Document:

Exhibit 10.22

Exhibit 10.22

SEVENTH AMENDMENT TO LEASE

THIS SEVENTH AMENDMENT TO LEASE (“Amendment”) made as of the 17th day of November, 2008, by
and between 111 BARCLAY ASSOCIATES (“Landlord”), sole beneficiary under CHICAGO TITLE LAND TRUST
COMPANY, as successor trustee to LASALLE BANK NATIONAL ASSOCIATION, as successor trustee
(“Trustee”) to AMERICAN NATIONAL BANK AND TRUST COMPANY OF CHICAGO, as Trustee under Trust
Agreement (“Trust”) dated January 1, 1991 and known as Trust No. 113370-03 (“Landlord”) and
BIOSANTE PHARMACEUTICALS, INC. (“Tenant”).

RECITALS:

WHEREAS, Landlord and Tenant entered into that certain Lease dated December 19, 2003, as
amended by First Amendment to Lease dated February 26, 2004, as modified by Letter Amendment dated
March 19, 2004, as amended by Second Amendment to Lease dated January 4, 2005, as amended by Third
Amendment to Lease dated January 27, 2006, as amended by Fourth Amendment to Lease dated March 7,
2007, as amended by Fifth Amendment to Lease dated November 2, 2007, and as amended by Sixth
Amendment to Lease dated April 18, 2008, (the original lease, as amended, the “Existing Lease”, and
the Existing Lease as amended by this Amendment, the “Lease”) which Lease demised to Tenant a
portion of the 2nd floor known as Suite 280 and Suite 220 (“Premises”) of the building
known as 111 Barclay Boulevard, Lincolnshire, Illinois (“Building”); and

WHEREAS, Tenant desires to exercise its right to extend the Term of the Lease for the entire
Premises in accordance with Paragraph 7 of the Sixth Amendment to the Lease, and the Landlord and
Tenant desire to amend the Existing Lease to reflect the Tenant’s exercise of such right and to
modify the Existing Lease in certain other respects.

NOW, THEREFORE, in consideration of the mutual covenants and conditions contained herein, the
Lease is hereby further amended as follows:

1. Recitals. The Recitals are true and correct in all material respects and are
incorporated as if fully set forth herein.

2. Defined Terms. Capitalized terms used but not defined herein shall have the
meaning assigned to them in the Existing Lease.

3. First Extended Term. The Term of the Lease is hereby extended for a period of
twelve (12) months (“First Extended Term”) commencing on May 1, 2009, and ending on April 30, 2010
(the “Expiration Date”). The First Extended Term shall be upon all of the agreements, terms,
covenants and conditions of the Existing Lease binding upon Tenant, as the same are modified by
this Amendment. Upon execution and delivery of this Amendment (i) the First Extended Term shall be
added to and become part of the Term (but shall not be considered part of the initial Term); (ii)
any reference to “this Lease”, to the “Term”, the “term of the Lease” or any similar expression
shall be deemed to include the First Extended Term; (iii) Tenant shall occupy the Premises in its
“AS-IS” condition during the First Extended Term, and Landlord will not be required to perform any
improvements to the Premises to prepare it for Tenant’s continued occupancy during the First
Extended Term, nor will Landlord be required to provide Tenant with
any allowance for the performance of such improvements; and (iv) the Term shall end on the
Expiration Date unless earlier terminated pursuant to the terms and conditions hereof. Tenant will
pay Base Rent during the First Extended Term in accordance with Section 1 of the Lease at the rate
of $13,750.00 per month.

 

 

 

4. Second Extended Term. Tenant’s option to extend the term of the Lease as provided
in Paragraph 7 of the Sixth Amendment to the Lease is hereby deleted in its entirety and replaced
with the following:

Tenant shall have the right to extend the Term of the Lease for one (1) extension term of
one (1) year (the “Second Extended Term”) which shall commence on May 1, 2010 and end on
April 30, 2011 unless the Second Extended Term shall sooner terminate pursuant to any of the
terms of this Lease or otherwise. The Second Extended Term shall commence only if Tenant
shall have notified Landlord in writing of Tenant’s exercise of such extension right not
later than December 15, 2009, and at the time of the exercise of such right and immediately
prior to the then Expiration Date, this Lease is in full force and effect and no Default
shall have occurred and be continuing hereunder. Time is of the essence with respect to the
giving of the notice of Tenant’s exercise of the extension right. The Second Extended Term
shall be upon all of the agreements, terms, covenants and conditions hereof binding upon
Tenant, except that (a) Tenant shall pay Base Rent to Landlord in accordance with Section 1
of the Lease at the rate of $14,250.00 per month, (b) Landlord shall have no obligation to
perform any work or make any contribution to work performed to prepare the Premises for
Tenant’s use, and (c) Tenant shall have no further right to extend the Term. Upon the
exercise of the extension option by Tenant, (i) the Second Extended Term shall be added to
and become part of the Term (but shall not be considered part of the initial term or First
Extended Term), (ii) any reference to “this Lease”, to the “Term”, the “term of this Lease”
or any similar expression shall be deemed to include the Second Extended Term, and (iii) the
expiration date of the Second Extended Term shall become the Expiration Date. Tenant shall
have the right to exercise its option to extend for all of the Premises or for either (a)
the portion of the Premises containing approximately 5,199 rentable square feet and known as
Suite 220 and described herein as the Additional Premises or (b) the portion of the Premises
containing approximately 6,801 rentable square feet and known as Suite 280. If Tenant
elects to extend the Term of the Lease with respect to only a portion of the Premises, as
provided above, then Tenant shall vacate the portion of the Premises for which the Lease is
not being extended on or before the then current Expiration Date and Landlord and Tenant
shall promptly enter into an amendment to the Lease deleting the applicable Suite from the
Premises and making such further adjustments as may be appropriate, including, without
limitation, proportionate reductions in the Base Rent, the Tenant’s Proportionate Share and
the allocation of Parking Spaces.

5. Real Estate Brokers. Tenant represents that it has dealt with, and only with, Van
Vlissingen and Co., as broker in connection with this Amendment, and that, insofar as Tenant knows,
no other broker negotiated this Amendment or is entitled to any commission in connection therewith.
Tenant agrees to indemnify and hold Landlord harmless from all damages, liability and expense
(including reasonable attorneys’ fees) arising from any claims or demands of any other broker or
brokers or finders in connection with its participating with Tenant in the negotiating of this
Amendment.

 

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6. Lease in Full Force and Effect. Except for the provisions of this Amendment, all
the terms, covenants and conditions of the Lease and all the rights and obligations of Landlord and
Tenant thereunder, shall remain in full force and effect, and are not otherwise altered, amended,
revised or changed.

7. Estoppel. Tenant and Landlord hereby each acknowledge that as of the date hereof,
they have no claims arising under the Lease against the other party or its agents, or any one or
more of the foregoing, and that neither knows of any default or failure on the part of the other
party to keep or perform any covenant, condition or undertaking to be kept or performed by such
other party under the Lease.

8. Exculpatory Provisions. It is expressly understood and agreed by and between the
parties hereto, anything herein to the contrary notwithstanding, that each and all of the
representations, warranties, covenants, undertakings and agreements herein made on the part of any
Landlord while in form purporting to be the representations, warranties, covenants, undertakings,
and agreements of such Landlord are nevertheless each and every one of them made and intended, not
as personal representations, warranties, covenants, undertakings, and agreements by such Landlord
or for the purpose or with the intention of binding such Landlord personally, but are made and
intended for the purpose only of subjecting such Landlord’s interest in the Building, the Land and
the Premises to the terms of this Amendment and for no other purpose whatsoever, and in case of
default hereunder by any Landlord (or default through, under, or by any of its agents or
representatives), the Tenant shall look solely to the interests of such Landlord in the Building
and Land; that neither Landlord nor Chicago Title Land Trust Company, as Trustee of Trust No
113370-03 shall have any personal liability to pay any indebtedness accruing hereunder or to
perform any covenant, either express or implied, herein contained and no liability or duty shall
rest upon any Landlord which is a land trust to sequester the trust estate or the rents, issues and
profits arising therefrom, or the proceeds arising from any sale or other disposition thereof; that
no personal liability or personal responsibility of any sort is assumed by, nor shall at any time
be asserted or enforceable against, Chicago Title Land Trust Company, as Trustee under Trust No.
113370-03 or any beneficiaries under any land trust which may become the owner of the Building, on
account of this Amendment or on account of any representation, warranty, covenant, undertaking or
agreement of Landlord in this Amendment contained, either express or implied, all such personal
liability, if any, being expressly waived and released by Tenant and by all persons claiming by,
through, or under Tenant; and that this Amendment is executed and delivered by the undersigned
Landlord not in its own right, but solely in the exercise of the powers conferred upon it as such
Trustee.

 

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IN WITNESS WHEREOF, the parties have caused this Amendment to be executed on the date first
above written.

	 	 	 	 	 
	 	LANDLORD:

111 BARCLAY ASSOCIATES

 	 
	 	By:  	Van Vlissingen & Co., its authorized agent
 	 
	 	 	 
	 	By:  	/s/ Charles R. Lamphere
 	 
	 	 	Its: President 	 
	 	 	 	 
	 	TENANT:

BIOSANTE PHARMACEUTICALS, INC.

 	 
	 	By:  	/s/ Phillip B. Donenberg
 	 
	 	 	Its:  CFO 	 

 

4Exhibit 10.23

Exhibit 10.23

EIGHTH AMENDMENT TO LEASE

THIS EIGHTH AMENDMENT TO LEASE (“Amendment”) made as of the 8th day of September, 2009, by and
between 111 BARCLAY ASSOCIATES (“Landlord”), sole beneficiary under CHICAGO TITLE LAND TRUST
COMPANY, as successor trustee to LASALLE BANK NATIONAL ASSOCIATION, as successor trustee
(“Trustee”) to AMERICAN NATIONAL BANK AND TRUST COMPANY OF CHICAGO, as Trustee under Trust
Agreement (“Trust”) dated January 1, 1991 and known as Trust No. 113370-03 (“Landlord”) and
BIOSANTE PHARMACEUTICALS, INC. (“Tenant”).

RECITALS:

WHEREAS, Landlord and Tenant entered into that certain Lease dated December 19, 2003, as
amended by First Amendment to Lease dated February 26, 2004, as modified by Letter Amendment dated
March 19, 2004, as amended by Second Amendment to Lease dated January 4, 2005, as amended by Third
Amendment to Lease dated January 27, 2006, as amended by Fourth Amendment to Lease dated March 7,
2007, as amended by Fifth Amendment to Lease dated November 2, 2007, as amended by Sixth Amendment
to Lease dated April 18, 2008, and as amended by Seventh Amendment to Lease dated November 17, 2008
(the original lease, as amended, the “Existing Lease”, and the Existing Lease as amended by this
Amendment, the “Lease”) which Lease demised to Tenant a portion of the 2nd floor known
as Suite 280 and Suite 220 (“Premises”) of the building known as 111 Barclay Boulevard,
Lincolnshire, Illinois (“Building”); and

WHEREAS, Tenant desires to extend the Term of the Lease for the entire Premises and the
Landlord and Tenant desire to amend the Existing Lease to modify the Existing Lease in certain
other respects.

NOW, THEREFORE, in consideration of the mutual covenants and conditions contained herein, the
Lease is hereby further amended as follows:

1. Recitals. The Recitals are true and correct in all material respects and are
incorporated as if fully set forth herein.

2. Defined Terms. Capitalized terms used but not defined herein shall have the
meaning assigned to them in the Existing Lease.

3. Term. The Term of the Lease is hereby extended to April 30, 2012 on the same terms
and conditions as set forth in the Lease, except as modified herein and unless sooner terminated
pursuant to the terms of the Lease.

4. Rent. As of April 1, 2010 the Base Rent payable under the Lease shall be as
follows:

	 	 	 	 	 
	 	 	Annual	 	Monthly
	Period	 	Base Rent	 	Installment
	5/1/10-4/30/12
	 	$171,000.00
	 	$14,250.00

 

 

 

5. Work. Landlord shall, at Landlord’s expense, do the following work within the
Premises: (a) replace the carpeting in Suite 280 with Building Standard carpeting (color to be
selected by Tenant from Building Standard palette; (b) provide new vinyl base in Suite 280;
(c) paint suite 280 in it’s entirety (d) paint around existing furniture in Suite 220 (furniture is
not to be moved and existing carpeting is not to be removed). The work to be performed by Landlord
shall commence as soon as Tenant and Landlord coordinate their schedules.

6. No Extended Term. Tenant’s option to extend the term of the Lease as provided in
the Seventh Amendment to the Lease is hereby deleted in its entirety. The Tenant shall have no
option to extend the Term of this Lease.

7. Real Estate Brokers. Tenant represents that it has dealt with, and only with, Van
Vlissingen and Co., as broker in connection with this Amendment, and that, insofar as Tenant knows,
no other broker negotiated this Amendment or is entitled to any commission in connection therewith.
Tenant agrees to indemnify and hold Landlord harmless from all damages, liability and expense
(including reasonable attorneys’ fees) arising from any claims or demands of any other broker or
brokers or finders in connection with its participating with Tenant in the negotiating of this
Amendment.

8. Lease in Full Force and Effect. Except for the provisions of this Amendment, all
the terms, covenants and conditions of the Lease and all the rights and obligations of Landlord and
Tenant thereunder, shall remain in full force and effect, and are not otherwise altered, amended,
revised or changed.

9. Estoppel. Tenant and Landlord hereby each acknowledge that as of the date hereof,
they have no claims arising under the Lease against the other party or its agents, or any one or
more of the foregoing, and that neither knows of any default or failure on the part of the other
party to keep or perform any covenant, condition or undertaking to be kept or performed by such
other party under the Lease.

 

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10. Exculpatory Provisions. It is expressly understood and agreed by and between the
parties hereto, anything herein to the contrary notwithstanding, that each and all of the
representations, warranties, covenants, undertakings and agreements herein made on the part of any
Landlord while in form purporting to be the representations, warranties, covenants, undertakings,
and agreements of such Landlord are nevertheless each and every one of them made and intended, not
as personal representations, warranties, covenants, undertakings, and agreements by such Landlord
or for the purpose or with the intention of binding such Landlord personally, but are made and
intended for the purpose only of subjecting such Landlord’s interest in the Building, the Land and
the Premises to the terms of this Amendment and for no other purpose whatsoever, and in case of
default hereunder by any Landlord (or default through, under, or by any of its agents or
representatives), the Tenant shall look solely to the interests of such Landlord in the Building
and Land; that neither Landlord nor Chicago Title Land Trust Company, as Trustee of Trust No
113370-03 shall have any personal liability to pay any indebtedness accruing hereunder or to
perform any covenant, either express or implied, herein contained and no liability or duty shall
rest upon any Landlord which is a land trust to sequester the trust estate or the rents, issues and
profits arising therefrom, or the proceeds arising from any sale or other disposition thereof; that
no personal liability or personal responsibility of any sort is assumed by, nor shall at any time
be asserted or enforceable against, Chicago Title Land Trust Company, as Trustee under Trust No.
113370-03 or any beneficiaries under any land trust which may become the owner of the Building, on
account of this Amendment or on account of any representation, warranty, covenant, undertaking or
agreement of Landlord in this Amendment
contained, either express or implied, all such personal liability, if any, being expressly
waived and released by Tenant and by all persons claiming by, through, or under Tenant; and that
this Amendment is executed and delivered by the undersigned Landlord not in its own right, but
solely in the exercise of the powers conferred upon it as such Trustee.

SIGNATURES APPEAR ON NEXT PAGE

 

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IN WITNESS WHEREOF, the parties have caused this Amendment to be executed on the date first
above written.

	 	 	 	 	 
	 	LANDLORD:

111 BARCLAY ASSOCIATES

 	 
	 	By:  	Van Vlissingen & Co., its authorized agent
 	 
	 	 	 
	 	By:  	/s/ Charles R. Lamphere
 	 
	 	 	Its: President 	 

	 
	 	TENANT:

BIOSANTE PHARMACEUTICALS, INC.

 	 
	 	By:  	/s/ Phillip B. Donenberg
 	 
	 	 	Its:  CFO, 9/8/09 	 

 

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