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Unassociated Document

    TERMINATION
      AND RELEASE AGREEMENT

     

    This
      TERMINATION AND RELEASE AGREEMENT (this “Agreement”), is entered into as of
      April 16, 2008 by and among APEX BIOVENTURES ACQUISITION CORPORATION, a Delaware
      corporation (“Parent”),
      APEX
      ACQUISITION SUB, INC., a Delaware corporation and wholly-owned subsidiary of
      Parent (“Acquisition
      Sub”)
      and
      DYNOGEN PHARMACEUTICALS, INC., a Delaware corporation (the “Company”).
      Parent, Acquisition Sub and the Company hereinafter collectively referred to
      as
      the “Parties”.

    

    WHEREAS,
      on February 5, 2008, the Parties and the Holder Representatives entered into
      that certain AGREEMENT AND PLAN OF MERGER (the “Merger Agreement”). All
      capitalized terms used herein and not defined, will have the meanings ascribed
      to them in the Merger Agreement; and

     

    WHEREAS,
      the Parties desire to terminate the Merger Agreement on the terms and conditions
      set forth herein.

     

    NOW,
      THEREFORE, in consideration of the premises and the mutual agreements
      hereinafter set forth, the Parties hereby agree as follows:

     

    1.  Termination
      of Merger Agreement.
      In
      accordance with Section 7.1(a) of the Merger Agreement, the Parties acknowledge
      and agree that, effective as of the date hereof, the Merger Agreement is
      irrevocably terminated and of no further force or effect (except for Section
      5.11 of the Merger Agreement which shall survive such termination) and the
      Merger is abandoned.

     

    2.  Confidentiality
      Agreement.
      Notwithstanding anything in this Agreement or in the Merger Agreement to the
      contrary, the Parties acknowledge that the Mutual Non-Disclosure Agreement
      and
      Waiver, dated August 14, 2007, between Parent and the Company (the “Confidentiality
      Agreement”),
      shall
      remain in full force and effect and Acquisition Sub agrees to be bound to the
      terms and conditions of the Confidentiality Agreement as if a party thereto
      to
      the same extent as Parent.

     

    3.  Mutual
      Releases.

     

    (a)  Certain
      Definitions.
      As used
      herein, the following terms shall have the following meanings:

     

    “Associated
      Party”
means,
      with respect to any specified Person, to the extent applicable, such Person’s
      (i) predecessors, successors, executors, administrators, trusts, spouse, heirs
      and estate, (ii) past, present and future assigns, agents and representatives,
      (iii) each entity that such Person has the power to bind (by such Person’s acts
      or signature) or over which such Person directly or indirectly exercises control
      and (iv) each entity of which such Person owns, directly or indirectly, a
      majority of the outstanding equity, beneficial, proprietary, ownership or voting
      interests.

     

    “Claims”
mean
      and include any and all agreements, causes of action, claims, commitments,
      contracts, controversies, covenants, indebtedness, debts, damages, demands,
      disputes, obligations, liabilities, rights and suits of every kind and nature,
      whether in law or equity, whether known or unknown, matured or unmatured,
      accrued or unaccrued, liquidated or unliquidated, asserted or unasserted, fixed
      or contingent, and whether sounding in contract, statute, tort, fraud,
      misrepresentation or other legal theory.

     

    
      
         

      

      
         

        
          

        

      

      
         

      

    

     

    “Company
      Releasee”
means
      the Company, the Company’s present and former directors, officers, employees,
      stockholders, agents and representatives, and the respective Affiliates,
      successors and assigns of each of the foregoing. 

    

    “Parent
      Releasee”
means
      Parent, Acquisition Sub, their respective present and former directors,
      officers, employees, stockholders, agents and representatives, and the
      respective Affiliates, successors and assigns of each of the foregoing.

    

    “Released
      Claims”
means,
      (i) with respect to Section 2(b) below, Claims which Parent, Acquisition Sub
      and/or any of their respective Associated Parties has had or claims to have
      had,
      now has or claims to have, or may in the future have against any Company
      Releasee by reason of any matter, cause or thing whatsoever from the beginning
      of the world through the date hereof, and (ii) with respect to Section 2(c),
      Claims which the Company or the Holder Representatives (or either one of them)
      has had or claims to have had, now has or claims to have, or may in the future
      have against any Parent Releasee by reason of any matter, cause or thing
      whatsoever from the beginning of the world through the date hereof, in each
      case, (A) only to the extent arising out of, or relating to, the Merger
      Agreement, the documents and instruments executed in connection therewith,
      including without limitation, the Key Employee Letter Agreements, and the Merger
      and other transactions contemplated thereby, but (B) excluding Claims arising
      out of, or relating to, the Confidentiality Agreement.

    

    (b)  Release
      by Parent and Acquisition Sub.
      Effective as of the date hereof, each of Parent and Acquisition Sub, on behalf
      of itself and each of its Associated Parties:

     

    (i)  releases
      and forever discharges each Company Releasee of and from each Released Claim;
      

     

    (ii)  waives
      the benefits of, and any rights arising under, any statute or common law
      principle that would provide that the foregoing release does not extend to
      claims that Parent and/or Acquisition Sub does not know or suspect to exist
      at
      the time of executing this Agreement;

     

    (iii)  represents
      and warrants that (A) none of Parent, Acquisition Sub nor any of their
      respective Associated Parties has assigned, transferred, or purported to assign
      or transfer, to any Person any Released Claim, (B) to Parent’s and Acquisition
      Sub’s best knowledge, no other Person or entity has any interest in any of the
      Released Claims, (C) this Agreement has been duly and validly executed and
      delivered by each of Parent and Acquisition Sub, (D) this Agreement is a valid
      and binding obligation of each of Parent and Acquisition Sub, and is enforceable
      against Parent and Acquisition Sub in accordance with its terms, and (E) no
      authorization, instruction, consent or approval of any Person is required to
      be
      obtained by Parent or Acquisition Sub in connection with the execution and
      delivery of this Agreement or the performance hereof (other than the consent
      of
      the Board of Directors of each of Parent and Acquisition Sub, which consent
      has
      been obtained); and

     

    
      
         

      

      
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    (iv)  irrevocably
      covenants to refrain from asserting any claim or demand, or commencing,
      instituting or causing to be commenced, any proceeding of any kind against
      any
      Company Releasee based upon any Released Claim, it being understood that if
      Parent or Acquisition Sub brings any claim, suit, action or manner of action
      against any Company Releasee in administrative proceedings, in arbitration
      or
      admiralty, at law, in equity, or mixed, with respect to any Released Claim,
      then
      Parent or Acquisition Sub, as the case may be, shall indemnify such Company
      Releasee in the amount or value of any final judgment or settlement (monetary
      or
      other) and any related cost (including without limitation reasonable legal
      fees)
      entered against, paid or incurred by the Company Releasee. 

     

    (c)  Release
      by the Company.
      Effective as of the date hereof, the Company, on behalf of itself and each
      of
      its Associated Parties:

     

    (i)  releases
      and forever discharges each Parent Releasee of and from each Released Claim;
      

     

    (ii)  waives
      the benefits of, and any rights arising under, any statute or common law
      principle that would provide that the foregoing release does not extend to
      claims that the Company does not know or suspect to exist at the time of
      executing this Agreement;

     

    (iii)  represents
      and warrants that (A) neither the Company nor any of its Associated Parties
      has
      assigned, transferred, or purported to assign or transfer, to any Person any
      Released Claim, (B) to the Company’s best knowledge, no other Person or entity
      has any interest in any of the Released Claims, (C) this Agreement has been
      duly
      and validly executed and delivered by the Company, (D) this Agreement is a
      valid
      and binding obligation of the Company, and is enforceable against the Company
      in
      accordance with its terms, and (v) no authorization, instruction, consent or
      approval of any Person is required to be obtained by the Company in connection
      with the execution and delivery of this Agreement or the performance hereof
      (other than the consent of the Board of Directors of the Company, which consent
      has been obtained); and

     

    (iv)  irrevocably
      covenants to refrain from asserting any claim or demand, or commencing,
      instituting or causing to be commenced, any proceeding of any kind against
      any
      Parent Releasee based upon any Released Claim, it being understood that if
      the
      Company brings any claim, suit, action or manner of action against any Parent
      Releasee in administrative proceedings, in arbitration or admiralty, at law,
      in
      equity, or mixed, with respect to any Released Claim, then the Company, as
      the
      case may be, shall indemnify such Parent Releasee in the amount or value of
      any
      final judgment or settlement (monetary or other) and any related cost (including
      without limitation reasonable legal fees) entered against, paid or incurred
      by
      the Parent Releasee. 

     

    4.  Continuing
      Waiver Against the Trust.
      For the
      avoidance of doubt, the Company confirms its continuing waiver of all right,
      title, interest or claim of any kind in or to the Trust Account or any monies
      held therein. 

     

    
      
         

      

      
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    5.  Announcements
      and Disclosure.
      As
      promptly as practicable after the execution and delivery of this Agreement
      and,
      in any event, within four Business Days thereof, Parent shall (a) prepare and
      issue a press release, and (b) prepare and file with the SEC a current report
      on
      Form 8-K, in each case, announcing the termination of the Merger Agreement
      (collectively, the “Termination
      Disclosure”),
      in
      each case, subject to the Company’s approval (such approval not to be
      unreasonably delayed or withheld). Further, each Party agrees, on behalf of
      itself and each of its Associated Parties, not to (i) issue or make (or cause
      to
      be issued or made) any press release or public announcement that conflicts
      with
      or is otherwise inconsistent with the Termination Disclosure, except to the
      extent required by applicable Law or the rules of any applicable securities
      exchange, in which case the party proposing to issue or make (or cause to be
      issued or made) such press release or public announcement shall use its
      reasonable best efforts to consult in good faith with the other party before
      issuing or making the same to attempt to agree upon mutually satisfactory text;
      or (ii) make (or cause to be made) any private statement or disclosure that
      conflicts with or is otherwise inconsistent with the Termination Disclosure,
      provided, that, the covenant contained in (ii) above (A) shall not be deemed
      to
      prohibit, limit or restrict private statements or disclosure between or among
      any Party and their respective Associated Parties, and (B) shall be deemed
      to
      apply only to members of the board of directors and corporate officers of the
      respective Parties. 

     

    	6.  	
            Miscellaneous.
              

          

     

    (a)  Entire
      Agreement.
      This
      Agreement states the entire agreement of the Parties concerning the subject
      matter hereof, and supersedes all prior agreements, written or oral, between
      or
      among them concerning such subject matter. 

     

    (b)  Amendments;
      Waivers.
      This
      Agreement may be amended only by the written agreement of each of the Parties,
      and compliance with any provision of this Agreement may be waived only by the
      written agreement of the Party that is adversely affected by such waiver.

     

    (c)  Successors
      and Assigns.
      This
      Agreement shall be binding upon and inure to the benefit of the Parties hereto
      and their respective successors, heirs, personal representatives, legal
      representatives, and permitted assigns. No Party hereto shall assign or
      otherwise transfer this Agreement or any of its rights hereunder, or delegate
      any of its obligations hereunder, without the prior written consent of the
      other
      Parties.

     

    (d)  Severability.
      If any
      term or other provision of this Agreement is invalid, illegal or incapable
      of
      being enforced by any rule of Law or public policy, in any jurisdiction, such
      term or provision shall be ineffective to the extent of such invalidity or
      unenforceability, all other conditions and provisions of this Agreement shall
      nevertheless remain in full force and effect and any such invalidity or
      unenforceability in any jurisdiction shall not invalidate or render
      unenforceable such term or provision in any other jurisdiction.

     

    (e)  Further
      Assurances.
      The
      Parties hereto agree to use their respective reasonable best efforts to take,
      or
      cause to be taken, all action and to do, or cause to be done, all things
      necessary, proper or advisable to consummate and make effective, in the most
      expeditious manner practicable, the transactions contemplated by this
      Agreement.

     

    
      
         

      

      
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    (f)  Governing
      Law; Venue; Waiver of Jury Trial.
      This
      Agreement shall be governed by the Laws of the State of Delaware without giving
      effect to any choice of law or conflict of law provision or rule (whether of
      the
      State of Delaware or any other jurisdiction) that would cause application of
      the
      Laws of any jurisdiction other than the State of Delaware. Each of the Parties
      irrevocably submits to the exclusive jurisdiction of the state courts of
      Delaware and to the jurisdiction of the United States District Court for the
      State of Delaware, for the purpose of any Action arising out of or relating
      to
      this Agreement. Each of the parties to this Agreement consents to service of
      process by delivery pursuant to Section 10.8 of the Merger Agreement and agrees
      that a final judgment in such jurisdiction in any Action shall be conclusive
      and
      may be enforced in other jurisdictions by suit on the judgment or in any other
      manner provided by Law. Each of the Parties waives any right to trial by jury
      with respect to any action related to or arising out of this Agreement or any
      transaction contemplated hereby.

     

    (g)  Counterparts.
      This
      Agreement may be executed in two or more counterparts, any one of which need
      not
      contain the signatures of all Parties, but all of which counterparts when taken
      together will constitute one and the same agreement. Facsimile signatures and
      pdf copies of signature pages, shall constitute original signatures for all
      purposes of this Agreement. This Agreement shall become effective when each
      Party shall have received a counterpart hereof signed by the other
      Parties.
      

     

    (h)  Representation
      by Counsel.
      Each
      Party acknowledges that it has been advised by legal and any other counsel
      retained by such Party in its sole discretion. Each Party acknowledges that
      such
      Party has had a full opportunity to review this Agreement and to negotiate
      this
      Agreement in its sole discretion, without any undue influence by any other
      Party
      or any third party.

     

    (i)  Construction.
      The
      Parties have participated jointly in the negotiations and drafting of this
      Agreement and in the event of any ambiguity or question of intent or
      interpretation, no presumption or burden of proof shall arise favoring or
      disfavoring any Party by virtue of the authorship of any of the provisions
      of
      this Agreement.

     

    (j)  Headings.
      The
      headings of the various sections of this Agreement have been inserted for
      convenience of reference only and shall not be deemed to be a part of this
      Agreement.

     

    (k)  Nouns
      and Pronouns.
      Whenever the context may require, any pronouns used herein shall include the
      corresponding masculine, feminine or neuter forms, and the singular form of
      names and pronouns shall include the plural and vice-versa.

     

    (l)  No
      Waivers.
      No
      waiver by any Party, whether express or implied, of its rights under any
      provision of this Agreement shall constitute a waiver of the Party’s rights
      under such provisions at any other time or a waiver of the Party’s rights under
      any other provision of this Agreement. No failure by any party to take any
      action against any breach of this Agreement or default by another Party shall
      constitute a waiver of the former Party’s right to enforce any provision of this
      Agreement or to take action against such breach or default or any subsequent
      breach or default by the other Party.

     

    {Remainder
      of this page left intentionally blank. Signature page to follow,}

     

    
      
         

      

      
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    NOW,
      THEREFORE, the Parties have executed this Termination and Release Agreement
      as
      of the date first written above.

     

    PARENT:
      

     

    APEX
      BIOVENTURES ACQUISITION CORPORATION

     

    By:
      /s/
      Darrell J. Elliott

    Darrell
      J. Elliott, Chief Executive Officer 

     

    ACQUISITION
      SUB:

     

    APEX
      ACQUISITION SUB, INC.

     

    By:
      /s/
      Darrell J. Elliott 

    Darrell
      J. Elliott, President

     

    COMPANY:

     

    DYNOGEN
      PHARMACEUTICALS, INC.

     

    By:
      /s/
      Lee R. Brettman

    Lee
      R.
      Brettman, Chief Executive Officer

     

    
      
         

      

      
        6AMENDMENT NO

EXHIBIT 4.1

AMENDMENT NO. 2

TO 

AMENDED AND RESTATED RIGHTS AGREEMENT

AMENDMENT NO. 2, dated as of April 15, 2008 (this "Amendment No. 2"), to the Amended and Restated Rights Agreement, dated as of August 4, 2006, between News Corporation, a Delaware corporation (the "Company"), and Computershare Investor Services, LLC (the "Rights Agent"), as amended by Amendment No. 1 thereto, dated as of January 3, 2007 (as amended, the "Rights Agreement").  Capitalized terms used in this Amendment No. 2 but not otherwise defined herein shall have the meanings ascribed to such terms in the Rights Agreement.

WHEREAS, the Company and the Rights Agent entered into the Rights Agreement specifying the terms of the Rights (as defined therein); 

WHEREAS, the Company and the Rights Agent agreed as of January 3, 2007, to amend the Rights Agreement as set forth in Amendment No. 1;

WHEREAS, pursuant to Section 27 of the Rights Agreement, prior to the Distribution Date, the Company and the Rights Agent, shall, if directed by the Company, supplement or amend any provision of the Rights Agreement, without the approval of any holders of Common Stock;

WHEREAS, the Distribution Date has not occurred;

WHEREAS, the Company has delivered to the Rights Agent a certificate stating that this Amendment No. 2 complies with Section 27 of the Rights Agreement;

WHEREAS, the Company and the Rights Agent desire to amend the Rights Agreement in accordance with Section 27 of the Rights Agreement as set forth herein; 

NOW, THEREFORE, in consideration of the premises and mutual agreements set forth in the Rights Agreement and this Amendment, the parties hereby agree as follows: 

	Section 7(a) of the Rights Agreement is hereby amended to read in its entirety:

"Section 7. Exercise of Rights; Purchase Price; Expiration Date of Rights. 

(a) Subject to Section 7(e) hereof, at any time after the Distribution Date the registered holder of any Rights Certificate may exercise the Rights evidenced thereby (except as otherwise provided herein including, without limitation, the restrictions on exercisability set forth in Section 9(c), Section 11(a)(iii) and Section 23(a) hereof) in whole or in part upon surrender of the Rights Certificate, with the form of election to purchase and the certificate on the reverse side thereof duly executed, to the Rights Agent at the office of the Rights Agent designated for such purpose, together with payment of the aggregate Purchase Price with respect to the total number of one one-thousandths of a share of Preferred Stock (or other securities, cash or other assets, as the case may be) as to which such surrendered Rights are then exercisable, and an amount equal to any tax or charge required to be paid under Section 9(e), at or prior to the earlier of (i) 5:00 P.M., New York City time, on April 15, 2008 (the "Final Expiration Date"), or (ii) the time at which the Rights are redeemed or exchanged as provided in Section 23 and Section 24 hereof (the earlier of clauses (i) and (ii) being referred to herein as the "Expiration Date")."

	The Exhibits to the Rights Agreement shall be deemed restated to reflect this Amendment No. 2, mutatis mutandis.
	The term "Agreement" as used in the Rights Agreement shall be deemed to refer to the Rights Agreement as amended hereby. 
	This Amendment shall be effective upon execution by the parties hereto and, except as set forth herein, the Rights Agreement shall remain in full force and effect and shall be otherwise unaffected hereby.  Notwithstanding anything to the contrary herein, each of the Company and the Rights Agent hereby acknowledges and agrees that at 5:00 P.M., New York City time on the Final Expiration Date (as amended hereby), the Rights Agreement shall terminate and be of no further force and effect.
	This Amendment may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument.

IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be duly executed as of the day and year first above written. 

	 	 	 
	
Attest:
	 	
NEWS CORPORATION

	 	 	 
	
By: 
	
/s/ Laura O'Leary
	 	
By: 
	
/s/ Lawrence A. Jacobs

	
Name:  Laura O'Leary
	 	
Name:  Lawrence A. Jacobs

	
Title:  Corporate Secretary
	 	
Title:  Senior Executive Vice

	 	 	
                   President and Group     

	 	 	
                   General Counsel

	 	 	 
	
Attest:
	 	
COMPUTERSHARE INVESTOR SERVICES, LLC

	 	 	 
	
By: 
	
/s/ Karen A. Carlson
	 	
By: 
	
/s/ Dennis V. Moccia

	
Name:  Karen A. Carlson  
	 	
Name:  Dennis V. Moccia

	
Title:  Paralegal
	 	
Title:  Managing Director

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