Document:

EXHIBIT 10.1

THE BANK OF NEW YORK
New York's First Bank  o  Founded 1784 by Alexander Hamilton

February 20, 2000

Mr. Robert P. Heller, Vice President &
Chief Financial Officer
National Home Health Care Corp.
700 White Plains Road, Suite 275
Scarsdale, New York  10583

Dear Bob:

This letter  confirms that The Bank of New York (the "Bank")  holds  available a
$2,000,000  secured  advised  line of credit to National  Home Health Care Corp.
(the "Borrower").

Advances  under the line of credit shall be payable on demand and bear  interest
at a rate per annum equal to the alternate base  commercial  lending rate of the
Bank as publicly  announced  to be in effect  from time to time (the  "Alternate
Base  Rate"),  such rate to change on the  effective  date of any  change in the
Alternate Base Rate.

         "Alternate  Base Rate" shall mean,  for any day, a rate per annum equal
         to the  higher of (i) the Prime Rate in effect on such day and (ii) the
         Federal Funds Rate in effect on such day plus 1/2 of 1%.

For purposes of this definition:

         "Prime Rate" shall mean, for any day, the weighted average of the rates
         on overnight  Federal  funds  transactions  with members of the Federal
         Reserve System arranged by Federal funds brokers, as published for such
         day (or if such  day is not a  business  day,  for the  next  preceding
         business  day,  the  average  of  quotations   for  such  day  on  such
         transactions  received by the Bank from three  Federal funds brokers of
         recognized standing selected by the Bank.

All advances and all principal  payments hereunder shall be endorsed by the Bank
on the sheet  attached to the  Promissory  Grid Note and shall be secured by all
assets of the Borrower pursuant to a security agreement. The Borrower authorizes
the Bank to accept telephonic instructions from a duly authorized representative
of the Borrower,  as indicated by the latest  Corporate  Resolution on file with
the Bank, to make an advance or receive a repayment hereunder and to endorse the
sheet  attached to this  Promissory  Grid Note  accordingly.  All advances  made
hereunder shall be credited to the Borrower's deposit account referred to above,
which credits shall be confirmed to the Borrower by standard advice of credit.

<PAGE>

The Borrower agrees that the actual crediting of the sum of money so borrowed to
the Borrower's a deposit account shall constitute  conclusive  evidence that the
advance  was made,  and the  failure  of the Bank to  endorse  the amount of any
advance on the sheet  attached  to this note or to forward  to the  Borrower  an
advice of credit shall not affect the  obligation  of the Borrower to repay such
advance.

In  addition,  all  advances  under  the line of  credit  shall be  jointly  and
severally  guaranteed by Health  Acquisition  Corp., New England Home Care, Inc.
and Accredited  Health  Services,  Inc. Each  guarantee  shall be secured by all
assets of the respective  guarantors pursuant to a security agreement.  The form
of note,  security  agreement and guarantee to be furnished to the Bank shall be
in form and substance acceptable to the Bank and its counsel.

Advances  under the line of credit are subject to the Bank's  satisfaction  with
(i) the  specific  purpose and  expected  time and source of  repayment  of each
advance,  and (ii)  the  Borrower's  and the  guarantors'  financial  condition,
business  prospects and  operations  at the time of each  advance.  As you know,
lines of credit may be canceled  by either  party at any time,  however,  unless
canceled  earlier,  the line of credit shall be held available until January 31,
2001.

Additionally, all outstanding advances under the line of credit shall be reduced
to zero for a period of 30  consecutive  days  during  each  twelve  (12)  month
calendar period in which the line of credit is held available.

Sincerely,

THE BANK OF NEW YORK

/s/ Vito Caraccio
-----------------
Vito Caraccio
Vice PresidentEXHIBIT 10.2

THE BANK OF NEW YORK
New York's First Bank  o  Founded 1784 by Alexander Hamilton

February 20, 2000

Mr. Robert P. Heller, Vice President &
Chief Financial Officer
National Home Health Care Corp.
700 White Plains Road, Suite 275
Scarsdale, New York  10583

Dear Bob:

This letter  confirms that The Bank of New York (the "Bank")  holds  available a
$2,000,000  secured  advised line of credit to New England Home Care,  Inc. (the
"Borrower").

Advances  under the line of credit shall be payable on demand and bear  interest
at a rate per annum equal to the alternate base  commercial  lending rate of the
Bank as publicly  announced  to be in effect  from time to time (the  "Alternate
Base  Rate"),  such rate to change on the  effective  date of any  change in the
Alternate Base Rate.

         "Alternate  Base Rate" shall mean,  for any day, a rate per annum equal
         to the  higher of (i) the Prime Rate in effect on such day and (ii) the
         Federal Funds Rate in effect on such day plus 1/2 of 1%.

For purposes of this definition:

         "Prime Rate" shall mean, for any day, the weighted average of the rates
         on overnight  Federal  funds  transactions  with members of the Federal
         Reserve System arranged by Federal funds brokers, as published for such
         day (or if such  day is not a  business  day,  for the  next  preceding
         business  day,  the  average  of  quotations   for  such  day  on  such
         transactions  received by the Bank from three  Federal funds brokers of
         recognized standing selected by the Bank.

All advances and all principal  payments hereunder shall be endorsed by the Bank
on the sheet  attached to the  Promissory  Grid Note and shall be secured by all
assets of the Borrower pursuant to a security agreement. The Borrower authorizes
the Bank to accept telephonic instructions from a duly authorized representative
of the Borrower,  as indicated by the latest  Corporate  Resolution on file with
the Bank, to make an advance or receive a repayment hereunder and to endorse the
sheet  attached to this  Promissory  Grid Note  accordingly.  All advances  made
hereunder shall be credited to the Borrower's deposit account referred to above,
which credits  shall be confirmed to the Borrower by standard  advice of credit.

<PAGE>

The Borrower agrees that the actual crediting of the sum of money so borrowed to
the Borrower's a deposit account shall constitute  conclusive  evidence that the
advance  was made,  and the  failure  of the Bank to  endorse  the amount of any
advance on the sheet  attached  to this note or to forward  to the  Borrower  an
advice of credit shall not affect the  obligation  of the Borrower to repay such
advance.

In  addition,  all  advances  under  the line of  credit  shall be  jointly  and
severally  guaranteed  by Health  Acquisition  Corp.,  National Home Health Care
Corp. and Accredited  Health  Services,  Inc. Each guarantee shall be secured by
all assets of the respective  guarantors pursuant to a security  agreement.  The
form of note, security agreement and guarantee to be furnished to the Bank shall
be in form and substance acceptable to the Bank and its counsel.

The amount of Loans  outstanding  under the line of credit  shall not exceed the
lesser of the Borrowing Base or $2,000,000 at any time. As used herein, the term
"Borrowing Base" shall mean (a) eighty percent (80%) of the Borrower's  Eligible
Accounts  Receivable  not more than 90 days past due from the invoice  date plus
(b) fifty percent (50%) of the Borrower's Estimated Unbilled Accounts Receivable
for the  Borrower's  previous  month.  The  Borrowing  Base shall be  calculated
pursuant to the Borrowing Base  Certificate set forth on Exhibit A. In the event
that the amount of the Loans  outstanding  hereunder  ever exceed the  Borrowing
Base, the Borrower shall prepay the outstanding Loans in such an amount as would
be  necessary  to bring  the  amount  outstanding  under  the line of  credit in
compliance with the terms and conditions hereof.

Advances  under the line of credit are subject to the Bank's  satisfaction  with
(i) the  specific  purpose and  expected  time and source of  repayment  of each
advance,  and (ii)  the  Borrower's  and the  guarantors'  financial  condition,
business  prospects and  operations  at the time of each  advance.  As you know,
lines of credit may be canceled  by either  party at any time,  however,  unless
canceled  earlier,  the line of credit shall be held available until January 31,
2001.

Additionally, all outstanding advances under the line of credit shall be reduced
to zero for a period of 30  consecutive  days  during  each  twelve  (12)  month
calendar period in which the line of credit is held available.

Sincerely,

THE BANK OF NEW YORK

/s/ Vito Caraccio
-----------------
Vito Caraccio
Vice President<PAGE>

                                                                    Exhibit 10.1

REVISED OFFER

November 22, 1999

Richard D. Gill, Ph.D.
937 Morris Avenue
Bryn Mawr, PA 19010

Dear Richard:

On behalf of Bob Hennessey, Chief Executive Officer, and the Board of Directors,
I am pleased to confirm our revised offer of employment for the position of
President and Chief Operating Officer for Genome Therapeutics Corporation,
reporting directly to Bob. We hope to have you assume your new role as soon as
you conclude your current commitments.

As President and Chief Operating Officer, you will have broad responsibility to
lead GTC business and scientific efforts and assume overall management
responsibility for all but the Human Resource function, which will continue to
report to Bob with a dotted line to you.

Our job offer includes the following components:

1.   BASE SALARY: $9,038.46 biweekly, which is $235,000 per annum.

2.   MANAGEMENT INCENTIVE PLAN: You will be eligible for an annual incentive of
     0 - 30% of base salary based on company performance. Incentive will most
     likely be paid in company stock.

3.   SIGNING BONUS: $15,000 cash bonus will be paid to you upon completion of 90
     days employment.

4.   RESTRICTED SHARES: You will be granted 20,000 restricted shares priced at
     the fair market value at date of acceptance. The shares will become
     exercisable in two (2) increments, 10,000 on your first anniversary with
     GTC and 10,000 at the conclusion of your second year of employment.

5.   STOCK OPTIONS: You will be nominated for a non-qualified stock option award
     equal to 240,000 options, which will vest in equal installments over four
     (4) years. The option price will be the fair market value of GTC stock at
     date of acceptance. Additionally you will be granted 100,000 performance
     based options which also vest in equal installments over four (4) years but
     can immediately vest in 50% increments if the stock price closes at $8.00
     and $10.00 respectively for 10 of 20 consecutive trading days. The option
     price for this grant will be the fair market value at date of acceptance.

6.   RELOCATION: Reasonable and customary relocation expenses with receipts and
     temporary living allowance will be covered up to $60,000 with full tax
     gross up. The allowance amount commitment will expire one (1) year from
     date of hire.

7.   BENEFITS: Eligibility to participate in our standard benefits program,
     which includes an initial five (5) weeks vacation. You will also be
     provided with Company paid executive life insurance equivalent to 3X base
     salary. A Company paid cellular telephone and in home computer will be
     provided to you.

<PAGE>

8.   MISC. ALLOWANCE: Annual (fiscal year) miscellaneous allowance of $4,500.

9.   SALARY PROTECTION: If you are terminated from the company for reasons other
     than cause within two (2) years from date of hire, you will be entitled to
     receive up to twelve (12) months salary and benefits continuation or until
     such time you are re-employed, whichever occurs first. Cause is defined as:

a)   Commission of any act of dishonesty or misconduct in respect of Employer or
     any person(s) either associated with Employer's business or with whom
     Employer does business.
b)   Absence from work for an extended period without permission of Employer.
c)   Consistent failure to obey directives of Employer.
d)   Dissemination without Employer's approval of any confidential information
     obtained in the course of employment to any person not employed by
     Employer.
e)   Failure to provide services in substantial compliance with the terms and
     provisions of this engagement.

1.   CHANGE OF CONTROL: If, within two (2) years following a change of control
     of the Company by a merger or if any person or group acquires a majority of
     the outstanding common stock of the Company, you are terminated, or you
     experience a material reduction in responsibilities or compensation, you
     will receive salary and benefits continuation for a period of twelve (12)
     months. Additionally, your remaining unvested options and non-exercisable
     restricted shares will immediately fully vest and become exercisable.

2.   BOARD SEAT: Based on your performance as determined by the Board and Bob
     Hennessey, over the course of six (6) months from date of hire, you will be
     considered for nomination to the Board. However, as President and COO, you
     will be a regularly invited guest to Board meetings except on matters
     deemed as Board only topics for discussions (i.e., your own compensation,
     CEO succession plan).

3.   PERFORMANCE REVIEW: Your first performance and merit review will be
     September 2000.You and I will discuss and agree on performance objectives
     shortly after you commence your employment with GTC.

Our offer of employment is contingent upon completion of positive references,
signing of this at will employment offer letter and acceptance of the terms and
conditions set forth in the company's Intellectual Property Policy, one of which
is enclosed for your review and signature. The top sheet of the IP Policy and
last page of Appendix I will need to be signed. Please note your acceptance of
our offer and terms by returning these signed documents to me. Once you have
confirmed your start date with me, arrangements will be made for your
orientation and public statement of your employment with the company.

This offer is valid until Wednesday, November 24, 1999.

Richard, Bob and the Board very much look forward to a positive response from
you, and anticipate your contributions to Genome Therapeutics Corporation.

Please call me with any questions you may have regarding this offer.

Sincerely,

Joseph A. Pane
Vice President, Human Resources
Genome Therapeutics Corporation

By signing below I accept the terms and conditions of this employment offer:

________________________           __________                      ____________
Richard D. Gill, Ph.D.                Date                           Start Date

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