Document:

<PAGE>   1

                                                                    EXHIBIT 10.2

                                January 10, 2001

Douglas S. Harrington, M.D.
c/o ChromaVision Medical Systems, Inc.
33171 Paseo Cerveza
San Juan Capistrano, CA  92675

Dear Doug,

         In order to provide a further inducement for you to remain in the
employ of ChromaVision Medical Systems, Inc. (the "Company"), this letter will
supplement the letter agreement between you and the Company dated as of December
30, 1996, a copy of which is attached.

         The supplementary provisions are as follows:

         1. In the event your employment is terminated by the Company without
cause or you terminate your employment for good reason, the Company will do each
of the following (subject to Section 3):

                  (a) continue to pay your salary as a severance benefit for a
         period of two years from the date of termination of your employment at
         the rate in effect immediately prior to such termination, with payment
         to be made to you on the dates such salary would have been paid if your
         employment had not been terminated;

                  (b) pay you a pro-rated portion of your bonus for the year of
         termination (but only if, at the date of termination of employment, the
         performance criteria for earning the bonus were being met to date in
         the judgment of the Compensation Committee of the Board of Directors),
         with payment to be made to you promptly after termination of your
         employment;

                   (c) continue your health insurance for you and your family
         for two years after the termination of your employment (including any
         period as may be required by law), except that such health insurance
         will be discontinued if you become re-employed and are eligible for
         comparable or better health insurance benefits from your new employer
         and, if the Company's plan will not permit such continuation of your
         insurance, the Company will provide comparable insurance to the extent
         all insureds are insurable and such insurance can be obtained at
         reasonable cost;

<PAGE>   2

                  (d) continue providing you with the automobile contemplated by
         your December 30, 1996 letter agreement for two years after the
         termination of your employment unless you become re-employed and are
         eligible to receive a comparable or better automobile benefit from your
         new employer and

                  (e) continue the exercisability and vesting of your
         outstanding stock options in accordance with their terms for the two
         year period of your salary continuation except to the extent that the
         options terminate in accordance with their terms (or the terms of the
         plan under which they were issued) because of a change of control, sale
         of the Company or other event which causes all options outstanding
         under that plan to terminate.

         You will also be entitled to receive the benefits described above if
you resign as an employee of the Company within the period commencing three
months after, and ending nine months after, a change in control or sale of the
Company (as defined in Section 2 of your December 30, 1996 letter agreement) or
if you are terminated as an employee at any time within three months prior to,
otherwise in anticipation of, or nine months after, any such event. Such
benefits will be in lieu of the benefits provided for in the first paragraph of
Section 2 of your December 30, 1996 letter agreement. In the event both this
paragraph and the preceding paragraph apply to the termination of your
employment, there will be no double-counting of benefits and the benefits will
be limited to those set forth in (a) through (e) above.

         2. You will be considered to have terminated your employment "for good
reason" only if two requirements are met. The first requirement will be met if
you terminate your employment within 18 months after the Company elects a new
Chief Executive Officer of the Company, materially reduces your
responsibilities, compensation or employee benefits or changes the location of
the Company's principal executive office to a location that is more than 50
miles from its current location. The second requirement that must be met is that
you give the Company written notice that you believe you have the right to
terminate your employment for good reason and the Company fails to eliminate the
good reason within 15 days after receipt of the notice.

         3. If any of the benefits to you under this letter would result in the
imposition of any tax imposed by Section 4999 of the Internal Revenue Code of
1986 and the regulations thereunder (or any successor provisions), the benefits
referred to in Sections 2(a) through (d) above shall be reduced to such extent
as is necessary to avoid the imposition of any such tax. That determination
shall be made taking into account all other "parachute payments" (as defined in
Section 280G of the Internal Revenue Code and the regulations thereunder or any
successor provisions) to which you would be entitled, including without
limitation the acceleration of the exercise date of stock options. Such
reductions shall be made first to the bonus payments referred to in Section 1(b)
and thereafter, if necessary, to the salary payments referred to in Section 1(a)
and the other benefits referred to in Section 1(c), (d) and (e), except that no
reduction shall be made in the benefits referred to in Section 1(e) unless you
are notified in writing thereof within 30 days after the termination of your
employment.

                                       2
<PAGE>   3

         4. You will not be required to mitigate the amount of any payment
provided for in this Agreement by seeking other employment or otherwise, nor
shall the amount of any benefit provided for in this Agreement be reduced by any
compensation earned by you as a result of employment by another employer, except
as provided in Section 1 (c) and (d). Notwithstanding the foregoing, in the
event that you are entitled, by operation of any applicable law, to unemployment
compensation benefits or benefits under the Worker Adjustment and Retraining Act
of 1988 (known as the "WARN" Act) in connection with the termination of your
employment in addition to those required to be paid to you under this agreement
or your December 30, 1996 letter agreement, then to the extent permitted by
applicable law governing severance payments or notice of termination of
employment, the Company will be entitled to offset against the amounts payable
hereunder the amounts of any such mandated payments.

         5. By signing this letter you acknowledge that the Company will
continue to treat you as an employee during the period of salary continuance for
purpose of the foregoing benefits. All payments to you under this letter are
subject to such taxes and withholding requirements as may be imposed by
applicable law.

         6. Nothing is this letter changes the "at will" nature of your
employment relationship with the Company.

         7. The provisions of this Letter Agreement supersede and replace the
first paragraph of Section 2 and the last paragraph of Section 4 of your
December 30, 1996 letter agreement, except that the 90 day notice provision in
the last sentence of said Section 2 shall continue to apply in the event you
resign other than for good reason and you are entitled to benefits under the
last paragraph of Section 1 of this letter.

         If this letter correctly sets forth the agreement between you and the
Company, please execute this letter in the place indicated below.

                                          Yours very truly,

                                          Thomas R. Testman,
                                          Chairman of the Compensation Committee
                                          of the Board of Directors

AGREED:

--------------------------------------
Douglas S. Harrington, M.D.

Dated: January __, 2001

                                       3<PAGE>   1

                                                                    EXHIBIT 10.3

                                January 10, 2001

Kevin O'Boyle
c/o ChromaVision Medical Systems, Inc.
33171 Paseo Cerveza
San Juan Capistrano, CA  92675

Dear Kevin,

         In order to provide a further inducement for you to remain in the
employ of ChromaVision Medical Systems, Inc. (the "Company"), this letter will
supplement the letter agreement between you and the Company dated as of November
6, 1996, as amended by a letter dated November 26, 1996, copies of both of which
are attached.

         The supplementary provisions are as follows:

         1. In the event your employment is terminated by the Company without
cause (including as a result of a change in control) or you terminate your
employment for good reason, the Company will do each of the following:

                  (a) continue to pay your salary benefit for a period of one
         year from the date of termination of your employment at the rate in
         effect immediately prior to such termination in return for your
         agreement not to compete with the Company during the one year period,
         with payment to be made to you on the dates such salary would have been
         paid if your employment had not been terminated;

                  (b) continue your health insurance for you and your family for
         one year after the termination of your employment (including any period
         as may be required by law), except that such health insurance will be
         discontinued if you become re-employed and are eligible for comparable
         or better health insurance benefits from your new employer and, if the
         Company's plan will not permit such continuation of your insurance, the
         Company will provide comparable insurance to the extent all insureds
         are insurable and such insurance can be obtained at reasonable cost;
         and

                  (c) allow your outstanding stock options to continue to vest
         and be exercisable in accordance with their terms (including any
         acceleration provided for in your November 6, 1996 letter agreement)
         during the one year period of salary continuation except to the extent
         that the options terminate in accordance with their terms (or the terms
         of the plan under which they were issued) because of a change of
         control or other event which causes all options outstanding under that
         plan to terminate.

<PAGE>   2

         2. The provisions in Exhibit A of your November 6, 1996 letter
agreement with respect to payment of performance contingent sums under incentive
programs (bonuses, commissions etc.) and acceleration of your stock options when
our employment is terminated by the Company for convenience (i.e. other than for
cause, death or disability) shall also apply if you terminate your employment
for good reason.

         3. You will be considered to have terminated your employment "for good
reason" only if any of the following events occurs

                  (a) you terminate your employment within 12 months after the
         Company materially reduces your responsibilities, compensation or
         employee benefits provided that you have given the Company written
         notice of any such reduction and the Company has failed to eliminate
         the good reason within 15 days after receipt of the notice;

                  (b) the Company elects a new President or Chief Operating
         Officer and you terminate your employment by the Company only after the
         expiration of four full calendar months from the date the new President
         or Chief Operating Officer actually begins working for the Company and
         not later than 12 full calendar months after that date; or

                  (c) the location of the Company's principal executive office
         is changed to a location that is more than 50 miles from its current
         location.

         4. By signing this letter you acknowledge that the Company will
continue to treat you as an employee for purposes of paying the benefits under
this letter. All such payments are subject to such taxes and withholding
requirements as may be imposed by applicable law.

         5. Nothing is this letter changes the "at will" nature of your
employment relationship with the Company.

         6. Attachment A to your existing letter agreement dated November 26,
1996 states that in the event of a termination of your employment for
convenience of the Company (i.e. other than for cause, death or disability) 50%
of all granted but not yet vested options would vest and become exercisable
immediately. To determine which options are included in the 50%, the options
would become vested and become exercisable in the order they were granted until
the options have become vested and exercisable for that number of shares equal
to 50% of the total number of shares as to which the options were unvested and
unexercisable before acceleration pursuant to that provision of your November
26, 1996 letter agreement and this paragraph 6.

         7. This letter agreement supersedes your existing letter agreement
dated November 26, 1996 and the third bullet point under "Termination for
Convenience (i.e. Other than for Cause)" in Exhibit A of your existing letter
agreement dated November 6, 1996. Except as provided above, your existing letter
agreement dated November 6,1996 shall remain in full force and effect.

                                       2
<PAGE>   3

         If this letter correctly sets forth the agreement between you and the
Company, please execute this letter in the place indicated below.

                                          Yours very truly,

                                          Douglas S. Harrington, M.D,
                                          Chairman of the Board of Directors and
                                          Chief Executive Officer

AGREED:

--------------------------------
Kevin O'Boyle

Dated: January __, 2001

                                       3

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00023-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00023-of-00352.parquet"}]]