Document:

Agreement with Allen's TV Cable Service, Inc.

 Exhibit 10.21 
 

 
 Master Services Agreement 
 This Master Service Agreement (“Agreement”) is made this 1 day of February 2008 between IPtimize, Inc and ALLEN’S TV CABLE SERVICE, INC. (“Customer”). This Agreement provides the
general terms and conditions applicable to Customer’s purchase of communications services (“Service”) from IPtimize, Inc. 
 ARTICLE 1.
ORDERS FOR AND DELIVERY OF SERVICE 
 1.1 Submission and Acceptance of Customer Order(s). Customer may submit requests for Service in a
form designated by IPtimize (“Customer Order”). The Customer Order shall contain the duration for which Service is ordered (“Service Term”) and pricing for Service; Upon expiration of the initial Service Term Service will
continue on a month to month basis at the then current IPtimize rates. IPtimize will notify Customer on a regular and timely basis (in writing or electronically) of either its acceptance or rejection of each Customer Order received along with a
proposed date by which IPtimize will have provisioned Service for said request (the “Customer Commit Date”); renewal Customer Orders will be accepted by IPtimize’s continuation of Service. If Customer submits Customer Orders
electronically, Customer shall assure that any passwords or access devices are available only to those having authority to submit Customer Orders. 
 1.2
Credit Approval and Deposits. Customer will provide IPtimize with credit information as reasonably requested. IPtimize may require Customer to make a deposit as a condition of IPtimize’s acceptance of any Customer Order or
continuation of: a) any usage-based Service; or b) any non-usage based Service where Customer fails to timely make any payment due hereunder or IPtimize reasonably determines that Customer has had an adverse change in financial condition based on an
exhibited failure to make payments when due. Deposits based on 1.2 will not exceed one months’ estimated charges for Service and will be due upon IPtimize’s written request. When Service is discontinued, the deposit will be credited to
Customer’s account and the balance, if any will be refunded. 
 1.3 Customer Premises. If access to non- IPtimize facilities is required
for the installation, maintenance or removal of IPtimize equipment, Customer shall, at its expense, secure such right of access and shall arrange for the provision and maintenance of power and HVAC as needed for the proper operation of such
equipment. 
 1.4 Scheduled Maintenance and Local Access. Scheduled maintenance will not normally result in Service interruption. If scheduled
maintenance requires Service interruption, IPtimize will (i) provide Customer 7 days’ prior written notice, (ii) work with Customer to try to minimize Service interruptions and (iii) use commercially reasonable efforts to perform
such maintenance between midnight and 6:00 a.m. local time. If third party provided local access services are obtained by Customer in conjunction with a Customer Order, Customer will: (i) provide IPtimize with circuit facility information, firm
order commitment information and necessary design layout records to enable cross-connects to IPtimize Service(s) (such cross connects being provided by IPtimize subject to applicable charges), (ii) cooperate with IPtimize (including providing
necessary LOA’s) in connection with IPtimize circuit grooming, and (iii) where a related Service is disconnected or terminated, promptly provide IPtimize a written disconnection firm order commitment from the relevant third party provider.

  

					
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 ARTICLE 2. BILLING AND PAYMENT 
 2.1 Commencement of Billing. IPtimize will deliver written or electronic notice (a “Connection Notice”) to Customer upon installation of Service, at which time billing will commence
(“Service Commencement Date”), regardless of whether Customer is prepared to accept delivery of Service. If Customer notifies IPtimize within 3 days after delivery of the Connection Notice that Service is not functioning properly (and such
Service is not functioning properly), IPtimize will correct any deficiencies and, upon Customer’s request, credit Customer’s account in the amount of 1/30 of the applicable MRC for each day the Service did not function properly.

 2.2 Payment of Invoices and Disputes. Invoices are delivered monthly and due 30 days after the date of invoice. Fixed charges are billed in
advance and usage-based charges are billed in arrears. Billing for partial months is prorated. Past due amounts bear interest at 1.5% per month or the highest rate allowed by law (whichever is less). Customer is responsible for all charges
respecting the Service, even if incurred as the result of unauthorized use, if such unauthorized use was due to the fault of Customer. If Customer reasonably disputes an invoice, Customer must pay the undisputed amount and submit written notice of
the disputed amount (with details of the nature of the dispute and the Services and invoice(s) disputed). Disputes must be submitted in writing within 90 days from the date of the invoice or, if not readily apparent from the invoice, 90 days from
the date of the Customer’s invoice to its end user. If the dispute is resolved against Customer, Customer shall pay such amounts from the date originally due. 
 2.3 Taxes and Fees. Except for taxes based on IPtimize’s net income, Customer will be responsible for reimbursement of all taxes and fees, including USF (Universal Service Fund) fees that arise in any jurisdiction,
including value added, consumption, sales, use, gross receipts, foreign withholding (which will be grossed up), excise, access, bypass, franchise or other taxes, fees, duties, charges or surcharges imposed on or incident to the provision, sale or
use of Service (whether imposed on IPtimize or any affiliate of IPtimize). If such taxes, fees or charges are imposed by any jurisdiction with authority on IPtimize as a direct result of the Services provided by this Agreement to Customer, IPtimize
shall notify and provide Customer with an itemized schedule of all such taxes or fees in writing as soon as is reasonably possible, but not less than 45 days before initiating such pass through to Customer. Such charges may be shown on invoices as
cost recovery fees. Charges for Service are exclusive of taxes. Customer may present IPtimize a valid exemption certificate and IPtimize will give effect thereto prospectively. IPtimize shall timely provide to Customer evidence that any such
reimbursed taxes or fees paid to IPtimize by Customer were subsequently paid to satisfy any and all obligations due to the appropriate authority or taxing district . Customer shall not be responsible or assume any obligation to pay any liens,
penalties, interest or late fees that may be imposed or incurred due to the failure of IPtimize to timely pay any such taxes or fees when due. 
 2.4
Regulatory and Legal Changes. If any change in applicable law, regulation, rule or order materially affects delivery of Service, the parties will negotiate appropriate changes to this Agreement. If the parties are unable to reach
agreement within 30 days after IPtimize’s delivery of written notice requesting renegotiation: (a) IPtimize may, upon thirty (30) days written notice, pass any increased costs relating to delivery of Service through to Customer and
(b) if IPtimize does so, Customer may terminate the affected Service without termination liability by delivering written notice to IPtimize within thirty (30) days of receipt of the IPtimize notice. 
  

	2.5	Cancellation and Termination Charges. 

 (A) Customer may
cancel a Customer Order (or portion thereof) prior to delivery of the Connection Notice upon written notice to IPtimize identifying the affected Customer Order and Service. If Customer does so, Customer shall pay IPtimize a cancellation charge

  

					
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equal to the sum of: (i) for “off-net” Service, third party termination charges for the cancelled Service; (ii) for “on-net”
Service, 1 month’s monthly recurring charges for the cancelled Service; (iii) the non-recurring charges for the cancelled Service; and (iv) IPtimize’s out of pocket costs (if any) incurred in constructing facilities necessary for
Service delivery. 
 (B) Customer may terminate Service after delivery of the Connection Notice upon 30 days’ written notice to IPtimize identifying the
terminated Service. If Customer does so without cause, or if Service is terminated by IPtimize as the result of an uncured default by Customer, Customer shall pay IPtimize a termination charge equal to the sum of: (i) all unpaid amounts for
Service provided through the date of termination; (ii) 100% of the remaining monthly recurring charges for months 1-12 of the Service Term; and (iii) 50% of the remaining monthly recurring charges for month 13 through the end of the
Service Term. The parties agree that the charges in this Section are a genuine estimate of IPtimize’s actual damages and are not a penalty. The termination charges shall be Customer’s sole liability and Ipitimize’s sole and exclusive
remedy for termination of the service by Customer without cause or termination by iPtimize as the result of an uncured default by Customer. 
 (C) Customer
may terminate Service as “Hosted” by IPtimize and convert to a “Managed” level of Service with IPtimize without incurring any termination charges or any other fees. 
 (D) This Agreement may be terminated by either Party upon notice to the other if any law, rule or regulation is adopted or passed by an authority with such jurisdiction that would make it unlawful to perform its
obligations under this Agreement. The effective date of such termination shall be no earlier than the date on which any such law, rule or regulation will result in the performances herein to be declared unlawful; provided that the Parties, in a
commercially reasonable manner, have made a good faith effort to modify this Agreement so that the performance of the obligations hereunder are no longer declared unlawful. 
 (E) Upon termination of Service after delivery of the Connection Notice, IPtimize acknowledges and agrees not to seek or claim ownership of telephone numbers assigned and utilized by Subscribers of Customer in
connection with this Agreement. 
 ARTICLE 3. DEFAULT 
 If (A) Customer fails to make any payment when due and such failure continues for Ten (10) business days after written notice from IPtimize, or (B) either party breaches or fails to observe or perform any other material term
of this Agreement and such failure continues for 30 days without cure after written notice from the other party, then the non-defaulting party may: (i) terminate this Agreement and/or any Customer Order, in whole or in part, and immediately be
relieved of any further obligations or liabilities as pertains to this Agreement and/or (ii) subject to Section 4.1, pursue any remedies it may have at law or in equity. 
 ARTICLE 4. LIABILITIES AND SERVICE LEVELS 
 4.1 No Special Damages. Neither party shall be liable
for any damages for lost profits, lost revenues, loss of goodwill, loss of anticipated savings, loss of data or cost of purchasing replacement services, or any indirect, incidental, special, consequential, exemplary or punitive damages arising out
of the performance or failure to perform under this Agreement or any Customer Order. 
  

					
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 4.2 Disclaimer of Warranties. Other than the Service Level commitments described in Section 4.3
and as set forth in this Section 4.2, IPtimize MAKES NO WARRANTIES OR REPRESENTATIONS, EXPRESS OR IMPLIED, EITHER IN FACT OR BY OPERATION OF LAW, STATUTORY OR OTHERWISE, INCLUDING WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR USE,
EXCEPT THOSE EXPRESSLY SET FORTH IN THIS AGREEMENT OR ANY APPLICABLE SERVICE SCHEDULE. BOTH PARTIES REPRESENT AND WARRANT THAT (i) THEY HAVE BEEN DULY ORGANIZED AND ARE VALIDLY EXISTING IN GOOD STANDING UNDER THE LAWS OF THE JURISDICTION IN
WHICH THEY WERE ORGANZED; (ii) THEY HAVE THE FULL RIGHT, POWER AND AUTHORITY TO EXECUTE, DELIVER AND PERFORM THEIR OBLIGATIONS UNDER THIS AGREEMENT, (iii) THE EXECUTION AND PERFORMANCE OF THIS AGREEMENT DOES NOT NOR WILL NOT VIOLATE ANY
APPLICABLE EXISTING RULES, REGULATION, STATUTES OR ORDERS OF COURT FROM ANY NATIONAL, STATE OR LOCAL AGENCY, COURT OR BODY OR ANY CONTRACT OR OTHER AGREEMENT TO WHICH THEY ARE A SUBJECT; (iv) TO THE BEST OF THEIR KNOWLEDGE, NO THIRD PARTY
CLAIMS WILL PREVENT THEM FROM FULFULLING THEIR OBLIGATIONS UNDER THIS AGREEMENT; (v) UPON EXECUTION, THIS AGREEMENT CONSTITUTES A LEGAL, VALID AND BINDING OBLIGATION BETWEEN THE PARTIES; and (VI) THEY HAVE ANY NECESSARY REGULATORY APPROVAL TO
PROVIDE THE SERVICES CONTRACTED FOR . 
 4.3 Service Levels. The “Service Level” commitments applicable to the Services are found in
IPtimize’s Service Schedules for each Service. If IPtimize does not achieve a Service Level, a credit will be issued to Customer as set forth in the applicable Service Schedule upon Customer’s request. IPtimize’s maintenance log and
trouble ticketing systems will be used for calculating any Service Level events. To request a credit, Customer must notify in writing, its IPtimize Account Manager or deliver a written request (with sufficient detail necessary to identify the
affected Service) within 60 days after the end of the month in which the Service affecting event occurred. In no event shall the total credits issued to Customer exceed the non-recurring and monthly recurring charges for the affected Service for
that month. Customer’s sole remedies for any outages, failures to deliver or defects in Service are contained in the Service Levels applicable to the affected Service. 
 4.4 Right of Termination for Installation Delay. In lieu of any Service Level credits for installation delays, if IPtimize’s installation of Service is delayed for more than 30 business days beyond
the Service Commencement Date, Customer may terminate the affected Service upon written notice to IPtimize and without payment of any applicable termination charge, provided such written notice is delivered prior to IPtimize delivering a Connection
Notice for the affected Service. This Section shall not apply to any Service where IPtimize has agreed to construct network facilities in or to a new location not previously served by IPtimize. 
 ARTICLE 5. GENERAL TERMS 
 5.1 Force Majeure.
Neither party shall be liable, nor shall any credit allowance, damages or other remedy be extended, for any failure of performance, delays, losses, destruction or equipment due to causes beyond such party’s reasonable control caused or
occasioned by or due to fire, wind, flood, water, ice, hail, acts of God or Nature, war, terrorism, labor dispute or shortages, power failures, cable cuts, civil disturbances, governmental actions, equipment or supply shortages, explosions,
hurricanes, lack of transportation or omissions by third parties, each but not limited to a (“force majeure event”). In the event IPtimize is unable to deliver Service as a result of a force majeure event, IPTIMIZE shall as soon as is
reasonably possible, notify Customer of such event along with an estimated duration the event will exist and exercise good faith efforts to minimize and remedy such event. Customer shall not be obligated to pay IPtimize for the affected Service for
so long as IPtimize is unable to deliver the affected Service. Force majeure events along with scheduled maintenance under section 1.4 shall be considered “Excused Outages.” 
  

					
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 5.2 Assignment and Resale. Customer may not assign its rights or obligations under this Agreement or
any Customer Order without the prior written consent of IPtimize, which will not be unreasonably withheld. This Agreement shall apply to any permitted transferees or assignees. Customer may resell or otherwise provide the Service to third parties or
use the Services in connection with goods or services provided by Customer to third parties (“Customer Provided Services“) provided that Customer shall indemnify, defend and hold IPtimize and its affiliates harmless from any claims arising
from or related to any Customer Provided Services. If Customer resells telecommunications services, Customer certifies that it has filed all required documentation and will at all relevant times have the requisite authority with appropriate
regulatory agencies respecting the same. Nothing in this Agreement, express or implied, is intended to or shall confer upon any third party any right, benefit or remedy of any nature whatsoever under or by reason of this Agreement. 
 5.3 Affiliates. Service may be provided to Customer pursuant to this Agreement by an affiliate of IPtimize, but IPtimize shall remain responsible to
Customer for the delivery and performance of the Service. Customer’s affiliates may purchase Service pursuant to this Agreement. Customer shall be jointly and severally liable for all claims and liabilities related to Service ordered by any
Customer affiliate, and any default under this Agreement by any Customer affiliate shall also be a default by Customer. 
 5.4 Notices. All
notices shall be in writing and sufficient and received if delivered in person, or when sent via facsimile, pre-paid overnight courier, electronic mail (if an e-mail address is provided below) or sent by U.S. Postal Service (or First Class
International Post (as applicable)), addressed as follows: 
  

			
	IF TO IPtimize:	  	IF TO CUSTOMER:
		
	 IPtimize, Inc
	  	ALLEN’S TV CABLE SERVICE, INC.
		
	 2135 S. Cherry Street
	  	P. O. Box 2643
		
	 Suite 200
	  	Morgan City, LA 70381-2643
		
	 Denver, CO 80222
	  	
		
	Attn: Clint Wilson or President	  	 Attn: Jeffrey A. Price or

		
		  	Attn: Gregory A. Price, President

 Either party may change its notice address upon notice to the other party. All notices shall be deemed to have
been given on (i) the date delivered if delivered personally, by facsimile or e-mail (one business day after delivery if delivered on a weekend or legal holiday), (ii) the business day after dispatch if sent by overnight courier, or
(iii) the third business day after posting if sent by U.S. Postal Service (or other applicable postal delivery service). 
 5.5 Acceptable Use
Policy; Data Protection. If applicable, Customer‘s use of Service shall comply with IPtimize‘s reasonable Acceptable Use Policy and Privacy Policy, as communicated in writing to Customer from time to time. IPtimize may transfer,
process and store billing and utilization data and other data necessary for operation of its network and for the performance of its obligations under this Agreement. Customer consents that IPtimize may (i) transfer, store and process such data
in the United States; and (ii) use such data only for its own internal purposes to perform the services contracted for by Customer. At no time will any Customer data be disclosed to any third parties without prior written consent of the two
parties to this Agreement. 
 As utilized herein, Data shall mean any confidential information, proprietary plans, technological or business information
(including trade technology, secrets, intellectual property, marketing, summaries, mailing lists, subscriber data or information, reports, or any other information regarding Customer and / or its subscribers, whether oral, written or electronically
obtained or otherwise disclosed, reproduced, transmitted or received. 
  

					
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 5.6 Intellectual Property and Publicity. Neither party is granted a license or other right (express,
implied or otherwise) to use any trademarks, copyrights, service marks, trade names, patents, trade secrets or other form of intellectual property of the other party or its affiliates without the express prior written authorization of the other
party. Each party will at all times remain the sole owner of all intellectual property it rightfully owns as of the effective date of this Agreement as well as any intellectual property rights it may acquire or develop during the Term of this
Agreement. Neither party shall issue any press release nor make any other public statement relating to this Agreement, except as may be required by law or agreed between the parties in writing. Any information or documentation disclosed between the
parties during the performance of this Agreement (including this Agreement) shall be subject to the terms and conditions of the applicable non-disclosure agreement then in effect between the parties and which may afford the aggrieved Party the right
to terminate this Agreement and / or seek immediate injunctive relief or any other legal rights and remedies available. 
 5.7 Governing Law;
Amendment. This Agreement shall be governed and construed in accordance with the laws of the State of Colorado, without regard to its choice of law rules. It also may be governed by any governmental authority, court, tribunal, agency,
regulatory, administrative, judicial agency, commission or organization of any subdivision, branch or department of any of the foregoing. This Agreement, including any Service Schedule(s) and Customer Order(s) executed hereunder, constitutes the
entire and final agreement and understanding between the parties with respect to the Service and supersedes all prior agreements relating to the Service. This Agreement may only be modified or supplemented by an instrument executed by an authorized
representative of each party. No failure by either party to enforce any right(s) hereunder shall constitute a waiver of such right(s). 
 5.8
Relationship of the Parties. The relationship between Customer and IPtimize shall not be that of partners, agents, or joint ventures for one another, and nothing contained in this Agreement shall be deemed to constitute a partnership or
agency agreement between them for any purposes. 
 5.9 Most Favored Nations Provision. Customer shall receive and IPtimize shall provide Most
Favored Nations Protection in Pricing, Services, Equipment and Training at all times during the Term for any similar-sized Customers offering Voice Services. IPtimize shall notify Customer of any favorable pricing or provisions it may offer or grant
to another customer and offer such to Customer to be included in this Agreement. 
 6.0 Event of Insolvency. This Agreement may immediately be
terminated by Customer upon written notice to IPtimize in the event that IPtimize makes an assignment for the benefit of creditors, dissolves or liquidates, has a receiver or trustee appointed over it or any of its assets, is declared insolvent or
bankrupt, or a voluntary or involuntary petition is filed in any court of competent jurisdiction under the applicable bankruptcy laws, including for liquidation or reorganization, and such petition is not withdrawn within sixty (60) calendar
days after filing. 
 6.1 Counterparts. This Agreement may be executed in one or more counterparts, all of which taken together shall
constitute one and the same instrument. Facsimile signatures shall be sufficient to bind the parties to this Agreement. 
  

					
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	IPTIMIZE, INC. (“IPtimize)	 		 	ALLEN’S TV CABLE SERVICE, INC. (“Customer”)
					
	By	 	/s/ Clinton J. Wilson	 		 	By	 	/s/ Gregory A. Price
	Name Clinton J. Wilson	 		 	Name Gregory A. Price
	Title President	 		 	Title President
	Date March 25, 2008	 		 	Date March 25, 2008

  

					
		  	CONFIDENTIAL	  	Page 7 of 7Waiver and Amendment Agreement

 Exhibit 4. 3B 
 JAZZ PHARMACEUTICALS, INC. 
 WAIVER AND AMENDMENT AGREEMENT 
 THIS WAIVER AND AMENDMENT AGREEMENT (the
“Agreement”) is made effective as of March 12, 2008 (the “Effective Date”), by and among JAZZ PHARMACEUTICALS, INC., a Delaware corporation (the
“Company”), and the undersigned Holders (the “Consenting Holders”). 
 RECITALS

 WHEREAS, the Company and the Investors are parties to that certain Third Amended and Restated Investor Rights
Agreement made effective as of June 6, 2007 (the “Investor Rights Agreement”). 
 WHEREAS,
the Consenting Holders acknowledge that the Company expects to enter into a Registration Rights Agreement in substantially the form attached hereto as Exhibit A (the “Registration Rights Agreement”) with certain
purchasers (the “Purchasers”) of senior secured notes and warrants to purchase shares of the Company’s Common Stock (the “Warrant Shares”) pursuant to the terms of a Senior Secured Note and
Warrant Purchase Agreement by and among the Company, JPI Commercial, LLC and the Purchasers (the “Note and Warrant Purchase Agreement”). 
 WHEREAS, the Consenting Holders acknowledge that pursuant to the terms of the Registration Rights Agreement, the Company will be obligated to prepare and file a registration statement (the
“Resale Registration Statement”) under the Securities Act of 1933, as amended (the “Securities Act”), registering the resale of the Warrant Shares from time to time by the Purchasers (or any subsequent
transferees or assignees thereof). As used in this Agreement, (i) the term “Warrant Shares” also includes any shares of the Company’s Common Stock issued as (or issuable upon the conversion or exercise of any
warrant, right or other security that is issued as) a dividend or other distribution with respect to, or in exchange for, or in replacement of, the Warrant Shares; and (ii) the term “Resale Registration Statement” also
includes (A) any registration statement filed by the Company under the Securities Act pursuant to the terms of the Registration Rights Agreement and (B) any amendments or supplements to any of such registration statements. 
 WHEREAS, pursuant to Section 4 of the Investor Rights Agreement, the Holders have under certain circumstances the right to be
notified if the Company decides to Register any of its Common Stock and to include certain Registrable Securities held by such Holders in such Registration (and any related qualification under Blue Sky laws or other compliance), and in any
underwriting involved therein (the “Piggyback Registration Rights”). 
 WHEREAS, pursuant to
Section 15.5 of the Investor Rights Agreement, the Company and the Consenting Holders (for and on behalf of all Holders and all Investors) wish to (i) amend the Investor Rights Agreement as set forth below; and (ii) waive each of
(A) the Piggyback Registration Rights in connection with the filing of the Resale Registration Statement and any offerings made pursuant thereto and (B) the provisions of Section 10 of the Investor Rights Agreement with respect to the
entering into of the Registration Rights Agreement by the Company and the grant to the Purchasers of Registration rights pursuant thereto. 
 WHEREAS, the Consenting Holders are holders of at least 60% of the Registrable Securities held by all Holders and, together with the Company, have the right, pursuant to Section 15.5 of the Investor Rights
Agreement, to amend the Investor Rights Agreement and to waive certain provisions thereof. 
  

 1 

 NOW, THEREFORE, in consideration of the mutual agreements, covenants
and considerations contained herein, the Company and the Consenting Holders agree as follows: 
 AGREEMENT 
  

	 	1.	WAIVERS. 

 1.1
The Consenting Holders hereby waive, for and on behalf of all Holders and all Investors, the provisions of Section 10 of the Investor Rights Agreement with respect to the entering into of the Registration Rights Agreement by the Company and the
grant to the Purchasers of Registration rights pursuant thereto. In furtherance of the foregoing, the Consenting Holders hereby provide, for and on behalf of all Holders and all Investors, express written consent to the entering into by the Company
of the Registration Rights Agreement and to the consummation by the Company of the transactions contemplated thereby, including but not limited to the grant of Registration rights to the Purchasers and the filing of the Resale Registration Statement
pursuant thereto. 
 1.2 The Consenting Holders hereby further waive, for and on behalf of all Holders and all
Investors, (i) any and all Piggyback Registration Rights in connection with the filing of, and any offerings made pursuant to, the Resale Registration Statement and (ii) any rights to any notices with respect to the foregoing under the
Investor Rights Agreement. 
 1.3 The foregoing waivers in Sections 1.1 and 1.2 are irrevocable and shall be effective
with respect to each Holder and each Investor, as well as all affiliates, successors, heirs, executors, administrators and assigns of each such Holder and Investor. 
  

	 	2.	AMENDMENTS TO INVESTOR RIGHTS AGREEMENT. 

 2.1 Section 1.1. Section 1.1 of the Investor Rights Agreement is hereby amended and restated to read in full as
follows: 
 “1.1 “Affiliate” shall mean, with respect to any Person, a Person directly or indirectly controlling,
controlled by, or under common control with, such Person; provided, however, that, except for purposes of Section 11.2, no Series BB Holder shall be considered an Affiliate of any other Person except to the extent, and only to the
extent, that such Series BB Holder holds shares of Common Stock issued upon conversion of the Convertible Securities other than shares of Common Stock issued upon exercise of the Series BB Warrants.” 
 2.2 Section 1.19. Section 1.19 of the Investor Rights Agreement is hereby amended and restated to read in full as
follows: 
 “1.19 “Registrable Securities” shall mean (i) any Common Stock now owned or hereafter acquired
by a Manager, (ii) any Common Stock issued upon conversion of the Convertible Securities, (iii) any Common Stock issued upon exercise of the Series BB Warrants, and (iv) any Common Stock issued (or issuable upon conversion or exercise
of any warrant, right or other security which is issued) upon stock dividends, subdivisions, stock splits, recapitalization, merger or other distributions with respect to, or in exchange for, or in replacement of, such securities identified in
clauses (i), (ii) and (iii) and this clause (iv), provided, however, that no shares of Common Stock shall be deemed Registrable Securities for purposes of this Agreement to the extent that such shares of Common Stock
(A) have been sold to the public through a Registration Statement or 

  

 2 

 
pursuant to Rule 144; (B) have been sold, transferred or otherwise disposed by a person in a transaction in which its rights under this Agreement were
not assigned; or (C) are held by a Holder or Investors whose rights to cause the Company to register securities pursuant to this Agreement have terminated in accordance with Section 6 of this Agreement.” 
 2.3 Section 1.23. Section 1.23 of the Investor Rights Agreement is hereby amended and restated to read in full as
follows: 
 “1.23 “Series BB Holder” means a holder of (i) warrants originally exercisable for shares of the
Company’s Series BB Preferred Stock, which such warrants (A) were originally issued pursuant to a Senior Secured Note and Warrant Purchase Agreement, dated June 24, 2005, by and among the Company and certain of the Investors and
(B) automatically became exercisable for shares of Common Stock in connection with the Initial Public Offering (the “Series BB Warrants”); or (ii) shares of Common Stock issued upon exercise of the Series BB
Warrants.” 
 2.4 Section 1.24. Section 1.24 of the Investor Rights Agreement is hereby amended
and restated to read in full as follows: 
 “1.24 “Special Registration Statement” shall mean (i) any
registration statement relating to any employee benefit plan; (ii) with respect to any corporate reorganization or transaction under Rule 145 of the Securities Act, any registration statement related to the issuance or resale of securities
issued in such a transaction; (iii) any registration statement related to stock issued upon conversion of debt securities; (iv) any Registration effected pursuant to the terms of the Registration Rights Agreement; or (v) any WKSI
Shelf Registration Statement that the Company’s Board of Directors shall, in its sole discretion, designate as a “Special Registration Statement” for purposes of this Agreement.” 
 2.5 Section 1.26. Section 1.26 is hereby added to the Investor Rights Agreement and shall read in full as follows:

 “1.26 “Purchase Agreement” means that certain Stock Purchase Agreement, dated as of January 27, 2004, by
and among the Company and certain of the Investors, as amended from time to time in accordance with the terms thereof.” 
 2.6 Section 1.27. Section 1.27 is hereby added to the Investor Rights Agreement and shall read in full as follows: 
 “1.27 “Registration Rights Agreement” means that certain Registration Rights Agreement, dated as of March 17, 2008, by and among the Company and the purchasers listed on Schedule A thereto, as the same may
be amended from time to time in accordance with the terms thereof.” 
 2.7 Section 12. Section 12 of the
Investor Rights Agreement is hereby amended and restated to read in full as follows: 
 “12. Market Standoff. Each Holder
hereby agrees that, if so requested by the Company and the Underwriter’s Representative (if any), such Holder shall not sell, make any short sale of, loan, grant any option for the purchase of, or otherwise transfer or dispose of any
Registrable Securities or other securities (except for the Warrant Shares and the warrants 

  

 3 

 
issued pursuant to the Note and Warrant Purchase Agreement) of the Company (“Market Standoff”) without the prior written consent of the Company and
the Underwriter’s Representative for such period of time commencing with the date the Company provides notice to the Holders of a proposed follow-on offering pursuant to Section 4.1 or otherwise (including Registrations initiated pursuant
to Section 3) and ending 90 days after the effective date of the Registration Statement with respect to the follow-on offering or, in the event of a shelf registration, the date of the prospectus supplement for such follow-on offering, as may
be requested by the Underwriter’s Representative; provided, however, that a Holder shall not be required to agree to a Market Standoff for a period of time that commences less than 30 days after the expiration of another period of
time during which the Holder has agreed to a Market Standoff. The obligations of the Holders under this Section 12 shall be conditioned upon similar agreements being in effect with each other stockholder who is an officer or director. In order
to enforce the covenants set forth in this Section 12, the Company may impose stop-transfer instructions with respect to the securities of the Holder (and the securities of every other Person subject to the restrictions in this
Section 12).” 
  

	 	3.	MISCELLANEOUS. 

 3.1 Defined Terms. Capitalized terms not otherwise defined herein shall have the meanings ascribed to them in the Investor Rights Agreement. 
 3.2 Full Power and Authority. Each Consenting Holder represents and warrants to the Company that (i) such Consenting Holder
has the full right, power and authority to execute and deliver this Agreement, and (ii) this Agreement has been duly executed and delivered by such Consenting Holder and constitutes the legal, valid and binding obligation of such Consenting
Holder enforceable in accordance with its terms, except (A) as such enforcement is limited by bankruptcy, insolvency or other similar laws affecting the enforcement of creditors’ rights generally and (B) for limitations imposed by
general principles of equity. 
 3.3 Effect of Agreement. Except as modified by the terms of this Agreement, the terms
and provisions of the Investor Rights Agreement shall remain in full force and effect. Other than as stated in this Agreement, this Agreement shall not operate as a waiver of any condition or obligation imposed on the parties under the Investor
Rights Agreement. In the event of any conflict, inconsistency, or incongruity between any provision of this Agreement and any provision of the Investor Rights Agreement, the provisions of this Agreement shall govern and control. This Agreement shall
not be changed or modified orally, but only by an instrument in writing signed by the parties hereto. 
 3.4 Governing
Law. This Agreement shall be governed by, and construed in accordance with, the laws of the State of California excluding those laws that direct the application of the laws of another jurisdiction. 
 3.5 Successors and Assigns. The provisions hereof shall inure to the benefit of, and be binding upon, the successors, assigns,
heirs, executors and administrators of the parties hereto and each Holder and Investor, and shall be enforceable by the Company or any Holder or Investor. 
 3.6 Counterparts. This Agreement may be executed in several counterparts, each of which shall constitute an original and all of which, when taken together, shall constitute one instrument. 
  

 4 

 3.7 Certain Confidential Information. Certain of the information contained in this
Agreement is confidential and has not been publicly disclosed by the Company, including the transactions contemplated by the Note and Warrant Purchase Agreement and the contemplated filing of the Resale Registration Statement pursuant to the terms
of the Registration Rights Agreement (the “Confidential Information”). Accordingly, each of the undersigned Holders agrees to maintain the Confidential Information in confidence until such time as the Confidential Information
has been publicly disclosed by the Company. 
 [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK] 
  

 5 

 IN WITNESS WHEREOF, the undersigned have executed
this AGREEMENT effective as of the Effective Date. 
  

			
	
	COMPANY:
	
	JAZZ PHARMACEUTICALS, INC.
		
	Signature:	 	/s/ Carol A. Gamble
	Print Name:	 	Carol A. Gamble
	Title:	 	Sr. Vice President and General Counsel

 SIGNATURE PAGE TO 
 WAIVER AND AMENDMENT AGREEMENT 

 IN WITNESS WHEREOF, the undersigned have executed
this AGREEMENT effective as of the Effective Date. 
 INVESTORS: 
  

			
	KKR JP LLC
		
	Signature:	 	/s/ Michael W. Michelson
	Print Name:	 	Michael W. Michelson
	Title:	 	 
	
	KKR JP III LLC
		
	Signature:	 	/s/ Michael W. Michelson
	Print Name:	 	Michael W. Michelson
	Title:	 	 

 SIGNATURE PAGE TO 
 WAIVER AND AMENDMENT AGREEMENT 

 IN WITNESS WHEREOF, the undersigned have executed
this AGREEMENT effective as of the Effective Date. 
 INVESTORS: 
  

			
	PROSPECT VENTURE PARTNERS II, L.P.
		
	By:	 	Prospect Management Co. II, LLC,
its General Partner

			
		
	Signature:	 	/s/ James Tananbaum
	Print Name:	 	James Tananbaum
	Title:	 	Managing Director
	
	PROSPECT ASSOCIATES II, L.P.

			
		
	By:	 	 Prospect Management Co. II, LLC,
 its General Partner

			
		
	Signature:	 	/s/ James Tananbaum
	Print Name:	 	James Tananbaum
	Title:	 	Managing Director

 SIGNATURE PAGE TO 
 WAIVER AND AMENDMENT AGREEMENT 

 IN WITNESS WHEREOF, the undersigned have executed
this AGREEMENT effective as of the Effective Date. 
 INVESTORS: 
  

			
	VERSANT VENTURE CAPITAL II, L.P.

			
		
	By:	 	Versant Ventures II, L.L.C.,
		 	its General Partner

			
		
	Signature:	 	/s/ Samuel D. Colella
	Print Name:	 	Samuel D. Colella
	Title:	 	Managing Director 
	
	VERSANT SIDE FUND II, L.P.

			
		
	By:	 	Versant Ventures II, L.L.C.,
		 	its General Partner

			
		
	Signature:	 	/s/ Samuel D. Colella
	Print Name:	 	Samuel D. Colella
	Title:	 	Managing Director 
	
	VERSANT AFFILIATES FUND II-A, L.P.

			
		
	By:	 	Versant Ventures II, L.L.C.,
		 	its General Partner

			
		
	Signature:	 	/s/ Samuel D. Colella
	Print Name:	 	Samuel D. Colella
	Title:	 	Managing Director 

 SIGNATURE PAGE TO 
 WAIVER AND AMENDMENT AGREEMENT 

 IN WITNESS WHEREOF, the undersigned have executed
this AGREEMENT effective as of the Effective Date. 
 INVESTORS: 
  

			
	THOMA CRESSEY FUND VII, L.P.
		
	By:	 	TC Partners VII, L.P.
	Its:	 	General Partner

			
		
	By:	 	Thoma Cressey Bravo Inc.
	Its:	 	General Partner

			
		
	Signature:	 	/s/ Bryan Cressey
	Print Name:	 	Bryan Cressey
	Title:	 	Partner
	
	THOMA CRESSEY FRIENDS FUND VII, L.P.
		
	By:	 	TC Partners VII, L.P.
	Its:	 	General Partner

			
		
	By:	 	Thoma Cressey Bravo Inc.
	Its:	 	General Partner

			
		
	Signature:	 	/s/ Bryan Cressey
	Print Name:	 	Bryan Cressey
	Title:	 	Partner

 SIGNATURE PAGE TO 
 WAIVER AND AMENDMENT AGREEMENT 

 IN WITNESS WHEREOF, the undersigned have executed
this AGREEMENT effective as of the Effective Date. 
 INVESTORS: 
  

			
	JAZZ INVESTORS, L.L.C.
		
	By:	 	Beecken Petty & Company, L.L.C.,
its Manager

			
		
	Signature:	 	/s/ Kenneth W. O’Keefe
	Print Name:	 	Kenneth W. O’Keefe
	Title:	 	Partner

 SIGNATURE PAGE TO 
 WAIVER AND AMENDMENT AGREEMENT 

 IN WITNESS WHEREOF, the undersigned have executed
this AGREEMENT effective as of the Effective Date. 
 INVESTORS: 
  

	
	
	/s/ Samuel R. Saks
	SAMUEL R. SAKS
	
	/s/ Bruce C. Cozadd
	 BRUCE C. COZADD

	
	/s/ Robert M. Myers
	ROBERT M. MYERS
	
	/s/ Janne L.T. Wissel
	JANNE L.T. WISSEL
	
	/s/ Matthew K. Fust
	MATTHEW K. FUST
	
	/s/ Carol A. Gamble
	CAROL A. GAMBLE

 SIGNATURE PAGE TO 
 WAIVER AND AMENDMENT AGREEMENT

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