Document:

Exhibit
10.39

***Text
Omitted and Filed Separately

with the Securities and Exchange Commission.

Confidential Treatment Requested

Under 17 C.F.R. Sections 200.80(b)(4)

and 240.24b-2.

FIFTH AMENDMENT

TO THE

COLLABORATIVE RESEARCH AND LICENSE AGREEMENT

THIS FIFTH AMENDMENT
TO THE COLLABORATIVE RESEARCH AND LICENSE AGREEMENT (the “Fifth Amendment”) is
entered into as of October 29, 2006 (the “Fifth Amendment Effective Date”) by and
between SENOMYX, INC.
(“Senomyx”),
a Delaware corporation, having a principal place of business at 11099 North
Torrey Pines Road, La Jolla, California 92037, and KRAFT FOODS GLOBAL, INC.,
a Delaware corporation (“Kraft”)
having offices at 801 Waukegan Road, Glenview, IL 60025.

WHEREAS,
Senomyx and Kraft entered into that certain Collaborative Research and License
Agreement dated as of December 6, 2000, as amended by that certain First
Amendment dated May 2, 2002, that certain Second Amendment dated April 29, 2005,
that certain Third Amendment dated July 29, 2005, that certain Fourth Amendment
dated December 9, 2005 and that certain Amended and Restated Fourth Amendment
dated December 9, 2005 (collectively, the “Agreement”);

 WHEREAS, within [...***...]
days of the Fifth Amendment Effective Date, Senomyx shall submit to Kraft a written
report regarding [...***...], which the Steering Committee has determined to be
reasonable within the meaning of Section 3.1.1(C)(ii), thereby completing Senomyx’s
obligations under the [...***...] Phase (capitalized terms used but not otherwise
defined in this Fifth Amendment shall have the meanings given such terms in the
Agreement); and

WHEREAS,
in recognition of Senomyx’s completion of its obligations under the [...***...], Senomyx
and Kraft wish to amend the Agreement to shift the remaining research funding from
the [...***...] Phase to the [...***...] Phase;

NOW, THEREFORE, in consideration of the
foregoing premises and of the covenants, representations and agreements set
forth below, the parties hereby agree to amend the Agreement as follows:

1.                                      Senomyx,
within [...***...] days of the Fifth Amendment Effective date, shall submit to
Kraft a written report regarding [...***...]. Upon receipt thereof by Kraft, the
parties agree that Senomyx’s obligations under the [...***...] Phase shall be completed
pursuant to Section 3.1.1(C) of the Agreement. 
The parties’ rights and obligations with respect to the [...***...] Phase of
the Collaborative Program under Sections 3, 9 and 10 of the Agreement will
continue only with respect to [...***...].

2.                                      Pursuant
to Section 9.2(B) of the Agreement, Kraft will pay Senomyx a milestone payment of
[...***...] within [...***...] days of the Fifth Amendment Effective Date.

3.                                      Section
3.1.1(B) of the Agreement is hereby amended and restated as follows:

 ***Confidential Treatment Requested
 

“During the Collaborative Period which will continue
through [...***...] for the [...***...] Phase, Kraft will evaluate [...***...] and may
select [...***...] for further development by notifying Senomyx of such selection
in writing on or before expiration of the Collaborative Period.  Upon such notification, [...***...] will become a
[...***...] Compound.”

4.                                      Section
9.1 of the Agreement is hereby modified such that all research funding from the
[...***...] Phase is shifted to the [...***...] Phase as of the Fifth Amendment
Effective Date.  Accordingly, beginning
on December 9, 2006 and through the end of the December 8, 2007, Kraft will pay
Senomyx at an annual rate of [...***...] for the [...***...] Phase.  From December 9, 2007, Kraft will pay Senomyx
at an annual rate of [...***...] through the end of the Collaborative Period for
the [...***...] Phase.  These payments will
be made [...***...] and on an [...***...], provided that, with respect to the change in
funding rate, payments for any period at a particular funding rate for less
than one [...***...] of the Collaborative Period will be based on the pro rata
portion of the [...***...] installment based on the actual number of days in such [...***...]
at the applicable funding rate. Kraft shall have the right to terminate the [...***...]
Phase of the Agreement by providing Senomyx with thirty (30) days advance
written notice prior to the second anniversary date (December 9, 2007) of the
Effective Date of the Restated Fourth Amendment 
(the “No Go Notification”).

5.                                      Except
as specifically amended by this Fifth Amendment, the terms and conditions of
the Agreement shall remain in full force and effect.

6.                                      This
Fifth Amendment will be governed by the laws of the State of California, as
such laws are applied to contracts entered into and to be performed entirely
within such State.

7.                                      This
Fifth Amendment may be executed in two or more counterparts, each of which
shall be deemed an original, but all of which together shall constitute one and
the same instrument.

IN WITNESS WHEREOF, the parties, through their authorized officers, have executed this Fifth Amendment as of the Fifth Amendment Effective Date.

	
  SENOMYX, INC.

  	
   

  	
  KRAFT FOODS
  GLOBAL, INC.

  
	
   

  	
   

  	
   

  
	
  By:

  	
  /s/ Kent Snyder

  	
   

  	
  By:

  	
  /s/ Todd Abraham

  
	
   

  	
   

  	
   

  
	
  Name: Kent Snyder

  	
   

  	
  Name: Todd Abraham

  
	
  Title: President and Chief Executive Officer

  	
   

  	
  Title: VP Global Research & Technology Strategy

  
	
   

  	
   

  	
   

  
	
  Date:

  	
  October 31, 2006

  	
   

  	
  Date:

  	
  November 6, 2006

  

 

 ***Confidential Treatment RequestedEXHIBIT
10.40

March
13, 2006

Sharon Wicker

6420 East Bay Lane

Richland, MI 49083

Dear Sharon:

Thank you for spending time with me and the Senomyx
team these past few weeks to discuss the exciting opportunity we have for you
as we build our organization.  We all
believe this position is an ideal match for your talents and experience and
that you will be a great fit for our executive team.

We are pleased to extend to you an offer to join
Senomyx, Inc. (the “Company”) as
our Senior Vice President of Commercial Development
and Chief Strategy Officer. 
This position will report directly to me.  As a new team member, you have the
opportunity to help create a legacy through your valuable contributions, and I
look forward to your first day, April 24, 2006.

The following terms apply and will constitute your
employment agreement with the Company (the “Agreement”).

1.                                      EMPLOYMENT.

1.1          Term.  The term of this
Agreement shall begin on your first day of work for the Company, which is
scheduled for April 24, 2006, and shall continue until terminated in accordance
with Section 4 herein.

1.2          Title.  You shall have the title of Senior Vice
President of Commercial Development and Chief Strategy Officer of the Company
and shall report to the Chief Executive Officer of the Company (the “CEO”).  You shall
serve in such other capacity or capacities as the Company may from time to time
prescribe.

1.3          Duties.  You shall do and perform all services,
acts or things necessary or advisable to manage and conduct the business of the
Company and which are normally associated with the position of Senior Vice
President of Commercial Development and Chief Strategy Officer, consistent with
the bylaws of the Company.  Your duties
will also include participation in Board of Directors meetings and senior level
management committee meetings as specified by the CEO.  As a Company employee, you will be expected
to comply with Company policies and acknowledge in writing that you have read
the Company’s Employee Handbook.  The
Company’s Employee Handbook may be modified from time to time at the sole
discretion of the Company.

 1
 

1.4          Location.  Unless otherwise agreed in writing, you shall
perform services pursuant to this Agreement at the Company’s offices located in
San Diego, California, or at any other place at which the Company maintains an
office; provided, however, that the Company may from time to time require you
to travel temporarily to other locations in connection with the Company’s
business.

2.                                      LOYAL AND
CONSCIENTIOUS PERFORMANCE; NONCOMPETITION.

2.1          Loyalty.  During your employment by the Company you
shall devote your full business energies, interest, abilities and productive
time to the proper and efficient performance of your duties under this
Agreement.

2.2          Covenant not to Compete.  Except with the prior written consent of the
Company’s Board of Directors (the “Board”), you
will not, while employed by the Company, or during any period during which you
are receiving compensation or any other consideration from the Company, engage
in competition with the Company  and/or any
of its affiliates, subsidiaries, or joint ventures currently existing or which
shall be established during your employment by the Company (collectively, “Affiliates”) either directly or indirectly, in any manner
or capacity, as adviser, principal, agent, affiliate, promoter, partner,
officer, director, employee, stockholder, owner, co-owner, consultant, or
member of any association or otherwise, in any phase of the business of
developing, manufacturing and marketing of products or services which are in
the same field of use or which otherwise compete with the products or services
or proposed products or services of the Company and/or any of its Affiliates.

2.3          Agreement not to
Participate in Company’s Competitors. 
During your employment by the Company, you agree not to acquire, assume
or participate in, directly or indirectly, any position, investment or interest
known by you to be adverse or antagonistic to the Company, its business or
prospects, financial or otherwise or in any company, person or entity that is,
directly or indirectly, in competition with the business of the Company or any
of its Affiliates.  Ownership by you, as
a passive investment, of less than two percent (2%) of the outstanding shares
of capital stock of any corporation with one or more classes of its capital
stock listed on a national securities exchange or publicly traded on the Nasdaq
Stock Market or in the over-the-counter market shall not constitute a breach of
this paragraph.

3.                                      COMPENSATION.

3.1          Base Salary.  The Company shall pay you a base salary of
two hundred seventy-five thousand dollars ($275,000) per year, less payroll
deductions and all required withholdings, payable in regular periodic payments
in accordance with Company policy.  Such
base salary shall be prorated for any partial year of employment on the basis
of a 365-day fiscal year.

3.2          Bonus.  In addition to your base salary, you will be
eligible to receive an annual discretionary bonus of up to forty percent (40%)
of your then current base salary based

 2
 

upon your performance
against specific milestones to be defined by the CEO.  In addition, you will be entitled to
guaranteed bonus payments as follows: 
$50,000 to be paid within ten (10) days of the commencement of your
employment hereunder; $33,000 to be paid within ten (10) days of the one (1)
year anniversary of the commencement of your employment hereunder; and $17,000
to be paid within ten (10) days of the two (2) year anniversary of the
commencement of your employment hereunder (so long as, in each case, you have
remained continuously employed with the Company since your employment start
date hereunder).

3.3          Stock Options.  Upon commencement of your employment
hereunder, you shall be granted pursuant to the terms of the Company’s 1999
Equity Incentive Plan, as amended (the “Plan”), an
option to purchase up to 150,000 shares of the common stock of the Company (the
“Option”).  The Option shall be an incentive stock option
to the extent permitted by applicable Federal income tax law.  The exercise price of the Option will be
equal to the fair market value of the common stock on the date of the grant.
The Option will vest over four (4) years according to the following schedule
(i) twenty-five percent (25%) of the total shares will vest upon the first
anniversary of the commencement of your employment with the Company; (ii) 1/48th of the total shares subject to the Option will
vest at the end of each one-month anniversary beginning at the end of the one
year and will continue to vest over the following three year period.  The Option will be governed by a separate
Stock Option Agreement and the Plan.

3.4          Option Rights Upon Change of Control.  The Plan contains a “double trigger” vesting
acceleration provision such that, as more fully specified in the Plan, if your
employment terminates under specified circumstances following a change in
control of the Company (as defined in the Plan) such option shall immediately
become 100% vested and exercisable in full.

3.5          Employment Taxes.  All of your compensation shall be subject to
customary withholding taxes and any other employment taxes as are commonly
required to be collected or withheld by the Company.

3.6          Vacation; Benefits.  You will be entitled to up to seventeen (17)
days of Paid Time Off (“PTO”) per year.  In addition, you shall, in accordance with
Company policy and the terms of the applicable plan documents, be eligible to
participate in benefits under any executive benefit plan or arrangement which
may be in effect from time to time and made available to the Company’s
executive or key management employees.

3.7          Relocation.  The Company will pay up to $30,000 (the “Relocation Allowance”) for actual expenses for movement of
household goods by a relocation company selected by the Company (the “Relocation Expenses”). 
The Company will also grant a signing bonus (in addition to the bonuses
provided for in Section 3.2) in the net amount of $50,000 (the “Home Sale Bonus”) intended to cover the commission on the
sale of your home and the fees associated with the purchase of your new home
(collectively, the “Home Sale Expenses”),
which is to be paid within 10 days of your start date with the Company.  However, for avoidance of doubt in the event
such $50,000 payment is not sufficient to cover the commission on the sale

 3
 

of your home and fees
associated with the purchase of your new home, the Company will not increase
the amount of such signing bonus. The Home Sale Bonus is intended to be net of
all taxes, and you agree to work with the Company to establish the related
necessary “gross-up” calculation.   In addition, the Company will provide
$20,000 (the “Moving Expense Allowance”) for
temporary housing, moving related expenses, or transportation of you and your
family (collectively, “Moving Expenses”),
less standard withholdings and deductions. 
You may elect to apply all or a portion of your Relocation Expense
Allowance, Home Sale Bonus and/or Moving Allowance against your Relocation
Expenses, Home Sale Expenses and/or Moving Expenses.  All payments and expenses paid by the company
may be considered taxable income to you and be subjected to federal and state
taxes via payroll.  Please contact your
tax consultant to determine which expenses may be used as itemized deductions on
your income tax return.  Please contact
Shanna Lepore, Director, Human Resources, to discuss further details.

4.                                      TERMINATION.

4.1          Termination By the
Company.  Your employment with the
Company may be terminated under the following conditions:

4.1.1       Termination for Death or
Disability.  Your employment with the
Company shall terminate effective upon the date of your death or Complete Disability.  “Complete
Disability” shall mean the inability of you to perform your
duties under this Agreement because you have become permanently disabled within
the meaning of any policy of disability income insurance covering employees of
the Company then in force.  In the event
the Company has no policy of disability income insurance covering employees of
the Company in force when you become disabled, the term Complete Disability shall mean the inability of the you to perform
your duties under this Agreement by reason of any incapacity, physical or
mental, which the Board, based upon medical advice or an opinion provided by a
licensed physician acceptable to the Board, determines to have incapacitated
you from satisfactorily performing all of your usual services for the Company
for a period of at least ninety (90) days during any twelve (12) month period
(whether or not consecutive).  Based upon
such medical advice or opinion, the determination of the Board shall be final
and binding and the date such determination is made shall be the date of such
Complete Disability for purposes of this Agreement.  If your employment shall be terminated by
death or Complete Disability, the Company shall pay to you, and/or your heirs,
your base salary and accrued and unused vacation benefits earned through the
date of termination at the rate in effect at the time of termination, less
standard deductions and withholdings, and the Company shall thereafter have no
further obligations to you and/or your heirs under this Agreement.

4.1.2       Termination by the Company
For Cause.  The Company may terminate
your employment under this Agreement for Cause.  “Cause”  for the
Company to terminate your employment shall mean the occurrence of any of the
following events:

(i)            your substantial
and repeated failure to satisfactorily perform your job duties which in the
reasonable good faith determination of the Company demonstrates gross

 4
 

unfitness to serve
the Company, such as continued flagrant absences from the Company and
demonstrable and substantial lapses of duty;

(ii)           your refusal or
failure to follow lawful directions of the CEO;

(iii)         your conviction of a
felony or a crime involving moral turpitude;

(iv)          your engaging or in
any manner participating in any activity which is directly competitive with or
injurious to the Company  or any of
its Affiliates or which violates any material provisions of Section 5 hereof or
your Proprietary Information and Inventions Agreement with the Company; or

(v)            your commission of
any fraud against the Company, its Affiliates, employees, agents, collaborators
or customers or use or intentional appropriation for your personal use or
benefit of any funds or properties of the Company.

If your employment
shall be terminated by the Company for Cause, the Company shall pay the your
base salary and accrued and unused vacation benefits earned through the date of
termination at the rate in effect at the time of termination, less standard
deductions and withholdings, and the Company shall thereafter have no further
obligations to you under this Agreement.

4.1.3       Termination by the Company
Without Cause.  You shall be an
at-will employee.  The Company may
terminate your employment under this Agreement at any time and for any reason
or no reason.  However, if the Company
terminates your employment without Cause (i) the Company shall pay you your
base salary and accrued and unused vacation earned through the date of
termination at the rate then in effect, less standard deductions and
withholdings and (ii) the Company shall continue to pay to you as severance, on
the Company’s regular pay days, your base salary then in effect for a period of
six (6) months following the date of termination, less standard deductions and
withholdings; provided that in order to be eligible for said severance payments
pursuant to the foregoing clause (ii) you shall be required to execute and
deliver to the Company a release of claims substantially in the form of Exhibit
A and you shall not be eligible to receive any such severance payment or
acceleration until said release shall become effective.

4.2          Termination By You.  You may resign your employment upon thirty
(30) days written notice to the Company, delivered to the CEO.  Upon such resignation, the Company shall pay
you your base salary and accrued and unused vacation earned through the date
upon which the Company, in its sole discretion, accepts such resignation, and you
shall not be entitled to any other benefit or compensation and the Company
shall have no further obligations to you under this Agreement.

4.3          Termination by Mutual
Agreement of the Parties.  Your
employment pursuant to this Agreement may be terminated at any time upon mutual
agreement, in writing.  Any such
termination of employment shall have the consequences specified in such
writing.

 5
 

4.4          Survival of Certain
Provisions.  Sections 2.2 and 5 shall
survive the termination of this Agreement.

5.                                      CONFIDENTIAL
AND PROPRIETARY INFORMATION; NONSOLICITATION.

5.1          As a condition of
employment you agree to execute and abide by the Company’s standard Proprietary
Information and Inventions Agreement, attached hereto as Exhibit B.

5.2          While employed by
the Company and for one (1) year thereafter, you agree that in order to protect
the Company’s trade secrets and confidential and proprietary information from
unauthorized use, you will not, either directly or through others, solicit or
attempt to solicit any employee, consultant or independent contractor of the
Company to terminate his or her relationship with the Company in order to
become an employee, consultant or independent contractor to or for any other
person or business entity.

6.                                      ASSIGNMENT
AND BINDING EFFECT.

This
Agreement shall be binding upon and inure to the benefit of you and your heirs,
executors, personal representatives, assigns, administrators and legal
representatives.  Because of the unique
and personal nature of your duties under this Agreement, neither this Agreement
nor any rights or obligations under this Agreement shall be assignable by
you.  This Agreement shall be binding
upon and inure to the benefit of the Company and its successors, assigns and
legal representatives.

7.                                      CHOICE OF
LAW.

This
Agreement shall be construed and interpreted in accordance with the internal
laws of the State of California.

8.                                      INTEGRATION.

This
Agreement, including Exhibits A and B, contains the complete, final and
exclusive agreement of the Parties relating to the terms and conditions of your
employment and the termination of your employment, and supersedes all prior and
contemporaneous oral and written employment agreements or arrangements between
the Parties. To the extent this Agreement conflicts with the Proprietary
Information and Inventions Agreement attached as Exhibit A hereto, the
Proprietary Information and Inventions Agreement controls.

9.                                      AMENDMENT.

This
Agreement cannot be amended or modified except by a written agreement signed by
you and the Chairman of the Board of the Company.

 6
 

10.                               WAIVER.

No term,
covenant or condition of this Agreement or any breach thereof shall be deemed
waived, except with the written consent of the Party against whom the wavier is
claimed, and any waiver or any such term, covenant, condition or breach shall
not be deemed to be a waiver of any preceding or succeeding breach of the same
or any other term, covenant, condition or breach.

11.                               SEVERABILITY.

The
finding by a court of competent jurisdiction of the unenforceability,
invalidity or illegality of any provision of this Agreement shall not render
any other provision of this Agreement unenforceable, invalid or illegal.  Such court shall have the authority to modify
or replace the invalid or unenforceable term or provision with a valid and
enforceable term or provision which most accurately represents the Parties’ intention with respect to the
invalid or unenforceable term or provision.

12.                               INTERPRETATION;
CONSTRUCTION.

The
headings set forth in this Agreement are for convenience of reference only and
shall not be used in interpreting this Agreement.  This Agreement has been drafted by legal
counsel representing the Company, but you have been encouraged to consult with,
and have consulted with, your own independent counsel and tax advisors with
respect to the terms of this Agreement. 
The Parties acknowledge that each Party and its counsel has reviewed and
revised, or had an opportunity to review and revise, this Agreement, and any
rule of construction to the effect that any ambiguities are to be resolved
against the drafting party shall not be employed in the interpretation of this
Agreement.

13.                               REPRESENTATIONS
AND WARRANTIES.

You
represent and warrant that you are not restricted or prohibited, contractually
or otherwise, from entering into and performing each of the terms and covenants
contained in this Agreement, and that your execution and performance of this
Agreement will not violate or breach any other agreements between you and any
other person or entity.

14.                               COUNTERPARTS.

This
Agreement may be executed in two counterparts, each of which shall be deemed an
original, all of which together shall contribute one and the same instrument.

15.                               LITIGATION
COSTS.

Should
any claim be commenced between the Parties or their personal representatives
concerning any provision of this Agreement or the rights and duties of any
person in relation to this Agreement, the Party prevailing in such action shall
be entitled, in addition to such other relief as may be granted to a reasonable
sum as and for that Party’s attorney’s fees in such action.

 7
 

16.                               ELIGIBILITY.

As
required by law, this offer and Agreement is subject to satisfactory proof of
your right to work in the United States.

If you
accept employment on the terms described above, please sign and date this
letter in the space provided below and return it to me no later than March 21,
2006.  After such date this offer shall
lapse.

Sharon,
please feel free to call me if you have any questions, or if we can be of
additional assistance.  We feel strongly
about your fit for this position and believe that your presence on our team
will greatly enhance our ability to succeed. 
Welcome to Senomyx – we look forward to having you as a member of our
team!

Sincerely,

	
  Senomyx, Inc.

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
  /s/ Kent Snyder

  	
   

  	
   

  	
   

  
	
  Kent Snyder, President
  and CEO

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
  Agreed
  and Accepted:

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
  /s/ Sharon
  Wicker

  	
   

  	
   

  	
   

  
	
  Sharon Wicker

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
  Dated:

  	
  3/20/06

  	
   

  	
   

  	
   

  
					

 

 8

EXHIBIT A

RELEASE
AND WAIVER OF CLAIMS

In
consideration of the payments and other benefits set forth in Section 4.1.3 of
the Offer of Employment letter dated March 14, 2006 (the “Agreement”), to which this form is attached, I, Sharon
Wicker, hereby furnish Senomyx, Inc. (the “Company”),
with the following release and waiver (“Release and Waiver”).

I
hereby generally and completely release the Company and its directors,
officers, employees, shareholders, partners, agents, attorneys, predecessors,
successors, parent and subsidiary entities, insurers, Affiliates, and assigns
from any and all claims, liabilities and obligations, both known and unknown,
that arise out of or are in any way related to events, acts, conduct, or
omissions occurring prior to my signing this Release and Waiver.  This general release includes, but is not
limited to: (1) all claims arising out of or in any way related to my
employment with the Company or the termination of that employment; (2) all
claims related to my compensation or benefits from the Company, including
salary, bonuses, commissions, vacation pay, expense reimbursements, severance
pay, fringe benefits, stock, stock options, or any other ownership interests in
the Company; (3) all claims for breach of contract, wrongful termination,
and breach of the implied covenant of good faith and fair dealing; (4) all
tort claims, including claims for fraud, defamation, emotional distress, and
discharge in violation of public policy; and (5) all federal, state, and local
statutory claims, including claims for discrimination, harassment, retaliation,
attorneys’ fees, or other claims arising under the federal Civil Rights Act of
1964 (as amended), the federal Americans with Disabilities Act of 1990, the
federal Age Discrimination in Employment Act of 1967 (as amended) (“ADEA”), and the California Fair Employment and Housing Act
(as amended); provided, however, that this release shall not relieve the
Company of any of its obligations under the Agreement or pursuant to any
written stock option agreement granted to me pursuant to the Company’s equity
incentive plans.

I
also acknowledge that I have read and understand Section 1542 of the California
Civil Code which reads as follows:  “A general release does not extend to claims which the creditor does not
know or suspect to exist in his favor at the time of executing the release,
which if known by him must have materially affected his settlement with the
debtor.”  I hereby
expressly waive and relinquish all rights and benefits under that section and
any law of any jurisdiction of similar effect with respect to any claims I may
have against the Company.

I
acknowledge that, among other rights, I am waiving and releasing any rights I
may have under ADEA, that this Release and Waiver is knowing and voluntary, and
that the consideration given for this Release and Waiver is in addition to
anything of value to which I was already entitled as an executive of the
Company.  I further acknowledge that I
have been advised, as required by the Older Workers Benefit Protection Act,
that:  (a) the release and waiver granted
herein does not relate to claims under the ADEA which may arise after this
Release and Waiver is executed; (b) I have the right to consult with an attorney
prior to executing this Release and Waiver (although I may choose voluntarily
not to do so); and (c) I have twenty-one (21) days from the date of termination
of my employment with the Company in which to consider this Release and Waiver
(although I may choose voluntarily to execute this Release and Waiver earlier);
(d) I have seven (7) days following the execution of this Release and Waiver to
revoke

 1
 

my consent to this
Release and Waiver; and (e) this Release and Waiver shall not be effective
until the seven (7) day revocation period has expired.

I
acknowledge that I have the right to consult with an attorney prior to
executing this Release and Waiver (although I may choose voluntarily not to do
so); and (c) I have five (5) days from the date of termination of my employment
with the Company in which to consider this Release and Waiver (although I may
choose voluntarily to execute this Release and Waiver earlier).

I acknowledge my continuing
obligations under my Proprietary Information and Inventions Agreement, a copy
of which is attached to the Agreement as Exhibit B.  Pursuant to the Proprietary Information and
Inventions Agreement I understand that among other things, I must not use or
disclose any confidential or proprietary information of the Company and I must
immediately return all Company property and documents (including all
embodiments of proprietary information) and all copies thereof in my possession
or control.  I understand and agree that
my right to the severance pay I am receiving in exchange for my agreement to
the terms of this Release and Waiver is contingent upon my continued compliance
with my Proprietary Information & Inventions Agreement.

This Release and Waiver,
including Exhibit B to the Agreement, constitutes the complete, final and
exclusive embodiment of the entire agreement between the Company and me with
regard to the subject matter hereof.  I
am not relying on any promise or representation by the Company that is not
expressly stated herein.  This Release
and Waiver may only be modified by a writing signed by both me and a duly
authorized officer of the Company.

	
  Date: 

  	
   

  	
   

  	
   

  	
  By:

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
  Sharon Wicker

  

 

 2
 

EXHIBIT B

SENOMYX,
INC.

EMPLOYEE PROPRIETARY INFORMATION

AND INVENTIONS AGREEMENT

In
consideration of my employment or continued employment by SENOMYX, INC. (the “Company”), and
the compensation now and hereafter paid to me, I hereby agree as follows:

1.             NONDISCLOSURE

1.1            Recognition
of Company’s Rights; Nondisclosure. 
At all times during my employment and thereafter, I will hold in
strictest confidence and will not disclose, use, lecture upon or publish any of
the Company’s Proprietary Information (defined below), except as such
disclosure, use or publication may be required in connection with my work for
the Company, or unless an officer of the Company expressly authorizes such in
writing.  I will obtain Company’s written
approval before publishing or submitting for publication any material (written,
verbal, or otherwise) that relates to my work at Company and/or incorporates
any Proprietary Information.  I hereby
assign to the Company any rights I may have or acquire in such Proprietary
Information and recognize that all Proprietary Information shall be the sole
property of the Company and its assigns.

1.2            Proprietary
Information.  The term “Proprietary Information” shall mean any and all confidential
and/or proprietary knowledge, data or information of the Company.  By way of illustration but not limitation, “Proprietary Information” includes (a) trade secrets,
inventions, mask works, ideas, processes, formulas, source and object codes,
data, programs, other works of authorship, know-how, improvements, discoveries,
developments, designs and techniques (hereinafter collectively referred to as “Inventions”); and (b) information regarding plans for
research, development, new products, marketing and selling, business plans,
budgets and unpublished financial statements, licenses, prices and costs,
suppliers and customers; and (c) information regarding the skills and
compensation of other employees of the Company. 
Notwithstanding the foregoing, it is understood that, at all such times,
I am free to use information which is generally known in the trade or industry,
which is not gained as result of a breach of this Agreement, and my own, skill,
knowledge, know-how and experience to whatever extent and in whichever way I
wish.

1.3            Third
Party Information.  I understand, in
addition, that the Company has received and in the future will receive from
third parties confidential or proprietary information (“Third Party
Information”) subject to a duty on the Company’s part to maintain
the confidentiality of such information and to use it only for certain limited
purposes.  During the term of my
employment and thereafter, I will hold Third Party Information in the strictest
confidence and will not disclose to anyone (other than Company personnel who
need to know such information in connection with their work for the Company) or
use, except in connection with my work for the Company, Third Party Information
unless expressly authorized by an officer of the Company in writing.

1.4    No Improper Use of Information
of Prior Employers and Others. 
During my employment by the Company I will not improperly use or
disclose any confidential information or trade secrets, if any, of any former
employer or any other person to whom I have an obligation of confidentiality,
and I will not bring onto the premises of the Company any unpublished documents
or any property belonging to any former employer or any other person to whom I
have an obligation of confidentiality unless consented to in writing by that
former employer or person.  I will use in
the performance of my duties only information which is generally known and used
by persons with training and experience comparable to my own, which is common
knowledge in the industry or otherwise legally in the public domain, or which
is otherwise provided or developed by the Company.

2.             ASSIGNMENT OF INVENTIONS.

2.1            Proprietary
Rights.  The term “Proprietary Rights” shall mean all trade secret, patent,
copyright, mask work and other intellectual property rights throughout the
world.

2.2            Prior
Inventions.  Inventions, if any,
patented or unpatented, which I made prior to the commencement of my employment
with the Company are excluded from the scope of this Agreement.  To

 3
 

preclude
any possible uncertainty, I have set forth on Exhibit B
(Previous Inventions) attached hereto a complete list of all
Inventions that I have, alone or jointly with others, conceived, developed or
reduced to practice or caused to be conceived, developed or reduced to practice
prior to the commencement of my employment with the Company, that I consider to
be my property or the property of third parties and that I wish to have
excluded from the scope of this Agreement (collectively referred to as “Prior Inventions”). 
If disclosure of any such Prior Invention would cause me to violate any
prior confidentiality agreement, I understand that I am not to list such Prior
Inventions in Exhibit B but am only to
disclose a cursory name for each such invention, a listing of the party(ies) to
whom it belongs and the fact that full disclosure as to such inventions has not
been made for that reason. A space is provided on Exhibit B
for such purpose.  If no such disclosure
is attached, I represent that there are no Prior Inventions.  If, in the course of my employment with the
Company, I incorporate a Prior Invention into a Company product, process or
machine, the Company is hereby granted and shall have a nonexclusive,
royalty-free, irrevocable, perpetual, worldwide license (with rights to
sublicense through multiple tiers of sublicensees) to make, have made, modify,
use and sell such Prior Invention. 
Notwithstanding the foregoing, I agree that I will not incorporate, or
permit to be incorporated, Prior Inventions in any Company Inventions without
the Company’s prior written consent.

2.3            Assignment
of Inventions.  Subject to Sections
2.4, and 2.6, I hereby assign and agree to assign in the future (when any such
Inventions or Proprietary Rights are first reduced to practice or first fixed
in a tangible medium, as applicable) to the Company all my right, title and
interest in and to any and all Inventions (and all Proprietary Rights with
respect thereto) whether or not patentable or registrable under copyright or
similar statutes, made or conceived or reduced to practice or learned by me,
either alone or jointly with others, during the period of my employment with
the Company.  Inventions assigned to the
Company, or to a third party as directed by the Company pursuant to this
Section 2, are hereinafter referred to as “Company
Inventions.”

2.4            Nonassignable
Inventions.  This Agreement does not
apply to an Invention which qualifies fully as a nonassignable Invention under
Section 2870 of the California Labor Code (hereinafter “Section 2870”). 
I have reviewed the notification on Exhibit A
(Limited Exclusion Notification) and agree that my signature acknowledges
receipt of the notification.

2.5            Obligation
to Keep Company Informed.  During the
period of my employment and for six (6) months after termination of my
employment with the Company, I will promptly disclose to the Company fully and
in writing all Inventions authored, conceived or reduced to practice by me,
either alone or jointly with others.  In
addition, I will promptly disclose to the Company all patent applications filed
by me or on my behalf within a year after termination of employment.  At the time of each such disclosure, I will
advise the Company in writing of any Inventions that I believe fully qualify
for protection under Section 2870; and I will at that time provide to the
Company in writing all evidence necessary to substantiate that belief.  The Company will keep in confidence and will
not use for any purpose or disclose to third parties without my consent any
confidential information disclosed in writing to the Company pursuant to this
Agreement relating to Inventions that qualify fully for protection under the
provisions of Section 2870.  I will
preserve the confidentiality of any Invention that does not fully qualify for
protection under Section 2870.

2.6            Government
or Third Party.  I also agree to
assign all my right, title and interest in and to any particular Company
Invention to a third party, including without limitation the United States, as
directed by the Company.

2.7            Works
for Hire.  I acknowledge that all
original works of authorship which are made by me (solely or jointly with
others) within the scope of my employment and which are protectable by
copyright are “works made for hire,” pursuant to United States Copyright Act
(17 U.S.C., Section 101).

2.8            Enforcement
of Proprietary Rights.  I will assist
the Company in every proper way to obtain, and from time to time enforce,
United States and foreign Proprietary Rights relating to Company Inventions in
any and all countries.  To that end I
will execute, verify and deliver such documents and perform such other acts
(including appearances as a witness) as the Company may reasonably request for
use in applying for, obtaining, perfecting, evidencing, sustaining and
enforcing such Proprietary Rights and the assignment thereof.  In addition, I will execute, verify and
deliver assignments of such Proprietary Rights to the Company or its designee.  My obligation to assist the Company with
respect to Proprietary Rights relating to such Company Inventions in any and

 4
 

all
countries shall continue beyond the termination of my employment, but the
Company shall compensate me at a reasonable rate after my termination for the
time actually spent by me at the Company’s request on such assistance.

In the event the Company is unable for any reason,
after reasonable effort, to secure my signature on any document needed in
connection with the actions specified in the preceding paragraph, I hereby
irrevocably designate and appoint the Company and its duly authorized officers
and agents as my agent and attorney in fact, which appointment is coupled with
an interest, to act for and in my behalf to execute, verify and file any such
documents and to do all other lawfully permitted acts to further the purposes
of the preceding paragraph with the same legal force and effect as if executed
by me.  I hereby waive and quitclaim to
the Company any and all claims, of any nature whatsoever, which I now or may
hereafter have for infringement of any Proprietary Rights assigned hereunder to
the Company.

3.             RECORDS. 
I agree to keep and maintain adequate and current records (in the
form of notes, sketches, drawings and in any other form that may be required by
the Company) of all Proprietary Information developed by me and all Inventions
made by me during the period of my employment at the Company, which records
shall be available to and remain the sole property of the Company at all times.

4.             ADDITIONAL ACTIVITIES.  I agree that during the period of my
employment by the Company I will not, without the Company’s express written
consent, engage in any employment or business activity which is competitive
with, or would otherwise conflict with, my employment by the Company.  I agree further that for the period of my
employment by the Company and for one (l) year after the date of termination of
my employment by the Company I will not induce any employee of the Company to
leave the employ of the Company.

5.             NO CONFLICTING OBLIGATION.  I represent that my performance of all the
terms of this Agreement and as an employee of the Company does not and will not
breach any agreement to keep in confidence information acquired by me in
confidence or in trust prior to my employment by the Company.  I have not entered into, and I agree I will
not enter into, any agreement either written or oral in conflict herewith.

6.             RETURN OF COMPANY DOCUMENTS.  When I leave the employ of the Company, I
will deliver to the Company any and all drawings, notes, memoranda,
specifications, devices, formulas, and documents, together with all copies
thereof, and any other material containing or disclosing any Company
Inventions, Third Party Information or Proprietary Information of the Company.  I further agree that any property situated on
the Company’s premises and owned by the Company, including disks and other
storage media, filing cabinets or other work areas, is subject to inspection by
Company personnel at any time with or without notice.  Prior to leaving, I will cooperate with the
Company in completing and signing the Company’s termination statement.

7.             LEGAL AND EQUITABLE REMEDIES.  Because my services are personal and unique
and because I may have access to and become acquainted with the Proprietary
Information of the Company, the Company shall have the right to enforce this
Agreement and any of its provisions by injunction, specific performance or
other equitable relief, without bond and without prejudice to any other rights
and remedies that the Company may have for a breach of this Agreement.

8.             NOTICES.  Any notices required or permitted hereunder
shall be given to the appropriate party at the address specified below or at SUCH other address as the party shall specify in
writing.  Such notice shall be deemed
given upon personal delivery to the appropriate address or if sent by certified
or registered mail, three (3) days after the date of mailing.

9.             NOTIFICATION OF NEW EMPLOYER.  In the event that I leave the employ of the
Company, I hereby consent to the notification of my new employer of my rights
and obligations under this Agreement.

10.          GENERAL PROVISIONS.

10.1         Governing
Law; Consent to Personal Jurisdiction. 
This Agreement will be governed by and construed according to the laws
of the State of California, as such laws are applied to agreements entered into
and to be performed entirely within California between California
residents.  I hereby expressly consent to
the personal jurisdiction of the state and federal courts located in San Diego
County, California for any lawsuit filed there against me by Company arising
from or related to this Agreement.

10.2         Severability.  In case any one or more of the provisions
contained in this Agreement shall, for any reason, be held to be invalid,
illegal or

 5
 

unenforceable
in any respect, such invalidity, illegality or unenforceability shall not
affect the other provisions of this Agreement, and this Agreement shall be
construed as if such invalid, illegal or unenforceable provision had never been
contained herein.  If moreover, any one
or more of the provisions contained in this Agreement shall for any reason be
held to be excessively broad as to duration, geographical scope, activity or
subject, it shall be construed by limiting and reducing it, so as to be enforceable
to the extent compatible with the applicable law as it shall then appear.

10.3         Successors
and Assigns.  This Agreement will be
binding upon my heirs, executors, administrators and other legal
representatives and will be for the benefit of the Company, its successors, and
its assigns.

10.4         Survival.  The provisions of this Agreement shall
survive the termination of my employment and the assignment of this Agreement
by the Company to any successor in interest or other assignee.

10.5         Employment.  I agree and understand that nothing in this
Agreement shall confer any right with respect to continuation of employment by
the Company, nor shall it interfere in any way with my right or the Company’s
right to terminate my employment at any time, with or without cause.

10.6         Waiver.  No waiver by the Company of any breach of
this Agreement shall be a waiver of any preceding or succeeding breach.  No waiver by the Company of any right under
this Agreement shall be construed as a waiver of any other right.  The Company shall not be required to give
notice to enforce strict adherence to all terms of this Agreement.

10.7         Entire
Agreement.  The obligations pursuant
to Sections 1 and 2 of this Agreement shall apply to any time during which I
was previously employed, or am in the future employed, by the Company as a
consultant if no other agreement governs nondisclosure and assignment of
inventions during such period.  This
Agreement is the final, complete and exclusive agreement of the parties with
respect to the subject matter hereof and supersedes and merges all prior
discussions between us.  No modification
of or amendment to this Agreement, nor any waiver of any rights under this
Agreement, will be effective unless in writing and signed by the party to be
charged.  Any subsequent change or
changes in my duties, salary or compensation will not affect the validity or
scope of this Agreement.

This Agreement
shall be effective as of the first day of my employment with the Company,
namely:                 ,
20   .

I HAVE READ THIS AGREEMENT CAREFULLY AND UNDERSTAND ITS TERMS.  I HAVE COMPLETELY FILLED OUT EXHIBIT B
TO THIS AGREEMENT.

	
  Dated:

  	
   

  	
   

  
	
   

  
	
   

  	
   

  
	
  (Signature)

  
	
   

  
	
   

  	
   

  
	
  (Printed
  Name)

  
	
   

  
	
   

  
	
  Accepted and Agreed
  To:

  
	
   

  
	
  Senomyx, Inc.

  
	
   

  
	
   

  
	
  By:

  	
   

  	
   

  
	
   

  
	
  Title:

  	
   

  	
   

  
	
   

  
	
   

  	
   

  
	
  (Address)

  
	
   

  	
   

  
	
   

  
	
  Dated:

  	
   

  	
   

  
								

 

 6

EXHIBIT A

LIMITED EXCLUSION NOTIFICATION

THIS IS TO NOTIFY you in accordance with Section 2872
of the California Labor Code that the foregoing Agreement between you and the
Company does not require you to assign or offer to assign to the Company any
invention that you developed entirely on your own time without using the
Company’s equipment, supplies, facilities or trade secret information except
for those inventions that either:

1.                                                 Relate
at the time of conception or reduction to practice of the invention to the
Company’s business, or actual or demonstrably anticipated research or
development of the Company;

2.                Result
from any work performed by you for the Company.

To the extent a
provision in the foregoing Agreement purports to require you to assign an invention
otherwise excluded from the preceding paragraph, the provision is against the
public policy of this state and is unenforceable.

This limited
exclusion does not apply to any patent or invention covered by a contract
between the Company and the United States or any of its agencies requiring full
title to such patent or invention to be in the United States.

I ACKNOWLEDGE RECEIPT of a copy of this notification.

	
   

  	
  By:

  	
   

  	
   

  
	
   

  	
   

  	
  (Printed Name of Employee)

  
	
   

  	
   

  	
   

  
	
   

  	
  Date:

  	
   

  	
   

  
	
  Witnessed by:

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
  (Printed
  Name of Representative)

  	
   

  	
   

  
						

 

 1
 

EXHIBIT B

	
  TO:

  	
   

  	
  Senomyx, Inc.

  
	
   

  	
   

  	
   

  
	
  FROM:

  	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
  DATE:

  	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
  SUBJECT:

  	
   

  	
  Previous Inventions

  

 

1.             Except as listed in
Section 2 below, the following is a complete list of all inventions or
improvements relevant to the subject matter of my employment by SENOMYX, INC. (the “Company”) that have been made or conceived or first reduced
to practice by me alone or jointly with others prior to my engagement by the
Company:

	
  o

  	
  No inventions or improvements.

  
	
   

  	
   

  
	
  o

  	
  See below:

  
	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  
	
  o        Additional
  sheets attached.

  

 

2.             Due to a prior
confidentiality agreement, I cannot complete the disclosure under
Section 1 above with respect to inventions or improvements generally
listed below, the proprietary rights and duty of confidentiality with respect
to which I owe to the following party(ies):

	
  

  	
  Invention or Improvement

  	
   

  	
  Party(ies)

  	
   

  	
  Relationship

  
	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  1.

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  2.

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  3.

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
   

  	
   

  	
   

  
	
  o

  	
  Additional sheets attached.

  	
   

  	
   

  	
   

  	
   

  

 

 2

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00117-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00117-of-00352.parquet"}]]