Document:

Second Supplemental Indenture

 EXHIBIT 4.1 
  

 BECKMAN COULTER, INC., as Company 
 and 
 WELLS FARGO BANK, NATIONAL ASSOCIATION, as Trustee 
  

 2.50% Senior Convertible Notes
due 2036 
  

 Second Supplemental Indenture 
 Dated as of December 15, 2006 
 to 
 Senior Indenture dated as of
April 25, 2001 
  

 TABLE OF CONTENTS 
  

			
	 	  	PAGE
	 ARTICLE 1

	 CERTAIN DEFINITIONS

		
	 Section 1.01. Definitions
	  	2
	 Section 1.02. Additional Defined Terms
	  	8
	 Section 1.03. Conflicts with Base Indenture
	  	9
	
	 ARTICLE 2

	 THE NOTES

		
	 Section 2.01. Designation and Amount
	  	9
	 Section 2.02. Interest; Additional Interest; Contingent Interest
	  	9
	 Section 2.03. Restricted Global Notes
	  	11
	 Section 2.04. Legend; Additional Transfer and Exchange Requirements
	  	12
	
	 ARTICLE 3

	 COVENANTS

		
	 Section 3.01. Company May Consolidate, Etc., Only on Certain Terms
	  	14
	 Section 3.02. Resale of the Notes
	  	14
	 Section 3.03. Maintenance of Office or Agency
	  	14
	 Section 3.04. Reports by the Company
	  	14
	
	 ARTICLE 4

	 CONVERSION OF NOTES

		
	 Section 4.01. Conversion Privilege.
	  	15
	 Section 4.02. Conversion Procedure.
	  	18
	 Section 4.03. Adjustment of Conversion Rate
	  	22
	 Section 4.04. Shares To Be Fully Paid
	  	31
	 Section 4.05. Effect of Reclassification, Consolidation, Merger or Sale
	  	31
	 Section 4.06. Certain Covenants.
	  	33
	 Section 4.07. Responsibility of Trustee
	  	34
	 Section 4.08. Notice to Holders Prior to Certain Actions
	  	34
	 Section 4.09. Shareholder Rights Plans
	  	35
	
	 ARTICLE 5

	 REPURCHASE OF NOTES AT
OPTION OF HOLDERS

		
	 Section 5.01. Repurchase at Option of Holders on Specified Dates
	  	35
	 Section 5.02. Repurchase at Option of Holders Upon a Designated Event
	  	36
	 Section 5.03. Required Notes and Procedures.
	  	36

  

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	 ARTICLE 6

	 OPTIONAL REDEMPTION

		
	 Section 6.01. Right To Redeem
	  	40
	 Section 6.02. Selection of Notes To Be Redeemed
	  	40
	 Section 6.03. Notice of Redemption
	  	40
	
	 ARTICLE 7

	 EVENTS OF DEFAULT

		
	 Section 7.01. Events of Default
	  	41
	 Section 7.02. Proceedings by Holders
	  	44
	 Section 7.03. Direction of Proceedings and Waiver of Defaults by Majority of Holders
	  	45
	 Section 7.04. Notice of Defaults
	  	45
	 Section 7.05. Statement by Officers as to Default
	  	46
	
	 ARTICLE 8

	 SUPPLEMENTAL INDENTURES

		
	 Section 8.01. Supplemental Indentures without the Consent of Holders
	  	46
	 Section 8.02. Supplemental Indentures with the Consent of Holders
	  	47
	
	 ARTICLE 9

	 TAX TREATMENT

		
	 Section 9.01. Tax Treatment
	  	48
	 Section 9.02. Comparable Yield And Projected Payment Schedule.
	  	48
	
	 ARTICLE 10

	 MISCELLANEOUS

		
	 Section 10.01. Governing Law
	  	49
	 Section 10.02. Confirmation of Indenture
	  	49

  

			
	 Schedule A
	  	Make-Whole Table
	 Exhibit A
	  	Form of Note
	 Exhibit B
	  	Form of Assignment and Transfer

  

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 SECOND SUPPLEMENTAL INDENTURE, dated as of December 15, 2006 (“Supplemental
Indenture”), to the Indenture dated as of April 25, 2001 (as amended, modified or supplemented from time to time in accordance therewith, the “Base Indenture” and, as amended, modified and supplemented by this
Supplemental Indenture, the “Indenture”), by and among BECKMAN COULTER, INC. (the “Company”), and WELLS FARGO BANK, NATIONAL ASSOCIATION, as successor trustee (the “Trustee”). 
 Each party agrees as follows for the benefit of the other party and for the equal and ratable benefit of the Holders of Notes (as defined herein):

 WHEREAS, the Company has duly authorized the execution and delivery of the Base Indenture to provide for the issuance from time to time of
senior debt securities to be issued in one or more series as provided in the Base Indenture; 
 WHEREAS, Trustee was appointed as successor
trustee under the Base Indenture pursuant to that certain Instrument of Resignation, Appointment and Acceptance, dated as of December 1, 2006, among the Company, Citibank, N.A. and the Trustee; 
 WHEREAS, the Company has duly authorized the execution and delivery, and desires and has requested the Trustee to join it in the execution and delivery,
of this Supplemental Indenture in order to establish and provide for the issuance by the Company of a series of Securities designated as its 2.50% Convertible Notes due 2036 (the “Notes”), on the terms set forth herein; 

WHEREAS, Article IX of the Base Indenture provides that a supplemental indenture may be entered into by the parties for such purpose provided certain
conditions are met; 
 WHEREAS, the conditions set forth in the Base Indenture for the execution and delivery of this Supplemental Indenture
have been met; and 
 WHEREAS, all things necessary to make this Supplemental Indenture a valid agreement of the parties, in accordance with
its terms, and a valid amendment of, and supplement to, the Base Indenture with respect to the Notes have been done; 
 NOW, THEREFORE:

 ARTICLE 1 
 CERTAIN DEFINITIONS 
 Section 1.01. Definitions. The following
terms have the meanings set forth below in this Supplemental Indenture. Capitalized terms used but not defined herein have the meanings ascribed to such terms in the Base Indenture. To the extent terms defined herein differ from the Base Indenture,
the terms defined herein shall govern with respect to the Notes. 
 “Additional Interest” means all Additional Interest as
defined in the Registration Rights Agreement. 
 “Capital Stock” means, for any entity, any and all shares, interests,
rights to purchase, warrants, options, participations or other equivalents of or interests in (however designated) stock issued by that entity. 
 “close of business” means 5:00 p.m. (New York City time). 
 “Closing Price” means, with respect
to the Common Stock or any other security for which a Closing Price must be determined, on any date, the closing sale price per share of the Common Stock or unit of such other security (or, if no closing sale price is reported, the average of the
last bid and last ask prices or, if more than one in either case, the average of the average last bid and the average last ask prices) on such date as reported in composite transactions for the principal U.S. national or regional securities exchange
on which it is traded, if any. If the Common Stock or such other security is not listed for trading on a United States national or regional securities exchange on the relevant date, the Closing Price shall be the last quoted bid price per share of
Common Stock or such other security in the over-the-counter market on the relevant date, as reported by the National Quotation Bureau or similar organization. In absence of such quotation, the Closing Price shall be the average of the mid-point of
the last bid and asked prices for the Common Stock or such other security on the relevant date from each of at least three (3) nationally recognized independent investment banking firms selected from time to time by the Board of Directors of
the Company for that purpose. The Closing Price shall be determined without reference to extended or after hours trading. Any such determination by the Company will be conclusive absent manifest error. 
 “Code” means the Internal Revenue Code of 1983, as amended. 
 “Common Stock” means, subject to Section 4.05, shares of common stock of the Company, par value $0.10 per share, at the date of
this Indenture or shares of any class or classes resulting from any reclassification or reclassifications thereof and that have no preference in respect of dividends or of amounts payable in the event of any voluntary or involuntary liquidation,
dissolution or winding up of the Company and that are not subject to redemption by the Company; provided that if at any time there shall be more than one such 
  

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 resulting class, the shares of each such class then so issuable shall be substantially in the proportion which the total
number of shares of such class resulting from all such reclassifications bears to the total number of shares of all such classes resulting from all such reclassifications. 
 “Company” means Beckman Coulter, Inc., a Delaware corporation, and subject to the provisions of Article VIII of the Base Indenture,
shall include its successors and assigns and, to the extent the obligations hereunder shall be of more than one entity pursuant to Section 4.05, shall include each of such entities. 
 “Conversion Price” means as of any date $1,000 divided by the Conversion Rate as of such date. 
 “Corporate Trust Office” or other similar term means the principal corporate trust office of the Trustee at which at any particular time
its corporate trust business shall be principally administered, which office is, at the date as of which this Supplemental Indenture is dated, located at 707 Wilshire Blvd, 17th Floor, Corporate Trust Dept., Los Angeles, CA 90017. 
 “Custodian” means Wells Fargo Bank, National Association, as custodian for The Depository Trust Company, with respect to the Notes in
global form, or any successor entity thereto. 
 “Daily Conversion Value” means, for each of the twenty
(20) consecutive Trading Days during the Observation Period, one-twentieth (1/20) of the product of (1) the applicable Conversion Rate and (2) the Daily VWAP of the Common Stock (or the Reference Property pursuant to
Section 4.05) on such day, as determined by the Company. Any such determination by the Company shall be conclusive absent manifest error. 
 “Daily Settlement Amount,” for each of the twenty (20) Trading Days during the Observation Period, shall consist of: 
  

	 	(1)	cash equal to the lesser of $50 and the Daily Conversion Value relating to such day; and 

  

	 	(2)	to the extent such Daily Conversion Value exceeds $50, a number of shares of Common Stock equal to (A) the difference between such Daily Conversion Value and $50, divided by
(B) the Daily VWAP of the Common Stock for such day. 

 “Daily VWAP” of the Common Stock means, for each
of the twenty (20) consecutive Trading Days during the Observation Period, the per share volume-weighted average price as displayed under the heading “Bloomberg VWAP” on Bloomberg page BEC <equity> AQR (or any successor page) in
respect of the period from 9:30 a.m. to 4:00 p.m. (New York City time) on such Trading Day 
  

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 (or if such volume-weighted average price is unavailable, the market value of one share of Common Stock on such Trading
Day as the Board of Directors determines in good faith using a volume-weighted method). Daily VWAP of the Reference Property shall have a comparable meaning, mutatis mutandis. 
 “Default” means any event that is, or after notice or passage of time, or both, would be, an Event of Default. 
 “Designated Event” means the occurrence of either a Fundamental Change or a Termination of Trading. 
 “Dividend Threshold Amount” means $0.15 per fiscal quarter, appropriately adjusted from time to time to take into account the
occurrence, on or before the date of determination, of any event that would require an adjustment to the Conversion Rate, as set forth in Section 4.03, and to account for any change in the frequency or timing of payment of the Company’s
regular dividend. 
 “Event of Default” means, with respect to the Notes, any event specified in Section 7.01,
continued for the period of time, if any, and after the giving of notice, if any, therein designated. 
 “Ex-Dividend Date”
means, (1) with respect to Section 4.01(b), the first date upon which a sale of the Common Stock does not automatically transfer the right to receive the relevant dividend from the seller of the Common Stock to its buyer, and (2) in
all other cases, with respect to any issuance or distribution on the Common Stock or any other equity security, the first date on which the shares of Common Stock or such other equity security trade on the applicable exchange or in the applicable
market, regular way, without the right to receive such issuance or distribution. 
 “Fair Market Value” means the amount
which a willing buyer would pay a willing seller in an arm’s length transaction (as determined in good faith by the Board of Directors, whose good faith determination shall be conclusive). 
 “Fundamental Change” means any transaction or event (whether by means of an exchange offer, liquidation, tender offer, consolidation,
merger, combination, reclassification, recapitalization or otherwise) in connection with which more than 50% of the Common Stock is exchanged for, converted into, acquired for or constitutes solely the right to receive, consideration which is not at
least 90% shares of common stock, or depositary receipts representing such shares, that are: 
  

	 	(1)	listed on, or immediately after the transaction or event will be listed on, a United States national securities exchange; or 

  

	 	(2)	approved, or immediately after the transaction or event will be approved, for quotation on a United States system of automated 

  

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 dissemination of quotations of securities prices similar to the NASDAQ National Market prior to its
designation as a national securities exchange. 
 “Global Notes” means Notes that are Global Securities (as defined in the
Base Indenture). 
 “Market Disruption Event” means the occurrence or existence for more than one-half hour period in the
aggregate on any scheduled Trading Day for the Common Stock of any suspension or limitation imposed on trading (by reason of movements in price exceeding limits permitted by the stock exchange or otherwise) in the Common Stock or in any options,
contracts or future contracts relating to the Common Stock, any such suspension or limitation occurs or exists at any time prior to 1:00 p.m. (New York City time) on such day. 
 “Observation Period” with respect to any Note means the twenty (20) consecutive Trading Day period beginning on and including the
second Trading Day after the related Conversion Date in respect of such Note. 
 “Outstanding” or
“outstanding” when used with respect to the Notes, means, as of the date of determination, all Notes theretofore authenticated and delivered under this Indenture, except: 
  

	 	(1)	Notes theretofore canceled by the Trustee or delivered to the Trustee for cancellation; 

  

	 	(2)	Notes for whose payment or redemption the necessary amount of money or money’s worth has been theretofore deposited with the Trustee or any Paying Agent (other than the
Company) in trust or set aside and segregated in trust by the Company (if the Company shall act as its own Paying Agent) for the Holders of such Securities; provided that, if such Notes are to be redeemed, notice of such redemption has been duly
given pursuant to this Indenture or provision therefor satisfactory to the Trustee has been made; 

  

	 	(3)	Notes as to which Defeasance has been effected pursuant to Section 1302 of the Base Indenture; 

  

	 	(4)	Notes which have been paid pursuant to Section 306 of the Base Indenture or in exchange for or in lieu of which other Notes have been authenticated and delivered pursuant to
this Indenture, other than any such Notes in respect of which there shall have been presented to the Trustee proof satisfactory to it that such Notes are held by a bona fide purchaser in whose hands such Notes are valid obligations of the Company;
and 

  

	 	(5)	Notes converted pursuant to Article 4 hereof; 

  

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 provided, however, that in determining whether the Holders of the requisite principal amount of the
Outstanding Notes have given, made or taken any request, demand, authorization, direction, notice, consent, waiver or other action hereunder as of any date, Notes owned by the Company or any other obligor upon the Notes or any Affiliate of the
Company or of such other obligor, whether of record or beneficially, shall be disregarded and deemed not to be Outstanding, except that, in determining whether the Trustee shall be protected in relying upon any such request, demand, authorization,
direction, notice, consent, waiver or other action, only Notes which a Responsible Officer of the Trustee actually knows to be so owned shall be so disregarded. Notes so owned which have been pledged in good faith may be regarded as Outstanding if
the pledgee establishes to the satisfaction of the Trustee the pledgee’s right so to act with respect to such Notes and that the pledgee is not the Company or any other obligor upon the Notes or any Affiliate of the Company or of such other
obligor. 
 “Person” means an individual, a corporation, a limited liability company, an association, a partnership, a joint
venture, a joint stock company, a trust, an unincorporated organization or a government or an agency or a political subdivision thereof, including any syndicate or group that would be deemed to be a “person” under Section 13(d)(3) of
the Exchange Act. 
 “Portal Market” means The Portal Market operated by the National Association of Securities Dealers,
Inc. or any successor thereto. 
 “Redemption Date” means, when used with respect to any Note to be redeemed, the date fixed
for redemption pursuant to the Indenture. 
 “Registration Date” means, when used with respect to any Note to be redeemed,
the date fixed for redemption pursuant to the Indenture. 
 “Registration Rights Agreement” means that certain Registration
Rights Agreement, dated as of December 15, 2006, among the Company and the Initial Purchasers. 
 “Restricted Global
Note” means a Global Note that is a Restricted Security. 
 “Restricted Security” means a Security required to bear
the Legend. 
 “Rights Plan” means that certain Stockholder Protection Rights Agreement dated February 4, 1999 between
the Company and First Chicago Trust Company of New York, as rights agent, as amended or replaced from time to time. 
 “Rule
144” means Rule 144 under the Securities Act or any successor to such Rule. 
  

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 “Rule 144A” means Rule 144A under the Securities Act or any successor to such Rule.

 “Significant Subsidiary” means such Subsidiary of the Company as meets the definition of “significant
subsidiary” in Rule 1-02 of Regulation S-X promulgated by the Commission as in effect on the original date of issuance of the Notes. 
 “Stock Price” means the price paid per share of Common Stock in connection with a Fundamental Change pursuant to which the Conversion Rate shall be increased as set forth in Section 4.01(d) hereof, which shall be equal
to (1) if holders of Common Stock receive only cash in such Fundamental Change, the cash amount paid per share of Common Stock and (2) in all other cases, the average of the Closing Prices of the Common Stock over the five
(5) consecutive Trading Day period ending on the Trading Day preceding the Effective Date of the Fundamental Change. 
 “Subsidiary” of the Company means (1) a corporation a majority of whose Capital Stock with voting power, under ordinary circumstances, to elect directors is at the time, directly or indirectly, owned by the Company, by
the Company and one or more Subsidiaries of the Company or by one or more Subsidiaries of the Company or (2) any other Person (other than a corporation) in which the Company, one or more Subsidiaries of the Company or the Company and one or
more Subsidiaries of the Company, directly or indirectly, at the date of determination thereof, has greater than a 50% ownership interest. 
 “Termination of Trading” means the occurrence of the Common Stock not being listed for trading on a U.S. national securities exchange. 
 “Trading Day” means a day during which (1) trading in the Common Stock generally occurs, (2) there is no Market Disruption Event and (3) a Closing Price for the Common Stock (other than
a Closing Price referred to in the next to last sentence of such definition) is available for such day; provided that if the Common Stock is not admitted for trading or quotation on or by any exchange, bureau or other organization referred to in the
definition of Closing Price (excluding the next to last sentence of that definition), Trading Date shall mean any Business Day. 
 “Trading Price” with respect to the Notes, on any date of determination, means the average of the secondary market bid quotations obtained by the Trustee for $2.0 million principal amount of Notes at approximately 3:30
p.m., New York City time, on such determination date from three (3) independent nationally recognized securities dealers selected by the Company (which may include any or all of the Initial Purchasers); provided that if three
(3) such bids cannot reasonably be obtained by the Trustee, but two (2) such bids are obtained, then the average of the two (2) bids shall be used, and if only one such bid can reasonably be obtained by the Trustee, that one bid shall
be used. If the Trustee cannot reasonably obtain 
  

 7 

 at least one bid for $2.0 million principal amount of Notes from a nationally recognized securities dealer, then the
Trading Price per $1,000 principal amount of Notes will be deemed to be equal to the product of the Closing Price of the Common Stock (as provided to the Trustee by the Company) and the Conversion Rate; provided, however, that for
purposes of determining the “Trading Price” as used in Section 2.02(c) only, if the Trustee cannot reasonably obtain at least one bid for $2.0 million principal amount of the Notes from a nationally recognized securities dealer, then
the Trading Price of per $1,000 principal amount of Notes will be deemed to equal the product of (1) the Conversion Rate on such determination date and (2) the average Closing Sale Price of a share of Common Stock over the five
(5) Trading-Day period ending on such determination date. Any such determination by the Trustee will be conclusive absent manifest error. 
 Section 1.02. Additional Defined Terms. Each of the following terms is defined in the Section set forth opposite such term: 
  

			
	 Term
	  	Section
	 Additional Shares
	  	4.01(e)
	 Adjustment Determination Date
	  	4.03(j)
	 Adjustment Event
	  	4.03(j)
	 Base Indenture
	  	Preamble
	 Contingent Interest
	  	2.02(c)
	 Company Notice
	  	5.03(b)
	 Conversion Agent
	  	3.03
	 Conversion Date
	  	4.02(c)
	 Conversion Obligation
	  	4.01(a)
	 Conversion Rate
	  	4.01(a)
	 Distributed Property
	  	4.03(c)
	 Effective Date
	  	4.01(e)(ii)
	 Expiration Time
	  	5.03(b)(viii)
	 Designated Event Repurchase Date
	  	5.02
	 Designated Event Repurchase Price
	  	5.02
	 Indenture
	  	Preamble
	 Initial Purchasers
	  	2.03
	 Interest Payment Date
	  	2.02(a)
	 Legend
	  	2.04(a)
	 Measurement Period
	  	4.01(a)(i)
	 Merger Event
	  	4.05
	 Notes
	  	Recitals
	 Notice of Conversion
	  	4.02(c)
	 Paying Agent
	  	3.03
	 Period
	  	7.01(k)
	 Purchase Agreement
	  	2.03
	 Purchase Price
	  	5.01
	 QIBs or QIB
	  	2.03
	 Record Date
	  	4.03(f)

  

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	 Term
	  	Section
	 Redemption Price
	  	6.01
	 Reference Property
	  	4.05(b)
	 Regular Record Date
	  	2.02(a)
	 Reporting Interest
	  	7.01(k)
	 Repurchase Notice
	  	5.03(a)(i)
	 Specified Purchase Date
	  	5.01
	 Spin-Off
	  	4.03(c)
	 Supplemental Indenture
	  	Preamble
	 Trigger Event
	  	4.03(c)
	 Trustee
	  	Preamble

 Section 1.03. Conflicts with Base Indenture. In the event that any provision of this
Supplemental Indenture limits, qualifies or conflicts with a provision of the Base Indenture, the provision of this Supplemental Indenture shall control. 
 ARTICLE 2 
 THE NOTES 
 Section 2.01. Designation and Amount. The changes, modifications and supplements to the Base Indenture effected by this Supplemental
Indenture shall be applicable only with respect to, and govern the terms of, the Notes and shall not apply to any other series of Securities that may be issued under the Base Indenture unless a supplemental indenture with respect to such other
series of Securities specifically incorporates such changes, modifications and supplements. The Notes shall be initially limited to an aggregate principal amount of $600,000,000. Pursuant to this Supplemental Indenture, there is hereby created and
designated a series of Securities under the Indenture entitled “2.50% Senior Convertible Notes due 2036”. The Notes shall be in the form of Exhibit A hereto. 
 The Stated Maturity of the Notes will be December 15, 2036 unless earlier converted, redeemed or repurchased. The Notes shall be payable and may be presented for payment, purchase, redemption, conversion,
registration of transfer and exchange, without service charge, at the office of the Company maintained for such purpose in Minneapolis, Minnesota, which shall initially be the office or agency of the Trustee. 
 Section 2.02. Interest; Additional Interest; Contingent Interest. (a) The Company covenants and agrees that it will cause to be paid the
principal of, and accrued and unpaid interest on, each of the Notes and if applicable, payment of the Conversion Obligation and Additional Shares, at the places, at the respective times and in the manner provided herein and in the Notes. Each
installment of accrued and unpaid interest on the Notes due on any Interest Payment Date (defined below) may be paid by mailing checks for the amount payable to or upon 
  

 9 

 the written order of the Holders entitled thereto as they shall appear on the registry books of the Company, provided
that, with respect to any Holder with an aggregate principal amount in excess of $1,000,000, at the application of such Holder in writing to the Trustee or the Paying Agent not later than the relevant record date, accrued and unpaid interest on such
Holder’s Notes shall be paid by wire transfer in immediately available funds to such Holder’s account in the United States supplied by such Holder from time to time to the Trustee and Paying Agent (if different from Trustee); provided
further that payment of accrued and unpaid interest made to the Depositary shall be paid by wire transfer in immediately available funds in accordance with such wire transfer instructions and other procedures provided by the Depositary from time to
time. 
 Interest shall be computed on the basis of a 360 day year composed of twelve 30 day months. Interest will accrue from the date of
initial issuance, or from the most recent Interest Payment Date to which interest has been paid and be payable semiannually in arrears on each June 15 and December 15 (each, an “Interest Payment Date”), commencing on
June 15, 2007, to Holders of record on the preceding June 1 and December 1 (each, a “Regular Record Date”). 
 (b) If required by the Registration Rights Agreement, each Note shall pay Additional Interest in the manner and to the Persons set forth in the Registration Rights Agreement. If Additional Interest is payable by the Company pursuant to the
Registration Rights Agreement, the Company shall deliver to the Trustee an Officers’ Certificate to that effect stating (i) the amount of such Additional Interest that is payable and (ii) the date on which such interest is payable.
Unless and until a Responsible Officer of the Trustee receives at the Corporate Trust Office such a certificate, the Trustee may assume without inquiry that no such Additional Interest is payable. If the Company has paid Additional Interest directly
to the Persons entitled to them, the Company shall deliver to the Trustee an Officers’ Certificate setting forth the particulars of such payment. 
 (c) (i) Beginning with the six-month interest period commencing December 15, 2012, the Company will pay contingent interest (“Contingent Interest”) during any six-month interest period if the
Trading Price of the Notes for each of the five (5) Trading Days ending on the Trading Day immediately preceding the first day of the applicable six-month interest period equals or exceeds 120% of the principal amount of the Notes. During any
six-month interest period when Contingent Interest is payable, the Contingent Interest payable on each $1,000 principal amount of Notes shall equal the greater of (1) 0.2795% and (2) 0.25% of the average Trading Price of $1,000 principal
amount of Notes during the five (5) Trading Days immediately preceding the first day of the applicable six-month interest period used to determine whether Contingent Interest must be paid. The Trustee’s sole responsibility pursuant to
Section 2.02(c)(i) hereof shall be to obtain the Trading Price of the Notes for each of the five (5) Trading Days immediately preceding the first day of the applicable six-month interest period and to provide such information to the
Company. The Company shall determine whether Holders are entitled to receive Contingent 
  

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 Interest, and if so, provide notice pursuant to Section 2.02(c)(iii). Notwithstanding any term contained in this
Indenture or any other document to the contrary, the Trustee shall have no responsibilities, duties or obligations for or with respect to (x) determining whether the Company must pay Contingent Interest or (y) determining the amount of
Contingent Interest, if any, payable by the Company. 
 (ii) Contingent Interest for any six-month interest period shall be
paid on the applicable interest payment date to the Person in whose name any Note (or its Predecessor Note) is registered on the Security Register at the corresponding Regular Record Date. Contingent Interest due under this Section 2.02 shall
be treated for all purposes of this Indenture like any other interest accruing on the Notes. 
 (iii) On or before the first
Business Day of a six-month interest period during which contingent interest will be paid, the Company shall disseminate a press release through Dow Jones & Company, Inc. or Bloomberg Business News stating that contingent interest will be
paid on the Notes and identifying the six-month interest period. 
 (d) Whenever in this Supplemental Indenture there is mentioned, in any
context, the payment of interest on, or in respect of, any Note, such mention shall be deemed to include mention of the payment of “Additional Interest” provided for in the Registration Rights Agreement and Reporting Interest and
Contingent Interest provided for herein to the extent that, in such context, Additional Interest, Reporting Interest or Contingent Interest is, was or would be payable in respect thereof pursuant to the provisions thereof or hereof, as the case may
be, and express mention of the payment of Additional Interest, Reporting Interest or Contingent Interest in any provisions hereof shall not be construed as excluding Additional Interest, Reporting Interest or Contingent Interest in those provisions
hereof where such express mention is not made. 
 Section 2.03. Restricted Global Notes. The Notes are being sold by the Company
pursuant to a Purchase Agreement dated December 11, 2006 (the “Purchase Agreement”) between the Company and the several purchasers named in Schedule I thereto (collectively, the “Initial Purchasers”), in
transactions exempt from, or not subject to, the registration requirements of the Securities Act. All of the Notes are initially being offered and sold to qualified institutional buyers as defined in Rule 144A (collectively, “QIBs”
or individually, each a “QIB”) in reliance on Rule 144A under the Securities Act and shall be issued initially in the form of one or more Restricted Global Notes, which shall be deposited on behalf of the purchasers of the
securities represented thereby with the Trustee, at its Corporate Trust Office, as Custodian, and registered in the name of DTC’s nominee, Cede & Co. (or any successor thereto), for the accounts of participants in the Depositary, duly
executed by the Company and authenticated by the Trustee as provided in the Base Indenture. 
  

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 Section 2.04. Legend; Additional Transfer and Exchange Requirements. (a) If Notes are
issued upon the transfer, exchange or replacement of Notes subject to restrictions on transfer and bearing the legends set forth in Exhibit A hereto (collectively, the “Legend”), or if a request is made to remove the Legend on a
Note, the Notes so issued shall bear the Legend, or the Legend shall not be removed, as the case may be, unless there is delivered to the Company and the Security Registrar such satisfactory evidence, which shall include an Opinion of Counsel, as
may be reasonably required by the Company and the Security Registrar, that neither the Legend nor the restrictions on transfer set forth therein are required to ensure that transfers thereof comply with the provisions of Rule 144A or Rule 144 under
the Securities Act or that such Notes are not “restricted” within the meaning of Rule 144 under the Securities Act; provided that no such evidence need be supplied in connection with the sale of such Note pursuant to a registration
statement that is effective at the time of such sale. Upon (i) provision of such satisfactory evidence if requested, or (ii) notification by the Company to the Trustee and Security Registrar of the sale of such Note pursuant to a
registration statement that is effective at the time of such sale, the Trustee, upon Company Order as provided in Section 303 of the Base Indenture, shall authenticate and deliver a Note that does not bear the Legend. If the Legend is removed
from the face of a Note and the Note is subsequently held by an Affiliate of the Company, the Legend shall be reinstated. 
 (b) Subject to
Section 2.04(c), every Note shall be subject to the restrictions on transfer provided in the Legend. Whenever any Restricted Security other than a Restricted Global Note is presented or surrendered for registration of transfer or in exchange
for a Note registered in a name other than that of the Holder, such Note must be accompanied by a certificate in substantially the form set forth in Exhibit B, dated the date of such surrender and signed by the Holder of such Note, as to compliance
with such restrictions on transfer. The Security Registrar shall not be required to accept for such registration of transfer or exchange any Note not so accompanied by a properly completed certificate. 
 (c) The restrictions imposed by the Legend upon the transferability of any Note shall cease and terminate when such Note has been sold pursuant to an
effective registration statement under the Securities Act or transferred in compliance with Rule 144 under the Securities Act (or any successor provision thereto) or, if earlier, upon the expiration of the holding period applicable to sales thereof
under Rule 144(k) under the Securities Act (or any successor provision). Any Note as to which such restrictions on transfer shall have expired in accordance with their terms or shall have terminated may, upon a surrender of such Note for exchange to
the Security Registrar in accordance with the provisions of Section 305 of the Base Indenture and this Section 2.04 (accompanied, if such restrictions on transfer have terminated by reason of a transfer in compliance with Rule 144 or any
successor provision, by an Opinion of Counsel reasonably acceptable to the Company and the Security Registrar and addressed to the Company and the Security Registrar, to the effect that the 
  

 12 

 transfer of such Note has been made in compliance with Rule 144 or such successor provision), be exchanged for a new
Note, of like tenor and aggregate principal amount, which shall not bear the Legend. The Company shall inform the Trustee of the effective date of any registration statement registering the offer and sale of the Notes under the Securities Act. The
Trustee or the Security Registrar shall not be liable for any action taken or omitted to be taken by it in good faith in accordance with the aforementioned Opinion of Counsel. 
 As used in Section 2.04(b) and Section 2.04(c), the term “transfer” encompasses any sale, pledge, transfer, hypothecation or other
disposition of any Note. 
 (d) Until the expiration of the holding period applicable to sales thereof under Rule 144(k) under the Securities
Act (or any successor provision thereto), any certificate representing any Note shall bear a legend in substantially the form set forth in Exhibit A hereto, unless such Note has been sold pursuant to a registration statement that has been declared
effective under the Securities Act (and which continues to be effective at the time of such transfer) or transferred in compliance with Rule 144 under the Securities Act (or any successor provision thereto), or unless otherwise agreed by the Company
in writing with written notice thereof to the transfer agent. 
 Any such Common Stock as to which such restrictions on transfer shall have
expired in accordance with their terms or as to which the conditions for removal of the legend set forth therein have been satisfied may, upon surrender of the certificates representing such shares of Common Stock for exchange in accordance with the
procedures of the transfer agent for the Common Stock, be exchanged for a new certificate or certificates for a like number of shares of Common Stock, which shall not bear the restrictive legend required by this section. 
 (e) Any Global Note may be endorsed with or have incorporated in the text thereof such other legends or recitals or changes not inconsistent with the
provisions of this Indenture as may be required by the Custodian, the Depositary or by the National Association of Securities Dealers, Inc. in order for the Notes to be tradable on The Portal Market or as may be required for the Notes to be tradable
on any other market developed for trading of securities pursuant to Rule 144A or required to comply with any applicable law or any regulation thereunder or with the rules and regulations of any securities exchange or automated quotation system upon
which the Notes may be listed or traded or designated for issuance or to conform with any usage with respect thereto, or to indicate any special limitations or restrictions to which any particular Notes are subject. 
  

 13 

 ARTICLE 3 
 COVENANTS 
 Section 3.01. Company May Consolidate, Etc., Only on Certain Terms.
Section 801 of the Base Indenture is hereby amended with respect to the Notes by replacing the portion of the first paragraph immediately preceding clause (1) thereof with the following: 
 “The Company shall not consolidate with or merge into any other Person or convey, transfer or lease its properties and assets substantially as an
entirety to any Person (other than conveyances, transfers or leases to a wholly owned Subsidiary of the Company) unless:” 
 Section 3.02. Resale of the Notes. During the period of two (2) years after the last original issuance of the Notes the Company shall not, and shall not permit any of its Affiliates to, resell any of the Notes that
constitute “restricted securities” under Rule 144 that have been reacquired by any of them. 
 Section 3.03. Maintenance of
Office or Agency. In accordance with Section 1002 of the Base Indenture, the Company will maintain an office or agency where the Notes may be surrendered for registration of transfer or exchange or for presentation for payment, redemptions
or repurchase (“Paying Agent”) or for conversion (“Conversion Agent”) and where notices and demands to or upon the Company in respect of the Notes and this Indenture may be served. The Company will give prompt
written notice to the Trustee of the location, and any change in the location, of such office or agency not designated or appointed by the Trustee. If at any time the Company shall fail to maintain any such required office or agency or shall fail to
furnish the Trustee with the address thereof, such presentations, surrenders, notices and demands may be made or served at the Corporate Trust Office or the office or agency of the Trustee in Los Angeles, California. 
 Section 3.04. Reports by the Company. Section 704 of the Base Indenture is hereby amended with respect to the Notes by replacing the
first sentence thereof with the following: 
 “The Company shall file with the Trustee and the Commission, and transmit to Holders, such
information, documents and other reports, and such summaries thereof, as may be required pursuant to the Trust Indenture Act, provided that any such information, documents or reports required to be filed by the Company with the Commission pursuant
to Section 13 or 15(d) of the Exchange Act shall be filed with the Trustee within 15 days after the same is filed by the Company with the Commission.” 
  

 14 

 ARTICLE 4 
 CONVERSION OF NOTES 
 Section 4.01. Conversion
Privilege.  
 (a) Subject to the conditions described in clauses (i), (ii), (iii) and (iv) below, and upon compliance with the
provisions of this Article 4, a Holder shall have the right, at such Holder’s option, to convert all or any portion (if the portion to be converted is $1,000 principal amount or a multiple thereof) of such Note at any time prior to the close of
business on the scheduled Trading Day immediately preceding December 15, 2013 at a rate (the “Conversion Rate”) of 13.4748 shares of Common Stock (subject to adjustment by the Company as provided in
Section 4.03) per $1,000 principal amount Note (the “Conversion Obligation”) under the circumstances and during the periods set forth below. On and after December 15, 2013, regardless of the conditions described in
clauses (i), (ii), (iii) and (iv) below, and upon compliance with the provisions of this Article 4, a Holder shall have the right, at such Holder’s option, to convert all or any portion (if the portion to be converted is $1,000
principal amount or a multiple thereof) of such Note at any time prior to the close of business on the scheduled Trading Day immediately preceding the Stated Maturity. 
 (i) The Notes shall be convertible prior to December 15, 2013, during the five (5) Business Day period immediately after any ten
(10) consecutive Trading Day period (the “Measurement Period”) in which the Trading Price per $1,000 principal amount of Notes for each day of such Measurement Period was less than 98% of the product of the Closing Price of the
Common Stock on such date and the Conversion Rate on such date, all as determined by the Trustee. The Trustee shall have no obligation to determine the Trading Price of the Notes unless requested by the Company to do so in writing, and the Company
shall have no obligation to make such request unless a Holder provides the Company with reasonable evidence that the Trading Price of the Notes would be less than 98% of the product of (a) the then-applicable Conversion Rate of the Notes and
(b) the Closing Price at such time, at which time the Company shall instruct the Trustee to determine the Trading Price of the Notes beginning on the next Trading Day and on each successive Trading Day until the Trading Price per Note is
greater than or equal to 98% of the product of (1) the then-applicable Conversion Rate of the Notes and (2) the Closing Price on such date. If the Trading Price condition set forth above has been met, the Company shall so notify the
Holders. If, at any time after the Trading Price condition set forth above has been met, the Trading Price per $1,000 principal amount of Notes is greater than 98% of the product of (x) the then-applicable Conversion Rate of the Notes and
(y) the Closing Price on such date, the Company shall so notify the Holders. 
 (ii) The Notes shall be convertible prior
to December 15, 2013, during any calendar quarter after the calendar quarter ending December 31, 
  

 15 

 2006, if the Closing Price of the Common Stock for twenty (20) or more consecutive Trading Days in a
period of thirty (30) consecutive Trading Days ending on the last Trading Day of the immediately preceding calendar quarter exceeds 130% of the applicable Conversion Price in effect on the last Trading Day of the immediately preceding calendar
quarter. 
 (iii) The Notes shall be convertible prior to December 15, 2013 as provided in Section 4.01(b),
Section 4.01(c) and Section 4.01(d). 
 (iv) The Notes shall be convertible prior to December 15, 2013, at any
time prior to the close of business on the Business Day immediately preceding the Redemption Date, if the Company has called a Note for redemption pursuant to Article 6 hereof. 
 (b) If the Company elects to: 
 (i) distribute to all or substantially all holders of Common Stock rights entitling them to purchase, for a period expiring within sixty (60) days after the record date for such distribution, Common Stock at a price less than the
average of the Closing Prices of the Common Stock for the five (5) consecutive Trading Days immediately preceding the first public announcement of such distribution; or 
 (ii) distribute to all or substantially all holders of Common Stock, cash, debt securities or other assets of the Company excluding
dividends or distributions pursuant to Section 4.03(d) and cash dividends not in excess of the Dividend Threshold Amount per share of Common Stock per fiscal quarter, which distribution has a per share value (as determined by the Board of
Directors) exceeding 15% of the average of Closing Prices of the Common Stock for the five (5) consecutive Trading Days immediately preceding the first public announcement of such distribution, 
 then, in either case, Holders may surrender the Notes for conversion at any time on and after the date that the Company provides notice to Holders referred to in the
next sentence until the earlier of the close of business on the Business Day immediately preceding the Ex-Dividend Date for such distribution or the date the Company announces that such distribution will not take place. The Company shall notify
Holders of any distribution referred to in either clause (i) or clause (ii) above and of the resulting conversion right no later than the twenty-fifth (25th) scheduled Trading Day prior to the Ex-Dividend Date for such distribution. Holders may not exercise this right if such Holder participates in the
distribution without conversion. 
 (c) If the Company consolidates with or merges with or into another Person or is a party to a binding
share exchange or conveys, transfers, sells, leases 
  

 16 

 or otherwise disposes of all or substantially all of its properties and assets in each case pursuant to which the Common
Stock would be converted into cash, securities and/or other property, then the Holders shall have the right to convert Notes at any time beginning fifteen (15) scheduled Trading Days prior to the date announced by the Company as the anticipated
effective date of the transaction and ending on the fifteenth (15th) scheduled Trading Day following the
effective date of such transaction; provided such transaction does not otherwise constitute a Designated Event to which the provisions of Section 4.01(d) shall apply. The Company will notify Holders at least twenty-five
(25) scheduled Trading Days prior to the anticipated effective date of such transaction. The Board of Directors shall determine the anticipated effective date of the transaction, and such determination shall be conclusive and binding on the
Holders. 
 (d) If the Company is a party to any transaction or event that constitutes a Fundamental Change, a Holder may surrender Notes for
conversion at any time on or after the thirtieth (30th) scheduled Trading Day prior to the anticipated
effective date of such transaction or event until the related Designated Event Repurchase Date and, upon such surrender, the Holder shall be entitled to the increase in the Conversion Rate, if any, specified in Section 4.01(e). The Company
shall give notice in writing to all record Holders and the Trustee of the Designated Event no later than thirty (30) scheduled Trading Days prior to the anticipated effective date of the Fundamental Change. 
 (e) (i) If a Holder elects to convert Notes in connection with a Fundamental Change that occurs prior to December 15, 2013, the Conversion Rate
applicable to each $1,000 principal amount of Notes so converted shall be increased by an additional number of shares of Common Stock (the “Additional Shares”) as described below; provided, however, that no increase
will be made in the case of Fundamental Change if at least 90% of the consideration paid for the Common Stock (excluding cash payments for fractional shares and cash payments made pursuant to dissenters’ appraisal rights) in such Fundamental
Change transaction consists of shares of capital stock listed on a U.S. national securities exchange or approved for quotation on a Unites States system of automated dissemination of quotations of securities prices similar to the NASDAQ National
Market prior to its designation as a U.S. national securities exchange or another established automated over-the-counter trading market in the United States (or that will be so listed or quoted immediately following the transaction) and as a result
of such transaction or transactions the Notes become convertible solely into such common stock. Settlement of Notes tendered for conversion to which Additional Shares shall be added to the Conversion Rate as provided in this subsection shall be
settled pursuant to Section 4.02(b) below. For purposes of this Section 4.01(e), a conversion shall be deemed to be “in connection” with a Fundamental Change to the extent that such conversion is effected during the time period
specified in Section 4.01(d) (regardless of whether the provisions of clause (a)(i), (a)(ii), (b) or (c) of this Section 4.01 shall apply to such conversion). 
  

 17 

 (ii) The number of Additional Shares by which the Conversion Rate will be increased shall
be determined by reference to the table attached as Schedule A hereto, based on the date on which the Fundamental Change occurs or becomes effective (the “Effective Date”), and the Stock Price; provided that if the actual
Stock Price is between two Stock Price amounts in the table or the Effective Date is between two Effective Dates in the table, the number of Additional Shares shall be determined by a straight-line interpolation between the number of Additional
Shares set forth for the next higher and next lower Stock Price amounts and the two nearest Effective Dates, as applicable, based on a 365-day year; provided further that if (1) the Stock Price is greater than $200.00 per share of Common
Stock (subject to adjustment in the same manner as set forth in Section 4.03), no Additional Shares will be added to the Conversion Rate, and (2) the Stock Price is less than $59.37 per share (subject to adjustment in the same manner as
set forth in Section 4.03), no Additional Shares will be added to the Conversion Rate. Notwithstanding the foregoing, in no event will the total number of shares of Common Stock issuable upon conversion exceed 16.8435 per $1,000 principal
amount of Notes (subject to adjustment in the same manner as set forth in Section 4.03). 
 (iii) The Stock Prices set
forth in the first row of the table in Schedule A hereto shall be adjusted by the Company as of any date on which the Conversion Rate of the Notes is adjusted. The adjusted Stock Prices shall equal the Stock Prices applicable immediately prior to
such adjustment, multiplied by a fraction, the numerator of which is the Conversion Rate in effect immediately prior to the adjustment giving rise to the Stock Price adjustment and the denominator of which is the Conversion Rate as so adjusted. The
number of Additional Shares within the table shall be adjusted in the same manner as the Conversion Rate as set forth in Section 4.03 (other than by operation of an adjustment to the Conversion Rate by adding Additional Shares). 
 Section 4.02. Conversion Procedure.  
 (a) Subject to Section 4.02(b), the Company will satisfy the Conversion Obligation with respect to each $1,000 principal amount of Notes tendered for conversion in cash and shares of fully paid Common Stock, if applicable, by
delivering, on the third Trading Day immediately following the last day of the related Observation Period, cash and shares of Common Stock, if any, equal to the sum of the Daily Settlement Amounts for each of the twenty (20) Trading Days during
the related Observation Period; provided that the Company will deliver cash in lieu of fractional shares of Common Stock as set forth pursuant to clause (k) below. The Daily Settlement Amounts shall be determined by the Company promptly
following the last day of the Observation Period. 
  

 18 

 (b) Notwithstanding Section 4.02(a), the Company shall satisfy the Conversion Obligation with
respect to each $1,000 principal amount of Notes tendered for conversion to which Additional Shares shall be added to the Conversion Rate as set forth in Section 4.01(e) pursuant to this clause (b). 
 (i) If the last day of the applicable Observation Period related to Notes surrendered for conversion is prior to the third Trading Day
preceding the Effective Date of the Fundamental Change, the Company will satisfy the related Conversion Obligation with respect to each $1,000 principal amount of Notes tendered for conversion as described in Section 4.02(b) by delivering the
cash and shares of Common Stock (based on the Conversion Rate, but without regard to the number of Additional Shares to be added to the Conversion Rate pursuant to Section 4.01(e)) on the third Trading Day immediately following the last day of
the applicable Observation Period. As soon as practicable following the Effective Date of the Fundamental Change, the Company will deliver the increase in such amount of cash and Reference Property in lieu of shares of Common Stock, if any, as if
the Conversion Rate had been increased by such number of Additional Shares during the related Observation Period (and based upon the related Daily VWAP prices during such Observation Period). If such increased amount of cash and shares, if any,
results in an increase to the amount of cash to be paid to Holders, the Company will pay such increase in cash, and if such increased amount results in an increase to the number of shares of Common Stock, the Company will deliver such increase by
delivering Reference Property based on such increased number of shares. 
 (ii) If the last day of the applicable Observation
Period related to Notes surrendered for conversion is on or following the third scheduled Trading Day preceding the Effective Date of such Fundamental Change, the Company will satisfy the Conversion Obligation with respect to each $1,000 principal
amount of Notes tendered for conversion as described in Section 4.01(b) (based on the Conversion Rate as increased by the Additional Shares pursuant to Section 4.01(e) above) on the later to occur of (1) the Effective Date of the
Fundamental Change and (2) the third Trading Day immediately following the last day of the applicable Observation Period. 
 (c) Before
any Holder of a Note shall be entitled to convert the same as set forth above, such Holder shall (1) in the case of a Global Security, comply with the procedures of the Depositary in effect at that time and, if required, pay funds equal to
interest payable on the next Interest Payment Date to which such Holder is not entitled as set forth in Section 4.02(i) and, if required, pay all taxes or duties, if any, and (2) in the case of a Note issued in certificated form,
(A) complete and manually sign and deliver an irrevocable written notice to the Conversion Agent in the form on the reverse of such certificated Note (or a facsimile thereof) (a “Notice of Conversion”) at the office of the
Conversion Agent and shall state in writing therein the principal amount of Notes to be 
  

 19 

 converted and the name or names (with addresses) in which such Holder wishes the certificate or certificates for any
shares of Common Stock, if any, to be delivered upon settlement of the Conversion Obligation to be registered, (B) surrender such Notes, duly endorsed to the Company or in blank (and accompanied by appropriate endorsement and transfer
documents), at the office of the Conversion Agent, (C) if required, pay funds equal to interest payable on the next Interest Payment Date to which such Holder is not entitled as set forth in Section 4.02(i), and (D) if required, pay
all taxes or duties, if any. A Note shall be deemed to have been converted immediately prior to the close of business on the date (the “Conversion Date”) that the Holder has complied with the requirements set forth in this
Section 4.02(c). 
 No Notice of Conversion with respect to any Notes may be tendered by a Holder thereof if such Holder has also
tendered a Repurchase Notice and not validly withdrawn such Repurchase Notice in accordance with the applicable provisions of Section 5.03. 
 If more than one Note shall be surrendered for conversion at one time by the same Holder, the Conversion Obligation with respect to such Notes, if any, that shall be payable upon conversion shall be computed on the basis of the aggregate
principal amount of the Notes (or specified portions thereof to the extent permitted thereby) so surrendered. 
 (d) Delivery of the amounts
owing in satisfaction of the Conversion Obligation shall be made by the Company in no event later than the date specified in Section 4.02(a), except to the extent specified in Section 4.02(b). The Company shall make such delivery by paying
the cash amount owed to the Conversion Agent or to the Holder of the Note surrendered for conversion, or such Holder’s nominee or nominees, and by issuing, or causing to be issued, and delivering to the Conversion Agent or to such Holder, or
such Holder’s nominee or nominees, certificates or a book-entry transfer through the Depositary for the number of full shares of Common Stock, if any, to which such Holder shall be entitled as part of such Conversion Obligation (together with
any cash in lieu of fractional shares). 
 (e) In case any Note shall be surrendered for partial conversion, the Company shall execute and
the Trustee shall authenticate and deliver to or upon the written order of the Holder of the Note so surrendered, without charge to such Holder, a new Note or Notes in authorized denominations in an aggregate principal amount equal to the
unconverted portion of the surrendered Notes. 
 (f) If a Holder submits a Note for conversion, the Company shall pay all stamp and other
duties, if any, which may be imposed by the United States or any political subdivision thereof or taxing authority thereof or therein with respect to the issuance of shares of Common Stock, if any, upon the conversion. However, the Holder shall pay
any such tax which is due because the Holder requests any shares of Common Stock to be issued in a name other than the 
  

 20 

 Holder’s name. The Conversion Agent may refuse to deliver the certificates representing the shares of Common Stock
being issued in a name other than the Holder’s name until the Trustee receives a sum sufficient to pay any tax which will be due because the shares are to be issued in a name other than the Holder’s name. Nothing herein shall preclude any
tax withholding required by law or regulations. 
 (g) Except as provided in Section 4.03, no adjustment shall be made for dividends on
any shares issued upon the conversion of any Note as provided in this Article. 
 (h) Upon the conversion of an interest in a Global Note,
the Trustee, or the Custodian at the direction of the Trustee, shall make a notation on such Global Note as to the reduction in the principal amount represented thereby. The Company shall notify the Trustee in writing of any conversion of Notes
effected through any Conversion Agent other than the Trustee. 
 (i) Upon conversion, a Holder will not receive any separate cash payment for
accrued and unpaid interest except as set forth below. The Company’s settlement of the Conversion Obligations as described above shall be deemed to satisfy its obligation to pay the principal amount of the Note and accrued and unpaid interest
to the Conversion Date. As a result, accrued and unpaid interest to the Conversion Date shall be deemed to be paid in full rather than cancelled, extinguished or forfeited. Notwithstanding the preceding sentence, if Notes are converted after the
close of business on a Regular Record date, Holders of such Notes as of the close of business on the Regular Record date will receive the interest payable on such Notes on the corresponding Interest Payment Date notwithstanding the conversion. Notes
surrendered for conversion during the period from the close of business on any Regular Record Date to the opening of business on the corresponding Interest Payment Date must be accompanied by payment of an amount equal to the interest payable on the
Notes so converted; provided, however, that no such payment need be made (i) if the Company has specified a Designated Event Purchase Date that is after a Regular Record Date and on or prior to the corresponding Interest Payment Date; or
(ii) to the extent of any overdue interest existing at the time of conversion with respect to such Note. Except as described above, no payment or adjustment will be made for accrued interest on converted Notes. 
 (j) The Person in whose name the certificate for any shares of Common Stock issued upon conversion is registered shall be treated as a stockholder of
record on and after the Conversion Date; provided, however, that no surrender of Notes on any date when the stock transfer books of the Company shall be closed shall be effective to constitute the Person or Persons entitled to receive the
shares of Common Stock upon such conversion as the record holder or holders of such shares of Common Stock on such date, but such surrender shall be effective to constitute the Person or Persons entitled to receive such shares of Common Stock as the
record holder or holders thereof for all purposes at the close of business on 
  

 21 

 the next succeeding day on which such stock transfer books are open; such conversion shall be at the Conversion Rate in
effect on the date that such Notes shall have been surrendered for conversion, as if the stock transfer books of the Company had not been closed. Upon conversion of Notes, such Person shall no longer be a Holder. 
 (k) No fractional shares of Common Stock shall be issued upon conversion of any Note or Notes. If more than one Note shall be surrendered for conversion
at one time by the same Holder, the number of full shares that shall be issued upon conversion thereof shall be computed on the basis of the aggregate principal amount of the Notes (or specified portions thereof) so surrendered. Instead of any
fractional share of Common Stock that would otherwise be issued upon conversion of any Note or Notes (or specified portions thereof), the Company shall pay a cash adjustment in respect of such fraction (calculated to the nearest one-100th of a
share) in an amount equal to the same fraction of the Closing Price of the Common Stock on the last day of the applicable Observation Period. 
 Section 4.03. Adjustment of Conversion Rate. The Conversion Rate shall be adjusted from time to time by the Company as follows: 
 (a) In case the Company shall issue shares of Common Stock as a dividend or distribution to holders of all or substantially all of the outstanding Common Stock, or shall effect a subdivision into a greater number of shares of Common Stock
or combination into a lesser number of shares of Common Stock, the Conversion Rate shall be adjusted based on the following formula: 
  

					
	CR1=CR0 x  	  	OS1  	  	
	  	OS0  	  	

 where 
  

					
	CR0	  	=	  	the Conversion Rate in effect immediately prior to the Ex-Dividend Date for such dividend or distribution or the effective date of such subdivision or combination, as the case may
be;
			
	CR1	  	=	  	the Conversion Rate in effect immediately after the Ex-Dividend Date for such dividend or distribution or the effective date of such subdivision or combination, as the case may
be;
			
	OS0	  	=	  	the number of shares of Common Stock outstanding immediately prior to the Ex-Dividend Date for such dividend or distribution or the effective date of such subdivision or combination, as the
case may be;

  

 22 

					
	OS1	  	=	  	the number of shares of Common Stock outstanding immediately after the Ex-Dividend Date for such dividend or distribution or the effective date of such subdivision or combination, as the case
may be.

 Such adjustment shall become effective immediately after 9:00 a.m., New York City time, on the Business Day
following the Record Date fixed for such determination. If any dividend or distribution of the type described in this Section 4.03(a) is declared but not so paid or made, or the outstanding shares of Common Stock are not subdivided or combined,
as the case may be, the Conversion Rate shall be immediately readjusted, effective as of the date the Board of Directors determines not to pay such dividend or distribution, or subdivide or combine the outstanding shares of Common Stock, as the case
may be, to the Conversion Rate that would then be in effect if such dividend, distribution, subdivision or combination had not been declared. 
 (b) In case the Company shall issue to all or substantially all holders of its outstanding shares of Common Stock rights or warrants entitling them (for a period expiring within sixty (60) calendar days after the issuance thereof) to
subscribe for or purchase shares of Common Stock at a price per share less than the Closing Price of the Common Stock on the Business Day immediately preceding the date of announcement of such issuance, the Conversion Rate shall be adjusted based on
the following formula: 
  

					
	CR1=CR0 x  	  	OS0+ X    	  	
	  	OS0+ Y    	  	

 where 
  

					
	CR0	  	=	  	the Conversion Rate in effect immediately prior to the Ex-Dividend Date for such event;
			
	CR1	  	=	  	the Conversion Rate in effect immediately after the Ex-Dividend Date for such event;
			
	OS0	  	=	  	the number of shares of Common Stock outstanding immediately prior to the Ex-Dividend Date for such event;
			
	X	  	=	  	the total number of shares of Common Stock issuable pursuant to such rights, warrants or convertible securities; and
			
	Y	  	=	  	the number of shares of Common Stock equal to the aggregate price payable to exercise or convert such rights, warrants or convertible securities divided by the average of the Closing Prices
of Common Stock over the ten consecutive Trading Day period ending on the Business Day immediately preceding the Ex-Dividend Date relating to such distribution.

  

 23 

 Such adjustment shall be successively made whenever any such rights, warrants or convertible securities are issued and
shall become effective immediately after 9:00 a.m., New York City time, on the Business Day following the date fixed for such determination. If such rights, warrants or convertible securities are not so issued, the Conversion Rate shall again be
adjusted to be the Conversion Rate that would then be in effect if such Record Date for such distribution had not been fixed. To the extent that shares of Common Stock are not delivered after the expiration of such rights, warrants or convertible
securities, the Conversion Rate shall be readjusted to the Conversion Rate that would then be in effect had the adjustments made upon the issuance of such rights or warrants been made on the basis of delivery of only the number of shares of Common
Stock actually delivered. 
 In determining whether any rights, warrants or convertible securities entitle the holders to subscribe for or
purchase shares of Common Stock at less than such Closing Price, and in determining the aggregate offering price of such shares of Common Stock, there shall be taken into account any consideration received by the Company for such rights or warrants
and any amount payable on exercise or conversion thereof, the value of such consideration, if other than cash, to be determined by the Board of Directors. 
 (c) In case the Company shall, by dividend or otherwise, distribute to all or substantially all holders of its Common Stock shares of any class of Capital Stock of the Company (other than Common Stock as covered by
Section 4.03(a)), evidences of its indebtedness or other assets or property of the Company (including securities, but excluding dividends and distributions covered by Section 4.03(b) or Section 4.03(d) and distributions described
below in this paragraph (c) with respect to Spin-Offs) (any of such shares of Capital Stock, indebtedness, or other asset or property hereinafter in this Section 4.03(c) called the “Distributed Property”), then, in each
such case the Conversion Rate shall be adjusted based on the following formula: 
  

					
	CR1=CR0 x  	  	SP0	  	
	  	SP0 – FMV	  	

 where 
  

					
	CR0	  	=	  	the Conversion Rate in effect immediately prior to the Ex-Dividend Date for such distribution;
			
	CR1	  	=	  	the Conversion Rate in effect immediately after the Ex-Dividend Date for such distribution;
			
	SP0	  	=	  	the average of the Closing Prices of the Common Stock over the ten consecutive Trading Day period ending on the Business Day immediately preceding the Ex-Dividend Date relating to such
distribution; and

  

 24 

					
	FMV	  	=	  	the fair market value (as determined by the Board of Directors) of the shares of Capital Stock, evidences of indebtedness, assets or property distributed with respect to each outstanding
share of Common Stock on the Ex-Dividend Date relating to such distribution.

 Such adjustment shall become effective immediately prior to 4:00 a.m., New York City time, on the Business Day
following the date fixed for the determination of stockholders entitled to receive such distribution; provided that if the then fair market value (as so determined) of the portion of the Distributed Property so distributed applicable to one
share of Common Stock is equal to or greater than SP0 as set forth above, in lieu of the foregoing adjustment,
adequate provision shall be made so that each Holder shall have the right to receive, for each $1,000 principal amount of Notes upon conversion, the amount of Distributed Property such Holder would have received had such Holder owned a number of
shares of Common Stock equal to the Conversion Rate on the Record Date. If such dividend or distribution is not so paid or made, the Conversion Rate shall again be adjusted to be the Conversion Rate that would then be in effect if such dividend or
distribution had not been declared. If the Board of Directors determines the fair market value of any distribution for purposes of this Section 4.03(c) by reference to the actual or when issued trading market for any securities, it must in
doing so consider the prices in such market over the same period used in determining SP0 above. 
 With respect to an adjustment pursuant to this Section 4.03(c) where there has been a payment of a dividend or other distribution on the Common
Stock or shares of Capital Stock of any class or series, or similar equity interest, of or relating to a Subsidiary or other business unit (a “Spin-Off”), the Conversion Rate in effect immediately before the close of business on the
Record Date fixed for the determination of stockholders entitled to receive the distribution will be increased based on the following formula: 
  

					
	CR1=CR0 x  	  	FMV0 + MP0	  	
	  	MP0	  	

 where 
  

					
	CR0	  	=	  	the Conversion Rate in effect immediately prior to such distribution;
			
	CR1	  	=	  	the Conversion Rate in effect immediately after such distribution;
			
	FMV0	  	=	  	the average of the Closing Prices of the Capital Stock or similar equity interest distributed to holders of Common Stock applicable to one share of Common Stock over the first ten (10)
consecutive Trading Day period after the effective date of the Spin-Off; and

  

 25 

					
	MP0	  	=	  	the average of the Closing Prices of Common Stock over the first ten (10) consecutive Trading Day period after the effective date of the Spin-Off.

 Such adjustment shall occur on the tenth (10th) Trading Day from, and including, the effective date of the Spin-Off; provided that in respect of any conversion within the ten (10) Trading
Days following the effective date of any Spin-Off, references within this paragraph (c) to ten (10) days shall be deemed replaced with such lesser number of Trading Days as have elapsed between such Spin-Off and the conversion date in
determining the applicable Conversion Rate. 
 Rights or warrants distributed by the Company to all holders of Common Stock, entitling the
holders thereof to subscribe for or purchase shares of the Company’s Capital Stock, including Common Stock (either initially or under certain circumstances), which rights or warrants, until the occurrence of a specified event or events
(“Trigger Event”): (i) are deemed to be transferred with such shares of Common Stock; (ii) are not exercisable; and (iii) are also issued in respect of future issuances of Common Stock, shall be deemed not to have
been distributed for purposes of this Section 4.03 (and no adjustment to the Conversion Rate under this Section 4.03 will be required) until the occurrence of the earliest Trigger Event, whereupon such rights and warrants shall be deemed
to have been distributed and an appropriate adjustment (if any is required) to the Conversion Rate shall be made under this Section 4.03(c). If any such right or warrant, including any such existing rights or warrants distributed prior to the
date of this Supplemental Indenture, are subject to events, upon the occurrence of which such rights or warrants become exercisable to purchase different securities, evidences of indebtedness or other assets, then the date of the occurrence of any
and each such event shall be deemed to be the date of distribution and record date with respect to new rights or warrants with such rights (and a termination or expiration of the existing rights or warrants without exercise by any of the holders
thereof). In addition, in the event of any distribution (or deemed distribution) of rights or warrants, or any Trigger Event or other event (of the type described in the preceding sentence) with respect thereto that was counted for purposes of
calculating a distribution amount for which an adjustment to the Conversion Rate under this Section 4.03 was made, (1) in the case of any such rights or warrants that shall all have been redeemed or repurchased without exercise by any
holders thereof, the Conversion Rate shall be readjusted upon such final redemption or repurchase to give effect to such distribution or Trigger Event, as the case may be, as though it were a cash distribution, equal to the per share redemption or
repurchase price received by a holder or holders of Common Stock with respect to such rights or warrants (assuming such holder had retained such rights or warrants), made to all holders of Common Stock as of the date of such redemption or
repurchase, and (2) in the case of such rights or warrants that shall have expired or been terminated without exercise by any holders thereof, the Conversion Rate shall be readjusted as if such rights and warrants had not been issued.

  

 26 

 For purposes of this Section 4.03(c), Section 4.03(a) and Section 4.03(b), any dividend or
distribution to which this Section 4.03(c) is applicable that also includes shares of Common Stock to which Section 4.03(a) applies or rights or warrants to subscribe for or purchase shares of Common Stock to which Section 4.03(a) or
Section 4.03(b) applies (or both), shall be deemed instead to be (1) a dividend or distribution of the evidences of indebtedness, assets or shares of capital stock other than such shares of Common Stock or rights or warrants to which
Section 4.03(b) applies (and any Conversion Rate adjustment required by this Section 4.03(c) with respect to such dividend or distribution shall then be made) immediately followed by (2) a dividend or distribution of such shares of
Common Stock or such rights or warrants (and any further Conversion Rate adjustment required by Section 4.03(a) and Section 4.03(b) with respect to such dividend or distribution shall then be made), except (A) the record date of such
dividend or distribution shall be substituted as “the Record Date” and “the date fixed for such determination” within the meaning of Section 4.03(a) and Section 4.03(b) and (B) any shares of Common Stock included
in such dividend or distribution shall not be deemed “outstanding immediately prior to such event” within the meaning of Section 4.03(a). 
 (d) In case the Company shall pay a dividend or make a distribution consisting exclusively of cash to all or substantially all holders of its Common Stock (but only if such dividends and distributions, combined with
all other dividends and distributions to all or substantially all holders of the Common Stock made within such fiscal quarter exceed the Dividend Threshold Amount), the Conversion Rate shall be adjusted based on the following formula: 
  

					
	CR1=CR0 x  	  	SP0 – C0	  	
	  	SP0 – C1	  	

 where 
  

					
	CR0	  	=	  	the Conversion Rate in effect immediately prior to the Ex-Dividend Date for such distribution;
			
	CR1	  	=	  	the Conversion Rate in effect immediately after the Ex-Dividend Date for such distribution;
			
	SP0	  	=	  	the Closing Price of the Common Stock on the Trading Day immediately preceding the Ex-Dividend Date relating to such distribution;
			
	C0	  	=	  	the Dividend Threshold Amount; and
			
	C1	  	=	  	the amount in cash per share the Company distributes to holders of Common Stock.

 Such adjustment shall become effective immediately after the close of business on the Record Date for such
dividend or distribution; provided that if the portion of 
  

 27 

 the cash so distributed applicable to one share of Common Stock is equal to or greater than SP0 as above, in lieu of the foregoing adjustment, adequate provision shall be made so that each Holder shall have the right to
receive upon conversion of a Note (or any portion thereof) the amount of cash such Holder would have received had such Holder owned a number of shares equal to the Conversion Rate on the Record Date. If such dividend or distribution is not so paid
or made, the Conversion Rate shall again be adjusted to be the Conversion Rate that would then be in effect if such dividend or distribution had not been declared. 
 Whenever the Conversion Rate is adjusted hereunder or under the Notes, the Dividend Threshold Amount shall be increased or decreased by multiplying the Dividend Threshold Amount at such time by a fraction, the
numerator of which is the Conversion Rate prior to such adjustment and the denominator of which is the Conversion Rate following such adjustment. For the avoidance of doubt, the Conversion Rate may be increased or decreased pursuant to the
application of this Section 4.03(d). 
 For the avoidance of doubt, for purposes of this Section 4.03(d), in the event of any
reclassification of the Common Stock, as a result of which the Notes become convertible into more than one class of Common Stock, if an adjustment to the Conversion Rate is required pursuant to this Section 4.03(d), references in this Section
to one share of Common Stock or Closing Price of one share of Common Stock shall be deemed to refer to a unit or to the price of a unit consisting of the number of shares of each class of Common Stock into which the Notes are then convertible equal
to the numbers of shares of such class issued in respect of one share of Common Stock in such reclassification. The above provisions of this paragraph shall similarly apply to successive reclassifications. 
 (e) In case the Company or any of its Subsidiaries make a payment in respect of a tender offer or exchange offer for all or any portion of the Common
Stock, to the extent that the cash and value of any other consideration included in the payment per share of Common Stock exceeds the Closing Price of the Common Stock on the Trading Day next succeeding the last date on which tenders or exchanges
may be made pursuant to such tender or exchange offer (as it may be amended), the Conversion Rate shall be increased based on the following formula: 
  

					
	CR1=CR0 x  	  	AC + (SP1 x OS1)    	 	
	  	OS0 x SP1    	 	

 where 
  

					
	CR0	  	=	  	the Conversion Rate in effect on the date such tender or exchange offer expires;
			
	CR1	  	=	  	the Conversion Rate in effect on the day next succeeding the date such tender or exchange offer expires;

  

 28 

					
	AC	  	=	  	the aggregate value of all cash and any other consideration (as determined by the Board of Directors) paid or payable for shares purchased in such tender or exchange offer;
			
	OS0	  	=	  	the number of shares of Common Stock outstanding immediately prior to the date such tender or exchange offer expires;
			
	OS1	  	=	  	the number of shares of Common Stock outstanding immediately after the date such tender or exchange offer expires; and
			
	SP1	  	=	  	the average of the Closing Prices of Common Stock on the Trading Day next succeeding the date such tender or exchange offer expires,

 such adjustment to become effective immediately prior to the opening of business on the day following the last
date on which tenders or exchanges may be made pursuant to such tender or exchange offer. If the Company is obligated to purchase shares pursuant to any such tender or exchange offer, but the Company is permanently prevented by applicable law from
effecting all or any such purchases or all or any portion of such purchases are rescinded, the Conversion Rate shall again be adjusted to be the Conversion Rate that would then be in effect if such tender or exchange offer had not been made or had
only been made in respect of the purchases that had been effected. No adjustment to the Conversion Rate will be made if the application of the foregoing formulae would result in a decrease in the Conversion Rate. 
 (f) For purposes of this Section 4.03 the term “Record Date” shall mean, with respect to any dividend, distribution or other
transaction or event in which the holders of Common Stock have the right to receive any cash, securities or other property or in which the Common Stock (or other applicable security) is exchanged for or converted into any combination of cash,
securities or other property, the date fixed for determination of stockholders entitled to receive such cash, securities or other property (whether such date is fixed by the Board of Directors or by statute, contract or otherwise). 
 (g) In addition to those required by clauses (a), (b), (c), (d), and (e) of this Section 4.03, and to the extent permitted by applicable law,
the Company from time to time may increase the Conversion Rate by any amount for a period of at least twenty (20) calendar days if the Board of Directors determines that such increase would be in the Company’s best interest. In addition,
the Company may also (but is not required to) increase the Conversion Rate to avoid or diminish any income tax to holders of Common Stock or rights to purchase Common Stock in connection with any dividend or distribution of shares (or rights to
acquire shares) or similar event. Whenever the Conversion Rate is increased pursuant to the preceding sentence, the Company shall mail to the 
  

 29 

 Holder of each Note at his last address appearing on the Security Register provided for in Section 305 of the Base
Indenture a notice of the increase at least fifteen (15) days prior to the date the increased Conversion Rate takes effect, and such notice shall state the increased Conversion Rate and the period during which it will be in effect. 

(h) All calculations and other determinations under this Article 4 shall be made by the Company and shall be made to the nearest cent or to the
nearest one-ten thousandth (1/10,000) of a share, as the case may be. No adjustment shall be made for the Company’s issuance of Common Stock or convertible or exchangeable securities or rights to purchase Common Stock or convertible or
exchangeable securities, other than as provided in this Section 4.03, and no adjustment shall be made for a change in par value of the Common stock of for accrued and unpaid interest, including Additional Interest, Reporting Interest and
Contingent Interest, if any. No adjustment shall be made to the Conversion Rate unless such adjustment would require a change of at least 1% in the Conversion Rate then in effect at such time. The Company shall carry forward any adjustments that are
less than 1% of the Conversion Rate and make such carried forward adjustments, regardless of whether the aggregate adjustment is less than 1% (1) within one year of the first such adjustment carried forward, (2) upon a Designated Event,
(3) upon any call of the Notes for redemption, and (4) upon maturity. 
 (i) Whenever the Conversion Rate is adjusted as herein
provided, the Company shall promptly file with the Trustee and any Conversion Agent other than the Trustee an Officer’s Certificate setting forth the Conversion Rate after such adjustment and setting forth a brief statement of the facts
requiring such adjustment. The Trustee and Conversion Agent may conclusively rely on the accuracy of the Conversion Rate adjustment provided by the Company. Unless and until a Responsible Officer of the Trustee shall have received such
Officer’s Certificate, the Trustee shall not be deemed to have knowledge of any adjustment of the Conversion Rate and may assume without inquiry that the last Conversion Rate of which it has knowledge is still in effect. Promptly after delivery
of such certificate, the Company shall prepare a notice of such adjustment of the Conversion Rate setting forth the adjusted Conversion Rate and the date on which each adjustment becomes effective and shall mail such notice of such adjustment of the
Conversion Rate to the Holder of each Note at his last address appearing on the Security Register provided for in Section 305 of the Base Indenture, within twenty (20) days of the effective date of such adjustment. Failure to deliver such
notice shall not affect the legality or validity of any such adjustment. 
 (j) In any case in which this Section 4.03 provides that an
adjustment shall become effective immediately after (1) a record date or Record Date for an event, (2) the date fixed for the determination of stockholders entitled to receive a dividend or distribution pursuant to Section 4.03(a),
(3) a date fixed for the determination of stockholders entitled to receive rights or warrants pursuant to Section 4.03(b), or (4) the last date on which tenders or exchanges may be made 
  

 30 

 pursuant to any tender or exchange offer pursuant to Section 4.03(e) (each an “Adjustment Determination
Date”), the Company may elect to defer until the occurrence of the applicable Adjustment Event (as hereinafter defined) (x) issuing to the Holder of any Note converted after such Adjustment Determination Date and before the occurrence
of such Adjustment Event, the additional cash and, if applicable, shares of Common Stock or other securities issuable upon such conversion by reason of the adjustment required by such Adjustment Event over and above the amounts deliverable upon such
conversion before giving effect to such adjustment and (y) paying to such Holder any amount in cash in lieu of any fraction pursuant to Section 4.03. For purposes of this Section 4.03(j), the term “Adjustment Event”
shall mean: 
 (i) in any case referred to in clause (1) hereof, the occurrence of such event, 
 (ii) in any case referred to in clause (2) hereof, the date any such dividend or distribution is paid or made, 
 (iii) in any case referred to in clause (3) hereof, the date of expiration of such rights or warrants, and 
 (iv) in any case referred to in clause (4) hereof, the date a sale or exchange of Common Stock pursuant to such tender or exchange
offer is consummated and becomes irrevocable. 
 (k) For purposes of this Section 4.03, the number of shares of Common Stock at any time
outstanding shall not include shares held in the treasury of the Company but shall include shares issuable in respect of scrip certificates issued in lieu of fractions of shares of Common Stock. 
 (l) For the avoidance of doubt, if a Holder converts Notes prior to the effective date of a Fundamental Change, and the Fundamental Change does not
occur, the Holder will not be entitled to an increased Conversion Rate in connection with such conversion. 
 (m) The Company will not be
required to make any adjustment to the Conversion Rate pursuant to this Section 4.03 if Holders participate, as a result of holding the Notes, in any transaction that would otherwise trigger such adjustment. 
 Section 4.04. Shares To Be Fully Paid. The Company shall provide, free from preemptive rights, out of its authorized but unissued shares or
shares held in treasury, sufficient shares of Common Stock to provide for conversion of the Notes from time to time as such Notes are presented for conversion. 
 Section 4.05. Effect of Reclassification, Consolidation, Merger or Sale. If any of the following events occur, namely (i) any reclassification or change of the outstanding shares of Common Stock
(other than a change in par value, or from 
  

 31 

 par value to no par value, or from no par value to par value, or as a result of a split, subdivision or combination),
(ii) any consolidation, merger or combination of the Company with another Person, or (iii) any sale or conveyance of all or substantially all of the property and assets of the Company to any other Person, in either case as a result of
which holders of Common Stock shall be entitled to receive cash, securities or other property or assets with respect to or in exchange for such Common Stock (any such event a “Merger Event”), then: 
 (a) the Company or the successor or purchasing Person, as the case may be, shall execute with the Trustee a supplemental indenture (which shall comply
with the Trust Indenture Act as in force at the date of execution of such supplemental indenture if such supplemental indenture is then required to so comply) permitted under Section 901 of the Base Indenture providing for the conversion and
settlement of the Notes as set forth in this Supplemental Indenture. Such supplemental indenture shall provide for adjustments which shall be as nearly equivalent as may be practicable to the adjustments provided for in this Article and the Trustee
may conclusively rely on the determination by the Company of the equivalency of such adjustments. If, in the case of any Merger Event, the Reference Property includes shares of stock or other securities and assets of a corporation other than the
successor or purchasing corporation, as the case may be, in such reclassification, change, consolidation, merger, combination, sale or conveyance, then such supplemental indenture shall also be executed by such other corporation and shall contain
such additional provisions to protect the interests of the Holders of the Notes as the Board of Directors shall reasonably consider necessary by reason of the foregoing, including to the extent required by the Board of Directors and practicable the
provisions providing for the repurchase rights set forth in Article 5 herein. 
 In the event the Company shall execute a supplemental
indenture pursuant to this Section 4.05, the Company shall promptly file with the Trustee an Officer’s Certificate briefly stating the reasons therefore, the kind or amount of cash, securities or property or asset that will constitute the
Reference Property after any such Merger Event, any adjustment to be made with respect thereto and that all conditions precedent have been complied with, and shall promptly mail notice thereof to all Holders. 
 (b) Notwithstanding the provisions of Section 4.02(a) and Section 4.02(b), and subject to the provisions of Section 4.01, at the effective
time of such Merger Event, the right to convert each $1,000 principal amount of Notes will be changed to a right to convert such Note by reference to the kind and amount of cash, securities or other property or assets that a holder of a number of
shares of Common Stock equal to the Conversion Rate immediately prior to such transaction would have owned or been entitled to receive (the “Reference Property”) such that from and after the effective time of such transaction, a
Holder will be entitled thereafter to convert its Notes into cash (up to the aggregate principal amount thereof) and the same type (and in the same proportion) of Reference Property, based on the Daily Settlement Amounts of 
  

 32 

 Reference Property in an amount equal to the applicable Conversion Rate, as described under Section 4.02(b). For
purposes of determining the constitution of Reference Property, the type and amount of consideration that a holder of Common Stock would have been entitled to in the case of reclassifications, consolidations, mergers, sales or conveyance of assets
or other transactions that cause the Common Stock to be converted into the right to receive more than a single type of consideration (determined based in part upon any form of stockholder election) will be deemed to be the weighted average of the
types and amounts of consideration received by the holders of Common Stock that affirmatively make such an election. The Company shall not become a party to any such transaction unless its terms are consistent with the preceding. None of the
foregoing provisions shall affect the right of a Holder of Notes to convert its Notes in accordance with the provisions of Article 4 hereof prior to the effective date. 
 (c) The Company shall cause notice of the execution of such supplemental indenture to be mailed to each Holder, at his address appearing on the Security Register provided for in this Indenture, within twenty
(20) days after execution thereof Failure to deliver such notice shall not affect the legality or validity of such supplemental indenture. 
 (d) The above provisions of this Section shall similarly apply to successive Merger Events. 
 Section 4.06. Certain
Covenants.  
 (a) Before taking any action which would cause an adjustment reducing the Conversion Rate below the then par value, if any,
of the shares of Common Stock issuable upon conversion of the Notes, the Company will take all corporate action which may, in the opinion of its counsel, be necessary in order that the Company may validly and legally issue shares of such Common
Stock at such adjusted Conversion Rate. 
 The Company covenants that all shares of Common Stock issued upon conversion of Notes will be
fully paid and non-assessable by the Company and free from all taxes, liens and changes with respect to the issue thereof. 
 (b) The Company
covenants that, if any shares of Common Stock to be provided for the purpose of conversion of Notes hereunder require registration with or approval of any governmental authority under any federal or state law before such shares may be validly issued
upon conversion, the Company will in good faith and as expeditiously as possible, to the extent then permitted by the rules and interpretations of the Commission (or any successor thereto), endeavor to secure such registration or approval, as the
case may be. 
 (c) The Company further covenants that if at any time the Common Stock shall be listed on any other national securities
exchange or automated 
  

 33 

 quotation system the Company will, if permitted and required by the rules of such exchange or automated quotation system,
list and keep listed, so long as the Common Stock shall be so listed on such exchange or automated quotation system, all Common Stock issuable upon conversion of the Notes. 
 Section 4.07. Responsibility of Trustee. Notwithstanding any provision of this Indenture to the contrary, the Trustee and any other
Conversion Agent shall not at any time be under any duty or responsibility to any Holder to determine the Conversion Rate or whether any facts exist which may require any adjustment of the Conversion Rate, or with respect to the nature or extent or
calculation of any such adjustment when made, or with respect to the method employed, or herein or in any supplemental indenture provided to be employed, in making the same. The Trustee and any other Conversion Agent shall not be accountable with
respect to the validity or value (or the kind or amount) of any shares of Common Stock, or of any securities or property, which may at any time be issued or delivered upon the conversion of any Note; and the Trustee and any other Conversion Agent
make no representations with respect thereto. Neither the Trustee nor any Conversion Agent shall be responsible for any failure of the Company to issue, transfer or deliver any shares of Common Stock or stock certificates or other securities or
property or cash upon the surrender of any Note for the purpose of conversion or to comply with any of the duties, responsibilities or covenants of the Company contained in this Article. 
 Without limiting the generality of the foregoing, neither the Trustee nor any Conversion Agent shall be under any responsibility to determine the
correctness of any provisions contained in any supplemental indenture entered into pursuant to Section 4.05 relating either to the kind or amount of shares of stock or securities or property (including cash) receivable by Holders upon the
conversion of their Notes after any event referred to in such Section 4.05 or to any adjustment to be made with respect thereto, but, subject to the provisions of Section 601 of the Base Indenture, may accept as conclusive evidence of the
correctness of any such provisions, and shall be protected in relying upon, the Officer’s Certificate (which the Company shall be obligated to file with the Trustee prior to the execution of any such supplemental indenture) with respect
thereto. 
 Section 4.08. Notice to Holders Prior to Certain Actions. In case: 
 (a) the Company shall declare a dividend (or any other distribution) on its Common Stock that would require an adjustment in the Conversion Rate pursuant
to Section 4.03; or 
 (b) the Company shall authorize the granting to all of the holders of its Common Stock of rights or warrants to
subscribe for or purchase any share of any class or any other rights or warrants; or 
  

 34 

 (c) of any reclassification of the Common Stock of the Company (other than a subdivision or combination
of its outstanding Common Stock, or a change in par value, or from par value to no par value, or from no par value to par value), or of any consolidation or merger to which the Company is a party and for which approval of any shareholders of the
Company is required, or of the sale or transfer of all or substantially all of the assets of the Company; or 
 (d) of the voluntary or
involuntary dissolution, liquidation or winding-up of the Company; 
 the Company shall cause to be filed with the Trustee and to be mailed to each Holder at
his address appearing on the Security Register, provided for in Section 305 of the Base Indenture, as promptly as possible but in any event at least twenty (20) days prior to the applicable date specified in clause (x) or
(y) below, as the case may be, a notice stating (x) the date on which a record is to be taken for the purpose of such dividend, distribution or rights or warrants, or, if a record is not to be taken, the date as of which the holders of
Common Stock of record to be entitled to such dividend, distribution or rights are to be determined, or (y) the date on which such reclassification, consolidation, merger, sale, transfer, dissolution, liquidation or winding-up is expected to
become effective or occur, and the date as of which it is expected that holders of Common Stock of record shall be entitled to exchange their Common Stock for securities or other property deliverable upon such reclassification, consolidation,
merger, sale, transfer, dissolution, liquidation or winding-up. Failure to give such notice, or any defect therein, shall not affect the legality or validity of such dividend, distribution, reclassification, consolidation, merger, sale, transfer,
dissolution, liquidation or winding-up. 
 Section 4.09. Shareholder Rights Plans. Upon conversion of the Notes, the Holders
shall receive, in addition to any shares of Common Stock issuable upon such conversion, the associated rights issued under the Rights Plan or under any future shareholder rights plan the Company adopts unless, prior to conversion, the rights have
separated from the Common Stock, expired, terminated or been redeemed or exchanged in accordance with the Rights Plan. If the Holders receive rights under such shareholder rights plans as described in the preceding sentence upon conversion of their
Notes, then no other adjustment pursuant to this Article 4 shall be made in connection with such shareholder rights plans. If, prior to conversion of a Note, such rights have separated from the Common Stock, then the provisions of
Section 4.03(c) shall apply. 
 ARTICLE 5 
 REPURCHASE OF NOTES AT OPTION OF HOLDERS 
 Section 5.01. Repurchase at Option of Holders on Specified Dates. On each of December 15, 2013, 2016, 2021, 2026 and 2031, each Holder
shall have 
  

 35 

 the right, at such Holder’s option, to require the Company to repurchase all of such Holder’s Notes or any
portion thereof that is a multiple of $1,000 principal amount, for cash on the date (the “Specified Purchase Date”) at a repurchase price equal to 100% of the principal amount thereof, together with accrued and unpaid interest
thereon to, but excluding, the Specified Purchase Date (the “Purchase Price”). 
 Section 5.02. Repurchase at Option
of Holders Upon a Designated Event. If a Designated Event occurs at any time, then each Holder shall have the right, at such Holder’s option, to require the Company to repurchase all of such Holder’s Notes or any portion thereof that
is a multiple of $1,000 principal amount, for cash on the date (the “Designated Event Repurchase Date”) specified by the Company that is not less than twenty (20) and not more than thirty five (35) Business Days after the
date of the Company Notice (as defined below) at a repurchase price equal to 100% of the principal amount thereof, together with accrued and unpaid interest thereon to, but excluding, the Designated Event Repurchase Date (unless the Designated Event
Repurchase Date is between a Regular Record Date and the corresponding Interest Payment Date) (the “Designated Event Repurchase Price”). 
 Section 5.03. Required Notes and Procedures.  
 (a) Repurchases of Notes under Sections 5.01 or
5.02 shall be made, at the option of the Holder thereof, upon: 
 (i) delivery to the Trustee (or other Paying Agent appointed
by the Company) by a Holder of a duly completed notice (the “Repurchase Notice”) in the form set forth on the reverse of the Note prior to the close of business on the Specified Purchase Date or Designated Event Repurchase Date, as
the case may be; and 
 (ii) delivery or book-entry transfer of the Notes to the Trustee (or other Paying Agent appointed by
the Company) at any time after delivery of the Repurchase Notice (together with all necessary endorsements) at the Corporate Trust Office of the Trustee (or other Paying Agent appointed by the Company) in the Borough of Manhattan, such delivery
being a condition to receipt by the Holder of the Purchase Price therefor; provided that such Purchase Price shall be so paid pursuant to this Article 5 only if the Note so delivered to the Trustee (or other Paying Agent appointed by the
Company) shall conform in all respects to the description thereof in the related Repurchase Notice. 
 The Repurchase Notice shall state:

 (A) if certificated, the certificate numbers of Notes to be delivered for repurchase; 
  

 36 

 (B) the portion of the principal amount of Notes to be repurchased, which must be $1,000
or a multiple thereof, and 
 (C) that the Notes are to be repurchased by the Company pursuant to the applicable provisions of
the Notes and the Indenture. 
 Any purchase by the Company contemplated pursuant to the provisions of this Article 5 shall be consummated by
the delivery of the consideration to be received by the Holder promptly following the later of the Specified Purchase Date or Designated Event Repurchase Date, as the case may be, and the time of the book-entry transfer or delivery of the Note.

 The Trustee (or other Paying Agent appointed by the Company) shall promptly notify the Company of the receipt by it of any Repurchase
Notice or written notice of withdrawal thereof in accordance with the provisions of Section 5.03(c). 
 Any Note that is to be
repurchased only in part shall be surrendered to the Trustee (with, if the Company or the Trustee so requires, due endorsement by, or a written instrument of transfer in form satisfactory to the Company and the Trustee duly executed by the Holder
thereof or his attorney duly authorized in writing), and the Company shall execute, and the Trustee shall authenticate and make available for delivery to the Holder of such Note without service charge, a new Note or Notes, containing identical terms
and conditions, each in an authorized denomination in aggregate principal amount equal to and in exchange for the unrepurchased portion of the principal of the Note so surrendered. 
 (b) On a date not less than twenty (20) Business Days prior to each Specified Purchase Date and on or before the tenth (10th) Business Day after the Effective Date of any Designated Event, the Company shall provide to all Holders of record of the
Notes and the Trustee and Paying Agent a notice (the “Company Notice”) of the occurrence of such Specified Purchase Date or Designated Event, as the case may be, and of the repurchase right at the option of the Holders arising as a
result thereof. Such mailing shall be by first class mail. Simultaneously with providing such Company Notice, the Company shall issue a press release containing the information on a nationally-recognized newswire or publish the information on the
Company’s website or through such other public medium as the Company may use at such time. 
 Each Company Notice shall specify: 
 (i) if applicable, the events causing the Designated Event and whether such Designated Event also constituted a Fundamental Change;

 (ii) if applicable, the date of the Designated Event; 
  

 37 

 (iii) the Specified Purchase Date or Designated Event Repurchase Date, as the case may
be, and the last date on which a Holder may exercise the repurchase right; 
 (iv) the Purchase Price or Designated Event
Repurchase Price, as applicable; 
 (v) the name and address of the Paying Agent and the Conversion Agent; 
 (vi) the applicable Conversion Rate and any adjustments to the applicable Conversion Rate; 
 (vii) that the Notes with respect to which a Repurchase Notice has been delivered by a Holder may be converted only if the Holder
withdraws the Repurchase Notice in accordance with the terms of the Indenture; 
 (viii) that the Holder must exercise the
repurchase right on or prior to the close of business on the Specified Purchase Date or Designated Event Repurchase Date, as the case may be (the “Expiration Time”); 
 (ix) that the Holder shall have the right to withdraw any Notes surrendered prior to the Expiration Time; and 
 (x) the procedures that Holders must follow to require the Company to repurchase their Notes. 
 No failure of the Company to give the foregoing notices and no defect therein shall limit the Holders’ repurchase rights or affect the validity of
the proceedings for the repurchase of the Notes pursuant to this Article 5. 
 (c) A Repurchase Notice may be withdrawn by means of a written
notice of withdrawal delivered to the Paying Agent in accordance with the Company Notice at any time prior to the close of business on the Business Day prior to the Specified Purchase Date or Designated Event Repurchase Date, as the case may be,
specifying: 
 (i) if certificated Notes have been issued, the certificate numbers of the withdrawn Notes, 
 (ii) the principal amount of the Note with respect to which such notice of withdrawal is being submitted, and 
 (iii) the principal amount, if any, of such Note that remains subject to the original Designated Event Repurchase Notice, which portion
must be in principal amounts of $1,000 or a multiple of $1,000; 
  

 38 

 provided, however, that if the Notes are not in certificated form, the notice must comply with appropriate
procedures of the Depositary. 
 (d) On or prior to 11:00 a.m. (New York City time) on the Business Day following the Specified Purchase Date
or Designated Event Repurchase Date, as the case may be, the Company will deposit with the Trustee (or other Paying Agent appointed by the Company or if the Company is acting as its own Paying Agent, set aside, segregate and hold in trust as
provided in Section 1003 of the Base Indenture) an amount of money sufficient to repurchase on the Specified Purchase Date or Designated Event Repurchase Date, as the case may be, all of the Notes to be repurchased on such date at the Purchase
Price or Designated Event Repurchase Price, as the case may be. Subject to receipt of funds and/or Notes by the Trustee (or other Paying Agent appointed by the Company), payment for Notes surrendered for repurchase (and not withdrawn) prior to the
Expiration Time will be made promptly after the later of (x) the Specified Purchase Date or Designated Event Repurchase Date, as the case may be, with respect to such Note (provided the Holder has satisfied the conditions to the payment
of the Purchase Price or Designated Event Repurchase Price, as the case may be, in Sections 5.01 or 5.02), and (y) the time of book-entry transfer or the delivery of such Note to the Trustee (or other Paying Agent appointed by the Company) by
the Holder thereof in the manner required by Section 5.01 or 5.02 hereof by mailing checks for the amount payable to the Holders of such Notes entitled thereto as they shall appear in the Security Register, provided, however, that
payments to the Depositary shall be made by wire transfer of immediately available funds to the account of the Depositary or its nominee. The Trustee shall, promptly after such payment and upon written demand by the Company, return to the Company
any funds in excess of the Purchaser Price or Designated Event Repurchase Price, as the case may be. 
 (e) If the Trustee (or other Paying
Agent appointed by the Company) holds money or securities sufficient to repurchase on the Specified Purchase Date or Designated Event Repurchase Date, as the case may be, all the Notes or portions thereof that are to be purchased as of the Business
Day following the Specified Purchase Date or Designated Event Repurchase Date, as the case may be, then on and after the Specified Purchase Date or Designated Event Repurchase Date, as the case may be (i) such Notes will cease to be
outstanding, (ii) interest will cease to accrue on such Notes, and (iii) all other rights of the Holders of such Notes will terminate, whether or not book-entry transfer of the Notes has been made or the Notes have been delivered to the
Trustee or Paying Agent, other than the right to receive the Purchase Price or Designated Event Repurchase Price, as applicable, upon delivery of the Notes. 
  

 39 

 ARTICLE 6 
 OPTIONAL REDEMPTION 
 Section 6.01. Right To Redeem. Prior to
December 20, 2013, the Notes will not be redeemable at the Company’s option. Beginning on December 20, 2013, the Company, at its option, may redeem the Securities in accordance with this Article 6 and Article XI of the Base Indenture
for cash at any time as a whole, or from time to time in part, at a redemption price equal to 100% of the principal amount of Notes to be redeemed plus any accrued and unpaid interest, on those Notes to, but excluding, the Redemption Date (the
“Redemption Price”). 
 In the event that the Company elects to redeem the Notes on a date that is on or after any Regular
Record Date but on or before the corresponding Interest Payment Date, the Company shall be required to pay any accrued and unpaid interest, to the same Holder to whom the Company pays the principal of such Note regardless of whether such Holder was
the registered Holder on the Regular Record Date immediately preceding such Redemption Date and, if the Holder to whom the Company pays the principal, interest, was not the registered Holder on the Regular Record Date, such payment shall be in lieu
of payment to the registered Holder on such Regular Record Date. 
 If the Company elects to redeem Notes, it shall notify the Trustee in
writing of the Redemption Date, the principal amount of Notes to be redeemed and the Redemption Price. The Company shall give this notice to the Trustee by a Company Order at least thirty (30) calendar days and no more than sixty
(60) calendar days before the Redemption Date. 
 Section 6.02. Selection of Notes To Be Redeemed. The provisions of
Section 1103 of the Base Indenture shall govern the selection of Notes to be redeemed by the Trustee; provided however, that if less than all of the Notes are to be redeemed, the Trustee shall make the selection from the Notes then Outstanding
and not previously called for redemption, by lot, or in its discretion, on a pro rata basis. 
 Section 6.03. Notice of Redemption.
The provisions of Section 1104 of the Base Indenture shall govern notices of redemption; provided, however, that in addition to the information specified by Section 1104 of the Base Indenture, such notices shall also
state: 
 (1) the Conversion Rate; 
 (2) the name and address of the Paying Agent and Conversion Agent; 
 (3) Securities called for redemption may be converted at any
time prior to 5:00 p.m., New York City time, on the Business Day preceding the Redemption Date; 
  

 40 

 (4) that Holders who want to convert their Notes must satisfy the requirements set forth in Article 4;
and 
 (5) that Notes called for redemption must be surrendered to the Paying Agent to collect the Redemption Price. 
 ARTICLE 7 
 EVENTS
OF DEFAULT 
 Section 7.01. Events of Default. Sections 501 and 502 of the Base Indenture shall not
be applicable to the Notes. The following events shall be Events of Default with respect to the Notes: 
 (a) default in any payment of
interest, on any Note when due and payable and the default continues for a period of thirty (30) days; 
 (b) default in the payment of
principal of any Note when due and payable on the Stated Maturity, upon redemption, upon required repurchase, upon declaration or otherwise; 
 (c) failure by the Company to comply with its obligation to convert the Notes into cash or a combination of cash and Common Stock, as applicable, upon exercise of a Holder’s conversion right; 
 (d) failure by the Company to comply with its obligations under Article VIII of the Base Indenture, as amended by Section 3.01 hereof; 

(e) failure by the Company to issue a Company Notice in accordance with Section 5.03(b) when due; 
 (f) failure by the Company for sixty (60) days to comply with any of its other agreements (other than a covenant or warranty or default in whose
performance or whose breach is elsewhere in this Section specifically provided for) contained in the Notes or the Indenture after written notice of such default from the Trustee or the Holders of at least 25% in principal amount of the Notes then
outstanding has been received by the Company; 
 (g) default by the Company or any Subsidiary of the Company in the payment of the principal
or interest on any mortgage, agreement or other instrument under which there may be outstanding, or by which there may be secured or evidenced, any debt for money borrowed in excess of $50 million in the aggregate of the Company and/or any such
Subsidiary, whether such debt now exists or shall hereafter be created, which default results in such debt becoming or being declared due and payable, and such acceleration shall not have been rescinded or annulled within thirty (30) days after
written notice of such acceleration has been received by the Company or such Subsidiary; 
  

 41 

 (h) any final and non-appealable judgment or judgments for the payment of money (net of any amount
covered by insurance) in an aggregate amount in excess of $50 million (or its foreign currency equivalent at the time) that shall be rendered against the Company or any majority-owned subsidiary and that shall not be waived, satisfied or discharged
for any period of sixty (60) consecutive days during which a stay of enforcement shall not be in effect; 
 (i) the Company shall
commence a voluntary case or other proceeding seeking liquidation, reorganization or other relief with respect to the Company or any of its Significant Subsidiaries or its debts under any bankruptcy, insolvency or other similar law now or hereafter
in effect or seeking the appointment of a trustee, receiver, liquidator, custodian or other similar official of the Company or any of its Significant Subsidiaries or any substantial part of its property, or shall consent to any such relief or to the
appointment of or taking possession by any such official in an involuntary case or other proceeding commenced against it, or shall make a general assignment for the benefit of creditors, or shall fail generally to pay its debts as they become due;
or 
 (j) an involuntary case or other proceeding shall be commenced against the Company or any of its Significant Subsidiaries seeking
liquidation, reorganization or other relief with respect to the Company or its debts under any bankruptcy, insolvency or other similar law now or hereafter in effect or seeking the appointment of a trustee, receiver, liquidator, custodian or other
similar official of the Company or any of its Significant Subsidiaries or any substantial part of its property, and such involuntary case or other proceeding shall remain undismissed and unstayed for a period of ninety (90) consecutive days.

 In case one or more Events of Default shall have occurred and be continuing (whatever the reason for such Event of Default and whether it
shall be voluntary or involuntary or be effected by operation of law or pursuant to any judgment, decree or order of any court or any order, rule or regulation of any administrative or governmental body), then, and in each and every such case (other
than an Event of Default specified in Section 7.01(i) or Section 7.01(j) with respect to the Company), unless the principal of all of the Notes shall have already become due and payable, either the Trustee or the Holders of at least 25% in
aggregate principal amount of the Notes then outstanding, by notice in writing to the Company (and to the Trustee if given by Holders), may declare 100% of the principal of, and accrued and unpaid interest on, all the Notes to be due and payable
immediately, and upon any such declaration the same shall become and shall be immediately due and payable, anything in this Indenture or in the Notes contained to the contrary notwithstanding. If an Event of Default specified in Section 7.01(i)
or Section 7.01(j) occurs and is continuing with respect to the Company, the principal of all the Notes and accrued and unpaid interest shall be immediately due and payable. This provision, however, is subject to the conditions that if, at any
time after the principal of the Notes shall have been so declared due and payable, and before any judgment or decree for the payment of the monies due shall have been obtained or entered as hereinafter provided, the 
  

 42 

 Company shall pay or shall deposit with the Trustee a sum sufficient to pay installments of accrued and unpaid interest
upon all Notes and the principal of any and all Notes that shall have become due otherwise than by acceleration (with interest on overdue installments of accrued and unpaid interest (to the extent that payment of such interest is enforceable under
applicable law) and on such principal at the rate borne by the Notes during the period of such Default) and amounts due to the Trustee pursuant to Section 607 of the Base Indenture, and if (1) rescission would not conflict with any
judgment or decree of a court of competent jurisdiction and (2) any and all Events of Defaults under this Indenture, other than the nonpayment of principal of and accrued and unpaid interest on Notes that shall have become due solely by such
acceleration, shall have been cured or waived pursuant to 7.02, then and in every such case the Holders of a majority in aggregate principal amount of the Notes then outstanding, by written notice to the Company and to the Trustee, may waive all
defaults or Events of Default with respect to the Notes and rescind and annul such declaration and its consequences and such default shall cease to exist, and any Event of Default arising therefrom shall be deemed to have been cured for every
purpose of this Indenture; but no such waiver or rescission and annulment shall extend to or shall affect any subsequent default or Event of Default, or shall impair any right consequent thereon. The Company shall notify the Responsible Officer of
the Trustee in writing, promptly upon becoming aware thereof, of any Event of Default by delivering to the Trustee a statement specifying such Event of Default and any action the Company has taken, is taking or proposes to take with respect thereto.

 (k) Notwithstanding the foregoing, if so elected by the Company, the sole remedy for an Event of Default relating to the failure to comply
with Section 3.04 of this Supplemental Indenture, Section 704 of the Base Indenture or Section 314(a)(1) of the Trust Indenture Act, will for the first sixty (60) days after the occurrence of such an Event of Default (the
“Period”) consist exclusively of the right to receive additional interest (the “Reporting Interest”) accruing on the Notes at a rate equal to 0.25% of the principal amount of the Notes for this Period, which
Reporting Interest will stop accruing if such Event of Default is cured prior to the end of the Period. The Reporting Interest will be in addition to any Additional Interest that may accrue pursuant to Section 2.02(b). Such Reporting Interest
will be payable in the same manner as Additional Interest pursuant to Section 2.02(b). The Reporting Interest will accrue on all outstanding Notes from and including the date on which an Event of Default relating to a failure to comply with the
reporting obligations in the Indenture first occurs to, but not including, the sixtieth (60th) day thereafter.
On the sixtieth (60th) day after such Event of Default (if the Event of Default relating to the reporting
obligations is not cured or waived prior to such sixtieth (60th) day), the Reporting Interest will cease to
accrue and the Notes will be subject to acceleration as provided above. The foregoing provisions in this paragraph will not affect the rights of Holders of Notes in the event of the occurrence of any other Event of Default. In the event the Company
does not elect to pay the Reporting Interest upon an Event of Default in accordance with this paragraph, the Notes will be subject to acceleration as provided in the immediately preceding paragraph. 
  

 43 

 (l) In order to elect to pay the Reporting Interest as the sole remedy during the first sixty
(60) days after the occurrence of an Event of Default relating to the failure to comply with the reporting obligations in accordance with the immediately preceding paragraph, the Company must notify all Holders of Notes and the Trustee and
Paying Agent of such election on or before the close of business on the date on which such Event of Default occurs. 
 (m) In case the
Trustee shall have proceeded to enforce any right under this Indenture and such proceedings shall have been discontinued or abandoned because of such waiver or rescission and annulment or for any other reason or shall have been determined adversely
to the Trustee, then and in every such case the Company, the Holders, and the Trustee shall, subject to any determination in such proceeding, be restored respectively to their several positions and rights hereunder, and all rights, remedies and
powers of the Company, the Holders, and the Trustee shall continue as though no such proceeding had been instituted. 
 Section 7.02.
Proceedings by Holders. Section 507 of the Base Indenture shall not be applicable to the Notes. No Holder of any Note shall have any right by virtue of or by availing of any provision of this Indenture to institute any suit, action or
proceeding in equity or at law upon or under or with respect to this Indenture, or for the appointment of a receiver, trustee, liquidator, custodian or other similar official, or for any other remedy hereunder, unless such Holder previously shall
have given to the Trustee written notice of an Event of Default and of the continuance thereof, and unless also the Holders of not less than 25% in aggregate principal amount of the Notes then Outstanding shall have made written request upon the
Trustee to institute such action, suit or proceeding in its own name as Trustee hereunder and shall have offered to the Trustee such security or indemnity reasonably satisfactory to it against any loss, liability or expense to be incurred therein or
thereby, and the Trustee for sixty (60) days after its receipt of such notice, request and offer of indemnity, shall have neglected or refused to institute any such action, suit or proceeding and no direction that, in the opinion of the
Trustee, is inconsistent with such written request shall have been given to the Trustee by the Holders of a majority in principal amount of the Notes outstanding pursuant toSection 7.03; it being understood and intended, and being expressly
covenanted by the taker and Holder of every Note with every other taker and Holder and the Trustee, that no one or more Holders shall have any right in any manner whatever by virtue of or by availing of any provision of this Indenture to affect,
disturb or prejudice the rights of any other Holder, or to obtain or seek to obtain priority over or preference to any other such Holder, or to enforce any right under this Indenture, except in the manner herein provided and for the equal, ratable
and common benefit of all Holders (except as otherwise provided in the Indenture). For the protection and enforcement of this Section 7.02, each and every Holder and the Trustee shall be entitled to such relief as can be given either at law or
in equity. 
  

 44 

 Notwithstanding any other provision of this Indenture and any provision of any Note, the right of any
Holder to receive payment of the principal of and accrued and unpaid interest on such Note, on or after the respective due dates expressed in such Note, or to institute suit for the enforcement of any such payment on or after such respective dates
against the Company shall not be impaired or affected without the consent of such Holder. 
 Anything in this Indenture or the Notes to the
contrary notwithstanding, the Holder of any Note, without the consent of either the Trustee or the Holder of any other Note, in his own behalf and for his own benefit, may enforce, and may institute and maintain any proceeding suitable to enforce,
his rights of conversion as provided herein. 
 Section 7.03. Direction of Proceedings and Waiver of Defaults by Majority of Holders.
Sections 512 and 513 of the Base Indenture shall not be applicable to the Notes. The Holders of a majority in aggregate principal amount of the Notes at the time outstanding shall have the right to direct the time, method, and place of
conducting any proceeding for any remedy available to the Trustee or exercising any trust or power conferred on the Trustee with respect to Notes; provided, however, that (a) such direction shall not be in conflict with any rule
of law or with this Indenture, and (b) the Trustee may take any other action deemed proper by the Trustee that is not inconsistent with such direction. The Trustee may refuse to follow any direction that it determines is unduly prejudicial to
the rights of any other Holder or that would involve the Trustee in personal liability. The Holders of a majority in aggregate principal amount of the Notes at the time outstanding may, on behalf of the Holders of all of the Notes waive any past
default or Event of Default hereunder and its consequences except (i) a Default in the payment of and accrued and unpaid interest on, or the principal of, the Notes when due which has not been cured pursuant to the provisions of
Section 7.01, (ii) a failure by the Company to deliver cash and, if applicable, shares of Common Stock (and cash in lieu of fractional shares) upon conversion of the Notes, or (iii) a Default in respect of a covenant or provisions
hereof which under Article 8 hereof cannot be modified or amended without the consent of each Holder of an outstanding Note affected thereby. Upon any such waiver the Company, the Trustee and the Holders shall be restored to their former positions
and rights hereunder, but no such waiver shall extend to any subsequent or other default or Event of Default or impair any right consequent thereon. Whenever any default or Event of Default hereunder shall have been waived as permitted by this
Section 7.03, said default or Event of Default shall for all purposes of the Notes and this Indenture be deemed to have been cured and to be not continuing; but no such waiver shall extend to any subsequent or other Default or Event of Default
or impair any right consequent thereon. 
 Section 7.04. Notice of Defaults. Section 602 of the Base Indenture shall not be
applicable to the Notes. The Trustee shall, within ninety (90) days after the occurrence and continuance of a Default of which a Responsible Officer has actual knowledge, mail to all Holders as the names and addresses of such Holders

  

 45 

 appear upon the Security Register, notice of all Defaults known to a Responsible Officer, unless such Defaults shall have
been cured or waived before the giving of such notice; and provided that, except in the case of a Default in the payment of the principal of and accrued and unpaid interest on any of the Notes, then in any such event the Trustee shall be protected
in withholding such notice if and so long as a committee of trust officers of the Trustee in good faith determine that the withholding of such notice is in the interests of the Holders. 
 Section 7.05. Statement by Officers as to Default. Section 1005 of the Base Indenture shall not be applicable to the Notes. The Company
shall deliver to the Trustee within 120 calendar days after the end of each fiscal year of the Company (beginning with the fiscal year ending on December 31, 2006) an Officer’s Certificate stating whether or not the signer thereof has
knowledge of any failure by the Company to comply with all conditions and covenants then required to be performed under this Indenture and, if so, specifying each such failure and the nature thereof. 
 In addition, the Company shall deliver to the Trustee, as soon as possible and in any event within thirty (30) days after the Company becomes aware
of the occurrence of any Event of Default or Default, an Officer’s Certificate setting forth the details of such Event of Default or Default, its status and the action which the Company proposes to take with respect thereto. 
 ARTICLE 8 
 SUPPLEMENTAL
INDENTURES 
 Section 8.01. Supplemental Indentures without the Consent of Holders. The provisions of
Section 901 of the Base Indenture shall not be applicable to the Notes. With respect to the Notes, without the consent of any Holders, the Company, when authorized by a Board Resolution, any Security Guarantor and the Trustee, at any time and
from time to time, may enter into one or more indentures supplemental hereto, in form reasonably satisfactory to the Trustee, for any of the following purposes: 
 (a) to cure any ambiguity, omission, defect or inconsistency; 
 (b) to provide for the assumption by a
Successor Company of the obligations of the Company under the Indenture pursuant to Article VIII of the Base Indenture; 
 (c) to provide for
uncertificated Notes in addition to or in place of certificated Notes (provided that the uncertificated Notes are issued in registered form for purposes of Section 163(f) of the Code, or in a manner such that the uncertificated Notes are
described in Section 163(f)(2)(B) of the Code); 
 (d) to add guarantees with respect to the Notes; 
  

 46 

 (e) to secure the Notes; 
 (f) to add to the covenants of the Company for the benefit of the Holders or surrender any right or power conferred upon the Company; 
 (g) to make any change that does not materially adversely affect the rights of any Holder; 
 (h) to comply
with any requirements of the Commission in connection with the qualification of the Indenture under the Trust Indenture Act; or 
 (i) to
conform any provision contained in the Indenture to the section of the Offering Memorandum, dated as of December 11, 2006, related to the offering of the Notes, captioned “Description of Notes.” 
 Section 8.02. Supplemental Indentures with the Consent of Holders. The provisions of Section 901 of the Base Indenture shall not be
applicable to the Notes. With respect to the Notes, with the consent of the Holders of not less than a majority in principal amount of the Outstanding Notes affected by such supplemental indenture (voting as one class), by Act of said Holders
delivered to the Company and the Trustee, the Company, when authorized by a Board Resolution, the Security Guarantors and the Trustee may enter into an indenture or indentures supplemental hereto for the purpose of adding any provisions to or
changing in any manner or eliminating any of the provisions of this Indenture or of any supplemental indenture, or modifying in any manner the rights of the Holders; provided, however, that no such supplemental indenture shall, without
the consent of the Holder of each Outstanding Note affected thereby: 
 (a) reduce the percentage in aggregate principal amount of Notes the
Holders of which must consent to an amendment; 
 (b) reduce the rate, or extend the stated time for payment, of interest on any Note;

 (c) reduce the principal, or extend the Stated Maturity, of any Note; 
 (d) make any change that adversely affects the conversion rights of any Notes; 
 (e) reduce the Purchase Price or Designated Event Repurchase Price of any Note or amend or modify in any manner adverse to the Holders of the Notes the
Company’s obligation to make such payments, whether through an amendment or waiver of provisions in the covenants, definitions or otherwise; 
 (f) change the place or currency of payment of principal or interest in respect of any Note; 
  

 47 

 (g) impair the right of any Holder to receive payment of principal of, and interest on, such
Holder’s Notes on or after the due dates therefor or to institute suit for the enforcement of any payment on or with respect to such Holder’s Note; or 
 (h) make any change in the provisions of this Article 8 or Article IX of the Base Indenture that require each Holder’s consent or in the waiver provisions in Section 7.01 and Section 7.03. 

ARTICLE 9 
 TAX
TREATMENT 
 Section 9.01. Tax Treatment. The parties hereto hereby agree, and each Holder and any beneficial
holder of a Note by its purchase of a Note hereby agrees (in the absence of administrative pronouncement or judicial ruling to the contrary): 
 (a) to treat the Notes as indebtedness of the Company for all United States federal income tax purposes; 
 (b) to treat the Notes
as debt instruments that are subject to Treasury Regulation section 1.1275-4(b); 
 (c) to treat the delivery of Common Stock or cash
(including cash delivered in lieu of a fractional share) to a Holder of a Note upon conversion of such Note, or upon a repurchase or redemption of such Note by the Company, as a contingent payment (in an amount equal to the sum of the Fair Market
Value of such Common Stock and any cash received) under Treasury Regulation section 1.1275-4(b); and 
 (d) to be bound by the Company’s
application of Treasury Regulation section 1.1275-4(b), including the Company’s determination of the comparable yield and the projected payment schedule attached as Annex 1 to this Indenture. 
 Section 9.02. Comparable Yield And Projected Payment Schedule. 
 (a) Solely for purposes of applying Treasury Regulation section 1.1275-4 to the Notes: 
 (i)
for United States federal income tax purposes, the Company shall accrue interest with respect to outstanding Notes as original issue discount according to the “noncontingent bond method,” as set forth in Treasury Regulation section
1.1275-4(b) using a comparable yield of 5.59%, compounded semiannually, and the projected payment schedule attached as Annex 1 to this Indenture; and 
  

 48 

 (ii) the Company shall file with the Trustee promptly at the end of each calendar year
(A) a written notice specifying the amount of original issue discount for United States federal income tax purposes accrued on outstanding Notes as of the end of such year and (B) such other specific information relating to such original
issue discount that the Company determines to be relevant under the Internal Revenue Code of 1986, as amended from time to time, including the amount of any adjustment made under the noncontingent bond method to account for the amount of any
difference between the amount of an actual payment and the amount of a projected payment. 
 ARTICLE 10 
 MISCELLANEOUS 
 Section 10.01. Governing Law. This Supplemental Indenture shall be deemed to be a contract under the laws of the State of New York, and for all purposes shall be construed in accordance with the laws of such State. 

Section 10.02. Confirmation of Indenture. The Base Indenture, as supplemented and amended by this Supplemental Indenture, is in all
respects ratified and confirmed, and the Base Indenture and this Supplemental Indenture shall be read, taken and construed as one and the same instrument.  
  

 49 

 IN WITNESS WHEREOF, the parties hereto have caused this Supplemental Indenture to be duly executed, and
their respective corporate seals to be hereunto affixed and attested, all as of the first date written above. 
  

			
	BECKMAN COULTER, INC.
		
	By:	 	 /s/Arnold Pinkston

	Name:	 	Arnold Pinkston
	Title:	 	Senior Vice President and General Counsel

  

			
	Attest:
		
	By:	 	 /s/ Jack E. Sorokin

	Name:	 	Jack E. Sorokin
	Title:	 	Deputy General Counsel

  

			
	 WELLS FARGO BANK, NATIONAL ASSOCIATION,
     as Trustee

		
	By:	 	 /s/ Maddy Hall

	Name:	 	Maddy Hall
	Title:	 	Assistant Vice President

  

			
	Attest:
		
	By:	 	 /s/ Scott C. Emmons

	Name:	 	Scott C. Emmons
	Title:	 	Vice President

 SCHEDULE A 
  

																											
	 Stock
Price

														
	 Effective Date
	  	$59.37	  	$60.00	  	$65.00	  	$70.00	  	$75.00	  	$80.00	  	$90.00	  	$100.00	  	$120.00	  	$140.00	  	$160.00	  	$180.00	  	$200.00
	 12/11/2006
	  	3.3687	  	3.2825	  	2.7023	  	2.2559	  	1.9085	  	1.6354	  	1.2437	  	0.9854	  	0.6790	  	0.5086	  	0.3999	  	0.3234	  	0.2657
	 12/15/2007
	  	3.3687	  	3.2604	  	2.6478	  	2.1804	  	1.8204	  	1.5406	  	1.1470	  	0.8946	  	0.6062	  	0.4522	  	0.3561	  	0.2889	  	0.2383
	 12/15/2008
	  	3.3687	  	3.1935	  	2.5492	  	2.0626	  	1.6927	  	1.4096	  	1.0209	  	0.7806	  	0.5190	  	0.3862	  	0.3052	  	0.2487	  	0.2061
	 12/15/2009
	  	3.3687	  	3.1195	  	2.4349	  	1.9244	  	1.5424	  	1.2558	  	0.8751	  	0.6512	  	0.4234	  	0.3152	  	0.2507	  	0.2056	  	0.1712
	 12/15/2010
	  	3.3687	  	3.0497	  	2.3091	  	1.7647	  	1.3662	  	1.0752	  	0.7066	  	0.5057	  	0.3208	  	0.2406	  	0.1934	  	0.1599	  	0.1339
	 12/15/2011
	  	3.3687	  	2.9876	  	2.1632	  	1.5680	  	1.1457	  	0.8504	  	0.5051	  	0.3405	  	0.2127	  	0.1633	  	0.1334	  	0.1112	  	0.0937
	 12/15/2012
	  	3.3687	  	2.9593	  	1.9862	  	1.2975	  	0.8355	  	0.5412	  	0.2556	  	0.1582	  	0.1051	  	0.0846	  	0.0701	  	0.0589	  	0.0500
	 12/15/2013
	  	3.3687	  	3.1919	  	1.9098	  	0.8109	  	0.0000	  	0.0000	  	0.0000	  	0.0000	  	0.0000	  	0.0000	  	0.0000	  	0.0000	  	0.0000

 EXHIBIT A 
 THIS NOTE HAS BEEN ISSUED WITH ORIGINAL ISSUE DISCOUNT, FOR PURPOSES OF SECTIONS 1272, 1273 AND 1275 OF THE INTERNAL REVENUE CODE OF 1986, AS AMENDED. THE ISSUE PRICE OF THIS NOTE IS $1,000 PER $1,000 OF PRINCIPAL AMOUNT AT MATURITY; THE
ISSUE DATE OF THIS NOTE IS DECEMBER 15, 2006; AND THE COMPARABLE YIELD FOR THE PURPOSES OF ACCRUING ORIGINAL ISSUE DISCOUNT IS 5.59% PER ANNUM, CALCULATED ON A SEMIANNUAL BOND EQUIVALENT BASIS. HOLDERS OF THIS NOTE MAY OBTAIN INFORMATION
REGARDING THE AMOUNT OF ORIGINAL ISSUE DISCOUNT, YIELD TO MATURITY AND THE PROJECTED PAYMENT SCHEDULE FOR THIS NOTE BY SUBMITTING A WRITTEN REQUEST FOR SUCH INFORMATION TO: VICE PRESIDENT, TAXATION, P.O. BOX 3100, FULLERTON, CA 92834-3100.

 [THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF A DEPOSITARY OR A NOMINEE
THEREOF. THIS SECURITY MAY NOT BE EXCHANGED IN WHOLE OR IN PART FOR A SECURITY REGISTERED, AND NO TRANSFER OF THIS SECURITY IN WHOLE OR IN PART MAY BE REGISTERED, IN THE NAME OF ANY PERSON OTHER THAN SUCH DEPOSITARY OR A NOMINEE THEREOF, EXCEPT IN
THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE.]1 
 [THIS NOTE (OR ITS PREDECESSOR) WAS ORIGINALLY ISSUED IN A TRANSACTION EXEMPT FROM REGISTRATION UNDER THE UNITED STATES SECURITIES ACT OF 1933 (THE “SECURITIES
ACT”), AND THIS NOTE AND THE COMMON STOCK ISSUABLE UPON CONVERSION HEREOF MAY NOT BE OFFERED, SOLD OR OTHERWISE TRANSFERRED IN THE ABSENCE OF SUCH REGISTRATION OR AN APPLICABLE EXEMPTION THEREFROM. EACH PURCHASER OF THIS NOTE IS HEREBY NOTIFIED
THAT THE SELLER OF THIS NOTE MAY BE RELYING ON THE EXEMPTION FROM THE PROVISIONS OF SECTION 5 OF THE SECURITIES ACT PROVIDED BY RULE 144A THEREUNDER. THE HOLDER OF THIS NOTE AGREES FOR THE BENEFIT OF BECKMAN COULTER, INC., THAT (A) THIS NOTE
AND THE COMMON STOCK ISSUABLE UPON CONVERSION HEREOF MAY BE OFFERED, RESOLD, PLEDGED OR OTHERWISE TRANSFERRED, ONLY (I) TO BECKMAN COULTER, INC. OR ANY SUBSIDIARY THEREOF, (II) IN THE UNITED 
  

	1	Include this Legend on a Global Security only. 

 Exhibit A-1 

 STATES TO A PERSON WHOM THE SELLER REASONABLY BELIEVES IS A QUALIFIED INSTITUTIONAL BUYER (AS DEFINED IN RULE 144A UNDER
THE SECURITIES ACT) IN A TRANSACTION MEETING THE REQUIREMENTS OF RULE 144A, (III) INSIDE THE UNITED STATES TO AN INSTITUTIONAL ACCREDITED INVESTOR THAT, BEFORE SUCH TRANSFER, FURNISHES TO WELLS FARGO BANK, NATIONAL ASSOCIATION, AS TRUSTEE (OR A
SUCCESSOR TRUSTEE, AS APPLICABLE), A SIGNED LETTER CONTAINING CERTAIN REPRESENTATIONS AND AGREEMENTS RELATING TO THE RESTRICTIONS ON TRANSFER OF THE NOTES (THE FORM OF WHICH LETTER CAN BE OBTAINED FROM SUCH TRUSTEE OR A SUCCESSOR TRUSTEE, AS
APPLICABLE), (IV) OUTSIDE THE UNITED STATES IN AN OFFSHORE TRANSACTION IN ACCORDANCE WITH RULE 904 UNDER THE SECURITIES ACT, (V) PURSUANT TO AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT PROVIDED BY RULE 144 THEREUNDER (IF AVAILABLE)
OR (VI) PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT, IN EACH OF CASES (I) THROUGH (VI) IN ACCORDANCE WITH ANY APPLICABLE SECURITIES LAWS OF ANY STATE OF THE UNITED STATES, AND (B) THE HOLDER WILL, AND EACH
SUBSEQUENT HOLDER IS REQUIRED TO, NOTIFY ANY PURCHASER OF THIS NOTE FROM IT OF THE RESALE RESTRICTIONS REFERRED TO IN (A) ABOVE. IN ANY CASE, THE HOLDER HEREOF WILL NOT, DIRECTLY OR INDIRECTLY, ENGAGE IN ANY HEDGING TRANSACTIONS WITH REGARD TO
THE SECURITIES EXCEPT AS PERMITTED UNDER THE SECURITIES ACT.]2 
 BECKMAN COULTER, INC. 
 2.50% Senior Convertible Notes due 2036 
  

				
		  	$	                      
	 No.     
	  	 	CUSIP No.:     
		  	 	ISN No.:     

 Beckman Coulter, Inc., a corporation duly organized and existing under the laws of the State of
Delaware (herein called the “Company,” which term includes any successor Person under the Indenture hereinafter referred to), for value received, hereby promises to pay to [CEDE & CO]3, or registered
assigns, the principal sum of $             (             Million Dollars) on December 15, 2036, and to pay
interest thereon from December 15, 2006 or from the most recent Interest Payment Date to which interest has been paid or duly provided for, semi-annually on June 15 and December 15 in each year, commencing June 15, 2007,

  

	2	Include this Legend on a Restricted Global Note only. 

	3	Include on a Global Security only. 

 Exhibit A-2 

 at the rate of 2.50% per annum, until the principal hereof is paid or made available for payment. The interest so
payable, and punctually paid or duly provided for, on any Interest Payment Date will, as provided in such Indenture, be paid to the Person in whose name this Note (or one or more Predecessor Notes) is registered at the close of business on the
Regular Record Date for such interest, which shall be the June 1 and December 1 (whether or not a Business Day), as the case may be, next preceding such Interest Payment Date. Any such interest not so punctually paid or duly provided for
will forthwith cease to be payable to the Holder on such Regular Record Date and may either be paid to the Person in whose name this Security (or one or more Predecessor Notes) is registered at the close of business on a Special Record Date for the
payment of such Defaulted Interest to be fixed by the Trustee, notice whereof shall be given to Holders of Notes not less than ten (10) days prior to such Special Record Date, or be paid at any time in any other lawful manner not inconsistent
with the requirements of any securities exchange on which the Notes may be listed, and upon such notice as may be required by such exchange, all as more fully provided in said Indenture. 
 Payment of the principal of (and premium, if any) and any such interest on this Note will be made at the office or agency of the Company maintained for
that purpose in New York, New York, in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private debts. 
 Reference is hereby made to the further provisions of Note set forth on the reverse hereof, which further provisions shall for all purposes have the same
effect as if set forth at this place. 
 Unless the certificate of authentication hereon has been executed by the Trustee referred to on the
reverse hereof by manual signature, this Note shall not be entitled to any benefit under the Indenture or be valid or obligatory for any purpose. 
 [Remainder of page intentionally left blank] 
 Exhibit A-3 

 IN WITNESS WHEREOF, the Company has caused this Security to be signed manually or by facsimile by its
duly authorized officer under its corporate seal. 
  

			
	BECKMAN COULTER, INC.
		
	By:	 	  

	Name:	 	
	Title:	 	

  

			
	Attest:
		
	By:	 	  

	Name:	 	
	Title:	 	

 Exhibit A-4 

 CERTIFICATE OF AUTHENTICATION 
 This is one of the series designated herein and referred to in the within-mentioned Indenture. 
 Dated: December     , 2006 
  

			
	 WELLS FARGO BANK, NATIONAL ASSOCIATION,
     as Trustee

		
	By:	 	  

		 	Authorized Signatory

  

			
	Attest:
		
	By:	 	  

		 	Authorized Signatory

 Exhibit A-5 

 (REVERSE OF NOTE) 
 BECKMAN COULTER, INC. 
 2.50 % Note Due 2036 
 1. Indenture. 
 This Security is one of a
duly authorized issue of securities of the Company (herein called the “Notes”), issued and to be issued in one or more series under the Senior Indenture dated as of April 25, 2001 (as amended, modified or supplemented from time
to time in accordance therewith, the “Base Indenture” and, as amended, modified and supplemented by the Second Supplemental Indenture dated as of December 15, 2006, the “Indenture”), between the Company and
Wells Fargo Bank, National Association (herein called the “Trustee” which term includes any successor trustee under the Indenture), and reference is hereby made to the Indenture for a statement of the respective rights, limitation
of rights, duties and immunities thereunder of the Company, the Trustee and the Holders of the Notes and of the terms upon which the Securities are, and are to be, authenticated and delivered. This Security is one of the series designated on the
face hereof limited in aggregate principal amount to $600,000,000. 
 2. Interest. 
 BECKMAN COULTER, INC., a Delaware corporation (the “Company”), promises to pay interest on the principal amount of this Note at the rate
per annum shown above plus [Additional Interest as provided in the Registration Rights Agreement]4[,] Reporting Interest and Contingent Interest, if any. Cash interest on the Notes will accrue from the most recent date to
which interest has been paid or, if no interest has been paid, from December 15, 2006. The Company will pay interest semiannually in arrears on each Interest Payment Date, commencing June 15, 2007. Interest will be computed on the basis of
a 360-day year of twelve 30-day months. 
 No reference herein to the Indenture and no provision of this Note or of the Indenture shall alter
or impair the obligation of the Company, which is absolute and unconditional, to pay the principal of and any premium and interest on this Note at the times, place and rate, and in the coin or currency, herein prescribed. 
  

	4	Insert in Restricted Security only. 

 Exhibit A-6 

 3. Paying Agent and Conversion Agent. 
 Initially, the Trustee will act as Paying Agent and Conversion Agent. The Company may change any Paying Agent or Conversion Agent without notice to the
Holders. 
 4. Conversion. 
 Subject to the provisions of the Indenture, the Holder hereof has the right, at its option, on and after December 15, 2013, or earlier upon the occurrence of certain conditions specified in the Indenture and prior to the close of
business on the Trading Day immediately preceding the Stated Maturity, to convert any Notes or portion thereof which is $1,000 or a multiple thereof, into cash and, if applicable, shares of Common Stock, in each case at the Conversion Rate specified
in the Indenture, as adjusted from time to time as provided in the Indenture, upon surrender of this Note, together with a Notice of Conversion, a form of which is attached to the Note, as provided in the Indenture and this Note, to the Company at
the office or agency of the Company maintained for that purpose in the Borough of Manhattan, The City of New York, or at the option of such Holder, the Corporate Trust Office, and, unless the shares issuable on conversion are to be issued in the
same name as this Note, duly endorsed by, or accompanied by instruments of transfer in form satisfactory to the Company duly executed by, the Holder or by his duly authorized attorney. The initial Conversion Rate shall be 13.4748 shares for each
$1,000 principal amount of Notes. No fractional shares of Common Stock will be issued upon any conversion, but an adjustment in cash will be paid to the Holder, as provided in the Indenture, in respect of any fraction of a share which would
otherwise be issuable upon the surrender of any Note or Notes for conversion. No adjustment shall be made for dividends or any shares issued upon conversion of such Note except as provided in the Indenture. 
 5. Purchase by the Company at the Option of the Holder. 
 On Specified Dates and upon the occurrence of a Designated Event, the Holder has the right, at such Holder’s option, to require the Company to repurchase all of such Holder’s Notes or any portion thereof (in
principal amounts of $1,000 or multiples thereof) on the Specified Purchase Date or Designated Event Repurchase Date, as the case may be, at a price equal to 100% of the principal amount of the Notes such Holder elects to require the Company to
repurchase, together with accrued and unpaid interest, including [Additional Interest][,] Reporting Interest and Contingent Interest, if any, to but excluding the Specified Purchase Date or Designated Event Repurchase Date, as the case may be. The
Company or, at the written request of the Company, the Trustee shall mail to all Holders of record of the Notes a notice of the occurrence of a Designated Event and of the repurchase right arising as a result thereof on or before the tenth
(10th) day after the occurrence of any Designated Event. 
 Exhibit A-7 

 6. Redemption. 
 The Company may, at its option, redeem the Notes for cash at any time as a whole, or from time to time in part, on or after December 20, 2013, at a redemption price equal to 100% of the principal amount of Notes
to be redeemed plus any accrued and unpaid interest, including [Additional Interest][,] Reporting Interest and Contingent Interest, if any, on those Notes to, but not including, the Redemption Date. 
 Notice of redemption pursuant to this Section of this Note will be mailed at least thirty (30) days but not more than sixty (60) days before
the Redemption Date to each Holder of Securities to be redeemed at the Holder’s registered address. If cash sufficient to pay the Redemption Price of all Notes (or portions thereof) to be redeemed on the Redemption Date is deposited with the
Paying Agent prior to 10:00 a.m., New York City time, on the Redemption Date, then on such Redemption Date interest, including [Additional Interest][,] Reporting Interest and Contingent Interest, if any, cease to accrue on such Notes or portions
thereof. Notes in denominations larger than $1,000 of principal amount may be redeemed in part but only in multiples of $1,000 of principal amount. 
 The Notes are not subject to redemption through the operation of any sinking fund. 
 7. Denominations; Transfer; Exchange.

 The Notes are issuable only in registered form without coupons in denominations of $1,000 and multiples thereof. As provided in the
Indenture and subject to certain limitations therein set forth, the Notes are exchangeable for a like aggregate principal amount of Notes and of like tenor of a different authorized denomination, as requested by the Holder surrendering the same.

 As provided in the Indenture and subject to certain limitations therein set forth, the transfer of this Note is registrable in the
Security Register, upon surrender of this Note for registration of transfer at the office or agency of the Company in any place where the principal of and any premium and interest on this Note are payable, duly endorsed by, or accompanied by a
written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed by, the Holder hereof or his attorney duly authorized in writing, and thereupon one or more new Notes and of like tenor, of authorized
denominations and for the same aggregate principal amount, will be issued to the designated transferee or transferees. 
 No service charge
shall be made for any such registration of transfer or exchange, but the Company may require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 
 Exhibit A-8 

 8. Persons Deemed Owners. 
 Prior to due presentment of this Note for registration of transfer, the Company, the Trustee and any agent of the Company or the Trustee may treat the Person in whose name this Note is registered as the owner hereof
for all purposes, whether or not this Note be overdue, and neither the Company, the Trustee nor any such agent shall be affected by notice to the contrary. 
 9. Amendment; Supplement; Waiver. 
 The Indenture contains provisions permitting the Company and the Trustee
in certain circumstances, without the consent of the Holders, and in other circumstances, with the consent of the Holders of not less than a majority in aggregate principal amount of the Notes at the time outstanding, evidenced as in the Indenture
provided, to execute supplemental indentures adding any provisions to or changing in any manner or eliminating any of the provisions of the Indenture or of any supplemental indenture or modifying in any manner the rights of the Holders;
provided, however, that no such supplemental indenture shall make any of the changes set forth in Section 8.02 of the Supplemental Indenture, without the consent of each Holder of an outstanding Note affected thereby. It is also
provided in the Indenture that, prior to any declaration accelerating the maturity of the Notes, the Holders of a majority in aggregate principal amount of the Notes at the time outstanding may on behalf of the Holders of all of the Notes waive any
past default or Event of Default under the Indenture and its consequences except as provided in the Indenture. Any such consent or waiver by the Holder of this Note (unless revoked as provided in the Indenture) shall be conclusive and binding upon
such Holder and upon all future Holders and owners of this Note and any Notes which may be issued in exchange or substitution hereof, irrespective of whether or not any notation thereof is made upon this Note or such other Notes. 
 10. Defaults and Remedies. 
 In case an Event
of Default, as defined in the Indenture, shall have occurred and be continuing, the principal of, and accrued and unpaid interest on, all Notes, may be declared, and upon said declaration shall become, due and payable, in the manner, with the effect
and subject to the conditions provided in the Indenture. 
 11. Authentication. 
 This Note shall not be valid until the Trustee manually signs the certificate of authentication on this Note. 
 Exhibit A-9 

 12. Abbreviations and Defined Terms. 
 Customary abbreviations may be used in the name of a Holder of a Note or an assignee, such as: TEN COM (= tenants in common), TEN ENT (= tenants by the
entireties), JT TEN (= joint tenants with right of survivorship and not as tenants in common), CUST (= Custodian), and U/G/M/A (= Uniform Gifts to Minors Act). 
 13. CUSIP Numbers. 
 Pursuant to a recommendation promulgated by the Committee on Uniform Security
Identification Procedures, the Company has caused CUSIP numbers to be printed on the Securities as a convenience to the Holders of the Securities. No representation is made as to the accuracy of such numbers as printed on the Securities and reliance
may be placed only on the other identification numbers printed hereon. 
 14. Governing Law. 
 The Indenture and the Notes issued thereby shall be governed by and construed in accordance with the laws of the State of New York. 
 15. Definitions 
 All terms used in this Note
which are defined in the Indenture shall have the meanings assigned to them in the Indenture. 
 Exhibit A-10 

 [FORM OF NOTICE OF CONVERSION] 
 To: Beckman Coulter, Inc. 
 The undersigned registered owner of this Note hereby exercises the option to
convert this Note, or the portion hereof (that is $1,000 principal amount or a multiple thereof) below designated, into cash and shares of Common Stock, if any, in accordance with the terms of the Indenture referred to in this Note, and directs that
the cash and shares, if any, issuable and deliverable upon such conversion and any Notes representing any unconverted principal amount hereof, be issued and delivered to the registered Holder hereof unless a different name has been indicated below.
If shares or any portion of this Note not converted are to be issued in the name of a Person other than the undersigned, the undersigned will pay all transfer taxes payable with respect thereto. Any amount required to be paid to the undersigned on
account of interest accompanies this Note. 
  

					
	Dated:                     	 		 	  

			
		 		 	  

		 		 	Signature(s)
			
	  
	 		 	
	Signature Guarantee	 		 	
			
		 		 	Signature(s) must be guaranteed by an eligible Guarantor Institution (banks, stock brokers, savings and loan associations and credit unions) with membership in an approved signature guarantee
medallion program pursuant to Securities and Exchange Commission Rule 17Ad 15 if shares of Common Stock are to be issued, or Notes to be delivered, other than to and in the name of the registered Holder.

  

 Exhibit A-11 

	
	Fill in for registration of shares if to be issued, and Notes if to be delivered, other than to and in the name of the registered Holder:
	
	  

	(Name)
	
	  

	(Street Address)
	
	  

	(City, State and Zip Code)
	Please print name and address

  

			
		  	Principal amount to be converted (if less than all):
$                    ,000
		
		  	NOTICE: The above signature(s) of the Holder(s) hereof must correspond with the name as written upon the face of the Note in every particular without alteration or enlargement or any change
whatever.
		
		  	  

		  	Social Security or Other Taxpayer Identification Number

  

 Exhibit A-12 

 [FORM OF REPURCHASE NOTICE] 
 To: Beckman Coulter, Inc. 
 The undersigned registered owner of this Note acknowledges receipt of a notice
from Beckman Coulter, Inc. (the “Company”) as to [a Specified Purchase Date] [the occurrence of a Designated Event] with respect to the Company and requests and instructs the Company to repay the entire principal amount of this
Note, or the portion thereof (that is $1,000 principal amount or a multiple thereof) below designated, in accordance with the applicable provisions of the Indenture referred to in this Note, together with accrued and unpaid interest, including
[Additional Interest][,] Reporting Interest and Contingent Interest, if any, to, but excluding, such date, to the registered Holder hereof. 
 In the case of certificated Notes, the certificate numbers of the Notes to be repurchased are as set forth below. 
  

			
	Dated:                     	 	  

		
		 	  

		 	Signature(s)
		
		 	Principal amount to be converted (if less than all):
$                    ,000
		
		 	NOTICE: The above signature(s) of the Holder(s) hereof must correspond with the name as written upon the face of the Note in every particular without alteration or enlargement or any change
whatever.
		
		 	  

		 	Social Security or Other Taxpayer Identification Number

  

 Exhibit A-13 

 EXHIBIT B 
 [FORM OF ASSIGNMENT AND TRANSFER] 
 For value received
                                        
                                        
             hereby sell(s), assign(s) and transfer(s) unto
                                        
                                        
                 (please insert Social Security or Taxpayer Identification Number of assignee) the within Note, and hereby irrevocably constitutes and appoints
                                        
                                        
                 attorney to transfer the said Note on the books of Beckman Coulter, Inc. (the “Company”), with full power of substitution in the
premises. 
 In connection with any transfer of the within Note occurring prior to the expiration of the holding period applicable to sales thereof under
Rule 144(k) of the Securities Act of 1933, as amended (the “Securities Act”) (or any successor provision thereto), the undersigned confirms that such Note is being transferred: 
  

	 ̈	To Beckman Coulter, Inc. or a Subsidiary thereof; or 

  

	 ̈	Pursuant to the registration statement that has become or been declared effective under the Securities Act of 1933; or 

  

	 ̈	Pursuant to and in compliance with Rule 144A under the Securities Act; or 

  

	 ̈	Pursuant to and in compliance with Rule 144 under the Securities Act; or 

  

	 ̈	Pursuant to another available exemption from registration under the Securities Act. 

  

 Exhibit B-1 

 Dated:
                             
  

	
	  

	
	  

	Signature(s)
	
	  

	Signature Guarantee
	
	Signature(s) must be guaranteed by an eligible Guarantor Institution (banks, stock brokers, savings and loan associations and credit unions) with membership in an approved signature guarantee
medallion program pursuant to Securities and Exchange Commission Rule 17Ad 15 if Notes to be delivered, other than to and in the name of the registered Holder.
	
	NOTICE: The signature on the assignment must correspond with the name as written upon the face of the Note in every particular without alteration or enlargement or any change
whatever.
	
	  

	Social Security or
	Other Taxpayer Identification Number

  

 Exhibit B-2Registration Rights Agreement

 EXHIBIT 4.2 
 REGISTRATION RIGHTS AGREEMENT 
 dated as of December 15, 2006 
 between 
 BECKMAN COULTER, INC.

 and 
 MORGAN
STANLEY & CO. INCORPORATED, 
 as representative of the Initial Purchasers 

 REGISTRATION RIGHTS AGREEMENT dated as of December 15, 2006 between Beckman Coulter, Inc., a
Delaware corporation (the “Company”), and Morgan Stanley & Co. Incorporated, as representative of the several initial purchasers listed on Schedule I (the “Initial Purchasers”) to the Purchase
Agreement dated as of December 11, 2006 (the “Purchase Agreement”) with the Company. In order to induce the Initial Purchasers to enter into the Purchase Agreement, the Company has agreed to provide the registration rights set
forth in this Agreement. The execution of this Agreement is a condition to the closing under the Purchase Agreement. 
 The Company agrees
with the Initial Purchasers, (i) for their benefit as Initial Purchasers and (ii) for the benefit of the owners (including the Initial Purchasers) from time to time of the Securities (as defined herein) and the owners from time to time of
the Underlying Common Stock (as defined herein) issued upon conversion of the Securities (each of the foregoing a “Holder” and together the “Holders”), as follows: 
 Section 1. Definitions. Capitalized terms used herein without definition shall have their respective meanings set forth in the Purchase
Agreement. As used in this Agreement, the following terms shall have the following meanings: 
 “Additional Filing Deadline”
has the meaning set forth in Section 2(f)(v) hereof. 
 “Additional Interest” has the meaning set forth in
Section 2(f) hereof. 
 “Affiliate” means with respect to any specified person, an “affiliate,” as defined in
Rule 144, of such person. 
 “Amendment Effectiveness Deadline” has the meaning set forth in Section 2(e) hereof.

 “Automatic Shelf Registration Statement” has the meaning ascribed to it in Rule 405. 
 “Base Indenture” means the Senior Indenture, dated as of April 25, 2001, between the Company and the Trustee. 
 “Business Day” means any day, except a Saturday, Sunday or legal holiday on which banking institutions in The City of New York are
authorized or obligated by law or executive order to close. 
 “Common Stock” means the shares of common stock, par value
$0.10 per share, of the Company, and any other shares of common stock as may constitute “Common Stock” for purposes of the Indenture, including the Underlying Common Stock. 

 “Conversion Price” has the meaning assigned such term in the Indenture. 
 “Deferral Notice” has the meaning set forth in Section 3(h) hereof. 
 “Deferral Period” has the meaning set forth in Section 3(h) hereof. 
 “Effectiveness Deadline” has the meaning set forth in Section 2(a) hereof. 
 “Effectiveness Period” means the period commencing on the first date that a Shelf Registration Statement is declared effective under the
Securities Act hereof and ending on the date that all Securities and the Underlying Common Stock have ceased to be Registrable Securities. 
 “Exchange Act” means the Securities Exchange Act of 1934, as amended, and the rules and regulations of the SEC promulgated thereunder. 
 “Free Writing Prospectus” has the meaning set forth in Rule 405. 
 “Filing
Deadline” has the meaning set forth in Section 2(a) hereof. 
 “Holder” has the meaning set forth in the
second paragraph of this Agreement. 
 “Indenture” means the Base Indenture, as supplemented, modified and amended by the
Supplemental Indenture. 
 “Initial Purchasers” means the Initial Purchasers named in Schedule I to the Purchase Agreement.

 “Interest Payment Date” means each December 15 and June 15 of each year. 
 “Issue Date” means the first date of original issuance of the Securities. 
 “Issuer Free Writing Prospectus” has the meaning set forth in Rule 433. 
 “Material Event” has the meaning set forth in Section 3(h) hereof. 
 “Notice and Questionnaire” means a written notice delivered to the Company containing substantially the information called for by the
Selling Securityholder Notice and Questionnaire attached as Annex A to the Offering Memorandum of the Company dated as of December 11, 2006 relating to the Securities. 
 “Notice Holder” means, on any date, any Holder that has delivered a Notice and Questionnaire to the Company on or prior to such date.

 “Purchase Agreement” has the meaning set forth in the preamble hereof. 
  

 2 

 “Prospectus” means a prospectus relating to a Shelf Registration Statement, as amended
or supplemented, and all materials incorporated by reference in such Prospectus. 
 “Record Holder” means with respect to
any Interest Payment Date relating to any Securities or Underlying Common Stock as to which any Additional Interest has accrued, the registered holder of such Security on the fifteenth day immediately preceding the Interest Payment Date. 

“Registrable Securities” means the Securities until such Securities have been converted into or exchanged for the Underlying Common
Stock and, at all times subsequent to any such conversion, the Underlying Common Stock and any securities into or for which such Underlying Common Stock has been converted or exchanged, and any security issued with respect thereto upon any stock
dividend, split or similar event until, in the case of any such security, the earlier of (1) the second anniversary of the Issue Date, (2) its effective registration under the Securities Act and resale in accordance with a Shelf
Registration Statement, (3) expiration of the holding period that would be applicable thereto under Rule 144(k) or (4) its sale to the public pursuant to Rule 144 (or any similar provision then in force, but not Rule 144A) under the
Securities Act, and as a result of the event or circumstance described in any of the foregoing clauses (1) through (4), the legend with respect to transfer restrictions required under the Indenture is removed or removable in accordance with the
terms of the Indenture or such legend, as the case may be. 
 “Registration Default” has the meaning set forth in
Section 2(f) hereof. 
 “Registration Default Period” has the meaning set forth in Section 2(f) hereof.

 “Rule 144” means Rule 144 under the Securities Act, as such Rule may be amended from time to time, or any similar rule or
regulation hereafter adopted by the SEC. 
 “Rule 144A” means Rule 144A under the Securities Act, as such Rule may be
amended from time to time, or any similar rule or regulation hereafter adopted by the SEC. 
 “Rule 405” means Rule 405
under the Securities Act, as such Rule may be amended from time to time, or any similar rule or regulation hereafter adopted by the SEC. 
 “Rule 424” means Rule 424 under the Securities Act, as such Rule may be amended from time to time, or any similar rule or regulation hereafter adopted by the SEC. 
  

 3 

 “Rule 433” means Rule 433 under the Securities Act, as such Rule may be amended from
time to time, or any similar rule or regulation hereafter adopted by the SEC. 
 “SEC” means the Securities and Exchange
Commission. 
 “Securities” means the 2.50% Convertible Senior Notes Due 2036 of the Company to be purchased pursuant to the
Purchase Agreement, including any Securities purchased by the Initial Purchasers upon exercise of their over-allotment option to purchase additional Securities pursuant to the Purchase Agreement. 
 “Securities Act” means the Securities Act of 1933, as amended, and the rules and regulations promulgated by the SEC thereunder.

 “Shelf Registration Statement” has the meaning set forth in Section 2(a) hereof, including amendments to such
registration statement, all exhibits to such registration statement and all materials incorporated by reference in such registration statement. 
 “Special Counsel” means Davis Polk & Wardwell or one such other successor counsel as shall be specified by the Holders of a majority of the Registrable Securities, but which may, with the written consent of the
Initial Purchasers (which shall not be unreasonably withheld), be another nationally recognized law firm experienced in securities law matters designated by the Company. For purposes of determining Holders of a majority of the Registrable Securities
in this definition, Holders of Securities shall be deemed to be the Holders of the number of shares of Underlying Common Stock into which such Securities are or would be convertible as of the date the consent is requested. 
 “Supplemental Indenture” means the Second Supplemental Indenture, dated as of December 15, 2006, between the Company and the
Trustee, providing for the terms of the Securities. 
 “Trustee” means Wells Fargo Bank, National Association., the
successor trustee under the Indenture. 
 “Underlying Common Stock” means the Common Stock into which the Securities are
convertible or issued upon any such conversion. 
 Section 2. Shelf Registration. (a) The Company shall prepare and file or
cause to be prepared and filed with the SEC no later than the date (the “Filing Deadline”) that is 270 days after the Issue Date, a registration statement for an offering to be made on a delayed or continuous basis pursuant to Rule
415 of the Securities Act registering the resale from time to time by Holders of the Registrable Securities (a “Shelf Registration Statement”). The Shelf Registration Statement shall be on any appropriate form permitting
registration of 
  

 4 

 the Registrable Securities for resale by the Holders. Each Shelf Registration Statement that is filed on Form S-3 shall
be designated by the Company as an Automatic Shelf Registration Statement but only if the Company is then eligible to file an Automatic Shelf Registration Statement on Form S-3 for the purposes contemplated by this Agreement. If the Company is
eligible pursuant to Rule 430B(b) to omit from the related Prospectus the identities of selling securityholders and the amounts of securities to be registered on their behalf, the Company shall prepare and file each Shelf Registration Statement in a
manner as to permit such omission and to allow for the subsequent filing of such information in a Prospectus pursuant to Rule 424(b) in the manner contemplated by Rule 430B(d). The Company shall use its reasonable efforts to cause a Shelf
Registration Statement to be declared effective under the Securities Act no later than the date (the “Effectiveness Deadline”) that is 300 days after the Issue Date, and, subject to the provisions hereof, to keep a Shelf
Registration Statement continuously effective under the Securities Act until the expiration of the Effectiveness Period. Each Holder that became a Notice Holder within 20 days of receiving notice from the Company pursuant to Section 3(c) below
of the Company’s intention to file the Shelf Registration Statement shall be named as a selling securityholder in the initial Shelf Registration Statement and the related Prospectus in such a manner as to permit such Holder to deliver the
Prospectus to purchasers of Registrable Securities in accordance with applicable law. None of the Company’s security holders (other than the Holders) shall have the right to include any of the Company’s securities in a Shelf Registration
Statement. 
 (b) If a Shelf Registration Statement covering resales of the Registrable Securities ceases to be effective for any reason at
any time during the Effectiveness Period (other than because all securities registered thereunder shall have been resold pursuant thereto or shall have otherwise ceased to be Registrable Securities), or if such Shelf Registration Statement
constituted an Automatic Shelf Registration Statement at the time it was filed with the SEC and ceases to constitute an Automatic Shelf Registration Statement, the Company shall use its reasonable efforts to obtain the prompt withdrawal of any order
suspending the effectiveness thereof, and, subject to the provisions of this Agreement, in any event shall within 30 days of such cessation of effectiveness amend the Shelf Registration Statement in a manner reasonably expected to obtain the
withdrawal of the order suspending the effectiveness thereof, or file an additional Shelf Registration Statement so that all Registrable Securities outstanding as of the date of such filing are covered by a Shelf Registration Statement. If a new
Shelf Registration Statement is filed, the Company shall use its reasonable efforts to cause the new Shelf Registration Statement to become effective as promptly as is practicable after such filing and to keep the new Shelf Registration Statement
continuously effective until the end of the Effectiveness Period, subject to the provisions of this Agreement. 
 (c) The Company shall amend
and supplement the Prospectus and amend the Shelf Registration Statement if required by the rules, regulations or 
  

 5 

 instructions applicable to the registration form used by the Company for such Shelf Registration Statement or file a new
Shelf Registration Statement, if required by the Securities Act, or any other documents necessary to name a Notice Holder as a selling securityholder pursuant to Section 2(e) below. 
 (d) The Company agrees that, unless it obtains the prior consent of the Holders of a majority of the Registrable Securities that are registered under the
Shelf Registration Statement at such time or the consent of the managing underwriters in connection with any underwritten offering of Registrable Securities, and each Holder agrees that, unless it obtains the prior written consent of the Company and
any such underwriters, it will not make any offer relating to the Securities that would (i) constitute an Issuer Free Writing Prospectus, or (ii) that would otherwise constitute a Free Writing Prospectus required to be filed with the SEC.
The Company represents that any Issuer Free Writing Prospectus prepared by it or authorized by it in writing for use by such Holder will not include any information that conflicts with the information contained in the Shelf Registration Statement or
the Prospectus and, any such Issuer Free Writing Prospectus, when taken together with the information in the Shelf Registration Statement and the Prospectus, will not include any untrue statement of a material fact or omit to state any material fact
necessary in order to make the statements therein, in light of the circumstances under which they were made, not misleading. 
 (e) Subject
to the Company’s rights to suspend the use of the Shelf Registration Statement or the Prospectus as provided herein, each Holder may sell Registrable Securities pursuant to a Shelf Registration Statement and related Prospectus only in
accordance with this Section 2(e) and Section 3(h). Each Holder wishing to sell Registrable Securities pursuant to a Shelf Registration Statement and related Prospectus shall deliver a Notice and Questionnaire to the Company prior to any
intended distribution of Registrable Securities under the Shelf Registration Statement. From and after the date the initial Shelf Registration Statement is declared effective, the Company shall, as promptly as practicable after the date a Notice and
Questionnaire is delivered, and in any event upon the later of (x) 15 Business Days after such date or (y) five Business Days after the expiration of any Deferral Period in effect when the Notice and Questionnaire is delivered or put into
effect within 15 Business Days of such delivery date: 
 (i) subject to the Company’s rights to suspend the use of
the Shelf Registration Statement or the Prospectus as provided herein, if required by applicable law, file with the SEC a post-effective amendment to the Shelf Registration Statement or prepare and, if required by applicable law, file a supplement
to the related Prospectus or a supplement or amendment to any document incorporated therein by reference or file a new Shelf Registration Statement or any other required document so that the Holder delivering such Notice and Questionnaire is named
as a selling securityholder in a Shelf Registration Statement and the related Prospectus 
  

 6 

 in such a manner as to permit such Holder to deliver such Prospectus to purchasers of the Registrable
Securities in accordance with applicable law and, if the Company shall file a post-effective amendment to a Shelf Registration Statement or shall file a new Shelf Registration Statement, the Company shall use its reasonable efforts to cause such
post-effective amendment or new Shelf Registration Statement to be declared effective under the Securities Act as promptly as is practicable, but in any event by the date (the “Amendment Effectiveness Deadline”) that is 45 days
after the date such post-effective amendment or new Shelf Registration Statement is required by this clause to be filed; 
 (ii) provide such Holder copies of any documents filed pursuant to Section 2(e)(i); and 
 (iii)
notify such Holder as promptly as practicable after the effectiveness under the Securities Act of any new Shelf Registration Statement or post-effective amendment filed pursuant to Section 2(e)(i); 
 provided that if such Notice and Questionnaire is delivered during a Deferral Period, the Company shall so inform the Holder delivering such Notice and
Questionnaire and shall take the actions set forth in clauses (i), (ii) and (iii) above upon expiration of the Deferral Period in accordance with Section 3(h). Notwithstanding anything contained herein to the contrary, (i) the
Company shall be under no obligation to name any Holder that is not a Notice Holder as a selling securityholder in any Shelf Registration Statement or related Prospectus, (ii) the Amendment Effectiveness Deadline shall be further extended by up
to an additional ten Business Days from the expiration of a Deferral Period, and (iii) the Company shall not be under any obligation to file more than one prospectus supplement or post-effective amendment to a Shelf Registration Statement in
any calendar quarter or file a new Shelf Registration Statement if the existing Shelf Registration Statement was filed in the same calendar quarter. 
 (f) The parties hereto agree that the Holders of Registrable Securities will suffer damages, and that it would not be feasible to ascertain the extent of such damages with precision, if: 
 (i) a Shelf Registration Statement has not been filed on or prior to the Filing Deadline, 
 (ii) a Shelf Registration Statement has not been declared effective under the Securities Act on or prior to the Effectiveness
Deadline, 
 (iii) the Company has failed to perform its obligations set forth in Section 2(e)(i) within the time
period required by Section 2(e), 
  

 7 

 (iv) a new Shelf Registration Statement or a post-effective amendment to a Shelf
Registration Statement filed pursuant to Section 2(e)(i) has not become effective under the Securities Act on or prior to the Amendment Effectiveness Deadline as it may be extended pursuant to Section 2(e), 
 (v) a supplement to a Prospectus is required to be filed with the SEC pursuant to Section 2(e)(i) and fails to be filed with
the SEC within the prescribed period and in the manner set forth in Section 2(e) above (a date such filing is required to be made, an “Additional Filing Deadline”), 
 (vi) the aggregate duration of Deferral Periods in any period exceeds the number of days permitted in respect of such period
pursuant to Section 3(h) hereof, or 
 (vii) the number of Deferral Periods in any period exceeds the number
permitted in respect of such period pursuant to Section 3(h) hereof. 
 Each event described in any of the foregoing clauses (i) through
(vii) is individually referred to herein as a “Registration Default.” For purposes of this Agreement, each Registration Default set forth above shall begin and end on the dates set forth in the table set forth below:

  

					
	 Type of
 Registration

Default by
 Clause
	  	 Beginning Date
	  	 Ending Date

	(i)	  	Filing Deadline	  	the date a Shelf Registration Statement is filed
			
	(ii)	  	Effectiveness Deadline	  	the date a Shelf Registration Statement becomes effective under the Securities Act
			
	(iii)	  	the date by which the Company is required to perform its obligations under Section 2(e)(i)	  	the date the Company performs its obligations set forth in Section 2(e)(i)
			
	(iv)	  	the Amendment Effectiveness Deadline	  	the date the applicable post-effective amendment to a Shelf Registration Statement or a new Shelf Registration Statement becomes effective under the Securities Act

  

 8 

					
	 Type of
 Registration
 Default by
 Clause
	  	 Beginning Date
	  	 Ending Date

	(v)	  	the Additional Filing Deadline	  	the date the applicable supplement to a Prospectus is filed with the SEC in the manner set forth in Section 2(e)
			
	(vi)	  	the date on which the aggregate duration of Deferral Periods in any period exceeds the number of days permitted by Section 3(h)	  	termination of the Deferral Period that caused the limit on the aggregate duration of Deferral Periods to be exceeded
			
	(vii)	  	the date of commencement of a Deferral Period that causes the number of Deferral Periods to exceed the number permitted by Section 3(h)	  	termination of the Deferral Period that caused the number of Deferral Periods to exceed the number permitted by Section 3(h)

 For purposes of this Agreement, Registration Defaults shall begin on the dates set forth in the table above and
shall continue until the ending dates set forth in the table above. 
 Commencing on (and including) any date that a Registration Default has
begun and ending on (but excluding) the next date on which there are no Registration Defaults that have occurred and are continuing (a “Registration Default Period”), the Company shall pay to Record Holders of Registrable Securities
in respect of each day in the Registration Default Period, additional interest in respect of any Security, at a rate per annum equal to 0.25% of the aggregate principal amount of such Security for the first 90 days of such Registration Default
and a rate per annum equal to 0.50% of the aggregate principal amount of such Security thereafter (the “Additional Interest”); provided that in no event shall Additional Interest accrue at a rate per annum in excess of 0.50%
of the aggregate principal amount of such Security accrue after the second anniversary of the Issue Date; provided, further, that in the case of a Registration Default Period that is in effect solely as a result of a Registration
Default of the type described in clause (iii), (iv) or (v) of the preceding paragraph, such Additional Interest Amount shall be paid only to the Holders (as set forth in the succeeding paragraph) that have delivered Notices and
Questionnaires that caused the Company to incur the obligations set forth in Section 2(e) the non-performance of which is the basis of such Registration Default. Notwithstanding the foregoing, no Additional Interest shall accrue as to any
Registrable Security from and after the date such security is no longer a Registrable Security. The rate of accrual of the Additional Interest with respect to any period shall not exceed the rate provided for in this paragraph notwithstanding the
occurrence of multiple concurrent Registration Defaults. 
  

 9 

 The Additional Interest shall accrue from the first day of the applicable Registration Default Period,
and shall be payable on each Interest Payment Date during the Registration Default Period (and on the Interest Payment Date next succeeding the end of the Registration Default Period if the Registration Default Period does not end on a Interest
Payment Date) to the Record Holders of the Registrable Securities entitled thereto; provided that any Additional Interest accrued with respect to any Security or portion thereof redeemed by the Company on a redemption date, purchased by the
Company on a repurchase date or converted into Underlying Common Stock on a conversion date prior to the Interest Payment Date, shall, in any such event, be paid instead to the Holder who submitted such Security or portion thereof for redemption,
purchase or conversion on the applicable redemption date, repurchase date or conversion date, as the case may be, on such date (or promptly following the conversion date, in the case of conversion), unless the redemption date or the repurchase date,
as the case may be, falls after the 15th day immediately preceding the Interest Payment Date and on or prior to
the corresponding Interest Payment Date; and provided further, that, in the case of a Registration Default of the type described in clause (iii), (iv) or (v) of the first paragraph of this Section 2(f) such Additional Interest
shall be paid only to the Holders entitled thereto by check mailed to the address set forth in the Notice and Questionnaire delivered by such Holder. The Trustee shall be entitled, on behalf of registered holders of Securities, to seek any available
remedy for the enforcement of this Agreement, including for the payment of such Additional Interest. Notwithstanding the foregoing, the parties agree that the sole damages payable for a violation of the terms of this Agreement with respect to which
Additional Interest are expressly provided shall be such Additional Interest. Nothing shall preclude any Holder from pursuing or obtaining specific performance or other equitable relief with respect to this Agreement. 
 All of the Company’s obligations set forth in this Section 2(f) that are outstanding with respect to any Registrable Security at the time such
security ceases to be a Registrable Security shall survive until such time as all such obligations with respect to such security have been satisfied in full (notwithstanding termination of this Agreement pursuant to Section 8(k)). 

The parties hereto agree that the Additional Interest provided for in this Section 2(f) constitutes a reasonable estimate of the damages that may
be incurred by Holders of Registrable Securities by reason of the failure of a Shelf Registration Statement to be filed or declared effective or available for effecting resales of Registrable Securities in accordance with the provisions hereof.

  

 10 

 Section 3. Registration Procedures. In connection with the registration obligations of the
Company under Section 2 hereof, the Company shall: 
 (a) Before filing any Shelf Registration Statement or Prospectus or any amendments
or supplements thereto with the SEC, furnish to the Initial Purchasers and the Special Counsel of such offering, if any, copies of all such documents proposed to be filed at least three Business Days prior to the filing of such Shelf Registration
Statement or amendment thereto or Prospectus or supplement thereto. 
 (b) Subject to Section 3(h) prepare and file with the SEC such
amendments and post-effective amendments to each Shelf Registration Statement as may be necessary to keep such Shelf Registration Statement continuously effective during the Effectiveness Period; cause the related Prospectus to be supplemented by
any required prospectus supplement, and as so supplemented to be filed pursuant to Rule 424 (or any similar provisions then in force) under the Securities Act; and use its reasonable efforts to comply with the provisions of the Securities Act
applicable to it with respect to the disposition of all securities covered by such Shelf Registration Statement during the Effectiveness Period in accordance with the intended methods of disposition by the sellers thereof set forth in such Shelf
Registration Statement as so amended or such Prospectus as so supplemented. 
 (c) As promptly as practicable give notice to the Notice
Holders, the Initial Purchasers and the Special Counsel, (i) when any Prospectus, prospectus supplement, Shelf Registration Statement or post-effective amendment to a Shelf Registration Statement has been filed with the SEC and, with respect to
a Shelf Registration Statement or any post-effective amendment, when the same has been declared effective; provided, however, that the Company shall not be required by this clause (i) to notify any Holder of the filing of a
supplement to any Prospectus that names one or more other Holders as selling securityholders, (ii) of any request, following the effectiveness of the initial Shelf Registration Statement under the Securities Act, by the SEC or any other federal
or state governmental authority for amendments or supplements to any Shelf Registration Statement or related Prospectus or for additional information, (iii) of the issuance by the SEC or any other federal or state governmental authority of any
stop order suspending the effectiveness of any Shelf Registration Statement or the initiation or threatening of any proceedings for that purpose, (iv) of the receipt by the Company of any notification with respect to the suspension of the
qualification or exemption from qualification of any of the Registrable Securities for sale in any jurisdiction or the initiation or threatening of any proceeding for such purpose, (v) of the occurrence of, but not the nature of or details
concerning, a Material Event; provided, that no notice by the Company shall be required pursuant to this clause (v) if the Company either promptly files a supplement to update the Prospectus or a Current Report on Form 8-K or other
appropriate Exchange Act report that is incorporated by reference into the Registration Statement, which, in any case, contains the requisite information with respect to such Material Event that results in such Registration Statement no longer
containing any untrue statement of a material fact or omitting to state a material fact necessary to make the statement 
  

 11 

 contained therein not misleading and (vi) of the determination by the Company that a post-effective amendment to a
Shelf Registration Statement will be filed with the SEC, which notice may, at the discretion of the Company (or as required pursuant to Section 3(h)) state that it constitutes a Deferral Notice, in which event the provisions of
Section 3(h) shall apply. 
 (d) Use its reasonable efforts to obtain the withdrawal of any order suspending the effectiveness of a
Shelf Registration Statement or the lifting of any suspension of the qualification (or exemption from qualification) of any of the Registrable Securities for sale in any jurisdiction in which they have been qualified for sale, in either case at the
earliest possible moment, and provide prompt notice to each Notice Holder and the Initial Purchasers of the withdrawal of any such order. 
 (e) As promptly as practicable furnish to each Notice Holder, the Special Counsel and the Initial Purchasers, upon request and without charge, at least one conformed copy of each Shelf Registration Statement and any amendment thereto,
including exhibits and all documents incorporated or deemed to be incorporated therein by reference, unless any such document is available on the Electronic Data Gathering Analysis and Retrieval system of the SEC. 
 (f) During the Effectiveness Period, deliver to each Notice Holder, the Special Counsel, if any, and the Initial Purchasers, in connection with any sale
of Registrable Securities pursuant to a Shelf Registration Statement, without charge, as many copies of the Prospectus relating to such Registrable Securities (including each preliminary prospectus) and any amendment or supplement thereto as such
Notice Holder may reasonably request; and the Company hereby consents (except during such periods that a Deferral Notice is outstanding and has not been revoked) to the use of such Prospectus or each amendment or supplement thereto by each Notice
Holder in connection with any offering and sale of the Registrable Securities covered by such Prospectus or any amendment or supplement thereto in the manner set forth therein. 
 (g) Prior to any public offering of the Registrable Securities pursuant to a Shelf Registration Statement, use its reasonable efforts to register or
qualify or cooperate with the Notice Holders and the Special Counsel in connection with the registration or qualification (or exemption from such registration or qualification) of such Registrable Securities for offer and sale under the securities
or Blue Sky laws of such jurisdictions within the United States as any Notice Holder reasonably requests in writing (which request may be included in the Notice and Questionnaire); prior to any public offering of the Registrable Securities pursuant
to a Shelf Registration Statement, use its reasonable efforts to keep each such registration or qualification (or exemption therefrom) effective during the Effectiveness Period in connection with such Notice Holder’s offer and sale of
Registrable Securities pursuant to such registration or qualification (or exemption therefrom) and do any and all other acts or things reasonably necessary or advisable to enable the disposition in such jurisdictions of such Registrable 

 

 12 

 Securities in the manner set forth in the Shelf Registration Statement and the related Prospectus; provided that
the Company will not be required to (i) qualify as a foreign corporation or as a dealer in securities in any jurisdiction where it would not otherwise be required to qualify but for this Agreement or (ii) take any action that would subject
it to general service of process in suits or to taxation in any such jurisdiction where it is not then so subject. 
 (h) Upon (A) the
issuance by the SEC of a stop order suspending the effectiveness of a Shelf Registration Statement or the initiation of proceedings with respect to a Shelf Registration Statement under Section 8(d) or 8(e) of the Securities Act, (B) the
occurrence of any event or the existence of any fact (a “Material Event”) as a result of which a Shelf Registration Statement shall contain any untrue statement of a material fact or omit to state any material fact required to be
stated therein or necessary to make the statements therein not misleading, or any Prospectus shall contain any untrue statement of a material fact or omit to state any material fact required to be stated therein or necessary to make the statements
therein, in the light of the circumstances under which they were made, not misleading, or (C) the occurrence or existence of any pending corporate development that, in the reasonable discretion of the Company, makes it appropriate to suspend
the availability of a Shelf Registration Statement and the related Prospectus: 
 (i) in the case of clause
(B) above, as promptly as practicable prepare and file, if necessary pursuant to applicable law, a post-effective amendment to such Shelf Registration Statement or a supplement to the related Prospectus or any document incorporated therein by
reference or file any other required document that would be incorporated by reference into such Shelf Registration Statement and Prospectus so that such Shelf Registration Statement does not contain any untrue statement of a material fact or omit to
state any material fact required to be stated therein or necessary to make the statements therein not misleading, and such Prospectus does not contain any untrue statement of a material fact or omit to state any material fact required to be stated
therein or necessary to make the statements therein, in the light of the circumstances under which they were made, not misleading, as thereafter delivered to the purchasers of the Registrable Securities being sold thereunder, and, in the case of a
post-effective amendment to a Shelf Registration Statement, use its reasonable efforts to cause it to be declared effective as promptly as is practicable, and 
 (ii) give notice to the Notice Holders, and the Special Counsel, if any, that the availability of a Shelf Registration Statement is
suspended (a “Deferral Notice”). 
 The Company will use its reasonable efforts to ensure that the use of the Prospectus may be resumed
(x) in the case of clause (A) above, as promptly as is practicable, (y) in the case of clause (B) above, as soon as, in the sole judgment of 
  

 13 

 the Company, public disclosure of such Material Event would not be prejudicial to or contrary to the interests of the
Company or, if necessary to avoid unreasonable burden or expense, as soon as practicable thereafter and (z) in the case of clause (C) above, as soon as in the reasonable discretion of the Company, such suspension is no longer appropriate.
Any such period during which the availability of the Shelf Registration Statement and any Prospectus is suspended (the “Deferral Period”) shall, without incurring any obligation to pay Additional Interest pursuant to
Section 2(f), not exceed 30 consecutive days; provided that the aggregate duration of any Deferral Periods shall not exceed 30 days in any 90-day period (or 60 days in any 90-day period in the event of a Material Event pursuant to which
the Company has delivered a second notice as required below) or 90 days in any 12 month period; provided that in the case of a Material Event relating to an acquisition or a probable acquisition or financing, recapitalization, business
combination or other similar transaction, the Company may, without incurring any obligation to pay Additional Interest pursuant to Section 2(f), deliver to Notice Holders a second notice to the effect set forth above, which shall have the
effect of extending the Deferral Period by up to an additional 30 days, or such shorter period of time as is specified in such second notice. 
 (i) If requested in writing in connection with a disposition of Registrable Securities pursuant to a Shelf Registration Statement, make reasonably available for inspection during normal business hours by a representative for the Notice
Holders of such Registrable Securities, any broker-dealers, attorneys and accountants retained by such Notice Holders, and any attorneys or other agents retained by a broker-dealer engaged by such Notice Holders, all relevant financial and other
records and pertinent corporate documents and properties of the Company and its subsidiaries, and cause the appropriate officers, directors and employees of the Company and its subsidiaries to make reasonably available for inspection during normal
business hours on reasonable notice all relevant information reasonably requested by such representative for the Notice Holders, or any such broker-dealers, attorneys or accountants in connection with such disposition, in each case as is customary
for similar “due diligence” examinations; provided that such persons shall first agree in writing with the Company that any non-public information shall be used solely for the purposes of satisfying “due diligence”
obligations under the Securities Act and exercising rights under this Agreement and shall be kept confidential by such persons, unless (i) disclosure of such information is required by court or administrative order or is necessary to respond to
inquiries of regulatory authorities, (ii) in the opinion of Special Counsel, disclosure of such information is required by law (including any disclosure requirements pursuant to federal securities laws in connection with the filing of any Shelf
Registration Statement or the use of any prospectus referred to in this Agreement), (iii) such information becomes generally available to the public other than as a result of a disclosure or failure to safeguard by any such person or
(iv) such information becomes available to any such person from a source other than the Company and such source is not bound by a confidentiality agreement, and provided further that the 
  

 14 

 foregoing inspection and information gathering shall, to the greatest extent possible, be coordinated on behalf of all
the Notice Holders and the other parties entitled thereto by the Special Counsel. Any person legally compelled to disclose any such confidential information made available for inspection shall provide the Company with prompt prior written notice of
such requirement so that the Company may seek a protective order or other appropriate remedy. 
 (j) Comply in all material respects with all
applicable rules and regulations of the SEC and make generally available to its securityholders an earning statement (which need not be audited) satisfying the provisions of Section 11(a) of the Securities Act and Rule 158 thereunder (or any
similar rule promulgated under the Securities Act) for a 12-month period commencing on the first day of the first fiscal quarter of the Company commencing after the effective date of a Shelf Registration Statement. 
 (k) Cooperate with each Notice Holder to facilitate the timely preparation and delivery of certificates representing Registrable Securities sold or to be
sold pursuant to a Shelf Registration Statement, which certificates shall not bear any restrictive legends, and cause such Registrable Securities to be in such denominations as are permitted by the Indenture and registered in such names as such
Notice Holder may request in writing at least two Business Day prior to any sale of such Registrable Securities. 
 (l) Provide a CUSIP
number for all Registrable Securities covered by each Shelf Registration Statement not later than the effective date of such Shelf Registration Statement and provide the Trustee and the transfer agent for the Common Stock with printed certificates
for the Registrable Securities that are in a form eligible for deposit with The Depository Trust Company. 
 (m) Cooperate and assist in any
filings required to be made with the National Association of Securities Dealers, Inc. 
 (n) Upon (i) the filing of the initial Shelf
Registration Statement and (ii) the effectiveness of the initial Shelf Registration Statement, announce the same, in each case by release to PR Newswire. 
 Section 4. Holder’s Obligations. (a) Each Holder agrees, by acquisition of the Registrable Securities, that no Holder shall be entitled to sell any of such Registrable Securities pursuant to a
Shelf Registration Statement or to receive a Prospectus relating thereto, unless such Holder has furnished the Company with a Notice and Questionnaire as required pursuant to Section 2(e) hereof (including the information required to be
included in such Notice and Questionnaire) and the information set forth in the next sentence. Each Notice Holder agrees promptly to furnish to the Company all information required to be disclosed in order to make the information previously
furnished to the Company by such Notice Holder not misleading and any other information regarding such Notice Holder and the distribution of such Registrable Securities as the Company may from time to time 
  

 15 

 reasonably request. Any sale of any Registrable Securities by any Holder shall constitute a representation and warranty
by such Holder that the information relating to such Holder and its plan of distribution is as set forth in the Prospectus delivered by such Holder in connection with such disposition, that such Prospectus does not as of the time of such sale
contain any untrue statement of a material fact relating to or provided by such Holder or its plan of distribution and that such Prospectus does not as of the time of such sale omit to state any material fact relating to or provided by such Holder
or its plan of distribution necessary to make the statements in such Prospectus, in the light of the circumstances under which they were made, not misleading. 
 (b) Upon receipt of any Deferral Notice, each Notice Holder agrees not to sell any Registrable Securities pursuant to any Shelf Registration Statement until such Notice Holder’s receipt of copies of the
supplemented or amended Prospectus provided for in Section 3(h)(i), or until it is advised in writing by the Company that the Prospectus may be used. 
 Section 5. Registration Expenses. The Company shall bear all fees and expenses incurred in connection with the performance by the Company of its obligations under Sections 2 and 3 of this Agreement whether
or not any Shelf Registration Statement is declared effective. Such fees and expenses shall include, without limitation, (i) all registration and filing fees (including, without limitation, fees and expenses (x) with respect to filings
required to be made with the National Association of Securities Dealers, Inc. and (y) of compliance with federal and state securities or Blue Sky laws (including, without limitation, reasonable fees and disbursements of the Special Counsel in
connection with Blue Sky qualifications of the Registrable Securities under the laws of such jurisdictions as Notice Holders of a majority of the Registrable Securities being sold pursuant to a Shelf Registration Statement may designate),
(ii) printing expenses (including, without limitation, expenses of printing certificates for Registrable Securities in a form eligible for deposit with The Depository Trust Company), (iii) duplication expenses relating to copies of any
Shelf Registration Statement or Prospectus delivered to any Holders hereunder, (iv) fees and disbursements of counsel for the Company in connection with any Shelf Registration Statement, (v) reasonable fees and disbursements of the Trustee
and its counsel and of the registrar and transfer agent for the Common Stock and (vi) the reasonable fees and disbursements of the Special Counsel, which fees and expenses shall not exceed $20,000. In addition, the Company shall pay the
internal expenses of the Company (including, without limitation, all salaries and expenses of officers and employees performing legal or accounting duties), the expense of any annual audit, the fees and expenses incurred in connection with the
listing by the Company of the Registrable Securities on any securities exchange on which similar securities of the Company are then listed and the fees and expenses of any person, including special experts, retained by the Company. Notwithstanding
the provisions of this Section 5, each seller of Registrable Securities shall pay any broker’s commission, agency fee or underwriter’s discount or commission in connection with the sale of the Registrable Securities under a Shelf
Registration Statement. 
  

 16 

 Section 6. Indemnification and Contribution.  
 (a) The Company agrees to indemnify and hold harmless each Notice Holder, each person, if any, who controls any Notice Holder within the meaning of either
Section 15 of the Securities Act or Section 20 of the Exchange Act, and each affiliate of any Notice Holder within the meaning of Rule 405 under the Securities Act from and against any and all losses, claims, damages and liabilities
(including, without limitation, any legal or other expenses reasonably incurred in connection with defending or investigating any such action or claim) caused by any untrue statement or alleged untrue statement of a material fact contained in any
Shelf Registration Statement or any amendment thereof, any preliminary prospectus or any Prospectus (as amended or supplemented if the Company shall have furnished any amendments or supplements thereto) or any Issuer Free Writing Prospectus prepared
by it or authorized by it in writing for use by such Holder (as amended or supplemented if the Company shall have furnished any amendments or supplements thereto), caused by any omission or alleged omission to state therein a material fact required
to be stated therein or necessary to make the statements therein not misleading, except insofar as such losses, claims, damages or liabilities are caused by any such untrue statement or omission or alleged untrue statement or omission based upon
information relating to any Holder furnished to the Company in writing by such Holder expressly for use therein; provided that the foregoing indemnity shall not inure to the benefit of any Holder (or to the benefit of any person controlling
such Holder) from whom the person asserting such losses, claims or liabilities purchased the Registrable Securities, if a copy of the Prospectus or the Issuer Free Writing Prospectus (both as then amended or supplemented if the Company shall have
furnished any amendments or supplements thereto) was not sent or given by or on behalf of such Holder to such person, if required by law so to have been delivered at or prior to the written confirmation of the sale of the Registrable Securities to
such person, and if the Prospectus or the Issuer Free Writing Prospectus (both as so amended or supplemented) would have cured the defect giving rise to such losses, claims, damages or liabilities, unless such failure is the result of noncompliance
by the Company with Section 2(b) hereof. 
 (b) Each Holder agrees severally and not jointly to indemnify and hold harmless the Company
and its directors, its officers who sign any Shelf Registration Statement and each person, if any, who controls the Company (within the meaning of either Section 15 of the Securities Act or Section 20 of the Exchange Act) or any other
Holder, to the same extent as the foregoing indemnity from the Company to such Holder, but only with reference to information relating to such Holder furnished to the Company in writing by such Holder expressly for use in such Shelf Registration
Statement, Prospectus or Issuer Free Writing Prospectus or amendment or supplement thereto. In no event shall the liability of any Holder hereunder be greater in amount than the dollar amount of the proceeds received by such Holder upon the sale of
the Registrable Securities pursuant to the Shelf Registration Statement giving rise to such indemnification obligation. 
  

 17 

 (c) In case any proceeding (including any governmental investigation) shall be instituted involving any
person in respect of which indemnity may be sought pursuant to Section 6(a) or 6(b) hereof, such person (the “indemnified party”) shall promptly notify the person against whom such indemnity may be sought (the
“indemnifying party”) in writing and the indemnifying party, upon request of the indemnified party, shall retain counsel reasonably satisfactory to the indemnified party to represent the indemnified party and any others the
indemnifying party may designate in such proceeding and shall pay the reasonable fees and disbursements of such counsel related to such proceeding. In any such proceeding, any indemnified party shall have the right to retain its own counsel, but the
fees and expenses of such counsel shall be at the expense of such indemnified party unless (i) the indemnifying party and the indemnified party shall have mutually agreed to the retention of such counsel or (ii) the named parties to any
such proceeding (including any impleaded parties) include both the indemnifying party and the indemnified party and representation of both parties by the same counsel would be inappropriate due to actual or potential differing interests between
them. It is understood that the indemnifying party shall not, in respect of the legal expenses of any indemnified party in connection with any proceeding or related proceedings in the same jurisdiction, be liable for the fees and expenses of more
than one separate firm (in addition to any local counsel) for all such indemnified parties and that all such fees and expenses shall be reimbursed as they are incurred. Such firm shall be designated in writing by, in the case of parties indemnified
pursuant to Section 6(a), the Holders of a majority (with Holders of Securities deemed to be the Holders, for purposes of determining such majority, of the number of shares of Underlying Common Stock into which such Securities are or would be
convertible as of the date on which such designation is made) of the Registrable Securities covered by the Shelf Registration Statement held by Holders that are indemnified parties pursuant to Section 6(a) and, in the case of parties
indemnified pursuant to Section 6(b), the Company. The indemnifying party shall not be liable for any settlement of any proceeding effected without its written consent, but if settled with such consent or if there be a final judgment for the
plaintiff, the indemnifying party agrees to indemnify the indemnified party from and against any loss or liability by reason of such settlement or judgment. Notwithstanding the foregoing sentence, if at any time an indemnified party shall have
requested an indemnifying party to reimburse the indemnified party for fees and expenses of counsel as contemplated by the second and third sentences of this paragraph, the indemnifying party agrees that it shall be liable for any settlement of any
proceeding effected without its written consent if (i) such settlement is entered into more than 30 days after receipt by such indemnifying party of the aforesaid request and (ii) such indemnifying party shall not have reimbursed the
indemnified party in accordance with such request prior to the date of such settlement. No indemnifying party shall, without the prior written consent of the indemnified party, effect any 
  

 18 

 settlement of any pending or threatened proceeding in respect of which any indemnified party is or could have been a
party and indemnity could have been sought hereunder by such indemnified party, unless such settlement includes an unconditional release of such indemnified party from all liability on claims that are the subject matter of such proceeding.

 (d) To the extent that the indemnification provided for in Section 6(a) or 6(b) is unavailable to an indemnified party or
insufficient in respect of any losses, claims, damages or liabilities referred to therein, then each indemnifying party under such paragraph, in lieu of indemnifying such indemnified party thereunder, shall contribute to the amount paid or payable
by such indemnified party as a result of such losses, claims, damages or liabilities (i) in such proportion as is appropriate to reflect the relative benefits received by the indemnifying party or parties on the one hand and the indemnified
party or parties on the other hand or (ii) if the allocation provided by clause (i) above is not permitted by applicable law, in such proportion as is appropriate to reflect not only the relative benefits referred to in clause
(i) above but also the relative fault of the indemnifying party or parties on the one hand and of the indemnified party or parties on the other hand in connection with the statements or omissions that resulted in such losses, claims, damages or
liabilities, as well as any other relevant equitable considerations. The relative benefits received by the Company shall be deemed to be equal to the total net proceeds from the initial placement pursuant to the Purchase Agreement (before deducting
expenses) of the Registrable Securities to which such losses, claims, damages or liabilities relate. The relative benefits received by any Holder shall be deemed to be equal to the value of receiving registration rights under this Agreement for the
Registrable Securities. The relative fault of the Holders on the one hand and the Company on the other hand shall be determined by reference to, among other things, whether the untrue or alleged untrue statement of a material fact or the omission or
alleged omission to state a material fact relates to information supplied by the Holders or by the Company, and the parties’ relative intent, knowledge, access to information and opportunity to correct or prevent such statement or omission. The
Holders’ respective obligations to contribute pursuant to this Section 6(d) are several in proportion to the respective number of Registrable Securities they have sold pursuant to a Shelf Registration Statement, and not joint. 

The parties hereto agree that it would not be just and equitable if contribution pursuant to this Section 6(d) were determined by pro rata
allocation or by any other method of allocation that does not take into account the equitable considerations referred to in the immediately preceding paragraph. The amount paid or payable by an indemnified party as a result of the losses, claims,
damages or liabilities referred to in the immediately preceding paragraph shall be deemed to include, subject to the limitations set forth above, any legal or other expenses reasonably incurred by such indemnified party in connection with
investigating or defending any such action or claim. Notwithstanding this Section 6(d), no indemnifying party that is a selling Holder shall be required to contribute any 
  

 19 

 amount in excess of the amount by which the total price at which the Registrable Securities sold by it and distributed to
the public were offered to the public exceeds the amount of any damages that such indemnifying party has otherwise been required to pay by reason of such untrue or alleged untrue statement or omission or alleged omission. No person guilty of
fraudulent misrepresentation (within the meaning of Section 11(f) of the Securities Act) shall be entitled to contribution from any person who was not guilty of such fraudulent misrepresentation. 
 (e) The remedies provided for in this Section 6 are not exclusive and shall not limit any rights or remedies which may otherwise be available to an
indemnified party at law or in equity, hereunder, under the Purchase Agreement or otherwise. 
 (f) The indemnity and contribution provisions
contained in this Section 6 shall remain operative and in full force and effect regardless of (i) any termination of this Agreement, (ii) any investigation made by or on behalf of any Holder, any person controlling any Holder or any
affiliate of any Holder or by or on behalf of the Company, its officers or directors or any person controlling the Company and (iii) the sale of any Registrable Securities by any Holder. 
 Section 7. Information Requirements. The Company covenants that, if at any time before the end of the Effectiveness Period, the Company is
not subject to the reporting requirements of the Exchange Act, it will cooperate with any Holder and take such further reasonable action as any Holder may reasonably request in writing (including, without limitation, making such reasonable
representations as any such Holder may reasonably request), all to the extent required from time to time to enable such Holder to sell Registrable Securities without registration under the Securities Act within the limitation of the exemptions
provided by Rule 144 and Rule 144A under the Securities Act and customarily taken in connection with sales pursuant to such exemptions. Upon the written request of any Holder, the Company shall deliver to such Holder a written statement as to
whether it has complied with such filing requirements, unless such a statement has been included in the Company’s most recent report filed pursuant to Section 13 or Section 15(d) of Exchange Act. Notwithstanding the foregoing, nothing
in this Section 7 shall be deemed to require the Company to register any of its securities (other than the Common Stock) under the Exchange Act. 
 Section 8. Miscellaneous. 
 (a) No Conflicting Agreements. The Company is not, as of the
date hereof, a party to, nor shall it, on or after the date of this Agreement, enter into, any agreement with respect to its securities that conflicts with the rights granted to the Holders in this Agreement. The Company represents and warrants that
the rights granted to the Holders hereunder do not in any way conflict with the rights granted to the holders of the Company’s securities under any other agreements. 
  

 20 

 (b) Amendments and Waivers. The provisions of this Agreement, including the provisions of this
sentence, may not be amended, modified or supplemented, and waivers or consents to departures from the provisions hereof may not be given, unless the Company has obtained the written consent of Holders of a majority of the then outstanding
Underlying Common Stock constituting Registrable Securities (with Holders of Securities deemed to be the Holders, for purposes of this Section, of the number of outstanding shares of Underlying Common Stock into which such Securities are or would be
convertible as of the date on which such consent is requested). Notwithstanding the foregoing, a waiver or consent to depart from the provisions hereof with respect to a matter that relates exclusively to the rights of Holders whose securities are
being sold pursuant to a Shelf Registration Statement and that does not directly or indirectly affect the rights of other Holders may be given by Holders of at least a majority of the Registrable Securities being sold by such Holders pursuant to
such Shelf Registration Statement; provided that the provisions of this sentence may not be amended, modified or supplemented except in accordance with the provisions of the immediately preceding sentence. Notwithstanding the foregoing
sentence, this Agreement may be amended by written agreement signed by the Company and the Initial Purchasers, without the consent of the Holders of Registrable Securities, to cure any ambiguity or to correct or supplement any provision contained
herein that may be defective or inconsistent with any other provision contained herein, or to make such other provisions in regard to matters or questions arising under this Agreement that shall not adversely affect the interests of the Holders of
Registrable Securities. Each Holder of Registrable Securities outstanding at the time of any such amendment, modification, supplement, waiver or consent or thereafter shall be bound by any such amendment, modification, supplement, waiver or consent
effected pursuant to this Section 8(b) whether or not any notice, writing or marking indicating such amendment, modification, supplement, waiver or consent appears on the Registrable Securities or is delivered to such Holder. 
 (c) Notices. All notices and other communications provided for or permitted hereunder shall be made in writing by hand delivery, by fax, by
courier or by first-class mail, return receipt requested, and shall be deemed given (i) when made, if made by hand delivery, (ii) upon confirmation, if made by telecopier, (iii) one Business Day after being deposited with such
courier, if made by overnight courier or (iv) on the date indicated on the notice of receipt, if made by first-class mail, to the parties as follows: 
 (i) if to a Holder, at the most current address given by such Holder to the Company in a Notice and Questionnaire or any amendment thereto; 
 (ii) if to the Company, to: 
 Beckman Coulter, Inc. 
 4300 N. Harbor Boulevard 
 Fullerton, California 92834 
 Attention: General Counsel 
 Fax: (714) 773-8543 
  

 21 

 with a copy to: 
 Latham & Watkins LLP 
 633 West Fifth Street, Suite 4000 
 Los Angeles, California 90071 
 Attention:
Cynthia Rotell 
 Fax: (213) 891-8763 
 (iii) if to the Initial Purchasers, to: 
 Morgan Stanley & Co. Incorporated 
 1585 Broadway 
 New York, New York 10036

 Attention: Convertible Debt Syndicate Desk 
 Fax: (212) 761-0538 
 with copies to: 
 Davis Polk & Wardwell 
 1600 El
Camino Real 
 Menlo Park, California 94025 
 Attention: Bruce K. Dallas 
 Fax: (650) 752-2111 
 or to such other address as such person may have furnished to the other persons identified in this Section 8(c) in writing in accordance herewith. 
 (d) Approval of Holders. Whenever the consent or approval of Holders of a specified percentage of Registrable Securities is required hereunder,
Registrable Securities held by the Company or its affiliates (as such term is defined in Rule 405 under the Securities Act) (other than the Initial Purchasers or subsequent Holders if such subsequent Holders are deemed to be such affiliates solely
by reason of their holdings of such Registrable Securities) shall not be counted in determining whether such consent or approval was given by the Holders of such required percentage. 
 (e) Successors and Assigns. Any person who purchases any Registrable Securities from the Initial Purchasers shall be deemed, for purposes of this
Agreement, to be an assignee of the Initial Purchasers. This Agreement shall inure to the benefit of and be binding upon the successors and assigns of each of the parties and shall inure to the benefit of and be binding upon each Holder of any
Registrable Securities, provided that nothing herein shall be deemed to permit any assignment, transfer or other disposition of Registrable Securities in violation 
  

 22 

 of the terms of the Indenture. If any transferee of any Holder shall acquire Registrable Securities, in any manner,
whether by operation of law or otherwise, such Registrable Securities shall be held subject to all of the terms of this Agreement, and by taking and holding such Registrable Securities, such person shall be conclusively deemed to have agreed to be
bound by and to perform all of the terms and provisions of this Agreement and such person shall be entitled to receive the benefits hereof. 
 (f) Counterparts. This Agreement may be executed in any number of counterparts and by the parties hereto in separate counterparts, each of which when so executed shall be deemed to be original and all of which taken together shall
constitute one and the same agreement. 
 (g) Headings. The headings in this Agreement are for convenience of reference only and shall
not limit or otherwise affect the meaning hereof. 
 (h) Governing Law. THIS AGREEMENT SHALL BE GOVERNED BY AND CONSTRUED IN
ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK. 
 (i) Severability. If any term, provision, covenant or restriction of this
Agreement is held to be invalid, illegal, void or unenforceable, the remainder of the terms, provisions, covenants and restrictions set forth herein shall remain in full force and effect and shall in no way be affected, impaired or invalidated
thereby, and the parties hereto shall use their best efforts to find and employ an alternative means to achieve the same or substantially the same result as that contemplated by such term, provision, covenant or restriction, it being intended that
all of the rights and privileges of the parties shall be enforceable to the fullest extent permitted by law. 
 (j) Entire Agreement.
This Agreement is intended by the parties as a final expression of their agreement and is intended to be a complete and exclusive statement of the agreement and understanding of the parties hereto in respect of the subject matter contained herein
and the registration rights granted by the Company with respect to the Registrable Securities. Except as provided in the Purchase Agreement, there are no restrictions, promises, warranties or undertakings, other than those set forth or referred to
herein, with respect to the registration rights granted by the Company with respect to the Registrable Securities. This Agreement supersedes all prior agreements and undertakings among the parties with respect to such registration rights. No party
hereto shall have any rights, duties or obligations other than those specifically set forth in this Agreement. In no event will such methods of distribution take the form of an underwritten offering of the Registrable Securities without the prior
agreement of the Company. 
 (k) Termination. This Agreement and the obligations of the parties hereunder shall terminate upon the end
of the Effectiveness Period, except for any liabilities or obligations under Section 4, 5 or 6 hereof and the obligations to make payments of and provide for Additional Interest under Section 2(f) hereof to the extent such Additional
Interest accrues prior to the end of the Effectiveness Period, each of which shall remain in effect in accordance with its terms. 
  

 23 

 IN WITNESS WHEREOF, the parties have executed this Agreement as of the date first written above.

  

			
	BECKMAN COULTER, INC.
		
	By:	 	 /s/ Arnold Pinkston

	Name:	 	Arnold Pinkston
	Title:	 	Senior Vice President and General Counsel

 Confirmed and accepted as of 
 the date first above written, for itself 
 and as representative of the several Initial Purchasers: 
  

			
	MORGAN STANLEY & CO. INCORPORATED
		
	By:	 	 /s/ Bryan W. Andrzejewski

	Name:	 	Bryan W. Andrzejewski
	Title:	 	Executive Director

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