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                                                                  EXHIBIT 10.23

                                NEUROMETRIX, INC.

                     CONFIDENTIALITY & NON-COMPETE AGREEMENT

In consideration of and as a condition to my employment, or if now employed in
consideration of and as a condition to my continued employment, by NeuroMetrix,
Inc. (the "Company"), the granting of shares of common, no par value stock of
the Company, and the compensation now and hereafter paid to me by the Company
and other good and valuable consideration, the sufficiency of which I hereby
acknowledge, I hereby execute this Confidentiality & Non-Compete Agreement (the
"Agreement") and agree to the following:

1.   CONFIDENTIAL INFORMATION.

     a)     COMPANY INFORMATION. I agree at all times during the term of my
            employment and thereafter to hold in strictest confidence, and not
            to use, except for the benefit of the Company, or to disclose to any
            person, firm or corporation without the prior written authorization
            of a duly authorized officer of the Company, any Confidential
            Information of the Company. I understand that "Confidential
            Information" means any Company proprietary information, technical
            data, trade secrets or know-how, including, but not limited to,
            research and development information, product plans, products,
            services, customer lists and customers, Work Product (as defined
            below), suppliers, software developments, inventions, processes,
            formulas, technology, designs, drawings, engineering information,
            hardware configuration information, marketing information, costs,
            pricing, finances or other business information disclosed to me by
            the Company either directly or indirectly in writing, orally or by
            drawings or inspection of parts or equipment either before or after
            the commencement of my employment. I further agree that all
            Confidential Information shall at all times remain the property of
            the Company. I understand that Confidential Information does not
            include any of the foregoing items which has become publicly known
            or made generally available through no wrongful act of mine.

     b)     THIRD-PARTY INFORMATION. I recognize that the Company has received
            and in the future will receive from third parties their confidential
            or proprietary information subject to a duty on the Company's part
            to maintain the confidentiality of such information and to use it
            only for certain limited purposes. I agree to hold all such
            confidential or proprietary information in the strictest confidence
            and not to disclose it to any person, firm or corporation or to use
            it except as necessary in carrying out my work for the Company
            consistent with the Company's agreement with such third party.

2.   WORK PRODUCT.

     a)     ASSIGNMENT OF WORK PRODUCT. I agree that I will promptly make full
            written disclosure to the Company and will hold in trust for the
            sole right and benefit of the Company, and I hereby assign to the
            Company, or its designee, all my right, title and interest in and to
            any and all inventions, original works of authorship, developments,
            concepts,

                                   Page 1 of 5
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            improvements or trade secrets, of whatever nature and whether or not
            patentable or registrable under copyright or similar laws, which I
            may solely or jointly with others conceive or develop or reduce to
            practice, or cause to be conceived or developed or reduced to
            practice, during the period of time I am in the employ of the
            Company (collectively referred to as "Work Product"); and I further
            agree that the foregoing shall also apply to Work Product which
            relates the business of the Company or to the Company's anticipated
            business as of the end of my employment and which is conceived,
            developed, or reduced to practice during a period of one (1) year
            after the end of my employment. Without limiting the foregoing, I
            further acknowledge that all original works of authorship which are
            made by me (solely or jointly with others) within the scope of my
            employment and which are protectable by copyright are "works made
            for hire", as that term is defined in the United States Copyright
            Act.

     b)     MAINTENANCE OF RECORDS. I agree to keep and maintain adequate and
            current written records of all Work Product made by me (solely or
            jointly with others) during the term of my employment by the
            Company. The records will be in form of notes, sketches, drawings,
            and any other format that may be specified by the Company. The
            records will be available to and remain the sole property of the
            Company at all times.

     c)     PATENT AND COPYRIGHT REGISTRATIONS. I agree to assist the Company,
            or its designee, at the Company's expense, in every proper way to
            secure the Company's rights in the Work Product and any copyrights,
            patents, mask work rights or other intellectual property rights
            relating thereto in any and all countries, including the disclosure
            to the Company of all pertinent information and data with respect
            thereto and the execution of all applications, specifications,
            oaths, assignments and all other instruments which the Company shall
            deem necessary in order to apply for and obtain such rights and in
            order to assign and convey to the Company, its successors, assigns
            and nominees to sole and exclusive rights, title and interest in and
            to such Work Product, and any copyright, patents, mask work rights
            or other intellectual property rights relating thereto. This
            provision shall survive the termination of my employment by the
            Company, whether with or without cause.

3.   RETURNING COMPANY PROPERTY. I agree that, at any time upon request of the
     Company, and in any event at the time of the termination of my employment
     by Company, I will deliver to the Company (and will not keep in my
     possession or deliver to anyone else) any and all devices, records, data,
     notes, reports, proposals, lists, correspondence, specifications, drawings,
     blueprints, sketches, materials, equipment, other documents or property, or
     reproductions of any of the aforementioned items, containing Confidential
     Information or otherwise belonging to the Company, its successors or
     assigns, whether prepared by me or supplied to me by the Company.

4.   CONFLICTS

     a)     CONFLICTING EMPLOYMENT. I agree that, during the term of my
            employment by the Company, I will not engage in any other
            employment, occupation, consulting or other business activity
            related to the business in which the Company is now involved or

                                   Page 2 of 5
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            becomes involved during the term of my employment, nor will I engage
            in any other activities that conflict with my obligations to
            Company.

     B)     NO RESTRICTIONS. I am subject to no contractual or other restriction
            or obligation which will in any way limit my activities on behalf of
            the Company. I hereby represent and warrant to the Company that I do
            not claim rights in, or otherwise exclude from this Agreement, any
            Work Product (as defined above) or pervious work completed by me
            except the following (NOTE: IF NONE, PLEASE WRITE "NONE "; OR
            ADDITIONAL INFORMATION IS PROVIDED ON A SEPARATE SHEET, PLEASE SO
            INDICATE): _________________________________________________________
            ___________________________________________________________________.

5.   COVENANT AGAINST COMPETITION.

     a)     For the purposes of this Section:

            i)    "Competing Product" means any product, process, or service of
                  any person or organization other than the Company, in
                  existence or under development, (A) which is identical to,
                  substantially the same as, or an adequate substitute for any
                  product, process, or service of the Company, in existence or
                  under development, on which I work during the time of my
                  employment by the Company or about which I acquire
                  Confidential Information, and (B) which is (or could
                  reasonably be anticipated to be) marketed or distributed in
                  such a manner and in such a geographic area as to actually
                  compete with such product, process or services of the Company.

            ii)   "Competing Organization" means any person or organization,
                  including myself, engaged in, or about to become engaged in,
                  research on or the acquisition, development, production,
                  distribution, marketing, or providing of a Competing Product.

     b)     As a material inducement to the Company to employ me, and in order
            to protect the Company's Confidential Information and good will, I
            agree to the following stipulations:

            i)    For a period of twelve (12) months after termination of my
                  employment by the Company, whether with or without cause, I
                  will not directly or indirectly solicit or divert or accept
                  business relating in any manner to Competing Products or to
                  products, processes or services of the Company from any of the
                  customers or accounts of the Company with which I had any
                  contact as a result of my employment.

            ii)   For a period of twelve (12) months after termination of my
                  employment by the Company or its affiliates for any reason,
                  whether with or without cause, I will not render services,
                  directly or indirectly, as an employee, consultant or
                  otherwise, to any Competing Organization in connection with
                  research on or the acquisition,

                                   Page 3 of 5
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                  development, production, distribution, marketing, or
                  production of any Competing Product.

            iii)  For a period of twelve (12) months after termination of my
                  employment by the Company, whether with or without cause, I
                  will not directly or indirectly solicit or take away, or
                  attempt to solicit or take away, employees of the Company,
                  either for my own business or for any other person or entity.

6.   ENFORCEABILITY AND SEVERABILITY. In the event that any provision of this
     Agreement shall be determined to be unenforceable by any court of competent
     jurisdiction by reason of its extending for too great a period of time or
     over too large a geographic area or over too great a range of activities,
     it shall be interpreted to extend only over the maximum period of time,
     geographic area or range of activities as to which it may be enforceable.

     If any provision of this Agreement shall be determined to be invalid,
     illegal or otherwise unenforceable by any court of competent jurisdiction,
     the validity, legality and enforceability of the other provisions of this
     Agreement shall not be affected thereby. Any invalid, illegal or
     unenforceable provision of this Agreement shall be severable, and after any
     such severance, all other provisions hereof shall remain in full force and
     effect.

7.   BREACH.

     a)     EQUITABLE REMEDIES. I hereby expressly acknowledge that any breach
            or threatened breach of any of the terms and/or conditions set forth
            in this Agreement will result in substantial, continuing and
            irreparable injury to the Company. Therefore, I hereby agree that,
            in addition to any other remedy that may be available to the
            Company, the Company shall be entitled to injunctive or other
            equitable relief by a court of appropriate jurisdiction in the event
            of breach or threatened breach of the terms of this Agreement.

     b)     TOLLING. If any provisions of this Agreement are violated, then the
            time limitations set forth in this Agreement shall be extended for a
            period of time equal to the period of time during which such breach
            occurs, and, in the event the Company is required to seek relief
            from such breach before any court, board or other tribunal, then the
            time limitation shall be extended for a period of time equal to the
            pendency of such proceedings, including all appeals.

8.   GENERAL PROVISIONS

     a)     ENTIRE AGREEMENT. This Agreement supersedes all previous agreements,
            written or oral, between the Company and me relating to the subject
            matter of this Agreement, sets forth the entire agreement and
            understanding between the Company and me relating to the subject
            matter herein and merges all prior discussions between us with
            respect hereto. No modification of or amendment to this Agreement,
            nor any waiver of any rights under this Agreement, will be effective
            unless in writing signed by the party to be

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            charged. Any subsequent change or changes in my duties, job title or
            compensation will not affect the validity or scope of this
            Agreement.

     b)     SUCCESSORS AND ASSIGNS. This Agreement shall inure to the benefit of
            the Company and its legal representatives, successors and assigns,
            and shall be binding upon me and my heirs, legal representatives,
            successors and assigns.

     c)     GOVERNING LAW. This Agreement will be governed by the laws of the
            Commonwealth of Massachusetts, without regard to conflicts of law
            principles.

     d)     HEADINGS. The headings in this Stockholders Agreement are for
            convenience of reference only, and they shall not limit or otherwise
            affect the interpretation of any term or provision hereof.

I ACKNOWLEDGE THAT BEFORE PLACING MY SIGNATURE HEREUNDER, I HAVE READ ALL OF THE
PROVISIONS OF THIS AGREEMENT AND HAVE RECEIVED A COPY HEREOF TODAY. I FURTHER
ACKNOWLEDGE THAT ALTHOUGH THIS AGREEMENT HAS BEEN SIGNED AFTER THE COMMENCEMENT
OF MY EMPLOYMENT, IT APPLIES TO ANY AND ALL INFORMATION RECEIVED BY ME DURING MY
EMPLOYMENT.

Executed as a document under seal effective as of November 1, 2000.

                                  Signed:

                                  /s/ Nicholas J. Alessi
                                  ---------------------------------------------
                                  [Employee's Signature] Nicholas J. Alessi

                                  42 Pleasant Street
                                  ---------------------------------------------
                                  [Address]

                                  Hyde Park, MA 02136
                                  ---------------------------------------------
                                  [City, State and Zip Code]

For NeuroMetrix, Inc.

/s/ Shai N. Gozani, M.D., Ph.D.
-------------------------------------------
Authorized Signature

                                   Page 5 of 5<Page>

                                                                  EXHIBIT 10.24

                                NEUROMETRIX, INC.

                     CONFIDENTIALITY & NON-COMPETE AGREEMENT

In consideration of and as a condition to my continued employment on an
at-will basis, by NeuroMetrix, Inc. (the "Company"), the granting of shares
of common, no par value stock of the Company, and the compensation now and
hereafter paid to me by the Company and other good and valuable
consideration, the sufficiency of which I hereby acknowledge, I hereby
execute this Confidentiality & Non-Compete Agreement (the "Agreement") and
agree to the following:

1.   CONFIDENTIAL INFORMATION.

     a)     COMPANY INFORMATION. I agree at all times during the term of my
            employment and thereafter to hold in strictest confidence, and not
            to use, except for the benefit of the Company, or to disclose to any
            person, firm or corporation without the prior written authorization
            of a duly authorized officer of the Company, any Confidential
            Information of the Company. I understand that "Confidential
            Information" means any Company proprietary information, technical
            data, trade secrets or know-how, including, but not limited to,
            research and development information, product plans, products,
            services, customer lists and customers, Work Product (as defined
            below), suppliers, software developments, inventions, processes,
            formulas, technology, designs, drawings, engineering information,
            hardware configuration information, marketing information, costs,
            pricing, finances or other business information disclosed to me by
            the Company either directly or indirectly in writing, orally or by
            drawings or inspection of parts or equipment either before or after
            the commencement of my employment. I further agree that all
            Confidential Information shall at all times remain the property of
            the Company. I understand that Confidential Information does not
            include any of the foregoing items which has become publicly known
            or made generally available through no wrongful act of mine.

     b)     THIRD-PARTY INFORMATION. I recognize that the Company has received
            and in the future will receive from third parties their confidential
            or proprietary information subject to a duty on the Company's part
            to maintain the confidentiality of such information and to use it
            only for certain limited purposes. I agree to hold all such
            confidential or proprietary information in the strictest confidence
            and not to disclose it to any person, firm or corporation or to use
            it except as necessary in carrying out my work for the Company
            consistent with the Company's agreement with such third party.

2.   WORK PRODUCT.

     a)     ASSIGNMENT OF WORK PRODUCT. I agree that I will promptly make full
            written disclosure to the Company and will hold in trust for the
            sole right and benefit of the Company, and I hereby assign to the
            Company, or its designee, all my right, title and interest in and to
            any and all inventions, original works of authorship, developments,
            concepts,

                                   Page 1 of 5
<Page>

            improvements or trade secrets, of whatever nature and whether or not
            patentable or registrable under copyright or similar laws, which I
            may solely or jointly with others conceive or develop or reduce to
            practice, or cause to be conceived or developed or reduced to
            practice, during the period of time I am in the employ of the
            Company (collectively referred to as "Work Product"); and I further
            agree that the foregoing shall also apply to Work Product which
            relates the business of the Company or to the Company's anticipated
            business as of the end of my employment and which is conceived,
            developed, or reduced to practice during a period of one (1) year
            after the end of my employment. Without limiting the foregoing, I
            further acknowledge that all original works of authorship which are
            made by me (solely or jointly with others) within the scope of my
            employment and which are protectable by copyright are "works made
            for hire", as that term is defined in the United States Copyright
            Act.

     b)     MAINTENANCE OF RECORDS. I agree to keep and maintain adequate and
            current written records of all Work Product made by me (solely or
            jointly with others) during the term of my employment by the
            Company. The records will be in form of notes, sketches, drawings,
            and any other format that may be specified by the Company. The
            records will be available to and remain the sole property of the
            Company at all times.

     c)     PATENT AND COPYRIGHT REGISTRATIONS. I agree to assist the Company,
            or its designee, at the Company's expense, in every proper way to
            secure the Company's rights in the Work Product and any copyrights,
            patents, mask work rights or other intellectual property rights
            relating thereto in any and all countries, including the disclosure
            to the Company of all pertinent information and data with respect
            thereto and the execution of all applications, specifications,
            oaths, assignments and all other instruments which the Company shall
            deem necessary in order to apply for and obtain such rights and in
            order to assign and convey to the Company, its successors, assigns
            and nominees to sole and exclusive rights, title and interest in and
            to such Work Product, and any copyright, patents, mask work rights
            or other intellectual property rights relating thereto. This
            provision shall survive the termination of my employment by the
            Company, whether with or without cause.

3.   RETURNING COMPANY PROPERTY. I agree that, at any time upon request of the
     Company, and in any event at the time of the termination of my employment
     by Company, I will deliver to the Company (and will not keep in my
     possession or deliver to anyone else) any and all devices, records, data,
     notes, reports, proposals, lists, correspondence, specifications, drawings,
     blueprints, sketches, materials, equipment, other documents or property, or
     reproductions of any of the aforementioned items, containing Confidential
     Information or otherwise belonging to the Company, its successors or
     assigns, whether prepared by me or supplied to me by the Company.

4.   CONFLICTS

     a)     CONFLICTING EMPLOYMENT. I agree that, during the term of my
            employment by the Company, I will not engage in any other
            employment, occupation, consulting or other business activity
            related to the business in which the Company is now involved or

                                   Page 2 of 5
<Page>

            becomes involved during the term of my employment, nor will I engage
            in any other activities that conflict with my obligations to
            Company.

     B)     NO RESTRICTIONS. I am subject to no contractual or other restriction
            or obligation which will in any way limit my activities on behalf of
            the Company. I hereby represent and warrant to the Company that I do
            not claim rights in, or otherwise exclude from this Agreement, any
            Work Product (as defined above) or pervious work completed by me
            except the following (NOTE: IF NONE, PLEASE WRITE "NONE "; OR
            ADDITIONAL INFORMATION IS PROVIDED ON A SEPARATE SHEET, PLEASE SO
            INDICATE): _________________________________________________________
            ___________________________________________________________________.

5.   COVENANT AGAINST COMPETITION.

     a)     For the purposes of this Section:

            i)    "Competing Product" means any product, process, or service of
                  any person or organization other than the Company, in
                  existence or under development, (A) which is identical to,
                  substantially the same as, or an adequate substitute for any
                  product, process, or service of the Company, in existence or
                  under development, on which I work during the time of my
                  employment by the Company or about which I acquire
                  Confidential Information, and (B) which is (or could
                  reasonably be anticipated to be) marketed or distributed in
                  such a manner and in such a geographic area as to actually
                  compete with such product, process or services of the Company.

            ii)   "Competing Organization" means any person or organization,
                  including myself, engaged in, or about to become engaged in,
                  research on or the acquisition, development, production,
                  distribution, marketing, or providing of a Competing Product.

     b)     As a material inducement to the Company to employ me, and in order
            to protect the Company's Confidential Information and good will, I
            agree to the following stipulations:

            i)    For a period of twelve (12) months after termination of my
                  employment by the Company, whether with or without cause, I
                  will not directly or indirectly solicit or divert or accept
                  business relating in any manner to Competing Products or to
                  products, processes or services of the Company from any of the
                  customers or accounts of the Company with which I had any
                  contact as a result of my employment.

            ii)   For a period of twelve (12) months after termination of my
                  employment by the Company or its affiliates for any reason,
                  whether with or without cause, I will not render services,
                  directly or indirectly, as an employee, consultant or
                  otherwise, to any Competing Organization in connection with
                  research on or the acquisition,

                                   Page 3 of 5
<Page>

                  development, production, distribution, marketing, or
                  production of any Competing Product.

            iii)  For a period of twelve (12) months after termination of my
                  employment by the Company, whether with or without cause, I
                  will not directly or indirectly solicit or take away, or
                  attempt to solicit or take away, employees of the Company,
                  either for my own business or for any other person or entity.

6.   ENFORCEABILITY AND SEVERABILITY. In the event that any provision of this
     Agreement shall be determined to be unenforceable by any court of competent
     jurisdiction by reason of its extending for too great a period of time or
     over too large a geographic area or over too great a range of activities,
     it shall be interpreted to extend only over the maximum period of time,
     geographic area or range of activities as to which it may be enforceable.

     If any provision of this Agreement shall be determined to be invalid,
     illegal or otherwise unenforceable by any court of competent jurisdiction,
     the validity, legality and enforceability of the other provisions of this
     Agreement shall not be affected thereby. Any invalid, illegal or
     unenforceable provision of this Agreement shall be severable, and after any
     such severance, all other provisions hereof shall remain in full force and
     effect.

7.   BREACH.

     a)     EQUITABLE REMEDIES. I hereby expressly acknowledge that any breach
            or threatened breach of any of the terms and/or conditions set forth
            in this Agreement will result in substantial, continuing and
            irreparable injury to the Company. Therefore, I hereby agree that,
            in addition to any other remedy that may be available to the
            Company, the Company shall be entitled to injunctive or other
            equitable relief by a court of appropriate jurisdiction in the event
            of breach or threatened breach of the terms of this Agreement.

     b)     TOLLING. If any provisions of this Agreement are violated, then the
            time limitations set forth in this Agreement shall be extended for a
            period of time equal to the period of time during which such breach
            occurs, and, in the event the Company is required to seek relief
            from such breach before any court, board or other tribunal, then the
            time limitation shall be extended for a period of time equal to the
            pendency of such proceedings, including all appeals.

8.   GENERAL PROVISIONS

     a)     ARBITRATION OF DISPUTES. Any dispute arising out of this
            Agreement, my employment with the Company or termination
            therefrom, or any other relations with the Company, whether
            sounding in tort or contract, by statute or otherwise, shall be
            settled by arbitration in Boston, Massachusetts, in accordance
            with the Commercial Arbitration Rules of the American Arbitration
            Association before a single Arbitrator who shall have experience
            in the area of the matter in dispute. The Arbitrator may grant
            relief in the nature of injunctions (other than reinstatement) or
            other relief in such dispute or controversy. The decision of the
            arbitrator shall be final, conclusive and binding on the parties.
            Judgment may be entered on the Arbitrator's decision in any court
            having jurisdiction. The Company and I shall each pay one-half of
            the cost and expenses of such arbitration, and each party shall
            separately pay its or his/her own counsel fees and other costs in
            connection with the arbitration.

     b)     ENTIRE AGREEMENT. This Agreement supersedes all previous agreements,
            written or oral, between the Company and me relating to the subject
            matter of this Agreement, sets forth the entire agreement and
            understanding between the Company and me relating to the subject
            matter herein and merges all prior discussions between us with
            respect hereto. No modification of or amendment to this Agreement,
            nor any waiver of any rights under this Agreement, will be effective
            unless in writing signed by the party to be

                                   Page 4 of 5
<Page>

            charged. Any subsequent change or changes in my duties, job title or
            compensation will not affect the validity or scope of this
            Agreement.

     c)     SUCCESSORS AND ASSIGNS. This Agreement shall inure to the benefit of
            the Company and its legal representatives, successors and assigns,
            and shall be binding upon me and my heirs, legal representatives,
            successors and assigns.

     d)     GOVERNING LAW. This Agreement will be governed by the laws of the
            Commonwealth of Massachusetts, without regard to conflicts of law
            principles.

     e)     HEADINGS. The headings in this Stockholders Agreement are for
            convenience of reference only, and they shall not limit or otherwise
            affect the interpretation of any term or provision hereof.

I ACKNOWLEDGE THAT BEFORE PLACING MY SIGNATURE HEREUNDER, I HAVE READ ALL OF THE
PROVISIONS OF THIS AGREEMENT AND HAVE RECEIVED A COPY HEREOF TODAY. I FURTHER
ACKNOWLEDGE THAT ALTHOUGH THIS AGREEMENT HAS BEEN SIGNED AFTER THE COMMENCEMENT
OF MY EMPLOYMENT, IT APPLIES TO ANY AND ALL INFORMATION RECEIVED BY ME DURING MY
EMPLOYMENT.

Executed as a document under seal effective as of October 13, 1998.

                                  Signed:

                                  /s/ Guy Daniello
                                  ---------------------------------------------
                                  Guy Daniello

For NeuroMetrix, Inc.

/s/ Shai N. Gozani, M.D., Ph.D.
-------------------------------------------
Authorized Signature

                                   Page 5 of 5

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