Document:

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                                                                     Exhibit 4.1

                              Amended and Restated
                          Registration Rights Agreement

     This Agreement is entered into as of July 26, 2002 by Stericycle, Inc., a
Delaware corporation (the "Company"), and the Persons whose names are set forth
on the attached Schedule I (collectively, the "Investors").

     A. The Company and the Investors are the parties currently bound by that
certain Registration Rights Agreement, dated as of November 12, 1999 (the "1999
Registration Rights Agreement"), which was entered into at the closing of that
certain Amended and Restated Series A Convertible Preferred Stock Purchase
Agreement, dated September 26, 1999 (the "Purchase Agreement"), pursuant to the
terms and conditions of which the Company issued and sold to the purchasers, and
the purchasers purchased from the Company, 75,000 shares of the Company's Series
A Convertible Preferred Stock (the "Preferred Shares").

     B. The Company and the Investors desire to amend and restate the 1999
Registration Rights Agreement as set out in this Agreement.

     C. This Agreement is entered into pursuant to the Amendment and Waiver
Agreement, dated as of the same date as this Agreement (the "Waiver Agreement"),
entered into by the Company and the Investors. The execution and delivery of
this Agreement by the Company and the Investors is a condition of the Waiver
Agreement becoming effective.

     The Company and the Investors agree that the 1999 Registration Rights
Agreement is amended and restated as follows, effective as of June 1, 2002:

     Capitalized terms which are used in this Agreement without being defined
have the same meanings that they are given in the Purchase Agreement. Certain
capitalized terms used in this Agreement are defined in the attached Schedule A.

     1.  Demand Registrations.

     1A. General.

     Holders of a majority of a Group's Registrable Securities then outstanding
may request, at any time after August 29, 2002, registration under the
Securities Act of all or any portion of their Registrable Securities (a "Demand
Registration"). Each Group shall be limited to two Demand Registrations, (i)
each of which may be a shelf registration (a "Shelf Registration") pursuant to
Rule 415 under the Securities Act (or any successor rule) or (ii) one of which
may be a Shelf Registration and the other of which may be a firm commitment
underwritten public offering (an "Underwritten Registration"). Each request for
a Demand Registration shall specify whether the request is for a Shelf
Registration or an Underwritten Registration. In regard to

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Demand Registrations:

          (1) Each request for an Underwritten Registration shall specify the
     approximate number of Registrable Securities requested to be registered.
     Within 10 days after receipt of any request for an Underwritten
     Registration, the Company shall give written notice of the requested
     registration to (i) all other holders of Registrable Securities who are
     members of the same Group (the "Requesting Group") and (ii) all holders who
     are members of the other Group (the "Other Group"), and shall include in
     the registration all Registrable Securities with respect to which the
     Company has received written requests for inclusion within 15 days after
     receipt of the Company's notice. The inclusion in the registration of
     Registrable Securities held by members of the Other Group shall not be
     counted as one of the Other Group's two permitted Demand Registrations.

          (2) A Demand Registration shall not be counted as one of the
     Requesting Group's two permitted Demand Registrations unless (i) it has
     become effective and (ii) in the case of an Underwritten Registration, the
     Persons making the request are able to register and sell at least 75% of
     the Registrable Securities included in the registration.

          (3) The Company shall pay all Registration Expenses in connection with
     any Demand Registration whether or not it is counted as one of the
     Requesting Group's two permitted Demand Registrations.

          (4) Demand Registrations shall be on Form S-2 or Form S-3 or any
     similar short-form registration statement, if available.

          (5) In the case of any Underwritten Registration, the Company shall
     have the right to select the managing underwriter in connection with the
     offering, subject to the approval of a majority of the holders of the
     Registrable Securities requesting registration, and holders of a majority
     of the Registrable Securities requesting registration shall have the right
     to select a co-managing underwriter, subject to the Company's approval.

     1B. Limit on Registrable Securities.

     In the case of any Underwritten Registration, if the managing underwriters
advise the Company in writing that in their opinion the number of Registrable
Securities requested to be included in the offering exceeds the number of
Registrable Securities that can be sold without adversely affecting the
marketability of the offering, the Company shall include in the registration the
number of Registrable Securities requested to be included which in the opinion
of the underwriters can be sold without adversely affecting the marketability of
the offering (the "Approved Limit"). Any reduction to the Approved Limit in the
number of Registrable Securities included in the registration shall be made pro
rata among the requesting holders on the basis of the number of Registrable
Securities owned by each holder.

                                       -2-

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     1C. Restrictions.

     The Company shall not be obligated to effect any request for an
Underwritten Registration within 180 days after the effective date of a previous
Underwritten Registration or a previous registration in which holders of
Registrable Securities were given piggyback rights pursuant to Section 2. Except
in the case of the first request for a Demand Registration (if the request is
made after August 29, 2002 and if the request is for an Underwritten
Registration), the Company may postpone for up to 180 days the filing or the
effectiveness of a registration statement for an Underwritten Registration if
the Company's board of directors in good faith reasonably determines that the
Underwritten Registration would reasonably be expected to have a material
adverse effect on any proposal or plan by the Company to engage in any
acquisition of assets (other than in the ordinary course of business) or any
merger, consolidation, tender offer, reorganization or similar transaction. In
this event, the holders of Registrable Securities initially requesting the
Underwritten Registration shall be entitled to withdraw their request. If their
request is withdrawn, the Underwritten Registration shall not count as one of
the Requesting Group's two permitted Demand Registrations, and the Company shall
pay all Registration Expenses in connection with the registration. In respect of
each Group, the Company may delay an Underwritten Registration pursuant to this
Section 1C only once in any 12-month period.

     1D. Shelf Registration.

     In the event of a request for a Shelf Registration, the Company shall
promptly prepare and file a shelf registration statement (as amended and
supplemented from time to time, the "Shelf Registration Statement") in
accordance with Rule 415 under the Securities Act (or any similar rule that may
be adopted by the Securities and Exchange Commission), and cause it to be
declared effective as soon as reasonably practicable (and in any event within 90
days) after such request and will keep such Shelf Registration Statement
continuously effective and in compliance with the Security Act and usable for
resale or other disposition of the covered Registrable Securities, subject to
clauses (1) and (2) below, for the period (the "Effective Period") commencing on
the date on which the Securities and Exchange Commission declares such Shelf
Registration Statement effective and ending on the earlier of (x) the first
anniversary date of the date such Shelf Registration Statement is declared
effective (or, in event the Company has exercised its right under clause (1)
below to refuse use of the Shelf Registration for a Delay Period, the
eighteen-month anniversary date of the date such Shelf Registration Statement is
declared effective) and (y) the first date on which there are no longer any
Registrable Securities. The Effective Period shall be automatically extended by
the number of days that the second Delay Period, if any, is in effect during the
final thirty days of the Effective Period prior to any such extension. In regard
to the Shelf Registration Statement:

          (1) Except in the case of the first request for a Demand Registration
     (if the request is made after August 29, 2002 and if the request is for a
     Shelf Registration), the Company shall have the right to refuse use of an
     effective Shelf Registration Statement (a "Delay Period") for a length of
     time not to exceed 45 days if the Company's board of directors reasonably
     determines, with respect to the advisability (as determined in good faith)
     of deferring public disclosure of material corporate developments, that use
     of the shelf

                                       -3-

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     Registration Statement and the disclosure required to be made therein would
     not be in the best interests of the Company at such time; provided,
     however, that there shall not be more than two Delay Periods during the
     Effective Period. The Company shall use reasonable efforts to minimize the
     length of any Delay Period and shall provide prompt written notice to the
     holders of Registrable Securities of the beginning and end of each Delay
     period.

          (2) The Company shall promptly notify the holders of Registrable
     Securities, at any time when a prospectus relating to the sale of the
     Registrable Securities is required by law to be delivered in connection
     with sales by an underwriter or dealer, of the occurrence of any event
     requiring the preparation of a supplement or amendment to such prospectus
     so that, as thereafter delivered to the purchasers of such Registrable
     Securities, such prospectus will not contain an untrue statement of a
     material fact or omit to state any material fact required to be stated
     therein or necessary to make the statements therein, in the light of the
     circumstances under which they were made, not misleading and shall (subject
     to any Delay Period) promptly make available to holders of Registrable
     Securities and to the underwriters any such supplement or amendment.
     Holders of Registrable Securities agree that, upon receipt of any notice
     from the Company of the occurrence of any event of the kind described in
     the preceding sentence, holders of Registrable Securities will forthwith
     discontinue the offer and sale of Registrable Securities pursuant to the
     Shelf Registration Statement until receipt by holders of Registrable
     Securities and the underwriters of the copies of such supplemented or
     amended prospectus.

     2.  Piggyback Registrations.

     2A. Right To Piggyback.

     Whenever the Company proposes to register any of its securities under the
Securities Act (whether or not pursuant to a Demand Registration) and the
registration form to be used may be used for the registration of Registrable
Securities (a "Piggyback Registration"), the Company shall give prompt written
notice to all holders of Registrable Securities of its intention to effect such
a registration and shall include in the registration all Registrable Securities
with respect to which the Company has received written requests for inclusion
within 20 days after receipt of the Company's notice. Holders of Registrable
Securities shall be entitled to unlimited Piggyback Registrations for their
Registrable Securities.

     2B. Piggyback Expenses.

     The Registration Expenses of the holders of Registrable Securities shall be
paid by the Company in all Piggyback Registrations.

     2C. Priority on Primary Registrations.

     If a Piggyback Registration is an underwritten primary registration on
behalf of the

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Company, and the managing underwriters advise the Company in writing that in
their opinion the number of securities requested to be included in the
registration exceeds the number that can be sold without adversely affecting the
marketability of the offering, the Company shall include in the registration (i)
first, the securities that the Company proposes to sell, (ii) second, the
Registrable Securities requested to be included in the registration, pro rata
among the holders of the Registrable Securities on the basis of the number of
Registrable Securities owned by each holder, and (iii) third, any other
securities requested to be included in the registration.

     2D. Priority on Secondary Registrations.

     If a Piggyback Registration is an underwritten secondary registration on
behalf of holders of the Company's securities, and the managing underwriters
advise the Company in writing that in their opinion the number of securities
requested to be included in the registration exceeds the number that can be sold
without adversely affecting the marketability of the offering, the Company shall
include in the registration (i) first, the Registrable Securities requested to
be included in the registration, pro rata among the holders of the Registrable
Securities on the basis of the number of Registrable Securities owned by each
holder, and (ii) second, the other securities requested to be included in the
registration.

     2E. Other Registrations.

     If the Company has previously filed a registration statement with respect
to Registrable Securities pursuant to Section 1 or pursuant to this Section 2,
and if the previous registration has not been withdrawn or abandoned, the
Company shall not file or cause to be effected any other registration of any of
its equity securities or securities convertible or exchangeable into or
exercisable for its equity securities under the Securities Act (except on Form
S-8 or any successor form), whether on its own behalf or at the request of any
holder or holders of its securities, until a period of at least 180 days has
elapsed from the effective date of the previous registration.

     3.  Holdback Agreements.

     3A. Holders of Registrable Securities.

     Each holder of Registrable Securities shall not effect any public sale or
distribution (including sales pursuant to Rule 144) of equity securities of the
Company, or any securities convertible into or exchangeable or exercisable for
equity securities of the Company, during the 30 days prior to and the 120-day
period (or such lesser period as the managing underwriters may agree to)
beginning on the effective date of any Underwritten Registration in which
Registrable Shares of the holder's Group are included or any underwritten
Piggyback Registration in which Registrable Securities of the holder's Group are
included (except as part of such Underwritten Registration or underwritten
Piggyback Registration), unless the underwriters managing the offering otherwise
agree.

                                       -5-

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     3B.  Company.

     The Company (i) shall not effect any public sale or distribution of its
equity securities, or any securities convertible into or exchangeable or
exercisable for such securities, during such period prior to and following the
effective date of any Underwritten Registration or any underwritten Piggyback
Registration as the Company and the underwriters managing the offering may
agree.

     4.   Registration Procedures.

     Whenever holders of Registrable Securities have requested that any
Registrable Securities be registered pursuant to this Agreement, the Company
shall use its reasonable best efforts to effect the registration and the sale of
the Registrable Securities in accordance with the intended method of
disposition, In this regard, the Company shall:

          (1) prepare and file with the Securities and Exchange Commission a
     registration statement with respect to such Registrable Securities and use
     its reasonable best efforts to cause the registration statement to become
     effective;

          (2) notify each holder of Registrable Securities of the effectiveness
     of each registration statement filed under this Agreement and prepare and
     file with the Securities and Exchange Commission any amendments and
     supplements to the registration statement and the prospectus that may be
     necessary to keep the registration statement effective for a period of not
     less than 180 days (in the case of an Underwritten Registration or an
     underwritten Piggyback Registration) or for the Effective Period, subject
     to clauses (1) and (2) of Section 1.D (in the case of a Shelf
     Registration), and comply with the provisions of the Securities Act with
     respect to the disposition of all securities covered by the registration
     statement during the applicable period in accordance with the intended
     methods of disposition by the sellers described in the registration
     statement;

          (3) furnish to each seller of Registrable Securities the number of
     copies of the registration statement, each amendment and supplement, the
     prospectus included in the registration statement ( including each
     preliminary prospectus) and any other documents that each seller may
     reasonably request in order to facilitate the disposition of the seller's
     Registrable Securities;

          (4) use its best efforts to register or qualify the Registrable
     Securities under such other securities or blue sky laws of such
     jurisdictions as any seller reasonably requests and do any and all other
     acts and things which may be reasonably necessary or advisable to enable
     the seller to consummate the disposition in those jurisdictions of the
     Registrable Securities owned by the seller (but the Company shall not be
     required to (i) qualify generally to do business in any jurisdiction where
     it would not otherwise be required to qualify but for this subparagraph,
     (ii) subject itself to taxation in any such jurisdiction or (iii) consent
     to general service of process in any such jurisdiction);

                                       -6-

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                (5)  notify each seller of Registrable Securities, at any time
         when a prospectus relating to those securities is required to be
         delivered under the Securities Act, of the happening of any event as a
         result of which the prospectus included in the registration statement
         contains an untrue statement of a material fact or omits any fact
         necessary to make the statements in the prospectus not misleading; and,
         at the request of any seller, the Company shall prepare a supplement or
         amendment to the prospectus so that, when delivered to purchasers of
         the Registrable Securities, the prospectus, as supplemented or amended,
         does not contain an untrue statement of a material fact or omit to
         state any fact necessary to make the statements in the prospectus not
         misleading;

                (6)  cause all Registrable Securities to be quoted on the Nasdaq
         National Market System;

                (7)  provide a transfer agent and registrar for all such
         Registrable Securities not later than the effective date of the
         registration statement;

                (8)  in the case of an Underwritten Registration, enter into
         such customary agreements (including underwriting agreements in
         customary form) and take all other actions that holders of a majority
         of the Registrable Securities being sold or the underwriters, if any,
         reasonably request in order to expedite or facilitate the disposition
         of the Registrable Securities;

                (9)  make available for inspection by any seller of Registrable
         Securities, any underwriter participating in any disposition pursuant
         to the registration statement and any attorney, accountant or other
         agent retained by any seller or underwriter, all financial and other
         records, pertinent corporate documents and properties of the Company,
         and cause the Company's officers, employees and independent accountants
         to supply all information reasonably requested by any such seller,
         underwriter, attorney, accountant or agent in connection with the
         registration statement;

                (10) otherwise use its best efforts to comply with all
         applicable rules and regulations of the Securities and Exchange
         Commission, and make available to its security holders, as soon as
         reasonably practicable, an earnings statement covering the period of at
         least twelve months beginning with the first day of the Company's first
         full calendar quarter after the effective date of the registration
         statement, which earnings statement shall satisfy the provisions of
         Section 11(a) of the Securities Act and Rule 158; and

                (11) in the event of the issuance of any stop order suspending
         the effectiveness of a registration statement, or of any order
         suspending or preventing the use of any related prospectus or
         suspending the qualification of any Common Stock included in the
         registration statement for sale in any jurisdiction, use its best
         efforts promptly to obtain the withdrawal of such order.

                                       -7-

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         5.  Registration Expenses.

         5A. Payment by Company.

         All Registration Expenses shall be borne as provided in this Agreement,
except that the Company shall, in any event, pay its internal expenses
(including all salaries and expenses of its officers and employees performing
legal or accounting duties), the expense of any annual audit or quarterly review
and the expenses and fees for listing the securities to be registered on the
Nasdaq National Market System.

         5B. Fees of Counsel.

         In connection with each Demand Registration and each Piggyback
Registration, the Company shall reimburse the holders of Registrable Securities
included in the registration for the reasonable fees and disbursements of one
counsel chosen by the holders of a majority of the Registrable Securities
included in the registration and, in the case of an Underwritten Registration or
an underwritten Piggyback Registration, for the reasonable fees of one special
counsel retained by the holders of Registrable Securities to render any required
legal opinions in connection with an underwritten registration which the first
counsel is unable or unwilling to render.

         5C. Payment by Holders.

         To the extent that Registration Expenses are not required to be paid by
the Company, each holder of securities included in any registration under this
Agreement shall pay those Registration Expenses allocable to the registration of
the holder's securities so included, and any Registration Expenses not so
allocable shall be borne by all sellers of securities included in the
registration in proportion to the aggregate selling price of the securities to
be so registered.

         6.  Indemnification.

         6A. Indemnification by Company.

         The Company agrees to indemnify, to the extent permitted by law, each
holder of Registrable Securities, its officers and directors and each Person who
controls such holder (within the meaning of the Securities Act) against all
losses, claims, damages, liabilities and expenses caused by any Violation,
except insofar as the Violation is caused by or contained in any information
furnished in writing to the Company by the holder expressly for use in a
registration statement, prospectus, amendment, supplement or related document or
is caused by the holder's failure to deliver a copy of the registration
statement or prospectus or any amendment or supplements after the Company has
furnished the holder with a sufficient number of copies. In connection with an
underwritten offering, the Company shall indemnify such underwriters, their
officers and directors and each Person who controls such underwriters (within
the meaning of the Securities Act) to the same extent provided in this Section
6(a) with respect to the indemnification of holders of Registrable Securities.

                                       -8-

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         6B. Indemnification by Holder.

         In connection with any registration statement in which a holder of
Registrable Securities is participating, the holder shall furnish to the Company
in writing such information and affidavits as the Company reasonably requests
for use in connection with the registration statement or prospectus and, to the
extent permitted by law, shall indemnify the Company, its directors and officers
and each Person who controls the Company (within the meaning of the Securities
Act) against any losses, claims, damages, liabilities and expenses resulting
from any Violation to the extent that the Violation is caused by or contained in
any information furnished in writing to the Company by the holder expressly for
use in a registration statement, prospectus, amendment, supplement or related
document. This obligation to indemnify shall be individual, not joint and
several, for each holder and shall be limited to the net amount of proceeds
received by the holder from the sale of Registrable Securities pursuant to the
registration statement.

         6C. Procedures.

         Any Person entitled to indemnification under this Section 6 shall give
prompt written notice to the indemnifying party of any claim with respect to
which the Person seeks indemnification (provided that the failure to give prompt
notice shall not impair any Person's right to indemnification to the extent that
the failure has not prejudiced the indemnifying party). Unless in the
indemnified party's reasonable judgment a conflict of interest between the
indemnified and indemnifying parties may exist with respect to the claim for
indemnification, the indemnified party shall permit the indemnifying party to
assume the defense of the claim with counsel reasonably satisfactory to the
indemnified party. If the defense of the claim is assumed by the indemnifying
party, the indemnifying party shall not be subject to any liability for any
settlement made by the indemnified party without its consent (but the
indemnifying party shall not unreasonably withhold its consent). An indemnifying
party who is not entitled to, or who elects not to, assume the defense of a
claim for indemnification shall not be obligated to pay the fees and expenses of
more than one counsel for all parties indemnified by the indemnifying party with
respect to the claim, unless in the reasonable judgment of any indemnified party
a conflict of interest may exist between the indemnified party and any of the
other indemnified parties with respect to the claim.

         6D. Survival.

         The indemnification under this Section 6 shall remain in full force and
effect regardless of any investigation made by or on behalf of the indemnified
party or any officer, director or controlling Person of the indemnified party
and shall survive the transfer of securities. The Company also agrees to make
such provisions as are reasonably requested by any indemnified party for
contribution to the indemnified party in the event that the Company's
indemnification is unavailable for any reason.

         7.  Participation in Underwritten Registration.

         No Person may participate in any underwritten registration pursuant to
this Agreement

                                       -9-

<PAGE>

unless the Person (i) agrees to sell securities on the basis provided in the
underwriting arrangements and (ii) completes and executes all questionnaires,
powers of attorney, indemnities, underwriting agreements and other documents
required under the terms of the underwriting arrangements. In any event,
however, no holder of Registrable Securities included in any underwritten
registration shall be required to make any representations or warranties to the
Company or the underwriters (other than representations and warranties regarding
the holder and the holder's intended method of distribution) or to undertake any
indemnification obligations to the Company or the underwriters except as
otherwise provided in Section 6.

         8.  Miscellaneous.

         8A. No Inconsistent Agreements.

         The Company shall not enter into any agreement with respect to its
securities which is inconsistent with or violates the rights granted to the
holders of Registrable Securities in this Agreement. Without limiting the
generality of the foregoing, until the initial holders of Registrable Securities
cease to hold at least 25% of the number of Registrable Securities initially
acquired by such holders, the Company shall not grant to any Person the right to
request the Company to register any equity securities of the Company, or any
securities convertible or exchangeable into or exercisable for such securities,
without the prior written consent of the holders of a majority of the
Registrable Securities. The Company may grant rights to other Persons to
participate in Piggyback Registrations, however, so long as such rights are
subordinate to the rights of the holders of Registrable Securities with respect
to such Piggyback Registrations as set forth in Sections 2C and 2D of this
Agreement. The Company represents and warrants that, except for the Registration
Agreement dated October 19, 1994 between the Company and certain of its
stockholders, as amended, the Company is not a party to or otherwise subject to
any other agreement granting registration rights to any other Person with
respect to securities of the Company.

         8B. Notices.

         All Notices under this Agreement shall be in writing and sent by
certified or registered mail, overnight messenger service, telecopier or
personal delivery, as follows:

             (a)   if to Stericycle, to:
                                         Stericycle, Inc.
                                         28161 North Keith Drive
                                         Lake Forest, Illinois 60045
                                         Attention:     Mr. Mark C. Miller
                                                        President and Chief
                                                        Executive Officer
                                         Telecopier:    (847) 367-9493

             with a required copy to:

                                      -10-

<PAGE>

                                      Johnson and Colmar
                                      300 South Wacker Drive
                                      Suite 1000
                                      Chicago, Illinois 60606
                                      Attention:   Craig P. Colmar, Esq.
                                      Telecopier:  (312) 922-9283

               (b)  if to an Investor who is a member of the Bain Group, in care
                    of:
                                      Bain Capital Investors, LLC
                                      111 Huntington Avenue
                                      Boston, Massachusetts 02199
                                      Attention:   Mr. Stephen G. Pagliuca
                                                   Mr. Robert Gay
                                                   Mr. John P. Connaughton
                                                   Mr. Joe Pretlow
                                      Telecopier:  (617) 516-2010

               (c)  if to an Investor who is a member of the MDP Group, in care
                    of:
                                      Madison Dearborn Partners, LLC
                                      Three First National Plaza
                                      Suite 3800
                                      Chicago, Illinois 60602
                                      Attention:   Mr. Thomas R. Reusche
                                      Telecopier:  (312) 895-1156

               with a required copy, in the case of a Notice to any Investor,
               to:
                                      Kirkland & Ellis
                                      200 East Randolph Drive
                                      Chicago, Illinois 60601
                                      Attention:   Jeffrey C. Hammes, P.C.
                                      Telecopier:  (312) 861-2200

         All Notices sent by certified or registered mail shall be considered to
have been given three business days after being deposited in the mail. All
Notices sent by overnight courier service, telecopier or personal delivery shall
be considered to have been given when actually received by the intended
recipient. A Party may change its address for purposes of this Agreement by
Notice in accordance with this Section 8B.

         8C.   Waiver.

         The rights and remedies of the Company and holders of Registrable
Securities are cumulative and not alternative. Neither the failure nor any delay
by the Company or any holder

                                       -11-

<PAGE>

of Registrable Securities in exercising any right, power or privilege under this
Agreement shall operate as a waiver of that right, power or privilege, and no
single or partial exercise of any right, power or privilege shall preclude any
other or further exercise of that right, power or privilege or the exercise of
any other right, power or privilege. All waivers shall be in writing signed by
the party to be charged with the waiver, and no waiver that may be given by a
party shall be applicable except in the specific instance for which it is given.

         8D.   Amendment.

         This Agreement may not be amended except by a written agreement signed
by the Company and holders of a majority of the Registrable Securities.

         8E.   Severability.

         If any provision of this Agreement is held invalid or unenforceable by
a court of competent jurisdiction, the other provisions of this Agreement shall
remain in full force and effect. Any provision of this Agreement which is held
invalid or unenforceable only in part shall remain in full force and effect to
the extent not held invalid or unenforceable.

         8F.   Captions.

         The captions of sections of this Agreement are for convenience only and
shall not affect this the construction or interpretation of this Agreement.

         8G.   Construction.

         All references in this Agreement to "Section" or "Sections" refer to
the corresponding section or sections of this Agreement. All words used in this
Agreement shall be construed to be of the appropriate gender or number as the
context requires. Unless otherwise expressly provided, the word "including" does
not limit the preceding words or terms.

         8H.   Counterparts.

         This Agreement may be executed in one or more counterparts, each of
which shall be considered an original copy of this Agreement and all of which,
when taken together, shall be considered to constitute one and the same
agreement.

         8I.   Governing Law.

         This Agreement shall be governed by the Laws of the State of Illinois
without regard to conflicts of laws principles.

         8J.  Binding Effect.

         This Agreement shall apply to, be binding in all respects upon and
inure to the benefit of

                                      -12-

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Parties and their respective successors and permitted assigns.

                                       -13-

<PAGE>

         In witness, the Parties have executed this Agreement.

Company:

                                  Stericycle, Inc.

                                  By:  /s/ Mark C. Miller
                                     -------------------------------------------
                                           President and Chief Executive Officer

                               MDP Entities:

                                  Madison Dearborn Capital Partners III, L.P.

                                  By:  Madison Dearborn Partners III, L.P.
                                  Its: General partner

                                  By:  Madison Dearborn Partners, LLC
                                  Its: General Partner

                                  By:  /s/ Thomas R. Reusche
                                     -------------------------------------------
                                           A Managing Director

                                  Madison Dearborn Special Equity III, L.P.

                                  By:  Madison Dearborn Partners III, L.P.
                                  Its: General partner

                                  By:  Madison Dearborn Partners, LLC
                                  Its: General Partner

                                  By:  /s/ Thomas R. Reusche
                                       -----------------------------------------
                                           A Managing Director

                                  Madison Dearborn Capital Partners III, L.P.

                                  By:  Madison Dearborn Partners III, L.P.
                                  Its: General partner

                                  By:  Madison Dearborn Partners, LLC
                                  Its: General Partner

                                  By:  /s/ Thomas R. Reusche
                                       -----------------------------------------
                                           A Managing Director

                                      -14-

<PAGE>

                               Bain Entities:

                                  Bain Capital Fund VI, L.P.

                                  By:  Bain Capital Partners VI, L.P.
                                  Its: General Partner

                                  By:  Bain Capital Investors, LLC
                                  Its: General Partner

                                  By:  /s/ Paul Edgerly
                                       -----------------------------------------
                                           A Managing Director

                                  BCIP Associates II

                                  By:  Bain Capital Investors, LLC
                                  Its: Managing General Partner

                                  By:  /s/ Paul Edgerly
                                       -----------------------------------------
                                         Name:
                                         Title:

                                  BCIP Associates II-B

                                  By:  Bain Capital Investors, LLC
                                  Its: Managing General Partner

                                  By:  /s/ Paul Edgerly
                                       -----------------------------------------
                                         Name:
                                         Title:

                                  BCIP Associates II-C

                                  By:  Bain Capital Investors, LLC
                                  Its: Managing General Partner

                                  By:  /s/ Paul Edgerly
                                       -----------------------------------------
                                         Name:
                                         Title:

                                      -15-

<PAGE>

                            BCIP Trust Associates II

                            By:  Bain Capital Investors, LLC
                            Its: Managing General Partner

                            By:  /s/ Paul Edgerly
                                ------------------------------------------------
                                   Name:
                                   Title:

                            BCIP Trust Associates II-B

                            By:  Bain Capital Investors, LLC
                            Its: Managing General Partner

                            By:  /s/ Paul Edgerly
                                ------------------------------------------------
                                   Name:
                                   Title:

                            Pep Investments Pty. Limited

                            By:  Bain Capital Investors, LLC
                            Its: Attorney-in-Fact

                            By:
                                ------------------------------------------------
                                   Name:
                                   Title:

                            Brookside Capital Partners Fund, L.P.

                            By:  /s/ Ed Brakeman
                                ------------------------------------------------
                                   Name: Ed Brakeman
                                   Title: Managing Director

                            Sankaty High Yield Asset Partners, L.P.

                            By:  /s/ Kristin Mugford
                                ------------------------------------------------
                                   Name: Kristin Mugford
                                   Title: Managing Director

                            Sankaty High Yield Partners II, L.P.

                            By:  /s/ Kristin Mugford
                                ------------------------------------------------
                                   Name: Kristin Mugford
                                   Title: Managing Director

                                      -16-

<PAGE>

                                   Schedule A

                                  Defined Terms

     Current Preferred Shares means the shares of Preferred Stock listed under
the caption "Preferred Shares" on the attached Schedule I.

     Exchange Act means the Securities Exchange Act of 1934, as amended.

     Group means either:

         (a)   the group (the "Bain Group") consisting of

               (1) the Investors listed under the caption "Bain Entities" on the
         attached Schedule I (for as long as each such Investor continues to be
         the beneficial owner of Registrable Securities), and

               (2) the Permitted Transferees of such Investors (for as long as
         each such Permitted Transferee continues to be the beneficial owner of
         Registrable Securities); or

         (b)   the group (the "MDP Group") consisting of

               (1) the Investors listed under the caption "MDP Entities" on the
         attached Schedule I (for as long as each such Investor continues to be
         the beneficial owner of Registrable Securities), and

               (2) the Permitted Transferees of such Investors (for as long as
         each such Permitted Transferee continues to be the beneficial owner of
         Registrable Securities).

     Person means an individual, partnership, corporation, limited liability
company, association, trust, unincorporated organization, or other entity.

     Permitted Transferee is defined in the Corporate Governance Agreement (as
amended and restated pursuant to the Waiver Agreement).

     Registrable Securities means (i) any shares of Common Stock issued or
issuable upon conversion of the Current Preferred Shares and (ii) any shares of
Common Stock issued or issuable (A) as a dividend or distribution in respect of,
or (B) in exchange for or replacement of, or (C) upon conversion or exercise of
any warrant or other security issued or issuable as a dividend or distribution
in respect of or in exchange for or replacement of, the Current Preferred Shares
and any shares of Common Stock issued or issuable upon conversion of the Current

                                      -17-

<PAGE>

Preferred Shares. Any Registrable Securities shall cease to be Registrable
Securities if and when they (or, in respect of issuable but not yet issued
Registrable Securities, the underlying Preferred Stock or Common Stock) cease to
be beneficially owned by a member of a Group.

     Registration Expenses means all expenses incident to the Company's
performance of or compliance with this Agreement, including all registration and
filing fees, fees and expenses of compliance with securities or blue sky laws,
printing expenses, messenger and delivery expenses, fees and disbursements of
custodians, and fees and disbursements of counsel for the Company and all
independent certified public accountants, underwriters (excluding discounts,
commissions and underwriters' counsel fees) and other Persons retained by the
Company.

     Securities Act means the Securities Act of 1933, as amended.

     Violation means any of the following statements, omissions or violations:
(i) any untrue statement or alleged untrue statement of a material fact
contained in a registration statement under this Agreement, including any
related preliminary or final prospectus, any amendment or supplement, or any
document filed under state securities or "blue sky" laws, (ii) the omission or
alleged omission to state a material fact required to be stated in any such
registration statement, prospectus, amendment, supplement or document or
necessary to make the statements in any such registration statement, prospectus,
amendment, supplement or document not misleading, or (iii) any violation or
alleged violation by the Company of the Securities Act, the Exchange Act, any
state securities law, or any rule or regulation promulgated under the Securities
Act, the Exchange Act or any state securities law.

                                      -18-

<PAGE>

                                   Schedule I

                                Preferred Shares

<TABLE>
<CAPTION>
                                                                     Preferred
                                                                      Shares
<S>                                                                   <C>
MDP Entities

   Madison Dearborn Capital Partners III, L.P.....................    22,267.55
   Madison Dearborn Special Equity III, L.P.......................       494.44
   Special Advisors Fund I, LLC...................................        91.42
                                                                      ---------
     Total........................................................    22,853.41

Bain Entities

   Bain Capital Fund VI, L.P......................................    15,437.45
   BCIP Associates II.............................................     2,732.19
   BCIP Associates II-B...........................................       374.57
   BCIP Associates II-C...........................................       802.00
   BCIP Trust Associates..........................................       781.81
   BCIP Trust Associates II-B.....................................       124.77
   PEP Investments Pty. Limited...................................        51.45
   Brookside Capital Partners Fund L.P............................     1,123.92
   Sankaty High Yield Asset Partners, L.P.........................       561.96
   Sankaty High Yield Partners II, L.P............................       561.96
                                                                      ---------
     Total........................................................    22,552.07

Grand Total.......................................................    45,405.47
                                                                      =========
</TABLE>

                                      -19-<PAGE>

                                                                    Exhibit 10.1

                                 Amendment No. 1
                                       To
                      Amended and Restated Credit Agreement

     This Amendment No. 1 To Amended and Restated Credit Agreement (the
"Agreement") is being executed and delivered as of June 28, 2002 by and among
Stericycle, Inc., a Delaware corporation (the "Borrower"), each of the
Subsidiary Guarantors named as signatories hereto, the financial institutions
from time to time party to the Credit Agreement referred to and defined below
(collectively, the "Lenders") and Bank of America, N.A., as representative of
the Lenders (in such capacity, the "Administrative Agent"). Undefined
capitalized terms used herein shall have the meanings ascribed to such terms in
such Credit Agreement as defined below.

                              W I T N E S S E T H:

     WHEREAS, the Borrower, the Lenders, the Administrative Agent, Credit Suisse
First Boston, as the Co-Syndication Agent, UBS Warburg, LLC, as the
Co-Syndication Agent, and Fleet National Bank, as the Documentation Agent, have
entered into that certain Amended and Restated Credit Agreement dated as of
October 5, 2001 (the "Credit Agreement"), pursuant to which, among other things,
the Lenders have agreed to provide, subject to the terms and conditions
contained therein, certain loans to the Borrower;

     WHEREAS, in connection with the Credit Agreement, (i) the Borrower has
executed and delivered a certain Security and Pledge Agreement and other Loan
Documents pursuant to which it has granted liens and security interests in
substantially all of its properties as security for its obligations with respect
to the Credit Agreement and (ii) the Subsidiary Guarantors have each executed
and delivered in favor of the Administrative Agent and the Lenders, a certain
Subsidiary Guaranty, Security and Pledge Agreement and certain other Loan
Documents pursuant to which the Subsidiary Guarantors have guaranteed the
Borrower's obligations under the Credit Agreement and the Subsidiary Guarantors
have granted liens and security interests in substantially all of their
properties as security for obligations with respect to the Credit Agreement;

     WHEREAS, to facilitate Borrower's desire to effect certain redemptions or
repurchases with respect to its outstanding Capital Stock, the Borrower has
requested that the Lenders, and subject to the terms and conditions set forth
herein, the Lenders have agreed to amend the Credit Agreement to, among other
things, (i) increase the aggregate Revolving Loan Commitment Amount from
$80,000,000 to $105,000,000 and (ii) modify the covenants which restrict the
amount of Restricted Payments the Borrower may make in connection with the
repurchase or redemption of its Capital Stock and the redemption of its
Subordinated Notes; and

     WHEREAS, in anticipation of effecting the increase in the Revolving Loan
Commitment Amount and the addition of a new Lender, (i) the Revolving Loan
Lenders have agreed to sell

<PAGE>

and assign certain portions of their outstanding Revolving Loans under the
Credit Agreement to certain of the Lenders, and (ii) the Revolving Loan Lenders
hereunder have agreed to reallocate their respective Commitments and interests
in the existing Revolving Loans under the Credit Agreement;

     NOW, THEREFORE, in consideration of the foregoing premises, the terms and
conditions stated herein and other valuable consideration, the receipt and
sufficiency of which are hereby acknowledged by the Borrower, the Subsidiary
Guarantors, the Lenders and the Administrative Agent, such parties hereby agree
as follows:

     1.   Amendment.

     Subject to the satisfaction of each of the conditions set forth in
Paragraph 2 of this Agreement, the Credit Agreement is hereby amended as follows
(unless otherwise specified, section and schedule references used herein shall
mean and refer to sections and schedules of the Credit Agreement):

          (a)  Section 1.1 is amended to:

               (i)  insert in appropriate alphabetical order the following
          definitions:

                    " `Amendment No. 1' means that certain Amendment No. 1 to
               Amended and Restated Credit Agreement dated June 28, 2002 among
               the Borrower, the Subsidiary Guarantors signatories thereto, the
               Lenders and the Administrative Agent."

                    " `Amendment No. 1 Effective Date' means the date on which
               the Administrative Agent has received each of items set forth in
               Paragraph 2 of Amendment No. 1."

                    " `Amendment No. 1 Purchasing Lender' means each financial
               institution designated as a `Purchasing Lender' on Schedule IV
               attached hereto."

                    " `Resulting Lender' means each Lender having a Revolving
               Loan Commitment immediately after the Amendment No. 1 Effective
               Date."

                    " `Amendment No. 1 Selling Lender' means each financial
               institution designated as a `Selling Lender' on Schedule IV
               attached hereto."

               (ii) delete in its entirety the definition of "Revolving Loan
          Commitment" and to replace such definition with the following
          definition:

                    " `Revolving Loan Commitment' means, relative to any Lender,
               such Lender's obligation, if any, to (i) purchase outstanding
               `Loans' under and as

                                       -2-

<PAGE>

               defined in the Original Credit Agreement and designated to be
               converted into or continued as Revolving Loans hereunder pursuant
               to the Master Assignment Agreement, its agreement hereunder to
               amend and restate the terms governing such `Loans', (ii) to
               purchase `Loans' pursuant to the terms of Section 10.11.3 and
               (iii) its obligation to make Revolving Loans pursuant to clause
               (a) of Section 2.1.1."

               (iii) delete from the definition of "Revolving Loan Commitment
          Amount" the dollar amount "$80,000,000" in the first line thereof and
          to replace such dollar amount with "$105,000,000".

               (iv)  delete from the definition of "RL Percentage" the clause
          "below its signature on the signature pages hereto" in the second line
          thereof and to replace such clause with the clause "on Schedule III
          hereto".

          (b)  Section 7.2.4 is amended to delete subsection (c) in its entirety
     and to replace such subsection (c) with the following:

               "(c)  The Borrower will not permit Net Worth, at any time after
          the Effective Date, to be less than the sum of (i) $245,000,000 plus,
          (ii) 50% of the sum of Net Income for each Fiscal Quarter ending
          during the period April 1, 2002 through the last day of the then most
          recently ended Fiscal Quarter after the Effective Date with respect to
          which the Borrower shall have delivered, or is obligated to then
          deliver, quarterly financial statements and a Compliance Certificate
          pursuant to Section 7.1.1, excluding from such sum, however, any such
          Fiscal Quarter's Net Income which is negative, plus, (iii) 50% of the
          aggregate amount of Net Equity Proceeds received by the Borrower after
          the Effective Date, minus (iv) the aggregate consideration paid by the
          Borrower after the Amendment No. 1 Effective Date for the repurchase,
          redemption or retirement of its Capital Stock pursuant to Section
          7.2.6(a) or Section 7.2.6(c), but only to the extent such aggregate
          amount is less than or equal to $50,000,000."

          (c)  Section 7.2.6 is amended to delete subsection (b) in its entirety
     and to replace such subsection (b) with the following:

               "(b)  redeem, defease or otherwise prepay or retire the
          Subordinated Notes, including, without limitation, pursuant to a
          Qualified Subordinated Note Redemption, provided, that, except in the
          case of a Qualified Subordinated Note Redemption completed prior to
          the Amendment No. 1 Effective Date:

                     (1)  immediately after giving effect to such redemption,
               defeasance, prepayment or retirement, the Leverage Ratio shall be
               less than or equal to 2.50:1.00 and the Senior Leverage Ratio
               shall be less than or equal to 2.00:1.00, in each case calculated
               based upon the Leverage Ratio and Senior Leverage Ratio set forth
               in the Compliance Certificate then most recently

                                       -3-

<PAGE>

               delivered by the Borrower to the Administrative Agent pursuant to
               Section 7.1.1(c); or

                    (2) (A) such redemption, defeasance, prepayment or
               retirement is made after the Amendment No. 1 Effective Date, but
               prior to December 31, 2002, and (B) immediately after giving
               effect to such redemption, defeasance, prepayment or retirement,
               the Leverage Ratio shall be less than or equal to 3.25:1.00 and
               the Senior Leverage Ratio shall be less than or equal to
               2.75:1.00, in each case calculated based upon the Leverage Ratio
               and Senior Leverage Ratio set forth in the Compliance Certificate
               then most recently delivered by the Borrower to the
               Administrative Agent pursuant to Section 7.1.1(c) and (C) the
               total aggregate amount of such Restricted Payments made after the
               Amendment No. 1 Effective Date pursuant to this clause (b), shall
               not exceed 10% of Net Worth at the time of such redemption,
               defeasance, prepayment or retirement, immediately after giving
               effect to such redemption, defeasance, prepayment or retirement;
               or

                    (3) (A) such redemption, defeasance, prepayment or
               retirement is made on or after January 1, 2003 and (B)
               immediately after giving effect to such redemption, defeasance,
               prepayment or retirement, the Leverage Ratio shall be less than
               or equal to 3.00:1.00 and the Senior Leverage Ratio shall be less
               than or equal to 2.50:1.00, in each case calculated based upon
               the Leverage Ratio and Senior Leverage Ratio set forth in the
               Compliance Certificate then most recently delivered by the
               Borrower to the Administrative Agent pursuant to Section 7.1.1(c)
               and (C) the total aggregate amount of Restricted Payments made
               after the Amendment No. 1 Effective Date pursuant to this clause
               (b) and pursuant to clause (c) of this section, does not exceed
               the difference of (i) 10% of Net Worth at the time of such
               redemption, defeasance, prepayment or retirement, immediately
               after giving effect to such redemption, defeasance, prepayment or
               retirement, minus (ii) the aggregate consideration paid by the
               Borrower after the Amendment No. 1 Effective Date for the
               repurchase, retirement or redemption of its Capital Stock
               pursuant to Section 7.2.6(a) and Section 7.2.6(c), but only to
               the extent such aggregate consideration exceeds $65,000,000;"

          (d)  Section 7.2.6 is further amended to delete subsection (c) in its
     entirety and to replace such subsection (c) with the following:

               "(c) declare, pay and make Restricted Payments consisting of
          dividends, repurchases or redemptions with respect to the Borrower's
          Capital Stock, in addition to those permitted by the foregoing clause
          (a) of this section, provided, that,

                    (1) immediately after giving effect to any such Restricted
               Payments, the Leverage Ratio shall be less than or equal to
               2.50:1.00, calculated based

                                       -4-

<PAGE>

               upon the Leverage Ratio set forth in the Compliance Certificate
               then most recently delivered by the Borrower to the
               Administrative Agent pursuant to Section 7.1.1(c); or

                    (2) (A) immediately after giving effect to such Restricted
               Payments, the Leverage Ratio shall be less than or equal to
               3.25:1.00, calculated based upon the Leverage Ratio set forth in
               the Compliance Certificate then most recently delivered by the
               Borrower to the Administrative Agent pursuant to Section 7.1.1(c)
               and (B) the total aggregate amount of such Restricted Payments
               made after the Amendment No. 1 Effective Date pursuant to this
               clause (c)(2) after giving effect to such Restricted Payments
               shall not exceed $65,000,000, provided, further, however, that
               notwithstanding anything to the contrary in this clause (c), any
               Restricted Payments which are permitted by this clause (c)(2) and
               which are also permitted by either clause (c)(1) or clause (c)(3)
               shall be deemed to have been made pursuant to this clause (c)(2)
               (and not pursuant to clause (c)(1) or clause (c)(3), as the case
               may be) until such time as such Restricted Payments made pursuant
               to this clause (c)(2) equal $65,000,000; or

                    (3) (A) such Restricted Payments are made on or after
               January 1, 2003 and (B) immediately after giving effect to such
               Restricted Payments, the Leverage Ratio shall be less than or
               equal to 3.00:1.00, calculated based upon the Leverage Ratio set
               forth in the Compliance Certificate then most recently delivered
               by the Borrower to the Administrative Agent pursuant to Section
               7.1.1(c) and (C) the total aggregate amount of such Restricted
               Payments made after the Amendment No. 1 Effective Date pursuant
               to this clause (c)(3) and clause (c)(1) of this section and
               pursuant to clause (b) of this section (but not including
               Restricted Payments made after the Amendment No. 1 Effective Date
               pursuant to clause (c)(2) of this section) shall not exceed 10%
               of Net Worth at the time of the making of such Restricted
               Payments immediately after giving effect to such Restricted
               Payments;"

          (e)  Section 10.11 is amended to insert the following Section 10.11.3
     thereto immediately following Section 10.11.2:

          "SECTION 10.11.3   2002 Assignments.

               (a)  As of the Amendment No. 1 Effective Date, each of the
          Amendment No. 1 Selling Lenders hereby sells and assigns to the each
          of the Amendment No. 1 Purchasing Lenders, and each of the Amendment
          No. 1 Purchasing Lenders hereby purchases and assumes from each of the
          Amendment No. 1 Selling Lenders, certain of each Amendment No. 1
          Selling Lender's interests in the Revolving Loans and participation
          interests in the Letter of Credit Outstandings (collectively, the
          `Interests'), and each of the Resulting Lenders hereby agrees to
          reallocate among such Resulting Lenders their respective Commitments
          and interests in the

                                       -5-

<PAGE>

          outstanding Revolving Loans and Letter of Credit Outstandings, in each
          case such that after giving effect to such sales, assignments,
          purchases, assumptions and reallocations, each Resulting Lender shall
          have the resulting Interests as are set forth on Schedule IV beside
          its name therein under the heading `6/28/02 Revolver Reallocated
          Outstandings'. The sales, assignments, purchases, assumptions and
          reallocations to be effected pursuant to this paragraph shall be
          without recourse to, or representation or warranty (except as
          expressly provided in this Section 10.11.3) by, any of the Resulting
          Lenders.

               (b)  Each of the Amendment No. 1 Selling Lenders (i) represents
          and warrants that it is the legal and beneficial owner of the
          Interests and Commitments, if any, being sold and assigned by it
          hereunder and that such Interests are free and clear of any adverse
          claim; (ii) makes no representation or warranty and assumes no
          responsibility with respect to any statements, warranties or
          representations made by the Borrower in or in connection with the
          Credit Agreement or Amendment No. 1; and (iii) makes no representation
          or warranty and assumes no responsibility with respect to the
          financial condition of the Borrower or its Affiliates or the
          performance or observance by the Borrower or its Affiliates of any of
          their respective obligations under the Credit Agreement or any other
          instrument or document furnished pursuant thereto.

               (c)  Each of the Amendment No. 1 Selling Lenders will deliver to
          the Administrative Agent each existing Note evidencing any portion of
          such Amendment No. 1 Selling Lender's interests in the outstanding
          Revolving Loans and Letter of Credit Outstandings owed by the Borrower
          to such Amendment No. 1 Selling Lender prior to giving effect to the
          sales and assignments being effected hereby (the `Old Notes'). Upon
          receipt by the Administrative Agent from each Amendment No. 1 Selling
          Lender of its Old Notes, and receipt from the Borrower of the
          substituted and amended notes payable to the Resulting Lenders and to
          be delivered by the Borrower pursuant to Amendment No. 1 (the `New
          Notes'), the Administrative Agent will return the Old Notes to the
          Borrower marked `substituted and amended' and deliver the New Notes to
          each applicable Resulting Lender.

               (d)  The effective date of the sales, assignments, purchases,
          assumptions and reallocations to be effected by this Section 10.11.3
          shall be the date on which all of the conditions to effectiveness of
          the Amendment No. 1 shall have been satisfied.

               (e)  As of the Amendment No. 1 Effective Date, (i) the Amendment
          No. 1 Purchasing Lenders shall be a party to the Credit Agreement, as
          amended pursuant to Amended No. 1, and, to the extent provided in this
          Section 10.11.3, shall have the rights and obligations of a `Lender'
          thereunder, and (ii) each of the Amendment No. 1 Selling Lenders
          shall, to the extent provided in this Section 10.11.3, relinquish its
          respective rights and be released from its obligations under the
          Credit Agreement, as amended by Amendment No. 1.

                                       -6-

<PAGE>

               (f)  From and after the Amendment No. 1 Effective Date, the
          Administrative Agent shall make all payments under the Credit
          Agreement in respect of the Interests assigned hereby (including all
          payments of principal, interest and fees with respect thereto) to the
          Resulting Lenders.

               (g)  All interest and fees under the Credit Agreement which are
          accrued and unpaid through the Amendment No. 1 Effective Date with
          respect to the Interests assigned and Commitments reallocated hereby
          shall be for the account of the Amendment No. 1 Selling Lenders and,
          upon the Administrative Agent's receipt from the Borrower of payment
          of such interest and fees, the Administrative Agent shall allocate
          such payments among the Amendment No. 1 Selling Lenders and the
          Amendment No. 1 Purchasing Lenders accordingly."

               (f)  The Credit Agreement is amended to attach thereto the
          Schedule III and Schedule IV attached hereto as Exhibit A and Exhibit
          B, respectively.

     2.   Effectiveness of this Agreement; Conditions Precedent.

     The provisions of Paragraph 1 of this Agreement shall be deemed to have
become effective as of the date of this Agreement, but such effectiveness shall
be expressly conditioned upon the Administrative Agent's receipt of each of the
following:

          (a)  an originally-executed counterpart of this Agreement executed and
     delivered by duly authorized officers of the Borrower, the Subsidiary
     Guarantors and the Required Lenders;

          (b)  restated and amended Revolving Notes made payable to each
     Revolving Loan Lender with respect to each of their Revolving Loan
     Commitments, as proposed to be amended hereby and in form and substance
     acceptable to the Administrative Agent;

          (c)  certificates of the secretary or assistant secretary of the
     Borrower certifying (i) the currency and authenticity of the resolutions of
     the board of directors of the Borrower authorizing its execution and
     delivery of this Agreement and the performance hereof and of the Credit
     Agreement as to be amended hereby, (ii) the incumbency of the officers of
     the Borrower and (iii) the currency and authenticity of the Organic
     Documents of the Borrower;

          (d)  a good standing certificate for the Borrower from the State of
     Delaware, as of a date no earlier than 30 days prior to the date each of
     the other conditions of this paragraph shall have been satisfied;

          (e)  a certificate signed by an officer, dated as of the date each of
     the other conditions set forth in this paragraph shall have been satisfied,
     stating that, after giving effect to the amendments contemplated by this
     Agreement: (i) the representations and warranties contained in Article VI
     of the Credit Agreement (other than representations

                                       -7-

<PAGE>

          and warranties which, in accordance with their express terms, are made
          only as of an earlier specified date) are true and correct in all
          material respects as of date and (ii) no Default or Event of Default
          exists or would result therefrom;

               (f)  payment in full, in immediately available funds by the
          Borrower of the amounts described in Section 10.11.3(g) of the Credit
          Agreement, as amended by this Agreement;

               (g)  a legal opinion from Johnson & Colmar, special counsel to
          the Obligors, addressed to the Administrative Agent and the Lenders,
          in form and substance acceptable to the Administrative Agent; and

               (h)  payment in full, in immediately available funds, of (i) the
          fee payable to each Lender who is increasing its Revolving Loan
          Commitment as set forth in separate agreements among the each such
          Lender, the Administrative Agent and the Borrower and (ii) the
          arrangement fee payable to the Administrative Agent as set forth in a
          separate agreement between the Administrative Agent and the Borrower.

          3.   Representations, Warranties and Covenants.

               (a)  The Borrower hereby represents and warrants that this
          Agreement and the Credit Agreement as amended by this Agreement
          constitute the legal, valid and binding obligations of the Borrower
          enforceable against the Borrower in accordance with their terms.

               (b)  The Borrower hereby represents and warrants that its
          execution, delivery and performance of this Agreement and the Credit
          Agreement as amended by this Agreement have been duly authorized by
          all proper corporate action, do not violate any provision of its
          certificate of incorporation or bylaws, will not violate any law,
          regulation, court order or writ applicable to it, and will not require
          the approval or consent of any governmental agency, or of any other
          third party under the terms of any contract or agreement to which the
          Borrower or any of the Borrower's Affiliates is bound, including,
          without limitation, the Subordinated Debt Documents.

               (c)  The Borrower hereby represents and warrants that, after
          giving effect to the provisions of this Agreement, (i) no Default or
          Event of Default has occurred and is continuing or will have occurred
          and be continuing and (ii) all of the representations and warranties
          of the Borrower contained in the Credit Agreement and in each other
          Loan Document (other than representations and warranties which, in
          accordance with their express terms, are made only as of an earlier
          specified date) are, and will be, true and correct as of the date of
          the Borrower's execution and delivery hereof or thereof in all
          material respects as though made on and as of such date.

                                       -8-

<PAGE>

     4.   Reaffirmation, Ratification and Acknowledgment; Reservation.

     The Borrower and each Subsidiary Guarantor hereby (a) ratifies and
reaffirms all of its payment and performance obligations, contingent or
otherwise, and each grant of security interests and liens in favor of the
Administrative Agent, under each Loan Document to which it is a party, (b)
agrees and acknowledges that such ratification and reaffirmation is not a
condition to the continued effectiveness of such Loan Documents, and (c) agrees
that neither such ratification and reaffirmation, nor the Administrative
Agent's, or any Lender's solicitation of such ratification and reaffirmation,
constitutes a course of dealing giving rise to any obligation or condition
requiring a similar or any other ratification or reaffirmation from the Borrower
or such Subsidiary Guarantors with respect to any subsequent modifications to
the Credit Agreement or the other Loan Documents. The Credit Agreement is in all
respects ratified and confirmed. Each of the Loan Documents shall remain in full
force and effect and are hereby ratified and confirmed. Neither the execution,
delivery nor effectiveness of this Agreement shall operate as a waiver of any
right, power or remedy of the Administrative Agent or the Lenders, or of any
Default or Event of Default (whether or not known to the Administrative Agent or
the Lenders), under any of the Loan Documents, all of which rights, powers and
remedies, with respect to any such Default or Event of Default or otherwise, are
hereby expressly reserved by the Administrative Agent and the Lenders. This
Agreement shall constitute a Loan Document for purposes of the Credit Agreement.

     5.   Governing Law.

     THIS AGREEMENT SHALL BE DEEMED TO BE A CONTRACT MADE UNDER AND GOVERNED BY
AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK (INCLUDING
SECTIONS 5-1401 AND 5-1402 OF THE GENERAL OBLIGATIONS LAW OF THE STATE OF NEW
YORK).

     6.   Administrative Agent's Expenses.

     The Borrower hereby agrees to promptly reimburse the Administrative Agent
for all of the reasonable out-of-pocket expenses, including, without limitation,
attorneys' and paralegals' fees, it has heretofore or hereafter incurred or
incurs in connection with the preparation, negotiation and execution of this
Agreement, the 2002 Master Lender Assignment Agreement and the other related
Loan Documents.

     7.   Counterparts.

     This Agreement may be executed in counterparts, each of which shall be an
original and all of which together shall constitute one and the same agreement
among the parties.

                                     * * * *

                                       -9-

<PAGE>

     IN WITNESS WHEREOF, this Agreement has been duly executed as of the day and
year first above written.

                                Stericycle, Inc., as Borrower

                                By:     /s/ Frank J.M. ten Brink
                                      ------------------------------------------
                                Title:      Frank ten Brink
                                            Vice President

                                Stericycle of Arkansas, Inc.,
                                     an Arkansas corporation
                                Stericycle of Washington, Inc.,
                                     a Washington corporation
                                SWD Acquisition Corp.,
                                     a Delaware corporation
                                Environmental Control Co., Inc.,
                                     a New York corporation,
                                Waste Systems, Inc.,
                                     a Delaware corporation
                                Med-Tech Environmental, Inc.,
                                     a Delaware corporation
                                Med-Tech Environmental (MA), Inc.,
                                     a Delaware corporation,
                                Ionization Research Co., Inc.,
                                     a California corporation,
                                Browning-Ferris Industries of Connecticut, Inc.,
                                     a Delaware corporation
                                BFI Medical Waste, Inc.,
                                     a Delaware corporation,
                                American Medical Disposal, Inc.,
                                     an Oklahoma corporation,
                                Environmental Health Systems, Inc.,
                                     a Nebraska corporation
                                Stroud Properties, Inc.,
                                     a Delaware corporation,
                                each as a Subsidiary Guarantor

                                By:     /s/ Frank J.M. ten Brink
                                      ------------------------------------------
                                Title:      Frank ten Brink
                                            Vice President

<PAGE>

                                  Allied Irish Banks PLC

                                  By:    /s/ Rima Terradista
                                        ----------------------------------------
                                             Rima Terrdista
                                             Senior Vice President

                                  By:    /s/ John Farrace
                                        ----------------------------------------
                                             John Farrace
                                             Senior Vice President

                                  American National Bank and Trust Company of
                                  Chicago

                                  By:        [signature illegible]
                                        ----------------------------------------
                                  Title:     VP

                                  Bank of America, N.A., as Administrative Agent

                                  By:    /s/ Kristine Thennes
                                        ----------------------------------------
                                  Title:

                                  Bank of America, N.A., as a Lender

                                  By:    /s/ Jennifer Gerdes
                                        ----------------------------------------
                                  Title:     Vice President

                                  Fleet National Bank

                                  By:    /s/ Brian F.X. Gephardt
                                        ----------------------------------------
                                  Title:     Managing Director

                                  Comerica Bank

                                  By:    /s/ Felicia M. Maxwell
                                        ----------------------------------------
                                  Title:     Felicia M. Maxwell
                                             Assistant Vice President

                                  Credit Suisse First Boston

                                  By:    /s/ Kristin Lepri/Jay Chall
                                        ----------------------------------------
                                  Title:     Kristin Lepri, Associate
                                             Jay Chall, Director

<PAGE>

                                  Credit Lyonnais New York Branch

                                  By:        [signature illegible]
                                        ----------------------------------------
                                  Title:

                                  Harris Trust & Savings Bank

                                  By:        [signature illegible]
                                        ----------------------------------------
                                  Title:     Vice President

                                  LaSalle Bank National Association

                                  By:    /s/ Brian Peterson
                                        ----------------------------------------
                                             Brian Peterson
                                             First Vice President

                                  ELT Ltd

                                  By:    /s/ Kelly W. Warnement
                                        ----------------------------------------
                                  Title:     Kelly W. Warnement
                                             Authorized Agent

                                  KZH Riverside LLC

                                  By:    /s/ Anthony Iarrobino
                                        ----------------------------------------
                                  Title:     Anthony Iarrobino
                                             Authorized Agent

                                  KZH Soleil-2 LLC

                                  By:    /s/ Anthony Iarrobino
                                        ----------------------------------------
                                  Title:     Anthony Iarrobino
                                             Authorized Agent

                                  Muirfield Trading LLC

                                  By:    /s/ Kelly W. Warnement
                                        ----------------------------------------
                                  Title:     Kelly W. Warnement
                                             Vice President

<PAGE>

                                  Eaton Vance CDO III, Ltd.
                                  By:   Eaton Vance Management as Investment
                                        Advisor

                                  By:    /s/ Payton F. Swaffield
                                        ----------------------------------------
                                  Title:     Peyton F. Swaffield
                                             Vice President

                                  Eaton Vance CDO IV, Ltd.
                                  By:   Eaton Vance Management as Investment
                                        Advisor

                                  By:    /s/ Payton F. Swaffield
                                        ----------------------------------------
                                  Title:     Peyton F. Swaffield
                                             Vice President

                                  Eaton Vance Senior Income Trust
                                  By:   Eaton Vance Management as Investment
                                        Advisor

                                  By:    /s/ Payton F. Swaffield
                                        ----------------------------------------
                                  Title:     Peyton F. Swaffield
                                             Vice President

                                  Eaton Vance Instiutional Senior Loan Fund
                                  By:   Eaton Vance Management as Investment
                                        Advisor

                                  By:    /s/ Payton F. Swaffield
                                        ----------------------------------------
                                  Title:     Peyton F. Swaffield
                                             Vice President

                                  Costantinus Eaton Vance CDO V, Ltd.
                                  By:   Eaton Vance Management as Investment
                                        Advisor

                                  By:    /s/ Payton F. Swaffield
                                        ----------------------------------------
                                  Title:     Peyton F. Swaffield
                                             Vice President

<PAGE>

                                  Grayson & Co.
                                  By:   Boston Management and Research as
                                        Investment Advisor

                                  By:    /s/ Payton F. Swaffield
                                        ----------------------------------------
                                  Title:     Peyton F. Swaffield
                                             Vice President

                                  Sankaty Advisors, LLC as Collateral Manager
                                  for Great Point CLO 1999-1 LTD., as Term
                                  Lender

                                  By:    /s/ Diane J. Exeter
                                        ----------------------------------------
                                  Name:      Diane J. Exeter
                                  Title:     Managing Director
                                             Portfolio Manager

                                  Harbour Town Funding LLC

                                  By:    /s/ Kelly W. Warnement
                                        ----------------------------------------
                                  Title:     Kelly W. Warnement
                                             Vice President

                                  The Northern Trust Company

                                  By:    /s/ Eileen L. Sachanda
                                        ----------------------------------------
                                  Title:     Vice President

                                  Olympic Funding Trust, Series 1999-I

                                  By:    /s/ Kelly W. Warnement
                                        ----------------------------------------
                                  Title:     Kelly W. Warnement
                                             Authorized Agent

                                  Oxford Strategic Income Fund
                                  By:   Eaton Vance Management as Investment
                                        Advisor

                                  By:    /s/ Payton F. Swaffield
                                        ----------------------------------------
                                  Title:     Peyton F. Swaffield
                                             Vice President

<PAGE>

                                  PPM Spyglass Funding Trust

                                  By:    /s/ Kelly W. Warnement
                                        ----------------------------------------
                                  Title:     Kelly W. Warnement
                                             Authorized Agent

                                  PPM Shadow Creek Funding LLC

                                  By:    /s/ Kelly W. Warnement
                                        ----------------------------------------
                                  Title:     Kelly W. Warnement
                                             Vice President

                                  Sankaty Advisors, LLC as Collateral Manager
                                  for Race Point CLO Limited, as Term Lender

                                  By:    /s/ Diane J. Exeter
                                        ----------------------------------------
                                  Name:      Diane J. Exeter
                                  Title:     Managing Director
                                             Portfolio Manager

                                  Sankaty High Yield Partners III, L.P.

                                  By:    /s/ Diane J. Exeter
                                        ----------------------------------------
                                  Name:      Diane J. Exeter
                                  Title:     Managing Director
                                             Portfolio Manager

                                  Scudder Floating Rate Fund

                                  By:    /s/ Kenneth Weber
                                        ----------------------------------------
                                  Title:     Sr. Vice President

                                  Sequils-Cumberland I, Ltd.
                                  By:   Deerfield Capital management LLC as Its
                                        Collateral Manager

                                  By:    /s/ [signature illegible]
                                        ----------------------------------------
                                  Title:     VP

                                  Toronto Dominion (New York)

                                  By:    /s/ Susan K. Strong
                                        ----------------------------------------
                                  Title:     Susan K. Strong, Vice President

<PAGE>

                                  UBS AG, Stamford Branch

                                  By:    /s/ Patricia O. Kickl
                                        ----------------------------------------
                                  Title:     Patricia O. Kickl
                                             Director
                                             Banking Product Services

                                  By:    /s/ Wilfred V. Saint
                                        ----------------------------------------
                                  Title:     Wilfred V. Saint
                                             Associate Director
                                             Banking Product Services, US

                                  Van Kampen Senior Floating Rate Fund
                                  By:   Van Kampen Investment Advisory Corp.

                                  By:    /s/ Darwin D. Pierce
                                        ----------------------------------------
                                  Title:     Darwin D. Pierce
                                             Executive Director

                                  Van Kampen Senior Income Trust
                                  By:   Van Kampen Investment Advisory Corp.

                                  By:    /s/ Darwin D. Pierce
                                        ----------------------------------------
                                  Title:     Darwin D. Pierce
                                             Executive Director

                                  Van Kampen CLO I, Limited
                                  By:   Van Kampen Investment Advisory Corp. as
                                        Collateral Manager

                                  By:    /s/ Darwin D. Pierce
                                        ----------------------------------------
                                  Title:     Darwin D. Pierce
                                             Executive Director

                                  Van Kampen CLO II, Limited
                                  By:   Van Kampen Investment Advisory Corp. as
                                        Collateral Manager

                                  By:    /s/ Darwin D. Pierce
                                        ----------------------------------------
                                  Title:     Darwin D. Pierce
                                             Executive Director

<PAGE>

                                  Senior Debt Portfolio
                                  By:   Boston Management and Research as
                                        Investment Advisor

                                  By:    /s/ Payton F. Swaffield
                                        ----------------------------------------
                                  Title:     Peyton F. Swaffield
                                             Vice President

<PAGE>

                                  EXHIBIT A TO
            AMENDMENT NO. 1 TO AMENDED AND RESTATED CREDIT AGREEMENT

                                  SCHEDULE III

<TABLE>
<CAPTION>
                                         Revolver                      6/28/02 Revolver
Participant Name                        Commitment      Percentage        Reallocated       Percentage
----------------                        ----------      ----------        -----------       ----------
                                                                          Commitment
                                                                          ----------
<S>                                  <C>               <C>              <C>               <C>
Allied Irish Bank                      4,444,444.44     5.55555556%      4,444,444.44      4.232804229%
American National                      8,888,888.89    11.11111111%      8,888,888.89      8.465608467%
Bank of America, NA                   12,444,444.44    15.55555556%     14,944,444.44     14.232804229%
Comerica Bank                          3,111,111.11     3.88888889%      7,611,111.11      7.248677248%
Credit Suisse First Boston            11,111,111.11    13.88888889%     11,111,111.11     10.582010581%
Fleet National Bank                   11,111,111.11    13.88888889%     13,111,111.11     12.486772486%
Harris Trust & Savings Bank            8,888,888.89    11.11111111%     10,388,888.89      9.894179895%
LaSalle Bank National Association      8,888,888.89    11.11111111%      8,888,888.89      8.465608467%
The Northern Trust Company             4,444,444.45     5.55555555%      5,444,444.45      5.185185190%
UBS AG, Stamford Branch                6,666,666.67     8.33333333%      6,666,666.67      6.349206352%
Credit Lyonnais New York Branch                0.00     0.00000000%     13,500,000.00     12.857142857%

                                     --------------------------------------------------------------------
                                      80,000,000.00   100.00000000%    105,000,000.00     100.00000000%
</TABLE>

<PAGE>

                                  EXHIBIT B TO
            AMENDMENT NO. 1 TO AMENDED AND RESTATED CREDIT AGREEMENT

                                   SCHEDULE IV

<TABLE>
<CAPTION>
                                          Revolver
                                        Outstandings                      6/28/02 Revolver
Participant Name                         (currently     Percentage    Reallocated Outstandings    Percentage
----------------                         ----------     ----------    ------------------------    ----------
                                         LC's only)
                                         ----------
<S>                                     <C>            <C>            <C>                       <C>
Allied Irish Bank                        109,024.11     5.55555556%            83,065.99         4.232804229%
American National                        218,048.23    11.11111111%           166,131.98         8.465608467%
Bank of America, NA                      305,267.52    15.55555556%           279,309.40        14.232804229%
Comerica Bank                             76,316.88     3.88888889%           142,250.51         7.248677248%
Credit Suisse First Boston               272,560.28    13.88888889%           207,664.98        10.582010581%
Fleet National Bank                      272,560.28    13.88888889%           245,044.68        12.486772486%
Harris Trust & Savings Bank              218,048.23    11.11111111%           194,166.76         9.894179895%
LaSalle Bank National Association        218,048.23    11.11111111%           166,131.98         8.465608467%
The Northern Trust Company               109,024.11     5.55555555%           101,755.84         5.185185190%
UBS AG, Stamford Branch                  163,536.17     8.33333333%           124,598.99         6.349206352%
Credit Lyonnais New York Branch**              0.00     0.00000000%           252,312.95        12.857142857%

                                      -------------------------------------------------------------------------
                                       1,962,434.05   100.00000000%         1,962,434.05        100.00000000%
</TABLE>

**This participant is a Purchasing Lender.

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00041-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00041-of-00352.parquet"}]]