Document:

Exhibit 4.1

 

DANIELS CORPORATE ADVISORY COMPANY, INC.

EMPLOYEES, OFFICERS, DIRECTORS, AND CONSULTANTS
STOCK PLAN

FOR THE YEAR 2014

 

1.Introduction.
This Plan shall be known as the “Daniels Corporate Advisory Company, Inc. Employees, Officers, Directors, and Consultants
Stock Plan for the Year 2015, No. 2” and is hereinafter referred to as the “Plan.” The purposes of this Plan
are to enable Daniels Corporate Advisory Company, Inc., a Nevada corporation (the “Company”), to promote the interests
of the Company and its stockholders by attracting and retaining Employees, Directors, and Consultants capable of furthering the
future success of the Company and by aligning their economic interests more closely with those of the Company’s stockholders,
by paying their retainer or fees in the form of shares of the Company’s common stock, par value $0.001 per share (the “Common
Stock”).

2.Definitions.
The following terms shall have the meanings set forth below:

“Board”
means the Board of Directors of the Company.

“Change of Control”
has the meaning set forth in Paragraph 12(d) hereof.

“Code”
means the Internal Revenue Code of 1986, as amended, and the rules and regulations thereunder. References to any provision of the
Code or rule or regulation thereunder shall be deemed to include any amended or successor provision, rule or regulation.

“Committee”
means the committee that administers this Plan, as more fully defined in Paragraph 13 hereof.

“Common Stock”
has the meaning set forth in Paragraph 1 hereof.

“Company”
has the meaning set forth in Paragraph 1 hereof.

“Consultants”
means the Company’s consultants and advisors only if: (i) they are natural persons; (ii) they provide bona fide services
to the Company; and (iii) the services are not in connection with the offer or sale of securities in a capital-raising transaction,
and do not directly or indirectly promote or maintain a market for the Company’s securities.

“Deferral Election”
has the meaning set forth in Paragraph 6 hereof.

“Deferred Stock
Account” means a bookkeeping account maintained by the Company for a Participant representing the Participant’s interest
in the shares credited to such Deferred Stock Account pursuant to Paragraph 7 hereof.

“Delivery Date”
has the meaning set forth in Paragraph 6 hereof.

“Director”
means an individual who is a member of the Board of Directors of the Company.

“Dividend Equivalent”
for a given dividend or other distribution means a number of shares of the Common Stock having a Fair Market Value, as of the record
date for such dividend or distribution, equal to the amount of cash, plus the Fair Market Value on the date of distribution of
any property, that is distributed with respect to one share of the Common Stock pursuant to such dividend or distribution; such
Fair Market Value to be determined by the Committee in good faith.

“Effective Date”
has the meaning set forth in Paragraph 3 hereof.

“Employee”
means any officer or employee of the Company.

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  “Exchange
Act” has the meaning set forth in Paragraph 12(d) hereof.

“Fair Market
Value” means the mean between the highest and lowest reported sales prices of the Common Stock on the New York Stock Exchange
Composite Tape or, if not listed on such exchange, on any other national securities exchange on which the Common Stock is listed
or on The Nasdaq Stock Market, or, if not so listed on any other national securities exchange or The Nasdaq Stock Market, then
the average of the bid price of the Common Stock during the last five trading days on the OTC Bulletin Board or the OTC Markets
Group Inc. immediately preceding the last trading day prior to the date with respect to which the Fair Market Value is to be determined.
If the Common Stock is not then publicly traded, then the Fair Market Value of the Common Stock shall be the book value of the
Company per share as determined on the last day of March, June, September, or December in any year closest to the date when the
determination is to be made. For the purpose of determining book value hereunder, book value shall be determined by adding as of
the applicable date called for herein the capital, surplus, and undivided profits of the Company, and after having deducted any
reserves theretofore established; the sum of these items shall be divided by the number of shares of the Common Stock outstanding
as of said date, and the quotient thus obtained shall represent the book value of each share of the Common Stock of the Company.

“Participant”
has the meaning set forth in Paragraph 4 hereof.

“Payment Time”
means the time when a Stock Award is payable to a Participant pursuant to Paragraph 5 hereof (without regard to the effect of any
Deferral Election).

“Stock Award”
has the meaning set forth in Paragraph 5 hereof.

“Third Anniversary”
has the meaning set forth in Paragraph 6 hereof.

3.Effective
Date of the Plan. This Plan was adopted by the Board effective March 9, 2015 (the “Effective Date”).

4.Eligibility.
Each individual who is an Employee, Director, or Consultant on the Effective Date and each individual who becomes an Employee,
Director, or Consultant thereafter during the term of this Plan shall be a participant (the “Participant”) in this
Plan, in each case during such period as such individual remains an Employee, Director, or Consultant of the Company or any of
its subsidiaries. Each credit of shares of the Common Stock pursuant to this Plan shall be evidenced by a written agreement duly
executed and delivered by or on behalf of the Company and a Participant, if such an agreement is required by the Company to assure
compliance with all applicable laws and regulations.

5.Grants of
Shares. Commencing on the Effective Date, the amount of compensation or bonus for service to the Participants shall be payable
in shares of the Common Stock (the “Stock Award”) pursuant to this Plan. The deemed issuance price of shares of the
Common Stock subject to each Stock Award shall not be less than 85 percent of the Fair Market Value of the Common Stock on the
date of the grant. In the case of any person who owns securities possessing more than ten percent of the combined voting power
of all classes of securities of the issuer or its parent or subsidiaries possessing voting power, the deemed issuance price of
shares of the Common Stock subject to each Stock Award shall be at least 100 percent of the Fair Market Value of the Common Stock
on the date of the grant.

6.Deferral
Option. From and after the Effective Date, a Participant may make an election (a “Deferral Election”) on an annual
basis to defer delivery of the Stock Award specifying which one of the following ways the Stock Award is to be delivered (a) on
the date which is three years after the Effective Date for which it was originally payable (the “Third Anniversary”),
(b) on the date upon which the Participant ceases to be a Participant for any reason (the “Departure Date”) or (c)
in five equal annual installments commencing on the Departure Date (the “Third Anniversary” and “Departure Date”
each being referred to herein as a “Delivery Date”). Such Deferral Election shall remain in effect for each Subsequent
Year unless changed, provided that, any Deferral Election with respect to a particular Year may not be changed less than six months
prior to the beginning of such Year, and provided, further, that no more than one Deferral Election or change thereof may be made
in any Year.

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 Any Deferral
Election and any change or revocation thereof shall be made by delivering written notice thereof to the Committee no later than
six months prior to the beginning of the Year in which it is to be effected; provided that, with respect to the Year beginning
on the Effective Date, any Deferral Election or revocation thereof must be delivered no later than the close of business on the
30th day after the Effective Date.

7.Deferred Stock
Accounts. The Company shall maintain a Deferred Stock Account for each Participant who makes a Deferral Election to which shall
be credited, as of the applicable Payment Time, the number of shares of the Common Stock payable pursuant to the Stock Award to
which the Deferral Election relates. So long as any amounts in such Deferred Stock Account have not been delivered to the Participant
under Paragraph 8 hereof, each Deferred Stock Account shall be credited as of the payment date for any dividend paid or other distribution
made with respect to the Common Stock, with a number of shares of the Common Stock equal to (a) the number of shares of the Common
Stock shown in such Deferred Stock Account on the record date for such dividend or distribution multiplied by (b) the Dividend
Equivalent for such dividend or distribution.

8.Delivery of
Shares.

(a)The shares
of the Common Stock in a Participant’s Deferred Stock Account with respect to any Stock Award for which a Deferral Election
has been made (together with dividends attributable to such shares credited to such Deferred Stock Account) shall be delivered
in accordance with this Paragraph 8 as soon as practicable after the applicable Delivery Date. Except with respect to a Deferral
Election pursuant to Paragraph 6 hereof, or other agreement between the parties, such shares shall be delivered at one time; provided
that, if the number of shares so delivered includes a fractional share, such number shall be rounded to the nearest whole number
of shares. If the Participant has in effect a Deferral Election pursuant to Paragraph 6 hereof, then such shares shall be delivered
in five equal annual installments (together with dividends attributable to such shares credited to such Deferred Stock Account),
with the first such installment being delivered on the first anniversary of the Delivery Date; provided that, if in order to equalize
such installments, fractional shares would have to be delivered, such installments shall be adjusted by rounding to the nearest
whole share. If any such shares are to be delivered after the Participant has died or become legally incompetent, they shall be
delivered to the Participant’s estate or legal guardian, as the case may be, in accordance with the foregoing; provided that,
if the Participant dies with a Deferral Election pursuant to Paragraph 6 hereof in effect, the Committee shall deliver all remaining
undelivered shares to the Participant’s estate immediately. References to a Participant in this Plan shall be deemed to refer
to the Participant’s estate or legal guardian, where appropriate.

(b)The Company
may, but shall not be required to, create a grantor trust or utilize an existing grantor trust (in either case, the “Trust”)
to assist it in accumulating the shares of the Common Stock needed to fulfill its obligations under this Paragraph 8. However,
Participants shall have no beneficial or other interest in the Trust and the assets thereof, and their rights under this Plan shall
be as general creditors of the Company, unaffected by the existence or nonexistence of the Trust, except that deliveries of Stock
Awards to Participants from the Trust shall, to the extent thereof, be treated as satisfying the Company’s obligations under
this Paragraph 8.

9.Share Certificates;
Voting and Other Rights. The certificates for shares delivered to a Participant pursuant to Paragraph 8 above shall be issued
in the name of the Participant, and from and after the date of such issuance the Participant shall be entitled to all rights of
a stockholder with respect to the Common Stock for all such shares issued in his name, including the right to vote the shares,
and the Participant shall receive all dividends and other distributions paid or made with respect thereto.

10.General Restrictions.

(a)Notwithstanding
any other provision of this Plan or agreements made pursuant thereto, the Company shall not be required to issue or deliver any
certificate or certificates for shares of the Common Stock under this Plan prior to fulfillment of all of the following conditions:

(i)Listing
or approval for listing upon official notice of issuance of such shares on the New York Stock Exchange, Inc., or such other securities
exchange as may at the time be a market for the Common Stock;

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 (ii)Any
registration or other qualification of such shares under any state or federal law or regulation, or the maintaining in effect
of any such registration or other qualification which the Committee shall, upon the advice of counsel, deem necessary or advisable;
and

(iii)Obtaining
any other consent, approval, or permit from any state or federal governmental agency which the Committee shall, after receiving
the advice of counsel, determine to be necessary or advisable.

(b)Nothing
contained in this Plan shall prevent the Company from adopting other or additional compensation arrangements for the Participants.

11.Shares Available.
Subject to Paragraph 12 below, the maximum number of shares of the Common Stock which may in the aggregate be paid as Stock Awards
pursuant to this Plan is 2,500,000. Shares of the Common Stock issuable under this Plan may be taken from treasury shares of the
Company or purchased on the open market.

12.Adjustments;
Change of Control.

(a)In the event
that there is, at any time after the Board adopts this Plan, any change in corporate capitalization, such as a stock split, combination
of shares, exchange of shares, warrants or rights offering to purchase the Common Stock at a price below its Fair Market Value,
reclassification, or recapitalization, or a corporate transaction, such as any merger, consolidation, separation, including a spin-off,
stock dividend, or other extraordinary distribution of stock or property of the Company, any reorganization (whether or not such
reorganization comes within the definition of such term in Section 368 of the Code) or any partial or complete liquidation of the
Company (each of the foregoing a “Transaction”), in each case other than any such Transaction which constitutes a Change
of Control (as defined below), (i) the Deferred Stock Accounts shall be credited with the amount and kind of shares or other property
which would have been received by a holder of the number of shares of the Common Stock held in such Deferred Stock Account had
such shares of the Common Stock been outstanding as of the effectiveness of any such Transaction, (ii) the number and kind of shares
or other property subject to this Plan shall likewise be appropriately adjusted to reflect the effectiveness of any such Transaction,
and (iii) the Committee shall appropriately adjust any other relevant provisions of this Plan and any such modification by the
Committee shall be binding and conclusive on all persons.

(b)If the shares
of the Common Stock credited to the Deferred Stock Accounts are converted pursuant to Paragraph 12(a) into another form of property,
references in this Plan to the Common Stock shall be deemed, where appropriate, to refer to such other form of property, with such
other modifications as may be required for this Plan to operate in accordance with its purposes. Without limiting the generality
of the foregoing, references to delivery of certificates for shares of the Common Stock shall be deemed to refer to delivery of
cash and the incidents of ownership of any other property held in the Deferred Stock Accounts.

(c)In lieu
of the adjustment contemplated by Paragraph 12(a), in the event of a Change of Control, the following shall occur on the date of
the Change of Control (i) the shares of the Common Stock held in each Participant’s Deferred Stock Account shall be deemed
to be issued and outstanding as of the Change of Control; (ii) the Company shall forthwith deliver to each Participant who has
a Deferred Stock Account all of the shares of the Common Stock or any other property held in such Participant’s Deferred
Stock Account; and (iii) this Plan shall be terminated.

(d)For purposes
of this Plan, Change of Control shall mean any of the following events:

(i)The acquisition
by any individual, entity or group (within the meaning of Section 13(d)(3) or 14(d)(2) of the Securities Exchange Act of 1934,
as amended (the “Exchange Act”)) (a “Person”) of beneficial ownership (within the meaning of Rule 13d-3
promulgated under the Exchange Act) of 80 percent or more of either (1) the then outstanding shares of the Common Stock of the
Company (the “Outstanding Company Common Stock”), or (2) the combined voting power of then outstanding voting securities
of the Company entitled to vote generally in the election of directors (the “Outstanding Company Voting Securities”);
provided,

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however, that the following acquisitions shall not constitute a Change of Control (A) any acquisition directly from the
Company (excluding an acquisition by virtue of the exercise of a conversion privilege unless the security being so converted was
itself acquired directly from the Company), (B) any acquisition by the Company, (C) any acquisition by any employee benefit plan
(or related trust) sponsored or maintained by the Company or any corporation controlled by the Company or (D) any acquisition by
any corporation pursuant to a reorganization, merger or consolidation, if, following such reorganization, merger or consolidation,
the conditions described in clauses (A), (B) and (C) of paragraph (iii) of this Paragraph 12(d) are satisfied; or

(ii)Individuals
who, as of the date hereof, constitute the Board of the Company (as of the date hereof, “Incumbent Board”) cease for
any reason to constitute at least a majority of the Board; provided, however, that any individual becoming a director subsequent
to the date hereof whose election, or nomination for election by the Company’s stockholders, was approved by a vote of at
least a majority of the directors then comprising the Incumbent Board shall be considered as though such individual were a member
of the Incumbent Board, but excluding, for this purpose, any such individual whose initial assumption of office occurs as a result
of either an actual or threatened election contest (as such terms are used in Rule 14a-11 of Regulation 14A promulgated under the
Exchange Act) or other actual or threatened solicitation of proxies or consents by or on behalf of a Person other than the Board;
or

(iii)Approval
by the stockholders of the Company of a reorganization, merger, binding share exchange or consolidation, unless, following such
reorganization, merger, binding share exchange or consolidation (A) more than 60 percent of, respectively, then outstanding shares
of common stock of the corporation resulting from such reorganization, merger, binding share exchange or consolidation and the
combined voting power of then outstanding voting securities of such corporation entitled to vote generally in the election of directors
is then beneficially owned, directly or indirectly, by all or substantially all of the individuals and entities who were the beneficial
owners, respectively, of the Outstanding Company Common Stock and Outstanding Company Voting Securities immediately prior to such
reorganization, merger, binding share exchange or consolidation in substantially the same proportions as their ownership, immediately
prior to such reorganization, merger, binding share exchange or consolidation, of the Outstanding Company Common Stock and Outstanding
Company Voting Securities, as the case may be, (B) no Person (excluding the Company, any employee benefit plan (or related trust)
of the Company or such corporation resulting from such reorganization, merger, binding share exchange or consolidation and any
Person beneficially owning, immediately prior to such reorganization, merger, binding share exchange or consolidation, directly
or indirectly, 20 percent or more of the Outstanding Company Common Stock or Outstanding Company Voting Securities, as the case
may be) beneficially owns, directly or indirectly, 20 percent or more of, respectively, then outstanding shares of common stock
of the corporation resulting from such reorganization, merger, binding share exchange or consolidation or the combined voting power
of then outstanding voting securities of such corporation entitled to vote generally in the election of directors, and (C) at least
a majority of the members of the board of directors of the corporation resulting from such reorganization, merger, binding share
exchange or consolidation were members of the Incumbent Board at the time of the execution of the initial agreement providing for
such reorganization, merger, binding share exchange or consolidation; or

(iv)Approval
by the stockholders of the Company of (1) a complete liquidation or dissolution of the Company, or (2) the sale or other disposition
of all or substantially all of the assets of the Company, other than to a corporation, with respect to which following such sale
or other disposition, (A) more than 60 percent of, respectively, then outstanding shares of common stock of such corporation and
the combined voting power of then outstanding voting securities of such corporation entitled to vote generally in the election
of directors is then beneficially owned, directly or indirectly, by all or substantially all of the individuals and entities who
were the beneficial owners, respectively, of the Outstanding Company Common Stock and Outstanding Company Voting Securities immediately
prior to such sale or other disposition in substantially the same proportion as their ownership, immediately prior to such sale
or other disposition, of the Outstanding Company Common Stock and Outstanding Company Voting Securities, as the case may be, (B)
no Person (excluding the Company and any employee benefit plan (or related trust) of the Company or such corporation and any Person
beneficially owning, immediately prior to such sale or other disposition, directly or indirectly, 20 percent or more of the Outstanding
Company Common Stock or Outstanding Company Voting Securities, as the case may be) beneficially owns, directly or indirectly,
20 percent or more of, respectively, then outstanding shares of common stock of such corporation and the combined voting power
of then outstanding voting securities of such corporation entitled to vote generally in the election of directors, and (C) at
least a majority of the members of the board of directors of such corporation were members of the

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Incumbent Board at the time of the
execution of the initial agreement or action of the Board providing for such sale or other disposition of assets of the Company.

13.Administration;
Amendment and Termination.

(a)The Plan
shall be administered by the Compensation Committee (the “Committee”) of, or appointed by, the Board of Directors of
the Company (the “Board”). The Committee shall select one of its members as Chairman and shall act by vote of a majority
of a quorum, or by unanimous written consent. A majority of its members shall constitute a quorum. The Committee shall be governed
by the provisions of the Company’s Bylaws and of Nevada law applicable to the Board, except as otherwise provided herein
or determined by the Board. The Committee shall have full and complete authority, in its discretion, but subject to the express
provisions of this Plan to administer all aspects of the Plan. All interpretations and constructions of this Plan by the Committee,
and all of its actions hereunder, shall be binding and conclusive on all persons for all purposes.

(b)The Board
may from time to time make such amendments to this Plan, including to preserve or come within any exemption from liability under
Section 16(b) of the Exchange Act, as it may deem proper and in the best interest of the Company without further approval of the
Company’s stockholders, provided that, to the extent required under Nevada law or to qualify transactions under this Plan
for exemption under Rule 16b-3 promulgated under the Exchange Act, no amendment to this Plan shall be adopted without further approval
of the Company’s stockholders and, provided, further, that if and to the extent required for this Plan to comply with Rule
16b-3 promulgated under the Exchange Act, no amendment to this Plan shall be made more than once in any six month period that would
change the amount, price or timing of the grants of the Common Stock hereunder other than to comport with changes in the Code,
the Employee Retirement Income Security Act of 1974, as amended, or the regulations thereunder. The Board may terminate this Plan
at any time by a vote of a majority of the members thereof.

14.Term of Plan.
No shares of the Common Stock shall be issued, unless and until the Directors of the Company have approved this Plan and all other
legal requirements have been met. This Plan was adopted by the Board effective March 9, 2015, and shall expire on March 9, 2025.

15.Governing
Law. This Plan and all actions taken thereunder shall be governed by, and construed in accordance with, the laws of the State
of Nevada.

16.Information
to Shareholders. The Company shall furnish to each of its stockholders financial statements of the Company at least annually.

17.Miscellaneous.

(a)Nothing
in this Plan shall be deemed to create any obligation on the part of the Board to nominate any Director for reelection by the Company’s
stockholders or to limit the rights of the stockholders to remove any Director.

(b)The Company
shall have the right to require, prior to the issuance or delivery of any shares of the Common Stock pursuant to this Plan, that
a Participant make arrangements satisfactory to the Committee for the withholding of any taxes required by law to be withheld
with respect to the issuance or delivery of such shares, including, without limitation, by the withholding of shares that would
otherwise be so issued or delivered, by withholding from any other payment due to the Participant, or by a cash payment to the
Company by the Participant. 

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IN WITNESS WHEREOF,
this Plan has been executed effective as of March 9, 2015.

	 	DANIELS CORPORATE ADVISORY COMPANY, INC.
	 	 
	By	/s/ Arthur D. Viola
	 	Arthur D. Viola, Chief Executive Officer
	 	 

 

    	7[*] = Certain confidential information contained in this document, marked by brackets, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended.

 

Exhibit 10.71

 

AMENDMENT N°2

TO THE LOAN AGREEMENT

entered into as of December 30, 2010

 

BETWEEN:

XOMA (US) LLC, a Delaware limited liability company having a place of business at 2910 Seventh Street, Berkeley, California 94710 ("XOMA”), on the one hand,

AND:

Les Laboratoires Servier, a corporation organized and existing under the laws of France, having offices at 50 rue Carnot, 92284 Suresnes, France, and Institut de Recherches Servier, a corporation organized and existing under the laws of France having offices at 3, rue de la République, 92150 Suresnes (these two entities jointly referred to as “SERVIER”), on the other hand,

XOMA and SERVIER are referred to herein individually as a “Party” and collectively as the “Parties”.

WHEREAS, SERVIER and XOMA are parties to an Amended and Restated Collaboration Agreement entered into as of February 14, 2012, and amended by an Amendment N°1 thereto dated as of November 4, 2014 (as such may be further amended by the parties thereto, the “Collaboration Agreement”) pursuant to which, among other things, XOMA and SERVIER established a collaboration for the continued development, regulatory approval and commercialization of products comprising or incorporating XOMA’s monoclonal antibody designated XOMA 052 (gevokizumab), and XOMA granted to SERVIER certain exclusive development and commercialization rights therein outside the United States and Japan;

WHEREAS, SERVIER and XOMA are parties to a Loan Agreement entered into as of December 30, 2010, as amended by a Consent, Transfer, Assumption and Amendment Agreement entered into as of August 12, 2013 (as such may be further amended by the parties thereto, the “Loan Agreement”) pursuant to which, among other things, SERVIER made a loan to XOMA; and

WHEREAS, SERVIER and XOMA have agreed to modify the Loan Agreement.

NOW, THEREFORE, in consideration of the mutual covenants set forth herein and other good and valuable consideration, including a modification on even date herewith of the Collaboration Agreement, the Parties hereto mutually agree to amend the Loan Agreement, as follows:

	1.	Definitions. All capitalized terms not otherwise defined herein shall have the meanings assigned to them in the Loan Agreement, except if they are otherwise defined in this Amendment, in which case they shall have the meaning ascribed to them in this Amendment.

	2.	General. Except as expressly set forth herein, the Loan Agreement shall continue in full force and effect and, as modified or amended, is hereby ratified, confirmed and approved. No provision of this Amendment N°1 may be modified or amended except expressly in a writing signed by both Parties nor shall any terms be waived except expressly in a writing signed by both Parties charged therewith.

	ARTICLE 1	AMENDMENT OF THE DEFINITION OF “MATURITY DATE” SET OUT IN ARTICLE 1 OF THE LOAN AGREEMENT

The definition of “Maturity Date” set out in Article 1 of the Loan Agreement is hereby deleted in its entirety and replaced by the following:

“Maturity Date” means the earlier of (i) January 15, 2018, (ii) the date of termination of the Collaboration Agreement by Servier for material breach by XOMA US under Section 11.4 of the Collaboration Agreement, (iii) the second anniversary of the effective date of termination of the Collaboration Agreement under Section 11.3 of the Collaboration Agreement and (iv) the date of assignment by XOMA of the Collaboration Agreement to an Acquiror.

	ARTICLE 2	AMENDMENT OF SECTIONS 3.2 AND 3.3 OF THE LOAN AGREEMENT

Sections 3.2 and 3.3 of the Loan Agreement are hereby deleted in their entirety and replaced by the following:

3.2            Principal Repayment.  XOMA US shall make the following principal repayment payments to SERVIER:

		(a)	three million euros (€3,000,000) on January 15, 2016,

		(b)	five million euros (€5,000,000) on January 15, 2017, and

		(c)	seven million euros (€7,000,000) on the Maturity Date.

For the avoidance of doubt, notwithstanding any provision to the contrary (including Section 3.1(c) and the above terms in this Section 3.2), all outstanding principal, together with all accrued and unpaid interest, shall be due and payable by XOMA US on the Maturity Date, even if such Maturity Date (as determined according to the definition thereof set out in Article 1) occurs prior to one or more of the repayment dates set out above.

[*] = Certain confidential information contained in this document, marked by brackets, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended.

 

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3.3            Right of Offset.  From and after the Repayment Commencement Date, Servier may, at its election upon written notice to XOMA US, withhold from XOMA US and apply to the principal amount of the Advance an amount up to [*]% of any milestone payment owing from Servier to XOMA US under the Collaboration Agreement and [*]% of any royalty payment owing by Servier to XOMA US under the Collaboration Agreement.  Upon such application, Servier shall be deemed to have satisfied its obligation to pay the withheld amount to XOMA US in respect of the applicable milestone or royalty payment, and XOMA US shall be deemed to have discharged the principal amount of the Advance in the amount so applied, the amount so discharged by XOMA US being applied to the next principal repayment(s) due in accordance with Section 3.2. Servier shall have the right to set-off or apply any amounts owed by Servier or any of its Affiliates to XOMA US or any of its Affiliates against the Indebtedness hereunder in case of an Event of Default.  Except as expressly permitted under this Section 3.3, Servier shall not have any right to set-off or apply any amounts owed by Servier or any of its Affiliates to XOMA US or any of its Affiliates against the Indebtedness hereunder.

	
ARTICLE 3

	
OTHER PROVISIONS

XOMA and SERVIER hereby covenant that each will, at any time and from time to time upon request by any other, and without the assumption of any additional liability thereby, execute and deliver such further documents and do such further acts as such party may reasonably request in order to fully effect the purpose of this Amendment N°2.

It is understood between the Parties that XOMA shall assume all costs related to any administrative registration that is reasonably required to give fully effect to this Amendment N°2.

This Amendment N°2 may be executed in any number of counterparts, each of which shall be deemed an original, but all of which when taken together shall constitute but one and the same agreement.

All other terms of the Loan Agreement shall remain in full force and effect.

 

[*] = Certain confidential information contained in this document, marked by brackets, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended.

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IN WITNESS WHEREOF, the undersigned by their duly authorised representatives have executed this Amendment Agreement on the date set forth below.

In Suresnes and San Francisco, on December __, 2014

	
/s/ Pascal Touchon

	 	
/s/ James R. Neal

	
LES LABORATOIRES SERVIER

	 	
XOMA (US) LLC

	
By: Mr. Pascal Touchon

	 	
By: James R. Neal

	
Title: Proxy

	 	
Name: James R. Neal

	 	 	
Title: VP, Business Development

	 	 	
Dated: January 9, 2015

	 	 	 
	
/s/ Marie-Christine Larcher

	 	 
	
INSTITUT DE RECHERCHES SERVIER

	 	 
	
By: Mrs. Marie-Christine Larcher

	 	 
	
Title: Proxy

	 	 

 

[*] = Certain confidential information contained in this document, marked by brackets, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended.

 

 

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