened to be made a party to any action, suit, proceeding, hearing, inquiry or investigation of, in
or before any court, arbitration board, tribunal or quasi-judicial or administrative or other governmental agency of any state, local,
or foreign jurisdiction. There is no action, suit, proceeding or investigation by the Company currently pending or that the Company intends
to initiate. For the avoidance of doubt, the foregoing includes, without limitation, actions, suits, proceedings or investigations, pending
or threatened, against the Company involving the prior employment of any of the employees of the Company or their obligations under any
agreements with prior employers.

 

3.18.  Interested
Party Transactions. No officer, director or stockholder of the Company and no Founder, or any affiliate or family member of any such
person or entity or the Company, has or has had, either directly or indirectly, (a) an interest in any person or entity which (i) furnishes
or sells services or products which are furnished or sold or are proposed to be furnished or sold by the Company, or (ii) purchases
from or sells or furnishes to the Company any goods or services, or (b) a beneficial interest in any contract or agreement to which
the Company is a party or, to the best knowledge of the Company and the Founders, by which it may be bound or affected. There are no existing
arrangements or proposed transactions between the Company and any officer, director, Founder, or holder of more than 1% of the share capital
of the Company, or any affiliate or associate of any such person. Except as set forth in Section 3.18 of the Disclosure Schedule,
no Founder, other employee, shareholder, officer, or director of the Company is indebted to the Company, nor is the Company indebted (or
committed to make loans or extend or guarantee credit) to any of them.

 

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3.19.  Brokers.
The Company has no contract, arrangement or understanding with any broker, finder or person acting in a similar capacity, with respect
to the transactions contemplated by this Agreement and no such person or entity is or will be entitled to any brokerage or finder fee
or any other commission or other similar fee, directly or indirectly, with respect to the transactions contemplated hereby. The Company
agrees to indemnify and hold the Investors harmless from and against any claim or liability resulting from any party claiming any such
commission or fee, if such claims shall be contrary to the foregoing statement.

 

3.20.  Licenses.
Section 3.20 to the Schedule of Exceptions contains a correct and complete list of all consents, permits, registrations or authorizations
(public and private) (collectively “Licenses”) used by the Company in the conduct of its business. The Licenses
constitute all Licenses as are necessary, to carry on the Company’s business or to exploit the Company’s assets (including
by way of sale, licensing or distribution of the Products) as conducted and as proposed to be conducted. All Licenses are valid and in
full force and effect and to the best knowledge of the Company and the Founders, there is no basis upon which the aforementioned could
be suspended, canceled or revoked. All Licenses shall continue to be in full force and effect as of and following the Initial Closing,
and shall not be affected in any way by the consummation of the transactions contemplated hereby.

 

3.21.  No
Powers of Attorney. There are no outstanding power of attorney executed on behalf of the Company. No person or entity, as agent or
otherwise, is entitled to or authorized to bind or commit the Company to any obligation and neither Company nor the Founder is aware of
any person or entity purporting to do so.

 

3.22.  Product
Warranty. The Company has not manufactured, sold, leased or delivered any Products.

 

3.23.  Obligations
to the Office of the Chief Scientist (the “OCS”). The Company is operating within the Incubator in accordance with
the incubator program administrated by the OCS pursuant to Directive 8.3 and is therefore, subject to OCS regulations and applicable laws.
The Company and the Founders have complied with all the terms and provisions of all grants received by the Company from the OCS and applicable
laws and regulations (including the provisions of Directive 8.3), and the Company continues to be eligible to receive the full funding
available to it in accordance with the application submitted by it for the receipt of such grants, and in accordance with the terms on
which such grants have been approved by the OCS.

 

3.24.  Environmental.
The Company has previously and is currently complying in all material respects with its obligations under all environmental laws to which
it is subject in connection with the operation of its business, its occupancy and use of facilities and otherwise. The Company has not
received any notice alleging any non-compliance with or potential liability pursuant to any environmental law or with respect to any materials
utilized in Products or in the conduct of its business. The Company has no liability or unfulfilled obligation, whether fixed, absolute,
contingent or otherwise, under any environmental law, including any liability, responsibility or obligation for fines or penalties, or
for investigation, expense, removal or remedial action to effect compliance with or discharge any duty, obligation or claims under any
such law, and neither the Company nor the Founders know of any basis for asserting such liability or obligation.

 

3.25.  Authorization
and Approvals; Validity; Third Party Consents

 

3.25.1.  The
Company has all requisite power and authority (corporate and other) to execute and deliver this Agreement, the Investors Rights Agreement
and all other agreements, certificates or other instruments ancillary hereto (collectively, the “Ancillary Agreements”),
to perform its obligations hereunder and thereunder and to consummate the transactions contemplated hereby.

 

    20

     

    

 

3.25.2.  All
corporate actions on the part of the Company necessary for the authorization, execution, delivery and performance of all its obligations
under this Agreement and the Ancillary Agreements, have been (or will be) taken prior to the Initial Closing.

 

3.25.3.  This
Agreement and all Ancillary Agreements will be at or prior to the Initial Closing duly and validly executed and delivered by the Company
and when executed and delivered by or on behalf of the Company, shall constitute the valid and legally binding obligations of the Company,
legally enforceable against the Company in accordance with their respective terms.

 

3.25.4.  Except
as set forth in Section 3.25 of the Disclosure Schedule the Company does not need to give any notice to, make any filing with, or obtain
any authorization, consent, or approval of any government, governmental agency or any third party in order to consummate the transactions
contemplated by this Agreement and the Ancillary Agreements. Except as set forth in Section 3.25 of the Disclosure Schedule, no consent,
approval, order, license, permit, action by, or authorization of or designation, declaration, registration or authorization of the action
by, or filing with, any person or entity, including any court, governmental or regulatory authority, commission, board, administrative
agency or non-governmental third party on the part of the Company is required in connection with the execution and delivery of this Agreement
and the Ancillary Agreements, the performance of the Company’s obligations hereunder and thereunder, or the consummation of the
transactions contemplated hereunder or thereunder, including, without limitation, the issuance and sale of the Purchased Shares to the
Investors or to the Milestone Investors, as applicable.

 

3.25.5.  The
execution, delivery and performance of this Agreement and of the Ancillary Agreements and the consummation of the transactions contemplated
hereby and thereby will not result in:

 

(a)  any
violation of, be in conflict with or constitute, with or without the passage of time or giving of notice, a default under, any provision
of the Incorporation Documents, or of any instrument, judgment, order, writ, decree, license, permit, statute, rule, regulation, constitution,
injunction, ruling, charge, or other restriction of any government, governmental agency, or court to which the Company is a party or by
which it or any of its property is bound;

 

(b)  a
conflict with, a breach of, constitution of a default under, acceleration of, creation in any party the right to accelerate, terminate,
modify, or cancel, or require any notice under any agreement, contract, lease, license, instrument, or other arrangement to which the
Company is a party or by which it is bound or to which any of its assets is subject (or result in the imposition of any Security Interest
upon any of its assets).

 

(c)  the
suspension, revocation, impairment, forfeiture, or non-renewal of any permit, license, authorization, or approval applicable to the Company,
its business or operations or any of its assets; or

 

(d)  discontinuation
of, or changes in the terms of, any business activity in which the Company is currently engaged with any third party.

 

3.25.6.  Other
than as obtained at or prior to the Initial Closing and presented to the Investors, no consent of any third party is required in connection
with the consummation by the Company of this Agreement and the transactions contemplated hereby, and without derogating from the generality
of the above, no consent, except as set forth in Section 3.25 of the Disclosure Schedule, approval, order or authorization of, or registration,
qualification, designation, declaration or filing with any governmental authority on the part of the Company is required in connection
with the valid execution and delivery of this Agreement and the consummation of any other transaction contemplated hereby.

 

    21

     

    

 

3.26.  Budget.
The Company’s preliminary budget and plan presented to the Investors, has been prepared in good faith and with reasonable professional
care by the Company. As of the date hereof, there are no other material facts or matters known to the Company or the Founders which may,
in their opinion, render the budget and plan untrue or misleading in any way.

 

3.27.  No
Public Offer. The Company has not violated any applicable securities laws or regulations. Neither the Company nor anyone acting on
its behalf has offered securities of the Company or any part thereof or any similar securities for issuance or sale to, or solicit any
offer to acquire any of the same from, anyone so as to make issuance and sale of the Purchased Shares issuable under this Agreement not
exempt from the registration requirements of Section 5 of the Securities Act of 1933, as amended (the “Securities Act”)
or the Israeli Securities Law, 1968. None of the shares of the Company’s capital stock issued and outstanding has been offered or sold
in such a manner as to make the issuance and sale of such shares not exempt from such registration requirements, and all such shares of
capital stock have been offered and sold in compliance with all applicable securities laws

 

3.28.  Disclosure.
The representations and warranties of the Company in this Agreement (including the Schedules and Exhibits attached hereto) or in any certificate
made or delivered in connection herewith are each accurate, correct and complete in all respects, and do not contain any untrue statement
of a material fact or omits to state a material fact necessary to make the statements herein or therein not false or misleading, in view
of the circumstances in which they were made. There is no material fact or information individually or in the aggregate relating to the
business, condition (financial or otherwise), affairs, operations, prospects, assets or properties of the Company, existing as of the
date hereof, that has not been expressly disclosed to the Investors by the Company and which is reasonably necessary to enable each Investor
to decide to enter into the transactions contemplated in this Agreement. The Investors have the right to rely fully upon the representations,
warranties, covenants and agreements of the Company contained in this Agreement (including, inter alia, any Schedule or Exhibit hereto)
or in any certificate made or delivered in connection herewith and the Company agrees to indemnify, defend and hold harmless such Investor
as further elaborated in Section 5.8 below.

 

3.29.  Effectiveness;
Survival. Each representation and warranty given in Section 3 of this Agreement is deemed to be made on the date of this Agreement
at the Initial Closing and, as applicable, at the Milestone Closing, and shall survive and remain in full force and effect for a period
of five (5) years after the Initial Closing, and the Company agrees to indemnify, defend and hold harmless such Investor as further elaborated
in Section 5.8 below.

 

		4.	Representations of the Investors

 

Each Investor hereby represents
and warrants, with respect to itself only, to the Company at the Initial Closing and, for the purpose of this Section 4 only, as of the
Milestone Closing, if and when occurs:

 

4.1.  Organization;
Approvals. Such Investor is duly organized, validly existing and in good standing under the laws of the jurisdiction in which it has
been incorporated, has all requisite power and authority to execute and deliver this Agreement and the agreement to be executed by such
Investor pursuant to this Agreement, and to consummate the transactions and perform its obligations contemplated hereby and thereby. This
Agreement and the agreements to be executed by such Investor under this Agreement, when executed and delivered by such Investor, will
be duly and validly authorized, executed and delivered by such Investor and shall constitute the valid and binding obligations of such
Investor, legally enforceable against such Investor in accordance with their respective terms, except as such obligations and enforceability
may be limited by applicable bankruptcy and other similar laws affecting the enforcement of creditors’ rights generally and except
that the availability of equitable remedies is subject to the discretion of the court before which any proceeding therefor may be brought
(whether in law or in equity). No consent, approval, order, license, permit, action by, or authorization of or designation, declaration,
or filing with any governmental authority on the part of such Investor is required that has not been, or will not have been, obtained
by such Investor prior to the Initial Closing in connection with the valid execution, delivery and performance of this Agreement and the
other agreements to be executed by such Investor pursuant to this Agreement or the consummation of the transactions contemplated hereby
or thereby.

 

    22

     

    

 

4.2.  Authorization;
No Breach. All corporate action on the part of such Investor, its partners/shareholders and directors necessary for the authorization,
the execution, delivery and performance of the obligations of such Investor under this Agreement and under the other agreements to be
executed by such Investor pursuant to this Agreement, and for the consummation by such Investor of the transactions contemplated hereby
and thereby, have been (or will be) taken prior to the Initial Closing. Neither the execution and delivery by such Investor of this Agreement
and the other agreements to be executed by such Investor pursuant to this Agreement nor compliance by such Investor with the terms and
provisions hereof or thereof, will conflict with, or result in a breach or violation of, any of the terms, conditions and provisions of:
(i) such Investor’s Certificate of Incorporation or Articles of Association as in effect on this date or other governing instruments
of such Investor, (ii) any judgment, order, injunction, decree, or ruling of any court or governmental authority, domestic or foreign,
(iii) any agreement, contract, lease, license or commitment to which such Investor is a party or to which it is subject, or (iv) applicable
law. Such execution, delivery and compliance will not require the consent or approval of any person or entity pursuant to any agreement,
contract or commitment referred to in this paragraph, which consent or approval has not heretofore been obtained.

 

4.3.  Brokers.
No agent, broker, investment banker, person or firm acting in a similar capacity on behalf of or under the authority of such Investor
is or will be entitled to any broker’s or finder’s fee or any other commission or similar fee, directly or indirectly, on account of any
action taken by such Investor in connection with any of the transactions contemplated under this Agreement. The Investors agree to indemnify
and hold the Company harmless from and against any claim or liability resulting from any party claiming any such commission or fee, if
such claims shall be contrary to the foregoing statement

 

4.4.  Access
to Data; Experience. Such Investor is an experienced investor, has had an opportunity to discuss to such Investor’s satisfaction
the Company’s business, management and financial affairs with the Company’s management. Such Investor represents and agrees
that the Purchased Shares and the Ordinary Shares issuable upon conversion of the Purchased Shares are purchased only for investment,
for his or its own account, and not with a view to, or for immediate resale in connection with, any distribution thereof. Such Investor
(a) has sufficient knowledge and experience in investing in companies similar to the Company in terms of the Company’s stage of
development so as to evaluate the risks and merits of its investment in the Company, it understands and acknowledges that the Company
has a limited financial and operating history and that an investment in the Company is highly speculative and involves substantial risks,
it can bear the economic risk of its investment in the Company and is able, without impairing such Investor’s financial condition,
to hold the Purchased Shares and the Ordinary Shares issuable upon conversion thereof for an indefinite period of time and to suffer a
complete loss of such Investor’s investment.

 

4.5.  Each
of the Investors is aware that the Company is operating within the Incubator in accordance with the incubator program administrated by
the OCS pursuant to Directive 8.3 and that the Company is subject to OCS regulations and applicable laws.

 

    23

     

    

 

5.
Certain Covenants

 

5.1.
Use of Proceeds. The Company shall utilize the proceeds of the issuance and sale of the Purchased Shares to further its
business goals in accordance with a budget (as approved by the Investors) as shall be approved by the Board following the Initial Closing
and as may be amended from time to time by the Board, all in compliance with the 2nd Amended Articles.

 

5.2.  Press
Releases. The Parties will coordinate in advance all announcements to the press or the general public concerning this Agreement and
otherwise regarding the Company.

 

5.3.  Expenses.
Each party hereto will bear its own fees and expenses in connection with the transactions contemplated hereby, whether or not such transactions
shall be consummated; provided, however, that subject to the consummation of the Initial Closing, at the Initial Closing, the Company
will pay to the Investors all reasonable legal and other fees, costs and expenses incurred in connection with the investment contemplated
hereby, including without limitation in connection with the legal due diligence process, negotiations and preparation of transaction documents,
in an amount not to exceed $35,000 plus VAT. In addition, whether or not such transactions shall be consummated, the Company shall hire
and pay all fees, costs and expenses incurred in connection with the IP due diligence process (including the freedom to operate analysis),
in an amount not to exceed $5,000 plus VAT

 

5.4.  Directors’
and Officers’ Liability Insurance Within 30 days of the Initial Closing, the Company will procure from financially sound and
reputable insurers, and in form and substance reasonably acceptable to the Investors, directors’ and officers’ liability insurance
providing for per-event/one year-period coverage of at least $3,000,000, for officers and directors of the Company, which insurance will
take effect retroactively from the date of the Initial Closing. The Company will maintain in full force and effect such directors’
and officers’ liability insurance, in the same form, substance and amount (and shall pay all premiums with respect thereto), unless
otherwise determined by the Investors.

 

5.5.  Key
Man Insurance. Following the Initial Closing, the Board shall discuss the Company’s need to adopt a key man insurance policy on the
life of each or any of the Founders.

 

5.6.  Proprietary
Information and Non-Competition Agreement. The Company will not employ, or continue to employ, and will ensure that any subsidiary
thereof will not employ or continue to employ, any person who will have access to confidential information with respect to the Company,
such subsidiary and their operations unless such person has executed an agreement substantially in the form of the Proprietary Information
and Competition Agreement to protect the confidential information.

 

5.7.  Interim
Period. During the period prior to the Initial Closing, the Company shall conduct its business solely in the ordinary course of business
and, among other things, shall not declare or make any distribution of any kind to shareholders nor enter into any transaction described
in Section 3.18 hereof. The Company and the Founders shall cooperate with the Investors in providing all due diligence material and other
related assistance to facilitate the Investors’ due diligence process

 

    24

     

    

 

		5.8	Indemnification

 

5.8.1  The
Company shall indemnify each Investor (including its directors, officers, employees and agents) against, and hold Investors harmless from,
damages, expenses, losses, costs, and/or liabilities (collectively, “Losses”) resulting from, or arising out of, or in
connection with, a breach of its representations, warranties or covenants made in this Agreement (including the exhibits and schedules
hereto), and all actions, suits, proceedings, judgments, costs and legal or other expenses (collectively, “Expenses”)
incident to any of the foregoing or the enforcement of the provisions hereof.

 

5.8.2  If
any claim, suit, action or other proceeding to which the indemnity set forth herein applies is brought against one or more of the Investors,
the Investors shall give the Company prompt notice of same, and the Company shall have the right to participate in, or assume the defense
of, such claim, suit, action or other proceeding, provided that the Investors cooperate in such defense. Investors may not adjust, settle
or compromise any claim, suit, action or other proceedings brought against them to which the indemnity set forth herein applies without
the prior consent of the Company.

 

5.8.3  Notwithstanding
the above, the Investors shall not be entitled to claim for indemnification after the lapse of five (5) years from the date of Initial
Closing.

 

		6.	Miscellaneous

 

6.1.  Further
Assurances. Each of the parties hereto shall perform such further acts and execute such further documents as may reasonably be necessary
to carry out and give full effect to the provisions of this Agreement and the intentions of the parties as reflected thereby.

 

6.2.Governing Law;
Jurisdiction. This Agreement shall be governed by and construed in accordance with the laws of the State of Israel, without regard
to any applicable principles of conflicts of laws. Any dispute arising under or in relation to this Agreement shall be resolved exclusively
in the competent court located in Israel, Tel Aviv, and each of the parties hereby irrevocably submits to the exclusive jurisdiction of
such court.

 

6.3.  Successors
and Assigns; Assignment. Except as otherwise expressly limited herein, the provisions hereof shall inure to the benefit of, and be
binding upon, the successors, assigns, heirs, executors, and administrators of the parties hereto. None of the rights, privileges, or
obligations set forth in, arising under, or created by this Agreement may be assigned or transferred without the prior consent in writing
of each party to this Agreement, with the exception of the following assignments and transfers which may be made freely without such consent
in a duly effected transfer of shares entitled or subject to such rights, privileges or obligations, and subject to the transferee providing
the Company with a confirmation in writing that it is bound by all terms and conditions of this Agreement as if it were an original party
to it: (a) assignments and transfers between Investors; (b) assignments and transfers from an Investor to any Permitted Transferee of
such Investor (as defined in the Amended Articles).

 

6.4.  Entire
Agreement; Amendment and Waiver. This Agreement and the Schedules and Exhibits hereto constitute the full and entire understanding
and agreement between the parties with regard to the subject matters hereof and thereof. Any term of this Agreement may be amended and
the observance of any term hereof may be waived (either prospectively or retroactively and either generally or in a particular instance)
only with the written consent of the Company, Vitalife (as defined in Schedule A) and Medica (as defined in Schedule A).

 

    25

     

    

 

6.5.  Notices,
etc. All notices and other communications required or permitted hereunder to be given to a party to this Agreement shall be in writing
and shall be sent via facsimile or email or mailed by registered or certified mail, postage prepaid, or prepaid air courier, or otherwise
delivered by hand or by messenger, addressed to such party’s address as set forth below:

 

 

	 	
    if to the Investors: 
	To the respective addresses set forth in Schedule A
	 	 	 
	 	With a copy to:	
    With respect to Medica to:

    Kantor & Co.

    Oz House

    12th Floor

    14 Abba Hillel Silver Road

    Ramat- Gan, 52506 Israel 

    Fax:+972-3-6133372

    Attn Rachel Cavallero Adv.

    e-mail rcavallero@kantor-law.com

     

    With respect to Vitalife to:

     

    Amit, Pollak, Matalon & Co.

    NITSBA Tower

    19th floor

    17 Yitzhak Sadeh Street

    Tel Aviv 67775, Israel

    Fax: +972-3-5689001

    Attention: Maya Issacharov, Adv.

    e-mail: m_issacharov@apm-law.com 

	 	 	 
	 	if to the Company	
    Regentis Biomaterials Ltd.

    Matam-Advanced Technology Center

    Building No. 30

    POB 15054

    Haifa 31905

    Fax: +972-4-854-6617

    Attn.: Yehiel Tal

    email: yehiel@regentis.co.il

 

    26

     

    

 

	 	
    if to the Founders:

     
	
    Dr. Dror Seliktar

    Bio-Medical Engineering Department

    Technion

    Technion City

    Haifa 32000, Israel

    Fax: + 972-___________

    email: dror@bm.technion.ac.il

     

    Yehiel Tal

    6 Hamaish Street

    Zichron Yaakov, Israel

    Fax: +972-____________

    email: yehiel@regentis.co.il 

	 	 	 
	 	if to the Incubator	
    The Technological Incubator Founded by the Technion
    R&D Foundation

    Matam-Advanced Technology Center

    Building No. 30

    POB 15054

    Haifa 31905

    Fax: +972-4-854-6644

    Attn.: Moshe Katzenelson

    email: _______________

	 	 	 
	 	With a copy to:	
    Goldsobel & Kirshen

    Matam-Advanced Technology Center

    Building No. 30

    POB 15006

    Haifa 31905, Israel

    Attn. Avi Goldsobel, Adv.

    email: avi@goldlaw.co.il

 

or such other address with respect
to a party as such party shall notify each other party in writing as above provided. Any notice sent in accordance with this Section 6.5
shall be effective (i) if mailed, seven (7) business days after mailing, (ii) if by air courier, two (2) business days after delivery
to the courier service, (iii) if sent by messenger, upon delivery, and (iv) if sent via facsimile or email, upon transmission and electronic
confirmation of receipt or (if transmitted and received on a non-business day) on the first business day following transmission and electronic
confirmation of receipt.

 

6.6.  Delays
or Omissions. No delay or omission to exercise any right, power, or remedy accruing to any party upon any breach or default under
this Agreement, shall be deemed a waiver of any other breach or default theretofore or thereafter occurring. Any waiver, permit, consent,
or approval of any kind or character on the part of any party of any breach or default under this Agreement, or any waiver on the part
of any party of any provisions or conditions of this Agreement, must be in writing and shall be effective only to the extent specifically
set forth in such writing. Except as expressly set forth herein, all remedies, either under this Agreement or by law or otherwise afforded
to any of the parties, shall be cumulative and not alternative.

 

6.7.  Severability.
If any provision of this Agreement is held by a court of competent jurisdiction to be unenforceable under applicable law, then such provision
shall be excluded from this Agreement and the remainder of this Agreement shall be interpreted as if such provision were so excluded and
shall be enforceable in accordance with its terms; provided, however, that in such event this Agreement shall be interpreted so as to
give effect, to the greatest extent consistent with and permitted by applicable law, to the meaning and intention of the excluded provision
as determined by such court of competent jurisdiction.

 

6.8.  Counterparts.
This Agreement may be executed in any number of facsimile or computer PDF format counterparts, each of which shall be deemed an original
and enforceable against the parties actually executing such counterpart, and all of which together shall constitute one and the same instrument.

 

[Signature Pages Immediately Follow]

 

    27

     

    

 

IN WITNESS WHEREOF, the parties
hereto have executed this Series B Preferred Share Purchase Agreement as of the date first above written.

 

	Company:	 
	 	 
	Regentis Biomaterials Ltd.	 
	 	 
	By:	                                                            	 
	 	(Name & Title of Signatory)	 

 

[Regentis Biomaterials Ltd../ Signature Page
to

Series B Preferred Share Purchase Agreement/
August 2, 2007]

 

    28

     

    

 

IN WITNESS WHEREOF, the parties
hereto have executed this Series B Preferred Share Purchase Agreement as of the date first above written.

 

	The Incubator:	 
	 	 
	The Technological Incubator Founded by the Technion R&D Foundation Ltd.	 
	 	 
	By:	                 	 
		(Name & Title of Signatory)	 

 

[Regentis Biomaterials Ltd./ Signature Page
to

Series B Preferred Share Purchase Agreement/
August 2, 2007]

 

    29

     

    

 

IN WITNESS WHEREOF, the parties
hereto have executed this Series B Preferred Share Purchase Agreement as of the date first above written.

 

	The Founders:	 
		 
	 	 
	Dr Dror Seliktar	 
	 	 
	 	 
	Mr. Yehiel Tal	 

 

[Regentis Biomaterials Ltd../ Signature Page
to

Series B Preferred Share Purchase Agreement/
August 2, 2007]

 

    30

     

    

IN WITNESS WHEREOF, the parties
hereto have executed this Series B Preferred Share Purchase Agreement as of the date first above written.

 

The Investors:

 

	Medica III Investments (International) L.P.	 	Medica III Investments (Israel) L.P.
	 	 	 
	By:	Medica III Management L.P.	 	By: 	Medica III Management L.P.
	 	its general partner	 	 	its general partner
	By:	Medica III Management Co.	 	By:	Medica III Management Co.
	 	its general partner	 	 	its general partner
	 	 	 	 	 
	By:	 	 	By:	 
	Name: 	Ehud Geller	 	Name: 	 Ehud Geller
	Title:	Director	 	Title:	Director
	 	 	 	 	 
	Medica III Investments (S.F.) L.P.	 	Medica III Investments (P.F.) L.P.
	 	 	 
	By: 	Medica III Management L.P.	 	By:	Medica III Management L.P.
	 	its general partner	 	 	its general partner
	By: 	Medica III Management Co.	 	By: 	Medica III Management Co.
	 	its general partner	 	 	its general partner
	 	 	 
	By:	 	 	By:	 
	Name:	Ehud Geller	 	Name:	Ehud Geller
	Title:	Director	 	Title:	Director
	 	 	 
	Medica III Investments (Israel) (B) L.P.	 	Poalim Medica III Investments L.P. 
	 	 	 
	By: 	Medica III Management L.P.	 	By:	Medica III Management L.P.
	 	its general partner	 	 	its general partner
	 	 	 
	By: 	Medica III Management Co.	 	By: 	Medica III Management Co.
	 	its general partner	 	 	its general partner
	 	 	 
	By:	 	 	By:	 
	Name:	Ehud Geller	 	Name:	Ehud Geller
	Title:	Director	 	Title:	Director
	 	 	 

 

[Regentis Biomaterials Ltd../ Signature Page
to

Series B Preferred Share Purchase Agreement/
August 2, 2007]

 

    31

     

    

 

IN WITNESS WHEREOF, the parties
hereto have executed this Series B Preferred Share Purchase Agreement as of the date first above written.

 

The Investors:

 

	Vitalife Partners (Israel) L.P.	 	Vitalife Partners (DCM) L.P.
	 	 	 
	By:	Vitalife Partners Management L.P.,	 	By:	Vitalife Partners Management L.P.,
	 	its General Partner	 	 	its General Partner
	By:	Vitalife Life Sciences Ltd.,	 	By:	Vitalife Life Sciences Ltd.,
		its General Partner	 		its General Partner
	By:	 	 	By:	 
	Name:  	 	 	Name: 	 
	Title:		 	Title:	
	 	 	 
	Vitalife Partners (Overseas) L.P	 	SCP Vitalife Partners II, L.P.
	 	 	 
	By:	Vitalife Partners Management L.P.,	 	By:	SCP Vitalife II Associates, L.P.,
	 	its General Partner	 	 	its General Partner
	By:	Vitalife Life Sciences Ltd.,	 	By:	SCP Vitalife II GP, Ltd.,
		its General Partner	 	 	its General Partner
	By:	 	 	By:	
	Name:		 	Name:	
	Title:	 	 	Title:	 
	 	 	 
	SCP Vitalife Partners (Israel) II, L.P.	 	 
	 	 	 
	By:	SCP Vitalife II Associates, L.P.,	 	 
	 	its General Partner	 	 
	By:	CP Vitalife II GP, Ltd.,	 	 
	 	its General Partner	 	 
	By:	 	 	 
	Name:	 	 	 
	Title:	 	 	 

 

[Regentis Biomaterials Ltd../ Signature Page
to

Series B Preferred Share Purchase Agreement/
August 2, 2007]

 

    32

     

    

 

IN WITNESS WHEREOF, the parties
hereto have executed this Series B Preferred Share Purchase Agreement as of the date first above written.

 

	Technion Research and Development Foundation Ltd.
	 	 	 
	By:	          	 
	Name:	 	 
	Title:	 	 

 

[Regentis Biomaterials Ltd../ Signature Page
to

Series B Preferred Share Purchase Agreement/
August 2, 2007]

 

    33

     

    

 

SCHEDULE A

 

INVESTORS

 

Medica III Investments (International) L.P.

Medica III Investments (Israel) L.P.

Medica III Investments (S.F.) L.P.

Medica III Investments (P.F.) L.P.

Medica III Investments (Israel) (B) L.P.

Poalim Medica III Investments L.P.

(collectively: “Medica”)

 

Address:

 

11 Hamanofim Street

POB 2206

Herzelya Pituach 46725

Israel

 

Vitalife Partners (Israel) L.P.

Vitalife Partners (DCM) L.P.

Vitalife Partners (Overseas) L.P.

SCP Vitalife Partners II, LP

SCP Vitalife Partners (Israel) II, LP

(collectively “Vitalife”)

 

Address:

 

32B Habarzel Street

Tel Aviv 69710

Israel

 

Technion Research and Development Foundation Ltd.

 

Address:

 

Technion City

Haifa 32000

Israel

 

    34

     

    

 

SCHEDULE B

 

LENDING PURCHASERS AND BRIDGE LOANS

 

	Lending Purchasers	 	Principal	 	 	Interest	 
	 	 	 	 	 	 	 
	Vitalife Partners (Israel) L.P.	 	US$	49,686	 	 	US$	2,149.86	 
	 	 	 	 	 	 	 	 	 
	Vitalife Partners (DCM) L.P.	 	US$	50,188	 	 	US$	2,171.58	 
	 	 	 	 	 	 	 	 	 
	Vitalife Partners (Overseas) L.P.	 	US$	150,126	 	 	US$	6,511.14	 
	 	 	 	 	 	 	 	 	 
	Technion Research and Development Foundation Ltd.	 	US$	48,000	 	 	US$	2,074.18	 
	 	 	 	 	 	 	 	 	 
	Total	 	US$	298,000	 	 	US$	12,906.76	 

 

    35

     

    

 

SCHEDULE C

INVESTMENTS

 

ATTACHED

 

 

 

 

 

 

 

    36

     

    

 

SCHEDULE 1.2.1

 

The Milestone

 

The successful achievement by the Company of all
of (i) obtaining device designation in Europe and in the United States for the cartilage repair product and (ii) receiving regulatory
approval to commence cartilage repair clinical trials in Europe.

 

 

37

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