Document:

exv4w17

 

EXHIBIT 4.17

AMENDMENT TO

WARRANT TO PURCHASE SERIES D PREFERRED STOCK

OF ARTES MEDICAL, INC.

(Issued in Connection with Interim Credit Facility 2005)

     This Amendment dated as of June 23, 2006 (this “Amendment”), to each of the Warrants to
Purchase Series D Preferred Stock (each, a “Warrant” and collectively, the “Warrants”) for the
purchase of shares of Series D Preferred Stock of Artes Medical,
Inc. (the “Company”), is made by
and between the Company and each of the holders of one or more Warrants listed on Exhibit A
(each, a “Holder” and collectively, the
“Holders”).

RECITALS

     Whereas, pursuant to the Preamble of each Warrant, each of the Warrants expires and
ceases to be exercisable on the earlier of (i) 5:00 P.M. Pacific Standard Time, on the date set
forth under “Original Expiration Date” on Exhibit A hereto or (ii) the closing of (a) a
Corporate Transaction (as defined in the Warrant) or (b) the initial underwritten public offering
of the Company’s common stock pursuant to a registration statement filed under the Securities Act
of 1933, as amended;

     Whereas, pursuant to Section 3 of each Warrant, each Holder is entitled to exercise
such Holder’s Warrant through a “cashless exercise” feature by converting the Warrant into Warrant
Shares (as defined in each of the Warrants) at any time or from time to time during the exercise
period, the number of Warrant Shares to be computed using the Net Issuance formula provided in
Section 3.1 of the Warrant; and

     Whereas, the Company and each of the Holders desire to amend the Warrants held by the
Holders as set forth below.

AGREEMENT

     NOW, THEREFORE, IT IS HEREBY AGREED AS FOLLOWS:

     1. Amendment to Preamble. The first paragraph of the Preamble of each of the Warrants
is hereby amended and restated in its entirety to read as follows:

     “Artes Medical USA, Inc., a Delaware corporation (the “Company”), hereby certifies that, for
value received, ___(including any successors and assigns, “Holder”), is entitled,
subject to the terms set forth below, to purchase from the Company at any time or from time to time
before the earlier of (i) 5:00 P.M. Pacific Standard Time, on the date set forth with respect to
this Warrant under “Original Expiration Date” on Exhibit A of this Amendment or (ii) the
closing of a Corporate Transaction (the earlier to occur of (i) or (ii) the “Expiration Date”),
fully paid and nonassessable shares of the Company’s Series D Preferred Stock (the “Warrant
Shares”) under the terms set forth herein:”

     2. Amendment to Section 3. Section 3 of each of the Warrants is hereby deleted in its
entirety.

 

 

     3. Governing Law. This Amendment shall be governed by and construed in accordance
with the laws of the State of California as applied to agreements among California residents,
entered into and to be performed entirely within California.

     4. Successors and Assigns. This Amendment shall be binding upon, and inure to the
benefit of, the parties hereto, their respective successors and legal representatives and their
permitted assigns.

     5. Warrant Terms to Remain in Effect. Except as specifically otherwise modified
herein, each Warrant as previously executed remains in full force and effect.

     6. Effectiveness; No Amendment to Other Warrants. This Amendment shall become
effective as to each of the Warrants upon the execution and delivery by each Holder of a Warrant
Holder Election Form in the form provided by the Company to the Holder with respect to the
applicable Warrant, indicating such Holder’s agreement to be bound by this Amendment.
Notwithstanding Section 8.5 of each Warrant, this Amendment shall be effective only as to each
Warrant that the applicable Holder has elected to amend as set forth in this Section 6, and shall
not be effective as to any other warrant. Each Warrant so amended by this Amendment shall be
listed on Exhibit A.

     7. Counterparts. This Amendment may be executed in any number of counterparts, each
of which shall be deemed an original, but all of which together shall constitute one and the same
instrument.

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]

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	Acknowledged and agreed:	 	ARTES MEDICAL, INC.,
	 	 	a Delaware corporation
	 
	 	 	 	 	 	 
	 

	 	By:	 	 	 	 
	 

	 	 	 	 

	 	 
	 

	 	Name:	 	 	 	 
	 

	 	 	 	 

	 	 
	 

	 	Title:	 	 	 	 
	 

	 	 	 	 

	 	 

[Signature Page to Amendment to Warrant to Purchase Series D Preferred Stock]

 

 

EXHIBIT A

WARRANT HOLDERS

	 	 	 	 	 	 	 	 	 	 	 	 	 
	 	 	Number of	 	 	 	 	 	 
	 	 	Shares	 	 	 	 	 	 
	 	 	Underlying	 	 	 	 	 	Original
	Name of Warrant Holder	 	Warrant	 	Exercise Price	 	Expiration Date
	Charles M. Ewell
	 	 	75,000	 	 	$	2.00	 	 	 	05/10/10	 
	IC-1, LLC
	 	 	145,500	 	 	$	2.00	 	 	 	05/13/10	 
	First Roseland Pension
& Profit Sharing Plan
	 	 	75,000	 	 	$	2.00	 	 	 	05/18/10Exhibit 4.18

 

EXHIBIT 4.18

THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES
ACT OF 1933, AS AMENDED (THE “ACT”), OR ANY APPLICABLE STATE SECURITIES LAWS, AND MAY NOT BE SOLD,
PLEDGED OR OTHERWISE TRANSFERRED WITHOUT AN EFFECTIVE REGISTRATION THEREOF UNDER THE ACT AND ANY
APPLICABLE STATE SECURITIES LAWS, OR PURSUANT TO RULE 144 OR AN EXEMPTION FROM THE REGISTRATION
REQUIREMENTS OF THE ACT AND ANY APPLICABLE STATE SECURITIES LAWS.

WARRANT TO PURCHASE STOCK

	 	 	 
	Corporation:

	 	ARTES MEDICAL, INC., a Delaware corporation
	Number of Shares:

	 	120,000 
	Class of Stock:

	 	Series E Preferred Stock
	Initial Exercise Price:

	 	$2.50 per share
	Issue Date:

	 	November 27, 2006 
	Expiration Date:

	 	November 27, 2016 (Subject to Section 1.5.2 and 5.1)

     THIS WARRANT TO PURCHASE STOCK (“WARRANT”) CERTIFIES THAT, for good and valuable
consideration, the receipt of which is hereby acknowledged, COMERICA BANK, a Michigan banking
corporation, or its assignee (“Holder”), is entitled to purchase the number of fully paid and
nonassessable shares of the class of securities (the “Shares”) of ARTES MEDICAL, INC. (the
“Company”) at the initial exercise price per Share (the “Warrant Price”) all as set forth above and
as adjusted pursuant to Article 2 of this Warrant, subject to the provisions and upon the terms
and conditions set forth in this Warrant.

ARTICLE 1. EXERCISE.

     1.1 Method of Exercise. Holder may exercise this Warrant by delivering this Warrant
and a duly executed Notice of Exercise in substantially the form attached as Appendix 1 to the
principal office of the Company. Holder shall also deliver to the Company a check or wire for the
aggregate Warrant Price for the Shares being purchased.

     1.2 Intentionally Omitted.

     1.3 Delivery of Certificate and New Warrant. Within 45 days after Holder exercises
this Warrant, the Company shall deliver to Holder certificates for the Shares acquired and, if this
Warrant has not been fully exercised and has not expired, a new warrant representing the Shares not
so acquired.

     1.4 Replacement of Warrants. In the case of loss, theft or destruction of this
Warrant, on delivery of an indemnity agreement reasonably satisfactory in form and amount to the
Company or, in the case of mutilation, on surrender and cancellation of this Warrant, the Company
at its expense shall execute and deliver, in lieu of this Warrant, a new warrant of like tenor.

     1.5 Acquisition of the Company.

          1.5.1 “Acquisition.” For the purpose of this Warrant, “Acquisition” means (a) any
sale, license, or other disposition of all or substantially all of the assets (including
intellectual property) of the Company, or (b) any reorganization, consolidation, merger or sale of
the voting securities of the Company or any other transaction where the holders of the Company’s
securities before the transaction beneficially own less than 50% of the outstanding voting
securities of the surviving entity after the transaction.

          1.5.2 Treatment of Warrant in the Event of an Acquisition. The Company shall give
Holder written notice at least 20 days prior to the closing of any proposed Acquisition. The
Company will use commercially reasonable efforts to cause the acquirer of the Company under the
Acquisition (the “Acquirer”) to assume this Warrant as a part of the Acquisition.

1

 

          (a) If the Acquirer assumes this Warrant, then this Warrant shall be exercisable for the same
securities, cash, and property as would be payable for the Shares issuable upon exercise of the
unexercised portion of this Warrant as if such Shares were outstanding on the record date for the
Acquisition and subsequent closing. The Warrant Price shall be adjusted accordingly, and the
Warrant Price and number and class of Shares shall continue to be subject to adjustment from time
to time in accordance with the provisions hereof.

          (b) If the Acquirer refuses to assume this Warrant in connection with the Acquisition, the
Company shall give Holder an additional written notice at least 5 days prior to the closing of the
Acquisition of such fact. In such event, notwithstanding any other provision of this Warrant to
the contrary, Holder may immediately exercise this Warrant in the manner specified in this Warrant
with such exercise effective immediately prior to closing of the Acquisition.

ARTICLE 2. ADJUSTMENTS TO THE SHARES.

     2.1 Stock Dividends, Splits, Etc. If the Company declares or pays a dividend on its
common stock payable in common stock, or other securities, or subdivides the outstanding common
stock into a greater amount of common stock, then upon exercise of this Warrant, for each Share
acquired, Holder shall receive, without cost to Holder, the total number and kind of securities to
which Holder would have been entitled had Holder owned the Shares of record as of the date the
dividend or subdivision occurred.

     2.2 Reclassification, Exchange or Substitution. Upon any reclassification, exchange,
substitution, or other event that results in a change of the number and/or class of the securities
issuable upon exercise or conversion of this Warrant, Holder shall be entitled to receive, upon
exercise or conversion of this Warrant, the number and kind of securities and property that Holder
would have received for the Shares if this Warrant had been exercised immediately before such
reclassification, exchange, substitution, or other event. Such an event shall include any
automatic conversion of the outstanding or issuable securities of the Company of the same class or
series as the Shares to common stock pursuant to the terms of the Company’s Certificate of
Incorporation upon the closing of a registered public offering of the Company’s common stock or
otherwise. The Company or its successor shall promptly issue to Holder a new warrant for such new
securities or other property. The new warrant shall provide for adjustments which shall be as
nearly equivalent as may be practicable to the adjustments provided for in this Article 2
including, without limitation, adjustments to the Warrant Price and to the number of securities or
property issuable upon exercise of the new warrant. The provisions of this Section 2.2 shall
similarly apply to successive reclassifications, exchanges, substitutions, or other events.

     2.3 Adjustments for Combinations, Etc. If the outstanding Shares are combined or
consolidated, by reclassification, reverse split or otherwise, into a lesser Number of Shares, the
Warrant Price shall be proportionately increased. If the outstanding Shares are split or
multiplied, by reclassification or otherwise, into a greater Number of Shares, the Warrant Price
shall be proportionately decreased.

     2.4 Adjustments for Diluting Issuances. The Warrant Price and the Number of Shares
issuable upon exercise of this Warrant shall be subject to adjustment, from time to time, in the
manner set forth on Exhibit A, if attached, in the event of Diluting Issuances (as defined on
Exhibit A).

     2.5 No Impairment. The Company shall not, by amendment of its Certificate of
Incorporation or through a reorganization, transfer of assets, consolidation, merger, dissolution,
issue, or sale of securities or any other voluntary action, avoid or seek to avoid the observance
or performance of any of the terms to be observed or performed under this Warrant by the Company,
but shall at all times in good faith assist in carrying out all the provisions of this Article 2
and in taking all such action as may be necessary or appropriate to protect Holder’s rights under
this Article 2 against impairment. Notwithstanding the foregoing, nothing in this Section 2.5
shall prevent the Company from treating Holder in the same manner as all other holders of the
Company’s Series E Preferred Stock.

     2.6 Certificate as to Adjustments. Upon each adjustment of the Warrant Price, the
Company at its expense shall promptly compute such adjustment, and furnish Holder with a
certificate signed by its Chief Financial Officer setting forth such adjustment and the facts upon
which such adjustment is based. The Company shall, upon

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written request, furnish Holder a certificate setting forth the Warrant Price in effect upon
the date thereof and the series of adjustments leading to such Warrant Price.

     2.7 Fractional Shares. No fractional Shares shall be issuable upon exercise of this
Warrant and the Number of Shares to be issued shall be rounded down to the nearest whole Share. If
a fractional share interest arises upon any exercise of the Warrant, the Company shall eliminate
such fractional share interest by paying Holder an amount computed by multiplying the fractional
interest by the fair market value, as determined by the Company’s Board of Directors, of a full
Share.

ARTICLE 3. REPRESENTATIONS AND COVENANTS OF THE COMPANY.

     3.1 Representations and Warranties. The Company hereby represents and warrants to,
and agrees with, the Holder as follows:

          3.1.1 The initial Warrant Price referenced on the first page of this Warrant is not greater
than the fair market value of the Shares as of the date of this Warrant.

          3.1.2 All Shares which may be issued upon the exercise of the purchase right represented by
this Warrant, and all securities, if any, issuable upon conversion of the Shares, shall, upon
issuance, be duly authorized, validly issued, fully paid and nonassessable, and free of any liens
and encumbrances except for restrictions on transfer provided for herein or under applicable
federal and state securities laws.

          3.1.3 The Company’s capitalization table attached to this Warrant is true and complete as of
the Issue Date.

     3.2 Notice of Certain Events. If the Company proposes at any time (a) to declare any
dividend or distribution upon its stock, whether in cash, property, stock, or other securities and
whether or not a regular cash dividend; (b) to offer for subscription pro rata to the holders of
any class or series of its stock any additional shares of stock of any class or series or other
rights; (c) to effect any reclassification or recapitalization of stock; or (d) to merge or
consolidate with or into any other corporation, or sell, lease, license, or convey all or
substantially all of its assets, or to liquidate, dissolve or wind up, then, in connection with
each such event, the Company shall give Holder (1) at least 20 days prior written notice of the
date on which a record will be taken for such dividend, distribution, or subscription rights (and
specifying the date on which the holders of stock will be entitled thereto) or for determining
rights to vote, if any, in respect of the matters referred to in (a) and (b) above; and (2) in the
case of the matters referred to in (c) and (d) above at least 20 days prior written notice of the
date when the same will take place (and specifying the date on which the holders of stock will be
entitled to exchange their stock for securities or other property deliverable upon the occurrence
of such event).

     3.3 Information Rights. So long as the Holder holds this Warrant and/or any of the
Shares, the Company shall deliver to the Holder (a) promptly after mailing, copies of all
communiqués to the stockholders of the Company, (b) within one hundred twenty (120) days after the
end of each fiscal year of the Company, the annual audited financial statements of the Company
certified by independent public accountants of recognized standing and (c) within forty-five (45)
days after the end of each of the first three quarters of each fiscal year, the Company’s
quarterly, unaudited financial statements.

     3.4 Registration Under Securities Act of 1933, as amended. The Company agrees that
the Shares or, if the Shares are convertible into common stock of the Company, such common stock,
shall be subject to the registration rights set forth on Exhibit B.

ARTICLE 4. INVESTMENT REPRESENTATIONS AND COVENANTS OF HOLDER.

     With respect to the acquisition of this Warrant and any of the Shares, Holder hereby
represents and warrants to, and agrees with, the Company as follows:

3

 

     4.1 Purchase Entirely for Own Account. This Warrant is issued to Holder in reliance
upon Holder’s representation to the Company that this Warrant and the Shares will be acquired for
investment for Holder’s, or its affiliate’s, own account, not as a nominee or agent, and not with a
view to the resale or distribution of any part thereof other than to an affiliate, and that Holder
has no present intention of selling, granting any participation in, or otherwise distributing the
same other than to an affiliate. By executing this Warrant, Holder further represents that Holder
does not have any contract, undertaking, agreement or arrangement with any person, other than an
affiliate, to sell, transfer or grant participations to such person or to any third person with
respect to any of the Shares.

     4.2 Reliance upon Holder’s Representations. Holder understands that this Warrant and
the Shares are not registered under the Act on the ground that the issuance of such securities is
exempt from registration under the Act, and that the Company’s reliance on such exemption is
predicated on Holder’s representations set forth herein.

     4.3 Accredited Investor Status. Holder represents to the Company that Holder is an
Accredited Investor (as defined in the Act).

     4.4 Restricted Securities. Holder understands that this Warrant and the Shares are
“restricted securities” under the federal securities laws inasmuch as they are being acquired from
the Company in a transaction not involving a public offering and that under such federal securities
laws and applicable regulations such securities may be resold without registration under the
Securities Act only in certain limited circumstances.

     4.5 Market Stand-Off. In connection with the initial public offering of the Company’s
securities and upon request of the Company or the underwriters managing such offering of the
Company’s securities, Holder shall not sell, make any short sale of, loan, grant any option for the
purchase of, or otherwise dispose of any securities of the Company, however or whenever acquired
(other than those included in the registration) without the prior written consent of the Company or
such underwriters, as the case may be, for such period of time (not to exceed 180 days, but subject
to such extension or extensions as may be required by the underwriters in order to publish research
reports while complying with the Rule 2711 of the National Association of Securities Dealers, Inc.)
from the effective date of such registration as may be requested by the Company or such managing
underwriters, and shall execute an agreement reflecting the foregoing as may be requested by the
underwriters at the time of the Company’s initial public offering; provided, that all officers and
directors of the Company and all greater than 5% stockholders enter into similar agreements; and
provided, further, that such market stand-off restriction shall not apply to a registration
relating solely to employee benefit plans, or to a registration relating solely to a transaction
pursuant to Rule 145 under the Securities Act. In order to enforce the foregoing covenants, the
Company may impose stop-transfer instructions with respect to the securities of Holder.

     ARTICLE 5. MISCELLANEOUS.

     5.1 Term; Exercise Upon Expiration. This Warrant is exercisable in whole or in part,
at any time and from time to time on or before the Expiration Date set forth above; provided,
however, that if the Company completes its initial public offering within the three-year period
immediately prior to the Expiration Date, the Expiration Date shall automatically be extended until
the third anniversary of the effective date of the Company’s initial public offering. The Company
shall give Holder written notice of Holder’s right to exercise this Warrant not less than 90 days
before the Expiration Date. If the notice is not so given, the Expiration Date shall automatically
be extended until 90 days after the date the Company delivers such notice to Holder.

     5.2 Legends. This Warrant and the Shares (and the securities issuable, directly or
indirectly, upon conversion of the Shares, if any) shall be imprinted with a legend in
substantially the following form:

          THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE
“ACT”), OR ANY APPLICABLE STATE SECURITIES LAWS, AND MAY NOT BE SOLD, PLEDGED OR OTHERWISE
TRANSFERRED WITHOUT AN EFFECTIVE REGISTRATION THEREOF UNDER THE ACT AND ANY APPLICABLE STATE
SECURITIES LAWS, OR PURSUANT TO RULE 144 OR AN EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE
ACT AND ANY APPLICABLE STATE SECURITIES LAWS.

4

 

     5.3 Compliance with Securities Laws on Transfer. This Warrant and the Shares issuable
upon exercise of this Warrant (and the securities issuable, directly or indirectly, upon conversion
of the Shares, if any) may not be transferred or assigned in whole or in part without compliance
with applicable federal and state securities laws by the transferor and the transferee.

     5.4 Transfer Procedure. Subject to the provisions of Section 5.3, Holder may transfer
all or part of this Warrant or the Shares issuable upon exercise of this Warrant (or the securities
issuable, directly or indirectly, upon conversion of the Shares, if any) by giving the Company
notice of the portion of this Warrant being transferred setting forth the name, address and
taxpayer identification number of the transferee and surrendering this Warrant to the Company for
reissuance to the transferee(s) (and Holder, if applicable); provided, however, that Holder may
transfer all or part of this Warrant to its affiliates, including, without limitation, Comerica
Incorporated, at any time without notice or the delivery of any other instrument to the Company,
and such affiliate shall then be entitled to all the rights of Holder under this Warrant and any
related agreements, and the Company shall cooperate fully in ensuring that any stock issued upon
exercise of this Warrant is issued in the name of the affiliate that exercises this Warrant. The
terms and conditions of this Warrant shall inure to the benefit of, and be binding upon, the
Company and the holders hereof and their respective permitted successors and assigns. Unless the
Company is filing financial information with the SEC pursuant to the Securities Exchange Act of
1934, the Company shall have the right to refuse to transfer any portion of this Warrant to any
person who directly competes with the Company.

     5.5 Notices. All notices and other communications from the Company to the Holder, or
vice versa, shall be deemed delivered and effective when given personally or mailed by first-class
registered or certified mail, postage prepaid, at such address as may have been furnished to the
Company or the Holder, as the case may be, in writing by the Company or such Holder from time to
time. All notices to the Holder shall be addressed as follows:

Comerica Bank c/o Comerica Incorporated

Attn: Warrant Administrator

500 Woodward Avenue, 32nd Floor, MC 3379

Detroit, MI 48226

     All notices to the Company shall be addressed as follows:

ARTES MEDICAL, INC.

5870 Pacific Center Boulevard

San Diego, CA 92121

     5.6 Amendments. This Warrant and any term hereof may be changed, waived, discharged
or terminated only by an instrument in writing signed by the party against which enforcement of
such change, waiver, discharge or termination is sought.

     5.7 Attorneys’ Fees. In the event of any dispute between the parties concerning the
terms and provisions of this Warrant, the party prevailing in such dispute shall be entitled to
collect from the other party all costs incurred in such dispute, including reasonable attorneys’
fees.

     5.8 Governing Law. This Warrant shall be governed by and construed in accordance with
the laws of the State of California, without giving effect to its principles regarding conflicts of
law.

     5.9 Confidentiality. The Company hereby agrees to keep the terms and conditions of
this Warrant confidential. Notwithstanding the foregoing confidentiality obligation, the Company
may disclose information relating to this Warrant as required by law, rule, regulation, court order
or other legal authority, provided that (i) the

5

 

Company has given Holder at least ten (10) days’ notice of such required disclosure, and (ii) the
Company only discloses information that is required, in the opinion of counsel reasonably
satisfactory to Holder, to be disclosed.

	 	 	 	 	 
	 	 	ARTES MEDICAL, INC.
	 
	 	 	 	 
	 

	 	By:	 	/s/ Diane S. Goostree 
	 

	 	 	 	 
	 

	 	Name:	 	Diane S. Goostree 
	 

	 	 	 	 
	 

	 	Title:	 	Chief Executive Officer 
	 

	 	 	 	 
	 
	 	 	 	 
	 

	 	By:	 	/s/ Peter C. Wulff 
	 

	 	 	 	 
	 

	 	Name:	 	Peter C. Wulff 
	 

	 	 	 	 
	 

	 	Title:	 	Chief Financial Officer 
	 

	 	 	 	 

6

 

APPENDIX 1

NOTICE OF EXERCISE

     1. The undersigned hereby elects to purchase ___shares of the ___stock
of ARTES MEDICAL, INC. pursuant to the terms of the attached Warrant, and tenders herewith payment
of the purchase price of such shares in full.

     2. Please issue a certificate or certificates representing said shares in the name of the
undersigned or in such other name as is specified below:

Comerica Bank

Attn: Warrant Administrator

500 Woodward Avenue, 32nd Floor, MC 3379

Detroit, MI 48226

     3. The undersigned represents it is acquiring the shares solely for its own account and not as
a nominee for any other party and not with a view toward the resale or distribution thereof except
in compliance with applicable securities laws.

	 	 	 
	COMERICA BANK or Assignee
	 	 
	 
	 	 
	 

	 	 
	 

(Signature)

	 	 
	 
	 	 
	 
	 	 
	 

(Name and Title)

	 	 
	 
	 	 
	 
	 	 
	 

(Date)

	 	 

Appendix — 1

 

 

EXHIBIT A

Anti-Dilution Provisions

     In the event of the issuance of Additional Stock (as defined in the Company’s Fifth Amended
and Restated Certificate of Incorporation, as amended) by the Company, after the Issue Date of this
Warrant, of securities at a price per share less than the Warrant Price (a “Diluting Issuance”),
then the number of shares of common stock issuable upon conversion of the Shares shall be adjusted
in accordance with those provisions (the “Provisions”) of the Company’s Articles or Certificate of
Incorporation which apply to Diluting Issuances. The Provisions shall not be deemed in any manner
to limit or restrict the applicability of the Provisions to the Shares. Any language in the
Provisions that in any manner limits or restricts the applicability of the Provisions to the Shares
shall not apply to this Warrant.

     Under no circumstances shall the aggregate Warrant Price payable by the Holder upon exercise
of the Warrant increase as a result of any adjustment arising from a Diluting Issuance.

A-1

 

EXHIBIT B

Registration Rights

     The Shares (if common stock), or the common stock issuable upon conversion of the Shares,
shall be deemed “registrable securities” or otherwise entitled to “piggy back” registration rights
in accordance with the terms of the following agreement (the “Agreement”) between the Company and
its investor(s):

Amended and Restated Investors’ Rights Agreement dated June 23, 2006

     The Company agrees that no amendments will be made to the Agreement which would have an
adverse impact on Holder’s registration rights thereunder, in a manner that affects Holder
differently from other holders of Series E Preferred Stock, without the consent of Holder. By
acceptance of the Warrant to which this Exhibit B is attached, Holder shall be deemed to be a party
to the Agreement solely for the purpose of the above-mentioned registration rights.

B-1

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