Document:

EX-10.1

 Exhibit 10.1 

INDEMNIFICATION AGREEMENT 

This Indemnification Agreement (this “Agreement”) is entered into as of __________ by and between Progenity, Inc., a Delaware
corporation (the “Company”), and __________ (the “Indemnitee”) and shall be deemed effective upon the earliest date that the Indemnitee is duly elected or appointed as a director or officer of the Company. 

RECITALS 
 WHEREAS, the
Board of Directors has determined that the inability to attract and retain qualified persons as directors and officers is detrimental to the best interests of the Company’s stockholders and that the Company should act to assure such persons
that there shall be adequate certainty of protection through insurance and indemnification against risks of claims and actions against them arising out of their service to and activities on behalf of the Company; 

WHEREAS, the Company has adopted provisions in its Restated Certificate of Incorporation and Bylaws providing for indemnification and
advancement of expenses of its directors and officers to the fullest extent authorized by the General Corporation Law of the State of Delaware (the “DGCL”), and the Company wishes to clarify and enhance the rights and obligations of
the Company and the Indemnitee with respect to indemnification and advancement of expenses; 
 WHEREAS, in order to induce and encourage
highly experienced and capable persons such as the Indemnitee to serve and continue to serve as directors and officers of the Company and in any other capacity with respect to the Company as the Company may request, and to otherwise promote the
desirable end that such persons shall resist what they consider unjustified lawsuits and claims made against them in connection with the good faith performance of their duties to the Company, with the knowledge that certain costs, judgments,
penalties, fines, liabilities, and expenses incurred by them in their defense of such litigation are to be borne by the Company and they shall receive the maximum protection against such risks and liabilities as may be afforded by applicable law,
the Board of Directors of the Company has determined that the following Agreement is reasonable and prudent to promote and ensure the best interests of the Company and its stockholders; and 

WHEREAS, the Company desires to have the Indemnitee serve or continue to serve as a director or officer of the Company and in any other
capacity with respect to the Company as the Company may request, as the case may be, free from undue concern for unpredictable, inappropriate, or unreasonable legal risks and personal liabilities by reason of the Indemnitee acting in good faith in
the performance of the Indemnitee’s duty to the Company; and the Indemnitee desires to continue so to serve the Company, provided, and on the express condition, that he or she is furnished with the protections set forth hereinafter. 

AGREEMENT 
 NOW,
THEREFORE, in consideration of the Indemnitee’s continued service as a director or officer of the Company, the parties hereto agree as follows: 

 1. Definitions. For purposes of this Agreement: 

(a) A “Change in Control” will be deemed to have occurred if, with respect to any particular
24-month period, the individuals who, at the beginning of such 24-month period, constituted the Board of Directors of the Company (the “Incumbent
Board”) cease for any reason to constitute at least a majority of the Board of Directors; provided, however, that any individual becoming a director subsequent to the beginning of such
24-month period whose election, or nomination for election by the stockholders of the Company, was approved by a vote of at least a majority of the directors then comprising the Incumbent Board shall be
considered as though such individual were a member of the Incumbent Board, but excluding, for this purpose, any such individual whose initial assumption of office occurs as a result of an actual or threatened election contest with respect to the
election or removal of directors or other actual or threatened solicitation of proxies or consents by or on behalf of a person other than the Board of Directors. 

(b) “Disinterested Director” means a director of the Company who is not or was not a party to the Proceeding in respect of
which indemnification is being sought by the Indemnitee. 
 (c) “Expenses” includes, without limitation, expenses incurred
in connection with the defense or settlement of any action, suit, arbitration, alternative dispute resolution mechanism, inquiry, judicial, administrative, or legislative hearing, investigation, or any other threatened, pending, or completed
proceeding, whether brought by or in the right of the Company or otherwise, including any and all appeals, whether of a civil, criminal, administrative, legislative, investigative, or other nature, attorneys’ fees, witness fees and expenses,
fees and expenses of accountants and other advisors, retainers and disbursements and advances thereon, the premium, security for, and other costs relating to any bond (including cost bonds, appraisal bonds, or their equivalents), and any expenses of
establishing a right to indemnification or advancement under this Agreement, but shall not include the amount of judgments, fines, ERISA excise taxes, or penalties actually levied against the Indemnitee, or any amounts paid in settlement by or on
behalf of the Indemnitee. 
 (d) “Independent Counsel” means a law firm or a member of a law firm that neither is presently
nor in the past five years has been retained to represent (i) the Company or the Indemnitee in any matter material to either such party or (ii) any other party to the Proceeding giving rise to a request for indemnification hereunder.
Notwithstanding the foregoing, the term “Independent Counsel” shall not include any person who, under the applicable standards of professional conduct then prevailing, would have a conflict of interest in representing either the Company or
the Indemnitee in an action to determine the Indemnitee’s right to indemnification under this Agreement. 
 (e)
“Proceeding” means any action, suit, arbitration, alternative dispute resolution mechanism, inquiry, judicial, administrative, or legislative hearing, investigation, or any other threatened, pending, or completed proceeding, whether
brought by or in the right of the Company or otherwise, including any and all appeals, whether of a civil, criminal, administrative, legislative, investigative, or other nature, to which the Indemnitee was or is a party or is threatened to be made a
party or is otherwise involved in by reason of the fact that the Indemnitee is or was a director, officer, employee, agent, or trustee of the Company or while a 

  
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director, officer, employee, agent, or trustee of the Company is or was serving at the request of the Company as a director, officer, employee, agent, or trustee of another corporation or of a
partnership, joint venture, trust, or other enterprise, including service with respect to an employee benefit plan (such status, the Indemnitee’s “Corporate Status”), or by reason of anything done or not done by the Indemnitee
in any such capacity, whether or not the Indemnitee is serving in such capacity at the time any expense, liability, or loss is incurred for which indemnification or advancement can be provided under this Agreement. 

2. Service by the Indemnitee. The Indemnitee shall serve and/or continue to serve as a director or officer of the Company faithfully and
to the best of the Indemnitee’s ability so long as the Indemnitee is duly elected or appointed and until such time as the Indemnitee’s successor is elected and qualified or the Indemnitee is removed as permitted by applicable law or
tenders a resignation in writing. 
 3. Indemnification and Advancement of Expenses. The Company shall indemnify and hold harmless the
Indemnitee, and shall pay to the Indemnitee in advance of the final disposition of any Proceeding all Expenses incurred by the Indemnitee in defending any such Proceeding, to the fullest extent authorized by the DGCL, as the same exists or may
hereafter be amended, all on the terms and conditions set forth in this Agreement. Without diminishing the scope of the rights provided by this Section, the rights of the Indemnitee to indemnification and advancement of Expenses provided hereunder
shall include but shall not be limited to those rights hereinafter set forth, except that no indemnification or advancement of Expenses shall be paid to the Indemnitee: 

(a) to the extent expressly prohibited by applicable law or the Restated Certificate of Incorporation and Bylaws of the Company; 

(b) for and to the extent that payment is actually made to the Indemnitee under a valid and collectible insurance policy or under a valid and
enforceable indemnity clause, provision of the certificate of incorporation or bylaws, or agreement of the Company or any other company or other enterprise (and the Indemnitee shall reimburse the Company for any amounts paid by the Company and
subsequently so recovered by the Indemnitee); or 
 (c) in connection with an action, suit, or proceeding, or part thereof initiated by the
Indemnitee (including claims and counterclaims, whether such counterclaims are asserted by (i) the Indemnitee, or (ii) the Company in an action, suit, or proceeding initiated by the Indemnitee), except a judicial proceeding pursuant to
Section 11 to enforce rights under this Agreement, unless (A) the action, suit, or proceeding, or part thereof, was authorized or ratified by the Board of Directors of the Company or (B) the Company provides the indemnification, in
its sole discretion, pursuant to the powers vested in the Company under applicable law. 
 4. Action or Proceedings Other than an Action
by or in the Right of the Company. Except as limited by Section 3 above, the Indemnitee shall be entitled to the indemnification rights provided in this Section if the Indemnitee was or is a party or is threatened to be made a party to, or
was or is otherwise involved in, any Proceeding (other than an action by or in the right of the Company) by reason of the Indemnitee’s Corporate Status, or by reason of anything done or not done by the Indemnitee in any such capacity. Pursuant
to this Section, the 

  
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Indemnitee shall be indemnified against all expense, liability, and loss (including judgments, fines, ERISA excise taxes or penalties, amounts paid in settlement by or on behalf of the
Indemnitee, and Expenses) actually and reasonably incurred by the Indemnitee, or on behalf of the Indemnitee, in connection with such Proceeding, if the Indemnitee acted in good faith and in a manner the Indemnitee reasonably believed to be in or
not opposed to the best interests of the Company, and with respect to any criminal Proceeding, had no reasonable cause to believe his or her conduct was unlawful. 

5. Indemnity in Proceedings by or in the Right of the Company. Except as limited by Section 3 above, the Indemnitee shall be
entitled to the indemnification rights provided in this Section if the Indemnitee was or is a party or is threatened to be made a party to, or was or is otherwise involved in, any Proceeding brought by or in the right of the Company to procure a
judgment in its favor by reason of the Indemnitee’s Corporate Status, or by reason of anything done or not done by the Indemnitee in any such capacity. Pursuant to this Section, the Indemnitee shall be indemnified against all Expenses actually
and reasonably incurred by the Indemnitee, or on behalf of the Indemnitee, in connection with such Proceeding if the Indemnitee acted in good faith and in a manner the Indemnitee reasonably believed to be in or not opposed to the best interests of
the Company; provided, however, that no such indemnification shall be made in respect of any claim, issue, or matter as to which the DGCL expressly prohibits such indemnification by reason of any adjudication of liability of the
Indemnitee to the Company, unless and only to the extent that the Court of Chancery of the State of Delaware or the court in which such Proceeding was brought shall determine upon application that, despite the adjudication of liability but in view
of all the circumstances of the case, the Indemnitee is entitled to indemnification for such expense, liability, and loss as such court shall deem proper. 

6. Indemnification for Costs, Charges, and Expenses of Successful Party. Notwithstanding any limitations of Sections 3(c), 4, and 5
above, to the extent that the Indemnitee has been successful, on the merits or otherwise, in whole or in part, in defense of any Proceeding, or in defense of any claim, issue, or matter therein, including, without limitation, the dismissal of any
action without prejudice, or if it is ultimately determined, by final judicial decision of a court of competent jurisdiction from which there is no further right to appeal, that the Indemnitee is otherwise entitled to be indemnified against
Expenses, the Indemnitee shall be indemnified against all Expenses actually and reasonably incurred by the Indemnitee in connection therewith. For purposes of this Section and without limitation, the termination of any claim, issue or matter in such
a Proceeding by dismissal, with or without prejudice, shall be deemed to be a successful result as to such claim, issue or matter. 
 7.
Partial Indemnification. If the Indemnitee is entitled under any provision of this Agreement to indemnification by the Company for some or a portion of the expense, liability, and loss (including judgments, fines, ERISA excise taxes or
penalties, amounts paid in settlement by or on behalf of the Indemnitee, and Expenses) actually and reasonably incurred in connection with any Proceeding, or in connection with any judicial proceeding pursuant to Section 11 to enforce rights
under this Agreement, but not, however, for all of the total amount thereof, the Company shall nevertheless indemnify the Indemnitee for the portion of such expense, liability, and loss actually and reasonably incurred to which the Indemnitee is
entitled. 

  
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 8. Indemnification for Expenses of a Witness. Notwithstanding any other provision of
this Agreement, to the maximum extent permitted by the DGCL, the Indemnitee shall be entitled to indemnification against all Expenses actually and reasonably incurred by the Indemnitee or on the Indemnitee’s behalf if the Indemnitee appears as
a witness, responds to a discovery request or otherwise incurs legal expenses as a result of or related to the Indemnitee’s service as a director or officer of the Company, in any threatened, pending, or completed action, suit, arbitration,
alternative dispute resolution mechanism, inquiry, judicial, administrative, or legislative hearing, investigation, or any other threatened, pending, or completed proceeding, whether of a civil, criminal, administrative, legislative, investigative,
or other nature, to which the Indemnitee neither is, nor is threatened to be made, a party. 
 9. Determination of Entitlement to
Indemnification. To receive indemnification under this Agreement, the Indemnitee shall submit a written request to the Secretary of the Company. Such request shall include documentation or information that is necessary for such determination and
is reasonably available to the Indemnitee. Notwithstanding the foregoing, any failure of the Indemnitee to provide such a request to the Company, or to provide such a request in a timely fashion, shall not relieve the Company of any liability that
it may have to the Indemnitee unless, and to the extent that, such failure actually and materially prejudices the interests of the Company. Upon receipt by the Secretary of the Company of a written request by the Indemnitee for indemnification
pursuant to this Agreement, the entitlement of the Indemnitee to indemnification, to the extent not provided pursuant to the terms of this Agreement, shall be determined by the following person or persons who shall be empowered to make such
determination (as selected by the Board of Directors, except with respect to Section 9(e) below): (a) the Board of Directors by a majority vote of Disinterested Directors, whether or not such majority constitutes a quorum; (b) a committee
of Disinterested Directors designated by a majority vote of such directors, whether or not such majority constitutes a quorum; (c) if there are no Disinterested Directors, or if the Disinterested Directors so direct, by Independent Counsel in a
written opinion to the Board of Directors, a copy of which shall be delivered to the Indemnitee; (d) the stockholders of the Company; or (e) in the event that a Change in Control has occurred, at the option of the Indemnitee, by
Independent Counsel in a written opinion to the Board of Directors, a copy of which shall be delivered to the Indemnitee. Such Independent Counsel shall be selected by the Board of Directors and approved by the Indemnitee, except that in the event
that a Change in Control has occurred, Independent Counsel shall be selected by the Indemnitee. Upon failure of the Board of Directors so to select such Independent Counsel or upon failure of the Indemnitee so to approve (or so to select, in the
event a Change in Control has occurred), such Independent Counsel shall be selected upon application to a court of competent jurisdiction. The determination of entitlement to indemnification shall be made and, unless a contrary determination is
made, such indemnification shall be paid in full by the Company not later than the earlier of (i) 60 calendar days after receipt by the Secretary of the Company of a written request for indemnification and (ii) 10 calendar days after determination
has been made that the Indemnitee is entitled to indemnification pursuant to Section 10 of this Agreement. If the person making such determination shall determine that the Indemnitee is entitled to indemnification as to part (but not all) of
the application for indemnification, such person shall reasonably prorate such partial indemnification among the claims, issues, or matters at issue at the time of the determination. 

  
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 10. Presumptions and Effect of Certain Proceedings. The Secretary of the Company
shall, promptly upon receipt of the Indemnitee’s written request for indemnification, advise in writing the Board of Directors or such other person or persons empowered to make the determination as provided in Section 9 that the Indemnitee
has made such request for indemnification. Upon making such request for indemnification, the Indemnitee shall be presumed to be entitled to indemnification hereunder and the Company shall have the burden of proof in making any determination contrary
to such presumption. If the person or persons so empowered to make such determination shall have failed to make the requested determination with respect to indemnification within 60 calendar days after receipt by the Secretary of the Company of such
request, a requisite determination of entitlement to indemnification shall be deemed to have been made and the Indemnitee shall be absolutely entitled to such indemnification, absent actual fraud in the request for indemnification. The termination
of any Proceeding described in Sections 4 or 5 by judgment, order, settlement, or conviction, or upon a plea of nolo contendere or its equivalent, shall not, of itself (a) create a presumption that the Indemnitee did
not act in good faith and in a manner the Indemnitee reasonably believed to be in or not opposed to the best interests of the Company, or with respect to any criminal Proceeding, had reasonable cause to believe his or her conduct was unlawful or
(b) otherwise adversely affect the rights of the Indemnitee to indemnification except as may be provided herein. 
 11. Remedies of
the Indemnitee in Cases of Determination Not to Indemnify or to Advance Expenses; Right to Bring Suit. In the event that a determination is made that the Indemnitee is not entitled to indemnification hereunder or if payment is not timely made
following a determination of entitlement to indemnification pursuant to Sections 9 and 10, or if an advancement of Expenses is not timely made pursuant to Section 16, the Indemnitee may at any time thereafter bring suit against the Company
seeking an adjudication of entitlement to such indemnification or advancement of Expenses, and any such suit shall be brought in the Court of Chancery of the State of Delaware unless, if the Indemnitee is an employee of the Company, otherwise
required by the law of the state in which the Indemnitee primarily resides and works. The Company shall not oppose the Indemnitee’s right to seek any such adjudication. In any suit brought by the Indemnitee to enforce a right to indemnification
hereunder (but not in a suit brought by the Indemnitee to enforce a right to an advancement of Expenses), it shall be a defense that the Indemnitee did not act in good faith and in a manner the Indemnitee reasonably believed to be in or not opposed
to the best interests of the Company and, with respect to any criminal Proceeding, had no reasonable cause to believe his or her conduct was unlawful. Further, in any suit brought by the Company to recover an advancement of Expenses pursuant to the
terms of an undertaking, the Company shall be entitled to recover such Expenses upon a final judicial decision of a court of competent jurisdiction from which there is no further right to appeal that the Indemnitee has not met the standard of
conduct described above. Neither the failure of the Company (including the Disinterested Directors, a committee of Disinterested Directors, Independent Counsel, or its stockholders) to have made a determination prior to the commencement of such suit
that indemnification of the Indemnitee is proper in the circumstances because the Indemnitee has met the standard of conduct described above, nor an actual determination by the Company (including the Disinterested Directors, a committee of
Disinterested Directors, Independent Counsel, or its stockholders) that the Indemnitee has not met the standard of conduct described above shall create a presumption that the Indemnitee has not met the standard of conduct described above, or, in the
case of such a suit brought by the Indemnitee, be a defense to such suit. In any suit brought by the Indemnitee to enforce a right to 

  
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indemnification or to an advancement of Expenses hereunder, or brought by the Company to recover an advancement of Expenses pursuant to the terms of an undertaking, the burden of proving that the
Indemnitee is not entitled to be indemnified, or to such advancement of expenses, under this Section 11 or otherwise shall be on the Company. If a determination is made or deemed to have been made pursuant to the terms of Section 9 or 10
that the Indemnitee is entitled to indemnification, the Company shall be bound by such determination and is precluded from asserting that such determination has not been made or that the procedure by which such determination was made is not valid,
binding, and enforceable. The Company further agrees to stipulate in any court pursuant to this Section 11 that the Company is bound by all the provisions of this Agreement and is precluded from making any assertions to the contrary. If the
court shall determine that the Indemnitee is entitled to any indemnification or advancement of Expenses hereunder, the Company shall pay all Expenses actually and reasonably incurred by the Indemnitee in connection with such adjudication (including,
but not limited to, any appellate proceedings) to the fullest extent permitted by law, and in any suit brought by the Company to recover an advancement of Expenses pursuant to the terms of an undertaking, the Company shall pay all Expenses actually
and reasonably incurred by the Indemnitee in connection with such suit to the extent the Indemnitee has been successful, on the merits or otherwise, in whole or in part, in defense of such suit, to the fullest extent permitted by law. 

12. Non-Exclusivity of Rights; Survival of Rights; Insurance; Subrogation. 

(a) The rights provided by this Agreement shall not be deemed exclusive of any other rights to which the Indemnitee may at any time be entitled
under applicable law, the certificate of incorporation and the bylaws of the Company, any agreement, a vote of stockholders, a resolution of the Board or otherwise. No amendment, alteration or repeal of this Agreement or of any provision of this
Agreement shall limit or restrict any right of the Indemnitee under this Agreement in respect of any action taken or omitted by the Indemnitee in his or her Corporate Status prior to such amendment, alteration or repeal. To the extent that a change
in the DGCL, whether by statute or judicial decision, permits greater indemnification than would be afforded currently under the certificate of incorporation, the bylaws of the Company and this Agreement, it is the intent of the parties hereto that
the Indemnitee shall enjoy by this Agreement the greater benefits so afforded by such change. No right or remedy herein conferred is intended to be exclusive of any other right or remedy, and every other right and remedy shall be cumulative and in
addition to every other right and remedy given hereunder or now or hereafter existing at law or in equity or otherwise. The assertion or employment of any right or remedy hereunder, or otherwise, shall not prevent the concurrent assertion or
employment of any other right or remedy. 
 (b) To the extent that the Company maintains an insurance policy or policies providing liability
insurance for directors, officers, employees, or agents or fiduciaries of the Company or of any other corporation, partnership, joint venture, trust, employee benefit plan or other enterprise that such person serves at the request of the Company,
the Company shall obtain coverage for the Indemnitee under such policy or policies in accordance with its or their terms to the maximum extent of the coverage available for any other director (if the Indemnitee is a director), or officer (if the
Indemnitee is not a director but is an officer), of the Company under such policy or policies. If, at the time of the receipt of a notice of a claim pursuant to the terms of this Agreement, the Company has director and officer liability insurance in
effect, the 

  
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Company shall give prompt notice of the commencement of such proceeding to the insurers in accordance with the procedures set forth in the respective policies. The Company shall thereafter take
all commercially reasonable steps to cause such insurers to pay, on behalf of the Indemnitee, all amounts payable as a result of such proceeding in accordance with the terms of such policies. 

(c) In the event of any payment under this Agreement, the Company shall be subrogated to the extent of such payment to all of the rights of
recovery of the Indemnitee, who shall execute all papers required and take all action necessary to secure such rights, including execution of such documents as are necessary to enable the Company effectively to bring suit to enforce such rights.

 (d) The Company shall not be liable under this Agreement to make any payment of amounts otherwise indemnifiable hereunder if and to the
extent that the Indemnitee has otherwise actually received such payment under any insurance policy, contract, agreement or otherwise. 
 (e)
The Company’s obligation to indemnify or advance Expenses hereunder to the Indemnitee who is or was serving at the request of the Company as a director, officer, employee or agent of any other corporation, partnership, joint venture, trust,
employee benefit plan or other enterprise shall be reduced by any amount the Indemnitee has actually received as indemnification or advancement of expenses from such other corporation, partnership, joint venture, trust, employee benefit plan or
other enterprise. 
 13. Expenses to Enforce Agreement. In the event that the Indemnitee is subject to or intervenes in any action,
suit, or proceeding in which the validity or enforceability of this Agreement is at issue or seeks an adjudication to enforce the Indemnitee’s rights under, or to recover damages for breach of, this Agreement, the Indemnitee, if the Indemnitee
prevails in whole or in part in such action, suit, or proceeding, shall be entitled to recover from the Company and shall be indemnified by the Company against any Expenses actually and reasonably incurred by the Indemnitee in connection therewith.

 14. Continuation of Indemnity. All agreements and obligations of the Company contained herein shall continue during the period the
Indemnitee is a director, officer, employee, agent, or trustee of the Company or while a director, officer, employee, agent, or trustee is serving at the request of the Company as a director, officer, employee, agent, or trustee of another
corporation or of a partnership, joint venture, trust, or other enterprise, including service with respect to an employee benefit plan, and shall continue thereafter with respect to any possible claims based on the fact that the Indemnitee was a
director, officer, employee, agent, or trustee of the Company or was serving at the request of the Company as a director, officer, employee, agent, or trustee of another corporation or of a partnership, joint venture, trust, or other enterprise,
including service with respect to an employee benefit plan. This Agreement shall be binding upon all successors and assigns of the Company (including any transferee of all or substantially all of its assets and any successor by merger or operation
of law) and shall inure to the benefit of the Indemnitee’s heirs, executors, and administrators. 

  
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 15. Notification and Defense of Proceeding. Promptly after receipt by the Indemnitee
of notice of any Proceeding, the Indemnitee shall, if a request for indemnification or an advancement of Expenses in respect thereof is to be made against the Company under this Agreement, notify the Company in writing of the commencement thereof;
but the omission so to notify the Company shall not relieve it from any liability that it may have to the Indemnitee unless, and to the extent that, such failure actually and materially prejudices the interests of the Company. Notwithstanding any
other provision of this Agreement, with respect to any such Proceeding of which the Indemnitee notifies the Company: 
 (a) The Company shall
be entitled to participate therein at its own expense; 
 (b) Except as otherwise provided in this Section 15(b), to the extent that it
may wish, the Company, jointly with any other indemnifying party similarly notified, shall be entitled to assume the defense thereof, with counsel satisfactory to the Indemnitee. After notice from the Company to the Indemnitee of its election so to
assume the defense thereof, the Company shall not be liable to the Indemnitee under this Agreement for any expenses of counsel subsequently incurred by the Indemnitee in connection with the defense thereof except as otherwise provided below. The
Indemnitee shall have the right to employ the Indemnitee’s own counsel in such Proceeding, but the fees and expenses of such counsel incurred after notice from the Company of its assumption of the defense thereof shall be at the expense of the
Indemnitee unless (i) the employment of counsel by the Indemnitee has been authorized by the Company, (ii) the Indemnitee shall have reasonably concluded that there may be a conflict of interest between the Company and the Indemnitee in
the conduct of the defense of such Proceeding, or (iii) the Company shall not within 60 calendar days of receipt of notice from the Indemnitee in fact have employed counsel to assume the defense of the Proceeding, in each of which cases the
fees and expenses of the Indemnitee’s counsel shall be at the expense of the Company. The Company shall not be entitled to assume the defense of any Proceeding brought by or on behalf of the Company or as to which the Indemnitee shall have made
the conclusion provided for in (ii) above; and 
 (c) Notwithstanding any other provision of this Agreement, the Company shall not be
liable to indemnify the Indemnitee under this Agreement for any amounts paid in settlement of any Proceeding effected without the Company’s written consent, or for any judicial or other award, if the Company was not given an opportunity, in
accordance with this Section 15, to participate in the defense of such Proceeding. The Company shall not settle any Proceeding in any manner that would impose any penalty or limitation on or disclosure obligation with respect to the Indemnitee,
or that would directly or indirectly constitute or impose any admission or acknowledgement of fault or culpability with respect to the Indemnitee, without the Indemnitee’s written consent. Neither the Company nor the Indemnitee shall
unreasonably withhold its consent to any proposed settlement. 
 16. Advancement of Expenses. All Expenses incurred by the Indemnitee
in defending any Proceeding described in Section 4 or 5 shall be paid by the Company in advance of the final disposition of such Proceeding at the request of the Indemnitee. The Indemnitee’s right to advancement shall not be subject to the
satisfaction of any standard of conduct and advances shall be made without regard to the Indemnitee’s ultimate entitlement to indemnification under the provisions of this Agreement or otherwise. To receive an

  
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advancement of Expenses under this Agreement, the Indemnitee shall submit a written request to the Secretary of the Company. Such request shall reasonably evidence the Expenses incurred by the
Indemnitee and shall include or be accompanied by an undertaking, by or on behalf of the Indemnitee, to repay all amounts so advanced if it shall ultimately be determined, by final judicial decision of a court of competent jurisdiction from which
there is no further right to appeal, that the Indemnitee is not entitled to be indemnified for such Expenses by the Company as provided by this Agreement or otherwise. The Indemnitee’s undertaking to repay any such amounts is not required to be
secured. Each such advancement of Expenses shall be made within 20 calendar days after the receipt by the Secretary of the Company of such written request. The Indemnitee’s entitlement to Expenses under this Agreement shall include those
incurred in connection with any action, suit, or proceeding by the Indemnitee seeking an adjudication pursuant to Section 11 of this Agreement (including the enforcement of this provision) to the extent the court shall determine that the
Indemnitee is entitled to an advancement of Expenses hereunder. 
 17. Severability; Prior Indemnification Agreements. If any
provision or provisions of this Agreement shall be held to be invalid, illegal, or unenforceable for any reason whatsoever, (a) the validity, legality, and enforceability of the remaining provisions of this Agreement (including, without
limitation, all portions of any paragraphs of this Agreement containing any such provision held to be invalid, illegal, or unenforceable, that are not by themselves invalid, illegal, or unenforceable) shall not in any way be affected or impaired
thereby, and (b) to the fullest extent possible, the provisions of this Agreement (including, without limitation, all portions of any paragraph of this Agreement containing any such provision held to be invalid, illegal, or unenforceable, that
are not themselves invalid, illegal, or unenforceable) shall be construed so as to give effect to the intent of the parties that the Company provide protection to the Indemnitee to the fullest enforceable extent set forth in this Agreement. This
Agreement shall supersede and replace any prior indemnification agreements entered into by and between the Company and the Indemnitee and any such prior agreements shall be terminated upon execution of this Agreement. 

18. Headings; References; Pronouns. The headings of the sections of this Agreement are inserted for convenience only and shall not be
deemed to constitute part of this Agreement or to affect the construction thereof. References herein to section numbers are to sections of this Agreement. All pronouns and any variations thereof shall be deemed to refer to the singular or plural as
appropriate. 
 19. Other Provisions. 

(a) This Agreement and all disputes or controversies arising out of or related to this Agreement shall be governed by, and construed in
accordance with, the internal laws of the State of Delaware, without regard to the laws of any other jurisdiction that might be applied because of conflicts of laws principles of the State of Delaware, unless, if the Indemnitee is an employee of the
Company, otherwise required by the law of the state in which the Indemnitee primarily resides and works. 

  
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 (b) This Agreement may be executed in two or more counterparts, all of which shall be
considered one and the same instrument and shall become effective when one or more counterparts have been signed by each of the parties and delivered to the other party. 

(c) This Agreement shall not be deemed an employment contract between the Company and any Indemnitee who is an officer of the Company, and, if
the Indemnitee is an officer of the Company, the Indemnitee specifically acknowledges that the Indemnitee may be discharged at any time for any reason, with or without cause, and with or without severance compensation, except as may be otherwise
provided in a separate written contract between the Indemnitee and the Company. 
 (d) This Agreement may not be amended, modified, or
supplemented in any manner, whether by course of conduct or otherwise, except by an instrument in writing specifically designated as an amendment hereto, signed on behalf of each party. No failure or delay of either party in exercising any right or
remedy hereunder shall operate as a waiver thereof, and no single or partial exercise of any such right or power, or any abandonment or discontinuance of steps to enforce such right or power, or any course of conduct, shall preclude any other or
further exercise thereof or the exercise of any other right or power. 
 [The remainder of this page is intentionally left blank.] 

  
 11 

 IN WITNESS WHEREOF, the Company and the Indemnitee have caused this Agreement to be executed
as of the date first written above. 
  

					
	PROGENITY, INC.
		
	By:	 	
                 

		 	Name:	 	Clarke Neumann
		 	Title:	 	General Counsel
	
	  

		 		 	__________, Indemnitee

 [SIGNATURE PAGE TO INDEMNIFICATION
AGREEMENT]EX-10.14

 Exhibit 10.14 

PROGENITY, INC. 

SEVERANCE PLAN 
 SECTION 1.
INTRODUCTION. 
 THE PROGENITY, INC. SEVERANCE PLAN (the “Plan”) was approved by the Compensation Committee of
the Board of Directors of PROGENITY, INC. (the “Company”) on December 4, 2019 and became effective on December 4, 2019. The purpose of the Plan is to provide for the payment of severance benefits to certain selected
executives and other employees of the Company in the event their employment with the Company and any Applicable Subsidiary, as applicable, is terminated involuntarily, as provided herein, and to encourage such executives and other employees to
continue as employees of the Company or an Applicable Subsidiary, as the case may be, in the event of a Change in Control. Except as otherwise stated herein, the Plan shall supersede any severance benefit plan, policy or practice previously
maintained by the Company with respect to an executive or employee of the Company who is a Potential Eligible Participant. This Plan document also is the Summary Plan Description for the Plan. Capitalized terms used in the Plan, unless defined
elsewhere in the Plan, shall have the meaning set forth in Section 3 below. 
 SECTION 2. ELIGIBILITY FOR BENEFITS. 

(a) General Rules. Subject to the requirements set forth in this Section 2, the Company will provide
severance benefits under the Plan to each Eligible Participant. 
 (i) “Potential Eligible Participant” refers to the
executives and other employees employed by the Company or any Applicable Subsidiary and designated as a Potential Eligible Participant by the Plan Administrator. No employee whose primary place of business for the Company is outside of the United
States (unless such employee is a citizen or resident alien of the United States) may be designated as a Potential Eligible Participant. An “Eligible Participant” is any Potential Eligible Participant, other than those excluded
under Section 2(b) below, whose employment with the Company or any Applicable Subsidiary is either (A) involuntarily terminated for a reason other than Cause or (B) voluntarily terminated for Good Reason
(collectively, a “Termination Event”). Additionally, an Eligible Participant shall be eligible for additional benefits under the Plan if the Termination Event occurs during the Change in Control Period. For the avoidance of doubt,
(1) a Potential Eligible Participant who is involuntarily terminated for Cause shall not be eligible for benefits under the Plan, and (2) termination of employment on account of death or Disability shall not be treated as a Termination
Event. For purposes of the Plan, the term “United States” shall mean one of the fifty (50) states or the District of Columbia. 

(ii) In order to be eligible to receive benefits under the Plan, in addition to meeting the requirements of an “Eligible Participant”
set forth in Section 2(a)(i) above, an Eligible Participant must execute within 21 days, unless a longer period is required by law or a shorter period is permitted by law, of the Eligible Participant’s receipt
thereof (A) a general waiver and release on the form provided by the Company and (B) other than on account of a Change in Control Termination Event, an agreement containing certain covenants on the form provided by the Company and covering
the matters set forth in Section 6 of the Plan, the scope and applicability of which covenants shall be determined by the Plan Administrator in its sole discretion (collectively, the “Release and Covenant
Documents”). 

  
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 (iii) Any Termination Event that triggers the payment of benefits under the Plan must occur
during the term of the Plan as specified in Section 9(b); provided that in any event eligibility for benefits shall continue until the expiration of a Change in Control Period (as defined below) if a Change in
Control Period commences while the Plan is in effect. 
 (b) Exceptions. A Potential Eligible Participant who otherwise is an
Eligible Participant will not receive benefits under the Plan in any of the following circumstances: 
 (i) The Potential Eligible
Participant is involuntarily terminated by the Company for any reason other than a reason specified in Section 2(a)(i). 

(ii) The Potential Eligible Participant voluntarily terminates employment with the Company either (A) for any reason other than Good
Reason or (B) for no reason, in either case with or without advance notice. Voluntary terminations include, but are not limited to, death, Disability, resignation, retirement, or failure to return from a leave of absence on the scheduled date.

 SECTION 3. DEFINITIONS. 
 Capitalized
terms used in the Plan, unless defined elsewhere in the Plan, shall have the following meanings: 
 (a) “Applicable
Subsidiary” means all subsidiaries of the Company included on Schedule A attached hereto, and any other entity of which the Company owns, directly or indirectly, more than fifty percent (50%) of such entity’s voting securities or
the activities of such entity are controlled, directly or indirectly, by the Company. 
 (b) “Average Annual
Bonus” means, for any Eligible Participant, the average of such Eligible Participant’s cash incentive bonus earned under a Bonus Plan for the two most recently completed fiscal years preceding such Eligible Participant’s
Termination Date. 
 (c) “Board” means the Board of Directors of the Company. 

(d) “Bonus Plan” means the Company’s annual cash incentive bonus plan applicable to a Potential Eligible
Participant from time to time. For the avoidance of doubt, one-time bonuses paid by the Company to a Potential Eligible Participant that are not paid under a bonus plan described in the preceding sentence
shall not be treated as cash incentive bonuses and therefore shall be excluded from the definition of “Average Annual Bonus” for purposes of the Plan. Examples of such one-time bonuses are sign-on bonuses, special recognition bonuses and guaranteed bonuses. For purposes of the Plan, no Eligible Participant shall be treated as participating in more than one Bonus Plan in any given fiscal year. In the
unlikely event that an Eligible Participant is participating in more than one annual cash incentive bonus plan in a given fiscal year that would otherwise qualify as a Bonus Plan but for the preceding sentence, the annual cash incentive bonus plan
that would produce the largest 

  
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payment under the terms of the Plan shall be treated as the Bonus Plan for such Eligible Participant for the applicable fiscal year. 

(e) “Cause” for termination of a Potential Eligible Participant’s employment means (i) if the Potential
Eligible Participant is a party to any written agreement with the Company or any affiliate immediately prior to such termination, and “Cause” is defined therein, then “Cause” shall have the meaning set forth in such agreement, or
(ii) if the Potential Eligible Participant is not party to any such agreement with the Company or any affiliate defining the term “Cause” immediately prior to such termination, then “Cause” shall mean: (A) the Potential
Eligible Participant’s willful and material failure to perform his or her duties and responsibilities to the Company or any affiliate or material violation of a policy of the Company or any affiliate; (B) the Potential Eligible
Participant’s commission of any act of fraud, embezzlement, dishonesty or any other misconduct that has caused or is reasonably expected to result in material injury to the Company or any affiliate; (C) unauthorized use or disclosure by
the Potential Eligible Participant of any proprietary information or trade secrets of the Company or any other Person to whom the Potential Eligible Participant owes an obligation of nondisclosure as a result of his or her relationship with the
Company or any affiliate that has caused or is reasonably expected to result in material injury to the Company or any affiliate; or (D) the Potential Eligible Participant’s material breach of any of his or her obligations under any written
agreement or covenant, including those covenants set forth in Section 6 hereof, with the Company or any affiliate. The determination as to whether a Potential Eligible Participant is being terminated for Cause will be made
in good faith by the Plan Administrator and will be final and binding on the Potential Eligible Participant and any other Person having an interest in such determination. Any determination by the Plan Administrator that the employment of a Potential
Eligible Participant was terminated with or without Cause for the purposes of benefits under the Plan will have no effect upon any determination of the rights or obligations of the Company, any affiliate or such Potential Eligible Participant for
any other purpose. 
 (f) “Change in Control” shall have the same meaning as the definition of “Change in
Control” set forth in Section 13(h) of the Progenity, Inc. 2018 Equity Incentive Plan, as amended from time to time (the “Equity Plan”). In addition, in order to qualify as a “Change in Control,” an event must
also meet the requirements for a “change in the ownership or effective control of a corporation, or a change in the ownership of a substantial portion of the assets of a corporation” within the meaning of Treas. Reg. §1.409A-3(i)(5). 
 (g) “Change in Control Period” means the period beginning
on the date that is three (3) months preceding the effective date of a Change in Control and ending on the date that is thirteen (13) months following the effective date of the Change in Control. For the avoidance of doubt, no enhanced
benefits payable to an Eligible Participant due to a Termination Event occurring within a Change in Control Period shall be paid prior to the effective date of a Change in Control. 

  
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 (h) “Change in Control Termination Event” means the occurrence
of a Termination Event during the Change in Control Period. 
 (i) “Code” means the Internal Revenue Code of 1986, as
amended. Any specific reference to a section of the Code shall be deemed to include any regulations and other Treasury Department guidance promulgated thereunder. 

(j) “Company” means Progenity, Inc., a Delaware corporation, and any successor as provided in
Section 9(c) hereof. 
 (k) Disability means, with respect to the Potential Eligible Participant, the
inability of such Potential Eligible Participant to engage in any substantial gainful activity, despite reasonable accommodation, by reason of any medically determinable physical or mental impairment that can be expected to result in death or that
has lasted (x) for a period of 180 consecutive days or (y) an aggregate of six (6) months in any 12 consecutive month period. Any question as to the existence of that Potential Eligible Participant’s physical or mental impairment
as to which the Potential Eligible Participant or the Potential Eligible Participant’s representative and the Company cannot agree shall be determined in writing by a qualified independent physician mutually acceptable to the Potential Eligible
Participant and the Company. If the Potential Eligible Participant and the Company cannot agree as to a qualified independent physician, each shall appoint such a physician and those two physicians shall select a third who shall make such
determination in writing. The determination of “Disability” made in writing to the Company and the Potential Eligible Participant shall be final and conclusive for all purposes of the benefits under this Plan. 

(l) “Exchange Act” means the Securities Exchange Act of 1934, as amended. 

(m) “Good Reason” for termination of the Potential Eligible Participant’s employment means (i) if the
Potential Eligible Participant is a party to an employment or other written agreement with the Company or any affiliate immediately prior to such termination, and “good reason” is defined therein, then “Good Reason” shall have
the meaning set forth in such agreement, or (ii) if the Potential Eligible Participant is not party to an employment or other written agreement with the Company or any affiliate immediately prior to such termination that contains a definition
of “Good Reason, ” then “Good Reason” shall mean, without the consent of the Potential Eligible Participant: (A) a substantial adverse change in the nature or scope of the Potential Eligible Participant’s
responsibilities, authorities, powers, functions, or duties with the Company or Applicable Subsidiary, as applicable; (B) a material breach by the Company of any of its material obligations hereunder; or (C) a change in the Potential
Eligible Participant’s primary place of work that increases the Potential Eligible Participant’s one-way commute by more than fifty (50) miles. Unless otherwise provided in an employment or
other written agreement to which the Potential Eligible Participant is a party with the Company or any affiliate thereof immediately prior to such termination, to constitute “good reason termination,” the Potential Eligible Participant
must: (1) provide written notice to the Company within 90 days of the initial existence of the event constituting “Good Reason”; (2) may not terminate his or 

  
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her employment unless the Company fails to substantially remedy the event constituting “Good Reason” within 30 days after such notice has been given; and (3) the Potential Eligible
Participant must terminate employment with the Company or the Applicable Subsidiary no later than 30 days after the end of the 30-day period in which the Company fails to substantially remedy the event
constituting “Good Reason.” 
 (n) “IRS” means the Internal Revenue Service. 

(o) “Pay” means, for any Eligible Participant, such Eligible Participant’s monthly base pay at the rate in effect
on the Termination Date (or if greater, the last regularly scheduled payroll period immediately preceding either a Change in Control or a reduction that gave rise to a termination for Good Reason, as applicable). 

(p) “Payment Confirmation Date” means the latest of the following dates: (i) the date of the Termination
Event, (ii) the Termination Date, (iii) the date of receipt of executed Release and Covenant Documents by the Company or (iv) the end of any waiting period or revocation period as required by applicable law in order for the general
waiver and release required by Section 2(a)(ii) of the Plan to be effective. 
 (q) Person means
a “person” as defined in Section 3(a)(9) of the Exchange Act and used in Section 13(d) and 14(d) thereof, including a “group” as defined in Section 13(d) thereof. 

(r) “Plan” means this Progenity, Inc. Severance Plan. 

(s) “Severance Period” means, for any Eligible Participant, the number of months of Pay, rounded to the nearest whole
month, used for calculating such Eligible Participant’s severance benefits, as specified in the Benefits Schedules attached hereto and the Tier applicable to such Eligible Participant. 

(t) “Termination Date” means, for any Eligible Participant, the last date on which such Eligible Participant is in
active employment status with the Company or any of its affiliates or subsidiaries as determined by the Plan Administrator in its sole and reasonable discretion. 

(u) “Tier” means, for any Eligible Participant, the applicable Tier set forth in the Benefits Schedules attached hereto
that is applicable to such Potential Eligible Participant as designated by the Plan Administrator in its sole discretion and in accordance with the Plan. 

(v) “WARN Act” means the federal Worker Adjustment and Retraining Notification Act and any other comparable law
applicable under the laws of any state or foreign jurisdiction. 

  
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 SECTION 4. AMOUNT OF BENEFIT. 

Severance benefits payable under the Plan are as follows: 

(a) Subject to Section 6(f), Eligible Participant will receive the benefits described in Sections 7 and
8 of the Plan and in the Benefit Schedules attached hereto based upon the Tier applicable to such Eligible Participant. 
 (b)
Notwithstanding any other provision of the Plan to the contrary, any benefits payable to an Eligible Participant under the Plan shall be in lieu of any severance benefits payable by the Company or any affiliate thereof to such individual under any
other arrangement covering the individual, unless expressly otherwise agreed to by the Company in writing. Further, in the event that the Eligible Participant is entitled to receive severance benefits under any agreement or contract with the Company
or an affiliate thereof, any plan, policy, program or other arrangement adopted or established by the Company or affiliate thereof, under the WARN Act or other applicable law providing for payments from the Company or its subsidiaries or affiliates
on account of termination of employment, including pay in lieu of advance notice of termination (“Other Benefits”), any severance benefits payable hereunder shall be reduced by the Other Benefits, but not less than zero. 

SECTION 5. TIME OF PAYMENT AND FORM OF BENEFIT; INDEBTEDNESS. 

(a) Benefits under the Plan shall be paid according to the schedule specified in the Benefits Schedules attached hereto, subject to
Section 6(f) and the following provisions: 
 (i) Any increase to the cash severance benefits payable on account of
the occurrence of a Change in Control Termination Event prior to the commencement of the Change in Control Period (such as when the Termination Event occurs prior to the consummation of the Change in Control) shall be paid (A) as soon as
administratively practicable following the determination of such increased cash severance benefits has occurred with respect to lump sum severance payments or (B) on the remaining payment date(s) with respect to installment payment severance
payments. 
 (ii) Unless otherwise required by applicable law, in no event shall payment of any Plan benefit be due prior to the Eligible
Participant’s Payment Confirmation Date, and any payment shall be deemed to be timely made if paid within 30 business days of such date. 

(iii) Notwithstanding anything to the contrary in this Section 5(a), except for a Change in Control Period
Termination Event, the Plan Administrator may, in its sole discretion, determine an alternate payment schedule for any reason, including, without limitation, to comply with Section 409A of the Code. For a Change in Control Termination Event,
the Plan Administrator may determine an alternate payment schedule only to ensure compliance with applicable law, including but not limited to Section 409A of the Code. 

  
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 (b) Subject to compliance with Section 409A of the Code and other applicable law,
if an Eligible Participant is indebted to the Company or any affiliate at his or her Termination Date, the Company reserves the right to offset any severance payments under the Plan by the amount of such indebtedness. 

SECTION 6. ELIGIBLE PARTICIPANT COVENANTS 

Severance benefits payable under the Plan are conditioned upon and subject to the following covenants made by each Eligible Participant (the
“Covenants”), the scope and applicability of which covenants shall be determined by the Plan Administrator in its sole discretion, but in any event shall not be substantially greater than as set forth in this
Section 6. In the event that an Eligible Participant violates one or more of the covenants set forth in this Section 6, such Eligible Participant shall be treated as having failed to have earned
the right to receive any payments or benefits under the Plan, and shall be obligated to return any payments or benefits previously delivered to such Eligible Participant under the Plan. The Company shall also be entitled to pursue any other remedies
to the fullest extent not prohibited by applicable law as provided herein. 
 (a)
Non-Competition. In the course of the performance of Potential Eligible Participant’s job responsibilities for the Company or its affiliates, Potential Eligible Participant has obtained and will
continue to obtain extensive and valuable knowledge and information concerning the Company’s and such affiliates’ business (including confidential information relating to the Company and such affiliates and their respective operations,
intellectual property, assets, contracts, customers, personnel, plans, marketing plans, research and development plans and prospects). Accordingly, during employment with the Company or such affiliates and for the applicable Severance Period
following Potential Eligible Participant’s termination of employment, Potential Eligible Participant will not engage in any business activities on behalf of any enterprise which competes with the Company or any of its affiliates in the business
of molecular diagnostics and genetic testing services and any other business in which the Company or any controlled affiliate engages as of the Potential Eligible Participant’s date of termination of employment. 

Potential Eligible Participant will be deemed to be engaged in such competitive business activities if Potential Eligible Participant
participates in such a business enterprise as an employee, officer, director, consultant, contractor, agent, partner, member, manager, proprietor, or other provider of services; provided that the ownership of no more than two percent (2%) of
the stock of a publicly traded corporation engaged in a competitive business shall not be deemed to be engaging in competitive business activities. If Potential Eligible Participant provides services to an enterprise that has some activities that
compete with the Company or any of its affiliates in any area described above and other activities that do not compete with the Company or any of its affiliates in any of the areas described above, then so long as Potential Eligible Participant
provides services exclusively to the portion of such enterprise that does not compete with the Company and its affiliates, Potential Eligible Participant will not be deemed to be engaged in a competitive business activity as described in this
Section 6(a). 

  
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 The terms of this Section 6(a) are not intended to and do not
prohibit an Eligible Participant from rendering services to a competitive business, but provide for the right of the Company to cease payments or benefits under the Plan and to obtain the return of any payments or benefits previously delivered to
such Eligible Participant in the event that such Eligible Participant violates this Section 6(a). 
 (b) Non-Solicitation. In the course of the performance of Potential Eligible Participant’s job responsibilities for the Company or its affiliates, Potential Eligible Participant has obtained and will continue
to obtain extensive and valuable knowledge and information concerning the Company’s and such affiliates’ business (including confidential information relating to the Company and such affiliates and their respective operations, intellectual
property, assets, contracts, customers, personnel, plans, marketing plans, research and development plans and prospects). Accordingly, during employment with the Company or its affiliates and for the Severance Period following the end of Potential
Eligible Participant’s employment with the Company or its affiliates, Potential Eligible Employee, to the fullest extent not prohibited by applicable law, directly or indirectly, individually or on behalf of any other person or entity,
including Potential Eligible Participant, will not use confidential information or trade secrets of the Company and its affiliates to encourage, induce, attempt to induce, recruit, attempt to recruit, solicit or attempt to solicit or participate in
any way in hiring or retaining for employment, contractor or consulting opportunities anyone who is employed or providing full-time services as a consultant at that time to the Company or any subsidiary or other affiliate of the Company. 

(c) Protection of Confidential Information. Potential Eligible Participant, both during employment with the Company or its
affiliates and thereafter, shall not, directly or indirectly, disclose or make available to any Person for any reason or purpose whatsoever, any Confidential Information (as defined below) except as may be required for Potential Eligible Participant
to perform in good faith his or her job responsibilities to the Company or its affiliates while employed by the Company or its affiliate. Upon Potential Eligible Participant’s termination of employment, Potential Eligible Participant shall
return to the Company all Confidential Information and shall not retain any Confidential Information in Potential Eligible Participant’s possession that is in written or other tangible form and shall not furnish any such Confidential
Information to any third party, except as provided herein. Notwithstanding the foregoing, this Section 6(c) shall not apply to Confidential Information that (i) was publicly known at the time of disclosure to Potential
Eligible Participant, (ii) becomes publicly known or available thereafter other than by any means in violation of this Section 6 or any other duty owed to the Company or its affiliates by Potential Eligible
Participant, (iii) is lawfully disclosed to Potential Eligible Participant by a third party, or (iv) is required to be disclosed by law or by any court, arbitrator or administrative or legislative body with actual or apparent jurisdiction
to order Potential Eligible Participant to disclose or make accessible any information or is voluntarily disclosed by Potential Eligible Participant to law enforcement or other governmental authorities. Furthermore, in accordance with the Defend
Trade Secrets Act of 2016, Potential Eligible Participant will not be held criminally or civilly liable under any federal or state trade secret law for the disclosure 

  
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of a trade secret that (A) is made (x) in confidence to a federal, state or local government official, either directly or indirectly, or to an attorney; and (y) solely for the
purpose of reporting or investigating a suspected violation of law; or (B) is made in a complaint or other document filed in a lawsuit or other proceeding, if such filing is made under seal. As used in the Plan, Confidential Information means,
without limitation, any non-public confidential or proprietary information disclosed to Potential Eligible Participant or known by Potential Eligible Participant as a consequence of or through Potential
Eligible Participant’s relationship with the Company or its affiliates, in any form, including electronic media. Confidential Information also includes, but is not limited to, the Company’s or its affiliates’ business plans and
financial information, marketing plans, and business opportunities. Nothing herein shall limit in any way any obligation Potential Eligible Participant may have relating to Confidential Information under any other agreement, promise or duty to the
Company or its affiliates, including pursuant to the Company Employee Confidentiality and Proprietary Rights Assignment Agreement (the “ECPRA Agreement”). 

(d) Non-Disparagement. At all times during and following Potential Eligible
Participant’s employment with the Company or its affiliates, except for the purpose of performing services for the Company and its affiliates in good faith, Potential Eligible Participant will not make or direct anyone else to make on Potential
Eligible Participant’s behalf any disparaging or untruthful remarks or statements, whether oral or written, about the Company or its affiliates, their respective operations or products, services, affiliates, officers, directors, employees, or
agents, or issue any communication that reflects adversely on or encourages any adverse action against the Company or its affiliates. Potential Eligible Participant will not make any direct or indirect written or oral statements to the press,
television, radio, on social media or to, on or through other media or other external Persons concerning any matters pertaining to the business and affairs of the Company, its affiliates or any of their respective officers or directors. The
restrictions described in this paragraph shall not apply to any truthful statements made in response to a subpoena or other compulsory legal process or to law enforcement or other governmental authorities. 

(e) It is expressly understood and agreed that although each Eligible Participant and the Company consider the restrictions contained in
the Covenants to be reasonable, if a final judicial determination is made by a court of competent jurisdiction that the time or territory or any other restriction contained in the Covenants is an unenforceable restriction against an Eligible
Participant, for which injunctive relief is unavailable, the provisions of the Covenants shall not be rendered void but shall be deemed amended to apply as to such maximum time and territory and to such maximum extent as such court may judicially
determine or indicate to be enforceable. Furthermore, such a determination shall not limit the Company’s ability to cease providing payments or benefits during the remainder of any Severance Period or to seek recovery of any prior payments or
benefits made hereunder, if applicable, unless a court of competent jurisdiction has expressly declared that action to be unlawful. Alternatively, if any court of competent jurisdiction finds that any restriction contained in the Covenants is
unenforceable, and such restriction cannot be amended so as to make it enforceable, 

  
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such finding shall not affect the enforceability of any of the other restrictions contained in the Covenants or other provisions of the Plan. 

(f) All benefits payable to an Eligible Participant are contingent upon and subject to his or her full compliance with the foregoing
obligations during the Severance Period. Accordingly, if the Eligible Participant, at any time, violates any Covenants, any proprietary information or confidentiality obligation to the Company or its affiliates (including
Section 6(c) above), including his or her obligations under the Company’s ECPRA Agreement (or any such similar agreement), or any other obligations under the Plan, (i) any remaining benefits under the Plan will
terminate immediately upon written notice from the Company of such violation and (ii) to the extent the Eligible Participant has received any benefits under the Plan prior to the date of such written notice, the Eligible Participant shall
deliver to the Company, within 30 days, an amount equal to the aggregate of all such benefits. 
 (g) For the avoidance of doubt, any
breach of any of the provisions in this Section 6 shall constitute a material breach by Potential Eligible Participant. Notwithstanding any other provision of the Plan, by becoming entitled to receive any payments or other
benefits under the Plan, Potential Eligible Participant is deemed to have agreed that damages would be an inadequate remedy for the Company in the event of a breach or threatened breach by Potential Eligible Participant of any of Sections
6(b) through 6(d), inclusive. In the event of any such breach or threatened breach, and without relinquishing any other rights or remedies that the Company or its affiliates may have, including but not limited to the repayment by
Potential Eligible Participant of any payments or benefits previously paid to Potential Eligible Participant under the Plan, the Company may, either with or without pursuing any potential damage remedies and without being required to post a bond,
obtain from a court of competent jurisdiction, and enforce, an injunction prohibiting Potential Eligible Participant from violating any of Sections 6(b) through Section 6(d), inclusive, and requiring Potential
Eligible Participant to comply with its provisions to the fullest extent not prohibited by applicable law. The Company may present this Section 6 to any third party with which Potential Eligible Participant may have
accepted employment, or otherwise entered into a business relationship, that the Company contends violates this Section 6, if the Company has reason to believe Potential Eligible Participant has or may have breached a
provision of this Section 6. 
 SECTION 7. CONTINUATION OF EMPLOYMENT BENEFITS. 

(a) Health Plan Benefits Continuation. 

(i) Each Eligible Participant who is enrolled in a health, vision or dental plan sponsored by the Company may be eligible to continue coverage
(the “Continued Coverage”) under such health, vision or dental plan (or to convert to an individual policy) under the Consolidated Omnibus Budget Reconciliation Act of 1985 (“COBRA”). The Company will notify the
Eligible Participant of any such right to continue health coverage at the time of termination. In the event that an Eligible Participant is not eligible to receive Continued Coverage through the Company (either because such Eligible Participant is
not enrolled in any plan sponsored by the Company or because 

  
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such Eligible Participant will be covered by a statutory scheme for continued health, vision or dental coverage that will not be an obligation of the Company), it is understood and agreed that
this Section 7(a) shall not be applicable to such Eligible Participant and, with respect to a Termination Event occurring during a Change in Control Period, he or she shall not be eligible to receive the Continued Coverage
Premiums (as defined below). 
 (ii) Subject to Section 6(f), to the extent set forth in the Benefits Schedules
attached hereto, the Company will pay to an Eligible Participant the before-tax cost of such Eligible Participant’s premiums to cover the Eligible Participant and his or her eligible dependents, if any,
in effect as of the Termination Event (the “Continued Coverage Premiums”) for the period of time set forth in the Benefits Schedules and the Tier applicable to such Eligible Participant. The Continued Coverage Premiums will include
the coverage premium cost of an Eligible Participant’s dependents if, and only to the extent that, such dependents were enrolled in a health, vision or dental plan sponsored by the Company prior to the Eligible Participant’s Termination
Date and such dependents’ premiums under such plans were paid by the Company prior to the Eligible Participant’s Termination Date. No provision of the Plan will affect the continuation coverage rules under COBRA or any other applicable
law. Therefore, the period during which an Eligible Participant must elect to continue the Company’s group medical, vision or dental coverage at his or her own expense under COBRA or other applicable law, the length of time during which
Continued Coverage will be made available to the Eligible Participant, and all other rights and obligations of the Eligible Participant under COBRA or any other applicable law (except the obligation to pay the Continued Coverage Premiums) will be
applied in the same manner that such rules would apply in the absence of the Plan. It is expressly understood and agreed that the Eligible Participant will be solely responsible for the entire payment of premiums required under COBRA or other
applicable law. 
 (b) Other Employee Benefits. All non-health benefits (such as life
insurance and disability coverage) shall terminate as of the Eligible Participant’s Termination Date (except to the extent that any conversion privilege is available thereunder). 

SECTION 8. EXCISE TAXES 
 (a) In
the event that any benefits payable to an Eligible Participant pursuant to the Plan (“Payments”) (i) constitute “parachute payments” within the meaning of Section 280G of the Code, and (ii) but for this
Section 8 would be subject to the excise tax imposed by Section 4999 of the Code, or any comparable successor provisions (the “Excise Tax”), then the Eligible Participant’s payments hereunder
shall be either (i) provided to the Eligible Participant in full, or (ii) provided to the Eligible Participant as to such lesser extent which would result in no portion of such benefits being subject to the Excise Tax, whichever of the
foregoing amounts, when taking into account applicable federal, state, local and foreign income and employment taxes, the Excise Tax, and any other applicable taxes, results in the receipt by the Eligible Participant, on an after-tax basis, of the greatest amount of benefits, notwithstanding that all or some portion of such benefits may be taxable under the Excise Tax. Unless the Company and the Eligible Participant otherwise agree in
writing, any determination required under 

  
 -11- 

  Page
 12
 
  

 
this Section 8 shall be made in writing in good faith by a third-party tax accountant or attorney selected by the Company (the “Tax Professional”). In
the event of a reduction of benefits hereunder, the Tax Professional shall determine which benefits shall be reduced so as to achieve the principle set forth in the preceding sentence. For purposes of making the calculations required by this
Section 8, the Tax Professional may make reasonable assumptions and approximations concerning applicable taxes and may rely on reasonable, good faith interpretations concerning the application of the Code and other
applicable legal authority. The Company and the applicable Eligible Participant shall furnish to the Tax Professional such information and documents as the Tax Professional may reasonably request in order to make a determination under this
Section 8. The Company shall bear all costs the Tax Professional may incur in connection with any calculations contemplated by this Section 8. 

(b) If, notwithstanding any reduction described in Section 8(a), the IRS determines that an Eligible
Participant is liable for the Excise Tax as a result of the receipt of any payments made pursuant to the Plan, then the Eligible Participant shall be obligated to pay back to the Company, within 30 days after a final IRS determination or in the
event that the Eligible Participant challenges the final IRS determination, a final judicial determination, a portion of the Payments equal to the Repayment Amount. The “Repayment Amount” means the smallest such amount, if any, as
shall be required to be paid to the Company so that the Eligible Participant’s net after-tax proceeds with respect to the Payments (after taking into account the payment of the Excise Tax and all other
applicable taxes imposed on such benefits) shall be maximized. The Repayment Amount shall be zero if a Repayment Amount of more than zero would not result in the Eligible Participant’s net after-tax
proceeds with respect to the Payments being maximized. If the Excise Tax is not eliminated pursuant to this Section 8(b), the Eligible Participant shall pay the Excise Tax. If, after the Payments have been made to the
Eligible Participant, it is established that the Payments made to, or provided for the benefit of, the Eligible Participant are less than the maximum amount determined under Section 8(a) above (an
“Underpayment”), then the Company shall pay an amount equal to the Underpayment to the Eligible Participant on the later of (i) 20 days after such determination or resolution and (ii) the time period such Payment would
otherwise have been paid or provided to the Eligible Participant under the Plan. 
 (c) Notwithstanding any other provision of this
Section 8, if (i) there is a reduction in the payments to an Eligible Participant as described in this Section 8, (ii) the IRS later determines that the Eligible Participant is liable for
the Excise Tax, the payment of which would result in the maximization of the Eligible Participant’s net after-tax proceeds (calculated as if the Eligible Participant’s benefits had not previously
been reduced), and (iii) the Eligible Participant pays the Excise Tax, then the Company shall pay to the Eligible Participant those payments which were reduced pursuant to this Section 8 as soon as administratively
possible after the Eligible Participant pays the Excise Tax so that the Eligible Participant’s net after-tax proceeds with respect to the payment of the Payments are maximized. 

  
 -12- 

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 SECTION 9. RIGHT TO INTERPRET PLAN; AMEND AND TERMINATE; OTHER ARRANGEMENTS; BINDING NATURE OF PLAN.

 (a) Exclusive Discretion. The “Plan Administrator” shall be the Compensation Committee of the Board.
The Plan Administrator shall have the exclusive discretion and authority to establish rules, forms, and procedures for the administration of the Plan, and to construe and interpret the Plan and to decide any and all questions of fact,
interpretation, definition, computation or administration arising in connection with the operation of the Plan, including, but not limited to, the eligibility to participate in the Plan, the designation of the Tier applicable to each Potential
Eligible Participant, the amount of benefits paid under the Plan, the timing of payments under the Plan and the scope and applicability of the covenants contained in the Release and Covenant Documents. The rules, interpretations, computations and
other actions of the Plan Administrator shall be binding and conclusive on all Persons. For decisions made by the Plan Administrator that do not affect benefits payable under the Plan on account of the occurrence of a Termination Event during the
Change in Control Period, the Plan Administrator’s decisions shall not be subject to review unless they are found to be arbitrary and capricious. For decisions made by the Plan Administrator prior to the occurrence of a Change in Control that
do affect benefits payable under the Plan on account of the occurrence of a Termination Event during the Change in Control Period, the Plan Administrator’s decisions shall not be subject to review unless they are found to be unreasonable or not
to have been made in good faith. For decisions made by the Plan Administrator at or after the occurrence of a Change in Control that affect benefits payable under the Plan on account of the occurrence of a Termination Event during the Change in
Control Period, the Plan Administrator’s decisions shall be subject to review. As used in this Section 9(a), “review” shall mean review as provided by applicable law; further, nothing in this
Section 9(a) is intended to abridge any of the rights under Section 12 of the Plan. Except as provided in Section 9(b)(i), the Plan Administrator may appoint one or more
individuals and delegate such of its powers and duties as it deems desirable to any such individual(s), in which case every reference herein made to the Plan Administrator shall be deemed to mean or include the appointed individual(s) as to matters
within the scope of their delegated authority. 
 (b) Term Of Plan; Termination or Suspension; Amendment; Binding Nature Of Plan. 

(i) The Board or the Plan Administrator may by written resolution terminate or suspend the Plan at any time and for any reason or no reason,
which termination or suspension, as applicable, shall become effective at the time set forth in such resolutions, provided, however, that no such termination or suspension shall effect the Company’s obligation to complete the delivery of
benefits hereunder to any Potential Eligible Participant who becomes an Eligible Participant prior to the effective time of such termination or suspension; and further provided, that during the Change in Control Period, the Plan shall not be
terminated or suspended. Notwithstanding any other provision of the Plan to the contrary, including Section 9(a), the Plan Administrator may not delegate its authority to suspend or terminate the Plan. 

  
 -13- 

  Page
 14
 
  

 (ii) The Company (including, for the avoidance of doubt, by written resolution or the Board
or the Plan Administrator) reserves the right to amend the Plan or the benefits provided hereunder at any time and in any manner (including, for avoidance of doubt, removing one or more employees from treatment as a Potential Eligible Participant);
provided, however, that no such amendment shall materially adversely affect the interests or rights of any Eligible Participant whose Termination Date has occurred prior to amendment of the Plan; and further provided, that during the
Change in Control Period, the Plan shall not be amended in a manner that causes any Potential Eligible Participant to have benefits reduced without the written consent of the Potential Eligible Participant or Potential Eligible Participants so
affected. Subject to the foregoing rights of the Company set forth in this Section 9(b), the Plan establishes and vests in each Eligible Participant a contractual right to the benefits to which such Eligible Participant is
entitled hereunder, enforceable by the Eligible Participant against the Company. 
 (iii) Any action amending, suspending or terminating the
Plan shall be in writing and approved by the Plan Administrator or its delegate, except to the extent that the Plan specifies that such action shall be taken by the Board or the Board determines to take such action. 

(c) Binding Effect On Successor To Company. The Plan shall be binding upon any successor or assignee, whether direct or indirect,
by purchase, merger, consolidation or otherwise, to all or substantially all the business or assets of the Company, or upon any successor to the Company as the result of a Change in Control, and any such successor or assignee shall be required to
perform the Company’s obligations under the Plan, in the same manner and to the same extent that the Company would be required to perform if no such succession or assignment or Change in Control had taken place. In such event, the term
“Company,” as used in the Plan, shall mean the Company as hereinafter defined and any successor or assignee as described above which by reason hereof becomes bound by the terms and provisions of the Plan. 

SECTION 10. NO IMPLIED EMPLOYMENT CONTRACT. 

The Plan shall not be deemed (a) to give any employee or other person any right to be retained in the employ of the Company or any
affiliate thereof or (b) to interfere with the right of the Company or any such affiliate to discharge any employee or other person at any time and for any reason, which right is hereby reserved. 

SECTION 11. LEGAL CONSTRUCTION. 
 The Plan
is intended to be governed by and shall be construed in accordance with the Employee Retirement Income Security Act of 1974, as amended (“ERISA”) and, to the extent not preempted by ERISA, the laws of the State of Delaware with
respect to those Eligible Participants domiciled in the United States. The Plan is intended to be (a) an employee welfare plan as defined in Section 3(1) of ERISA and (b) a “top-hat”
plan maintained for the benefit of a select group of management or highly compensated employees of the Company. 

  
 -14- 

  Page
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 SECTION 12. CLAIMS, INQUIRIES AND APPEALS. 

(a) Applications For Benefits And Inquiries. Any application for benefits, inquiries about the Plan or inquiries about present or
future rights under the Plan must be submitted to the Plan Administrator in writing. The name and address of the Plan Administrator is: 
 The
Compensation Committee 
 of the Board of Directors of 

Progenity, Inc. 
 ATTN: Clarke
Neumann 
 4330 La Jolla Village Drive, Suite 200 

San Diego, California 92122 

(b) Denial Of Claims. In the event that any application for benefits is denied in whole or in part, the Plan Administrator must
notify the applicant, in writing, of the denial of the application, and of the applicant’s right to review the denial. The written notice of denial will be set forth in a manner designed to be understood by the employee, and will include
specific reasons for the denial, specific references to the provision of the Plan upon which the denial is based, a description of any information or material that the Plan Administrator needs to complete the review and an explanation of the
Plan’s review procedure. 
 This written notice will be given to the employee within 90 days after the Plan Administrator receives the
application, unless special circumstances require an extension of time, in which case, the Plan Administrator has up to an additional 90 days for processing the application. If an extension of time for processing is required, written notice of the
extension will be furnished to the applicant before the end of the initial 90-day period. 
 This
notice of extension will describe the special circumstances necessitating the additional time and the date by which the Plan Administrator is to render its decision on the application. If written notice of denial of the application for benefits is
not furnished within the specified time, the application shall be deemed to be denied. The applicant will then be permitted to appeal the denial in accordance with the Review Procedure described below. 

(c) Request For A Review. Any person (or that person’s authorized representative) for whom an application for benefits is
denied (or deemed denied), in whole or in part, may appeal the denial by submitting a request for a review to the Plan Administrator within 60 days after the application is denied (or deemed denied). The Plan Administrator will give the applicant
(or his or her representative) an opportunity to review pertinent documents in preparing a request for a review. A request for a review shall be in writing and shall be addressed to: 

Progenity, Inc. 
 Plan Administrator
for the Severance Plan 

  
 -15- 

  Page
 16
 
  

 ATTN: Clarke Neumann 

4330 La Jolla Village Drive, Suite 200 

San Diego, California 92122 
 A request for review
must set forth all of the grounds on which it is based, all facts in support of the request and any other matters that the applicant feels are pertinent. The Plan Administrator may require the applicant to submit additional facts, documents or other
material as it may find necessary or appropriate in making its review. 
 (d) Decision On Review. The Plan Administrator will
act on each request for review within 60 days after receipt of the request, unless special circumstances require an extension of time (not to exceed an additional 60 days), for processing the request for a review. If an extension for review is
required, written notice of the extension will be furnished to the applicant within the initial 60-day period. The Plan Administrator will give prompt, written notice of its decision to the applicant. In the
event that the Plan Administrator confirms the denial of the application for benefits in whole or in part, the notice will outline, in a manner calculated to be understood by the applicant, the specific provisions of the Plan upon which the decision
is based. If written notice of the Plan Administrator’s decision is not given to the applicant within the time prescribed in this Subsection (d), the application will be deemed denied on review. 

(e) Rules And Procedures. The Plan Administrator will establish rules and procedures, consistent with the Plan and with ERISA, as
necessary and appropriate in carrying out its responsibilities in reviewing benefit claims. The Plan Administrator may require an applicant who wishes to submit additional information in connection with an appeal from the denial (or deemed denial)
of benefits to do so at the applicant’s own expense. 
 (f) Exhaustion Of Remedies. No legal action for benefits under the
Plan may be brought until the claimant (i) has submitted a written application for benefits in accordance with the procedures described by Section 12(a) above, (ii) has been notified by the Plan Administrator that
the application is denied (or the application is deemed denied due to the Plan Administrator’s failure to act on it within the established time period), (iii) has filed a written request for a review of the application in accordance with
the appeal procedure described in Section 12(c) above and (iv) has been notified in writing that the Plan Administrator has denied the appeal (or the appeal is deemed to be denied due to the Plan Administrator’s
failure to take any action on the claim within the time prescribed by Section 12(d) above). 
 SECTION 13. BASIS OF PAYMENTS TO
AND FROM PLAN. 
 All benefits under the Plan shall be paid by the Company. The Plan shall be unfunded, and benefits hereunder shall be
paid only from the general assets of the Company. 

  
 -16- 

  Page
 17
 
  

 SECTION 14. OTHER PLAN INFORMATION. 

(a) Employer And Plan Identification Numbers. The Employer Identification Number assigned to the Company (which is the “Plan
Sponsor” as that term is used in ERISA) by the Internal Revenue Service is 27-3950390. The Plan Number assigned to the Plan by the Plan Sponsor pursuant to the instructions of the Internal Revenue Service
is 502. 
 (b) Ending Date For Plan’s Fiscal Year. The date of the end of the fiscal year for the purpose of maintaining
the Plan’s records is December 31. 
 (c) Agent For The Service Of Legal Process. The agent for the service of legal
process with respect to the Plan is the General Counsel, Progenity, Inc., 4330 La Jolla Village Drive, Suite 200, San Diego, California 92122. The service of legal process may also be made on the Plan by serving the Plan Administrator. 

(d) Plan Sponsor And Administrator. The “Plan Sponsor” of the Plan is Progenity, Inc., and the “Plan
Administrator” of the Plan is the Compensation Committee of the Board. Each of the Plan Sponsor and the Plan Administrator can be reached by contacting Clarke Neumann in writing at 4330 La Jolla Village Drive, Suite 200, San Diego, California
92122, and by telephone at (855) 293-2639. The Plan Administrator is the named fiduciary charged with the responsibility for administering the Plan. 

SECTION 15. STATEMENT OF ERISA RIGHTS. 

This statement of ERISA rights is required by United States federal law and regulation, and follows the model disclosure set forth in federal
regulations. 
 Participants in the Plan (which is a welfare benefit plan sponsored by Progenity, Inc.) are entitled to certain rights and
protections under ERISA if the participant is employed in the United States. If you are an Eligible Participant employed in the United States, you are considered a participant in the Plan and, under ERISA, you are entitled to: 

(a) Examine, without charge, at the Plan Administrator’s office and at other specified locations, such as work sites, all Plan
documents and copies of all documents filed by the Plan with the U.S. Department of Labor, such as detailed annual reports; 
 (b)
Obtain copies of all Plan documents and Plan information upon written request to the Plan Administrator. The Plan Administrator may make a reasonable charge for the copies; 

(c) Receive a summary of the Plan’s annual financial report, in the case of a plan which is required to file an annual financial
report with the Department of Labor. (Generally, all pension plans and welfare plans with 100 or more participants must file these annual reports.) 

  
 -17- 

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 18
 
  

 In addition to creating rights for Plan participants, ERISA imposes duties upon the people
responsible for the operation of the employee benefit plan. The people who operate the Plan, called “fiduciaries” of the Plan, have a duty to do so prudently and in the interest of you and other Plan participants and beneficiaries. 

No one, including your employer or any other person, may fire you or otherwise discriminate against you in any way to prevent you from
obtaining a Plan benefit or exercising your rights under ERISA. If your claim for a Plan benefit is denied in whole or in part, you must receive a written explanation of the reason for the denial. You have the right to have the Plan Administrator
review and reconsider your claim. 
 Under ERISA, there are steps you can take to enforce the above rights. For instance, if you request
materials from the Plan and do not receive them within 30 days, you may file suit in a federal court. In such a case, the court may require the Plan Administrator to provide the materials and pay you up to $110 a day until you receive the materials,
unless the materials were not sent because of reasons beyond the control of the Plan Administrator. If you have a claim for benefits that is denied or ignored, in whole or in part, you may file suit in a state or federal court. If it should happen
that the Plan fiduciaries misuse the Plan’s money, or if you are discriminated against for asserting your rights, you may seek assistance from the U.S. Department of Labor, or you may file suit in a federal court. The court will decide who
should pay court costs and legal fees. If you are successful, the court may order the person you have sued to pay these costs and fees. If you lose, the court may order you to pay these costs and fees, for example, if it finds your claim is
frivolous. 
 If you have any questions about the Plan, you should contact the Plan Administrator. If you have any questions, about your
rights under ERISA, you should contact the nearest area office of the Employee Benefits Security Administration, U.S. Department of Labor, listed in your telephone directory or the Division of Technical Assistance and Inquiries, Employee Benefits
Security Administration, U.S. Department of Labor, 200 Constitution Avenue N.W., Washington, D.C. 20210. You may also obtain certain publications about your rights and responsibilities under ERISA by calling the publications hotline of the Employee
Benefits Security Administration. 
 SECTION 16. EFFECT OF SECTION 409A OF THE CODE 

The Plan is intended to comply with all applicable law, including Section 409A of the Code. A termination of employment shall not be
deemed to have occurred for purposes of any provision of the Plan providing for the payment of any amount or benefit that is considered deferred compensation under Section 409A of the Code upon or following a termination of employment unless
such termination of employment is also a “separation from service” within the meaning of Section 409A of the Code. If an Eligible Participant is deemed on the Termination Date to be a “specified employee” (as such term is
defined under Section 409A of the Code), then with regard to any payment or the provision of any benefit that is considered deferred compensation under Section 409A of the Code payable on account of a “separation from service,”
to the extent required to avoid any taxes imposed 

  
 -18- 

  Page
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under Section 409A(a)(1) of the Code, such payment or benefit shall be made or provided at the date which is no more than 15 days following the earlier of (a) the expiration of the six-month period measured from the date of such “separation from service” of such Eligible Participant, and (b) the date of such Eligible Participant’s death. 

END OF PLAN DOCUMENT 

  
 -19- 

 SCHEDULE A 

Potential Eligible Participants employed in the United States: 

Progenity, Inc., a Delaware corporation Delaware 

Mattison Pathology, LLP dba Avero Diagnostics 

  
 -1- 

 BENEFIT SCHEDULES 

FOR THE 
 PROGENITY, INC.

 SEVERANCE PLAN 
 The following
benefits schedules set forth the benefits payable to an Eligible Participant. The benefits schedules may be disclosed in public filings for those Potential Eligible Participants who currently are, or are foreseeable to become, “named executive
officers,” as defined in Item 402 of Regulation S-K and the other applicable rules and regulations promulgated by the Securities and Exchange Commission. The amount of benefits payable is dependent upon
the “Tier” assigned to the Eligible Participant and whether the involuntary Termination Event occurs during a Change in Control Period, as more particularly described in the Plan. 

The Plan Administrator shall determine in which “Tier” a Potential Eligible Participant shall be placed for purposes of receiving severance benefits
under the Plan. The Plan Administrator’s determination shall be final and shall be binding and conclusive on all Persons. The Plan Administrator retains the right to designate a different Tier applicable to a Potential Eligible Participant
prior to the date of the Termination Event and/or the occurrence of a Change in Control, except as expressly restricted by the Plan in connection with the occurrence of a Change in Control. 

  
 -1- 

 BENEFITS SCHEDULES 

FOR THE 
 PROGENITY, INC.

 SEVERANCE PLAN 
  

					
	Tier:	 	1	 	 Potential Eligible Participant: Chief Executive Officer

			
	Location:	 	U.S.	 	

 Benefits Payable in the Event of a Termination Event (involuntary termination): 

 

			
	WITHOUT A CHANGE IN CONTROL
	Base	  	12 months of Pay
		
	Benefits	  	Continued Coverage Premiums for 12 months; paid in monthly installments (but no payment required prior to the Payment Confirmation Date). Any installments delayed on account of the application of the preceding sentence shall be paid
as part of the first installment.
		
	Payout Schedule	  	Pay (Base only) to be paid in equal semi-monthly installments for 12 months following the Termination Date, but not to commence prior to 30 business days after the Payment Confirmation Date (subject to Section 5 of the Plan and
Section 409A of the Code). Any installments delayed on account of the application of the preceding sentence shall be paid as part of the first installment.

  

			
	 CHANGE IN CONTROL TERMINATION EVENT

Note: No enhanced benefits due to a Termination Event occurring on account of a Change in
Control Termination Event shall be paid prior to
the effective date of a Change in Control.

		
	Base	  	24 months of Pay
		
	Bonus	  	24 months of Average Annual Bonus
		
	Benefits	  	Continued Coverage Premiums for 24 months (or if shorter, the maximum period allowable under COBRA); paid in monthly installments (but no payment required prior to the Payment Confirmation Date). Any installments delayed on account
of the application of the preceding sentence shall be paid as part of the first installment.
		
	Equity	  	All unvested equity-based awards that are subject solely to time-based vesting conditions and that are outstanding as of the Termination Date shall immediately accelerate in full and all unvested equity-based awards that are subject
to performance-based vesting conditions and that are outstanding as of the Termination Date shall vest, if at all, based on actual performance for the portion of the performance period ending shortly prior to the occurrence of the Change in Control
as if such partial performance period were the entire performance period.

  
 -1- 

 Page 2 
  

			
	Payout Schedule	  	100% of Base and Bonus is payable in a lump sum within 30 business days after the Payment Confirmation Date (subject to Section 5 of the Plan and Section 409A of the Code).

  
 -2- 

 BENEFITS SCHEDULES 

FOR THE 
 PROGENITY, INC.
SEVERANCE PLAN 
  

					
			
	 Tier:
  

Location:
	 	 2
  

U.S.
	 	 Potential Eligible Participants: Determined by the Plan Administrator

 Benefits Payable in the Event of a Termination Event (involuntary termination): 

 

			
	WITHOUT A CHANGE IN CONTROL
	Base	  	9 months of Pay
		
	Benefits	  	Continued Coverage Premiums for 9 months; paid in monthly installments (but no payment required prior to the Payment Confirmation Date). Any installments delayed on account of the application of the preceding sentence shall be paid
as part of the first installment.
		
	Payout Schedule	  	Pay (Base only) to be paid in equal semi-monthly installments for 9 months following the Termination Date, but not to commence prior to 30 business days after the Payment Confirmation Date (subject to Section 5 of the Plan and
Section 409A of the Code). Any installments delayed on account of the application of the preceding sentence shall be paid as part of the first installment.

  

			
	 CHANGE IN CONTROL TERMINATION EVENT

Note: No enhanced benefits due to a Change in Control Termination Event shall be paid prior to the effective date of a Change in
Control.

		
	Base	  	18 months of Pay
		
	Bonus	  	18 months of Average Annual Bonus
		
	Benefits	  	Continued Coverage Premiums for 18 months; paid in monthly installments (but no payment required prior to the Payment Confirmation Date). Any installments delayed on account of the application of the preceding sentence shall be paid
as part of the first installment.
		
	Equity	  	All unvested equity-based awards that are subject solely to time-based vesting conditions and that are outstanding as of the Termination Date shall immediately accelerate in full and all unvested equity-based awards that are subject
to performance-based vesting conditions and that are outstanding as of the Termination Date shall vest, if at all, based on actual performance for the portion of the performance period ending shortly prior to the occurrence of the Change in Control
as if such partial performance period were the entire performance period.

  
 -1- 

 Page 2 
  

			
	Payout Schedule	  	100% of Base and Bonus are payable in a lump sum within 30 business days after the Payment Confirmation Date (subject to Section 5 of the Plan and Section 409A of the Code).

  
 -2- 

 BENEFITS SCHEDULES 

FOR THE 
 PROGENITY, INC.
SEVERANCE PLAN 
  

					
	 Tier:
  

Location:
	 	 3
  

U.S.
	 	 Potential Eligible Participants: Determined by the Plan Administrator

 

 Benefits Payable in the Event of a Termination Event (involuntary termination): 

 

			
	WITHOUT A CHANGE IN CONTROL
	Base	  	6 months of Pay
		
	Benefits	  	Continued Coverage Premiums for 6 months; paid in monthly installments (but no payment required prior to the Payment Confirmation Date). Any installments delayed on account of the application of the preceding sentence shall be paid
as part of the first installment.
		
	Payout Schedule	  	Pay (Base only) to be paid in equal semi-monthly installments for 6 months following the Termination Date, but not to commence prior to 30 business days after the Payment Confirmation Date (subject to Section 5 of the Plan and
Section 409A of the Code). Any installments delayed on account of the application of the preceding sentence shall be paid as part of the first installment.

  

			
	 CHANGE IN CONTROL PERIOD TERMINATION EVENT

Note: No enhanced benefits due to a Change in Control Termination Event shall be paid prior to the effective date of a Change in
Control.

		
	Base	  	12 months of Pay
		
	Bonus	  	12 months of Average Annual Bonus
		
	Benefits	  	Continued Coverage Premiums for 12 months; paid in monthly installments (but no payment required prior to the Payment Confirmation Date). Any installments delayed on account of the application of the preceding sentence shall be paid
as part of the first installment.
		
	Equity	  	All unvested equity-based awards that are subject solely to time-based vesting conditions and that are outstanding as of the Termination Date shall immediately accelerate in full and all unvested equity-based awards that are subject
to performance-based vesting conditions and that are outstanding as of the Termination Date shall vest, if at all, based on actual performance for the portion of the performance period ending shortly prior to the occurrence of the Change in Control
as if such partial performance period were the entire performance period.

  
 -1- 

 Page 2 
  

			
	Payout Schedule	  	100% of Base and Bonus are payable in a lump sum within 30 business days after the Payment Confirmation Date (subject to Section 5 of the Plan and Section 409A of the Code).

  
 -2-

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