Document:

Executive Chairman Agreement

 Exhibit 10.1 
 Renovis, Inc. 
 October 1, 2007 
 Mr. John Walker 
 [Address] 
  

	 	Re:	Executive Chairman Agreement 

 Dear John: 
 On behalf of Renovis, Inc. (the “Company”), I am pleased to offer you the position of Executive Chairman and Principal Executive Officer
of the Company on the terms and conditions set forth in this letter agreement (this “Agreement”). You have agreed to accept this role, which is in addition to your current role as Chairman of the Board of Directors of the Company
(the “Board”), while we work towards consummating our merger with Evotec AG. You may accept this Agreement by signing and returning a copy of this Agreement to the Company as provided below. 
 1. Term of Agreement. Your services under this Agreement shall commence on October 2, 2007 (the “Effective Date”), and
continue until the earliest to occur of: (i) the consummation of our merger with Evotec AG, or (ii) your resignation from this position or the termination of your service by us (each of the foregoing, the “Separation
Date”). Following the Separation Date, to the extent you are then Chairman of the Board, or a member of the Board (if not Chairman of the Board), your duties will revert to solely those of Chairman of the Board or a member of the Board, as
applicable. This Agreement is terminable at will by you or the Company at any time (for any reason or for no reason) in accordance with Section 7 of this Agreement. If this Agreement terminates for any reason, you shall not be entitled to any
payments, benefits, damages, awards or other compensation other than as provided in this Agreement. 
 2. Position and Duties. During
the term of this Agreement, you shall serve as Executive Chairman and Principal Executive Officer of the Company. Your duties and authority as Executive Chairman and Principal Executive Officer shall be prescribed by the Board and provided by the
Company’s bylaws and shall be commensurate with those of an executive chairman of a company of comparable size and with a similar business as the Company. 
 3. Status. Your status with respect to your services to the Company hereunder shall be as an independent contractor and not an employee or agent of the Company for the purposes of any employee benefit program,
income tax withholding, FICA taxes, unemployment benefits or the like. 
 4. Chairman of the Board. You hereby acknowledge that the
responsibilities contemplated under this Agreement are in addition to your responsibilities and duties as Chairman of the Board. You hereby acknowledge that re-election to the Board as Chairman and as a member of the Board shall be governed by the
terms of the certificate of incorporation and bylaws of the Company. 

 October 1, 2007 
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 5. Compensation and Benefits. In consideration for your services to the Company, you shall
receive the following compensation and benefits from the Company. 
 (a) Deferred
Stock Units. As consideration for your services as Executive Chairman and Principal Executive Officer, the Company shall grant you pursuant to the Amended and Restated Renovis, Inc. 2003 Stock Plan, as may be amended from time to time (the
“Plan”), subject to approval of the Board, deferred stock units with respect to 100,000 shares of the Company’s common stock (the “DSU Grant”). The DSU Grant shall vest with respect to 1/36th of the total shares subject to the DSU Grant on each monthly anniversary of the Effective Date, subject to your continued service to the Company on each of
the vesting dates, including your service as a member of the Board. The vested shares of Company common stock subject to your DSU Grant shall be issued to you as soon as administratively practicable after the earliest to occur of (i) a date
specified by the Company that is between January 1 and March 15 of the calendar year following the calendar year of the vesting date, (ii) your separation from service with the Company, (iii) your death or disability or
(iv) a Change in Control (as defined in the Plan), including the consummation of our merger with Evotech AG. Immediately prior to the consummation of a Change in Control, twenty-five percent (25%) of the total shares subject to the DSU
Grant shall vest, such that the total shares vested as of the consummation of a Change in Control would equal the sum of (i) 25,000 and (ii) (a) 1/36th of the total shares subject to the DSU Grant multiplied by (b) the number of full months of continued service provided by you as of the date of consummation of a Change in Control. Following any such Change in
Control, the shares subject to the DSU Grant shall continue to vest at a rate of 1/36th of the total shares originally subject to the DSU Grant on each
monthly anniversary of the Effective Date thereafter, subject to your continued service to the Company. The DSU Grant shall otherwise be subject to the terms and conditions set forth in the Plan and the agreement to be entered into evidencing the
DSU Grant. 
 (b) Expenses. The Company shall reimburse you for business expenses that are reasonable and
necessary for you to perform, and were incurred by you in the course of the performance of, your duties pursuant to this Agreement and in accordance with the Company’s general policies upon your submission of vouchers and an expense report in
such form as may be required by the Company consistent with the Company’s policies in place from time-to-time. 
 (c) Chairman
Compensation. During the term of your service as Chairman of the Board, you shall continue to receive the compensation to which you are entitled to as Chairman of the Board (currently consisting of quarterly cash retainers of $12,500 and an
annual stock option grant to purchase 22,000 shares of Company common stock). 
 6. Covenants. By accepting the terms of this
Agreement, you hereby agree to the following covenants in addition to any obligations you may have by law and make the following representations. 

 October 1, 2007 
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 (a) Confidentiality. You acknowledge that, in connection with your services to the Company,
you will have access to trade secrets of the Company and other information and materials which the Company desires to keep confidential, including customer lists, supplier lists, financial statements, business records and data, marketing and
business plans, and information and materials relating to the Company’s services, products, methods of operation, key personnel, proprietary software and other proprietary intellectual property and information disclosed to the Company of third
parties to which the Company owes a duty of nondisclosure (collectively, the “Confidential Information”); provided, however, that Confidential Information does not include information which (i) is or becomes
publicly known other than as a result of your actions in violation of this Agreement; (ii) is or becomes available to you from a source (other than the Company) that you reasonably believe is not prohibited from disclosing such information to
you by a contractual or fiduciary obligation to the Company, (iii) has been made available by the Company, directly or indirectly, to a non-affiliated third party without obligation of confidentiality; or (iv) you are obligated to produce
as a result of a court order or pursuant to governmental action or proceeding, provided that you give the Company prompt written notice of such requirement prior to such disclosure and assistance in obtaining an order protecting such Confidential
Information from public disclosure. You covenant and agree that, both during and after the term of your services to the Company, you will keep secret all Confidential Information and will not disclose, reveal, divulge or otherwise make known any
Confidential Information to any person (other than the Company or its employees or agents in the course of performing you duties hereunder) or use any Confidential Information for your own account or for the benefit of any other individual or
entity, except with the prior written consent of the Company. 
 (b) Ownership of Intellectual Property. You agree that all
inventions, copyrightable material, software, formulas, trademarks, trade secrets and the like which are developed or conceived by you in the course of your services to the Company or on the Company’s time or property (collectively, the
“Intellectual Property”) shall be disclosed promptly to the Company and the Company shall own all right, title and interest in and to the Intellectual Property. The parties expressly agree that any and all of the Intellectual
Property developed by you shall be considered works made-for-hire for the Company pursuant to the United States Copyright Act of 1976, as amended from time to time. In order to ensure that the Company shall own all right, title and interest in and
to the Intellectual Property in the event that any of the Intellectual Property is not deemed a work made-for-hire (as defined in the Copyright Act of 1976) and in any other event, you hereby sell and assign all right, title and interest in and to
all such Intellectual Property to the Company, and you covenant and agree to affix to the Intellectual Property appropriate legends and copyright notices indicating the Company’s ownership of all Intellectual Property and all underlying
documentation to the extent reasonably appropriate, and shall execute such instruments of transfer, assignment, conveyance or confirmation as the Company reasonably considers necessary to transfer, confirm, vest, perfect, maintain or defend the
Company’s right, title and interest in and to the Intellectual Property throughout the world. Your obligation under this Section 6(b) to assign to the Company inventions created or conceived by you shall not apply to an invention that you
developed 

 October 1, 2007 
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entirely on your own time without using the Company’s equipment, supplies, facilities, or trade secret information, provided that those inventions
(i) do not or did not relate directly, at the time of conception or reduction to practice of the invention, to the Company’s business as conducted at such time or actual or demonstrably anticipated research or development of the Company;
and (ii) do not or did not result from any work performed by you for the Company. 
 7. Termination. This Agreement may be
terminated by you at any time for any or no reason upon no less than thirty days prior notice. This Agreement may be terminated by the Company at any time for any or no reason. Upon the Separation Date, any outstanding options, deferred stock units
or other equity awards you hold shall continue vesting to the extent you continue to perform services to the Company, including if you continue to perform services in your capacity as a member of the Board, and to the extent you do not continue
performing services to the Company, shall immediately terminate with regard to the then-unvested portion (after taking into account any accelerated vesting). 
 8. Miscellaneous. 
 (a) This letter constitutes the complete, final and exclusive embodiment of
the entire agreement between you and the Company with regard to the terms and conditions of your services as Executive Chairman of the Company. It is entered into without reliance on any promise or representation, written or oral, other than those
expressly contained herein, and it supersedes any other such promises, warranties or representations and any other written or oral statements concerning your rights to any compensation, equity or benefits from the Company, its predecessors or
successors in interest. 
 (b) This Agreement may not be modified or amended except in a writing signed by both you and a duly
authorized officer of the Company. 
 (c) This Agreement may be signed in counterparts and the counterparts taken together shall
constitute one agreement. 
 (d) This Agreement shall be deemed to have been entered into and shall be construed and enforced in
accordance with the laws of the State of California as applied to contracts made and to be performed entirely within California. 
 (e)
If either party hereto brings any action to enforce his or its rights hereunder, the prevailing party in such action shall be entitled to be paid by the other party such prevailing party’s reasonably attorneys’ fees and costs incurred
in such action. 

 October 1, 2007 
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 If this Agreement is acceptable to you, please sign below and return the original, fully executed Agreement to the
Company. 
  

			
	Sincerely,
	
	RENOVIS, INC.
		
	By:	 	 /s/ Anthony B. Evnin, Ph.D.

		 	Anthony B. Evnin, Ph.D.
	Title:	 	Director and Chairman of the Compensation Committee

  

					
	AGREED AND ACCEPTED:	 		 	
			
	 /s/ John P. Walker
	 		 	October 2, 2007
	John P. Walker	 		 	DateForm of Deferred Stock Unit Award Grant Notice

 Exhibit 10.2 
 RENOVIS, INC. 
 2003 STOCK PLAN, AS AMENDED 
 DEFERRED STOCK UNIT AWARD GRANT NOTICE AND 
 DEFERRED STOCK AWARD AGREEMENT 
 Renovis, Inc., a Delaware corporation, (the “Company”), pursuant to its 2003 Stock
Plan, as amended, (the “Plan”), hereby grants to the individual listed below (“Participant”), an award of units of Deferred Stock (“Deferred Stock Units” or
“DSUs”) with respect to the number of shares of Stock set forth below (the “Shares”). This Deferred Stock Unit Award is subject to all of the terms and conditions as set forth herein and in the
Deferred Stock Unit Award Agreement attached hereto as Exhibit A (the “Deferred Stock Unit Agreement”) and the Plan, each of which are incorporated herein by reference. Unless otherwise defined herein, the terms
defined in the Plan shall have the same defined meanings in this Grant Notice and the Deferred Stock Unit Agreement. 
  

			
	Participant:	  	John Walker
		
	Grant Date:	  	October 2, 2007
		
	Vesting Commencement Date:	  	October 2, 2007
		
	Total Number of DSUs:	  	100,000
		
	Vesting Schedule:	  	 1/36 of the Deferred Stock Units shall vest for each calendar month of service after the Vesting Commencement Date, such that all of the Deferred
Stock Units are vested on October 1, 2010, subject to Participant’s continued employment or service with the Company or it successor through the applicable vesting date. Pursuant to the terms of the Deferred Stock Unit Agreement, immediately
prior to the consummation of a Change in Control, twenty-five percent (25%) of the Deferred Stock Units shall vest, such that the total Deferred Stock Units vested as of the consummation of a Change in Control would equal the sum of (i) 25,000 and
(ii) (a) 1/36th of the total shares subject to the Deferred Stock Units multiplied by (b) the number of full months of continued service provided by
Participant from the Vesting Commencement Date through the consummation of a Change in Control. Following any such Change in Control, the Deferred Stock Units shall continue to vest at a rate of 1/36th of the total number of Deferred Stock Units initially granted hereunder on each monthly anniversary of the Vesting Commencement Date thereafter, subject to Participant’s
continued service to the Company.
  
 In no event shall any Deferred Stock
Units vest following Participant’s termination of service with the Company or its Subsidiaries (a “Separation from Service”).

 By Participant’s signature and the Company’s signature below, Participant agrees to be bound by the terms and
conditions of the Plan, the Deferred Stock Unit Agreement and this Grant Notice. Participant has reviewed the Deferred Stock Unit Agreement, the Plan and this Grant Notice in their entirety, has had an opportunity to obtain the advice of counsel
prior to executing this Grant Notice and fully understands all provisions of this Grant Notice, the Deferred Stock Unit Agreement and the Plan. Participant hereby agrees to accept as binding, conclusive and final all decisions or interpretations of
the Company upon any questions arising under the Plan, this Grant Notice or the Deferred Stock Unit Agreement. 
  

									
	RENOVIS, INC.:	 		 	PARTICIPANT:
					
	By:	 	  
	 		 	By:	 	  

	Print Name:	 	Marlene Perry	 		 	Print Name:	 	  

	Title:	 	 SVP Human Resources
 and Facilities
	 		 		 	
	Address:	 	Two Corporate Drive	 		 	Address:	 	  

		 	So. San Francisco, CA 94080	 		 		 	  

 EXHIBIT A 
 TO DEFERRED STOCK UNIT AWARD GRANT NOTICE 
 RENOVIS, INC. DEFERRED STOCK UNIT AWARD AGREEMENT 

 Pursuant to the Deferred Stock Unit Award Grant Notice (the “Grant Notice”) to which this Deferred Stock Unit Award Agreement (the
“Agreement”) is attached, Renovis, Inc., a Delaware corporation (the “Company”) has granted to Participant the right to receive the number of Deferred Stock Units under the 2003 Stock Plan, as amended
from time to time (the “Plan”), as set forth in the Grant Notice. The Award is subject to the terms and conditions of the Plan which are incorporated herein by reference. In the event of any inconsistency between the Plan and
this Agreement, the terms of the Plan shall control. 
 1. Grant of the DSUs. As set forth in the Grant Notice, the Company hereby
grants the Participant DSUs in exchange for past and future services to the Company subject to all the terms and conditions in this Agreement, the Grant Notice and the Plan. However, no Shares shall be issued to the Participant until the time set
forth in Section 4. Prior to actual payment of any Shares, such DSUs will represent an unsecured obligation of the Company, payable only from the general assets of the Company. 
 2. Definitions. All capitalized terms used in this Agreement without definition shall have the meanings ascribed to them in the Plan and the Grant
Notice. Whenever used herein, “Change in Control” shall mean the consummation of any of the following transactions: 
 (a) the closing of a business combination (such as a merger or consolidation) of the Company with any other corporation or other type of business entity (such as a limited liability company), other than a business combination which would
result in the voting securities of the Company outstanding immediately prior thereto continuing to represent (either by remaining outstanding or by being converted into voting securities of the surviving entity) more than fifty percent (50%) of
the total voting power represented by the voting securities of the Company or such controlling surviving entity outstanding immediately after such business combination; or 
 (b) the sale, lease, exchange or other transfer or disposition by the Company of all or substantially all (more than seventy percent (70%)) of the
Company’s assets by value; or 
 (c) an acquisition of any voting securities of the Company by any “person” (as the term
“person” is used for purposes of Section 13(d) or Section 14(d) of the Exchange Act) immediately after which such person has “beneficial ownership” (within the meaning of Rule 13d-3 promulgated under the Exchange Act)
of more than fifty percent (50%) of the combined voting power of the Company’s then outstanding voting securities. 
 Acceleration of Vesting. Immediately prior to the consummation of a Change in Control,
twenty-five percent (25%) of the Deferred Stock Units shall vest, such that the total Deferred Stock Units vested as of the consummation of a Change in Control would equal the sum of (i) 25,000 and (ii) (a) 1/36th of the total shares subject to the Deferred Stock Units multiplied by (b) the number of full months of continued service provided by Participant from the
Vesting Commencement Date through the consummation of such Change in Control. Following any such Change in Control, the Deferred Stock Units shall continue to vest at a rate of 1/36th of the total number of Deferred Stock Units initially subject to this Agreement on each monthly anniversary of the Vesting Commencement Date thereafter, subject to Participant’s continued service to the Company.

 3. Issuance of Stock. 

 (a) Timing of Distribution. Shares shall be issued to the Participant with respect to vested DSUs
as soon as administratively practicable after the earliest to occur of the following: (i) a date specified by the Company that is between January 1 and March 15 of the calendar year following the calendar year of the vesting date,
(ii) the Participant’s Separation from Service, (iii) the Participant’s Disability, (iv) the Participant’s death, or (v) a Change in Control. 
 (b) General. Shares issued pursuant to this Section 4 shall be issued (either in book-entry form or otherwise) to the Participant or the
Participant’s beneficiaries, as the case may be. No fractional Shares shall be issued under this Agreement. In the event Participant ceases to be an Employee, consultant to the Company or member of the Board the DSUs shall cease vesting
immediately upon such cessation of service and any unvested DSUs awarded by this Agreement shall be forfeited. 
 4. Taxes.
Notwithstanding anything to the contrary in this Agreement, the Company shall be entitled to require payment to the Company or any of its Subsidiaries any sums required by federal, state or local tax law to be withheld with respect to the issuance
of the Deferred Stock Units, the distribution of shares of Stock with respect thereto, or any other taxable event related to the Deferred Stock Units. The Company may permit the Participant to make such payment in one or more of the forms specified
below: 
 (a) by cash or check made payable to the Company; 
 (b) by the deduction of such amount from other compensation payable to Participant; 
 (c) in the sole
discretion of the Company, by requesting that the Company withhold a net number of vested Shares otherwise issuable having a then current Fair Market Value not exceeding the amount necessary to satisfy the withholding obligation of the Company and
its Subsidiaries based on the minimum applicable statutory withholding rates for federal, state, local and foreign income tax and payroll tax purposes; or 
 (d) in any combination of the foregoing. 
 In the event Participant fails to provide timely payment of all sums required by
the Company pursuant to this Section 5, the Company shall have the right and option, but not obligation, to treat such failure as an election by Participant to satisfy all or any portion of his or her required payment obligation by means of
requesting the Company to withhold vested Shares otherwise issuable in accordance with clause (c) above. The Company shall not be obligated to deliver any new certificate representing Shares issuable with respect to the Deferred Stock Units to
Participant or Participant’s legal representative unless and until Participant or Participant’s legal representative shall have paid or otherwise satisfied in full the amount of all federal, state, local and foreign taxes applicable to the
taxable income of Participant resulting from the grant of the Deferred Stock Units, the distribution of the Shares issuable with respect thereto, or any other taxable event related to the Deferred Stock Units. 
 5. Rights as Stockholder. Neither the Participant nor any person claiming under or through the Participant will have any of the rights or
privileges of a stockholder of the Company in respect of any Shares deliverable hereunder unless and until certificates representing such Shares (which may be in book entry form) will have been issued and recorded on the records of the Company or
its transfer agents or registrars, and delivered to the Participant (including through electronic delivery to a brokerage account). After such issuance, recordation and delivery, the Participant will have all the rights of a stockholder of the
Company with respect to voting such Shares and receipt of dividends and distributions on such Shares. 

 6. Conditions to Issuance of Certificates. Notwithstanding any other provision of this Agreement,
the Company shall not be required to issue or deliver any certificate or certificates for any Shares prior to the fulfillment of all of the following conditions: (A) the admission of the Shares to listing on all stock exchanges on which such
Shares are then listed, (B) the completion of any registration or other qualification of the Shares under any state or federal law or under rulings or regulations of the Securities and Exchange Commission or other governmental regulatory body,
which the Company shall, in its sole and absolute discretion, deem necessary and advisable, (C) the obtaining of any approval or other clearance from any state or federal governmental agency that the Company shall, in its absolute discretion,
determine to be necessary or advisable and (D) the lapse of any such reasonable period of time following the date the DSUs vest as the Company may from time to time establish for reasons of administrative convenience. 
 7. Award Not Transferable. This grant and the rights and privileges conferred hereby will not be transferred, assigned, pledged or hypothecated in
any way (whether by operation of law or otherwise) and will not be subject to sale under execution, attachment or similar process. Upon any attempt to transfer, assign, pledge, hypothecate or otherwise dispose of this grant, or any right or
privilege conferred hereby, or upon any attempted sale under any execution, attachment or similar process, this grant and the rights and privileges conferred hereby immediately will become null and void. 
 8. Not a Contract of Employment. Nothing in this Agreement or in the Plan shall confer upon the Participant any right to continue to serve as a
service provider of the Company or any of its subsidiaries. 
 9. Governing Law. The laws of the State of Delaware shall govern the
interpretation, validity, administration, enforcement and performance of the terms of this Agreement regardless of the law that might be applied under principles of conflicts of laws. 
 10. Conformity to Securities Laws. The Participant acknowledges that the Plan and this Agreement are intended to conform to the extent necessary
with all provisions of the Securities Act of 1933, as amended, and the Exchange Act, and any and all regulations and rules promulgated thereunder by the Securities and Exchange Commission, including without limitation Rule 16b-3 under the Exchange
Act. Notwithstanding anything herein to the contrary, the Plan shall be administered, and the Awards are granted, only in such a manner as to conform to such laws, rules and regulations. To the extent permitted by applicable law, the Plan and this
Agreement shall be deemed amended to the extent necessary to conform to such laws, rules and regulations. 
 11. Amendment, Suspension and
Termination. To the extent permitted by the Plan, this Agreement may be wholly or partially amended or otherwise modified, suspended or terminated at any time or from time to time by the Committee or the Board, provided, that, except as
may otherwise be provided by the Plan, no amendment, modification, suspension or termination of this Agreement shall adversely effect the Award in any material way without the prior written consent of the Participant. 
 12. Notices. Notices required or permitted hereunder shall be given in writing and shall be deemed effectively given upon personal delivery or
upon deposit in the United States mail by certified mail, with postage and fees prepaid, addressed to the Participant to his address shown in the Company records, and to the Company at its principal executive office. 
 13. Successors and Assigns. The Company may assign any of its rights under this Agreement to single or multiple assignees, and this Agreement
shall inure to the benefit of the successors and assigns of the Company. Subject to the restrictions on transfer herein set forth, this Agreement shall be binding upon Participant and his or her heirs, executors, administrators, successors and
assigns. 

 14. Compliance in Form and Operation. This Agreement and the Deferred Stock Units are intended to
comply with Section 409A of the Code and the Treasury Regulations thereunder and shall be interpreted in a manner consistent with that intention.

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