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                                                                    EXHIBIT 10.1

                               SECOND AMENDMENT TO

                                 ALLERGAN, INC.

                      EXECUTIVE DEFERRED COMPENSATION PLAN
                                 (RESTATED 2000)

The ALLERGAN, INC. EXECUTIVE DEFERRED COMPENSATION PLAN (the "Plan") is hereby
amended to read as follows:

I. Section 5.1 of the Plan, entitled Deferral Accounts, is hereby amended by
deleting the following language "(i) the Committee shall make the Plan
Restoration Credit contingent on vesting in such amounts under the Savings and
Investment Plan and the Employee Stock Ownership Plan, and (ii)".

II. Section 5.3 of the Plan is hereby amended by deleting subsection (a), adding
new subsections (a) and (b) to read as follows, and by redesignating existing
subsections (b) and (c) sequentially as subsections (c) and (d):

          5.3 Participant Investment Elections.

          (a) Deferrals On and After January 1, 2002. Any Deferral Election made
     by a Participant with respect to a Deferral Period beginning on or after
     January 1, 2002 shall be credited with investment earnings at the Fund Rate
     and shall not be eligible to be credited with interest at the Company Rate.

          (b) Deferrals On and After January 1, 2000 and prior to January 1,
     2002. Except as otherwise provided in the next sentence herein, any
     Deferral Election made by a Participant on or after January 1, 2000 shall
     be credited with investment earnings at the Fund Rate and shall not be
     eligible to be credited with interest at the Company Rate. Notwithstanding
     the preceding sentence, any Eligible Employee who was a Participant as of
     November 1, 1999 and who, prior to January 1, 2000, had attained the age of
     fifty-five (55) and had completed at least five (5) years of Credited
     Service shall be entitled to elect the investment of all or any portion of
     any Deferral Election made by such Participant on or after January 1, 2000
     and for Deferral Periods beginning prior to January 1, 2002 at the Company
     Rate or the Fund Rate.

III. Section 6.3 of the Plan is hereby amended in its entirety to read as
follows:

          6.3 Time of Commencement. A Participant may elect in the Participation
     Agreement to have payments begin within sixty (60) days following, the date
     of Termination of Employment or, alternatively, (a), on the first business
     day of January of the next following calendar year or (b) on the first
     business day of January of a later year (not to exceed ten (10) years from
     the date of Termination

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     of Employment or, if earlier, the year in which the Participant attains age
     seventy (70)). Payments that are scheduled to be made on the first business
     day in January may be delayed (but not more than thirty (30) days) in order
     to complete any necessary valuation or accounting with respect to the
     Deferral Account of the Participant.

IV. Section 7.2 of the Plan is hereby amended in its entirety to read as
follows:

          7.2 Form of Termination Benefits. The termination benefit shall be
     paid in a single lump sum payment within sixty (60) days following the date
     of Termination of Employment or, if otherwise elected in the Participation
     Agreement, either (a) on the first business day of January following
     Termination of Employment or (b) if at least five (5) years of Credited
     Service has elapsed, in five (5) annual installments. If installments are
     to be paid under this Section 7.2, they shall commence within sixty (60)
     days following the date of Termination of Employment. Payments that are
     scheduled to be made hereunder may be delayed (but not more than thirty
     (30) days) in order to complete any necessary valuation or accounting with
     respect to the Deferral Account of the Participant. If (a) above is elected
     by the Participant, to the extent that the Company Rate applies, the only
     interest to be credited after the date of Termination of Employment shall
     be at eighty percent (80%) of the Company Rate (however a Participant who
     is eligible to elect (b) above shall be credited with interest at the
     Company Rate, to the extent that the Company Rate applies, regardless of
     whether he or she elects distribution under (a) or (b)). Notwithstanding
     the foregoing, the Company may, in its sole discretion (except following a
     Change in Control as defined in Section 14.2), elect to revise the payment
     of a single lump sum and instead to pay the termination benefits over a
     period of three (3) years in annual installments.

V. Section 8.1 of the Plan, entitled Death of Employee Prior to Retirement Date,
is hereby amended by changing the phrase "less than fifty thousand dollars
($50,000)" to "fifty thousand dollars ($50,000) or less" and by changing the
phrase "fifty thousand dollars ($50,000) or more" to "more than fifty thousand
dollars ($50,000)" as those phrases appear in the first sentence of such
Section.

VI. Section 8.5 of the Plan is hereby amended in its entirety to read as
follows:

          8.5 Special Death Benefits. There shall be a Special Death Benefit
     payable from the Trust to Allergan, Inc. if a Participant dies prior to
     termination of employment and such Participant is a Corporate Officer of
     Allergan, Inc. on the date of his or her death. The term "Corporate
     Officer" means the Corporation's President, Chief Executive Officer and
     each of the Corporation's Corporate Vice Presidents (excluding any
     individual who is not named as an insured person under a life insurance
     contract owned by the Trust pursuant to Section 15.3). The Corporation's
     Board of Directors may change the definition of Corporate Officer by Board
     resolution. The Special Death Benefit shall be One Million Five Hundred
     Thousand Dollars ($1,500,000), unless such amount is adjusted by the Board.
     Entitlement to the Special Death Benefit shall be

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     conditioned on such life insurance being in effect on the date of death and
     to the extent the amount is sufficient to cover the Special Death Benefit.
     The Special Death Benefit payable to the Beneficiary of a Participant of a
     Corporate Officer shall no longer apply beginning on July 1, 2001.

VII. Appendix A to the Plan, entitled Fund Media, is amended by changing the
Fund entitled "Bankers Trust EAFE Equity Fund Index" to "Deutsche VIT EAFE
Equity Index" and by adding a sentence at the end of Appendix A to read as
follows:

     This Appendix A shall be changed automatically to reflect the current Fund
     Media when the Committee adds or deletes Fund Media in accordance with
     Section 5.4 of the Plan.

VIII. This Second Amendment shall be effective as of July 1, 2001, except that
the amendment to Section 5.1 shall be effective as of January 1, 2000, the date
of restatement of the Plan.

     IN WITNESS WHEREOF, Allergan, Inc. hereby executes this Amendment on the
31st day of July, 2001.

ALLERGAN, INC.

BY: /s/ Aimee S. Weisner
    -----------------------------------------
        Aimee S. Weisner, Assistant Secretary

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                                                                    EXHIBIT 10.1

                               CORIXA CORPORATION

                       2001 EMPLOYEE STOCK PURCHASE PLAN
                            (EFFECTIVE JUNE 1, 2001)

     The following amends and restates the 1997 Employee Stock Purchase Plan of
Corixa Corporation, and constitutes the provisions of the 2001 Employee Stock
Purchase Plan of Corixa Corporation, effective June 1, 2001.

     1. Purpose. The purpose of the Plan is to provide Employees of the Company
and its Designated Subsidiaries with an opportunity to purchase Common Stock of
the Company through accumulated payroll deductions. It is the intention of the
Company to have the Plan qualify as an "Employee Stock Purchase Plan" under
Section 423 of the Internal Revenue Code of 1986, as amended. The provisions of
the Plan, accordingly, shall be construed so as to extend and limit
participation in a manner consistent with the requirements of that section of
the Code.

     2. Definitions.

     (a) "Board" shall mean the Board of Directors of the Company or a Committee
appointed by the Board pursuant to Section 13.

     (b) "Code" shall mean the Internal Revenue Code of 1986, as amended.

     (c) "Common Stock" shall mean the common stock of the Company.

     (d) "Company" shall mean Corixa Corporation, a Delaware corporation.

     (e) "Compensation" shall mean all base straight time gross earnings,
including bonuses, but excluding payments for overtime, shift premiums and
commissions, awards, and other compensation.

     (f) "Designated Subsidiaries" shall mean the Subsidiaries that have been
designated by the Board from time to time in its sole discretion as eligible to
participate in the Plan.

     (g) "Employee" shall mean any individual who is a regular employee of the
Company or a Designated Subsidiary for purposes of tax-withholding under the
Code. For purposes of the Plan, the employment relationship shall be treated as
continuing intact while the individual is on sick leave or other leave of
absence approved by the Company. Where the period of leave exceeds 90 days and
the individual's right to reemployment is not guaranteed either by statute or by
contract, the employment relationship will be deemed to have terminated on the
91st day of such leave.

     (h) "Enrollment Date" shall mean the first Trading Day of each Offering
Period.

     (i) "Enrollment Date Price" shall mean the Fair Market Value of a share of
Common Stock on the last Trading Day prior to the Enrollment Date.

     (j) "Exercise Date" shall mean the last Trading Day of each Purchase
Period.

     (k) "Fair Market Value" shall mean, as of any date, the value of Common
Stock determined as follows:

          (1) If the Common Stock is listed on any established stock exchange or
     a national market system, including without limitation the National Market
     System of the National Association of Securities Dealers, Inc. Automated
     Quotation ("NASDAQ") System, its Fair Market Value shall be the closing
     sales price for such stock (or the closing bid, if no sales were reported),
     as quoted on such exchange (or the exchange with the greatest volume of
     trading in Common Stock) or system on the day of such determination, as
     reported in The Wall Street Journal or such other source as the Board deems
     reliable, or;

          (2) If the Common Stock is quoted on the NASDAQ system (but not on the
     National Market System thereof) or is regularly quoted by a recognized
     securities dealer but selling prices are not reported, its Fair Market
     Value shall be the mean between the high and low asked prices for the
     Common Stock on

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     the day of such determination, as reported in The Wall Street Journal or
     such other source as the Board deems reliable, or;

          (3) In the absence of an established market for the Common Stock, the
     Fair Market Value thereof shall be determined in good faith by the Board.

     (l) "Offering Period" shall mean, subject to the discretion of the Board
pursuant to Section 4, a period of approximately twenty-four (24) months,
commencing on the first Trading Day on or after each January 1, April 1, July 1
or October 1 and terminating on the last Trading Day in December, March, June or
September, whichever is twenty-four (24) months following the commencement date
of the Offering Period.

     (m) "Plan" shall mean this 2001 Employee Stock Purchase Plan.

     (n) "Participant" shall mean an Employee who is participating in the Plan.

     (o) "Purchase Period" shall mean the approximately three-month period
commencing after one Exercise Date and ending with the next following Exercise
Date, except that the first Purchase Period of any Offering Period shall
commence on the Enrollment Date and end with the next following Exercise Date.

     (p) "Purchase Price" shall mean an amount equal to a designated percentage
of the Enrollment Date Price or a designated percentage of the Fair Market Value
on the Exercise Date, whichever is lower. Each designated percentage shall be
85% unless determined otherwise by the Board with respect to any Offering
Period, but shall in no event be less than 85%.

     (q) "Reserves" shall mean the number of shares of Common Stock covered by
each purchase right under the Plan which have not yet been exercised and the
number of shares of Common Stock which have been authorized for issuance under
the Plan but not yet placed under purchase right.

     (r) "Subsidiary" shall mean a corporation, domestic or foreign, of which
not less than 50% of the voting shares are held by the Company or a Subsidiary,
whether or not such corporation now exists or is hereafter organized or acquired
by the Company or a Subsidiary.

     (s) "Trading Day" shall mean a day on which national stock exchanges and
the National Association of Securities Dealers Automated Quotation (NASDAQ)
System are open for trading.

     3. Eligibility.

     (a) Any Employee, as defined in Section 2(g), who shall be employed by the
Company or a Designated Subsidiary on a given Enrollment Date shall be eligible
to participate in the Plan except that an Employee shall not be eligible to
participate in the Plan unless, on the Enrollment Date, such Employee has been
in the employ of the Company or the Designated Subsidiary, as the case may be,
for such continuous period preceding such grant as the Board may require, but in
no event shall the required period of continuous employment be equal to or
greater than two (2) years. In addition, unless otherwise determined by the
Board and set forth in the terms of the applicable offering, no Employee shall
be eligible to participate in the Plan, unless, on the Enrollment Date, such
Employee's customary employment with the Company or the Designated Subsidiary is
for at least twenty (20) hours per week and at least five (5) months per
calendar year.

     (b) Any provisions of the Plan to the contrary notwithstanding, no Employee
shall be granted a purchase right under the Plan(i) if, immediately after the
grant, such Employee (or any other person whose stock would be attributed to
such Employee pursuant to Section 424(d) of the Code) would own stock and/or
hold outstanding purchase rights to purchase stock possessing five percent (5%)
or more of the total combined voting power or value of all classes of stock of
the Company or of any Subsidiary of the Company, or (ii) which permits his or
her rights to purchase stock under all employee stock purchase plans of the
Company and its Subsidiaries to accrue at a rate which exceeds Twenty-Five
Thousand Dollars ($25,000) worth of stock (determined at the fair market value
of the shares at the time such purchase right is granted) for each calendar year
in which such purchase right is outstanding at any time.

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     4. Offering Periods. The Plan shall be implemented by consecutive and
overlapping Offering Periods. The Board shall have the power to change the
duration of Offering Periods with respect to future offerings without
shareholder approval if such change is announced at least fifteen (15) days
prior to the scheduled beginning of the first Offering Period to be affected.
Absent action by the Board, each Offering Period shall be for the periods
described in Section 2(l) of this Plan. No Offering Period shall exceed
twenty-four (24) months in length.

     5. Participation.

     (a) An eligible Employee may become a Participant in the Plan by completing
a subscription agreement authorizing payroll deductions in the form provided by
the Company and filing it with the Company's payroll office prior to the
applicable Enrollment Date.

     (b) Payroll deductions for a Participant shall commence on the first
payroll period following the Enrollment Date and shall end on the last payroll
period in the Offering Period, unless sooner terminated by the Participant as
provided in Section 10.

     6. Payroll Deductions.

     (a) At the time a Participant files his or her subscription agreement, he
or she shall elect to have payroll deductions made on each pay day during the
Offering Period in an amount not exceeding fifteen percent (15%) of the
Compensation which he or she receives on each pay day during the Offering
Period, and the aggregate of such payroll deductions during the Offering Period
shall not exceed fifteen percent (15%) of the Participant's Compensation during
said Offering Period.

     (b) All payroll deductions made for a Participant shall be credited to his
or her account under the Plan and will be withheld in whole percentages only. A
Participant may not make any additional payments into such account.

     (c) A Participant may discontinue his or her participation in the Plan as
provided in Section 10, or may increase or decrease the rate of his or her
payroll deductions once during the current Purchase Period by filing with the
Company a new subscription agreement authorizing such a change in the payroll
deduction rate. A reduction to a 0% rate of contribution shall be treated as a
withdrawal from the Plan effective with the following Purchase Period unless
such rate is increased prior to the following Purchase Period. The change in
rate shall be effective with the first full payroll period following such
advance notice period as the Company shall specify. A Participant's subscription
agreement shall remain in effect for successive Purchase Periods and Offering
Periods unless terminated as provided in Section 10. A Participant may at any
time elect to have his or her participation agreement become irrevocable for
such period of time as he or she may designate.

     (d) Notwithstanding the foregoing, to the extent necessary to comply with
Section 423(b)(8) of the Code and Section 3(b) herein, a Participant's payroll
deductions may be decreased to 0% at such time during any Purchase Period which
is scheduled to end during the current calendar year (the "Current Purchase
Period") that the aggregate of all payroll deductions which were previously used
to purchase stock under the Plan in a prior Purchase Period which ended during
that calendar year plus all payroll deductions accumulated with respect to the
Current Purchase Period equal $21,250. The Company may provide either (i) that
payroll deductions shall recommence at the rate provided in such Participant's
subscription agreement at the beginning of the first Purchase Period which is
scheduled to end in the following calendar year, unless terminated by the
Participant as provided in Section 10, or (ii) that participation shall
recommence only upon filing a new enrollment form following such waiting period
as the Company shall specify.

     (e) At the time the purchase right is exercised, in whole or in part, or at
the time some or all of the Company's Common Stock issued under the Plan is
disposed of, the Participant must make adequate provision for the Company's
federal, state, or other tax withholding obligations, if any, which arise upon
the exercise of the purchase right or the disposition of the Common Stock. At
any time, the Company may, but will not be obligated to, withhold from the
Participant's compensation the amount necessary for the Company to meet
applicable withholding obligations, including any withholding required to make
available to the

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Company any tax deductions or benefit attributable to sale or early disposition
of Common Stock by the Employee.

     7. Grant of Purchase Right. On the Enrollment Date of each Offering Period,
each eligible Employee participating in such Offering Period shall be granted a
purchase right to purchase on each Exercise Date during such Offering Period (at
the applicable Purchase Price) up to a number of shares of the Company's Common
Stock determined by dividing such Employee's payroll deductions accumulated
prior to such Exercise Date and retained in the Participant's account as of the
Exercise Date by the applicable Purchase Price; provided that such purchase
shall be subject to the limitations set forth in Section 3(b) and 12 hereof.
Exercise of the purchase right shall occur as provided in Section 8, unless the
Participant has withdrawn pursuant to Section 10, and the purchase right shall
expire on the last day of the Offering Period.

     8. Exercise of Purchase Right. Unless a Participant withdraws from the Plan
as provided in Section 10 below, his or her purchase right for the purchase of
shares of Common Stock will be exercised automatically on each Exercise Date,
and the maximum number of full shares subject to the purchase right shall be
purchased for such Participant at the applicable Purchase Price with the
accumulated payroll deductions in his or her account. No fractional shares will
be purchased. Any payroll deductions accumulated in a Participant's account
which are not sufficient to purchase a full share shall be retained in the
Participant's account for the subsequent Purchase Period, subject to earlier
withdrawal by the Participant as provided in Section 10. During a Participant's
lifetime, a Participant's purchase right to purchase shares hereunder is
exercisable only by him or her.

     9. Delivery. As promptly as practicable after each Exercise Date on which a
purchase of shares occurs, the Company shall arrange the delivery of purchased
shares to a directed brokerage account. Certificates representing the shares
that were purchased by each Participant will remain with the brokerage account
until such time as the Participant (or beneficiary) requests that their shares
be transferred out of the brokerage account.

     10. Withdrawal; Termination of Employment.

     (a) A Participant may, subject to the terms of any irrevocable
participation agreement elected by the Participant, withdraw all but not less
than all the payroll deductions credited to his or her account and not yet used
to exercise his or her purchase right under the Plan at any time by giving
written notice to the Company in the form provided by the Company. All of the
Participant's payroll deductions credited to his or her account will be paid to
such Participant promptly after receipt of notice of withdrawal and such
Participant's purchase right for the Offering Period will be automatically
terminated, and no further payroll deductions for the purchase of shares will be
made during the Offering Period. If a Participant withdraws from an Offering
Period, payroll deductions will not resume at the beginning of the succeeding
Offering Period unless the Participant delivers to the Company a new
subscription agreement.

     (b) Upon a Participant's ceasing to be an Employee for any reason or upon
termination of a Participant's employment relationship (as described in Section
2(g)), the payroll deductions credited to such Participant's account during the
Offering Period but not yet used to exercise the purchase right will be returned
to such Participant or, in the case of his or her death, to the person or
persons entitled thereto under Section 14, and such Participant's purchase right
will be automatically terminated. The Company may reduce the amount returned to
a Participant by the amount of any outstanding debts that the Participant owes
to either the Company or a Subsidiary.

     11. Interest. No interest shall accrue on the payroll deductions of a
Participant in the Plan.

     12. Stock.

     (a) The maximum number of shares of the Company's Common Stock which shall
be made available for sale under the Plan shall be 500,000 shares (the "Pool"),
subject to adjustment upon changes in capitalization of the Company as provided
in Section 18. On the first Trading Day of each of the twenty calendar years
beginning in 2002 and ending in 2021, if the Pool is less than the amount equal
to one percent (1%) of the outstanding Common Stock (the "Target Amount"), the
Pool shall be increased by the

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difference between the Target Amount and the then current size of the Pool, up
to a maximum of 500,000 shares in any calendar year. If on a given Exercise Date
the number of shares with respect to which purchase rights are to be exercised
exceeds the number of shares then available under the Plan, the Company shall
make a pro rata allocation of the shares remaining available for purchase in as
uniform a manner as shall be practicable and as it shall determine to be
equitable.

     (b) The Participant will have no interest or voting right in shares covered
by this purchase right until such purchase right has been exercised.

     (c) Shares to be delivered to a Participant under the Plan will be
registered in the name of the Participant or in the name of the Participant and
his or her spouse.

     13. Administration. The Plan shall be administered by the Board of the
Company or a committee of one or more members of the Board as appointed by the
Board. Committee members serve for the period of time specified by the Board of
Directors and can be removed from the committee by the Board at any time. The
Board or its committee shall have full and exclusive discretionary authority to
construe, interpret and apply the terms of the Plan, to determine eligibility
and to adjudicate all disputed claims filed under the Plan. Every finding,
decision and determination made by the Board or its committee shall, to the full
extent permitted by law, be final and binding upon all parties.

     14. Designation of Beneficiary.

     (a) A Participant may file a written designation of a beneficiary who is to
receive any shares and cash, if any, from the Participant's account under the
Plan in the event of such Participant's death subsequent to an Exercise Date on
which the purchase right is exercised but prior to delivery to such Participant
of such shares and cash. In addition, a Participant may file a written
designation of a beneficiary who is to receive any cash from the Participant's
account under the Plan in the event of such Participant's death prior to
exercise of the purchase right. If a Participant is married and the designated
beneficiary is not the spouse, spousal consent shall be required for such
designation to be effective.

     (b) Such designation of beneficiary may be changed by the Participant (and
his or her spouse, if any) at any time by written notice. In the event of the
death of a Participant and in the absence of a beneficiary validly designated
under the Plan who is living at the time of such Participant's death, the
Company shall deliver such shares and/or cash to the executor or administrator
of the estate of the Participant, or if no such executor or administrator has
been appointed (to the knowledge of the Company), the Company, in its
discretion, may deliver such shares and/or cash to the spouse or to any one or
more dependents or relatives of the Participant, or if no spouse, dependent or
relative is known to the Company, then to such other person as the Company may
designate.

     15. Transferability. Neither payroll deductions credited to a Participant's
account nor any rights with regard to the exercise of a purchase right or to
receive shares under the Plan may be assigned, transferred, pledged or otherwise
disposed of in any way (other than by will, the laws of descent and distribution
or as provided in Section 14 hereof) by the Participant. Any such attempt at
assignment, transfer, pledge or other disposition shall be without effect,
except that the Company may treat such act as an election to withdraw funds from
an Offering Period in accordance with Section 10.

     16. Use of Funds. All payroll deductions received or held by the Company
under the Plan may be used by the Company for any corporate purpose, and the
Company shall not be obligated to segregate such payroll deductions.

     17. Reports. Individual accounts will be maintained for each Participant in
the Plan. Statements of account will be given to participating Employees at
least annually, which statements will set forth the amounts of payroll
deductions, the Purchase Price, the number of shares purchased and the remaining
cash balance, if any.

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     18.Adjustments Upon Changes in Capitalization, Dissolution, Merger or Asset
        Sale.

     (a) Changes in Capitalization. Subject to any required action by the
shareholders of the Company, the Reserves as well as the price per share of
Common Stock covered by each purchase right under the Plan which has not yet
been exercised, shall be proportionately adjusted for any increase or decrease
in the number of issued shares of Common Stock resulting from a stock split,
reverse stock split, stock dividend, combination or reclassification of the
Common Stock, or any other increase or decrease in the number of shares of
Common Stock effected without receipt of consideration by the Company; provided,
however, that conversion of any convertible securities of the Company shall not
be deemed to have been "effected without receipt of consideration." Such
adjustment shall be made by the Board, whose determination in that respect shall
be final, binding and conclusive. Except as expressly provided herein, no issue
by the Company of shares of stock of any class, or securities convertible into
shares of stock of any class, shall affect, and no adjustment by reason thereof
shall be made with respect to, the number or price of shares of Common Stock
subject to a purchase right. The Board may, if it so determines in the exercise
of its sole discretion, make provision for adjusting the Reserves, as well as
the price per share of Common Stock covered by each outstanding purchase right,
in the event the Company effects one or more reorganizations, recapitalizations,
rights offerings or other increases or reductions of shares of its outstanding
Common Stock.

     (b) Dissolution or Liquidation. In the event of the proposed dissolution or
liquidation of the Company, the Offering Periods will terminate immediately
prior to the consummation of such proposed action, unless otherwise provided by
the Board.

     (c) Merger or Asset Sale. In the event of a proposed sale of all or
substantially all of the assets of the Company, or the merger of the Company
with or into another corporation, each purchase right under the Plan shall be
assumed or an equivalent purchase right shall be substituted by such successor
corporation or a parent or subsidiary of such successor corporation, unless the
Board determines, in the exercise of its sole discretion and in lieu of such
assumption or substitution, to shorten the Offering Periods then in progress by
setting a new Exercise Date (the "New Exercise Date"). If the Board shortens the
Offering Periods then in progress in lieu of assumption or substitution in the
event of a merger or sale of assets, the Board shall notify each Participant in
writing, at least ten (10) days prior to the New Exercise Date, that the
Exercise Date for his purchase right has been changed to the New Exercise Date
and that his purchase right will be exercised automatically on the New Exercise
Date, unless prior to such date he has withdrawn from the Offering Period as
provided in Section 10. For purposes of this Section, a purchase right granted
under the Plan shall be deemed to be assumed or substituted if accomplished in
accordance with Section 424 of the Code.

     19. Amendment or Termination.

     (a) The Board of Directors of the Company may at any time and for any
reason terminate or amend the Plan. Except as provided in Section 18, no such
termination can affect purchase rights previously granted, provided that an
Offering Period may be terminated by the Board of Directors on any Exercise Date
if the Board determines that the termination of the Plan is in the best
interests of the Company and its shareholders. Except as provided in Section 18,
no amendment may make any change in any purchase right theretofore granted which
adversely affects the rights of any Participant. To the extent necessary to
comply with Rule 16b-3 or under Section 423 of the Code (or any successor rule
or provision or any other applicable law or regulation), the Company shall
obtain shareholder approval in such a manner and to such a degree as required.

     (b) Without shareholder consent and without regard to whether any
Participant rights may be considered to have been "adversely affected," the
Board (or its committee) shall be entitled to change the Purchase Periods and/or
Offering Periods (subject to Section 4), limit the frequency and/or number of
changes in the amount withheld during Purchase Periods and/or Offering Periods,
establish the exchange ratio applicable to amounts withheld in a currency other
than U.S. dollars, permit payroll withholding in excess of the amount designated
by a Participant in order to adjust for delays or mistakes in the Company's
processing of properly completed withholding elections, establish reasonable
waiting and adjustment periods and/or accounting and crediting procedures to
ensure that amounts applied toward the purchase of Common Stock for each
Participant properly correspond with amounts withheld from the Participant's
Compensation, and

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establish such other limitations or procedures as the Board (or its committee)
determines in its sole discretion advisable which are consistent with the Plan.

     20. Notices. All notices or other communications by a Participant to the
Company under or in connection with the Plan shall be deemed to have been duly
given when received in the form specified by the Company at the location, or by
the person, designated by the Company for the receipt thereof.

     21. Conditions Upon Issuance of Shares. Shares shall not be issued with
respect to a purchase right unless the exercise of such purchase right and the
issuance and delivery of such shares pursuant thereto shall comply with all
applicable provisions of law, domestic or foreign, including, without
limitation, the Securities Act of 1933, as amended, the Securities Exchange Act
of 1934, as amended, the rules and regulations promulgated thereunder, and the
requirements of any stock exchange upon which the shares may then be listed, and
shall be further subject to the approval of counsel for the Company with respect
to such compliance.

     22. Term of Plan. The Plan is effective as of June 1, 2001. The Plan shall
continue in effect through December 31, 2021 unless sooner terminated under
Section 19.

     23. Automatic Transfer to Low Price Offering Period. If the Fair Market
Value of the Common Stock on any Exercise Date in an Offering Period is lower
than the Enrollment Date Price of such Offering Period, then all Participants in
such Offering Period shall be automatically withdrawn from such Offering Period
immediately after the exercise of their purchase rights on such Exercise Date
and automatically reenrolled in the immediately following Offering Period as of
the first day thereof.

     24. Execution. To record the adoption of this amended and restated Plan by
the Board, the Company has caused its duly authorized officer to sign below.

                                          CORIXA CORPORATION

                                          By
                                            ------------------------------------

                                          Title
                                             -----------------------------------

                                       B-7

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