Document:

EXHIBIT 4.2

THE SECURITIES REPRESENTED HEREBY HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), OR UNDER THE SECURITIES LAWS OF ANY STATE.  THESE SECURITIES ARE SUBJECT TO RESTRICTIONS ON
TRANSFERABILITY AND RESALE AND MAY NOT BE TRANSFERRED OR RESOLD EXCEPT AS PERMITTED UNDER THE ACT AND THE APPLICABLE STATE SECURITIES LAWS, PURSUANT TO REGISTRATION OR EXEMPTION THEREFROM.  THE ISSUER OF THESE SECURITIES MAY REQUIRE AN OPINION OF COUNSEL IN FORM
AND SUBSTANCE SATISFACTORY TO THE ISSUER TO THE EFFECT THAT ANY PROPOSED TRANSFER OR RESALE IS IN COMPLIANCE WITH THE ACT AND ANY APPLICABLE STATE SECURITIES LAWS.

SANGSTAT MEDICAL CORPORATION

Warrant for the Purchase of Shares of Common Stock

No.       
                                                                                                                        
-50,000 Shares-

                        FOR VALUE RECEIVED, SANGSTAT MEDICAL CORPORATION, a  Delaware corporation (the "Company"), with its principal office at
6300 Dumbarton Circle, Fremont, California 94555, hereby certifies that HighbridgeInternational LLC or its registered assigns (the "Holder") is entitled, subject to the provisions of this Warrant, to purchase from
the Company, the number of fully paid and nonassessable shares of Common Stock of the Company set forth above. 

                        This Warrant shall be exercisable, in whole or in part, at any time or from time to time after the date hereof and on or before
5:00 p.m. California time on April 25, 2005; provided, however, that in the event of (a) the closing of the Company's sale or transfer of all or substantially all of its assets or (b) the closing of the acquisition of the Company by another entity by means of merger,
consolidation or other transaction or series of related transactions, resulting in the exchange of the outstanding shares of the Company's capital stock such that the stockholders of the Company prior to such transaction own, directly or indirectly, less than 50% of
the voting power of the surviving entity, this Warrant shall, on the date of such event, no longer be exercisable and become null and void.  In the event of a proposed transaction of the kind described above, the Company shall notify the holder of the Warrant at
least five (5) days prior to the closing of such event or transaction.

                        The Holder may purchase the above number of shares of Common Stock at a purchase price per share (as appropriately adjusted
pursuant to Section 6 hereof) of $23.438 (the "Exercise Price").  The term "Common Stock" shall mean the aforementioned Common Stock of the Company, together with any other equity securities that may be issued by the Company in addition thereto or in
substitution therefor as provided herein.

                        The number of shares of Common Stock to be received upon the exercise of this Warrant and the price to be paid for a share of
Common Stock are subject to adjustment from time to time as hereinafter set forth.  The shares of Common Stock deliverable upon such

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exercise, as adjusted from time to time, are hereinafter sometimes referred to as "Warrant Shares".

                        This Warrant is issued pursuant to that certain Letter Agreement between the Company and Reedland Capital Partners, dated November
29, 1999 (the "Agreement") in satisfaction of the Company's obligations under the Agreement.

                        Section 1.         Exercise of Warrant. 

                        (a)        The Holder may exercise the Warrant in whole or in part on any business day prior
to the termination of the Warrant by presentation and surrender hereof to the Company at its principal office at the address set forth in the initial paragraph hereof (or at such other address as the Company may hereafter notify the Holder in writing) with the
Purchase Form annexed hereto duly executed and accompanied by proper payment of the Exercise Price in lawful money of the United States of America in the form of cash, or a certified or cashier's check for the number of Warrant Shares specified in the Purchase
Form.  If this Warrant should be exercised in part only, the Company shall, upon surrender of this Warrant, execute and deliver a new Warrant evidencing the rights of the Holder thereof to purchase the balance of the Warrant Shares purchasable hereunder. 
Upon receipt by the Company of this Warrant and such Purchase Form, together with proper payment of the Exercise Price, at such office, the Holder shall be deemed to be the holder of record of the Warrant Shares, notwithstanding that the stock transfer books of the
Company shall then be closed or that certificates representing such Warrant Shares shall not then be actually delivered to the Holder.  The Company shall pay any and all documentary stamp or similar issue or transfer taxes payable in respect of the issue or
delivery of the Warrant Shares.

                        (b)        Notwithstanding the foregoing, upon such exercise pursuant to Section 1(a), in
lieu of payment of the Exercise Price, the Holder may instead elect to receive that number of shares of Common Stock of the Company equal to the quotient obtained by dividing [(A-B)(C)] by A, where:

                                    (A)      
=          the Fair Market Value (as defined below) of one share of Common Stock on the date of exercise of this Warrant;

                                    (B)      
=          the Exercise Price for one share of Common Stock under this Warrant (as adjusted to the date of such calculation); and

                                    (C)      
=          the number of shares of Common Stock issuable upon exercise of this Warrant or, if only a portion of the Warrant is being exercised, the portion of the Warrant being canceled (at the date of such
calculation).

If the above calculation results in a negative number, then no shares of Common Stock shall be issued or issuable upon exercise of this Warrant pursuant to this Section 1(b).

            For purposes hereof, "Fair Market Value" of a share of Common Stock shall mean:

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(A)  where there exists a public market for the Company's Common Stock at the time of such exercise, the fair market value per share of Common Stock shall be the average of the closing bid and asked prices of the Common Stock quoted in the Over-The-Counter
Market Summary or the last reported sale price of the Common Stock or the closing sale price quoted on the NASDAQ National Market System or on any exchange on which the Common Stock is listed, whichever is applicable; or

                                               
(B)   in all other cases, the fair value as determined in good faith by the Company's Board of Directors.

            Upon exercise of this Warrant pursuant to this Section 1(b), the registered holder hereof shall be entitled to receive a certificate for the number of shares of Common Stock determined as aforesaid
within a reasonable time not to exceed twenty (20) days after exercise of the stock purchase rights represented by this Warrant.

                        Section 2.         Reservation of Shares.  The Company hereby agrees that at
all times there shall be reserved for issuance and delivery upon exercise of this Warrant all shares of its Common Stock or other shares of capital stock of the Company from time to time issuable upon exercise of this Warrant.  All such shares shall be duly
authorized and, when issued upon such exercise in accordance with the terms of this Warrant, shall be validly issued, fully paid and nonassessable, free and clear of all liens, security interests, charges and other encumbrances or restrictions on sale (other than as
provided in the Company's certificate of incorporation and any restrictions on sale or transfer set forth herein or pursuant to applicable federal and state securities laws) and free and clear of all preemptive rights.

                        Section 3.         Fractional Interest.  The Company will not issue a
fractional share of Common Stock upon exercise of a Warrant.  Instead, the Company will deliver its check for the fair market value of such fraction of a share, rounded to the nearest cent.

                        Section 4.         Representations and Warranties of the Holder.  The Holder
hereby represents, warrants and covenants with the Company as follows:

                                    (a)        The Holder
is acquiring the Warrant and the Warrant Shares for its own account, not as nominee or agent, for investment and not with a view to, or for resale in connection with, any distribution or public offering thereof within the Act;

                                    (b)       
The Holder understands that the Warrant Shares have not been registered under the Act by reason of a specific exemption therefrom, that such securities must be held by the Holder indefinitely unless the Warrant Shares are subsequently registered
under the Act and qualified under any applicable state securities laws, or unless exemptions from registration and qualification are otherwise available.  The Holder also understands that the Company is issuing this Warrant in reliance upon the Holder's
representations and warranties contained herein, and that any federal or state exemption is contingent upon the accuracy of the Holder's representations and warranties contained herein; and

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                                    (c)       
The Holder is an “accredited investor” as such term is defined in Rule 501 of the Act and was not formed for the specific purpose of acquiring this Warrant or the  Warrant Shares.

                        Section 5.         Rights of the Holder.  The Holder shall not, by
virtue hereof, be entitled to any rights of a shareholder in the Company, either at law or equity, and the rights of the Holder are limited to those expressed in this Warrant.  Nothing contained in this Warrant shall be construed as conferring upon the Holder
hereof the right to vote or to consent or to receive notice as a shareholder of the Company on any matters or any rights whatsoever as a shareholder of the Company.  No dividends or interest shall be payable or accrued in respect of this Warrant or the interest
represented hereby or the Warrant Shares purchasable hereunder until, and only to the extent that, this Warrant shall have been exercised in accordance with its terms.

                        Section 6.         Adjustment of Exercise Price and Number of Shares.  The
number and kind of securities purchasable upon the exercise of each Warrant and the Exercise Price shall be subject to adjustment from time to time upon the happening of certain events, as follows:

                                    (a)       
Adjustment for Change in Capital Stock.  If the Company:

                                               
(A)  pays a dividend or makes a distribution on its Common Stock in shares of its Common Stock;

                                               
(B)  subdivides its outstanding shares of Common Stock into greater number of shares;

                                               
(C)  combines its outstanding shares of Common Stock into a smaller number of shares;

                                               
(D)  makes a distribution on its Common Stock in shares of its capital stock other than Common Stock; or

                                               
(E)  issues by reclassification of its Common Stock any shares of its capital stock;

then the exercise right and the Exercise Price in effect immediately prior to such action shall be adjusted so that the Holder may receive upon exercise of the Warrants the number of shares of capital stock of the Company which the Holder would have owned immediately
following such action if the Holder had exercised the Warrants immediately prior to such action.

                        The adjustment shall become effective immediately after the record date in the case of a dividend or distribution and
immediately after the effective date in the case of a subdivision, combination or reclassification.

                                    (b)        Notice
of Adjustments.  Whenever the Exercise Price or number of Warrant Shares issuable upon exercise hereof shall be adjusted pursuant to this section, the

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Company shall provide notice of the event requiring the adjustment, the amount of the adjustment, the
method by which such adjustment was calculated and the Exercise Price and number of Warrant Shares purchasable hereunder after giving effect to such adjustment.

                                    (c)       
Deferral of Issuance or Payment.  In any case in which an event covered by this Section 6 shall require that an adjustment in the Exercise Price be made effective as of a record date, the Company may elect to defer until the occurrence of such event (i)
issuing to the Holder, if this Warrant is exercised after such record date, the shares of Common Stock and other capital stock of the Company, if any, issuable upon such exercise over and above the shares of Common Stock or other capital stock of the Company, if any,
issuable upon such exercise on the basis of the Exercise Price in effect prior to such adjustment, and (ii) paying to the Holder by check any amount in lieu of the issuance of fractional shares pursuant to Section 3.

                                    (d)        When No
Adjustment Required.  No adjustment need be made for a change in the par value or no par value of the Common Stock.

                                    (e)        Notice
of Certain Actions.  In the event that:

                                               
(A)   the Company shall authorize the issuance to all holders of its Common Stock of rights, warrants, options or convertible securities to subscribe for or purchase shares of its Common Stock or of any other subscription rights, warrants, options or convertible
securities; or

                                               
(B)  the Company shall authorize the distribution to all holders of its Common Stock of evidences of its indebtedness or assets (other than dividends paid in or distributions of the Company's capital stock for which the Exercise Price shall have been adjusted
pursuant to subsection (a) of this Section 6 or regular cash dividends or distributions payable out of earnings or earned surplus and made in the ordinary course of business); or

                                               
(C)  the Company shall authorize any capital reorganization or reclassification of the Common Stock (other than a subdivision or combination of the outstanding Common Stock and other than a change in par value of the Common Stock) or of any consolidation or
merger to which the Company is a party and for which approval of any stockholders of the Company is required (other than a consolidation or merger in which the Company is the continuing corporation and that does not result in any reclassification or change of the
Common Stock outstanding), or of the conveyance or transfer of the properties and assets of the Company as an entirety or substantially as an entirety; or

                                               
(D)   the Company is the subject of  a voluntary or involuntary dissolution, liquidation or winding-up procedure; or

                                               
(E)  the Company proposes to take any action (other than actions of the character described in subsection (a) or (b) of this Section 6) that would require an adjustment of the Exercise Price pursuant to this Section 6;

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then the Company shall cause to be mailed by first-class mail to the Holder, at least five (5) days prior to the applicable record or effective date hereinafter specified, a notice stating (x) the date as of which the holders of Common Stock of record to be entitled
to receive any such rights, warrants or distributions are to be determined, or (y) the date on which any such consolidation, merger, conveyance, transfer, dissolution, liquidation or winding-up is expected to become effective, and the date as of which it is expected
that holders of Common Stock of record shall be entitled to exchange their shares of Common Stock for securities or other property, if any, deliverable upon such reorganization, reclassification, consolidation, merger, conveyance, transfer, dissolution, liquidation
or winding-up.

                                    (f)        
Common Stock Defined.  Whenever reference is made in this Section 6 to the issue of shares of Common Stock, the term "Common Stock" shall include any equity securities of any class of the Company hereinafter authorized which shall not be limited to a
fixed sum or percentage in respect of the right of the holders thereof to participate in dividends or distributions of assets upon the voluntary or involuntary liquidation, dissolution or winding-up of the Company.  However, shares issuable upon exercise hereof
shall include only shares of the class designated as Common Stock of the Company as of the date hereof or shares of any class or classes resulting from any reclassification or reclassifications thereof or as a result of any corporate reorganization.

                                    (g)        No
Adjustment Upon Exercise of Warrants.  No adjustments shall be made under any Section herein in connection with the issuance of Warrant Shares upon exercise of the Warrants.

                        Section 7.  Assignment or Loss of Warrant.

                                    (a)        Except as
otherwise provided herein, the Holder of this Warrant shall not be entitled, without obtaining the consent of the Company, to transfer, assign or sell its interest in this Warrant in whole or in part to any person or persons; provided, however, that this warrant may
be assigned to affiliates, (including distributions or transfers made to general or limited partners of a Holder) in compliance with the provisions of Section 8.  Subject to the provisions of Section 8, and the obtaining of such consent of the Company, where
required, upon surrender of this Warrant to the Company or at the office of its stock transfer agent or warrant agent, with the Assignment Form annexed hereto duly executed and funds sufficient to pay any transfer tax, the Company shall, without charge, execute and
deliver a new Warrant or Warrants in the name of the assignee or assignees named in such instrument of assignment and, if the Holders entire interest is not being assigned, in the name of the Holder, and this Warrant shall promptly be canceled.

                                    (b)        Upon
receipt of evidence satisfactory to the Company of the loss, theft, destruction or mutilation of this Warrant, and (in the case of loss, theft or destruction) of indemnification satisfactory to the Company, and upon surrender and cancellation of this Warrant, if
mutilated, the Company shall execute and deliver a new Warrant of like tenor and date.

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                        Section 8.         Transfer.  This Warrant may not be exercised and neither
this Warrant nor any of the Warrant Shares, nor any interest in either, may be sold, assigned, pledged, hypothecated, encumbered or in any other manner transferred or disposed of, in whole or in part, without the prior written consent of the Company and in compliance
with applicable United States federal and state securities or blue sky laws and the terms and conditions hereof.  Each Warrant shall bear a legend in substantially the same form as the legend set forth on the first page of this Warrant.  Each certificate
for Warrant Shares issued upon exercise of this Warrant, unless at the time of exercise such Warrant Shares are acquired pursuant to a registration statement that has been declared effective under the Act, shall bear a legend substantially in the following
form:

            THE SECURITIES REPRESENTED HEREBY HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), OR UNDER THE SECURITIES LAWS OF ANY STATE.  THESE SECURITIES ARE SUBJECT TO
RESTRICTIONS ON TRANSFERABILITY AND RESALE AND MAY NOT BE TRANSFERRED OR RESOLD EXCEPT AS PERMITTED UNDER THE ACT AND THE APPLICABLE STATE SECURITIES LAWS, PURSUANT TO REGISTRATION OR EXEMPTION THEREFROM.  THE ISSUER OF THESE SECURITIES MAY REQUIRE AN OPINION OF
COUNSEL IN FORM AND SUBSTANCE SATISFACTORY TO THE ISSUER TO THE EFFECT THAT ANY PROPOSED TRANSFER OR RESALE IS IN COMPLIANCE WITH THE ACT AND ANY APPLICABLE STATE SECURITIES LAWS.

Any certificate for any Warrant Shares issued at any time in exchange or substitution for any certificate for any Warrant Shares bearing such legend (except a new certificate for any Warrant Shares issued after the acquisition of such Warrant Shares pursuant to a
registration statement that has been declared effective under the Act) shall also bear such legend unless, in the opinion of counsel for the Company, the Warrant Shares represented thereby need no longer be subject to the restriction contained herein.  The
provision of this Section 8 shall be binding upon all subsequent holders of certificates for Warrant Shares bearing the above legend and all subsequent holders of this Warrant, if any.

                        Section 9.         Modification and Waiver.  This Warrant and any term hereof may
be changed, waived, discharged or terminated by an instrument in writing signed by the Company and by the Holders of a majority of the Warrants (on the basis of the number of Warrant Shares into which such Warrants then outstanding are exercisable) issued pursuant to
the Agreement.  Any amendment effected in accordance with this Section 9 shall be binding upon each Holders of any of the Warrants, each future Holders of all such Warrants, and the Company; provided, however, that no special consideration or inducement may be
given to any such Holders in connection with such consent that is not given ratably to all such Holders, and that such amendment must apply to all such Holders equally and ratably in accordance with the number of shares of Common Stock issuable upon exercise of their
Warrants.

                        Section 10.       Notices. All notices and other communications required or permitted
hereunder shall be in writing and shall be deemed effectively given upon personal delivery, on the first business day following mailing by overnight courier, or on the fifth day following mailing by registered or certified mail, return receipt requested, postage
prepaid,

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addressed to the Company and the Holder at its address as shown on the books of the Company or to the Company at the address indicated therefor in the first paragraph of this Warrant.

                        Section 11.       Descriptive Headings and Governing Law.  The description headings of
the several sections and paragraphs of this Warrant are inserted for convenience only and do not constitute a part of this Warrant.  This Warrant shall be construed and enforced in accordance with, and the rights of the parties shall be governed by, the laws of
the State of California.

                        Section 12.       Successors and Assigns.  The terms and provisions of this Warrant
shall inure to the benefit of, and be binding upon, the Company and the Holders hereof and their respective successors and assigns.

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                        IN WITNESS WHEREOF, the Company and the Holder have duly caused this Warrant to be executed and to be dated as of November 26,
2001. 

                                                                       
SANGSTAT MEDICAL CORPORATION

                                                                       
By:       /s/ Stephen G. Dance                           

                                                                       
Name:  Stephen G. Dance                                 

                                                                       
Title:      Senior Vice President, Finance             

                                                                       
HIGHBRIDGE INTERNATIONAL LLC

                                                                       
By:       HIGHBRIDGE CAPITAL

                                                                                   
MANAGEMENT, LLC

                                                                       
By:       /s/ Carolyn
Rubin                                 

                                                                        
Name:  Carolyn Rubin                                     

                                                                       
Title:      Director of
Legal                                 

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PURCHASE FORM

                                                                                               
Dated ________________, ____

[   ]       The undersigned hereby elects to exercise the within Warrant to purchase ___________ shares of the Common Stock of the Company (the "Shares") at a purchase price of _______________ Dollars
($                ) per Share or an aggregate purchase price of _____________ Dollars ($                )
(the "Purchase Price").

[   ]       The undersigned hereby elects to convert ___________ percent (    %) of the value of the Warrant pursuant to the provisions of Section 1(b) of the Warrant.

            Pursuant to the terms of the Warrant the undersigned has delivered the Purchase Price herewith in full in cash or by certified check or wire transfer.

 

                                                                       
Very truly yours,

                                                                       
________________________________________

                                                                       
By: _____________________________________

                                                                       
Title:____________________________________

 

 

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ASSIGNMENT FORM

                                                                                               
Dated ________________, ____

                        FOR VALUE RECEIVED, ___________________________ hereby

 sells, assigns, and transfers unto ______________________________ (the "Assignee"),

                                                           
(please type or print in block letters)

_______________________________________________________________________

                                                           
(insert address)

its right to purchase up to ____ shares of Common Stock represented by this Warrant and does hereby irrevocably constitute and appoint ____________________ as its attorney-in-fact, to transfer the same on the books of the Company, with full power of substitution in
the premises. 

 

                                                                                   
___________________________________

                                                                                                                 (Signature)

11[FORM OF CHANGE OF CONTROL AGREEMENT]

EXHIBIT 10.17

[Form of Change of Control Agreement]

            This Change of Control Agreement (the “Agreement”) is effective as of _________________ (the “Effective Date”), by and
between_________________ (the “Employee”), and SangStat Medical Corporation  (the “Company”).

RECITALS

            A.        The Employee is presently employed by the Company and performs significant strategic and management responsibilities necessary to the continued conduct of
the Company’s business and operations.

            B.         The Board of Directors of the Company (the “Board”) has determined that it is in the best interests of the Company and its stockholders
to assure that the Company will have the continued dedication and objectivity of the Employee, notwithstanding the possibility or occurrence of a Change of Control (as defined below) of the Company.

            C.        The Board believes that it is imperative to provide the Employee with certain severance benefits upon the Employee’s termination of employment under
the circumstances described herein which provide the Employee with enhanced financial security and provide sufficient incentive and encouragement to the Employee to remain with the Company following a Change of Control.

            D.        Certain capitalized terms used in the Agreement are defined in Section 3 below.

            In consideration of the mutual covenants herein contained the parties agree as follows:

         1.            Terms of Employment.  The Company and the Employee agree that the Employee’s employment is at will, and that his or her
employment relationship may be terminated by either party at any time, with or without cause.  If the Employee’s employment terminates for any reason within one (1) month prior to, upon or within eighteen (18) months following a Change of Control, the
Employee shall not be entitled to any payments, benefits, damages, awards or compensation other than as provided by this Agreement.

         2.            Severance Benefits.

                        (a)        Termination Upon A Change of Control.  If the Employee’s
employment is terminated within one (1) month prior to, upon or within eighteen (18) months following a Change of Control, either by the Company, other than a Termination for Cause, or by the Employee as a result of an Involuntary Termination (as defined in Section
3(b) below), then the Employee shall be entitled to receive the compensation, accrued but unused vacation and benefits earned by the Employee through the date of the Employee’s termination of employment and in addition thereto the following severance benefits,
as applicable:

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                                    (i)        
Severance Pay.  Severance pay in an amount equal to (x) ________________1 times (i) the Employee’s annual base salary at the time of such termination and (ii) any bonuses received by the Employee over the twelve (12) months
immediately prior to the termination date, plus (y) an amount equal to a portion of the incentive bonus, if any, the Employee will have earned for the fiscal year of the termination on the basis of the achievement of the agreed upon goals for the fiscal year of the
termination pro rated to the date of termination, to be paid in a lump sum within thirty (30) days of the Employee’s termination; provided, however, that Employee may elect to receive the salary part of the severance pay as salary continuation over the next
_________________.2

                                     (ii)       
Options.  All options previously granted to Employee shall become immediately exercisable and vested in full as of Employee’s termination date;

                                     (iii)      
Outplacement.  Employee may receive outplacement services for the sooner of six months or until the Employee commences new employment, at a mutually agreed-upon vendor up to a value of [$5,000-$15,000], which amount shall be paid directly from the Company
to the vendor; and

                                    (iv)      
COBRA.  For a period of up to _________________3 after any termination under this Section 2(a), the Company shall reimburse the Employee for any COBRA premiums paid by the Employee for continued group health insurance coverage (the
“Employment Benefits”).  If the Employee’s medical coverage immediately prior to the date of termination of employment included the Employee’s dependents, the Company paid COBRA premiums shall include premiums for such dependents. 
Such Employment Benefits, including dependent benefits, shall terminate upon the earlier of (i) _________________ from the date of the Employee’s termination or (ii) upon commencement of new employment by the Employee. 

                         (b)        Voluntary Resignation.  If the Employee’s employment terminates
by reason of the Employee’s voluntary resignation (and is not an Involuntary Termination or a termination for Cause), then the Employee shall not be entitled to receive severance or other benefits following the date of such termination under the terms of this Agreement, and the Company shall have no obligation to provide for the continuation of any health and medical benefit or life insurance plans existing on the date of such termination except as otherwise required by applicable law.

                         (c)        Disability; Death.  If the Company terminates the Employee’s
employment as a result of the Employee’s Disability, or such Employee’s employment is terminated at any time due to the death of the Employee, then the Employee shall not be entitled to receive severance or other benefits following the date of such
termination under the terms of

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this Agreement, and the Company shall have no obligation to provide for the continuation of any health and medical benefit or life insurance plans existing on the date of such termination except as otherwise required by applicable
law.

                         (d)        Termination for Cause.  If the Employee is terminated for Cause (as
defined in Section 3(c) below), then the Employee shall not be entitled to receive any severance or other benefits following the date of such termination under the terms of this Agreement, and the Company shall have no obligation to provide for the continuation of
any health and medical benefit or life insurance plans existing on the date of such termination except as otherwise required by applicable law.

                        [(e)       Limitation of Payments and Benefits.

                                    [(i)        To the
extent that any of the payments and benefits provided for in this Agreement or otherwise payable to the Employee constitute "parachute payments" within the meaning of Section 280G of the Internal Revenue Code of 1986, as amended (the "Code"), and, but for this
Section 2(e), would be subject to the excise tax imposed by Section 4999 of the Code or any similar or successor provision, the aggregate amount of such payments and benefits shall be reduced, but only to the extent necessary so that none of such payments and
benefits are subject to excise tax pursuant to Section 4999 of the Code.

                                    (ii)        Within
sixty (60) days after the later of termination of employment or the related Change in Control, the Company shall notify the Employee in writing if it believes that any reduction in the payments and benefits that would otherwise be paid or provided to the Employee
under the terms of this Agreement is required to comply with the provisions of Subsection 2(e)(i).  If the Company determines that any such reduction is required, it will provide the Employee with copies of the information used and calculations made by the
Company to determine the amount of such reduction.  The Company shall determine, in a fair and equitable manner after consultation with the Employee, which payments and benefits are to be reduced so as to result in the maximum benefit for the Employee.

                                    (iii)       Within thirty
(30) days after the Employee's receipt of the Company's notice pursuant to Subsection 2(e)(ii), the Employee shall notify the Company in writing if the Employee disagrees with the amount of reduction determined by the Company, or the selection of the payments and the
benefits to be reduced.  As part of such notice, the Employee shall also advise the Company of the amount of reduction, if any, that the Employee has, in good faith, determined to be necessary to comply with the provisions of Subsection 2(e)(i) and/or the
payments and benefits to be reduced.  Failure by the Employee to provide this notice within the time allowed will be treated by the Company as acceptance by the Employee of the amount of reduction determined by the Company and/or the payments and benefits to be
reduced.  If any differences regarding the amount of the reduction and/or the payments and benefits to be reduced have not been resolved by mutual agreement within sixty (60) days after the Employee's receipt of the Company's notice pursuant to Subsection
2(e)(ii), the amount of

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reduction and/or the payments and benefits to be reduced as determined by the Employee will be conclusive and binding on both parties unless, prior to the expiration of such sixty (60) day period, the Company notifies the Employee in writing
of the Company's intention to have the matter submitted to arbitration for resolution and proceeds to do so promptly.  If the Company gives no notice to the Employee of a required reduction as provided in Subsection 2(e)(ii), the Employee may unilaterally
determine the amount of reduction required, if any, and/or the payments and benefits to be reduced, and, upon written notice to the Company, the amount and/or the payments and benefits to be reduced will be conclusive and binding on both parties.

If, as a result of the reductions required by Subsection 2(e)(i), the amounts previously paid to the Employee exceed the amount to which the Employee is entitled, the Employee will promptly return the excess amount to the Company.]

[OR]

                                    [(i)        To the extent
that any of the payments and benefits provided for in this Agreement or otherwise payable to the Employee in connection with a Change of Control (collectively, the "Payments") would result in a "parachute payment" within the meaning of Section 280G of the Internal
Revenue Code of 1986, as amended (the "Code"), the amount of such Payments shall be either:

                                    (A)       the full amount
of the Payments, or

                                    (B)       a reduced amount
which would result in no portion of the Payments being subject to the excise tax imposed pursuant to Section 4999 of the Code (the "Excise Tax"),

whichever of the foregoing amounts, taking into account the applicable federal, state and local income taxes and the Excise Tax, results in the receipt by the Employee, on an after-tax basis, of the greatest amount of benefit.  Unless the Company and the
Employee otherwise agree in writing, any determination required under this Subsection shall be made in writing by independent public accountants appointed by the Company and reasonably acceptable to the Employee (the "Accountants"), whose determination shall be
conclusive and binding upon the Employee and the Company for all purposes.  The Company shall bear all costs the Accountants may reasonably incur in connection with such determination, and the Company and the Employee shall furnish to the Accountants such
information and documents as the Accountants may reasonably request in order to make a determination under the Subsection.

                                    (ii)        If, as a
result of a reduction of Payments required by Subsection 2(e)(i), the amounts previously paid to the Employee exceed the amount to which the Employee in entitled, the Employee will promptly return the excess amount to the Company.]]

            3.         Definition of Terms.  The following terms referred to in this Agreement shall have the following meanings:

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                        (a)        Change of Control.  “Change of Control” shall mean the
occurrence of any of the following events:

                                    (i)         Any
“person’ (as such term is used in Sections 13(d) and 14(d) of the Securities Exchange Act of 1934, as amended) is or becomes the “beneficial owner” (as defined in Rule 13d-3 under said Act), directly or indirectly, of securities of the Company
representing more than fifty percent (50%) of the total combined voting power represented by the Company’s then outstanding voting securities; or

                                    (ii)        A merger
or consolidation of the Company with any other corporation or other business entity, other than a merger or consolidation which would result in the voting securities of the Company outstanding immediately prior thereto continuing to represent (either by remaining
outstanding or by being converted into voting securities of the surviving entity or parent thereof) more than fifty percent (50%) of the total combined voting power represented by the voting securities of the Company or such surviving or parent entity outstanding
immediately after such merger or consolidation; or

                                     (iii)       the complete
liquidation of the Company; or

                                     (iv)       the sale or
disposition by the Company of all or substantially all the Company’s assets.

                        (b)        Involuntary Termination.  “Involuntary Termination” shall
mean the Employee’s resignation within 60 days after any of the following:

                                     (i)        
Without the Employee’s express written consent, the assignment to the Employee of any significant duties or the significant reduction of the Employee’s duties, either of which is materially inconsistent with the Employee’s position with the Company
and responsibilities in effect immediately prior to such assignment, or the removal of the Employee from such position and responsibilities, which is not effected for death, Disability or for Cause;

                                     (ii)        Without
the Employee’s express written consent, any reduction in an amount greater than 5% in the base salary and/or or maximum incentive bonus (subject, however, to satisfaction of applicable goals with respect to the actual amount of incentive bonus earned) as in
effect immediately prior to such reduction, other than a reduction applied generally to all employees of the acquiring company;

                                     (iii)       Without the
Employee’s express written consent, any reduction in the kind or level of employee benefits to which the Employee is entitled immediately prior to such reduction, other than a reduction applied generally to all employees of the acquiring company;

                                    (iv)       Without the
Employee’s express written consent, the relocation of the Employee to a facility or a location more than 40 miles from the Employee’s then present location; or

                                     (v)        The
failure of the Company to obtain the assumption of the terms of this Agreement by any successors contemplated in Section 4 below;

5

provided, however, that the Employee’s resignation as a result of any of the foregoing conditions shall be a voluntary resignation, and not an Involuntary Termination, unless the Employee gives written notice of any such condition(s) to the Board and allows
the Company at least 10 days thereafter to correct such condition(s).

                        (c)        Cause.  For purposes of this Agreement, a termination for
“Cause” occurs if the Employee is terminated for any of the following reasons:

                                    (i)         The
Employee’s theft, dishonesty, misconduct or intentional falsification of any employment or Company records;

                                    (ii)        The
Employee’s intentional and improper disclosure or use of the Company’s confidential or proprietary information;

                                    (iii)       Any action by
the Employee that has a material detrimental effect on the Company’s reputation or business;

                                     (iv)       The
Employee’s failure or inability to perform any assigned duty reasonably expected of a person holding the Employee’s position after written notice from the Board to the Employee of, and a reasonable opportunity to cure, such failure or inability; or

                                    (v)        The
Employee’s conviction (including any plea of guilty or nolo contendere) for any criminal act that impairs the Employee’s ability to perform his duties for the Company.

                        (d)        Disability.  “Disability” shall mean that the Employee is
unable to perform one or more essential functions of his or her position as an employee of the Company as the result of his or her incapacity due to physical or mental impairment for 120 days (not necessarily consecutive) in any one year period.  Termination
resulting from Disability may only be effected after at least 30 days’ written notice by the Company of its intention to terminate the Employee’s employment.  In the event that the Employee resumes the performance of substantially all of his or her
duties as an employee of the Company before the termination of his employment becomes effective, the notice of intent to terminate shall automatically be deemed to have been revoked.

            4.         Severance.

                        No severance benefits shall be made under Section 2(a) unless and until the Employee shall, in consideration of such benefits,
execute a release of claims in a form substantially similar to the form attached hereto as Exhibit A; provided, however, that the release shall not in any way impact the right of Employee to be indemnified by the Company.

            5.         Successors.

                        (a)        Company’s Successors.  Any successor (or parent thereof) to the
Company (whether direct or indirect and whether by purchase, lease, merger, consolidation, liquidation or otherwise) or to all or substantially all of the Company’s business and/or assets shall assume the obligations under this Agreement and agree expressly to
perform the obligations under this Agreement in the same manner and to the same extent as the Company would be

6

 required to perform such obligations in the absence of a succession.  For all purposes under this Agreement, the term “Company” shall
include any successor (or parent thereof) to the Company’s business and/or assets which executes and delivers the assumption agreement described in this subsection (a) or which becomes bound by the terms of this Agreement by operation of law.

                        (b)        Employee’s Successors.  All rights of the Employee hereunder
shall inure to the benefit of, and be enforceable by, the Employee’s personal or legal representatives, executors, administrators, successors, heirs, distributees, devisees and legatees.  Employee shall have no right to assign any of his obligations or
duties under this Agreement to any other person or entity.

            6.         Notice.

                        (a)        General.  Notices and all other communications contemplated by this
Agreement shall be in writing and shall be deemed to have been duly given when personally delivered or when mailed by U.S. registered or certified mail, return receipt requested and postage prepaid.  In the case of the Employee, mailed notices shall be addressed
to him at the home address which he most recently communicated to the Company in writing.  In the case of the Company, mailed notices shall be addressed to its corporate headquarters, and all notices shall be directed to the attention of its General
Counsel.

                        (b)        Notice of Termination.  Any termination by the Company for Cause or by
the Employee as a result of a voluntary resignation or an Involuntary Termination shall be communicated by a notice of termination to the other party hereto given in accordance with Section 6 of this Agreement.  Such notice shall indicate the specific
termination provision in this Agreement relied upon, shall set forth in reasonable detail the facts and circumstances claimed to provide a basis for termination under the provision so indicated, and shall specify the termination date (which shall be not more than 15
days after the giving of such notice).

             7.         Miscellaneous Provisions.

                        (a)        No Duty to Mitigate.  The Employee shall not be required to mitigate
the amount of any payment contemplated by this Agreement (whether by seeking new employment or in any other manner), nor, except with respect to the Employment Benefits as described in Section 2(a)(iv), shall any such payment be reduced by any earnings
that the Employee may receive from any other source.

                        (b)        Waiver.  No provision of this Agreement shall be modified, waived or
discharged unless the modification, waiver or discharge is agreed to in writing and signed by the Employee and by an authorized officer of the Company (other than the Employee).  No waiver by either party of any breach of, or of compliance with, any condition or
provision of this Agreement by the other party shall be considered a waiver of any other condition or provision or of the same condition or provision at another time.

                        (c)        Choice of Law.  The validity, interpretation, construction and performance
of this Agreement shall be governed by the laws of the State of California.

7

                        (d)        Severability.  The invalidity or unenforceability of any provision or
provisions of this Agreement shall not affect the validity or enforceability of any other provision hereof, which shall remain in full force and effect.

                        (e)        Arbitration.  In the event of any dispute or claim relating to or
arising out of the Employee’s employment relationship with the Company, this Agreement, or the termination of the Employee’s employment with the Company for any reason (including, but not limited to, any claims of breach of contract, wrongful termination,
fraud or age, race, sex, national origin, disability or other discrimination or harassment), the Employee and the Company agree that all such disputes shall be fully, finally and exclusively resolved by binding arbitration conducted by the American Arbitration
Association in Santa Clara County, California.  The Employee and the Company hereby knowingly and willingly waive their respective rights to have any such disputes or claims tried to a judge or jury. Provided, however, that this arbitration provision shall not
apply to any disputes or claims relating to or arising out of the actual or alleged misuse or misappropriation of confidential information, including, but not limited to, either party’s trade secrets or proprietary information.

                        (f)         No Assignment of Benefits.  The rights of any person to payments
or benefits under this Agreement shall not be made subject to option or assignment, either by voluntary or involuntary assignment or by operation of law, including (without limitation) bankruptcy, garnishment, attachment or other creditor’s process, and any
action in violation of this subsection (f) shall be void.

                        (g)        Employment Taxes.  All payments made pursuant to this Agreement will
be subject to withholding of applicable income and employment taxes.

                        (h)        No Representations.  Each party acknowledges that it is not relying
and has not relied on any promise, representation or statement made by or on behalf of the other party that is not set forth in this Agreement.

                        (i)         Counterparts.  This Agreement may be executed in counterparts,
each of which shall be deemed an original, but all of which together will constitute one and the same instrument.

                        (j)         Prior Agreements.  This Agreement shall supersede all prior
arrangements whether written or oral, and understandings, regarding the subject matter of this Agreement.

                        (k)        Modification.  This Agreement may only be modified or amended by a
supplemental written agreement signed by Employee and the Company.

8

            In Witness Whereof, each of the parties has executed this Agreement, in the case of the Company by its duly authorized officer, as of the day and year first above written.

COMPANY                                                               
SangStat Medical Corporation

                                                                                   
By:                                                      

                                                                                   
Title:                                        
           

EMPLOYEE                                                               
By:                                                      

 

                                               

1  For executive officers, the range is one to two; for others, the range is one-half to one.

2  For executive officers, the range is one to two years; for others, the range is six months to one year.

3  For executive officers, the range is one to two years; for others, the range is one-half to one year.

4  Optional provision related to IRS Code Section 280G.

 

 

9

EXHIBIT A

GENERAL RELEASE OF CLAIMS

 

            1.         In exchange for the additional separation benefits offered to me by SangStat Medical Corporation (the
"Company") under the Change of Control Agreement entered into between the Company and myself on _________________, I, _________________, and my successors and assigns release and absolutely
discharge the Company and its shareholders, directors, employees, agents, attorneys, legal successors and assigns of and from any and all claims, actions and causes of action, whether now known or unknown, that I now have, or at any other time had, or shall or may
have against the Company based upon or arising out of any matter, cause, fact, thing, act or omission whatsoever occurring or existing at any time to and including the date hereof, including, but not limited to, any claims of wrongful termination, harassment, breach
of contract or national origin, race, age, sex or other discrimination under the Civil Rights Act of 1964, the Age Discrimination In Employment Act of 1967, the Americans With Disabilities Act, the California Fair Employment and Housing Act, or any other
applicable law.

             2.         I acknowledge that I have read section 1542 of the Civil Code of the State of California, which in its entirety states:

	
                            

	
A general release does not extend to claims which the creditor does not know or suspect to exist in his favor at the time of executing the release, which if known by him must have materially affected his settlement with the
debtor.

	
                            

 

I hereby waive any right or benefit which I have under section 1542 of the Civil Code of the State of California or any equivalent provision of any other state, to the fullest extent that I may lawfully waive such rights
pertaining to this Release of All Claims. Notwithstanding the above, I understand that I may retain whatever rights are otherwise preserved under law to file a charge or communicate with, or assist in any investigation or proceeding conducted by
or through a state or federal administrative agency.  However, in the event I bring any such claim or action I understand that I am not entitled to any actual relief or recovery therefrom, including recovery for any costs or attorney’s fees.

            3.         I acknowledge that I have carefully read and fully understand this release and I have not relied on any statement, written or oral, which is not set
forth in this document.

I UNDERSTAND THAT I AM ENTITLED TO CONSULT WITH AN ATTORNEY PRIOR TO SIGNING THIS RELEASE AND THAT I AM GIVING UP ANY LEGAL CLAIMS I HAVE AGAINST THE COMPANY BY SIGNING THIS RELEASE.  I ACKNOWLEDGE THAT I AM SIGNING THIS RELEASE KNOWINGLY, WILLINGLY AND
VOLUNTARILY IN EXCHANGE FOR THE SEPARATION BENEFITS DESCRIBED IN THE CHANGE OF CONTROL AGREEMENT. I FURTHER UNDERSTAND THAT I HAVE [21/45] DAYS TO CONSIDER THIS RELEASE, THAT I MAY REVOKE IT AT ANY TIME DURING THE EIGHT DAYS AFTER I SIGN IT, AND THAT IT SHALL
NOT BECOME EFFECTIVE UNTIL THAT EIGHT-DAY PERIOD HAS PASSED.

Dated:                          ,
200___                                  Name:                                                 

 

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