Document:

Exhibit 10.28

 

LEASE AGREEMENT

 

THIS LEASE AGREEMENT (“this
Lease”) is made as of this 15th day of November, 2013, between ARE-MARYLAND NO. 30, LLC, a Maryland
limited liability company (“Landlord”), and GENVEC, INC., a Delaware corporation (“Tenant”).

 

BASIC LEASE PROVISIONS

 

		Address:	Suite 220N, 910 Clapper Road, Gaithersburg, Maryland 20878.

 

		Premises:	That portion of the Project, containing approximately 6,489 rentable square feet, as determined
by Landlord, as shown on Exhibit A, Gaudreau, Inc., Landlord’s architect, has measured the area of the Premises
pursuant to the 1996 Standard Method of Measuring Floor Area in Office Buildings as adopted by the Building Owners and Managers
Association (ANSI/BOMA Z65.1-1996) (“BOMA Standards”). Tenant acknowledges receipt of such measurement and confirms
that (a) Tenant has had an opportunity to confirm such measurement with an architect of its selection before the Commencement Date,
and (b) such measurement shall be conclusive as to the area of the Premises.

 

		Project:	The real property on which the building (“Building”) in which the Premises are
located, together with all improvements thereon and appurtenances thereto as described on Exhibit B.

 

	Base Rent: $9,706.46, per month	Rentable Area of Premises: 6,489 sq. ft.
	 	 
	Rentable Area of Project: 180,650 sq. ft.	Tenant’s Share of Operating Expenses: 3.59%
	 	 
	Security Deposit: $97,064	Target Commencement Date: December 1, 2013
	 	 
	Rent Adjustment Percentage: 3%	 

 

	Base Term:	Beginning on the Commencement Date and ending on October 31, 2019.
	 	 
	Permitted Use:	research and development laboratory, office, manufacturing, and other related uses otherwise in compliance with the provisions of Section 7 hereof.

 

	Address for Rent Payment:	Landlord’s Notice Address:
	For check payments remit to:	385 E. Colorado Blvd., Suite 299
	 	Pasadena, CA 91101
	SunTrust Bank	Attention: Corporate Secretary
	P.O. Box 79840	 
	Baltimore, MD 21279-0840	 

 

For overnight courier remit to:

 

Lockbox # 79840

c/o SunTrust Bank

1000 Stewart Avenue

Glen Burnie, MD 21061

 

 

Tenant’s Notice Address:

Suite 220N

910 Clopper Road

Gaithersburg, MD 20878

Attn: General Counsel

 

     

     

    

  

With a copy (which shall not constitute notice)

to:

Hogan Lovells, US, LLP

555 13th Street, NW

Washington, D.C. 20004

Attn: Howard Rosenstock

 

The following Exhibits and Addenda are attached hereto and incorporated
herein by this reference:

 

	x EXHIBIT A – PREMISES DESCRIPTION	x EXHIBIT B – DESCRIPTION OF PROJECT
	x EXHIBIT C – WORK LETTER	x EXHIBIT D – COMMENCEMENT DATE
	x EXHIBIT E – RULES AND REGULATIONS	x EXHIBIT F – TENANT’S PERSONAL PROPERTY
	x EXHIBIT G – NOTIFICATION OF THE	 
	PRESENCE OF ASBESTOS CONTAINING	 
	MATERIALS	 

 

1.       Lease
of Premises. Upon and subject to all of the terms and conditions hereof, Landlord hereby leases
the Premises to Tenant and Tenant hereby leases the Premises from Landlord. The portions of the Project which are for the non-exclusive
use of tenants of the Project are collectively referred to herein as the “Common Areas.” Landlord reserves the
right to modify Common Areas, provided that such modifications do not materially adversely affect Tenant’s use of the Premises
for the Permitted Use.

 

2.       Delivery;
Acceptance of Premises; Commencement Date. Landlord shall use reasonable efforts to deliver
the Premises to Tenant on or before the Target Commencement Date, with Landlord’s Work Substantially Complete (“Delivery”
or “Deliver”). If Landlord fails to timely Deliver the Premises, Landlord shall not be liable to Tenant for
any loss or damage resulting therefrom, and this Lease shall not be void or voidable except as provided herein. If Landlord does
not Deliver the Premises within 20 days of the Target Commencement Date for any reason other than Force Majeure Delays, this Lease
may be terminated by Tenant by written notice to Landlord, and if so terminated: (a) the Security Deposit, or any balance thereof
(i.e., after deducting therefrom all amounts to which Landlord is entitled under the provisions of this Lease), shall be returned
to Tenant, and (b) neither Landlord nor Tenant shall have any further rights, duties or obligations under this Lease, except with
respect to provisions which expressly survive termination of this Lease. As used herein, (i) “Landlord’s Work”
means the work to the Premises to be performed by Landlord described on Exhibit C, (ii) “Force Majeure Delays”
means delays arising by reason of any Force Majeure (as defined in Section 34), and (iii) “Substantially Completed”
or “Substantially Complete” means the substantial completion of Landlord’s Work (A) in a good and workmanlike
manner, (B) in accordance with the requirements described in Exhibit C, and (C) in accordance with all applicable Legal
Requirements (as defined in Section 7 hereof), subject only to normal “punch list” items that do not materially
impair Tenant’s use and enjoyment of the Premises. If Tenant shall not elect to void this Lease within 5 business days of
the lapse of such 20 day period, such right to void this Lease shall be waived and this Lease shall remain in full force and effect.

 

The “Commencement
Date” shall mean the date of this Lease. The “Rent Commencement Date” shall be December 1, 2013. Upon
request of Landlord, Tenant shall execute and deliver a written acknowledgment of the Commencement Date, the Rent Commencement
Date, and the expiration date of the Term when such are established in the form of the “Acknowledgement of Commencement Date”
attached to this Lease as Exhibit D; provided, however, Tenant’s failure to execute and deliver such
acknowledgment shall not affect Landlord’s rights hereunder. The “Term” of this Lease shall be the Base
Term, as defined above in the Basic Lease Provisions, and the Extension Term that Tenant may elect pursuant to Section 39
hereof.

 

Except as set forth in
the Work Letter, if applicable: (i) Tenant shall accept the Premises in their condition as of the Commencement Date, subject to
all applicable Legal Requirements; (ii) Landlord shall have no obligation for any defects in the Premises (other than matters of
maintenance and repair for which Landlord is expressly responsible under this Lease); and (iii) Tenant’s taking possession
of the Premises shall be conclusive evidence that Tenant accepts the Premises and that the Premises were in good condition at the
time possession was taken. Tenant may occupy the Premises after the Commencement Date; provided, however, that any
such occupancy of the Premises by Tenant after the Commencement Date shall be subject to all of the terms and conditions of this
Lease. The Premises shall include the following located in the Premises as of the Rent Commencement Date: furniture,

 

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fixed and non-moveable cabinetry and casework,
chemical fume hood, bench tops, and other movable laboratory equipment; provided, however, that Tenant shall have
the right, by no later than 5 business days before the Rent Commencement Date, to send notice to Landlord to remove all or any
part of the furniture located in the Premises, whereupon Landlord shall remove such furniture from the Premises at its sole cost
and expense within 15 days after receipt of such notice. If Tenant does not timely exercise its right to request Landlord to remove
such furniture, such furniture, together with such fixed and non-moveable cabinetry and casework, chemical fume hood, bench tops,
and other movable laboratory equipment located in the Premises shall be surrendered to Landlord on the expiration or earlier termination
of this Lease in good condition and repair, ordinary wear and tear excepted, and otherwise in accordance with the provisions of
this Lease.

 

Tenant agrees and acknowledges
that, except as set forth in the Work Letter, neither Landlord nor any agent of Landlord has made any representation or warranty
with respect to the condition of all or any portion of the Premises or the Project, and/or the suitability of the Premises or the
Project for the conduct of Tenant’s business, and Tenant waives any implied warranty that the Premises or the Project are
suitable for the Permitted Use. This Lease constitutes the complete agreement of Landlord and Tenant with respect to the subject
matter hereof and supersedes any and all prior representations, inducements, promises, agreements, understandings and negotiations
which are not contained herein. Landlord in executing this Lease does so in reliance upon Tenants representations, warranties,
acknowledgments and agreements contained herein.

 

3.        Rent.

 

(a)       Base
Rent. The first month’s Base Rent and the Security Deposit shall be due and payable on
delivery of an executed copy of this Lease to Landlord. Beginning on the Rent Commencement Date (but subject to the Rental Abatement
[as defined in Section 4]), Tenant shall pay to Landlord in advance, without demand, abatement, deduction or set-off, monthly
installments of Base Rent on or before the first day of each calendar month during the Term hereof, in lawful money of the United
States of America, at the office of Landlord for payment of Rent set forth above, or to such other person or at such other place
as Landlord may from time to time designate in writing. Payments of Base Rent for any fractional calendar month shall be prorated.
The obligation of Tenant to pay Base Rent and other sums to Landlord and the obligations of Landlord under this Lease are independent
obligations. Tenant shall have no right at any time to abate, reduce, or set-off any Rent (as defined in Section 5) due
hereunder except for any abatement as may be expressly provided in this Lease.

 

(b)       Additional
Rent. In addition to Base Rent, Tenant agrees to pay to Landlord as additional rent (“Additional
Rent”): (i) Tenant’s Share of “Operating Expenses” (as defined in Section 5), and (ii) any and
all other amounts Tenant assumes or agrees to pay under the provisions of this Lease, including, without limitation, any and all
other sums that may become due by reason of any default of Tenant or failure to comply with the agreements, terms, covenants and
conditions of this Lease to be performed by Tenant, after any applicable notice and cure period.

 

4.       Base
Rent Adjustments. Base Rent shall be increased on each anniversary of the first day of the
first full month during the Term of this Lease (each an “Adjustment Date”) by multiplying the Base Rent payable
immediately before such Adjustment Date by the Rent Adjustment Percentage and adding the resulting amount to the Base Rent payable
immediately before such Adjustment Date. Base Rent, as so adjusted, shall thereafter be due as provided herein. Base Rent adjustments
for any fractional calendar month shall be prorated.

 

(a)       Provided
Tenant is not in Default hereunder. Landlord hereby grants Tenant an abatement (“Rental
Abatement”) of the Base Rent and Tenants Share of Operating Expenses (but Tenant shall pay the cost of any electricity
consumed within the Premises from and after the Rent Commencement Date) payable hereunder for the period beginning on the Rent
Commencement Date and ending on October 31, 2014. Thereafter, Tenant shall pay the full amount of Base Rent and Tenant’s
Share of Operating Expenses due in accordance with the provisions of this Lease. Notwithstanding anything to the contrary in this
Section 4(a) the adjustment in the Base Rent as set forth in this Section 4 shall be based on the full and unabated
amount of Base Rent payable for the 12 month period from and after the Rent Commencement Date.

 

5.       Operating
Expense Payments. Landlord shall deliver to Tenant a written estimate of Operating Expenses
for each calendar year during the Term (“Annual Estimate”), which may be revised by Landlord from

 

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time to time during such calendar year. Beginning
on the Rent Commencement Date (but subject to the Rental Abatement), Tenant shall pay Landlord on or before the first day of each
calendar month during the Term hereof an amount equal to 1/12th of Tenant’s Share of the Annual Estimate. Payments
for any fractional calendar month shall be prorated.

 

The term “Operating
Expenses” means all costs and expenses of any kind or description whatsoever incurred or accrued each calendar year by Landlord
with respect to the Project (including, without duplication, Taxes (as defined in Section 9) capital repairs and improvements
amortized over the lesser of 10 years and the useful life of such capital items, and the costs of Landlord’s third party
property manager or, if there is no third party property manager, administration rent, but such management cost shall not exceed
an amount equal to 4% of Base Rent), excluding only:

 

(a)       the
original construction costs of the Project and renovation prior to the date of this Lease and costs of correcting defects in such
original construction or renovation;

 

(b)       capital
expenditures for expansion of the Project;

 

(c)       interest,
principal payments of Mortgage (as defined in Section 27) debts of Landlord, financing costs and amortization of funds borrowed
by Landlord, whether secured or unsecured and all payments of base rent (but not taxes or operating expenses) under any ground
lease or other underlying lease of all or any portion of the Project;

 

(d)       depreciation
of the Project (except for capital improvements, the cost of which are includable in Operating Expenses);

 

(e)       advertising,
legal and space planning expenses and leasing commissions and other costs and expenses incurred in procuring and leasing space
to tenants for the Project, including any leasing office maintained in the Project, free rent and construction allowances for tenants;

 

(f)       legal
and other expenses incurred in the negotiation or enforcement of leases;

 

(g)       completing,
fixturing, improving, renovating, painting, redecorating or other work, which Landlord pays for or performs for other tenants within
their premises, and costs of correcting defects in such work:

 

(h)       costs
of utilities outside normal business hours sold to tenants of the Project;

 

(i)       costs
to be reimbursed by other tenants of the Project or Taxes to be paid directly by Tenant or other tenants of the Project, whether
or not actually paid;

 

(j)       salaries,
wages, benefits and other compensation paid to officers and employees of Landlord who are not assigned in whole or in part to the
operation, management, maintenance or repair of the Project;

 

(k)       general
organizational, administrative and overhead costs relating to maintaining Landlord’s existence, either as a corporation,
partnership, or other entity, including general corporate, legal and accounting expenses;

 

(l)       costs
(including attorneys’ fees and costs of settlement, judgments and payments in lieu thereof) incurred in connection with disputes
with tenants, other occupants, or prospective tenants, and costs and expenses, including legal fees, incurred in connection with
negotiations or disputes with employees, consultants, management agents, leasing agents, purchasers or mortgagees of the Building;

 

(m)       costs
incurred by Landlord due to the violation by Landlord, its employees, agents or contractors or any tenant of the terms and conditions
of any lease of space in the Project or any Legal Requirement (as defined in Section 7);

 

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(n)       penalties,
fines or interest incurred as a result of Landlord’s inability or failure to make payment of Taxes and/or to file any tax
or informational returns when due, or from Landlord’s failure to make any payment of Taxes required to be made by Landlord
hereunder before delinquency;

 

(o)       overhead
and profit increment paid to Landlord or to subsidiaries or affiliates of Landlord for goods and/or services in or to the Project
to the extent the same exceeds the costs of such goods and/or services rendered by unaffiliated third parties on a competitive
basis;

 

(p)       costs
of Landlord’s charitable or political contributions, or of fine art maintained at the Project;

 

(q)       costs
in connection with services (including electricity), items or other benefits of a type which are not standard for the Project and
which are not available to Tenant without specific charges therefor, but which are provided to another tenant or occupant of the
Project, whether or not such other tenant or occupant is specifically charged therefor by Landlord;

 

(r)       costs
incurred in the sale or refinancing of the Project;

 

(s)       net
income taxes of Landlord or the owner of any interest in the Project (except to the extent such net income taxes are in substitution
for any Taxes payable hereunder), franchise, capital stock, gift, estate or inheritance taxes or any federal, state or local documentary
taxes imposed against the Project or any portion thereof or interest therein; and

 

(t)       any
expenses otherwise includable within Operating Expenses to the extent actually reimbursed by persons other than tenants of the
Project under leases for space in the Project.

 

Notwithstanding any contrary
provision contained in this Section 5, each line item of the Controllable Operating Expenses (as defined below) shall be
capped so that no increase in any calendar year, on a line-item basis, exceeds 10% over the prior year’s line-item amount
on a non-cumulative basis. As a result, the actual annual increase in each line item of Controllable Operating Expenses in any
given calendar year from and after calendar year 2014 may be less than or equal to 10% (but shall not exceed 10% in any such year).
For purposes of this Lease, “Controllable Operating Expenses” means all Operating Expenses except real estate taxes,
utilities, snow and ice removal, and insurance premiums (provided insurance costs are competitively bid annually) (such exceptions
collectively referred to herein as the “Non-Controllable Operating Expenses”).

 

Within 90 days after the
end of each calendar year (or such longer period as may be reasonably required), Landlord shall furnish to Tenant a statement (an
“Annual Statement”) showing in reasonable detail: (a) the total and Tenant’s Share of actual Operating
Expenses for the previous calendar year. and (b) the total of Tenant’s payments in respect of Operating Expenses for such
year. If Tenant’s Share of actual Operating Expenses for such year exceeds Tenant’s payments of Operating Expenses
for such year, the excess shall be due and payable by Tenant as Rent within 30 days after delivery of such Annual Statement to
Tenant. If Tenant’s payments of Operating Expenses for such year exceed Tenant’s Share of actual Operating Expenses
for such year Landlord shall pay the excess to Tenant within 30 days after delivery of such Annual Statement, except that after
the expiration, or earlier termination of the Term or if Tenant is delinquent in its obligation to pay Rent, Landlord shall pay
the excess to Tenant after deducting all other amounts due Landlord.

 

The Annual Statement shall
be final and binding upon Tenant unless Tenant, within 180 days after Tenant’s receipt thereof, shall contest any item therein
by giving written notice to Landlord, specifying each item contested and the reason therefor. If, during such 180 day period, Tenant
reasonably and in good faith questions or contests the accuracy of Landlord’s statement of Tenant’s Share of Operating
Expenses, Landlord will provide Tenant with access to Landlord’s books and records relating to the operation of the Project
and such reasonable additional information as appropriate to be responsive to any Tenant’s questions (“Expense Information”).
If after Tenant’s review of such Expense Information, Landlord and Tenant cannot agree upon the amount of Tenant’s
Share of Operating Expenses, then Tenant shall have the right to have an independent public accounting firm selected by Tenant
from among the 5 largest (as measured by the number of certified public accountants) operating in the greater Washington, D.C.
metropolitan area, working pursuant to a fee arrangement other than a contingent fee (at

 

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Tenant’s sole cost and expense) and approved
by Landlord (which approval shall not be unreasonably withheld or delayed), audit and/or review the Expense Information for the
year in question (“Independent Review”). The results of any such Independent Review shall be binding on Landlord
and Tenant. If the Independent Review shows that the payments actually made by Tenant with respect to Operating Expenses for the
calendar year in question exceeded Tenant’s Share of Operating Expenses for such calendar year, Landlord shall at Landlord’s
option either (i) credit the excess amount to the next succeeding installments of estimated Operating Expenses or (ii) pay the
excess to Tenant within 30 days after delivery of such statement, except that after the expiration or earlier termination of this
Lease or if Tenant is delinquent in its obligation to pay Rent, Landlord shall pay the excess to Tenant after deducting all other
amounts due Landlord. If the Independent Review shows that Tenant’s payments with respect to Operating Expenses for such
calendar year were less than Tenant’s Share of Operating Expenses for the calendar year, Tenant shall pay the deficiency
to Landlord within 30 days after delivery of such statement. If the Independent Review shows that Tenant has overpaid with respect
to Operating Expenses by more than 5% in any calendar year then Landlord shall reimburse Tenant for all costs, expenses, and fees
(including reasonable attorneys’ fees) incurred by Tenant for the Independent Review. Operating Expenses for the calendar
years in which Tenant’s obligation to share therein begins and ends shall be prorated. Notwithstanding anything set forth
herein to the contrary, if the Project is not at least 95% occupied on average during any year of the Term, Tenant’s Share
of Operating Expenses for such year shall be computed as though the Project had been 95% occupied on average during such year,
with appropriate adjustment of only those Operating Expenses that vary with occupancy.

 

“Tenant’s Share”
shall be the percentage set forth in the Basic Lease Provisions as Tenant’s Share as reasonably adjusted by Landlord for
changes in the physical size of the Premises or the Project occurring thereafter. Landlord may charge Tenant separately for any
item of expense or cost reimbursable by Tenant that relates to a repair, replacement, or service that benefits only the Premises
or that varies with occupancy or use. Base Rent, Tenant’s Share of Operating Expenses and ail other amounts payable by Tenant
to Landlord hereunder are collectively referred to herein as “Rent.”

 

6.       Security
Deposit. Tenant shall deposit with or provide to Landlord, upon delivery of an executed copy
of this Lease to Landlord, a security deposit (“Security Deposit”) for the performance of all of Tenant’s
obligations hereunder in the amount set forth in the Basic Lease Provisions, which Security Deposit shall be in the form of an
unconditional and irrevocable letter of credit (“Letter of Credit”): (i) in form and substance satisfactory
to Landlord, (ii) naming Landlord as beneficiary, (iii) expressly allowing Landlord to draw upon it at any time from time to time
by delivering to the issuer notice that Landlord is entitled to draw thereunder, (iv) issued by an FDIC-insured financial institution
satisfactory to Landlord, and (v) redeemable by presentation of a sight draft in the state of Maryland. If Tenant does not provide
Landlord with a substitute Letter of Credit complying with ail of the requirements hereof at least 10 days before the stated expiration
date of any then current Letter of Credit, Landlord shall have the right to draw the full amount of the current Letter of Credit
and hold or apply the funds drawn in cash without obligation for interest thereon as the Security Deposit. The Security Deposit
shall be held by Landlord as security for the performance of Tenant’s obligations under this Lease. The Security Deposit
is not an advance rental deposit or a measure of Landlord’s damages in case of Tenant’s default. Upon the occurrence
of a Default (as defined in Section 20), Landlord may use all or any part of the Security Deposit to pay delinquent payments
due under this Lease and any other charges, liabilities, or amounts owing under this Lease, and the cost of any damage, injury,
expense or liability caused by such Default, without prejudice to any other remedy provided herein or provided by law. Upon any
such use of all or any portion of the Security Deposit and except as otherwise provided in the last paragraph of this Section,
Tenant shall pay Landlord on demand the amount that will restore the Security Deposit to the amount set forth in the Basic Lease
Provisions. Tenant hereby waives the provisions of any law, now or hereafter in force, which provide that Landlord may claim from
a security deposit only those sums reasonably necessary to remedy defaults in the payment of Rent, to repair damage caused by Tenant
or to clean the Premises, it being agreed that Landlord may, in addition, claim those sums owing under this Lease and any other
sums reasonably necessary to compensate Landlord for any other loss or damage, foreseeable or unforeseeable, caused by the act
or omission of Tenant or any officer, employee, agent or invitee of Tenant. Upon bankruptcy or other debtor-creditor proceedings
involving Tenant, the Security Deposit shall be deemed to be applied first to the payment of Rent (including, but not limited to,
any Rental Abatement) and other charges due Landlord for periods prior to the filing of such proceedings. Upon any such use of
all or any portion of the Security Deposit, Tenant shall, within 5 days after demand from Landlord, restore the Security Deposit
to its original amount. If Tenant shall fully perform every provision of this Lease to be performed by Tenant, the Security Deposit,
or any balance thereof (i.e., after deducting therefrom all amounts to which Landlord is entitled under the provisions of this
Lease), shall be returned

 

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to Tenant (or, at Landlord’s option,
to the last assignee of Tenant’s interest hereunder) within 60 days after the expiration or earlier termination of this Lease.

 

If Landlord transfers its
interest in the Project or this Lease, Landlord shall either (a) transfer any Security Deposit then held by Landlord to a person
or entity assuming Landlord’s obligations under this Section 6, or (b) return to Tenant any Security Deposit then
held by Landlord and remaining after the deductions permitted herein. Upon such transfer to such transferee or the return of the
Security Deposit to Tenant, Landlord shall have no further obligation with respect to the Security Deposit, and Tenant’s
right to the return of the Security Deposit shall apply solely against Landlord’s transferee. The Security Deposit is not
an advance rental deposit or a measure of Landlord’s damages in case of Tenant’s default. Landlord’s obligation
respecting the Security Deposit is that of a debtor, not a trustee, and no interest shall accrue thereon.

 

The Security Deposit shall
be reduced in accordance with the following conditions and schedule: (i) if Tenant has not been in Default for the first 36 month
period of the Base Term, the Security Deposit shall be reduced by an amount equal to $38,825.84, and (ii) if Tenant has not been
in Default for the first 48 month period of the Base Term, the Security Deposit shall be further reduced by an amount equal to
$38,825.84 (as reduced, the “Reduced Security Deposit”). Except as otherwise provided in this paragraph, if
Landlord returns to Tenant any portion of the Security Deposit in accordance with this Section, then from and after the date such
monies are returned to Tenant, the “Security Deposit” shall be deemed to be the Reduced Security Deposit for all purposes
of this Lease. The foregoing reduction shall be effectuated by Tenant replacing the Letter of Credit then being held by Landlord
with a new Letter of Credit (complying with the terms of this Lease) in the amount then required to be maintained with Landlord
pursuant to the foregoing provisions (or amending the then existing Letter of Credit to the amount then required to be maintained
with Landlord pursuant to the foregoing provisions). The Reduced Security Deposit shall be increased in accordance with the terms
of this Section if Tenant is in Default hereunder on more than 2 occasions after such reduction, If Tenant is in Default hereunder
on more than 2 occasions after such reduction, the Security Deposit shall be increased to its original amount. Such increased Security
Deposit shall be paid or delivered to Landlord within 10 days of Landlord’s written demand. If Tenant is required to increase
the Reduced Security Deposit in accordance with this Section, then from and after the date such monies or Letter of Credit are
deposited with Landlord, the “Security Deposit” shall be deemed to be the amount then held by Landlord hereunder.

 

7.       Use.
The Premises shall be used solely for the Permitted Use set forth in the Basic Lease Provisions, and in compliance with all laws,
orders, judgments, ordinances, regulations, codes, directives, permits, licenses, covenants and restrictions now or hereafter applicable
to the Premises, and to the use and Occupancy thereof, including, without limitation, the Americans With Disabilities Act, 42 U.S.C.
§ 12101, et seq. (together with the regulations promulgated pursuant thereto, “ADA”) (collectively, “Legal
Requirements” and each, a “Legal Requirement”). Tenant shall, upon 7 days’ written notice from
Landlord, discontinue any use of the Premises which is declared by any Governmental Authority (as defined in Section 9)
having jurisdiction to be a violation of a Legal Requirement. Tenant will not use or permit the Premises to be used for any purpose
or in any manner that would void Tenant’s or Landlord’s insurance, increase the insurance risk, or cause the disallowance
of any sprinkler or other credits. Tenant shall not permit any part of the Premises to be used as a “place of public accommodation”,
as defined in the ADA or any similar legal requirement. Tenant shall reimburse Landlord promptly upon demand for any additional
premium charged for any such insurance policy by reason of Tenant’s failure to comply with the provisions of this Section
or otherwise caused by Tenant’s use and/or occupancy of the Premises. Tenant will use the Premises in a careful, safe and
proper manner and will not commit or permit waste, overload the floor or structure of the Premises, subject the Premises to use
that would damage the Premises or obstruct or interfere with the rights of Landlord or other tenants or occupants of the Project,
including conducting or giving notice of any auction, liquidation, or going out of business sale on the Premises, or using or allowing
the Premises to be used for any unlawful purpose. Tenant shall cause any equipment or machinery to be installed in the Premises
so as to reasonably prevent sounds or vibrations from the Premises from extending into Common Areas, or other space in the Project.
Tenant shall not place any machinery or equipment weighing 500 pounds or more in or upon the Premises or transport or move such
items through the Common Areas of the Project or in the Project elevators without the prior written consent of Landlord. Except
as may be provided under the Work Letter, Tenant shall not, without the prior written consent of Landlord, use the Premises in
any manner which will require ventilation, air exchange, heating, gas, steam, electricity or water beyond the existing capacity
of the Project as proportionately allocated to the Premises based upon Tenant’s Share as usually furnished for the Permitted
Use.

 

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(a)       Modifications
to Common Areas. Landlord shall, as an Operating Expense (to the extent such Legal Requirement
is enacted after the Commencement Date and is generally applicable to similar buildings in the area in which the Project is located)
or at Tenant’s expense (to the extent such Legal Requirement is applicable solely by reason of Tenant’s, as compared
to other tenants of the Project, particular use of the Premises) make any alterations or modifications to the Common Areas or the
exterior of the Building that are required by such Legal Requirements, including the ADA. Tenant, at its sole expense, shall make
any alterations or modifications to the interior of the Premises that are required by such Legal Requirements (including, without
limitation, compliance of the Premises with the ADA. Notwithstanding any other provision herein to the contrary, Tenant shall be
responsible for any and all demands, claims, liabilities, losses, costs, expenses, actions, causes of action, damages or judgments,
and all reasonable expenses incurred in investigating or resisting the same (including, without limitation, reasonable attorneys’
fees, charges and disbursements and costs of suit) (collectively, “Claims”) arising out of or in connection with Legal
Requirements, and Tenant shall indemnify, defend, hold and save Landlord harmless from and against any and all Claims arising out
of or in connection with any failure of the Premises to comply with any Legal Requirement.

 

8.       Holding
Over. If, with Landlord’s express written consent, Tenant retains possession of the Premises
after the termination of the Term, (i) unless otherwise agreed in such written consent, such possession shall be subject to immediate
termination by Landlord at any time, (ii) all of the other terms and provisions of this Lease (including, without limitation, the
adjustment of Base Rent pursuant to Section 4 hereof) shall remain in full force and effect (excluding any expansion or
renewal option or other similar right or option) during such holdover period, (Si) Tenant shall continue to pay Base Rent in the
amount payable upon the date of the expiration or earlier termination of this Lease or such other amount as Landlord may indicate,
in Landlord’s sole and absolute discretion, in such written consent, and (iv) all other payments shall continue under the
terms of this Lease. If Tenant remains in possession of the Premises after the expiration or earlier termination of the Term without
the express written consent of Landlord, (A) Tenant shall become a tenant at sufferance upon the terms of this Lease except that
the monthly rental shall be equal to 150% of Base Rent (plus 100% of Operating Expenses) in effect during the last 30 days of the
Term, and (B) Tenant shall be responsible for all damages suffered by Landlord resulting from or occasioned by Tenant’s holding
over (including, from and after 60 days after the end of the Term, consequential damages if Landlord has advised Tenant in advance
of any particular consequential damages that Landlord may incur or suffer as a result of Tenant’s holding over, including,
without limitation, consequential damages that Landlord may incur or suffer by reason of Landlord’s inability to lease the
Premises or deliver occupancy to a particular tenant). No holding aver by Tenant, whether with or without consent of Landlord,
shall operate to extend this Lease except as otherwise expressly provided, and this Section 8 shall not be construed as
consent for Tenant to retain possession of the Premises. Acceptance by Landlord of Rent after the expiration of the Term or earlier
termination of this Lease shall not result in a renewal or reinstatement of this Lease.

 

9.       Taxes.
Landlord shall pay, as part of Operating Expenses, all taxes, levies, fees, assessments and governmental charges of any kind, existing
as of the Commencement Date or thereafter enacted (collectively referred to as “Taxes”), imposed by any federal,
state, regional, municipal, local or other governmental authority or agency upon the Project, including, without limitation, quasi-public
agencies (collectively, “Governmental Authority”) during the Term, including, without limitation, all Taxes:
(i) imposed on or measured by or based, in whole or in part, on rent payable to (or gross receipts received by) Landlord under
this Lease and/or from the rental by Landlord of the Project or any portion thereof, or (ii) based on the square footage, assessed
value or other measure or evaluation of any kind of the Premises or the Project, or (iii) assessed or imposed by or on the operation
or maintenance of any portion of the Premises or the Project, including parking, or (iv) assessed or imposed by, or at the direction
of, or resulting from Legal Requirements, or interpretations thereof, promulgated by any Governmental Authority, or (v) imposed
as a license or other fee, charge, tax, or assessment on Landlord’s business or occupation of leasing space in the Project.
Landlord may contest by appropriate legal proceedings the amount, validity, or application of any Taxes or liens securing Taxes.
Taxes shall not include any net income taxes imposed on Landlord except to the extent such net income taxes are in substitution
for any Taxes payable hereunder. If any such Tax is levied or assessed directly against Tenant, then Tenant shall be responsible
for and shall pay the same at such times and in such manner as the taxing authority shall require. Tenant shall pay, prior to delinquency,
any and all Taxes levied or assessed against any personal property or trade fixtures placed by Tenant in the Premises, whether
levied or assessed against Landlord or Tenant. If any Taxes on Tenant’s personal property or trade fixtures are levied against
Landlord or Landlord’s property, or if the assessed valuation of the Project is increased by a value attributable to improvements
in or alterations to the Premises, whether owned by Landlord or Tenant and whether or

 

    	 	8	 

     

    

  

not affixed to the real property so as to become
a part thereof, higher than the base valuation on which Landlord from time-to-time allocates Taxes to all tenants in the Project,
Landlord shall have the right, but not the obligation, to pay such Taxes. Landlord’s determination of any excess assessed
valuation shall be binding and conclusive, absent manifest error. The amount of any such payment by Landlord shall constitute Additional
Rent due from Tenant to Landlord immediately upon demand.

 

10.       Parking.
Subject to all Legal Requirements, Force Majeure, a Taking (as defined in Section 19 below) and the exercise by Landlord
of its rights hereunder, Tenant shall have the right, at no cost or fee to Tenant and in common with other tenants of the Project
pro rata in accordance with the rentable area of the Premises and the rentable areas of the Project occupied by such other tenants,
to park in those areas designated for non-reserved parking, subject in each case to Landlord’s rules and regulations. Landlord
may allocate parking spaces among Tenant and other tenants in the Project pro rata as described above if Landlord determines that
such parking facilities are becoming crowded. Landlord shall not be responsible for enforcing Tenant’s parking rights against
any third parties, including other tenants of the Project. As of the Commencement Date, the current parking ratio is 3.6 standard
sized spaces per 1,000 leased rentable square feet.

 

11.       Utilities,
Services. Landlord shall provide, subject to the terms of this Section 11, janitorial
services to the Common Areas, water, electricity, heat, light, power, telephone, sewer, and other utilities (including gas and
fire sprinklers to the extent the Project is plumbed for such services), and refuse and trash collection (collectively, “Utilities’’).
Landlord shall pay, as Operating Expenses or subject to Tenant’s reimbursement obligation, for all Utilities used on the
Project, all maintenance charges for Utilities, and any storm sewer charges or other similar charges for Utilities imposed by any
Governmental Authority or Utility provider, and any taxes, penalties, surcharges or similar charges thereon. Landlord may cause,
at its expense, any Utilities serving the Premises to be separately metered or charged directly to Tenant by the provider. Tenant
shall pay directly to the Utility provider, prior to delinquency, any separately metered Utilities and services which may be furnished
to Tenant or the Premises during the Term. Tenant shall pay, as part of Operating Expenses, its share of all charges for jointly
metered Utilities based upon consumption, as reasonably determined by Landlord. No interruption or failure of Utilities, from any
cause whatsoever other than Landlord’s willful misconduct, shall result in eviction or constructive eviction of Tenant, termination
of this Lease or the abatement of Rent. Tenant agrees to limit use of water and sewer with respect to Common Areas to normal restroom
use.

 

12.       Alterations
and Tenant’s Property. Any alterations, additions, or improvements made to the Premises by or on behalf of Tenant, including
additional locks or bolts of any kind or nature upon any doors or windows in the Premises, but excluding installation, removal
or realignment of furniture systems (other than removal of furniture systems owned or paid for by Landlord) not involving any modifications
to the structure or connections (other than by ordinary plugs or jacks) to Building Systems (as defined in Section 13) (“Alterations”)
shall be subject to Landlord’s prior written consent, which may be given or withheld in Landlord’s sole discretion
if any such Alteration affects the structure or Building Systems, but which shall otherwise not be unreasonably withheld, conditioned
or delayed. Notwithstanding the foregoing, Tenant may elect to modify the Premises in the future and build out a higher ratio of
office to lab or lab to office. Tenant’s design and construction of all future modifications shall be in accordance with
plans and drawing approved by Landlord, which approval shall not be unreasonably withheld, conditioned or delayed. if Landlord
approves any Alterations, Landlord may impose reasonable conditions on Tenant in connection with the commencement, performance
and completion of such Alterations. Any request for approval shall be in writing, delivered not less than 10 days in advance of
any proposed construction, and accompanied by plans, specifications, bid proposals, work contracts and such other information concerning
the nature and cost of the alterations as may be reasonably requested by Landlord, including the identities and mailing addresses
of all persons performing work or supplying materials. Landlord’s right to review plans and specifications and to monitor
construction shall be solely for its own benefit, and Landlord shall have no duty to ensure that such plans and specifications
or construction comply with applicable Legal Requirements. Tenant shall cause, at its sole cost and expense, all Alterations to
comply with insurance requirements and with Legal Requirements and shall implement at its sole cost and expense any alteration
or modification required by Legal Requirements as a result of any Alterations. Except regarding initial Alterations (which shall
not be subject to any Landlord charge or fee) Tenant shall pay to Landlord, as Additional Rent, on demand an amount equal to Landlord’s
actual costs (not to exceed 4% of all hard costs incurred by Tenant or its contractors or agents) in connection with any Alteration
to cover Landlord’s overhead and expenses for plan review, coordination, scheduling and supervision. Before Tenant begins
any Alteration, Landlord may post on and about the Premises notices of non-

 

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responsibility pursuant to applicable law.
Tenant shalt reimburse Landlord for, and indemnify and hold Landlord harmless from, any expense incurred by Landlord by reason
of faulty work done by Tenant or its contractors or inadequate cleanup.

 

Tenant shall furnish security
or make other arrangements satisfactory to Landlord to assure payment for the completion of all Alterations work free and clear
of liens, and shall provide (and cause each contractor or subcontractor to provide) certificates of insurance (in form and substance
satisfactory to Landlord; form ACORD 28 [2006/07] is not satisfactory to Landlord) for workers’ compensation and other coverage
in amounts and from an insurance company satisfactory to Landlord protecting Landlord against liability for personal injury or
property damage during construction. Upon completion of any Alterations, Tenant shall deliver to Landlord: (i) sworn statements
setting forth the names of all contractors and subcontractors who did the work and final lien waivers from all such contractors
and subcontractors; and (ii) ‘‘as built’ plans for any such Alteration,

 

Other than (i) the items,
if any, listed on Exhibit F attached hereto, (ii) any items agreed by Landlord in writing to be included on Exhibit F
in the future, and (iii) any trade fixtures, machinery, equipment and other personal property not paid for by Landlord that may
be removed without material damage to the Premises, which damage shall be repaired (including capping or terminating utility hookups
behind walls) by Tenant during the Term (collectively, “Tenant’s Property”), ail property of any kind
paid for by Landlord, all Alterations, real property fixtures, built-in machinery and equipment, built-in casework and cabinets
and other similar additions and improvements built into the Premises so as to become an integral part of the Premises such as fume
hoods which penetrate the roof or plenum area, built-in cold rooms, built-in warm rooms, walk-in cold rooms, walk-in warm rooms,
deionized water systems, glass washing equipment, autoclaves, chillers, built-in plumbing, electrical and mechanical equipment
and systems, and any power generator and transfer switch (collectively, “Installations”) shall be and shall
remain the property of Landlord during the Term and following the expiration or earlier termination of the Term, shall not be removed
by Tenant at any time during the Term and shalt remain upon and be surrendered with the Premises as a part thereof in accordance
with Section 28 following the expiration or earlier termination of this Lease; provided, however, that Landlord
shall, at the time its approval of such Installation is requested, notify Tenant if it has elected to cause Tenant to remove such
Installation upon the expiration or earlier termination of this Lease; provided, further, however, that Tenant
need not remove, and such Landlord election shall not apply to (y) any Installation that is in the Premises on the Commencement
Date, and (z) the Generator (as defined below). Subject to the immediately preceding sentence, if Landlord so elects, Tenant shall
remove such Installation upon the expiration or earlier termination of this Lease and restore any damage caused by or occasioned
as a result of such removal, including, when removing any of Tenant’s Property which was plumbed, wired or otherwise connected
to any of the Building Systems, capping off all such connections behind the walls of the Premises and repairing any holes. During
any such restoration period, Tenant shall pay Rent to Landlord as provided herein as if said space were otherwise occupied by Tenant.

 

13.       Landlord’s
Repairs. Landlord, as an Operating Expense, shall maintain all of the structural, exterior,
parking and other Common Areas of the Project, including HVAC, plumbing, fire sprinklers, elevators and all other building systems
serving the Premises and other portions of the Project (“Building Systems”), in good repair, reasonable wear
and tear and uninsured losses and damages caused by Tenant, or by any of Tenant’s agents, servants, employees, invitees and
contractors (collectively, “Tenant Parties”) excluded. Losses and damages caused by Tenant or any Tenant Party
shall be repaired by Landlord, to the extent not covered by insurance, at Tenant’s sole cost and expense. Landlord reserves
the right to stop Building Systems services when necessary (i) by reason of accident or emergency, or (ii) for planned repairs,
alterations or improvements, which are, in the judgment of Landlord, desirable or necessary to be made, until said repairs, alterations
or improvements shall have been completed, Landlord shall have no responsibility or liability for failure to supply Building Systems
services during any such period of interruption; provided, however, that Landlord shall, except in case of emergency,
make a commercially reasonable effort to give Tenant 24 hours advance notice of any planned stoppage of Building Systems services
for routine maintenance, repairs, alterations or improvements. Tenant shall promptly give Landlord written notice of any repair
required by Landlord pursuant to this Section, after which Landlord shall have a reasonable opportunity to effect such repair.
Landlord shall not be liable for any failure to make any repairs or to perform any maintenance unless such failure shall persist
for an unreasonable time after Tenant’s written notice of the need for such repairs or maintenance. Tenant waives its rights
under any state or local law to terminate this Lease or to make such repairs at Landlord’s expense and
agrees that the parties’ respective rights with respect to 

 

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such matters shall be solely as set forth herein. Repairs required
as the result of fire, earthquake, flood, vandalism, war, or similar cause of damage or destruction shall be controlled by Section
18.

 

14.       Tenant’s
Repairs. Subject to Section 13 hereof, Tenant, at its expense, shall repair, replace
and maintain in good condition all portions of the Premises, including, without limitation, entries, doors, ceilings, interior
windows, interior walls, and the interior side of demising walls. Such repair and replacement may include capital expenditures
and repairs whose benefit may extend beyond the Term. Should Tenant fail to make any such repair or replacement or fail to maintain
the Premises, Landlord shall give Tenant notice of such failure. If Tenant fails to commence cure of such failure within 10 days
of Landlord’s notice, and thereafter diligently prosecute such cure to completion, Landlord may perform such work and shall
be reimbursed by Tenant within 10 days after demand therefor; provided, however, that if such failure by Tenant creates
or could create an emergency, Landlord may immediately commence cure Of such failure and shall thereafter be entitled to recover
the costs of such cure from Tenant. Subject to Sections 17 and 18, Tenant shall bear the full uninsured cost of any
repair or replacement to any part of the Project that results from damage caused by Tenant or any Tenant Party and any repair that
benefits only the Premises.

 

15.       Mechanic’s
Liens. Tenant shall discharge, by bond or otherwise, any mechanic’s lien filed against
the Premises or against the Project for work claimed to have been done for, or materials claimed to have been furnished to, Tenant
within 10 days after the filing thereof, at Tenant’s sole cost and shall otherwise keep the Premises and the Project free
from any liens arising out of work performed, materials furnished or obligations incurred by Tenant. Should Tenant fail to discharge
any lien described herein, Landlord shall have the right, but not the obligation, to pay such claim or post a bond or otherwise
provide security to eliminate the lien as a claim against title to the Project and the cost thereof shall be immediately due from
Tenant as Additional Rent. If Tenant shall lease or finance the acquisition of office equipment, furnishings, or other personal
property of a removable nature utilized by Tenant in the operation of Tenant’s business, Tenant warrants that any Uniform
Commercial Code Financing Statement filed as a matter of public record by any lessor or creditor of Tenant will upon its face or
by exhibit thereto indicate that such Financing Statement is applicable only to removable personal property of Tenant located within
the Premises. In no event shall the address of the Project be furnished on the statement without qualifying language as to applicability
of the lien only to removable personal property, located in an identified suite held by Tenant.

 

16.       Indemnification.
Tenant hereby indemnifies and agrees to defend, save and hold Landlord harmless from and against any and all Claims for injury
or death to persons or damage to property occurring within or about the Premises, arising directly or indirectly out of use or
occupancy of the Premises or a Default by Tenant in the performance of any of its obligations hereunder, unless caused solely by
the willful misconduct or gross negligence of Landlord. Landlord shall not be liable to Tenant for, and Tenant assumes all risk
of damage to, personal property (including, without limitation, loss of records kept within the Premises). Tenant further waives
any and all Claims for injury to Tenant’s business or loss of income relating to any such damage or destruction of personal
property (including, without limitation, any loss of records). Landlord shall not be liable for any damages arising from any act,
omission or neglect of any tenant in the Project or of any other third party.

 

17.       Insurance.
Landlord shall maintain all risk property and, if applicable, sprinkler damage insurance covering the full replacement cost of
the Project or such lesser coverage amount as Landlord may elect provided such coverage amount is not less than 90% of such full
replacement cost. Landlord shall further procure and maintain commercial general liability insurance with a single loss limit of
not less than $2,000,000 for bodily injury and property damage with respect to the Project. Landlord may, but is not obligated
to, maintain such other insurance and additional coverages as it may deem necessary, including, but not limited to, flood, environmental
hazard and earthquake, loss or failure of building equipment, errors and omissions, rental loss during the period of repair or
rebuilding, workers’ compensation insurance and fidelity bonds for employees employed to perform services and insurance for
any improvements installed by Tenant or which are in addition to the standard improvements customarily furnished by Landlord without
regard to whether or not such are made a part of the Project. All such insurance shall be included as part of the Operating Expenses.
The Project may be included in a blanket policy (in which case the cost of such insurance allocable to the Project will be determined
by Landlord based upon the insurer’s cost calculations). Tenant shall also reimburse Landlord for any increased premiums
or additional insurance which Landlord reasonably deems necessary as a result of Tenant’s use of the Premises.

 

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Tenant, at its sole cost
and expense, shall maintain during the Term: all risk property insurance with business interruption and extra expense coverage,
covering the full replacement cost of all property and improvements installed or placed in the Premises by Tenant at Tenants expense;
workers’ compensation insurance with no less than the minimum limits required by law; employer’s liability insurance
with such limits as required by law; and commercial general liability insurance, with a minimum limit of not less than $2,000,000
per occurrence for bodily injury and property damage with respect to the Premises. The commercial general liability insurance policy
shall name Landlord and Alexandria Real Estate Equities, Inc., and its and their respective members, officers, directors, employees,
managers, and agents (collectively, “Landlord Parties”), as additional insureds; insure on an occurrence and
not a claims-made basis; be issued by insurance companies which have a rating of not less than policyholder rating of A and financial
category rating of at least Class VII in “Best’s Insurance Guide”; shall not be cancelable for nonpayment of
premium unless 30 days prior written notice shall have been given to Landlord from the insurer; contain a hostile fire endorsement
and a contractual liability endorsement; and provide primary coverage to Landlord (any policy issued to Landlord providing duplicate
or similar coverage shall be deemed excess over Tenant’s policies). Copies of such policies (if requested by Landlord), or
certificates of insurance (in form and substance satisfactory to Landlord; form ACORD 28 12006107) is not satisfactory to Landlord)
showing the limits of coverage required hereunder and showing Landlord as an additional insured, along with reasonable evidence
of the payment of premiums for the applicable period, shall be delivered to Landlord by Tenant upon commencement of the Term and
upon each renewal of said insurance. Tenant’s policy may be a “blanket policy” with an aggregate per location
endorsement which specifically provides that the amount of insurance shall not be prejudiced by other losses covered by the policy.
Tenant shall, at least 5 days prior to the expiration of such policies, furnish Landlord with renewal certificates.

 

In each instance where
insurance is to name Landlord as an additional insured, Tenant shall upon written request of Landlord also designate and furnish
certificates so evidencing Landlord as additional insured to: (i) any lender of Landlord holding a security interest in the Project
or any portion thereof, (ii) the landlord under any lease wherein Landlord is tenant of the real property on which the Project
is located, if the interest of Landlord is or shall become that of a tenant under a ground or other underlying lease rather than
that of a fee owner, and/or (iii) any management company retained by Landlord to manage the Project.

 

The property insurance
obtained by Landlord and Tenant shall include a waiver of subrogation by the insurers and all rights based upon an assignment from
its insured, against Landlord or Tenant, and their respective officers, directors, employees, managers, agents, invitees and contractors
(“Related Parties”), in connection with any loss or damage thereby insured against. Neither party nor its respective
Related Parties shall be liable to the other for loss or damage caused by any risk insured against under property insurance required
to be maintained hereunder, and each party waives any claims against the other party, and its respective Related Parties, for such
loss or damage. The failure of a party to insure its property shall not void this waiver. Landlord and its respective Related Parties
shall not be liable for, and Tenant hereby waives all claims against such parties for, business interruption and losses occasioned
thereby sustained by Tenant or any person claiming through Tenant resulting from any accident or occurrence in or upon the Premises
or the Project from any cause whatsoever, lithe foregoing waivers shall contravene any law with respect to exculpatory agreements,
the liability of Landlord or Tenant shall be deemed not released but shall be secondary to the other’s insurer.

 

Landlord may require insurance
policy limits to be raised to conform with requirements of Landlord’s lender and/or to bring coverage limits to levels then
being generally required of new tenants within the Project.

 

18.       Restoration.
If, at any time during the Term, the Project or the Premises are damaged or destroyed by a fire or other insured casualty, Landlord
shall notify Tenant within 60 days after discovery of such damage as to the amount of time Landlord reasonably estimates it will
take to restore the Project or the Premises, as applicable (“Restoration Period”). If the Restoration Period is estimated
to exceed 12 months (“Maximum Restoration Period”), Landlord or Tenant may, in a notice, elect to terminate
this Lease as of the date that is 75 days after the date of discovery of such damage or destruction. Unless Landlord or Tenant
so elects to terminate this Lease, Landlord shall, subject to receipt of sufficient insurance proceeds (with any deductible to
be treated as a current Operating Expense), promptly restore the Premises (excluding the improvements installed by Tenant or by
Landlord and paid for by Tenant), subject to delays arising from the collection of insurance proceeds, from Force Majeure events
or as needed to obtain any license, clearance or other authorization of any kind required to enter into and restore the Premises
issued by any Governmental Authority having jurisdiction over the use, storage, handling,

 

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treatment, generation, release, disposal, removal
or remediation of Hazardous Materials (as defined in Section 30) in, on or about the Premises (collectively referred to
herein as “Hazardous Materials Clearances”); provided, however, that if repair or restoration
of the Premises is not substantially complete as of the end of the Maximum Restoration Period or, if longer, the Restoration Period,
Landlord may, in its sole and absolute discretion, elect not to proceed with such repair and restoration, in which event Landlord
shall be relieved of its obligation to make such repairs or restoration and this Lease shall terminate as of the date that is 75
days after the later of: (i) discovery of such damage or destruction, or (ii) the date all required Hazardous Materials Clearances
are obtained, but Landlord shall retain any Rent paid and the right to any Rent payable by Tenant prior to such election by Landlord
or Tenant.

 

Tenant, at its expense,
shall promptly perform, subject to delays arising from the collection of insurance proceeds, from Force Majeure (as defined in
Section 34) events or to obtain Hazardous Material Clearances, all repairs or restoration to the Premises not required to
be done by Landlord and shall promptly re-enter the Premises and commence doing business in accordance with this Lease. Notwithstanding
the foregoing, Landlord may terminate this Lease if the Premises are damaged during the last year of the Term and Landlord reasonably
estimates that it will take more than 2 months to repair such damage, or if insurance proceeds are not available for such restoration.
Rent shall be abated from the date all required Hazardous Material Clearances are obtained until the Premises are repaired and
restored, in the proportion which the area of the Premises, if any, which is not usable by Tenant bears to the total area of the
Premises, unless Landlord provides Tenant with other space during the period of repair that is suitable for the temporary conduct
of Tenant’s business. Such abatement shall be the sole remedy of Tenant, and except as provided in this Section 18,
Tenant waives any right to terminate this Lease by reason of damage or casualty loss.

 

The provisions of this
Lease, including this Section 18, constitute an express agreement between Landlord and Tenant with respect to any and all
damage to, or destruction of, all or any part of the Premises, or any other portion of the Project, and any statute or regulation
which is now or may hereafter be in effect shall have no application to this Lease or any damage or destruction to all or any part
of the Premises or any other portion of the Project, the parties hereto expressly agreeing that this Section 18 sets forth
their entire understanding and agreement with respect to such matters.

 

19.       Condemnation.
if the whole or any material part of the Premises or the Project is taken for any public or quasi-public use under governmental
law, ordinance, or regulation, or by right of eminent domain, or by private purchase in lieu thereof (a “Taking”
or “Taken”), and the Taking would in Landlord’s reasonable judgment either prevent or materially interfere
with Tenant’s use of the Premises or materially interfere with or impair Landlord’s ownership or operation of the Project,
then upon written notice by Landlord this Lease shall terminate and Rent shall be apportioned as of said date. If part of the Premises
shall be Taken, and this Lease is not terminated as provided above, Landlord shall promptly restore the Premises and the Project
as nearly as is commercially reasonable under the circumstances to their condition prior to such partial Taking and the rentable
square footage of the Building, the rentable square footage of the Premises, Tenant’s Share of Operating Expenses and the
Rent payable hereunder during the unexpired Term shall be reduced to such extent as may be fair and reasonable under the circumstances.
Upon any such Taking, Landlord shall be entitled to receive the entire price or award from any such Taking without any payment
to Tenant, and Tenant hereby assigns to Landlord Tenant’s interest, if any, in such award. Tenant shall have the right, to
the extent that same shall not diminish Landlord’s award, to make a separate claim against the condemning authority (but
not Landlord) for such compensation as may be separately awarded or recoverable by Tenant for moving expenses and damage to Tenant’s
trade fixtures, if a separate award for such items is made to Tenant. Tenant hereby waives any and all rights it might otherwise
have pursuant to any provision of state law to terminate this Lease upon a partial Taking of the Premises or the Project.

 

20.       Events
of Default. Each of the following events shall be a default (“Default”) by Tenant
under this Lease:

 

(a)       Payment
Defaults. Tenant shall fail to pay any installment of Rent or any other payment hereunder when
due; provided, however, that Landlord will give Tenant notice and an opportunity to cure any failure to pay Rent
within 3 days of any such notice not more than once in any 12 month period and Tenant agrees that such notice shall be in lieu
of and not in addition to, or shall be deemed to be, any notice required by law.

 

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(b)       Insurance.
Any insurance required to be maintained by Tenant pursuant to this Lease shall be canceled or terminated or shall expire or shall
be reduced or materially changed, or Landlord shall receive a notice of nonrenewal of any such insurance and Tenant shall fail
to obtain replacement insurance at least 20 days before the expiration of the current coverage.

 

(c)       Abandonment.
Tenant shall abandon the Premises without (i) the release of the Premises of all Hazardous Materials Clearances and free of any
residual impact from the Tenant HazMat Operations, and (ii) complying with the provisions of Section 28.

 

(d)       Improper
Transfer. Tenant shall assign, sublease or otherwise transfer or attempt to transfer all or
any portion of Tenant’s interest in this Lease or the Premises except as expressly permitted herein, or Tenant’s interest
in this Lease shall be attached, executed upon, or otherwise judicially seized and such action is not released within 90 days of
the action.

 

(e)       Liens.
Tenant shall fail to discharge or otherwise obtain the release of any lien placed upon the Premises in violation of this Lease
within 10 days after notice that any such lien is filed against the Premises.

 

(f)       Insolvency
Events. Tenant or any guarantor or surety of Tenant’s obligations hereunder shall: (A)
make a general assignment for the benefit of creditors; (B) commence any case, proceeding or other action seeking to have an order
for relief entered on its behalf as a debtor or to adjudicate it a bankrupt or insolvent, or seeking reorganization, arrangement,
adjustment, liquidation, dissolution or composition of it or its debts or seeking appointment of a receiver, trustee, custodian
or other similar official for it or for all or any substantial part of its property (collectively a “Proceeding for Relief”);
(C) become the subject of any Proceeding for Relief, voluntary or involuntary; or (D) die or suffer a legal disability (if Tenant,
guarantor, or surety is an individual) or be dissolved or otherwise fail to maintain its legal existence (if Tenant, guarantor
or surety is a corporation, partnership or other entity).

 

(g)       Estoppel
Certificate or Subordination Agreement. Tenant fails to execute any document required from
Tenant under Sections 23 or 27 within 7 days after a second notice requesting such document

 

(h)       Financial
Information. Tenant fails to provide to Landlord the financial information specified in Section
41(c) within the time periods provided therein.

 

(i)       Other
Defaults. Tenant shall fail to comply with any provision of this Lease other than those specifically
referred to in this Section 20, and, except as otherwise expressly provided herein, such failure shall continue for a period
of 15 days after written notice thereof from Landlord to Tenant.

 

Any notice given under Section 20(i)
hereof shall: (i) specify the alleged default, (ii) demand that Tenant cure such default, (iii) be in lieu of, and not in addition
to, or shall be deemed to be, any notice required under any provision of applicable law, and (iv) not be deemed a forfeiture or
a termination of this Lease unless Landlord elects otherwise in such notice; provided that if the nature of Tenant’s default
pursuant to Section 20(i) is such that it cannot be cured by the payment of money and reasonably requires more than 15 days
to cure, then Tenant shall not be deemed to be in default if Tenant commences such cure within said 15 day period and thereafter
diligently prosecutes the same to completion’ provided, however, that such cure shall be completed no later
than 60 days from the date of Landlord’s notice.

 

21.       Landlord’s
Remedies.

 

(a)       Interest.
Upon a Default by Tenant hereunder, Landlord may, without waiving or releasing any obligation of Tenant hereunder, make such payment
or perform such act. Ail sums so paid or incurred by Landlord, together with interest thereon, from the date such sums were paid
or incurred, at the annual rate equal to 12% per annum or the highest rate permitted by law (“Default Rate”),
whichever is less, shall be payable to Landlord on demand as Additional Rent. Nothing herein shall be construed to create or impose
a duty on Landlord to mitigate any damages resulting from Tenant’s Default hereunder.

 

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(b)       Late
Payment Rent. Late payment by Tenant to Landlord of Rent and other sums due will cause Landlord to incur costs not contemplated
by this Lease, the exact amount of which will be extremely difficult and impracticable to ascertain. Such costs include, but are
not limited to, processing and accounting charges and late charges which may be imposed on Landlord under any Mortgage covering
the Premises. Therefore, if any installment of Rent due from Tenant is not received by Landlord within 5 days after the date such
payment is due, Tenant shall pay to Landlord an additional sum of 6% of the overdue Rent as a late charge (provided that Tenant
shall not be required to pay such late charge upon the first occurrence of a late payment by Tenant of Rent). The parties agree
that this late charge represents a fair and reasonable estimate of the costs Landlord will incur by reason of late payment by Tenant.
In addition to the late charge, Rent not paid when due shall bear interest at the Default Rate from the 5th day after the date
due until paid.

 

(c)       Re-Entry.
Landlord shall have the right, immediately or at any time thereafter, without further notice to Tenant (unless otherwise provided
herein), to enter the Premises, without terminating this Lease or being guilty of trespass, and do any and all acts as Landlord
may deem necessary, proper or convenient to cure such default, for the account and at the expense of Tenant, any notice to quit
or notice of Landlord’s intention to re-enter being hereby expressly waived, and Tenant agrees to pay to Landlord as Additional
Rent all damage and/or expense incurred by Landlord in so doing, including interest at the Default Rate, from the due date until
the date payment is received by Landlord.

 

(d)       Termination.
Landlord shall have the right to terminate this Lease and Tenant’s right to possession of the Premises and, with or without
legal process, take possession of the Premises and remove Tenant, any occupant and any property therefrom, using such force as
may be necessary, without being guilty of trespass and without relinquishing any rights of Landlord against Tenant, any notice
to quit, or notice of Landlord’s intention to re-enter being hereby expressly waived. Landlord shall be entitled to recover
damages from Tenant all amounts covenanted to be paid during the remainder of the Term (except for the period of any holdover by
Tenant, in which case the monthly rental rate stated at Section 8 herein shall apply), which amounts may be accelerated
by Landlord at its option, together with (i) all expenses of any proceedings (including, but not limited to, the expenses set forth
in Section 22(f) below) which may be necessary in order for Landlord to recover possession of the Premises, (ii) the expenses
of the re-renting of the Premises (including, but not limited to, any commissions paid to any real estate agent, advertising expense
and the costs of such alterations, repairs, replacements or modifications that Landlord, in its sole judgment, considers advisable
and necessary for the purpose of re-renting), and (iii) interest computed at the Default Rate from the due date until paid.
provided, however that there shall be credited against the amount of such damages all amounts received by Landlord
from such re-renting of the Premises, with any overage being refunded to Tenant. Landlord shall in no event be liable in any way
whatsoever for failure to re-rent the Premises or, in the event that the Premises are re-rented, for failure to collect the rent
thereof under such re-renting and Tenant expressly waives any duty of the Landlord to mitigate damages. No act or thing done by
Landlord shall be deemed to be an acceptance of a surrender of the Premises, unless Landlord shalt execute a written agreement
of surrender with Tenant. Tenant’s liability hereunder shall not be terminated by the execution of a new lease of the Premises
by Landlord, unless that new lease expressly so states. In the event Landlord does not exercise its option to accelerate the payment
of amounts owed as provided hereinabove, then Tenant agrees to pay to Landlord, upon demand, the amount of damages herein provided
after the amount of such damages for any month shall have been ascertained; provided, however, that any expenses
incurred by Landlord shall be deemed to be a part of the damages for the month in which they were incurred. Separate actions may
be maintained each month or at other times by Landlord against Tenant to recover the damages then due, without waiting until the
end of the term of this Lease to determine the aggregate amount of such damages. Tenant hereby expressly waives any and all rights
of redemption granted by or under any present or future laws in the event of Tenant being evicted or being dispossessed for any
cause, or in the event of Landlord obtaining possession of the Premises by reason of the violation by Tenant of any of the covenants
and conditions of this Lease.

 

(e)       Lien
for Rent. Upon any Default by Tenant in the payment of Rent or other amounts owed hereunder, Landlord shall have a lien upon
the property of Tenant in the Premises for the amount of such unpaid amounts, and Tenant hereby specifically waives any and all
exemptions allowed by law. In such event of Default, Tenant shall not remove any of Tenant’s property from the Premises except
with the prior written consent of Landlord, and Landlord shall have the right and privilege, at its option, to take possession
of all Tenant’s property in the Premises, to store the same on the Premises, or to remove it and store it in such place as
may be selected by Landlord, at Tenant’s risk and expense. If Tenant fails to redeem the personal property so seized, by
payment of

 

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whatever sum may be due Landlord hereunder
(including all storage costs), Landlord shall have the right, after twenty (20) days written notice to Tenant of its intention
to do so, to sell such personal property so seized at public or private sale and upon such terms and conditions as may appear advantageous
to Landlord, and after the payment of all proper charges incident to such sale, apply the proceeds thereof to the payment of any
balance due to Landlord on account of rent or other obligations of Tenant pursuant to this Lease. In the event there shall then
remain in the hands of Landlord any balance realized from the sale of said personal property, the same shall be paid over to Tenant.
The exercise of the foregoing remedy by Landlord shall not relieve or discharge Tenant from any deficiency owed to Landlord which
Landlord has the right to enforce pursuant to any of the provisions of this Lease. Tenant shall also be liable for all expenses
incident to the foregoing process, including any auctioneer or attorney’s fees or commissions. At Tenant’s request,
Landlord shall subordinate its lien rights as set forth in this paragraph to the lien, operation, and effect of any bona fide third
party equipment financing pursuant to a subordination agreement in form and substance reasonably acceptable to Landlord. Such subordination
shall be limited to specific items of equipment and shall not be in the form of a blanket lien subordination.

 

(f)       Expenses.
Tenant shall pay, as Additional Rent and immediately upon written demand from Landlord, all costs and expenses incurred by Landlord,
including, but not limited to, attorneys’ fees, expert witness fees, paralegal fees, other litigation expenses (such as expenses
for photocopying, electronic legal research, and deposition transcripts), and court costs in connection with or arising out of
any Default by Tenant under this Lease, including, but not limited to, any action or proceeding brought by Landlord to enforce
any obligation of Tenant under this Lease or the right of Landlord in or to the Premises. Such expenses are recoverable at all
levels, including appeals and post-judgment actions or proceedings. The giving of a notice of Default by Landlord shall constitute
part of an action or proceeding under this Lease, entitling Landlord to reimbursement of such fees and expenses, even if an action
or proceeding is not commenced in a court of law and regardless of whether the Default is cured.

 

(g)       Other
Remedies. Upon a Default by Tenant hereunder and in addition to any other remedy available
to Landlord under this Lease or otherwise, Landlord shall be entitled to recover damages from Tenant the amount of the then unamortized
Rental Abatement. In addition to the remedies set forth in this Section 21, Landlord, at its option, without further notice
or demand to Tenant, shall have all other rights and remedies provided at law or in equity.

 

22.       Assignment
and Subletting.

 

(a)       General
Prohibition. Without Landlord’s prior written consent subject to and on the conditions
described in this Section 22, Tenant shall not, directly or indirectly, voluntarily or by operation of law, assign this
Lease or sublease the Premises or any part thereof or mortgage, pledge, or hypothecate its leasehold interest or grant any concession
or license within the Premises, and any attempt to do any of the foregoing shall be void and of no effect. If Tenant is a corporation,
partnership or limited liability company, the shares or other ownership interests thereof which are not actively traded upon a
stock exchange or in the over-the-counter market, a transfer or series of transfers whereby 49% or more of the issued and outstanding
shares or other ownership interests of such corporation are, or voting control is, transferred (but excepting transfers upon deaths
of individual owners) from a person or persons or entity or entities which were owners thereof at time of execution of this Lease
to persons or entities who were not owners of shares or other ownership interests of the corporation, partnership or limited liability
company at time of execution of this Lease, shall be deemed an assignment of this Lease requiring the consent of Landlord as provided
in this Section 22. Notwithstanding the foregoing, any public offering of shares or other ownership interest in Tenant shall
not be deemed an assignment.

 

(b)       Permitted
Transfers. If Tenant desires to assign, sublease, hypothecate or otherwise transfer this Lease or sublet the Premises other
than pursuant to a Permitted Assignment (as defined below), then at least 10 days, but not more than 45 days, before the date Tenant
desires the assignment or sublease to be effective (“Assignment Date”), Tenant shall give Landlord a notice
(“Assignment Notice”) containing such information about the proposed assignee or sublessee, including the proposed
use of the Premises and any Hazardous Materials proposed to be used, stored handled, treated, generated in or released or disposed
of from the Premises, the Assignment Date, any relationship between Tenant and the proposed assignee or sublessee, and all material
terms and conditions of the proposed assignment or sublease, including a copy of any proposed assignment or sublease in its final
form, and such other information as Landlord may deem reasonably necessary or appropriate to its consideration whether to grant
its consent. Landlord may, by giving written notice to Tenant within 10 days after receipt of the Assignment

 

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Notice: (i) grant such consent, or (ii) reasonably
refuse such consent (provided that Landlord shall further have the right to review and approve or reasonably disapprove the proposed
form of sublease prior to the effective date of any such subletting). No failure of Landlord to deliver a timely notice in response
to the Assignment Notice shall be deemed to be Landlord’s consent to the proposed assignment, sublease or other transfer.
Tenant shall pay to Landlord a fee equal to $1,500 in connection with its consideration of any Assignment Notice and/or its preparation
or review of any consent documents. Notwithstanding the foregoing, Landlord’s consent to an assignment of this Lease or a
subletting of any portion of the Premises to any entity controlling, controlled by, or under common control with Tenant (a “Permitted
Assignment”) shall not be required, provided that Landlord shall have the right to reasonably approve the form of any
such sublease or assignment.

 

Among other reasons, it
shall be reasonable for Landlord to withhold its consent in any of these instances: (i) the proposed assignee or sublessee is engaged
in areas of scientific research or other business concerns that are controversial or its proposed use of the Premises will violate
any applicable Legal Requirement, (ii) the proposed assignee or transferee lacks the creditworthiness to support the financial
obligations it would incur under the proposed assignment or sublease, taking into consideration Tenant’s continued liability
under this Lease, (iii) the use of the Premises by the proposed assignee or sublessee would require increased services by Landlord,
(iv) Landlord has received from any other landlord to the proposed assignee or sublessee a negative report concerning such other
landlord’s experience with the proposed assignee or sublessee, (v) Landlord has experienced previous defaults by or is in
litigation with the proposed assignee or sublessee, (vi) the proposed assignment will create a vacancy elsewhere in the Project,
or (vii) the assignment or sublease is prohibited by Landlord’s lender.

 

Notwithstanding the foregoing,
Tenant shall have the right to assign this Lease, upon 10 days prior written notice to Landlord but without obtaining Landlord’s
prior written consent, to a corporation or other entity that is a successor-in-interest to Tenant, by way of merger, consolidation,
or corporate reorganization, or by the purchase of all or substantially all of the assets or the ownership interests of Tenant
provided that (i) such merger or consolidation, or such acquisition or assumption, as the case may be, is for a good business purpose
and not principally for the purpose of transferring this Lease, and (ii) the net worth (as determined in accordance with generally
accepted accounting principles (“GAAP”)) of the assignee is not less than the net worth (as determined in accordance
with GAAP) of Tenant as of the Commencement Date, and (iii) such assignee shall agree in writing to assume all of the terms, covenants,
and conditions of this Lease arising after the effective date of the assignment (a “Permitted Assignment”).

 

(c)         Additional
Conditions. As a condition to any such assignment or subletting, whether or not Landlord’s
consent is required, Landlord may require:

 

(i)       that
any assignee or subtenant agree, in writing at the time of such assignment or subletting, that if Landlord gives such party notice
that Tenant is in default under this Lease, such party shall thereafter make all payments otherwise due Tenant directly to Landlord,
which payments will be received by Landlord without any liability except to credit such payment against those due under this Lease,
and any such third party shall agree to attorn to Landlord or its successors and assigns should this Lease be terminated for any
reason; provided, however, in no event shall Landlord or its successors or assigns be obligated to accept such attornment;
and

 

(ii)       A
list of Hazardous Materials, certified by the proposed assignee or sublessee to be true and correct, which the proposed assignee
or sublessee intends to use, store, handle, treat, generate in or release or dispose of from the Premises, together with copies
of all documents relating to such use, storage, handling, treatment, generation, release or disposal of Hazardous Materials by
the proposed assignee or subtenant in the Premises or on the Project, prior to the proposed assignment or subletting, including,
without limitation: permits; approvals; reports and correspondence; storage and management plans; plans relating to the installation
of any storage tanks to be installed in or under the Project (provided, said installation of tanks shall only be permitted
after Landlord has given its written consent to do so, which consent may be withheld in Landlord’s sole and absolute discretion);
and all closure plans or any other documents required by any and all federal, state and local Governmental Authorities for any
storage tanks installed in, on or under the Project for the closure of any such tanks. Neither Tenant nor any such proposed assignee
or subtenant is required, however, to provide Landlord with any portion(s) of the such

 

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documents containing information of
a proprietary nature which, in and of themselves, do not contain a reference to any Hazardous Materials or hazardous activities.

 

(d)       No
Release of Tenant, Sharing of Excess Rents. Notwithstanding any assignment or subletting, Tenant
and any guarantor or surety of Tenant’s obligations under this Lease shall at all times remain fully and primarily responsible
and liable for the payment of Rent and for compliance with all of Tenants other obligations under this Lease. If the Rent due and
payable by a sublessee or assignee (or a combination of the rental payable under such sublease or assignment plus any bonus or
other consideration therefor or incident thereto in any form, excluding any payment in respect of the business conducted at the
Premises) exceeds the sum of the Rent and all other sums payable under this Lease (excluding however, any Rent payable under this
Section) and actual and reasonable brokerage fees, legal costs and any design or construction fees directly related to and required
pursuant to the terms of any such sublease) (“Excess Rent”), then Tenant shall be bound and obligated to pay
Landlord as Additional Rent hereunder 50% of such Excess Rent within 10 days following receipt thereof by Tenant. if Tenant shall
sublet the Premises or any part thereof, Tenant hereby immediately and irrevocably assigns to Landlord, as security for Tenant’s
obligations under this Lease, ail rent from any such subletting, and Landlord as assignee, or a receiver for Tenant appointed on
Landlord’s application, may collect such rent and apply it toward Tenants obligations under this Lease; except that, until
the occurrence of a Default, Tenant shall have the right to collect such rent.

 

(e)       No
Waiver. The consent by Landlord to an assignment or subletting shall not relieve Tenant or
any assignees of this Lease or any sublessees of the Premises from obtaining the consent of Landlord to any further assignment
or subletting nor shall it release Tenant or any assignee or sublessee of Tenant from full and primary liability under this Lease.
The acceptance of Rent hereunder, or the acceptance of performance of any other term, covenant, or condition thereof, from any
other person or entity shall not be deemed to be a waiver of any of the provisions of this Lease or a consent to any subletting,
assignment or other transfer of the Premises.

 

(f)       Prior
Conduct of Proposed Transferee. Notwithstanding any other provision of this Section 22,
if (i) the proposed assignee or sublessee of Tenant has been required by any prior landlord, lender or Governmental Authority to
take remedial action in connection with Hazardous Materials contaminating a property, where the contamination resulted from such
party’s action or use of the property in question, (ii) the proposed assignee or sublessee is subject to an enforcement order
issued by any Governmental Authority in connection with the use, storage, handling, treatment, generation, release or disposal
of Hazardous Materials (including, without limitation, any order related to the failure to make a required reporting to any Governmental
Authority), or (iii) because of the existence of a pre-existing environmental condition in the vicinity of or underlying the Project,
the risk that Landlord would be targeted as a responsible party in connection with the remediation of such pre-existing environmental
condition would be materially increased or exacerbated by the proposed use of Hazardous Materials by such proposed assignee or
sublessee, Landlord shall have the absolute right to refuse to consent to any assignment or subletting to any such party.

 

23.       Estoppel
Certificate. Tenant shall, within 10 business days of written notice from Landlord, execute, acknowledge and deliver a statement
in writing in any form reasonably requested by a proposed lender or purchaser, (I) certifying that this Lease is unmodified and
in full force and effect (or, if modified, stating the nature of such modification and certifying that this Lease as so modified
is in full force and effect) and the dates to which the rental and other charges are paid in advance, if any, (ii) acknowledging
that there are not any uncured defaults on the part of Landlord hereunder, or specifying such defaults if any are claimed, and
(iii) setting forth such further information with respect to the status of this Lease or the Premises as may be requested thereon.
Any such statement may be relied upon by any prospective purchaser or encumbrancer of all or any portion of the real property of
which the Premises are a part. Tenant’s failure to deliver such statement within such time shall, at the option of Landlord,
be conclusive upon Tenant that this Lease is in full force and effect and without modification except as may be represented by
Landlord in any certificate prepared by Landlord and delivered to Tenant for execution.

 

24.       Quiet
Enjoyment. So long as Tenant shall perform all of the covenants and agreements herein required
to be performed by Tenant, Tenant shall, subject to the terms of this Lease, at all times during the Term, have peaceful and quiet
enjoyment of the Premises against any person claiming by, through or under Landlord.

 

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25.       Prorations.
All prorations required or permitted to be made hereunder shall be made on the basis of a 360 day year and 30 day months.

 

26.       Rules
and Regulations. Tenant shall, at all times during the Term and any extension thereof, comply
with all reasonable rules and regulations at any time or from time to time established by Landlord covering use of the Premises
and the Project. The current rules and regulations are attached hereto as Exhibit E. If there is any conflict between said rules
and regulations and other provisions of this Lease, the terms and provisions of this Lease shall control. Landlord shall not have
any liability or obligation for the breach of any rules or regulations by other tenants in the Project and shall not enforce such
rules and regulations in a discriminatory manner.

 

27.       Subordination.
This Lease and Tenant’s interest and rights hereunder are hereby made and shall be subject and subordinate at all times to
the lien of any Mortgage now existing or hereafter created on or against the Project or the Premises, and all amendments, restatements,
renewals, modifications, consolidations, refinancing, assignments and extensions thereof, without the necessity of any further
instrument or act on the part of Tenant; provided however that so long as there is no Default hereunder, Tenant’s
right to possession of the Premises shall not be disturbed by the Holder of any such Mortgage. Tenant agrees, at the election of
the Holder of any such Mortgage, to attorn to any such Holder. Tenant agrees upon demand to execute, acknowledge and deliver such
instruments, confirming such subordination, and such instruments of attainment as shall be requested by any such Holder, provided
any such instruments contain appropriate non-disturbance provisions assuring Tenant’s quiet enjoyment of the Premises as
set forth in Section 24 hereof. Notwithstanding the foregoing, any such Holder may at any time subordinate its Mortgage
to this Lease, without Tenant’s consent, by notice in writing to Tenant, and thereupon this Lease shall be deemed prior to
such Mortgage without regard to their respective dates of execution, delivery or recording and in that event such Holder shall
have the same rights with respect to this Lease as though this Lease had been executed prior to the execution, delivery and recording
of such Mortgage and had been assigned to such Holder. On Tenant’s written request, Landlord shall use its commercially reasonable
efforts (but with no obligation to pay any out-of-pocket fees or sums) to obtain from any Holder of a first lien Mortgage at any
time during the Term covering any or all of the Project or the Premises a non-disturbance agreement on Holder’s standard
form in favor of Tenant assuring Tenant’s quiet enjoyment of the Premises as set forth in Section 24 hereof. The term
“Mortgage” whenever used in this Lease shall be deemed to include deeds of trust, security assignments and any
other encumbrances, and any reference to the “Holder” of a Mortgage shall be deemed to include the beneficiary
under a deed of trust.

 

28.       Surrender.
Upon the expiration of the Term or earlier termination of Tenant’s right of possession. Tenant shall surrender the Premises
to Landlord in the same condition as received, subject to any Alterations or Installations permitted by Landlord to remain in the
Premises and subject to the provisions of Section 12. Such surrendered Premises shall be free of Hazardous Materials brought
upon, kept, used, stored, handled, treated, generated in, or released or disposed of from, the Premises by Tenant or any Tenant
Party (collectively, “Tenant HazMat Operations”) and released of all Hazardous Materials Clearances, broom clean,
ordinary wear and tear and casualty loss and condemnation covered by Sections 18 and 19 excepted. At least 3 months
prior to the surrender of the Premises, Tenant shall deliver to Landlord a narrative description of the actions proposed (or required
by any Governmental Authority) to be taken by Tenant in order to surrender the Premises (including any installations permitted
by Landlord to remain in the Premises) at the expiration or earlier termination of the Term, free from any residual impact from
the Tenant HazMat Operations and otherwise released for unrestricted use and occupancy (“Surrender Plan”). Such
Surrender Plan shall be accompanied by a current listing of (i) all Hazardous Materials licenses and permits held by or on behalf
of any Tenant Party with respect to the Premises, and (ii) all Hazardous Materials used, stored, handled, treated, generated, released
or disposed of from the Premises, and shall be subject to the review and approval of Landlord’s environmental consultant.
In connection with the review and approval of the Surrender Plan, upon the request of Landlord, Tenant shall deliver to Landlord
or its consultant such additional non-proprietary information concerning Tenant HazMat Operations as Landlord shall request. On
or before such surrender, Tenant shall deliver to Landlord evidence that the approved Surrender Plan shall have been satisfactorily
completed and Landlord shall have the right, subject to reimbursement at Tenant’s expense as set forth below, to cause Landlord’s
environmental consultant to inspect the Premises and perform such additional procedures as may be deemed reasonably necessary to
confirm that the Premises are, as of the effective date of such surrender or early termination of this Lease, free from any residual
impact from Tenant HazMat Operations. Tenant shall reimburse Landlord, as Additional Rent, for the actual out-of pocket expense
incurred by Landlord for Landlord’s environmental consultant to review and approve the Surrender Plan and to visit the Premises
and verify satisfactory

 

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completion of the same, which cost shall not
exceed $5,000. Landlord shall have the unrestricted right to deliver such Surrender Plan and any report by Landlord’s environmental
consultant with respect to the surrender of the Premises to third parties.

 

If Tenant shall fail to
prepare or submit a Surrender Plan approved by Landlord, or if Tenant shall fail to complete the approved Surrender Plan, or if
such Surrender Plan, whether or not approved by Landlord, shall fail to adequately address any residual effect of Tenant HazMat
Operations in, on or about the Premises, Landlord shall have the right to take such actions as Landlord may deem reasonable or
appropriate to assure that the Premises and the Project are surrendered free from any residual impact from Tenant HazMat Operations,
the cost of which actions shall be reimbursed by Tenant as Additional Rent, without regard to the limitation set forth in the first
paragraph of this Section 28.

 

Tenant shall immediately
return to Landlord all keys and/or access cards to parking, the Project, restrooms or all or any portion of the Premises furnished
to or otherwise procured by Tenant. if any such access card or key is lost, Tenant shall pay to Landlord, at Landlord’s election,
either the cost of replacing such lost access card or key or the cost of reprogramming the access security system in which such
access card was used or changing the lock or locks opened by such lost key. Any Tenant’s Property, Alterations and property
not so removed by Tenant as permitted or required herein shall be deemed abandoned and may be stored, removed, and disposed of
by Landlord at Tenant’s expense, and Tenant waives all claims against Landlord for any damages resulting from Landlord’s
retention and/or disposition of such property. All obligations of Tenant hereunder not fully performed as of the termination of
the Term, including the obligations of Tenant under Section 30 hereof, shall survive the expiration or earlier termination
of the Term, including, without limitation, indemnity obligations, payment obligations with respect to Rent and obligations concerning
the condition and repair of the Premises.

 

29.       Waiver
of Jury Trial. TENANT AND LANDLORD WAIVE ANY RIGHT TO TRIAL BY JURY OR TO HAVE A JURY PARTICIPATE
IN RESOLVING ANY DISPUTE, WHETHER SOUNDING IN CONTRACT, TORT, OR OTHERWISE, BETWEEN LANDLORD AND TENANT ARISING OUT OF THIS LEASE
OR ANY OTHER INSTRUMENT, DOCUMENT, OR AGREEMENT EXECUTED OR DELIVERED IN CONNECTION HEREWITH OR THE TRANSACTIONS RELATED HERETO.

 

30.       Environmental
Requirements.

 

(a)       Prohibition/Compliance/Indemnity.
Tenant shall not cause or permit any Hazardous Materials (as hereinafter defined) to be brought upon, kept, used, stored, handled,
treated, generated in or about, or released or disposed of from, the Premises or the Project in violation of applicable Environmental
Requirements (as hereinafter defined) by Tenant or any Tenant Party. If Tenant breaches the obligation stated in the preceding
sentence, or if the presence of Hazardous Materials in the Premises during the Term or any holding over results in contamination
of the Premises, the Project or any adjacent property or if contamination of the Premises, the Project or any adjacent property
by Hazardous Materials brought into, kept, used, stored, handled, treated, generated in or about, or released or disposed of from,
the Premises by anyone other than Landlord and Landlord’s employees, agents and contractors otherwise occurs during the Term
or any holding over, Tenant hereby indemnifies and shall defend and hold Landlord, its officers, directors, employees, agents and
contractors harmless from any and all actions (including, without limitation, remedial or enforcement actions of any kind, administrative
or judicial proceedings, and orders or judgments arising out of or resulting therefrom), costs, claims, damages (including, without
limitation, punitive damages and damages based upon diminution in value of the Premises or the Project, or the loss of, or restriction
on, use of the Premises or any portion of the Project), expenses (including, without limitation, attorneys’, consultants’
and experts’ fees, court costs and amounts paid in settlement of any claims or actions), fines, forfeitures or other civil,
administrative or criminal penalties, injunctive or other relief (whether or not based upon personal injury, property damage, or
contamination of, or adverse effects upon, the environment, water tables or natural resources), liabilities or losses (collectively,
“Environmental Claims”) which arise during or after the Term as a result of such contamination, Notwithstanding
anything to the contrary contained in this Section 30 Tenant shall not be responsible for, and the indemnification and hold
harmless obligation set forth in this paragraph shall not apply to, the presence of any Hazardous Materials in the Premises that
migrated from outside of the Premises into the Premises unless the presence of such Hazardous Materials (i) is the result of a
breach by Tenant of any of its obligations under this Lease, or (ii) was caused, contributed to, or exacerbated by Tenant or any
Tenant Party. This indemnification of Landlord by Tenant includes, without limitation, costs incurred in connection with any investigation
of site

 

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conditions or any cleanup, treatment, remedial,
removal, or restoration work required by any federal, state or local Governmental Authority because of Hazardous Materials present
in the air, soil or ground water above, on, or under the Premises. Without limiting the foregoing, if the presence of any Hazardous
Materials on the Premises, the Project or any adjacent property caused or permitted by Tenant or any Tenant Party results in any
contamination of the Premises, the Project or any adjacent property, Tenant shall promptly take all actions at its sole expense
and in accordance with applicable Environmental Requirements as are necessary to return the Premises, the Project or any adjacent
property to the condition existing prior to the time of such contamination, provided that Landlord’s approval of such action
shall first be obtained, which approval shall riot unreasonably be withheld so long as such actions would not potentially have
any material adverse long-term or short-term effect on the Premises or the Project.

 

(b)       Business.
Landlord acknowledges that it is not the intent of this Section 30 to prohibit Tenant from using the Premises for the Permitted
Use. Tenant may operate its business according to prudent industry practices so long as the use or presence of Hazardous Materials
is strictly and properly monitored according to all then applicable Environmental Requirements. As a material inducement to Landlord
to allow Tenant to use Hazardous Materials in connection with its business, Tenant agrees to deliver to Landlord prior to the Commencement
Date a list identifying each type of Hazardous Materials to be brought upon, kept, used, stored, handled, treated, generated on,
or released or disposed of from, the Premises and setting forth any and all governmental approvals or permits required in connection
with the presence, use, storage, handling, treatment, generation, release or disposal of such Hazardous Materials on or from the
Premises (“Hazardous Materials List”). Tenant shall deliver to Landlord an updated Hazardous Materials List
at least once a year and shall also deliver an updated list before any new Hazardous Material is brought onto, kept, used, stored,
handled, treated, generated on, or released or disposed of from, the Premises. Tenant Shall deliver to Landlord true and correct
copies of the following documents (“Haz Mat Documents”) relating to the use, storage, handling, treatment, generation,
release or disposal of Hazardous Materials prior to the Commencement Date, or if unavailable at that time, concurrent with the
receipt from or submission to a Governmental Authority: permits; approvals; reports and correspondence; storage and management
plans, notice of violations of any Legal Requirements; plans relating to the installation of any storage tanks to be installed
in or under the Project (provided, said installation of tanks shall only be permitted after Landlord has given Tenant its written
consent to do so, which consent may be withheld in Landlord’s sole and absolute discretion); all closure plans or any other
documents required by any and all federal, state and local Governmental Authorities for any storage tanks installed in, on or under
the Project for the closure of any such tanks; and a Surrender Plan (to the extent surrender in accordance with Section 26
cannot be accomplished in 3 months). Tenant is not required, however, to provide Landlord with any portion(s) of the Haz Mat Documents
containing information of a proprietary nature which, in and of themselves, do not contain a reference to any Hazardous Materials
or hazardous activities. It is not the intent of this Section to provide Landlord with information which could be detrimental to
Tenant’s business should such information become possessed by Tenant’s competitors.

 

(c)       Tenant
Representation and Warranty. Tenant hereby represents and warrants to Landlord that (I) neither
Tenant nor any of its legal predecessors has been required by any prior landlord, lender or Governmental Authority at any time
to take remedial action in connection with Hazardous Materials contaminating a property which contamination was permitted by Tenant
of such predecessor or resulted from Tenant’s or such predecessor’s action or use of the property in question, and
(ii) Tenant is not subject to any enforcement order issued by any Governmental Authority in connection with the use, storage, handling,
treatment, generation, release or disposal of Hazardous Materials (including, without limitation, any order related to the failure
to make a required reporting to any Governmental Authority). If Landlord determines that this representation and warranty was not
true as of the date of this lease, Landlord shall have the right to terminate this Lease in Landlord’s sole and absolute
discretion.

 

(d)       Testing.
Landlord shall have the right to conduct annual tests of the Premises to determine whether any contamination of the Premises or
the Project has occurred as a result of Tenants use. Tenant shall be required to pay the cost of such annual test of the Premises;
provided, however, that if Tenant conducts its own tests of the Premises using third party contractors and test procedures
acceptable to Landlord which tests are certified to Landlord, Landlord shall accept such tests in lieu of the annual tests to be
paid for by Tenant In addition, at any time, and from time to time, prior to the expiration or earlier termination of the Term,
Landlord shall have the right to conduct appropriate tests of the Premises and the Project to determine if contamination has occurred
as a result of Tenant’s use of the Premises. In connection with such testing, upon the request of Landlord, Tenant shall
deliver to

 

    	 	21	 

     

    

  

Landlord or its consultant such non-proprietary
information concerning the use of Hazardous Materials in or about the Premises by Tenant or any Tenant Party. If contamination
has occurred for which Tenant is liable under this Section 30, Tenant shall pay all costs to conduct such tests. If no such
contamination is found, Landlord shall pay the costs of such tests (which shall not constitute an Operating Expense). Landlord
shall provide Tenant with a copy of all third party, non-confidential reports and tests of the Premises made by or on behalf of
Landlord during the Term without representation or warranty and subject to a confidentiality agreement. Tenant shall, at its sole
cost and expense, promptly and satisfactorily remediate any environmental conditions identified by such testing in accordance with
all Environmental Requirements. Landlord’s receipt of or satisfaction with any environmental assessment in no way waives
any rights which Landlord may have against Tenant.

 

(e)         Underground
Tanks. If underground or other storage tanks storing Hazardous Materials located on the Premises
or the Project are used by Tenant or are hereafter placed on the Premises or the Project by Tenant, Tenant shall install, use,
monitor, operate, maintain, upgrade and manage such storage tanks, maintain appropriate records, obtain and maintain appropriate
insurance, implement reporting procedures, property close any underground storage tanks, and take or cause to be taken all other
actions necessary or required under applicable state and federal Legal Requirements, as such now exists or may hereafter be adopted
or amended in connection with the installation, use, maintenance, management, operation, upgrading and closure of such storage
tanks.

 

(f)         Control
Areas. Tenant shall be allowed to utilize up to its pro rata share of the Hazardous Materials inventory within any control
area or zone (located within the Premises), as designated from time to time by the applicable building code or other Legal Requirement,
for Hazardous Materials use or storage. As used in the preceding sentence, Tenant’s pro rata share of any control area or
zone located within the Premises shall be determined based on the rentable square footage that Tenant leases within the applicable
control area or zone. For purposes of example only, if a control area or zone contains 10,000 rentable square feet and 2,000 rentable
square feet of a tenants premises are located within such control area or zone (while such premises as a whole contains 5,000 rentable
square feet), the applicable tenants pro rata share of such control area or zone would be 20%.

 

(g)         Tenant’s
Obligations. Tenant’s obligations under this Section 30 shall survive the expiration
or earlier termination of this Lease for the applicable statute of limitations period under federal, state, or local Legal Requirement.
During any period of time after the expiration or earlier termination of this Lease required by Tenant or Landlord to complete
the removal from the Premises of any Hazardous Materials (including, without limitation, the release and termination of any licenses
or permits restricting the use of the Premises and the completion of the approved Surrender Plan), Tenant shall continue to pay
the full Rent in accordance with this Lease for any portion of the Premises not relet by Landlord in Landlord’s sole discretion,
which Rent shall be prorated daily.

 

(h)         Definitions.
As used herein, (i) the term “Environmental Requirements” means all applicable present and future statutes, regulations,
ordinances, rules, codes, judgments, orders or other similar enactments of any Governmental Authority regulating or relating to
health, safety, or environmental conditions on, under, or about the Premises or the Project, or the environment, including without
limitation, the following: the Comprehensive Environmental Response, Compensation and Liability Act; the Resource Conservation
and Recovery Act; and all state and local counterparts thereto, and any regulations or policies promulgated or issued thereunder,
and (ii) the term “Hazardous Materials” means and includes any substance, material, waste, pollutant, or contaminant
listed or defined as hazardous or toxic, or regulated by reason of its impact or potential impact on humans, animals and/or the
environment under any Environmental Requirements, asbestos and petroleum, including crude oil or any fraction thereof, natural
gas liquids, liquefied natural gas, or synthetic gas usable for fuel (or mixtures of natural gas and such synthetic gas). As defined
in Environmental Requirements, Tenant is and shall be deemed to be the “operator” of Tenant’s “facility”
and the “owner” of all Hazardous Materials brought on the Premises by Tenant or any Tenant Party, and the wastes,
by-products, or residues generated, resulting, or produced therefrom.

 

(i)         Asbestos.

 

(i)       Notification
of Asbestos. Landlord hereby notifies Tenant of the presence of asbestos-containing materials (“ACMs”) and/or
presumed asbestos-containing materials (“PACMs”) within or about the Premises in the locations identified in
Exhibit G.

 

    	 	22	 

     

    

  

(ii)       Tenant
Acknowledgement. Tenant hereby acknowledges receipt of the notification in paragraph (I) of this Section 30 and understands
that the purpose of such notification is to make Tenant, and any agents, employees, and contractors of Tenant, aware of the presence
of ACMs and/or PACMs within or about the Building to avoid or minimize any damage to or disturbance of such ACMs and/or PACMs.

 

___________

Tenant’s Initials

 

(iii)       Acknowledgement
from Contractors/Employees. Tenant shall give Landlord at least 14 days’ prior written notice before conducting, authorizing,
or permitting any of the activities listed below within or about the Premises, and before soliciting bids from any person to perform
such services. Such notice shall identify or describe the proposed scope, location, date, and time of such activities and the name,
address and telephone number of each person who may be conducting such activities. Thereafter, Tenant shall grant Landlord reasonable
access to the Premises to determine whether any ACMs or PACMs will be disturbed in connection with such activities. Tenant shall
not solicit bids from any person for the performance of such activities without Landlord’s prior written approval. Upon Landlord’s
request, Tenant shall deliver to Landlord a copy of a signed acknowledgement from any contractor, agent, or employee of Tenant
acknowledging receipt of information describing the presence of ACMs and/or PACMs within or about the Premises in the locations
identified in Exhibit G prior to the commencement of such activities. Nothing in this Section 30(i) shall be deemed
to expand Tenant’s rights under the Lease or otherwise to conduct, authorize or permit any such activities.

 

(A)       Removal
of thermal system insulation (“TSI”) and surfacing ACMs and PACMs (i.e., sprayed-on or troweled-on material,
e.g., textured ceiling paint or fireproofing material);

 

(B)       Removal
of ACMs or PACMs that are not TSI or surfacing ACMs or PACMs, or

 

(C)       Repair
and maintenance of operations that are likely to disturb ACMs or PACMs.

 

(j)       Landlord’s
Covenants. Except in the case of an emergency, (A) Landlord shall give Tenant at least 5 business
days’ prior written notice before conducting, authorizing, or permitting any activities that may disturb ACMs or PACMs within
or about the Premises or in that portion of the Common Areas consisting of (x) the lobby entrance serving the Premises, (y) the
corridor located between such lobby entrance and the Premises, and (z) the bank of restrooms closest to the Premises, and (B) any
work that may disturb ACMs or PACMs in or about the Premises shall be conducted between the hours of 6:00 p.m. on Friday and 7:00
a.m. on Monday. Landlord shall comply with the O&M Program (as defined in Exhibit G) in connection with any work undertaken
by Landlord in the Building. In performing any activities that may disturb ACMs or PACMs within or about the Premises or in the
foregoing portions of the Common Areas, Landlord shall comply with all applicable Legal Requirements.

 

31.       Tenant’s
Remedies/Limitation of Liability. Landlord shall not be in default hereunder unless Landlord
fails to perform any of its obligations hereunder within 30 days after written notice from Tenant specifying such failure (unless
such performance will, due to the nature of the obligation, require a period of time in excess of 30 days, then after such period
of time as is reasonably necessary). Upon any default by Landlord, Tenant shall give notice by registered or certified mail to
any Holder of a Mortgage covering the Premises and to any landlord of any lease of property in or on which the Premises are located
and Tenant shall offer such Holder and/or landlord a reasonable opportunity to cure the default, including time to obtain possession
of the Project by power of sale or a judicial action if such should prove necessary to effect a cure; provided Landlord shall have
furnished to Tenant in writing the names and addresses of all such persons who are to receive such notices. All obligations of
Landlord hereunder shall be construed as covenants, not conditions; and, except as may be otherwise expressly provided in this
Lease, Tenant may not terminate this Lease for breach of Landlord’s obligations hereunder.

 

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All obligations of Landlord
under this Lease will be binding upon Landlord only during the period of its ownership of the Premises and not thereafter. The
term “Landlord” in this Lease shall mean only the owner for the time being of the Premises. Upon the transfer
by such owner of its interest in the Premises, such owner shall thereupon be released and discharged from all obligations of Landlord
thereafter accruing, but such obligations shall be binding during the Term upon each new owner for the duration of such owner’s
ownership.

 

32.       Inspection
and Access. Landlord and its agents, representatives, and contractors may enter the Premises at any reasonable time to inspect
the Premises and to make such repairs as may be required or permitted pursuant to this Lease and for any other business purpose.
Landlord and Landlord’s representatives may enter the Premises during business hours on not less than 48 hours advance written
notice (except in the case of emergencies in which case no such notice shall be required and such entry may be at any time) for
the purpose of effecting any such repairs, inspecting the Premises, showing the Premises to prospective purchasers and, during
the fast year of the Term, to prospective tenants or for any other business purpose. Landlord may erect a suitable sign on the
Premises stating the Premises are available to let or that the Project is available for sale. Landlord may grant easements, make
public dedications, designate Common Areas and create restrictions on or about the Premises, provided that no such easement, dedication,
designation or restriction materially, adversely affects Tenant’s use or occupancy of the Premises for the Permitted Use,
At Landlord’s request, Tenant shall execute such instruments as may be necessary for such easements, dedications or restrictions.
Tenant shall at all times, except in the case of emergencies, have the right to escort Landlord or its agents, representatives,
contractors or guests while the same are in the Premises, provided such escort does not materially and adversely affect Landlord’s
access rights hereunder.

 

33.       Security.
Tenant acknowledges and agrees that security devices and services, if any, while intended to deter crime may not in given instances
prevent theft or other criminal acts and that Landlord is not providing any security services with respect to the Premises. Tenant
agrees that Landlord shall not be liable to Tenant for, and Tenant waives any claim against Landlord with respect to, any loss
by theft or any other damage suffered or incurred by Tenant in connection with any unauthorized entry into the Premises or any
other breach of security at the Premises. Tenant shall be solely responsible for the personal safety of Tenant’s officers,
employees, agents, contractors, guests and invitees while any such person is in, on or about the Premises and/or the Project. Tenant
shall at Tenant’s cost obtain insurance coverage to the extent Tenant desires protection against such criminal acts.

 

34.       Force
Majeure. Neither Landlord nor Tenant shall be responsible or liable for delays in the performance
of its obligations hereunder when caused by, related to, or arising out of acts of God, strikes, lockouts, or other labor disputes,
embargoes, quarantines, weather, national, regional, or local disasters, calamities, or catastrophes, inability to obtain labor
or materials (or reasonable substitutes therefor) at reasonable costs or failure of, or inability to obtain, utilities necessary
for performance, governmental restrictions, orders, limitations, regulations, or controls, national emergencies, delay in issuance
or revocation of permits, enemy or hostile governmental action, terrorism, insurrection, riots, civil disturbance or commotion,
fire or other casualty, and other causes or events beyond the reasonable control of Landlord (“Force Majeure”);
provided, however, that in no event shall Force Majeure excuse Tenant or Landlord from performing any monetary obligation
under this Lease.

 

35.       Brokers.
Landlord and Tenant each represents and warrants that it has not dealt with any broker, agent or other person (collectively, “Broker”)
in connection with this transaction and that no Broker brought about this transaction, other than Tenant’s broker, Jones
Lang LaSalle (“JLL”), and Landlord’s broker, Edge Commercial Real Estate (“Edge”).
JLL shall be paid by Landlord pursuant to a separate agreement between Landlord and JLL. Edge shall be paid by Landlord pursuant
to a separate agreement between Landlord and Edge. Landlord and Tenant each hereby agree to indemnify and hold the other harmless
from and against any claims by any Broker, other than JLL and Edge, claiming a commission or other form of compensation by virtue
of having dealt with Tenant or Landlord, as applicable, with regard to this leasing transaction.

 

36.       Limitation
on Landlord’s Liability. NOTWITHSTANDING ANYTHING SET FORTH HEREIN OR IN ANY OTHER AGREEMENT BETWEEN LANDLORD AND TENANT
TO THE CONTRARY: (A) LANDLORD SHALL NOT BE LIABLE TO TENANT OR ANY OTHER PERSON FOR (AND TENANT AND EACH SUCH OTHER PERSON ASSUME
ALL RISK OF) LOSS, DAMAGE OR INJURY, WHETHER ACTUAL OR CONSEQUENTIAL TO: TENANT’S PERSONAL PROPERTY OF EVERY KIND AND DESCRIPTION,
INCLUDING, WITHOUT LIMITATION TRADE FIXTURES, EQUIPMENT, INVENTORY,

 

    	 	24	 

     

    

  

SCIENTIFIC RESEARCH, SCIENTIFIC EXPERIMENTS,
LABORATORY ANIMALS, PRODUCT, SPECIMENS, SAMPLES, AND/OR SCIENTIFIC, BUSINESS, ACCOUNTING AND OTHER RECORDS OF EVERY KIND AND DESCRIPTION
KEPT AT THE PREMISES AND ANY AND ALL INCOME DERIVED OR DERIVABLE THEREFROM; (B) THERE SHALL BE NO PERSONAL RECOURSE TO LANDLORD
FOR ANY ACT OR OCCURRENCE IN, ON OR ABOUT THE PREMISES OR ARISING IN ANY WAY UNDER THIS LEASE OR ANY OTHER AGREEMENT BETWEEN LANDLORD
AND TENANT WITH RESPECT TO THE SUBJECT MATTER HEREOF AND ANY LIABILITY OF LANDLORD HEREUNDER SHALL BE STRICTLY LIMITED SOLELY TO
LANDLORD’S INTEREST IN THE PROJECT OR ANY PROCEEDS FROM SALE OR CONDEMNATION THEREOF AND ANY INSURANCE PROCEEDS PAYABLE IN
RESPECT OF LANDLORD’S INTEREST IN THE PROJECT OR IN CONNECTION WITH ANY SUCH LOSS; AND (C) IN NO EVENT SHALL ANY PERSONAL
LIABILITY BE ASSERTED AGAINST ANY OF LANDLORD’S OFFICERS, DIRECTORS, EMPLOYEES, AGENTS OR CONTRACTORS. UNDER NO CIRCUMSTANCES
SHALL LANDLORD OR ANY OF LANDLORD’S OFFICERS, DIRECTORS, EMPLOYEES, AGENTS OR CONTRACTORS BE LIABLE FOR INJURY TO TENANT’S
BUSINESS OR FOR ANY LOSS OF INCOME OR PROFIT THEREFROM,

 

37.       Severability.
If any clause or provision of this Lease is illegal, invalid or unenforceable under present or future laws, then and in that event,
it is the intention of the parties hereto that the remainder of this Lease shall not be affected thereby. It is also the intention
of the parties to this Lease that in lieu of each clause or provision of this Lease that is illegal, invalid or unenforceable,
there be added, as a part of this Lease, a clause or provision as similar in effect to such illegal, invalid or unenforceable clause
or provision as shall be legal, valid and enforceable. This Lease, including the exhibits attached hereto, constitutes the entire
agreement between Landlord and Tenant pertaining to the subject matter hereof and supersedes all prior agreements, understandings,
letters of intent, negotiations, and discussions, whether oral or written, of the parties, and there are no warranties, representations,
or other agreements, express or implied, made to either party by the other party in connection with the subject matter hereof except
as specifically set forth herein or in the documents delivered pursuant hereto or in connection herewith.

 

38.       Signs;
Exterior Appearance. Tenant shall not, without the prior written consent of Landlord, which
may be granted or withheld in Landlord’s sole discretion: (i) attach any awnings, exterior lights, decorations, balloons,
flags, pennants, banners, painting or other projection to any outside wall of the Project, (ii) use any curtains, blinds, shades
or screens other than Landlord’s standard window coverings, (iii) coat or otherwise sunscreen the interior or exterior of
any windows, (iv) place any bottles, parcels, or other articles on the window sills, (v) place any equipment, furniture or other
items of personal property on any exterior balcony, or (vi) paint, affix or exhibit on any part of the Premises or the Project
any signs, notices, window or door lettering, placards, decorations, or advertising media of any type which can be viewed from
the exterior of the Premises. Interior signs on doors and the directory tablet shall be inscribed, painted or affixed for Tenant
by Landlord at the sole cost and expense of Tenant, and shall be of a size, color and type acceptable to Landlord (it being agreed
that Tenant’s logo is acceptable). Nothing may be placed on the exterior of corridor walls or corridor doors other than Landlord’s
standard lettering and Tenant’s logo on the suite entry sign adjacent to the entrance door to the Premises (no signage shall
be placed on the entrance door). The directory tablet shall be provided exclusively for the display of the name and location of
tenants.

 

39.       Right
to Extend Term. Tenant shall have the right to extend the Term of this Lease upon the following
terms and conditions:

 

(a)       Extension
Right. Tenant shall have the right (“Extension Right”) to extend the term
of this Lease for 5 years (“Extension Term”) on the same terms and conditions as this Lease (other than Base
Rent) by giving Landlord written notice of its election to exercise the Extension Right at least 9 months prior, and no earlier
than 12 months prior, to the expiration of the Base Term of this Lease.

 

(b)       Base
Rent Adjustment. Upon the commencement of the Extension Term, Base Rent shall be payable at
the Market Rate (as defined below). Base Rent shall thereafter be adjusted on each anniversary of the commencement of the Extension
Term by a percentage as determined by Landlord and agreed to by Tenant at the time the Market Rate is determined. As used herein,
“Market Rate” shall mean the then market rental rate as determined by Landlord and agreed to by Tenant. If,
on or before the date that is 120 days prior to the expiration of

 

    	 	25	 

     

    

  

the Base Term of this Lease, Tenant has not
agreed with Landlord’s determination of the Market Rate and the rent escalations during such subsequent Extension Term after
negotiating in good faith, Tenant may by written notice to Landlord not later than 120 days prior to the expiration of the Base
Term of this Lease, elect arbitration as described in this Section 39 below. If Tenant does not elect such arbitration,
Tenant shall be deemed to have waived any right to extend the Term of this Lease and the Extension Right shall terminate.

 

(c)         Arbitration.

 

(i)       Within
10 days of Tenant’s notice to Landlord of its election to arbitrate Market Rate and escalations, each party shall deliver
to the other a proposal containing the Market Rate and escalations that the submitting party believes to be correct (“Extension
Proposal”). If either party fails to timely submit an Extension Proposal, the other party’s submitted proposal
shall determine the Base Rent and escalations for the Extension Term. If both parties submit Extension Proposals, then Landlord
and Tenant shall meet within 7 days after delivery of the last Extension Proposal and make a good faith attempt to mutually appoint
a single Arbitrator (and defined below) to determine the Market Rate and escalations. If Landlord and Tenant are unable to agree
upon a single Arbitrator, then each shall, by written notice delivered to the other within 10 days after the meeting, select an
Arbitrator, If either party fails to timely give notice of its selection for an Arbitrator, the other party’s submitted proposal
shall determine the Base Rent and escalations for the Extension Term. The 2 Arbitrators so appointed shall, within 5 business days
after their appointment, appoint a third Arbitrator. If the 2 Arbitrators so selected cannot agree on the selection of the third
Arbitrator within the time above specified, then either party, on behalf of both parties, may request such appointment of such
third Arbitrator by application to any state court of general jurisdiction in the jurisdiction in which the Premises are located,
upon 10 days prior written notice to the other party of such intent.

 

(ii)       The
decision of the Arbitrator(s) shall be made within 30 days after the appointment of a single Arbitrator or the third Arbitrator,
as applicable. The decision of the single Arbitrator shall be final and binding upon the parties. The average of the two closest
Arbitrators in a three Arbitrator panel shall be final and binding upon the parties. Each party shall pay the fees and expenses
of the Arbitrator appointed by or on behalf of such party and the fees and expenses of the third Arbitrator shall be borne equally
by both parties. if the Market Rate and escalations are not determined by the first day of the Extension Term, then Tenant shall
pay Landlord Base Rent in an amount equal to the Base Rent in effect immediately prior to the Extension Term and increased by the
Rent Adjustment Percentage until such determination is made. After the determination of the Market Rate and escalations, the parties
shall make any necessary adjustments to such payments made by Tenant. Landlord and Tenant shall then execute and deliver an amendment
recognizing the Market Rate and escalations for the Extension Term.

 

(iii)       An
“Arbitrator” shall be any person appointed by or on behalf of either party or appointed pursuant to the provisions
hereof and: (y) shall be (A) a member of the American Institute of Real Estate Appraisers with not less than 10 years of experience
in the appraisal of improved office and high tech industrial real estate in the greater Gaithersburg-Rockville, Maryland metropolitan
area, or (B) a licensed commercial real estate broker with not less than 15 years’ experience representing landlords and/or
tenants in the leasing of high tech or life sciences space in the greater Gaithersburg-Rockville, Maryland metropolitan area, (z)
devoting substantially all of their time to professional appraisal or brokerage work, as applicable, at the time of appointment
and (iii) be in all respects impartial and disinterested.

 

(d)         Right
Personal. The Extension Right is personal to Tenant and is not assignable without Landlord’s
consent, which may be granted or withheld in Landlord’s sole discretion separate and apart from any consent by Landlord to
an assignment of Tenants interest in this Lease, except that the Extension Right may be assigned in connection with any Permitted
Assignment of this Lease.

 

(e)         Exceptions.
Notwithstanding anything set forth above to the contrary, the Extension Right shall not be in effect and Tenant may not exercise
the Extension Right: (i) during any period of time that Tenant is in

 

    	 	26	 

     

    

  

Default under any provision of this Lease;
or (ii) if Tenant has been in Default under any provision of this Lease 3 or more times, regardless of whether the Defaults are
cured, during the 12 month period immediately prior to the date that Tenant intends to exercise the Extension Right, regardless
of whether the Defaults are cured.

 

(f)       No
Extensions. The period of time within which the Extension Right may be exercised shall not
be extended or enlarged by reason of Tenants inability to exercise the Extension Right.

 

(g)       Termination.
The Extension Right shall terminate and be of no further force or effect even after Tenant’s due and timely exercise of the
Extension Right, if, after such exercise, but prior to the commencement date of the Extension Term, (i) Tenant fails to timely
cure any default by Tenant under this Lease; or (ii) Tenant has Defaulted 3 or more times during the period from the date of the
exercise of the Extension Right to the date of the commencement of the Extension Term, regardless of whether such Defaults are
cured.

 

40.       Generator.
Promptly after the Rent Commencement Date, Landlord shall install a natural gas fired generator with a capacity acceptable to Landlord
(“Generator”) in a location on the roof of the Building acceptable to Landlord for use in connection with Tenant’s
business in the Premises. Landlord shall pay for the cost to install the Generator and all related piping, venting, and metering
devices (collectively, “Generator Equipment”) subject to the provisions of this paragraph. The lesser of $35,000
or fifty percent (50%) of the cost of the Generator Equipment (such amount being referred to herein as “Tenant’s
Portion of the Generator Cost”) shall be fully amortized on a straight line basis with no interest over the Base Term
and reimbursed to Landlord as Additional Rent over the Base Term. Tenant shall reimburse Landlord as Additional Rent for Tenant’s
amortized share of Tenant’s Portion of the Generator Cost (determined as set forth above) in equal monthly installments in
the same manner as the payment by Tenant to Landlord of Tenant’s Share of Operating Expenses. In lieu of paying such amortized
share of Tenant’s Portion of the Generator Cost, Tenant shall have the right, at its sole election, to pay to Landlord as
Additional Rent in a single lump sum the amount of Tenant’s Portion of the Generator Cost. Tenant shall make such election
and payment, if at all, within 30 days after receipt of an invoice from Landlord specifying Tenant’s Portion of the Generator
Cost.

 

(a)       Maintenance.
Tenant shall, at its expense, at all times during the Term maintain with a qualified contractor a maintenance and repair contract
(“Maintenance Contract”) for the Generator. The Maintenance Contract shall be in form and content reasonably
satisfactory to Landlord. Landlord shall be a third party beneficiary of the Maintenance Contract and, within 30 days after Landlord’s
request, Tenant shall deliver a copy of the Maintenance Contract to Landlord.

 

(b)       Testing.
Tenant shall be allowed to test the Generator once a week at a time mutually agreed to by Landlord and Tenant. Tenant shall immediately
take all necessary actions to prevent the Generator from causing any adverse effects to the air quality of the Building. No promotional
or advertising matter or signage shall be attached to, painted, or displayed on the Generator.

 

(c)       Installation;
Maintenance; Removal. Tenant shall, at its sole cost and expense, properly maintain and repair
the Generator Equipment. Tenant shall be responsible for connecting the Generator to the electrical supply system serving the Premises
in accordance with the requirements of Landlord’s electrical engineer/contractor, At the expiration or earlier termination
of the Term, the Generator shall remain at the Project and Tenant shall return the Generator to Landlord in the condition it was
in prior to the installation of the Generator. Tenant shall pay all governmental fees, charges, and taxes and all hook-up and disconnection
fees associated with Tenant’s use of the Generator and Landlord shall have no liability therefor. Ali of the provisions of
this Lease, including, without limitation, the insurance, maintenance, repair, release, and indemnification provisions set forth
in this Lease shall apply and be applicable to Tenant’s installation, operation, maintenance, and removal of the Generator.
Landlord shall, at its sole cost and expense, secure all necessary permits and approvals from all applicable Governmental Authorities
for the size, placement and installation of the Generator. if Landlord is unable to obtain the necessary approvals and permits
from any Governmental Authorities for the Generator, Tenant shall have no remedy, claim, cause of action, or recourse against Landlord,
nor shall such failure or inability to obtain any necessary permits or approvals provide Tenant the right to terminate this Lease.
Tenant shall cooperate with Landlord in securing all necessary permits and approvals for the Generator. Without limiting any other
obligations of Tenant set forth in this Lease, Tenant shall, at its sole cost and expense, maintain and repair the Generator and
keep it in good order and operating condition.

 

    	 	27	 

     

    

  

(d)       Insurance.
If the presence of the Generator Equipment is the sole cause of an increase in Landlord’s property or liability insurance
premiums for the Building, Landlord shall so inform Tenant in writing and Tenant shall pay to Landlord as Additional Rent within
10 days after demand therefor an amount equal to such increase.

 

(e)       Compliance.
Tenant shall, at its sole cost and expense, comply with all Legal Requirements that may now or hereafter be applicable to the area
in which the Generator shall be located or to the use, operation, repair, maintenance, and replacement of the Generator. The Legal
Requirements include, but are not limited to, Legal Requirements (i) requiring that Tenant obtain the necessary permits and approvals
for the use, operation, repair, maintenance, and replacement of the Generator, (ii) prohibiting any form of pollution, OH) requiring
the person discharging or permitting the discharging of Hazardous Materials or participating in the discharge or spilling of Hazardous
Materials to report such discharge or spill to the proper Governmental Authorities, (iv) requiring certain inspections, gauging,
and recordkeeping. Tenant shall pay all costs, expenses, claims, fines, penalties, and damages that may in any manner arise out
of or be imposed because of the failure of Tenant to comply with this Section. Tenant shall indemnify, defend, and hold harmless
Landlord and its officers, members, directors, employees, managers, employees, agents, and contractors from all claims, injuries,
damages, costs, expenses, losses, and liabilities (including, but not limited to, attorneys’ fees) arising from Tenant’s
failure to comply with this Section. Each party shall promptly give notice to the other of any notice of violation received by
each party. Tenant shall retain all right, title, and interest in and to the Generator and all related infrastructure (including,
but not limited to, piping, venting, and metering devices) during the Term, and Landlord hereby disclaims any right, title, and
interest in and to the Generator Equipment.

 

(f)       Temporary
Generator. Within ‘10 days after the Commencement Date and until such time that Landlord
causes the Generator Equipment to be installed, Landlord shall: (i) provide a temporary standby generator (“Temporary
Generator”) to service the freezers and other laboratory equipment located in the Premises, and (ii) contract with a
third party to maintain the Temporary Generator as per the manufacturer’s standard maintenance guidelines. Landlord shall
have no obligation to provide back-up power or to supervise, oversee, or confirm that the third party maintaining the Temporary
Generator is maintaining the Temporary Generator as per the manufacturer’s standard guidelines or otherwise. Tenant expressly
acknowledges and agrees that Landlord does not guaranty that the Temporary Generator will be operational at all times or that emergency
power will be available to the Premises when needed.

 

41.       Miscellaneous.

 

(a)       Notices.
All notices or other communications between the parties shall be in writing and shall be deemed duly given upon delivery or refusal
to accept delivery by the addressee thereof if delivered in person, or upon actual receipt if delivered by reputable overnight
guaranty courier, addressed and sent to the parties at their addresses set forth above. Landlord and Tenant may from time to time
by written notice to the other designate another address for receipt of future notices.

 

(b)       Joint
and Several Liability. If and when included within the term “Tenant,” as
used in this instrument, there is more than one person or entity, each shall be jointly and severally liable for the obligations
of Tenant.

 

(c)       Financial
Information. As a material inducement for Landlord to enter into this Lease, Tenant has agreed
to provide Landlord with the financial information set forth in this paragraph within the time periods provided herein, WITH TIME
BEING STRICTLY OF THE ESSENCE. Landlord must receive this information timely so that it can monitor Tenants financial condition
and performance without any delays. Tenant shall furnish Landlord with true and complete copies of (I) Tenants most recent audited
annual financial statements within 60 days of the end of each of Tenant’s fiscal years during the Term, (ii) Tenants most
recent unaudited monthly financial statements within 10 days of the end of each month during the Term, (iii) Tenant’s most
recent unaudited quarterly financial statements within 30 days of the end of each of Tenants first three fiscal quarters of each
of Tenant’s fiscal years during the Term, (iv) within 5 business days after Landlord’s request from time to time, updated
business plans, including cash flow projections and/or pro forma balance sheets and income statements, all of which shall be treated
by Landlord as confidential information belonging to Tenant, (v) corporate brochures

 

    	 	28	 

     

    

  

and/or profiles prepared by Tenant for prospective
investors, and (vi) any other financial information or summaries that Tenant typically provides to its lenders or shareholders,

 

(d)       Recordation.
Neither this Lease nor a memorandum of lease shall be filed by or on behalf of Tenant in any public record_ Landlord may prepare
and file, and upon request by Landlord Tenant will execute, a memorandum of (ease.

 

(e)       Interpretation.
The normal rule of construction to the effect that any ambiguities are to be resolved against the drafting party shall not be employed
in the interpretation of this Lease or any exhibits or amendments hereto. Words of any gender used in this Lease shall be held
and construed to include any other gender, and words in the singular number shall be held to include the plural, unless the context
otherwise requires. The captions inserted in this Lease are for convenience only and in no way define, limit or otherwise describe
the scope or intent of this Lease, or any provision hereof, or in any way affect the interpretation of this Lease.

 

(f)       Not
Binding Until Executed. The submission by Landlord to Tenant of this Lease shall have no binding
force or effect, shall not constitute an option for the leasing of the Premises, nor confer any right or impose any obligations
upon either party until execution of this Lease by both parties.

 

(g)       Limitations
on Interest. It is expressly the intent of Landlord and Tenant at all times to comply with applicable law governing the maximum
rate or amount of any interest payable on or in connection with this Lease. If applicable law is ever judicially interpreted so
as to render usurious any interest called for under this Lease, or contracted for, charged, taken, reserved, or received with respect
to this Lease, then it is Landlord’s and Tenants express intent that all excess amounts theretofore collected by Landlord
be credited on the applicable obligation (or, if the obligation has been or would thereby be paid in full, refunded to Tenant),
and the provisions of this Lease immediately shall be deemed reformed and the amounts thereafter collectible hereunder reduced,
without the necessity of the execution of any new document, so as to comply with the applicable law, but so as to permit the recovery
of the fullest amount otherwise called for hereunder.

 

(h)       Choice
of Law. Construction and interpretation of this Lease shall be governed by the internal laws
of the state in which the Premises are located, excluding any principles of conflicts of laws.

 

(i)       Time.
Time is of the essence as to the performance of each party’s obligations under this Lease.

 

(j)       OFAC.
Tenant, and all beneficial owners of Tenant, are currently (i) in compliance with and shall at all times during the Term of this
Lease remain in compliance with the regulations of the Office of Foreign Assets Control (“OFAC”) of the U.S.
Department of Treasury and any statute, executive order, or regulation relating thereto (collectively, the “OFAC Rules”),
(ii) not listed on, and shall not during the Term of this Lease be listed on, the Specially Designated Nationals and Blocked Persons
List maintained by OFAC and/or on any other similar list maintained by OFAC or other governmental authority pursuant to any authorizing
statute, executive order, or regulation, and (iii) not a person or entity with whom a U.S. person is prohibited from conducting
business under the OFAC Rules.

 

(k)       Incorporation
by Reference. Ali exhibits and addenda attached hereto are hereby incorporated into this Lease
and made a part hereof. If there is any conflict between such exhibits or addenda and the terms of this Lease, such exhibits or
addenda shall control.

 

(l)       No
Accord and Satisfaction. No payment by Tenant or receipt by Landlord of a lesser amount than
the monthly installment of Base Rent or any Additional Rent will be other than on account of the earliest stipulated Base Rent
arid Additional Rent, nor will any endorsement or statement on any check or letter accompanying a check for payment of any Base
Rent or Additional Rent be an accord and satisfaction, Landlord may accept such check or payment without prejudice to Landlord’s
right to recover the balance of such Rent or to pursue any other remedy provided in this Lease.

 

(m)       Non-Disclosure
of Terms. Tenant acknowledges and agrees that the terms of this Lease are confidential and
constitute proprietary information of Landlord. Disclosure of such terms could adversely affect the

 

    	 	29	 

     

    

  

ability of Landlord and its affiliates to negotiate,
manage, and administer other leases and impair Landlord’s relationship with other tenants. Accordingly, as a material inducement
for Landlord to enter into this Lease, Tenant, and behalf of itself and its partners, managers, members, officers, directors, employees,
agents, and attorneys, agrees that it shall not intentionally and voluntarily (a) disclose the terms and conditions of this Lease
to any publication or other media or any tenant or apparent prospective tenant of the Building or other portion of the Project,
or real estate agent or broker, either directly or indirectly, or (b) post or place on any website or other form of media, directly
or indirectly, any of the terms and conditions of this Lease or opine or critique Landlord’s management ownership abilities
and skills.

 

(n)       Hazardous
Activities. Notwithstanding any other provision of this Lease, Landlord, for itself and its
employees, agents and contractors, reserves the right to refuse to perform any repairs or services in any portion of the Premises
which, pursuant to Tenant’s routine safety guidelines, practices or custom or prudent industry practices, require any form
of protective clothing or equipment other than safety glasses. In any such case, Tenant shall contract with parties who are acceptable
to Landlord, in Landlord’s reasonable discretion, for all such repairs and services, and Landlord shall equitably adjust
Tenant’s Share of Operating Expenses in respect of such repairs or services to reflect that Landlord is not providing such
repairs or services to Tenant.

 

[ Signatures on next page ]

 

    	 	30	 

     

    

  

IN WITNESS WHEREOF, Landlord
and Tenant have executed this Lease under seal as of the day and year first above written.

 

	 	TENANT:	 
	 	 	 
	 	GENVEC, INC.,	 
	 	a Delaware corporation	 
	 	 	 	 
	 	By:	/s/ Douglas J. Swirsky	(SEAL)
	 	Its:	Chief Executive Officer	 

 

	 	LANDLORD:
	 	 	 	 	 
	 	ARE-MARYLAND NO. 30, LLC,
	 	a Maryland limited liability company
	 	 	 	 	 
	 	By:	ARE-Maryland No. 29, LLC,
	 	 	 	a Maryland limited liability company,
	 	 	 	as its sole member
	 	 	 	 	 
	 	 	By:	Alexandria Real Estate Equities, L.P.,
	 	 	 	 	a Delaware limited partnership,
	 	 	 	 	as its sole member
	 	 	 	 	 
	 	 	 	By:	ARE-QRS CORP.,
	 	 	 	 	a Maryland corporation,
	 	 	 	 	general partner

  

	 	By: 	/s/ Jennifer Banks	(SEAL)

	 	Name: 	Jennifer Banks	 

	 	Title: 	EVP, General Counsel	 

 

    	 	31	 

     

    

  

EXHIBIT A TO LEASE

DESCRIPTION OF PREMISES

 

 

220-N FLOOR. PLAN

 

    	 	32	 

     

    

  

EXHIBIT B TO LEASE

DESCRIPTION OF PROJECT

 

Parcel “V-1” in a subdivision known
as “Pheasant Run” as per plat thereof recorded in Plat Book 112 at plat 13224 among the Land Records of Montgomery
County, Maryland, bearing a street address of 910 Clapper Road, Gaithersburg, Maryland 20879.

 

    	 	33	 

     

    

  

EXHIBIT C TO LEASE 

WORK LETTER

 

Landlord shall, at its expense, Deliver the
Premises to Tenant in a vacant and broom clean condition. All electrical systems (including any electrical panels serving the Premises),
base building lighting, water service plumbing fixtures, life safety, mechanical, and systems distribution fixtures within the
Premises and the Building shall be in good operating order and condition as of the Rent Commencement Date. Any such work that must
be done by Landlord to satisfy the foregoing shall be defined as “Landlord’s Work.”

 

    	 	34	 

     

    

  

EXHIBIT D TO LEASE

ACKNOWLEDGMENT OF COMMENCEMENT DATE

 

This ACKNOWLEDGMENT
OF COMMENCEMENT DATE is made as of this ____ day of ____________, 201_, between ARE-MARYLAND NO. 30, LLC, a Delaware
limited liability company (“Landlord”), and GENVEC, INC., a Delaware corporation (“Tenant”),
and is attached to and made a part of the Lease Agreement dated as of November __, 2013 (“Lease”), by and between
Landlord and Tenant. Any initially capitalized terms used but not defined herein shall have the meanings given them in the Lease.

 

Landlord and Tenant hereby
acknowledge and agree that the Commencement Date of the Base Term of the Lease is November , 2013, the Rent Commencement Date is
December 1, 2013 (subject to the Rental Abatement set forth in Section 4(a) of the Lease), and the expiration date of the Base
Term of the Lease shall be midnight on October 31, 2019. In case of a conflict between the terms of the Lease and the terms of
this Acknowledgement of Commencement Date, this Acknowledgement of Commencement Date shall control for all purposes.

 

IN WITNESS WHEREOF, Landlord
and Tenant have executed this ACKNOWLEDGMENT OF COMMENCEMENT DATE under seal to be effective on the date first above written.

 

	 	TENANT:	 
	 	 	 
	 	GENVEC, INC.,	 
	 	a Delaware corporation	 
	 	 	 	 
	 	By:	 	(SEAL)
	 	Its:	 	 

 

	 	LANDLORD:
	 	 	 	 	 
	 	ARE-MARYLAND NO. 30, LLC,
	 	a Maryland limited liability company
	 	 	 	 	 
	 	By:	ARE-Maryland No. 29, LLC,
	 	 	 	a Maryland limited liability company,
	 	 	 	as its sole member
	 	 	 	 	 
	 	 	By:	Alexandria Real Estate Equities, L.P.,
	 	 	 	 	a Delaware limited partnership,
	 	 	 	 	as its sole member
	 	 	 	 	 
	 	 	 	By:	ARE-QRS CORP.,
	 	 	 	 	a Maryland corporation,
	 	 	 	 	general partner

 

	 	By:	 	(SEAL)

	 	Name:	 	 

	 	Title:	 	 

 

    	 	35	 

     

    

  

EXHIBIT E TO LEASE

Rules and Regulations

 

1.       The
sidewalk, entries, and driveways of the Project shall not be obstructed by Tenant, or any Tenant Party, or used by them for any
purpose other than ingress and egress to and from the Premises.

 

2.       Tenant
shall not place any objects, including antennas, outdoor furniture, etc., in the parking areas, landscaped areas or other areas
outside of its Premises, or on the roof of the Project.

 

3.       Except
for animals assisting the disabled, no animals shall be allowed in the offices, halls, or corridors in the Project.

 

4.       Tenant
shall not disturb the occupants of the Project or adjoining buildings by the use of any radio or musical instrument or by the making
of loud or improper noises.

 

5.       If
Tenant desires telegraphic, telephonic or other electric connections in the Premises, Landlord or its agent will direct the electrician
as to where and how the wires may be introduced; and, without such direction, no boring or cutting of wires will be permitted.
Any such installation or connection shall be made at Tenant’s expense.

 

6.       Tenant
shall not install or operate any steam or gas engine or boiler, or other mechanical apparatus in the Premises, except as specifically
approved in the Lease. The use of oil, gas or inflammable liquids for heating, lighting or any other purpose is expressly prohibited.
Explosives or other articles deemed extra hazardous shall not be brought into the Project.

 

7.       Parking
any type of recreational vehicles is specifically prohibited on or about the Project. Except for the overnight parking of operative
vehicles, no vehicle of any type shall be stored in the parking areas at any time. In the event that a vehicle is disabled, it
shall be removed within 48 hours. There shall be no “For Sale” or other advertising signs on or about any parked vehicle.
Ali vehicles shall be parked in the designated parking areas in conformity with all signs and other markings. All parking will
be open parking, and no reserved parking, numbering or lettering of individual spaces will be permitted except as specified by
Landlord.

 

8.       Tenant
shall maintain the Premises free from rodents, insects and other pests.

 

9.       Landlord
reserves the right to exclude or expel from the Project any person who, in the judgment of Landlord, is intoxicated or under the
influence of liquor or drugs or who shall in any manner do any act in violation of the Rules and Regulations of the Project.

 

10.       Tenant
shall not cause any unnecessary labor by reason of Tenant’s carelessness or indifference in the preservation of good order
and cleanliness. Landlord shall not be responsible to Tenant for any loss of property on the Premises, however occurring, or for
any damage done to the effects of Tenant by the janitors or any other employee or person.

 

11.       Tenant
shall give Landlord prompt notice of any defects in the water, lawn sprinkler, sewage, gas pipes, electrical lights and fixtures,
heating apparatus, or any other service equipment affecting the Premises.

 

12.       Tenant
shall not permit storage outside the Premises, including without limitation, outside storage of trucks and other vehicles, or dumping
of waste or refuse or permit any harmful materials to be placed in any drainage system or sanitary system in or about the Premises.

 

13.       All
moveable trash receptacles provided by the trash disposal firm for the Premises must be kept in the trash enclosure areas, if any,
provided for that purpose.

 

14.       No
auction, public or private, will be permitted on the Premises or the Project.

 

    	 	36	 

     

    

  

15.       No
awnings shall be placed over the windows in the Premises except with the prior written consent of Landlord.

 

16.       The
Premises shall not be used for lodging, sleeping or cooking or for any immoral or illegal purposes or for any purpose other than
that specified in the Lease. No gaming devices shall be operated in the Premises.

 

17.       Tenant
shall ascertain from Landlord the maximum amount of electrical current which can safely be used in the Premises, taking into account
the capacity of the electrical wiring in the Project and the Premises and the needs of other tenants, and shall not use more than
such safe capacity. Landlord’s consent to the installation of electric equipment shall not relieve Tenant from the obligation
not to use more electricity than such safe capacity.

 

18.       Tenant
assumes full responsibility for protecting the Premises from theft, robbery and pilferage.

 

19.       Tenant
shall not install or operate on the Premises any machinery or mechanical devices of a nature not directly related to Tenant’s
ordinary use of the Premises and shall keep all such machinery free of vibration, noise and air waves which may be transmitted
beyond the Premises.

 

    	 	37	 

     

    

  

EXHIBIT F TO LEASE

TENANT’S PERSONAL
PROPERTY

 

None except as set forth below:

 

NONE

 

    	 	38	 

     

    

  

EXHIBIT G TO LEASE

NOTIFICATION OF THE PRESENCE OF ASBESTOS
CONTAINING MATERIALS

 

This notification provides certain information
about asbestos within or about the Premises at 910 Clapper Road, Gaithersburg, Maryland (“Building”).

 

Historically, asbestos was commonly used in
building products used in the construction of buildings across the country. Asbestos-containing building products were used because
they are fire-resistant and provide good noise and temperature insulation. Because of their prevalence, asbestos-containing materials,
or ACMs, are still sometimes found in buildings today.

 

Asbestos surveys of the Building have determined
that ACMs and/or materials that might contain asbestos, referred to as presumed asbestos-containing materials or PACMs, are present
within or about the Premises. The surveys found ACMs and/or PACMs of the types, in the amounts and at the following location(s)
in or about the Premises:

 

	Material
    Description	 	Material Location
	12’ beige floor tile and mastic	 	Janitor’s closets and stairwells
	Tan duct seam sealant	 	Above ceiling, on main trunk duct
	Grey textured paint	 	Roof, on air handler baffle wall
	Black duct seam sealant	 	Roof, on ducts
	Mastic beneath 12” white with multi-colored mottle floor tile	 	Janitor’s closet by 2nd floor former Intronn Suite
	Brown expansion joint caulk	 	Throughout building

 

Because ACMs and PACMs are present and may
continue to be present within or about the Building, we have hired an independent environmental consulting firm to prepare an operations
and maintenance program (“O&M Program”). The O&M Program is designed to minimize the potential of any
harmful asbestos exposure to any person within or about the Building. The O&M Program includes a description of work methods
to be taken in order to maintain any ACMs or PACMs within or about the Building in good condition and to prevent any significant
disturbance of such ACMs or PACMs. Appropriate personnel receive regular periodic training on how to properly administer the O&M
Program,

 

The O&M Program describes the risks associated
with asbestos exposure and how to prevent such exposure through appropriate work practices. ACMs and PACMs generally are not thought
to be a threat to human health unless asbestos fibers are released into the air and inhaled. This does not typically occur unless
(1) the ACMs are in a deteriorating condition, or (2) the ACMs have been significantly disturbed (such as through abrasive cleaning,
or maintenance or renovation activities). If inhaled, asbestos fibers can accumulate in the lungs and, as exposure increases, the
risk of disease (such as asbestosis or cancer) increases. However, measures to minimize exposure, and consequently minimize the
accumulation of asbestos fibers, reduce the risks of adverse health effects.

 

The O&M Program describes a number of activities
that should be avoided in order to prevent a release of asbestos fibers. In particular, you should be aware that some of the activities
which may present a health risk include moving, drilling, boring, or otherwise disturbing ACMs. Consequently, such activities should
not be attempted by any person not qualified to handle ACMs.

 

The O&M Program is available for review
during regular business hours at Landlord’s office located at 946 Clapper Road, Gaithersburg, Maryland 20878.

 

    	 	39Exhibit 10.29

 

FIRST AMENDMENT TO LEASE AGREEMENT

 

THIS FIRST AMENDMENT
TO LEASE AGREEMENT (“this First Amendment”) is dated as of December 19, 2014 (“Effective Date”),
by and between ARE-MARYLAND NO. 30, LLC, a Maryland limited liability company, having an address at 385 E. Colorado Blvd.,
Suite 299, Pasadena, California 91101 (“Landlord”), and GENVEC, INC., a Delaware corporation, having
an address at Suite 220N, 910 Clopper Road, Gaithersburg, Maryland 20878 (“Tenant”).

 

RECITALS

 

A.      Landlord
and Tenant have entered into that certain Lease Agreement (“Lease”) dated as of November 15, 2013 between Landlord
and Tenant, wherein Landlord leased to Tenant certain premises (“Original Premises”) located at Suite 220N,
910 Clopper Road, Gaithersburg, Maryland 20878, as more particularly described in the Lease.

 

B.       Landlord
and Tenant desire to amend the Lease, among other things, to lease to Tenant an additional 2,290 rentable square feet on the second
floor of the Building as shown as the cross-hatched area on Exhibit A attached hereto located at Suite 260S, 910 Clopper
Road, Gaithersburg, Maryland 20878 (“Expansion Premises”; the Original Premises and the Expansion Premises are
hereinafter collectively referred to as the “Premises”), and to provide a tenant improvement allowance for use
in the Expansion Premises.

 

AGREEMENT

 

Now, therefore, the
parties hereto agree that the Lease is amended as follows:

 

1.       Definitions;
Recitals. Terms used in this First Amendment but not otherwise defined shall have the meanings set forth in the Lease. The
Recitals form an integral part of this First Amendment and are hereby incorporated by reference.

 

2.       Expansion
Premises. Effective as of the Expansion Premises Commencement Date (as defined below), (a) the Original Premises shall be
expanded to include the Expansion Premises, and (b) Exhibit A to this First Amendment, which depicts the Expansion Premises as
the cross-hatched area as well as the Original Premises, hereby replaces Exhibit A to the Lease.

 

3.       Changes
to Defined Terms. Effective as of the Expansion Premises Commencement Date, the following amendments are hereby made to the
definitions contained on page 1 of the Lease in the Basic Lease Provisions.

 

		a.	The defined term “Premises” shall be deleted in its entirety and replaced with
the following:

 

		“Premises:	That portion of the Project, containing approximately 8,779 rentable square feet, as determined
by Landlord, consisting of (i) approximately 6,489 rentable square feet of space

 

     

     

    

 

shown on Exhibit A to
the Original Lease (“Original Premises”), and (ii) approximately 2,290 rentable square feet of space shown as
the hatched area on Exhibit A attached to the First Amendment to Lease Agreement between Landlord and Tenant (“Expansion
Premises”). Gaudreau, Inc., Landlord’s architect, has measured the area of the Premises pursuant to the 1996 Standard
Method of Measuring Floor Area in Office Buildings as adopted by the Building Owners and Managers Association (ANSI/BOMA Z65.1-1996).
Tenant acknowledges receipt of such measurement and confirms that (a) Tenant has had an opportunity to confirm such measurement
with an architect of its selection before the Effective Date, and (b) such measurement shall be conclusive as to the area of the
Premises.”

 

		b.	The defined term “Rentable Area of the Premises” shall mean approximately 8,779
rentable square feet.

 

		c.	The defined term “Tenant’s Share of Operating Expenses” shall mean 4.86%.

 

4.       Delivery
of Expansion Premises. Landlord shall use reasonable efforts to deliver the Expansion Premises to Tenant by December 31, 2014
in their “as is” condition (“Delivery” or “Deliver”). The date on which Landlord
Delivers the Expansion Premises to Tenant is referred to as the “Expansion Premises Commencement Date.” Upon
request of Landlord, Tenant shall execute and deliver a written acknowledgement of the Expansion Premises Commencement Date when
the same is established in a form substantially similar to the form of “Acknowledgment of Commencement Date” attached
hereto as Exhibit B; provided, however, that Tenant’s failure to execute and deliver such acknowledgement
shall not affect Landlord’s rights under this First Amendment. If Landlord fails to Deliver timely the Expansion Premises,
Landlord shall not be liable to Tenant for any loss or damage resulting therefrom, and this First Amendment and the Lease with
respect to the Expansion Premises shall not be void or voidable.

 

a.       Acceptance.
Except as set forth in this paragraph: (i) Tenant shall accept the Expansion Premises in their condition as of the Expansion
Premises Commencement Date; (ii) Landlord shall have no obligation for any defects in the Expansion Premises, and (iii) Tenant’s
taking possession of the Expansion Premises shall be conclusive evidence that Tenant accepts the Expansion Premises and that the
Expansion Premises were in good condition at the time possession was taken. Notwithstanding the foregoing provisions of this paragraph,
Landlord shall, at its expense, Deliver the Expansion Premises to Tenant on the Expansion Premises Commencement Date in a broom
clean condition free and clear of all tenancies. All electrical systems (including any electrical panels serving the Expansion
Premises), base building lighting, water service, plumbing fixtures, life safety, mechanical and systems distribution fixtures
within the Expansion Premises and Building shall be in good operating order and condition as of the Expansion Premises Commencement
Date.

 

    	 	2	 

     

    

 

 

b.       No
Representation or Warranty. Tenant agrees and acknowledges that neither Landlord nor any agent of Landlord has made any representation
or warranty with respect to the condition of all or any portion of the Expansion Premises, and/or the suitability of the Expansion
Premises for the conduct of Tenant’s business, and Tenant waives any implied warranty that the Expansion Premises are suitable
for the Permitted Use. Tenant shall use the Expansion Premises only for the Permitted Use under the Lease in compliance with the
provisions of Section 6 of the Lease.

 

c.       No
Work. Landlord shall have no obligation to perform any work at the Building, other than as set forth in Section 4.a above,
in connection with Tenant’s occupancy of the Expansion Premises or obtain any permits, approvals, or entitlements related
to Tenant’s specific use of the Expansion Premises or Tenant’s business operations therein.

 

d.       Future
Alterations. Tenant shall have the right, at its sole cost and expense, to modify the Expansion Premises from and after the
Expansion Premises Commencement Date and build out a higher ratio of office to laboratory space or vice-versa (“Future
Alterations”). Tenant’s design and construction of the Future Alterations shall constitute Alterations and shall
be made in strict accordance with the applicable provisions of the Lease, including, but not limited to, Section 14 (Alterations
and Tenant’s Property).

 

5.       Base
Rent for Expansion Premises. (a) Tenant shall continue to pay Base Rent with respect to the Existing Premises at the rates
set forth in the Lease, and (b) commencing January 1, 2015 (“Expansion Premises Rent Commencement Date”) and
subject to the Rental Abatement (as defined below), Base Rent for the Expansion Premises shall be payable at the rate of $2,385.42
per month and shall, notwithstanding any contrary provision contained in the Lease, thereafter be increased on each anniversary
of the Expansion Premises Rent Commencement Date by multiplying the Base Rent payable for the Expansion Premises immediately before
such date by the Rent Adjustment Percentage (i.e., 3%) and adding the resulting amount to the Base Rent payable for the Expansion
Premises immediately before such date. Base Rent for the Expansion Premises, as so adjusted, shall thereafter be due as provided
in the Lease.

 

a.       Base
Rent Abatement. Provided Tenant is not then in Default under this First Amendment or the Lease, Landlord hereby grants Tenant
an abatement (“Rental Abatement”) of the Base Rent payable for the Expansion Premises for a period of 2 full
calendar months beginning on the Expansion Premises Rent Commencement Date and ending on February 28, 2015. Thereafter, Tenant
shall pay the full amount of Base Rent due in accordance with the provisions of this First Amendment and the Lease. The Rental
Abatement is conditioned on Tenant’s full and faithful performance of all of the terms, covenants, and conditions of the
Lease to be performed and observed by Tenant during the Term. On the occurrence of a Default by Tenant and in addition to any
other rights and remedies available to Landlord under the Lease, the Rental Abatement shall automatically be deemed deleted from
this First Amendment and the Lease and of no future force or effect, and the Rental Abatement so given by Landlord shall be prorated
with that portion of the Rental Abatement applicable to the remaining Term being immediately due and payable by Tenant to Landlord,
and recoverable by Landlord as Additional Rent due under the Lease, on the termination of the Lease. The acceptance by Landlord
of Rent or the cure of the Default that initiated the operation of this paragraph shall not be deemed a waiver by Landlord of
the provisions of this paragraph unless specifically so stated

 

    	 	3	 

     

    

 

in writing by Landlord
at the time of such acceptance. Notwithstanding anything to the contrary in this First Amendment or the Lease, the adjustment in
the Base Rent for the Expansion Premises shall be based on the full and unabated amount of Base Rent payable with respect to the
Expansion Premises for the first year after the Expansion Premises Rent Commencement Date.

 

6.       TI
Allowance. Landlord shall provide to Tenant a tenant improvement allowance in an amount equal to $75,000 in the aggregate
(“TI Allowance”), to be used by Tenant as set forth in this Section 6. Other than funding the TI Allowance
and performing the Tenant Improvements (as defined below), Landlord shall have no other obligation whatsoever with respect to
making any leasehold or other improvements to the Expansion Premises. Landlord’s obligations with respect to the T1 Allowance
and the Tenant Improvements shall cease upon disbursement in full of the TI Allowance. The TI Allowance shall be used to reimburse
Landlord for any expenses associated with modifications of or improvements to the Expansion Premises of a fixed and permanent
nature desired by Tenant (including the design and installation cost of such modifications or improvements, the cost of painting
and installing new carpeting or flooring, or the cost to install an electrical submeter for the Expansion Premises) and that are
approved by Landlord (“Tenant Improvements”) but shall not be used to purchase any furniture, personal property,
or other non-Building Systems materials or equipment.

 

a.       Base
Rent Adjustment for TI Allowance. Base Rent shall be increased as of the date or dates on which Landlord draws on the TI Allowance
pursuant to, and as defined in, this Section 6 by amortizing the amount(s) so paid over the period beginning on the date on which
Landlord initially draws on the TI Allowance and continuing through the expiration of the Base Term. Such increase in Base
Rent shall be calculated based on the amount of the TI Allowance drawn and actually paid, transferred, or otherwise made available
to Tenant. The resulting amount so amortized shall be added to the monthly installments of Base Rent and shall be paid regardless
of the Rental Abatement. Each draw made by Landlord of the Ti Allowance shall accrue interest at 8.5% per annum from the date
of the draw until the date on which such draw is repaid in full.

 

b.       Request;
Approval Process. By no later than 180 days after the Expansion Premises Commencement Date, Tenant shall notify Landlord in
writing whether Tenant desires Landlord to perform any Tenant Improvements and to use all or a part of the TI Allowance. If Tenant
does not so notify Landlord by such date, Tenant shall have no right to use all or any portion of the TI Allowance. If Tenant
so notifies Landlord by such date, Tenant shall provide to Landlord for Landlord’s review and approval within 30 days after
the date of such notice, (i) a schematic drawing and outline specifications detailing the Tenant Improvements (“Specifications”),
and a detailed breakdown of the costs relating to the Tenant Improvements (“Budget”). Landlord shall respond
to Tenant regarding Landlord’s approval or disapproval of the Specifications and Budget, within 10 business days after Landlord’s
receipt thereof, and in the case of Landlord’s disapproval of the proposed Specifications and/or Budget, Landlord shall
provide Tenant with written objections, questions, or comments. Tenant shall cause the proposed Specifications and/or Budget to
be revised to address such written comments and shall submit the revised Specifications and/or Budget to Landlord for approval
within 10 days thereafter. Such process shall continue until Landlord has approved such Specifications and Budget, after which
approval neither the Specifications nor the Budget shall be modified without Landlord’s

 

    	 	4	 

     

    

 

written approval. Landlord
may cause the Tenant Improvements to be performed during Tenant’s business hours, but Landlord shall use commercially reasonable
efforts to minimize any disruption to Tenant’s business operations in the Expansion Premises. Landlord shall have no obligation
to, and shall not, secure any permits, approvals, or entitlements related to Tenant’s specific use of the Expansion Premises
or Tenant’s business operations therein.

 

c.       Draws.
Landlord shall draw from the TI Allowance the costs and expenses incurred by or on behalf of Landlord in performing the Tenant
Improvements as well as a management fee equal to 3% of the costs and expenses incurred to perform the Tenant Improvements. Such
management fee covers Landlord’s overhead and expenses for plan review, coordination, scheduling and supervision. If the
costs and expenses to perform the Tenant Improvements are in excess of the TI Allowance, Tenant shall pay such excess costs and
expenses to Landlord as additional rent within 15 days after request therefor.

 

d.       Title
to Improvements. Title to the Tenant Improvements paid for out of the TI Allowance shall vest in and remain in the sole name
of Landlord and shall not be subject to any liens or encumbrances. On the expiration or earlier termination of the Term, Tenant
shall surrender possession of the Tenant Improvements to Landlord. During the Term, Tenant shall maintain the Tenant Improvements
in good order, condition, and repair (ordinary wear and tear excepted).

 

7.       Miscellaneous.

 

a.       Entire
Agreement. This First Amendment is the entire agreement between the parties with respect to the subject matter hereof and
supersedes all prior and contemporaneous oral and written agreements and discussions. This First Amendment may be amended only
by an agreement in writing, signed by the parties hereto.

 

b.       Binding
Effect. This First Amendment is binding upon and shall inure to the benefit of the parties hereto, their respective agents,
employees, members, representatives, officers, directors, divisions, subsidiaries, affiliates, assigns, heirs, successors in interest
and shareholders.

 

c.       Counterparts.
This First Amendment may be executed in any number of counterparts, each of which shall be deemed an original, but all of
which when taken together shall constitute one and the same instrument. The signature page of any counterpart may be detached
therefrom without impairing the legal effect of the signature(s) thereon provided such signature page is attached to any other
counterpart identical thereto except having additional signature pages executed by other parties to this First Amendment attached
thereto.

 

d.       Broker.
Landlord and Tenant each represents and warrants that it has not dealt with any broker, agent or other person (collectively,
“Broker”) in connection with this transaction and that no Broker brought about this transaction, other than
Edge Commercial, as Landlord’s broker, and Jones Lang LaSalle Brokerage, Inc., as Tenant’s broker (“JLL”).
Edge Commercial shall be paid by Landlord pursuant to a separate agreement between Edge Commercial and Landlord. JLL shall
be paid pursuant to a separate agreement between Edge Commercial and JLL. Landlord and Tenant each hereby agrees to indemnify
and hold the other

 

    	 	5	 

     

    

 

harmless from and against
any claims by any Broker, other than Edge Commercial and JLL, claiming a commission or other form of compensation by virtue of
having dealt with Tenant or Landlord, as applicable, with regard to this leasing transaction.

 

e.       Ratification;
Conflicts. Except as amended and/or modified by this First Amendment, the Lease is hereby ratified and confirmed and all other
terms of the Lease shall remain in full force and effect, unaltered and unchanged by this First Amendment. In the event of any
conflict between the provisions of this First Amendment and the provisions of the Lease, the provisions of this First Amendment
shall prevail. Regardless of whether specifically amended by this First Amendment, all of the terms and provisions of the Lease
are hereby amended to the extent necessary to give effect to the purpose and intent of this First Amendment.

 

f.       Non-Disclosure
of Terms. Tenant acknowledges and agrees that the terms of the Lease are confidential and constitute proprietary information
of Landlord. Disclosure of such terms could adversely affect the ability of Landlord and its affiliates to negotiate, manage,
and administer other leases and impair Landlord’s relationship with other tenants. Accordingly, as a material inducement
for Landlord to enter into this First Amendment, Tenant, and behalf of itself and its partners, managers, members, officers, directors,
employees, agents, and attorneys, agrees that it shall not intentionally and voluntarily (i) disclose the terms and conditions
of the Lease to any publication or other media or any tenant or apparent prospective tenant of the Building or other portion of
the Project, or real estate agent or broker, either directly or indirectly, or (ii) post or place on any website or other form
of media, directly or indirectly, any of the terms and conditions of the Lease or opine or critique Landlord’s management
ownership abilities and skills.

 

[SIGNATURES APPEAR ON NEXT PAGE]

 

    	 	6	 

     

    

 

IN WITNESS WHEREOF,
the parties hereto have executed this First Amendment under seal as of the day and year first above written.

 

	 	TENANT:
	 	 
	 	GENVEC, INC.,
	 	a Delaware corporation
	 	 
	 	By:	/s/ Douglas J. Swirsky	(SEAL)
	 	Its:	President + CEO	 

 

	 	LANDLORD:
	 	 
	 	ARE-MARYLAND NO. 30, LLC,
	 	a Maryland limited liability company

 

	 	By:	ARE-Maryland No. 29, LLC,
	 	a Maryland limited liability company,
	 	as its sole member

 

	 	By:	Alexandria Real Estate Equities, L.P.,
	 	a Delaware limited partnership,
	 	as its sole member

 

	 	By:	ARE-QRS CORP.,
	 	a Maryland corporation,
	 	general partner

 

	 	By:	/s/ Jennifer Banks 	(SEAL)
	 	Name:	Jennifer Banks	 
	 	Title:	EVP, General Counsel	 

 

    	 	7	 

     

    

 

EXHIBIT A

ORIGINAL PREMISES AND EXPANSION PREMISES

 

(See attached)

 

     

     

    

 

 

 

    	 	A-1	 

     

    

 

EXHIBIT B

ACKNOWLEDGMENT OF EXPANSION PREMISES COMMENCEMENT DATE

 

This ACKNOWLEDGMENT
OF EXPANSION PREMISES COMMENCEMENT DATE is made as of this ____ day of ______________, 201_, between ARE-MARYLAND NO. 30,
LLC, a Delaware limited liability company (“Landlord”), and GENVEC, INC., a Delaware corporation
(“Tenant”), and is attached to and made a part of the First Amendment to Lease Agreement dated as of December_,
2014 (“First Amendment”), by and between Landlord and Tenant. Any initially capitalized terms used but not defined
herein shall have the meanings given them in the First Amendment.

 

Landlord and Tenant
hereby acknowledge and agree that the Expansion Premises Commencement Date is December , 2014, the Expansion Premises Rent Commencement
Date is January 1, 2015 (subject to the Rental Abatement set forth in the First Amendment), and the expiration date of the Base
Term of the Lease shall be midnight on October 31, 2019. In case of a conflict between the terms of the First Amendment and the
terms of this Acknowledgement of Expansion Premises Commencement Date, this Acknowledgement of Expansion Premises Commencement
Date shall control for all purposes.

 

IN WITNESS WHEREOF,
Landlord and Tenant have executed this ACKNOWLEDGMENT OF EXPANSION PREMISES COMMENCEMENT DATE under seal to be effective on the
date first above written.

 

	 	TENANT:
	 	 
	 	GENVEC, INC.,
	 	a Delaware corporation
	 	 
	 	By:	 	(SEAL)
	 	Its:	 	 

 

	 	LANDLORD:
	 	 
	 	ARE-MARYLAND NO. 30, LLC,
	 	a Maryland limited liability company
	 	 
	 	By:	ARE-Maryland No. 29, LLC,
	 	a Maryland limited liability company,
	 	as its sole member

 

	 	By:	Alexandria Real Estate Equities, L.P.,
	 	a Delaware limited partnership,
	 	as its sole member

 

    	 	B-1	 

     

    

 

	 	By:	ARE-QRS CORP.,
	 	 	a Maryland corporation,
	 	 	general partner

 

	 
	 	By:		(SEAL)
	 	Name:	 	 
	 	Title:	 	 

 

    	 	B-2

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