Document:

Exhibit 4.17

 

	RIGHTS CERTIFICATE #: 	NUMBER OF RIGHTS: 

 

THIS CERTIFICATE AND THE RIGHTS AND
OBLIGATIONS EVIDENCED HEREBY ARE SUBJECT TO THE TERMS AND CONDITIONS SET FORTH IN CRYOPORT, INC.’S PROSPECTUS, DATED [•],
2016 (THE “PROSPECTUS”). COPIES OF THE PROSPECTUS ARE AVAILABLE UPON REQUEST FROM GEORGESON INC., THE INFORMATION AGENT
FOR THE RIGHTS OFFERING. THE INFORMATION AGENT’S TELEPHONE NUMBER IS (800) 903-2897 (TOLL FREE).

 

CRYOPORT, INC.

Incorporated under the laws of the State
of Nevada

 

NON-TRANSFERABLE SUBSCRIPTION RIGHTS
CERTIFICATE

 

Evidencing Non-Transferable Subscription
Rights to Purchase Shares of

Common Stock, $0.001 par value per share, of Cryoport, Inc.

 

Subscription Price: $[•] per Full Share

 

THE SUBSCRIPTION RIGHTS WILL EXPIRE IF NOT
EXERCISED ON OR BEFORE

5:00 P.M., NEW YORK CITY TIME, ON [•], 2016, UNLESS EXTENDED BY THE COMPANY

 

REGISTERED OWNER:

 

THIS CERTIFIES THAT the registered owner
whose name is inscribed hereon is the owner of the number of non-transferable subscription rights (“Rights”)
set forth above. Each whole Right entitles the holder thereof to subscribe for and purchase [•] shares of common stock, par
value $0.001 per share (the “Common Stock”), of Cryoport, Inc., a Nevada corporation (the “Company”),
at a subscription price of $[•] per full share (the “Basic Subscription Privilege”), pursuant to the Company’s
rights offering, on the terms and subject to the conditions set forth in the Prospectus (including the proration provisions described
therein) and the “Instructions for Use of Subscription Rights Certificates” accompanying this certificate. If any shares
of Common Stock available for purchase in the rights offering are not purchased by other holders of Rights pursuant to the exercise
of their Basic Subscription Privilege (the “Excess Shares”), any Rights holder that exercises its Basic Subscription
Privilege in full may subscribe for a number of Excess Shares pursuant to the terms and conditions of the rights offering, subject
to availability and proration as described in the Prospectus (the “Over-Subscription Privilege”). The Rights
represented by this certificate may be exercised by completing Form 1 and any other appropriate forms on the reverse side hereof
and by returning the full payment of the subscription price for each share of Common Stock to be purchased in accordance with the
“Instructions for Use of Subscription Rights Certificates” that accompany this certificate.

 

This certificate is not valid unless countersigned
by the subscription agent and registered by the registrar. Witness the seal of Cryoport, Inc. and the signatures of its duly authorized
officers.

 

 Dated: [•], 2016

 

 

	 	 
	
        Chief Executive Officer
	
        Secretary and Chief Financial
        Officer

         

Countersigned: CONTINENTAL STOCK TRANSFER & TRUST COMPANY,
SUBSCRIPTION AGENT

 

 

 

By: ___________________________________

Authorized Officer

 

     

     

    

 

DELIVERY OPTIONS
FOR SUBSCRIPTION RIGHTS CERTIFICATE

 

Delivery other than in the manner or to
the addresses listed below will not constitute valid delivery. If delivering by mail, hand or overnight courier:

Continental Stock Transfer & Trust Company

Attn: Corporate Actions Department

17 Battery Place

New York, New York 10004

PLEASE PRINT ALL INFORMATION CLEARLY AND
LEGIBLY

FORM 1 - EXERCISE OF SUBSCRIPTION RIGHTS

 

To subscribe for shares pursuant to your Basic Subscription
Privilege, please complete lines (a), (c) and (d) and sign under Form 3 below. To subscribe for shares pursuant to your Over-Subscription
Privilege, please also complete line (b) and sign under Form 3 below. To the extent you subscribe for more shares than you are
entitled under either the Basic Subscription Privilege or the Over-Subscription Privilege, you will be deemed to have elected
to purchase the maximum number of shares for which you are entitled to subscribe under the Basic Subscription Privilege or Over-Subscription
Privilege, as applicable.

 

(a) EXERCISE OF BASIC SUBSCRIPTION PRIVILEGE:

 

	I am applying for  ________________________________	Shares X	 $ _________________________	= $ ________________________
	(number of new shares)	 	(subscription price)	(amount enclosed)

 

(b) EXERCISE OF OVER-SUBSCRIPTION PRIVILEGE:

 

If you have exercised your Basic Subscription Privilege in full
and wish to subscribe for additional shares of Common Stock pursuant to your Over-Subscription Privilege.

 

	I am applying for  ________________________________	Shares X	 $ _________________________	= $ ________________________
	(number of new shares)	 	(subscription price)	(amount enclosed)

 

(c) Total Amount of Payment Enclosed = $ ___________________

 

(d) METHOD OF PAYMENT (CHECK ONE)

 

 ̈          Check
or bank draft payable to “[•]”

 

 ̈          Wire
transfer of immediately available funds directly to the account maintained by Continental Stock Transfer & Trust Company,
as Subscription Agent, for purposes of accepting subscriptions in the rights offering, at [•].

 

FORM 2 - DELIVERY TO DIFFERENT ADDRESS

 

If you wish for the Common Stock underlying your Rights or a
certificate representing the remaining balance of unexercised Rights to be delivered to an address different from that shown on
the face of this certificate, enter the alternate address below, sign under Form 3 and have your signature guaranteed under Form
4.

 

______________________________________________________

______________________________________________________

______________________________________________________

 

FORM 3 - SIGNATURE

 

TO SUBSCRIBE: I acknowledge that I have received the Prospectus
for the rights offering and I hereby irrevocably subscribe for the number of shares indicated under Form 1 above on the terms and
conditions specified in the Prospectus. This Form 3 must be signed by the registered holder(s) exactly as their name(s) appear(s)
on the certificate(s) or by person(s) authorized to sign on behalf of the registered holder(s) by documents transmitted herewith.

 

Signature(s): ______________________________________________________

 

Signature(s): ______________________________________________________

 

Date: ______________________________________________________

 

Telephone Number: ______________________________________________________

 

IMPORTANT: The signature(s) must correspond with the name(s)
as printed on the reverse of this certificate in every particular, without alteration or enlargement, or any other change whatsoever.

 

FORM 4 – SIGNATURE GUARANTEE

 

This form must be completed if you have completed any portion
of Form 2.

 

Signature Guaranteed: ______________________________________________________
(Name of Bank or Firm)

 

By: ______________________________________________________ (Signature
of Officer)

 

IMPORTANT: The signature(s) should be guaranteed by an eligible
guarantor institution (bank, stock broker, savings & loan association or credit union) with membership in an approved signature
guarantee medallion program pursuant to Securities and Exchange Commission Rule 17Ad-15.

 

FOR INSTRUCTIONS ON THE USE OF THIS CERTIFICATE, CONTACT GEORGESON
INC., THE INFORMATION AGENT FOR THE RIGHTS OFFERING, AT (800) 903-2897 (TOLL FREE).Exhibit 10.1

 

	
         

         

        RBL Capital Group, LLC

        132
West 31st Street 

        14th
Floor 

        New york, ny
        10001

         

         

         

 

April 28, 2016

 

TOT Group, Inc., et al

3363 NE 163rd Street

Suite 705

North Miami Beach, FL 33160

 

Re:Loan and Security Agreement dated as of June 30, 2014,
as amended (the “Agreement”). All capitalized terms used herein shall have the definitions as given in the Agreement.

 

Mr. Oleg Firer,

 

On behalf of the Co-Borrowers, as such term is defined in the
referenced Agreement, you have requested a 90-day extension of the interest only period on the Revised Term Loan Note #1, dated
July 31, 2014, (b) Revised Term Loan Note #2, dated February 10, 2015, and (c) Revised Term Loan Note #3, dated March 27, 2015,
(collectively, the “Notes”). In consideration for and as a condition precedent to granting this forbearance,
RBL requires, that the ultimate parent of Co-Borrowers, Net Element, Inc., provide RBL Capital Group, LLC (“RBL”) with
a guarantee pertaining to the Notes as set forth below.

 

Net Element’s signature to this letter agreement shall
be a condition precedent to these extensions.

 

By your signature below, on behalf of all the Co-Borrowers,
you agree that RBL shall be entitled to collect a fee of ten thousand and 00/100 dollars ($10,000.00) for providing the requested
extensions. This fee will be collected per the terms of Section 3.02(a) of the Agreement.

 

All other terms and conditions of the Agreement shall remain
in full force and effect.

 

Accordingly, effective as of the date hereof, Net Element, Inc.
(NETE) and RBL agree as follows:

 

WHEREAS, RBL has entered
into that certain Loan and Security Agreement (the Agreement”) dated as of June 30, 2014, as amended, with TOT Group, Inc.;
TOT Payments, LLC; TOT BPS, LLC; TOT FBS, LLC; Process Pink, LLC; TOT HPS, LLC and TOT New Edge, LLC (jointly and severally, referred
to herein as “Borrower”), and

 

     

     

    

 

 

WHEREAS, the Borrower,
pursuant to the Agreement, has borrowed the principal sum of Three Million Nine Hundred Sixty-five Thousand and 00/100 dollars
($3,965,000.00) from RBL under Notes 1, 2 and 3;

 

WHEREAS, the Borrower
has requested a change in the payment terms under the Notes; and

 

WHEREAS, NETE is the
ultimate parent of the Borrower, and

 

WHEREAS, NETE will derive
direct and indirect benefit from this accommodation to Borrower by RBL; and

 

WHEREAS, it is a condition
precedent to the effectiveness of the change in payment terms that NETE shall have executed and delivered this letter agreement
to RBL for the benefit of RBL;

 

NOW, THEREFORE, in consideration
of the premises and to induce RBL to modify the payment terms of Notes 1, 2 and 3, NETE hereby agrees with and for the benefit
of RBL as follows:

 

1.Defined Terms.
Capitalized terms used, but not defined herein, shall have the meanings specified in the Agreement.

 

2.Guarantee.

 

(a)NETE hereby unconditionally
and irrevocably guarantees to RBL and its successors, endorsees, transferees and assigns, to pay and perform all the obligations,
covenants and agreements of Borrower under the Agreement and the Notes (the “Borrower’s Obligations”),
and NETE further agrees to pay any and all expenses (including, without limitation, all fees and disbursements of counsel) which
may be paid or incurred by RBL in enforcing, or obtaining advice of counsel in respect of, any rights with respect to, or collecting,
any or all of the Borrower’s Obligations and/or enforcing any rights with respect to, or collecting against, NETE under this
letter agreement.

 

(b)No payment or
payments made by the Borrower, any other NETE or any other Person or received or collected by RBL from the Borrower, any other
NETE or any other Person by virtue of any action or proceeding or any setoff or appropriation or application at any time or from
time to time in reduction of or in payment of the Borrower’s Obligations shall be deemed to modify, reduce, release or otherwise
affect the liability of NETE hereunder which shall, notwithstanding any such payment or payments other than payments made by NETE
in respect of the Borrower’s Obligations or payments received or collected from NETE in respect of the Borrower’s Obligations,
remain liable for the Borrower’s Obligations until the Borrower’s Obligations are paid in full and this letter agreement
is terminated.

 

     

     

    

 

3.No Subrogation.
Notwithstanding any payment or payments made by NETE hereunder, until all of Borrower’s Obligations have been irrevocably
and indefeasibly paid in full in cash (and therefore the payment thereof is no longer subject to being set aside or returned under
applicable law), NETE hereby agrees not to assert or enforce any claim, right or remedy which NETE may now have or may hereafter
acquire against the Borrower that arises hereunder and/or from the performance by NETE hereunder including, without limitation,
any claim, remedy or right of subrogation, reimbursement, exoneration, contribution, indemnification or participation in any claim,
right or remedy of RBL against the Borrower or any security which RBL now has or hereafter acquires, whether or not such claim,
right or remedy arises in equity, under contract, by statute, under common law or otherwise; provided that if the foregoing standstill
is not sufficient to permit indefeasible payment in full of all the Borrower’s Obligations, then NETE shall be deemed to
have waived any such claim, right or remedy to the maximum extent permitted by law.

 

4.Guarantee Absolute
and Unconditional. NETE guarantees that the Borrower’s Obligations will be paid strictly in accordance with the terms
of the Agreement, regardless of any law, regulation or order now or hereafter in effect in any jurisdiction affecting any of such
terms or the rights of RBL with respect thereto. The obligations of NETE under this letter agreement are independent of the Borrower’s
Obligations, and a separate action or actions may be brought and prosecuted against NETE to enforce this letter agreement, irrespective
of whether any action is brought against the Borrower or whether the Borrower is joined in any such action or actions. NETE understands
and agrees that this letter agreement shall be construed as a continuing, absolute and unconditional guarantee of payment without
regard to:

 

(a)the validity or
enforceability of the Agreement, any of the Obligations or any other collateral security therefore or guarantee with respect thereto
at any time or from time to time held by RBL,

 

(b)any change in
the time, manner or place of payment of, or in any other term of, all or any of the Borrower’s Obligations, or any other
amendment or waiver of or any consent to departure from the Agreement,

 

(c)any change, restructuring
or termination of the corporate structure or existence of the Borrower or any of its subsidiaries,

 

(d)any defense, setoff
or counterclaim (other than a defense of payment or performance) which may at any time be available to or be asserted by the Borrower
against RBL, or

 

(e)any other circumstance
whatsoever (with or without notice to or knowledge of the Borrower or NETE) which might otherwise constitute, or might be construed
to constitute, a defense available to, or an equitable or legal discharge of the Borrower for the Borrower’s Obligations,
or of NETE under this letter agreement, in bankruptcy or in any other instance.

 

     

     

    

 

When pursuing its rights
and remedies hereunder against NETE, RBL may, but shall be under no obligation to, pursue such rights and remedies as it may have
against the Borrower or any other Person or against any collateral security or guarantee for the obligations or any right of offset
with respect thereto, and any failure by RBL to pursue such other rights or remedies or to collect any payments from the Borrower
or any such other Person or to realize upon any such collateral security or guarantee or to exercise any such right of offset,
or any release of the Borrower or any such other Person or any such collateral security, guarantee or right of offset, shall not
relieve NETE of any liability hereunder, and shall not impair or affect the rights and remedies, whether express, implied or available
as a matter of law, of RBL against NETE. This letter agreement shall remain in full force and effect and be binding in accordance
with and to the extent of its terms upon NETE and the successors and assigns thereof, and shall inure to the benefit of RBL, and
its successors, endorsees, transferees and assigns, until all the Borrower’s Obligations and the obligations of NETE under
this letter agreement shall have been satisfied by payment in full.

 

5.Reinstatement.
This letter agreement shall continue to be effective, or be reinstated, as the case may be, if at any time payment, or any part
thereof, of any of the Borrower’s Obligations is rescinded or must otherwise be restored or returned by RBL upon the insolvency,
bankruptcy, dissolution, liquidation or reorganization of the Borrower or NETE, or upon or as a result of the appointment of a
receiver, intervenor or conservator of, or trustee or similar officer for, the Borrower or NETE or any substantial part of its
property, or otherwise, all as though such payments had not been made.

 

6.Severability.
(a) Any provision of this letter agreement which is prohibited or unenforceable in any jurisdiction shall, as to such jurisdiction,
be ineffective to the extent of such prohibition or unenforceability without invalidating the remaining provisions hereof, and
any such prohibition or unenforceability in any jurisdiction shall not invalidate or render unenforceable such provision in any
other jurisdiction.

 

(b)The parties hereto
have agreed as provided in Section 13 of this letter agreement, that New York law is to govern this letter agreement.

 

7.No Waiver: Cumulative
Remedies. RBL shall not, by any act (except by a written instrument pursuant to Section 13), delay, indulgence, omission or
otherwise, be deemed to have waived any right or remedy hereunder or to have acquiesced in any breach of the Agreement by the Borrower
or in any breach of any of the terms and conditions of this letter agreement. No failure to exercise, nor any delay in exercising,
on the part of RBL, any right, power or privilege hereunder shall operate as a waiver thereof. No single or partial exercise of
any right, power or privilege hereunder shall preclude any other or further exercise thereof or the exercise of any other right,
power or privilege. A waiver by RBL of any right or remedy hereunder on any one occasion shall not be construed as a bar to any
right or remedy which RBL would otherwise have on any future occasion. The rights and remedies herein provided are cumulative,
may be exercised singly or concurrently and are not exclusive of any rights or remedies provided by law.

 

     

     

    

 

8.Integration;
Waivers and Amendments; Successors and Assigns; Governing Law. This letter agreement represents the agreement of NETE with
respect to the subject matter hereof and there are no promises or representations by RBL relative to the subject matter hereof
not reflected herein. None of the terms or provisions of this letter agreement may be waived, amended or supplemented or otherwise
modified except by a written instrument executed by NETE and RBL; provided that any provision of this letter agreement may
be waived by RBL in a letter or agreement executed by RBL or by telex or facsimile transmission from RBL. This letter agreement
shall be binding upon the successors and assigns of NETE and shall inure to the benefit of RBL and its successors and assigns.
THIS LETTER AGREEMENT AND THE RIGHTS AND OBLIGATIONS OF THE PARTIES UNDER THIS LETTER AGREEMENT SHALL BE GOVERNED BY AND CONSTRUED
AND INTERPRETED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK WITHOUT REGARD TO THE PRINCIPLES OF CONFLICT OF LAWS THEREOF.

 

9.Notices.
All notices, requests and demands to or upon NETE or RBL to be effective shall be in writing and, unless otherwise expressly provided
herein, shall be sufficiently given if delivered in person to or sent via nationally recognized overnight delivery addressed to
a party at the address provided for such party in the Agreement or set forth under its signature below, as the case may be.

 

10.Submission
to Jurisdiction: Waivers. (a) NETE hereby irrevocably and unconditionally:

 

(i)submits
for itself and its property in any legal action or proceeding relating to this letter agreement, or for recognition and enforcement
of any judgment in respect thereof, to the exclusive jurisdiction of the courts of the State of Illinois and the courts of the
United States of America for the Northern District of New York and appellate courts from any thereof, provided, however, that RBL
may institute an action in any jurisdiction necessary to enforce its rights under this letter agreement;

 

(ii)consents
that any such action or proceeding may be brought in such courts, and waives any objection that it may now or hereafter have to
the venue of any such action or proceeding in any such court;

 

(iii)agrees
that service of process in any such action or proceeding may be effected by mailing a copy thereof by registered or certified mail
(or any substantially similar form of mail), postage prepaid, to NETE at its address set forth below or at such other address of
which RBL shall have been notified pursuant thereto; and

 

(iv)agrees
that nothing herein shall affect the right to effect service of process in any other manner permitted by law or shall limit the
right to sue in any other jurisdiction; and

 

     

     

    

 

(v)waives,
to the maximum extent not prohibited by law, any right it may have to claim or recover in any legal action or proceeding referred
to in this Section any special, exemplary, punitive or consequential damages.

 

(b)NETE AND RBL HEREBY
IRREVOCABLY AND UNCONDITIONALLY WAIVE TRIAL BY JURY IN ANY LEGAL ACTION OR PROCEEDING RELATING TO THIS LETTER AGREEMENT AND FOR
ANY COUNTERCLAIM THEREIN.

 

IN WITNESS WHEREOF,
NETE has caused the letter agreement to be duly executed by its duly authorized officer, all as of the day and year first above
written.

  

 

Respectively Yours

 

/s/ RBL Capital Group, LLC

 

 

 

 

AGREED and ACCEPTED by:

 

Net Element, Inc.

 

 

 

/s/ Oleg Firer

Oleg Firer

Title: CEO

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