Document:

EX-10.1d

STOCK PLEDGE AGREEMENT

(Stock In _______________)

THIS STOCK PLEDGE AGREEMENT (“PLEDGE AGREEMENT”) is made to be effective as of this      day
of August, 2005, by MARTEK BIOSCIENCES CORPORATION, a Delaware corporation (“PLEDGOR”), for the
benefit of MANUFACTURERS AND TRADERS TRUST COMPANY, individually and in its capacity as the
Administrative Agent (“ADMINISTRATIVE AGENT”) for the “LENDERS” that are now or hereafter parties
to an Amended And Restated Loan And Security Agreement (as amended from time to time, the “LOAN
AGREEMENT”) dated to be effective as of September      , 2005, by and among the PLEDGOR, the AGENT,
BANK OF AMERICA, N.A., as Syndication Agent, and the LENDERS. Hereafter, the ADMINISTRATIVE AGENT
and the LENDERS are collectively referred to as the “SECURED PARTIES.”

RECITALS

The LENDERS have agreed to provide credit facilities (collectively, “LOANS”) to the PLEDGOR in
accordance with the terms of the LOAN AGREEMENT. The terms of the LOAN AGREEMENT require that the
PLEDGOR secure the LOANS inter alia with the pledge of the PLEDGOR’S stock ownership in
     . The PLEDGOR has executed and delivered this PLEDGE AGREEMENT in order to
satisfy such requirements.

NOW THEREFORE, for good and valuable consideration, the receipt and adequacy of which are
hereby acknowledged, the PLEDGOR agrees as follows:

Section 1. Definitions. As used in this PLEDGE AGREEMENT, the following
terms have the following meanings. Terms defined in this Section 1 or elsewhere in this PLEDGE
AGREEMENT are in all capital letters throughout this PLEDGE AGREEMENT. The singular use of any
defined term includes the plural and the plural use includes the singular.

Section 1.1. Account, Chattel Paper, Deposit Account, Document, General
Intangibles, Instrument, Investment Property, Letter-Of-Credit Right, And Payment Intangible.
The terms “ACCOUNT,” “CHATTEL PAPER,” “DEPOSIT ACCOUNT,” “DOCUMENT,” “GENERAL INTANGIBLES,”
“INSTRUMENT,” “INVESTMENT PROPERTY,” “LETTER-OF-CREDIT RIGHT,” and “PAYMENT INTANGIBLE” shall have
the same respective meanings as are given to those terms in the Uniform Commercial Code-Secured
Transactions, Title 9, Commercial Law Article, Annotated Code of Maryland, as amended
from time to time.

Section 1.2. Collateral. The term “COLLATERAL” collectively
means:(a) the PLEDGED STOCK and the proceeds, profits, and products of the PLEDGED STOCK;
(b) all dividends (cash and stock) and distributions of any kind made from time to time
with respect to the PLEDGED STOCK or which arise as a result of the ownership of the PLEDGED STOCK;
(c) all certificates representing the PLEDGED STOCK and certificates representing any
subsequent stock dividends or other distributions of stock paid or made in connection with the
PLEDGED STOCK; (d) all distributions of cash or stock made in connection with or arising
from any increase or reduction of capital, reclassification, merger, consolidation, stock split or
other transactions involving the CORPORATION or the PLEDGED STOCK; (e) all options,
warrants or rights of the PLEDGOR with respect to the CORPORATION and/or the PLEDGED STOCK, whether
as an addition to or in substitution or in exchange for the PLEDGED STOCK; (f) all
ACCOUNTS, CHATTEL PAPER, DEPOSIT ACCOUNTS, DOCUMENTS, GENERAL INTANGIBLES, INSTRUMENTS, INVESTMENT
PROPERTY, LETTER-OF-CREDIT RIGHTS, and PAYMENT INTANGIBLES of the PLEDGOR which arise out of or
relate in any respect to the PLEDGED STOCK or the ownership by the PLEDGOR of the PLEDGED STOCK;
(g) the products and proceeds of all of the foregoing; and (h) all RECORDS
relating or pertaining to any of the foregoing.

Section 1.3. Corporation. The term “CORPORATION” means      , a
     .

Section 1.4. Event Of Default. The term “EVENT OF DEFAULT” has the meaning
provided to such term in the LOAN AGREEMENT.

Section 1.5. Governmental Authority. The term “GOVERNMENTAL AUTHORITY”
means any nation or government, any state or other political subdivision thereof and any
municipality, court or other entity exercising executive, legislative, judicial, regulatory or
administrative functions of or pertaining to government.

Section 1.6. Laws. The term “LAWS” means all ordinances, statutes, rules,
regulations, orders, injunctions, writs or decrees of any GOVERNMENTAL AUTHORITY.

Section 1.7. Obligations. The term “OBLIGATIONS” shall have the same
meaning as given to that term in the LOAN AGREEMENT.

Section 1.8. Person. The term “PERSON” means any individual, corporation,
partnership, limited liability company, association, joint-stock company, trust, business trust,
unincorporated organization, joint venture, court, or GOVERNMENTAL AUTHORITY.

Section 1.9. Pledged Stock. The term “PLEDGED STOCK” means all shares of
stock of the CORPORATION owned by the PLEDGOR and all additional shares of stock in the CORPORATION
acquired by the PLEDGOR from time to time in any manner, together with all rights, options, and
issuances therefrom, including but not limited to      shares of the      stock of the
CORPORATION, as evidenced by Certificate Nos.      .

Section 1.10. Records. The term “RECORDS” means correspondence, memoranda,
tapes, discs, papers, books and other documents, or transcribed information of any type, whether
expressed in ordinary, computer or machine language.

Section 2. Pledge; Grant Of Security Interests And Liens. In order to
secure the payment and performance of the OBLIGATIONS when and as due, the PLEDGOR hereby assigns,
grants and pledges to the SECURED PARTIES a continuing first priority security interest, pledge and
lien in and to all of the COLLATERAL, whether now owned or hereafter acquired by the PLEDGOR,
together with all substitutions, replacements, renewals, products and proceeds thereof. Future
advances are secured. The PLEDGOR agrees to execute and deliver to the SECURED PARTIES such UCC-1
and other public filings as the SECURED PARTIES request to evidence in the public records the
pledge and granting of security interests and liens from the PLEDGOR to the SECURED PARTIES
provided for in this PLEDGE AGREEMENT.

Section 3. Delivery Of Certificates. The PLEDGOR shall deliver to the
ADMINISTRATIVE AGENT any certificates representing the PLEDGED STOCK, together with stock powers
duly executed by the PLEDGOR in accordance with the SECURED PARTIES’ instructions.

Section 4. Future Receipt Of Collateral. Except as expressly authorized to
the contrary by the terms of this PLEDGE AGREEMENT or as otherwise agreed to by the SECURED
PARTIES, the PLEDGOR shall accept as the agent and in trust for the SECURED PARTIES all COLLATERAL
received by the PLEDGOR after the date of this PLEDGE AGREEMENT, and shall promptly deliver all of
such COLLATERAL to the SECURED PARTIES.

Section 5. Voting Rights; Rights Incidental To Collateral. Unless an EVENT
OF DEFAULT has occurred and is continuing and the SECURED PARTIES shall have provided the written
election described below, the PLEDGOR shall retain all voting rights with respect to the PLEDGED
STOCK, not inconsistent with the terms of this PLEDGE AGREEMENT, and, for that purpose, the SECURED
PARTIES shall execute and deliver to the PLEDGOR any necessary proxies. Immediately upon the
occurrence and during the continuance of an EVENT OF DEFAULT and without regard as to whether the
PLEDGED STOCK has been registered in the names of the SECURED PARTIES or the nominee of the SECURED
PARTIES, the SECURED PARTIES shall have the right (but not the obligation) to make a written
election to exercise all voting rights as to the PLEDGED STOCK, together with all conversion,
exchange, subscription or other rights, privileges or options pertaining thereto as if the SECURED
PARTIES were the absolute owner thereof, including, without limitation, the right to exchange any
or all of the PLEDGED STOCK upon the merger, consolidation, reorganization, recapitalization or
other readjustment of the CORPORATION, or upon the exercise by the CORPORATION of any right,
privilege, or option pertaining to the PLEDGED STOCK, and, in connection therewith, to deliver any
of the PLEDGED STOCK to any committee, depository, transfer agent, registrar or other designated
agency upon such terms and conditions as the SECURED PARTIES may determine to be appropriate, all
without liability except to account for property actually received by the SECURED PARTIES or the
nominee of the SECURED PARTIES. The SECURED PARTIES shall have no duty to exercise any of the
aforesaid rights, privileges or options. The SECURED PARTIES shall not be deemed or construed to
have exercised any voting rights with respect to the PLEDGED STOCK unless and until the SECURED
PARTIES have made the above-described written election to exercise such voting rights.

Section 6. Cash Dividends And Cash Distributions. All cash dividends and
cash distributions made upon the PLEDGED STOCK shall be paid to the PLEDGOR until the occurrence of
an EVENT OF DEFAULT except to the extent otherwise prohibited by the terms and conditions of the
LOAN AGREEMENT or any other agreements between the PLEDGOR and/or the CORPORATION and the SECURED
PARTIES. During the continuance of any EVENT OF DEFAULT, all cash dividends and cash distributions
shall be paid to the SECURED PARTIES, and if any such dividends or distributions are paid to the
PLEDGOR, the PLEDGOR shall accept the same as the SECURED PARTIES’ agent, in trust for the SECURED
PARTIES, and shall deliver such dividends or distributions forthwith to the SECURED PARTIES in
exactly the form received with, as applicable, the PLEDGOR’S endorsement thereon. During the
continuance of any EVENT OF DEFAULT, all cash dividends, cash distributions, and other
distributions paid with respect to the PLEDGED STOCK shall be applied to the repayment of the
OBLIGATIONS, in such order of application as the SECURED PARTIES determine, regardless of when the
amounts due upon the OBLIGATIONS mature and are due and payable.

Section 7. Warranties And Representations. The PLEDGOR represents and
warrants to the SECURED PARTIES that:

Section 7.1. Authority. The PLEDGOR has, and has duly exercised, all
requisite power and authority to enter into this PLEDGE AGREEMENT, to pledge the PLEDGED STOCK for
the purposes described herein and to carry out the transactions contemplated by this PLEDGE
AGREEMENT.

Section 7.2. Ownership. The PLEDGOR is the sole registered, legal and
beneficial owner of one hundred percent (100%) of the issued and outstanding common stock of the
CORPORATION, calculated on a fully diluted basis.

Section 7.3. Status Of Pledged Stock. All of the shares of the PLEDGED
STOCK currently outstanding have been duly and validly issued, are fully paid and nonassessable,
and are owned by the PLEDGOR free of any pledge, mortgage, hypothecation, lien, charge, encumbrance
or security interest in such shares or the proceeds thereof, except for the security interests and
pledges granted herein and in the LOAN AGREEMENT.

Section 7.4. No Violation Of Restrictions. The execution and delivery of
this PLEDGE AGREEMENT by the PLEDGOR and the consent by the CORPORATION thereto, and the
performance of this PLEDGE AGREEMENT in accordance with its stated terms, will not violate or
constitute a default under the terms of any organizational documents of the CORPORATION, or any
agreement, restrictive shareholder’s agreement, indenture or other instrument, license, judgment,
decree, order, or LAWS applicable to or binding upon the PLEDGOR, the CORPORATION, the PLEDGED
STOCK, or any of the property of the PLEDGOR or the CORPORATION.

Section 7.5. Approvals. No approvals, consents, orders, authorizations, or
licenses are required from any PERSON or GOVERNMENTAL AUTHORITY for the execution and delivery by
the PLEDGOR of this AGREEMENT and the consummation of the transactions described herein.

Section 7.6. Restrictions. There are no restrictions upon the voting rights
or upon the transfer of any of the PLEDGED STOCK other than as physically appear upon the face of
the certificates evidencing the PLEDGED STOCK.

Section 7.7. Valid And Binding Obligation. This PLEDGE AGREEMENT is the
valid and binding obligation of the PLEDGOR, fully enforceable in accordance with all stated terms.

Section 7.8. Valid Pledge And Lien. The pledge of the COLLATERAL pursuant
to this PLEDGE AGREEMENT creates a valid and perfected first priority lien in the COLLATERAL
securing the payment and performance of the OBLIGATIONS.

Section 7.9. No Margin Stock. The PLEDGED STOCK is not “Margin Stock,” as
such term is defined in Regulation U of the Board of Governors of the Federal Reserve System (12
C.F.R. 221).

Section 8. No Duties Other Than Custodial Duties. The SECURED PARTIES shall
have no duty with respect to any of the COLLATERAL other than the duty to use reasonable care in
maintaining the safe physical custody of the certificates evidencing the PLEDGED STOCK.

Section 9. SECURED PARTIES Have No Obligation To Monitor Collateral. The
SECURED PARTIES shall have no duty or responsibility for collecting or receiving any amounts
payable on or with respect to the PLEDGED STOCK or any of the other COLLATERAL or for ascertaining,
monitoring, or enforcing any maturities, calls, conversions, exchanges, offers, tenders, or similar
matters relating to the PLEDGED STOCK or any of the other COLLATERAL or for informing the PLEDGOR
with respect to any of such matters. The SECURED PARTIES shall have no liability to the PLEDGOR
for any decline in the value of the PLEDGED STOCK which may occur while the COLLATERAL is subject
to the terms of this PLEDGE AGREEMENT. The PLEDGOR represents to the SECURED PARTIES that the
PLEDGOR has made its own arrangements for keeping informed of changes or potential changes
affecting the COLLATERAL, including, but not limited to, rights to convert, rights to subscribe,
payment of dividends, reorganization or other exchanges, tender offers and voting rights.

Section 10. Reporting Of Income. All income, dividends, earnings and
profits with respect to the COLLATERAL shall be reported for federal and state income tax purposes
as attributable to the PLEDGOR and not to the SECURED PARTIES. The CORPORATION and any other
PERSON authorized to report income distributions or earnings are authorized to issue any required
reports and forms indicating the PLEDGOR as the sole recipient of such distributions or earnings.

Section 11. No Obligation To Preserve Rights. The SECURED PARTIES shall be
under no obligation to take any steps to preserve rights or privileges in or to the COLLATERAL
against any PERSON.

Section 12. Covenants Of Pledgor. The PLEDGOR agrees that, until all of the
OBLIGATIONS have been paid, performed and satisfied in full, the PLEDGOR, in addition to the
covenants of the PLEDGOR set forth in the LOAN AGREEMENT, will comply with each of the following
covenants:

Section 12.1. No Transfers. The PLEDGOR will not sell, convey, or
otherwise dispose of any of the COLLATERAL or any interest therein, or create, incur, or permit to
exist any pledge, mortgage, lien, charge, encumbrance or any security interest whatsoever in or
with respect to any of the COLLATERAL or the proceeds thereof, except as may be expressly consented
to by the SECURED PARTIES in writing.

Section 12.2. Warrant Title. The PLEDGOR will, at the PLEDGOR’S sole
expense, warrant and defend the right, title, special property and security interests and pledges
of the SECURED PARTIES in and to the COLLATERAL against the claims of any PERSON, firm, the
CORPORATION, or other entity.

Section 12.3. No Additional Shares. The PLEDGOR will not consent to or
approve the issuance of any additional shares of any class of capital stock in the CORPORATION or
any securities convertible voluntarily by the holder thereof or automatically upon the occurrence
or non-occurrence of any event or condition into, or exchangeable for, any such shares; or any
warrants, options, rights, or other commitments entitling any person to purchase or otherwise
acquire any such shares.

Section 12.4. Delivery Of Notices Concerning Collateral. The PLEDGOR
agrees to promptly forward to the SECURED PARTIES, copies of any written notices or other
communications received by the PLEDGOR which relate or pertain to the COLLATERAL.

Section 12.5. Further Assurances. The PLEDGOR shall execute and deliver
from time to time such writings, and documents which, in the reasonable opinion of the SECURED
PARTIES or the SECURED PARTIES’ counsel, may be necessary to perfect, confirm, establish,
reestablish, continue, or complete the security interests, pledges and liens of the SECURED PARTIES
in the COLLATERAL, it being the intention of the PLEDGOR to provide hereby a full and absolute
warranty of further assurance to the SECURED PARTIES.

Section 12.6. Cooperation With Enforcement Activities. The PLEDGOR, upon
the occurrence of an EVENT OF DEFAULT and the written request therefor by the SECURED PARTIES, will
promptly execute and deliver to the SECURED PARTIES such documents, letters, or written
representations as may reasonably be requested by the SECURED PARTIES or any broker, from time to
time in order to accomplish the sale of all or any part of the COLLATERAL, including but not
limited to, all forms and documents required under any applicable LAWS.

Section 13. Waivers. No course of dealing between the PLEDGOR and the
SECURED PARTIES, nor any failure to exercise, nor any delay in exercising, any right, power or
privilege of the SECURED PARTIES hereunder or under any other agreement between the PLEDGOR and the
SECURED PARTIES, or under any agreement between the SECURED PARTIES and the CORPORATION, shall
operate as a waiver of any term or condition of this PLEDGE AGREEMENT; nor shall any single or
partial exercise of any right, power or privilege hereunder or thereunder preclude any other or
further exercise thereof or the exercise of any other right, power or privilege.

Section 14. Sale Of Collateral.

Section 14.1. Terms Of Sale. In addition to all other rights and remedies
available to the SECURED PARTIES pursuant to any other agreements with the PLEDGOR or as otherwise
provided by applicable LAWS, the SECURED PARTIES, may upon the occurrence of an EVENT OF DEFAULT
sell or otherwise dispose of and deliver all or any portion of the COLLATERAL, in one or more
parcels, at public or private sale or sales, at any exchange, broker’s board or at any location
selected by the SECURED PARTIES, at such prices and on such terms as the SECURED PARTIES may deem
best for cash or on credit, or for future delivery without assumption of any credit risk. Any such
sale shall be in compliance with all applicable LAWS. Any purchaser of the COLLATERAL, including
the SECURED PARTIES, shall purchase the COLLATERAL in whole or in part free of any right or equity
of redemption in the PLEDGOR, which right or equity is hereby expressly waived and released by the
PLEDGOR, to the extent permitted by applicable LAWS. The PLEDGOR acknowledges that the terms of
sale for the COLLATERAL may include: (a) a requirement that the COLLATERAL be sold to
only one individual purchaser for such purchaser’s own account and not as a representative of any
purchaser; (b) a requirement that any purchaser of all or any part of the COLLATERAL
represent in writing that such purchaser is purchasing the shares constituting the COLLATERAL for
investment purposes only and without any intention to make a distribution thereof; (c) a
requirement that the certificates for any PLEDGED STOCK bear a legend to the effect that the stock
may not be resold without compliance with applicable federal and state securities laws; and
(d) a requirement that any purchaser of the COLLATERAL make such representations and
warranties to the SECURED PARTIES as deemed necessary by the SECURED PARTIES.

Section 14.2. Delays In Sale; Private Sales. The PLEDGOR acknowledges that
it will be commercially reasonable for the SECURED PARTIES to:(a) defer disposing of all
or any portion of the COLLATERAL after an EVENT OF DEFAULT has occurred for as long as the
CORPORATION or the SECURED PARTIES may require to comply with any requirements of applicable LAWS,
notwithstanding the fact that the value of the COLLATERAL may decline during the time that
disposition is deferred; and (b) sell all or any part of the COLLATERAL at private sale,
subject to investment letter or in any other manner which will not require the COLLATERAL, or any
part thereof, to be registered in accordance with the Securities Act of 1933, as amended,
or the rules and regulations promulgated thereunder, or any other applicable LAW. The PLEDGOR
acknowledges that the SECURED PARTIES may, in the SECURED PARTIES’ sole and absolute discretion,
approach a restricted number of potential purchasers and that a sale under such circumstances may
yield a lower price for the COLLATERAL or any portions thereof than would otherwise be obtainable
if the COLLATERAL were registered and sold in the open market. The PLEDGOR acknowledges that a
private sale of the COLLATERAL would be a commercially reasonable sale.

Section 14.3. Application Of Proceeds Of Disposition. The proceeds from any
sale or from any other disposition of the COLLATERAL shall be applied as follows:

a. First, to the costs and expenses incurred in connection with the sale or
disposition of the COLLATERAL, including but not limited to all costs incurred in the care or
safekeeping of the COLLATERAL, reasonable attorneys’ fees, broker’s commissions, appraiser’s fees
and other expenses incurred by the SECURED PARTIES;

b. Second, to the satisfaction of the OBLIGATIONS regardless of when the amounts due
upon the OBLIGATIONS mature and are due and payable;

c. Third, to the payment of any other amounts or to such other application as required
by applicable LAWS or as required by the decree, directive or injunction issued by a GOVERNMENTAL
AUTHORITY; and

d. Fourth, to the PLEDGOR to the extent of any surplus proceeds.

Section 14.4. Notice; Procedures Of Sale. The SECURED PARTIES need not give
more than ten (10) business days notice of the time and place of any public sale or of the time
after which a private sale of any or all of the COLLATERAL may take place, which notice the PLEDGOR
hereby agrees to be commercially reasonable. The SECURED PARTIES shall be entitled to purchase any
or all of the COLLATERAL in any sale in the name or names of the SECURED PARTIES, or in the name of
any designee or nominee of the SECURED PARTIES. In connection with any sale or transfer of any or
all of the COLLATERAL, the nominee of the SECURED PARTIES shall have the right to execute any
document or form, in the name of the SECURED PARTIES or in the name of the PLEDGOR, which may be
necessary or desirable in order to implement such sale, including without limitation any forms
required pursuant to Rule 144 promulgated by the Securities And Exchange Commission. The
PLEDGOR hereby agrees to cooperate fully with the SECURED PARTIES in order to permit the SECURED
PARTIES to sell, at foreclosure or other private sale, any or all of the COLLATERAL in compliance
with all applicable LAWS.

Section 15. Remedies And Rights Cumulative. The rights and remedies
provided in this PLEDGE AGREEMENT and in the LOAN AGREEMENT or otherwise provided by any other
agreement between the PLEDGOR and the SECURED PARTIES shall be cumulative, and the exercise of any
particular right or remedy shall not preclude the exercise of any other rights or remedies.

Section 16. Invalidity Of Any Part. If any provision or part of any
provision of this PLEDGE AGREEMENT shall for any reason be held invalid, illegal, or unenforceable
in any respect, such invalidity, illegality, or unenforceability shall not affect any other
provisions or the remaining part of any effective provisions of this PLEDGE AGREEMENT, and this
PLEDGE AGREEMENT shall be construed as if such invalid, illegal, or unenforceable provision or part
thereof had never been contained herein, but only to the extent of its invalidity, illegality, or
unenforceability.

Section 17. Amendment Or Waiver. This PLEDGE AGREEMENT may be amended only
by a writing duly executed by the PLEDGOR and by the ADMINISTRATIVE AGENT with the consent of those
other SECURED PARTIES as may be required under the LOAN AGREEMENT. No waiver by the SECURED
PARTIES of any of the provisions of this PLEDGE AGREEMENT or of any of the rights or remedies of
the SECURED PARTIES with respect hereto shall be considered effective or enforceable unless in
writing.

Section 18. Fees And Expenses; Indemnification. The PLEDGOR shall pay all
fees, expenses, costs and charges, including reasonable attorney’s fees, which may be incurred by
the SECURED PARTIES in connection with enforcing any term or provision of this PLEDGE AGREEMENT.
The PLEDGOR shall indemnify and hold the SECURED PARTIES harmless from and against, and reimburse
the SECURED PARTIES with respect to, any and all loss, damage, liability, cost or expense
(including reasonable attorneys’ fees) incurred by the SECURED PARTIES from time to time which in
any manner relate or pertain to this PLEDGE AGREEMENT and the actions and transactions contemplated
herein. The foregoing indemnification obligation shall include, but is not limited to,
indemnification of the SECURED PARTIES with respect to all claims brought against the SECURED
PARTIES based upon allegations that any prospectus, memorandum or other disclosure document
furnished to the purchaser of any of the COLLATERAL contains any untrue or allegedly untrue
statement of a material fact which statement is derived from statements or representations made by
the PLEDGOR.

Section 19. Notices. Any notice required or permitted by or in connection
with this AGREEMENT shall be in writing and shall be made by facsimile (confirmed on the date the
facsimile is sent by one of the other methods of giving notice provided for in this Section) or by
hand delivery, by Federal Express, or other similar overnight delivery service, or by certified
mail, unrestricted delivery, return receipt requested, postage prepaid, addressed to the SECURED
PARTIES or the PLEDGOR at the appropriate address set forth below or to such other address as may
be hereafter specified by written notice by the SECURED PARTIES or the PLEDGOR. Notice shall be
considered given as of the date of the facsimile or the hand delivery, one (1) calendar day after
delivery to Federal Express or similar overnight delivery service, or three (3) calendar days after
the date of mailing, independent of the date of actual delivery or whether delivery is ever in fact
made, as the case may be, provided the giver of notice can establish the fact that notice was given
as provided herein. If notice is tendered pursuant to the provisions of this Section and is
refused by the intended recipient thereof, the notice, nevertheless, shall be considered to have
been given and shall be effective as of the date herein provided.

MANUFACTURERS AND TRADERS TRUST COMPANY,

As Administrative Agent

25 S. Charles Street, 12th Floor

Baltimore, Maryland 21201

Attn: Hugh E. Giorgio, Vice President

Facsimile: (410) 244-4447

If to the PLEDGOR:

MARTEK BIOSCIENCES CORPORATION

6480 Dobbin Road

Columbia, Maryland 21045

Attn.: George P. Barker, Esquire

Fax No.: (410) 740-2985

With A Courtesy Copy To:

HOGAN & HARTSON, L.L.P.

111 South Calvert Street, Suite 1600

Baltimore, Maryland 21202

Attn.: Kevin G. Gralley, Esquire

Fax No.: (410) 539-6981

The failure of the SECURED PARTIES to send the above courtesy copy shall not impair the
effectiveness of notice given to the PLEDGOR in the manner provided herein.

Section 20. Binding Effect. This PLEDGE AGREEMENT shall inure to the
benefit of and shall be binding upon the respective successors and assigns of the parties hereto.

Section 21. Choice Of Law. The laws of the State of Maryland (excluding,
however, conflict of law principles) shall govern and be applied to determine all issues relating
to this PLEDGE AGREEMENT and the rights and obligations of the parties hereto, including the
validity, construction, interpretation, and enforceability of this PLEDGE AGREEMENT and its various
provisions and the consequences and legal effect of all transactions and events which resulted in
the execution of this PLEDGE AGREEMENT or which occurred or were to occur as a direct or indirect
result of this PLEDGE AGREEMENT having been executed.

Section 22. Consent To Jurisdiction; Agreement As To Venue. The PLEDGOR
irrevocably consents to the non-exclusive jurisdiction of the courts of the State of Maryland and,
if a basis for federal jurisdiction exists, of the United States District Court For The District Of
Maryland. The PLEDGOR agrees that venue shall be proper in any circuit court of the State of
Maryland selected by the SECURED PARTIES or in the United States District Court For The District Of
Maryland if a basis for federal jurisdiction exists and waives any right to object to the
maintenance of a suit in any of the state or federal courts of the State of Maryland on the basis
of improper venue or of inconvenience of forum.

Section 23. Photocopies Sufficient. The PLEDGOR agrees that the SECURED
PARTIES may record photographic or carbon copies of this PLEDGE AGREEMENT or any financing
statement executed by the PLEDGOR in connection with this transaction, and that such copies shall
be as fully effective and valid as original documents.

Section 24. Number, Gender And Captions. As used herein, the singular shall
include the plural and the plural may refer to only the singular. The use of any gender shall be
applicable to all genders. The captions contained herein are for purposes of convenience only and
are not a part of this PLEDGE AGREEMENT.

Section 25. Final Agreement. This PLEDGE AGREEMENT contains the final and
entire understanding of the parties relating to the pledge and assignment of the PLEDGED STOCK and
any terms and conditions not set forth in this PLEDGE AGREEMENT relating to the pledge and
assignment of the PLEDGED STOCK are not a part of this PLEDGE AGREEMENT and the understandings of
the parties.

Section 26. Actions Against Secured Parties. Any action brought by the
PLEDGOR against the SECURED PARTIES which is based, directly or indirectly, upon this PLEDGE
AGREEMENT or any matter related to this PLEDGE AGREEMENT or any action taken by the SECURED PARTIES
in enforcing or construing this PLEDGE AGREEMENT shall be brought only in the courts of the State
of Maryland. The PLEDGOR agrees that any forum other than the State of Maryland is an inconvenient
forum and that a suit brought by the PLEDGOR against the SECURED PARTIES in a court of any state
other than the State of Maryland should be forthwith dismissed or transferred to a court located in
the State of Maryland by that court.

Section 27. Waiver Of Trial By Jury. The PLEDGOR and the SECURED PARTIES,
by their execution and acceptance, respectively, of this PLEDGE AGREEMENT, agree that any suit,
action, or proceeding, whether claim or counterclaim, brought or instituted by any party hereto or
any successor or assign of any party on or with respect to this PLEDGE AGREEMENT or which in any
way relates, directly or indirectly, to this PLEDGE AGREEMENT or any event, transaction, or
occurrence arising out of or in any way connected with this PLEDGE AGREEMENT, or the dealings of
the parties with respect thereto, shall be tried only by a court and not by a jury. EACH PARTY
HEREBY EXPRESSLY WAIVES ANY RIGHT TO A TRIAL BY JURY IN ANY SUCH SUIT, ACTION, OR PROCEEDING.

IN WITNESS WHEREOF, the parties have duly executed this PLEDGE AGREEMENT under seal as of the
date first above written.

	 	 	 	 	 	 	 
	WITNESS/ATTEST:

	 	THE PLEDGOR:
	 	

	 	

	 
	 	 	 	 	 	 
	 	 	MARTEK BIOSCIENCES CORPORATION,
	 	 
	 
	 	 	 	 	 	 
	
 
	 	A Delaware Corporation
	 	

	 	

	 
	 	 	 	 	 	 
	
 
	 	By:
	 	 	 	(SEAL)
	 

	 	 	 	 
	 	

	
 
	 	 	 	Name:
	 	

	
 
	 	 	 	 
	 	 
	
 
	 	 	 	Title:
	 	

	
 
	 	 	 	 
	 	 
	 
	 	 	 	 	 	 

1

ACKNOWLEDGMENT AND AGREEMENT OF CORPORATION

MARTEK      , a Delaware corporation (“CORPORATION”) acknowledges this      day of
     , 200     , the receipt of an executed copy of the Stock Pledge Agreement (“PLEDGE
AGREEMENT”) annexed hereto from MARTEK BIOSCIENCES CORPORATION (“PLEDGOR”), for the benefit of
MANUFACTURERS AND TRADERS TRUST COMPANY, individually and in its capacity as the Administrative
Agent (“ADMINISTRATIVE AGENT”) for the “LENDERS” that are now or hereafter parties to an Amended
And Restated Loan And Security Agreement (as amended from time to time, the “LOAN AGREEMENT”) dated
to be effective as of September      , 2006, by and among the PLEDGOR, the ADMINISTRATIVE AGENT, and
the LENDERS (hereafter, the ADMINISTRATIVE AGENT and the LENDERS are collectively referred to as
the “SECURED PARTIES”). The CORPORATION agrees to evidence such receipt and acknowledgment, and
the pledges and security interests granted to the SECURED PARTIES therein, upon the stock registry
and books and records of the CORPORATION. The CORPORATION consents to each of the pledges, grants
of security interests, liens and covenants and agreements of the PLEDGOR set forth in the PLEDGE
AGREEMENT. The CORPORATION agrees that the CORPORATION will not make any payments or take any
actions which would cause the PLEDGOR to be in violation of the terms of the PLEDGE AGREEMENT, or
which would otherwise not be in compliance with the PLEDGE AGREEMENT. The CORPORATION agrees to
pay to the SECURED PARTIES upon the written request of the SECURED PARTIES all cash dividends and
other distributions which in the absence of the SECURED PARTIES’ request would otherwise be payable
to the PLEDGOR.

	 	 	 	 	 	 	 	 	 
	WITNESS/ATTEST:	 	MARTEK ____________________,

	 
	 	A Delaware Corporation
	 	 	 	 
	 
	 	By:
	 	(SEAL)

	 
	 	 	 	 	 	 	 	 
	 
	 	 	 	 	 	Name:  _____________________________

	 
	 	 	 	 	 	Title:    _____________________________

	 
	 	Date:
	 	August ___, 2005

2EX-10.1e

ASSIGNMENT AND ACCEPTANCE

[Date]

Reference is made to the Amended And Restated Loan And Security Agreement dated to be
effective as of September      , 2005 (as amended or supplemented from time to time, the ALOAN
AGREEMENT”), by and among MARTEK BIOSCIENCES CORPORATION, a Delaware corporation (“BORROWER”), and
MANUFACTURERS AND TRADERS TRUST COMPANY, as ADMINISTRATIVE AGENT, and the LENDERS party thereto.
Capitalized terms which are defined in the LOAN AGREEMENT and which are used herein without
definition shall have the same meanings herein as in the LOAN AGREEMENT.

     (“ASSIGNOR”) and
     (“ASSIGNEE”) agree as follows:

1. The ASSIGNOR hereby sells and assigns to the ASSIGNEE, and the ASSIGNEE hereby purchases
and assumes from the ASSIGNOR, as of the EFFECTIVE DATE (as defined below), a      % interest (the
“ASSIGNED INTEREST”) in and to the LOAN (“LOAN”) which is held by the ASSIGNOR and in and to all of
the ASSIGNOR=S interests, rights and obligations under the LOAN AGREEMENT and other CREDIT
DOCUMENTS with respect to the LOAN and the ASSIGNOR thereby retains      % of its interest therein
(the “RETAINED INTEREST”) in the LOAN. This Assignment And Acceptance is intended to be a “LENDER
ASSIGNMENT.”

2. The ASSIGNOR: (a) represents that, as of the date hereof, (i) its COMMITMENT PERCENTAGE for
the LOAN (without giving effect to assignments thereof which have not yet become effective) under
the LOAN AGREEMENT and (ii) the outstanding unpaid principal balance of the LOAN (unreduced by any
assignments thereof which have not yet become effective) under the LOAN AGREEMENT are each set
forth in Section 2 of Schedule I hereto; (b) makes no representation or warranty and assumes no
responsibility with respect to any statements, warranties or representations made in or in
connection with the LOAN AGREEMENT or any other CREDIT DOCUMENT or the execution, legality,
validity, enforceability, genuineness, sufficiency or value of the LOAN AGREEMENT or of the other
CREDIT DOCUMENTS or any other instrument or document furnished pursuant thereto, other than that
the ASSIGNOR is the legal and beneficial owner of the interest being assigned by it hereunder and
that such interest is free and clear of any adverse claim; (c) makes no representation or warranty
and assumes no responsibility with respect to the financial condition of the BORROWER or the
performance or observance by the BORROWER of any of the OBLIGATIONS; and (d) attaches the NOTE
presently held by the ASSIGNOR and requests that the ADMINISTRATIVE AGENT and the BORROWER arrange
for the exchange of such NOTE for replacement NOTES payable to each of the ASSIGNOR and the
ASSIGNEE in accordance with the procedures set forth in the LOAN AGREEMENT, in the following
amounts:

	 	 	 	 	 
	Promissory Note	 	 
	Payable To The Order Of	 	Principal Amount Of Note
	ASSIGNOR
	 	$	 	 
	 
	 	 	 	 
	ASSIGNEE
	 	$	 	 
	 
	 	 	 	 

3. The ASSIGNEE: (a) represents and warrants that it is legally authorized to enter into this
Assignment And Acceptance; (b) confirms that it has received a copy of the LOAN AGREEMENT, together
with copies of the most recent financial statements delivered pursuant to the requirements of the
LOAN AGREEMENT and such other documents and information as it has deemed appropriate to make its
own credit analysis and decision to enter into this Assignment And Acceptance; (c) agrees that it
will, independently and without reliance upon the ASSIGNOR or any other LENDER or the
ADMINISTRATIVE AGENT and based on such documents and information as it shall deem appropriate at
the time, continue to make its own credit decisions in taking or not taking action in connection
with the LOAN or any of the CREDIT DOCUMENTS; (d) confirms that it is an ELIGIBLE ASSIGNEE; (e)
appoints and authorizes the ADMINISTRATIVE AGENT to take such action as ADMINISTRATIVE AGENT on its
behalf and to exercise such powers pursuant to the CREDIT DOCUMENTS as are delegated to the
ADMINISTRATIVE AGENT by the terms thereof, together with such powers as are reasonably incidental
thereto; (f) agrees that it will perform all the obligations which by the terms of the LOAN
AGREEMENT and the other CREDIT DOCUMENTS are required to be performed by it as a LENDER; and (g)
agrees that it will keep confidential all non-public information with respect to the BORROWER
obtained pursuant to the CREDIT DOCUMENTS in accordance with the provisions of the LOAN AGREEMENT.

4. The effective date for this Assignment and Acceptance shall be as set forth in Section 1 of
Schedule I hereto (the “EFFECTIVE DATE”). Following the execution of this Assignment And
Acceptance, it will be delivered to the ADMINISTRATIVE AGENT for consent thereby and acceptance and
recording in the REGISTER.

5. Upon such consents, acceptance and recording from and after the EFFECTIVE DATE, (i) the
ASSIGNEE shall be deemed to be a party to the LOAN AGREEMENT and the other CREDIT DOCUMENTS to
which LENDERS are parties and to the extent provided in this Assignment And Acceptance, have the
rights and obligations of a LENDER, and (ii) the ASSIGNOR shall, to the extent provided in this
Assignment And Acceptance and the LOAN AGREEMENT, relinquish its rights and be released from its
obligations under the LOAN AGREEMENT and the other CREDIT DOCUMENTS.

6. Upon such consents, acceptance and recording, from and after the EFFECTIVE DATE, the
ADMINISTRATIVE AGENT shall forward all payments in respect of the interests assigned hereby
(including payments of principal, interest, fees and other amounts) directly to the ASSIGNEE. The
ASSIGNOR and ASSIGNEE shall make all appropriate adjustments in payments for periods prior to the
EFFECTIVE DATE or with respect to the making of this assignment directly between themselves.

7. THIS ASSIGNMENT AND ACCEPTANCE SHALL BE DEEMED TO BE A CONTRACT UNDER SEAL AND SHALL BE
GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF MARYLAND, WITHOUT REGARD TO
CONFLICT OF LAW PRINCIPLES.

ASSIGNOR:

     

	 	 	 	 	 	 	 	 	 	 	 	 	 
	      By:

	 	—(SEAL)
	         Name:  _________________

	         Title: _________________

	Commitment Percentage:
	 	 	—	%	 	 	 	 	 	 	 	 
	Commitment Amount:
	 	$	—	 	 	 	 	 	 	 	 	 

ASSIGNEE:

     

	 	 	 	 	 	 	 	 	 
	   By:

	 	—(SEAL)
	      Name:  _________________

	      Title: _________________

	Commitment Percentage:
	 	 	—	%	 	 	 	 
	Commitment Amount:
	 	$	—	 	 	 	 	 

1

Consented to and Accepted:

ADMINISTRATIVE AGENT:

MANUFACTURERS AND TRADERS TRUST COMPANY

By:      (SEAL)

Name:      

Title:      

BORROWER:

MARTEK BIOSCIENCES CORPORATION

By:      (SEAL)

Name:      

Title:      

Schedule I

to

Assignment And Acceptance

1. Effective Date      

2. Assignor’s Interest Prior to Assignment

(a) Commitment Percentage

of Assignor      %

(b) Commitment Amount

of Assignor $     

3. Assigned Interest (from paragraph 1

of Assignment And Acceptance)      %

4. Assignee’s Extensions of Credit After Effective Date

(a) Commitment Percentage      %

Acquired by Assignee

(b) Commitment Amount Acquired By Assignee

(line 2(b) multiplied by line 3) $     

5. Retained Interest of Assignor after Effective Date

(a) Commitment Percentage

	 	 	 
	Retained by Assignor (from Paragraph 1

of Assignment And Acceptance)

	 	

     %

(d) Commitment Amount Retained by Assignor

(line 2(b) multiplied by line 5(a)) $     

2

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