Document:

<PAGE>
                                                                     EXHIBIT 4.3

NEITHER THESE SECURITIES NOR THE SECURITIES INTO WHICH THESE SECURITIES ARE
CONVERTIBLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR
THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM
REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "SECURITIES
ACT"), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN
EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR PURSUANT TO AN
AVAILABLE EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION
REQUIREMENTS OF THE SECURITIES ACT AND IN ACCORDANCE WITH APPLICABLE STATE
SECURITIES LAWS AS EVIDENCED BY A LEGAL OPINION OF COUNSEL TO THE TRANSFEROR TO
SUCH EFFECT, THE SUBSTANCE OF WHICH SHALL BE REASONABLY ACCEPTABLE TO THE
COMPANY. THE SECURITIES ISSUABLE UPON CONVERSION OF THESE SECURITIES MAY BE
PLEDGED IN CONNECTION WITH A BONA FIDE MARGIN ACCOUNT OR OTHER LOAN SECURED BY
SUCH SECURITIES.

                                      Date of Issuance:___________ ___, 200__(1)

                                                                               $

                           7.5% CONVERTIBLE DEBENTURE
                         DUE _____________ __, 200__(2)

      THIS DEBENTURE is one of a series of duly authorized and issued Debentures
of Matritech, Inc., a Delaware corporation, having a principal place of business
at 330 Nevada Street, Newton, Massachusetts 02460 (the "Company"), designated as
its 7.5% Convertible Debentures and issued pursuant to the Purchase Agreement
(the "Debentures").

      FOR VALUE RECEIVED, the Company promises to pay to
________________________ or its registered assigns (the "Holder"), the principal
sum of $_______________ on ________________ __, 200__(3) or such earlier date as
the Debentures are required or permitted to be repaid as provided hereunder (the
"Maturity Date") and to pay interest to the Holder on the aggregate unconverted
and then outstanding principal amount of this Debenture at the rate of 7.5% per
annum, payable quarterly on March 1, June 1, September 1 and December 1,
beginning on __________ __, 200__(4) and on each Conversion Date (as to that
principal amount then being converted), on each

----------
(1)   The applicable Closing Date.

(2)   36 months from the applicable Closing Date.

(3)   36 months from the applicable Closing Date.

(4)   The first such date after the applicable Closing Date.

                                       1
<PAGE>

Monthly Redemption Date (as to that principal amount then being redeemed) and on
the Maturity Date (except that, if any such date is not a Business Day, then
such payment shall be due on the next succeeding Business Day) (each such date,
an "Interest Payment Date"), in cash or shares of Common Stock (or a combination
thereof) at the Interest Conversion Rate; provided, however, payment in shares
of Common Stock may only occur if: (i) there is an effective Underlying Shares
Registration Statement pursuant to which the Holder is permitted to utilize the
prospectus thereunder to resell all of the shares of Common Stock to be issued
in lieu of cash (and the Company has not been notified that such effectiveness
will be interrupted in the foreseeable future), (ii) the Common Stock is listed
for trading on a Principal Market (and the Company has not been notified that
trading of the Common Stock on a Principal Market will be interrupted in the
foreseeable future), (iii) there is a sufficient number of authorized but
unissued and otherwise unreserved shares of Common Stock for the issuance of all
of the shares then issuable pursuant to the Transaction Documents as of such
date, including the shares to be issued for interest in lieu of cash on such
Interest Payment Date, and (iv) such issuance would be permitted in full without
violating the limitations set forth in clauses (A) or (B) of Section 4(a)(ii).
Subject to the terms and conditions herein, the decision whether to pay interest
hereunder in shares of Common Stock or cash shall be at the discretion of the
Company. Not less than 20 Trading Days prior to each Interest Payment Date, the
Company shall provide the Holder with written notice of its election to pay
interest hereunder either in cash or shares of Common Stock (the Company may
indicate in such notice that the election contained in such notice shall
continue for later periods until revised). Within 20 Trading Days prior to an
Interest Payment Date, the Company's election (whether specific to an Interest
Payment Date or continuous notice) shall be irrevocable as to such Interest
Payment Date. Subject to the aforementioned conditions, failure to timely
provide such written notice shall be deemed an election by the Company to pay
the interest on such Interest Payment Date in cash. Interest shall be calculated
on the basis of a 360-day year and shall accrue daily commencing on the Issuance
Date until payment in full of the principal sum, together with all accrued and
unpaid interest and other amounts which may become due hereunder, has been made.
Payment of interest in shares of Common Stock shall otherwise occur pursuant to
Section 4(b) and for purposes of the payment of interest in shares only, the
Interest Payment Date shall be deemed the Conversion Date. Interest shall cease
to accrue with respect to any principal amount converted, provided that the
Company in fact delivers the Underlying Shares issuable upon such conversion.
Interest hereunder will be paid to the Person in whose name this Debenture is
registered on the records of the Company regarding registration and transfers of
Debentures (the "Debenture Register"). Except as otherwise provided herein, if
at anytime the Company pays interest partially in cash and partially in shares
of Common Stock, then such payment shall be distributed ratably among the
Holders based upon the principal amount of Debentures held by each Holder. All
overdue accrued and unpaid interest to be paid hereunder shall entail a late fee
at the rate of 12% per annum (or such lower maximum amount of interest permitted
to be charged under applicable law) ("Late Fee") which will accrue daily, from
the date such interest is due hereunder through and including the date of
payment. EXCEPT AS OTHERWISE PROVIDED HEREIN, THE COMPANY MAY NOT PREPAY ANY
PORTION OF THE PRINCIPAL AMOUNT ON THIS DEBENTURE WITHOUT THE PRIOR WRITTEN
CONSENT OF THE HOLDER.

                                       2
<PAGE>

      This Debenture is subject to the following additional provisions:

      Section 1. Subject to restrictions on transfer contained in the
Transaction Documents, this Debenture is exchangeable for an equal aggregate
principal amount of Debentures of different authorized denominations, as
requested by the Holder surrendering the same. No service charge will be made
for such registration of transfer or exchange.

      Section 2. This Debenture has been issued subject to certain investment
representations of the original Holder set forth in the Purchase Agreement and
may be transferred or exchanged only in compliance with the terms hereof, the
Purchase Agreement and applicable federal and state securities laws and
regulations. During any 12 month period and except for transfers to an Affiliate
of the Holder, the Holder, collectively with successor Holders, may not transfer
this Debenture in more than two transactions to more than four assignees per
transaction. Prior to due presentment to the Company for transfer of this
Debenture, the Company and any agent of the Company may treat the Person in
whose name this Debenture is duly registered on the Debenture Register as the
owner hereof for the purpose of receiving payment as herein provided and for all
other purposes, whether or not this Debenture is overdue, and neither the
Company nor any such agent shall be affected by notice to the contrary.

      Section 3. Events of Default.

            (a) "Event of Default", wherever used herein, means any one of the
      following events (whatever the reason and whether it shall be voluntary or
      involuntary or effected by operation of law or pursuant to any judgment,
      decree or order of any court, or any order, rule or regulation of any
      administrative or governmental body):

                  (i) any default in the payment of the principal of, interest
            on or liquidated damages in respect of, any Debentures, free of any
            claim of subordination, as and when the same shall become due and
            payable (whether on a Conversion Date or the Maturity Date or by
            acceleration or otherwise) which default is not cured, if possible
            to cure, within 10 days of receipt of written notice of such default
            sent by the Holder;

                  (ii) the Company shall materially fail to observe or perform
            any other covenant, agreement or warranty contained in, or otherwise
            commit any material breach of any of the Transaction Documents
            (other than any breach separately addressed in another clause
            contained herein) which is not cured, if possible to cure, within 30
            days of written notice of such default sent by the Holder (except
            with respect to breaches pursuant to Sections 4.8 and 4.9 of the
            Purchase Agreement);

                  (iii) the Company or any of its subsidiaries shall commence,
            or there shall be commenced against the Company or any such
            subsidiary a case under any applicable bankruptcy or insolvency laws
            as now or hereafter in effect or any

                                       3
<PAGE>

            successor thereto, or the Company commences any other proceeding
            under any reorganization, arrangement, adjustment of debt, relief of
            debtors, dissolution, insolvency or liquidation or similar law of
            any jurisdiction whether now or hereafter in effect relating to the
            Company or any subsidiary thereof or there is commenced against the
            Company or any subsidiary thereof any such bankruptcy, insolvency or
            other proceeding, in each case, which remains undismissed for a
            period of 60 days; or the Company or any subsidiary thereof is
            adjudicated insolvent or bankrupt; or any order of relief or other
            order approving any such case or proceeding is entered; or the
            Company or any subsidiary thereof suffers any appointment of any
            custodian or the like for it or any substantial part of its property
            which continues undischarged or unstayed for a period of 60 days; or
            the Company or any subsidiary thereof makes a general assignment for
            the benefit of creditors; or the Company shall state that it is
            unable to pay its debts generally as they become due; or the Company
            or any subsidiary thereof shall call a meeting of its creditors with
            a view to arranging a composition, adjustment or restructuring of
            its debts; or the Company or any subsidiary thereof shall by any act
            or failure to act expressly indicate its consent to, approval of or
            acquiescence in any of the foregoing; or any corporate or other
            action is taken by the Company or any subsidiary thereof for the
            purpose of effecting any of the foregoing;

                  (iv) the Company shall default in any of its obligations under
            any other Debenture or any mortgage, credit agreement or other
            facility, indenture agreement, factoring agreement or other
            instrument under which there may be issued, or by which there may be
            secured or evidenced any indebtedness for borrowed money or money
            due under any long term leasing or factoring arrangement of the
            Company in an amount exceeding $150,000, whether such indebtedness
            now exists or shall hereafter be created and such default shall
            result in such indebtedness becoming or being declared due and
            payable prior to the date on which it would otherwise become due and
            payable;

                  (v) the Common Stock shall not be listed for quotation on or
            quoted for trading on the Nasdaq SmallCap Market, New York Stock
            Exchange, American Stock Exchange or the Nasdaq National Market
            (each, a "Principal Market") and shall not again be eligible for and
            quoted or listed for trading thereon within 10 Trading Days;

                  (vi) the Company shall agree to sell or dispose of all or in
            excess of 33% of its assets in one or more transactions (whether or
            not such sale would constitute a Change of Control Transaction) or
            shall redeem or repurchase more than a de minimis number of its
            outstanding shares of Common Stock or other equity securities of the
            Company (other than redemptions of Underlying Shares);

                                       4
<PAGE>

                  (vii) an Underlying Shares Registration Statement relating to
            the Underlying Shares issuable hereunder shall not have been
            declared effective by the Commission on or prior to the 150th
            calendar day after the Issuance Date;

                  (viii) if, during the Effectiveness Period (as defined in the
            Registration Rights Agreement), the effectiveness of the Underlying
            Shares Registration Statement lapses for any reason or the Holder
            shall not be permitted to resell Registrable Securities (as defined
            in the Registration Rights Agreement) under the Underlying Shares
            Registration Statement, in either case, and except as provided for
            in Section 3(h) of the Registration Rights Agreement (subject to
            timely payment of liquidated damages), for more than 10 consecutive
            Trading Days or 20 non-consecutive Trading Days during any 12 month
            period;

                  (ix) an Event (as defined in the Registration Rights
            Agreement) shall not have been cured to the satisfaction of the
            Holder prior to the expiration of thirty days from the Event Date
            (as defined in the Registration Rights Agreement) relating thereto
            (other than an Event resulting from a failure of an Underlying
            Shares Registration Statement to be declared effective by the
            Commission on or prior to the Effectiveness Date (as defined in the
            Registration Rights Agreement), which shall be covered by Section
            3(a)(vii));

                  (x) the Company shall fail for any reason to deliver
            certificates to a Holder on or prior to the seventh Trading Day
            after a Conversion Date pursuant to and in accordance with Section 4
            or the Company shall provide notice to the Holder, including by way
            of public announcement, at any time, of its intention not to comply
            with requests for conversions of any Debentures being made in
            accordance with the terms hereof;

                  (xi) the Company shall fail for any reason to deliver the
            payment in cash pursuant to a Buy-In (as defined herein) within
            seven days after notice thereof is delivered hereunder; or

                  (xii) the Company shall fail for any reason to deliver
            certificates free of the restrictive legend to a Holder on or prior
            to the seventh Trading Day after such certificate is delivered to
            the Company for removal of restrictive legend pursuant to and in
            accordance with Section 4.1 of the Purchase Agreement.

            (b)  If any Event of Default occurs and is continuing, the full
      principal amount of this Debenture (and, at the Holder's option, all other
      Debentures then held by such Holder), together with interest and other
      amounts owing in respect thereof, to the date of acceleration shall become
      at and upon the Holder's written election made to the Company, immediately
      due and payable in cash (except with respect to the payment of interest,
      which may be paid in

                                       5
<PAGE>

shares of Common Stock subject to the satisfaction of the conditions to any
payment of interest in shares of Common Stock) ("Event of Default Notice"). The
aggregate amount payable upon an Event of Default shall be equal to the
Mandatory Prepayment Amount; provided, however, if the Company delivers in full
the payment required hereunder on or before the 5th day after the date of the
Event of Default Notice, then the Company shall not be required to pay any
accrued but unpaid liquidated damages as part of the Mandatory Prepayment Amount
and the Company's obligations with respect to such liquidated damages shall be
deemed satisfied. Interest shall accrue on the Mandatory Prepayment Amount
hereunder from the 5th day after the date of the Event of Default Notice through
the date of prepayment in full thereof in an amount equal to the Late Fee, to
accrue daily from the date such payment is due hereunder through and including
the date of payment. All Debentures for which the full prepayment price
hereunder shall have been paid in accordance herewith shall promptly be
surrendered to or as directed by the Company. Except as otherwise expressly set
forth herein, the Holder need not provide and the Company hereby waives any
presentment, demand, protest or other notice of any kind, and the Holder may
immediately and without expiration of any grace period enforce any and all of
its rights and remedies hereunder and all other remedies available to it under
applicable law. Such election may be rescinded and annulled by Holder at any
time prior to payment hereunder and the Holder shall have all rights as a
Debenture holder until such time, if any, as the full payment under this Section
shall have been received by it. No such rescission or annulment shall affect any
subsequent Event of Default or impair any right consequent thereon.

      Section 4. Conversion.

      (a) (i) At any time  after  the  Closing  Date,  this  Debenture  shall be
      convertible  into shares of Common  Stock at the option of the Holder,  in
      whole  or in part at any  time  and  from  time  to time  (subject  to the
      limitations  on  conversion  set forth in Section  4(a)(ii)  hereof).  The
      Holder shall effect  conversions  by delivering to the Company the form of
      conversion  notice  attached  hereto as Annex A (a  "Conversion  Notice"),
      specifying  therein the principal amount of Debentures to be converted and
      the date on which such conversion is to be effected (a "Conversion  Date")
      and shall  contain a  completed  schedule in the form of Schedule 1 to the
      Conversion  Notice (as amended on each  Conversion  Date, the  "Conversion
      Schedule") reflecting the remaining principal amount of this Debenture and
      all accrued and unpaid  interest  thereon  subsequent to the conversion at
      issue.  If no  Conversion  Date is specified in a Conversion  Notice,  the
      Conversion Date shall be the date that such Conversion  Notice is provided
      hereunder.  To  effect  conversions  hereunder,  the  Holder  shall not be
      required to  physically  surrender  Debentures  to the Company  unless the
      entire   principal  amount  of  this  Debenture  has  been  so  converted.
      Conversions  hereunder  shall have the effect of lowering the  outstanding
      principal  amount of this Debenture  plus all accrued and unpaid  interest
      thereon in an amount equal to the  applicable  conversion,  which shall be
      evidenced by entries set forth in the Conversion Schedule.

                                       6
<PAGE>

      The Holder and the Company shall maintain records showing the principal
      amount converted and the date of such conversions. The Company shall
      deliver any objection to the figures represented in the Conversion
      Schedules within 3 Business Day of receipt of such notice and, in the
      event any such objections are determined to be correct, the period for
      delivering a certificate upon such conversion shall not be deemed to have
      commenced until such objections have been resolved, provided, however, as
      to any part of a conversion not in dispute, the Company shall timely meet
      its delivery obligations hereunder. The Holder and any assignee, by
      acceptance of this Debenture, acknowledge and agree that, by reason of the
      provisions of this paragraph, following conversion of a portion of this
      Debenture, the unpaid and unconverted principal amount of this Debenture
      may be less than the amount stated on the face hereof.

            (ii) Certain Conversion Restrictions.

                  (A) A Holder may not convert this Debenture to the extent such
            conversion would result in the Holder, together with its Affiliates,
            beneficially owning (as determined in accordance with Section 13(d)
            of the Exchange Act and the rules promulgated thereunder
            ("Beneficially Owning") in excess of 4.999% of the then issued and
            outstanding shares of Common Stock. The Company shall not issue
            shares of Common Stock to the Holder hereunder (including, but not
            limited to, as payment of interest, in lieu of payment for Monthly
            Redemptions or pursuant to a Force Conversion Notice) to the extent
            such issuance would result in the Holder, together with its
            Affiliates, Beneficially Owning shares of Common Stock in excess of
            9.999% of the then issued and outstanding shares of Common Stock
            (without including, for purposes of such 9.999% provision, any
            shares which may be issuable upon conversion of any Debentures held
            by the Holder or its Affiliates or exercise of any Warrants held by
            the Holder or its Affiliates). The Holder shall be entitled to rely
            on the Company's public filing with respect to the number of shares
            of Common Stock which are then issued and outstanding, and the
            Holder may inquire of the Company's Chief Financial Officer to
            obtain a more current number, which shall be provided within 2
            Business Days of written request therefore. To ensure compliance
            with this restriction, the Holder will be deemed to represent to the
            Company each time it delivers a Conversion Notice that such
            Conversion Notice has not violated the restrictions set forth in
            this paragraph. Additionally, upon the Company exercising its right
            to issue shares of Common Stock under this Debenture, if the Holder
            has determined that such issuance will violate the restrictions set
            forth in this paragraph, the Holder shall promptly notify the
            Company of such violation and, if requested, provide such evidence
            thereof as is reasonably requested by the Company. In the event
            Holder does not so notify the

                                       7
<PAGE>

            Company, the Company shall be entitled to presume that such issuance
            would not violate the restrictions set forth in this paragraph and
            to issue such shares of Common Stock. If the Holder has delivered a
            Conversion Notice for a principal amount of Debentures that, without
            regard to any other shares that the Holder or its affiliates may
            beneficially own, would result in the issuance in excess of the
            permitted amount hereunder, the Company shall notify the Holder of
            this fact and shall honor the conversion for the maximum principal
            amount permitted to be converted on such Conversion Date in
            accordance with the periods described in Section 4(b) and, at the
            option of the Holder, either retain any principal amount tendered
            for conversion in excess of the permitted amount hereunder for
            future conversions or return such excess principal amount to the
            Holder. In the event of a merger or consolidation of the Company
            with or into another Person, this paragraph shall not apply with
            respect to a determination of the number of shares of common stock
            issuable upon conversion in full of the Debentures if such
            determination is necessary to establish the Securities or other
            assets which the holder of Common Stock shall be entitled to receive
            upon the effectiveness of such merger or consolidation. The
            provisions of this Section 4(a)(ii)(A) may be waived by the Holder
            at the election of the Holder upon not less than 61 days' prior
            notice to the Company, and the provisions of this Section
            4(a)(ii)(A) shall continue to apply until such 61st day (or such
            later date, as determined by the Holder, as may be specified in such
            notice of waiver). No conversion of this Debenture in violation of
            this Section 4(a)(ii)(A) but otherwise in accordance with this
            Debenture shall affect the status of the Underlying Shares as
            validly issued, fully-paid and nonassessable.

                  (B) If the Company has not obtained Shareholder Approval (as
            defined below), if required by the applicable rules and regulations
            of the Principal Market (or any successor entity), then the Company
            may not issue upon conversion of the Debentures, in the aggregate,
            in excess of (i) 19.999% of the number of shares of Common Stock
            outstanding on the Trading Day immediately preceding the Original
            Issue Date, (ii) less any shares of Common Stock issued as payment
            of interest, in connection with any redemption of any Debentures, or
            to be issued upon exercise of the Warrants issued to Holders of the
            Debentures pursuant to the Purchase Agreement or upon exercise of
            the warrants issued to David Enzer for his services in connection
            with the transactions contemplated under the Purchase Agreement
            (such number of shares, the "Issuable Maximum"). Each Holder shall
            be entitled to a portion of the Issuable Maximum equal to the
            quotient obtained by dividing (x) the aggregate principal amount of
            the Debenture(s) issued and sold to such Holder by (y) the aggregate
            principal amount of all Debentures issued and sold by the Company.
            If any Holder shall no longer hold

                                       8
<PAGE>

            Debentures, then such Holder's remaining portion of the Issuable
            Maximum shall be allocated pro-rata among the remaining Holders. If
            on any Conversion Date: (A) the applicable Set Price then in effect
            is such that the shares issuable under this Debenture on any
            Conversion Date together with the aggregate number of shares of
            Common Stock that would then be issuable upon conversion in full of
            all then outstanding Debentures would exceed the Issuable Maximum,
            and (B) Shareholder Approval shall not have been obtained, then the
            Company shall issue to the Holder requesting a conversion a number
            of shares of Common Stock equal to such Holder's pro-rata portion
            (which shall be calculated pursuant to the terms hereof) of the
            Issuable Maximum and, with respect to the remainder of the aggregate
            principal amount of the Debentures (including any accrued interest)
            then held by such Holder for which a conversion in accordance with
            the applicable conversion price would result in an issuance of
            shares of Common Stock in excess of such Holder's pro-rata portion
            (which shall be calculated pursuant to the terms hereof) of the
            Issuable Maximum (the "Excess Principal"), the Company shall be
            prohibited from converting such Excess Principal, and shall notify
            the Holder of the reason therefor. This Debenture shall thereafter
            be unconvertible until and unless Shareholder Approval is
            subsequently obtained or is otherwise not required, but this
            Debenture shall otherwise remain in full force and effect. The
            Company and the Holder understand and agree that shares of Common
            Stock issued to and then held by the Holder as a result of
            conversions of Debentures shall not be entitled to cast votes on any
            resolution to obtain Shareholder Approval pursuant hereto. For
            clarity, the failure of the Company to actually obtain Shareholder
            Approval shall not be a breach of covenant or Event of Default under
            Section 3 of this Debenture, provided, that any issuance of
            securities which results in an adjustment to the Set Price (other
            than pursuant to Section 4(c)(ii)(A)) without the Company having
            previously sought Shareholder Approval as set forth in the Purchase
            Agreement shall be a breach of covenant in the Purchase Agreement
            and an Event of Default under Section 3.

            (iii) Underlying Shares Issuable Upon Conversion and Pursuant to
      Interest.

                  (A) Conversion of Principal Amount. The number of shares of
            Common Stock issuable upon a conversion shall be determined by the
            quotient obtained by dividing (x) the outstanding principal amount
            of this Debenture to be converted and (y) the Set Price, and

                  (B) Payment of Interest in Underlying Shares. In the event the
            Company elects to pay the interest due on an Interest Payment Date
            in shares of Common Stock, the number of shares of Common Stock
            issuable

                                       9
<PAGE>

            upon payment of interest under this Debenture shall be the number
            determined by (x) the product of (I) the outstanding principal
            amount of this Debenture to be converted and (II) the product of
            (aa) the quotient obtained by dividing 7.5% by 360 and (bb) the
            number of days for which such principal amount was outstanding,
            divided by (y) the applicable Interest Conversion Rate.

                  (C) Notwithstanding anything to the contrary contained herein,
            if with respect to any Conversion Date:

                        (1) the number of shares of Common Stock at the time
                  authorized, unissued and unreserved for all purposes, or held
                  as treasury stock, is insufficient to honor such conversion;

                        (2) the Common Stock shall fail to be listed or quoted
                  for trading on a Principal Market; or

                        (3) the Company has failed to deliver certificates to
                  the Holder on or before the fifth Trading Day after such
                  Conversion Date pursuant to and in accordance with Section 4,

            and, with respect to such delivery, no election has been made by the
            Holder pursuant to Section 3(b), Section 4(b)(i), Section 4(b)(ii)
            or Section 4(b)(iii), then, at the written election of the Holder,
            the Company, in lieu of delivering shares of Common Stock pursuant
            to this Section 4, shall deliver, within three Trading Days of such
            election, an amount in cash equal to the product of the number of
            shares of Common Stock otherwise deliverable to the Holder in
            connection with such Conversion Date and the highest VWAP during the
            period commencing on the Conversion Date and ending on the Trading
            Day prior to the date such payment is made. In the event the Holder
            elects to receive payment pursuant to this Section 4(a)(iii)(C),
            then the Holder shall not be entitled to declare an Event of Default
            pursuant to Section 3 hereof with respect to such failure to deliver
            the certificates; provided, however, it being understood that this
            provision does not preclude the Holder from declaring an Event of
            Default for the Company failing to pay any such amounts in the time
            period set forth above.

      (b) (i) Not later than five Trading Days after any Conversion Date, the
      Company will deliver to the Holder (A) a certificate or certificates for
      the Shares of Common Stock which shall be free of restrictive legends and
      trading restrictions (other than those required by the Purchase Agreement)
      representing the number of shares of Common Stock being acquired upon the
      conversion of Debentures and (B)

                                       10
<PAGE>

      a bank check in the amount of accrued and unpaid interest (if the Company
      has elected to pay accrued interest in cash). The Company shall, upon
      request of the Holder, if available and if allowed under applicable
      securities laws, use its best efforts to deliver any certificate or
      certificates required to be delivered by the Company under this Section
      electronically through the Depository Trust Corporation or another
      established clearing corporation performing similar functions. If in the
      case of any Conversion Notice such certificate or certificates are not
      delivered to or as directed by the applicable Holder by the fifth Trading
      Day after a Conversion Date, the Holder shall be entitled by written
      notice to the Company at any time on or before its receipt of such
      certificate or certificates thereafter, to rescind such conversion, in
      which event the Company shall immediately return the certificates
      representing the principal amount of Debentures tendered for conversion.

      (ii) If the Company fails for any reason to deliver to the Holder such
      certificate or certificates pursuant to and in accordance with Section 4
      by the fifth Trading Day after the Conversion Date and, with respect to
      such delivery, no prior election has been made by the Holder pursuant to
      Section 3(b), Section 4(a)(iii)(C) or Section 4(b)(iii) and such Holder
      does not rescind such conversion pursuant to Section 4(b)(i), the Company
      shall pay to such Holder, in cash, as liquidated damages and not as a
      penalty, for each $5,000 of principal amount being converted, $50 per
      Trading Day (increasing to $100 per Trading Day after 3 Trading Days) for
      each Trading Day after such fifth Trading Day until such certificates are
      delivered. Nothing herein shall limit a Holder's right to pursue actual
      damages or declare an Event of Default pursuant to Section 3 herein for
      the Company's failure to deliver certificates representing shares of
      Common Stock upon conversion within the period specified therein. The
      Holder shall have the right to pursue all remedies available to it at law
      or in equity including, without limitation, a decree of specific
      performance and/or injunctive relief. The exercise of any such rights
      shall not prohibit the Holders from seeking to enforce damages pursuant to
      any other Section hereof or under applicable law.

      (iii) In addition to any other rights available to the Holder, if the
      Company fails for any reason to deliver to the Holder such certificate or
      certificates pursuant to and in accordance with Section 4 by the fifth
      Trading Day after the Conversion Date, and with respect to such delivery,
      no prior election has been made by the Holder pursuant to Section 3(b),
      Section 4(a)(iii)(C), Section 4(b)(i) or Section 4(b)(ii), if after such
      fifth Trading Day the Holder is required by its brokerage firm to purchase
      (in an open market transaction or otherwise) Common Stock to deliver in
      satisfaction of a sale by such Holder of the Underlying Shares which the
      Holder anticipated receiving upon such conversion (a "Buy-In"), then the
      Company shall (A) pay in cash to the Holder (in addition to any remedies
      available to or elected by the Holder) the amount by which (x) the
      Holder's total purchase price (including brokerage commissions, if any)

                                       11
<PAGE>

      for the Common Stock so purchased exceeds (y) the product of (1) the
      aggregate number of shares of Common Stock that such Holder anticipated
      receiving from the conversion at issue multiplied by (2) the actual sale
      price of the Common Stock at the time of the sale (including brokerage
      commissions, if any) giving rise to such purchase obligation and (B) at
      the option of the Holder, either reissue Debentures in principal amount
      equal to the principal amount of the attempted conversion or deliver to
      the Holder the number of shares of Common Stock that would have been
      issued had the Company timely complied with its delivery requirements
      under Section 4(b)(i). For example, if the Holder purchases Common Stock
      having a total purchase price of $11,000 to cover a Buy-In with respect to
      an attempted conversion of Debentures with respect to which the actual
      sale price of the Underlying Shares at the time of the sale (including
      brokerage commissions, if any) giving rise to such purchase obligation was
      a total of $10,000 under clause (A) of the immediately preceding sentence,
      the Company shall be required to pay the Holder $1,000. The Holder shall
      provide the Company written notice indicating the amounts payable to the
      Holder in respect of the Buy-In. In the event the Holder elects to receive
      payment pursuant to this Section 4(a)(iii)(C), then the Holder shall not
      be entitled to declare an Event of Default pursuant to Section 3 hereof
      with respect to such failure to deliver the certificates; provided,
      however, it being understood that this provision does not preclude the
      Holder from declaring an Event of Default for failure to timely make such
      Buy-In payments.

      (iv) Notwithstanding anything herein to the contrary, if after the
      Effective Date the VWAP for any 15 consecutive Trading Days exceeds the
      then Set Price by more than 200%, the Company may, within 2 Trading Days
      of any such period, deliver a notice to the Holder (a "Forced Conversion
      Notice" and the date such notice is received by the Holder, the "Forced
      Conversion Notice Date") to cause the Holder to immediately convert all or
      part of the then outstanding principal amount of Debentures pursuant to
      Section 4(a)(i). The Company may only effect a Forced Conversion Notice if
      each of the following shall be true: (i) there is an effective Underlying
      Shares Registration Statement pursuant to which the Holder is permitted to
      utilize the prospectus thereunder to resell all of the Underlying Shares
      issued to the Holder and all of the Underlying Shares as are issuable to
      the Holder upon conversion in full of this Debenture subject to the Forced
      Conversion Notice (and the Company has not been notified that such
      effectiveness will be interrupted in the foreseeable future), (ii) the
      Common Stock is listed for trading on a Principal Market (and the Company
      has not been notified that trading of the Common Stock on a Principal
      Market will be interrupted in the foreseeable future), (iii) all
      liquidated damages and other amounts owing in respect of the Debentures
      and Underlying Shares shall have been paid or will, concurrently with the
      issuance of the Underlying Shares, be paid; (iv) there is a sufficient
      number of authorized but unissued and otherwise unreserved shares of
      Common Stock for the issuance of all the Underlying

                                       12
<PAGE>

      Shares as are issuable to the Holder upon conversion in full of the
      Debentures subject to the Forced Conversion Notice; (v) no Event of
      Default nor any event that with the passage of time would constitute an
      Event of Default has occurred and is continuing; (vi) such issuance would
      be permitted in full without violating the limitations set forth in
      clauses (A) or (B) of Section 4(a)(ii) and (vii) no public announcement of
      a pending or proposed Change of Control Transaction or Fundamental
      Transaction has occurred that has not been consummated.

      (c) (i) Set Price. The conversion price in effect on any Conversion Date
      shall be equal to $____(5) (subject to adjustment as provided herein)(the
      "Set Price").

            (ii) Adjustments of Set Price.

                  (A) Stock Splits, etc. The number and kind of securities
            issuable upon the conversion of this Debenture and the Set Price
            shall be subject to adjustment from time to time upon the happening
            of any of the events set forth below. In case the Company shall (i)
            pay a dividend in shares of Common Stock or make a distribution in
            shares of Common Stock to holders of its outstanding Common Stock,
            (ii) subdivide its outstanding shares of Common Stock into a greater
            number of shares, (iii) combine its outstanding shares of Common
            Stock into a smaller number of shares of Common Stock, or (iv) issue
            any shares of its capital stock in a reclassification of the Common
            Stock, then the number of Underlying Shares issuable upon conversion
            of this Debenture immediately prior thereto shall be adjusted so
            that the Holder shall be entitled to receive the kind and number of
            Underlying Shares or other securities of the Company which it would
            have owned or have been entitled to receive had such Debenture been
            converted in advance thereof. Upon each such adjustment of the kind
            and number of Underlying Shares or other securities of the Company
            which are issuable hereunder, the Holder shall thereafter be
            entitled to purchase the number of Underlying Shares or other
            securities resulting from such adjustment at a Set Price per
            Underlying Share or other security obtained by multiplying the Set
            Price in effect immediately prior to such adjustment by the number
            of Underlying Shares issuable pursuant hereto immediately prior to
            such adjustment and dividing by the number of Underlying Shares or
            other securities of the Company resulting from such adjustment. An
            adjustment made pursuant to this paragraph shall become effective
            immediately after the effective date of such event retroactive to
            the record date, if any, for such event.

----------
5   112% of the Closing Price on the applicable Closing Date.

                                       13
<PAGE>

                  (B) Future Issuance Anti-Dilution Provisions. Until this
            Debenture is not longer outstanding, if and whenever the Company
            issues or sells, or in accordance with this Section 4(c)(ii)(B)
            hereof is deemed to have issued or sold, any shares of Common Stock
            for an effective consideration per share of Common Stock less than
            89% of the then Set Price or for no consideration (such lower price,
            the "Base Share Price" and such issuances collectively, a "Dilutive
            Issuance"), then, the Set Price shall be reduced to equal 112% of
            the Base Share Price. Such adjustment shall be made whenever such
            shares of Common Stock are issued or deemed to have been issued in
            accordance with this Section 4(c)(ii)(B). For purposes of
            determining the adjusted Set Price under this Section 4(c)(ii)(B)
            hereof, the following will be applicable:

                        (1) Issuance of Rights or Options. If the Company in any
                  manner issues or grants any warrants, rights or options,
                  whether or not immediately exercisable, to subscribe for or to
                  purchase Common Stock or other securities exercisable,
                  convertible into or exchangeable for Common Stock
                  ("Convertible Securities") (such warrants, rights and options
                  to purchase Common Stock or Convertible Securities are
                  hereinafter referred to as "Options") and the effective price
                  per share for which Common Stock is issuable upon the exercise
                  of such Options is less than the Set Price ("Below Base Price
                  Options"), then the maximum total number of shares of Common
                  Stock issuable upon the exercise of all such Below Base Price
                  Options (assuming full exercise, conversion or exchange of
                  Convertible Securities, if applicable) will, as of the date of
                  the issuance or grant of such Below Base Price Options, be
                  deemed to be outstanding and to have been issued and sold by
                  the Company for such price per share and the maximum
                  consideration payable to the Company upon such exercise
                  (assuming full exercise, conversion or exchange of Convertible
                  Securities, if applicable) will be deemed to have been
                  received by the Company. For purposes of the preceding
                  sentence, the "effective price per share for which Common
                  Stock is issuable upon the exercise of such Below Base Price
                  Options" is determined by dividing (i) the total amount, if
                  any, received or receivable by the Company as consideration
                  for the issuance or granting of all such Below Base Price
                  Options, plus the minimum aggregate amount of additional
                  consideration, if any, payable to the Company upon the
                  exercise of all such Below Base Price Options, plus, in the
                  case of Convertible Securities issuable upon the exercise of
                  such Below Base Price Options, the minimum aggregate amount of
                  additional consideration payable upon the exercise, conversion
                  or exchange

                                       14
<PAGE>

                  thereof at the time such Convertible Securities first become
                  exercisable, convertible or exchangeable, by (ii) the maximum
                  total number of shares of Common Stock issuable upon the
                  exercise of all such Below Base Price Options (assuming full
                  conversion of Convertible Securities, if applicable). No
                  further adjustment to the Set Price will be made upon the
                  actual issuance of such Common Stock upon the exercise of such
                  Below Base Price Options or upon the exercise, conversion or
                  exchange of Convertible Securities issuable upon exercise of
                  such Below Base Price Options.

                        (2) Issuance of Convertible Securities. If the Company
                  in any manner issues or sells any Convertible Securities,
                  whether or not immediately convertible (other than where the
                  same are issuable upon the exercise of Options) and the
                  effective price per share for which Common Stock is issuable
                  upon such exercise, conversion or exchange is less than the
                  Set Price, then the maximum total number of shares of Common
                  Stock issuable upon the exercise, conversion or exchange of
                  all such Convertible Securities will, as of the date of the
                  issuance of such Convertible Securities, be deemed to be
                  outstanding and to have been issued and sold by the Company
                  for such price per share and the maximum consideration payable
                  to the Company upon such exercise (assuming full exercise,
                  conversion or exchange of Convertible Securities, if
                  applicable) will be deemed to have been received by the
                  Company. For the purposes of the preceding sentence, the
                  "effective price per share for which Common Stock is issuable
                  upon such exercise, conversion or exchange" is determined by
                  dividing (i) the total amount, if any, received or receivable
                  by the Company as consideration for the issuance or sale of
                  all such Convertible Securities, plus the minimum aggregate
                  amount of additional consideration, if any, payable to the
                  Company upon the exercise, conversion or exchange thereof at
                  the time such Convertible Securities first become exercisable,
                  convertible or exchangeable, by (ii) the maximum total number
                  of shares of Common Stock issuable upon the exercise,
                  conversion or exchange of all such Convertible Securities. No
                  further adjustment to the Set Price will be made upon the
                  actual issuance of such Common Stock upon exercise, conversion
                  or exchange of such Convertible Securities.

                        (3) Change in Option Price or Conversion Rate. If there
                  is a change at any time in (i) the amount of additional
                  consideration payable to the Company upon the exercise of any
                  Options; (ii) the amount of additional consideration, if any,
                  payable to the Company

                                       15
<PAGE>

                  upon the exercise, conversion or exchange of any Convertible
                  Securities; or (iii) the rate at which any Convertible
                  Securities are convertible into or exchangeable for Common
                  Stock (in each such case, other than under or by reason of
                  provisions designed to protect against dilution), the Set
                  Price in effect at the time of such change will be readjusted
                  to the Set Price which would have been in effect at such time
                  had such Options or Convertible Securities still outstanding
                  provided for such changed additional consideration or changed
                  conversion rate, as the case may be, at the time initially
                  granted, issued or sold.

                        (4) Calculation of Consideration Received. If any Common
                  Stock, Options or Convertible Securities are issued, granted
                  or sold for cash, the consideration received therefor for
                  purposes of this Debenture will be the amount received by the
                  Company therefor, before deduction of reasonable commissions,
                  underwriting discounts or allowances or other reasonable
                  expenses paid or incurred by the Company in connection with
                  such issuance, grant or sale. In case any Common Stock,
                  Options or Convertible Securities are issued or sold for a
                  consideration part or all of which shall be other than cash,
                  the amount of the consideration other than cash received by
                  the Company will be the fair market value of such
                  consideration, except where such consideration consists of
                  securities, in which case the amount of consideration received
                  by the Company will be the fair market value (closing bid
                  price, if traded on any market) thereof as of the date of
                  receipt. In case any Common Stock, Options or Convertible
                  Securities are issued in connection with any merger or
                  consolidation in which the Company is the surviving
                  corporation, the amount of consideration therefor will be
                  deemed to be the fair market value of such portion of the net
                  assets and business of the non-surviving corporation as is
                  attributable to such Common Stock, Options or Convertible
                  Securities, as the case may be. The fair market value of any
                  consideration other than cash or securities will be determined
                  in good faith by an investment banker or other appropriate
                  expert of national reputation selected by the Company and
                  reasonably acceptable to the holder hereof, with the costs of
                  such appraisal to be borne by the Company.

                        (5) Exceptions. Notwithstanding the foregoing, no
                  adjustment will be made under this paragraph (c) in respect of
                  the issuance of (1) shares of Common Stock or Options to
                  employees, consultants, advisors, officers or directors of the
                  Company pursuant

                                       16
<PAGE>

                  to any stock or option plan duly adopted by a majority of the
                  non-employee members of the Board of Directors of the Company
                  or a majority of the members of a committee of non-employee
                  directors established for such purpose, (2) securities upon
                  the exercise of, or in connection with the payment of interest
                  on or redemption of, the Debentures or any Debentures of this
                  series or of any other series or security issued by the
                  Company in connection with the offer and sale of this
                  Company's securities pursuant to the Purchase Agreement, or
                  (3) securities upon the exercise of or conversion of any
                  convertible securities, options or warrants issued and
                  outstanding on the Original Issue Date, provided that the
                  securities have not been amended since the date of the
                  Purchase Agreement, (4) securities in connection with
                  acquisitions or strategic investments (including, without
                  limitation, any licensing or distribution arrangements), the
                  primary purpose of which is not to raise capital, or (5)
                  securities to financial institutions or lessors in connection
                  with commercial credit arrangements, equipment financings or
                  similar transactions, where the principal consideration for
                  such transactions not the issuance of such securities.

                  (C) Minimum Adjustment of Set Price. No adjustment of the Set
            Price shall be made in an amount of less than 1% of the Set Price in
            effect at the time such adjustment is otherwise required to be made,
            but any such lesser adjustment shall be carried forward and shall be
            made at the time and together with the next subsequent adjustment
            which, together with any adjustments so carried forward, shall
            amount to not less than 1% of such Set Price.

                  (D) All calculations under this Section 4 shall be made to the
            nearest cent or the nearest 1/100th of a share, as the case may be.
            For purposes of this Section 4.

                  (E) If, in any case, the total number of shares of Common
            Stock issuable upon exercise of any Option or upon exercise,
            conversion or exchange of any Convertible Security is not, in fact,
            issued and the rights to exercise such Option or to exercise,
            convert or exchange such Convertible Security shall have expired or
            terminated, the Set Price then in effect will be readjusted to the
            Set Price which would have been in effect at the time of such
            expiration or termination had such Option or Convertible Securities,
            to the extent outstanding immediately prior to such expiration or
            termination (other than in respect of the actual number of shares of
            Common Stock issued upon exercise or conversion thereof), never been
            issued; provided, however,

                                       17
<PAGE>

            prior to such adjustment, the Company shall have notified the Holder
            at least 5 Trading Days prior to the date such adjustment occurs.

                  (F) The Company agrees that it is prohibited from entering
            into any Dilutive Issuance which would result in any adjustment to
            the Set Price under this Section 4(c)(ii)(B) to the extent the
            Holder would not be able to convert the entire amount outstanding of
            this Debenture and the Warrants held by such Holder without
            violating Section 4(a)(ii)(B). The Company shall promptly mail to
            each Holder a notice setting forth the Set Price after such
            adjustment and setting forth a brief statement of the facts
            requiring such adjustment.

            (iii) Notification. If (A) the Company shall declare a dividend (or
      any other distribution) on the Common Stock; (B) the Company shall declare
      a special nonrecurring cash dividend on or a redemption of the Common
      Stock; (C) the Company shall authorize the granting to all holders of the
      Common Stock rights or warrants to subscribe for or purchase any shares of
      capital stock of any class or of any rights; (D) the approval of any
      stockholders of the Company shall be required in connection with any
      reclassification of the Common Stock, any consolidation or merger to which
      the Company is a party, any sale or transfer of all or substantially all
      of the assets of the Company, of any compulsory share exchange whereby the
      Common Stock is converted into other securities, cash or property; (E) the
      Company shall authorize the voluntary or involuntary dissolution,
      liquidation or winding up of the affairs of the Company; then, in each
      case, the Company shall cause to be filed at each office or agency
      maintained for the purpose of conversion of the Debentures, and shall
      cause to be mailed to the Holders at their last addresses as they shall
      appear upon the stock books of the Company, at least 20 calendar days
      prior to the applicable record or effective date hereinafter specified, a
      notice stating (x) the date on which a record is to be taken for the
      purpose of such dividend, distribution, redemption, rights or warrants, or
      if a record is not to be taken, the date as of which the holders of the
      Common Stock of record to be entitled to such dividend, distributions,
      redemption, rights or warrants are to be determined or (y) the date on
      which such reclassification, consolidation, merger, sale, transfer or
      share exchange is expected to become effective or close, and the date as
      of which it is expected that holders of the Common Stock of record shall
      be entitled to exchange their shares of the Common Stock for securities,
      cash or other property deliverable upon such reclassification,
      consolidation, merger, sale, transfer or share exchange; provided, that
      the failure to mail such notice or any defect therein or in the mailing
      thereof shall not affect the validity of the corporate action required to
      be specified in such notice. Holders are entitled to convert Debentures
      during the 20-day period commencing the date of such notice to the
      effective date of the event triggering such notice.

                                       18
<PAGE>

      (iv) Fundamental Transactions/Change of Control. If, at any time while
      this Debenture is outstanding, (A) the Company effects any merger or
      consolidation of the Company with or into another Person, (B) the Company
      effects any sale of all or substantially all of its assets in one or a
      series of related transactions, (C) any tender offer or exchange offer
      (whether by the Company or another Person) is completed pursuant to which
      holders of Common Stock are permitted to tender or exchange their shares
      for other securities, cash or property, or (D) the Company effects any
      reclassification of the Common Stock or any compulsory share exchange
      pursuant to which the Common Stock is effectively converted into or
      exchanged for other securities, cash or property (in any such case, a
      "Fundamental Transaction"), then upon any subsequent conversion of this
      Debenture, the Holder shall have the right to receive, for each Underlying
      Share that would have been issuable upon such conversion absent such
      Fundamental Transaction, the same kind and amount of securities, cash or
      property as it would have been entitled to receive upon the occurrence of
      such Fundamental Transaction if it had been, immediately prior to such
      Fundamental Transaction, the holder of one share of Common Stock (the
      "Alternate Consideration"). For purposes of any such conversion, the
      determination of the Set Price shall be appropriately adjusted to apply to
      such Alternate Consideration based on the amount of Alternate
      Consideration issuable in respect of one share of Common Stock in such
      Fundamental Transaction, and the Company shall apportion the Set Price
      among the Alternate Consideration in a reasonable manner reflecting the
      relative value of any different components of the Alternate Consideration.
      If holders of Common Stock are given any choice as to the securities, cash
      or property to be received in a Fundamental Transaction, then the Holder
      shall be given the same choice as to the Alternate Consideration it
      receives upon any conversion of this Debenture following such Fundamental
      Transaction. To the extent necessary to effectuate the foregoing
      provisions, any successor to the Company or surviving entity in such
      Fundamental Transaction shall issue to the Holder a new Debenture
      consistent with the foregoing provisions and evidencing the Holder's right
      to convert such Debenture into Alternate Consideration. The terms of any
      agreement pursuant to which a Fundamental Transaction is effected shall
      include terms requiring any such successor or surviving entity to comply
      with the provisions of this paragraph (c) and insuring that this Debenture
      (or any such replacement security) will be similarly adjusted upon any
      subsequent transaction analogous to a Fundamental Transaction. In the
      event of a Change of Control Transaction, including any Fundamental
      Transaction which constitutes or results in a Change of Control
      Transaction, then at the request of the Holder delivered before the 90th
      day after such Fundamental Transaction, the Company (or any such successor
      or surviving entity) will purchase the Debenture from the Holder for a
      purchase price, payable in cash within five Trading Days after such
      request (or, if later, on the effective date of the Fundamental
      Transaction), equal to 100% of the remaining unconverted principal amount
      of this

                                       19
<PAGE>

      Debenture on the date of such request, plus all accrued and unpaid
      interest thereon, plus all other accrued and unpaid amounts due hereunder.

      (d) The Company covenants that it will at all times reserve and keep
available out of its authorized and unissued shares of Common Stock an amount
equal to 130% of the Actual Minimum, free from preemptive rights or any other
actual contingent purchase rights of persons other than the Holders. The Company
covenants that all shares of Common Stock that shall be so issuable shall, upon
issuance in accordance with the terms of the Transaction Documents, be duly and
validly authorized, issued and fully paid, nonassessable and, if the Underlying
Shares Registration Statement has been declared effective under the Securities
Act, registered for public sale in accordance with such Underlying Shares
Registration Statement.

      (e) Upon a conversion hereunder the Company shall not be required to issue
stock certificates representing fractions of shares of the Common Stock, but may
if otherwise permitted, make a cash payment in respect of any final fraction of
a share based on the VWAP at such time. If the Company elects not, or is unable,
to make such a cash payment, the Holder shall be entitled to receive, in lieu of
the final fraction of a share, one whole share of Common Stock.

      (f) The issuance of certificates for shares of the Common Stock on
conversion of the Debentures shall be made without charge to the Holders thereof
for any documentary stamp or similar taxes that may be payable in respect of the
issue or delivery of such certificate, provided that the Company shall not be
required to pay any tax that may be payable in respect of any transfer involved
in the issuance and delivery of any such certificate upon conversion in a name
other than that of the Holder of such Debentures so converted and the Company
shall not be required to issue or deliver such certificates unless or until the
person or persons requesting the issuance thereof shall have paid to the Company
the amount of such tax or shall have established to the satisfaction of the
Company that such tax has been paid.

      (g) Any and all notices or other communications or deliveries to be
provided by the Holders hereunder, including, without limitation, any Conversion
Notice, shall be in writing and delivered personally, by facsimile, sent by a
nationally recognized overnight courier service or sent by certified or
registered mail, postage prepaid, addressed to the Company, at the address set
forth above, FACSIMILE NUMBER (617) 928-0821, ATTN: STEPHEN D. CHUBB WITH A COPY
TO TESTA, HURWITZ & THIBEAULT, LLP, 125 HIGH STREET, BOSTON, MASSACHUSETTS
02110, FACSIMILE NUMBER (617) 248-7100, ATTN: RUFUS C. KING, or such other
address or facsimile number as the Company may specify for such purposes by
notice to the Holders delivered in accordance with this Section. Any and all
notices or other communications or deliveries to be provided by the Company
hereunder shall be in writing and delivered personally, by facsimile, sent by a
nationally recognized overnight courier

                                       20
<PAGE>

service or sent by certified or registered mail, postage prepaid, addressed to
each Holder at the facsimile telephone number or address of such Holder
appearing on the books of the Company, or if no such facsimile telephone number
or address appears, at the principal place of business of the Holder. Any notice
or other communication or deliveries hereunder shall be deemed given and
effective on the earliest of (i) the date of transmission, if such notice or
communication is delivered via facsimile at the facsimile telephone number
specified in this Section prior to 5:30 p.m. (New York City time), (ii) the date
after the date of transmission, if such notice or communication is delivered via
facsimile at the facsimile telephone number specified in this Section later than
5:30 p.m. (New York City time) on any date and earlier than 11:59 p.m. (New York
City time) on such date, (iii) four days after deposit in the United States
mail, (iv) the Business Day following the date of mailing, if sent by nationally
recognized overnight courier service, or (v) upon actual receipt by the party to
whom such notice is required to be given. NOTWITHSTANDING THE FOREGOING, ANY
CONVERSION NOTICES SHALL BE REQUIRED TO ALSO BE DELIVERED BY FACSIMILE ON THE
DATE SET FORTH IN SUCH CONVERSION NOTICE.

Section 5. Redemption.

      (a) Optional Redemption. Subject to the provisions of this Section 5, the
Company may, at any time, deliver a notice to the Holders (an "Optional
Redemption Notice" and the date such notice is deemed delivered hereunder, the
"Optional Redemption Notice Date") of its irrevocable election to redeem all,
but not less than all, of the then outstanding Debentures held by the Holder,
for an amount, in cash, equal to the Optional Redemption Amount on a date
designated by the Company in the Optional Redemption Notice, such date to be at
least 30 Trading Days following the Optional Redemption Notice Date (such date,
the "Optional Redemption Date" and such redemption, the "Optional Redemption").
The Optional Redemption Amount is due in full on the Optional Redemption Date.
The Company may only effect an Optional Redemption if from the Optional
Redemption Notice Date through to the Optional Redemption Date, each of the
following shall be true: (i) there is an effective Registration Statement
pursuant to which the Holder is permitted to utilize the prospectus thereunder
to resell all of the Underlying Shares issued to the Holder and all of the
Underlying Shares as are issuable to the Holder upon conversion in full of the
Debenture subject to such Optional Redemption (and the Company has not been
notified that such effectiveness will be interrupted in the foreseeable future),
(ii) the Common Stock is listed for trading on a Principal Market (and the
Company has not been notified that trading of the Common Stock on the Principal
Market will be interrupted in the foreseeable future), (iii) all liquidated
damages and other amounts owing in respect of the Debenture shall have been paid
or will, concurrently with the delivery of the Optional Redemption Notice, be
paid; (iv) there is a sufficient number of authorized but unissued and otherwise
unreserved shares of Common Stock for the issuance of all of the shares then
issuable pursuant to the Transaction Documents as of such date; (v) conversion
of this Debenture would be permitted in full without violating the limitations
set forth in Section

                                       21
<PAGE>

4(a)(ii)(B); (vi) no Event of Default nor any event that with the passage of
time would constitute an Event of Default has occurred and is continuing; and
(vii) no public announcement of a pending or proposed Change of Control
Transaction or Fundamental Transaction has occurred that has not been
consummated.. If any of the foregoing conditions shall cease to be satisfied at
any time during the required period, then the Holder may elect to nullify the
Optional Redemption Notice in which case the Optional Redemption Notice shall be
null and void, ab initio. The Holders may convert, pursuant to Section 4 hereof,
any shares of Debentures subject to an Optional Redemption at any time prior to
the date that the Optional Redemption Amount and all amounts owing thereon are
due and paid in full. The Company covenants and agrees that it will honor all
Conversion Notices tendered from the time of delivery of the Optional Redemption
Notice through the date all amounts owing thereon are due and paid in full.

      (b) Monthly Redemption. On each Monthly Redemption Date, the Company shall
redeem each Holder's Pro-Rata Portion of the Monthly Redemption Amount plus
accrued but unpaid interest, the sum of all liquidated damages and any other
amounts then owing to such Holder in respect of the Debenture. "Pro Rata
Portion" is the ratio of (x) the principal amount of this Debenture on the
Issuance Date and (y) the sum of the aggregate original principal amounts of the
Debentures issued to all Holders on the Issuance Date. If any Holder shall no
longer holds Debentures, then the Pro Rata Portion shall be recalculated to
exclude such Holder's principal amount from clause (y) above. The Monthly
Redemption Amount due on each Monthly Redemption Date shall, except as provided
in this Section, be paid in cash. As to any Monthly Redemption and upon 20
Trading Days' prior written irrevocable notice, in lieu of a cash redemption
payment the Company may elect to pay 100% of a Monthly Redemption in Underlying
Shares based on a conversion price equal to 90% of the average of the 20 VWAPs
immediately prior to the applicable Monthly Redemption Date (subject to
adjustment for any stock dividend, stock split, stock combination or other
similar event affecting the Common Stock during such 20 Trading Day period) (the
"Monthly Conversion Price"); provided, however, that the Company may not pay the
Monthly Redemption Amount in Underlying Shares unless, on the Monthly Redemption
Date and during the 20 Trading Day period immediately prior thereto, (i) there
is an effective Registration Statement pursuant to which the Holder is permitted
to utilize the prospectus thereunder to resell all of the Underlying Shares
issued to the Holder and all of the Underlying Shares as are issuable to the
Holder upon conversion in full of the Debenture subject to such Monthly
Redemption (and the Company has not been notified that such effectiveness will
be interrupted in the foreseeable future), (ii) the Common Stock is listed for
trading on a Principal Market (and the Company has not been notified that
trading of the Common Stock on the Principal Market will be interrupted in the
foreseeable future), (iii) on or prior to the 20th Trading Day prior to such
Monthly Redemption Date, the Company irrevocably notifies the Holder that it
will issue Underlying Shares in lieu of cash; (iv) all liquidated damages and
other amounts owing in respect of the Debenture shall have been paid or will,
concurrently with the issuance of the Underlying Shares, be paid; (v) there is a

                                       22
<PAGE>

sufficient number of authorized but unissued and otherwise unreserved shares of
Common Stock for the issuance of all of the shares then issuable pursuant to the
Transaction Documents as of such date; (vi) such issuance would be permitted in
full without violating the limitations set forth in Section 4(a)(ii)(A) or (B);
(vii) no Event of Default nor any event that with the passage of time would
constitute an Event of Default has occurred and is continuing; and (viii) no
public announcement of a pending or proposed Change of Control Transaction or
Fundamental Transaction has occurred that has not been consummated. The Holders
may convert, pursuant to Section 4, any principal amount of the Debenture
subject to a Monthly Redemption at any time prior to the date that the Monthly
Redemption Amount and all amounts owing thereon are due and paid in full. The
Company covenants and agrees that it will honor all Conversion Notices tendered
up until such amounts are paid in full.

      (c) Redemption Procedure. The payment of cash and/or issuance of Common
Stock, as the case may be, pursuant to a Monthly Redemption shall be made on the
Monthly Redemption Date and the payment pursuant to an Optional Redemption shall
be made on the Optional Redemption Date. If any portion of the cash payment for
a Monthly Redemption or Optional Redemption shall not be paid by the Company by
the respective due date, interest shall accrue thereon at the rate of 15% per
annum (or the maximum rate permitted by applicable law, whichever is less) until
the payment of the Monthly Redemption Amount or Optional Redemption Amount, as
applicable, plus all amounts owing thereon is paid in full. Alternatively, if
any portion of the Monthly Redemption Amount or Optional Redemption Amount, as
applicable, remains unpaid after such date, the Holders subject to such
redemption may elect, by written notice to the Company given at any time
thereafter, to invalidate ab initio such redemption, notwithstanding anything
herein contained to the contrary, and, with respect the failure to honor an
Optional Redemption only, the Company shall have no further right to exercise
such Optional Redemption Right. Notwithstanding anything to the contrary in this
Section 5, the Company's determination to redeem in cash or shares of Common
Stock shall be applied ratably among the Holders of Debentures issued on the
Issuance Date based upon the principal amount of Debentures initially purchased
by each Holder on such Issuance Date, adjusted upward ratably in the event all
of the shares of Debentures of any Holder issued on such Issuance Date are no
longer outstanding.

      Section 6. Definitions. For the purposes hereof, in addition to the terms
defined elsewhere in this Debenture: (a) capitalized terms not otherwise defined
herein have the meanings given to such terms in the Purchase Agreement, and (b)
the following terms shall have the following meanings:

            "Actual Minimum" shall have the meaning set forth in the Purchase
      Agreement.

            "Business Day" means any day except Saturday, Sunday and any day
      which shall be a federal legal holiday in the United States or a day on
      which banking institutions in the State of New York are authorized or
      required by law or other government action to close.

                                       23
<PAGE>

            "Change of Control Transaction" means the occurrence after the date
      hereof of any of (i) an acquisition after the date hereof by an individual
      or legal entity or "group" (as described in Rule 13d-5(b)(1) promulgated
      under the Exchange Act) of effective control (whether through legal or
      beneficial ownership of capital stock of the Company, by contract or
      otherwise) of in excess of 40% of the voting securities of the Company, or
      (ii) a replacement at one time or within a one year period of more than
      one-half of the members of the Company's board of directors which is not
      approved by a majority of those individuals who are members of the board
      of directors on the date hereof (or by those individuals who are serving
      as members of the board of directors on any date whose nomination to the
      board of directors was approved by a majority of the members of the board
      of directors who are members on the date hereof), or (iii) the execution
      by the Company of an agreement to which the Company is a party or by which
      it is bound, providing for any of the events set forth above in (i) or
      (ii).

            "Commission" means the Securities and Exchange Commission.

            "Common Stock" means the common stock, $0.01 par value per share, of
      the Company and stock of any other class into which such shares may
      hereafter have been reclassified or changed.

            "Conversion Date" shall have the meaning set forth in Section
      4(a)(i).

            "Exchange Act" means the Securities Exchange Act of 1934, as
      amended.

            "Interest Conversion Rate" means 95% of the lesser of (i) the
      average of the 20 VWAPs immediately prior to the applicable Interest
      Payment Date or (ii) the average of the 20 VWAPs immediately prior to the
      date the applicable interest payment shares are issued and delivered if
      after the Interest Payment Date.

            "Issuance Date" shall mean the date of first issuance of this
      Debenture, regardless of the number of transfers of such Debenture and
      regardless of the number of instruments which may be issued to evidence
      such Debenture.

            "Late Fees" shall have the meaning set forth in the second paragraph
      to this Debenture.

            "Mandatory Prepayment Amount" for any Debentures shall equal the sum
      of (i) the greater of: (A) 120% of the principal amount of Debentures to
      be prepaid, plus all accrued and unpaid interest thereon, plus all other
      accrued and unpaid amounts due hereunder, or (B) the principal amount of
      Debentures to be prepaid, plus all accrued and unpaid interest thereon,
      plus all other accrued and unpaid amounts due hereunder, divided by the
      Set Price

                                       24
<PAGE>

      on (x) the date the Mandatory Prepayment Amount is demanded or otherwise
      due or (y) the date the Mandatory Prepayment Amount is paid in full,
      whichever is less, multiplied by the VWAP on (x) the date the Mandatory
      Prepayment Amount is demanded or otherwise due or (y) the date the
      Mandatory Prepayment Amount is paid in full, whichever is greater, and
      (ii) all other amounts, costs, expenses and liquidated damages due in
      respect of such Debentures.

            "Monthly Conversion Price" shall have the meaning set forth in
      Section 5(b).

            "Monthly Redemption" shall mean the redemption of the Debenture
      pursuant to Section 5(a).

            "Monthly Redemption Amount" shall mean, as to a Monthly Redemption,
      1/26th of the aggregate Subscription Amounts paid by all holders of the
      Debentures on the Issuance Date.

            "Monthly Redemption Date" means the 1st of each month, commencing
      immediately following the 11 month anniversary of the Issuance Date and
      continuing until this Debenture is no longer outstanding.

            "Optional Redemption Amount" shall mean the sum of (i) 120% of the
      principal amount of the Debenture then outstanding, (ii) accrued but
      unpaid interest and (iii) all liquidated damages and other amounts due in
      respect of the Debentures.

            "Optional Redemption Date" shall have the meaning set forth in
      Section 5(a).

            "Original Issue Date" shall mean the date of the first issuance of
      any Debenture pursuant to the Purchase Agreement.

            "Person" means a corporation, an association, a partnership,
      organization, a business, an individual, a government or political
      subdivision thereof or a governmental agency.

            "Purchase Agreement" means the Securities Purchase Agreement, dated
      as of the Original Issue Date, to which the Company and the original
      Holder are parties, as amended, modified or supplemented from time to time
      in accordance with its terms.

            "Registration Rights Agreement" means the Registration Rights
      Agreement, dated as of the Original Issue Date, to which the Company and
      the original Holder are parties, as amended, modified or supplemented from
      time to time in accordance with its terms.

            "Securities Act" means the Securities Act of 1933, as amended, and
      the rules and regulations promulgated thereunder.

                                       25
<PAGE>

            "Set Price" shall have the meaning set forth in Section 4(c)(i).

            "Shareholder Approval" means such approval as may be required by the
      applicable rules and regulations of the Principal Market (or any successor
      entity) from the shareholders of the Company with respect to the
      transactions contemplated by the Transaction Documents, including the
      issuance of all of the Underlying Shares and shares of Common Stock
      issuable upon exercise of the Warrants.

            "Trading Day" means (a) a day on which the shares of Common Stock
      are traded on the Principal Market on which the shares of Common Stock are
      then listed or quoted, or (b) if the shares of Common Stock are not quoted
      on a Principal Market, a day on which the shares of Common Stock are
      quoted in the over-the-counter market as reported by the National
      Quotation Bureau Incorporated (or any similar organization or agency
      succeeding its functions of reporting prices); provided, that in the event
      that the shares of Common Stock are not listed or quoted as set forth in
      (a), (b) and (c) hereof, then Trading Day shall mean a Business Day.

            "Transaction Documents" shall have the meaning set forth in the
      Purchase Agreement.

            "Underlying Shares" means the shares of Common Stock issuable upon
      conversion of Debentures or as payment of interest in accordance with the
      terms hereof.

            "Underlying Shares Registration Statement" means a registration
      statement meeting the requirements set forth in the Registration Rights
      Agreement, covering among other things the resale of the Underlying Shares
      and naming the Holder as a "selling stockholder" thereunder.

            "VWAP" means, for any date, the price determined by the first of the
      following clauses that applies: (a) if the Common Stock is then listed or
      quoted on a Principal Market or the OTC Bulletin Board, the daily volume
      weighted average price of the Common Stock for such date (or the nearest
      preceding date) on the Principal Market (or OTC Bulletin Board) on which
      the Common Stock is then listed or quoted as reported by Bloomberg
      Financial L.P. (based on a Trading Day from 9:30 a.m. ET to 4:02 p.m.
      Eastern Time) using the VAP function; (b) if the Common Stock is not then
      listed or quoted on a Principal Market or the OTC Bulletin Board and if
      prices for the Common Stock are then reported in the "pink sheets"
      published by the National Quotation Bureau Incorporated (or a similar
      organization or agency succeeding to its functions of reporting prices),
      the most recent bid price per share of the Common Stock so reported; or
      (c) in all other cases, the fair market value of a share of Common Stock
      as determined by a nationally recognized independent appraiser selected in
      good faith by Purchasers holding a majority of the outstanding principal
      amount of Debentures.

                                       26
<PAGE>

      Section 7. Except as expressly provided herein, no provision of this
Debenture shall alter or impair the obligation of the Company, which is absolute
and unconditional, to pay the principal of, interest and liquidated damages (if
any) on, this Debenture at the time, place, and rate, and in the coin or
currency, herein prescribed. This Debenture is a direct debt obligation of the
Company. This Debenture ranks pari passu with all other Debentures now or
hereafter issued under the terms set forth herein. As long as there are
Debentures outstanding, the Company shall not and shall cause it subsidiaries
not to, without the consent of the Holders, (a) amend its certificate of
incorporation, bylaws or other charter documents so as to adversely affect any
rights of the Holders; (b) repay, repurchase or offer to repay, repurchase or
otherwise acquire shares of its Common Stock or other equity securities other
than as to the Underlying Shares to the extent permitted or required under the
Transaction Documents; or (c) enter into any agreement with respect to any of
the foregoing.

      Section 8. If this Debenture shall be mutilated, lost, stolen or
destroyed, the Company shall execute and deliver, in exchange and substitution
for and upon cancellation of a mutilated Debenture, or in lieu of or in
substitution for a lost, stolen or destroyed Debenture, a new Debenture for the
principal amount of this Debenture so mutilated, lost, stolen or destroyed but
only upon receipt of evidence of such loss, theft or destruction of such
Debenture, and of the ownership hereof, and indemnity, if requested, all
reasonably satisfactory to the Company.

      Section 9. The Company will not and will not permit any of its
subsidiaries to, directly or indirectly, enter into, create, incur, assume or
suffer to exist any indebtedness of any kind, on or with respect to any of its
property or assets now owned or hereafter acquired or any interest therein or
any income or profits therefrom that is senior in any respect to the Company's
obligations under the Debentures.

      Section 10. All questions concerning the construction, validity,
enforcement and interpretation of this Debenture shall be governed by and
construed and enforced in accordance with the internal laws of the State of New
York, without regard to the principles of conflicts of law thereof. Each party
agrees that all legal proceedings concerning the interpretations, enforcement
and defense of the transactions contemplated by any of the Transaction Documents
(whether brought against a party hereto or its respective affiliates, directors,
officers, shareholders, employees or agents) shall be commenced in the state and
federal courts sitting in the City of New York, Borough of Manhattan (the "New
York Courts"). Each party hereto hereby irrevocably submits to the exclusive
jurisdiction of the New York Courts for the adjudication of any dispute
hereunder or in connection herewith or with any transaction contemplated hereby
or discussed herein (including with respect to the enforcement of any of the
Transaction Documents), and hereby irrevocably waives, and agrees not to assert
in any suit, action or proceeding, any claim that it is not personally subject
to the jurisdiction of any such court, or such New York Courts are improper or
inconvenient venue for such proceeding. Each party hereby irrevocably waives
personal service of process and consents to process being served in any such
suit, action or proceeding by mailing a copy thereof via registered

                                       27
<PAGE>

or certified mail or overnight delivery (with evidence of delivery) to such
party at the address in effect for notices to it under this Debenture and agrees
that such service shall constitute good and sufficient service of process and
notice thereof. Nothing contained herein shall be deemed to limit in any way any
right to serve process in any manner permitted by law. Each party hereto hereby
irrevocably waives, to the fullest extent permitted by applicable law, any and
all right to trial by jury in any legal proceeding arising out of or relating to
this Debenture or the transactions contemplated hereby. If either party shall
commence an action or proceeding to enforce any provisions of this Debenture,
then the prevailing party in such action or proceeding shall be reimbursed by
the other party for its attorneys fees and other costs and expenses incurred
with the investigation, preparation and prosecution of such action or
proceeding.

      Section 11. Any waiver by the Company or the Holder of a breach of any
provision of this Debenture shall not operate as or be construed to be a waiver
of any other breach of such provision or of any breach of any other provision of
this Debenture. The failure of the Company or the Holder to insist upon strict
adherence to any term of this Debenture on one or more occasions shall not be
considered a waiver or deprive that party of the right thereafter to insist upon
strict adherence to that term or any other term of this Debenture. Any waiver
must be in writing.

      Section 12. If any provision of this Debenture is invalid, illegal or
unenforceable, the balance of this Debenture shall remain in effect, and if any
provision is inapplicable to any person or circumstance, it shall nevertheless
remain applicable to all other persons and circumstances. If it shall be found
that any interest or other amount deemed interest due hereunder shall violate
applicable laws governing usury, the applicable rate of interest due hereunder
shall automatically be lowered to equal the maximum permitted rate of interest.
The Company covenants (to the extent that it may lawfully do so) that it shall
not at any time insist upon, plead, or in any manner whatsoever claim or take
the benefit or advantage of, any stay, extension or usury law or other law which
would prohibit or forgive the Company from paying all or any portion of the
principal of or interest on the Debentures as contemplated herein, wherever
enacted, now or at any time hereafter in force, or which may affect the
covenants or the performance of this indenture, and the Company (to the extent
it may lawfully do so) hereby expressly waives all benefits or advantage of any
such law, and covenants that it will not, by resort to any such law, hinder,
delay or impeded the execution of any power herein granted to the Holder, but
will suffer and permit the execution of every such as though no such law has
been enacted.

      Section 13. Whenever any payment or other obligation hereunder shall be
due on a day other than a Business Day, such payment shall be made on the next
succeeding Business Day.

                              *********************

                                       28
<PAGE>

      IN WITNESS WHEREOF, the Company has caused this Convertible Debenture to
be duly executed by a duly authorized officer as of the date first above
indicated.

                                    MATRITECH, INC.

                                    By:_____________________________________
                                        Name:
                                        Title:

<PAGE>

                                     ANNEX A

                              NOTICE OF CONVERSION

The undersigned hereby elects to convert principal and, if specified, interest
under the 7.5% Convertible Debenture of Matritech, Inc., (the "Company") due on
_____________ __, 200__, into shares of common stock, $0.01 par value per share
(the "Common Stock"), of the Company according to the conditions hereof, as of
the date written below. If shares are to be issued in the name of a person other
than the undersigned, the undersigned will pay all transfer taxes payable with
respect thereto and is delivering herewith such certificates and opinions as
reasonably requested by the Company in accordance therewith. No fee will be
charged to the holder for any conversion, except for such transfer taxes, if
any.

By the delivery of this Notice of Conversion the undersigned represents and
warrants to the Company that its ownership of the Company's Common Stock does
not exceed the amounts determined in accordance with Section 13(d) of the
Exchange Act, specified under Section 4 of this Debenture.

The undersigned agrees to comply with the prospectus delivery requirements under
the applicable securities laws in connection with any transfer of the aforesaid
shares of Common Stock.

Conversion calculations:

                              Date to Effect Conversion:

                              Principal Amount of Debentures to be Converted

                              Payment of Interest in Common Stock |_| Yes |_| No
                                       If yes, $ _______ of Interest Accrued on
                                       Account of Conversion at Issue

                              Number of shares of Common Stock to be Issued:

                              Applicable Conversion Price:

                              Signature:

                              Name:

                              Address:

<PAGE>

                                   SCHEDULE 1

                               CONVERSION SCHEDULE

7.5% Convertible Debentures due on _____________ __, 200__(6), in the aggregate
principal amount of $____________ issued by Matritech, Inc. This Conversion
Schedule reflects conversions made under Section 4 of the above referenced
Debenture.

                                     Dated:

<TABLE>
<CAPTION>
                                                           Aggregate Principal
                                                             Amount Remaining
                                                              Subsequent to
      Date of Conversion                                        Conversion
     (or for first entry,          Amount of Conversion        (or original               Company Attest
        Issuance Date)                                           Principal
                                                                  Amount)
------------------------------  -------------------------  ---------------------  ------------------------------
<S>                             <C>                        <C>                    <C>

</TABLE>

----------

6   The applicable Closing Date.

                                       31<PAGE>
                                                                     EXHIBIT 4.4

                                                                       EXHIBIT C

NEITHER THIS SECURITY NOR THE SECURITIES INTO WHICH THIS SECURITY IS EXERCISABLE
HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE
SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM
REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "SECURITIES
ACT"), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN
EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR PURSUANT TO AN
AVAILABLE EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION
REQUIREMENTS OF THE SECURITIES ACT AND IN ACCORDANCE WITH APPLICABLE STATE
SECURITIES LAWS AS EVIDENCED BY A LEGAL OPINION OF COUNSEL TO THE TRANSFEROR TO
SUCH EFFECT, THE SUBSTANCE OF WHICH SHALL BE REASONABLY ACCEPTABLE TO THE
COMPANY. THE SECURITIES ISSUABLE UPON EXERCISE OF THIS SECURITY MAY BE PLEDGED
IN CONNECTION WITH A BONA FIDE MARGIN ACCOUNT OR OTHER LOAN SECURED BY SUCH
SECURITIES.

                             STOCK PURCHASE WARRANT

                To Purchase __________ Shares of Common Stock of

                                 MATRITECH, INC.

      THIS STOCK PURCHASE WARRANT CERTIFIES that, for value received,
_____________ (the "Holder"), is entitled, upon the terms and subject to the
limitations on exercise and the conditions hereinafter set forth, at any time on
or after ________(1) __, 200__ (the "Initial Exercise Date") and on or prior to
the close of business on the fifth anniversary of the Initial Exercise Date (the
"Termination Date") but not thereafter, to subscribe for and purchase from
Matritech, Inc., a corporation incorporated in the State of Delaware (the
"Company"), up to ____________ shares (the "Warrant Shares") of Common Stock,
par value $0.01 per share, of the Company (the "Common Stock"). The purchase
price of one share of Common Stock (the "Exercise Price") under this Warrant
shall be $____(2), subject to adjustment hereunder. The Exercise Price and the
number of Warrant Shares for which the Warrant is exercisable shall be subject
to adjustment as provided herein. CAPITALIZED TERMS USED AND NOT OTHERWISE
DEFINED HEREIN SHALL HAVE THE MEANINGS SET FORTH IN THAT CERTAIN SECURITIES
PURCHASE AGREEMENT (THE "PURCHASE AGREEMENT"), DATED MARCH 31, 2003, BETWEEN THE
COMPANY AND THE INVESTORS SIGNATORY THERETO.

----------
1   The applicable Closing Date.

2   The Closing Price on the applicable Closing Date.

                                       1
<PAGE>

      1. Title to Warrant. Prior to the Termination Date and subject to
compliance with applicable laws and Section 7 of this Warrant, this Warrant and
all rights hereunder are transferable, in whole or in part, at the office or
agency of the Company by the Holder in person or by duly authorized attorney,
upon surrender of this Warrant together with the Assignment Form annexed hereto
properly endorsed; provided, however, during any 12 month period and except for
transfers to an Affiliate of the Holder, the Holder, collectively with successor
Holders, may not transfer this Warrant in more than two transactions to more
than four assignees per transaction. The transferee shall sign an investment
letter in form and substance reasonably satisfactory to the Company.

      2. Authorization of Shares. The Company covenants that all Warrant Shares
which may be issued upon the exercise of the purchase rights represented by this
Warrant will, upon exercise of the purchase rights represented by this Warrant
and in accordance with the terms hereof, be duly authorized, validly issued,
fully paid and nonassessable and free from all taxes, liens and charges in
respect of the issue thereof imposed by the Company other than restrictions on
transfer provided for in the Transaction Documents.

      3. Exercise of Warrant.

            (a) Except as provided in Section 4 herein, exercise of the purchase
      rights represented by this Warrant may be made at any time or times on or
      after the Initial Exercise Date and on or before the Termination Date by
      the surrender of this Warrant and the Notice of Exercise Form annexed
      hereto duly executed, at the office of the Company (or such other office
      or agency of the Company as it may designate by notice in writing to the
      registered Holder at the address of such Holder appearing on the books of
      the Company) and upon payment of the Exercise Price of the shares thereby
      purchased by wire transfer or cashier's check drawn on a United States
      bank or by means of a cashless exercise pursuant to Section 3(d), the
      Holder shall be entitled to receive a certificate for the number of
      Warrant Shares so purchased. Certificates for shares purchased hereunder
      shall be delivered to the Holder within five (5) Trading Days after the
      date on which this Warrant shall have been exercised as aforesaid. This
      Warrant shall be deemed to have been exercised and such certificate or
      certificates shall be deemed to have been issued, and Holder or any other
      person so designated to be named therein shall be deemed to have become a
      holder of record of such shares for all purposes, as of the date the
      Warrant has been exercised by payment to the Company of the Exercise Price
      and all taxes required to be paid by the Holder, if any, pursuant to
      Section 5 prior to the issuance of such shares, have been paid. If the
      Company fails to deliver to the Holder a certificate or certificates
      representing the Warrant Shares pursuant to this Section 3(a) by the fifth
      Trading Day after the date of exercise, then the Holder will have the
      right to rescind such exercise. In addition to any other rights available
      to the Holder, if the Company fails to deliver to the Holder a certificate
      or certificates representing the Warrant Shares pursuant to an exercise by
      the fifth Trading Day after the date of exercise and the Holder has not
      rescinded such exercise pursuant to this Section 3(a), and if after such
      fifth Trading Day the Holder is required by its broker to purchase (in an
      open market transaction or otherwise) shares of Common Stock to deliver in
      satisfaction of a sale by the Holder of

                                       2
<PAGE>

      the Warrant Shares which the Holder anticipated receiving upon such
      exercise (a "Buy-In"), then the Company shall (1) pay in cash to the
      Holder the amount by which (x) the Holder's total purchase price
      (including brokerage commissions, if any) for the shares of Common Stock
      so purchased exceeds (y) the amount obtained by multiplying (A) the number
      of Warrant Shares that the Company was required to deliver to the Holder
      in connection with the exercise at issue times (B) the price at which the
      sell order giving rise to such purchase obligation was executed, and (2)
      at the option of the Holder, either reinstate the portion of the Warrant
      and equivalent number of Warrant Shares for which such exercise was not
      honored or deliver to the Holder the number of shares of Common Stock that
      would have been issued had the Company timely complied with its exercise
      and delivery obligations hereunder. For example, if the Holder purchases
      Common Stock having a total purchase price of $11,000 to cover a Buy-In
      with respect to an attempted exercise of shares of Common Stock with an
      aggregate sale price giving rise to such purchase obligation of $10,000,
      under clause (1) of the immediately preceding sentence the Company shall
      be required to pay the Holder $1,000. The Holder shall provide the Company
      written notice indicating the amounts payable to the Holder in respect of
      the Buy-In, together with applicable confirmations and other evidence
      reasonably requested by the Company. Nothing herein shall limit a Holder's
      right to pursue any other remedies available to it hereunder, at law or in
      equity including, without limitation, a decree of specific performance
      and/or injunctive relief with respect to the Company's failure to timely
      deliver certificates representing shares of Common Stock upon exercise of
      the Warrant as required pursuant to the terms hereof.

            (b) If this Warrant shall have been exercised in part, the Company
      shall, at the time of delivery of the certificate or certificates
      representing Warrant Shares, deliver to Holder a new Warrant evidencing
      the rights of Holder to purchase the unpurchased Warrant Shares called for
      by this Warrant, which new Warrant shall in all other respects be
      identical with this Warrant.

            (c) Notwithstanding anything herein to the contrary, in no event
      shall the Holder be permitted to exercise this Warrant for Warrant Shares
      to the extent that (i) the number of shares of Common Stock beneficially
      owned by such Holder, together with any affiliate thereof (other than
      Warrant Shares issuable upon exercise of this Warrant) plus (ii) the
      number of Warrant Shares issuable upon exercise of this Warrant, would be
      equal to or exceed 4.9999% of the number of shares of Common Stock then
      issued and outstanding, including shares issuable upon exercise of this
      Warrant held by such Holder after application of this Section 3(c). As
      used herein, beneficial ownership shall be determined in accordance with
      Section 13(d) of the Exchange Act and the rules promulgated thereunder. To
      the extent that the limitation contained in this Section 3(c) applies, the
      determination of whether this Warrant is exercisable (in relation to other
      securities owned by the Holder) and of which a portion of this Warrant is
      exercisable shall be in the sole discretion of such Holder, and the
      submission of a Notice of Exercise shall be deemed to be such Holder's
      determination of whether this Warrant is exercisable (in relation to other
      securities owned by such Holder) and of which portion of this Warrant is
      exercisable, in each case subject to such aggregate percentage limitation,
      and the Company shall have no obligation to verify or confirm the accuracy
      of such determination. Nothing contained herein shall be deemed to
      restrict the right of a Holder

                                       3
<PAGE>

      to exercise this Warrant into Warrant Shares at such time as such exercise
      will not violate the provisions of this Section 3(c). The provisions of
      this Section 3(c) may be waived by the Holder upon, at the election of the
      Holder, not less than 61 days' prior notice to the Company, and the
      provisions of this Section 3(c) shall continue to apply until such 61st
      day (or such later date, as determined by the Holder, as may be specified
      in such notice of waiver). No exercise of this Warrant in violation of
      this Section 3(c) but otherwise in accordance with this Warrant shall
      affect the status of the Warrant Shares as validly issued, fully-paid and
      nonassessable.

            (d) If at any time after one year from the date of issuance of this
      Warrant there is no effective Registration Statement registering the
      resale of the Warrant Shares by the Holder, this Warrant may also be
      exercised at such time by means of a "cashless exercise" in which the
      Holder shall be entitled to receive a certificate for the number of
      Warrant Shares equal to the quotient obtained by dividing [(A-B) (X)] by
      (A), where:

            (A) = the Closing Bid Price on the Trading Day preceding
                  the date of such election;

            (B) = the Exercise Price of the Warrants, as adjusted; and

            (X) = the number of Warrant Shares issuable upon exercise
                  of the Warrants in accordance with the terms of this
                  Warrant.

      4. No Fractional Shares or Scrip. No fractional shares or scrip
representing fractional shares shall be issued upon the exercise of this
Warrant. As to any fraction of a share which Holder would otherwise be entitled
to purchase upon such exercise, the Company shall pay a cash adjustment in
respect of such final fraction in an amount equal to such fraction multiplied by
the Exercise Price.

      5. Charges, Taxes and Expenses. Issuance of certificates for Warrant
Shares shall be made without charge to the Holder for any issue or transfer tax
or other incidental expense in respect of the issuance of such certificate, all
of which taxes and expenses shall be paid by the Company, and such certificates
shall be issued in the name of the Holder or in such name or names as may be
directed by the Holder; provided, however, that in the event certificates for
Warrant Shares are to be issued in a name other than the name of the Holder,
this Warrant when surrendered for exercise shall be accompanied by the
Assignment Form attached hereto duly executed by the Holder; and the Company may
require, as a condition thereto, the payment of a sum sufficient to reimburse it
for any transfer tax incidental thereto.

      6. Closing of Books. The Company will not close its stockholder books or
records in any manner which prevents the timely exercise of this Warrant,
pursuant to the terms hereof.

      7. Transfer, Division and Combination.

            (a) Subject to compliance with any applicable securities laws and
      the conditions set forth in Sections 1 and 7(f) hereof and to the
      provisions of Section 4.1 of

                                       4
<PAGE>

      the Purchase Agreement, this Warrant and all rights hereunder are
      transferable, in whole or in part, upon surrender of this Warrant at the
      principal office of the Company, together with a written assignment of
      this Warrant substantially in the form attached hereto duly executed by
      the Holder or its agent or attorney and funds sufficient to pay any
      transfer taxes payable upon the making of such transfer. Upon such
      surrender and, if required, such payment, the Company shall execute and
      deliver a new Warrant or Warrants in the name of the assignee or assignees
      and in the denomination or denominations specified in such instrument of
      assignment, and shall issue to the assignor a new Warrant evidencing the
      portion of this Warrant not so assigned, and this Warrant shall promptly
      be cancelled. A Warrant, if properly assigned, may be exercised by a new
      holder for the purchase of Warrant Shares without having a new Warrant
      issued.

            (b) This Warrant may be divided or combined with other Warrants upon
      presentation hereof at the aforesaid office of the Company, together with
      a written notice specifying the names and denominations in which new
      Warrants are to be issued, signed by the Holder or its agent or attorney.
      Subject to compliance with Section 7(a), as to any transfer which may be
      involved in such division or combination, the Company shall execute and
      deliver a new Warrant or Warrants in exchange for the Warrant or Warrants
      to be divided or combined in accordance with such notice.

            (c) The Company shall prepare, issue and deliver at its own expense
      (other than transfer taxes) the new Warrant or Warrants under this Section
      7.

            (d) The Company agrees to maintain, at its aforesaid office, books
      for the registration and the registration of transfer of the Warrants.

            (e) If, at the time of the surrender of this Warrant in connection
      with any transfer of this Warrant, the transfer of this Warrant shall not
      be registered pursuant to an effective registration statement under the
      Securities Act and under applicable state securities or blue sky laws, the
      Company may require, as a condition of allowing such transfer (i) that the
      Holder or transferee of this Warrant, as the case may be, furnish to the
      Company a written opinion of counsel (which opinion shall be in form,
      substance and scope customary for opinions of counsel in comparable
      transactions) to the effect that such transfer may be made without
      registration under the Securities Act and under applicable state
      securities or blue sky laws, (ii) that the holder or transferee execute
      and deliver to the Company an investment letter in form and substance
      acceptable to the Company and (iii) that the transferee be an "accredited
      investor" as defined in Rule 501(a)(1), (a)(2), (a)(3), (a)(7), or (a)(8)
      promulgated under the Securities Act or a qualified institutional buyer as
      defined in Rule 144A(a) under the Securities Act.

      8. No Rights as Shareholder until Exercise. This Warrant does not entitle
the Holder to any voting rights or other rights as a shareholder of the Company
prior to the exercise hereof. Upon the surrender of this Warrant and the payment
of the aggregate Exercise Price (or by means of a cashless exercise), the
Warrant Shares so purchased shall be and be deemed to be issued to such Holder
as the record owner of such shares as of the close of business on the later of
the date of such surrender or payment.

                                       5
<PAGE>

      9. Loss, Theft, Destruction or Mutilation of Warrant. The Company
covenants that upon receipt by the Company of evidence reasonably satisfactory
to it of the loss, theft, destruction or mutilation of this Warrant or any stock
certificate relating to the Warrant Shares, and in case of loss, theft or
destruction, of indemnity or security reasonably satisfactory to it (which, in
the case of the Warrant, shall not include the posting of any bond), and upon
surrender and cancellation of such Warrant or stock certificate, if mutilated,
the Company will make and deliver a new Warrant or stock certificate of like
tenor and dated as of such cancellation, in lieu of such Warrant or stock
certificate.

      10. Saturdays, Sundays, Holidays, etc. If the last or appointed day for
the taking of any action or the expiration of any right required or granted
herein shall be a Saturday, Sunday or a legal holiday, then such action may be
taken or such right may be exercised on the next succeeding day not a Saturday,
Sunday or legal holiday.

      11. Adjustments of Exercise Price and Number of Warrant Shares.

            (a) Stock Splits, etc. The number and kind of securities purchasable
      upon the exercise of this Warrant and the Exercise Price shall be subject
      to adjustment from time to time upon the happening of any of the
      following. In case the Company shall (i) pay a dividend in shares of
      Common Stock or make a distribution in shares of Common Stock to holders
      of its outstanding Common Stock, (ii) subdivide its outstanding shares of
      Common Stock into a greater number of shares, (iii) combine its
      outstanding shares of Common Stock into a smaller number of shares of
      Common Stock, or (iv) issue any shares of its capital stock in a
      reclassification of the Common Stock, then the number of Warrant Shares
      purchasable upon exercise of this Warrant immediately prior thereto shall
      be adjusted so that the Holder shall be entitled to receive the kind and
      number of Warrant Shares or other securities of the Company which it would
      have owned or have been entitled to receive had such Warrant been
      exercised in advance thereof. Upon each such adjustment of the kind and
      number of Warrant Shares or other securities of the Company which are
      purchasable hereunder, the Holder shall thereafter be entitled to purchase
      the number of Warrant Shares or other securities resulting from such
      adjustment at an Exercise Price per Warrant Share or other security
      obtained by multiplying the Exercise Price in effect immediately prior to
      such adjustment by the number of Warrant Shares purchasable pursuant
      hereto immediately prior to such adjustment and dividing by the number of
      Warrant Shares or other securities of the Company resulting from such
      adjustment. An adjustment made pursuant to this paragraph shall become
      effective immediately after the effective date of such event retroactive
      to the record date, if any, for such event.

            (b) Anti-Dilution Provisions. During the Exercise Period, the
      Exercise Price for which this Warrant is then exercisable shall be subject
      to adjustment from time to time as provided in this Section 11(b). In the
      event that any adjustment of the Exercise Price as required herein results
      in a fraction of a cent, such Exercise Price shall be rounded up or down
      to the nearest cent.

                  (i) Adjustment of Exercise Price. Except as set forth in
            Section 11(b)(ii)(E), if and whenever the Company issues or sells,
            or in accordance with Section 11(b) hereof is deemed to have issued
            or sold, any shares of Common

                                       6
<PAGE>

            Stock for a consideration per share of less than the Exercise Price
            in effect immediately prior to such sale or issuance or for no
            consideration (such lower price, the "Base Share Price" and such
            issuances collectively, a "Dilutive Issuance"), then, (A) if such
            Dilutive Issuance occurred prior to the date the Holder no longer
            holds any Debentures ("Dilution Trigger Date"), the Exercise Price
            shall be reduced to equal the Base Share Price, and (B) if such
            Dilutive Issuance occurred after the Dilution Trigger Date, the
            Exercise Price shall be multiplied by a fraction of which the
            numerator shall be the number of shares of Common Stock Outstanding
            immediately prior to the Dilutive Issuance plus the number of shares
            of Common Stock which the aggregate offering price for such Dilutive
            Issuance (assuming receipt by the Corporation in full of all
            consideration payable upon exercise of such rights, options or
            warrants) would purchase at the Exercise Price, and the denominator
            of which shall be the sum of the number of shares of Common Stock
            Outstanding immediately prior to the Dilutive Issuance plus the
            number of shares of Common Stock so issued or issuable in connection
            with the Dilutive Issuance. Such adjustment shall be made whenever
            such shares of Common Stock or Capital Share Equivalents are issued.
            For purposes of this Section 11(b), "Common Stock outstanding" as of
            a given date shall be the number of shares of Common Stock
            (excluding treasury shares, if any) outstanding plus the number of
            shares of Common Stock issuable upon exercise, conversion and/or
            exchange of any outstanding Common Stock Equivalents.

                  (ii) Effect on Exercise Price of Certain Events. For purposes
            of determining the adjusted Exercise Price under Section 11(b)
            hereof, the following will be applicable:

                        (A) Issuance of Rights or Options. If the Company in any
                  manner issues or grants any warrants, rights or options,
                  whether or not immediately exercisable, to subscribe for or to
                  purchase Common Stock or other securities exercisable,
                  convertible into or exchangeable for Common Stock
                  ("Convertible Securities") (such warrants, rights and options
                  to purchase Common Stock or Convertible Securities are
                  hereinafter referred to as "Options") and the effective price
                  per share for which Common Stock is issuable upon the exercise
                  of such Options is less than the Exercise Price ("Below Base
                  Price Options"), then the maximum total number of shares of
                  Common Stock issuable upon the exercise of all such Below Base
                  Price Options (assuming full exercise, conversion or exchange
                  of Convertible Securities, if applicable) will, as of the date
                  of the issuance or grant of such Below Base Price Options, be
                  deemed to be outstanding and to have been issued and sold by
                  the Company for such price per share and the maximum
                  consideration payable to the Company upon such exercise
                  (assuming full exercise, conversion or exchange of Convertible
                  Securities, if applicable) will be deemed to have been
                  received by the Company. For purposes of the preceding
                  sentence, the "effective price per share for which Common
                  Stock is issuable upon the exercise of such Below Base Price
                  Options" is determined by dividing (i)

                                       7
<PAGE>

                  the total amount, if any, received or receivable by the
                  Company as consideration for the issuance or granting of all
                  such Below Base Price Options, plus the minimum aggregate
                  amount of additional consideration, if any, payable to the
                  Company upon the exercise of all such Below Base Price
                  Options, plus, in the case of Convertible Securities issuable
                  upon the exercise of such Below Base Price Options, the
                  minimum aggregate amount of additional consideration payable
                  upon the exercise, conversion or exchange thereof at the time
                  such Convertible Securities first become exercisable,
                  convertible or exchangeable, by (ii) the maximum total number
                  of shares of Common Stock issuable upon the exercise of all
                  such Below Base Price Options (assuming full conversion of
                  Convertible Securities, if applicable). No further adjustment
                  to the Exercise Price will be made upon the actual issuance of
                  such Common Stock upon the exercise of such Below Base Price
                  Options or upon the exercise, conversion or exchange of
                  Convertible Securities issuable upon exercise of such Below
                  Base Price Options.

                        (B) Issuance of Convertible Securities. If the Company
                  in any manner issues or sells any Convertible Securities,
                  whether or not immediately convertible (other than where the
                  same are issuable upon the exercise of Options) and the
                  effective price per share for which Common Stock is issuable
                  upon such exercise, conversion or exchange is less than the
                  Exercise Price, then the maximum total number of shares of
                  Common Stock issuable upon the exercise, conversion or
                  exchange of all such Convertible Securities will, as of the
                  date of the issuance of such Convertible Securities, be deemed
                  to be outstanding and to have been issued and sold by the
                  Company for such price per share and the maximum consideration
                  payable to the Company upon such exercise (assuming full
                  exercise, conversion or exchange of Convertible Securities, if
                  applicable) will be deemed to have been received by the
                  Company. For the purposes of the preceding sentence, the
                  "effective price per share for which Common Stock is issuable
                  upon such exercise, conversion or exchange" is determined by
                  dividing (i) the total amount, if any, received or receivable
                  by the Company as consideration for the issuance or sale of
                  all such Convertible Securities, plus the minimum aggregate
                  amount of additional consideration, if any, payable to the
                  Company upon the exercise, conversion or exchange thereof at
                  the time such Convertible Securities first become exercisable,
                  convertible or exchangeable, by (ii) the maximum total number
                  of shares of Common Stock issuable upon the exercise,
                  conversion or exchange of all such Convertible Securities. No
                  further adjustment to the Exercise Price will be made upon the
                  actual issuance of such Common Stock upon exercise, conversion
                  or exchange of such Convertible Securities.

                        (C) Change in Option Price or Conversion Rate. If there
                  is a change at any time in (i) the amount of additional
                  consideration

                                       8
<PAGE>

                  payable to the Company upon the exercise of any Options; (ii)
                  the amount of additional consideration, if any, payable to the
                  Company upon the exercise, conversion or exchange of any
                  Convertible Securities; or (iii) the rate at which any
                  Convertible Securities are convertible into or exchangeable
                  for Common Stock (in each such case, other than under or by
                  reason of provisions designed to protect against dilution),
                  the Exercise Price in effect at the time of such change will
                  be readjusted to the Exercise Price which would have been in
                  effect at such time had such Options or Convertible Securities
                  still outstanding provided for such changed additional
                  consideration or changed conversion rate, as the case may be,
                  at the time initially granted, issued or sold.

                        (D) Calculation of Consideration Received. If any Common
                  Stock, Options or Convertible Securities are issued, granted
                  or sold for cash, the consideration received therefor for
                  purposes of this Warrant will be the amount received by the
                  Company therefor, before deduction of reasonable commissions,
                  underwriting discounts or allowances or other reasonable
                  expenses paid or incurred by the Company in connection with
                  such issuance, grant or sale. In case any Common Stock,
                  Options or Convertible Securities are issued or sold for a
                  consideration part or all of which shall be other than cash,
                  the amount of the consideration other than cash received by
                  the Company will be the fair market value of such
                  consideration, except where such consideration consists of
                  securities, in which case the amount of consideration received
                  by the Company will be the fair market value (closing bid
                  price, if traded on any market) thereof as of the date of
                  receipt. In case any Common Stock, Options or Convertible
                  Securities are issued in connection with any merger or
                  consolidation in which the Company is the surviving
                  corporation, the amount of consideration therefor will be
                  deemed to be the fair market value of such portion of the net
                  assets and business of the non-surviving corporation as is
                  attributable to such Common Stock, Options or Convertible
                  Securities, as the case may be. The fair market value of any
                  consideration other than cash or securities will be determined
                  in good faith by an investment banker or other appropriate
                  expert of national reputation selected by the Company and
                  reasonably acceptable to the holder hereof, with the costs of
                  such appraisal to be borne by the Company.

                        (E) Exceptions to Adjustment of Exercise Price.
                  Notwithstanding the foregoing, no adjustment will be made
                  under this Section 11(b) in respect of the issuance of (1)
                  shares of Common Stock or options to employees, consultants,
                  advisors, officers or directors of the Company pursuant to any
                  stock or option plan duly adopted by a majority of the
                  non-employee members of the Board of Directors of the Company
                  or a majority of the members of a committee of non-employee
                  directors established for such purpose, (2) securities upon
                  the exercise of, or in connection with the payment of interest
                  on or redemption of, the

                                       9
<PAGE>

                  Debentures or any Debentures of this series or of any other
                  series or security issued by the Company in connection with
                  the offer and sale of this Company's securities pursuant to
                  the Purchase Agreement, or (3) securities upon the exercise of
                  or conversion of any convertible securities, options or
                  warrants issued and outstanding on the Original Issue Date,
                  provided that the securities have not been amended since the
                  date of the Purchase Agreement, (4) securities in connection
                  with acquisitions or strategic investments (including, without
                  limitation, any licensing or distribution arrangements), the
                  primary purpose of which is not to raise capital, or (5)
                  securities to financial institutions or lessors in connection
                  with commercial credit arrangements, equipment financings or
                  similar transactions, where the principal consideration for
                  such transaction is not the issuance of such securities.

                  (iii) Minimum Adjustment of Exercise Price. No adjustment of
            the Exercise Price shall be made in an amount of less than 1% of the
            Exercise Price in effect at the time such adjustment is otherwise
            required to be made, but any such lesser adjustment shall be carried
            forward and shall be made at the time and together with the next
            subsequent adjustment which, together with any adjustments so
            carried forward, shall amount to not less than 1% of such Exercise
            Price.

                  (iv) Expiration of Convertible Securities and Options. If, in
            any case, the total number of shares of Common Stock issuable upon
            exercise of any Option or upon exercise, conversion or exchange of
            any Convertible Security is not, in fact, issued and the rights to
            exercise such Option or to exercise, convert or exchange such
            Convertible Security shall have expired or terminated, the Exercise
            Price then in effect will be readjusted to the Exercise Price which
            would have been in effect at the time of such expiration or
            termination had such Option or Convertible Securities, to the extent
            outstanding immediately prior to such expiration or termination
            (other than in respect of the actual number of shares of Common
            Stock issued upon exercise or conversion thereof), never been
            issued; provided, however, prior to such adjustment, the Company
            shall have notified the Holder at least 5 Trading Days prior to the
            date such adjustment occurs.

      12. Reorganization, Reclassification, Merger, Consolidation or Disposition
of Assets. In case the Company shall reorganize its capital, reclassify its
capital stock, consolidate or merge with or into another corporation (where the
Company is not the surviving corporation or where there is a change in or
distribution with respect to the Common Stock of the Company), or sell, transfer
or otherwise dispose of all or substantially all its property, assets or
business to another corporation and, pursuant to the terms of such
reorganization, reclassification, merger, consolidation or disposition of
assets, shares of common stock of the successor or acquiring corporation, or any
cash, shares of stock or other securities or property of any nature whatsoever
(including warrants or other subscription or purchase rights) in addition to or
in lieu of common stock of the successor or acquiring corporation ("Other
Property"), are to be received by or distributed to the holders of Common Stock
of the Company, then the Holder shall have the right

                                       10
<PAGE>

thereafter to receive upon exercise of this Warrant, the number of shares of
Common Stock of the successor or acquiring corporation or of the Company, if it
is the surviving corporation, and Other Property receivable upon or as a result
of such reorganization, reclassification, merger, consolidation or disposition
of assets by a Holder of the number of shares of Common Stock for which this
Warrant is exercisable immediately prior to such event. In case of any such
reorganization, reclassification, merger, consolidation or disposition of
assets, the successor or acquiring corporation (if other than the Company) shall
expressly assume the due and punctual observance and performance of each and
every covenant and condition of this Warrant to be performed and observed by the
Company and all the obligations and liabilities hereunder, subject to such
modifications as may be deemed appropriate (as determined in good faith by
resolution of the Board of Directors of the Company) in order to provide for
adjustments of Warrant Shares for which this Warrant is exercisable which shall
be as nearly equivalent as practicable to the adjustments provided for in this
Section 12. For purposes of this Section 12, "common stock of the successor or
acquiring corporation" shall include stock of such corporation of any class
which is not preferred as to dividends or assets over any other class of stock
of such corporation and which is not subject to redemption and shall also
include any evidences of indebtedness, shares of stock or other securities which
are convertible into or exchangeable for any such stock, either immediately or
upon the arrival of a specified date or the happening of a specified event and
any warrants or other rights to subscribe for or purchase any such stock. The
foregoing provisions of this Section 12 shall similarly apply to successive
reorganizations, reclassifications, mergers, consolidations or disposition of
assets.

      13. Voluntary Adjustment by the Company. The Company may at any time
during the term of this Warrant reduce the then current Exercise Price to any
amount and for any period of time deemed appropriate by the Board of Directors
of the Company.

      14. Notice of Adjustment. Whenever the number of Warrant Shares or number
or kind of securities or other property purchasable upon the exercise of this
Warrant or the Exercise Price is adjusted, as herein provided, the Company shall
give notice thereof to the Holder, which notice shall state the number of
Warrant Shares (and other securities or property) purchasable upon the exercise
of this Warrant and the Exercise Price of such Warrant Shares (and other
securities or property) after such adjustment, setting forth a brief statement
of the facts requiring such adjustment and setting forth the computation by
which such adjustment was made.

      15. Notice of Corporate Action. If at any time:

            (a) the Company shall take a record of the holders of its Common
      Stock for the purpose of entitling them to receive a dividend or other
      distribution, or any right to subscribe for or purchase any evidences of
      its indebtedness, any shares of stock of any class or any other securities
      or property, or to receive any other right, or

            (b) there shall be any capital reorganization of the Company, any
      reclassification or recapitalization of the capital stock of the Company
      or any consolidation or merger of the Company with, or any sale, transfer
      or other disposition of all or substantially all the property, assets or
      business of the Company to, another corporation or,

                                       11
<PAGE>

            (c) there shall be a voluntary or involuntary dissolution,
      liquidation or winding up of the Company;

then, in any one or more of such cases, the Company shall give to Holder (i) at
least 10 days' prior written notice of the date on which a record date shall be
selected for such dividend, distribution or right or for determining rights to
vote in respect of any such reorganization, reclassification, merger,
consolidation, sale, transfer, disposition, liquidation or winding up, and (ii)
in the case of any such reorganization, reclassification, merger, consolidation,
sale, transfer, disposition, dissolution, liquidation or winding up, at least 10
days' prior written notice of the date when the same shall take place. Such
notice in accordance with the foregoing clause also shall specify (i) the date
on which any such record is to be taken for the purpose of such dividend,
distribution or right, the date on which the holders of Common Stock shall be
entitled to any such dividend, distribution or right, and the amount and
character thereof, and (ii) the date on which any such reorganization,
reclassification, merger, consolidation, sale, transfer, disposition,
dissolution, liquidation or winding up is to take place and the time, if any
such time is to be fixed, as of which the holders of Common Stock shall be
entitled to exchange their Warrant Shares for securities or other property
deliverable upon such disposition, dissolution, liquidation or winding up. Each
such written notice shall be sufficiently given if addressed to Holder at the
last address of Holder appearing on the books of the Company and delivered in
accordance with Section 17(d).

      16. Authorized Shares. The Company covenants that during the period the
Warrant is outstanding, it will reserve from its authorized and unissued Common
Stock a sufficient number of shares to provide for the issuance of the Warrant
Shares upon the exercise of any purchase rights under this Warrant. The Company
further covenants that its issuance of this Warrant shall constitute full
authority to its officers who are charged with the duty of executing stock
certificates to execute and issue the necessary certificates for the Warrant
Shares upon the exercise of the purchase rights under this Warrant. The Company
will take all such reasonable action as may be necessary to assure that such
Warrant Shares may be issued as provided herein without violation of any
applicable law or regulation, or of any requirements of the Principal Market
upon which the Common Stock may be listed.

      Except and to the extent as waived or consented to by the Holder, the
Company shall not by any action, including, without limitation, amending its
certificate of incorporation or through any reorganization, transfer of assets,
consolidation, merger, dissolution, issue or sale of securities or any other
voluntary action, avoid or seek to avoid the observance or performance of any of
the terms of this Warrant, but will at all times in good faith assist in the
carrying out of all such terms and in the taking of all such actions as may be
necessary or appropriate to protect the rights of Holder as set forth in this
Warrant against impairment. Without limiting the generality of the foregoing,
the Company will (a) not increase the par value of any Warrant Shares above the
amount payable therefor upon such exercise immediately prior to such increase in
par value, (b) take all such action as may be necessary or appropriate in order
that the Company may validly and legally issue fully paid and nonassessable
Warrant Shares upon the exercise of this Warrant, and (c) use commercially
reasonable efforts to obtain all such authorizations, exemptions or consents
from any public regulatory body having jurisdiction thereof as may be necessary
to enable the Company to perform its obligations under this Warrant.

                                       12
<PAGE>

      17. Miscellaneous.

            (a) Jurisdiction. This Warrant shall constitute a contract under the
laws of New York, without regard to its conflict of law, principles or rules.

            (b) Restrictions. The Holder acknowledges that the Warrant Shares
acquired upon the exercise of this Warrant, if not registered, will have
restrictions upon resale imposed by state and federal securities laws.

            (c) Nonwaiver and Expenses. No course of dealing or any delay or
failure to exercise any right hereunder on the part of Holder shall operate as a
waiver of such right or otherwise prejudice Holder's rights, powers or remedies,
notwithstanding all rights hereunder terminate on the Termination Date. If the
Company willfully and knowingly fails to comply with any provision of this
Warrant, which results in any material damages to the Holder, the Company shall
pay to Holder such amounts as shall be sufficient to cover any costs and
expenses including, but not limited to, reasonable attorneys' fees, including
those of appellate proceedings, incurred by Holder in collecting any amounts due
pursuant hereto or in otherwise enforcing any of its rights, powers or remedies
hereunder.

            (d) Notices. Any notice, request or other document required or
permitted to be given or delivered to the Holder by the Company shall be
delivered in accordance with the notice provisions of the Purchase Agreement.

            (e) Limitation of Liability. No provision hereof, in the absence of
any affirmative action by Holder to exercise this Warrant or purchase Warrant
Shares, and no enumeration herein of the rights or privileges of Holder, shall
give rise to any liability of Holder for the purchase price of any Common Stock
or as a stockholder of the Company, whether such liability is asserted by the
Company or by creditors of the Company.

            (f) Remedies. Holder, in addition to being entitled to exercise all
rights granted by law, including recovery of damages, will be entitled to
specific performance of its rights under this Warrant. The Company agrees that
monetary damages would not be adequate compensation for any loss incurred by
reason of a breach by it of the provisions of this Warrant and hereby agrees to
waive the defense in any action for specific performance that a remedy at law
would be adequate.

            (g) Successors and Assigns. Subject to applicable securities laws,
this Warrant and the rights and obligations evidenced hereby shall inure to the
benefit of and be binding upon the successors of the Company and the successors
and permitted assigns of Holder. The provisions of this Warrant are intended to
be for the benefit of all Holders from time to time of this Warrant and shall be
enforceable by any such Holder or holder of Warrant Shares.

            (h) Amendment. This Warrant may be modified or amended or the
provisions hereof waived with the written consent of the Company and the Holder.

                                       13
<PAGE>

            (i) Severability. Wherever possible, each provision of this Warrant
shall be interpreted in such manner as to be effective and valid under
applicable law, but if any provision of this Warrant shall be prohibited by or
invalid under applicable law, such provision shall be ineffective to the extent
of such prohibition or invalidity, without invalidating the remainder of such
provisions or the remaining provisions of this Warrant.

            (j) Headings. The headings used in this Warrant are for the
convenience of reference only and shall not, for any purpose, be deemed a part
of this Warrant.

                              ********************

                                       14
<PAGE>

      IN WITNESS WHEREOF, the Company has caused this Warrant to be executed by
its officer thereunto duly authorized.

Dated:  ________ __, 200__

                                            MATRITECH, INC.

                                            By:_________________________________
                                                  Name:
                                                  Title:

                                       15
<PAGE>

                               NOTICE OF EXERCISE

To: Matritech, Inc.

      (1)______The undersigned hereby elects to purchase ________ Warrant Shares
of Matritech, Inc. pursuant to the terms of the attached Warrant (only if
exercised in full), and tenders herewith payment of the exercise price in full,
together with all applicable transfer taxes, if any.

      (2)______Payment shall take the form of (check applicable box):

            |_| in lawful money of the United States; or

            |_| the cancellation of such number of Warrant Shares as is
            necessary, in accordance with the formula set forth in subsection
            3(d), to exercise this Warrant with respect to the maximum number of
            Warrant Shares purchasable pursuant to the cashless exercise
            procedure set forth in subsection 3(d).

      (3)______Please issue a certificate or certificates representing said
Warrant Shares in the name of the undersigned or in such other name as is
specified below:

            ___________________________________

The Warrant Shares shall be delivered to the following:

            ___________________________________

            ___________________________________

            ___________________________________

      _________ (4) Accredited Investor/Qualified Institutional Buyer. The
undersigned is either: (i) an "accredited investor" as defined in Rule
501(a)(1), (a)(2), (a)(3), (a)(7) or (a)(8) under the Securities Act of 1933, as
amended (the "Securities Act") or (ii) a qualified institutional buyer as
defined in Rule 144(A)(a) under the Securities Act.

                                            [PURCHASER]

                                            By: ______________________________
                                                  Name:
                                                  Title:

                                            Dated:  __________________________

<PAGE>

                                 ASSIGNMENT FORM

                    (To assign the foregoing warrant, execute
                   this form and supply required information.
                 Do not use this form to exercise the warrant.)

      FOR VALUE RECEIVED, the foregoing Warrant and all rights evidenced thereby
are hereby assigned to

_______________________________________________ whose address is

_______________________________________________________________.

_______________________________________________________________

                                                 Dated:  ______________, _______

                           Holder's Signature:_____________________________

                           Holder's Address:_______________________________

                                            _______________________________

Signature Guaranteed: ___________________________________________

NOTE: The signature to this Assignment Form must correspond with the name as it
appears on the face of the Warrant, without alteration or enlargement or any
change whatsoever, and must be guaranteed by a bank or trust company. Officers
of corporations and those acting in a fiduciary or other representative capacity
should file proper evidence of authority to assign the foregoing Warrant.

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00050-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00050-of-00352.parquet"}]]