Document:

Exhibit 10.1

 

AMENDMENT AGREEMENT

 

This Amendment Agreement
(the "Agreement") dated as of January 19, 2017, is by and between Great Basin Scientific, Inc., a Delaware corporation
with offices located at 420 E. South Temple, Suite 520, Salt Lake City, Utah 84111 (the "Company"), and the Holder
whose signature is set forth below (the "Holder"). All terms used and not defined herein are used as defined in
the Securities Purchase Agreement and the Notes (each as defined below), as applicable.

 

WHEREAS:

 

A. The
Company, the Holder and other Buyers executed and delivered a Securities Purchase Agreement (the "Securities Purchase Agreement")
dated as of June 29, 2016 in reliance upon the exemption from securities registration afforded by Section 4(a)(2) of the 1933 Act,
and Rule 506(b) of Regulation D as promulgated by the SEC under the 1933 Act.

 

B. The
Company authorized the issuance of senior secured convertible notes of the Company (as amended prior to the date hereof, the "Notes"),
in the aggregate original principal amount of $75,000,000 which Notes are convertible into shares of Common Stock, in accordance
with the terms of the Notes.

 

C. In
compliance with Section 19 of the Notes, the Company and the Holder, which alone represents the Required Holders (as defined in
each of the Notes), desire to amend each of the Notes as set forth herein, which amendments shall be binding on the holders of
all Notes outstanding as of the execution and delivery of this Agreement by the Company and the Holder, (such time, the "Effective
Time").

 

NOW, THEREFORE,
in consideration of the premises and the mutual covenants contained herein and for other good and valuable consideration, the receipt
and sufficiency of which are hereby acknowledged, the parties hereto, intending to be legally bound, hereby agree as follows:

 

1. NO CHANGE TO
TERMS EXCEPT AS SET FORTH. Except as explicitly set forth in this Agreement, all terms of the Securities Purchase Agreement,
Notes, Warrants, the Security Documents and other Transaction Documents are, and shall continue to be, in full force and effect
and are hereby ratified and confirmed in all respects. Except as explicitly set forth herein, the Holder reserves all of its rights,
remedies, powers, and privileges. All references herein and in the Securities Purchase Agreement, Notes, Warrants, the Security
Documents and other Transaction Documents to the Notes shall mean on and after the Effective Time, respectively, the Securities
Purchase Agreement, Notes, Warrants, the Security Documents and such other Transaction Documents, each as amended by this Agreement.

 

2. CHANGES TO THE
NOTES.

 

a.Section 8
of the Notes is hereby amended by replacing it in its entirety with "Intentionally Omitted" and any reference to any
defined terms appearing elsewhere in the Notes that relate solely to Section 8 and that are not otherwise used in the Notes, is
hereby deleted. The Pre-Installment Conversion Shares delivered by the Company to any holder of Notes with respect to the Installment
Date that was, prior to the Effective Time, scheduled to occur on January 30, 2017, shall immediately reduce the principal amount
of the Notes outstanding by $0.044 for each Pre-Installment Conversion Share so delivered.

 

     

     

    

 

b.Section 3(b)(ii)
of the Notes is hereby amended by replacing it in its entirety with the following:

 

"(ii)"Conversion
Price" means, as of any Conversion Date or other date of determination, the lowest of (x) $2.00 per share, subject to
adjustment as provided herein, (y) 85% of the lower of (I) the lowest Weighted Average Price
of the Common Stock and (II) the lowest Closing Bid Price of the Common Stock, in each case, during the five (5) consecutive Trading
Day period ending on, and including, the Trading Day on which the Holder delivers a Conversion Notice to the Company (such trading
prices to be appropriately adjusted for any share dividend, share split, share combination, reclassification or similar transaction
during such five (5) consecutive Trading Day period) and (z) 85% of the Weighted Average Price of the Common Stock during the period
beginning at 9:30:01 a.m., New York time (or such other time as the Principal Market publicly announces the official opening
of trading), and ending at 1:00:00 p.m., New York time, on the delivery date of the applicable Conversion Notice."

 

3. ACKNOWLEDGEMENT.
The Company hereby acknowledges and agrees that as of the date hereof a Control Account Holder Release Event has occurred and is
continuing.

 

4. RULE 144.
For purposes of Rule 144 of the 1933 Act, the Company acknowledges and agrees that the holding period of the Notes, as amended
by this Agreement, commenced on July 1, 2016 and the Company agrees not to take a position contrary thereto or inconsistent therewith.

 

5. DISCLOSURE OF
TRANSACTIONS AND OTHER MATERIAL INFORMATION. The Company shall, on or before 8:30 a.m., New York City Time, January 20,
2017, file a Current Report on Form 8-K disclosing all material terms of the transactions contemplated hereby attaching the form
of this Agreement as exhibit to such filing (including all attachments), the "8-K Filing"). From
and after the filing of the 8-K Filing, the Holder shall not be in possession of any material, nonpublic information received
from the Company, any of its Subsidiaries or any of its respective officers, directors, employees, agents or affiliates, that
is not disclosed in the 8-K Filing. In addition, effective upon the filing of the 8-K Filing, the Company acknowledges and agrees
that any and all confidentiality or similar obligations under any agreement, whether written or oral, between the Company, any
of its Subsidiaries or any of their respective officers, directors, affiliates, employees or agents, on the one hand, and the
Holder or any of its affiliates, on the other hand, shall terminate and be of no further force or effect. The Company shall not,
and shall cause each of its Subsidiaries and each of their respective officers, directors, employees, agents and affiliates, not
to, provide the Holder with any material, nonpublic information regarding the Company or any of its Subsidiaries from and after
the date hereof without the express prior written consent of the Holder. To the extent that the Company delivers any material,
non-public information to the Holder without such Holder's express prior written consent, the Company hereby covenants and agrees
that the Holder shall not have any duty of confidentiality to the Company, any of its Subsidiaries or any of their respective
officers, directors, employees, affiliates or agents with respect to, or a duty to the Company, any of its Subsidiaries or any
of their respective officers, directors, employees, affiliates or agents not to trade on the basis of, such material, non-public
information. The Company understands and confirms that the undersigned and its affiliates will rely on the foregoing representations
in effecting transactions in securities of the Company. The Company shall not disclose the name of the Holder in any filing, announcement,
release or otherwise, unless such disclosure is required by law or regulation.

 

     

     

    

 

6. The
Company shall reimburse the Holder for its legal fees and expenses in connection with the preparation and negotiation of this Agreement
and transactions contemplated thereby, by paying on or prior to the fifth (5th) Business Day immediately following the
date hereof any such amount to Schulte Roth & Zabel LLP (the "Counsel Expense") by wire transfer of immediately
available funds in accordance with the written instructions of Schulte Roth & Zabel LLP delivered to the Company. The Counsel
Expense shall be paid by the Company whether or not the transactions contemplated by this Agreement are consummated. Except as
otherwise set forth above, each party shall pay the fees and expenses of its advisers, counsel, accountants and other experts,
if any, and all other expenses incurred by such party incident to the negotiation, preparation, execution, delivery and performance
of this Agreement. The Company shall pay all stamp and other taxes and duties levied in connection with the transactions contemplated
hereby, if any.

 

7. MISCELLANEOUS.
All provisions of Article 9 of the Securities Purchase Agreement are incorporated herein by reference mutatis mutandis;
provided, however, that any amendment of this Agreement shall require the consent of the undersigned.

 

[The remainder of this
page is intentionally left blank]

 

     

     

    

 

IN WITNESS WHEREOF,
the Holder and the Company have caused their respective signature page to this Agreement to be duly executed as of the date first
written above.

 

	 	COMPANY:
	 	 	 
	 	Great Basin Scientific, Inc.
	 	 	 
	 	By:	 
	 	 	Name:
	 	 	Title:

 

     

     

    

 

IN WITNESS WHEREOF,
each Holder and the Company have caused their respective signature page to this Agreement to be duly executed as of the date first
written above.

 

	 	HOLDER:
	 	 	 
	 	[     ]
	 	 	 
	 	By: 
	 	 	 
	 	By:	 
	 	 	Name: 
	 	 	Title:EXHIBIT 10.1

 

EIGHTH
AMENDMENT TO AMENDED AND RESTATED CREDIT AGREEMENT

 

This EIGHTH AMENDMENT
TO AMENDED AND RESTATED CREDIT AGREEMENT (this “Amendment”) is made and entered into as of January 13, 2017
(the “Amendment Closing Date”) by and among Bacterin
International, Inc., a Nevada corporation (the “Borrower”), ROS
acquisition offshore lp, a Cayman Islands Exempted Limited Partnership (“ROS”), OrbiMed Royalty Opportunities
II, LP, a Delaware limited partnership (“Royalty Opportunities”), and, in their capacity as Guarantors under
the Credit Agreement (as defined below), XTANT MEDICAL HOLDINGS, INC., a Delaware corporation (“Holdings”),
X-SPINE SYSTEMS, INC., an Ohio corporation (“X-Spine”) and XTANT MEDICAL, INC., a Delaware corporation
(“Xtant” and, along with Holdings and X-Spine, collectively, the “Guarantors”).

 

WHEREAS, the Borrower,
ROS and Royalty Opportunities are party to that certain Amended and Restated Credit Agreement, dated as of July 27, 2015, as amended
by that certain First Amendment to Amended and Restated Credit Agreement, dated as of March 31, 2016, that certain Second Amendment
to Amended and Restated Credit Agreement, dated as of May 25, 2016, that certain Third Amendment to Amended and Restated Credit
Agreement, dated as of June 30, 2016, that certain Fourth Amendment to Amended and Restated Credit Agreement, dated as of July
29, 2016, that certain Fifth Amendment to the Amended and Restated Credit Agreement, dated as of August 12, 2016, that certain
Sixth Amendment to the Amended and Restated Credit Agreement, dated as of September 27, 2016, and that certain Seventh Amendment
to the Amended and Restated Credit Agreement, dated as of December 31, 2016 (the “Credit Agreement”), pursuant
to which (i) ROS and Royalty Opportunities, as Lenders under the Credit Agreement, have extended credit to the Borrower on the
terms set forth therein and (ii) each Lender has appointed ROS as the administrative agent (the “Administrative Agent”)
for the Lenders;

 

WHEREAS, the Guarantors
and the Administrative Agent entered into an Amended and Restated Guarantee, dated as of July 31, 2015 and supplemented on September
11, 2015, pursuant to which the Guarantors have agreed to guarantee the Obligations of the Borrower under the Credit Agreement;

 

WHEREAS, pursuant
to Section 11.1 of the Credit Agreement, the Credit Agreement may be amended by an instrument in writing signed by each of the
Borrower and the Administrative Agent (acting on behalf of the Lenders);

 

WHEREAS, the Borrower
and the Lenders desire to amend certain provisions of the Credit Agreement as provided in this Amendment.

 

NOW, THEREFORE,
in consideration of the mutual agreements herein contained, and for other good and valuable consideration, the receipt and sufficiency
of which are hereby acknowledged, the parties hereto agree as follows:

 

     

     

    

 

1.          Definitions;
Loan Document. Capitalized terms used herein without definition shall have the meanings assigned to such terms in the Credit
Agreement. This Amendment shall constitute a Loan Document for all purposes of the Credit Agreement and the other Loan Documents.

  

2.          Amendments
to Section 3.6. Section 3.6 of the Credit Agreement is hereby amended by deleting the last sentence from such Section 8.4(b)
in its entirety and inserting the following as the last sentence thereof:

 

“Notwithstanding the foregoing,
interest accrued on the Loans for the Fiscal Quarter ended on December 31, 2016 and otherwise required to be paid in cash on January
2, 2017, shall instead be required to be paid in cash on January 31, 2017, plus interest accrued on such interest from January
2, 2017 to the date of payment thereof at a rate equal to the Applicable Margin plus the higher of (i) the LIBO Rate for the Fiscal
Quarter ended on December 31, 2016, and (ii) 1.00%.”

 

3.          Conditions
to Effectiveness of Amendment. This Amendment shall become effective upon receipt by the Borrower, the Administrative Agent,
the Lenders and the Guarantors of a counterpart signature of the others to this Amendment duly executed and delivered by each of
the Borrower, the Lenders, the Administrative Agent and the Guarantors.

 

4.          Expenses.
The Borrower agrees to pay on demand all expenses of the Administrative Agent (including, without limitation, the fees and out-of-pocket
expenses of Covington & Burling LLP, counsel to the Administrative Agent) incurred in connection with the Administrative Agent’s
review, consideration and evaluation of this Amendment, including the rights and remedies available to it in connection therewith,
and the negotiation, preparation, execution and delivery of this Amendment.

 

5.          Representations
and Warranties. The Borrower and the Guarantors represent and warrant to each Lender as follows:

 

(a)        After
giving effect to this Amendment, the representations and warranties of the Borrower and the Guarantors contained in the Credit
Agreement or any other Loan Document shall, (i) with respect to representations and warranties that contain a materiality qualification,
be true and correct in all respects on and as of the date hereof, and (ii) with respect to representations and warranties that
do not contain a materiality qualification, be true and correct in all material respects on and as of the date hereof, and except
that the representations and warranties limited by their terms to a specific date shall be true and correct as of such date.

 

(b)        After
giving effect to this Amendment, no Default or Event of Default under the Credit Agreement will occur or be continuing.

 

6.          No
Implied Amendment or Waiver. Except as expressly set forth in this Amendment, this Amendment shall not, by implication
or otherwise, limit, impair, constitute a waiver of or otherwise affect any rights or remedies of the Administrative Agent or the
Lenders under the Credit Agreement or the other Loan Documents, or alter, modify, amend or in any way affect any of the terms,
obligations or covenants contained in the Credit Agreement or the other Loan Documents, all of which shall continue in full force
and effect. Nothing in this Amendment shall be construed to imply any willingness on the part of the Administrative Agent or the
Lenders to agree to or grant any similar or future amendment, consent or waiver of any of the terms and conditions of the Credit
Agreement or the other Loan Documents.

 

    	 	- 2 -	 

     

    

 

7.          Waiver
and Release. TO INDUCE THE ADMINISTRATIVE AGENT, ACTING ON BEHALF OF THE LENDERS, TO AGREE TO THE TERMS OF THIS AMENDMENT,
THE BORROWER, THE GUARANTORS AND THEIR AFFILIATES (COLLECTIVELY, THE RELEASING PARTIES”) REPRESENT AND WARRANT THAT
AS OF THE DATE HEREOF THERE ARE NO CLAIMS OR OFFSETS AGAINST OR RIGHTS OF RECOUPMENT WITH RESPECT TO OR DEFENSES OR COUNTERCLAIMS
TO THEIR OBLIGATIONS UNDER THE LOAN DOCUMENTS AND IN ACCORDANCE THEREWITH THEY:

 

(a)        WAIVE
ANY AND ALL SUCH CLAIMS, OFFSETS, RIGHTS OF RECOUPMENT, DEFENSES OR COUNTERCLAIMS, WHETHER KNOWN OR UNKNOWN, ARISING PRIOR TO THE
DATE HEREOF; AND

 

(b)        FOREVER
RELEASE, RELIEVE, AND DISCHARGE THE ADMINISTRATIVE AGENT, THE LENDERS, THEIR OFFICERS, DIRECTORS, SHAREHOLDERS, MEMBERS, PREDECESSORS,
SUCCESSORS, ASSIGNS, ATTORNEYS, ACCOUNTANTS, AGENTS, EMPLOYEES, AND REPRESENTATIVES (COLLECTIVELY, THE "RELEASED PARTIES"),
AND EACH OF THEM, FROM ANY AND ALL CLAIMS, LIABILITIES, DEMANDS, CAUSES OF ACTION, DEBTS, OBLIGATIONS, PROMISES, ACTS, AGREEMENTS,
AND DAMAGES, OF WHATEVER KIND OR NATURE, WHETHER KNOWN OR UNKNOWN, SUSPECTED OR UNSUSPECTED, CONTINGENT OR FIXED, LIQUIDATED OR
UNLIQUIDATED, MATURED OR UNMATURED, WHETHER AT LAW OR IN EQUITY, WHICH THE RELEASING PARTIES EVER HAD, NOW HAVE, OR MAY, SHALL,
OR CAN HEREAFTER HAVE, DIRECTLY OR INDIRECTLY ARISING OUT OF OR IN ANY WAY BASED UPON, CONNECTED WITH, OR RELATED TO MATTERS, THINGS,
ACTS, CONDUCT, AND/OR OMISSIONS AT ANY TIME FROM THE BEGINNING OF THE WORLD THROUGH AND INCLUDING THE DATE HEREOF, INCLUDING WITHOUT
LIMITATION ANY AND ALL CLAIMS AGAINST THE RELEASED PARTIES ARISING UNDER OR RELATED TO THE LOAN DOCUMENTS OR THE TRANSACTIONS CONTEMPLATED
THEREBY.

 

(c)        IN
CONNECTION WITH THE RELEASE CONTAINED HEREIN, THE RELEASING PARTIES ACKNOWLEDGE THAT THEY ARE AWARE THAT THEY MAY HEREAFTER DISCOVER
CLAIMS PRESENTLY UNKNOWN OR UNSUSPECTED, OR FACTS IN ADDITION TO OR DIFFERENT FROM THOSE WHICH THEY KNOW OR BELIEVE TO BE TRUE,
WITH RESPECT TO THE MATTERS RELEASED HEREIN. NEVERTHELESS, IT IS THE INTENTION OF THE RELEASING PARTIES, THROUGH THIS AGREEMENT
AND WITH ADVICE OF COUNSEL, FULLY, FINALLY, AND FOREVER TO RELEASE ALL SUCH MATTERS, AND ALL CLAIMS RELATED THERETO, WHICH DO NOW
EXIST, OR HERETOFORE HAVE EXISTED. IN FURTHERANCE OF SUCH INTENTION, THE RELEASES HEREIN GIVEN SHALL BE AND REMAIN IN EFFECT AS
A FULL AND COMPLETE RELEASE OR WITHDRAWAL OF SUCH MATTERS NOTWITHSTANDING THE DISCOVERY OR EXISTENCE OF ANY SUCH ADDITIONAL OR
DIFFERENT CLAIMS OR FACTS RELATED THERETO.

 

    	 	- 3 -	 

     

    

 

(d)        THE
RELEASING PARTIES COVENANT AND AGREE NOT TO BRING ANY CLAIM, ACTION, SUIT, OR PROCEEDING AGAINST THE RELEASED PARTIES, DIRECTLY
OR INDIRECTLY, REGARDING OR RELATED IN ANY MANNER TO THE MATTERS RELEASED HEREBY, AND FURTHER COVENANT AND AGREE THAT THIS AGREEMENT
IS A BAR TO ANY SUCH CLAIM, ACTION, SUIT, OR PROCEEDING.

 

(e)        THE
RELEASING PARTIES REPRESENT AND WARRANT TO THE RELEASED PARTIES THAT THEY HAVE NOT HERETOFORE ASSIGNED OR TRANSFERRED, OR PUPORTED
TO ASSIGN OR TRANSFER, TO ANY PERSON OR ENTITY ANY CLAIMS OR OTHER MATTERS HEREIN RELEASED.

 

8.          Counterparts;
Governing Law. This Amendment may be executed in any number of counterparts and by different parties hereto on separate
counterparts, each of such when so executed and delivered shall be an original, but all of such counterparts shall together constitute
but one and the same agreement. Delivery of an executed counterpart of a signature page of this Amendment by fax transmission or
other electronic mail transmission (e.g., “pdf” or “tif”) shall be effective as delivery of a manually
executed counterpart of this Amendment. THIS AMENDMENT SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE INTERNAL LAWS
OF THE STATE OF NEW YORK (INCLUDING FOR SUCH PURPOSE SECTIONS 5-1401 AND 5-1402 OF THE GENERAL OBLIGATIONS LAW OF THE STATE OF
NEW YORK).

 

[Remainder
of Page Intentionally Left Blank]

 

    	 	- 4 -	 

     

    

 

IN WITNESS WHEREOF, the parties
hereto have caused this Amendment to be executed by their respective officers thereunto duly authorized as of the day and year
first above written.

 

	 	
        BACTERIN INTERNATIONAL, INC.,

        as the Borrower

	 	 
	 	By: 	/s/ John Gandolfo
	 	Name:  John Gandolfo
	 	Title:    CFO
	 	 
	 	
        XTANT MEDICAL HOLDINGS, INC.,

        (fka: Bacterin International Holdings, Inc.)

        as a Guarantor

	 	 
	 	By: 	/s/ John Gandolfo
	 	Name:  John Gandolfo
	 	Title:    CFO
	 	 
	 	
        X-SPINE SYSTEMS, INC.,

        as a Guarantor

	 	 
	 	By: 	/s/ John Gandolfo
	 	Name:  John Gandolfo
	 	Title:    CFO
	 	 
	 	
        XTANT MEDICAL, INC.,

        as a Guarantor

	 	 
	 	By:   	/s/ John Gandolfo
	 	Name:  John Gandolfo
	 	Title:    CFO

 

Signature Page to Eighth Amendment to
A&R Credit Agreement

 

     

     

    

 

	 	ROS Acquisition Offshore LP,

as a Lender and as the Administrative Agent
	 	 
	 	By OrbiMed Advisors LLC, solely in its 
	 	capacity as Investment Manager
	 	 
	 	By:	/s/ W. Carter Neild
	 	Name:  W. Carter Neild
	 	Title:    Member
	 	 
	 	ORBIMED ROYALTY OPPORTUNITIES II, LP,

as a Lender
	 	 
	 	By OrbiMed ROF II LLC,
	 	
        Its General Partner

         

	 	By OrbiMed Advisors LLC,
	 	its Managing Member
	 	 
	 	By: 	/s/ W. Carter Neild
	 	Name:  W. Carter Neild
	 	Title:    Member

 

Signature Page to Eighth Amendment to
A&R Credit Agreement

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