Document:

EX-10.8

 Exhibit 10.8 
 INSYS THERAPEUTICS, INC. 

EMPLOYMENT AGREEMENT 
 This Employment Agreement (“Agreement”) is entered into as of the 18th day of April, 2013 (the “Effective Date”), by and between Darryl S. Baker
(“Executive”) and Insys Therapeutics, Inc. (the “Company”). 

RECITALS 
 WHEREAS, Executive has been serving as an executive officer of the Company since on or about October 2012 and the Company desires to continue to employ Executive pursuant to the
terms, provisions and conditions set forth in this Agreement; and 
 WHEREAS, Executive desires to accept
and continue his employment on the terms, provisions and conditions set forth in this Agreement. 
 NOW,
THEREFORE, in consideration of the mutual promises and covenants contained herein, the Company and Executive agree as follows: 
 AGREEMENT 
 In consideration of the foregoing Recitals and
the mutual promises and covenants herein contained, and for other good and valuable consideration, the parties agree as follows: 
  

	 	1.	EMPLOYMENT BY THE COMPANY. 

1.1 Position. Subject to the terms set forth herein, the Company hereby employs Executive in the position of Chief Financial
Officer and Executive hereby accepts such employment. During Executive’s employment by the Company, Executive shall devote Executive’s full business energies, interest, abilities and productive time to the proper and efficient performance
of Executive’s duties under this Agreement. 
 1.2 Duties and Location. Executive shall have the title of Chief
Financial Officer and shall report to the Company’s Chief Executive Officer (“CEO”). Executive shall do and perform all services, acts or things necessary or advisable which are normally associated with the position of
Chief Financial Officer, as required by the CEO. Executive shall work at the Company’s facility in Chandler, Arizona, provided that the Company may from time to time require Executive to travel temporarily to other locations in connection with
the Company’s business. 

  
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 1.3 Policies and Procedures. The employment relationship between the parties shall be
governed by this Agreement and by the policies and practices established by the Company and/or the Company’s Board of Directors (the “Board”). In the event that the terms of this Agreement differ from or are in conflict
with the Company’s policies or practices, this Agreement shall control. 
 1.4 Exclusive Employment. Except with the
prior written consent of the Board, Executive will not during employment with the Company undertake or engage in any other employment, occupation or business enterprise, other than ones in which Executive is a passive investor. 

1.5 Agreement not to Participate in Company’s Competitors. During Executive’s employment with the Company, Executive
agrees not to acquire, assume or participate in, directly or indirectly, any position, investment or interest known by Executive to be adverse or antagonistic to the Company, its business, or prospects, financial or otherwise, or in any company,
person, or entity that is, directly or indirectly, in competition with the business of the Company or any of its Affiliates (as defined below). Ownership by Executive, in professionally managed funds over which the Executive does not have control or
discretion in investment decisions, or as a passive investment, of less than two percent (2%) of the outstanding shares of capital stock of any corporation with one or more classes of its capital stock listed on a national securities exchange
or publicly traded on a national securities exchange or in the over-the-counter market shall not constitute a breach of this Section. For purposes of this Agreement, “Affiliate,” means, with respect to any specific entity,
any other entity that, directly or indirectly, through one or more intermediaries, controls, is controlled by or is under common control with such specified entity. 
 1.6 Covenant not to Compete. During the term of this Agreement and for a period of one (1) year thereafter, Executive shall not engage in competition with the Company and/or any of its
Affiliates, either directly or indirectly, in any manner or capacity, in any phase of the business of developing, manufacturing and marketing of (a) products incorporating tetrahydrocannabinol (THC) or derivatives or synthetic versions thereof,
(b) spray technologies for use in drug delivery of pain medication, or (c) any new molecules which were in development at the time of departure, except with the prior written consent of the Board. 

 

	 	2.	AT-WILL EMPLOYMENT. 

 Executive’s employment relationship with the Company is, and shall all times remain, at will. This means that either Executive or the Company may terminate the employment relationship at any time,
for any reason or for no reason, with or without cause or advance notice. 
  

	 	3.	COMPENSATION AND BENEFITS. 

 3.1 Salary. The Company shall pay Executive a base salary at the annualized rate of One Hundred and Seventy Thousand Dollars ($170,000.00) (the “Base Salary”), less payroll
deductions and all required withholdings, payable in regular periodic payments in accordance with the Company’s normal payroll practices. Notwithstanding the foregoing, the Executive’s Base Salary shall be increased to the annualized rate
of Two Hundred and Ten 

  
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Thousand Dollars ($210,000) upon the earlier of (i) the Company attaining profitability, as determined by the Board and (ii) the closing of the initial public offering for the
Company’s common stock, and in each of (i) or (ii), provided that Executive continues to perform his duties under this Agreement to the satisfaction of the Board. The Base Salary shall be prorated for any partial year of employment on the
basis of a 365-day fiscal year. The Base Salary may be adjusted from time to time in the Company’s discretion. 
 3.2
Performance Bonus. Executive will be eligible to participate in any officer incentive program of the Company adopted by the Board and/or the compensation committee of the Board that provides for the payment of annual performance-based cash
bonuses to the Company’s executive officers. Any cash bonus earned by Executive pursuant to any such program will be subject to standard payroll deductions and applicable tax withholdings. In order to earn and receive any such cash bonus,
Executive must remain employed by the Company as an employee in good standing through the end of the applicable calendar year and the payout date for the bonus. 
 3.3 Standard Company Benefits. Executive shall, in accordance with Company policy and the terms of the applicable plan documents, be eligible to participate in benefits under any benefit plan or
arrangement that may be in effect from time to time and made available to the Company’s employees. 
 3.4 Expense
Reimbursements. The Company will reimburse Executive for all reasonable business expenses Executive incurs in conducting his duties hereunder, pursuant to the Company’s usual expense reimbursement policies. 

 

	 	4.	PROPRIETARY INFORMATION OBLIGATIONS. 

As a condition of employment Executive agrees to execute and abide by the Company’s Proprietary Information and Inventions Agreement
(“PIIA”). Executive acknowledges and agrees that his obligations under the PIIA are retroactively effective to and including his first day of employment with the Company. 

 

	 	5.	COMPENSATION UPON TERMINATION. 

5.1 Termination Without Cause or Resignation For Good Reason. If the Company terminates Executive’s employment without Cause
(as defined below and other than as a result of Executive’s death or disability), or if Executive resigns his employment for Good Reason (as defined below), then the Company shall pay Executive any base salary and accrued and unused vacation
benefits earned through the date of termination, at the rate in effect at the time of termination, less standard deductions and withholdings. In addition, if Executive furnishes to the Company an executed waiver and release of claims in a form to be
provided by the Company (the “Release”) within the time period specified therein, but in no event later than forty-five (45) days following Executive’s termination, and if Executive allows such Release to become
effective in accordance with its terms, then Executive shall be entitled to: (1) severance in the form of continuation of Executive’s salary (at the Base Salary rate in effect at the time of termination) for a period of twelve
(12) months following the termination date; (2) an additional severance payment 

  
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equal to Executive’s target bonus for the year in which the qualifying termination or resignation is effective, pro rated for the number of days Executive was employed by the Company in such
year; and (3) accelerated vesting of any unvested shares subject to any outstanding stock options and/or other equity awards, such that, on the effective date of the Release, the Executive shall be vested in one hundred percent (100%) of
the shares subject to such options and/or awards. The severance payments will be subject to standard payroll deductions and withholdings and will be made on the Company’s regular payroll cycle, provided, however, that any payments otherwise
scheduled to be made prior to the effective date of the Release shall accrue and be paid in a lump sum on the first payroll period that follows such effective date. 
 5.2 Termination Other Than Without Cause or Resignation Other Than For Good Reason. If Executive’s employment with the Company ends for any reason or
in any circumstance other than those specified in Section 5.1 above, including but not limited to a termination by the Company for Cause or a resignation by Executive without Good Reason, the Company shall pay Executive any base salary
and accrued and unused vacation benefits earned through the date of termination, at the rate in effect at the time of termination, less standard deductions and withholdings. The Company shall thereafter have no further obligations to Executive under
this Agreement, except as otherwise provided by law. 
  

	 	6.	DEFINITIONS. 

 For purposes of this Agreement, the following terms shall have the following meanings: 
 6.1 Cause. “Cause” shall mean the occurrence of any of the following, as determined by the Board: (i) Executive’s conviction of any felony or any crime involving
fraud or dishonesty; (ii) Executive’s participation (whether by affirmative act or omission) in a fraud, act of dishonesty or other act of misconduct against the Company and/or its affiliates; (iii) conduct by Executive which, based
upon a good faith and reasonable factual investigation by the Board, demonstrates Executive’s gross unfitness to serve; (iv) Executive’s violation of any statutory or fiduciary duty, or duty of loyalty, owed to the Company;
(v) Executive’s breach of any material term of any material contract between such Executive and the Company, after written notice to Executive and an opportunity of at least thirty (30) days to cure; (vi) Executive’s
repeated violation of any material Company policy, after written notice to Executive and an opportunity of at least thirty (30) days to cure; and/or (vii) Executive’s repeated failure to adequately perform his job duties, after
written notice to Executive and an opportunity of at least thirty (30) days to cure. Whether a termination is for Cause shall be decided by the Board in its sole and exclusive judgment and discretion. 

6.2 Good Reason. “Good Reason” for Executive to terminate his employment hereunder shall mean the
occurrence of any of the following events without Executive’s consent: (i) a material reduction by the Company of Executive’s Base Salary as initially set forth herein or as the same may be increased from time to time, provided,
however, that if such reduction occurs in connection with a Company-wide decrease in Executive compensation, such reduction shall not constitute Good Reason for Executive to terminate his employment; (ii) a material breach of this Agreement by
the Company; (iii) a material reduction that amounts to an adverse change in Executive’s duties, authority, or responsibilities relative to Executive’s duties, 

  
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authority, or responsibilities in effect immediately prior to such reduction; or (iv) a relocation of Executive’s principal place of employment to a location outside of the greater
Phoenix metropolitan area and that constitutes a material change in the geographic location at which Executive must perform services under this Agreement. 
 Provided, however, that, any such termination by Executive shall only be deemed for Good Reason pursuant to this definition if: (1) Executive gives the Company written notice of his
intent to terminate for Good Reason within thirty (30) days following the first occurrence of the condition(s) that he believes constitute(s) Good Reason, which notice shall describe such condition(s); (2) the Company fails to remedy such
condition(s) within thirty (30) days following receipt of the written notice (the “Cure Period”); and (3) Executive voluntarily terminates his employment within thirty (30) days following the end of the Cure
Period. 
  

	 	7.	GENERAL PROVISIONS. 

 7.1 Representations and Warranties. Executive represents and warrants that Executive is not restricted or prohibited, contractually or otherwise, from entering into and performing each of the terms
and covenants contained in this Agreement, and that Executive’s execution and performance of this Agreement will not violate or breach any other agreements between the Executive and any other person or entity. 

7.2 Survival. Sections 4, 5, 6 and 7 of this Agreement will survive the termination of this Agreement. 

7.3 Miscellaneous. This Agreement, along with the PIIA, constitutes the complete, final and exclusive embodiment of the entire
agreement between Executive and the Company with regard to its subject matter. It is entered into without reliance on any promise or representation, written or oral, other than those expressly contained herein, and it supersedes any other such
promises, warranties or representations. This Agreement may not be modified or amended except in a writing signed by both Executive and a duly authorized officer of the Company. This Agreement will bind the heirs, personal representatives,
successors and assigns of both Executive and the Company, and inure to the benefit of both Executive and the Company, and to his and its heirs, successors and assigns. If any provision of this Agreement is determined to be invalid or unenforceable,
in whole or in part, this determination will not affect any other provision of this Agreement and the provision in question will be modified so as to be rendered enforceable. This Agreement will be deemed to have been entered into and will be
construed and enforced in accordance with the laws of the State of Arizona as applied to contracts made and to be performed entirely within Arizona. Any ambiguity in this Agreement shall not be construed against either party as the drafter. Any
waiver of a breach of this Agreement shall be in writing and shall not be deemed to be a waiver of any successive breach. This Agreement may be executed in counterparts and facsimile signatures will suffice as original signatures. 

7.4 Section 409A. The severance benefits and other payments payable under this Agreement are intended to qualify for an
exemption from application of Section 409A of the Internal Revenue Code of 1986, as amended and the Treasury Regulations and other guidance promulgated thereunder (the “Code”) and any state law of similar effect
(collectively “Section  

  
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409A”) or comply with its requirements to the extent necessary to avoid adverse personal tax consequences under Section 409A, and any ambiguities herein shall be
interpreted accordingly. Notwithstanding anything to the contrary herein, the following provisions apply to the extent benefits provided herein are subject to Section 409A. Severance benefits shall not commence until Executive has a
“separation from service” for purposes of Section 409A. Each installment of severance benefits is a separate “payment” for purposes of Treas. Reg. Section 1.409A-2(b)(2)(i), and the severance benefits are intended to
satisfy the exemptions from application of Section 409A provided under Treasury Regulations Sections 1.409A-1(b)(4), 1.409A-1(b)(5) and 1.409A-1(b)(9). However, if such exemptions are not available and Executive is, upon separation from
service, a “specified employee” for purposes of Section 409A, then, solely to the extent necessary to avoid adverse personal tax consequences under Section 409A, the timing of the severance benefits payments shall be delayed
until the earlier of (i) six (6) months and one day after Executive’s separation from service, or (ii) Executive’s death. 
 Executive shall receive severance benefits only if Executive executes and returns to the Company, within the applicable time period set forth therein but in no event more than forty-five (45) days
following the date of separation from service, the Release, and permits such Release to become effective in accordance with its terms (such latest permitted date, the “Release Deadline Date”). If the severance
benefits are not covered by one or more exemptions from the application of Section 409A and the Release could become effective in the calendar year following the calendar year in which Executive separates from service, the Release will not be
deemed effective any earlier than the Release Deadline Date. None of the severance benefits will be paid or otherwise delivered prior to the effective date of the Release. Except to the minimum extent that payments must be delayed because Executive
is a “specified employee” or until the effectiveness of the Release, all amounts will be paid as soon as practicable in accordance with the Company’s normal payroll practices. 

[SIGNATURE PAGE TO FOLLOW] 

  
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 IN WITNESS WHEREOF, the
parties have executed this Employment Agreement as of the day and year first written above. 
  

			
	INSYS THERAPEUTICS, INC.
		
	By:	 	 /s/ Michael Babich

	Name:	 	Michael Babich
	Title:	 	President and Chief Executive Officer

 Accepted and agreed: 
  

	
	 /s/ Darryl S. Baker

	Darryl S. Baker

  
 7EX-10.1

 Exhibit 10.1 
 SEVERANCE AGREEMENT AND GENERAL RELEASE 
 This
Severance Agreement and General Release (the “Agreement”) is made and entered into by and between Nanosphere, Inc. (the “Company”) and Tim Patno (“Employee”) (collectively, “the Parties”). 

This Agreement sets forth the terms and conditions pursuant to which the Employee is separating from employment with the
Company. 
 Separation of Employment. In consideration of the foregoing, and for other good and valuable
consideration, the sufficiency of which is hereby acknowledged, the Employee shall separate from employment with the Company effective April 22, 2013 (the “Separation Date”). The period of time between the date of this Agreement and
the Separation Date is referred to herein as the “Remaining Employment Term.” 
 Compensation
During Remaining Employment Term. During the Remaining Employment Term, Employee shall continue to receive his base salary (the “Base Salary”) at the rate in effect on the date of this Agreement, and shall continue to participate in
all employee benefit plans in accordance with their terms. As soon as practical following the Separation Date, Employee shall receive any unpaid Base Salary accrued through the Separation Date, and payment for earned but unused vacation time in
accordance with the Company’s established payroll practices. Effective as of the Notice Date, Employee is no longer authorized to incur any reimbursable business expenses without the prior written consent of the Chief Executive Officer of the
Company. Employee acknowledges that he is not entitled to any additional compensation from the Company with respect to his employment, except as otherwise provided herein, including any annual or other performance bonuses. 

Severance Pay. Provided that Employee (i) remains in employment through the Separation Date,
(ii) complies with all of his obligations under this Agreement, including without limitation those set forth in Section 4, (iii) if this Agreement is signed by Employee prior to the Separation Date, executes and delivers to the
Company the Supplemental Release attached hereto as Exhibit A on a date that is not earlier than the Separation Date and not later than 21 days after the Separation Date, and (iv) does not revoke either this Agreement or the Supplemental
Release, if applicable, then the Company will pay to Employee as severance pay (the “Severance Pay”) on each regular payroll date commencing with the first payroll date following the Separation Date and ending on the last payroll date that
occurs on or before December 31, 2013, an amount equal the amount of Base Salary (prior to any deductions) that the Employee would have received if he were still employed by the Company. Each installment of Severance Pay, if earned, shall be
paid on the applicable payroll date (or, if later, the date on which the Employee’s right to revoke this Agreement or the Supplemental Release expires), shall be subject to all applicable tax withholding, and shall constitute a separate
“payment” for purposes of §409A of the Internal Revenue Code. 

 Obligations of Employee. During the period commencing with the date
of this Agreement and ending on December 31, 2013 (or such later date as may be provided below), Employee shall: 
  

	 	 (a)
	 Employee shall download and transfer to the Company of all technical and relevant files both paper and electronic relating to all Company matters
within Employee’s control 

  

	 	 (b)
	 Employee shall furnish reports as require by the Company providing full disclosure of all projects currently in process in all of Employee’s
areas of responsibility. 

  

	 	 (c)
	 Employee shall fully cooperate in transitioning all of Employee’s responsibilities to persons designated by the Company, including but not
limited to any open aspects of FDA or related documentation related to submissions or inspection. 

  

	 	 (d)
	 Until the second anniversary of the Separation Date, Employee shall not solicit, aid or induce any person who, at any time during Employee’s
employment by the Company, was an employee, representative or agent of the Company or any of its subsidiaries to leave such employment or retention or to accept employment with or render services to or with any other person, firm, corporation or
other entity unaffiliated with the Company, or hire or retain any such employee, representative or agent, or take any action to materially assist or aid any other person, firm, corporation or other entity in identifying, hiring or soliciting any
such employee, representative or agent. 

  

	 	 (e)
	 At all times during the Remaining Employment Term and thereafter, Employee shall not make negative comments or otherwise disparage the Company or
its officers, directors, employees, shareholders, members, agents or products; provided that the foregoing shall not be violated by truthful statements in response to legal process, required governmental testimony or filings, or administrative or
arbitral proceedings (including, without limitation, depositions in connection with such proceedings). 

  

	 	 (f)
	 Comply with all remaining provisions of this Agreement, including without limitation those contained in Sections 11 (relating to return of property)
and 12 (relating to unauthorized use of proprietary information). 

 Employee’s right to the Severance
Pay is expressly conditioned upon Employee’s continued compliance with each of the obligations set forth above. Prior to each payroll date through December 31, 2013, Employee’s continued compliance with such obligations shall be
reviewed by the Company’s Chief Executive Officer, in consultation with the Company’s Chief Financial Officer and Human Resources Manager, and no 

 
Severance Pay shall be paid on any payroll date unless the Chief Executive Officer has determined that Employee is in compliance with such obligations. If at any time the Company determines that
the Employee is not in compliance with these obligations, Employee’s right to the Severance Pay shall immediately terminate, and Employee may be required to repay any Severance Pay he has previously received, except that the Company may permit
the Employee to retain $500.00 of the Severance Pay which shall be consideration for Employee’s release of claims and covenant not to sue as set forth below. 

Group Health Insurance Benefits. Employee will not earn any benefits under, and will not participate in, any
Company benefit plans or programs following the Separation Date. Notwithstanding the foregoing, Employee shall have whatever rights may exist under COBRA to continue to participate in the Company’s group health insurance plan following the
Termination Date, provided he elects to continue such coverage at his expense in a timely manner and complies with all established terms and conditions for such continuation of coverage. 

Equity. Vesting and exercisability of all outstanding stock options, shares of restricted stock, and other equity
grants to Employee shall be governed by the terms of the respective equity grant agreement or plan. 
 No
Further Obligations. Except for the obligations expressly set forth in this Agreement, the Company shall make no further payments or contributions on behalf of the Employee or Employee’s family members, whether for salary, vacation, sick
days, life insurance, long term disability insurance or any other form of insurance or for any other compensation or benefits following the Separation Date. 
 General Release. 
 (a) General Release of Employee
Claims. For and in consideration of the Severance Pay, and the other covenants of the Company made herein, Employee agrees that by executing this Agreement Employee does hereby, on behalf of Employee, Employee’s heirs, executors,
administrators, representatives, successors and assigns, irrevocably and unconditionally release and forever discharge the Company, all affiliated or related entities, successors, predecessors, assigns or representatives, and any present and former
officers, directors, trustees, board members, employees, agents, attorneys, and insurers, and all persons acting for, by, through, under or in concert with any of them (hereinafter “Released Parties”), of and from any and all claims,
demands, liabilities, actions, causes of action, rights, obligations, suits, debts, accounts, claims for attorneys’ fees, interest, expenses and costs, damages, judgments, and executions of any nature whatsoever (collectively,
“Claims”), which Employee, Employee’s heirs, executors, administrators, representatives, successors, or assigns, had, now have, or may hereafter have, from the beginning of time to the date hereof, against any of the Released Parties,
whether based on federal or state statute, common law, rule or regulation, whether in law or in equity, contract or tort, whether liquidated or unliquidated, whether known or unknown, related to Employee’s employment with the Company and/or the
termination therefrom. This general release includes but is not limited to Claims arising out of or in 

 
connection with: (i) any allegation that the Company wrongfully or unlawfully terminated, discharged, or laid off Employee; (ii) any allegation of violation of the Age Discrimination in
Employment Act, the Americans with Disabilities Act, Title VII of the Civil Rights Act of 1964, as amended, the Civil Rights Acts of 1866, 1871, and 1991, including Sections 1981 and 1983 of the Civil Rights Act, the Worker’s Adjustment and
Retraining Notification Act, the National Labor Relations Act, the Rehabilitation Act of 1973, the Corporate and Criminal Fraud Accountability Act of 2002, Title VIII of the Sarbanes-Oxley Act of 2002, the Illinois Human Rights Act, and the Illinois
Whistleblower Act; (iii) any allegation of defamation, intentional or negligent infliction of emotional distress, workplace harassment, discrimination, or retaliation, invasion of privacy, violation of public policy, negligence, or any other
tort; (iv) any allegation of a breach of any contract of employment, express or implied, or of a violation of any Company policy or procedure, the provisions of the Constitution of the United States or of any other state, and/or any other law,
rule, regulation or ordinance pertaining to employment and/or the termination of employment; and/or (v) any other statutory or common law cause of action. 
 (b) Nature of Release. The release contained in this Section 8 is a GENERAL RELEASE and any reference to specific Claims arising out of Employee’s employment or its termination is not
intended to limit this release of Claims. Employee acknowledges and understands that he may later discover facts in addition to or different from those he currently knows or believes to be true regarding rights or Claims covered by this release. In
signing this Agreement, Employee nonetheless intends to give up all rights and Claims covered by the release, whether known or unknown, suspected or unsuspected. 

(c) Exclusions from Employee Release. Excluded from the release above are rights and Claims which cannot be waived
by law, including Claims for workers’ compensation, unemployment compensation, accrued and vested retirement benefits, and Claims arising after the date on which this Agreement is signed. Also excluded from the release are Employee’s
rights to file a charge with an administrative agency (such as the U.S. Equal Employment Opportunity Commission) or participate in an agency investigation. Employee is, however, waiving all rights to recover money or other individual relief in
connection with any administrative charge filed by Employee or any other person or entity. 
 Covenant Not To
Sue. A “covenant not to sue” is a legal term which means the Employee and the Company each promises not to file a lawsuit in court. It is different from the release contained in Section 8 above. Besides releasing Claims covered by
that release, Employee agrees never to sue any of the Released Parties in any forum for any reason covered by the release. Notwithstanding this Covenant Not To Sue, the Employee may bring a claim against the Company to enforce this Agreement or to
challenge its validity under the Age Discrimination in Employment Act. If Employee sues a Released Party in violation of this Agreement, Employee: (i) shall be liable to the Released Party for its reasonable attorneys’ fees and other
litigation costs incurred in defending against such a suit; or alternatively (ii) the Company can require the Employee to return all but $500.00 of the Severance paid to him under this Agreement. In that event, the Company shall be excused from
any remaining obligations that exist solely because of this Agreement. 

 No Admission. Employee understands and agrees that the payment of
monies and other consideration set forth in this Agreement does not constitute an admission of liability or violation of any applicable law, regulation, or agreement, and in fact the Released Parties expressly deny any such liability or violation.

 Return of Property. Employee agrees, to the extent Employee has previously failed to do so, to return
immediately all documents, reports, files, financial information, customer lists, keys, credit cards, keycards, employee identification cards, pagers, remote computer access tokens, computers, programs, software and discs, including, but not by way
of limitation, those programs, software, and discs generated during Employee’s employment with the Company, and all other items which are the property of the Company, or contain information which belongs to the Company or any of the Released
Parties. Employee agrees that Employee will not retain any copies, duplicates, reproductions or excerpts of any of the foregoing. 
 Proprietary Information. Employee hereby agrees that Employee shall not use for Employee’s own benefit or for the benefit of any third party, nor shall Employee disclose to any third party any
proprietary, non-public, or otherwise confidential information of or regarding the Company or its operations, products, manufacturing processes or procedures, services, financial information, data, or reports, pricing, customers, prospective
customers, suppliers, or employees, computer programs, marketing information and procedures, including but not limited to sales, pricing policies, operational methods, business plans and plans for future development, and other business information
which is not readily available to the public. 
 Company’s Right to Interpret. The Company shall
have the sole authority and discretion to interpret the terms of this Agreement, and any determination made in good faith by the Company related to this Agreement, including without limitation whether the Employee has breached any his obligations
hereunder, shall be final and binding on all parties to the maximum extent permitted by applicable law. 
 No
Reemployment. Employee agrees to waive any employment rights with any of the Released Parties that Employee might otherwise have now or in the future, including reinstatement or reemployment. Employee agrees that Employee will not apply for
employment with the Company or with any of its divisions, subsidiaries, or successors, at any time in the future. 
 Prior Charges or Complaints. Employee represents that if Employee has filed, with any administrative agency or court, any complaint or charge against the Company or any of the Released Parties
involving any events up to and including the date of this Agreement, Employee has disclosed such complaint or charge, in writing, to the Company’s Human Resources Department. 

 Non-Assignment. Employee represents that Employee has not assigned or
otherwise transferred to any party any claim that is being released pursuant to this Agreement. 

Outstanding Expenses and Other Advances. Employee represents that Employee has submitted all outstanding expenses
and has cleared all advances. Employee acknowledges that any advances that are unaccounted for shall be offset against the Severance Pay described above. 
 No Other Promises. Employee represents that in executing this Agreement, no promise or inducement has been made to Employee except as set forth in this Agreement and that Employee is entering into
this Agreement without any threat or coercion and without reliance on any statement or representation, written or oral, made by any person representing the Company, except as expressly set forth in this Agreement. 

Entire Agreement. This Agreement constitutes the entire and complete agreement between the parties. No other
promises or agreements, either express or implied, shall be binding unless in writing and signed by all parties. 
 Severability. Each of the terms of this Agreement is deemed severable in whole or in part and if any term or provision, or the application thereof, in any circumstance should be illegal, invalid,
or unenforceable, the remaining terms and provisions shall not be affected thereby and shall remain in full force and effect. 
 Governing Law. Except to the extent preempted by federal law, this Agreement is made and entered into in the State of Illinois and in all respects the rights and obligations of the parties
shall be interpreted, enforced, and governed in accordance with the laws of the State of Illinois which are applicable to contracts made and to be performed in that state and without regard to the principles of conflict of laws. Any and all
lawsuits, legal actions or proceedings against either party arising out of this Agreement or Employee’s employment with the Company shall be brought in any court of appropriate jurisdiction sitting in the City of Chicago, Illinois and each
party hereby submits to and accepts the exclusive jurisdiction of such courts for the purpose of such suit, legal action or proceeding. Each party hereby irrevocably waives any objection it may now have or hereafter have to this choice of venue of
any suit, legal action or proceeding in any such court and further waives any claim that any suit, legal action or proceeding brought in any such court has been brought in an inappropriate forum. 

Successors and Assigns. This Agreement shall be binding on and inure to the benefit of the parties and their legal
representatives, transferees, successors and assigns. 
 Employee Acknowledgement. Employee acknowledges
that Employee has entered into this Agreement freely and voluntarily, and that Employee has had adequate time to read this Agreement and to consult with Employee’s attorney on its terms and to reflect upon the consequences of Employee’s
execution thereof. Employee acknowledges that the Company offered Employee twenty-one (21) days within which to consider this Agreement, and that the Company advises Employee to consult with an

 
attorney prior to executing this Agreement. The Parties agree that the twenty-one day period started on the date that Employee first received this Agreement from the Company, and that any changes
made to the Agreement since that date, whether material or immaterial, have not restarted the running of the twenty-one day period. 
 Within seven (7) days following Employee’s execution of the Agreement, Employee may revoke his release of claims contained in Section 8 and his covenant not to sue contained in
Section 9, and this Agreement shall not become effective or enforceable until this seven-day revocation period has expired. Any such revocation must be in writing and either delivered by hand within such seven-day period, or deposited in the
United States mail, with proper first class postage pre-paid, and postmarked by the end of the seven-day period, and in either case addressed to Michael K. McGarrity, President and Chief Executive Officer at Nanosphere, Inc., 4088 Commercial Avenue,
Northbrook, Illinois, 60062. In the event Employee exercises Employee’s right of revocation, Employee will not be entitled to receive the Severance Pay, and will not be bound by either his release of claims contained in Section 8 or his
covenant not to sue contained in Section 9, but the remaining provisions of this Agreement shall remain in full force and effect. 
 [Signatures on Following Page] 

							
	 NANOSPHERE, INC.
	 		 	 [EMPLOYEE NAME]

				
	 By:
	 	 /s/ Michael K. McGarrity
	 		 	 /s/ Tim Patno

		 	 Michael K. McGarrity
	 		 	
		 	 President and CEO
	 		 	 Dated: April 23, 2013

 Dated: April 22, 2013 

 EXHIBIT A 
 INSTRUCTIONS: This Supplemental Release is required only if the Severance Agreement and General Release (the “Release”) between Nanosphere, Inc. (the “Company”) and
                    (the “Employee”) is signed prior to the “Separation Date”, as defined therein. If the Release is signed prior
to the Separation Date, then, in order to receive the Severance Pay described in the Release, the Employee must sign this Supplemental Release and return it to the Company not before the Separation Date and not later than twenty-one (21) days
after the Separation Date. This Supplemental Release must be dated during such 21 day period, and either delivered by hand within such 21-day period, or deposited in the United States mail, with proper first class postage pre-paid, and postmarked by
the end of the 21-day period, and in either case addressed to Michael K. McGarrity, President and Chief Executive Officer at Nanosphere, Inc., 4088 Commercial Avenue, Northbrook, Illinois, 60062. 

The Employee may revoke this Supplemental Release at any time within seven days after it is signed and delivered to the Company. Any such
revocation must be in writing and either delivered by hand within such seven-day period, or deposited in the United States mail, with proper first class postage pre-paid, and postmarked by the end of the seven-day period, and in either case
addressed to the same address stated above. In the event Employee exercises Employee’s right of revocation, this Supplemental Release will be null and void, and Employee will not be entitled to receive the Severance Pay, but the remaining
provisions of the Release shall remain in full force and effect. 
 The Employee is hereby advised that he has a period of not
less than twenty-one (21) days to consider whether to sign this Supplemental Release, and is advised to consult an attorney with respect to this Supplemental Release. 
 SUPPLEMENTAL RELEASE 
 In consideration of his right to
receive the Severance Pay described in Section 3 of the Severance Agreement and General Release (the “Release”) between himself and Nanosphere, Inc. (the “Company”), and the other covenants of the Company contained in the
Release,                     (“Employee”) hereby reaffirms his release of Claims contained in Section 8 of the Release and his
covenant not to sue with respect to such Claims contained in Section 9 of the Release, and agrees that such release and covenant not to sue shall also apply to any Claims (as defined in Section 8 of the Release) that did not exist on the
date the Release was signed, but that exist on the date this Supplemental Release is signed. 
 Employee
acknowledges that he has been given twenty-one (21) days to consider whether to sign this Supplemental Release and advised to consult an attorney before deciding whether to sign, that he has the right to revoke this Supplemental Release within
seven (7) days after signing it in accordance with the “Instructions” above, and that he will have no right to receive the Severance until such seven-day revocation period has expired. 

In all other respects, the Release shall remain in full force and effect. 

 

	
	  
	 [NAME]

	 Dated:                     , 2013

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