Document:

Form of Stock Option Agreement

  
 Exhibit 10.7

 DIADEXUS, INC. 
 1996 STOCK OPTION PLAN 
 STOCK OPTION GRANT NOTICE 

diaDexus, Inc., a Delaware corporation, (the “Company”), pursuant to its
1996 Stock Option Plan, as amended from time to time (the “Plan”), hereby grants to the holder listed below (“Participant”), an option to purchase the number of shares of
Common Stock (as defined in the Plan) set forth below (the “Option”). This Option is subject to all of the terms and conditions set forth herein and in the Stock Option Agreement attached hereto as Exhibit
A (the “Stock Option Agreement”) and the Plan, each of which are incorporated herein by reference. Unless otherwise defined herein, the terms defined in the Plan shall have the same defined meanings in this
Grant Notice and the Stock Option Agreement. 
  

			
	 Participant:
	  	
[                             
                               ]

		
	 Grant Date:
	  	
[                             
                               ]

		
	 Exercise Price per Share:
	  	 $[                ]

		
	 Total Exercise Price:
	  	 $
[                                ]

		
	 Total Number of Shares
 Subject to the Option:
	  	
[                             
   ] shares

		
	 Expiration Date:
	  	
[                             
                               ]

		
	 Vesting Schedule:
	  	
[                             
                               ]

Type of
Option:             ̈    Incentive Stock
Option             ̈    Non-Qualified Stock Option 

By his or her signature and the Company’s signature below, Participant agrees to be bound by the terms and
conditions of the Plan, the Stock Option Agreement and this Grant Notice. Participant has reviewed the Stock Option Agreement, the Plan and this Grant Notice in their entirety, has had an opportunity to obtain the advice of counsel prior to
executing this Grant Notice and fully understands all provisions of this Grant Notice, the Stock Option Agreement and the Plan. Participant hereby agrees to accept as binding, conclusive and final all decisions or interpretations of the
Administrator upon any questions arising under the Plan, this Grant Notice or the Stock Option Agreement. 
  

									
	 DIADEXUS, INC.:
	 		 	 PARTICIPANT:

					
	 By:
	 	  
	 		 	 By:
	 	  

	 Print Name:
	 	  
	 		 	 Print Name:
	 	  

	 Title:
	 	  
	 		 		 	
	 Address:
	 	  
	 		 	 Address:
	 	  

		 	  
	 		 		 	  

  
 EXHIBIT A

 TO STOCK OPTION GRANT NOTICE 
 DIADEXUS, INC. STOCK OPTION AGREEMENT 
 Pursuant to the Stock Option Grant Notice (the “Grant Notice”) to which this Stock Option Agreement (this “Agreement”) is attached, diaDexus, Inc., a
Delaware corporation (the “Company”), has granted to the individual set forth in the Grant Notice (the “Participant”) an option (the “Option”) under the 1996 Stock Option Plan,
as amended from time to time (the “Plan”), to purchase the number of shares of Common Stock indicated in the Grant Notice. 
 ARTICLE 1. 
 GENERAL 

1.1 Defined Terms. Wherever the following terms are used in this Agreement they shall have the meanings specified
below, unless the context clearly indicates otherwise. Capitalized terms not specifically defined herein shall have the meanings specified in the Plan and the Grant Notice. 

(a) “Termination of Consultancy” shall mean the time when the engagement of Participant as a
consultant to the Company or a subsidiary of the Company (a “Subsidiary”) is terminated for any reason, with or without cause, including, but not by way of limitation, by resignation, discharge, death, Disability or
retirement, but excluding: (i) terminations where there is a simultaneous employment or continuing employment of Participant by the Company or any Subsidiary, (ii) terminations where there is a simultaneous re-establishment of a consulting
relationship or continuing consulting relationship between Participant and the Company or any Subsidiary and (iii) terminations where there is a simultaneous establishment or re-establishment of a director relationship or continuing director
relationship between Participant and the Company or any Subsidiary. The Administrator, in its absolute discretion, shall determine the effect of all matters and questions relating to Termination of Consultancy, including, but not by way of
limitation, the question of whether a particular leave of absence constitutes a Termination of Consultancy. Notwithstanding any other provision of the Plan, the Company or any Subsidiary has an absolute and unrestricted right to terminate a
consultant’s service at any time for any reason whatsoever, with or without cause, except to the extent expressly provided otherwise in writing. 
 (b) “Termination of Directorship” shall mean the time when the engagement of Participant as a member of the Board of Directors of the Company or a Subsidiary is terminated for any
reason, including, without limitation, a termination by resignation, failure to be elected, death or retirement, but excluding: (i) terminations where there is a simultaneous employment or continuing employment of Participant by the Company or
any Subsidiary, (ii) terminations where there is a simultaneous establishment or re-establishment of a consulting relationship or continuing consulting relationship between Participant and the Company or any Subsidiary and
(iii) terminations where there is a simultaneous re-establishment of a director relationship or continuing director relationship between Participant and the Company or any Subsidiary. The Board, in its sole and absolute discretion, shall
determine the effect of all matters and questions relating to Termination of Directorship with respect to Independent Directors. 

  
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 (c)
“Termination of Employment” shall mean the time when the employee-employer relationship between Participant and the Company or any Subsidiary is terminated for any reason, with or without cause, including, but not by way of
limitation, a termination by resignation, discharge, death, Disability or retirement; but excluding: (i) terminations where there is a simultaneous reemployment or continuing employment of Participant by the Company or any Subsidiary,
(ii) terminations where there is a simultaneous establishment or re-establishment of a consulting relationship or continuing consulting relationship between Participant and the Company or any Subsidiary and (iii) terminations where there
is a simultaneous establishment or re-establishment of a director relationship or continuing director relationship between Participant and the Company or any Subsidiary. The Administrator, in its absolute discretion, shall determine the effect of
all matters and questions relating to Termination of Employment, including, but not by way of limitation, the question of whether a particular leave of absence constitutes a Termination of Employment; provided, however, that, if this Option
is an Incentive Stock Option, unless otherwise determined by the Administrator in its discretion, a leave of absence, change in status from an employee to an independent contractor or other change in the employee-employer relationship shall
constitute a Termination of Employment if, and to the extent that, such leave of absence, change in status or other change interrupts employment for the purposes of Section 422(a)(2) of the Code and the then applicable regulations and revenue
rulings under said Section. 
 (d) “Termination of Services” shall mean
Participant’s Termination of Consultancy, Termination of Directorship or Termination of Employment, as applicable. 
 1.2 Incorporation of Terms of Plan. The Option is subject to the terms and conditions of the Plan which are incorporated herein by reference. In the event of any inconsistency between the Plan and
this Agreement, the terms of the Plan shall control. 
 ARTICLE 2. 

GRANT OF OPTION 
 2.1 Grant of Option. In consideration of Participant’s past and/or continued employment with or service to the Company or a Subsidiary and for other good and valuable consideration, effective
as of the Grant Date set forth in the Grant Notice (the “Grant Date”), the Company grants to Participant the Option to purchase any part or all of an aggregate of the number of shares of Common Stock set forth in the Grant
Notice, upon the terms and conditions set forth in the Plan and this Agreement, subject to adjustments as provided in Section 5(n) of the Plan. Unless designated as a Non-Qualified Stock Option in the Grant Notice, the Option shall be an
Incentive Stock Option to the maximum extent permitted by law. 
 2.2 Exercise Price. The exercise price
of the shares of Common Stock subject to the Option shall be as set forth in the Grant Notice, without commission or other charge; provided, however, that the price per share of the shares of Common Stock subject to the Option shall
not be less than 100% of the Fair Market Value of a share of Common Stock on the Grant Date. Notwithstanding the foregoing, if this Option is designated as an Incentive Stock Option and Participant owns (within the meaning of Section 424(d) of
the Code) more than 10% of the total combined voting power of all classes of stock of the Company or any “subsidiary corporation” of the Company or any “parent corporation” of the Company (each within the meaning of
Section 424 of the Code), the price per share of the shares of Common Stock subject to the Option shall not be less than 110% of the Fair Market Value of a share of Common Stock on the Grant Date. For the purposes of this Agreement,
“Fair Market Value” shall mean, as of any given date, the value of a share of Common Stock determined as follows: (a) if the Common Stock is listed on any established stock exchange (such as the New York Stock Exchange,
the NASDAQ Global Market and the NASDAQ Global Select Market) or national market system, its Fair Market Value shall be the closing sales price for a share of Common Stock as quoted on such exchange or system for such date or, if there is no closing
sales price for a share of Common Stock on the date in question, the closing sales price for a share of Common Stock on the last preceding date for which such quotation exists, as reported in The Wall Street Journal or such other source as the
Administrator deems reliable; (b) if the Common Stock is not listed on an established stock exchange or national market system, but the Common Stock is regularly quoted by a recognized securities dealer, its Fair Market Value shall be the
closing trading price for such date or, if there is no closing trading price for a share of Common Stock on such date, the closing trading price for a share of Common Stock on the last preceding date for which such information exists, as reported in
The Wall Street Journal or such other source as the Administrator deems reliable; or (b) if the Common Stock is neither listed on an established stock exchange or a national market system nor regularly quoted by a recognized securities dealer,
its Fair Market Value shall be established by the Board or such other duly-authorized administrator of the Plan (the “Administrator”) in good faith 

  
 A-2

  
 2.3
Consideration to the Company. In consideration of the grant of the Option by the Company, Participant agrees to render faithful and efficient services to the Company or any Subsidiary. Nothing in the Plan or this Agreement shall confer upon
Participant any right to continue in the employ or service of the Company or any Subsidiary or shall interfere with or restrict in any way the rights of the Company and its Subsidiaries, which rights are hereby expressly reserved, to discharge or
terminate the services of Participant at any time for any reason whatsoever, with or without cause, except to the extent expressly provided otherwise in a written agreement between the Company or a Subsidiary and Participant. 

ARTICLE 3. 

PERIOD OF EXERCISABILITY 
 3.1 Commencement of Exercisability. 
 (a) Subject to
Sections 3.2, 3.3, 5.10 and 5.15 hereof, the Option shall become vested and exercisable in such amounts and at such times as are set forth in the Grant Notice. 
 (b) No portion of the Option which has not become vested and exercisable at the date of Participant’s Termination of Services shall thereafter become vested and exercisable, except as may be
otherwise provided by the Administrator or as set forth in a written agreement between the Company and Participant. 
 (c) Notwithstanding Sections 3.1(a) hereof and the Grant Notice, but subject to Section 3.1(b) hereof, the Option shall become fully vested and exercisable with respect to all shares of Common Stock
covered thereby if any of the events specified in Section 5(o) of the Plan occur and in connection therewith the successor corporation does not assume the Option or substitute an equivalent right for the Option. Should the successor corporation
assume the Option or substitute an equivalent right, then no such acceleration shall apply. 
 3.2 Duration
of Exercisability. The installments provided for in the vesting schedule set forth in the Grant Notice are cumulative. Each such installment which becomes vested and exercisable pursuant to the vesting schedule set forth in the Grant Notice
shall remain vested and exercisable until it becomes unexercisable under Section 3.3 hereof. 
 3.3
Expiration of Option. The Option may not be exercised to any extent by anyone after the first to occur of the following events: 
 (a) The Expiration Date set forth in the Grant Notice, which shall in no event be more than ten (10) years from the Grant Date; 

  
 A-3

  
 (b) If
this Option is designated as an Incentive Stock Option and Participant owned (within the meaning of Section 424(d) of the Code), at the time the Option was granted, more than 10% of the total combined voting power of all classes of stock of the
Company or any “subsidiary corporation” of the Company or any “parent corporation” of the Company (each within the meaning of Section 424 of the Code), the expiration of five (5) years from the Grant Date; 

(c) The expiration of three (3) months from the date of Participant’s Termination of Services, unless such
termination occurs by reason of Participant’s death or Disability; or 
 (d) The expiration of one
(1) year from the date of Participant’s Termination of Services by reason of Participant’s death or Disability. 
 The Participant acknowledges that an Incentive Stock Option exercised more than three (3) months after the Participant’s Termination of Employment, other than by reason of Death or Disability
will be taxed as a Non-Qualified Stock Option. 
 3.4 Special Tax Consequences. Participant acknowledges
that, to the extent that the aggregate Fair Market Value (determined as of the time the Option is granted) of all shares of Common Stock with respect to which Incentive Stock Options, including the Option (if applicable), are exercisable for the
first time by Participant in any calendar year exceeds $100,000, the Option and such other options shall be Non-Qualified Stock Options to the extent necessary to comply with the limitations imposed by Section 422(d) of the Code. Participant
further acknowledges that the rule set forth in the preceding sentence shall be applied by taking the Option and other “incentive stock options” into account in the order in which they were granted, as determined under Section 422(d)
of the Code and the Treasury Regulations thereunder. Participant also acknowledges that an Incentive Stock Option exercised more than three (3) months after Participant’s Termination of Employment, other than by reason of death or
Disability, will be taxed as a Non-Qualified Stock Option. 
 ARTICLE 4. 

EXERCISE OF OPTION 
 4.1 Person Eligible to Exercise. During the lifetime of Participant, only Participant may exercise the Option or any portion thereof. After the death of Participant, any exercisable portion of the
Option may, prior to the time when the Option becomes unexercisable under Section 3.3 hereof, be exercised by Participant’s personal representative or by any person empowered to do so under the deceased Participant’s will or under the
then applicable laws of descent and distribution. 
 4.2 Partial Exercise. Any exercisable portion of the
Option or the entire Option, if then wholly exercisable, may be exercised in whole or in part at any time prior to the time when the Option or portion thereof becomes unexercisable under Section 3.3 hereof. 

4.3 Manner of Exercise. The Option, or any exercisable portion thereof, may be exercised solely by delivery to the
Secretary of the Company (or any third party administrator or other person or entity designated by the Company), during regular business hours, of all of the following prior to the time when the Option or such portion thereof becomes unexercisable
under Section 3.3 hereof: 
 (a) An exercise notice in a form specified by the Administrator, stating that
the Option or portion thereof is thereby exercised, such notice complying with all applicable rules established by the Administrator; 

  
 A-4

  
 (b)
The receipt by the Company of full payment for the shares of Common Stock with respect to which the Option or portion thereof is exercised, including payment of any applicable withholding tax, which shall be made by deduction from other compensation
payable to Participant or in such other form of consideration permitted under Section 4.4 hereof that is acceptable to the Company; 
 (c) Any other written representations as may be required in the Administrator’s reasonable discretion to evidence compliance with the Securities Act of 1933, as amended (the “Securities
Act”), or any other applicable law, rule or regulation; and 
 (d) In the event the Option or
portion thereof shall be exercised pursuant to Section 4.1 hereof by any person or persons other than Participant, appropriate proof of the right of such person or persons to exercise the Option. 

Notwithstanding any of the foregoing, the Company shall have the right to specify all conditions of the manner of exercise, which
conditions may vary by country and which may be subject to change from time to time. 
 4.4 Method of
Payment. Payment of the exercise price shall be by any of the following, or a combination thereof, at the election of Participant: 
 (a) Cash or check; 
 (b) With the consent of the Administrator,
surrender of shares of Common Stock (including, without limitation, shares of Common Stock otherwise issuable upon exercise of the Option) held for such period of time as may be required by the Administrator in order to avoid adverse accounting
consequences and having a Fair Market Value on the date of delivery equal to the aggregate exercise price of the Option or exercised portion thereof; or 
 (c) Other property acceptable to the Administrator (including, without limitation, through the delivery of a notice that Participant has placed a market sell order with a broker with respect to shares of
Common Stock then issuable upon exercise of the Option, and that the broker has been directed to pay a sufficient portion of the net proceeds of the sale to the Company in satisfaction of the Option exercise price; provided that payment of
such proceeds is then made to the Company at such time as may be required by the Company, but in any event not later than the settlement of such sale). 
 4.5 Conditions to Issuance of Common Stock. The shares of Common Stock deliverable upon the exercise of the Option, or any portion thereof, may be either previously authorized but unissued shares
of Common Stock or issued shares of Common Stock which have then been reacquired by the Company. Such shares of Common Stock shall be fully paid and nonassessable. The Company shall not be required to issue or deliver any shares of Common Stock
purchased upon the exercise of the Option or portion thereof prior to fulfillment of all of the following conditions: 
 (a) The admission of such shares of Common Stock to listing on all stock exchanges on which such Common Stock is then listed; 

(b) The completion of any registration or other qualification of such shares of Common Stock under any state or federal
law or under rulings or regulations of the Securities and Exchange Commission or of any other governmental regulatory body, which the Administrator shall, in its absolute discretion, deem necessary or advisable; 

  
 A-5

  
 (c)
The obtaining of any approval or other clearance from any state or federal governmental agency which the Administrator shall, in its absolute discretion, determine to be necessary or advisable; 

(d) The receipt by the Company of full payment for such shares of Common Stock, including payment of any applicable
withholding tax, which may be in one or more of the forms of consideration permitted under Section 4.4 hereof; and 
 (e) The lapse of such reasonable period of time following the exercise of the Option as the Administrator may from time to time establish for reasons of administrative convenience. 

4.6 Rights as Stockholder. The holder of the Option shall not be, nor have any of the rights or privileges of, a
stockholder of the Company, including, without limitation, voting rights and rights to dividends, in respect of any shares of Common Stock purchasable upon the exercise of any part of the Option unless and until such shares of Common Stock shall
have been issued by the Company and held of record by such holder (as evidenced by the appropriate entry on the books of the Company or of a duly authorized transfer agent of the Company). No adjustment will be made for a dividend or other right for
which the record date is prior to the date the shares of Common Stock are issued, except as provided in Section 5(n) of the Plan. 
 ARTICLE 5. 
 OTHER PROVISIONS 

5.1 Administration. The Administrator shall have the power to interpret the Plan and this Agreement and to adopt
such rules for the administration, interpretation and application of the Plan as are consistent therewith and to interpret, amend or revoke any such rules. All actions taken and all interpretations and determinations made by the Administrator in
good faith shall be final and binding upon Participant, the Company and all other interested persons. No member of the Committee or the Board shall be personally liable for any action, determination or interpretation made in good faith with respect
to the Plan, this Agreement or the Option. 
 5.2 Whole Shares. The Option may only be exercised for
whole shares of Common Stock. 
 5.3 Option Not Transferable. Subject to Section 4.1 hereof, the
Option may not be sold, pledged, assigned or transferred in any manner other than by will or the laws of descent and distribution, unless and until the shares of Common Stock underlying the Option have been issued, and all restrictions applicable to
such shares of Common Stock have lapsed. Neither the Option nor any interest or right therein shall be liable for the debts, contracts or engagements of Participant or his or her successors in interest or shall be subject to disposition by transfer,
alienation, anticipation, pledge, encumbrance, assignment or any other means whether such disposition be voluntary or involuntary or by operation of law by judgment, levy, attachment, garnishment or any other legal or equitable proceedings
(including bankruptcy), and any attempted disposition thereof shall be null and void and of no effect, except to the extent that such disposition is permitted by the preceding sentence. 

5.4 Binding Agreement. Subject to the limitation on the transferability of the Option contained herein, this
Agreement will be binding upon and inure to the benefit of the heirs, legatees, legal representatives, successors and assigns of the parties hereto. 
 5.5 Adjustments Upon Specified Events. The Administrator may accelerate the vesting of the Option in such circumstances as it, in its sole discretion, may determine. In addition, upon the
occurrence of certain events relating to the Common Stock contemplated by Section 5(n) of the Plan (including, without limitation, an extraordinary cash dividend on such Common Stock), the Administrator shall make such adjustments the
Administrator deems appropriate in the number of shares of Common Stock subject to the Option, the exercise price of the Option and the kind of securities that may be issued upon exercise of the Option. Participant acknowledges that the Option is
subject to adjustment, modification and termination in certain events as provided in this Agreement and Section 5(n) of the Plan. 

  
 A-6

  
 5.6
Notices. Any notice to be given under the terms of this Agreement to the Company shall be addressed to the Company in care of the Secretary of the Company at the Company’s principal office, and any notice to be given to Participant shall
be addressed to Participant at Participant’s last address reflected on the Company’s records. By a notice given pursuant to this Section 5.6, either party may hereafter designate a different address for notices to be given to that
party. Any notice which is required to be given to Participant shall, if Participant is then deceased, be given to the person entitled to exercise his or her Option pursuant to Section 4.1 hereof by written notice under this Section 5.6.
Any notice shall be deemed duly given when sent via email or when sent by certified mail (return receipt requested) and deposited (with postage prepaid) in a post office or branch post office regularly maintained by the United States Postal Service.

 5.7 Titles. Titles are provided herein for convenience only and are not to serve as a basis for
interpretation or construction of this Agreement. 
 5.8 Governing Law. The laws of the State of Delaware
shall govern the interpretation, validity, administration, enforcement and performance of the terms of this Agreement regardless of the law that might be applied under principles of conflicts of laws. 

5.9 Conformity to Securities Laws. Participant acknowledges that the Plan and this Agreement are intended to
conform to the extent necessary with all provisions of the Securities Act and the Exchange Act and any and all regulations and rules promulgated by the Securities and Exchange Commission thereunder, and state securities laws and regulations.
Notwithstanding anything herein to the contrary, the Plan shall be administered, and the Option is granted and may be exercised, only in such a manner as to conform to such laws, rules and regulations. To the extent permitted by applicable law, the
Plan and this Agreement shall be deemed amended to the extent necessary to conform to such laws, rules and regulations. 
 5.10 Amendments, Suspension and Termination. To the extent permitted by the Plan, this Agreement may be wholly or partially amended or otherwise modified, suspended or terminated at any time or
from time to time by the Committee or the Board; provided that, except as may otherwise be provided by the Plan, no amendment, modification, suspension or termination of this Agreement shall adversely affect the Option in any material way
without the prior written consent of Participant. 
 5.11 Successors and Assigns. The Company may assign
any of its rights under this Agreement to single or multiple assignees, and this Agreement shall inure to the benefit of the successors and assigns of the Company. Subject to the restrictions on transfer herein set forth in Section 5.3 hereof,
this Agreement shall be binding upon Participant and his or her heirs, executors, administrators, successors and assigns. 
 5.12 Notification of Disposition. If this Option is designated as an Incentive Stock Option, Participant shall give prompt notice to the Company of any disposition or other transfer of any shares
of Common Stock acquired under this Agreement if such disposition or transfer is made (a) within two (2) years from the Grant Date with respect to such shares of Common Stock or (b) within one (1) year after the transfer of such
shares of Common Stock to Participant. Such notice shall specify the date of such disposition or other transfer and the amount realized, in cash, other property, assumption of indebtedness or other consideration, by Participant in such disposition
or other transfer. 

  
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 5.13
Limitations Applicable to Section 16 Persons. Notwithstanding any other provision of the Plan or this Agreement, if Participant is subject to Section 16 of the Exchange Act, the Plan, the Option and this Agreement shall be subject
to any additional limitations set forth in any applicable exemptive rule under Section 16 of the Exchange Act (including any amendment to Rule 16b-3 of the Exchange Act) that are requirements for the application of such exemptive rule. To the
extent permitted by applicable law, this Agreement shall be deemed amended to the extent necessary to conform to such applicable exemptive rule. 
 5.14 Entire Agreement. The Plan, the Grant Notice and this Agreement (including all Exhibits thereto) constitute the entire agreement of the parties and supersede in their entirety all prior
undertakings and agreements of the Company and Participant with respect to the subject matter hereof. 
 5.15
Section 409A. This Option is not intended to constitute “nonqualified deferred compensation” within the meaning of Section 409A of the Code (together with any Department of Treasury regulations and other interpretive
guidance issued thereunder, including without limitation any such regulations or other guidance that may be issued after the date hereof, “Section 409A”). However, notwithstanding any other provision of the Plan, the Grant
Notice or this Agreement, if at any time the Administrator determines that the Option (or any portion thereof) may be subject to Section 409A, the Administrator shall have the right in its sole discretion (without any obligation to do so or to
indemnify Participant or any other person for failure to do so) to adopt such amendments to the Plan, the Grant Notice or this Agreement, or adopt other policies and procedures (including amendments, policies and procedures with retroactive effect),
or take any other actions, as the Administrator determines are necessary or appropriate either for the Option to be exempt from the application of Section 409A or to comply with the requirements of Section 409A. 

5.16 Limitation on Participant’s Rights. Participation in the Plan confers no rights or interests other than
as herein provided. This Agreement creates only a contractual obligation on the part of the Company as to amounts payable and shall not be construed as creating a trust. Neither the Plan nor any underlying program, in and of itself, has any assets.
Participant shall have only the rights of a general unsecured creditor of the Company with respect to amounts credited and benefits payable, if any, with respect to the Option, and rights no greater than the right to receive the Common Stock as a
general unsecured creditor with respect to options, as and when exercised pursuant to the terms hereof. 

  
 A-8diaDexus, Inc. Retention Bonus Plan

  
 Exhibit 10.8

 DIADEXUS, INC. 
 RETENTION BONUS PLAN 
 (Amended and Restated May 1,
2008, May 27, 2010 and June 24, 2010) 
 1. Purpose. The purpose of the Plan, as amended and restated
herein, is to reinforce and encourage the continued attention and dedication of employees of the Company by providing retention bonus payments to such employees upon the consummation of a Change in Control. 

2. Definitions. The following terms as used herein shall have the meanings set forth in this Section 2. 

2.1 “Acquirer” shall mean any successor to the business or assets of the Company pursuant to a Change in Control.

 2.2 “Acquisition Agreement” shall mean any agreement entered into by the Company which, if consummated,
would result in a Change in Control. 
 2.3 “Board” shall mean the Board of Directors of the Company, as
constituted from time to time. 
 2.4 “Bona Fide Offer” shall mean a written offer delivered to the Company
which specifies, at a minimum, the principal terms of the proposed Change in Control, including, without limitation, the aggregate Proceeds to the Company’s stockholders, the proposed structure of the Change in Control and any major conditions
to closing. 
 2.5 “Bonus Pool Amount” shall mean an amount determined as follows: 

(a) If the Proceeds upon a Change in Control have a value less than or equal to $75,000,000 then the Bonus Pool Amount
shall be equal to 8% of the Proceeds. 
 (b) If the Proceeds upon a Change in Control have a value greater than
$75,000,000, then the Bonus Pool Amount shall be equal to 12% of the Proceeds. 
 2.6 “Cause” shall be as
defined in any employment, severance or similar agreement between the Participant and the Company; provided, that in the absence of an employment, severance or similar agreement containing such definition, Cause shall mean: 

(a) A material act of dishonesty made by the Participant in connection with the Participant’s responsibilities as an
employee; 
 (b) The Participant’s commission of, or plea of nolo contendere to, a felony;

  
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 (c) The
Participant’s gross misconduct in connection with the performance of his or her duties as an Employee; or 

(d) The Participant’s material breach of his or her obligations under any written agreement with the Company;

 provided, however, that with respect to clauses (c) and (d), such actions shall not constitute Cause if they are cured by the
Participant within thirty (30) days following delivery to the Participant of a written explanation specifying the basis for the Company’s beliefs with respect to such clauses. 

2.7 “Change in Control” shall mean (a) the acquisition of the Company by another entity, or entities acting as a
group, by means of any transaction or series of related transactions (including, without limitation, any reorganization, merger or consolidation) that results in such entity or entities holding more than fifty percent (50%) of the outstanding
voting power of the Company (other than a bona fide equity financing transaction or transfers between affiliated funds) or (b) a sale or transfer of all or substantially all of the assets of this corporation, which transaction or series of
related transactions results in the payment of a Liquidation Preference pursuant to Section 2 of the Restated Certificate of Incorporation of the Company. 
 2.8 “Code” shall mean the Internal Revenue Code of 1986, as amended. 
 2.9 “Common Stock” shall mean the Common Stock of the Company, par value $0.01 per share. 
 2.10 “Company” shall mean diaDexus, Inc., a Delaware corporation. 

2.11 “Compensation Committee” shall mean the Compensation Committee of the Board. 

2.12 “Covered Termination” shall mean the termination of Participant’s employment or service with the Company by
the Company for other than Cause or by the Participant for Good Reason that constitutes a “separation from service” within the meaning of Section 409A of the Code and the Department of Treasury regulations and other guidance
promulgated thereunder. 
 2.13 “Employee” shall mean an individual who is an employee of the Company or any
Subsidiary within the meaning of Section 3401(c) of the Code. 
 2.14 “Equity Offset” shall mean any net
pre-tax gains in respect of Common Stock received by a Participant in connection with the Change in Control, including but not limited to amounts received with respect to such Participant’s outstanding restricted Common Stock or options to
purchase Common Stock. 

  
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 2.15 “Good
Reason” shall mean the Participant having “Good Reason” to voluntarily terminate his employment, as defined in any employment, severance or similar agreement between the Participant and the Company; provided, that in the absence
of an employment, severance or similar agreement containing such definition, the Participant shall have Good Reason to voluntarily terminate his or her employment or service following any of the following events unless the Company fully corrects the
circumstances giving rise to the event (provided such circumstances are capable of correction) prior to the date of the Participant’s termination: 
 (a) Any material reduction of the Participant’s base compensation without the Participant’s express written consent; 

(b) Any material reduction in the Participant’s title, authority or duties; or 

(c) The relocation of the Company’s offices at which the Participant is principally employed or provides services to
a location a material distance of more than thirty (30) miles from such offices without the Participant’s express written consent; or 
 (d) The Company’s material breach of its obligations under this Plan. 

Provided, however, that notwithstanding the foregoing the Participant may not resign his employment with Good Reason unless:
(1) the Participant provides the Company with at least thirty (30) days prior written notice of his intent to resign for Good Reason (which notice is provided not later than the 30th day following the occurrence of the event constituting Good Reason and contains reasonable detail regarding the basis
for asserting Good Reason) and (2) the Company has not remedied the violation(s) within the thirty (30) day period. Additionally, a Participant’s continued employment or service shall not constitute consent to, or a waiver of rights
with respect to, any circumstance described above which may give rise to a termination with Good Reason. 
 2.16
“Officer” shall mean an Employee who has been designated an officer of the Company by the Board. 
 2.17
“Participant” shall mean an Employee who has been selected by the Administrator to receive a Retention Bonus pursuant to the Plan. 
 2.18 “Percentage Interest” shall mean a grant to a Participant, pursuant to this Plan, of a percentage of the Bonus Pool Amount as determined in the sole discretion of the Compensation
Committee prior to a Change in Control. 
 2.19 “Plan” shall mean this diaDexus, Inc. Retention Bonus Plan, as
amended and restated herein. 
 2.20 “Proceeds” shall mean the following items of consideration (in cash,
securities or other property) paid by the Acquirer in effecting the Change in Control: 
 (a) For a Change in
Control effected by a merger or consolidation or by the direct purchase of the Company’s outstanding securities, the aggregate amount of consideration (valued at fair market value by the Board in good faith) to be paid to the holders of the
Company’s outstanding securities in the acquisition of their stockholder interests, or 

  
 3 

  
 (b) For
a Change in Control effected by the purchase of all or substantially all of the Company’s assets, the portion of the consideration (valued at fair market value by the Board in good faith) to be paid to the Company for those assets that is to be
subsequently distributed to the holders of the Company’s outstanding securities in liquidation of their stockholder interests. 
 No
expense or liability of the Company assumed or discharged by the Company or the Acquirer in the Change in Control, including without limitation the payment of Retention Bonuses hereunder, will be taken into account in determining the amount of
Proceeds. 
 Proceeds shall also include any and all holdbacks, escrows, earn-out provisions, other contingent pay-out features or other similar
delays in payment to be made after the effective date of the Change in Control. 
 2.21 “Retention Bonus” shall
mean a bonus payable to a Participant pursuant to the terms of this Plan. 
 2.22 “Retention Bonus Amount”
shall mean, with respect to a Participant, (i) the Bonus Pool Amount multiplied by such Participant’s Percentage Interest, minus (ii) the Equity Offset. For the purposes of calculating the Bonus Pool Amount with respect to any
Participant who is not an Officer, any Proceeds subject to holdback, escrow, earn-out or other contingency shall be valued at one hundred percent (100%) of the amount subjected to holdback, escrow, earn-out or other contingency. For the
purposes of calculating the Bonus Pool Amount with respect to a Participant who is an Officer, any Proceeds subject to holdback, escrow, earn-out or other contingency shall be valued at the amount actually paid to stockholders or the Company from
such holdback, escrow, earn-out or other contingency. 
 2.23 “Subsidiary” shall have the meaning set forth in
Section 424(f) of the Code. 
 3. Administration. 

3.1 Administrator. The Plan shall be administered by the Compensation Committee. The Compensation Committee acting as
administrator of the Plan may be hereafter referred to as the “Administrator.” 
 3.2 Authority of the
Administrator. Subject to the provisions of the Plan and the Company’s Certificate of Incorporation, as they may be amended from time to time, the Administrator shall have full authority and discretion to take any actions it deems necessary
or advisable for the administration of the Plan. Subject to the provisions of the Plan, the Administrator has authority to determine, in its sole discretion, to whom, and the time or times at which, Retention Bonuses may be paid as well as the
allocation of Percentage Interests. Subject to the Company’s Certificate of Incorporation, as may be amended from time to time, the Administrator has authority to prescribe, amend and rescind rules and regulations relating to the Plan and to
make all other determinations necessary or advisable for Plan administration. All decisions, interpretations and other actions of the Administrator shall be final, conclusive and binding on all parties who have an interest in the Plan. 

  
 4 

  
 3.3 Administrator
Liability. No member of the Compensation Committee will be liable for any action or determination made by the Compensation Committee with respect to the Plan or any Retention Bonus paid under the Plan. All expenses and liabilities which members
of the Compensation Committee incur in connection with the administration of this Plan shall be borne by the Company or its successor. No members of the Compensation Committee shall be personally liable for any action, determination or
interpretation made in good faith with respect to this Plan or any Retention Bonuses paid hereunder, and all members of the Compensation Committee shall be fully indemnified and held harmless by the Company or its successor in respect of any such
action, determination or interpretation. 
 4. Eligibility. Only Employees shall be eligible to participate in the Plan.
The Administrator shall determine the Participants in its sole discretion. Only Participants shall be eligible to receive a Retention Bonus pursuant to this Plan. 
 5. Terms and Conditions of the Retention Bonuses. 
 5.1 Allocation of
Aggregate Amount of Retention Bonuses. The allocation of the Percentage Interests to be awarded hereunder shall be determined prior to the consummation of a Change in Control by the Administrator. In advance of any determination by the
Administrator regarding the individual amounts to be allocated under the Plan to the various Participants, the Company’s Chief Executive Officer shall have the opportunity to make a presentation and recommendation to the Administrator regarding
such allocations. The Administrator may, in its sole discretion, notify each Participant of his or her Percentage Interest allocation at any time after making such determination. Any Percentage Interest granted by the Compensation Committee which is
subsequently forfeited shall be reallocated to the Bonus Pool Amount and be available for allocation at the sole discretion of the Compensation Committee. Any portion of the Bonus Pool Amount which remains un-allocated as of the consummation of the
Change in Control shall not be distributed automatically to the existing Participants and shall remain assets of the Company and its successors. 
 5.2 Payment of Retention Bonuses. Subject to Section 5.3 below, each Participant shall be entitled to his or her Retention Bonus upon the consummation of the Change in Control. Subject to
Section 5.3 below, all payments under the Plan to Participants who are not Officers shall be made within 30 days after the consummation of the Change in Control and payments under the Plan made to Officers shall be made within 30 days following
the date related Proceeds first become payable to stockholders or the Company. Except as otherwise provided in Section 5.3, a Participant must remain in the continuous employment or other service of the Company through the date of each payment
in order to be eligible for such payment. The Retention Bonus shall be determined by the Administrator in accordance with this Plan and shall be in an amount equal to the Retention Bonus Amount. The Retention Bonus shall be payable in cash or, as
permitted solely in the Administrator’s discretion with respect to each Participant at any time prior to such payment, such other form (or forms) of consideration being paid to shareholders in connection with the Change in Control, but in the
event that all or a portion of the consideration consists of other than cash or securities that are freely tradable at the time of their issuance (“Public Securities”), the Retention Bonus will be payable in cash at least to the
extent sufficient to permit such Participant to satisfy his or her state, local and federal income tax and employment tax withholding liabilities with respect to his or her Retention Bonus as calculated based on the statutory withholding tax rates
in effect for such payments at the time the Retention Bonus is paid. 

  
 5 

  
 5.3 Involuntary
Termination. Notwithstanding Sections 5.1 and 5.2 above, in the event of a Participant’s Covered Termination during the period of time commencing upon a Bona Fide Offer and ending upon the date all payments under this Plan have been made or
the date this Plan shall have been terminated in accordance with its terms, such Participant shall be entitled to receive his or her Retention Bonus Amount payable in a cash lump sum as soon as administratively practicable following the date of the
consummation of the Change in Control or, with respect to Officers, as soon as administratively practicable after the date related payments of Proceeds are first made available to stockholders or the Company. In the event the Bona Fide Offer is
revoked or otherwise terminated without the consummation of a transaction constituting a Change in Control, a Participant’s rights with respect to such Bona Fide Offer shall thereupon be forfeited for no consideration. 

6. Assumption of Plan. The Company shall require any successor (whether direct or indirect, by purchase, merger, consolidation or
otherwise) to all or substantially all of the business and/or assets of the Company, whether pursuant to a Change in Control or otherwise, to expressly assume and agree to perform the obligations under this Plan in the same manner and to the same
extent the Company would be required to perform if no such succession had taken place. 
 7. Withholding Taxes. All
amounts payable hereunder shall be subject to applicable state, federal and local income, employment and excise tax withholding. 
 8. Assignment or Transfer of Awards. The Company may assign this Plan and its rights and obligations hereunder in whole, but not in part, only to any corporation or other entity with or into which
the Company may hereafter merge or consolidate or to which the Company may transfer all or substantially all of its assets if, in any such case, said corporation or other entity shall by operation of law or expressly in writing assume all
obligations of the Company hereunder as fully as if it had been originally made a party hereto; the Company may not otherwise assign this Plan or any of its rights and obligations hereunder. Subject to the foregoing, the terms and provisions of this
Plan shall be binding upon any successor to the Company (including without limitation, any Acquirer), and such successor shall accordingly be liable for the payment of all benefits which become due and payable under the Plan with respect to the
Participants. No Participant’s rights hereunder shall be anticipated, assigned, attached, garnished, optioned, transferred or made subject to any creditor’s process, whether voluntarily, involuntarily or by operation of law, except as
approved by the Administrator. 
 9. No Employment Rights. No provision of the Plan shall be construed to give any person
any right to become, to be treated as, or to remain an Employee. The Company and its Subsidiaries reserve the right to terminate any Participant’s employment at any time and for any reason or for no reason, with or without cause and with or
without advance notice. 

  
 6 

  
 10. No Equity
Interest. Neither the Plan nor any allocation of Percentage Interests hereunder creates or conveys any equity or ownership interest in the Company nor any rights commonly associated with such interests, including, without limitation, the right
to vote on any matters put before the stockholders of the Company. 
 11. Duration and Amendments. 

11.1 Term of the Plan. This Plan shall be effective as of November 10, 2006 and shall terminate upon the earlier to occur of
(a) the payment of all amounts payable hereunder; or (b) the closing of an initial public offering of the Company’s Common Stock. For the avoidance of doubt, the closing of an initial public offering of the Common Stock of any
successor to the Company shall not be deemed to terminate the Plan. 
 11.2 Subsequent Financings by the Company. In the
event that the Board determines in good faith that the Company has undergone a financing for cash subsequent to the adoption of the Plan, such that the Plan should be amended to take into account such financing, the Company and the Participants
holding at least a majority of the Percentage Interests held by all Participants shall negotiate in good faith to amend the Plan to appropriately reflect the impact of the financing on the Plan. 

11.3 Right to Amend the Plan. Except as provided herein and in the Company’s Certificate of Incorporation, as may be amended
from time to time, the Plan may be amended at any time or from time to time by the Board; provided, however, that no such amendment shall impair the then-existing rights of a Participant with regard to the Plan (including without
limitation his or her rights to properly allocated Percentage Interests) absent (a) his or her consent or (b) the approval by the Participants holding at least a majority of the Percentage Interests held by all Participants.
Notwithstanding the foregoing, in the event of any amendment to the Plan that causes Retention Bonuses to be payable in any form other than cash or Public Securities, each Participant’s Retention Bonus shall nonetheless be payable in cash or
Public Securities in an amount that is no less than the amount sufficient to permit such Participant to satisfy his or her state, local and federal income tax and employment tax withholding liability with respect to his or her Retention Bonus. For
purposes of determining the amount of any Participant’s Retention Bonus that is required to be paid in cash or Public Securities pursuant to the immediately preceding sentence, the Company shall use the statutory rate of withholding for the
Participant with respect to the payment of such Retention Bonus. This Section 11.3 may only be amended with the unanimous consent of the Participants then holding Percentage Interests. 

12. Execution. To record the adoption of the Plan, the Company has caused its authorized officer to execute the same. 

13. Choice of Law. All questions concerning the construction, validation and interpretation of the Plan will be governed by the
law of the State of Delaware without regard to its conflict of laws provision. 

  
 7 

  
 14. Funding. No
provision of the Plan shall require the Company, for purpose of satisfying any obligations under the Plan, to purchase assets or place any assets in a trust or other entity to which contributions are made or otherwise to segregate any assets, nor
shall the Company maintain separate bank accounts, books, records or other evidence of the existence of a segregated or separately maintained or administered fund for such purposes. Participants shall have no rights under the Plan other than as
unsecured general creditors of the Company or its successor. 
  

			
	diaDexus, Inc.
		
	By:	 	 /s/ Patrick Plewman

		
	Title:	 	 President and CEO

  
 8

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