Document:

Form of Subordinated Indenture

 EXHIBIT 4.15 
  
 FORM OF INDENTURE TO BE ENTERED INTO 
  
 NUVELO, INC. 
  
 INDENTURE 
  
 Dated as of             , 2005 
  
 U.S. BANK NATIONAL ASSOCIATION 
  
 Trustee 
  
 Subordinated Debt Securities 
  

 TABLE OF CONTENTS 
  

					
	 	  	 	  	PAGE

	ARTICLE 1     DEFINITIONS AND INCORPORATION BY REFERENCE	  	1
			
	 Section 1.1
	  	Definitions	  	1
			
	 Section 1.2
	  	Other Definitions	  	6
			
	 Section 1.3
	  	Incorporation by Reference of Trust Indenture Act	  	7
			
	 Section 1.4
	  	Rules of Construction	  	7
		
	ARTICLE 2     THE SECURITIES	  	8
			
	 Section 2.1
	  	Issuable in Series	  	8
			
	 Section 2.2
	  	Establishment of Terms of Series of Securities	  	8
			
	 Section 2.3
	  	Execution and Authentication	  	10
			
	 Section 2.4
	  	Registrar and Paying Agent	  	11
			
	 Section 2.5
	  	Paying Agent to Hold Money in Trust	  	12
			
	 Section 2.6
	  	Securityholder Lists	  	12
			
	 Section 2.7
	  	Transfer and Exchange	  	12
			
	 Section 2.8
	  	Mutilated, Destroyed, Lost and Stolen Securities	  	13
			
	 Section 2.9
	  	Outstanding Securities	  	13
			
	 Section 2.10
	  	Treasury Securities	  	14
			
	 Section 2.11
	  	Temporary Securities	  	14
			
	 Section 2.12
	  	Cancellation	  	14
			
	 Section 2.13
	  	Defaulted Interest	  	15
			
	 Section 2.14
	  	Global Securities	  	15
			
	 Section 2.15
	  	CUSIP Numbers	  	16
		
	ARTICLE 3     REDEMPTION	  	16
			
	 Section 3.1
	  	Notice to Trustee	  	16
			
	 Section 3.2
	  	Selection of Securities to be Redeemed	  	17
			
	 Section 3.3
	  	Notice of Redemption	  	17
			
	 Section 3.4
	  	Effect of Notice of Redemption	  	17
			
	 Section 3.5
	  	Deposit of Redemption Price	  	18
			
	 Section 3.6
	  	Securities Redeemed in Part	  	18
		
	ARTICLE 4     COVENANTS	  	18
			
	 Section 4.1
	  	Payment of Principal and Interest	  	18
			
	 Section 4.2
	  	SEC Reports	  	18
			
	 Section 4.3
	  	Compliance Certificate	  	18

  

 i. 

 TABLE OF CONTENTS 
 (CONTINUED) 
  

					
	 	  	 	  	PAGE

			
	 Section 4.4
	  	Corporate Existence	  	19
			
	 Section 4.5
	  	Taxes	  	19
		
	ARTICLE 5     SUCCESSORS	  	19
			
	 Section 5.1
	  	When Company May Merge, Etc.	  	19
			
	 Section 5.2
	  	Successor Corporation Substituted	  	19
		
	ARTICLE 6     DEFAULTS AND REMEDIES	  	20
			
	 Section 6.1
	  	Events of Default	  	20
			
	 Section 6.2
	  	Acceleration of Maturity; Rescission and Annulment	  	21
			
	 Section 6.3
	  	Collection of Indebtedness and Suits for Enforcement by Trustee	  	22
			
	 Section 6.4
	  	Trustee May File Proofs of Claim	  	23
			
	 Section 6.5
	  	Trustee May Enforce Claims Without Possession of Securities	  	23
			
	 Section 6.6
	  	Application of Money Collected	  	24
			
	 Section 6.7
	  	Limitation on Suits	  	24
			
	 Section 6.8
	  	Unconditional Right of Holders to Receive Principal and Interest	  	25
			
	 Section 6.9
	  	Restoration of Rights and Remedies	  	25
			
	 Section 6.10
	  	Rights and Remedies Cumulative	  	25
			
	 Section 6.11
	  	Delay or Omission Not Waiver	  	25
			
	 Section 6.12
	  	Control by Holders	  	25
			
	 Section 6.13
	  	Waiver of Past Defaults	  	26
			
	 Section 6.14
	  	Undertaking for Costs	  	26
		
	ARTICLE 7     TRUSTEE	  	26
			
	 Section 7.1
	  	Duties of Trustee	  	26
			
	 Section 7.2
	  	Rights of Trustee	  	28
			
	 Section 7.3
	  	Individual Rights of Trustee	  	28
			
	 Section 7.4
	  	Trustee’s Disclaimer	  	29
			
	 Section 7.5
	  	Notice of Defaults	  	29
			
	 Section 7.6
	  	Reports by Trustee to Holders	  	29
			
	 Section 7.7
	  	Compensation and Indemnity	  	29
			
	 Section 7.8
	  	Replacement of Trustee	  	30

  

 ii. 

 TABLE OF CONTENTS 
 (CONTINUED) 
  

					
	 	  	 	  	PAGE

			
	 Section 7.9
	  	Successor Trustee by Merger, etc.	  	31
			
	 Section 7.10
	  	Eligibility; Disqualification	  	31
			
	 Section 7.11
	  	Preferential Collection of Claims Against Company	  	31
		
	ARTICLE 8     SATISFACTION AND DISCHARGE; DEFEASANCE	  	31
			
	 Section 8.1
	  	Satisfaction and Discharge of Indenture	  	31
			
	 Section 8.2
	  	Application of Trust Funds; Indemnification	  	32
			
	 Section 8.3
	  	Legal Defeasance of Securities of any Series	  	33
			
	 Section 8.4
	  	Covenant Defeasance	  	34
			
	 Section 8.5
	  	Repayment to Company	  	36
			
	 Section 8.6
	  	Reinstatement	  	36
		
	ARTICLE 9     AMENDMENTS AND WAIVERS	  	36
			
	 Section 9.1
	  	Without Consent of Holders	  	36
			
	 Section 9.2
	  	With Consent of Holders	  	37
			
	 Section 9.3
	  	Limitations	  	37
			
	 Section 9.4
	  	Compliance with Trust Indenture Act	  	38
			
	 Section 9.5
	  	Revocation and Effect of Consents	  	38
			
	 Section 9.6
	  	Notation on or Exchange of Securities	  	38
			
	 Section 9.7
	  	Trustee Protected	  	38
		
	ARTICLE 10     MISCELLANEOUS	  	39
			
	 Section 10.1
	  	Trust Indenture Act Controls	  	39
			
	 Section 10.2
	  	Notices	  	39
			
	 Section 10.3
	  	Communication by Holders with Other Holders	  	40
			
	 Section 10.4
	  	Certificate and Opinion as to Conditions Precedent	  	40
			
	 Section 10.5
	  	Statements Required in Certificate or Opinion	  	40
			
	 Section 10.6
	  	Rules by Trustee and Agents	  	40
			
	 Section 10.7
	  	Legal Holidays	  	41
			
	 Section 10.8
	  	No Recourse Against Others	  	41
			
	 Section 10.9
	  	Counterparts	  	41
			
	 Section 10.10
	  	Governing Laws	  	41
			
	 Section 10.11
	  	No Adverse Interpretation of Other Agreements	  	41

  

 iii. 

 TABLE OF CONTENTS 
 (CONTINUED) 
  

					
	 	  	 	  	PAGE

			
	 Section 10.12
	  	Successors	  	41
			
	 Section 10.13
	  	Severability	  	41
			
	 Section 10.14
	  	Table of Contents, Headings, Etc.	  	42
			
	 Section 10.15
	  	Securities in a Foreign Currency or in ECU	  	42
			
	 Section 10.16
	  	Judgment Currency	  	42
		
	ARTICLE 11     SINKING FUNDS	  	43
			
	 Section 11.1
	  	Applicability of Article	  	43
			
	 Section 11.2
	  	Satisfaction of Sinking Fund Payments with Securities	  	43
			
	 Section 11.3
	  	Redemption of Securities for Sinking Fund	  	44
		
	ARTICLE 12     SUBORDINATION OF SECURITIES	  	44
			
	 Section 12.1
	  	Agreement of Subordination	  	44
			
	 Section 12.2
	  	Payments to Holders	  	45
			
	 Section 12.3
	  	Subrogation of Securities	  	47
			
	 Section 12.4
	  	Authorization to Effect Subordination	  	48
			
	 Section 12.5
	  	Notice to Trustee	  	48
			
	 Section 12.6
	  	Trustee’s Relation to Senior Indebtedness	  	49
			
	 Section 12.7
	  	No Impairment of Subordination	  	50
			
	 Section 12.8
	  	Article Applicable to Paying Agents	  	50
			
	 Section 12.9
	  	Senior Indebtedness Entitled to Rely	  	50

  

 iv. 

 NUVELO, INC. 
  
 Reconciliation and tie between Trust Indenture Act of 1939 and 
 Indenture, dated as of             , 2005 
  

			
	 Section 310(a) (1)
	  	7.10
	 (a) (2)
	  	7.10
	 (a) (3)
	  	Not Applicable
	 (a) (4)
	  	Not Applicable
	 (a) (5)
	  	7.10
	 (b)
	  	7.10
	 Section 311(a)
	  	7.11
	 (b)
	  	7.11
	 (c)
	  	Not Applicable
	 Section 312(a)
	  	2.6
	 (b)
	  	10.3
	 (c)
	  	10.3
	 Section 313(a)
	  	7.6
	 (b) (1)
	  	7.6
	 (b) (2)
	  	7.6
	 (c) (1)
	  	7.6
	 (d)
	  	7.6
	 Section 314(a)
	  	4.2, 10.5
	 (b)
	  	Not Applicable
	 (c) (1)
	  	10.4
	 (c) (2)
	  	10.4
	 (c) (3)
	  	Not Applicable
	 (d)
	  	Not Applicable
	 (e)
	  	10.5
	 (f)
	  	Not Applicable
	 Section 315(a)
	  	7.1
	 (b)
	  	7.5
	 (c)
	  	7.1
	 (d)
	  	7.1
	 (e)
	  	6.14
	 Section 316(a)
	  	2.10
	 (a) (1)(a)
	  	6.12
	 (a) (1)(b)
	  	6.13
	 (b)
	  	6.8
	 Section 317(a)(1)
	  	6.3
	 (a)(2)
	  	6.4
	 (b)
	  	2.5
	 Section 318(a)
	  	10.1

  
 Note: This reconciliation and tie
shall not, for any purpose, be deemed to be part of the Indenture. 
  

 v. 

 Indenture dated as of
                    , 2005 between Nuvelo, Inc., a Delaware corporation (“Company”), and U.S. Bank National Association, a national
banking association (“Trustee”). 
  
 Each party agrees
as follows for the benefit of the other party and for the equal and ratable benefit of the Holders of the Securities issued under this Indenture. 
  
 ARTICLE 1 
  
 DEFINITIONS AND INCORPORATION BY REFERENCE 
  
 Section 1.1 Definitions. 
  
 “Additional Amounts” means any additional amounts which are required hereby or by any Security, under circumstances specified herein or therein,
to be paid by the Company in respect of certain taxes imposed on Holders specified therein and which are owing to such Holders. 
  
 “Affiliate” of any specified person means any other person directly or indirectly controlling or controlled by or under direct or indirect
common control with such specified person. For the purposes of this definition, “control” (including, with correlative meanings, the terms “controlled by” and “under common control with”), as used with respect to any
person, shall mean the possession, directly or indirectly, of the power to direct or cause the direction of the management or policies of such person, whether through the ownership of voting securities or by agreement or otherwise. 
  
 “Agent” means any Registrar, Paying Agent, Service Agent or
authenticating agent. 
  
 “Authorized Newspaper” means a
newspaper in an official language of the country of publication customarily published at least once a day for at least five days in each calendar week and of general circulation in the place in connection with which the term is used. If it shall be
impractical to make any publication of any notice required hereby in an Authorized Newspaper, any publication or other notice in lieu thereof that is made or given by the Trustee shall constitute a sufficient publication of such notice. 

 
 “Bearer” means anyone in possession from time to time of a
Bearer Security. 
  
 “Bearer Security” means any
Security, including any interest coupon appertaining thereto, that does not provide for the identification of the Holder thereof. 
  
 “Board of Directors” means the Board of Directors of the Company or any duly authorized committee thereof. 
  
 “Board Resolution” means a copy of a resolution certified by the
Secretary or an Assistant Secretary of the Company to have been adopted by the Board of Directors or pursuant to authorization by the Board of Directors and to be in full force and effect on the date of the certificate, and delivered to the Trustee.

  

 1. 

 “Business Day” means, unless otherwise provided by Board Resolution, Officers’ Certificate
or supplemental indenture hereto for a particular Series, any day except a Saturday, Sunday or a legal holiday in The City of New York or the City of San Francisco on which banking institutions are authorized or required by law, regulation or
executive order to close. 
  
 “Company” means the party
named as such above until a successor replaces it and thereafter means the successor. 
  
 “Company Order” means a written order signed in the name of the Company by two Officers, one of whom must be the Company’s chief executive officer, chief financial officer or principal accounting
officer. 
  
 “Company Request” means a written request
signed in the name of the Company by its Chairman of the Board, a President or a Vice President, and by its Treasurer, an Assistant Treasurer, its Secretary or an Assistant Secretary, and delivered to the Trustee. 
  
 “Corporate Trust Office” means the office of the Trustee at which
at any particular time its corporate trust business shall be principally administered. 
  
 “Default” means any event which is, or after notice or passage of time would be, an Event of Default. 
  
 “Depository” means, with respect to the Securities of any Series issuable or issued in whole or in part in the form of one or more Global
Securities, the person designated as Depository for such Series by the Company, which Depository shall be a clearing agency registered under the Exchange Act; and if at any time there is more than one such person, “Depository” as used with
respect to the Securities of any Series shall mean the Depository with respect to the Securities of such Series. 
  
 “Designated Senior Indebtedness” means any of our senior indebtedness that expressly provides that it is “designated senior
indebtedness” for purposes of this Indenture (provided that the instrument, agreement or other document creating or evidencing such Senior Indebtedness may place limitations and conditions on the right of such Senior Indebtedness to exercise
the rights of Designated Senior Indebtedness). 
  
 “Discount
Security” means any Security that provides for an amount less than the stated principal amount thereof to be due and payable upon declaration of acceleration of the maturity thereof pursuant to Section 6.2. 
  
 “Dollars” means the currency of The United States of America.

  
 “ECU” means the European Currency Unit as determined
by the Commission of the European Union. 
  

 2. 

 “Exchange Act” means the Securities Exchange Act of 1934, as amended. 
  
 “Foreign Currency” means any currency or currency unit issued by a
government other than the government of The United States of America. 
  
 “Foreign Government Obligations” means with respect to Securities of any Series that are denominated in a Foreign Currency, (i) direct obligations of the government that issued or caused to be issued such currency for the payment
of which obligations its full faith and credit is pledged or (ii) obligations of a person controlled or supervised by or acting as an agency or instrumentality of such government the timely payment of which is unconditionally guaranteed as a full
faith and credit obligation by such government, which, in either case under clauses (i) or (ii), are not callable or redeemable at the option of the issuer thereof. 
  
 “Global Security” or “Global Securities” means a Security or Securities, as the case may be, in the form
established pursuant to Section 2.2 evidencing all or part of a Series of Securities, issued to the Depository for such Series or its nominee, and registered in the name of such Depository or nominee. 
  
 “Holder” or “Securityholder” means a person in whose name
a Security is registered or the holder of a Bearer Security. 
  
 “indebtedness” means, with respect to any person, and without duplication, (a) all indebtedness, obligations and other liabilities (contingent or otherwise) of such person for borrowed money (including obligations of the Company
in respect of overdrafts, foreign exchange contracts, currency exchange agreements, interest rate protection agreements, and any loans or advances from banks, whether or not evidenced by notes or similar instruments) or evidenced by bonds,
debentures, notes or similar instruments (whether or not the recourse of the lender is to the whole of the assets of such person or to only a portion thereof) (other than any account payable or other accrued current liability or obligation incurred
in the ordinary course of business in connection with the obtaining of materials or services), (b) all reimbursement obligations and other liabilities (contingent or otherwise) of such person with respect to letters of credit, bank guarantees or
bankers’ acceptances, (c) all obligations and liabilities (contingent or otherwise) in respect of leases of such person required, in conformity with generally accepted accounting principles, to be accounted for as capitalized lease obligations
on the balance sheet of such person and all obligations and all other obligations and liabilities, contingent or otherwise, as lessee under leases for facility equipment (and related assets leased together with such equipment) and under any lease or
related document (including a purchase agreement, conditional sale or other title retention or synthetic lease agreement) in connection with the lease of real property or improvement thereon (or any personal property included as part of any such
lease) which provides that such Person is contractually obligated to purchase or cause a third party to purchase the leased property or pay an agreed upon residual value of the leased property, including the obligations under such lease or related
document to purchase or cause a third party to purchase such leased property (whether or not such lease transaction is characterized as an operating lease or a capitalized lease in accordance with GAAP) or pay an agreed upon residual value of the
leased property to the lessor; (d) all obligations of such person (contingent or otherwise) with respect to an interest rate or other swap, cap or collar agreement or other similar instrument or agreement or foreign currency hedge, exchange,
purchase or similar instrument or 

  

 3. 

 
agreement, (e) all direct or indirect guaranties or similar agreements by such person in respect of, and obligations or liabilities (contingent or otherwise)
of such person to purchase or otherwise acquire or otherwise assure a creditor against loss in respect of indebtedness, obligations or liabilities of another person of the kind described in clauses (a) through (d), (f) any indebtedness or other
obligations described in clauses (a) through (e) secured by any mortgage, pledge, lien or other encumbrance existing on property which is owned or held by such person, regardless of whether the indebtedness or other obligation secured thereby shall
have been assumed by such person and (g) any and all refinancings, replacements, deferrals, renewals, extensions and refundings of, or amendments, modifications or supplements to, any indebtedness, obligation or liability of the kind described in
clauses (a) through (f). 
  
 “Indenture” means this
Indenture as amended from time to time and shall include the form and terms of particular Series of Securities established as contemplated hereunder. 
  
 “interest” with respect to any Discount Security which by its terms bears interest only after Maturity, means interest payable after Maturity.

  
 “Maturity,” when used with respect to any Security
or installment of principal thereof, means the date on which the principal of such Security or such installment of principal becomes due and payable as therein or herein provided, whether at the Stated Maturity or by declaration of acceleration,
call for redemption, notice of option to elect repayment or otherwise. 
  
 “Officer” means the Chairman of the Board, any President, any Vice-President, the Treasurer, the Secretary, any Assistant Treasurer or any Assistant Secretary of the Company. 
  
 “Officers’ Certificate” means a certificate signed by two
Officers, one of whom must be the Company’s principal executive officer, principal financial officer or principal accounting officer. 
  
 “Opinion of Counsel” means a written opinion of legal counsel who is acceptable to the Trustee. The counsel may be an employee of or counsel to
the Company. 
  
 “person” means any individual,
corporation, partnership, joint venture, association, limited liability company, joint-stock company, trust, unincorporated organization or government or any agency or political subdivision thereof. 
  
 “principal” of a Security means the principal of the Security plus,
when appropriate, the premium, if any, on, and any Additional Amounts in respect of, the Security. 
  
 “Representative” means the (a) indenture trustee or other trustee, agent or representative for any Senior Indebtedness or (b) with respect to
any Senior Indebtedness that does not have any such trustee, agent or other representative, (i) in the case of such Senior Indebtedness issued pursuant to an agreement providing for voting arrangements as among the holders or owners of such Senior
Indebtedness, any holder or owner of such Senior Indebtedness acting with the consent of the required persons necessary to bind such holders or owners of such Senior Indebtedness and (ii) in the case of all other such Senior Indebtedness, the holder
or owner of such Senior Indebtedness. 
  

 4. 

 “Responsible Officer” means any officer of the Trustee in its Corporate Trust Office and also
means, with respect to a particular corporate trust matter, any other officer to whom any corporate trust matter is referred because of his or her knowledge of and familiarity with a particular subject. 
  
 “SEC” means the Securities and Exchange Commission. 
  
 “Securities” means the debentures, notes or other debt instruments
of the Company of any Series authenticated and delivered under this Indenture. 
  
 “Senior Indebtedness” means the principal, premium, if any, interest, including any interest accruing after bankruptcy, and rent or termination payment on or other amounts due on our current or future
Indebtedness, whether created, incurred, assumed, guaranteed or in effect guaranteed by us, including any deferrals, renewals, extensions, refundings, amendments, modifications or supplements to the above. However, Senior Indebtedness does not
include: (i) Indebtedness that expressly provides that it shall not be senior in right of payment to the Securities or expressly provides that it is on the same basis or junior to the Securities; (ii) our indebtedness to any of our majority-owned
subsidiaries; and (iii) the Securities. 
  
 “Series” or
“Series of Securities” means each series of debentures, notes or other debt instruments of the Company created pursuant to Sections 2.1 and 2.2 hereof. 
  
 “Stated Maturity” when used with respect to any Security or any installment of principal thereof or interest
thereon, means the date specified in such Security as the fixed date on which the principal of such Security or such installment of principal or interest is due and payable. 
  
 “Subsidiary” of any specified person means any corporation of which at least a majority of the outstanding stock
having by the terms thereof ordinary voting power for the election of directors of such corporation (irrespective of whether or not at the time stock of any other class or classes of such corporation shall have or might have voting power by reason
of the happening of any contingency) is at the time directly or indirectly owned by such person, or by one or more other Subsidiaries, or by such person and one or more other Subsidiaries. 
  
 “TIA” means the Trust Indenture Act of 1939 (15 U.S. Code Sections
77aaa-77bbbb) as in effect on the date of this Indenture; provided, however, that in the event the Trust Indenture Act of 1939 is amended after such date, “TIA” means, to the extent required by any such amendment, the Trust Indenture Act
as so amended. 
  
 “Trustee” means the person named as
the “Trustee” in the first paragraph of this instrument until a successor Trustee shall have become such pursuant to the applicable provisions of this Indenture, and thereafter “Trustee” shall mean or include each person who is
then a Trustee hereunder, and if at any time there is more than one such person, “Trustee” as used with respect to the Securities of any Series shall mean the Trustee with respect to Securities of that Series. 
  
 “U.S. Government Obligations” means securities which are (i) direct
obligations of The United States of America for the payment of which its full faith and credit is pledged or (ii) obligations of a person controlled or supervised by and acting as an agency or instrumentality of 

  

 5. 

 
The United States of America the payment of which is unconditionally guaranteed as a full faith and credit obligation by The United States of America, and
which in the case of (i) and (ii) are not callable or redeemable at the option of the issuer thereof, and shall also include a depository receipt issued by a bank or trust company as custodian with respect to any such U.S. Government Obligation or a
specific payment of interest on or principal of any such U.S. Government Obligation held by such custodian for the account of the holder of a depository receipt, provided that (except as required by law) such custodian is not authorized to make any
deduction from the amount payable to the holder of such depository receipt from any amount received by the custodian in respect of the U.S. Government Obligation evidenced by such depository receipt. 
  
 Section 1.2 Other Definitions. 
  

			
	 TERM

	  	DEFINED IN
SECTION

	 “Bankruptcy Law”
	  	6.1
	 “Custodian”
	  	6.1
	 “Event of Default”
	  	6.1
	 “Journal”
	  	10.15
	 “Judgment Currency”
	  	10.16
	 “Legal Holiday”
	  	10.7
	 “mandatory sinking fund payment”
	  	11.1
	 “Market Exchange Rate”
	  	10.15
	 “New York Banking Day”
	  	10.16
	 “optional sinking fund payment”
	  	11.1
	 “Paying Agent”
	  	2.4
	 “Payment Blockage Notice”
	  	12.2
	 “Registrar”
	  	2.4
	 “Required Currency”
	  	10.16
	 “Service Agent”
	  	2.4
	 “successor person”
	  	5.1

  

 6. 

 Section 1.3 Incorporation by Reference of Trust Indenture Act. 
  
 Whenever this Indenture refers to a provision of the TIA, the provision is
incorporated by reference in and made a part of this Indenture. The following TIA terms used in this Indenture have the following meanings: 
  
 “Commission” means the SEC. 
  
 “indenture securities” means the Securities. “indenture security holder” means a Securityholder. 
  
 “indenture to be qualified” means this Indenture. 
  
 “indenture trustee” or “institutional trustee” means the
Trustee. 
  
 “obligor” on the indenture securities means
the Company and any successor obligor upon the Securities. 
  
 All
other terms used in this Indenture that are defined by the TIA, defined by TIA reference to another statute or defined by SEC rule under the TIA and not otherwise defined herein are used herein as so defined. 
  
 Section 1.4 Rules of Construction. 
  
 Unless the context otherwise requires: 
  
 (a) a term has the meaning assigned to it;

  
 (b) an accounting term not otherwise
defined has the meaning assigned to it in accordance with generally accepted accounting principles; 
  
 (c) references to “generally accepted accounting principles” shall mean generally accepted accounting principles in
effect as of the time when and for the period as to which such accounting principles are to be applied; 
  
 (d) “or” is not exclusive; 
  
 (e) words in the singular include the plural, and in the plural include the singular; and 
  
 (f) provisions apply to successive events and
transactions. 
  

 7. 

 ARTICLE 2 
  

THE SECURITIES 
  
 Section 2.1 Issuable in Series. 
  
 The aggregate principal amount of Securities that may be authenticated and delivered under this Indenture is unlimited. The Securities may be issued in
one or more Series. All Securities of a Series shall be identical except as may be set forth in a Board Resolution, a supplemental indenture or an Officers’ Certificate detailing the adoption of the terms thereof pursuant to the authority
granted under a Board Resolution. In the case of Securities of a Series to be issued from time to time, the Board Resolution, Officers’ Certificate or supplemental indenture may provide for the method by which specified terms (such as interest
rate, maturity date, record date or date from which interest shall accrue) are to be determined. Securities may differ between Series in respect of any matters, provided that all Series of Securities shall be equally and ratably entitled to the
benefits of the Indenture but all Securities issued hereunder shall be subordinate and junior in right of payment, to the extent and in the manner set forth in Article XII, to all Senior Indebtedness of the Company. 
  
 Section 2.2 Establishment of Terms of Series of Securities.

  
 At or prior to the issuance of any Securities within a
Series, the following shall be established (as to the Series generally, in the case of Subsection 2.2.1 and either as to such Securities within the Series or as to the Series generally in the case of Subsections 2.2.2 through 2.2.22) by a Board
Resolution, a supplemental indenture or an Officers’ Certificate pursuant to authority granted under a Board Resolution: 
  
 2.2.1 the title of the Series (which shall distinguish the Securities of that particular Series from the Securities of any other
Series); 
  
 2.2.2 the price or prices
(expressed as a percentage of the principal amount thereof) at which the Securities of the Series will be issued; 
  
 2.2.3 any limit upon the aggregate principal amount of the Securities of the Series which may be authenticated and delivered under
this Indenture (except for Securities authenticated and delivered upon registration of transfer of, or in exchange for, or in lieu of, other Securities of the Series pursuant to Section 2.7, 2.8, 2.11, 3.6 or 9.6); 
  
 2.2.4 the date or dates on which the principal of the
Securities of the Series is payable; 
  
 2.2.5
the rate or rates (which may be fixed or variable) per annum or, if applicable, the method used to determine such rate or rates (including, but not limited to, any commodity, commodity index, stock exchange index or financial index) at which the
Securities of the Series shall bear interest, if any, the date or dates from which such interest, if any, shall accrue, the date or dates on which such interest, if any, shall commence and be payable and any regular record date for the interest
payable on any interest payment date; 
  

 8. 

 2.2.6 the place or places where the principal of and interest, if any, on the
Securities of the Series shall be payable, or the method of such payment, if by wire transfer, mail or other means; 
  
 2.2.7 if applicable, the period or periods within which, the price or prices at which and the terms and conditions upon which the
Securities of the Series may be redeemed, in whole or in part, at the option of the Company; 
  
 2.2.8 the obligation, if any, of the Company to redeem or purchase the Securities of the Series pursuant to any sinking fund or
analogous provisions or at the option of a Holder thereof and the period or periods within which, the price or prices at which and the terms and conditions upon which Securities of the Series shall be redeemed or purchased, in whole or in part,
pursuant to such obligation; 
  
 2.2.9 the
dates, if any, on which and the price or prices at which the Securities of the Series will be repurchased by the Company at the option of the Holders thereof and other detailed terms and provisions of such repurchase obligations; 
  
 2.2.10 if other than denominations of $1,000 and any
integral multiple thereof, the denominations in which the Securities of the Series shall be issuable; 
  
 2.2.11 the forms of the Securities of the Series in bearer or fully registered form (and, if in fully registered form, whether the
Securities will be issuable as Global Securities); 
  
 2.2.12 if other than the principal amount thereof, the portion of the principal amount of the Securities of the Series that shall be payable upon declaration of acceleration of the maturity thereof pursuant to Section 6.2;

  
 2.2.13 the currency of denomination of
the Securities of the Series, which may be Dollars or any Foreign Currency, including, but not limited to, the ECU, and if such currency of denomination is a composite currency other than the ECU, the agency or organization, if any, responsible for
overseeing such composite currency; 
  
 2.2.14
the designation of the currency, currencies or currency units in which payment of the principal of and interest, if any, on the Securities of the Series will be made; 
  
 2.2.15 if payments of principal of or interest, if any, on the Securities of the Series are to be
made in one or more currencies or currency units other than that or those in which such Securities are denominated, the manner in which the exchange rate with respect to such payments will be determined; 
  
 2.2.16 the manner in which the amounts of payment of
principal of or interest, if any, on the Securities of the Series will be determined, if such amounts may be determined by reference to an index based on a currency or currencies or by reference to a commodity, commodity index, stock exchange index
or financial index; 
  
 2.2.17 the
provisions, if any, relating to any security provided for the Securities of the Series; 
  

 9. 

 2.2.18 if the holders of Securities of the Series may convert or exchange the
Securities into or for securities of the Issuer or of other entities or other property, the period or periods within which, the rate or rates at which and the terms and conditions upon which Securities of the Series may be converted or exchanged, in
whole or in part; 
  
 2.2.19 any addition
to or change in the Events of Default which applies to any Securities of the Series and any change in the right of the Trustee or the requisite Holders of such Securities to declare the principal amount thereof due and payable pursuant to Section
6.2; 
  
 2.2.20 any addition to or change
in the covenants set forth in Articles IV or V which applies to Securities of the Series; 
  
 2.2.21 any other terms of the Securities of the Series (which terms shall not be inconsistent with the provisions of this
Indenture, except as permitted by Section 9.1, but which may modify or delete any provision of this Indenture insofar as it applies to such Series); and 
  
 2.2.22 any depositories, interest rate calculation agents, exchange rate calculation agents or other agents with respect to
Securities of such Series if other than those appointed herein. 
  
 All Securities of any one Series need not be issued at the same time and may be issued from time to time, consistent with the terms of this Indenture, if so provided by or pursuant to the Board Resolution, supplemental indenture or
Officers’ Certificate referred to above, and the authorized principal amount of any Series may not be increased to provide for issuances of additional Securities of such Series, unless otherwise provided in such Board Resolution, supplemental
indenture or Officers’ Certificate. 
  
 Section 2.3
Execution and Authentication. 
  
 Two Officers shall sign the
Securities for the Company by manual or facsimile signature. 
  
 If an Officer whose signature is on a Security no longer holds that office at the time the Security is authenticated, the Security shall nevertheless be valid. 
  
 A Security shall not be valid until authenticated by the manual signature of the Trustee or an authenticating agent. The
signature shall be conclusive evidence that the Security has been authenticated under this Indenture. 
  
 The Trustee shall at any time, and from time to time, authenticate Securities for original issue in the principal amount provided in the Board Resolution,
supplemental indenture hereto or Officers’ Certificate, upon receipt by the Trustee of a Company Order. Such Company Order may authorize authentication and delivery pursuant to oral or electronic instructions from the Company or its duly
authorized agent or agents, which oral instructions shall be promptly confirmed in writing. Each Security shall be dated the date of its authentication unless otherwise provided by a Board Resolution, a supplemental indenture hereto or an
Officers’ Certificate. 
  
 The aggregate principal amount of
Securities of any Series outstanding at any time may not exceed any limit upon the maximum principal amount for such Series set forth in the Board 

  

 10. 

 
Resolution, supplemental indenture hereto or Officers’ Certificate delivered pursuant to Section 2.2, except as provided in Section 2.8. 
  
 Prior to the issuance of Securities of any Series, the Trustee shall have
received and (subject to Section 7.2) shall be fully protected in relying on: (a) the Board Resolution, supplemental indenture hereto or Officers’ Certificate establishing the form of the Securities of that Series or of Securities within that
Series and the terms of the Securities of that Series or of Securities within that Series, (b) an Officers’ Certificate complying with Section 10.4, and (c) an Opinion of Counsel complying with Section 10.4. 
  
 The Trustee shall have the right to decline to authenticate and deliver any
Securities of such Series: (a) if the Trustee, being advised by counsel, determines that such action may not lawfully be taken; or (b) if the Trustee in good faith by its board of directors or trustees, executive committee or a trust committee of
directors and/or vice-presidents shall determine that such action would expose the Trustee to personal liability to Holders of any then outstanding Series of Securities. 
  
 The Trustee may appoint an authenticating agent acceptable to the Company to authenticate Securities. An authenticating
agent may authenticate Securities whenever the Trustee may do so. Each reference in this Indenture to authentication by the Trustee includes authentication by such agent. An authenticating agent has the same rights as an Agent to deal with the
Company or an Affiliate. 
  
 Section 2.4 Registrar and Paying
Agent. 
  
 The Company shall maintain, with respect to each
Series of Securities, at the place or places specified with respect to such Series pursuant to Section 2.2, an office or agency where Securities of such Series may be presented or surrendered for payment (“Paying Agent”), where Securities
of such Series may be surrendered for registration of transfer or exchange (“Registrar”) and where notices and demands to or upon the Company in respect of the Securities of such Series and this Indenture may be served (“Service
Agent”). The Registrar shall keep a register with respect to each Series of Securities and to their transfer and exchange. The Company will give prompt written notice to the Trustee of the name and address, and any change in the name or
address, of each Registrar, Paying Agent or Service Agent. If at any time the Company shall fail to maintain any such required Registrar, Paying Agent or Service Agent or shall fail to furnish the Trustee with the name and address thereof, such
presentations, surrenders, notices and demands may be made or served at the Corporate Trust Office of the Trustee, and the Company hereby appoints the Trustee as its agent to receive all such presentations, surrenders, notices and demands.

  
 The Company may also from time to time designate one or more
co-registrars, additional paying agents or additional service agents and may from time to time rescind such designations; provided, however, that no such designation or rescission shall in any manner relieve the Company of its obligations to
maintain a Registrar, Paying Agent and Service Agent in each place so specified pursuant to Section 2.2 for Securities of any Series for such purposes. The Company will give prompt written notice to the Trustee of any such designation or rescission
and of any change in the name or address of any such co-registrar, additional paying agent or 

  

 11. 

 
additional service agent. The term “Registrar” includes any co-registrar; the term “Paying Agent” includes any additional paying agent;
and the term “Service Agent” includes any additional service agent. 
  
 The Company hereby appoints the Trustee the initial Registrar, Paying Agent and Service Agent for each Series unless another Registrar, Paying Agent or Service Agent, as the case may be, is appointed prior to the time
Securities of that Series are first issued. 
  
 Section 2.5
Paying Agent to Hold Money in Trust. 
  
 The Company shall
require each Paying Agent other than the Trustee to agree in writing that the Paying Agent will hold in trust, for the benefit of Securityholders of any Series of Securities, or the Trustee, all money held by the Paying Agent for the payment of
principal of or interest on the Series of Securities, and will notify the Trustee of any default by the Company in making any such payment. While any such default continues, the Trustee may require a Paying Agent to pay all money held by it to the
Trustee. The Company at any time may require a Paying Agent to pay all money held by it to the Trustee. Upon payment over to the Trustee, the Paying Agent (if other than the Company or a Subsidiary) shall have no further liability for the money. If
the Company or a Subsidiary acts as Paying Agent, it shall segregate and hold in a separate trust fund for the benefit of Securityholders of any Series of Securities all money held by it as Paying Agent. 
  
 Section 2.6 Securityholder Lists. 
  
 The Trustee shall preserve in as current a form as is reasonably practicable
the most recent list available to it of the names and addresses of Securityholders of each Series of Securities and shall otherwise comply with TIA Section 312(a). If the Trustee is not the Registrar, the Company shall furnish to the Trustee at
least ten days before each interest payment date and at such other times as the Trustee may request in writing a list, in such form and as of such date as the Trustee may reasonably require, of the names and addresses of Securityholders of each
Series of Securities. 
  
 Section 2.7 Transfer and Exchange.

  
 Where Securities of a Series are presented to the
Registrar or a co-registrar with a request to register a transfer or to exchange them for an equal principal amount of Securities of the same Series, the Registrar shall register the transfer or make the exchange if its requirements for such
transactions are met. To permit registrations of transfers and exchanges, the Trustee shall authenticate Securities at the Registrar’s request. No service charge shall be made for any registration of transfer or exchange (except as otherwise
expressly permitted herein), but the Company may require payment of a sum sufficient to cover any transfer tax or similar governmental charge payable in connection therewith (other than any such transfer tax or similar governmental charge payable
upon exchanges pursuant to Sections 2.11, 3.6 or 9.6). 
  
 Neither
the Company nor the Registrar shall be required (a) to issue, register the transfer of, or exchange Securities of any Series for the period beginning at the opening of business fifteen days immediately preceding the mailing of a notice of redemption
of Securities of that Series selected for redemption and ending at the close of business on the day of such mailing, or 

  

 12. 

 
(b) to register the transfer of or exchange Securities of any Series selected, called or being called for redemption as a whole or the portion being redeemed
of any such Securities selected, called or being called for redemption in part. 
  
 Section 2.8 Mutilated, Destroyed, Lost and Stolen Securities. 
  
 If any mutilated Security is surrendered to the Trustee, the Company shall execute and the Trustee shall authenticate and deliver in exchange therefor a
new Security of the same Series and of like tenor and principal amount and bearing a number not contemporaneously outstanding. 
  
 If there shall be delivered to the Company and the Trustee (i) evidence to their satisfaction of the destruction, loss or theft of any Security and (ii)
such security or indemnity as may be required by them to save each of them and any agent of either of them harmless, then, in the absence of notice to the Company or the Trustee that such Security has been acquired by a bona fide purchaser, the
Company shall execute and upon its request the Trustee shall authenticate and make available for delivery, in lieu of any such destroyed, lost or stolen Security, a new Security of the same Series and of like tenor and principal amount and bearing a
number not contemporaneously outstanding. 
  
 In case any such
mutilated, destroyed, lost or stolen Security has become or is about to become due and payable, the Company in its discretion may, instead of issuing a new Security, pay such Security. 
  
 Upon the issuance of any new Security under this Section, the Company may require the payment of a sum sufficient to cover
any tax or other governmental charge that may be imposed in relation thereto and any other expenses (including the fees and expenses of the Trustee) connected therewith. 
  
 Every new Security of any Series issued pursuant to this Section in lieu of any destroyed, lost or stolen Security shall
constitute an original additional contractual obligation of the Company, whether or not the destroyed, lost or stolen Security shall be at any time enforceable by anyone, and shall be entitled to all the benefits of this Indenture equally and
proportionately with any and all other Securities of that Series duly issued hereunder. 
  
 The provisions of this Section are exclusive and shall preclude (to the extent lawful) all other rights and remedies with respect to the replacement or payment of mutilated, destroyed, lost or stolen Securities.

  
 Section 2.9 Outstanding Securities. 
  
 The Securities outstanding at any time are all the Securities authenticated
by the Trustee except for those canceled by it, those delivered to it for cancellation, those reductions in the interest on a Global Security effected by the Trustee in accordance with the provisions hereof and those described in this Section as not
outstanding. 
  

 13. 

 If a Security is replaced pursuant to Section 2.8, it ceases to be outstanding until the Trustee receives
proof satisfactory to it that the replaced Security is held by a bona fide purchaser. 
  
 If the Paying Agent (other than the Company, a Subsidiary or an Affiliate of any thereof) holds on the Maturity of Securities of a Series money sufficient to pay such Securities payable on that date, then on and after
that date such Securities of the Series cease to be outstanding and interest on them ceases to accrue. 
  
 A Security does not cease to be outstanding because the Company or an Affiliate holds the Security. 
  
 In determining whether the Holders of the requisite principal amount of
outstanding Securities have given any request, demand, authorization, direction, notice, consent or waiver hereunder, the principal amount of a Discount Security that shall be deemed to be outstanding for such purposes shall be the amount of the
principal thereof that would be due and payable as of the date of such determination upon a declaration of acceleration of the Maturity thereof pursuant to Section 6.2. 
  
 Section 2.10 Treasury Securities. 
  
 In determining whether the Holders of the required principal amount of Securities of a Series have concurred in any request,
demand, authorization, direction, notice, consent or waiver Securities of a Series owned by the Company or an Affiliate shall be disregarded, except that for the purposes of determining whether the Trustee shall be protected in relying on any such
request, demand, authorization, direction, notice, consent or waiver only Securities of a Series that the Trustee knows are so owned shall be so disregarded. 
  
 Section 2.11 Temporary Securities. 
  
 Until definitive Securities are ready for delivery, the Company may prepare and the Trustee shall authenticate temporary Securities upon a Company Order.
Temporary Securities shall be substantially in the form of definitive Securities but may have variations that the Company considers appropriate for temporary Securities. Without unreasonable delay, the Company shall prepare and the Trustee upon
request shall authenticate definitive Securities of the same Series and date of maturity in exchange for temporary Securities. Until so exchanged, temporary securities shall have the same rights under this Indenture as the definitive Securities.

  
 Section 2.12 Cancellation. 
  
 The Company at any time may deliver Securities to the Trustee for
cancellation. The Registrar and the Paying Agent shall forward to the Trustee any Securities surrendered to them for registration of transfer, exchange or payment. The Trustee shall cancel all Securities surrendered for transfer, exchange, payment,
replacement or cancellation and shall destroy such canceled Securities (subject to the record retention requirement of the Exchange Act) and deliver a certificate of such destruction to the Company, unless the Company otherwise directs. The Company
may not issue new Securities to replace Securities that it has paid or delivered to the Trustee for cancellation. 
  

 14. 

 Section 2.13 Defaulted Interest. 
  
 If the Company defaults in a payment of interest on a Series of Securities, it shall pay the defaulted interest, plus, to
the extent permitted by law, any interest payable on the defaulted interest, to the persons who are Securityholders of the Series on a subsequent special record date. The Company shall fix the record date and payment date. At least 30 days before
the record date, the Company shall mail to the Trustee and to each Securityholder of the Series a notice that states the record date, the payment date and the amount of interest to be paid. The Company may pay defaulted interest in any other lawful
manner. 
  
 Section 2.14 Global Securities. 
  
 2.14.1 Terms of Securities. A Board
Resolution, a supplemental indenture hereto or an Officers’ Certificate shall establish whether the Securities of a Series shall be issued in whole or in part in the form of one or more Global Securities and the Depository for such Global
Security or Securities. 
  
 2.14.2
Transfer and Exchange. Notwithstanding any provisions to the contrary contained in Section 2.7 of the Indenture and in addition thereto, any Global Security shall be exchangeable pursuant to Section 2.7 of the Indenture for Securities
registered in the names of Holders other than the Depository for such Security or its nominee only if (i) such Depository notifies the Company that it is unwilling or unable to continue as Depository for such Global Security or if at any time such
Depository ceases to be a clearing agency registered under the Exchange Act, and, in either case, the Company fails to appoint a successor Depository within 90 days of such event, (ii) the Company executes and delivers to the Trustee an
Officers’ Certificate to the effect that such Global Security shall be so exchangeable or (iii) an Event of Default with respect to the Securities represented by such Global Security shall have happened and be continuing. Any Global Security
that is exchangeable pursuant to the preceding sentence shall be exchangeable for Securities registered in such names as the Depository shall direct in writing in an aggregate principal amount equal to the principal amount of the Global Security
with like tenor and terms. 
  
 Except as provided
in this Section 2.14.2, a Global Security may not be transferred except as a whole by the Depository with respect to such Global Security to a nominee of such Depository, by a nominee of such Depository to such Depository or another nominee of such
Depository or by the Depository or any such nominee to a successor Depository or a nominee of such a successor Depository. 
  
 2.14.3 Legend. Unless otherwise provided pursuant to Section 2.2, any Global Security issued hereunder shall bear a legend
in substantially the following form: 
  
 “This Security is a Global Security within the meaning of the Indenture hereinafter referred to and is registered in the name of the Depository or a nominee of the Depository. This Security is exchangeable for Securities registered in
the name of a person other than the Depository or its nominee only in the limited circumstances described in the Indenture, and may not be transferred except as a whole by the Depository to a nominee of the Depository, by a nominee of the Depository
to the Depository or another nominee of the Depository or by the 

  

 15. 

 
Depository or any such nominee to a successor Depository or a nominee of such a successor Depository.” 
  
 2.14.4 Acts of Holders. The Depository, as a
Holder, may appoint agents and otherwise authorize participants to give or take any request, demand, authorization, direction, notice, consent, waiver or other action which a Holder is entitled to give or take under the Indenture. 
  
 2.14.5 Payments. Notwithstanding the other
provisions of this Indenture, unless otherwise specified as contemplated by Section 2.2, payment of the principal of, premium, if any, and interest, if any, on any Global Security shall be made to the Holder thereof. 
  
 2.14.6 Consents, Declaration and Directions.
Except as provided in Section 2.14.5, the Company, the Trustee and any Agent shall treat a person as the Holder of such principal amount of outstanding Securities of such Series represented by a Global Security as shall be specified in a written
statement of the Depositary with respect to such Global Security, for purposes of obtaining any consents, declarations, waivers or directions required to be given by the Holders pursuant to this Indenture. 
  
 Section 2.15 CUSIP Numbers. 
  
 The Company in issuing the Securities may use “CUSIP” numbers (if
then generally in use), and, if so, the Trustee shall use “CUSIP” numbers in notices of redemption as a convenience to Holders; provided that any such notice may state that no representation is made as to the correctness of such numbers
either as printed on the Securities or as contained in any notice of a redemption and that reliance may be placed only on the other elements of identification printed on the Securities, and any such redemption shall not be affected by any defect in
or omission of such numbers. 
  
 ARTICLE 3 
  
 REDEMPTION 
  
 Section 3.1 Notice to Trustee. 
  
 The Company may, with respect to any Series of Securities, reserve the right
to redeem and pay the Series of Securities or may covenant to redeem and pay the Series of Securities or any part thereof prior to the Stated Maturity thereof at such time and on such terms as provided for in such Securities. If a Series of
Securities is redeemable and the Company wants or is obligated to redeem prior to the Stated Maturity thereof all or part of the Series of Securities pursuant to the terms of such Securities, it shall notify the Trustee of the redemption date and
the principal amount of Series of Securities to be redeemed. The Company shall give the notice at least 45 days before the redemption date (or such shorter notice as may be acceptable to the Trustee). 
  

 16. 

 Section 3.2 Selection of Securities to be Redeemed. 
  
 Unless otherwise indicated for a particular Series by a Board Resolution, a
supplemental indenture or an Officers’ Certificate, if less than all the Securities of a Series are to be redeemed, the Trustee shall select the Securities of the Series to be redeemed in any manner that the Trustee deems fair and appropriate.
The Trustee shall make the selection from Securities of the Series outstanding not previously called for redemption. The Trustee may select for redemption portions of the principal of Securities of the Series that have denominations larger than
$1,000. Securities of the Series and portions of them it selects shall be in amounts of $1,000 or whole multiples of $1,000 or, with respect to Securities of any Series issuable in other denominations pursuant to Section 2.2.10, the minimum
principal denomination for each Series and integral multiples thereof. Provisions of this Indenture that apply to Securities of a Series called for redemption also apply to portions of Securities of that Series called for redemption. 
  
 Section 3.3 Notice of Redemption. 
  
 Unless otherwise indicated for a particular Series by Board Resolution, a
supplemental indenture hereto or an Officers’ Certificate, at least 30 days but not more than 90 days before a redemption date, the Company shall mail a notice of redemption by first-class mail to each Holder whose Securities are to be redeemed
and if any Bearer Securities are outstanding, publish on one occasion a notice in an Authorized Newspaper. 
  
 The notice shall identify the Securities of the Series to be redeemed and shall state: 
  
 (a) the redemption date; 
  
 (b) the redemption price; 
  
 (c) the name and address of the Paying Agent; 
  
 (d) that Securities of the Series called for
redemption must be surrendered to the Paying Agent to collect the redemption price; 
  
 (e) that interest on Securities of the Series called for redemption ceases to accrue on and after the redemption date; and

  
 (f) any other information as may be
required by the terms of the particular Series or the Securities of a Series being redeemed. 
  
 At the Company’s request, the Trustee shall give the notice of redemption in the Company’s name and at its expense. 
  
 Section 3.4 Effect of Notice of Redemption. 
  
 Once notice of redemption is mailed or published as provided in Section 3.3, Securities of a Series called for redemption become due and payable on the
redemption date and at the redemption price. A notice of redemption may not be conditional. Upon surrender to the Paying 

  

 17. 

 
Agent, such Securities shall be paid at the redemption price plus accrued interest to the redemption date. 
  
 Section 3.5 Deposit of Redemption Price. 
  
 On or before the redemption date, the Company shall deposit with the Paying
Agent money sufficient to pay the redemption price of and accrued interest, if any, on all Securities to be redeemed on that date. 
  
 Section 3.6 Securities Redeemed in Part. 
  
 Upon surrender of a Security that is redeemed in part, the Trustee shall authenticate for the Holder a new Security of the same Series and the same
maturity equal in principal amount to the unredeemed portion of the Security surrendered. 
  
 ARTICLE 4 
  
 COVENANTS

  
 Section 4.1 Payment of Principal and Interest.

  
 The Company covenants and agrees for the benefit of the
Holders of each Series of Securities that it will duly and punctually pay the principal of and interest, if any, on the Securities of that Series in accordance with the terms of such Securities and this Indenture. 
  
 Section 4.2 SEC Reports. 
  
 The Company shall deliver to the Trustee after it files them with the SEC
copies of the annual reports and of the information, documents, and other reports (or copies of such portions of any of the foregoing as the SEC may by rules and regulations prescribe) which the Company is required to file with the SEC pursuant to
Section 13 or 15(d) of the Exchange Act. The Company also shall comply with the other provisions of TIA Section 314(a). 
  
 Section 4.3 Compliance Certificate. 
  
 The Company shall deliver to the Trustee, within 120 days after the end of each fiscal year of the Company, an Officers’ Certificate stating that a
review of the activities of the Company and its Subsidiaries during the preceding fiscal year has been made under the supervision of the signing Officers with a view to determining whether the Company has kept, observed, performed and fulfilled its
obligations under this Indenture, and further stating, as to each such Officer signing such certificate, that to the best of his knowledge the Company has kept, observed, performed and fulfilled each and every covenant contained in this Indenture
and is not in default in the performance or observance of any of the terms, provisions and conditions hereof (or, if a Default or Event of Default shall have occurred, describing all such Defaults or Events of Default of which he may have
knowledge). 
  
 The Company will, so long as any of the Securities
are outstanding, deliver to the Trustee, forthwith upon becoming aware of any Default or Event of Default, an Officers’ 

  

 18. 

 
Certificate specifying such Default or Event of Default and what action the Company is taking or proposes to take with respect thereto. 
  
 Section 4.4 Corporate Existence. 
  
 Subject to Article V, the Company will do or cause to be done all things
necessary to preserve and keep in full force and effect its corporate existence and the rights (charter and statutory), licenses and franchises of the Company; provided, however, that the Company shall not be required to preserve any such right,
license or franchise, if the Board of Directors shall determine that the preservation thereof is no longer desirable in the conduct of the business of the Company and its Subsidiaries taken as a whole and that the loss thereof is not adverse in any
material respect to the Holders. 
  
 Section 4.5 Taxes.

  
 The Company shall pay prior to delinquency all taxes,
assessments and governmental levies, except as contested in good faith and by appropriate proceedings. 
  
 ARTICLE 5 
  
 SUCCESSORS 
  
 Section 5.1 When Company May
Merge, Etc. 
  
 The Company shall not consolidate with or
merge into, or convey, transfer or lease all or substantially all of its properties and assets to, any person (a “successor person”), and may not permit any person to merge into, or convey, transfer or lease its properties and assets
substantially as an entirety to, the Company, unless: 
  
 (a) the successor person (if any) is a corporation, partnership, trust or other entity organized and validly existing under the laws of any U.S. domestic jurisdiction and expressly assumes the Company’s obligations on the
Securities and under this Indenture and 
  
 (b) immediately after giving effect to the transaction, no Default or Event of Default, shall have occurred and be continuing. 
  
 The Company shall deliver to the Trustee prior to the consummation of the proposed transaction an Officers’ Certificate to the foregoing effect and
an Opinion of Counsel stating that the proposed transaction and such supplemental indenture comply with this Indenture. 
  
 Section 5.2 Successor Corporation Substituted. 
  
 Upon any consolidation or merger, or any sale, lease, conveyance or other disposition of all or substantially all of the assets of the Company in
accordance with Section 5.1, the successor corporation formed by such consolidation or into or with which the Company is merged or to which such sale, lease, conveyance or other disposition is made shall succeed to, and be substituted for, and may
exercise every right and power of, the Company under this Indenture with the same effect as if such successor person has been named as the Company herein; 

  

 19. 

 
provided, however, that the predecessor Company in the case of a sale, lease, conveyance or other disposition shall not be released from the obligation to
pay the principal of and interest, if any, on the Securities. 
  
 ARTICLE 6 
  
 DEFAULTS AND REMEDIES

  
 Section 6.1 Events of Default. 
  
 “Event of Default,” wherever used herein with respect to
Securities of any Series, means any one of the following events, unless in the establishing Board Resolution, supplemental indenture or Officers’ Certificate, it is provided that such Series shall not have the benefit of said Event of Default:

  
 (a) default in the payment of any
interest on any Security of that Series when it becomes due and payable, and continuance of such default for a period of 90 days (unless the entire amount of such payment is deposited by the Company with the Trustee or with a Paying Agent prior to
the expiration of such period of 90 days); or 
  
 (b) default in the payment of the principal of any Security of that Series at its Maturity; or 
  
 (c) default in the deposit of any sinking fund payment, when and as due in respect of any Security of that Series; or 

 
 (d) default in the performance or breach of any
covenant or warranty of the Company in this Indenture (other than a covenant or warranty that has been included in this Indenture solely for the benefit of Series of Securities other than that Series), which default continues uncured for a period of
90 days after there has been given, by registered or certified mail, to the Company by the Trustee or to the Company and the Trustee by the Holders of at least 25% in principal amount of the outstanding Securities of that Series a written notice
specifying such default or breach and requiring it to be remedied and stating that such notice is a “Notice of Default” hereunder; or 
  
 (e) the Company pursuant to or within the meaning of any Bankruptcy Law: 
  
 (i) commences a voluntary case, 
  
 (ii) consents to the entry of an order for relief
against it in an involuntary case, 
  
 (iii)
consents to the appointment of a Custodian of it or for all or substantially all of its property, 
  
 (iv) makes a general assignment for the benefit of its creditors, or 
  

 20. 

 (v) generally is unable to pay its debts as the same become due; or 
  
 (f) a court of competent jurisdiction enters an order
or decree under any Bankruptcy Law that: 
  
 (i) is for relief against the Company in an involuntary case, 
  
 (ii) appoints a Custodian for the Company or for all or substantially all of its property, or 
  
 (iii) orders the liquidation of the Company and the order or decree remains unstayed and in effect for 90 days; or 
  
 (g) any other Event of Default provided with respect
to Securities of that Series, which is specified in a Board Resolution, a supplemental indenture hereto or an Officers’ Certificate, in accordance with Section 2.2.19. 
  
 The term “Bankruptcy Law” means title 11, U.S. Code or any similar Federal or State law for the relief of debtors.
The term “Custodian” means any receiver, trustee, assignee, liquidator or similar official under any Bankruptcy Law. 
  
 Section 6.2 Acceleration of Maturity; Rescission and Annulment. 
  
 If an Event of Default with respect to Securities of any Series at the time outstanding occurs and is continuing (other than
an Event of Default referred to in Section 6.1(e) or (f) ) then in every such case the Trustee or the Holders of not less than 25% in principal amount of the outstanding Securities of that Series may declare the principal amount (or, if any
Securities of that Series are Discount Securities, such portion of the principal amount as may be specified in the terms of such Securities) of and accrued and unpaid interest, if any, on all of the Securities of that Series to be due and payable
immediately, by a notice in writing to the Company (and to the Trustee if given by Holders), and upon any such declaration such principal amount (or specified amount) and accrued and unpaid interest, if any, shall become immediately due and payable.
If an Event of Default specified in Section 6.1(e) or (f) shall occur, the principal amount (or specified amount) of and accrued and unpaid interest, if any, on all outstanding Securities shall ipso facto become and be immediately due and payable
without any declaration or other act on the part of the Trustee or any Holder. 
  
 At any time after such a declaration of acceleration with respect to any Series has been made and before a judgment or decree for payment of the money due has been obtained by the Trustee as hereinafter in this
Article provided, the Holders of a majority in principal amount of the outstanding Securities of that Series, by written notice to the Company and the Trustee, may rescind and annul such declaration and its consequences if: 
  
 (a) the Company has paid or deposited with the
Trustee a sum sufficient to pay 
  
 (i)
all overdue interest, if any, on all Securities of that Series, 
  

 21. 

 (ii) the principal of any Securities of that Series which have become due
otherwise than by such declaration of acceleration and interest thereon at the rate or rates prescribed therefor in such Securities, 
  
 (iii) to the extent that payment of such interest is lawful, interest upon any overdue principal and overdue interest at the rate
or rates prescribed therefor in such Securities, and 
  
 (iv) all sums paid or advanced by the Trustee hereunder and the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel; and 
  
 (b) all Events of Default with respect to Securities of that Series, other than the non-payment of
the principal of Securities of that Series which have become due solely by such declaration of acceleration, have been cured or waived as provided in Section 6.13. 
  
 No such rescission shall affect any subsequent Default or impair any right consequent thereon. 
  
 Section 6.3 Collection of Indebtedness and Suits for Enforcement by
Trustee. 
  
 The Company covenants that if 
  
 (a) default is made in the payment of any interest on
any Security when such interest becomes due and payable and such default continues for a period of 90 days, or 
  
 (b) default is made in the payment of principal of any Security at the Maturity thereof, or 
  
 (c) default is made in the deposit of any sinking
fund payment when and as due by the terms of a Security, then, the Company will, upon demand of the Trustee, pay to it, for the benefit of the Holders of such Securities, the whole amount then due and payable on such Securities for principal and
interest and, to the extent that payment of such interest shall be legally enforceable, interest on any overdue principal or any overdue interest, at the rate or rates prescribed therefor in such Securities, and, in addition thereto, such further
amount as shall be sufficient to cover the costs and expenses of collection, including the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel. 
  
 If the Company fails to pay such amounts forthwith upon such demand, the
Trustee, in its own name and as trustee of an express trust, may institute a judicial proceeding for the collection of the sums so due and unpaid, may prosecute such proceeding to judgment or final decree and may enforce the same against the Company
or any other obligor upon such Securities and collect the moneys adjudged or deemed to be payable in the manner provided by law out of the property of the Company or any other obligor upon such Securities, wherever situated. 
  
 If an Event of Default with respect to any Securities of any Series occurs
and is continuing, the Trustee may in its discretion proceed to protect and enforce its rights and the 

  

 22. 

 
rights of the Holders of Securities of such Series by such appropriate judicial proceedings as the Trustee shall deem most effectual to protect and enforce
any such rights, whether for the specific enforcement of any covenant or agreement in this Indenture or in aid of the exercise of any power granted herein, or to enforce any other proper remedy. 
  
 Section 6.4 Trustee May File Proofs of Claim. 
  
 In case of the pendency of any receivership, insolvency, liquidation,
bankruptcy, reorganization, arrangement, adjustment, composition or other judicial proceeding relative to the Company or any other obligor upon the Securities or the property of the Company or of such other obligor or their creditors, the Trustee
(irrespective of whether the principal of the Securities shall then be due and payable as therein expressed or by declaration or otherwise and irrespective of whether the Trustee shall have made any demand on the Company for the payment of overdue
principal or interest) shall be entitled and empowered, by intervention in such proceeding or otherwise, 
  
 (a) to file and prove a claim for the whole amount of principal and interest owing and unpaid in respect of the Securities and to
file such other papers or documents as may be necessary or advisable in order to have the claims of the Trustee (including any claim for the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel) and of
the Holders allowed in such judicial proceeding, and 
  
 (b) to collect and receive any moneys or other property payable or deliverable on any such claims and to distribute the same, and any custodian, receiver, assignee, trustee, liquidator, sequestrator or other similar official in any
such judicial proceeding is hereby authorized by each Holder to make such payments to the Trustee and, in the event that the Trustee shall consent to the making of such payments directly to the Holders, to pay to the Trustee any amount due it for
the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, and any other amounts due the Trustee under Section 7.7. 
  
 Nothing herein contained shall be deemed to authorize the Trustee to authorize or consent to or accept or adopt on behalf of
any Holder any plan of reorganization, arrangement, adjustment or composition affecting the Securities or the rights of any Holder thereof or to authorize the Trustee to vote in respect of the claim of any Holder in any such proceeding. 

 
 Section 6.5 Trustee May Enforce Claims Without Possession of
Securities. 
  
 All rights of action and claims under this
Indenture or the Securities may be prosecuted and enforced by the Trustee without the possession of any of the Securities or the production thereof in any proceeding relating thereto, and any such proceeding instituted by the Trustee shall be
brought in its own name as trustee of an express trust, and any recovery of judgment shall, after provision for the payment of the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, be for the
ratable benefit of the Holders of the Securities in respect of which such judgment has been recovered. 
  

 23. 

 Section 6.6 Application of Money Collected. 
  
 Any money collected by the Trustee pursuant to this Article shall be applied
in the following order, at the date or dates fixed by the Trustee and, in case of the distribution of such money on account of principal or interest, upon presentation of the Securities and the notation thereon of the payment if only partially paid
and upon surrender thereof if fully paid: 
  
 First: To the
payment of all amounts due the Trustee under Section 7.7; and 
  
 Second: To the payment of the amounts then due and unpaid for principal of and interest on the Securities in respect of which or for the benefit of which such money has been collected, ratably, without preference or priority of any kind,
according to the amounts due and payable on such Securities for principal and interest, respectively; and 
  
 Third: To the Company. 
  
 Section 6.7 Limitation on Suits. 
  
 No Holder of any Security of any Series shall have any right to institute any proceeding, judicial or otherwise, with respect to this Indenture, or for
the appointment of a receiver or trustee, or for any other remedy hereunder, unless 
  
 (a) such Holder has previously given written notice to the Trustee of a continuing Event of Default with respect to the Securities
of that Series; 
  
 (b) the Holders of not
less than 25% in principal amount of the outstanding Securities of that Series shall have made written request to the Trustee to institute proceedings in respect of such Event of Default in its own name as Trustee hereunder; 
  
 (c) such Holder or Holders have offered to the
Trustee reasonable indemnity against the costs, expenses and liabilities to be incurred in compliance with such request; 
  
 (d) the Trustee for 90 days after its receipt of such notice, request and offer of indemnity has failed to institute any such
proceeding; and 
  
 (e) no direction
inconsistent with such written request has been given to the Trustee during such 90-day period by the Holders of a majority in principal amount of the outstanding Securities of that Series; it being understood and intended that no one or more of
such Holders shall have any right in any manner whatever by virtue of, or by availing of, any provision of this Indenture to affect, disturb or prejudice the rights of any other of such Holders, or to obtain or to seek to obtain priority or
preference over any other of such Holders or to enforce any right under this Indenture, except in the manner herein provided and for the equal and ratable benefit of all such Holders. 
  

 24. 

 Section 6.8 Unconditional Right of Holders to Receive Principal and Interest. 
  
 Notwithstanding any other provision in this Indenture, the Holder of any
Security shall have the right, which is absolute and unconditional, to receive payment of the principal of and interest, if any, on such Security on the Stated Maturity or Stated Maturities expressed in such Security (or, in the case of redemption,
on the redemption date) and to institute suit for the enforcement of any such payment, and such rights shall not be impaired without the consent of such Holder. 
  

Section 6.9 Restoration of Rights and Remedies. 
  
 If the Trustee or any Holder has instituted any proceeding to enforce any right or remedy under this Indenture and such proceeding has been discontinued
or abandoned for any reason, or has been determined adversely to the Trustee or to such Holder, then and in every such case, subject to any determination in such proceeding, the Company, the Trustee and the Holders shall be restored severally and
respectively to their former positions hereunder and thereafter all rights and remedies of the Trustee and the Holders shall continue as though no such proceeding had been instituted. 
  
 Section 6.10 Rights and Remedies Cumulative. 
  
 Except as otherwise provided with respect to the replacement or payment of mutilated, destroyed, lost or stolen Securities
in Section 2.8, no right or remedy herein conferred upon or reserved to the Trustee or to the Holders is intended to be exclusive of any other right or remedy, and every right and remedy shall, to the extent permitted by law, be cumulative and in
addition to every other right and remedy given hereunder or now or hereafter existing at law or in equity or otherwise. The assertion or employment of any right or remedy hereunder, or otherwise, shall not prevent the concurrent assertion or
employment of any other appropriate right or remedy. 
  
 Section 6.11 Delay or Omission Not Waiver. 
  
 No
delay or omission of the Trustee or of any Holder of any Securities to exercise any right or remedy accruing upon any Event of Default shall impair any such right or remedy or constitute a waiver of any such Event of Default or an acquiescence
therein. Every right and remedy given by this Article or by law to the Trustee or to the Holders may be exercised from time to time, and as often as may be deemed expedient, by the Trustee or by the Holders, as the case may be. 
  
 Section 6.12 Control by Holders. 
  
 The Holders of a majority in principal amount of the outstanding Securities
of any Series shall have the right to direct the time, method and place of conducting any proceeding for any remedy available to the Trustee, or exercising any trust or power conferred on the Trustee, with respect to the Securities of such Series,
provided that 
  
 (a) such direction shall
not be in conflict with any rule of law or with this Indenture, 
  

 25. 

 (b) the Trustee may take any other action deemed proper by the Trustee which is
not inconsistent with such direction, and 
  
 (c) subject to the provisions of Section 6.1, the Trustee shall have the right to decline to follow any such direction if the Trustee in good faith shall, by a Responsible Officer of the Trustee, determine that the proceeding so
directed would involve the Trustee in personal liability. 
  
 Section 6.13 Waiver of Past Defaults. 
  
 Subject
to Section 6.2, the Holders of not less than a majority in principal amount of the outstanding Securities of any Series may on behalf of the Holders of all the Securities of such Series waive any past Default hereunder with respect to such Series
and its consequences, except a Default in the payment of the principal of or interest on any Security of such Series (provided, however, that the Holders of a majority in principal amount of the outstanding Securities of any Series may rescind an
acceleration and its consequences, including any related payment default that resulted from such acceleration). Upon any such waiver, such Default shall cease to exist, and any Event of Default arising therefrom shall be deemed to have been cured,
for every purpose of this Indenture; but no such waiver shall extend to any subsequent or other Default or impair any right consequent thereon. 
  
 Section 6.14 Undertaking for Costs. 
  
 All parties to this Indenture agree, and each Holder of any Security by his acceptance thereof shall be deemed to have agreed, that any court may in its
discretion require, in any suit for the enforcement of any right or remedy under this Indenture, or in any suit against the Trustee for any action taken, suffered or omitted by it as Trustee, the filing by any party litigant in such suit of an
undertaking to pay the costs of such suit, and that such court may in its discretion assess reasonable costs, including reasonable attorneys’ fees, against any party litigant in such suit, having due regard to the merits and good faith of the
claims or defenses made by such party litigant; but the provisions of this Section shall not apply to any suit instituted by the Company, to any suit instituted by the Trustee, to any suit instituted by any Holder, or group of Holders, holding in
the aggregate more than 10% in principal amount of the outstanding Securities of any Series, or to any suit instituted by any Holder for the enforcement of the payment of the principal of or interest on any Security on or after the Stated Maturity
or Stated Maturities expressed in such Security (or, in the case of redemption, on the redemption date). 
  
 ARTICLE 7 
  
 TRUSTEE 
  
 Section 7.1 Duties of Trustee.

  
 (a) If an Event of Default has
occurred and is continuing, the Trustee shall exercise the rights and powers vested in it by this Indenture and use the same degree of care and skill in their exercise as a prudent man would exercise or use under the circumstances in the conduct of
his own affairs. 
  

 26. 

 (b) Except during the continuance of an Event of Default: 
  
 (i) The Trustee need perform only those duties that
are specifically set forth in this Indenture and no others. 
  
 (ii) In the absence of bad faith on its part, the Trustee may conclusively rely, as to the truth of the statements and the correctness of the opinions expressed therein, upon Officers’ Certificates or
Opinions of Counsel furnished to the Trustee and conforming to the requirements of this Indenture; however, in the case of any such Officers’ Certificates or Opinions of Counsel which by any provisions hereof are specifically required to be
furnished to the Trustee, the Trustee shall examine such Officers’ Certificates and Opinions of Counsel to determine whether or not they conform to the requirements of this Indenture. 
  
 (c) The Trustee may not be relieved from liability
for its own negligent action, its own negligent failure to act or its own willful misconduct, except that: 
  
 (i) This paragraph does not limit the effect of paragraph (b) of this Section. 
  
 (ii) The Trustee shall not be liable for any error of
judgment made in good faith by a Responsible Officer, unless it is proved that the Trustee was negligent in ascertaining the pertinent facts. 
  
 (iii) The Trustee shall not be liable with respect to any action taken, suffered or omitted to be taken by it with respect to
Securities of any Series in good faith in accordance with the direction of the Holders of a majority in principal amount of the outstanding Securities of such Series relating to the time, method and place of conducting any proceeding for any remedy
available to the Trustee, or exercising any trust or power conferred upon the Trustee, under this Indenture with respect to the Securities of such Series. 
  
 (d) Every provision of this Indenture that in any way relates to the Trustee is subject to paragraph (a), (b) and (c) of this
Section. 
  
 (e) The Trustee may refuse to
perform any duty or exercise any right or power unless it receives indemnity satisfactory to it against any loss, liability or expense. 
  
 (f) The Trustee shall not be liable for interest on any money received by it except as the Trustee may agree in writing with the
Company. Money held in trust by the Trustee need not be segregated from other funds except to the extent required by law. 
  
 (g) No provision of this Indenture shall require the Trustee to risk its own funds or otherwise incur any financial liability in
the performance of any of its duties, or in the exercise of any of its rights or powers, if it shall have reasonable grounds for believing that repayment of such funds or adequate indemnity against such risk is not reasonably assured to it.

  
 (h) The Paying Agent, the Registrar
and any authenticating agent shall be entitled to the protections and immunities as are set forth in paragraphs (a), (b) and (c) of this Section with respect to the Trustee. 
  

 27. 

 Section 7.2 Rights of Trustee. 
  
 (a) The Trustee may rely on and shall be protected in acting or refraining from acting upon any
document believed by it to be genuine and to have been signed or presented by the proper person. The Trustee need not investigate any fact or matter stated in the document. 
  
 (b) Before the Trustee acts or refrains from acting, it may require an Officers’ Certificate or
an Opinion of Counsel. The Trustee shall not be liable for any action it takes or omits to take in good faith in reliance on such Officers’ Certificate or Opinion of Counsel. 
  
 (c) The Trustee may act through agents and shall not be responsible for the misconduct or negligence
of any agent appointed with due care. No Depository shall be deemed an agent of the Trustee and the Trustee shall not be responsible for any act or omission by any Depository. 
  
 (d) The Trustee shall not be liable for any action it takes or omits to take in good faith which it
believes to be authorized or within its rights or powers. 
  
 (e) The Trustee may consult with counsel and the advice of such counsel or any Opinion of Counsel shall be full and complete authorization and protection in respect of any action taken, suffered or omitted by
it hereunder in good faith and in reliance thereon. 
  
 (f) The Trustee shall be under no obligation to exercise any of the rights or powers vested in it by this Indenture at the request or direction of any of the Holders of Securities unless such Holders shall have offered to the Trustee
reasonable security or indemnity against the costs, expenses and liabilities which might be incurred by it in compliance with such request or direction. 
  
 In addition, the Trustee shall not be deemed to have knowledge of any Default or Event of Default except (1) any Event of Default occurring pursuant to
Sections 6.1(a)(1), 6.1(a)(2), 6.1(a)(3) and 4.1 hereof or (2) any Default or Event of Default of which the Trustee shall have received written notification in the manner set forth in this Indenture or a Responsible Officer of the Trustee shall have
obtained actual knowledge. Delivery of reports, information and documents to the Trustee under Section 4.2 is for informational purposes only and the information and the Trustee’s receipt of the foregoing shall not constitute constructive
notice of any information contained therein, or determinable from information contained therein including the Company’s compliance with any of their covenants thereunder (as to which the Trustee is entitled to rely exclusively on an
Officers’ Certificate). 
  
 Section 7.3 Individual Rights
of Trustee. 
  
 The Trustee in its individual or any other
capacity may become the owner or pledgee of Securities and may otherwise deal with the Company or an Affiliate with the same rights it would have if it were not Trustee. Any Agent may do the same with like rights. The Trustee is also subject to
Sections 7.10 and 7.11. 
  

 28. 

 Section 7.4 Trustee’s Disclaimer. 
  
 The Trustee makes no representation as to the validity or adequacy of this
Indenture or the Securities, it shall not be accountable for the Company’s use of the proceeds from the Securities, and it shall not be responsible for any statement in the Securities other than its authentication. 
  
 Section 7.5 Notice of Defaults. 
  
 If a Default or Event of Default occurs and is continuing with respect to
the Securities of any Series and if it is known to a Responsible Officer of the Trustee, the Trustee shall mail to each Securityholder of the Securities of that Series and, if any Bearer Securities are outstanding, publish on one occasion in an
Authorized Newspaper, notice of a Default or Event of Default within 90 days after it occurs or, if later, after a Responsible Officer of the Trustee has knowledge of such Default or Event of Default. Except in the case of a Default or Event of
Default in payment of principal of or interest on any Security of any Series, the Trustee may withhold the notice if and so long as its corporate trust committee or a committee of its Responsible Officers in good faith determines that withholding
the notice is in the interests of Securityholders of that Series. 
  
 Section 7.6 Reports by Trustee to Holders. 
  
 Within 60 days after May 15 in each year, the Trustee shall transmit by mail to all Securityholders, as their names and addresses appear on the register kept by the Registrar and, if any Bearer Securities are outstanding, publish in an
Authorized Newspaper, a brief report dated as of such May 15, in accordance with, and to the extent required under, TIA Section 313. 
  
 A copy of each report at the time of its mailing to Securityholders of any Series shall be filed with the SEC and each stock exchange on which the
Securities of that Series are listed. The Company shall promptly notify the Trustee when Securities of any Series are listed on any stock exchange. 
  
 Section 7.7 Compensation and Indemnity. 
  
 The Company shall pay to the Trustee from time to time reasonable compensation for its services. The Trustee’s compensation shall not be limited by
any law on compensation of a trustee of an express trust. The Company shall reimburse the Trustee upon request for all reasonable out-of-pocket expenses incurred by it. Such expenses shall include the reasonable compensation and expenses of the
Trustee’s agents and counsel. 
  
 The Company shall indemnify
the Trustee (including the cost of defending itself) against any loss, liability or expense incurred by it except as set forth in the next paragraph in the performance of its duties under this Indenture as Trustee or Agent. The Trustee shall notify
the Company promptly of any claim for which it may seek indemnity. The Company shall defend the claim and the Trustee shall cooperate in the defense. The Trustee may have separate counsel and the Company shall pay the reasonable fees and expenses of
such counsel. The Company need not pay for any settlement made without its consent, which consent shall not be 

  

 29. 

 
unreasonably withheld. This indemnification shall apply to officers, directors, employees, shareholders and agents of the Trustee. 
  
 The Company need not reimburse any expense or indemnify against any loss or
liability incurred by the Trustee or by any officer, director, employee, shareholder or agent of the Trustee through negligence or bad faith. 
  
 To secure the Company’s payment obligations in this Section, the Trustee shall have a lien prior to the Securities of any Series on all money or
property held or collected by the Trustee, except that held in trust to pay principal and interest on particular Securities of that Series. 
  
 When the Trustee incurs expenses or renders services after an Event of Default specified in Section 6.1(e) or (f) occurs, the expenses and the
compensation for the services are intended to constitute expenses of administration under any Bankruptcy Law. 
  
 Section 7.8 Replacement of Trustee. 
  
 A resignation or removal of the Trustee and appointment of a successor Trustee shall become effective only upon the successor Trustee’s acceptance of
appointment as provided in this Section. 
  
 The Trustee may
resign with respect to the Securities of one or more Series by so notifying the Company. The Holders of a majority in principal amount of the Securities of any Series may remove the Trustee with respect to that Series by so notifying the Trustee and
the Company. The Company may remove the Trustee with respect to Securities of one or more Series if: 
  
 (a) the Trustee fails to comply with Section 7.10; 
  
 (b) the Trustee is adjudged a bankrupt or an insolvent or an order for relief is entered with respect
to the Trustee under any Bankruptcy Law; 
  
 (c) a Custodian or public officer takes charge of the Trustee or its property; or 
  
 (d) the Trustee becomes incapable of acting. 
  
 If the Trustee resigns or is removed or if a vacancy exists in the office of Trustee for any reason, the Company shall
promptly appoint a successor Trustee. Within one year after the successor Trustee takes office, the Holders of a majority in principal amount of the then outstanding Securities may appoint a successor Trustee to replace the successor Trustee
appointed by the Company. 
  
 If a successor Trustee with respect
to the Securities of any one or more Series does not take office within 30 days after the retiring Trustee resigns or is removed, the retiring Trustee, the Company or the Holders of at least 10% in principal amount of the Securities of the 

  

 30. 

 
applicable Series may petition any court of competent jurisdiction for the appointment of a successor Trustee. 
  
 If the Trustee with respect to the Securities of any one or more Series fails
to comply with Section 7.10, any Securityholder of the applicable Series may petition any court of competent jurisdiction for the removal of the Trustee and the appointment of a successor Trustee. 
  
 A successor Trustee shall deliver a written acceptance of its appointment to
the retiring Trustee and to the Company. Immediately after that, the retiring Trustee shall transfer all property held by it as Trustee to the successor Trustee subject to the lien provided for in Section 7.7, the resignation or removal of the
retiring Trustee shall become effective, and the successor Trustee shall have all the rights, powers and duties of the Trustee with respect to each Series of Securities for which it is acting as Trustee under this Indenture. A successor Trustee
shall mail a notice of its succession to each Securityholder of each such Series and, if any Bearer Securities are outstanding, publish such notice on one occasion in an Authorized Newspaper. Notwithstanding replacement of the Trustee pursuant to
this Section 7.8, the Company’s obligations under Section 7.7 hereof shall continue for the benefit of the retiring trustee with respect to expenses and liabilities incurred by it prior to such replacement. 
  
 Section 7.9 Successor Trustee by Merger, etc. 
  
 If the Trustee consolidates with, merges or converts into, or transfers all
or substantially all of its corporate trust business to, another corporation, the successor corporation without any further act shall be the successor Trustee. 
  

Section 7.10 Eligibility; Disqualification. 
  
 This Indenture shall always have a Trustee who satisfies the requirements of TIA Section 310(a) (1), (2) and (5). The Trustee shall always have a combined
capital and surplus of at least $25,000,000 as set forth in its most recent published annual report of condition. The Trustee shall comply with TIA Section 310(b). 
  
 Section 7.11 Preferential Collection of Claims Against Company. 
  
 The Trustee is subject to TIA Section 311(a), excluding any creditor
relationship listed in TIA Section 311(b). A Trustee who has resigned or been removed shall be subject to TIA Section 311(a) to the extent indicated. 
  
 ARTICLE 8 
  
 SATISFACTION AND DISCHARGE; DEFEASANCE 
  
 Section 8.1 Satisfaction and Discharge of Indenture. 
  
 This Indenture shall upon Company Order cease to be of further effect (except as hereinafter provided in this Section 8.1), and the Trustee, at the
expense of the Company, shall execute proper instruments acknowledging satisfaction and discharge of this Indenture, when 
  

 31. 

 (a) either 
  
 (i) all Securities theretofore authenticated and delivered (other than Securities that have been
destroyed, lost or stolen and that have been replaced or paid) have been delivered to the Trustee for cancellation; or 
  
 (ii) all such Securities not theretofore delivered to the Trustee for cancellation 
  
 (1) have become due and payable, or 
  
 (2) will become due and payable at their Stated
Maturity within one year, or 
  
 (3) are
to be called for redemption within one year under arrangements satisfactory to the Trustee for the giving of notice of redemption by the Trustee in the name, and at the expense, of the Company, or 
  
 (4) are deemed paid and discharged pursuant to
Section 8.3, as applicable; 
  
 and the Company, in the case of (1), (2) or (3)
above, has deposited or caused to be deposited with the Trustee as trust funds in trust an amount sufficient for the purpose of paying and discharging the entire indebtedness on such Securities not theretofore delivered to the Trustee for
cancellation, for principal and interest to the date of such deposit (in the case of Securities which have become due and payable on or prior to the date of such deposit) or to the Stated Maturity or redemption date, as the case may be; 

 
 (b) the Company has paid or caused to be paid all
other sums payable hereunder by the Company; and 
  
 (c) the Company has delivered to the Trustee an Officers’ Certificate and an Opinion of Counsel, each stating that all conditions precedent herein provided for relating to the satisfaction and discharge of this Indenture have
been complied with. 
  
 Notwithstanding the satisfaction and
discharge of this Indenture, the obligations of the Company to the Trustee under Section 7.7, and, if money shall have been deposited with the Trustee pursuant to clause (a) of this Section, the provisions of Sections 2.4, 2.7, 2.8, 8.1, 8.2 and 8.5
shall survive. 
  
 Section 8.2 Application of Trust Funds;
Indemnification. 
  
 (a) Subject to
the provisions of Section 8.5, all money deposited with the Trustee pursuant to Section 8.1, all money and U.S. Government Obligations or Foreign Government Obligations deposited with the Trustee pursuant to Section 8.3 or 8.4 and all money received
by the Trustee in respect of U.S. Government Obligations or Foreign Government Obligations deposited with the Trustee pursuant to Section 8.3 or 8.4, shall be held in trust and applied by it, in accordance with the provisions of the Securities and
this Indenture, to the 

  

 32. 

 
payment, either directly or through any Paying Agent (including the Company acting as its own Paying Agent) as the Trustee may determine, to the persons
entitled thereto, of the principal and interest for whose payment such money has been deposited with or received by the Trustee or to make mandatory sinking fund payments or analogous payments as contemplated by Sections 8.3 or 8.4. 
  
 (b) The Company shall pay and shall indemnify the
Trustee against any tax, fee or other charge imposed on or assessed against U.S. Government Obligations or Foreign Government Obligations deposited pursuant to Sections 8.3 or 8.4 or the interest and principal received in respect of such obligations
other than any payable by or on behalf of Holders. 
  
 (c) The Trustee shall deliver or pay to the Company from time to time upon Company Request any U.S. Government Obligations or Foreign Government Obligations or money held by it as provided in Sections 8.3 or 8.4 which are then in
excess of the amount thereof which then would have been required to be deposited for the purpose for which such U.S. Government Obligations or Foreign Government Obligations or money were deposited or received. This provision shall not authorize the
sale by the Trustee of any U.S. Government Obligations or Foreign Government Obligations held under this Indenture. 
  
 Section 8.3 Legal Defeasance of Securities of any Series. 
  

Unless this Section 8.3 is otherwise specified, pursuant to Section 2.2.21, to be inapplicable to Securities of any Series, the Company shall be deemed
to have paid and discharged the entire indebtedness on all the outstanding Securities of such Series on the 91st day after the date of the deposit referred to in subparagraph (d) hereof, and the provisions of this Indenture, as it relates to such
outstanding Securities of such Series, shall no longer be in effect (and the Trustee, at the expense of the Company, shall, at Company Request, execute proper instruments acknowledging the same), except as to: 
  
 (a) the rights of Holders of Securities of such
Series to receive, from the trust funds described in subparagraph (d) hereof, (i) payment of the principal of and each installment of principal of and interest on the outstanding Securities of such Series on the Stated Maturity of such principal or
installment of principal or interest and (ii) the benefit of any mandatory sinking fund payments applicable to the Securities of such Series on the day on which such payments are due and payable in accordance with the terms of this Indenture and the
Securities of such Series; 
  
 (b) the
provisions of Sections 2.4, 2.7, 2.8, 8.2, 8.3 and 8.5; and 
  
 (c) the rights, powers, trust and immunities of the Trustee hereunder; 
  
 provided that, the following conditions shall have been satisfied: 
  
 (d) the Company shall have deposited or caused to be deposited irrevocably with the Trustee as trust funds in trust for the purpose
of making the following payments, specifically pledged as security for and dedicated solely to the benefit of the Holders of such Securities (i) in the case of Securities of such Series denominated in Dollars, cash in 

  

 33. 

 
Dollars (or such other money or currencies as shall then be legal tender in the United States) and/or U.S. Government Obligations, or (ii) in the case of
Securities of such Series denominated in a Foreign Currency (other than a composite currency), money and/or Foreign Government Obligations, which through the payment of interest and principal in respect thereof, in accordance with their terms, will
provide (and without reinvestment and assuming no tax liability will be imposed on such Trustee), not later than one day before the due date of any payment of money, an amount in cash, sufficient, in the opinion of a nationally recognized firm of
independent public accountants expressed in a written certification thereof delivered to the Trustee, to pay and discharge each installment of principal (including mandatory sinking fund or analogous payments) of and interest, if any, on all the
Securities of such Series on the dates such installments of interest or principal are due; 
  
 (e) such deposit will not result in a breach or violation of, or constitute a default under, this Indenture or any other agreement
or instrument to which the Company is a party or by which it is bound; 
  
 (f) no Default or Event of Default with respect to the Securities of such Series shall have occurred and be continuing on the date of such deposit or during the period ending on the 91st day after such date;

  
 (g) the Company shall have delivered
to the Trustee an Officers’ Certificate and an Opinion of Counsel to the effect that (i) the Company has received from, or there has been published by, the Internal Revenue Service a ruling, or (ii) since the date of execution of this
Indenture, there has been a change in the applicable Federal income tax law, in either case to the effect that, and based thereon such Opinion of Counsel shall confirm that, the Holders of the Securities of such Series will not recognize income,
gain or loss for Federal income tax purposes as a result of such deposit, defeasance and discharge and will be subject to Federal income tax on the same amount and in the same manner and at the same times as would have been the case if such deposit,
defeasance and discharge had not occurred; 
  
 (h) the Company shall have delivered to the Trustee an Officers’ Certificate stating that the deposit was not made by the Company with the intent of preferring the Holders of the Securities of such Series over any other
creditors of the company or with the intent of defeating, hindering, delaying or defrauding any other creditors of the Company; 
  
 (i) such deposit shall not result in the trust arising from such deposit constituting an investment company (as defined in the
Investment Company Act of 1940, as amended), or such trust shall be qualified under such Act or exempt from regulation thereunder; and 
  
 (j) the Company shall have delivered to the Trustee an Officers’ Certificate and an Opinion of Counsel, each stating that all
conditions precedent provided for relating to the defeasance contemplated by this Section have been complied with. 
  
 Section 8.4 Covenant Defeasance. 
  
 Unless this Section 8.4 is otherwise specified pursuant to Section 2.2.21 to be inapplicable to Securities of any Series, on and after the 91st day after
the date of the deposit 

  

 34. 

 
referred to in subparagraph (a) hereof, the Company may omit to comply with any term, provision or condition set forth under Sections 4.2, 4.3, 4.4, 4.5,
4.6, and 5.1 as well as any additional covenants contained in a supplemental indenture hereto for a particular Series of Securities or a Board Resolution or an Officers’ Certificate delivered pursuant to Section 2.2.21 (and the failure to
comply with any such covenants shall not constitute a Default or Event of Default under Section 6.1) and the occurrence of any event described in clause (e) of Section 6.1 shall not constitute a Default or Event of Default hereunder, with respect to
the Securities of such Series, provided that the following conditions shall have been satisfied: 
  
 (a) With reference to this Section 8.4, the Company has deposited or caused to be irrevocably deposited (except as provided in
Section 8.2(c) ) with the Trustee as trust funds in trust, specifically pledged as security for, and dedicated solely to, the benefit of the Holders of such Securities (i) in the case of Securities of such Series denominated in Dollars, cash in
Dollars (or such other money or currencies as shall then be legal tender in the United States) and/or U.S. Government Obligations, or (ii) in the case of Securities of such Series denominated in a Foreign Currency (other than a composite currency),
money and/or Foreign Government Obligations, which through the payment of interest and principal in respect thereof, in accordance with their terms, will provide (and without reinvestment and assuming no tax liability will be imposed on such
Trustee), not later than one day before the due date of any payment of money, an amount in cash, sufficient, in the opinion of a nationally recognized firm of independent certified public accountants expressed in a written certification thereof
delivered to the Trustee, to pay principal and interest, if any, on and any mandatory sinking fund in respect of the Securities of such Series on the dates such installments of interest or principal are due; 
  
 (b) Such deposit will not result in a breach or
violation of, or constitute a default under, this Indenture or any other agreement or instrument to which the Company is a party or by which it is bound; 
  
 (c) No Default or Event of Default with respect to the Securities of such Series shall have occurred and be continuing on the date
of such deposit or during the period ending on the 91st day after such date; 
  
 (d) the Company shall have delivered to the Trustee an Opinion of Counsel confirming that Holders of the Securities of such Series will not recognize income, gain or loss for federal income tax purposes as a
result of such deposit and defeasance and will be subject to federal income tax on the same amounts, in the same manner and at the same times as would have been the case if such deposit and defeasance had not occurred; 
  
 (e) the Company shall have delivered to the Trustee
an Officers’ Certificate stating the deposit was not made by the Company with the intent of preferring the Holders of the Securities of such Series over any other creditors of the Company or with the intent of defeating, hindering, delaying or
defrauding any other creditors of the Company; and 
  

 35. 

 (f) The Company shall have delivered to the Trustee an Officers’ Certificate
and an Opinion of Counsel, each stating that all conditions precedent herein provided for relating to the defeasance contemplated by this Section have been complied with. 
  
 Section 8.5 Repayment to Company. 
  
 The Trustee and the Paying Agent shall pay to the Company upon request any money held by them for the payment of principal
and interest that remains unclaimed for two years or such other shorter period set forth in applicable escheat or abandoned or unclaimed property law. After that, Securityholders entitled to the money must look to the Company for payment as general
creditors unless an applicable abandoned property law designates another person. 
  
 Section 8.6 Reinstatement. 
  
 If the Trustee or Paying Agent is unable to apply any money or U.S. Government Obligations in accordance with Sections 8.1, 8.3 or 8.4, as the case may be, by reason of any legal proceeding or by reason of any order or judgment of any court
or governmental authority enjoining, restraining or otherwise prohibiting such application, the Company’s obligations under this Indenture and the Securities shall be revived and reinstated as though no deposit had occurred pursuant to Section
8.1, 8.3 or 8.4, as the case may be, until such time as the Trustee or Paying Agent is permitted to apply all such money or U.S. Government Obligations in accordance with Section 8.1, 8.3 or 8.4, as the case may be; provided, however, that if the
Company makes any payment of principal of, premium, if any, or interest on any Securities because of reinstatement of its obligations, the Company shall be subrogated to the rights of the holders of such Securities to receive such payment from the
money or U.S. Government Obligations held by the Trustee or Paying Agent. 
  
 ARTICLE 9 
  
 AMENDMENTS
AND WAIVERS 
  
 Section 9.1 Without Consent of Holders.

  
 The Company and the Trustee may amend or supplement this
Indenture or the Securities of one or more Series without the consent of any Securityholder: 
  
 (a) to cure any ambiguity, defect or inconsistency; 
  
 (b) to comply with Article V; 
  
 (c) to provide for uncertificated Securities in addition to or in place of certificated Securities;

  
 (d) to make any change that does not
adversely affect the rights of any Securityholder in any material respect; 
  
 (e) to provide for the issuance of and establish the form and terms and conditions of Securities of any Series as permitted by this Indenture; 
  

 36. 

 (f) to evidence and provide for the acceptance of appointment hereunder by a
successor Trustee with respect to the Securities of one or more Series and to add to or change any of the provisions of this Indenture as shall be necessary to provide for or facilitate the administration of the trusts hereunder by more than one
Trustee; or 
  
 (g) to comply with
requirements of the SEC in order to effect or maintain the qualification of this Indenture under the TIA. 
  
 Section 9.2 With Consent of Holders. 
  
 The Company and the Trustee may enter into a supplemental indenture with the written consent of the Holders of at least a majority in principal amount of
the outstanding Securities of each Series affected by such supplemental indenture (including consents obtained in connection with a tender offer or exchange offer for the Securities of such Series), for the purpose of adding any provisions to or
changing in any manner or eliminating any of the provisions of this Indenture or of any supplemental indenture or of modifying in any manner the rights of the Securityholders of each such Series. Except as provided in Section 6.13, the Holders of at
least a majority in principal amount of the outstanding Securities of each Series affected by such waiver by notice to the Trustee (including consents obtained in connection with a tender offer or exchange offer for the Securities of such Series)
may waive compliance by the Company with any provision of this Indenture or the Securities with respect to such Series. 
  
 It shall not be necessary for the consent of the Holders of Securities under this Section 9.2 to approve the particular form of any proposed supplemental
indenture or waiver, but it shall be sufficient if such consent approves the substance thereof. After a supplemental indenture or waiver under this Section becomes effective, the Company shall mail to the Holders of Securities affected thereby and,
if any Bearer Securities affected thereby are outstanding, publish on one occasion in an Authorized Newspaper, a notice briefly describing the supplemental indenture or waiver. Any failure by the Company to mail or publish such notice, or any defect
therein, shall not, however, in any way impair or affect the validity of any such supplemental indenture or waiver. 
  
 Section 9.3 Limitations. 
  
 Without the consent of each Securityholder affected, an amendment or waiver may not: 
  
 (a) change the amount of Securities whose Holders must consent to an amendment, supplement or waiver;

  
 (b) reduce the rate of or extend the
time for payment of interest (including default interest) on any Security; 
  
 (c) reduce the principal or change the Stated Maturity of any Security or reduce the amount of, or postpone the date fixed for, the payment of any sinking fund or analogous obligation; 
  
 (d) reduce the principal amount of Discount
Securities payable upon acceleration of the maturity thereof; 
  

 37. 

 (e) waive a Default or Event of Default in the payment of the principal of or
interest, if any, on any Security (except a rescission of acceleration of the Securities of any Series by the Holders of at least a majority in principal amount of the outstanding Securities of such Series and a waiver of the payment default that
resulted from such acceleration); 
  
 (f)
make the principal of or interest, if any, on any Security payable in any currency other than that stated in the Security; 
  
 (g) make any change in Sections 6.8, 6.13, 9.3, 10.15 or 10.16; or 
  
 (h) waive a redemption payment with respect to any Security or change any of the provisions with
respect to the redemption of any Securities. 
  
 Section 9.4
Compliance with Trust Indenture Act. 
  
 Every amendment to
this Indenture or the Securities of one or more Series shall be set forth in a supplemental indenture hereto that complies with the TIA as then in effect. 
  
 Section 9.5 Revocation and Effect of Consents. 
  
 Until an amendment or waiver becomes effective, a consent to it by a Holder of a Security is a continuing consent by the Holder and every subsequent
Holder of a Security or portion of a Security that evidences the same debt as the consenting Holder’s Security, even if notation of the consent is not made on any Security. However, any such Holder or subsequent Holder may revoke the consent as
to his Security or portion of a Security if the Trustee receives the notice of revocation before the date the amendment or waiver becomes effective. 
  
 Any amendment or waiver once effective shall bind every Securityholder of each Series affected by such amendment or waiver unless it is of the type
described in any of clauses (a) through (g) of Section 9.3. In that case, the amendment or waiver shall bind each Holder of a Security who has consented to it and every subsequent Holder of a Security or portion of a Security that evidences the same
debt as the consenting Holder’s Security. 
  
 Section 9.6
Notation on or Exchange of Securities. 
  
 The Trustee may
place an appropriate notation about an amendment or waiver on any Security of any Series thereafter authenticated. The Company in exchange for Securities of that Series may issue and the Trustee shall authenticate upon request new Securities of that
Series that reflect the amendment or waiver. 
  
 Section 9.7
Trustee Protected. 
  
 In executing, or accepting the
additional trusts created by, any supplemental indenture permitted by this Article or the modifications thereby of the trusts created by this Indenture, the Trustee shall be entitled to receive, and (subject to Section 7.1) shall be fully protected
in relying upon, an Opinion of Counsel stating that the execution of such supplemental indenture is 

  

 38. 

 
authorized or permitted by this Indenture. The Trustee shall sign all supplemental indentures, except that the Trustee need not sign any supplemental
indenture that adversely affects its rights. 
  
 ARTICLE 10

  
 MISCELLANEOUS 
  
 Section 10.1 Trust Indenture Act Controls. 
  
 If any provision of this Indenture limits, qualifies, or conflicts with
another provision which is required or deemed to be included in this Indenture by the TIA, such required or deemed provision shall control. 
  
 Section 10.2 Notices. 
  
 Any notice or communication by the Company or the Trustee to the other is duly given if in writing and delivered in person or mailed by first-class

  
 if to the Company: 
  
 Nuvelo, Inc. 
 675 Almanor Avenue 
 Sunnyvale, CA 94085

 Attention: General Counsel 
  
 if to the Trustee: 
  
 U.S. Bank National Association 
 60 Livingston
Avenue 
 St. Paul, MN 55107-2292 
 Attention: Ray Haverstock 
  
 The Company or the Trustee
by notice to the other may designate additional or different addresses for subsequent notices or communications. 
  
 Any notice or communication to a Securityholder shall be mailed by first-class mail to his address shown on the register kept by the Registrar and, if any
Bearer Securities are outstanding, published in an Authorized Newspaper. Failure to mail a notice or communication to a Securityholder of any Series or any defect in it shall not affect its sufficiency with respect to other Securityholders of that
or any other Series. 
  
 If a notice or communication is mailed or
published in the manner provided above, within the time prescribed, it is duly given, whether or not the Securityholder receives it. 
  
 If the Company mails a notice or communication to Securityholders, it shall mail a copy to the Trustee and each Agent at the same time. 
  

 39. 

 Section 10.3 Communication by Holders with Other Holders. 
  
 Securityholders of any Series may communicate pursuant to TIA Section 312(b)
with other Securityholders of that Series or any other Series with respect to their rights under this Indenture or the Securities of that Series or all Series. The Company, the Trustee, the Registrar and anyone else shall have the protection of TIA
Section 312(c). 
  
 Section 10.4 Certificate and Opinion as to
Conditions Precedent. 
  
 Upon any request or application by
the Company to the Trustee to take any action under this Indenture, the Company shall furnish to the Trustee: 
  
 (a) an Officers’ Certificate stating that, in the opinion of the signers, all conditions precedent, if any, provided for in
this Indenture relating to the proposed action have been complied with; and 
  
 (b) an Opinion of Counsel stating that, in the opinion of such counsel, all such conditions precedent have been complied with. 
  
 Section 10.5 Statements Required in Certificate or Opinion. 
  
 Each certificate or opinion with respect to compliance with a condition or
covenant provided for in this Indenture (other than a certificate provided pursuant to TIA Section 314(a) (4)) shall comply with the provisions of TIA Section 314(e) and shall include: 
  
 (a) a statement that the person making such certificate or opinion has read such covenant or
condition; 
  
 (b) a brief statement as to
the nature and scope of the examination or investigation upon which the statements or opinions contained in such certificate or opinion are based; 
  
 (c) a statement that, in the opinion of such person, he has made such examination or investigation as is necessary to enable him to
express an informed opinion as to whether or not such covenant or condition has been complied with; and 
  
 (d) a statement as to whether or not, in the opinion of such person, such condition or covenant has been complied with. 

 
 Section 10.6 Rules by Trustee and Agents. 
  
 The Trustee may make reasonable rules for action by or a meeting of
Securityholders of one or more Series. Any Agent may make reasonable rules and set reasonable requirements for its functions. 
  

 40. 

 Section 10.7 Legal Holidays. 
  
 Unless otherwise provided by Board Resolution, Officers’ Certificate or supplemental indenture for a particular Series,
a “Legal Holiday” is any day that is not a Business Day. If a payment date is a Legal Holiday at a place of payment, payment may be made at that place on the next succeeding day that is not a Legal Holiday, and no interest shall accrue for
the intervening period. 
  
 Section 10.8 No Recourse Against
Others. 
  
 A director, officer, employee or stockholder, as
such, of the Company shall not have any liability for any obligations of the Company under the Securities or the Indenture or for any claim based on, in respect of or by reason of such obligations or their creation. Each Securityholder by accepting
a Security waives and releases all such liability. The waiver and release are part of the consideration for the issue of the Securities. 
  
 Section 10.9 Counterparts. 
  
 This Indenture may be executed in any number of counterparts and by the parties hereto in separate counterparts, each of which when so executed shall be
deemed to be an original and all of which taken together shall constitute one and the same agreement. 
  
 Section 10.10 Governing Laws. 
  
 THIS INDENTURE AND THE SECURITIES SHALL BE GOVERNED BY THE LAWS OF THE STATE OF NEW YORK APPLICABLE TO AGREEMENTS MADE AND TO BE PERFORMED IN SUCH STATE,
WITHOUT REGARD TO THE CONFLICT OF LAWS PROVISIONS THEREOF. 
  
 Section 10.11 No Adverse Interpretation of Other Agreements. 
  
 This Indenture may not be used to interpret another indenture, loan or debt agreement of the Company or a Subsidiary. Any such indenture, loan or debt agreement may not be used to interpret this Indenture. 

 
 Section 10.12 Successors. 
  
 All agreements of the Company in this Indenture and the Securities shall
bind its successor. All agreements of the Trustee in this Indenture shall bind its successor. 
  
 Section 10.13 Severability. 
  
 In case any provision in this Indenture or in the Securities shall be invalid, illegal or unenforceable, the validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby. 

 

 41. 

 Section 10.14 Table of Contents, Headings, Etc. 
  
 The Table of Contents, Cross Reference Table, and headings of the Articles
and Sections of this Indenture have been inserted for convenience of reference only, are not to be considered a part hereof, and shall in no way modify or restrict any of the terms or provisions hereof. 
  
 Section 10.15 Securities in a Foreign Currency or in ECU. 

 
 Unless otherwise specified in a Board Resolution, a supplemental
indenture hereto or an Officers’ Certificate delivered pursuant to Section 2.2 of this Indenture with respect to a particular Series of Securities, whenever for purposes of this Indenture any action may be taken by the Holders of a specified
percentage in aggregate principal amount of Securities of all Series or all Series affected by a particular action at the time outstanding and, at such time, there are outstanding Securities of any Series which are denominated in a coin or currency
other than Dollars (including ECUs), then the principal amount of Securities of such Series which shall be deemed to be outstanding for the purpose of taking such action shall be that amount of Dollars that could be obtained for such amount at the
Market Exchange Rate at such time. For purposes of this Section 10.15, “Market Exchange Rate” shall mean the noon Dollar buying rate in New York City for cable transfers of that currency as published by the Federal Reserve Bank of New
York; provided, however, in the case of ECUs, Market Exchange Rate shall mean the rate of exchange determined by the Commission of the European Union (or any successor thereto) as published in the Official Journal of the European Union (such
publication or any successor publication, the “Journal”). If such Market Exchange Rate is not available for any reason with respect to such currency, the Trustee shall use, in its sole discretion and without liability on its part, such
quotation of the Federal Reserve Bank of New York or, in the case of ECUs, the rate of exchange as published in the Journal, as of the most recent available date, or quotations or, in the case of ECUs, rates of exchange from one or more major banks
in The City of New York or in the country of issue of the currency in question or, in the case of ECUs, in Luxembourg or such other quotations or, in the case of ECUs, rates of exchange as the Trustee, upon consultation with the Company, shall deem
appropriate. The provisions of this paragraph shall apply in determining the equivalent principal amount in respect of Securities of a Series denominated in currency other than Dollars in connection with any action taken by Holders of Securities
pursuant to the terms of this Indenture. 
  
 All decisions and
determinations of the Trustee regarding the Market Exchange Rate or any alternative determination provided for in the preceding paragraph shall be in its sole discretion and shall, in the absence of manifest error, be conclusive to the extent
permitted by law for all purposes and irrevocably binding upon the Company and all Holders. 
  
 Section 10.16 Judgment Currency. 
  
 The Company agrees, to the fullest extent that it may effectively do so under applicable law, that (a) if for the purpose of obtaining judgment in any court it is necessary to convert the sum due in respect of the
principal of or interest or other amount on the Securities of any Series (the “Required Currency”) into a currency in which a judgment will be rendered (the “Judgment Currency”), the rate of exchange used shall be the rate at
which in accordance with normal banking procedures the Trustee could purchase in The City of New York the Required Currency 

  

 42. 

 
with the Judgment Currency on the day on which final unappealable judgment is entered, unless such day is not a New York Banking Day, then, the rate of
exchange used shall be the rate at which in accordance with normal banking procedures the Trustee could purchase in The City of New York the Required Currency with the Judgment Currency on the New York Banking Day preceding the day on which final
unappealable judgment is entered and (b) its obligations under this Indenture to make payments in the Required Currency (i) shall not be discharged or satisfied by any tender, any recovery pursuant to any judgment (whether or not entered in
accordance with clause (a) ), in any currency other than the Required Currency, except to the extent that such tender or recovery shall result in the actual receipt, by the payee, of the full amount of the Required Currency expressed to be payable
in respect of such payments, (ii) shall be enforceable as an alternative or additional cause of action for the purpose of recovering in the Required Currency the amount, if any, by which such actual receipt shall fall short of the full amount of the
Required Currency so expressed to be payable, and (iii) shall not be affected by judgment being obtained for any other sum due under this Indenture. For purposes of the foregoing, “New York Banking Day” means any day except a Saturday,
Sunday or a legal holiday in The City of New York on which banking institutions are authorized or required by law, regulation or executive order to close. 
  
 ARTICLE 11 
  
 SINKING FUNDS 
  
 Section 11.1 Applicability of Article. 
  
 The provisions of this Article shall be applicable to any sinking fund for the retirement of the Securities of a Series, except as otherwise permitted or required by any form of Security of such Series issued pursuant
to this Indenture. 
  
 The minimum amount of any sinking fund
payment provided for by the terms of the Securities of any Series is herein referred to as a “mandatory sinking fund payment” and any other amount provided for by the terms of Securities of such Series is herein referred to as an
“optional sinking fund payment.” If provided for by the terms of Securities of any Series, the cash amount of any sinking fund payment may be subject to reduction as provided in Section 11.2. Each sinking fund payment shall be applied to
the redemption of Securities of any Series as provided for by the terms of the Securities of such Series. 
  
 Section 11.2 Satisfaction of Sinking Fund Payments with Securities. 
  
 The Company may, in satisfaction of all or any part of any sinking fund payment with respect to the Securities of any Series
to be made pursuant to the terms of such Securities (1) deliver outstanding Securities of such Series to which such sinking fund payment is applicable (other than any of such Securities previously called for mandatory sinking fund redemption) and
(2) apply as credit Securities of such Series to which such sinking fund payment is applicable and which have been redeemed either at the election of the Company pursuant to the terms of such Series of Securities (except pursuant to any mandatory
sinking fund) or through the application of permitted optional sinking fund payments or other optional redemptions pursuant to the terms of such Securities, provided that such Securities have not been previously so 

  

 43. 

 
credited. Such Securities shall be received by the Trustee, together with an Officers’ Certificate with respect thereto, not later than 15 days prior to
the date on which the Trustee begins the process of selecting Securities for redemption, and shall be credited for such purpose by the Trustee at the price specified in such Securities for redemption through operation of the sinking fund and the
amount of such sinking fund payment shall be reduced accordingly. If as a result of the delivery or credit of Securities in lieu of cash payments pursuant to this Section 11.2, the principal amount of Securities of such Series to be redeemed in
order to exhaust the aforesaid cash payment shall be less than $100,000, the Trustee need not call Securities of such Series for redemption, except upon receipt of a Company Order that such action be taken, and such cash payment shall be held by the
Trustee or a Paying Agent and applied to the next succeeding sinking fund payment, provided, however, that the Trustee or such Paying Agent shall from time to time upon receipt of a Company Order pay over and deliver to the Company any cash payment
so being held by the Trustee or such Paying Agent upon delivery by the Company to the Trustee of Securities of that Series purchased by the Company having an unpaid principal amount equal to the cash payment required to be released to the Company.

  
 Section 11.3 Redemption of Securities for Sinking Fund.

  
 Not less than 45 days (unless otherwise indicated in the
Board Resolution, supplemental indenture hereto or Officers’ Certificate in respect of a particular Series of Securities) prior to each sinking fund payment date for any Series of Securities, the Company will deliver to the Trustee an
Officers’ Certificate specifying the amount of the next ensuing mandatory sinking fund payment for that Series pursuant to the terms of that Series, the portion thereof, if any, which is to be satisfied by payment of cash and the portion
thereof, if any, which is to be satisfied by delivering and crediting of Securities of that Series pursuant to Section 11.2, and the optional amount, if any, to be added in cash to the next ensuing mandatory sinking fund payment, and the Company
shall thereupon be obligated to pay the amount therein specified. Not less than 30 days (unless otherwise indicated in the Board Resolution, Officers’ Certificate or supplemental indenture in respect of a particular Series of Securities) before
each such sinking fund payment date the Trustee shall select the Securities to be redeemed upon such sinking fund payment date in the manner specified in Section 3.2 and cause notice of the redemption thereof to be given in the name of and at the
expense of the Company in the manner provided in Section 3.3. Such notice having been duly given, the redemption of such Securities shall be made upon the terms and in the manner stated in Sections 3.4, 3.5 and 3.6. 
  
 ARTICLE 12 
  
 SUBORDINATION OF SECURITIES 
  
 Section 12.1 Agreement of Subordination. 
  
 The Company covenants and agrees, and each Holder of Securities issued
hereunder by his acceptance thereof likewise covenants and agrees, that all Securities shall be issued subject to the provisions of this Article XII; and each Person holding any Security, whether upon original issue or upon transfer, assignment or
exchange thereof, accepts and agrees to be bound by such provisions. 
  

 44. 

 The payment of the principal of, premium, if any, and interest on all Securities (including, but not
limited to, the redemption price with respect to the Securities called for redemption in accordance with Article 3 as provided in the Indenture) issued hereunder shall, to the extent and in the manner hereinafter set forth, be subordinated and
subject in right of payment to the prior payment in full of all Senior Indebtedness, whether outstanding at the date of this Indenture or thereafter incurred. 
  

No provision of this Article XII shall prevent the occurrence of any default or Event of Default hereunder. 
  
 Section 12.2 Payments to Holders. 
  
 No payment shall be made with respect to the principal of, or premium, if
any, or interest on the Securities (including, but not limited to, the redemption price with respect to the Securities to be called for redemption in accordance with Article III as provided in the Indenture), except payments and distributions made
by the Trustee as permitted by the first or second paragraph of Section 12.5, if: 
  
 (i) a default in the payment of principal, premium, interest, rent or other obligations due on any Senior Indebtedness occurs and
is continuing (or, in the case of Senior Indebtedness for which there is a period of grace, in the event of such a default that continues beyond the period of grace, if any, specified in the instrument or lease evidencing such Senior Indebtedness),
unless and until such default shall have been cured or waived or shall have ceased to exist; or 
  
 (ii) a default, other than a payment default, on a Designated Senior Indebtedness occurs and is continuing that then permits
holders of such Designated Senior Indebtedness to accelerate its maturity and the Trustee receives a notice of the default (a “Payment Blockage Notice”) from a Representative or the Company. 
  
 If the Trustee receives any Payment Blockage Notice pursuant to clause (ii)
above, no subsequent Payment Blockage Notice shall be effective for purposes of this Section unless and until (a) at least 365 days shall have elapsed since the initial effectiveness of the immediately prior Payment Blockage Notice, and (b) all
scheduled payments of principal, premium, if any, and interest on the Securities that have come due have been paid in full in cash. No nonpayment default that existed or was continuing on the date of delivery of any Payment Blockage Notice to the
Trustee shall be, or be made, the basis for a subsequent Payment Blockage Notice. 
  
 The Company may and shall resume payments on and distributions in respect of the Securities upon the earlier of: 
  
 (1) the date upon which the default is cured or waived or ceases to exist, or 
  
 (2) in the case of a default referred to in clause
(ii) above, 179 days pass after notice is received if the maturity of such Designated Senior Indebtedness has not been accelerated, unless this Article XII otherwise prohibits the payment or distribution at the time of such payment or distribution.

  

 45. 

 Upon any payment by the Company, or distribution of assets of the Company of any kind or character,
whether in cash, property or securities, to creditors upon any dissolution or winding-up or liquidation or reorganization of the Company, whether voluntary or involuntary or in bankruptcy, insolvency, receivership or other proceedings, all amounts
due or to become due upon all Senior Indebtedness shall first be paid in full in cash or other payment satisfactory to the holders of such Senior Indebtedness, or payment thereof in accordance with its terms provided for in cash or other payment
satisfactory to the holders of such Senior Indebtedness, before any payment is made on account of the principal of, premium, if any, or interest on the Securities (except payments made pursuant to Article VI from monies deposited with the Trustee
pursuant thereto prior to commencement of proceedings for such dissolution, winding-up, liquidation or reorganization); and upon any such dissolution or winding-up or liquidation or reorganization of the Company or bankruptcy, insolvency,
receivership or other proceeding, any payment by the Company, or distribution of assets of the Company of any kind or character, whether in cash, property or securities, to which the Holders of the Securities or the Trustee would be entitled, except
for the provision of this Article XII, shall (except as aforesaid) be paid by the Company or by any receiver, trustee in bankruptcy, liquidating trustee, agent or other Person making such payment or distribution, or by the Holders of the Securities
or by the Trustee under this Indenture if received by them or it, directly to the holders of Senior Indebtedness (pro rata to such holders on the basis of the respective amounts of Senior Indebtedness held by such holders, or as otherwise required
by law or a court order) or their representative or representatives, or to the trustee or trustees under any indenture pursuant to which any instruments evidencing any Senior Indebtedness may have been issued, as their respective interests may
appear, to the extent necessary to pay all Senior Indebtedness in full, in cash or other payment satisfactory to the holders of such Senior Indebtedness, after giving effect to any concurrent payment or distribution to or for the holders of Senior
Indebtedness, before any payment or distribution or provision therefor is made to the Holders of the Securities or to the Trustee. 
  
 For purposes of this Article XII, the words, “cash, property or securities” shall not be deemed to include shares of stock of the Company as
reorganized or readjusted, or securities of the Company or any other corporation provided for by a plan of reorganization or readjustment, the payment of which is subordinated at least to the extent provided in this Article XII with respect to the
Securities to the payment of all Senior Indebtedness which may at the time be outstanding; provided that (i) the Senior Indebtedness is assumed by the new corporation, if any, resulting from any reorganization or readjustment, and (ii) the rights of
the holders of Senior Indebtedness (other than leases which are not assumed by the Company or the new corporation, as the case may be) are not, without the consent of such holders, altered by such reorganization or readjustment. The consolidation of
the Company with, or the merger of the Company into, another corporation or the liquidation or dissolution of the Company following the conveyance or transfer of its property as an entirety, or substantially as an entirety, to another corporation
upon the terms and conditions provided for in Article V shall not be deemed a dissolution, winding-up, liquidation or reorganization for the purposes of this Section 12.2 if such other corporation shall, as a part of such consolidation, merger,
conveyance or transfer, comply with the conditions stated in Article V. 
  
 In the event of the acceleration of the Securities because of an Event of Default, no payment or distribution shall be made to the Trustee or any Holder of Securities in respect of the principal of, premium, if any, or interest on the
Securities (including, but not limited to, the 

  

 46. 

 
redemption price with respect to the Securities called for redemption in accordance with Article 3 as provided in the Indenture), except payments and
distributions made by the Trustee as permitted by the first or second paragraph of Section 12.5, until all Senior Indebtedness has been paid in full in cash or other payment satisfactory to the holders of Senior Indebtedness or such acceleration is
rescinded in accordance with the terms of this Indenture. If payment of the Securities is accelerated because of an Event of Default, the Company shall promptly notify holders of Senior Indebtedness of the acceleration at the address set forth in
the notice from the Agent (or successor agent) to the Trustee as being the address to which the Trustee should send its notice pursuant to this Section 12.2, unless there are no payment obligations of the Company thereunder and all obligations
thereunder to extend credit have been terminated or expired. 
  
 In the event that, notwithstanding the foregoing provisions, any payment or distribution of assets of the Company of any kind or character, whether in cash, property or securities (including, without limitation, by way of setoff or
otherwise), prohibited by the foregoing, shall be received by the Trustee or the Holders of the Securities before all Senior Indebtedness is paid in full in cash or other payment satisfactory to the holders of such Senior Indebtedness, or provision
is made for such payment thereof in accordance with its terms in cash or other payment satisfactory to the holders of such Senior Indebtedness, such payment or distribution shall be held in trust for the benefit of and shall be paid over or
delivered to the holders of Senior Indebtedness or their representative or representatives, or to the trustee or trustees under any indenture pursuant to which any instruments evidencing any Senior Indebtedness may have been issued, as their
respective interests may appear, as calculated by the Company, for application to the payment of all Senior Indebtedness remaining unpaid to the extent necessary to pay all Senior Indebtedness in full in cash or other payment satisfactory to the
holders of such Senior Indebtedness, after giving effect to any concurrent payment or distribution to or for the holders of such Senior Indebtedness. 
  
 Nothing in this Section 12.2 shall apply to claims of, or payments to, the Trustee under or pursuant to Section 7.7. This Section 12.2 shall be subject to
the further provisions of Section 12.5. 
  
 Section 12.3
Subrogation of Securities. 
  
 Subject to the payment in full
of all Senior Indebtedness, the rights of the Holders of the Securities shall be subrogated to the extent of the payments or distributions made to the holders of such Senior Indebtedness pursuant to the provisions of this Article XII (equally and
ratably with the holders of all indebtedness of the Company which by its express terms is subordinated to other indebtedness of the Company to substantially the same extent as the Securities are subordinated and is entitled to like rights of
subrogation) to the rights of the holders of Senior Indebtedness to receive payments or distributions of cash, property or securities of the Company applicable to the Senior Indebtedness until the principal, premium, if any, and interest on the
Securities shall be paid in full; and, for the purposes of such subrogation, no payments or distributions to the holders of the Senior Indebtedness of any cash, property or securities to which the Holders of the Securities or the Trustee would be
entitled except for the provisions of this Article XII, and no payment over pursuant to the provisions of this Article XII, to or for the benefit of the holders of Senior Indebtedness by Holders of the Securities or the Trustee, shall, as between
the Company, its creditors other than holders of Senior Indebtedness, and the Holders of 

  

 47. 

 
the Securities, be deemed to be a payment by the Company to or on account of the Senior Indebtedness; and no payments or distributions of cash, property or
securities to or for the benefit of the Holders of the Securities pursuant to the subrogation provisions of this Article XII, which would otherwise have been paid to the holders of Senior Indebtedness shall be deemed to be a payment by the Company
to or for the account of the Securities. It is understood that the provisions of this Article XII are and are intended solely for the purposes of defining the relative rights of the Holders of the Securities, on the one hand, and the holders of the
Senior Indebtedness, on the other hand. 
  
 Nothing contained in
this Article XII or elsewhere in this Indenture or in the Securities is intended to or shall impair, as among the Company, its creditors other than the holders of Senior Indebtedness, and the Holders of the Securities, the obligation of the Company,
which is absolute and unconditional, to pay to the Holders of the Securities the principal of (and premium, if any) and interest on the Securities as and when the same shall become due and payable in accordance with their terms, or is intended to or
shall affect the relative rights of the Holders of the Securities and creditors of the Company other than the holders of the Senior Indebtedness, nor shall anything herein or therein prevent the Trustee or the Holder of any Security from exercising
all remedies otherwise permitted by applicable law upon default under this Indenture, subject to the rights, if any, under this Article XII of the holders of Senior Indebtedness in respect of cash, property or securities of the Company received upon
the exercise of any such remedy. 
  
 Upon any payment or
distribution of assets of the Company referred to in this Article XII, the Trustee, subject to the provisions of Section 7.1, and the Holders of the Securities shall be entitled to rely upon any order or decree made by any court of competent
jurisdiction in which such bankruptcy, dissolution, winding-up, liquidation or reorganization proceedings are pending, or a certificate of the receiver, trustee in bankruptcy, liquidating trustee, agent or other person making such payment or
distribution, delivered to the Trustee or to the Holders of the Securities, for the purpose of ascertaining the persons entitled to participate in such distribution, the holders of the Senior Indebtedness and other indebtedness of the Company, the
amount thereof or payable thereon and all other facts pertinent thereto or to this Article XII. 
  
 Section 12.4 Authorization to Effect Subordination. 
  
 Each Holder of a Security by the holder’s acceptance thereof authorizes and directs the Trustee on the holder’s behalf to take such action as
may be necessary or appropriate to effectuate the subordination as provided in this Article XII and appoints the Trustee to act as the holder’s attorney-in-fact for any and all such purposes. If the Trustee does not file a proper proof of claim
or proof of debt in the form required in any proceeding referred to in Section 6.3 hereof at least 30 days before the expiration of the time to file such claim, the holders of any Senior Indebtedness or their representatives are hereby authorized to
file an appropriate claim for and on behalf of the Holders of the Securities. 
  
 Section 12.5 Notice to Trustee. 
  
 The Company shall give prompt written notice in the form of an Officers’ Certificate to a Responsible Officer of the Trustee and to any paying agent of any fact known to the Company which would prohibit the making of any payment of
monies to or by the Trustee or any paying 

  

 48. 

 
agent in respect of the Securities pursuant to the provisions of this Article XII. Notwithstanding the provisions of this Article XII or any other provision
of this Indenture, the Trustee shall not be charged with knowledge of the existence of any facts which would prohibit the making of any payment of monies to or by the Trustee in respect of the Securities pursuant to the provisions of this Article
XII, unless and until a Responsible Officer of the Trustee shall have received written notice thereof at the Corporate Trust Office from the Company (in the form of an Officers’ Certificate) or a Representative or a holder or holders of Senior
Indebtedness or from any trustee thereof; and before the receipt of any such written notice, the Trustee, subject to the provisions of Section 7.1, shall be entitled in all respects to assume that no such facts exist; provided that if on a date not
fewer than two Business Days prior to the date upon which by the terms hereof any such monies may become payable for any purpose (including, without limitation, the payment of the principal of, or premium, if any, or interest on any Security) the
Trustee shall not have received, with respect to such monies, the notice provided for in this Section 12.5, then, anything herein contained to the contrary notwithstanding, the Trustee shall have full power and authority to receive such monies and
to apply the same to the purpose for which they were received, and shall not be affected by any notice to the contrary which may be received by it on or after such prior date. 
  
 Notwithstanding anything in this Article XII to the contrary, nothing shall prevent any payment by the Trustee to the
Holders of monies deposited with it pursuant to Section 8.1, and any such payment shall not be subject to the provisions of Section 12.1 or 12.2. 
  
 The Trustee, subject to the provisions of Section 7.1, shall be entitled to rely on the delivery to it of a written notice by a Representative or a person
representing himself to be a holder of Senior Indebtedness (or a trustee on behalf of such holder) to establish that such notice has been given by a Representative or a holder of Senior Indebtedness or a trustee on behalf of any such holder or
holders. In the event that the Trustee determines in good faith that further evidence is required with respect to the right of any person as a holder of Senior Indebtedness to participate in any payment or distribution pursuant to this Article XII,
the Trustee may request such person to furnish evidence to the reasonable satisfaction of the Trustee as to the amount of Senior Indebtedness held by such person, the extent to which such person is entitled to participate in such payment or
distribution and any other facts pertinent to the rights of such person under this Article XII, and if such evidence is not furnished the Trustee may defer any payment to such person pending judicial determination as to the right of such person to
receive such payment. 
  
 Section 12.6 Trustee’s Relation
to Senior Indebtedness. 
  
 The Trustee in its individual
capacity shall be entitled to all the rights set forth in this Article XII in respect of any Senior Indebtedness at any time held by it, to the same extent as any other holder of Senior Indebtedness, and nothing in Section 7.11 or elsewhere in this
Indenture shall deprive the Trustee of any of its rights as such holder. 
  
 With respect to the holders of Senior Indebtedness, the Trustee undertakes to perform or to observe only such of its covenants and obligations as are specifically set forth in this Article XII, and no implied
covenants or obligations with respect to the holders of Senior Indebtedness shall be read into this Indenture against the Trustee. The Trustee shall not be deemed to owe any 

  

 49. 

 
fiduciary duty to the holders of Senior Indebtedness and, subject to the provisions of Section 7.1, the Trustee shall not be liable to any holder of Senior
Indebtedness if it shall pay over or deliver to Holders of Securities, the Company or any other person money or assets to which any holder of Senior Indebtedness shall be entitled by virtue of this Article XII or otherwise. 
  
 Section 12.7 No Impairment of Subordination. 
  
 No right of any present or future holder of any Senior Indebtedness to
enforce subordination as herein provided shall at any time in any way be prejudiced or impaired by any act or failure to act on the part of the Company or by any act or failure to act, in good faith, by any such holder, or by any noncompliance by
the Company with the terms, provisions and covenants of this Indenture, regardless of any knowledge thereof which any such holder may have or otherwise be charged with. 
  
 Section 12.8 Article Applicable to Paying Agents. 
  
 If at any time any Paying Agent other than the Trustee shall have been appointed by the Company and be then acting
hereunder, the term “Trustee” as used in this Article shall (unless the context otherwise requires) be construed as extending to and including such Paying Agent within its meaning as fully for all intents and purposes as if such Paying
Agent were named in this Article in addition to or in place of the Trustee; provided, however, that the first paragraph of Section 12.5 shall not apply to the Company or any Affiliate of the Company if it or such Affiliate acts as Paying Agent.

  
 Section 12.9 Senior Indebtedness Entitled to Rely.

  
 The holders of Senior Indebtedness (including, without
limitation, Designated Senior Indebtedness) shall have the right to rely upon this Article XII, and no amendment or modification of the provisions contained herein shall diminish the rights of such holders unless such holders shall have agreed in
writing thereto. 
  

 50. 

 IN WITNESS WHEREOF, the parties hereto have caused this Indenture to be duly executed as of the day and
year first above written. 
  

			
	 NUVELO, INC.

		
	 By: 
	 	 
	 	 	 Name:

	 	 	 Its:

	
	 U.S. BANK NATIONAL ASSOCIATION

		
	 By: 
	 	 
	 	 	 Name:

	 	 	 Its:

  

 51.Employment Agreement

 Exhibit 10.18 
  
 EMPLOYMENT AGREEMENT 
  
 THIS EMPLOYMENT AGREEMENT (the “Agreement”) is made and entered into as of the 30th day of September, 2004, by and between Bob
O’Leary Health Food Distributor Co., Inc., a Pennsylvania corporation, (together with its successors and assigns, the “Company”), and Joseph Mies (the “Officer”). 
  
 In consideration of the mutual promises, agreements and covenants set forth
herein and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto hereby agree as follows: 
  

1. Employment Period. Subject to Section 3, the Company hereby agrees to employ the Officer, and the Officer hereby agrees to be employed by the
Company, in accordance with the terms and provisions of this Agreement, for an initial term beginning on October 1, 2004, and expiring on September 30, 2007 (the “Initial Term”). After the expiration of the Initial Term, the term of
your employment shall automatically be extended without further action by the parties for successive one (1) year renewal terms, provided that if either party gives the other party at least thirty (30) days advance written notice of his or its
intention to not renew this Agreement for an additional term, the Agreement shall terminate upon the expiration of the then current term (the Initial Term and any subsequent renewal term shall be defined as the “Employment Period”).

  
 2. Terms of Employment. 
  
 (a) Position and Duties. 
  
 (i) During the Employment Period, the Officer shall serve as
Chief Operating Officer of the Company and, in so doing, the Officer shall report to the Chief Executive Officer of the Company. The Officer shall have supervision and control over, and responsibility for, the day-to-day operations of the Company
and shall have such other powers and duties as may from time to time be prescribed by the Chief Executive Officer, so long as such powers and duties are reasonable and customary for the Chief Operating Officer of an enterprise comparable to the
Company. 
  
 (ii) During the Employment Period,
but excluding any periods of vacation and sick leave to which the Officer is entitled, the Officer shall devote all of his business time to the business and affairs of the Company and shall use the Officer’s best efforts to perform faithfully,
effectively and efficiently his responsibilities to the Company. 
  
 (iii) During the Employment Period, the Officer (A) shall inform the Company of each business opportunity which falls within or is related to the business plan of the Company of which he becomes aware and shall not,
directly or indirectly, exploit any such opportunity for his own account and (B) shall not render any services to any other such person or business. 
  

 (b) Compensation. 
  
 (i) Base Salary. During the Employment Period, the Officer shall receive an annual base salary
(“Annual Base Salary”), pro rated for any partial year, which shall be paid in accordance with the customary payroll practices of the Company, of One Hundred Thousand and 00/100 Dollars ($100,000.00). By referring to an “Annual
Base Salary,” the Company is not modifying its termination rights under Section 3 of this Agreement. 
  
 (ii) Bonus Pay. The Officer shall be entitled to receive a bonus from the Company for 2004 in an amount equal to the amount of
accrued bonus liability allocated to the Officer on the Company’s balance sheet dated the date of this Agreement and, to the extent this amount only reflects a partial year bonus, the Company shall pay an additional amount for the remainder of
the year which amount shall be calculated consistent with and in the same manner as the calculation of the partial year bonus. 
  
 A. Net Income. Commencing on January 1, 2005, and continuing during the Employment Period, the Officer shall be entitled to
receive three percent (3%) of the incremental increase in Net Income for each Period as compared to the prior Period (the “Change in Net Income”). Also, the Officer shall, at his discretion, be entitled to allocate up to an
additional two percent (2%) of the Change in Net Income among the other employees of the Company. “Net Income” shall mean total revenues minus total expenses of the Company. “Period” shall mean each calendar year of
the Company during the Employment Period, or portion of such year if the Agreement terminates or expires during the year. 
  
 B. Gross Profit. Commencing on January 1, 2005, and continuing during the Employment Period, the Officer shall be entitled to
receive five percent (5%) of the Gross Profit of the Company for each Period (the “Gross Profit Bonus”) that is derived solely from the sale of the Company’s proprietary and branded products which are newly developed and first
sold after the date of this Agreement. “Gross Profit” shall mean the revenues of the Company derived from the sale of the Company’s proprietary and branded products less (i) cost of goods sold, (ii) commission expense, (iii)
the cost associated with returned or undeliverable products, and (iv) other expenses directly related to the creation of the products being sold. 
  
 C. Procedure. On or before sixty (60) days following the end of each Period, the Company shall (1) determine the Change in the Net
Income for the Period, (2) calculate the Gross Profit Bonus for the Period, and (3) deliver a written statement (the “Bonus Statement”) detailing the calculation of the Change in Net Income and the Gross Profit Bonus to the Officer.
The calculation of the Change in Net Income and the Gross Profit Bonus shall be prepared in the sole discretion of the Company from the books and records of the Company and in accordance with generally accepted accounting principles. 
  
 (iii) Benefits. During the Employment Period, the
Officer shall, subject to meeting the terms, conditions and eligibility requirements, including any amendments or modifications thereto, be entitled to receive all of the fringe benefits and participate in all of the health, savings and retirement
plans and programs that are available to the Company’s employees. 
  

 2 

 (iv) Expenses. During the Employment Period, the Officer shall be entitled to
receive prompt reimbursement for all reasonable business expenses incurred by the Officer in accordance with the policies, practices and procedures of the Company as are in effect from time to time. 
  
 (v) Vacation and Holidays. During the Employment
Period, the Officer shall be entitled to three (3) weeks paid vacation per year, and paid holidays, sick and personal days in accordance with the policies of the Company as are in effect, from time to time, for its officers. 
  
 (vi) Key Man Life Insurance. The Company shall obtain
a One Million Dollar ($1,000,000) term life insurance policy on the life of the Officer and pay all premiums due under such policy during the Employment Period, the proceeds of which shall be payable to the Company. 
  
 (c) Representations. The Company hereby represents
and warrants to the Officer that it has the legal capacity to execute and perform this Agreement, that this Agreement is a valid and binding agreement enforceable against the Company according to its terms and that the execution and performance of
this Agreement by the Company does not violate the terms of any existing agreement or understanding, written or oral, to which the Company is a party or any judgment or decree to which the Company is subject. The Officer hereby represents and
warrants to the Company that he has the legal capacity to execute and perform this Agreement, that this Agreement is a valid and binding agreement enforceable against him according to its terms and that the execution and performance of this
Agreement by him does not violate the terms of any existing agreement or understanding, written or oral, to which the Officer is a party or any judgment or decree to which the Officer is subject. In addition, the Officer represents and warrants to
the Company that, to his knowledge, he has no physical or mental condition (that could prevent him, or make it more difficult for him, to perform his obligations under this Agreement during the Employment Period. 
  
 3. Termination of Employment. 
  
 (a) Death or Disability. The Officer’s
employment shall terminate automatically upon the Officer’s death during the Employment Period. If a Disability of the Officer occurs during the Employment Period, the Company may give to the Officer written notice in accordance with Section
12(b) of its intention to terminate the Officer’s employment. In such event, the Officer’s employment with the Company shall terminate effective on the 30th day after the giving of such notice (the “Disability Effective
Date”). For purposes of this Agreement, “Disability” shall mean the Officer’s inability to perform his duties and obligations hereunder (with reasonable accommodation only if required by applicable law) for more than
ninety (90) days in any 180-day period due to mental or physical incapacity as determined by a physician selected by the Company or its insurers. 
  
 (b) (i) Cause. The Company may terminate the Officer’s employment during the Employment Period for Cause or without Cause. For
purposes of this Agreement, “Cause” shall mean (i) a breach by the Officer of the Officer’s obligations under Section 2(a) (other than as a result of physical or mental incapacity) or any other material terms or
conditions 

  

 3 

 
of this Agreement which constitutes a material nonperformance by the Officer of his obligations and duties under this Agreement that is not cured within ten
(10) business days after the Company’s provision to the Officer of written notice describing the alleged breach; (ii) commission by the Officer of an act of fraud upon, or willful misconduct toward the Company; (iii) a breach by the Officer of
any of Sections 6 through 9 hereof; (iv) the Officer’s conviction of or no contest plea to a felony or crime involving moral turpitude; (v) any judicial or arbitrators’ determination that the Officer acted as a Company employee in
an intentionally wrongful or tortuous manner toward another employee, customer, supplier or prospective customer or supplier; or (vi) conviction of a crime in connection with illegal drug or substance abuse or illegal drug or substance addiction on
the part of the Officer. For purposes of this Agreement, “without Cause” shall mean a termination by the Company of the Officer’s employment during the Employment Period for any reason other than a termination based upon Cause,
death or Disability. 
  
 (ii) Good Reason.
The Officer may terminate the Officer’s employment during the Employment Period for Good Reason or without Good Reason. For purposes of this Agreement, “Good Reason” shall mean a breach by the Company of the Company’s
material terms or conditions of this Agreement which constitute a material nonperformance by the Company of its obligations and duties under this Agreement that is not cured within ten (10) business days after the Officer’s provision to the
Company of written notice describing the alleged breach. For purposes of this Agreement, “without Good Reason” shall mean a termination by the Officer of the Officer’s employment during the Employment Period for any reason
other than a termination based upon Good Reason. 
  
 (c) Notice of Termination. Any termination by the Company for Cause or without Cause, or by the Officer for Good Reason or without Good Reason, shall be communicated by Notice of Termination to the other party hereto given in
accordance with Section 12(b). For purposes of this Agreement, a “Notice of Termination” means a written notice which (i) indicates the specific termination provision in this Agreement relied upon, (ii) to the extent
applicable, sets forth in reasonable detail the facts and circumstances claimed to provide a basis for termination of the Officer’s employment under the provision so indicated and (iii) if the Date of Termination (as defined below) is other
than the date of receipt of such notice, specifies the termination date (which date shall not be more than 15 days after the giving of such notice). The failure by the Company or Officer to set forth in the Notice of Termination any fact or
circumstance which contributes to a showing of Cause shall not waive any right of the Company or the Officer hereunder or preclude the Company or Officer from asserting such fact or circumstance in enforcing the Company’s or the Officer’s
rights hereunder. Either party may seek review and final determination by an arbitrator if such party wishes to challenge the termination of the Officer’s employment by the Company for Cause or by the Officer for Good Reason in accordance with
Section 12(g). 
  
 (d) Date of
Termination. “Date of Termination” means (i) if the Officer’s employment is terminated by the Company for Cause, or by the Officer for Good Reason or without Good Reason, the date of receipt of the Notice of Termination or
any later date specified therein pursuant to Section 3(c), as the case may be, (ii) if the Officer’s employment is terminated by the Company without Cause, the date on which the Company notifies the Officer 

  

 4 

 
of such termination, and (iii) if the Officer’s employment is terminated by reason of death or Disability, the date of death of the Officer or the
Disability Effective Date, as the case maybe. 
  
 (e) Rights and Obligations Upon Notice of Termination. The foregoing notwithstanding, if the Officer gives notice of termination of this Agreement under this Section 3, or if it becomes known that this Agreement will otherwise
terminate in accordance with its provisions, the Company may, in its sole discretion and subject to its other obligations under this Agreement, immediately relieve the Officer of his duties under this Agreement, in which event the Officer shall have
no further duties or obligations under Section 2(a). 
  
 4.
Obligations of the Company upon Termination. 
  
 (a) Other Than for Cause, Death or Disability. For and in consideration of the Officer’s covenants set forth in Sections 6 through 9 of this Agreement, the Company agrees that if, during the Employment Period, the
Company shall terminate the Officer’s employment other than for any of Cause, death or Disability or the Officer shall terminate the Officer’s employment for Good Reason, the Company shall (i) pay to the Officer in cash within 10 days
after the Date of Termination such portion of the Officer’s Annual Base Salary through the Date of Termination as has not thereto for been paid and any expenses not previously reimbursed in accordance with Section 2(b)(iv) hereof
(collectively, “Accrued Obligations”), and (ii) pay to the Officer or, if applicable, his heirs, executors, or personal representatives, in regular installments in accordance with the customary payroll practices of the Company, an
amount equal to the Officer’s then current Annual Base Salary from the Date of Termination through the end of the current Employment Period (the “Severance Payment”). The Company shall have no further payment obligations to the
Officer under this Agreement, other than for (A) amounts arising from the Officer’s participation in, or benefits under, any plans or programs in which the Officer participated pursuant to Section 2(b)(iii), which amounts shall be
payable in accordance with the terms and conditions of such plans and programs, and (B) bonus payments, if any, of the Change in Net Income and the Gross Profit Bonus calculated based upon the current Period ending on the Date of Termination.

  
 (b) Cause, Death, Disability or
Resignation. If the Officer’s employment shall be terminated by the Company for Cause, death or Disability or the Officer terminates his employment during the Employment Period without Good Reason, the Company shall have no further payment
obligations to the Officer (including no obligation to make the Severance Payment or any bonus payments, if any, of the Change in Net Income and the Gross Profit Bonus for the current Period) other than for Accrued Obligations and for amounts
arising from the Officer’s participation in, or benefits under, any plans or programs in which the Officer participated pursuant to Section 2(b)(iii), which amounts shall be payable in accordance with the terms and conditions of such
plans and programs. The Officer acknowledges that the Officer’s covenants set forth in Sections 6 through 9 of this Agreement shall continue as provided in such Sections following the termination of the Officer’s employment
by the Company for Cause or Disability or by the Officer through his resignation for any reason. 
  
 5. Full Settlement. In no event shall the Officer be obligated to seek other employment or take any other action by way of mitigation of the
amounts payable to the Officer under any of the provisions of this Agreement and such amounts shall not be reduced whether or 

  

 5 

 
not the Officer obtains other employment. Neither the Officer nor the Company shall be liable to the other party for any damages in addition to the amounts
payable under Section 4 arising out of the termination of the Officer’s employment prior to the end of the Employment Period; provided, however, that the Company shall immediately be entitled to seek damages for any breach of
Section 2(c), Sections 6 through 9 or criminal conduct. 
  
 6. Confidential Information. The Company hereby agrees to provide the Officer with, and the Officer hereby acknowledges that, he will be made aware of certain confidential business information, trade secrets,
innovations and inventions, expertise and know-how, customer information and other non-public information concerning the business of Company and the Related Companies (“Confidential Information”), and that such information, even
though it may be contributed, developed or acquired by the Officer, constitutes valuable, special and unique assets of the Company, which are to be held by the Officer in trust and solely for the Company’s benefit. The Officer further
acknowledges that the Confidential Information includes “trade secrets” under the Pennsylvania Uniform Trade Secrets Act (12 Pa. Cons. Stat. Sections 5301-5308) (the “Uniform Trade Secrets Act”). In addition to the other
protections provided herein, all trade secrets shall be accorded the protections and benefits of the Uniform Trade Secrets Act, any other applicable and the common law. 
  
 (a) Confidentiality of Information. The Officer shall not, during the Employment Period and for a
period of two (2) years thereafter, divulge or disclose to any third person, firm or company, or make personal or non-Company use of, any Confidential Information. These obligations of nondisclosure shall not apply to information which:, (i) is in
the public domain or is generally known or available, or hereafter becomes part of the public domain or is generally known or available through no violation of this Agreement; (ii) is henceforth lawfully acquired by the Officer from any third party
not bound, to the actual knowledge of the Officer, by an obligation of confidence to the Company or (iii) is required, pursuant to judicial action or governmental regulations or other requirements, to be disclosed by the Officer, provided
that the Officer has notified the Company of such imminent disclosure and cooperates with the Company in the event that the Company elects to contest and avoid such disclosure. 
  
 (b) Return of Information. Upon termination or expiration of this Agreement, the Officer shall return
to the Company, and will not keep in his possession, all documents, drawings, computer files or any other information in tangible form, whether confidential or not, concerning the business or operations of the Company or the Related Companies.

  
 (c) Non-Disparagement. Upon
termination of this Agreement, the Officer shall not make, except as required by judicial, legislative or administrative process or governmental rule or regulation, public or private comments about or relating to Company or its board of directors or
the members thereof, officers, owners or management team, where such comments are derogatory or defamatory, or may tend to injure in business, public or private affairs, regardless of whether the same relate to matters of fact or to matters of
personal opinion. 
  
 7. Conflicts of Interest. The Officer
shall not, during the Employment Period and for two (2) years following the expiration or termination of the Employment Period for any reason, or if later and applicable to the termination, the due date of the final Severance Payment 

  

 6 

 
pursuant to Section 4(a) (the “Restricted Period”), directly or indirectly become involved in any conflict of interest related to the
Business (as defined below in Section 9), including ownership of an interest in any competitor of the Company or any supplier, contractor, subcontractor, customer or other entity with which the Company does business or accept any payment,
service, gift, loan or other favor from any such entities; provided, however, that the Officer may own, solely as an investment, up to five percent (5%) of any securities of any publicly traded partnership, trust, corporation or other entity,
provided he remains a passive investor in such entity. Upon discovery of such a conflict of interest, the Officer shall take immediate action to remove the conflict. The Officer shall promptly disclose to the Chief Executive Officer of the
Company any facts or circumstances which might involve or cause an actual conflict of interest, or the appearance of one. 
  
 8. Solicitation of Employees. The Officer shall not during the Restricted Period directly or indirectly solicit for employment, or otherwise
encourage the departure of, any employee of the Company. 
  
 9.
Competition. The Officer shall not, during the Employment Period and during the Restricted Period: (i) carry on or engage in, directly or indirectly, a business similar to the Business (as defined below) of the Company within the State of
Pennsylvania or within any other areas in which the Company operates, whether directly or through an agent, during the Employment Period (collectively, the “Non-Compete Area”), (ii) solicit any direct or indirect customers of the
Company within the Non-Compete Area for a business that competes with the Company, or (iii) own, manage, operate, control or be employed by or participate in the management, ownership, operation or control of, or be connected in any manner with, any
business in the Non-Compete Area of the type and character engaged in by the Company; provided, however, that the Officer may own, solely as an investment, up to five percent (5%) of any securities of any publicly traded partnership, trust,
corporation or other entity, provided he remains a passive investor in such entity. “Business” shall mean developing, wholesaling and distributing a wide variety of non-prescription dietary supplements, vitamins, health food and
nutritional products, soft goods and other related products and such other business activities engaged in by the Company during the Employment Period. 
  
 The Officer agrees that it would not be possible to measure in monetary terms the damages which the Company would incur if the Officer breaches his
obligations under this Section 9. Therefore, if the Company institutes any action or proceedings to enforce its rights hereunder, the Officer agrees that the Company may seek specific performance of the requirements of this Section 9
or temporary or permanent injunctive relief, and that the Officer will not assert, and he hereby does waive forever the claim or defense that the Company has an adequate remedy at law. The Officer further agrees that, if the Officer violates any of
the covenants set forth in this Section 9, the Company will suffer irreparable damage and shall be entitled to full injunctive relief or such other relief against the Officer as may be provided by law or in equity together with such damages
as may be provided at law or in equity. In the event of the Officer’s breach of this Section 9, the Officer further agrees to pay the Company all costs and expenses, including reasonable attorneys’ fees, incurred by the Company in
enforcing its rights hereunder as set forth in Section 12(j). The provisions of this Section 9 are intended to convey enforceable benefits upon the successors and assigns of the Company, and such successors and 

  

 7 

 
assigns are hereby authorized to enforce the provisions of this Section 9 subject to the provisions set forth in Section 11(b). 
  
 The Officer specifically acknowledges and agrees as follows: (A) the
covenants contained in this Section 9 are reasonable and necessary to protect the Confidential Information, goodwill and the operations and legitimate business interests of the Company, (B) the time duration of such covenants are reasonable
and necessary to protect the Confidential Information, goodwill and the operations and legitimate business interests of the Company, (C) the geographical area limitations of such covenants are reasonable and necessary to protect Confidential
Information, goodwill and the operations and legitimate business interests of the Company and (D) such covenants are not oppressive to the Officer and do not impose a greater restraint on the Officer than is necessary to protect the Confidential
Information, goodwill and the operations and legitimate business interests of the Company. 
  
 It is the express intention of the Company and the Officer to comply with all laws which may be applicable to the covenants in Section 9 of this Agreement. Therefore, the Company and the Officer have attempted
to limit the Officer’s right to compete only to the extent necessary to protect (i) the Company from unfair competition and (ii) the Company’s Confidential Information, goodwill and its operations and business. Consequently, the Company
and the Officer hereby specifically agree that, in the event that any covenant contained in Section 9 of this Agreement shall be determined by any court, arbitrator or other constituted legal authority to be effective in any particular area
or jurisdiction only if such covenant is modified to limit its duration or scope, such covenant may be reformed or modified by the judgment or order of such court, arbitrator or authority to reflect a lawful and enforceable duration and scope. Such
covenant automatically shall be deemed to be amended and modified with respect to that particular area or jurisdiction so as to comply with the judgment or order of such court, arbitrator or authority and, as to all other areas and jurisdictions
covered by this Agreement, the terms and provisions hereof shall remain in full force and effect as originally written. If any covenants contained in this Section 9 shall be held by any court, arbitrator or other constituted legal authority
to be void or otherwise unenforceable in any particular area or jurisdiction notwithstanding the operation of this provision, such covenant automatically shall be deemed to be amended so as to eliminate therefrom that particular area or jurisdiction
as to which such covenant is so held void or otherwise unenforceable and, as to all other areas and jurisdictions covered by this Agreement, the terms and provisions hereof shall remain in full force and effect as originally written. Notwithstanding
the foregoing, nothing in this Section or the Agreement is intended in any way to limit the Officer’s right to defend, challenge or contest any action brought by the Company or to counterclaim against the Company in any court proceeding
instituted by the Company. 
  
 10. Remedies. With regard to
Sections 6 through 9: 
  
 (a) The
Officer acknowledges that: (i) the covenants of the Officer in Sections 6 through 9 (“Covenants”) contain limitations as to geography, time and scope which are reasonable and do not impose a greater restraint than is
necessary to protect Company, the Related Companies and their respective affiliates from direct financial harm, (ii) the Covenants are ancillary to the other provisions of this Agreement, particularly the provisions of Section 6 concerning
confidentiality and return of Company property and (iii) the disclosure of 

  

 8 

 
Confidential Information contrary to Section 6 would in all likelihood be inevitable during the course of any breach of Section 9. 

 
 (b) The Officer’s obligations in Sections 6
through 9 shall be deemed cumulative of any other related obligations between the Officer and Company that may co-exist as of the effective date of this Agreement. 
  
 (c) If the Officer breaches, or threatens to commit a breach of, any of the provisions of Sections 6
through 9, the Company shall have the following rights and remedies, each of which rights and remedies shall be in addition to, and not in lieu of, any other rights and remedies available to the Company at law or in equity: 
  
 (i) Specific Performance. The right and remedy to
have the provisions of Sections 6 through 9 specifically enforced by any court having jurisdiction, and the Officer hereby consents that temporary or permanent injunctive relief may be granted, all without the need to post a bond or
any other security or to prove actual damage or that money damages would not provide an adequate remedy, it being acknowledged and agreed that any such breach or threatened breach will in all likelihood cause immediate and irreparable injury to the
Company for which monetary damages would not provide an adequate remedy; and 
  
 (ii) Accounting and Indemnification. The right and remedy to require the Officer (A) to account for and pay over to the Company all compensation, profits, monies, accruals, increments or other benefits derived
or received by the Officer or any associated party deriving such benefits as a result of any such breach of the provisions of Sections 6 through 9, and (B) to indemnify the Company against any other losses, damages, costs and expenses,
including actual attorneys fees and court costs as set forth in Section 12(j), which may be incurred by it and which result from or arise out of or relate to any such breach or threatened breach of the provisions of Sections 6 through
9. 
  
 (d) In the event that the Officer
breaches any of the covenants contained in Section 9, the running of the two (2) year period specified in Section 9 shall be tolled for so long as such breach continues. 
  
 11. Successors. 
  
 (a) This Agreement is personal to the Officer and shall not be assignable by the Officer. This Agreement shall inure to the benefit of and
be enforceable by the Officer’s legal representatives. 
  
 (b) This Agreement shall inure to the benefit of and be binding upon the Company and its successors and assigns. THE OFFICER ACKNOWLEDGES AND AGREES THAT THE COMPANY MAY ASSIGN THE AGREEMENT TO ANY SUCCESSOR TO ITS
BUSINESS. By Officer acknowledging and agreeing to the Company’s right of assignment, the Officer is not extending or enlarging any of the restrictions and/or limitations imposed upon him pursuant to Sections 6 through 9 of this
Agreement and there are no rights being given to any assignee by the Officer in addition to those given to the Company pursuant to this Agreement. 
  

 9 

 12. Miscellaneous. 
  
 (a) Governing; Law. This Agreement shall be subject to and governed by the laws of the Commonwealth
of Pennsylvania, excluding any conflicts of law rule or principle that might refer the construction hereof to the laws of another state. 
  
 (b) Notices. All notices and other communications hereunder shall be in writing and shall be deemed given if delivered personally,
telecopied, mailed by registered or certified mail (return receipt requested) or sent by Federal Express or other recognized overnight courier guaranteeing next business day delivery, to the parties at the following addresses (or at such other
address for a party as shall be specified by like notice): 
  
 if
to the Company, to: 
  
 Bob O’Leary Health Food Distributor
Co., Inc. 
 6911 Bryan Dairy Road, Suite 210 
 Largo, Florida 33777 
 Attention: Mandeep Taneja 
 Telephone No.: (727) 329-1845 
 Facsimile No.:
(727) 329-1846 
  
 if to the Officer, to: 
  
 Mr. Joseph Mies 
 77 Cranberry Terrace 
 Duryea, PA 18642

 Telephone No.: (570) 655-8761 
  
 Any of the above addresses may be changed at any time by notice given as provided above; provided, however, that any such notice or
change of address shall be effective only upon receipt. All notices, requests or instructions given in accordance herewith shall be deemed received on the date of delivery, if hand delivered, on the date of receipt, if telecopied during the
recipient’s normal business hours and if a telecopy confirmation is received, three (3) business days after the date of mailing, if mailed by registered or certified mail, return receipt requested, and one business day after the date of
sending, if sent by Federal Express or other recognized overnight courier. 
  
 (c) Amendments. Any provision of this Agreement may be amended or waived if, and only if, such amendment or waiver is in writing and signed, in the case of an amendment, by the Company and the Officer or, in
the case of a waiver, by the party against whom the waiver is to be effective. 
  
 (d) No Waivers. No failure or delay by any party in exercising any right, power or privilege hereunder shall operate as a waiver
thereof nor shall any single or partial exercise thereof preclude any other or further exercise thereof or the exercise of any other right, power or privilege. The rights and remedies herein provided shall be cumulative and not exclusive of any
rights or remedies provided by law. 
  

 10 

 (e) Counterparts; Effectiveness. This Agreement may be signed in any number of
counterparts, each of which shall be an original, with the same effect as if the signatures thereto and hereto were upon the same instrument. This Agreement shall become effective when each party hereto shall have received counterparts hereof signed
by the other party hereto. 
  
 (f)
Severability. If any term or other provision of this Agreement is determined by a court of competent jurisdiction to be invalid, illegal, or incapable of being enforced under any rule of applicable law or public policy, all other conditions
and provisions of this Agreement shall nevertheless remain in full force and effect so long as the economic or legal substance of the transactions contemplated herein are not affected in any manner materially adverse to any party. Upon such
determination that any term or other provision is invalid, illegal, or incapable of being enforced, the parties hereto shall negotiate in good faith to modify this Agreement so as to effect the original intent of the parties as closely as possible
in a mutually acceptable manner in order that the transactions contemplated herein are consummated as originally contemplated to the fullest extent possible. 
  

(g) Arbitration. By signing this Agreement, the Officer acknowledges that any claim arising out of or relating to this Agreement
or the breach of this Agreement or your employment by the Company must be submitted and resolved by, binding arbitration except that any claim by the Company for which it seeks an injunction or other equitable relief (Sections 9 and 10) shall not be
submitted to or subject to arbitration unless you and the Company agree otherwise in writing. You understand that you and the Company are agreeing to submit all other claims to arbitration. All questions pertaining to the arbitrability of a
particular claim or defense shall be determined by the arbitrator or arbitrators. Any such arbitration will be administered by the American Arbitration Association under its Employment Arbitration Rules at Philadelphia, Pennsylvania. The award
entered by the arbitrator will be final and binding in all respects. EXCEPT AS PROVIDED IN SECTIONS 9 AND 10, THIS AGREEMENT IS A WAIVER OF ALL RIGHTS TO A CIVIL COURT ACTION, AND ONLY THE ARBITRATORS, NOT A JUDGE OR JURY, WILL DECIDE
SUCH DISPUTE. 
  
 (h) Forum for
Litigation. Any action at law or in equity arising out of or relating to this Agreement and permitted under Section 12(g) shall occur in the Court of Common Pleas of Lackawanna County, Pennsylvania, or the United States District Court for
the Middle District of Pennsylvania, and, for purposes of any such action, the parties hereby expressly consent and agree to be subject to and to submit themselves to the jurisdiction of the courts in such location. 
  
 (i) Survival. Sections 2(c), 6 through
10 and 12 of this Agreement shall survive the termination of this Agreement. 
  
 (j) The prevailing party in any legal or arbitration proceeding brought under or to enforce this Agreement shall be entitled to recover
court and or arbitration costs and reasonable attorneys’ fees from the non-prevailing party. 
  
 (k) Interpretation. The following provisions shall be applied wherever appropriate herein: (i) “herein,”
“hereby,” “hereunder,” “hereof,” “hereto” and other equivalent words shall refer to this Agreement as an entirety and not solely to the particular portion of this 

  

 11 

 
Agreement in which any such word is used, (ii) “including” means “including without limitation” and is a term of illustration and not of
limitation (iii) all definitions set forth herein shall be deemed applicable whether the words defined are used herein in the singular or the plural, (iv) wherever used herein, any pronoun or pronouns shall be deemed to include both the singular and
plural and to cover all genders, (v) neither this Agreement nor any other agreement, document or instrument referred to herein or executed and delivered in connection herewith shall be construed against any person as the principal draftsperson
hereof or thereof, (vi) the section headings appearing in this Agreement are inserted only as a matter of convenience and in no way define, limit, construe or describe the scope or extent of such section, or in any way affect this Agreement and
(vii) any reference herein to a particular Section, Article, Exhibit or Schedule means a Section or Article of, or an Exhibit or Schedule to, this Agreement unless another agreement is specified. 
  
 (l) Legal Review. The Officer acknowledges and agrees
that he has had reasonable time to consider the terms of this Agreement, has had an opportunity to consult with an attorney of his own choosing, and has relied fully and completely on his own judgment and the advice of his attorneys in deciding
whether to execute this Agreement. 
  
 (m)
Entire Agreement. This Agreement contains, and is intended as, and represents a complete statement of all of the terms, understandings and the arrangements among the parties hereto with respect to the matters provided for herein, supersede
any previous or contemporaneous agreements and understandings whether oral or written between the parties hereto with respect to those matters and cannot be changed or terminated except as provided in this Agreement. 
  
 Remainder of page intentionally left blank; 
 signature page follows. 
  

 12 

 IN WITNESS WHEREOF, the Officer has hereunto set the Officer’s hand and, pursuant to the
authorization from the Board of Directors, the Company has caused this Agreement to be executed in its name on its behalf, all as of the day and year first above written. 
  

	
	OFFICER:
	
	/s/    JOSEPH MIES        
	Joseph Mies

  

			
	COMPANY:
	
	Bob O’Leary Health Food Distributor Co., Inc.,
		
	 By:
	 	/s/    MANDEEP K. TANEJA        
	 Name:
	 	Mandeep K. Taneja
	 Title:
	 	CEO & President

  
 Employment Agmt (Mies)
(Execution Copy)

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