Document:

EX-10.5

 Exhibit 10.5 

HARMONY BIOSCIENCES HOLDINGS, INC. 

FORM OF STOCK OPTION AGREEMENT 

Harmony Biosciences Holdings, Inc., a Delaware corporation (the “Company”), is pleased to advise you, the
“Participant” whose signature appears on the signature page hereto, that the Company has granted to you a stock option (an “Option”), as provided below, under the Company’s “Harmony Biosciences Holdings,
Inc. Amended and Restated Equity Incentive Plan” (as amended from time to time, the “Plan”), a copy of which is attached hereto and incorporated herein by reference. The Option has been granted, and the shares of Common Stock
issuable upon exercise will be issued, pursuant to a “compensatory benefit plan” within the meaning of such term under Rule 701 of the Exchange Act. 

Participant
Name:                                        
                   
 Address on file
with Company 
 You have been granted an Option to purchase shares of Common Stock of the Company, subject to the terms and conditions of
the Plan and this Stock Option Agreement, as follows: 
  

					
	 Date of Grant:
	  	                                     
                   	  	
			
	 Commencement Date:
	  	                                     
                   	  	
			
	 Exercise Price per Share:
	  	$                                     
               	  	
			
	 Total # of Shares subject to Option:
	  	                                     
                   	  	
			
	 Total Exercise Price:
	  	                                     
                   	  	
			
	 Type of Option:
	  	                     Incentive Stock Option	  	
			
	 	  	                     Nonstatutory Stock Option	  	 
			
	 Expiration Date:
	  	                                     
                   	  	

 1.    Definitions. Capitalized terms used but not defined in this
Stock Option Agreement (this “Agreement”) shall have the meanings set forth in the Plan. 

2.    Option. 

(a)    This Option entitles you to purchase up to the number of shares of Common Stock set forth on the first page of this
Agreement at an exercise price per share (the “Exercise Price”) as set forth on the first page of this Agreement. Your Option shall expire at the close of business on the expiration date set forth on the first page of this Agreement
(the “Expiration Date”), subject to earlier expiration as provided in Section 3 below. Your Option is not intended to be an “incentive stock option” within the meaning of Section 422 of the
Code. 
 (b)    Payment of Option Price. Subject to Section 3 below, your Option may be
exercised in whole or in part upon payment of an amount (the “Option Price”) equal to the product of (i) the Exercise Price multiplied by (ii) the number of shares of Common Stock to be acquired, unless
otherwise determined by the Committee. Payment of the Exercise Price shall be by any of the following, or a combination of the following, at your election: (A) cash or check; (B) at the discretion of the Committee on a case by case basis,
by surrender of other shares of Common Stock of the Company that have an aggregate Fair Market Value on the date of surrender equal to the aggregate Exercise Price of the shares as to which this Option is being exercised; or (C) at the
discretion of the Committee on a case by case basis, by a cashless exercise or promissory note program approved by the Committee. 

3.    Vesting; Expiration; Exercisability. 

(a)    Vesting. Your Option may be exercised only to the extent it has become vested. Subject to your continued
employment or engagement by the Company or an Affiliate on each applicable vesting date, and except as may otherwise be provided herein or in the Plan, twenty percent (20%) of the Option shall become vested on the first anniversary of the
Commencement Date (the “First Vesting Date”), and the remaining eighty percent (80%) shall become vested ratably on each of the subsequent four anniversaries following the First Vesting Date. The Option shall not vest at any
time after the termination of your employment or engagement with the Company. 
 (b)    Change in Control.
Notwithstanding anything to the contrary herein, upon the occurrence of a Change in Control, and irrespective of whether outstanding Options are being assumed, substituted, exchanged or terminated in connection with the transaction, the vesting of
your Option shall accelerate such that all unvested Options shall become exercisable and vested to the extent not then otherwise vested. The portion of your Option that has not yet become vested shall become vested as provided herein due to a Change
in Control if and only if, as of the date of the consummation of such Change in Control, you remain employed or engaged by the Company or an Affiliate from the Commencement Date through and including such Change in Control. In any event, any
portion of your Option which has not been exercised prior to or in connection with the Change in Control shall expire and be forfeited for no consideration, unless otherwise determined by the Committee. 

(c)    Expiration of Option. In no event shall any part of your Option be exercisable after the Expiration Date.

 (d)    Early Expiration upon Termination of Employment. Except as otherwise provided in Section 4(a)(iii)
of the Plan, any portion of your Option that was not vested and exercisable as of the date on which your employment or service with the Company or an Affiliate terminates shall expire and be forfeited on such date, and any portion of your Option
that was vested and exercisable as of such termination date shall also expire and be forfeited as of such termination date. 

  
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 (e)    Procedure for Exercise. You may exercise all or any
portion of your Option, to the extent it has vested and is exercisable, at any time and from time to time prior to its expiration, by delivering to the Company’s Corporate Secretary an Exercise Notice in the form attached to this Agreement as
Exhibit A, and a duly executed joinder, in form and content acceptable to the Company, to all or portions of any stockholders, financing, or other agreement as determined by the Committee, together with payment of the Option Price in
accordance with the provisions of Section 2(b) above. As a condition to any exercise of your Option, you shall make all customary investment representations which the Company requires. The Company is not obligated, and will
have no liability for failure, to issue or deliver any shares of Common Stock upon exercise of this Option unless such issuance or delivery would comply with applicable laws, with such compliance determined by the Company in consultation with its
legal counsel. As a condition to the exercise of your Option, and as further set forth in Section 6 of this Agreement, you agree to make adequate provision, acceptable to the Company, for federal, state, local and
non-U.S. income an employment tax withholding obligations, if any, which arise upon the grant, vesting or exercise of this Option, or disposition of shares of Common Stock acquired upon exercise of this
Option, whether by withholding, direct payment to the Company, or otherwise. Further, if you (or any other person) is exercising this Option in connection with or following the Company’s termination of your employment or engagement with the
Company or an Affiliate, as a condition to exercise of your Option and the issuance of shares of Common Stock hereunder, you shall execute and deliver to the Company a general release of claims with respect to the termination of your employment or
engagement with the Company or any Affiliate in form and substance provided to you by the Company at that time. 

4.    Conformity with Plan. Your Option is intended to conform in all respects with, and is subject to all
applicable provisions of, the Plan (which is incorporated herein by reference). Inconsistencies between this Option and the Plan shall be resolved in accordance with the terms of the Plan. By executing and returning the enclosed copy of this Option,
you acknowledge your receipt of this Option and the Plan and agree to be bound by all of the terms of this Option and the Plan. 

5.    Rights of Participants. Nothing in this Option shall interfere with or limit in any way the right of the
Company or any of its Affiliates to terminate your employment or engagement at any time (with or without Cause), nor confer upon you any right to continue to be employed or engaged by the Company or any Affiliate for any period of time or to
continue your present (or any other) rate of compensation or benefits. In the event of any termination of your employment or engagement with the Company or an Affiliate (including any termination of your employment or engagement by the Company or an
Affiliate without Cause), any portion of your Option that was not previously vested and exercisable shall expire and be forfeited, except as otherwise provided herein or in the Plan. Nothing in this Option shall confer upon you any right to be
selected again as a participant under the Plan, and nothing in the Plan or this Option shall provide for any adjustment to the number of shares of Common Stock subject to your Option upon the occurrence of subsequent events, except as provided in
Section 7 or the Plan. Also, to the extent applicable, the Exercise Price has been set in good faith compliance with the applicable guidance issued by the IRS under Section 409A of the Internal Revenue Code of 1986, as amended. However,
there is no guarantee that the IRS will agree with the valuation, and by signing below, you agree and acknowledge that the Company shall not be held liable for any applicable costs, taxes or penalties associated with this Option if, in fact, the IRS
were to determine that this Option constitutes deferred compensation under Section 409A of the Code. You should consult with your own tax advisor concerning the tax consequences of such a determination by the IRS. 

6.    Withholding of Taxes. The Company shall be entitled, if necessary or desirable, to deduct and withhold from
you, from any amounts due and payable by the Company to you (or secure payment from you in lieu of withholding), the amount of any withholding or other tax due in connection with the issuance, vesting, ownership, modification, adjustment,
disposition, exercise or otherwise with respect to your Option or the securities issuable under your Option, and the Company may defer the issuance 

  
 3 

 
of shares of Common Stock under your Option unless you make arrangements satisfactory to the Company for your payment of such amounts or indemnification of the Company with respect to such
matters. In the event that the Company does not make such deductions or withholdings, you shall indemnify the Company for and remain responsible for any amounts paid or payable by the Company with respect to any such taxes, together with any
interest, penalties and additions to tax and any related expenses thereto. 
 7.    Adjustments. In the event of
a reorganization, recapitalization, stock dividend or stock split, or combination or other change in the shares of Common Stock, the Committee shall make such adjustments in the number and type of securities authorized by the Plan, the number
and type of securities covered by your Option and the Exercise Price specified herein as the Committee may determine to be appropriate and equitable. 

8.    Miscellaneous. 

(a)    Amendment. Except as otherwise provided herein, any provision of this Agreement may be amended or waived
only with the prior written consent of you and the Company. This Agreement may also be amended as provided under the Plan, but no such amendment shall adversely effect your rights under this Agreement without your written consent, unless otherwise
permitted by the Plan. 
 (b)    Successors and Assigns. Except as otherwise expressly provided herein, all
covenants and agreements contained in this Agreement by or on behalf of any of the parties hereto shall bind and inure to the benefit of the respective successors and permitted assigns of the parties hereto whether so expressed or not. 

(c)    Severability. Whenever possible, each provision of this Agreement shall be interpreted in such manner as to
be effective and valid under applicable law, but if any provision of this Agreement is held to be prohibited by or invalid under applicable law, such provision shall be ineffective only to the extent of such prohibition or invalidity, without
invalidating the remainder of this Agreement. 
 (d)    Counterparts and Delivery by Facsimile or Email. This
Agreement and any agreement or instrument entered into in connection with this Agreement, and any amendments hereto or thereto, may be executed in separate counterparts, each of which is deemed to be an original and all of which taken together
constitute one and the same agreement, and, to the extent signed and delivered by means of a facsimile machine or email (including by an attachment thereto (e.g., PDF)), shall be treated in all manner and respects as an original agreement or
instrument and shall be considered to have the same binding legal effect as if it were the original signed version thereof delivered in person. At the request of any party hereto or to any such agreement or instrument, each other party hereto or
thereto shall re-execute original forms thereof and deliver them to all other parties. No party hereto or to any such agreement or instrument shall raise the use of a facsimile machine or email (including by
an attachment thereto (e.g., PDF)) to deliver a signature or the fact that any signature or agreement or instrument was transmitted or communicated through the use of a facsimile machine or by email as a defense to the formation of a contract and
each such party forever waives any such defense. 
 (e)    No Strict Construction. The language used in this
Agreement shall be deemed to be the language chosen by the parties hereto to express their mutual intent, and no rule of strict construction shall be applied against any party. 

(f)    Construction; Determinations. This Agreement is granted pursuant to the Plan and is, in all respects,
limited by and subject to the express provisions of the Plan, as amended from time to time. The interpretation and construction by the Committee of the Plan, this Agreement and any such rules and regulations adopted by the Committee for purposes of
administering the Plan, shall be final, conclusive 

  
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and binding upon you and all other Persons. The descriptive headings of the sections of this Agreement are for convenience only and do not constitute a part of this Agreement. The definitions of
terms herein shall apply equally to the singular and plural forms of the terms defined. Whenever the context may require, any pronoun shall include the corresponding masculine, feminine and neuter for Ms. The words “include”,
“includes” and “including” shall be deemed to be followed by the phrase “without limitation”. Unless the context requires otherwise (i) any definition of or reference to any agreement, instrument or other document
herein shall be construed as referring to such agreement, instrument or other document as from time to time amended, supplemented or otherwise modified (subject to any restrictions on such amendments, supplements or modifications set forth herein),
(ii) any reference herein to any Person shall be construed to include such Person’s successors and assigns, (iii) the words “herein”, “hereof” and “hereunder”, and words of similar import, shall be construed
to refer to this Agreement in its entirety and not to any particular provision hereof and (iv) all references herein to sections shall be construed to refer to sections of this Agreement unless otherwise noted. 

(g)    Governing Law. Any issues, disputes or claims arising out of or in connection with this Agreement and all
issues and questions concerning the construction, validity, enforcement and interpretation of this Agreement shall be governed by and construed in accordance with the laws of the State of Delaware, without giving effect to any choice of law or
conflict of law rules or provisions (whether of the State of Delaware or any other jurisdiction) that would cause the application of the laws of any jurisdiction other than the State of Delaware.  

(h)    Notices. Any communication or notice required or permitted to be given hereunder shall be in writing, and,
if to the Company, to its principal place of business, attention: Chief Executive Officer, and, if to you, to the address appearing on the records of the Company. Such communication or notice shall be delivered personally or by a reputable overnight
delivery service. Any such notice shall be deemed given when received by the intended recipient. Notwithstanding the foregoing, any notice required or permitted hereunder from the Company to you may be made by electronic means, including by
electronic mail to your Company-maintained electronic mailbox, and you hereby consent to receive such notice by electronic delivery. To the extent permitted in an electronically delivered notice described in the previous sentence, you shall be
permitted to respond to such notice or communication by way of a responsive electronic communication, including by electronic mail. 

(i)    Waiver of Section 220 of the DGCL. You acknowledge and understand that, but for the
waiver made herein, you would be entitled, upon written demand under oath stating the purpose thereof, to inspect for any proper purpose, and to make copies and extracts from, the Company’s stock ledger, a list of its stockholders, and its
other books and records, and the books and records of subsidiaries of the Company, if any, under the circumstances and in the manner provided in Section 220 of the General Corporation Law of Delaware (any and all such rights, and any and all
such other rights of yours as may be provided for in Section 220, the “Inspection Rights”). In light of the foregoing, until the first sale of Common Stock of the Company to the general public pursuant to a registration
statement filed with and declared effective by the Securities and Exchange Commission under the Exchange Act, you hereby unconditionally and irrevocably waive the Inspection Rights, whether such Inspection Rights would be exercised or pursued
directly or indirectly pursuant to Section 220 or otherwise, and covenants and agrees never to directly or indirectly commence, voluntarily aid in any way, prosecute, assign, transfer, or cause to be commenced any claim, action, cause of
action, or other proceeding to pursue or exercise the Inspection Rights. 
 (j)    Restrictive Covenants. As a
condition to this Agreement and to eligibility, receipt or retention of the payments, rights and benefits in respect of the Options awarded hereunder, you agree to those additional terms set forth on Exhibit B, which are hereby incorporated
by reference and which shall survive termination of your service or employment with the Company or any Affiliates 

  
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 (k)    WAIVER OF JURY TRIAL; JURISDICTION. NO PARTY TO THIS
AGREEMENT OR ANY ASSIGNEE, SUCCESSOR, HEIR OR PERSONAL REPRESENTATIVE OF A PARTY SHALL SEEK A JURY TRIAL IN ANY LAWSUIT, PROCEEDING, COUNTERCLAIM OR ANY OTHER LITIGATION PROCEDURE BASED UPON OR ARISING OUT OF THIS AGREEMENT OR ANY OF THE OTHER
AGREEMENTS OR THE DEALINGS OR THE RELATIONSHIP BETWEEN THE PARTIES. NO PARTY WILL SEEK TO CONSOLIDATE ANY SUCH ACTION, IN WHICH A JURY TRIAL HAS BEEN WAIVED, WITH ANY OTHER ACTION IN WHICH A JURY TRIAL CANNOT OR HAS NOT BEEN WAIVED. THE PROVISIONS
OF THIS PARAGRAPH HAVE BEEN FULLY DISCUSSED BY THE PARTIES HERETO, AND THESE PROVISIONS SHALL BE SUBJECT TO NO EXCEPTIONS. THE PARTIES AGREE THAT ANY ACTIONS OR PROCEEDINGS ARISING IN CONNECTION WITH THIS AGREEMENT SHALL BE TRIED AND LITIGATED
EXCLUSIVELY IN THE FEDERAL OR STATE COURTS LOCATED IN COOK COUNTY, ILLINOIS. NEITHER PARTY HAS IN ANY WAY AGREED WITH OR REPRESENTED TO ANY OTHER PARTY THAT THE PROVISIONS OF THIS PARAGRAPH WILL NOT BE FULLY ENFORCED IN ALL INSTANCES. 

(l)    Entire Agreement. This Agreement and the Plan constitute the entire understanding between you and the
Company and supersede all other agreements, whether written or oral, with respect to the acquisition by you of Common Stock of the Company. 

*    *    *    *    * 

  
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 Please execute the extra copy of this Agreement in the space below and return it to the
Company’s at its executive offices to confirm your understanding and acceptance of the agreements contained in this Agreement. 
  

			
	 Very truly yours,

	
	HARMONY BIOSCIENCES HOLDINGS, INC.

 
			
		
	By:	 	  

 
			
		
	Its:	 	 General Counsel

 The undersigned hereby acknowledges having read this Agreement and the Plan and hereby agrees to be
bound by all provisions set forth herein and in the Plan. 
  

			
	PARTICIPANT
	
	  

			
	Name:	 	  

 EXHIBIT A 

OPTION EXERCISE NOTICE 
 The
undersigned is the holder of an option (the “Option”) to acquire [number of options in grant] shares of Common Stock in Harmony Biosciences Holdings, Inc. (the “Company”) granted pursuant to that certain Stock
Option Agreement, dated as of [Grant Date] (the “Stock Option Agreement”). Capitalized terms used and not otherwise defined in this option exercise notice shall have the meaning given to such terms in the Plan. Subject to the
further conditions of Section 3(d) of the Stock Option Agreement, the undersigned hereby exercises the Option with respect to                  shares of
Common Stock for an aggregate exercise price of $_______, payable in accordance Section 2(b) of the Stock Option Agreement. 
 In
connection with the foregoing exercise of the Option, the undersigned represents and acknowledges to the Company as follows: 
  

	1)	 He or she has received a copy of the Plan and has read and understands the Plan. 

 

	2)	 He or she has executed a joinder to all stockholders, financing, and related agreements provided by the
Company. 

  

	3)	 The shares of Common Stock are subject to transfer restrictions set forth in one or more stockholders’
agreements and are subject to repurchase pursuant to the terms of the Stock Option Agreement and/or Plan. 

  

	4)	 The shares of Common Stock have not been registered under the Exchange Act and are offered pursuant to an
exemption thereunder and that such shares of Common Stock have not been approved or disapproved by the Securities and Exchange Commission or by any other Federal or state agency. 

 

	5)	 The shares of Common Stock acquired upon exercise of the Option are being acquired for investment purposes, and
not on behalf or for the benefit of any other person, trust, estate or business organization, and the undersigned has no intention of distributing any shares of Common Stock to others in violation of the Exchange Act. 

 

	6)	 There are no existing circumstances which will compel the undersigned to obtain money by the sale of any shares
of Common Stock, and the undersigned has no reason to anticipate any change in such undersigned’s circumstances, financial or otherwise, or to anticipate any occasion or event, which would cause the undersigned to assign, transfer, sell or
distribute, or necessitate or require the undersigned to assign, transfer, sell or distribute, any shares of Common Stock. The undersigned understands that the shares of Common Stock are illiquid and that the undersigned may be required to hold the
shares of Common Stock indefinitely. 

  

	7)	 The shares of Common Stock may also be subject to resale restrictions imposed by the securities laws of various
states and may not be sold without compliance with such laws. 

  

	8)	 The undersigned is a resident of the State of [name of State]. 

 

	9)	 The undersigned is responsible for the tax consequences relating to the exercise of the Option.

  

			
	 Executed this date
of                                        
          
	  	
                      
                                         
                     

	 	  	 [participant name]

  
 8 

 EXHIBIT B 

ADDITIONAL TERMS 

(a)    Acknowledgements. Capitalized terms used in this Exhibit B and not elsewhere defined in the Agreement
to which this Exhibit B is attached shall have the meanings set forth in paragraph (j) of this Exhibit B. This Exhibit B is intended to apply in addition to and not in lieu of any similar covenant or term in
Participant’s employment or services agreement, offer letter or similar document or other arrangement with the Company or any of its Affiliates (the Company and its Affiliates are collectively referred to herein, the “Company
Group”), and by signing the Agreement Participant acknowledges and agrees to same. Participant acknowledges that the Participant has been advised by the Company that the restrictions and covenants contained in this Exhibit B, and the
Participant’s agreement to such restrictions and covenants, constitute a material inducement to the Company to execute the Agreement, to provide the Participant with the Shares pursuant to the Agreement to which this Exhibit is attached. The
Participant acknowledges that participation in the Plan and eligibility for such Shares constitutes sufficient consideration for the promises and agreements made by the Participant hereunder, which shall survive the termination of the
Participant’s employment or service with the Company Group. The Participant acknowledges that: (i) as a result of the Participant’s employment or service with the Company Group, the Participant has obtained and will continue to obtain
Confidential Information; (ii) the Confidential Information, and each element or aspect thereof, has been developed and created by the Company Group at substantial time and expense; (iii) the Confidential Information constitutes valuable
proprietary assets of the Company Group, the Company Group’s reservation of rights and control of Confidential Information is of significant competitive importance and commercial value to the Company Group, and the Company Group will suffer
substantial damage and irreparable harm which will be difficult to compute if, during the period of employment or service or thereafter, the Participant discloses or improperly uses any such Confidential Information in violation of the provisions of
this Exhibit B; (iv) the nature of the Company Group’s business is such that it is highly competitive and could be conducted anywhere in the world and is not limited to any particular geographic scope or region(s); (v) the Company
Group will suffer substantial damage and irreparable harm which will be difficult to compute if, during the period of employment or service or thereafter, the Participant should solicit or interfere with any individual employed by or providing
services to any of the Company Group or their investment opportunities, acquisition targets, financing sources, suppliers or customers in violation of this Exhibit B; (vi) the provisions of this Exhibit B are reasonable and
necessary for the protection of the legitimate business interests of the Company Group; (vii) the provisions of this Exhibit B will not preclude the Participant from other gainful employment or service following the termination of his or
her services to the Company Group; (viii) the Confidential Information constitutes a protectable business interest of the Company Group; (ix) that Confidential Information is vital, sensitive, confidential and proprietary to the Company
Group; and (x) a breach by the Participant of this Exhibit B would result in losses to the Company Group for which remedies at law are inadequate, and would result in the expenditure of additional financial costs, loss of business
advantage and opportunities, potential liability under confidentiality obligations with third parties and potential civil and criminal penalties. 

(b)    Obligation to Maintain Confidentiality. The Participant acknowledges that the information, observations and
data obtained by him during the course of his service with the Company concerning the business and affairs of the Company Group, including, but not limited to, information concerning acquisition opportunities in or reasonably related to the business
of the Company Group (“Confidential Information”), of which Participant becomes aware during the Participant’s service with the Company are the property of the Company Group. Therefore, Participant agrees that he will not
disclose to any unauthorized Person or use for his own account any Confidential Information without the Board’s written consent, unless and to the extent that the aforementioned matters (i) become generally known to and available for use
by the public other than as a result of Participant’s acts or omissions in breach of this Agreement, (ii) were known by Participant prior to his commencement of service with the Company (other than Confidential Information disclosed to
Participant in confidence in connection with Participant’s employment with Company or another member of the Company Group), or (iii) is required to be disclosed pursuant to any applicable law or court order. Participant agrees to deliver
to Company upon Participant’s termination of service with the Company, or at any other time Company may request in writing, all memoranda, 

  
 9 

 
notes, plans, records, reports and other documents (and copies thereof) relating to the business of the Company Group (including, without limitation, all acquisition prospects, lists and contact
information) or containing Confidential Information which he may then possess or have under his control. 

(c)    Third Party Information. Participant understands that the Company Group will receive from third parties
confidential or proprietary information (“Third Party Information”) subject to a duty on the part of the Company Group to maintain the confidentiality of such information and to use it only for certain limited purposes. Participant
will hold Third Party Information in strictest confidence and will not disclose to anyone (other than personnel, consultants, attorneys, accountants and other advisors of the Company Group who need to know such information in connection with their
work for the Company Group) or use such Third Party Information, except to the extent that (i) such Third Party Information shall have become generally known to and available for use by the public other than as a result of Participant’s
acts or omissions in breach of this Agreement, (ii) such Third Party Information is required to be disclosed pursuant to any applicable law or court order, or (iii) the disclosure of such Third Party Information is expressly authorized by
the Board in writing. 
 (d)    Noncompetition and Nonsolicitation. Participant acknowledges that in the
course of his service with Company he will become familiar with trade secrets and other confidential information concerning the Company Group and that his services will be of special, unique and extraordinary value to Company. Therefore, Participant
agrees that: 
 (i)    Noncompetition. For a period of one year following the Participant’s service with the
Company Group, Participant shall not, anywhere in the world, directly or indirectly own, manage, control, participate in, consult with, render services for, or in any manner engage in any business that is a Competing Business as of the relevant date
of determination. 
 (ii)    Nonsolicitation. For a period of one year following the Participant’s service
with the Company Group, Participant shall not, other than in the good faith performance of his duties for the Company Group, directly or indirectly through another entity induce or attempt to induce any employee of the Company Group to leave the
employ of any member of the Company Group. 
 (e)    Relief. The Participant further acknowledges that the
Company Group are third party beneficiaries of the Agreement and this Exhibit B and will be irreparably harmed if such covenants are not specifically enforced. Accordingly, Participant agrees that in addition to any other relief to which the
Company Group may be entitled, in law or equity, they shall be entitled to obtain injunctive relief (without the requirement of posting a bond or other security) from a court of competent jurisdiction, for the purpose of restraining the Participant
from an actual or threatened breach of any such covenants. Participant also acknowledges that the remedies afforded pursuant to this paragraph (i) are not exclusive, nor shall they preclude any member of the Company Group from seeking or
receiving any other relief, including without limitation, any form of monetary or other equitable relief. Upon the reasonable request by any member of the Company Group, the Participant shall provide reasonable assurances and evidence of compliance
with the terms of this Exhibit B. In the event that injunctive relief or specific enforcement of the Participant’s obligations hereunder is required, the Participant will (i) indemnify and hold the Company Group harmless with
respect to any damages (whether actual or otherwise), actions, losses, costs and liabilities arising from the Participant’s breach of the Participant’s obligations under the Agreement or this Exhibit B, including providing an
accounting (and provide such information as is reasonably necessary for the Company to create or confirm such accounting) and disgorging any profits, gains or other windfalls resulting directly or indirectly from such breach, and (ii) reimburse
or pay on demand the Company Group, as applicable, for fees and costs incurred by them (including, without limitation, reasonable attorneys’ fees and costs) in obtaining such injunctive relief or specific enforcement and/or in seeking such
damages. 

  
 10 

 (j)     Definitions. For purposes of this Exhibit B, the
following definitions are applicable: 
 “Business” means, at the relevant time, the licensing, acquisition, development,
commercialization, distribution and lifecycle management of pharmaceutical products in those therapeutic areas in which the Company Group is materially engaged. 

“Competing Business” means any business that competes with the Business. 

(k)    Judicial Modification. If any court shall deem any of the provisions of the Agreement or this Exhibit
B invalid or unenforceable under any applicable law, by reason of being vague or unreasonable as to area, duration or scope of activity, it is the parties’ intentions and desire that such court shall have the authority to modify the
Agreement and this Exhibit B and will so modify such Agreement and this Exhibit B in a manner so as to render it enforceable while maintaining the original intent thereof to the maximum extent possible. In the event of such
modification, the Participant and the Company agrees that this Agreement and Exhibit B, as so amended, shall be valid and binding as though any invalid or unenforceable provision never had been included herein. 

(l)     Severability. If any term or provision shall be held invalid or unenforceable, the remaining terms and
provisions hereof shall not be affected thereby, unless such a construction would be unreasonable. 
 *** 

  
 11EX-10.6

 Exhibit 10.6 

HARMONY BIOSCIENCES HOLDINGS, INC. 

2020 INCENTIVE AWARD PLAN 

RESTRICTED STOCK UNIT GRANT NOTICE 

Harmony Biosciences Holdings, Inc., a Delaware corporation (the “Company”), has granted to the participant listed
below (“Participant”) the Restricted Stock Units (the “RSUs”) described in this Restricted Stock Unit Grant Notice (this “Grant Notice”), subject to the terms and conditions of
the Harmony Biosciences Holdings, Inc. 2020 Incentive Award Plan (as amended from time to time, the “Plan”) and the Restricted Stock Unit Agreement attached hereto as Exhibit A (the
“Agreement”), both of which are incorporated into this Grant Notice by reference. Capitalized terms not specifically defined in this Grant Notice or the Agreement have the meanings given to them in the Plan. 

 

			
	 Participant:
	  	
		
	 Grant Date:
	  	
		
	 Number of RSUs:
	  	
		
	 Vesting Commencement Date:
	  	
		
	 Vesting Schedule:
	  	 [To be specified]

 By accepting (whether in writing, electronically or otherwise) the RSUs, Participant agrees to be bound by the
terms of this Grant Notice, the Plan and the Agreement. Participant has reviewed the Plan, this Grant Notice and the Agreement in their entirety, has had an opportunity to obtain the advice of counsel prior to executing this Grant Notice and fully
understands all provisions of the Plan, this Grant Notice and the Agreement. Participant hereby agrees to accept as binding, conclusive and final all decisions or interpretations of the Administrator upon any questions arising under the Plan, this
Grant Notice or the Agreement. 
  

			
	 HARMONY BIOSCIENCES HOLDINGS, INC. 
	  	 PARTICIPANT

		
	By:                                     
                                         
       	  	                                     
                                         
              
		
	Name:                                     
                                         
   	  	 [Participant Name]

		
	Title:                                     
                                         
    	  	

 Exhibit A 

RESTRICTED STOCK UNIT AGREEMENT 

Capitalized terms not specifically defined in this Restricted Stock Unit Agreement (this “Agreement”) have the
meanings specified in the Grant Notice or, if not defined in the Grant Notice, in the Plan. 
 ARTICLE I. 

GENERAL 

1.1    Award of RSUs. The Company has granted the RSUs to Participant effective as of the Grant Date set forth in
the Grant Notice (the “Grant Date”). Each RSU represents the right to receive one Share as set forth in this Agreement. Participant will have no right to the distribution of any Shares until the time (if ever) the RSUs have
vested. 
 1.2    Incorporation of Terms of Plan. The RSUs are subject to the terms and conditions set forth in
this Agreement and the Plan, which is incorporated herein by reference. In the event of any inconsistency between the Plan and this Agreement, the terms of the Plan will control. 

1.3    Unsecured Promise. The RSUs will at all times prior to settlement represent an unsecured Company obligation
payable only from the Company’s general assets. 
 ARTICLE II. 

VESTING; FORFEITURE AND SETTLEMENT 

2.1    Vesting; Forfeiture. The RSUs will vest according to the vesting schedule in the Grant Notice except that
any fraction of an RSU that would otherwise be vested will be accumulated and will vest only when a whole RSU has accumulated. In the event of Participant’s Termination of Service for any reason, all unvested RSUs will immediately and
automatically be cancelled and forfeited, except as otherwise determined by the Administrator or provided in a binding written agreement between Participant and the Company. 

2.2    Settlement. 

(a)    The RSUs will be paid in Shares as soon as administratively practicable after the vesting of the applicable RSU,
but in no event later than March 15 of the year following the year in which the RSU’s vesting date occurs. 

(b)    Notwithstanding the foregoing, the Company may delay any payment under this Agreement that the Company reasonably
determines would violate Applicable Law until the earliest date the Company reasonably determines the making of the payment will not cause such a violation (in accordance with Treasury Regulation
Section 1.409A-2(b)(7)(ii)); provided the Company reasonably believes the delay will not result in the imposition of excise taxes under Section 409A. 

ARTICLE III. 
 TAXATION
AND TAX WITHHOLDING 
 3.1    Representation. Participant represents to the Company that Participant has
reviewed with Participant’s own tax advisors the tax consequences of this Award and the transactions contemplated by the Grant Notice and this Agreement. Participant is relying solely on such advisors and not on any statements or
representations of the Company or any of its agents. 

  
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 3.2    Tax Withholding. 

(a)    Unless the Administrator otherwise determines, the Company shall withhold, or cause to be withheld, Shares
otherwise vesting or issuable under this Award (including the RSUs) in satisfaction of any applicable withholding tax obligations. The number of Shares which may be so withheld or surrendered shall be limited to the number of Shares which have a
Fair Market Value on the date of withholding no greater than the aggregate amount of such liabilities based on the maximum individual statutory withholding rates in Participant’s applicable jurisdictions for federal, state, local and foreign
income tax and payroll tax purposes that are applicable to such taxable income. 
 (b)    Participant acknowledges that
Participant is ultimately liable and responsible for all taxes owed in connection with the RSUs, regardless of any action the Company or any Subsidiary takes with respect to any tax withholding obligations that arise in connection with the RSUs.
Neither the Company nor any Subsidiary makes any representation or undertaking regarding the treatment of any tax withholding in connection with the awarding, vesting or payment of the RSUs or the subsequent sale of Shares. The Company and its
Subsidiaries do not commit and are under no obligation to structure the RSUs to reduce or eliminate Participant’s tax liability. 

ARTICLE IV. 
 OTHER
PROVISIONS 
 4.1    Adjustments. Participant acknowledges that the RSUs and the Shares subject to the RSUs
are subject to adjustment, modification and termination in certain events as provided in this Agreement and the Plan. 

4.2    Notices. Any notice to be given under the terms of this Agreement to the Company must be in writing and
addressed to the Company in care of the Company’s Secretary at the Company’s principal office or the Secretary’s then-current email address or facsimile number. Any notice to be given under the terms of this Agreement to Participant
must be in writing and addressed to Participant (or, if Participant is then deceased, to the Designated Beneficiary) at Participant’s last known mailing address, email address or facsimile number in the Company’s personnel files. By a
notice given pursuant to this Section, either party may designate a different address for notices to be given to that party. Any notice will be deemed duly given when actually received, when sent by email, when sent by certified mail (return receipt
requested) and deposited with postage prepaid in a post office or branch post office regularly maintained by the United States Postal Service, when delivered by a nationally recognized express shipping company or upon receipt of a facsimile
transmission confirmation. 
 4.3    Titles. Titles are provided herein for convenience only and are not to serve
as a basis for interpretation or construction of this Agreement. 
 4.4    Conformity to Securities Laws.
Participant acknowledges that the Plan, the Grant Notice and this Agreement are intended to conform to the extent necessary with all Applicable Laws and, to the extent Applicable Laws permit, will be deemed amended as necessary to conform to
Applicable Laws. 
 4.5    Successors and Assigns. The Company may assign any of its rights under this Agreement
to single or multiple assignees, and this Agreement will inure to the benefit of the successors and assigns of the Company. Subject to the restrictions on transfer set forth in this Agreement or the Plan, this Agreement will be binding upon and
inure to the benefit of the heirs, legatees, legal representatives, successors and assigns of the parties hereto. 

  
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 4.6    Limitations Applicable to Section 16
Persons. Notwithstanding any other provision of the Plan or this Agreement, if Participant is subject to Section 16 of the Exchange Act, the Plan, the Grant Notice, this Agreement and the RSUs will be subject to any additional limitations
set forth in any applicable exemptive rule under Section 16 of the Exchange Act (including any amendment to Rule 16b-3) that are requirements for the application of such exemptive rule. To the extent
Applicable Laws permit, this Agreement will be deemed amended as necessary to conform to such applicable exemptive rule. 

4.7    Entire Agreement. The Plan, the Grant Notice and this Agreement (including any exhibit hereto) constitute
the entire agreement of the parties and supersede in their entirety all prior undertakings and agreements of the Company and Participant with respect to the subject matter hereof. 

4.8    Agreement Severable. In the event that any provision of the Grant Notice or this Agreement is held illegal
or invalid, the provision will be severable from, and the illegality or invalidity of the provision will not be construed to have any effect on, the remaining provisions of the Grant Notice or this Agreement. 

4.9    Limitation on Participant’s Rights. Participation in the Plan confers no rights or interests other than
as herein provided. This Agreement creates only a contractual obligation on the part of the Company as to amounts payable and may not be construed as creating a trust. Neither the Plan nor any underlying program, in and of itself, has any assets.
Participant will have only the rights of a general unsecured creditor of the Company with respect to amounts credited and benefits payable, if any, with respect to the RSUs, and rights no greater than the right to receive cash or the Shares as a
general unsecured creditor with respect to the RSUs, as and when settled pursuant to the terms of this Agreement. 

4.10    Not a Contract of Employment. Nothing in the Plan, the Grant Notice or this Agreement confers upon
Participant any right to continue in the employ or service of the Company or any Subsidiary or interferes with or restricts in any way the rights of the Company and its Subsidiaries, which rights are hereby expressly reserved, to discharge or
terminate the services of Participant at any time for any reason whatsoever, with or without cause, except to the extent expressly provided otherwise in a written agreement between the Company or a Subsidiary and Participant. 

4.11    Counterparts. The Grant Notice may be executed in one or more counterparts, including by way of any
electronic signature, subject to Applicable Law, each of which will be deemed an original and all of which together will constitute one instrument. 

* * * * * 

  
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