Document:

REGISTRATION RIGHTS AGREEMENT DATED MAY 10, 2004

 Exhibit 4.3 
  

OSCIENT PHARMACEUTICALS CORPORATION 
 31⁄2% Senior Convertible Notes due 2011 
 REGISTRATION RIGHTS AGREEMENT 
 May 10, 2004 
  
 J.P. Morgan Securities Inc. 
 Merrill Lynch, Pierce, Fenner & Smith
Incorporated 
 c/o J.P. Morgan Securities Inc. 
 277 Park Avenue

 New York, New York 10172 
  
 Ladies and Gentlemen: 
  
 Oscient Pharmaceuticals Corporation, a Massachusetts corporation (the “Company”), proposes to issue and sell (such issuance and sale, the
“Initial Placement”) to the Initial Purchasers (as defined below), upon the terms set forth in a purchase agreement, dated May 4, 2004 (the “Purchase Agreement”), $125,000,000 aggregate principal amount, plus an
option (the “Option”) to purchase up to an additional $18,750,000 aggregate principal amount, of its 31⁄2% Senior Convertible Notes due 2011 (the “Securities”). The Securities will be convertible into shares of
Common Stock (as defined herein), at the conversion price set forth in the Offering Memorandum (as defined herein), as the same may be adjusted from time to time pursuant to the Indenture (as defined herein). As an inducement to you to enter into
the Purchase Agreement and in satisfaction of a condition to your obligations thereunder, the Company agrees with you, (i) for your benefit and (ii) for the benefit of the Holders (as defined herein) from time to time of the Securities and the
shares of Common Stock issuable upon conversion of the Securities, as follows: 
  
 1. Definitions. Capitalized terms used herein without definition shall have the respective meanings set forth in the Purchase Agreement. As used in this Agreement, the following capitalized terms shall have the following meanings:

  
 “Affiliate” of any specified person means any
other person directly or indirectly controlling or controlled by or under direct or indirect common control with such specified person. For the purposes of this definition, “control” (including, with correlative meanings, the terms
“controlling,” “controlled by” and “under common control with”), as used with respect to any person, shall mean the possession, directly or indirectly, of the power to direct or cause the direction of the management or
policies of such person whether through the ownership of voting securities or by agreement or otherwise. 
  
 “Business Day” has the meaning set forth in the Indenture. 
  
 “Closing Date” means the date of the closing of the sale of the Firm Securities as contemplated by the
Purchase Agreement. 
  
 “Common Stock” means the
common stock, par value $0.10 per share, of the Company, as it exists on the date of this Agreement and any other shares of capital stock or other securities of the Company into which such Common Stock may be reclassified or changed, together with

  

 
any and all other securities which may from time to time be issuable upon conversion of Securities. 
  
 “Company” has the meaning set forth in the preamble hereto.

  
 “Exchange Act” means the Securities Exchange
Act of 1934, as amended, and the rules and regulations of the SEC promulgated thereunder. 
  
 “Holder” means a person who is a holder or beneficial owner of any Securities or shares of Common Stock issuable upon conversion of Securities; provided that, unless otherwise expressly stated
herein, only registered holders of Securities or Common Stock issued on conversion thereof shall be counted for purposes of calculating any proportion of holders entitled to take any action or give notice pursuant to this Agreement. 
  
 “Holder Information” with respect to any Holder means
information with respect to such Holder required to be included in any Shelf Registration Statement or the related Prospectus pursuant to the Securities Act and which information is included therein in reliance upon and in conformity with
information furnished to the Company in writing by such Holder for inclusion therein. 
  
 “Indenture” means the Indenture relating to the Securities, to be dated on or about May 10, 2004, and to be entered into between the Company and U.S. Bank National Association, as Trustee, as the same
may be amended from time to time in accordance with the terms thereof. 
  
 “Initial Placement” has the meaning set forth in the preamble hereto. 
  
 “Initial Purchasers” means J.P. Morgan Securities Inc. and Merrill Lynch, Pierce, Fenner & Smith Incorporated. 
  
 “Liquidated Damages” has the meaning set forth in Section
2(e) hereof. 
  
 “Liquidated Damages Payment
Date” means each April 15 and October 15. 
  
 “Losses” has the meaning set forth in Section 5(d) hereof. 
  
 “Majority Holders” means the Holders of a majority of the then outstanding aggregate principal amount of Securities being registered under a Shelf Registration Statement; provided that Holders
of the shares of Common Stock issued upon conversion of Securities shall be deemed to be Holders of the aggregate principal amount of Securities from which such Common Stock was converted; and provided further, that Securities or
shares of Common Stock which have been sold or otherwise transferred pursuant to the Shelf Registration Statement shall not be included in the calculation of Majority Holders. 
  
 “NASD” means the National Association of Securities Dealers, Inc. 
  
 “Notice and Questionnaire” means a Selling Securityholder
Notice and Questionnaire substantially in the form of Annex A to the Offering Memorandum. 
  

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 “Notice Holder” means any Holder of Transfer Restricted Securities that has delivered a
properly completed and signed Notice and Questionnaire to the Company in accordance with Section 2(b) hereof. 
  
 “Offering Memorandum” means the Final Memorandum as defined in the Purchase Agreement. 
  
 “Option” has the meaning set forth in the preamble hereto.

  
 “Person” has the meaning set forth in the
Indenture. 
  
 “Prospectus” means the prospectus
included in any Shelf Registration Statement (including, without limitation, a prospectus that discloses information previously omitted from a prospectus filed as part of an effective registration statement in reliance upon Rule 430A under the
Securities Act), as amended or supplemented by any prospectus supplement, with respect to the terms of the offering of any portion of the Securities or shares of Common Stock issuable upon conversion thereof covered by such Shelf Registration
Statement, and all amendments and supplements to such prospectus, including all documents incorporated or deemed to be incorporated by reference in such prospectus. 
  
 “Purchase Agreement” has the meaning set forth in the preamble hereto. 
  
 “Questionnaire Deadline” has the meaning set forth in
Section 2(b) hereof. 
  
 “Record Holder” means
each person who is registered on the books of the registrar as the holder of Securities at the close of business on April 1 and October 1 immediately preceding such Liquidated Damages Payment Date. 
  
 “Registration Default” has the meaning set forth in Section
2(e) hereof. 
  
 “Rule 144” means Rule 144 under
the Securities Act (or any similar provision then in force). 
  
 “Rule 144A” means Rule 144A under the Securities Act (or any successor provision promulgated by the SEC). 
  
 “Rule 144(k)” means Rule 144(k) under the Securities Act (or any successor provision promulgated by the SEC). 
  
 “Rule 415” means Rule 415 under the Securities Act (or any
successor provision promulgated by the SEC). 
  
 “SEC” means the Securities and Exchange Commission. 
  
 “Securities” has the meaning set forth in the preamble hereto. 
  
 “Securities Act” means the Securities Act of 1933, as amended, and the rules and regulations of the SEC promulgated thereunder.

  

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 “Shelf Registration” means a registration effected pursuant to Section 2 hereof.

  
 “Shelf Registration Period” has the meaning
set forth in Section 2(c) hereof. 
  
 “Shelf Registration
Statement” means any “shelf” registration statement of the Company filed pursuant to the provisions of Section 2 hereof which covers the Transfer Restricted Securities on Form S-3 or on another appropriate form (as determined by
the Company) for an offering to be made on a delayed or continuous basis pursuant to Rule 415 and all amendments and supplements to such registration statement, including post-effective amendments, in each case including the Prospectus contained
therein, all exhibits thereto and all documents incorporated or deemed to be incorporated by reference therein. 
  
 “Suspension Period” has the meaning set forth in Section 2(d) hereof. 
  
 “Transfer Restricted Securities” means each Security and each share of Common Stock issuable upon
conversion thereof (and any security issued with respect thereto upon any stock dividend, split or similar event) until the earliest of the date on which such Security or share of Common Stock, or any security issued with respect thereto upon any
stock dividend, split or similar event, as the case may be: (i) has been transferred pursuant to a Shelf Registration Statement or another registration statement covering such Security or share of Common Stock which has been filed with the SEC
pursuant to the Securities Act, in either case after such registration statement has become effective and while such registration statement is effective under the Securities Act; (ii) has been transferred pursuant to Rule 144 (or any similar
provision then in force); (iii) may be sold or transferred pursuant to Rule 144(k) (or any successor provision promulgated by the SEC); or (iv) ceases to be outstanding. Notwithstanding the foregoing, each Security and each share of Common Stock
issuable upon conversion thereof (and any security issued with respect thereto upon any stock dividend, split or similar event) that has not previously ceased to be a Transfer Restricted Security pursuant to the previous sentence shall cease to be a
Transfer Restricted Security on the date that is two (2) years after the later of the Closing Date or the latest Option Closing Date (as defined in the Purchase Agreement). 
  
 “Trustee” means the trustee with respect to the Securities under the Indenture. 
  
 All references in this Agreement to financial statements and schedules and
other information which is “contained,” “included,” or “stated” in the Shelf Registration Statement, any preliminary Prospectus or Prospectus (and all other references of like import) shall be
deemed to mean and include all such financial statements and schedules and other information incorporated or deemed to be incorporated by reference in such Shelf Registration Statement, preliminary Prospectus or Prospectus, as the case may be; and
all references in this Agreement to amendments or supplements to the Shelf Registration Statement, any preliminary Prospectus or Prospectus shall be deemed to mean and include any document filed with the SEC under the Exchange Act, after the date of
such Shelf Registration Statement, preliminary Prospectus or Prospectus, as the case may be, which is incorporated or deemed to be incorporated by reference therein. 
  

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 2. Shelf Registration Statement. 
  
 (a) The Company shall, at its expense, prepare and file with the SEC within 90 days following the Closing Date a Shelf
Registration Statement with respect to resales of the Transfer Restricted Securities by the Holders from time to time on a delayed or continuous basis pursuant to Rule 415 and in accordance with the methods of distribution set forth in such Shelf
Registration Statement and thereafter shall use its reasonable best efforts to cause such Shelf Registration Statement to be declared effective under the Securities Act within 210 days after the Closing Date; provided that if any Securities
are issued upon exercise of the Option granted to the Initial Purchasers in the Purchase Agreement and the date on which such Securities are issued occurs after the Closing Date, the Company will take such steps, prior to the effective date of the
Shelf Registration Statement, to ensure that such Securities issued upon an exercise of the Option and the shares of Common Stock issuable upon conversion thereof are included in the Shelf Registration Statement on the same terms as the Securities
issued on the Closing Date. The Company shall supplement or amend the Shelf Registration Statement if required by the rules, regulations or instructions applicable to the registration form used by the Company for the Shelf Registration Statement, or
by the Securities Act, the Exchange Act or the SEC. 
  
 (b) (i)
The Company shall name each Holder that delivers a properly completed and signed Notice and Questionnaire to the Company as a selling security holder in the Shelf Registration Statement. A Holder of Transfer Restricted Securities may include such
securities in the Shelf Registration Statement only if the Holder sends by first-class registered mail or by courier with delivery confirmation, a properly completed Notice and Questionnaire to the Company. In order to be included in the Shelf
Registration Statement at the time of its effectiveness, the Notice and Questionnaire must be sent on or prior to the 20th Business Day after the date the Notice and Questionnaire is deemed to have been given in accordance with Section 7(c) hereof (or, in the case of a Holder that is a transferee of Transfer Restricted Securities, on or prior to the
earlier of (x) the 20th Business Day after the completion of the transfer of Transfer Restricted Securities to the
transferee and (y) 9:00 a.m., New York time, on the fifth Business Day prior to initial effectiveness of the Shelf Registration Statement) (in any case, the “Questionnaire Deadline”). The Company agrees and undertakes that it shall
distribute a Notice and Questionnaire (A) no later than 30 Business Days prior to the expected effectiveness of the Shelf Registration Statement to each Holder in accordance with Section 7(c) hereof, and (B) in the case of a Holder that is a
transferee of Transfer Restricted Securities, upon the request of such transferee Holder given in accordance with Section 7(c) hereof, to such Holder at the address set forth in such request. 
  
 (ii) Following the effectiveness of the Shelf Registration
Statement, upon receipt of a completed Notice and Questionnaire from a Holder, the Company will, as promptly as practicable, but in any event within 10 Business Days after its receipt thereof, file any amendments to the Shelf Registration Statement
or supplements to the related Prospectus as are necessary to permit the Holder to deliver the Prospectus to purchasers of Transfer Restricted Securities (subject to the right of the Company to suspend the use of the Prospectus as described in
Section 2(d) hereof), provided, however, that (i) if a supplement to the related Prospectus is required to permit the Holder (or other Holders not included in the Shelf Registration Statement 

  

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upon effectiveness) to deliver the Prospectus to purchasers of Transfer Restricted Securities, the Company shall not be required to file more than one (1)
such supplement during any twenty (20) day period and (ii) if a post effective amendment to the Shelf Registration Statement is required to permit the Holder (or other Holders not included in the Shelf Registration Statement upon effectiveness) to
deliver the Prospectus to purchasers of Transfer Restricted Securities, the Company shall not be required to file more than one (1) post-effective amendment to the Shelf Registration Statement in any sixty (60) day period. The Company shall use its
reasonable best efforts to cause any such post-effective amendment to become effective under the Securities Act as promptly as is practicable; provided, that if a Notice and Questionnaire is delivered to the Company during a Suspension
Period, the Company shall not be obligated to amend the Shelf Registration Statement or supplement the Prospectus until the termination of such Suspension Period. 
  
 (iii) Each Holder as to which the Shelf Registration Statement is being effected agrees to furnish promptly
to the Company (x) such other information as the Company may reasonably request for use in connection with the Shelf Registration Statement or Prospectus or in any application to be filed with or under state securities laws and (y) all information
required to be disclosed in order to make the information previously furnished to the Company by such Holder not misleading. 
  
 (c) The Company shall use its reasonable best efforts to keep the Shelf Registration Statement continuously effective, supplemented and amended under the
Securities Act in order to permit the Prospectus forming a part thereof to be usable, subject to Section 2(d) hereof, by all Notice Holders until the earliest to occur of: (i) the last date on which in the opinion of counsel to the Company the
holding period applicable to sales of all Transfer Restricted Securities under Rule 144(k) has expired; (ii) the date as of which all Transfer Restricted Securities have been transferred under Rule 144; (iii) such date as of which all Transfer
Restricted Securities have been sold pursuant to the Shelf Registration Statement; and (iv) the date that is two (2) years after the later of the Closing Date or the latest Option Closing Date (as defined in the Purchase Agreement) (in any such
case, such period being called the “Shelf Registration Period”). The Company will, in order to fulfill its obligations and this Section 2(c): (x) subject to Section 2(d), prepare and file with the SEC such amendments and
post-effective amendments to the Shelf Registration Statement as may be necessary to keep the Shelf Registration Statement continuously effective for the Shelf Registration Period; (y) subject to Section 2(d), cause the related Prospectus to be
supplemented by any required supplement, and as so supplemented to be filed pursuant to Rule 424 (or any similar provisions then in force) under the Securities Act; and (z) comply in all material respects with the provisions of the Securities Act
with respect to the disposition of all Transfer Restricted Securities covered by the Shelf Registration Statement during the Shelf Registration Period. 
  
 (d) The Company may suspend the availability of any Shelf Registration Statement and the use of any Prospectus (the period during which the availability
of any Shelf Registration Statement and any Prospectus may be suspended herein referred to as the “Suspension Period”), without incurring any obligation to pay Liquidated Damages pursuant to Section 2(e), for a period not to exceed:
(i) 45 consecutive days at any one time; (ii) 45 days in the aggregate in any three-month period; or (iii) 120 days in the aggregate during any 12-month period, in each case only for valid business reasons, to be determined in good faith by the
Company in its sole 

  

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judgment (which shall not include the avoidance of the Company’s obligations hereunder), including, without limitation, the acquisition or divestiture
of assets, pending corporate developments, public filings with the SEC and similar events; provided that if the suspension of the Shelf Registration Statement relates to a previously undisclosed proposed or pending material business
transaction, the disclosure of which, in the sole judgment of the Company, would impede the Company’s ability to consummate such transaction, the Company may extend the Suspension Period set forth in (i) and (ii) above to 75 days;
provided further, that the Company promptly thereafter complies with the requirements of Section 3(j) hereof, if applicable. 
  
 (e) The Company and the Initial Purchasers agree that the Holders of Transfer Restricted Securities will suffer damages, and it would not be feasible to
ascertain the extent of such damages with precision, if the Company fails to fulfill its obligations under Section 2 hereof. Accordingly, if: (i) the Shelf Registration Statement is not filed with the SEC on or within 90 days after the Closing Date;
(ii) the Shelf Registration Statement has not been declared effective by the SEC within 210 days after the Closing Date; or (iii) the Shelf Registration Statement is filed and declared effective but shall thereafter cease to be effective (without
being succeeded immediately by a replacement Shelf Registration Statement filed and declared effective) or usable (including as a result of a Suspension Period) for the offer and sale of Transfer Restricted Securities for a period of time (including
any Suspension Period) which exceeds: (x) 45 consecutive days at any time; (y) 45 days in the aggregate in any three-month period; or (z) 120 days in the aggregate in any 12-month period (each such event referred to in clauses (i) through (iii), a
“Registration Default”), provided that any suspension of the Shelf Registration Statement as a result of the time required by the SEC to declare effective a post-effective amendment to the Shelf Registration Statement in
connection with the Company’s obligation to file such an amendment pursuant to Section 2(d)(ii) hereof shall not be included in the calculation of a Registration Default; the Company shall pay to each Notice Holder (who is also a Record Holder)
during any period in which a Registration Default has occurred or is continuing in an amount (the “Liquidated Damages”) equal to: (i) one-quarter of one percent (25 basis points) per annum per $1,000 principal amount of Securities
constituting Transfer Restricted Securities for the period up to and including the 90th day during which such Registration Default has occurred and is continuing; and (ii) one-half of one percent (50 basis points) per annum per $1,000 principal
amount of Securities constituting Transfer Restricted Securities for the period including and subsequent to the 91st day during which such Registration Default has occurred and is continuing, it being understood that all calculations pursuant to
this and the preceding sentence shall be carried out to five decimal places. Following the cure of all Registration Defaults, Liquidated Damages will cease to accrue with respect to such Registration Defaults. All accrued Liquidated Damages shall be
paid by the Company on each Liquidated Damages Payment Date in cash to the date of such cure and Liquidated Damages will be calculated on the basis of a 360-day year consisting of twelve 30-day months. The parties hereto agree that the Liquidated
Damages provided for in this Section 2(e) constitute a reasonable estimate of the damages that may be incurred by Holders by reason of a Registration Default and that such Liquidated Damages are the only monetary damages available to Holders in the
event of a Registration Default. Notwithstanding anything in the Agreement to the contrary, Liquidated Damages shall only be payable to Notice Holders. 
  
 (f) All of the Company’s obligations (including, without limitation, the obligation to pay Liquidated Damages) set forth in the preceding paragraph
which are outstanding or exist 

  

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with respect to any Transfer Restricted Security at the time such security ceases to be a Transfer Restricted Security shall survive until such time as all
such obligations with respect to such security shall have been satisfied in full. Notwithstanding the foregoing, no Liquidated Damages shall accrue as to any Transfer Restricted Security from and after the earlier of: (i) the date such security is
no longer a Transfer Restricted Security; and (ii) the expiration of the Shelf Registration Period. 
  
 (g) Immediately upon the occurrence or the termination of a Registration Default, the Company shall give the Trustee, so long as the Securities remain
outstanding, notice of such commencement or termination of the obligation to pay Liquidated Damages with regard to the Securities, and the amount thereof and of the nature of the default giving rise to such commencement or the event giving rise to
such termination, as the case may be (such notice to be contained in an Officer’s Certificate (as such term is defined in the Indenture)), and prior to receipt of such Officer’s Certificate the Trustee and the transfer and paying agent
shall be entitled to assume that no such commencement or termination has occurred, as the case may be. 
  
 3. Registration Procedures. In connection with any Shelf Registration Statement, the following provisions shall apply: 
  
 (a) The Company shall: (i) furnish to the Initial Purchasers, within a reasonable period of time, but in any event within three Business Days, prior to
the filing thereof with the SEC to afford the Initial Purchasers and their counsel a reasonable opportunity for review, a copy of each Shelf Registration Statement, and each amendment thereof, and a copy of each Prospectus, and each amendment or
supplement thereto (excluding amendments caused by the filing of a report under the Exchange Act), and shall reflect in each such document, when so filed with the SEC, such comments as the Initial Purchasers may reasonably propose, except to the
extent the Company reasonably determines it to be inadvisable or inappropriate to reflect such comments therein; and (ii) include information regarding the Notice Holders and the methods of distribution they have elected for their Transfer
Restricted Securities provided to the Company in Notice and Questionnaires as necessary to permit such distribution by the methods specified therein. 
  
 (b) Subject to Section 2(d), the Company shall ensure that: (i) any Shelf Registration Statement and any amendment thereto and any Prospectus forming a
part thereof and any amendment or supplement thereto comply in all material respects with the Securities Act and the rules and regulations thereunder; (ii) any Shelf Registration Statement and any amendment thereto does not, when it becomes
effective, contain an untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein not misleading; and (iii) any Prospectus forming a part of any Shelf Registration
Statement, and any amendment or supplement to such Prospectus, does not include an untrue statement of a material fact or omit to state a material fact necessary in order to make the statements therein, in light of the circumstances under which they
were made, not misleading; provided that the Company makes no representation with respect to any Holder Information. 
  

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 (c) The Company, as promptly as reasonably practicable (but in any event within two Business Days), shall
notify the Initial Purchasers and each Notice Holder: 
  
 (i) when any Prospectus or any supplement thereto has been filed with the SEC and when the Shelf Registration Statement or any post-effective amendment thereto has become effective; 
  
 (ii) of the issuance by the SEC or any other federal or
state governmental authority of any stop order suspending the effectiveness of the Shelf Registration Statement or of any order preventing or suspending the use of any Prospectus or the initiation or threat of any proceedings for that purpose;

  
 (iii) of the receipt by the Company of any
notification with respect to the suspension of the qualification or exemption from qualification of the Transfer Restricted Securities included in any Shelf Registration Statement for sale in any jurisdiction or the initiation or threat of any
proceeding for that purpose; 
  
 (iv) of the
occurrence of, but not the nature of or details concerning, any event or the existence of any condition that requires the making of any changes in the Shelf Registration Statement or the Prospectus or any document incorporated by reference therein
so that, as of such date, the statements therein are not misleading and the Shelf Registration Statement or the Prospectus or any document incorporated by reference therein, as the case may be, does not include an untrue statement of a material fact
or omit to state a material fact required to be stated therein or necessary to make the statements therein (in the case of the Prospectus, in light of the circumstances under which they were made) not misleading; 
  
 (v) of the Company’s determination that a
post-effective amendment to the Shelf Registration Statement is necessary (other than a post-effective amendment pursuant to Section 2(b)(ii)); and 
  
 (vi) of the commencement (including as a result of any of the events or circumstances described in paragraph (ii) above) and termination
of any Suspension Period. 
  
 (d) The Company shall use its
reasonable best efforts to obtain: (i) the withdrawal of any order suspending the effectiveness of any Shelf Registration Statement and the use of any related Prospectus; and (ii) the lifting of any suspension of the qualification (or exemption from
qualification) of any of the Transfer Restricted Securities for offer or sale in any jurisdiction in which they have been qualified for sale, in each case at the earliest possible time, and shall provide notice to each Notice Holder and the Initial
Purchasers of the withdrawal of any such orders or suspensions. 
  
 (e) The Company shall promptly furnish to the Initial Purchasers (and, upon written request from any Notice Holder to such Notice Holder), without charge, at least one copy of any Shelf Registration Statement and any post-effective
amendment thereto, excluding all documents incorporated or deemed to be incorporated therein by reference and all exhibits thereto. 
  
 (f) The Company shall, during the Shelf Registration Period, promptly deliver to the Initial Purchasers and each Notice Holder, without charge, as many
copies of the Prospectus (including each preliminary Prospectus) included in any Shelf Registration Statement, and any amendment or supplement thereto, as such person may reasonably request and except as provided in Sections 2(d) and 3(p) hereof;
and the Company hereby consents to the use of the 

  

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Prospectus and any amendment or supplement thereto by each of the selling Holders in connection with the offering and sale of the Transfer Restricted
Securities covered by the Prospectus or any amendment or supplement thereto. 
  
 (g) Prior to any offering of Transfer Restricted Securities pursuant to any Shelf Registration Statement, the Company shall register or qualify or cooperate with the Notice Holders and their respective counsel in
connection with the registration or qualification (or exemption from such registration or qualification) of such Transfer Restricted Securities for offer and sale, under the securities or blue sky laws of such jurisdictions within the United States
as any such Notice Holders reasonably request and shall maintain such qualification in effect so long as required and do any and all other acts or things necessary or advisable to enable the offer and sale in such jurisdictions of the Transfer
Restricted Securities covered by such Shelf Registration Statement; provided, however, that the Company will not be required to: (i) qualify generally to do business as a foreign corporation or as a dealer in securities in any
jurisdiction where it is not then so qualified or; (ii) take any action which would subject it to service of process or taxation in excess of a nominal dollar amount in any such jurisdiction where it is not then so subject. 
  
 (h) If the Transfer Restricted Securities are in certificated form, the
Company shall cooperate with the Holders to facilitate the timely preparation and delivery of certificates representing Transfer Restricted Securities sold pursuant to any Shelf Registration Statement free of any restrictive legends and, with
respect of any Securities, in such denominations permitted by the Indenture and registered in such names as Holders may request at least two Business Days prior to settlement of sales of Transfer Restricted Securities pursuant to such Shelf
Registration Statement. 
  
 (i) Subject to the exceptions
contained in (i) and (ii) of Section 3(g) above, the Company shall use its reasonable best efforts to cause the Transfer Restricted Securities covered by the applicable Shelf Registration Statement to be registered with or approved by such other
federal, state and local governmental agencies or authorities, and self-regulatory organizations in the United States as may be necessary to enable the Holders to consummate the disposition of such Transfer Restricted Securities as contemplated by
the Shelf Registration Statement; without limitation to the foregoing, the Company shall provide all such information as may be required by the NASD in connection with the offering under the Shelf Registration Statement of the Transfer Restricted
Securities (including, without limitation, such as may be required by NASD Rule 2710 or 2720), and shall cooperate with each Holder in connection with any filings required to be made with the NASD by such Holder in that regard. 
  
 (j) Upon the occurrence of any event described in Section 3(c)(iv) or 3(c)(v)
hereof, the Company shall promptly prepare and file with the SEC a post-effective amendment to any Shelf Registration Statement, or an amendment or supplement to the related Prospectus, or any document incorporated therein by reference, or file a
document which is incorporated or deemed to be incorporated by reference in such Shelf Registration Statement or Prospectus, as the case may be, so that, as thereafter delivered to purchasers of the Transfer Restricted Securities included therein,
the Shelf Registration Statement and the Prospectus, in each case as then amended or supplemented, will not include an untrue statement of a material fact or omit to state any material fact required to be stated therein or necessary in order to make
the statements 

  

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therein (in the case of the Prospectus, in light of the circumstances under which they were made) not misleading and, in the case of a post-effective
amendment, use its reasonable best efforts to cause it to become effective as promptly as practicable; provided that the Company’s obligations under this paragraph (j) shall be suspended if the Company has suspended the use of the
Prospectus in accordance with Section 2(d) hereof and given notice of such suspension to Notice Holders, it being understood that the Company’s obligations under this Section 3(j) shall be automatically reinstated at the end of such Suspension
Period. 
  
 (k) The Company shall provide, prior to the effective
date of any Shelf Registration Statement hereunder a CUSIP number for the Transfer Restricted Securities registered under such Shelf Registration Statement. 
  
 (l) The Company shall use its reasonable best efforts to comply with all applicable rules and regulations of the SEC and shall make generally available to
its security holders an earnings statement satisfying the provisions of Section 11(a) of the Securities Act and Rule 158 promulgated by the SEC thereunder (or any similar rule promulgated under the Securities Act) for a 12-month period commencing on
the first day of the first fiscal quarter of the Company commencing after the effective date of any Shelf Registration Statement or each post-effective amendment to any Shelf Registration Statement, which such statements shall be made available no
later than 45 days after the end of the 12-month period or 90 days after the end of the 12-month period, if the 12-month period coincides with the fiscal year of the Company. 
  
 (m) The Company shall use its reasonable best efforts to cause the Indenture to be qualified under the TIA (as defined in
the Indenture) not later than the effective date of the first Shelf Registration Statement. 
  
 (n) The Company shall cause all shares of Common Stock issuable upon conversion of the Securities to be reserved for listing on each securities exchange or quotation system on which the Common Stock is then listed no
later than the date the applicable Shelf Registration Statement is declared effective and, shall cause all Common Stock to be so listed when issued, and, in connection therewith, to make such filings as may be required under the Exchange Act and to
have such filings declared effective as and when required thereunder. 
  
 (o) If reasonably requested in writing in connection with any disposition of Transfer Restricted Securities pursuant to a Shelf Registration Statement, make reasonably available for inspection during normal business hours by a
representative for the Notice Holders of such Transfer Restricted Securities and any broker-dealers, attorneys and accountants retained by such Notice Holders, all relevant financial and other records, pertinent corporate documents and properties of
the Company and its subsidiaries, and cause the appropriate executive officers, directors and designated employees of the Company and its subsidiaries to make reasonably available for inspection during normal business hours all relevant information
reasonably requested by such representative for the Notice Holders or any such broker-dealers, attorneys or accountants in connection with such disposition, in each case as is customary for similar “due diligence” examinations;
provided, however, that any information that is designated by the Company, in good faith, as confidential at the time of delivery of such information shall be kept confidential by such persons, unless disclosure thereof is made in
connection with a court, administrative or regulatory proceeding or required by law, or such information has become 

  

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available to the public generally through the Company or through a third party without an accompanying obligation of confidentiality. 
  
 (p) Each Notice Holder agrees that, upon receipt of notice of the happening
of an event described in Sections 3(c)(ii) through and including 3(c)(vi), it shall forthwith discontinue (and shall cause its agents and representatives to discontinue) disposition of Transfer Restricted Securities and will not resume disposition
of Transfer Restricted Securities until such Holder has received copies of an amended or supplemented Prospectus contemplated by Section 3(j) hereof, or until such Notice Holder is advised in writing by the Company that the use of the Prospectus may
be resumed or that the relevant Suspension Period has been terminated, as the case may be, provided that the foregoing shall not prevent the sale, transfer or other disposition of Transfer Restricted Securities by a Holder in a transaction
which is exempt from, or not subject to, the registration requirements of the Securities Act, so long as such Holder does not and is not required to deliver the applicable Prospectus or Shelf Registration Statement in connection with such sale,
transfer or other disposition, as the case may be; and provided, further, that the provisions of this Section 3(p) shall not prevent the occurrence of a Registration Default or otherwise limit the obligation of the Company to pay
Liquidated Damages. 
  
 (q) The Company shall use its reasonable
best efforts to take all other steps necessary to effect the registration of the Securities covered by the Shelf Registration Statement contemplated hereby. 
  
 4. Registration Expenses. The Company shall bear all fees and expenses incurred in connection with the performance of its obligations under Sections 2 and 3 hereof
and shall reimburse the Holders for the reasonable fees and disbursements of one firm or counsel designated by the Company (and reasonably acceptable to the Initial Purchasers acting on behalf of the Holders) to act as counsel for the Holders in
connection therewith. Such fees and expenses shall include, without limitation: (i) all registration and filing fees and expenses (including filings made with the NASD); (ii) all fees and expenses of compliance with federal securities and state Blue
Sky or securities laws; (iii) all expenses of printing (including printing of Prospectuses and certificates for the Common Stock to be issued upon conversion of the Securities) and the Company’s expenses for messenger and delivery services and
telephone; (iv) all fees and disbursements of counsel to the Company; (v) all application and filing fees in connection with listing (or authorizing for quotation) the Common Stock on a national securities exchange or automated quotation system
pursuant to the requirements hereof; and (vi) all fees and disbursements of independent certified public accountants of the Company. The Company shall bear its internal expenses (including, without limitation, all salaries and expenses of their
officers and employees performing legal, accounting or other duties), the expenses of any annual audit and the fees and expenses of any Person, including special experts, retained by the Company. Notwithstanding the provisions of this Section 4,
each Holder shall bear the expense of any broker’s commission, agency fee and underwriter’s discount or commission (including, without limitation, the expenses related to the engagement of a “qualified independent underwriter”),
if any, relating to the sale or disposition of such Holder’s Transfer Restricted Securities pursuant to a Shelf Registration Statement. 
  

 - 12 - 

 5. Indemnification and Contribution. 
  
 (a) The Company agrees to indemnify and hold harmless each Holder of Transfer Restricted Securities covered by any Shelf
Registration Statement (including, without limitation, each Initial Purchaser), its directors, officers, and employees and each person, if any, who controls any such Holder within the meaning of either the Securities Act or the Exchange Act
(collectively referred to for purposes of this Section 5 as a “Holder”) against any losses, claims, damages or liabilities, joint or several, or actions in respect thereof, to which any of them may become subject, under the
Securities Act or otherwise, insofar as such losses, claims, damages, liabilities or actions arise out of or are based upon an untrue statement or alleged untrue statement of a material fact contained in the Shelf Registration Statement, or in any
Prospectus, or any amendment thereof or supplement thereto, or arise out of or are based upon the omission or alleged omission to state therein a material fact necessary to make the statements therein, in the light of the circumstances under which
they were made, not misleading, and will reimburse each such party for any legal or other expenses reasonably incurred by such party in connection with investigating or defending any such action or claim as such expenses are incurred;
provided, however, that: (i) the Company shall not be liable in any such case to the extent that any such loss, claim, damage or liability arises out of or is based upon Holder Information; and (ii) with respect to any untrue statement
or omission of material fact made in any Shelf Registration Statement, or in any Prospectus, the indemnity agreement contained in this Section 5(a) shall not inure to the benefit of the Holder or any person who controls the Holder within the meaning
of either the Securities Act or the Exchange Act from whom the person asserting any such loss, claim, damage or liability purchased the securities concerned, to the extent that any such loss, claim, damage or liability of the Holders occurs under
the circumstance where it shall have been established that: (w) the Company had previously furnished copies of the Prospectus, and any amendments and supplements thereto, to the Holder; (x) delivery of the Prospectus, and any amendment or
supplements thereto, was required by the Securities Act to be made to such person; (y) the untrue statement or omission of a material fact contained in the Prospectus was corrected in amendments or supplements thereto; and (z) there was not sent or
given to such person, at or prior to the written confirmation of the sale of such securities to such person, a copy of such amendments or supplements to the Prospectus. This indemnity agreement will be in addition to any liability that the Company
may otherwise have. This indemnity agreement will not apply to any loss, damage, expense, liability or claim arising from an offer or sale, occurring during a Suspension Period, of Transfer Restricted Securities by a Notice Holder who has previously
received notice from the Company of the commencement of the Suspension Period pursuant to Section 3(c)(vi). 
  
 (b) Each Holder, severally and not jointly, agrees to indemnify and hold harmless the Company, each of its directors and officers and each person, if any,
who controls the Company within the meaning of either the Securities Act or the Exchange Act, to the same extent as the foregoing indemnity from the Company to the Holders and agrees to reimburse each such indemnified party, as incurred, for any
legal or other expenses reasonably incurred by them in connection with investigating or defending any loss, claim, damage, liability or action, but only with reference to Holder Information supplied by such Holder. In no event shall any Holder, its
directors, officers or any person, if any, who controls such Holder be liable or responsible for any amount in excess of the amount by which the total amount received by such Holder with respect to its sale of Transfer Restricted Securities pursuant
to a Shelf Registration Statement 

  

 - 13 - 

 
exceeds: (i) the amount paid by such Holder for such Transfer Restricted Securities; plus (ii) the amount of any damages that such Holder, its directors,
officers or any person who controls such Holder has otherwise been required to pay by reason of such untrue or alleged untrue statement or omission or alleged omission. This indemnity agreement will be in addition to any liability that such Holder
may otherwise have. 
  
 (c) Promptly after receipt by an
indemnified party under this Section 5 of notice of any claim or the commencement of any action or proceeding (including any governmental investigation), such indemnified party will, if a claim for indemnification in respect thereof is to be made
against the indemnifying party under Section 5(a) or 5(b) hereof, notify the indemnifying party in writing of the commencement thereof; but the omission so to notify the indemnifying party will not relieve it from any liability which it may have to
any indemnified party to the extent it is not materially prejudiced as a result thereof and in any event shall not relieve it from any liability which it may have otherwise than on account of this indemnity agreement. In case any such action or
proceeding is brought against any indemnified party, and it notifies the indemnifying party of the commencement thereof, the indemnifying party will be entitled to participate therein (jointly with any other indemnifying party similarly notified),
and to the extent that it may elect, by written notice, delivered to such indemnified party promptly after receiving the aforesaid notice from such indemnified party, to assume the defense thereof, with counsel reasonably satisfactory to such
indemnified party; provided, however, that if the defendants (including any impleaded parties) in any such action include both the indemnified party and the indemnifying party and the indemnified party shall have reasonably concluded
that there may be legal defenses available to it and/or other indemnified parties which are different from or additional to those available to the indemnifying party, the indemnified party or parties shall have the right to select separate counsel
to defend such action on behalf of such indemnified party or parties. Upon receipt of notice from the indemnifying party to such indemnified party of its election so to appoint counsel to defend such action and approval by the indemnified party of
such counsel, the indemnifying party will not be liable to such indemnified party under this Section 5 for any legal or other expenses subsequently incurred by such indemnified party in connection with the defense thereof unless: (i) the indemnified
party shall have employed separate counsel in accordance with the proviso to the preceding sentence (it being understood, however, that the indemnifying party shall not be liable for the expense of more than one separate counsel (in addition to any
local counsel), approved by the Holders in the case of paragraph (a) of this Section 5, representing the indemnified parties under such paragraph (a) who are parties to such action); (ii) the indemnifying party shall not have employed counsel
reasonably satisfactory to the indemnified party to represent the indemnified party within a reasonable time after notice or commencement of the action; (iii) the indemnifying party has authorized the employment of counsel for the indemnified party
at the expense of the indemnifying party; or (iv) the use of counsel chosen by the indemnifying party to represent the indemnified party would present such counsel with a conflict of interest. An indemnifying party will not, without the prior
written consent of the indemnified parties, settle or compromise or consent to the entry of any judgment with respect to any pending or threatened claim, action, suit or proceeding in respect of which indemnification or contribution may be sought
hereunder (whether or not the indemnified parties are actual or potential parties to such claim or action) unless such settlement, compromise or consent includes an unconditional release of each indemnified party from all liability arising out of
such claim, action, suit or proceeding. Subject to the provisions of the immediately following sentence, no indemnifying party shall be liable for 

  

 - 14 - 

 
any settlement, compromise or the consent to the entry of judgment in connection with any such action effected without its written consent, but if settled
with its written consent or if there be a final judgment for the plaintiff in any such action other than a judgment entered with the consent of such indemnified party, the indemnifying party agrees to indemnify and hold harmless any indemnified
party from and against any loss or liability by reason of such settlement or judgment. If at any time an indemnified party shall have requested that an indemnifying party reimburse the indemnified party for reasonable fees and expenses of counsel as
contemplated by this Section 5(c) and to which it would be entitled under Section 5(a) or 5(b) hereof, the indemnifying party agrees that it shall be liable for any settlement of any proceeding effected without its written consent if: (x) such
settlement is entered into more than 45 days after receipt by such indemnifying party of such request for reimbursement, (y) such indemnifying party shall have received notice of the terms of such settlement at least 30 days prior to such settlement
being entered into and (z) such indemnifying party shall not have reimbursed such indemnified party in accordance with such request prior to the date of such settlement. 
  
 (d) In the event that the indemnity provided in paragraph (a) or (b) of this Section 5 is unavailable to or insufficient to
hold harmless an indemnified party for any reason, each indemnifying party agrees to contribute to the aggregate losses, claims, damages and liabilities (including legal or other expenses reasonably incurred in connection with investigating or
defending same) (collectively, “Losses”) to which the indemnified party may be subject in such proportion as is appropriate to reflect the relative benefits received by the Company from the Initial Placement, on the one hand, and a
Holder with respect to the sale by such Holder of Securities or Common Stock, on the other hand; provided, however, that in no case shall an indemnifying party that is a Holder be responsible for any amount in excess of the total price
at which the Transfer Restricted Securities are sold by such Holder to a purchaser. If the allocation provided by the immediately preceding sentence is unavailable for any reason, the Company and such Holder shall contribute in such proportion as is
appropriate to reflect not only such relative benefits but also the relative fault of the Company on the one hand and of such Holder on the other in connection with the statements or omissions which resulted in such Losses, as well as any other
relevant equitable considerations. The relative benefits received by the Company on the one hand and such Holder on the other shall be deemed to be in the same respective proportions as the total net proceeds from the Initial Placement (before
deducting expenses) received by or on behalf of the Company as set forth in the Offering Memorandum, on the one hand, and the total proceeds received by such Holder with respect to its sale of Transfer Restricted Securities under the Shelf
Registration Statement, on the other hand, bear to the total gross proceeds from the Initial Placement. Relative fault shall be determined by reference to, among other things, whether any untrue or any alleged untrue statement of a material fact or
the omission or alleged omission to state a material fact relates to information provided by the Company on the one hand or relates to Holder Information supplied by such Holder, on the other, the intent of the parties and their relative knowledge,
information and opportunity to correct or prevent such untrue statement or omission. The parties agree that it would not be just and equitable if contribution pursuant to this paragraph (d) were determined by pro rata allocation or any other method
of allocation that does not take account of the equitable considerations referred to above. Notwithstanding the provisions of this paragraph (d), no person guilty of fraudulent misrepresentation (within the meaning of Section 11(f) of the Securities
Act) shall be entitled to contribution from any person who was not guilty of such fraudulent misrepresentation. For purposes of this Section 5(d), each person who controls such Holder 

  

 - 15 - 

 
within the meaning of either the Securities Act or the Exchange Act shall have the same rights to contribution as such Holder, and each person who controls
the Company within the meaning of either the Securities Act or the Exchange Act and each officer and director of the Company shall have the same rights to contribution as the Company, subject in each case to the applicable terms and conditions of
this paragraph (d). 
  
 (e) The provisions of this Section 5 will
remain in full force and effect, regardless of any investigation made by or on behalf of any Holder, any underwriter or the Company or any of the officers, directors or controlling persons referred to in Section 5 hereof, and will survive the sale
by a Holder of Transfer Restricted Securities covered by a Shelf Registration Statement. 
  
 6. Rules 144 and 144A. The Company covenants that it shall use its reasonable best efforts to file the reports required to be filed by it under the Securities Act and the Exchange Act in a timely manner so long
as the Transfer Restricted Securities remain outstanding. If at any time the Company is not required to file such reports, it will, upon request of any Holder or beneficial owner of Transfer Restricted Securities, make available such information
necessary to permit sales pursuant to Rule 144A. The Company further covenants that, for as long as any Transfer Restricted Securities remain outstanding, it will take such further action as any Holder of Transfer Restricted Securities may
reasonably request, all to the extent required from time to time to enable such Holder to sell Transfer Restricted Securities without registration under the Securities Act within the limitation of the exemptions provided by Rule 144 and Rule 144A.
Upon the written request of any Holder of Transfer Restricted Securities, the Company shall deliver to such Holder a written statement as to whether it has complied with such requirements. 
  
 7. Miscellaneous. 
  
 (a) No Inconsistent Agreements. The Company has not, as of the date hereof, entered into nor shall it, on or after
the date hereof, enter into, any agreement with respect to its securities that is inconsistent with the rights granted to the Holders herein or otherwise conflicts with the provisions hereof. In addition, the Company shall not grant to any of its
securityholders (other than the Holders of Transfer Restricted Securities in such capacity) the right to include any of its securities in the Shelf Registration Statement provided for in this Agreement other than the Transfer Restricted Securities.

  
 (b) Amendments and Waivers. The provisions of this
Agreement, including the provisions of this sentence, may not be amended, qualified, modified or supplemented, and waivers or consents to departures from the provisions hereof may not be given, unless the Company consents in writing and the Company
has obtained the written consent of at least the majority of the Holders of the then outstanding Transfer Restricted Securities; provided that with respect to any matter that directly or indirectly affects the rights of the Initial Purchasers
hereunder, the Company shall obtain the written consent of the Initial Purchasers against which such amendment, qualification, supplement, waiver or consent is to be effective. Notwithstanding the foregoing (except the foregoing proviso), a waiver
or consent to departure from the provisions hereof with respect to a matter that relates exclusively to the rights of Holders whose Transfer Restricted Securities are being sold pursuant to a Shelf Registration Statement and that does not directly
or indirectly affect the rights of other Holders may be given by the Majority Holders. 
  

 - 16 - 

 (c) Notices. All notices and other communications provided for or permitted hereunder shall be
made in writing by hand-delivery, first-class mail, telecopier, or air courier guaranteeing overnight delivery: 
  
 (i) if to the Initial Purchasers, initially at their address set forth in the Purchase Agreement; 
  
 (ii) if to any other Holder, at the most current address of
such Holder maintained by the Registrar under the Indenture or the registrar of the Common Stock (provided that while the Securities or the Common Stock are in book-entry form, notice to the Trustee shall serve as notice to the Holders), or,
in the case of the Notice Holder, the address set forth in its Notice and Questionnaire; and 
  
 (iii) if to the Company, to: 
  
 Oscient Pharmaceuticals Corporation 
 100
Beaver Street 
 Waltham, MA 02453 
 Facsimile: (781) 893-9535 
 Attn: Chief Financial Officer 
  
 With a copy to: 
  
 Ropes & Gray LLP 
 One International
Place 
 Boston, MA 02110-2624 
 Facsimile: (617) 951-7050 
 Attn: Patrick O’Brien, Esq. 
  
 All such notices and communications shall be deemed to have been duly given when received, if delivered by hand or air courier, and when
sent, if sent by first-class mail or telecopier. 
  
 The Initial
Purchasers or the Company by notice to the other may designate additional or different addresses for subsequent notices or communications. 
  
 (d) Successors and Assigns. This Agreement shall inure to the benefit of and be binding upon the successors and assigns of each of the parties,
including, without the need for an express assignment or any consent by the Company thereto, subsequent Holders. The Company hereby agrees to extend the benefits of this Agreement to any Holder and underwriter and any such Holder and underwriter may
specifically enforce the provisions of this Agreement as if an original party hereto. In the event that any other person shall succeed to the Company under the Indenture, then such successor shall enter into an agreement, in form and substance
reasonably satisfactory to the Initial Purchasers, whereby such successor shall assume all of the Company’s obligations under this Agreement. 
  
 (e) Counterparts. This Agreement may be executed in any number of counterparts and by the parties hereto in separate counterparts, each of which
when so executed shall be 

  

 - 17 - 

 
deemed to be an original and all of which taken together shall constitute one and the same agreement. 
  
 (f) Headings. The headings in this Agreement are for convenience of
reference only and shall not limit or otherwise affect the meaning hereof. 
  
 (g) Governing Law. THIS AGREEMENT SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK APPLICABLE TO AGREEMENTS MADE AND TO BE PERFORMED IN SAID STATE. 
  
 (h) Severability. In the event that any one of more of the provisions
contained herein, or the application thereof in any circumstances, is held invalid, illegal or unenforceable in any respect for any reason, the validity, legality and enforceability of any such provision in every other respect and of the remaining
provisions hereof shall not be in any way impaired or affected thereby, it being intended that all of the rights and privileges of the parties shall be enforceable to the fullest extent permitted by law. 
  
 (i) Securities Held by the Company, Etc. Whenever the consent or
approval of Holders of a specified percentage of principal amount of Securities or the shares of Common Stock issuable upon conversion thereof is required hereunder, Securities or the shares of Common Stock issued upon conversion thereof held by the
Company or its Affiliates (other than subsequent Holders of Securities or the Common Stock issued upon conversion thereof if such subsequent Holders are deemed to be Affiliates solely by reason of their holdings of such Securities) shall not be
counted in determining whether such consent or approval was given by the Holders of such required percentage. 
  
 (j) Termination. This Agreement and the obligations of the parties hereunder shall terminate upon the end of the Shelf Registration Period, except
for any liabilities or obligations under Section 2(e), 4 or 5 to the extent arising prior to the end of the Shelf Registration Period. 
  

 - 18 - 

 Please confirm that the foregoing correctly sets forth the agreement between the Company and you.

  
 Very truly yours, 
  

			
	OSCIENT PHARMACEUTICALS CORPORATION
		
	By:	 	/s/    STEPHEN COHEN
	 Name:
	 	Stephen Cohen
	 Title:
	 	Senior Vice President

  
 The foregoing Agreement is hereby
confirmed and accepted as of the date first above written. 
  

			
	J.P. MORGAN SECURITIES INC.
		
	By:	 	/s/    PHILIP ROSS
	 Name:
	 	Philip Ross
	 Title:
	 	Vice President

  

			
	MERRILL LYNCH, PIERCE, FENNER & SMITH INCORPORATED
		
	By:	 	/s/    OLIVER MOSES
	 Name:
	 	Oliver Moses
	 Title:
	 	Vice President

  

 - 19 -INDENTURE DATED AS OF MAY 10, 2004

 Exhibit 4.4 
  

  
 OSCIENT PHARMACEUTICALS CORPORATION 
  
 as Issuer

  
 and 
  
 U.S. BANK NATIONAL ASSOCIATION 
  
 as Trustee 
  

  
 INDENTURE 
  
 Dated as of May 10, 2004 
  

  
 31⁄2% Senior Convertible Notes Due 2011 
  

  

 TABLE OF CONTENTS 
  

					
	 	  	Page

	 RECITALS OF THE COMPANY
	  	1
		
	 ARTICLE 1
	  	 
	 Definitions and Other Provisions of General Application
	  	1
	 Section 1.01.
	  	 Definitions
	  	1
	 Section 1.02.
	  	 Compliance Certificates and Opinions
	  	10
	 Section 1.03.
	  	 Form of Documents Delivered to Trustee
	  	11
	 Section 1.04.
	  	 Acts of Holders; Record Dates
	  	11
	 Section 1.05.
	  	 Notices, Etc., to Trustee and Company
	  	12
	 Section 1.06.
	  	 Notice to Holders; Waiver
	  	13
	 Section 1.07.
	  	 Conflict with Trust Indenture Act
	  	13
	 Section 1.08.
	  	 Effect of Headings and Table of Contents
	  	13
	 Section 1.09.
	  	 Successors and Assigns
	  	13
	 Section 1.10.
	  	 Severability Clause
	  	13
	 Section 1.11.
	  	 Benefits of Indenture
	  	14
	 Section 1.12.
	  	 Governing Law
	  	14
	 Section 1.13.
	  	 Legal Holiday
	  	14
	 Section 1.14.
	  	 Conforming Amendments and Waivers
	  	14
		
	 ARTICLE 2
	  	 
	 Security Forms
	  	14
	 Section 2.01.
	  	 Forms Generally
	  	14
	 Section 2.02.
	  	 Form of Face of Security
	  	15
	 Section 2.03.
	  	 Form of Reverse of Security
	  	15
	 Section 2.04.
	  	 Form of Trustee’s Certificate of Authentication
	  	15
	 Section 2.05.
	  	 Legend on Restricted Securities
	  	15
		
	 ARTICLE 3
	  	 
	 The Securities
	  	15
	 Section 3.01.
	  	 Title and Terms
	  	15
	 Section 3.02.
	  	 Denominations
	  	16
	 Section 3.03.
	  	 Execution, Authentication, Delivery and Dating
	  	16
	 Section 3.04.
	  	 Temporary Securities
	  	16
	 Section 3.05.
	  	 Registration; Registration of Transfer and Exchange; Restrictions on Transfer
	  	17
	 Section 3.06.
	  	 Mutilated, Destroyed, Lost and Stolen Securities
	  	19
	 Section 3.07.
	  	 Persons Deemed Owners
	  	19
	 Section 3.08.
	  	 Book-Entry Provisions for Global Securities
	  	20
	 Section 3.09.
	  	 Cancellation and Transfer Provisions
	  	21
	 Section 3.10.
	  	 CUSIP Numbers
	  	23

  

					
	 ARTICLE 4
	  	 
	 Satisfaction And Discharge
	  	23
	 Section 4.01.
	  	 Satisfaction and Discharge of Indenture
	  	23
	 Section 4.02.
	  	 Application of Trust Money
	  	24
		
	 ARTICLE 5
	  	 
	 Remedies
	  	24
	 Section 5.01.
	  	 Events of Default
	  	24
	 Section 5.02.
	  	 Acceleration of Maturity; Rescission and Annulment
	  	26
	 Section 5.03.
	  	 Collection of Indebtedness and Suits for Enforcement by Trustee
	  	27
	 Section 5.04.
	  	 Trustee May File Proofs of Claim
	  	27
	 Section 5.05.
	  	 Application of Money Collected
	  	28
	 Section 5.06.
	  	 Limitation on Suits
	  	28
	 Section 5.07.
	  	 Unconditional Right of Holders to Receive Payment
	  	29
	 Section 5.08.
	  	 Restoration of Rights and Remedies
	  	29
	 Section 5.09.
	  	 Rights and Remedies Cumulative
	  	29
	 Section 5.10.
	  	 Delay or Omission Not Waiver
	  	29
	 Section 5.11.
	  	 Control by Holders
	  	30
	 Section 5.12.
	  	 Waiver of Past Defaults
	  	30
	 Section 5.13.
	  	 Undertaking for Costs
	  	30
	 Section 5.14.
	  	 Waiver of Stay or Extension Laws
	  	31
		
	 ARTICLE 6
	  	 
	 The Trustee
	  	31
	 Section 6.01.
	  	 Certain Duties and Responsibilities
	  	31
	 Section 6.02.
	  	 Notice of Defaults
	  	31
	 Section 6.03.
	  	 Certain Rights Of Trustee
	  	31
	 Section 6.04.
	  	 Not Responsible for Recitals
	  	33
	 Section 6.05.
	  	 May Hold Securities
	  	33
	 Section 6.06.
	  	 Money Held in Trust
	  	33
	 Section 6.07.
	  	 Compensation and Reimbursement
	  	33
	 Section 6.08.
	  	 Disqualification; Conflicting Interests
	  	34
	 Section 6.09.
	  	 Corporate Trustee Required; Eligibility
	  	34
	 Section 6.10.
	  	 Resignation and Removal; Appointment of Successor
	  	35
	 Section 6.11.
	  	 Acceptance of Appointment by Successor
	  	36
	 Section 6.12.
	  	 Merger, Conversion, Consolidation or Succession to Business
	  	36
	 Section 6.13.
	  	 Preferential Collection of Claims Against
	  	37
		
	 ARTICLE 7
	  	 
	 Holders’ Lists And Reports By Trustee
	  	37
	 Section 7.01.
	  	 Company to Furnish Trustee Names and Addresses of Holders
	  	37
	 Section 7.02.
	  	 Preservation of Information; Communications to Holders
	  	37
	 Section 7.03.
	  	 Reports By Trustee
	  	37
	 Section 7.04.
	  	 Reports by Company
	  	38

  

 ii 

					
	 ARTICLE 8
	  	 
	 Consolidation, Merger, Conveyance, Transfer Or Lease
	  	38
	 Section 8.01.
	  	 Company May Consolidate, etc., Only on Certain Terms
	  	38
	 Section 8.02.
	  	 Successor Substituted
	  	39
		
	 ARTICLE 9
	  	 
	 Supplemental Indentures
	  	39
	 Section 9.01.
	  	 Supplemental Indentures Without Consent of Holders
	  	39
	 Section 9.02.
	  	 Supplemental Indentures With Consent of Holders
	  	40
	 Section 9.03.
	  	 Execution of Supplemental Indentures
	  	42
	 Section 9.04.
	  	 Effect of Supplemental Indentures
	  	42
	 Section 9.05.
	  	 Conformity with Trust Indenture Act
	  	42
	 Section 9.06.
	  	 Reference in Securities to Supplemental Indentures
	  	42
		
	 ARTICLE 10
	  	 
	 Covenants
	  	43
	 Section 10.01.
	  	 Payments
	  	43
	 Section 10.02.
	  	 Maintenance of Office or Agency
	  	43
	 Section 10.03.
	  	 Money for Security Payments to be Held in Trust
	  	43
	 Section 10.04.
	  	 Statement by Officers as to Default
	  	44
	 Section 10.05.
	  	 Existence
	  	45
	 Section 10.06.
	  	 Reports and Delivery of Certain Information
	  	45
	 Section 10.07.
	  	 Resale of Certain Securities
	  	46
	 Section 10.08.
	  	 Book-Entry System
	  	46
	 Section 10.09.
	  	 Liquidated Damages Under the Registration Rights Agreement
	  	46
	 Section 10.10.
	  	 Information for IRS Filings
	  	46
		
	 ARTICLE 11
	  	 
	 Redemption And Repurchase Upon A Fundamental Change
	  	46
	 Section 11.01.
	  	 Right to Redeem; Notices to Trustee
	  	46
	 Section 11.02.
	  	 Selection of Securities to be Redeemed
	  	47
	 Section 11.03.
	  	 Notice of Redemption
	  	47
	 Section 11.04.
	  	 Effect of Notice of Redemption
	  	48
	 Section 11.05.
	  	 Deposit of Redemption Price
	  	48
	 Section 11.06.
	  	 Securities Redeemed in Part
	  	48
	 Section 11.07.
	  	 Conversion Arrangement on Call for Redemption
	  	48
	 Section 11.08.
	  	 Repurchase of Securities at Option of the Holder Upon Fundamental Change
	  	49
	 Section 11.09.
	  	 Effect of Fundamental Change Repurchase Notice
	  	56
	 Section 11.10.
	  	 Deposit of Fundamental Change Repurchase Price
	  	57
	 Section 11.11.
	  	 Securities Repurchased in Whole or in Part
	  	57
	 Section 11.12.
	  	 Covenant to Comply With Securities Laws Upon Repurchase of Securities
	  	57
	 Section 11.13.
	  	 Repayment to the Company
	  	57

  

 iii 

					
	 ARTICLE 12
	  	 
	 Interest Payments on the Securities
	  	58
	 Section 12.01.
	  	 Interest Rate
	  	58
		
	 ARTICLE 13
	  	 
	 Conversion
	  	58
	 Section 13.01.
	  	 Conversion Privilege
	  	58
	 Section 13.02.
	  	 Conversion Procedure
	  	59
	 Section 13.03.
	  	 Fractional Shares
	  	60
	 Section 13.04.
	  	 Taxes on Conversion
	  	60
	 Section 13.05.
	  	 Company to Provide Stock
	  	61
	 Section 13.06.
	  	 Adjustment of Conversion Rate
	  	61
	 Section 13.07.
	  	 No Adjustment
	  	66
	 Section 13.08.
	  	 Adjustment for Tax Purposes
	  	67
	 Section 13.09.
	  	 Notice of Conversion Rate Adjustment
	  	67
	 Section 13.10.
	  	 Notice of Certain Transactions
	  	67
	 Section 13.11.
	  	 Effect of Reclassification, Consolidation, Merger or Sale on Conversion Privilege
	  	67
	 Section 13.12.
	  	 Trustee’s Disclaimer
	  	68
	 Section 13.13.
	  	 Voluntary Increase
	  	69
	 Section 13.14.
	  	 Company Determination Final
	  	69
		
	 ARTICLE 14
	  	 
	 Collateral Security
	  	69
	 Section 14.01.
	  	 Collateral Security
	  	69
			
	 EXHIBITS:
	  	 	  	 
			
	 Exhibit A
	  	 Form of Face of Security
	  	 
	 Exhibit B
	  	 Form of Reverse of Security
	  	 
	 Exhibit C
	  	 Form of Trustee’s Certificate of Authentication
	  	 
	 Exhibit D
	  	 Fundamental Change Repurchase Notice
	  	 

  

 iv 

 INDENTURE, dated as of May 10, 2004, between Oscient Pharmaceuticals Corporation, a corporation duly
organized and existing under the laws of the Commonwealth of Massachusetts, as Issuer (the “Company”), having its principal office at 100 Beaver Street, Waltham, MA 02453 and U.S. Bank National Association, a national banking
association, as Trustee (the “Trustee”). 
  
 RECITALS OF THE COMPANY 
  
 The Company has duly
authorized the creation of an issue of its 31⁄2% Senior Convertible Notes Due 2011 (each a “Security” and collectively, the “Securities”) of substantially the tenor and amount hereinafter set forth, and to
provide therefor the Company has duly authorized the execution and delivery of this Indenture. 
  
 All things necessary to make the Securities, when executed by the Company and authenticated and delivered hereunder and duly issued by the Company, the valid and legally binding obligations of the Company, and to make
this Indenture a valid and legally binding agreement of the Company, in accordance with the terms of the Securities and the Indenture, have been done. Further, all things necessary to duly authorize the issuance of the Common Stock of the Company
issuable upon the conversion of the Securities, and to duly reserve for issuance the number of shares of Common Stock issuable upon such conversion, have been done. 
  
 The Securities will be partially secured pursuant to the terms of the Pledge Agreement (as defined herein) by Pledged
Securities (as defined herein). 
  
 NOW, THEREFORE, THIS INDENTURE
WITNESSETH: 
  
 For and in consideration of the premises and the
purchases of the Securities by the Holders thereof, it is mutually agreed, for the benefit of the Company and the equal and proportionate benefit of all Holders of the Securities, as follows: 
  
 ARTICLE 1 
 Definitions and Other Provisions of General Application 
  
 Section 1.01. Definitions. For all purposes of this Indenture, except as otherwise expressly provided or unless the context otherwise requires:

  
 (i) the terms defined in this Article have
the meanings assigned to them in this Article and include the plural as well as the singular; 
  
 (ii) all other terms used herein and not otherwise defined that are defined in the Trust Indenture Act, either directly or by reference
therein, have the meanings assigned to them therein; 
  

 (iii) all accounting terms not otherwise defined herein have the meanings assigned to
them in accordance with GAAP; and 
  
 (iv) the
words “herein,” “hereof’ and “hereunder” and other words of similar import refer to this Indenture as a whole and not to any particular Article, Section or other subdivision. 
  
 “Act,” when used with respect to any Holder, has the meaning
specified in Section 1.04. 
  
 “Additional
Securities” has the meaning specified in Section 3.01. 
  
 “Affiliate” of any specified Person means any other Person directly or indirectly controlling or controlled by or under direct or indirect common control with such specified Person. For the purposes of this definition,
“control” when used with respect to any specified Person means the power to direct the management and policies of such Person, directly or indirectly, whether through the ownership of voting securities, by contract or otherwise; and the
terms “controlling” and “controlled” have meanings correlative to the foregoing. 
  
 “Agent Members” has the meaning specified in Section 3.08. 
  
 “Bid Solicitation Agent” means an independent nationally recognized securities dealer selected by the
Company to solicit market bid quotations for the Securities, which initially shall be the Trustee and in no event shall it be an Affiliate of the Company. 
  
 “Board of Directors” means, with respect to any Person, either the board of directors of such Person or any duly authorized committee of
that board. 
  
 “Board Resolution” means, with
respect to any Person, a copy of a resolution certified by the Secretary or an Assistant Secretary of such Person to have been duly adopted by the Board of Directors and to be in full force and effect on the date of such certification, and delivered
to the Trustee. 
  
 “Business Day” means any day
other than a Saturday, a Sunday or a day on which banking institutions in The City of New York or the city in which the Corporate Trust Office is located are authorized or obligated by law, or executive order or governmental decree to be closed.

  
 “Capital Stock” means any and all shares,
interests, participations, rights or other equivalents (however designated) of corporate stock, including, without limitation, with respect to partnerships, partnership interests (whether general or limited) and any other interest or participation
that confers on a Person the right to receive a share of the profits and losses of, or distributions of assets of, such partnership. 
  
 “Cash Buy-Out” has the meaning specified in Section 11.08. 
  

 2 

 “Change of Control Event” means any transaction or event (whether by means of an
exchange offer, liquidation, tender offer, consolidation, merger, combination, reclassification, recapitalization or sale of all or substantially all of the Company’s assets or otherwise) in connection with which all or substantially all of the
Common Stock is exchanged for, converted into, acquired for or constitutes solely the right to receive, consideration which is not all or substantially all common stock or American Depositary Shares that (i) is listed on, or immediately after the
transaction or event will be listed on, a United States national securities exchange, or (ii) is approved, or immediately after the transaction or event will be approved, for quotation on the Nasdaq National Market or any similar United States
system of automated dissemination of quotations of securities prices. 
  
 “Closing Price” with respect to the Company’s Common Stock on any date means the closing price on such date as reported on the National Association of Securities Dealers Automated Quotation System or the principal U.S.
securities exchange on which the Company’s Common Stock is then listed, or, if the Company’s Common Stock is not quoted on the National Association of Securities Dealers Automated Quotation System and is not listed on a U.S. national or
regional exchange or, as reported on the principal other market on which the Company’s Common Stock is then traded. In the absence of such quotations, the Board of Directors of the Company will make a good faith determination of the closing
price. 
  
 “Commission” means the Securities and
Exchange Commission, as from time to time constituted, created under the Exchange Act, or, if at any time after the execution of this instrument such Commission is not existing and performing the duties now assigned to it under the Trust Indenture
Act, then the body performing such duties at such time. 
  
 “Common Stock” means the shares of Common Stock, par value $0.10 per share, of the Company as it exists on the date of this Indenture or any other shares of Capital Stock of the Company into which the Common Stock shall be
reclassified or changed or, in the event of a merger, consolidation or other similar transaction involving the Company that is otherwise permitted hereunder in which the Company is not the surviving corporation, the common stock, common equity
interests, ordinary shares or depositary shares or other certificates representing common equity interests of such surviving corporation or its direct or indirect parent corporation. 
  
 “Company” means the Person named as the “Company” in the first paragraph of this
instrument until a successor Person shall have become such pursuant to the applicable provisions of this Indenture, and thereafter “Company” shall mean such successor Person. 
  
 “Company Request” or “Company Order” means
a written request or order signed in the name of the Company by its Chairman of the Board, its Vice Chairman of the Board, its President or any Vice President, and by its Chief Financial Officer, its Treasurer, an Assistant Treasurer, its Secretary
or an Assistant Secretary, and delivered to the Trustee. 
  
 “Conversion Agent” means the Trustee or such other office or agency designated by the Company with notice provided to the Holders where Securities may be presented for conversion. 
  

 3 

 “Conversion Date” has the meaning specified in Section 13.02(a). 
  
 “Conversion Price” has the meaning specified in Section
13.01(c). 
  
 “Conversion Rate” has the meaning
specified in Section 13.01(c). 
  
 “Corporate Trust
Office” means the office of the Trustee at which the corporate trust business of the Trustee shall, at any particular time, be principally administered, which office is, at the date of this Indenture, located at One Federal Street,
3rd Floor, Boston, Massachusetts 02110. 
  
 “Corporation” means a corporation, association, company, joint-stock company or business trust. 

 
 “Current Market Price” has the meaning specified in
Section 13.06(f). 
  
 “Default” means any event
that is or with the passage of time or the giving of notice or both would become an Event of Default. 
  
 “Determination Date” has the meaning specified in Section 13.06(d). 
  
 “Depositary” means The Depository Trust Company until a successor Depositary shall have become such
pursuant to the applicable provisions of this Indenture, and thereafter “Depositary” shall mean such successor Depositary. 
  
 “Event of Default” has the meaning specified in Section 5.01. 
  
 “Exchange Act” means the U.S. Securities Exchange Act of 1934, as amended. 
  
 “Expiration Date” has the meaning specified in Section
13.06(e). 
  
 “Expiration Time” has the meaning
specified in Section 13.06(e). 
  
 “Fundamental
Change” means any transaction or event resulting in either a Change of Control Event or a Termination of Trading. 
  
 “Fundamental Change Company Notice” has the meaning specified in Section 11.08. 
  
 “Fundamental Change Repurchase Date” has the meaning
specified in Section 11.08. 
  
 “Fundamental Change
Repurchase Notice” has the meaning specified in Section 11.08. 
  
 “Fundamental Change Repurchase Price” has the meaning specified in the Securities. 
  

 4 

 “GAAP” means generally accepted accounting principles set forth in the opinions and
pronouncements of the Accounting Principles Board of the American Institute of Certified Public Accountants and statements and pronouncements of the Financial Accounting Standards Board or in such other statements by such other entity as have been
approved by a significant segment of the accounting profession, in each case, as in effect in the United States on the date hereof. 
  
 “Global Security” means a Security in global form registered in the Security Register in the name of a Depositary or a nominee thereof.

  
 “Government Obligations” means (A) securities
that are (i) direct obligations of the United States of America, for the payment of which the full faith and credit of the United States is pledged or (ii) obligations of a Person controlled or supervised by or acting as an agency or instrumentality
of the United States, the payment of which is unconditionally guaranteed as a full faith and credit obligation by the United States, which, in either case, are not callable or redeemable at the option of the issuer thereof at any time prior to the
stated maturity thereof, or (B) any mutual fund that has at least 95% of its assets continuously invested in investments of the type described in clause (A) above and has the highest rating attainable by Moody’s Investor Services and Standard
& Poor’s Ratings Services, and shall also include a depository receipt issued by a bank or trust company as custodian with respect to any such Government Obligation or a specific payment of interest on or principal of any such Government
Obligation held by such custodian for the account of the holder of a depository receipt; provided that (except as required by law) such custodian is not authorized to make any deduction from the amount payable to the holder of such depository
receipt from any amount received by the custodian in respect of the Government Obligation for the specific payment of interest on or principal of the Government Obligation evidenced by such depository receipt. 
  
 “Holder” or “Securityholder” means a Person
in whose name a Security is registered in the Security Register. 
  
 “Indenture” means this instrument as originally executed or as it may from time to time be supplemented or amended by one or more indentures supplemental hereto entered into pursuant to the applicable provisions hereof,
including, for all purposes of this instrument and any such supplemental indenture, the provisions of the Trust Indenture Act that are deemed to be a part of and govern this instrument and any such supplemental indenture, respectively. 

 
 “Initial Purchaser” means Smithfield Fiduciary LLC.

  
 “Interest Payment Date” means April 15 and
October 15 of each year, commencing October 15, 2004. 
  
 “Investment Company Act” means the Investment Company Act of 1940 and any statute successor thereto, in each case as amended from time to time. 
  
 “Issue Date” means the date the Securities are originally issued as set forth on the face of the Security
under this Indenture. 
  

 5 

 “Liquidated Damages” shall mean the Liquidated Damages as defined in the Registration
Rights Agreement. 
  
 “Make-Whole Premium” has
the meaning specified in Section 11.08. 
  
 “Maturity,” when used with respect to any Security, means the date on which the principal, Repurchase Price or Fundamental Change of such Security becomes due and payable as therein or herein provided, whether at the Stated
Maturity, on a Redemption Date or Fundamental Change Repurchase Date, or by declaration of acceleration or otherwise. 
  
 “Notice of Conversion” has the meaning specified in Section 13.02. 
  
 “Notice of Default” has the meaning specified in Section 5.01. 
  
 “Officers’ Certificate” means a certificate signed by
the Chairman of the Board, the President or any Vice President, and by the Treasurer, an Assistant Treasurer, the Secretary or an Assistant Secretary, of the Company, and delivered to the Trustee. One of the officers signing an Officers’
Certificate given pursuant to Section 10.04 shall be the principal executive, financial or accounting officer of the Company. 
  
 “Opinion of Counsel” means a written opinion of counsel, who may be external or in-house counsel for the Company. 
  
 “Outstanding,” when used with respect to Securities, means,
as of the date of determination, all Securities theretofore authenticated and delivered under this Indenture, except: 
  
 (i) Securities theretofore cancelled by the Trustee or delivered to the Trustee for cancellation; 
  
 (ii) Securities, or portions thereof, for whose payment or
redemption money in the necessary amount has been theretofore deposited with the Trustee or any Paying Agent (other than the Company) in trust or set aside and segregated in trust by the Company (if the Company shall act as its own Paying Agent) for
the Holders of such Securities; provided that if such Securities are to be redeemed prior to the maturity thereof, notice of such redemption shall have been given to the Holders as herein provided, or provision satisfactory to a Responsible Officer
of the Trustee shall have been made for giving such notice; and 
  
 (iii) Securities that have been paid or in exchange for or in lieu of which other Securities have been authenticated and delivered pursuant to this Indenture; 
  
 provided, however, that, in determining whether the Holders of the requisite Principal Amount
of the Outstanding Securities have given any request, demand, authorization, direction, notice, consent or waiver hereunder, Securities owned by the Company or any other obligor upon the 

  

 6 

 
Securities or any Affiliate of the Company or of such other obligor shall be disregarded and deemed not to be Outstanding, except that, in determining
whether the Trustee shall be protected in relying upon any such request, demand, authorization, direction, notice, consent or waiver, only Securities which a Responsible Officer of the Trustee actually knows to be so owned shall be so disregarded.
Securities so owned which have been pledged in good faith may be regarded as Outstanding if the pledgee establishes to the satisfaction of the Trustee the pledgee’s right so to act with respect to such Securities and that the pledgee is not the
Company or any other obligor upon the Securities or any Affiliate of the Company or of such other obligor. 
  
 “Paying Agent” means any Person (including the Company) authorized by the Company to pay the principal of, interest and Liquidated
Damages on the Redemption Price or Fundamental Change Repurchase Price of, any Securities on behalf of the Company. The Trustee shall initially be the Paying Agent. 
  
 “Person” means any individual, corporation, partnership, limited liability company, joint venture, trust,
unincorporated organization or government or any agency or political subdivision thereof. 
  
 “Physical Securities” means permanent certificated Securities in registered form issued in denomination of $1,000 Principal Amount and integral multiples thereof. 
  
 “Pledge Account” means an account established by the Pledged
Securities Intermediary pursuant to the terms of the Pledge Agreement for the deposit of the Pledged Securities purchased by the Company. 
  
 “Pledge Agreement” means the Pledge Agreement, dated as of the date hereof, by and among the Company, the Trustee and the Pledged
Securities Intermediary, as such agreement may be amended, restated, supplemented or otherwise modified from time to time. 
  
 “Pledged Securities” means the Government Obligations to be purchased by the Company and held in the Pledged Account in accordance with
the Pledge Agreement. 
  
 “Pledged Securities
Intermediary” means, initially, U.S. Bank National Association, as securities intermediary under the Pledge Agreement. 
  
 “Principal Amount” of a Security means the Principal Amount as set forth on the face of the Security. 
  
 “Purchase Agreement” means the Purchase Agreement, dated as
of May 25, 2004, entered into by the Company and the Initial Purchaser in connection with the sale of the Securities. 
  
 “Purchased Shares” has the meaning specified in Section 13.06(e). 
  

 7 

 “Qualified Institutional Buyer” or “QIB” shall have the meaning
specified in Rule 144A. 
  
 “Record Date” for the
interest payable on any Interest Payment Date means each April 1 and October 1 (whether or not a Business Day) next preceding such Interest Payment Date. 
  
 “Redemption Date” shall mean the date specified for redemption of the Securities in accordance with the terms of the Securities and
Article 11 hereof. 
  
 “Redemption Price” has the
meaning specified in the Securities. 
  
 “Registration
Rights Agreement” means the Registration Rights Agreement, dated as of May 25, 2004, between the Company and the Initial Purchaser, for the benefit of itself and the Holders, as the same may be amended or modified from time to time in
accordance with the terms thereof and any like Registration Rights Agreement that may be entered into between the Company and The Tail Wind Fund Ltd. upon The Tail Wind Fund Ltd.’s purchase of Securities as contemplated by Section 3.01 hereof.

  
 “Resale Registration Statement” means a
registration statement under the Securities Act registering the Securities for resale pursuant to the terms of the Registration Rights Agreement. 
  
 “Responsible Officer” means any officer of the Trustee within the Corporate Trust Office of the Trustee with direct responsibility for
the administration of this Indenture and also, with respect to a particular matter, any other officer of the Trustee to whom such matter is referred because of such officer’s knowledge and familiarity with the particular subject. 
  
 “Restricted Global Security” means a Global Security
representing Restricted Securities. 
  
 “Restricted
Security” or “Restricted Securities” has the meaning specified in Section 2.05. 
  
 “Rights Plan” has the meaning specified in Section 13.06(c). 
  
 “Rule 144” means Rule 144 under the Securities Act (including any successor rule thereto), as the same may
be amended from time to time. 
  
 “Rule 144A”
means Rule 144A under the Securities Act (including any successor rule thereto), as the same may be amended from time to time. 
  
 “Rule 144A Information” has the meaning specified in the Securities. 
  
 “Securities Act” means the U.S. Securities Act of 1933, as amended, and the rules and regulations of the
Commission promulgated thereunder. 
  

 8 

 “Security” or “Securities” has the meaning specified in the first
paragraph of the Recitals of the Company. 
  
 “Security
Register” and “Security Registrar” have the respective meanings specified in Section 3.05. 
  
 “Stated Maturity,” when used with respect to any Security, means the date specified in such Security as the fixed date on which an amount
equal to the principal amount of such Security together with accrued and unpaid interest and Liquidated Damages, if any, is due and payable. 
  
 “Subsidiary” means a corporation more than 50% of the outstanding voting stock of which is owned, directly or indirectly, by the Company
or by one or more other Subsidiaries. For the purposes of this definition, “voting stock” means stock which ordinarily has voting power for the election of directors, whether at all times or only so long as no senior class of stock has
such voting power by reason of any contingency. 
  
 “Surviving Entity” has the meaning specified in Section 8.01. 
  
 “Termination of Trading” means that the Company’s Common Stock or other common stock into which the Securities are convertible is neither listed for trading on a United States national securities
exchange nor approved for listing on the Nasdaq National Market or any similar United States system of automated dissemination of quotations of securities prices, and no America Depositary Shares or similar instruments for such common stock are so
listed or approved for listing in the United States. 
  
 “Trading Day” means (x) if the applicable security is quoted on the Nasdaq National Market System or Nasdaq SmallCap Market, a day on which trades may be made on thereon or (y) if the applicable security is listed or
admitted for trading on the New York Stock Exchange or another national security exchange, a day on which the New York Stock Exchange or such other national security exchange is open for business or (z) if the applicable security is not so listed,
admitted for trading or quoted, any Business Day. 
  
 “Trading Price,” for purposes of calculating the Make-Whole Premium, on any date of determination means the average of the secondary market bid quotations per Security obtained by the Trustee for $2,000,000 principal amount
of the Securities at approximately 3:30 p.m. New York City time, on such determination date from two independent nationally recognized securities dealers select by the Company, which may include the Initial Purchaser, provided that if at least two
such bids cannot reasonably be obtained by the Trustee, but one such bid can reasonably be obtained by the Trustee, then one bid will be used. If the Trustee cannot reasonably obtain at least one bid for $2,000,000 principal amount of the Securities
from a nationally recognized securities dealer or in the Company’s reasonable judgment, the bid quotations are not indicative of the secondary market value of the Securities, then the “Trading Price” of the Securities will be deemed
to be less than 98% of the applicable conversion rate of the Securities multiplied by the Closing Price of the Common Stock on such determination date. 
  

 9 

 “transfer,” for purposes of Section 3.05, has the meaning specified in Section 3.05.

  
 “Transfer Restricted Security” means a
Security required to bear the restricted legend set forth in the form of Security set forth as Exhibit A attached hereto. 
  
 “Trigger Event” has the meaning specified in Section 13.06(c). 
  
 “Triggering Distribution” has the meaning specified in Section 13.06(d). 
  
 “Trust Indenture Act” means the Trust Indenture Act of 1939
as in effect on the date as of which this Indenture was executed; provided, however, that in the event the Trust Indenture Act of 1939 is amended after such date, “Trust Indenture Act” means, to the extent required by any such amendment,
the Trust Indenture Act of 1939 as so amended. 
  
 “Trustee” means the Person named as the “Trustee” in the first paragraph of this instrument until a successor Trustee shall have become such pursuant to the applicable provisions of this Indenture, and
thereafter “Trustee” shall mean such successor Trustee. 
  
 “United States” means the United States of America (including the States and the District of Columbia), its territories, its possessions and other areas subject to its jurisdiction (its
“possessions” including Puerto Rico, the U.S. Virgin Islands, Guam, American Samoa, Wake Island and the Northern Mariana Islands). 
  
 “Vice President,” when used with respect to the Company or the Trustee, means any vice president, whether or not designated by a number
or a word or words added before or after the title “vice president.” 
  
 Section 1.02. Compliance Certificates and Opinions. Upon any application or request by the Company to the Trustee to take any action under any provision of this Indenture, the Company shall furnish to the
Trustee such certificates and opinions as may be required under the Trust Indenture Act. Each such certificate or opinion shall be given in the form of an Officers’ Certificate, if to be given by an officer of the Company, or an Opinion of
Counsel, if to be given by counsel, and shall comply with the requirements of the Trust Indenture Act and any other requirement set forth in this Indenture. 
  
 Every certificate or opinion with respect to compliance with a condition or covenant provided for in this Indenture shall include: 
  
 (a) a statement that each individual signing such
certificate or opinion has read such covenant or condition and the definitions herein relating thereto; 
  
 (b) a brief statement as to the nature and scope of the examination or investigation upon which the statements or opinions contained in
such certificate or opinion are based; 
  

 10 

 (c) a statement that, in the opinion of each such individual, such individual has made
such examination or investigation as is necessary to enable such individual to express an informed opinion as to whether or not such covenant or condition has been complied with; and 
  
 (d) a statement as to whether, in the opinion of each such individual, such condition or covenant has been
complied with. 
  
 Section 1.03. Form of Documents Delivered to
Trustee. In any case where several matters are required to be certified by, or covered by an opinion of, any specified Person, it is not necessary that all such matters be certified by, or covered by the opinion of, only one such Person, or that
they be so certified or covered by only one document, but one such Person may certify or give an opinion with respect to some matters and one or more other such Persons as to other matters, and any such Person may certify or give an opinion as to
such matters in one or several documents. 
  
 Any certificate or
opinion of an officer of the Company may be based, insofar as it relates to legal matters, upon a certificate or opinion of, or representations by, counsel, unless such officer knows, or in the exercise of reasonable care should know, that the
certificate or opinion or representations with respect to the matters upon which his certificate or opinion is based are erroneous. Any such certificate or Opinion of Counsel may be based, insofar as it relates to factual matters, upon a certificate
or opinion of, or representations by, an officer or officers of the Company stating that the information with respect to such factual matters is in the possession of the Company, unless such counsel knows, or in the exercise of reasonable care
should know, that the certificate or opinion or representations with respect to such matters are erroneous. 
  
 Where any Person is required to make, give or execute two or more applications, requests, consents, certificates, statements, opinions or other
instruments under this Indenture, they may, but need not, be consolidated and form one instrument. 
  
 Section 1.04. Acts of Holders; Record Dates. (a) Any request, demand, authorization, direction, notice, consent, waiver or other action provided by
this Indenture to be given or taken by Holders may be embodied in and evidenced by one or more instruments of substantially similar tenor signed by such Holders in person or by agent duly appointed in writing and, except as herein otherwise
expressly provided, such action shall become effective when such instrument or instruments are delivered to the Trustee and, where it is hereby expressly required, to the Company. Such instrument or instruments (and the action embodied therein and
evidenced thereby) are herein sometimes referred to as an “Act” of the Holders signing such instrument or instruments. Proof of execution of any such instrument or of a writing appointing any such agent shall be sufficient for any purpose
of this Indenture and (subject to Section 6.01) conclusive in favor of the Trustee and the Company, if made in the manner provided in this Section. 
  
 (b) The fact and date of the execution by any Person of any such instrument or writing may be proved by the affidavit of a witness of such
execution or by a 

  

 11 

 
certificate of a notary public or other officer authorized by law to take acknowledgments of deeds, certifying that the individual signing such instrument or
writing acknowledged to him the execution thereof. Where such execution is by a signer acting in a capacity other than his individual capacity, such certificate or affidavit shall also constitute sufficient proof of his authority. The fact and date
of the execution of any such instrument or writing, or the authority of the Person executing the same, may also be proved in any other manner which the Trustee reasonably deems sufficient. 
  
 (c) The Company may, in the circumstances permitted by the
Trust Indenture Act, fix any day as the record date for the purpose of determining the Holders entitled to give or take any request, demand, authorization, direction, notice, consent, waiver or other action, or to vote on any action, authorized or
permitted to be given or taken by Holders. If not set by the Company prior to the first solicitation of a Holder made by any Person in respect of any such action, or, in the case of any such vote, prior to such vote, the record date for any such
action or vote shall be the 30th day (or, if later, the date of the most recent list of Holders required to be provided pursuant to Section 7.01) prior to such first solicitation or vote, as the case may be. With regard to any record date, only the
Holders on such date (or their duly designated proxies) shall be entitled to give or take, or vote on, the relevant action. 
  
 (d) The ownership of Securities shall be proved by the Security Register. 
  
 (e) Any request, demand, authorization, direction, notice, consent, waiver or other Act of the Holder of any
Security shall bind every future Holder of the same Security and the Holder of every Security issued upon the registration of transfer thereof or in exchange therefor or in lieu thereof in respect of anything done, omitted or suffered to be done by
the Trustee or the Company in reliance thereon, whether or not notation of such action is made upon such Security. 
  
 Section 1.05. Notices, Etc., to Trustee and Company. Any request, demand, authorization, direction, notice, consent, waiver or Act of Holders or
other document provided or permitted by this Indenture to be made upon, given or furnished to, or filed with: 
  
 (i) the Trustee by any Holder or by the Company shall be sufficient for every purpose hereunder if made, given, furnished or filed in
writing to or with the Trustee at its Corporate Trust Office; or 
  
 (ii) the Company by the Trustee or by any Holder shall be sufficient for every purpose hereunder (unless otherwise herein expressly provided) if in writing and mailed, first-class postage prepaid, to the Company
addressed to it at the address of its principal office specified in the first paragraph of this instrument or at any other address previously furnished in writing to the Trustee by the Company, Attention: Secretary. 
  

 12 

 Section 1.06. Notice to Holders; Waiver. Where this Indenture provides for notice to Holders of
any event, such notice shall be sufficiently given (unless otherwise herein expressly provided) if in writing and mailed, first-class postage prepaid, to each Holder affected by such event, at such Holder’s address as it appears in the Security
Register, not later than the latest date (if any), and not earlier than the earliest date (if any), prescribed for the giving of such notice. In any case where notice to Holders is given by mail, neither the failure to mail such notice, nor any
defect in any notice so mailed, to any particular Holder shall affect the sufficiency of such notice with respect to other Holders. Where this Indenture provides for notice in any manner, such notice may be waived in writing by the Person entitled
to receive such notice, either before or after the event, and such waiver shall be the equivalent of such notice. Waivers of notice by Holders shall be filed with the Trustee, but such filing shall not be a condition precedent to the validity of any
action taken in reliance upon such waiver. 
  
 In case by reason
of the suspension of regular mail service or by reason of any other cause it shall be impracticable to give such notice by mail, then such notification as shall be made with the approval of the Trustee shall constitute a sufficient notification for
every purpose hereunder. 
  
 Whenever under this Indenture the
Trustee is required to provide any notice by mail, in all cases the Trustee may alternatively provide notice by overnight courier or by telefacsimile, with confirmation of transmission. 
  
 Section 1.07. Conflict with Trust Indenture Act. If any provision hereof limits, qualifies or conflicts with a
provision of the Trust Indenture Act that is required hereunder to be a part of and govern this Indenture, the latter provision shall control. If any provision of this Indenture modifies or excludes any provision of the Trust Indenture Act that may
be so modified or excluded, the latter provision shall be deemed to apply to this Indenture as so modified or to be excluded, as the case may be. 
  
 Section 1.08. Effect of Headings and Table of Contents. The Article and Section headings herein and the Table of Contents are for convenience only
and shall not affect the construction hereof, and all Article and Section references are to Articles and Sections, respectively, of this Indenture unless otherwise expressly stated. 
  
 Section 1.09. Successors and Assigns. All covenants and agreements in this Indenture by the Company shall bind its
successors and assigns, whether so expressed or not. 
  
 Section
1.10. Severability Clause. In case any provision in this Indenture or in the Securities shall be invalid, illegal or unenforceable, the validity, legality and enforceability of the remaining provisions shall not in any way be affected or
impaired thereby. 
  

 13 

 Section 1.11. Benefits of Indenture. Nothing in this Indenture or in the Securities, express or
implied, shall give to any Person, other than the parties hereto and their respective successors hereunder and the Holders of Securities, any benefit or any legal or equitable right, remedy or claim under this Indenture. 
  
 Section 1.12. Governing Law. This Indenture and the Securities shall
be governed by and construed in accordance with the laws of the State of New York. 
  
 Section 1.13. Legal Holiday. In any case where any Interest Payment Date or Stated Maturity of any Security shall not be a Business Day, then (notwithstanding any other provision of this Indenture or of the
Securities) payment of interest or principal need not be made on such date, but may be made on the next succeeding Business Day with the same force and effect as if made on the Interest Payment Date or at the Stated Maturity; provided, that no
interest shall accrue with respect to such payment for the period from and after such Interest Payment Date or Stated Maturity, as the case may be. 
  
 Section 1.14. Conforming Amendments and Waivers. Notwithstanding the provisions of Article 9 hereof, to the extent that any provision of the
Indenture dated as of May 10, 2004 between the Company and the Trustee with respect to an initial aggregate principal amount of $143,750,000 of the Company’s 31⁄2% Senior Convertible Notes due 2011 is amended or waived in accordance with the
terms of such Indenture, the terms of this Indenture shall be amended or waived in the same manner and to the same extent and the Trustee is expressly authorized to take all such actions as are necessary to effect any such amendment or waiver of
this Indenture. 
  
 ARTICLE 2 
 Security Forms 
  
 Section 2.01. Forms Generally. The Securities and the Trustee’s certificates of authentication shall be in substantially the forms set forth
in this Article, with such appropriate insertions, omissions, substitutions and other variations as are required or permitted by this Indenture, and may have such letters, numbers or other marks of identification and such legends or endorsements
placed thereon as may be required to comply with the rules of any securities exchange or Depositary therefor, the Internal Revenue Code of 1986, as amended, and regulations thereunder, or as may, consistently herewith, be determined by the officers
executing such Securities, as evidenced by their execution thereof. 
  
 The Securities shall initially be issued in the form of permanent Global Securities in registered form in substantially the form set forth in this Article. The aggregate Principal Amount of the Global Securities may from time to time be
increased or decreased by adjustments made on the records of the Trustee, as custodian for the Depositary, as hereinafter provided. 
  

 14 

 Section 2.02. Form of Face of Security. The face of each Security shall be substantially in the
form of Exhibit A attached hereto. 
  
 Section 2.03.
Form of Reverse of Security. The reverse of each Security shall be substantially in the form of Exhibit B attached hereto. 
  
 Section 2.04. Form of Trustee’s Certificate of Authentication. No Security shall be entitled to any benefit under this Indenture or be valid
or obligatory for any purpose unless there appears on such Security a certificate of authentication substantially in the form of Exhibit C attached hereto. 
  
 Section 2.05. Legend on Restricted Securities. During the period beginning on the Issue Date and ending on the date
two years from such date, any Security, including any Security issued in exchange therefor or in lieu thereof, shall be deemed a “Restricted Security” and shall be subject to the restrictions on transfer provided in the legends set
forth on the face of the form of Security attached hereto as Exhibit A; provided, however, that the term “Restricted Security” shall not include any Securities as to which restrictions have been terminated in accordance with
Section 3.05. All Securities shall bear the applicable legends set forth on the face of the form of Security attached hereto as Exhibit A. Except as provided in Section 3.05 and Section 3.09, the Trustee shall not issue any unlegended
Security until it has received an Officers’ Certificate from the Company directing it to do so. 
  
 ARTICLE 3 
 The Securities 
  
 Section 3.01. Title and Terms. The aggregate Principal Amount of Securities that may be authenticated and delivered
under this Indenture is initially limited to $6,000,000 (subject to increase by up to $6,000,000 to the extent of the Initial Purchaser’s and The Tail Wind Fund Ltd.’s rights (if any) to purchase additional Securities (the “Additional
Securities”)), except for Securities authenticated and delivered upon registration or transfer of, or in exchange for, or in lieu of, other Securities pursuant to Section 3.04, 3.05, 3.06, 9.06 or 11.04. 
  
 The Securities shall be known and designated as the “31⁄2% Senior
Convertible Notes Due 2011” of the Company. The Principal Amount shall be payable at the Stated Maturity. 
  
 The Principal Amount and accrued interest and Liquidated Damages, if any, on the Securities shall be payable at the office or agency of the Company in The
City of New York maintained for such purpose and at any other office or agency maintained by the Company for such purpose; provided, however, that at the option of the Company payments may be made by wire transfer or by check mailed to the address
of the Person entitled thereto as such address shall appear in the Security Register. 
  
 The Securities shall not have the benefit of a sinking fund. 
  

 15 

 The Securities shall not be superior in right of payment to, and shall rank pari passu with, all other
unsecured and unsubordinated indebtedness of the Company, except as set forth in Article 14 hereof. 
  
 Section 3.02. Denominations. The Securities shall be issuable only in registered form without coupons and in denominations of $1,000 and any
integral multiple of $1,000 above that amount. 
  
 Section 3.03.
Execution, Authentication, Delivery and Dating. The Securities shall be executed on behalf of the Company by its Chairman of the Board, its President or one of its Vice Presidents. 
  
 Securities bearing the manual or facsimile signatures of individuals who were at any time the proper officers of the Company
shall bind the Company, notwithstanding that such individuals or any of them have ceased to hold such offices prior to the authentication and delivery of such Securities or did not hold such offices at the date of such Securities. 
  
 At any time and from time to time after the execution and delivery of this
Indenture, the Company may deliver Securities executed by the Company to the Trustee for authentication, together with a Company Order for the authentication and delivery of such Securities. The Company Order shall specify the amount of Securities
to be authenticated, and shall further specify the amount of such Securities to be issued as a Global Security or as Physical Securities. The Trustee in accordance with such Company Order shall authenticate and deliver such Securities as in this
Indenture provided and not otherwise. 
  
 Each Security shall be
dated the date of its authentication. 
  
 No Security shall be
entitled to any benefit under this Indenture or be valid or obligatory for any purpose unless there appears on such Security a certificate of authentication substantially in the form provided for herein executed by the Trustee by manual signature,
and such certificate upon any Security shall be conclusive evidence, and the only evidence, that such Security has been duly authenticated and delivered hereunder. 
  
 Section 3.04. Temporary Securities. Pending the preparation of definitive Securities, the Company may execute, and
upon Company Order the Trustee shall authenticate and deliver, temporary Securities which are printed, lithographed, typewritten, mimeographed or otherwise produced, in any authorized denomination, substantially of the tenor of the definitive
Securities in lieu of which they are issued and with such appropriate insertions, omissions, substitutions and other variations as the officers executing such Securities may determine, as evidenced by their execution of such Securities. 

 
 If temporary Securities are issued, the Company will cause definitive
Securities to be prepared without unreasonable delay. After the preparation of definitive Securities, the temporary Securities shall be exchangeable for definitive Securities upon surrender of the 

  

 16 

 
temporary Securities at any office or agency of the Company designated pursuant to Section 10.02, without charge to the Holder. Upon surrender for
cancellation of any one or more temporary Securities the Company shall execute and the Trustee shall authenticate and deliver in exchange therefor a like Principal Amount of definitive Securities of authorized denominations. Until so exchanged, the
temporary Securities shall in all respects be entitled to the same benefits under this Indenture as definitive Securities. 
  
 Section 3.05. Registration; Registration of Transfer and Exchange; Restrictions on Transfer. (a) The Company shall cause to be kept at the
Corporate Trust Office of the Trustee a register (the register maintained in such office and in any other office or agency designated pursuant to Section 10.02 being herein sometimes collectively referred to as the “Security
Register”) in which, subject to such reasonable regulations as it may prescribe, the Company shall provide for the registration of Securities and of transfers of Securities. The Trustee is hereby appointed “Security Registrar”
(the “Security Registrar”) for the purpose of registering Securities and transfers of Securities as herein provided. 
  
 Upon surrender for registration of transfer of any Security at an office or agency of the Company designated pursuant to Section 10.02 for such purpose,
the Company shall execute, and the Trustee shall authenticate and deliver, in the name of the designated transferee or transferees, one or more new Securities of any authorized denominations and of a like aggregate Principal Amount and tenor, each
such Security bearing such restrictive legends as may be required by this Indenture (including Sections 2.02, 2.05 and 3.09). 
  
 At the option of the Holder and subject to the other provisions of this Section 3.05 and to Section 3.09, Securities may be exchanged for other Securities
of any authorized denominations and of a like aggregate Principal Amount and tenor, upon surrender of the Securities to be exchanged at such office or agency. Whenever any Securities are so surrendered for exchange, the Company shall execute, and
the Trustee shall authenticate and deliver, the Securities which the Holder making the exchange is entitled to receive. 
  
 All Securities issued upon any registration of transfer or exchange of Securities shall be the valid obligations of the Company, evidencing the same debt,
and entitled to the same benefits under this Indenture, as the Securities surrendered upon such registration of transfer or exchange. 
  
 Every Security presented or surrendered for registration of transfer or for exchange shall (if so required by the Company or the Trustee) be duly
endorsed, or be accompanied by a written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed, by the Holder thereof or his attorney duly authorized in writing. As a condition to the registration of
transfer of any Restricted Securities, the Company or the Trustee may require evidence satisfactory to them as to the compliance with the restrictions set forth in the legend on such securities. 
  
 Except as provided in the following sentence and in Section 3.09, all
Securities originally issued hereunder and all Securities issued upon registration of transfer or exchange or 

  

 17 

 
replacement thereof shall be Restricted Securities and shall bear the legend required by Sections 2.02 and 2.05, unless the Company shall have delivered to
the Trustee (and the Security Registrar, if other than the Trustee) a Company Order stating that the Security is not a Restricted Security and may be issued without such legend thereon. Securities which are issued upon registration of transfer of,
or in exchange for, Securities which are not Restricted Securities shall not be Restricted Securities and shall not bear such legend. 
  
 No service charge shall be made for any registration of transfer or exchange of Securities, but the Company may require payment of a sum sufficient to
cover any tax or other governmental charge that may be imposed in connection with any registration of transfer or exchange of Securities, other than exchanges pursuant to Section 3.04 not involving any transfer. 
  
 The Company shall not be required to exchange or register a transfer of any
Security (i) during the 15-day period immediately preceding the mailing of any notice of redemption of any Security, (ii) after any notice of redemption has been given to Holders, except, where such notice provides that such Security is to be
redeemed only in part, the Company shall be required to exchange or register a transfer of the portion thereof not to be redeemed, (iii) that has been surrendered for conversion or (iv) as to which a Fundamental Change Repurchase Notice has been
delivered and not withdrawn, except, where such Fundamental Change Repurchase Notice provides that such Security is to be purchased only in part, the Company shall be required to exchange or register a transfer of the portion thereof not to be
purchased. 
  
 (b) Beneficial ownership of every
Restricted Security shall be subject to the restrictions on transfer provided in the legends required to be set forth on the face of each Restricted Security pursuant to Sections 2.02 and 2.05, unless such restrictions on transfer shall be
terminated in accordance with this Section 3.05(b) or Section 3.09. The Holder of each Restricted Security, by such Holder’s acceptance thereof, agrees to be bound by such restrictions on transfer. 
  
 The restrictions imposed by this Section 3.05 and by Sections 2.02, 2.05 and
3.09 upon the transferability of any particular Restricted Security shall cease and terminate upon delivery by the Company to the Trustee of an Officers’ Certificate stating that such Restricted Security has been sold pursuant to an effective
Resale Registration Statement under the Securities Act or transferred in compliance with Rule 144 under the Securities Act (or any successor provision thereto). Any Restricted Security as to which the Company has delivered to the Trustee an
Officers’ Certificate that such restrictions on transfer shall have expired in accordance with their terms or shall have terminated may, upon surrender of such Restricted Security for exchange to the Security Registrar in accordance with the
provisions of this Section 3.05, be exchanged for a new Security, of like tenor and aggregate Principal Amount, which shall not bear the restrictive legends required by Sections 2.02 and 2.05. The Company shall inform the Trustee in writing of the
effective date of any Resale Registration Statement registering the Securities under the Securities Act. The Trustee shall not be liable for any action taken or omitted to be taken by it in good faith in accordance with the aforementioned Resale
Registration Statement. 
  

 18 

 As used in the preceding two paragraphs, the term “transfer” encompasses any sale,
pledge, transfer or other disposition of any Restricted Security. 
  
 (c) Neither the Trustee nor any of its agents shall (i) have any duty to monitor compliance with or with respect to any federal or state or other securities or tax laws or (ii) have any duty to obtain documentation
relating to any transfers or exchanges other than as specifically required hereunder. 
  
 Section 3.06. Mutilated, Destroyed, Lost and Stolen Securities. If any mutilated Security is surrendered to the Trustee, the Company shall execute and the Trustee shall authenticate and deliver in exchange
therefor a new Security of like tenor and Principal Amount and bearing a number not contemporaneously outstanding. 
  
 If there shall be delivered to the Company and the Trustee (i) evidence to their satisfaction of the destruction, loss or theft of any Security and (ii)
such security or indemnity as may be required by them to save each of them and any agent of either of them harmless, then, in the absence of notice to the Company or the Trustee that such Security has been acquired by a bona fide purchaser, the
Company shall execute and the Trustee shall authenticate and deliver, in lieu of any such destroyed, lost or stolen Security, a new Security of like tenor and Principal Amount and bearing a number not contemporaneously outstanding. 
  
 In case any such mutilated, destroyed, lost or stolen Security has become or
is about to become due and payable or has been called for redemption in full, the Company in its discretion may, instead of issuing a new Security, pay such Security. 
  
 Upon the issuance of any new Security under this Section 3.06, the Company may require payment by the Holder of a sum
sufficient to cover any tax or other governmental charge that may be imposed in relation thereto and any other expenses (including the fees and expenses of the Trustee) connected therewith. 
  
 Every new Security issued pursuant to this Section 3.06 in lieu of any
destroyed, lost or stolen Security shall constitute an original additional contractual obligation of the Company, whether or not the destroyed, lost or stolen Security shall be at any time enforceable by anyone, and shall be entitled to all the
benefits of this Indenture equally and proportionately with any and all other Securities duly issued hereunder. 
  
 The provisions of this Section are exclusive and shall preclude (to the extent lawful) all other rights and remedies with respect to the replacement or
payment of mutilated, destroyed, lost or stolen Securities. 
  
 Section 3.07. Persons Deemed Owners. Prior to due presentment of a Security for registration of transfer, the Company, the Trustee and any agent of the Company or the Trustee may treat the Person in whose name such Security is
registered as the owner of such Security for the purpose of receiving payment of the principal of and interest and Liquidated Damages, if any, on such Security and for all other purposes whatsoever, 

  

 19 

 
whether or not such Security be overdue, and neither the Company, the Trustee nor any agent of the Company or the Trustee shall be affected by notice to the
contrary. 
  
 Section 3.08. Book-Entry Provisions for Global
Securities. (a) The Global Securities initially shall (i) be registered in the name of the Depositary or the nominee of such Depositary, (ii) be delivered to the Trustee as custodian for the Depositary and (iii) bear legends as set forth on the
face of the form of Security in Section 2.02. 
  
 (b) Members of, or participants in, the Depositary (“Agent Members”) shall have no rights under this Indenture with respect to any Global Security held on their behalf by the Depositary, or the Trustee as its custodian, or
under the Global Security, and the Depositary may be treated by the Company, the Trustee and any agent of the Company or the Trustee as the absolute owner of the Global Security for all purposes whatsoever. Notwithstanding the foregoing, nothing
herein shall prevent the Company, the Trustee or any agent of the Company or the Trustee from giving effect to any written certification, proxy or other authorization furnished by the Depositary or impair, as between the Depositary and its Agent
Members, the operation of customary practices governing the exercise of the rights of any Holder. 
  
 (c) Transfers of the Global Securities shall be limited to transfers in whole, but not in part, to the Depositary, its successors or their
respective nominees. Interests of beneficial owners in a Global Security may be transferred or exchanged, in whole or in part, for Physical Securities in accordance with the rules and procedures of the Depositary and the provisions of Section 3.09.
In addition, Physical Securities shall be transferred to all beneficial owners in exchange for their beneficial interests in the Global Securities if (A) such Depositary has notified the Company (or the Company becomes aware) that the Depositary (i)
is unwilling or unable to continue as Depositary for such Global Security or (ii) has ceased to be a clearing agency registered under the Exchange Act when the Depositary is required to be so registered to act as such Depositary and, in either such
case, no successor Depositary shall have been appointed within 90 days of such notification or of the Company becoming aware of such event; or (B) there shall have occurred and be continuing an Event of Default with respect to such Global Security
and the Outstanding Securities shall have become due and payable pursuant to Section 5.02 and the Trustee requests that Physical Securities be issued; provided that Holders of Physical Securities offered and sold in reliance on Rule 144A shall have
the right, subject to applicable law, to request that such Securities be exchanged for interests in the applicable Global Security. 
  
 (d) In connection with any transfer or exchange of a portion of the beneficial interest in the Global Security to beneficial owners
pursuant to clause (b) of this Section 3.08, the Security Registrar shall (if one or more Physical Securities are to be issued) reflect on its books and records the date and a decrease in the Principal Amount of the Global Security in an amount
equal to the Principal Amount of the beneficial interest in the Global Security to be transferred, and the Company shall execute, and the Trustee shall authenticate and deliver, one or more Physical Securities of like tenor and amount. 

 

 20 

 (e) In connection with the transfer of the entire Global Security to beneficial owners
pursuant to clause (b) of this Section 3.08, the Global Security shall be deemed to be surrendered to the Trustee for cancellation, and the Company shall execute, and the Trustee shall authenticate and deliver, to each beneficial owner identified by
the Depositary in exchange for its beneficial interest in the Global Security, an equal aggregate Principal Amount of Physical Securities of authorized denominations and the same tenor. 
  
 (f) Any Physical Security constituting a Restricted Security delivered in exchange for an interest in the
Global Security pursuant to clause (c) or (d) of this Section 3.08 shall, except as otherwise provided by clause (c) of Section 3.09, bear the legend regarding transfer restrictions applicable to the Physical Securities set forth on the face of the
form of Security in Section 2.02. 
  
 (g) The
Holder of the Global Securities may grant proxies and otherwise authorize any Person, including Agent Members and Persons that may hold interests through Agent Members, to take any action which a Holder is entitled to take under this Indenture or
the Securities. 
  
 (h) The Trustee shall have no
responsibility or obligation to any beneficial owner of a Global Security, a member or, or a participant in the Depositary or other Person with respect to the accuracy of the books or records, or the acts or omissions, of the Depositary or its
nominee or of any participant or member thereof, with respect to any ownership interest in the Securities or with respect to the delivery to any participant, member, beneficial owner or other Person (other than the Depositary) of any notice
(including any notice of redemption) or the payment of any amount, under or with respect to such Securities. All notices and communications to be given to the Holders and all payment to be made to Holders under the Securities shall be given or made
only to or upon the order of the registered Holders (which shall be the Depositary or its nominee in the case of a Global Security). The rights of beneficial owners in any Global Security shall be exercised only through the Depositary subject to the
applicable procedures of the Depositary. The Trustee may rely on information furnished by the Depositary with respect to its members, participants and any beneficial owners. 
  
 Section 3.09. Cancellation and Transfer Provisions. The Company at any time may deliver to the Trustee for
cancellation any Securities previously authenticated and delivered hereunder which the Company may have acquired in any manner whatsoever, and may deliver to the Trustee for cancellation any Securities previously authenticated hereunder which the
Company has not issued and sold. The Trustee shall cancel and dispose of all Securities surrendered for registration of transfer, exchange, payment, purchase, repurchase, redemption, conversion (pursuant to Article 13 hereof) or cancellation in
accordance with its customary practices. If the Company shall acquire any of the Securities, such acquisition shall not operate as a redemption or satisfaction of the indebtedness represented by such Securities unless and until the same are
delivered to the Trustee for cancellation. The Company may not issue new Securities to replace Securities it has paid in full or delivered to the Trustee for cancellation. 
  

 21 

 (a) Transfers to QIBs. The following provisions shall apply with respect to the
registration of any proposed transfer of a Security constituting a Restricted Security to a QIB: 
  
 (i) the Security Registrar shall register the transfer if such transfer is being made by a proposed transferor who has checked the box
provided for on the form of Security stating, or has otherwise advised the Company and the Security Registrar in writing, that the sale has been made in compliance with the provisions of Rule 144A to a transferee who has signed the certification
provided for on the form of Security stating, or has otherwise advised the Company and the Security Registrar in writing, that it is purchasing the Security for its own account or an account with respect to which it exercises sole investment
discretion and that it and any such account is a QIB within the meaning of Rule 144A, and is aware that the sale to it is being made in reliance on Rule 144A and acknowledges that it has received such information regarding the Company as it has
requested pursuant to Rule 144A or has determined not to request such information and that it is aware that the transferor is relying upon its foregoing representations in order to claim the exemption from registration provided by Rule 144A; and

  
 (ii) if the proposed transferee is an Agent
Member, and the Securities to be transferred consist of Physical Securities which after transfer are to be evidenced by an interest in the Global Security, upon receipt by the Security Registrar of instructions given in accordance with the
Depositary’s and the Security Registrar’s procedures, the Security Registrar shall reflect on its books and records the date and an increase in the Principal Amount of the Global Security in an amount equal to the Principal Amount of the
Physical Securities to be transferred, and the Trustee shall cancel the Physical Securities so transferred. 
  
 (b) Private Placement Legend. Upon the registration of transfer, exchange or replacement of Securities not bearing the legends
required by Sections 2.02 and 2.05, the Security Registrar shall deliver Securities that do not bear such legends. Upon the registration of transfer, exchange or replacement of Securities bearing the legends required by Sections 2.02 and 2.05, the
Security Registrar shall deliver only Securities that bear such legends unless there is delivered to the Security Registrar an Opinion of Counsel reasonably satisfactory to the Company and the Trustee to the effect that neither such legend nor the
related restrictions on transfer are required in order to maintain compliance with the provisions of the Securities Act. 
  
 (c) General. By its acceptance of any Security bearing the legends required by Sections 2.02 and 2.05, each Holder of such a
Security acknowledges the restrictions on transfer of such Security set forth in this Indenture and in such legends and agrees that it will transfer such Security only as provided in this Indenture. 
  
 The Security Registrar shall retain, in accordance with its customary
procedures, copies of all letters, notices and other written communications received pursuant to this Section 3.09. The Company shall have the right to inspect and make copies of all such letters, notices or other 

  

 22 

 
written communications at any reasonable time upon the giving of reasonable written notice to the Security Registrar. 
  
 The Trustee shall have no obligation or duty to monitor, determine or inquire
as to compliance with any restrictions on transfer imposed under this Indenture or under applicable law with respect to any transfer of any interest in any Security (including any transfers between or among Depositary participants, members or
beneficial owners in any Global Security) other than to require delivery of such certificates and other documentation or evidence as are expressly required by the terms of this Indenture, and to examine the same to determine substantial compliance
as to form with the express requirements hereof. 
  
 Section 3.10.
CUSIP Numbers. In issuing the Securities, the Company may use “CUSIP” numbers (if then generally in use), and, if so, the Trustee shall use “CUSIP” numbers in notices of redemption as a convenience to Holders; provided
that any such notice may state that no representation is made as to the correctness of such numbers either as printed on the Securities or as contained in any notice of a redemption and that reliance may be placed only on the other identification
numbers printed on the Securities, and any such redemption shall not be affected by any defect in or omission of such numbers. The Company will promptly notify the Trustee of any change in the “CUSIP” numbers. 
  
 ARTICLE 4 
 Satisfaction And Discharge 
  
 Section 4.01. Satisfaction and Discharge of Indenture. This Indenture shall cease to be of further effect (except as to any surviving rights of registration of transfer or exchange of Securities herein
expressly provided for), and the Trustee, on demand of and at the expense of the Company, shall execute proper instruments acknowledging satisfaction and discharge of this Indenture, when 
  
 (a) either 
  
 (i) all Securities theretofore authenticated and delivered
(other than (A) Securities which have been destroyed, lost or stolen and which have been replaced or paid as provided in Section 3.06 and (B) Securities for whose payment money has theretofore been deposited with the Trustee in trust or segregated
and held in trust by the Company and thereafter repaid to the Company or discharged from such trust as provided in Section 10.03) have been delivered to the Trustee for cancellation; or 
  
 (ii) all such Securities not theretofore delivered to the Trustee for cancellation have become due and
payable and the Company has deposited or caused to be deposited with the Trustee as trust funds in trust for the purpose an amount sufficient to pay and discharge the entire indebtedness evidenced by such Securities not theretofore delivered to the
Trustee for cancellation; 
  

 23 

 (b) the Company has paid or caused to be paid all other sums payable hereunder by the
Company; and 
  
 (c) the Company has delivered to
the Trustee an Officers’ Certificate and an Opinion of Counsel, each stating that all conditions precedent herein provided for relating to the satisfaction and discharge of this Indenture have been complied with. 
  
 Notwithstanding the satisfaction and discharge of this Indenture, the
obligations of the Company to the Trustee under Section 6.07 and, if money shall have been deposited with the Trustee pursuant to clause (a)(ii) of Section 4.01, the obligations of the Trustee under Section 4.02 and the last paragraph of Section
10.03 shall survive such satisfaction and discharge. 
  
 Section
4.02. Application of Trust Money. Subject to the provisions of the last paragraph of Section 10.03, all money deposited with the Trustee pursuant to Section 4.01 shall be held in trust and applied by it, in accordance with the provisions of
the Securities and this Indenture, to the payment, either directly or through any Paying Agent (including the Company acting as its own Paying Agent) as the Trustee may determine, to the Persons entitled thereto, of the principal, interest and
Liquidated Damages, if any, for whose payment such money has been deposited with the Trustee. 
  
 ARTICLE 5 
 Remedies 
  

Section 5.01. Events of Default. “Event of Default,” wherever used herein, means any one of the following events (whatever the
reason for such Event of Default and whether it shall be voluntary or involuntary or be effected by operation of law or pursuant to any judgment, decree or order of any court or any order, rule or regulation of any administrative or governmental
body): 
  
 (a) default in the payment of interest
(other than the first six scheduled interest payments up to and including the interest payment due on April 15, 2007) or Liquidated Damages, if any, on any Securities when due and payable and such default continues for a period of 30 days; or

  
 (b) default in the payment of the Principal
Amount, Redemption Price, Fundamental Change Repurchase Price or the first six scheduled interest payments up to and including the interest payment due on April 15, 2007 on any Security when it becomes due and payable; or 
  
 (c) default in the performance of any covenant, agreement or
condition of the Company in this Indenture or the Securities (other than a default specified in clause (a) or (b) above), and such default continues for a period of 60 days after there has been given, by registered or certified mail, to the Company
by the Trustee or to the Company and the Trustee by the Holders of at least 25% in aggregate Principal Amount of the Outstanding Securities a 

  

 24 

 
written notice specifying such default and requiring it to be remedied and stating that such notice is a “Notice of Default” hereunder; or

  
 (d) default in the Company’s obligation
to convert the Securities into shares of its Common Stock upon exercise of a Holder’s conversion rights in accordance with Article 13 hereof and such default continues for a period of 10 days; or 
  
 (e) default by the Company or any Subsidiary in the payment
of the principal or interest on any loan agreement or other instrument under which there may be outstanding, or by which there may be evidenced, any debt for money borrowed in excess of $7.5 million in the aggregate of the Company and any Subsidiary
(other than indebtedness for borrowed money secured only by the real property to which the indebtedness relates and which is non-recourse to the Company or to such Subsidiary), whether such debt now exists or shall hereafter be created, resulting in
such debt becoming or being declared due and payable prior to its stated maturity, and such acceleration shall not have been rescinded or annulled within 30 days after written notice has been received by the Company or such Subsidiary from the
Trustee or by the Trustee, the Company and such Subsidiary by the Holders of at least 25% in Principal Amount of Outstanding Securities; provided that if any time before a judgment or decree has been obtained by the Trustee as hereinafter provided,
such default is remedied or cured by the Company within the applicable cure period, or is waived by the holders of such indebtedness, default under this clause (e) shall be deemed to have been remedied, cured or waived, as the case may be; or

  
 (f) failure by the Company to give the
Fundamental Change Company Notice; or 
  
 (g) the
entry by a court having jurisdiction in the premises of (i) a decree or order for relief in respect of the Company of a voluntary case or proceeding under any applicable Federal or State bankruptcy, insolvency, reorganization or other similar law or
(ii) a decree or order adjudging the Company as bankrupt or insolvent, or approving as properly filed a petition seeking reorganization, arrangement, adjustment or composition of or in respect of the Company under any applicable Federal or State law
or (iii) appointing a custodian, receiver, liquidator, assignee, trustee, sequestrator or other similar official of the Company or of any substantial part of its property, or ordering the winding up or liquidation of its affairs, and the continuance
of any such decree or order for relief or any such other decree or order unstayed and in effect for a period of 60 consecutive days; or 
  
 (h) the commencement by the Company of a voluntary case or proceeding under any applicable Federal or State bankruptcy, insolvency,
reorganization or other similar law or of any other case or proceeding to be adjudicated a bankrupt or insolvent, or the consent by it to the entry of a decree or order for relief in respect of the Company in an involuntary case or proceeding under
any applicable Federal or State bankruptcy, insolvency, reorganization or other similar law or to the commencement of any bankruptcy or insolvency case or proceeding against it, or the filing by it of a petition or answer or consent seeking
reorganization or relief under any applicable Federal or State law, or the consent by it to the 

  

 25 

 
filing of such petition or to the appointment of or taking possession by a custodian, receiver, liquidator, assignee, trustee, sequestrator or other similar
official of the Company or of any substantial part of its property, or the making by it of an assignment for the benefit of creditors, or the admission by it in writing of its inability to pay its debts generally as they become due, or the taking of
corporate action by the Company in furtherance of any such action; or 
  
 (i) the Pledge Agreement shall cease to be in full force and effect or enforceable prior to the expiration thereof in accordance with its terms. 
  
 Section 5.02. Acceleration of Maturity; Rescission and Annulment. (a) If an Event of Default (other than those
specified in clauses (g) and (h) of Section 5.01) occurs and is continuing, then and in every such case the Trustee or the Holders of not less than 25% in aggregate Principal Amount of the Outstanding Securities may declare the Principal Amount plus
accrued and unpaid interest and Liquidated Damages, if any, on all the Outstanding Securities to be due and payable immediately, by a notice in writing to the Company (and to the Trustee if given by Holders), and upon any such declaration such
Principal Amount plus accrued and unpaid interest and Liquidated Damages, if any, shall become immediately due and payable. 
  
 Notwithstanding the foregoing, in the case of an Event of Default specified in clauses (g) and (h) of Section 5.01, the Principal Amount plus accrued and
unpaid interest and Liquidated Damages, if any, on all Outstanding Securities will ipso facto become due and payable without any declaration or other Act on the part of the Trustee or any Holder. 
  
 (b) At any time after such a declaration of acceleration has
been made and before a judgment or decree for payment of the money due has been obtained by the Trustee as hereinafter in this Article 5 provided, the Holders of a majority in aggregate Principal Amount of the Outstanding Securities, by written
notice to the Company and the Trustee, may rescind and annul such declaration and its consequences if such rescission and annulment will not conflict with any judgment or decree of a court of competent jurisdiction and: 
  
 (i) the Company has paid or deposited with the Trustee a sum
sufficient to pay 
  
 all overdue interest on
the Securities, 
  
 the Principal Amount plus
accrued and unpaid interest and Liquidated Damages, if any, Redemption Price or Fundamental Change Repurchase Price, as applicable, on any Securities which have become due otherwise than by such declaration of acceleration, and 
  
 all sums paid or advanced by the Trustee hereunder and the
reasonable compensation, expenses, disbursements and advances 

  

 26 

 
of the Trustee, its agents and counsel and any other amounts due the Trustee under Section 6.07; and 
  
 (ii) all Events of Default, other than the non-payment of
the Principal Amount plus accrued and unpaid interest and Liquidated Damages, if any, on Securities which have become due solely by such declaration of acceleration, have been cured or waived as provided in Section 5.12. 
  
 No such rescission shall affect any subsequent default or impair any right
consequent thereon. 
  
 Section 5.03. Collection of
Indebtedness and Suits for Enforcement by Trustee. The Company covenants that if a default is made in the payment of the Principal Amount plus accrued and unpaid interest and Liquidated Damages, if any, at the Maturity thereof or in the payment
of the Redemption Price or the Fundamental Change Repurchase Price in respect of any Security, the Company will, upon demand of the Trustee, pay to it, for the benefit of the Holders of such Securities, the whole amount then due and payable on such
Securities, and, in addition thereto, such further amount as shall be sufficient to cover the costs and expenses of collection, including the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel.

  
 If an Event of Default occurs and is continuing, the Trustee
may, but shall not be obligated to, pursue any available remedy to collect the payment of the principal amount plus accrued but unpaid interest and Liquidated Damages, if any, on the Securities or to enforce the performance of any provision of the
Securities or this Indenture. The Trustee may maintain a proceeding even if the Trustee does not possess any of the Securities or does not produce any of the Securities in the proceeding. A delay or omission by the Trustee or any Holder in
exercising any right or remedy accruing upon an Event of Default shall not impair the right or remedy or constitute a waiver of, or acquiescence in, the Event of Default. No remedy is exclusive of any other remedy. All available remedies are
cumulative. 
  
 Section 5.04. Trustee May File Proofs of
Claim. In case of any judicial proceeding relative to the Company (or any other obligor upon the Securities), its property or its creditors, the Trustee shall be entitled and empowered, by intervention in such proceeding or otherwise, to take
any and all actions authorized under the Trust Indenture Act in order to have claims of the Holders and the Trustee allowed in any such proceeding. In particular, the Trustee shall be authorized to collect and receive any moneys or other property
payable or deliverable on any such claims and to distribute the same; and any custodian, receiver, assignee, trustee, liquidator, sequestrator or other similar official in any such judicial proceeding is hereby authorized by each Holder to make such
payments to the Trustee and, in the event that the Trustee shall consent to the making of such payments directly to the Holders, to pay to the Trustee any amount due it for the reasonable compensation, expenses, disbursements and advances of the
Trustee, its agents and counsel and any other amounts due the Trustee under Section 6.07. 
  

 27 

 No provision of this Indenture shall be deemed to authorize the Trustee to authorize or consent to or
accept or adopt on behalf of any Holder any plan of reorganization, arrangement, adjustment or composition affecting the Securities or the rights of any Holder thereof or to authorize the Trustee to vote in respect of the claim of any Holder in any
such proceeding. 
  
 The Trustee shall be entitled to participate
as a member of any official committee of creditors of the Company as it deems necessary or advisable. 
  
 Section 5.05. Application of Money Collected. Any money collected by the Trustee pursuant to this Article shall be applied in the following order,
at the date or dates fixed by the Trustee and, in case of the distribution of such money to Holders, upon presentation of the Securities and the notation thereon of the payment if only partially paid and upon surrender thereof if fully paid:

  
 FIRST: To the payment of all amounts due the
Trustee under Section 6.07; 
  
 SECOND: To the
payment of the amounts then due and unpaid on the Securities for the Principal Amount, Redemption Price, Fundamental Change Repurchase Price or interest and Liquidated Damages, if any, as the case may be, in respect of which or for the benefit of
which such money has been collected, ratably, without preference or priority of any kind, according to the amounts due and payable on such Securities; and 
  
 THIRD: To the Company. 
  
 Section 5.06. Limitation on Suits. No Holder of any Security shall have any right to institute any proceeding, judicial or otherwise, with respect
to this Indenture, or for the appointment of a receiver or trustee, or for any other remedy hereunder (other than in the case of an Event of Default specified in clause (a) or (b) of Section 5.01), unless: 
  
 (i) such Holder has previously given written notice to the
Trustee of a continuing Event of Default; 
  
 (ii) the Holders of not less than 25% in aggregate Principal Amount of the Outstanding Securities shall have made written request to the Trustee to institute proceedings in respect of such Event of Default in its own name as Trustee
hereunder; 
  
 (iii) such Holder or Holders have
offered to the Trustee indemnity reasonably satisfactory to it against the costs, expenses and liabilities to be incurred in compliance with such request; 
  
 (iv) the Trustee for 60 days after its receipt of such notice, request and offer of security or indemnity has failed to institute any such
proceeding; and 
  

 28 

 (v) no direction, in the opinion of the Trustee, inconsistent with such written request
has been given to the Trustee during such 60-day period by the Holders of a majority in aggregate Principal Amount of the Outstanding Securities; 
  
 it being understood and intended that no one or more Holders shall have any right in any manner whatever by virtue of, or by availing itself of, any provision of this
Indenture to affect, disturb or prejudice the rights of any other Holders, or to obtain or to seek to obtain priority or preference over any other Holders or to enforce any right under this Indenture, except in the manner herein provided and for the
equal and ratable benefit of all the Holders. 
  
 Section 5.07.
Unconditional Right of Holders to Receive Payment. Notwithstanding any other provision of this Indenture, the right of any Holder to receive payment of the Principal Amount, Redemption Price, Fundamental Change Repurchase Price or interest
and Liquidated Damages, if any, in respect of the Securities held by such Holder, on or after the respective due dates expressed in the Securities or any Redemption Date or Fundamental Change Repurchase Date, as applicable, and to convert the
Securities in accordance with Article 13, or to bring suit for the enforcement of any such payment on or after such respective dates or the right to convert, shall not be impaired or affected adversely without the consent of such Holder. 

 
 Section 5.08. Restoration of Rights and Remedies. If the Trustee or
any Holder has instituted any proceeding to enforce any right or remedy under this Indenture and such proceeding has been discontinued or abandoned for any reason, or has been determined adversely to the Trustee or to such Holder, then and in every
such case, subject to any determination in such proceeding, the Company, the Trustee and the Holders shall be restored severally and respectively to their former positions hereunder and thereafter all rights and remedies of the Trustee and the
Holders shall continue as though no such proceeding had been instituted. 
  
 Section 5.09. Rights and Remedies Cumulative. Except as otherwise provided with respect to the replacement or payment of mutilated, destroyed, lost or stolen Securities in the last paragraph of Section 3.06, no
right or remedy herein conferred upon or reserved to the Trustee or to the Holders is intended to be exclusive of any other right or remedy, and every right and remedy shall, to the extent permitted by law, be cumulative and in addition to every
other right and remedy given hereunder or now or hereafter existing at law or in equity or otherwise. The assertion or employment of any right or remedy hereunder shall not prevent the concurrent assertion or employment of any other appropriate
right or remedy. 
  
 Section 5.10. Delay or Omission Not
Waiver. No delay or omission of the Trustee or of any Holder of any Security to exercise any right or remedy accruing upon any Event of Default shall impair any such right or remedy or constitute a waiver of any such Event of Default or an
acquiescence therein. Every right and remedy given by this Article or by law to the Trustee or to the Holders may be exercised from time to time, and 

  

 29 

 
as often as may be deemed expedient, by the Trustee or by the Holders, as the case may be. 
  
 Section 5.11. Control by Holders. The Holders of a majority in Principal Amount of the Outstanding Securities shall
have the right to direct the time, method and place of conducting any proceeding for any remedy available to the Trustee or exercising any trust or power conferred on the Trustee, provided that: 
  
 (i) such direction shall not be in conflict with any rule of
law or with this Indenture; 
  
 (ii) the Trustee
may take any other action deemed proper by the Trustee which is not inconsistent with such direction; and 
  
 (iii) the Trustee may refuse to follow any direction that may involve the Trustee in personal liability for which the Trustee would not
otherwise be entitled to indemnification pursuant to the terms of this Indenture. 
  
 Section 5.12. Waiver of Past Defaults. The Holders of not less than a majority in Principal Amount of the Outstanding Securities may on behalf of the Holders of all the Securities waive any past Default
hereunder and its consequences, except a Default: 
  
 (i) Described in clause (a) or (b) of Section 5.01; or 
  
 (ii) in respect of a covenant or provision hereof which under Article 9 cannot be modified or amended without the consent of the Holder of each Outstanding Security affected. 
  
 Upon any such waiver, such Default shall cease to exist, and any Event of
Default arising therefrom shall be deemed to have been cured, for every purpose of this Indenture; but no such waiver shall extend to any subsequent or other Default or impair any right consequent thereon. 
  
 Section 5.13. Undertaking for Costs. In any suit for the enforcement
of any right or remedy under this Indenture or in any suit against the Trustee for any action taken or omitted by it as Trustee, in either case in respect of the Securities, a court may require any party litigant in such suit to file an undertaking
to pay the costs of the suit, and the court may assess reasonable costs, including reasonable attorney’s fees, and expenses, against any party litigant in the suit having due regard to the merits and good faith of the claims or defenses made by
the party litigant; but the provisions of this Section 5.13 shall not apply to any suit instituted by the Company, to any suit instituted by the Trustee, to any suit instituted by any Holder, or group of Holders, holding in the aggregate more than
10% in Principal Amount of the Outstanding Securities, or to any suit instituted by any Holder for the enforcement of the payment of the Principal Amount or interest or Liquidated Damages on any Security on or after Maturity of such Security, the
Redemption Price or the Fundamental Change Repurchase Price. 
  

 30 

 Section 5.14. Waiver of Stay or Extension Laws. The Company covenants (to the extent that it may
lawfully do so) that it will not at any time insist upon, or plead, or in any manner whatsoever claim or take the benefit or advantage of, any stay, or extension law wherever enacted, now or at any time hereafter in force, which may affect the
covenants or the performance of this Indenture; and the Company (to the extent that it may lawfully do so) hereby expressly waives all benefit or advantage of any such law and covenants that it will not hinder, delay or impede the execution of any
power herein granted to the Trustee, but will suffer and permit the execution of every such power as though no such law had been enacted. 
  
 ARTICLE 6 
 The Trustee 
  
 Section 6.01. Certain Duties and Responsibilities. The duties and
responsibilities of the Trustee shall be as provided by the Trust Indenture Act. Except during the continuance of an Event of Default, the Trustee undertakes to perform such duties and only such duties as are specifically set forth in this
Indenture, and no implied covenants or obligations shall be read into this Indenture against the Trustee. In case an Event of Default with respect to the Securities has occurred (which has not been cured or waived), the Trustee shall exercise the
rights and powers vested in it by this Indenture, and use the same degree of care and skill in their exercise, as a prudent person would exercise or use under the circumstances in the conduct of such person’s own affairs. Notwithstanding the
foregoing, no provision of this Indenture shall require the Trustee to expend or risk its own funds or otherwise incur any financial liability in the performance of any of its duties hereunder, or in the exercise of any of its rights or powers,
except to the extent the Trustee is entitled to reimbursement hereunder. Whether or not therein expressly so provided, every provision of this Indenture relating to the conduct or affecting the liability of or affording protection to the Trustee
shall be subject to the provisions of this Section 6.01. 
  
 Section 6.02. Notice of Defaults. The Trustee shall give the Holders notice of any Default hereunder within 60 days after the occurrence thereof; provided, that (except in the case of any Default in the payment of Principal Amount or
interest and Liquidated Damages, if any, on any of the Securities, Redemption Price or Fundamental Change Repurchase Price), the Trustee shall be protected in withholding such notice if and so long as a trust committee of directors or trustees
and/or a Responsible Officer of the Trustee in good faith determines that the withholding of such notice is in the interest of the Holders of Securities. 
  
 Section 6.03. Certain Rights Of Trustee. Subject to the provisions of Section 6.01: 
  
 (a) the Trustee may conclusively rely and shall be protected in acting or refraining from acting upon any
resolution, certificate, statement, instrument, opinion, report, notice, request, direction, consent, order, bond, debenture, note, other evidence of indebtedness 

  

 31 

 
or other paper or document believed by it to be genuine and to have been signed or presented by the proper party or parties; 
  
 (b) any request or direction of the Company mentioned herein
shall be sufficiently evidenced by a Company Request or Company Order and any resolution of the Board of Directors of the Company may be sufficiently evidenced by a Board Resolution; 
  
 (c) whenever in the administration of this Indenture the Trustee shall deem it desirable that a matter be
proved or established prior to taking, suffering or omitting any action hereunder, the Trustee (unless other evidence be herein specifically prescribed) may, in the absence of bad faith on its part, request and rely upon an Officers’
Certificate; 
  
 (d) the Trustee may consult with
counsel of its selection and the advice of such counsel or any Opinion of Counsel shall be full and complete authorization and protection in respect of any action taken, suffered or omitted by it hereunder in good faith and in reliance thereon;

  
 (e) the Trustee shall be under no obligation
to exercise any of the rights or powers vested in it by this Indenture at the request or direction of any of the Holders pursuant to this Indenture, unless such Holders shall have offered to the Trustee security or indemnity reasonably satisfactory
to it against the costs, expenses and liabilities which might be incurred by it in compliance with such request or direction; 
  
 (f) the Trustee shall not be bound to make any investigation into the facts or matters stated in any resolution, certificate, statement,
instrument, opinion, report, notice, request, direction, consent, order, bond, debenture, note, other evidence of indebtedness or other paper or document, but the Trustee, in its discretion, may make such further inquiry or investigation into such
facts or matters as it may see fit; and, if the Trustee shall determine to make such further inquiry or investigation, it shall be entitled to examine the books, records and premises of the Company, personally or by agent or attorney at the sole
cost of the Company and shall incur no liability or additional liability of any kind by reason of such inquiry or investigation; 
  
 (g) the Trustee may execute any of the trusts or powers hereunder or perform any duties hereunder either directly or by or through agents
or attorneys and the Trustee shall not be responsible for any misconduct or negligence on the part of any agent or attorney appointed with due care by it hereunder; 
  
 (h) the Trustee shall not be charged with knowledge of any Default or Event of Default with respect to the
Securities unless either (i) a Responsible Officer shall have actual knowledge of such Default or Event of Default or (ii) written notice of such Default or Event of Default shall have been received by the Trustee from the Company or any other
obligor on such Securities or by any Holder of such Securities; 
  

 32 

 (i) the Trustee shall not be liable for any action taken, suffered or omitted by it in
good faith and reasonably believed by it to be authorized or within the discretion or rights or powers conferred upon it by this Indenture; 
  
 (j) the rights, privileges, protections, immunities and benefits given to the Trustee, including, without limitation, its right to be
indemnified, are extended to, and shall be enforceable by, the Trustee in each of its capacities hereunder, and each agent, custodian, director, officer, employee and other Person employed to act hereunder; 
  
 (k) the Trustee may request that the Company deliver an
Officers’ Certificate setting forth the names of individuals and/or titles of officers authorized at such time to take specified actions pursuant to this Indenture, which Officers’ Certificate may be signed by any person authorized to sign
an Officers’ Certificate, including any person specified as so authorized in any such certificate previously delivered and not superseded; and 
  
 (l) the permissive rights of the Trustee to take certain actions under this Indenture shall not be construed as a duty unless so specified
herein. 
  
 Section 6.04. Not Responsible for Recitals. The
recitals contained herein and in the Securities, except the Trustee’s certificates of authentication, shall be taken as the statements of the Company, and the Trustee assumes no responsibility for their correctness. The Trustee makes no
representations as to the validity, sufficiency or priority of this Indenture or of the Securities. The Trustee shall not be accountable for the use or application by the Company of Securities or the proceeds thereof. 
  
 Section 6.05. May Hold Securities. The Trustee, any Paying Agent, any
Security Registrar or any other agent of the Company, in its individual or any other capacity, may become the owner or pledgee of Securities and, subject to Section 6.08 and 6.13, may otherwise deal with the Company with the same rights it would
have if it were not Trustee, Paying Agent, Security Registrar or such other agent. 
  
 Section 6.06. Money Held in Trust. Money held by the Trustee in trust hereunder need not be segregated from other funds except to the extent required by law. The Trustee shall be under no liability for interest
on any money received by it hereunder except as otherwise agreed in writing with the Company. 
  
 Section 6.07. Compensation and Reimbursement. The Company agrees: 
  
 (i) to pay to the Trustee from time to time such compensation for all services rendered by it hereunder as the Company and the Trustee
shall from time to time agree in writing (which compensation shall not be limited by any provision of law in regard to the compensation of a trustee of an express trust); 
  
 (ii) except as otherwise expressly provided herein, to reimburse the Trustee upon its request for all
reasonable expenses, disbursements and advances 

  

 33 

 
incurred or made by the Trustee in accordance with any provision of this Indenture (including the reasonable compensation and the expenses and disbursements
of its agents and counsel), except any such expense, disbursement or advance as may be attributable to its negligence or willful misconduct; and 
  
 (iii) to indemnify the Trustee and any predecessor Trustee for, and to hold it harmless against, any loss, liability or expense including
taxes (other than taxes based upon, measured by or determined by the income of the Trustee) incurred without negligence or willful misconduct on its part, arising out of or in connection with the acceptance or administration of this trust, including
the reasonable costs and expenses of defending itself against any claim (whether assessed by the Company, by any Holder or any other Person) or liability in connection with the exercise or performance of any of its powers or duties hereunder.

  
 The obligations of the Company under this Section 6.07 shall
survive the resignation or removal of the Trustee and the satisfaction and discharge of this Indenture. To secure the Company’s payment obligations in this Section 6.07, the Trustee shall have a lien prior to the Securities on all money or
property held or collected by the Trustee, except for the Pledged Securities and the money or property held in trust to pay principal, interest and Liquidated Damages, if any, on the Securities. Such lien shall survive the resignation or removal of
the Trustee and the satisfaction and discharge of this Indenture. When the Trustee incurs expenses or renders services after a Default or an Event of Default specified in clauses (g) or (h) of Section 5.01 occurs, the expenses and the compensation
for the services (including the fees and expenses of its agents and counsel) are intended to constitute expenses of administration under Title 11 of the U.S. Code or any other similar foreign, federal or state law for the relief of debtors.

  
 Section 6.08. Disqualification; Conflicting Interests.
If the Trustee has or shall acquire a conflicting interest within the meaning of the Trust Indenture Act, the Trustee shall either eliminate such interest or resign, to the extent and in the manner provided by, and subject to the provisions of, the
Trust Indenture Act and this Indenture. 
  
 Section 6.09.
Corporate Trustee Required; Eligibility. There shall at all times be a Trustee hereunder which shall be a Person that is eligible pursuant to the Trust Indenture Act to act as such and has, or whose parent banking company has, a combined
capital and surplus of at least $50,000,000. If such Person publishes reports of condition at least annually, pursuant to law or to the requirements of said supervising or examining authority, then for the purposes of this Section 6.09, the combined
capital and surplus of such Person shall be deemed to be its combined capital and surplus as set forth in its most recent report of condition so published. If at any time the Trustee shall cease to be eligible in accordance with the provisions of
this Section 6.09, it shall resign immediately in the manner and with the effect hereinafter specified in this Article. 
  

 34 

 Section 6.10. Resignation and Removal; Appointment of Successor. (a) No resignation or removal of
the Trustee and no appointment of a successor Trustee pursuant to this Article 6 shall become effective until the acceptance of appointment by the successor Trustee under Section 6.11. 
  
 (b) The Trustee may resign at any time by giving written notice thereof to the Company. If an instrument of
acceptance by a successor Trustee shall not have been delivered to the Trustee within 30 days after the giving of such notice of resignation, the resigning Trustee may petition any court of competent jurisdiction at the expense of the Trustee for
the appointment of a successor Trustee. 
  
 (c)
The Trustee may be removed at any time by Act of the Holders of majority in Principal Amount of the Outstanding Securities, delivered to the Trustee and to the Company. If an instrument of acceptance by a successor Trustee shall not have been
delivered to the Trustee within 30 days after the notice of removal, the Trustee being removed may petition, at the expense of the Company, any court of competent jurisdiction for the appointment of a successor Trustee with respect to the
Securities. 
  
 (d) If at any time: 

 
 (i) the Trustee shall fail to comply with Section 6.08
after written request therefor by the Company or by any Holder who has been a bona fide Holder of a Security for at least six months, or 
  
 (ii) the Trustee shall cease to be eligible under Section 6.09 and shall fail to resign after written request therefor by the Company or
by any such Holder, or 
  
 (iii) the Trustee
shall become incapable of acting or shall be adjudged a bankrupt or insolvent, or 
  
 (iv) a receiver of the Trustee or of its property shall be appointed or any public officer shall take charge or control of the Trustee or
of its property or affairs for the purpose of rehabilitation, conservation or liquidation, 
  
 then, in any such case, (A) the Company by a Company Order may remove the Trustee, or (B) subject to Section 5.13, any Holder who has been a bona fide Holder of a Security for at least six months may, on behalf of
such Holder and all others similarly situated, petition any court of competent jurisdiction for the removal of the Trustee and the appointment of a successor Trustee. 
  
 (e) If the Trustee shall resign, be removed or become incapable of acting, or if a vacancy shall occur in
the office of Trustee for any cause, the Company, by a Company Order, shall promptly appoint a successor Trustee. If, within one year after such resignation, removal or incapability, or the occurrence of such vacancy, a successor Trustee shall be
appointed by Act of the Holders of a majority in Principal Amount of the Outstanding 

  

 35 

 
Securities delivered to the Company and the retiring Trustee, the successor Trustee so appointed shall, forthwith upon its acceptance of such appointment,
become the successor Trustee and supersede the successor Trustee appointed by the Company. If no successor Trustee shall have been so appointed by the Company or the Holders and accepted appointment in the manner hereinafter provided, any Holder who
has been a bona fide Holder of a Security for at least six months may, on behalf of himself and all others similarly situated, petition any court of competent jurisdiction for the appointment of a successor Trustee. 
  
 (f) The Company shall give notice of each resignation and
each removal of the Trustee and each appointment of a successor Trustee to all Holders in the manner provided in Section 1.06. Each notice shall include the name of the successor Trustee and the address of its Corporate Trust Office. 
  
 Section 6.11. Acceptance of Appointment by Successor. Every successor
Trustee appointed hereunder shall execute, acknowledge and deliver to the Company and to the retiring Trustee an instrument accepting such appointment, and thereupon the resignation or removal of the retiring Trustee shall become effective and such
successor Trustee, without any further act, deed or conveyance, shall become vested with all the rights, powers, trusts and duties of the retiring Trustee; but, on request of the Company or the successor Trustee, such retiring Trustee shall, upon
payment of its charges, execute and deliver an instrument transferring to such successor Trustee all the rights, powers and trusts of the retiring Trustee and shall duly assign, transfer and deliver to such successor Trustee all property and money
held by such retiring Trustee hereunder. Upon request of any such successor Trustee, the Company shall execute any and all instruments for more fully and certainly vesting in and confirming to such successor Trustee all such rights, powers and
trusts. 
  
 No successor Trustee shall accept its appointment
unless at the time of such acceptance such successor Trustee shall be qualified and eligible under this Article 6. 
  
 Notwithstanding the resignation or removal of the Trustee, the Company’s obligations under Section 6.07 shall continue for the benefit of the
retiring trustee with respect to expenses and liabilities incurred by it prior to such resignation or removal. 
  
 Section 6.12. Merger, Conversion, Consolidation or Succession to Business. Any corporation into which the Trustee may be merged or converted or
with which it may be consolidated, or any corporation resulting from any merger, conversion or consolidation to which the Trustee shall be a party, or any corporation succeeding to all or substantially all the corporate trust business of the Trustee
by sale or otherwise, shall be the successor of the Trustee hereunder, provided such corporation shall be otherwise qualified and eligible under this Article 6, without the execution or filing of any paper or any further act on the part of any of
the parties hereto. In case any Securities shall have been authenticated, but not delivered, by the Trustee then in office, any successor by merger, conversion or consolidation to such authenticating Trustee may adopt such 

  

 36 

 
authentication and deliver the Securities so authenticated with the same effect as if such successor Trustee had itself authenticated such Securities.

  
 Section 6.13. Preferential Collection of Claims
Against. If and when the Trustee shall be or become a creditor of the Company (or any other obligor upon the Securities), the Trustee shall be subject to the provisions of the Trust Indenture Act regarding the collection of claims against the
Company (or any such other obligor). 
  
 ARTICLE 7 
 Holders’ Lists And Reports By Trustee 
  
 Section 7.01. Company to Furnish Trustee Names and Addresses of Holders. The Company will furnish or cause to be furnished to the Trustee:

  
 (i) semi-annually, not more than 15 days
after each Record Date, a list, in such form as the Trustee may reasonably require, of the names and addresses of the Holders as of such Record Date; and 
  
 (ii) at such other times as the Trustee may request in writing, within 30 days after the receipt by the Company of any such request, a
list of similar form and content as of a date not more than 15 days prior to the time such list is furnished; 
  
 excluding from any such list names and addresses received by the Trustee in its capacity as Security Registrar; provided, however, that no such list need be furnished so long as the Trustee is acting as Security
Registrar. 
  
 Section 7.02. Preservation of Information;
Communications to Holders. (a) The Trustee shall preserve, in as current a form as is reasonably practicable, the names and addresses of Holders contained in the most recent list furnished to the Trustee as provided in Section 7.01 and the names
and addresses of Holders received by the Trustee in its capacity as Security Registrar. The Trustee may destroy any list furnished to it as provided in Section 7.01 upon receipt of a new list so furnished. 
  
 (b) The rights of Holders to communicate with other Holders
with respect to their rights under this Indenture or under the Securities, and the corresponding rights and duties of the Trustee, shall be as provided by the Trust Indenture Act. 
  
 (c) Every Holder of Securities, by receiving and holding the same, agrees with the Company and the Trustee
that neither the Company nor the Trustee nor any agent of either of them shall be held accountable by reason of any disclosure of information as to names and addresses of Holders made pursuant to the Trust Indenture Act. 
  
 Section 7.03. Reports By Trustee. (a) The Trustee shall transmit to
Holders such reports concerning the Trustee and its actions under this Indenture as may be 

  

 37 

 
required pursuant to the Trust Indenture Act at the times and in the manner provided pursuant thereto. Reports so required to be transmitted at stated
intervals of not more than 12 months shall be transmitted no later than July 15 in each calendar year, commencing in July 15, 2004. Each such report shall be dated as of a date not more than 60 days prior to the date of transmission. 
  
 (b) A copy of each such report shall, at the time of such
transmission to Holders, be filed by the Trustee with each stock exchange, if any, upon which the Securities are listed, with the Commission and with the Company. The Company will notify the Trustee when the Securities are listed on any stock
exchange or of any delisting thereof. 
  
 Section 7.04. Reports
by Company. The Company shall file with the Trustee and the Commission, and transmit to Holders, such information, documents and other reports, and such summaries thereof, as may be required pursuant to the Trust Indenture Act at the times and
in the manner provided pursuant to such Act; provided that any such information, documents or reports required to be filed with the Commission pursuant to Section 13 or 15(d) of the Exchange Act shall be filed with the Trustee within 15 days after
the same is so required to be filed with the Commission. In the event the Company is not subject to Section 13 or 15(d) of the Exchange Act, it shall file with the Trustee upon request the information required to be delivered pursuant to Rule
144A(d)(4) under the Securities Act. It is expressly understood that materials transmitted electronically by the Company to the Trustee shall be deemed filed with the Trustee for purposes of this Section 7.04. The Trustee shall not be under a duty
to review or evaluate any report or information delivered to the Trustee pursuant to the provisions of this Section 7.04 for the purposes of making such reports available to it and to the Holders of Securities who may request such information.
Delivery of such reports, information and documents to the Trustee as may be required under this Section 7.04 is for informational purposes only and the Trustee’s receipt of such shall not constitute constructive notice of any information
contained therein or determinable from information contained therein, including the Company’s compliance with any of its covenants hereunder (as to which the Trustee is entitled to rely exclusively on an Officers’ Certificate). 

 
 ARTICLE 8 
 Consolidation, Merger, Conveyance, Transfer Or Lease 
  
 Section 8.01. Company May Consolidate, etc., Only on Certain Terms. The Company shall not consolidate with or merge into any other Person or
convey, transfer or lease its properties and assets substantially as an entirety to any Person, and the Company shall not permit any Person to consolidate with or merge into the Company or convey, transfer or lease its properties and assets
substantially as an entirety to the Company, unless: 
  
 (a) either (i) the Company shall be the continuing Person or (ii) the Person (if other than the Company) formed by such consolidation or into which the Company is merged or the Person which acquires by conveyance or transfer, or which
leases, the properties 
  

 38 

 
and assets of the Company substantially as an entirety (the “Surviving Entity”), (1) shall be either (a) organized and validly existing
under the laws of the United States of America, any State thereof or the District of Columbia, or (b) organized under the laws of a jurisdiction outside the United States and has common stock traded on a national securities exchange in the United
States and a worldwide total market capitalization of its equity securities before giving effect to the consolidation or merger of at least US$2 billion, and (2) the Surviving Entity shall expressly assume, by an indenture supplemental hereto,
executed and delivered to the Trustee, all of the obligations of the Company under the Securities and this Indenture; 
  
 (b) immediately after giving effect to such transaction, no Event of Default, and no event which, after notice or lapse of time or both,
would become an Event of Default, shall have occurred and be continuing; and 
  
 (c) the Company or the Surviving Entity has delivered to the Trustee an Officers’ Certificate and an Opinion of Counsel, each stating that such consolidation, merger, conveyance, transfer or lease and, if a
supplemental indenture is required in connection with such transaction, such supplemental indenture comply with this Article 8 and Article 9, respectively. 
  
 Section 8.02. Successor Substituted. Upon any consolidation of the Company with, or merger of the Company into, any other Person or any conveyance,
transfer or lease of the properties and assets of the Company substantially as an entirety in accordance with Section 8.01, the successor Person formed by such consolidation or into which the Company is merged or to which such conveyance, transfer
or lease is made shall succeed to, and be substituted for, and may exercise every right and power of, the Company under this Indenture with the same effect as if such successor Person had been named as the Company herein, and thereafter, except in
the case of a lease, the predecessor Person shall be relieved of all obligations and covenants under this Indenture and the Securities. 
  
 ARTICLE 9 
 Supplemental Indentures 

 
 Section 9.01. Supplemental Indentures Without Consent of Holders.
Without the consent of any Holders, the Company, when authorized by a Board Resolution, and the Trustee, at any time and from time to time, may enter into one or more indentures supplemental hereto, in form satisfactory to the Trustee, for any of
the following purposes: 
  
 (i) to evidence the
succession of another Person to the Company and the assumption by any such successor of the covenants of the Company herein and in the Securities; or 
  
 (ii) to add to the covenants of the Company for the benefit of the Holders, or to surrender any right or power herein conferred upon the
Company; or 
  

 39 

 (iii) to provide for a successor Trustee with respect to the Securities; or 

 
 (iv) to cure any ambiguity or defect, to correct or
supplement any provision herein which may be inconsistent with any other provision herein, or to make any other provisions with respect to matters or questions arising under this Indenture which shall not be inconsistent with the provisions of this
Indenture; provided that such action pursuant to this clause (iv) shall not adversely affect the interests of the Holders in any material respect; or 
  
 (v) to add any additional Events of Default for the benefit of the Holders; or 
  
 (vi) to convey, transfer, assign, mortgage or pledge to the
Trustee as security for the Securities any property or assets; or 
  
 (vii) to increase the Conversion Rate of the Securities; provided, however, that such increase shall be in accordance with the terms of this Indenture or shall not adversely affect the interests of the Holders of the
Securities; or 
  
 (viii) to supplement any
provision of this Indenture to such extent as shall be necessary to permit or facilitate the discharge of the Securities; provided that such change or modification does not adversely affect the interests of the Holders of the Securities; or

  
 (ix) to make any change or modification
necessary in connection with the registration of the Securities under the Securities Act as contemplated in the Registration Rights Agreement; provided that such change or modification does not adversely affect the interests of the Holders of
Securities; or 
  
 (x) to add or modify any other
provision herein with respect to matters or questions arising hereunder which the Company and the Trustee may deem necessary or desirable and which would not reasonably be expected to adversely affect the interests of the Holders of Securities in
any material respect. 
  
 Section 9.02. Supplemental Indentures
With Consent of Holders. With the consent of the Holders of not less than a majority in Principal Amount of the Outstanding Securities, by Act of said Holders delivered to the Company and the Trustee, the Company, when authorized by a Board
Resolution, and the Trustee may enter into an indenture or indentures supplemental hereto for the purpose of adding any provisions to or changing in any manner or eliminating any of the provisions of this Indenture or of modifying in any manner the
rights of the Holders under this Indenture; provided, however, that no such supplemental indenture shall, without the consent of the Holder of each Outstanding Security affected thereby, 
  
 (i) reduce the rate of or extend the time for payment of interest, if any, on the Security; or 

 

 40 

 (ii) reduce the Principal Amount of, or extend the Stated Maturity of, any Security; or

  
 (iii) make any change that impairs or
adversely affects the conversion rights of any Securities; or 
  
 (iv) reduce the Redemption Price, the Repurchase Price or Fundamental Change Repurchase Price of any Security or amend or modify in any manner adverse to the Holders of Securities the Company’s obligation to make
such payments, whether through an amendment or waiver of provisions in the covenants, definitions or otherwise; or 
  
 (v) modify the provisions with respect to the right of Holders to cause the Company to repurchase Securities upon a Fundamental Change in
a manner adverse to Holders of Securities; or 
  
 (vi) make any interest or principal on a Security payable in money other than that stated in the Security or other than in accordance with the provisions of this Indenture; or 
  
 (vii) impair the right of any Holder to receive payment of the Principal Amount of or interest or Liquidated
Damages, if any, on a Holder’s Securities on or after the due dates therefor or to institute suit for the enforcement of any payment on or with respect to such Holder’s Securities; or 
  
 (viii) reduce the quorum or voting requirements under this
Indenture; or 
  
 (ix) change the ranking of the
Securities in a manner adverse to the Holders of the Securities; or 
  
 (x) make any change in the amendment provisions which require each Holder’s consent or in the waiver provisions; or 
  
 (xi) reduce the percentage in Principal Amount of the Outstanding Securities, the consent of whose Holders is required for any such
supplemental indenture, or the consent of whose Holders is required for any waiver (of compliance with certain provisions of this Indenture or certain defaults hereunder and their consequences) provided for in this Indenture; or 
  
 (xii) modify any of the provisions of this Section 9.02 or
Section 5.12, except to increase any such percentage or to provide that certain other provisions 

  

 41 

 
of this Indenture cannot be modified or waived without the consent of the Holder of each Outstanding Security affected thereby; or 
  
 (xiii) modify the provisions of the Indenture or the Pledge
Agreement relating to the Pledged Securities in a manner adverse to the Holders in any material respect. 
  
 It shall not be necessary for any Act of Holders under this Section 9.02 to approve the particular form of any proposed supplemental indenture, but it
shall be sufficient if such Act shall approve the substance thereof. 
  
 Section 9.03. Execution of Supplemental Indentures. In executing, or accepting the additional trusts created by, any supplemental indenture permitted by this Article 9 or the modifications thereby of the trusts created by this
Indenture, the Trustee shall be provided with, and (subject to Section 6.01) shall be fully protected in relying upon, in addition to the documents required by Section 1.02, an Opinion of Counsel stating that the execution of such supplemental
indenture is authorized or permitted by this Indenture. Subject to the preceding sentence, the Trustee shall sign such supplemental indenture if the same does not adversely affect the Trustee’s own rights, duties or immunities under this
Indenture or otherwise. The Trustee may, but shall not be obligated to, enter into any such supplemental indenture that adversely affects the Trustee’s own rights, duties or immunities under this Indenture or otherwise. 
  
 Section 9.04. Effect of Supplemental Indentures. Upon the execution of
any supplemental indenture under this Article 9, this Indenture shall be modified in accordance therewith, and such supplemental indenture shall form a part of this Indenture for all purposes; and every Holder of Securities theretofore or thereafter
authenticated and delivered hereunder shall be bound thereby. 
  
 Section 9.05. Conformity with Trust Indenture Act. Every supplemental indenture executed pursuant to this Article shall conform to the requirements of the Trust Indenture Act. 
  
 Section 9.06. Reference in Securities to Supplemental Indentures.
Securities authenticated and delivered after the execution of any supplemental indenture pursuant to this Article 9 shall bear a notation in form approved by the Trustee as to any matter provided for in such supplemental indenture. If the Company
shall so determine, new Securities so modified as to conform, in the opinion of the Trustee and the Company, to any such supplemental indenture may be prepared and executed by the Company and authenticated and delivered by the Trustee in exchange
for Outstanding Securities. 
  

 42 

 ARTICLE 10 
 Covenants 
  
 Section 10.01.
Payments. The Company shall duly and punctually make all payments in respect of the Securities in accordance with the terms of the Securities and this Indenture. 
  
 Any payments made or due pursuant to this Indenture shall be considered paid on the applicable date due if by 10:00 a.m.,
New York City time, on such date the Paying Agent holds, in accordance with this Indenture, cash sufficient to pay all such amounts then due. Payment of the principal, interest and Liquidated Damages, if any, on the Securities shall be in such coin
or currency of the United States of America as at the time of payment is legal tender for payment of public and private debts. 
  
 Section 10.02. Maintenance of Office or Agency. The Company shall maintain in the Borough of Manhattan, The City of New York, an office or agency
where Securities may be presented or surrendered for payment, where Securities may be surrendered for registration of transfer or exchange and where notices and demands to or upon the Company in respect of the Securities and this Indenture may be
served, which shall initially be the Corporate Trust Office of the Trustee. The Company shall give prompt written notice to the Trustee of any change in the location, of such office or agency. If at any time the Company shall fail to maintain any
such required office or agency or shall fail to furnish the Trustee with the address thereof, such presentations, surrenders, notices and demands may be made or served at the Corporate Trust Office of the Trustee, and the Company hereby appoints the
Trustee as its agent to receive all such presentations, surrenders, notices and demands. 
  
 The Company may also from time to time designate one or more other offices or agencies (in or outside the Borough of Manhattan, The City of New York) where the Securities may be presented or surrendered for any or all
such purposes and may from time to time rescind such designations; provided, however, that no such designation or rescission shall in any manner relieve the Company of its obligation to maintain an office or agency in the Borough of Manhattan, The
City of New York, for such purposes. The Company shall give prompt written notice to the Trustee of any such designation or rescission and of any change in the location of any such other office or agency. The Company hereby initially designates U.S.
Bank National Association, U.S. Bank Trust New York, 100 Wall Street, Suite 1600, New York, NY 10005 as one such office or agency of the Company. 
  
 Section 10.03. Money for Security Payments to be Held in Trust. If the Company shall at any time act as its own Paying Agent, it shall, on or
before each due date of any payment in respect of any of the Securities, segregate and hold in trust for the benefit of the Persons entitled thereto a sum sufficient to make the payment so becoming due until such sums shall be paid to such Persons
or otherwise disposed of as herein provided and shall promptly notify the Trustee of its action or failure so to act. 
  

 43 

 Whenever the Company shall have one or more Paying Agents, it will, prior to each due date of any payment
in respect of any Securities, deposit with a Paying Agent a sum sufficient to pay such amount, such sum to be held as provided by the Trust Indenture Act, and (unless such Paying Agent is the Trustee) the Company will promptly notify the Trustee of
its action or failure so to act. 
  
 The Company shall cause each
Paying Agent other than the Trustee to execute and deliver to the Trustee an instrument in which such Paying Agent shall agree with the Trustee, subject to the provisions of this Section 10.03, that such Paying Agent will (i) comply with the
provisions of the Trust Indenture Act applicable to it as a Paying Agent and (ii) during the continuance of any default by the Company (or any other obligor upon the Securities) in the making of any payment in respect of the Securities, upon the
written request of the Trustee, forthwith pay to the Trustee all sums held in trust by such Paying Agent as such. 
  
 The Company may at any time, for the purpose of obtaining the satisfaction and discharge of this Indenture or for any other purpose, pay, or by Company
Order direct any Paying Agent to pay, to the Trustee all sums held in trust by the Company or such Paying Agent, such sums to be held by the Trustee upon the same trusts as those upon which such sums were held by the Company or such Paying Agent;
and, upon such payment by any Paying Agent to the Trustee, such Paying Agent shall be released from all further liability with respect to such money. 
  
 Any money deposited with the Trustee or any Paying Agent, or then held by the Company, in trust for the making of payments in respect of any Security and
remaining unclaimed for two years after such payment has become due shall be paid to the Company on Company Request, or (if then held by the Company) shall be discharged from such trust; and the Holder of such Security shall thereafter, as an
unsecured general creditor, look only to the Company for payment thereof, and all liability of the Trustee or such Paying Agent with respect to such trust money, and all liability of the Company as trustee thereof, shall thereupon cease; provided,
however, that the Trustee or such Paying Agent, before being required to make any such repayment, may at the expense of the Company cause to be published once, in a newspaper published in the English language, customarily published on each Business
Day and of general circulation in The City of New York, notice that such money remains unclaimed and that, after a date specified therein, which shall not be less than 30 days from the date of such publication, any unclaimed balance of such money
then remaining shall be repaid to the Company. In the absence of a written request from the Company to return funds remaining unclaimed for two years after such payment has become due to the Company, the Trustee shall from time to time deliver all
unclaimed payments to or as directed by applicable escheat authorities, as determined by the Trustee in its sole discretion, in accordance with the customary practices and procedures of the Trustee. Any such unclaimed funds held by the Trustee
pursuant to this Section 10.03 shall be held uninvested and without any liability for interest. 
  
 Section 10.04. Statement by Officers as to Default. The Company will deliver to the Trustee, within 120 days after the end of each fiscal year of
the Company 

  

 44 

 
ending after the date hereof, an Officers’ Certificate, stating whether or not to the knowledge of the signers thereof the Company is in Default in the
performance and observance of any of the terms, provisions and conditions of this Indenture (without regard to any period of grace or requirement of notice provided hereunder) and, if the Company shall be in Default, specifying all such Defaults and
the nature and status thereof of which they may have knowledge. 
  
 The Company shall deliver to the Trustee, as soon as possible and in any event within 30 days after the Company becomes aware of the occurrence of any Event of Default or an event which, with notice or the lapse of time or both, would
constitute an Event of Default, an Officers’ Certificate setting forth the details of such Event of Default or default and the action which the Company is taking or proposes to take with respect thereto. 
  
 Section 10.05. Existence. Subject to Article 8, the Company shall do
or cause to be done all things necessary to preserve and keep in full force and effect its existence, rights (charter and statutory) and franchises; provided, however, that the Company shall not be required to preserve any such right or franchise if
the Board of Directors of the Company shall determine that the preservation thereof is no longer desirable in the conduct of the business of the Company and that the loss thereof is not disadvantageous in any material respect to the Holders.

  
 Section 10.06. Reports and Delivery of Certain
Information. Whether or not required by the rules and regulations of the Commission, so long as any Securities are outstanding, the Company shall promptly furnish to the Trustee (i) all quarterly and annual financial information that is
substantially equivalent to that which would be required to be contained in a filing with the Commission on Forms 10-Q and 10-K if the Company were required to file such Forms, including a “Management’s Discussion and Analysis of Financial
Condition and Results of Operations” section and, with respect to the annual information only, a report thereon by the Company’s certified independent accountants and (ii) all reports that are substantially equivalent to that which would
be required to be filed with the Commission on Form 8-K if the Company were required to file such reports; provided that in each case the delivery of materials to the Trustee by electronic means shall be deemed to be “furnished” to the
Trustee for purposes of this Section 10.06. In addition, whether or not required by the rules and regulations of the Commission, the Company shall file a copy of all such information with the Commission for public availability (unless the Commission
will not accept such a filing) and make such information available to investors who request it in writing. So long as any of the Securities remain Outstanding, the Company shall make available to any prospective purchaser of Securities or beneficial
owner of Securities in connection with any sale thereof the information required by Rule 144A(d)(4) under the Securities Act, until the earlier of (a) such time as the Holders thereof have disposed of such Securities pursuant to an effective Resale
Registration Statement or Rule 144 under the Securities Act and (b) the date that is two years from the Issue Date. 
  

 45 

 Section 10.07. Resale of Certain Securities. During the period beginning on the Issue Date and
ending on the date that is two years from the Issue Date, the Company shall not, and shall not permit any of its “affiliates” (as defined under Rule 144 under the Securities Act or any successor provision thereto) to, resell any
Securities which constitute “restricted securities” under Rule 144 that have been reacquired by any of them. The Trustee shall have no responsibility in respect of the Company’s performance of its agreement in the preceding
sentence. 
  
 Section 10.08. Book-Entry System. If the
Securities cease to trade in the Depositary’s book-entry settlement system, the Company covenants and agrees that it shall use reasonable efforts to make such other book entry arrangements that it determines are reasonable for the Securities.

  
 Section 10.09. Liquidated Damages Under the Registration
Rights Agreement. If at any time Liquidated Damages become payable by the Company pursuant to the Registration Rights Agreement, the Company shall promptly deliver to the Trustee a certificate to that effect and stating (i) the amount of such
Liquidated Damages that are payable and (ii) the date on which such Liquidated Damages are payable pursuant to the terms of the Registration Rights Agreement. Unless and until a Responsible Officer of the Trustee receives such a certificate, the
Trustee may assume without inquiry that no Liquidated Damages are payable. If the Company has paid Liquidated Damages directly to the Persons entitled to such Liquidated Damages, the Company shall deliver to the Trustee a certificate setting forth
the particulars of such payment. 
  
 Section 10.10. Information
for IRS Filings. The Company shall provide to the Trustee on a timely basis such information as the Trustee requires to enable the Trustee to prepare and file any form required to be submitted by the Company with the Internal Revenue Service and
the Holders of the Securities. 
  
 ARTICLE 11 
 Redemption And Repurchase Upon A Fundamental Change 
  
 Section 11.01. Right to Redeem; Notices to Trustee. Prior to May 10, 2010, the Securities are not redeemable. At any time commencing on May 10,
2010, the Securities are redeemable as a whole, or from time to time in part, at the option of the Company at the Redemption Price equal to 100% expressed as a percentage of the Principal Amount of Securities to be redeemed, together with accrued
and unpaid interest and Liquidated Damages, if any, to, but excluding, the Redemption Date. 
  
 The Company shall give the notice to the Trustee provided for in this Section 11.01 by a Company Order, at least 30 days but not more than 60 days before the Redemption Date (unless a shorter notice shall be
satisfactory to the Trustee). 
  

 46 

 Section 11.02. Selection of Securities to be Redeemed. If less than all the Securities are to be
redeemed, the Trustee shall select the Securities to be redeemed pro rata or by lot or by any other method the Trustee considers fair and appropriate (so long as such method is not prohibited by the rules of any stock exchange on which the
Securities are then listed). The Trustee shall make the selection within seven days from its receipt of the notice from the Company delivered pursuant to the second paragraph of Section 11.01 from Outstanding Securities not previously called for
redemption. 
  
 Securities and portions of them the Trustee
selects shall be in Principal Amounts of $1,000 or integral multiples of $1,000. Provisions of this Indenture that apply to Securities called for redemption in whole also apply to Securities called for redemption in part. The Trustee shall notify
the Company promptly of the Securities or portions of Securities to be redeemed. 
  
 If any Security selected for partial redemption is converted in part before termination of the conversion right with respect to the portion of the Security so selected, the converted portion of such Security shall be
deemed (so far as may be) to be the portion selected for redemption. Securities which have been converted during a selection of Securities to be redeemed may be treated by the Trustee as outstanding for the purpose of such selection. 
  
 Section 11.03. Notice of Redemption. At least 30 days but not more
than 60 days before a Redemption Date, the Company shall mail a notice of redemption by first-class mail, postage prepaid, to each Holder of Securities to be redeemed. 
  
 The notice shall identify the Securities to be redeemed and shall state: 
  
 (i) the Redemption Date; 
  
 (ii) the Redemption Price; 
  
 (iii) the Conversion Price; 
  
 (iv) the name and address of the Paying Agent and Conversion
Agent; 
  
 (v) that Securities called for
redemption may be converted at any time before the close of business on the Business Day immediately preceding the Redemption Date; 
  
 (vi) that Holders who want to convert Securities must satisfy the requirements set forth therein and in this Indenture; 
  
 (vii) that Securities called for redemption must be
surrendered to the Paying Agent for cancellation to collect the Redemption Price; 
  

 47 

 (viii) if fewer than all the outstanding Securities are to be redeemed, the certificate
number (if such Securities are held other than in global form) and Principal Amounts of the particular Securities to be redeemed; 
  
 (ix) that, unless the Company defaults in making payment of such Redemption Price, interest and Liquidated Damages, if any, will cease to
accrue on and after the Redemption Date with respect to the Securities to be redeemed; and 
  
 (x) the CUSIP number of the Securities. 
  
 At the Company’s written request delivered at least 15 days prior to the date such notice is to be given (unless a shorter time period shall be
acceptable to the Trustee), the Trustee shall give the notice of redemption in the Company’s name and at the Company’s expense. 
  
 Section 11.04. Effect of Notice of Redemption. Once notice of redemption is given, Securities called for redemption become due and payable on the
Redemption Date and at the Redemption Price stated in the notice except for Securities which are converted in accordance with the terms of this Indenture. Upon surrender to the Paying Agent, such Securities shall be paid at the Redemption Price
stated in the notice. 
  
 Section 11.05. Deposit of Redemption
Price. Prior to 10:00 a.m. (New York City time) on a Redemption Date, the Company shall deposit with the Paying Agent (or if the Company or a Subsidiary or an Affiliate of either of them is the Paying Agent, shall segregate and hold in trust)
money sufficient to pay the Redemption Price of all Securities to be redeemed on that date other than Securities or portions of Securities called for redemption which on or prior thereto have been delivered by the Company to the Trustee for
cancellation or have been converted. The Paying Agent shall as promptly as practicable return to the Company any money not required for that purpose because of conversion of Securities pursuant to Article 13. If such money is then held by the
Company in trust and is not required for such purpose it shall be discharged from such trust. 
  
 Section 11.06. Securities Redeemed in Part. Upon surrender of a Security that is redeemed in part, the Company shall execute and the Trustee shall authenticate and deliver to the Holder a new Security in an
authorized denomination equal in principal amount to the unredeemed portion of the Security surrendered. The Company shall not be required to (i) issue, register the transfer of, or exchange any Securities during a period of 15 days before the
Redemption Date or (ii) register the transfer of, or exchange any, Securities so selected for redemption, in whole or in part, except the unredeemed portion of any Security being redeemed in part. 
  
 Section 11.07. Conversion Arrangement on Call for Redemption. In
connection with any redemption of Securities, the Company may arrange for the purchase 

  

 48 

 
and conversion of any Securities called for redemption by an agreement with one or more investment bankers or other purchasers to purchase such Securities by
paying to the Trustee in trust for the Securityholders, on or prior to 10:00 a.m. New York City time on the Redemption Date, an amount that, together with any amounts deposited with the Trustee by the Company for the redemption of such Securities,
is not less than the Redemption Price of such Securities. Notwithstanding anything to the contrary contained in this Article 11, the obligation of the Company to pay the Redemption Price of such Securities shall be deemed to be satisfied and
discharged to the extent such amount is so paid by such purchasers. If such an agreement is entered into, any Securities not duly surrendered for conversion by the Holders thereof may, at the option of the Company, be deemed, to the fullest extent
permitted by law, acquired by such purchasers from such Holders and (notwithstanding anything to the contrary contained in Article 13) surrendered by such purchasers for conversion, all as of immediately prior to the close of business on the
Business Day prior to the Redemption Date, subject to payment of the above amount as aforesaid. The Trustee shall hold and pay to the Holders whose Securities are selected for redemption any such amount paid to it for purchase and conversion in the
same manner as it would moneys deposited with it by the Company for the redemption of Securities. Without the Trustee’s prior written consent, no arrangement between the Company and such purchasers for the purchase and conversion of any
Securities shall increase or otherwise affect any of the powers, duties, responsibilities or obligations of the Trustee as set forth in this Indenture, and the Company agrees to indemnify the Trustee from, and hold it harmless against, any loss,
liability or expense arising out of or in connection with any such arrangement for the purchase and conversion of any Securities between the Company and such purchasers, including the costs and expenses incurred by the Trustee in the defense of any
claim or liability arising out of or in connection with the exercise or performance of any of its powers, duties, responsibilities or obligations under this Indenture, except in the case of the Trustee’s negligence or willful misconduct.

  
 Section 11.08. Repurchase of Securities at Option of the
Holder Upon Fundamental Change. 
  
 (a)
General. If prior to the Stated Maturity there shall have occurred a Fundamental Change, Securities shall be repurchased by the Company at the Fundamental Change Repurchase Price on a date specified by the Company that is not less than 25
days nor more than 35 days after the date of the mailing of a Fundamental Change Company Notice pursuant to clause (b) of this Section 11.08 (the “Fundamental Change Repurchase Date”), at the option of the Holder thereof, in
accordance with the following procedures; provided that the Company shall not be required to repurchase the Securities pursuant to this Section 11.08 if the Closing Price per share of Common Stock for any five Trading Days within the period of ten
consecutive Trading Days ending immediately after the later of the Fundamental Change and the public announcement of the Fundamental Change equals or exceeds 110% of the Conversion Price of the Securities in effect on each of those five Trading
Days. 
  

 49 

 (b) Make-Whole Premium. If prior to the Stated Maturity there shall have occurred
a Fundamental Change and all of the consideration for the Common Stock in the transaction or transactions constituting the Fundamental Change consists of cash (a “Cash Buy-Out”), the Company will pay a Make-Whole Premium to the
Holders of the Securities in addition to the Fundamental Change Repurchase Price. 
  
 The “Make-Whole Premium” per Security will equal (a) the average of the Trading Prices of a Security for the five Trading
Days immediately prior to the Company’s public announcement of the Cash Buy-Out, less (b) the greater of (i) $1,000 or (ii) the product of (x) the average Closing Prices of the Common Stock for the five Trading Days immediately prior to the
Company’s public announcement of the Cash Buy-Out and (y) the applicable Conversion Rate. The Make-Whole Premium, if any, will not be less than zero. 
  
 The Trustee shall have no duty to calculate the Make-Whole Premium. The Company shall make the calculations described in this Section
11.08, using the Trading Price provided by the Trustee. The Trustee shall be entitled in its sole discretion to consult with the Company and to request the assistance of the Company in connection with the Trustee’s duties pursuant to this
Section 11.08, and the Company agrees, if requested by the Trustee, to cooperate with, and provide assistance to, the Trustee in carrying out its duties under this Section 11.08. 
  
 The Make-Whole Premium may be paid for, at the election of the Company, in cash or shares of Common Stock,
provided that the shares of Common Stock will be issued out of the Company’s authorized but unissued Common Stock and will, upon issuance, be duly and validly issued and fully paid and nonassessable and free of any preemptive or similar rights.

  
 (c) Company Notice of Fundamental
Change. Within 15 days after the Company knows or reasonably should know of the occurrence of a Fundamental Change, the Company shall, if Holders have the right to require the Company to repurchase Securities hereunder, deliver a written notice
of Fundamental Change (the “Fundamental Change Company Notice”) by first-class mail or by overnight courier to the Trustee and to each Holder (and to beneficial owners as required by applicable law). The notice shall include a form
of Fundamental Change Repurchase Notice to be completed by the Securityholder and shall state: 
  
 (i) the events causing a Fundamental Change and the date of such Fundamental Change; 
  
 (ii) the date by which a Holder must deliver a Fundamental
Change Repurchase Notice to elect the repurchase option pursuant to this Section 11.08; 
  
 (iii) the Fundamental Change Repurchase Date; 
  
 (iv) the Fundamental Change Repurchase Price; 
  

 50 

 (v) whether the Fundamental Change Repurchase Price will be paid in cash, shares of
Common Stock or a combination thereof, specifying the percentages of each; 
  
 (vi) if shares of Common Stock will be used to pay all or part of the Fundamental Change Repurchase Price, state: 
  
 the method for valuing the shares of Common Stock to be delivered in connection with the repurchase; and 
  
 that Holders of the Securities will bear the market risk with
respect to the value of the shares of Common Stock to be delivered from the date the number of shares is determined; 
  
 (vii) the name and address of the Paying Agent and the Conversion Agent; 
  
 (viii) the Conversion Rate applicable on the date of the Fundamental Change Company Notice; 
  
 (ix) that Securities as to which a Fundamental Change
Repurchase Notice has been given may be converted pursuant to Article 13 hereof only if the Fundamental Change Repurchase Notice has been withdrawn in accordance with the terms of this Indenture; 
  
 (x) that Securities must be surrendered to the Paying Agent
for cancellation to collect payment; 
  
 (xi)
that the Fundamental Change Repurchase Price for any Security as to which a Fundamental Change Repurchase Notice has been duly given and not withdrawn will be paid promptly following the later of the Fundamental Change Repurchase Date and the time
of surrender of such Security as described in clause (x) above; 
  
 (xii) the procedures the Holder must follow to exercise rights under this Section 11.08; 
  
 (xiii) the conversion rights of the Securities; 
  

(xiv) the procedures for withdrawing a Fundamental Change Repurchase Notice; 
  
 (xv) that, unless the Company defaults in making payment of
such Fundamental Change Repurchase Price, Securities covered by any Fundamental Change Repurchase Notice will cease to be outstanding and interest and 

  

 51 

 
Liquidated Damages, if any, will cease to accrue on and after the Fundamental Change Repurchase Date; 
  
 (xvi) the CUSIP number of the Securities; and 
  
 (xvii) whether or a Make-Whole Premium is required to be
paid by the Company and whether such Make-Whole Premium shall be paid in cash or by delivery of shares of Common Stock. 
  
 At the Company’s request, the Trustee shall give such Fundamental Change Company Notice in the Company’s name and at the Company’s expense;
provided that, in all cases, the text of such Fundamental Change Company Notice shall be prepared by the Company. In connection with delivery of the Fundamental Change Company Notice to the Holders, the Company shall publish a notice containing
substantially the same information that is required in the Fundamental Change Company Notice in a newspaper published in the English language, customarily published each Business Day and of general circulation in The City of New York, or publish
such information on the Company’s website or through such other public medium as the Company may use at such time. 
  
 (d) Fundamental Change Repurchase Notice. In order to exercise its rights under Section 11.08 hereof, a Holder must deliver to the
Paying Agent: 
  
 a written notice of repurchase
(a “Fundamental Change Repurchase Notice”), substantially in the form of Exhibit D hereto, at any time from the opening of business on the date of the Fundamental Change Company Notice until the close of business on Business
Day prior to the Fundamental Change Repurchase Date stating: 
  
 the certificate number (if such Security is held other than in global form) of the Security which the Holder will deliver to be purchased; 
  
 the portion of the Principal Amount of the Security which the Holder will deliver to be purchased, which
portion must be in a Principal Amount of $1,000 or integral multiples thereof; and 
  
 that such Security shall be purchased as of the Fundamental Change Repurchase Date pursuant to the terms and conditions specified in the
Securities and in this Indenture; and 
  
 the
Security (if such Security is held other than in global form) for cancellation prior to, on or after the Fundamental Change Repurchase Date (together with all necessary endorsements) at the offices of the Paying Agent, such delivery being a
condition to receipt by the Holder of the Fundamental Change Repurchase Price therefor; provided that such Fundamental 

  

 52 

 
Change Repurchase Price shall be so paid pursuant to this Section 11.08 only if the Security so delivered to the Paying Agent shall conform in all respects
to the description thereof in the related Fundamental Change Repurchase Notice. 
  
 The Company shall purchase from the Holder thereof, pursuant to this Section 11.08, a portion of a Security if the Principal Amount of such portion is $1,000 or an integral multiple of $1,000 if so requested by the
Holder. Provisions of this Indenture that apply to the repurchase of all of a Security also apply to the repurchase of such portion of such Security. 
  
 Any repurchase by the Company contemplated pursuant to the provisions of this Section 11.08 shall be consummated by the delivery to the Paying Agent of
the consideration to be received by the Holder promptly following the later of the Fundamental Change Repurchase Date and the time of delivery of the Security. 
  

Notwithstanding anything herein to the contrary, any Holder delivering to the Paying Agent the Fundamental Change Repurchase Notice contemplated by
this Section 11.08(d) shall have the right to withdraw such Fundamental Change Repurchase Notice at any time prior to the close of business on the Business Day prior to the Fundamental Change Repurchase Date by delivery of a written notice of
withdrawal to the Paying Agent in accordance with Section 11.09. 
  
 The Paying Agent shall promptly notify the Company of the receipt by it of any Fundamental Change Repurchase Notice or written notice of withdrawal thereof. 
  
 (e) Payment of Fundamental Change Repurchase Price. The Securities to be repurchased pursuant to this
Section 11.08 shall be paid for in cash; provided that if a Fundamental Change occurs as a result of a Change of Control Event, the Securities to be repurchased may be paid for, in whole or in part, at the election of the Company, in cash or Common
Stock or any combination of cash and Common Stock, subject to the conditions set forth in clause (f) of this Section 11.08. 
  
 (f) Conditions for Election to Pay Fundamental Change Repurchase Price in Common Stock. If the Company elects to pay all or any
portion of the Fundamental Change Repurchase Price in Common Stock, the number of shares of Common Stock to be paid will equal the quotient obtained by dividing (i) the portion of the Fundamental Change Repurchase Price to be paid in shares of
Common Stock by (ii) 97% of the average Closing Price of the shares of Common Stock for the five Trading Day period ending on the second Business Day immediately preceding the Fundamental Change Repurchase Date, appropriately adjusted to take into
account the occurrence, during the period commencing on the first of the Trading Days during the five Trading Day period and ending on the Fundamental Change Repurchase Date, of any event described in Section 13.06, subject to the next succeeding
paragraph. The Company shall designate, in the Fundamental Change Company Notice delivered pursuant to clause (c) of Section 11.08, whether it will repurchase the Securities for cash or shares of Common Stock, or, if a combination thereof, the
percentages of the Fundamental Change Repurchase Price of Securities in respect of which it will pay in cash or shares of Common Stock; provided that the Company will pay cash for fractional interests in shares of Common Stock. For purposes of

  

 53 

 
determining the existence of potential fractional interests, all Securities subject to repurchase by the Company held by a Holder shall be considered
together (no matter how many separate certificates are to be presented). Each Holder whose Securities are repurchased pursuant to this Section 11.08 shall receive the same percentage of cash or shares of Common Stock in payment of the Fundamental
Change Repurchase Price for such Securities, except with regard to the payment of cash in lieu of fractional shares of Common Stock. The Company may not change its election with respect to the consideration (or components or percentages of
components thereof) to be paid once the Company has given its Fundamental Change Company Notice to Holders except as set forth in the next succeeding paragraph in the event of a failure to satisfy, prior to the close of business on the Business Day
prior to the Fundamental Change Repurchase Date, any condition to the payment of the Fundamental Change Repurchase Price, in whole or in part, in shares of Common Stock. 
  
 The Company shall, at least three Business Days prior to delivering the Fundamental Change Company Notice, deliver an
Officers’ Certificate to the Trustee specifying: 
  
 (i) the manner of payment selected by the Company, 
  
 (ii) the information required by the Company Repurchase Notice pursuant to clause (c) of Section 11.08, 
  
 (iii) if the Company elects to pay the Fundamental Change Repurchase Price, or a specified percentage thereof, in shares of Common Stock,
that the conditions to such manner of payment set forth in this clause (f) have been or will be complied with, and 
  
 (iv) whether the Company desires the Trustee to give the Fundamental Change Company Notice required by clause (c) of Section 11.08.

  
 The Company’s right to exercise its election to
repurchase Securities through the issuance of shares of Common Stock shall be conditioned upon: 
  
 (i) the Company’s giving a timely Fundamental Change Company Notice containing an election to purchase all or a specified percentage
of the Securities with shares of Common Stock as provided herein; 
  
 (ii) the registration of such shares of Common Stock under the Securities Act and, if required, the Exchange Act; 
  
 (iii) the listing of such shares of Common Stock on a United States national securities exchange or the quotation of such shares of Common
Stock in an inter-dealer quotation system of any registered United States national securities association, in each case, if the Common Stock is then listed on a national securities exchange or quoted in an inter-dealer quotation system; 

 

 54 

 (iv) any necessary qualification or registration of such shares of Common Stock under
applicable state securities laws or the availability of an exemption from such qualification and registration; and 
  
 (v) the receipt by the Trustee of an (A) Officers’ Certificate stating that the terms of the issuance of the shares of Common Stock
are in conformity with this Indenture, (B) an Opinion of Counsel to the effect that the shares of Common Stock to be issued by the Company in payment of the Fundamental Change Repurchase Price in respect of the Securities have been duly authorized
and, when issued and delivered pursuant to the terms of this Indenture in payment of the Fundamental Change Repurchase Price in respect of the Securities, will be validly issued, fully paid and non-assessable and (c) an Officer’s Certificate,
stating that the conditions to the issuance of the shares of Common Stock have been satisfied. 
  
 Such Officers’ Certificate shall also set forth the number of shares of Common Stock to be issued for each $1,000 principal amount of Securities upon their Stated Maturity and the Closing Price of a share of
Common Stock on each Trading Day during the period commencing on the fifth Trading Day immediately preceding but ending on the third Business Day prior to the applicable Fundamental Change Repurchase Date. If the foregoing conditions are not
satisfied prior to the close of business on the Business Day immediately preceding the Fundamental Change Repurchase Date and the Company has elected to repurchase the Securities through the issuance of shares of Common Stock, the Company shall pay
the entire Fundamental Change Repurchase Price of the Securities in cash. 
  
 Promptly after determination of the actual number of shares of Common Stock to be issued upon repurchase of Securities, the Company shall be required to disseminate a press release through Dow Jones & Company,
Inc. or Bloomberg Business News containing this information or publish the information on the Company’s web site or through such other public medium as the Company may use at that time. 
  
 All shares of Common Stock delivered upon repurchase of the Securities shall
be duly authorized, validly issued, fully paid and nonassessable. 
  
 If a Holder of a repurchased Security is paid in shares of Common Stock, the Company shall pay any documentary, stamp or similar issue or transfer tax due on such issue of Common Stock. However, the Holder shall pay any such tax which is
due because the Holder requests the Common Stock to be issued in a name other than the Holder’s name. The Trustee (or other paying agent appointed by the Company) may refuse to deliver the certificates representing the shares of Common Stock
being issued in a name other than the Holder’s name until the Trustee (or other paying agent appointed by the Company) receives a sum sufficient to pay any tax which will be due because the shares of Common Stock are to be issued in a name
other than the Holder’s name. Nothing herein shall preclude any income tax withholding required by law or regulations. 
  

 55 

 (g) Procedure Upon Repurchase. The Company shall deposit cash or Common Stock, if
permitted hereunder, at the time and in the manner as provided in Section 11.10, sufficient to pay the aggregate Fundamental Change Repurchase Price of all Securities to be purchased pursuant to this Section 11.08. 
  
 Section 11.09. Effect of Fundamental Change Repurchase Notice. Upon
receipt by the Paying Agent of the Fundamental Change Repurchase Notice specified in clause (d) of Section 11.08, the Holder of the Security in respect of which such Fundamental Change Repurchase Notice was given shall (unless such Fundamental
Change Repurchase Notice is withdrawn as specified in the following two paragraphs) thereafter be entitled to receive solely the Fundamental Change Repurchase Price with respect to such Security. Such Fundamental Change Repurchase Price shall be
paid to such Holder, subject to receipt of funds by the Paying Agent, promptly following the later of (x) the Fundamental Change Repurchase Date with respect to such Security (provided the conditions in clause (d) of Section 11.08, have been
satisfied) and (y) the time of delivery of such Security to the Paying Agent by the Holder thereof in the manner required by clause (d) of Section 11.08. Securities in respect of which a Fundamental Change Repurchase Notice has been given by the
Holder thereof may not be converted pursuant to Article 13 on or after the date of the delivery of such Fundamental Change Repurchase Notice unless such Fundamental Change Repurchase Notice has first been validly withdrawn as specified in the
following two paragraphs. 
  
 A Fundamental Change Repurchase
Notice may be withdrawn only by means of a written notice of withdrawal delivered to the office of the Paying Agent in accordance with the procedures set forth in the Fundamental Change Company Notice at any time prior to the close of business on
the Business Day prior to the Fundamental Change Repurchase Date specifying: 
  
 (i) the Principal Amount of the Security with respect to which such notice of withdrawal is being submitted; and 
  
 (ii) the certificate number (if such Security is held in other than global form) of the Security in respect of which such notice of
withdrawal is being submitted; and 
  
 (iii) the
Principal Amount, if any, of such Security which remains subject to the original Fundamental Change Repurchase Notice and which has been or will be delivered for purchase or repurchase by the Company. 
  
 There shall be no repurchase of any Securities pursuant to Section 11.08 if
there has occurred (prior to, on or after, as the case may be, the giving, by the Holders of such Securities, of the required Fundamental Change Repurchase Notice) and is continuing an Event of Default (other than a default in the payment of the
Fundamental Change Repurchase Price with respect to such Securities). The Paying Agent will promptly return to the respective Holders thereof any Securities (x) with respect to which a Fundamental Change Repurchase Notice has been withdrawn in
compliance with this Indenture, or (y) held by it during the continuance of an 

  

 56 

 
Event of Default (other than a default in the payment of the Fundamental Change Repurchase Price with respect to such Securities) in which case, upon such
return, the Fundamental Change Repurchase Notice with respect thereto shall be deemed to have been withdrawn. 
  
 Section 11.10. Deposit of Fundamental Change Repurchase Price. Prior to 10:00 a.m. (local time in The City of New York) on the Business Day
preceding the Fundamental Change Repurchase Date, the Company shall deposit with the Trustee or with the Paying Agent (or, if the Company or a Subsidiary or an Affiliate of either of them is acting as the Paying Agent, shall segregate and hold in
trust as provided herein) an amount of money (in immediately available funds if deposited on such Business Day) or Common Stock, if permitted hereunder, sufficient to pay the Fundamental Change Repurchase Price of all the Securities or portions
thereof which are to be repurchased as of the Fundamental Change Repurchase Date. The Company shall promptly notify the Trustee in writing of the amount of any deposits of cash or Common Stock made pursuant to Section 11.10. 
  
 Section 11.11. Securities Repurchased in Whole or in Part. Any
Security which is to be repurchased, whether in whole or in part, shall be surrendered at the office of the Paying Agent (with, if the Company or the Trustee so requires, due endorsement by, or a written instrument of transfer in form satisfactory
to the Company and the Trustee duly executed by, the Holder thereof or such Holder’s attorney duly authorized in writing) and the Company shall execute and the Trustee shall authenticate and deliver to the Holder of such Security, without
service charge, a new Security or Securities, of any authorized denomination as requested by such Holder in aggregate Principal Amount equal to, and in exchange for, the portion of the Principal Amount of the Security so surrendered which is not
repurchased. 
  
 Section 11.12. Covenant to Comply With
Securities Laws Upon Repurchase of Securities. In connection with any offer to repurchase Securities under Section 11.08 (provided that such offer or repurchase constitutes an “issuer tender offer” for purposes of Rule 13e-4 (which
term, as used herein, includes any successor provision thereto) under the Exchange Act at the time of such offer or repurchase), the Company shall (i) comply with Rule 13e-4 and Rule 14e-1 under the Exchange Act, (ii) file the related Schedule TO
(or any successor schedule, form or report) under the Exchange Act, and (iii) otherwise comply with all Federal and state securities laws so as to permit the rights and obligations under Section 11.08 to be exercised in the time and in the manner
specified in Section 11.08, as applicable. 
  
 Section 11.13.
Repayment to the Company. The Trustee and the Paying Agent shall return to the Company any cash that remains unclaimed, together with interest or dividends, if any, thereon, held by them for the payment of the Fundamental Change Repurchase
Price; provided that to the extent that the aggregate amount of cash or Common Stock deposited by the Company pursuant to Section 11.10 exceeds the aggregate Fundamental Change Repurchase Price of the Securities or portions thereof 

  

 57 

 
which the Company is obligated to repurchase as of the Fundamental Change Repurchase Date, then as soon as practicable following the Fundamental Change
Repurchase Date, the Trustee or the Paying Agent, as the case may be, shall return any such excess to the Company. 
  
 ARTICLE 12 
 Interest Payments on the Securities 
  
 Section 12.01. Interest Rate. (a) Interest on the Securities shall
accrue at a rate of 31⁄2% per annum and shall be payable semi-annually in arrears on each Interest Payment Date to Holders of record on the Record Date immediately preceding such Interest Payment Date. Interest will be computed on the basis of a
360-day year comprised of twelve 30-day months. Interest on the Securities shall accrue from the most recent date to which interest has been paid, or if no interest has been paid, from May 10, 2004, until the Principal Amount is paid or duly made
available for payment. 
  
 (b) Interest on any
Security that is payable, and is punctually paid or duly provided for, on any Interest Payment Date shall be paid to the Person in whose name that Security is registered at the close of business on the Record Date for such interest at the office or
agency of the Company maintained for such purpose. Each installment of interest on any Security shall be made by check mailed to the address of the Holder specified in the register of Securities; provided, however, that, with respect to any Holder
of Securities with an aggregate principal amount in excess of $2,000,000, at the request of such Holder in writing to the Company, interest on such Holder’s Securities shall be paid by wire transfer in immediately available funds in accordance
with the written wire transfer instruction supplied by such Holder from time to time to the Trustee and Paying Agent (if different from the Trustee) at least ten days prior to the applicable Interest Payment Date. In the case of a permanent Global
Security, interest payable on any Interest Payment Date will be paid to the Depositary, with respect to that portion of such permanent Global Security held for its account by Cede & Co. for the purpose of permitting such party to credit the
interest received by it in respect of such permanent Global Security to the accounts of the beneficial owners thereof. 
  
 ARTICLE 13 
 Conversion 
  
 Section 13.01. Conversion Privilege. (a) Subject to the further
provisions of this Article 13, a Holder of a Security may convert the Principal Amount of such Security (or a portion thereof equal to $1,000 or any integral multiple of $1,000 in excess thereof) into Common Stock at any time prior to the close of
business on the Business Day prior to the Stated Maturity. 
  
 (b) Conversion Period. Notwithstanding the foregoing, if such Security is submitted or presented for repurchase pursuant to Article 11, such conversion right shall terminate at the close of business on the
Business Day prior to the Fundamental Change Repurchase Date for such Security or such earlier date as the Holder presents such Security for 

  

 58 

 
repurchase (unless the Company shall default when due, in which case the conversion right shall terminate at the close of business on the date such default
is cured and such Security is repurchased). 
  
 (c) Conversion Rate; Conversion Price. The conversion rate per Security (the “Conversion Rate”) shall be that set forth in paragraph 5 in the Securities, subject to adjustment as herein set forth. The initial
Conversion Rate is 150.5571 shares of Common Stock per $1,000 principal amount of Securities. The “Conversion Price” at any particular time is determined by dividing $1,000 by the then-applicable Conversion Rate. 
  
 (d) Securities Converted in Whole or in Part.
Provisions of this Indenture that apply to conversion of all of a Security also apply to conversion of a portion of a Security. 
  
 (e) Rights of Holders. A Holder of Securities is not entitled to any rights of a holder of Common Stock until such Holder has
converted its Securities to Common Stock, and only to the extent such Securities are deemed to have been converted into Common Stock pursuant to this Article 13. 
  
 Section 13.02. Conversion Procedure. 
  
 (a) To convert a Security, a Holder must (i) complete and manually sign the conversion notice on the back of
the Security or facsimile of the conversion notice and deliver such notice to a Conversion Agent, (ii) surrender the Security to a Conversion Agent, (iii) furnish appropriate endorsements and transfer documents if required by a Registrar or a
Conversion Agent and (iv) pay any transfer or similar tax, if required. Such notice is hereinafter referred to as a “Notice of Conversion.” A Security shall be deemed to have been converted as of the close of business on the date
(the “Conversion Date”) on which the Holder has complied with the immediately preceding sentence of this clause (a) of Section 13.02. Anything herein to the contrary notwithstanding, in the case of Global Securities, a Notice of
Conversion shall be delivered and such Securities shall be surrendered for conversion in accordance with the rules and procedures of DTC as in effect from time to time. 
  
 (b) The Company will, as soon as practicable after the Conversion Date, issue, or cause to be issued, and
deliver to the Conversion Agent or to such Holder, or such Holder’s nominee or nominees, certificates for the number of full shares of Common Stock, if any, to which such Holder shall be entitled. The Person or Persons entitled to receive such
Common Stock upon such conversion shall be treated for all purposes as the record holder or holders of such Common Stock, as of the close of business on the applicable Conversion Date; provided, however, that no surrender of a Security on any date
when the stock transfer books of the Company shall be closed shall be effective to constitute the Person or Persons entitled to receive the shares of Common Stock upon such conversion as the record holder or holders of such shares of Common Stock on
such date, but such surrender shall be effective to constitute the Person or Persons entitled to receive such shares of Common Stock as the record holder or holders thereof for all purposes at the close of business on the next succeeding day on
which 

  

 59 

 
such stock transfer books are open; provided further that such conversion shall be at the Conversion Rate in effect on the Conversion Date as if the stock
transfer books of the Company had not been closed. Upon conversion of a Security, such Person shall no longer be a Holder of such Security. Except as otherwise provided in Section 13.06, no payment or adjustment will be made for dividends or
distributions on shares of Common Stock issued upon conversion of a Security. 
  
 All Securities or portions thereof surrendered for conversion during the period from the close of business on the Record Date for any Interest Payment Date to the close of business on the Business Day next preceding
the following Interest Payment Date shall (unless such Securities or portion thereof being converted shall have been called for redemption on a Redemption Date which occurs during the period from the close of business on such Record Date to the
close of business on the Business Day next preceding the following Interest Payment Date) be accompanied by payment, in funds acceptable to the Company, of an amount equal to the interest otherwise payable on such Interest Payment Date on the
Principal Amount being converted; provided, however, that no such payment need be made if there shall exist at the time of conversion a default in the payment of interest on the Securities. 
  
 (c) If a Holder converts more than one Security at the same
time, the number of shares of Common Stock issuable upon the conversion shall be based on the aggregate Principal Amount of Securities converted. 
  
 (d) Upon surrender of a Security that is converted in part, the Company shall execute, and the Trustee shall authenticate and deliver to
the Holder, a new Security equal in principal amount to the unconverted portion of the Security surrendered. 
  
 (e) If the last day on which Security may be converted is not a Business Day in a place where a Conversion Agent is located, the
Securities may be surrendered to that Conversion Agent on the next succeeding Business Day. 
  
 (f) Holders that have already delivered a Fundamental Change Repurchase Notice with respect to a Security may not surrender such Security
for conversion until the Fundamental Change Repurchase Notice has been withdrawn in accordance with the procedures set forth in Section 11.09. 
  
 Section 13.03. Fractional Shares. The Company will not issue fractional shares of Common Stock upon conversion of Securities. In lieu thereof, the
Company will pay an amount in cash for the current market value of the fractional shares. The current market value of a fractional share shall be determined, (calculated to the nearest 1/1000th of a share) by multiplying the Closing Price of the
Common Stock on the Trading Day immediately prior to the Conversion Date by such fractional share and rounding the product to the nearest whole cent. 
  
 Section 13.04. Taxes on Conversion. If a Holder converts a Security, the Company shall pay any documentary, stamp or similar issue or transfer tax
due on the 

  

 60 

 
issuance of shares of Common Stock upon such conversion. However, the Holder shall pay any such tax which is due because the Holder requests the shares to be
issued in a name other than the Holder’s name. The Conversion Agent may refuse to deliver the certificate representing the Common Stock being issued in a name other than the Holder’s name until the Conversion Agent receives a sum
sufficient to pay any tax which will be due because the shares are to be issued in a name other than the Holder’s name. Nothing herein shall preclude any tax withholding required by law or regulation. 
  
 Section 13.05. Company to Provide Stock. 
  
 (a) The Company shall, prior to issuance of any Securities
hereunder, and from time to time as may be necessary, reserve, out of its authorized but unissued Common Stock, a sufficient number of shares of Common Stock to permit the conversion of all outstanding Securities into shares of Common Stock
(including after taking into account any adjustments to the Conversion Rate pursuant to Section 13.06). 
  
 (b) All shares of Common Stock delivered upon conversion of the Securities shall be newly issued shares, shall be duly authorized, validly
issued, fully paid and nonassessable and shall be free from preemptive rights and free of any lien or adverse claim. 
  
 (c) The Company will endeavor promptly to comply with all federal and state securities laws regulating the offer and delivery of shares of
Common Stock upon conversion of Securities, if any, and will list or cause to have quoted such shares of Common Stock on each national securities exchange or on the New York Stock Exchange, the Nasdaq National Market or other over-the-counter market
or such other market on which the Common Stock is then listed or quoted; provided, however, that if rules of such automated quotation system or exchange permit the Company to defer the listing of such Common Stock until the first conversion of the
Securities into Common Stock in accordance with the provisions of this Indenture, the Company covenants to list such Common Stock issuable upon conversion of the Securities in accordance with the requirements of such automated quotation system or
exchange at such time. Any Common Stock issued upon conversion of a Security hereunder which at the time of conversion was a Transfer Restricted Security will remain a Transfer Restricted Security. 
  
 Section 13.06. Adjustment of Conversion Rate. The Conversion Rate
shall be adjusted from time to time by the Company as follows: 
  
 (a) In case the Company shall (i) pay a dividend on its Common Stock in shares of Common Stock, (ii) make a distribution on its Common Stock in shares of Common Stock, (iii) subdivide its outstanding Common Stock into
a greater number of shares, or (iv) combine its outstanding Common Stock into a smaller number of shares, the Conversion Rate in effect immediately prior thereto shall be adjusted so that the Holder of any Security thereafter surrendered for
conversion shall be entitled to receive that number of shares of Common Stock which it would have owned had such Security been converted immediately prior to the happening of such event. An adjustment made pursuant to this subsection (a) shall
become 

  

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effective immediately after the record date in the case of a dividend or distribution and shall become effective immediately after the effective date in the
case of subdivision or combination. 
  
 (b) In
case the Company shall issue rights or warrants (other than pursuant to a stockholder rights plan) to all or substantially all holders of its Common Stock entitling them (for a period commencing no earlier than the record date described below and
expiring not more than 60 days after such record date) to subscribe for or purchase shares of Common Stock (or securities convertible into Common Stock) at a price per share (or having a conversion price per share) less than the Closing Price per
share of Common Stock on the Business Day immediately prior to the date of announcement of such issuance, the Conversion Rate in effect shall be adjusted so that the same shall equal the rate determined by multiplying the Conversion Rate in effect
immediately prior to such announcement by a fraction of which the numerator shall be the number of shares of Common Stock outstanding at the close of business on the date of announcement plus the number of additional shares of Common Stock offered
(or into which the convertible securities so offered are convertible), and the denominator of which shall be the number of shares of Common Stock outstanding at the close of business on the date of announcement plus the number of shares which the
aggregate offering price of the total number of shares of Common Stock so offered (or the aggregate conversion price of the convertible securities so offered, which shall be determined by multiplying the number of shares of Common Stock issuable
upon conversion of such convertible securities by the conversion price per share of Common Stock pursuant to the terms of such convertible securities) would purchase at the Current Market Price per share of Common Stock on the Business Day
immediately preceding the date of announcement of such issuance. Such adjustment shall be made successively whenever any such rights or warrants are issued, and shall become effective on the day following the date of announcement of such issuance.
If at the end of the period during which such rights or warrants are exercisable not all rights or warrants shall have been exercised, the adjusted Conversion Rate shall be immediately readjusted to what it would have been based upon the number of
additional shares of Common Stock actually issued (or the number of shares of Common Stock issuable upon conversion of convertible securities actually issued). 
  

(c) In case the Company shall distribute to all or substantially all holders of its Common Stock any shares of capital stock of the
Company (other than Common Stock), evidences of indebtedness or other non-cash assets (including securities of any person other than the Company but excluding (1) dividends or distributions paid exclusively in cash or (2) dividends or distributions
referred to in subsection (a) of this Section 13.06), or shall distribute to all or substantially all holders of its Common Stock rights or warrants to subscribe for or purchase any of its securities (excluding those rights and warrants referred to
in subsection (b) of this Section 13.06 and also excluding the distribution of rights to all holders of Common Stock pursuant to a Rights Plan (as defined below) or the detachment of such rights to the extent set forth in the second following
paragraph), then in each such case the Conversion Rate shall be adjusted so that the same shall equal the rate determined by multiplying the current Conversion Rate by a fraction of which the numerator shall be the Current Market Price per share of
the Common Stock on the record date mentioned below and the denominator shall be 

  

 62 

 
the Current Market Price per share of the Common Stock on such record date less the fair market value on such record date (as determined by the Board of
Directors, whose determination shall be conclusive evidence of such fair market value and which shall be evidenced by an Officers’ Certificate delivered to the Trustee) of the portion of the capital stock, evidences of indebtedness or other
non-cash assets so distributed or of such rights or warrants applicable to one share of Common Stock (determined on the basis of the number of shares of Common Stock outstanding on the record date). Such adjustment shall be made successively
whenever any such distribution is made and shall become effective immediately after the record date for the determination of shareholders entitled to receive such distribution. 
  
 In the event the then fair market value (as so determined) of the portion of the Capital Stock, evidences of indebtedness or
other non-cash assets so distributed or of such rights or warrants applicable to one share of Common Stock is equal to or greater than the Current Market Price per share of the Common Stock on such record date, in lieu of the foregoing adjustment,
adequate provision shall be made so that each Holder of a Security shall have the right to receive upon conversion the amount of Capital Stock, evidences of indebtedness or other non-cash assets so distributed or of such rights or warrants such
Holder would have received had such Holder converted each Security on such record date. In the event that such dividend or distribution is not so paid or made, the Conversion Rate shall again be adjusted to be the Conversion Rate which would then be
in effect if such dividend or distribution had not been declared. If the Board of Directors determines the fair market value of any distribution for purposes of this Section 13.06 by reference to the actual or when issued trading market for any
securities, it must in doing so consider the prices in such market over the same period used in computing the Current Market Price of the Common Stock. 
  
 In the event that the Company has in effect a preferred shares rights plan (“Rights Plan”), upon conversion of the Securities into Common
Stock, to the extent that the Rights Plan is still in effect upon such conversion, the Holders of Securities will receive, in addition to the Common Stock, the rights described therein (whether or not the rights have separated from the Common Stock
at the time of conversion), subject to the limitations set forth in the Rights Plan. If the Rights Plan provides that upon separation of rights under such plan from the Company’s Common Stock that the Holders would not be entitled to receive
any such rights in respect of the Common Stock issuable upon conversion of the Securities, the Conversion Rate will be adjusted as provided in this Section 13.06(c) (with such separation deemed to be the distribution of such rights), subject to
readjustment in the event of the expiration, termination or redemption of the rights. Any distribution of rights or warrants pursuant to a Rights Plan that would allow a Holder to receive upon conversion, in addition to the Common Stock, the rights
described therein (whether or not the rights have separated from the Common Stock at the time of conversion), shall not constitute a distribution of rights or warrants pursuant to this Article 13. 
  
 Rights or warrants distributed by the Company to all holders of Common Stock
entitling the holders thereof to subscribe for or purchase shares of the Company’s Capital Stock (either initially or under certain circumstances), which rights or warrants, until the occurrence of a specified event or events (“Trigger
Event”): (i) are deemed to be transferred with such shares 

  

 63 

 
of Common Stock; (ii) are not exercisable; and (iii) are also issued in respect of future issuances of Common Stock, shall be deemed not to have been
distributed for purposes of this Section 13.06 (and no adjustment to the Conversion Rate under this Section 13.06 will be required) until the occurrence of the earliest Trigger Event, whereupon such rights and warrants shall be deemed to have been
distributed and an appropriate adjustment (if any is required) to the Conversion Rate shall be made under this clause (c) of Section 13.06. If any such right or warrant, including any such existing rights or warrants distributed prior to the date of
this Indenture, are subject to events, upon the occurrence of which such rights or warrants become exercisable to purchase different securities, evidences of indebtedness or other assets, then the date of the occurrence of any and each such event
shall be deemed to be the date of distribution and record date with respect to new rights or warrants with such rights (and a termination or expiration of the existing rights or warrants without exercise by any of the holders thereof). In addition,
in the event of any distribution (or deemed distribution) of rights or warrants, or any Trigger Event or other event (of the type described in the preceding sentence) with respect thereto that was counted for purposes of calculating a distribution
amount for which an adjustment to the Conversion Rate under this Section 13.06 was made, (1) in the case of any such rights or warrants which shall all have been redeemed or repurchased without exercise by any holders thereof, the Conversion Rate
shall be readjusted upon such final redemption or repurchase to give effect to such distribution or Trigger Event, as the case may be, as though it were a cash distribution, equal to the per share redemption or repurchase price received by a holder
or holders of Common Stock with respect to such rights or warrants (assuming such holder had retained such rights or warrants), made to all holders of Common Stock as of the date of such redemption or repurchase, and (2) in the case of such rights
or warrants which shall have expired or been terminated without exercise by any holders thereof, the Conversion Rate shall be readjusted as if such rights and warrants had not been issued. 
  
 (d) In case the Company shall, by dividend or otherwise, at
any time distribute (a “Triggering Distribution”) to all or substantially all holders of its Common Stock cash, the Conversion Rate shall be increased so that the same shall equal the rate determined by multiplying such Conversion
Rate in effect on the Business Day immediately prior to the record date (the “Determination Date”) for such Triggering Distribution is declared by the Company by a fraction of which the numerator shall be the Current Market Price
per share of the Common Stock on the Determination Date, and the denominator shall be the Current Market Price per share of the Common Stock on the Determination Date less the aggregate amount of cash so distributed applicable to one share of Common
Stock (determined on the basis of the number of shares of Common Stock outstanding on the date such distribution is made), such increase to become effective immediately prior to the opening of business on the day following the date on which the
Triggering Distribution is paid. It is expressly understood that a stock buyback, repurchase or similar transaction or program shall in no event be considered a Triggering Distribution for purposes of this clause (d) or (e) of Section 13.06.

  
 (e) In case the Company or any of its
Subsidiaries shall purchase any shares of the Company’s Common Stock by means of a tender offer, then, effective immediately prior to the opening of business on the day after the last date (the “Expiration Date”) tenders

  

 64 

 
could have been made pursuant to such tender offer (as it may be amended) (the last time at which such tenders could have been made on the Expiration Date is
hereinafter sometimes called the “Expiration Time”), the Conversion Rate shall be increased so that the same shall equal the rate determined by multiplying the Conversion Rate in effect immediately prior to the close of business on
the Expiration Date by a fraction of which the numerator shall be the sum of (x) the aggregate consideration (determined as set forth below) payable to stockholders of the Company based on the acceptance (up to any maximum specified in the terms of
the tender offer) of all shares validly tendered and not withdrawn as of the Expiration Time (the shares deemed so accepted, up to any such maximum, being referred to as the “Purchased Shares”) and (y) the product of the number of
shares of Common Stock outstanding (less any Purchased Shares and excluding any shares held in the treasury of the Company) immediately prior to the Expiration Time and the Current Market Price per share of Common Stock (as determined in accordance
with clause (f) of Section 13.06), and the denominator shall be the product of the number of shares of Common Stock outstanding (including Purchased Shares but excluding any shares held in the treasury of the Company) immediately prior to the
Expiration Time multiplied by the Current Market Price per share of the Common Stock (as determined in accordance with clause (f) of Section 13.06). For purposes of this clause (e) of Section 13.06, the aggregate consideration in any such tender
offer shall equal the sum of the aggregate amount of cash consideration and the aggregate fair market value (as determined by the Board of Directors, whose determination shall be conclusive evidence thereof and which shall be evidenced by an
Officers’ Certificate delivered to the Trustee) of any other consideration payable in such tender offer. In the event that the Company is obligated to purchase shares pursuant to any such tender offer, but the Company is permanently prevented
by applicable law from effecting any or all such purchases or any or all such purchases are rescinded, the Conversion Rate shall again be adjusted to be the Conversion Rate which would have been in effect based upon the number of shares actually
purchased. If the application of this clause (e) of Section 13.06 to any tender offer would result in a decrease in the Conversion Rate, no adjustment shall be made for such tender offer under this Section 13.06(e). For purposes of this clause (e)
of Section 13.06, the term “tender offer” shall mean and include both tender offers and exchange offers, all references to “purchases” of shares in tender offers (and all similar references) shall mean and include both the
purchase of shares in tender offers and the acquisition of shares pursuant to exchange offers, and all references to “tendered shares” (and all similar references) shall mean and include shares tendered in both tender offers and exchange
offers. 
  
 (f) For the purpose of any
computation under clauses (b), (c) and (d) of Section 13.06, the current market price (the “Current Market Price”) per share of Common Stock on any date shall be deemed to be the average of the daily Closing Prices for the ten
consecutive Trading Days commencing 11 Trading Days before the record date with respect to distributions, issuances or other events requiring such computation under Section 13.06. For purposes of any computation under subsection (e) of this Section
13.06, the Current Market Price per share of Common Stock shall be deemed to be the average of the daily Closing Prices for the ten consecutive Trading Days commencing on the Trading Day next succeeding the Expiration Date. 
  

 65 

 (g) In any case in which this Section 13.06 shall require that an adjustment be made
following a record date, an announcement date or a Determination Date or Expiration Date, as the case may be, established for purposes of this Section 13.06, the Company may elect to defer (but only until five Business Days following the filing by
the Company with the Trustee of the certificate described in Section 13.09) issuing to the Holder of any Security converted after such record date or announcement date or Determination Date or Expiration Date the shares of Common Stock and other
capital stock of the Company issuable upon such conversion over and above the shares of Common Stock and other capital stock of the Company issuable upon such conversion only on the basis of the Conversion Rate prior to adjustment; and, in lieu of
the shares the issuance of which is so deferred, the Company shall issue or cause its transfer agents to issue due bills or other appropriate evidence prepared by the Company of the right to receive such shares. If any distribution in respect of
which an adjustment to the Conversion Rate is required to be made as of the record date or announcement date or Determination Date or Expiration Date therefor is not thereafter made or paid by the Company for any reason, the Conversion Rate shall be
readjusted to the Conversion Rate which would then be in effect if such record date had not been fixed or such announcement date or effective date or Determination Date or Expiration Date had not occurred. 
  
 Section 13.07. No Adjustment. (a) No adjustment need be made for
issuances of Common Stock pursuant to a Company plan for reinvestment of dividends or interest or for a change in the par value or a change to no par value of the Common Stock. 
  
 (b) To the extent that the Securities become convertible into the right to receive cash, no adjustment need
be made thereafter as to the cash. Interest will not accrue on the cash due. 
  
 (c) No adjustment in the Conversion Rate shall be made pursuant to this Section 13.06 if the Holders may participate in the transaction that would otherwise give rise to an adjustment pursuant to Section 13.06.

  
 (d) Other than as described above in Section
13.06, no adjustment to the Conversion Rate shall be required for any issuance of Common Stock or convertible or exchangeable securities or rights to purchase Common Stock or convertible or exchangeable securities. 
  
 (e) No adjustment in the Conversion Rate shall be made
pursuant to Section 13.06 unless the adjustment would require a change of at least 1% of the Conversion Rate in effect immediately prior to the event otherwise giving rise to such adjustment; provided, however, that any such events for which
adjustments are not made pursuant to this sentence shall be carried forward and such adjustment shall be made at such time as the aggregate amount of all such adjustments heretofore not made would require an adjustment equal to or in excess of 1% of
the Conversion Rate in effect immediately prior to the first of such events. 
  

 66 

 Section 13.08. Adjustment for Tax Purposes. The Company shall be entitled to make such increases
in the Conversion Rate, in addition to those required by Section 13.06, as it in its discretion shall determine to be advisable in order that any stock dividends, subdivisions of shares, distributions of rights to purchase stock or securities or
distributions of securities convertible into or exchangeable for stock hereafter made by the Company to its stockholders shall not be taxable. 
  
 Section 13.09. Notice of Conversion Rate Adjustment. Whenever the Conversion Rate is adjusted, the Company shall promptly mail to Securityholders a
notice of the adjustment and file with the Trustee an Officers’ Certificate briefly stating the facts requiring the adjustment and the manner of computing it. Unless and until the Trustee shall receive an Officers’ Certificate setting
forth an adjustment of the Conversion Rate, the Trustee may assume without inquiry that the Conversion Rate has not been adjusted and that the last Conversion Rate of which it has knowledge remains in effect. 
  
 Section 13.10. Notice of Certain Transactions. In the event that:

  
 (a) the Company takes any action which would
require an adjustment in the Conversion Rate; 
  
 (b) the Company consolidates or merges with, or transfers all or substantially all of its property and assets to, another corporation and shareholders of the Company must approve the transaction; or 
  
 (c) there is a dissolution or liquidation of the Company,

  
 the Company shall mail to Holders and file with the Trustee a notice stating
the proposed record or effective date, as the case may be. The Company shall mail the notice at least ten days before such date. Failure to mail such notice or any defect therein shall not affect the validity of any transaction referred to in clause
(a), (b) or (c) of this Section 13.10. 
  
 Section 13.11.
Effect of Reclassification, Consolidation, Merger or Sale on Conversion Privilege. If any of the following shall occur, namely: (a) any reclassification or change of shares of Common Stock issuable upon conversion of the Securities (other
than a change in par value, or from par value to no par value, or from no par value to par value, or as a result of a subdivision or combination, or any other change for which an adjustment is provided in Section 13.06); (b) any consolidation or
merger or combination to which the Company is a party other than a merger in which the Company is the continuing corporation and which does not result in any reclassification of, or change (other than in par value, or from par value to no par value,
or from no par value to par value, or as a result of a subdivision or combination) in, outstanding shares of Common Stock; or (c) any sale or conveyance as an entirety or substantially as an entirety of the property and assets of the Company,
directly or indirectly, to any Person, then the Company, or such successor, purchasing or transferee corporation, as the case 

  

 67 

 
may be, shall, as a condition precedent to such reclassification, change, combination, consolidation, merger, sale or conveyance, execute and deliver to the
Trustee a supplemental indenture providing that the Holder of each Security then outstanding shall have the right to convert such Security into the kind and amount of shares of stock and other securities and property (including cash) receivable upon
such reclassification, change, combination, consolidation, merger, sale or conveyance by a holder of the number of shares of Common Stock deliverable upon conversion of such Security immediately prior to such reclassification, change, combination,
consolidation, merger, sale or conveyance. Such supplemental indenture shall provide for adjustments of the Conversion Rate which shall be as nearly equivalent as may be practicable to the adjustments of the Conversion Rate provided for in this
Article 13. If, in the case of any such consolidation, merger, combination, sale or conveyance, the stock or other securities and property (including cash) receivable thereupon by a holder of Common Stock include shares of stock or other securities
and property of a person other than the successor, purchasing or transferee corporation, as the case may be, in such consolidation, merger, combination, sale or conveyance, then such supplemental indenture shall also be executed by such other person
and shall contain such additional provisions to protect the interests of the Holders of the Securities as the Board of Directors shall reasonably consider necessary by reason of the foregoing. The provisions of this Section 13.11 shall similarly
apply to successive reclassifications, changes, combinations, consolidations, mergers, sales or conveyances. 
  
 In the event the Company shall execute a supplemental indenture pursuant to this Section 13.11, the Company shall promptly file with the Trustee (x) an
Officers’ Certificate briefly stating the reasons therefor, the kind or amount of shares of stock or other securities or property (including cash) receivable by Holders of the Securities upon the conversion of their Securities after any such
reclassification, change, combination, consolidation, merger, sale or conveyance, any adjustment to be made with respect thereto and that all conditions precedent have been complied with and (y) an Opinion of Counsel that all conditions precedent
have been complied with, and shall promptly mail notice thereof to all Holders. 
  
 Section 13.12. Trustee’s Disclaimer. The Trustee shall have no duty to determine when an adjustment under this Article 13 should be made, how it should be made or what such adjustment should be, but may
accept as conclusive evidence of that fact or the correctness of any such adjustment, and shall be protected in relying upon, an Officers’ Certificate including the Officers’ Certificate with respect thereto which the Company is obligated
to file with the Trustee pursuant to Section 13.09. The Trustee makes no representation as to the validity or value of any securities or assets issued upon conversion of Securities and the Trustee shall not be responsible for the Company’s
failure to comply with any provisions of this Article 13. 
  
 The
Trustee shall not be under any responsibility to determine the correctness of any provisions contained in any supplemental indenture executed pursuant to Section 13.11, but may accept as conclusive evidence of the correctness thereof, and shall be
fully protected in relying 

  

 68 

 
upon, the Officers’ Certificate with respect thereto which the Company is obligated to file with the Trustee pursuant to Section 13.11. 
  
 Section 13.13. Voluntary Increase. The Company from time to time may
increase the Conversion Rate by any amount for any period of time if the period is at least 20 days and if the increase is irrevocable during the period if the Board of Directors determines that such increase would be in the best interest of the
Company or the Board of Directors deems it advisable to avoid or diminish income tax to holders of shares of our Common Stock in connection with any stock or rights dividend or distribution or similar event, and the Company provides 15 days prior
notice of any increase in the Conversion Rate. 
  
 Section 13.14.
Company Determination Final. Any determination that the Company or the Board of Directors must make pursuant to this Article 13 shall be conclusive if made in good faith and in accordance with the provisions of this Article 13, absent
manifest error, and set forth in a resolution of the Board of Directors. 
  
 ARTICLE 14 
 Collateral Security 
  
 Section 14.01. Collateral Security. 
  
 (a) Upon the Closing Date (as defined in the Purchase Agreement), the Company shall (i) enter into the Pledge Agreement and thereafter
comply with the terms and provisions of such agreement and (ii) pledge the Pledged Securities to the Pledged Securities Intermediary for the benefit of the Trustee and the ratable benefit of the Holders in such amount as will be sufficient upon
receipt of scheduled interest and/or principal payments of such Pledged Securities to provide for payment in full of the first six scheduled interest payments due on the Securities, but excluding the Liquidated Damages, if any. The Pledged
Securities shall be pledged by the Company to the Pledged Securities Intermediary for the benefit of the Trustee and the ratable benefit of the Holders and shall be held by the Pledged Securities Intermediary in the Pledge Account pending
disposition pursuant to the Pledge Agreement. The Pledged Securities shall also secure the payment of the Principal Amount and Liquidated Damages, if any, due on the Securities subject to the terms and conditions set forth in Section 13 of the
Pledge Agreement. 
  
 (b) Each Holder, by its
acceptance of a Security, consents and agrees to the terms of the Pledge Agreement (including, without limitation, the provisions providing for foreclosure and release of the Pledged Securities) as such agreement may be in effect or may be amended
from time to time in accordance with their terms, and authorizes and directs the Pledged Securities Intermediary and the Trustee to enter into the Pledge Agreement and to perform their respective obligations and exercise their respective rights
under such agreement in accordance therewith. The Company will do or cause to be done all such acts and things as may be necessary or reasonably requested by the Pledged Securities Intermediary or the Trustee, or as may be required by the provisions
of the Pledge Agreement, to assure and confirm to the Pledged 

  

 69 

 
Securities Intermediary and the Trustee the security interest in the Pledged Securities contemplated hereby, by the Pledge Agreement or any part of such
agreement, as from time to time constituted, so as to render the same available for the security and benefit of this Indenture and of the Securities secured hereby, according to the intent and purposes herein and therein expressed. The Company shall
take, or cause to be taken, upon request of the Pledged Securities Intermediary or the Trustee, any and all actions reasonably required to create and maintain, as security for the obligations of the Company under this Indenture and the Securities, a
valid, enforceable and perfected first priority Lien in and on all the Pledged Securities, in favor of the Pledged Securities Intermediary for the benefit of the Trustee and the ratable benefit of the Holders, superior to and prior to the rights of
third Persons and subject to no other Liens. 
  
 (c) The release of any portion of the Pledged Securities pursuant to the Pledge Agreement will not be deemed to impair the security under this Indenture in contravention of the provisions hereof if and to the extent the Pledged Securities
are released pursuant to this Indenture and the Pledge Agreement. To the extent applicable, the Company shall cause TIA Section 314(d) relating to the release of property or securities from the Lien and security interest of the Pledge Agreement and
relating to the substitution therefore of any property or securities to be subjected to the Lien and security interest of the Pledge Agreement to be complied with. Any certificate or opinion required by TIA Section 314(d) may be made by an Officer
of the Company, except in cases where TIA Section 314(d) requires that such certificate or opinion be made by an independent Person, which Person shall be an independent engineer, appraiser or other expert selected by the Company. 
  
 (d) The Company shall cause TIA Section 314(b), relating to
opinions of counsel regarding the Lien under the Pledge Agreement, to be complied with. The Pledged Securities Intermediary and the Trustee may accept, to the extent permitted by Sections 4.4 and 7.6 as conclusive evidence of compliance with the
foregoing provisions, the appropriate statements contained in such instruments. 
  
 (e) The Pledged Securities Intermediary and the Trustee may, in their sole discretion and without the consent of the Holders, on behalf of
the Holders, take all reasonable actions in accordance with the Pledge Agreement, necessary or appropriate in order to (i) enforce any of the terms of the Pledge Agreement and (ii) collect and receive any and all amounts payable in respect of the
obligations of the Company under such agreement. The Pledged Securities Intermediary and the Trustee shall have power to institute and to maintain such suits and proceedings as the they may reasonably deem expedient to preserve or protect their
interests and the interests of the Holders in the Pledged Securities (including power to institute and maintain suits or proceedings to restrain the enforcement of or compliance with any legislative or other governmental enactment, rule or order
that may be unconstitutional or otherwise invalid if the enforcement of, or compliance with, such enactment, rule or order would impair the security interest hereunder or be prejudicial to the interests of the Holders, the Pledged Securities
Intermediary or of the Trustee). 
  

 70 

 IN WITNESS WHEREOF, the parties hereto have caused this Indenture to be duly executed as of the day and
year first above written. 
  

			
	OSCIENT PHARMACEUTICALS CORPORATION
		
	By:	 	/s/    STEPHEN COHEN
	Name:	 	Stephen Cohen
	Title:	 	Senior Vice President and CFO

  

			
	 U.S. BANK NATIONAL ASSOCIATION,
 as
Trustee

		
	By:	 	/s/    ALISON D.B. NADEAU
	Name:	 	Alison D.B. Nadeau
	Title:	 	Vice President

  

 71 

 EXHIBIT A 
  

FORM OF FACE OF SECURITY 
  
 [INCLUDE IF SECURITY IS A RESTRICTED SECURITY — THIS SECURITY (OR ITS PREDECESSOR) WAS ORIGINALLY ISSUED IN A TRANSACTION EXEMPT FROM
REGISTRATION UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND THIS SECURITY AND THE COMMON STOCK ISSUABLE UPON CONVERSION HEREOF MAY NOT BE OFFERED, SOLD OR OTHERWISE TRANSFERRED IN THE ABSENCE OF SUCH
REGISTRATION OR AN APPLICABLE EXEMPTION THEREFROM. EACH PURCHASER OF THIS SECURITY IS HEREBY NOTIFIED THAT THE SELLER OF THIS SECURITY MAY BE RELYING ON THE EXEMPTION FROM THE PROVISIONS OF SECTION 5 OF THE SECURITIES ACT PROVIDED BY RULE 144A
THEREUNDER. 
  
 THE HOLDER OF THIS SECURITY AGREES FOR THE BENEFIT
OF OSCIENT PHARMACEUTICALS CORPORATION THAT (A) PRIOR TO THE EXPIRATION OF THE HOLDING PERIOD APPLICABLE TO SALES OF THIS SECURITY UNDER RULE 144(K) UNDER THE SECURITIES ACT (OR ANY SUCCESSOR PROVISION), THIS SECURITY AND THE SHARES OF COMMON STOCK
ISSUABLE UPON CONVERSION HEREOF MAY BE OFFERED, RESOLD, PLEDGED OR OTHERWISE TRANSFERRED ONLY TO (I) OSCIENT PHARMACEUTICALS CORPORATION OR ANY SUBSIDIARY THEREOF, (II) TO A PERSON WHOM THE SELLER REASONABLY BELIEVES IS A QUALIFIED INSTITUTIONAL
BUYER (AS DEFINED IN RULE 144A UNDER THE SECURITIES ACT) IN A TRANSACTION MEETING THE REQUIREMENTS OF RULE 144A, (III) PURSUANT TO AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT PROVIDED BY RULE 144 THEREUNDER (IF AVAILABLE) OR (IV)
PURSUANT TO A REGISTRATION STATEMENT WHICH HAS BEEN DECLARED EFFECTIVE UNDER THE SECURITIES ACT, IN EACH CASE IN ACCORDANCE WITH ANY APPLICABLE SECURITIES LAWS OF ANY STATE OF THE UNITED STATES, AND (B) THE HOLDER WILL, AND EACH SUBSEQUENT HOLDER IS
REQUIRED TO, NOTIFY ANY PURCHASER OF THIS SECURITY OF THE RESALE RESTRICTIONS REFERRED TO IN CLAUSE (A) ABOVE. THIS LEGEND WILL BE REMOVED UPON THE EARLIER OF THE TRANSFER OF THIS SECURITY PURSUANT TO CLAUSE (A)(IV) ABOVE OR UPON ANY TRANSFER OF
THIS SECURITY UNDER RULE 144(K) UNDER THE SECURITIES ACT (OR ANY SUCCESSOR PROVISION). THE INDENTURE CONTAINS A PROVISION REQUIRING THE TRUSTEE TO REFUSE TO REGISTER THE TRANSFER OF THIS SECURITY IN VIOLATION OF THE FOREGOING RESTRICTION. IN
ADDITION, THE HOLDER HEREOF WILL NOT, DIRECTLY OR INDIRECTLY, ENGAGE IN ANY HEDGING TRANSACTIONS WITH REGARD TO THIS SECURITY OR THE COMMON STOCK ISSUABLE UPON THE CONVERSION HEREOF EXCEPT AS PERMITTED UNDER THE SECURITIES ACT (OR ANY SUCCESSOR
ACT). 
  

 [INCLUDE IF SECURITY IS A GLOBAL SECURITY — THIS SECURITY IS A GLOBAL SECURITY WITHIN THE
MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF A DEPOSITARY OR A NOMINEE THEREOF. THIS SECURITY MAY NOT BE EXCHANGED IN WHOLE OR IN PART FOR A SECURITY REGISTERED, AND NO TRANSFER OF THIS SECURITY IN WHOLE OR IN
PART MAY BE REGISTERED, IN THE NAME OF ANY PERSON OTHER THAN SUCH DEPOSITARY OR A NOMINEE THEREOF, EXCEPT IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE. 
  
 UNLESS THIS CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (“DTC”), A
NEW YORK CORPORATION, TO THE COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC
(AND ANY PAYMENT IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL IN AS MUCH AS THE REGISTERED
OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN.] 
  

 A-2 

 Oscient Pharmaceuticals Corporation 
  
 31⁄2% Senior Convertible Notes Due 2011 
  

					
	 No. [    ]
	  	CUSIP NO. 68812RAA3	  	U.S. $[            ]

  
 Oscient
Pharmaceuticals Corporation, a corporation duly organized and validly existing under the laws of the Commonwealth of Massachusetts (herein called the “Company”), which term includes any successor corporation under the Indenture
referred to on the reverse hereof), for value received hereby promises to pay to [    ], or registered assigns, the principal sum of [    ] United States Dollars ($ ) [INCLUDE IF SECURITY IS A GLOBAL
SECURITY — (which amount may from time to time be increased or decreased by adjustments made on the records of the Trustee, as custodian for the Depositary, in accordance with the rules and procedures of the Depositary)] on April 15, 2011
and to pay interest on said principal sum semi-annually on April 15 and October 15 of each year, commencing October 15, 2004 at the rate of 31⁄2% per annum to Holders of record on the immediately preceding April 1 and October 1, respectively.
Interest on this Security shall accrue from the most recent date to which interest has been paid, or if no interest has been paid, from May 10, 2004 until the Principal Amount is paid or duly made available for payment. Except as otherwise provided
in the Indenture, the interest payable on this Security pursuant to the Indenture on any April 15 or October 15 will be paid to the Person in whose name this Security (or one or more predecessor Securities) is registered at the close of business on
the Record Date, which shall be April 1 and October 1 (whether or not a Business Day) next preceding such April 15 or October 15, respectively. Payment of the principal of and interest accrued on this Security shall be made by check mailed to the
address of the Holder of this Security specified in the register of Securities, or, upon written application by a Holder of an aggregate Principal Amount of greater than U.S. $2 million to the Security Registrar setting forth wire instructions not
later than ten days prior to the relevant payment date, such Holder may receive payment by wire transfer in immediately available funds, in such lawful money of the United States of America as at the time of payment shall be legal tender for the
payment of public and private debts. 
  
 The Issue Date of this
Security is May [    ], 2004. 
  
 The
Holder of this Security is entitled to the benefits of the Pledge Agreement, dated as of May 10, 2004, by and among the Company, U.S. Bank National Association, as the trustee (the “Trustee”), and U.S. Bank National Association, as
securities intermediary for the Trustee and the Holders from time to time (the “Pledged Securities Intermediary”) and pursuant to which the Company has placed in the Pledge Account cash or Pledged Securities sufficient to provide for the
payment of the first six interest payments on the Securities. 
  
 Reference is made to the further provisions of this Security set forth on the reverse hereof, including, without limitation, provisions giving the Company the right to repurchase this Security commencing May 10, 2010, the right to convert
this Security into Common Stock of the Company and the right of the Holder of this Security to require the Company to repurchase this 

  

 A-3 

 
Security and upon certain events, in each case, on the terms and subject to the limitations referred to on the reverse hereof and as more fully specified in
the Indenture. Such further provisions shall for all purposes have the same effect as though fully set forth at this place. Capitalized terms used but not defined herein shall have such meanings as are ascribed to such terms in the Indenture.

  
 This Security shall be deemed to be a contract made under the
laws of the State of New York, and for all purposes shall be construed in accordance with and governed by the laws of said State. 
  
 This Security shall not be valid or become obligatory for any purpose until the certificate of authentication hereon shall have been manually signed by
the Trustee or a duly authorized authenticating agent under the Indenture. 
  
 IN WITNESS WHEREOF, the Company has caused this instrument to be duly executed. 
  

			
	OSCIENT PHARMACEUTICALS CORPORATION
		
	By:	 	 
	 Authorized Signatory

  

 A-4 

 EXHIBIT B 
  

FORM OF REVERSE OF SECURITY 
  
 This Security is one of a duly authorized issue of Securities of the Company, designated as its 31⁄2% Senior Convertible Notes Due 2011 (the
“Securities”), all issued or to be issued under and pursuant to an Indenture, dated as of May 10, 2004 (the “Indenture”), between the Company and U.S. Bank National Association (the “Trustee”), to
which Indenture and all indentures supplemental thereto reference is hereby made for a description of the rights, limitations of rights, obligations, duties and immunities thereunder of the Trustee, the Company and the Holders of the Securities.

  
 The indebtedness evidenced by the Securities is unsecured and
unsubordinated senior indebtedness of the Company and ranks equally with the Company’s other unsecured and unsubordinated senior indebtedness, except as provided in Paragraph 6 hereof. 
  
 Redemption at the Option of the Company. No sinking
fund is provided for the Securities. The Securities are redeemable as a whole, or from time to time in part, at any time commencing on May 10, 2010 at the option of the Company at a redemption price (the “Redemption Price”) equal to
100%, expressed as a percentage of the Principal Amount of Securities to be redeemed, together with accrued and unpaid interest and Liquidated Damages, if any, to, but excluding, the Redemption Date. 
  
 Repurchase by the Company at the Option of the Holder Upon
a Fundamental Change. Subject to the terms and conditions of the Indenture, the Company shall become obligated, at the option of the Holder, to repurchase the Securities if a Fundamental Change occurs at any time prior to the Stated Maturity at
100% of the Principal Amount plus accrued and unpaid interest and Liquidated Damages, if any, to, but excluding, the Fundamental Change Repurchase Date (the “Fundamental Change Repurchase Price”), which Fundamental Change Repurchase
Price will be paid in cash; provided that if a Fundamental Change results from a Change of Control Event, the Company may elect, subject to the satisfaction of certain conditions described in the Indenture, to pay all or a portion of the Fundamental
Change Repurchase Price in Common Stock or a combination of cash and Common Stock; and provided, further, that the “Fundamental Change Repurchase Price” shall include any Make-Whole Premium required by the terms of the Indenture.
The number of shares of Common Stock a Holder will receive will equal the quotient obtained by dividing (i) the portion of the Fundamental Change Repurchase Price to be paid in shares of Common Stock by (ii) 97% of the average Closing Price of the
shares of Common Stock for the five Trading Day period ending on the second Business Day immediately preceding the Fundamental Change Repurchase Date, subject to adjustment as described in the Indenture. Notwithstanding the foregoing, a Holder will
not have the right to require the Company to repurchase the Securities upon a Change of Control Event constituting a Fundamental Change if the Closing Price per share of the Company’s Common Stock for any five Trading Days within the period of
10 consecutive Trading Days ending immediately after the later of the Change of Control Event and the public announcement of the Change of Control Event equals or exceeds 110% of the Conversion Price of the Securities in effect on each of those five
Trading Days. 
  

 Withdrawal of Fundamental Change Repurchase Notice. Holders have the right to
withdraw, in whole or in part, any Fundamental Change Repurchase Notice, by delivering to the Paying Agent a written notice of withdrawal in accordance with the provisions of the Indenture. 
  
 Payment of Redemption Price and Fundamental Change
Repurchase Price. If cash (and/or Common Stock, if permitted under the Indenture) sufficient to pay the Redemption Price or Fundamental Change Repurchase Price as the case may be, of all Securities or portions thereof to be redeemed or
repurchased on a Redemption Date or on a Fundamental Change, as the case may be, is deposited with the Paying Agent on the Business Day following the Redemption Date or the Fundamental Change Repurchase Date, as the case may be, the Securities to be
redeemed or repurchased will cease to be outstanding and interest and Liquidated Damages, if any, will cease to accrue on such Securities (or portions thereof) immediately after such Redemption Date or Fundamental Change Repurchase Date, as the case
may be, and the Holder thereof shall have no other rights as such (other than the right to receive the Redemption Price or Fundamental Change Repurchase Price as the case may be) upon surrender of such Security. 
  
 Conversion. Subject to the terms and conditions of
the Indenture, a Holder may convert each of its Securities into shares of the Company’s common stock at an initial conversion rate of 150.5571 shares per $1,000 Principal Amount of Securities (the “Conversion Rate”), at any time prior
to the close of business on April 14, 2011. The Conversion Rate in effect at any given time is subject to adjustment. A Holder may convert fewer than all of such Holder’s Securities so long as the Securities converted are an integral multiple
of $1,000 principal amount. Holders will not receive any cash payment representing accrued and unpaid interest or Liquidated Damages, if any, upon conversion of a Security. Accrued and unpaid interest and Liquidated Damages, if any, will be deemed
paid in full rather than canceled, extinguished or forfeited; provided, that if this Security shall be surrendered for conversion during the period from close of business on any Record Date for the payment of interest through the close of business
on the Business Day next preceding the following Interest Payment Date, such Security (or portion thereof being converted) must be accompanied by an amount, in funds acceptable to the Company, equal to the interest payable on such Interest Payment
Date on the Principal Amount being converted; provided, however, that no such payment shall be required if there shall exist at the time of conversion a default in the payment of interest on the Securities. 
  
 Pledge Agreement. The Company has entered into the
Pledge Agreement and purchased and pledged to the Trustee for its benefit and the ratable benefit of the Holders of the Securities the Pledged Securities in an amount sufficient upon receipt of scheduled interest and principal payments on such
Pledged Securities to provide for the payment in full of the first six scheduled interest payments (up to and including the interest payments due on April 15, 2007), but no Liquidated Damages, if any, on the Notes when due. The Pledged Securities
will be pledged by the Company to the Trustee for its benefit and the ratable benefit of the Holders 

  

 B-2 

 
and will be held by the Trustee in the Pledged Account pending disbursement pursuant to the Pledge Agreement. 
  
 [INCLUDE IF SECURITY IS A GLOBAL SECURITY — In the event of a
deposit or withdrawal of an interest in this Security, including an exchange, transfer, repurchase or conversion of this Security in part only, the Trustee, as custodian of the Depositary, shall make an adjustment on its records to reflect such
deposit or withdrawal in accordance with the rules and procedures of the Depositary.] 
  
 [INCLUDE IF SECURITY IS A RESTRICTED SECURITY — Subject to certain limitations in the Indenture, at any time when the Company is not subject to Section 13 or 15(d) of the United States Securities Exchange
Act of 1934, as amended, upon the request of a Holder of a Restricted Security, the Company will promptly furnish or cause to be furnished Rule 144A Information (as defined below) to such Holder of Restricted Securities, or to a prospective
purchaser of any such security designated by any such Holder, to the extent required to permit compliance by any such Holder with Rule 144A under the Securities Act of 1933, as amended (the “Securities Act”). “Rule 144A
Information” shall be such information as is specified pursuant to Rule 144A(d)(4) under the Securities Act (or any successor provision thereto).] 
  
 If an Event of Default shall occur and be continuing, the Principal Amount plus accrued and unpaid interest and Liquidated Damages, if any, through such
date on all the Securities may be declared due and payable in the manner and with the effect provided in the Indenture. 
  
 The Indenture permits, with certain exceptions as therein provided, the amendment thereof and the modification of the rights and obligations of the
Company and the rights of the Holders of the Securities under the Indenture at any time by the Company and the Trustee with the consent of the Holders of not less than a majority in aggregate Principal Amount of the Outstanding Securities. The
Indenture also contains provisions permitting the Holders of specified percentages in aggregate Principal Amount of the Outstanding Securities, on behalf of the Holders of all the Securities, to waive compliance by the Company with certain
provisions of the Indenture and certain past defaults under the Indenture and their consequences. Any such consent or waiver by the Holder of any provision of or applicable to this Security shall be conclusive and binding upon such Holder and upon
all future Holders of this Security and of any Security issued upon the registration of transfer hereof or in exchange herefor or in lieu hereof, whether or not notation of such consent or waiver is made upon this Security. 
  
 As provided in and subject to the provisions of the Indenture, the Holder of
this Security shall not have the right to institute any proceeding with respect to the Indenture or for the appointment of a receiver or trustee or for any other remedy thereunder, unless such Holder shall have previously given the Trustee written
notice of a continuing Event of Default with respect to the Securities, the Holders of not less than 25% in aggregate Principal Amount of the Outstanding Securities shall have made written request to the Trustee to institute proceedings in respect
of such Event of Default as Trustee and offered the Trustee reasonable indemnity satisfactory to it, the Trustee shall not have received from the Holders of a majority in Principal Amount of Outstanding Securities a direction inconsistent with such
request, and the Trustee 

  

 B-3 

 
shall have failed to institute any such proceeding, for 60 days after receipt of such notice, request and offer of indemnity. The foregoing shall not apply
to any suit instituted by the Holder of this Security for the enforcement of any payment of said principal hereof or interest hereon on or after the respective due dates expressed herein or for the enforcement of any conversion right. 
  
 No reference herein to the Indenture and no provision of this Security or of
the Indenture shall alter or impair the obligation of the Company, which is absolute and unconditional, to pay the Principal Amount or Fundamental Change Repurchase Price of or interest and Liquidated Damages, if any, on, this Security at the times,
place and rate, and in the coin or currency, herein prescribed. 
  
 As provided in the Indenture and subject to certain limitations therein set forth, the transfer of this Security is registrable in the Security Register, upon surrender of this Security for registration of transfer at the office or agency
of the Company in The City of New York, duly endorsed by, or accompanied by a written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed by, the Holder hereof or his attorney duly authorized in
writing, and thereupon one or more new Securities, of authorized denominations and for the same aggregate Principal Amount, will be issued to the designated transferee or transferees. 
  
 The Securities are issuable only in registered form in denominations of $1,000 and any integral multiple of $1,000 above
that amount, as provided in the Indenture and subject to certain limitations therein set forth. Securities are exchangeable for a like aggregate Principal Amount of Securities of a different authorized denomination, as requested by the Holder
surrendering the same. 
  
 No service charge shall be made for any
such registration of transfer or exchange, but the Company may require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 
  
 Prior to due presentment of this Security for registration of transfer, the Company, the Trustee and any agent of the
Company or the Trustee may treat the Person in whose name this Security is registered as the owner hereof for all purposes, whether or not this Security be overdue, and neither the Company, the Trustee nor any such agent shall be affected by notice
to the contrary. 
  
 This Security shall be governed by and
construed in accordance with the laws of the State of New York. 
  
 All terms used in this Security that are defined in the Indenture shall have the meanings assigned to them in the Indenture. 
  

 B-4 

 ASSIGNMENT FORM 
  
 If you want to assign this Security, fill in the form below and have your signature guaranteed: 
  
 I or we assign and transfer this Security to: 
  

	
	 
	
	 
	
	 

 (Print or type name, address and zip code and social security or tax ID number of assignee) 
  
 and irrevocably appoint
                                        
                                         agent
to transfer this Security on the books of the Company. The agent may substitute another to act for him. 
  

					
			
	 Date:
                                
	 	 	 	 Signed:
                                        
                        

  
 (Sign exactly as your
name appears on the other side of this Security) 
  
 Signature
Guarantee:
                                        
                                     
  
 Note: Signatures must be guaranteed by an “eligible guarantor institution” meeting
the requirements of the Security Registrar, which requirements include membership or participation in the Security Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be determined
by the Security Registrar in addition to, or in substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934, as amended. 
  

 B-5 

 In connection with any transfer of this Security occurring prior to the date which is the earlier of (i)
the date of the declaration by the Commission of the effectiveness of a registration statement under the Securities Act, as amended (the “Securities Act”), covering resales of this Security (which effectiveness shall not have been
suspended or terminated at the date of the transfer) and (ii) the second anniversary of the Issue Date set forth on the face of this Security, the undersigned confirms that it has not utilized any general solicitation or general advertising in
connection with the transfer and that this Security is being transferred: 
  
 [Check One] 
  

						
			
	(1)	  	 ̈	 	  	to the Company or a subsidiary thereof; or
			
	(2)	  	 ̈	 	  	to a “Qualified Institutional Buyer” pursuant to and in compliance with Rule 144A under the Securities Act; or
			
	(3)	  	 ̈	 	  	pursuant to the exemption from registration provided by Rule 144 under the Securities Act.

  
 Unless one of the above boxes is
checked, the Trustee will refuse to register any of the Securities evidenced by this certificate in the name of any Person other than the registered Holder thereof, provided that if box (3) is checked, the Company may require, prior to registering
any such transfer of the Securities, in its sole discretion, such legal opinions, certifications and other information as the Company may reasonably request to confirm that such transfer is being made pursuant to an exemption from, or in a
transaction not subject to, the registration requirements of the Securities Act. 
  
 If none of the foregoing boxes is checked, the Trustee or Security Registrar shall not be obligated to register this Security in the name of any Person other than the Holder hereof unless and until the conditions to
any such transfer of registration set forth herein and in Section 3.09 of the Indenture shall have been satisfied. 
  

					
			
	 Date:                                     
   
	 	 	 	 Signed:
                                        
                    

	 	 	 	 	 (Sign exactly as your name appears on the other side of this Security)

  
 Signature
Guarantee:                                      
                                        
                                
  
 Note: Signatures must be guaranteed by an “eligible guarantor institution” meeting the requirements of the Security Registrar,
which requirements include membership or participation in the Security Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be determined by the Security Registrar in addition to, or in
substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934, as amended. 
  

 B-6 

 TO BE COMPLETED BY PURCHASER IF (2) ABOVE IS CHECKED 
  
 The undersigned represents and warrants that it is purchasing this Security
for its own account or an account with respect to which it exercises sole investment discretion and that it and any such account is a “qualified institutional buyer” within the meaning of Rule 144A under the Securities Act and is aware
that the sale to it is being made in reliance on Rule 144A and acknowledges that it has received such information regarding the Company as the undersigned has requested pursuant to Rule 144A or has determined not to request such information and that
it is aware that the transferor is relying upon the undersigned’s foregoing representations in order to claim the exemption from registration provided by Rule 144A. 
  

					
			
	 Date:                                     
   
	 	 	 	 Signed:
                                        
                    

  
 NOTICE: To be executed
by an executive officer. 
  

 B-7 

 CONVERSION NOTICE 
  

If you want to convert this Security into Common Stock of the Company, check the box: 
  
 To convert only part of this Security, state the Principal Amount to be converted (which must be $1,000 or an integral
multiple of $1,000): 
  
 $                                      
                   
  
 If you want the stock certificate made out in another person’s name, fill in the form below: 
  

	
	 
	(Insert other person’s social security or tax ID no.)
	
	 
	
	 
	
	 
	(Print or type other person’s name, address and zip code)

  

					
			
	 Date:
                                        
    
	 	 Signed:
	 	  
	 	 	 	 	 

  
 (Sign exactly as your
name appears on the other side of this Security) 
  
 Signature
Guarantee:                                      
                               
  
 Note: Signatures must be guaranteed by an “eligible guarantor institution” meeting the requirements of the Security Registrar,
which requirements include membership or participation in the Security Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be determined by the Security Registrar in addition to, or in
substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934, as amended. 
  

 B-8 

 EXHIBIT C 
  

FORM OF TRUSTEE’S CERTIFICATE OF AUTHENTICATION 
  
 U.S. Bank National Association, as Trustee, certifies that this is one of the Securities referred to in the within-mentioned Indenture. 
  

									
	 Dated:
                            
	 	 	 	 U.S. BANK NATIONAL ASSOCIATION, as Trustee

					
	 	 	 	 	 	 	By:	 	 
	 	 	 	 	 	 	 Authorized Signatory

  

 EXHIBIT D 
  

FORM OF FUNDAMENTAL CHANGE REPURCHASE NOTICE 
  
                     ,
20         
  
 ________________________________ 
  
 ________________________________

  
 ________________________________ 
  
 ________________________________ 
  
 Attention: [Institutional Trust Services] 
  

	 	Re:	Oscient Pharmaceuticals Corporation (the “Company”) 

 31⁄2% Senior Convertible Notes Due 2011 
  
 This is a Fundamental Change Repurchase Notice as defined in Section 11.08 of the Indenture dated as of May 10, 2004 (the “Indenture”) between the Company and U.S. Bank National Association, as Trustee. Terms used but not defined
herein shall have the meanings ascribed to them in the Indenture. 
  
 Certificate
No(s). of Securities: ________________________ 
  
 I intend to
deliver the following aggregate Principal Amount of Securities for purchase by the Company pursuant to Section 11.08 of the Indenture (in multiples of $1,000): 
  

$_____________________________________ 
  
 I hereby agree that the Securities will be purchased as of the Fundamental Change Repurchase Date pursuant to the terms and conditions thereof and of the
Indenture. 
  
 Signed:        ____________________________

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