Document:

AMENDMENT 1 TO
                         EXECUTIVE EMPLOYMENT AGREEMENT
                                OF March 31, 2004

      THIS  AMENDMENT  I TO  EXECUTIVE  EMPLOYMENT  AGREEMENT  OF March 31, 2004
("Amendment" and "Employment Agreement", respectively), is made and entered into
as of the 10th day of September,  2004, by and between Nanobac  Pharmaceuticals,
Inc., and Neva  Ciftcioglu,  PhD, an individual  (the "Company" and  "Employee",
respectively, and "the Parties", collectively).

      WITNESSETH:   WHEREAS,  the  Parties  have  entered  into  the  Employment
Agreement dated March 31, 2004; and

      WHEREAS,  the Parties  wish to amend the  Employment  Agreement to clarify
issues related to assignment of intellectual property and compensation.

      NOW,  THEREFORE,  in consideration  of the premises,  the mutual promises,
covenants  and  conditions  herein  contained  and for other  good and  valuable
considerations,  the receipt and  sufficiency of which are hereby  acknowledged,
the parties hereto intending to be legally bound hereby agree as follows:

I.    The Parties hereby affirm  Paragraph 5 of the Employment  Agreement,  such
paragraph specifying the compensation of Employee,  except that compensation and
benefits shall commence on October 1,2004 and shall continue for five years from
that date and  Employee's  initial  signing  bonus  shall be paid by October 10,
2004.

2.    The  Parties  agree  that  Patent  Assignment  Agreement  Addendum  of the
Employment Agreement is hereby AMENDED.

3.    The Parties agree that upon execution of this Amendment,  the Parties will
execute the AMENDED Patent Assignment Agreement attached hereto as Exhibit A and
will serve as Exhibit A to the Employment Agreement of March 31, 2004.

                                     - 1 -
<PAGE>

4.    The Parties agree that any  intellectual  property  created by Employee in
the course of her employment  under the Employment  Agreement  executed on March
31, 2004, shall be the sole and exclusive property of the Company.

      IN WITNESS  WHEREOF,  the Company and  Employee  have duly  executed  this
Amendment as of the date first above written.

NANOBAC PHARMACEUTICALS, INC.:               NEVA CIFTCIOGLU, PHD:

By:  /s/ H. B. Millican                           /s/ Neva Ciftcioglu
  -------------------------------------      -----------------------------------
Print: Brady Millican
Date:  09/09/2004                                    09/12/2004
    -----------------------------------      -----------------------------------

                                     - 2 -
<PAGE>

                   ASSIGNMENT OF KNOW-HOW AND PATENT RIGHTS

      WHEREAS,  !,  Neva  Ciftcioglu,  the  below  named  inventor  (hereinafter
referred to as  Assignor),  have made a number of  inventions,  either as a sole
inventor or a joint inventor, each of which is described at least in part in the
following patent applications or invention disclosures entitled:

                     METHODS FOR ERADICATION OF NANOBACTERIA

The joint inventor(s) being:

      Olavi Kajander

for which the following patents have issued:

      a) United States Letters Patent 6,706,290, issued on March 16, 2004; and

      WHEREAS  Assignor  made such  inventions  and agreed  under an  employment
agreement  (hereinafter referred to as the Employment Agreement) effective March
31, 2004 with Nanobac Pharmaceuticals,  Inc., a Florida corporation,  whose post
office address is 2727 West Martin Luther King, Suite 850, Tampa, Florida 33607,
(hereinafter referred to along with its successors and assigns as Assignee),  to
assign such inventions;

      AND WHEREAS, Assignee is desirous of securing the entire right, title, and
interest in all countries  throughout the world,  and in and to such  inventions
and to any applications for United States Letters Patent on these inventions and
any letters Patent issued from these applications:

      NOW,  THEREFORE,  be it known that, for and in consideration of the sum of
one dollar  ($1.00) in hand paid and other good and valuable  consideration  the
receipt of which from Assignee,  is hereby acknowledged,  Assignor,  does hereby
sell, assign,  transfer, and set over unto Assignee my entire rights, title, and
interests  in and to  these  inventions  and  any  corresponding  patent  rights
(including all applications,  and all divisions,  and continuations thereof, all
Letters  Patents of the United  States  which may be  granted  thereon,  and all
reissues  thereof,  and all  rights  to  claim  priority  on the  basis  of such
application,  and all  applications  for Letters  Patent which may  hereafter be
filed for this  invention in any foreign  country and all Letters  Patents which
may be granted on this  invention in any foreign  country,  and all  extensions,
renewals,   and  reissues  thereof).   Assignor   authorizes  and  requests  the
Commissioner  of Patents and Trademarks of the United States and any official of
any  foreign  country  whose  duty it is to issue  patents  on  applications  as
described above, to issue all Letters Patent for these inventions to Assignee in
accordance with the terms of this Assignment;

                                  -- 1 of 2 --

                                                                    Assignor ___
                                                                    Assignee ___

<PAGE>

                   ASSIGNMENT OF KNOW-HOW AND PATENT RIGHTS

      AND,  ASSIGNOR  HEREBY  covenants that I have the full right to convey the
rights,  title, and interests  assigned by this Assignment,  and that I have not
executed and will not execute any agreement in conflict with this Assignment;

      AND ASSIGNOR  HEREBY  further  covenants  and agrees that I will,  without
further  consideration,   communicate  with  Assignee  any  facts  known  to  me
respecting these inventions,  testify in any legal  proceeding,  sign all lawful
papers when called upon to do so, or execute and deliver any and all papers that
may be  necessary  or  desirable  to perfect the title to these  inventions  for
Assignee  (including  executing  all  divisional,   continuation,   and  reissue
applications,  making all rightful oaths and generally doing everything possible
to aid  Assignee  to obtain  and  enforce  proper  patent  protection  for these
inventions in the United  States and any foreign  country,  it being  understood
that any expense  incident  to the  execution  of such papers  shall be borne by
Assignee).

      AND ASSIGNEE  HEREBY AGREES to assign back to Assignor any rights assigned
hereunder,  if Assignee fails to timely pay all  compensation due Assignor under
Assignor's Employment Agreement with Assignee.

      IN TESTIMONY  WHEREOF,  Assignor  signs and delivers  this  Assignment  to
Assignee.

     /s/ Neva Ciftcioglu                           Date:    09/12/2004
------------------------------------                   ------------------------
Neva Ciftcioglu, PhD
Of
18800 Egret Bay Blvd, Suite 114
Houston, TX 77058

Turkey
[Country of Citizenship]

     /s/ H. B. Millican                             Date:    09/09/2004
------------------------------------                    -----------------------
H. Brady Millican
Vice President, COO
Nanobac Pharmaceuticals, Inc.

                                  -- 2 of 2 --SUBSCRIPTION AGREEMENT

               THIS SUBSCRIPTION AGREEMENT (this "Agreement") is made and
entered into as of August 13, 2004, by and between Nanobac Pharmaceuticals,
Incorporated, a Florida corporation (the "Company"), and The Nutmeg Group,
L.L.C., a US Virgin Islands limited liability company (the "Purchaser").

      1.    Subscription. Subject to the terms and conditions contained herein,
the Purchaser hereby agrees to purchase from the Company, and the Company hereby
agrees to issue and sell to the Purchaser, a certain number of shares of the
Company's Common Stock (the "Common Stock"), and warrants to purchase additional
shares of Common Stock (the Common Stock and warrants referred to as the
"Securities"), for an aggregate purchase price of up to $1,000,000 (the
"Purchase Price"). The number of shares issuable to Purchaser (the "Applicable
Number") will equal the Purchase Price, divided by the lesser of:

      (a)   $0.12, or

      (b)   fifty-two percent (52%) of the average closing bid price for Common
Stock on the five trading days prior to the date on which the registration
statement (as described in the Registration Rights Agreement) is declared
effective

      (the lesser of (a) and (b) being hereinafter referred to as the "Fixed
Price").

      Purchaser will be issued Warrants (hereinafter "Warrants") exercisable
into such number of shares of Common Stock as is equal to 100% of the Purchase
Price paid by Purchaser, divided by the Fixed Price. The Common Stock into which
the Warrants are exercisable will have piggyback registration rights, and the
Warrants will be transferable. Unexercised Warrants will expire December 31,
2008 ("Warrant Expiration Date"). 50% of the Warrants will be exercisable into
Common Stock at a per share price equal to 110% of the lesser of (a) $0.12; or
(b) fifty-two percent (52%) of the average closing bid price for Common Stock on
the five trading days immediately prior to the filing with the Securities and
Exchange Commission of the Registration Statement. The remaining 50% of the
Warrants will be exercisable into Common Stock at a per share price equal to
150% of the lesser of (a) $0.12; or (b) fifty-two percent (52%) of the average
closing bid price for Common Stock on the five trading days immediately prior to
the filing with the Securities and Exchange Commission of the Registration
Statement.

      The $1,000,000 Purchase Price will be payable by Purchaser, in two
traunches. The first traunche will be in the amount of $500,000 and shall occur
no later than August 13, 2004. The second traunche will be an amount equal to
$500,000 and shall occur within 5 days of the date on which the registration
statement registering the Securities is declared effective.

      The Purchaser will receive at each Closing a flat non-accountable expense
allowance of $10,000 to cover legal, escrow fees and miscellaneous costs. At the
election of the Purchaser, or its designees, any or all of the foregoing
compensation and expense allowances can be taken in kind, pursuant to the same
terms and conditions as that of an investment herein, for a like amount.

<PAGE>

      The Purchaser or its designee shall also be entitled to a commission of 5%
of any and all amounts received, directly or indirectly, by the Company and/or
its principals as a consequence of a merger, license or any other similar
arrangement or remuneration as a consequence of the efforts of Nutmeg or its
designee or agent. All references to the "Company" shall include associates, and
any individual, corporation, organization, firm or company, of which the Company
is a member, employee, principal, party to, or from which such it would
otherwise benefit financially, directly or indirectly.

            Closing. The closing (the "Closing") of the purchase and sale of the
Securities shall take place at the offices of the Company, the Company will
deliver to the Purchaser certificates for the Shares and the warrant agreement
against payment to the Company of the Purchase Price by wire transfer or other
acceptable consideration designated by the Company.

            Conditions to Obligations of the Purchaser. The Purchaser's
obligation to purchase the Securities at the Closing is subject to the
fulfillment (or waiver by the Purchaser), at or prior to the Closing, of each of
the following conditions:

            Accuracy of the Company's Representations and Warranties. The
representations and warranties of the Company contained in this Agreement shall
be true and correct in all material respects at the time of the Closing, except
as such representations and warranties are affected by the consummation of the
transactions contemplated by this Agreement.

            Performance by the Company. The Company shall have duly performed
and complied in all material respects with all agreements and conditions
contained in this Agreement and required to be performed or complied with by the
Company at or prior to the Closing.

            Nonfulfillment of Conditions. If any of the conditions specified in
Section 3 shall not have been fulfilled at or prior to the Closing, the
Purchaser shall be relieved of all further obligations under this Agreement,
without thereby waiving any other rights the Purchaser may have by reason of
such nonfulfillment.

            Maximum Exercise. At any point in time, the Purchaser shall not be
entitled to receive shares of common stock if such issuance would result in
beneficial ownership by the Purchaser and its affiliates of more than 4.99% of
the outstanding shares of common stock of the Company on such issue date,
including:

            (i) the number of shares of common stock beneficially owned by the
Purchaser and its affiliates, and

            (ii) the number of shares of common stock issuable upon the exercise
or conversion of securities owned.

            For the purposes of this provision as set forth in the immediately
preceding sentence, beneficial ownership shall be determined in accordance with
Section 13(d) of the Securities Exchange Act of 1934, as amended, and Regulation
13d-3 thereunder. Subject to the foregoing, the Purchaser shall not be limited
to aggregate common stock issuances of only 4.99% and aggregate common stock
issuances may exceed 4.99%. The Purchaser may void the issuance limitation
described in this Section upon 61 days prior written notice to the Company. The
Purchaser may allocate which of the equity of the Company deemed beneficially
owned by the Purchaser shall be included in the 4.99% amount described above and
which shall be allocated to the excess above 4.99%.

<PAGE>

            Conditions to Obligations of the Company. The obligations of the
Company to issue and sell the Securities to the Purchaser at the Closing shall
be subject to the fulfillment (or waiver by the Company), at or prior to the
Closing, of each of the following conditions:

            1.1   Accuracy of the Purchaser's Representations and Warranties.
The representations and warranties made by the Purchaser in this Agreement shall
be true and correct in all material respects when made and at the time of the
Closing.

            1.2   Performance by the Purchaser. The Purchaser shall have duly
performed and complied in all material respects with all agreements and
conditions contained in this Agreement and required to be performed or complied
with by the Purchaser at or prior to the Closing, including but not limited to
payment to the Company of the Purchase Price for the Securities in immediately
available funds.

      2.    Representations and Warranties of the Company. The Company
represents and warrants to the Purchaser as follows:

            2.1   Corporate Organization and Standing. The Company is a
corporation duly organized, validly existing and in good standing under the laws
of the State of its incorporation and has all requisite corporate power and
authority to own or lease its properties and to carry on its business as
presently conducted.

            2.2   Authorization. This Agreement and the transactions
contemplated hereby have been duly authorized by all necessary corporate action
on the part of the Company. This Agreement has been duly executed and delivered
by the Company, and are the legal, valid and binding obligations of the Company,
enforceable against it in accordance with their terms.

            2.3   No Conflict or Violation. Subject to the Company obtaining
stockholder approval to increase its authorized common stock, neither the
execution and delivery of this Agreement, nor the consummation of the
transactions contemplated hereby, will (a) violate, conflict with or result in a
breach of or constitute a default under any provision of the Certificate of
Incorporation or Bylaws of the Company, (b) violate, conflict with or result in
a breach of or constitute a default under any judgment, order, decree, rule or
regulation of any court or governmental agency to which the Company is subject
or (c) violate, conflict with or result in a breach of any applicable rule or
regulation of any federal, state, local or other governmental authority.

            2.4   Stock. The Securities to be issued to the Purchaser pursuant
to this Agreement are duly authorized and, when issued and paid for in
accordance with the terms of this Agreement, will be validly issued, fully paid
and nonassessable.

<PAGE>

      3.    Representations and Warranties of the Purchaser. The Purchaser
represents and warrants to the Company that:

            3.1   Authorization. The Purchaser is a limited liability company
duly organized, validly existing and in good standing under the laws of the USVI
and has all requisite power and authority to execute and deliver this Agreement
and to subscribe for and purchase the Securities hereunder. This Agreement and
the transactions contemplated hereby and thereby have been duly authorized by
all necessary limited liability company action on the part of the Purchaser.
This Agreement has been duly executed and delivered by the Purchaser, and is the
legal, valid and binding obligations of the Purchaser, enforceable against it in
accordance with their terms.

            3.2   No Conflict or Violation. Neither the execution and delivery
of this Agreement, nor the consummation of the transactions contemplated hereby,
will (a) violate, conflict with or result in a breach of or constitute a default
under any provision of the limited liability company agreement of the Purchaser,
(b) violate, conflict with or result in a breach of or constitute a default
under any judgment, order, decree, rule or regulation of any court or
governmental agency to which the Purchaser is subject or (c) violate, conflict
with or result in a breach of any applicable rule or regulation of any federal,
state, local or other governmental authority.

            3.3   Access to Information; Investigation. The Purchaser made,
either alone or together with its advisors (if any), such independent
investigation of the Company, its management and related matters as the
Purchaser deemed to be, or such advisors (if any) have advised to be, necessary
or advisable in connection with an investment in the Securities. The Purchaser
and its advisors (if any) have received all information and data that the
Purchaser and such advisors (if any) believe to be necessary in order to reach
an informed decision as to the advisability of an investment in the Shares.

            3.4   Information Regarding the Purchaser. The Purchaser is (a) not
an "underwriter" within the meaning of the Securities Act of 1933 or otherwise,
and (b) not otherwise acting as a placement agent, broker or dealer in
connection with its acquisition of the Securities. distribution.

            3.5   Investment Intent. Such Purchaser is acquiring the Securities
as principal for its own account for investment purposes only and not with a
view to or for distributing or reselling such Securities or any part thereof,
without prejudice, however, to such Purchaser's right, subject to the provisions
of this Agreement, at all times to sell or otherwise dispose of all or any part
of such Securities pursuant to an effective registration statement under the
Securities Act or under an exemption from such registration and in compliance
with applicable federal and state securities laws. Such Purchaser is acquiring
the Securities hereunder in the ordinary course of its business. Such Purchaser
does not have any agreement or understanding, directly or indirectly, with any
Person to distribute any of the Securities.

            3.6   Purchaser Status. At the time such Purchaser was offered the
Securities, it was, and at the date hereof it is, and on each date on which it
exercises any Warrants or receives any shares of Common Stock it will be, an
"accredited investor" as defined in Rule 501(a) under the Securities Act. Such
Purchaser has not been formed solely for the purpose of acquiring the
Securities. Such Purchaser is not a registered broker-dealer under Section 15 of
the Exchange Act.

<PAGE>

            3.7   Experience of such Purchaser. Such Purchaser, either alone or
together with its representatives, has such knowledge, sophistication and
experience in business and financial matters so as to be capable of evaluating
the merits and risks of the prospective investment in the Securities, and has so
evaluated the merits and risks of such investment. Such Purchaser is able to
bear the economic risk of an investment in the Securities and, at the present
time, is able to afford a complete loss of such investment.

            3.8   General Solicitation. Such Purchaser is not purchasing the
Securities as a result of any advertisement, article, notice or other
communication regarding the Securities published in any newspaper, magazine or
similar media or broadcast over television or radio or presented at any seminar
or any other general solicitation or general advertisement.

            3.9   Reliance on Representations and Warranties of the Purchaser.
The Purchaser understands and acknowledges that the Company is relying on the
representations and warranties made by the Purchaser in this Agreement in
connection with the transactions contemplated hereby.

            3.10  Indemnification. Each party (the "Indemnifying Party") will
indemnify and hold the other parties and their directors, officers,
shareholders, partners, employees and agents (each, an "Indemnified Party")
harmless from any and all losses, liabilities, obligations, claims,
contingencies, damages, costs and expenses, including all judgments, amounts
paid in settlements, court costs and reasonable attorneys' fees and costs of
investigation that any such Indemnified Party may suffer or incur as a result of
or relating to any breach of any of the representations, warranties, covenants
or agreements made by the Indemnifying Party in this Agreement. If any action
shall be brought against any Indemnified Party in respect of which indemnity may
be sought pursuant to this Agreement, such Indemnified Party shall promptly
notify the Indemnifying Party in writing, and the Indemnifying Party shall have
the right to assume the defense thereof with counsel of its own choosing. Any
Indemnified Party shall have the right to employ separate counsel in any such
action and participate in the defense thereof, but the fees and expenses of such
counsel shall be at the expense of such Indemnified Party except to the extent
that (i) the employment thereof has been specifically authorized by the
Indemnifying Party in writing, (ii) the Indemnifying Party has failed after a
reasonable period of time to assume such defense and to employ counsel or (iii)
in such action there is, in the reasonable opinion of such separate counsel, a
material conflict on any material issue between the position of the Indemnifying
Party and the position of such Indemnified Party. The Indemnifying Party will
not be liable to any Indemnified Party under this Agreement (i) for any
settlement by an Indemnified Party effected without the Indemnifying Party's
prior written consent, which shall not be unreasonably withheld or delayed; or
(ii) to the extent, but only to the extent that a loss, claim, damage or
liability is attributable to any Indemnified Party's breach of any of the
representations, warranties, covenants or agreements made by the Purchasers in
this Agreement.

<PAGE>

      4.    Amendments and Waivers. This Agreement may be amended and the
observance of any provision hereof may be waived (either generally or in a
particular instance and either retroactively or prospectively) only with the
written consent of each party to be bound thereby. No provision of this
Agreement shall be deemed to have been waived, unless such waiver is contained
in a written notice given to the party claiming such waiver, and no such waiver
shall be deemed to be a waiver of any other or further obligation or liability
of the party or parties in whose favor the waiver was given.

      5.    Survival of Representations and Warranties. All representations and
warranties contained herein or made in writing by the Purchaser or by the
Company in connection with the transactions contemplated by this Agreement shall
survive the Closing Date and shall remain in full force and effect for three
years thereafter. All covenants and agreements contained in this Agreement shall
survive the Closing Date indefinitely until, by their respective terms, they are
no longer operative. No claims shall be made after the date on which the
applicable representation or warranty upon which such claim was based ceases to
survive pursuant to this Section; provided, however, that the expiration of any
representation or warranty under this Section shall not affect any claim made in
good faith prior to the date of such expiration.

      6     Successors and Assigns. This Agreement shall be binding upon and
inure to the benefit of and be enforceable by the respective successors and
assigns of the parties hereto.

      7.    Notices. All notices, requests, demands and other communications
given hereunder (collectively, "Notices") shall be in writing and delivered
personally or by overnight courier to the parties at the following addresses or
sent by telecopier or telex, with confirmation received, to the telecopy
specified below:

            If to the Company, at:

                     2727 W. Martin Luther King Blvd., Suite 850
                     Tampa, FL 33607

                     With copy to:

                     DARRIN M. OCASIO, ESQ.
                     SICHENZIA ROSS FRIEDMAN FERENCE LLP
                     1065 Avenue of the Americas, 21st flr.
                     New York, New York 10018
                     tel: 212-930-9700
                     fax:212-930-9725
                     dmocasio@srffllp.com

            If to the Purchaser, at:

                     Randall S. Goulding
                     The Nutmeg Group, L.L.C.
                     3366 Commercial
                     Northbrook IL 60062
                     tel: 847-291-7711
                     fax: 253-736-0134

<PAGE>

      All Notices shall be deemed delivered when actually received if delivered
personally or by overnight courier, sent by telecopier or telex (promptly
confirmed in writing), addressed as set forth above. Each of the parties shall
hereafter notify the other in accordance with this Section, of any change of
address or telecopy number to which notice is required to be mailed.

      8.    Governing Law; Enforcement. This Agreement shall be governed by and
construed and enforced in accordance with the internal laws of the State of
Illinois applicable to contracts made in that state, without giving effect to
the conflicts of laws principles thereof. The parties agree that irreparable
damage would occur in the event that any of the provisions of this Agreement
were not performed in accordance with their specific terms or were otherwise
breached. It is accordingly agreed that the parties are entitled to an
injunction or injunctions to prevent breaches of this Agreement and to enforce
specifically the terms and provisions of this Agreement in any court of the
United States located in the State of Illinois or in Illinois state court, this
being in addition to any other remedy to which they are entitled at law or in
equity. In addition, each of the parties hereto (a) consents to submit itself to
the personal jurisdiction of any federal court located in the State of Illinois
or any Illinois state court in the event any dispute arises out of this
Agreement or any of the transactions contemplated by this Agreement, (b) agrees
that it will not attempt to deny such personal jurisdiction by motion or other
request for leave from any such court and (c) agrees that it will not bring any
action relating to this Agreement or any of the transactions contemplated by
this Agreement in any court other than a federal or state court sitting in the
State of Illinois.

      9.    Disputes. The parties agree to submit any dispute arising under this
Agreement to arbitration to be held in Illinois. Arbitration shall be by a
single arbitrator experienced in the matters at issue selected by the parties in
accordance with the commercial arbitration rules of the Better Business Bureau
or the American Arbitration Association. The decision of the arbitrator shall be
final and binding as to any matter submitted to him under this Agreement. All
costs and expenses incurred in connection with such arbitration proceeding shall
be borne by the party against whom the decision is rendered.

      10.   Headings. The headings contained in this Agreement are for reference
purposes only and shall not affect in any way the meaning or interpretation of
this Agreement.

      11.   Counterparts. This Agreement may be executed in one or more
counterparts, all of which shall constitute one and the same instrument.

      12.   Entire Agreement. This Agreement and the Letter Agreement constitute
the entire agreement of the parties with respect to the subject matter hereof
and supersede all prior negotiations, agreements and understandings, whether
written or oral, of the parties.

      13.   No Third-Party Rights. This Agreement is not intended, and shall not
be construed, to create any rights in any parties other than the Company and the
Purchaser and no person shall assert any rights as third-party beneficiary
hereunder.

<PAGE>

      14.   Severability. If any term or other provision of this Agreement is
invalid, illegal or incapable of being enforced by any rule of law, or public
policy, all other conditions and provisions of this Agreement shall nevertheless
remain in full force and effect so long as the economic or legal substance of
the transactions contemplated hereby is not affected in any manner adverse to
any party. Upon such determination that any term or other provision is invalid,
illegal or incapable of being enforced, the parties hereto shall negotiate in
good faith to modify this Agreement so as to affect the original intent of the
parties as closely as possible in an acceptable manner to the end that
transactions contemplated hereby are fulfilled to the extent possible.

<PAGE>

      IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of
the date first set forth above.

                                          NANOBAC PHARMACEUTICALS, INCORPORATED

                                          By: /s/Alexander Edwards III
                                             ---------------------------
                                          Its: Director
                                              --------------------------

                                          THE NUTMEG GROUP, L.L.C.

                                          By:  /s/ Randall S. Goulding
                                             ---------------------------
                                          Its: Managing Director
                                              --------------------------

<PAGE>

                         REGISTRATION RIGHTS AGREEMENT

      THIS REGISTRATION RIGHTS AGREEMENT, dated as of August 13, 2004, between
The Nutmeg Group, L.L.C., a US Virgin Islands limited liability company
("Holder"), and Nanobac Pharmaceuticals, Incorporated, a corporation
incorporated under the laws of the State of Florida (the "Company").

      WHEREAS, simultaneously with the execution and delivery of this Agreement,
the Holder is purchasing from the Company, pursuant to a Subscription Agreement
dated the date hereof (the "Subscription Agreement"), shares of the Company's
Common Stock (the "Common Shares"), and a Class A and B Warrants exercisable to
purchase additional shares of the Company's Common Stock (terms not defined
herein shall have the meanings ascribed to them in the Subscription Agreement);
and

      WHEREAS, the Company desires to grant to the Holder the registration
rights set forth herein with respect to the shares of Common Stock issued
pursuant to the Subscription Agreement and with respect to the shares of Common
Stock issuable upon exercise of the Class A and B Warrants (the "Warrant
Shares") (hereinafter the Common Shares and the Warrant Shares shall be referred
to collectively as the "Securities" of the Company).

      NOW, THEREFORE, the parties hereto mutually agree as follows:

      Section 1. Registrable Securities. As used herein the term "Registrable
Security" means the Securities until (i) the Registration Statement has been
declared effective by the SEC, and all Securities have been disposed of pursuant
to the Registration Statement, (ii) all Securities have been sold under
circumstances under which all of the applicable conditions of Rule 144 (or any
similar provision then in force) under the Securities Act ("Rule 144") are met,
(iii) all Securities have been otherwise transferred to holders who may trade
such Securities without restriction under the Securities Act, and the Company
has delivered a new certificate or other evidence of ownership for such
Securities not bearing a restrictive legend or (iv) such time as, in the opinion
of counsel to the Company, all Securities may be sold without any time, volume
or manner limitations pursuant to Rule 144(k) (or any similar provision then in
effect) under the Securities Act. The term "Registrable Securities" means any
and/or all of the securities falling within the foregoing definition of a
"Registrable Security." In the event of any merger, reorganization,
consolidation, recapitalization or other change in corporate structure affecting
the Common Stock, such adjustment shall be deemed to be made in the definition
of "Registrable Security" as is appropriate in order to prevent any dilution or
enlargement of the rights granted pursuant to this Agreement.

      Section 2. Restrictions on Transfer. The Holder acknowledges and
understands that prior to the registration of the Securities as provided herein,
the Securities are "restricted securities" as defined in Rule 144 promulgated
under the Act. The Holder understands that no disposition or transfer of the
Securities may be made by Holder in the absence of (i) an opinion of counsel to
the Holder that such transfer may be made without registration under the
Securities Act or (ii) such registration.

<PAGE>

      With a view to making available to the Holder the benefits of Rule 144
under the Securities Act or any other similar rule or regulation of the SEC that
may at any time permit the Holder to sell securities of the Company to the
public without registration ("Rule 144"), the Company agrees to:

            (a)   comply with the provisions of paragraph (c)(1) of Rule 144;
and

            (b)   file with the SEC in a timely manner all reports and other
documents required to be filed by the Company pursuant to Section 13 or 15(d)
under the Exchange Act; and, if at any time it is not required to file such
reports but in the past had been required to or did file such reports, it will,
upon the request of any Holder, make available other information as required by,
and so long as necessary to permit sales of, its Registrable Securities pursuant
to Rule 144.

      Section 3. Registration Rights With Respect to the Securities.

            (a)   The Company will use its best efforts to (i) prepare and file
a registration statement on Form S-1, Form S-2, Form S-3 or Form SB-2 to
register a sufficient number of shares of Common Stock to accommodate a
$1,000,000 purchase of Common Stock, and to register the shares of Common Stock
into which the Warrants are exercisable into (the "Registration Statement")
within forty-five days from the date on which the Company receives from the
Holder an aggregate of $1,000,000 (the "Initial Filing Date"), and (ii) have the
registration statement declared effective within 90 days following the Initial
Filing Date, and thereafter to cause the registration statement to remain
effective through December 31, 2008, and in the case of Warrants, through the
Warrant Expiration Date. If the registration statement is not effective within
165 days from the Initial Filing Date, then the Company shall refund to Nutmeg
an amount equal to one percent (1%) of the amount invested by Nutmeg with regard
to such Closing. For each further thirty day period thereafter until the
registration statement is effective, the Company shall refund to Nutmeg an
amount equal to one percent (.5%) of the amount invested by Nutmeg with regard
to such Closing; provided however, the maximum refund to the Holder pursuant to
this section shall be ten percent (10%) of the amount invested by Nutmeg.

            (b)   The Company will maintain the Registration Statement or
post-effective amendment filed under this Section 3 hereof effective under the
Securities Act until the earlier of (i) the date that none of the Securities are
or may become issued and outstanding, (ii) the date that all of the Securities
have been sold pursuant to the Registration Statement, (iii) the date the
holders thereof receive an opinion of counsel to the Company, which counsel
shall be reasonably acceptable to the Holder, that the Securities may be sold
under the provisions of Rule 144 without limitation as to volume, (iv) all
Securities have been otherwise transferred to holders who may trade such shares
without restriction under the Securities Act, and the Company has delivered a
new certificate or other evidence of ownership for such securities not bearing a
restrictive legend, or (v) all Securities may be sold without any time, volume
or manner limitations pursuant to Rule 144(k) or any similar provision then in
effect under the Securities Act in the opinion of counsel to the Company, which
counsel shall be reasonably acceptable to the Holder (the "Effectiveness
Period").

<PAGE>

            (c)   All fees, disbursements and out-of-pocket expenses and costs
incurred by the Company in connection with the preparation and filing of the
Registration Statement under subparagraph 3(a) and in complying with applicable
securities and Blue Sky laws (including, without limitation, all attorneys' fees
of the Company) shall be borne by the Company. The Holder shall bear the cost of
underwriting and/or brokerage discounts, fees and commissions, if any,
applicable to the Securities being registered and the fees and expenses of its
counsel. The Holder and its counsel shall be provided with and shall have a
reasonable period, not to exceed three (3) Trading Days, to review the proposed
Registration Statement or any amendment thereto, prior to filing with the SEC,
and the Company shall provide each Holder with copies of any comment letters
received from the SEC with respect thereto within two (2) Trading Days of
receipt thereof. The Company shall make reasonably available for inspection by
each Holder, any underwriter participating in any disposition pursuant to the
Registration Statement, and any attorney, accountant or other agent retained by
such Holder or any such underwriter all relevant financial and other records,
pertinent corporate documents and properties of the Company and its
subsidiaries, and cause the Company's officers, directors and employees to
supply all information reasonably requested by such Holder or any such
underwriter, attorney, accountant or agent in connection with the Registration
Statement, in each case, as is customary for similar due diligence examinations;
provided, however, that all records, information and documents that are
designated in writing by the Company, in good faith, as confidential,
proprietary or containing any material non-public information shall be kept
confidential by such Holder and any such underwriter, attorney, accountant or
agent (pursuant to an appropriate confidentiality agreement in the case of any
such Holder or agent), unless such disclosure is made pursuant to judicial
process in a court proceeding (after first giving the Company an opportunity
promptly to seek a protective order or otherwise limit the scope of the
information sought to be disclosed) or is required by law, or such records,
information or documents become available to the public generally or through a
third party not in violation of an accompanying obligation of confidentiality;
and provided further that, if the foregoing inspection and information gathering
would otherwise disrupt the Company's conduct of its business, such inspection
and information gathering shall, to the maximum extent possible, be coordinated
on behalf of the Holder and the other parties entitled thereto by one firm of
counsel designated by and on behalf of the Holder and other parties. The Company
shall qualify any of the securities for sale in such states as such Holder
reasonably designates and shall furnish indemnification in the manner provided
in Section 6 hereof. However, the Company shall not be required to qualify in
any state which will require an escrow or other restriction relating to the
Company and/or its affiliates or the sellers, or which will require the Company
to qualify to do business in such state or require the Company to file therein
any general consent to service of process. The Company at its expense will
supply the Holder with copies of the Registration Statement and the prospectus
included therein and other related documents in such quantities as may be
reasonably requested by the Holder.

            (d)   The Company shall not be required by this Section 3 to include
the Holder's Securities in any Registration Statement which is to be filed if,
in the opinion of counsel for both the Holder and the Company (or, should they
not agree, in the opinion of another counsel experienced in securities law
matters acceptable to counsel for the Holder and the Company) the proposed
offering or other transfer as to which such registration is requested is exempt
from applicable federal and state securities laws and would result in all
purchasers or transferees obtaining securities which are not "restricted
securities", as defined in Rule 144 under the Securities Act.

<PAGE>

            (e)   No provision contained herein shall preclude the Company from
selling securities pursuant to any Registration Statement in which it is
required to include Securities pursuant to this Section 3. It is the
understanding of the Holder that the Company may undertake a firm commitment
underwritten public offering (the "Public Offering"). In the event that the
registration statement for the Public Offering is filed on or before the Initial
Filing Date (which may be extended to no later than thirty (30) days by the
managing underwriter of the Public Offering), then Holder agrees that in lieu of
the Registration Statement required by this Agreement, the Company may include
Holder's Registrable Securities as a selling securityholder in the Public
Offering registration statement, but not as part of the underwritten offering.
The Public Offering registration statement will be kept effective (at least as
to Holder's Registrable Securities) for the period otherwise required herein.
Holder shall agree to such "lockup" as may be required by the underwriters of
the Public Offering, provided that under no circumstances shall Holder be
required to agree to any lockup of more than 75% of its Registrable Securities
(allocated proportionately among the Common Shares and Warrant Shares), and as
to such locked-up Registrable Securities, such lock-up shall not exceed 180 days
from the effective date of the Public Offering registration statement. If the
Public Offering is abandoned, or the underwriters of the Public Offering require
a lock-up from Holder which is more severe than that set forth above, then the
Company shall again be obligated to file the Registration Statement called for
by this Agreement for Holder's benefit, and shall so file within 15 business
days of such event.

            (f)   If at any time or from time to time after the effective date
of the Registration Statement, the Company notifies the Holder in writing of the
existence of a Potential Material Event (as defined in Section 3(h) below), the
Holder shall not offer or sell any Securities or engage in any other transaction
involving or relating to Securities, from the time of the giving of notice with
respect to a Potential Material Event until such Holder receives written notice
from the Company that such Potential Material Event either has been disclosed to
the public or no longer constitutes a Potential Material Event; provided,
however, that the Company may not so suspend the right to such holders of
Securities for more than twenty (20) days in the aggregate (or such greater
period, not to exceed 90 days in the aggregate, as may be required to prepare
and file audited financial statements of a company or business acquired) during
any twelve month period, during the periods the Registration Statement is
required to be in effect. If a Potential Material Event shall occur prior to the
date the Registration Statement is filed, then the Company's obligation to file
the Registration Statement shall be delayed without penalty for not more than
twenty (20) days (or such greater period, not to exceed 90 days in the
aggregate, as may be required to prepare and file audited financial statements
of a company or business acquired). The Company must give Holder notice in
writing at least two (2) Trading Days prior to the first day of the blackout
period.

            (g)   "Potential Material Event" means any of the following: (a) the
possession by the Company of material information not ripe for disclosure in a
registration statement, as determined in good faith by the Chief Executive
Officer or the Board of Directors of the Company that disclosure of such
information in the Registration Statement would be detrimental to the business
and affairs of the Company; or (b) any material engagement or activity by the
Company which would, in the good faith determination of the Chief Executive
Officer or the Board of Directors of the Company, be adversely affected by
disclosure in a registration statement at such time, which determination shall
be accompanied by a good faith determination by the Chief Executive Officer or
the Board of Directors of the Company that the Registration Statement would be
materially misleading absent the inclusion of such information.

<PAGE>

      Section 4. Cooperation with Company. Holder will cooperate with the
Company in all respects in connection with this Agreement, including timely
supplying all information reasonably requested by the Company (which shall
include all information regarding the Holder and proposed manner of sale of the
Registrable Securities required to be disclosed in the Registration Statement)
and executing and returning all documents reasonably requested in connection
with the registration and sale of the Registrable Securities and entering into
and performing its obligations under any underwriting agreement, if the offering
is an underwritten offering, in usual and customary form, with the managing
underwriter or underwriters of such underwritten offering. Nothing in this
Agreement shall obligate the Holder to consent to be named as an underwriter in
the Registration Statement. The obligation of the Company to register the
Registrable Securities shall be absolute and unconditional as to those
Securities which the SEC will permit to be registered without naming the Holder
as an underwriter.

      Section 5. Registration Procedures. If and whenever the Company is
required by any of the provisions of this Agreement to effect the registration
of any of the Registrable Securities under the Act, the Company shall (except as
otherwise provided in this Agreement), as expeditiously as possible, subject to
the Holder's assistance and cooperation as reasonably required:

            (a)   (i) prepare and file with the SEC such amendments and
supplements to the Registration Statement and the prospectus used in connection
therewith as may be necessary to keep such registration statement effective and
to comply with the provisions of the Act with respect to the sale or other
disposition of all securities covered by such registration statement whenever
the Holder of such Registrable Securities shall desire to sell or otherwise
dispose of the same (including prospectus supplements with respect to the sales
of securities from time to time in connection with a registration statement
pursuant to Rule 415 promulgated under the Act) and (ii) take all lawful action
such that each of (A) the Registration Statement and any amendment thereto does
not, when it becomes effective, contain an untrue statement of a material fact
or omit to state a material fact required to be stated therein or necessary to
make the statements therein, not misleading and (B) the Prospectus forming part
of the Registration Statement, and any amendment or supplement thereto, does not
at any time during the Registration Period include an untrue statement of a
material fact or omit to state a material fact required to be stated therein or
necessary to make the statements therein, in light of the circumstances under
which they were made, not misleading.

            (b)   (i) prior to the filing with the SEC of any Registration
Statement (including any amendments thereto) and the distribution or delivery of
any prospectus (including any supplements thereto), provide draft copies thereof
to the Holder and reflect in such documents all such comments as the Holder (and
its counsel) reasonably may propose respecting the Selling Shareholders and Plan
of Distribution sections (or equivalents) and (ii) furnish to each Holder such
numbers of copies of a prospectus including a preliminary prospectus or any
amendment or supplement to any prospectus, as applicable, in conformity with the
requirements of the Act, and such other documents, as Holder may reasonably
request in order to facilitate the public sale or other disposition of the
securities owned by such Holder;

<PAGE>

            (c)   register and qualify the Registrable Securities covered by the
Registration Statement under such other securities or blue sky laws of such
jurisdictions as the Holder shall reasonably request (subject to the limitations
set forth in Section 3(d) above), and do any and all other acts and things which
may be necessary or advisable to enable Holder to consummate the public sale or
other disposition in such jurisdiction of the securities owned by Holder, except
that the Company shall not for any such purpose be required to qualify to do
business as a foreign corporation in any jurisdiction wherein it is not so
qualified or to file therein any general consent to service of process;

            (d)   list such Registrable Securities on the Pink Sheets, OTC
Bulletin Board, if required, or the American Stock Exchange, other national
securities exchange, the NASDAQ National Market or the NASDAQ Small-Cap Market,
on which the Common Stock of the Company is then listed, if the listing of such
Registrable Securities is then permitted under the rules of such exchange or
NASDAQ;

            (e)   notify each Holder of Registrable Securities covered by the
Registration Statement, at any time when a prospectus relating thereto covered
by the Registration Statement is required to be delivered under the Act, of the
happening of any event of which it has knowledge as a result of which the
prospectus included in the Registration Statement, as then in effect, includes
an untrue statement of a material fact or omits to state a material fact
required to be stated therein or necessary to make the statements therein not
misleading in the light of the circumstances then existing, and the Company
shall prepare and file a curative amendment under Section 5(a) as quickly as
commercially possible;

            (f)   as promptly as practicable after becoming aware of such event,
notify each Holder who holds Registrable Securities being sold (or, in the event
of an underwritten offering, the managing underwriters) of the issuance by the
SEC of any stop order or other suspension of the effectiveness of the
Registration Statement at the earliest possible time and take all lawful action
to effect the withdrawal, recession or removal of such stop order or other
suspension;

            (g)   cooperate with the Holder to facilitate the timely preparation
and delivery of certificates for the Registrable Securities to be offered
pursuant to the Registration Statement and enable such certificates for the
Registrable Securities to be in such denominations or amounts, as the case may
be, as the Holder reasonably may request and registered in such names as the
Holder may request; and, within three Trading Days after a Registration
Statement which includes Registrable Securities is declared effective by the
SEC, deliver and cause legal counsel selected by the Company to deliver to the
transfer agent for the Registrable Securities (with copies to the Holder whose
Registrable Securities are included in such Registration Statement) an
appropriate instruction and, to the extent necessary, an opinion of such
counsel;

            (h)   take all such other lawful actions reasonably necessary to
expedite and facilitate the disposition by the Holder of their Registrable
Securities in accordance with the intended methods therefor provided in the
prospectus which are customary for issuers to perform under the circumstances;

<PAGE>

            (i)   in the event of an underwritten offering, promptly include or
incorporate in a Prospectus supplement or post-effective amendment to the
Registration Statement such information as the managers reasonably agree should
be included therein and to which the Company does not reasonably object and make
all required filings of such Prospectus supplement or post-effective amendment
as soon as practicable after it is notified of the matters to be included or
incorporated in such Prospectus supplement or post-effective amendment; and

            (j)   maintain a transfer agent and registrar for its Common Stock.

      Section 6. This Section not used.

      Section 7. Indemnification.

            (a)   The Company agrees to indemnify and hold harmless each Holder
and each person, if any, who controls such Holder within the meaning of the
Securities Act ("Distributing Holder") against any losses, claims, damages or
liabilities, joint or several (which shall, for all purposes of this Agreement,
include, but not be limited to, all reasonable costs of defense and
investigation and all reasonable attorneys' fees), to which the Distributing
Holder may become subject, under the Securities Act or otherwise, insofar as
such losses, claims, damages or liabilities (or actions in respect thereof)
arise out of or are based upon any untrue statement or alleged untrue statement
of any material fact contained in the Registration Statement, or any related
preliminary prospectus, final prospectus or amendment or supplement thereto, or
arise out of or are based upon the omission or alleged omission to state therein
a material fact required to be stated therein or necessary to make the
statements therein not misleading; provided, however, that the Company will not
be liable in any such case to the extent that any such loss, claim, damage or
liability arises out of or is based upon an untrue statement or alleged untrue
statement or omission or alleged omission made in the Registration Statement,
preliminary prospectus, final prospectus or amendment or supplement thereto in
reliance upon, and in conformity with, written information furnished to the
Company by the Distributing Holder, specifically for use in the preparation
thereof. This Section 7(a) shall not inure to the benefit of any Distributing
Holder with respect to any person asserting such loss, claim, damage or
liability who purchased the Registrable Securities which are the subject thereof
if the Distributing Holder failed to send or give (in violation of the
Securities Act or the rules and regulations promulgated thereunder) a copy of
the prospectus contained in such Registration Statement to such person at or
prior to the written confirmation to such person of the sale of such Registrable
Securities, where the Distributing Holder was obligated to do so under the
Securities Act or the rules and regulations promulgated thereunder. This
indemnity agreement will be in addition to any liability which the Company may
otherwise have.

            (b)   Each Distributing Holder agrees that it will indemnify and
hold harmless the Company, and each officer, director of the Company or person,
if any, who controls the Company within the meaning of the Securities Act,
against any losses, claims, damages or liabilities (which shall, for all
purposes of this Agreement, include, but not be limited to, all reasonable costs
of defense and investigation and all reasonable attorneys' fees) to which the
Company or any such officer, director or controlling person may become subject
under the Securities Act or otherwise, insofar as such losses, claims, damages
or liabilities (or actions in respect thereof) arise out of or are based upon

<PAGE>

any untrue statement or alleged untrue statement of any material fact contained
in the Registration Statement, or any related preliminary prospectus, final
prospectus or amendment or supplement thereto, or arise out of or are based upon
the omission or the alleged omission to state therein a material fact required
to be stated therein or necessary to make the statements therein not misleading,
but in each case only to the extent that such untrue statement or alleged untrue
statement or omission or alleged omission was made in the Registration
Statement, preliminary prospectus, final prospectus or amendment or supplement
thereto in reliance upon, and in conformity with, written information furnished
to the Company by such Distributing Holder, specifically for use in the
preparation thereof. This indemnity agreement will be in addition to any
liability which the Distributing Holder may otherwise have.

            (c)   Promptly after receipt by an indemnified party under this
Section 7 of notice of the commencement of any action, such indemnified party
will, if a claim in respect thereof is to be made against the indemnifying party
under this Section 7, notify the indemnifying party of the commencement thereof;
but the omission so to notify the indemnifying party will not relieve the
indemnifying party from any liability which it may have to any indemnified party
except to the extent of actual prejudice demonstrated by the indemnifying party.
In case any such action is brought against any indemnified party, and it
notifies the indemnifying party of the commencement thereof, the indemnifying
party will be entitled to participate in, and, to the extent that it may wish,
jointly with any other indemnifying party similarly notified, assume the defense
thereof, subject to the provisions herein stated and after notice from the
indemnifying party to such indemnified party of its election so to assume the
defense thereof, the indemnifying party will not be liable to such indemnified
party under this Section 7 for any legal or other expenses subsequently incurred
by such indemnified party in connection with the defense thereof other than
reasonable costs of investigation, unless the indemnifying party shall not
pursue the action to its final conclusion. The indemnified party shall have the
right to employ separate counsel in any such action and to participate in the
defense thereof, but the fees and expenses of such counsel shall not be at the
expense of the indemnifying party if the indemnifying party has assumed the
defense of the action with counsel reasonably satisfactory to the indemnified
party; provided that if the indemnified party is the Distributing Holder, the
fees and expenses of such counsel shall be at the expense of the indemnifying
party if (i) the employment of such counsel has been specifically authorized in
writing by the indemnifying party, or (ii) the named parties to any such action
(including any impleaded parties) include both the Distributing Holder and the
indemnifying party and the Distributing Holder shall have been advised by such
counsel that there may be one or more legal defenses available to the
indemnifying party different from or in conflict with any legal defenses which
may be available to the Distributing Holder (in which case the indemnifying
party shall not have the right to assume the defense of such action on behalf of
the Distributing Holder, it being understood, however, that the indemnifying
party shall, in connection with any one such action or separate but
substantially similar or related actions in the same jurisdiction arising out of
the same general allegations or circumstances, be liable only for the reasonable
fees and expenses of one separate firm of attorneys for the Distributing Holder,
which firm shall be designated in writing by the Distributing Holder). No
settlement of any action against an indemnified party shall be made without the
prior written consent of the indemnified party, which consent shall not be
unreasonably withheld.

<PAGE>

      Section 8. Contribution. In order to provide for just and equitable
contribution under the Securities Act in any case in which (i) the indemnified
party makes a claim for indemnification pursuant to Section 8 hereof but is
judicially determined (by the entry of a final judgment or decree by a court of
competent jurisdiction and the expiration of time to appeal or the denial of the
last right of appeal) that such indemnification may not be enforced in such case
notwithstanding the fact that the express provisions of Section 7 hereof provide
for indemnification in such case, or (ii) contribution under the Securities Act
may be required on the part of any indemnified party, then the Company and the
applicable Distributing Holder shall contribute to the aggregate losses, claims,
damages or liabilities to which they may be subject (which shall, for all
purposes of this Agreement, include, but not be limited to, all reasonable costs
of defense and investigation and all reasonable attorneys' fees), in either such
case (after contribution from others) on the basis of relative fault as well as
any other relevant equitable considerations. The relative fault shall be
determined by reference to, among other things, whether the untrue or alleged
untrue statement of a material fact or the omission or alleged omission to state
a material fact relates to information supplied by the Company on the one hand
or the applicable Distributing Holder on the other hand, and the parties'
relative intent, knowledge, access to information and opportunity to correct or
prevent such statement or omission. The Company and the Distributing Holder
agree that it would not be just and equitable if contribution pursuant to this
Section 8 were determined by pro rata allocation or by any other method of
allocation which does not take account of the equitable considerations referred
to in this Section 8. The amount paid or payable by an indemnified party as a
result of the losses, claims, damages or liabilities (or actions in respect
thereof) referred to above in this Section 8 shall be deemed to include any
legal or other expenses reasonably incurred by such indemnified party in
connection with investigating or defending any such action or claim. No person
guilty of fraudulent misrepresentation (within the meaning of Section 11(f) of
the Securities Act) shall be entitled to contribution from any person who was
not guilty of such fraudulent misrepresentation.

      Notwithstanding any other provision of this Section 8, in no event shall
any (i) Holder be required to undertake liability to any person under this
Section 8 for any amounts in excess of the dollar amount of the proceeds to be
received by such Holder from the sale of such Holder's Registrable Securities
(after deducting any fees, discounts and commissions applicable thereto)
pursuant to any Registration Statement under which such Registrable Securities
are to be registered under the Securities Act and (ii) underwriter be required
to undertake liability to any person hereunder for any amounts in excess of the
aggregate discount, commission or other compensation payable to such underwriter
with respect to the Registrable Securities underwritten by it and distributed
pursuant to the Registration Statement.

      Section 9. Notices. All notices, demands, requests, consents, approvals,
and other communications required or permitted hereunder shall be in writing
and, unless otherwise specified herein, shall be (i) personally served, (ii)
deposited in the mail, registered or certified, return receipt requested,
postage prepaid, (iii) delivered by reputable air courier service with charges
prepaid, or (iv) transmitted by hand delivery, telegram, or facsimile, addressed
as set forth below or to such other address as such party shall have specified
most recently by written notice. Any notice or other communication required or
permitted to be given hereunder shall be deemed effective (a) upon hand delivery
or delivery by facsimile, with accurate confirmation generated by the
transmitting facsimile machine, at the address or number designated below (if
delivered on a Trading Day during normal business hours where such notice is to
be received), or the first Trading Day following such delivery (if delivered
other than on a Trading Day during normal business hours where such notice is to
be received) or (b) on the second Trading Day following the date of mailing by
reputable courier service, fully prepaid, addressed to such address, or upon
actual receipt of such mailing, whichever shall first occur. The addresses for
such communications shall be:

<PAGE>

            If to the Company, at:

                     2727 W. Martin Luther King Blvd., Suite 850
                     Tampa, FL 33607

                     With copy to:

                     DARRIN M. OCASIO, ESQ.
                     SICHENZIA ROSS FRIEDMAN FERENCE LLP
                     1065 Avenue of the Americas, 21st flr.
                     New York, New York 10018
                     tel: 212-930-9700
                     fax:212-930-9725
                     dmocasio@srffllp.com

            If to the Purchaser, at:

                     Randall S. Goulding
                     The Nutmeg Group, L.L.C.
                     3366 Commercial
                     Northbrook IL 60062
                     tel: 847-291-7711
                     fax: 253-736-0134

      Either party hereto may from time to time change its address or facsimile
number for notices under this Section 9 by giving at least ten (10) days' prior
written notice of such changed address or facsimile number to the other party
hereto.

      Section 10. Assignment. This Agreement is binding upon and inures to the
benefit of the parties hereto and their respective heirs, successors and
permitted assigns. The rights granted the Holder under this Agreement may be
assigned to any purchaser of substantially all of the Registrable Securities (or
the rights thereto) from Holder, as otherwise permitted by the Subscription
Agreement. In the event of a transfer of the rights granted under this
Agreement, the Holder agrees that the Company may require that the transferee
comply with reasonable conditions as determined in the discretion of the
Company.

      Section 11. Additional Covenants of the Company. The Company agrees that
at such time as it meets all the requirements for the use of Securities Act
Registration Statement on Form S-3 it shall file all reports and information
required to be filed by it with the SEC in a timely manner and take all such
other action so as to maintain such eligibility for the use of such form.

<PAGE>

      Section 12. Counterparts/Facsimile. This Agreement may be executed in two
or more counterparts, each of which shall constitute an original, but all of
which, when together shall constitute but one and the same instrument, and shall
become effective when one or more counterparts have been signed by each party
hereto and delivered to the other party. In lieu of the original, a facsimile
transmission or copy of the original shall be as effective and enforceable as
the original.

      Section 13. Remedies. The remedies provided in this Agreement are
cumulative and not exclusive of any remedies provided by law. If any term,
provision, covenant or restriction of this Agreement is held by a court of
competent jurisdiction to be invalid, illegal, void or unenforceable, the
remainder of the terms, provisions, covenants and restrictions set forth herein
shall remain in full force and effect and shall in no way be affected, impaired
or invalidated, and the parties hereto shall use their best efforts to find and
employ an alternative means to achieve the same or substantially the same result
as that contemplated by such term, provision, covenant or restriction. It is
hereby stipulated and declared to be the intention of the parties that they
would have executed the remaining terms, provisions, covenants and restrictions
without including any of such that may be hereafter declared invalid, illegal,
void or unenforceable.

      Section 14. Conflicting Agreements. The Company shall not enter into any
agreement with respect to its securities that is inconsistent with the rights
granted to the holders of Registrable Securities in this Agreement or otherwise
prevents the Company from complying with all of its obligations hereunder.

      Section 15. Headings. The headings in this Agreement are for reference
purposes only and shall not affect in any way the meaning or interpretation of
this Agreement.

      Section 16. Governing Law, Arbitration. This Agreement shall be governed
by and construed in accordance with the laws of the State of Illinois applicable
to contracts made in Illinois by persons domiciled in Chicago and without regard
to its principles of conflicts of laws. Any dispute under this Agreement shall
be submitted to arbitration under the matters at issue selected by the parties
in accordance with the commercial arbitration rules of the Better Business
Bureau (the "BBB") or the American Arbitration Association (the "AAA") in
Chicago, Illinois, and shall be finally and conclusively determined by the
decision of a board of arbitration consisting of three (3) members (hereinafter
referred to as the "Board of Arbitration") selected as according to the rules
governing the BBB or the AAA. The Board of Arbitration shall meet on consecutive
Trading Days in Chicago, Illinois, and shall reach and render a decision in
writing (concurred in by a majority of the members of the Board of Arbitration)
with respect to the amount, if any, which the losing party is required to pay to
the other party in respect of a claim filed. In connection with rendering its
decisions, the Board of Arbitration shall adopt and follow the laws of the State
of Illinois. To the extent practical, decisions of the Board of Arbitration
shall be rendered no more than thirty (30) calendar days following commencement
of proceedings with respect thereto. The Board of Arbitration shall cause its
written decision to be delivered to all parties involved in the dispute. Any
decision made by the Board of Arbitration (either prior to or after the
expiration of such thirty (30) calendar day period) shall be final, binding and
conclusive on the parties to the dispute, and entitled to be enforced to the
fullest extent permitted by law and entered in any court of competent
jurisdiction. The non-prevailing party to any arbitration (as determined by the
Board of Arbitration) shall pay the expenses of the prevailing party, including
reasonable attorneys' fees, in connection with such arbitration.

<PAGE>

      Section 17. Severability. If any provision of this Agreement shall for any
reason be held invalid or unenforceable, such invalidity or unenforceablity
shall not affect any other provision hereof and this Agreement shall be
construed as if such invalid or unenforceable provision had never been contained
herein.

      Section 18. Capitalized Terms. All capitalized terms not otherwise defined
herein shall have the meaning assigned to them in the Subscription Agreement.

      IN WITNESS WHEREOF, the parties hereto have caused this Registration
Rights Agreement to be duly executed, on the day and year first above written.

                                          NANOBAC PHARMACEUTICALS, INCORPORATED

                                          By: /s/Alexander Edwards III
                                             -----------------------------------
                                          Its: Director
                                              ----------------------------------

                                          THE NUTMEG GROUP, L.L.C.

                                          By:  /s/ Randall S. Goulding
                                             -----------------------------------
                                          Its: Managing Director
                                              ----------------------------------

<PAGE>

                                 FORM OF WARRANT

THE WARRANT REPRESENTED BY THIS CERTIFICATE AND THE SECURITIES TO BE ISSUED UPON
ITS EXERCISE HAVE NOT BEEN REGISTERED UNDER THE UNITED STATES SECURITIES ACT OF
1933 (THE "SECURITIES ACT") OR APPLICABLE STATE SECURITIES LAWS (THE "STATE
ACTS") AND SHALL NOT BE SOLD OR TRANSFERRED UNLESS SUCH SALE OR TRANSFER HAS
BEEN REGISTERED UNDER THE SECURITIES ACT AND STATE ACTS, OR AN EXEMPTION FROM
THE REGISTRATION REQUIREMENTS IS AVAILABLE, THE AVAILABILITY OF WHICH MUST BE
ESTABLISHED TO THE SATISFACTION OF THE COMPANY.

                         CLASS A STOCK PURCHASE WARRANT
1.

2.    Warrant No.                                              Number of Shares:

                      NANOBAC PHARMACEUTICALS, INCORPORATED
                      COMMON STOCK, NO PAR VALUE PER SHARE
                        VOID AFTER 5:00 P.M. EASTERN TIME
                              ON ____________, 2008

      This Warrant is issued to ___________________________________________
("Holder") by Nanobac Pharmaceuticals, Incorporated, a Delaware corporation
(hereinafter with its successors called the "Company").

For value received and subject to the terms and conditions hereinafter set out,
Holder is entitled to purchase from the Company at an initial purchase price of
$___per share, _______________________________fully paid and nonassessable
shares of common stock, no par value per share ("Common Shares") of the Company.
Such purchase price per Common Share, adjusted from time to time as provided
herein, is referred to as the "Purchase Price."

1.             1.The Holder may exercise this Warrant, in whole or in part, upon
surrender of this Warrant, with the exercise form annexed hereto duly executed,
at the office of the Company, _____________, or such other office as the Company
shall notify the Holder in writing, together with a certified or bank cashier's
check payable to the order of the Company in the amount of the Purchase Price
times the number of Common Shares being purchased.

<PAGE>

      2.    The person or persons in whose name or names any certificate
representing Common Shares is issued hereunder shall be deemed to have become
the holder of record of the Common Shares represented thereby as of the close of
business on the date on which this Warrant is exercised with respect to such
shares, whether or not the transfer books of the Company shall be closed. Until
such time as this Warrant is exercised or terminates, the Purchase Price payable
and the number and character of securities issuable upon exercise of this
Warrant are subject to adjustment as hereinafter provided.

      3.    Unless previously exercised, this Warrant shall expire at 5:00 p.m.
Eastern Time, On December 31, 2008 and shall be void thereafter or can be
extended at the Company's discretion ("Expiration Date").

      4.    The Company covenants that it will at all times reserve and keep
available a number of its authorized Common Shares, free from all preemptive
rights, which will be sufficient to permit the exercise of this Warrant. The
Company further covenants that such shares as may be issued pursuant to the
exercise of this Warrant will, upon issuance, be duly and validly issued, fully
paid and nonassessable and free from all taxes, liens, and charges.

      5.    If the Company subdivides its outstanding Common Shares, by split-up
or otherwise, or combines its outstanding Common Shares, the Purchase Price then
applicable to shares covered by this Warrant shall forthwith be proportionately
decreased in the case of a subdivision, or proportionately increased in the case
of a combination.

      6.    If (a) the Company reorganizes its capital, reclassifies its capital
stock, consolidates or merges with or into another corporation (but only if the
Company is not the surviving corporation and no longer has more than a single
shareholder) or sells, transfers or otherwise disposes of all or substantially
all its property, assets, or business to another corporation, and (b) pursuant
to the terms of such reorganization, reclassification, merger, consolidation, or
disposition of assets, shares of common stock of the successor or acquiring
corporation, or any cash, shares of stock, or other securities or property of
any nature whatsoever (including warrants or other subscription or purchase
rights) in addition to or in lieu of common stock of the successor or acquiring
corporation ("Other Property"), are to be received by or distributed to the
holders of Common Shares, then (c) Holder shall have the right thereafter to
receive, upon exercise of this Warrant, the same number of shares of common
stock of the successor or acquiring corporation and Other Property receivable
upon such reorganization, reclassification, merger, consolidation, or
disposition of assets as a holder of the number of Common Shares for which this
Warrant is exercisable immediately prior to such event. At the time of such
reorganization, reclassification, merger, consolidation or disposition of
assets, the successor or acquiring corporation shall expressly assume the due
and punctual observance and performance of each and every covenant and condition

<PAGE>

of this Warrant to be performed and observed by the Company and all the
obligations and liabilities hereunder, subject to such modifications as may be
deemed appropriate (as determined by resolution of the Board of Directors of the
Company) in order to adjust the number of shares of the common stock of the
successor or acquiring corporation for which this Warrant is exercisable. For
purposes of this section, "common stock of the successor or acquiring
corporation" shall include stock of such corporation of any class which is not
preferred as to dividends or assets over any other class of stock of such
corporation and which is not subject to redemption and shall also include any
evidences of indebtedness, shares of stock, or other securities which are
convertible into or exchangeable for any such stock, either immediately or upon
the arrival of a specified date or the happening of a specified event and any
warrants or other rights to subscribe for or purchase any such stock. The
foregoing provisions of this section shall similarly apply to successive
reorganizations, reclassifications, mergers, consolidations, or disposition of
assets.

      7.    If a voluntary or involuntary dissolution, liquidation or winding up
of the Company (other than in connection with a merger or consolidation of the
Company) is at any time proposed during the term of this Warrant, the Company
shall give written notice to the Holder at least thirty days prior to the record
date of the proposed transaction. The notice shall contain: (1) the date on
which the transaction is to take place; (2) the record date (which must be at
least thirty days after the giving of the notice) as of which holders of the
Common Shares entitled to receive distributions as a result of the transaction
shall be determined; (3) a brief description of the transaction; (4) a brief
description of the distributions, if any, to be made to holders of the Common
Shares as a result of the transaction; and (5) an estimate of the fair market
value of the distributions. On the date of the transaction, if it actually
occurs, this Warrant and all rights existing under this Warrant shall terminate.

      8.    In no event shall any fractional Common Share of the Company be
issued upon any exercise of this Warrant. If, upon exercise of this Warrant as
an entirety, the Holder would, except as provided in this Section 8, be entitled
to receive a fractional Common Share, then the Company shall issue the next
higher number of full Common Shares, issuing a full share with respect to such
fractional share. If this Warrant is exercised at one time for less than the
maximum number of Common Shares purchasable upon the exercise hereof, the
Company shall issue to the Holder a new warrant of like tenor and date
representing the number of Common Shares equal to the difference between the
number of shares purchasable upon full exercise of this Warrant and the number
of shares that were purchased upon the exercise of this Warrant.

      9.    No adjustments in the Purchase Price shall be required unless such
adjustment would require an increase or decrease of at least five cents in such
price, provided however, that any adjustments which by reason of this Section 9
are not required to be made shall be carried forward and taken into account in
any subsequent adjustment.

      10.   Whenever the Purchase Price is adjusted, as herein provided, the
Company shall promptly deliver to the Holder a certificate setting forth the
Purchase Price after such adjustment and setting forth a brief statement of the
facts requiring such adjustment.

      11.   If at any time prior to the expiration or exercise of this Warrant,
the Company shall pay any dividend or make any distribution upon its Common
Shares or shall make any subdivision or combination of, or other change in its
Common Shares, the Company shall cause notice thereof to be mailed, first class,
postage prepaid, to Holder at least thirty full business days prior to the
record date set for determining the holders of Common Shares who shall
participate in such dividend, distribution, subdivision, combination or other
change. Such notice shall also specify the record date as of which holders of
Common Shares who shall participate in such dividend or distribution are to be
determined. Failure to give such notice, or any defect therein, shall not affect
the legality or validity of any dividend or distribution.

<PAGE>

      12.   The Company will maintain a register containing the names and
addresses of the Holder and any assignees of this Warrant. Holder may change its
address as shown on the warrant register by written notice to the Company
requesting such change. Any notice or written communication required or
permitted to be given to the Holder may be delivered by confirmed facsimile or
telecopy or by a recognized overnight courier, addressed to Holder at the
address shown on the warrant register.

      13.   This Warrant has not been registered under the Securities Act of
1933, as amended (the "Securities Act"), or any state securities laws ("State
Acts") or regulations in reliance upon exemptions under the Securities Act, and
exemptions under the State Acts. Subject to compliance with the Securities Act
and State Acts, this Warrant and all rights hereunder are transferable in whole
or in part, at the office of the Company at which this Warrant is exercisable,
upon surrender of this Warrant together with the assignment hereof properly
endorsed.

      14.   In case this Warrant shall be mutilated, lost, stolen, or destroyed,
the Company may issue a new warrant of like tenor and denomination and deliver
the same (a) in exchange and substitution for and upon surrender and
cancellation of any mutilated Warrant, or (b) in lieu of any Warrant lost,
stolen, or destroyed, upon receipt of evidence satisfactory to the Company of
the loss, theft or destruction of such Warrant (including a reasonably detailed
affidavit with respect to the circumstances of any loss, theft, or destruction)
and of indemnity with sufficient surety satisfactory to the Company.

      15.   Unless a current registration statement under the Securities Act,
shall be in effect with respect to the securities to be issued upon exercise of
this Warrant, the Holder, by accepting this Warrant, covenants and agrees that,
at the time of exercise hereof, and at the time of any proposed transfer of
securities acquired upon exercise hereof, the Company may require Holder to make
such representations, and may place such legends on certificates representing
the Common Shares issuable upon exercise of this Warrant, as may be reasonably
required in the opinion of counsel to the Company to permit such Common Shares
to be issued without such registration.

      16.   The Company has granted the Holder piggy back registration rights,
for the Common Stock underlying the Warrant.

      17.   For so long as a registration statement covering the shares
underlying this Warrant is effective, the closing bid price for the Company's
Common Stock exceeds 50% of the exercise price of this Warrant for 30 days and
the average daily trading volume for such 30 days exceeds the number of
Warrants, then the Company shall have the right to compel the Holder to exercise
the Warrants, upon written notice. In the event the Holder does not exercise
such Warrants upon notice then the Warrant shall expire on the 30th trading day
after such notice is given.

<PAGE>

      18.   This Warrant does not entitle Holder to any of the rights of a
stockholder of the Company.

      19.   Nothing expressed in this Agreement and nothing that may be implied
from any of the provisions hereof is intended, or shall be construed, to confer
upon, or give to, any person or corporation other than the parties to this
Agreement any covenant, condition, stipulation, promise, or agreement contained
herein, and all covenants, conditions, stipulations, promises and agreements
contained herein shall be for the sole and exclusive benefit of the parties
hereto and their respective successors and assigns.

      20.   The provisions and terms of this Warrant shall be construed in
accordance with the laws of the State of Florida.

      IN WITNESS WHEREOF, this Warrant has been duly executed by the Company as
of the ___ day of ___________, 2004.

                                NANOBAC PHARMACEUTICALS, INCORPORATED

                                By:_______________________________

<PAGE>

                                FORM OF EXERCISE

                                                      Date: ____________________

To:   Nanobac Pharmaceuticals, Incorporated

      The undersigned hereby subscribes for _______ shares of common stock of
Nanobac Pharmaceuticals, Incorporated covered by this Warrant and hereby
delivers $___________ in full payment of the purchase price thereof. The
certificate(s) for such shares should be issued in the name of the undersigned
or as otherwise indicated below:

                                            ----------------------------
                                            Signature:

                                            ----------------------------
                                            Printed Name

                                            ----------------------------
                                            Name for Registration, if different

                                            ----------------------------
                                            Street Address

                                            ----------------------------
                                            City, State and Zip Code

                                            ----------------------------
                                            Social Security Number

<PAGE>

                                   ASSIGNMENT

      For Value Received, the undersigned hereby sells, assigns and transfers
unto the assignee(s) set forth below the within Warrant certificate, together
with all right, title and interest therein, and hereby irrevocably constitutes
and appoints ___________________________________ attorney, to transfer the said
Warrant on the books of the within-named Company with respect to the number of
Common Shares set forth below, with full power of substitution in the premises.

               Social Security or
               other Identifying
Name(s) of     Number(s) of No. of
Assignee(s)    Assignee(s)                Address      Shares
----------     -------------------        -------      -------

Dated: ______________________________

                                    ------------------------------------
                                    Signature

                                    NOTICE: THE SIGNATURE TO THIS ASSIGNMENT
                                    MUST CORRESPOND WITH THE NAME AS WRITTEN
                                    UPON THE FACE OF THE WARRANT IN EVERY
                                    PARTICULAR, WITHOUT ALTERATION OR
                                    ENLARGEMENT, OR ANY CHANGE WHATSOEVER.

                                    ------------------------------------
                                    Print Name and Title

<PAGE>

                                 FORM OF WARRANT

THE WARRANT REPRESENTED BY THIS CERTIFICATE AND THE SECURITIES TO BE ISSUED UPON
ITS EXERCISE HAVE NOT BEEN REGISTERED UNDER THE UNITED STATES SECURITIES ACT OF
1933 (THE "SECURITIES ACT") OR APPLICABLE STATE SECURITIES LAWS (THE "STATE
ACTS") AND SHALL NOT BE SOLD OR TRANSFERRED UNLESS SUCH SALE OR TRANSFER HAS
BEEN REGISTERED UNDER THE SECURITIES ACT AND STATE ACTS, OR AN EXEMPTION FROM
THE REGISTRATION REQUIREMENTS IS AVAILABLE, THE AVAILABILITY OF WHICH MUST BE
ESTABLISHED TO THE SATISFACTION OF THE COMPANY.

                         CLASS B STOCK PURCHASE WARRANT
3.

4.    Warrant No.                                              Number of Shares:

                      NANOBAC PHARMACEUTICALS, INCORPORATED
                      COMMON STOCK, NO PAR VALUE PER SHARE
                        VOID AFTER 5:00 P.M. EASTERN TIME
                              ON ____________, 2008

      This Warrant is issued to ___________________________________________
("Holder") by Nanobac Pharmaceuticals, Incorporated, a Delaware corporation
(hereinafter with its successors called the "Company").

For value received and subject to the terms and conditions hereinafter set out,
Holder is entitled to purchase from the Company at an initial purchase price of
$___per share, _______________________________fully paid and nonassessable
shares of common stock, no par value per share ("Common Shares") of the Company.
Such purchase price per Common Share, adjusted from time to time as provided
herein, is referred to as the "Purchase Price."

1.              1.The Holder may exercise this Warrant, in whole or in part,
upon surrender of this Warrant, with the exercise form annexed hereto duly
executed, at the office of the Company, _____________, or such other office as
the Company shall notify the Holder in writing, together with a certified or
bank cashier's check payable to the order of the Company in the amount of the
Purchase Price times the number of Common Shares being purchased.

      4.    The person or persons in whose name or names any certificate
representing Common Shares is issued hereunder shall be deemed to have become
the holder of record of the Common Shares represented thereby as of the close of
business on the date on which this Warrant is exercised with respect to such
shares, whether or not the transfer books of the Company shall be closed. Until
such time as this Warrant is exercised or terminates, the Purchase Price payable
and the number and character of securities issuable upon exercise of this
Warrant are subject to adjustment as hereinafter provided.

<PAGE>

      5.    Unless previously exercised, this Warrant shall expire at 5:00 p.m.
Eastern Time, On December 31, 2008 and shall be void thereafter or can be
extended at the Company's discretion ("Expiration Date").

      4.    The Company covenants that it will at all times reserve and keep
available a number of its authorized Common Shares, free from all preemptive
rights, which will be sufficient to permit the exercise of this Warrant. The
Company further covenants that such shares as may be issued pursuant to the
exercise of this Warrant will, upon issuance, be duly and validly issued, fully
paid and nonassessable and free from all taxes, liens, and charges.

      5.    If the Company subdivides its outstanding Common Shares, by split-up
or otherwise, or combines its outstanding Common Shares, the Purchase Price then
applicable to shares covered by this Warrant shall forthwith be proportionately
decreased in the case of a subdivision, or proportionately increased in the case
of a combination.

      6.    If (a) the Company reorganizes its capital, reclassifies its capital
stock, consolidates or merges with or into another corporation (but only if the
Company is not the surviving corporation and no longer has more than a single
shareholder) or sells, transfers or otherwise disposes of all or substantially
all its property, assets, or business to another corporation, and (b) pursuant
to the terms of such reorganization, reclassification, merger, consolidation, or
disposition of assets, shares of common stock of the successor or acquiring
corporation, or any cash, shares of stock, or other securities or property of
any nature whatsoever (including warrants or other subscription or purchase
rights) in addition to or in lieu of common stock of the successor or acquiring
corporation ("Other Property"), are to be received by or distributed to the
holders of Common Shares, then (c) Holder shall have the right thereafter to
receive, upon exercise of this Warrant, the same number of shares of common
stock of the successor or acquiring corporation and Other Property receivable
upon such reorganization, reclassification, merger, consolidation, or
disposition of assets as a holder of the number of Common Shares for which this
Warrant is exercisable immediately prior to such event. At the time of such
reorganization, reclassification, merger, consolidation or disposition of
assets, the successor or acquiring corporation shall expressly assume the due
and punctual observance and performance of each and every covenant and condition
of this Warrant to be performed and observed by the Company and all the
obligations and liabilities hereunder, subject to such modifications as may be
deemed appropriate (as determined by resolution of the Board of Directors of the
Company) in order to adjust the number of shares of the common stock of the
successor or acquiring corporation for which this Warrant is exercisable. For
purposes of this section, "common stock of the successor or acquiring

<PAGE>

corporation" shall include stock of such corporation of any class which is not
preferred as to dividends or assets over any other class of stock of such
corporation and which is not subject to redemption and shall also include any
evidences of indebtedness, shares of stock, or other securities which are
convertible into or exchangeable for any such stock, either immediately or upon
the arrival of a specified date or the happening of a specified event and any
warrants or other rights to subscribe for or purchase any such stock. The
foregoing provisions of this section shall similarly apply to successive
reorganizations, reclassifications, mergers, consolidations, or disposition of
assets.

      7.    If a voluntary or involuntary dissolution, liquidation or winding up
of the Company (other than in connection with a merger or consolidation of the
Company) is at any time proposed during the term of this Warrant, the Company
shall give written notice to the Holder at least thirty days prior to the record
date of the proposed transaction. The notice shall contain: (1) the date on
which the transaction is to take place; (2) the record date (which must be at
least thirty days after the giving of the notice) as of which holders of the
Common Shares entitled to receive distributions as a result of the transaction
shall be determined; (3) a brief description of the transaction; (4) a brief
description of the distributions, if any, to be made to holders of the Common
Shares as a result of the transaction; and (5) an estimate of the fair market
value of the distributions. On the date of the transaction, if it actually
occurs, this Warrant and all rights existing under this Warrant shall terminate.

      8.    In no event shall any fractional Common Share of the Company be
issued upon any exercise of this Warrant. If, upon exercise of this Warrant as
an entirety, the Holder would, except as provided in this Section 8, be entitled
to receive a fractional Common Share, then the Company shall issue the next
higher number of full Common Shares, issuing a full share with respect to such
fractional share. If this Warrant is exercised at one time for less than the
maximum number of Common Shares purchasable upon the exercise hereof, the
Company shall issue to the Holder a new warrant of like tenor and date
representing the number of Common Shares equal to the difference between the
number of shares purchasable upon full exercise of this Warrant and the number
of shares that were purchased upon the exercise of this Warrant.

      9.    No adjustments in the Purchase Price shall be required unless such
adjustment would require an increase or decrease of at least five cents in such
price, provided however, that any adjustments which by reason of this Section 9
are not required to be made shall be carried forward and taken into account in
any subsequent adjustment.

      10.   Whenever the Purchase Price is adjusted, as herein provided, the
Company shall promptly deliver to the Holder a certificate setting forth the
Purchase Price after such adjustment and setting forth a brief statement of the
facts requiring such adjustment.

      11.   If at any time prior to the expiration or exercise of this Warrant,
the Company shall pay any dividend or make any distribution upon its Common
Shares or shall make any subdivision or combination of, or other change in its
Common Shares, the Company shall cause notice thereof to be mailed, first class,
postage prepaid, to Holder at least thirty full business days prior to the
record date set for determining the holders of Common Shares who shall
participate in such dividend, distribution, subdivision, combination or other
change. Such notice shall also specify the record date as of which holders of
Common Shares who shall participate in such dividend or distribution are to be
determined. Failure to give such notice, or any defect therein, shall not affect
the legality or validity of any dividend or distribution.

<PAGE>

      12.   The Company will maintain a register containing the names and
addresses of the Holder and any assignees of this Warrant. Holder may change its
address as shown on the warrant register by written notice to the Company
requesting such change. Any notice or written communication required or
permitted to be given to the Holder may be delivered by confirmed facsimile or
telecopy or by a recognized overnight courier, addressed to Holder at the
address shown on the warrant register.

      13.   This Warrant has not been registered under the Securities Act of
1933, as amended (the "Securities Act"), or any state securities laws ("State
Acts") or regulations in reliance upon exemptions under the Securities Act, and
exemptions under the State Acts. Subject to compliance with the Securities Act
and State Acts, this Warrant and all rights hereunder are transferable in whole
or in part, at the office of the Company at which this Warrant is exercisable,
upon surrender of this Warrant together with the assignment hereof properly
endorsed.

      14.   In case this Warrant shall be mutilated, lost, stolen, or destroyed,
the Company may issue a new warrant of like tenor and denomination and deliver
the same (a) in exchange and substitution for and upon surrender and
cancellation of any mutilated Warrant, or (b) in lieu of any Warrant lost,
stolen, or destroyed, upon receipt of evidence satisfactory to the Company of
the loss, theft or destruction of such Warrant (including a reasonably detailed
affidavit with respect to the circumstances of any loss, theft, or destruction)
and of indemnity with sufficient surety satisfactory to the Company.

      15.   Unless a current registration statement under the Securities Act,
shall be in effect with respect to the securities to be issued upon exercise of
this Warrant, the Holder, by accepting this Warrant, covenants and agrees that,
at the time of exercise hereof, and at the time of any proposed transfer of
securities acquired upon exercise hereof, the Company may require Holder to make
such representations, and may place such legends on certificates representing
the Common Shares issuable upon exercise of this Warrant, as may be reasonably
required in the opinion of counsel to the Company to permit such Common Shares
to be issued without such registration.

      16.   The Company has granted the Holder piggy back registration rights,
for the Common Stock underlying the Warrant.

      17.   This Warrant does not entitle Holder to any of the rights of a
stockholder of the Company.

      18.   Nothing expressed in this Agreement and nothing that may be implied
from any of the provisions hereof is intended, or shall be construed, to confer
upon, or give to, any person or corporation other than the parties to this
Agreement any covenant, condition, stipulation, promise, or agreement contained
herein, and all covenants, conditions, stipulations, promises and agreements
contained herein shall be for the sole and exclusive benefit of the parties
hereto and their respective successors and assigns.

<PAGE>

      19.   The provisions and terms of this Warrant shall be construed in
accordance with the laws of the State of Florida.

      IN WITNESS WHEREOF, this Warrant has been duly executed by the Company as
of the ___ day of ___________, 2004.

                                    NANOBAC PHARMACEUTICALS, INCORPORATED

                                    By:_______________________________

<PAGE>

                                FORM OF EXERCISE

                                                      Date: ____________________

To:   Nanobac Pharmaceuticals, Incorporated

      The undersigned hereby subscribes for _______ shares of common stock of
Nanobac Pharmaceuticals, Incorporated covered by this Warrant and hereby
delivers $___________ in full payment of the purchase price thereof. The
certificate(s) for such shares should be issued in the name of the undersigned
or as otherwise indicated below:

                                           ----------------------------
                                           Signature:

                                           ----------------------------
                                           Printed Name

                                           ----------------------------
                                           Name for Registration, if different

                                           ----------------------------
                                           Street Address

                                           ----------------------------
                                           City, State and Zip Code

                                           ----------------------------
                                           Social Security Number

<PAGE>

                                   ASSIGNMENT

      For Value Received, the undersigned hereby sells, assigns and transfers
unto the assignee(s) set forth below the within Warrant certificate, together
with all right, title and interest therein, and hereby irrevocably constitutes
and appoints ___________________________________ attorney, to transfer the said
Warrant on the books of the within-named Company with respect to the number of
Common Shares set forth below, with full power of substitution in the premises.

               Social Security or
               other Identifying
Name(s) of     Number(s) of No. of
Assignee(s)    Assignee(s)                Address      Shares
-----------    --------------------       -------      ------

Dated: ______________________________

                                    ------------------------------------
                                    Signature

                                    NOTICE: THE SIGNATURE TO THIS ASSIGNMENT
                                    MUST CORRESPOND WITH THE NAME AS WRITTEN
                                    UPON THE FACE OF THE WARRANT IN EVERY
                                    PARTICULAR, WITHOUT ALTERATION OR
                                    ENLARGEMENT, OR ANY CHANGE WHATSOEVER.

                                    ------------------------------------
                                    Print Name and Title

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