Document:

EXHIBIT 10.5

      THIS NOTE AND THE COMMON SHARES ISSUABLE UPON CONVERSION OF THIS NOTE HAVE
      NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. THIS
      NOTE AND THE COMMON SHARES ISSUABLE UPON CONVERSION OF THIS NOTE MAY NOT
      BE SOLD, OFFERED FOR SALE, PLEDGED OR HYPOTHECATED IN THE ABSENCE OF AN
      EFFECTIVE REGISTRATION STATEMENT AS TO THIS NOTE UNDER SAID ACT OR AN
      OPINION OF COUNSEL REASONABLY SATISFACTORY TO ADDISON-DAVIS DIAGNOSTICS,
      INC. THAT SUCH REGISTRATION IS NOT REQUIRED.

                            SECURED CONVERTIBLE NOTE

      FOR VALUE RECEIVED, ADDISON-DAVIS DIAGNOSTICS, INC., a Delaware
corporation (hereinafter called "Borrower"), hereby promises to pay to ALPHA
CAPITAL AKTIENGESELLSCHAFT, Pradafant 7, 9490 Furstentums, Vaduz, Lichtenstein,
Fax: 011-42-32323196 (the "Holder") or order, without demand, the sum of One
Hundred and Thirty-Two Thousand Dollars ($132,000.00), with unpaid interest
accruing on December 23, 2007 (the "Maturity Date"), or sooner as described
herein.

      This Note has been entered into pursuant to the terms of a subscription
agreement between the Borrower and the Holder, dated of even date herewith (the
"Subscription Agreement"), and shall be governed by the terms of such
Subscription Agreement. Unless otherwise separately defined herein, all
capitalized terms used in this Note shall have the same meaning as is set forth
in the Subscription Agreement. The following terms shall apply to this Note:

                                    ARTICLE I

                               GENERAL PROVISIONS

      1.1 Payment Grace Period. The Borrower shall have a ten (10) day grace
period to pay any monetary amounts due under this Note, after which grace period
a default interest rate of fifteen percent (15%) per annum shall apply to the
amounts owed hereunder.

      1.2 Conversion Privileges. The Conversion Privileges set forth in Article
II shall remain in full force and effect immediately from the date hereof and
until the Note is paid in full regardless of the occurrence of an Event of
Default. The Note shall be payable in full on the Maturity Date, unless
previously converted into Common Stock in accordance with Article II hereof;
provided, that if an Event of Default has occurred, the Borrower may not pay
this Note, without the consent of the Holder, until one year after the later of
the date the Event of Default has been cured or one year after the Maturity
Date.

<PAGE>

                                   ARTICLE II

                               CONVERSION RIGHTS

      The Holder shall have the right to convert the principal due under this
Note into Shares of the Borrower's Common Stock, $.001 par value per share
("Common Stock") as set forth below.

      2.1. Conversion into the Borrower's Common Stock.

            (a) The Holder shall have the right from and after the date of the
issuance of this Note and then at any time until this Note is fully paid, to
convert any outstanding and unpaid principal portion of this Note, and accrued
interest, at the election of the Holder (the date of giving of such notice of
conversion being a "Conversion Date") into fully paid and nonassessable shares
of Common Stock as such stock exists on the date of issuance of this Note, or
any shares of capital stock of Borrower into which such Common Stock shall
hereafter be changed or reclassified, at the conversion price as defined in
Section 2.1(b) hereof (the "Conversion Price"), determined as provided herein.
Upon delivery to the Borrower of a completed Notice of Conversion, a form of
which is annexed hereto, Borrower shall issue and deliver to the Holder within
three (3) business days from the Conversion Date (such third day being the
"Delivery Date") that number of shares of Common Stock for the portion of the
Note converted in accordance with the foregoing. At the election of the Holder,
the Borrower will deliver accrued but unpaid interest, if any, on the Note
through the Conversion Date directly to the Holder on or before the Delivery
Date (as defined in the Subscription Agreement). The number of shares of Common
Stock to be issued upon each conversion of this Note shall be determined by
dividing that portion of the principal of the Note and interest to be converted,
by the Conversion Price.

            (b) Subject to adjustment as provided in Section 2.1(c) hereof, the
Conversion Price per share shall be equal to the lessor of (i) $0.07, or (ii)
65% of the average of the three lowest intra-day trading prices of the Common
Stock as reported by Bloomberg L.P. for the twenty trading days preceding a
Conversion Date.

            (c) The Conversion Price and number and kind of shares or other
securities to be issued upon conversion determined pursuant to Section 2.1(a),
shall be subject to adjustment from time to time upon the happening of certain
events while this conversion right remains outstanding, as follows:

                  A. Merger, Sale of Assets, etc. If the Borrower at any time
shall consolidate with or merge into or sell or convey all or substantially all
its assets to any other corporation, this Note, as to the unpaid principal
portion thereof and accrued interest thereon, shall thereafter be deemed to
evidence the right to purchase such number and kind of shares or other
securities and property as would have been issuable or distributable on account
of such consolidation, merger, sale or conveyance, upon or with respect to the
securities subject to the conversion or purchase right immediately prior to such
consolidation, merger, sale or conveyance. The foregoing provision shall
similarly apply to successive transactions of a similar nature by any such
successor or purchaser. Without limiting the generality of the foregoing, the
anti-dilution provisions of this Section shall apply to such securities of such
successor or purchaser after any such consolidation, merger, sale or conveyance.

                  B. Reclassification, etc. If the Borrower at any time shall,
by reclassification or otherwise, change the Common Stock into the same or a
different number of securities of any class or classes that may be issued or
outstanding, this Note, as to the unpaid principal portion thereof and accrued
interest thereon, shall thereafter be deemed to evidence the right to purchase
an adjusted number of such securities and kind of securities as would have been
issuable as the result of such change with respect to the Common Stock
immediately prior to such reclassification or other change.

<PAGE>

                  C. Stock Splits, Combinations and Dividends. If the shares of
Common Stock are subdivided or combined into a greater or smaller number of
shares of Common Stock, or if a dividend is paid on the Common Stock in shares
of Common Stock, the Conversion Price shall be proportionately reduced in case
of subdivision of shares or stock dividend or proportionately increased in the
case of combination of shares, in each such case by the ratio which the total
number of shares of Common Stock outstanding immediately after such event bears
to the total number of shares of Common Stock outstanding immediately prior to
such event.

                  D. Share Issuance. So long as this Note is outstanding, if the
Borrower shall issue or agree to issue any shares of Common Stock except for the
Excepted Issuances (as defined in the Subscription Agreement) for a
consideration less than the Conversion Price in effect at the time of such
issue, then, and thereafter successively upon each such issue, the Conversion
Price shall be reduced to such other lower issue price. For purposes of this
adjustment, the issuance of any security carrying the right to convert such
security into shares of Common Stock or of any warrant, right or option to
purchase Common Stock shall result in an adjustment to the Conversion Price upon
the issuance of the above-described security and again upon the issuance of
shares of Common Stock upon exercise of such conversion or purchase rights if
such issuance is at a price lower than the then applicable Conversion Price. The
reduction of the Conversion Price described in this paragraph is in addition to
other rights of the Holder described in this Note and the Subscription
Agreement.

            (d) Whenever the Conversion Price is adjusted pursuant to Section
2.1(c) above, the Borrower shall promptly mail to the Holder a notice setting
forth the Conversion Price after such adjustment and setting forth a statement
of the facts requiring such adjustment.

            (e) During the period the conversion right exists, Borrower will
reserve from its authorized and unissued Common Stock a sufficient number of
shares to provide for the issuance of Common Stock issuable upon the full
conversion of this Note. Borrower represents that upon issuance, such shares
will be duly and validly issued, fully paid and non-assessable. Borrower agrees
that its issuance of this Note shall constitute full authority to its officers,
agents, and transfer agents who are charged with the duty of executing and
issuing stock certificates to execute and issue the necessary certificates for
shares of Common Stock upon the conversion of this Note.

      2.2 Method of Conversion. This Note may be converted by the Holder in
whole or in part as described in Section 2.1(a) hereof and the Subscription
Agreement. Upon partial conversion of this Note, a new Note containing the same
date and provisions of this Note shall, at the request of the Holder, be issued
by the Borrower to the Holder for the principal balance of this Note and
interest which shall not have been converted or paid.

      2.3 Maximum Conversion. The Holder shall not be entitled to convert on a
Conversion Date that amount of the Note in connection with that number of shares
of Common Stock which would be in excess of the sum of (i) the number of shares
of Common Stock beneficially owned by the Holder and its affiliates on a
Conversion Date, (ii) any Common Stock issuable in connection with the
unconverted portion of the Note, and (iii) the number of shares of Common Stock
issuable upon the conversion of the Note with respect to which the determination
of this provision is being made on a Conversion Date, which would result in
beneficial ownership by the Holder and its affiliates of more than 4.99% of the
outstanding shares of Common Stock of the Borrower on such Conversion Date. For
the purposes of the provision to the immediately preceding sentence, beneficial
ownership shall be determined in accordance with Section 13(d) of the Securities
Exchange Act of 1934, as amended, and Regulation 13d-3 thereunder. Subject to
the foregoing, the Holder shall not be limited to aggregate conversions of only
4.99% and aggregate conversion by the Holder may exceed 4.99%. The Holder shall
have the authority and obligation to determine whether the restriction contained
in this Section 2.3 will limit any conversion hereunder and to the extent that
the Holder determines that the limitation contained in this Section applies, the
determination of which portion of the Notes are convertible shall be the
responsibility and obligation of the Holder. The Holder may waive the conversion
limitation described in this Section 2.3, in whole or in part, upon and
effective after 61 days prior written notice to the Borrower. The Holder may
allocate decide whether to convert a Note or exercise Warrants to achieve an
actual 4.99% ownership position.

<PAGE>

      2.4. Optional Redemption of Principal Amount. Provided an Event of Default
has not occurred, whether or not such Event of Default has been cured, the
Borrower will have the option of prepaying the outstanding Principal Amount
("Optional Redemption"), in whole or in part. If the Borrower elects to exercise
the Optional Redemption for the first thirty (30) days after the Closing Date,
the Borrower shall pay to the Holder a sum of money equal to one hundred and
twenty percent (120%) of the Principal Amount to be redeemed. If the Borrower
elects to exercise the Optional Redemption from the 31st day after the Closing
Date up to and including the 60th day after the Closing Date, the Borrower shall
pay 125% of the Principal Amount to be redeemed and thereafter 130% of the
Principal Amount to be redeemed. The Optional Redemption shall be paid together
with accrued but unpaid interest thereon and any and all other sums due, accrued
or payable to the Holder arising under this Note or any Transaction Document
through the Redemption Payment Date as defined below (the "Redemption Amount").
Borrower's election to exercise its right to prepay must be by notice in writing
("Notice of Redemption"). The Notice of Redemption shall specify the date for
such Optional Redemption (the "Redemption Payment Date"), which date shall be
thirty (30) business days after the date of the Notice of Redemption (the
"Redemption Period"). A Notice of Redemption shall not be effective with respect
to any portion of the Principal Amount for which the Holder has a pending
election to convert pursuant to Section 2.1, or for conversions initiated or
made by the Holder pursuant to Section 2.1 during the Redemption Period. On the
Redemption Payment Date, the Redemption Amount, less any portion of the
Redemption Amount against which the Holder has exercised its rights pursuant to
Section 2.1, shall be paid in good funds to the Holder. In the event the
Borrower fails to pay the Redemption Amount on the Redemption Payment Date as
set forth herein, then (i) such Notice of Redemption will be null and void, (ii)
Borrower will have no right to deliver another Notice of Redemption, and (iii)
Borrower's failure may be deemed by Holder to be a non-curable Event of Default.

                                   ARTICLE III

                                EVENT OF DEFAULT

      The occurrence of any of the following events of default ("Event of
Default") shall, at the option of the Holder hereof, make all sums of principal
and interest then remaining unpaid hereon and all other amounts payable
hereunder immediately due and payable, upon demand, without presentment, or
grace period, all of which hereby are expressly waived, except as set forth
below:

<PAGE>

      3.1 Failure to Pay Principal or Interest. The Borrower fails to pay any
installment of principal, interest or other sum due under this Note when due and
such failure continues for a period of ten (10) business days after the due
date.

      3.2 Breach of Covenant. The Borrower breaches any material covenant or
other term or condition of the Subscription Agreement or this Note in any
material respect and such breach, if subject to cure, continues for a period of
ten (10) business days after written notice to the Borrower from the Holder.

      3.3 Breach of Representations and Warranties. Any material representation
or warranty of the Borrower made herein, in the Subscription Agreement, or in
any agreement, statement or certificate given in writing pursuant hereto or in
connection therewith shall be false or misleading in any material respect as of
the date made and the Closing Date.

      3.4 Receiver or Trustee. The Borrower shall make an assignment for the
benefit of creditors, or apply for or consent to the appointment of a receiver
or trustee for it or for a substantial part of its property or business; or such
a receiver or trustee shall otherwise be appointed without the consent of the
Borrower is not dismissed within sixty (60) days of appointment.

      3.5 Judgments. Any money judgment, writ or similar final process shall be
entered or filed against Borrower or any of its property or other assets for
more than $150,000, and shall remain unvacated, unbonded or unstayed for a
period of forty-five (45) days.

      3.6 Bankruptcy. Bankruptcy, insolvency, reorganization or liquidation
proceedings or other proceedings or relief under any bankruptcy law or any law,
or the issuance of any notice in relation to such event, for the relief of
debtors shall be instituted by or against the Borrower and if instituted against
Borrower are not dismissed within forty-five (45) days of initiation.

      3.7 Delisting. Delisting of the Common Stock from any Principal Market;
failure to comply with the requirements for continued listing on a Principal
Market for a period of five consecutive trading days; or notification from any
Principal Market that the Borrower is not in compliance with the conditions for
such continued listing on such Principal Market.

      3.8 Non-Payment. A default by the Borrower under any one or more
obligations in an aggregate monetary amount in excess of $150,000 for more than
twenty days after the due date, unless the Borrower is contesting the validity
of such obligation in good faith.

      3.9 Stop Trade. An SEC or judicial stop trade order or Principal Market
trading suspension that lasts for five or more consecutive trading days.

      3.10 Failure to Deliver Common Stock or Replacement Note. Borrower's
failure to timely deliver Common Stock to the Holder pursuant to and in the form
required by this Note and Sections 7 and 11 of the Subscription Agreement, or,
if required, a replacement Note.

      3.11 Non-Registration Event. The occurrence of a Non-Registration Event as
described in Section 11.4 of the Subscription Agreement.

<PAGE>

      3.12 Reservation Default. Failure by the Borrower to have reserved for
issuance upon conversion of the Note the amount of Common stock as set forth in
this Note and the Subscription Agreement.

      3.13 Cross Default. A default by the Borrower of a material term,
covenant, warranty or undertaking of any other agreement to which the Borrower
and Holder are parties, or the occurrence of a material event of default under
any such other agreement which is not cured after any required notice and/or
cure period.

                                   ARTICLE IV

                                SECURITY INTEREST

      4. Security Interest/Waiver of Automatic Stay. This Note is secured by a
security interest granted to the Collateral Agent for the benefit of the Holder
pursuant to a Security Agreement, as delivered by Borrower to Holder. The
Borrower acknowledges and agrees that should a proceeding under any bankruptcy
or insolvency law be commenced by or against the Borrower, or if any of the
Collateral (as defined in the Security Agreement) should become the subject of
any bankruptcy or insolvency proceeding, then the Holder should be entitled to,
among other relief to which the Holder may be entitled under the Transaction
Documents and any other agreement to which the Borrower and Holder are parties
(collectively, "Loan Documents") and/or applicable law, an order from the court
granting immediate relief from the automatic stay pursuant to 11 U.S.C. Section
362 to permit the Holder to exercise all of its rights and remedies pursuant to
the Loan Documents and/or applicable law. THE BORROWER EXPRESSLY WAIVES THE
BENEFIT OF THE AUTOMATIC STAY IMPOSED BY 11 U.S.C. SECTION 362. FURTHERMORE, THE
BORROWER EXPRESSLY ACKNOWLEDGES AND AGREES THAT NEITHER 11 U.S.C. SECTION 362
NOR ANY OTHER SECTION OF THE BANKRUPTCY CODE OR OTHER STATUTE OR RULE
(INCLUDING, WITHOUT LIMITATION, 11 U.S.C. SECTION 105) SHALL STAY, INTERDICT,
CONDITION, REDUCE OR INHIBIT IN ANY WAY THE ABILITY OF THE HOLDER TO ENFORCE ANY
OF ITS RIGHTS AND REMEDIES UNDER THE LOAN DOCUMENTS AND/OR APPLICABLE LAW. The
Borrower hereby consents to any motion for relief from stay that may be filed by
the Holder in any bankruptcy or insolvency proceeding initiated by or against
the Borrower and, further, agrees not to file any opposition to any motion for
relief from stay filed by the Holder. The Borrower represents, acknowledges and
agrees that this provision is a specific and material aspect of the Loan
Documents, and that the Holder would not agree to the terms of the Loan
Documents if this waiver were not a part of this Note. The Borrower further
represents, acknowledges and agrees that this waiver is knowingly, intelligently
and voluntarily made, that neither the Holder nor any person acting on behalf of
the Holder has made any representations to induce this waiver, that the Borrower
has been represented (or has had the opportunity to he represented) in the
signing of this Note and the Loan Documents and in the making of this waiver by
independent legal counsel selected by the Borrower and that the Borrower has
discussed this waiver with counsel.

                                    ARTICLE V

                                  MISCELLANEOUS

      5.1 Failure or Indulgence Not Waiver. No failure or delay on the part of
Holder hereof in the exercise of any power, right or privilege hereunder shall
operate as a waiver thereof, nor shall any single or partial exercise of any
such power, right or privilege preclude other or further exercise thereof or of
any other right, power or privilege. All rights and remedies existing hereunder
are cumulative to, and not exclusive of, any rights or remedies otherwise
available.

<PAGE>

      5.2 Notices. All notices, demands, requests, consents, approvals, and
other communications required or permitted hereunder shall be in writing and,
unless otherwise specified herein, shall be (i) personally served, (ii)
deposited in the mail, registered or certified, return receipt requested,
postage prepaid, (iii) delivered by reputable air courier service with charges
prepaid, or (iv) transmitted by hand delivery, telegram, or facsimile, addressed
as set forth below or to such other address as such party shall have specified
most recently by written notice. Any notice or other communication required or
permitted to be given hereunder shall be deemed effective (a) upon hand delivery
or delivery by facsimile, with accurate confirmation generated by the
transmitting facsimile machine, at the address or number designated below (if
delivered on a business day during normal business hours where such notice is to
be received), or the first business day following such delivery (if delivered
other than on a business day during normal business hours where such notice is
to be received) or (b) on the second business day following the date of mailing
by express courier service, fully prepaid, addressed to such address, or upon
actual receipt of such mailing, whichever shall first occur. The addresses for
such communications shall be: (i) if to the Borrower to: Addison-Davis
Diagnostics, Inc., 143 Triumfo Canyon Road, Suite 104, Westlake Village, CA
91361, Attn: Fred De Luca, Secretary and Chairman, facsimile: (805) 494-3213,
with an additional copy by telecopier only to: Sichenzia Ross Friedman Ference
LLP, 1065 Avenue of Americas, New York, NY 10018, Attn: Darrin M. Ocasio, Esq.,
telecopier: (212) 930-9725, and (ii) if to the Holder, to the name, address and
telecopy number set forth on the front page of this Note, with a copy by
telecopier only to Grushko & Mittman, P.C., 551 Fifth Avenue, Suite 1601, New
York, New York 10176, telecopier number: (212) 697-3575.

      5.3 Amendment Provision. The term "Note" and all reference thereto, as
used throughout this instrument, shall mean this instrument as originally
executed, or if later amended or supplemented, then as so amended or
supplemented.

      5.4 Assignability. The obligations of Borrower under this Note are not
assignable without the consent of the Holder. This Note shall be binding upon
the Borrower and its successors and assigns, and shall inure to the benefit of
the Holder and its successors and assigns.

      5.5 Cost of Collection. If default is made in the payment of this Note,
Borrower shall pay the Holder hereof reasonable costs of collection, including
reasonable attorneys' fees.

      5.6 Governing Law. This Note shall be governed by and construed in
accordance with the laws of the State of New York. Any action brought by either
party against the other concerning the transactions contemplated by this
Agreement shall be brought only in the civil or state courts of New York or in
the federal courts located in the State and county of New York. Both parties and
the individual signing this Agreement on behalf of the Borrower agree to submit
to the jurisdiction of such courts. The prevailing party shall be entitled to
recover from the other party its reasonable attorney's fees and costs.

      5.7 Maximum Payments. Nothing contained herein shall be deemed to
establish or require the payment of a rate of interest or other charges in
excess of the maximum permitted by applicable law. In the event that the rate of
interest required to be paid or other charges hereunder exceed the maximum
permitted by such law, any payments in excess of such maximum shall be credited
against amounts owed by the Borrower to the Holder and thus refunded to the
Borrower.

<PAGE>

      5.8 Shareholder Status. The Holder shall not have rights as a shareholder
of the Borrower with respect to unconverted portions of this Note. However, the
Holder will have all the rights of a shareholder of the Borrower with respect to
the shares of Common Stock to be received by Holder after delivery by the Holder
of a Conversion Notice to the Borrower.

IN WITNESS WHEREOF, Borrower has caused this Note to be signed in its name by an
authorized officer as of the 23rd day of December, 2005.

                         ADDISON-DAVIS DIAGNOSTICS, INC.

                         By: /s/ Charles Miseroy
                             ------------------------------
                             Name: Charles Miseroy
                             Title: Chief Executive Officer

WITNESS:

--------------------------------------

<PAGE>

                              NOTICE OF CONVERSION

(To be executed by the Registered Holder in order to convert the Note)

      The undersigned hereby elects to convert $_________ of the principal and
$_________ of the interest due on the Note issued by Addison-Davis Diagnostics,
Inc. on December __, 2005 into Shares of Common Stock of Addison-Davis
Diagnostics, Inc. (the "Borrower") according to the conditions set forth in such
Note, as of the date written below.

Date of Conversion:_____________________________________________________________

Conversion Price:_______________________________________________________________

Shares To Be Delivered:_________________________________________________________

Signature:______________________________________________________________________

Print Name:_____________________________________________________________________

Address:________________________________________________________________________EXHIBIT 10.6

AMENDMENT TO DECEMBER 23, 2005 ORIGINAL ISSUE DISCOUNT SECURED CONVERTIBLE NOTES
TRANSACTION DOCUMENTS AGREEMENT

      Agreement made this 11th day of January, 2006 ("Amendment") among
Addison-Davis Diagnostics, Inc., a Delaware corporation (the "Company"), and the
signators hereto who are Subscribers under a certain Subscription Agreement with
the Company dated December 23, 2005 ("Subscribers").

      For good and valuable mutual consideration, receipt of which is hereby
acknowledged, the parties hereto agree as follows:

      1. All capitalized terms herein shall have the meanings ascribed to them
in the Transaction Documents (as defined in the Subscription Agreement).

      2. The Company and the Subscribers hereby agree to amend the Transaction
Documents to reflect the addition of Osher Capital Inc. as Subscriber ("New
Subscriber") in connection with the additional Purchase Price ("Additional
Purchase Price") to be paid by New Subscriber as set forth on Schedule A hereto.
Purchase Price shall mean the aggregate of the Purchase Price in connection with
the December 23, 2005 Closing Date and the Additional Purchase Price.

      3. The Company and Subscriber hereby agree to waive any disproportionality
between the Purchase Price of the December 23, 2005 Closing Date and the
Additional Purchase Price.

      4. Subscribers further agree to accelerate a funding of an aggregate of
$60,000 of the Third Closing Purchase Price in the amounts set forth on the
signature page hereto to be included in the Second Closing.

      5. The Second Closing shall take place on or before January 15, 2006 (the
"Second Closing Date") in connection with the Additional Purchase Price and the
Notes and Warrants issuable in connection therewith, upon satisfaction of all
conditions to Closing set forth in the Transaction Documents and in this
Amendment. The amount of the Additional Purchase Price and all documents to be
delivered hereunder will be deposited and held with the Escrow Agent and
released pursuant to the Escrow Agreement except that the Escrowed Payment shall
not be released until immediately following the filing of the Registration
Statement ("Release Date"). Ten Thousand Dollars ($10,000) of the Purchase Price
shall be released to Sichenzia Ross Friedman Ference LLP for legal fees in
connection with the filing of the Registration Statement. If the Registration
Statement is not timely filed by the Filing Date as described in the
Subscription Agreement, this Amendment shall be null and void at the option of a
majority of the Subscribers and New Subscriber compromising the Additional
Price. (For this purpose, majority shall mean 66% of the Subscribers and New
Subscriber compromising the Additional Purchase Price). The Notes and Warrants
to be delivered on the Second Closing Date are included in the definition of
"Securities" in the Subscription Agreement.

      6. All the representations, warranties and undertakings made by the
Company in the Transaction Documents as of the Closing Date are hereby made by
the Company as of the Second Closing Date, as if such representations,
warranties and undertakings were also made and given on the Second Closing Date.

<PAGE>

      7. All the representations, warranties and undertakings made by the
Subscribers contained in the Transaction Documents as of the Closing Date are
hereby made by the Subscribers and New Subscriber as of the Second Closing Date,
as if such representations, warranties and undertakings were also made and given
on the Second Closing Date.

      8. The New Subscriber acknowledges and agrees that by signing this
Amendment, it will be bound by all of the terms and conditions of the
Transaction Documents.

      9. All of the covenants and conditions set forth in the Subscription
Agreement are hereby adopted and renewed by the Company as of and for the Second
Closing Date.

      10. All of the covenants and conditions set forth in the Subscription
Agreement are hereby adopted and renewed by the Subscribers as of and for the
Second Closing Date.

      11. All of the terms and conditions described in Section 2 of the
Subscription Agreement in reference to the Second and Third Closing shall apply
to the Second Closing, as if such representations and warranties were made and
given on all such dates.

      12. On or before the Second Closing Date, the Company will deliver to the
Subscriber and New Subscriber, Notes, and Warrants issued as of the Second
Closing Date in the amounts set forth on Schedule A hereto in connection with
the Additional Purchase Price which the Subscriber and New Subscriber will
deposit with the Escrow Agent on or before the Second Closing Date.

      13. The Maturity Date of the Notes to be issued on the Second Closing Date
will be the same as the Maturity Date of the Notes issued on the Closing Date.

      14. The Warrants to be issued on the Second Closing Date will be identical
to the Warrants issued on the Closing Date except as to the Issue Date and
Expiration Date.

      15. On or before the Second Closing Date, the Company will deliver to the
Subscribers and New Subscribers the legal opinion described in Section 6 of the
Subscription Agreement in relation to the Second Closing, Additional Purchase
Price, Notes, and Warrants to be delivered on the Second Closing Date, which
opinion will be substantively identical to the legal opinion delivered in
connection with the Closing.

      16. The attorney for the Subscriber and New Subscriber will receive
additional Legal Fees from the Company of $2,500 which will be payable on the
Release Date out of the Escrowed Payment (as defined in the Escrow Agreement).

      17. The signators hereto acknowledge and agree that the Security Agreement
executed by the Company and Subscriber relate to the Additional Purchase Price
as if such Additional Purchase Price had been paid and released to the Company
on the December 23, 2005 Closing Date and shall also include the New Subscriber
as parties to those agreements as if such New Subscriber had been parties to
those agreements as of the December 23, 2005 Closing Date.

      18. The undersigned waive the rights granted to them pursuant to Section
12(a) (Right of First Refusal), Section 12(b) (Offering Restrictions), and
Section 12(c) (Favored Nation Provision) of the Subscription Agreement only to
the extent such rights relate to the aggregate investment of $12,000 by the New
Subscriber.

<PAGE>

      19. The undersigned consent to the amendment of all Schedules, Exhibits
and documents including but not limited to the Security Agreement to include the
New Subscriber as a party thereto and authorize the Escrow Agent to make
additional filings at the discretion of the Escrow Agent to memorialize the
security interest to be granted to the New Subscriber

      20. All other terms of the Transaction Documents shall remain in full
force and effect and govern this Agreement.

      IN WITNESS WHEREOF, the undersigned have executed and delivered this
Amendment as of the date first written above.

"COMPANY"                                   "THE ESCROW AGENT"
ADDISON-DAVIS DIAGNOSTICS, INC.             GRUSHKO & MITTMAN, P.C.
a Delaware corporation

By: /s/ Charles Miseroy
    ------------------------
Its: Chief Executive Officer

                                 "SUBSCRIBERS":

--------------------------------------      ------------------------------------
ALPHA CAPITAL AKTIENGESELLSCHAFT            OSHER CAPITAL, INC.

SCHEDULE A TO AMENDMENT

<TABLE>
<CAPTION>
------------------------------------------ ------------------- --------------------- ------------------ -------------------
               SUBSCRIBER                  INITIAL CLOSING     ADDITIONAL PURCHASE   SECOND CLOSING     PAYMENT AFTER
                                           PURCHASE PRICE      PRICE                 PURCHASE PRICE     ORIGINAL ISSUE
------------------------------------------ ------------------- --------------------- ------------------ -------------------
<S>                                        <C>                 <C>                   <C>                <C>
ALPHA CAPITAL AKTIENGESELLSCHAFT           $132,000.00         -0-                   $120,000.00        $100,000.00
Pradafant 7
9490 Furstentums
Vaduz, Lichtenstein
Fax: 011-42-32323196
------------------------------------------ ------------------- --------------------- ------------------ -------------------
OSHER CAPITAL INC.                         -0-                 $12,000.00            -0-                $10,000.00
5 Sansberry Lane
Spring Valley, NY 10977
Fax: (917) 591-3401
------------------------------------------ ------------------- --------------------- ------------------ -------------------
</TABLE>

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00097-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00097-of-00352.parquet"}]]