Document:

Amendment No. 1 to License Agreement dated January 30, 2009

 Exhibit 10.1 
 AMENDMENT NO. 1 
 to 
 LICENSE AGREEMENT 
 THIS AMENDMENT NO. 1 (“Amendment No. 1”),
effective as of this 30th day of January, 2009 (the “Effective Date”), by and between BUKWANG PHARM., CO., LTD., a Korean corporation with its principal offices at 398-1, Daebang-Dong, Dongjak-Ku, Seoul 156-020, Korea
(“Bukwang”) and PHARMASSET, INC., a Delaware corporation with its principal offices at 303-A College Road East, Princeton, New Jersey 08540, USA (“Pharmasset”). 
 WITNESSETH: 
 WHEREAS, Bukwang and Pharmasset have entered
into a license agreement dated as of June 23, 2005 (the “License Agreement”), pursuant to which Bukwang granted Pharmasset certain rights in and to the compound known as L-FMAU and sometimes also referred to as
“clevudine;” and 
 WHEREAS, Bukwang and Pharmasset now wish to amend certain terms of the License Agreement as set forth herein.

 NOW, THEREFORE, in consideration of the premises and the covenants herein contained, the parties agree as follows: 
  

	1.	Capitalized terms used herein and not otherwise defined shall have the meanings given to them in the License Agreement. 

  

	2.	Section 1.35 shall be deleted in its entirety and replaced with the following: 

 “Territory” shall mean all the countries in Central America, North America, South America, Europe, the Caribbean and Australia, Israel, Japan, New Zealand and Taiwan, including those countries set
forth on Exhibit E, and any and all territories and possessions of any such countries. 
  

	3.	Exhibit E to the License Agreement shall be amended to include the countries of Australia, Japan, New Zealand and Taiwan. 

  

	4.	Except as expressly amended by this Amendment No. 1, the License Agreement shall remain unchanged and shall continue in full force and effect. 

  

	5.	This Amendment No. 1 and all amendments, modifications, alterations, or supplements hereto, and the rights of the parties hereunder, shall be construed under and governed by
the laws of the state of Georgia exclusive of its conflicts of laws principles. 

  

	6.	This Amendment No. 1 may be executed in one or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same
instrument. 

 [Signature Page Follows] 

 IN WITNESS WHEREOF, Pharmasset and Bukwang have caused this Amendment No. 1 to be signed by their
duly authorized representatives, under seal, as of the day and year indicated above. 
  

			
		 	BUKWANG PHARM. CO., LTD.
		
	By:	 	 /s/ Sung Koo Lee

		
	Name:	 	 Sung Koo Lee

		
	Title:	 	 President and CEO

		
		 	PHARMASSET, INC.
		
	By:	 	 /s/ P. Schaefer Price

		
	Name:	 	 P. Schaefer Price

		
	Title:	 	 President and CEO

 SIGNATURE PAGE TO AMENDMENT
NO. 1 TO BUKWANG-PHARMASSET CLV LICENSE AGREEMENTAmended and Restated Supplemental Executive Retirement Plan

 Exhibit 10.4 
 THE HOLOGIC, INC. 
 AMENDED AND RESTATED 
 SUPPLEMENTAL EXECUTIVE RETIREMENT PLAN 
 Amended and Restated 
 December 11, 2008 

 THE HOLOGIC, INC. 
 AMENDED AND RESTATED 
 SUPPLEMENTAL EXECUTIVE RETIREMENT PLAN 
 ARTICLE I - PURPOSE; EFFECTIVE DATE 
 1.1 Purpose. The purpose of this HOLOGIC, INC. AMENDED AND RESTATED SUPPLEMENTAL EXECUTIVE RETIREMENT PLAN (hereinafter, the “Plan”) is to permit a select group of management or highly compensated employees of
Hologic, Inc. (and its selected subsidiaries and/or affiliates) to defer the receipt of income which would otherwise become payable to them. It is intended that this Plan, by providing these eligible employees an opportunity to defer the receipt of
income, will assist in the retaining and attracting individuals of exceptional ability and by providing an additional opportunity to save for retirement beyond Code limitations imposed on qualified retirement plans. This Plan is intended to be
“unfunded” for purposes of the Employee Retirement Income Security Act of 1974, as amended (“ERISA”). 
 1.2
Effective Date. This Plan was originally adopted by the Company effective as of October 15, 2006. The Plan, as amended and restated herein, shall be effective as of December 1, 2008 (the “Effective Date”). It is the
intent that all of the amounts deferred and benefits provided under this Plan will comply with the terms of Section 409A of the Code and the final Treasury Regulations promulgated thereunder. 
 1.3 Unfunded Plan. This plan is an unfunded top-hat plan maintained primarily to provide deferred compensation benefits for a “select
group of management or highly-compensated employees” within the meaning of Sections 201, 301, and 401 of ERISA, and therefore is exempt from the provisions of Parts 2, 3 and 4 of Title I of ERISA. 
 ARTICLE II - DEFINITIONS 
 For
the purpose of this Plan, the following terms shall have the meanings indicated, unless the context clearly indicates otherwise: 
 2.1
Account(s). “Account(s)” means the notional account or accounts maintained on the books of the Company used solely to calculate the amount payable to each Participant under this Plan and shall not constitute a separate fund
of assets. Account(s) shall be deemed to exist from the time amounts are first credited to such Account(s) until such time that the entire Account balance has been distributed in accordance with this Plan. The Accounts available for each Participant
shall be identified as: 
 (a) Deferral Account; 
  

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 (b) In-Service Account; and, 
 (c) Retention Account. 
 2.2
Beneficiary. “Beneficiary” means the person, persons or entity as designated by the Participant, entitled under Article VI to receive any Plan benefits payable after the Participant’s death. 
 2.3 Board. “Board” means the Board of Directors of the Company. 
 2.4 Change of Control. “Change of Control” means: 
 (a) a change in the ownership or effective control of the Company or in the ownership of a substantial portion of the assets of the Company, as defined and determined under Section 409A(a)(2)(A)(v) of the Code
and Treasury Regulation Section 1.409A-3(i)(5). Without in any way limiting the scope of the preceding sentence, a Change of Control shall be deemed to occur on the date upon which one of the following events occurs: 
 i. any one person (as such term is used in Sections 13(d) and 14(d)(2) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”),
or more than one person acting as a group (as determined under Treasury Regulation Section 1.409A-3(i)(5)(v)(B)), acquires ownership of stock of the Company that, together with stock held by such person or group, constitutes more than 50% of
either the total fair market value or total voting power of the stock of the Company. However, if any one person, or more than one person acting as a group, is considered to own more than 50% of the total fair market value or total voting power of
the stock of the Company, the acquisition of additional control of the Company by the same person or persons is not considered to cause a change of control of the Company; or 
 ii. any one person (as such term is used in the Exchange Act), or more than one person acting as a group (as determined under Treasury Regulation
Section 1.409A-3(i)(5)(v)(B)), acquires (or has acquired during the 12-month period ending on the date of the most recent acquisition by such person or persons) ownership of stock of the Company possessing 35% or more of the total voting power
of the Company. However, if any one person, or more than one person acting as a group, is considered to own more than 35% of the total voting power of the stock of the Company, the acquisition of additional control of the Company by the same person
or persons is not considered to cause a change of control of the Company; or 
 iii. a majority of members of the Board is replaced during
any 12-month period by directors whose appointment or election is not endorsed by a majority of the members of the Board prior to the date of the appointment or election; or 
 iv. any one person (as such term is used in the Exchange Act), or more than one person acting as a group (as determined under Treasury Regulation
Section 1.409A-3(i)(5)(v)(B)), acquires (or has acquired during the 12-month period ending on the date of the most recent 

  

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acquisition by such person or persons) assets from the Company that have a total gross fair market value equal to or more than 40% of the total gross fair
market value of all of the assets of the Company immediately prior to such acquisition or acquisitions. For this purpose, gross fair market value means the value of the assets of the Company, or the value of the assets being disposed of, determined
without regard to any liabilities associated with such assets. 
 2.5 Code. “Code” means the Internal Revenue Code of
1986, as amended, and any successor thereto. 
 2.6 Committee. “Compensation Committee” means the Compensation
Committee appointed by the Board to administer the Plan pursuant to Article VII. 
 2.7 Company. “Company” means
Hologic, Inc., a Delaware corporation, and any directly or indirectly affiliated subsidiary corporations. 
 2.8 Compensation.
“Compensation” means the base salary payable to Participant and bonus or incentive compensation earned by a Participant with respect to employment services performed for the Company by the Participant and considered to be “wages”
for purposes of federal income tax withholding. For purposes of this Plan only, Compensation shall be calculated before reduction for any amounts deferred by the Participant pursuant to the Company’s tax qualified plans which may be maintained
under Section 401(k) or Section 125 of the Code, but shall exclude “wages” associated with the exercise of stock options by Participant or income arising from other equity instruments (e.g., stock units, restricted stock units or
restricted stock) awarded to a Participant. Inclusion of any other forms of compensation, including commissions payable, is subject to Committee approval. 
 2.9 Deferral Election. “Deferral Election” means an irrevocable written commitment made by a Participant to defer a portion of his/her Compensation as set forth in Article III, and as permitted
by the Committee in its sole discretion. The Deferral Election shall apply to each payment of Compensation and/or Performance-Based Compensation payable to a Participant, and shall specify the Account or Accounts to which the Compensation deferred
shall be credited. Such designation shall be made in the form of a whole percentage or an exact stated dollar amount. Such Deferral Election shall be made on an Election Form and at a time deemed acceptable to the Committee. 
 2.10 Deferral Period. “Deferral Period” means each calendar year, except
that if a Participant first becomes eligible after the beginning of a calendar year, the initial Deferral Period shall be the date the Participant first becomes eligible to participate in this Plan through and including December 31st of that calendar year. For purposes of deferrals related to Participant’s annual bonus or other Performance-Based Compensation, “Deferral
Period” shall mean the Company’s fiscal year. 
 2.11 Determination Date. “Determination Date” means each
business day. 
 2.12 Disability. “Disability means the Participant is: (i) unable to engage in any substantial
gainful activity by reason of any medically determinable physical or mental impairment which can be expected to result in death or can be expected to last for a continuous period of not less 

  

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than 12 months, or (ii) by reason of any medically determinable physical or mental impairment which can be expected to result in death or can be
expected to last for a continuous period of not less than 12 months, receiving income replacement or other disability benefits for a period of not less than 3 months under an accident and health plan covering employees of the participant’s
employer. 
 2.13 Distribution Election. “Distribution Election” means the form of payment for benefits payable from
each Account under this Plan, as elected by the Participant on an enrollment form prescribed by the Committee (an “Enrollment Form”). 
 2.14 Financial Hardship. “Financial Hardship” means the occurrence of any of the following events: 
 (a) a
severe financial hardship to the Participant resulting from an illness of accident of the Participant, the Participant’s spouse, a Beneficiary, of the Participant’s dependent (as defined in Section 152 of the Code, without regard to
Sections 152(b)(1), (b)(2), and (d)(1)(B); 
 (b) loss of the Participant’s property due to casualty (including the need to rebuild a
home following damage to a home not otherwise covered by insurance, for example, not as a result of a natural disaster); or 
 (c) other
similar extraordinary and unforeseeable circumstances arising as a result of events beyond the control of the Participant, which may include, if applicable, (x) the imminent foreclosure of or eviction from the Participant’s primary
residence, (y) the need to pay for medical expenses of the Participant or funeral expenses of the Participant’s spouse, a Beneficiary, or the Participant’s dependent (as defined in Section 152 of the Code without regard to
Section 152 (b)(1), (b)(2), and (d)(1)(B). Except as otherwise provided in this clause (c), the purchase of a home and the payment of college tuition are not Financial Hardship. 
 The determination of whether a Financial Hardship exists shall be determined by the Committee after addressing the facts and circumstances of each case and other requirements of the applicable Treasury Regulations.

 2.15 Interest. “Interest” means the amount credited to or charged against a Participant’s Account(s) on each
Determination Date, which shall be based on the Valuation Funds chosen by the Participant as provided in Section 2.24, below and in a manner consistent with Section 4.3, below. Such credits or charges to a Participant’s Account may be
either positive or negative to reflect the increase or decrease in value of the Account in accordance with the provisions of this Plan. 
 2.16 Participant. “Participant” means any individual who is eligible, pursuant to Section 3.1, below, to participate in this Plan, and who either, has elected to defer Compensation under this Plan in accordance
with Article III, below, or who is determined by the Committee in their sole discretion as being eligible to receive a Retention Contribution under this Plan. Such individual shall remain a Participant in this Plan for the period of deferral, or
credit, and until such time as all benefits payable under this Plan have been paid in accordance with the provisions hereof. 
  

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 2.17 Performance-Based Compensation. “Performance-Based Compensation” means
Compensation the amount of which, or the entitlement to which is contingent on the satisfaction of pre-established organizational or individual performance criteria that relate to a particular Performance Period and are not certain to be met at the
time the Deferral Election is made. 
 2.18 Performance Period. “Performance Period” means a continuous period of
service with the Company comprising one entire plan year with respect to which Performance-Based Compensation is earned. 
 2.19
Plan. “Plan” means this Amended and Restated Supplemental Executive Retirement Plan, as amended from time to time. 
 2.20 Retention Contribution. “Retention Contribution” means the annual discretionary contribution, if any, made by the Company to the Participant’s Retention Account under Section 4.4, below. 
 2.21 Retirement. “Retirement” means the termination of a Participant’s employment with the Company, for reasons other than
death or Disability, on or after the earlier of: (a) attainment of age 55 with at least ten (10) years of continuous service with the Company; or (b) attainment of age sixty-five (65). 
 2.22 Specified Employees. “Specified Employees” means “key employees,” as defined in Section 416(i) of the Code
without regard to paragraph (5) thereof, of the Company. 
 2.23 Termination of Employment. A “Termination of
Employment” occurs where the Participant ceases performing any bona fide services for the Company, irrespective of whether the Participant is receiving or scheduled to receive salary continuation, severance, employee benefits or similar
payments or benefits following the cessation of services. 
 2.24 Valuation Funds. “Valuation Funds” means one or
more of the hypothetical investment funds or indices managed by an investment manager that are selected by the Committee. These Valuation Funds are used solely to calculate the Interest that is credited to each Participant’s Account(s) in
accordance with Article IV, below, and does not represent, nor should it be interpreted to convey any beneficial interest or ownership on the part of the Participant in any asset or other property of the Company. Participants may allocate their
Account(s) between Valuation Funds. Exhibit A attached hereto sets forth the available Valuation Funds which may be amended from time to time in the sole and absolute discretion of the Committee. 
 ARTICLE III - ELIGIBILITY AND PARTICIPATION 
 3.1 Eligibility and Participation. 
 (a) Eligibility. Eligibility to participate
in the Plan shall be limited to those senior management employees of the Company who have annual compensation equal to or in excess of $200,000 or who are designated as eligible to participate by the Committee from time to time. 
  

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 (b) Participation. An individual’s participation in the Plan shall be effective upon
notification to the individual by the Committee or its designee of his/her eligibility to participate, and the earlier of a contribution under this Plan being made on behalf of the Participant by the Company or the completion and submission of an
Enrollment Form, Allocation Form (as defined in Section 3.2(b), below), and a Distribution Election to the Committee no later than fifteen (15) days prior to the beginning of the Deferral Period. 
 (c) First-Year Participation. When an individual first becomes eligible to participate in this Plan, a Deferral Election may be submitted
to the Committee within thirty (30) days after the Committee notifies the individual of eligibility to participate. Such Deferral Election will be effective only with regard to Compensation earned and payable following submission of the
Deferral Election to the Committee. 
 3.2 Form of Deferral Election. A Participant may irrevocably elect to make a Deferral
Election no later than fifteen (15) days prior to the beginning of the Deferral Period by submitting the Enrollment Form permitted by the Committee. A Deferral Election with respect to any bonus or Performance-Based Compensation which is based
on services performed over a period of at least twelve (12) months shall be made no later than six (6) months prior to the end of such performance period, provided that: (i) the election to defer is made before the compensation has
become readily ascertainable and (ii) the Participant was employed at the time the performance criteria were established. The Deferral Election shall specify the following: 
 (a) Deferral Amounts; Accounts. A Deferral Election shall be made with respect to each payment of Compensation payable by the Company to a
Participant during the Deferral Period, and shall designate the portion of each deferral that shall be allocated among either the Deferral or In-Service Accounts. In addition, no amounts shall be deferred into an In-Service Account once payments
have commenced under the terms of this Plan and until such time as the entire Account Balance has been completely distributed. The Participant shall set forth the amount of his salary to be deferred as a whole percentage amount of Compensation, and
with respect to the deferral of bonus Compensation or Performance-Based Compensation, a stated dollar amount or a whole percentage amount above a stated dollar amount. 
 (b) Allocation to Valuation Funds. The Participant shall specify in a separate form (known as the “Allocation Form”) filed with the Committee, the Participant’s initial allocation of the
amounts deferred into each Account among the various available Valuation Funds. 
 (c) Maximum Deferral. The maximum amount of
Compensation that may be deferred shall be no more than seventy-five percent (75%) of base salary and one hundred percent (100%) of annual bonus or Performance-Based Compensation. 
 3.3 Period of Commitment. Any Deferral Election made by a Participant with respect to Compensation shall remain in effect for the next
succeeding Deferral Period, and shall remain in effect for all future Deferral Periods unless revoked or amended in writing by the Participant and delivered to the Committee no later than fifteen (15) days prior to the beginning of a subsequent
Deferral Period, except that if a Participant suffers a Disability or terminates employment with Company prior to the 

  

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end of the Deferral Period, the Deferral Period shall end as of the date of Disability or Termination of Employment. Furthermore, a Deferral Election may be
temporarily revoked by operation of Section 5.5, below. 
 3.4 Modification of Deferral Election. Except as provided in
Sections 3.3, above, and 5.5 below, a Deferral Election shall be irrevocable by the Participant during a Deferral Period. 
 3.5 Change
in Status. If the Committee determines that a Participant’s employment performance is no longer at a level that warrants reward through participation in this Plan, but does not terminate the Participant’s employment with Company,
the Participant’s existing Deferral Election shall terminate at the end of the Deferral Period, and no new Deferral Election may be made by such Participant after notice of such determination is given by the Committee, unless the Participant
later satisfies the requirements of Section 3.1. If the Committee, in its sole discretion, determines that the Participant no longer qualifies as a member of a select group of management or highly compensated employees, as determined in
accordance with the ERISA, and interpretive guidance issued thereunder the Committee may, in its sole discretion terminate any Deferral Election for that year, and prohibit the Participant from making any future Deferral Elections. 
 3.6 Defaults in Event of Incomplete or Inaccurate Deferral Elections. In the event that a Participant submits a Deferral Election to the
Committee that contains information necessary to the efficient operation of this Plan which, in the sole discretion of the Committee, is incomplete or inaccurate, the Committee shall be authorized to treat the incomplete or inaccurate Deferral
Election as if the following elections had been made by the Participant, and such information shall be communicated to the Participant: 
 (a)
If no Account is listed - treat as if the Deferral Account was elected; 
 (b) If Accounts listed equal less than 100% - treat as if the
balance was deferred into Deferral Account; 
 (c) If Accounts listed equal more than 100% - proportionately reduce each Account to equal
100%; 
 (d) If In-Service Account is listed, but no deferrals can be made into that Account due to the fact that benefits are being paid
from that In-Service Account, then the amounts elected to be deferred shall be credited to the Deferral Account during such period of payment, after which time the balance of the amounts elected to be deferred shall be credited to a subsequent
In-Service Account with a distribution date as elected or as provided in subsection (i), below; 
 (e) If no Valuation Fund is selected -
treat as if the Money Market Fund was elected; 
 (f) If Valuation Fund(s) selected equal less than 100% - treat as if the Money Market Fund
was elected for remaining balance; 
  

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 (g) If Valuation Fund(s) selected equal more than 100% - proportionately reduce each Valuation Fund to
equal 100%; 
 (h) If no Distribution Election is chosen - treat as if lump sum was elected for In-Service Account and treat as if three
(3) year annual installment method was elected for Deferral Account; and, 
 (i) If no time of payment is chosen for In-Service Account
-treat as if the earliest possible date available under the provisions of Section 5.3, below, was elected. 
 ARTICLE IV - DEFERRED
COMPENSATION ACCOUNT 
 4.1 Accounts. The Compensation deferred by a Participant under the Plan, and Interest shall be
credited to the Participant’s Account(s) as selected by the Participant; any Retention Contributions and Interest thereon shall be credited to the Participant’s Retention Account. Separate accounts may be maintained on the books of the
Company to reflect the different Accounts chosen by the Participant, and the Participant shall designate the portion of each deferral that will be credited to each Account as set forth in Section 3.2(a), above. These Accounts shall be used
solely to calculate the amount payable to each Participant under this Plan and shall not constitute a separate fund of assets. 
 4.2
Timing of Credits; Withholding. A Participant’s deferred Compensation shall be credited to each Account designated by the Participant as soon as administratively practical after the date the Compensation deferred would have
otherwise been payable to the Participant. Any Retention Contributions shall be credited to the Retention Account as set forth in Section 4.5, below. Any withholding of taxes or other amounts with respect to deferred Compensation or other
amounts credited under this Plan that is required by local, state or federal law shall be withheld from the Participant’s corresponding non-deferred portion of the Compensation to the maximum extent possible, and any remaining amount shall
reduce the amount credited to the Participant’s Account in a manner specified by the Committee. 
 4.3 Valuation Funds. A
Participant shall designate, at a time and in a manner acceptable to the Committee, one or more Valuation Funds for each Account for the sole purpose of determining the amount of Interest to be credited or debited to such Account. Such election
shall designate the portion of each deferral of Compensation made into each Account that shall be allocated among the available Valuation Fund(s), and such election shall apply to each succeeding deferral of Compensation until such time as the
Participant shall file a new election with the Committee. Upon notice to the Committee, Participants shall also be permitted to reallocate the balance in each Valuation Fund among the other available Valuation Funds as determined by the Committee.
The manner in which such elections shall be made and the frequency with which such elections may be changed and the manner in which such elections shall become effective shall be determined in accordance with the procedures to be adopted by the
Committee or its delegates from time to time. As of the Effective Date, such elections may be made on a daily basis electronically, and such elections shall become effective on the date made or the next available Determination Date. 
  

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 4.4 Retention Contributions. Company may make a discretionary contribution to each eligible
Participant’s Retention Account as soon as is practical after the close of the Company’s fiscal year, but in no event later than sixty (60) days following the close of such fiscal year. The amount of the credit shall be determined by
the Committee in its sole discretion, and each year, the Committee shall have the discretion to increase or decrease the Retention Contribution from prior years, or to eliminate the contribution totally for any given year. 
 4.5 Determination of Accounts. Each Participant’s Account as of each Determination Date shall consist of the balance of the Account as
of the immediately preceding Determination Date, adjusted as follows: 
 (a) New Deferrals. Each Account shall be increased by
any deferred Compensation credited since such prior Determination Date in the proportion chosen by the Participant, except that no amount of new deferrals shall be credited to an Account at the same time that a distribution is to be made from that
Account. 
 (b) Company Contributions. Each Account shall be increased by any Retention Contributions credited since such prior
Determination as set forth above in sections 4.4 or as otherwise directed by the Committee. 
 (c) Distributions. Each Account
shall be reduced by the amount of each benefit payment made from that Account since the prior Determination Date. Distributions shall be deemed to have been made proportionally from each of the Valuation Funds maintained within such Account based on
the proportion that such Valuation Fund bears to the sum of all Valuation Funds maintained within such Account for that Participant as of the Determination Date immediately preceding the date of payment. 
 (d) Interest. Each Account shall be increased or decreased by the Interest credited to such Account since such Determination Date as though
the balance of that Account as of the beginning of the current month had been invested in the applicable Valuation Funds chosen by the Participant. 
 4.6 Vesting of Accounts. Each Participant shall be vested in the amounts credited to such Participant’s Account and Interest thereon as follows: 
 (a) Amounts Deferred. A Participant shall be one hundred percent (100%) vested at all times in the amount of Compensation elected to be
deferred under this Plan to the Deferral Account and In-Service Account, if any, including any Interest thereon. 
 (b) Retention
Contributions. Each separate Retention Contribution, if any, to a Participant’s Retention Account, including any Interest thereon, shall be 33.33% vested on the last day of the fiscal year immediately following the fiscal year to which
the Retention Contribution is attributable, provided, that the Participant remains employed by the Company on such date, and vested in an additional 33.33% of such Retention Contribution on the last day of the second and third fiscal years,
respectively, following the fiscal year to which the Retention Contribution is 

  

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attributable, provided, that the Participant remains employed by the Company on each such date. If the Participant fails to remain employed with the Company
through the vesting dates and the Retention Contribution is not otherwise vested as providing in the following sentence, then the unvested portion of the Retention Contribution and any Interest thereon shall be forfeited and returned to the Company.
Notwithstanding the previous sentence or anything else herein to the contrary, a Participant’s Retention Account shall (i) be one hundred percent (100%) vested upon the death or Disability of the Participant or a Change of Control or
(ii) be one hundred percent (100%) vested as otherwise provided by the Committee in its sole discretion. 
 (c) Statement of
Accounts. The Committee shall direct the Plan’s third-party administrator to provide to each Participant a statement showing the balances in the Participant’s Account on a quarterly basis. 
 ARTICLE V - PLAN BENEFITS 
 5.1
Deferral Account. The vested portion of a Participant’s Deferral Account shall be distributed to the Participant upon the Termination of Employment with the Company. 
 (a) Timing of Payment. Subject to Section 5.8, benefits payable from the
Deferral Account shall commence on or about the December 15th immediately following the date of the Participant’s Termination of
Employment, or if later forty-five (45) days following the Participant’s Termination of Employment, and subsequent payments, if the Form of Payment selected provides for subsequent payments, shall be made on or about each succeeding
December 15th. 
 (b) Form of Payment. The form of benefit payment from the Deferral Account shall be that form selected
by the Participant in the first Deferral Election which designated a portion of the Compensation deferred be allocated to the Deferral Account, and as permitted pursuant to Section 5.9 below, except that if the Participant terminates employment
prior to Retirement, in which event, the Deferral Account shall be paid in the form of a lump sum payment. 
 5.2 Retention
Account. The vested portion of the Participant’s Retention Account shall be distributed to the Participant upon the Termination of Employment with the Company. 
 (a) Timing of Payment. Subject to Section 5.8, benefits payable from the
Retention Account shall commence on or about the December 15th immediately following the date of the Participant’s Termination of
Employment, or if later forty-five (45) days following the Participant’s Termination of Employment, and subsequent payments, if the Form of Payment selected provides for subsequent payments, shall be made on or about each succeeding
December 15th. 
 (b) Form of Payment. The form of benefit payment from the Retention Account shall be made in that form
selected by the Participant in the Distribution Election set forth in the Enrollment Form filed with the Committee coincident with the initial crediting of amounts to the Retention Account, and as permitted pursuant to Section 5.9 below, except
that if the Participant terminates employment prior to Retirement, in which event, the Retention Account shall be paid in the form of a lump sum payment. 
  

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 5.3 In-Service Account. The vested portion of a Participant’s In-Service Account shall
generally be distributed to the Participant upon the date chosen by the Participant, or if earlier the Participant’s Termination of Employment. 
 (a) Timing of Payment. Subject to Section 5.8, benefits under this section shall
be payable on or about January 15th of the year specified in the first Deferral Election which designated a portion of the Compensation
deferred be allocated to the In-Service Account and subsequent payments. In no event shall the date selected be earlier than the first day of the sixth calendar year following the initial filing of the Deferral Election with respect to that
In-Service Account. In the event that the Participant terminates employment with the Company prior to the date so specified, the benefits under this section shall commence on Participant’s Termination of Employment. For purposes of this
Section 5.3(a), any benefit payments due on Termination of Employment shall commence on or about the December 15th immediately following
the date of the Participant’s Termination of Employment, or if later forty-five (45) days following the Participant’s Termination of Employment. 
 (b) Form of Payment. The form of benefit payment from the In-Service Account shall
be that form selected by the Participant pursuant to Section 5.9, below, except that if the Participant terminates employment with the Company prior to the date so specified, then the In-Service Account shall be paid in the form of a lump sum
payment. If the Form of Payment selected provides for subsequent payments, subsequent payments shall be made on or about each succeeding December 15th.  
 (c) Change of Time and/or Form of Payment. The Participant may, subsequently amend the form of payment or the
intended date of payment to a date later than that date initially chosen, by filing such amendment with the Committee no later than twelve (12) months prior to the current date of payment. The Participant may file this amendment, provided that
each amendment must provide for a payout under this paragraph at a date no earlier than five (5) years after the date of payment in force immediately prior to the filing of such request, and the amendment may not take effect for twelve
(12) months after the request is made. 
 5.4 Death Benefit. Upon the death of a Participant prior to the commencement of
benefits under this Plan from any particular Account, Company shall pay to the Participant’s Beneficiary an amount equal to the vested Account balance in that Account in the form of a lump sum payment. In the event of the death of the
Participant after the commencement of benefits under this Plan from any Account, the benefits from that Account(s) shall be paid to the Participant’s designated Beneficiary from that Account at the same time and in the same manner as if the
Participant had survived. 
 5.5 Hardship Distributions. Upon a finding that a Participant has suffered a Financial Hardship,
the Committee shall terminate the existing Deferral Election, and/or make distributions from any or all of the Participant’s Accounts. The amount of such distribution shall be limited to the amount reasonably necessary to meet the
Participant’s needs resulting from the Financial Hardship plus 

  

 11 

 
amounts necessary to pay taxes reasonably anticipated as a result of the distribution, after taking into account the extent to which such Financial Hardship
is or may be relieved through the reimbursement or compensation by insurance, or otherwise or by liquidation of the Participant’s assets (to the extent that liquidation of such assets would not itself cause severe financial hardship). The
amount of such distribution will not exceed the Participant’s vested Account balances. If payment is made due to Financial Hardship, the Participant’s deferrals under this Plan shall cease for the period of the Financial Hardship and for
twelve (12) months thereafter. If the Participant is again eligible to participate, any resumption of the Participant’s deferrals under the Plan after such twelve (12) month period shall be made only at the election of the Participant
in accordance with Article III herein. 
 5.6 Change of Control Distributions. Upon the occurrence of a Change of Control,
benefits payable from the Deferral and Retention Accounts shall be distributed to the Participant within forty-five (45) days following the Change of Control. 
 5.7 Disability Distributions. Upon a finding that a Participant has suffered a Disability, the Committee may make distributions from any or all of the Participant’s Accounts. The amount of such
distribution shall be limited to the amount reasonably necessary to meet the Participant’s needs resulting from the Disability. 
 5.8
Payment to Specified Employees. Payments of benefits from the Deferral Account, Retention Account and benefits payable from an In-Service Account caused by the Termination of Employment of a Participant who is determined to meet the
definition of Specified Employee shall be payable as otherwise provided, except that the initial payment shall be made no earlier than the six (6) months following the Termination of Employment with the Company (or, if earlier than the end of
the six (6) month period, the date of death of the Specified Employee). 
 5.9 Form of Payment. Unless otherwise specified
in this Article, the benefits payable from any Account under this Plan shall be paid in the form of benefit as provided below, and specified by the Participant in the Distribution Election applicable to that Account at the time of the initial
deferral or credit to that Account. The permitted forms of benefit payments are: 
 (a) A lump sum amount which is equal to the vested Account
balance; and 
 (b) Annual installments for a period of up to fifteen (15) years (or in the event of payment of the In-Service Account,
a maximum of five (5) years) where the annual payment shall be equal to the balance of the Account immediately prior to the payment, multiplied by a fraction, the numerator of which is one (1) and the denominator of which commences at the
number of annual payment initially chosen and is reduced by one (1) in each succeeding year. Interest on the unpaid balance shall be based on the most recent allocation among the available Valuation Funds chosen by the Participant, made in
accordance with Section 4.3, above. 
 5.10 Small Account. If the total of a Participant’s vested, unpaid Account
balance as of the time the payments are to commence from the Participant’s Account is less than the minimum prescribed, the remaining unpaid, vested Account shall be paid in a lump sum, notwithstanding any election by the Participant to the
contrary. Such minimums shall be $5,000 for any In-Service Account and $10,000 for any Deferral or Retention Account. 
  

 12 

 5.11 Withholding; Payroll Taxes. Company shall withhold from any payment made pursuant to
this Plan any taxes required to be withheld from such payments under local, state or federal law. A Beneficiary, however, may elect not to have withholding of federal income tax pursuant to Section 3405(a)(2) of the Code, or any successor
provision thereto. 
 5.12 Payment to Guardian. If a Plan benefit is payable to a minor or a person declared incompetent or to
a person incapable of handling the disposition of the property, the Committee may direct payment to the guardian, legal representative or person having the care and custody of such minor, incompetent or person. The Committee may require proof of
incompetency, minority, incapacity or guardianship as it may deem appropriate prior to distribution. Such distribution shall completely discharge the Committee and Company from all liability with respect to such benefit. 
 5.13 Effect of Payment. The full payment of the applicable benefit under this Article V shall completely discharge all obligations on the
part of the Company to the Participant (and the Participant’s Beneficiary) with respect to the operation of this Plan, and the Participant’s (and Participant’s Beneficiary’s) rights under this Plan shall terminate. 
 5.14 Forfeiture. In the event a Participant is terminated for “cause,” then his Retention Account shall be immediately forfeited
without regard to whether or not he is vested or unvested in such Retention Account. For purposes of this Plan, “cause” shall mean (i) an act or acts of personal dishonesty taken by the Participant and intended to result in
substantial personal enrichment of the Participant at the expense of the Company; (ii) material violation of the Company’s Code of Conduct, and other Company Codes of Conduct or policies and procedures that are applicable to the
Participant; or (iii) the conviction of the Participant of a felony involving moral turpitude, which are not remedied in a reasonable period of time after receipt of written notice from the Company. Notwithstanding anything in the Plan to the
contrary, forfeiture for cause may not occur following a Change of Control. 
 5.15 No Acceleration of Retirement Benefit.
Neither a Participant nor the Company may accelerate the time or schedule of any Retirement Benefit scheduled to be paid under the Plan (including, for this purpose, any Deferral Agreement or Deferral Election). Notwithstanding the foregoing, the
time or schedule of any Retirement Benefit may be accelerated in any of the following circumstances: 
 (a) Domestic Relations Orders.
The Plan Administrator may accelerate the time or schedule of a payment under the Plan to an individual other than the Participant, or a payment under the Plan may be made to an individual other than the Participant, to the extent necessary to
fulfill a domestic relations order (as defined in Section 414(p)(1)(B) of the Code); 
 (b) Payment of Employment Taxes. The Plan
Administrator may accelerate the time or schedule of a payment under the Plan, or a payment may be made under the Plan, to (x) pay the Federal Insurance Contributions Act (“FICA”) tax imposed under Sections 3101, 3121(a) or 3121(v)(2)
of the Code or (y) pay the income tax at the source on wages imposed under Section 

  

 13 

 
3401 of the Code or the corresponding withholding provisions of applicable state, local or foreign tax laws. However, the total payment under this clause
(b) may not exceed the aggregate of the FICA amount and the income tax withholding related to the FICA amount; 
 (c) Payment Upon
Income Inclusion Under Section 409A. The Plan Administrator may accelerate the time or schedule of a payment under the Plan, or a payment may be made under the Plan, at any time that the Plan fails to meet the requirements of
Section 409A of the Code and the Final Regulations. Such payment may not exceed the amount required to be included in income as a result of the failure to comply with the requirements of Section 409A of the Code and the Treasury
Regulations promulgated thereunder; or 
 (d) Certain Offsets. The Plan Administrator may accelerate the time or schedule of a payment
under the Plan, or a payment may be made under the Plan, as satisfaction of debt of the Participant to the Company, where such debt is incurred in the ordinary course of the service relationship between the Participant and the Company, the entire
amount of reduction in any of the Participant’s taxable years does not exceed $5,000, and the reduction is made at the same time and in the same amount as the debt otherwise would have been due and collected from the Participant. 
 ARTICLE VI - BENEFICIARY DESIGNATION 
 6.1 Beneficiary Designation. Each Participant shall have the right, at any time, to designate one (1) or more persons or entity as Beneficiary (both primary as well as secondary) to whom benefits under this Plan shall be
paid in the event of Participant’s death prior to complete distribution of the Participant’s vested Account balance. Each Beneficiary designation shall be in a written form prescribed by the Committee and shall be effective only when filed
with the Committee during the Participant’s lifetime. 
 6.2 Changing Beneficiary. Any Beneficiary designation may be
changed by a Participant without the consent of the previously named Beneficiary by the filing of a new Beneficiary designation with the Committee. 
 6.3 No Beneficiary Designation. If any Participant fails to designate a Beneficiary in the manner provided above, if the designation is void, or if the Beneficiary designated by a deceased Participant dies before the
Participant or before complete distribution of the Participant’s benefits, the Participant’s Beneficiary shall be the person in the first of the following classes in which there is a survivor: 
 (a) The Participant’s surviving spouse; 
 (b) The Participant’s children in equal shares, except that if any of the children predeceases the Participant but leaves surviving issue, then such issue shall take by right of representation the share the deceased child would have
taken if living; or 
 (c) The Participant’s estate. 
  

 14 

 6.4 Effect of Payment. Payment to the Beneficiary shall completely discharge the
Company’s obligations under this Plan. 
 ARTICLE VII - ADMINISTRATION 
 7.1 Committee; Duties. This Plan shall be administered by the Compensation Committee, or the Senior Vice President of Human Resources
acting as the Plan Administrator. References to the “Compensation Committee” in the Plan shall include the Senior Vice President of Human Resources acting in his capacity as Plan Administrator. The Committee or its designee shall have the
authority to make, amend, interpret and enforce all appropriate rules and regulations for the administration of the Plan and decide or resolve any and all questions, including interpretations of the Plan, as they may arise in such administration. A
majority vote of the Committee members shall control any decision. 
 7.2 Agents. The Committee may, from time to time, employ
agents and delegate to them such administrative duties as it sees fit, and may from time to time consult with counsel who may be counsel to the Company. 
 7.3 Binding Effect of Decisions. The decision or action of the Committee with respect to any question arising out of or in connection with the administration, interpretation and application of the Plan
and the rules and regulations promulgated hereunder shall be final, conclusive and binding upon all persons having any interest in the Plan. 
 7.4 Indemnity of Committee. To the fullest extent permitted by the Company’s Articles of Incorporation and By-Laws, the Company shall indemnify and hold harmless the members of the Compensation Committee or the Senior
Vice President of Human Resources acting as the Plan Administrator against any and all claims, loss, damage, expense or liability arising from any action or failure to act with respect to this Plan on account of such member’s service on the
Committee, except in the case of gross negligence or willful misconduct. 
 ARTICLE VIII - CLAIMS PROCEDURE 
 8.1 Claim. Any person or entity claiming a benefit, requesting an interpretation or ruling under the Plan (hereinafter referred to as
“Claimant”), or requesting information under the Plan shall present the request in writing to the Committee, which shall respond in writing as soon as practical, but in no event later than ninety (90) days after receiving the initial
claim (or no later than forty-five (45) days after receiving the initial claim regarding a Disability under this Plan). 
 8.2
Denial of Claim. If the claim or request is denied, the written notice of denial shall state: 
 (a) The reasons for denial,
with specific reference to the Plan provisions on which the denial is based; 
 (b) A description of any additional material or information
required and an explanation of why it is necessary, in which event the time frames listed in section 8.1 shall be one hundred and eighty (180) and seventy-five (75) days from the date of the initial claim respectively; and 
  

 15 

 (c) An explanation of the Plan’s claim review procedure. 
 8.3 Review of Claim. Any Claimant whose claim or request is denied or who has not received a response within sixty (60) days (or one
hundred and eighty (180) days in the event of a claim regarding a Disability) may request a review by notice given in writing to the Committee. Such request must be made within sixty (60) days (or one hundred and eighty (180) days in
the event of a claim regarding a Disability) after receipt by the Claimant of the written notice of denial, or in the event Claimant has not received a response sixty (60) days (or one hundred and eighty (180) days in the event of a claim
regarding a Disability) after receipt by the Committee of Claimant’s claim or request. The claim or request shall be reviewed by the Committee which may, but shall not be required to, grant the Claimant a hearing. On review, the claimant may
have representation, examine pertinent documents, and submit issues and comments in writing. 
 8.4 Final Decision. The
decision on review shall normally be made within sixty (60) days (or forty-five (45) days in the event of a claim regarding a Disability) after the Committee’s receipt of claimant’s claim or request. If an extension of time is
required for a hearing or other special circumstances, the Claimant shall be notified and the time limit shall be one hundred twenty (120) days (or ninety (90) days in the event of a claim regarding a Disability). The decision shall be in
writing and shall state the reasons and the relevant Plan provisions. All decisions on review shall be final and bind all parties concerned. 
 ARTICLE IX - AMENDMENT AND TERMINATION OF PLAN 
 9.1 Amendment. The Board may at any time amend the
Plan by written instrument, notice of which is given to all Participants and to Beneficiary receiving installment payments, except that no amendment shall reduce or otherwise adversely affect the amount accrued in any Account as of the date the
amendment is adopted. 
 9.2 Company’s Right to Terminate. The Board may at any time terminate the Plan provided that such
termination of the Plan is not treated as an “acceleration of benefits” as described in Section 409A(a)(3) of the Code and the Plan termination is identified as an exception to the “non-acceleration rule” under Treasury
Regulation Section 1.409A-3(j)(4)(ix). Upon a permitted partial or complete termination, the Board may cease all future Deferral Elections, all current Deferral Elections, and or, in its sole discretion, pay out Accounts over a period of up to
five (5) years, provided such action is not treated as an “acceleration of benefits” as described in Section 409A(a)(3) of the Code and Treasury Regulation Section 1.409A-3(j)(4)(ix). 
 ARTICLE X - MISCELLANEOUS 
 10.1 Unsecured General Creditor. Notwithstanding any other provision of this Plan, Participants and Participants’ Beneficiary shall be unsecured general creditors, with no secured or preferential rights to any assets of
Company or any other party for payment of benefits under this Plan. 

  

 16 

 
Any property held by Company for the purpose of generating the cash flow for benefit payments shall remain its general, unpledged and unrestricted assets.
Company’s obligation under the Plan shall be an unfunded and unsecured promise to pay money in the future. 
 10.2 Trust
Fund. Company shall be responsible for the payment of all benefits provided under the Plan. At its discretion, Company may establish one (1) or more rabbi trusts, with such trustees as the Board may approve, for the purpose of assisting
in the payment of such benefits. The assets of any such trust shall be held for payment of all Company’s general creditors in the event of insolvency. To the extent any benefits provided under the Plan are paid from any such trust, Company
shall have no further obligation to pay them. If not paid from the trust, such benefits shall remain the obligation of Company. 
 10.3
Nonassignability. Neither a Participant nor any other person shall have any right to commute, sell, assign, transfer, pledge, anticipate, mortgage or otherwise encumber, transfer, hypothecate or convey in advance of actual receipt the
amounts, if any, payable hereunder, or any part thereof, which are, and all rights to which are, expressly declared to be unassignable and non-transferable. No part of the amounts payable shall, prior to actual payment, be subject to seizure or
sequestration for the payment of any debts, judgments, alimony or separate maintenance owed by a Participant or any other person, nor be transferable by operation of law in the event of a Participant’s or any other person’s bankruptcy or
insolvency. 
 10.4 Not a Contract of Employment. This Plan shall not constitute an employment contract or a contract for
services of any kind between the Company and the Participant. Nothing in this Plan shall confer on the Participant the right to be retained by Company or otherwise be retained in the service of the Company or to interfere with the right of the
Company to terminate its relationship with a Participant at any time. 
 10.5 Protective Provisions. A Participant will
cooperate with Company by furnishing any and all information requested by Company, in order to facilitate the payment of benefits hereunder, and by taking such physical examinations as Company may deem necessary and taking such other action as may
be requested by Company. 
 10.6 Governing Law. The provisions of this Plan shall be construed and interpreted according to the
laws of the Commonwealth of Massachusetts, except to the extent as preempted by federal law. 
 10.7 Validity. If any provision
of this Plan shall be held illegal or invalid for any reason, said illegality or invalidity shall not affect the remaining parts hereof, but this Plan shall be construed and enforced as if such illegal and invalid provision had never been inserted
herein. 
 10.8 Notice. Any notice required or permitted under the Plan shall be sufficient if in writing and hand delivered or
sent by registered or certified mail. Such notice shall be deemed given as of the date of delivery or, if delivery is made by mail, as of the date shown on the postmark on the receipt for registration or certification. Mailed notice to the Committee
shall be directed to the company’s address. Mailed notice to a Participant or Beneficiary shall be directed to the individual’s last known address in company’s records. 
  

 17 

 10.9 Successors. The provisions of this Plan shall bind and inure to the benefit of Company
and its successors and assigns. The term successors as used herein shall include any corporate or other business entity which shall, whether by merger, consolidation, purchase or otherwise acquire all or substantially all of the business and assets
of Company, and successors of any such corporation or other business entity 
 10.10 Code Section 409A. Notwithstanding
anything herein to the contrary, in the event that the Company, upon the advice of its counsel, determines in its sole and absolute discretion that a delay in payment of a benefit hereunder or other modification is necessary to comply with
Section 409A of the Code and the Treasury Regulations promulgated thereunder, then such delay in payment or other modification shall be made. 
  

			
	HOLOGIC, INC.
		
	BY:	 	 /s/ David Brady

		 	David Brady
		 	Senior Vice President, Human Resources

  

			
	DATED:	 	December 11, 2008

  

 18

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