Document:

Exhibit 10.1

 

 

 

271 Waverly Oaks Road, Suite 108

Waltham, MA 02452

April 25, 2016

 

Ryan R. Brenneman, CPA, JD

 

Dear Ryan:

 

Eyegate Pharmaceuticals, Inc. (the "Company")
is pleased to offer you employment with a start date as of April 25, 2015 (the "Start Date"). Your
role shall be to serve as Chief Financial Officer (CFO) of the Company. This letter is intended to summarize some of the terms
of your employment. We refer you to the policies, plans and practices of the Company for more details on the terms and conditions
of your employment.

 

Your employment is considered "at will";
both you and the Company have the right to terminate your employment at any time for any reason. This letter does not constitute,
and shall not be construed as, creating a contract or promise of employment for any set period of time.

 

You will report to Stephen From, the President and CEO of
the Company, and will be responsible for all tasks attendant to the role of CFO of an R&D stage specialty pharmaceutical
company, including but not limited to managing the financial statements, SEC reporting, audit of the financial statements,
internal controls and Sarbanes-Oxley compliance, accounting function management including budgets and forecasts and financial
strategy of the Company, and duties assigned to you by the CEO from time to time.

 

Your starting base salary is expected to be $9,615.39 every
two weeks (which annualizes to $250,000), less applicable withholdings and deductions. In addition, you will be eligible to earn
an incentive bonus/commission based on goals set by the Company shortly after your Start Date, with an annual target of up to thirty
percent 30% of your base salary. You will also be eligible to receive Incentive Stock Options to purchase 20,866 shares of the
Company's common stock within two years following the Start Date based on an evaluation of your performance, with such evaluation
and the timing of such award to be determined in the sole discretion of the Compensation Committee of the Board of Directors.

 

In addition to the base salary and bonus
opportunity, subject to approval by the Compensation Committee of the Board of Directors, you will be granted Incentive Stock
Options to purchase 41,732 shares of the Company's common stock (the "Options"), effective upon the
date of the next meeting of such committee after the date on which your employment with the Company commences (the
"Grant Date"). The Options will vest based on your continued employment with the Company as follows:
(a) one-third (1/3) of the shares subject the Options shall vest on the first anniversary of the Grant Date; provided
however, that upon a Change of Control occurring prior to the first anniversary of the Grant Date, a pro rata amount of such
shares calculated monthly based on the number of months passed since the Grant Date shall vest and become exercisable in full
upon such Change of Control (no partial vesting shall occur for partial months); and (b) thereafter, one twenty-fourth (1/24)
of the remaining shares on the last day of each of the twenty-four (24) consecutive months commencing with the month next
following the first anniversary of the Grant Date. The Options shall, in all events, be subject to the terms of the Company's
2014 Equity Incentive Plan (the "Plan"). "Change or Control" means (a) the closing
of any merger or consolidation of the Company with any other unrelated person or entity, or (b) the sale of all or
substantially all of the assets of the Company to another unrelated person or entity, or (c) the sale of more than fifty
percent (50%) of the total fair market value or total voting power of the stock of the Company to an unrelated party, such
that, in each case, the transaction has been approved by the Company's stockholders, and in which the stockholders of the
Company immediately prior to such merger, consolidation or sale shall, immediately after such merger, consolidation or sale,
own less than fifty percent (50%) of the issued and outstanding capital stock of the person or entity that is the
surviving company of any such merger or consolidation, or the acquirer in the case of any such sale of all or substantially
all of the assets of the Company. In the event of a discrepancy between an option award and this offer letter, the terms of
this offer letter shall prevail.

 

    	 

     

    

 

You will be eligible to participate in fringe benefit
plans as may be generally available to other Company employees. Policies applicable to other employees of the Company shall also
be applicable to you. Initially, this will include eligibility to participate in the Company's group health plan, reimbursement
for Company approved travel (in accordance with the Company's expense reimbursement policies), and accrual of up to twenty (20)
days per year of paid vacation time (accrued and useable in accordance with the Company's vacation policies). Vacation days stop
accruing after reaching the maximum allowable accrual for the year, after which time no vacation time will be accrued until used.

 

Employment with the Company is contingent on verification
of eligibility to work. Due to the Immigration Reform and Control Act of 1986, all employees hired after November 6, 1986, must
provide verification of employment eligibility prior to commencement of employment. We will need you to provide proper identification
on within the first three (3) days of work so that we can verify your employment eligibility. Your employment is also contingent
on your execution of the Company's standard Employee Nondisclosure, Noncompetition, Nonsolicitation and Inventions Agreement, a
copy of which is attached for your review and signature. Please sign and return the Employee Nondisclosure, Noncompetition, Nonsolicitation
and Inventions Agreement on or before your first day of employment.

 

Additionally, you represent that you are not subject
to and will not be subject to any agreements, restriction or obligations, including any noncompetition agreements or restrictions
or any nondisclosure or confidentiality agreement or restrictions, which prevent you from performing (or in any other way adversely
impact your ability to perform), your employment duties on behalf of the Company. Whether or not you are bound by the terms of
any such agreements, you agree that during your employment with the Company, you will not disclose or use, or induce anyone at
the Company to use, any confidential, proprietary or trade secret information or material belonging to any former employer or other
person or entity.

 

The terms set forth herein shall not be modified
except pursuant to a written agreement signed by both parties. This letter is governed by Massachusetts law.

 

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[Remainder of page
left blank intentionally]

 

 

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We look forward to your contributions towards the
growth of the Company.

Sincerely,

 

Eyegate Pharmaceuticals, Inc.

 

By: /s/ Stephen From                                 

Name: Stephen From

Its:       President and CEO

 

Receipt acknowledged:

 

/s/ Ryan R. Brenneman, CPA, JD                                   April
25, 2016

Ryan R. Brenneman, CPA, JD

 

 

    	 	4Exhibit 4.10

 

MASTER EXCLUSIVE SERVICE AGREEMENT

 

This Master Exclusive
Service Agreement (this “Agreement”) is entered into in Beijing as of

 

May13, 2015
by and among the following parties:

 

		(1)	Shanghai Zhongming Supply Chain Management Co., Ltd. (the “Zhongming”),
a wholly foreign-owned enterprise registered in Beijing, the People’s Republic of China (“China” or “PRC”),
under the laws of China; and

 

		(2)	Shanghai Zhongmin Supply Chain Management Co., Ltd. (the “Zhongmin”), a domestic
company registered in Beijing, China, under the laws of China.

 

(Each of Zhongming and Zhongmin
, a “Party”, and collectively the “Parties”).

 

RECITALS

 

WHEREAS, the
Parties intend to utilize their respective expertise and resources to further promote their existing business, and the businesses
that are developed during the term of this Agreement, and expand their market share; and

 

WHEREAS, the
Zhongming, together with the companies that are currently or during the term of this agreement directly or indirectly controlled
by the Zhongming, intends to provide certain services to Zhongmin; and Zhongmin agrees to accept such services only from the Zhongming.

 

NOW, THEREFORE,
in consideration of the premises and the representations, warranties, covenants and agreements herein contained, and intending
to be legally bound hereby, the Parties hereby agree as follows:

 

AGREEMENT

 

		1.	Provision of Services

 

		1.1	In accordance with the terms and conditions set forth in this Agreement, Zhongmin (referred to
as the “Service Receiving Party”) hereby irrevocably appoints and designates the Zhongming as its service provider
to provide the technical and business support services as set forth in Schedule 1.

 

		1.2	During the term of this Agreement, the Service Receiving Party shall not, without the Zhongming’s
written consent, directly and indirectly, obtain the same or similar services as provided under this Agreement from any third party,
or enter into any similar service agreement with any third party.

 

		2.	Zhongming’s
Power to Designate Service Provider; Statement of Work

 

		2.1	The Zhongming has the right to designate
and appoint, at its sole discretion, any entities affiliated with the Zhongming, including its wholly owned and holding
subsidiaries (together with the Zhongming, the “Service Providers”) to provide any and all services set forth
in Section 1 hereof.

 

		2.2	Service Providers shall provide the specific services under the scope listed in Schedule 1
to the Service Receiving Party.

 

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		3.	Service Fee and Payment

 

		3.1	The calculation and payment manners of the service fee are stipulated in Schedule 1 of this
Agreement. Nevertheless, the Zhongming shall have the right
to determine, at its reasonable discretion, the service fee and proper payment manners for the Service Receiving Party.

 

		3.2	If the Zhongming, in its reasonable discretion, determines that the fee calculation mechanism specified
shall no longer apply for any reasons at any time or from time to time during the term of this Agreement, the Zhongming shall have
the right to adjust the fee by giving a 10-day written notice to the Service Receiving Party.

 

		3.3	The Service Receiving Party shall procure its shareholders to pledge all of the equity interests
of the Service Receiving Party held by such shareholders in favor of the Zhongming to secure the service fee payable by the Service
Receiving Party under this Agreement.

 

		3.4	In accordance with the requirements of laws and business practices, the Service Receiving Party
shall prepare financial statements that meet the requirements of the Service Providers, and for the purpose of verifying the accuracy
of the amount of income and financial statements of the Service Receiving Party, the Service Receiving Party shall allow the Service
Providers or their designated auditors to audit relevant account books, and take notes and make copies of necessary account books
and records; the Service Receiving Party shall cooperate with the Service Providers and their parent company (directly or indirectly)
to carry out auditing of related party transactions and other kinds of auditing under applicable laws. The Service Receiving Party
shall provide relevant information and documents in respect of its operation, business, customers and labors to the Service Providers,
their parent company or their entrusted auditors. Also, the Service Receiving Party shall allow the parent company (directly or
indirectly) of the Service Providers to disclose such information and documents to satisfy the regulatory requirements of relevant
listing authority.

 

		4.	Intellectual Property Rights

 

		4.1	Any intellectual properties developed by performance of this Agreement, including but not limited
to copyrights, trademarks, patents, technical secrets, and know how, belong to the Service Providers, and the Service Receiving
Party shall enjoy no rights where they relate to intellectual properties other than those expressly provided herein.

 

		4.2	If a development is based on the intellectual properties owned by the Service Receiving Party,
the Service Receiving Party shall warrant and guarantee that such intellectual properties are flawless. Otherwise, the Service
Receiving Party shall bear all damages and losses caused to the Service Providers by any flaw of such intellectual properties.
If the Service Providers are to bear any liabilities to any third party thus caused, they have the right to recover all of their
losses from Service Receiving Party.

 

		4.3	The Service Receiving Party shall allow the Service Providers to
use all its intellectual properties for free.

 

		4.4	The Parties agree that this section shall survive the termination
or expiration of this Agreement.

 

		5.	Zhongming’s Financing Support 

 

		5.1	To ensure that the cash flow requirements with regard to the business operations of the Service
Receiving Party are met and/or to set off any loss accrued during such operations, the Zhongming agrees that it shall, to the extent
permissible under PRC law, through itself or its designated person, provide financial support to the Service Receiving Party. The
Zhongming’s financing support to the Service Receiving Party may take the form of bank entrusted loans or other forms permitted
under PRC law. Agreements for such financing support shall be executed separately and shall be
performed by the Parties to satisfy the requirements of the listing rules of the Hong Kong Exchanges and Clearing Limited (the
“Hong Kong Exchanges”), as well as relevant applicable laws and regulations.

 

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		6.	Representations and Warranties

 

		6.1	The Zhongming hereby represents and warrants as follows:

 

		(a)	It is a wholly foreign-owned enterprise duly incorporated and validly existing under PRC law;

 

		(b)	Its execution and performance of this Agreement are within its corporate power and business scope.
It has taken necessary corporate actions and obtained appropriate authorizations, and has obtained the necessary consents and approvals
from any third parties and government agencies. Its execution and performance of this Agreement do not violate the laws and contracts
binding upon it;

 

		(c)	Upon execution, this Agreement will constitute a legal, valid and binding obligation of the Zhongming
enforceable against the Zhongming in accordance with its terms.

 

		6.2	The Service Receiving Party hereby represents and warrants as follows:

 

		(a)	It is a legal person duly incorporated and validly existing under PRC law;

 

		(b)	Its execution and performance of this Agreement are within its entity power and business scope.
It has taken necessary entity actions and obtained appropriate authorizations, and has obtained the necessary consents and approvals
from any third parties and government agencies. Its execution and performance of this Agreement do not violate the laws and contracts
binding upon it;

 

		(c)	Upon execution, this Agreement will constitute a legal, valid and binding obligation of the Service
Receiving Party enforceable against the Service Receiving Party in accordance with its terms; and

 

		(d)	It has taken all necessary measures and executed all necessary documents to ensure that, in the
event that the registered shareholder of the Service Receiving Party dies, loses capacity, becomes bankrupt, divorce or in other
situation under which may affect the registered shareholder’s holding of the equity interests of the Service Receiving Party,
any successor of the registered shareholder shall be deemed as the party to this Agreement, and shall assume and undertake all
rights and obligations under the terms of this Agreement.

 

		7.	Confidentiality

 

		7.1	The Service Receiving Party agrees to take all reasonable steps to protect and maintain the confidentiality
of the confidential data and information received by the Service Receiving Party in connection with the performance of this Agreement
(collectively, the “Confidential Information”). The Service Receiving Party shall not disclose, give or transfer
any Confidential Information to any third party without the Zhongming’s prior written consent. Upon termination of this Agreement,
the Service Receiving Party shall, at the Zhongming’s request, return any and all documents, information or software containing
any of such Confidential Information to the Zhongming or destroy it, and delete all of such Confidential Information from any memory
devices, and cease to use such Confidential Information.

 

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		7.2	The Parties agree that this section shall survive the termination
or expiration of this Agreement.

 

		8.	Effective Date and Term

 

		8.1	This Agreement shall be signed and take effect as of the date first set forth above.

 

		8.2	This Agreement shall remain effective unless terminated as provided herein. Notwithstanding the
foregoing provisions, i) the Zhongming shall have the right to terminate this Agreement at any time with a written notice to Service
Receiving Party given thirty (30) days in advance, whereas the Service Receiving Party shall not have the right to terminate this
Agreement; and ii) This Agreement shall be terminated upon the transfer of all the equity interests of Service Receiving Party
to the Zhongming and/or a third party designated by the Zhongming pursuant to the Exclusive Option Agreement.

 

		8.3	This Agreement shall be automatically terminated upon the event that it becomes permitted under
PRC laws for the Zhongming to directly hold the equity interests of the Service Receiving Party, and the Zhongming or its designated
party receives all the equity interests of the Service Receiving Party pursuant to the Exclusive Option Agreement. The termination
or earlier termination of this Agreement due to any reason shall not exempt any party’s payment obligations (including but
not limited to Service Fee) and any liability for breach the contract incurred before the termination of this Agreement. The Service
Receiving Party shall pay the Service Fee incurred before the termination of this Agreement to the Zhongming within 5 business
days after the termination of this Agreement.

 

		9.	Governing Law

 

		9.1	This Agreement shall be construed in accordance with and governed by the laws of the PRC.

 

		10.	Dispute Resolution

 

Any dispute or claim arising
out of or in connection with or relating to this Agreement shall be resolved by the Zhongming and Zhongmin in good faith through
negotiations. In case no resolution can be reached by the Zhongming and Zhongmin, such dispute shall be submitted to the Shanghai
International Economic and Trade Arbitration Commission for arbitration in accordance with its rules of arbitration in effect at
the time of applying for such arbitration and the place of arbitration shall be in Shanghai The arbitral tribunal or the arbitrators
shall have the authority to award any remedy or relief in accordance with the terms of this Agreement and applicable PRC laws,
including provisional and permanent injunctive relief (such as injunctive relief with respect to the conduct of business or to
compel the transfer of assets), specific performance of any obligation created hereunder, remedies over the equity interests or
land assets of Zhongmin and winding up orders against Zhongmin. The arbitral award shall be final and binding upon both Parties.

 

To the extent permitted under
applicable PRC laws, each of the Parties shall have the right to seek interim injunctive relief or other interim relief from a
court of competent jurisdiction in support of the arbitration when formation of the arbitral tribunal is pending or under appropriate
circumstances. For this purpose, the Parties agree that, to the extent not against applicable laws, the courts of Hong Kong, the
courts of the Cayman Islands, the courts of PRC and the courts of the places where the principal assets of Zhongmin are located
shall all be deemed to have jurisdiction.

 

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		11.	Notices

 

Notices or
other communications required to be given by any party pursuant to this Agreement shall be written in English and Chinese and delivered
personally or sent by registered mail or postage prepaid mail or by a recognized courier service or by facsimile transmission to
the address of each relevant party as specified by such party from time to time. The date when a notice is deemed to be duly served
shall be determined as follows: (a) a notice delivered personally is deemed duly served upon delivery; (b) a notice sent by mail
is deemed duly served on the tenth (10th) day after the date when the postage prepaid registered airmail is posted (as evidenced
by the postmark), or on the fourth (4th) day after the date when the notice is delivered to an internationally-recognized courier
service agency; and (c) a notice sent by facsimile transmission is deemed duly served upon receipt as evidenced by the time shown
in the transmission confirmation for the relevant documents.

 

		12.	Indemnities and Remedies

 

		12.1	Either Party shall forthwith on demand indemnify the other Party against any claim, loss, liability
or damage (“Loss”) which such Party shall incur as a consequence of any
breach by the other Party of this Agreement provided that neither Party shall be liable to indemnify the other Party for any Loss
to the extent that such Loss arises from the willful misconduct, breach of applicable law, regulation or contractual obligation
or from the material negligence of the other Party or its directors, officers, employees, or agents.

 

		12.2	The Parties agree that this section shall survive the termination
or expiration of this Agreement.

 

		13.	Assignment

 

		13.1	The Service Receiving Party shall not assign any of its rights or obligations under this Agreement
to any third party without the prior written consent of the Zhongming.

 

		13.2	The Service Receiving Party hereby agrees that the Zhongming may assign its rights and obligations
under this Agreement, only subject to a written notice to Zhongmin.

 

		14.	Severability

 

If any provision of this Agreement
is judged to be invalid or unenforceable because it is inconsistent with applicable laws, such invalidity or unenforceability shall
be only with respect to such laws, and the validity, legality and enforceability of the other provisions hereof shall not be affected.

 

		15.	Amendment or Supplement

 

		15.1	Any amendment or supplement to this Agreement shall be made by the Parties in writing. The amendments
or supplements duly executed by each party shall form an integral part of this Agreement and shall have the same legal effect as
this Agreement.

 

		15.2	In the event that The Stock Exchange of Hong Kong Limited or other supervision and administration
institution provides any comments to this Agreement, or upon any changes to the Rules Governing the Listing of Securities on The
Stock Exchange of Hong Kong Limited or relevant requirements where they relate to this Agreement, the Parties shall amend this
Agreement accordingly.

 

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		16.	

 

Each Party shall pay any tax,
expenses and fees incurred thereby or levied thereon in accordance with the laws of China in connection with the preparation, execution
and performance of this Agreement.

 

		17.	Counterparts

 

This Agreement shall be executed
in two originals by both Parties, with each of the Zhongming and Zhongmin holding one original. All originals shall have the same
legal effect. The Agreement may be executed in one or more counterparts.

 

		18.	Languages

 

This Agreement is written in
English and Chinese. Both language versions shall have equal validity. In case of any discrepancy between the English version and
the Chinese version, the Chinese version shall prevail.

 

[Signature page follows]

 

 

    6 

     

    

 

IN WITNESS WHEREOF, the Parties have duly
executed this Agreement on the date appearing at the head hereof.

 

Shanghai Zhongming Supply Chain Management
Co.,Ltd.

Authorized Representative:

 

Signature: /s/_Shanghai Zhongming Supply
Chain Management Co.,Ltd.

Seal: (Seal)

 

Shanghai Zhongmin Supply Chain Management
Co., Ltd.

Authorized Representative:

 

Signature: /s/Shanghai Zhongmin Supply
Chain Management Co., Ltd.

Seal: (Seal)

 

     

     

    

  

Schedule
1

Contents of Service, Calculation and Payment of the Service Fee

 

		1.	Contents of Service

 

		1.1	Providing technology development and transfer, and technical consulting services:

 

		1.2	Providing occupation and pre-occupation staff training services;

 

		1.3	Providing public relation services;

 

		1.4	Providing market investigation, research and consulting services;

 

		1.5	Providing mid or short-term market development and market planning services;

 

		1.6	Providing human resource management and internal information management;

 

		1.7	Providing network development, upgrade and daily maintenance;

 

		1.8	Providing sale services of self-produced products;

 

		1.9	Licensing of software;

 

		1.10	Providing maintenance services in respect of computer software and hardware system, database and
computer servers;

 

		1.11	Other services determined from time to time by the Zhongming according to the need of business
and capacity of the Service Providers.

 

		2.	Calculation and Payment of Service Fee

 

		2.1	The service fee shall be equal to 100% of the audited consolidated net profits of the Service Receiving
Party. Notwithstanding the foregoing provision, the Zhongming may adjust the service fee at its sole discretion in accordance with
provision of Clause 2.2 below and the requirements of relevant governmental authorities, with reference to the working capital
requirements of the Service Receiving Party. The Service Receiving Party shall
accept such adjustments.

 

		2.2	The specific amount of such fee shall be determined by Zhongming after taking account of the following
factors, and Zhongming shall send Zhongmin written confirmations with respect to the amounts of the service fee:

 

		(a)	The technical difficulty and complexity of the services provided by the Service Providers;

 

		(b)	The time spent by employees of the Service Providers concerning the services;

 

		(c)	The contents and commercial value of the services provided by the Service Providers;

 

		(d)	The benchmark price of similar services in the market.

 

    Sch-1-1 

     

    

  

		2.3	The Service Providers will calculate service fee payable on an annual basis and send to the Service
Receiving Party corresponding invoices. The Service Receiving Party shall pay the fee to the bank account designated by the Service
Providers within 10 business days after receipt of such invoices, and send a copy of the remittance certificate by facsimile or
mail to the Service Providers within 10 business days after payment. The Service Providers shall issue a receipt within 10 business
days after receipt of the service fee. Notwithstanding the foregoing provisions, the Zhongming may adjust the time and method of
the payment of service fee at its sole discretion. The Service Receiving Party shall accept such adjustments.

 

    Sch-1-2

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