Document:

INDENTURE DATED AS OF MAY 10, 2004

 Exhibit 4.1 

  
 OSCIENT PHARMACEUTICALS CORPORATION 
  
 as Issuer 
  
 and 
  
 U.S. BANK NATIONAL ASSOCIATION 
  
 as Trustee 
  

  
 INDENTURE 
  
 Dated as of May 10, 2004 
  

  
 31⁄2% Senior Convertible
Notes Due 2011 
  

 TABLE OF CONTENTS 
  

					
	 	    	 	  	Page

	 RECITALS OF THE COMPANY
	  	1
		
	 ARTICLE 1 Definitions and Other Provisions of General Application
	  	1
	 Section 1.01.
	    	Definitions	  	1
	 Section 1.02.
	    	Compliance Certificates and Opinions	  	10
	 Section 1.03.
	    	Form of Documents Delivered to Trustee	  	11
	 Section 1.04.
	    	Acts of Holders; Record Dates	  	11
	 Section 1.05.
	    	Notices, Etc.	  	12
	 Section 1.06.
	    	Notice to Holders; Waiver	  	12
	 Section 1.07.
	    	Conflict with Trust Indenture Act	  	13
	 Section 1.08.
	    	Effect of Headings and Table of Contents	  	13
	 Section 1.09.
	    	Successors and Assigns	  	13
	 Section 1.10.
	    	Severability Clause	  	13
	 Section 1.11.
	    	Benefits of Indenture	  	13
	 Section 1.12.
	    	Governing Law	  	13
	 Section 1.13.
	    	Legal Holiday	  	14
		
	 ARTICLE 2 Security Forms
	  	14
	 Section 2.01.
	    	Forms Generally	  	14
	 Section 2.02.
	    	Form of Face of Security	  	14
	 Section 2.03.
	    	Form of Reverse of Security	  	14
	 Section 2.04.
	    	Form of Trustee’s Certificate of Authentication	  	14
	 Section 2.05.
	    	Legend on Restricted Securities	  	14
		
	 ARTICLE 3 The Securities
	  	15
	 Section 3.01.
	    	Title and Terms	  	15
	 Section 3.02.
	    	Denominations	  	15
	 Section 3.03.
	    	Execution, Authentication, Delivery and Dating	  	15
	 Section 3.04.
	    	Temporary Securities	  	16
	 Section 3.05.
	    	Registration; Registration of Transfer and Exchange; Restrictions on Transfer	  	16
	 Section 3.06.
	    	Mutilated, Destroyed, Lost and Stolen Securities	  	18
	 Section 3.07.
	    	Persons Deemed Owners	  	19
	 Section 3.08.
	    	Book-Entry Provisions for Global Securities	  	19
	 Section 3.09.
	    	Cancellation and Transfer Provisions	  	21
	 Section 3.10.
	    	CUSIP Numbers	  	22
		
	 ARTICLE 4 Satisfaction And Discharge
	  	23
	 Section 4.01.
	    	Satisfaction and Discharge of Indenture	  	23
	 Section 4.02.
	    	Application of Trust Money	  	23

  

					
	 ARTICLE 5 Remedies
	  	24
	 Section 5.01.
	    	Events of Default	  	24
	 Section 5.02.
	    	Acceleration of Maturity; Rescission and Annulment	  	25
	 Section 5.03.
	    	Collection of Indebtedness and Suits for Enforcement by Trustee	  	26
	 Section 5.04.
	    	Trustee May File Proofs of Claim	  	27
	 Section 5.05.
	    	Application of Money Collected	  	27
	 Section 5.06.
	    	Limitation on Suits	  	28
	 Section 5.07.
	    	Unconditional Right of Holders to Receive Payment	  	28
	 Section 5.08.
	    	Restoration of Rights and Remedies	  	29
	 Section 5.09.
	    	Rights and Remedies Cumulative	  	29
	 Section 5.10.
	    	Delay or Omission Not Waiver	  	29
	 Section 5.11.
	    	Control by Holders	  	29
	 Section 5.12.
	    	Waiver of Past Defaults	  	29
	 Section 5.13.
	    	Undertaking for Costs	  	30
	 Section 5.14.
	    	Waiver of Stay or Extension Laws	  	30
		
	 ARTICLE 6 The Trustee
	  	30
	 Section 6.01.
	    	Certain Duties and Responsibilities	  	30
	 Section 6.02.
	    	Notice of Defaults	  	31
	 Section 6.03.
	    	Certain Rights Of Trustee	  	31
	 Section 6.04.
	    	Not Responsible for Recitals	  	32
	 Section 6.05.
	    	May Hold Securities	  	32
	 Section 6.06.
	    	Money Held in Trust	  	32
	 Section 6.07.
	    	Compensation and Reimbursement	  	33
	 Section 6.08.
	    	Disqualification; Conflicting Interests	  	33
	 Section 6.09.
	    	Corporate Trustee Required; Eligibility	  	34
	 Section 6.10.
	    	Resignation and Removal; Appointment of Successor	  	34
	 Section 6.11.
	    	Acceptance of Appointment by Successor	  	35
	 Section 6.12.
	    	Merger, Conversion, Consolidation or Succession to Business	  	35
	 Section 6.13.
	    	Preferential Collection of Claims Against	  	36
		
	 ARTICLE 7 Holders’ Lists And Reports By Trustee
	  	36
	 Section 7.01.
	    	Company to Furnish Trustee Names and Addresses of Holders	  	36
	 Section 7.02.
	    	Preservation of Information; Communications to Holders	  	36
	 Section 7.03.
	    	Reports By Trustee	  	37
	 Section 7.04.
	    	Reports by Company	  	37
		
	 ARTICLE 8 Consolidation, Merger, Conveyance, Transfer Or Lease
	  	37
	 Section 8.01.
	    	Company May Consolidate, etc., Only on Certain Terms	  	37
	 Section 8.02.
	    	Successor Substituted	  	38
		
	 ARTICLE 9 Supplemental Indentures
	  	38
	 Section 9.01.
	    	Supplemental Indentures Without Consent of Holders	  	38
	 Section 9.02.
	    	Supplemental Indentures With Consent of Holders	  	39

  

 ii 

					
	 Section 9.03.
	    	Execution of Supplemental Indentures	  	41
	 Section 9.04.
	    	Effect of Supplemental Indentures	  	41
	 Section 9.05.
	    	Conformity with Trust Indenture Act	  	41
	 Section 9.06.
	    	Reference in Securities to Supplemental Indentures	  	41
		
	 ARTICLE 10 Covenants
	  	41
	 Section 10.01.
	    	Payments	  	42
	 Section 10.02.
	    	Maintenance of Office or Agency	  	42
	 Section 10.03.
	    	Money for Security Payments to be Held in Trust	  	42
	 Section 10.04.
	    	Statement by Officers as to Default	  	43
	 Section 10.05.
	    	Existence	  	44
	 Section 10.06.
	    	Reports and Delivery of Certain Information	  	44
	 Section 10.07.
	    	Resale of Certain Securities	  	44
	 Section 10.08.
	    	Book-Entry System	  	45
	 Section 10.09.
	    	Liquidated Damages Under the Registration Rights Agreement	  	45
	 Section 10.10.
	    	Information for IRS Filings	  	45
		
	 ARTICLE 11 Redemption And Repurchase Upon A Fundamental Change
	  	45
	 Section 11.01.
	    	Right to Redeem; Notices to Trustee	  	45
	 Section 11.02.
	    	Selection of Securities to be Redeemed	  	45
	 Section 11.03.
	    	Notice of Redemption	  	46
	 Section 11.04.
	    	Effect of Notice of Redemption	  	47
	 Section 11.05.
	    	Deposit of Redemption Price	  	47
	 Section 11.06.
	    	Securities Redeemed in Part	  	47
	 Section 11.07.
	    	Conversion Arrangement on Call for Redemption	  	47
	 Section 11.08.
	    	Repurchase of Securities at Option of the Holder Upon Fundamental Change	  	48
	 Section 11.09.
	    	Effect of Fundamental Change Repurchase Notice	  	54
	 Section 11.10.
	    	Deposit of Fundamental Change Repurchase Price	  	55
	 Section 11.11.
	    	Securities Repurchased in Whole or in Part	  	56
	 Section 11.12.
	    	Covenant to Comply With Securities Laws Upon Repurchase of Securities	  	56
	 Section 11.13.
	    	Repayment to the Company	  	56
		
	 ARTICLE 12 Interest Payments on the Securities
	  	56
	 Section 12.01.
	    	Interest Rate	  	56
		
	 ARTICLE 13 Conversion
	  	57
	 Section 13.01.
	    	Conversion Privilege	  	57
	 Section 13.02.
	    	Conversion Procedure	  	58
	 Section 13.03.
	    	Fractional Shares	  	59
	 Section 13.04.
	    	Taxes on Conversion	  	59
	 Section 13.05.
	    	Company to Provide Stock	  	59
	 Section 13.06.
	    	Adjustment of Conversion Rate	  	60

  

 iii 

					
	 Section 13.07.
	    	No Adjustment	  	65
	 Section 13.08.
	    	Adjustment for Tax Purposes	  	65
	 Section 13.09.
	    	Notice of Conversion Rate Adjustment	  	65
	 Section 13.10.
	    	Notice of Certain Transactions	  	65
	 Section 13.11.
	    	Effect of Reclassification, Consolidation, Merger or Sale on Conversion Privilege	  	66
	 Section 13.12.
	    	Trustee’s Disclaimer	  	67
	 Section 13.13.
	    	Voluntary Increase	  	67
	 Section 13.14.
	    	Company Determination Final	  	67
		
	 ARTICLE 14 Collateral Security
	  	68
	 Section 14.01.
	    	Collateral Security	  	68

  

					
	 EXHIBITS:
	  	 	  	 
			
	 Exhibit A
	  	Form of Face of Security	  	 
	 Exhibit B
	  	Form of Reverse of Security	  	 
	 Exhibit C
	  	Form of Trustee’s Certificate of Authentication	  	 
	 Exhibit D
	  	Fundamental Change Repurchase Notice	  	 

  

 iv 

 INDENTURE, dated as of May 10, 2004, between Oscient Pharmaceuticals Corporation, a corporation duly
organized and existing under the laws of the Commonwealth of Massachusetts, as Issuer (the “Company”), having its principal office at 100 Beaver Street, Waltham, MA 02453 and U.S. Bank National Association, a national banking
association, as Trustee (the “Trustee”). 
  
 RECITALS OF THE COMPANY 
  
 The Company has duly
authorized the creation of an issue of its 31⁄2% Senior Convertible Notes Due 2011 (each a “Security” and collectively, the “Securities”) of substantially the tenor and amount hereinafter set forth, and to
provide therefor the Company has duly authorized the execution and delivery of this Indenture. 
  
 All things necessary to make the Securities, when executed by the Company and authenticated and delivered hereunder and duly issued by the Company, the valid and legally binding obligations of the Company, and to make
this Indenture a valid and legally binding agreement of the Company, in accordance with the terms of the Securities and the Indenture, have been done. Further, all things necessary to duly authorize the issuance of the Common Stock of the Company
issuable upon the conversion of the Securities, and to duly reserve for issuance the number of shares of Common Stock issuable upon such conversion, have been done. 
  
 The Securities will be partially secured pursuant to the terms of the Pledge Agreement (as defined herein) by Pledged
Securities (as defined herein). 
  
 NOW, THEREFORE, THIS INDENTURE
WITNESSETH: 
  
 For and in consideration of the premises and the
purchases of the Securities by the Holders thereof, it is mutually agreed, for the benefit of the Company and the equal and proportionate benefit of all Holders of the Securities, as follows: 
  
 ARTICLE 1 
 Definitions and Other Provisions of General Application 
  
 Section 1.01. Definitions. For all purposes of this Indenture, except as otherwise expressly provided or unless the context otherwise requires:

  
 (i) the terms defined in this Article have
the meanings assigned to them in this Article and include the plural as well as the singular; 
  
 (ii) all other terms used herein and not otherwise defined that are defined in the Trust Indenture Act, either directly or by reference
therein, have the meanings assigned to them therein; 
  

 (iii) all accounting terms not otherwise defined herein have the meanings assigned to
them in accordance with GAAP; and 
  
 (iv) the
words “herein,” “hereof’ and “hereunder” and other words of similar import refer to this Indenture as a whole and not to any particular Article, Section or other subdivision. 
  
 “Act,” when used with respect to any Holder, has the meaning
specified in Section 1.04. 
  
 “Affiliate” of any
specified Person means any other Person directly or indirectly controlling or controlled by or under direct or indirect common control with such specified Person. For the purposes of this definition, “control” when used with respect to any
specified Person means the power to direct the management and policies of such Person, directly or indirectly, whether through the ownership of voting securities, by contract or otherwise; and the terms “controlling” and
“controlled” have meanings correlative to the foregoing. 
  
 “Agent Members” has the meaning specified in Section 3.08. 
  
 “Bid Solicitation Agent” means an independent nationally recognized securities dealer selected by the Company to solicit market bid quotations for the Securities, which initially shall be the Trustee
and in no event shall it be an Affiliate of the Company. 
  
 “Board of Directors” means, with respect to any Person, either the board of directors of such Person or any duly authorized committee of that board. 
  
 “Board Resolution” means, with respect to any Person, a copy of a resolution certified by the Secretary or
an Assistant Secretary of such Person to have been duly adopted by the Board of Directors and to be in full force and effect on the date of such certification, and delivered to the Trustee. 
  
 “Business Day” means any day other than a Saturday, a Sunday
or a day on which banking institutions in The City of New York or the city in which the Corporate Trust Office is located are authorized or obligated by law, or executive order or governmental decree to be closed. 
  
 “Capital Stock” means any and all shares, interests,
participations, rights or other equivalents (however designated) of corporate stock, including, without limitation, with respect to partnerships, partnership interests (whether general or limited) and any other interest or participation that confers
on a Person the right to receive a share of the profits and losses of, or distributions of assets of, such partnership. 
  
 “Cash Buy-Out” has the meaning specified in Section 11.08. 
  
 “Change of Control Event” means any transaction or event (whether by means of an exchange offer,
liquidation, tender offer, consolidation, merger, combination, reclassification, 

  

 2 

 
recapitalization or sale of all or substantially all of the Company’s assets or otherwise) in connection with which all or substantially all of the
Common Stock is exchanged for, converted into, acquired for or constitutes solely the right to receive, consideration which is not all or substantially all common stock or American Depositary Shares that (i) is listed on, or immediately after the
transaction or event will be listed on, a United States national securities exchange, or (ii) is approved, or immediately after the transaction or event will be approved, for quotation on the Nasdaq National Market or any similar United States
system of automated dissemination of quotations of securities prices. 
  
 “Closing Price” with respect to the Company’s Common Stock on any date means the closing price on such date as reported on the National Association of Securities Dealers Automated Quotation System or the principal U.S.
securities exchange on which the Company’s Common Stock is then listed, or, if the Company’s Common Stock is not quoted on the National Association of Securities Dealers Automated Quotation System and is not listed on a U.S. national or
regional exchange or, as reported on the principal other market on which the Company’s Common Stock is then traded. In the absence of such quotations, the Board of Directors of the Company will make a good faith determination of the closing
price. 
  
 “Commission” means the Securities and
Exchange Commission, as from time to time constituted, created under the Exchange Act, or, if at any time after the execution of this instrument such Commission is not existing and performing the duties now assigned to it under the Trust Indenture
Act, then the body performing such duties at such time. 
  
 “Common Stock” means the shares of Common Stock, par value $0.10 per share, of the Company as it exists on the date of this Indenture or any other shares of Capital Stock of the Company into which the Common Stock shall be
reclassified or changed or, in the event of a merger, consolidation or other similar transaction involving the Company that is otherwise permitted hereunder in which the Company is not the surviving corporation, the common stock, common equity
interests, ordinary shares or depositary shares or other certificates representing common equity interests of such surviving corporation or its direct or indirect parent corporation. 
  
 “Company” means the Person named as the “Company” in the first paragraph of this
instrument until a successor Person shall have become such pursuant to the applicable provisions of this Indenture, and thereafter “Company” shall mean such successor Person. 
  
 “Company Request” or “Company Order” means
a written request or order signed in the name of the Company by its Chairman of the Board, its Vice Chairman of the Board, its President or any Vice President, and by its Chief Financial Officer, its Treasurer, an Assistant Treasurer, its Secretary
or an Assistant Secretary, and delivered to the Trustee. 
  
 “Conversion Agent” means the Trustee or such other office or agency designated by the Company with notice provided to the Holders where Securities may be presented for conversion. 
  
 “Conversion Date” has the meaning specified in Section
13.02(a). 
  

 3 

 “Conversion Price” has the meaning specified in Section 13.01(c). 
  
 “Conversion Rate” has the meaning specified in Section
13.01(c). 
  
 “Corporate Trust Office” means the
office of the Trustee at which the corporate trust business of the Trustee shall, at any particular time, be principally administered, which office is, at the date of this Indenture, located at One Federal Street, 3rd Floor, Boston, Massachusetts 02110. 
  

“Corporation” means a corporation, association, company, joint-stock company or business trust. 
  
 “Current Market Price” has the meaning specified in Section
13.06(f). 
  
 “Default” means any event that is
or with the passage of time or the giving of notice or both would become an Event of Default. 
  
 “Determination Date” has the meaning specified in Section 13.06(d). 
  
 “Depositary” means The Depository Trust Company until a successor Depositary shall have become such pursuant to the applicable provisions
of this Indenture, and thereafter “Depositary” shall mean such successor Depositary. 
  
 “Event of Default” has the meaning specified in Section 5.01. 
  
 “Exchange Act” means the U.S. Securities Exchange Act of 1934, as amended. 
  
 “Expiration Date” has the meaning specified in Section 13.06(e). 
  
 “Expiration Time” has the meaning specified in Section
13.06(e). 
  
 “Fundamental Change” means any
transaction or event resulting in either a Change of Control Event or a Termination of Trading. 
  
 “Fundamental Change Company Notice” has the meaning specified in Section 11.08. 
  
 “Fundamental Change Repurchase Date” has the meaning
specified in Section 11.08. 
  
 “Fundamental Change
Repurchase Notice” has the meaning specified in Section 11.08. 
  
 “Fundamental Change Repurchase Price” has the meaning specified in the Securities. 
  
 “GAAP” means generally accepted accounting principles set forth in the opinions and pronouncements of the Accounting Principles Board of
the American Institute of Certified Public Accountants and statements and pronouncements of the Financial Accounting Standards Board 

  

 4 

 
or in such other statements by such other entity as have been approved by a significant segment of the accounting profession, in each case, as in effect in
the United States on the date hereof. 
  
 “Global
Security” means a Security in global form registered in the Security Register in the name of a Depositary or a nominee thereof. 
  
 “Government Obligations” means (A) securities that are (i) direct obligations of the United States of America, for the payment of which
the full faith and credit of the United States is pledged or (ii) obligations of a Person controlled or supervised by or acting as an agency or instrumentality of the United States, the payment of which is unconditionally guaranteed as a full faith
and credit obligation by the United States, which, in either case, are not callable or redeemable at the option of the issuer thereof at any time prior to the stated maturity thereof, or (B) any mutual fund that has at least 95% of its assets
continuously invested in investments of the type described in clause (A) above and has the highest rating attainable by Moody’s Investor Services and Standard & Poor’s Ratings Services, and shall also include a depository receipt
issued by a bank or trust company as custodian with respect to any such Government Obligation or a specific payment of interest on or principal of any such Government Obligation held by such custodian for the account of the holder of a depository
receipt; provided that (except as required by law) such custodian is not authorized to make any deduction from the amount payable to the holder of such depository receipt from any amount received by the custodian in respect of the Government
Obligation for the specific payment of interest on or principal of the Government Obligation evidenced by such depository receipt. 
  
 “Holder” or “Securityholder” means a Person in whose name a Security is registered in the Security Register. 

 
 “Indenture” means this instrument as originally executed
or as it may from time to time be supplemented or amended by one or more indentures supplemental hereto entered into pursuant to the applicable provisions hereof, including, for all purposes of this instrument and any such supplemental indenture,
the provisions of the Trust Indenture Act that are deemed to be a part of and govern this instrument and any such supplemental indenture, respectively. 
  
 “Initial Purchasers” means J.P. Morgan Securities Inc. and Merrill Lynch, Pierce, Fenner & Smith Incorporated. 
  
 “Interest Payment Date” means April 15 and October 15 of
each year, commencing October 15, 2004. 
  
 “Investment
Company Act” means the Investment Company Act of 1940 and any statute successor thereto, in each case as amended from time to time. 
  
 “Issue Date” means the date the Securities are originally issued as set forth on the face of the Security under this Indenture.

  

 5 

 “Liquidated Damages” shall mean the Liquidated Damages as defined in the Registration
Rights Agreement. 
  
 “Make-Whole
Premium” has the meaning specified in Section 11.08. 
  
 “Maturity,” when used with respect to any Security, means the date on which the principal, Repurchase Price or Fundamental Change of such Security becomes due and payable as therein or herein provided, whether at the
Stated Maturity, on a Redemption Date or Fundamental Change Repurchase Date, or by declaration of acceleration or otherwise. 
  
 “Notice of Conversion” has the meaning specified in Section 13.02. 
  
 “Notice of Default” has the meaning specified in Section 5.01. 
  
 “Officers’ Certificate” means a certificate
signed by the Chairman of the Board, the President or any Vice President, and by the Treasurer, an Assistant Treasurer, the Secretary or an Assistant Secretary, of the Company, and delivered to the Trustee. One of the officers signing an
Officers’ Certificate given pursuant to Section 10.04 shall be the principal executive, financial or accounting officer of the Company. 
  
 “Opinion of Counsel” means a written opinion of counsel, who may be external or in-house counsel for the Company. 
  
 “Outstanding,” when used with respect to Securities, means,
as of the date of determination, all Securities theretofore authenticated and delivered under this Indenture, except: 
  
 (i) Securities theretofore cancelled by the Trustee or delivered to the Trustee for cancellation; 
  
 (ii) Securities, or portions thereof, for whose payment or
redemption money in the necessary amount has been theretofore deposited with the Trustee or any Paying Agent (other than the Company) in trust or set aside and segregated in trust by the Company (if the Company shall act as its own Paying Agent) for
the Holders of such Securities; provided that if such Securities are to be redeemed prior to the maturity thereof, notice of such redemption shall have been given to the Holders as herein provided, or provision satisfactory to a Responsible Officer
of the Trustee shall have been made for giving such notice; and 
  
 (iii) Securities that have been paid or in exchange for or in lieu of which other Securities have been authenticated and delivered pursuant to this Indenture; 
  
 provided, however, that, in determining whether the Holders of the requisite Principal Amount
of the Outstanding Securities have given any request, demand, authorization, direction, notice, 

  

 6 

 
consent or waiver hereunder, Securities owned by the Company or any other obligor upon the Securities or any Affiliate of the Company or of such other
obligor shall be disregarded and deemed not to be Outstanding, except that, in determining whether the Trustee shall be protected in relying upon any such request, demand, authorization, direction, notice, consent or waiver, only Securities which a
Responsible Officer of the Trustee actually knows to be so owned shall be so disregarded. Securities so owned which have been pledged in good faith may be regarded as Outstanding if the pledgee establishes to the satisfaction of the Trustee the
pledgee’s right so to act with respect to such Securities and that the pledgee is not the Company or any other obligor upon the Securities or any Affiliate of the Company or of such other obligor. 
  
 “Paying Agent” means any Person (including the Company)
authorized by the Company to pay the principal of, interest and Liquidated Damages on the Redemption Price or Fundamental Change Repurchase Price of, any Securities on behalf of the Company. The Trustee shall initially be the Paying Agent.

  
 “Person” means any individual, corporation,
partnership, limited liability company, joint venture, trust, unincorporated organization or government or any agency or political subdivision thereof. 
  
 “Physical Securities” means permanent certificated Securities in registered form issued in denomination of $1,000 Principal Amount and
integral multiples thereof. 
  
 “Pledge Account”
means an account established by the Pledged Securities Intermediary pursuant to the terms of the Pledge Agreement for the deposit of the Pledged Securities purchased by the Company. 
  
 “Pledge Agreement” means the Pledge Agreement, dated as of the date hereof, by and among the Company, the
Trustee and the Pledged Securities Intermediary, as such agreement may be amended, restated, supplemented or otherwise modified from time to time. 
  
 “Pledged Securities” means the Government Obligations to be purchased by the Company and held in the Pledged Account in accordance with
the Pledge Agreement. 
  
 “Pledged Securities
Intermediary” means, initially, U.S. Bank National Association, as securities intermediary under the Pledge Agreement. 
  
 “Principal Amount” of a Security means the Principal Amount as set forth on the face of the Security. 
  
 “Purchase Agreement” means the Purchase Agreement, dated as
of May 4, 2004, entered into by the Company and the Initial Purchasers in connection with the sale of the Securities. 
  
 “Purchased Shares” has the meaning specified in Section 13.06(e). 
  

 7 

 “Qualified Institutional Buyer” or “QIB” shall have the meaning
specified in Rule 144A. 
  
 “Record Date” for the
interest payable on any Interest Payment Date means each April 1 and October 1 (whether or not a Business Day) next preceding such Interest Payment Date. 
  
 “Redemption Date” shall mean the date specified for redemption of the Securities in accordance with the terms of the Securities and
Article 11 hereof. 
  
 “Redemption Price” has the
meaning specified in the Securities. 
  
 “Registration
Rights Agreement” means the Registration Rights Agreement, dated as of May 10, 2004, between the Company and the Initial Purchasers, for the benefit of themselves and the Holders, as the same may be amended or modified from time to time in
accordance with the terms thereof. 
  
 “Resale
Registration Statement” means a registration statement under the Securities Act registering the Securities for resale pursuant to the terms of the Registration Rights Agreement. 
  
 “Responsible Officer” means any officer of the Trustee within the Corporate Trust Office of the Trustee
with direct responsibility for the administration of this Indenture and also, with respect to a particular matter, any other officer of the Trustee to whom such matter is referred because of such officer’s knowledge and familiarity with the
particular subject. 
  
 “Restricted Global
Security” means a Global Security representing Restricted Securities. 
  
 “Restricted Security” or “Restricted Securities” has the meaning specified in Section 2.05. 
  
 “Rights Plan” has the meaning specified in Section 13.06(c). 
  
 “Rule 144” means Rule 144 under the Securities Act (including any successor rule thereto), as the same may
be amended from time to time. 
  
 “Rule 144A”
means Rule 144A under the Securities Act (including any successor rule thereto), as the same may be amended from time to time. 
  
 “Rule 144A Information” has the meaning specified in the Securities. 
  
 “Securities Act” means the U.S. Securities Act of 1933, as amended, and the rules and regulations of the
Commission promulgated thereunder. 
  
 “Security”
or “Securities” has the meaning specified in the first paragraph of the Recitals of the Company. 
  

 8 

 “Security Register” and “Security Registrar” have the respective
meanings specified in Section 3.05. 
  
 “Stated
Maturity,” when used with respect to any Security, means the date specified in such Security as the fixed date on which an amount equal to the principal amount of such Security together with accrued and unpaid interest and Liquidated
Damages, if any, is due and payable. 
  
 “Subsidiary” means a corporation more than 50% of the outstanding voting stock of which is owned, directly or indirectly, by the Company or by one or more other Subsidiaries. For the purposes of this definition,
“voting stock” means stock which ordinarily has voting power for the election of directors, whether at all times or only so long as no senior class of stock has such voting power by reason of any contingency. 
  
 “Surviving Entity” has the meaning specified in Section
8.01. 
  
 “Termination of Trading” means that the
Company’s Common Stock or other common stock into which the Securities are convertible is neither listed for trading on a United States national securities exchange nor approved for listing on the Nasdaq National Market or any similar United
States system of automated dissemination of quotations of securities prices, and no America Depositary Shares or similar instruments for such common stock are so listed or approved for listing in the United States. 
  
 “Trading Day” means (x) if the applicable security is quoted
on the Nasdaq National Market System or Nasdaq SmallCap Market, a day on which trades may be made on thereon or (y) if the applicable security is listed or admitted for trading on the New York Stock Exchange or another national security exchange, a
day on which the New York Stock Exchange or such other national security exchange is open for business or (z) if the applicable security is not so listed, admitted for trading or quoted, any Business Day. 
  
 “Trading Price,” for purposes of calculating the Make-Whole
Premium, on any date of determination means the average of the secondary market bid quotations per Security obtained by the Trustee for $2,000,000 principal amount of the Securities at approximately 3:30 p.m. New York City time, on such
determination date from two independent nationally recognized securities dealers select by the Company, which may include one or more of the Initial Purchasers, provided that if at least two such bids cannot reasonably be obtained by the Trustee,
but one such bid can reasonably be obtained by the Trustee, then one bid will be used. If the Trustee cannot reasonably obtain at least one bid for $2,000,000 principal amount of the Securities from a nationally recognized securities dealer or in
the Company’s reasonable judgment, the bid quotations are not indicative of the secondary market value of the Securities, then the “Trading Price” of the Securities will be deemed to be less than 98% of the applicable conversion rate
of the Securities multiplied by the Closing Price of the Common Stock on such determination date. 
  
 “transfer,” for purposes of Section 3.05, has the meaning specified in Section 3.05. 
  

 9 

 “Transfer Restricted Security” means a Security required to bear the restricted legend
set forth in the form of Security set forth as Exhibit A attached hereto. 
  
 “Trigger Event” has the meaning specified in Section 13.06(c). 
  
 “Triggering Distribution” has the meaning specified in Section 13.06(d). 
  
 “Trust Indenture Act” means the Trust Indenture Act of 1939 as in effect on the date as of which this
Indenture was executed; provided, however, that in the event the Trust Indenture Act of 1939 is amended after such date, “Trust Indenture Act” means, to the extent required by any such amendment, the Trust Indenture Act of 1939 as so
amended. 
  
 “Trustee” means the Person named as
the “Trustee” in the first paragraph of this instrument until a successor Trustee shall have become such pursuant to the applicable provisions of this Indenture, and thereafter “Trustee” shall mean such successor
Trustee. 
  
 “United States” means the United
States of America (including the States and the District of Columbia), its territories, its possessions and other areas subject to its jurisdiction (its “possessions” including Puerto Rico, the U.S. Virgin Islands, Guam, American Samoa,
Wake Island and the Northern Mariana Islands). 
  
 “Vice
President,” when used with respect to the Company or the Trustee, means any vice president, whether or not designated by a number or a word or words added before or after the title “vice president.” 
  
 Section 1.02. Compliance Certificates and Opinions. Upon any
application or request by the Company to the Trustee to take any action under any provision of this Indenture, the Company shall furnish to the Trustee such certificates and opinions as may be required under the Trust Indenture Act. Each such
certificate or opinion shall be given in the form of an Officers’ Certificate, if to be given by an officer of the Company, or an Opinion of Counsel, if to be given by counsel, and shall comply with the requirements of the Trust Indenture Act
and any other requirement set forth in this Indenture. 
  
 Every
certificate or opinion with respect to compliance with a condition or covenant provided for in this Indenture shall include: 
  
 (a) a statement that each individual signing such certificate or opinion has read such covenant or condition and the definitions herein
relating thereto; 
  
 (b) a brief statement as to
the nature and scope of the examination or investigation upon which the statements or opinions contained in such certificate or opinion are based; 
  
 (c) a statement that, in the opinion of each such individual, such individual has made such examination or investigation as is necessary
to enable such individual 

  

 10 

 
to express an informed opinion as to whether or not such covenant or condition has been complied with; and 
  
 (d) a statement as to whether, in the opinion of each such
individual, such condition or covenant has been complied with. 
  
 Section 1.03. Form of Documents Delivered to Trustee. In any case where several matters are required to be certified by, or covered by an opinion of, any specified Person, it is not necessary that all such matters be certified by, or
covered by the opinion of, only one such Person, or that they be so certified or covered by only one document, but one such Person may certify or give an opinion with respect to some matters and one or more other such Persons as to other matters,
and any such Person may certify or give an opinion as to such matters in one or several documents. 
  
 Any certificate or opinion of an officer of the Company may be based, insofar as it relates to legal matters, upon a certificate or opinion of, or
representations by, counsel, unless such officer knows, or in the exercise of reasonable care should know, that the certificate or opinion or representations with respect to the matters upon which his certificate or opinion is based are erroneous.
Any such certificate or Opinion of Counsel may be based, insofar as it relates to factual matters, upon a certificate or opinion of, or representations by, an officer or officers of the Company stating that the information with respect to such
factual matters is in the possession of the Company, unless such counsel knows, or in the exercise of reasonable care should know, that the certificate or opinion or representations with respect to such matters are erroneous. 
  
 Where any Person is required to make, give or execute two or more
applications, requests, consents, certificates, statements, opinions or other instruments under this Indenture, they may, but need not, be consolidated and form one instrument. 
  
 Section 1.04. Acts of Holders; Record Dates. (a) Any request, demand, authorization, direction, notice, consent,
waiver or other action provided by this Indenture to be given or taken by Holders may be embodied in and evidenced by one or more instruments of substantially similar tenor signed by such Holders in person or by agent duly appointed in writing and,
except as herein otherwise expressly provided, such action shall become effective when such instrument or instruments are delivered to the Trustee and, where it is hereby expressly required, to the Company. Such instrument or instruments (and the
action embodied therein and evidenced thereby) are herein sometimes referred to as an “Act” of the Holders signing such instrument or instruments. Proof of execution of any such instrument or of a writing appointing any such agent shall be
sufficient for any purpose of this Indenture and (subject to Section 6.01) conclusive in favor of the Trustee and the Company, if made in the manner provided in this Section. 
  
 (b) The fact and date of the execution by any Person of any such instrument or writing may be proved by the
affidavit of a witness of such execution or by a certificate of a notary public or other officer authorized by law to take acknowledgments of deeds, certifying that the individual signing such instrument or writing acknowledged to him the execution
thereof. Where such execution is by a signer acting in a capacity other than his 

  

 11 

 
individual capacity, such certificate or affidavit shall also constitute sufficient proof of his authority. The fact and date of the execution of any such
instrument or writing, or the authority of the Person executing the same, may also be proved in any other manner which the Trustee reasonably deems sufficient. 
  

(c) The Company may, in the circumstances permitted by the Trust Indenture Act, fix any day as the record date for the purpose of
determining the Holders entitled to give or take any request, demand, authorization, direction, notice, consent, waiver or other action, or to vote on any action, authorized or permitted to be given or taken by Holders. If not set by the Company
prior to the first solicitation of a Holder made by any Person in respect of any such action, or, in the case of any such vote, prior to such vote, the record date for any such action or vote shall be the 30th day (or, if later, the date of the most
recent list of Holders required to be provided pursuant to Section 7.01) prior to such first solicitation or vote, as the case may be. With regard to any record date, only the Holders on such date (or their duly designated proxies) shall be entitled
to give or take, or vote on, the relevant action. 
  
 (d) The ownership of Securities shall be proved by the Security Register. 
  
 (e) Any request, demand, authorization, direction, notice, consent, waiver or other Act of the Holder of any Security shall bind every
future Holder of the same Security and the Holder of every Security issued upon the registration of transfer thereof or in exchange therefor or in lieu thereof in respect of anything done, omitted or suffered to be done by the Trustee or the Company
in reliance thereon, whether or not notation of such action is made upon such Security. 
  
 Section 1.05. Notices, Etc., to Trustee and Company. Any request, demand, authorization, direction, notice, consent, waiver or Act of Holders or other document provided or permitted by this Indenture to be made
upon, given or furnished to, or filed with: 
  
 (i) the Trustee by any Holder or by the Company shall be sufficient for every purpose hereunder if made, given, furnished or filed in writing to or with the Trustee at its Corporate Trust Office; or 
  
 (ii) the Company by the Trustee or by any Holder shall be
sufficient for every purpose hereunder (unless otherwise herein expressly provided) if in writing and mailed, first-class postage prepaid, to the Company addressed to it at the address of its principal office specified in the first paragraph of this
instrument or at any other address previously furnished in writing to the Trustee by the Company, Attention: Secretary. 
  
 Section 1.06. Notice to Holders; Waiver. Where this Indenture provides for notice to Holders of any event, such notice shall be sufficiently given
(unless otherwise herein expressly provided) if in writing and mailed, first-class postage prepaid, to each Holder affected by such event, at such Holder’s address as it appears in the Security Register, not later than the latest date 

  

 12 

 
(if any), and not earlier than the earliest date (if any), prescribed for the giving of such notice. In any case where notice to Holders is given by mail,
neither the failure to mail such notice, nor any defect in any notice so mailed, to any particular Holder shall affect the sufficiency of such notice with respect to other Holders. Where this Indenture provides for notice in any manner, such notice
may be waived in writing by the Person entitled to receive such notice, either before or after the event, and such waiver shall be the equivalent of such notice. Waivers of notice by Holders shall be filed with the Trustee, but such filing shall not
be a condition precedent to the validity of any action taken in reliance upon such waiver. 
  
 In case by reason of the suspension of regular mail service or by reason of any other cause it shall be impracticable to give such notice by mail, then such notification as shall be made with the approval of the
Trustee shall constitute a sufficient notification for every purpose hereunder. 
  
 Whenever under this Indenture the Trustee is required to provide any notice by mail, in all cases the Trustee may alternatively provide notice by overnight courier or by telefacsimile, with confirmation of
transmission. 
  
 Section 1.07. Conflict with Trust Indenture
Act. If any provision hereof limits, qualifies or conflicts with a provision of the Trust Indenture Act that is required hereunder to be a part of and govern this Indenture, the latter provision shall control. If any provision of this Indenture
modifies or excludes any provision of the Trust Indenture Act that may be so modified or excluded, the latter provision shall be deemed to apply to this Indenture as so modified or to be excluded, as the case may be. 
  
 Section 1.08. Effect of Headings and Table of Contents. The Article
and Section headings herein and the Table of Contents are for convenience only and shall not affect the construction hereof, and all Article and Section references are to Articles and Sections, respectively, of this Indenture unless otherwise
expressly stated. 
  
 Section 1.09. Successors and Assigns.
All covenants and agreements in this Indenture by the Company shall bind its successors and assigns, whether so expressed or not. 
  
 Section 1.10. Severability Clause. In case any provision in this Indenture or in the Securities shall be invalid, illegal or unenforceable, the
validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby. 
  
 Section 1.11. Benefits of Indenture. Nothing in this Indenture or in the Securities, express or implied, shall give to any Person, other than the
parties hereto and their respective successors hereunder and the Holders of Securities, any benefit or any legal or equitable right, remedy or claim under this Indenture. 
  
 Section 1.12. Governing Law. This Indenture and the Securities shall be governed by and construed in accordance with
the laws of the State of New York. 
  

 13 

 Section 1.13. Legal Holiday. In any case where any Interest Payment Date or Stated Maturity of any
Security shall not be a Business Day, then (notwithstanding any other provision of this Indenture or of the Securities) payment of interest or principal need not be made on such date, but may be made on the next succeeding Business Day with the same
force and effect as if made on the Interest Payment Date or at the Stated Maturity; provided, that no interest shall accrue with respect to such payment for the period from and after such Interest Payment Date or Stated Maturity, as the case may be.

  
 ARTICLE 2 
 Security Forms 
  
 Section 2.01. Forms Generally. The Securities and the Trustee’s certificates of authentication shall be in substantially the forms set forth
in this Article, with such appropriate insertions, omissions, substitutions and other variations as are required or permitted by this Indenture, and may have such letters, numbers or other marks of identification and such legends or endorsements
placed thereon as may be required to comply with the rules of any securities exchange or Depositary therefor, the Internal Revenue Code of 1986, as amended, and regulations thereunder, or as may, consistently herewith, be determined by the officers
executing such Securities, as evidenced by their execution thereof. 
  
 The Securities shall initially be issued in the form of permanent Global Securities in registered form in substantially the form set forth in this Article. The aggregate Principal Amount of the Global Securities may from time to time be
increased or decreased by adjustments made on the records of the Trustee, as custodian for the Depositary, as hereinafter provided. 
  
 Section 2.02. Form of Face of Security. The face of each Security shall be substantially in the form of Exhibit A attached hereto.

  
 Section 2.03. Form of Reverse of Security. The reverse
of each Security shall be substantially in the form of Exhibit B attached hereto. 
  
 Section 2.04. Form of Trustee’s Certificate of Authentication. No Security shall be entitled to any benefit under this Indenture or be valid or obligatory for any purpose unless there appears on such
Security a certificate of authentication substantially in the form of Exhibit C attached hereto. 
  
 Section 2.05. Legend on Restricted Securities. During the period beginning on the Issue Date and ending on the date two years from such date, any
Security, including any Security issued in exchange therefor or in lieu thereof, shall be deemed a “Restricted Security” and shall be subject to the restrictions on transfer provided in the legends set forth on the face of the form
of Security attached hereto as Exhibit A; provided, however, that the term “Restricted Security” shall not include any Securities as to which restrictions have been terminated in accordance with Section 3.05. All Securities
shall bear the applicable legends set forth on the face of the form of Security attached hereto as Exhibit A. Except as provided in Section 3.05 and Section 3.09, the 

  

 14 

 
Trustee shall not issue any unlegended Security until it has received an Officers’ Certificate from the Company directing it to do so. 
  
 ARTICLE 3 
 The Securities 
  
 Section 3.01. Title and Terms. The aggregate Principal Amount of Securities that may be authenticated and delivered under this Indenture is initially limited to $125,000,000 (subject to increase by up to $18,750,000 in the event the
Initial Purchasers exercise the option granted to them in the Purchase Agreement), except for Securities authenticated and delivered upon registration or transfer of, or in exchange for, or in lieu of, other Securities pursuant to Section 3.04,
3.05, 3.06, 9.06 or 11.04. 
  
 The Securities shall be known and
designated as the “31⁄2% Senior Convertible Notes Due 2011” of the Company. The Principal Amount shall be payable at the Stated Maturity. 
  
 The Principal Amount and accrued interest and Liquidated Damages, if any, on the Securities shall be payable at the office or agency of the Company in The
City of New York maintained for such purpose and at any other office or agency maintained by the Company for such purpose; provided, however, that at the option of the Company payments may be made by wire transfer or by check mailed to the address
of the Person entitled thereto as such address shall appear in the Security Register. 
  
 The Securities shall not have the benefit of a sinking fund. 
  
 The Securities shall not be superior in right of payment to, and shall rank pari passu with, all other unsecured and unsubordinated indebtedness of the Company, except as set forth in Article 14 hereof. 
  
 Section 3.02. Denominations. The Securities shall be issuable only in
registered form without coupons and in denominations of $1,000 and any integral multiple of $1,000 above that amount. 
  
 Section 3.03. Execution, Authentication, Delivery and Dating. The Securities shall be executed on behalf of the Company by its Chairman of the
Board, its President or one of its Vice Presidents. 
  
 Securities
bearing the manual or facsimile signatures of individuals who were at any time the proper officers of the Company shall bind the Company, notwithstanding that such individuals or any of them have ceased to hold such offices prior to the
authentication and delivery of such Securities or did not hold such offices at the date of such Securities. 
  
 At any time and from time to time after the execution and delivery of this Indenture, the Company may deliver Securities executed by the Company to the
Trustee for authentication, together with a Company Order for the authentication and delivery of such Securities. The 

  

 15 

 
Company Order shall specify the amount of Securities to be authenticated, and shall further specify the amount of such Securities to be issued as a Global
Security or as Physical Securities. The Trustee in accordance with such Company Order shall authenticate and deliver such Securities as in this Indenture provided and not otherwise. 
  
 Each Security shall be dated the date of its authentication. 
  
 No Security shall be entitled to any benefit under this Indenture or be valid or obligatory for any purpose unless there
appears on such Security a certificate of authentication substantially in the form provided for herein executed by the Trustee by manual signature, and such certificate upon any Security shall be conclusive evidence, and the only evidence, that such
Security has been duly authenticated and delivered hereunder. 
  
 Section 3.04. Temporary Securities. Pending the preparation of definitive Securities, the Company may execute, and upon Company Order the Trustee shall authenticate and deliver, temporary Securities which are printed, lithographed,
typewritten, mimeographed or otherwise produced, in any authorized denomination, substantially of the tenor of the definitive Securities in lieu of which they are issued and with such appropriate insertions, omissions, substitutions and other
variations as the officers executing such Securities may determine, as evidenced by their execution of such Securities. 
  
 If temporary Securities are issued, the Company will cause definitive Securities to be prepared without unreasonable delay. After the preparation of
definitive Securities, the temporary Securities shall be exchangeable for definitive Securities upon surrender of the temporary Securities at any office or agency of the Company designated pursuant to Section 10.02, without charge to the Holder.
Upon surrender for cancellation of any one or more temporary Securities the Company shall execute and the Trustee shall authenticate and deliver in exchange therefor a like Principal Amount of definitive Securities of authorized denominations. Until
so exchanged, the temporary Securities shall in all respects be entitled to the same benefits under this Indenture as definitive Securities. 
  
 Section 3.05. Registration; Registration of Transfer and Exchange; Restrictions on Transfer. (a) The Company shall cause to be kept at the
Corporate Trust Office of the Trustee a register (the register maintained in such office and in any other office or agency designated pursuant to Section 10.02 being herein sometimes collectively referred to as the “Security
Register”) in which, subject to such reasonable regulations as it may prescribe, the Company shall provide for the registration of Securities and of transfers of Securities. The Trustee is hereby appointed “Security Registrar”
(the “Security Registrar”) for the purpose of registering Securities and transfers of Securities as herein provided. 
  
 Upon surrender for registration of transfer of any Security at an office or agency of the Company designated pursuant to Section 10.02 for such purpose,
the Company shall execute, and the Trustee shall authenticate and deliver, in the name of the designated transferee or transferees, one or more new Securities of any authorized denominations and of a like aggregate 

  

 16 

 
Principal Amount and tenor, each such Security bearing such restrictive legends as may be required by this Indenture (including Sections 2.02, 2.05 and
3.09). 
  
 At the option of the Holder and subject to the other
provisions of this Section 3.05 and to Section 3.09, Securities may be exchanged for other Securities of any authorized denominations and of a like aggregate Principal Amount and tenor, upon surrender of the Securities to be exchanged at such office
or agency. Whenever any Securities are so surrendered for exchange, the Company shall execute, and the Trustee shall authenticate and deliver, the Securities which the Holder making the exchange is entitled to receive. 
  
 All Securities issued upon any registration of transfer or exchange of
Securities shall be the valid obligations of the Company, evidencing the same debt, and entitled to the same benefits under this Indenture, as the Securities surrendered upon such registration of transfer or exchange. 
  
 Every Security presented or surrendered for registration of transfer or for
exchange shall (if so required by the Company or the Trustee) be duly endorsed, or be accompanied by a written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed, by the Holder thereof or his attorney
duly authorized in writing. As a condition to the registration of transfer of any Restricted Securities, the Company or the Trustee may require evidence satisfactory to them as to the compliance with the restrictions set forth in the legend on such
securities. 
  
 Except as provided in the following sentence and
in Section 3.09, all Securities originally issued hereunder and all Securities issued upon registration of transfer or exchange or replacement thereof shall be Restricted Securities and shall bear the legend required by Sections 2.02 and 2.05,
unless the Company shall have delivered to the Trustee (and the Security Registrar, if other than the Trustee) a Company Order stating that the Security is not a Restricted Security and may be issued without such legend thereon. Securities which are
issued upon registration of transfer of, or in exchange for, Securities which are not Restricted Securities shall not be Restricted Securities and shall not bear such legend. 
  
 No service charge shall be made for any registration of transfer or exchange of Securities, but the Company may require
payment of a sum sufficient to cover any tax or other governmental charge that may be imposed in connection with any registration of transfer or exchange of Securities, other than exchanges pursuant to Section 3.04 not involving any transfer.

  
 The Company shall not be required to exchange or register a
transfer of any Security (i) during the 15-day period immediately preceding the mailing of any notice of redemption of any Security, (ii) after any notice of redemption has been given to Holders, except, where such notice provides that such Security
is to be redeemed only in part, the Company shall be required to exchange or register a transfer of the portion thereof not to be redeemed, (iii) that has been surrendered for conversion or (iv) as to which a Fundamental Change Repurchase Notice has
been delivered and not withdrawn, except, where such Fundamental Change Repurchase Notice provides that such Security is to be purchased only in part, the Company shall be required to exchange or register a transfer of the portion thereof not to be
purchased. 
  

 17 

 (b) Beneficial ownership of every Restricted Security shall be subject to the
restrictions on transfer provided in the legends required to be set forth on the face of each Restricted Security pursuant to Sections 2.02 and 2.05, unless such restrictions on transfer shall be terminated in accordance with this Section 3.05(b) or
Section 3.09. The Holder of each Restricted Security, by such Holder’s acceptance thereof, agrees to be bound by such restrictions on transfer. 
  
 The restrictions imposed by this Section 3.05 and by Sections 2.02, 2.05 and 3.09 upon the transferability of any particular Restricted Security shall
cease and terminate upon delivery by the Company to the Trustee of an Officers’ Certificate stating that such Restricted Security has been sold pursuant to an effective Resale Registration Statement under the Securities Act or transferred in
compliance with Rule 144 under the Securities Act (or any successor provision thereto). Any Restricted Security as to which the Company has delivered to the Trustee an Officers’ Certificate that such restrictions on transfer shall have expired
in accordance with their terms or shall have terminated may, upon surrender of such Restricted Security for exchange to the Security Registrar in accordance with the provisions of this Section 3.05, be exchanged for a new Security, of like tenor and
aggregate Principal Amount, which shall not bear the restrictive legends required by Sections 2.02 and 2.05. The Company shall inform the Trustee in writing of the effective date of any Resale Registration Statement registering the Securities under
the Securities Act. The Trustee shall not be liable for any action taken or omitted to be taken by it in good faith in accordance with the aforementioned Resale Registration Statement. 
  
 As used in the preceding two paragraphs, the term “transfer” encompasses any sale, pledge, transfer or
other disposition of any Restricted Security. 
  
 (c) Neither the Trustee nor any of its agents shall (i) have any duty to monitor compliance with or with respect to any federal or state or other securities or tax laws or (ii) have any duty to obtain documentation relating to any transfers
or exchanges other than as specifically required hereunder. 
  
 Section 3.06. Mutilated, Destroyed, Lost and Stolen Securities. If any mutilated Security is surrendered to the Trustee, the Company shall execute and the Trustee shall authenticate and deliver in exchange therefor a new Security of
like tenor and Principal Amount and bearing a number not contemporaneously outstanding. 
  
 If there shall be delivered to the Company and the Trustee (i) evidence to their satisfaction of the destruction, loss or theft of any Security and (ii) such security or indemnity as may be required by them to save
each of them and any agent of either of them harmless, then, in the absence of notice to the Company or the Trustee that such Security has been acquired by a bona fide purchaser, the Company shall execute and the Trustee shall authenticate and
deliver, in lieu of any such destroyed, lost or stolen Security, a new Security of like tenor and Principal Amount and bearing a number not contemporaneously outstanding. 
  

 18 

 In case any such mutilated, destroyed, lost or stolen Security has become or is about to become due and
payable or has been called for redemption in full, the Company in its discretion may, instead of issuing a new Security, pay such Security. 
  
 Upon the issuance of any new Security under this Section 3.06, the Company may require payment by the Holder of a sum sufficient to cover any tax or other
governmental charge that may be imposed in relation thereto and any other expenses (including the fees and expenses of the Trustee) connected therewith. 
  
 Every new Security issued pursuant to this Section 3.06 in lieu of any destroyed, lost or stolen Security shall constitute an original additional
contractual obligation of the Company, whether or not the destroyed, lost or stolen Security shall be at any time enforceable by anyone, and shall be entitled to all the benefits of this Indenture equally and proportionately with any and all other
Securities duly issued hereunder. 
  
 The provisions of this
Section are exclusive and shall preclude (to the extent lawful) all other rights and remedies with respect to the replacement or payment of mutilated, destroyed, lost or stolen Securities. 
  
 Section 3.07. Persons Deemed Owners. Prior to due presentment of a
Security for registration of transfer, the Company, the Trustee and any agent of the Company or the Trustee may treat the Person in whose name such Security is registered as the owner of such Security for the purpose of receiving payment of the
principal of and interest and Liquidated Damages, if any, on such Security and for all other purposes whatsoever, whether or not such Security be overdue, and neither the Company, the Trustee nor any agent of the Company or the Trustee shall be
affected by notice to the contrary. 
  
 Section 3.08.
Book-Entry Provisions for Global Securities. (a) The Global Securities initially shall (i) be registered in the name of the Depositary or the nominee of such Depositary, (ii) be delivered to the Trustee as custodian for the Depositary and
(iii) bear legends as set forth on the face of the form of Security in Section 2.02. 
  
 (b) Members of, or participants in, the Depositary (“Agent Members”) shall have no rights under this Indenture with
respect to any Global Security held on their behalf by the Depositary, or the Trustee as its custodian, or under the Global Security, and the Depositary may be treated by the Company, the Trustee and any agent of the Company or the Trustee as the
absolute owner of the Global Security for all purposes whatsoever. Notwithstanding the foregoing, nothing herein shall prevent the Company, the Trustee or any agent of the Company or the Trustee from giving effect to any written certification, proxy
or other authorization furnished by the Depositary or impair, as between the Depositary and its Agent Members, the operation of customary practices governing the exercise of the rights of any Holder. 
  
 (c) Transfers of the Global Securities shall be limited to
transfers in whole, but not in part, to the Depositary, its successors or their respective nominees. Interests of 

  

 19 

 
beneficial owners in a Global Security may be transferred or exchanged, in whole or in part, for Physical Securities in accordance with the rules and
procedures of the Depositary and the provisions of Section 3.09. In addition, Physical Securities shall be transferred to all beneficial owners in exchange for their beneficial interests in the Global Securities if (A) such Depositary has notified
the Company (or the Company becomes aware) that the Depositary (i) is unwilling or unable to continue as Depositary for such Global Security or (ii) has ceased to be a clearing agency registered under the Exchange Act when the Depositary is required
to be so registered to act as such Depositary and, in either such case, no successor Depositary shall have been appointed within 90 days of such notification or of the Company becoming aware of such event; or (B) there shall have occurred and be
continuing an Event of Default with respect to such Global Security and the Outstanding Securities shall have become due and payable pursuant to Section 5.02 and the Trustee requests that Physical Securities be issued; provided that Holders of
Physical Securities offered and sold in reliance on Rule 144A shall have the right, subject to applicable law, to request that such Securities be exchanged for interests in the applicable Global Security. 
  
 (d) In connection with any transfer or exchange of a portion
of the beneficial interest in the Global Security to beneficial owners pursuant to clause (b) of this Section 3.08, the Security Registrar shall (if one or more Physical Securities are to be issued) reflect on its books and records the date and a
decrease in the Principal Amount of the Global Security in an amount equal to the Principal Amount of the beneficial interest in the Global Security to be transferred, and the Company shall execute, and the Trustee shall authenticate and deliver,
one or more Physical Securities of like tenor and amount. 
  
 (e) In connection with the transfer of the entire Global Security to beneficial owners pursuant to clause (b) of this Section 3.08, the Global Security shall be deemed to be surrendered to the Trustee for
cancellation, and the Company shall execute, and the Trustee shall authenticate and deliver, to each beneficial owner identified by the Depositary in exchange for its beneficial interest in the Global Security, an equal aggregate Principal Amount of
Physical Securities of authorized denominations and the same tenor. 
  
 (f) Any Physical Security constituting a Restricted Security delivered in exchange for an interest in the Global Security pursuant to clause (c) or (d) of this Section 3.08 shall, except as otherwise provided by
clause (c) of Section 3.09, bear the legend regarding transfer restrictions applicable to the Physical Securities set forth on the face of the form of Security in Section 2.02. 
  
 (g) The Holder of the Global Securities may grant proxies and otherwise authorize any Person, including
Agent Members and Persons that may hold interests through Agent Members, to take any action which a Holder is entitled to take under this Indenture or the Securities. 
  
 (h) The Trustee shall have no responsibility or obligation to any beneficial owner of a Global Security, a
member or, or a participant in the Depositary or other Person with respect to the accuracy of the books or records, or the acts or omissions, of the 

  

 20 

 
Depositary or its nominee or of any participant or member thereof, with respect to any ownership interest in the Securities or with respect to the delivery
to any participant, member, beneficial owner or other Person (other than the Depositary) of any notice (including any notice of redemption) or the payment of any amount, under or with respect to such Securities. All notices and communications to be
given to the Holders and all payment to be made to Holders under the Securities shall be given or made only to or upon the order of the registered Holders (which shall be the Depositary or its nominee in the case of a Global Security). The rights of
beneficial owners in any Global Security shall be exercised only through the Depositary subject to the applicable procedures of the Depositary. The Trustee may rely on information furnished by the Depositary with respect to its members, participants
and any beneficial owners. 
  
 Section 3.09. Cancellation and
Transfer Provisions. The Company at any time may deliver to the Trustee for cancellation any Securities previously authenticated and delivered hereunder which the Company may have acquired in any manner whatsoever, and may deliver to the Trustee
for cancellation any Securities previously authenticated hereunder which the Company has not issued and sold. The Trustee shall cancel and dispose of all Securities surrendered for registration of transfer, exchange, payment, purchase, repurchase,
redemption, conversion (pursuant to Article 13 hereof) or cancellation in accordance with its customary practices. If the Company shall acquire any of the Securities, such acquisition shall not operate as a redemption or satisfaction of the
indebtedness represented by such Securities unless and until the same are delivered to the Trustee for cancellation. The Company may not issue new Securities to replace Securities it has paid in full or delivered to the Trustee for cancellation.

  
 (a) Transfers to QIBs. The following
provisions shall apply with respect to the registration of any proposed transfer of a Security constituting a Restricted Security to a QIB: 
  
 (i) the Security Registrar shall register the transfer if such transfer is being made by a proposed transferor who has checked the box
provided for on the form of Security stating, or has otherwise advised the Company and the Security Registrar in writing, that the sale has been made in compliance with the provisions of Rule 144A to a transferee who has signed the certification
provided for on the form of Security stating, or has otherwise advised the Company and the Security Registrar in writing, that it is purchasing the Security for its own account or an account with respect to which it exercises sole investment
discretion and that it and any such account is a QIB within the meaning of Rule 144A, and is aware that the sale to it is being made in reliance on Rule 144A and acknowledges that it has received such information regarding the Company as it has
requested pursuant to Rule 144A or has determined not to request such information and that it is aware that the transferor is relying upon its foregoing representations in order to claim the exemption from registration provided by Rule 144A; and

  
 (ii) if the proposed transferee is an Agent
Member, and the Securities to be transferred consist of Physical Securities which after transfer are 

  

 21 

 
to be evidenced by an interest in the Global Security, upon receipt by the Security Registrar of instructions given in accordance with the Depositary’s
and the Security Registrar’s procedures, the Security Registrar shall reflect on its books and records the date and an increase in the Principal Amount of the Global Security in an amount equal to the Principal Amount of the Physical Securities
to be transferred, and the Trustee shall cancel the Physical Securities so transferred. 
  
 (b) Private Placement Legend. Upon the registration of transfer, exchange or replacement of Securities not bearing the legends
required by Sections 2.02 and 2.05, the Security Registrar shall deliver Securities that do not bear such legends. Upon the registration of transfer, exchange or replacement of Securities bearing the legends required by Sections 2.02 and 2.05, the
Security Registrar shall deliver only Securities that bear such legends unless there is delivered to the Security Registrar an Opinion of Counsel reasonably satisfactory to the Company and the Trustee to the effect that neither such legend nor the
related restrictions on transfer are required in order to maintain compliance with the provisions of the Securities Act. 
  
 (c) General. By its acceptance of any Security bearing the legends required by Sections 2.02 and 2.05, each Holder of such a
Security acknowledges the restrictions on transfer of such Security set forth in this Indenture and in such legends and agrees that it will transfer such Security only as provided in this Indenture. 
  
 The Security Registrar shall retain, in accordance with its customary
procedures, copies of all letters, notices and other written communications received pursuant to this Section 3.09. The Company shall have the right to inspect and make copies of all such letters, notices or other written communications at any
reasonable time upon the giving of reasonable written notice to the Security Registrar. 
  
 The Trustee shall have no obligation or duty to monitor, determine or inquire as to compliance with any restrictions on transfer imposed under this Indenture or under applicable law with respect to any transfer of any
interest in any Security (including any transfers between or among Depositary participants, members or beneficial owners in any Global Security) other than to require delivery of such certificates and other documentation or evidence as are expressly
required by the terms of this Indenture, and to examine the same to determine substantial compliance as to form with the express requirements hereof. 
  
 Section 3.10. CUSIP Numbers. In issuing the Securities, the Company may use “CUSIP” numbers (if then generally in use), and, if so, the
Trustee shall use “CUSIP” numbers in notices of redemption as a convenience to Holders; provided that any such notice may state that no representation is made as to the correctness of such numbers either as printed on the Securities or as
contained in any notice of a redemption and that reliance may be placed only on the other identification numbers printed on the Securities, and any such redemption shall not be affected by any defect in or omission of such numbers. The Company will
promptly notify the Trustee of any change in the “CUSIP” numbers. 
  

 22 

 ARTICLE 4 
 Satisfaction And Discharge 
  
 Section 4.01. Satisfaction and Discharge of Indenture. This Indenture shall cease to be of further effect (except as to any surviving rights of registration of transfer or exchange of Securities herein expressly provided for), and
the Trustee, on demand of and at the expense of the Company, shall execute proper instruments acknowledging satisfaction and discharge of this Indenture, when 
  

(a) either 
  
 (i) all Securities theretofore authenticated and delivered (other than (A) Securities which have been destroyed, lost or stolen and which
have been replaced or paid as provided in Section 3.06 and (B) Securities for whose payment money has theretofore been deposited with the Trustee in trust or segregated and held in trust by the Company and thereafter repaid to the Company or
discharged from such trust as provided in Section 10.03) have been delivered to the Trustee for cancellation; or 
  
 (ii) all such Securities not theretofore delivered to the Trustee for cancellation have become due and payable and the Company has
deposited or caused to be deposited with the Trustee as trust funds in trust for the purpose an amount sufficient to pay and discharge the entire indebtedness evidenced by such Securities not theretofore delivered to the Trustee for cancellation;

  
 (b) the Company has paid or caused to be paid
all other sums payable hereunder by the Company; and 
  
 (c) the Company has delivered to the Trustee an Officers’ Certificate and an Opinion of Counsel, each stating that all conditions precedent herein provided for relating to the satisfaction and discharge of this Indenture have been
complied with. 
  
 Notwithstanding the satisfaction and discharge
of this Indenture, the obligations of the Company to the Trustee under Section 6.07 and, if money shall have been deposited with the Trustee pursuant to clause (a)(ii) of Section 4.01, the obligations of the Trustee under Section 4.02 and the last
paragraph of Section 10.03 shall survive such satisfaction and discharge. 
  
 Section 4.02. Application of Trust Money. Subject to the provisions of the last paragraph of Section 10.03, all money deposited with the Trustee pursuant to Section 4.01 shall be held in trust and applied by
it, in accordance with the provisions of the Securities and this Indenture, to the payment, either directly or through any Paying Agent (including the Company acting as its own Paying Agent) as the Trustee may determine, to the Persons entitled
thereto, of the principal, interest and Liquidated Damages, if any, for whose payment such money has been deposited with the Trustee. 
  

 23 

 ARTICLE 5 
 Remedies 
  
 Section 5.01.
Events of Default. “Event of Default,” wherever used herein, means any one of the following events (whatever the reason for such Event of Default and whether it shall be voluntary or involuntary or be effected by operation of
law or pursuant to any judgment, decree or order of any court or any order, rule or regulation of any administrative or governmental body): 
  
 (a) default in the payment of interest (other than the first six scheduled interest payments up to and including the interest payment due
on April 15, 2007) or Liquidated Damages, if any, on any Securities when due and payable and such default continues for a period of 30 days; or 
  
 (b) default in the payment of the Principal Amount, Redemption Price, Fundamental Change Repurchase Price or the first six scheduled
interest payments up to and including the interest payment due on April 15, 2007 on any Security when it becomes due and payable; or 
  
 (c) default in the performance of any covenant, agreement or condition of the Company in this Indenture or the Securities (other than a
default specified in clause (a) or (b) above), and such default continues for a period of 60 days after there has been given, by registered or certified mail, to the Company by the Trustee or to the Company and the Trustee by the Holders of at least
25% in aggregate Principal Amount of the Outstanding Securities a written notice specifying such default and requiring it to be remedied and stating that such notice is a “Notice of Default” hereunder; or 
  
 (d) default in the Company’s obligation to convert the
Securities into shares of its Common Stock upon exercise of a Holder’s conversion rights in accordance with Article 13 hereof and such default continues for a period of 10 days; or 
  
 (e) default by the Company or any Subsidiary in the payment of the principal or interest on any loan
agreement or other instrument under which there may be outstanding, or by which there may be evidenced, any debt for money borrowed in excess of $7.5 million in the aggregate of the Company and any Subsidiary (other than indebtedness for borrowed
money secured only by the real property to which the indebtedness relates and which is non-recourse to the Company or to such Subsidiary), whether such debt now exists or shall hereafter be created, resulting in such debt becoming or being declared
due and payable prior to its stated maturity, and such acceleration shall not have been rescinded or annulled within 30 days after written notice has been received by the Company or such Subsidiary from the Trustee or by the Trustee, the Company and
such Subsidiary by the Holders of at least 25% in Principal Amount of Outstanding Securities; provided that if any time before a judgment or decree has been obtained by the Trustee as hereinafter provided, such default is remedied or cured by the
Company within the applicable cure period, or is waived by the holders of such indebtedness, 

  

 24 

 
default under this clause (e) shall be deemed to have been remedied, cured or waived, as the case may be; or 
  
 (f) failure by the Company to give the Fundamental Change
Company Notice; or 
  
 (g) the entry by a court
having jurisdiction in the premises of (i) a decree or order for relief in respect of the Company of a voluntary case or proceeding under any applicable Federal or State bankruptcy, insolvency, reorganization or other similar law or (ii) a decree or
order adjudging the Company as bankrupt or insolvent, or approving as properly filed a petition seeking reorganization, arrangement, adjustment or composition of or in respect of the Company under any applicable Federal or State law or (iii)
appointing a custodian, receiver, liquidator, assignee, trustee, sequestrator or other similar official of the Company or of any substantial part of its property, or ordering the winding up or liquidation of its affairs, and the continuance of any
such decree or order for relief or any such other decree or order unstayed and in effect for a period of 60 consecutive days; or 
  
 (h) the commencement by the Company of a voluntary case or proceeding under any applicable Federal or State bankruptcy, insolvency,
reorganization or other similar law or of any other case or proceeding to be adjudicated a bankrupt or insolvent, or the consent by it to the entry of a decree or order for relief in respect of the Company in an involuntary case or proceeding under
any applicable Federal or State bankruptcy, insolvency, reorganization or other similar law or to the commencement of any bankruptcy or insolvency case or proceeding against it, or the filing by it of a petition or answer or consent seeking
reorganization or relief under any applicable Federal or State law, or the consent by it to the filing of such petition or to the appointment of or taking possession by a custodian, receiver, liquidator, assignee, trustee, sequestrator or other
similar official of the Company or of any substantial part of its property, or the making by it of an assignment for the benefit of creditors, or the admission by it in writing of its inability to pay its debts generally as they become due, or the
taking of corporate action by the Company in furtherance of any such action; or 
  
 (i) the Pledge Agreement shall cease to be in full force and effect or enforceable prior to the expiration thereof in accordance with its
terms. 
  
 Section 5.02. Acceleration of Maturity; Rescission
and Annulment. (a) If an Event of Default (other than those specified in clauses (g) and (h) of Section 5.01) occurs and is continuing, then and in every such case the Trustee or the Holders of not less than 25% in aggregate Principal Amount of
the Outstanding Securities may declare the Principal Amount plus accrued and unpaid interest and Liquidated Damages, if any, on all the Outstanding Securities to be due and payable immediately, by a notice in writing to the Company (and to the
Trustee if given by Holders), and upon any such declaration such Principal Amount plus accrued and unpaid interest and Liquidated Damages, if any, shall become immediately due and payable. 
  
 Notwithstanding the foregoing, in the case of an Event of Default specified
in clauses (g) and (h) of Section 5.01, the Principal Amount plus accrued and unpaid interest and Liquidated 

  

 25 

 
Damages, if any, on all Outstanding Securities will ipso facto become due and payable without any declaration or other Act on the part of the Trustee or any
Holder. 
  
 (b) At any time after such a
declaration of acceleration has been made and before a judgment or decree for payment of the money due has been obtained by the Trustee as hereinafter in this Article 5 provided, the Holders of a majority in aggregate Principal Amount of the
Outstanding Securities, by written notice to the Company and the Trustee, may rescind and annul such declaration and its consequences if such rescission and annulment will not conflict with any judgment or decree of a court of competent jurisdiction
and: 
  
 (i) the Company has paid or deposited
with the Trustee a sum sufficient to pay 
  
 (A)
all overdue interest on the Securities, 
  
 (B)
the Principal Amount plus accrued and unpaid interest and Liquidated Damages, if any, Redemption Price or Fundamental Change Repurchase Price, as applicable, on any Securities which have become due otherwise than by such declaration of acceleration,
and 
  
 (C) all sums paid or advanced by the
Trustee hereunder and the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel and any other amounts due the Trustee under Section 6.07; and 
  
 (ii) all Events of Default, other than the non-payment of
the Principal Amount plus accrued and unpaid interest and Liquidated Damages, if any, on Securities which have become due solely by such declaration of acceleration, have been cured or waived as provided in Section 5.12. 
  
 No such rescission shall affect any subsequent default or impair any right
consequent thereon. 
  
 Section 5.03. Collection of
Indebtedness and Suits for Enforcement by Trustee. The Company covenants that if a default is made in the payment of the Principal Amount plus accrued and unpaid interest and Liquidated Damages, if any, at the Maturity thereof or in the payment
of the Redemption Price or the Fundamental Change Repurchase Price in respect of any Security, the Company will, upon demand of the Trustee, pay to it, for the benefit of the Holders of such Securities, the whole amount then due and payable on such
Securities, and, in addition thereto, such further amount as shall be sufficient to cover the costs and expenses of collection, including the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel.

  

 26 

 If an Event of Default occurs and is continuing, the Trustee may, but shall not be obligated to, pursue
any available remedy to collect the payment of the principal amount plus accrued but unpaid interest and Liquidated Damages, if any, on the Securities or to enforce the performance of any provision of the Securities or this Indenture. The Trustee
may maintain a proceeding even if the Trustee does not possess any of the Securities or does not produce any of the Securities in the proceeding. A delay or omission by the Trustee or any Holder in exercising any right or remedy accruing upon an
Event of Default shall not impair the right or remedy or constitute a waiver of, or acquiescence in, the Event of Default. No remedy is exclusive of any other remedy. All available remedies are cumulative. 
  
 Section 5.04. Trustee May File Proofs of Claim. In case of any
judicial proceeding relative to the Company (or any other obligor upon the Securities), its property or its creditors, the Trustee shall be entitled and empowered, by intervention in such proceeding or otherwise, to take any and all actions
authorized under the Trust Indenture Act in order to have claims of the Holders and the Trustee allowed in any such proceeding. In particular, the Trustee shall be authorized to collect and receive any moneys or other property payable or deliverable
on any such claims and to distribute the same; and any custodian, receiver, assignee, trustee, liquidator, sequestrator or other similar official in any such judicial proceeding is hereby authorized by each Holder to make such payments to the
Trustee and, in the event that the Trustee shall consent to the making of such payments directly to the Holders, to pay to the Trustee any amount due it for the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents
and counsel and any other amounts due the Trustee under Section 6.07. 
  
 No provision of this Indenture shall be deemed to authorize the Trustee to authorize or consent to or accept or adopt on behalf of any Holder any plan of reorganization, arrangement, adjustment or composition affecting the Securities or the
rights of any Holder thereof or to authorize the Trustee to vote in respect of the claim of any Holder in any such proceeding. 
  
 The Trustee shall be entitled to participate as a member of any official committee of creditors of the Company as it deems necessary or advisable.

  
 Section 5.05. Application of Money Collected. Any money
collected by the Trustee pursuant to this Article shall be applied in the following order, at the date or dates fixed by the Trustee and, in case of the distribution of such money to Holders, upon presentation of the Securities and the notation
thereon of the payment if only partially paid and upon surrender thereof if fully paid: 
  
 FIRST: To the payment of all amounts due the Trustee under Section 6.07; 
  
 SECOND: To the payment of the amounts then due and unpaid on the Securities for the Principal Amount,
Redemption Price, Fundamental Change Repurchase Price or interest and Liquidated Damages, if any, as the case may be, in respect of which or for the benefit of which such 

  

 27 

 
money has been collected, ratably, without preference or priority of any kind, according to the amounts due and payable on such Securities; and 

 
 THIRD: To the Company. 
  
 Section 5.06. Limitation on Suits. No Holder of any Security shall
have any right to institute any proceeding, judicial or otherwise, with respect to this Indenture, or for the appointment of a receiver or trustee, or for any other remedy hereunder (other than in the case of an Event of Default specified in clause
(a) or (b) of Section 5.01), unless: 
  
 (i) such
Holder has previously given written notice to the Trustee of a continuing Event of Default; 
  
 (ii) the Holders of not less than 25% in aggregate Principal Amount of the Outstanding Securities shall have made written request to the
Trustee to institute proceedings in respect of such Event of Default in its own name as Trustee hereunder; 
  
 (iii) such Holder or Holders have offered to the Trustee indemnity reasonably satisfactory to it against the costs, expenses and
liabilities to be incurred in compliance with such request; 
  
 (iv) the Trustee for 60 days after its receipt of such notice, request and offer of security or indemnity has failed to institute any such proceeding; and 
  
 (v) no direction, in the opinion of the Trustee, inconsistent with such written request has been given to
the Trustee during such 60-day period by the Holders of a majority in aggregate Principal Amount of the Outstanding Securities; 
  
 it being understood and intended that no one or more Holders shall have any right in any manner whatever by virtue of, or by availing itself of, any provision of this
Indenture to affect, disturb or prejudice the rights of any other Holders, or to obtain or to seek to obtain priority or preference over any other Holders or to enforce any right under this Indenture, except in the manner herein provided and for the
equal and ratable benefit of all the Holders. 
  
 Section 5.07.
Unconditional Right of Holders to Receive Payment. Notwithstanding any other provision of this Indenture, the right of any Holder to receive payment of the Principal Amount, Redemption Price, Fundamental Change Repurchase Price or interest
and Liquidated Damages, if any, in respect of the Securities held by such Holder, on or after the respective due dates expressed in the Securities or any Redemption Date or Fundamental Change Repurchase Date, as applicable, and to convert the
Securities in accordance with Article 13, or to bring suit for the enforcement of any such payment on or after such respective dates or the right to convert, shall not be impaired or affected adversely without the consent of such Holder. 

 

 28 

 Section 5.08. Restoration of Rights and Remedies. If the Trustee or any Holder has instituted any
proceeding to enforce any right or remedy under this Indenture and such proceeding has been discontinued or abandoned for any reason, or has been determined adversely to the Trustee or to such Holder, then and in every such case, subject to any
determination in such proceeding, the Company, the Trustee and the Holders shall be restored severally and respectively to their former positions hereunder and thereafter all rights and remedies of the Trustee and the Holders shall continue as
though no such proceeding had been instituted. 
  
 Section 5.09.
Rights and Remedies Cumulative. Except as otherwise provided with respect to the replacement or payment of mutilated, destroyed, lost or stolen Securities in the last paragraph of Section 3.06, no right or remedy herein conferred upon or
reserved to the Trustee or to the Holders is intended to be exclusive of any other right or remedy, and every right and remedy shall, to the extent permitted by law, be cumulative and in addition to every other right and remedy given hereunder or
now or hereafter existing at law or in equity or otherwise. The assertion or employment of any right or remedy hereunder shall not prevent the concurrent assertion or employment of any other appropriate right or remedy. 
  
 Section 5.10. Delay or Omission Not Waiver. No delay or omission of
the Trustee or of any Holder of any Security to exercise any right or remedy accruing upon any Event of Default shall impair any such right or remedy or constitute a waiver of any such Event of Default or an acquiescence therein. Every right and
remedy given by this Article or by law to the Trustee or to the Holders may be exercised from time to time, and as often as may be deemed expedient, by the Trustee or by the Holders, as the case may be. 
  
 Section 5.11. Control by Holders. The Holders of a majority in
Principal Amount of the Outstanding Securities shall have the right to direct the time, method and place of conducting any proceeding for any remedy available to the Trustee or exercising any trust or power conferred on the Trustee, provided that:

  
 (i) such direction shall not be in conflict
with any rule of law or with this Indenture; 
  
 (ii) the Trustee may take any other action deemed proper by the Trustee which is not inconsistent with such direction; and 
  
 (iii) the Trustee may refuse to follow any direction that may involve the Trustee in personal liability for which the Trustee would not
otherwise be entitled to indemnification pursuant to the terms of this Indenture. 
  
 Section 5.12. Waiver of Past Defaults. The Holders of not less than a majority in Principal Amount of the Outstanding Securities may on behalf of the Holders of all the Securities waive any past Default
hereunder and its consequences, except a Default: 
  
 (i) Described in clause (a) or (b) of Section 5.01; or 
  

 29 

 (ii) in respect of a covenant or provision hereof which under Article 9 cannot be
modified or amended without the consent of the Holder of each Outstanding Security affected. 
  
 Upon any such waiver, such Default shall cease to exist, and any Event of Default arising therefrom shall be deemed to have been cured, for every purpose of this Indenture; but no such waiver shall extend to any
subsequent or other Default or impair any right consequent thereon. 
  
 Section 5.13. Undertaking for Costs. In any suit for the enforcement of any right or remedy under this Indenture or in any suit against the Trustee for any action taken or omitted by it as Trustee, in either case in respect of the
Securities, a court may require any party litigant in such suit to file an undertaking to pay the costs of the suit, and the court may assess reasonable costs, including reasonable attorney’s fees, and expenses, against any party litigant in
the suit having due regard to the merits and good faith of the claims or defenses made by the party litigant; but the provisions of this Section 5.13 shall not apply to any suit instituted by the Company, to any suit instituted by the Trustee, to
any suit instituted by any Holder, or group of Holders, holding in the aggregate more than 10% in Principal Amount of the Outstanding Securities, or to any suit instituted by any Holder for the enforcement of the payment of the Principal Amount or
interest or Liquidated Damages on any Security on or after Maturity of such Security, the Redemption Price or the Fundamental Change Repurchase Price. 
  
 Section 5.14. Waiver of Stay or Extension Laws. The Company covenants (to the extent that it may lawfully do so) that it will not at any time
insist upon, or plead, or in any manner whatsoever claim or take the benefit or advantage of, any stay, or extension law wherever enacted, now or at any time hereafter in force, which may affect the covenants or the performance of this Indenture;
and the Company (to the extent that it may lawfully do so) hereby expressly waives all benefit or advantage of any such law and covenants that it will not hinder, delay or impede the execution of any power herein granted to the Trustee, but will
suffer and permit the execution of every such power as though no such law had been enacted. 
  
 ARTICLE 6 
 The Trustee 
  
 Section 6.01. Certain Duties and Responsibilities. The duties and responsibilities of the Trustee shall be as
provided by the Trust Indenture Act. Except during the continuance of an Event of Default, the Trustee undertakes to perform such duties and only such duties as are specifically set forth in this Indenture, and no implied covenants or obligations
shall be read into this Indenture against the Trustee. In case an Event of Default with respect to the Securities has occurred (which has not been cured or waived), the Trustee shall exercise the rights and powers vested in it by this Indenture, and
use the same degree of care and skill in their exercise, as a prudent person would exercise or use under the circumstances in the conduct of such person’s own affairs. Notwithstanding the foregoing, no provision of this Indenture shall require
the Trustee to expend or risk its own funds or otherwise incur any financial liability in the performance of any of its duties hereunder, or in the exercise of any of its rights or powers, except to the extent the Trustee is entitled to
reimbursement hereunder. Whether or not therein 

  

 30 

 
expressly so provided, every provision of this Indenture relating to the conduct or affecting the liability of or affording protection to the Trustee shall
be subject to the provisions of this Section 6.01. 
  
 Section
6.02. Notice of Defaults. The Trustee shall give the Holders notice of any Default hereunder within 60 days after the occurrence thereof; provided, that (except in the case of any Default in the payment of Principal Amount or interest and
Liquidated Damages, if any, on any of the Securities, Redemption Price or Fundamental Change Repurchase Price), the Trustee shall be protected in withholding such notice if and so long as a trust committee of directors or trustees and/or a
Responsible Officer of the Trustee in good faith determines that the withholding of such notice is in the interest of the Holders of Securities. 
  
 Section 6.03. Certain Rights Of Trustee. Subject to the provisions of Section 6.01: 
  
 (a) the Trustee may conclusively rely and shall be protected in acting or refraining from acting upon any
resolution, certificate, statement, instrument, opinion, report, notice, request, direction, consent, order, bond, debenture, note, other evidence of indebtedness or other paper or document believed by it to be genuine and to have been signed or
presented by the proper party or parties; 
  
 (b)
any request or direction of the Company mentioned herein shall be sufficiently evidenced by a Company Request or Company Order and any resolution of the Board of Directors of the Company may be sufficiently evidenced by a Board Resolution;

  
 (c) whenever in the administration of this
Indenture the Trustee shall deem it desirable that a matter be proved or established prior to taking, suffering or omitting any action hereunder, the Trustee (unless other evidence be herein specifically prescribed) may, in the absence of bad faith
on its part, request and rely upon an Officers’ Certificate; 
  
 (d) the Trustee may consult with counsel of its selection and the advice of such counsel or any Opinion of Counsel shall be full and complete authorization and protection in respect of any action taken, suffered or
omitted by it hereunder in good faith and in reliance thereon; 
  
 (e) the Trustee shall be under no obligation to exercise any of the rights or powers vested in it by this Indenture at the request or direction of any of the Holders pursuant to this Indenture, unless such Holders
shall have offered to the Trustee security or indemnity reasonably satisfactory to it against the costs, expenses and liabilities which might be incurred by it in compliance with such request or direction; 
  
 (f) the Trustee shall not be bound to make any investigation
into the facts or matters stated in any resolution, certificate, statement, instrument, opinion, report, notice, request, direction, consent, order, bond, debenture, note, other evidence of indebtedness or other paper or document, but the Trustee,
in its discretion, may make such further inquiry or investigation into such facts or matters as it may see fit; and, if the Trustee shall determine to 

  

 31 

 
make such further inquiry or investigation, it shall be entitled to examine the books, records and premises of the Company, personally or by agent or
attorney at the sole cost of the Company and shall incur no liability or additional liability of any kind by reason of such inquiry or investigation; 
  
 (g) the Trustee may execute any of the trusts or powers hereunder or perform any duties hereunder either directly or by or through agents
or attorneys and the Trustee shall not be responsible for any misconduct or negligence on the part of any agent or attorney appointed with due care by it hereunder; 
  
 (h) the Trustee shall not be charged with knowledge of any Default or Event of Default with respect to the
Securities unless either (i) a Responsible Officer shall have actual knowledge of such Default or Event of Default or (ii) written notice of such Default or Event of Default shall have been received by the Trustee from the Company or any other
obligor on such Securities or by any Holder of such Securities; 
  
 (i) the Trustee shall not be liable for any action taken, suffered or omitted by it in good faith and reasonably believed by it to be authorized or within the discretion or rights or powers conferred upon it by this
Indenture; 
  
 (j) the rights, privileges,
protections, immunities and benefits given to the Trustee, including, without limitation, its right to be indemnified, are extended to, and shall be enforceable by, the Trustee in each of its capacities hereunder, and each agent, custodian,
director, officer, employee and other Person employed to act hereunder; 
  
 (k) the Trustee may request that the Company deliver an Officers’ Certificate setting forth the names of individuals and/or titles of officers authorized at such time to take specified actions pursuant to this
Indenture, which Officers’ Certificate may be signed by any person authorized to sign an Officers’ Certificate, including any person specified as so authorized in any such certificate previously delivered and not superseded; and

  
 (l) the permissive rights of the Trustee to
take certain actions under this Indenture shall not be construed as a duty unless so specified herein. 
  
 Section 6.04. Not Responsible for Recitals. The recitals contained herein and in the Securities, except the Trustee’s certificates of
authentication, shall be taken as the statements of the Company, and the Trustee assumes no responsibility for their correctness. The Trustee makes no representations as to the validity, sufficiency or priority of this Indenture or of the
Securities. The Trustee shall not be accountable for the use or application by the Company of Securities or the proceeds thereof. 
  
 Section 6.05. May Hold Securities. The Trustee, any Paying Agent, any Security Registrar or any other agent of the Company, in its individual or
any other capacity, may become the owner or pledgee of Securities and, subject to Section 6.08 and 6.13, may otherwise deal with 

  

 32 

 
the Company with the same rights it would have if it were not Trustee, Paying Agent, Security Registrar or such other agent. 
  
 Section 6.06. Money Held in Trust. Money held by the Trustee in trust
hereunder need not be segregated from other funds except to the extent required by law. The Trustee shall be under no liability for interest on any money received by it hereunder except as otherwise agreed in writing with the Company. 
  
 Section 6.07. Compensation and Reimbursement. The Company agrees:

  
 (i) to pay to the Trustee from time to time
such compensation for all services rendered by it hereunder as the Company and the Trustee shall from time to time agree in writing (which compensation shall not be limited by any provision of law in regard to the compensation of a trustee of an
express trust); 
  
 (ii) except as otherwise
expressly provided herein, to reimburse the Trustee upon its request for all reasonable expenses, disbursements and advances incurred or made by the Trustee in accordance with any provision of this Indenture (including the reasonable compensation
and the expenses and disbursements of its agents and counsel), except any such expense, disbursement or advance as may be attributable to its negligence or willful misconduct; and 
  
 (iii) to indemnify the Trustee and any predecessor Trustee for, and to hold it harmless against, any loss,
liability or expense including taxes (other than taxes based upon, measured by or determined by the income of the Trustee) incurred without negligence or willful misconduct on its part, arising out of or in connection with the acceptance or
administration of this trust, including the reasonable costs and expenses of defending itself against any claim (whether assessed by the Company, by any Holder or any other Person) or liability in connection with the exercise or performance of any
of its powers or duties hereunder. 
  
 The obligations of the
Company under this Section 6.07 shall survive the resignation or removal of the Trustee and the satisfaction and discharge of this Indenture. To secure the Company’s payment obligations in this Section 6.07, the Trustee shall have a lien prior
to the Securities on all money or property held or collected by the Trustee, except for the Pledged Securities and the money or property held in trust to pay principal, interest and Liquidated Damages, if any, on the Securities. Such lien shall
survive the resignation or removal of the Trustee and the satisfaction and discharge of this Indenture. When the Trustee incurs expenses or renders services after a Default or an Event of Default specified in clauses (g) or (h) of Section 5.01
occurs, the expenses and the compensation for the services (including the fees and expenses of its agents and counsel) are intended to constitute expenses of administration under Title 11 of the U.S. Code or any other similar foreign, federal or
state law for the relief of debtors. 
  

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 Section 6.08. Disqualification; Conflicting Interests. If the Trustee has or shall acquire a
conflicting interest within the meaning of the Trust Indenture Act, the Trustee shall either eliminate such interest or resign, to the extent and in the manner provided by, and subject to the provisions of, the Trust Indenture Act and this
Indenture. 
  
 Section 6.09. Corporate Trustee Required;
Eligibility. There shall at all times be a Trustee hereunder which shall be a Person that is eligible pursuant to the Trust Indenture Act to act as such and has, or whose parent banking company has, a combined capital and surplus of at least
$50,000,000. If such Person publishes reports of condition at least annually, pursuant to law or to the requirements of said supervising or examining authority, then for the purposes of this Section 6.09, the combined capital and surplus of such
Person shall be deemed to be its combined capital and surplus as set forth in its most recent report of condition so published. If at any time the Trustee shall cease to be eligible in accordance with the provisions of this Section 6.09, it shall
resign immediately in the manner and with the effect hereinafter specified in this Article. 
  
 Section 6.10. Resignation and Removal; Appointment of Successor. (a) No resignation or removal of the Trustee and no appointment of a successor Trustee pursuant to this Article 6 shall become effective until
the acceptance of appointment by the successor Trustee under Section 6.11. 
  
 (b) The Trustee may resign at any time by giving written notice thereof to the Company. If an instrument of acceptance by a successor Trustee shall not have been delivered to the Trustee within 30 days after the
giving of such notice of resignation, the resigning Trustee may petition any court of competent jurisdiction at the expense of the Trustee for the appointment of a successor Trustee. 
  
 (c) The Trustee may be removed at any time by Act of the Holders of majority in Principal Amount of the
Outstanding Securities, delivered to the Trustee and to the Company. If an instrument of acceptance by a successor Trustee shall not have been delivered to the Trustee within 30 days after the notice of removal, the Trustee being removed may
petition, at the expense of the Company, any court of competent jurisdiction for the appointment of a successor Trustee with respect to the Securities. 
  
 (d) If at any time: 
  
 (i) the Trustee shall fail to comply with Section 6.08 after written request therefor by the Company or by any Holder who has been a bona
fide Holder of a Security for at least six months, or 
  
 (ii) the Trustee shall cease to be eligible under Section 6.09 and shall fail to resign after written request therefor by the Company or by any such Holder, or 
  

 34 

 (iii) the Trustee shall become incapable of acting or shall be adjudged a bankrupt or
insolvent, or 
  
 (iv) a receiver of the Trustee
or of its property shall be appointed or any public officer shall take charge or control of the Trustee or of its property or affairs for the purpose of rehabilitation, conservation or liquidation, 
  
 then, in any such case, (A) the Company by a Company Order may remove the Trustee, or (B)
subject to Section 5.13, any Holder who has been a bona fide Holder of a Security for at least six months may, on behalf of such Holder and all others similarly situated, petition any court of competent jurisdiction for the removal of the Trustee
and the appointment of a successor Trustee. 
  
 (e) If the Trustee shall resign, be removed or become incapable of acting, or if a vacancy shall occur in the office of Trustee for any cause, the Company, by a Company Order, shall promptly appoint a successor Trustee. If, within one year
after such resignation, removal or incapability, or the occurrence of such vacancy, a successor Trustee shall be appointed by Act of the Holders of a majority in Principal Amount of the Outstanding Securities delivered to the Company and the
retiring Trustee, the successor Trustee so appointed shall, forthwith upon its acceptance of such appointment, become the successor Trustee and supersede the successor Trustee appointed by the Company. If no successor Trustee shall have been so
appointed by the Company or the Holders and accepted appointment in the manner hereinafter provided, any Holder who has been a bona fide Holder of a Security for at least six months may, on behalf of himself and all others similarly situated,
petition any court of competent jurisdiction for the appointment of a successor Trustee. 
  
 (f) The Company shall give notice of each resignation and each removal of the Trustee and each appointment of a successor Trustee to all
Holders in the manner provided in Section 1.06. Each notice shall include the name of the successor Trustee and the address of its Corporate Trust Office. 
  
 Section 6.11. Acceptance of Appointment by Successor. Every successor Trustee appointed hereunder shall execute, acknowledge and deliver to the
Company and to the retiring Trustee an instrument accepting such appointment, and thereupon the resignation or removal of the retiring Trustee shall become effective and such successor Trustee, without any further act, deed or conveyance, shall
become vested with all the rights, powers, trusts and duties of the retiring Trustee; but, on request of the Company or the successor Trustee, such retiring Trustee shall, upon payment of its charges, execute and deliver an instrument transferring
to such successor Trustee all the rights, powers and trusts of the retiring Trustee and shall duly assign, transfer and deliver to such successor Trustee all property and money held by such retiring Trustee hereunder. Upon request of any such
successor Trustee, the Company shall execute any and all instruments for more fully and certainly vesting in and confirming to such successor Trustee all such rights, powers and trusts. 
  
 No successor Trustee shall accept its appointment unless at the time of such acceptance such successor Trustee shall be
qualified and eligible under this Article 6. 
  

 35 

 Notwithstanding the resignation or removal of the Trustee, the Company’s obligations under Section
6.07 shall continue for the benefit of the retiring trustee with respect to expenses and liabilities incurred by it prior to such resignation or removal. 
  
 Section 6.12. Merger, Conversion, Consolidation or Succession to Business. Any corporation into which the Trustee may be merged or converted or
with which it may be consolidated, or any corporation resulting from any merger, conversion or consolidation to which the Trustee shall be a party, or any corporation succeeding to all or substantially all the corporate trust business of the Trustee
by sale or otherwise, shall be the successor of the Trustee hereunder, provided such corporation shall be otherwise qualified and eligible under this Article 6, without the execution or filing of any paper or any further act on the part of any of
the parties hereto. In case any Securities shall have been authenticated, but not delivered, by the Trustee then in office, any successor by merger, conversion or consolidation to such authenticating Trustee may adopt such authentication and deliver
the Securities so authenticated with the same effect as if such successor Trustee had itself authenticated such Securities. 
  
 Section 6.13. Preferential Collection of Claims Against. If and when the Trustee shall be or become a creditor of the Company (or any other obligor
upon the Securities), the Trustee shall be subject to the provisions of the Trust Indenture Act regarding the collection of claims against the Company (or any such other obligor). 
  
 ARTICLE 7 
 Holders’ Lists And Reports By Trustee 
  
 Section
7.01. Company to Furnish Trustee Names and Addresses of Holders. The Company will furnish or cause to be furnished to the Trustee: 
  
 (i) semi-annually, not more than 15 days after each Record Date, a list, in such form as the Trustee may reasonably require, of the names
and addresses of the Holders as of such Record Date; and 
  
 (ii) at such other times as the Trustee may request in writing, within 30 days after the receipt by the Company of any such request, a list of similar form and content as of a date not more than 15 days prior to the
time such list is furnished; 
  
 excluding from any such list names and addresses
received by the Trustee in its capacity as Security Registrar; provided, however, that no such list need be furnished so long as the Trustee is acting as Security Registrar. 
  
 Section 7.02. Preservation of Information; Communications to Holders. (a) The Trustee shall preserve, in as current a
form as is reasonably practicable, the names and addresses of Holders contained in the most recent list furnished to the Trustee as provided in Section 7.01 and the names and addresses of Holders received by the Trustee in its capacity as Security

  

 36 

 
Registrar. The Trustee may destroy any list furnished to it as provided in Section 7.01 upon receipt of a new list so furnished. 
  
 (b) The rights of Holders to communicate with other Holders
with respect to their rights under this Indenture or under the Securities, and the corresponding rights and duties of the Trustee, shall be as provided by the Trust Indenture Act. 
  
 (c) Every Holder of Securities, by receiving and holding the same, agrees with the Company and the Trustee
that neither the Company nor the Trustee nor any agent of either of them shall be held accountable by reason of any disclosure of information as to names and addresses of Holders made pursuant to the Trust Indenture Act. 
  
 Section 7.03. Reports By Trustee. (a) The Trustee shall transmit to
Holders such reports concerning the Trustee and its actions under this Indenture as may be required pursuant to the Trust Indenture Act at the times and in the manner provided pursuant thereto. Reports so required to be transmitted at stated
intervals of not more than 12 months shall be transmitted no later than July 15 in each calendar year, commencing in July 15, 2004. Each such report shall be dated as of a date not more than 60 days prior to the date of transmission. 
  
 (b) A copy of each such report shall, at the time of such
transmission to Holders, be filed by the Trustee with each stock exchange, if any, upon which the Securities are listed, with the Commission and with the Company. The Company will notify the Trustee when the Securities are listed on any stock
exchange or of any delisting thereof. 
  
 Section 7.04. Reports
by Company. The Company shall file with the Trustee and the Commission, and transmit to Holders, such information, documents and other reports, and such summaries thereof, as may be required pursuant to the Trust Indenture Act at the times and
in the manner provided pursuant to such Act; provided that any such information, documents or reports required to be filed with the Commission pursuant to Section 13 or 15(d) of the Exchange Act shall be filed with the Trustee within 15 days after
the same is so required to be filed with the Commission. In the event the Company is not subject to Section 13 or 15(d) of the Exchange Act, it shall file with the Trustee upon request the information required to be delivered pursuant to Rule
144A(d)(4) under the Securities Act. It is expressly understood that materials transmitted electronically by the Company to the Trustee shall be deemed filed with the Trustee for purposes of this Section 7.04. The Trustee shall not be under a duty
to review or evaluate any report or information delivered to the Trustee pursuant to the provisions of this Section 7.04 for the purposes of making such reports available to it and to the Holders of Securities who may request such information.
Delivery of such reports, information and documents to the Trustee as may be required under this Section 7.04 is for informational purposes only and the Trustee’s receipt of such shall not constitute constructive notice of any information
contained therein or determinable from information contained therein, including the Company’s compliance with any of its covenants hereunder (as to which the Trustee is entitled to rely exclusively on an Officers’ Certificate). 

 

 37 

 ARTICLE 8 
 Consolidation, Merger, Conveyance, Transfer Or Lease 
  
 Section 8.01. Company May Consolidate, etc., Only on Certain Terms. The Company shall not consolidate with or merge into any other Person or convey, transfer or lease its properties and assets substantially as
an entirety to any Person, and the Company shall not permit any Person to consolidate with or merge into the Company or convey, transfer or lease its properties and assets substantially as an entirety to the Company, unless: 
  
 (a) either (i) the Company shall be the continuing Person or
(ii) the Person (if other than the Company) formed by such consolidation or into which the Company is merged or the Person which acquires by conveyance or transfer, or which leases, the properties and assets of the Company substantially as an
entirety (the “Surviving Entity”), (1) shall be either (a) organized and validly existing under the laws of the United States of America, any State thereof or the District of Columbia, or (b) organized under the laws of a
jurisdiction outside the United States and has common stock traded on a national securities exchange in the United States and a worldwide total market capitalization of its equity securities before giving effect to the consolidation or merger of at
least US$2 billion, and (2) the Surviving Entity shall expressly assume, by an indenture supplemental hereto, executed and delivered to the Trustee, all of the obligations of the Company under the Securities and this Indenture; 
  
 (b) immediately after giving effect to such transaction, no
Event of Default, and no event which, after notice or lapse of time or both, would become an Event of Default, shall have occurred and be continuing; and 
  
 (c) the Company or the Surviving Entity has delivered to the Trustee an Officers’ Certificate and an Opinion of Counsel, each stating
that such consolidation, merger, conveyance, transfer or lease and, if a supplemental indenture is required in connection with such transaction, such supplemental indenture comply with this Article 8 and Article 9, respectively. 
  
 Section 8.02. Successor Substituted. Upon any consolidation of the
Company with, or merger of the Company into, any other Person or any conveyance, transfer or lease of the properties and assets of the Company substantially as an entirety in accordance with Section 8.01, the successor Person formed by such
consolidation or into which the Company is merged or to which such conveyance, transfer or lease is made shall succeed to, and be substituted for, and may exercise every right and power of, the Company under this Indenture with the same effect as if
such successor Person had been named as the Company herein, and thereafter, except in the case of a lease, the predecessor Person shall be relieved of all obligations and covenants under this Indenture and the Securities. 
  
 ARTICLE 9 
 Supplemental Indentures 
  
 Section 9.01. Supplemental Indentures Without Consent of Holders. Without the consent of any Holders, the Company, when authorized by a Board Resolution, and the Trustee, 

  

 38 

 
at any time and from time to time, may enter into one or more indentures supplemental hereto, in form satisfactory to the Trustee, for any of the following
purposes: 
  
 (i) to evidence the succession of
another Person to the Company and the assumption by any such successor of the covenants of the Company herein and in the Securities; or 
  
 (ii) to add to the covenants of the Company for the benefit of the Holders, or to surrender any right or power herein conferred upon the
Company; or 
  
 (iii) to provide for a successor
Trustee with respect to the Securities; or 
  
 (iv) to cure any ambiguity or defect, to correct or supplement any provision herein which may be inconsistent with any other provision herein, or to make any other provisions with respect to matters or questions arising under this Indenture
which shall not be inconsistent with the provisions of this Indenture; provided that such action pursuant to this clause (iv) shall not adversely affect the interests of the Holders in any material respect; or 
  
 (v) to add any additional Events of Default for the benefit
of the Holders; or 
  
 (vi) to convey, transfer,
assign, mortgage or pledge to the Trustee as security for the Securities any property or assets; or 
  
 (vii) to increase the Conversion Rate of the Securities; provided, however, that such increase shall be in accordance with the terms of
this Indenture or shall not adversely affect the interests of the Holders of the Securities; or 
  
 (viii) to supplement any provision of this Indenture to such extent as shall be necessary to permit or facilitate the discharge of the
Securities; provided that such change or modification does not adversely affect the interests of the Holders of the Securities; or 
  
 (ix) to make any change or modification necessary in connection with the registration of the Securities under the Securities Act as
contemplated in the Registration Rights Agreement; provided that such change or modification does not adversely affect the interests of the Holders of Securities; or 
  
 (x) to add or modify any other provision herein with respect to matters or questions arising hereunder which
the Company and the Trustee may deem necessary or desirable and which would not reasonably be expected to adversely affect the interests of the Holders of Securities in any material respect. 
  

 39 

 Section 9.02. Supplemental Indentures With Consent of Holders. With the consent of the Holders of
not less than a majority in Principal Amount of the Outstanding Securities, by Act of said Holders delivered to the Company and the Trustee, the Company, when authorized by a Board Resolution, and the Trustee may enter into an indenture or
indentures supplemental hereto for the purpose of adding any provisions to or changing in any manner or eliminating any of the provisions of this Indenture or of modifying in any manner the rights of the Holders under this Indenture; provided,
however, that no such supplemental indenture shall, without the consent of the Holder of each Outstanding Security affected thereby, 
  
 (i) reduce the rate of or extend the time for payment of interest, if any, on the Security; or 
  
 (ii) reduce the Principal Amount of, or extend the Stated
Maturity of, any Security; or 
  
 (iii) make any
change that impairs or adversely affects the conversion rights of any Securities; or 
  
 (iv) reduce the Redemption Price, the Repurchase Price or Fundamental Change Repurchase Price of any Security or amend or modify in any
manner adverse to the Holders of Securities the Company’s obligation to make such payments, whether through an amendment or waiver of provisions in the covenants, definitions or otherwise; or 
  
 (v) modify the provisions with respect to the right of
Holders to cause the Company to repurchase Securities upon a Fundamental Change in a manner adverse to Holders of Securities; or 
  
 (vi) make any interest or principal on a Security payable in money other than that stated in the Security or other than in accordance with
the provisions of this Indenture; or 
  
 (vii)
impair the right of any Holder to receive payment of the Principal Amount of or interest or Liquidated Damages, if any, on a Holder’s Securities on or after the due dates therefor or to institute suit for the enforcement of any payment on or
with respect to such Holder’s Securities; or 
  
 (viii) reduce the quorum or voting requirements under this Indenture; or 
  
 (ix) change the ranking of the Securities in a manner adverse to the Holders of the Securities; or 
  
 (x) make any change in the amendment provisions which
require each Holder’s consent or in the waiver provisions; or 
  

 40 

 (xi) reduce the percentage in Principal Amount of the Outstanding Securities, the consent
of whose Holders is required for any such supplemental indenture, or the consent of whose Holders is required for any waiver (of compliance with certain provisions of this Indenture or certain defaults hereunder and their consequences) provided for
in this Indenture; or 
  
 (xii) modify any of the
provisions of this Section 9.02 or Section 5.12, except to increase any such percentage or to provide that certain other provisions of this Indenture cannot be modified or waived without the consent of the Holder of each Outstanding Security
affected thereby; or 
  
 (xiii) modify the
provisions of the Indenture or the Pledge Agreement relating to the Pledged Securities in a manner adverse to the Holders in any material respect. 
  
 It shall not be necessary for any Act of Holders under this Section 9.02 to approve the particular form of any proposed supplemental indenture, but it
shall be sufficient if such Act shall approve the substance thereof. 
  
 Section 9.03. Execution of Supplemental Indentures. In executing, or accepting the additional trusts created by, any supplemental indenture permitted by this Article 9 or the modifications thereby of the trusts created by this
Indenture, the Trustee shall be provided with, and (subject to Section 6.01) shall be fully protected in relying upon, in addition to the documents required by Section 1.02, an Opinion of Counsel stating that the execution of such supplemental
indenture is authorized or permitted by this Indenture. Subject to the preceding sentence, the Trustee shall sign such supplemental indenture if the same does not adversely affect the Trustee’s own rights, duties or immunities under this
Indenture or otherwise. The Trustee may, but shall not be obligated to, enter into any such supplemental indenture that adversely affects the Trustee’s own rights, duties or immunities under this Indenture or otherwise. 
  
 Section 9.04. Effect of Supplemental Indentures. Upon the execution of
any supplemental indenture under this Article 9, this Indenture shall be modified in accordance therewith, and such supplemental indenture shall form a part of this Indenture for all purposes; and every Holder of Securities theretofore or thereafter
authenticated and delivered hereunder shall be bound thereby. 
  
 Section 9.05. Conformity with Trust Indenture Act. Every supplemental indenture executed pursuant to this Article shall conform to the requirements of the Trust Indenture Act. 
  
 Section 9.06. Reference in Securities to Supplemental Indentures.
Securities authenticated and delivered after the execution of any supplemental indenture pursuant to this Article 9 shall bear a notation in form approved by the Trustee as to any matter provided for in such supplemental indenture. If the Company
shall so determine, new Securities so modified as to conform, in the opinion of the Trustee and the Company, to any such supplemental indenture 

  

 41 

 
may be prepared and executed by the Company and authenticated and delivered by the Trustee in exchange for Outstanding Securities. 
  
 ARTICLE 10 
 Covenants 
  
 Section 10.01. Payments. The Company shall duly and punctually make all payments in respect of the Securities in accordance with the terms of the Securities and this Indenture. 
  
 Any payments made or due pursuant to this Indenture shall be considered paid
on the applicable date due if by 10:00 a.m., New York City time, on such date the Paying Agent holds, in accordance with this Indenture, cash sufficient to pay all such amounts then due. Payment of the principal, interest and Liquidated Damages, if
any, on the Securities shall be in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private debts. 
  
 Section 10.02. Maintenance of Office or Agency. The Company shall maintain in the Borough of Manhattan, The City of
New York, an office or agency where Securities may be presented or surrendered for payment, where Securities may be surrendered for registration of transfer or exchange and where notices and demands to or upon the Company in respect of the
Securities and this Indenture may be served, which shall initially be the Corporate Trust Office of the Trustee. The Company shall give prompt written notice to the Trustee of any change in the location, of such office or agency. If at any time the
Company shall fail to maintain any such required office or agency or shall fail to furnish the Trustee with the address thereof, such presentations, surrenders, notices and demands may be made or served at the Corporate Trust Office of the Trustee,
and the Company hereby appoints the Trustee as its agent to receive all such presentations, surrenders, notices and demands. 
  
 The Company may also from time to time designate one or more other offices or agencies (in or outside the Borough of Manhattan, The City of New York)
where the Securities may be presented or surrendered for any or all such purposes and may from time to time rescind such designations; provided, however, that no such designation or rescission shall in any manner relieve the Company of its
obligation to maintain an office or agency in the Borough of Manhattan, The City of New York, for such purposes. The Company shall give prompt written notice to the Trustee of any such designation or rescission and of any change in the location of
any such other office or agency. The Company hereby initially designates U.S. Bank National Association, U.S. Bank Trust New York, 100 Wall Street, Suite 1600, New York, NY 10005 as one such office or agency of the Company. 
  
 Section 10.03. Money for Security Payments to be Held in Trust. If the
Company shall at any time act as its own Paying Agent, it shall, on or before each due date of any payment in respect of any of the Securities, segregate and hold in trust for the benefit of the Persons entitled thereto a sum sufficient to make the
payment so becoming due until such sums shall be paid to such Persons or otherwise disposed of as herein provided and shall promptly notify the Trustee of its action or failure so to act. 
  

 42 

 Whenever the Company shall have one or more Paying Agents, it will, prior to each due date of any payment
in respect of any Securities, deposit with a Paying Agent a sum sufficient to pay such amount, such sum to be held as provided by the Trust Indenture Act, and (unless such Paying Agent is the Trustee) the Company will promptly notify the Trustee of
its action or failure so to act. 
  
 The Company shall cause each
Paying Agent other than the Trustee to execute and deliver to the Trustee an instrument in which such Paying Agent shall agree with the Trustee, subject to the provisions of this Section 10.03, that such Paying Agent will (i) comply with the
provisions of the Trust Indenture Act applicable to it as a Paying Agent and (ii) during the continuance of any default by the Company (or any other obligor upon the Securities) in the making of any payment in respect of the Securities, upon the
written request of the Trustee, forthwith pay to the Trustee all sums held in trust by such Paying Agent as such. 
  
 The Company may at any time, for the purpose of obtaining the satisfaction and discharge of this Indenture or for any other purpose, pay, or by Company
Order direct any Paying Agent to pay, to the Trustee all sums held in trust by the Company or such Paying Agent, such sums to be held by the Trustee upon the same trusts as those upon which such sums were held by the Company or such Paying Agent;
and, upon such payment by any Paying Agent to the Trustee, such Paying Agent shall be released from all further liability with respect to such money. 
  
 Any money deposited with the Trustee or any Paying Agent, or then held by the Company, in trust for the making of payments in respect of any Security and
remaining unclaimed for two years after such payment has become due shall be paid to the Company on Company Request, or (if then held by the Company) shall be discharged from such trust; and the Holder of such Security shall thereafter, as an
unsecured general creditor, look only to the Company for payment thereof, and all liability of the Trustee or such Paying Agent with respect to such trust money, and all liability of the Company as trustee thereof, shall thereupon cease; provided,
however, that the Trustee or such Paying Agent, before being required to make any such repayment, may at the expense of the Company cause to be published once, in a newspaper published in the English language, customarily published on each Business
Day and of general circulation in The City of New York, notice that such money remains unclaimed and that, after a date specified therein, which shall not be less than 30 days from the date of such publication, any unclaimed balance of such money
then remaining shall be repaid to the Company. In the absence of a written request from the Company to return funds remaining unclaimed for two years after such payment has become due to the Company, the Trustee shall from time to time deliver all
unclaimed payments to or as directed by applicable escheat authorities, as determined by the Trustee in its sole discretion, in accordance with the customary practices and procedures of the Trustee. Any such unclaimed funds held by the Trustee
pursuant to this Section 10.03 shall be held uninvested and without any liability for interest. 
  
 Section 10.04. Statement by Officers as to Default. The Company will deliver to the Trustee, within 120 days after the end of each fiscal year of
the Company ending after the date 

  

 43 

 
hereof, an Officers’ Certificate, stating whether or not to the knowledge of the signers thereof the Company is in Default in the performance and
observance of any of the terms, provisions and conditions of this Indenture (without regard to any period of grace or requirement of notice provided hereunder) and, if the Company shall be in Default, specifying all such Defaults and the nature and
status thereof of which they may have knowledge. 
  
 The Company
shall deliver to the Trustee, as soon as possible and in any event within 30 days after the Company becomes aware of the occurrence of any Event of Default or an event which, with notice or the lapse of time or both, would constitute an Event of
Default, an Officers’ Certificate setting forth the details of such Event of Default or default and the action which the Company is taking or proposes to take with respect thereto. 
  
 Section 10.05. Existence. Subject to Article 8, the Company shall do or cause to be done all things necessary to
preserve and keep in full force and effect its existence, rights (charter and statutory) and franchises; provided, however, that the Company shall not be required to preserve any such right or franchise if the Board of Directors of the Company shall
determine that the preservation thereof is no longer desirable in the conduct of the business of the Company and that the loss thereof is not disadvantageous in any material respect to the Holders. 
  
 Section 10.06. Reports and Delivery of Certain Information. Whether or
not required by the rules and regulations of the Commission, so long as any Securities are outstanding, the Company shall promptly furnish to the Trustee (i) all quarterly and annual financial information that is substantially equivalent to that
which would be required to be contained in a filing with the Commission on Forms 10-Q and 10-K if the Company were required to file such Forms, including a “Management’s Discussion and Analysis of Financial Condition and Results of
Operations” section and, with respect to the annual information only, a report thereon by the Company’s certified independent accountants and (ii) all reports that are substantially equivalent to that which would be required to be filed
with the Commission on Form 8-K if the Company were required to file such reports; provided that in each case the delivery of materials to the Trustee by electronic means shall be deemed to be “furnished” to the Trustee for purposes of
this Section 10.06. In addition, whether or not required by the rules and regulations of the Commission, the Company shall file a copy of all such information with the Commission for public availability (unless the Commission will not accept such a
filing) and make such information available to investors who request it in writing. So long as any of the Securities remain Outstanding, the Company shall make available to any prospective purchaser of Securities or beneficial owner of Securities in
connection with any sale thereof the information required by Rule 144A(d)(4) under the Securities Act, until the earlier of (a) such time as the Holders thereof have disposed of such Securities pursuant to an effective Resale Registration Statement
or Rule 144 under the Securities Act and (b) the date that is two years from the Issue Date. 
  
 Section 10.07. Resale of Certain Securities. During the period beginning on the Issue Date and ending on the date that is two years from the Issue Date, the Company shall not, and shall not permit any of its
“affiliates” (as defined under Rule 144 under the Securities Act or any 

  

 44 

 
successor provision thereto) to, resell any Securities which constitute “restricted securities” under Rule 144 that have been reacquired by
any of them. The Trustee shall have no responsibility in respect of the Company’s performance of its agreement in the preceding sentence. 
  
 Section 10.08. Book-Entry System. If the Securities cease to trade in the Depositary’s book-entry settlement system, the Company covenants and
agrees that it shall use reasonable efforts to make such other book entry arrangements that it determines are reasonable for the Securities. 
  
 Section 10.09. Liquidated Damages Under the Registration Rights Agreement. If at any time Liquidated Damages become payable by the Company pursuant
to the Registration Rights Agreement, the Company shall promptly deliver to the Trustee a certificate to that effect and stating (i) the amount of such Liquidated Damages that are payable and (ii) the date on which such Liquidated Damages are
payable pursuant to the terms of the Registration Rights Agreement. Unless and until a Responsible Officer of the Trustee receives such a certificate, the Trustee may assume without inquiry that no Liquidated Damages are payable. If the Company has
paid Liquidated Damages directly to the Persons entitled to such Liquidated Damages, the Company shall deliver to the Trustee a certificate setting forth the particulars of such payment. 
  
 Section 10.10. Information for IRS Filings. The Company shall provide to the Trustee on a timely basis such
information as the Trustee requires to enable the Trustee to prepare and file any form required to be submitted by the Company with the Internal Revenue Service and the Holders of the Securities. 
  
 ARTICLE 11 
 Redemption And Repurchase Upon A Fundamental Change 
  
 Section 11.01. Right to Redeem; Notices to Trustee. Prior to May 10, 2010, the Securities are not redeemable. At any time commencing on May 10,
2010, the Securities are redeemable as a whole, or from time to time in part, at the option of the Company at the Redemption Price equal to 100% expressed as a percentage of the Principal Amount of Securities to be redeemed, together with accrued
and unpaid interest and Liquidated Damages, if any, to, but excluding, the Redemption Date. 
  
 The Company shall give the notice to the Trustee provided for in this Section 11.01 by a Company Order, at least 30 days but not more than 60 days before the Redemption Date (unless a shorter notice shall be
satisfactory to the Trustee). 
  
 Section 11.02. Selection of
Securities to be Redeemed. If less than all the Securities are to be redeemed, the Trustee shall select the Securities to be redeemed pro rata or by lot or by any other method the Trustee considers fair and appropriate (so long as such method is
not prohibited by the rules of any stock exchange on which the Securities are then listed). The Trustee shall make the selection within seven days from its receipt of the notice from the Company delivered 

  

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pursuant to the second paragraph of Section 11.01 from Outstanding Securities not previously called for redemption. 
  
 Securities and portions of them the Trustee selects shall be in Principal
Amounts of $1,000 or integral multiples of $1,000. Provisions of this Indenture that apply to Securities called for redemption in whole also apply to Securities called for redemption in part. The Trustee shall notify the Company promptly of the
Securities or portions of Securities to be redeemed. 
  
 If any
Security selected for partial redemption is converted in part before termination of the conversion right with respect to the portion of the Security so selected, the converted portion of such Security shall be deemed (so far as may be) to be the
portion selected for redemption. Securities which have been converted during a selection of Securities to be redeemed may be treated by the Trustee as outstanding for the purpose of such selection. 
  
 Section 11.03. Notice of Redemption. At least 30 days but not more
than 60 days before a Redemption Date, the Company shall mail a notice of redemption by first-class mail, postage prepaid, to each Holder of Securities to be redeemed. 
  
 The notice shall identify the Securities to be redeemed and shall state: 
  
 (i) the Redemption Date; 
  
 (ii) the Redemption Price; 
  
 (iii) the Conversion Price; 
  
 (iv) the name and address of the Paying Agent and Conversion
Agent; 
  
 (v) that Securities called for
redemption may be converted at any time before the close of business on the Business Day immediately preceding the Redemption Date; 
  
 (vi) that Holders who want to convert Securities must satisfy the requirements set forth therein and in this Indenture; 
  
 (vii) that Securities called for redemption must be
surrendered to the Paying Agent for cancellation to collect the Redemption Price; 
  
 (viii) if fewer than all the outstanding Securities are to be redeemed, the certificate number (if such Securities are held other than in
global form) and Principal Amounts of the particular Securities to be redeemed; 
  
 (ix) that, unless the Company defaults in making payment of such Redemption Price, interest and Liquidated Damages, if any, will cease to

  

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accrue on and after the Redemption Date with respect to the Securities to be redeemed; and 
  
 (x) the CUSIP number of the Securities. 
  
 At the Company’s written request delivered at least 15 days prior to the date such notice is to be given (unless a
shorter time period shall be acceptable to the Trustee), the Trustee shall give the notice of redemption in the Company’s name and at the Company’s expense. 
  
 Section 11.04. Effect of Notice of Redemption. Once notice of redemption is given, Securities called for redemption
become due and payable on the Redemption Date and at the Redemption Price stated in the notice except for Securities which are converted in accordance with the terms of this Indenture. Upon surrender to the Paying Agent, such Securities shall be
paid at the Redemption Price stated in the notice. 
  
 Section
11.05. Deposit of Redemption Price. Prior to 10:00 a.m. (New York City time) on a Redemption Date, the Company shall deposit with the Paying Agent (or if the Company or a Subsidiary or an Affiliate of either of them is the Paying Agent, shall
segregate and hold in trust) money sufficient to pay the Redemption Price of all Securities to be redeemed on that date other than Securities or portions of Securities called for redemption which on or prior thereto have been delivered by the
Company to the Trustee for cancellation or have been converted. The Paying Agent shall as promptly as practicable return to the Company any money not required for that purpose because of conversion of Securities pursuant to Article 13. If such money
is then held by the Company in trust and is not required for such purpose it shall be discharged from such trust. 
  
 Section 11.06. Securities Redeemed in Part. Upon surrender of a Security that is redeemed in part, the Company shall execute and the Trustee shall
authenticate and deliver to the Holder a new Security in an authorized denomination equal in principal amount to the unredeemed portion of the Security surrendered. The Company shall not be required to (i) issue, register the transfer of, or
exchange any Securities during a period of 15 days before the Redemption Date or (ii) register the transfer of, or exchange any, Securities so selected for redemption, in whole or in part, except the unredeemed portion of any Security being redeemed
in part. 
  
 Section 11.07. Conversion Arrangement on Call for
Redemption. In connection with any redemption of Securities, the Company may arrange for the purchase and conversion of any Securities called for redemption by an agreement with one or more investment bankers or other purchasers to purchase such
Securities by paying to the Trustee in trust for the Securityholders, on or prior to 10:00 a.m. New York City time on the Redemption Date, an amount that, together with any amounts deposited with the Trustee by the Company for the redemption of such
Securities, is not less than the Redemption Price of such Securities. Notwithstanding anything to the contrary contained in this Article 11, the obligation of the Company to pay the Redemption Price of such Securities shall be deemed to be satisfied
and discharged to the extent such amount is so paid by such purchasers. If such an agreement is entered into, any Securities not duly 

  

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surrendered for conversion by the Holders thereof may, at the option of the Company, be deemed, to the fullest extent permitted by law, acquired by such
purchasers from such Holders and (notwithstanding anything to the contrary contained in Article 13) surrendered by such purchasers for conversion, all as of immediately prior to the close of business on the Business Day prior to the Redemption Date,
subject to payment of the above amount as aforesaid. The Trustee shall hold and pay to the Holders whose Securities are selected for redemption any such amount paid to it for purchase and conversion in the same manner as it would moneys deposited
with it by the Company for the redemption of Securities. Without the Trustee’s prior written consent, no arrangement between the Company and such purchasers for the purchase and conversion of any Securities shall increase or otherwise affect
any of the powers, duties, responsibilities or obligations of the Trustee as set forth in this Indenture, and the Company agrees to indemnify the Trustee from, and hold it harmless against, any loss, liability or expense arising out of or in
connection with any such arrangement for the purchase and conversion of any Securities between the Company and such purchasers, including the costs and expenses incurred by the Trustee in the defense of any claim or liability arising out of or in
connection with the exercise or performance of any of its powers, duties, responsibilities or obligations under this Indenture, except in the case of the Trustee’s negligence or willful misconduct. 
  
 Section 11.08. Repurchase of Securities at Option of the Holder Upon
Fundamental Change. 
  
 (a) General.
If prior to the Stated Maturity there shall have occurred a Fundamental Change, Securities shall be repurchased by the Company at the Fundamental Change Repurchase Price on a date specified by the Company that is not less than 25 days nor more than
35 days after the date of the mailing of a Fundamental Change Company Notice pursuant to clause (b) of this Section 11.08 (the “Fundamental Change Repurchase Date”), at the option of the Holder thereof, in accordance with the
following procedures; provided that the Company shall not be required to repurchase the Securities pursuant to this Section 11.08 if the Closing Price per share of Common Stock for any five Trading Days within the period of ten consecutive Trading
Days ending immediately after the later of the Fundamental Change and the public announcement of the Fundamental Change equals or exceeds 110% of the Conversion Price of the Securities in effect on each of those five Trading Days. 
  
 (b) Make-Whole Premium. If prior to the Stated
Maturity there shall have occurred a Fundamental Change and all of the consideration for the Common Stock in the transaction or transactions constituting the Fundamental Change consists of cash (a “Cash Buy-Out”), the Company will
pay a Make-Whole Premium to the Holders of the Securities in addition to the Fundamental Change Repurchase Price. 
  
 The “Make-Whole Premium” per Security will equal (a) the average of the Trading Prices of a Security for the five Trading
Days immediately prior to the Company’s public announcement of the Cash Buy-Out, less (b) the greater of (i) $1,000 or (ii) the product of (x) the average Closing Prices of the Common Stock for the five Trading Days immediately 

  

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prior to the Company’s public announcement of the Cash Buy-Out and (y) the applicable Conversion Rate. The Make-Whole Premium, if any, will not be less
than zero. 
  
 The Trustee shall have no duty to
calculate the Make-Whole Premium. The Company shall make the calculations described in this Section 11.08, using the Trading Price provided by the Trustee. The Trustee shall be entitled in its sole discretion to consult with the Company and to
request the assistance of the Company in connection with the Trustee’s duties pursuant to this Section 11.08, and the Company agrees, if requested by the Trustee, to cooperate with, and provide assistance to, the Trustee in carrying out its
duties under this Section 11.08. 
  
 The
Make-Whole Premium may be paid for, at the election of the Company, in cash or shares of Common Stock, provided that the shares of Common Stock will be issued out of the Company’s authorized but unissued Common Stock and will, upon issuance, be
duly and validly issued and fully paid and nonassessable and free of any preemptive or similar rights. 
  
 (c) Company Notice of Fundamental Change. Within 15 days after the Company knows or reasonably should know of the occurrence of a
Fundamental Change, the Company shall, if Holders have the right to require the Company to repurchase Securities hereunder, deliver a written notice of Fundamental Change (the “Fundamental Change Company Notice”) by first-class mail
or by overnight courier to the Trustee and to each Holder (and to beneficial owners as required by applicable law). The notice shall include a form of Fundamental Change Repurchase Notice to be completed by the Securityholder and shall state:

  
 (i) the events causing a Fundamental Change
and the date of such Fundamental Change; 
  
 (ii)
the date by which a Holder must deliver a Fundamental Change Repurchase Notice to elect the repurchase option pursuant to this Section 11.08; 
  
 (iii) the Fundamental Change Repurchase Date; 
  
 (iv) the Fundamental Change Repurchase Price; 
  
 (v) whether the Fundamental Change Repurchase Price will be paid in cash, shares of Common Stock or a combination thereof, specifying the
percentages of each; 
  
 (vi) if shares of Common
Stock will be used to pay all or part of the Fundamental Change Repurchase Price, state: 
  
 (a) the method for valuing the shares of Common Stock to be delivered in connection with the repurchase; and 
  

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 (b) that Holders of the Securities will bear the market risk with respect to the value
of the shares of Common Stock to be delivered from the date the number of shares is determined; 
  
 (vii) the name and address of the Paying Agent and the Conversion Agent; 
  
 (viii) the Conversion Rate applicable on the date of the Fundamental Change Company Notice; 
  
 (ix) that Securities as to which a Fundamental Change
Repurchase Notice has been given may be converted pursuant to Article 13 hereof only if the Fundamental Change Repurchase Notice has been withdrawn in accordance with the terms of this Indenture; 
  
 (x) that Securities must be surrendered to the Paying Agent
for cancellation to collect payment; 
  
 (xi)
that the Fundamental Change Repurchase Price for any Security as to which a Fundamental Change Repurchase Notice has been duly given and not withdrawn will be paid promptly following the later of the Fundamental Change Repurchase Date and the time
of surrender of such Security as described in clause (x) above; 
  
 (xii) the procedures the Holder must follow to exercise rights under this Section 11.08; 
  
 (xiii) the conversion rights of the Securities; 
  

(xiv) the procedures for withdrawing a Fundamental Change Repurchase Notice; 
  
 (xv) that, unless the Company defaults in making payment of
such Fundamental Change Repurchase Price, Securities covered by any Fundamental Change Repurchase Notice will cease to be outstanding and interest and Liquidated Damages, if any, will cease to accrue on and after the Fundamental Change Repurchase
Date; 
  
 (xvi) the CUSIP number of the
Securities; and 
  
 (xvii) whether or a
Make-Whole Premium is required to be paid by the Company and whether such Make-Whole Premium shall be paid in cash or by delivery of shares of Common Stock. 
  

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 At the Company’s request, the Trustee shall give such Fundamental Change Company Notice in the
Company’s name and at the Company’s expense; provided that, in all cases, the text of such Fundamental Change Company Notice shall be prepared by the Company. In connection with delivery of the Fundamental Change Company Notice to the
Holders, the Company shall publish a notice containing substantially the same information that is required in the Fundamental Change Company Notice in a newspaper published in the English language, customarily published each Business Day and of
general circulation in The City of New York, or publish such information on the Company’s website or through such other public medium as the Company may use at such time. 
  
 (d) Fundamental Change Repurchase Notice. In order to exercise its rights under Section 11.08 hereof,
a Holder must deliver to the Paying Agent: 
  
 (1) a written notice of repurchase (a “Fundamental Change Repurchase Notice”), substantially in the form of Exhibit D hereto, at any time from the opening of business on the date of the Fundamental Change Company
Notice until the close of business on Business Day prior to the Fundamental Change Repurchase Date stating: 
  
 (A) the certificate number (if such Security is held other than in global form) of the Security which the Holder will deliver to be
purchased; 
  
 (B) the portion of the Principal
Amount of the Security which the Holder will deliver to be purchased, which portion must be in a Principal Amount of $1,000 or integral multiples thereof; and 
  

(C) that such Security shall be purchased as of the Fundamental Change Repurchase Date pursuant to the terms and conditions specified
in the Securities and in this Indenture; and 
  
 (2) the Security (if such Security is held other than in global form) for cancellation prior to, on or after the Fundamental Change Repurchase Date (together with all necessary endorsements) at the offices of the Paying Agent, such delivery
being a condition to receipt by the Holder of the Fundamental Change Repurchase Price therefor; provided that such Fundamental Change Repurchase Price shall be so paid pursuant to this Section 11.08 only if the Security so delivered to the Paying
Agent shall conform in all respects to the description thereof in the related Fundamental Change Repurchase Notice. 
  
 The Company shall purchase from the Holder thereof, pursuant to this Section 11.08, a portion of a Security if the Principal Amount of such portion is
$1,000 or an integral multiple of $1,000 if so requested by the Holder. Provisions of this Indenture that apply to the repurchase of all of a Security also apply to the repurchase of such portion of such Security. 
  

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 Any repurchase by the Company contemplated pursuant to the provisions of this Section 11.08 shall be
consummated by the delivery to the Paying Agent of the consideration to be received by the Holder promptly following the later of the Fundamental Change Repurchase Date and the time of delivery of the Security. 
  
 Notwithstanding anything herein to the contrary, any Holder delivering to the
Paying Agent the Fundamental Change Repurchase Notice contemplated by this Section 11.08(d) shall have the right to withdraw such Fundamental Change Repurchase Notice at any time prior to the close of business on the Business Day prior to the
Fundamental Change Repurchase Date by delivery of a written notice of withdrawal to the Paying Agent in accordance with Section 11.09. 
  
 The Paying Agent shall promptly notify the Company of the receipt by it of any Fundamental Change Repurchase Notice or written notice of withdrawal
thereof. 
  
 (e) Payment of Fundamental Change
Repurchase Price. The Securities to be repurchased pursuant to this Section 11.08 shall be paid for in cash; provided that if a Fundamental Change occurs as a result of a Change of Control Event, the Securities to be repurchased may be paid for,
in whole or in part, at the election of the Company, in cash or Common Stock or any combination of cash and Common Stock, subject to the conditions set forth in clause (f) of this Section 11.08. 
  
 (f) Conditions for Election to Pay Fundamental Change
Repurchase Price in Common Stock. If the Company elects to pay all or any portion of the Fundamental Change Repurchase Price in Common Stock, the number of shares of Common Stock to be paid will equal the quotient obtained by dividing (i) the
portion of the Fundamental Change Repurchase Price to be paid in shares of Common Stock by (ii) 97% of the average Closing Price of the shares of Common Stock for the five Trading Day period ending on the second Business Day immediately preceding
the Fundamental Change Repurchase Date, appropriately adjusted to take into account the occurrence, during the period commencing on the first of the Trading Days during the five Trading Day period and ending on the Fundamental Change Repurchase
Date, of any event described in Section 13.06, subject to the next succeeding paragraph. The Company shall designate, in the Fundamental Change Company Notice delivered pursuant to clause (c) of Section 11.08, whether it will repurchase the
Securities for cash or shares of Common Stock, or, if a combination thereof, the percentages of the Fundamental Change Repurchase Price of Securities in respect of which it will pay in cash or shares of Common Stock; provided that the Company will
pay cash for fractional interests in shares of Common Stock. For purposes of determining the existence of potential fractional interests, all Securities subject to repurchase by the Company held by a Holder shall be considered together (no matter
how many separate certificates are to be presented). Each Holder whose Securities are repurchased pursuant to this Section 11.08 shall receive the same percentage of cash or shares of Common Stock in payment of the Fundamental Change Repurchase
Price for such Securities, except with regard to the payment of cash in lieu of fractional shares of Common Stock. The Company may not change its election with respect to the consideration (or components or percentages of components thereof) to be
paid once the Company has given its Fundamental Change Company Notice to 

  

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Holders except as set forth in the next succeeding paragraph in the event of a failure to satisfy, prior to the close of business on the Business Day prior
to the Fundamental Change Repurchase Date, any condition to the payment of the Fundamental Change Repurchase Price, in whole or in part, in shares of Common Stock. 
  
 The Company shall, at least three Business Days prior to delivering the Fundamental Change Company Notice, deliver an
Officers’ Certificate to the Trustee specifying: 
  
 (i) the manner of payment selected by the Company, 
  
 (ii) the information required by the Company Repurchase Notice pursuant to clause (c) of Section 11.08, 
  
 (iii) if the Company elects to pay the Fundamental Change Repurchase Price, or a specified percentage thereof, in shares of Common Stock,
that the conditions to such manner of payment set forth in this clause (f) have been or will be complied with, and 
  
 (iv) whether the Company desires the Trustee to give the Fundamental Change Company Notice required by clause (c) of Section 11.08.

  
 The Company’s right to exercise its election to
repurchase Securities through the issuance of shares of Common Stock shall be conditioned upon: 
  
 (i) the Company’s giving a timely Fundamental Change Company Notice containing an election to purchase all or a specified percentage
of the Securities with shares of Common Stock as provided herein; 
  
 (ii) the registration of such shares of Common Stock under the Securities Act and, if required, the Exchange Act; 
  
 (iii) the listing of such shares of Common Stock on a United States national securities exchange or the quotation of such shares of Common
Stock in an inter-dealer quotation system of any registered United States national securities association, in each case, if the Common Stock is then listed on a national securities exchange or quoted in an inter-dealer quotation system; 

 
 (iv) any necessary qualification or registration of such
shares of Common Stock under applicable state securities laws or the availability of an exemption from such qualification and registration; and 
  
 (v) the receipt by the Trustee of an (A) Officers’ Certificate stating that the terms of the issuance of the shares of Common Stock
are in conformity with this Indenture, (B) an Opinion of Counsel to the effect that the shares of Common Stock to be issued by the Company in payment of the 

  

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Fundamental Change Repurchase Price in respect of the Securities have been duly authorized and, when issued and delivered pursuant to the terms of this
Indenture in payment of the Fundamental Change Repurchase Price in respect of the Securities, will be validly issued, fully paid and non-assessable and (c) an Officer’s Certificate, stating that the conditions to the issuance of the shares of
Common Stock have been satisfied. 
  
 Such Officers’
Certificate shall also set forth the number of shares of Common Stock to be issued for each $1,000 principal amount of Securities upon their Stated Maturity and the Closing Price of a share of Common Stock on each Trading Day during the period
commencing on the fifth Trading Day immediately preceding but ending on the third Business Day prior to the applicable Fundamental Change Repurchase Date. If the foregoing conditions are not satisfied prior to the close of business on the Business
Day immediately preceding the Fundamental Change Repurchase Date and the Company has elected to repurchase the Securities through the issuance of shares of Common Stock, the Company shall pay the entire Fundamental Change Repurchase Price of the
Securities in cash. 
  
 Promptly after determination of the actual
number of shares of Common Stock to be issued upon repurchase of Securities, the Company shall be required to disseminate a press release through Dow Jones & Company, Inc. or Bloomberg Business News containing this information or publish the
information on the Company’s web site or through such other public medium as the Company may use at that time. 
  
 All shares of Common Stock delivered upon repurchase of the Securities shall be duly authorized, validly issued, fully paid and nonassessable. 

 
 If a Holder of a repurchased Security is paid in shares of Common Stock,
the Company shall pay any documentary, stamp or similar issue or transfer tax due on such issue of Common Stock. However, the Holder shall pay any such tax which is due because the Holder requests the Common Stock to be issued in a name other than
the Holder’s name. The Trustee (or other paying agent appointed by the Company) may refuse to deliver the certificates representing the shares of Common Stock being issued in a name other than the Holder’s name until the Trustee (or other
paying agent appointed by the Company) receives a sum sufficient to pay any tax which will be due because the shares of Common Stock are to be issued in a name other than the Holder’s name. Nothing herein shall preclude any income tax
withholding required by law or regulations. 
  
 (g) Procedure Upon Repurchase. The Company shall deposit cash or Common Stock, if permitted hereunder, at the time and in the manner as provided in Section 11.10, sufficient to pay the aggregate Fundamental Change Repurchase Price of
all Securities to be purchased pursuant to this Section 11.08. 
  
 Section 11.09. Effect of Fundamental Change Repurchase Notice. Upon receipt by the Paying Agent of the Fundamental Change Repurchase Notice specified in clause (d) of Section 11.08, the Holder of the Security in respect of which such
Fundamental Change Repurchase 

  

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Notice was given shall (unless such Fundamental Change Repurchase Notice is withdrawn as specified in the following two paragraphs) thereafter be entitled to
receive solely the Fundamental Change Repurchase Price with respect to such Security. Such Fundamental Change Repurchase Price shall be paid to such Holder, subject to receipt of funds by the Paying Agent, promptly following the later of (x) the
Fundamental Change Repurchase Date with respect to such Security (provided the conditions in clause (d) of Section 11.08, have been satisfied) and (y) the time of delivery of such Security to the Paying Agent by the Holder thereof in the manner
required by clause (d) of Section 11.08. Securities in respect of which a Fundamental Change Repurchase Notice has been given by the Holder thereof may not be converted pursuant to Article 13 on or after the date of the delivery of such Fundamental
Change Repurchase Notice unless such Fundamental Change Repurchase Notice has first been validly withdrawn as specified in the following two paragraphs. 
  
 A Fundamental Change Repurchase Notice may be withdrawn only by means of a written notice of withdrawal delivered to the office of the Paying Agent in
accordance with the procedures set forth in the Fundamental Change Company Notice at any time prior to the close of business on the Business Day prior to the Fundamental Change Repurchase Date specifying: 
  
 (i) the Principal Amount of the Security with respect to
which such notice of withdrawal is being submitted; and 
  
 (ii) the certificate number (if such Security is held in other than global form) of the Security in respect of which such notice of withdrawal is being submitted; and 
  
 (iii) the Principal Amount, if any, of such Security which
remains subject to the original Fundamental Change Repurchase Notice and which has been or will be delivered for purchase or repurchase by the Company. 
  
 There shall be no repurchase of any Securities pursuant to Section 11.08 if there has occurred (prior to, on or after, as the case may be, the giving, by
the Holders of such Securities, of the required Fundamental Change Repurchase Notice) and is continuing an Event of Default (other than a default in the payment of the Fundamental Change Repurchase Price with respect to such Securities). The Paying
Agent will promptly return to the respective Holders thereof any Securities (x) with respect to which a Fundamental Change Repurchase Notice has been withdrawn in compliance with this Indenture, or (y) held by it during the continuance of an Event
of Default (other than a default in the payment of the Fundamental Change Repurchase Price with respect to such Securities) in which case, upon such return, the Fundamental Change Repurchase Notice with respect thereto shall be deemed to have been
withdrawn. 
  
 Section 11.10. Deposit of Fundamental Change
Repurchase Price. Prior to 10:00 a.m. (local time in The City of New York) on the Business Day preceding the Fundamental Change Repurchase Date, the Company shall deposit with the Trustee or with the Paying Agent (or, if the Company or a
Subsidiary or an Affiliate of either of them is acting as the Paying Agent, shall segregate and hold in trust as provided herein) an amount of money (in immediately available 

  

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funds if deposited on such Business Day) or Common Stock, if permitted hereunder, sufficient to pay the Fundamental Change Repurchase Price of all the
Securities or portions thereof which are to be repurchased as of the Fundamental Change Repurchase Date. The Company shall promptly notify the Trustee in writing of the amount of any deposits of cash or Common Stock made pursuant to Section 11.10.

  
 Section 11.11. Securities Repurchased in Whole or in
Part. Any Security which is to be repurchased, whether in whole or in part, shall be surrendered at the office of the Paying Agent (with, if the Company or the Trustee so requires, due endorsement by, or a written instrument of transfer in form
satisfactory to the Company and the Trustee duly executed by, the Holder thereof or such Holder’s attorney duly authorized in writing) and the Company shall execute and the Trustee shall authenticate and deliver to the Holder of such Security,
without service charge, a new Security or Securities, of any authorized denomination as requested by such Holder in aggregate Principal Amount equal to, and in exchange for, the portion of the Principal Amount of the Security so surrendered which is
not repurchased. 
  
 Section 11.12. Covenant to Comply With
Securities Laws Upon Repurchase of Securities. In connection with any offer to repurchase Securities under Section 11.08 (provided that such offer or repurchase constitutes an “issuer tender offer” for purposes of Rule 13e-4 (which
term, as used herein, includes any successor provision thereto) under the Exchange Act at the time of such offer or repurchase), the Company shall (i) comply with Rule 13e-4 and Rule 14e-1 under the Exchange Act, (ii) file the related Schedule TO
(or any successor schedule, form or report) under the Exchange Act, and (iii) otherwise comply with all Federal and state securities laws so as to permit the rights and obligations under Section 11.08 to be exercised in the time and in the manner
specified in Section 11.08, as applicable. 
  
 Section 11.13.
Repayment to the Company. The Trustee and the Paying Agent shall return to the Company any cash that remains unclaimed, together with interest or dividends, if any, thereon, held by them for the payment of the Fundamental Change Repurchase
Price; provided that to the extent that the aggregate amount of cash or Common Stock deposited by the Company pursuant to Section 11.10 exceeds the aggregate Fundamental Change Repurchase Price of the Securities or portions thereof which the
Company is obligated to repurchase as of the Fundamental Change Repurchase Date, then as soon as practicable following the Fundamental Change Repurchase Date, the Trustee or the Paying Agent, as the case may be, shall return any such excess to the
Company. 
  
 ARTICLE 12 
 Interest Payments on the Securities 
  
 Section 12.01. Interest Rate. (a) Interest on the Securities shall accrue at a rate of 31⁄2% per annum and shall be payable semi-annually in
arrears on each Interest Payment Date to Holders of record on the Record Date immediately preceding such Interest Payment Date. Interest will be computed on the basis of a 360-day year comprised of twelve 30-day months. Interest on the Securities
shall accrue from the most recent date to which interest has been paid, 

  

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or if no interest has been paid, from May 10, 2004, until the Principal Amount is paid or duly made available for payment. 
  
 (b) Interest on any Security that is payable, and is
punctually paid or duly provided for, on any Interest Payment Date shall be paid to the Person in whose name that Security is registered at the close of business on the Record Date for such interest at the office or agency of the Company maintained
for such purpose. Each installment of interest on any Security shall be made by check mailed to the address of the Holder specified in the register of Securities; provided, however, that, with respect to any Holder of Securities with an aggregate
principal amount in excess of $2,000,000, at the request of such Holder in writing to the Company, interest on such Holder’s Securities shall be paid by wire transfer in immediately available funds in accordance with the written wire transfer
instruction supplied by such Holder from time to time to the Trustee and Paying Agent (if different from the Trustee) at least ten days prior to the applicable Interest Payment Date. In the case of a permanent Global Security, interest payable on
any Interest Payment Date will be paid to the Depositary, with respect to that portion of such permanent Global Security held for its account by Cede & Co. for the purpose of permitting such party to credit the interest received by it in respect
of such permanent Global Security to the accounts of the beneficial owners thereof. 
  
 ARTICLE 13 
 Conversion 
  
 Section 13.01. Conversion Privilege. (a) Subject to the further provisions of this Article 13, a Holder of a Security
may convert the Principal Amount of such Security (or a portion thereof equal to $1,000 or any integral multiple of $1,000 in excess thereof) into Common Stock at any time prior to the close of business on the Business Day prior to the Stated
Maturity. 
  
 (b) Conversion Period.
Notwithstanding the foregoing, if such Security is submitted or presented for repurchase pursuant to Article 11, such conversion right shall terminate at the close of business on the Business Day prior to the Fundamental Change Repurchase Date for
such Security or such earlier date as the Holder presents such Security for repurchase (unless the Company shall default when due, in which case the conversion right shall terminate at the close of business on the date such default is cured and such
Security is repurchased). 
  
 (c) Conversion
Rate; Conversion Price. The conversion rate per Security (the “Conversion Rate”) shall be that set forth in paragraph 5 in the Securities, subject to adjustment as herein set forth. The initial Conversion Rate is 150.5571 shares
of Common Stock per $1,000 principal amount of Securities. The “Conversion Price” at any particular time is determined by dividing $1,000 by the then-applicable Conversion Rate. 
  
 (d) Securities Converted in Whole or in Part.
Provisions of this Indenture that apply to conversion of all of a Security also apply to conversion of a portion of a Security. 
  

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 (e) Rights of Holders. A Holder of Securities is not entitled to any rights of a
holder of Common Stock until such Holder has converted its Securities to Common Stock, and only to the extent such Securities are deemed to have been converted into Common Stock pursuant to this Article 13. 
  
 Section 13.02. Conversion Procedure. 
  
 (a) To convert a Security, a Holder must (i) complete and
manually sign the conversion notice on the back of the Security or facsimile of the conversion notice and deliver such notice to a Conversion Agent, (ii) surrender the Security to a Conversion Agent, (iii) furnish appropriate endorsements and
transfer documents if required by a Registrar or a Conversion Agent and (iv) pay any transfer or similar tax, if required. Such notice is hereinafter referred to as a “Notice of Conversion.” A Security shall be deemed to have been
converted as of the close of business on the date (the “Conversion Date”) on which the Holder has complied with the immediately preceding sentence of this clause (a) of Section 13.02. Anything herein to the contrary notwithstanding,
in the case of Global Securities, a Notice of Conversion shall be delivered and such Securities shall be surrendered for conversion in accordance with the rules and procedures of DTC as in effect from time to time. 
  
 (b) The Company will, as soon as practicable after the
Conversion Date, issue, or cause to be issued, and deliver to the Conversion Agent or to such Holder, or such Holder’s nominee or nominees, certificates for the number of full shares of Common Stock, if any, to which such Holder shall be
entitled. The Person or Persons entitled to receive such Common Stock upon such conversion shall be treated for all purposes as the record holder or holders of such Common Stock, as of the close of business on the applicable Conversion Date;
provided, however, that no surrender of a Security on any date when the stock transfer books of the Company shall be closed shall be effective to constitute the Person or Persons entitled to receive the shares of Common Stock upon such conversion as
the record holder or holders of such shares of Common Stock on such date, but such surrender shall be effective to constitute the Person or Persons entitled to receive such shares of Common Stock as the record holder or holders thereof for all
purposes at the close of business on the next succeeding day on which such stock transfer books are open; provided further that such conversion shall be at the Conversion Rate in effect on the Conversion Date as if the stock transfer books of the
Company had not been closed. Upon conversion of a Security, such Person shall no longer be a Holder of such Security. Except as otherwise provided in Section 13.06, no payment or adjustment will be made for dividends or distributions on shares of
Common Stock issued upon conversion of a Security. 
  
 All
Securities or portions thereof surrendered for conversion during the period from the close of business on the Record Date for any Interest Payment Date to the close of business on the Business Day next preceding the following Interest Payment Date
shall (unless such Securities or portion thereof being converted shall have been called for redemption on a Redemption Date which occurs during the period from the close of business on such Record Date to the close of business on the Business Day
next preceding the following Interest Payment 

  

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Date) be accompanied by payment, in funds acceptable to the Company, of an amount equal to the interest otherwise payable on such Interest Payment Date on
the Principal Amount being converted; provided, however, that no such payment need be made if there shall exist at the time of conversion a default in the payment of interest on the Securities. 
  
 (c) If a Holder converts more than one Security at the same
time, the number of shares of Common Stock issuable upon the conversion shall be based on the aggregate Principal Amount of Securities converted. 
  
 (d) Upon surrender of a Security that is converted in part, the Company shall execute, and the Trustee shall authenticate and deliver to
the Holder, a new Security equal in principal amount to the unconverted portion of the Security surrendered. 
  
 (e) If the last day on which Security may be converted is not a Business Day in a place where a Conversion Agent is located, the
Securities may be surrendered to that Conversion Agent on the next succeeding Business Day. 
  
 (f) Holders that have already delivered a Fundamental Change Repurchase Notice with respect to a Security may not surrender such Security
for conversion until the Fundamental Change Repurchase Notice has been withdrawn in accordance with the procedures set forth in Section 11.09. 
  
 Section 13.03. Fractional Shares. The Company will not issue fractional shares of Common Stock upon conversion of Securities. In lieu thereof, the
Company will pay an amount in cash for the current market value of the fractional shares. The current market value of a fractional share shall be determined, (calculated to the nearest 1/1000th of a share) by multiplying the Closing Price of the
Common Stock on the Trading Day immediately prior to the Conversion Date by such fractional share and rounding the product to the nearest whole cent. 
  
 Section 13.04. Taxes on Conversion. If a Holder converts a Security, the Company shall pay any documentary, stamp or similar issue or transfer tax
due on the issuance of shares of Common Stock upon such conversion. However, the Holder shall pay any such tax which is due because the Holder requests the shares to be issued in a name other than the Holder’s name. The Conversion Agent may
refuse to deliver the certificate representing the Common Stock being issued in a name other than the Holder’s name until the Conversion Agent receives a sum sufficient to pay any tax which will be due because the shares are to be issued in a
name other than the Holder’s name. Nothing herein shall preclude any tax withholding required by law or regulation. 
  
 Section 13.05. Company to Provide Stock. 
  
 (a) The Company shall, prior to issuance of any Securities hereunder, and from time to time as may be necessary, reserve, out of its
authorized but unissued Common Stock, a sufficient number of shares of Common Stock to permit the conversion of all 

  

 59 

 
outstanding Securities into shares of Common Stock (including after taking into account any adjustments to the Conversion Rate pursuant to Section 13.06).

  
 (b) All shares of Common Stock delivered upon
conversion of the Securities shall be newly issued shares, shall be duly authorized, validly issued, fully paid and nonassessable and shall be free from preemptive rights and free of any lien or adverse claim. 
  
 (c) The Company will endeavor promptly to comply with all
federal and state securities laws regulating the offer and delivery of shares of Common Stock upon conversion of Securities, if any, and will list or cause to have quoted such shares of Common Stock on each national securities exchange or on the New
York Stock Exchange, the Nasdaq National Market or other over-the-counter market or such other market on which the Common Stock is then listed or quoted; provided, however, that if rules of such automated quotation system or exchange permit the
Company to defer the listing of such Common Stock until the first conversion of the Securities into Common Stock in accordance with the provisions of this Indenture, the Company covenants to list such Common Stock issuable upon conversion of the
Securities in accordance with the requirements of such automated quotation system or exchange at such time. Any Common Stock issued upon conversion of a Security hereunder which at the time of conversion was a Transfer Restricted Security will
remain a Transfer Restricted Security. 
  
 Section 13.06.
Adjustment of Conversion Rate. The Conversion Rate shall be adjusted from time to time by the Company as follows: 
  
 (a) In case the Company shall (i) pay a dividend on its Common Stock in shares of Common Stock, (ii) make a distribution on its Common
Stock in shares of Common Stock, (iii) subdivide its outstanding Common Stock into a greater number of shares, or (iv) combine its outstanding Common Stock into a smaller number of shares, the Conversion Rate in effect immediately prior thereto
shall be adjusted so that the Holder of any Security thereafter surrendered for conversion shall be entitled to receive that number of shares of Common Stock which it would have owned had such Security been converted immediately prior to the
happening of such event. An adjustment made pursuant to this subsection (a) shall become effective immediately after the record date in the case of a dividend or distribution and shall become effective immediately after the effective date in the
case of subdivision or combination. 
  
 (b) In
case the Company shall issue rights or warrants (other than pursuant to a stockholder rights plan) to all or substantially all holders of its Common Stock entitling them (for a period commencing no earlier than the record date described below and
expiring not more than 60 days after such record date) to subscribe for or purchase shares of Common Stock (or securities convertible into Common Stock) at a price per share (or having a conversion price per share) less than the Closing Price per
share of Common Stock on the Business Day immediately prior to the date of announcement of such issuance, the Conversion Rate in effect shall be adjusted so that the same shall equal the rate determined by multiplying the Conversion Rate in effect
immediately prior to such announcement by a fraction of which the numerator shall be the number of shares of Common Stock outstanding at the close of business on the date of announcement plus the number of additional shares of Common Stock offered
(or 

  

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into which the convertible securities so offered are convertible), and the denominator of which shall be the number of shares of Common Stock outstanding at
the close of business on the date of announcement plus the number of shares which the aggregate offering price of the total number of shares of Common Stock so offered (or the aggregate conversion price of the convertible securities so offered,
which shall be determined by multiplying the number of shares of Common Stock issuable upon conversion of such convertible securities by the conversion price per share of Common Stock pursuant to the terms of such convertible securities) would
purchase at the Current Market Price per share of Common Stock on the Business Day immediately preceding the date of announcement of such issuance. Such adjustment shall be made successively whenever any such rights or warrants are issued, and shall
become effective on the day following the date of announcement of such issuance. If at the end of the period during which such rights or warrants are exercisable not all rights or warrants shall have been exercised, the adjusted Conversion Rate
shall be immediately readjusted to what it would have been based upon the number of additional shares of Common Stock actually issued (or the number of shares of Common Stock issuable upon conversion of convertible securities actually issued).

  
 (c) In case the Company shall distribute to
all or substantially all holders of its Common Stock any shares of capital stock of the Company (other than Common Stock), evidences of indebtedness or other non-cash assets (including securities of any person other than the Company but excluding
(1) dividends or distributions paid exclusively in cash or (2) dividends or distributions referred to in subsection (a) of this Section 13.06), or shall distribute to all or substantially all holders of its Common Stock rights or warrants to
subscribe for or purchase any of its securities (excluding those rights and warrants referred to in subsection (b) of this Section 13.06 and also excluding the distribution of rights to all holders of Common Stock pursuant to a Rights Plan (as
defined below) or the detachment of such rights to the extent set forth in the second following paragraph), then in each such case the Conversion Rate shall be adjusted so that the same shall equal the rate determined by multiplying the current
Conversion Rate by a fraction of which the numerator shall be the Current Market Price per share of the Common Stock on the record date mentioned below and the denominator shall be the Current Market Price per share of the Common Stock on such
record date less the fair market value on such record date (as determined by the Board of Directors, whose determination shall be conclusive evidence of such fair market value and which shall be evidenced by an Officers’ Certificate delivered
to the Trustee) of the portion of the capital stock, evidences of indebtedness or other non-cash assets so distributed or of such rights or warrants applicable to one share of Common Stock (determined on the basis of the number of shares of Common
Stock outstanding on the record date). Such adjustment shall be made successively whenever any such distribution is made and shall become effective immediately after the record date for the determination of shareholders entitled to receive such
distribution. 
  
 In the event the then fair market value (as so
determined) of the portion of the Capital Stock, evidences of indebtedness or other non-cash assets so distributed or of such rights or warrants applicable to one share of Common Stock is equal to or greater than the Current Market Price per share
of the Common Stock on such record date, in lieu of the foregoing adjustment, 

  

 61 

 
adequate provision shall be made so that each Holder of a Security shall have the right to receive upon conversion the amount of Capital Stock, evidences of
indebtedness or other non-cash assets so distributed or of such rights or warrants such Holder would have received had such Holder converted each Security on such record date. In the event that such dividend or distribution is not so paid or made,
the Conversion Rate shall again be adjusted to be the Conversion Rate which would then be in effect if such dividend or distribution had not been declared. If the Board of Directors determines the fair market value of any distribution for purposes
of this Section 13.06 by reference to the actual or when issued trading market for any securities, it must in doing so consider the prices in such market over the same period used in computing the Current Market Price of the Common Stock.

  
 In the event that the Company has in effect a preferred shares
rights plan (“Rights Plan”), upon conversion of the Securities into Common Stock, to the extent that the Rights Plan is still in effect upon such conversion, the Holders of Securities will receive, in addition to the Common Stock,
the rights described therein (whether or not the rights have separated from the Common Stock at the time of conversion), subject to the limitations set forth in the Rights Plan. If the Rights Plan provides that upon separation of rights under such
plan from the Company’s Common Stock that the Holders would not be entitled to receive any such rights in respect of the Common Stock issuable upon conversion of the Securities, the Conversion Rate will be adjusted as provided in this Section
13.06(c) (with such separation deemed to be the distribution of such rights), subject to readjustment in the event of the expiration, termination or redemption of the rights. Any distribution of rights or warrants pursuant to a Rights Plan that
would allow a Holder to receive upon conversion, in addition to the Common Stock, the rights described therein (whether or not the rights have separated from the Common Stock at the time of conversion), shall not constitute a distribution of rights
or warrants pursuant to this Article 13. 
  
 Rights or warrants
distributed by the Company to all holders of Common Stock entitling the holders thereof to subscribe for or purchase shares of the Company’s Capital Stock (either initially or under certain circumstances), which rights or warrants, until the
occurrence of a specified event or events (“Trigger Event”): (i) are deemed to be transferred with such shares of Common Stock; (ii) are not exercisable; and (iii) are also issued in respect of future issuances of Common Stock,
shall be deemed not to have been distributed for purposes of this Section 13.06 (and no adjustment to the Conversion Rate under this Section 13.06 will be required) until the occurrence of the earliest Trigger Event, whereupon such rights and
warrants shall be deemed to have been distributed and an appropriate adjustment (if any is required) to the Conversion Rate shall be made under this clause (c) of Section 13.06. If any such right or warrant, including any such existing rights or
warrants distributed prior to the date of this Indenture, are subject to events, upon the occurrence of which such rights or warrants become exercisable to purchase different securities, evidences of indebtedness or other assets, then the date of
the occurrence of any and each such event shall be deemed to be the date of distribution and record date with respect to new rights or warrants with such rights (and a termination or expiration of the existing rights or warrants without exercise by
any of the holders thereof). In addition, in the event of any distribution (or deemed distribution) of rights or warrants, or any Trigger Event or other event (of the type described in the preceding sentence) with respect 

  

 62 

 
thereto that was counted for purposes of calculating a distribution amount for which an adjustment to the Conversion Rate under this Section 13.06 was made,
(1) in the case of any such rights or warrants which shall all have been redeemed or repurchased without exercise by any holders thereof, the Conversion Rate shall be readjusted upon such final redemption or repurchase to give effect to such
distribution or Trigger Event, as the case may be, as though it were a cash distribution, equal to the per share redemption or repurchase price received by a holder or holders of Common Stock with respect to such rights or warrants (assuming such
holder had retained such rights or warrants), made to all holders of Common Stock as of the date of such redemption or repurchase, and (2) in the case of such rights or warrants which shall have expired or been terminated without exercise by any
holders thereof, the Conversion Rate shall be readjusted as if such rights and warrants had not been issued. 
  
 (d) In case the Company shall, by dividend or otherwise, at any time distribute (a “Triggering Distribution”) to all or
substantially all holders of its Common Stock cash, the Conversion Rate shall be increased so that the same shall equal the rate determined by multiplying such Conversion Rate in effect on the Business Day immediately prior to the record date (the
“Determination Date”) for such Triggering Distribution is declared by the Company by a fraction of which the numerator shall be the Current Market Price per share of the Common Stock on the Determination Date, and the denominator
shall be the Current Market Price per share of the Common Stock on the Determination Date less the aggregate amount of cash so distributed applicable to one share of Common Stock (determined on the basis of the number of shares of Common Stock
outstanding on the date such distribution is made), such increase to become effective immediately prior to the opening of business on the day following the date on which the Triggering Distribution is paid. It is expressly understood that a stock
buyback, repurchase or similar transaction or program shall in no event be considered a Triggering Distribution for purposes of this clause (d) or (e) of Section 13.06. 
  
 (e) In case the Company or any of its Subsidiaries shall purchase any shares of the Company’s Common
Stock by means of a tender offer, then, effective immediately prior to the opening of business on the day after the last date (the “Expiration Date”) tenders could have been made pursuant to such tender offer (as it may be amended)
(the last time at which such tenders could have been made on the Expiration Date is hereinafter sometimes called the “Expiration Time”), the Conversion Rate shall be increased so that the same shall equal the rate determined by
multiplying the Conversion Rate in effect immediately prior to the close of business on the Expiration Date by a fraction of which the numerator shall be the sum of (x) the aggregate consideration (determined as set forth below) payable to
stockholders of the Company based on the acceptance (up to any maximum specified in the terms of the tender offer) of all shares validly tendered and not withdrawn as of the Expiration Time (the shares deemed so accepted, up to any such maximum,
being referred to as the “Purchased Shares”) and (y) the product of the number of shares of Common Stock outstanding (less any Purchased Shares and excluding any shares held in the treasury of the Company) immediately prior to the
Expiration Time and the Current Market Price per share of Common Stock (as determined in accordance with clause (f) of Section 13.06), and the denominator shall be the product of the number of shares of Common Stock outstanding (including Purchased
Shares but excluding any shares held 

  

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in the treasury of the Company) immediately prior to the Expiration Time multiplied by the Current Market Price per share of the Common Stock (as determined
in accordance with clause (f) of Section 13.06). For purposes of this clause (e) of Section 13.06, the aggregate consideration in any such tender offer shall equal the sum of the aggregate amount of cash consideration and the aggregate fair market
value (as determined by the Board of Directors, whose determination shall be conclusive evidence thereof and which shall be evidenced by an Officers’ Certificate delivered to the Trustee) of any other consideration payable in such tender offer.
In the event that the Company is obligated to purchase shares pursuant to any such tender offer, but the Company is permanently prevented by applicable law from effecting any or all such purchases or any or all such purchases are rescinded, the
Conversion Rate shall again be adjusted to be the Conversion Rate which would have been in effect based upon the number of shares actually purchased. If the application of this clause (e) of Section 13.06 to any tender offer would result in a
decrease in the Conversion Rate, no adjustment shall be made for such tender offer under this Section 13.06(e). For purposes of this clause (e) of Section 13.06, the term “tender offer” shall mean and include both tender offers and
exchange offers, all references to “purchases” of shares in tender offers (and all similar references) shall mean and include both the purchase of shares in tender offers and the acquisition of shares pursuant to exchange offers, and all
references to “tendered shares” (and all similar references) shall mean and include shares tendered in both tender offers and exchange offers. 
  
 (f) For the purpose of any computation under clauses (b), (c) and (d) of Section 13.06, the current market price (the “Current
Market Price”) per share of Common Stock on any date shall be deemed to be the average of the daily Closing Prices for the ten consecutive Trading Days commencing 11 Trading Days before the record date with respect to distributions,
issuances or other events requiring such computation under Section 13.06. For purposes of any computation under subsection (e) of this Section 13.06, the Current Market Price per share of Common Stock shall be deemed to be the average of the daily
Closing Prices for the ten consecutive Trading Days commencing on the Trading Day next succeeding the Expiration Date. 
  
 (g) In any case in which this Section 13.06 shall require that an adjustment be made following a record date, an announcement date or a
Determination Date or Expiration Date, as the case may be, established for purposes of this Section 13.06, the Company may elect to defer (but only until five Business Days following the filing by the Company with the Trustee of the certificate
described in Section 13.09) issuing to the Holder of any Security converted after such record date or announcement date or Determination Date or Expiration Date the shares of Common Stock and other capital stock of the Company issuable upon such
conversion over and above the shares of Common Stock and other capital stock of the Company issuable upon such conversion only on the basis of the Conversion Rate prior to adjustment; and, in lieu of the shares the issuance of which is so deferred,
the Company shall issue or cause its transfer agents to issue due bills or other appropriate evidence prepared by the Company of the right to receive such shares. If any distribution in respect of which an adjustment to the Conversion Rate is
required to be made as of the record date or announcement date or Determination Date or Expiration Date therefor is not thereafter made or paid by the Company 

  

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for any reason, the Conversion Rate shall be readjusted to the Conversion Rate which would then be in effect if such record date had not been fixed or such
announcement date or effective date or Determination Date or Expiration Date had not occurred. 
  
 Section 13.07. No Adjustment. (a) No adjustment need be made for issuances of Common Stock pursuant to a Company plan for reinvestment of dividends or interest or for a change in the par value or a change to no
par value of the Common Stock. 
  
 (b) To the
extent that the Securities become convertible into the right to receive cash, no adjustment need be made thereafter as to the cash. Interest will not accrue on the cash due. 
  
 (c) No adjustment in the Conversion Rate shall be made pursuant to this Section 13.06 if the Holders may
participate in the transaction that would otherwise give rise to an adjustment pursuant to Section 13.06. 
  
 (d) Other than as described above in Section 13.06, no adjustment to the Conversion Rate shall be required for any issuance of Common
Stock or convertible or exchangeable securities or rights to purchase Common Stock or convertible or exchangeable securities. 
  
 (e) No adjustment in the Conversion Rate shall be made pursuant to Section 13.06 unless the adjustment would require a change of at least
1% of the Conversion Rate in effect immediately prior to the event otherwise giving rise to such adjustment; provided, however, that any such events for which adjustments are not made pursuant to this sentence shall be carried forward and such
adjustment shall be made at such time as the aggregate amount of all such adjustments heretofore not made would require an adjustment equal to or in excess of 1% of the Conversion Rate in effect immediately prior to the first of such events.

  
 Section 13.08. Adjustment for Tax Purposes. The Company
shall be entitled to make such increases in the Conversion Rate, in addition to those required by Section 13.06, as it in its discretion shall determine to be advisable in order that any stock dividends, subdivisions of shares, distributions of
rights to purchase stock or securities or distributions of securities convertible into or exchangeable for stock hereafter made by the Company to its stockholders shall not be taxable. 
  
 Section 13.09. Notice of Conversion Rate Adjustment. Whenever the Conversion Rate is adjusted, the Company shall
promptly mail to Securityholders a notice of the adjustment and file with the Trustee an Officers’ Certificate briefly stating the facts requiring the adjustment and the manner of computing it. Unless and until the Trustee shall receive an
Officers’ Certificate setting forth an adjustment of the Conversion Rate, the Trustee may assume without inquiry that the Conversion Rate has not been adjusted and that the last Conversion Rate of which it has knowledge remains in effect.

  

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 Section 13.10. Notice of Certain Transactions. In the event that: 
  
 (a) the Company takes any action which would require an
adjustment in the Conversion Rate; 
  
 (b) the
Company consolidates or merges with, or transfers all or substantially all of its property and assets to, another corporation and shareholders of the Company must approve the transaction; or 
  
 (c) there is a dissolution or liquidation of the Company,

  
 the Company shall mail to Holders and file with the Trustee a notice stating
the proposed record or effective date, as the case may be. The Company shall mail the notice at least ten days before such date. Failure to mail such notice or any defect therein shall not affect the validity of any transaction referred to in clause
(a), (b) or (c) of this Section 13.10. 
  
 Section 13.11.
Effect of Reclassification, Consolidation, Merger or Sale on Conversion Privilege. If any of the following shall occur, namely: (a) any reclassification or change of shares of Common Stock issuable upon conversion of the Securities (other
than a change in par value, or from par value to no par value, or from no par value to par value, or as a result of a subdivision or combination, or any other change for which an adjustment is provided in Section 13.06); (b) any consolidation or
merger or combination to which the Company is a party other than a merger in which the Company is the continuing corporation and which does not result in any reclassification of, or change (other than in par value, or from par value to no par value,
or from no par value to par value, or as a result of a subdivision or combination) in, outstanding shares of Common Stock; or (c) any sale or conveyance as an entirety or substantially as an entirety of the property and assets of the Company,
directly or indirectly, to any Person, then the Company, or such successor, purchasing or transferee corporation, as the case may be, shall, as a condition precedent to such reclassification, change, combination, consolidation, merger, sale or
conveyance, execute and deliver to the Trustee a supplemental indenture providing that the Holder of each Security then outstanding shall have the right to convert such Security into the kind and amount of shares of stock and other securities and
property (including cash) receivable upon such reclassification, change, combination, consolidation, merger, sale or conveyance by a holder of the number of shares of Common Stock deliverable upon conversion of such Security immediately prior to
such reclassification, change, combination, consolidation, merger, sale or conveyance. Such supplemental indenture shall provide for adjustments of the Conversion Rate which shall be as nearly equivalent as may be practicable to the adjustments of
the Conversion Rate provided for in this Article 13. If, in the case of any such consolidation, merger, combination, sale or conveyance, the stock or other securities and property (including cash) receivable thereupon by a holder of Common Stock
include shares of stock or other securities and property of a person other than the successor, purchasing or transferee corporation, as the case may be, in such consolidation, merger, combination, sale or conveyance, then such supplemental indenture
shall also be executed by such other person and shall contain such additional provisions to protect the interests of the Holders of the Securities as the Board of Directors shall reasonably consider necessary by reason of the foregoing. The
provisions of this 

  

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Section 13.11 shall similarly apply to successive reclassifications, changes, combinations, consolidations, mergers, sales or conveyances. 
  
 In the event the Company shall execute a supplemental indenture pursuant to
this Section 13.11, the Company shall promptly file with the Trustee (x) an Officers’ Certificate briefly stating the reasons therefor, the kind or amount of shares of stock or other securities or property (including cash) receivable by Holders
of the Securities upon the conversion of their Securities after any such reclassification, change, combination, consolidation, merger, sale or conveyance, any adjustment to be made with respect thereto and that all conditions precedent have been
complied with and (y) an Opinion of Counsel that all conditions precedent have been complied with, and shall promptly mail notice thereof to all Holders. 
  
 Section 13.12. Trustee’s Disclaimer. The Trustee shall have no duty to determine when an adjustment under this Article 13 should be made, how
it should be made or what such adjustment should be, but may accept as conclusive evidence of that fact or the correctness of any such adjustment, and shall be protected in relying upon, an Officers’ Certificate including the Officers’
Certificate with respect thereto which the Company is obligated to file with the Trustee pursuant to Section 13.09. The Trustee makes no representation as to the validity or value of any securities or assets issued upon conversion of Securities and
the Trustee shall not be responsible for the Company’s failure to comply with any provisions of this Article 13. 
  
 The Trustee shall not be under any responsibility to determine the correctness of any provisions contained in any supplemental indenture executed pursuant
to Section 13.11, but may accept as conclusive evidence of the correctness thereof, and shall be fully protected in relying upon, the Officers’ Certificate with respect thereto which the Company is obligated to file with the Trustee pursuant to
Section 13.11. 
  
 Section 13.13. Voluntary Increase. The
Company from time to time may increase the Conversion Rate by any amount for any period of time if the period is at least 20 days and if the increase is irrevocable during the period if the Board of Directors determines that such increase would be
in the best interest of the Company or the Board of Directors deems it advisable to avoid or diminish income tax to holders of shares of our Common Stock in connection with any stock or rights dividend or distribution or similar event, and the
Company provides 15 days prior notice of any increase in the Conversion Rate. 
  
 Section 13.14. Company Determination Final. Any determination that the Company or the Board of Directors must make pursuant to this Article 13 shall be conclusive if made in good faith and in accordance with
the provisions of this Article 13, absent manifest error, and set forth in a resolution of the Board of Directors. 
  

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 ARTICLE 14 
 Collateral Security 
  
 Section
14.01. Collateral Security. 
  
 (a) On the
Issue Date, the Company shall (i) enter into the Pledge Agreement and thereafter comply with the terms and provisions of such agreement and (ii) pledge the Pledged Securities to the Pledged Securities Intermediary for the benefit of the Trustee and
the ratable benefit of the Holders in such amount as will be sufficient upon receipt of scheduled interest and/or principal payments of such Pledged Securities to provide for payment in full of the first six scheduled interest payments due on the
Securities, but excluding the Liquidated Damages, if any. The Pledged Securities shall be pledged by the Company to the Pledged Securities Intermediary for the benefit of the Trustee and the ratable benefit of the Holders and shall be held by the
Pledged Securities Intermediary in the Pledge Account pending disposition pursuant to the Pledge Agreement. The Pledged Securities shall also secure the payment of the Principal Amount and Liquidated Damages, if any, due on the Securities subject to
the terms and conditions set forth in Section 13 of the Pledge Agreement. 
  
 (b) Each Holder, by its acceptance of a Security, consents and agrees to the terms of the Pledge Agreement (including, without limitation, the provisions providing for foreclosure and release of the Pledged
Securities) as such agreement may be in effect or may be amended from time to time in accordance with their terms, and authorizes and directs the Pledged Securities Intermediary and the Trustee to enter into the Pledge Agreement and to perform their
respective obligations and exercise their respective rights under such agreement in accordance therewith. The Company will do or cause to be done all such acts and things as may be necessary or reasonably requested by the Pledged Securities
Intermediary or the Trustee, or as may be required by the provisions of the Pledge Agreement, to assure and confirm to the Pledged Securities Intermediary and the Trustee the security interest in the Pledged Securities contemplated hereby, by the
Pledge Agreement or any part of such agreement, as from time to time constituted, so as to render the same available for the security and benefit of this Indenture and of the Securities secured hereby, according to the intent and purposes herein and
therein expressed. The Company shall take, or cause to be taken, upon request of the Pledged Securities Intermediary or the Trustee, any and all actions reasonably required to create and maintain, as security for the obligations of the Company under
this Indenture and the Securities, a valid, enforceable and perfected first priority Lien in and on all the Pledged Securities, in favor of the Pledged Securities Intermediary for the benefit of the Trustee and the ratable benefit of the Holders,
superior to and prior to the rights of third Persons and subject to no other Liens. 
  
 (c) The release of any portion of the Pledged Securities pursuant to the Pledge Agreement will not be deemed to impair the security under
this Indenture in contravention of the provisions hereof if and to the extent the Pledged Securities are released pursuant to this Indenture and the Pledge Agreement. To the extent applicable, the Company shall cause TIA Section 314(d) relating to
the release of property or securities from the Lien and 

  

 68 

 
security interest of the Pledge Agreement and relating to the substitution therefore of any property or securities to be subjected to the Lien and security
interest of the Pledge Agreement to be complied with. Any certificate or opinion required by TIA Section 314(d) may be made by an Officer of the Company, except in cases where TIA Section 314(d) requires that such certificate or opinion be made by
an independent Person, which Person shall be an independent engineer, appraiser or other expert selected by the Company. 
  
 (d) The Company shall cause TIA Section 314(b), relating to opinions of counsel regarding the Lien under the Pledge Agreement, to be
complied with. The Pledged Securities Intermediary and the Trustee may accept, to the extent permitted by Sections 4.4 and 7.6 as conclusive evidence of compliance with the foregoing provisions, the appropriate statements contained in such
instruments. 
  
 (e) The Pledged Securities
Intermediary and the Trustee may, in their sole discretion and without the consent of the Holders, on behalf of the Holders, take all reasonable actions in accordance with the Pledge Agreement, necessary or appropriate in order to (i) enforce any of
the terms of the Pledge Agreement and (ii) collect and receive any and all amounts payable in respect of the obligations of the Company under such agreement. The Pledged Securities Intermediary and the Trustee shall have power to institute and to
maintain such suits and proceedings as the they may reasonably deem expedient to preserve or protect their interests and the interests of the Holders in the Pledged Securities (including power to institute and maintain suits or proceedings to
restrain the enforcement of or compliance with any legislative or other governmental enactment, rule or order that may be unconstitutional or otherwise invalid if the enforcement of, or compliance with, such enactment, rule or order would impair the
security interest hereunder or be prejudicial to the interests of the Holders, the Pledged Securities Intermediary or of the Trustee). 
  

 69 

 IN WITNESS WHEREOF, the parties hereto have caused this Indenture to be duly executed as of the day and
year first above written. 
  

			
	OSCIENT PHARMACEUTICALS CORPORATION
		
	 By:
	 	/s/    STEPHEN COHEN
	 Name:
	 	Stephen Cohen
	 Title:
	 	Senior Vice President and CFO

  

			
	 U.S. BANK NATIONAL ASSOCIATION,
 as
Trustee

		
	 By:
	 	/s/    GEORGE H. DAVISON
	 Name:
	 	George H. Davison
	 Title:
	 	Officer

  

 70 

 EXHIBIT A 
  

FORM OF FACE OF SECURITY 
  
 [INCLUDE IF SECURITY IS A RESTRICTED SECURITY — THIS SECURITY (OR ITS PREDECESSOR) WAS ORIGINALLY ISSUED IN A TRANSACTION EXEMPT FROM
REGISTRATION UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND THIS SECURITY AND THE COMMON STOCK ISSUABLE UPON CONVERSION HEREOF MAY NOT BE OFFERED, SOLD OR OTHERWISE TRANSFERRED IN THE ABSENCE OF SUCH
REGISTRATION OR AN APPLICABLE EXEMPTION THEREFROM. EACH PURCHASER OF THIS SECURITY IS HEREBY NOTIFIED THAT THE SELLER OF THIS SECURITY MAY BE RELYING ON THE EXEMPTION FROM THE PROVISIONS OF SECTION 5 OF THE SECURITIES ACT PROVIDED BY RULE 144A
THEREUNDER. 
  
 THE HOLDER OF THIS SECURITY AGREES FOR THE BENEFIT
OF OSCIENT PHARMACEUTICALS CORPORATION THAT (A) PRIOR TO THE EXPIRATION OF THE HOLDING PERIOD APPLICABLE TO SALES OF THIS SECURITY UNDER RULE 144(K) UNDER THE SECURITIES ACT (OR ANY SUCCESSOR PROVISION), THIS SECURITY AND THE SHARES OF COMMON STOCK
ISSUABLE UPON CONVERSION HEREOF MAY BE OFFERED, RESOLD, PLEDGED OR OTHERWISE TRANSFERRED ONLY TO (I) OSCIENT PHARMACEUTICALS CORPORATION OR ANY SUBSIDIARY THEREOF, (II) TO A PERSON WHOM THE SELLER REASONABLY BELIEVES IS A QUALIFIED INSTITUTIONAL
BUYER (AS DEFINED IN RULE 144A UNDER THE SECURITIES ACT) IN A TRANSACTION MEETING THE REQUIREMENTS OF RULE 144A, (III) PURSUANT TO AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT PROVIDED BY RULE 144 THEREUNDER (IF AVAILABLE) OR (IV)
PURSUANT TO A REGISTRATION STATEMENT WHICH HAS BEEN DECLARED EFFECTIVE UNDER THE SECURITIES ACT, IN EACH CASE IN ACCORDANCE WITH ANY APPLICABLE SECURITIES LAWS OF ANY STATE OF THE UNITED STATES, AND (B) THE HOLDER WILL, AND EACH SUBSEQUENT HOLDER IS
REQUIRED TO, NOTIFY ANY PURCHASER OF THIS SECURITY OF THE RESALE RESTRICTIONS REFERRED TO IN CLAUSE (A) ABOVE. THIS LEGEND WILL BE REMOVED UPON THE EARLIER OF THE TRANSFER OF THIS SECURITY PURSUANT TO CLAUSE (A)(IV) ABOVE OR UPON ANY TRANSFER OF
THIS SECURITY UNDER RULE 144(K) UNDER THE SECURITIES ACT (OR ANY SUCCESSOR PROVISION). THE INDENTURE CONTAINS A PROVISION REQUIRING THE TRUSTEE TO REFUSE TO REGISTER THE TRANSFER OF THIS SECURITY IN VIOLATION OF THE FOREGOING RESTRICTION. IN
ADDITION, THE HOLDER HEREOF WILL NOT, DIRECTLY OR INDIRECTLY, ENGAGE IN ANY HEDGING TRANSACTIONS WITH REGARD TO THIS SECURITY OR THE COMMON STOCK ISSUABLE UPON THE CONVERSION HEREOF EXCEPT AS PERMITTED UNDER THE SECURITIES ACT (OR ANY SUCCESSOR
ACT). 
  

 [INCLUDE IF SECURITY IS A GLOBAL SECURITY — THIS SECURITY IS A GLOBAL SECURITY WITHIN THE
MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF A DEPOSITARY OR A NOMINEE THEREOF. THIS SECURITY MAY NOT BE EXCHANGED IN WHOLE OR IN PART FOR A SECURITY REGISTERED, AND NO TRANSFER OF THIS SECURITY IN WHOLE OR IN
PART MAY BE REGISTERED, IN THE NAME OF ANY PERSON OTHER THAN SUCH DEPOSITARY OR A NOMINEE THEREOF, EXCEPT IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE. 
  
 UNLESS THIS CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (“DTC”), A
NEW YORK CORPORATION, TO THE COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC
(AND ANY PAYMENT IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL IN AS MUCH AS THE REGISTERED
OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN.] 
  

 A-2 

 Oscient Pharmaceuticals Corporation 
  
 31⁄2% Senior Convertible Notes Due 2011 
  

					
	No. [    ]	 	CUSIP NO.                    	 	U.S. $[                 ]

  
 Oscient
Pharmaceuticals Corporation, a corporation duly organized and validly existing under the laws of the Commonwealth of Massachusetts (herein called the “Company”), which term includes any successor corporation under the Indenture
referred to on the reverse hereof), for value received hereby promises to pay to [    ], or registered assigns, the principal sum of [    ] United States Dollars ($  ) [INCLUDE IF SECURITY IS A
GLOBAL SECURITY — (which amount may from time to time be increased or decreased by adjustments made on the records of the Trustee, as custodian for the Depositary, in accordance with the rules and procedures of the Depositary)] on April 15,
2011 and to pay interest on said principal sum semi-annually on April 15 and October 15 of each year, commencing October 15, 2004 at the rate of 31⁄2% per annum to Holders of record on the immediately preceding April 1 and October 1,
respectively. Interest on this Security shall accrue from the most recent date to which interest has been paid, or if no interest has been paid, from May 10, 2004 until the Principal Amount is paid or duly made available for payment. Except as
otherwise provided in the Indenture, the interest payable on this Security pursuant to the Indenture on any April 15 or October 15 will be paid to the Person in whose name this Security (or one or more predecessor Securities) is registered at the
close of business on the Record Date, which shall be April 1 and October 1 (whether or not a Business Day) next preceding such April 15 or October 15, respectively. Payment of the principal of and interest accrued on this Security shall be made by
check mailed to the address of the Holder of this Security specified in the register of Securities, or, upon written application by a Holder of an aggregate Principal Amount of greater than U.S. $2 million to the Security Registrar setting forth
wire instructions not later than ten days prior to the relevant payment date, such Holder may receive payment by wire transfer in immediately available funds, in such lawful money of the United States of America as at the time of payment shall be
legal tender for the payment of public and private debts. 
  
 The
Issue Date of this Security is May 10, 2004. 
  
 The Holder of
this Security is entitled to the benefits of the Pledge Agreement, dated as of May 10, 2004, by and among the Company, U.S. Bank National Association, as the trustee (the “Trustee”), and U.S. Bank National Association, as securities
intermediary for the Trustee and the Holders from time to time (the “Pledged Securities Intermediary”) and pursuant to which the Company has placed in the Pledge Account cash or Pledged Securities sufficient to provide for the payment of
the first six interest payments on the Securities. 
  
 Reference
is made to the further provisions of this Security set forth on the reverse hereof, including, without limitation, provisions giving the Company the right to repurchase this Security commencing May 10, 2010, the right to convert this Security into
Common Stock of the Company and the right of the Holder of this Security to require the Company to repurchase this 

  

 A-3 

 
Security and upon certain events, in each case, on the terms and subject to the limitations referred to on the reverse hereof and as more fully specified in
the Indenture. Such further provisions shall for all purposes have the same effect as though fully set forth at this place. Capitalized terms used but not defined herein shall have such meanings as are ascribed to such terms in the Indenture.

  
 This Security shall be deemed to be a contract made under the
laws of the State of New York, and for all purposes shall be construed in accordance with and governed by the laws of said State. 
  
 This Security shall not be valid or become obligatory for any purpose until the certificate of authentication hereon shall have been manually signed by
the Trustee or a duly authorized authenticating agent under the Indenture. 
  
 IN WITNESS WHEREOF, the Company has caused this instrument to be duly executed. 
  

			
	OSCIENT PHARMACEUTICALS CORPORATION
		
	By:	 	 
	 Authorized Signatory

  

 A-4 

 EXHIBIT B 
  

FORM OF REVERSE OF SECURITY 
  
 This Security is one of a duly authorized issue of Securities of the Company, designated as its 31⁄2% Senior Convertible Notes Due 2011 (the
“Securities”), all issued or to be issued under and pursuant to an Indenture, dated as of May 10, 2004 (the “Indenture”), between the Company and U.S. Bank National Association (the “Trustee”), to
which Indenture and all indentures supplemental thereto reference is hereby made for a description of the rights, limitations of rights, obligations, duties and immunities thereunder of the Trustee, the Company and the Holders of the Securities.

  
 The indebtedness evidenced by the Securities is unsecured and
unsubordinated senior indebtedness of the Company and ranks equally with the Company’s other unsecured and unsubordinated senior indebtedness, except as provided in Paragraph 6 hereof. 
  
 1. Redemption at the Option of the Company. No
sinking fund is provided for the Securities. The Securities are redeemable as a whole, or from time to time in part, at any time commencing on May 10, 2010 at the option of the Company at a redemption price (the “Redemption Price”)
equal to 100%, expressed as a percentage of the Principal Amount of Securities to be redeemed, together with accrued and unpaid interest and Liquidated Damages, if any, to, but excluding, the Redemption Date. 
  
 2. Repurchase by the Company at the Option of the Holder
Upon a Fundamental Change. Subject to the terms and conditions of the Indenture, the Company shall become obligated, at the option of the Holder, to repurchase the Securities if a Fundamental Change occurs at any time prior to the Stated
Maturity at 100% of the Principal Amount plus accrued and unpaid interest and Liquidated Damages, if any, to, but excluding, the Fundamental Change Repurchase Date (the “Fundamental Change Repurchase Price”), which Fundamental
Change Repurchase Price will be paid in cash; provided that if a Fundamental Change results from a Change of Control Event, the Company may elect, subject to the satisfaction of certain conditions described in the Indenture, to pay all or a portion
of the Fundamental Change Repurchase Price in Common Stock or a combination of cash and Common Stock; and provided, further, that the “Fundamental Change Repurchase Price” shall include any Make-Whole Premium required by the terms
of the Indenture. The number of shares of Common Stock a Holder will receive will equal the quotient obtained by dividing (i) the portion of the Fundamental Change Repurchase Price to be paid in shares of Common Stock by (ii) 97% of the average
Closing Price of the shares of Common Stock for the five Trading Day period ending on the second Business Day immediately preceding the Fundamental Change Repurchase Date, subject to adjustment as described in the Indenture. Notwithstanding the
foregoing, a Holder will not have the right to require the Company to repurchase the Securities upon a Change of Control Event constituting a Fundamental Change if the Closing Price per share of the Company’s Common Stock for any five Trading
Days within the period of 10 consecutive Trading Days ending immediately after the later of the Change of Control Event and the public announcement of the Change of Control Event equals or exceeds 110% of the Conversion Price of the Securities in
effect on each of those five Trading Days. 
  

 3. Withdrawal of Fundamental Change Repurchase Notice. Holders have the right to
withdraw, in whole or in part, any Fundamental Change Repurchase Notice, by delivering to the Paying Agent a written notice of withdrawal in accordance with the provisions of the Indenture. 
  
 4. Payment of Redemption Price and Fundamental Change
Repurchase Price. If cash (and/or Common Stock, if permitted under the Indenture) sufficient to pay the Redemption Price or Fundamental Change Repurchase Price as the case may be, of all Securities or portions thereof to be redeemed or
repurchased on a Redemption Date or on a Fundamental Change, as the case may be, is deposited with the Paying Agent on the Business Day following the Redemption Date or the Fundamental Change Repurchase Date, as the case may be, the Securities to be
redeemed or repurchased will cease to be outstanding and interest and Liquidated Damages, if any, will cease to accrue on such Securities (or portions thereof) immediately after such Redemption Date or Fundamental Change Repurchase Date, as the case
may be, and the Holder thereof shall have no other rights as such (other than the right to receive the Redemption Price or Fundamental Change Repurchase Price as the case may be) upon surrender of such Security. 
  
 5. Conversion. Subject to the terms and conditions of
the Indenture, a Holder may convert each of its Securities into shares of the Company’s common stock at an initial conversion rate of 150.5571 shares per $1,000 Principal Amount of Securities (the “Conversion Rate”), at any time prior
to the close of business on April 14, 2011. The Conversion Rate in effect at any given time is subject to adjustment. A Holder may convert fewer than all of such Holder’s Securities so long as the Securities converted are an integral multiple
of $1,000 principal amount. Holders will not receive any cash payment representing accrued and unpaid interest or Liquidated Damages, if any, upon conversion of a Security. Accrued and unpaid interest and Liquidated Damages, if any, will be deemed
paid in full rather than canceled, extinguished or forfeited; provided, that if this Security shall be surrendered for conversion during the period from close of business on any Record Date for the payment of interest through the close of business
on the Business Day next preceding the following Interest Payment Date, such Security (or portion thereof being converted) must be accompanied by an amount, in funds acceptable to the Company, equal to the interest payable on such Interest Payment
Date on the Principal Amount being converted; provided, however, that no such payment shall be required if there shall exist at the time of conversion a default in the payment of interest on the Securities. 
  
 6. Pledge Agreement. The Company has entered into the
Pledge Agreement and purchased and pledged to the Trustee for its benefit and the ratable benefit of the Holders of the Securities the Pledged Securities in an amount sufficient upon receipt of scheduled interest and principal payments on such
Pledged Securities to provide for the payment in full of the first six scheduled interest payments (up to and including the interest payments due on April 15, 2007), but no Liquidated Damages, if any, on the Notes when due. The Pledged Securities
will be pledged by the Company to the Trustee for its benefit and the ratable benefit of the Holders 

  

 B-2 

 
and will be held by the Trustee in the Pledged Account pending disbursement pursuant to the Pledge Agreement. 
  
 [INCLUDE IF SECURITY IS A GLOBAL SECURITY — In the event of a
deposit or withdrawal of an interest in this Security, including an exchange, transfer, repurchase or conversion of this Security in part only, the Trustee, as custodian of the Depositary, shall make an adjustment on its records to reflect such
deposit or withdrawal in accordance with the rules and procedures of the Depositary.] 
  
 [INCLUDE IF SECURITY IS A RESTRICTED SECURITY — Subject to certain limitations in the Indenture, at any time when the Company is not subject to Section 13 or 15(d) of the United States Securities Exchange
Act of 1934, as amended, upon the request of a Holder of a Restricted Security, the Company will promptly furnish or cause to be furnished Rule 144A Information (as defined below) to such Holder of Restricted Securities, or to a prospective
purchaser of any such security designated by any such Holder, to the extent required to permit compliance by any such Holder with Rule 144A under the Securities Act of 1933, as amended (the “Securities Act”). “Rule 144A
Information” shall be such information as is specified pursuant to Rule 144A(d)(4) under the Securities Act (or any successor provision thereto).] 
  
 If an Event of Default shall occur and be continuing, the Principal Amount plus accrued and unpaid interest and Liquidated Damages, if any, through such
date on all the Securities may be declared due and payable in the manner and with the effect provided in the Indenture. 
  
 The Indenture permits, with certain exceptions as therein provided, the amendment thereof and the modification of the rights and obligations of the
Company and the rights of the Holders of the Securities under the Indenture at any time by the Company and the Trustee with the consent of the Holders of not less than a majority in aggregate Principal Amount of the Outstanding Securities. The
Indenture also contains provisions permitting the Holders of specified percentages in aggregate Principal Amount of the Outstanding Securities, on behalf of the Holders of all the Securities, to waive compliance by the Company with certain
provisions of the Indenture and certain past defaults under the Indenture and their consequences. Any such consent or waiver by the Holder of any provision of or applicable to this Security shall be conclusive and binding upon such Holder and upon
all future Holders of this Security and of any Security issued upon the registration of transfer hereof or in exchange herefor or in lieu hereof, whether or not notation of such consent or waiver is made upon this Security. 
  
 As provided in and subject to the provisions of the Indenture, the Holder of
this Security shall not have the right to institute any proceeding with respect to the Indenture or for the appointment of a receiver or trustee or for any other remedy thereunder, unless such Holder shall have previously given the Trustee written
notice of a continuing Event of Default with respect to the Securities, the Holders of not less than 25% in aggregate Principal Amount of the Outstanding Securities shall have made written request to the Trustee to institute proceedings in respect
of such Event of Default as Trustee and offered the Trustee reasonable indemnity satisfactory to it, the Trustee shall not have received from the Holders of a majority in Principal Amount of Outstanding Securities a direction inconsistent with such
request, and the Trustee 

  

 B-3 

 
shall have failed to institute any such proceeding, for 60 days after receipt of such notice, request and offer of indemnity. The foregoing shall not apply
to any suit instituted by the Holder of this Security for the enforcement of any payment of said principal hereof or interest hereon on or after the respective due dates expressed herein or for the enforcement of any conversion right. 
  
 No reference herein to the Indenture and no provision of this Security or of
the Indenture shall alter or impair the obligation of the Company, which is absolute and unconditional, to pay the Principal Amount or Fundamental Change Repurchase Price of or interest and Liquidated Damages, if any, on, this Security at the times,
place and rate, and in the coin or currency, herein prescribed. 
  
 As provided in the Indenture and subject to certain limitations therein set forth, the transfer of this Security is registrable in the Security Register, upon surrender of this Security for registration of transfer at the office or agency
of the Company in The City of New York, duly endorsed by, or accompanied by a written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed by, the Holder hereof or his attorney duly authorized in
writing, and thereupon one or more new Securities, of authorized denominations and for the same aggregate Principal Amount, will be issued to the designated transferee or transferees. 
  
 The Securities are issuable only in registered form in denominations of $1,000 and any integral multiple of $1,000 above
that amount, as provided in the Indenture and subject to certain limitations therein set forth. Securities are exchangeable for a like aggregate Principal Amount of Securities of a different authorized denomination, as requested by the Holder
surrendering the same. 
  
 No service charge shall be made for any
such registration of transfer or exchange, but the Company may require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 
  
 Prior to due presentment of this Security for registration of transfer, the Company, the Trustee and any agent of the
Company or the Trustee may treat the Person in whose name this Security is registered as the owner hereof for all purposes, whether or not this Security be overdue, and neither the Company, the Trustee nor any such agent shall be affected by notice
to the contrary. 
  
 This Security shall be governed by and
construed in accordance with the laws of the State of New York. 
  
 All terms used in this Security that are defined in the Indenture shall have the meanings assigned to them in the Indenture. 
  

 B-4 

 ASSIGNMENT FORM 
  
 If you want to assign this Security, fill in the form below and have your signature guaranteed: 
  
 I or we assign and transfer this Security to: 
  
                                       
                                        
                                        
                                        
                                        
                                        
                    
  
                                       
                                        
                                        
                                        
                                        
                                        
                    
  
                                       
                                        
                                        
                                        
                                        
                                        
                    
 (Print or type name, address and zip
code and social security or tax ID number of assignee) 
  
 and irrevocably appoint
                                        
                                        
             agent to transfer this Security on the books of the Company. The agent may substitute another to act for him. 
  

			
	 Date:
                                
	  	 Signed:                                

	
	 (Sign exactly as your name appears on the other side of this Security)

	
	 Signature Guarantee:________________________________________________________

  
 Note: Signatures must be guaranteed by
an “eligible guarantor institution” meeting the requirements of the Security Registrar, which requirements include membership or participation in the Security Transfer Agent Medallion Program (“STAMP”) or such other
“signature guarantee program” as may be determined by the Security Registrar in addition to, or in substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934, as amended. 
  

 B-5 

 In connection with any transfer of this Security occurring prior to the date which is the earlier of (i)
the date of the declaration by the Commission of the effectiveness of a registration statement under the Securities Act, as amended (the “Securities Act”), covering resales of this Security (which effectiveness shall not have been
suspended or terminated at the date of the transfer) and (ii) the second anniversary of the Issue Date set forth on the face of this Security, the undersigned confirms that it has not utilized any general solicitation or general advertising in
connection with the transfer and that this Security is being transferred: 
  
 [Check One] 
  

					
	 (1)
	 	 ̈	  	to the Company or a subsidiary thereof; or
			
	 (2)
	 	 ̈	  	to a “Qualified Institutional Buyer” pursuant to and in compliance with Rule 144A under the Securities Act; or
			
	 (3)
	 	 ̈	  	pursuant to the exemption from registration provided by Rule 144 under the Securities Act.

  
 Unless one of the above boxes is
checked, the Trustee will refuse to register any of the Securities evidenced by this certificate in the name of any Person other than the registered Holder thereof, provided that if box (3) is checked, the Company may require, prior to registering
any such transfer of the Securities, in its sole discretion, such legal opinions, certifications and other information as the Company may reasonably request to confirm that such transfer is being made pursuant to an exemption from, or in a
transaction not subject to, the registration requirements of the Securities Act. 
  
 If none of the foregoing boxes is checked, the Trustee or Security Registrar shall not be obligated to register this Security in the name of any Person other than the Holder hereof unless and until the conditions to
any such transfer of registration set forth herein and in Section 3.09 of the Indenture shall have been satisfied. 
  

									
					
	Date:	  	 	 	 	 	Signed:	 	 
	 	  	 	 	 	 	 	 	(Sign exactly as your name appears on the other side of this Security)

  

									
	 Signature Guarantee:_____________________________________________________________

  
 Note: Signatures must be guaranteed by
an “eligible guarantor institution” meeting the requirements of the Security Registrar, which requirements include membership or participation in the Security Transfer Agent Medallion Program (“STAMP”) or such other
“signature guarantee program” as may be determined by the Security Registrar in addition to, or in substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934, as amended. 
  

 B-6 

 TO BE COMPLETED BY PURCHASER IF (2) ABOVE IS CHECKED 
  
 The undersigned represents and warrants that it is purchasing this Security
for its own account or an account with respect to which it exercises sole investment discretion and that it and any such account is a “qualified institutional buyer” within the meaning of Rule 144A under the Securities Act and is aware
that the sale to it is being made in reliance on Rule 144A and acknowledges that it has received such information regarding the Company as the undersigned has requested pursuant to Rule 144A or has determined not to request such information and that
it is aware that the transferor is relying upon the undersigned’s foregoing representations in order to claim the exemption from registration provided by Rule 144A. 
  

									
					
	 Date:
	 	 	 	 	 	 Signed:
	 	 
				
	 NOTICE: To be executed by an executive officer.
	 	 	 	 	 	 

  

 B-7 

 CONVERSION NOTICE 
  

If you want to convert this Security into Common Stock of the Company, check the box: 
  
 To convert only part of this Security, state the Principal Amount to be converted (which must be $1,000 or an integral
multiple of $1,000): 
  
 $                                      
                                       
  
 If you want the stock certificate made out in another person’s name,
fill in the form below: 
  
                                       
                                        
                                        
                                        
                                        
                                        
                    
 (Insert other
person’s social security or tax ID no.) 
  
                                       
                                        
                                        
                                        
                                        
                                        
                    
  
                                       
                                        
                                        
                                        
                                        
                                        
                    
  
                                       
                                        
                                        
                                        
                                        
                                        
                    
 (Print or type other
person’s name, address and zip code) 
  

									
					
	 Date:
	 	 	 	 	 	 Signed:
	 	 

									
	
	(Sign exactly as your name appears on the other side of this Security)

  

									
	 Signature Guarantee:_____________________________________________________________

  
 Note: Signatures must be guaranteed by
an “eligible guarantor institution” meeting the requirements of the Security Registrar, which requirements include membership or participation in the Security Transfer Agent Medallion Program (“STAMP”) or such other
“signature guarantee program” as may be determined by the Security Registrar in addition to, or in substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934, as amended. 
  

 B-8 

 EXHIBIT C 
  

FORM OF TRUSTEE’S CERTIFICATE OF AUTHENTICATION 
  
 U.S. Bank National Association, as Trustee, certifies that this is one of the Securities referred to in the within-mentioned Indenture. 
  

									
	Dated: ________________	 	 	 	 U.S. BANK NATIONAL ASSOCIATION, as Trustee

				
	 	 	 	 	By:	 	 
	 	 	 	 	 	 	 Authorized Signatory

  

 EXHIBIT D 
  

FORM OF FUNDAMENTAL CHANGE REPURCHASE NOTICE 
  
                                 , 20    

  
 __________________________ 
  
 __________________________ 
  
 __________________________ 
  
 __________________________ 
  
 Attention: [Institutional Trust Services] 
  

	 	Re:	Oscient Pharmaceuticals Corporation (the “Company”)  

 31⁄2% Senior Convertible Notes Due 2011 
  
 This is a Fundamental Change Repurchase Notice as defined in Section 11.08 of the Indenture dated as of May 10, 2004 (the “Indenture”) between the Company and U.S. Bank National Association, as Trustee.
Terms used but not defined herein shall have the meanings ascribed to them in the Indenture. 
  
 Certificate No(s). of Securities:
                                        
                                        
                                 
  
 I intend to deliver the following aggregate Principal Amount of Securities
for purchase by the Company pursuant to Section 11.08 of the Indenture (in multiples of $1,000): 
  
 $                                      
                                        
           
  
 I hereby agree that the Securities will be purchased as of the Fundamental Change Repurchase Date pursuant to the terms and conditions thereof and of the Indenture. 
  
 Signed:PLEDGE AGREEMENT DATED AS OF MAY 10, 2004

 Exhibit 4.2 
  

PLEDGE AGREEMENT 
  
 PLEDGE AGREEMENT, dated as of May 10, 2004 (this “Agreement”), by and among Oscient Pharmaceuticals Corporation, a corporation duly
organized and existing under the laws of the Commonwealth of Massachusetts (the “Grantor”), having its principal office at 100 Beaver Street, Waltham, MA 02453, and U.S. Bank National Association (“U.S. Bank”), a
national banking association, (i) in its capacity as trustee (the “Trustee”) for the holders (the “Holders”) of the Securities (as hereinafter defined) issued by the Grantor under the Indenture referred to below and
(ii) in its individual capacity, as securities intermediary (in such capacity, the “Pledged Securities Intermediary”) at its office at One Federal Street, 3rd Floor, Boston, Massachusetts 02110 (the “Account Office”) with respect to the Pledge Account (as hereinafter defined). Capitalized terms used
herein and not otherwise defined herein shall have the meanings given to such terms in the Indenture. 
  
 RECITALS 
  
 The Grantor and the Trustee have entered into that certain Indenture dated as of the date hereof (as amended, restated, supplemented or otherwise modified from time to time, the “Indenture”), pursuant to which the Grantor
is issuing on the date hereof $125,000,000 in aggregate principal amount of its 31⁄2% Senior Subordinated Convertible Notes due 2011 (the “Securities”). 
  
 Subject to the terms of this Agreement, the Pledged Securities Intermediary has established for the Grantor, as beneficial
owner, a securities account (the “Pledge Account”) at the Account Office, registered in the name of the Trustee, as entitlement holder, and designated as Account No. 785658010, Reference: U.S. Bank Pledge Account for the benefit of
the Holders of Oscient 31⁄2% Senior Subordinated Convertible Securities. 
  
 The Grantor has agreed to purchase or cause the purchase of security entitlements with respect to the U. S. Government Securities identified by CUSIP number in Schedule I hereto (such security entitlements being,
collectively, the “Initial Pledged Securities,” together with the Additional Pledged Securities (as defined below), the “Pledged Securities”), for the account of the Pledged Securities Intermediary for credit to the
Pledge Account, in an amount that will be sufficient, upon receipt of the scheduled interest and principal payments in respect thereof, to provide for the payment of the first six scheduled interest payments due on the Securities (up to and
including the interest payment due on April 15, 2007, but excluding Liquidated Damages, if any). 
  
 To secure the obligations of the Grantor under the Indenture and the Securities to pay in full each of the first six scheduled interest payments on the
Securities and to pay the principal and interest on the Securities and all other amounts payable by the Grantor under the Indenture in the event that the Securities or any principal thereof becomes due and payable prior to such time as the first six
scheduled interest payments thereon shall have been paid in full (collectively, the “Obligations”), the Grantor has agreed (i) to grant to the Trustee, for its benefit and the ratable 

  

 
benefit of the Holders of the Securities, a security interest in the Pledge Account and all cash, Pledged Securities and other Collateral (as hereinafter
defined) from time to time deposited therein or credited thereto and (ii) to execute and deliver this Agreement in order to secure the payment and performance by the Grantor of all the Obligations. 
  
 It is a condition precedent to the purchase of the Securities by the initial
Holders thereof that the Grantor shall have granted the security interests contemplated by this Agreement. 
  
 Unless otherwise defined herein or in the Indenture, terms used herein that are defined in Article 8 or 9 of the Uniform Commercial Code as in effect in
the State of New York (the “UCC”) are used herein as therein defined. 
  
 NOW, THEREFORE, for and in consideration of the mutual promises herein contained, and in order to induce the initial Holders to purchase the Securities, the Grantor hereby agrees with the Trustee, for the benefit of
the Trustee and for the ratable benefit of the Holders of the Securities, and with the Pledged Securities Intermediary, as follows: 
  
 SECTION 1. Grant of Security Interest. The Grantor hereby grants to the Trustee, for its benefit and for the ratable benefit of the Holders of the
Securities, a security interest in and to all of the Grantor’s right, title and interest in, to and under the following, in each case whether now owned or hereafter acquired, wherever located and whether now or hereafter existing (hereinafter
collectively referred to as the “Collateral”): 
  
 (a) the Pledge Account; 
  
 (b) all cash or credit
balances from time to time deposited in or credited to the Pledge Account; 
  
 (c) the Pledged Securities and all other financial assets (including certificated and uncertificated securities) and security entitlements from time to time deposited in, credited to, or created or otherwise carried
in the Pledge Account; 
  
 (d) all interest, dividends, cash,
instruments and other property from time to time received, receivable or otherwise distributed in respect of or in exchange for any or all of the Collateral; 
  
 (e) all securities (whether certificated or uncertificated) or other financial assets, security entitlements, securities accounts, accounts, general
intangibles, instruments, documents, cash or deposit accounts representing or evidencing any or all of the Collateral; and 
  
 (f) to the extent not covered by clauses (a) through (e) above, all proceeds of any and all of the foregoing Collateral (including, without limitation,
proceeds that constitute property of the types described in clauses (a) through (e) above). 
  

 2 

 SECTION 2. Secured Obligations. This Agreement and the grant of a security interest in the
Collateral secure the prompt and complete payment and performance when due (whether at stated maturity, by acceleration, upon redemption or otherwise) of all Obligations now or hereafter existing, whether for principal, interest, fees, expenses,
indemnities or otherwise, and all obligations of the Grantor now or hereafter existing under this Agreement (all such Obligations and such other obligations being, collectively, the “Secured Obligations”). Without limiting the
generality of the foregoing, this Agreement and the grant of a security interest in the Collateral hereunder secure, to the fullest extent permitted by applicable law, the payment of all amounts that constitute part of the Secured Obligations and
that would be owed by the Grantor to the Trustee or the Holders under the Securities or the Indenture but for the fact that they are unenforceable or not allowable due to the existence of a bankruptcy, reorganization or similar proceeding involving
the Grantor. 
  
 SECTION 3. Maintaining the Pledge Account.
Prior to or concurrently with the execution and delivery hereof and for so long as any Secured Obligation shall remain outstanding, 
  
 (a) the Trustee shall establish and maintain (and the Pledged Securities Intermediary shall maintain and administer in accordance with this Agreement) the
Pledge Account with the Pledged Securities Intermediary at the Account Office in accordance with the terms of this Agreement. The Pledge Account shall at all times be under the sole dominion and control of, and shall at all times be segregated from
any other custodial, collateral or other accounts maintained by, or under the dominion and control of, the Trustee; 
  
 (b) it shall be a term and condition of the Pledge Account, notwithstanding any term or condition to the contrary in any other agreement relating to the
Pledge Account, and except as otherwise provided by the provisions of Section 5 and Section 15.9 of this Agreement, that no Collateral (including proceeds thereof) shall be paid or released from the Pledge Account to or for the account of, or
withdrawn by or for the account of, and no entitlement orders with respect to any of the Collateral shall be given to the Pledged Securities Intermediary by, the Grantor or any other Person other than the Trustee as provided herein; 
  
 (c) subject to the provisions of this Agreement, the Pledge Account shall be
registered in the name of the Trustee on the books and records of the Pledged Securities Intermediary, the Trustee shall be identified on such books and records as the entitlement holder with respect to all security entitlements in all financial
assets from time to time held in or credited to the Pledge Account, and the Trustee shall have the sole right to (i) deliver entitlement orders with respect to the Pledge Account and any Collateral from time to time credited thereto, deposited
therein or represented thereby or (ii) make withdrawals from the Pledge Account or otherwise exercise any other rights with respect to any Collateral from time to time credited thereto or on deposit therein; and 
  
 (d) the Pledge Account shall be subject to such applicable laws, and such
applicable regulations of any appropriate banking or governmental authority, as may now or hereafter be in 

  

 3 

 
effect, including without limitation any applicable regulations of the Board of Governors of the Federal Reserve System. 
  
 SECTION 4. Acquisition of Pledged Securities for Credit to the Pledge
Account. 
  
 (a) On or prior to the date hereof, the Grantor
shall purchase or cause the purchase of the Pledged Securities for the account of the Pledged Securities Intermediary for credit to the Pledge Account. 
  
 (b) Upon transfer or credit of the Pledged Securities to the Pledged Securities Intermediary, as confirmed to the Pledged Securities Intermediary by the
Federal Reserve Bank of New York or another securities intermediary at which the Pledged Securities Intermediary maintains a securities account, the Pledged Securities Intermediary shall make appropriate book entries indicating that the Pledged
Securities have been credited to and are held in the Pledge Account. 
  
 SECTION 5. Disbursements From the Pledge Account; Transfers of Additional Amounts to the Pledge Account. 
  
 (a) At least three Business Days prior to the due date of any of the first six scheduled interest payments on the Securities, the Grantor may, pursuant to
written instructions given by the Grantor to the Trustee (each an “Issuer Order”), instruct the Trustee to direct the Pledged Securities Intermediary to release from the Pledge Account, and pay to the Holders of the Securities as of
the applicable Record Date, proceeds of the Pledged Securities sufficient to provide for payment in full of such interest then due on the Securities. Upon receipt of an Issuer Order, the Trustee will direct the Pledged Securities Intermediary to
sell Pledged Securities sufficient to provide for payment in full of such interest then due on the Securities and to release funds from (and to the extent of) proceeds of the Pledged Securities in the Pledge Account in an amount sufficient to
provide for the payment in full of such interest then due on the Securities, as instructed in such Issuer Order, and to transfer such funds to the Holders of the Securities in accordance with the payment provisions of the Indenture. Nothing in this
Section 5 shall affect the Trustee’s rights to direct the application of the Collateral to the payment of amounts due on the Securities upon acceleration thereof in accordance with the terms of the Indenture. 
  
 (b) If the Grantor makes all or any portion of any interest payment for which
the Collateral is security from a source of funds other than the Pledge Account (“Grantor Funds”), the Grantor may, after payment in full of such interest payment, instruct the Trustee, pursuant to an Issuer Order, to direct the
Pledged Securities Intermediary to release to the Grantor, or to another party designated by the Grantor in such Issuer Order (the “Grantor’s Designee”), proceeds from the Pledge Account in an amount that, in the discretion of
the Grantor, is less than or equal to the amount of Grantor Funds applied to such interest payment; provided that, after giving effect to such release, the scheduled interest and principal payments in respect of the Pledged Securities remaining in
the Pledge Account, together with any cash remaining in the Pledge Account, equal or exceed the amount necessary to provide for the timely payment in full of interest on the Securities for as many of the first six scheduled interest payments as
shall then 

  

 4 

 
remain. Upon (i) receipt by the Trustee of such Issuer Order and (ii) confirmation by the Trustee of the payment in full of such interest payment (from such
Grantor Funds and, if necessary, additional funds released from the Pledge Account in accordance with Section 5(a)), the Trustee shall direct the Pledged Securities Intermediary to release funds from (and to the extent of) proceeds of the Pledged
Securities in the Pledge Account and to transfer such funds to the Grantor or the Grantor’s Designee, as the case may be, as instructed in such Issuer Order as soon as practicable after such conditions are satisfied. 
  
 (c) If at any time the scheduled interest and principal payments in respect
of the Pledged Securities then credited to the Pledge Account, together with any cash then held in the Pledge Account, exceed 100% of the amount necessary (which shall be certified in writing by the principal executive, financial or accounting
officer of the Grantor in accordance with, and meeting the requirements of, the provisions of Section 314(d) of the Trust Indenture Act of 1939, as amended (“TIA”) or, if such amount, together with all other amounts disbursed from
the Pledge Account in the preceding 12 month period, equals or exceeds $100,000, by a nationally recognized firm of independent accountants selected by the Grantor and delivered to the Trustee) to provide for the payment in full, when due, of the
first six scheduled interest payments on the Securities (or such number of the first six scheduled interest payments on the Securities as shall then remain, as the case may be), the Grantor may instruct the Trustee, pursuant to an Issuer Order, to
direct the Pledged Securities Intermediary to release any such excess amount to the Grantor or to the Grantor’s Designee. Upon receipt of such Issuer Order (which shall be accompanied by a certificate in accordance with, and meeting the
requirements of, the provisions of Section 314(d) of the TIA or, if the amount to be released from the pledge, together with all other amounts disbursed from the Pledge Account in the preceding 12 month period, equals or exceeds $100,000, by a
certificate of such nationally recognized firm of independent accountants stating that the scheduled interest and principal payments in respect of the Pledged Securities credited to the Pledge Account, together with any cash held in the Pledge
Account, in each case after giving effect to such release, equal or exceed 100% of the amount necessary to provide for the payment in full, when due, of such remaining scheduled interest payments on the Securities), the Trustee shall instruct the
Pledged Securities Intermediary to release funds from (and to the extent of) proceeds of such Pledged Securities in accordance with such Issuer Order and the accompanying certificate and to transfer such funds to the Grantor or the Grantor’s
Designee, as the case may be; provided, however, that before such funds may be transferred hereunder, if the certificate required by this sentence is executed by the Grantor rather than by a nationally recognized firm of independent accountants
selected by the Grantor, the mathematical accuracy of the computations set forth in such certificate shall be verified by a verification agent with assets of at least $50 million selected by the Grantor (the “Verification Agent”).

  
 (d) Upon the release of any Collateral from the Pledge Account
in accordance with the terms of this Section 5, whether upon release of proceeds of Collateral to the Holders as payment of interest or upon release of proceeds of Collateral to the Grantor or the Grantor’s Designee as provided in Section 5(b)
or Section 5(c), the security interest evidenced by this Agreement in such released Collateral will automatically terminate and be of no further force and effect. 
  

 5 

 (e) At least three Business Days prior to the due date of each of the first six scheduled interest
payments on the Securities, the Grantor shall give the Trustee notice (by Issuer Order) as to whether such interest payment will be made pursuant to Section 5(a) or 5(b) above and the respective amounts of interest that will be paid from the Pledge
Account and from Grantor Funds (it being understood that the failure by the Grantor to provide an Issuer Order shall not constitute an Event of Default). Any Grantor Funds to be used to make any interest payment (or portion thereof) shall be
delivered to the Trustee, in immediately available funds, prior to 11:00 a.m. (New York City time) on such interest payment date. If no such notice is given or such Grantor Funds have not been so delivered, the Trustee will act pursuant to Section
5(a) above as if it had received an Issuer Order pursuant thereto for the payment in full of the interest then due from the proceeds of Pledged Securities in the Pledge Account. 
  
 (f) If on any interest payment date there are insufficient proceeds of Pledged Securities in the Pledge Account to make the
scheduled payment of interest due on such date (after taking into account any Grantor Funds delivered to the Trustee as provided in Section 5(b) above), the Trustee shall direct the Pledged Securities Intermediary to liquidate Collateral in the
Pledge Account to the extent necessary to pay, in full, such scheduled payment of interest. 
  
 (g) Nothing contained in this Agreement (including without limitation the provisions hereof regarding the delivery of Issuer Orders by the Grantor to the Trustee) shall (i) afford the Grantor any right to issue
entitlement orders to the Pledged Securities Intermediary or any other Person with respect to the Pledge Account or any security entitlement in respect of the Pledged Securities, or otherwise afford the Grantor control of the Pledge Account or any
such security entitlement, or (ii) otherwise give rise to any rights of the Grantor with respect to the Pledge Account, the Pledged Securities, or any security entitlement thereto, other than the Grantor’s rights under this Agreement as the
beneficial owner of Collateral pledged to and subject to the exclusive dominion and control (subject to the Trustee’s obligations to comply with Sections 5(a) through (f) and Section 15.9 hereof) of the Trustee in its capacity as such (and not
as a securities intermediary). The Grantor acknowledges, confirms and agrees that the Trustee holds a security interest in the Pledged Securities solely as Trustee for the Holders of the Securities and not as a securities intermediary. 

 
 (h) Anything contained herein to the contrary notwithstanding, prior to
any release of any Collateral to the Grantor or the Grantor’s Designee, the Grantor shall deliver to the Trustee such certificates, opinions or other documents as may be required by the Indenture or the TIA in connection with such release and
shall otherwise comply with the requirements of the Indenture and the TIA applicable thereto. 
  
 (i) If at any time the Grantor is obligated to pay any amount to the Trustee or the Pledged Securities Intermediary pursuant to the terms of this Agreement and the Trustee charges such amount against the Pledge
Account with the result that the scheduled interest and principal payments in respect of the Pledged Securities then credited to the Pledge Account, together with any cash then held in the Pledge Account, are less than 100% of the amount necessary
to provide for the payment in full, when due, of the first six scheduled interest payments on the Securities 

  

 6 

 
(or such number of the first six scheduled interest payments on the Securities as shall then remain, as the case may be), the Grantor shall deposit cash into
the Pledge Account in the amount of such deficiency and shall deliver to the Trustee a certificate signed by its principal executive, financial or accounting officer stating that the scheduled interest and principal payments in respect of the
Pledged Securities credited to the Pledge Account, together with any cash held in the Pledge Account, in each case after giving effect to such deposit by the Grantor, equal or exceed 100% of the amount necessary to provide for the payment in full,
when due, of such remaining scheduled interest payments on the Securities and the Verification Agent, or, at the option of the Grantor, a nationally recognized firm of independent accountants selected by the Grantor, shall verify the mathematical
accuracy of the computations set forth in such certificate. 
  
 (j) Neither the Trustee nor the Pledged Securities Intermediary shall be liable for any disbursement made or other action taken in accordance with an Issuer Order. In no event shall either of the Pledged Securities Intermediary or the
Trustee in its role hereunder be liable for any special, indirect or consequential loss or damage of any kind whatsoever (including but not limited to lost profits), except as a result of its gross negligence or willful misconduct. 
  
 SECTION 6. Securities Intermediary. U.S. Bank, as Pledged Securities
Intermediary, hereby represents and warrants to, and agrees with the Grantor and the Trustee, as follows: 
  
 (a) It is a securities intermediary as of the date hereof and, for so long as this Agreement remains in effect and U.S. Bank is acting as the Pledged
Securities Intermediary hereunder, it shall remain a securities intermediary and shall at all times act in such capacity with respect to the Trustee, the Pledge Account and all other Collateral. 
  
 (b) The Pledge Account is and will be maintained as a securities account.

  
 (c) Each item of property (whether cash, certificated or
uncertificated securities, security certificates, security entitlements or any other property whatsoever) credited to the Pledge Account shall be treated as a financial asset. 
  
 (d) All financial assets in registered form or payable to, or to the order of, any Person and credited to the Pledge Account
shall be registered in the name of, payable to or to the order of, or endorsed to, the Pledged Securities Intermediary, and in no case during the term of this Agreement will any financial asset credited to the Pledge Account be registered in the
name of, payable to or to the order of, or endorsed to, the Grantor, except to the extent the foregoing have been subsequently endorsed by the Grantor to the Pledged Securities Intermediary or in blank. 
  
 (e) It (i) shall, upon written direction from the Trustee, as entitlement
holder with respect to the Pledge Account, the Pledged Securities and all other Collateral, and without further consent from the Grantor, comply with all instructions, entitlement orders and directions of any kind originated by the Trustee
concerning the Collateral, including without limitation directions to liquidate or otherwise dispose of the Collateral as and to the extent directed by the Trustee and to pay over to the Trustee, or as otherwise directed by the Trustee, all proceeds
and other value 

  

 7 

 
therefrom or otherwise distributed with respect thereto, without any set-off or deduction, and (ii) shall not, except as otherwise directed in writing by the
Trustee, as entitlement holder with respect to the Pledge Account, the Pledged Securities and all other Collateral, comply or agree to comply with any instructions, entitlement orders or directions of any kind that are originated by the Grantor or
any other Person with respect to any of the Collateral. 
  
 (f)
Except for the claims and interests of the Trustee under this Agreement and the rights of the Grantor vis-à-vis the Trustee hereunder, it does not know of any claim to or security interest or other interest in the Collateral. 
  
 (g) It hereby waives its rights to set off any obligations of the Grantor to
it against any or all of the Collateral, and hereby agrees that any and all liens, encumbrances, claims or security interests which it may have against the Collateral, either now or in the future, are and shall be subordinate and junior in right of
payment to the prior payment in full of all Secured Obligations. 
  
 SECTION 7. Representations and Warranties. The Grantor hereby represents and warrants that: 
  
 (a) The execution and delivery by the Grantor of, and the performance by the Grantor of its obligations under, this Agreement will not contravene any
provision of applicable law or the articles of incorporation or by-laws of the Grantor or any material agreement or other material instrument binding upon the Grantor or any judgment, order or decree of any governmental body, agency or court having
jurisdiction over the Grantor, or result in the creation or imposition of any lien on any assets of the Grantor, except for the security interests granted under this Agreement. 
  
 (b) Other than those consents already obtained, no consent of any other Person and no approval, authorization or order of,
action by or qualification with, any governmental authority, regulatory body, agency or other third party is required (i) for the execution, delivery or performance by the Grantor of its obligations under this Agreement or (ii) for the grant by the
Grantor of the security interests created by this Agreement. To the best of Grantor’s knowledge, no consent of any other Person and no approval, authorization or order of, action by or qualification with, any governmental authority, regulatory
body, agency or other third party is required for the exercise by the Trustee of the rights provided for in this Agreement or the remedies in respect of the Collateral pursuant to this Agreement. 
  
 (c) The Grantor is the beneficial owner of the Collateral, free and clear of
any lien or claim of any Person (except for the security interests created by this Agreement and any lien arising under the Indenture in favor of the Trustee). The Grantor has not at any time transferred any of the Collateral to any Person other
than the Trustee or encumbered any of the Collateral with a lien in favor of any other Person. No financing statement or instrument similar in effect covering all or any part of the Grantor’s interest in any of the Collateral is on file in any
public or recording office, other than the financing statements filed pursuant to this Agreement. 
  

 8 

 (d) This Agreement has been duly authorized, executed and delivered by the Grantor and constitutes a
valid and binding agreement of the Grantor, enforceable against the Grantor in accordance with its terms, except as the enforceability hereof may be limited by applicable bankruptcy, insolvency or similar laws affecting creditors’ rights
generally or by equitable principles of general applicability. 
  
 (e) Upon the transfer to the Pledged Securities Intermediary of the Pledged Securities, the crediting thereof to the Pledge Account in accordance with Section 4 above and the execution and delivery of this Agreement by all of the parties
hereto, the grant of a security interest in the Collateral pursuant to this Agreement for the benefit of the Trustee and the Holders of the Securities will create a valid and perfected first priority security interest in such Collateral securing the
payment of the Secured Obligations. 
  
 (f) There are no legal or
governmental proceedings pending or, to the best of the Grantor’s knowledge, threatened to which the Grantor is a party or to which any of the properties of the Grantor is subject that would adversely affect in any material respect the power or
ability of the Grantor to perform its obligations under this Agreement or to consummate the transactions contemplated hereby. 
  
 (g) The pledge of the Collateral pursuant to this Agreement is not prohibited by any law or governmental regulation (including, without limitation,
Regulations U and X of the Board of Governors of the Federal Reserve System) applicable to the Grantor. 
  
 (h) To the best of Grantor’s knowledge, no Default or Event of Default exists. 
  
 (i) The Grantor’s exact legal name is that indicated on the signature page hereof. 
  
 (j) The Grantor is a corporation organized in the Commonwealth of
Massachusetts. 
  
 (k) The Grantor’s place of business or, if
more than one, its chief executive office as well as the Grantor’s mailing address is as is set forth in Section 15.1. 
  
 SECTION 8. Further Assurances. 
  
 (a) The Grantor agrees that from time to time, it will, at its own expense, promptly upon reasonable request by the Trustee, execute and deliver or cause
to be executed and delivered, or use its best efforts to procure, all assignments, instruments and other documents, all in form and substance reasonably satisfactory to the Trustee, deliver any instruments to the Trustee and take any other actions
that may be necessary or, in the reasonable opinion of the Trustee, desirable to perfect, continue the perfection of, or protect the first priority of the Trustee’s security interest in and to the Collateral, to protect the Collateral against
the rights, claims, or interests of third Persons (other than any such rights, claims or interests created by or arising through the Trustee) or to effect the purposes of this Agreement. 
  

 9 

 (b) The Grantor hereby authorizes the Trustee to file any financing or continuation statements with
respect to the Collateral without the signature of the Grantor (to the extent permitted by applicable law); provided, however, that the Grantor shall not be relieved of any of its obligations under Section 8(a) or 8(d) hereof. A photocopy or other
reproduction of this Agreement or any financing statement covering the Collateral or any part thereof shall be sufficient as a financing statement where permitted by law. 
  
 (c) The Grantor will furnish to the Trustee from time to time statements and schedules further identifying and describing
the Collateral and such other reports in connection with the Collateral as the Trustee may reasonably request, all in reasonable detail. 
  
 (d) The Grantor will promptly pay all costs and expenses reasonably incurred in connection with any of the foregoing paragraphs within this Section within
30 days of receipt of an invoice therefor. The Grantor also agrees, whether or not requested by the Trustee, to take all actions that are necessary to perfect and to continue the perfection of, and to protect the first priority of, the
Trustee’s security interest in and to the Collateral, including the filing of all necessary financing and continuation statements, and to protect the Collateral against the rights, claims or interests of third Persons (other than any such
rights, claims or interests created by or arising through the Trustee) and to provide any such financing and continuation statements to the Trustee and the Pledged Securities Intermediary. 
  
 (e) The Grantor hereby irrevocably authorizes the Trustee at any time and
from time to time to file in any Uniform Commercial Code jurisdiction any initial financing statements and amendments thereto that (x) indicate the Collateral as being of an equal or lesser scope or with greater detail, and (y) contain any other
information required by part 5 of Article 9 of the Uniform Commercial Code of the appropriate jurisdiction for the sufficiency or filing office acceptance of any financing statement or amendment; provided that the Trustee shall have no obligation to
perform any of the foregoing actions. 
  
 (f) The Pledged
Securities Intermediary covenants and agrees with the Grantor and the Trustee that for so long as the Pledged Securities Intermediary holds assets in the Pledge Account, the Pledged Securities Intermediary will, as soon as reasonably practicable,
certify in writing the aggregate principal balance of the respective Pledged Securities and the amount of cash balances held in such Pledge Account on a monthly basis, as of the Grantor’s fiscal month end or at such other time as the parties
may mutually agree. The Grantor will provide the Pledged Securities Intermediary with a schedule of its fiscal months as soon as such schedule becomes reasonably available. 
  
 SECTION 9. Covenants. The Grantor covenants and agrees with the Trustee and the Holders of the Securities that from
and after the date of this Agreement until the earlier of (x) payment in full in cash of each of the first six scheduled interest payments due on the Securities (up to and including the interest payment due on April 15, 2007, but excluding
Liquidated Damages, if any) under the terms of the Indenture or (y) payment in cash of Secured Obligations due and owing under the Indenture and the Securities in the event such Secured Obligations 

  

 10 

 
become due and payable prior to the payment in full of the first six scheduled interest payments on the Securities (up to and including the interest payment
due on April 15, 2007, but excluding Liquidated Damages, if any): 
  
 (a) it will not (and will not purport to) sell or otherwise dispose of, or grant any option, right or warrant with respect to, any of the Collateral or its beneficial interest therein, and it will not create or permit to exist any lien or
other adverse interest in or with respect to its beneficial interest in any of the Collateral (except for the security interests granted under this Agreement and any lien arising under the Indenture in favor of the Trustee); 
  
 (b) it will not (i) enter into any agreement or understanding that restricts
or inhibits or purports to restrict or inhibit the Trustee’s rights or remedies hereunder, including without limitation the Trustee’s right to sell or otherwise dispose of the Collateral, or (ii) fail to pay or discharge when due any tax,
assessment or levy of any nature with respect to its beneficial interest in the Collateral not later than five days prior to the date of any proposed sale under any judgment, writ or warrant of attachment with respect to such beneficial interest;
and 
  
 (c) it will not, without providing at least five days
prior written notice to the Trustee, change its name, its place of business or, if more than one, chief executive office, or its mailing address or organizational identification number and will not change its type of organization, jurisdiction of
organization or other legal structure. 
  
 SECTION 10. Power of
Attorney. In addition to all of the powers granted to the Trustee pursuant to the Indenture, the Grantor hereby appoints and constitutes the Trustee as the Grantor’s attorney-in-fact (with full power of substitution), with full authority in
the place and stead of the Grantor and in the name of the Grantor or otherwise, from time to time in the Trustee’s reasonable discretion to take any action and to execute any instrument that the Trustee may deem necessary or advisable to
accomplish the purposes of this Agreement, including, without limitation: 
  
 (a) to ask for, demand, collect, sue for, recover, compromise, receive and give acquittance and receipt for moneys due and to become due under or in respect of any of the Collateral, 
  
 (b) to receive, indorse and collect any drafts or other instruments,
documents and chattel paper, 
  
 (c) to file any claims or take
any action or institute any proceedings that the Trustee may reasonably deem necessary or desirable for the collection of any of the Collateral or otherwise to enforce the rights of the Trustee with respect to any of the Collateral, and 

 
 (d) to pay or discharge any taxes or liens levied or placed upon the
Collateral, the legality or validity thereof and the amounts necessary to discharge the same all as determined by the Trustee in its sole discretion, it being understood that any such payments made by the Trustee 

  

 11 

 
shall become part of the Secured Obligations of the Grantor to the Trustee, and shall be due and payable immediately upon demand; 
  
 provided, however, that the Trustee shall have no obligation to perform any of the foregoing
actions. The Trustee’s authority under this Section 10 shall include, without limitation, the authority to endorse and negotiate any checks or instruments representing proceeds of Collateral in the name of the Grantor, execute and give receipt
for any certificate of ownership or any document constituting Collateral, transfer title to any item of Collateral, authorize the filing of any financing statements (to the extent permitted by applicable law) or any other documents reasonably deemed
necessary or appropriate by the Trustee to preserve, protect or perfect the security interest in the Collateral and to file the same, prepare, file and sign the Grantor’s name on any notice of lien, and to take any other actions arising from or
incident to the powers granted to the Trustee in this Agreement. This power of attorney is coupled with an interest and is irrevocable by the Grantor. 
  
 SECTION 11. No Assumption of Duties; Reasonable Care. The rights and powers conferred on the Trustee hereunder are solely to preserve and protect
the security interest of the Trustee and the Holders of the Securities in and to the Collateral granted hereby and shall not be interpreted to, and shall not, impose any duties on the Trustee in connection therewith other than those expressly
provided herein or in the Indenture or imposed under applicable law. Except as provided by herein, by applicable law or by the Indenture, the Trustee shall be deemed to have exercised reasonable care in the custody and preservation of any Collateral
in its possession if the Collateral is accorded treatment substantially equal to that which the Trustee accords similar property held by itself for its own account, it being understood that the Trustee, in its capacity as such, shall not have any
responsibility for (a) ascertaining or taking action with respect to calls, conversions, exchanges, maturities or other matters relative to any Collateral, whether or not the Trustee has or is deemed to have knowledge of such matters, (b) taking any
necessary steps to preserve rights against any parties with respect to any Collateral or (c) investing or reinvesting any of the Collateral or any loss on any investment. Without limiting any rights of the Trustee hereunder, the rights and
limitations upon the liability of the Trustee set forth in Article 5 of the Indenture are expressly incorporated herein and made a part hereof and shall extend to the role of the Trustee as Pledged Securities Intermediary. 
  
 SECTION 12. Indemnity. The Grantor shall indemnify, hold harmless and
defend the Trustee, the Pledged Securities Intermediary and each of their respective directors, officers, agents and employees, from and against any and all claims, actions, obligations, liabilities and expenses, including defense costs,
investigative fees and costs, and reasonable legal fees and damages arising from their execution of or performance under this Agreement, except to the extent that such claim, action, obligation, liability or expense is directly attributable to the
bad faith, gross negligence or willful misconduct of such indemnified person. This indemnification shall survive the termination of this Agreement. 
  
 SECTION 13. Remedies Upon Event of Default. If prior to April 15, 2007, (i) any Event of Default shall have occurred and be continuing and (ii) the
Trustee, by notice to the 

  

 12 

 
Grantor, or the Holders of at least 25% in aggregate principal amount of the Securities at the time outstanding by written notice to the Grantor and the
Trustee, may declare the Notes due and payable at their principal amount together with any accrued and unpaid interest; provided if an Event of Default specified in clauses (g) or (h) of Section 5.01 of the Indenture occurs and is continuing, then
the principal and any accrued and unpaid interest on all the Securities shall become and be immediately due and payable without any declaration or other act on the part of the Trustee or any Holders, then: 
  
 (a) The Trustee may exercise, in addition to all other rights given by law or
by this Agreement or the Indenture, all of the rights and remedies with respect to the Collateral of a secured party under the Uniform Commercial Code as in effect from time to time in any relevant jurisdiction and also may, without notice except as
specified below, (i) sell, redeem or liquidate any of the Collateral, (ii) transfer any or all of the Collateral to any account designated by the Trustee, including an account or accounts established in the Trustee’s name, (iii) register title
to any Collateral in any name specified by the Trustee, including the name of the Trustee or any of its nominees or agents, without reference to any interest of the Grantor, or (iv), sell the Collateral or any part thereof in one or more parcels at
any broker’s board or at public or private sale, in one or more sales or lots, at any of the Trustee’s offices or elsewhere, for cash, on credit or for future delivery, and upon such other terms as the Trustee may deem commercially
reasonable. The Grantor agrees that the Collateral is of a type customarily sold on recognized markets and, accordingly, that no notice to any Person is required before any sale of any of the Collateral pursuant to the terms of this Agreement;
provided, however that, without prejudice to the foregoing, to the extent notice of any such sale shall be required by law, the Grantor agrees that at least ten days’ notice to the Grantor of the time and place of any public sale or the time
after which any private sale is to be made shall constitute reasonable notification. The Trustee shall not be obligated to make any sale of Collateral regardless of notice of sale having been given. The Trustee may adjourn any public or private sale
from time to time by announcement at the time and place fixed therefor, and such sale may, without further notice, be made at the time and place to which it was so adjourned. The purchaser of any or all Collateral so sold shall thereafter hold the
same absolutely free from any claim, encumbrance or right of any kind whatsoever created by or through the Grantor. Any sale of the Collateral conducted in conformity with reasonable commercial practices of banks, insurance companies, commercial
finance companies, or other financial institutions disposing of property similar to the Collateral shall be deemed to be commercially reasonable. The Trustee or any Holder of Securities may, in its own name or in the name of a designee or nominee,
buy any of the Collateral at any public sale and, if permitted by applicable law, at any private sale. All expenses (including court costs and reasonable attorneys’ fees, expenses and disbursements) of, or incident to, the enforcement of any of
the provisions hereof shall be recoverable from the proceeds of the sale or other disposition of the Collateral. If there are insufficient Pledged Securities together with proceeds of Pledged Securities and other Collateral in the Pledge Account to
make any required payment on the Secured Obligations, the Grantor shall be liable to the Trustee for any deficiency. 
  
 (b) All cash proceeds received by or on behalf of the Trustee in respect of any sale of, collection from, or other realization upon all or any part of the
Collateral may, following the 

  

 13 

 
payment of the reasonable fees and expenses of the Trustee and the Pledged Securities Intermediary, be held by the Trustee (or by the Pledged Securities
Intermediary on its behalf) as collateral for, and/or then or at any time thereafter applied (after payment of any amounts payable to the Trustee pursuant to Section 14) in whole or in part by the Trustee as follows: 
  
 FIRST: To the payment of the amount equal to all accrued and
unpaid interest on the Securities; and 
  
 SECOND: To the repayment of a portion of the principal of the Securities and accrued and unpaid Liquidated Damages, if any. 
  
 (c) The Trustee may, without notice to the Grantor except as required by law and at any time or from time to time, charge, set-off and otherwise apply all
or any part of the Secured Obligations against the Pledge Account or any part thereof. 
  
 (d) The Grantor further agrees to use its best efforts to do or cause to be done all such other acts as may be necessary to make such sale or sales of all or any portion of the Collateral pursuant to this Section 13
valid and binding and in compliance with any and all other applicable requirements of law. The Grantor further agrees that a breach of any of the covenants contained in this Section 13 will cause irreparable injury to the Trustee and the Holders of
the Securities, that the Trustee and the Holders of the Securities have no adequate remedy at law in respect of such breach and, as a consequence, that each and every covenant contained in this Section 13 shall be specifically enforceable against
the Grantor and, to the fullest extent permitted by law, the Grantor hereby waives and agrees not to assert any defenses against an action for specific performance of such covenants except for a defense that no Event of Default has occurred and is
continuing. 
  
 (e) Notwithstanding the foregoing, the Trustee and
the Holders of the Securities shall not have the benefit of the remedies set forth in this Section 13 if an Event of Default has occurred but is cured prior to the acceleration of the Securities by the Trustee or the Holders of the Securities.

  
 SECTION 14. Expenses. The Grantor will promptly upon
demand pay to the Trustee and the Pledged Securities Intermediary the amount of any and all reasonable expenses, including, without limitation, the reasonable fees, expenses and disbursements of counsel, experts and agents retained by the Trustee or
the Pledged Securities Intermediary, as the case may be, that the Trustee or the Pledged Securities Intermediary, as the case may be, may incur in connection with (a) the review, negotiation and administration of this Agreement, (b) the custody or
preservation of, or the sale of, collection from, or other realization upon, any of the Collateral, (c) the exercise or enforcement of any of the rights of the Trustee and the Holders of the Securities hereunder or (d) the failure by the Grantor to
perform or observe any of the provisions hereof. 
  

 14 

 SECTION 15. Miscellaneous Provisions. 
  
 Section 15.1. Notices. Any notice or other communication given
hereunder shall be sufficiently given if in writing and delivered in person or mailed by first class mail, commercial courier service or telecopier communication, addressed as follows: 
  
 If to the Grantor: 
  
 Oscient Pharmaceuticals Corporation 
 100
Deaver Street 
 Waltham Massachusetts 02453 
 Attention: Chief Financial Officer 
 Fax: (781) 893-9535 
  
 If to the Trustee or Pledged Securities Intermediary: 
  
 U.S. Bank National Association 
  
 One Federal Street, 3rd Floor 
 Boston, Massachusetts 02110 
 Attention: Alison Nadeau 
 Fax: (617) 603-6683

 Phone: (617) 603-6553 
  
 All such notices and other communications shall, when mailed, delivered or telecopied, respectively, be effective when deposited in the mails, delivered
or telecopied, respectively, addressed as aforesaid. 
  
 Section
15.2. No Adverse Interpretation of Other Agreements. This Agreement may not be used to interpret another pledge, security or debt agreement of the Grantor or any subsidiary thereof. No such pledge, security or debt agreement (other than the
Indenture) may be used to interpret this Agreement. 
  
 Section
15.3. Severability. The provisions of this Agreement are severable, and if any clause or provision shall be held invalid, illegal or unenforceable in whole or in part in any jurisdiction, then, to the fullest extent permitted by law, such
invalidity or unenforceability shall affect in that jurisdiction only such clause or provision, or part thereof, and shall not in any manner affect such clause or provision in any other jurisdiction or any other clause or provision of this Agreement
in any jurisdiction. 
  
 Section 15.4. Headings. The
headings in this Agreement have been inserted for convenience of reference only, are not to be considered a part hereof and shall in no way modify or restrict any of the terms or provisions hereof. 
  

 15 

 Section 15.5. Counterpart Originals. This Agreement may be signed in two or more counterparts,
each of which shall be deemed an original, but all of which shall together constitute one and the same agreement. 
  
 Section 15.6. Benefits of Agreement. Nothing in this Agreement, express or implied, shall give to any Person, other than the parties hereto and
their successors hereunder, and the Holders of the Securities, any benefit or any legal or equitable right, remedy or claim under this Agreement. 
  
 Section 15.7. Amendments, Waivers and Consents. Any amendment or waiver of any provision of this Agreement and any consent to any departure by the
Grantor from any provision of this Agreement shall be effective only if made or duly given in compliance with all of the terms and provisions of the Indenture, and then such waiver or consent shall be effective only in the specific instance and for
the specific purpose for which given, provided that an amendment or supplement to this Agreement for the purpose contemplated by Section 16 may be entered into by the Grantor, the Trustee and the Pledged Securities Intermediary without the consent
of any Holder, so long as such amendment or supplement is reasonably satisfactory in form and substance to the Grantor, the Trustee and the Pledged Securities Intermediary. Neither the Trustee nor any Holder of Securities shall be deemed, by any
act, delay, indulgence, omission or otherwise, to have waived any right or remedy hereunder or to have acquiesced in any Event of Default or in any breach of any of the terms and conditions hereof. Failure of the Trustee or any Holder of Securities
to exercise, or delay in exercising, any right, power or privilege hereunder shall not preclude any other or further exercise thereof or the exercise of any other right, power or privilege. A waiver by the Trustee or any Holder of Securities of any
right or remedy hereunder on any one occasion shall not be construed as a bar to any right or remedy that the Trustee or such Holder would otherwise have on any future occasion. The rights and remedies herein provided are cumulative, may be
exercised singly or concurrently and are not exclusive of any rights or remedies provided by law. 
  
 Section 15.8. Interpretation of Agreement. To the fullest extent permitted by applicable law, acceptance of or acquiescence in a course of
performance rendered under this Agreement shall not be relevant to determine the meaning of this Agreement even though the accepting or acquiescing party had knowledge of the nature of the performance and opportunity for objection. 
  
 Section 15.9. Continuing Security Interest; Termination. 

 
 (a) This Agreement shall create a continuing security interest in and to
the Collateral and shall, unless otherwise provided in this Agreement, remain in full force and effect until the payment in cash of the Secured Obligations. This Agreement shall be binding upon the Grantor, its transferees, successors and assigns,
and shall inure, together with the rights and remedies of the Trustee hereunder, to the benefit of the Trustee, the Holders of the Securities, the Pledged Securities Intermediary and their respective successors, transferees and assigns. 

 
 (b) This Agreement (other than Grantor’s obligations under Sections
12 and 14) shall terminate upon the earlier of (i) the payment in cash of the Secured Obligations and (ii) the 

  

 16 

 
payment in full in cash of the first six scheduled interest payments on all of the Securities. At such time, the Trustee shall, pursuant to an Issuer Order,
direct the Pledged Securities Intermediary to promptly transfer to the Grantor all of the Collateral hereunder that has not been sold, disposed of, retained or applied by or on behalf of the Trustee in accordance with the terms of this Agreement and
the Indenture and take all other actions that are necessary to release the security interest created by this Agreement in and to the Collateral, including the execution and delivery of all termination statements necessary to terminate any financing
or continuation statements filed with respect to the Collateral. Such transfer shall be without warranty by or recourse to the Trustee in its capacity as such, except as to the absence of any liens on the Collateral created by or arising through the
Trustee, and shall be at the expense of the Grantor. 
  
 Section
15.10. Survival of Representations and Covenants. All representations, warranties and covenants of the Grantor contained herein shall survive the execution and delivery of this Agreement and the termination of this Agreement. 
  
 Section 15.11. Waivers. The Grantor, to the fullest extent permitted
by applicable law, waives presentment and demand for payment of any of the Obligations, protest and notice of dishonor or default with respect to any of the Obligations, and all other notices to which the Grantor might otherwise be entitled, except
as otherwise expressly provided herein or in the Indenture. 
  
 Section 15.12. Authority of the Trustee. 
  
 (a)
The Trustee shall have and be entitled to exercise all powers hereunder that are specifically granted to it by the terms hereof, together with such powers as are reasonably incident thereto. The Trustee may perform any of its duties hereunder or in
connection with the Collateral by or through agents or employees and shall be entitled to retain counsel and to act in reliance upon the advice of counsel concerning all such matters. Except as otherwise expressly provided in this Agreement or the
Indenture, neither the Trustee nor any director, officer, employee, attorney or agent of the Trustee shall be liable to the Grantor for any action taken or omitted to be taken by the Trustee, in its capacity as Trustee, hereunder, except for its own
bad faith, gross negligence or willful misconduct, and the Trustee shall not be responsible for the validity, effectiveness or sufficiency hereof or of any document or security furnished pursuant hereto. The Trustee and its directors, officers,
employees, attorneys and agents shall be entitled to rely on any communication, instrument or document reasonably believed by it or them to be genuine and correct and to have been signed or sent by the proper person or persons. 
  
 (b) The Grantor acknowledges that the rights and responsibilities of the
Trustee under this Agreement with respect to any action taken by the Trustee or the exercise or non-exercise by the Trustee of any option, right, request, judgment or other right or remedy provided for herein or resulting or arising out of this
Agreement shall, as between the Trustee and the Holders of the Securities, be governed by the Indenture and by such other agreements with respect thereto as may exist from time to time among them, but, as between the Trustee and the Grantor, the
Trustee shall be conclusively presumed to be acting as agent for the Holders of the Securities 

  

 17 

 
with full and valid authority so to act or refrain from acting, and the Grantor shall not be obligated or entitled to make any inquiry respecting such
authority. 
  
 Section 15.13. Final Expression. This
Agreement, together with the Indenture and any other agreement executed in connection herewith, is intended by the parties as a final expression of this Agreement and is intended as a complete and exclusive statement of the terms and conditions
thereof. 
  
 Section 15.14. Rights of Holders of the
Securities. No Holder of Securities shall have any independent rights hereunder other than those rights granted to individual Holders of the Securities pursuant to the Indenture; provided that nothing in this subsection shall limit any rights
granted to the Trustee under the Securities or the Indenture. 
  
 Section 15.15. Governing Law; Submission to Jurisdiction; Waiver of Jury Trial; Waiver of Damages. 
  
 (a) THIS AGREEMENT SHALL BE GOVERNED BY AND INTERPRETED UNDER THE LAWS OF THE STATE OF NEW YORK. 
  
 (b) ANYTHING CONTAINED IN THIS AGREEMENT OR IN ANY OTHER AGREEMENT BETWEEN
THE TRUSTEE AND THE PLEDGED SECURITIES INTERMEDIARY TO THE CONTRARY NOTWITHSTANDING, THE “PLEDGED SECURITIES INTERMEDIARY’S JURISDICTION” WITH RESPECT TO THE PLEDGED SECURITIES FOR PURPOSES OF SECTIONS 8-110(e), 9-305(a)(3) AND
9-304(b)(1) OF THE UCC SHALL BE THE STATE OF NEW YORK. 
  
 (c) FOR
ANY SUIT, ACTION OR PROCEEDING WITH RESPECT TO THIS AGREEMENT, THE GRANTOR HEREBY AGREES TO SUBMIT TO THE JURISDICTION OF ANY FEDERAL OR STATE COURT LOCATED IN THE CITY OF NEW YORK. 
  
 (d) THE GRANTOR AGREES THAT THE TRUSTEE SHALL, IN ITS CAPACITY AS TRUSTEE OR IN THE NAME AND ON BEHALF OF ANY HOLDER OF
SECURITIES, HAVE THE RIGHT, TO THE FULLEST EXTENT PERMITTED BY APPLICABLE LAW (AND TO THE EXTENT THE TRUSTEE HAS RECEIVED INDEMNITY DEEMED SATISFACTORY TO IT AND HAS AGREED TO DO SO), TO PROCEED AGAINST THE GRANTOR OR THE COLLATERAL IN A COURT IN
ANY LOCATION REASONABLY SELECTED IN GOOD FAITH (AND HAVING PERSONAL OR IN REM JURISDICTION OVER THE GRANTOR OR THE COLLATERAL, AS THE CASE MAY BE) TO ENABLE THE TRUSTEE TO REALIZE ON SUCH COLLATERAL, OR TO ENFORCE A JUDGMENT OR OTHER COURT ORDER
ENTERED IN FAVOR OF THE TRUSTEE. THE GRANTOR AGREES, TO THE FULLEST EXTENT PERMITTED BY APPLICABLE LAW, THAT IT WILL NOT ASSERT ANY COUNTERCLAIMS, SETOFFS OR CROSSCLAIMS IN ANY PROCEEDING BROUGHT BY THE TRUSTEE TO REALIZE ON SUCH PROPERTY OR TO
ENFORCE A JUDGMENT OR OTHER COURT ORDER IN FAVOR OF THE TRUSTEE, EXCEPT FOR SUCH COUNTERCLAIMS, SETOFFS OR CROSSCLAIMS WHICH, IF NOT 

  

 18 

 
ASSERTED IN ANY SUCH PROCEEDING, COULD NOT OTHERWISE BE BROUGHT OR ASSERTED. THE GRANTOR WAIVES, TO THE FULLEST EXTENT PERMITTED BY APPLICABLE LAW, ANY
OBJECTION THAT IT MAY HAVE TO THE LOCATION OF THE COURT IN THE CITY OF NEW YORK IN THE BOROUGH OF MANHATTAN ONCE THE TRUSTEE HAS COMMENCED A PROCEEDING DESCRIBED IN THIS PARAGRAPH INCLUDING, WITHOUT LIMITATION, ANY OBJECTION TO THE LAYING OF VENUE
OR BASED ON THE GROUNDS OF FORUM NON CONVENIENS. 
  
 (e) THE
GRANTOR AGREES THAT NONE OF ANY HOLDER OF SECURITIES, (EXCEPT AS OTHERWISE PROVIDED IN THIS AGREEMENT OR THE INDENTURE) THE TRUSTEE IN ITS CAPACITY AS TRUSTEE, OR U.S. BANK NATIONAL ASSOCIATION IN ITS CAPACITY AS PLEDGED SECURITIES INTERMEDIARY
SHALL HAVE ANY LIABILITY TO THE GRANTOR (WHETHER ARISING IN TORT, CONTRACT OR OTHERWISE) FOR LOSSES SUFFERED BY THE GRANTOR IN CONNECTION WITH, ARISING OUT OF, OR IN ANY WAY RELATED TO, THE TRANSACTIONS CONTEMPLATED AND THE RELATIONSHIP ESTABLISHED
BY THIS AGREEMENT, OR ANY ACT, OMISSION OR EVENT OCCURRING IN CONNECTION THEREWITH, UNLESS SUCH LOSSES WERE THE RESULT OF ACTS OR OMISSIONS ON THE PART OF THE TRUSTEE OR SUCH HOLDERS OF SECURITIES, AS THE CASE MAY BE, CONSTITUTING BAD FAITH, GROSS
NEGLIGENCE OR WILLFUL MISCONDUCT. 
  
 (f) TO THE FULLEST EXTENT
PERMITTED BY APPLICABLE LAW, THE GRANTOR WAIVES THE POSTING OF ANY BOND OTHERWISE REQUIRED OF THE TRUSTEE OR ANY HOLDER OF SECURITIES IN CONNECTION WITH ANY JUDICIAL PROCESS OR PROCEEDING TO ENFORCE ANY JUDGMENT OR OTHER COURT ORDER PERTAINING TO
THIS AGREEMENT OR ANY RELATED AGREEMENT OR DOCUMENT ENTERED IN FAVOR OF THE TRUSTEE OR ANY HOLDER OF SECURITIES, OR TO ENFORCE BY SPECIFIC PERFORMANCE, TEMPORARY RESTRAINING ORDER OR PRELIMINARY OR PERMANENT INJUNCTION, THIS AGREEMENT OR ANY RELATED
AGREEMENT OR DOCUMENT BETWEEN THE GRANTOR ON THE ONE HAND AND THE TRUSTEE AND/OR THE HOLDERS OF THE SECURITIES ON THE OTHER HAND. 
  
 SECTION 16. Provisions Relating to Additional Securities. The Grantor and the Trustee, on behalf of the Holders of the Securities originally issued
on the date hereof (the “Firm Securities”) and on behalf of the Holders of any “Additional Securities” (as defined in the Purchase Agreement dated May 4, 2004 among the Grantor and the Initial Purchasers named
therein and relating to the Securities), hereby acknowledge that the Grantor may issue Additional Securities from time to time after the date hereof and that, pursuant to the terms of the Indenture, the Firm Securities and any Additional Securities
will be treated as part of a single class for all purposes under the Indenture. Accordingly, anything contained herein to the contrary notwithstanding, (a) upon the issuance of any Additional Securities (i) for all purposes under this Agreement the
term “Securities” shall thereafter include such Additional Securities; provided 

  

 19 

 
that any references herein to the first six scheduled interest payments due on the Securities shall mean, with respect to such Additional Securities, only
such number, if any, of the first six scheduled interest payments on the Securities as shall then remain at the time such Additional Securities are originally issued (such number, if any, of the first six scheduled interest payments on the
Securities that shall remain at such time being the “Covered Interest Payments” in respect of such Additional Securities), (ii) in the event that any Additional Securities are issued prior to such time as the first six scheduled
interest payments on the Securities shall have been paid in full, the Grantor shall purchase or cause to be purchased, for the account of the Pledged Securities Intermediary for credit to the Pledge Account, additional security entitlements with
respect to U. S. Government Securities (such security entitlements being, collectively, the “Additional Pledged Securities”) in an amount that will be sufficient, upon receipt of the scheduled interest and principal payments in
respect thereof, to provide for the payment of all Covered Interest Payments in respect of such Additional Securities, and (iii) for all purposes under this Agreement and the Indenture (including without limitation Section 4(b)) the term
“Pledged Securities” shall thereafter include any such Additional Pledged Securities, and (b) as provided in Section 15.7, in connection with the issuance of any Additional Securities, the parties hereto shall be permitted to enter
into such amendments or supplements to this Agreement as may be necessary or advisable in order to give effect to the provisions of this Section 16 without the consent of the Holders of the Firm Securities or the Holders of any Additional Securities
that are outstanding at the time of such issuance. For the avoidance of doubt and without limiting the generality of the foregoing, the Grantor and the Trustee, on behalf of the Holders of the Securities, hereby acknowledge and agree that the
Holders of the Firm Securities and the Holders of any Additional Securities shall be entitled to share ratably in the benefits of this Agreement. In the event that the Grantor shall issue Additional Securities on more than one occasion, then the
provisions of this Section 16 shall apply to such successive issuances of Additional Securities, mutatis mutandis. 
  

 20 

 IN WITNESS WHEREOF, the Grantor, the Trustee and the Pledged Securities Intermediary have each caused
this Agreement to be duly executed and delivered as of the date first above written. 
  

			
	Grantor:
	
	OSCIENT PHARMACEUTICALS CORPORATION
		
	By:	 	/s/    STEPHEN COHEN
	 Name:
	 	Stephen Cohen
	 Title:
	 	Senior Vice President and CFO
	
	Trustee:
	
	 U.S. BANK NATIONAL ASSOCIATION

		
	By:	 	/s/    GEORGE H. DAVISON
	 Name:
	 	George H. Davison
	 Title:
	 	Officer
	
	Pledged Securities Intermediary:
	
	 U.S. BANK NATIONAL ASSOCIATION

		
	By:	 	/s/    GEORGE H. DAVISON
	 Name:
	 	George H. Davison
	 Title:
	 	Officer

  

 21 

 SCHEDULE I 
  
 PLEDGED SECURITIES 
  

							
	 SECURITY

	  	 CUSIP NO.

	  	 MATURITY

	  	 PRINCIPAL AMOUNT

	 United States Treasury
	  	912833CL2	  	8/15/04	  	1,878,253.80
	 United States Treasury
	  	912883CM0	  	2/15/04	  	2,161,612.72
	 United States Treasury
	  	912833CN8	  	8/15/05	  	2,135,422.36
	 United States Treasury
	  	912833CP3	  	2/15/06	  	2,097,351.16
	 United States Treasury
	  	912833CQ1	  	8/15/06	  	2,059,892.60
	 United States Treasury
	  	912833CR9	  	2/15/07	  	2.011,143.96
	 TOTAL
	  	 	  	 	  	$12,343,676.60

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