Document:

EX-10.5

 Exhibit 10.5 

SECOND AMENDMENT TO LEASE 

This Second Amendment to Lease (“Second Amendment”) is made as of March 24, 2015, by and between ARE-MA REGION NO.
48, LLC, a Delaware limited liability company (“Landlord”), and ARIAD Pharmaceuticals, Inc., a Delaware corporation (“Tenant”). 

RECITALS 
 A.
Landlord and Tenant have entered into that certain Lease Agreement dated as of January 4, 2013, as amended (i) by a First Amendment (“First Amendment”) to Lease dated as of September 16, 2013, and (ii) by a
letter dated as of October 17, 2013 (as so amended, the “Lease”), wherein Landlord leased to Tenant certain premises (“Premises”) located at 75-125 Binney Street, Cambridge, Massachusetts, more
particularly described in the Lease. 
 B. Landlord and Tenant desire to amend the Lease as hereinafter provided. 

C. Capitalized terms used and not otherwise defined herein shall have the meanings ascribed to them in the Lease. 

AGREEMENT 
 Now,
therefore, the parties hereto agree that the Lease is amended as follows: 
  

	1.	Target Commencement Date. The Basic Lease Provisions are hereby amended by changing the Target Commencement Date from February 20, 2015 to March 24, 2015. 

 

	2.	Commencement Date. Section 2 of the Lease is hereby amended as follows: 

  

	 	(a)	The first sentence of Section 2(b) is hereby deleted and replaced with the following: 

“The “Commencement Date” is agreed to be March 24, 2015. Notwithstanding the foregoing, Tenant’s obligation to
pay Rent hereunder shall be abated on a day for day basis for any period of Landlord Delay. The term “Landlord Delay” shall mean any actual net delay in Tenant’s completion of the Tenant Improvements caused by Landlord, all determined
and subject to the same conditions and limitations, mutatis mutandis, as applicable with respect to a Tenant Delay as provided in Section 4.2 of the Work Letter. 
  

	 	(b)	Section 2(b) is further amended by deleting the last sentence thereof. 

  

	 	(c)	Section 2(c) is hereby deleted from the Lease; all references thereto in the Lease are also deleted 

  

	3.	Base Rent Adjustments. Section 4(a) of the Lease shall be amended by deleting the same and substituting therefor the following: 

 

	 	“(a)	Base Rent Adjustments.  

  

	 	(i)	Base Rent shall be increased on each Adjustment Date by multiplying the Base Rent payable immediately before such Adjustment Date by the Base Rent Adjustment Percentage and adding the resulting amount to the Base Rent
payable immediately before such Adjustment Date. 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

  
 1 

	 	(ii)	Tenant shall also pay as part of Base Rent from and after the Commencement Date Additional TI Base Rent in an amount calculated in accordance with the provisions of Section 6.3 of the Work Letter. Any such
Additional TI Base Rent shall not be subject to adjustment by the Base Rent Adjustment Percentage. 

  

	 	(iii)	Base Rent, as so adjusted, shall thereafter be due as provided herein. Base Rent adjustments for any fractional calendar month shall be prorated.” 

 

	4.	Expansion Space. The term “Expansion Space” was defined in the First Amendment as approximately 135,988 rentable square feet in specified locations in the 75 Binney Building. For all purposes of
this Lease, from and after the date hereof, the term “Expansion Space” shall mean 135,988 undesignated rentable square feet in either or a combination of both the 125 Binney Building and the 75 Binney Building, without reference to any
specific space in either the 125 Binney Building or the 75 Binney Building. 

  

	5.	Utilities. Section 11(a) of the Lease is hereby amended by adding at the end thereof the following: 

“For avoidance of doubt, from and after the Commencement Date, except during and to the extent of any active construction of any Tenant
Improvements in the Premises pursuant to the Work Letter, all costs of power and other utilities used by Tenant constitute an Operating Expense under this Lease, and, accordingly, shall not be a TI Cost and shall not be paid from the TI
Allowance.” 
  

	6.	Work Letter; TI Allowances for Expansion Space. Exhibit C to the Lease is hereby deleted and the Amended and Restated Work Letter attached hereto as Exhibit C is substituted therefor.
The provisions of Section 4 of the First Amendment are hereby deleted, it being agreed that the provisions of the Amended and Restated Work Letter shall supersede the provisions thereof. 

 

	7.	Exhibit G (Adjustment Calculations for Unused TI Allowance for Expansion Space and ROFR Space). Exhibit G to the Lease is hereby deleted. 

 

	8.	Deletion of First Amendment Provisions. Section 2(b) and Section 5 of the First Amendment are hereby deleted from the Lease. The following is hereby substituted for
Section 5 of the First Amendment: 

 “5. Rent for Expansion Space and New Atrium Area.
From and after the Commencement Date, Base Rent, Additional TI Base Rent (as defined in Section 6.3 of the Work Letter), Administration Rent, and Additional Rent shall 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

  
 2 

 
be payable with respect to the Expansion Space and the New Atrium Area in accordance with the terms of the Lease. Notwithstanding the foregoing: (a) Base Rent and Administration Rent (but
not Additional TI Base Rent, which shall be payable from and after the Commencement Date to the extent due in accordance with the provisions of Section 6.3 of the Work Letter) payable in accordance with the Basic Lease Provisions and the
provisions of Section 3 and Section 4 of the Lease shall be waived with respect to the Expansion Space for the 15-month period from and after the Commencement Date; and (b) Tenant’s Share of Operating Expenses for
the Expansion Space payable in accordance with Section 5 of the Lease shall be waived until the earlier to occur of: (i) the expiration of the 24-month period from and after the Commencement Date; or (ii) the date upon which
Tenant or any permitted subtenant occupies all or a portion of the Expansion Premises for the Permitted Uses (pro rated for such portion of the Expansion Premises as is occupied by Tenant or such subtenant). 

 

	9.	Miscellaneous. 

  

	 	(a)	This Second Amendment (together with the Original Lease and the First Amendment, as each is amended hereby) constitutes the entire agreement between the parties with respect to the subject matter hereof and supersedes
all prior and contemporaneous oral and written agreements and discussions. This Second Amendment may be amended only by an agreement in writing, signed by the parties hereto. 

 

	 	(b)	This Second Amendment is binding upon and shall inure to the benefit of the parties hereto and their respective permitted successors in interest. 

 

	 	(c)	This Second Amendment may be executed in any number of counterparts, each of which shall be deemed an original, but all of which when taken together shall constitute one and the same instrument. 

 

	 	(d)	Landlord and Tenant each represents and warrants that it has not dealt with any broker, agent or other person (collectively “Broker”) in connection with this Second Amendment. Landlord and Tenant each
hereby agree to indemnify and hold the other harmless from and against any claims by any Broker claiming a commission or other form of compensation by virtue of having dealt with Tenant or Landlord, as applicable, with regard to this Second
Amendment. 

  

	 	(e)	As amended and/or modified by this Second Amendment, the Lease is hereby ratified and confirmed, and Landlord and Tenant each warrant and represent to each other that to the best of their respective knowledge and belief
as of the date of this Second Amendment, neither party is in default under the Lease. 

  

	 	(f)	All other terms of the Lease shall remain in full force and effect, unaltered and unchanged by this Second Amendment. 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

  
 3 

	 	(g)	In the event of any conflict between the provisions of this Second Amendment and the provisions of the Lease, the provisions of this Second Amendment shall prevail. Whether or not specifically amended by this Second
Amendment, all of the terms and provisions of the Lease are hereby amended to the extent necessary to give effect to the purpose and intent of this Second Amendment. 

(Signatures on Next Page) 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

  
 4 

 IN WITNESS WHEREOF, the parties hereto have executed this Second Amendment as of the day and year
first above written. 
  

							
	TENANT
	
	 ARIAD Pharmaceuticals, Inc.
 a
Delaware corporation

		
	By:		 /s/ Edward M. Fitzgerald

	Name:		 Edward M. Fitzgerald

	Title:		 Executive Vice President, CFO

			Hereunto Duly Authorized
	
	LANDLORD
	
	ARE-MA REGION NO. 48, LLC, a Delaware limited liability company
		
	By:		ALEXANDRIA REAL ESTATE EQUITIES, L.P., a Delaware limited partnership, member
			
			By:		ARE-QRS CORP., a
					 Maryland corporation,
 general
partner

				
					By:		 /s/ Eric Johnson

					Name:		 Eric Johnson

					Its:		 Senior Vice President,

							 RE Legal Affairs

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

  
 5 

 EXHIBIT C TO LEASE 

AMENDED AND RESTATED WORK LETTER 

See attached 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

  
 6 

 AMENDED AND RESTATED WORK LETTER 

This Amended and Restated Work Letter (this “Work Letter”) is made and entered into as of March 24, 2015, by and between
ARE-MA REGION NO. 48, LLC, a Delaware limited liability company (“Landlord”), and ARIAD Pharmaceuticals, Inc., a Delaware corporation (“Tenant”), and is attached to and made a part of that Lease dated as of
January 4, 2013, amended by a First Amendment to Lease dated as of September 16, 2013, and by that certain Second Amendment to Lease dated as of the date hereof (as the same may be amended, amended and restated, supplemented or otherwise
modified from time to time, the “Lease”), by and between Landlord and Tenant for premises at 75 Binney Street and 125 Binney Street in Cambridge, Massachusetts. All capitalized terms used but not otherwise defined herein shall have
the meanings given them in the Lease, as so amended. This Work Letter amends, restates, and supersedes in its entirety the Work Letter attached to the Lease, as such Work Letter was amended by the First Amendment to Lease. 

1 GENERAL REQUIREMENTS 
  

	1.1	Authorized Representatives. Landlord designates as Landlord’s authorized representatives (each, “Landlord’s Authorized Representative”), Tom Andrews, Joseph Maguire, Andrew Reinach, and
William DePippo each of whom is authorized to issue to Tenant and to initial and sign, as applicable, all plans, drawings, approvals and Changes (as defined below) pursuant to this Work Letter. Tenant shall not be obligated to respond to or act upon
any such item until such item has been initialed or signed (as applicable) by any of Landlord’s Authorized Representatives. Landlord may change Landlord’s Authorized Representatives upon two (2) business days’ prior written
notice to Tenant. A Landlord’s Authorized Representative shall personally attend all design and construction meetings for the Project Improvements as reasonably noticed by Landlord’s or Tenant’s Authorized Representatives.

  

	1.1.1	Tenant designates as Tenant’s authorized representatives (each, “Tenant’s Authorized Representative”), Philip Plottel and Edward Fitzgerald, each of whom is authorized to issue to, initial and
sign, as applicable, all plans, drawings, approvals and Changes pursuant to this Work Letter. Landlord shall not be obligated to respond to or act upon any such item until such item has been initialed or signed (as applicable) by Tenant’s
Authorized Representative. Tenant may change Tenant’s Authorized Representative upon two (2) business days’ prior written notice to Landlord. Tenant’s Authorized Representative shall personally attend, and have access to meeting
notes (except notes related to the cost of the Non-TI Project Improvements) of, all design and construction meetings for the Project Improvements, as noticed by Landlord’s or Tenant’s Authorized Representative. 

 

	1.2	Applicable Response Period. For purposes of this Work Letter, the “Applicable Response Period” shall mean the applicable number of days for a party to respond to a submission or a request for an
approval as provided in this Work Letter, or, if no such period is set forth in this Work Letter, five (5) business days after receipt of the submission or request for approval. 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

	1.3	Consents. Any refusal of consent by Landlord or Tenant shall specify in reasonable detail the reasons for such disapproval. No request shall be “deemed approved” unless the request for consent specifies
in all capital letters as follows: “CONSENT TO THE MATTERS SET FORTH HEREIN SHALL BE DEEMED GIVEN IF NO RESPONSE IS PROVIDED WITHIN [            DAYS; specify relevant number of
days] OF THE DATE HEREOF”. 

 2 LANDLORD’S CONSTRUCTION OF THE NON-TI PROJECT IMPROVEMENTS 

 

	2.1	Landlord shall construct the following improvements on the Project (collectively, the “Non-TI Project Improvements”; also referenced in the Lease as “Landlord’s Work”):
(i) shell and core improvements for the Buildings, including the lobbies and underground parking (the “Shell and Core Improvements”) in accordance with the updated plans and specifications and Landlord/Tenant Responsibility
Matrix referenced in Schedule 2.1 (the “Shell, Core and Site Construction Documents”); and (ii) all landscaping, plaza areas, walkways, driveways, sidewalks, and other improvements for the Project (the “Site
Improvements”; the Shell and Core Improvements and the Site Improvements, collectively, the “Shell, Core and Site Improvements”) in accordance with the Site Plans set forth in Schedule 2.1 (“Site
Plans”). Landlord shall construct the Non-TI Project Improvements at its sole cost and expense, except as otherwise expressly set forth herein. The cost of the Tenant Improvements to be undertaken by Tenant shall be paid for in accordance
with Section 6 below. 

  

	2.2	Non-TI Project Improvements. Landlord’s construction of the Non-TI Project Improvements shall be effected by contractors selected and retained by Landlord, pursuant to the Shell, Core and Site Construction
Documents, as the same may be further modified as provided in Sections 2.3 and 2.4 below, to include any Landlord Modifications and Approved Tenant Modifications (as each such term is defined below) and/or as required by any applicable
Governmental Authorities. 

  

	2.2.1	Project Architect. Landlord has engaged Payette as the architect for the Non-TI Project Improvements (the “Project Architect”). 

 

	2.2.2	Construction Manager for Non-TI Project Improvements. Landlord has engaged Gilbane Building Company as the construction manager for the construction of the Non-TI Project Improvements (“Construction
Manager”). Any change in the Construction Manager shall be subject to Tenant’s approval, not to be unreasonably withheld or delayed. 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

	2.3	Landlord Modifications to Shell, Core and Site Construction Documents. 

 It is
anticipated that prior to and during construction of the Non-TI Project Improvements, Landlord may reasonably require changes to the Shell, Core and Site Construction Documents as Landlord shall desire and/or as may be required to obtain building
permits and other governmental approvals and comply with Applicable Laws. Landlord shall be entitled, from time to time, to make any such changes to the Shell, Core and Site Construction Documents (collectively, the “Landlord
Modifications”), without Tenant’s consent, so long as such Landlord Modifications, if implemented, would not: (i) effect material changes to the design of the Shell, Core and Site Improvements previously approved by Tenant
(including the exterior appearance thereof); (ii) adversely affect Tenant’s contemplated use or occupancy of the Building for the Permitted Uses; or (iii) create a Landlord Impact (collectively, an “Adverse
Condition”). In the event any such Landlord Modification, if implemented, would be reasonably likely to create an Adverse Condition, Landlord shall notify Tenant of such Landlord Modifications prior to implementation thereof (which notice
shall include Landlord’s description of the Adverse Condition, and the adverse effects and impacts which Landlord believes comprise such Adverse Condition to the extent then known or reasonably anticipated by Landlord), and any reasonable
alternatives, and Tenant shall, within five (5) business days after receipt of Landlord’s notice, notify Landlord of Tenant’s approval or reasonable disapproval thereof with specified reasons for such disapproval. Tenant’s
failure to notify Landlord of its approval or reasonable disapproval within such 5-business day period shall be deemed Tenant’s approval of such proposed Landlord Modifications. For purposes of determining whether a Landlord Modification would
create an Adverse Condition pursuant to the foregoing, an “Adverse Condition” shall also include any material delays in Substantial Completion of the Non-TI Project Improvements beyond the Target Commencement Date specified in the Lease;
provided, however, to the extent a Landlord Modification is necessary to comply with Applicable Laws or is required by any applicable Governmental Authorities in connection with its enforcement of Applicable Laws, such Landlord
Modification shall not constitute an Adverse Condition. 
  

	2.4	Tenant-Requested Modifications to Shell, Core and Site Construction Documents. 

 To the
extent set forth in the Shell, Core and Site Construction Documents, Tenant has requested, and Landlord has approved, changes to the Shell, Core and Site Construction Documents desired by Tenant. Tenant shall have no further right to request any
Tenant-Requested Modifications. 
  

	2.5	Omitted 

  

	2.6	Approved Tenant Modifications. 

 Any Tenant-Requested Modification which Landlord has
incorporated into the Shell, Core and Site Construction Documents shall be referred to herein as an “Approved Tenant Modification”. Landlord has performed the design and construction of such Approved Tenant Modifications as a “TI
Cost” for the purpose of Article 6 below. Landlord and Tenant confirm their agreement with respect to the substance and pricing of such Tenant-Requested Modifications as described on Schedule 2.6 hereof. The parties hereby confirm that
there shall be charged against the Tenant Allowance the cost of Tenant-Requested Modifications in accordance with Schedule 2.6 hereof. 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

	2.7	Shared Staffing Costs During Construction. 

 It had been anticipated that, during the
construction process under the original Work Letter, in which Landlord was constructing both the Non-TI Project Improvements and the Tenant Improvements, Landlord would share with the Construction Manager’s team undertaking the TI Improvements
certain staffing, the cost of which was to be reasonably allocated between the Non-TI Project Improvements and the TI Improvements. Due to the Tenant Delay in the prosecution of the Tenant Improvements, the Non-TI Project Improvements and Tenant
Improvements were not prosecuted by Landlord as a single project. Tenant’s portion of such staffing is a cost for which Tenant is responsible. The parties hereby confirm that there shall be charged against the Tenant Allowance the cost of such
staffing which would have been allocated to the Tenant during the construction by Landlord of the Non-TI Project Improvements and the Tenant Improvements in accordance with Schedule 2.7. 

 

	2.8	Substantial Completion of the Non-TI Project Improvements. 

 For purposes of this Work
Letter, the term “Substantially Completed” or “Substantial Completion” as to the Non-TI Project Improvements shall occur upon: (i) the substantial completion of construction of the Shell and Core Improvements; and any Punch
List Items for the Shell and Core Improvements, which Punch List Items shall be diligently completed by Landlord not later than thirty (30) days thereafter, provided that such Punch List Items (as defined below) which arise due to a delayed
delivery of such item or material portion thereof shall be completed not later than ninety (90) days after Substantial Completion (except for exterior items affected by seasonal conditions, which shall be completed as soon as practicable));
(ii) the Building systems included in the Shell and Core are tested and ready for operation, to the extent feasible given the absence of Tenant Improvements or plans therefor; (iii) a temporary Certificate of Occupancy (sufficient for
Tenant’s installation of the Tenant Improvements) for the Shell and Core has been issued by the applicable Governmental Authority; (iv) Landlord is able to provide parking for Tenant sufficient to satisfy the parking requirements under the
Lease for the Premises in the Building Parking Garage; (v) Landlord is able to provide Tenant reasonable and continuous ingress and egress to and from the parking areas and the Premises, (vi) continuous and uninterrupted power is available
to the Premises; (vii) main interior fire protection, main electrical and main mechanical core improvements have been completed, to the extent feasible given the absence of Tenant Improvements or plans therefor; (viii) the Premises is in
“watertight” condition; (ix) the elevators in the Buildings have been installed and are available for unrestricted use by Tenant to the extent feasible given the absence of Tenant Improvements or plans therefor; and (x) the
Project Architect has executed a Certificate of Substantial Completion for the Shell and Core Improvements in the form of the American Institute of Architects (“AIA”) document G704 with respect to the Non-TI Project Improvements, subject
to the qualifications set forth in this Section 2.8. The term “Punch List Items” shall mean minor items of completion, correction or repair with respect to the Shell and Core Improvements, which by their nature will not
interfere with, or impair in any material respect, Tenant’s installation of the Tenant Improvements in the Premises. 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

 The parties hereby confirm that as of March 24, 1015 the Non-TI Project Improvements have
been Substantially Completed. The agreed upon Punch List Items as of March 24, 2015 are listed in the attached Schedule 2.8(a). Except as set forth in Schedule 2.8(a), the Punch List Items shall be diligently completed by Landlord
not later than thirty (30) days after the date hereof, provided that such Punch List Items which arise due to a delayed delivery of such item or material portion thereof shall be completed not later than ninety (90) days after Substantial
Completion, or the later date therefor set forth on Schedule 2.8(a) (except for exterior items affected by seasonal conditions, which shall be completed as soon as practicable)). As soon as the same become available, Landlord shall provide
Tenant with all commissioning reports and protocols, “as built” drawings (CAD and BIM), balancing reports, and interim and final engineering summary, analysis, conclusions and recommendations as reasonably required for design and
completion of the Non-TI Project Improvements and the Tenant Improvements. Landlord and Tenant shall review all of the same together and shall cooperate to set forth and require Landlord’s contractors to add such additional Punch List Items as
are reasonably required for actual final completion of the Non-TI Project Improvements. The completion of the Site Improvements was not a condition precedent to the Substantial Completion of the Non-TI Project Improvements, it being agreed that the
completion of the Site Improvements may be deferred by Landlord to accommodate construction of improvements at 270 Third Street and the Binney Street Area Infrastructure Project. The Site Improvements are anticipated to be completed in accordance
with the exterior work phasing plan attached hereto as Schedule 2.8(b). In the event that either of the two (2) phases of the Site Improvements have not been completed within 180 days after the scheduled completion date for each such
phase, as set forth in Schedule 2.8 (as such date may be extended by Force Majeure and any Tenant Delays), the sole remedy of Tenant therefor shall be the exercise of Tenant’s remedies under Section 31(b) of the Lease. 

3 TENANT IMPROVEMENTS 
 As used in this
Work Letter, “Tenant Improvements” shall mean and refer to all improvements to the Premises desired by Tenant of a fixed and permanent nature. Other than funding the TI Allowance in accordance with Section 6 below,
Landlord shall not have any obligation whatsoever with respect to the finishing of the Premises for Tenant’s use and occupancy. Tenant may undertake the Tenant Improvements in phases (each, a “TI Phase”) to accommodate
Tenant’s phased occupancy of the Premises, or Tenant’s subleasing thereof. In such event, the provisions of this Section 3 shall be applicable to each such TI Phase. At the time of approval of the TI Construction Documents,
Landlord and Tenant shall mutually agree upon the schedule for performance and completion by Tenant of the Tenant Improvements (or TI Phase) (“Anticipated TI Schedule”). 

 

	3.1	Selection of Architects, Consultants and Contractors for Tenant Improvements 

 Landlord
and Tenant hereby acknowledge and agree that the architect (the “TI Architect”) for the Tenant Improvements, the general contractor and any subcontractors for the 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

 
Tenant Improvements shall be selected by Tenant, subject to Landlord’s approval, which approval shall not be unreasonably withheld, conditioned or delayed. Landlord shall be named a third
party beneficiary of any contract entered into by Tenant with the TI Architect, any consultant, any contractor or any subcontractor, and of any warranty made by any contractor or any subcontractor. Landlord hereby approves Payette Architects and
Chan Mock Architects as the TI Architect. Landlord further consents to Tenant’s selection of the general contractor for the Tenant Improvements from the general contractors listed on Schedule 3.1. 

 

	3.2	Tenant’s Design Drawings. 

 Tenant shall deliver to Landlord schematic drawings and
outline specifications (the “TI Design Drawings”) detailing Tenant’s requirements for the Tenant Improvements (or the applicable TI Phase) on a schedule determined by Tenant. Not more than 5 business days thereafter, Landlord
shall deliver to Tenant the written objections, questions or comments of Landlord with regard to the TI Design Drawings. Tenant shall cause the TI Design Drawings to be revised to address such written comments and shall resubmit said drawings to
Landlord for approval within 5 business days thereafter. Such process shall continue until Landlord has approved the TI Design Drawings. 
  

	3.3	Working Drawings. 

 Following the approval of the TI Design Drawings by Landlord, Tenant
shall cause the TI Architect to prepare and deliver to Landlord for review and comment construction plans, specifications and drawings for the Tenant Improvements (or the applicable TI Phase) (“TI Construction Drawings”), which TI
Construction Drawings shall be prepared substantially in accordance with the TI Design Drawings. Tenant shall be solely responsible for ensuring that the TI Construction Drawings reflect Tenant’s requirements for the Tenant Improvements.
Landlord shall deliver its written comments on the TI Construction Drawings to Tenant not later than 5 business days after Landlord’s receipt of the same; provided, however, that Landlord may not disapprove any matter that is consistent with
the TI Design Drawings. Tenant and the TI Architect shall consider all such comments in good faith and shall, within 5 business days after receipt, notify Landlord how Tenant proposes to respond to such comments. Any disputes in connection with such
comments shall be resolved in accordance with Section 3.4 hereof. Provided that the design reflected in the TI Construction Drawings is consistent with the TI Design Drawings, Landlord shall approve the TI Construction Drawings submitted
by Tenant. Once approved by Landlord, subject to the provisions of Section 3.8 below, Tenant shall not materially modify the TI Construction Drawings except as may be reasonably required in connection with the issuance of the TI Permit
(as defined in Section 3.7 below). 
  

	3.4	Approval and Completion. 

 If any dispute regarding the design of the Tenant
Improvements is not settled within 10 business days after notice of such dispute is delivered by one party to the other, Tenant may make the final decision regarding the design of the Tenant Improvements, provided (i) Tenant acts reasonably and
such final decision is either consistent with or a compromise between 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

 
Landlord’s and Tenant’s positions with respect to such dispute, (ii) that all costs and expenses resulting from any such decision by Tenant shall be payable as provided in
Section 6 below; and (iii) Tenant’s decision will not affect the base Building, structural components of the Building or any Building systems (in which case Landlord shall make the final decision). Any changes to the TI
Construction Drawings following Landlord’s and Tenant’s approval of same requested by Tenant shall be processed as provided in Section 3.8 hereof. 
  

	3.5	Landlord’s Review of Tenant Improvement Plans and Review of Tenant Improvement Construction. 

Any review of the TI Design Drawings or the TI Construction Drawings by Landlord, Landlord’s Authorized Representative, the Project
Architect or anyone else acting on Landlord’s behalf, including without limitation construction advisors, design professionals, contractors and subcontractors (collectively, “Landlord’s Agents”), shall be for
Landlord’s sole purpose and shall not imply Landlord’s review of the same (or obligate Landlord to review the same) for quality, design, compliance with Applicable Laws or other like matters. Neither Landlord, Landlord’s Authorized
Representatives nor any of Landlord’s Agents shall have any liability whatsoever in connection with, and shall not be responsible for any omissions or errors contained in the TI Design Drawings or the TI Construction Drawings (collectively, the
“Tenant Plans”) as a result of any inspections or review thereof. Throughout the construction of any Tenant Improvements, Landlord shall have the right, at its sole cost and expense, on not less than two (2) business
days’ advance notice to Tenant, and, if specified by Tenant at Tenant’s option, accompanied by a representative of Tenant, to inspect the construction of the Tenant Improvements; provided that no such inspections shall interfere with or
otherwise delay Tenant’s construction of the Tenant Improvements. Without limitation of the foregoing, Landlord shall be permitted to have representatives attend Tenant’s weekly project meetings during the construction of the Tenant
Improvements for coordination purposes, and shall receive copies of all meeting minutes at the time of their issuance. 
  

	3.6	Compliance with LEED Standards. 

 All plans prepared by Tenant and the TI Architect for
the Tenant Improvements shall comply with the LEED standards set forth in Schedule 3.6. 
  

	3.7	Performance of Tenant Improvements. 

 (a) Commencement and Permitting
of the Tenant Improvements. Tenant shall commence construction of the Tenant Improvements (or the applicable TI Phase) upon obtaining and delivering to Landlord a building permit (the “TI Permit”) authorizing the construction of
the Tenant Improvements (or the applicable TI Phase), consistent with the TI Construction Drawings approved by Landlord, and shall thereafter prosecute the same to completion in accordance with the Anticipated TI Schedule, subject to Force Majeure
and any Landlord Impacts. The cost of obtaining the TI Permit shall be payable as provided in Section 6 below. Prior to the commencement of the Tenant Improvements, Tenant shall deliver to Landlord a copy of all contracts with
Tenant’s contractors (including the TI Architect), and 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

 
certificates of insurance from any contractor performing any part of the Tenant Improvement evidencing industry standard commercial general liability, automotive liability, “builder’s
risk”, and workers’ compensation insurance. Tenant shall cause the general contractor to provide a certificate of insurance naming Landlord, Alexandria Real Estate Equities, Inc., and Landlord’s lender (if any) as additional insureds
for the general contractor’s liability coverages required above. In addition, Tenant shall provide to Landlord a certificate of insurance evidencing the professional liability and commercial general liability insurance policies of the TI
Architect. 
 (b) Selection of Materials, Etc. Where more than one type of material or structure is indicated on the
TI Construction Drawings approved by Tenant and Landlord, the option will be within Tenant’s reasonable discretion if the matter concerns the Tenant Improvements, and within Landlord’s sole and absolute subjective discretion if the matter
concerns the structural components of the Building or any Building system. 
 (c) Tenant Liability. Tenant shall be
responsible for correcting any deficiencies or defects in the Tenant Improvements. 
 (d) Substantial Completion of the
Tenant Improvements. Tenant shall diligently prosecute and substantially complete or cause to be substantially completed the Tenant Improvements (or the applicable TI Phase) in a good and workmanlike manner, in accordance with the TI Permit and
Tenant’s contracts, subject, in each case, to Minor Variations and normal “punch list” items of a non-material nature which do not interfere with the use of the Premises (“TI Substantial Completion” or “TI
Substantially Complete”). Tenant shall obtain and deliver to Landlord a Certificate of Occupancy for the Tenant Improvements (or applicable TI Phase) as a condition precedent to TI Substantial Completion. Upon TI Substantial Completion,
Tenant shall require the TI Architect and the general contractor to execute and deliver, for the benefit of Tenant and Landlord, a Certificate of Substantial Completion in the form of the American Institute of Architects (“AIA”)
document G704. For purposes of this Work Letter, “Minor Variations” shall mean any modifications reasonably required: (i) to comply with all applicable Legal Requirements and/or to obtain or to comply with any required permit
(including the TI Permit); (ii) to comport with good design, engineering, and construction practices which are not material; or (iii) to make reasonable adjustments for field deviations or conditions encountered during the construction of
the Tenant Improvements. 
  

	3.8	Changes to the Tenant Improvements 

 Any changes to the Approved TI Construction
Documents (each, a “Change”) shall be requested and instituted in accordance with the provisions of this Section 3.8 and shall be subject to the written approval of Landlord to the extent required under this Work Letter.

  

	3.8.1	 Change Request. Tenant may request Changes after Landlord approves the Approved TI Construction Documents by notifying Landlord in writing in
substantially the same form as the AIA standard change order form (a “Change Request”), which Change Request shall detail the nature and extent of any requested Changes, including (a) the Change, (b) the estimated net
incremental cost of the Change and (c) any modification of the 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

	 	
Approved TI Construction Documents necessitated by the Change. Change Requests shall be signed by Tenant’s Authorized Representative. In no event shall Landlord be required to approve any
Change Request from Tenant that: (i) is inconsistent with the Approved TI Construction Documents; or (ii) could, in Landlord’s reasonable opinion, result in a Future Tenanting Impact (as defined below), unless Tenant agrees to remove
and restore prior to expiration of Lease Term, at Tenant’s sole cost and expense, the portion of the Tenant Improvements constructed as part of such Change which causes the Future Tenanting Impact, pursuant to Landlord’s requirements for
elimination of such Future Tenanting Impact as the same are specified by Landlord at the time such Change Request is made under this Section 3.8.1, provided further, that no deduction from the rentable square footage of the Premises for
purposes of determination of Base Rent payable under the Lease, which would otherwise apply under the Lease, shall be made as a result of any vertical penetrations required by or as a part of such Change. A “Future Tenanting Impact” shall
mean, in Landlord’s reasonable opinion, that a Tenant-Requested Modification would be reasonably likely to materially adversely affect the future re-tenanting of either of the Buildings as a either single-tenant or multi-tenant buildings.
Notwithstanding the foregoing, Tenant may make Changes which (i) do not affect Building systems or structure and (ii) which would not reasonably be expected to cause a Future Tenanting Impact (“Notice-Only Changes”) which do not
materially alter the nature of the Approved TI Construction Document having a cost of up to $[***] for any phase of the Tenant Improvements, provided that Tenant notifies Landlord in writing of such intended Notice-Only Change, and such notice shall
be accompanied by plans, specifications (including sketches and similar construction detail documents), work contracts and such other information concerning the nature and cost of the Notice-Only Change as may be reasonably requested by Landlord,
which notice and accompanying materials shall be delivered to Landlord not less than 5 business days in advance of any proposed construction thereof. 

  

	3.8.2	Approval of Changes. All Change Requests shall be subject to Landlord’s prior written approval, which approval shall not be unreasonably withheld, conditioned or delayed. Landlord shall have 5 business days
after receipt of a Change Request to notify Tenant in writing of Landlord’s decision either to approve or object to the Change Request. Landlord’s failure to respond within such 5 business day period shall be deemed approval by Landlord.
Any costs related to a Change for which Tenant is responsible under this Section 3.8 shall be paid for in accordance with the provisions of Section 6 below. 

4 EXCUSED DELAYS 
  

	4.1	Construction Force Majeure. As used herein and in the Lease, “Construction Force Majeure” shall have the same meaning as “Force Majeure” set forth in Section 34 of the Lease.

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

	4.2	Tenant Delay. 

  

	4.2.1	As used herein and in the Lease and subject to Sections 4.2.2 and 4.2.3 hereof, “Tenant Delay” shall mean any actual delay in Landlord’s achievement of Substantial Completion of the Non-TI
Project Improvements as a result of any one or more of the following: (i) Tenant’s failure to respond within time limits specified in this Work Letter as to matters requiring Tenant’s approval unless such failure to respond is deemed
approval or disapproval of such matter pursuant to the terms of this Work Letter; (ii) any delays due to Tenant-Requested Modifications to the extent not arising due to Landlord Impacts, (v) any delays caused by Tenant or Tenant’s
Agents (as defined in Section 5.3.2 below); and/or (vi) Tenant’s failure to timely comply with its obligations under this Work Letter and/or the Lease to the extent such failure is not caused by any Construction Force Majeure
delays encountered by Tenant with respect thereto. Landlord confirms that the Commencement Date is as set forth in the Second Amendment, and there is not any Tenant Delay except as agreed upon in connection with the establishment of Schedule 6.6 to
this Work Letter and the mutual agreement upon the Commencement Date. 

  

	4.2.2	Landlord shall use commercially reasonable efforts to mitigate the effects of any claimed Tenant Delay, and shall provide reasonable information and alternatives to Tenant to assist in such mitigation efforts;
provided, however, Landlord shall not be required to incur any material cost or incur any material liability in seeking to mitigate any Tenant Delay. 

 

	4.2.3	No Tenant Delay shall be deemed to have occurred hereunder unless Landlord shall have delivered notice to Tenant of such Tenant Delay after Landlord has actual knowledge of the circumstances giving rise to such Tenant
Delay, which notice shall reasonably set forth the circumstances giving rise to such Tenant Delay. The period of Tenant Delay shall not commence until the date two (2) business days after the date on which such notice shall have been delivered
to Tenant. Landlord shall give Tenant notice of the occurrence of (or of the existence of any conditions which would cause) a Tenant Delay with reasonable promptness after Landlord has received actual knowledge thereof in order to provide to Tenant
an opportunity to end, to avoid or to minimize the consequences of any such Tenant Delay. 

 Notwithstanding anything to the
contrary contained herein, no delay shall constitute a Tenant Delay to the extent such delay: (i) occurs by reason of a Landlord Impact (as defined below); (ii) does not result in actual “net” delay in completion of the Project;
(iii) has been compensated for by Tenant by payment of overtime or other charges to make up the delay, or otherwise; or (iv) is caused by Construction Force Majeure. The term “Landlord Impact” shall mean any of the
following occurrences: (a) Landlord’s failure to provide a response required of Landlord within the time periods set forth in this Work Letter unless such failure to respond is deemed approval or disapproval of such matter pursuant to the
terms of this Work Letter, (b) any changes to the approved Non-TI Project Improvements Construction Documents made or requested by Landlord to the extent not arising due to a Tenant Change, or (c) Landlord’s failure to comply with its
obligations in accordance with this Work Letter. 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

 5 CERTAIN REQUIREMENTS APPLICABLE TO CONSTRUCTION OF THE PREMISES 

Landlord shall comply with the following requirements in connection with its construction of the Premises: 

 

	5.1	Condition of Construction 

 Landlord hereby agrees to complete the construction of the
Non-TI Project Improvements in accordance with the Shell, Core and Site Construction Documents and in compliance with Applicable Laws in effect as of the date of the building permit therefor, free of material defects and otherwise in good condition
and working order. 
  

	5.2	Construction Warranties and Insurance 

 Landlord shall incorporate only new materials
and equipment into the construction of the Non-TI Project Improvements. Landlord warrants and guarantees (i) the Non-TI Project Improvements will be completed in substantial accordance with the approved Shell, Core and Site Construction
Documents (as the same may be modified by Changes approved hereunder) and free of defective workmanship and materials and (ii) the Non-TI Project Improvements (other than any Tenant-Requested Modifications) shall be free of design defects
(“Landlord’s Warranty”). The Landlord’s Warranty shall survive and remain in effect for a period of one (1) year after the date of Substantial Completion of the Non-TI Project Improvements (the “Warranty
Period”). Landlord shall, at its sole cost and expense, promptly correct or cause to be corrected (i) any defect in the Non-TI Project Improvements, including, without limitation, any defects arising from Landlord’s failure to
complete the Non-TI Project Improvements in substantial accordance with the approved Shell, Core and Site Construction Documents (as the same may be modified by Changes approved hereunder), or (ii) any material deviation from the approved
Shell, Core and Site Construction Documents (each, a “Non-TI Project Defect” and, collectively, the “Non-TI Project Defects”), provided that Tenant notifies Landlord of any Non-TI Project Defect within the Warranty
Period. Landlord’s Warranty shall be in addition to the warranties provided by contractors and suppliers as set forth in Schedule 5.2, but Landlord’s Warranty shall be the sole and exclusive warranty provided by Landlord with
respect to the Non-TI Project Improvements (subject to the provisions set forth in the Lease, including Section 5 and Section 13 thereof). Nothing in this Section 5.2 shall be construed as limiting or restricting
in any way Landlord’s right to seek reimbursement from (x) professionals and contractors who are parties to the relevant contracts and/or (y) insurance companies for costs incurred by Landlord to correct any Non-TI Project Defects.
Upon the expiration of the Warranty Period, Landlord shall assign to Tenant all surviving and assignable guaranties and warranties of workmanship or materials given by any contractor, subcontractors, architects, engineers or materialmen that
guarantee or warrant against defective design, workmanship or materials for a period of time in excess of the Warranty Period in connection with the construction of the Non-TI Project Improvements and shall thereafter cooperate with Tenant, at no
cost to Landlord, in the enforcement of any such guaranties and warranties, but Landlord shall not otherwise be responsible for any Non-TI Project Defects after the Warranty Period. Landlord shall obtain and

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

 
maintain builder’s risk/course of construction insurance coverage during Landlord’s construction of the Non-TI Project Improvements in commercially reasonable amounts and with customary
coverages commensurate with the size and scope of the construction project contemplated by this Work Letter issued by financially viable and licensed insurers, and shall provide a certificate evidencing the same to Tenant upon request therefor.
Tenant shall obtain and maintain builder’s risk/course of construction insurance coverage during Tenant’s construction of the Tenant Improvements (or TI Phase) in commercially reasonable amounts and with customary coverages commensurate
with the size and scope of the construction project contemplated by this Work Letter issued by financially viable and licensed insurers, as approved by Landlord prior to the commencement of work, and shall provide a certificate evidencing the
same to Landlord upon request therefor prior to the commencement of any work in the Premises. 
  

	5.3	Tenant Entry upon Premises. 

  

	5.3.1	Tenant Review of Project Construction Prior to Commencement Date. Throughout the construction of the Non-TI Project Improvements, Tenant shall have the right, at its sole cost and expense, on not less than two
(2) business days’ advance notice to Landlord, and, if specified by Landlord at Landlord’s option, accompanied by a representative of Landlord, to inspect the construction of the Non-TI Project Improvements; provided that no such
inspections shall interfere with or otherwise delay Landlord’s construction of the Non-TI Project Improvements. Any review of the Shell, Core and Site Construction Documents by Tenant, Tenant’s Authorized Representative or anyone acting on
Tenant’s behalf, including without limitation construction advisors or design professionals (collectively, “Tenant’s Agents”), and/or any inspections of the Non-TI Project Improvement construction by Tenant, Tenant’s
Authorized Representative, or Tenant’s Agents, shall be for Tenant’s sole purpose and shall not imply Tenant’s review of the same (or obligate Tenant to review the same) for quality, design, compliance with Applicable Laws or other
like matters. Neither Tenant, Tenant’s Authorized Representatives nor any of Tenant’s Agents shall have any liability whatsoever in connection with, and shall not be responsible for any omissions or errors contained in the Shell, Core and
Site Construction Documents as a result of any inspections or review thereof. 

  

	5.3.2	Tenant Entry Upon Premises From and After Commencement Date. From and after the Commencement Date, Tenant shall have access to the Premises 24 hours per day, 7 days per week, subject to a right of entry on the
part of Landlord to complete any outstanding Punch List Items, to perform inspections and attend meetings in accordance with Section 3.5, and to otherwise perform the obligations of Landlord under the Lease. 

 

	5.3.3	 Entry Requirements. In connection with Tenant’s entry onto the Premises pursuant to this Section 5.3 above and as a condition
thereto, Tenant shall secure and maintain, and cause each of its contractors entering upon the Premises in connection with the Tenant’s Work to maintain, at Tenant’s sole cost, a commercial general liability and property damage insurance
policy covering Tenant’s and Tenant Agent’s activities on the Premises, which shall conform with the provisions of Section 17 of the Lease. Tenant 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

	 	
and its contractors shall maintain workers’ compensation insurance as required by law. The insurance policies to be provided by Tenant hereunder shall name Landlord and Alexandria Real
Estate Equities, Inc. as additional insureds and shall conform with the requirements of Section 22.4 of the Lease and Tenant shall be required to notify Landlord not later than thirty (30) days’ prior to any termination of such
policies if such termination will become effective prior to the Term Commencement Date. All insurance policies of Tenant and its contractors shall be on a per project basis. Tenant shall deliver to Landlord certificates of such insurance as a
condition precedent to Tenant’s entry onto the Premises pursuant to Section 5.3.1 above. Landlord and Tenant shall cause their respective contractors to reasonably cooperate with each other in the exercise of their rights of entry
under this Section 5.3. Tenant and any of Tenant’s Agents entering upon the Premises hereunder shall comply with all established jobsite and safety rules and practices of Landlord’s contractor and Landlord until completion of
the Non-TI Project Improvements and acceptance thereof by Tenant. If Landlord determines in good faith that the entry or activities of Tenant upon the Project or the Premises hereunder is materially interfering with or delaying the completion of the
Non-TI Project Improvements or any inspections or issuance of final approvals by applicable governmental authorities, Landlord may upon notice to Tenant suspend such entry and activities. 

6 COSTS 
  

	6.1	Budget For Tenant Improvements. Before the commencement of construction of the Tenant Improvements (or any TI Phase), Tenant shall obtain a detailed breakdown, by trade, of the costs incurred or that will be
incurred, in connection with the design and construction of the Tenant Improvements (or such TI Phase) (the “Budget”), and deliver a copy of the Budget to Landlord for Landlord’s approval, which shall not be unreasonably withheld or
delayed. The Budget shall be based upon the TI Construction Drawings approved by Landlord and shall include a payment to Landlord of administrative rent (“Administrative Rent”) equal to $[***] per rentable square foot (i.e., [***]% of
$[***] per rentable square foot) for monitoring and inspecting the construction of the Tenant Improvements, which lump sum shall be payable from the TI Allowance on a percentage of completion basis. Such Administrative Rent shall include, without
limitation, all out-of-pocket costs, expenses and fees incurred by or on behalf of Landlord arising from, out of, or in connection with, such monitoring of the construction of the Tenant Improvements (or the Tenant Improvements for such phase), and
shall be payable as provided in this Section 6. If the Budget is greater than the TI Allowance (or the TI Allowance allocable to such TI Phase), Tenant shall pay Tenant’s Proportionate Share (as defined in Section 6.7
below) thereof. 

  

	6.2	 Base TI Allowance. Landlord shall provide to Tenant a tenant improvement allowance (the “Base TI Allowance”) of $[***] per
rentable square foot of the Premises (exclusive of the New Atrium Area), or $[***] in the aggregate, to be used for TI Costs (as defined below). The Base TI Allowance for the initial Premises and the Expansion Space may be used for any portion of
the Premises (including the Expansion Space, but excluding the 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

	 	
New Atrium Area), provided that at all times there remains in the unused Base TI Allowance the sum of $[***] per rentable square foot of the Premises not being improved for use by ARIAD
Pharmaceuticals, Inc. or a permitted subtenant thereof in accordance with the provisions of this Work Letter (“Unused Base TI Allowance Minimum Amount”). 

 

	6.3	Additional TI Allowance; Base Rent Allocable to Additional TI Allowance. If elected by Tenant, Landlord shall provide to Tenant an additional tenant improvement allowance (the “Additional TI Allowance’;
with the Base TI Allowance, the “TI Allowance”) of $[***] per rentable square foot of the Premises (exclusive of the New Atrium Area), or $[***] in the aggregate, to be used by Tenant for TI Costs for ARIAD Pharmaceuticals, Inc. or a
permitted subtenant thereof. Base Rent allocable to the entire Additional TI Allowance (“Additional TI Base Rent”) shall be payable solely with respect to each requisition of the Additional TI Allowance that is actually funded by Landlord.
Such portion of Additional TI Base Rent shall be amortized over the then remaining initial Term of the Lease at an interest rate of [***]% per annum, and shall be payable as follows: (a) during the Anticipated TI Project Schedule for
construction of the Tenant Improvements (or applicable TI Phase), Tenant shall pay monthly, as Additional TI Base Rent, interest only on such portion of the Additional TI Allowance as has been advanced therefor; and (b) from and after the
scheduled date for TI Substantial Completion as set forth on the Anticipated TI Schedule, Additional TI Base Rent shall be increased by the amount necessary to amortize such Additional TI Allowance over the then remaining initial Term of the Lease
at an interest rate of [***]% per annum. 

  

	6.4	Notice As to Use of TI Allowance. Tenant shall have the right to availability of all or any portion of the TI Allowance by requisitions made any time up through the fifth ([5th]) anniversary of the Commencement Date. 

  

	6.5	Use of TI Allowance. The TI Allowance shall be disbursed in accordance with this Work Letter. Tenant shall have no right to the use or benefit (including any reduction to or payment of Base Rent) of any portion
of the TI Allowance not required for payment of TI Costs as defined below. Tenant may use the TI Allowance for the improvement of subtenant space prior to the execution of a permitted sublease for such space, subject to the terms of this Work
Letter, provided that in all events there remains undisbursed from the Base TI Allowance the Unused Base TI Allowance Minimum Amount. 

  

	6.6	 Costs Includable in TI Allowance. The TI Allowance shall be used solely for TI Costs. The term “TI Costs” shall mean: (a) the
aggregate cost of designing, engineering, permitting, consulting, and constructing the Tenant Improvements in the Premises (exclusive of the New Atrium Area) to the extent actually incurred, including, without limitation: (i) the cost of
preparing any Tenant Plans (including the costs of specialty design and engineering consultants); (ii) all costs set forth in the Budget, including Landlord’s Administrative Rent, Landlord’s reasonable out-of-pocket expenses, costs
resulting from Tenant Delays; and (iii) the cost of Changes pursuant to Section 3.4; and (iv) approved moving expenses; and (b) the cost of any Approved Tenant Modifications

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

	 	
to the Shell, Core and Site Construction Documents. In no event shall the TI Allowance be used for the cost of demolition of any portion of the Premises previously improved using the TI
Allowance. Except during and to the extent of any active construction of any Tenant Improvements in the Premises pursuant to this Work Letter, all costs of power and other utilities used by Tenant constitute an Operating Expense under the Lease,
and, accordingly, shall not be a TI Cost and shall not be paid from the TI Allowance. Further, TI Costs do not include, and the TI Allowance shall not be used for, the following: furniture (except that the TI Allowance may be used for furniture in
the lobbies of the 75 Binney Building and the 125 Binney Building), audio visual, information technology (except that the TI Allowance may be used for the cost of IT installation, wiring, cabling and panels), scientific and other equipment to be
used in the Premises, and costs, including brokerage fees, in connection with any subletting of the Premises or any portion thereof or any assignment of this Lease. 

Landlord and Tenant confirm their agreement that certain TI Costs identified in Schedule 6.6 shall be funded and paid from the TI
Allowance, as follows: (i) preconstruction costs allocable to the Tenant Improvements; (ii) certain costs associated with the Tenant Delay in delivery of the 50% TI Construction Documents and 100% TI Construction Documents; and
(iii) TI Costs incurred to date. 
  

	6.7	Allocation of TI Costs. Landlord shall have no obligation to bear any portion of TI Costs except to the extent of the TI Allowance. As used in this Work Letter, “Landlord’s Portion” shall equal the
TI Allowance. For purposes of this Work Letter, “Landlord’s Proportionate Share” shall mean a fraction, the numerator of which shall be the Landlord’s Portion and the denominator of which shall be the anticipated TI Costs (as
reasonably determined by Landlord) for the Tenant Improvements (or applicable TI Phase). If at any time TI Costs under the Budget (or the Budget for the applicable TI Phase) exceed the TI Allowance, the difference shall be referred to herein as
“Tenant’s Portion.” For purposes of this Work Letter, “Tenant’s Proportionate Share” shall mean a fraction, the numerator of which is Tenant’s Portion and the denominator of which is the anticipated TI Costs (as
reasonably determined by Landlord). There shall be an adjustment of Landlord’s Proportionate Share and Tenant’s Proportionate Share from time to time based on changes in the anticipated TI Costs for the Tenant Improvements (or applicable
TI Phase). 

  

	6.8	Excess TI Costs. Landlord shall have no obligation to bear any portion of the cost of any of the Tenant Improvements except to the extent of the TI Allowance (and, in the case of a TI Phase, the allocable TI
Allowance therefor on a square footage basis). If at any time and from time-to-time, the remaining TI Costs under the Budget exceed the remaining unexpended TI Allowance, the calculation of Landlord’s Proportionate Share and Tenant’s
Proportionate Share of each monthly requisition shall be adjusted at that time, so that each party continues to bear its respective Proportionate Share of the remaining TI Costs under the adjusted Budget. For purposes of any enforcement action
instituted with regard to such amounts, those amounts will be deemed Rent under the Lease. 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

	6.9	Payment for TI Costs. During the course of design and construction of the Tenant Improvements, and subject to Section 6.8, each of Landlord and Tenant shall pay their respective Proportionate Share of
TI Costs (and shall provide to each other evidence of such payment) once a month against a draw request in Landlord’s standard form, containing such certifications, lien waivers (including a conditional lien release for each progress payment
and unconditional lien releases for the prior month’s progress payments), inspection reports and other matters as Landlord customarily obtains, to the extent of Landlord’s approval thereof for payment, within 30 days of receipt of such
draw request, so long as such draw request is submitted to, and approved by, Landlord by the 5th day of the month. Upon completion of the Tenant Improvements for the Tenant Improvements or any
phase thereof, Tenant shall deliver to Landlord: (i) sworn statements setting forth the names of all contractors and first tier subcontractors who did the work and final, unconditional lien waivers from all such contractors and first tier
subcontractors; (ii) as-built plans (two (2) copies in print format and one (1) copy in electronic CAD format) for such Tenant Improvements (or TI Phase); (iii) a certification of substantial completion in Form AIA G704,
(iv) a Certificate of Occupancy for the Premises (or temporary Certificate of Occupancy if for a portion of the Premises); and (v) copies of all operation and maintenance manuals and warranties affecting the Premises. 

 

	6.10	Test Fit Allowance. 

 Landlord has provided to Tenant a test fit allowance (“Test
Fit Allowance”) in the amount of $[***] per rentable square foot of the Premises (exclusive of the New Atrium Area) for third party design costs incurred by Tenant for the initial preparation of test fit drawings and revisions thereto for the
Tenant Improvements. Tenant acknowledges that the remaining balance of the Test Fit Allowance to which Tenant is entitled hereunder is the sum of $[***]. The Test Fit Allowance is in addition to the TI Allowance and the Additional TI Allowance. 

7 MISCELLANEOUS 
  

	7.1	Number; Headings 

 Where applicable in this Work Letter, the singular includes the
plural and the masculine or neuter includes the masculine, feminine and neuter. The section headings of this Work Letter are not a part of this Work Letter and shall have no effect upon the construction or interpretation of any part hereof. 

 

	7.2	Attorneys’ Fees  

 If either party commences an action against the other party
arising out of or in connection with this Work Letter, then the prevailing party shall be entitled to have and recover from the other party reasonable attorneys’ fees, charges and disbursements and costs of suit. 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

	7.3	Time of Essence 

 Time is of the essence with respect to the performance of every
provision of this Work Letter in which time of performance is a factor. 
  

	7.4	Withholding of Consent 

 Whenever consent or approval of either party is required, that
party shall not unreasonably withhold condition or delay such consent or approval, except as may be expressly set forth to the contrary. 
  

	7.5	Invalidity 

 Any provision of this Work Letter that shall prove to be invalid, void or
illegal shall in no way affect, impair or invalidate any other provision hereof, and all other provisions of this Work Letter shall remain in full force and effect and shall be interpreted as if the invalid, void or illegal provision did not exist.

  

	7.6	Interpretation 

 The language in all parts of this Work Letter shall be in all cases
construed as a whole according to its fair meaning and not strictly for or against either Landlord or Tenant. 
  

	7.7	Successors 

 Each of the covenants, conditions and agreements herein contained shall
inure to the benefit of and shall apply to and be binding upon the parties hereto and their respective heirs; legatees; devisees; executors; administrators; and permitted successors, assigns, sublessees. Nothing in this Section 7.7 shall
in any way alter the provisions of the Lease regarding assignment or subletting. 
  

	7.8	Governing Law 

 This Work Letter shall be governed by, construed and enforced in
accordance with the laws of the Commonwealth of Massachusetts, without regard to its conflict of law principles. 
  

	7.9	Power and Authority 

 Each of Tenant and Landlord guarantees, warrants and represents to
the other that the individual or individuals signing this Work Letter have the power, authority and legal capacity to sign this Work Letter on behalf of and to bind all entities, corporations, partnerships, limited liability companies, joint
venturers or other organizations and entities on whose behalf said individual or individuals have signed. 
  

	7.10	Counterparts 

 This Work Letter may be executed in one or more counterparts, each of
which, when taken together, shall constitute one and the same document. 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

	7.11	Amendments; Waiver  

 No provision of this Work Letter may be modified, amended or
supplemented except by an agreement in writing signed by Landlord and Tenant. The waiver by either party of any breach by the other party of any term, covenant or condition herein contained shall not be deemed to be a waiver of any subsequent breach
of the same or any other term, covenant or condition herein contained. 
  

	7.12	Dispute Process 

 Any dispute between Landlord and Tenant with respect to any matter
arising under this Work Letter shall be submitted first to the Landlord Representative and Tenant Representative named below for resolution. The initial Representatives of the parties shall be as follows, unless a party gives written notice to the
other party that it is replacing its Representative: 
  

			
	Landlord Representative:		Tom Andrews
		
	Tenant Representative:		Edward Fitzgerald

 The Landlord and Tenant Representatives shall meet one or more times to attempt to resolve such dispute within the 5-business
day period following the date that the dispute is submitted to them. If, after such meeting(s), the parties have been unable to resolve the dispute, either party may thereafter seek any available legal remedy, at law or in equity. 

 

	7.13	Waiver of Jury Trial 

 To the extent permitted by Applicable Laws, the parties waive
trial by jury in any action, proceeding or counterclaim brought by the other party hereto related to matters arising out of or in any way connected with this Work Letter. 
  

	7.14	Project Accounting 

 Landlord shall provide to Tenant (a) on a quarterly basis:
(i) an updated report as to certain costs of the Non-TI Project Improvements for the categories of expense identified in the attached Schedule 7.14 (collectively, “Reported Project Costs”), in the format attached hereto as
Schedule 7.14 [***]. Any Disclosed Documents so provided shall be subject to the following terms and conditions: 
  

	 	a)	Any Disclosed Documents provided to Tenant shall be used by Tenant only for the Special Permitted Use and for no other use. Specifically, the Disclosed Documents shall be used only to prepare the financial statements to
be disclosed publicly by Tenant and shall not themselves be disclosed to third parties, unless required solely for the purpose of the preparation or audit of such financial statements (the “Preparing/Auditing Parties”). 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

	 	b)	Any Disclosed Documents provided to Tenant shall be considered “Confidential Information” and Tenant shall not copy, duplicate, deliver, disclose or transmit the Disclosed Documents or their content to any
third party without Landlord’s express prior written approval, except to the Preparing/Auditing Parties solely for the purpose of the preparation or audit of such financial statements. 

 

	 	(c)	To the extent that any Disclosed Document will be prepared by a third party, such Disclosed Document will be prepared in accordance with a specific scope of work and maybe subject to specific limitations regarding its
use by third parties, including Tenant. 

  

	 	(d)	Neither Landlord nor any of its affiliates, employees, agents, successors or assigns (collectively, the “Landlord Parties”), nor any third party that prepared any Disclosed Document, has made or shall be
deemed to have made any representations, statements or warranties of any kind as to (i) the accuracy or validity of the information contained in any Disclosed Document; or (ii) the condition or cost of construction of the Project in any
respect as a consequence of providing the Disclosed Documents. 

  

	 	(e)	Tenant is responsible for making its own independent assessment and investigation of the condition and cost of construction of the Project. 

 

	 	(f)	To the extent permitted under applicable law, Tenant agrees to indemnify, defend and hold the Landlord Parties harmless from and against losses, costs, damages, claims or causes of action (including, without limitation,
any actions initiated by Tenant shareholders) arising out of any use of the Disclosed Information by Tenant or the Preparing/Auditing Parties, or their respective agents, employees or representatives, including, without limitation, the Special
Permitted Use and any use in violation of paragraphs (a) and (b) above. 

  

	 	(g)	Tenant, for itself and its agents, affiliates, successors and assigns, hereby releases and forever discharges each of the Landlord Parties from any and all rights, claims and demands at law or in equity, whether direct
or indirect, known or unknown, foreseen or unforeseen, at the time of this First Amendment, which Tenant has or may have in the future, arising out of the financial information provided by Landlord in the Disclosed Documents. With respect to the
waiver and release set forth herein relating to unknown and unsuspected claims, Tenant hereby acknowledges that such waiver and release is being made after obtaining the advice of counsel and with full knowledge and understanding of the consequences
and effects of such waiver. Nothing set forth herein shall in any way waive or limit any right or obligation of Landlord or of Tenant as otherwise set forth in the Lease which either party now has or may have in the future. 

[REMAINDER OF THIS PAGE INTENTIONALLY LEFT BLANK] 

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended. 

 IN WITNESS WHEREOF, Landlord and Tenant have executed this Work Letter to be effective on the
date first above written. 
  

									
	LANDLORD:
	
	 ARE-MA REGION NO. 48, LLC,
 a
Delaware limited liability company

			
			By:		Alexandria Real Estate Equities, L.P., a Delaware limited partnership, its managing member
				
					By:		ARE-QRS Corp.,
							a Maryland corporation, its general partner
					
							By:		 /s/ Eric Johnson

							Name:		 Eric Johnson

							Title:		 Senior Vice President, RE Legal Affairs

	
	TENANT:
	
	 ARIAD Pharmaceuticals, Inc.,
 a
Delaware corporation

		
	By:		 /s/ Edward M. Fitzgerald

	Name:		 Edward M. Fitzgerald

	Title:		 Executive Vice President, CFO

			Hereunto Duly Authorized

  
 Portions of this Exhibit, indicated
by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities
Exchange Act of 1934, as amended.EX-10.1

 Exhibit 10.1 

EMPLOYEE MATTERS AGREEMENT 

This EMPLOYEE MATTERS AGREEMENT is made as of             , 2015 by and between
NiSource Inc., a Delaware corporation (“NiSource”), and Columbia Pipeline Group, Inc., a Delaware corporation (“Columbia”), and, as of the date hereof, a wholly-owned subsidiary of NiSource. 

WHEREAS, NiSource and Columbia have entered into a Separation and Distribution Agreement dated as of the date hereof (the
“Distribution Agreement”) pursuant to which NiSource will distribute on a pro rata basis to the holders of shares of NiSource common stock, par value $0.01 per share (“NiSource Shares”), without
any consideration being paid by the holders of such NiSource Shares, all of the outstanding shares of Columbia common stock, par value $0.01 per share (“Columbia Shares”), owned by NiSource as of the Distribution Date (as
defined in the Distribution Agreement); and 
 WHEREAS, in connection with the Distribution (as defined in the Distribution Agreement),
NiSource and Columbia desire to enter into this Employee Matters Agreement. 
 NOW, THEREFORE, in consideration of the mutual promises
contained herein and in the Distribution Agreement, the parties hereto agree as follows: 
 ARTICLE I 

DEFINITIONS 
 1.01
Definitions. Unless otherwise defined herein, each capitalized term shall have the meaning specified for such term in the Distribution Agreement. As used in this Agreement: 

“Adjusted NiSource Phantom Stock Unit Award” has the meaning set forth in Section 6.04(b). 

“Adjusted NiSource RSU Award” has the meaning set forth in Section 6.02(b). 

“Agreement” means this Employee Matters Agreement together with those parts of the Distribution Agreement referenced
herein and all schedules hereto and all amendments, modifications and changes hereto and thereto. 
 “Business
Employee” means (i) each individual who immediately prior to the Distribution Date is employed by a Columbia Party, including each Transferred Employee, and (ii) each former employee of a NiSource Party, a Columbia Party or a
Former Business owned, in whole or in part, by any of the Columbia Parties whose last employment with any of such parties prior to termination (before the Distribution Date) was with a Columbia Party or a Former Business owned, in whole or in part,
by any of the Columbia Parties. 
 “CIP Award” has the meaning set forth in Section 5.02. 

“Code” means the Internal Revenue Code of 1986. 

 “Columbia” has the meaning set forth in the first paragraph of this
Agreement. 
 “Columbia Deferred Compensation Plans” has the meaning set forth in Section 3.03. 

“Columbia Employee” means a person who is employed by a Columbia Party immediately following the Distribution Date.

 “Columbia ESPP” has the meaning set forth in Section 6.05(a). 

“Columbia FSA” has the meaning set forth in Section 4.05. 

“Columbia Life and Medical VEBA Trusts” mean the Non-Union Life and Medical Benefits VEBA Trust and the Union Life and
Medical Benefits VEBA Trust adopted by the Columbia Parties on or prior to the Distribution Date. 
 “Columbia Pension
Plan” has the meaning set forth in Section 3.02(a). 
 “Columbia Pension Trust” has the meaning set
forth in Section 3.02(b). 
 “Columbia Post-Distribution Stock Price” means the per share price of Columbia Shares,
which shall be equal to the average of the volume weighted average price of Columbia Shares, traded on a when-issued basis, for each of the three consecutive trading days immediately preceding the Distribution Date. 

“Columbia Post-65 Retiree Medical VEBA Trusts” mean the Non-Union Post-65 Retiree Medical Benefits VEBA Trust and the
Union Post-65 Retiree Medical Benefits VEBA Trust adopted by the Columbia Parties on or prior to the Distribution Date. 

“Columbia Rabbi Trusts” has the meaning set forth in Section 3.03. 

“Columbia Retiree Welfare Plans” has the meaning set forth in Section 4.06(a). 

“Columbia RSP” has the meaning set forth in Section 3.01(a). 

“Columbia RSP Trust” means the trust maintained under the Columbia RSP. 

“Columbia Shares” has the meaning set forth in the recitals of this Agreement. 

“Columbia Stock Plans” has the meaning set forth in Section 6.01. 

“Columbia Welfare Plan” has the meaning set forth in Section 4.01. 

“Compensation Committee” means the Officer Nomination and Compensation Committee of the NiSource Board or the Human
Resources and Compensation Committee of the Columbia Board, as the case may be. 
 “Deceased Business Employee”
means an individual who died prior to the Distribution Date while (i) an employee of a Columbia Party or (ii) a retiree (or for purposes of Article III only, a former employee of a NiSource Party, a Columbia Party or a Former Business
owned, in whole or in part, by any of the Columbia Parties) whose last employment prior to termination was with a Columbia Party or with a Former Business owned, in whole or in part, by any of the Columbia Parties. 

  
 2 

 “Distribution Agreement” has the meaning set forth in the recitals of
this Agreement. 
 “ERISA” means the Employee Retirement Income Security Act of 1974. 

“Final Transfer Amount” has the meaning set forth in Section 3.02(b). 

“Final Transfer Date” has the meaning set forth in Section 3.02(b). 

“Former Columbia Directors” has the meaning set forth in Section 7.02(f). 

“Initial Transfer Amount” has the meaning set forth in Section 3.02(b). 

“IRS” means the Internal Revenue Service. 

“NiSource” has the meaning set forth in the first paragraph of this Agreement. 

“NiSource DB Master Trust” has the meaning set forth in Section 3.02(b). 

“NiSource Deferred Compensation Plans” mean the NiSource Inc. Executive Deferred Compensation Plan, the Savings
Restoration Plan for NiSource Inc. and Affiliates and the Pension Restoration Plan for NiSource Inc. and Affiliates. 
 “NiSource
ESPP” has the meaning set forth in Section 6.05(a). 
 “NiSource FSA” has the meaning set forth in
Section 4.05. 
 “NiSource Life and Medical VEBA Trusts” mean the NiSource Non-Union Life and Medical Benefits VEBA
Trust and the NiSource Union Life and Medical Benefits VEBA Trust. 
 “NiSource Non-ERISA Benefit Arrangement” means
any Non-ERISA Benefit Arrangement sponsored or maintained by a NiSource Party. 
 “NiSource Pension Plans” mean the
Columbia Energy Group Pension Plan and the NiSource Salaried Pension Plan. 
 “NiSource Performance Share Award”
means a performance share award granted under any of the NiSource Stock Plans that is outstanding as of the Distribution Date. 

“NiSource Phantom Stock Unit Award” means a phantom stock unit award granted to certain executives following the
acquisition of Columbia Energy Group by NiSource, as part of agreements entered into as of February 1, 2001, that is outstanding as of the Distribution Date. 

“NiSource Plan” means any Pension Plan or Welfare Plan sponsored or maintained by a NiSource Party. 

“NiSource Post-65 Retiree Medical VEBA Trusts” mean the NiSource Non-Union Post-65 Retiree Medical Benefits VEBA Trust
and the NiSource Union Post-65 Retiree Medical Benefits VEBA Trust. 

  
 3 

 “NiSource Post-Distribution Stock Price” means the per share price of
NiSource Shares, determined on a post-Distribution basis, which shall be equal to the average of the volume weighted average price of NiSource Shares, traded on a when-issued basis, for each of the three consecutive trading days immediately
preceding the Distribution Date. 
 “NiSource Pre-Distribution Stock Price” means the per share price of NiSource
Shares, determined on a pre-Distribution basis, which shall be equal to the average of the volume weighted average price of NiSource Shares, traded with due bills, for each of the three consecutive trading days immediately preceding the Distribution
Date. 
 “NiSource Rabbi Trusts” has the meaning set forth in Section 3.03. 

“NiSource Retiree Welfare Plans” mean the retiree Welfare Plans sponsored or maintained by a NiSource Party, including
the NiSource Consolidated Flex Medical Plan, the NiSource Post-65 Retiree Medical Plan and the NiSource Life Insurance Plan. 

“NiSource RSP” means the NiSource Inc. Retirement Savings Plan. 

“NiSource RSP Trust” means the trust maintained under the NiSource RSP. 

“NiSource RSU Award” means a restricted stock unit award granted under any of the NiSource Stock Plans that is
outstanding as of the Distribution Date. 
 “NiSource Shares” has the meaning set forth in the recitals of this
Agreement. 
 “NiSource Stock Plans” mean the NiSource Inc. 2010 Omnibus Incentive Plan and the NiSource Inc.
Nonemployee Director Stock Incentive Plan. 
 “NiSource Welfare Plan” means a Welfare Plan sponsored or maintained
by a NiSource Party. 
 “Non-ERISA Benefit Arrangement” means any contract, agreement, policy, practice, program,
plan, trust or arrangement, other than a Pension Plan or Welfare Plan, providing for benefits, perquisites or compensation of any nature, including but not limited to tuition reimbursement, adoption assistance, vacation, holidays, sick, personal or
bereavement days, relocation benefits, supplemental unemployment, bonus or other forms of incentive compensation. 
 “Pension
Plan” means any pension plan as defined in Section 3(2) of ERISA, without regard to Section 4(b)(4) or 4(b)(5) of ERISA. 

“Substitute Columbia Phantom Stock Unit Award” has the meaning set forth in Section 6.04(a). 

“Substitute Columbia RSU Award” has the meaning set forth in Section 6.02(a). 

“Surviving Dependent” means each individual who immediately prior to the Distribution Date was enrolled in the
NiSource Consolidated Flex Medical Plan or NiSource Post-65 Retiree Medical Plan as a surviving dependent of a Deceased Business Employee. 

  
 4 

 “Transferred Employee” means each employee of a NiSource Party or any of
its Affiliates (other than Columbia or any Columbia Subsidiary) whose employment shall have been transferred from a NiSource Party to a Columbia Party prior to the Distribution Date. 

“VEBA” means a tax-exempt entity established pursuant to Section 501(c)(9) of the Code. 

“Welfare Plan” means any employee welfare plan as defined in Section 3(1) of ERISA, without regard to
Section 4(b)(4) or 4(b)(5) of ERISA. 
 1.02 Rules of Construction. 

(a) For purposes of this Agreement: 

(1) the words “include,” “includes” and “including” shall be deemed to be followed by the words
“without limitation;” 
 (2) the word “or” is not exclusive; 

(3) the words “herein,” “hereunder,” “hereof,” “hereby,” “hereto” and words
of similar import shall be deemed to be references to this Agreement as a whole and not to any particular Section or other provision hereof; and 

(4) relative to the determination of any period of time, “from” means “from and including,” “to”
means “to but excluding” and “through” means “through and including.” 
 (b) In this Agreement,
unless the context clearly indicates otherwise: 
 (1) words used in the singular include the plural and words used in the
plural include the singular; 
 (2) reference to any Person includes such Person’s successors and assigns but, if
applicable, only if such successors and assigns are permitted by this Agreement; 
 (3) reference to any Person’s
“Affiliates” shall be deemed to mean such Person’s Affiliates following the Distribution; 
 (4) reference to
any gender includes the other gender and the neutral gender; 
 (5) reference to any Article, Section or Exhibit means such
Article or Section of, or such Exhibit to, this Agreement, as the case may be; 
 (6) reference to any agreement, instrument
or other document means such agreement, instrument or other document as amended, supplemented and modified from time to time to the extent permitted by the provisions thereof and by this Agreement; 

  
 5 

 (7) reference to any Law (including statutes and ordinances) means such Law
(including all rules and regulations promulgated thereunder) as amended, modified, codified or reenacted, in whole or in part, and in effect at the time of determining compliance or applicability; 

(8) accounting terms used herein shall have the meanings ascribed to them by NiSource and its Subsidiaries, including Columbia,
in its and their internal accounting and financial policies and procedures in effect immediately prior to the date of this Agreement; 

(9) if there is any conflict between the provisions of the Distribution Agreement and this Agreement, the provisions of this
Agreement shall control with respect to the subject matter hereof; 
 (10) any portion of this Agreement obligating a party
hereto to take any action or refrain from taking any action, as the case may be, shall mean that such party shall also be obligated to cause its relevant Subsidiaries to take such action or refrain from taking such action, as the case may be; and

 (11) all references to dollar amounts shall be in respect of lawful currency of the United States. 

(c) The titles to Articles and headings of Sections contained in this Agreement have been inserted for convenience of reference
only and shall not be deemed to be a part of or to affect the meaning or interpretation of this Agreement, and this Agreement and the Transaction Agreements shall be construed without regard to any presumption or rule requiring construction or
interpretation against the party drafting an instrument or causing any instrument to be drafted. 
 (d) The Exhibit shall be
construed with and as an integral part of this Agreement to the same extent as if the same had been set forth verbatim herein. 
 ARTICLE
II 
 ASSIGNMENT OF EMPLOYEES 

As of the date immediately prior to the Distribution Date, the employment of the Transferred Employees by the NiSource Parties shall have
terminated and been assigned and transferred to a Columbia Party. Notwithstanding anything to the contrary contained herein, nothing in this Agreement shall create any obligation on the part of any Columbia Party to continue the employment of any
employee for any definite period following the Distribution Date or to change the employment status of any employee from “at will.” 

  
 6 

 ARTICLE III 

PENSION, RETIREMENT AND DEFERRED COMPENSATION PLANS 

3.01 Defined Contribution Plans. 

(a) Establishment of the Columbia Retirement Savings Plan. Effective on or before the Distribution Date, Columbia shall
adopt, establish and maintain a 401(k) profit sharing plan and trust for the benefit of employees of the Columbia Parties that is substantially similar to the NiSource RSP and is intended to be qualified under Section 401(a) of the Code and
exempt from federal income tax under Section 501(a) of the Code (the “Columbia RSP”). As soon as practicable after the adoption of the Columbia RSP, or as otherwise required under Revenue Procedure 2007-44, Columbia
shall submit an application to the IRS for a determination that the Columbia RSP is qualified under Section 401(a) of the Code and that the related Columbia RSP Trust is exempt from federal income tax under Section 501(a) of the Code, and
shall take any actions not inconsistent with Columbia’s other general commitments contained in this Agreement and make any amendments necessary to receive such determination. As of the Distribution Date, each Business Employee employed by the
Columbia Parties (and any survivor or beneficiary of a Deceased Business Employee who is entitled to a benefit under the NiSource RSP immediately prior to the Distribution Date) shall be eligible to participate in the Columbia RSP, which shall
recognize the service of such Business Employee with NiSource and its Subsidiaries in accordance with Section 7.04. 

(b) Transfer of Assets from NiSource, Inc. Retirement Savings Plan. On or as soon as administratively practicable after
the Distribution Date, NiSource shall cause the NiSource RSP Trust to transfer to the Columbia RSP Trust assets having a value as of the applicable valuation date that is equal to the value of the account balances of, and accrued liabilities
(including any outstanding loan balances) with respect to, all Business Employees and all survivors and beneficiaries of all Deceased Business Employees with an account balance under the NiSource RSP as of such valuation date. “Accrued
liabilities” for these purposes shall include employer matching contributions and nondiscretionary employer profit sharing contributions deposited to the NiSource RSP Trust on a per payroll basis for any Business Employee that was accrued prior
to the transfer of assets from the NiSource RSP Trust to the Columbia RSP Trust. Notwithstanding the foregoing, with respect to any discretionary profit sharing contributions payable to Business Employees for the 2015 calendar year and to be paid
after the end of the 2015 calendar year, (i) NiSource and Columbia shall determine the amount of any employer profit sharing contribution, including the identification of Business Employees who satisfy the eligibility requirements for such
profit sharing contribution under the Columbia RSP as of December 31, 2015 and who would have satisfied such requirements under the NiSource RSP but for the Distribution, (ii) NiSource shall make a cash payment to Columbia equal to the
portion of such contribution that is associated with service for and compensation earned prior to the date of the Distribution, with such payment to be made on or before the due date for such contribution under the terms of the Code and the Columbia
RSP and (iii) Columbia shall contribute to the Columbia RSP the full amount of such contribution. Columbia shall be solely responsible for and shall determine the amount of any discretionary profit sharing contribution payable to these Business
Employees that is associated with service for and compensation earned from Columbia or an Affiliate for the period beginning on the Distribution Date and ending on December 31, 2015. In addition, on or as soon as administratively practicable
after the Distribution Date, a pro rata share of all unallocated amounts (including but not limited to any forfeiture accounts, revenue sharing credit accounts or other unallocated accounts held under the NiSource RSP immediately prior to

  
 7 

 
the Distribution Date) shall be transferred from the NiSource RSP Trust to the Columbia RSP Trust, determined based upon the ratio of the number of all Business Employees actively participating
in the NiSource RSP immediately prior to the Distribution Date to the number of all employees actively participating in the NiSource RSP immediately prior to the Distribution Date. Assets transferred pursuant to this paragraph shall be in cash or in
kind, including shares of securities, promissory notes evidencing outstanding plan loans, NiSource Shares or Columbia Shares, and such transfer shall be made in accordance with Section 414(l) of the Code. Liabilities under any qualified
domestic relations orders (as defined in Section 414(p) of the Code) received with respect to any accounts transferred to the Columbia RSP shall be transferred to and assumed by the Columbia RSP at the time such assets attributable to such
accounts are transferred. NiSource shall transfer to Columbia, and Columbia shall accept any promissory notes, including outstanding loan balances, of Business Employees in the NiSource RSP, and Columbia shall continue to process any plan loans
transferred from the NiSource RSP to the Columbia RSP. All beneficiary designations made by Business Employees and by survivors and beneficiaries of Deceased Business Employees under the NiSource RSP shall, to the extent applicable, be transferred
to, and be in full force and effect under, the Columbia RSP until such beneficiary designations are subsequently replaced or revoked by the Business Employee (or the survivor or beneficiary of the Deceased Business Employee) who made the beneficiary
designation (or his legally recognized agent). Except as noted above with respect to profit sharing contribution liabilities relating to 2015, on and after the Distribution Date, Columbia shall assume and thereafter be solely responsible for all
then existing and future employer liabilities related to such Business Employees and survivors and beneficiaries of Deceased Business Employees under the Columbia RSP and the administration thereof and the NiSource Parties shall have no liability
whatsoever therefor. 
 (c) Liquidation of Company Stock Funds. Subject to the fiduciary and other requirements of
ERISA, and any other applicable Laws, NiSource shall take such actions as are reasonably necessary to ensure that any liquidation of Columbia Shares held in the NiSource RSP after the Distribution Date is orderly and periodic. Subject to the
exercise of its fiduciary duties or other requirements of ERISA and any other applicable Laws, as soon as administratively practicable after the Distribution Date, NiSource shall permit participants in the NiSource RSP to transfer the investment of
their plan accounts out of the Columbia Share fund maintained under such plan and shall prohibit participants from transferring the investment of their plan accounts or electing the investment of new contributions into such Columbia Share fund, but
shall not otherwise require the liquidation of any Columbia Shares from the NiSource RSP until the first anniversary of the Distribution Date or other such date determined by the NiSource Benefits Committee as the named fiduciary for the NiSource
RSP. Notwithstanding the foregoing, nothing herein shall require the liquidation of Columbia Shares from the NiSource RSP. Subject to the fiduciary and other requirements of ERISA, and any other applicable Laws, Columbia shall take such actions as
are reasonably necessary to ensure that any liquidation of NiSource Shares held in the Columbia RSP is orderly and periodic. Subject to the exercise of its fiduciary duties or other requirements of ERISA and any other applicable Laws, as soon as
administratively practicable after the Distribution Date, Columbia shall permit participants in the Columbia RSP to transfer the investment of their plan accounts out of the NiSource Share 

  
 8 

 
fund maintained under such plan and shall prohibit participants from transferring the investment of their plan accounts or electing the investment of new contributions into such NiSource Share
fund, but shall not otherwise require the liquidation of any NiSource Shares from the Columbia RSP until the first anniversary of the Distribution Date or other such date determined by the named fiduciary for the Columbia RSP. Notwithstanding the
foregoing, nothing herein shall require the liquidation of NiSource Shares from the Columbia RSP. 
 3.02 Defined Benefit Pension
Plans.  
 (a) Establishment of Columbia Pension Plan. Effective on or before the Distribution Date,
Columbia shall adopt, establish and maintain a Pension Plan and a trust for the benefit of employees of the Columbia Parties (the “Columbia Pension Plan”). Whether in a unified plan document or multiple plan documents that
make up a single Pension Plan, the Columbia Pension Plan will be substantially similar to each applicable NiSource Pension Plan that has a portion of assets and liabilities transferred pursuant to Section 3.02(b), and to the related trust(s).
The Columbia Pension Plan is intended to be qualified under Section 401(a) of the Code and exempt from federal income tax under Section 501(a) of the Code. As soon as practicable after the adoption of the Columbia Pension Plan and trust,
or as otherwise required under Revenue Procedure 2007-44, Columbia shall submit an application to the IRS for a determination that the Columbia Pension Plan is qualified under Section 401(a) of the Code and that the related trust is exempt from
federal income tax under Section 501(a) of the Code, and shall take any actions not inconsistent with Columbia’s other general commitments contained in this Agreement and make any amendments necessary to receive such determination. 

(b) Transfer of Assets and Liabilities. As of the Distribution Date, the Columbia Pension Plan shall assume all
liabilities with respect to all Business Employees under the NiSource Pension Plans (and any survivor or beneficiary of a Deceased Business Employee who is entitled to a benefit under the NiSource Pension Plans immediately prior to the Distribution
Date) and neither NiSource nor any of its Affiliates shall retain any such liabilities. On the Distribution Date, NiSource shall cause to be transferred from the NiSource Master Retirement Trust (the “NiSource DB Master
Trust”) to the trust established for the Columbia Pension Plan (the “Columbia Pension Trust”) an initial amount of assets (the “Initial Transfer Amount”) in funds that are immediately
available funds under the NiSource DB Master Trust, which such amount shall be equal to 75% of the amount the actuary engaged by the NiSource Pension Plans determines in good faith to be a reasonable estimate of the amount of assets to be
transferred as of the Distribution Date for all Business Employees (and all survivors and beneficiaries of Deceased Business Employees) with accrued benefits under the NiSource Pension Plans in accordance with Section 414(l) of the Code and
Section 4044 of ERISA. As soon as administratively practicable after the Distribution Date, the actuary engaged by the NiSource Pension Plans shall determine the final amount of assets to be transferred as of the Distribution Date for all
Business Employees (and all survivors and beneficiaries of Deceased Business Employees) with accrued benefits under the NiSource Pension Plans in accordance with Section 414(l) of the Code and Section 4044 of ERISA (the “Final
Transfer Amount”). As soon as administratively practicable after the later 

  
 9 

 
to occur of (i) the date the Final Transfer Amount is determined and (ii) the expiration of the waiting period prescribed by Section 6058(b) of the Code, the NiSource Parties shall
direct the trustee of the NiSource DB Master Trust to transfer the Final Transfer Amount in funds that are immediately available funds under the NiSource DB Master Trust to the trustee of the Columbia Pension Trust. The Final Transfer Amount
shall be reduced (i) by the Initial Transfer Amount, (ii) as necessary to reflect benefit payments made from the NiSource DB Master Trust on behalf of any Business Employees (or any survivors or beneficiaries of Deceased Business
Employees), which such payments are effective as of the Distribution Date or any other date between the Distribution Date and the Final Transfer Date, (iii) by any administrative expenses paid from the NiSource DB Master Trust prior to the
Final Transfer Date in preparation for the administration of the Columbia Pension Plan and the transfer of the Final Transfer Amount to the Columbia Pension Trust and (iv) by the pro-rata portion of monthly investment expenses incurred by the
NiSource Pension Plans attributable to the Final Transfer Amount for the period beginning on the Distribution Date and ending on the Final Transfer Date. From the actual date of delivery of the Initial Transfer Amount on the Distribution Date until
the actual date of delivery of the Final Transfer Amount (the “Final Transfer Date”), the trustee of the NiSource DB Master Trust shall hold the Final Transfer Amount under the NiSource Pension Plans and the Final Transfer
Amount shall be credited with earnings, from the Distribution Date to the Final Transfer Date, at a rate equal to the actual rate of return for the investments in the NiSource DB Master Trust for the period beginning on the Distribution Date and
ending on the Final Transfer Date. Further, liabilities under any qualified domestic relations orders (as defined in Section 414(p) of the Code) received with regard to any benefits for such Business Employees shall be transferred to and
assumed by the Columbia Pension Plan as of the Distribution Date. All beneficiary designations made by Business Employees and by survivors and beneficiaries of Deceased Business Employees under the NiSource Pension Plans shall, to the extent
applicable, be transferred to, and be in full force and effect under, the Columbia Pension Plan until such beneficiary designations are replaced or revoked by the Business Employee (or the survivor or beneficiary of the Deceased Business Employee)
who made the beneficiary designation (or his legally recognized agent). 
 3.03 Nonqualified Deferred Compensation Plans. Effective
on or before the Distribution Date, Columbia shall adopt, establish and maintain nonqualified deferred compensation plans for the benefit of employees of the Columbia Parties (the “Columbia Deferred Compensation Plans”) and
shall establish one or more grantor trusts to be a source of providing benefits thereunder (the “Columbia Rabbi Trusts”) that in each case shall be substantially similar to the NiSource Deferred Compensation Plans and the
grantor trusts maintained by NiSource with respect to the NiSource Deferred Compensation Plans (the “NiSource Rabbi Trusts”). As of the Distribution Date, the Columbia Parties shall assume and thereafter be solely responsible
for all existing and future liabilities relating to Business Employees’ (and Deceased Business Employee survivors’ and beneficiaries’) (a) benefits accrued under the NiSource Deferred Compensation Plans prior to the Distribution
Date and (b) benefits that accrue under the Columbia Deferred Compensation Plans on and after the Distribution Date. All beneficiary designations made by Business Employees and by survivors and beneficiaries of Deceased Business Employees under
the NiSource Deferred Compensation Plans shall, to the extent applicable, be transferred to, and be in full force and effect under, the Columbia Deferred Compensation Plans until such beneficiary designations are replaced or revoked by the Business

  
 10 

 
Employee (or the survivor or beneficiary of the Deceased Business Employee) who made the beneficiary designation. Following the Distribution Date, the NiSource Parties shall have no liability or
obligation with respect to the benefits accrued by such Business Employees or by such survivors or beneficiaries of Deceased Business Employees under any of the NiSource Deferred Compensation Plans or with respect to any benefits accrued under the
Columbia Deferred Compensation Plans. As soon as administratively practicable after the Distribution Date, NiSource shall cause the NiSource Rabbi Trusts to transfer to the Columbia Rabbi Trusts cash, life insurance policies or other assets having
an aggregate fair market value equal to (i) the aggregate fair market value of all assets held in the NiSource Rabbi Trusts as of the Distribution Date multiplied by (ii) a percentage, the numerator of which shall be the lump sum present
value of the benefits assumed by the Columbia Deferred Compensation Plans pursuant to this Section 3.03 and the denominator of which shall be the lump sum present value of all benefits accrued under the NiSource Deferred Compensation Plans
immediately prior to the Distribution Date. 
 ARTICLE IV 

WELFARE PLANS 
 4.01
Establishment of the Columbia Welfare Plans. Effective on or before the Distribution Date, Columbia shall adopt, establish and maintain Welfare Plans for the benefit of employees of the Columbia Parties that are substantially similar to the
NiSource Welfare Plans (the “Columbia Welfare Plans”). 
 4.02 Coverage of Business Employees and Surviving
Dependents. As of the Distribution Date, each Business Employee shall become eligible to participate in the Columbia Welfare Plans and each Surviving Dependent shall become eligible to participate in the Columbia Pipeline Group Consolidated Flex
Medical Plan, subject to the terms of such plans. To the extent applicable to any Columbia Welfare Plans in which Business Employees or Surviving Dependents become eligible as of the Distribution Date that provide benefits similar to the benefits
that had been provided to such persons under a NiSource Welfare Plan immediately prior to such date, Columbia shall cause the Columbia Welfare Plans to recognize all coverage and contribution elections made by the Business Employees and Surviving
Dependents under the NiSource Welfare Plans in effect for the period immediately prior to the Distribution Date and shall apply such elections under the Columbia Welfare Plans for the remainder of the period or periods for which such elections are
by their terms applicable. All beneficiary designations made by Business Employees and Surviving Dependents under the NiSource Welfare Plans shall, to the extent applicable, be transferred to, and be in full force and effect under, the Columbia
Welfare Plans until such beneficiary designations are replaced or revoked by the Business Employee or Surviving Dependent who made the beneficiary designation. With respect to each Business Employee and Surviving Dependent, each Columbia Welfare
Plan shall provide that for purposes of determining eligibility to participate, vesting and calculation of, and entitlement to, benefits, service by the Business Employee or, in the case of a Surviving Dependent, the Deceased Business Employee,
prior to the Distribution Date with a NiSource Party shall be treated as service with a Columbia Party. Columbia shall cause each Columbia Welfare Plan to waive any waiting periods, evidence of insurability requirements, and the application of any
preexisting condition limitations with respect to each Business Employee (and, if applicable, such Business Employee’s participating spouse and/or dependents) and Surviving Dependent. Columbia shall cause each Columbia Welfare Plan to honor any
deductible, co-payment and out-of-pocket 

  
 11 

 
maximums incurred by each Business Employee (and, if applicable, such Business Employee’s participating spouse and/or dependents) and Surviving Dependent under the NiSource Welfare Plans in
which such Business Employee or Surviving Dependent participated immediately prior to the Distribution Date, if any, in satisfying any deductibles, co-payments or out-of-pocket maximums under the Columbia Welfare Plans in which such Business
Employee or Surviving Dependent is eligible to participate after the Distribution Date in the same plan year in which any such deductibles, co-payments or out-of-pocket maximums were incurred. All amounts credited or applied to any annual or
lifetime benefit limitation under a NiSource Welfare Plan with respect to a Business Employee (and, if applicable, such Business Employee’s participating spouse and/or dependents) or Surviving Dependent shall be credited or applied to the
annual or lifetime benefit limitation for such Business Employee (and, if applicable, such Business Employee’s participating spouse and/or dependents) or Surviving Dependent under the corresponding Columbia Welfare Plan. 

4.03 Welfare Plan Liabilities. 

(a) Columbia Liabilities. Except as provided in clause (b) of this Section 4.03, the Columbia Parties and the
Columbia Welfare Plans, as applicable, shall retain and be responsible for all claims for welfare benefits (and for any Liabilities arising as a result of such claims) incurred with respect to any Business Employee (and, if applicable, such Business
Employee’s participating spouse and/or dependents) or Surviving Dependent on or after the Distribution Date under the Columbia Welfare Plans, and none of the NiSource Parties nor the NiSource Welfare Plans shall assume or retain any such
Liabilities. 
 (b) NiSource Liabilities. Except as provided in Section 4.05, NiSource and the NiSource Welfare
Plans shall continue to be responsible for all claims for welfare benefits (and for any Liabilities arising as a result of such claims) incurred with respect to any Business Employee (and, if applicable, such Business Employee’s participating
spouse and/or dependents) or Surviving Dependent prior to the Distribution Date (except with respect to any claims for long-term or short-term disability benefits due and payable on and after the Distribution Date, but incurred prior to the
Distribution Date), whether such claims have been paid or remain unpaid as of such date, and neither Columbia nor the Columbia Welfare Plans shall assume or retain any such Liabilities. 

(c) Claims Incurred. Claims for group health plan benefits shall be considered to be incurred prior to the Distribution
Date if the services related to such claims were provided prior to the Distribution Date. Claims for all other welfare benefits shall be considered to be incurred prior to the Distribution Date if the date of loss occurred prior to the Distribution
Date. 
 4.04 COBRA and HIPAA Liabilities. From and after the Distribution Date, the Columbia Parties and the Columbia Welfare Plans
shall be responsible for the continuation coverage requirements under the Consolidated Omnibus Budget Reconciliation Act of 1985 and the portability requirements under the Health Insurance Portability and Accountability Act of 1996 with respect to
all Business Employees and their qualified beneficiaries. 

  
 12 

 4.05 Flexible Spending Accounts. As of the Distribution Date, each Business Employee shall
become eligible to participate in a flexible spending account plan established by Columbia (the “Columbia FSA”), subject to the terms of such plan. Effective as of the Distribution Date, the Columbia FSA shall credit or debit
the applicable account of each Business Employee who, as of the Distribution Date, was a participant in the flexible spending account plan maintained by NiSource (the “NiSource FSA”), with an amount equal to the balance of
his or her account under the NiSource FSA as of the Distribution Date, and shall continue his or her elections thereunder. If the claims made against a Business Employee’s NiSource FSA account prior to the Distribution Date exceed the amounts
credited to such account at the Distribution Date, Columbia shall reimburse NiSource for the amount of such difference. If the amounts credited to a Business Employee’s NiSource FSA account at the Distribution Date exceed the claims made
against such account prior to the Distribution Date, NiSource shall reimburse Columbia for the amount of such difference. The Columbia FSA shall assume responsibility as of the Distribution Date for all outstanding dependent care and medical care
claims under the NiSource FSA of each Business Employee and shall assume and perform the obligations from and after the Distribution Date. From and after the Distribution Date, NiSource shall provide Columbia with such information Columbia may
reasonably request to enable it to verify any claims information pertaining to the NiSource FSA. 
 4.06 Retiree Welfare Plans. 

(a) Columbia Retiree Welfare Plans. Effective on or before the Distribution Date, Columbia shall adopt, establish and
maintain retiree Welfare Plans that are substantially similar to the NiSource Retiree Welfare Plans (the “Columbia Retiree Welfare Plans”). 

(b) Coverage of Business Employees and Surviving Dependents. As of the Distribution Date, each Business Employee shall
become eligible to participate in the Columbia Retiree Welfare Plans established by Columbia and each Surviving Dependent shall become eligible to participate in the Columbia Pipeline Group Consolidated Flex Medical Plan and the Columbia Pipeline
Group Post-65 Retiree Medical Plan, subject to the terms of such plans. To the extent applicable to any Columbia Retiree Welfare Plans in which Business Employees or Surviving Dependents become eligible as of the Distribution Date that provide
benefits similar to the benefits that had been provided to such persons under a NiSource Retiree Welfare Plan immediately prior to such date, Columbia shall cause the Columbia Retiree Welfare Plans to recognize all coverage and contribution
elections made by the Business Employees and Surviving Dependents under the NiSource Retiree Welfare Plans in effect for the period immediately prior to the Distribution Date and shall apply such elections under the Columbia Retiree Welfare Plans
for the remainder of the period or periods for which such elections are by their terms applicable. All beneficiary designations made by Business Employees and Surviving Dependents under the NiSource Retiree Welfare Plans shall, to the extent
applicable, be transferred to, and be in full force and effect under, the Columbia Retiree Welfare Plans until such beneficiary designations are replaced or revoked by the Business Employee or Surviving Dependent who made the beneficiary
designation. With respect to each Business Employee and Surviving Dependent, each Columbia Retiree Welfare Plan shall provide that for purposes of determining eligibility to participate, vesting and entitlement to benefits, service by the Business
Employee or, 

  
 13 

 
in the case of a Surviving Dependent, the Deceased Business Employee, prior to the Distribution Date with a NiSource Party shall be treated as service with a Columbia Party. Columbia shall cause
each Columbia Retiree Welfare Plan to waive any waiting periods, evidence of insurability requirements, and the application of any preexisting condition limitations with respect to each Business Employee (and, if applicable, such Business
Employee’s participating spouse and/or dependents) and Surviving Dependent. Columbia shall cause each Columbia Retiree Welfare Plan to honor any deductible, co-payment and out-of-pocket maximums incurred by each Business Employee (and, if
applicable, such Business Employee’s participating spouse and/or dependents) and Surviving Dependent under the NiSource Retiree Welfare Plans in which such Business Employee or Surviving Dependent participated immediately prior to the
Distribution Date, if any, in satisfying any deductibles, co-payments or out-of-pocket maximums under the Columbia Retiree Welfare Plans in which such Business Employee or Surviving Dependent is eligible to participate after the Distribution Date in
the same plan year in which any such deductibles, co-payments or out-of-pocket maximums were incurred. All amounts credited or applied to any annual or lifetime benefit limitation under a NiSource Retiree Welfare Plan with respect to a Business
Employee (and, if applicable, such Business Employee’s participating spouse and/or dependents) or Surviving Dependent shall be credited or applied to the annual or lifetime benefit limitation for such Business Employee (and, if applicable, such
Business Employee’s participating spouse and/or dependents) or Surviving Dependent under the corresponding Columbia Retiree Welfare Plan. 

(c) Retiree Welfare Plan Liabilities. 

(1) Columbia Liabilities. Except as provided in clause (2) of this Section 4.06(c), the Columbia Parties and
the Columbia Retiree Welfare Plans, as applicable, shall retain and be responsible for all claims for retiree welfare benefits (and for any Liabilities arising as a result of such claims) incurred with respect to any Business Employee (and, if
applicable, such Business Employee’s participating spouse and/or dependents) or Surviving Dependent on or after the Distribution Date under the Columbia Retiree Welfare Plans, and none of the NiSource Parties nor the NiSource Retiree Welfare
Plans shall assume or retain any such Liabilities. 
 (2) NiSource Liabilities. NiSource and the NiSource Retiree
Welfare Plans shall continue to be responsible for all claims for retiree welfare benefits (and for any Liabilities arising as a result of such claims) incurred with respect to any Business Employee (and, if applicable, such Business Employee’s
participating spouse and/or dependents) or Surviving Dependent prior to the Distribution Date, whether such claims have been paid or remain unpaid as of such date, and neither Columbia nor the Columbia Retiree Welfare Plans shall assume or retain
any such Liabilities. 
 (3) Claims Incurred. Claims for retiree health benefits shall be considered to be incurred
prior to the Distribution Date if the services related to such claims were provided prior to the Distribution Date. Claims for all other retiree welfare benefits shall be considered to be incurred prior to the Distribution Date if the date of loss
occurred prior to the Distribution Date. 

  
 14 

 (d) Retiree Welfare Plan VEBA Trusts. 

(1) Columbia Retiree VEBA Trusts. Effective on or before the Distribution Date, Columbia shall adopt, establish and
maintain Columbia Life and Medical VEBA Trusts and Columbia Post-65 Retiree Medical VEBA Trusts that in each case shall be substantially similar to the NiSource Life and Medical VEBA Trusts and NiSource Post-65 Retiree Medical VEBA Trusts, as
applicable, and are intended to be qualified under section 501(c)(9) of the Code. As soon as practicable after the adoption of the Columbia Life and Medical VEBA Trusts and the Columbia Post-65 Retiree Medical VEBA Trusts, Columbia shall submit
applications for determination to the IRS for a determination that each Columbia Life and Medical VEBA Trust and Columbia Post-65 Retiree Medical VEBA Trust is qualified under Section 501(c)(9) of the Code and is exempt from federal income tax
under Section 501(a) of the Code, and shall take any actions not inconsistent with Columbia’s other general commitments contained in this Agreement and make any amendments necessary to receive such determination. 

(2) Life and Medical VEBA Trusts. As soon as administratively practicable following the Distribution Date, the NiSource
Parties shall cause the trustees of the NiSource Life and Medical VEBA Trusts to transfer to the Columbia Life and Medical VEBA Trusts the assets that are credited to each of the subaccounts thereunder that relate to the Business Employees. 

(3) Post-65 Retiree Medical VEBA Trusts. As soon as administratively practicable following the Distribution Date, the
NiSource Parties shall cause the trustees of the NiSource Post-65 Retiree Medical VEBA Trusts to transfer to the Columbia Post-65 Retiree Medical VEBA Trusts the assets that are credited to each of the subaccounts thereunder that relate to the
Business Employees.
 ARTICLE V 

NON-ERISA BENEFIT ARRANGEMENTS 

5.01 Columbia Non-ERISA Benefit Arrangements. Effective on or before the Distribution Date, the Columbia Parties shall adopt, establish
and maintain Non-ERISA Benefit Arrangements for the benefit of the Business Employees that shall be substantially similar to the NiSource Non-ERISA Benefit Arrangements. 

5.02 Annual Bonuses. On or before March 15, 2016, the Columbia Parties shall pay to each Business Employee who is granted a
Corporate Incentive Plan award issued under the NiSource Inc. 2010 Omnibus Incentive Plan (a “CIP Award”), with respect to the 2015 performance period ending on the Distribution Date, a cash payment equal to the CIP Award
earned by such Business Employee for such period pursuant to the terms of the NiSource Inc. Corporate Incentive Plan. Prior to the date of such payment, the NiSource Parties shall provide to 

  
 15 

 
Columbia documentation detailing the amount of the CIP Award payable to each Business Employee and shall make a cash payment to Columbia in an amount equal to the aggregate amount of such CIP
Awards. Effective as of the Distribution Date, the Columbia Parties shall establish an annual bonus program for the benefit of the Business Employees that provides for the payment of annual bonuses for the 2015 performance period that begins on the
Distribution Date and for subsequent fiscal years that begin after the Distribution Date, and the Columbia Parties shall be solely responsible for the payment of all bonuses earned under such program. 

5.03 Severance. On or before the Distribution Date, the Columbia Parties shall assume, or enter into substantially similar change in
control severance agreements with respect to, each change in control severance agreement between a NiSource Party and a Business Employee, and shall be solely responsible for all obligations of the NiSource Parties under such agreements. Effective
on or before the Distribution Date, the Columbia Parties shall establish severance policies for the benefit of Business Employees that are substantially similar to the severance polices maintained by NiSource immediately prior to the Distribution
Date. Effective as of the Distribution Date, Columbia shall assume, and NiSource shall have no liability or obligation with respect to, the severance benefits provided to Business Employees. Following the Distribution Date, the Columbia Parties
shall be solely responsible for administering and paying all benefits under the applicable severance plans, policies or agreements with Business Employees, including Business Employees whose employment terminated prior to the Distribution Date for
an eligible reason under such policies or in accordance with such agreements. It is not intended that any Business Employee will be eligible for termination or severance payments or benefits from any NiSource Party as a result of the transfer or
change of employment from NiSource to any Columbia Party. Notwithstanding the preceding sentence, in the event that any such termination or severance payments or benefits become payable on account of such transfer, change or the refusal of a
Business Employee to accept employment with any Columbia Party, the Columbia Parties shall indemnify each of the NiSource Parties for the amount of such termination or severance payments or benefits. 

ARTICLE VI 
 STOCK PLANS

 6.01 Columbia Stock Plans. Effective on or before the Distribution Date, the Columbia Parties shall adopt, establish and
maintain Columbia Stock Plans that are substantially similar to the NiSource Stock Plans (the “Columbia Stock Plans”). 

6.02 Restricted Stock Units. 

(a) RSUs Held by Columbia Employees and Columbia Non-Employee Directors. NiSource and Columbia shall take any and
all action as shall be necessary or appropriate, including approval of the provisions of this Section 6.02(a) by the Columbia Board and the NiSource Compensation Committee pursuant to the terms of the applicable NiSource Stock Plan, the
applicable Columbia Stock Plan and this Agreement, so that each NiSource RSU Award held at the close of business on the Distribution Date by any Columbia Employee or non-employee director of Columbia shall be replaced with a substitute Columbia
restricted stock unit award granted under the applicable Columbia Stock Plan (a “Substitute Columbia RSU Award”). The number of Columbia 

  
 16 

 
restricted stock units subject to the Substitute Columbia RSU Award will be equal to the number of NiSource restricted stock units subject to the NiSource RSU Award held by the participant at the
close of business on the Distribution Date multiplied by a fraction, the numerator of which is the NiSource Pre-Distribution Stock Price, and the denominator of which is the Columbia Post-Distribution Stock Price. Each Substitute Columbia RSU Award
shall vest and be payable based on the holder’s employment or service with the Columbia Parties. Each Substitute Columbia RSU Award shall have substantially the same terms and conditions as the corresponding NiSource RSU Award, except as
provided herein. 
 (b) RSUs Held by Persons Other Than Columbia Employees and Columbia Non-Employee Directors.
NiSource shall take any and all action as shall be necessary or appropriate, including approval of the provisions of this Section 6.02(b) by the NiSource Compensation Committee pursuant to the terms of the applicable NiSource Stock Plan and
this Agreement, so that each NiSource RSU Award held at the close of business on the Distribution Date by any person who is not a Columbia Employee or non-employee director of Columbia shall be adjusted (an “Adjusted NiSource RSU
Award”). The number of NiSource restricted stock units subject to the Adjusted NiSource RSU Award will be equal to the number of NiSource restricted stock units subject to the NiSource RSU Award held by the holder at the close of
business on the Distribution Date multiplied by a fraction, the numerator of which is the NiSource Pre-Distribution Stock Price, and the denominator of which is the NiSource Post-Distribution Stock Price. Each Adjusted NiSource RSU Award shall have
substantially the same terms and conditions as the corresponding NiSource RSU Award, except as provided herein. 
 6.03 Performance Share
Awards. 
 (a) Performance Share Awards Held by Columbia Employees. 

(1) 2013 Performance Share Awards. NiSource and Columbia shall take any and all action as shall be necessary or
appropriate, including approval of the provisions of this Section 6.03(a)(1) by the Columbia Board and the NiSource Compensation Committee pursuant to the terms of the applicable NiSource Stock Plan, the applicable Columbia Stock Plan and this
Agreement, so that each NiSource Performance Share Award granted under a NiSource Stock Plan in 2013 and held at the close of business on the Distribution Date by any Columbia Employee will be replaced with a Substitute Columbia RSU Award granted
under the applicable Columbia Plan. The number of NiSource Shares earned pursuant to the NiSource Performance Share Award shall be determined by the NiSource Compensation Committee based on performance results through the Distribution Date. The
number of such NiSource Shares that are earned shall then be converted into a Substitute Columbia RSU Award by multiplying the number of such earned NiSource Shares by a fraction, the numerator of which is the NiSource Pre-Distribution Stock Price
and the denominator of which is the Columbia Post-Distribution Stock Price. Each Substitute Columbia RSU Award shall continue to vest based on holder’s service with the Columbia Parties, and shall have the same terms and conditions as the
corresponding NiSource Performance Share Award, except as provided herein. 

  
 17 

 (2) 2014 Performance Share Awards. NiSource and Columbia shall take any
and all action as shall be necessary or appropriate, including approval of the provisions of this Section 6.03(a)(2) by the Columbia Board and the NiSource Compensation Committee pursuant to the terms of the applicable NiSource Stock Plan, the
applicable Columbia Stock Plan and this Agreement, so that each NiSource Performance Share Award granted under a NiSource Stock Plan in 2014 and held at the close of business on the Distribution Date by any Columbia Employee will be replaced with a
Substitute Columbia RSU Award granted under the applicable Columbia Stock Plan. With respect to 50% of such NiSource Performance Share Award, the number of NiSource Shares that are deemed to have been earned as of the Distribution Date shall be
equal to 50% of the target number of NiSource Shares subject to such NiSource Performance Share Award. With respect to the remaining 50% of such NiSource Performance Share Award, the number of NiSource Shares earned shall be determined by the
NiSource Compensation Committee based on performance results through the Distribution Date. The number of such NiSource Shares that are earned or deemed to have been earned shall then be converted into a Substitute Columbia RSU Award by multiplying
the number of such earned NiSource Shares by a fraction, the numerator of which is the NiSource Pre-Distribution Stock Price and the denominator of which is the Columbia Post-Distribution Stock Price. Each Substitute Columbia RSU Award shall
continue to vest based on the holder’s service with the Columbia Parties, and shall have the same terms and conditions as the corresponding NiSource Performance Share Award, except as provided herein. 

(b) Performance Share Awards Held by Persons Other Than Columbia Employees. 

(1) 2013 Performance Share Awards. NiSource shall take any and all action as shall be necessary or appropriate,
including approval of the provisions of this Section 6.03(b)(1) by the NiSource Compensation Committee pursuant to the terms of the applicable NiSource Stock Plan and this Agreement, so that each NiSource Performance Share Award granted under a
NiSource Stock Plan in 2013 and held at the close of business on the Distribution Date by any person who is not a Columbia Employee will be adjusted and paid under the terms of the NiSource Stock Plan and applicable award agreement. The number of
NiSource Shares earned pursuant to the NiSource Performance Share Award shall be determined by the NiSource Compensation Committee based on performance results through the Distribution Date. The number of such NiSource Shares that are earned shall
then be multiplied by a fraction, the numerator of which is the NiSource Pre-Distribution Stock Price, and the denominator of which is the NiSource Post-Distribution Stock Price. Awards shall continue to vest based on the holder’s continued
service with the NiSource Parties. 

  
 18 

 (2) 2014 Performance Share Awards. NiSource shall take any and all action
as shall be necessary or appropriate, including approval of the provisions of this Section 6.03(b)(2) by the NiSource Compensation Committee pursuant to the terms of the applicable NiSource Stock Plan and this Agreement, so that each NiSource
Performance Share Award granted under a NiSource Stock Plan in 2014 and held at the close of business on the Distribution Date by any person who is not a Columbia Employee will be adjusted and paid under the terms of the NiSource Stock Plan and
applicable award agreement. With respect to 50% of such NiSource Performance Share Award, the number of NiSource Shares that are deemed to have been earned as of the Distribution Date shall be equal to 50% of the target number of NiSource Shares
subject to such NiSource Performance Share Award. With respect to the remaining 50% of such NiSource Performance Share Award, the number of NiSource Shares earned shall be determined by the NiSource Compensation Committee based on performance
results through the Distribution Date. The number of such NiSource Shares that are earned or deemed to have been earned shall then be multiplied by a fraction, the numerator of which is the NiSource
Pre-Distribution Stock Price, and the denominator of which is the NiSource Post-Distribution Stock Price. Each Adjusted NiSource RSU Award shall continue to vest based on the holder’s continued service
with the NiSource Parties. 
 6.04 Phantom Shares. 

(a) Phantom Stock Units Held by Columbia Employees. NiSource and Columbia shall take any and all action as shall
be necessary or appropriate, so that each NiSource Phantom Stock Unit Award held at the close of business on the Distribution Date by any Columbia Employee shall be replaced with a substitute Columbia phantom stock unit award granted under the
applicable Columbia Stock Plan (a “Substitute Columbia Phantom Stock Unit Award”). The number of Columbia phantom stock units subject to the Substitute Columbia Phantom Stock Unit Award will be equal to the number of NiSource
phantom stock units subject to the NiSource Phantom Stock Unit Award held by the participant at the close of business on the Distribution Date multiplied by a fraction, the numerator of which is the NiSource Pre-Distribution Stock Price, and the
denominator of which is the Columbia Post-Distribution Stock Price. Each Substitute Columbia Phantom Stock Unit Award shall vest and be payable based on the holder’s employment with the Columbia Parties.
Each Substitute Columbia Phantom Stock Unit Award shall have the same terms and conditions as the corresponding NiSource Phantom Stock Unit Award, except as provided herein. 

(b) Phantom Stock Units Held by Persons Other Than Columbia Employees. NiSource shall take any and all action as
shall be necessary or appropriate, so that each NiSource Phantom Stock Unit Award held at the close of business on the Distribution Date by any person who is not a Columbia Employee shall be adjusted (an “Adjusted NiSource Phantom Stock
Unit Award”). The number of NiSource phantom stock units subject to the Adjusted NiSource Phantom Stock Unit Award will be equal to the number of NiSource phantom stock units subject to the NiSource Phantom Stock Unit Award held by the
holder at the close of business on the Distribution Date multiplied by a 

  
 19 

 
fraction, the numerator of which is the NiSource Pre-Distribution Stock Price, and the denominator of which is the NiSource Post-Distribution Stock Price. Each Adjusted NiSource Phantom Stock
Unit Award shall have the same terms and conditions as the corresponding NiSource Phantom Stock Unit Award, except as provided herein. 

6.05 Employee Stock Purchase Plans.  

(a) Establishment of the Columbia Employee Stock Purchase Plan. On or before, but effective as of the close of
business on, the Distribution Date, Columbia shall adopt, establish and maintain an employee stock purchase plan (the “Columbia ESPP”) for the benefit of employees of the Columbia Parties that is substantially similar to the
NiSource Inc. Employee Stock Purchase Plan (the “NiSource ESPP”). 
 (b) Business
Employees’ NiSource ESPP Elections. Columbia shall cause the Columbia ESPP to recognize all elections made by the Business Employees under the NiSource ESPP in effect for the offering period beginning immediately prior to the
Distribution Date and shall apply such elections under the Columbia ESPP for the remainder of the period or periods for which such elections are by their terms applicable. Columbia shall also take any and all action as shall be necessary or
appropriate, so that each Business Employee’s election under the NiSource ESPP will be adjusted to permit Business Employees to purchase only Columbia Shares in lieu of purchasing NiSource Shares. 

6.06 Approval and Terms of Equity Awards. By approval of the Columbia Board and the NiSource Compensation Committee pursuant to
Sections 6.01, 6.02, 6.03, 6.04 and 6.05, Columbia, as issuer of substitute and replacement awards provided hereunder, and NiSource, as sole shareholder of Columbia, shall adopt and approve, respectively, the issuance of the substitute and
replacement awards provided for herein. Except as set forth above, the substitute Columbia equity awards shall be subject to the terms of the NiSource Stock Plan and applicable award agreements, except that references in such outstanding substitute
and replacement Columbia awards to “Board” and “Committee” shall mean the Board, Compensation Committee or any other designated committee of Columbia (as applicable) and references to the “Company” shall mean Columbia.
Notwithstanding the foregoing, substitute awards made under Columbia Stock Plans pursuant to Columbia’s obligations under this Agreement shall take into account all employment and service with both NiSource and Columbia, and their respective
Subsidiaries and Affiliates, for purposes of determining when such awards vest and terminate. 
 6.07 No Change in Control. The
Distribution will not constitute a “change in control” for purposes of NiSource equity awards that are outstanding as of the Distribution Date. 

ARTICLE VII 

COMPENSATION MATTERS 

AND GENERAL BENEFIT MATTERS 

7.01 Cessation of Participation in NiSource Plans and NiSource Non-ERISA Benefit Arrangements. Except as otherwise provided in this
Agreement or as required by the terms of any NiSource Plan or NiSource Non-ERISA Benefit Arrangement, or by applicable law, 

  
 20 

 
NiSource and Columbia shall take any and all action as shall be necessary or appropriate so that participation in NiSource Plans and NiSource Non-ERISA Benefit Arrangements by all Business
Employees shall terminate as of the close of business on the Distribution Date and the Columbia Parties shall cease to be participating employers under the terms of such NiSource Plans and NiSource Non-ERISA
Benefit Arrangements as of such time. 
 7.02 Assumption of Certain Employee Related Obligations. Except as otherwise provided in
this Agreement, effective as of the close of business on the Distribution Date, Columbia shall assume, and no NiSource Party shall have any further liability for, the following agreements, obligations and liabilities, and Columbia shall indemnify,
defend and hold harmless each of the NiSource Indemnified Parties from and against any and all Expenses or Losses incurred or suffered by one or more of the NiSource Indemnified Parties in connection with, relating to, arising out of or due to,
directly or indirectly, any of the following: 
 (a) all agreements entered into between any NiSource Party and any Business
Employee, independent contractor or other service provider providing services related to the Transferred Business; provided that if any such agreement constitutes a Shared Contract, the benefits, obligations and liabilities under such agreement
shall be allocated between NiSource and Columbia in accordance with Section 5.2 of the Distribution Agreement; 
 (b)
all collective bargaining agreements, collective agreements, trade union agreements or works council agreements entered into between any NiSource Party and any union, works council or other body to the extent they are related to the Business
Employees; 
 (c) all wages, salary, incentive compensation, commissions and bonuses payable to Business Employees on or
after the Distribution Date, without regard to when such wages, salary, incentive compensation, commissions or bonuses are or may have been earned; 

(d) all moving expenses and obligations related to relocation, repatriation, transfers or similar items incurred by or owed to
any Business Employee; 
 (e) all immigration-related, visa, work application or similar rights, obligations and liabilities
to the extent they are related to any Business Employees; 
 (f) all agreements entered into between (i) any NiSource
Party, Columbia Party or a Former Business owned, in whole or in part, by any of the Columbia Parties and (ii) any former director of a Columbia Party or a Former Business owned, in whole or in part, by any of the Columbia Parties (“Former
Columbia Directors”) providing for ongoing benefits and/or compensation for such Former Columbia Directors or such Former Columbia Directors’ spouses (e.g., ongoing payments of any director fees or ongoing payments related to Medicare
Supplement Insurance coverage); 
 (g) all offer letters and letter agreements entered into between (i) any NiSource
Party, Columbia Party or a Former Business owned, in whole or in part, by any of the Columbia Parties and (ii) any Business Employee providing for ongoing benefits and/or compensation for such Business Employee (e.g., enhanced severance
benefits or ongoing financial and tax planning assistance); and 
 (h) all liabilities and obligations whatsoever of the
Transferred Business with respect to claims made by or with respect to Business Employees, or any other to the extent their employment duties related to the Transferred Business, relating to any employee benefit plan, program or policy not otherwise
retained or assumed by NiSource pursuant to this Agreement, including such liabilities relating to actions or omissions of or by the Columbia Parties or any officer, director, employee or agent thereof prior to the Distribution Date. 

  
 21 

 7.03 Restrictive Covenants in Employment and Other Agreements. To the extent permitted
under applicable law, following the Distribution, the Columbia Parties shall be considered to be successors to the NiSource Parties for purposes of all agreements containing restrictive covenants (including confidentiality and non-competition provisions) between any NiSource Party and any Business Employee executed prior to the Distribution Date such that each NiSource Party and each Columbia Party shall all enjoy the rights and benefits
under such agreements, with respect to their respective business operations; provided, however, that (a) in no event shall any NiSource Party be permitted to enforce any restrictive covenants against any Business Employees in
their capacity as employees of any Columbia Party and (b) in no event shall any Columbia Party be permitted to enforce the restrictive covenant agreements against any NiSource employees in their capacity as employees of any NiSource Party. 

7.04 Past Service Credit. With respect to all Business Employees, as of the Distribution Date, the Columbia Parties shall recognize all
service recognized under the comparable NiSource Plans and NiSource Non-ERISA Benefit Arrangements for purposes of determining eligibility, participation, vesting and calculation of benefits under comparable
plans and programs maintained by the Columbia Parties, provided that there shall be no duplication of benefits for Business Employees under such Columbia Party plans and programs. NiSource will provide to Columbia copies of any records available to
NiSource to document such service, plan participation and membership and cooperate with Columbia to resolve any discrepancies or obtain any missing data for purposes of determining benefit eligibility, participation, vesting and calculation of
benefits with respect to the Business Employees. With respect to retaining, destroying, transferring, sharing, copying and permitting access to all such information, NiSource and Columbia shall each comply with all applicable Laws, regulations and
internal policies and each party shall indemnify and hold harmless the other party from and against any and all Liability, claims, actions and damages that arise from a failure (by the indemnifying party) to so comply with all applicable Laws,
regulations and internal policies applicable to such information. 
 7.05 Accrued Vacation Days Off. Effective as of the Distribution
Date, the Columbia Parties shall recognize and assume all liability for all vacation, holiday, sick leave and personal days off, including banked vacation, accrued by Business Employees as of the Distribution Date, and the Columbia Parties shall
credit each Business Employee with such days off accrual. 
 7.06 Leaves of Absence. The Columbia Parties shall continue to apply all
leave of absence policies as in effect immediately prior to the Distribution to inactive Business Employees who are on an approved leave of absence as of the Distribution Date. Leaves of absence taken by Business Employees prior to the Distribution
Date shall be deemed to have been taken as employees of Columbia. 

  
 22 

 7.07 NiSource Assets. Except as otherwise set forth herein, NiSource shall retain all
reserves, bank accounts, trust funds or other balances maintained with respect to NiSource Non-ERISA Benefit Arrangements. 

7.08 Further Cooperation; Personnel Records; Data Sharing. The parties shall provide each other such records and information as
reasonably necessary or appropriate to carry out their obligations under law, under this Agreement or for the purposes of administering their respective plans and policies, including information relating to the vesting, exercise and employment
status of persons holding equity compensation awards in the common stock of the other party. Each party shall be responsible for the accuracy of records and information provided to the other party pursuant to this Section 7.08 and shall
indemnify such other party for any losses caused by inaccurate information that it has provided. Subject to applicable law, all information and records regarding employment and personnel matters of Business Employees shall be accessed, retained,
held, used, copied and transmitted after the Distribution Date by Columbia in accordance with all Laws and policies relating to the collection, storage, retention, use, transmittal, disclosure and destruction of such records. Access to such records
after the Distribution Date will be provided to NiSource in accordance with Article IX of the Distribution Agreement. Notwithstanding the foregoing, NiSource shall retain reasonable access to those records necessary for NiSource’s
continued administration of any plans or programs on behalf of Business Employees after the Distribution Date, and Columbia shall retain reasonable access to those records necessary for Columbia’s administration of any equity award or other
compensation or benefit payable or administered by the Columbia Parties after the Distribution Date, provided that such access shall be limited to individuals who have a job-related need to access such records. NiSource shall also retain copies of
all confidentiality and non-compete agreements with any Business Employee in which NiSource has a valid business interest. With respect to retaining, destroying, transferring, sharing, copying and permitting
access to all such information, NiSource and Columbia shall each comply with all applicable Laws, regulations and internal policies, and each party shall indemnify and hold harmless the other party from and against any and all liability, claims,
actions and damages that arise from a failure (by the indemnifying party) to so comply with all applicable Laws, regulations and internal policies applicable to such information. 

ARTICLE VIII 
 GENERAL
PROVISIONS 
 8.01 Employment and Plan Rights. Notwithstanding anything to the contrary in this Agreement, the Parties expressly
acknowledge and agree that (a) this Agreement is not intended to create an employment-related contract between any of the NiSource Parties or the Columbia Parties, on the one hand, and any employee or
service provider, on the other, nor may any current or former employee or service provider rely on this Agreement as the basis for any breach of any employment-related contract claim against any of the
NiSource Parties or Columbia Parties, (b) nothing in this Agreement shall be deemed or construed to require any of the NiSource Parties or Columbia Parties to continue to employ any particular employee or service provider for any period before
or after the Distribution Date, (c) nothing in this Agreement shall be deemed or 

  
 23 

 
construed to limit the right of the NiSource Parties or Columbia Parties to terminate the employment of any employee or service provider at any time before or after the Distribution Date and
(d) nothing in this Agreement shall be construed as establishing or amending any Pension Plan, Welfare Plan or Non-ERISA Benefit Arrangement, or any other plan, policy, agreement or arrangement for the benefit of any employee or any other
person. 
 8.02 Labor Relations. To the extent required by applicable law or any Contract or arrangement with a labor union, works
council or similar employee organization, Columbia shall provide notice, engage in consultation and take any similar action which may be required on its part in connection with the Distribution and shall fully indemnify each NiSource Party against
any Liabilities arising from its failure to comply with such requirements. 
 8.03 Confidentiality. Each Party agrees that any
information conveyed or otherwise received by or on behalf of a Party in conjunction herewith is confidential and is subject to the terms of the confidentiality provisions set forth in Section 9.8 of the Distribution Agreement. 

8.04 Administrative Complaints/Litigation. Except as otherwise provided in this Agreement, following the Distribution Date, Columbia
shall assume, and be solely liable for, the handling, administration, investigation and defense of actions, including ERISA, occupational safety and health, employment standards, union grievances, wrongful dismissal, discrimination or human rights
and unemployment compensation claims, asserted at any time against NiSource or Columbia by any Business Employee (including any dependent or beneficiary of any Business Employee), or any other person to the extent such actions or claims arise out of
or relate to employment or the provision of services (whether as an employee, contractor, consultant or otherwise) to or with the Transferred Business. Any Losses arising from such actions shall be deemed Assumed Actions under the Distribution
Agreement. 
 8.05 Reimbursement and Indemnification. The parties hereto agree to reimburse each other, within 30 days of
receipt from the other party of appropriate verification, for all costs and expenses which each may incur on behalf of the other as a result of any of the Welfare Plans, Pension Plans and Non-ERISA Benefit
Arrangements and, as contemplated by Section 5.03, any termination or severance payments or benefits. All liabilities retained, assumed or indemnified against by Columbia pursuant to this Agreement shall be subject to indemnification under
Section 8.2 of the Distribution Agreement and all liabilities retained, assumed or indemnified against by NiSource pursuant to this Agreement shall be subject to indemnification under Section 8.3 of the Distribution Agreement, and all such
liabilities shall be subject to the indemnification procedures set forth in Article VIII of the Distribution Agreement. 
 8.06
Entire Agreement. This Agreement, including any schedules hereto and the sections of the Distribution Agreement referenced herein, constitutes the entire agreement between the parties with respect to the subject matter contained herein, and
supersedes all prior agreements, negotiations, discussions, understandings, writings and commitments between any of the NiSource Parties, on the one hand, and any of the Columbia Parties, on the other hand, with respect to such subject matter
contained herein. 
 8.07 Dispute Resolution. The parties agree that any dispute, controversy or claim between them with respect to
the matters covered hereby shall be governed by and resolved in accordance with Section 10.2 of the Distribution Agreement. 

  
 24 

 8.08 Governing Law. This Agreement shall be governed by and construed in accordance with
the internal Laws (as opposed to the conflicts of Law provisions) of the State of Delaware. 
 8.09 Submission to Jurisdiction; Waiver of
Jury Trial. Each of NiSource, on behalf of itself and each of the NiSource Parties, and Columbia, on behalf of itself and each of the Columbia Parties, hereby irrevocably (a) submits in any Dispute to the exclusive jurisdiction of the
United States District Court for the Northern District of Illinois and the jurisdiction of any court of the State of Illinois located in Chicago, Illinois, (b) waives any and all objections to jurisdiction that it may have under the Laws of the
State of Illinois or the United States, (c) agrees that service of any process, summons, notice or document by U.S. registered mail to its respective address set forth in Section 10.11 of the Distribution Agreement shall be effective
service of process for any litigation brought against it in any such court and (d) UNCONDITIONALLY WAIVES ANY RIGHT IT MAY HAVE TO TRIAL BY JURY IN CONNECTION WITH ANY DISPUTE (AS DEFINED IN THE DISTRIBUTION AGREEMENT). 

8.10 Amendment. This Agreement shall not be amended, modified or supplemented except by a written instrument signed by an authorized
representative of each of NiSource and Columbia. 
 8.11 Waiver. Any term or provision of this Agreement may be waived, or the time
for its performance may be extended, by the party or parties entitled to the benefit thereof. Any such waiver shall be validly and sufficiently given for the purposes of this Agreement if, as to any party, it is in writing signed by an authorized
representative of such party. The failure of either party to enforce at any time any provision of this Agreement shall not be construed to be a waiver of such provision, or in any way to affect the validity of this Agreement or any part hereof or
the right of any party thereafter to enforce each and every such provision. No waiver of any breach of this Agreement shall be held to constitute a waiver of any other or subsequent breach. 

8.12 Partial Invalidity. Wherever possible, each provision hereof shall be construed in a manner as to be effective and valid under
applicable Law, but in case any one or more of the provisions contained herein shall, for any reason, be held to be invalid, illegal or unenforceable in any respect, such provision shall be ineffective to the extent, but only to the extent of such
invalidity, illegality or unenforceability without invalidating the remainder of such invalid, illegal or unenforceable provision or provisions or any other provision hereof, unless such a construction would be unreasonable. 

8.13 Execution in Counterparts. This Agreement may be executed in counterparts, each of which shall be deemed an original instrument,
but both of which shall be considered one and the same agreement, and shall become binding when the counterparts have been signed by and delivered to each of the parties hereto. Delivery of an executed counterpart of a signature page to this
Agreement by facsimile or.pdf shall be as effective as delivery of a manually executed counterpart to this Agreement. 
 8.14 Successors
and Assigns. This Agreement shall be binding upon and inure to the benefit of the parties and their successors and permitted assigns; provided, however, that the rights and obligations of either party under this Agreement shall not
be assignable by such party without the prior written consent of the other party. The successors and permitted assigns hereunder shall include any permitted assignee as well as the successors in interest to such permitted assignee (whether by
merger, liquidation (including successive mergers or liquidations) or otherwise). 

  
 25 

 8.15 No Third-Party Beneficiaries. No Business Employee or other current or former
employee of the NiSource Parties or Columbia Parties (or his/her spouse, dependent or beneficiary), or any other person not a party to this Agreement, shall be entitled to assert any claim hereunder. The provisions of this Agreement are solely for
the benefit of the parties hereto and their respective successors and permitted assigns, and nothing herein express or implied shall give or be construed to give to any other Person any legal or equitable rights hereunder. 

8.16 Notices. All notices or other communications under this Agreement shall be in writing and shall be deemed to be duly given when
delivered or mailed in accordance with the terms of Section 10.11 of the Distribution Agreement. 
 8.17 Performance. NiSource
will cause to be performed and hereby guarantees the performance of all actions, agreements and obligations set forth herein to be performed by any NiSource Party. Columbia will cause to be performed and hereby guarantees the performance of all
actions, agreements and obligations set forth herein to be performed by any Columbia Party. This Agreement is being entered into by NiSource and Columbia on behalf of themselves and the members of their respective groups (the NiSource Parties and
the Columbia Parties). This Agreement shall constitute a direct obligation of each such entity and shall be deemed to have been readopted and affirmed on behalf of any Person that becomes a Subsidiary of NiSource or Columbia on and after the
Effective Time. 
 8.18 Force Majeure. No party shall be deemed in default of this Agreement to the extent that any delay or failure
in the performance of its obligations under this Agreement results from any cause beyond its reasonable control and without its fault or negligence, including acts of God, acts of civil or military authority, embargoes, acts of terrorism, epidemics,
war, riots, insurrections, fires, explosions, earthquakes, floods, unusually severe weather conditions, labor problems or unavailability of parts, or, in the case of computer systems, any failure in electrical or air conditioning equipment. In the
event of any such excused delay, the time for performance shall be extended for a period equal to the time lost by reason of the delay. A party claiming the benefit of this provision shall, as soon as reasonably practicable after the occurrence of
any such event, (a) notify the other party of the nature and extent of any such force majeure condition and (b) use due diligence to remove any such causes and resume performance under this Agreement as soon as reasonably feasible. 

8.19 No Public Announcement. Neither party hereto shall, without the prior written approval of the other party, make any press release
or other public announcement concerning the transactions contemplated by this Agreement, except as and to the extent that any such party shall be so obligated by Law or the rules of any regulatory body or stock exchange, in which case the other
party shall be advised and the parties shall use their respective commercially reasonable efforts to cause a mutually agreeable release or announcement to be issued; provided, however, that the foregoing shall not preclude
communications or disclosures necessary to implement the provisions of this Agreement or to comply with the accounting and SEC disclosure obligations or the rules of any stock exchange. 

  
 26 

 8.20 Limited Liability. Notwithstanding any other provision of this Agreement, no Person
who is a stockholder, director, employee, officer, agent or Representative of Columbia or NiSource, in such individual’s capacity as such, shall have any liability in respect of or relating to the covenants or obligations of Columbia or
NiSource, as applicable, under this Agreement or any Transaction Agreement or in respect of any certificate delivered with respect hereto or thereto, and, to the fullest extent legally permissible, each of Columbia and NiSource, for itself and its
stockholders, directors, employees, officers and Affiliates, waives and agrees not to seek to assert or enforce any such liability that any such individual otherwise might have pursuant to applicable Law. 

8.21 Effect if Distribution Does Not Occur. Notwithstanding anything in this Agreement to the contrary, if the Distribution Agreement
is terminated prior to the Distribution, this Agreement shall be of no further force and effect. 
 8.22 Miscellaneous. Except as
otherwise expressly set forth in this Agreement, the provisions of Article X of the Separation and Distribution Agreement shall apply mutatis mutandis to this Agreement. 

  
 27 

 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be executed by their
authorized representatives as of the date first above written. 
  

			
	NISOURCE INC.
		
	By:		  

	Name:		
	Title:		
	
	COLUMBIA PIPELINE GROUP, INC.
		
	By:		  

	Name:		
	Title:

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00244-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00244-of-00352.parquet"}]]