Document:

Exhibit 10.3

 

Execution Version

 

SECURITY AND PLEDGE AGREEMENT
FOR OBLIGATIONS OF ICA-T

 

SECURITY
AND PLEDGE AGREEMENT FOR OBLIGATIONS OF ICA-T, dated as of May 15, 2017 (this “Agreement”), made by Icagen,
Inc., a Delaware corporation with offices located at 4222 Emperor Blvd., Suite 350, Research Triangle Park, Durham, NC, 27703
(the “Parent”), Icagen-T, Inc., a Delaware corporation and a wholly-owned Subsidiary of the Parent with offices
located at 2090 E. Innovation Park Drive, Oro Valley, Arizona 85755 (“ICA-T”) and each of the undersigned direct
and indirect Domestic Subsidiaries (as defined below) from time to time (together with ICA-T and the Parent, collectively, the
“Grantors” and each a “Grantor”), in favor of GPB Debt Holdings II, LLC (in its capacity
as collateral agent for itself as purchaser of the Notes (as defined below) and each other Person who may become a Noteholder
(as defined below), the “Collateral Agent;” and in its capacity as the purchaser of the Notes, the “Buyer”),
pursuant to the Securities Purchase Agreement, dated as of May 15, 2017 (as amended, modified, supplemented, extended, renewed,
restated or replaced from time to time, the “Securities Purchase Agreement”).

 

W I T N E S S E T H:

 

WHEREAS, the
Parent, ICA-T and the Buyer are parties to the Securities Purchase Agreement, pursuant to which, among other items (i) ICA-T issued
and sold an $8,000,000 aggregate principal amount senior secured convertible note of ICA-T (as such may be amended, modified,
supplemented, extended, renewed, restated or replaced from time to time (the “ICA-T Note”), and (ii) the Parent
issued and sold, among other securities, a $2,000,000 aggregate principal amount senior secured convertible note of the Parent
(as such may be amended, modified, supplemented, extended, renewed, restated or replaced from time to time (the “Parent
Note” and together with the ICA-T Note, collectively, the “Notes), to the Buyer;”

 

WHEREAS, the
Parent and certain other Grantors from time to time (other than ICA-T) (each a “Guarantor” and collectively,
the “Guarantors”) may execute and deliver one or more guaranties including, but not limited to, that Guaranty
of Obligations of ICA-T (as defined below) in form and substance acceptable to and in favor of the Collateral Agent, for the benefit
of itself as a Noteholder and any other Noteholder with respect to all of (i) ICA-T’s obligations under the ICA-T Note,
the Securities Purchase Agreement and the other Transaction Documents (as defined in the Securities Purchase Agreement), and (ii)
the Parent’s obligations under the ICA-T Note;

 

WHEREAS, it
is a condition precedent to the Buyer’s obligation to purchase the ICA-T Note, (and the Parent Note and the Parent Warrant)
issued pursuant to the Securities Purchase Agreement, that the Grantors (including ICA-T) shall have executed and delivered to
the Collateral Agent this Agreement providing for the grant to the Collateral Agent, for the benefit of itself as a Noteholder
and any other Noteholder, of a valid, enforceable, and perfected security interest in all personal property of each Grantor to
secure all of (i) ICA-T’s obligations under the Transaction Documents, (ii) the Grantors’ (other than ICA-T) obligations
under the Guaranty of Obligations of ICA-T, and (iii) the Parent’s obligations under the ICA-T Note; and

 

WHEREAS, each
Grantor has determined that the execution, delivery and performance of this Agreement directly and/or indirectly benefits, and
is in the best interest of, such Grantor;

 

     

     

    

 

NOW, THEREFORE,
in consideration of the premises and the agreements herein and such other consideration which the parties hereto recognize and
acknowledge the sufficiency of and in order to induce the Buyer to perform its obligations under the Securities Purchase Agreement,
each Grantor agrees with the Collateral Agent, for the benefit of the Collateral Agent and the Noteholders, as follows:

 

SECTION
1. Definitions.

 

(a)       Reference
is hereby made to the Securities Purchase Agreement and the Notes for a statement of the terms thereof. All terms used in this
Agreement and the recitals hereto which are defined in the Securities Purchase Agreement, the Notes or in the Code (as defined
below), and which are not otherwise defined herein shall have the same meanings herein as set forth therein; provided that
terms used herein which are defined in the Code on the date hereof shall continue to have the same meaning notwithstanding any
replacement or amendment of the Code except as the Collateral Agent may otherwise determine.

 

(b)       The
following terms shall have the respective meanings provided for in the Code: “Accounts” “Account Debtor”,
“Cash Proceeds”, “Certificate of Title”, “Chattel Paper”, “Commercial Tort Claim”,
“Commodity Account”, “Commodity Contracts”, “Deposit Account”, “Documents”, “Electronic
Chattel Paper”, “Equipment”, “Fixtures”, “General Intangibles”, “Goods”,
“Instruments”, “Inventory”, “Investment Property”, “Letter-of-Credit Rights”,
“Payment Intangibles”, “Proceeds”, “Promissory Notes”, “Security”, “Record”,
“Security Account”, “Software”, and “Supporting Obligations”.

 

(c)       As
used in this Agreement, the following terms shall have the respective meanings indicated below, such meanings to be applicable
equally to both the singular and plural forms of such terms:

 

“Affiliate”
of any Person means any other Person which, directly or indirectly, controls or is controlled by or is under common control with
such Person and any officer or director of such Person. A Person shall be deemed to be “controlled by” any other Person
if such Person possesses, directly or indirectly, power to vote 10% or more of the securities (on a fully diluted basis) having
ordinary voting power for the election of directors or managers or power to direct or cause the direction of the management and
policies of such Person, whether by contract or otherwise.

 

“Bankruptcy
Code” means Chapter 11 of Title 11 of the United States Code, 11 U.S.C §§ 101 et seq. (or other applicable
bankruptcy, insolvency or similar laws).

 

“Business
Day” means any day other than Saturday, Sunday or other day on which commercial banks in New York City are authorized
or required by law to remain closed.

 

“Buyer”
shall have the meaning set forth in the recitals hereto.

 

“Capital
Stock” means (i) with respect to any Person that is a corporation, any and all shares, interests, participations or
other equivalents (however designated and whether or not voting) of corporate stock (including, without limitation, any warrants,
options, rights or other securities exercisable or convertible into equity interests or securities of such Person), and (ii) with
respect to any Person that is not a corporation, any and all partnership, membership or other equity interests of such Person.

 

    	 	2	 

     

    

 

“Closing
Date” means the date of the sale by (i) ICA-T of the ICA-T Note, and (ii) the Parent of the Parent Note and the Parent
Warrant to the Buyer pursuant to the terms of the Securities Purchase Agreement.

 

“Code”
means Articles 8 or 9 of the Uniform Commercial Code as in effect from time to time in the State of New York; provided
that, if perfection or the effect of perfection or non-perfection or the priority of any security interest in any Collateral is
governed by the Uniform Commercial Code as in effect in a jurisdiction other than the State of New York, “Code” means
the Uniform Commercial Code as in effect from time to time in such other jurisdiction for purposes of the provisions hereof relating
to such perfection, effect of perfection or non-perfection or priority.

 

“Collateral”
shall have the meaning set forth in Section 2(a) of this Agreement.

 

“Collateral
Agent” shall have the meaning set forth in the preamble hereto.

 

“Controlled
Account Agreement” means a deposit account control agreement or securities account control agreement with respect to
a Pledged Account, in form and substance satisfactory to the Collateral Agent, as the same may be amended, modified, supplemented,
extended, renewed, restated or replaced from time to time.

 

“Controlled
Accounts” means the Deposit Accounts, Commodity Accounts, Securities Accounts, and/or Foreign Currency Controlled Account
of the Grantors listed on Schedule I attached hereto.

 

“Copyright
Licenses” means all licenses, contracts or other agreements, whether written or oral, naming any Grantor as licensee
or licensor and providing for the grant of any right to use or sell any works covered by any Copyright (including, without limitation,
all Copyright Licenses set forth in Schedule II hereto).

 

“Copyrights”
means all domestic and foreign copyrights, whether registered or not, including, without limitation, all copyright rights throughout
the universe (whether now or hereafter arising) in any and all media (whether now or hereafter developed), in and to all original
works of authorship fixed in any tangible medium of expression, acquired or used by any Grantor (including, without limitation,
all copyrights described in Schedule II hereto), all applications, registrations and recordings thereof (including, without
limitation, applications, registrations and recordings in the United States Copyright Office or in any similar office or agency
of the United States or any other country or any political subdivision thereof), and all reissues, divisions, continuations, continuations
in part and extensions or renewals thereof.

 

“Domestic
Subsidiary” means any Subsidiary other than a Foreign Subsidiary.

 

“Event
of Default” shall have the meaning set forth in Section 4(a) of the ICA-T Note.

 

    	 	3	 

     

    

 

“Excluded
Collateral” means (A) the voting Capital Stock of any Foreign Subsidiary to the extent that (i) such Capital Stock represents
more than 65% of the issued and outstanding voting Capital Stock of such Foreign Subsidiary and (ii) to the extent the pledge
thereof is prohibited by the laws of such Foreign Subsidiary’s Organization or pledging more than 65% of the total outstanding
voting Capital Stock of such Foreign Subsidiary would result in a material adverse tax consequence to a Grantor, (B) accounts
receivable and/or Inventory of each Grantor, but only if and to the extent as of any time of determination any such Grantor’s
accounts receivable and/or Inventory is being factored pursuant to an existing accounts receivable and/or Inventory financing
arrangement between the provider of such financing and such Grantor, provided at all times commencing on the Closing Date (as
defined in the Securities Purchase Agreement) that a Grantor’s accounts receivable and/or Inventory does not constitute
Excluded Collateral pursuant to (B) of this definition of Excluded Collateral, such shall constitute Collateral and the Collateral
Agent for the benefit of itself as a Noteholder and any other Noteholders shall have a senior secured security interest in and
a valid, enforceable perfected senior priority Lien on such Grantor’s accounts receivable and/or Inventory and the Parent
and each Grantor shall take at any time and from time to time any and all action necessary and/or as reasonably requested by the
Collateral Agent to effectuate the same including, but not limited to, providing an opinion of legal counsel to the Parent relating
to the above in form and substance satisfactory to the Collateral Agent, and (C) the Capital Stock of ICA-T; provided, the Capital
Stock of ICA-T shall not be considered Excluded Collateral and shall constitute Collateral and “Pledged Equity”
and ICA-T shall be a Pledged Entity commencing on the first calendar day following the date that the Master Services Agreement
dated July 15, 2016 by and between Sanofi US Services, Inc. (“Sanofi”) and ICA-T (as amended, restated and/or
otherwise modified, the “MSA”) shall not prohibit the Capital Stock of ICA-T from being pledged as Collateral
(the “Restriction End Date”) and in connection therewith, ICA-T and the Parent shall take any and all such
actions necessary and/or requested by the Collateral Agent to satisfy the Collateral Agent that such and the following has been
effectuated and that the Collateral Agent for the benefit of itself as a Noteholder and any other Noteholders has a senior secured
security interest in and a perfected senior priority Lien on the Capital Stock of ICA-T and that the Capital Stock of ICA-T is
not directly and/or indirectly subject to any security interest and/or Lien of Sanofi and/or any other Person (except the Collateral
Agent for the benefit of itself as a Noteholder and the holder of the Parent Note and any other Noteholder and/or other holder
of a Parent Note) including, but not limited to, providing an opinion of legal counsel to the Parent relating to the above in
form and substance satisfactory to the Collateral Agent (the “ICA-T Capital Stock Actions”).

 

“Foreign
Currency Controlled Accounts” means any Controlled Account of the Parent or its Subsidiaries holding non-United States
dollar deposits.

 

“Foreign
Subsidiary” means any Subsidiary of a Grantor organized under the laws of a jurisdiction other than the United States,
any of the states thereof, Puerto Rico or the District of Columbia.

 

“GAAP”
means U.S. generally accepted accounting principles consistently applied.

 

“Governmental
Authority” means any nation or government, any Federal, state, city, town, municipality, county, local, foreign or other
political subdivision thereof or thereto and any department, commission, board, bureau, instrumentality, agency or other entity
exercising executive, legislative, judicial, taxing, regulatory or administrative powers or functions of or pertaining to government.

 

    	 	4	 

     

    

 

“Guaranteed
Obligations of ICA-T” shall have the meaning set forth in Section 2 of the Guaranty of Obligations of ICA-T.

 

“Guarantor”
or “Guarantors” shall have the meaning set forth in the recitals hereto.

 

“Guaranty”
or “Guaranties” shall mean any additional guaranties required to be entered into pursuant to the Transaction
documents with respect to the ICA-T Note.

 

“Guaranty
of Obligations of ICA-T” shall mean that Guaranty of Obligations of ICA-T dated the date hereof made by the Grantors
(other than ICA-T) and any future grantors.

 

“ICA-T
Note” shall have the meaning set forth in the recitals hereto.

 

“Insolvency
Proceeding” means any proceeding commenced by or against any Person under any provision of the Bankruptcy Code or under
any other bankruptcy or insolvency law, assignments for the benefit of creditors, formal or informal moratoria, compositions,
or extensions generally with creditors, or proceedings seeking reorganization, arrangement, or other similar relief.

 

“Intellectual
Property” means, collectively, the Copyrights, Trademarks and Patents.

 

“Intellectual
Property Security Agreement” means the Intellectual Property Security Agreement required to be delivered pursuant to
Section 5(h)(i) of this Agreement, in the form attached hereto as Exhibit A.

 

“Licenses”
means, collectively, the Copyright Licenses, the Trademark Licenses and the Patent Licenses, provided any such License does not
contain a provision expressly prohibiting the pledge of such License.

 

“Lien”
means any mortgage, lien, pledge, charge, security interest, adverse claim or other encumbrance upon or in any property or assets.

 

“Noteholder”
means, at any time, the holders of all or any portion of the ICA-T Note at such time.

 

“Obligations”
shall have the meaning set forth in Section 3 of this Agreement.

 

“Paid
in Full” or “Payment in Full” means the indefeasible payment in full (including by way of redemption)
of all Obligations in cash (and/or through the issuance of shares of Parent Common Stock (as defined in the ICA-T Note), by the
ICA-T, Parent or a Subsidiary but only if and to the extent permitted by the ICA-T Note and the other Transaction Documents).

 

“Parent”
shall have the meaning set forth in the preamble hereto.

 

    	 	5	 

     

    

 

“Patent
Licenses” means all licenses, contracts or other agreements, whether written or oral, naming any Grantor as licensee
or licensor and providing for the grant of any right to manufacture, use or sell any invention covered by any Patent (including,
without limitation, all Patent Licenses set forth in Schedule III hereto).

 

“Patents”
means all domestic and foreign letters patent, design patents, utility patents, industrial designs, inventions, trade secrets,
ideas, concepts, methods, techniques, processes, proprietary information, technology, know-how, formulae, rights of publicity
and other general intangibles of like nature, now existing or hereafter acquired (including, without limitation, all domestic
and foreign letters patent, design patents, utility patents, industrial designs, inventions, trade secrets, ideas, concepts, methods,
techniques, processes, proprietary information, technology, know-how and formulae described in Schedule III hereto), all
applications, registrations and recordings thereof (including, without limitation, applications, registrations and recordings
in the United States Patent and Trademark Office, or in any similar office or agency of the United States or any other country
or any political subdivision thereof), and all reissues, reexaminations, divisions, continuations, continuations in part and extensions
or renewals thereof.

 

“Perfection
Requirement” or “Perfection Requirements” shall have the meaning set forth in Section 4(j) of this
Agreement.

 

“Person”
means an individual, corporation, limited liability Parent, partnership, association, joint-stock Parent, trust, unincorporated
organization, joint venture or other enterprise or entity or Governmental Authority.

 

“Pledged
Accounts” means all of each Grantor’s right, title and interest in all of its Deposit Accounts, Commodity Accounts
and Securities Accounts (in all cases, including, without limitation, all Controlled Accounts and Foreign Currency Control Accounts).

 

“Pledged
Entity” means, each Person listed from time to time on Schedule IV hereto as a “Pledged Entity,”
together with each other Person, any right in or interest in or to all or a portion of whose Capital Stock is acquired or otherwise
owned by a Grantor after the date hereof.

 

“Pledged
Equity” means all of each Grantor’s right, title and interest in and to all of the Securities and Capital Stock
now or hereafter owned by such Grantor, regardless of class or designation, including all substitutions therefor and replacements
thereof, all proceeds thereof and all rights relating thereto, also including any certificates representing the Securities and/or
Capital Stock, the right to receive any certificates representing any of the Securities and/or Capital Stock, all warrants, options,
share appreciation rights and other rights, contractual or otherwise, in respect thereof, and the right to receive dividends,
distributions of income, profits, surplus, or other compensation by way of income or liquidating distributions, in cash or in
kind, and cash, instruments, and other property from time to time received, receivable, or otherwise distributed in respect of
or in addition to, in substitution of, on account of, or in exchange for any or all of the foregoing; provided, however,
that the term Pledged Equity shall include all ICA-T Capital Stock commencing on the Restriction End Date and the Parent, ICA-T
and each other Grantor shall take all ICA-T Capital Stock Actions.

 

    	 	6	 

     

    

 

“Pledged
Operating Agreements” means all of each Grantor’s rights, powers and remedies under the limited liability Parent
operating agreements of each of the Pledged Entities that are limited liability companies, as may be amended, modified, supplemented,
extended, renewed, restated or replaced from time to time.

 

“Pledged
Partnership Agreements” means all of each Grantor’s rights, powers, and remedies under the partnership agreements
of each of the Pledged Entities that are partnerships, as may be amended, modified, supplemented, extended, renewed, restated
or replaced from time to time.

 

“Securities
Purchase Agreement” shall have the meaning set forth in the recitals hereto.

 

“Subsidiary”
means any Person in which a Grantor directly or indirectly (i) owns a majority of the outstanding Capital Stock, voting stock
or holds a majority of any equity or similar interest of such Person or (ii) controls or operates a substantial portion of the
business, operations or administration of such Person, and all of the foregoing, collectively, “Subsidiaries”.

 

“Trademark
Licenses” means all licenses, contracts or other agreements, whether written or oral, naming any Grantor as licensor
or licensee and providing for the grant of any right concerning any Trademark, together with any goodwill connected with and symbolized
by any such licenses, contracts or agreements and the right to prepare for sale or lease and sell or lease any and all Inventory
now or hereafter owned by any Grantor and now or hereafter covered by such licenses, contracts or agreements (including, without
limitation, all Trademark Licenses described in Schedule V hereto).

 

“Trademarks”
means all domestic and foreign trademarks, service marks, collective marks, certification marks, trade names, business names,
d/b/a’s, assumed names, Internet domain names, trade styles, designs, logos and other source or business identifiers and
all general intangibles of like nature, now or hereafter owned, adopted, acquired or used by any Grantor (including, without limitation,
all domestic and foreign trademarks, service marks, collective marks, certification marks, trade names, business names, d/b/a’s,
assumed names, Internet domain names, trade styles, designs, logos and other source or business identifiers described in Schedule
V(a) hereto), all applications, registrations and recordings thereof (including, without limitation, applications, registrations
and recordings in the United States Patent and Trademark Office or in any similar office or agency of the United States, any state
thereof or any other country or any political subdivision thereof), and all reissues, extensions or renewals thereof, together
with all goodwill of the business symbolized by such marks and all customer lists, formulae and other Records of any Grantor relating
to the distribution of products and services in connection with which any of such marks are used.

 

SECTION 2. Grant
of Security Interest.

 

(a)       As
collateral security for the due and punctual payment and performance of all of the Obligations, as and when due, each Grantor
hereby pledges, assigns and grants to the Collateral Agent, for the benefit of itself as a Noteholder itself and for the benefit
of any other Noteholders, a continuing security interest in, all personal property and assets of such Grantor, wherever located
and whether now or hereafter existing and whether now owned or hereafter acquired, of every kind, nature and description, whether
tangible or intangible (collectively, the “Collateral”), including, without limitation, the following:

 

(i)       
All Accounts (but with regard to accounts receivable, subject to the provisions of Section (B) of the definition of Excluded Collateral);

 

    	 	7	 

     

    

 

(ii)       all
Chattel Paper (whether tangible or Electronic Chattel Paper) having a value in excess of $25,000;

 

(iii)      all
Commercial Tort Claims having a value in excess of $25,000, including, without limitation, those specified on Schedule VI
hereto;

 

(iv)      all
Documents;

 

(v)       all
Equipment;

 

(vi)      all
Fixtures;

 

(vii)     all
General Intangibles (including, without limitation, all Payment Intangibles);

 

(viii)    all
Goods;

 

(ix)      all
Inventory (subject to the provisions of Section (B) of the definition of Excluded Collateral);

 

(x)       all
Instruments (including, without limitation, all Promissory Notes and each certificated Security);

 

(xi)      all
Investment Property (and, regardless of whether classified as Investment Property under the Code, all Pledged Equity, Pledged
Operating Agreements and Pledged Partnership Agreements);

 

(xii)     all
Intellectual Property and Licenses;

 

(xiii)    all
Letters of Credit and Letter-of-Credit Rights;

 

(xiv)    all
Pledged Accounts, all cash and other property from time to time deposited therein, and all monies and property in the possession
or under the control of the Collateral Agent or any Noteholder or any Affiliate, representative, agent or correspondent of the
Collateral Agent or any such Noteholder;

 

(xv)     all
Supporting Obligations;

 

    	 	8	 

     

    

 

(xvi)     all
other tangible and intangible personal property of each Grantor (whether or not subject to the Code), including, without limitation,
all those relating to ICA-T’s compound library pursuant to which a security interest can be granted upon, all  cell
line and plasmid repositories and related items, all Deposit and other accounts and all cash and all investments therein, all
proceeds, products, offspring, accessions, rents, profits, income, benefits, substitutions and replacements of and to any of the
property of any Grantor described in the preceding clauses of this Section 2(a) (including, without limitation, any proceeds
of insurance thereon and all causes of action, claims and warranties now or hereafter held by each Grantor in respect of any of
the items listed above), and all books, correspondence, files and other Records, including, without limitation, all tapes, desks,
cards, Software, data and computer programs in the possession or under the control of any Grantor or any other Person from time
to time acting for any Grantor, in each case, to the extent of such Grantor’s rights therein, that at any time evidence
or contain information relating to any of the property described in the preceding clauses of this Section 2(a) or are otherwise
necessary or helpful in the collection or realization thereof; and

 

(xvii)    all
Proceeds, including all Cash Proceeds and Noncash Proceeds, and products of any and all of the foregoing Collateral;

 

in each case howsoever any Grantor’s
interest therein may arise or appear (whether by ownership, security interest, claim or otherwise).

 

(b)       Notwithstanding
anything herein to the contrary, the term “Collateral” shall not include any Excluded Collateral.

 

(c)       Except
for Permitted Liens, each Grantor agrees not to further encumber, or permit any other Lien to exist that encumbers, any of its
Copyrights, Copyright applications, Copyright registrations and like protections in each work of authorship and derivative work,
whether published or unpublished, any Licenses other than by the parties to the License, Patents, Patent applications and like
protections, including improvements, divisions, continuations, renewals, reissues, extensions, and continuations-in-part of the
same, Trademarks, service marks and, to the extent permitted under applicable law, any applications therefor, whether registered
or not, and the goodwill of the business of such Grantor connected with and symbolized thereby, know-how, operating manuals, trade
secret rights, rights to unpatented inventions, and any claims for damage by way of any past, present, or future infringement
of any of the foregoing, in each case without the Collateral Agent’s prior written consent (which consent may be withheld
or given in the Collateral Agent’s sole discretion).

 

(d)       The
Grantors agree that the pledge of the shares of Capital Stock acquired by a Grantor of any and all Persons now or hereafter existing
who is a Foreign Subsidiary may be supplemented by one or more separate pledge agreements, deeds of pledge, share charges or other
similar agreements or instruments, executed and delivered by the relevant Grantors in favor of the Collateral Agent, which pledge
agreements will provide for the pledge of such shares of Capital Stock in accordance with the laws of the applicable foreign jurisdiction
but in no event shall Excluded Collateral be pledged. With respect to such shares of Capital Stock, the Collateral Agent may,
at any time and from time to time, in its sole discretion, take such actions in such foreign jurisdictions that will result in
the perfection of the Lien created in such shares of Capital Stock.

 

(e)       In
addition, to secure the prompt and complete payment, performance and observance of the Obligations and in order to induce the
Buyer as aforesaid, each Grantor hereby grants to the Collateral Agent, for itself and for the ratable benefit of the Noteholders,
a right of set-off against the property of such Grantor held by the Collateral Agent, for itself and for the ratable benefit of
the Noteholders, consisting of property described above in Section 2(a) now or hereafter in the possession or custody of
or in transit to the Collateral Agent, for any purpose, including safekeeping, collection or pledge, for the account of such Grantor,
or as to which such Grantor may have any right or power; provided that such right shall only to be exercised after an Event of
Default has occurred and is continuing.

 

    	 	9	 

     

    

 

SECTION 3. Security
for Obligations. The security interest created hereby in the Collateral constitutes continuing collateral security for all
of the following obligations, whether direct or indirect, absolute or contingent, and whether now existing or hereafter incurred
(collectively, the “Obligations”):

 

(a)       (i)
all payments by ICA-T as and when due and payable (by scheduled maturity, required prepayment, redemption, acceleration, demand
or otherwise), of all amounts from time to time owing by it in respect of the Securities Purchase Agreement, this Agreement, the
ICA-T Note and the other Transaction Documents to which ICA-T is a party, (ii) all payments by the Parent as and when due and
payable (by scheduled maturity, required prepayment, redemption, acceleration, demand or otherwise), of all amounts from time
to time owing by the Parent in respect of the ICA-T Note and/or any other obligations of ICA-T pursuant to any other Transaction
Document and (iii) in the case of the Guarantors, the payment by such Guarantors, as and when due and payable of all Guaranteed
Obligations of ICA-T under the Guaranty of Obligations of ICA-T, including, without limitation, in all cases set forth in (i)
– (iii) above, (A) all principal of, interest, redemption amounts, Late Charges (as defined in the ICA-T Note) and other
amounts on the ICA-T Note and the other Transaction Documents to which ICA-T is a party (including, without limitation, all interest,
redemption amounts, Late Charges and other amounts that accrue after the commencement of any Insolvency Proceeding of any Grantor,
whether or not the payment of such interest is enforceable or is allowable in such Insolvency Proceeding), and (B) all fees, interest,
Late Charges, premiums, penalties, contract causes of action, costs, commissions, expense reimbursements, indemnifications and
all other amounts due or to become due under this Agreement or any of the Transaction Documents; and

 

(b)       the
due performance and observance by each Grantor of all of its other obligations from time to time existing in respect of any of
the Transaction Documents, including without limitation, with respect to any conversion or redemption rights of the Noteholders
under the ICA-T Note.

 

SECTION 4. Representations
and Warranties. Each Grantor represents and warrants as follows:

 

(a)       Schedule
VII hereto sets forth (i) the exact legal name of each Grantor, and (ii) the state of incorporation, organization or formation
and the organizational identification number of each Grantor in such state. The information set forth in Schedule VII hereto
with respect to such Grantor is true and accurate in all respects. Such Grantor has not previously changed its name (or operated
under any other name), jurisdiction of organization or organizational identification number from those set forth in Schedule
VII hereto except as disclosed in Schedule VII hereto.

 

    	 	10	 

     

    

 

(b)       There
is no pending or, to its knowledge, written notice threatening any action, suit, proceeding or claim affecting any Grantor before
any Governmental Authority or any arbitrator, or any order, judgment or award issued by any Governmental Authority or arbitrator,
in each case, that may adversely affect the grant by any Grantor, or the perfection, of the security interest purported to be
created hereby in the Collateral, or the exercise by the Collateral Agent of any of its rights or remedies hereunder.

 

(c)       All
Federal, state and local tax returns and other reports required by applicable law to be filed by any Grantor have been filed,
or extensions have been obtained, and all taxes, assessments and other governmental charges imposed upon any Grantor or any property
of any Grantor (including, without limitation, all federal income and social security taxes on employees’ wages) and which
have become due and payable on or prior to the date hereof have been paid, except to the extent contested in good faith by proper
proceedings which stay the imposition of any penalty, fine or Lien resulting from the non-payment thereof and with respect to
which adequate reserves have been set aside for the payment thereof in accordance with GAAP.

 

(d)       All
Equipment, Fixtures, Goods and Inventory of each Grantor now existing are, and all Equipment, Fixtures, Goods and Inventory of
each Grantor hereafter existing will be, located and/or based at the addresses specified therefor in Schedule VIII hereto,
except that each Grantor will give the Collateral Agent written notice of any change in the location of any such Collateral within
20 days of such change, other than to locations set forth on Schedule VIII hereto (and with respect to which the Collateral
Agent has filed financing statements and otherwise fully perfected its Liens thereon). Each Grantor’s principal place of
business and chief executive office, the place where each Grantor keeps its Records concerning the Collateral and all located
at the addresses specified therefor in Schedule VIII hereto. None of the Accounts is or will be evidenced by Promissory
Notes or other Instruments.

 

(e)       Set
forth in Schedule IX hereto is a complete and accurate list, as of the date of this Agreement, of (i) each Promissory Note,
Security and other Instrument owned by each Grantor, (ii) each Pledged Account of each Grantor, together with the name and address
of each institution at which each such Pledged Account is maintained, the account number for each such Pledged Account and a description
of the purpose of each such Pledged Account and (iii) the name of each Foreign Currency Controlled Account, together with the
name and address of each institution at which each such Foreign Currency Controlled Account is maintained and the amount of cash
or cash equivalents held in each such Foreign Currency Controlled Account. Set forth in Schedule IX hereto is a complete
and correct list of each trade name used by each Grantor and the name of, and each trade name used by, each Person from which
each Grantor has acquired any substantial part of the Collateral.

 

    	 	11	 

     

    

 

(f)       Each
Grantor has delivered to the Collateral Agent complete and correct copies of each License described in Schedule X hereto,
including all schedules and exhibits thereto, which represent all of the Licenses of the Grantors existing on the date of this
Agreement. Each such License sets forth the entire agreement and understanding of the parties thereto relating to the subject
matter thereof, and there are no other agreements, arrangements or understandings, written or oral, relating to the matters covered
thereby or the rights of such Grantor or any of its Affiliates in respect thereof. Each material License now existing is, and
any material License entered into in the future will be, the legal, valid and binding obligation of the parties thereto, enforceable
against such parties in accordance with its terms except as such enforceability may be limited by applicable bankruptcy, insolvency,
reorganization, and similar laws of general application relating to or affecting the rights and remedies of creditors and by general
principles of equity. No default under any material License by any such party has occurred, nor does any defense, offset, deduction
or counterclaim exist thereunder in favor of any such party.

 

(g)       Each
Grantor owns and controls, or otherwise possesses adequate rights to use, all of its Intellectual Property. Schedule XI
hereto sets forth a true and complete list of all Intellectual Property and Licenses owned or used by each Grantor as of the date
hereof, and applications for grant or registration of Intellectual Property. To the knowledge of each Grantor, all such Intellectual
Property of such Grantor is subsisting and in full force and effect, has not been adjudged invalid or unenforceable, and has not
been abandoned in whole or in part. Except as set forth in Schedule XI, no such Intellectual Property is the subject of
any licensing or franchising agreement. Except as set forth in Schedule XI, no Grantor has any knowledge of any infringement
upon or conflict with the Patent, Trademark, Copyright, trade secret rights of others and, each Grantor is not now knowingly infringing
or knowingly in conflict with any Patent, Trademark, Copyright, trade secret or similar rights of others, and to the knowledge
of each Grantor, no other Person is now infringing or in conflict in any material respect with any such properties, assets and
rights owned or used by each Grantor. No Grantor has received any notice that it is violating or has violated the Trademarks,
Patents, Copyrights, inventions, trade secrets, proprietary information and technology, know-how, formulae, rights of publicity
or other intellectual property rights of any third party.

 

(h)       Each
Grantor is and will be at all times the sole and exclusive owner of the Collateral pledged by such Grantor hereunder free and
clear of any Liens, except for Permitted Liens thereon. No effective financing statement or other instrument similar in effect
covering all or any part of the Collateral is on file in any recording or filing office except such as (i) may have been filed
in favor of the Collateral Agent and/or the Noteholders relating to this Agreement or the other Transaction Documents, and (ii)
are securing Permitted Liens as of the date hereof and disclosed on Schedule XII hereto.

 

(i)        The
exercise by the Collateral Agent of any of its rights and remedies hereunder will not contravene any law or any contractual restriction
binding on or otherwise affecting each Grantor or any of its properties and will not result in or require the creation of any
Lien, upon or with respect to any of its properties.

 

    	 	12	 

     

    

 

(j)       No
authorization or approval or other action by, and no notice to or filing with, any Governmental Authority, is required for (i)
the grant by each Grantor, or the perfection, of the security interest purported to be created hereby in the Collateral, or (ii)
the exercise by the Collateral Agent of any of its rights and remedies hereunder, except for (A) the filing under the Code as
in effect in the applicable jurisdiction of the financing statements described in Schedule XII hereto, all of which financing
statements have been duly filed and are in full force and effect, (B) with respect to all Pledged Accounts, and all cash and other
property from time to time deposited therein, the execution of a Controlled Account Agreement with the depository or other institution
with which the applicable Pledged Accounts are maintained, as provided in Section 5(h)(i), (C) with respect to Commodity
Contracts, the execution of a control agreement with the commodity intermediary with which such Commodity Contract is carried,
as provided in Section 5(h)(i), (D) with respect to the perfection of the security interest created hereby in the United
States Intellectual Property and Licenses, the recording of the appropriate Intellectual Property Security Agreement in the United
States Patent and Trademark Office or the United States Copyright Office, as applicable (E) with respect to the perfection of
the security interest created hereby in any Letter-of-Credit Rights, the consent of the issuer of the applicable letter of credit
to the assignment of proceeds as provided in the Code as in effect in the applicable jurisdiction, (G) with respect to Investment
Property constituting uncertificated securities, the applicable Grantor causing the issuer thereof either (i) to register the
Collateral Agent as the registered owner of such securities or (ii) to agree in an authenticated record with such Grantor and
the Collateral Agent that such issuer will comply with instructions with respect to such securities originated by the Collateral
Agent without further consent of such Grantor, such authenticated record to be in form and substance satisfactory to the Collateral
Agent, (H) with respect to Investment Property constituting certificated securities or instruments, such items to be delivered
to and held by or on behalf of the Collateral Agent pursuant hereto in suitable form for transfer by delivery or accompanied by
duly executed instruments of transfer or assignment in blank, all in form and substance satisfactory to the Collateral Agent,
(I) with respect to any action that may be necessary to obtain control of Collateral constituting Commodity Contracts, Electronic
Chattel Paper or Letter of Credit Rights, the taking of such actions, and (J) the Collateral Agent having possession of all Documents,
Chattel Paper, Instruments and cash constituting Collateral (subclauses (A) through (J) each a “Perfection Requirement”
and collectively, the “Perfection Requirements”).

 

(k)       This
Agreement creates in favor of the Collateral Agent a legal, valid and enforceable security interest in the Collateral, as security
for the Obligations. The performance of the Perfection Requirements results in the perfection of such security interest in the
Collateral. Such security interest is (or in the case of Collateral in which each Grantor obtains rights after the date hereof,
will be), subject only to Permitted Liens and the Perfection Requirements, a first priority, valid, enforceable and perfected
security interests in all personal property of each Grantor (other than Excluded Collateral). Such recordings and filings and
all other action necessary to perfect and protect such security interest have been duly taken (and, in the case of Collateral
in which any Grantor obtains rights after the date hereof, will be duly taken), except for the Collateral Agent’s having
possession of all Documents, Chattel Paper, Instruments and cash constituting Collateral after the date hereof and the other actions,
filings and recordations described above, including the Perfection Requirements.

 

(l)        As
of the date hereof, no Grantor holds any Commercial Tort Claims or has knowledge of any pending Commercial Tort Claims, except
for the Commercial Tort Claims described in Schedule VI.

 

    	 	13	 

     

    

 

(m)      All
of the Pledged Equity is presently owned by the applicable Grantor as set forth in Schedule XV, and is presently represented
by the certificates listed on Schedule XV hereto (if applicable). As of the date hereof, there are no existing options,
warrants, calls or commitments of any character whatsoever relating to the Pledged Equity other than as contemplated and permitted
by the Transaction Documents. Each Grantor is the sole holder of record and the sole beneficial owner of the Pledged Equity, as
applicable. None of the Pledged Equity has been issued or transferred in violation of the securities registration, securities
disclosure or similar laws of any jurisdiction to which such issuance or transfer may be subject. The Pledged Equity constitutes
100% or such other percentage as set forth on Schedule XV of the issued and outstanding shares of Capital Stock of the
applicable Pledged Entity.

 

(n)       Such
Grantor (i) is a corporation, limited liability company or limited partnership, as applicable, duly organized, validly existing
and in good standing under the laws of the jurisdiction of its incorporation, organization or formation, (ii) has all requisite
corporate, limited liability company or limited partnership power and authority to conduct its business as now conducted and as
presently contemplated and to execute and deliver this Agreement and each other Transaction Document to which such Grantor is
a party, and to consummate the transactions contemplated hereby and thereby and (iii) is duly qualified to do business and is
in good standing in each jurisdiction in which the character of the properties owned or leased by it or in which the transaction
of its business makes such qualification necessary, except where the failure to be so qualified would not result in a Material
Adverse Effect.

 

(o)       The
execution, delivery and performance by each Grantor of this Agreement and each other Transaction Document to which such Grantor
is a party (i) have been duly authorized by all necessary corporate, limited liability company or limited partnership action,
(ii) do not and will not contravene its charter or by-laws, limited liability company or operating agreement, certificate of partnership
or partnership agreement, as applicable, or any applicable law or any contractual restriction binding on such Grantor or its properties,
(iii) do not and will not result in or require the creation of any Lien (other than pursuant to any Transaction Document) upon
or with respect to any of its assets or properties, and (iv) do not and will not result in any default, noncompliance, suspension,
revocation, impairment, forfeiture or nonrenewal of any material permit, license, authorization or approval applicable to it or
its operations or any of its assets or properties.

 

(p)       This
Agreement and each of the other Transaction Documents to which any Grantor is or will be a party, when delivered, will be, a legal,
valid and binding obligation of such Grantor, enforceable against such Grantor in accordance with its terms, except as may be
limited by applicable bankruptcy, insolvency, reorganization, moratorium, fraudulent conveyance, suretyship or other similar laws
and equitable principles (regardless of whether enforcement is sought in equity or at law).

 

(q)       There
are no conditions precedent to the effectiveness of this Agreement that have not been satisfied or waived.

 

    	 	14	 

     

    

 

SECTION 5. Covenants
as to the Collateral. So long as any of the Obligations shall remain outstanding, unless the Collateral Agent shall otherwise
consent in writing:

 

(a)       Further
Assurances. Each Grantor will, at its expense, at any time and from time to time, promptly execute and deliver all further
instruments and documents and take all further action that the Collateral Agent may reasonably request in order to: (i) perfect
and protect the security interest of the Collateral Agent created hereby; (ii) enable the Collateral Agent to exercise and enforce
its rights and remedies hereunder in respect of the Collateral, including, without limitation, the Controlled Accounts; or (iii)
otherwise effect the purposes of this Agreement, including, without limitation: (A) marking conspicuously all Chattel Paper and
each License and, at the request of the Collateral Agent, each of its Records pertaining to the Collateral with a legend, in form
and substance satisfactory to the Collateral Agent, indicating that such Chattel Paper, License or Collateral is subject to the
security interest created hereby, (B) delivering and pledging to the Collateral Agent each Promissory Note, Security (subject
to the limitations set forth in Section 2), Chattel Paper or other Instrument, now or hereafter owned by any Grantor, duly
endorsed and accompanied by executed instruments of transfer or assignment, all in form and substance satisfactory to the Collateral
Agent, (C) executing and filing (to the extent, if any, that any Grantor’s signature is required thereon) or authenticating
the filing of, such financing or continuation statements, or amendments thereto, as may be necessary or that the Collateral Agent
may reasonably request in order to perfect and preserve the security interest created hereby, (D) furnishing to the Collateral
Agent from time to time statements and schedules further identifying and describing the Collateral and such other reports in connection
with the Collateral in each case as the Collateral Agent may reasonably request, all in reasonable detail, (E) if any Collateral
shall be in the possession of a third party, notifying such Person of the Collateral Agent’s security interest created hereby
and obtaining a written acknowledgment from such Person, in form and substance reasonably satisfactory to the Collateral Agent,
that such Person holds possession of the Collateral for the benefit of the Collateral Agent (for the benefit the Noteholders),
(F) if at any time after the date hereof, any Grantor acquires or holds any Commercial Tort Claim, promptly notifying the Collateral
Agent in a writing signed by such Grantor setting forth a brief description of such Commercial Tort Claim and granting to the
Collateral Agent a security interest therein and in the proceeds thereof, which writing shall incorporate the provisions hereof
and shall be in form and substance satisfactory to the Collateral Agent, (G) upon the acquisition after the date hereof by any
Grantor of any motor vehicle or other Equipment subject to a certificate of title or ownership (other than a motor vehicle or
Equipment that is subject to a purchase money security interest), causing the Collateral Agent to be listed as the lienholder
on such certificate of title or ownership and delivering evidence of the same to the Collateral Agent in accordance with Section
5(j) hereof; and (H) taking all actions required by the Code or by other law, as applicable, in any relevant Code jurisdiction,
or by other law as applicable in any foreign jurisdiction.

 

(b)       Location
of Collateral. Each Grantor will keep the Collateral (i) at the locations specified therefor on Schedule XVI hereto,
or (ii) at such other locations set forth on Schedule XVI and with respect to which the Collateral Agent has filed financing
statements and otherwise fully perfected its Liens thereon, or (iii) at such other locations in the United States , provided that
30 days prior to any change in the location of any Collateral to such other location, or upon the acquisition of any Collateral
to be kept at such other locations, the Grantors shall give the Collateral Agent written notice thereof and deliver to the Collateral
Agent a new Schedule XVI indicating such new locations and such other written statements and schedules as the Collateral
Agent may require.

 

(c)       Condition
of Equipment. Each Grantor will maintain or cause to be maintained and preserved in good condition, repair and working order,
ordinary wear and tear excepted, the Equipment (necessary or useful to its business) and will forthwith, or in the case of any
loss or damage to any Equipment of any Grantor within a commercially reasonable time after the occurrence thereof, make or cause
to be made all repairs, replacements and other improvements in connection therewith which are necessary or desirable, consistent
with past practice, or which the Collateral Agent may request to such end. Any Grantor will promptly furnish to the Collateral
Agent a statement describing in reasonable detail any such loss or damage in excess of $50,000 per occurrence to any Equipment.

 

    	 	15	 

     

    

 

(d)       Taxes,
Etc. Each Grantor agrees to pay promptly when due all property and other taxes, assessments and governmental charges or levies
imposed upon, and all claims (including claims for labor, materials and supplies) against, the Equipment and Inventory, except
to the extent the validity thereof is being contested in good faith by proper proceedings which stay the imposition of any penalty,
fine or Lien resulting from the non-payment thereof and with respect to which adequate reserves in accordance with GAAP have been
set aside for the payment thereof.

 

(e)       Insurance.

 

(i)       Each
Grantor will, at its own expense, maintain insurance (including, without limitation, comprehensive general liability, hazard,
rent and business interruption insurance) with respect to its properties (including all real properties leased or owned by it)
and business, in such amounts and covering such risks, in such form and with responsible and reputable insurance companies or
associations as is required by any Governmental Authority having jurisdiction with respect thereto or as is carried generally
in accordance with sound business practice by companies in similar businesses similarly situated and in any event, in amount,
adequacy and scope reasonably satisfactory to the Collateral Agent.

 

(ii)      To
the extent requested by the Collateral Agent at any time and from time to time, each such policy for liability insurance shall
provide for all losses to be paid on behalf of the Collateral Agent and any Grantor as their respective interests may appear,
and each policy for property damage insurance shall provide for all losses to be adjusted with, and paid directly to, the Collateral
Agent. In addition to and without limiting the foregoing, to the extent requested by the Collateral Agent at any time and from
time to time, each such policy shall in addition (A) name the Collateral Agent as an additional insured party and/or loss payee,
as applicable, thereunder (without any representation or warranty by or obligation upon the Collateral Agent) as its interests
may appear, (B) contain an agreement by the insurer that any loss thereunder shall be payable to the Collateral Agent on its own
account notwithstanding any action, inaction or breach of representation or warranty by any Grantor, (C) provide that there shall
be no recourse against the Collateral Agent for payment of premiums or other amounts with respect thereto, and (D) provide that
at least 30 days’ prior written notice of cancellation, lapse, expiration or other adverse change shall be given to the
Collateral Agent by the insurer. Any Grantor will, if so requested by the Collateral Agent, deliver to the Collateral Agent original
or duplicate policies of such insurance (including certificates demonstrating compliance with this Section 5(e)) and, as often
as the Collateral Agent may reasonably request, a report of a reputable insurance broker with respect to such insurance. Any Grantor
will also, at the request of the Collateral Agent, execute and deliver instruments of assignment of such insurance policies and
cause the respective insurers to acknowledge notice of such assignment.

 

    	 	16	 

     

    

 

(iii)      Reimbursement
under any liability insurance maintained by any Grantor pursuant to this Section 5(e) may be paid directly to the Person
who shall have incurred liability covered by such insurance. In the case of any loss involving damage to Equipment or Inventory,
to the extent paragraph (iv) of this Section 5(e) is not applicable, any proceeds of insurance involving such damage shall
be paid to the Collateral Agent, and any Grantor will make or cause to be made the necessary repairs to or replacements of such
Equipment or Inventory, and any proceeds of insurance maintained by any Grantor pursuant to this Section 5(e) (except as
otherwise provided in paragraph (iv) in this Section 5(e)) shall be paid by the Collateral Agent to any Grantor as reimbursement
for the reasonable costs of such repairs or replacements.

 

(iv)      Notwithstanding
anything to the contrary in subsection 5(e)(iii) above, following and during the continuance of an Event of Default (as defined
in the Securities Purchase Agreement and the ICA-T Note), all insurance payments in respect of each Grantor’s properties
and business shall be paid to the Collateral Agent and applied as specified in Section 7(b) hereof.

 

(f)       Provisions
Concerning the Accounts and the Licenses.

 

(i)        Each
Grantor will (A) give the Collateral Agent at least 30 days’ prior written notice of any change in such Grantor’s
name, identity or organizational structure, (B) maintain its jurisdiction of incorporation, organization or formation as set forth
in Schedule VII hereto, (C) immediately notify the Collateral Agent upon obtaining an organizational identification number,
if on the date hereof such Grantor did not have such identification number, and (D) keep adequate records concerning the Collateral
and permit representatives of the Collateral Agent during normal business hours on reasonable notice to such Grantor, to inspect
and make abstracts from such records.

 

    	 	17	 

     

    

 

(ii)      
Each Grantor will (except as otherwise provided in this subsection (f)), continue to collect, at its own expense, all amounts
due or to become due under the Accounts. In connection with such collections, any Grantor may (and, at the Collateral Agent’s
direction, will) take such action as any Grantor or the Collateral Agent may deem necessary or advisable to enforce collection
or performance of the Accounts that are not Excluded Collateral; provided, however, that the Collateral Agent shall
have the right at any time following the occurrence and during the continuance of an Event of Default to notify the Account Debtors
or obligors under any Accounts that are not Excluded Collateral of the assignment of such Accounts to the Collateral Agent and
to direct such Account Debtors or obligors to make payment of all amounts due or to become due to any Grantor thereunder directly
to the Collateral Agent or its designated agent and, upon such notification and at the expense of any Grantor and to the extent
permitted by applicable law, to enforce collection of any such Accounts and to adjust, settle or compromise the amount or payment
thereof, in the same manner and to the same extent as any Grantor might have done. After receipt by any Grantor of a notice from
the Collateral Agent that the Collateral Agent has notified, intends to notify, or has enforced or intends to enforce any Grantor’s
rights against the Account Debtors or obligors under any Accounts as referred to in the proviso to the immediately preceding sentence,
(A) all amounts and proceeds (including Instruments) received by any Grantor in respect of the Accounts shall be received in trust
for the benefit of the Collateral Agent hereunder (for the benefit the Noteholders), shall be segregated from other funds of any
Grantor and shall be forthwith paid over to the Collateral Agent in the same form as so received (with any necessary endorsement)
to be applied as specified in Section 7(b) hereof, and (B) no Grantor will adjust, settle or compromise the amount or payment
of any Account or release wholly or partly any Account Debtor or obligor thereof or allow any credit or discount thereon. In addition,
upon the occurrence and during the continuance of an Event of Default, the Collateral Agent may (in its sole and absolute discretion)
direct any or all of the banks and financial institutions with which any Grantor either maintains a Deposit Account or a lockbox
(including, without limitation, any Controlled Account) or deposits the proceeds of any Accounts to send immediately to the Collateral
Agent by wire transfer (to such deposit account as the Collateral Agent shall specify, or in such other manner as the Collateral
Agent shall direct) all or a portion of such securities, cash, investments and other items held by such institution. Any such
securities, cash, investments and other items so received by the Collateral Agent shall be applied as specified in accordance
with Section 7(b) hereof.

 

(iii)      
Upon the occurrence and during the continuance of any breach or default under any material License referred to in Schedule
XVII hereto by any party thereto other than any Grantor, each Grantor party thereto will, promptly after obtaining knowledge
thereof, give the Collateral Agent written notice of the nature and duration thereof, specifying what action, if any, it has taken
and proposes to take with respect thereto and thereafter will take reasonable steps to protect and preserve its rights and remedies
in respect of such breach or default, or will obtain or acquire an appropriate substitute License.

 

(iv)      
Each Grantor will, at its expense, promptly deliver to the Collateral Agent a copy of each notice or other communication received
by it by which any other party to any material License referred to in Schedule XVIII hereto purports to exercise any of
its rights or affect any of its obligations thereunder, together with a copy of any reply by such Grantor thereto.

 

(v)        Each
Grantor will exercise promptly and diligently each and every right which it may have under each material License (other than any
right of termination) and will duly perform and observe in all respects all of its obligations under each material License and
will take all action reasonably necessary to maintain such Licenses in full force and effect. No Grantor will, without the prior
written consent of the Collateral Agent, cancel, terminate, amend or otherwise modify in any respect, or waive any provision of,
any material License referred to in Schedule XIX hereto.

 

    	 	18	 

     

    

 

(g)       Transfers
and Other Liens.

 

(i)       Except
as otherwise expressly permitted in the other Transaction Documents, no Grantor shall, directly or indirectly, sell, lease, license,
assign, transfer, spin-off, split-off, close, convey or otherwise dispose of any Collateral whether in a single transaction or
a series of related transactions, other than (A) sales, leases, licenses, assignments, transfers, conveyances and other dispositions
of such assets or rights by such Grantor for value in the ordinary course of business consistent with past practices; and (B)
sales of Inventory and product in the ordinary course of business.

 

(ii)      Except
if expressly permitted under Section 14(e) of the ICA-T Note, no Grantor shall, directly or indirectly, redeem, repurchase or
declare or pay any cash dividend or distribution on any of its Capital Stock.

 

(iii)     No
Grantor shall, directly or indirectly, without the prior written consent of the Required Holders issue any securities that would
cause a breach or default under the ICA-T Note, the Securities Purchase Agreement and/or any other Transaction Document.

 

(iv)     Except
for payments to Taglich Brothers, Inc. or an Affiliate thereof for fundraising services they provide (but no payments shall be
made to any such parties related to any financing provided to any Grantor by the Buyer), no Grantor shall enter into, renew, extend
or be a party to, any transaction or series of related transactions (including, without limitation, the purchase, sale, lease,
transfer or exchange of property or assets of any kind or the rendering of services of any kind) with any Affiliate, except in
the ordinary course of business in a manner and to an extent consistent with past practice and necessary or desirable for the
prudent operation of its business, for fair consideration and on terms no less favorable to it than would be obtainable in a comparable
arm’s length transaction with a Person that is not an Affiliate thereof.

 

(v)       No
Grantor will create, suffer to exist or grant any Lien upon or with respect to any Collateral other than a Permitted Lien.

 

    	 	19	 

     

    

 

(h)       Intellectual
Property.

 

(i)       If
applicable, each Grantor shall duly execute and deliver the applicable Intellectual Property Security Agreement. Each Grantor
(either itself or through licensees) will, and will cause each licensee thereof to, take all action reasonably necessary and/or
requested by the Collateral Agent to maintain all of the Intellectual Property in full force and effect, including, without limitation,
using the proper statutory notices, numbers and markings (relating to patent, trademark and copyright rights) and using the Trademarks
on each applicable trademark class of goods in order to so maintain the Trademarks in full force and free from any claim of abandonment
for non-use, and each Grantor will not (nor permit any licensee thereof to) do any act or knowingly omit to do any act whereby
any Intellectual Property may become abandoned, cancelled or invalidated; provided, however, that so long as no
Event of Default has occurred and is continuing, no Grantor shall have an obligation to use or to maintain any Intellectual Property
(A) that relates solely to any product or work, that is no longer necessary or material and has been, or is in the process of
being, discontinued, abandoned or terminated in the ordinary course of business and consistent with the exercise of reasonable
business judgment, (B) that is being replaced with Intellectual Property substantially similar to the Intellectual Property that
may be abandoned or otherwise become invalid, so long as the failure to use or maintain such Intellectual Property does not materially
adversely affect the validity of such replacement Intellectual Property and so long as such replacement Intellectual Property
is subject to the Lien created by this Agreement and does not have a Material Adverse Effect on the business of any Grantor or
(C) that is substantially the same as another Intellectual Property that is in full force, so long the failure to use or maintain
such Intellectual Property does not materially adversely affect the validity of such replacement Intellectual Property and so
long as such other Intellectual Property is subject to the Lien and security interest created by this Agreement and does not have
a material adverse effect on the business of any Grantor. Each Grantor will cause to be taken all necessary steps in any proceeding
before the United States Patent and Trademark Office and the United States Copyright Office or any similar office or agency in
any other country or political subdivision thereof to maintain each registration of the Intellectual Property and application
for registration of Intellectual Property (other than the Intellectual Property described in the proviso to the immediately preceding
sentence), including, without limitation, filing of renewals, affidavits of use, affidavits of incontestability and opposition,
interference and cancellation proceedings and payment of maintenance fees, filing fees, taxes or other governmental fees. If any
Intellectual Property (other than Intellectual Property described in the proviso to the second sentence of subsection (i) of this
clause (h)) is infringed, misappropriated, diluted or otherwise violated in any material respect by a third party, each Grantor
shall (x) upon learning of such infringement, misappropriation, dilution or other violation, promptly (but in no event more than
five (5) business days after learning of such) notify the Collateral Agent and (y) if reasonably requested by the Collateral Agent
promptly sue for infringement, misappropriation, dilution or other violation, seek injunctive relief where appropriate and recover
any and all damages for such infringement, misappropriation, dilution or other violation, or take such other actions as such Grantor
shall deem appropriate under the circumstances to protect such Intellectual Property. Each Grantor shall furnish to the Collateral
Agent from time to time upon its request statements and schedules further identifying and describing the Intellectual Property
and Licenses and such other reports in connection with the Intellectual Property and Licenses as the Collateral Agent may reasonably
request, all in reasonable detail and promptly upon request of the Collateral Agent, following receipt by the Collateral Agent
of any such statements, schedules or reports, each Grantor shall modify this Agreement by amending Schedules II, III and IV
and any other applicable Schedule hereto, as the case may be, to include any Intellectual Property and License, as the case
may be, which is or hereafter becomes part of the Collateral under this Agreement and shall execute and authenticate such documents
and do such acts as shall be necessary or, in the reasonable judgment of the Collateral Agent, desirable to subject such Intellectual
Property and Licenses to the Lien and security interest created by this Agreement. Notwithstanding anything herein to the contrary,
upon the occurrence and during the continuance of an Event of Default, no Grantor may abandon, surrender or otherwise permit any
Intellectual Property to become abandoned, cancelled or invalid without the prior written consent of the Collateral Agent, and
if any Intellectual Property is infringed, misappropriated, diluted or otherwise violated in any material respect by a third party,
each Grantor will take such reasonable action as the Collateral Agent shall deem appropriate under the circumstances to protect
such Intellectual Property.

 

    	 	20	 

     

    

 

(ii)       In
the event that any Grantor, either itself or through any agent, employee, licensee or designee, files an application for the registration
of any Patent, Trademark or Copyright or the United States Copyright Office or the United States Patent and Trademark Office,
as applicable, or in any similar office or agency of the United States or any country or any political subdivision thereof, it
shall give the Collateral Agent prompt written notice thereof (but in no event more than one (1) business day after the initial
filing of application). Upon request of the Collateral Agent, any Grantor shall execute, authenticate and deliver any and all
assignments, agreements, instruments, documents and papers as the Collateral Agent may reasonably request to evidence the Collateral
Agent’s security interest hereunder in such Intellectual Property and the General Intangibles of any Grantor relating thereto
or represented thereby, and each Grantor hereby appoints the Collateral Agent its attorney-in-fact to execute and/or authenticate
and file all such writings for the foregoing purposes, all acts of such attorney being hereby ratified and confirmed, and such
power (being coupled with an interest) shall be irrevocable until all Obligations are Paid in Full.

 

(i)       Pledged
Accounts.

 

(A)       Each
Grantor shall use its reasonable best efforts to, as soon as practical following the Closing Date, but in no event more than sixty
(60) calendar days following the Closing Date (the “CAB Period”), cause each bank and other financial institution
which maintains a Controlled Account (each a “Controlled Account Bank”) to execute and deliver to the Collateral
Agent, in form and substance satisfactory to the Collateral Agent, a Controlled Account Agreement with respect to such Controlled
Account, duly executed by each Grantor and such Controlled Account Bank, pursuant to which such Controlled Account Bank among
other things shall irrevocably agree, with respect to such Controlled Account, that (i) at any time after any Grantor, the Collateral
Agent or the Buyer shall have notified such Controlled Account Bank that an Event of Default has occurred or is continuing, such
Controlled Account Bank will comply with any and all instructions originated by the Collateral Agent directing the disposition
of the funds in such Controlled Account without further consent by such Grantor, (ii) such Controlled Account Bank shall waive,
subordinate or agree not to exercise any rights of setoff or recoupment or any other claim against the applicable Controlled Account
other than for payment of its service fees and other charges directly related to the administration of such Controlled Account
and for returned checks or other items of payment, (iii) at any time after any Grantor, the Collateral Agent or the Buyer shall
have notified such Controlled Account Bank that an Event of Default has occurred or is continuing, with respect to each such Controlled
Account, such Controlled Account Bank shall not comply with any instructions, directions or orders of any form with respect to
such Controlled Accounts other than instructions, directions or orders originated by the Collateral Agent, (iv) all funds deposited
by any Grantor with such Controlled Account Bank shall be subject to a perfected, first priority security interest in favor of
the Collateral Agent, and (v) upon receipt of written notice from the Collateral Agent during the continuance of an Event of Default,
such Controlled Account Bank shall immediately send to the Collateral Agent by wire transfer (to such account as the Collateral
Agent shall specify, or in such other manner as the Collateral Agent shall direct) all such funds and other items held by it.
No Grantor shall create or maintain any Pledged Account without the prior written consent of the Collateral Agent and complying
with the terms of this Agreement.

 

    	 	21	 

     

    

 

(B)       If
at any time after the expiration of the CAB Period, the average daily balance of any Account that is not subject to a Controlled
Account Agreement exceeds $100,000 during any calendar month (including the calendar month in which the Closing Date occurs),
the Parent shall, either (x) within two (2) Business Days following such date, transfer to a Controlled Account an amount sufficient
to reduce the total aggregate amount of the cash in such Account to an amount not in excess of $100,000 or (y) within twenty-one
(21) calendar days following the last day of such calendar month, deliver to the Collateral Agent a Controlled Account Agreement
with respect to such Account, duly executed by such Grantor and the depositary bank in which such Account is maintained.

 

(C)       Notwithstanding
anything to the contrary contained in Section 5(i)(B) above, and without limiting any of the foregoing, if at any time
after the expiration of the CAB Period, the total aggregate amount of the cash of the Parent and any of its Subsidiaries, in the
aggregate, that is not held in a Controlled Account exceeds $150,000 (the “Maximum Free Cash Amount”), the
Parent shall within twenty one (21) Business Days following such date, either (x) transfer to a Controlled Account an amount sufficient
to reduce the total aggregate amount of the cash that is not held in a Controlled Account to an amount not in excess of the Maximum
Free Cash Amount or (y) deliver to the Collateral Agent a Controlled Account Agreement with respect to such Account (or Accounts),
duly executed by such Grantor and the depositary bank in which such Account (or Accounts) is maintained, as necessary to reduce
the total aggregate amount of the cash that is not held in a Controlled Account to an amount not in excess of the Maximum Free
Cash Amount.

 

(j)       Control.
Each Grantor hereby agrees to take any or all action that may be necessary or that the Collateral Agent may reasonably request
in order for the Collateral Agent to obtain “control” in accordance with Sections 9-105 through 9-107 of the Code
with respect to the following Collateral: (i) Electronic Chattel Paper, (ii) Investment Property, and (iii) Letter-of-Credit Rights.

 

    	 	22	 

     

    

 

(k)       Inspection
and Reporting. Each Grantor shall permit the Collateral Agent, or any agent or representatives thereof or such professionals
or other Persons as the Collateral Agent may designate at Grantors’ sole cost and expense no more than once per quarter
(the “Quarterly Limitations”), unless an Event of Default exists and/or with the passage of time, the occurrence
of an event or the giving of notice an Event of Default would exist, in which event there shall be no limitations including, but
not limited to, the Quarterly Limitations (i) to examine and make copies of and abstracts from any Grantor’s records and
books of account, (ii) to visit and inspect its properties, (iii) to verify materials, leases, Instruments, Accounts, Inventory
and other assets of any Grantor from time to time, and (iv) to conduct audits, physical counts, appraisals and/or valuations,
examinations at the locations of any Grantor. Each Grantor shall also permit the Collateral Agent, or any agent or representatives
thereof or such attorneys, accountants or other professionals or other Persons as the Collateral Agent may designate to discuss
such Grantor’s affairs, finances and accounts with any of its directors, officers, members, managers managerial employees,
independent accountants or any of its other representatives. Without limiting the foregoing, the Collateral Agent may, at any
time, in the Collateral Agent’s own name, in the name of a nominee of the Collateral Agent, or in the name of any Grantor
communicate (by mail, telephone, facsimile or otherwise) with the Account Debtors of such Grantor, parties to contracts with such
Grantor and/or obligors in respect of Instruments of such Grantor to verify with such Persons, to the Collateral Agent’s
satisfaction, the existence, amount, terms of, and any other matter relating to, Accounts, Instruments, Chattel Paper, payment
intangibles and/or other receivables.

 

(l)       Future
Subsidiaries. If any Grantor hereafter creates or acquires any Subsidiary, simultaneously with the creation or acquisition
of such Subsidiary, such Grantor shall (i) if such Subsidiary is a Domestic Subsidiary, cause such Subsidiary to become a party
to this Agreement as an additional “Grantor” hereunder, (ii) deliver to the Collateral Agent updated Schedules to
this Agreement, as appropriate (including, without limitation, an updated Schedule IV to reflect the grant by such Grantor
of a Lien on all Pledged Equity now or hereafter owned by such Grantor), (iii) if such Subsidiary is a Domestic Subsidiary, cause
such Subsidiary to duly execute and deliver a guaranty of the Obligations in favor of the Collateral Agent in form and substance
acceptable to the Collateral Agent, (iv) if such Subsidiary is a (a) Domestic Subsidiary, deliver to the Collateral Agent the
stock certificates representing all, and (b) so long as permitted by applicable law, Foreign Subsidiary, deliver to the Collateral
Agent the stock certificates representing 65%, of the Capital Stock of such Subsidiary, along with undated stock powers for each
such certificates, executed in blank (or, if any such shares of Capital Stock are uncertificated, confirmation and evidence reasonably
satisfactory to the Collateral Agent that the security interest in such uncertificated securities has been transferred to and
perfected by the Collateral Agent, in accordance with Sections 8-313, 8-321 and 9-115 of the Code or any other similar or local
or foreign law that may be applicable), and (v) duly execute and/or cause to be delivered to the Collateral Agent, in form and
substance acceptable to the Collateral Agent, such opinions of counsel and other documents as the Collateral Agent shall request
with respect thereto; provided, however, that no Grantor shall be required to pledge any Excluded Collateral. Each
Grantor hereby authorizes the Collateral Agent to attach such updated Schedules to this Agreement and agrees that all Pledged
Equity listed on any updated Schedule delivered to the Collateral Agent shall for all purposes hereunder be considered Collateral.
The Grantors agree that the pledge of the shares of Capital Stock acquired by a Grantor of Foreign Subsidiary may be supplemented
by one or more separate pledge agreements, deeds of pledge, share charges, or other similar agreements or instruments, executed
and delivered by the relevant Grantor in favor of the Collateral Agent, which pledge agreements will provide for the pledge of
such shares of Capital Stock in accordance with the laws of the applicable foreign jurisdiction. With respect to such shares of
Capital Stock, the Collateral Agent may, at any time and from time to time, in its sole discretion, take actions in such foreign
jurisdictions that will result in the perfection of the Lien created in such shares of Capital Stock other than Excluded Collateral.

 

    	 	23	 

     

    

 

SECTION 6. Additional
Provisions Concerning the Collateral.

 

(a)       To
the maximum extent permitted by applicable law, and for the purpose of taking any action that the Collateral Agent may deem necessary
or advisable to accomplish the purposes of this Agreement, each Grantor hereby (i) authorizes the Collateral Agent to execute
any such agreements, instruments or other documents in such Grantor’s name and to file such agreements, instruments or other
documents in such Grantor’s name and in any appropriate filing office, (ii) authorizes the Collateral Agent at any time
and from time to time to file, one or more financing or continuation statements, and amendments thereto, relating to the Collateral
(including, without limitation, any such financing statements that (A) describe the Collateral as “all assets” or
“all personal property” (or words of similar effect) other than Excluded Collateral or that describe or identify the
Collateral by type or in any other manner as the Collateral Agent may determine regardless of whether any particular asset of
such Grantor falls within the scope of Article 9 of the Code or whether any particular asset of such Grantor constitutes part
of the Collateral, and (B) contain any other information required by Part 5 of Article 9 of the Code for the sufficiency or filing
office acceptance of any financing statement, continuation statement or amendment, including, without limitation, whether such
Grantor is an organization, the type of organization and any organizational identification number issued to such Grantor) and
(iii) ratifies such authorization to the extent that the Collateral Agent has filed any such financing or continuation statements,
or amendments thereto, prior to the date hereof. A photocopy or other reproduction of this Agreement or any financing statement
covering the Collateral or any part thereof shall be sufficient as a financing statement where permitted by law.

 

(b)       Each
Grantor hereby irrevocably appoints (but Collateral Agent shall not use such power until an Event of Default occurs) the Collateral
Agent as its attorney-in-fact and proxy, with full authority in the place and stead of such Grantor and in the name of such Grantor
or otherwise, from time to time in the Collateral Agent’s discretion to take any action and to execute any instrument which
the Collateral Agent may deem necessary or advisable to accomplish the purposes of this Agreement, including, without limitation,
(i) to obtain and adjust insurance required to be paid to the Collateral Agent pursuant to Section 5(e) hereof, (ii) to
ask, demand, collect, sue for, recover, compound, receive and give acquittance and receipts for moneys due and to become due under
or in respect of any Collateral, (iii) to receive, endorse, and collect any drafts or other instruments, documents and chattel
paper in connection with clause (i) or (ii) above, (iv) to file any claims or take any action or institute any proceedings which
the Collateral Agent may deem necessary or desirable for the collection of any Collateral or otherwise to enforce the rights of
the Collateral Agent and the Noteholders with respect to any Collateral, (v) to execute assignments, licenses and other documents
to enforce the rights of the Collateral Agent and the Noteholders with respect to any Collateral, and (vi) to verify any and all
information with respect to any and all Accounts. This power is coupled with an interest and is irrevocable until all of the Obligations
are Paid in Full.

 

    	 	24	 

     

    

 

(c)       For
the purpose of enabling the Collateral Agent to exercise rights and remedies hereunder, at such time as the Collateral Agent shall
be lawfully entitled to exercise such rights and remedies, and for no other purpose, each Grantor hereby grants to the Collateral
Agent, to the extent assignable, an irrevocable, non-exclusive license (exercisable without payment of royalty or other compensation
to any Grantor) to use, assign, license or sublicense any Intellectual Property now owned or hereafter acquired by such Grantor,
wherever the same may be located, including in such license reasonable access to all media in which any of the licensed items
may be recorded or stored and to all computer programs used for the compilation or printout thereof. Notwithstanding anything
contained herein to the contrary, but subject to the provisions of the Securities Purchase Agreement that limit the right of any
Grantor to dispose of its property, and Section 5(g) and Section 5(h) hereof, so long as no Event of Default shall
have occurred and be continuing, any Grantor may exploit, use, enjoy, protect, license, sublicense, assign, sell, dispose of or
take other actions with respect to the Intellectual Property in the ordinary course of its business and as otherwise expressly
permitted by any of the other Transaction Documents. In furtherance of the foregoing, unless an Event of Default shall have occurred
and be continuing, the Collateral Agent shall from time to time, upon the request of any Grantor, execute and deliver any instruments,
certificates or other documents, in the form so requested, which such Grantor shall have certified are appropriate (in such Grantor’s
judgment) to allow it to take any action permitted above (including relinquishment of the license provided pursuant to this clause
(c) as to any Intellectual Property). Further, upon the Payment in Full of all of the Obligations, the Collateral Agent (subject
to Section 10(e) hereof) shall release and reassign to any Grantor all of the Collateral Agent’s right, title and
interest in and to the Collateral, including the Intellectual Property, and the Licenses, all without recourse, representation
or warranty whatsoever. The exercise of rights and remedies hereunder by the Collateral Agent shall not terminate the rights of
the holders of any licenses or sublicenses theretofore granted by each Grantor in accordance with the second sentence of this
clause (c). Each Grantor hereby releases the Collateral Agent from any claims, causes of action and demands at any time arising
out of or with respect to any actions taken or omitted to be taken by the Collateral Agent under the powers of attorney granted
herein other than actions taken or omitted to be taken through the Collateral Agent’s gross negligence or willful misconduct,
as determined by a final determination of a court of competent jurisdiction.

 

(d)       If
any Grantor fails to perform any agreement or obligation contained herein, upon an Event of Default, the Collateral Agent may
itself perform, or cause performance of, such agreement or obligation, in the name of such Grantor or the Collateral Agent, and
the expenses of the Collateral Agent incurred in connection therewith shall be payable by such Grantor pursuant to Section
8 hereof and shall be secured by the Collateral.

 

    	 	25	 

     

    

 

(e)       The
powers conferred on the Collateral Agent hereunder are solely to protect its interest in the Collateral and shall not impose any
duty upon it to exercise any such powers. Except for the safe custody of any Collateral in its possession and the accounting for
moneys actually received by it hereunder, the Collateral Agent shall have no duty as to any Collateral or as to the taking of
any necessary steps to preserve rights against prior parties or any other rights pertaining to any Collateral.

 

(f)       Anything
herein to the contrary notwithstanding (i) each Grantor shall remain liable under the Licenses and otherwise with respect to any
of the Collateral to the extent set forth therein to perform all of its obligations thereunder to the same extent as if this Agreement
had not been executed, (ii) the exercise by the Collateral Agent of any of its rights hereunder shall not release any Grantor
from any of its obligations under the Licenses or otherwise in respect of the Collateral, and (iii) the Collateral Agent shall
not have any obligation or liability by reason of this Agreement under the Licenses or with respect to any of the other Collateral,
nor shall the Collateral Agent be obligated to perform any of the obligations or duties of any Grantor thereunder or to take any
action to collect or enforce any claim for payment assigned hereunder.

 

(g)       As
long as no Event of Default (as defined under the Notes) shall have occurred and be continuing and until written notice shall
be given to the applicable Grantor:

 

(i)       Each
Grantor shall have the right, from time to time, to vote and give consents with respect to the Pledged Equity, or any part thereof
for all purposes not inconsistent with the provisions of this Agreement, the Securities Purchase Agreement or any other Transaction
Document; provided, however, that no vote shall be cast, and no consent shall be given or action taken, which would
have the effect of impairing the position or interest of the Collateral Agent in respect of the Pledged Equity or which would
authorize, effect or consent to (unless and to the extent expressly permitted by the Securities Purchase Agreement):

 

(A)       the
dissolution or liquidation, in whole or in part, of a Pledged Entity;

 

(B)       the
consolidation or merger of a Pledged Entity with any other Person;

 

(C)       the
sale, disposition or encumbrance of all or substantially all of the assets of a Pledged Entity, except for Liens in favor of the
Collateral Agent;

 

(D)       any
change in the authorized number of shares, the stated capital or the authorized share capital of a Pledged Entity or the issuance
of any additional shares of its Capital Stock; or

 

(E)       the
alteration of the voting rights with respect to the Capital Stock of a Pledged Entity.

 

    	 	26	 

     

    

 

(ii)       Each
Grantor shall be entitled, from time to time, to collect and receive for its own use all cash dividends and interest paid in respect
of the Pledged Equity to the extent not in violation of the Securities Purchase Agreement other than any and all: (A) dividends
and interest paid or payable other than in cash in respect of any Pledged Equity, and instruments and other property received,
receivable or otherwise distributed in respect of, or in exchange for, any Pledged Equity; (B) dividends and other distributions
paid or payable in cash in respect of any Pledged Equity in connection with a partial or total liquidation or dissolution or in
connection with a reduction of capital, capital surplus or paid-in capital of a Pledged Entity; and (C) cash paid, payable or
otherwise distributed, in respect of principal of, or in redemption of, or in exchange for, any Pledged Equity; provided,
however, that until actually paid all rights to such distributions shall remain subject to the Lien created by this Agreement;
and

 

(iii)       all
dividends and interest (other than such cash dividends and interest as are permitted to be paid to any Grantor in accordance with
clause (i) above) and all other distributions in respect of any of the Pledged Equity, whenever paid or made, shall be delivered
to the Collateral Agent to hold as Pledged Equity and shall, if received by any Grantor, be received in trust for the benefit
of the Collateral Agent (for the benefit of the Noteholders), be segregated from the other property or funds of such Grantor,
and be forthwith delivered to the Collateral Agent as Pledged Equity in the same form as so received (with any necessary endorsement).

 

SECTION 7. Remedies
Upon Event of Default; Application of Proceeds. If any Event of Default shall have occurred and be continuing:

 

(a)       The
Collateral Agent may exercise in respect of the Collateral, in addition to any other rights and remedies provided for herein,
in any other Transaction Document or otherwise available to it, all of the rights and remedies of a secured party upon default
under the Code (whether or not the Code applies to the affected Collateral), and also may (i) take absolute control of the Collateral,
including, without limitation, transfer into the Collateral Agent’s name or into the name of its nominee or nominees (to
the extent the Collateral Agent has not theretofore done so) and thereafter receive, for the benefit of the Noteholders, all payments
made thereon, give all consents, waivers and ratifications in respect thereof and otherwise act with respect thereto as though
it were the outright owner thereof, (ii) require each Grantor to, and each Grantor hereby agrees that it will at its expense and
upon request of the Collateral Agent forthwith, assemble all or part of its respective Collateral as directed by the Collateral
Agent and make it available to the Collateral Agent at a place or places to be designated by the Collateral Agent that is reasonably
convenient to both parties, and the Collateral Agent may enter into and occupy any premises owned or leased by any Grantor where
the Collateral or any part thereof is located or assembled for a reasonable period in order to effectuate the Collateral Agent’s
rights and remedies hereunder or under law, without obligation to any Grantor in respect of such occupation, and (iii) without
notice except as specified below and without any obligation to prepare or process the Collateral for sale, (A) sell the Collateral
or any part thereof in one or more parcels at public or private sale (including, without limitation, by credit bid), at any of
the Collateral Agent’s offices or elsewhere, for cash, on credit or for future delivery, and at such price or prices and
upon such other terms as the Collateral Agent may deem commercially reasonable and/or (B) lease, license or dispose of the Collateral
or any part thereof upon such terms as the Collateral Agent may deem commercially reasonable. Each Grantor agrees that, to the
extent notice of sale or any other disposition of its respective Collateral shall be required by law, at least ten (10) days’
notice to any Grantor of the time and place of any public sale or the time after which any private sale or other disposition of
its respective Collateral is to be made shall constitute reasonable notification. The Collateral Agent shall not be obligated
to make any sale or other disposition of any Collateral regardless of notice of sale having been given. The Collateral Agent may
adjourn any public or private sale from time to time by announcement at the time and place fixed therefor, and such sale may,
without further notice, be made at the time and place to which it was so adjourned. Each Grantor hereby waives any claims against
the Collateral Agent and the Noteholders arising by reason of the fact that the price at which its respective Collateral may have
been sold at a private sale was less than the price which might have been obtained at a public sale or was less than the aggregate
amount of the Obligations, even if the Collateral Agent accepts the first offer received and does not offer such Collateral to
more than one offeree, and waives all rights that any Grantor may have to require that all or any part of such Collateral be marshaled
upon any sale (public or private) thereof. Each Grantor hereby acknowledges that (i) any such sale of its respective Collateral
by the Collateral Agent shall be made without warranty, (ii) the Collateral Agent may specifically disclaim any warranties of
title, possession, quiet enjoyment or the like, and (iii) such actions set forth in clauses (i) and (ii) above shall not adversely
affect the commercial reasonableness of any such sale of Collateral. In addition to the foregoing, (1) upon written notice to
any Grantor from the Collateral Agent after and during the continuance of an Event of Default, such Grantor shall cease any use
of the Intellectual Property or any trademark, patent or copyright similar thereto for any purpose described in such notice; (2)
the Collateral Agent may, at any time and from time to time after and during the continuance of an Event of Default, upon 5 days’
prior notice to such Grantor, license, whether general, special or otherwise, and whether on an exclusive or non-exclusive basis,
any of the Intellectual Property, throughout the universe for such term or terms, on such conditions, and in such manner, as the
Collateral Agent shall in its sole discretion determine; and (3) the Collateral Agent may, at any time, pursuant to the authority
granted in Section 6 hereof or otherwise (such authority being effective upon the occurrence and during the continuance
of an Event of Default), execute and deliver on behalf of such Grantor, one or more instruments of assignment of the Intellectual
Property (or any application or registration thereof), in form suitable for filing, recording or registration in any country.

 

    	 	27	 

     

    

 

(b)       Any
cash held by the Collateral Agent as Collateral and all Cash Proceeds received by the Collateral Agent in respect of any sale
or disposition of or collection from, or other realization upon, all or any part of the Collateral shall be applied as follows
(subject to the provisions of the Securities Purchase Agreement): first, to pay any fees, indemnities or expense reimbursements
then due to the Collateral Agent (including those described in Section 8 hereof); second, to pay any fees, indemnities
or expense reimbursements then due to the Noteholders, on a pro rata basis; third to pay interest due under the ICA-T Note
owing to the Noteholders, on a pro rata basis; fourth, to pay or prepay principal in respect of the ICA-T Note, whether
or not then due, owing to the Noteholders, on a pro rata basis; fifth, to pay or prepay any other Obligations, whether
or not then due, in such order and manner as the Collateral Agent shall elect, consistent with the provisions of the Securities
Purchase Agreement and any other Transaction Document. Any surplus of such cash or Cash Proceeds held by the Collateral Agent
and remaining after the Payment in Full of all of the Obligations shall be paid over to whomsoever shall be lawfully entitled
to receive the same or as a court of competent jurisdiction shall direct.

 

(c)       In
the event that the proceeds of any such sale, disposition, collection or realization are insufficient to pay all amounts to which
the Collateral Agent and the Noteholders are legally entitled, each Grantor shall be, jointly and severally, liable for the deficiency,
together with interest thereon at the highest rate specified in the ICA-T Note for interest on overdue principal thereof or such
other rate as shall be fixed by applicable law, together with the costs of collection and the fees, costs, expenses and other
charges of any attorneys employed by the Collateral Agent to collect such deficiency.

 

(d)       To
the extent that applicable law imposes duties on the Collateral Agent to exercise remedies in a commercially reasonable manner,
each Grantor acknowledges and agrees that it is commercially reasonable for the Collateral Agent (i) to fail to incur expenses
deemed significant by the Collateral Agent to prepare Collateral for disposition or otherwise to transform raw material or work
in process into finished goods or other finished products for disposition, (ii) to fail to obtain third party consents for access
to Collateral to be disposed of, or to obtain or, if not required by other law, to fail to obtain governmental or third party
consents for the collection or disposition of Collateral to be collected or disposed of, (iii) to fail to exercise collection
remedies against Account Debtors or other Persons obligated on Collateral or to remove Liens on or any adverse claims against
Collateral, (iv) to exercise collection remedies against Account Debtors and other Persons obligated on Collateral directly or
through the use of collection agencies and other collection specialists, (v) to advertise dispositions of Collateral through publications
or media of general circulation, whether or not the Collateral is of a specialized nature, (vi) to contact other Persons, whether
or not in the same business as any Grantor, for expressions of interest in acquiring all or any portion of such Collateral, (vii)
to hire one or more professional auctioneers to assist in the disposition of Collateral, whether or not the Collateral is of a
specialized nature, (viii) to dispose of Collateral by utilizing internet sites that provide for the auction of assets of the
types included in the Collateral or that have the reasonable capacity of doing so, or that match buyers and sellers of assets,
(ix) to dispose of assets in wholesale rather than retail markets, (x) to disclaim disposition warranties, such as title, possession
or quiet enjoyment, (xi) to purchase insurance or credit enhancements to insure the Collateral Agent against risks of loss, collection
or disposition of Collateral or to provide to the Collateral Agent a guaranteed return from the collection or disposition of Collateral,
or (xii) to the extent deemed appropriate by the Collateral Agent, to obtain the services of brokers, investment bankers, consultants,
attorneys and other professionals to assist the Collateral Agent in the collection or disposition of any of the Collateral. Each
Grantor acknowledges that the purpose of this section is to provide non-exhaustive indications of what actions or omissions by
the Collateral Agent would be commercially reasonable in the Collateral Agent’s exercise of remedies against the Collateral
and that other actions or omissions by the Collateral Agent shall not be deemed commercially unreasonable solely on account of
not being indicated in this section. Without limitation upon the foregoing, nothing contained in this section shall be construed
to grant any rights to any Grantor or to impose any duties on the Collateral Agent that would not have been granted or imposed
by this Agreement or by applicable law in the absence of this section.

 

    	 	28	 

     

    

 

(e)       The
Collateral Agent shall not be required to marshal any present or future collateral security (including, but not limited to, this
Agreement and the Collateral) for, or other assurances of payment of, the Obligations or any of them or to resort to such collateral
security or other assurances of payment in any particular order, and all of the Collateral Agent’s rights hereunder and
in respect of such collateral security and other assurances of payment shall be cumulative and in addition to all other rights,
however existing or arising. To the extent that any Grantor lawfully may, each Grantor hereby agrees that it will not invoke any
law relating to the marshaling of collateral which might cause delay in or impede the enforcement of the Collateral Agent’s
rights under this Agreement or under any other instrument creating or evidencing any of the Obligations or under which any of
the Obligations is outstanding or by which any of the Obligations is secured or payment thereof is otherwise assured, and, to
the extent that it lawfully may, each Grantor hereby irrevocably waives the benefits of all such laws.

 

SECTION 8. Indemnity
and Expenses.

 

(a)       Each
Grantor agrees, jointly and severally, to defend, protect, indemnify and hold the Collateral Agent and each of the Noteholders
harmless from and against any and all claims, damages, losses, liabilities, obligations, penalties, fees, costs and expenses (including,
without limitation, legal fees, costs, expenses, and disbursements of such Person’s counsel) to the extent that they arise
out of or otherwise result from this Agreement (including, without limitation, enforcement of this Agreement), except to the extent
resulting from such Person’s gross negligence or willful misconduct, as determined by a final judgment of a court of competent
jurisdiction no longer subject to appeal.

 

(b)       Each
Grantor agrees, jointly and severally, to pay to the Collateral Agent upon demand the amount of any and all costs and expenses,
including the reasonable fees, costs, expenses and disbursements of counsel for the Collateral Agent and of any experts and agents
(including, without limitation, any collateral trustee which may act as agent of the Collateral Agent), which the Collateral Agent
may incur in connection with (i) the preparation, negotiation, execution, delivery, recordation, administration, amendment, waiver
or other modification or termination of this Agreement, (ii) the custody, preservation, use or operation of, or the sale of, collection
from, or other realization upon, any Collateral, (iii) the exercise or enforcement of any of the rights of the Collateral Agent
hereunder, or (iv) the failure by any Grantor to perform or observe any of the provisions hereof.

 

SECTION 9. Notices,
Etc. All notices and other communications provided for hereunder shall be in writing and shall be mailed (by certified mail,
first-class postage prepaid and return receipt requested), telecopied, e-mailed or delivered, if to any Grantor (other than ICA-T),
to the Parent’s address, if to ICA-T, to ICA-T’s address or if to the Collateral Agent or any Noteholder, to it at
its respective address, each as set forth in Section 9(f) of the Securities Purchase Agreement; or as to any such Person, at such
other address as shall be designated by such Person in a written notice to all other parties hereto complying as to delivery with
the terms of this Section 9. All such notices and other communications shall be effective (a) if sent by certified mail,
return receipt requested, when received or three (3) Business Days after deposited in the mails, whichever occurs first, (b) if
telecopied or e-mailed, when transmitted (during normal business hours) and confirmation is received, and otherwise, the day after
the notice or communication was transmitted and confirmation is received, or (c) if delivered in person, upon delivery. For the
avoidance of doubt, all Foreign Subsidiaries, as Grantors, hereby appoint the Parent as its agent for receipt of service of process
and all notices and other communications in the United States at the address specified below.

 

    	 	29	 

     

    

 

SECTION 10. Miscellaneous.

 

(a)       No
amendment of any provision of this Agreement shall be effective unless it is in writing and signed by each Grantor and the Collateral
Agent (and approved by the Required Holders), and no waiver of any provision of this Agreement, and no consent to any departure
by each Grantor therefrom, shall be effective unless it is in writing and signed by each Grantor and the Collateral Agent (and
approved by the Required Holders), and then such waiver or consent shall be effective only in the specific instance and for the
specific purpose for which given.

 

(b)       No
failure on the part of the Collateral Agent to exercise, and no delay in exercising, any right reasonably hereunder or under any
of the other Transaction Documents shall operate as a waiver thereof; nor shall any single or partial exercise of any such right
reasonably preclude any other or further exercise thereof or the exercise of any other right. The rights and remedies of the Collateral
Agent or any Noteholder provided herein and in the other Transaction Documents are cumulative and are in addition to, and not
exclusive of, any rights or remedies provided by law. The rights of the Collateral Agent or any Noteholder under any of the other
Transaction Documents against any party thereto are not conditional or contingent on any attempt by such Person to exercise any
of its rights under any of the other Transaction Documents against such party or against any other Person, including but not limited
to, any Grantor.

 

(c)       If
any provision of this Agreement or any Transaction Document is prohibited by law or otherwise determined to be invalid or unenforceable
by a court of competent jurisdiction, the provision that would otherwise be prohibited, invalid or unenforceable shall be deemed
amended to apply to the broadest extent that it would be valid and enforceable, and the invalidity or unenforceability of such
provision shall not affect the validity of the remaining provisions of this Agreement so long as this Agreement as so modified
continues to express, without material change, the original intentions of the parties as to the subject matter hereof and the
prohibited nature, invalidity or unenforceability of the provision(s) in question does not substantially impair the respective
expectations or reciprocal obligations of the parties or the practical realization of the benefits that would otherwise be conferred
upon the parties.  The parties will endeavor in good faith negotiations to replace the prohibited, invalid or unenforceable
provision(s) with a valid provision(s), the effect of which comes as close as possible to that of the prohibited, invalid or unenforceable
provision(s).

 

(d)       This
Agreement shall create a continuing security interest in the Collateral and shall (i) remain in full force and effect until Payment
in Full of the Obligations, and (ii) be binding on each Grantor and all other Persons who become bound as debtor to this Agreement
in accordance with Section 9-203(d) of the Code and shall inure, together with all rights and remedies of the Collateral Agent
and the Noteholders hereunder, to the benefit of the Collateral Agent and the Noteholders and their respective permitted successors,
transferees and assigns. Without limiting the generality of clause (ii) of the immediately preceding sentence, without notice
to any Grantor, the Collateral Agent and the Noteholders may assign or otherwise transfer their rights and obligations under this
Agreement and any of the other Transaction Documents, to any other Person and such other Person shall thereupon become vested
with all of the benefits in respect thereof granted to the Collateral Agent and the Noteholders herein or otherwise. Upon any
such assignment or transfer, all references in this Agreement to the Collateral Agent or any such Noteholder shall mean the assignee
of the Collateral Agent or such Noteholder. None of the rights or obligations of any Grantor hereunder may be assigned or otherwise
transferred without the prior written consent of the Collateral Agent, and any such assignment or transfer without such consent
of the Collateral Agent shall be null and void.

 

    	 	30	 

     

    

 

(e)       Upon
the Payment in Full of the Obligations, (i) this Agreement and the security interests created hereby shall terminate and all rights
to the Collateral shall revert to the respective Grantor that granted such security interests hereunder, and (ii) the Collateral
Agent will, upon any Grantor’s request and at such Grantor’s expense, (A) return to such Grantor such of the Collateral
as shall not have been sold or otherwise disposed of or applied pursuant to the terms hereof and (B) execute and deliver to such
Grantor such documents as such Grantor shall reasonably request to evidence such termination, all without any representation,
warranty or recourse whatsoever.

 

(f)       Governing
Law; Jurisdiction; Jury Trial.

 

(i)       All
questions concerning the construction, validity, enforcement and interpretation of this Agreement shall be governed exclusively
by the internal laws of the State of New York, without giving effect to any choice of law or conflict of law provision or rule
(whether of the State of New York or any other jurisdictions) that would cause the application of the laws of any jurisdictions
other than the State of New York.

 

(ii)      Each
Grantor hereby irrevocably submits to the exclusive jurisdiction of the state and federal courts sitting in The City of New York,
Borough of Manhattan, for the adjudication of any dispute hereunder or in connection herewith or under any of the other Transaction
Documents or with any transaction contemplated hereby or thereby, and hereby irrevocably waives, and agrees not to assert in any
suit, action or proceeding, any claim, defense or objection that it is not personally subject to the jurisdiction of any such
court, that such suit, action or proceeding is brought in an inconvenient forum or that the venue of such suit, action or proceeding
is improper. Each party hereby irrevocably waives personal service of process and consents to process being served in any such
suit, action or proceeding by mailing a copy thereof to such party at the address for such notices to it under Section 9(f) of
the Securities Purchase Agreement and agrees that such service shall constitute good and sufficient service of process and notice
thereof. Nothing contained herein shall be deemed to limit in any way any right to serve process in any manner permitted by law.
Nothing contained herein shall be deemed or operate to preclude the Collateral Agent or the Noteholders from bringing suit or
taking other legal action against any Grantor in any other jurisdiction to collect on a Grantor’s obligations or to enforce
a judgment or other court ruling in favor of the Collateral Agent or a Noteholder.

 

    	 	31	 

     

    

 

(iii)       WAIVER
OF JURY TRIAL, ETC. EACH GRANTOR IRREVOCABLY WAIVES ANY RIGHT IT MAY HAVE TO, AND AGREES NOT TO REQUEST, A JURY TRIAL FOR
THE ADJUDICATION OF ANY DISPUTE HEREUNDER OR UNDER ANY OTHER TRANSACTION DOCUMENT OR IN CONNECTION WITH OR ARISING OUT OF THIS
AGREEMENT, ANY OTHER TRANSACTION DOCUMENT OR ANY TRANSACTION CONTEMPLATED HEREBY OR THEREBY.

 

(iv)       Each
Grantor irrevocably and unconditionally waives any right it may have to claim or recover in any legal action, suit or proceeding
referred to in this Section any special, exemplary, indirect, incidental, punitive or consequential damages.

 

(g)       Section
headings herein are included for convenience of reference only and shall not constitute a part of this Agreement for any other
purpose.

 

(h)       This
Agreement may be executed in any number of counterparts and by different parties hereto in separate counterparts, each of which
shall be deemed to be an original, but all of which taken together constitute one and the same Agreement. Delivery of any executed
counterpart of a signature page of this Agreement by pdf, facsimile or other electronic transmission shall be effective as delivery
of a manually executed counterpart of this Agreement.

 

(i)       This
Agreement shall continue to be effective or be reinstated, as the case may be, if at any time any payment of any of the Obligations
is rescinded or must otherwise be returned by the Collateral Agent, any Noteholder or any other Person (upon (i) the occurrence
of any Insolvency Proceeding of any of the Parent or any Grantor or (ii) otherwise, in all cases as though such payment had not
been made).

 

SECTION 11. Material
Non-Public Information. Upon receipt or delivery by the Parent of any notice in accordance with the terms of this Agreement,
unless the Parent has in good faith determined that the matters relating to such notice do not constitute material, non-public
information relating to the Parent or any of its Subsidiaries, the Parent shall within one (1) Business Day after any such receipt
or delivery publicly disclose such material, non-public information on a Current Report on Form 8-K or otherwise. In the event
that the Parent believes that a notice contains material, non-public information relating to the Parent or any of its Subsidiaries,
the Parent so shall indicate to the Collateral Agent and any applicable Noteholder contemporaneously with delivery of such notice,
and in the absence of any such indication, the Collateral Agent and each Noteholder shall be allowed to presume that all matters
relating to such notice do not constitute material, non-public information relating to the Parent or its Subsidiaries. Nothing
contained in this Section 11 shall limit any obligations of the Parent, or any rights of the Collateral Agent or any Noteholder,
under Section 4(i) of the Securities Purchase Agreement.

 

[REMAINDER OF THIS PAGE INTENTIONALLY
LEFT BLANK]

 

    	 	32	 

     

    

 

IN WITNESS WHEREOF,
each Grantor has caused this Agreement to be executed and delivered by its officer thereunto duly authorized, as of the date first
above written.

 

	 	GRANTORS:
	 	 	 
	 	ICAGEN,
    INC.,
	 	a
    Delaware corporation
	 	 	 
	 	By:	/s/ Richard Cunningham
	 	 	Name:
    Richard Cunningham
	 	 	Title:
    President and CEO
	 	 	 
	 	ICAGEN
    CORP (FORMERLY KNOWN AS XRPRO CORP.)., a Nevada corporation
	 	 	 
	 	By:	/s/ Richard Cunningham
	 	 	Name:
    Richard Cunningham
	 	 	Title:
    President and CEO
	 	 	 
	 	ICAGEN-T
    INC., a Delaware corporation
	 	 	 
	 	By:	/s/ Richard Cunningham
	 	 	Name:
    Richard Cunningham
	 	 	Title:
    President and CEO
	 	 	 
	 	CALDERA
    DISCOVERY, INC, a Delaware corporation
	 	 	 
	 	By:	/s/ Richard Cunningham
	 	 	Name:
    Richard Cunningham
	 	 	Title:
    President and CEO
	 	 	 
	 	XRPRO
    SCIENCES, INC., a Delaware corporation
	 	 	 
	 	By:	/s/ Richard Cunningham
	 	 	Name:
    Richard Cunningham
	 	 	Title:
    President and CEO

 

	ACCEPTED
    BY:	 
	 	 	 
	GPB
    Debt Holdings II, LLC,	 
	as
    Collateral Agent	 
		

         
	 
	By: 	/s/  David
    Gentile	 
	 	Name: David
    Gentile	 
	 	Title:
    Manager	 

 

    	 	33	 

     

    

 

LIST OF EXHIBITS AND SCHEDULES
TO SECURITY AND PLEDGE AGREEMENT

 

A. EXHIBITS

 

Exhibit A – IP Security Agreement

 

B. SCHEDULES

 

Schedule I – Controlled Accounts Etc.

 

Schedule II – Copyrights, Etc.

 

Schedule III – Patents, Etc.

 

Schedule IV – Pledged Entities

 

Schedule V – Trademark Licenses

 

Schedule V(a) – Trademarks, Etc.

 

Schedule VI – Commercial Tort Claims

 

Schedule VII – Legal Names, Organizational Identification
Numbers; States or Jurisdiction of Organization

 

Schedule VIII – Locations

 

Schedule IX – Securities Etc. of each Grantor

 

Schedule X – Licenses, Etc.

 

Schedule XI – All Intellectual Property and Licenses
of Grantors

 

Schedule XII – Pledged Collateral

 

Schedule XIII – [RESERVED]

 

Schedule XIV – [RESERVED]

 

Schedule XV - Pledged Equity

 

Schedule XVI – Locations of Collateral

 

Schedule XVII – Licenses, Etc.

 

Schedule XVIII – Notices. Etc., Re: Exercise of
Rights by certain parties under Licenses

 

Schedule XIX – No Termination Etc. of Licenses

 

     

     

    

 

Execution Version

 

EXHIBIT A

 

FORM OF INTELLECTUAL PROPERTY
SECURITY AGREEMENT 

 

INTELLECTUAL PROPERTY SECURITY AGREEMENT

 

This INTELLECTUAL
PROPERTY SECURITY AGREEMENT (as amended, modified, supplemented, renewed, restated or replaced from time to time, this “IP
Security Agreement”), dated May 15, 2017, is made by the Persons listed on the signature pages hereof (collectively,
the “Grantors”) in favor of GPB Debt Holdings II, LLC, in its capacity as collateral agent (the “Collateral
Agent”) for itself as a Noteholder and any other Noteholders. All capitalized terms not otherwise defined herein (or
as indicated herein as being defined in another document, agreement and/or instrument) shall have the meanings respectively ascribed
thereto in the Security Agreement (as defined below).

 

WHEREAS, Icagen,
Inc., a Delaware corporation with offices located at 4222 Emperor Blvd., Suite 350, Research Triangle Park, Durham, NC, 27703
(the “Parent”), Icagen-T, Inc., a Delaware corporation and a wholly-owned Subsidiary of the Parent with offices
located at 2090 E. Innovation Park Drive, Oro Valley, Arizona 85755 (“ICA-T”) and GPB Debt Holdings II, LLC,
as investor (the “Buyer”) are parties to that certain Securities Purchase Agreement, dated May 15, 2017, pursuant
to which ICA-T and the Parent shall be required to sell, and the Buyer shall purchase or have the right to purchase, the ICA-T
Note (as defined therein) and the Parent Note and Parent Warrant (both terms as defined therein) from ICA-T and the Parent, respectively;

 

WHEREAS, it is
a condition precedent to the purchase of the ICA-T Note and the Parent Note and Parent Warrants under the Securities Purchase
Agreement that each Grantor has executed and delivered that certain Security and Pledge Agreement, dated May 15, 2017, made by
the Grantors to the Collateral Agent (as amended, modified, supplemented, renewed, restated or replaced from time to time, the
“Security Agreement”); and

 

WHEREAS, under
the terms of the Security Agreement, the Grantors have granted to the Collateral Agent, for the benefit of the Noteholders, a
security interest in, among other property, certain intellectual property and Licenses of the Grantors, and have agreed as a condition
thereof to execute this IP Security Agreement for recording with the U.S. Patent and Trademark Office and the United States Copyright
Office; and

 

WHEREAS, the
Grantors have determined that the execution, delivery and performance of this IP Security Agreement directly benefits, and is
in the best interest of, the Grantors.

 

NOW, THEREFORE,
in consideration of the premises and the agreements herein and for such other good and valuable consideration, the receipt and
sufficiency of which is hereby acknowledged, and in order to induce the Buyer to perform under the Securities Purchase Agreement,
each Grantor agrees with the Collateral Agent, for the benefit of the Noteholders, as follows

 

SECTION 1. Grant
of Security. Each Grantor hereby grants to the Collateral Agent for the benefit of the Collateral Agent as a Noteholder and
any other Noteholders a security interest in all of such Grantor’s right, title and interest in and to the following (the
“Collateral”):

 

(i)       the
United States Patents and Patent applications set forth in Schedule A hereto;

 

     

     

    

 

(ii)       the
United States Trademarks and service mark registrations and applications set forth in Schedule B hereto (provided that
no security interest shall be granted in United States intent-to-use trademark applications to the extent that, and solely during
the period in which, the grant of a security interest therein would impair the validity or enforceability of such intent-to-use
trademark applications under applicable federal law), together with the goodwill symbolized thereby;

 

(iii)      all
United States Copyrights, whether registered or unregistered, now owned or hereafter acquired by such Grantor, including, without
limitation, the copyright registrations and applications and exclusive copyright licenses set forth in Schedule C hereto;

 

(iv)      all
reissues, divisions, continuations, continuations-in-part, extensions, renewals and reexaminations of any of the foregoing, all
rights in the foregoing provided by international treaties or conventions, all rights corresponding thereto throughout the world
and all other rights of any kind whatsoever of such Grantor accruing thereunder or pertaining thereto;

 

(v)       any
and all claims for damages and injunctive relief for past, present and future infringement, dilution, misappropriation, violation,
misuse or breach with respect to any of the foregoing, with the right, but not the obligation, to sue for and collect, or otherwise
recover, such damages; and

 

(vi)       any
and all proceeds of, collateral for, income, royalties and other payments now or hereafter due and payable with respect to, and
supporting obligations relating to, any and all of the Collateral of or arising from any of the foregoing.

 

SECTION 2. Security
for Obligations. The grant of a security interest in, the Collateral under this IP Security Agreement by each Grantor) secures
the payment of all Obligations of each Grantor now or hereafter existing under or in respect of the ICA-T Note and the other Transaction
Documents, whether direct or indirect, absolute or contingent, and whether for principal, reimbursement obligations, interest,
redemption payments, premiums, penalties, fees, indemnifications, contract causes of action, costs, expenses or otherwise.

 

SECTION 3. Recordation.
Each Grantor authorizes and requests that the Register of Copyrights, the Commissioner for Patents and the Commissioner for Trademarks
and any other applicable government officer record this IP Security Agreement.

 

SECTION 4. Execution
in Counterparts. This IP Security Agreement may be executed in any number of counterparts, each of which when so executed
shall be deemed to be an original and all of which taken together shall constitute one and the same agreement.

 

SECTION 5. Grants,
Rights and Remedies. This IP Security Agreement has been entered into in conjunction with the provisions of the Security Agreement.
Each Grantor does hereby acknowledge and confirm that the grant of the security interest hereunder to, and the rights and remedies
of, the Collateral Agent with respect to the Collateral are more fully set forth in the Security Agreement, the terms and provisions
of which are incorporated herein by reference as if fully set forth herein.

 

    	 	2	 

     

    

 

SECTION
6. Governing Law; Jurisdiction; Jury Trial.

 

(i)       All
questions concerning the construction, validity, enforcement and interpretation of this Agreement shall be governed by the internal
laws of the State of New York, without giving effect to any choice of law or conflict of law provision or rule (whether of the
State of New York or any other jurisdictions) that would cause the application of the laws of any jurisdictions other than the
State of New York.

 

(ii)       Each
Grantor hereby irrevocably submits to the exclusive jurisdiction of the state and federal courts sitting in The City of New York,
Borough of Manhattan, for the adjudication of any dispute hereunder or in connection herewith or under any of the other Transaction
Documents or with any transaction contemplated hereby or thereby, and hereby irrevocably waives, and agrees not to assert in any
suit, action or proceeding, any claim, defense or objection that it is not personally subject to the jurisdiction of any such
court, that such suit, action or proceeding is brought in an inconvenient forum or that the venue of such suit, action or proceeding
is improper. Each party hereby irrevocably waives personal service of process and consents to process being served in any such
suit, action or proceeding by mailing a copy thereof to such party at the address for such notices to it under Section 9(f) of
the Securities Purchase Agreement and agrees that such service shall constitute good and sufficient service of process and notice
thereof. Nothing contained herein shall be deemed to limit in any way any right to serve process in any manner permitted by law.
Nothing contained herein shall be deemed or operate to preclude the Collateral Agent or the Noteholders from bringing suit or
taking other legal action against any Grantor in any other jurisdiction to collect on a Grantor’s obligations or to enforce
a judgment or other court ruling in favor of the Collateral Agent or a Noteholder.

 

(iii)      WAIVER
OF JURY TRIAL, ETC. EACH GRANTOR IRREVOCABLY WAIVES ANY RIGHT IT MAY HAVE TO, AND AGREES NOT TO REQUEST, A JURY TRIAL FOR
THE ADJUDICATION OF ANY DISPUTE HEREUNDER OR UNDER ANY OTHER TRANSACTION DOCUMENT OR IN CONNECTION WITH OR ARISING OUT OF THIS
AGREEMENT, ANY OTHER TRANSACTION DOCUMENT OR ANY TRANSACTION CONTEMPLATED HEREBY OR THEREBY.

 

(iv)      Each
Grantor irrevocably and unconditionally waives any right it may have to claim or recover in any legal action, suit or proceeding
referred to in this Section any special, exemplary, indirect, incidental, punitive or consequential damages.

 

[The remainder of the page is intentionally
left blank]

 

    	 	3	 

     

    

 

IN WITNESS WHEREOF,
each Grantor has caused this Agreement to be duly executed and delivered by its officer thereunto duly authorized as of the date
first above written.

 

	 	GRANTORS:
	 	 	 
	 	ICAGEN,
    INC.,
	 	a
    Delaware corporation
	 	 	 
	 	By:	
	 	 	Name:
    Richard Cunningham
	 	 	Title:
    President and CEO
	 	 	 
	 	ICAGEN
    CORP. (FORMERLY KNOWN AS XRPRO CORP., FORMERLY KNOWN AS CALDERA
    PHARMACEUTICALS, INC.),
    a Nevada corporation
	 	 	 
	 	By:	
	 	 	Name: Richard Cunningham
	 	 	Title: President and
    CEO
	 	 	 
	 	ICAGEN-T
    INC., a Delaware corporation
	 	 	 
	 	By:	
	 	 	Name: Richard Cunningham
	 	 	Title: President and
    CEO
	 	 	 
	 	CALDERA
    DISCOVERY, INC, a Delaware corporation
	 	 	 
	 	By:	
	 	 	Name:
    Richard Cunningham
	 	 	Title:
    President and CEO
	 	 	 
	 	XRPRO
    SCIENCES, INC., a Delaware corporation
	 	 	 
	 	By:	
	 	 	Name:
    Richard Cunningham
	 	 	Title:
    President and CEO

 

    	 	4	 

     

    

 

SCHEDULE I

 

Controlled Accounts Etc.

 

	 	Icagen Inc.	 
	 	 	 
	 	 #####	 #####	 
	 	 	 	 
	 	Icagen Corp.	 
	 	 	 
	 	##### 	##### 	 
	 	 	 	 
	 	Icagen-T, Inc.	 
	 	 	 
	 	##### 	##### 	 

 

Accounts to be closed within 90
days of conclusion of Agreement:

 

Icagen Inc.

 

	 	 #####	 #####	 
	 	 	 	 
	 	 #####	 #####	 
	 	 	 	 
	 	 #####	 #####	 
	 	 	 	 
	 	 #####	##### 	 
	 	 	 	 
	 	 #####	 #####	 

 

     

     

    

 

SCHEDULE II

 

Copyrights, Etc.

 

None

 

 

 

 

 

 

 

 

 

 

 

     

     

    

 

SCHEDULE III

 

Patents, Etc.

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-001	 	METHOD FOR DETECTING BINDING EVENTS USING MICRO-X-RAY FLUORESCENCE SPECTROMETRY	 	United States	 	09/859,701	 	2003-0027129	 	7,858,385	 	Patented
	ICA-002EP	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Europe	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002BE	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Belgium	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002CH	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Switzerland	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002DE	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Germany	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002DK	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Denmark	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002ES	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Spain	 	3748920	 	1525458	 	1525458	 	Patented

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-002FI	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Finland	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002FR	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	France	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002GB	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	United Kingdom	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002IT	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Italy	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002SE	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Sweden	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002NL	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Netherlands	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002JP	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Japan	 	2004-524531	 	2006-503268	 	4560403	 	Patented
	ICA-002SG	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Singapore	 	200500360-3	 	109345	 	109345	 	Patented

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-002C2	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	United States	 	11/444,660	 	2007-0003008	 	7,519,145	 	Patented
	ICA-002C3	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	United States	 	12/396,592	 	2009-0175410	 	7,929,662	 	Patented
	ICA-003EP	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	Europe	 	4755687.3	 	1644095	 	1644095	 	Patented
	ICA-003CH	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	Switzerland/ 
Liechtenstein	 	4755687.3	 	1644095	 	1644095	 	Patented
	ICA-003DE	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	Germany	 	4755687.3	 	1644095	 	1644095	 	Patented
	ICA-003FR	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	France	 	4755687.3	 	1644095	 	1644095	 	Patented
	ICA-003GB	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	United Kingdom	 	4755687.3	 	1644095	 	1644095	 	Patented
	ICA-003IE	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	Ireland	 	4755687.3	 	1644095	 	1644095	 	Patented
	ICA-003NL	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	Netherlands	 	4755687.3	 	1644095	 	1644095	 	Patented
	ICA-003JP	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	Japan	 	2006-520181	 	2007527524	 	4782676	 	Patented

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-003SG	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	Singapore	 	2005085584	 	 	 	118682	 	Patented
	ICA-003	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	United States	 	10/621,825	 	2005-0011818	 	6,858,148	 	Patented
	ICA-003C1	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	United States	 	10/986,519	 	2005-0095636	 	7,241,381	 	Patented
	ICA-004	 	DRUG DEVELOPMENT AND MANUFACTURING	 	United States	 	10/880,388	 	2004-0235059	 	9,157,875	 	Patented
	ICA-005EP	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Europe	 	7874491.9	 	2084519	 	2084519	 	Patented
	ICA-005CH	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Switzerland/ 
Liechtenstein	 	07 874 491.9	 	2084519	 	2084519	 	Patented
	ICA-005DE	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Germany	 	60 2007 024 468.4	 	2084519	 	608007024468.4	 	Patented
	ICA-005DK	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Denmark	 	07 874 491.9	 	2084519	 	2084519	 	Patented
	ICA-005FR1	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	France	 	07 874 491.9	 	2084519	 	2084519	 	Patented
	ICA-005GB	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	United Kingdom	 	7874491.9	 	2084519	 	2084519	 	Patented
	ICA-005HK	 	ADVANCED DRUG DEVELOPMENT AND MANUFACTURING	 	Hong Kong (via EP -005EPDV)	 	13104259.3	 	1177280	 	1177280	 	Patented
	ICA-005IE	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Ireland	 	7874491.9	 	1177280	 	2084519	 	Patented

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-005IT	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Italy	 	7874491.9	 	1177280	 	2084519	 	Patented
	ICA-005NL	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Netherlands	 	7874491.9	 	1177280	 	2084519	 	Patented
	ICA-005SE	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Sweden	 	7874491.9	 	1177280	 	2084519	 	Patented
	ICA-005EPDV	 	X-RAY MICROSCOPE	 	Europe	 	12164870.3	 	2511844	 	2511844	 	Patented
	ICA-005CHDV	 	X-RAY MICROSCOPE	 	Switzerland and Lichtenstein	 	12164870.3	 	2511844	 	2511844	 	Patented
	ICA-005DEDV	 	X-RAY MICROSCOPE	 	Germany	 	12164870.3	 	2511844	 	602007042616.2	 	Patented
	ICA-005FRDV	 	X-RAY MICROSCOPE	 	France	 	12164870.3	 	2511844	 	2511844	 	Patented
	ICA-005GBDV	 	X-RAY MICROSCOPE	 	United Kingdom	 	12164870.3	 	2511844	 	2511844	 	Patented
	ICA-005HK	 	ADVANCED DRUG DEVELOPMENT AND MANUFACTURING	 	Hong Kong (via EP -005EPDV)	 	2013104259.3	 	1177280	 	1177280	 	Patented
	ICA-005IEDV	 	X-RAY MICROSCOPE	 	Ireland	 	12164870.3	 	2511844	 	2511844	 	Patented
	ICA-005JP	 	ADVANCED DRUG DEVELOPMENT AND MANUFACTURING	 	Japan	 	2009-532446	 	2010509566	 	5143841	 	Patented
	ICA-005JPDV2	 	ADVANCED DRUG DEVELOPMENT AND MANUFACTURING	 	Japan	 	2014-123249	 	2014-123249	 	5913441	 	Patented
	ICA-005C1	 	ADVANCED DRUG DEVELOPMENT AND MANUFACTURING	 	United States	 	14/693,094	 	2015-0309021	 	N/A	 	Pending

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-006EP	 	WELL PLATE	 	Europe	 	8798006.6	 	2183644	 	2183644	 	Patented
	ICA-006BE	 	WELL PLATE	 	Belgium	 	8798007.6	 	2183644	 	2183644	 	Patented
	ICA-006CH	 	WELL PLATE	 	Switzerland	 	8798008.6	 	2183644	 	2183644	 	Patented
	ICA-006DE	 	WELL PLATE	 	Germany	 	8798009.6	 	2183644	 	602008044640.9	 	Patented
	ICA-006DK	 	WELL PLATE	 	Denmark	 	8798010.6	 	2183644	 	2183644	 	Patented
	ICA-006ES	 	WELL PLATE	 	Spain	 	8798011.6	 	2183644	 	2183644	 	Patented
	ICA-006FI	 	WELL PLATE	 	Finland	 	8798012.6	 	2183644	 	2183644	 	Patented
	ICA-006FR	 	WELL PLATE	 	France	 	8798013.6	 	2183644	 	2183644	 	Patented
	ICA-006GB	 	WELL PLATE	 	United Kingdom	 	8798014.6	 	2183644	 	2183644	 	Patented
	ICA-006IE	 	WELL PLATE	 	Ireland	 	8798015.6	 	2183644	 	2183644	 	Patented
	ICA-006IT	 	WELL PLATE	 	Italy	 	8798016.6	 	2183644	 	2183644	 	Patented
	ICA-006 NL	 	WELL PLATE	 	Netherlands	 	8798017.6	 	2183644	 	2183644	 	Patented
	ICA-006NO	 	WELL PLATE	 	Norway	 	8798018.6	 	2183644	 	2183644	 	Patented
	ICA-006SE	 	WELL PLATE	 	Sweden	 	8798019.6	 	2183644	 	2183644	 	Patented
	ICA-006JP	 	WELL PLATE	 	Japan	 	2010-521206	 	2010537171	 	5628035	 	Patented
	ICA-006JPDV	 	WELL PLATE	 	Japan	 	2013-117600	 	2013224946	 	5755682	 	Patented
	ICA-006JPDV2	 	WELL PLATE	 	Japan	 	2014-202871	 	2015004692	 	6076308	 	Patented
	ICA-006	 	WELL PLATE	 	United States	 	12/192,762	 	2009-0046832	 	8,238,515	 	Patented
	ICA-006C1	 	WELL PLATE	 	United States	 	13/567,613	 	2013-0034205	 	8,873,707	 	Patented
	ICA-006C2	 	WELL PLATE	 	United States	 	14/508,322	 	2015-0023467	 	9,476,846	 	Patented
	ICA-006C3	 	WELL PLATE	 	United States	 	15/273,767	 	2017-0010228	 	N/A	 	Pending
	ICA-007JP	 	METHOD AND APPARATUS FOR MEASURING PROTEIN POST-TRANSLATIONAL MODIFICATION	 	Japan	 	2010-5272	 	2010539944	 	5743135	 	Patented

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-007JPDV1	 	METHOD AND APPARATUS FOR MEASURING PROTEIN POST-TRANSLATIONAL MODIFICATION	 	Japan	 	2014-221166	 	2015033386	 	N/A	 	Pending
	ICA-007C1/XR7-US2	 	METHOD AND APPARATUS FOR MEASURING PROTEIN POST-TRANSLATIONAL MODIFICATION	 	United States	 	15/052,914	 	2016-0201111	 	N/A	 	Pending
	ICA-008CN	 	METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS	 	China	 	200980125952.3	 	102083365	 	ZL 200980125952.3	 	Patented
	ICA-008CNDV	 	METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS	 	China	 	201310298029.8	 	103411988	 	2077368	 	Patented
	ICA-008CNDV2	 	METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS	 	China	 	201510083796.6	 	N/A	 	N/A	 	Pending
	ICA-008EP	 	METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS	 	Europe	 	09774467.6	 	2306897	 	N/A	 	Allowed
	ICA-008HK	 	METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS	 	Hong Kong	 	11112984.0	 	1158478	 	1158478	 	Patented

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-008	 	METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING X-RAY FLUORESCENCE	 	United States	 	12/496,532	 	2010-0003697	 	8,431,357	 	Patented
	ICA-008C1	 	METHOD FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING X-RAY FLUORESCENCE USING X-RAY FLUORESCENCE	 	United States	 	13/871,697	 	2013-0236887	 	9,063,154	 	Patented
	ICA-008C2	 	METHOD FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING X-RAY FLUORESCENCE	 	United States	 	14/669,923	 	2015-0198615	 	9,506,931	 	Patented
	ICA-008C3	 	METHOD FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING X-RAY FLUORESCENCE	 	United States	 	15/334,854	 	2017-0045530	 	N/A	 	Pending
	ICA-009	 	METHOD FOR ANALYSIS USING X-RAY FLUORESCENCE	 	United States	 	13/317,341	 	2012-0093286	 	9,063,066	 	Patented
	ICA-009C1	 	METHOD FOR ANALYSIS USING X-RAY FLUORESCENCE	 	United States	 	14/715,206	 	2015-0276631	 	9,435,756	 	Patented
	ICA-009C2	 	METHOD FOR ANALYSIS USING X-RAY FLUORESCENCE	 	United States	 	14/715,218	 	2015-0276632	 	9,442,085	 	Patented
	ICA-009C3	 	METHOD FOR ANALYSIS USING X-RAY FLUORESCENCE	 	United States	 	14/715,233	 	2015-0260664	 	9,335,284	 	Patented
	ICA-009C4	 	METHOD FOR ANALYSIS USING X-RAY FLUORESCENCE	 	United States	 	15/227,292	 	2016-0341678	 	N/A	 	Pending
	ICA-010PC	 	METHODS AND APPARATUS FOR MEASURING METALS AND METALLOIDS	 	International	 	PCT/US17/28064	 	N/A	 	N/A	 	Pending

 

     

     

    

 

SCHEDULE IV

 

Pledged Entities

 

Icagen Corp.

 

XRpro Sciences, Inc.

 

Caldera Discovery, Inc.

 

 

 

 

 

 

 

 

 

 

     

     

    

 

SCHEDULE V

 

Trademark Licenses

 

None

 

 

 

 

 

 

 

 

 

     

     

    

 

SCHEDULE V(a)

 

Trademarks, Etc.

 

 

     

     

    

 

 

 

     

     

    

 

 

 

     

     

    

 

SCHEDULE VI

 

Commercial Tort Claims

 

None

 

 

 

 

 

 

 

 

 

 

 

     

     

    

 

SCHEDULE VII

 

Legal Names, Organizational
Identification Numbers; States or Jurisdiction of Organization

 

	Grantor’s Name	 	State of Organization	 	Federal Employer I.D.	 	Organizational I.D.
	Icagen, Inc. (formerly known as; Caldera Pharmaceuticals, Inc.; and XRpro Sciences, Inc.	 	Delaware North Carolina	 	#####	 	3723366
	Icagen Corp. (formerly known as XRpro Corp.)	 	Nevada North Carolina   	 	#####	 	NV20101523783
	Caldera Discovery, Inc.	 	Delaware 	 	#####	 	5717856
	XRpro Sciences, Inc.	 	 Delaware 	 	#####	 	5904530
	Icagen-T, Inc.	 	Delaware Arizona 	 	#####	 	6070175

 

     

     

    

 

SCHEDULE VIII

 

Locations

 

Icagen Corp.

4222 Emperor Boulevard, Suite 350

Research Triangle Park

Durham, NC, 27703

 

Icagen-T, Inc.

2090 E. Innovation Park Drive

Tucson, AZ 85755

 

 

 

 

 

 

     

     

    

 

SCHEDULE IX

 

Securities Etc. of each Grantor

 

Securities

 

	Grantor	 	Name of Issuer / Pledged Entity	 	Number
    of Shares	 	Class	 	Certificate
    No.(s)
	Icagen, Inc.	 	Icagen Corp.	 	100,000	 	Common	 	C01
	Icagen, Inc.	 	Caldera Discovery, Inc.	 	100	 	Common	 	C-01
	Icagen, Inc.	 	XRpro Sciences, Inc	 	100	 	Common	 	C-01

 

Deposit Accounts, Securities
Accounts and Commodities Accounts

 

	Grantor	 	Name and Address of Institution	 	Purpose of the Account	 	Account No.
	Icagen Inc.	 	 #####	 	 #####	 	 #####
	 	 	 	 	 	 	 
	Icagen Inc.	 	 #####	 	 #####	 	 #####
	 	 	 	 	 	 	 
	Icagen Inc.	 	 #####	 	 #####	 	 #####
	 	 	 	 	 	 	 
	Icagen Corp.	 	 #####	 	 #####	 	 #####
	 	 	 	 	 	 	 
	Icagen-T, Inc.	 	 #####	 	 #####	 	 #####

 

Foreign Currency Controlled
Accounts

 

None

 

     

     

    

 

SCHEDULE X

 

Licenses, Etc.

 

Radioactive Materials License

 

 

 

 

 

 

 

 

     

     

    

 

SCHEDULE XI

 

All Intellectual Property
of Grantors

 

See Schedule 5(a) and 10

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-001	 	METHOD FOR DETECTING BINDING EVENTS USING MICRO-X-RAY FLUORESCENCE SPECTROMETRY	 	United States	 	09/859,701	 	2003-0027129	 	7,858,385	 	Patented
	ICA-002EP	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Europe	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002BE	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Belgium	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002CH	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Switzerland	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002DE	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Germany	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002DK	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Denmark	 	3748920	 	1525458	 	1525458	 	Patented

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-002ES	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Spain	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002FI	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Finland	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002FR	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	France	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002GB	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	United Kingdom	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002IT	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Italy	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002SE	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Sweden	 	3748920	 	1525458	 	1525458	 	Patented
	ICA-002NL	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Netherlands	 	3748920	 	1525458	 	1525458	 	Patented

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-002JP	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Japan	 	2004-524531	 	2006-503268	 	4560403	 	Patented
	ICA-002SG	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	Singapore	 	200500360-3	 	109345	 	109345	 	Patented
	ICA-002C2	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	United States	 	11/444,660	 	2007-0003008	 	7,519,145	 	Patented
	ICA-002C3	 	FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE	 	United States	 	12/396,592	 	2009-0175410	 	7,929,662	 	Patented
	ICA-003EP	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	Europe	 	4755687.3	 	1644095	 	1644095	 	Patented
	ICA-003CH	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	Switzerland/ 
Liechtenstein	 	4755687.3	 	1644095	 	1644095	 	Patented
	ICA-003DE	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	Germany	 	4755687.3	 	1644095	 	1644095	 	Patented

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-003FR	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	France	 	4755687.3	 	1644095	 	1644095	 	Patented
	ICA-003GB	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	United Kingdom	 	4755687.3	 	1644095	 	1644095	 	Patented
	ICA-003IE	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	Ireland	 	4755687.3	 	1644095	 	1644095	 	Patented
	ICA-003NL	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	Netherlands	 	4755687.3	 	1644095	 	1644095	 	Patented
	ICA-003JP	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	Japan	 	2006-520181	 	2007527524	 	4782676	 	Patented
	ICA-003SG	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	Singapore	 	2005085584	 	 	 	118682	 	Patented
	ICA-003	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	United States	 	10/621,825	 	2005-0011818	 	6,858,148	 	Patented
	ICA-003C1	 	METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING	 	United States	 	10/986,519	 	2005-0095636	 	7,241,381	 	Patented
	ICA-004	 	DRUG DEVELOPMENT AND MANUFACTURING	 	United States	 	10/880,388	 	2004-0235059	 	9,157,875	 	Patented
	ICA-005EP	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Europe	 	7874491.9	 	2084519	 	2084519	 	Patented

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-005CH	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Switzerland/ 
Liechtenstein	 	07 874 491.9	 	2084519	 	2084519	 	Patented
	ICA-005DE	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Germany	 	60 2007 024 468.4	 	2084519	 	608007024468.4	 	Patented
	ICA-005DK	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Denmark	 	07 874 491.9	 	2084519	 	2084519	 	Patented
	ICA-005FR1	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	France	 	07 874 491.9	 	2084519	 	2084519	 	Patented
	ICA-005GB	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	United Kingdom	 	7874491.9	 	2084519	 	2084519	 	Patented
	ICA-005HK	 	ADVANCED DRUG DEVELOPMENT AND MANUFACTURING	 	Hong Kong (via EP -005EPDV)	 	13104259.3	 	1177280	 	1177280	 	Patented
	ICA-005IE	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Ireland	 	7874491.9	 	1177280	 	2084519	 	Patented
	ICA-005IT	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Italy	 	7874491.9	 	1177280	 	2084519	 	Patented
	ICA-005NL	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Netherlands	 	7874491.9	 	1177280	 	2084519	 	Patented
	ICA-005SE	 	X-RAY FLUORESCENCE ANALYSIS METHOD	 	Sweden	 	7874491.9	 	1177280	 	2084519	 	Patented
	ICA-005EPDV	 	X-RAY MICROSCOPE	 	Europe	 	12164870.3	 	2511844	 	2511844	 	Patented
	ICA-005CHDV	 	X-RAY MICROSCOPE	 	Switzerland and Lichtenstein	 	12164870.3	 	2511844	 	2511844	 	Patented
	ICA-005DEDV	 	X-RAY MICROSCOPE	 	Germany	 	12164870.3	 	2511844	 	602007042616.2	 	Patented

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-005FRDV	 	X-RAY MICROSCOPE	 	France	 	12164870.3	 	2511844	 	2511844	 	Patented
	ICA-005GBDV	 	X-RAY MICROSCOPE	 	United Kingdom	 	12164870.3	 	2511844	 	2511844	 	Patented
	ICA-005HK	 	ADVANCED DRUG DEVELOPMENT AND MANUFACTURING	 	Hong Kong (via EP -005EPDV)	 	2013104259.3	 	1177280	 	1177280	 	Patented
	ICA-005IEDV	 	X-RAY MICROSCOPE	 	Ireland	 	12164870.3	 	2511844	 	2511844	 	Patented
	ICA-005JP	 	ADVANCED DRUG DEVELOPMENT AND MANUFACTURING	 	Japan	 	2009-532446	 	2010509566	 	5143841	 	Patented
	ICA-005JPDV2	 	ADVANCED DRUG DEVELOPMENT AND MANUFACTURING	 	Japan	 	2014-123249	 	2014-123249	 	5913441	 	Patented
	ICA-005C1	 	ADVANCED DRUG DEVELOPMENT AND MANUFACTURING	 	United States	 	14/693,094	 	2015-0309021	 	N/A	 	Pending
	ICA-006EP	 	WELL PLATE	 	Europe	 	8798006.6	 	2183644	 	2183644	 	Patented
	ICA-006BE	 	WELL PLATE	 	Belgium	 	8798007.6	 	2183644	 	2183644	 	Patented
	ICA-006CH	 	WELL PLATE	 	Switzerland	 	8798008.6	 	2183644	 	2183644	 	Patented
	ICA-006DE	 	WELL PLATE	 	Germany	 	8798009.6	 	2183644	 	602008044640.9	 	Patented
	ICA-006DK	 	WELL PLATE	 	Denmark	 	8798010.6	 	2183644	 	2183644	 	Patented
	ICA-006ES	 	WELL PLATE	 	Spain	 	8798011.6	 	2183644	 	2183644	 	Patented
	ICA-006FI	 	WELL PLATE	 	Finland	 	8798012.6	 	2183644	 	2183644	 	Patented
	ICA-006FR	 	WELL PLATE	 	France	 	8798013.6	 	2183644	 	2183644	 	Patented
	ICA-006GB	 	WELL PLATE	 	United Kingdom	 	8798014.6	 	2183644	 	2183644	 	Patented
	ICA-006IE	 	WELL PLATE	 	Ireland	 	8798015.6	 	2183644	 	2183644	 	Patented
	ICA-006IT	 	WELL PLATE	 	Italy	 	8798016.6	 	2183644	 	2183644	 	Patented
	ICA-006 NL	 	WELL PLATE	 	Netherlands	 	8798017.6	 	2183644	 	2183644	 	Patented

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-006NO	 	WELL PLATE	 	Norway	 	8798018.6	 	2183644	 	2183644	 	Patented
	ICA-006SE	 	WELL PLATE	 	Sweden	 	8798019.6	 	2183644	 	2183644	 	Patented
	ICA-006JP	 	WELL PLATE	 	Japan	 	2010-521206	 	2010537171	 	5628035	 	Patented
	ICA-006JPDV	 	WELL PLATE	 	Japan	 	2013-117600	 	2013224946	 	5755682	 	Patented
	ICA-006JPDV2	 	WELL PLATE	 	Japan	 	2014-202871	 	2015004692	 	6076308	 	Patented
	ICA-006	 	WELL PLATE	 	United States	 	12/192,762	 	2009-0046832	 	8,238,515	 	Patented
	ICA-006C1	 	WELL PLATE	 	United States	 	13/567,613	 	2013-0034205	 	8,873,707	 	Patented
	ICA-006C2	 	WELL PLATE	 	United States	 	14/508,322	 	2015-0023467	 	9,476,846	 	Patented
	ICA-006C3	 	WELL PLATE	 	United States	 	15/273,767	 	2017-0010228	 	N/A	 	Pending
	ICA-007JP	 	METHOD AND APPARATUS FOR MEASURING PROTEIN POST-TRANSLATIONAL MODIFICATION	 	Japan	 	2010-5272	 	2010539944	 	5743135	 	Patented
	ICA-007JPDV1	 	METHOD AND APPARATUS FOR MEASURING PROTEIN POST-TRANSLATIONAL MODIFICATION	 	Japan	 	2014-221166	 	2015033386	 	N/A	 	Pending
	ICA-007C1/XR7-US2	 	METHOD AND APPARATUS FOR MEASURING PROTEIN POST-TRANSLATIONAL MODIFICATION	 	United States	 	15/052,914	 	2016-0201111	 	N/A	 	Pending

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-008CN	 	METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS	 	China	 	200980125952.3	 	102083365	 	ZL 200980125952.3	 	Patented
	ICA-008CNDV	 	METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS	 	China	 	201310298029.8	 	103411988	 	2077368	 	Patented
	ICA-008CNDV2	 	METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS	 	China	 	201510083796.6	 	N/A	 	N/A	 	Pending
	ICA-008EP	 	METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS	 	Europe	 	09774467.6	 	2306897	 	N/A	 	Allowed
	ICA-008HK	 	METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS	 	Hong Kong	 	11112984.0	 	1158478	 	1158478	 	Patented
	ICA-008	 	METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING X-RAY FLUORESCENCE	 	United States	 	12/496,532	 	2010-0003697	 	8,431,357	 	Patented
	ICA-008C1	 	METHOD FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING X-RAY FLUORESCENCE USING X-RAY FLUORESCENCE	 	United States	 	13/871,697	 	2013-0236887	 	9,063,154	 	Patented

 

     

     

    

 

	Reference	 	Title	 	Country	 	Application No.	 	Pub. No.	 	Patent No.	 	Status
	ICA-008C2	 	METHOD FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING X-RAY FLUORESCENCE	 	United States	 	14/669,923	 	2015-0198615	 	9,506,931	 	Patented
	ICA-008C3	 	METHOD FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING X-RAY FLUORESCENCE	 	United States	 	15/334,854	 	2017-0045530	 	N/A	 	Pending
	ICA-009	 	METHOD FOR ANALYSIS USING X-RAY FLUORESCENCE	 	United States	 	13/317,341	 	2012-0093286	 	9,063,066	 	Patented
	ICA-009C1	 	METHOD FOR ANALYSIS USING X-RAY FLUORESCENCE	 	United States	 	14/715,206	 	2015-0276631	 	9,435,756	 	Patented
	ICA-009C2	 	METHOD FOR ANALYSIS USING X-RAY FLUORESCENCE	 	United States	 	14/715,218	 	2015-0276632	 	9,442,085	 	Patented
	ICA-009C3	 	METHOD FOR ANALYSIS USING X-RAY FLUORESCENCE	 	United States	 	14/715,233	 	2015-0260664	 	9,335,284	 	Patented
	ICA-009C4	 	METHOD FOR ANALYSIS USING X-RAY FLUORESCENCE	 	United States	 	15/227,292	 	2016-0341678	 	N/A	 	Pending
	ICA-010PC	 	METHODS AND APPARATUS FOR MEASURING METALS AND METALLOIDS	 	International	 	PCT/US17/28064	 	N/A	 	N/A	 	Pending

 

     

     

    

 

SCHEDULE XII

 

Pledged Collateral

 

	Icagen,
    Inc.	Delaware
    Secretary of State - U.S. Bank Equipment Finance-Equipment
	 	 
	Icagen-T, Inc.

	Arizona, Pima County-Sanofi
        U.S. Services Inc-buildings, improvements and fixtures, rents, leases, issues, profits or income on property located in
        Pima County.
	 	 
	Icagen-T, Inc.

	Arizona Secretary of State-Sanofi
        U.S. Services Inc.-chemical libraries and equipment and movable assets owned by Sanofi U.S. Services Inc.
	 	 
	Icagen-T, Inc.

	Delaware Secretary of State
        - Sanofi U.S. Services Inc.-chemical libraries and equipment and movable assets owned by Sanofi U.S. Services Inc.
	 	 
	Icagen-T, Inc.

	Deed of Trust and Assignment
        of Rents
	 	 
	Icagen-T, Inc.

	

        

        

        Deed of Sale

 

     

     

    

 

SCHEDULE XIII

 

[RESERVED]

 

 

 

 

 

 

 

 

 

     

     

    

 

SCHEDULE XIV

 

[RESERVED]

 

 

 

 

 

 

 

 

 

 

 

 

 

     

     

    

 

SCHEDULE XV

 

Pledged Equity

 

	Icagen Inc.	Icagen Corp.	100,000 common shares	C01
	 	 	 	 
	 	XRpro Sciences, Inc.	1,000 common shares	C-01
	 	 	 	 
	 	Caldera Discovery, Inc.	100 common shares	C-01

 

 

     

     

    

 

SCHEDULE XVI

 

Locations of Collateral 

 

Icagen Inc.

4222 Emperor Boulevard, Suite 350

Research Triangle Park

Durham, NC, 27703

 

Icagen Corp.

4222 Emperor Boulevard, Suite 350

Research Triangle Park

Durham, NC, 27703

 

Icagen-T, Inc.

2090 E Innovation Park Drive

Tucson, AZ 85755

 

 

     

     

    

 

SCHEDULE XVII

 

Licenses, Etc.

 

None

 

     

     

    

 

Schedule XVIII

 

Notices. Etc. Re: Exercise
of Rights by certain parties under Licenses

 

None

 

 

 

     

     

    

 

SCHEDULE XIX

 

No Termination Etc. of Licenses

 

NoneExhibit
10.4

 

Execution
Version

 

GUARANTY
OF OBLIGATIONS OF PARENT

 

This
GUARANTY, dated as of May 15, 2017 (this “Guaranty”), is made by each of the undersigned (each a “Guarantor”,
and collectively, the “Guarantors”), in favor of GPB Debt Holdings II, LLC, a Delaware limited liability company,
in its capacity as collateral agent (in such capacity, the “Collateral Agent” as hereinafter further defined)
for the “Buyer” party to the Securities Purchase Agreement (each as defined below).

 

W
I T N E S S E T H:

 

WHEREAS,
Icagen, Inc., a Delaware corporation with its executive offices located at 4222 Emperor Blvd., Suite 350, Research Triangle Park,
Durham, NC, 27703 (the “Parent”), Icagen-T, Inc., a Delaware corporation and a wholly-owned Subsidiary of the
Parent with its executive offices located at 2090 E. Innovation Park Drive, Oro Valley, Arizona 85755 (“ICA-T”)
and GPB Debt Holdings II, LLC, in its capacity as an investor (the “Buyer”) are parties to the Securities Purchase
Agreement, dated as of May 15, 2017 (as amended, restated, extended, replaced or otherwise modified from time to time and together
with all amendments, supplements and exhibits thereto, collectively, the “Securities Purchase Agreement”),
pursuant to which, among other actions set forth therein, (i) ICA-T shall be required to sell an $8,000,000 aggregate principal
amount senior secured note of ICA-T (as such may be amended, restated, extended, replaced or otherwise modified from time to time
in accordance with the terms thereof, the “ICA-T Note”) and (ii) the Parent shall be required to sell a $2,000,000
aggregate principal amount aggregate principal amount senior secured note of the Parent (as such may be amended, restated, extended,
replaced or otherwise modified from time to time in accordance with the terms thereof, the “Parent Note” and
together with the ICA-T Note, collectively, the “Notes”) to the Buyer and the Buyer shall have the right to
purchase the Notes;

 

WHEREAS,
the Securities Purchase Agreement requires that the Guarantors execute and deliver to the Collateral Agent simultaneously with
the execution of the Securities Purchase Agreement (i) a guaranty guaranteeing all of the obligations of the Parent, ICA-T and
the Subsidiaries under the Securities Purchase Agreement, the Parent Note, the ICA-T Note and the other Transaction Documents
(as defined below); and (ii) a Security and Pledge Agreement, dated as of the date hereof, granting the Collateral Agent for the
benefit of the Noteholders a lien on and security interest in all of their assets and properties (the “Security Agreement”);
and

 

WHEREAS,
each Guarantor has determined that the execution, delivery and performance of this Guaranty directly benefits, and is in the best
interest of, such Guarantor and that the Buyer would not have entered into the Securities Purchase Agreement and the other Transaction
Documents and/or taken the actions required of it under such documents including purchasing the Notes if the Guarantor had executed
and delivered this Guaranty.

 

    	 		 

     

    

 

NOW,
THEREFORE, in consideration of the premises and the agreements herein and in order to induce the Buyer to perform under the Securities
Purchase Agreement, each Guarantor hereby agrees with the Buyer as follows:

 

SECTION
1. Definitions. Reference is hereby made to the Securities Purchase Agreement and the Notes for a statement of the terms
thereof. All terms used in this Guaranty and the recitals hereto which are defined in the Securities Purchase Agreement or the
Notes, and which are not otherwise defined herein shall have the same meanings herein as set forth therein. In addition, the following
terms when used in the Guaranty shall have the meanings set forth below:

 

“Bankruptcy
Code” means Chapter 11 of Title 11 of the United States Code, 11 U.S.C §§ 101 et seq. (or other applicable
bankruptcy, insolvency or similar laws).

 

“Business
Day” means any day other than Saturday, Sunday or other day on which commercial banks in New York City are authorized
or required by law to remain closed.

 

“Buyer”
shall have the meaning set forth in the recitals hereto.

 

“Capital
Stock” means (i) with respect to any Person that is a corporation, any and all shares, interests, participations or
other equivalents (however designated and whether or not voting) of corporate stock (including, without limitation, any warrants,
options, rights or other securities exercisable or convertible into equity interests or securities of such Person), and (ii) with
respect to any Person that is not a corporation, any and all partnership, membership or other equity interests of such Person.

 

“Collateral”
means all assets and properties of the Parent and each other Guarantor, wherever located and whether now or hereafter existing
and whether now owned or hereafter acquired, of every kind and description, tangible or intangible, including, without limitation,
the collateral described in Section 2 of the Security Agreement.

 

“Collateral
Agent” shall have the meaning set forth in the recitals hereto.

 

“Governmental
Authority” means any nation or government, any Federal, state, city, town, municipality, county, local, foreign or other
political subdivision thereof or thereto and any department, commission, board, bureau, instrumentality, agency or other entity
exercising executive, legislative, judicial, taxing, regulatory or administrative powers or functions of or pertaining to government.

 

“Guaranteed
Obligations” shall have the meaning set forth in Section 2 of this Guaranty.

 

“Guarantor”
or “Guarantors” shall have the meaning set forth in the first paragraph of this Guaranty.

 

“ICA-T
Note” shall have the meaning set forth in the recitals hereto.

 

“Indemnified
Party” shall have the meaning set forth in Section 13(a) of this Guaranty

 

“Insolvency
Proceeding” means any proceeding commenced by or against any Person under any provision of the Bankruptcy Code or under
any other bankruptcy or insolvency law, assignments for the benefit of creditors, formal or informal moratoria, compositions,
or extensions generally with creditors, or proceedings seeking reorganization, arrangement, or other similar relief.

 

    	 	2	 

     

    

 

“Noteholders”
means the Buyer and any other holder of all or any portion of the ICA-T Note.

 

“Obligations”
shall have the meaning set forth in Section 3 of the Security Agreement.

 

“Other
Taxes” shall have the meaning set forth in Section 12(a)(iv) of this Guaranty.

 

“Paid
in Full” or “Payment in Full” means the indefeasible payment in full in cash (and/or through the issuance
of Parent Common Stock (as defined in the Notes) but solely to the extent, in accordance with and pursuant to the terms of the
Notes) of all of the Guaranteed Obligations.

 

“Parent”
shall have the meaning set forth in the recitals hereto.

 

“Person”
means an individual, corporation, limited liability company, partnership, association, joint-stock company, trust, unincorporated
organization, joint venture or other enterprise or entity or Governmental Authority.

 

“Securities
Purchase Agreement” shall have the meaning set forth in the recitals hereto.

 

“Security
Agreement” shall have the meaning set forth in the recitals hereto.

 

“Subsidiary”
means any Person in which a Guarantor directly or indirectly (i) owns a majority of the outstanding Capital Stock, voting
stock or holds any equity or similar interest of such Person including, but not limited to, any Subsidiary of ICA-T or (ii) controls
or operates a substantial portion of the business, operations or administration of such Person including, but not limited to,
any Subsidiary of ICA-T, and all of the foregoing, collectively, “Subsidiaries”.

 

“Taxes”
shall have the meaning set forth in Section 12(a) of this Guaranty.

 

“Transaction
Party” means the Parent, ICA-T and each other Guarantor, collectively, “Transaction Parties”.

 

SECTION
2. Guaranty.

 

(a)       The
Guarantors, jointly and severally, hereby unconditionally and irrevocably, guaranty to the Collateral Agent, for the benefit of
the Collateral Agent, the Buyer and any other Noteholder the punctual payment, as and when due and payable, by stated maturity,
acceleration or otherwise, of all Obligations of including, without limitation, all interest, make-whole, redemption and other
amounts that accrue after the commencement of any Insolvency Proceeding of the Parent, ICA-T or any Guarantor, whether or not
the payment of such principal, interest, make-whole, redemption and/or other amounts are enforceable or are allowable in such
Insolvency Proceeding, and all fees, Late Charges (as defined in the Notes), interest, premiums, penalties, causes of actions,
costs, commissions, expense reimbursements, indemnifications and all other amounts due or to become due under the Notes and the
other Transaction Documents and (all of the foregoing collectively being the “Guaranteed Obligations”), and
agree to pay any and all costs and expenses (including reasonable and documented counsel fees and expenses) incurred by the Collateral
Agent in enforcing any rights under this Guaranty or any other Transaction Document. Without limiting the generality of the foregoing,
each Guarantor’s liability hereunder shall extend to all amounts that constitute part of the Guaranteed Obligations and
would be owed by the Parent, ICA-T or any Guarantor to the Collateral Agent or the Buyer under the Securities Purchase Agreement,
the Notes and any other Transaction Document but for the fact that they are unenforceable or not allowable due to the existence
of an Insolvency Proceeding involving any Transaction Party.

 

    	 	3	 

     

    

 

(b)       Each
Guarantor, and by its acceptance of this Guaranty, the Collateral Agent and the Buyer, hereby confirms that it is the intention
of all such Persons that this Guaranty and the Guaranteed Obligations of each Guarantor hereunder not constitute a fraudulent
transfer or conveyance for purposes of the Bankruptcy Code, the Uniform Fraudulent Conveyance Act, the Uniform Fraudulent Transfer
Act or any similar foreign, federal, provincial, state, or other applicable law to the extent applicable to this Guaranty and
the Guaranteed Obligations of each Guarantor hereunder. To effectuate the foregoing intention, the Collateral Agent, the Buyer
and the Guarantors hereby irrevocably agree that the Guaranteed Obligations of each Guarantor under this Guaranty at any time
shall be limited to the maximum amount as will result in the Guaranteed Obligations of such Guarantor under this Guaranty not
constituting a fraudulent transfer or conveyance.

 

SECTION
3. Guaranty Absolute; Continuing Guaranty; Assignments.

 

(a)       The
Guarantors, jointly and severally, guaranty that the Guaranteed Obligations will be paid strictly in accordance with the terms
of the Notes and the other Transaction Documents, regardless of any law, regulation or order now or hereafter in effect in any
jurisdiction affecting any of such terms or the rights of the Collateral Agent, the Buyer and/or any other Noteholder with respect
thereto. The obligations of each Guarantor under this Guaranty are independent of the Guaranteed Obligations, and a separate action
or actions may be brought and prosecuted against any Guarantor to enforce such obligations, irrespective of whether any action
is brought against any Transaction Party or whether any Transaction Party is joined in any such action or actions. The liability
of any Guarantor under this Guaranty shall be as a primary obligor (and not merely as a surety) and shall be irrevocable, absolute
and unconditional irrespective of, and each Guarantor hereby irrevocably waives, to the maximum extent permitted by law, any defenses
it may now or hereafter have in any way relating to, any or all of the following:

 

(i)         any
lack of validity or enforceability of the Notes and/or any other Transaction Document;

 

(ii)        any
change in the time, manner or place of payment of, or in any other term of, all or any of the Guaranteed Obligations, or any other
amendment or waiver of or any consent to departure from any Transaction Document, including, without limitation, any increase
in the Guaranteed Obligations resulting from the extension of additional credit to any Transaction Party or extension of the maturity
of any Guaranteed Obligations or otherwise;

 

(iii)       any
taking, exchange, release or non-perfection of any Collateral;

 

    	 	4	 

     

    

 

(iv)       any
taking, release or amendment or waiver of or consent to departure from any other guaranty, for all or any of the Guaranteed Obligations;

 

(v)        any
change, restructuring or termination of the corporate, limited liability company or partnership structure or existence of any
Transaction Party;

 

(vi)       any
manner of application of Collateral or any other collateral, or proceeds thereof, to all or any of the Guaranteed Obligations,
or any manner of sale or other disposition of any Collateral or any other collateral for all or any of the Guaranteed Obligations
or any other Obligations of any Transaction Party under the Transaction Documents or any other assets of any Transaction Party
or any of its Subsidiaries;

 

(vii)      any
failure of the Collateral Agent, the Buyer and/or any other Noteholder to disclose to any Transaction Party any information relating
to the business, condition (financial or otherwise), operations, performance, properties or prospects of any other Transaction
Party now or hereafter known to the Collateral Agent, the Buyer and/or any other Noteholder (each Guarantor waiving any duty on
the part of the Collateral Agent, the Buyer and/or any other Noteholder to disclose such information);

 

(viii)     taking
any action in furtherance of the release of any Guarantor or any other Person that is liable for the Obligations from all or any
part of any liability arising under or in connection with any Transaction Document without the prior written consent of the Collateral
Agent; or

 

(ix)        any
other circumstance (including, without limitation, any statute of limitations) or any existence of or reliance on any representation
by the Collateral Agent, the Buyer and/or any other Noteholder that might otherwise constitute a defense available to, or a discharge
of, any Transaction Party or any other guarantor or surety.

 

(b)       This
Guaranty shall continue to be effective or be reinstated, as the case may be, if at any time any payment of any of the Guaranteed
Obligations is rescinded or must otherwise be returned by the Collateral Agent, the Buyer, any other Noteholder and/or any other
Person upon the insolvency, bankruptcy or reorganization of any Transaction Party or otherwise, all as though such payment had
not been made.

 

(c)       This
Guaranty is a continuing guaranty and shall (i) remain in full force and effect until Payment in Full of the Guaranteed Obligations
(other than inchoate indemnity obligations) and shall not terminate for any reason prior to the Maturity Date of the Notes (other
than Payment in Full of the Guaranteed Obligations), and (ii) be binding upon each Guarantor and its respective successors and
assigns. This Guaranty shall inure to the benefit of and be enforceable by the Collateral Agent, the Buyer and/or any other Noteholder
and their respective successors, and permitted pledgees, transferees and assigns. Without limiting the generality of the foregoing
sentence, the Collateral Agent, the Buyer and/or any other Noteholder may pledge, assign or otherwise transfer all or any portion
of its rights, remedies and obligations under and subject to the terms of any Transaction Document to any other Person [other
than to the Buyer Affiliate] [(as defined in the Securities Purchase Agreement)] and such other Person shall thereupon become
vested with all the benefits in respect thereof granted to the Collateral Agent, the Buyer and/or any other Noteholder (as applicable)
herein or otherwise, in each case as provided in the Securities Purchase Agreement or such other Transaction Document.

 

    	 	5	 

     

    

 

SECTION
4. Waivers. To the extent permitted by applicable law, each Guarantor hereby waives promptness, diligence, protest, notice
of acceptance and any other notice or formality of any kind with respect to any of the Guaranteed Obligations and this Guaranty
and any requirement that the Collateral Agent exhaust any right or take any action against any Transaction Party or any other
Person or any Collateral. Each Guarantor acknowledges that it will receive direct and indirect benefits from the financing arrangements
contemplated herein and that the waiver set forth in this Section 4 is knowingly made in contemplation of such benefits.
The Guarantors hereby waive any right to revoke this Guaranty, and acknowledge that this Guaranty is continuing in nature and
applies to all Guaranteed Obligations, whether existing now or in the future. Without limiting the foregoing, to the extent permitted
by applicable law, each Guarantor hereby unconditionally and irrevocably waives (a) any defense arising by reason of any claim
or defense based upon an election of remedies by the Collateral Agent or the Buyer that in any manner impairs, reduces, releases
or otherwise adversely affects the subrogation, reimbursement, exoneration, contribution or indemnification rights of such Guarantor
or other rights of such Guarantor to proceed against any of the other Transaction Parties, any other guarantor or any other Person
or any Collateral, and (b) any defense based on any right of set-off or counterclaim against or in respect of the Guaranteed Obligations
of such Guarantor hereunder. Each Guarantor hereby unconditionally and irrevocably waives any duty on the part of the Collateral
Agent, the Buyer and/or any other Noteholder to disclose to such Guarantor any matter, fact or thing relating to the business,
condition (financial or otherwise), operations, performance, properties or prospects of any other Transaction Party or any of
its Subsidiaries now or hereafter known by the Collateral Agent, the Buyer and/or any other Noteholder.

 

SECTION
5. Subrogation. No Guarantor may exercise any rights that it may now or hereafter acquire against any Transaction Party
or any other Guarantor and/or guarantor that arise from the existence, payment, performance or enforcement of any Guarantor’s
obligations under this Guaranty, including, without limitation, any right of subrogation, reimbursement, exoneration, contribution
or indemnification and any right to participate in any claim or remedy of the Collateral Agent, the Buyer and/or any other Noteholder
against any Transaction Party or any other guarantor or any Collateral, whether or not such claim, remedy or right arises in equity
or under contract, statute or common law, including, without limitation, the right to take or receive from any Transaction Party
or any other guarantor, directly or indirectly, in cash or other property or by set-off or in any other manner, payment or security
solely on account of such claim, remedy or right, unless and until there has been Payment in Full of the Guaranteed Obligations.
If any amount shall be paid to a Guarantor in violation of the immediately preceding sentence at any time prior to Payment in
Full of the Guaranteed Obligations and all other amounts payable under this Guaranty, such amount shall be held in trust for the
benefit of the Collateral Agent and shall forthwith be paid to the Collateral Agent to be credited and applied to the Guaranteed
Obligations and all other amounts payable under this Guaranty, whether matured or un-matured, in accordance with the terms of
the Transaction Document, or to be held as Collateral for any Guaranteed Obligations or other amounts payable under this Guaranty
thereafter arising. If (a) any Guarantor shall make payment to the Collateral Agent of all or any part of the Guaranteed Obligations,
and (b) there has been Payment in Full of the Guaranteed Obligations, the Collateral Agent will, at such Guarantor’s request
and expense, execute and deliver to such Guarantor appropriate documents to evidence payment in Full of the Guaranteed Obligations
without recourse and without representation or warranty, necessary to evidence the transfer by subrogation to such Guarantor of
an interest in the Guaranteed Obligations resulting from such payment by such Guarantor.

 

    	 	6	 

     

    

 

SECTION
6. Representations, Warranties and Covenants.

 

(a)       Each
Guarantor hereby represents and warrants as of the date first written above as follows:

 

(i)         such
Guarantor (A) is a corporation, limited liability company or limited partnership duly organized, validly existing and in good
standing under the laws of the jurisdiction of its organization as set forth on the signature pages hereto, (B) has all requisite
corporate, limited liability company or limited partnership power and authority to conduct its business as now conducted and as
presently contemplated and to execute, deliver and perform its obligations under this Guaranty and each other Transaction Document
to which such Guarantor is a party, and to consummate the transactions contemplated hereby and thereby and (C) is duly qualified
to do business and is in good standing in each jurisdiction in which the character of the properties owned or leased by it or
in which the transaction of its business makes such qualification necessary except where the failure to be so qualified (individually
or in the aggregate) would not result in a Material Adverse Effect.

 

(ii)        The
execution, delivery and performance by such Guarantor of this Guaranty and each other Transaction Document to which such Guarantor
is a party (A) have been duly authorized by all necessary corporate, limited liability company or limited partnership action,
(B) do not and will not contravene its charter, articles, certificate of formation or by-laws, its limited liability company or
operating agreement or its certificate of partnership or partnership agreement, as applicable, or any applicable law or any contractual
restriction binding on such Guarantor or its properties do not and will not result in or require the creation of any lien, security
interest or encumbrance (other than pursuant to any Transaction Document) upon or with respect to any of its properties, and (C)
do not and will not result in any default, noncompliance, suspension, revocation, impairment, forfeiture or nonrenewal of any
material permit, license, authorization or approval applicable to it or its operations or any of its properties.

 

(iii)       No
authorization or approval or other action by, and no notice to or filing with, any Governmental Authority or other Person is required
in connection with the due execution, delivery and performance by such Guarantor of this Guaranty or any of the other Transaction
Documents to which such Guarantor is a party (other than expressly provided for in any of the Transaction Documents).

 

    	 	7	 

     

    

 

(iv)       This
Guaranty has been duly executed and delivered by each Guarantor and is, and each of the other Transaction Documents to which such
Guarantor is or will be a party, when executed and delivered, will be, a legal, valid and binding obligation of such Guarantor,
enforceable against such Guarantor in accordance with its terms, except as may be limited by the Bankruptcy Code or other applicable
bankruptcy, insolvency, reorganization, moratorium, fraudulent conveyance, suretyship or similar laws and equitable principles
(regardless of whether enforcement is sought in equity or at law).

 

(v)       There
is no pending or, to the knowledge of such Guarantor, threatened action, suit or proceeding against such Guarantor or to which
any of the properties of such Guarantor is subject, before any court or other Governmental Authority or any arbitrator that (A)
if adversely determined, could reasonably be expected to have a Material Adverse Effect or (B) relates to this Guaranty or any
of the other Transaction Documents to which such Guarantor is a party or any transaction contemplated hereby or thereby.

 

(vi)       Such
Guarantor (A) has read and understands the terms and conditions of the Securities Purchase Agreement and the other Transaction
Documents, and (B) now has and will continue to have independent means of obtaining information concerning the affairs, financial
condition and business of the Parent and the other Transaction Parties, and has no need of, or right to obtain from the Collateral
Agent or the Buyer, any credit or other information concerning the affairs, financial condition or business of the Parent or the
other Transaction Parties.

 

(vii)      There
are no conditions precedent to the effectiveness of this Guaranty that have not been satisfied or waived.

 

(b)       Each
Guarantor covenants and agrees that until Payment in Full of the Guaranteed Obligations, it will comply with each of the covenants
which are set forth in Section 4 of the Securities Purchase Agreement as if such Guarantor were a party thereto.

 

SECTION
7. Right of Set-off. Upon the occurrence and during the continuance of any Event of Default, the Collateral Agent, the
Buyer and/or any other Noteholder may, and is hereby authorized to, at any time and from time to time, without notice to the Guarantors
(any such notice being expressly waived by each Guarantor) and to the fullest extent permitted by law, set-off and apply any and
all deposits (general or special, time or demand, provisional or final) at any time held and other indebtedness at any time owing
by the Collateral Agent, the Buyer and/or any other Noteholder to or for the credit or the account of any Guarantor against any
and all obligations of the Guarantors now or hereafter existing under this Guaranty or any other Transaction Document, irrespective
of whether or not the Collateral Agent, the Buyer and/or any other Noteholder shall have made any demand under this Guaranty or
any other Transaction Document and although such obligations may be contingent or unmatured. The Collateral Agent, the Buyer and/or
any other Noteholder agrees to notify the relevant Guarantor promptly after any such set-off and application made by the Collateral
Agent or the Buyer, provided that the failure to give such notice shall not affect the validity of such set-off and application.
The rights of the Collateral Agent, the Buyer and/or any other Noteholder under this Section 7 are in addition to other
rights and remedies (including, without limitation, other rights of set-off) which the Collateral Agent, the Buyer and/or any
other Noteholder may have under this Guaranty or any other Transaction Document in law or otherwise.

 

    	 	8	 

     

    

 

SECTION
8. Limitation on Guaranteed Obligations.

 

(a)       Notwithstanding
any provision herein contained to the contrary, each Guarantor’s liability hereunder shall be limited to an amount not to
exceed as of any date of determination the greater of:

 

(i)         the
amount of all Guaranteed Obligations, plus interest thereon at the applicable Interest Rate as specified in the Notes; and

 

(ii)        the
amount which could be claimed by the Collateral Agent from any Guarantor under this Guaranty without rendering such claim voidable
or avoidable under the Bankruptcy Code or under any applicable state Uniform Fraudulent Transfer Act, Uniform Fraudulent Conveyance
Act or similar statute or common law after taking into account, among other things, Guarantor’s right of contribution and
indemnification.

 

(b)       Each
Guarantor agrees that the Guaranteed Obligations may at any time and from time to time exceed the amount of the liability of such
Guarantor hereunder without impairing the guaranty hereunder or affecting the rights and remedies of the Collateral Agent, the
Buyer and/or any other Noteholder hereunder or under applicable law.

 

(c)       No
payment made by ICA-T, any Guarantor, any other guarantor or any other Person or received or collected by the Collateral Agent,
the Buyer and/or any other Noteholder from ICA-T, any of the Guarantors, any other guarantor or any other Person by virtue of
any action or proceeding or any set-off or appropriation or application at any time or from time to time in reduction of or in
payment of the Guaranteed Obligations shall be deemed to modify, reduce, release or otherwise affect the liability of any Guarantor
hereunder which shall, notwithstanding any such payment (other than any payment made by such Guarantor in respect of the Guaranteed
Obligations or any payment received or collected from such Guarantor in respect of the Guaranteed Obligations), remain liable
for the Guaranteed Obligations up to the maximum liability of such Guarantor hereunder until after all of the Guaranteed Obligations
and all other amounts payable under this Guaranty shall have been Paid in Full.

 

SECTION
9. Notices, Etc. Any notices, consents, waivers or other communications required or permitted to be given under the terms
of this Guaranty must be in writing and will be deemed to have been delivered: (i) upon receipt, when delivered personally; (ii)
upon receipt, when sent by facsimile or email (provided confirmation of transmission is mechanically or electronically generated
or, in the case of email with a read receipt generated and kept on file by the sending party); or (iii) one (1) Business Day after
deposit with a nationally recognized overnight courier service with next day delivery specified, in each case, properly addressed
to the party to receive the same. All notices and other communications provided for hereunder shall be sent, if to any Guarantor,
to the Parent’s address and/or facsimile number, or if to the Collateral Agent, the Buyer and/or any other Noteholder, to
it at its respective address and/or facsimile number, each as set forth in Section 9(f) of the Securities Purchase Agreement.

 

    	 	9	 

     

    

 

SECTION
10. Governing Law; Jurisdiction. All questions concerning the construction, validity, enforcement and interpretation of
this Guaranty shall be governed by the internal laws of the State of New York, without giving effect to any choice of law or conflict
of law provision or rule (whether of the State of New York or any other jurisdictions) that would cause the application of the
laws of any jurisdictions other than the State of New York. Each Guarantor hereby irrevocably submits to the exclusive jurisdiction
of the state and federal courts sitting in The City of New York, Borough of Manhattan, for the adjudication of any dispute hereunder
or in connection herewith or under any of the other Transaction Documents or with any transaction contemplated hereby or thereby,
and hereby irrevocably waives, and agrees not to assert in any suit, action or proceeding, any claim, obligation or defense that
it is not personally subject to the jurisdiction of any such court, that such suit, action or proceeding is brought in an inconvenient
forum or that the venue of such suit, action or proceeding is improper. Each party hereby irrevocably waives personal service
of process and consents to process being served in any such suit, action or proceeding by mailing a copy thereof to such party
at the address for such notices to it under Section 9(f) of the Securities Purchase Agreement and agrees that such service shall
constitute good and sufficient service of process and notice thereof. Nothing contained herein shall be deemed to limit in any
way any right to serve process in any manner permitted by law. Nothing contained herein shall be deemed or operate to preclude
the Collateral Agent or the Buyer from bringing suit or taking other legal action against any Guarantor in any other jurisdiction
to collect on a Guarantor’s obligations or to enforce a judgment or other court ruling in favor of the Collateral Agent
or the Buyer. 

 

SECTION
11. WAIVER OF JURY TRIAL, ETC. EACH GUARANTOR HEREBY IRREVOCABLY WAIVES ANY RIGHT IT MAY HAVE TO, AND AGREES NOT TO REQUEST,
A JURY TRIAL FOR THE ADJUDICATION OF ANY DISPUTE HEREUNDER OR UNDER ANY OTHER TRANSACTION DOCUMENT OR IN CONNECTION WITH OR ARISING
OUT OF THIS GUARANTY, ANY OTHER TRANSACTION DOCUMENT OR ANY TRANSACTION CONTEMPLATED HEREBY OR THEREBY.

 

SECTION
12. Taxes.

 

(a)       All
payments made by any Guarantor hereunder or under any other Transaction Document shall be made in accordance with the terms of
the respective Transaction Document and shall be made without set-off, counterclaim, withholding, deduction or other defense.
Without limiting the foregoing, all such payments shall be made free and clear of and without deduction or withholding for any
present or future taxes, levies, imposts, deductions, charges or withholdings, and all liabilities with respect thereto, excluding
taxes imposed on the net income of the Collateral Agent, the Buyer and/or any other Noteholder by the jurisdiction in which
the Collateral Agent, the Buyer and/or any other Noteholder is organized or where it has its principal lending office (all such
non-excluded taxes, levies, imposts, deductions, charges, withholdings and liabilities, collectively or individually, “Taxes”).
If any Guarantor shall be required to deduct or to withhold any Taxes from or in respect of any amount payable hereunder or under
any other Transaction Document:

 

(i)         the
amount so payable shall be increased to the extent necessary so that after making all required deductions and withholdings (including
Taxes on amounts payable to the Collateral Agent or the Buyer pursuant to this sentence) the Collateral Agent or the Buyer receives
an amount equal to the sum it would have received had no such deduction or withholding been made,

 

    	 	10	 

     

    

 

(ii)        such
Guarantor shall make such deduction or withholding,

 

(iii)       such
Guarantor shall pay the full amount deducted or withheld to the relevant Governmental Authority in accordance with applicable
law, and

 

(iv)       as
promptly as possible thereafter, such Guarantor shall send the Collateral Agent or the Buyer an official receipt (or, if an official
receipt is not available, such other documentation as shall be satisfactory to the Collateral Agent, as the case may be) showing
payment. In addition, each Guarantor agrees to pay any present or future stamp or documentary taxes or any other excise or property
taxes, charges or similar levies that arise from any payment made hereunder or from the execution, delivery, registration or enforcement
of, or otherwise with respect to, this Guaranty or any other Transaction Document (collectively, “Other Taxes”).

 

(b)       Each
Guarantor hereby indemnifies and agrees to hold each Indemnified Party harmless from and against Taxes or Other Taxes (including,
without limitation, any Taxes or Other Taxes imposed by any jurisdiction on amounts payable under this Section 12) paid
by any Indemnified Party as a result of any payment made hereunder or from the execution, delivery, registration or enforcement
of, or otherwise with respect to, this Guaranty or any other Transaction Document, and any liability (including penalties, interest
and expenses for nonpayment, late payment or otherwise) arising therefrom or with respect thereto, whether or not such Taxes or
Other Taxes were correctly or legally asserted so long as each Guarantor was provided with the right set forth above. This indemnification
shall be paid within thirty (30) days from the date on which the Collateral Agent or the Buyer makes written demand therefor,
which demand shall identify the nature and amount of such Taxes or Other Taxes.

 

(c)       If
any Guarantor fails to perform any of its obligations under this Section 12, such Guarantor shall indemnify the Collateral
Agent and the Buyer for any taxes, interest or penalties that may become payable as a result of any such failure. The obligations
of the Guarantors under this Section 12 shall survive the termination of this Guaranty and the payment of the Obligations
and all other amounts payable hereunder.

 

SECTION
13. Indemnification.

 

(a)       Without
limitation of any other obligations of any Guarantor or remedies of the Collateral Agent or the Buyer under this Guaranty or applicable
law, except to the extent resulting from such Indemnified Party’s gross negligence or willful misconduct, as determined
by a final judgment of a court of competent jurisdiction no longer subject to appeal, each Guarantor shall, to the fullest extent
permitted by law, indemnify, defend and save and hold harmless the Collateral Agent and the Buyer and each of their affiliates
and their respective officers, directors, members, managers, employees, agents and advisors (each, an “Indemnified Party”)
from and against, and shall pay on demand, any and all claims, damages, losses, liabilities and expenses (including, without limitation,
reasonable fees and expenses of counsel) that may be incurred by or asserted or awarded against any Indemnified Party in connection
with or as a result of any failure of any Guaranteed Obligations to be the legal, valid and binding obligations of any Transaction
Party enforceable against such Transaction Party in accordance with their terms.

 

    	 	11	 

     

    

 

(b)       Each
Guarantor hereby also agrees that none of the Indemnified Parties shall have any liability (whether direct or indirect, in contract,
tort or otherwise) or any fiduciary duty or obligation to any of the Guarantors or any of their respective affiliates or any of
their respective officers, directors, employees, agents and advisors, and each Guarantor hereby agrees not to assert any claim
against any Indemnified Party on any theory of liability, for special, indirect, consequential, incidental or punitive damages
arising out of or otherwise relating to the facilities, the actual or proposed use of the proceeds of the advances, the Transaction
Documents or any of the transactions contemplated by the Transaction Documents.

 

SECTION
14. Miscellaneous.

 

(a)       Each
Guarantor will make each payment hereunder in lawful money of the United States of America and in immediately available funds
to the Collateral Agent or the Buyer, at such address specified by the Collateral Agent or the Buyer from time to time by notice
to the Guarantors.

 

(b)       No
amendment or waiver of any provision of this Guaranty and no consent to any departure by any Guarantor therefrom shall in any
event be effective unless the same shall be in writing and signed by each Guarantor, the Collateral Agent and the Buyer, and then
such waiver or consent shall be effective only in the specific instance and for the specific purpose for which given.

 

(c)       No
failure on the part of the Collateral Agent or the Buyer to exercise, and no delay in exercising, any right or remedy hereunder
or under any other Transaction Document shall operate as a waiver thereof, nor shall any single or partial exercise of any right
hereunder or under any Transaction Document preclude any other or further exercise thereof or the exercise of any other right
or remedy. The rights and remedies of the Collateral Agent and the Buyer provided herein and in the other Transaction Documents
are cumulative and are in addition to, and not exclusive of, any rights or remedies provided by law. The rights and remedies of
the Collateral Agent and the Buyer under any Transaction Document against any party thereto are not conditional or contingent
on any attempt by the Collateral Agent or the Buyer to exercise any of their respective rights or remedies under any other Transaction
Document against such party or against any other Person.

 

(d)       If
any provision of this Guaranty or any Transaction Document is prohibited by law or otherwise determined to be invalid or unenforceable
by a court of competent jurisdiction, the provision that would otherwise be prohibited, invalid or unenforceable shall be deemed
amended to apply to the broadest extent that it would be valid and enforceable, and the invalidity or unenforceability of such
provision shall not affect the validity of the remaining provisions of this Guaranty so long as this Guaranty as so modified continues
to express, without material change, the original intentions of the parties as to the subject matter hereof and the prohibited
nature, invalidity or unenforceability of the provision(s) in question does not substantially impair the respective expectations
or reciprocal obligations of the parties or the practical realization of the benefits that would otherwise be conferred upon the
parties.  The parties will endeavor in good faith negotiations to replace the prohibited, invalid or unenforceable provision(s)
with a valid provision(s), the effect of which comes as close as possible to that of the prohibited, invalid or unenforceable
provision(s).

 

    	 	12	 

     

    

 

(e)       This
Guaranty is a continuing guaranty and shall (i) remain in full force and effect until Payment in Full of the Guaranteed Obligations
(other than inchoate indemnity obligations) and shall not terminate for any reason prior to the respective Maturity Date of the
Notes (other than Payment in Full of the Guaranteed Obligations) and (ii) be binding upon each Guarantor and its respective successors
and assigns. This Guaranty shall inure, together with all rights and remedies of the Collateral Agent hereunder, to the benefit
of and be enforceable by the Collateral Agent, the Buyer, and their respective successors, and permitted pledgees, transferees
and assigns. Without limiting the generality of the foregoing sentence, the Collateral Agent or the Buyer may pledge, assign or
otherwise transfer all or any portion of its rights and obligations under and subject to the terms of the Securities Purchase
Agreement or any other Transaction Document to any other Person in accordance with the terms thereof, and such other Person shall
thereupon become vested with all the benefits in respect thereof granted to the Collateral Agent or the Buyer (as applicable)
herein or otherwise, in each case as provided in the Securities Purchase Agreement or such Transaction Document. None of the rights
or obligations of any Guarantor hereunder may be assigned or otherwise transferred without the prior written consent of the Buyer.

 

(f)       This
Guaranty and the other Transaction Documents reflect the entire understanding of the transaction contemplated hereby and shall
not be contradicted or qualified by any other agreement, oral or written, entered into before the date hereof.

 

(g)       The
headings of this Guaranty are for convenience of reference and shall not form part of, or affect the interpretation of, this Guaranty.
 Unless the context clearly indicates otherwise, each pronoun herein shall be deemed to include the masculine, feminine,
neuter, singular and plural forms thereof.  The terms “including,” “includes,” “include”
and words of like import shall be construed broadly as if followed by the words “without limitation.”  The terms
“herein,” “hereunder,” “hereof” and words of like import refer to this entire Agreement instead
of just the provision in which they are found.

 

SECTION
15. Currency Indemnity.

 

If,
for the purpose of obtaining or enforcing judgment against Guarantor in any court in any jurisdiction, it becomes necessary to
convert into any other currency (such other currency being hereinafter in this Section 15 referred to as the “Judgment
Currency”) an amount due under this Guaranty in any currency (the “Obligation Currency”) other than
the Judgment Currency, the conversion shall be made at the rate of exchange prevailing on the Business Day immediately preceding
(a) the date of actual payment of the amount due, in the case of any proceeding in the courts of courts of the jurisdiction that
will give effect to such conversion being made on such date, or (b) the date on which the judgment is given, in the case of any
proceeding in the courts of any other jurisdiction (the applicable date as of which such conversion is made pursuant to this Section
15 being hereinafter in this Section 15 referred to as the “Judgment Conversion Date”).

 

If,
in the case of any proceeding in the court of any jurisdiction referred to in the preceding paragraph, there is a change in the
rate of exchange prevailing between the Judgment Conversion Date and the date of actual receipt of the amount due in immediately
available funds, the Guarantors shall pay such additional amount (if any, but in any event not a lesser amount) as may be necessary
to ensure that the amount actually received in the Judgment Currency, when converted at the rate of exchange prevailing on the
date of payment, will produce the amount of the Obligation Currency which could have been purchased with the amount of’
the Judgment Currency stipulated in the judgment or judicial order at the rate of exchange prevailing on the Judgment Conversion
Date. Any amount due from the Guarantors under this Section 15 shall be due as a separate debt and shall not be affected
by judgment being obtained for any other amounts due under or in respect of this Guaranty.

 

[REMAINDER
OF THIS PAGE INTENTIONALLY LEFT BLANK]

 

    	 	13	 

     

    

 

IN
WITNESS WHEREOF, each Guarantor has caused this Guaranty to be executed by its respective duly authorized officer, as of the date
first above written.

	 	 	 
	 	GUARANTORS:
	 	 	 
	 	ICAGEN,
    INC.,
	 	a
    Delaware corporation
	 	 	 
	 	By:	/s/
Richard Cunningham
	 	 	Name:
    Richard Cunningham
	 	 	Title:
    Chief Executive Officer
	 	 	 
	 	ICAGEN
    CORP (FORMERLY KNOWN AS XRPRO CORP.)., a Nevada corporation
	 	 	 
	 	By:	/s/
    Richard Cunningham
	 	 	Name:
    Richard Cunningham
	 	 	Title:
    Chief Executive Officer
	 	 	 
	 	CALDERA
    DISCOVERY, INC.,
	 	a
    Delaware corporation
	 	 	 
	 	By:	/s/
    Richard Cunningham
	 	 	Name:
    Richard Cunningham
	 	 	Title:
    Chief Executive Officer
	 	 	 
	 	XRPRO
    SCIENCES, INC.,
	 	a
    Delaware corporation
	 	 	 
	 	By:	/s/
Richard Cunningham
	 	 	Name:
    Richard Cunningham
	 	 	Title:
    Chief Executive Officer

	 	 	 
	ACCEPTED
    BY:	 
	 	 	 
	GPB
    DEBT HOLDINGS II, LLC,	 
	as
    Collateral Agent	 
	 	 	 
	By:	/s/
David Gentile 	 
	 	Name:
    David     Gentile 	 
	 	Title:
    Manager	 

 

 

14

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