Document:

Indenture, Dated as of August 14, 2012

 Exhibit 4.1 
 EXELIXIS, INC., 
 as Issuer 

AND 

WELLS FARGO BANK, NATIONAL ASSOCIATION, 
 as Trustee 
  

 
 INDENTURE

 Dated as of August 14, 2012 

 
  

Debt Securities 

									
	ARTICLE 1     DEFINITIONS	  	 	1	  
				
		 	Section 1.01	 	 Definitions of Terms
	  	 	1	  
		
	 ARTICLE 2     ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF
SECURITIES
	  	 	6	  
				
		 	Section 2.01	 	 Designation and Terms of Securities
	  	 	6	  
				
		 	Section 2.02	 	 Form of Securities and Trustee’s Certificate
	  	 	9	  
				
		 	Section 2.03	 	 Denominations: Provisions for Payment
	  	 	9	  
				
		 	Section 2.04	 	 Execution and Authentications
	  	 	11	  
				
		 	Section 2.05	 	 Registration of Transfer and Exchange
	  	 	11	  
				
		 	Section 2.06	 	 Temporary Securities
	  	 	13	  
				
		 	Section 2.07	 	 Mutilated, Destroyed, Lost or Stolen Securities
	  	 	13	  
				
		 	Section 2.08	 	 Cancellation
	  	 	14	  
				
		 	Section 2.09	 	 Benefits of Indenture
	  	 	14	  
				
		 	Section 2.10	 	 Authenticating Agent
	  	 	15	  
				
		 	Section 2.11	 	 Global Securities
	  	 	15	  
		
	 ARTICLE 3     REDEMPTION OF SECURITIES AND SINKING FUND PROVISIONS
	  	 	17	  
				
		 	Section 3.01	 	 Redemption
	  	 	17	  
				
		 	Section 3.02	 	 Notice of Redemption
	  	 	17	  
				
		 	Section 3.03	 	 Payment Upon Redemption
	  	 	18	  
				
		 	Section 3.04	 	 Sinking Fund
	  	 	19	  
				
		 	Section 3.05	 	 Satisfaction of Sinking Fund Payments with Securities
	  	 	19	  
				
		 	Section 3.06	 	 Redemption of Securities for Sinking Fund
	  	 	19	  
		
	ARTICLE 4     COVENANTS	  	 	20	  
				
		 	Section 4.01	 	 Payment of Principal, Premium and Interest
	  	 	20	  
				
		 	Section 4.02	 	 Maintenance of Office or Agency
	  	 	20	  
				
		 	Section 4.03	 	 Paying Agents
	  	 	20	  
				
		 	Section 4.04	 	 Appointment to Fill Vacancy in Office of Trustee
	  	 	21	  
				
		 	Section 4.05	 	 Compliance with Consolidation Provisions
	  	 	22	  
		
	 ARTICLE 5     SECURITYHOLDERS’ LISTS AND REPORTS BY THE COMPANY AND
THE TRUSTEE
	  	 	22	  
				
		 	Section 5.01	 	 Company to Furnish Trustee Names and Addresses of Securityholders
	  	 	22	  

  
 i. 

									
				
		 	Section 5.02	 	 Preservation Of Information; Communications With Securityholders
	  	 	22	  
				
		 	Section 5.03	 	 Reports by the Company
	  	 	23	  
				
		 	Section 5.04	 	 Reports by the Trustee
	  	 	23	  
		
	 ARTICLE 6     REMEDIES OF THE TRUSTEE AND SECURITYHOLDERS ON EVENT OF DEFAULT
	  	 	23	  
				
		 	Section 6.01	 	 Events of Default
	  	 	24	  
				
		 	Section 6.02	 	 Collection of Indebtedness and Suits for Enforcement by Trustee
	  	 	25	  
				
		 	Section 6.03	 	 Application of Moneys Collected
	  	 	27	  
				
		 	Section 6.04	 	 Limitation on Suits
	  	 	27	  
				
		 	Section 6.05	 	 Rights and Remedies Cumulative; Delay or Omission Not Waiver
	  	 	28	  
				
		 	Section 6.06	 	 Control by Securityholders
	  	 	29	  
				
		 	Section 6.07	 	 Undertaking to Pay Costs
	  	 	29	  
		
	ARTICLE 7     CONCERNING THE TRUSTEE	  	 	30	  
				
		 	Section 7.01	 	 Certain Duties and Responsibilities of Trustee
	  	 	30	  
				
		 	Section 7.02	 	 Certain Rights of Trustee
	  	 	31	  
				
		 	Section 7.03	 	 Trustee Not Responsible for Recitals or Issuance or Securities
	  	 	33	  
				
		 	Section 7.04	 	 May Hold Securities
	  	 	33	  
				
		 	Section 7.05	 	 Moneys Held in Trust
	  	 	34	  
				
		 	Section 7.06	 	 Compensation and Reimbursement
	  	 	34	  
				
		 	Section 7.07	 	 Reliance on Officer’s Certificate
	  	 	35	  
				
		 	Section 7.08	 	 Disqualification; Conflicting Interests
	  	 	35	  
				
		 	Section 7.09	 	 Corporate Trustee Required; Eligibility
	  	 	35	  
				
		 	Section 7.10	 	 Resignation and Removal; Appointment of Successor
	  	 	35	  
				
		 	Section 7.11	 	 Acceptance of Appointment By Successor
	  	 	37	  
				
		 	Section 7.12	 	 Merger, Conversion, Consolidation or Succession to Business
	  	 	38	  
				
		 	Section 7.13	 	 Preferential Collection of Claims Against the Company
	  	 	38	  
				
		 	Section 7.14	 	 Notice of Default
	  	 	38	  
		
	ARTICLE 8     CONCERNING THE SECURITYHOLDERS	  	 	39	  
				
		 	Section 8.01	 	 Evidence of Action by Securityholders
	  	 	39	  
				
		 	Section 8.02	 	 Proof of Execution by Securityholders
	  	 	39	  

  
 ii.

									
				
		 	Section 8.03	 	 Who May be Deemed Owners
	  	 	40	  
				
		 	Section 8.04	 	 Certain Securities Owned by Company Disregarded
	  	 	40	  
				
		 	Section 8.05	 	 Actions Binding on Future Securityholders
	  	 	41	  
		
	ARTICLE 9     SUPPLEMENTAL INDENTURES	  	 	41	  
				
		 	Section 9.01	 	 Supplemental Indentures Without the Consent of Securityholders
	  	 	41	  
				
		 	Section 9.02	 	 Supplemental Indentures With Consent of Securityholders
	  	 	42	  
				
		 	Section 9.03	 	 Effect of Supplemental Indentures
	  	 	43	  
				
		 	Section 9.04	 	 Securities Affected by Supplemental Indentures
	  	 	43	  
				
		 	Section 9.05	 	 Execution of Supplemental Indentures
	  	 	43	  
		
	ARTICLE 10     SUCCESSOR ENTITY	  	 	44	  
				
		 	Section 10.01	 	 Company May Consolidate, Etc.
	  	 	44	  
				
		 	Section 10.02	 	 Successor Entity Substituted
	  	 	44	  
		
	ARTICLE 11     SATISFACTION AND DISCHARGE	  	 	45	  
				
		 	Section 11.01	 	 Satisfaction and Discharge of Indenture
	  	 	45	  
				
		 	Section 11.02	 	 Discharge of Obligations
	  	 	46	  
				
		 	Section 11.03	 	 Deposited Moneys to be Held in Trust
	  	 	46	  
				
		 	Section 11.04	 	 Payment of Moneys Held by Paying Agents
	  	 	46	  
				
		 	Section 11.05	 	 Repayment to Company
	  	 	46	  
		
	 ARTICLE 12     IMMUNITY OF INCORPORATORS, STOCKHOLDERS, OFFICERS AND DIRECTORS
	  	 	47	  
				
		 	Section 12.01	 	No Recourse	  	 	47	  
		
	 ARTICLE 13     MISCELLANEOUS PROVISIONS
	  	 	47	  
				
		 	Section 13.01	 	Effect on Successors and Assigns	  	 	47	  
				
		 	Section 13.02	 	Actions by Successor	  	 	47	  
				
		 	Section 13.03	 	Surrender of Company Powers	  	 	48	  
				
		 	Section 13.04	 	Notices	  	 	48	  
				
		 	Section 13.05	 	Governing Law	  	 	48	  
				
		 	Section 13.06	 	Treatment of Securities as Debt	  	 	48	  
				
		 	Section 13.07	 	Certificates as to Conditions Precedent	  	 	49	  
				
		 	Section 13.08	 	Payments on Business Days	  	 	49	  
				
		 	Section 13.09	 	Conflict with Trust Indenture Act	  	 	49	  

  
 iii.

									
				
		 	Section 13.10	 	Counterparts	  	 	50	  
				
		 	Section 13.11	 	Separability	  	 	50	  
				
		 	Section 13.12	 	Compliance Certificates	  	 	50	  
				
		 	Section 13.13	 	U.S.A Patriot Act	  	 	50	  
				
		 	Section 13.14	 	Force Majeure	  	 	50	  
				
		 	Section 13.15	 	Table of Contents; Headings	  	 	51	  

  

	(1)	This Table of Contents does not constitute part of the Indenture and shall not have any bearing on the interpretation of any of its terms or provisions.

  
 iv.

 INDENTURE 
 INDENTURE, dated as of August 14, 2012, among Exelixis, Inc., a Delaware corporation (the “Company”), and Wells Fargo Bank, National Association, a
national banking association, as trustee (the “Trustee”): 
 WHEREAS, for its
lawful corporate purposes, the Company has duly authorized the execution and delivery of this Indenture to provide for the issuance of debt securities (hereinafter referred to as the “Securities”), in an unlimited aggregate principal
amount to be issued from time to time in one or more series as in this Indenture provided, as registered Securities without coupons, to be authenticated by the certificate of the Trustee; 

WHEREAS, to provide the terms and conditions upon which the Securities are to be authenticated,
issued and delivered, the Company has duly authorized the execution of this Indenture; and 

WHEREAS, all things necessary to make this Indenture a valid agreement of the Company, in accordance
with its terms, have been done. 
 NOW, THEREFORE, in consideration of the
premises and the purchase of the Securities by the holders thereof, it is mutually covenanted and agreed as follows for the equal and ratable benefit of the holders of Securities: 

ARTICLE 1 

DEFINITIONS 
  

	 	Section 1.01	Definitions of Terms. 

The terms defined in this Section (except as in this Indenture or any indenture supplemental hereto otherwise expressly provided or unless
the context otherwise requires) for all purposes of this Indenture and of any indenture supplemental hereto shall have the respective meanings specified in this Section and shall include the plural as well as the singular. All other terms used in
this Indenture that are defined in the Trust Indenture Act of 1939, as amended, or that are by reference in such Act defined in the Securities Act of 1933, as amended (except as herein or any indenture supplemental hereto otherwise expressly
provided or unless the context otherwise requires), shall have the meanings assigned to such terms in said Trust Indenture Act and in said Securities Act as in force at the date of the execution of this instrument. 

“Authenticating Agent” means an authenticating agent with respect to all or any of the series of Securities
appointed by the Trustee pursuant to Section 2.10. 
 “Bankruptcy Law” means Title 11, U.S. Code,
or any similar federal or state law for the relief of debtors. 

  
 1. 

 “Board of Directors” means the Board of Directors (or the functional
equivalent thereof) of the Company or any duly authorized committee of such Board. 
 “Board Resolution”
means a copy of a resolution certified by the Secretary or an Assistant Secretary of the Company to have been duly adopted by the Board of Directors (or duly authorized committee thereof) and to be in full force and effect on the date of such
certification. 
 “Business Day” means, with respect to any series of Securities, any day other than a
day on which federal or state banking institutions in the Borough of Manhattan, the City of New York, or in the city of the Corporate Trust Office of the Trustee, are authorized or obligated by law, executive order or regulation to close.

 “Certificate” means a certificate signed by any Officer. The Certificate need not comply with the
provisions of Section 13.07. 
 “Commission” means the Securities and Exchange Commission, as from
time to time constituted, created under the Exchange Act, or, if at any time after the execution of this instrument such Commission is not existing and performing the duties now assigned to it under the Trust Indenture Act, then the body performing
such duties at such time. 
 “Company” means Exelixis, Inc., a corporation duly organized and existing
under the laws of the State of Delaware, and, subject to the provisions of Article Ten, shall also include its successors and assigns. 
 “Corporate Trust Office” means the office of the Trustee at which, at any particular time, its corporate trust business shall be principally administered, which office at the date
hereof is located at Wells Fargo Bank, National Association, MAC E2818-176, 707 Wilshire Boulevard, 17th Floor, Los Angeles, CA 90017 Attention: Corporate Trust Services, or such other address as the Trustee may designate from time to time by notice to the Securityholders and the Company, or the principal
corporate trust office of any successor Trustee (or such other address as such successor Trustee may designate from time to time by notice to the Securityholders and the Company). 

“Custodian” means any receiver, trustee, assignee, liquidator or similar official under any Bankruptcy Law.

 “Defaulted Interest” has the meaning set forth in Section 2.03. 

“Depositary” means, with respect to Securities of any series for which the Company shall determine that such
Securities will be issued as a Global Security, The Depository Trust Company, another clearing agency, or any successor registered as a clearing agency under the Exchange Act, or other applicable statute or regulation, which, in each case, shall be
designated by the Company pursuant to either Section 2.01 or 2.11. 

  
 2. 

 “Event of Default” means, with respect to Securities of a particular
series, any event specified in Section 6.01, continued for the period of time, if any, therein designated. 

“Exchange Act” means the United States Securities and Exchange Act of 1934, as amended, and the rules and
regulations promulgated by the Commission thereunder. 
 “Global Security” means a Security issued to
evidence all or a part of any series of Securities which is executed by the Company and authenticated and delivered by the Trustee to the Depositary or pursuant to the Depositary’s instruction, all in accordance with the Indenture, which shall
be registered in the name of the Depositary or its nominee. 
 “Governmental Obligations” means
securities that are (a) direct obligations of the United States of America for the payment of which its full faith and credit is pledged or (b) obligations of a Person controlled or supervised by and acting as an agency or instrumentality
of the United States of America, the payment of which is unconditionally guaranteed as a full faith and credit obligation by the United States of America that, in either case, are not callable or redeemable at the option of the issuer thereof at any
time prior to the stated maturity of the Securities, and shall also include a depositary receipt issued by a bank or trust company as custodian with respect to any such Governmental Obligation or a specific payment of principal of or interest on any
such Governmental Obligation held by such custodian for the account of the holder of such depositary receipt; provided, however, that (except as required by law) such custodian is not authorized to make any deduction from the amount payable to the
holder of such depositary receipt from any amount received by the custodian in respect of the Governmental Obligation or the specific payment of principal of or interest on the Governmental Obligation evidenced by such depositary receipt.

 “herein”, “hereof” and “hereunder”, and other
words of similar import, refer to this Indenture as a whole and not to any particular Article, Section or other subdivision. 

“Indenture” means this instrument as originally executed or as it may from time to time be supplemented or
amended by one or more indentures supplemental hereto entered into in accordance with the terms hereof and shall include the terms of particular series of Securities established as contemplated by Section 2.01. 

“Interest Payment Date”, when used with respect to any installment of interest on a Security of a particular
series, means the date specified in such Security or in a Board Resolution or in an indenture supplemental hereto with respect to such series as the fixed date on which an installment of interest with respect to Securities of that series is due and
payable. 
 “Officer” means, with respect to the Company, the chairman of the Board of Directors, the
chief executive officer, the president, the chief financial officer, the chief operating officer, any executive vice president, any senior vice president, any vice president, the treasurer or any assistant treasurer, the controller or any assistant
controller or the secretary or any assistant secretary. 

  
 3. 

 “Officer’s Certificate” means a certificate signed by any
Officer. Each such certificate shall include the statements provided for in Section 13.07(b), if and to the extent required by the provisions thereof. 
 “Opinion of Counsel” means an opinion in writing subject to customary exceptions of legal counsel, who may be an employee of or counsel for the Company, that is delivered to the
Trustee in accordance with the terms hereof. Each such opinion shall include the statements provided for in Section 13.07(b), if and to the extent required by the provisions thereof. 

“Outstanding”, when used with reference to Securities of any series, means, subject to the provisions of
Section 8.04, as of any particular time, all Securities of that series theretofore authenticated and delivered by the Trustee under this Indenture, except (a) Securities theretofore canceled by the Trustee or any paying agent, or delivered
to the Trustee or any paying agent for cancellation or that have previously been canceled; (b) Securities or portions thereof for the payment or redemption of which moneys or Governmental Obligations in the necessary amount shall have been
deposited in trust with the Trustee or with any paying agent (other than the Company) or shall have been set aside and segregated in trust by the Company (if the Company shall act as its own paying agent); provided, however, that if such Securities
or portions of such Securities are to be redeemed prior to the maturity thereof, notice of such redemption shall have been given as provided in Article Three, or provision satisfactory to the Trustee shall have been made for giving such notice; and
(c) Securities in lieu of or in substitution for which other Securities shall have been authenticated and delivered pursuant to the terms of Section 2.07. 
 “Person” means any individual, corporation, partnership, joint venture, joint-stock company, limited liability company, association, trust, unincorporated organization, any other
entity or organization, including a government or political subdivision or an agency or instrumentality thereof. 

“Predecessor Security” of any particular Security means every previous Security evidencing all or a portion of
the same debt as that evidenced by such particular Security; and, for the purposes of this definition, any Security authenticated and delivered under Section 2.07 in lieu of a lost, destroyed or stolen Security shall be deemed to evidence the
same debt as the lost, destroyed or stolen Security. 
 “Responsible Officer” when used with respect to
the Trustee means any vice president, any trust officer, any corporate trust officer or any other officer or assistant officer of the Trustee customarily performing functions similar to those performed by the Persons who at the time shall be such
officers, respectively, or to whom any corporate trust matter is referred because of his or her knowledge of and familiarity with the particular subject and who has direct responsibility for the administration of this Indenture. 

“Securities” has the meaning stated in the first recital of this Indenture and more particularly means any
Securities authenticated and delivered under this Indenture. 
 “Securities Act” means the Securities
Act of 1933, as amended. 

  
 4. 

 “Securityholder”, “holder of Securities”,
“registered holder”, or other similar term, means the Person or Persons in whose name or names a particular Security is registered on the Security Register kept for that purpose in accordance with the terms of this Indenture.

 “Security Register” and “Security Registrar” shall have the meanings as set
forth in Section 2.05. 
 “Subsidiary” means, with respect to any Person: 

(1) any corporation or company a majority of whose capital stock with voting power, under ordinary circumstances, to
elect directors is, at the date of determination, directly or indirectly, owned by such Person (a “subsidiary”), by one or more subsidiaries of such Person or by such Person and one or more subsidiaries of such Person;

 (2) a partnership in which such Person or a subsidiary of such Person is, at the date of determination, a
general partner of such partnership; or 
 (3) any partnership, limited liability company or other Person in
which such Person, a subsidiary of such Person or such Person and one or more subsidiaries of such Person, directly or indirectly, at the date of determination, have (x) at least a majority ownership interest or (y) the power to elect or
appoint or direct the election or appointment of the managing partner or member of such Person or, if applicable, a majority of the directors or other governing body of such Person. 

“Trustee” means Wells Fargo Bank, National Association, and, subject to the provisions of Article Seven, shall
also include its successors and assigns, and, if at any time there is more than one Person acting in such capacity hereunder, “Trustee” shall mean each such Person. The term “Trustee” as used with respect to a particular series
of the Securities shall mean the trustee with respect to that series. 
 “Trust Indenture Act” means the
Trust Indenture Act of 1939, as amended. 
 “U.S.A. Patriot Act” means the Uniting and Strengthening
America by Providing Appropriate Tools Required to Intercept and Obstruct Terrorism Act of 2001, Pub. L. 107-56, as amended and signed into law October 26, 2001. 

  
 5. 

 ARTICLE 2 
 ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 
  

	 	Section 2.01	Designation and Terms of Securities. 

 (a) The aggregate principal amount of Securities that may be authenticated and delivered under this Indenture is unlimited. The Securities may be issued in one or more series up to the aggregate
principal amount of Securities of that series from time to time authorized by or pursuant to a Board Resolution or pursuant to one or more indentures supplemental hereto. Prior to the initial issuance of Securities of any series, there shall be
established in or pursuant to a Board Resolution, and set forth in an Officer’s Certificate, or established in one or more indentures supplemental hereto: 
 (1) the title of the Securities of the series (which shall distinguish the Securities of that series from all other Securities); 

(2) any limit upon the aggregate principal amount of the Securities of that series that may be authenticated and delivered under
this Indenture (except for Securities authenticated and delivered upon registration of transfer of, or in exchange for, or in lieu of, other Securities of that series); 
 (3) the maturity date or dates on which the principal of the Securities of the series is payable; 
 (4) the form of the Securities of the series including the form of the certificate of authentication for such series; 
 (5) the applicability of any guarantees; 
 (6) whether or not the
Securities will be secured or unsecured, and the terms of any secured debt; 
 (7) whether the Securities rank as senior
debt, senior subordinated debt, subordinated debt or any combination thereof, and the terms of any subordination; 
 (8)
if the price (expressed as a percentage of the aggregate principal amount thereof) at which such Securities will be issued is a price other than the principal amount thereof, the portion of the principal amount thereof payable upon declaration
of acceleration of the maturity thereof, or if applicable, the portion of the principal amount of such Securities that is convertible into another security or the method by which any such portion shall be determined; 

(9) the interest rate or rates, which may be fixed or variable, or the method for determining the rate and the date interest will
begin to accrue, the dates interest will be 

  
 6. 

 
payable and the regular record dates for interest payment dates or the method for determining such dates; 
 (10) the Company’s right, if any, to defer the payment of interest and the maximum length of any such deferral period; 

(11) if applicable, the date or dates after which, or the period or periods during which, and the price or prices at which, the
Company may at its option, redeem the series of Securities pursuant to any optional or provisional redemption provisions and the terms of those redemption provisions; 
 (12) the date or dates, if any, on which, and the price or prices at which the Company is obligated, pursuant to any mandatory sinking fund or analogous fund provisions or otherwise, to redeem, or
at the Securityholder’s option to purchase, the series of Securities and the currency or currency unit in which the Securities are payable; 
 (13) the denominations in which the Securities of the series shall be issuable, if other than denominations of one thousand U.S. dollars ($1,000) or any integral multiple thereof; 

(14) any and all terms, if applicable, relating to any auction or remarketing of the Securities of that series and any security
for the obligations of the Company with respect to such Securities and any other terms which may be advisable in connection with the marketing of Securities of that series; 
 (15) whether the Securities of the series shall be issued in whole or in part in the form of a Global Security or Securities; the terms and conditions, if any, upon which such Global Security or
Securities may be exchanged in whole or in part for other individual Securities; and the Depositary for such Global Security or Securities; 
 (16) if applicable, the provisions relating to conversion or exchange of any Securities of the series and the terms and conditions upon which such Securities will be so convertible or exchangeable,
including the conversion or exchange price, as applicable, or how it will be calculated and may be adjusted, any mandatory or optional (at the Company’s option or the holders’ option) conversion or exchange features, the applicable
conversion or exchange period and the manner of settlement for any conversion or exchange, which may, without limitation, include the payment of cash as well as the delivery of securities; 

(17) if other than the full principal amount thereof, the portion of the principal amount of Securities of the series which shall
be payable upon declaration of acceleration of the maturity thereof pursuant to Section 6.01; 
 (18) additions to
or changes in the covenants applicable to the series of Securities being issued, including, among others, the consolidation, merger or sale covenant; 

  
 7. 

 (19) additions to or changes in the Events of Default with respect to the Securities
and any change in the right of the Trustee or the Securityholders to declare the principal, premium, if any, and interest, if any, with respect to such Securities to be due and payable; 

(20) additions to or changes in or deletions of the provisions relating to covenant defeasance and legal defeasance; 

(21) additions to or changes in the provisions relating to satisfaction and discharge of this Indenture; 

(22) additions to or changes in the provisions relating to the modification of this Indenture both with and without the consent
of Securityholders of Securities issued under this Indenture; 
 (23) the currency of payment of Securities if other
than U.S. dollars and the manner of determining the equivalent amount in U.S. dollars; 
 (24) whether interest will be
payable in cash or additional Securities at the Company’s or the Securityholders’ option, the terms and conditions upon which the election may be made; 
 (25) the terms and conditions, if any, upon which the Company shall pay amounts in addition to the stated interest, premium, if any and principal amounts of the Securities of the series to any
Securityholder that is not a “United States person” for federal tax purposes; 
 (26) any restrictions on
transfer, sale or assignment of the Securities of the series; and 
 (27) any other specific terms, preferences, rights
or limitations of, or restrictions on, the Securities, any other additions or changes in the provisions of this Indenture, and any terms that may be required by us or advisable under applicable laws or regulations. 

(b) All Securities of any one series shall be substantially identical except as may otherwise be provided in or pursuant to any
such Board Resolution or in any indentures supplemental hereto. 
 If any of the terms of the series are established by action
taken pursuant to a Board Resolution of the Company, a copy of an appropriate record of such action shall be certified by the secretary or an assistant secretary of the Company and delivered to the Trustee at or prior to the delivery of the
Officer’s Certificate of the Company setting forth the terms of the series. 
 Securities of any particular series may be
issued at various times, with different dates on which the principal or any installment of principal is payable, with different rates of interest, if 

  
 8. 

 
any, or different methods by which rates of interest may be determined, with different dates on which such interest may be payable and with different redemption dates. 

 

	 	Section 2.02	Form of Securities and Trustee’s Certificate. 

 The Securities of any series and the Trustee’s certificate of authentication to be borne by such Securities shall be substantially of the tenor and purport as set forth in one or more indentures
supplemental hereto or as provided in a Board Resolution, and set forth in an Officer’s Certificate, and they may have such letters, numbers or other marks of identification or designation and such legends or endorsements printed, lithographed
or engraved thereon as the Company may deem appropriate and as are not inconsistent with the provisions of this Indenture, or as may be required to comply with any law or with any rule or regulation made pursuant thereto or with any rule or
regulation of any securities exchange on which Securities of that series may be listed, or to conform to usage. 
  

	 	Section 2.03	Denominations: Provisions for Payment. 

 The Securities shall be issuable as registered Securities and in the denominations of one thousand U.S. dollars ($1,000) or any integral multiple thereof, subject to Section 2.01(a)(13). The
Securities of a particular series shall bear interest payable on the dates and at the rate specified with respect to that series. Subject to Section 2.01(a)(23), the principal of and the interest on the Securities of any series, as well as any
premium thereon in the case of a redemption or repurchase thereof prior to maturity, and any cash amount due upon the conversion or exchange thereof, shall be payable in the coin or currency of the United States of America that at the time is legal
tender for public and private debt, at the office or agency of the Company in the continental United States of America maintained for that purpose. Each Security shall be dated the date of its authentication. Interest on the Securities shall be
computed on the basis of a 360-day year composed of twelve 30-day months. 
 The interest installment on any Security that is
payable, and is punctually paid or duly provided for, on any Interest Payment Date for Securities of that series shall be paid to the Person in whose name said Security (or one or more Predecessor Securities) is registered at the close of business
on the regular record date for such interest installment. In the event that any Security of a particular series or portion thereof is called for redemption and the redemption date is subsequent to a regular record date with respect to any Interest
Payment Date and prior to such Interest Payment Date, interest on such Security will be paid upon presentation and surrender of such Security as provided in Section 3.03. 
 Any interest on any Security that is payable, but is not punctually paid or duly provided for, on any Interest Payment Date for Securities of the same series (herein called “Defaulted Interest”)
shall forthwith cease to be payable to the registered holder on the relevant regular record date by virtue of having been such holder; and such Defaulted Interest shall be paid by the Company, at its election, as provided in clause (1) or
clause (2) below: 

  
 9. 

 (1) The Company may make payment of any Defaulted Interest on Securities to the
Persons in whose names such Securities (or their respective Predecessor Securities) are registered at the close of business on a special record date for the payment of such Defaulted Interest, which shall be fixed in the following manner: the
Company shall notify the Trustee in writing of the amount of Defaulted Interest proposed to be paid on each such Security and the date of the proposed payment, and at the same time the Company shall deposit with the Trustee an amount of money equal
to the aggregate amount proposed to be paid in respect of such Defaulted Interest or shall make arrangements satisfactory to the Trustee for such deposit prior to the date of the proposed payment, such money when deposited to be held in trust for
the benefit of the Persons entitled to such Defaulted Interest as in this clause provided. Thereupon the Trustee shall fix a special record date for the payment of such Defaulted Interest which shall not be more than 15 nor less than 10 days prior
to the date of the proposed payment and not less than 10 days after the receipt by the Trustee of the notice of the proposed payment. The Trustee shall promptly notify the Company of such special record date and, in the name and at the expense of
the Company, shall cause notice of the proposed payment of such Defaulted Interest and the special record date therefor to be mailed, first class postage prepaid, to each Securityholder at his or her address as it appears in the Security Register
(as hereinafter defined), not less than 10 days prior to such special record date. Notice of the proposed payment of such Defaulted Interest and the special record date therefor having been mailed as aforesaid, such Defaulted Interest shall be paid
to the Persons in whose names such Securities (or their respective Predecessor Securities) are registered on such special record date. 
 (2) The Company may make payment of any Defaulted Interest on any Securities in any other lawful manner not inconsistent with the requirements of any securities exchange on which such Securities
may be listed, and upon such notice as may be required by such exchange, if, after notice given by the Company to the Trustee of the proposed payment pursuant to this clause, such manner of payment shall be deemed practicable by the Trustee.

 Unless otherwise set forth in a Board Resolution or one or more indentures supplemental hereto establishing the terms of any
series of Securities pursuant to Section 2.01 hereof, the term “regular record date” as used in this Section with respect to a series of Securities and any Interest Payment Date for such series shall mean either the fifteenth day of
the month immediately preceding the month in which an Interest Payment Date established for such series pursuant to Section 2.01 hereof shall occur, if such Interest Payment Date is the first day of a month, or the first day of the month in
which an Interest Payment Date established for such series pursuant to Section 2.01 hereof shall occur, if such Interest Payment Date is the fifteenth day of a month, whether or not such date is a Business Day. 

Subject to the foregoing provisions of this Section, each Security of a series delivered under this Indenture upon transfer of or in
exchange for or in lieu of any other Security of such series shall carry the rights to interest accrued and unpaid, and to accrue, that were carried by such other Security. 

  
 10.

	 	Section 2.04	Execution and Authentications. 

 The Securities shall be signed on behalf of the Company by one of its Officers. Signatures may be in the form of a manual or facsimile signature. 

The Company may use the facsimile signature of any Person who shall have been an Officer (at the time of execution), notwithstanding the
fact that at the time the Securities shall be authenticated and delivered or disposed of such Person shall have ceased to be such an officer of the Company. The Securities may contain such notations, legends or endorsements required by law, stock
exchange rule or usage. Each Security shall be dated the date of its authentication by the Trustee. 
 A Security shall not be
valid until authenticated manually by an authorized signatory of the Trustee, or by an Authenticating Agent. Such signature shall be conclusive evidence that the Security so authenticated has been duly authenticated and delivered hereunder and that
the holder is entitled to the benefits of this Indenture. At any time and from time to time after the execution and delivery of this Indenture, the Company may deliver Securities of any series executed by the Company to the Trustee for
authentication, together with a written order of the Company for the authentication and delivery of such Securities, signed by an Officer, and the Trustee in accordance with such written order shall authenticate and deliver such Securities.

 Upon the Company’s delivery of any such authentication order to the Trustee at any time after the initial issuance of
Securities under this Indenture, the Trustee shall be provided with, and (subject to Sections 315(a) through 315(d) of the Trust Indenture Act) shall be fully protected in conclusively relying upon, (1) an Opinion of Counsel or reliance letter
and (2) an Officer’s Certificate stating that all conditions precedent to the execution, authentication and delivery of such Securities are in conformity with the provisions of this Indenture. 

The Trustee shall not be required to authenticate such Securities if the issue of such Securities pursuant to this Indenture will affect
the Trustee’s own rights, duties or immunities under the Securities and this Indenture or otherwise in a manner that is not reasonably acceptable to the Trustee. 
  

	 	Section 2.05	Registration of Transfer and Exchange. 

 (a) Securities of any series may be exchanged upon presentation thereof at the office or agency of the Company in the continental United States of America designated for such purpose, for other
Securities of such series of authorized denominations, and for a like aggregate principal amount, upon payment of a sum sufficient to cover any tax or other governmental charge in relation thereto, all as provided in this Section. In respect of any
Securities so surrendered for exchange, the Company shall execute, the Trustee shall authenticate and such office or agency shall deliver in exchange therefor the Security or Securities of the same series that the Securityholder making the exchange
shall be entitled to receive, bearing numbers not contemporaneously outstanding. 

  
 11.

 (b) The Company shall keep, or cause to be kept at its office or agency in the
continental United States of America designated for such purpose a register or registers (herein referred to as the “Security Register”) in which, subject to such reasonable regulations as it may prescribe, the Company shall register the
Securities and the transfers of Securities as in this Article provided and which at all reasonable times shall be open for inspection by the Trustee. The registrar for the purpose of registering Securities and transfer of Securities as herein
provided shall be appointed as authorized by Board Resolution (the “Security Registrar”). 
 Upon surrender for
transfer of any Security at the office or agency of the Company designated for such purpose, the Company shall execute, the Trustee shall authenticate and such office or agency shall deliver in the name of the transferee or transferees a new
Security or Securities of the same series as the Security presented for a like aggregate principal amount. 
 All Securities
presented or surrendered for exchange or registration of transfer, as provided in this Section, shall be accompanied (if so required by the Company or the Security Registrar) by a written instrument or instruments of transfer, in form satisfactory
to the Company or the Security Registrar, duly executed by the registered holder or by such holder’s duly authorized attorney in writing. 
 (c) Except as provided pursuant to Section 2.01 pursuant to a Board Resolution, and set forth in an Officer’s Certificate, or established in one or more indentures supplemental to this
Indenture, no service charge shall be made for any exchange or registration of transfer of Securities, or issue of new Securities in case of partial redemption of any series or repurchase, conversion or exchange of less than the entire principal
amount of a Security, but the Company may require payment of a sum sufficient to cover any tax or other governmental charge in relation thereto, other than exchanges pursuant to Section 2.06, Section 3.03(b) and Section 9.04 not
involving any transfer. 
 (d) The Company shall not be required (i) to issue, exchange or register the transfer of
any Securities during a period beginning at the opening of business 15 days before the day of the mailing of a notice of redemption of less than all the Outstanding Securities of the same series and ending at the close of business on the day of such
mailing, nor (ii) to register the transfer of or exchange any Securities of any series or portions thereof called for redemption or surrendered for repurchase, but not validly withdrawn, other than the unredeemed portion of any such Securities
being redeemed in part or not surrendered for repurchase, as the case may be. The provisions of this Section 2.05 are, with respect to any Global Security, subject to Section 2.11 hereof. 

The Trustee shall have no obligation or duty to monitor, determine or inquire as to compliance with any restrictions on transfer imposed
under this Indenture or under applicable law with respect to any transfer of any interest in any Security (including any transfers between or among depositary participants or beneficial owners of interests in any Global Security) other than to
require delivery of such certificates and other documentation or evidence as are expressly required by, and to do so if and when expressly required by the terms of, this Indenture, and to 

  
 12.

 
examine the same to determine substantial compliance as to form with the express requirements hereof. 
 Neither the Trustee nor any agent thereof shall have any responsibility or liability for any actions taken or not taken by the Depositary. 

 

	 	Section 2.06	Temporary Securities. 

Pending the preparation of definitive Securities of any series, the Company may execute, and the Trustee shall authenticate and deliver,
temporary Securities (printed, lithographed or typewritten) of any authorized denomination. Such temporary Securities shall be substantially in the form of the definitive Securities in lieu of which they are issued, but with such omissions,
insertions and variations as may be appropriate for temporary Securities, all as may be determined by the Company. Every temporary Security of any series shall be executed by the Company and be authenticated by the Trustee upon the same conditions
and in substantially the same manner, and with like effect, as the definitive Securities of such series. Without unnecessary delay the Company will execute and will furnish definitive Securities of such series and thereupon any or all temporary
Securities of such series may be surrendered in exchange therefor (without charge to the holders), at the office or agency of the Company in the continental United States of America designated for the purpose, and the Trustee shall authenticate and
such office or agency shall deliver in exchange for such temporary Securities an equal aggregate principal amount of definitive Securities of such series, unless the Company advises the Trustee to the effect that definitive Securities need not be
executed and furnished until further notice from the Company. Until so exchanged, the temporary Securities of such series shall be entitled to the same benefits under this Indenture as definitive Securities of such series authenticated and delivered
hereunder. 
  

	 	Section 2.07	Mutilated, Destroyed, Lost or Stolen Securities. 

 In case any temporary or definitive Security shall become mutilated or be destroyed, lost or stolen, the Company (subject to the next succeeding sentence) shall execute, and upon the Company’s
request the Trustee (subject as aforesaid) shall authenticate and deliver, a new Security of the same series, bearing a number not contemporaneously outstanding, in exchange and substitution for the mutilated Security, or in lieu of and in
substitution for the Security so destroyed, lost or stolen. In every case the applicant for a substituted Security shall furnish to the Company and the Trustee such security or indemnity as may be required by them to save each of them harmless, and,
in every case of destruction, loss or theft, the applicant shall also furnish to the Company and the Trustee evidence to their satisfaction of the destruction, loss or theft of the applicant’s Security and of the ownership thereof. The Trustee
may authenticate any such substituted Security and deliver the same upon the written request or authorization of any officer of the Company. Upon the issuance of any substituted Security, the Company may require the payment of a sum sufficient to
cover any tax or other governmental charge that may be imposed in relation thereto and any other expenses (including the fees and expenses of the Trustee) connected therewith. 

  
 13.

 In case any Security that has matured or is about to mature shall become mutilated or be
destroyed, lost or stolen, the Company may, instead of issuing a substitute Security, pay or authorize the payment of the same (without surrender thereof except in the case of a mutilated Security) if the applicant for such payment shall furnish to
the Company and the Trustee such security or indemnity as they may require to save them harmless, and, in case of destruction, loss or theft, evidence to the satisfaction of the Company and the Trustee of the destruction, loss or theft of such
Security and of the ownership thereof. 
 Every replacement Security issued pursuant to the provisions of this Section shall
constitute an additional contractual obligation of the Company whether or not the mutilated, destroyed, lost or stolen Security shall be found at any time, or be enforceable by anyone, and shall be entitled to all the benefits of this Indenture
equally and proportionately with any and all other Securities of the same series duly issued hereunder. All Securities shall be held and owned upon the express condition that the foregoing provisions are exclusive with respect to the replacement or
payment of mutilated, destroyed, lost or stolen Securities, and shall preclude (to the extent lawful) any and all other rights or remedies, notwithstanding any law or statute existing or hereafter enacted to the contrary with respect to the
replacement or payment of negotiable instruments or other securities without their surrender. 
  

	 	Section 2.08	Cancellation. 

 All
Securities surrendered for the purpose of payment, redemption, repurchase, exchange, registration of transfer or conversion or exchange shall, if surrendered to the Company or any paying agent (or any other applicable agent), be delivered to the
Trustee for cancellation, or, if surrendered to the Trustee, shall be cancelled by it, and no Securities shall be issued in lieu thereof except as expressly required or permitted by any of the provisions of this Indenture. On written request of the
Company at the time of such surrender, the Trustee shall deliver to the Company canceled Securities held by the Trustee. In the absence of such request the Trustee may dispose of canceled Securities in accordance with its standard procedures and
deliver a certificate of disposition to the Company. If the Company shall otherwise acquire any of the Securities, however, such acquisition shall not operate as a redemption or satisfaction of the indebtedness represented by such Securities unless
and until the same are delivered to the Trustee for cancellation. 
  

	 	Section 2.09	Benefits of Indenture. 

Nothing in this Indenture or in the Securities, express or implied, shall give or be construed to give to any Person, other than the
parties hereto and the holders of the Securities, any legal or equitable right, remedy or claim under or in respect of this Indenture, or under any covenant, condition or provision herein contained; all such covenants, conditions and provisions
being for the sole benefit of the parties hereto and of the holders of the Securities. 

  
 14.

	 	Section 2.10	Authenticating Agent. 

 So
long as any of the Securities of any series remain Outstanding there may be an Authenticating Agent for any or all such series of Securities which the Trustee shall have the right to appoint. Said Authenticating Agent shall be authorized to act on
behalf of the Trustee to authenticate Securities of such series issued upon exchange, transfer or partial redemption, repurchase or conversion thereof, and Securities so authenticated shall be entitled to the benefits of this Indenture and shall be
valid and obligatory for all purposes as if authenticated by the Trustee hereunder. All references in this Indenture to the authentication of Securities by the Trustee shall be deemed to include authentication by an Authenticating Agent for such
series. Each Authenticating Agent shall be acceptable to the Company and shall be a corporation that has a combined capital and surplus, as most recently reported or determined by it, sufficient under the laws of any jurisdiction under which it is
organized or in which it is doing business to conduct a trust business, and that is otherwise authorized under such laws to conduct such business and is subject to supervision or examination by federal or state authorities. If at any time any
Authenticating Agent shall cease to be eligible in accordance with these provisions, it shall resign immediately. 
 Any
Authenticating Agent may at any time resign by giving written notice of resignation to the Trustee and to the Company. The Trustee may at any time (and upon request by the Company shall) terminate the agency of any Authenticating Agent by giving
written notice of termination to such Authenticating Agent and to the Company. Upon resignation, termination or cessation of eligibility of any Authenticating Agent, the Trustee may appoint an eligible successor Authenticating Agent acceptable to
the Company. Any successor Authenticating Agent, upon acceptance of its appointment hereunder, shall become vested with all the rights, powers and duties of its predecessor hereunder as if originally named as an Authenticating Agent pursuant hereto.

  

	 	Section 2.11	Global Securities. 

(a) If the Company shall establish pursuant to Section 2.01 that the Securities of a particular series are to be issued as a
Global Security, then the Company shall execute and the Trustee shall, in accordance with Section 2.04, authenticate and deliver, a Global Security that (i) shall represent, and shall be denominated in an amount equal to the aggregate
principal amount of, all of the Outstanding Securities of such series, (ii) shall be registered in the name of the Depositary or its nominee, (iii) shall be delivered by the Trustee to the Depositary or pursuant to the Depositary’s
instruction (or if the Depositary names the Trustee as its custodian, retained by the Trustee) and (iv) shall bear a legend substantially to the following effect: “Except as otherwise provided in Section 2.11 of the Indenture, this
Security may be transferred, in whole but not in part, only to another nominee of the Depositary or to a successor Depositary or to a nominee of such successor Depositary.” 

(b) Notwithstanding the provisions of Section 2.05, the Global Security of a series may be transferred, in whole but not in
part and in the manner provided in Section 2.05, 

  
 15.

 
only to another nominee of the Depositary for such series, or to a successor Depositary for such series selected or approved by the Company or to a nominee of such successor Depositary.

 (c) If at any time the Depositary for a series of the Securities notifies the Company that it is unwilling or unable
to continue as Depositary for such series or if at any time the Depositary for such series shall no longer be registered or in good standing under the Exchange Act, or other applicable statute or regulation, and a successor Depositary for such
series is not appointed by the Company within 90 days after the Company receives such notice or becomes aware of such condition, as the case may be, or if an Event of Default has occurred and is continuing and the Company has received a request from
the Depositary or from the Trustee, this Section 2.11 shall no longer be applicable to the Securities of such series and the Company will execute, and subject to Section 2.04, the Trustee will authenticate and deliver the Securities of
such series in definitive registered form without coupons, in authorized denominations, and in an aggregate principal amount equal to the principal amount of the Global Security of such series in exchange for such Global Security. In addition, the
Company may at any time determine that the Securities of any series shall no longer be represented by a Global Security and that the provisions of this Section 2.11 shall no longer apply to the Securities of such series. In such event the
Company will execute and, subject to Section 2.04, the Trustee, upon receipt of an Officer’s Certificate evidencing such determination by the Company, will authenticate and deliver the Securities of such series in definitive registered
form without coupons, in authorized denominations, and in an aggregate principal amount equal to the principal amount of the Global Security of such series in exchange for such Global Security. Upon the exchange of the Global Security for such
Securities in definitive registered form without coupons, in authorized denominations, the Global Security shall be canceled by the Trustee. Such Securities in definitive registered form issued in exchange for the Global Security pursuant to this
Section 2.11(c) shall be registered in such names and in such authorized denominations as the Depositary, pursuant to instructions from its direct or indirect participants or otherwise, shall instruct the Trustee. The Trustee shall deliver such
Securities to the Depositary for delivery to the Persons in whose names such Securities are so registered. 
  

	 	Section 2.12	CUSIP Numbers. 

 The
Company in issuing the Securities may use “CUSIP” numbers (if then generally in use), and, if so, the Trustee shall use “CUSIP” numbers in notices of redemption as a convenience to Securityholders; provided that any such notice
may state that no representation is made as to the correctness of such numbers either as printed on the Securities or as contained in any notice of a redemption and that reliance may be placed only on the other identification numbers printed on the
Securities, and any such redemption shall not be affected by any defect in or omission of such numbers. The Company will promptly notify the Trustee in writing of any change in the “CUSIP” numbers. 

  
 16.

 ARTICLE 3 
 REDEMPTION OF SECURITIES AND SINKING FUND PROVISIONS 
  

	 	Section 3.01	Redemption. 

 The Company
may redeem the Securities of any series issued hereunder on and after the dates and in accordance with the terms established for such series pursuant to Section 2.01 hereof. 

 

	 	Section 3.02	Notice of Redemption. 

(a) In case the Company shall desire to exercise such right to redeem all or, as the case may be, a portion of the Securities of
any series in accordance with any right the Company reserved for itself to do so pursuant to Section 2.01 hereof, the Company shall, or shall cause the Trustee to, give notice of such redemption to holders of the Securities of such series to be
redeemed by mailing, first class postage prepaid (or with regard to any Global Security held in book entry form, by electronic mail), a notice of such redemption not less than 30 days and not more than 60 days before the date fixed for redemption of
that series to such holders at their last addresses as they shall appear upon the Security Register, unless a shorter period is specified in the Securities to be redeemed. Any notice that is mailed in the manner herein provided shall be conclusively
presumed to have been duly given, whether or not the registered holder receives the notice. In any case, failure duly to give such notice to the holder of any Security of any series designated for redemption in whole or in part, or any defect in the
notice, shall not affect the validity of the proceedings for the redemption of any other Securities of such series or any other series. In the case of any redemption of Securities prior to the expiration of any restriction on such redemption
provided in the terms of such Securities or elsewhere in this Indenture, the Company shall furnish the Trustee with an Officer’s Certificate evidencing compliance with any such restriction. 

Each such notice of redemption shall identify the Securities to be redeemed (including CUSIP number(s)), specify the date fixed for
redemption and the redemption price at which Securities of that series are to be redeemed, and shall state that payment of the redemption price of such Securities to be redeemed will be made at the office or agency of the Company in the continental
United States of America, upon presentation and surrender of such Securities, that interest accrued to the date fixed for redemption will be paid as specified in said notice, that from and after said date interest will cease to accrue and that the
redemption is from a sinking fund, if such is the case. If less than all the Securities of a series are to be redeemed, the notice to the holders of Securities of that series to be redeemed in part shall specify the particular Securities to be so
redeemed. 
 In case any Security is to be redeemed in part only, the notice that relates to such Security shall state the
portion of the principal amount thereof to be redeemed, and shall state that on and after the redemption date, upon surrender of such Security, a new Security or Securities of such series in principal amount equal to the unredeemed portion thereof
will be issued. 

  
 17.

 (b) If less than all the Securities of a series are to be redeemed, the Company shall
give the Trustee at least 45 days’ notice (unless a shorter notice shall be satisfactory to the Trustee) in advance of the date fixed for redemption as to the aggregate principal amount of Securities of the series to be redeemed, and thereupon
the Trustee shall select, by lot or in such other manner as it shall deem appropriate and fair in its discretion and that may provide for the selection of a portion or portions (equal to one thousand U.S. dollars ($1,000) or any integral multiple
thereof) of the principal amount of such Securities of a denomination larger than $1,000, the Securities to be redeemed and shall thereafter promptly notify the Company in writing of the numbers of the Securities to be redeemed, in whole or in part.
The Company may, if and whenever it shall so elect, by delivery of instructions signed on its behalf by an Officer, instruct the Trustee or any paying agent to call all or any part of the Securities of a particular series for redemption and to give
notice of redemption in the manner set forth in this Section, such notice to be in the name of the Company or its own name as the Trustee or such paying agent may deem advisable. In any case in which notice of redemption is to be given by the
Trustee or any such paying agent, the Company shall so notify the Trustee at least 15 days before notice is required to be given to Holders (unless a shorter notice shall be satisfactory to the Trustee) and shall deliver or cause to be delivered to,
or permit to remain with, the Trustee or such paying agent, as the case may be, such Security Register, transfer books or other records, or suitable copies or extracts therefrom, sufficient to enable the Trustee or such paying agent to give any
notice by mail that may be required under the provisions of this Section. 
  

	 	Section 3.03	Payment Upon Redemption. 

(a) If the giving of notice of redemption shall have been completed as above provided, the Securities or portions of Securities of
the series to be redeemed specified in such notice shall become due and payable on the date and at the place stated in such notice at the applicable redemption price, together with interest accrued to the date fixed for redemption and interest on
such Securities or portions of Securities shall cease to accrue on and after the date fixed for redemption, unless the Company shall default in the payment of such redemption price and accrued interest with respect to any such Security or portion
thereof. On presentation and surrender of such Securities on or after the date fixed for redemption at the place of payment specified in the notice, said Securities shall be paid and redeemed at the applicable redemption price for such series,
together with interest accrued thereon to the date fixed for redemption (but if the date fixed for redemption is an Interest Payment Date, the interest installment payable on such date shall be payable to the registered holder at the close of
business on the applicable record date pursuant to Section 2.03). 
 (b) Upon presentation of any Security of such
series that is to be redeemed in part only, the Company shall execute and the Trustee shall authenticate and the office or agency where the Security is presented shall deliver to the holder thereof, at the expense of the Company, a new Security of
the same series of authorized denominations in principal amount equal to the unredeemed portion of the Security so presented. 

  
 18.

	 	Section 3.04	Sinking Fund. 

 The
provisions of Sections 3.04, 3.05 and 3.06 shall be applicable to any sinking fund for the retirement of Securities of a series, except as otherwise specified as contemplated by Section 2.01 for Securities of such series. 

The minimum amount of any sinking fund payment provided for by the terms of Securities of any series is herein referred to as a
“mandatory sinking fund payment,” and any payment in excess of such minimum amount provided for by the terms of Securities of any series is herein referred to as an “optional sinking fund payment”. If provided for by the terms of
Securities of any series, the cash amount of any sinking fund payment may be subject to reduction as provided in Section 3.05. Each sinking fund payment shall be applied to the redemption of Securities of any series as provided for by the terms
of Securities of such series. 
  

	 	Section 3.05	Satisfaction of Sinking Fund Payments with Securities. 

 The Company (i) may deliver Outstanding Securities of a series and (ii) may apply as a credit Securities of a series that have been redeemed either at the election of the Company pursuant to the
terms of such Securities or through the application of permitted optional sinking fund payments pursuant to the terms of such Securities, in each case in satisfaction of all or any part of any sinking fund payment with respect to the Securities of
such series required to be made pursuant to the terms of such Securities as provided for by the terms of such series, provided that such Securities have not been previously so credited. Such Securities shall be received and credited for such purpose
by the Trustee at the redemption price specified in such Securities for redemption through operation of the sinking fund and the amount of such sinking fund payment shall be reduced accordingly. 

 

	 	Section 3.06	Redemption of Securities for Sinking Fund. 

 Not less than 45 days prior to each sinking fund payment date for any series of Securities (unless a shorter period shall be satisfactory to the Trustee), the Company will deliver to the Trustee an
Officer’s Certificate specifying the amount of the next ensuing sinking fund payment for that series pursuant to the terms of the series, the portion thereof, if any, that is to be satisfied by delivering and crediting Securities of that series
pursuant to Section 3.05 and the basis for such credit and will, together with such Officer’s Certificate, deliver to the Trustee any Securities to be so delivered. Not less than 30 days before each such sinking fund payment date the
Trustee shall select the Securities to be redeemed upon such sinking fund payment date in the manner specified in Section 3.02 and cause notice of the redemption thereof to be given in the name of and at the expense of the Company in the manner
provided in Section 3.02. Such notice having been duly given, the redemption of such Securities shall be made upon the terms and in the manner stated in Section 3.03. 

  
 19.

 ARTICLE 4 
 COVENANTS 
  

	 	Section 4.01	Payment of Principal, Premium and Interest. 

 The Company will duly and punctually pay or cause to be paid the principal of (and premium, if any), interest on, and any redemption price or repurchase price for the Securities of that series at the time
and place and in the manner provided herein and established with respect to such Securities. Payments of the principal of, redemption price for or repurchase price for, the Securities may be made at the time provided herein and established with
respect to such Securities by U.S. dollar check drawn on and mailed to the address of the Securityholder entitled thereto as such address shall appear in the Security Register, or U.S. dollar wire transfer to, a U.S. dollar account if such
Securityholder shall have furnished wire instructions to the Trustee no later than 15 days prior to the relevant payment date. Payments of interest on the Securities may be made at the time provided herein and established with respect to such
Securities by U.S. dollar check mailed to the address of the Securityholder entitled thereto as such address shall appear in the Security Register, or U.S. dollar wire transfer to, a U.S. dollar account if such Securityholder shall have furnished
wire instructions in writing to the Security Registrar and the Trustee no later than 15 days prior to the relevant payment date. 
  

	 	Section 4.02	Maintenance of Office or Agency. 

 So long as any series of the Securities remain Outstanding, the Company agrees to maintain an office or agency in the continental United States of America with respect to each such series and at such
other location or locations as may be designated as provided in this Section 4.02, where (i) Securities of that series may be presented for payment, (ii) Securities of that series may be presented as herein above authorized for
registration of transfer and exchange, and (iii) notices and demands to or upon the Company in respect of the Securities of that series and this Indenture may be given or served, such designation to continue with respect to such office or
agency until the Company shall, by written notice signed by any officer authorized to sign an Officer’s Certificate and delivered to the Trustee, designate some other office or agency for such purposes or any of them. If at any time the Company
shall fail to maintain any such required office or agency or shall fail to furnish the Trustee with the address thereof, such presentations, notices and demands may be made or served at the Corporate Trust Office of the Trustee, and the Company
hereby appoints the Trustee as its agent to receive all such presentations, notices and demands. The Company initially appoints the Trustee as its paying agent with respect to the Securities. 

 

	 	Section 4.03	Paying Agents. 

 (a)
If the Company shall appoint one or more paying agents for all or any series of the Securities, other than the Trustee, the Company will cause each such paying agent to execute and deliver to the Trustee an instrument in which such agent shall
agree with the Trustee, subject to the provisions of this Section: 

  
 20.

 (1) that it will hold all sums held by it as such agent for the payment of the
principal of (and premium, if any) or interest on the Securities of that series (whether such sums have been paid to it by the Company or by any other obligor of such Securities) in trust for the benefit of the Persons entitled thereto; 

(2) that it will give the Trustee notice of any failure by the Company (or by any other obligor of such Securities) to make any
payment of the principal of (and premium, if any) or interest on the Securities of that series when the same shall be due and payable; 
 (3) that it will, at any time during the continuance of any failure referred to in the preceding paragraph (a)(2) above, upon the written request of the Trustee, forthwith pay to the Trustee all
sums so held in trust by such paying agent; and 
 (4) that it will perform all other duties of paying agent as set
forth in this Indenture. 
 (b) If the Company shall act as its own paying agent with respect to any series of the
Securities, it will on or before each due date of the principal of (and premium, if any) or interest on Securities of that series, set aside, segregate and hold in trust for the benefit of the Persons entitled thereto a sum sufficient to pay such
principal (and premium, if any) or interest so becoming due on Securities of that series until such sums shall be paid to such Persons or otherwise disposed of as herein provided and will promptly notify the Trustee of such action, or any failure
(by it or any other obligor on such Securities) to take such action. Whenever the Company shall have one or more paying agents for any series of Securities, it will, prior to each due date of the principal of (and premium, if any) or interest on any
Securities of that series, deposit with the paying agent a sum sufficient to pay the principal (and premium, if any) or interest so becoming due, such sum to be held in trust for the benefit of the Persons entitled to such principal, premium or
interest, and (unless such paying agent is the Trustee) the Company will promptly notify the Trustee of this action or failure so to act. 
 (c) Notwithstanding anything in this Section to the contrary, (i) the agreement to hold sums in trust as provided in this Section is subject to the provisions of Section 11.05, and
(ii) the Company may at any time, for the purpose of obtaining the satisfaction and discharge of this Indenture or for any other purpose, pay, or direct any paying agent to pay, to the Trustee all sums held in trust by the Company or such
paying agent, such sums to be held by the Trustee upon the same terms and conditions as those upon which such sums were held by the Company or such paying agent; and, upon such payment by the Company or any paying agent to the Trustee, the Company
or such paying agent shall be released from all further liability with respect to such money. 
  

	 	Section 4.04	Appointment to Fill Vacancy in Office of Trustee. 

 The Company, whenever necessary to avoid or fill a vacancy in the office of Trustee, will appoint, in the manner provided in Section 7.10, a Trustee, so that there shall at all times be a Trustee
hereunder. 

  
 21.

	 	Section 4.05	Compliance with Consolidation Provisions. 

 The Company will not, while any of the Securities remain Outstanding, consolidate with or merge into any other Person, in either case where the Company is not the survivor of such transaction, or sell or
convey all or substantially all of its property to any other Person unless the provisions of Article Ten hereof are complied with. 
 ARTICLE 5 
 SECURITYHOLDERS’ LISTS AND REPORTS BY THE COMPANY AND
THE TRUSTEE 
  

	 	Section 5.01	Company to Furnish Trustee Names and Addresses of Securityholders. 

 The Company will furnish or cause to be furnished to the Trustee (a) within 15 days after each regular record date (as defined in Section 2.03) a list, in such form as the Trustee may reasonably
require, of the names and addresses of the holders of each series of Securities as of such regular record date, provided that the Company shall not be obligated to furnish or cause to furnish such list at any time that the list shall not differ in
any respect from the most recent list furnished to the Trustee by the Company and (b) at such other times as the Trustee may request in writing within 30 days after the receipt by the Company of any such request, a list of similar form and
content as of a date not more than 15 days prior to the time such list is furnished; provided, however, that, in either case, no such list need be furnished for any series for which the Trustee shall be the Security Registrar. 

 

	 	Section 5.02	Preservation Of Information; Communications With Securityholders. 

 (a) The Trustee shall preserve, in as current a form as is reasonably practicable, all information as to the names and addresses of the holders of Securities contained in the most recent list
furnished to it as provided in Section 5.01 and as to the names and addresses of holders of Securities received by the Trustee in its capacity as Security Registrar (if acting in such capacity). 

(b) The Trustee may destroy any list furnished to it as provided in Section 5.01 upon receipt of a new list so furnished.

 (c) Securityholders may communicate as provided in Section 312(b) of the Trust Indenture Act with other
Securityholders with respect to their rights under this Indenture or under the Securities, and, in connection with any such communications, the Trustee shall satisfy its obligations under Section 312(b) of the Trust Indenture Act in accordance
with the provisions of Section 312(b) of the Trust Indenture Act. 

  
 22.

	 	Section 5.03	Reports by the Company. 

(a) The Company covenants and agrees to provide (which delivery may be via electronic mail) to the Trustee within 30 days, after
the Company files the same with the Commission, copies of the annual reports and of the information, documents and other reports (or copies of such portions of any of the foregoing as the Commission may from time to time by rules and regulations
prescribe) that the Company is required to file with the Commission pursuant to Section 13 or Section 15(d) of the Exchange Act; provided, however, the Company shall not be required to deliver to the Trustee any correspondence filed with
the SEC or any materials for which the Company has sought and received confidential treatment by the Commission; and provided further, that so long as such filings by the Company are available on the Commission’s Electronic Data Gathering,
Analysis and Retrieval System (EDGAR), or any successor system, such filings shall be deemed to have been filed with the Trustee for purposes hereof without any further action required by the Company, provided, however, that the Trustee shall
have no obligation whatsoever to determine if such filing has been so made. For the avoidance of doubt, a failure by the Company to file annual reports, information and other reports with the SEC within the time period prescribed thereof by the
Commission shall not be deemed a breach of this Section 5.03. 
 (b) Delivery of reports, information and documents
to the Trustee under Section 5.03 is for informational purposes only and the information and the Trustee’s receipt of the foregoing shall not constitute constructive notice of any information contained therein, or determinable from
information contained therein including the Company’s compliance with any of their covenants thereunder (as to which the Trustee is entitled to rely exclusively on an Officer’s Certificate). 

 

	 	Section 5.04	Reports by the Trustee. 

(a) If required by Section 313(a) of the Trust Indenture Act, the Trustee, within sixty (60) days after each
March 15, commencing March 15, 2013, shall transmit by mail, first class postage prepaid, to the Securityholders, as their names and addresses appear upon the Security Register, a brief report dated as of such March 15, which complies
with Section 313(a) of the Trust Indenture Act. 
 (b) The Trustee shall comply with Section 313(b) and 313(c)
of the Trust Indenture Act. 
 (c) A copy of each such report shall, at the time of such transmission to Securityholders,
be filed by the Trustee with the Company, with each securities exchange upon which any Securities are listed (if so listed) and also with the Commission. The Company agrees to promptly notify the Trustee in writing when any Securities become listed
on any securities exchanges and of any delisting thereof. 
 ARTICLE 6 

  
 23.

 REMEDIES OF THE TRUSTEE AND SECURITYHOLDERS ON EVENT OF DEFAULT 

 

	 	Section 6.01	Events of Default. 

(a) Whenever used herein with respect to Securities of a particular series, “Event of Default” means any one or more of
the following events that has occurred and is continuing: 
 (1) the Company defaults in the payment of any installment
of interest upon any of the Securities of that series, as and when the same shall become due and payable, and such default continues for a period of 90 days; provided, however, that a valid extension of an interest payment period by the Company in
accordance with the terms of any indenture supplemental hereto shall not constitute a default in the payment of interest for this purpose; 
 (2) the Company defaults in the payment of the principal of (or premium, if any, on) any of the Securities of that series as and when the same shall become due and payable whether at maturity, upon
redemption, by declaration or otherwise, or in any payment required by any sinking or analogous fund established with respect to that series; provided, however, that a valid extension of the maturity of such Securities in accordance with the terms
of any indenture supplemental hereto shall not constitute a default in the payment of principal or premium, if any; 
 (3)
the Company fails to observe or perform any other of its covenants or agreements with respect to that series contained in this Indenture or otherwise established with respect to that series of Securities pursuant to Section 2.01 hereof
(other than a covenant or agreement that has been expressly included in this Indenture solely for the benefit of one or more series of Securities other than such series) for a period of 90 days after the date on which written notice of such failure,
requiring the same to be remedied and stating that such notice is a “Notice of Default” hereunder, shall have been given to the Company by the Trustee, by registered or certified mail, or to the Company and the Trustee by the holders of at
least 25% in principal amount of the Securities of that series at the time Outstanding; 
 (4) the Company pursuant to
or within the meaning of any Bankruptcy Law (i) commences a voluntary case, (ii) consents to the entry of an order for relief against it in an involuntary case, (iii) consents to the appointment of a Custodian of it or for all or
substantially all of its property or (iv) makes a general assignment for the benefit of its creditors; or 
 (5) a
court of competent jurisdiction enters an order under any Bankruptcy Law that (i) is for relief against the Company in an involuntary case, (ii) appoints a Custodian of the Company for all or substantially all of its property or
(iii) orders the liquidation of the Company, and the order or decree remains unstayed and in effect for 90 days. 
 (b)
In each and every such case (other than an Event of Default specified in clause (4) or clause (5) above), unless the principal of all the Securities of that series shall have 

  
 24.

 
already become due and payable, either the Trustee or the holders of not less than 25% in aggregate principal amount of the Securities of that series then Outstanding hereunder, by notice in
writing to the Company (and to the Trustee if given by such Securityholders), may declare the principal of (and premium, if any, on) and accrued and unpaid interest on all the Securities of that series to be due and payable immediately, and upon any
such declaration the same shall become and shall be immediately due and payable. If an Event of Default specified in clause (4) or clause (5) above occurs, the principal of and accrued and unpaid interest on all the Securities of that
series shall automatically be immediately due and payable without any declaration or other act on the part of the Trustee or the holders of the Securities. 
 (c) At any time after the principal of (and premium, if any, on) and accrued and unpaid interest on the Securities of that series shall have been so declared due and payable, and before any
judgment or decree for the payment of the moneys due shall have been obtained or entered as hereinafter provided, the holders of a majority in aggregate principal amount of the Securities of that series then Outstanding hereunder, by written notice
to the Company and the Trustee, may rescind and annul such declaration and its consequences if: (i) the Company has paid or deposited with the Trustee a sum sufficient to pay all matured installments of interest upon all the Securities of that
series and the principal of (and premium, if any, on) any and all Securities of that series that shall have become due otherwise than by acceleration (with interest upon such principal and premium, if any, and, to the extent that such payment is
enforceable under applicable law, upon overdue installments of interest, at the rate per annum expressed in the Securities of that series to the date of such payment or deposit) and the amount payable to the Trustee under Section 7.06, and
(ii) any and all Events of Default under the Indenture with respect to such series, other than the nonpayment of principal on (and premium, if any, on) and accrued and unpaid interest on Securities of that series that shall not have become due
by their terms, shall have been remedied or waived as provided in Section 6.06. 
 No such rescission and annulment shall
extend to or shall affect any subsequent default or impair any right consequent thereon. 
 (d) In case the Trustee shall
have proceeded to enforce any right with respect to Securities of that series under this Indenture and such proceedings shall have been discontinued or abandoned because of such rescission or annulment or for any other reason or shall have been
determined adversely to the Trustee, then and in every such case, subject to any determination in such proceedings, the Company and the Trustee shall be restored respectively to their former positions and rights hereunder, and all rights, remedies
and powers of the Company and the Trustee shall continue as though no such proceedings had been taken. 
  

	 	Section 6.02	Collection of Indebtedness and Suits for Enforcement by Trustee. 

 (a) The Company covenants that (i) in case it shall default in the payment of any installment of interest on any of the Securities of a series, or in any payment required by any sinking or
analogous fund established with respect to that series as and when the same shall have become due and payable, and such default shall have continued for a period of 90 days, or (ii) in case it shall default in the payment of the principal of
(or premium, if any, on) any of the 

  
 25.

 
Securities of a series when the same shall have become due and payable, whether upon maturity of the Securities of a series or upon redemption or upon declaration or otherwise then, upon demand
of the Trustee, the Company will pay to the Trustee, for the benefit of the holders of the Securities of that series, the whole amount that then shall have been become due and payable on all such Securities for principal (and premium, if any) or
interest, or both, as the case may be, with interest upon the overdue principal (and premium, if any) and (to the extent that payment of such interest is enforceable under applicable law) upon overdue installments of interest at the rate per annum
expressed in the Securities of that series; and, in addition thereto, such further amount as shall be sufficient to cover the costs and expenses of collection, and the amount payable to the Trustee under Section 7.06. 

(b) If the Company shall fail to pay such amounts forthwith upon such demand, the Trustee, in its own name and as trustee of an
express trust, shall be entitled and empowered to institute any action or proceedings at law or in equity for the collection of the sums so due and unpaid, and may prosecute any such action or proceeding to judgment or final decree, and may enforce
any such judgment or final decree against the Company or other obligor upon the Securities of that series and collect the moneys adjudged or decreed to be payable in the manner provided by law or equity out of the property of the Company or other
obligor upon the Securities of that series, wherever situated. 
 (c) In case of any receivership, insolvency,
liquidation, bankruptcy, reorganization, readjustment, arrangement, composition or judicial proceedings affecting the Company, or its creditors or property, the Trustee shall have power to intervene in such proceedings and take any action therein
that may be permitted by the court and shall (except as may be otherwise provided by law) be entitled to file such proofs of claim and other papers and documents as may be necessary or advisable in order to have the claims of the Trustee and of the
holders of Securities of such series allowed for the entire amount due and payable by the Company under the Indenture at the date of institution of such proceedings and for any additional amount that may become due and payable by the Company after
such date, and to collect and receive any moneys or other property payable or deliverable on any such claim, and to distribute the same after the deduction of the amount payable to the Trustee under Section 7.06; and any receiver, assignee or
trustee in bankruptcy or reorganization is hereby authorized by each of the holders of Securities of such series to make such payments to the Trustee, and, in the event that the Trustee shall consent to the making of such payments directly to such
Securityholders, to pay to the Trustee any amount due it under Section 7.06. 
 (d) All rights of action and of
asserting claims under this Indenture, or under any of the terms established with respect to Securities of that series, may be enforced by the Trustee without the possession of any of such Securities, or the production thereof at any trial or other
proceeding relative thereto, and any such suit or proceeding instituted by the Trustee shall be brought in its own name as trustee of an express trust, and any recovery of judgment shall, after provision for payment to the Trustee of any amounts due
under Section 7.06, be for the ratable benefit of the holders of the Securities of such series. 

  
 26.

 In case of an Event of Default hereunder, the Trustee may in its discretion proceed to
protect and enforce the rights vested in it by this Indenture by such appropriate judicial proceedings as the Trustee shall deem most effectual to protect and enforce any of such rights, either at law or in equity or in bankruptcy or otherwise,
whether for the specific enforcement of any covenant or agreement contained in the Indenture or in aid of the exercise of any power granted in this Indenture, or to enforce any other legal or equitable right vested in the Trustee by this Indenture
or by law. 
 Nothing contained herein shall be deemed to authorize the Trustee to authorize or consent to or accept or adopt on
behalf of any Securityholder any plan of reorganization, arrangement, adjustment or composition affecting the Securities of that series or the rights of any holder thereof or to authorize the Trustee to vote in respect of the claim of any
Securityholder in any such proceeding. 
  

	 	Section 6.03	Application of Moneys Collected. 

 Any moneys collected by the Trustee pursuant to this Article with respect to a particular series of Securities shall be applied in the following order, at the date or dates fixed by the Trustee and, in
case of the distribution of such moneys on account of principal (or premium, if any) or interest, upon presentation of the Securities of that series, and notation thereon of the payment, if only partially paid, and upon surrender thereof if fully
paid: 
 FIRST: To the payment of costs and expenses of collection and of all amounts payable to the Trustee under
Section 7.06; 
 SECOND: To the payment of the amounts then due and unpaid upon Securities of such series for principal
(and premium, if any) and interest, in respect of which or for the benefit of which such money has been collected, ratably, without preference or priority of any kind, according to the amounts due and payable on such Securities for principal (and
premium, if any) and interest, respectively; and 
 THIRD: To the payment of the remainder, if any, to the Company or any other
Person lawfully entitled thereto. 
  

	 	Section 6.04	Limitation on Suits. 

 No
holder of any Security of any series shall have any right by virtue or by availing of any provision of this Indenture to institute any suit, action or proceeding in equity or at law upon or under or with respect to this Indenture or for the
appointment of a receiver or trustee, or for any other remedy hereunder, unless (i) such holder previously shall have given to the Trustee written notice of an Event of Default and of the continuance thereof with respect to the Securities of
such series specifying such Event of Default, as hereinbefore provided; (ii) the holders of not less than 25% in aggregate principal amount of the Securities of such series then Outstanding shall have made written request upon the Trustee to
institute such action, suit or proceeding in its own name as Trustee hereunder; (iii) such holder or holders shall have offered to the Trustee 

  
 27.

 
security and indemnity satisfactory to it against the costs, expenses and liabilities to be incurred therein or thereby; (iv) the Trustee for 90 days after its receipt of such notice,
request and offer of indemnity, shall have failed to institute any such action, suit or proceeding and (v) during such 90 day period, the holders of a majority in principal amount of the Securities of that series do not give the Trustee a
direction inconsistent with the request. 
 Notwithstanding anything contained herein to the contrary or any other provisions of
this Indenture, the right of any holder of any Security to receive payment of the principal of (and premium, if any) and interest on such Security, as therein provided, on or after the respective due dates expressed in such Security (or in the case
of redemption, on the redemption date), or to institute suit for the enforcement of any such payment on or after such respective dates or redemption date, shall not be impaired or affected without the consent of such holder and by accepting a
Security hereunder it is expressly understood, intended and covenanted by the taker and holder of every Security of such series with every other such taker and holder and the Trustee, that no one or more holders of Securities of such series shall
have any right in any manner whatsoever by virtue or by availing of any provision of this Indenture to affect, disturb or prejudice the rights of the holders of any other of such Securities, or to obtain or seek to obtain priority over or preference
to any other such holder (it being understood that the Trustee does not have an affirmative duty to ascertain whether or not such actions or forbearances are unduly prejudicial to such Securityholders), or to enforce any right under this Indenture,
except in the manner herein provided and for the equal, ratable and common benefit of all holders of Securities of such series. For the protection and enforcement of the provisions of this Section, each and every Securityholder and the Trustee shall
be entitled to such relief as can be given either at law or in equity. 
  

	 	Section 6.05	Rights and Remedies Cumulative; Delay or Omission Not Waiver. 

 (a) Except as otherwise provided in Section 2.07, all powers and remedies given by this Article to the Trustee or to the Securityholders shall, to the extent permitted by law, be deemed
cumulative and not exclusive of any other powers and remedies available to the Trustee or the holders of the Securities, by judicial proceedings or otherwise, to enforce the performance or observance of the covenants and agreements contained in this
Indenture or otherwise established with respect to such Securities. 
 (b) No delay or omission of the Trustee or of any
holder of any of the Securities to exercise any right or power accruing upon any Event of Default occurring and continuing as aforesaid shall impair any such right or power, or shall be construed to be a waiver of any such default or an acquiescence
therein; and, subject to the provisions of Section 6.04, every power and remedy given by this Article or by law to the Trustee or the Securityholders may be exercised from time to time, and as often as shall be deemed expedient, by the Trustee
or by the Securityholders. 

  
 28.

	 	Section 6.06	Control by Securityholders. 

 The holders of a majority in aggregate principal amount of the Securities of any series at the time Outstanding, determined in accordance with Section 8.04, shall have the right to direct the time,
method and place of conducting any proceeding for any remedy available to the Trustee, or exercising any trust or power conferred on the Trustee with respect to such series; provided, however, that such direction shall not be in conflict with any
rule of law or with this Indenture or subject the Trustee in its sole discretion to personal liability. Subject to the provisions of Section 7.01, the Trustee shall have the right to decline to follow any such direction if the Trustee in good
faith shall, by a Responsible Officer or officers of the Trustee, determine that the proceeding so directed, subject to the Trustee’s duties under the Trust Indenture Act, would involve the Trustee in personal liability or might be unduly
prejudicial to the Securityholders not involved in the proceeding. The holders of a majority in aggregate principal amount of the Securities of any series at the time Outstanding affected thereby, determined in accordance with Section 8.04, may
on behalf of the holders of all of the Securities of such series waive any past default in the performance of any of the covenants contained herein or established pursuant to Section 2.01 with respect to such series and its consequences, except
a default in the payment of the principal of, or premium, if any, or interest on, any of the Securities of that series as and when the same shall become due by the terms of such Securities otherwise than by acceleration (unless such default has been
cured and a sum sufficient to pay all matured installments of interest and principal and any premium has been deposited with the Trustee (in accordance with Section 6.01(c)). Upon any such waiver, the default covered thereby shall be deemed to
be cured for all purposes of this Indenture and the Company, the Trustee and the holders of the Securities of such series shall be restored to their former positions and rights hereunder, respectively; but no such waiver shall extend to any
subsequent or other default or impair any right consequent thereon. 
  

	 	Section 6.07	Undertaking to Pay Costs. 

All parties to this Indenture agree, and each holder of any Securities by such holder’s acceptance thereof shall be deemed to have
agreed, that any court may in its discretion require, in any suit for the enforcement of any right or remedy under this Indenture, or in any suit against the Trustee for any action taken or omitted by it as Trustee, the filing by any party litigant
in such suit of an undertaking to pay the costs of such suit, and that such court may in its discretion assess reasonable costs, including reasonable attorneys’ fees and expenses, against any party litigant in such suit, having due regard to
the merits and good faith of the claims or defenses made by such party litigant; but the provisions of this Section shall not apply to any suit instituted by the Trustee, to any suit instituted by any Securityholder, or group of Securityholders,
holding more than 10% in aggregate principal amount of the Outstanding Securities of any series, or to any suit instituted by any Securityholder for the enforcement of the payment of the principal of (or premium, if any) or interest on any Security
of such series, on or after the respective due dates expressed in such Security or established pursuant to this Indenture. 

  
 29.

 ARTICLE 7 
 CONCERNING THE TRUSTEE 
  

	 	Section 7.01	Certain Duties and Responsibilities of Trustee. 

 (a) The Trustee, prior to the occurrence of an Event of Default with respect to the Securities of a series and after the curing of all Events of Default with respect to the Securities of that
series that may have occurred, shall undertake to perform with respect to the Securities of such series such duties and only such duties as are specifically set forth in this Indenture, and no implied covenants shall be read into this Indenture
against the Trustee. In case an Event of Default with respect to the Securities of a series has occurred (that has not been cured or waived), the Trustee shall exercise with respect to Securities of that series such of the rights and powers vested
in it by this Indenture, and use the same degree of care and skill in their exercise, as a prudent person would exercise or use under the circumstances in the conduct of his or her own affairs. 

(b) No provision of this Indenture shall be construed to relieve the Trustee from liability for its own negligent action, its own
negligent failure to act, or its own willful misconduct, except that: 
 (i) prior to the occurrence of an Event of
Default with respect to the Securities of a series and after the curing or waiving of all such Events of Default with respect to that series that may have occurred: 
 (A) the duties and obligations of the Trustee shall with respect to the Securities of such series be determined solely by the express provisions of this Indenture, and the Trustee shall not be
liable with respect to the Securities of such series except for the performance of such duties and obligations as are specifically set forth in this Indenture, and no implied covenants or obligations shall be read into this Indenture against the
Trustee; and 
 (B) in the absence of bad faith on the part of the Trustee, the Trustee may with respect to the
Securities of such series conclusively rely, as to the truth of the statements and the correctness of the opinions expressed therein, upon any certificates or opinions furnished to the Trustee and conforming to the requirements of this Indenture;
but in the case of any such certificates or opinions that by any provision hereof are specifically required to be furnished to the Trustee, the Trustee shall be under a duty to examine the same to determine whether or not they conform to the
requirements of this Indenture (but need not confirm or investigate the accuracy of mathematical calculations or other facts stated therein); 
 (ii) the Trustee shall not be liable for any error of judgment made in good faith by a Responsible Officer or Responsible Officers of the Trustee, unless it shall be proved that the Trustee was
negligent in ascertaining the pertinent facts; 

  
 30.

 (iii) the Trustee shall not be liable with respect to any action taken or omitted to
be taken by it in good faith in accordance with the direction of the holders of not less than a majority in principal amount of the Securities of any series at the time Outstanding relating to the time, method and place of conducting any proceeding
for any remedy available to the Trustee, or exercising any trust or power conferred upon the Trustee under this Indenture with respect to the Securities of that series; and 
 (iv) none of the provisions contained in this Indenture shall require the Trustee to expend or risk its own funds or otherwise incur personal financial liability in the performance of any of its
duties or in the exercise of any of its rights or powers if there is reasonable ground for believing that the repayment of such funds or liability is not reasonably assured to it under the terms of this Indenture or adequate indemnity against such
risk is not reasonably assured to it. 
  

	 	Section 7.02	Certain Rights of Trustee. 

Except as otherwise provided in Section 7.01: 
 (a) The Trustee may conclusively rely and shall be protected in acting or refraining from acting upon any resolution, certificate, statement, instrument, opinion, report, notice, request, consent,
order, approval, bond, security or other paper or document believed by it to be genuine and to have been signed or presented by the proper party or parties; 
 (b) Any request, direction, order or demand of the Company mentioned herein shall be sufficiently evidenced by a Board Resolution or an instrument signed in the name of the Company by any
authorized officer of the Company (unless other evidence in respect thereof is specifically prescribed herein); 
 (c)
The Trustee may consult with counsel of its selection and the advice of such counsel or any Opinion of Counsel shall be full and complete authorization and protection in respect of any action taken or suffered or omitted hereunder in good faith
and in reliance thereon; 
 (d) The Trustee shall be under no obligation to exercise any of the rights or powers vested
in it by this Indenture at the request, order or direction of any of the Securityholders pursuant to the provisions of this Indenture, unless such Securityholders shall have offered to the Trustee security or indemnity satisfactory to it against the
costs, expenses and liabilities that may be incurred therein or thereby; nothing contained herein shall, however, relieve the Trustee of the obligation, upon the occurrence of an Event of Default with respect to a series of the Securities (that has
not been cured or waived), to exercise with respect to Securities of that series such of the rights and powers vested in it by this Indenture, and to use the same degree of care and skill in their exercise, as a prudent person would exercise or use
under the circumstances in the conduct of his or her own affairs; 

  
 31.

 (e) The Trustee shall not be liable for any action taken or omitted to be taken by it
in good faith and believed by it to be authorized or within the discretion or rights or powers conferred upon it by this Indenture; 
 (f) The Trustee shall not be bound to make any investigation into the facts or matters stated in any resolution, certificate, statement, instrument, opinion, report, notice, request, consent,
order, approval, bond, security, or other papers or documents, unless requested in writing so to do by the holders of not less than a majority in principal amount of the Outstanding Securities of the particular series affected thereby (determined as
provided in Section 8.04); provided, however, that if the payment within a reasonable time to the Trustee of the costs, expenses or liabilities likely to be incurred by it in the making of such investigation is, in the opinion of the Trustee,
not reasonably assured to the Trustee by the security afforded to it by the terms of this Indenture, the Trustee may require security and indemnity satisfactory to it against such costs, expenses or liabilities as a condition to so proceeding. The
reasonable expense of every such examination shall be paid by the Company or, if paid by the Trustee, shall be repaid by the Company upon demand; 
 (g) The Trustee may execute any of the trusts or powers hereunder or perform any duties hereunder either directly or by or through agents or attorneys and the Trustee shall not be responsible for
any misconduct or negligence on the part of any agent or attorney appointed with due care by it hereunder; 
 (h) In no
event shall the Trustee be responsible or liable for any failure or delay in the performance of its obligations hereunder arising out of or caused by, directly or indirectly, forces beyond its control, including, without limitation, strikes, work
stoppages, accidents, acts of war or terrorism, civil or military disturbances, nuclear or natural catastrophes or acts of God, and interruptions, loss or malfunctions of utilities, communications or computer (software and hardware) services; it
being understood that the Trustee shall use reasonable efforts which are consistent with accepted practices in the banking industry to resume performance as soon as practicable under the circumstances; 

(i) In no event shall the Trustee be responsible or liable for special, indirect, punitive or consequential loss or damage of any
kind whatsoever (including, but not limited to, loss of profit) irrespective of whether the Trustee has been advised of the likelihood of such loss or damage and regardless of the form of action; 

(j) The rights, privileges, protections, immunities and benefits given to the Trustee, including, without limitation, its right to
be indemnified, are extended to, and shall be enforceable by, the Trustee in each of its capacities hereunder, and each agent, custodian and other Person employed to act hereunder; and 

(k) The Trustee shall not be required to give any bond or surety in respect of the performance of its powers and duties hereunder
agrees to accept and act upon instructions or directions pursuant to this Indenture sent by facsimile transmission; provided, however, that (a) the party providing such written instructions, subsequent to such transmission of written

  
 32.

 
instructions, shall provide the originally executed instructions or directions to the Trustee in a timely manner, and (b) such originally executed instructions or directions shall be signed
by an authorized representative of the party providing such instructions or directions. If the party elects to give the Trustee facsimile instructions and the Trustee in its sole discretion elects to act upon such instructions, the Trustee’s
understanding of such instructions shall be deemed controlling. The Trustee shall not be liable for any losses, costs or expenses arising directly or indirectly from the Trustee’s reliance upon and compliance with such instructions
notwithstanding such instructions conflict or are inconsistent with a subsequent written instruction. The party providing electronic instructions agrees to assume all risks arising out of the use of such electronic methods to submit instructions and
directions to the Trustee, including without limitation the risk of the Trustee acting on unauthorized instructions, and the risk or interception and misuse by third parties. 
 (l) Before the Trustee acts or refrains from acting, it may require an Officers’ Certificate and an Opinion of Counsel. The Trustee shall not be liable for any action it takes or omits to take
in good faith in reliance on such certificate or opinion. 
 In addition, the Trustee shall not be deemed to have knowledge of
an Event of Default other than an Event of Default relating to the failure to pay the interest on, or the principal of, the Securities, until the Trustee shall have received written notification in the manner set forth in this Indenture or a
Responsible Officer of the Trustee shall have obtained actual knowledge. 
  

	 	Section 7.03	Trustee Not Responsible for Recitals or Issuance or Securities. 

 (a) The recitals contained herein and in the Securities shall be taken as the statements of the Company, and the Trustee assumes no responsibility for the correctness of the same. 

(b) The Trustee makes no representations as to the validity or sufficiency of this Indenture or of the Securities. 

(c) The Trustee shall not be accountable for the use or application by the Company of any of the Securities or of the proceeds of
such Securities, or for the use or application of any moneys paid over by the Trustee in accordance with any provision of this Indenture or established pursuant to Section 2.01, or for the use or application of any moneys received by any paying
agent other than the Trustee. 
  

	 	Section 7.04	May Hold Securities. 

 The
Trustee or any paying agent or Security Registrar, in its individual or any other capacity, may become the owner or pledgee of Securities with the same rights it would have if it were not Trustee, paying agent or Security Registrar. 

  
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	 	Section 7.05	Moneys Held in Trust. 

Subject to the provisions of Section 11.05, all moneys received by the Trustee shall, until used or applied as herein provided, be
held in trust for the purposes for which they were received, but need not be segregated from other funds except to the extent required by law. The Trustee shall be under no liability for interest on any moneys received by it hereunder except such as
it may agree to in writing with the Company to pay thereon. 
  

	 	Section 7.06	Compensation and Reimbursement. 

 (a) The Company covenants and agrees to pay to the Trustee, and the Trustee shall be entitled to, such compensation (which shall not be limited by any provision of law in regard to the compensation
of a trustee of an express trust) as the Company and the Trustee may from time to time agree in writing, for all services rendered by it in the execution of the trusts hereby created and in the exercise and performance of any of the powers and
duties hereunder of the Trustee, and, except as otherwise expressly provided herein, the Company will pay or reimburse the Trustee upon its request for all reasonable expenses, disbursements and advances incurred or made by the Trustee in accordance
with any of the provisions of this Indenture (including the reasonable compensation and the expenses and disbursements of its counsel and of all Persons not regularly in its employ), except any such expense, disbursement or advance as may arise from
its negligence or bad faith and except as the Company and Trustee may from time to time agree in writing. The Company also covenants to indemnify the Trustee (and its officers, agents, directors and employees) for, and to hold it harmless against,
any and all loss, liability, damage, claim or expense incurred without negligence or willful misconduct on the part of the Trustee and arising out of or in connection with the acceptance or administration of this trust, including the reasonable
costs and expenses of defending itself against any claim (whether asserted by the Company, a Securityholder or any other person) of liability in the premises. 
 (b) The obligations of the Company under this Section to compensate and indemnify the Trustee and to pay or reimburse the Trustee for reasonable expenses, disbursements and advances shall
constitute additional indebtedness hereunder. Such additional indebtedness shall be secured by a lien prior to that of the Securities upon all property and funds held or collected by the Trustee as such, except funds held in trust for the benefit of
the holders of particular Securities. 
 (c) To ensure the Company’s payment obligations in this Section, the
Trustee shall have a lien prior to the Securities on all funds or property held or collected by the Trustee, except that held in trust to pay principal of or interest on particular Securities. When the Trustee incurs expenses or renders services in
connection with an Event of Default specified in Section 6.01(4) or (5), the expenses (including the reasonable fees and expenses of its counsel) and the compensation for services in connection therewith are to constitute expenses of
administration under any bankruptcy law. The provisions of this Section 7.06 shall survive the termination of this Indenture and the resignation or removal of the Trustee. 

  
 34.

	 	Section 7.07	Reliance on Officer’s Certificate. 

 Except as otherwise provided in Section 7.01, whenever in the administration of the provisions of this Indenture the Trustee shall deem it reasonably necessary or desirable that a matter be proved or
established prior to taking or suffering or omitting to take any action hereunder, such matter (unless other evidence in respect thereof be herein specifically prescribed) may, in the absence of negligence or willful misconduct on the part of the
Trustee, be deemed to be conclusively proved and established by an Officer’s Certificate delivered to the Trustee and such certificate, in the absence of negligence or willful misconduct on the part of the Trustee, shall be full warrant to the
Trustee for any action taken, suffered or omitted to be taken by it under the provisions of this Indenture upon the faith thereof. 
  

	 	Section 7.08	Disqualification; Conflicting Interests. 

 If the Trustee has or shall acquire any “conflicting interest” within the meaning of Section 310(b) of the Trust Indenture Act, the Trustee and the Company shall in all respects comply with
the provisions of Section 310(b) of the Trust Indenture Act. 
  

	 	Section 7.09	Corporate Trustee Required; Eligibility. 

 There shall at all times be a Trustee with respect to the Securities issued hereunder which shall at all times be a corporation organized and doing business under the laws of the United States of America
or any state or territory thereof or of the District of Columbia, or a corporation or other Person permitted to act as trustee by the Commission, authorized under such laws to exercise corporate trust powers, having a combined capital and surplus of
at least fifty million U.S. dollars ($50,000,000), and subject to supervision or examination by federal, state, territorial, or District of Columbia authority. 
 If such corporation or other Person publishes reports of condition at least annually, pursuant to law or to the requirements of the aforesaid supervising or examining authority, then for the purposes of
this Section, the combined capital and surplus of such corporation or other Person shall be deemed to be its combined capital and surplus as set forth in its most recent report of condition so published. The Company may not, nor may any Person
directly or indirectly controlling, controlled by, or under common control with the Company, serve as Trustee. In case at any time the Trustee shall cease to be eligible in accordance with the provisions of this Section, the Trustee shall resign
immediately in the manner and with the effect specified in Section 7.10. 
  

	 	Section 7.10	Resignation and Removal; Appointment of Successor. 

 (a) The Trustee or any successor hereafter appointed may at any time resign with respect to the Securities of one or more series by giving written notice thereof to the Company and by transmitting
notice of resignation by mail, first class postage prepaid, to the Securityholders of such series, as their names and addresses appear upon the Security Register. Upon receiving such notice of resignation, the Company shall promptly appoint a
successor 

  
 35.

 
trustee with respect to Securities of such series by written instrument, in duplicate, executed by order of the Board of Directors, one copy of which instrument shall be delivered to the
resigning Trustee and one copy to the successor trustee. If no successor trustee shall have been so appointed and have accepted appointment within 30 days after the mailing of such notice of resignation, the resigning Trustee may petition, at the
expense of the Company, any court of competent jurisdiction for the appointment of a successor trustee with respect to Securities of such series, or any Securityholder of that series who has been a bona fide holder of a Security or Securities for at
least six months may on behalf of himself and all others similarly situated, petition any such court for the appointment of a successor trustee. Such court may thereupon after such notice, if any, as it may deem proper and prescribe, appoint a
successor trustee. 
 (b) In case at any time any one of the following shall occur: 

(i) the Trustee shall fail to comply with the provisions of Section 7.08 after written request therefor by the Company or by
any Securityholder who has been a bona fide holder of a Security or Securities for at least six months; or 
 (ii) the
Trustee shall cease to be eligible in accordance with the provisions of Section 7.09 and shall fail to resign after written request therefor by the Company or by any such Securityholder; or 

(iii) the Trustee shall become incapable of acting, or shall be adjudged a bankrupt or insolvent, or commence a voluntary
bankruptcy proceeding, or a receiver of the Trustee or of its property shall be appointed or consented to, or any public officer shall take charge or control of the Trustee or of its property or affairs for the purpose of rehabilitation,
conservation or liquidation; 
 then, in any such case, the Company may remove the Trustee with respect to all Securities and
appoint a successor trustee by written instrument, in duplicate, executed by order of the Board of Directors, one copy of which instrument shall be delivered to the Trustee so removed and one copy to the successor trustee, or any Securityholder who
has been a bona fide holder of a Security or Securities for at least six months may, on behalf of that holder and all others similarly situated, petition any court of competent jurisdiction for the removal of the Trustee and the appointment of a
successor trustee. Such court may thereupon after such notice, if any, as it may deem proper and prescribe, remove the Trustee and appoint a successor trustee. 
 (c) The holders of a majority in aggregate principal amount of the Securities of any series at the time Outstanding may at any time remove the Trustee with respect to such series by so notifying
the Trustee and the Company and may appoint a successor Trustee for such series with the consent of the Company. If no successor trustee shall have been so appointed and have accepted appointment within 30 days after the mailing of such notice of
resignation, the resigning Trustee may petition, at the expense of the Company, any court of competent jurisdiction for the appointment of a successor trustee with respect to Securities of such series, or any Securityholder of that series who has
been a bona fide holder of a Security or Securities for at least six months may on behalf of himself and all others similarly situated, 

  
 36.

 
petition any such court for the appointment of a successor trustee. Such court may thereupon after such notice, if any as it may deem proper and prescribe, appoint a successor trustee.

 (d) Any resignation or removal of the Trustee and appointment of a successor trustee with respect to the Securities of
a series pursuant to any of the provisions of this Section shall become effective upon acceptance of appointment by the successor trustee as provided in Section 7.11. 

 

	 	Section 7.11	Acceptance of Appointment By Successor. 

 (a) In case of the appointment hereunder of a successor trustee with respect to all Securities, every such successor trustee so appointed shall execute, acknowledge and deliver to the Company and
to the retiring Trustee an instrument accepting such appointment, and thereupon the resignation or removal of the retiring Trustee shall become effective and such successor trustee, without any further act, deed or conveyance, shall become vested
with all the rights, powers, trusts and duties of the retiring Trustee; but, on the request of the Company or the successor trustee, such retiring Trustee shall, upon payment of its charges, execute and deliver an instrument transferring to such
successor trustee all the rights, powers, and trusts of the retiring Trustee and shall duly assign, transfer and deliver to such successor trustee all property and money held by such retiring Trustee hereunder. 

(b) In case of the appointment hereunder of a successor trustee with respect to the Securities of one or more (but not all)
series, the Company, the retiring Trustee and each successor trustee with respect to the Securities of one or more series shall execute and deliver an indenture supplemental hereto wherein each successor trustee shall accept such appointment and
which (i) shall contain such provisions as shall be necessary or desirable to transfer and confirm to, and to vest in, each successor trustee all the rights, powers, trusts and duties of the retiring Trustee with respect to the Securities of
that or those series to which the appointment of such successor trustee relates, (ii) shall contain such provisions as shall be deemed necessary or desirable to confirm that all the rights, powers, trusts and duties of the retiring Trustee with
respect to the Securities of that or those series as to which the retiring Trustee is not retiring shall continue to be vested in the retiring Trustee, and (iii) shall add to or change any of the provisions of this Indenture as shall be
necessary to provide for or facilitate the administration of the trusts hereunder by more than one Trustee, it being understood that nothing herein or in such supplemental indenture shall constitute such Trustees co-trustees of the same trust, that
each such Trustee shall be trustee of a trust or trusts hereunder separate and apart from any trust or trusts hereunder administered by any other such Trustee and that no Trustee shall be responsible for any act or failure to act on the part of any
other Trustee hereunder; and upon the execution and delivery of such supplemental indenture the resignation or removal of the retiring Trustee shall become effective to the extent provided therein, such retiring Trustee shall with respect to the
Securities of that or those series to which the appointment of such successor trustee relates have no further responsibility for the exercise of rights and powers or for the performance of the duties and obligations vested in the Trustee under this
Indenture, and each such successor trustee, without any further act, deed or conveyance, shall become vested with all the rights, 

  
 37.

 
powers, trusts and duties of the retiring Trustee with respect to the Securities of that or those series to which the appointment of such successor trustee relates; but, on request of the Company
or any successor trustee, such retiring Trustee shall duly assign, transfer and deliver to such successor trustee, to the extent contemplated by such supplemental indenture, the property and money held by such retiring Trustee hereunder with respect
to the Securities of that or those series to which the appointment of such successor trustee relates. 
 (c) Upon request
of any such successor trustee, the Company shall execute any and all instruments for more fully and certainly vesting in and confirming to such successor trustee all such rights, powers and trusts referred to in paragraph (a) or (b) of
this Section, as the case may be. 
 (d) No successor trustee shall accept its appointment unless at the time of such
acceptance such successor trustee shall be qualified and eligible under this Article. 
 (e) Upon acceptance of
appointment by a successor trustee as provided in this Section, the Company shall transmit notice of the succession of such trustee hereunder by mail, first class postage prepaid, to the Securityholders, as their names and addresses appear upon the
Security Register. If the Company fails to transmit such notice within ten days after acceptance of appointment by the successor trustee, the successor trustee shall cause such notice to be transmitted at the expense of the Company. 

 

	 	Section 7.12	Merger, Conversion, Consolidation or Succession to Business. 

 Any corporation into which the Trustee may be merged or converted or with which it may be consolidated, or any corporation resulting from any merger, conversion or consolidation to which the Trustee shall
be a party, or any corporation succeeding to the corporate trust business of the Trustee, including the administration of the trust created by this Indenture, shall be the successor of the Trustee hereunder, provided that such corporation shall be
qualified under the provisions of Section 7.08 and eligible under the provisions of Section 7.09, without the execution or filing of any paper or any further act on the part of any of the parties hereto, anything herein to the contrary
notwithstanding. In case any Securities shall have been authenticated, but not delivered, by the Trustee then in office, any successor by merger, conversion or consolidation to such authenticating Trustee may adopt such authentication and deliver
the Securities so authenticated with the same effect as if such successor Trustee had itself authenticated such Securities. 
  

	 	Section 7.13	Preferential Collection of Claims Against the Company. 

 The Trustee shall comply with Section 311(a) of the Trust Indenture Act, excluding any creditor relationship described in Section 311(b) of the Trust Indenture Act. A Trustee who has resigned or
been removed shall be subject to Section 311(a) of the Trust Indenture Act to the extent included therein. 
  

	 	Section 7.14	Notice of Default 

  
 38.

 If any Event of Default occurs and is continuing and if such Event of Default is actually
known to a Responsible Officer of the Trustee, the Trustee shall mail to each Securityholder in the manner and to the extent provided in Section 313(c) of the Trust Indenture Act notice of the Event of Default within 90 days after it occurs or,
if later, after it is known to a Responsible Officer of the Trustee or written notice of it is received by the Trustee, unless such Event of Default has been cured; provided, however, that, except in the case of a default in the payment of
the principal of (or premium, if any) or interest on any Security, the Trustee shall be protected in withholding such notice if and so long as the board of directors, the executive committee or a trust committee of directors and/or Responsible
Officers of the Trustee in good faith determine that the withholding of such notice is in the interest of the Securityholders. 

ARTICLE 8 

CONCERNING THE SECURITYHOLDERS 
  

	 	Section 8.01	Evidence of Action by Securityholders. 

 Whenever in this Indenture it is provided that the holders of a majority or specified percentage in aggregate principal amount of the Securities of a particular series may take any action (including the
making of any demand or request, the giving of any notice, consent or waiver or the taking of any other action), the fact that at the time of taking any such action the holders of such majority or specified percentage of that series have joined
therein may be evidenced by any instrument or any number of instruments of similar tenor executed by such holders of Securities of that series in person or by agent or proxy appointed in writing. 

If the Company shall solicit from the Securityholders of any series any request, demand, authorization, direction, notice, consent,
waiver or other action, the Company may, at its option, as evidenced by an Officer’s Certificate, fix in advance a record date for such series for the determination of Securityholders entitled to give such request, demand, authorization,
direction, notice, consent, waiver or other action, but the Company shall have no obligation to do so. If such a record date is fixed, such request, demand, authorization, direction, notice, consent, waiver or other action may be given before or
after the record date, but only the Securityholders of record at the close of business on the record date shall be deemed to be Securityholders for the purposes of determining whether Securityholders of the requisite proportion of Outstanding
Securities of that series have authorized or agreed or consented to such request, demand, authorization, direction, notice, consent, waiver or other action, and for that purpose the Outstanding Securities of that series shall be computed as of the
record date; provided, however, that no such authorization, agreement or consent by such Securityholders on the record date shall be deemed effective unless it shall become effective pursuant to the provisions of this Indenture not later than six
months after the record date. 
  

	 	Section 8.02	Proof of Execution by Securityholders. 

 Subject to the provisions of Section 7.01, proof of the execution of any instrument by a Securityholder (such proof will not require notarization) or his agent or proxy and proof of the

  
 39.

 
holding by any Person of any of the Securities shall be sufficient if made in the following manner: 
 (a) The fact and date of the execution by any such Person of any instrument may be proved in any reasonable manner acceptable to the Trustee. 

(b) The ownership of Securities shall be proved by the Security Register of such Securities or by a certificate of the Security
Registrar thereof. 
 The Trustee may require such additional proof of any matter referred to in this Section as it shall deem necessary.

  

	 	Section 8.03	Who May be Deemed Owners. 

Prior to the due presentment for registration of transfer of any Security, the Company, the Trustee, any paying agent and any Security
Registrar may deem and treat the Person in whose name such Security shall be registered upon the books of the Security Registrar as the absolute owner of such Security (whether or not such Security shall be overdue and notwithstanding any notice of
ownership or writing thereon made by anyone other than the Security Registrar) for the purpose of receiving payment of or on account of the principal of, premium, if any, and (subject to Section 2.03) interest on such Security and for all other
purposes; and neither the Company nor the Trustee nor any paying agent nor any Security Registrar shall be affected by any notice to the contrary. 
  

	 	Section 8.04	Certain Securities Owned by Company Disregarded. 

 In determining whether the holders of the requisite aggregate principal amount of Securities of a particular series have concurred in any direction, consent or waiver under this Indenture, the Securities
of that series that are owned by the Company or any other obligor on the Securities of that series or by any Person directly or indirectly controlling or controlled by or under common control with the Company or any other obligor on the Securities
of that series shall be disregarded and deemed not to be Outstanding for the purpose of any such determination, except that for the purpose of determining whether the Trustee shall be protected in relying on any such direction, consent or waiver,
only Securities of such series that a Responsible Officer of the Trustee actually knows are so owned shall be so disregarded. The Securities so owned that have been pledged in good faith may be regarded as Outstanding for the purposes of this
Section, if the pledgee shall establish to the satisfaction of the Trustee the pledgee’s right so to act with respect to such Securities and that the pledgee is not a Person directly or indirectly controlling or controlled by or under direct or
indirect common control with the Company or any such other obligor. In case of a dispute as to such right, any decision by the Trustee taken upon the advice of counsel shall be full protection to the Trustee. 

  
 40.

	 	Section 8.05	Actions Binding on Future Securityholders. 

 At any time prior to (but not after) the evidencing to the Trustee, as provided in Section 8.01, of the taking of any action by the holders of the majority or percentage in aggregate principal amount
of the Securities of a particular series specified in this Indenture in connection with such action, any holder of a Security of that series that is shown by the evidence to be included in the Securities the holders of which have consented to such
action may, by filing written notice with the Trustee, and upon proof of holding as provided in Section 8.02, revoke such action so far as concerns such Security. Except as aforesaid any such action taken by the holder of any Security shall be
conclusive and binding upon such holder and upon all future holders and owners of such Security, and of any Security issued in exchange therefor, on registration of transfer thereof or in place thereof, irrespective of whether or not any notation in
regard thereto is made upon such Security. Any action taken by the holders of the majority or percentage in aggregate principal amount of the Securities of a particular series specified in this Indenture in connection with such action shall be
conclusively binding upon the Company, the Trustee and the holders of all the Securities of that series. 
 ARTICLE 9

 SUPPLEMENTAL INDENTURES 
  

	 	Section 9.01	Supplemental Indentures Without the Consent of Securityholders. 

 In addition to any supplemental indenture otherwise authorized by this Indenture, the Company and the Trustee may from time to time and at any time enter into an indenture or indentures supplemental
hereto (which shall conform to the provisions of the Trust Indenture Act as then in effect), without the consent of any Securityholders, for one or more of the following purposes: 

(a) to cure any ambiguity, defect, or inconsistency in this Indenture or in the Securities of any series; 

(b) to comply with Article Ten; 
 (c) to provide for uncertificated Securities in addition to or in place of certificated Securities; 
 (d) to add to the covenants, restrictions, conditions or provisions such new covenants, restrictions, conditions or provisions for the benefit of the Securityholders, to make the occurrence, or the
occurrence and the continuance, of a default in any such additional covenants, restrictions, conditions or provisions an Event of Default, or to surrender any right or power conferred upon the Company in this Indenture; 

  
 41.

 (e) to add to, delete from, or revise the conditions, limitations, and restrictions
on the authorized amount, terms, or purposes of issue, authentication, and delivery of Securities, as set forth in this Indenture; 
 (f) to make any change that does not adversely affect the rights of any Securityholder in any material respect; 
 (g) to provide for the issuance of and establish the form and terms and conditions of the Securities of any series as provided in Section 2.01, to establish the form of any certifications
required to be furnished pursuant to the terms of this Indenture or any series of Securities, or to add to the rights of the holders of any series of Securities; 
 (h) to evidence and provide for the acceptance of appointment under this Indenture by a successor trustee; or 
 (i) to comply with any requirements of the Commission with the qualification of this Indenture under the Trust Indenture Act. 

The Trustee is hereby authorized to join with the Company in the execution of any such supplemental indenture, and to make any further
appropriate agreements and stipulations that may be therein contained, but the Trustee shall not be obligated to enter into any such supplemental indenture that affects the Trustee’s own rights, duties or immunities under this Indenture or
otherwise. 
 Any supplemental indenture authorized by the provisions of this Section may be executed by the Company and the
Trustee without the consent of the holders of any of the Securities at the time Outstanding, notwithstanding any of the provisions of Section 9.02. 
  

	 	Section 9.02	Supplemental Indentures With Consent of Securityholders. 

 With the written consent of the holders of at least a majority in aggregate principal amount of the Securities of each series affected by such supplemental indenture or indentures at the time Outstanding,
the Company, when authorized by a Board Resolution, and the Trustee may from time to time and at any time enter into an indenture or indentures supplemental hereto (which shall conform to the provisions of the Trust Indenture Act as then in effect)
for the purpose of adding any provisions to or changing in any manner or eliminating any of the provisions of this Indenture or of any supplemental indenture or of modifying in any manner not covered by Section 9.01 the rights of the holders of
the Securities of such series under this Indenture; provided, however, that no such supplemental indenture shall, without the consent of the holders of each Security then Outstanding and affected thereby, (a) extend the fixed maturity of any
Securities of any series, (b) reduce the principal amount, reduce the rate of or extend the time of payment of interest, or reduce any premium payable upon the redemption of any series of Securities or (b) reduce the percentage of
Securities, the holders of which are required to consent to any amendment, supplement, modification or waiver. 

  
 42.

 It shall not be necessary for the consent of the Securityholders of any series affected
thereby under this Section to approve the particular form of any proposed supplemental indenture, but it shall be sufficient if such consent shall approve the substance thereof. 

 

	 	Section 9.03	Effect of Supplemental Indentures. 

 Upon the execution of any supplemental indenture pursuant to the provisions of this Article or of Section 10.01, this Indenture shall, with respect to such series, be and be deemed to be modified and
amended in accordance therewith and the respective rights, limitations of rights, obligations, duties and immunities under this Indenture of the Trustee, the Company and the holders of Securities of the series affected thereby shall thereafter be
determined, exercised and enforced hereunder subject in all respects to such modifications and amendments, and all the terms and conditions of any such supplemental indenture shall be and be deemed to be part of the terms and conditions of this
Indenture for any and all purposes. 
  

	 	Section 9.04	Securities Affected by Supplemental Indentures. 

 Securities of any series affected by a supplemental indenture, authenticated and delivered after the execution of such supplemental indenture pursuant to the provisions of this Article or of
Section 10.01, may bear a notation in form approved by the Company, provided such form meets the requirements of any securities exchange upon which such series may be listed, as to any matter provided for in such supplemental indenture. If the
Company shall so determine, new Securities of that series so modified as to conform, in the opinion of the Board of Directors, to any modification of this Indenture contained in any such supplemental indenture may be prepared by the Company,
authenticated by the Trustee and delivered in exchange for the Securities of that series then Outstanding. 
  

	 	Section 9.05	Execution of Supplemental Indentures. 

 Upon the request of the Company, accompanied by its Board Resolutions authorizing the execution of any such supplemental indenture, and upon the filing with the Trustee of evidence of the consent of
Securityholders required to consent thereto as aforesaid, the Trustee shall join with the Company in the execution of such supplemental indenture unless such supplemental indenture affects the Trustee’s own rights, duties or immunities under
this Indenture or otherwise, in which case the Trustee may in its discretion but shall not be obligated to enter into such supplemental indenture. The Trustee, subject to the provisions of Sections 7.01 and 7.02, shall receive an Officer’s
Certificate upon request and an Opinion of Counsel as conclusive evidence that any supplemental indenture executed pursuant to this Article is authorized or permitted by the terms of this Article, that all conditions precedent to the execution of
the supplemental indenture have been complied with and the Supplemental Indenture is a valid and legally binding instrument enforceable against the Company. 
 Promptly after the execution by the Company and the Trustee of any supplemental indenture pursuant to the provisions of this Section, the Company shall (or shall direct the Trustee to) transmit, at the
expense of the Company, by mail, first class postage prepaid, a 

  
 43.

 
notice, setting forth in general terms the substance of such supplemental indenture, to the Securityholders of all series affected thereby .as their names and addresses appear upon the Security
Register. Any failure of the Company to mail, or cause the mailing of, such notice, or any defect therein, shall not, however, in any way impair or affect the validity of any such supplemental indenture. 

ARTICLE 10 

SUCCESSOR ENTITY 
  

	 	Section 10.01	Company May Consolidate, Etc. 

 Nothing contained in this Indenture shall prevent any consolidation or merger of the Company with or into any other Person (whether or not affiliated with the Company) or successive consolidations or
mergers in which the Company or its successor or successors shall be a party or parties, or shall prevent any sale, conveyance, transfer or other disposition of the property of the Company or its successor or successors as an entirety, or
substantially as an entirety, to any other corporation (whether or not affiliated with the Company or its successor or successors) authorized to acquire and operate the same; provided, however, the Company hereby covenants and agrees that, upon any
such consolidation or merger (in each case, if the Company is not the survivor of such transaction), sale, conveyance, transfer or other disposition, the due and punctual payment of the principal of (premium, if any) and interest on all of the
Securities of all series in accordance with the terms of each series, according to their tenor, and the due and punctual performance and observance of all the covenants and conditions of this Indenture with respect to each series or established with
respect to such series pursuant to Section 2.01 to be kept or performed by the Company shall be expressly assumed, by supplemental indenture (which shall conform to the provisions of the Trust Indenture Act, as then in effect) reasonably
satisfactory in form to the Trustee executed and delivered to the Trustee by the entity formed by such consolidation, or into which the Company shall have been merged, or by the entity which shall have acquired such property. 

 

	 	Section 10.02	Successor Entity Substituted. 

 (a) In case of any such consolidation, merger, sale, conveyance, transfer or other disposition and upon the assumption by the successor entity by supplemental indenture, executed and delivered to
the Trustee and satisfactory in form to the Trustee, of the obligations set forth under Section 10.01 on all of the Securities of all series Outstanding, such successor entity shall succeed to and be substituted for the Company with the same
effect as if it had been named as the Company herein, and thereupon the predecessor corporation shall be relieved of all obligations and covenants under this Indenture and the Securities. 

(b) In case of any such consolidation, merger, sale, conveyance, transfer or other disposition, such changes in phraseology and
form (but not in substance) may be made in the Securities thereafter to be issued as may be appropriate. 

  
 44.

 (c) Nothing contained in this Article shall require any action by the Company in the
case of a consolidation or merger of any Person into the Company where the Company is the survivor of such transaction, or the acquisition by the Company, by purchase or otherwise, of all or any part of the property of any other Person (whether or
not affiliated with the Company). 
  

	 	Section 10.03	Evidence of Consolidation, Etc. to Trustee. 

 The Trustee, subject to the provisions of Section 7.01, shall receive an Officer’s Certificate and an Opinion of Counsel as conclusive evidence that any such consolidation, merger, sale,
conveyance, transfer or other disposition, and any such assumption, comply with the provisions of this Article. 
 ARTICLE 11

 SATISFACTION AND DISCHARGE 
  

	 	Section 11.01	Satisfaction and Discharge of Indenture. 

 If at any time: (a) the Company shall have delivered to the Trustee for cancellation all Securities of a series theretofore authenticated and not delivered to the Trustee for cancellation (other than
any Securities that shall have been destroyed, lost or stolen and that shall have been replaced or paid as provided in Section 2.07 and Securities for whose payment money or Governmental Obligations have theretofore been deposited in trust or
segregated and held in trust by the Company and thereupon repaid to the Company or discharged from such trust, as provided in Section 11.05); or (b) all such Securities of a particular series not theretofore delivered to the Trustee for
cancellation shall have become due and payable, or are by their terms to become due and payable within one year or are to be called for redemption within one year under arrangements satisfactory to the Trustee for the giving of notice of redemption,
and the Company shall deposit or cause to be deposited with the Trustee as trust funds the entire amount in moneys or Governmental Obligations or a combination thereof, sufficient in the opinion of a nationally recognized firm of independent public
accountants expressed in a written certification thereof delivered to the Trustee, to pay at maturity or upon redemption all Securities of that series not theretofore delivered to the Trustee for cancellation, including principal (and premium, if
any) and interest due or to become due to such date of maturity or date fixed for redemption, as the case may be, and if the Company shall also pay or cause to be paid all other sums payable hereunder with respect to such series by the Company then
this Indenture shall thereupon cease to be of further effect with respect to such series except for the provisions of Sections 2.03, 2.05, 2.07, 4.01, 4.02, 4.03 and 7.10, that shall survive until the date of maturity or redemption date, as the case
may be, and Sections 7.06 and 11.05, that shall survive to such date and thereafter, and the Trustee, on demand of the Company and at the cost and expense of the Company shall execute proper instruments acknowledging satisfaction of and discharging
this Indenture with respect to such series. 

  
 45.

	 	Section 11.02	Discharge of Obligations. 

If at any time all such Securities of a particular series not heretofore delivered to the Trustee for cancellation or that have not become
due and payable as described in Section 11.01 shall have been paid by the Company by depositing irrevocably with the Trustee as trust funds moneys or an amount of Governmental Obligations sufficient to pay at maturity or upon redemption all
such Securities of that series not theretofore delivered to the Trustee for cancellation, including principal (and premium, if any) and interest due or to become due to such date of maturity or date fixed for redemption, as the case may be, and if
the Company shall also pay or cause to be paid all other sums payable hereunder by the Company with respect to such series, then after the date such moneys or Governmental Obligations, as the case may be, are deposited with the Trustee the
obligations of the Company under this Indenture with respect to such series shall cease to be of further effect except for the provisions of Sections 2.03, 2.05, 2.07, 4,01, 4.02, 4,03, 7.06, 7.10 and 11.05 hereof that shall survive until such
Securities shall mature and be paid. 
 Thereafter, Sections 7.06 and 11.05 shall survive. 

 

	 	Section 11.03	Deposited Moneys to be Held in Trust. 

 All moneys or Governmental Obligations deposited with the Trustee pursuant to Sections 11.01 or 11.02 shall be held in trust and shall be available for payment as due, either directly or through any
paying agent (including the Company acting as its own paying agent), to the holders of the particular series of Securities for the payment or redemption of which such moneys or Governmental Obligations have been deposited with the Trustee.

  

	 	Section 11.04	Payment of Moneys Held by Paying Agents. 

 In connection with the satisfaction and discharge of this Indenture all moneys or Governmental Obligations then held by any paying agent under the provisions of this Indenture shall, upon demand of the
Company, be paid to the Trustee and thereupon such paying agent shall be released from all further liability with respect to such moneys or Governmental Obligations. 
  

	 	Section 11.05	Repayment to Company. 

Any moneys or Governmental Obligations deposited with any paying agent or the Trustee, or then held by the Company, in trust for payment
of principal of or premium, if any, or interest on the Securities of a particular series that are not applied but remain unclaimed by the holders of such Securities for at least two years after the date upon which the principal of (and premium, if
any) or interest on such Securities shall have respectively become due and payable, or such other shorter period set forth in applicable escheat or abandoned or unclaimed property law, shall be repaid to the Company on May 31 of each year or
upon the Company’s request or (if then held by the Company) shall be discharged from such trust; and thereupon the paying agent and the Trustee shall be released from all further liability with respect to such moneys or

  
 46.

 
Governmental Obligations, and the holder of any of the Securities entitled to receive such payment shall thereafter, as a general creditor, look only to the Company for the payment thereof.

 ARTICLE 12 
 IMMUNITY OF INCORPORATORS, STOCKHOLDERS, OFFICERS AND DIRECTORS 
  

	 	Section 12.01	No Recourse. 

 No recourse
under or upon any obligation, covenant or agreement of this Indenture, or of any Security, or for any claim based thereon or otherwise in respect thereof, shall be had against any incorporator, stockholder, officer or director, past, present or
future as such, of the Company or of any predecessor or successor corporation, either directly or through the Company or any such predecessor or successor corporation, whether by virtue of any constitution, statute or rule of law, or by the
enforcement of any assessment or penalty or otherwise; it being expressly understood that this Indenture and the obligations issued hereunder are solely corporate obligations, and that no such personal liability whatever shall attach to, or is or
shall be incurred by, the incorporators, stockholders, officers or directors as such, of the Company or of any predecessor or successor corporation, or any of them, because of the creation of the indebtedness hereby authorized, or under or by reason
of the obligations, covenants or agreements contained in this Indenture or in any of the Securities or implied therefrom; and that any and all such personal liability of every name and nature, either at common law or in equity or by constitution or
statute, of, and any and all such rights and claims against, every such incorporator, stockholder, officer or director as such, because of the creation of the indebtedness hereby authorized, or under or by reason of the obligations, covenants or
agreements contained in this Indenture or in any of the Securities or implied therefrom, are hereby expressly waived and released as a condition of, and as a consideration for, the execution of this Indenture and the issuance of such Securities.

 ARTICLE 13 
 MISCELLANEOUS PROVISIONS 
  

	 	Section 13.01	Effect on Successors and Assigns. 

 All the covenants, stipulations, promises and agreements in this Indenture made by or on behalf of the Company shall bind its successors and assigns, whether so expressed or not. 

 

	 	Section 13.02	Actions by Successor. 

Any act or proceeding by any provision of this Indenture authorized or required to be done or performed by any board, committee or officer
of the Company shall and may be done 

  
 47.

 
and performed with like force and effect by the corresponding board, committee or officer of any corporation that shall at the time be the lawful successor of the Company. 

 

	 	Section 13.03	Surrender of Company Powers. 

 The Company by instrument in writing executed by authority of its Board of Directors and delivered to the Trustee may surrender any of the powers reserved to the Company, and thereupon such power so
surrendered shall terminate both as to the Company and as to any successor corporation. 
  

	 	Section 13.04	Notices. 

 Except as
otherwise expressly provided herein, any notice, request or demand that by any provision of this Indenture is required or permitted to be given, made or served by the Trustee, the Security Registrar, any paying or other agent under this Indenture,
the holders of Securities or any other Person pursuant to this Indenture to or on the Company, may be given or served by being in writing and sent by electronic transmission or deposited in first class mail, postage prepaid, addressed (until another
address is filed in writing by the Company with the Trustee), to the Company as follows: Exelixis, Inc., 210 East Grand Avenue, San Francisco, California 94080, Attention: Executive Vice President and General Counsel. Any notice, election, request
or demand by the Company or any Securityholder or by any other Person pursuant to this Indenture to or upon the Trustee shall be deemed to have been sufficiently given or made, for all purposes, if given or made in writing at the Corporate Trust
Office of the Trustee. 
  

	 	Section 13.05	Governing Law. 

 This
Indenture and each Security shall be deemed to be a contract made under the internal laws of the State of New York, and for all purposes shall be construed in accordance with the laws of said State, except to the extent that the Trust Indenture Act
is applicable. 
 In addition, the Company: (a) agrees that any suit, action or proceeding against it arising out of or
relating to this Indenture or any Securities, as the case may be, may be instituted in any U.S. federal court with applicable subject matter jurisdiction sitting in The City of New York; (b) waives, to the fullest extent permitted by applicable
law, any objection which it may now or hereafter have to the laying of venue of any such suit, action or proceeding, and any claim that any suit, action or proceeding in such a court has been brought in an inconvenient forum; and (c) submits to
the non-exclusive jurisdiction of such courts in any suit, action or proceeding. 
  

	 	Section 13.06	Treatment of Securities as Debt. 

 It is intended that the Securities will be treated as indebtedness and not as equity for federal income tax purposes. The provisions of this Indenture shall be interpreted to further this intention.

  
 48.

	 	Section 13.07	Certificates as to Conditions Precedent. 

 (a) Upon any application or demand by the Company to the Trustee to take any action under any of the provisions of this Indenture, the Company shall furnish to the Trustee an Officer’s
Certificate and an Opinion of Counsel or reliance letter, upon request, stating that all conditions precedent provided for in this Indenture (other than the certificate to be delivered pursuant to Section 13.12 or Section 314(a)(4) of the
Trust Indenture Act) relating to the proposed action have been complied with, except that in the case of any such application or demand as to which the furnishing of such documents is specifically required by any provision of this Indenture relating
to such particular application or demand, no additional certificate need be furnished; provided, however, that no Opinion of Counsel or reliance letter shall be required in connection with the issuance of Securities on the date on which the
Securities are originally issued or deemed issued as set forth on the face of such Securities. 
 (b) Each certificate or
opinion provided for in this Indenture and delivered to the Trustee with respect to compliance with a condition or covenant in this Indenture (other than the certificate to be delivered pursuant to Section 13.12 or Section 314(a)(4) of the
Trust Indenture Act) shall include (i) a statement that the Person making such certificate or opinion has read such covenant or condition; (ii) a brief statement as to the nature and scope of the examination or investigation upon which the
statements contained in such certificate or opinion are based; (iii) a statement that, in the opinion of such Person, he has made such examination or investigation as is reasonably necessary to enable him to express an informed opinion as to
whether or not such covenant or condition has been complied with; and (iv) a statement as to whether or not, in the opinion of such Person, such condition or covenant has been complied with. 

 

	 	Section 13.08	Payments on Business Days. 

Except as provided pursuant to Section 2.01 pursuant to a Board Resolution, and set forth in an Officer’s Certificate,
established in one or more indentures supplemental to this Indenture, or otherwise explicitly stated, in any case where the date of maturity of interest or principal of any Security, or the date for the repurchase of any Security or for the
redemption of any Security shall not be a Business Day, then payment of interest, principal (and premium, if any), redemption price or repurchase price due on such date may be made on the next succeeding Business Day with the same force and effect
as if made on the nominal date of maturity, repurchase or redemption, and no interest shall accrue for the period after such nominal date as a result of such delay. 
  

	 	Section 13.09	Conflict with Trust Indenture Act. 

 If and to the extent that any provision of this Indenture limits, qualifies or conflicts with the duties imposed by Sections 310 to 317, inclusive, of the Trust Indenture Act, such imposed duties shall
control. 

  
 49.

	 	Section 13.10	Counterparts. 

 This
Indenture may be executed in any number of counterparts, each of which shall be an original, but such counterparts shall together constitute but one and the same instrument. The exchange of copies of this Indenture and of signature pages by
facsimile or PDF transmission shall constitute effective execution and delivery of this Indenture as to the parties hereto and may be used in lieu of the original Indenture for all purposes. Signatures of the parties hereto transmitted by facsimile
or PDF shall be deemed to be their original signatures for all purposes. 
  

	 	Section 13.11	Separability. 

 In case
any one or more of the provisions contained in this Indenture or in the Securities of any series shall for any reason be held to be invalid, illegal or unenforceable in any respect, such invalidity, illegality or unenforceability shall not affect
any other provisions of this Indenture or of such Securities, but this Indenture and such Securities shall be construed as if such invalid or illegal or unenforceable provision had never been contained herein or therein. 

 

	 	Section 13.12	Compliance Certificates. 

The Company shall deliver to the Trustee, within 120 days after the end of each fiscal year during which any Securities of any series were
outstanding, an officer’s certificate stating whether or not the signers know of any Event of Default that occurred during such fiscal year. Such certificate shall contain a certification from the principal executive officer, principal
financial officer or principal accounting officer of the Company that a review has been conducted of the activities of the Company and the Company’s performance under this Indenture and that the Company has complied with all conditions and
covenants under this Indenture. For purposes of this Section 13.12, such compliance shall be determined without regard to any period of grace or requirement of notice provided under this Indenture. If the officer of the Company signing such
certificate has knowledge of such an Event of Default, the certificate shall describe any such Event of Default and its status. 
  

	 	Section 13.13	U.S.A. Patriot Act. 

 The
parties hereto acknowledge that in accordance with Section 326 of the U.S.A. Patriot Act, the Trustee, like all financial institutions and in order to help fight the funding of terrorism and money laundering, is required to obtain, verify, and
record information that identifies each person or legal entity that establishes a relationship or opens an account with the Trustee. The parties to this Indenture agree that they will provide the Trustee with such information as it may request in
order for the Trustee to satisfy the requirements of the U.S.A. Patriot Act. 
  

	 	Section 13.14	Force Majeure. 

 In no
event shall the Trustee, the Security Registrar, any paying agent or any other agent under this Indenture be responsible or liable for any failure or delay in the performance of its obligations hereunder arising out of or caused by, directly or
indirectly, forces beyond its 

  
 50.

 
control, including without limitation, strikes, work stoppages, accidents, acts of war or terrorism, civil or military disturbances, nuclear or natural catastrophes or acts of God, and
interruptions, loss or malfunctions or utilities, communications or computer (software and hardware) services; it being understood that the Trustee, the Security Registrar, any paying agent or any other agent under this Indenture shall use
reasonable efforts which are consistent with accepted practices in the banking industry to resume performance as soon as practicable under the circumstances. 
  

	 	Section 13.15	Table of Contents; Headings 

 The table of contents and headings of the articles and sections of this Indenture have been inserted for convenience of reference only, are not intended to be considered a part hereof, and will not modify
or restrict any of the terms or provisions hereof. 

  
 51.

 IN WITNESS WHEREOF, the parties hereto
have caused this Indenture to be duly executed all as of the day and year first above written. 
  

			
	EXELIXIS, INC.
		
	By:	 	 /s/ Michael M. Morrissey, Ph.D.

	Name:	 	Michael M. Morrissey, Ph.D.
	Title:	 	President and Chief Executive Officer
	
	 WELLS FARGO BANK, NATIONAL
ASSOCIATION,
 as Trustee

		
	By:	 	 /s/ Maddy Hall

	Name:	 	Maddy Hall
	Title:	 	Vice President

  
 52.

 CROSS-REFERENCE TABLE (1) 

 

			
	 Section of Trust Indenture Act of 1939, as Amended
	  	Section of Indenture
	 310(a)
	  	7.09
	 310(b)
	  	7.08
		  	7.10
	 310(c)
	  	Inapplicable
	 311(a)
	  	7.13
	 311(b)
	  	7.13
	 311(c)
	  	Inapplicable
	 312(a)
	  	5.01
		  	5.02(a)
	 312(b)
	  	5.02(c)
	 312(c)
	  	5.02(c)
	 313(a)
	  	5.04(a)
	 313(b)
	  	5.04(b)
	 313(c)
	  	5.04(a)
		  	5.04(b)
	 313(d)
	  	5.04(c)
	 314(a)
	  	5.03
		  	13.12
	 314(b)
	  	Inapplicable
	 314(c)
	  	13.07(a)
	 314(d)
	  	Inapplicable
	 314(e)
	  	13.07(b)
	 314(f)
	  	Inapplicable
	 315(a)
	  	7.01(a)
		  	7.01(b)
	 315(b)
	  	7.14
	 315(c)
	  	7.01
	 315(d)
	  	7.01(b)
	 315(e)
	  	6.07
	 316(a)
	  	6.06
		  	8.04
	 316(b)
	  	6.04
	 316(c)
	  	8.01
	 317(a)
	  	6.02
	 317(b)
	  	4.03
	 318(a)
	  	13.09

  

  
 53.

	(1)	This Cross-Reference Table does not constitute part of the Indenture and shall not have any bearing on the interpretation of any of its terms or provisions.

  
 54.First Supplemental Indenture, Dated as of August 14, 2012

 Exhibit 4.2 
 Exelixis, Inc. 
 as Issuer 

Wells Fargo Bank, National Association 
 as Trustee 
  

 
 First
Supplemental Indenture 
 Dated as of August 14, 2012 

to the Indenture dated as of 
 August 14, 2012 
  

 
 4.25%
Convertible Senior Subordinated Notes due 2019 

 TABLE OF CONTENTS 

 

							
	 	  	 	  	PAGE	 
		
	ARTICLE 1. DEFINITIONS AND OTHER PROVISIONS OF GENERAL APPLICATION	  	 	1	  
			
	Section 1.01	  	Scope of Supplemental Indenture	  	 	1	  
	Section 1.02	  	Definitions	  	 	2	  
	Section 1.03	  	References to Interest	  	 	14	  
	Section 1.04	  	Interpretation.	  	 	14	  
		
	ARTICLE 2. THE SECURITIES	  	 	14	  
			
	Section 2.01	  	Title and Terms; Payments	  	 	14	  
	Section 2.02	  	Forms	  	 	15	  
	Section 2.03	  	Transfer and Exchange	  	 	16	  
	Section 2.04	  	Payments on the Securities	  	 	19	  
		
	ARTICLE 3. FUNDAMENTAL CHANGE AND PURCHASES	  	 	20	  
			
	Section 3.01	  	Purchase at Option of Holders upon a Fundamental Change	  	 	20	  
	Section 3.02	  	Effect of Fundamental Change Purchase Notice	  	 	22	  
	Section 3.03	  	Withdrawal of Fundamental Change Purchase Notice	  	 	23	  
	Section 3.04	  	Deposit of Fundamental Change Purchase Price	  	 	23	  
	Section 3.05	  	Securities Purchased in Whole or in Part	  	 	23	  
	Section 3.06	  	Covenant to Comply with Applicable Laws upon Purchase of Securities	  	 	24	  
	Section 3.07	  	Repayment to the Company	  	 	24	  
		
	ARTICLE 4. CONVERSION	  	 	24	  
			
	Section 4.01	  	Right To Convert	  	 	24	  
	Section 4.02	  	Conversion Procedures	  	 	26	  
	Section 4.03	  	Settlement upon Conversion	  	 	28	  
	Section 4.04	  	Adjustment of Conversion Rate	  	 	31	  
	Section 4.05	  	Adjustment of Prices and Voluntary Adjustments	  	 	40	  
	Section 4.06	  	Adjustment to Conversion Rate upon Conversion in Connection with a Make-Whole	  			
		  	Fundamental Change	  	 	40	  
	Section 4.07	  	Effect of Recapitalization, Reclassification, Consolidation, Merger or Sale	  	 	42	  
	Section 4.08	  	Stock Issued upon Conversion	  	 	43	  
	Section 4.09	  	Responsibility of Trustee	  	 	44	  
	Section 4.10	  	Notice to Holders	  	 	44	  
		
	ARTICLE 5. SUBORDINATION	  	 	45	  
			
	Section 5.01	  	Agreement to Subordinate	  	 	45	  
	Section 5.02	  	Liquidation; Dissolution; Bankruptcy	  	 	45	  
	Section 5.03	  	Default on Senior Indebtedness	  	 	46	  
	Section 5.04	  	Acceleration of Securities	  	 	47	  
	Section 5.05	  	When Distribution Must Be Paid Over	  	 	47	  
	Section 5.06	  	Notice by Company	  	 	47	  
	Section 5.07	  	Subrogation	  	 	48	  
	Section 5.08	  	Relative Rights	  	 	48	  
	Section 5.09	  	Subordination May Not Be Impaired by Company	  	 	48	  
	Section 5.10	  	Distribution or Notice to Representative or Holders of Senior Indebtedness	  	 	48	  

  
 i 

							
	 Section 5.11
	  	Rights of Trustee and Paying Agent	  	 	49	  
	 Section 5.12
	  	Authorization to Effect Subordination; Filing Proof of Claim	  	 	49	  
	 Section 5.13
	  	Reliance and Amendments	  	 	49	  
	 Section 5.14
	  	No Layering	  	 	50	  
	 Section 5.15
	  	No Waiver of Subordination Provisions	  	 	50	  
		
	 ARTICLE 6. REDEMPTION
	  	 	50	  
			
	 Section 6.01
	  	General	  	 	50	  
	 Section 6.02
	  	Right to Redeem; Notices to Trustee	  	 	50	  
	 Section 6.03
	  	Selection of Securities to be Redeemed	  	 	51	  
	 Section 6.04
	  	Notice of Redemption	  	 	51	  
	 Section 6.05
	  	Effect of Notice of Redemption	  	 	52	  
	 Section 6.06
	  	Deposit of Redemption Price	  	 	52	  
	 Section 6.07
	  	Securities Redeemed in Part	  	 	53	  
		
	 ARTICLE 7. COLLATERAL SECURITY
	  	 	53	  
			
	 Section 7.01
	  	Collateral Security	  	 	53	  
		
	 ARTICLE 8. PARTICULAR COVENANTS OF THE COMPANY
	  	 	55	  
			
	 Section 8.01
	  	Payment of Principal, Interest, Redemption Price and Fundamental Change Purchase Price	  	 	55	  
	 Section 8.02
	  	Maintenance of Office or Agency	  	 	55	  
	 Section 8.03
	  	Appointments to Fill Vacancies in Trustee’s Office	  	 	56	  
	 Section 8.04
	  	Provisions as to Paying Agent	  	 	56	  
	 Section 8.05
	  	Existence	  	 	57	  
	 Section 8.06
	  	Reports	  	 	57	  
	 Section 8.07
	  	Pledge and Escrow Agreement	  	 	58	  
	 Section 8.08
	  	Officer’s Certificates	  	 	58	  
	 Section 8.09
	  	Further Instruments and Acts	  	 	58	  
		
	 ARTICLE 9. REMEDIES
	  	 	58	  
			
	 Section 9.01
	  	Amendments to the Base Indenture	  	 	58	  
	 Section 9.02
	  	Events of Default	  	 	58	  
	 Section 9.03
	  	Acceleration; Rescission and Annulment	  	 	60	  
	 Section 9.04
	  	Supplementary Interest	  	 	61	  
	 Section 9.05
	  	Waiver of Past Defaults	  	 	62	  
	 Section 9.06
	  	Control by Majority	  	 	62	  
	 Section 9.07
	  	Limitation on Suits	  	 	63	  
	 Section 9.08
	  	Rights of Holders to Receive Payment and to Convert	  	 	63	  
	 Section 9.09
	  	Collection of Indebtedness; Suit for Enforcement by Trustee	  	 	63	  
	 Section 9.10
	  	Trustee May Enforce Claims Without Possession of Securities	  	 	63	  
	 Section 9.11
	  	Trustee May File Proofs of Claim	  	 	64	  
	 Section 9.12
	  	Restoration of Rights and Remedies	  	 	64	  
	 Section 9.13
	  	Rights and Remedies Cumulative	  	 	64	  
	 Section 9.14
	  	Delay or Omission Not a Waiver	  	 	65	  
	 Section 9.15
	  	Priorities	  	 	65	  
	 Section 9.16
	  	Undertaking for Costs	  	 	65	  
	 Section 9.17
	  	Waiver of Stay, Extension and Usury Laws	  	 	66	  

  
 ii 

							
	 Section 9.18
	  	Notices from the Trustee	  	 	66	  
	 Section 9.19
	  	Statements as to Defaults	  	 	66	  
	 Section 9.20
	  	Supplementary Interest Notice	  	 	66	  
	 Section 9.21
	  	Standard of Care	  	 	66	  
		
	 ARTICLE 10. SATISFACTION AND DISCHARGE
	  	 	67	  
			
	 Section 10.01
	  	Inapplicability of Provisions of Base Indenture; Satisfaction and Discharge of the Indenture	  	 	67	  
	 Section 10.02
	  	Deposited Monies to Be Held in Trust by Trustee	  	 	67	  
	 Section 10.03
	  	Paying Agent to Repay Monies Held	  	 	68	  
	 Section 10.04
	  	Return of Unclaimed Monies	  	 	68	  
	 Section 10.05
	  	Reinstatement	  	 	68	  
		
	 ARTICLE 11. SUPPLEMENTAL INDENTURES
	  	 	68	  
			
	 Section 11.01
	  	Supplemental Indentures Without Consent of Holders	  	 	68	  
	 Section 11.02
	  	Supplemental Indentures With Consent of Holders	  	 	69	  
	 Section 11.03
	  	Notice of Amendment or Supplement	  	 	70	  
		
	 ARTICLE 12. SUCCESSOR COMPANY
	  	 	71	  
			
	 Section 12.01
	  	Consolidation, Merger and Sale of Assets	  	 	71	  
	 Section 12.02
	  	Company May Consolidate, Etc. on Certain Terms	  	 	71	  
	 Section 12.03
	  	Successor Corporation to Be Substituted	  	 	71	  
		
	 ARTICLE 13. MISCELLANEOUS
	  	 	71	  
			
	 Section 13.01
	  	[Reserved.]	  	 	71	  
	 Section 13.02
	  	Effect on Successors and Assigns	  	 	71	  
	 Section 13.03
	  	Governing Law; Waiver of Jury Trial	  	 	72	  
	 Section 13.04
	  	No Security Interest Created	  	 	72	  
	 Section 13.05
	  	Trust Indenture Act	  	 	72	  
	 Section 13.06
	  	Benefits of Supplemental Indenture	  	 	72	  
	 Section 13.07
	  	Calculations	  	 	72	  
	 Section 13.08
	  	Execution in Counterparts	  	 	73	  
	 Section 13.09
	  	Ratification of Base Indenture	  	 	73	  
	 Section 13.10
	  	The Trustee	  	 	73	  
			
		  	EXHIBIT	  			
			
	 Exhibit A
	  	Form of Security	  	 	A-1	  

  
 iii

 FIRST SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of
August 14, 2012, between Exelixis, Inc., a Delaware corporation (the “Company,” as more fully set forth in Section 1.01), and Wells Fargo Bank, National Association, a national banking association (the
“Trustee,” as more fully set forth in Section 1.01), as trustee under the Indenture, dated as of August 14, 2012, between the Company and the Trustee (as amended or supplemented from time to time in accordance with the
terms thereof, the “Base Indenture”). 
 RECITALS OF THE COMPANY 

WHEREAS, the Company executed and delivered the Base Indenture to the Trustee to provide, among other things, for the issuance, from time
to time, of the Company’s debt securities, in an unlimited aggregate principal amount, in one or more series to be established by the Company under, and authenticated and delivered as provided in, the Base Indenture; 

WHEREAS, Section 9.01(g) of the Base Indenture provides for the Company and the Trustee to enter into supplemental indentures to the
Base Indenture to establish the form and terms of Securities of any series as contemplated by Section 2.01 of the Base Indenture; 
 WHEREAS, the Board of Directors has duly adopted resolutions authorizing the Company to execute and deliver this Supplemental Indenture; 

WHEREAS, pursuant to the terms of the Base Indenture, the Company has authorized the creation and issuance under this Supplemental
Indenture of its 4.25% Convertible Senior Subordinated Notes due 2019 (the “Securities”), the form and substance of such Securities and the terms, provisions and conditions thereof to be set forth as provided in the Base Indenture
and this Supplemental Indenture; and 
 WHEREAS, the Company has requested that the Trustee execute and deliver this
Supplemental Indenture, and that all requirements necessary to make (i) this Supplemental Indenture a valid instrument in accordance with its terms, and (ii) the Securities, when executed by the Company and authenticated and delivered by
the Trustee, the valid obligations of the Company have been performed, and the execution and delivery of this Supplemental Indenture have been duly authorized in all respects. 
 NOW, THEREFORE, THIS SUPPLEMENTAL INDENTURE WITNESSETH, for and in consideration of the premises and the purchases of the Securities by the Holders thereof, it is mutually agreed, for the benefit of the
Company and the equal and proportionate benefit of all Holders, as follows: 
 ARTICLE 1. 

DEFINITIONS AND OTHER PROVISIONS OF GENERAL APPLICATION 
 Section 1.01 Scope of Supplemental Indenture. The changes, modifications and supplements to the Base Indenture effected by this Supplemental Indenture shall be applicable only with respect to, and
shall govern only the terms of (and only the rights of the Holders and the obligations of the Company with respect to), the Securities, which may be issued from time to time, and shall not apply to any other securities that may be issued under the
Base Indenture (or govern the rights of the Holders or the obligations of the Company with respect to any such 

  
 1 

 
other securities) unless a supplemental indenture with respect to such other securities specifically incorporates such changes, modifications and supplements. The provisions of this Supplemental
Indenture shall, with respect to the Securities, supersede any corresponding provisions in the Base Indenture. Subject to the preceding sentence, and except as otherwise provided herein, the provisions of the Base Indenture shall apply to the
Securities and govern the rights of the Holders of the Securities and the obligations of the Company and the Trustee with respect thereto. 
 Section 1.02 Definitions. For all purposes of the Indenture, except as otherwise expressly provided or unless the context otherwise requires: 

(i) the terms defined in this Article 1 shall have the meanings assigned to them in this Article 1 and include
the plural as well as the singular; and 
 (ii) all words, terms and phrases defined in the Base Indenture (but
not otherwise defined herein) shall have the same meanings as in the Base Indenture. 
 “Additional Shares” has
the meaning specified in Section 4.06(a) hereof. 
 “Affiliate” means, with respect to any specified
Person, any other Person directly or indirectly controlling or controlled by or under direct or indirect common control with such specified Person. For the purposes of this definition, “control” means, when used with respect to any
specified Person, the power to direct the management and policies of such Person, directly or indirectly, whether through the ownership of voting securities, by contract or otherwise; and the terms “controlling” and “controlled”
have meanings correlative to the foregoing. 
 “Agent Members” has the meaning specified in
Section 2.02(c) hereof. 
 “Applicable Procedures” of a Depositary means, with respect to any matter at
any time, the policies and procedures of such Depositary, if any, that are applicable to such matter at such time. 

“Averaging Period” has the meaning specified in Section 4.04(e) hereof. 

“Base Indenture” has the meaning specified in the first paragraph of this Supplemental Indenture, as such instruments
may be supplemented from time to time by one or more indentures supplemental thereto, including this Supplemental Indenture, entered into pursuant to the applicable provisions of the Base Indenture, including, for all purposes of the Base Indenture,
this Supplemental Indenture and any such other supplemental indenture, the provisions of the Trust Indenture Act that are deemed to be a part of and govern the Base Indenture, this Supplemental Indenture and any other such supplemental indenture,
respectively. 
 “Bid Solicitation Agent” means the Company or an independent nationally recognized investment
banking firm as may be appointed, from time to time, by the Company to solicit bids for the Trading Price of the Securities in accordance with Section 4.01(b)(2) hereof. 
 “Board of Directors” means, notwithstanding anything to the contrary in Section 1.01 of the Base Indenture, the board of directors of the Company or a committee of such board of
directors. 

  
 2 

 “Business Day” means, notwithstanding anything to the contrary in
Section 1.01 of the Base Indenture, any day other than a Saturday, a Sunday or a day on which the Federal Reserve Bank of New York or place of payment is authorized or required by law or executive order to close or to be closed. 

“Capital Stock” means, for any Person, any and all shares, interests, rights to purchase, warrants, options,
participations or other equivalents of or interests in (however designated) the equity of such Person, but excluding any debt securities convertible into such equity. 
 “Cash Settlement” has the meaning set forth in Section 4.03(a) hereof. 
 “Cash Settlement Averaging Period” means, with respect to any Security, the 50 consecutive VWAP Trading Day period beginning on, and including, the third VWAP Trading Day immediately
following the related Conversion Date; provided that, 
 (a) for any Security having a Conversion Date occurring during
the period beginning on, and including, May 29, 2019, and ending at the Close of Business on the second Scheduled Trading Day immediately prior to the Maturity Date, the “Cash Settlement Averaging Period” means the 50 consecutive VWAP
Trading Days beginning on, and including, the 52nd Scheduled Trading Day immediately preceding the Maturity Date or, if such day is not a VWAP Trading Day, the immediately following VWAP Trading Day; and 

(b) for any Security having a Conversion Date occurring on or after the date the Company has delivered a Redemption Notice as described
in Article 6, the “Cash Settlement Averaging Period” means the 50 consecutive VWAP Trading Days prior to the Redemption Date or, if such day is not a VWAP Trading Day, the immediately following VWAP Trading Day. 

“Clause A Distribution” has the meaning specified in Section 4.04(c) hereof. 

“Clause B Distribution” has the meaning specified in Section 4.04(c) hereof. 

“Clause C Distribution” has the meaning specified in Section 4.04(c) hereof. 

“Close of Business” means 5:00 p.m., New York City time. 

“Combination Settlement” has the meaning specified in Section 4.03(a) hereof. 

“Common Equity” of any Person means the Capital Stock of such Person that is generally entitled (a) to vote in the
election of directors of such Person or (b) if such Person is not a corporation, to vote or otherwise participate in the selection of the governing body, partners, managers or others that will control the management or policies of such Person.

 “Common Stock” means, subject to Section 4.07, the shares of common stock, par value $0.001 per share,
of the Company authorized at the date of this instrument as originally executed or shares of any class or classes of common stock resulting from any reclassification or reclassifications thereof; provided, however, that if at any time
there shall be more than one such resulting class, the shares so issuable on conversion of Securities shall include shares of all such classes, and the shares of each such class then so issuable shall be substantially in the proportion

  
 3 

 
which the total number of shares of such class resulting from all such reclassifications bears to the total number of shares of all such classes resulting from all such reclassifications.

 “common stock” includes any stock of any class of capital stock which has no preference in respect of
dividends or of amounts payable in the event of any voluntary or involuntary liquidation, dissolution or winding-up of the issuer thereof and which is not subject to redemption by the issuer thereof. 

“Company” has the meaning specified in the first paragraph of this Supplemental Indenture, notwithstanding anything to
the contrary in Section 1.01 of the Base Indenture, and subject to the provisions of Section 12.02, shall include its successors and assigns. 
 “Conversion Agent” means the office or agency designated by the Company where Securities may be presented for conversion. 

“Conversion Date” has the meaning specified in Section 4.02(b) hereof. 

“Conversion Notice” has the meaning specified in Section 4.02(b) hereof. 

“Conversion Obligation” has the meaning specified in Section 4.01(a) hereof. 

“Conversion Price” means, in respect of each Security, as of any date, $1,000 divided by the Conversion Rate in
effect on such date. 
 “Conversion Rate” means initially 188.2353 shares of Common Stock per $1,000 principal
amount of Securities, subject to adjustment as set forth herein. 
 “Custodian” means the Trustee, as custodian
with respect to the Securities (so long as the Securities constitute Global Securities), or any successor entity. 

“Daily Conversion Value” means, for any of the 50 consecutive VWAP Trading Days during any Cash Settlement Averaging
Period, one-fiftieth (1/50th) of the product of (i) the Conversion Rate in effect on such VWAP Trading Day and (ii) the Daily VWAP on such VWAP Trading Day. 
 “Daily Settlement Amount” means, for any of the 50 consecutive VWAP Trading Days during a Cash Settlement Averaging Period, an amount consisting of: 

(a) cash equal to the lesser of (i) the Daily Specified Dollar Amount and (ii) the Daily Conversion Value for such Trading Day;
and 
 (b) if the Daily Conversion Value exceeds the Daily Specified Dollar Amount, a number of shares of Common Stock equal to
(i) the difference between the Daily Conversion Value and the Daily Specified Dollar Amount, divided by (ii) the Daily VWAP for such Trading Day. 
 “Daily Specified Dollar Amount” means the quotient of the Specified Dollar Amount divided by 50. 

  
 4 

 “Daily VWAP” means, for any VWAP Trading Day, the per-share volume-weighted
average price as displayed under the heading “Bloomberg VWAP” on Bloomberg page “EXEL.Q <equity> AQR” (or its equivalent successor if such page is not available) in respect of the period from the scheduled open of trading
until the scheduled close of trading of the primary trading session on such VWAP Trading Day (or if such volume-weighted average price is unavailable, the market value of one share of the Common Stock on such VWAP Trading Day determined, using a
volume-weighted average method, by a nationally recognized independent investment banking firm retained for this purpose by the Company). The “daily VWAP” will be determined without regard to after-hours trading or any other trading
outside of the regular trading session’s trading hours. 
 “Default” means any event that is, or with the
passage of time or the giving of notice or both would be, an Event of Default. 
 “Deerfield Notes” means the
Company’s secured convertible notes sold to Deerfield Private Design Fund, L.P. and Deerfield Private Design International, L.P. pursuant to a Note Purchase Agreement, dated as of June 2, 2010, including any related notes, guarantees,
collateral documents, instruments and agreements executed in connection therewith and in each case, as amended, extended, supplemented or modified from time to time. 
 “Distributed Property” has the meaning specified in Section 4.04(c) hereof. 
 “EDGAR” means the Electronic Data Gathering, Analysis, and Retrieval system or any successor thereto. 
 “Effective Date” has the meaning specified in Section 4.06(c) hereof. 
 “Event of Default” has the meaning, notwithstanding anything to the contrary in Section 1.01 of the Base Indenture, specified in Section 9.02 hereof. 

“Escrow Account” means the escrow account established pursuant to the Pledge and Escrow Agreement. 

“Escrow Agent” means Wells Fargo Bank, National Association, in its capacity as escrow agent under the Pledge and Escrow
Agreement, and any permitted successors thereto. 
 “Ex-Dividend Date” means, except to the extent otherwise
provided under Section 4.04(c) hereof, the first date on which shares of the Common Stock trade on the applicable exchange or in the applicable market, regular way, without the right to receive the issuance, dividend or distribution in
question. 
 “Form of Assignment and Transfer” means the “Form of Assignment and Transfer” attached
as Attachment 3 to the Form of Security attached hereto as Exhibit A. 
 “Form of Fundamental Change
Purchase Notice” means the “Form of Fundamental Change Purchase Notice” attached as Attachment 2 to the Form of Security attached hereto as Exhibit A. 

  
 5 

 “Form of Notice of Conversion” means the “Form of Notice of
Conversion” attached as Attachment 1 to the Form of Security attached hereto as Exhibit A. 

“Fundamental Change” shall be deemed to have occurred at the time after the Securities are originally issued if any of
the following occurs: 
 (1) a “person” or “group” within the meaning of Section 13(d) of the Exchange
Act, other than the Company, its Subsidiaries and its and their employee benefit plans, files a Schedule TO or any schedule, form or report under the Exchange Act disclosing, or the Company otherwise becomes aware, that such person or group has
become the direct or indirect “beneficial owner,” as defined in Rule 13d-3 under the Exchange Act, of its common equity representing more than 50% of the voting power of all classes of shares of capital stock entitled to vote generally in
the election of the Board of Directors; 
 (2) the consummation of (A) any recapitalization, reclassification or change of
the Company’s common stock (other than changes resulting from a subdivision or combination) as a result of which the Company’s common stock would be converted into, or exchanged for, cash, stock, other securities, other property or assets;
(B) any share exchange, consolidation or merger of the Company pursuant to which its common stock will be converted into, or exchanged for, cash, stock, other securities, other property or assets; or (C) any sale, lease or other transfer
in one transaction or a series of transactions of all or substantially all of the consolidated assets of the Company and its Subsidiaries, taken as a whole, to any Person other than one of the Company’s Subsidiaries; provided,
however, that a transaction described in clause (A) or clause (B) in which the holders of all classes of the Company’s capital stock entitled to vote generally in the election of directors immediately prior to such transaction
have the right to exercise more than 50% of the total voting power of all shares of capital stock of the continuing or surviving corporation or transferee or the parent thereof entitled to vote generally in elections of directors of such Person
immediately after such transaction in substantially the same proportions (relative to each other and with respect to the securities received in such transaction) as such ownership immediately prior to such transaction shall not be a Fundamental
Change pursuant to this clause (2); 
 (3) the Company’s stockholders approve any plan or proposal for the liquidation or
dissolution of the Company; or 
 (4) the Common Stock (or other common stock underlying the Securities) ceases to be listed on
The NASDAQ Global Select Market, the NASDAQ Global Market or The New York Stock Exchange (or any of their respective successors); 

provided, however, that in the case of a transaction or event described in clause (1) or (2) above, if at least 90% of the
consideration received or to be received by holders of the Common Stock (excluding cash payments for fractional shares or pursuant to dissenters’ rights) in the transaction or transactions that would otherwise constitute a “Fundamental
Change” consists of shares of common stock that are traded on The NASDAQ Global Select Market, the NASDAQ Global Market or The New York Stock Exchange (or any of their respective successors) or that will be so traded when issued or exchanged in
connection with the transaction that would otherwise constitute a “Fundamental Change” under clause (1) or (2) above, and as a result of such 

  
 6 

 
transaction or transactions, the Securities become convertible into or based on such consideration received or to be received by holders of the Common Stock, excluding cash payments for
fractional shares or pursuant to dissenters’ rights (subject to settlement in accordance with the provisions of Sections 4.03, 4.04 and 4.06 hereof), such event shall not be a “Fundamental Change” and, for the avoidance of doubt, an
event that is not considered a “Fundamental Change” pursuant to this proviso shall not be a “Fundamental Change” solely because such event could also be described by clause (1) or (2) above. 

“Fundamental Change Company Notice” has the meaning specified in Section 3.01(b) hereof. 

“Fundamental Change Expiration Time” has the meaning specified in Section 3.01(a) hereof. 

“Fundamental Change Purchase Date” has the meaning specified in Section 3.01(a) hereof. 

“Fundamental Change Purchase Notice” has the meaning specified in Section 3.01(a) hereof. 

“Fundamental Change Purchase Price” has the meaning specified in Section 3.01(a) hereof. 

“Government Securities” means noncallable direct obligations of, or noncallable obligations the payment of principal of
and interest on which are unconditionally guaranteed by, the United States of America. 
 “Guarantee” of or by
any Person (the “guarantor”) means any obligation, contingent or otherwise, of the guarantor guaranteeing or having the economic effect of guaranteeing any Indebtedness or other obligation of any other Person (the “primary
obligor”) in any manner, whether directly or indirectly, and including any obligation of the guarantor, direct or indirect: 
 (1) to purchase or pay (or advance or supply funds for the purchase or payment of) such Indebtedness or other obligation or to purchase (or to advance or supply funds for the purchase of) any security for
the payment thereof; 
 (2) to purchase or lease property, securities or services for the purpose of assuring the owner of such
Indebtedness or other obligation of the payment thereof; 
 (3) to maintain working capital, equity capital or any other
financial statement condition or liquidity of the primary obligor so as to enable the primary obligor to pay such Indebtedness or other obligation; or 
 (4) as an account party in respect of any letter of credit or letter of guaranty issued to support such Indebtedness or obligation; 
 provided, that the term “Guarantee” will not include endorsements for collection or deposit in the ordinary course of business. In any computation of the Indebtedness or other liabilities
of the 

  
 7 

 
obligor under any Guarantee, the Indebtedness or other obligations that are the subject of such Guarantee will be assumed to be direct obligations of such obligor. 

“Hedging Obligations” means, with respect to any specified Person, the obligations of such Person under: 

(1) interest rate swap agreements (whether from fixed to floating or from floating to fixed), interest rate cap agreements and interest
rate collar agreements; 
 (2) other agreements or arrangements designed to manage interest rates or interest rate risk; and

 (3) commodity swap agreements, commodity cap agreements, commodity collar agreements, foreign exchange contracts, currency
swap agreements or any other agreements or arrangements designed to protect such Person against fluctuations in, or providing for the transfer or mitigation of risks related to, currency exchange rates or commodity prices, in each case, either
generally or under specific contingencies. 
 “Holder” means the Person in whose name a Security is registered
on the books of the Registrar. 
 “Indebtedness” of any Person means, any indebtedness of such Person
(excluding accrued expenses and commercial letters of credit, trade payables or similar obligations to a trade creditor accrued in the ordinary course of business), whether or not contingent, without duplication: 

(1) all Obligations of such Person for borrowed money (including any such obligations convertible into capital stock or other
securities); 
 (2) all Obligations of such Person evidenced by bonds, debentures, notes or similar instruments or letters of
credit (or, without duplication, reimbursement agreements in respect thereof); 
 (3) all Indebtedness of others secured by (or
for which the holder of such Indebtedness has an existing right, contingent or otherwise, to be secured by) any Lien on property owned or acquired by such Person, whether or not the Indebtedness secured thereby has been assumed; 

(4) all Guarantees by such Person of Indebtedness of others; 
 (5) all obligations, contingent or otherwise, of such Person as an account party in respect of letters of credit and letters of guaranty; 

(6) all obligations, contingent or otherwise, of such Person in respect of bankers’ acceptances; and 

(7) representing any Hedging Obligations. 

  
 8 

 The Indebtedness of any Person shall include the Indebtedness of any other entity (including
any partnership in which such Person is a general partner) to the extent such Person is liable therefor as a result of such Person’s ownership interest in or other relationship with such entity, except to the extent the terms of such
Indebtedness provide that such Person is not liable therefor. 
 “Indenture” means, notwithstanding anything to
the contrary in Section 1.01 of the Base Indenture, the Base Indenture, as originally executed and as supplemented from time to time by one or more indentures supplemental thereto, including this Supplemental Indenture, entered into pursuant to
the applicable provisions of the Indenture, including, for all purposes of the Base Indenture, this Supplemental Indenture and any such other supplemental indenture, the provisions of the Trust Indenture Act that are deemed to be a part of and
govern the Base Indenture, this Supplemental Indenture and any other such supplemental indenture, respectively. 

“Interest Payment Date” means, with respect to the payment of interest on the Securities and notwithstanding anything to
the contrary in Section 1.01 of the Base Indenture, each February 15 and August 15 of each year, beginning on February 15, 2013. 
 “Issue Date” means, with respect to the Securities, August 14, 2012. 
 “Issuer Free Writing Prospectus Term Sheet” means the Final Term Sheet, dated August 9, 2012, relating to the Preliminary Prospectus Supplement. 

“Last Reported Sale Price” of the Common Stock for any Trading Day means the closing sale price per share (or, if no
closing sale price is reported, the average of the last bid and last ask prices or, if more than one in either case, the average of the average last bid and the average last ask prices) on that Trading Day as reported in composite transactions for
the principal U.S. national or regional securities exchange on which the Common Stock is traded. If the Common Stock is not listed for trading on a U.S. national or regional securities exchange on the relevant trading day, the “Last Reported
Sale Price” will be the last quoted bid price for the Common Stock in the over-the-counter market on the relevant date as reported by OTC Markets Group Inc. or a similar organization. If the Common Stock is not so quoted, the “Last
Reported Sale Price” will be the average of the mid-point of the last bid and last ask prices for the Common Stock on the relevant trading day from each of at least three nationally recognized independent investment banking firms selected by
the Company for this purpose. The “Last Reported Sale Price” will be determined without reference to after hours trading or any other trading outside of the regular trading session. Any such determination will be conclusive absent manifest
error. 
 “Lien” means any mortgage, pledge, security interest, encumbrance, lien or charge of any kind
(including any conditional sale or other title retention agreement or lease in the nature thereof or any agreement to give any security interest). 
 “Make-Whole Fundamental Change” means any event that (i) is a Fundamental Change or (ii) would be a Fundamental Change, but for the proviso in clause (2) of the
definition thereof. 

  
 9 

 “Market Disruption Event” means, if the Common Stock is listed for trading
on The NASDAQ Global Select Market or listed on another U.S. national or regional securities exchange, the occurrence or existence during the one-half-hour period ending on the scheduled close of trading on any Trading Day of any material suspension
or limitation imposed on trading (by reason of movements in price exceeding limits permitted by the stock exchange or otherwise) in the Common Stock or in any options, contracts or futures contracts relating to the Common Stock. 

“Maturity Date” means, with respect to any Security and the payment of the principal amount thereof, August 15,
2019. 
 “Measurement Period” has the meaning specified in Section 4.01(b) hereof. 

“Merger Event” has the meaning specified in Section 4.07(a). 

“Merger Transaction” has the meaning specified in Section 12.02. 

“Nonpayment Default” has the meaning specified in Section 5.03(a) hereof. 

“Notice of Default” has the meaning specified in Section 9.02(g) hereof. 

“Obligations” means any principal, interest, penalties, fees, premiums, make whole amounts, indemnifications,
reimbursements, damages and other costs, expenses and liabilities payable under the documentation governing any Indebtedness. 

“Offer Expiration Date” has the meaning specified in Section 4.04(e) hereof. 

“Open of Business” means 9:00 a.m., New York City time. 

“Outstanding” means, with respect to the Securities, notwithstanding anything to the contrary in Section 1.01 of
the Base Indenture, any Securities authenticated by the Trustee except (i) Securities cancelled by it, (ii) Securities delivered to it for cancellation, (iii) Securities redeemed by the Company pursuant to Article 6, and (iv)(A)
Securities replaced pursuant to Section 2.07 of the Base Indenture, on and after the time such Security is replaced (unless the Trustee and the Company receive proof satisfactory to them that such Security is held by a bona fide purchaser),
(B) Securities converted pursuant to Article 4 hereof, on and after their Conversion Date, (C) any and all Securities that have become due and payable if the Paying Agent holds, in accordance with this Indenture, money sufficient to pay
all of the Securities then payable, and (D) any and all Securities owned by the Company or any other obligor upon the Securities or any Affiliate of the Company or of such other obligor, except that in determining whether the Trustee shall be
protected in relying upon any request, demand, authorization, direction, notice, consent or waiver or other action that is to be made by a requisite principal amount of Outstanding Securities, such Securities which a Responsible Officer of the
Trustee knows to be so owned shall be disregarded. 
 “Paying Agent” means the Person authorized by the Company
to pay the principal amount of, interest on, Redemption Price of or Fundamental Change Purchase Price of, any Securities on behalf of the Company. 

  
 10 

 “Payment Blockage Notice” has the meaning specified in Section 5.03(a)
hereof. 
 “Payment Default” has the meaning specified in Section 5.03(a) hereof. 

“Permitted Money Market Fund” means any registered investment company that meets the conditions of paragraphs (c)(2),
(c)(3) and (c) (4) of Rule 2a-7 under the Investment Company Act of 1940, as amended, that has assets consisting of cash, securities of the U.S. government and permitted government-sponsored enterprises and privately issued money market
securities that have been rated by at least one “nationally recognized statistical rating organization” (as that term is used in Section 15E of the Exchange Act) and received the highest credit rating (as of the Issue Date of the
initial Securities issued hereunder, A1 in the case of Standard & Poor’s Ratings Service and P1 in the case of Moody’s Investor Service, Inc.) from each nationally recognized statistical rating organization that has rated them.

 “Permitted Money Market Securities” means money market securities issued by Permitted Money Market Funds.

 “Physical Securities” means any non-Global Security issued pursuant to Section 2.03 hereof that is in
definitive, fully registered form, without interest coupons. 
 “Physical Settlement” has the meaning specified
in Section 4.03(a) hereof. 
 “Pledge and Escrow Agreement” means the Pledge and Escrow Agreement, dated
as of August 14, 2012, by and among the Company, the Trustee and the Escrow Agent, as amended, extended, supplemented or modified from time to time. 
 “Pledged Collateral” means any cash held in the Escrow Account in accordance with the Pledge and Escrow Agreement and any Pledged Securities. 

“Pledged Securities” means the Government Securities or Permitted Money Market Securities to be purchased by the Company
and held in the Escrow Account in accordance with the Pledge and Escrow Agreement. 
 “Preliminary Prospectus
Supplement” means the Preliminary Prospectus Supplement, dated August 6, 2012, relating to the Securities. 

“Redemption Date” means the date specified for redemption of the Securities in accordance with the terms of the
Securities and Article 6. 
 “Redemption Notice” has the meaning specified in Section 6.04. 

“Redemption Price” has the meaning specified in Section 6.02(b). 

“Reference Property” has the meaning specified in Section 4.07(a) hereof. 

“Regular Record Date” means, with respect to any Interest Payment Date, the February 1 (whether or not a Business
Day) or the August 1 (whether or not a Business Day), as the case may be, immediately preceding such Interest Payment Date. 

  
 11 

 “Reporting Event of Default” has the meaning specified in
Section 9.04(a) hereof. 
 “Representative” means the agent or representative for the Senior Indebtedness,
provided that if no Representative has been appointed under the instrument governing the Senior Indebtedness, any holder or group of holders of the Senior Indebtedness certifying that it holds a percentage of the Senior Indebtedness
sufficient to cause the acceleration thereof will be deemed a Representative. 
 “Scheduled Trading Day” means
a day that is scheduled to be a Trading Day on the principal U.S. national or regional securities exchange or market on which the Common Stock is listed or admitted for trading. If the Common Stock is not so listed or admitted for trading,
“Scheduled Trading Day” means a Business Day. 
 “Security” or “Securities” has the
meaning specified in the fourth paragraph of the Recitals of this Supplemental Indenture, notwithstanding anything to the contrary in Section 1.01 of the Base Indenture. 
 “Senior Indebtedness” means all the Company’s Indebtedness outstanding from time to time under the Deerfield Notes and all obligations with respect to any of the foregoing.

 “Settlement Amount” has the meaning specified in Section 4.03(a)(3) hereof. 

“Settlement Election” has the meaning specified in Section 4.03(a) hereof. 

“Settlement Election Notice” has the meaning specified in Section 4.03(a)(2) hereof. 

“Settlement Method” means, with respect to any conversion of Securities, Physical Settlement, Cash Settlement or
Combination Settlement, as elected by the Company. 
 “Significant Subsidiary” means, with respect to any
Person, a Subsidiary of such Person that would constitute a “significant subsidiary” as such term is defined in Article 1, Rule 1-02 of Regulation S-X under the Exchange Act, as in effect on the original date of issuance of the Securities;
provided that, in the case of a Subsidiary that meets the criteria of clause (3) of the definition thereof but not clause (1) or (2) thereof, such Subsidiary shall not be deemed to be a Significant Subsidiary unless such
Subsidiary’s income from continuing operations before income taxes, extraordinary items and cumulative effect of a change in accounting principle exclusive of amounts attributable to any non-controlling interest for the last completed fiscal
year prior to the date of such determination exceeds $25,000,000. 
 “Specified Dollar Amount” means an amount
of cash per $1,000 principal amount of converted Securities equal to $1,000; provided that in the event of the delivery of any Settlement Election Notice specifying a different Specified Dollar Amount pursuant to Section 4.03(a)(1)
hereof, during the period during which such Settlement Election Notice is effective, the Specified Dollar Amount shall be as specified in such Settlement Election Notice. 
 “Specified Dollar Amount Election” has the meaning specified in Section 4.03(a)(1) hereof. 

  
 12 

 “Spin-Off” has the meaning specified in Section 4.04(c) hereof.

 “Stock Price” has the meaning specified in Section 4.06(c) hereof. 

“Successor Company” has the meaning specified in Section 12.02(a) hereof. 

“Supplemental Indenture” has the meaning specified in the first paragraph hereof, as such instrument may be supplemented
from time to time by one or more indentures supplemental thereto, entered into pursuant to the applicable provisions of the Base Indenture and the Supplemental Indenture, including, for all purposes of this Supplemental Indenture and any such other
supplemental indenture, the provisions of the Trust Indenture Act that are deemed to be a part of and govern the Base Indenture, this Supplemental Indenture and any other such supplemental indenture, respectively. 

“Supplementary Interest” has the meaning specified in Section 9.04(a) hereof. 

“Trading Day” means a Scheduled Trading Day on which (i) trading in the Common Stock generally occurs on The NASDAQ
Global Select Market or, if the Common Stock is not then listed on The NASDAQ Global Select Market, on the principal other U.S. national or regional securities exchange on which the Common Stock is then listed or, if the Common Stock is not then
listed on a U.S. national or regional securities exchange, on the principal other market on which the Common Stock is then traded, and (ii) there is no Market Disruption Event. If the Common Stock is not so listed or traded, “Trading
Day” means a “Business Day.” 
 “Trading Price” of the Securities on any date of determination
means the average of the secondary market bid quotations obtained by the Bid Solicitation Agent for $5,000,000 principal amount of the Securities at approximately 3:30 p.m., New York City time, on such Trading Day from three independent nationally
recognized securities dealers selected by the Company; provided that, if three such bids cannot reasonably be obtained by the Bid Solicitation Agent but two such bids are obtained, then the average of the two bids shall be used, and if only
one such bid can reasonably be obtained by the Bid Solicitation Agent, that one bid shall be used. If the Bid Solicitation Agent cannot reasonably obtain at least one bid for $5.0 million principal amount of the Securities from a nationally
recognized securities dealer, then the Trading Price per $1,000 principal amount of Securities will be deemed to be less than 98% of the product of (i) the Conversion Rate in effect on such Trading Day and (ii) the Last Reported Sale Price
of the Common Stock on such Trading Day. Any such determination will be conclusive absent manifest error. 

“Trustee” means the Person named as the “Trustee” in the first paragraph of this Supplemental Indenture until
a successor Trustee shall have become such pursuant to the applicable provisions of the Base Indenture and this Supplemental Indenture, and thereafter “Trustee” shall mean or include each Person who is then a Trustee hereunder. 

“Unit of Reference Property” has the meaning specified in Section 4.07(a) hereof. 

“U.S.” means the United States of America. 
 “Valuation Period” has the meaning specified in Section 4.04(c) hereof. 

  
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 “VWAP Market Disruption Event” means (i) a failure by the principal
U.S. national or regional securities exchange or market on which the Common Stock is listed or admitted to trading to open for trading during its regular trading session or (ii) the occurrence or existence, prior to 1:00 p.m., New York City
time, on any Scheduled Trading Day for the Common Stock for more than a one half-hour period in the aggregate during regular trading hours, of any suspension or limitation imposed on trading (by reason of movements in price exceeding limits
permitted by the relevant securities exchange or otherwise) in the Common Stock or in any options, contracts or future contracts relating to the Common Stock. 
 “VWAP Trading Day” means a Scheduled Trading Day on which (i) there is no VWAP Market Disruption Event and (ii) trading in the Common Stock generally occurs on The NASDAQ Global
Select Market or, if the Common Stock is not then listed on The NASDAQ Global Select Market, on the principal other U.S. national or regional securities exchange on which the Common Stock is then listed or, if the Common Stock is not then listed on
a U.S. national or regional securities exchange, on the principal other market on which the Common Stock is then traded. If the Common Stock is not so listed or traded, “Trading Day” means a “Business Day.” 

Section 1.03 References to Interest. Any reference to interest on, or in respect of, any Security in the Indenture shall be deemed
to include Supplementary Interest if, in such context, Supplementary Interest is, was or would be payable pursuant to Section 9.04. Any express mention of the payment of Supplementary Interest in any provision hereof shall not be construed as
excluding Supplementary Interest in those provisions hereof where such express mention is not made. 
 Section 1.04
Interpretation. The terms “include” and “including” and words of similar import are to be construed as non-exclusive (so that, by way of example, “including” shall mean “including without limitation”).

 ARTICLE 2. 
 THE SECURITIES 
 Section 2.01 Title and Terms; Payments. 

(a) Establishment; Designation. Pursuant to Section 2.01 of the Base Indenture, there is hereby established and authorized a
new series of Securities under the Indenture, which series of Securities shall be designated the “4.25% Convertible Senior Subordinated Notes due 2019.” 
 (b) Initial Issuance. Subject to Section 2.01(c) hereof, the aggregate principal amount of Securities that may initially be authenticated and delivered under the Indenture on the Issue Date is
limited to $287,500,000. In addition, subject to Section 2.01(c) hereof, the Company may execute, and the Trustee may authenticate and deliver, in each case, in accordance with Section 2.04 of the Base Indenture, an unlimited aggregate
principal amount of additional Securities upon the registration or transfer, exchange of, purchase or conversion of Securities pursuant to the relevant sections of the Base Indenture and this Supplemental Indenture. 

  
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 (c) Further Issues. The Company may, without notice to or the consent of the Holders,
issue additional Securities under the Indenture with the same terms and the same CUSIP number as the Securities initially issued under the Indenture in an unlimited aggregate principal amount, including placing a portion of the proceeds of such
additional Securities in an escrow account to secure any interest payments on or before August 15, 2015 for such additional Securities in accordance with the terms and conditions of the Pledge and Escrow Agreement; provided, that the
Company may issue such additional Securities only if they are part of the same issue as the Securities initially issued hereunder for U.S. federal income tax purposes. Any such additional Securities will, for all purposes of the Indenture, including
waivers, amendments and offers to purchase, be treated as part of the same series as the Securities initially issued under the Indenture. 
 (d) Purchases. The Company and its Subsidiaries may from time to time repurchase Securities in open market purchases in negotiated transactions or otherwise without giving prior notice to the
Holders. Any Securities purchased by the Company or any of its Subsidiaries pursuant to the foregoing sentence or otherwise (other than Securities purchased pursuant to cash-settled swaps or other derivatives) will be retired and will no longer be
Outstanding under the Indenture. 
 (e) Denominations. Pursuant to Sections 2.01 and 2.02 of the Base Indenture, the
Securities will be issued only in minimum denominations of $1,000 and integral multiples of $1,000 in excess thereof. 
 Section
2.02 Forms. 
 (a) In General. Pursuant to Section 2.02 of the Base Indenture, the Securities will be
substantially in the forms set forth in Exhibit A hereto, and may include such insertions, omissions, substitutions and other variations as are required or permitted by the Indenture, and may have such letters, numbers or other marks of
identification and such legends or endorsements placed thereon as may be required to comply with the rules of any securities exchange or as may, consistently herewith, be determined by the officers executing such Securities, as evidenced by their
execution of the Securities. 
 Notwithstanding Section 2.04 of the Base Indenture, each Security will bear a
Trustee’s certificate of authentication substantially in the form included in Exhibit A hereto. Each Security will also bear a form of notice of conversion, form of fundamental change purchase notice and form of assignment and transfer
substantially in the form set forth in Attachments 1, 2 and 3, respectively, to Exhibit A hereto. 

Notwithstanding Section 2.11 of the Base Indenture, any Security that is a Global Security will bear a legend substantially in the
form of the legend set forth in Section 2.11(a) of the Base Indenture and shall also bear the “Schedule of Increases and Decreases of Global Security” set forth in Annex A to Exhibit A hereto. 

The terms and provisions contained in the Securities will constitute, and are hereby expressly made, a part of this Indenture and, to the
extent applicable, the Company and the Trustee, by their execution and delivery of this Supplemental Indenture, expressly agree to such 

  
 15 

 
terms and provisions and to be bound thereby. However, to the extent that any provision of any Security conflicts with the express provisions of the Indenture, the provisions of this Indenture
will govern and control. 
 (b) Initial and Subsequent Form of Securities. The Company hereby initially appoints The
Depository Trust Company as the Depositary for the Securities, which initially shall be issued in the form of one or more Global Securities without interest coupons (i) registered in the name of Cede & Co., as nominee of the
Depositary, and (ii) delivered to the Trustee as custodian for the Depositary. 
 So long as the Securities are eligible
for book-entry settlement with the Depositary, unless otherwise required by law, and except to the extent provided in Section 2.03(b) hereof, all Securities will be represented by one or more Global Securities. 

(c) Global Securities. Each Global Security will represent the aggregate principal amount of the then Outstanding Securities
endorsed thereon and provide that it represents such aggregate principal amount of the then Outstanding Securities, which aggregate principal amount may, from time to time, be reduced or increased to reflect transfers, exchanges for Securities in
physical form, conversions or repurchases by the Company. 
 Only the Trustee, or the custodian holding such Global Security for
the Depositary, at the direction of the Trustee, may endorse a Global Security to reflect the amount of any increase or decrease in the aggregate principal amount of the then Outstanding Securities represented thereby, and whenever the Holder of a
Global Security delivers instructions to the Trustee to increase or decrease the aggregate principal amount of the then Outstanding Securities represented by a Global Security in accordance with the Indenture and the Applicable Procedures, the
Trustee, or the custodian holding such Global Security for the Depositary, at the direction of the Trustee, will endorse such Global Security to reflect such increase or decrease in the aggregate principal amount of the then Outstanding Securities
represented thereby. None of the Trustee, the Company or any agent of the Trustee or the Company will have any responsibility or bear any liability for any aspect of the records relating to or payments made on account of the ownership of any
beneficial interest in a Global Security or with respect to maintaining, supervising or reviewing any records relating to such beneficial interest. 
 Members of, or participants in, the Depositary (“Agent Members”) shall have no rights under the Indenture with respect to any Global Security held on their behalf by the Depositary, or
the Trustee as its custodian, or under the Global Security, and Cede & Co., or such other Person designated by the Depositary as its nominee, may be treated by the Company, the Trustee and any agent of the Company or the Trustee as the
absolute owner of the Global Security for all purposes whatsoever. Notwithstanding the foregoing, nothing herein shall prevent the Company, the Trustee or any agent of the Company or the Trustee from giving effect to any written certification, proxy
or other authorization furnished by the Depositary or impair, as between the Depositary and its Agent Members, the operation of customary practices governing the exercise of the rights of any Holder. 

Section 2.03 Transfer and Exchange. 

  
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 (a) In General. Notwithstanding anything to the contrary in Section 2.05 of the
Base Indenture, the Company is not required to transfer or exchange any Securities or portions thereof that have been surrendered for purchase in accordance with Article 3 hereof, for conversion in accordance with Article 4 hereof or selected
for redemption in accordance with Article 6 hereof, and a written form of transfer substantially in the form of the Form of Assignment and Transfer set forth in Attachment 3 to Exhibit A hereto will be deemed to be written instrument
of transfer satisfactory to the Company and the Registrar. 
 At such time as all interests in a Global Security have been
repurchased, converted, redeemed, cancelled or exchanged for Securities in certificated form, such Global Security shall, upon receipt thereof, be canceled by the Trustee in accordance with standing procedures and instructions existing between the
Depositary and the custodian for the Global Security. At any time prior to such cancellation, if any interest in a Global Security is repurchased, converted, redeemed, cancelled or exchanged for Securities in certificated form, the principal amount
of such Global Security shall, in accordance with the standing procedures and instructions existing between the Depositary and the custodian for the Global Security, be appropriately reduced, and an endorsement shall be made on such Global Security,
by the Trustee or the custodian for the Global Security, at the direction of the Trustee, to reflect such reduction. 
 (b)
Global Securities. Notwithstanding anything to the contrary in Section 2.11 of the Base Indenture, every transfer and exchange of a beneficial interest in a Global Security will be effected through the Depositary in accordance with the
Applicable Procedures and the provisions of the Indenture, and each Global Security may be transferred only as a whole and only (A) by the Depositary to a nominee of the Depositary, (B) by a nominee of the Depositary to the Depositary or
to another nominee of the Depositary, or (C) by the Depositary or any such nominee to a successor Depositary or a nominee of such successor Depositary. 
 (c) Holders Deemed Owners. Prior to due presentment of a Security for registration of transfer, the Company, the Trustee and any agent of the Company or the Trustee may treat the Person in whose
name such Security is registered as the owner and holder of such Security for the purpose of receiving payment of principal of and any interest on such Security at the Maturity Date, in connection with a Fundamental Change, upon any conversion or
redemption and for all other purposes whatsoever, including delivery of shares of Common Stock on conversion, for distribution of notices to such Holders or solicitations of their consent, whether or not such Security be overdue, and neither the
Company, the Trustee nor any agent of the Company or the Trustee shall be affected by notice to the contrary. 
 Notwithstanding
anything to the contrary in Section 2.11 of the Base Indenture: 
 (1) Each Global Security will be exchanged for Physical
Securities if the Depositary delivers notice to the Company that the Depositary is unwilling, unable or no longer permitted under applicable law to continue to act as Depositary, and the Company fails to appoint a successor Depositary within 90
calendar days after receiving notice from the Depositary. 

  
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 (2) If an Event of Default has occurred and is continuing, any owner of a beneficial
interest in a Global Security may exchange such beneficial interest for Physical Securities by delivering a written request to the Registrar. 
 In the case of an exchange for Physical Securities under clause (1) above: 
 (A) each Global Security will be deemed surrendered to the Trustee for cancellation; 
 (B) the Trustee will cause each Global Security to be cancelled in accordance with the Applicable Procedures; and 
 (C) the Company, in accordance with Section 2.04 of the Base Indenture, will promptly execute, and, upon receipt of a Company Order, the Trustee, in accordance with Section 2.04 of the Base
Indenture, will promptly authenticate and deliver, for each beneficial interest in each Global Security so exchanged, an aggregate principal amount of Physical Securities equal to the aggregate principal amount of such beneficial interest,
registered in such names and in such authorized denominations as the Depositary specifies, and bearing any legends that such Physical Securities are required to bear under this Indenture. 

In the case of an exchange for Physical Securities under clause (2) above: 

(A) the Registrar will deliver notice of such request to the Company and the Trustee, which notice will identify the owner of the
beneficial interest to be exchanged, the aggregate principal amount of such beneficial interest and the CUSIP of the relevant Global Security, in each case if and as such information is provided to the Registrar by the Depositary; 

(B) the Company, in accordance with Section 2.04 of the Base Indenture, will promptly execute, and, upon receipt of a Company
Order, the Trustee, in accordance with Section 2.04 of the Base Indenture, will promptly authenticate and deliver to such owner, for the beneficial interest so exchanged by such owner, Physical Securities registered in such owner’s name
having an aggregate principal amount equal to the aggregate principal amount of such beneficial interest and bearing any legends that such Physical Securities are required to bear under this Indenture; and 

(C) the Registrar, in accordance with the Applicable Procedures, will cause the principal amount of such Global Security to be decreased
by the aggregate principal amount of the beneficial interest so exchanged. If all of the beneficial interests in a Global Security are so exchanged, such Global Security will be deemed surrendered to the Trustee for cancellation, and the Trustee
will cause such Global Security to be cancelled in accordance with the Applicable Procedures. 
 In each of the cases described
in clauses (1) and (2) above, the Company may rely on the Depositary to provide all names of beneficial owners and their respective principal amounts beneficially owned and may issue Physical Securities registered in the names and amounts
so provided by the Depositary. 

  
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 (d) Physical Securities. Except to the extent otherwise provided in
Section 2.03(a) hereof, Physical Securities may be transferred or exchanged in accordance with Section 2.05 of the Base Indenture. 
 Section 2.04 Payments on the Securities. 
 (a) In General.
Each Security will accrue interest at a rate equal to 4.25% per annum from the most recent date to which interest has been paid or duly provided for, or, if no interest has been paid or duly provided for, the Issue Date. Interest on a Security
will cease to accrue upon the earliest of the Maturity Date, subject to the provisions of Article 3 hereof, any Fundamental Change Purchase Date for such Security, subject to the provisions of Article 4 hereof, any Conversion Date for such Security,
and subject to the provisions of Article 6 hereof, any Redemption Date for such Security. Interest on any Security will be payable semi-annually in arrears on each Interest Payment Date, beginning February 15, 2013, to the Holder of such
Security as of the Close of Business on the Regular Record Date immediately preceding the applicable Interest Payment Date. Interest will be computed on the basis of a 360-day year comprised of twelve 30-day months. The Company shall be obligated to
pay Holders Supplementary Interest under the circumstances set forth in Section 9.04 hereof. 
 The Securities will mature
on the Maturity Date, and on the Maturity Date, each Holder of a then Outstanding Security will be entitled on such date to receive $1,000 in cash for each $1,000 in principal amount of then Outstanding Securities held, together with accrued and
unpaid interest to, but not including, the Maturity Date on such then Outstanding Securities. 
 Notwithstanding anything to the
contrary, if the Maturity Date or any Redemption Date or any Interest Payment Date or Fundamental Change Purchase Date or any Conversion Date falls, or if any payment, delivery, notice or other action by the Company is otherwise due, on a day that
is not a Business Day, then any action to be taken on such date need not be taken on such date, but may be taken on the immediately following Business Day with the same force and effect as if taken on such date, and no additional interest will
accrue and no default shall occur on account of such delay. 
 (b) Method of Payment. The Company will pay the principal
of, the Fundamental Change Purchase Price for, the Redemption Price for, and any cash portion of the Settlement Amount with respect to, any Physical Security to the Holder of such Security in cash at the Corporate Trust Office, prior to 10:00 a.m.
on the relevant payment or settlement date, as the case may be. The Company will pay any interest on any Physical Security to the Holder of such Security (i) if such Holder holds $2,000,000 or less aggregate principal amount of Securities, by
check mailed to such Holder’s registered address, and (ii) if such Holder holds more than $2,000,000 aggregate principal amount of Securities, (A) by check mailed to such Holder’s registered address or, (B) if such Holder
delivers to the Trustee and Paying Agent a written request no later than the Regular Record Date for the relevant interest payment that the Company make such payments by wire transfer to an account of such Holder within the United States, for each
interest payment corresponding to each Regular Record Date occurring during the period beginning on the date on which such Holder delivered such request and ending on the date, if any, on which such Holder delivers to the Registrar a written
instruction to the contrary, by wire transfer of immediately available funds to the account specified by such Holder. 

  
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 The Company will pay the principal of, interest on, the Fundamental Change Purchase Price or
Redemption Price for, and any cash portion of the Settlement Amount with respect to, any Global Security to the Depositary by wire transfer of immediately available funds on the relevant payment date in accordance with Applicable Procedures.

 (c) Defaulted Payments. The Company shall pay any interest on the Securities that is payable, but is not punctually
paid or duly provided for, on the applicable Interest Payment Date, in accordance with Section 2.03 of the Base Indenture. 

Section 2.03 of the Base Indenture shall be amended for purposes of the Securities by inserting the words “and
Section 4.01 hereof” immediately following the reference to “Section 2.01(a)(23)” in the third sentence of the first paragraph thereof. 
 The second sentence of the second paragraph of Section 2.03 of the Base Indenture shall not apply to the Securities. 
 ARTICLE 3. 
 FUNDAMENTAL CHANGE AND PURCHASES 

Section 3.01 Purchase at Option of Holders upon a Fundamental Change. (a) If a Fundamental Change occurs at any time, then
each Holder shall have the right, at such Holder’s option, to require the Company to purchase for cash all of such Holder’s Securities, or any portion thereof such that the remaining principal amount of each Security that is not purchased
in full equals $1,000 or an integral multiple of $1,000 in excess thereof, on a date (the “Fundamental Change Purchase Date”) specified by the Company that is not less than 20 calendar days or more than 35 calendar days following
the date on which the Company delivers the Fundamental Change Company Notice, at a purchase price (the “Fundamental Change Purchase Price”) equal to 100% of the principal amount thereof, plus accrued and unpaid interest
thereon, if any, to, but excluding, the Fundamental Change Purchase Date (unless the Fundamental Change Purchase Date is after a Regular Record Date and on or prior to the Interest Payment Date to which such Regular Record Date relates, in which
case the Company will instead pay the full amount of accrued and unpaid interest to the Holder of record on such Regular Record Date and the Fundamental Change Purchase Price will be equal to 100% of the principal amount of the Securities to be
purchased). 
 Purchases of Securities under this Section 3.01 shall be made, at the option of the Holder thereof, upon:

 (1) if the Securities to be purchased are Physical Securities, delivery to the Paying Agent by the Holder of a duly
completed notice (the “Fundamental Change Purchase Notice”) in the form set forth in Attachment 2 to the Form of Security attached hereto as Exhibit A and of the Securities, duly endorsed for transfer, on or
before the Close of Business on the second Business Day immediately preceding the Fundamental Change Purchase Date, subject to extensions to comply with applicable law (the “Fundamental Change Expiration Time”); and 

(2) if the Securities to be purchased are Global Securities, delivery of the Securities, by book-entry transfer, in compliance with the
Applicable Procedures of the 

  
 20 

 
Depositary and the satisfaction of any other requirements of the Depositary in connection with tendering beneficial interests in a Global Security for purchase, by the Fundamental Change
Expiration Time. 
 The Fundamental Change Purchase Notice in respect of any Securities to be purchased shall state: 

(1) if certificated, the certificate numbers of such Securities; 

(2) the portion of the principal amount of such Securities, which must be such that the principal amount that is not to be purchased of
each Security that remains Outstanding in full equals $1,000 or an integral multiple of $1,000 in excess thereof; and 
 (3)
that such Securities are to be purchased by the Company pursuant to the applicable provisions of the Securities and this Indenture. 
 Notwithstanding anything herein to the contrary, any Holder delivering to the Paying Agent the Fundamental Change Purchase Notice contemplated by this Section 3.01 shall have the right to withdraw,
in whole or in part, such Fundamental Change Purchase Notice at any time prior to the Close of Business on the Business Day immediately preceding the Fundamental Change Purchase Date by delivery of a written notice of withdrawal to the Paying Agent
in accordance with Section 3.03. 
 The Paying Agent shall promptly notify the Company of the receipt by it of any
Fundamental Change Purchase Notice or written notice of withdrawal thereof. 
 (b) On or before the 20th calendar day after the
occurrence of a Fundamental Change, the Company shall provide to all Holders of the Securities, the Trustee and the Paying Agent (in the case of any Paying Agent other than the Trustee) a written notice (the “Fundamental Change Company
Notice”) of the occurrence of such Fundamental Change and of the resulting purchase right at the option of the Holders arising as a result thereof. Such notice shall be sent by first class mail or, in the case of any Global Securities, in
accordance with the procedures of the Depositary for providing notices. Simultaneously with providing such Fundamental Change Company Notice, the Company shall publish such information on the Company’s website or through such other public
medium as the Company may use at such time. 
 Each Fundamental Change Company Notice shall specify: 

(1) the events causing the Fundamental Change; 
 (2) the date of the Fundamental Change; 
 (3) the last date on which a Holder of
Securities may exercise the purchase right pursuant to this Article 3; 
 (4) the Fundamental Change Purchase Price;

 (5) the Fundamental Change Purchase Date; 

  
 21 

 (6) the name and address of the Paying Agent and the Conversion Agent, if applicable;

 (7) the applicable Conversion Rate and any adjustments to the applicable Conversion Rate; 

(8) if applicable, that the Securities with respect to which a Fundamental Change Purchase Notice has been delivered by a Holder may be
converted only if the Holder withdraws the Fundamental Change Purchase Notice in accordance with this Indenture; 
 (9) that
the Holder must exercise the purchase right prior to the Fundamental Change Expiration Time; 
 (10) that the Holder shall have
the right to withdraw any Securities surrendered for purchase prior to the Fundamental Change Expiration Time; and 
 (11) the
procedures that Holders must follow to require the Company to purchase their Securities. 
 No failure of the Company to give
the foregoing notices and no defect therein shall limit the purchase rights of the Holders of Securities or affect the validity of the proceedings for the purchase of the Securities pursuant to this Section 3.01. 

(c) Notwithstanding the foregoing, there shall be no purchase of any Securities pursuant to this Section 3.01 if the principal
amount of the Securities has been accelerated, and such acceleration has not been rescinded, on or prior to the Fundamental Change Purchase Date (except in the case of an acceleration resulting from a default by the Company in the payment of the
Fundamental Change Purchase Price with respect to such Securities). The Paying Agent will promptly return to the respective Holders thereof any Physical Securities held by it during the acceleration of the Securities (except in the case of an
acceleration resulting from a default by the Company in the payment of the Fundamental Change Purchase Price with respect to such Securities) and shall deem to be cancelled any instructions for book-entry transfer of the Securities in compliance
with the procedures of the Depositary, in which case, upon such return or cancellation, as the case may be, the Fundamental Change Purchase Notice with respect thereto shall be deemed to have been withdrawn. 

Section 3.02 Effect of Fundamental Change Purchase Notice. Upon receipt by the Paying Agent of a Fundamental Change Purchase
Notice specified in Section 3.01, the Holder of the Security in respect of which such Fundamental Change Purchase Notice was given shall (unless such Fundamental Change Purchase Notice is withdrawn in accordance with Section 3.03)
thereafter be entitled to receive solely the Fundamental Change Purchase Price in cash with respect to such Security. Such Fundamental Change Purchase Price shall be paid to such Holder, subject to receipt of funds by the Paying Agent, on the later
of (x) the applicable Fundamental Change Purchase Date (provided the conditions in Section 3.01 have been satisfied, and subject to extensions to comply with applicable law) and (y) the time of delivery or book-entry transfer
of such Security to the Paying Agent by the Holder thereof in the manner required by Section 3.01. 

  
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 Section 3.03 Withdrawal of Fundamental Change Purchase Notice. A Fundamental Change
Purchase Notice may be withdrawn (in whole or in part) by means of a written notice of withdrawal delivered to the Paying Agent in accordance with the Fundamental Change Company Notice at any time prior to the Close of Business on the Business Day
immediately preceding the Fundamental Change Purchase Date, specifying: 
 (a) the principal amount of the Securities with
respect to which such notice of withdrawal is being submitted; 
 (b) if Physical Securities have been issued, the certificate
numbers of the withdrawn Securities; and 
 (c) the principal amount, if any, of each Security that remains subject to the
Fundamental Change Purchase Notice, which must be such that the principal amount not to be purchased equals $1,000 or an integral multiple of $1,000 in excess thereof; 
 provided, however, that if the Securities are Global Securities, the notice must comply with Applicable Procedures of the Depositary. 

The Paying Agent will promptly return to the respective Holders thereof any Physical Securities with respect to which a Fundamental
Change Purchase Notice has been withdrawn in compliance with the provisions of this Section 3.03. 
 Section 3.04
Deposit of Fundamental Change Purchase Price. On or prior to 11:00 a.m., New York City time, on the Fundamental Change Purchase Date, the Company shall deposit with the Paying Agent (or, if the Company or a Subsidiary or an Affiliate of
either of them is acting as the Paying Agent, shall segregate and hold in trust as provided herein) an amount of money (in immediately available funds if deposited on such Business Day) sufficient to pay the Fundamental Change Purchase Price of all
the Securities or portions thereof that are to be purchased as of the Fundamental Change Purchase Date. If the Paying Agent holds cash sufficient to pay the Fundamental Change Purchase Price of the Securities for which a Fundamental Change Purchase
Notice has been tendered and not withdrawn in accordance with this Indenture on the Fundamental Change Purchase Date, then as of such Fundamental Change Purchase Date, (a) such Securities will cease to be Outstanding and interest will cease to
accrue thereon (whether or not book-entry transfer of such Securities is made or such Securities have been delivered to the Paying Agent) and (b) all other rights of the Holders in respect thereof will terminate (other than the right to receive
the Fundamental Change Purchase Price upon delivery or book-entry transfer of such Securities). 
 Section 3.05 Securities
Purchased in Whole or in Part. Any Security that is to be purchased, whether in whole or in part, shall be surrendered at the office of the Paying Agent (with, if the Company or the Trustee so requires in the case of Physical Securities, due
endorsement by, or a written instrument of transfer in form satisfactory to the Company and the Trustee duly executed by, the Holder thereof or such Holder’s attorney duly authorized in writing) and the Company shall execute and the Trustee
shall authenticate and deliver to the Holder of such Security, without service charge, a new Security or Securities, of any authorized denomination as requested by such Holder in aggregate principal amount equal to, and in

  
 23 

 
exchange for, the portion of the principal amount of the Security so surrendered that is not purchased. 
 Section 3.06 Covenant to Comply with Applicable Laws upon Purchase of Securities. In connection with any offer to purchase Securities under Section 3.01, the Company shall, in each case if
required by law, (i) comply with Rule 13e-4, Rule 14e-1 and any other tender offer rules under the Exchange Act that may then be applicable, (ii) file a Schedule TO or any other required schedule under the Exchange Act and
(iii) otherwise comply with all federal and state securities laws applicable to the Company in connection with such purchase offer. 
 Section 3.07 Repayment to the Company. To the extent that the aggregate amount of cash deposited by the Company pursuant to Section 3.04 exceeds the aggregate Fundamental Change Purchase Price
of the Securities or portions thereof that the Company is obligated to purchase as of the Fundamental Change Purchase Date, then, following the Fundamental Change Purchase Date, the Paying Agent shall promptly return any such excess to the Company.

 ARTICLE 4. 
 CONVERSION 
 Section 4.01 Right To Convert. (a) Subject to and
upon compliance with the provisions of the Indenture, each Holder shall have the right, at such Holder’s option, to convert its Securities, or any portion of its Securities such that the principal amount that remains Outstanding of each
Security that is not converted in full equals $1,000 or an integral multiple of $1,000 in excess thereof, into the Settlement Amount determined in accordance with Section 4.03(a) hereof (the “Conversion Obligation”),
(x) prior to the Close of Business on the Business Day immediately preceding May 15, 2019, only upon satisfaction of one or more of the conditions described in Section 4.01(b) hereof, and (y) on or after May 15, 2019, at any
time prior to the Close of Business on the second Scheduled Trading Day immediately preceding the Maturity Date. 
 (b) (1)
Prior to the Close of Business on the Business Day immediately preceding May 15, 2019, a Holder may surrender Securities for conversion during any fiscal quarter commencing after September 28, 2012 (and only during such fiscal quarter) if
the Last Reported Sale Price of the Common Stock for at least 20 Trading Days (whether or not consecutive) during the period of 30 consecutive Trading Days ending on the last Trading Day of the immediately preceding fiscal quarter is greater than or
equal to 130% of the Conversion Price in effect on each applicable Trading Day. 
 (2) Prior to the Close of Business on the
Business Day immediately preceding May 15, 2019, a Holder may surrender all or a portion of its Securities for conversion during the five Business Day period after any five consecutive Trading Day period (the “Measurement
Period”) in which the Trading Price per $1,000 principal amount of Securities, as determined following a request by a Holder in accordance with the procedures set forth in this Section 4.01(b)(2), for each Trading Day of such
Measurement Period was less than 98% of the product of (i) the Conversion Rate in effect on such Trading Day and (ii) the Last Reported Sale Price of the Common Stock on such Trading Day. The Company shall provide written notice to the Bid
Solicitation Agent (if other than the Company) of the three independent nationally 

  
 24 

 
recognized securities dealers selected by the Company in accordance with the definition of Trading Price, along with the appropriate contact information for each. The Bid Solicitation Agent (if
other than the Company) shall have no obligation to solicit secondary market bid quotations for the Securities unless the Company has requested it to do so; and the Company shall have no obligation to make such request (or, if the Company is acting
as Bid Solicitation Agent, to determine the Trading Price of the Securities) unless a Holder of a Security provides it with reasonable evidence that the Trading Price per $1,000 principal amount of Securities would be less than 98% of the product of
(i) the Conversion Rate in effect on the next Trading Day and (ii) the Last Reported Sale Price of the Common Stock on such Trading Day. Notwithstanding the definition of “Trading Price,” if (i) the Company does not so
instruct the Bid Solicitation Agent to obtain bids when required, or the Bid Solicitation Agent fails to solicit bids when required, (ii) the Company is acting as Bid Solicitation Agent and fails to obtain bids when so required or
(iii) the Trading Price is otherwise not determined as required, the Trading Price per $1,000 principal amount of the Securities will be deemed to be less than 98% of the product of (i) the Conversion Rate and (ii) the Trading Price
for each Trading Day on which the Company or the Bid Solicitation Agent fails to do so, as the case may be. At such time, the Company shall, or shall instruct the Bid Solicitation Agent to (if other than the Company) determine the Trading Price per
$1,000 principal amount of the Securities beginning on the next Trading Day and on each successive Trading Day until the Trading Price per $1,000 principal amount of Securities for a Trading Day is greater than or equal to 98% of the product of
(i) the Conversion Rate in effect on such Trading Day and (ii) the Last Reported Sale Price of the Common Stock on such Trading Day. Whenever the condition to conversion set forth in this Section 4.01(b)(2) has been met, but was not
met on the immediately preceding Trading Day, the Company will so notify the Holders, the Trustee and the Conversion Agent (if other than the Trustee) in writing. If, at any time after the condition to conversion set forth in this
Section 4.01(b)(2) has been met, the condition to conversion set forth in this Section 4.01(b)(2) ceases to be met, the Company will so notify the Holders, the Trustee and the Conversion Agent (if other than the Trustee) in writing.

 (3) If the Company calls the Securities for redemption prior to the Close of Business on the Business Day immediately
preceding May 15, 2019 pursuant to Article 6 hereof, Holders may convert their notes at any time prior to the Close of Business on the second Scheduled Trading Day prior to the Redemption Date, even if the Securities are not otherwise
convertible at such time, after which time the Holder’s right to convert the Securities will expire (unless the Company defaults in the payment of the Redemption Price, in which case a Holder of the Securities may convert such Securities until
the Redemption Price has been paid or duly provided for). 
 (4) If the Company elects to (x) issue to all or
substantially all holders of the Common Stock rights, options or warrants entitling them for a period of not more than 50 calendar days after the date of such issuance to subscribe for or purchase shares of the Common Stock, at a price per share
less than the average of the Last Reported Sale Prices of the Common Stock for the 10 consecutive Trading Day period ending on the Trading Day immediately preceding the date of announcement of such issuance; or (y) distribute to all or
substantially all holders of the Common Stock the Company’s assets, debt securities or rights to purchase the Company’s securities, which distribution has a per-share value, as reasonably determined by the Board of Directors, exceeding 10%
of the Last Reported Sale Price of the Common Stock on the Trading Day preceding the date of announcement for such distribution, then, the Company must 

  
 25 

 
deliver notice of such issuance or distribution, and of the Ex-Dividend Date for such issuance or distribution, to the Holders at least 55 Scheduled Trading Days prior to the Ex-Dividend Date for
such issuance or distribution. Holders may surrender their Securities for conversion at any time during the period beginning on the 55th Scheduled Trading Day immediately prior to the Ex-Dividend Date for such issuance or distribution and ending on
the earlier of (a) the Close of Business on the Business Day immediately preceding the Ex-Dividend Date for such issuance or distribution or (b) its announcement that such issuance or distribution will not take place, even if the
Securities are not otherwise convertible at such time; provided, however, that Holders may not convert any of their Securities pursuant to this Section 4.01(b)(4) if the Company provides that Holders shall participate, at the same
time and upon the same terms as holders of the Common Stock, and as a result of holding the Securities, in the relevant issuance or distribution without having to convert their Securities as if they held a number of shares of the Common Stock equal
to the Conversion Rate in effect on the Ex-Dividend Date for such issuance or distribution multiplied by the principal amount (expressed in thousands) of Securities held by such Holder on the Ex-Dividend Date for such issuance or distribution.

 (5) If (i) a Make-Whole Fundamental Change occurs or (ii) the Company is a party to (a) a consolidation,
merger or binding share exchange, pursuant to which the Common Stock would be converted into cash, securities or other assets or (b) a sale, conveyance, transfer or lease of all or substantially all of the assets of the Company, the Securities
may be surrendered for conversion at any time from or after the date that is 20 Scheduled Trading Days prior to the anticipated effective date of such transaction (or, if later, the Business Day after the Company gives notice of such transaction)
until the Close of Business (i) if such transaction or event is a Fundamental Change, on the Business Day immediately preceding the Fundamental Change Purchase Date, and (ii) otherwise, on the 35th Business Day immediately following the
effective date for such transaction or event. The Company will notify the Trustee and Holders of any such transaction: 
 (A) as promptly as practicable following the date the Company publicly announces such transaction but in no event less than 20 Scheduled Trading Days prior to the anticipated effective date of such
transaction; or 
 (B) if the Company does not have knowledge of such transaction at least 20 Scheduled Trading
Days prior to the anticipated effective date of such transaction, within two Business Days of the date upon which the Company receives notice, or otherwise becomes aware, of such transaction, but in no event later than the actual effective date of
such transaction. 
 Section 4.02 Conversion Procedures. 

(a) Each Security shall be convertible at the office of the Conversion Agent and, if applicable, in accordance with the Applicable
Procedures of the Depositary. 
 (b) To exercise the conversion privilege with respect to a beneficial interest in a Global
Security, the Holder must complete the appropriate instruction form for conversion pursuant to the Depositary’s book-entry conversion program, furnish appropriate endorsements and transfer documents if required by the Company or the Conversion
Agent, and pay the funds, 

  
 26 

 
if any, required by Section 4.02(f) and any taxes or duties if required pursuant to Section 4.02(g), and the Conversion Agent must be informed of the conversion in accordance with the
customary practice of the Depositary. 
 To exercise the conversion privilege with respect to any Physical Securities, the
Holder of such Physical Securities shall: 
 (1) complete and manually sign a conversion notice in the form set forth in the
Form of Notice of Conversion (the “Conversion Notice”) or a facsimile of the Conversion Notice; 
 (2) deliver
the Conversion Notice, which is irrevocable, and the Security to the Conversion Agent; 
 (3) if required, furnish appropriate
endorsements and transfer documents; 
 (4) if required, make any payment required under Section 4.02(f); and 

(5) if required, pay all transfer or similar taxes as set forth in Section 4.02(g). 

If, upon conversion of a Security, any shares of Common Stock are to be issued to a Person other than the Holder of such Security, the related Conversion
Notice shall include such other Person’s name and address. 
 If a Holder has already delivered a Fundamental Change
Purchase Notice as described in Section 3.01 with respect to a Security, the Holder may not surrender that Security for conversion until the Holder has withdrawn such notice in accordance with Section 3.03 hereof, except to the extent that
a portion of the Holder’s Security is not subject to a Fundamental Change Purchase Notice. 
 For any Security, the first
Business Day on which the Holder of such Security satisfies all of the applicable requirements set forth above with respect to such Security and on which conversion of such Security is not otherwise prohibited under this Indenture shall be the
“Conversion Date” with respect to such Security. 
 Each conversion shall be deemed to have been effected as to
any such Securities (or portion thereof) surrendered for conversion at the Close of Business on the applicable Conversion Date; provided, however, that, other than as set forth under Section 4.04 hereof, the Person in whose name
the certificate for any shares of Common Stock delivered upon conversion is registered shall be treated as a stockholder of record as of the Close of Business on the Conversion Date (in the case of Physical Settlement) or the last VWAP Trading Day
of the applicable Cash Settlement Averaging Period (in the case of Combination Settlement). At the Close of Business on the Conversion Date for a Security, the converting Holder shall no longer be the Holder of such Security. 

  
 27 

 (c) Endorsement. Any Securities surrendered for conversion shall, unless shares of
Common Stock issuable on conversion are to be issued in the same name as the registration of such Securities, be duly endorsed by, or be accompanied by instruments of transfer in form satisfactory to the Company duly executed by, the Holder or its
duly authorized attorney. 
 (d) Physical Securities. If any Securities in a denomination greater than $1,000 shall be
surrendered for partial conversion, the Company shall execute and the Trustee shall authenticate and deliver to the Holder of the Securities so surrendered, without charge, new Securities in authorized denominations in an aggregate principal amount
equal to the unconverted portion of the surrendered Securities. 
 (e) Global Securities. Upon the conversion of a
beneficial interest in Global Securities, the Conversion Agent shall make a notation in its records as to the reduction in the principal amount represented thereby. The Company shall notify the Trustee in writing of any conversions of Securities
effected through any Conversion Agent other than the Trustee. 
 (f) Interest Due upon Conversion. If a Holder converts a
Security after the Close of Business on a Regular Record Date but prior to the Open of Business on the Interest Payment Date corresponding to such Regular Record Date, such Holder must accompany such Security with an amount of cash equal to the
amount of interest that will be payable on such Security on the corresponding Interest Payment Date; provided, however, that a Holder need not make such payment (1) if the Conversion Date follows the Regular Record Date
immediately preceding the Maturity Date; (2) if the Company has specified a Redemption Date that is after a Regular Record Date and on or prior to the Business Day immediately following the corresponding Interest Payment Date; (3) if the
Company has specified a Fundamental Change Purchase Date that is after a Regular Record Date and on or prior to the Business Day immediately following the corresponding Interest Payment Date; or (4) to the extent of any overdue interest, if any
overdue interest exists at the time of conversion with respect to such Security. 
 (g) Taxes Due upon Conversion. If a
Holder converts a Security, the Company will pay any documentary, stamp or similar issue or transfer tax due on the issue of any shares of the Common Stock upon the conversion, unless the tax is due because the Holder requests that any shares be
issued in a name other than the Holder’s name, in which case the Holder will pay that tax. 
 Section 4.03 Settlement
upon Conversion. 
 (a) Settlement. (1) Subject to this Section 4.03 and Sections 4.06 and 4.07 hereof,
upon conversion of any Security, the Company may make an election with respect to the Settlement Method (a “Settlement Election”) and the Specified Dollar Amount, if applicable (a “Specified Dollar Amount
Election”), it chooses to deliver to Holders in full satisfaction of its Conversion Obligation in respect of each $1,000 principal amount of Securities being converted: cash (“Cash Settlement”), shares of Common Stock
(“Physical Settlement”) or a combination of cash and shares of Common Stock, together with cash, if applicable, in lieu of any fractional share of Common Stock in accordance with Section 4.03(b) (“Combination
Settlement”). 

  
 28 

 (2) Settlement Election. All conversions occurring (x) on or after May 15,
2019 or (y) after the issuance by the Company of a Redemption Notice and prior to the Close of Business on the second Scheduled Trading Day immediately preceding the related Redemption Date shall be settled using the same Settlement Method.
Except for any conversions occurring on or after May 15, 2019 and any conversions that occur after the Company’s issuance of a Redemption Notice, but prior to the Close of Business on the second Scheduled Trading Day preceding the related
Redemption Date, the Company will use the same Settlement Method for all conversions occurring on the same Conversion Date. Except as set forth herein, the Company shall not have any obligation to use the same Settlement Method with respect to
conversions that occur on different Conversion Dates. 
 If the Company elects a Settlement Method, the Company shall inform
Holders so converting, through the Trustee, of the Settlement Method it has selected (the “Settlement Election Notice”), no later than the Close of Business on the Trading Day immediately following the related Conversion Date (or in
the case of any conversion occurring (i) after the date of issuance of a Redemption Notice and prior to the second Scheduled Trading Day preceding the related Redemption Date, in such Redemption Notice, or (ii) on or after May 15,
2019, no later than May 29, 2019 (which is the 55th Scheduled Trading Day preceding the Maturity Date). If the Company does not timely elect a Settlement Method, the Company will no longer have the right to elect Cash Settlement or Physical
Settlement and the Company shall be deemed to have elected Combination Settlement in respect of its conversion obligations, and the Specified Dollar Amount of the Securities shall be deemed equal to $1,000. If the Company elects Combination
Settlement but does not timely notify the converting Holders of the Specified Dollar Amount, such Specified Dollar Amount shall be deemed to be $1,000. 
 Prior to May 29, 2019, which is the 55th Scheduled Trading Day preceding the Maturity Date, the Company shall have the right to irrevocably elect Combination Settlement with a Specified Dollar Amount
of $1,000 by delivering a written notice to all Holders of the Securities, the Trustee and the Conversion Agent and issuing a press release containing the relevant information and make such information available on the Company’s website.
Following such irrevocable election, the Company shall not have the right to change the Settlement Method. 
 (3) Settlement
Amount. The cash, shares of Common Stock or combination of cash and shares of Common Stock in respect of any conversion of Securities (the “Settlement Amount”) shall be computed as follows: 

(A) if the Company elects Physical Settlement, the Company shall deliver to the converting Holder a number of shares of Common Stock
equal to the product of (i) the aggregate principal amount of Securities to be converted, divided by $1,000 and (ii) the applicable Conversion Rate; 
 (B) if the Company elects Cash Settlement, the Company shall deliver to the converting Holder, in respect of each $1,000 principal amount of Securities being converted, cash in an amount equal to the sum
of the Daily Conversion Values for each of the 50 consecutive VWAP Trading Days during the related Cash Settlement Averaging Period; and 

  
 29 

 (C) if the Company elects Combination Settlement, the Company shall deliver to the
converting Holder, in respect of each $1,000 principal amount of Securities being converted, an amount of cash and shares of Common Stock equal to the sum of the Daily Settlement Amounts for each of the 50 consecutive VWAP Trading Days during the
applicable Cash Settlement Averaging Period. 
 (4) Delivery Obligation. The Company shall pay or deliver, as the case
may be, the consideration due in respect of its Conversion Obligation (i) no later than the third Business Day immediately following the applicable Conversion Date, if the Company elects to satisfy its Conversion Obligation in respect of such
conversion by Physical Settlement; provided that for all such conversions occurring on or after the 55th Scheduled Trading Day immediately preceding the Maturity Date, the Company shall deliver the shares of Common Stock on the Maturity Date;
and (ii) except to the extent otherwise provided pursuant to Section 4.06 hereof, no later than the third Business Day immediately following the last VWAP Trading Day of the applicable Cash Settlement Averaging Period, if the Company
elects to satisfy its Conversion Obligation in respect of such conversion by Cash Settlement or Combination Settlement. In either case, delivery on such third Business Day shall be deemed timely and shall not result in any Default hereunder even if
such Business Day occurs after the Maturity Date. 
 (b) Fractional Shares. Notwithstanding the foregoing, the Company
will not issue fractional shares of Common Stock as part of the Settlement Amount due with respect to any converted Security. Instead, if any Settlement Amount includes a fraction of a share of the Common Stock, the Company will, in lieu of
delivering such fraction of a share of Common Stock, pay an amount of cash (i) in the case Physical Settlement applies to the Conversion Obligation, based on the Daily VWAP of the Common Stock on the relevant Conversion Date, or if such
Conversion Date is not a Trading Day, the immediately preceding Trading Day or (ii) in the case Cash Settlement or Combination Settlement applies to the Conversion Obligation, based on the Daily VWAP on the last Trading Day of the relevant Cash
Settlement Averaging Period (subject to subsection (c) below). 
 (c) Conversion of Multiple Securities by a Single
Holder. If a Holder surrenders more than one Security for conversion on a single Conversion Date, the Company will calculate the amount of cash and the number of shares of Common Stock due with respect to such Securities as if such Holder had
surrendered for conversion one Security having an aggregate principal amount equal to the sum of the principal amounts of each of the Securities surrendered for conversion by such Holder on such Conversion Date. 

(d) Settlement of Accrued Interest and Deemed Payment of Principal. If a Holder converts a Security, the Company will not adjust
the Conversion Rate to account for any accrued and unpaid interest on such Security and the Company’s delivery of cash, shares of Common Stock or a combination of cash and shares of Common Stock into which a Security is convertible will be
deemed to satisfy and discharge in full the Company’s obligation to pay the principal of, and accrued and unpaid interest, if any, on, such Security to, but excluding, the Conversion Date; provided, however, that, subject to
Section 4.02(f), if a Holder converts a Security after a Regular Record Date and prior to the Open of Business on the corresponding Interest Payment Date, the Company will still be obligated to pay the interest due on such Interest Payment Date
to the Holder of such Security on such Regular Record Date. 

  
 30 

 As a result, except as otherwise provided in the proviso to the immediately preceding
sentence, any accrued and unpaid interest with respect to a converted Security will be deemed to be paid in full rather than cancelled, extinguished or forfeited. In addition, if the Settlement Amount for any Security includes both cash and shares
of the Common Stock, accrued and unpaid interest will be deemed to be paid first out of the amount of cash delivered upon such conversion. In no event will a Holder be entitled to receive any dividend or other distribution with respect to any Common
Stock issued on conversion of such Holder’s Securities if the applicable Conversion Date is after the Regular Record Date for such dividend or distribution. Prior to the settlement of any conversion in accordance with Section 4.03, a
Holder shall not be the owner of any Common Stock issuable upon conversion of such Holder’s Securities. 
 (e)
Notices. Whenever a Conversion Date occurs with respect to a Security, the Conversion Agent will, as promptly as possible, and in no event later than the Business Day immediately following such Conversion Date, deliver to the Company and the
Trustee, if it is not then the Conversion Agent, notice that a Conversion Date has occurred, which notice will state such Conversion Date, the principal amount of Securities converted on such Conversion Date and the names of the Holders that
converted Securities on such Conversion Date. 
 On the first Business Day immediately following the last VWAP Trading Day of
the Cash Settlement Averaging Period applicable to any converted Security to which Cash Settlement or Combination Settlement is applicable, the Company will deliver written notice to the Conversion Agent and the Trustee stating the amount of cash
and the number of shares of Common Stock, if any, that the Company is obligated to pay to satisfy its conversion obligation with respect to each Security converted on such Conversion Date. 

Section 4.04 Adjustment of Conversion Rate. The Conversion Rate will be adjusted as described in this Section 4.04, except
that the Company shall not make any adjustment to the Conversion Rate if Holders participate (other than in the case of a share split or share combination), at the same time and upon the same terms as holders of the Common Stock and as a result of
holding the Securities, in any of the transactions described below without having to convert their Securities, as if they held a number of shares of Common Stock equal to the applicable Conversion Rate, in respect of each $1,000 principal amount of
Securities. 
 (a) If the Company exclusively issues shares of Common Stock as a dividend or distribution on all or
substantially all shares of the Common Stock, or if the Company effects a share split or share combination, the Conversion Rate will be adjusted based on the following formula: 

 
 

 
 where 
  

					
	CR0    	 	=	 	the Conversion Rate in effect immediately prior to the Open of Business on the Ex-Dividend Date of such dividend or distribution, or immediately prior to the Open of Business on
the effective date of such share split or combination, as applicable;

  
 31 

							
	CR1	  	 	=	  	  	the Conversion Rate in effect immediately after the Open of Business on such Ex-Dividend Date or such effective date;
			
	OS0	  	 	=	  	  	the number of shares of Common Stock outstanding immediately prior to the Open of Business on such Ex-Dividend Date or such effective date; and
			
	OS1	  	 	=	  	  	the number of shares of Common Stock outstanding immediately after giving effect to such dividend, distribution, share split or share combination.

 Any adjustment made under this Section 4.04(a) shall become effective immediately after the Open of
Business on the Ex-Dividend Date for such dividend or distribution, or immediately after the Open of Business on the effective date for such share split or share combination. If any dividend or distribution of the type described in this
Section 4.04(a) is declared but not so paid or made, the Conversion Rate shall be immediately readjusted, effective as of the date the Board of Directors determines not to pay such dividend or distribution to the Conversion Date that would then
be in effect if such dividend or distribution had not been declared. 
 (b) If the Company issues to all or substantially all
holders of the Common Stock any rights, options or warrants entitling them, for a period of not more than 50 calendar days after the date of such issuance, to subscribe for or purchase shares of the Common Stock, at a price per share less than the
average of the Last Reported Sale Prices of the Common Stock for the 10 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the date of announcement of such issuance, the Conversion Rate will be
increased based on the following formula: 
  
 

 
 where, 
  

							
	CR0	  	 	=	  	  	the Conversion Rate in effect immediately prior to the Open of Business on the Ex-Dividend Date for such issuance;
			
	CR1	  	 	=	  	  	the Conversion Rate in effect immediately after the Open of Business on such Ex-Dividend Date;
			
	OS0	  	 	=	  	  	the number of shares of Common Stock outstanding immediately prior to the Open of Business on such Ex-Dividend Date;
			
	X	  	 	=	  	  	the total number of shares of Common Stock issuable pursuant to such rights, options or warrants; and
			
	Y	  	 	=	  	  	the number of shares of Common Stock equal to the aggregate price payable to exercise such rights, options or warrants divided by the average of the Last Reported Sale
Prices of the Common Stock over the 10 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the date of announcement of the issuance of such rights, options or warrants.

  
 32 

 Any increase made under this Section 4.04(b) will be made successively whenever any
such rights, options or warrants are issued and shall become effective immediately after the Open of Business on the Ex-Dividend Date for such issuance. To the extent that such rights, options or warrants are not exercised prior to their expiration
or shares of Common Stock are not delivered upon the expiration of such rights, options or warrants, the Conversion Rate shall be readjusted to the Conversion Rate that would then be in effect had the increase with respect to the issuance of such
rights, options or warrants been made on the basis of delivery of only the number of shares of Common Stock actually delivered. If such rights, options or warrants are not so issued, or if such rights, options or warrants are not exercised prior to
their expiration, the Conversion Rate shall be decreased to be the Conversion Rate that would then be in effect if such Ex-Dividend Date for such issuance had not occurred. 
 For purposes of this Section 4.04(b) and Section 4.01(b)(4) hereof, in determining whether any rights, options or warrants entitle the holders of the Common Stock to subscribe for or purchase
shares of the Common Stock at a price per share less than such average of the Last Reported Sale Prices of the Common Stock for the 10 consecutive Trading Day period ending on the Trading Day immediately preceding the date of announcement for such
issuance, and in determining the aggregate offering price of such shares of the Common Stock, there shall be taken into account any consideration received by the Company for such rights, options or warrants and any amount payable on exercise or
conversion thereof, the value of such consideration, if other than cash, to be determined by the Board of Directors. 
 (c) If
the Company distributes shares of its Capital Stock, evidences of its indebtedness, other assets or property of the Company or rights, options or warrants to acquire its Capital Stock or other securities, to all or substantially all holders of the
Common Stock, excluding: 
 (1) dividends or distributions (including share splits), rights, options or warrants as to which an
adjustment was effected pursuant to Section 4.04(a) hereof or Section 4.04(b) hereof; 
 (2) dividends or
distributions paid exclusively in cash as to which an adjustment was effected pursuant to Section 4.04(d) hereof; 
 (3)
except as otherwise described below pursuant to which an adjustment is made to the Conversion Rate pursuant to this Section 4.04(c), rights issued pursuant to any stockholders rights plan of the Company then in effect; provided that such
rights plan provides for the issuance of such rights with respect to the Common Stock issued upon conversion of the Securities; and 
 (4) Spin-Offs as to which the provisions set forth below in this Section 4.04(c) shall apply; 

(any of such shares of Capital Stock, evidences of indebtedness, other assets or property or rights, options or warrants to acquire Capital Stock or
other securities of the Company, the “Distributed Property”), then the Conversion Rate shall be increased based on the following formula: 

  
 33 

  
 

 
 where 
  

					
	CR0	  	=	  	the Conversion Rate in effect immediately prior to the Open of Business on the Ex-Dividend Date for such distribution;
			
	CR1	  	=	  	the Conversion Rate in effect immediately after the Open of Business on such Ex-Dividend Date;
			
	SP0	  	=	  	the average of the Last Reported Sale Prices of the Common Stock over the 5 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the Ex-Dividend Date for
such distribution; and
			
	FMV	  	=	  	the fair market value (as determined by the Board of Directors) of the shares of Capital Stock, evidences the Company’s indebtedness, other assets, or property of the
Company or rights, options or warrants to acquire the Company’s Capital Stock or other securities distributed with respect to each outstanding share of the Common Stock on the Ex-Dividend Date for such distribution.

 If “FMV” (as defined above) is equal to or greater than the “SP0” (as defined above), in lieu of the foregoing increase, each Holder
of Securities shall receive, in respect of each $1,000 principal amount of Securities it holds, at the same time and upon the same terms as holders of the Common Stock, the amount and kind of Capital Stock, evidences of the Company’s
indebtedness, other assets or property of the Company or rights, options or warrants to acquire the Capital Stock or other securities that such Holder would have received as if such Holder owned a number of shares of Common Stock equal to the
Conversion Rate in effect on the Ex-Dividend Date for the distribution. 
 Any increase made under the portion of this
Section 4.04(c) will become effective immediately after the Open of Business on the Ex-Dividend Date for such distribution. If such distribution is not so paid or made, the Conversion Rate shall be decreased to be the Conversion Rate that would
then be in effect if such dividend or distribution had not been declared. 
 With respect to an adjustment pursuant to this
Section 4.04(c) where there has been a payment of a dividend or other distribution on the Common Stock of shares of Capital Stock of any class or series, or similar equity interest, of or relating to a Subsidiary of the Company or other
business unit of the Company, and such Capital Stock or similar equity interest is listed or quoted (or will be listed or quoted upon the consummation of the distribution) on a United States national securities exchange or a reasonably comparable
non-U.S. equivalent (a “Spin-Off”), the Conversion Rate will be increased based on the following formula: 
  

 

  
 34 

 where, 
  

					
	CR0	  	=	  	the Conversion Rate in effect immediately prior to the Open of Business on the Ex-Dividend Date for such Spin-Off;
			
	CR1	  	=	  	the Conversion Rate in effect immediately after the Open of Business on the Ex-Dividend Date for such Spin-Off;
			
	FMV0	  	=	  	the average of the Last Reported Sale Prices of the Capital Stock or similar equity interest distributed to holders of Common Stock applicable to one share of Common Stock
(determined by reference to the definition of Last Reported Sale Price as if reference therein to Common Stock were to such Capital Stock or similar equity interest) over the first 10 consecutive Trading Day period after, and including, the
Ex-Dividend Date of the Spin-Off (the “Valuation Period”); and
			
	MP0	  	=	  	the average of the Last Reported Sale Prices of Common Stock over the Valuation Period.

 For purposes of the second adjustment set forth in this Section 4.04(c), the adjustment to such
Conversion Rate shall be determined immediately after the Close of Business on the last day of the Valuation Period but shall be given effect immediately after the Open of Business on the Ex-Dividend Date for the Spin-Off. If the Ex-Dividend Date
for the Spin-Off is less than 10 Trading Days prior to, and including, the end of the Cash Settlement Averaging Period in respect of any conversion, references within this Section 4.04(c) to 10 Trading Days shall be deemed to be replaced solely
in respect of that conversion, with such lesser number of Trading Days as have elapsed from, and including, the Ex-Dividend Date for the Spin-Off to, and including, the last Trading Day of such Cash Settlement Averaging Period. In respect of any
conversion during the Valuation Period for any Spin-Off, references within this Section 4.04(c) related to 10 Trading Days shall be deemed to be replaced with such lesser number of Trading Days as have elapsed from, and including, the
Ex-Dividend Date for such Spin-Off to, but excluding, the relevant Conversion Date. If any dividend or distribution that constitutes a Spin-Off is not so paid, the Conversion Rate shall be decreased, effective as of the date the Board of Directors,
determines not to pay such dividends or distributions, to the Conversion Rate that would then be in effect if such dividend or distribution had not been declared. 
 For purposes of Section 4.04(a) hereof, Section 4.04(b) hereof and this Section 4.04(c), if any dividend or distribution to which this Section 4.04(c) applies includes one or both of:

 (A) a dividend or distribution of shares of Common Stock to which Section 4.04(a) hereof also applies
(the “Clause A Distribution”); or 
 (B) a dividend or distribution of rights, options or
warrants to which Section 4.04(b) hereof also applies (the “Clause B Distribution”), 
 then (i) such
dividend or distribution, other than the Clause A Distribution and the Clause B Distribution, shall be deemed to be a dividend or distribution to which this Section 4.04(c) applies (the “Clause C Distribution”) and any
Conversion Rate adjustment required to be made 

  
 35 

 
under this Section 4.04(c) with respect to such Clause C Distribution shall be made, (ii) the Clause B Distribution, if any, shall be deemed to immediately follow the Clause C
Distribution and any Conversion Rate adjustment required by Section 4.04(b) hereof with respect thereto shall then be made, except that, if determined by the Company, (A) the “Ex-Dividend Date” of the Clause B Distribution and
the Clause A Distribution, if any, shall be deemed to be the Ex-Dividend Date of the Clause C Distribution and (B) any shares of Common Stock included in the Clause A Distribution or the Clause B Distribution shall not be deemed to be
“outstanding immediately prior to the Open of Business on such Ex-Dividend Date” within the meaning of Section 4.04(b) hereof, and (iii) the Clause A Distribution, if any, shall be deemed to immediately follow the Clause C
Distribution or the Clause B Distribution, as the case may be, except that, if determined by the Company, (A) the “Ex-Dividend Date” of the Clause A Distribution and the Clause B Distribution, if any, shall be deemed to be the
Ex-Dividend Date of the Clause C Distribution, and (B) any shares of Common Stock included in the Clause A Distribution shall not be deemed to be “outstanding immediately prior to the Open of Business on such Ex-Dividend Date or such
effective date” within the meaning of Section 4.04(a) hereof. 
 (d) If any cash dividend or distribution is made to
all or substantially all holders of the Common Stock, the Conversion Rate shall be adjusted based on the following formula: 
  

 
 where, 
  

					
	CR0	  	=	  	the Conversion Rate in effect immediately prior to the Open of Business on the Ex-Dividend Date for such dividend or distribution;
			
	CR1	  	=	  	the Conversion Rate in effect immediately after the Open of Business on the Ex-Dividend Date for such dividend or distribution;
			
	SP0	  	=	  	the Last Reported Sale Price of the Common Stock on the Trading Day immediately preceding the Ex-Dividend Date for such dividend or distribution; and
			
	C	  	=	  	the amount in cash per share that the Company distributes to holders of the Common Stock.

 If “C” (as defined above) is equal to or greater than “SP0” (as defined above), in lieu of the foregoing increase, each Holder
shall receive, for each $1,000 principal amount of Securities it holds, at the same time and upon the same terms as holders of shares of the Common Stock, the amount of cash that such Holder would have received if such Holder had owned a number of
shares of Common Stock equal to the Conversion Rate on the Ex-Dividend Date for such cash dividend or distribution. Such increase shall become effective immediately after the Open of Business on the Ex-Dividend Date for such dividend or
distribution. If such dividend or distribution is not so paid, the Conversion Rate shall be decreased effective as of the date the Board of Directors of the Company, or a committee thereof, determines not to pay such

  
 36 

 
dividends or distributions, to the Conversion Rate that would then be in effect if such dividend or distribution had not been declared. 

(e) If the Company or any of its Subsidiaries make a payment in respect of a tender offer or exchange offer for the Common Stock, to the
extent that the cash and value of any other consideration included in the payment per share of the Common Stock exceeds the Last Reported Sale Price of the Common Stock on the Trading Day next succeeding the last date on which tenders or exchanges
may be made pursuant to such tender or exchange offer (the “Offer Expiration Date”), the Conversion Rate shall be increased based on the following formula: 

 
 

 
 where, 
  

					
	CR0	 	=	 	the Conversion Rate in effect immediately prior to the Close of Business on the Trading Day next succeeding the Offer Expiration Date;
			
	CR1	 	=	 	the Conversion Rate in effect immediately after the Close of Business on the Trading Day next succeeding the Offer Expiration Date;
			
	AC	 	=	 	the aggregate value of all cash and any other consideration (as determined by the Board of Directors) paid or payable for shares of Common Stock purchased in such tender offer or
exchange offer;
			
	OS0	 	=	 	the number of shares of Common Stock outstanding immediately prior to the expiration time of the tender or exchange offer on the Offer Expiration Date (prior to giving effect to the
purchase of all shares accepted for purchase or exchange in such tender offer or exchange offer);
			
	OS1	 	=	 	the number of shares of Common Stock outstanding immediately after the expiration time of the tender or exchange offer on the Offer Expiration Date (after giving effect to the
purchase of all shares accepted for purchase or exchange in such tender or exchange offer); and
			
	SP1	 	=	 	the average of the Last Reported Sale Prices of the Common Stock over the 10 consecutive Trading Day period commencing on, and including, the Trading Day next succeeding the
Offer Expiration Date (the “Averaging Period”).

 The adjustment to the Conversion Rate in this Section 4.04(e) shall be determined at the Close of
Business on the last day of the Averaging Period but shall be given effect at the Open of Business on the Trading Day next succeeding the Offer Expiration Date. If the Trading Day next succeeding the Offer Expiration Date is less than 10 Trading
Days prior to, and including, the end of the Cash Settlement Averaging Period in respect of any conversion, references in this Section 4.04(e) to 10 Trading Days shall be deemed to be replaced, solely in respect of that conversion, with such
lesser number of Trading Days as have elapsed from, and including, the Trading Day next succeeding the Offer Expiration Date to, and including, the last Trading Day of such Cash Settlement Averaging Period. In respect of any conversion during the 10
Trading 

  
 37 

 
Days commencing on the Trading Day next succeeding the Offer Expiration Date, references in this Section 4.04(e) to 10 Trading Days shall be deemed to be replaced with such lesser number of
Trading Days as have elapsed from, and including, the trading day next succeeding the expiration date to, but excluding, the relevant conversion date. 
 If a Holder converts a Security, when Physical Settlement is applicable to such Security and any Conversion Rate adjustment described herein has become effective on or prior to the applicable
Conversion Date, but the Holder will be entitled to participate in the event giving rise to such adjustment on account of the shares of Common Stock it receives upon conversion of such Security, then, notwithstanding anything to the contrary herein,
the Company shall calculate its conversion obligation to such Holder as if such Conversion Rate adjustment had not been required hereunder and treat such Holder as entitled to participate in such event on account of the shares of Common Stock it
receives upon conversion of such Security. 
 (f) Special Settlement Provisions. Notwithstanding anything to the
contrary herein, if a Holder converts a Security, when Combination Settlement is applicable to such Security and the Daily Settlement Amount for any VWAP Trading Day during the Cash Settlement Averaging Period applicable to such Security:

 (1) is calculated based on a Conversion Rate adjusted on account of any event described in Sections 4.04(a) through
(e) hereof; and 
 (2) includes any shares of Common Stock that, but for this provision, would entitle their holder to
participate in such event; 
 then, although the Company will otherwise treat such Holder as the holder of record of such shares of Common Stock
on the last VWAP Trading Day of such Cash Settlement Averaging Period, the Company will not permit such Holder to participate in such event on account of such shares of Common Stock. 

(g) Poison Pill. If a Holder converts a Security, to the extent the Company has a rights plan in effect, the Holder
converting such Security will receive, in addition to any shares of Common Stock otherwise received in connection with such conversion, the rights under the rights plan with respect to such shares, unless prior to such conversion, the rights have
separated from the Common Stock, in which case, and only in such case, the Conversion Rate will be adjusted at the time of separation as if the Company distributed to all holders of the Common Stock, shares of Capital Stock, evidences of
indebtedness, assets, property, rights, options or warrants as described in Section 4.04(c) hereof, subject to readjustment in the event of the expiration, termination or redemption of such rights. 

(h) Deferral of Adjustments. Notwithstanding anything to the contrary herein, except on and after the first VWAP Trading
Day of any Cash Settlement Averaging Period with respect to a Security and on or prior to the last VWAP Trading Day of such Cash Settlement Averaging Period, the Company will not be required to adjust the Conversion Rate unless such adjustment would
require an increase or decrease of at least one percent; provided, however, that any such minor adjustments that are not required to be made will be carried forward and taken into account in any subsequent adjustment, and
provided, further, that any such adjustment of 

  
 38 

 
less than one percent that has not been made shall be made upon the occurrence of (i) the Effective Date for any Make-Whole Fundamental Change and (ii) in the case of any Security to
which Physical Settlement applies, upon the Conversion Date, and in the case of a Security to which Cash Settlement or Combination Settlement applies, on the first VWAP Trading Day of the applicable Cash Settlement Averaging Period. In addition, the
Company shall not account for such deferrals when determining whether any of the conditions to conversion have been satisfied. 

(i) Limitation on Adjustments. Except as stated in this Section 4.04, the Company will not adjust the Conversion Rate for the
issuance of shares of Common Stock or any securities convertible into or exchangeable for shares of Common Stock or the right to purchase shares of the Common Stock or such convertible or exchangeable securities. If, however, the application of the
formulas in Sections 4.04(a) through (e) hereof would result in a decrease in the Conversion Rate, then, except to the extent of any readjustment to the Conversion Rate, no adjustment to the Conversion Rate will be made (other than as a result
of a reverse share split, share combination or readjustment to the Conversion Rate). 
 In addition, notwithstanding anything to
the contrary herein, the Conversion Rate will not be adjusted: 
 (1) on account of stock repurchases that are not tender
offers referred to in Section 4.04(e) hereof, including structured or derivative transactions, or transactions pursuant to a stock repurchase program approved by the Board of Directors or otherwise; 

(2) upon the issuance of any shares of Common Stock pursuant to any present or future plan providing for the reinvestment of dividends
or interest payable on the Company’s securities and the investment of additional optional amounts in shares of Common Stock under any plan; 
 (3) upon the issuance of any shares of Common Stock or options or rights to purchase those shares pursuant to any present or future employee, director or consultant benefit plan, program or agreement of
or assumed by the Company or any of its Subsidiaries; 
 (4) upon the issuance of any shares of Common Stock pursuant to any
option, warrant, right or exercisable, exchangeable or convertible security not described in the preceding bullet and outstanding as of the date the Securities were first issued; 

(5) for a change in the par value of the Common Stock; 
 (6) for accrued and unpaid interest on the Securities, if any; or 
 (7) for an
event otherwise requiring an adjustment under this Indenture if such event is not consummated. 
 In addition, before taking any
action which would cause an adjustment to the Conversion Rate such that the Conversion Price per share of Common Stock would be less than the par value of the Common Stock issuable upon conversion of the Securities, the Company shall take all

  
 39 

 
corporate actions that may, in the opinion of its counsel, be necessary so it may validly and legally issue shares of Common Stock at such adjusted Conversion Rate. 

(j) For purposes of this Section 4.04, the number of shares of Common Stock at any time outstanding shall not include shares held in
the treasury of the Company so long as the Company does not pay any dividend or make any distribution on shares of Common Stock held in the treasury of the Company, but shall include shares issuable in respect of scrip certificates issued in lieu of
fractions of shares of Common Stock. 
 Section 4.05 Adjustment of Prices and Voluntary Adjustments. 

(a) Adjustments of Prices. Whenever any provision of this Indenture requires the Company to calculate the Last Reported
Sale Prices, the Daily VWAPs or any function thereof, including the number of shares of Common Stock that would be deliverable, over a span of multiple days (including during a Cash Settlement Averaging Period), the Company will make appropriate
adjustments to each to account for any adjustment to the Conversion Rate that becomes effective, or any event requiring an adjustment to the Conversion Rate where the Effective Date, Ex-Dividend Date or Offer Expiration Date of the event occurs, at
any time during the period when such Last Reported Sale Prices, the Daily VWAPs or functions thereof, including the number of shares of Common Stock that would be deliverable, are to be calculated. 

(b) Voluntary Adjustments. To the extent permitted by applicable law and subject to compliance with the listing standards
of The NASDAQ Global Select Market, the Company is permitted to increase the Conversion Rate of the Securities by any amount for a period of at least 20 Business Days if the Board of Directors determines that such increase would be in the
Company’s best interest. The Company may also (but is not required to) increase the Conversion Rate to avoid or diminish income tax to holders of Common Stock or rights to purchase shares of Common Stock in connection with a dividend or
distribution of shares (or rights to acquire shares) or similar event. 
 Section 4.06 Adjustment to Conversion Rate upon
Conversion in Connection with a Make-Whole Fundamental Change. 
 (a) Increase in the Conversion Rate. If a
Make-Whole Fundamental Change occurs and a Holder elects to convert its Securities in connection with such Make-Whole Fundamental Change, the Company shall, under the circumstances set forth in this Section 4.06, increase the Conversion Rate
for the Securities so surrendered for conversion by a number of additional shares of Common Stock (the “Additional Shares”), as set forth in this Section 4.06. A conversion of Securities shall be deemed for these purposes to be
“in connection with” a Make-Whole Fundamental Change if the relevant Conversion Notice is received by the Conversion Agent during the period from, and including, the Effective Date of the Make-Whole Fundamental Change up to, and including,
the Close of Business on the Business Day immediately prior to the related Fundamental Change Purchase Date or, if such Make-Whole Fundamental Change is not a Fundamental Change, the 35th Business Day immediately following the Effective Date for
such Make-Whole Fundamental Change. 

  
 40 

 (b) Cash Mergers. Upon surrender of Securities for conversion in connection
with a Make-Whole Fundamental Change, the Company shall, at its option, satisfy its conversion obligation by Physical Settlement, Cash Settlement or Combination Settlement. Notwithstanding anything to the contrary herein, if the consideration paid
to holders of the Common Stock in any Make-Whole Fundamental Change described in Clause (2) of the definition of Fundamental Change is comprised entirely of cash, then, for any conversion of Securities following the Effective Date of such
Make-Whole Fundamental Change, the payment and delivery obligations upon the conversion of a Security shall be calculated based solely on the Stock Price for such Make-Whole Fundamental Change and shall, for each $1,000 principal amount of
Securities converted, be deemed to be an amount of cash equal to the product of (i) the Conversion Rate in effect on the applicable Conversion Date (as increased by any number of Additional Shares required by this Section 4.06)
multiplied by (ii) such Stock Price. In such event, the Company will determine the conversion obligation and pay such amount of cash to a converting Holder on the third Business Day following the applicable Conversion Date. Otherwise,
the Company will settle any conversion of the Securities following the Effective Date for a Make-Whole Fundamental Change in accordance with Section 4.02 hereof (but subject to Section 4.07 hereof). 

(c) Determining the Number of Additional Shares. The number of Additional Shares, if any, by which the Conversion Rate will
be increased for a Holder that converts its Securities in connection with a Make-Whole Fundamental Change shall be determined by reference to the table attached as Schedule A hereto, based on the date on which the Make-Whole Fundamental
Change occurs or becomes effective (the “Effective Date”) and the price (the “Stock Price”) paid (or deemed paid) per share of the Common Stock in the Make-Whole Fundamental Change. If the holders of the Common
Stock receive only cash in a Make-Whole Fundamental Change described in clause (2) of the definition of Make-Whole Fundamental Change, the Stock Price shall be the cash amount paid per share. Otherwise, the Stock Price shall be the average of
the Last Reported Sale Prices of the Common Stock over the ten consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the Effective Date of the Make-Whole Fundamental Change. 

(d) Interpolation and Limits. The exact Stock Prices and Effective Dates may not be set forth in the table in
Schedule A, in which case: 
 (1) If the Stock Price is between two Stock Prices in the table or the Effective Date
is between two Effective Dates in the table, the number of Additional Shares shall be determined by a straight-line interpolation between the number of Additional Shares set forth for the higher and lower Stock Prices and the earlier and later
Effective Dates, as applicable, based on a 365-day year. 
 (2) If the Stock Price is greater than $12.00 per share (subject to
adjustment in the same manner as the Stock Prices set forth in the column headings of the table in Schedule A pursuant to Section 4.06(d)(4) hereof), the Conversion Rate shall not be increased. 

(3) If the Stock Price is less than $4.25 per share (subject to adjustments in the same manner as the Stock Prices set forth in the
column headings of the table in Schedule A pursuant to Section 4.06(d)(4) hereof), the Conversion Rate shall not be increased. 

  
 41 

 Notwithstanding the foregoing, in no event will the Conversion Rate be increased on account
of a Make-Whole Fundamental Change to exceed 235.2941 shares of Common Stock per $1,000 principal amount of Securities, subject to adjustments in the same manner as the Conversion Rate is required to be adjusted as set forth in Section 4.04
hereof. 
 (4) The Stock Prices set forth in the column headings of the table in Schedule A hereto shall be
adjusted as of any date on which the Conversion Rate of the Securities is otherwise required to be adjusted. The adjusted Stock Prices shall equal the Stock Prices applicable immediately prior to such adjustment, multiplied by a fraction, the
numerator of which is the Conversion Rate immediately prior to such adjustment giving rise to the Stock Price adjustment and the denominator of which is the Conversion Rate as so adjusted. The number of Additional Shares set forth in such table
shall be adjusted in the same manner and at the same time as the Conversion Rate is required to be adjusted as set forth in Section 4.04. 
 (e) Notices. The Company shall notify the Holders of the Effective Date of any Make-Whole Fundamental Change and issue a press release announcing such Effective Date no later than five
Business Days after such Effective Date. 
 Section 4.07 Effect of Recapitalization, Reclassification, Consolidation, Merger
or Sale. 
 (a) Merger Events. In the case of: 

(1) any recapitalization, reclassification or change of the Common Stock (other than a change in par value, or from par value to no par
value, or from no par value to par value, or as a result of a split, subdivision or combination for which an adjustment was made pursuant to Section 4.04(a) hereof); 
 (2) any consolidation, merger or combination involving the Company; 
 (3) any
sale, lease or other transfer to a third party of the consolidated assets of the Company and its Subsidiaries substantially as an entirety; or 
 (4) any statutory share exchange; 
 and, in each case, as a result of which the Common Stock would
be converted into, or exchanged for, stock, other securities, other property or assets (including cash or any combination thereof) (any such event, a “Merger Event,” any such stock, other securities, other property or assets,
“Reference Property,” and the amount and kind of Reference Property that a holder of one share of Common Stock is entitled to receive in the applicable Merger Event (or if as a result of the applicable Merger Event, each share of
Common Stock is converted into the right to receive more than a single type of consideration (determined based in part upon any form of stockholder election), the per-share of Common Stock weighted average of the types and amounts of Reference
Property received by the holders of Common Stock that affirmatively make such an election) a “Unit of Reference Property”) then, at the effective time of such Merger Event, the right to convert each $1,000 principal amount of
Securities will, without the consent of the Holders, be changed into a right to convert each $1,000 principal amount of Securities into or based on a number of Units of Reference Property equal to the applicable Conversion Rate and,

  
 42 

 
prior to or at the effective time of such Merger Event, the Company or the successor or purchasing Person, as the case may be, shall execute with the Trustee a supplemental indenture (which shall
comply with the Trust Indenture Act as in force at the date of execution of such supplemental indenture) providing for such change in the right to convert each $1,000 principal amount of Securities; provided, however, that (x) the
Company will continue to have the right to determine the form of consideration to be paid and delivered, as the case may be, pursuant to Section 4.03(a)(2) hereof and (y)(i) any amount payable in cash upon conversion of the Securities in
accordance with Sections 4.03 and 4.06 hereof shall continue to be payable in cash, (ii) the number of shares of Common Stock that the Company would have been required to deliver upon conversion of the Securities in accordance with
Sections 4.03 and 4.06 hereof shall instead be deliverable in Units of Reference Property and (iii) the Daily VWAP will be calculated based on the amount and kind of a Unit of Reference Property and the definitions of VWAP Trading Day and
VWAP Market Disruption Event shall be determined by reference to the components of a Unit of Reference Property. The Company shall notify the Holders of the Unit of Reference Property as soon as practicable after such determination is made.

 The Company shall not become a party to any Merger Event unless its terms are consistent with this Section 4.07. Such
supplemental indenture described in the immediately preceding paragraph shall provide for adjustments which shall be as nearly equivalent to the adjustments provided for in this Article 4 in the judgment of the Board of Directors or the board
of directors of the successor Person. 
 (b) Notice of Supplemental Indentures. The Company shall cause notice of
the execution of such supplemental indenture to be mailed to each Holder, at the address of such Holder as it appears on the register of the Securities maintained by the Registrar, within 20 calendar days after execution thereof. Failure to deliver
such notice shall not affect the legality or validity of such supplemental indenture. The above provisions of this Section 4.07 shall similarly apply to successive Merger Events. 

(c) Prior Notice. In addition, at least 20 Scheduled Trading Days before any Merger Event, the Company shall give notice to
Holders of such Merger Event, or, if the Company has not publicly announced such Merger Event at such time, as promptly as practicable after publicly announcing such Merger Event. In any such notice, the Company shall also specify the composition of
the Unit of Reference Property for such Merger Event, or, if the Company has not determined the composition of such Unit of Reference Property at such time, the Company will provide an additional notice to Holders that states the composition of such
Unit of Reference Property as promptly as practicable after determining its composition. 
 Section 4.08 Stock Issued upon
Conversion. 
 (a) Reservation of Shares. To the extent necessary to satisfy its obligations under this
Indenture, prior to issuing any shares of Common Stock, the Company will reserve out of its authorized but unissued shares of Common Stock a sufficient number of shares of Common Stock to permit the conversion of the Securities. 

(b) Certain Other Covenants. The Company covenants that all shares of Common Stock that may be issued upon conversion of
Securities shall be newly issued shares or 

  
 43 

 
treasury shares, shall be duly authorized, validly issued, fully paid and non-assessable and shall be free from preemptive rights and free from any tax, lien or charge (other than those created
by the Holder or due to a change in registered owner). 
 The Company shall list or cause to have quoted any shares of Common
Stock to be issued upon conversion of Securities on each national securities exchange or over-the-counter or other domestic market on which the Common Stock is then listed or quoted. 

Section 4.09 Responsibility of Trustee. The Trustee and any Conversion Agent, Registrar, Bid Solicitation Agent or Paying Agent
(in each case, if other than the Company) shall not at any time be under any duty or responsibility to any Holder of Securities to determine or calculate amounts to be paid or for monitoring the price of the Common Stock or be charged with any
knowledge of or have any duties to monitor any Measurement Period. These calculations include, but are not limited to, determinations of the Last Reported Sale Price of the Common Stock, accrued interest payable on the Securities, the Daily VWAP,
the Daily Conversion Value, the Daily Settlement Amount and the Conversion Rate of the Securities. Further, the Trustee and any Conversion Agent, Registrar, Bid Solicitation Agent or Paying Agent (in each case, if other than the Company) shall not
at any time be under any duty or responsibility to any Holder of Securities to determine whether any facts exist which may require any adjustment of the Conversion Rate, or to confirm the accuracy of any such adjustment when made or the
appropriateness of the method employed, or herein or in any supplemental indenture provided to be employed, in making the same. The Trustee and any other Conversion Agent shall not be accountable with respect to the validity or value (or the kind or
amount) of any shares of Common Stock or of any other securities or property that may at any time be issued or delivered upon the conversion of any Securities; and the Trustee and the Conversion Agent make no representations with respect thereto.
Neither the Trustee nor any Conversion Agent shall be responsible for any failure of the Company to issue, transfer or deliver any shares of Common Stock or stock certificates or other securities or property or cash upon the surrender of any
Securities for the purpose of conversion or to comply with any of the duties, responsibilities or covenants of the Company contained in this Article 4. The rights, privileges, protections, immunities and benefits given to the Trustee, including
its right to be compensated, reimbursed, and indemnified, are extended to, and shall be enforceable by, the Trustee in each of its capacities hereunder, including its capacity as Conversion Agent. 

Section 4.10 Notice to Holders 
 (a) Prior to Certain Actions. (1) In case of any: 
 (A) action by the Company or one of its Subsidiaries that would require an adjustment in the Conversion Rate pursuant to Section 4.04(a), (b), (c), (d), (e), (g) or (h); or 

(B) voluntary or involuntary dissolution, liquidation or winding-up of the Company; 

then, in each case (unless notice of such event is otherwise required pursuant to another provision of this Indenture), the Company shall cause to be
filed with the Trustee and the 

  
 44 

 
Conversion Agent (if other than the Trustee) and to be delivered to each Holder, as promptly as possible but in any event at least 15 calendar days prior to the applicable date hereinafter
specified, a notice stating (i) the date on which a record is to be taken for the purpose of such action by the Company or one of its Subsidiaries or, if a record is not to be taken, the date as of which the holders of Common Stock of record
are to be determined for the purposes of such action by the Company or one of its Subsidiaries, or (ii) the date on which such dissolution, liquidation or winding-up is expected to become effective or occur, and the date as of which it is
expected that holders of Common Stock of record shall be entitled to exchange their Common Stock for securities or other property deliverable upon such dissolution, liquidation or winding-up. Failure to give such notice, or any defect therein,
shall not affect the legality or validity of such action by the Company or one of its Subsidiaries, dissolution, liquidation or winding-up. 
 (2) Voluntary Increases. If the Company increases the Conversion Rate pursuant to Section 4.05(b), the Company shall deliver notice to the Holders at least 15 calendar days prior to the date
on which such increase will become effective, which notice shall state the date on which such increased will become effective and the amount by which the Conversion Rate will be increased. 

(b) After Certain Actions and Events. Whenever an adjustment to the Conversion Rate becomes effective pursuant to Sections
4.04, 4.05 or 4.06 hereof, the Company will (i) file with the Trustee an Officer’s Certificate stating that such adjustment has become effective, the Conversion Rate, and the manner in which the adjustment was computed and
(ii) deliver notice to the Holders stating that such adjustment has become effective and the Conversion Rate or conversion privilege as adjusted. Failure to give any such notice, or any defect therein, shall not affect the validity of any such
adjustment. 
 ARTICLE 5. 
 SUBORDINATION 
 Section 5.01 Agreement to Subordinate. The Company
agrees, and each Holder by accepting a Security agrees, that the Indebtedness evidenced by the Securities (other than with respect to Obligations of the Securities that are secured by a pledge of the Escrow Account in accordance with Article 7
hereof and the assets therein pursuant to the Pledge and Escrow Agreement, solely to the extent of the assets therein and proceeds thereof) is subordinated in right of payment, to the extent and in the manner provided in this Article 5, to the prior
payment in full, in cash or other payment satisfactory to the holders of Senior Indebtedness, of all Senior Indebtedness (whether outstanding on the date hereof or hereafter created, incurred, assumed or guaranteed), and that the subordination is
for the benefit of the holders of Senior Indebtedness. 
 Section 5.02 Liquidation; Dissolution; Bankruptcy. 

(a) Upon any distribution to creditors of the Company in a liquidation or dissolution of the Company or in a bankruptcy, reorganization,
insolvency, receivership or similar proceeding relating to the Company or its property, in an assignment for the benefit of creditors or in any marshaling of the Company’s assets and liabilities, in each case other than with respect to
Obligations of the Securities that are secured by a pledge of the Escrow Account in accordance with Article 7 hereof and the assets therein pursuant to the Pledge and Escrow 

  
 45 

 
Agreement, solely to the extent of the assets therein and proceeds thereof, holders of Senior Indebtedness will be entitled to receive payment in full, in cash or other payment satisfactory to
the holders of Senior Indebtedness, of all Obligations due in respect of such Senior Indebtedness (including interest after the commencement of any bankruptcy proceeding at the rate specified in the applicable Senior Indebtedness) before the Holders
of Securities will be entitled to receive any payment of principal of and interest on, the Redemption Price or the Fundamental Change Purchase Price of, or the cash portion of the Company’s conversion obligation (if the Company has elected Cash
Settlement or Combination Settlement) upon conversion of the Securities. 
 (b) To the extent any payment of Senior Indebtedness
is declared to be fraudulent or preferential, set aside or required to be paid to any receiver, trustee in bankruptcy, liquidating trustee, agent or other similar Person under any bankruptcy, reorganization, insolvency, receivership or similar
proceeding, the Senior Indebtedness or part thereof originally intended to be satisfied shall be deemed to be reinstated and outstanding as if such payment had not occurred and the provisions of this Article 5 will be applied accordingly.

 Section 5.03 Default on Senior Indebtedness. 
 (a) The Company may not make any payment or distribution (other than with respect to Obligations of the Securities that are secured by a pledge of the Escrow Account in accordance with Article 7 hereof
and the assets therein pursuant to the Pledge and Escrow Agreement, solely to the extent of the assets therein and proceeds thereof) to the Trustee or any Holder in respect of Obligations with respect to the Securities and may not acquire from the
Trustee or any Holder any Securities for cash or property until all principal and other Obligations with respect to the Senior Indebtedness have been paid in full if: 
 (1) a default in the payment of principal, premium, if any, accrued and unpaid interest, if any, or any other Obligation due on any Senior Indebtedness (a “Payment Default”) occurs and is
continuing (including a payment that has become due as a result of the acceleration of any Senior Indebtedness); or 
 (2) any
other default (a “Nonpayment Default”) occurs and is continuing on the Senior Indebtedness that permits holders of the Senior Indebtedness to accelerate its maturity and the Trustee receives a notice of such default (a
“Payment Blockage Notice”) from the Company or the Representative. The Trustee shall promptly deliver a copy of any Payment Blockage Notice received by it to the Company and the Company shall promptly deliver such copy to all
holders of Senior Indebtedness. If the Representative shall, within 10 calendar days of their receipt thereof, deliver to the Company and the Trustee a notice rescinding such Payment Blockage Notice, such Payment Blockage Notice shall be deemed not
to have been delivered for all purposes of the Indenture. If the Trustee receives any such Payment Blockage Notice, no subsequent Payment Blockage Notice will be effective for purposes of this Section 5.03 unless and until at least 365 calendar
days have elapsed since the delivery of the immediately prior Payment Blockage Notice. 
 For the avoidance of doubt, the foregoing shall not
prevent the Holders of the Securities from receiving payments from the Escrow Account pursuant to Article 7 hereof. 

  
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 (b) The Company may and will resume payments on and distributions in respect of the
Securities and may acquire them upon the earlier of: 
 (1) in the case of a Payment Default, upon the date upon which such
default is cured or waived, and 
 (2) in the case of a Nonpayment Default, upon the earliest of (w) the date on which
such Nonpayment Default is cured or waived, (x) 91 calendar days after the date the Senior Indebtedness is paid in full, (y) 179 calendar days after the date on which the applicable Payment Blockage Notice is received, or (z) the date
the Payment Blockage Notice is rescinded, unless the maturity of the Senior Indebtedness has been accelerated (in which event the foregoing subclause (1) shall apply), if the Indenture otherwise permits such payment, distribution or acquisition
at the time of such payment, distribution or acquisition. 
 Section 5.04 Acceleration of Securities. If payment of the
Securities is accelerated because of an Event of Default, the Company may not make, directly or indirectly through any Subsidiary or other Person, any payment or distribution to the Trustee or any Holder in respect of Obligations with respect to the
Securities and may not acquire from the Trustee or any Holder any Securities for cash or property until all principal and other Obligations with respect to the Senior Indebtedness have been paid in full or such acceleration is rescinded in
accordance with the terms of this Supplemental Indenture. The Company shall promptly notify holders of Senior Indebtedness of any such acceleration. 
 Section 5.05 When Distribution Must Be Paid Over. In the event that the Trustee or any Holder of the Securities receives any payment of any Obligations with respect to the Securities at a time when
the payment is prohibited by Section 5.03 or Section 5.04, such payment will be held by the Trustee or such Holder, as the case may be, in trust for the benefit of, and will be paid forthwith over and delivered, upon proper written
request, to, the holders of Senior Indebtedness as their interests may appear or their Representative, if any, under the agreement, indenture or other document (if any) pursuant to which Senior Indebtedness may have been issued, as their respective
interests may appear, for application to the payment of all Obligations with respect to Senior Indebtedness remaining unpaid to the extent necessary to pay such Obligations in full in accordance with their terms, after giving effect to any
concurrent payment or distribution to or for the holders of Senior Indebtedness. 
 With respect to the holders of Senior
Indebtedness, the Trustee undertakes to perform only those obligations on the part of the Trustee as are specifically set forth in this Article 5, and no implied covenants or obligations with respect to the holders of Senior Indebtedness will be
read into this Indenture against the Trustee. The Trustee will not be deemed to owe any fiduciary duty to the holders of Senior Indebtedness, and will not be liable to any such holders if the Trustee pays over or distributes to or on behalf of
Holders or the Company or any other Person money or assets to which any holders of Senior Indebtedness are then entitled by virtue of this Article 5, except if such payment is made as a result of the willful misconduct or gross negligence of the
Trustee. 
 Section 5.06 Notice by Company. The Company will promptly notify the Trustee and the Paying Agent in writing
of any facts known to the Company that would cause a payment of 

  
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any Obligations with respect to the Securities to violate this Article 5, but failure to give such notice will not affect the subordination of the Securities to the Senior Indebtedness as
provided in this Article 5. 
 Section 5.07 Subrogation. After all Senior Indebtedness is paid in full and until the
Securities are paid in full, Holders of Securities will be subrogated (equally and ratably with all other Indebtedness pari passu with the Securities) to the rights of holders of Senior Indebtedness to receive distributions applicable to Senior
Indebtedness to the extent that distributions otherwise payable to the Holders of Securities have been applied to the payment of Senior Indebtedness. A distribution made under this Article 5 to holders of Senior Indebtedness that otherwise would
have been made to Holders of Securities is not, as between the Company and Holders, a payment by the Company on the Securities. 

Section 5.08 Relative Rights. This Article 5 defines the relative rights of Holders of Securities and holders of Senior
Indebtedness. Nothing in this Supplemental Indenture will: 
 (a) impair, as between the Company and Holders of Securities, the
obligation of the Company, which is absolute and unconditional, to pay principal of, and interest, if any, on, the Fundamental Change Repurchase Price or Redemption Price of, and to pay or deliver any amount due upon conversion of, the Securities in
accordance with their terms; 
 (b) affect the relative rights of Holders of Securities and creditors of the Company other than
their rights in relation to holders of Senior Indebtedness; or 
 (c) prevent the Trustee or any Holder of Securities from
exercising its available remedies upon a Default or Event of Default, subject to the rights of holders and owners of Senior Indebtedness to receive distributions and payments otherwise payable to Holders of Securities. 

If the Company fails because of this Article 5 to pay principal of, or interest, if any, on, the Redemption Price of, the Fundamental
Change Repurchase Price of, or to pay or deliver any amount due upon conversion of, the Securities in accordance with their terms, the failure is still a Default or Event of Default. 

Section 5.09 Subordination May Not Be Impaired by Company. No right of any holder of Senior Indebtedness to enforce the
subordination of the Indebtedness evidenced by the Securities may be impaired by any act or failure to act by the Company or any Holder or by the failure of the Company or any Holder to comply with this Supplemental Indenture. 

Section 5.10 Distribution or Notice to Representative or Holders of Senior Indebtedness. Whenever a distribution is to be made or
a notice given to holders of the Senior Indebtedness, the distribution may be made and the notice given to their Representative, if they have appointed one, and if no Representative has been appointed by the holders of any series of Senior
Indebtedness, such distribution or notice shall be made or given directly to such holders. 
 Upon any payment or distribution
of assets of the Company referred to in this Article 5, the Trustee and the Holders of Securities will be entitled to rely upon any order or decree made by any court of competent jurisdiction or upon any certificate of such

  
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Representative or of the liquidating trustee or agent or other Person making any distribution to the Trustee or to the Holders of Securities for the purpose of ascertaining the Persons entitled
to participate in such distribution, the holders of the Senior Indebtedness and other Indebtedness of the Company, the amount thereof or payable thereon, the amount or amounts paid or distributed thereon and all other facts pertinent thereto or to
this Article 5. 
 Section 5.11 Rights of Trustee and Paying Agent. Notwithstanding the provisions of this Article 5 or
any other provision of the Indenture, the Trustee will not be charged with knowledge of the existence of any facts that would prohibit the making of any payment or distribution by the Trustee, and the Trustee and the Paying Agent may continue to
make payments on the Securities, unless the Trustee has received at its Corporate Trust Office at least three Business Days prior to the date of such payment written notice of facts that would cause the payment of any Obligations with respect to the
Securities to violate this Article 5, except for any acceleration of the Securities prior to making any such payment or distribution which is known by any officer of the Trustee prior to making any such payment or distribution. The notice may only
be given by the Company or a Representative. For the avoidance of doubt, no such notice shall constitute a Payment Blockage Notice unless delivered in accordance with Section 5.03(a)(2). Nothing in this Article 5 will impair the claims of, or
payments to, the Trustee under or pursuant to Section 7.06 of the Base Indenture. 
 The Trustee in its individual or any
other capacity may hold Senior Indebtedness with the same rights it would have if it were not Trustee. Any Registrar, any Paying Agent, any Conversion Agent, any Bid Solicitation Agent and their successors hereunder may do the same with like rights.

 Section 5.12 Authorization to Effect Subordination; Filing Proof of Claim. Each Holder of Securities, by the
Holder’s acceptance thereof, authorizes and directs the Trustee on such Holder’s behalf to take such action as may be necessary or appropriate to effectuate the subordination as provided in this Article 5, and appoints the Trustee to act
as such Holder’s attorney-in-fact for any and all such purposes. If the Trustee does not file a proper proof of claim or proof of debt in the form required in any proceeding referred to in Section 7.13 of the Base Indenture at least 30
calendar days before the expiration of the time to file such claim, the Representative is hereby authorized to file an appropriate claim for and on behalf of the Holders of the Securities. 

Section 5.13 Reliance and Amendments. 
 (a) Each Holder of Securities by its acceptance thereof acknowledges and agrees that the subordination provisions set forth in this Article 5 are, and are intended to be, an inducement and a consideration
for each holder of any Senior Indebtedness, whether such Senior Indebtedness was created or acquired before or after the issuance of the Securities, to acquire and continue to hold, or to continue to hold, such Senior Indebtedness, and such holder
of Senior Indebtedness shall be deemed conclusively to have relied on such subordination provisions in acquiring and continuing to hold or in continuing to hold such Senior Indebtedness. 

(b) The provisions of this Article 5 may not be amended or modified without the written consent of the holders of all Senior
Indebtedness. In addition, any amendment to, or 

  
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waiver of, the provisions of this Article 5 that adversely affects the rights of the Holders of the Securities will require the consent of the Holders of a majority in aggregate principal amount
of Securities then Outstanding. 
 Section 5.14 No Layering. The Company will not incur, create, issue, assume, guarantee
or otherwise become liable for any Indebtedness that is senior in right of payment to the Securities, other than Senior Indebtedness. 
 Section 5.15 No Waiver of Subordination Provisions. Without in any way limiting the generality of Section 5.09, the holders of Senior Indebtedness may, at any time and from time to time,
without the consent of or notice to the Trustee or the Holders, without incurring responsibility to the Holders and without impairing or releasing the subordination provided in this Article 5 or the obligations hereunder of the Holders to the
holders of Senior Indebtedness, do any one or more of the following: 
 (a) change the manner, place or terms of payment or
extend the time of payment of, or renew or alter, Senior Indebtedness, or otherwise amend or supplement in any manner Senior Indebtedness or any instrument evidencing the same or any agreement under which Senior Indebtedness is outstanding;

 (b) sell, exchange, release or otherwise deal with any property pledged, mortgaged or otherwise securing Senior Indebtedness;

 (c) release any Person liable in any manner for the collection of Senior Indebtedness; and 

(d) exercise or refrain from exercising any rights against the Company and any other Person. 

ARTICLE 6. 

REDEMPTION 

Section 6.01 General. Article 3 of the Base Indenture shall not apply to the Securities. Instead, the provisions set forth in this
Article 6 shall, with respect to the Securities, supersede in their entirety Article 3 of the Base Indenture, and all references in the Base Indenture to Article 3 thereof shall, with respect to the Securities, be deemed to be references to the
redemption provisions set forth in this Article 6. 
 Section 6.02 Right to Redeem; Notices to Trustee. 

(a) The Securities are not redeemable by the Company prior to August 15, 2016. On or after August 15, 2016, except for the
Securities that the Company is required to repurchase in accordance with Article 3 hereof, the Company may redeem any or all of the Securities in cash at the Redemption Price (as defined below), provided that the Last Reported Sale Price of
the Common Stock for 20 or more Trading Days in a period of 30 consecutive Trading Days immediately prior to the date of the Redemption Notice exceeds 130% of the applicable Conversion Price in effect on such Trading Day; provided that the
Company may not redeem the Securities if the Redemption Date would be after the Maturity Date. 

  
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 (b) The redemption price at which the Securities are redeemable (the “Redemption
Price”) shall be equal to the sum of (i) 100% of the principal amount of Securities to be redeemed, payable in cash, plus (ii) accrued and unpaid interest, if any, to, but excluding, the Redemption Date, payable in cash;
provided, however, that if the Redemption Date is after a Regular Record Date and prior to the Interest Payment Date to which it relates, the Company will not pay accrued and unpaid interest to any Holder surrendering its Securities for
redemption, and shall instead pay the full amount of the interest due on such Interest Payment Date to the Holder of record on the Regular Record Date. 
 (c) The Company may not redeem any Securities if the principal amount of the Securities has been accelerated, and such acceleration has not been rescinded, on or prior to the relevant Redemption Date
(except in the case of an acceleration resulting from a default by the Company in the payment of the Redemption Price with respect to such Securities). 
 Section 6.03 Selection of Securities to be Redeemed. 
 If less than all the
Outstanding Securities are to be redeemed, the Trustee shall select the Securities to be redeemed in principal amounts of $1,000 or multiples of $1,000 by lot, on a pro rata basis or by another method the Trustee considers reasonable, fair and
appropriate in accordance with Applicable Procedures 
 Provisions of this Indenture that apply to Securities called for
redemption in whole also apply to Securities called for redemption in part. The Trustee shall notify the Company promptly of the Securities or portions of Securities to be redeemed. 

If a portion of any Holder’s Securities is selected for redemption and such Holder has converted a portion of its Securities before
termination of the conversion right with respect to the portion of the Security so selected, the converted portion of such Security shall be deemed (so far as may be) to be the portion selected for redemption. Securities which have been converted
during a selection of Securities to be redeemed may be treated by the Trustee as Outstanding for the purpose of such selection. 

Section 6.04 Notice of Redemption. 
 At least 70 calendar days but not more than 90 calendar days before a Redemption Date, the Company shall mail a notice of redemption by first-class mail, postage prepaid (or, in the case of Securities
held in book entry form, by electronic transmission), to the Trustee, the Paying Agent and each Holder of Securities to be redeemed in whole or in part at its last address as the same appears on the Security Register (a “Redemption
Notice”). 
 The Redemption Notice shall specify the Securities to be redeemed (including the CUSIP numbers, if any)
and shall state: 
 (a) that the Holders have a right to convert the Securities called for redemption upon satisfaction of the
requirements therefor set forth in this Indenture; 
 (b) the Redemption Date; 

  
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 (c) the Redemption Price; 

(d) the applicable Conversion Rate and any adjustments thereto; the relevant Settlement Method for Securities converted pursuant to
Section 4.01(b)(3) and, if applicable, the Specified Dollar Amount; 
 (e) the name and address of the Paying Agent and
Conversion Agent; 
 (f) that Securities called for redemption may be converted at any time before the Close of Business on the
second Scheduled Trading Day immediately preceding the Redemption Date; and 
 (g) the procedures a Holder must follow to
exercise rights under Section 6.02. 
 At the Company’s written request (which request must include the information listed
in clauses (a) through (f) above and be received by the Trustee not fewer than 75 calendar days prior (or such shorter period of time as may be acceptable to the Trustee) to the Redemption Date) the Trustee, in the name of and at the
expense of the Company, shall mail or cause to be mailed (or in the case of Securities held in book entry form, by electronic transmission) the Redemption Notice not fewer than 70 calendar days nor more than 90 calendar days prior to the Redemption
Date to each Holder to be redeemed as a whole or in part at its last address as the same appears on the Security Register. Such mailing shall be by first class mail. The notice, if mailed in the manner herein provided, shall be conclusively presumed
to have been duly given, whether or not the Holder receives such notice. In any case, failure to give such notice by mail or any defect in the notice to the Holder of any Security designated for redemption as a whole or in part shall not affect the
validity of the proceedings for the redemption of any other Security. Concurrently with the mailing of any such Redemption Notice, the Company shall issue a press release announcing such redemption, the form and content of which press release shall
be determined by the Company in its sole discretion. The failure to issue any such press release or any defect therein shall not affect the validity of the Redemption Notice or any of the proceedings for the redemption of any Security called for
redemption. 
 Section 6.05 Effect of Notice of Redemption. 

Once the Redemption Notice is delivered as set forth in Section 6.04, Securities called for redemption become due and payable on the
Redemption Date and at the Redemption Price, except for Securities that are converted in accordance with the terms of this Supplemental Indenture. Upon surrender to the Paying Agent, such Securities shall be paid at the Redemption Price. 

Section 6.06 Deposit of Redemption Price. 
 Prior to 11:00 a.m., New York City time, on the Redemption Date, the Company shall deposit with the Trustee or with the Paying Agent an amount of money (in immediately available funds if deposited on such
Trading Day) sufficient to pay the aggregate Redemption Price of all the Securities or portions thereof which are to be redeemed as of the Redemption Date. 

  
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 If the Paying Agent holds cash sufficient to pay the Redemption Price with respect to the
Securities to be redeemed on the Redemption Date in accordance with the terms of this Supplemental Indenture, then, immediately after the Redemption Date, (a) such Securities will cease to be Outstanding and interest shall cease to accrue
thereon (whether or not book-entry transfer of such Securities is made or such Securities have been delivered to the Paying Agent) and (b) all other rights of the Holders in respect thereof will terminate (other than the right to receive the
Redemption Price upon delivery or book-entry transfer of such Securities). 
 Section 6.07 Securities Redeemed in Part.

 Any Security which is to be redeemed only in part shall be surrendered at the office of the Paying Agent (with, if the
Company or the Trustee so requires, in the case of Physical Securities, due endorsement by, or a written instrument of transfer in substantially in the Form of Assignment and Transfer duly executed by, the Holder thereof or such Holder’s
attorney duly authorized in writing) and the Company shall execute and the Trustee shall authenticate and deliver to the Holder of such Security, without service charge, a new Security or Securities, of any authorized denomination as requested by
such Holder in aggregate principal amount equal to, and in exchange for, the portion of the principal amount of the Security so surrendered that is not redeemed; provided, that the Company shall not be required to (i) issue, register the
transfer of or exchange any Securities during a period beginning at the Open of Business 15 calendar days before the mailing of the Redemption Notice of the Securities and ending at the Close of Business on the earliest date on which the relevant
Redemption Notice is deemed to have been given to all Holders of Securities to be redeemed or (ii) register the transfer of or exchange any Securities so selected for redemption, in whole or in part, except the unredeemed portion of any
Securities being redeemed in part. 
 ARTICLE 7. 
 COLLATERAL SECURITY 
 Section 7.01 Collateral Security. 

(a) On the Issue Date of the initial Securities issued hereunder, the Company shall (i) enter into the Pledge and Escrow Agreement
and thereafter comply with the terms and provisions of such agreement and (ii) pledge the Pledged Collateral to the Escrow Agent for the benefit of the Trustee and the ratable benefit of the Holders in such amount as will be sufficient upon
receipt of scheduled interest and/or principal payments of such Pledged Collateral to provide for payment in full of the first six scheduled interest payments due on the Securities. The Pledged Collateral shall be pledged by the Company to the
Escrow Agent for the benefit of the Trustee and the ratable benefit of the Holders and shall be held by the Escrow Agent in the Pledge Account pending disposition pursuant to the Pledge and Escrow Agreement. The Pledged Collateral shall also secure
the due and punctual payment and performance of all obligations of the Company, whether now or hereafter existing, under the Securities, this Indenture and the Pledge and Escrow Agreement, including interest accrued on the Securities after the
commencement of a bankruptcy, reorganization or similar proceeding involving the Company. Notwithstanding the foregoing, the Pledged Collateral shall not secure obligations of the Company to issue and deliver shares of Common Stock (or other
Reference Property) upon conversion of the Securities, provided, however that the Pledged Collateral shall secure the 

  
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obligations of the Company to pay the principal of, and accrued and unpaid interest, if any, on the Securities in the event of an acceleration upon an Event of Default, including a failure by the
Company to comply with its obligations to convert the Securities as set forth in Section 9.02. 
 (b) Each Holder, by its
acceptance of a Security, consents and agrees to the terms of the Pledge and Escrow Agreement (including the provisions providing for foreclosure and release of the Pledged Collateral) as such agreement may be in effect or may be amended from time
to time in accordance with their terms, and authorizes and directs the Escrow Agent and the Trustee to enter into the Pledge and Escrow Agreement and to perform their respective obligations and exercise their respective rights under such agreement
in accordance therewith. The Company will do or cause to be done all such acts and things as may be necessary, or as may be required by the provisions of the Pledge and Escrow Agreement, to assure and confirm to the Escrow Agent and the Trustee the
security interest in the Pledged Collateral contemplated hereby, by the Pledge and Escrow Agreement or any part of such agreement, as from time to time constituted, so as to render the same available for the security and benefit of this Indenture
and of the Securities secured hereby, according to the intent and purposes herein and therein expressed. The Company shall take, or cause to be taken, any and all actions reasonably required to create and maintain, as security for the obligations of
the Company under this Indenture and the Securities, a valid, enforceable and perfected first priority lien in and on all the Pledged Collateral, in favor of the Escrow Agent for the benefit of the Trustee and the ratable benefit of the Holders,
superior to and prior to the rights of third Persons and subject to no other liens. 
 (c) The release of any portion of the
Pledged Collateral pursuant to the Pledge and Escrow Agreement will not be deemed to impair the security under this Indenture in contravention of the provisions hereof if and to the extent the Pledged Collateral are released pursuant to this
Indenture and the Pledge and Escrow Agreement. To the extent applicable, the Company shall cause Section 314(d) of the Trust Indenture Act relating to the release of property or securities from the lien and security interest of the Pledge and
Escrow Agreement and relating to the substitution therefor of any property or securities to be subjected to the lien and security interest of the Pledge and Escrow Agreement to be complied with. Any certificate or opinion required by
Section 314(d) of the Trust Indenture Act may be made by an Officer of the Company, except in cases where Section 314(d) of the Trust Indenture Act requires that such certificate or opinion be made by an independent Person, which Person
shall be an independent engineer, appraiser or other expert selected by the Company. The Company shall cause Section 314(b) of the Trust Indenture Act, relating to opinions of counsel regarding the lien under the Pledge and Escrow Agreement, to
be complied with. 
 (d) The Escrow Agent and the Trustee may, in their sole discretion and without the consent of the Holders,
on behalf of the Holders, take all reasonable actions in accordance with the Pledge and Escrow Agreement, necessary or appropriate in order to (i) enforce any of the terms of the Pledge and Escrow Agreement and (ii) collect and receive any
and all amounts payable in respect of the obligations of the Company under such agreement. The Escrow Agent and the Trustee shall have power (but not the obligation) to institute and to maintain such suits and proceedings as the they may reasonably
deem expedient to preserve or protect their interests and the interests of the Holders in the Pledged Collateral (including power to institute and maintain suits or proceedings to restrain the enforcement of or compliance with any legislative or
other governmental enactment, rule or order that may be unconstitutional or 

  
 54 

 
otherwise invalid if the enforcement of, or compliance with, such enactment, rule or order would impair the security interest hereunder or be prejudicial to the interests of the Holders, the
Escrow Agent or of the Trustee). 
 ARTICLE 8. 
 PARTICULAR COVENANTS OF THE COMPANY 
 Section 8.01 Payment of Principal,
Interest, Redemption Price and Fundamental Change Purchase Price. This Section 8.01 shall replace Section 4.01 of the Base Indenture in its entirety. 
 The Company covenants and agrees that it will cause to be paid the principal of (including the Fundamental Change Purchase Price and Redemption Price), and accrued and unpaid interest, if any, on each of
the Securities at the places, at the respective times and in the manner provided herein and in the Securities. 
 Section 8.02
Maintenance of Office or Agency. This Section 8.02 replaces Section 4.02 of the Base Indenture in its entirety. 
 The Company will maintain in Minneapolis, Minnesota, an office of the Paying Agent, an office of the Registrar and an office or agency where Securities may be surrendered for conversion
(“Conversion Agent”) and where notices and demands to or upon the Company in respect of the Securities and this Indenture may be served. The Company will give prompt written notice to the Trustee of the location, and any change in
the location, of such office or agency. If at any time the Company shall fail to maintain any such required office or agency or shall fail to furnish the Trustee with the address thereof, such presentations, surrenders, notices and demands may be
made or served at the Corporate Trust Office or the office or agency of the Trustee in Minneapolis, Minnesota. 
 The Company
may also from time to time designate co-registrars and one or more other offices or agencies where the Securities may be presented or surrendered for any or all such purposes and may from time to time rescind such designations; provided that
no such designation or rescission shall in any manner relieve the Company of its obligation to maintain an office or agency in Minneapolis, Minnesota for such purposes. The Company will give prompt written notice to the Trustee of any such
designation or rescission and of any change in the location of any such other office or agency. The terms “Paying Agent” and “Conversion Agent” include any such additional or other offices or agencies, as applicable. 

The Company hereby initially designates the Trustee as the Paying Agent, Registrar, Custodian, Conversion Agent, Transfer Agent and the
Corporate Trust Office, which shall be in the continental United States, shall be considered as one such office or agency of the Company for each of the aforesaid purposes. The Company hereby initially designates itself as the Bid Solicitation
Agent. 
 With respect to any Global Security, the Corporate Trust Office of the Trustee or any Paying Agent shall be the Place
of Payment where such Global Security may be presented or surrendered for payment or conversion or for registration of transfer or exchange, or where successor Securities may be delivered in exchange therefor; provided, however, that
any such 

  
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payment, conversion, presentation, surrender or delivery effected pursuant to the Applicable Procedures of the Depositary for such Global Security shall be deemed to have been effected at the
Place of Payment for such Global Security in accordance with the provisions of this Indenture. 
 Section 8.03 Appointments
to Fill Vacancies in Trustee’s Office. The Company, whenever necessary to avoid or fill a vacancy in the office of Trustee, will appoint, in the manner provided in Section 7.10 of the Base Indenture, a Trustee, so that there shall at
all times be a Trustee hereunder. 
 Section 8.04 Provisions as to Paying Agent. This Section 8.04 replaces
Section 4.03 of the Base Indenture in its entirety. 
 (a) If the Company shall appoint a Paying Agent other than the
Trustee, the Company will cause such Paying Agent to execute and deliver to the Trustee an instrument in which such agent shall agree with the Trustee, subject to the provisions of this Section 8.04: 

(1) that it will hold all sums held by it as such agent for the payment of the principal of, accrued and unpaid interest, if any, on,
the Redemption Price of, and the Fundamental Change Purchase Price for, the Securities in trust for the benefit of the holders of the Securities; 
 (2) that it will give the Trustee prompt written notice of any failure by the Company to make any payment of the principal of, accrued and unpaid interest, if any, on, the Redemption Price of, or the
Fundamental Change Purchase Price for, the Securities when the same shall be due and payable; and 
 (3) that at any time
during the continuance of an Event of Default, upon request of the Trustee, it will forthwith pay to the Trustee all sums so held in trust. 
 The Company shall, on or before each due date of the principal of, accrued and unpaid interest, if any, on, the Redemption Price of, and Fundamental Change Purchase Price for, the Securities, deposit with
the Paying Agent a sum sufficient to pay such principal, accrued and unpaid interest, the Redemption Price of, or Fundamental Change Purchase Price, as the case may be, and (unless such Paying Agent is the Trustee) the Company will promptly notify
the Trustee of any failure to take such action, provided that, if such deposit is made on the due date, such deposit must be received by the Paying Agent by 10:00 a.m., New York City time, on such date. 

(b) If the Company shall act as its own Paying Agent, it will, on or before each due date of the principal of, accrued and unpaid
interest, if any, on, the Redemption Price of, or Fundamental Change Purchase Price for, the Securities, set aside, segregate and hold in trust for the benefit of the Holders of the Securities a sum sufficient to pay such principal of, accrued and
unpaid interest, if any, on, the Redemption Price of, or Fundamental Change Purchase Price, as the case may be, so becoming due and will promptly notify the Trustee in writing of any failure to take such action and of any failure by the Company to
make any payment of the principal of, accrued and unpaid interest on, the Redemption Price of, or 

  
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Fundamental Change Purchase Price for, the Securities when the same shall become due and payable. 
 (c) Anything in this Section 8.04 to the contrary notwithstanding, (i) the agreement to hold sums in trust as provided in this Section 8.04 is subject to the provisions of
Section 10.04, and (ii) the Company may, at any time, for the purpose of obtaining a satisfaction and discharge of this Indenture, or for any other reason, pay or cause to be paid to the Trustee all sums held in trust by the Company or any
Paying Agent hereunder as required by this Section 8.04, such sums to be held by the Trustee upon the trusts herein contained and upon such payment by the Company or any Paying Agent to the Trustee, the Company or such Paying Agent shall be
released from all further liability with respect to such sums. 
 (d) Any money deposited with the Trustee or any Paying Agent,
or then held by the Company, in trust for the payment of the principal of, accrued and unpaid interest, if any, on, the Redemption Price of, or Fundamental Change Purchase Price for, any Security and remaining unclaimed for two years after such
principal, accrued and unpaid interest, if any, on, the Redemption Price of, or Fundamental Change Purchase Price for, such Security has become due and payable shall be paid to the Company on request of the Company contained in an Officer’s
Certificate, subject to any escheatment laws, or (if then held by the Company) shall be discharged from such trust; and the holder of such Security shall thereafter, as an unsecured general creditor, look only to the Company for payment thereof, and
all liability of the Trustee or such Paying Agent with respect to such trust money, and all liability of the Company as trustee thereof, shall thereupon cease; provided, however, that before the Trustee or such Paying Agent are
required to make any such repayment, the Company shall issue a press release that such money remains unclaimed and that, after a date specified therein, which shall not be less than thirty calendar days from the release of such press release, any
unclaimed balance of such money then remaining will be repaid to the Company. The Company shall make such press release available on its website. 
 Section 8.05 Existence. Subject to Article 12, the Company shall do or cause to be done all things necessary to preserve and keep in full force and effect its corporate existence. 

Section 8.06 Reports. 
 (a) This Section 8.06 replaces Section 5.03 of the Base Indenture in its entirety. 
 (1) The Company shall file with the Trustee, within 15 calendar days after it is required to file the same with the Commission (giving effect to any period provided by Rule 12b-25 under the Exchange Act),
copies of the quarterly and annual reports (on Form 10-K or Form 10-Q or any successor form) that it is required to file with the Commission pursuant to Section 13 or 15(d) of the Exchange Act, and to otherwise comply with Section 314(a)
of the Trust Indenture Act. Any such report, information or document that the Company files with the Commission through the EDGAR system will be deemed to be delivered to the Trustee for the purposes of this Section 8.06 at the time of such
filing through the EDGAR system. The Trustee shall have no responsibility whatsoever to determine if such filings have been made. 

  
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 (2) If at any time the Company is not subject to the reporting requirements of
Section 13 or 15(d) of the Exchange Act, the Company shall provide the Trustee and the Holders of the Securities with annual and quarterly reports containing substantially the same information as would have been required to be filed with the
Commission had the Company continued to have been subject to such reporting requirements. In such event, such annual and quarterly reports shall be provided at the times the Company would have been required to provide reports had it continued to
have been subject to such reporting requirements. 
 (3) Delivery of any such reports, information and documents to the Trustee
shall be for informational purposes only, and the Trustee’s receipt of such reports, information and documents shall not constitute constructive notice of any information contained therein or determinable from information contained therein,
including the Company’s compliance with any of its covenants hereunder (as to which the Trustee is entitled to rely exclusively on Officer’s Certificates). 
 Section 8.07 Pledge and Escrow Agreement. The Company shall maintain the Pledge and Escrow Agreement in full force and effect prior to its expiration in accordance with its terms, shall comply with
the terms thereof and shall not amend the Pledge and Escrow Agreement in any manner adverse to the holders of the Securities without the consent of the each Holder affected thereby. Simultaneously with the original issuance of the Securities, the
Company shall deliver Pledged Collateral to the Escrow Agent for deposit in the Escrow Account in the amount of $36,690,191.00 in immediately available funds. 
 Section 8.08 Officer’s Certificates. Subject to Section 13.12 of the Base Indenture, the Company shall deliver to the Trustee, within 120 days after the end of each fiscal year, an
Officer’s Certificate stating whether or not, to the knowledge of the signers thereof, the Company is in default in the performance and observation of any of the terms, provisions and conditions of this Indenture (without regard to any period
of grace or requirement of notice provided hereunder). If the Company is in default, such Officer’s Certificate shall specify all such Defaults and the nature and status thereof of which the signers have knowledge. 

Section 8.09 Further Instruments and Acts. Upon request of the Trustee, the Company will execute and deliver such further
instruments and do such further acts as may be reasonably necessary or proper to carry out more effectively the purposes of the Indenture. 
 ARTICLE 9. 
 REMEDIES 

Section 9.01 Amendments to the Base Indenture. The Event of Default provisions set forth in this Article 9 shall, with respect to
the Securities, supersede the entirety of Article 6 of the Base Indenture, and all references in the Base Indenture to Article 6 thereof and the provisions relating to Events of Default therein, as the case may be, shall, with respect to the
Securities, be deemed to be references to this Article 9 and the Events of Default provisions set forth in this Article 9, respectively. 
 Section 9.02 Events of Default. Each of the following events (and only the following events) shall be an “Event of Default” wherever used with respect to the Securities:

  
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 (a) default in any payment of interest on any Security when due and payable, whether or not
prohibited by Article 5 hereof, and the default continues (i) for any Interest Payment Date through and including August 15, 2015, for a period of ten (10) Business Days, or (ii) for any Interest Payment Date after
August 15, 2015, for a period of thirty (30) calendar days; 
 (b) default in the payment of the principal of any
Security (including the Fundamental Change Purchase Price) when due and payable on the Maturity Date, upon required repurchase, upon declaration of acceleration or otherwise, whether or not such payment is prohibited by Article 5 hereof; 

(c) failure by the Company to pay the Redemption Price of any Security on any Redemption Date, whether or not such payment is prohibited
by Article 5 hereof; 
 (d) failure by the Company to comply with its obligations under Article 4 hereof to convert the
Securities into cash, shares of Common Stock, or a combination of cash and shares of Common Stock, as applicable, in accordance with Article 4 hereof upon exercise of a Holder’s conversion right, whether or not any cash payment due upon
conversion is prohibited by Article 5 hereof and such failure continues for three (3) Scheduled Trading Days; 
 (e)
failure by the Company to comply with its obligations under Article 12 hereof; 
 (f) failure by the Company to issue a notice
in accordance with the provisions of Section 4.01(b)(4) or 4.01(b)(5) hereof or Section 3.01(b) hereof for a period of five (5) calendar days after such notice becomes due; 

(g) failure by the Company for sixty (60) calendar days after written notice from the Trustee or the Holders of at least 25% in
principal amount of the Securities then Outstanding (a copy of which notice, if given by Holders, must also to be given to the Trustee) has been received by the Company to comply with any of its other agreements contained in the Securities or this
Indenture (other than a covenant or warranty a default in whose performance or whose breach is elsewhere in this Section 9.02 specifically provided for or that is not applicable to the Securities), which notice shall state that it is a
“Notice of Default” hereunder; 
 (h) default by the Company or any Subsidiary of the Company with respect to
any mortgage, agreement or other instrument under which there may be outstanding, or by which there may be secured or evidenced any debt for money borrowed in excess of $20,000,000 in the aggregate of the Company and/or any such Subsidiary, whether
such debt now exists or shall hereafter be created, which default results (i) in such debt becoming or being declared due and payable, and such debt has not been discharged in full or such declaration rescinded or annulled within 30 calendar
days, or (ii) from a failure to pay the principal of any such debt when due and payable at its stated maturity, upon required repurchase, upon declaration or otherwise, and such defaulted payment shall not have been made, waived or extended
within 30 calendar days; 
 (i) the Company or any Significant Subsidiary of the Company shall commence a voluntary case or
other proceeding seeking the liquidation, reorganization or other relief with respect to the Company or such Significant Subsidiary or its debts under any 

  
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bankruptcy, insolvency or other similar law now or hereafter in effect or seeking the appointment of a trustee, receiver, liquidator, custodian or other similar official of the Company or such
Significant Subsidiary of the Company or any substantial part of the Company’s, or such Significant Subsidiary of the Company’s, property, or shall consent to any such relief or to the appointment of, or taking possession by, any such
official in an involuntary case or other proceeding commenced against it, or shall make a general assignment for the benefit of creditors, or shall fail generally to pay its debts as they become due; 

(j) an involuntary case or other proceeding shall be commenced against the Company or any Significant Subsidiary of the Company seeking
liquidation, reorganization or other relief with respect to the Company or such Significant Subsidiary of the Company or its debts under any bankruptcy, insolvency or other similar law now or hereafter in effect or seeking the appointment of a
trustee, receiver, liquidator, custodian or other similar official of the Company or such Significant Subsidiary of the Company or any substantial part of its property, and such involuntary case or other proceeding shall remain undismissed and
unstayed for a period of ninety consecutive calendar days; 
 (k) the Pledge and Escrow Agreement shall cease to be in full
force and effect or enforceable prior to August 15, 2015 in accordance with the terms thereof; or 
 (l) the failure by the
Company or any of its Significant Subsidiaries to pay any final judgments entered by a court or courts of competent jurisdiction in excess of $20,000,000 (excluding any amounts covered by insurance), which judgment is not paid, discharged, stayed,
vacated or otherwise satisfied for within 45 calendar days after (x) the date on which the right to appeal thereof has expired if no such appeal has commenced, or (y) the date on which all rights to appeal have been extinguished.

 Section 9.03 Acceleration; Rescission and Annulment. 

(a) If one or more Events of Default shall have occurred and be continuing (whatever the reason for such Event of Default and whether it
shall be voluntary or involuntary or be effected by operation of law or pursuant to any judgment, decree or order of any court or any order, rule or regulation of any administrative or governmental body), then, and in each and every such case (other
than an Event of Default specified in Section 9.02(i) or Section 9.02(j) with respect to the Company (and not solely with respect to a Significant Subsidiary of the Company)), unless the principal of all of the Securities shall have
already become due and payable, either the Trustee or the holders of at least 25% in aggregate principal amount of the Securities then Outstanding, by notice in writing to the Company (and to the Trustee if given by the Holders), may declare 100% of
the principal of, and accrued and unpaid interest, if any, on all the Securities to be due and payable immediately, and, subject to Section 5.04 hereof, upon any such declaration the same shall become and shall automatically be immediately due
and payable, anything in this Indenture or in the Securities contained to the contrary notwithstanding. If an Event of Default specified in Section 9.02(i) or Section 9.02(j) with respect to the Company (and not solely with respect to a
Significant Subsidiary of the Company) occurs and is continuing, the principal of, and accrued and unpaid interest, if any, on all Securities shall be immediately due and payable, subject to Section 5.04 hereof. 

  
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 (b) The Holders of a majority in aggregate principal amount of the Securities then
Outstanding, by written notice to the Company and to the Trustee, may waive all Defaults or Events of Default with respect to the Securities (other than a Default or an Event of Default resulting from a failure to pay the principal of, accrued and
unpaid interest on, or the Redemption Price or the Fundamental Change Purchase Price of a Security, the failure to pay or deliver the cash, shares of Common Stock or a combination of cash and shares of Common Stock, as the case may be, due upon
conversion of a Security, or the breach of any provision of this Indenture that cannot be modified or amended without the consent of each affected Holder) and rescind and annul such declaration of acceleration resulting from such Defaults or Event
of Defaults (other than a Default or an Event of Default resulting from a failure to pay the principal of, accrued and unpaid interest on, or the Fundamental Change Purchase Price or Redemption Price of a Security, the failure to pay or deliver the
cash, shares of Common Stock or a combination of cash and shares of Common Stock, as the case may be, due upon conversion of a Security, or the breach of any provision of this Indenture that cannot be modified or amended without the consent of each
affected Holder) and their consequences and such Default (other than a Default relating to the failure to pay principal on, accrued and unpaid interest on, or the Fundamental Change Purchase Price or Redemption Price of a Security, the failure to
pay or deliver the cash, shares of Common Stock or a combination of cash and shares of Common Stock, as the case may be, due upon conversion of a Security, or the breach of any provision of this Indenture that cannot be modified or amended without
the consent of each affected Holder) shall cease to exist, and any Event of Default arising therefrom shall be deemed to have been cured for every purpose of this Indenture, if: 

(1) rescission would not conflict with any judgment or decree of a court of competent jurisdiction; and 

(2) all existing Events of Default under this Indenture, other than the nonpayment of the principal of, and accrued and unpaid interest,
if any, on, the Redemption Price of or the Fundamental Change Purchase Price for, the Securities that shall have become due solely by such acceleration, shall have been cured or waived pursuant to Section 9.05 hereof; 

provided, that no such waiver or rescission and annulment shall extend to or shall affect any subsequent Default or Event of Default, or shall
impair any right consequent thereon. 
 Section 9.04 Supplementary Interest. 

(a) Notwithstanding any provisions of the Indenture to the contrary, to the extent the Company elects, the sole remedy for an Event of
Default arising under Section 9.02(g) relating to the Company’s failure to comply with Section 8.06(a) hereof (a “Reporting Event of Default”) will consist exclusively of the right to receive additional interest on
the Securities at a rate per year equal to (i) 0.25% per annum of the aggregate principal amount of the Securities Outstanding for each day during the 180-day period during which such Reporting Event of Default is continuing beginning on,
and including, the date on which such Reporting Event of Default first occurs (and has neither been waived nor cured), and (ii) 0.50% per annum of the aggregate principal amount of the Securities Outstanding for each day during the 185-day
period beginning on, and including, the 181st day on which such Reporting Event of Default is continuing (and neither waived nor cured) (“Supplementary Interest”). If the Company so

  
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elects, such Supplementary Interest shall be payable in the same manner and on the same dates as the stated interest payable on the Securities. On the 366th day after the date on which the Reporting Event of Default first
occurred (if such Reporting Event of Default has not been cured or waived prior to such 366th day), the Securities will be subject to acceleration as provided in Section 9.03 hereof. In no event shall Supplementary Interest accrue at a rate per year in excess of the applicable interest rate
specified in this Section 9.04(a), regardless of the number of Reporting Events of Default that could give rise to the requirement to pay Supplementary Interest. With regard to any Reporting Event of Default, no Supplementary Interest shall
accrue, and no right to declare the principal or other amounts due and payable in respect of the Securities shall exist, after such Reporting Event of Default has been cured. 
 (b) In the event (i) the Company does not elect to pay the Supplementary Interest following a Reporting Event of Default in accordance with this Section 9.04, or (ii) the Company elects to
pay the Supplementary Interest but does not pay the Supplementary Interest when due, the Securities will be subject to acceleration as provided in Section 9.03 hereof. 
 (c) In order to elect to pay the Supplementary Interest as the sole remedy during the 365-day period after the first occurrence of a Reporting Event of Default as described in Section 9.04(a), the
Company shall notify all Holders of the Securities, the Trustee and the Paying Agent in writing of such election prior to the beginning of such 365-day period. Upon the Company’s failure to timely give such notice, the Securities will be
immediately subject to acceleration as provided in Section 9.03 hereof. 
 (d) The provisions of this Section 9.04
will not affect the rights of Holders in the event of the occurrence of any other Event of Default. 
 Section 9.05 Waiver of
Past Defaults. The Holders of a majority in aggregate principal amount of the Notes at the time Outstanding may on behalf of the Holders of all of the Notes waive any past Default or Event of Default hereunder and its consequences except
(1) a default in the payment of accrued and unpaid interest, if any, on, or the principal (including any Redemption Price or Fundamental Change Purchase Price) of, the Notes when due that has not been cured, (2) a failure by the Company to
deliver the consideration due upon conversion of the Notes or (3) a default in respect of a covenant or provision hereof which under Article 11 cannot be modified or amended without the consent of each Holder of an outstanding Note affected.

 Section 9.06 Control by Majority. At any time, the Holders of a majority of the aggregate principal amount of the then
Outstanding Securities may direct the time, method and place of conducting any proceeding for any remedy available to the Trustee or for exercising any trust or power conferred on the Trustee. However, the Trustee may refuse to follow any direction
that conflicts with law or this Indenture or, subject to the Trustee’s duties under Article 7 of the Base Indenture and the Trust Indenture Act, that the Trustee determines to be unduly prejudicial to the rights of a Holder or to the
Trustee, or that would potentially involve the Trustee in personal liability unless the Trustee is offered indemnity or security reasonably satisfactory to it against any loss, liability or expense to the Trustee that may result from the
Trustee’s instituting such proceeding as the Trustee. Prior to taking any action hereunder, the Trustee will be entitled to indemnification satisfactory to it in its sole discretion against all losses and expenses caused by taking or not taking
such action. 

  
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 Section 9.07 Limitation on Suits. Subject to Section 9.08 hereof, no Holder may
pursue a remedy with respect to this Indenture or the Securities unless: 
 (a) such Holder has previously delivered to the
Trustee written notice that an Event of Default has occurred and is continuing; 
 (b) the Holders of at least 25% of the
aggregate principal amount of the then Outstanding Securities deliver to the Trustee a written request that the Trustee pursue a remedy with respect to such Event of Default; 
 (c) such Holder or Holders have offered and, if requested, provided to the Trustee indemnity reasonably satisfactory to the Trustee against any loss, liability or other expense of compliance with such
written request; 
 (d) the Trustee has not complied with such written request within 60 calendar days after receipt of such
written request and offer of indemnity; and 
 (e) during such 60-day period, the Holders of a majority of the aggregate
principal amount of the then Outstanding Securities did not deliver to the Trustee a direction inconsistent with such written request. 
 A Holder may not use this Indenture to prejudice the rights of any other Holder or to obtain a preference or priority over any other Holder, it being understood that the Trustee does not have any
affirmative duty to ascertain whether any usage of this Indenture by a Holder is unduly prejudicial to such other Holders. 

Section 9.08 Rights of Holders to Receive Payment and to Convert. Notwithstanding anything to the contrary elsewhere in this
Indenture and subject to Article 5 hereof, the right of any Holder to receive payment of the principal of, interest on, the Redemption Price of, or the Fundamental Change Purchase Price for, its Securities, on or after the respective due date, and
to convert its Securities and receive payment or delivery, as the case may be, of the consideration due with respect to such Securities in accordance with Article 4 hereof, or to bring suit for the enforcement of any such payment or conversion
rights, will not be impaired or affected without the consent of such Holder and will not be subject to the requirements of Section 9.07 hereof. 
 Section 9.09 Collection of Indebtedness; Suit for Enforcement by Trustee. Subject to Article 5 hereof, if an Event of Default specified in Sections 9.02(a), 9.02(b) or 9.02(c) hereof occurs
and is continuing, the Trustee is authorized to recover judgment in its own name and as trustee of an express trust against the Company for the whole amount of principal of, interest on, the Redemption Price of, or the Fundamental Change Purchase
Price for, and any amounts due upon the conversion of, the Securities, as the case may be, and such further amount as is sufficient to cover the costs and expenses of collection, including the reasonable compensation, expenses, disbursements and
advances of the Trustee, its agents and counsel, as well as any other amounts that may be due under Section 7.06 of the Base Indenture. 
 Section 9.10 Trustee May Enforce Claims Without Possession of Securities. All rights of action and claims under this Indenture or the Securities may be prosecuted and enforced by the Trustee
without the possession of any of the Securities or the production thereof in any 

  
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proceeding relating thereto, and any such proceeding instituted by the Trustee shall be brought in its own name as trustee of an express trust, and any recovery of judgment shall, after provision
for the payment of the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, be for the ratable benefit of the Holders in respect of which such judgment has been recovered. 

Section 9.11 Trustee May File Proofs of Claim. The Trustee is authorized to file such proofs of claim and other papers or
documents as may be necessary or advisable to have the claims of the Trustee and the Holders allowed in any judicial proceedings relative to the Company, its creditors or its property and, unless prohibited by law or applicable regulations, will be
entitled to collect, receive and distribute any money or other property payable or deliverable on any such claims, and any custodian in any such judicial proceeding is hereby authorized by each Holder to make such payments to the Trustee, and, in
the event that the Trustee consents to the making of such payments directly to the Holders, to pay to the Trustee any amount due to it for the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, and
any other amounts due the Trustee under Section 7.06 of the Base Indenture. To the extent that the payment of any such compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, and any other amounts due the
Trustee under Section 7.06 of the Base Indenture out of the estate in any such proceeding will be denied for any reason, payment of the same will be secured by a lien on, and is paid out of, any and all distributions, dividends, money,
securities and other properties that the Holders may be entitled to receive in such proceeding, whether in liquidation or under any plan of reorganization or arrangement or otherwise. Nothing herein contained will be deemed to authorize the Trustee
to authorize or consent to, or to accept or to adopt on behalf of any Holder, any plan of reorganization, arrangement, adjustment or composition affecting the Securities or the rights of any Holder, or to authorize the Trustee to vote in respect of
the claim of any Holder in any such proceeding. 
 Section 9.12 Restoration of Rights and Remedies. If the Trustee or any
Holder has instituted any proceeding to enforce any right or remedy under this Indenture and such proceeding has been discontinued or abandoned for any reason, or has been determined adversely to the Trustee or to such Holder, then and in every such
case, subject to any determination in such proceeding, the Company, the Trustee and the Holders shall be restored severally and respectively to their former positions hereunder and thereafter all rights and remedies of the Trustee and the Holders
shall continue as though no such proceeding had been instituted. 
 Section 9.13 Rights and Remedies Cumulative. Except
as otherwise provided with respect to the replacement or payment of mutilated, destroyed, lost or stolen Securities in Section 2.07 of the Base Indenture, no right or remedy herein conferred upon or reserved to the Trustee or to the Holders is
intended to be exclusive of any other right or remedy, and every right and remedy shall, to the extent permitted by law, be cumulative and in addition to every other right and remedy given hereunder or now or hereafter existing at law or in equity
or otherwise. The assertion or employment of any right or remedy hereunder, or otherwise, shall not prevent the concurrent assertion or employment of any other appropriate right or remedy. 

  
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 Section 9.14 Delay or Omission Not a Waiver. No delay or omission of the Trustee or
of any Holder to exercise any right or remedy accruing upon any Event of Default shall impair any such right or remedy or constitute a waiver of any such Event of Default or an acquiescence therein. Every right and remedy given by this Article 9 or
by law to the Trustee or to the Holders may be exercised from time to time and as often as may be deemed expedient by the Trustee (subject to the limitations contained in this Indenture) or by the Holders, as the case may be. 

Section 9.15 Priorities. Subject to Article 5 hereof, if the Trustee collects any money pursuant to this Article 9, it will pay
out the money in the following order: 
 FIRST: to the Trustee, its agents and attorneys for amounts due under Section 7.06
(a) of the Base Indenture, including payment of all compensation, expenses and liabilities incurred, and all advances made, by the Trustee and the costs and expenses of collection; 

SECOND: to the payment of all Senior Indebtedness of the Company if and to the extent required by Article 5; 

THIRD: to the Holders, for any amounts due and unpaid on the principal of, accrued and unpaid interest on, the Redemption Price of, or
the Fundamental Change Purchase Price for, and any cash due upon conversion of, any Security, without preference or priority of any kind, according to such amounts due and payable on all of the Securities; and 

FOURTH: the balance, if any, to the Company or to such other party as a court of competent jurisdiction directs. 

The Trustee may fix a record date and payment date for any payment to the Holders pursuant to this Section 9.15. If the Trustee so
fixes a record date and a payment date, at least 15 calendar days prior to such record date, the Company will deliver to each Holder and the Trustee a written notice, which notice will state such record date, such payment date and the amount of such
payment. 
 Section 9.16 Undertaking for Costs. All parties to this Indenture agree, and each Holder, by such
Holder’s acceptance of a Security, shall be deemed to have agreed, that any court may in its discretion require, in any suit for the enforcement of any right or remedy under this Indenture, or in any suit against the Trustee for any action
taken or omitted by it as Trustee, the filing by any party litigant in such suit of an undertaking to pay the costs of such suit, and that such court may in its discretion assess reasonable costs, including reasonable attorneys’ fees, against
any party litigant in such suit, having due regard to the merits and good faith of the claims or defenses made by such party litigant; provided, however, that the provisions of this Section 9.16 shall not apply to any suit
instituted by the Trustee, to any suit instituted by any Holder, or group of Holders, holding in the aggregate more than 10% in aggregate principal amount of the Securities then Outstanding, or to any suit instituted by any Holder for the
enforcement of the payment of the principal of, accrued and unpaid interest, if any, on, the Redemption Price of, or the Fundamental Change Purchase Price for, any Security on or after the due date expressed or provided for in this Indenture or to
any suit for the enforcement of the right to convert any Security in accordance with the provisions of Article 4 hereof. 

  
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 Section 9.17 Waiver of Stay, Extension and Usury Laws. The Company covenants that, to
the extent that it may lawfully do so, it will not at any time insist upon, plead, or in any manner whatsoever claim or take the benefit or advantage of, any stay, extension or usury law wherever enacted, now or at any time hereafter in force, that
may affect the covenants or the performance of this Indenture; and the Company, to the extent that it may lawfully do so, hereby expressly waives all benefit or advantage of any such law, and covenants that it will not, by resort to any such law,
hinder, delay or impede the execution of any power herein granted to the Trustee, but will instead suffer and permit the execution of every such power as though no such law has been enacted. 

Section 9.18 Notices from the Trustee. Notwithstanding anything to the contrary in the Base Indenture, including Section 7.14
thereof, whenever a Default occurs and is continuing and is actually known to the Trustee, the Trustee must deliver notice of such Default to the Holders within 90 calendar days after the date on which such Default first occurred. Except in the case
of a Default in the payment of the principal of (including the Fundamental Change Purchase Price or the Redemption Price with respect to) or interest on, any Security or of a Default in the payment or delivery, as the case may be, of the
consideration due upon conversion of a Security, the Trustee shall be protected in withholding such notice if and so long as it in good faith determine that the withholding of such notice is in the interests of the Holders. 

Section 9.19 Statements as to Defaults. The Company shall deliver to the Trustee, as soon as possible, and in any event within 30
calendar days after the Company becomes aware of the occurrence of any Default or Event of Default, as applicable, an Officer’s Certificate setting forth the details of such Default or Event of Default, its status and the action that the
Company is taking or proposes to take in respect thereof. Such Officer’s Certificate shall also comply with any additional requirements set forth in Section 13.12 of the Base Indenture, as if such Officer’s Certificate were being
delivered pursuant to Section 13.12 thereof. 
 Section 9.20 Supplementary Interest Notice. If Supplementary
Interest is payable by the Company pursuant to Section 9.04 hereof, the Company shall deliver to the Trustee an Officer’s Certificate to that effect stating (a) the amount of such Supplementary Interest that is payable and
(b) the date on which such Supplementary Interest is payable. Unless and until a Responsible Officer of the Trustee receives at the Corporate Trust Office such a certificate, the Trustee may assume without inquiry that no such Supplementary
Interest is payable. If the Company has paid Supplementary Interest directly to the Persons entitled to it, the Company shall deliver to the Trustee an Officer’s Certificate setting forth the particulars of such payment. 

Section 9.21 Standard of Care. The Trustee will be required, in the exercise of its powers as Trustee, to use the degree of care
that a prudent person would use in the conduct of its own affairs. The Trustee, however, may refuse to follow any direction (x) that conflicts with law or this Indenture, (y) that the Trustee determines is unduly prejudicial to the rights
of any other holder, or (z) that would involve the Trustee in personal liability. Prior to taking any action under this Indenture, the Trustee will receive indemnification satisfactory to it in its sole discretion against all losses and
expenses caused by taking or not taking such action. 

  
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 ARTICLE 10. 
 SATISFACTION AND DISCHARGE 
 Section 10.01 Inapplicability of Provisions
of Base Indenture; Satisfaction and Discharge of the Indenture. The satisfaction and discharge provisions set forth in this Article 10 shall, with respect to the Securities, supersede the entirety of Article 11 of the Base Indenture, and all
references in the Base Indenture to Article 11 thereof and the provisions relating to satisfaction and discharge therein, as the case may be, shall, with respect to the Securities, be deemed to be references to this Article 10 and the satisfaction
and discharge provisions set forth in this Article 10, respectively. 
 When (a) the Company shall deliver to the Registrar
for cancellation all Outstanding Securities theretofore authenticated (other than any Securities that have been destroyed, lost or stolen and in lieu of or in substitution for which other Securities shall have been authenticated and delivered) and
not theretofore canceled, or (b) all the Outstanding Securities not theretofore canceled or delivered to the Trustee for cancellation shall have become due and payable (whether on the Maturity Date, on any Redemption Date, on any Fundamental
Change Purchase Date, upon conversion or otherwise) and the Company shall deposit with the Trustee, in trust, or deliver to the Holders, as applicable, an amount of cash, number of shares of Common Stock or the combination of cash and shares of
Common Stock, as the case may be (solely to settle amounts due with respect to outstanding conversions, if applicable), sufficient (after giving effect to the provisions of Article 5) to pay all amounts due on all of such Securities (other than any
Securities that shall have been mutilated, destroyed, lost or stolen and in lieu of or in substitution for which other Securities shall have been authenticated and delivered) not theretofore canceled or delivered to the Trustee for cancellation,
including principal and interest due, accompanied, except in the event the Securities are due and payable solely in cash at the Maturity Date or upon an earlier Fundamental Change Purchase Date or Redemption Date, by a verification report as to the
sufficiency of the deposited amount from an independent certified accountant or other financial professional reasonably satisfactory to the Trustee, and if the Company shall also pay or cause to be paid all other sums payable hereunder by the
Company, then this Indenture shall cease to be of further effect (except as to (i) rights hereunder of Holders to receive all amounts owing upon the Securities and the other rights, duties and obligations of Holders, as beneficiaries hereof
with respect to the amounts, if any, so deposited with the Trustee and (ii) the rights, obligations and immunities of the Trustee hereunder), and the Trustee, on written demand of the Company accompanied by an Officer’s Certificate and an
Opinion of Counsel and at the cost and expense of the Company, shall execute proper instruments acknowledging satisfaction and discharge of this Indenture; the Company, however, hereby agrees to reimburse the Trustee for any costs or expenses
thereafter reasonably and properly incurred by the Trustee, including the fees and expenses of its counsel, and to compensate the Trustee for any services thereafter reasonably and properly rendered by the Trustee in connection with this Indenture
or the Securities. 
 Section 10.02 Deposited Monies to Be Held in Trust by Trustee. Subject to Article 5 and
Section 10.04 hereof, all monies and shares of Common Stock, as the case may be, deposited with the Trustee pursuant to Section 10.01 hereof shall be held in trust for the sole benefit of the Holders of the Securities, and such monies and
shares of Common Stock shall be applied by the Trustee to the payment, notwithstanding the provisions of Article 5 hereof, either directly or 

  
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through any Paying Agent (including the Company if acting as its own Paying Agent), to the Holders of the particular Securities for the payment, settlement or redemption of which such monies or
shares of Common Stock, or both, as the case may be, have been deposited with the Trustee, of all sums or amounts due and to become due thereon for principal and interest, if any. 

Section 10.03 Paying Agent to Repay Monies Held. Upon the satisfaction and discharge of this Indenture, all monies and shares of
Common Stock, as the case may be, then held by any Paying Agent (if other than the Trustee) shall, upon written request of the Company, be repaid to it or paid to the Trustee, and thereupon such Paying Agent shall be released from all further
liability with respect to such monies and shares of Common Stock, or both, as the case may be. 
 Section 10.04 Return of
Unclaimed Monies. Subject to the requirements of applicable law, any monies and shares of Common Stock deposited with or paid to the Trustee for payment of the principal of or interest, if any, on the Securities and not applied but remaining
unclaimed by the Holders of the Securities for two years after the date upon which the principal of or interest, if any, on such Securities, as the case may be, shall have become due and payable, shall be repaid to the Company by the Trustee on
demand, and all liability of the Trustee shall thereupon cease with respect to such monies and shares of Common Stock; and the Holder shall thereafter look only to the Company for any payment or delivery that such Holder may be entitled to collect
unless an applicable abandoned property law designates another Person. 
 Section 10.05 Reinstatement. If the Trustee or
the Paying Agent is unable to apply any money or shares of Common Stock, or both, as the case may be, in accordance with Section 10.02 by reason of any order or judgment of any court or governmental authority enjoining, restraining or otherwise
prohibiting such application, the Company’s obligations under the Indenture and the Securities shall be revived and reinstated as though no deposit had occurred pursuant to Section 10.01 until such time as the Trustee or the Paying Agent
is permitted to apply all such money and shares of Common Stock in accordance with Section 10.02; provided, however, that if the Company makes any payment of interest on, principal of or payment or delivery in respect of any Security
following the reinstatement of its obligations, the Company shall be subrogated to the rights of the Holders of such Securities to receive such payment from the money or shares of Common Stock, if any, held by the Trustee or Paying Agent.

 ARTICLE 11. 
 SUPPLEMENTAL INDENTURES 
 Section 11.01 Supplemental Indentures Without
Consent of Holders. Section 9.01 of the Base Indenture shall not apply with respect to the Securities, and this Section 11.01 shall replace Section 9.01 of the Base Indenture in its entirety, and all references in the Base
Indenture to Section 9.01 thereof shall, with respect to the Securities, be deemed to be references to this Section 11.01. 
 Without the consent of any Holder, the Company and the Trustee, at any time and from time to time, may enter into one or more indentures supplemental hereto, in form satisfactory to the Trustee, for any
of the following purposes: 

  
 68 

 (a) to cure any ambiguity, omission, defect or inconsistency in this Indenture or the
Securities, including to eliminate any conflict with the terms of the Trust Indenture Act as evidenced in an Officer’s Certificate; 
 (b) to conform the terms of this Indenture or the Securities to the description thereof in the Preliminary Prospectus Supplement, as supplemented by the Issuer Free Writing Prospectus Term Sheet related
to the offering of the Securities; 
 (c) to provide for the conversion of the Securities into Reference Property and effect any
other changes to the terms of the Securities required under this Indenture in connection therewith; 
 (d) to evidence the
succession by a Successor Company and to provide for the assumption by a Successor Company of the Company’s obligations under the Indenture; 
 (e) to add guarantees with respect to the Securities; 
 (f) to secure the
Securities; 
 (g) to add to the Company’s covenants, restrictions, conditions or provisions such new covenants,
restrictions, conditions or provisions for the benefit of the Holders of all or any series of debt securities, to make the occurrence, or the occurrence and the continuance, of a Default in any such additional covenants, restrictions, conditions or
provisions an Event of Default or surrender any right or power conferred upon the Company in the Indenture; 
 (h) to make any
other change that does not adversely affect the rights of any Holder (other than a Holder that consents to such change); 
 (i)
to evidence and provide for the acceptance of appointment of a successor Trustee; 
 (j) to comply with the Applicable
Procedures of the Depositary; or 
 (k) to comply with any requirement of the Commission in connection with the qualification of
the Indenture under the Trust Indenture Act. 
 Section 11.02 Supplemental Indentures With Consent of Holders.
Section 9.02 of the Base Indenture shall not apply with respect to the Securities, and this Section 11.02 shall replace Section 9.02 of the Base Indenture in its entirety. 

This Indenture or the Securities may be amended with the consent of the Holders of at least a majority of the principal amount of then
outstanding Securities (including consents obtained in connection with a purchase of, or tender or exchange offer for, Securities) by act of said Holders delivered to the Company and the Trustee, the Company and the Trustee may enter into an
indenture or indentures supplemental hereto for the purpose of amending the Indenture or the Securities; provided, however, that no such supplemental indenture shall, without the consent of the Holder of each Outstanding Security
affected thereby: 

  
 69 

 (a) reduce the percentage in aggregate principal amount of Securities Outstanding necessary
to waive any past Default or Event of Default; 
 (b) reduce the rate of interest on any Security or change the time for payment
of interest on any Security; 
 (c) reduce the principal of any Security or change the Maturity Date; 

(d) change the place or currency of payment on any Security; 
 (e) make any change that impairs or adversely affects the conversion rights of any Securities; 
 (f) reduce the Redemption Price or the Fundamental Change Purchase Price of any Security or amend or modify in any manner adverse to the rights of the Holders the Company’s obligation to pay the
Redemption Price or the Fundamental Change Purchase Price, whether through an amendment or waiver of provisions in the covenants, definitions related thereto or otherwise; 
 (g) impair the right of any Holder of Securities to receive payment of principal of, and interest, if any, on, its Securities, or the right to receive payment or delivery, as the case may be, of the
consideration due upon conversion of its Securities on or after the due dates therefor or to institute suit for the enforcement of any such payment or delivery, as the case may be, with respect to such Holder’s Securities; 

(h) change the ranking of the Securities in any manner adverse to the Holders; 

(i) make any change to the provisions of this Article 11 or in the waiver provisions of the Indenture that requires each Holder’s
consent to modify, amend or waive; or 
 (j) make any change to the provisions of Article 6 hereof or provisions of the Pledge
and Escrow Agreement related to the Pledged Collateral, in each case if such change would adversely affect the right of the Holders. 
 It shall not be necessary for any act or consent of Holders under this Article 11 to approve the particular form of any proposed supplemental indenture or amendment hereto, but it shall be sufficient if
such act, consent or amendment shall approve the substance thereof. The Company may, but shall not be obligated to, fix a record date for the purpose of determining the Persons entitled to consent to any amendment or indenture supplemental hereto.
If a record date is fixed, the Holders on such record date, or their duly designated proxies, and only such Persons, shall be entitled to consent to such supplemental indenture or amendment hereto, whether or not such Holders remain Holders after
such record date; provided that, unless such consent shall have become effective by virtue of the requisite percentage having been obtained prior to the date which is 90 calendar days after such record date, any such consent previously given
shall automatically and without further action by any Holder be cancelled and of no further effect. 
 Section 11.03 Notice
of Amendment or Supplement. After an amendment or supplement under this Article 11 becomes effective, the Company shall mail to the Holders a notice briefly 

  
 70 

 
describing such amendment or supplement. However, the failure to give such notice to all the Holders, or any defect in the notice, shall not impair or affect the validity of the amendment or
supplement. 
 ARTICLE 12. 
 SUCCESSOR COMPANY 
 Section 12.01 Consolidation, Merger and Sale of
Assets. The successor company provisions set forth in this Article 12 shall, with respect to the Securities, supersede the entirety of Article 10 of the Base Indenture, with the provisions of Section 12.02 of this Supplemental Indenture
superseding the provisions of Section 10.01 of the Base Indenture and the provisions of Section 12.03 of this Supplemental Indenture superseding Section 10.02 of the Base Indenture. In addition, each reference in the Base Indenture to
Section 10.01 of the Base Indenture will, with respect to the Securities, be deemed to be a reference to Section 12.02 of this Supplemental Indenture. 
 Section 12.02 Company May Consolidate, Etc. on Certain Terms. The Company shall not consolidate with or merge with or into, or convey, transfer or lease its properties and assets substantially as
an entirety to, another Person (a “Merger Transaction”), unless: 
 (a) the resulting, surviving or transferee
Person (the “Successor Company”), if not the Company, is a Person organized and existing under the laws of the United States of America, any State thereof or the District of Columbia, and such Person, if not the Company, expressly
assumes, by supplemental indenture all of the obligations of the Company under the Securities and this Indenture as applicable to the Securities; and 
 (b) immediately after giving effect to such transaction, no Event of Default shall have occurred and be continuing under this Indenture. 

For the avoidance of doubt, the Trustee shall have no duty or obligation to determine whether Sections 12.02(a) and (b) have been
satisfied in the event of such consolidation, merger, transfer or lease. 
 Section 12.03 Successor Corporation to Be
Substituted. In case of any such Merger Transaction, the Successor Company shall succeed to and be substituted for, and may exercise every right and power of, the Company under this Indenture, with the same effect as if it had been named as the
Company herein as the party of the first part; and the Company shall be discharged from its obligations under the Securities and this Indenture, except in the case of any lease of all or substantially all of the Company’s assets. 

ARTICLE 13. 

MISCELLANEOUS 
 Section 13.01 [Reserved.] 
 Section 13.02 Effect on Successors and Assigns.
All agreements of the Company, the Trustee, the Registrar, the Paying Agent and the Conversion Agent in this Indenture and the Securities will bind their respective successors. 

  
 71 

 Section 13.03 Governing Law; Waiver of Jury Trial. 

(a) Section 13.05 of the Base Indenture shall not apply with respect to the Securities and this Section 13.03 shall replace
Section 13.05 of the Base Indenture in its entirety. 
 (b) This Supplemental Indenture and the Securities shall be deemed
to be contracts made under the law of the State of New York and for all purposes shall be governed by and construed in accordance with the law of said State (except to the extent that the Trust Indenture Act is applicable) without regards to
conflict of law principles thereof. Each party hereto and each Holder of Securities by acceptance thereof, hereby waives, to the fullest extent permitted by applicable law, any right it may have to a trial by jury in respect of any litigation
directly or indirectly arising out of, under or in connection with this Indenture. 
 Section 13.04 No Security Interest
Created. Except as set forth in Article 7 hereof, nothing in this Indenture or in the Securities, expressed or implied, shall be construed to constitute a security interest under the Uniform Commercial Code or similar legislation, as now or
hereafter enacted and in effect, in any jurisdiction. 
 Section 13.05 Trust Indenture Act. If any provision hereof
limits, qualifies or conflicts with a provision of the Trust Indenture Act that is required under such Act to be a part of and govern this Indenture, the latter provision shall control. If any provision of this Indenture modifies or excludes any
provision of the Trust Indenture Act that may be so modified or excluded, the latter provision shall be deemed to apply to this Indenture as so modified or to be excluded, as the case may be. 

Section 13.06 Benefits of Supplemental Indenture. Nothing in this Supplemental Indenture or in the Securities, expressed or
implied, will give to any Person, other than the parties hereto, any Paying Agent, any Conversion Agent, any authenticating agent, any Registrar or their successors hereunder or the Holders of the Securities, any benefit or any legal or equitable
right, remedy or claim under this Supplemental Indenture. 
 Section 13.07 Calculations. Except as otherwise provided in
this Indenture, the Company shall be responsible for making all calculations called for under the Securities. None of the Trustee, Conversion Agent, Registrar, Bid Solicitation Agent or Paying Agent (in each case if different from the Company) shall
have any responsibility for making such calculations, for determining amounts to be paid or for monitoring the market price of the Common Stock or be charged with any knowledge of or have any duties to monitor any measurement period. These
calculations include determinations of the Last Reported Sale Prices of the Common Stock, accrued interest payable on the Securities, the Daily VWAP, the Daily Conversion Value, the Daily Settlement Amount and the Conversion Rate. The Company shall
make all these calculations in good faith and, absent manifest error, the Company’s calculations shall be final and binding on Holders of Securities. The Company shall provide a schedule of its calculations to each of the Trustee and the
Conversion Agent, and each of the Trustee and Conversion Agent is entitled to rely conclusively upon the accuracy of the Company’s calculations without independent verification. The Trustee will forward the Company’s calculations to any
Holder upon the request of that Holder at the sole cost and expense of the Company. 

  
 72 

 Whenever the Company is required to calculate the Conversion Rate, the
Company will do so to the 1/10,000th of a share of Common
Stock. 
 Section 13.08 Execution in Counterparts. This Supplemental Indenture may be executed in any number of
counterparts, each of which shall be an original, but such counterparts shall together constitute but one and the same instrument. Delivery of an executed counterpart of a signature page to this Agreement by facsimile or electronic transmission
shall be effective as delivery of a manually executed counterpart of this Agreement. 
 Section 13.09 Ratification of Base
Indenture. The Base Indenture, as supplemented by this Supplemental Indenture, is in all respects ratified and confirmed, and this Supplemental Indenture shall be deemed part of the Base Indenture in the manner and to the extent herein provided.
For the avoidance of doubt, each of the Company and each Holder of Securities, by its acceptance of such Securities, acknowledges and agrees that all of the rights, privileges, protections, immunities and benefits afforded to the Trustee under the
Base Indenture are deemed to be incorporated herein, and shall be enforceable by the Trustee hereunder, in each of its capacities hereunder as if set forth herein in full. 
 Section 13.10 The Trustee. The recitals in this Supplemental Indenture are made by the Company only and not by the Trustee, and all of the provisions contained in the Base Indenture in respect of
the rights, privileges, immunities, powers and duties of the Trustee shall be applicable in respect of the Securities and of this Supplemental Indenture as fully and with like effect as set forth in full herein. 

[Remainder of the page intentionally left blank] 

  
 73 

 IN WITNESS WHEREOF, the parties hereto have caused this First Supplemental Indenture
to be duly executed as of the day and year first above written. 
  

			
	EXELIXIS, INC.
		
	By:	 	 /s/ Michael M. Morrissey, Ph.D.

		 	Name: Michael M. Morrissey, Ph.D.
		 	Title: President and Chief Executive Officer

 

			
	Attest:
	
	 /s/ James B. Bucher

	Name:	 	James B. Bucher
	Title:	 	Vice President, Corporate Legal Affairs and Secretary

 Exelixis, Inc. – First Supplemental Indenture Signature Page 

 
			
	WELLS FARGO BANK, NATIONAL
ASSOCIATION, as Trustee
		
	By:	 	 /s/ Maddy Hall

		 	Name: Maddy Hall
		 	Title: Vice President

 Exelixis, Inc. – First Supplemental Indenture Signature Page 

 SCHEDULE A 
 The following table sets forth the number of Additional Shares by which the Conversion Rate shall be increased pursuant to Section 4.06 based on the Stock Price and Effective Date set forth below.

  

																																																	
	 	 	Stock Price	 
	Effective Date	 	$ 4.25	 	 	$ 4.50	 	 	$ 4.75	 	 	$ 5.00	 	 	$ 5.31	 	 	$ 5.75	 	 	$ 6.25	 	 	$ 6.91	 	 	$ 8.00	 	 	$ 9.00	 	 	$ 10.00	 	 	$ 12.00	 
	 August 14, 2012
	 	 	47.0588	  	 	 	45.6194	  	 	 	43.5052	  	 	 	39.0592	  	 	 	33.8266	  	 	 	28.0410	  	 	 	23.0131	  	 	 	17.7350	  	 	 	11.4029	  	 	 	7.6519	  	 	 	5.1337	  	 	 	2.2360	  
	 August 15, 2013
	 	 	47.0588	  	 	 	44.3130	  	 	 	39.0886	  	 	 	34.3736	  	 	 	29.4476	  	 	 	24.0755	  	 	 	19.4717	  	 	 	14.6907	  	 	 	9.0614	  	 	 	5.8546	  	 	 	3.7248	  	 	 	1.4156	  
	 August 15, 2014
	 	 	47.0588	  	 	 	40.0921	  	 	 	34.6279	  	 	 	29.8685	  	 	 	25.6127	  	 	 	20.2135	  	 	 	15.6784	  	 	 	11.4514	  	 	 	6.6579	  	 	 	4.0294	  	 	 	2.3284	  	 	 	0.7141	  
	 August 15, 2015
	 	 	47.0588	  	 	 	35.6583	  	 	 	30.0131	  	 	 	25.6521	  	 	 	20.5353	  	 	 	15.3787	  	 	 	11.2339	  	 	 	7.6949	  	 	 	3.9576	  	 	 	1.9690	  	 	 	1.0258	  	 	 	0.1780	  
	 August 15, 2016
	 	 	47.0588	  	 	 	33.4583	  	 	 	26.5719	  	 	 	20.6924	  	 	 	15.1334	  	 	 	8.4774	  	 	 	3.5861	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  
	 August 15, 2017
	 	 	47.0588	  	 	 	35.4874	  	 	 	28.3545	  	 	 	22.2020	  	 	 	15.7784	  	 	 	9.3156	  	 	 	3.6909	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  
	 August 15, 2018
	 	 	47.0588	  	 	 	38.2024	  	 	 	30.3349	  	 	 	23.7891	  	 	 	16.9758	  	 	 	9.6966	  	 	 	4.0006	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  
	 August 15, 2019
	 	 	47.0588	  	 	 	33.9869	  	 	 	22.2910	  	 	 	11.7647	  	 	 	0.0886	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  	 	 	0.0000	  

 EXHIBIT A 
 [FORM OF FACE OF SECURITY] 
 [For Global Securities, include the following legend:

 UNLESS THIS CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION
(“DTC”), TO THE COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF
DTC (AND ANY PAYMENT IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE
REGISTERED OWNER HEREOF, CEDE & CO. 
  

			
	No.:	  	[                    ]
	CUSIP:	  	30161Q AC8
	ISIN:	  	US30161QAC87

 Principal Amount $[            ]

 [as revised by the Schedule of Increases 

and Decreases in the Global Security attached hereto]1 
 Exelixis, Inc. 

4.25% Convertible Senior Subordinated Notes due 2019 
 Exelixis, Inc., a Delaware corporation, promises to pay to [            ] [include “Cede & Co.” for
Global Security] or registered assigns, the principal amount of $[            ] on August 15, 2019 (the “Maturity Date”) and to pay interest
hereon as set forth in the Indenture in the manner, at the rates and to the Persons set forth therein. 
  

			
	Interest Payment Dates:	  	February 15 and August 15.
		
	Regular Record Dates:	  	February 1 and August 1.

 Additional provisions of this Security are set forth on the other side of this Security. 

 

	1 	Include for Global Securities only. 

  
 A-1

 IN WITNESS WHEREOF, EXELIXIS, INC. has caused this instrument to be signed manually or by
facsimile by two of its duly authorized officers. 

Dated:                    

  

			
	EXELIXIS, INC.
		
	By:	 	  

		 	Name:
		 	Title:
		 	

  

			
	Attest:
	
	  

 [Trustee’s Certificate of Authentication Follows] 

  
 A-2

 TRUSTEE’S CERTIFICATE OF AUTHENTICATION 

Wells Fargo Bank, National Association, as Trustee, certifies that this is one of the Securities referred to in the
within-mentioned Indenture. 
 Dated: 

WELLS FARGO BANK, 
 NATIONAL ASSOCIATION,

 as Trustee 
  

			
	By:	 	  

	  Authorized Signatory

  
 A-3

 [FORM OF REVERSE OF NOTE] 

EXELIXIS, INC. 

4.25% Convertible Senior Subordinated Notes due 2019 
 This Security is one of a duly authorized issue of securities of the Company (herein called the “Securities”), issued under an Indenture dated as of August 14, 2012 (herein called
the “Base Indenture”), and as further supplemented by the First Supplemental Indenture, dated as of August 14, 2012 (herein called the “Supplemental Indenture” and the Base Indenture, as supplemented by the
Supplemental Indenture, the “Indenture”), by and between the Company and Wells Fargo Bank, National Association, herein called the “Trustee”, and reference is hereby made to the Indenture for a statement of the
respective rights, limitations of rights, duties and immunities thereunder of the Company, the Trustee and the Holders of the Securities and of the terms upon which the Securities are, and are to be, authenticated and delivered. 

This Security (other than the portion representing the Securities the Company is required to repurchase as provided under Article 3 of
the Supplemental Indenture) is subject to redemption at the option of the Company on or after August 15, 2016, at the Redemption Price; provided that the Last Reported Sale Price of the Company’s Common Stock for 20 or more Trading Days in
a period of 30 consecutive Trading Days immediately prior to the date of the Redemption Notice exceeds 130% of the applicable Conversion Price in effect on each such Trading Day. The redemption price will equal 100% of the principal amount of the
Securities being redeemed, plus accrued and unpaid interest, if any, to, but excluding, the Redemption Date. Any Securities redeemed by the Company will be paid for in cash. 
 As provided in and subject to the provisions of the Indenture, upon the occurrence of a Fundamental Change, the Holder of this Security will have the right, at such Holder’s option, to require the
Company to purchase this Security, or any portion of this Security such that the principal amount of this Security that is not purchased equals $1,000 or an integral multiple of $1,000 in excess thereof, on the Fundamental Change Purchase Date at a
price equal to the Fundamental Change Purchase Price for such Fundamental Change Purchase Date. 
 This Security does not
benefit from a sinking fund. 
 As provided in and subject to the provisions of the Indenture, the Holder hereof has the right,
at its option (i) during certain periods and upon the occurrence of certain conditions specified in the Indenture, prior to the Close of Business on the Business Day immediately preceding May 15, 2019, and (ii) on or after
May 15, 2019, at any time prior to the Close of Business on the second Scheduled Trading Day immediately preceding the Maturity Date, to convert this Security or a portion of this Security such that the principal amount of this Security that is
not converted equals $1,000 or an integral multiple of $1,000 in excess thereof into an amount of cash, a number of shares of Common Stock or a combination of cash and shares of Common Stock, as the case may be, determined in accordance with Article
4 of the Supplemental Indenture. 
 As provided in and subject to the provisions of the Indenture, the Company will make all
payments in respect of the Redemption Price of, the Fundamental Change Purchase Price for, 

  
 A-4

 
and the principal amount of, this Security to the Holder that surrenders this Security to the Paying Agent to collect such payments in respect of this Security. The Company will pay cash amounts
in money of the United States that at the time of payment is legal tender for payment of public and private debts. 
 Each
Holder by accepting a Security agrees that the Indebtedness evidenced by the Securities (other than with respect to Obligations of the Securities that are secured by a pledge of the Escrow Account in accordance with Article 7 of the Supplemental
Indenture and the assets therein pursuant to the Pledge and Escrow Agreement, solely to the extent of the assets therein and proceeds thereof) is subordinated in right of payment, to the extent and in the manner provided in this Article 5 of the
Supplemental Indenture, to the prior payment in full of all Senior Indebtedness (whether outstanding on the date of the Supplemental Indenture or hereafter created, incurred, assumed or guaranteed), and that the subordination is for the benefit of
the holders of Senior Indebtedness. 
 As provided in and subject to the provisions of the Indenture, the Company’s
obligations under this Security are secured in part until August 15, 2015 by a pledge of an Escrow Account and the assets therein pursuant to a Pledge and Escrow Agreement. The Escrow Account will contain an amount of Pledged Collateral
sufficient to fund, when due, the total aggregate amount of the first six scheduled semi-annual interest payments on the Security, excluding additional interest, if any. 
 The Indenture permits, with certain exceptions as therein provided, the amendment thereof and the modification of the rights and obligations of the Company and the rights of the Holders of the Securities
to be effected under the Indenture at any time by the Company and the Trustee with the consent of the Holders of a majority in principal amount of the Securities at the time Outstanding. The Indenture also contains provisions permitting the Holders
of specified percentages in principal amount of the Securities at the time Outstanding, on behalf of the Holders of all Securities, to waive compliance by the Company with certain provisions of the Indenture and certain past Defaults under the
Indenture and their consequences. Any such consent or waiver by the Holder of this Security shall be conclusive and binding upon such Holder and upon all future Holders of this Security and of any Security issued upon the registration of transfer
hereof or in exchange herefor or in lieu hereof, whether or not notation of such consent or waiver is made upon this Security. 

As provided in and subject to the provisions of the Indenture, the Holder of this Security shall not have the right to institute any
proceeding with respect to the Indenture, or for the appointment of a receiver or trustee, or for any other remedy thereunder, unless such Holder shall have previously given the Trustee written notice of a continuing Event of Default with respect to
the Security, the Holders of not less than 25% in principal amount of the Securities at the time Outstanding shall have made written request to the Trustee to institute proceedings in respect of such Event of Default as Trustee and offered the
Trustee reasonable indemnity, and the Trustee shall not have received from the Holders of a majority in principal amount of Securities at the time Outstanding a direction inconsistent with such request, and shall have failed to institute any such
proceeding, for 60 calendar days after receipt of such notice, request and offer of indemnity. The foregoing shall not apply to any suit instituted by the Holder of this 

  
 A-5

 
Security for the enforcement of any payment of principal hereof or any premium or interest hereon on or after the respective due dates expressed herein. 

No reference herein to the Indenture and no provision of this Security or of the Indenture shall alter or impair the obligation of the
Company, which is absolute and unconditional, to pay or deliver, as the case may be, the principal of (including the Redemption Price and the Fundamental Change Purchase Price), interest on and all amounts of consideration due upon conversion of,
this Security at the time, place and rate, and in the coin and currency, herein prescribed. 
 As provided in the Indenture, the
transfer of this Security is registrable in the Register, upon surrender of this Security for registration of transfer at the office or agency of the Company in any place where the principal of and interest on this Security are payable, duly
endorsed by, or accompanied by a written instrument of transfer in form satisfactory to the Company and the Registrar duly executed by, the Holder hereof or its attorney duly authorized in writing, and thereupon one or more new Securities of this
series and of like tenor, of authorized denominations and for the same aggregate principal amount, will be issued to the designated transferee or transferees. 
 The Securities are issuable only in registered form without coupons in denominations of $1,000 and integral multiples of $1,000 in excess thereof. As provided in the Indenture, the Securities are
exchangeable for a like aggregate principal amount of Securities and of like tenor of a different authorized denomination, as requested by the Holder surrendering the same. 
 Prior to due presentment of this Security for registration of transfer, the Company, the Trustee and any agent of the Company or Trustee may treat the Person in whose name the Security is registered as
the owner and holder hereof for all purposes, whether or not this Security be overdue, and neither the Company, the Trustee nor any such agent shall be affected by notice to the contrary. 

No service charge shall be made for any such registration of transfer or exchange, but the Company may require payment of a sum
sufficient to cover any tax or other governmental charge payable in connection therewith. 
 All defined terms used in this
Security that are defined in the Indenture shall have the meanings assigned to them in the Indenture. If any provision of this Security limits, qualifies or conflicts with a provision of the Indenture, such provision of the Indenture shall control.

  
 A-6

 ABBREVIATIONS 
 The following abbreviations, when used in the inscription of the face of this Security, shall be construed as though they were written out in full 

 

							
	TEN COM - as tenants in common	 	 UNIF GIFT MIN ACT
	  	Custodian                         	 	
		 	(Cust)	  		 	
	TEN ENT - as tenants by the entireties	 	  
	  		 	
		 	(Minor)	  		 	
	JT TEN - as joint tenants with right of Survivorship and not as tenants in common	 	Uniform Gifts to Minors Act            	  	  
	 	(State)

 Additional abbreviations may also be used though not in the above list. 

  
 A-7

 ANNEX A 
 [Include for Global Security] 
 SCHEDULE OF INCREASES AND DECREASES
OF GLOBAL SECURITY 
 Initial principal amount of Global Security: $287,500,000 

 

									
	 Date
	 	 Amount of Increase

in principal

amount of Global
 Security
	 	 Amount of

Decrease in

principal amount
 of Global Security
	  	Principal amount
of Global
Security
after Increase or
Decrease	  	Notation by
Registrar or
Security Custodian
		 		 		  		  	
		 		 		  		  	
		 		 		  		  	

  
 A-8

 ATTACHMENT 1 
 [FORM OF NOTICE OF CONVERSION]’ 
 4.25% Convertible Senior Subordinated Notes
due 2019 
 To: Exelixis, Inc. 
 The
undersigned owner of this Security hereby irrevocably exercises the option to convert this Security, or a portion hereof (which is such that the principal amount of the portion of this Security that will not be converted equals $1,000 or an integral
multiple of $1,000 in excess thereof) below designated, into an amount of cash, number of shares of Common Stock or a combination of cash and shares of Common Stock, as the case may be, in accordance with the terms of the Indenture referred to in
this Security, and directs that any cash payable and any shares of Common Stock issuable and deliverable upon conversion, together with any Securities representing any unconverted principal amount hereof, be paid and/or issued and/or delivered, as
the case may be, to the registered Holder hereof unless a different name is indicated below. 
 Subject to certain exceptions set forth in the
Indenture, if this notice is being delivered on a date after the Close of Business on a Regular Record Date and prior to the Open of Business on the Interest Payment Date corresponding to such Regular Record Date, this notice must be accompanied by
payment of an amount equal to the interest payable on such Interest Payment Date on the principal amount of this Security to be converted. If any shares of Common Stock are to be issued in the name of a Person other than the undersigned, the
undersigned will pay all transfer taxes payable with respect to such issuance and transfer as set forth in the Indenture. 
 Principal amount to
be converted (in an integral multiple of $1,000, if less than all): 

			
		 	  

		 	  

		 	Signature(s)
		
		 	Signature(s) must be guaranteed by an institution which is a member of one of the following recognized signature Guarantee Programs:
		
		 	(i) The Securities Transfer Agent Medallion Program (STAMP); (ii) The New York Stock Exchange Medallion Program (MNSP); (iii) The Stock Exchange Medallion Program
(SEMP) or (iv) another guarantee program acceptable to the Trustee.
		 	  

		 	  

		 	Signature Guarantee

  

  
 A-9

 Fill in for registration of any shares of Common Stock and Securities if to be issued otherwise than to the
registered Holder. 
  

			
	  
	 	
	(Name)	 	
		
	  
	 	
	(Address)	 	
		
	 Please print Name and Address

(including zip code number)
	 	
		
	 Social Security or other Taxpayer
 Identifying Number                     
	 	

  
 A-10

 ATTACHMENT 2 
 [FORM OF FUNDAMENTAL CHANGE PURCHASE NOTICE] 
 4.25% Convertible Senior Subordinated Notes due
2019 
 To: Exelixis, Inc. 
 The
undersigned registered owner of this Security hereby acknowledges receipt of a notice from Exelixis, Inc. (the “Company”) as to the occurrence of a Fundamental Change with respect to the Company and specifying the Fundamental Change
Purchase Date and requests and instructs the Company to pay to the registered holder hereof in accordance with the applicable provisions of the Indenture referred to in this Security (i) the entire principal amount of this Security, or the
portion thereof (that is such that the portion not to be purchased has a principal amount equal to $1,000 or an integral multiple of $1,000 in excess thereof) below designated, and (ii) if such Fundamental Change Purchase Date does not occur
during the period after a Regular Record Date and on or prior to the Interest Payment Date corresponding to such Regular Record Date, accrued and unpaid interest, if any, thereon to, but excluding, such Fundamental Change Purchase Date. 

In the case of certificated Securities, the certificate numbers of the Securities to be purchased are as set forth below: 

Dated:                      

 

			
		 	Signature(s)
		
		 	  

		 	 Social Security or Other Taxpayer Identification Number

 
 principal amount to be repaid (if less than all):

$            ,000

		
		 	NOTICE: The signature on the Fundamental Change Purchase Notice must correspond with the name as written upon the face of the Security in every particular without alteration or
enlargement or any change whatever.

  
 A-11

 ATTACHMENT 3 
 [FORM OF ASSIGNMENT AND TRANSFER] 
 4.25% Convertible Senior Subordinated Notes due 2019

 For value received
                                         hereby
sell(s), assign(s) and transfer(s) unto
                                        (Please
insert social security or Taxpayer Identification Number of assignee) the within Security, and hereby irrevocably constitutes and appoints
                                        to
transfer the said Security on the books of the Company, with full power of substitution in the premises. 

			
		
		 	  

		
		 	  

		 	Signature(s)
		
		 	Signature(s) must be guaranteed by an institution which is a member of one of the following recognized signature Guarantee Programs:
		
		 	(i) The Securities Transfer Agent Medallion Program (STAMP); (ii) The New York Stock Exchange Medallion Program (MNSP); (iii) The Stock Exchange Medallion Program
(SEMP) or (iv) another guarantee

  
 A-12

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