Document:

Amendment to Offer Letter - Jean-Frederic Viret

 Exhibit 10.81 
 

 
 November 17, 2008 
 Jean-Frederic Viret 
 Dear Jean: 
 Anesiva, Inc. (the “Company”) is pleased to offer you an amendment (the “Amendment”) to your employment terms, as set forth in the offer letter between you and the Company, dated November 21, 2002 (the “Offer
Letter”). The employment terms set forth in this Amendment are effective as of November 17, 2008 (the “Amendment Date”). Unless this Amendment specifically states that it supersedes a term in the Offer Letter, the terms of the
Offer Letter shall remain binding and in full force and effect. 
 1. Retention Bonus. You will be eligible to receive a Retention
Bonus in an amount equal to two (2) months of your base salary currently in effect, to be earned and payable on the following schedule: (i) 50% of the bonus on November 17, 2008, (ii) 25% of the bonus on November 26, 2008,
and (iii) 25% of the bonus on December 15, 2008. 
 In the event that you resign from employment with the Company for any reason
before February 9, 2009, you agree that you will repay to the Company this Retention Bonus amount paid to you (“Retention Repayment Amount”) pursuant to this Section. Any Retention Repayment Amount that must be repaid pursuant to this
paragraph will be paid within thirty (30) days following your last date of employment with the Company. 
 In the event that you are
involuntarily terminated from employment with the Company, you will not be liable for repayment of the Retention Bonus. 
 2. Employment
Relationship. Your employment with the Company is and continues to be “at will” as described in your Offer Letter. 
 3. Supersedes. This Amendment supersedes and replaces any prior agreements, representations or understandings, whether written, oral or implied, between you and the Company regarding this subject matter described herein, provided
that unless specifically superseded by this Amendment, the terms of the Offer Letter remain in full force and effect. 
 We hope that you
find the forgoing terms acceptable. You may indicate your agreement with these terms and accept this Amendment by signing and dating the Amendment and returning it to me. 
  

			
	Very truly yours,
	
	ANESIVA, INC.
		
	By:	 	/s/ Michael L. Kranda
		 	Michael L. Kranda
		 	President & Chief Executive Officer

 I have read, and accept and agree to, the terms of this Amendment to my Offer Letter: 
  

	
	/s/ Jean-Frederic Viret
	Jean-Frederic Viret

 Dated: 11-18-08Amendment to Offer Letter - Michael L. Kranda

 Exhibit 10.82 
 

 
 November 17, 2008 
 Michael
L. Kranda 
 Dear Michael: 
 Anesiva, Inc. (the
“Company”) is pleased to offer you an amendment (the “Amendment”) to your employment terms, as set forth in the offer letter between you and the Company, dated June 16, 2008 (the “Offer Letter”). The employment
terms set forth in this Amendment are effective as of November 17, 2008 (the “Amendment Date”). Unless this Amendment specifically states that it supersedes a term in the Offer Letter, the terms of the Offer Letter shall remain
binding and in full force and effect. 
 1. Retention Bonus. You will be eligible to receive a Retention Bonus in an amount equal to
two (2) months of your base salary currently in effect, to be earned and payable on the following schedule: (i) 50% of the bonus on November 17, 2008, (ii) 25% of the bonus on November 26, 2008, and (iii) 25% of the
bonus on December 15, 2008. 
 In the event that you resign from employment with the Company for any reason before February 9,
2009, you agree that you will repay to the Company this Retention Bonus amount paid to you (“Retention Repayment Amount”) pursuant to this Section. Any Retention Repayment Amount that must be repaid pursuant to this paragraph will be paid
within thirty (30) days following your last date of employment with the Company. 
 In the event that you are involuntarily terminated
from employment with the Company, you will not be liable for repayment of the Retention Bonus. 
 2. Employment Relationship.
Your employment with the Company is and continues to be “at will” as described in Section 10 of the Offer Letter. 
 3.
Supersedes. This Amendment supersedes and replaces any prior agreements, representations or understandings, whether written, oral or implied, between you and the Company regarding this subject matter described herein, provided that unless
specifically superseded by this Amendment, the terms of the Offer Letter remain in full force and effect. 
 We hope that you find the
forgoing terms acceptable. You may indicate your agreement with these terms and accept this Amendment by signing and dating the Amendment and returning it to me. 
  

			
	Very truly yours,
	
	ANESIVA, INC.
		
	By:	 	/s/ Jean-Frederic Viret
		 	Jean-Frederic Viret
		 	 Vice President & Chief Financial Officer

 I have read, and accept and agree to, the terms of this Amendment to my Offer Letter: 
  

	
	/s/ Michael L. Kranda
	Michael L. Kranda

 Dated: 11-19-08Retention Bonus Letter - Michael L. Kranda

 Exhibit 10.83 
 

 
 Delivered in Person 
 February 25, 2009 
 Michael Kranda 
 Dear
Michael: 
 As you know, given the macro economic climate and resulting impact on company operations, many corporations have scaled back and
even eliminated 2008 bonus programs as was the decision by Anesiva’s Board of Directors. However, in recognition of the continued commitment of its people to the success of the company, the Board has adopted a retention bonus plan for 2009.
Anesiva, Inc. (the “Company”) is pleased to offer you an initial bonus payment in the amount equal to Sixty-six Thousand Six Hundred Sixty-seven Dollars ($66,667.00) to be earned and payable on March 1, 2009. Additional stay bonuses
are planned for May and June under similar terms subject to subsequent Board approval. 
 In the event that you voluntarily resign from
employment with the Company before May 1, 2009, you agree that you will repay to the Company this retention bonus amount paid to you pursuant to this letter. Any repayment under this paragraph must be repaid within thirty (30) days
following your last date of employment with the Company. In the event that you are involuntarily terminated from employment with the Company, you will not be liable for repayment of the retention bonus. 
 As a reminder, your employment with the Company continues to be “at will,” as described in your original Offer Letter. This retention bonus and
letter does not change any other terms of your Offer Letter. 
 We hope that you find the foregoing terms acceptable. Please indicate your
agreement with these terms by signing and dating below. 
  

	
	Sincerely,
	
	/s/ John Tran
	John Tran
	Vice President, Finance

 I have read, accept and agree to, the terms of this agreement. 
  

					
	/s/ Michael L. Kranda	 		 	2/25/2009
	Name	 		 	Date

 HEADQUARTERS: 
 650 GATEWAY BOULEVARD, SOUTH SAN FRANCISCO, CA 94080 • PHONE (650) 624-9600 • FAX (650) 624-7540 
 WWW.ANESIVA.COMRetention Bonus Letter - William C. Houghton

 Exhibit 10.84 
 

 
 Delivered in Person 
 February 25, 2009 
 William Houghton 
 Dear Bill:

 As you know, given the macro economic climate and resulting impact on company operations, many corporations have scaled back and even
eliminated 2008 bonus programs as was the decision by Anesiva’s Board of Directors. However, in recognition of the continued commitment of its people to the success of the company, the Board has adopted a retention bonus plan for 2009. Anesiva,
Inc. (the “Company”) is pleased to offer you an initial bonus payment in the amount equal to Thirty-three Thousand Three Hundred Thirty-three Dollars ($33,333.00) to be earned and payable on March 1, 2009. Additional stay bonuses are
planned for May and June under similar terms subject to subsequent Board approval. 
 In the event that you voluntarily resign from
employment with the Company before May 1, 2009, you agree that you will repay to the Company this retention bonus amount paid to you pursuant to this letter. Any repayment under this paragraph must be repaid within thirty (30) days
following your last date of employment with the Company. In the event that you are involuntarily terminated from employment with the Company, you will not be liable for repayment of the retention bonus. 
 As a reminder, your employment with the Company continues to be “at will,” as described in your original Offer Letter. This retention bonus and
letter does not change any other terms of your Offer Letter. 
 We hope that you find the foregoing terms acceptable. Please indicate your
agreement with these terms by signing and dating below. 
  

	
	Sincerely,
	
	/s/ Michael L. Kranda
	 Michael L. Kranda
 President and Chief Executive
Officer

 I have read, accept and agree to, the terms of this agreement. 
  

					
	/s/ William C. Houghton	 		 	2/26/2009
	Name	 		 	Date

 HEADQUARTERS: 
 650 GATEWAY BOULEVARD, SOUTH SAN FRANCISCO, CA 94080 • PHONE (650) 624-9600 • FAX (650) 624-7540 
 WWW.ANESIVA.COMRetention Bonus Letter - John H. Tran

 Exhibit 10.85 
 

 
 Delivered in Person 
 February 25, 2009 
 John Tran 
 Dear John:

 As you know, given the macro economic climate and resulting impact on company operations, many corporations have scaled back and even
eliminated 2008 bonus programs as was the decision by Anesiva’s Board of Directors. However, in recognition of the continued commitment of its people to the success of the company, the Board has adopted a retention bonus plan for 2009. Anesiva,
Inc. (the “Company”) is pleased to offer you an initial bonus payment in the amount equal to Sixteen Thousand Dollars ($16,000.00) to be earned and payable on March 1, 2009. Additional stay bonuses are planned for May and June under
similar terms subject to subsequent Board approval. 
 In the event that you voluntarily resign from employment with the Company before
May 1, 2009, you agree that you will repay to the Company this retention bonus amount paid to you pursuant to this letter. Any repayment under this paragraph must be repaid within thirty (30) days following your last date of employment
with the Company. In the event that you are involuntarily terminated from employment with the Company, you will not be liable for repayment of the retention bonus. 
 As a reminder, your employment with the Company continues to be “at will,” as described in your original Offer Letter. This retention bonus and letter does not change any other terms of your Offer Letter.

 We hope that you find the foregoing terms acceptable. Please indicate your agreement with these terms by signing and dating below.

  

	
	Sincerely,
	
	/s/ Michael L. Kranda
	 Michael L. Kranda
 President and Chief Executive
Officer

 I have read, accept and agree to, the terms of this agreement. 
  

					
	/s/ John H. Tran	 		 	2/25/09
	Name	 		 	Date

 HEADQUARTERS: 
 650 GATEWAY BOULEVARD, SOUTH SAN FRANCISCO, CA 94080 • PHONE (650) 624-9600 • FAX (650) 624-7540 
 WWW.ANESIVA.COM

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