Document:

VOTING AGREEMENT AND WAIVER

 EXHIBIT 10.1 
 VOTING AGREEMENT AND WAIVER 
 THIS VOTING AGREEMENT AND WAIVER (this “Agreement”), dated as
of April 17, 2006, is made by and among Hologic, Inc, a Delaware corporation (the “Buyer”) and holders (the “Stockholders”) of certain shares of Common Stock, $0.001 par value per share, and certain shares of Preferred
Stock, $0.001 par value per share, of Suros Surgical Systems, Inc., a Delaware corporation (the “Company”). Capitalized terms used but not defined herein have the meanings ascribed to them in the Merger Agreement (as defined below).

 WHEREAS, concurrently herewith, Buyer, Swordfish Acquisition, Inc., a wholly-owned subsidiary of the Buyer (“Merger Sub”), the
Company and the Stockholder Representative have entered into an Agreement and Plan of Merger (as the same may be amended from time to time, the “Merger Agreement”) providing for the merger of Merger Sub with and into the Company, subject
to the terms and conditions set forth in the Merger Agreement (the “Merger”), with the Company being the entity surviving the Merger; and 
 WHEREAS, each of the Stockholders owns of record and beneficially the number of outstanding shares of Common Stock and Preferred Stock of the Company set forth opposite her, his or its name as “Owned Shares” on Schedule A
attached hereto, and has voting power over such additional number of outstanding shares of Common Stock and Preferred Stock of the Company set forth opposite her, his or its name as “Controlled Shares” on Schedule A hereto
(collectively, the Owned Shares and Controlled Shares are referred to as “Shares”), and each Stockholder wishes to enter into this Agreement with respect to all of such Shares and any additional shares of Common or Preferred Stock of the
Company hereafter acquired; and 
 WHEREAS, in order to induce Buyer to enter into the Merger Agreement, Buyer has requested that the
Stockholders, and the Stockholders have agreed to, enter into this Agreement; 
 NOW, THEREFORE, for good and valuable consideration, the
receipt, sufficiency and adequacy of which are hereby acknowledged, the parties hereto agree as follows: 
 ARTICLE I 
 VOTING AGREEMENT; IRREVOCABLE GRANT OF PROXY; WAIVER 
 Section 1.1. Voting Agreement. (a) During the term of this Agreement, each Stockholder hereby agrees to vote all the Shares and any other capital stock that such Stockholder becomes entitled to vote,
whether through contract, purchase, exercise of an option or otherwise (“Additional Shares”) to approve and adopt the Merger Agreement (and any subsequent amendments thereto), the Merger and all other agreements and actions to be
undertaken in connection therewith, at every meeting of stockholders of Company, and at every adjournment thereof (or by written consent in lieu of a meeting), at which such matters are submitted for the consideration and vote of stockholders of
Company. Each Stockholder hereby further agrees that it will not vote (or give a written consent with respect to) any Shares or Additional Shares in favor of the approval of (i) any proposal or offer for a merger, consolidation, business
combination, tender offer, sale of substantial assets, sale of shares of capital stock or similar transactions involving Company or any of its subsidiaries, other than the transactions contemplated by the Merger Agreement, (ii) any
reorganization, recapitalization, liquidation, winding up of Company or any other extraordinary transaction involving Company, or (iii) any corporate action the consummation of which would frustrate the purposes, or prevent or delay the
consummation, of the Merger or the transactions contemplated by the Merger Agreement. 
  

			
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 (b) Except as set forth in clause (a) of this Section 1.1, the Stockholders shall not be
restricted from voting in favor of, against or abstaining with respect to any matter presented to the stockholders of the Company. 
 Section 1.2. Irrevocable Proxy. Each Stockholder hereby revokes any and all previous proxies granted with respect to such Stockholder’s Shares and/or Additional Shares with respect to the matters set forth in
Section 1.1(a). Each Stockholder hereby grants a proxy appointing Buyer as such Stockholder’s attorney-in-fact and proxy, with full power of substitution, for and in such Stockholder’s name, to vote, express consent or dissent, or
otherwise to utilize such voting power with respect to such Stockholder’s Shares and/or such Additional Shares in accordance with Section 1.1(a). The proxy granted by each Stockholder pursuant to this Section 1.2 is irrevocable to the
extent permitted by Delaware law, is coupled with an interest and is granted in consideration of Buyer’s entering into this Agreement and the Merger Agreement and incurring certain related fees and expenses. The proxy granted by each
Stockholder shall terminate in accordance with Section 4.4 of this Agreement. 
 Section 1.3. Waiver of Appraisal Rights.
Each Stockholder hereby agrees not to exercise her, his or its appraisal rights pursuant to Section 262 of the Delaware General Corporation Law or other relevant provisions with respect to the Merger, the Merger Agreement or the transactions
contemplated thereby. 
 ARTICLE II 
 REPRESENTATIONS AND WARRANTIES OF STOCKHOLDERS 
 Each Stockholder severally represents and warrants to Buyer that:

 Section 2.1. Valid Title. Such Stockholder is the sole record and beneficial owner of such Stockholder’s Owned Shares, and
there are no restrictions on such Stockholder’s voting rights with respect to such Shares. None of such Stockholder’s Owned Shares is subject to any voting trust or other agreement or arrangement with respect to the voting of such Owned
Shares. Each Stockholder has the sole right to vote the shares, if any, listed as Controlled Shares on Schedule A hereto. 
 Section 2.2. Non-Contravention. The execution, delivery and performance by such Stockholder of this Agreement and the consummation of the transactions contemplated hereby (i) are within such Stockholder’s powers, have
been duly authorized by all necessary action (including any consultation, approval or other action by or with any other person), (ii) require no action by or in respect of, or filing with, any governmental body, agency, official or authority,
and (iii) do not and will not violate, contravene or constitute a default under, or give rise to a right of termination, cancellation or acceleration of any right or obligation of such Stockholder or to a loss of any benefit of such Stockholder
under, any statute, rule or regulation applicable to such Stockholder or injunction, order, decree, or other instrument binding on such Stockholder or result in the imposition of any lien on any Shares or Additional Shares. 
 Section 2.3. Binding Effect. This Agreement has been duly executed and delivered by such Stockholder and, assuming this Agreement is the
valid and binding agreement of Buyer, is the valid and binding agreement of such Stockholder, enforceable against such Stockholder in accordance with its terms. If this Agreement is being executed in a representative or fiduciary capacity, the
person signing this Agreement has full power and authority to enter into and perform this Agreement. 
  

			
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 Section 2.4. Total Shares. As of the date hereof, such Stockholder is the legal and
beneficial owner of the number of Shares set forth opposite her, his or its name on Schedule A hereto, which Shares represent the only shares of capital stock of the Company legally or beneficially owned by such Stockholder and, except as set
forth on Schedule A, such Stockholder owns no options to purchase or rights to subscribe for or otherwise acquire any securities of Company and has no other interest in or voting rights with respect to any securities of Company. 

ARTICLE III 
 COVENANTS OF
STOCKHOLDERS 
 Each Stockholder, severally, in its capacity as a stockholder of the Company, hereby covenants and agrees that:

 Section 3.1. No Proxies for or Encumbrances on Stockholder Shares. Except as provided in this Agreement, such Stockholder shall
not, during the term of this Agreement, without the prior written consent of Buyer, directly or indirectly, (i) grant any proxies or enter into any voting trust or other agreement or arrangement with respect to the voting of any Shares or
Additional Shares, with respect to the matters set forth in Section 1.1, (ii) except as provided in Section 4.5, sell, assign, transfer, encumber or otherwise dispose of, or enter into any contract, option or other arrangement or
understanding with respect to the direct or indirect sale, assignment, transfer, encumbrance or other disposition of, any Shares or Additional Shares, or (iii) take any other action that would in any way restrict, limit or interfere with the
performance of the Stockholder’s obligations hereunder. 
 Section 3.2. Conduct of Stockholder. Such Stockholder will not
(i) take, or agree or commit to take, any action that would make any representation and warranty of such Stockholder hereunder inaccurate in any respect as of any time prior to the termination of this Agreement or (ii) omit, or agree or
commit to omit, to take any action necessary to prevent any such representation or warranty from being inaccurate in any respect at any such time. 
 ARTICLE IV 
 MISCELLANEOUS 
 Section 4.1. Further Assurances. Except as otherwise provided in the Merger Agreement, Stockholders will each execute and deliver or cause to be executed and delivered all further documents and instruments
and take such reasonable further action as may be reasonably necessary in order to consummate the transactions contemplated hereby. 
 Section 4.2. Specific Performance. The parties hereto agree and each Stockholder expressly acknowledges that Buyer may be irreparably damaged if for any reason any Stockholder fails to perform any of its obligations under this
Agreement, and that Buyer may not have any adequate remedy at law for money damages in such event. Accordingly, each Stockholder agrees that in the case of the failure of any Stockholder to perform Buyer shall be entitled to specific performance and
injunctive and other equitable relief to enforce the performance of this Agreement by each Stockholder, and further agrees that any such specific performance and injunctive and/or other equitable relief, in addition to remedies at law or damages, is
the appropriate remedy for any such failure to perform, and further agrees that such Stockholder will not seek, and agrees to waive any requirement for, the securing or posting of a bond in connection with Buyer’s seeking or obtaining such
equitable relief. This provision is without prejudice to any other rights that Buyer may have against any Stockholder for any failure to perform its obligations under this Agreement. 
  

			
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 Section 4.3. Notices. All notices, requests, demands, claims, and other communications
hereunder shall be in writing. Any notice, request, demand, claim, or other communication hereunder shall be deemed duly delivered on the date of receipt, if delivered by hand, or one business day after it is sent by receipt – confirmed
telecopy or via a reputable nationwide overnight courier service for next business day delivery, if to Buyer, at its address set forth below its signature hereto, together with a copy to Brown Rudnick Berlack Israels LLP One Financial Center,
Boston, Massachusetts 02111 (Attention: Philip J. Flink, Esq.); and if to a Stockholder, to such Stockholder at her, his or its address set forth on Schedule A hereto copy to [ (Attention: )]. Any party may give any notice, request, demand,
claim, or other communication hereunder using any other means (including expedited courier, messenger service, telecopy, mail, or electronic mail), but no such notice, request, demand, claim, or other communication shall be deemed to have been duly
given unless and until it actually is received by the party for whom it is intended. Any party may change the address to which notices, requests, demands, claims, and other communications hereunder are to be delivered by giving the other parties
notice in the manner herein set forth. 
 Section 4.4. Term of Agreement; Termination. The term of this Agreement shall commence
on the date hereof and such term, this Agreement and the proxy(ies) granted in and pursuant to Section 1.2 hereof shall terminate upon the earlier to occur of (i) the Effective Time (as defined in the Merger Agreement), (ii) the date
on which the Merger Agreement is terminated in and pursuant to accordance with its terms, or (iii) the date on which Buyer provides written notice of termination to Stockholders. Upon such termination, no party shall have any further
obligations or liabilities hereunder; provided, that such termination shall not relieve any party from liability for any willful breach of this Agreement prior to such termination. 
 Section 4.5. Survival of Representations and Warranties. All representations, warranties and covenants contained in this Agreement shall
survive delivery of and payment for the Shares. 
 Section 4.6. Permitted Transfers. Notwithstanding anything in this Agreement
to the contrary, each of the Stockholders may transfer any or all of the Shares and Additional Shares, in accordance with applicable Law, to such Stockholder’s spouse, ancestors, descendants or any trust or other entity controlled by such
Stockholder for any of their benefit; provided, however, that, prior to and as a condition to the effectiveness of such transfer, each Person to which any of such Shares or Additional Shares or any interest in any of such Shares or
Additional Shares is or may be transferred shall have executed and delivered to the Buyer a counterpart of this Agreement pursuant to which such Person shall be bound by all of the terms and provisions of this Agreement, and shall have agreed in
writing with the Buyer to hold such Shares or Additional Shares or interest in such Shares or Additional Shares subject to all of the terms and provisions of this Agreement. 
 Section 4.7. Amendments. This Agreement may not be modified, amended, altered or supplemented, except upon the execution and delivery of a
written agreement executed by the parties hereto. 
 Section 4.8. Successors and Assigns. The provisions of this Agreement shall
be binding upon and inure to the benefit of the parties hereto and their respective successors and assigns, provided that Buyer may assign its rights and obligations to any affiliate of Buyer and provided, further, that no Stockholder may assign,
delegate or otherwise transfer any of its rights or obligations under this Agreement without the consent of Buyer, except as otherwise provided in Section 4.5 hereof. 
 Section 4.9. Governing Law and Venue. THIS AGREEMENT SHALL BE DEEMED TO BE MADE IN, AND IN ALL RESPECTS SHALL BE INTERPRETED, CONSTRUED

  

			
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AND GOVERNED BY AND IN ACCORDANCE WITH THE LAWS OF THE STATE OF DELAWARE APPLICABLE TO CONTRACTS TO BE PERFORMED WHOLLY IN SUCH STATE. The parties hereby
(a) irrevocably submit to the jurisdiction of the Chancery Court of the State of Delaware and the federal courts of the United States of America located in the State of Delaware solely in respect of the interpretation and enforcement of the
provisions of this Agreement and in respect of the transactions contemplated hereby and (b) waive, and agree not to assert, as a defense in any action, suit or proceeding for the interpretation or enforcement hereof, that it is not subject to
such jurisdiction or that such action, suit or proceeding may not be brought or is not maintainable in said courts or that the venue thereof may not be appropriate or that this Agreement may not be enforced in or by such courts, and the parties
irrevocably agree that all claims with respect to such action or proceeding shall be heard and determined in such courts. The parties hereby consent to and grant any such court’s jurisdiction over the person of such parties and over the subject
matter of such dispute and agree that mailing of process or other papers in connection with any such action or proceeding in the manner provided in Section 4.3, or in such other manner as may be permitted by law, shall be valid and sufficient
service thereof. 
 Section 4.10. Entire Agreement. This Agreement supersedes all prior agreements, written or oral, between the
parties hereto with respect to the subject matter hereof and contains the entire agreement between the parties with respect to the subject matter hereof. This Agreement may not be amended, supplemented or modified, and no provisions hereof may be
modified or waived, except by an instrument in writing signed by the parties hereto. No waiver of any provision hereof by any party shall be deemed a waiver of any other provision hereof by such party, nor shall any such waiver be deemed a
continuing waiver of any provision hereof by such party. 
 Section 4.11. Severability. If any provision of this Agreement or the
application of such provision to any person or circumstances shall be held invalid or unenforceable by a court of competent jurisdiction, such provision or application shall be unenforceable only to the extent of such invalidity or unenforceability,
and the remainder of the provisions not held invalid or unenforceable and the application of such provisions to persons or circumstances other than the party as to which it is held invalid, and the remainder of this Agreement, shall not be affected.

 Section 4.12. Counterparts. This Agreement may be signed in any number of counterparts, each of which shall be an original,
with the same effect as if the signatures thereto and hereto were upon the same instruments. 
 Section 4.13. Headings. The
headings and captions used herein are inserted for convenience of reference only and are not intended to be part of or to affect the meaning or interpretation of this Agreement. 
 Section 4.14. Obligations Separate; Stockholder Capacity. The obligations of Stockholders hereunder are several and not joint. Each
Stockholder who is an individual signs solely in his capacity as the record holder and beneficial owner of, or the trustee of a trust whose beneficiaries are the beneficial owners of, such Stockholder’s Shares and any Additional Shares and
nothing herein shall limit or affect any actions taken by a Stockholder in his capacity as an officer or director of Company. The parties hereto acknowledge and agree that each Stockholder’s obligations hereunder are solely in his, her or its
capacity as a stockholder of the Company, and that none of the provisions herein set forth shall be deemed to (i) restrict or limit any fiduciary duty that any of the undersigned or any of their respective affiliates may have as a member of the
Board of Directors of the Company, as an officer of the Company, or otherwise as a fiduciary to any person resulting from any circumstances other than as a stockholder of the Company or (ii) limit or affect any action or inaction by any such
person to the extent specifically permitted by the Merger Agreement; provided that, no such duty shall excuse the Stockholder from his, her or its obligations as a stockholder of the Company to vote the Shares and any Additional Shares, to the
extent that they may be so voted, or otherwise perform any obligations as herein provided and to otherwise comply with the terms and conditions of this Agreement. 
  

			
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 Section 4.15. Construction. In the event of an ambiguity or a question of intent or
interpretation arises, this Agreement shall be construed as if drafted jointly by the parties and no presumption or burden of proof shall arise favoring or disfavoring any party by virtue of the authorship of any provisions of this Agreement.

 [Remainder of page intentionally blank; signature page follows.] 
  

			
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 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be duly executed as of the day and
year first above written. 
  

			
	HOLOGIC, INC.
		
	By:	 	 /s/ Glenn P. Muir

	Name:	 	Glenn P. Muir
	Title:	 	Executive Vice President and Chief Financial Officer
	
	STOCKHOLDERS:
		
	By:	 	 /s/ Jericho LLP,

		 	Joseph Mark,
		 	Managing Partner
		
	By:	 	 /s/ Mobius, L.P.,

		 	ME Miller,
		 	Managing Partner

  

			
	VOTING AGREEMENT AND WAIVER	 	Page 7

 Schedule A 
  

									
	  	  	Owned Shares	  	Controlled Shares
	 Stockholder
 Name and Address
	  	Common
Stock	  	Preferred
Stock	  	Common
Stock	  	 Preferred
 Stock

	 Joseph Mark
 Managing Partner
 Jericho Limited Partnership
 5154 N. Capitol Ave.
 Indianapolis, IN 46181
	  	2,101,666	  		  		  	
					
	 Michael Miller
 Managing Partner
 Mobius Limited Partnership
 4560 W. Woodpecker
 Tralfalgar, IN 46181
	  	2,133,686	  		  		  	

  

			
	VOTING AGREEMENT - FORM OF PROXYVOTING AGREEMENT AND WAIVER

 EXHIBIT 10.2 
 VOTING AGREEMENT AND WAIVER 
 THIS VOTING AGREEMENT AND WAIVER (this “Agreement”),
dated as of April 24, 2006, is made by and among Hologic, Inc., a Delaware corporation (the “Parent”) and holders (the “Principal Stockholders”) of certain shares of Company Capital Stock of R2 Technology,
Inc., a Delaware corporation (the “Company”). Capitalized terms used but not defined herein have the meanings ascribed to them in the Merger Agreement (as defined below). 
 WHEREAS, concurrently herewith, Parent, Hydrogen Acquisition, Inc., a Delaware corporation and a wholly-owned subsidiary of Parent (“Merger
Sub”), the Company, and Scott Halsted, solely in his capacity as the Stockholder Representative, have entered into an Agreement and Plan of Merger of even date herewith (as the same may be amended from time to time, the “Merger
Agreement”) providing for, among other things, the merger of Merger Sub with and into the Company, subject to the terms and conditions set forth in the Merger Agreement (the “Merger”), with the Company being the entity
surviving the Merger; and 
 WHEREAS, each of the Principal Stockholders, as of the date of this Agreement, is the record owner and the
“beneficial owner” (within the meaning of Rule 13d-3 under the Securities Exchange Act of 1934, as amended (the “Exchange Act”)) of the number of outstanding shares of Company Capital Stock set forth opposite her, his or
its name as “Shares” on Schedule A attached hereto, and each Principal Stockholder wishes to enter into this Agreement with respect to all of such Shares and any additional shares of capital stock of the Company that such
Principal Stockholder hereafter acquires the right to vote, whether through contract, purchase, exercise of an option or otherwise after the date of this Agreement (“Additional Shares”); and 
 WHEREAS, in order to induce Parent to enter into the Merger Agreement, Parent has requested that the Principal Stockholders, and the Principal
Stockholders have agreed to, enter into this Agreement; 
 NOW, THEREFORE, for good and valuable consideration, the receipt, sufficiency and
adequacy of which are hereby acknowledged, the parties hereto agree as follows: 
 ARTICLE I 
 VOTING AGREEMENT; IRREVOCABLE GRANT OF PROXY; WAIVER 
 Section 1.1. Voting Agreement. During the term of this Agreement, each Principal Stockholder hereby agrees to vote all the Shares and any Additional Shares to approve and adopt the Merger Agreement (and
any subsequent amendments thereto), the Merger and all other agreements and actions contemplated by the Merger Agreement to be undertaken in connection therewith, at every meeting of stockholders of the Company, and at every adjournment thereof (or
by written consent in lieu of a meeting), at which such matters are submitted for the consideration and vote of stockholders of the Company. Each Principal Stockholder hereby further agrees that it will not vote (or give a written consent with
respect to) any Shares or Additional Shares in favor of the approval of (i) any proposal or offer for a merger, 

 
consolidation, business combination, tender offer, sale of substantial assets, sale of shares of capital stock or extraordinary transactions involving the
Company or any of its subsidiaries, other than the transactions contemplated by the Merger Agreement, (ii) any reorganization, recapitalization, liquidation or winding up of the Company or any other extraordinary corporate transaction involving
the Company (other than the conversion of all shares of Company Preferred Stock into Company Common Stock pursuant to the Company Certificate of Incorporation as contemplated by Section 1.7(a) of the Merger Agreement hereof), or (iii) any
corporate action the consummation of which would reasonably be expected to frustrate the purposes, or prevent or delay the consummation, of the Merger or the transactions contemplated by the Merger Agreement. 
 Section 1.2. Irrevocable Proxy. Each Principal Stockholder hereby revokes any and all previous proxies granted with respect to such Principal
Stockholder’s Shares and/or Additional Shares. Each Principal Stockholder hereby grants a proxy appointing Parent as such Principal Stockholder’s attorney-in-fact and proxy, with full power of substitution, for and in such Principal
Stockholder’s name, to vote such Principal Stockholder’s Shares and/or Additional Shares in favor of (a) the Merger, the execution and delivery by the Company of the Merger Agreement and the adoption and approval of the Merger
Agreement and the terms thereof, (b) in favor of each of the other actions contemplated by the Merger Agreement and (c) in favor of any action in furtherance of any of the foregoing; and against (x) any proposal or offer for a merger,
consolidation, business combination, tender offer, sale of substantial assets, sale of shares of capital stock or similar transactions involving the Company or any of its subsidiaries, other than the transactions contemplated by the Merger
Agreement, (y) any reorganization, recapitalization, liquidation or winding up of the Company or any other extraordinary transaction involving the Company (other than the conversion of all shares of Company Preferred Stock into Company Common
Stock pursuant to the Company Certificate of Incorporation as contemplated by Section 1.7(a) of the Merger Agreement), or (z) any corporate action the consummation of which would reasonably be expected to frustrate the purposes, or prevent
or delay the consummation, of the Merger or the transactions contemplated by the Merger Agreement. Simultaneously with the execution and delivery of this Agreement, each Principal Stockholder is delivering to the Parent a proxy in the Form of
Annex A hereto. The proxy granted by each Principal Stockholder pursuant to this Section 1.2 is irrevocable to the extent permitted by Delaware law, is coupled with an interest and is granted in consideration of Parent’s entering
into this Agreement and the Merger Agreement and incurring certain related fees and expenses. The proxy granted by each Principal Stockholder shall terminate on the Voting Covenant Expiration Date. 
 Section 1.3. Waiver of Appraisal Rights. Each Principal Stockholder hereby agrees not to exercise her, his or its appraisal rights pursuant
to Section 262 of the Delaware General Corporation Law or other relevant provisions with respect to the Merger, the Merger Agreement or the transactions contemplated thereby. 
  

			
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 ARTICLE II 
 REPRESENTATIONS AND WARRANTIES OF STOCKHOLDERS 
 Each Principal Stockholder severally represents and
warrants to Parent that: 
 Section 2.1. Valid Title. Such Principal Stockholder is the lawful record and beneficial owner of such
Principal Stockholder’s Shares, free and clear of any lien, charge, encumbrance or claim of whatever nature. None of such Principal Stockholder’s Shares is subject to any voting trust or other agreement or arrangement with respect to the
voting of such Shares, except as otherwise set forth on Schedule B hereto. 
 Section 2.2. Non-Contravention. The
execution, delivery and performance by such Principal Stockholder of this Agreement and the consummation of the transactions contemplated hereby (i) is within such Principal Stockholder’s powers, have been duly authorized by all necessary
action, and no other actions on the part of such Principal Stockholder are necessary to authorize the Agreement or to consummate the transactions contemplated hereby, and (ii) does not and will not (A) violate, contravene or constitute a
default under, (B) give rise to a right of termination, cancellation or acceleration of any right or obligation of such Principal Stockholder under, any statute, rule or regulation applicable to such Principal Stockholder or injunction, order
or decree binding on such Principal Stockholder or (C) result in the imposition of any lien on any Shares or Additional Shares. 
 Section 2.3. Binding Effect. This Agreement has been duly executed and delivered by such Principal Stockholder and is the valid and binding agreement of such Principal Stockholder, enforceable against such Principal Stockholder
in accordance with its terms, except: (i) as such enforceability may be limited by bankruptcy, insolvency, reorganization or similar laws affecting creditors’ rights generally; and (ii) that the remedy of specific performance and
injunctive and other forms of equitable relief may be subject to equitable defenses and to the discretion of the court before which any proceeding therefor may be brought. If this Agreement is being executed in a representative or fiduciary
capacity, the person signing this Agreement ahs full power and authority to enter into and perform this Agreement. 
 Section 2.4.
Shares. As of the date hereof, (a) such Principal Stockholder is the legal and beneficial owner of the number of Shares set forth opposite her, his or its name on Schedule A hereto, which Shares represent the only shares of
capital stock of the Company legally or beneficially owned by such Principal Stockholder, and (b) except as set forth on Schedule A, such Principal Stockholder owns no options or warrants to purchase or other rights to subscribe for or
otherwise acquire any securities of the Company. 
 Section 2.5. Accuracy of Representations. The representations and warranties
contained in this Agreement are accurate in all respects as of the date of this Agreement, will be accurate in all respects at all times through the Voting Covenant Expiration Date and will be accurate in all respects as of the date of the
consummation of the Merger as if made on that date. 
  

			
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 ARTICLE III 
 COVENANTS OF STOCKHOLDERS 
 Each Principal Stockholder, in its capacity as a stockholder of the
Company, hereby covenants and agrees that: 
 Section 3.1. No Proxies for, or Encumbrances on, Principal Stockholder Shares.
Except as provided in this Agreement, such Principal Stockholder shall not, during the term of this Agreement, without the prior written consent of Parent, directly or indirectly, (i) grant any proxies or enter into any voting trust or other
agreement or arrangement with respect to the voting of any Shares or Additional Shares to any person other than Parent, (ii) sell, assign, transfer, encumber or otherwise dispose of, or enter into any contract, option or other arrangement or
commitment with respect to the direct or indirect sale, assignment, transfer, encumbrance or other disposition of, any Shares or Additional Shares to any person other than Parent (other than the conversion of all shares of Company Preferred Stock
into Company Common Stock pursuant to the Company Certificate of Incorporation as contemplated by Section 1.7 of the Merger Agreement), or (iii) take any other action that would in any way restrict, limit or interfere with the performance
of such Principal Stockholder’s obligations hereunder or the transactions contemplated hereby. 
 ARTICLE IV 
 MISCELLANEOUS 
 Section 4.1.
Further Assurances. Except as otherwise provided in the Merger Agreement, from time to time, each Principal Stockholder will, at the request of Parent, execute and deliver or cause to be executed and delivered all further documents and
instruments and use their respective reasonable best efforts to secure such consents and take all such further action reasonably necessary for the purpose of carrying out and furthering the intent of this Agreement. 
 Section 4.2. Specific Performance. The parties hereto agree and each Principal Stockholder expressly acknowledges that Parent may be
irreparably damaged if for any reason any Principal Stockholder fails to perform any of its obligations under this Agreement, and that Parent would not have any adequate remedy at law for money damages in such event. Accordingly, each Principal
Stockholder agrees that in the case of the failure of any Principal Stockholder to perform, Parent shall be entitled to specific performance and injunctive and other equitable relief to enforce the performance of this Agreement by such nonperforming
Principal Stockholder, and further agrees that any such specific performance and injunctive and/or other equitable relief, in addition to remedies at law or damages, is the appropriate remedy for any such failure to perform, and further agrees that
such Principal Stockholder will not seek, and agrees to waive any requirement for, the securing or posting of a bond in connection with Parent’s seeking or obtaining such equitable relief. This provision is without prejudice to any other rights
that Parent may have against any Principal Stockholder for any failure to perform its obligations under this Agreement. 
  

			
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 Section 4.3. Notices. All notices, requests, demands, claims, and other communications
hereunder shall be in writing. Any notice, request, demand, claim, or other communication hereunder shall be deemed duly delivered on the date of receipt, if delivered by hand, two (2) business days after it is sent by registered or certified
mail, return receipt requested, postage prepaid, or one business day after it is sent by receipt – confirmed telecopy or via a reputable nationwide overnight courier service for next business day delivery, if to Parent, at its address set forth
below its signature hereto, together with a copy to Brown Rudnick Berlack Israels LLP, One Financial Center, Boston, Massachusetts 02111 (Attention: Philip J. Flink, Esq.); and if to a Principal Stockholder, to such Principal Stockholder at her, his
or its address set forth on Schedule A hereto with a copy to each of R2 Technology, Inc., 1195 West Fremont Avenue Sunnyvale, CA 94087 (Attention: John Pavlidis), and Latham & Watkins LLP, 135 Commonwealth Drive, Menlo Park,
California 94025 (Attention: Patrick A. Pohlen, Esq.). Any party may change the address to which notices, requests, demands, claims, and other communications hereunder are to be delivered by giving the other parties notice in the manner herein set
forth. 
 Section 4.4. Term of Agreement; Voting Covenant Expiration Date. The term of this Agreement shall commence on the date
hereof, and such term, this Agreement and the proxy(ies) granted in and pursuant to Section 1.2 hereof shall terminate upon the earliest to occur of (i) the Effective Time, (ii) the date on which the Merger Agreement is terminated in
accordance with its terms, and (iii) the date on which Parent provides written notice of termination of this Agreement to the Principal Stockholders (such date, the “Voting Covenant Expiration Date”). Upon such termination, no
party shall have any further obligations or liabilities hereunder; provided, that such termination shall not relieve any party from liability for any breach of this Agreement prior to such termination. 
 Section 4.5. Survival of Representations and Warranties. All representations, warranties and covenants contained in this Agreement shall
survive delivery of and payment for the Shares. 
 Section 4.6. Successors and Assigns. The provisions of this Agreement shall be
binding upon and inure to the benefit of the parties hereto and their respective successors and assigns, provided that Parent may assign its rights and obligations to any affiliate of Parent and provided, further, that no Principal Stockholder may
assign, delegate or otherwise transfer any of its rights or obligations under this Agreement without the consent of Parent. 
 Section 4.7. Governing Law and Venue. THIS AGREEMENT SHALL BE DEEMED TO BE MADE IN, AND IN ALL RESPECTS SHALL BE INTERPRETED, CONSTRUED AND GOVERNED BY AND IN ACCORDANCE WITH THE LAWS OF THE STATE OF DELAWARE APPLICABLE TO
CONTRACTS TO BE PERFORMED WHOLLY IN SUCH STATE. The parties hereby (a) irrevocably submit to the jurisdiction of the Chancery Court of the State of Delaware and the federal courts of the United States of America located in the State of Delaware
solely in respect of the interpretation and enforcement of the provisions of this Agreement and in respect of the transactions contemplated hereby and thereby and (b) waive, and agree not to assert, as a defense in any action, suit or
proceeding for the interpretation or enforcement hereof, that it is not subject to such jurisdiction or that such action, suit or proceeding may not be brought or is not maintainable in said courts or that the venue thereof 

  

			
	VOTING AGREEMENT AND WAIVER	 	Page 5

 
may not be appropriate or that this Agreement may not be enforced in or by such courts, and the parties irrevocably agree that all claims with respect to
such action or proceeding shall be heard and determined in such courts. The parties hereby consent to and grant any such court’s jurisdiction over the person of such parties and over the subject matter of such dispute and agree that mailing of
process or other papers in connection with any such action or proceeding in the manner provided in Section 4.3 hereof. 
 Section 4.8. Entire Agreement, Amendments, Waivers. This Agreement supersedes all prior agreements, written or oral, between the parties hereto with respect to the subject matter hereof and contains the entire agreement between
the parties with respect to the subject matter hereof. This Agreement may not be amended, supplemented or modified, and no provisions hereof may be modified or waived, except by an instrument in writing signed by the parties hereto. No waiver of any
provision hereof by any party shall be deemed a waiver of any other provision hereof by such party, nor shall any such waiver be deemed a continuing waiver of any provision hereof by such party. 
 Section 4.9. Severability. If any provision of this Agreement or the application of such provision to any person or circumstances shall be
held invalid or unenforceable by a court of competent jurisdiction, such provision or application shall be unenforceable only to the extent of such invalidity or unenforceability, and the remainder of the provisions not held invalid or unenforceable
and the application of such provisions to persons or circumstances other than the party as to which it is held invalid, and the remainder of this Agreement, shall not be affected. 
 Section 4.10. Counterparts. This Agreement may be signed in any number of counterparts, each of which shall be an original, with the same
effect as if the signatures thereto and hereto were upon the same instruments. 
 Section 4.11. Headings. The headings and
captions used herein are inserted for convenience of reference only and are not intended to be part of or to affect the meaning or interpretation of this Agreement. 
 Section 4.12. Obligations Separate; Principal Stockholder Capacity Only. All representations, warranties, covenants, agreements and obligations of Principal Stockholders hereunder are several and not
joint, and solely relate to matters involving the subject Principal Stockholder, and not the other Principal Stockholders. The parties hereto acknowledge and agree that each Principal Stockholder’s obligations hereunder are solely in his, her
or its capacity as a stockholder of the Company, and that none of the provisions set forth in this agreement shall restrict or otherwise limit such Principal Stockholder, and nothing herein shall limit or affect the duties of or any actions taken by
a Principal Stockholder (or any of their respective Affiliates) in each case, in his or her capacity as an officer or director of the Company (or otherwise as a fiduciary to any person resulting from any circumstances other than as a stockholder of
the Company). 
 Section 4.13. Construction. In the event of an ambiguity or a question of intent or interpretation arises, this
Agreement shall be construed as if drafted jointly by the parties and no presumption or burden of proof shall arise favoring or disfavoring any party by virtue of the authorship of any provisions of this Agreement. 
  

			
	VOTING AGREEMENT AND WAIVER	 	Page 6

 IN WITNESS WHEREOF, the parties hereto have caused this Voting Agreement and Waiver to be duly executed
as of the day and year first above written. 
  

			
	HOLOGIC, INC.
		
	By:	 	 /s/ Glenn P. Muir

	Name:	 	Glenn P. Muir
	Title:	 	Executive Vice President, Chief Financial Officer, Treasurer
	Address	 	 35 Crosby Drive
 Bedford, MA
01730

  

			
	VOTING AGREEMENT AND WAIVER	 	Page 7

			
	[SIGNATURE PAGE]
	
	PRINCIPAL STOCKHOLDER:
	
	ALTA V LIMITED PARTNERSHIP
	By: Alta V Management Partners, L.P.
		
	By:	 	 /s/ Eileen McCarthy

	Name:	 	Eileen McCarthy
	Title:	 	General Partner
	Address:	 	c/o Alta Communications
		 	200 Calrendon St.
		 	Floor 51
		 	Boston, MA 02166
	
	CUSTOMS HOUSE PARTNERS
		
	By:	 	 /s/ Eileen McCarthy

	Name:	 	Eileen McCarthy
	Title:	 	Under Power of Attorney
	Address:	 	c/o Alta Communications
		 	200 Calrendon St.
		 	Floor 51
		 	Boston, MA 02166
	
	ARCH VENTURE FUND III, L.P.
	By: ARCH Venture Partners, LLC, its general partner
		
	By:	 	 /s/ Steven Lazarus

	Name:	 	Steven Lazarus
	Title:	 	Managing Director
	Address:	 	8725 W. Higgins Road
		 	Suite 290
		 	Chicago, IL 60631
	
	 ARCH VENTURE FUND II, L.P.
 a Delaware
limited partnership

	
	 By: ARCH MANAGEMENT PARTNERS II, L.P.
 a
Delaware limited partnership, its general partner

	
	 By ARCH Venture Partners, L.P.
 a Delaware
limited partnership, its general partner

  

			
	VOTING AGREEMENT AND WAIVER	 	Page 8

			
	By: ARCH Venture Corporation
	an Illinois corporation, its general partner
		
	By:	 	 /s/ Steven Lazarus

	Name:	 	Steven Lazarus
	Title:	 	Managing Director
	Address:	 	8725 W. Higgins Road
		 	Suite 290
		 	Chicago, IL 60631
	
	MORGAN STANLEY VENTURE PARTNERS III, L.P.
	
	By: Morgan Stanley Venture Partners III, L.L.C., its General Partner
	
	By: Morgan Stanley Venture Capital III, Inc., its Institutional Managing Member
		
	By:	 	 /s/ Scott Halstead

	Name:	 	Scott Halstead
	Title:	 	Managing Member
	
	MORGAN STANLEY VENTURE INVESTORS III, L.P.
	
	By: Morgan Stanley Venture Partners III, L.L.C., its General Partner
	
	By: Morgan Stanley Venture Capital III, Inc., its Institutional Managing Member
		
	By:	 	 /s/ Scott Halstead

	Name:	 	Scott Halstead
	Title:	 	Managing Member
	
	SIGMA PARTNERS II, L.P.
	
	By: SIGMA MANAGEMENT II, L.P., its General Partner
		
	By:	 	 /s/ J. Burgess Jamieson

	Name:	 	J. Burgess Jamieson
	Title:	 	Managing General Partner
	Address:	 	1600 El Camino Real
		 	Suite 280
		 	Menlo Park, CA 94025
	
	SIGMA ASSOCIATES II, L.P.
	
	By: SIGMA MANAGEMENT II, L.P., its General Partner
		
	By:	 	 /s/ J. Burgess Jamieson

	Name:	 	J. Burgess Jamieson
	Title:	 	Managing General Partner
	Address:	 	1600 El Camino Real
		 	Suite 280
		 	Menlo Park, CA 94025

  

			
	VOTING AGREEMENT AND WAIVER	 	Page 9

 Schedule A 
  

					
	 	  	Shares
	 Principal Stockholder
 Name and Address
	  	Number
of Shares
of
Common
Stock	  	 Number of Shares and Series of Preferred Stock

	Alta V Limited Partnership	  	0	  	 989,600 shares of Series A-1 Preferred Stock
 358,417
shares of Series B-1 Preferred Stock
 742,200 shares of Series C-1 Preferred Stock
 346,953 shares of Series D-1 Preferred Stock
 76,123 shares of Series E-1 Preferred Stock
 130,627 shares of Series F-1 Preferred Stock
 49,480 shares of Series G-1
Preferred Stock

			
	Customs House Partners	  	0	  	 10,400 shares of Series A-1 Preferred Stock
 3,767 shares
of Series B-1 Preferred Stock
 7,800 shares of Series C-1 Preferred Stock
 3,646 shares of Series D-1 Preferred Stock
 800 shares of Series E-1 Preferred Stock
 1,373 shares of Series F-1 Preferred Stock
 520 shares of Series G-1 Preferred Stock

			
	ARCH Venture Fund III, L.P.	  	0	  	 375,000 shares of Series C-1 Preferred Stock
 392,903
shares of Series D-1 Preferred Stock
 133,809 shares of Series E-1 Preferred Stock
 13,333 shares of Series F-1 Preferred Stock
 37,500 shares of Series G-1 Preferred Stock

  

			
	VOTING AGREEMENT AND WAIVER	 	Page 10

					
	ARCH Venture Fund II, L.P.	  	0	  	 500,000 shares of Series A-1 Preferred Stock
 264,425
shares of Series B-1 Preferred Stock
 13,333 shares of Series F-1 Preferred Stock
 37,500 shares of Series G-1 Preferred Stock

			
	Morgan Stanley Venture Partners III, L.P.	  	447,074	  	 3,193,388 shares of Series C-1 Preferred Stock
 486,756
shares of Series D-1 Preferred Stock
 70,184 shares of Series E-1 Preferred Stock
 182,479 shares of Series F-1 Preferred Stock
 114,050 shares of Series G-1 Preferred Stock

			
	Morgan Stanley Venture Investors III, L.P.	  	42,926	  	 306,612 shares of Series C-1 Preferred Stock
 46,736
shares of Series D-1 Preferred Stock
 6,739 shares of Series E-1 Preferred Stock
 17,521 shares of Series F-1 Preferred Stock
 10,950 shares of Series G-1 Preferred Stock

			
	Sigma Partners II, L.P.	  	246,500	  	 929,600 shares of Series A-1 Preferred Stock
 336,832
shares of Series B-1 Preferred Stock
 348,780 shares of Series C-1 Preferred Stock
 272,897 shares of Series D-1 Preferred Stock
 100,154 shares of Series E-1 Preferred Stock
 99,199 shares of Series F-1 Preferred Stock
 23,250 shares of Series G-1
Preferred Stock

			
	Sigma Associates II, L.P.	  	18,554	  	 70,400 shares of Series A-1 Preferred Stock
 25,353
shares of Series B-1 Preferred Stock
 26,220 shares of Series C-1 Preferred Stock
 20,542 shares of Series D-1 Preferred Stock
 7,538 shares of Series E-1 Preferred Stock
 7,467 shares of Series F-1 Preferred Stock
 1,750 shares of Series G-1
Preferred Stock

  

			
	VOTING AGREEMENT AND WAIVER	 	Page 11

 Annex A 
 PROXY 
 The undersigned, for consideration received, hereby appoints Hologic, Inc., a Delaware
corporation (“Parent”), its proxy, with full power of substitution, to vote all shares of capital stock owned or later acquired by the undersigned, and all shares that the undersigned is or becomes entitled to vote pursuant to
contract, trust, deed or otherwise, at every meeting of stockholders of R2 Technology, Inc., a Delaware corporation (“Company”), and at every adjournment thereof (and by written consent in lieu of a meeting if any such matters are
submitted for the consideration and vote of stockholders of the Company thereby), to be held for the purpose of voting upon a proposal to approve and adopt the Agreement and Plan of Merger, dated as of April 24, 2006 (the “Merger
Agreement”), by and among Parent, Hyrdrogen Acquisition, Inc., a Delaware corporation, the Company and the Stockholder Representative, solely in such representative capacity, the Merger (as defined in the Merger Agreement) and all
agreements and actions contemplated by the Merger Agreement FOR such proposal and AGAINST: (i) any proposal or offer for a merger, consolidation, business combination, tender offer, sale of substantial assets, sale of shares of capital stock or
similar transactions involving the Company or any of its subsidiaries, other than the transactions contemplated by the Merger Agreement, (ii) any reorganization, recapitalization, liquidation or winding up of the Company or any other
extraordinary transaction involving the Company (other than the conversion of all shares of Company Preferred Stock into Company Common Stock pursuant to the Company Certificate of Incorporation as contemplated by Section 1.7 of the Merger
Agreement), or (iii) any corporate action the consummation of which would reasonably be expected to frustrate the purposes, or prevent or delay the consummation, of the Merger or the transactions contemplated by the Merger Agreement.

 Each Principal Stockholder may vote his, her or its Shares and/or Additional Shares on all matters not referred to in this proxy, and the
attorneys and proxies named above may not exercise this proxy with respect to such other matters. 
 This proxy is subject to the terms of
that certain Voting Agreement and Waiver dated as of April 24, 2006 between the undersigned and Parent, a copy of which is attached hereto (the “Voting Agreement”), is coupled with an interest, revokes all prior proxies granted
by the undersigned with respect to such shares, is irrevocable and shall terminate and be of no further force or effect automatically on the Voting Covenant Expiration Date (as defined in the Voting Agreement). 
 [PROXY SIGNATURE PAGE FOLLOWS] 
  

			
	 VOTING AGREEMENT - FORM OF PROXY
	 	

			
	 [PROXY SIGNATURE PAGE]

 Dated: April 24, 2006 
  

			
	ALTA V LIMITED PARTNERSHIP
	By: Alta V Management Partners, L.P.
		
	By:	 	 /s/ Eileen McCarthy

	Name:	 	Eileen McCarthy
	Title:	 	General Partner
	Address:	 	c/o Alta Communications
		 	200 Calrendon St.
		 	Floor 51
		 	Boston, MA 02166
	
	CUSTOMS HOUSE PARTNERS
		
	By:	 	 /s/ Eileen McCarthy

	Name:	 	Eileen McCarthy
	Title:	 	Under Power of Attorney
	Address:	 	c/o Alta Communications
		 	200 Calrendon St.
		 	Floor 51
		 	Boston, MA 02166
	
	ARCH VENTURE FUND III, L.P.
	By: ARCH Venture Partners, LLC, its general partner
		
	By:	 	 /s/ Steven Lazarus

	Name:	 	Steven Lazarus
	Title:	 	Managing Director
	Address:	 	8725 W. Higgins Road
		 	Suite 290
		 	Chicago, IL 60631
	
	 ARCH VENTURE FUND II, L.P.
 a Delaware
limited partnership

  

			
	 VOTING AGREEMENT - FORM OF PROXY
	 	

			
	By: ARCH MANAGEMENT PARTNERS II, L.P.
	a Delaware limited partnership, its general partner
	
	 By ARCH Venture Partners, L.P.
 a Delaware
limited partnership, its general partner

	
	By: ARCH Venture Corporation an Illinois corporation, its general partner
		
	By:	 	 /s/ Steven Lazarus

	Name:	 	Steven Lazarus
	Title:	 	Managing Director
	Address:	 	8725 W. Higgins Road
		 	Suite 290
		 	Chicago, IL 60631
	
	MORGAN STANLEY VENTURE PARTNERS III, L.P.
	
	By: Morgan Stanley Venture Partners III, L.L.C., its General Partner
	
	By: Morgan Stanley Venture Capital III, Inc., its Institutional Managing Member
		
	By:	 	 /s/ Scott Halstead

	Name:	 	Scott Halstead
	Title:	 	Managing Member
	
	MORGAN STANLEY VENTURE INVESTORS III, L.P.
	
	By: Morgan Stanley Venture Partners III, L.L.C., its General Partner
	
	By: Morgan Stanley Venture Capital III, Inc., its Institutional Managing Member
		
	By:	 	 /s/ Scott Halstead

	Name:	 	Scott Halstead
	Title:	 	Managing Member
	
	SIGMA PARTNERS II, L.P.
	
	By: SIGMA MANAGEMENT II, L.P., its General Partner
		
	By:	 	 /s/ J. Burgess Jamieson

	Name:	 	J. Burgess Jamieson
	Title:	 	Managing General Partner
	Address:	 	1600 El Camino Real
		 	Suite 280
		 	Menlo Park, CA 94025
	
	SIGMA ASSOCIATES II, L.P.
	
	By: SIGMA MANAGEMENT II, L.P., its General Partner
		
	By:	 	 /s/ J. Burgess Jamieson

	Name:	 	J. Burgess Jamieson
	Title:	 	Managing General Partner
	Address:	 	1600 El Camino Real
		 	Suite 280
		 	Menlo Park, CA 94025

  

			
	 VOTING AGREEMENT - FORM OF PROXY

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