Document:

Exhibit 10.2

 

 

REGISTRATION RIGHTS AGREEMENT

 

This Registration Rights
Agreement (this “Agreement”) is made and entered into as of January 21, 2021, between Synaptogenix, Inc., a
Delaware corporation (the “Company”), and each of the several purchasers signatory hereto (each such purchaser,
a “Purchaser” and, collectively, the “Purchasers”).

 

This Agreement is
made pursuant to the Securities Purchase Agreement, dated as of the date hereof, between the Company and each Purchaser (the “Purchase
Agreement”).

 

The Company and each
Purchaser hereby agrees as follows:

 

1.        Definitions.

 

Capitalized terms
used and not otherwise defined herein that are defined in the Purchase Agreement shall have the meanings given such terms in the
Purchase Agreement. As used in this Agreement, the following terms shall have the following meanings:

 

“Advice”
shall have the meaning set forth in Section 6(d).

 

“Effectiveness
Date” means, with respect to the Initial Registration Statement required to be filed hereunder, the 120th
calendar day following the date hereof (or, in the event of a “full review” by the Commission, the 150th
calendar day following the date hereof) and with respect to any additional Registration Statements which may be required pursuant
to Section 2(c) or Section 3(c), the 120th calendar day following the date on which an additional Registration Statement
is required to be filed hereunder (or, in the event of a “full review” by the Commission, the 150th calendar
day following the date such additional Registration Statement is required to be filed hereunder); provided, however,
that in the event the Company is notified by the Commission that one or more of the above Registration Statements will not be reviewed
or is no longer subject to further review and comments, the Effectiveness Date as to such Registration Statement shall be the fifth
Trading Day following the date on which the Company is so notified if such date precedes the dates otherwise required above, provided,
further, if such Effectiveness Date falls on a day that is not a Trading Day, then the Effectiveness Date shall be the next succeeding
Trading Day.

 

“Effectiveness
Period” shall have the meaning set forth in Section 2(a).

 

“Event”
shall have the meaning set forth in Section 2(d).

 

“Event
Date” shall have the meaning set forth in Section 2(d).

 

“Filing
Date” means, with respect to the Initial Registration Statement required hereunder, the 30th calendar day
following the date hereof and, with respect to any additional Registration Statements which may be required pursuant to Section
2(c) or Section 3(c), the earliest practical date on which the Company is permitted by SEC Guidance to file such additional Registration
Statement related to the Registrable Securities.

 

     

     

    

 

“Holder”
or “Holders” means the holder or holders, as the case may be, from time to time of Registrable Securities.

 

“Indemnified
Party” shall have the meaning set forth in Section 5(c).

 

“Indemnifying
Party” shall have the meaning set forth in Section 5(c).

 

“Initial
Registration Statement” means the initial Registration Statement filed pursuant to this Agreement.

 

“Losses”
shall have the meaning set forth in Section 5(a).

 

“Plan
of Distribution” shall have the meaning set forth in Section 2(a).

 

“Prospectus”
means the prospectus included in a Registration Statement (including, without limitation, a prospectus that includes any information
previously omitted from a prospectus filed as part of an effective registration statement in reliance upon Rule 430A promulgated
by the Commission pursuant to the Securities Act), as amended or supplemented by any prospectus supplement, with respect to the
terms of the offering of any portion of the Registrable Securities covered by a Registration Statement, and all other amendments
and supplements to the Prospectus, including post-effective amendments, and all material incorporated by reference or deemed to
be incorporated by reference in such Prospectus.

 

“Registrable
Securities” means, as of any date of determination, (a) all shares of Common Stock issued pursuant to the Purchase Agreement,
(b) all Warrant Shares then issued and issuable upon exercise of the Warrants (assuming on such date the Warrants are exercised
in full without regard to any exercise limitations therein), (c) all Pre-Funded Warrant Shares then issued and issuable upon exercise
of the Pre-Funded Warrants (assuming on such date the Pre-Funded Warrants are exercised in full without regard to any exercise
limitations therein) and (d) any securities issued or then issuable upon any stock split, dividend or other distribution, recapitalization
or similar event with respect to the foregoing; provided, however, that any such Registrable Securities shall cease to be
Registrable Securities (and the Company shall not be required to maintain the effectiveness of any, or file another, Registration
Statement hereunder with respect thereto) for so long as (a) a Registration Statement with respect to the sale of such Registrable
Securities is declared effective by the Commission under the Securities Act and such Registrable Securities have been disposed
of by the Holder in accordance with such effective Registration Statement, (b) such Registrable Securities have been previously
sold in accordance with Rule 144, or (c) such securities become eligible for resale without volume or manner-of-sale restrictions
and without current public information pursuant to Rule 144 as set forth in a written opinion letter to such effect, addressed,
delivered and acceptable to the Transfer Agent and the affected Holders (assuming that such securities and any securities issuable
upon exercise, conversion or exchange of which, or as a dividend upon which, such securities were issued or are issuable, were
at no time held by any Affiliate of the Company, and all Warrants and Pre-Funded Warrants are exercised by “cashless exercise”
as provided in Section 2(c) of each of the Warrants and Pre-Funded Warrants, as applicable), as reasonably determined by the Company,
upon the advice of counsel to the Company.

 

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“Registration
Statement” means any registration statement required to be filed hereunder pursuant to Section 2(a) and any additional
registration statements contemplated by Section 2(c) or Section 3(c), including (in each case) the Prospectus, amendments and supplements
to any such registration statement or Prospectus, including pre- and post-effective amendments, all exhibits thereto, and all material
incorporated by reference or deemed to be incorporated by reference in any such registration statement.

 

“Rule
415” means Rule 415 promulgated by the Commission pursuant to the Securities Act, as such Rule may be amended or interpreted
from time to time, or any similar rule or regulation hereafter adopted by the Commission having substantially the same purpose
and effect as such Rule.

 

“Rule
424” means Rule 424 promulgated by the Commission pursuant to the Securities Act, as such Rule may be amended or interpreted
from time to time, or any similar rule or regulation hereafter adopted by the Commission having substantially the same purpose
and effect as such Rule.

 

“Selling
Stockholder Questionnaire” shall have the meaning set forth in Section 3(a).

 

“SEC
Guidance” means (i) any publicly-available written or oral guidance of the Commission staff, or any comments, requirements
or requests of the Commission staff and (ii) the Securities Act.

 

2.        Registration.

 

(a)              
On or prior to each Filing Date, the Company shall prepare and file with the Commission a Registration Statement covering
the resale of all of the Registrable Securities that are not then registered on an effective Registration Statement for an offering
to be made on a continuous basis pursuant to Rule 415. Each Registration Statement filed hereunder shall be on Form S-1 and shall
contain (unless otherwise directed by at least 85% in interest of the Holders) substantially the “Plan of Distribution”
attached hereto as Annex A and substantially the “Selling Stockholder” section attached hereto as Annex
B; provided, however, that no Holder shall be required to be named as an “underwriter” without such
Holder’s express prior written consent. Subject to the terms of this Agreement, the Company shall use its best efforts to
cause a Registration Statement filed under this Agreement (including, without limitation, under Section 3(c)) to be declared effective
under the Securities Act as promptly as possible after the filing thereof, but in any event no later than the applicable Effectiveness
Date, and shall use its best efforts to keep such Registration Statement continuously effective under the Securities Act until
the date that all Registrable Securities covered by such Registration Statement (i) have been sold, thereunder or pursuant to Rule
144, or (ii) may be sold without volume or manner-of-sale restrictions pursuant to Rule 144 and without the requirement for the
Company to be in compliance with the current public information requirement under Rule 144, as determined by the counsel to the
Company pursuant to a written opinion letter to such effect, addressed and acceptable to the Transfer Agent and the affected Holders
(the “Effectiveness Period”). The Company shall telephonically request effectiveness of a Registration Statement
as of 5:00 p.m. Eastern Time on a Trading Day. The Company shall immediately notify the Holders via facsimile or by e-mail of the
effectiveness of a Registration Statement on the same Trading Day that the Company telephonically confirms effectiveness with the
Commission, which shall be the date requested for effectiveness of such Registration Statement. The Company shall, by 9:30 a.m.
Eastern Time on the Trading Day after the effective date of such Registration Statement, file a final Prospectus with the Commission
as required by Rule 424. Failure to so notify the Holder within one (1) Trading Day of such notification of effectiveness or failure
to file a final Prospectus as foresaid shall be deemed an Event under Section 2(d).

 

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(b)              
 Notwithstanding the registration obligations set forth in Section 2(a), if the Commission informs the Company that all
of the Registrable Securities cannot, as a result of the application of Rule 415, be registered for resale as a secondary offering
on a single registration statement, the Company agrees to promptly inform each of the Holders thereof and use its commercially
reasonable efforts to file amendments to the Initial Registration Statement as required by the Commission, covering the maximum
number of Registrable Securities permitted to be registered by the Commission.

 

(c)              
Notwithstanding any other provision of this Agreement and subject to the payment of liquidated damages pursuant to Section
2(d), if the Commission or any SEC Guidance sets forth a limitation on the number of Registrable Securities permitted to be registered
on a particular Registration Statement as a secondary offering, unless otherwise directed in writing
by a Holder as to its Registrable Securities, the number of Registrable Securities to be registered on such Registration Statement
will be reduced as follows: 

 

		a.	First,
                                         the Company shall reduce or eliminate any securities to be included other than Registrable
                                         Securities;

 

 

 

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		b.	Second,
                                         the Company shall reduce Registrable Securities represented by Warrant Shares (applied,
                                         in the case that some Warrant Shares may be registered, to the Holders on a pro rata
                                         basis based on the total number of unregistered Warrant Shares held by such Holders);
                                         and 

 

		c.	Third,
                                         the Company shall reduce Registrable Securities represented by Pre-Funded Warrant Shares
                                         (applied, in the case that some Pre-Funded Warrant Shares may be registered, to the Holders
                                         on a pro rata basis based on the total number of unregistered Pre-Funded Warrant Shares
                                         held by such Holders). 

 

In
the event of a cutback hereunder, the Company shall give the Holder at least five (5) Trading Days prior written notice along
with the calculations as to such Holder’s allotment. In the event the Company amends the Initial Registration Statement
in accordance with the foregoing, the Company will use its best efforts to file with the Commission, as promptly as allowed by
Commission or SEC Guidance provided to the Company or to registrants of securities in general, one or more registration statements
to register for resale those Registrable Securities that were not registered for resale on the Initial Registration Statement,
as amended.

 

(d)              
If: (i) the Initial Registration Statement is not filed on or prior to its Filing Date (if the Company files the Initial
Registration Statement without affording the Holders the opportunity to review and comment on the same as required by Section 3(a)
herein, the Company shall be deemed to have not satisfied this clause (i)), or (ii) the Company fails to file with the Commission
a request for acceleration of a Registration Statement in accordance with Rule 461 promulgated by the Commission pursuant to the
Securities Act, within five Trading Days of the date that the Company is notified (orally or in writing, whichever is earlier)
by the Commission that such Registration Statement will not be “reviewed” or will not be subject to further review,
or (iii) prior to the effective date of a Registration Statement, the Company fails to file a pre-effective amendment and otherwise
respond in writing to comments made by the Commission in respect of such Registration Statement within ten (10) calendar days after
the receipt of comments by or notice from the Commission that such amendment is required in order for such Registration Statement
to be declared effective, or (iv) a Registration Statement registering for resale all of the Registrable Securities is not declared
effective by the Commission by the Effectiveness Date of the Initial Registration Statement, or (v) after the effective date of
a Registration Statement, such Registration Statement ceases for any reason to remain continuously effective as to all Registrable
Securities included in such Registration Statement, or the Holders are otherwise not permitted to utilize the Prospectus therein
to resell such Registrable Securities, for more than ten (10) consecutive calendar days or more than an aggregate of fifteen (15)
calendar days (which need not be consecutive calendar days) during any 12-month period (any such failure or breach being referred
to as an “Event”, and for purposes of clauses (i) and (iv), the date on which such Event occurs, and for purpose
of clause (ii) the date on which such five (5) Trading Day period is exceeded, and for purpose of clause (iii) the date which such
ten (10) calendar day period is exceeded, and for purpose of clause (v) the date on which such ten (10) or fifteen (15) calendar
day period, as applicable, is exceeded being referred to as “Event Date”), then, in addition to any other rights
the Holders may have hereunder or under applicable law, on each such Event Date and on each monthly anniversary of each such Event
Date (if the applicable Event shall not have been cured by such date) until the applicable Event is cured, the Company shall pay
to each Holder an amount in cash, as partial liquidated damages and not as a penalty, equal to the product of 2.0% multiplied by
the aggregate Subscription Amount paid by such Holder pursuant to the Purchase Agreement The parties agree that the maximum aggregate
liquidated damages payable to a Holder under this Agreement shall be 12.0% of the aggregate Subscription Amount paid by such Holder
pursuant to the Purchase Agreement. If the Company fails to pay any partial liquidated damages pursuant to this Section in full
within seven days after the date payable, the Company will pay interest thereon at a rate of 18% per annum (or such lesser maximum
amount that is permitted to be paid by applicable law) to the Holder, accruing daily from the date such partial liquidated damages
are due until such amounts, plus all such interest thereon, are paid in full. The partial liquidated damages pursuant to the terms
hereof shall apply on a daily pro rata basis for any portion of a month prior to the cure of an Event.

 

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(e)              
Notwithstanding anything to the contrary contained herein, in no event shall the Company be permitted to name any Holder
or affiliate of a Holder as any Underwriter without the prior written consent of such Holder.

 

3.        Registration
Procedures.

 

In connection with
the Company’s registration obligations hereunder, the Company shall:

 

(a)              
Not less than five (5) Trading Days prior to the filing of each Registration Statement and not less than one (1) Trading
Day prior to the filing of any related Prospectus or any amendment or supplement thereto (including any document that would be
incorporated or deemed to be incorporated therein by reference), the Company shall (i) furnish to each Holder copies of all such
documents proposed to be filed, which documents (other than those incorporated or deemed to be incorporated by reference) will
be subject to the review of such Holders, and (ii) cause its officers and directors, counsel and independent registered public
accountants to respond to such inquiries as shall be necessary, in the reasonable opinion of respective counsel to each Holder,
to conduct a reasonable investigation within the meaning of the Securities Act. The Company shall not file a Registration Statement
or any such Prospectus or any amendments or supplements thereto to which the Holders of a majority of the Registrable Securities
shall reasonably object in good faith, provided that, the Company is notified of such objection in writing no later than five (5)
Trading Days after the Holders have been so furnished copies of a Registration Statement or one (1) Trading Day after the Holders
have been so furnished copies of any related Prospectus or amendments or supplements thereto. Each Holder agrees to furnish to
the Company a completed questionnaire in the form attached to this Agreement as Annex B (a “Selling Stockholder
Questionnaire”) on a date that is not less than two (2) Trading Days prior to the Filing Date or by the end of the fourth
(4th) Trading Day following the date on which such Holder receives draft materials in accordance with this Section.

 

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(b)              
(i) Prepare and file with the Commission such amendments, including post-effective amendments, to a Registration Statement
and the Prospectus used in connection therewith as may be necessary to keep a Registration Statement continuously effective as
to the applicable Registrable Securities for the Effectiveness Period and prepare and file with the Commission such additional
Registration Statements in order to register for resale under the Securities Act all of the Registrable Securities, (ii) cause
the related Prospectus to be amended or supplemented by any required Prospectus supplement (subject to the terms of this Agreement),
and, as so supplemented or amended, to be filed pursuant to Rule 424, (iii) respond as promptly as reasonably possible to any comments
received from the Commission with respect to a Registration Statement or any amendment thereto and provide as promptly as reasonably
possible to the Holders true and complete copies of all correspondence from and to the Commission relating to a Registration Statement
(provided that, the Company shall excise any information contained therein which would constitute material non-public information
regarding the Company or any of its Subsidiaries), and (iv) comply in all material respects with the applicable provisions of the
Securities Act and the Exchange Act with respect to the disposition of all Registrable Securities covered by a Registration Statement
during the applicable period in accordance (subject to the terms of this Agreement) with the intended methods of disposition by
the Holders thereof set forth in such Registration Statement as so amended or in such Prospectus as so supplemented.

 

(c)              
If during the Effectiveness Period, the number of Registrable Securities at any time exceeds 100% of the number of shares
of Common Stock then registered in a Registration Statement, then the Company shall file as soon as reasonably practicable, but
in any case prior to the applicable Filing Date, an additional Registration Statement covering the resale by the Holders of not
less than the number of such Registrable Securities.

 

(d)              
Notify the Holders of Registrable Securities to be sold (which notice shall, pursuant to clauses (iii) through (vi) hereof,
be accompanied by an instruction to suspend the use of the Prospectus until the requisite changes have been made) as promptly as
reasonably possible (and, in the case of (i)(A) below, not less than one (1) Trading Day prior to such filing) and (if requested
by any such Person) confirm such notice in writing no later than one (1) Trading Day following the day (i)(A) when a Prospectus
or any Prospectus supplement or post-effective amendment to a Registration Statement is proposed to be filed, (B) when the Commission
notifies the Company whether there will be a “review” of such Registration Statement and whenever the Commission comments
in writing on such Registration Statement, and (C) with respect to a Registration Statement or any post-effective amendment, when
the same has become effective, (ii) of any request by the Commission or any other federal or state governmental authority for amendments
or supplements to a Registration Statement or Prospectus or for additional information, (iii) of the issuance by the Commission
or any other federal or state governmental authority of any stop order suspending the effectiveness of a Registration Statement
covering any or all of the Registrable Securities or the initiation of any Proceedings for that purpose, (iv) of the receipt by
the Company of any notification with respect to the suspension of the qualification or exemption from qualification of any of the
Registrable Securities for sale in any jurisdiction, or the initiation or threatening of any Proceeding for such purpose, (v) of
the occurrence of any event or passage of time that makes the financial statements included in a Registration Statement ineligible
for inclusion therein or any statement made in a Registration Statement or Prospectus or any document incorporated or deemed to
be incorporated therein by reference untrue in any material respect or that requires any revisions to a Registration Statement,
Prospectus or other documents so that, in the case of a Registration Statement or the Prospectus, as the case may be, it will not
contain any untrue statement of a material fact or omit to state any material fact required to be stated therein or necessary to
make the statements therein, in light of the circumstances under which they were made, not misleading, and (vi) of the occurrence
or existence of any pending corporate development with respect to the Company that the Company believes may be material and that,
in the determination of the Company, makes it not in the best interest of the Company to allow continued availability of a Registration
Statement or Prospectus, provided, however, in no event shall any such notice contain any information which would
constitute material, non-public information regarding the Company or any of its Subsidiaries.

 

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(e)              
Use its best efforts to avoid the issuance of, or, if issued, obtain the withdrawal of (i) any order stopping or suspending
the effectiveness of a Registration Statement, or (ii) any suspension of the qualification (or exemption from qualification) of
any of the Registrable Securities for sale in any jurisdiction, at the earliest practicable moment.

 

(f)               
Furnish to each Holder, without charge, at least one conformed copy of each such Registration Statement and each amendment
thereto, including financial statements and schedules, all documents incorporated or deemed to be incorporated therein by reference
to the extent requested by such Person, and all exhibits to the extent requested by such Person (including those previously furnished
or incorporated by reference) promptly after the filing of such documents with the Commission; provided, that any such item which
is available on the EDGAR system (or successor thereto) need not be furnished in physical form.

 

(g)              
Subject to the terms of this Agreement, the Company hereby consents to the use of such Prospectus and each amendment or
supplement thereto by each of the selling Holders in connection with the offering and sale of the Registrable Securities covered
by such Prospectus and any amendment or supplement thereto, except after the giving of any notice pursuant to Section 3(d).

 

(h)              
 Prior to any resale of Registrable Securities by a Holder, use its commercially reasonable efforts to register or qualify
or cooperate with the selling Holders in connection with the registration or qualification (or exemption from the Registration
or qualification) of such Registrable Securities for the resale by the Holder under the securities or Blue Sky laws of such jurisdictions
within the United States as any Holder reasonably requests in writing, to keep each registration or qualification (or exemption
therefrom) effective during the Effectiveness Period and to do any and all other acts or things reasonably necessary to enable
the disposition in such jurisdictions of the Registrable Securities covered by each Registration Statement; provided, that, the
Company shall not be required to qualify generally to do business in any jurisdiction where it is not then so qualified, subject
the Company to any material tax in any such jurisdiction where it is not then so subject or file a general consent to service of
process in any such jurisdiction.

 

(i)                
If requested by a Holder, cooperate with such Holder to facilitate the timely preparation and delivery of certificates representing
Registrable Securities to be delivered to a transferee pursuant to a Registration Statement, which certificates shall be free,
to the extent permitted by the Purchase Agreement, of all restrictive legends, and to enable such Registrable Securities to be
in such denominations and registered in such names as any such Holder may request.

 

(j)                
Upon the occurrence of any event contemplated by Section 3(d), as promptly as reasonably possible under the circumstances
taking into account the Company’s good faith assessment of any adverse consequences to the Company and its stockholders of
the premature disclosure of such event, prepare a supplement or amendment, including a post-effective amendment, to a Registration
Statement or a supplement to the related Prospectus or any document incorporated or deemed to be incorporated therein by reference,
and file any other required document so that, as thereafter delivered, neither a Registration Statement nor such Prospectus will
contain an untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make
the statements therein, in light of the circumstances under which they were made, not misleading. If
the Company notifies the Holders in accordance with clauses (iii) through (vi) of Section 3(d) above to suspend the use of any
Prospectus until the requisite changes to such Prospectus have been made, then the Holders shall suspend use of such Prospectus.
The Company will use its best efforts to ensure that the use of the Prospectus may be resumed as promptly as is practicable. The
Company shall be entitled to exercise its right under this Section 3(j) to suspend the availability of a Registration Statement
and Prospectus, subject to the payment of partial liquidated damages otherwise required pursuant to Section 2(d), for a period
not to exceed 60 calendar days (which need not be consecutive days) in any 12-month period.

 

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(k)              
Otherwise use commercially reasonable efforts to comply with all applicable rules and regulations of the Commission under
the Securities Act and the Exchange Act, including, without limitation, Rule 172 under the Securities Act, file any final Prospectus,
including any supplement or amendment thereof, with the Commission pursuant to Rule 424 under the Securities Act, promptly inform
the Holders in writing if, at any time during the Effectiveness Period, the Company does not satisfy the conditions specified in
Rule 172 and, as a result thereof, the Holders are required to deliver a Prospectus in connection with any disposition of Registrable
Securities and take such other actions as may be reasonably necessary to facilitate the registration of the Registrable Securities
hereunder.

 

(l)                
The Company may require each selling Holder to furnish to the Company a certified statement as to the number of shares of
Common Stock beneficially owned by such Holder and, if required by the Commission, the natural persons thereof that have voting
and dispositive control over the shares. During any periods that the Company is unable to meet its obligations hereunder with respect
to the registration of the Registrable Securities solely because any Holder fails to furnish such information within three Trading
Days of the Company’s request, any liquidated damages that are accruing at such time as to such Holder only shall be tolled
and any Event that may otherwise occur solely because of such delay shall be suspended as to such Holder only, until such information
is delivered to the Company.

 

4.        Registration
Expenses. All fees and expenses incident to the performance of or compliance with, this Agreement by the Company shall be borne
by the Company whether or not any Registrable Securities are sold pursuant to a Registration Statement. The fees and expenses referred
to in the foregoing sentence shall include, without limitation, (i) all registration and filing fees (including, without limitation,
fees and expenses of the Company’s counsel and independent registered public accountants) (A) with respect to filings made
with the Commission, (B) with respect to filings required to be made with any Trading Market on which the Common Stock is then
listed for trading, and (C) in compliance with applicable state securities or Blue Sky laws reasonably agreed to by the Company
in writing (including, without limitation, fees and disbursements of counsel for the Company in connection with Blue Sky qualifications
or exemptions of the Registrable Securities), (ii) printing expenses (including, without limitation, expenses of printing certificates
for Registrable Securities), (iii) messenger, telephone and delivery expenses, (iv) fees and disbursements of counsel for the Company,
(v) Securities Act liability insurance, if the Company so desires such insurance, and (vi) fees and expenses of all other Persons
retained by the Company in connection with the consummation of the transactions contemplated by this Agreement. In addition, the
Company shall be responsible for all of its internal expenses incurred in connection with the consummation of the transactions
contemplated by this Agreement (including, without limitation, all salaries and expenses of its officers and employees performing
legal or accounting duties), the expense of any annual audit and the fees and expenses incurred in connection with the listing
of the Registrable Securities on any securities exchange as required hereunder. In no event shall the Company be responsible for
any broker or similar commissions of any Holder or, except to the extent provided for in the Transaction Documents, any legal fees
or other costs of the Holders.

 

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5.        Indemnification.

 

(a)              
Indemnification by the Company. The Company shall, notwithstanding any termination of this Agreement, indemnify and
hold harmless each Holder, the officers, directors, members, partners, agents, brokers (including brokers who offer and sell Registrable
Securities as principal as a result of a pledge or any failure to perform under a margin call of Common Stock), investment advisors
and employees (and any other Persons with a functionally equivalent role of a Person holding such titles, notwithstanding a lack
of such title or any other title) of each of them, each Person who controls any such Holder (within the meaning of Section 15 of
the Securities Act or Section 20 of the Exchange Act) and the officers, directors, members, stockholders, partners, agents and
employees (and any other Persons with a functionally equivalent role of a Person holding such titles, notwithstanding a lack of
such title or any other title) of each such controlling Person, to the fullest extent permitted by applicable law, from and against
any and all losses, claims, damages, liabilities, costs (including, without limitation, reasonable attorneys’ fees) and expenses
(collectively, “Losses”), as incurred, arising out of or relating to (1) any untrue or alleged untrue statement
of a material fact contained in a Registration Statement, any Prospectus or any form of prospectus or in any amendment or supplement
thereto or in any preliminary prospectus, or arising out of or relating to any omission or alleged omission of a material fact
required to be stated therein or necessary to make the statements therein (in the case of any Prospectus or supplement thereto,
in light of the circumstances under which they were made) not misleading or (2) any violation or alleged violation by the Company
of the Securities Act, the Exchange Act or any state securities law, or any rule or regulation thereunder, in connection with the
performance of its obligations under this Agreement, except to the extent, but only to the extent, that (i) such untrue statements
or omissions are based solely upon information regarding such Holder furnished in writing to the Company by such Holder expressly
for use therein, or to the extent that such information relates to such Holder or such Holder’s proposed method of distribution
of Registrable Securities and was reviewed and expressly approved in writing by such Holder expressly for use in a Registration
Statement, such Prospectus or in any amendment or supplement thereto (it being understood that the Holder has approved Annex A
hereto for this purpose) or (ii) in the case of an occurrence of an event of the type specified in Section 3(d)(iii)-(vi), the
use by such Holder of an outdated, defective or otherwise unavailable Prospectus after the Company has notified such Holder in
writing that the Prospectus is outdated, defective or otherwise unavailable for use by such Holder and prior to the receipt by
such Holder of the Advice contemplated in Section 6(d). The Company shall notify the Holders promptly of the institution, threat
or assertion of any Proceeding arising from or in connection with the transactions contemplated by this Agreement of which the
Company is aware. Such indemnity shall remain in full force and effect regardless of any investigation made by or on behalf of
such indemnified person and shall survive the transfer of any Registrable Securities by any of the Holders in accordance with Section
6(h).

 

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(b)              
Indemnification by Holders. Each Holder shall, severally and not jointly, indemnify and hold harmless the Company,
its directors, officers, agents and employees, each Person who controls the Company (within the meaning of Section 15 of the Securities
Act and Section 20 of the Exchange Act), and the directors, officers, agents or employees of such controlling Persons, to the fullest
extent permitted by applicable law, from and against all Losses, as incurred, to the extent arising out of or based solely upon:
any untrue or alleged untrue statement of a material fact contained in any Registration Statement, any Prospectus, or in any amendment
or supplement thereto or in any preliminary prospectus, or arising out of or relating to any omission or alleged omission of a
material fact required to be stated therein or necessary to make the statements therein (in the case of any Prospectus or supplement
thereto, in light of the circumstances under which they were made) not misleading (i) to the extent, but only to the extent, that
such untrue statement or omission is contained in any information so furnished in writing by such Holder to the Company expressly
for inclusion in such Registration Statement or such Prospectus or (ii) to the extent, but only to the extent, that such information
relates to such Holder’s information provided in the Selling Stockholder Questionnaire or the proposed method of distribution
of Registrable Securities and was reviewed and expressly approved in writing by such Holder expressly for use in a Registration
Statement (it being understood that the Holder has approved Annex A hereto for this purpose), such Prospectus or in any amendment
or supplement thereto. In no event shall the liability of a selling Holder be greater in amount than the dollar amount of the proceeds
(net of all expenses paid by such Holder in connection with any claim relating to this Section 5 and the amount of any damages
such Holder has otherwise been required to pay by reason of such untrue statement or omission) received by such Holder upon the
sale of the Registrable Securities included in the Registration Statement giving rise to such indemnification obligation.

 

(c)              
Conduct of Indemnification Proceedings. If any Proceeding shall be brought or asserted against any Person entitled
to indemnity hereunder (an “Indemnified Party”), such Indemnified Party shall promptly notify the Person from
whom indemnity is sought (the “Indemnifying Party”) in writing, and the Indemnifying Party shall have the right
to assume the defense thereof, including the employment of counsel reasonably satisfactory to the Indemnified Party and the payment
of all fees and expenses incurred in connection with defense thereof; provided, that, the failure of any Indemnified Party to give
such notice shall not relieve the Indemnifying Party of its obligations or liabilities pursuant to this Agreement, except (and
only) to the extent that it shall be finally determined by a court of competent jurisdiction (which determination is not subject
to appeal or further review) that such failure shall have materially and adversely prejudiced the Indemnifying Party.

 

    	 	11	 

     

    

 

An Indemnified
Party shall have the right to employ separate counsel in any such Proceeding and to participate in the defense thereof, but the
fees and expenses of such counsel shall be at the expense of such Indemnified Party or Parties unless: (1) the Indemnifying Party
has agreed in writing to pay such fees and expenses, (2) the Indemnifying Party shall have failed promptly to assume the defense
of such Proceeding and to employ counsel reasonably satisfactory to such Indemnified Party in any such Proceeding, or (3) the named
parties to any such Proceeding (including any impleaded parties) include both such Indemnified Party and the Indemnifying Party,
and counsel to the Indemnified Party shall reasonably believe that a material conflict of interest is likely to exist if the same
counsel were to represent such Indemnified Party and the Indemnifying Party (in which case, if such Indemnified Party notifies
the Indemnifying Party in writing that it elects to employ separate counsel at the expense of the Indemnifying Party, the Indemnifying
Party shall not have the right to assume the defense thereof and the reasonable fees and expenses of no more than one separate
counsel shall be at the expense of the Indemnifying Party). The Indemnifying Party shall not be liable for any settlement of any
such Proceeding effected without its written consent, which consent shall not be unreasonably withheld or delayed. No Indemnifying
Party shall, without the prior written consent of the Indemnified Party, effect any settlement of any pending Proceeding in respect
of which any Indemnified Party is a party, unless such settlement includes an unconditional release of such Indemnified Party from
all liability on claims that are the subject matter of such Proceeding.

 

Subject
to the terms of this Agreement, all reasonable fees and expenses of the Indemnified Party (including reasonable fees and expenses
to the extent incurred in connection with investigating or preparing to defend such Proceeding in a manner not inconsistent with
this Section) shall be paid to the Indemnified Party, as incurred, within ten Trading Days of written notice thereof to the Indemnifying
Party; provided, that, the Indemnified Party shall promptly reimburse the Indemnifying Party for that portion of such fees and
expenses applicable to such actions for which such Indemnified Party is finally determined by a court of competent jurisdiction
(which determination is not subject to appeal or further review) not to be entitled to indemnification hereunder.

 

(d)              
Contribution. If the indemnification under Section 5(a) or 5(b) is unavailable to an Indemnified Party or insufficient
to hold an Indemnified Party harmless for any Losses, then each Indemnifying Party shall contribute to the amount paid or payable
by such Indemnified Party, in such proportion as is appropriate to reflect the relative fault of the Indemnifying Party and Indemnified
Party in connection with the actions, statements or omissions that resulted in such Losses as well as any other relevant equitable
considerations. The relative fault of such Indemnifying Party and Indemnified Party shall be determined by reference to, among
other things, whether any action in question, including any untrue or alleged untrue statement of a material fact or omission or
alleged omission of a material fact, has been taken or made by, or relates to information supplied by, such Indemnifying Party
or Indemnified Party, and the parties’ relative intent, knowledge, access to information and opportunity to correct or prevent
such action, statement or omission. The amount paid or payable by a party as a result of any Losses shall be deemed to include,
subject to the limitations set forth in this Agreement, any reasonable attorneys’ or other fees or expenses incurred by such
party in connection with any Proceeding to the extent such party would have been indemnified for such fees or expenses if the indemnification
provided for in this Section was available to such party in accordance with its terms.

 

    	 	12	 

     

    

 

The parties
hereto agree that it would not be just and equitable if contribution pursuant to this Section 5(d) were determined by pro rata
allocation or by any other method of allocation that does not take into account the equitable considerations referred to in the
immediately preceding paragraph. In no event shall the contribution obligation of a Holder of Registrable Securities be greater
in amount than the dollar amount of the proceeds (net of all expenses paid by such Holder in connection with any claim relating
to this Section 5 and the amount of any damages such Holder has otherwise been required to pay by reason of such untrue or alleged
untrue statement or omission or alleged omission) received by it upon the sale of the Registrable Securities giving rise to such
contribution obligation.

 

The indemnity
and contribution agreements contained in this Section are in addition to any liability that the Indemnifying Parties may have to
the Indemnified Parties.

 

6.        Miscellaneous.

 

(a)              
Remedies. In the event of a breach by the Company or by a Holder of any of their respective obligations under this
Agreement, each Holder or the Company, as the case may be, in addition to being entitled to exercise all rights granted by law
and under this Agreement, including recovery of damages, shall be entitled to specific performance of its rights under this Agreement.
Each of the Company and each Holder agrees that monetary damages would not provide adequate compensation for any losses incurred
by reason of a breach by it of any of the provisions of this Agreement and hereby further agrees that, in the event of any action
for specific performance in respect of such breach, it shall not assert or shall waive the defense that a remedy at law would be
adequate.

 

(b)              
No Piggyback on Registrations Except as set forth on Schedule 6(b) attached hereto, neither the Company nor
any of its security holders (other than the Holders in such capacity pursuant hereto) may include securities of the Company in
any Registration Statements other than the Registrable Securities.

 

(c)              
[Reserved]

 

(d)              
Discontinued Disposition. By its acquisition of Registrable Securities, each Holder agrees that, upon receipt of
a notice from the Company of the occurrence of any event of the kind described in Section 3(d)(iii) through (vi), such Holder will
forthwith discontinue disposition of such Registrable Securities under a Registration Statement until it is advised in writing
(the “Advice”) by the Company that the use of the applicable Prospectus (as it may have been supplemented or
amended) may be resumed. The Company will use its best efforts to ensure that the use of the Prospectus may be resumed as promptly
as is practicable. The Company agrees and acknowledges that any periods during which the Holder is required to discontinue the
disposition of the Registrable Securities hereunder shall be subject to the provisions of Section 2(d).

 

    	 	13	 

     

    

 

(e)              
Piggy-Back Registrations. If, at any time during the Effectiveness Period, there is not an effective Registration
Statement covering all of the Registrable Securities and the Company shall determine to prepare and file with the Commission a
registration statement relating to an offering for its own account or the account of others under the Securities Act of any of
its equity securities, other than on Form S-4 or Form S-8 (each as promulgated under the Securities Act) or their then equivalents
relating to equity securities to be issued solely in connection with any acquisition of any entity or business or equity securities
issuable in connection with the Company’s stock option or other employee benefit plans, then the Company shall deliver to
each Holder a written notice of such determination and, if within fifteen days after the date of the delivery of such notice, any
such Holder shall so request in writing, the Company shall include in such registration statement all or any part of such Registrable
Securities such Holder requests to be registered; provided, however, that the Company shall not be required to register
any Registrable Securities pursuant to this Section 6(e) that are eligible for resale pursuant to Rule 144 (without volume restrictions
or current public information requirements) promulgated by the Commission pursuant to the Securities Act or that are the subject
of a then effective Registration Statement that is available for resales or other dispositions by such Holder.

 

(f)               
Amendments and Waivers. The provisions of this Agreement, including the provisions of this sentence, may not be amended,
modified or supplemented, and waivers or consents to departures from the provisions hereof may not be given, unless the same shall
be in writing and signed by the Company and the Holders of 51% or more of the then outstanding Registrable Securities (for purposes
of clarification, this includes any Registrable Securities issuable upon exercise or conversion of any Security), provided that,
if any amendment, modification or waiver disproportionately and adversely impacts a Holder (or group of Holders), the consent of
such disproportionately impacted Holder (or group of Holders) shall be required. If a Registration Statement does not register
all of the Registrable Securities pursuant to a waiver or amendment done in compliance with the previous sentence, then the number
of Registrable Securities to be registered for each Holder shall be reduced pro rata among all Holders and each Holder shall have
the right to designate which of its Registrable Securities shall be omitted from such Registration Statement. Notwithstanding the
foregoing, a waiver or consent to depart from the provisions hereof with respect to a matter that relates exclusively to the rights
of a Holder or some Holders and that does not directly or indirectly affect the rights of other Holders may be given only by such
Holder or Holders of all of the Registrable Securities to which such waiver or consent relates; provided, however,
that the provisions of this sentence may not be amended, modified, or supplemented except in accordance with the provisions of
the first sentence of this Section 6(f). No consideration shall be offered or paid to any Person to amend or consent to a waiver
or modification of any provision of this Agreement unless the same consideration also is offered to all of the parties to this
Agreement.

 

    	 	14	 

     

    

 

(g)              
Notices. Any and all notices or other communications or deliveries required or permitted to be provided hereunder
shall be delivered as set forth in the Purchase Agreement.

 

(h)              
Successors and Assigns. This Agreement shall inure to the benefit of and be binding upon the successors and permitted
assigns of each of the parties and shall inure to the benefit of each Holder. The Company may not assign (except by merger) its
rights or obligations hereunder without the prior written consent of all of the Holders of the then outstanding Registrable Securities.
Each Holder may assign their respective rights hereunder in the manner and to the Persons as permitted under Section 5.7 of the
Purchase Agreement.

 

(i)                
No Inconsistent Agreements. Neither the Company nor any of its Subsidiaries has entered, as of the date hereof, nor
shall the Company or any of its Subsidiaries, on or after the date of this Agreement, enter into any agreement with respect to
its securities, that would have the effect of impairing the rights granted to the Holders in this Agreement or otherwise conflicts
with the provisions hereof. Except as set forth on Schedule 6(i), neither the Company nor any of its Subsidiaries has previously
entered into any agreement granting any registration rights with respect to any of its securities to any Person that have not been
satisfied in full.

 

(j)                
Execution and Counterparts. This Agreement may be executed in two or more counterparts, all of which when taken together
shall be considered one and the same agreement and shall become effective when counterparts have been signed by each party and
delivered to the other party, it being understood that both parties need not sign the same counterpart. In the event that any signature
is delivered by facsimile transmission or by e-mail delivery of a “.pdf” format data file, such signature shall create
a valid and binding obligation of the party executing (or on whose behalf such signature is executed) with the same force and effect
as if such facsimile or “.pdf” signature page were an original thereof.

 

(k)              
Governing Law. All questions concerning the construction, validity, enforcement and interpretation of this Agreement
shall be determined in accordance with the provisions of the Purchase Agreement.

 

(l)                
Cumulative Remedies. The remedies provided herein are cumulative and not exclusive of any other remedies provided
by law.

 

(m)            
Severability. If any term, provision, covenant or restriction of this Agreement is held by a court of competent jurisdiction
to be invalid, illegal, void or unenforceable, the remainder of the terms, provisions, covenants and restrictions set forth herein
shall remain in full force and effect and shall in no way be affected, impaired or invalidated, and the parties hereto shall use
their commercially reasonable efforts to find and employ an alternative means to achieve the same or substantially the same result
as that contemplated by such term, provision, covenant or restriction. It is hereby stipulated and declared to be the intention
of the parties that they would have executed the remaining terms, provisions, covenants and restrictions without including any
of such that may be hereafter declared invalid, illegal, void or unenforceable.

 

    	 	15	 

     

    

 

(n)              
Headings. The headings in this Agreement are for convenience only, do not constitute a part of the Agreement and
shall not be deemed to limit or affect any of the provisions hereof.

 

(o)              
Independent Nature of Holders’ Obligations and Rights. The obligations of each Holder hereunder are several
and not joint with the obligations of any other Holder hereunder, and no Holder shall be responsible in any way for the performance
of the obligations of any other Holder hereunder. Nothing contained herein or in any other agreement or document delivered at any
closing, and no action taken by any Holder pursuant hereto or thereto, shall be deemed to constitute the Holders as a partnership,
an association, a joint venture or any other kind of group or entity, or create a presumption that the Holders are in any way acting
in concert or as a group or entity with respect to such obligations or the transactions contemplated by this Agreement or any other
matters, and the Company acknowledges that the Holders are not acting in concert or as a group, and the Company shall not assert
any such claim, with respect to such obligations or transactions. Each Holder shall be entitled to protect and enforce its rights,
including without limitation the rights arising out of this Agreement, and it shall not be necessary for any other Holder to be
joined as an additional party in any proceeding for such purpose. The use of a single agreement with respect to the obligations
of the Company contained was solely in the control of the Company, not the action or decision of any Holder, and was done solely
for the convenience of the Company and not because it was required or requested to do so by any Holder. It is expressly understood
and agreed that each provision contained in this Agreement is between the Company and a Holder, solely, and not between the Company
and the Holders collectively and not between and among Holders.

 

********************

 

 

(Signature
Pages Follow)

 

    	 	16	 

     

    

 

IN WITNESS WHEREOF,
the parties have executed this Registration Rights Agreement as of the date first written above.

 

 

 

	 	SYNAPTOGENIX, INC.
	 	 	 
	 	 	 
	 	By:	 /s/ Robert Weinstein 
	 	Name: Robert Weinstein
	 	Title: Chief Financial Officer

 

 

 

 

 

[SIGNATURE PAGE OF HOLDERS FOLLOWS]

 

     

     

    

 

[SIGNATURE
PAGE OF HOLDERS TO SYNAPTOGENIX RRA]

 

 

Name of Holder: __________________________

 

Signature of Authorized Signatory of Holder: __________________________

 

Name of Authorized Signatory: _________________________

 

Title of Authorized Signatory: __________________________

 

 

 

[SIGNATURE PAGES CONTINUE]

 

     

     

    

Annex A

 

Plan of Distribution

 

Each Selling Stockholder
(the “Selling Stockholders”) of the securities and any of their pledgees, assignees and successors-in-interest
may, from time to time, sell any or all of their securities covered hereby on the principal Trading Market or any other stock exchange,
market or trading facility on which the securities are traded or in private transactions. These sales may be at fixed or negotiated
prices. A Selling Stockholder may use any one or more of the following methods when selling securities:

 

		·	ordinary brokerage transactions and transactions in which the broker-dealer solicits purchasers;

 

		·	block trades in which the broker-dealer will attempt to sell the securities as agent but may position and resell a portion
of the block as principal to facilitate the transaction;

 

		·	purchases by a broker-dealer as principal and resale by the broker-dealer for its account;

 

		·	an exchange distribution in accordance with the rules of the applicable exchange;

 

		·	privately negotiated transactions;

 

		·	settlement of short sales;

 

		·	in transactions through broker-dealers that agree with the Selling Stockholders to sell a specified number of such securities
at a stipulated price per security;

 

		·	through the writing or settlement of options or other hedging transactions, whether through an options exchange or otherwise;

 

		·	a combination of any such methods of sale; or

 

		·	any other method permitted pursuant to applicable law.

 

The Selling Stockholders
may also sell securities under Rule 144 or any other exemption from registration under the Securities Act of 1933, as amended (the
 “Securities Act”), if available, rather than under this prospectus.

 

Broker-dealers engaged
by the Selling Stockholders may arrange for other brokers-dealers to participate in sales. Broker-dealers may receive commissions
or discounts from the Selling Stockholders (or, if any broker-dealer acts as agent for the purchaser of securities, from the purchaser)
in amounts to be negotiated, but, except as set forth in a supplement to this Prospectus, in the case of an agency transaction
not in excess of a customary brokerage commission in compliance with FINRA Rule 2440; and in the case of a principal transaction
a markup or markdown in compliance with FINRA IM-2440.

 

     

     

    

 

In connection with
the sale of the securities or interests therein, the Selling Stockholders may enter into hedging transactions with broker-dealers
or other financial institutions, which may in turn engage in short sales of the securities in the course of hedging the positions
they assume. The Selling Stockholders may also sell securities short and deliver these securities to close out their short positions,
or loan or pledge the securities to broker-dealers that in turn may sell these securities. The Selling Stockholders may also enter
into option or other transactions with broker-dealers or other financial institutions or create one or more derivative securities
which require the delivery to such broker-dealer or other financial institution of securities offered by this prospectus, which
securities such broker-dealer or other financial institution may resell pursuant to this prospectus (as supplemented or amended
to reflect such transaction).

 

The Selling Stockholders
and any broker-dealers or agents that are involved in selling the securities may be deemed to be “underwriters” within
the meaning of the Securities Act in connection with such sales. In such event, any commissions received by such broker-dealers
or agents and any profit on the resale of the securities purchased by them may be deemed to be underwriting commissions or discounts
under the Securities Act. Each Selling Stockholder has informed the Company that it does not have any written or oral agreement
or understanding, directly or indirectly, with any person to distribute the securities.

 

The Company is required
to pay certain fees and expenses incurred by the Company incident to the registration of the securities. The Company has agreed
to indemnify the Selling Stockholders against certain losses, claims, damages and liabilities, including liabilities under the
Securities Act.

 

We agreed to keep this
prospectus effective until the earlier of (i) the date on which the securities may be resold by the Selling Stockholders without
registration and without regard to any volume or manner-of-sale limitations by reason of Rule 144, without the requirement for
the Company to be in compliance with the current public information under Rule 144 under the Securities Act or any other rule of
similar effect or (ii) all of the securities have been sold pursuant to this prospectus or Rule 144 under the Securities Act or
any other rule of similar effect. The resale securities will be sold only through registered or licensed brokers or dealers if
required under applicable state securities laws. In addition, in certain states, the resale securities covered hereby may not be
sold unless they have been registered or qualified for sale in the applicable state or an exemption from the registration or qualification
requirement is available and is complied with.

 

Under applicable rules
and regulations under the Exchange Act, any person engaged in the distribution of the resale securities may not simultaneously
engage in market making activities with respect to the common stock for the applicable restricted period, as defined in Regulation
M, prior to the commencement of the distribution. In addition, the Selling Stockholders will be subject to applicable provisions
of the Exchange Act and the rules and regulations thereunder, including Regulation M, which may limit the timing of purchases and
sales of the common stock by the Selling Stockholders or any other person. We will make copies of this prospectus available to
the Selling Stockholders and have informed them of the need to deliver a copy of this prospectus to each purchaser at or prior
to the time of the sale (including by compliance with Rule 172 under the Securities Act).

 

    	 	2	 

     

    

 

 

SELLING SHAREHOLDERS

 

The common stock being
offered by the selling shareholders are those previously issued to the selling shareholders, and those issuable to the selling
shareholders, upon exercise of the warrants and the pre-funded warrants. For additional information regarding the issuances of
those shares of common stock, warrants and pre-funded warrants, see "Private Placement of Securities" above. We are registering
the shares of common stock in order to permit the selling shareholders to offer the shares for resale from time to time. Except
for the ownership of the shares of common stock, the warrants and the pre-funded warrants, the selling shareholders have not had
any material relationship with us within the past three years.

 

The table below lists
the selling shareholders and other information regarding the beneficial ownership of the shares of common stock by each of the
selling shareholders. The second column lists the number of shares of common stock beneficially owned by each selling shareholder,
based on its ownership of the shares of common stock, warrants and pre-funded warrants, as of ________, 2021, assuming exercise
of the warrants and pre-funded warrants held by the selling shareholders on that date, without regard to any limitations on exercises.

 

The third column lists
the shares of common stock being offered by this prospectus by the selling shareholders.

 

In accordance with
the terms of a registration rights agreement with the selling shareholders, this prospectus generally covers the resale of the
sum of (i) the number of shares of common stock issued to the selling shareholders pursuant to the Purchase Agreement and (ii)
the maximum number of shares of common stock issuable upon exercise of the related warrants and pre-funded warrants, determined
as if the outstanding warrants and pre-funded warrants were exercised in full as of the trading day immediately preceding the date
this registration statement was initially filed with the SEC, each as of the trading day immediately preceding the applicable date
of determination and all subject to adjustment as provided in the registration right agreement, without regard to any limitations
on the exercise of the warrants and the pre-funded warrants. The fourth column assumes the sale of all of the shares offered by
the selling shareholders pursuant to this prospectus.

 

Under the terms of
the warrants and pre-funded warrants, a selling shareholder may not exercise the warrants or pre-funded warrants to the extent
such exercise would cause such selling shareholder, together with its affiliates and attribution parties, to beneficially own a
number of shares of common stock which would exceed [4.99]% of our then outstanding common stock following such exercise, excluding
for purposes of such determination shares of common stock issuable upon exercise of the warrants and pre-funded warrants which
have not been exercised. The number of shares in the second column does not reflect this limitation. The selling shareholders may
sell all, some or none of their shares in this offering. See "Plan of Distribution."

 

    	 	3	 

     

    

 

 

	

Name of Selling Shareholder	Number of shares of 

Common Stock Owned 

Prior to Offering	Maximum Number of 

shares of Common Stock 

to be Sold Pursuant 

to this Prospectus	Number of shares of

 Common Stock Owned 

After Offering

 

 

 

 

    	 	4	 

     

    

 

Annex C

 

Selling Stockholder Notice and Questionnaire

 

The undersigned beneficial
owner of common stock (the “Registrable Securities”) of Synaptogenix, Inc., a Delaware corporation (the “Company”),
understands that the Company has filed or intends to file with the Securities and Exchange Commission (the “Commission”)
a registration statement (the “Registration Statement”) for the registration and resale under Rule 415 of the
Securities Act of 1933, as amended (the “Securities Act”), of the Registrable Securities, in accordance with
the terms of the Registration Rights Agreement (the “Registration Rights Agreement”) to which this document
is annexed. A copy of the Registration Rights Agreement is available from the Company upon request at the address set forth below.
All capitalized terms not otherwise defined herein shall have the meanings ascribed thereto in the Registration Rights Agreement.

 

Certain legal consequences
arise from being named as a selling stockholder in the Registration Statement and the related prospectus. Accordingly, holders
and beneficial owners of Registrable Securities are advised to consult their own securities law counsel regarding the consequences
of being named or not being named as a selling stockholder in the Registration Statement and the related prospectus.

 

NOTICE

 

The undersigned beneficial
owner (the “Selling Stockholder”) of Registrable Securities hereby elects to include the Registrable Securities
owned by it in the Registration Statement.

 

     

     

    

 

The undersigned hereby provides the following
information to the Company and represents and warrants that such information is accurate:

 

QUESTIONNAIRE

 

		1.	Name.

 

		(a)	Full Legal Name of Selling Stockholder

 

	 
	 

 

		(b)	Full Legal Name of Registered Holder (if not the same as (a) above) through which Registrable Securities
are held:

 

	 
	 

 

		(c)	Full Legal Name of Natural Control Person (which means a natural person who directly or indirectly
alone or with others has power to vote or dispose of the securities covered by this Questionnaire):

 

	 
	 

  

2. Address for Notices to Selling
Stockholder:

 

	 
	 
	 
	 
	Telephone:
	 
	Fax:
	 
	Contact Person:
	 

 

3. Broker-Dealer Status:

 

		(a)	Are you a broker-dealer?

 

Yes  ̈    No  ̈

 

		(b)	If “yes” to Section 3(a), did you receive your Registrable Securities as compensation
for investment banking services to the Company?

 

Yes  ̈    No  ̈

 

    	 	2	 

     

    

 

Note:If
 “no” to Section 3(b), the Commission’s staff has indicated that you should be identified as an underwriter in
the Registration Statement.

 

		(c)	Are you an affiliate of a broker-dealer?

 

Yes  ̈    No  ̈

 

		(d)	If you are an affiliate of a broker-dealer, do you certify that you purchased the Registrable Securities
in the ordinary course of business, and at the time of the purchase of the Registrable Securities to be resold, you had no agreements
or understandings, directly or indirectly, with any person to distribute the Registrable Securities?

 

Yes  ̈    No  ̈

 

Note:If
 “no” to Section 3(d), the Commission’s staff has indicated that you should be identified as an underwriter in
the Registration Statement.

 

4. Beneficial Ownership of Securities
of the Company Owned by the Selling Stockholder.

 

Except as set forth below
in this Item 4, the undersigned is not the beneficial or registered owner of any securities of the Company other than the securities
issuable pursuant to the Purchase Agreement.

 

		(a)	Type and Amount of other securities beneficially owned by the Selling Stockholder:

 

	 
	 
	 

 

 

    	 	3	 

     

    

 

5. Relationships with the Company:

 

Except as set forth below,
neither the undersigned nor any of its affiliates, officers, directors or principal equity holders (owners of 5% of more of the
equity securities of the undersigned) has held any position or office or has had any other material relationship with the Company
(or its predecessors or affiliates) during the past three years.

 

State any exceptions here:

 

	 
	 
	 

  

The undersigned agrees
to promptly notify the Company of any material inaccuracies or changes in the information provided herein that may occur subsequent
to the date hereof at any time while the Registration Statement remains effective; provided, that the undersigned shall not be
required to notify the Company of any changes to the number of securities held or owned by the undersigned or its affiliates.

 

By
signing below, the undersigned consents to the disclosure of the information contained herein in its answers to Items 1 through
5 and the inclusion of such information in the Registration Statement and the related prospectus and any amendments or supplements
thereto. The undersigned understands that such information will be relied upon by the Company in
connection with the preparation or amendment of the Registration Statement and the related prospectus and any amendments or supplements
thereto.

 

IN WITNESS WHEREOF
the undersigned, by authority duly given, has caused this Notice and Questionnaire to be executed and delivered either in person
or by its duly authorized agent.

 

	Date: ____________________________	Beneficial Owner: ______________________________________________

 

	 	By:	 
	 	 	Name:
	 	 	Title

  

     

 

PLEASE FAX A COPY (OR EMAIL A .PDF COPY)
OF THE COMPLETED AND EXECUTED NOTICE AND QUESTIONNAIRE TO:

 

 

 

 

    	 	4Exhibit 10.3

 

KATALYST SECURITIES LLC

655 THIRD AVENUE, 18TH FLOOR

NEW YORK, NY 10017

TEL: 212-400-6993 FAX: 212-247-1059

Member: FINRA & SIPC

 

 

January 20, 2021

 

STRICTLY CONFIDENTIAL

 

Mr. Robert Weinstein

CFO

Synaptogenix, Inc.

1185 Avenue of the Americas

3rd Floor

New York, NY 10036

 

Dear Mr. Weinstein:

 

This letter (the “Agreement”)
constitutes our understanding with respect to the engagement of Katalyst Securities LLC (“Katalyst”), registered
broker dealer and member of the Financial Industry Regulatory Authority (“FINRA”) and SIPC, by Synaptogenix,
Inc., a publicly traded corporation duly organized under the laws of the State of Delaware (the “Company”),
to act as a non-exclusive placement agent (the “Placement Agent”) in connection with the private placement of
securities of the Company (the “Securities”) (the “Offering”). The Offering will raise
up to a total of $14,000,000 (the “Offering Amount”) from the sale of (i) an aggregate of 9,335,533 shares of
the Company’s common stock (the “Common Stock”), par value $0.0001 per share (each a “Share”),
(ii) Series E warrants to purchase up to an aggregate of 9,335,533 shares of Common Stock, with a term of one (1) year from the
effectiveness of the registration statement and an exercise price equal to $2.1275, and (iii) Series F warrants to purchase up
to an aggregate of 9,335,533 shares of Common Stock, with a term of five (5) years from the date of issuance and an exercise price
of $1.725. Each Share, Series E Warrant and Series F Warrant will be sold together for an aggregate purchase price of $1.50. Nothing
herein implies that the Placement Agent would have the power or authority to bind the Company or an obligation of the Company to
issue any Securities or proceed with any proposed transaction. The Offering will be made pursuant to the exemptions afforded by
Section 4(a)(2) of the Securities Act of 1933, as amended (the “Act”), and Regulation D promulgated thereunder
and applicable state securities laws. The closing of the Offering Amount is anticipated on or about January 25, 2021, or at such
time and place as mutually agreed to by the Company and the Placement Agent at the Closing as defined below (the “Offering
Period”).

 

A.       Appointment
of Katalyst.

 

During the Term (as
defined below), the Company hereby engages the Placement Agent to serve as a non-exclusive placement agent in connection with the
Offering and the Placement Agent hereby accepts such engagement on a “reasonable best efforts” basis upon the terms
and conditions set forth herein. Katalyst may offer the Securities through other broker-dealers who are FINRA members (collectively,
the “Sub Agents”) and may reallow all or a portion of Katalyst’s Broker Fees (as defined in Section B(a)
and B(b) below) it receives to such other Sub Agents or pay a finders or consultant fee as allowed by applicable law.

 

    	 	1	 

     

    

 

The Company acknowledges
and agrees that Katalyst’s engagement hereunder is not an agreement or commitment, express or implied, by Katalyst or any
of its affiliates to underwrite or purchase any securities or otherwise provide financing. The proposed private placement is to
be made directly by the Company to the investors pursuant to agreements entered between the investors and the Company. Purchases
of Securities may be made by the Placement Agent and their respective officers, directors, employees and affiliates and by the
officers, directors, employees and affiliates of the Company (collectively, the “Affiliates”) for the Offering
and such purchases will be made by the Affiliates based solely upon the same information that is provided to the investors in the
Offering.

 

B.       Fees
 & Expenses.

 

(a)       Cash
Portion. The Company hereby agrees to pay the Placement Agent (or the designees authorized by such Placement
Agent), as a condition to the Closing of the Offering, as compensation for their services hereunder, a cash fee equal to Ten Percent
(10%) of the gross proceeds from any sale of Securities in the Offering sold to Investors introduced by the Placement Agent participating
in the Closing (the “Placement Agent Cash Fee”). The Placement Agent Cash Fee will be paid by the Company in
the name provided to the Company by the Placement Agent at the time of the closing.

 

(b)       Warrant
Portion. At the final Closing of the Offering, the Company will issue to the Placement Agent (or the designees authorized
by such Placement Agent), as compensation for its services hereunder, warrants to purchase a number of shares of Common Stock equal
to Ten Percent (10%) of the number of shares of Common Stock sold to Investors introduced by the Placement Agent participating
in the Offering (the “Placement Agent Warrants”). The Placement Agent Warrants will have with a term of five
(5) years from the final Closing of the Offering, an exercise price equal to $1.725 per share, shall be immediately exercisable,
include cashless exercise provisions if there is no effective registration statement covering the Placement Agent Warrants and
piggyback registration rights, a net exercise provision (including contemporaneously with a future sale of the Company) and include
customary anti-dilution provisions covering stock splits, dividends, mergers and similar transactions. The Placement Agent Cash
Fee and the Placement Agent Warrants are sometimes referred to collectively as the “Placement Agent Fees”).
The Placement Agent Warrants may be issued directly to the Placement Agent’s employees and affiliates at the Placement Agent’s
written request and will be issued within the (10) calendar days from the final Close (as defined below).

 

(c)       Expenses.
In addition to the Broker Fee payable pursuant to Sections B(a) and (b), the Company hereby agrees to pay Katalyst’s legal
and compliance fees with the engagement hereunder in the amount of Ten Thousand Dollars ($10,000) (the “KLCF”)
paid directly by the Company at the time of the Closing from the gross proceeds. Regardless whether the Offering is consummated
and if there is no Closing, the KLCF will be due and payable within five (5) days of written request to the Company by wire transfer.
The KLCF is separate and apart from the Placement Agent Cash Fee and is in addition to the reimbursement of fees and expenses set
forth in Appendix I relating to indemnification and contribution. For avoidance of doubt, the KLCF Fee does not include (i) any
legal fees for counsels retained to file federal, state or regulatory filings as required to be filed by the Company, (ii) other
Placement Agent’s counsel fees, if any, (iii) Company’s counsel fees.

 

    	 	2	 

     

    

 

C.       Term
and Termination of Engagement.

 

Except as set forth
below, the term of this Agreement begins on the date of this Agreement and shall end automatically upon the earlier to occur of
(i) after final Closing of the Offering or (ii) the date of termination of the Offering (the “Term”). Notwithstanding
the Term of this Agreement, this Agreement may be earlier terminated immediately by the Company or the Placement Agent in the event
of either the Company’s or the Placement Agent’s failure to perform any of its material obligations hereunder or fraud,
illegal or willful misconduct or gross negligence (the “Termination Date”). Notwithstanding any such expiration
or termination, the terms of this Agreement other than Paragraphs A, D, and E shall all remain in full force and effect and be
binding on the parties hereto, including the exculpation, indemnification and contribution obligations of the Company, the confidentiality
obligations, and the right of the Placement Agent to receive any earned but unpaid Placement Agent Fees hereunder and the right
of the Placement Agent to receive reimbursement for the Katalyst Legal Fee in accordance with paragraph B(c) above.

 

D.Subscription
and Closing Procedures. 

 

(a)       The
Company shall cause to be delivered to the Placement Agent copies of any offering documents (the “Offering Documents”)
related to the Offering and hereby consents to the use of such copies for the purposes permitted by the Act and applicable securities
laws and in accordance with the terms and conditions of this Agreement, and hereby authorizes the Placement Agent and its agents
and employees to use the Offering Documents in connection with the sale of the Securities until the earlier of (i) the Termination
Date or (ii) the Final Closing, and no person or entity is or will be authorized to give any information or make any representations
other than those contained in the Offering Documents or to use any offering materials other than the Offering Documents in connection
with the sale of the Securities, unless the Company first provides the Placement Agent with notification of such information, representations
or offering materials.

 

(b)       The
Company shall make available to the Placement Agent and its representatives such information, including, but not limited to, financial
information, and other information regarding the Company (the “Information”), as may be reasonably requested
in making a reasonable investigation of the Company and its affairs. The Company shall provide access to the officers, directors,
employees, independent accountants, legal counsel and other advisors and consultants of the Company as shall be reasonably requested
by the Placement Agent. The Company recognizes and agrees that the Placement Agent (i) will use and rely primarily on the Information
and generally available information from recognized public sources in performing the services contemplated by this Agreement without
independently verifying the Information or such other information, (ii) does not assume responsibility for the accuracy of the
Information or such other information, and (iii) will not make an appraisal of any assets or liabilities owned or controlled by
the Company or its market competitors.

 

(c)       Each
prospective investor will be required to complete and execute the Offering Documents, which may include, but not be limited to,
Securities or Stock Purchase Agreement, Registration Rights Agreement, Anti-Money Laundering Form, Accredited Investor Certification,
and other documents which will be forwarded or delivered to the address identified in the Offering Documents.

 

(d)       Simultaneously
with the delivery to the Placement Agent of the Offering Documents, the investor’s check or other good funds will be forwarded
directly by the investor to the Company. Subject to the receipt of subscriptions for the amount for Closing, the Company will either
accept or reject, for any or no reason, the Offering Documents in a timely fashion and at the Closing, if applicable. will countersign
the Offering Documents and provide duplicate copies of such documents to the Placement Agent. The Company will forward directly
to the investors the documents countersigned by the Company. The Company will give notice to the Placement Agent of its acceptance
of each subscription. The Company, or the Placement Agent on the Company’s behalf, will promptly return to investors incomplete,
improperly completed, improperly executed and rejected subscriptions and give written notice thereof to the Placement Agent upon
such return.

 

    	 	3	 

     

    

 

(e)       If
subscriptions for the Offering Amount for the closing have been accepted prior to the Termination Date, the funds therefor have
been collected by the Company and all of the conditions set forth elsewhere in this Agreement are fulfilled, a closing shall be
held promptly with respect to the Securities sold (the “Closing”). Prior to the occurrence of a Closing, the
Company shall not be permitted to utilize any funds received by any investors. Delivery of payment for the accepted subscriptions
for the Securities will be made at the time of the Closing at the Placement Agent’s office against delivery of the Securities
by the Company at the address set forth in Section 12 hereof (or at such other place as may be mutually agreed upon between the
Company and the Placement Agent), net of amounts agreed upon by the parties herein, including, the Blue Sky counsel as of such
Closing. Executed certificates for the Securities will be in such authorized denominations and registered in such names as the
Placement Agent may request on or before the date of the Closing (“Closing Date”). The certificates will be
forwarded to the subscriber directly by the stock transfer agent within ten (10) business days following the Closing. At the Closing,
the Company will deliver irrevocable issuance instruction to its stock transfer agent for the issuance of certificates representing
the Securities being sold.

 

(f)       If
Offering Documents for the amount for the Offering Amount has not been received and accepted by the Company on or before the Termination
Date for any reason, the Offering will be terminated, no Securities will be sold, and the Company will, at the request of the Placement
Agent, cause all monies received from investors for the Securities to be promptly returned to such investors without interest,
penalty, expense or deduction.

 

E.       Representations,
Warranties and Covenants. The Company represents and warrants to, and agrees with, the Placement Agent that:

 

(a)       The
Company represents and warrants that it has all requisite power and authority to enter and carry out the terms and provisions of
this Agreement. The execution, delivery and performance of this Agreement and the Offering of Securities will not violate or conflict
with any provision of the charter or bylaws of the Company or, except as would not have a material adverse effect, any agreement
or other instrument to which the Company is a party or by which it or any of its properties is bound. Any necessary approvals,
governmental and private, will be obtained by the Company prior to the Closing, except as may be waived or obtained or filed following
the Closing and except where the failure to obtain any such approval would not have a material adverse effect.

 

    	 	4	 

     

    

 

(b)       The
Securities will be offered and sold by the Company in compliance with the requirements for the exemption from registration pursuant
to Section 5 of the Securities Act of 1933, as amended (including any applicable exemption therefrom), and with all other securities
laws and regulations. The Company will file appropriate notices with the Securities and Exchange Commission and with other applicable
securities authorities.

 

(c)       The
information in any investor presentation materials, memorandum or other offering documents furnished to investors in the Offering
by the Company is true and correct in all material respects and does not contain any untrue statement of a material fact or omit
to state a material fact required to be stated or necessary to make the statements therein not misleading.

 

(d)       The
Company hereby permits the Placement Agent to rely on the representations and warranties made or given by the Company to any acquirer
of Securities in any agreement, certificate or otherwise in connection with the Offering.

 

F.       Indemnification
and Contribution. The Company agrees to indemnify Katalyst and its controlling persons, representatives and agents in
accordance with the indemnification provisions set forth in Appendix I. These provisions will apply regardless of whether
any Offering is consummated.

 

G.       Limitation
of Engagement to the Company. The Company acknowledges that Katalyst has been retained only by the Company, that Katalyst
is providing services hereunder as an independent contractor (and not in any fiduciary or agency capacity) and that the Company’s
engagement of Katalyst is not deemed to be on behalf of, and is not intended to confer rights upon, any shareholder, owner or partner
of the Company or any other person not a party hereto as against Katalyst or any of its respective affiliates, or any of their
respective officers, directors, controlling persons (within the meaning of Section 15 of the Securities Act or Section 20 of the
Securities Exchange Act of 1934, as amended (the “Exchange Act”), employees or agents. Unless otherwise expressly
agreed in writing by Katalyst, no one other than the Company is authorized to rely upon this Agreement or any other statements
or conduct of Katalyst, and no one other than the Company is intended to be a beneficiary of this Agreement. The Company acknowledges
that any recommendation or advice, written or oral, given by Katalyst to the Company in connection with Katalyst’s engagement
is intended solely for the benefit and use of the Company’s management and directors in considering a possible Offering,
and any such recommendation or advice is not on behalf of, and shall not confer any rights or remedies upon, any other person or
be used or relied upon for any other purpose. Katalyst shall not have the authority to make any commitment binding on the Company.
The Company, in its sole discretion, shall have the right to reject any investor introduced to it by Katalyst, or its respective
designees or affiliates.

 

H.       Limitation
of Placement Agent’s Liability to the Company. Katalyst shall not have any liability to the Company for any Losses
attributable to the gross negligence, intentional misrepresentation or willful misconduct of another Placement Agent.

 

I.       Governing
Law. This Agreement shall be deemed to have been made and delivered in New York City and shall be governed as to validity,
interpretation, construction, effect and in all other respects by the internal laws of the State of New York applicable to contracts
to be wholly performed in said state.

 

J.       Information;
Reliance. The Company shall furnish, or cause to be furnished, to the Placement Agent all information reasonably requested
by the Placement Agent for the purpose of rendering services hereunder and shall further make available to the Placement Agent
all such information to the same extent and on the same terms as such information is available to the Company and potential lenders
and investors (all such information being the “Information”). The Company shall notify the Placement Agent if
it becomes aware of any material adverse change, or development that may lead to a material adverse change, in the business, properties,
operations or financial condition or prospects of the Company or any other material Information to the extent needed to allow the
Company and the Placement agent to assess whether any disclosure to investors, a delay of the date of the Closing, or other any
other appropriate step is required. In addition, the Company agrees to make available to the Placement Agent upon request from
time to time the officers, directors, accountants, counsel and other advisors of the Company. The Company recognizes and confirms
that the Placement Agent (a) will use and rely on the Information and Offering Documents, including private placement memorandum,
and on information available from generally recognized public sources in performing the services contemplated by this Agreement
without having independently verified the same; (b) will not assume responsibility for the accuracy or completeness of the Offering
Documents or the Information and such other information, except for any written information furnished to the Company by the Placement
Agent specifically for inclusion in the Offering Documents; and (c) will not make an appraisal of any of the assets or liabilities
of the Company. Upon reasonable request, the Company will meet with the Placement Agent or its representatives to discuss all information
relevant for disclosure in the Offering Documents and will cooperate in any investigation undertaken by the Placement Agent thereof,
including any document included therein. At the Closing, at the request of the Placement Agent, the Company shall deliver copies
of such officer’s certificates, in form and substance reasonably satisfactory to the Placement Agent and its counsel as is
customary for such Offering.

 

    	 	5	 

     

    

 

K.       Use
of Information. The Company authorizes the Placement Agent to transmit to the prospective investors of Securities the
Company’s power point presentation prepared by the Company and/or private placement memorandum (if any, and if prepared by
the Company) (the “Presentation Materials”). The Company represents and warrants that the Presentation Materials
(i) will be prepared by the management of the Company; and (ii) will not contain any untrue statement of a material fact or omit
to state a material fact required to be stated therein or necessary to make the statements therein not misleading. The Company
will advise the Placement Agent promptly if it becomes aware of the occurrence of any event or any other change known to the Company
which results in the Presentation Materials containing an untrue statement of a material fact or omitting to state a material fact
required to be stated therein or necessary to make the statements therein or previously made, in light of the circumstances under
which they were made, not misleading. Notwithstanding the foregoing, if any Placement Agent elects to not transmit Presentation
Materials to prospective investors, such Placement Agent shall direct qualified prospective investors to an electronic data room
in which the Company makes available the Presentation Materials for review by qualified prospective investors.

 

L.       Announcement
of Transaction. The Company and the Placement Agent acknowledge and agree that Katalyst may, subsequent to the Closing
of the Offering and to the extent Katalyst receives a Placement Agent Fee for Securities sold in the Offering, make public its
involvement with the Company provided that any such public announcement or other public disclosure (other than customary tombstone
presentations or other investment banking presentation materials containing only publicly available information) shall be approved
by the Company, which approval shall not be unreasonably withheld.

 

M.       Advice
to the Board. The Company acknowledges that any advice given by the Placement Agent to the Company is solely for the
benefit and use of the Company’s board of directors and officers, who will make all decisions regarding whether and how to
pursue any opportunity or transaction. The Company’s board of directors and senior management may consider the Placement
Agent’s advice but will base their decisions on the advice of legal, tax and other business advisors and other factors which
they consider appropriate. Accordingly, as an independent contractor, Katalyst will not assume the responsibilities of a fiduciary
to the Company or its stockholders in connection with the performance of its services. Any advice provided may not be used, reproduced,
disseminated, quoted or referred to without the Placement Agent’s prior written consent. Katalyst does not provide accounting,
tax, or legal advice. Katalyst is not responsible for the success of any Offering. The Company is a sophisticated business enterprise
that has retained the Placement Agent for the limited purposes set forth in this Agreement. The parties acknowledge and agree that
their respective rights and obligations are contractual in nature. Each party disclaims an intention to impose fiduciary obligations
on the other by virtue of the engagement contemplated by this Agreement.

 

    	 	6	 

     

    

 

N.       Entire
Agreement. This Agreement was drafted by the Company and the Placement Agent’s respective counsels and constitutes
the entire Agreement between the parties and supersedes and cancels any and all prior or contemporaneous arrangements, understandings
and agreements, written or oral, between them relating to the subject matter hereof.

 

O.       Amendment.
This Agreement may not be modified except in writing signed by each of the parties hereto.

 

P.       No
Partnership. The Company is a sophisticated business enterprise that has retained the Placement Agent for the limited
purposes set forth in this Agreement. The parties acknowledge and agree that their respective rights and obligations are contractual
in nature. Each party disclaims an intention to impose fiduciary obligations on the other by virtue of the engagement contemplated
by this Agreement.

 

Q.       Notice.
All notices and other communications required hereunder shall be in writing and shall be deemed effectively given to a party by
(a) personal delivery; (b) upon deposit with the United States Post Office, by certified mail, return receipt requested, first-class
mail, postage prepaid; (c) delivered by hand or by messenger or overnight courier, addressee signature required, to the addresses
below or at such other address and/or to such other persons as shall have been furnished by the parties;

 

 

	If to the Company:	Synaptogenix, Inc.
	 	1185 Avenue of the Americas
	 	3rd Floor
	 	New York, NY 10036
	 	Attention:  Robert Weinstein, CFO
	 	Email: rweinstein@synaptogen.com
	 	 
	With a copy to:	Mintz, Levin, Cohn, Ferris Glovsky & Popeo, PC
	(which shall not	666 Third Avenue
	     constitute notice)	New York, NY 10017
	 	Attention: Daniel Bagliebter, Esq.
	 	Email: dabagliebeter@mintz.com

 

    	 	7	 

     

    

 

	If to Katalyst Securities LLC.	Katalyst Securities, LLC
	 	655 Third Avenue, 18th Floor
	 	New York, NY 10017
	 	Attention: Michael Silverman
	 	Managing Director
	 	 
	With a copy to:	Barbara J. Glenns, Esq.
	(which shall not constitute notice)	Law Office of Barbara J. Glenns, Esq.
	 	30 Waterside Plaza, Suite 7
	 	New York, NY 10010

  

R.       Severability.
If any term, provision, covenant or restriction herein is held by a court of competent jurisdiction to be invalid, void or unenforceable
or against public policy, the remainder of the terms, provisions and restrictions contained herein will remain in full force and
effect and will in no way be affected, impaired or invalidated.

 

S.        Governing
Law and Jurisdiction. This Agreement shall be deemed to have been made and delivered in New York City and shall be governed
as to validity, interpretation, construction, effect and in all other respects by the internal laws of the State of New York without
regard to principles of conflicts of law thereof.

 

THE
PARTIES HERETO AGREE TO SUBMIT ALL CONTROVERSIES TO THE EXCLUSIVE JURISDICTION OF FINRA ARBITRATION IN ACCORDANCE WITH THE PROVISIONS
SET FORTH BELOW AND UNDERSTAND THAT (A) ARBITRATION IS FINAL AND BINDING ON THE PARTIES, (B) THE PARTIES ARE WAIVING THEIR RIGHTS
TO SEEK REMEDIES IN COURT, INCLUDING THE RIGHT TO A JURY TRIAL, (C) PRE-ARBITRATION DISCOVERY IS GENERALLY MORE LIMITED AND DIFFERENT
FROM COURT PROCEEDINGS, (D) THE ARBITRATOR’S AWARD IS NOT REQUIRED TO INCLUDE FACTUAL FINDINGS OR LEGAL REASONING AND ANY
PARTY’S RIGHT TO APPEAL OR TO SEEK MODIFICATION OF RULES BY ARBITRATORS IS STRICTLY LIMITED, (E) THE PANEL OF FINRA ARBITRATORS
WILL TYPICALLY INCLUDE A MINORITY OF ARBITRATORS WHO WERE OR ARE AFFILIATED WITH THE SECURITIES INDUSTRY, AND (F) ALL CONTROVERSIES
WHICH MAY ARISE BETWEEN THE PARTIES CONCERNING THIS AGREEMENT SHALL BE DETERMINED BY ARBITRATION PURSUANT TO THE RULES THEN PERTAINING
TO FINRA. ALL QUESTIONS CONCERNING THE CONSTRUCTION, VALIDITY, ENFORCEMENT AND INTERPRETATION OF THIS AGREEMENT SHALL BE GOVERNED
BY AND CONSTRUED AND ENFORCED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK. JUDGMENT ON ANY AWARD OF ANY SUCH ARBITRATION
MAY BE ENTERED IN THE SUPREME COURT OF THE STATE OF NEW YORK OR IN ANY OTHER COURT HAVING JURISDICTION OVER THE PERSON OR PERSONS
AGAINST WHOM SUCH AWARD IS RENDERED. THE PARTIES AGREE THAT THE DETERMINATION OF THE ARBITRATORS SHALL BE BINDING AND CONCLUSIVE
UPON THEM. THE PREVAILING PARTY, AS DETERMINED BY SUCH ARBITRATORS, IN A LEGAL PROCEEDING SHALL BE ENTITLED TO COLLECT ANY COSTS,
DISBURSEMENTS AND REASONABLE ATTORNEY’S FEES FROM THE OTHER PARTY.  PRIOR TO FILING AN ARBITRATION, THE PARTIES
HEREBY AGREE THAT THEY WILL ATTEMPT TO RESOLVE THEIR DIFFERENCES FIRST BY SUBMITTING THE MATTER FOR RESOLUTION TO A MEDIATOR, ACCEPTABLE
TO ALL PARTIES, AND WHOSE EXPENSES WILL BE BORNE EQUALLY BY ALL PARTIES. THE MEDIATION WILL BE HELD IN THE COUNTY OF NEW YORK,
STATE OF NEW YORK, ON AN EXPEDITED BASIS. IF THE PARTIES CANNOT SUCCESSFULLY RESOLVE THEIR DIFFERENCES THROUGH MEDIATION, THE MATTER
WILL BE RESOLVED BY ARBITRATION. THE ARBITRATION SHALL TAKE PLACE IN THE COUNTY OF NEW YORK, THE STATE OF NEW YORK, ON AN EXPEDITED
BASIS. 

 

    	 	8	 

     

    

 

T.       Other
Investment Banking Services. The Company acknowledges that Katalyst and its affiliates are securities firms engaged
in securities trading and brokerage activities and providing investment banking and financial advisory services. In the ordinary
course of business, the Placement Agent and its affiliates, registered representatives and employees may at any time hold long
or short positions, and may trade or otherwise effect transactions, for their own account or the accounts of customers, in the
Company’s debt or equity securities, the Company’s affiliates or other entities that may be involved in the transactions
contemplated by this Agreement. In addition, the Placement Agent and its affiliates may from time to time perform various investment
banking and financial advisory services for other clients and customers who may have conflicting interests with respect to the
Company or an Offering. The Company also acknowledges that the Placement Agent and its affiliates have no obligation to use in
connection with this engagement or to furnish to the Company, confidential information obtained from other companies. Furthermore,
the Company acknowledges the Placement Agent may have fiduciary or other relationships whereby the Placement Agent or its affiliates
may exercise voting power over securities of various persons, which securities may from time to time include securities of the
Company or others with interests in respect of any Offering. The Company acknowledges that the Placement Agent or such affiliates
may exercise such powers and otherwise perform their functions in connection with such fiduciary or other relationships without
regard to the defined relationship to the Company hereunder.

 

U.       Miscellaneous.

 

(a)              
This Agreement shall be binding upon and inure to the benefit of the Placement Agent and the Company and their respective assigns,
successors, and legal representatives.

  

(b)              
This Agreement may be executed in counterparts (including facsimile or in pdf format counterparts), each of which shall be deemed
an original but all of which together shall constitute one and the same instrument.

 

(c)              
Notwithstanding anything herein to the contrary, in the event that the Placement Agent determines that any of the terms provided
for hereunder shall not comply with a FINRA rule, including but not limited to FINRA Rule 5110, then the Company shall agree to
amend this Agreement in writing upon the request of the Placement Agent to comply with any such rules; provided that any such amendments
shall not provide for terms that are less favorable to the Company.

 

    	 	9	 

     

    

 

V.       Confidentiality.

 

(a)        The
Placement Agent will maintain the confidentiality of the Information and, unless and until such Information shall have been made
publicly available by the Company or by others without breach of a confidentiality agreement, shall disclose the Information only
as provided for herein, authorized by the Company or as required by law or by request of a governmental authority, FINRA or court
of competent jurisdiction. In the event the Placement Agent is legally required to make disclosure of any of the Information,
the Placement Agent will give prompt notice to the Company prior to such disclosure, to the extent the Placement Agent can practically
do so. 

 

(b)       The
foregoing paragraph shall not apply to information that:

 

(i) at the
time of disclosure by the Company, is or thereafter becomes, generally available to the public or within the industries in which
the Company conducts business, other than as a result of a breach by the Placement Agent of its obligations under this Agreement;
or

 

(ii) prior
to or at the time of disclosure by the Company, was already in the possession of, the Placement Agent or any of its affiliates,
or could have been developed by them from information then lawfully in their possession, by the application of other information
or techniques in their possession, generally available to the public; at the time of disclosure by the Company thereafter, is obtained
by the Placement Agent or any of its affiliates from a third party who the Placement Agent reasonably believes to be in possession
of the information not in violation of any contractual, legal or fiduciary obligation to the Company with respect to that information;
or is independently developed by the Placement Agent or its affiliates.

 

The exclusions
set forth in sub-section (b) above shall not apply to pro forma financial information of the Company, which pro forma Information
shall in all events be subject to sub- section (a) above.

 

(c) Nothing in this
Agreement shall be construed to limit the ability of the Placement Agent or its affiliates to pursue, investigate, analyze, invest
in, or engage in investment banking, financial advisory or any other business relationship with entities other than the Company,
notwithstanding that such entities may be engaged in a business which is similar to or competitive with the business of the Company,
and notwithstanding that such entities may have actual or potential operations, products, services, plans, ideas, customers or
supplies similar or identical to the Company’s, or may have been identified by the Company as potential merger or acquisition
targets or potential candidates for some other business combination, cooperation or relationship. The Company expressly acknowledges
and agrees that it does not claim any proprietary interest in the identity of any other entity in its industry or otherwise, and
that the identity of any such entity is not confidential information.

 

    	 	10	 

     

    

 

W.       No
Disqualification Events.

 

		(a)	The Company represents and warrants the following:

 

(i)
None of Company, any director, executive officer, other officer of the Company participating in the Offering, any beneficial owner
of 20% or more of the Company’s outstanding voting equity securities, calculated on the basis of voting power, nor any promoter
(as that term is defined in Rule 405 under the Securities Act) connected with the Company in any capacity at the time of sale (each,
an “Issuer Covered Person” and, together, “Issuer Covered Persons”) is subject to any Disqualification
Event (as defined below), except for a Disqualification Event covered by Rule 506(d)(2) or (d)(3) or has been involved in any matter
which would be a Disqualification Event except for the fact that it occurred before September 23, 2013. The Company has exercised
reasonable care to determine whether any Covered Person is subject to a Disqualification Event. The Company has complied, to the
extent applicable, with its disclosure obligations under Rule 506(e), and has furnished to the Placement Agent a copy of any disclosures
provided thereunder. 

  

(ii) The Company will
promptly notify Katalyst in writing if the Company becomes aware of (A) any Disqualification Event relating to any Issuer Covered
Person and (B) any event that would, with the passage of time, become a Disqualification Event relating to any Issuer Covered Person.

 

(iii) The Company is
aware that other persons (other that any Issuer Covered Persons and the Placement Agent Covered Person (as defined below) will
be paid (directly or indirectly) remuneration for solicitation of investors in connection with the sale of any Securities.

 

(b) The Placement Agent
represents and warrants the following:

 

(i)
No Disqualification Events. Neither it, nor to its knowledge any of its directors, executive officers, general partners, managing
members or other officers participating in the Offering (each, a “Placement Agent Covered Person” and, together,
 “Placement Agent Covered Persons”), is subject to any of the “Bad Actor” disqualifications currently
described in Rule 506(d)(1)(i) to (viii) under the Securities Act (a “Disqualification Event”) or has been involved
in any matter which would be a Disqualification Event except for the fact that it occurred before September 23, 2013.

  

(ii) Other Covered
Persons. The Placement Agent is aware that other persons (other than any Issuer Covered Person or Placement Agent Covered Person)
will be paid (directly or indirectly) remuneration for solicitation of investors in connection with the sale of any Securities.

 

(iii) Notice of Disqualification
Events.  The Placement Agent will notify the Company promptly in writing upon the Placement Agent learning of (A) any Disqualification
Event relating to any Placement Agent Covered Person not previously disclosed to the Company in accordance with the provisions
of this Section and (B) any event that would, with the passage of time, become a Disqualification Event relating to any Placement
Agent Covered Person.

 

[Signature Page Follows]

 

    	 	11	 

     

    

 

 

In acknowledgment that
the foregoing correctly sets forth the understanding reached by the Placement Agent and the Company, please sign in the space provided
below, whereupon this letter shall constitute a binding Agreement as of the date first indicated above.

 

 

This
Agreement contains a pre-dispute arbitration provision in Paragraph S.

 

	 	SYNAPTOGENIX, INC.
	 	 	 
	 	 	 
	 	By:	/s/ Robert Weinstein
	 	 	Robert Weinstein
	 	 	Chief Financial Officer

	 	 	 
	 	 	 
	 	KATALYST SECURITIES LLC
	 	 	 
	 	 	 
	 	By:	/s/ Michael A. Silverman
	 	 	Michael A. Silverman
	 	 	Managing Director

 

 

    	 	12	 

     

    

 

AppendiX
I

 

INDEMNIFICATION AND CONTRIBUTION

 

The Company agrees
to indemnify and hold harmless the Placement Agent, its affiliates, officers, directors, employees, agents and controlling persons
(each an “Indemnified Person”) from and against any and all losses, claims, damages, liabilities and expenses,
to which any such Indemnified Person may become subject arising out of or in connection with the transactions contemplated in the
Agreement to which this Appendix I is attached (the “Agreement”), insofar as such loss, claim, damage,
liability or expense arises out of or is based upon any untrue statement of a material fact or omission to state a material fact
in Offering Documents required to be stated therein or necessary to make the statements therein not misleading in any litigation,
investigation or proceeding (collectively, the “Proceedings”), regardless of whether any of such Indemnified
Person is a party to the Agreement, and to reimburse such Indemnified Persons for any reasonable and documented legal or other
expenses as they are incurred in connection with investigating, responding to or defending against in any Proceeding, provided
that the foregoing indemnification will not, as to any Indemnified Person, apply to losses, claims, damages, liabilities or expenses
to the extent that they are finally judicially determined to have resulted primarily and directly from the fraud, gross negligence
or willful misconduct of an Indemnified Person; and provided, further, that the foregoing indemnification will not apply to any
loss, claim, damage, liability or expense arising out of or based upon any written information furnished to the Company by the
Placement Agent specifically for inclusion in the Offering Documents; provided further that the Company shall only have the obligation
to reimburse an Indemnified Person if such Indemnified Person provides to the Company a written undertaking of such Indemnified
Person to repay to the Company the amount so advanced to the extent that any such reimbursement is so held to have been improper
in a final judgment by a court of competent jurisdiction, and if the court of competent jurisdiction holds that such reimbursement
was improper, such Indemnified Person shall promptly return any amount advanced to it by the Company. The Company also agrees that
no Indemnified Person shall have any liability (whether direct or indirect, in contract, tort or otherwise) to the Company its
affiliates, officers, directors employees, agents, creditors or stockholders, directly or indirectly, for or in connection with
the Agreement, any transactions contemplated in the Agreement, or the Placement Agent’s role or services in connection with
the Agreement, except to the extent that any liability for losses, claims, demands, damages, liabilities or expenses incurred by
the Company are finally judicially determined to have resulted primarily from the fraud, gross negligence or willful misconduct
of such Indemnified Person or have resulted from any written information furnished to the Company by the Placements Agent specifically
for inclusion in the Offering Documents. The Company will be liable to pay the legal fees, expenses and costs incurred by Katalyst’s
legal team related to any lawsuit but will not be obligated to pay the legal fees of a sub dealer brought in by Katalyst if named
in the lawsuit, unless agree to by the Company. If the Company engages additional Placement Agents in addition to Katalyst, then
the Company will be liable for those Placement Agents’ legal fees, expenses and costs separate and apart to the legal fees,
expenses and costs incurred by and due Katalyst’s legal team.

 

If for any reason the
foregoing indemnification is unavailable to any Indemnified Person or insufficient to hold it harmless, then the Company and the
Placement Agent in accordance with the contributions provisions herein, shall contribute to the amount paid or payable by such
Indemnified Person as a result of such loss, claim, damage, liability or expense in such proportion as is appropriate to reflect
not only the relative benefits received by the Company on the one hand and Katalyst on the other hand, but also the relative fault
of the Company and Katalyst, as well as any relevant equitable considerations; provided that, in no event, will the aggregate contribution
of Katalyst hereunder exceed the amount of fees actually received by Katalyst pursuant to this Agreement and in no event will the
aggregate contribution of the Company hereunder exceed the amount of proceeds received by the Company through the sale of Securities
in the Offering to investors first contacted by Katalyst. The indemnity, reimbursement and contribution obligations of the Company
under this Agreement will bind and inure to the benefit of any successors, assigns, heirs and personal representatives of the Company
and any Indemnified Person.

 

    	 	13	 

     

    

 

Promptly after receipt
by an Indemnified Person of notice of the commencement of any Proceedings, that Indemnified Person will, if a claim is to be made
under this indemnity agreement against the Company in respect of the Proceedings, notify the Company in writing of the commencement
of the Proceedings; provided that (i) the omission so to notify the Company will not relieve the Company from any liability that
the Company may have under this indemnity agreement except to the extent the Company has been materially prejudiced by such omission,
and (ii) the omission to so notify the Company will not relieve the Company from any liability that the Company may have to an
Indemnified Person otherwise than on account of this indemnity agreement. In case any Proceedings are brought against any Indemnified
Person and it notifies the Company of the commencement of the Proceedings, the Company will be entitled to participate in the Proceedings
and, to the extent that it may elect by written notice delivered to the Indemnified Person, to assume the defense of the Proceedings
with counsel reasonably satisfactory to the Indemnified Person; provided that, if the defendants in any Proceedings include both
the Indemnified Person and the Company and the Indemnified Person concludes that there may be legal defenses available to the Indemnified
Person that are different from or in addition to those available to the Company, the Indemnified Person has the right to select
separate counsel to assert those legal defenses and to otherwise participate in the defense of the Proceedings on its behalf at
its sole expense. Upon receipt of notice from the Company to the Indemnified Person of its election to assume the defense of the
Proceedings, the Company will not be liable to the Indemnified Person for expenses incurred by the Indemnified Person in connection
with the defense of the Proceedings (other than reasonable costs of investigation) unless the Company authorizes, in writing, the
employment of counsel for the Indemnified Person and expressly agrees in writing to be liable for the reasonable expenses of such
legal counsel.

 

The Company will not
be liable for any settlement of any Proceedings effected without its written consent (which consent must not be unreasonably withheld),
but if settled with the Company’s written consent or if a final judgment for the plaintiff in any such Proceedings is delivered,
the Company agrees to indemnify and hold harmless each Indemnified Person from and against any and all losses, claims, damages,
liabilities and expenses by reason of such settlement or judgment. The Company may not, without the prior written consent of an
Indemnified Person (which consent shall not be unreasonably withheld), effect any settlement of any pending or threatened Proceedings
in respect of which indemnity could have been sought under this indemnity agreement by such Indemnified Person unless the settlement
includes an unconditional release of the Indemnified Person, in form and substance reasonably satisfactory to the Indemnified Person,
from all liability on claims that are the subject matter of such Proceedings.

 

The Company’s
reimbursement, indemnity and contribution obligations hereunder will be in addition to any liability that it may otherwise have.

 

Capitalized terms used
but not defined in this Appendix I have the meanings assigned to such terms in the Agreement.

 

    	 	14

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