Document:

FIRST
AMENDMENT TO THE CLINICAL TRIAL AGREEMENT

 

This
First Amendment to the Clinical Trial Agreement (“First Amendment”) is made on August 28, 2018 (“Effective
Date”) by and between Cancer Center of Kansas (“Institution”) and Cancer Insight, LLC (“CRO”). CRO
and Institution are herein referred to collectively as “Parties.” Individually, each of CRO and Institution is a “Party.”

 

WHEREAS, the
Parties previously entered into a Clinical Trial Agreement (“Agreement”), with an effective date of April 10,
2018, pertaining to the performance of the clinical study titled and described as “A Phase I/IIa Rollover Study of
the Whole-Cell Vaccine BriaVax in Metastatic or Locally Recurrent Breast Cancer Patients in Combination with Ipilimumab or
Pembrolizumab” (the “Study”);

 

WHEREAS,
the Parties desire to amend the Agreement.

 

NOW,
THEREFORE, in consideration of the mutual promises contained herein, the Parties agree as follows:

 

	 	A.	EXHIBIT
    B BUDGET Section J to the Agreement is hereby amended and replaced in its entirety as follows:

 

	 	i.	Sponsor
    may provide pembrolizumab (KEYTRUDA®, anti-PD-1) and ipilimumab (YERVOY®, anti-CTLA-4), as applicable, to Institution.
    In the event Sponsor is unable to do so, Institution may provide pembrolizumab (KEYTRUDA®, anti-PD-1) and ipilimumab (YERVOY®,
    anti-CTLA-4), as applicable, and invoice Sponsor for the costs of such. The cost of ipilimumab for 5mg/ml 40ml vial is hereby
    listed as $29,691.00, inclusive of Institution’s overhead. The cost of pembrolizumab for 25mg/ml 4ml vial is hereby
    listed as $4,786.00, inclusive of Institution’s overhead.

 

	 	B.	Except
    as expressly modified herein, all other terms, conditions, and provisions of the Agreement shall remain in full force and
    effect.

 

    		Page 1 of 2	 

    	 

    

 

The
authorized representatives of the Parties have signed this First Amendment as set forth below.

 

	Cancer
    Center of Kansas	 	Cancer
    Insight, LLC
	 	             	 	 	            
	By:		 	By:	
	 	 	 	 	 
	Name: 	Shaker
    Dakhil	 	Name: 	Steven
    White
	 	 	 	 	 
	Title:	President	 	Title:	Chief
    Operating Officer
	 	 	 	 	 
	Date:	August
    28, 2018	 	Date:	August
    28, 2018
	 	 	 	 	 
	READ
    AND ACKNOWLEDGED:	 	 	 
	BriaCell
    Therapeutics, LLC	 	 	 
	 	 	 	 	 
	By:	
	 	 	 
	 	 	 	 	 
	Name:	William
    V. Williams	 	 	 
	 	 	 	 	 
	Title:	President
    and CEO	 	 	 
	 	 	 	 	 
	Date:	August
    28, 2018	 	 	 

 

    		Page 2 of 2Accelerated
Clinical Trial Agreement

 

This
Accelerated Clinical Trial (ACTA) Agreement (“Agreement”) is made as of August 31, 2018 (“Effective Date”)
by and between University of Miami (“Institution”), having an address at 1320 S. Dixie Highway, Suite 650, Coral Gables,
FL 33146, and Cancer Insight, LLC, a limited liability company having its principal place of business at 1422 E Grayson, 3rd
Floor, San Antonio, TX 78208 (“CRO”). CRO and Institution are herein referred to collectively as “Parties.”
Individually, each of CRO and Institution is a “Party.”

 

WHEREAS,
CRO has been engaged by BriaCell Therapeutics Corp. (the “Sponsor”) to arrange and administer a multi-center clinical
trial funded by Sponsor to determine the safety and efficacy of Sponsor’s product;

 

WHEREAS,
Sponsor is a for-profit organization that intends to conduct a sponsored multi-center clinical trial, described in 1.1 below,
involving the use of certain diagnostic(s), drug(s), devices(s), or biologic(s) provided by Sponsor and desires that Institution
participate in such clinical trial;

 

WHEREAS,
Institution, Sponsor and CRO have agreed to use the ACTA, to accelerate the process of translating laboratory discoveries
into treatments for patients, to engage communities in clinical research efforts, and to train a new generation of clinical and
translational researchers;

 

WHEREAS,
the Institution has appropriate facilities and personnel with the qualification, training, knowledge, and experience necessary
to conduct such a clinical trial; and

 

WHEREAS,
the Study contemplated by this Agreement is of interest and benefit to Institution, Sponsor and CRO, and will further the
instructional and research objectives of Institution in a manner consistent with its status as a research and health care institution;

 

NOW,
THEREFORE, in consideration for the mutual promises made in this Agreement and for valid consideration, the Parties agree
as follows:

 

 1. Scope of Agreement

 

1.1.
Institution will undertake a sponsored multi-center clinical trial (“Study”) described in the protocol entitled “A
Phase I/Ila Rollover Study of the Whole-Cell Vaccine BriaVaxTM in Metastatic or Locally Recurrent Breast Cancer Patients
in Combination with Ipilimumab or Pembrolizumab” and having a protocol designation of BRI-ROL-001, which is incorporated
herein as Exhibit A (“Protocol”). Institution will use its reasonable efforts to only recruit subjects in accordance
with the Protocol. The Study will be conducted by the Institution under the direction of Carmen Calfa M.D., an employee of Institution
(“Principal Investigator”).

 

1.2.
In the event of any conflict between the terms and conditions of this Agreement and the Protocol or between this Agreement
and any of its Exhibits, the terms and conditions of the Protocol shall control with respect to matters of the clinical
conduct of the Study, and the terms of this Agreement shall control with respect to all other matters.

 

    	 	1	 

     

    

 

1.3.
Unless otherwise agreed to by the Parties, Sponsor and/or CRO will provide to Institution on a timely basis, without charge,
the required quantities of properly-labeled Sponsor drug(s) or biologics(s) (“Study Drug”) and/or device(s)
(“Study Device”) and other materials (e.g., Investigator’s Brochure, handling and storage instructions,
and, if applicable, placebo) necessary for Institution to conduct the Study in accordance with the Protocol. Unless stated
otherwise in writing by Sponsor, all such items are and will remain the sole property of Sponsor until administered or
dispensed to Study subjects during the course of the Study. Receipt, storage, and handling of Study Drug or Study Device will
be in compliance with all applicable laws and regulations, the Protocol, and CRO’s or Sponsor’s
instructions.

 

1.4.
CRO and Institution shall comply with and conduct all aspects of the Study in compliance with all applicable federal, state,
and local laws and regulations, including generally accepted standards of good clinical practice as adopted by current FDA
regulations and statutes and regulations of the U.S. Government relating to exportation of technical data, computer software,
laboratory prototypes, and other commodities as applicable to academic institutions. Institution will only allow individuals
who are appropriately trained and qualified to assist in the conduct of the Study.

 

1.5.
Institution shall obtain IRB approval for this Study and proof thereof shall be provided to CRO. Initiation of the Protocol
and Institution’s obligation to conduct the Study shall not begin until IRB approval is obtained. Institution shall
obtain from each subject, prior to the subject’s participation in the Study, a signed informed consent and necessary
authorization to disclose health information to CRO and/or Sponsor in a form approved in writing by the IRB or a waiver of
consent as directed by the IRB and further provided that the informed consent is consistent with Institution’s
policies.

 

1.6.
Institution shall promptly inform Sponsor of any urgent safety measures as instructed in the Protocol or breaches of the
Protocol of which Institution becomes aware.

 

1.7.
Institution acknowledges CRO’s right to assign or transfer, in whole or in part, with notice to Institution, any of its
rights or obligations under this Agreement to the Sponsor or Sponsor’s designate.

 

2.
Payments

 

Sponsor
will provide financial support for the Study and will provide such funds to CRO who will pay Institution in accordance with the
budget attached as Exhibit B (“Budget”) on a prorated basis, according to the actual work completed and any
non-cancelable obligated expenses, for subjects who are enrolled into the Study. The Parties acknowledge that the Budget amounts
represent an equitable exchange for the conduct of the Study in light of the professional time and expenses required for the performance
of the Study.

 

In
addition to other necessary routing information detailed in Exhibit B, each payment shall clearly reference the Study Protocol
Number and PI name.

 

For
administrative convenience, various Study contact information may be attached hereto and incorporated by reference as Exhibit
C, entitled, “Administrative & Study Points of Contact.”

 

The
Institution’s tax identification number is: 59-0624458

 

    	 	2	 

     

    

 

3.
Confidentiality

 

3.1.
It is anticipated that in the performance of this Agreement, Sponsor and/or CRO on behalf of Sponsor may need to disclose to
Institution information which is considered confidential. The rights and obligations of the Parties with respect to such
information are as follows:

 

“Confidential
Information” refers to information of any kind which is disclosed to the Institution by Sponsor and/or CRO on behalf of
Sponsor for purposes of conducting the Study or Data (as defined below in Section 4) which:

 

		a)	by
                                         appropriate marking, is identified as confidential and proprietary at the time of disclosure;

 

		b)	if
                                         disclosed orally, is identified in a marked writing within thirty (30) days as being
                                         confidential.

 

Sponsor
and/or CRO on behalf of Sponsor will make reasonable efforts to mark Confidential Information as stated in (a) and (b) above.
However, to the extent such marking is not practicable, then in the absence of written markings, information disclosed (written
or verbal) that a reasonable person familiar with the Study would consider it to be confidential or proprietary from the context
or circumstances of disclosure shall be deemed as such.

 

Notwithstanding
the foregoing, Data and results generated in the course of conducting the Study are not Confidential Information for publishing
purposes in accordance with Section 9 of this Agreement. Institution agrees, for a period of five (5) years following the termination
or expiration of this Agreement, to use reasonable efforts, no less than the protection given their own confidential information,
to use Confidential Information received from Sponsor and/or CRO on behalf of Sponsor in accordance with this Section.

 

Institution
agrees to use Sponsor’s Confidential Information solely as allowed by this Agreement, and for the purposes of conducting
the Study. Institution agrees to make Sponsor’s Confidential Information available only to those of its, or its affiliated
hospitals’ employees, IRB members, personnel, agents, consultants, and vendors, and approved subcontractors, as applicable,
who require access to it in the performance of this Study, and are subject to similar terms of confidentiality.

 

3.2.
The obligation of non disclosure does not apply with respect to any of the Confidential Information that:

 

		a)	is
                                         or becomes public knowledge through no breach of this Agreement by Institution;
	 	 	 

		b)	is
                                         disclosed to Institution by a third party entitled to disclose such information without
                                         known obligation of confidentiality;
	 	 	 

		c)	is
                                         already known or is independently developed by Institution without use of Sponsor’s
                                         Confidential Information as shown by Institution’s contemporaneous written records;
	 	 	 

		d)	is
                                         necessary to obtain IRB approval of Study or required to be included in the written information
                                         summary provided to Study subject(s) and/or informed consent form;
	 	 	 

		e)	is
                                         released with the prior written consent of the Sponsor; or
	 	 	 
	 	f)	is
required to support the medical care of a Study Subject.

 

3.3.
Institution may disclose Confidential Information to the extent that it is required to be produced pursuant to a requirement
of applicable law, IRB, government agency, an order of a court of competent jurisdiction, or a facially valid administrative,
Congressional, or other subpoena, provided that Institution, subject to the requirement, order, or subpoena, promptly
notifies Sponsor. To the extent allowed under applicable law, Sponsor may seek to limit the scope of such disclosure and/or
seek to obtain a protective order. Institution will disclose only the minimum amount of Confidential Information necessary to
comply with law or court order as advised by Institution’s legal counsel.

 

    	 	3	 

     

    

 

3.4.
No license or other right is created or granted hereby, except the specific right to conduct the Study as set forth by
Protocol and under terms of this Agreement, nor shall any license or other right with respect to the subject matter hereof be
created or granted except by the prior written agreement of the Parties duly signed by their authorized
representatives.

 

3.5.
Upon Sponsor’s and/or CRO’s written request, Institution agrees to return all Confidential Information supplied
to it by Sponsor and/or CRO on behalf of Sponsor at Sponsor’s expense pursuant to this Agreement except that
Institution may retain such Confidential Information in a secure location for purposes of identifying and satisfying its
obligations and exercising its rights under this Agreement.

 

3.6
Institution may disclose the existence of this Agreement and any additional information necessary to ensure compliance with
applicable Federal, State and Institutional policies, regulations, and laws.

 

4.
Data Use/Ownership

 

“Data”
shall mean all data and information generated by Institution as a result of conducting the Study in accordance with the IRB approved
Protocol. Data does not include original Study subject or patient medical records, research notebooks, source documents, or other
routine internal documents kept in the Institution’s ordinary course of business operations, which shall remain the sole
and exclusive property of the Institution or medical provider. Sponsor owns and has the right to use the Data in accordance with
the signed informed consent and authorization form, applicable laws, and the terms of this Agreement. Notwithstanding any licenses
or other rights granted to Sponsor herein, but in accordance with the confidentiality and publication sections herein, Institution
shall retain the right to use the Data and results for its publication, IRB, regulatory, legal, clinical, educational, and internal
research purposes.

 

5.
HIPAA/HIPAA Privacy

 

5.1.
Institution shall comply with applicable laws and regulations, as amended from time to time, including without limitation,
the Health Insurance Portability and Accountability Act of 1996 and its implementing regulations (HIPAA) with respect to the
collection, use, storage, and disclosure of Protected Health Information (PHI) as defined in HIPAA. CRO and Sponsor, through
its agreement with CRO, shall collect, use, store, access, and disclose PHI collected from Study subjects only as permitted
by the IRB approved informed consent form or HIPAA authorization form obtained from a Study subject. Sponsor will collect,
use, store, and disclose any Subject Material, defined in Section 15, it receives only in accordance with the informed
consent form and, in any event, will not collect, use, store, or disclose any PHI attached to or contained within the Subject
Material in any manner that would violate this Section of the Agreement.

 

Institution
acknowledges that, pursuant to Section 111 of the Medicare, Medicaid, and SCHIP Extension Act of 2007 (“MMSEA”), Sponsor
has an obligation to submit certain reports to the Centers for Medicare & Medicaid Services with respect to Medicare beneficiaries
who participate in the Study and experience a research injury for which diagnosis or treatment costs are incurred. Sponsor and
CRO recognize that each party is subject to laws and regulations protecting the confidentiality of research subject information.
Accordingly: (1) Institution agrees upon prior written request to provide to Sponsor, or CRO as designated by Sponsor, certain
identifiable patient information required by MMSEA for Study subjects who are Medicare beneficiaries and incur medical costs in
association with a research injury and whose costs are reimbursed by Sponsor pursuant to this Agreement; and (2) Institution further
agrees to otherwise cooperate with Sponsor (and CRO as designated by Sponsor) to the extent necessary for Sponsor to meet its
MMSEA reporting obligations.

 

    	 	4	 

     

    

 

5.2.
CRO’s ability to review the Study subjects’ Study-related information contained in the Study subject’s
medical record shall be subject to reasonable safeguards for the protection of Study subject confidentiality and the Study
subjects’ informed consent form or HIPAA authorization form .

 

5.3.
Neither CRO, nor Sponsor through its agreement with CRO, shall attempt to identify, or contact, any Study subject unless
permitted by the informed consent form.

 

6.
Record Retention

 

As
applicable by law, Institution shall retain and preserve a copy of the Study records for the longer of:

 

		a)	two
                                         (2) years after a marketing authorization for Study Drug, or Study Device has been approved
                                         for the indication for which it was investigated or Sponsor has discontinued research
                                         on the Study Drug or Study Device;

 

		b)	such
                                         longer period as required by federal regulatory requirements; or

 

		c)	c)
                                         as requested by Sponsor at Sponsor’s reasonable storage expense.

 

7.
Monitoring and Auditing

 

7.1.
Site visits by Sponsor, CRO and/or another authorized designee (e.g., Study monitor) will be scheduled in advance for times
mutually acceptable to the Parties during normal business hours. Sponsor’s, CRO’s and/or authorized
designee’s access is subject to reasonable safeguards to ensure confidentiality of medical records and
systems.

 

7.2.
Upon becoming aware of an audit or investigation by a regulatory agency with jurisdiction over the Study, Institution agrees
to provide Sponsor with prompt notice of the auditor investigation. If legally permissible or allowable by the regulatory
agency and permissible in accordance with the Institution’s policy, Sponsor may be available or request to be present
with approval from auditor during such audit, but Sponsor will not alter or interfere with any documentation or practice of
Institution. Institution shall be free to respond to any regulatory agency inquiries and will provide Sponsor with a copy of
any formal response or documentation to the regulatory agency regarding the Study.

 

8.
Inventions, Discoveries and Patents

 

8.1.
It is recognized and understood that certain existing inventions and technologies, and those arising outside of the research
conducted under this Agreement, are the separate property of Sponsor or Institution and are not affected by this Agreement,
and neither Sponsor nor Institution shall have any claims to or rights in such separate inventions and
technologies.

 

    	 	5	 

     

    

 

8.2.
Any new patentable inventions, developments, or discoveries made during and in the performance of the Study
(“Inventions”) shall be promptly disclosed to Sponsor. Title to Inventions that necessarily use or necessarily
incorporate Sponsor’s Study Drug and/or Study Device shall reside with Sponsor (“Sponsor Inventions”).
Institution shall assign all Sponsor Inventions to Sponsor in writing. Title to Inventions other than Sponsor Inventions
(“Other Inventions”) shall reside with Sponsor if Sponsor personnel are the sole inventors, with Institution if
Institution personnel are the sole inventors, and shall be held jointly if both Institution and Sponsor personnel are
inventors. Institution’s obligations under Sections 8.2 and 8.3 hereunder shall be performed by its appropriate office
with technology transfer responsibilities, if required by and in accordance with Institution’s policies.

 

8.3.
To the extent that Institution owns sole or joint title in any such Other Inventions, Sponsor is hereby granted, without
option fee other than consideration of the Study sponsored herein and the reimbursement to Institution for patent expenses
incurred prior to or during the option period, an option to acquire an exclusive, worldwide, royalty-bearing license to
Institution’s rights to any Other Invention, which option shall extend for no more than ninety (90) days after
Sponsor’s receipt of an Invention disclosure from Institution (“Option Period”). Sponsor and Institution
shall use their reasonable efforts to negotiate, for a period not to exceed ninety (90) days after Sponsor’s exercise
of such option, a license agreement satisfactory to both parties (“Negotiation Period”). In the event Sponsor
fails to exercise its option within the Option Period, or Sponsor and Institution fail to reach agreement on the terms of
such license within the Negotiation Period, Institution shall have no further obligation to Sponsor under this Agreement with
regard to the specific Other Invention.

 

8.4.
Institution shall retain a royalty-free, irrevocable license to use for its own internal noncommercial research, educational
and patient care purposes, all Sponsor Inventions or Other Inventions licensed or assigned to Sponsor hereunder.

 

8.5.
Nothing contained in this Agreement shall be deemed to grant either directly by implication, estoppel, or otherwise any
license under any patents, patent applications, or other proprietary interest to any other inventions, discovery or
improvement of either Sponsor or Institution.

 

8.6.
CRO and Institution agree that the provisions of this Agreement are intended to be interpreted and implemented so as to
comply with all applicable federal laws, rules, and regulations, including without limitation the requirements of Rev. Proc.
2007-47; provided, however, if it is determined by the Internal Revenue Service or any other federal agency or
instrumentality (the “Government”) that the provisions of this Agreement are not in such compliance, then those
parties agree to modify the provisions and the implementation of this Agreement so as to be in compliance with all applicable
federal laws, rules, and regulations as determined by the Government.

 

9.
Publication

 

9.1.
Institution shall be free to publish, present, or use any Data and results arising out of its performance of the Protocol
(individually, a “Publication”). At least thirty (30) days prior to submission for Publication, Institution shall
submit to Sponsor for review and comment any proposed oral or written Publication (“Review Period”). Institution
will consider any such comments in good faith but is under no obligation to incorporate Sponsor’s suggestions. The
Review Period for abstracts or poster presentations shall be thirty (30) days. If during the Review Period, Sponsor notifies
Institution in writing that: (i) it desires patent applications to be filed on any inventions disclosed or contained in the
disclosures, Institution will defer Publication for a period not to exceed sixty (60) days, to permit Sponsor to file any
desired patent applications; and (ii) if the Publication contains Sponsor’s Confidential Information as defined in
Section 3 and Sponsor requests Institution in writing to delete such Sponsor’s Confidential Information, the
Institution agrees to delete such Sponsor’s Confidential Information only to the extent such deletion does not preclude
the complete and accurate presentation and interpretation of the Study results.

 

    	 	6	 

     

    

 

9.2.
The Parties agree that this Study is a multi-center clinical trial. Therefore, Institution agrees that the first Publication
of the results of the Study shall be made in conjunction with the presentation of a joint multi-center Publication of the
Study results with the Principal Investigators from all sites contributing Data, analyses, and comments. However, Institution
may publish the Data and Study results individually in accordance with this Section 9 upon first occurrence of one of the
following: (i) multi center Publication is published; (ii) no multi-center publication is submitted within eighteen (18)
months after conclusion, abandonment, or termination of the Study at all sites; or (iii) Sponsor confirms in writing there
will be no multi-center Publication.

 

9.3.
If no multi-center Publication occurs within eighteen (18) months of the completion of the Study at all sites, upon request
by Institution, Sponsor will provide such Institution access to the aggregate Data from all Study sites.

 

9.4.
If the Institution, through its Principal Investigator, is identified to participate in the multi center Publication: (i)
Institution will have the opportunity to review the aggregate multi-center Data, upon request; and (ii) consistent with the
International Committee of Medical Journal Editors (ICMJE) regulations, Institution will have adequate opportunity to review
and provide input on any abstract or manuscript prior to its submission for Publication. Institution also retains the right,
on behalf of its Principal Investigator, to decline to be an author on any Publication.

 

10.
Use of Name

 

10.1.
Neither Institution nor CRO may use the name, trademark, logo, symbol, or other image or trade name of the other Party or
their employees and agents in any advertisement, promotion, or other form of publicity or news release or that in any way
implies endorsement without the prior written consent of an authorized representative of the other Party whose name is being
used. Such approval will not be unreasonably withheld.

 

10.2.
Institution and Sponsor understand that the amount of any payment made hereunder may be disclosed and made public by the
other party as required by law or regulation, including the Patient Protection and Affordable Care Act of 2010, provided that
the disclosure clearly designates the payment as having been made to Institution for research and not to the
physician.

 

10.3.
Institution may acknowledge the Sponsor’s support, including but not limited to financial support as may be required by
academic journals, professional societies, funding agencies, and applicable regulations. Notwithstanding anything to the
contrary in this Agreement, Institution may publicly post information about the Study on Institution’s clinical trials
directory/website. Additionally, notwithstanding anything herein to the contrary, Institution shall have the right to post
Sponsor’s and/or CRO’s names, the Study title, and the Study period, and funding amount, on Institution publicly
accessible lists of research conducted by the Institution.

 

11.
Indemnification and Limitation of Liability

 

11.1
Sponsor’s indemnification obligations are outlined in a separate Letter of Indemnification, attached hereto as Exhibit
D.

 

    	 	7	 

     

    

 

 11.2. CRO expressly disclaims any liability in connection with the Study Drug or Study Device, including any liability for any claim arising out of a condition caused by or allegedly caused by any Study procedures associated with such product except to the extent that such liability is caused by the negligence, willful misconduct or breach of this Agreement by CRO.

 

11.3.
Institution shall have no obligation to indemnify CRO and CRO shall have no obligation to indemnify Institution.

 

12.
Subject Injury

 

Sponsor’s
subject injury obligations are outlined in Exhibit D.

 

13.
Insurance

 

13.1.
Institution shall, at its sole cost and expense maintain a policy or program of insurance or self- insurance at the level of
at least $1,000,000 per occurrence (or per claim) and $3,000,000 annual aggregate to support its obligations assumed in this
Agreement. However, if Institution is a public entity entitled to governmental immunity protections under applicable state
law, then Institution may provide liability coverage in accordance with any limitations associated with the applicable
law.

 

13.2.
CRO shall maintain an insurance policy or a program of self-insurance at levels sufficient to support its obligations assumed
herein.

 

13.3.
Upon written request, either Party will provide evidence of its insurance or self-insurance acceptable to the other Party. A
Party’s inability to meet its insurance obligation constitutes material breach of this Agreement.

 

14.
Term and Termination

 

14.1.
This term of this Agreement shall commence upon the Effective Date and terminate upon the completion of the Parties’
Study-related activities under the Agreement, unless terminated early as further described in this Section.

 

14.2.
CRO has the right to terminate this Agreement upon thirty (30) days prior written notice to the Institution. This Agreement
may be terminated immediately at any time for any reason by the Institution or CRO when, in their judgment or that of the
Principal Investigator, the Institution’s IRB, Scientific Review Committee, if applicable, or the Food and Drug
Administration, it is determined to be inappropriate, impractical, or inadvisable to continue, in order to protect the Study
subjects’ rights, welfare, and safety, or the IRB otherwise disapproves the Study. If for any reason Principal
Investigator becomes unavailable to direct the performance of the work under this Agreement, Institution shall promptly
notify CRO. If the Parties are unable to identify a mutually acceptable successor, this Agreement may be terminated by either
Party upon thirty (30) days written notice.

 

 14.3. Notwithstanding the above a Party may, in addition to any other available remedies:

 

		a)	immediately
                                         terminate this Agreement upon the other Party’s material failure to adhere to the
                                         Protocol, except for deviation required to protect the rights, safety, and welfare of
                                         Study subjects; and/or

 

		b)	terminate
                                         this Agreement upon the other Party’s material default or breach of this Agreement,
                                         provided that the defaulting/breaching Party fails to remedy such material default, breach,
                                         or failure to adhere to the Protocol within thirty (30) business days after written notice
                                         thereof.

 

    	 	8	 

     

    

 

14.4.
In addition to the above, this Agreement may be terminated by Institution in the event of a material default or breach of
this Agreement by CRO, or by CRO in the event of a material breach of this Agreement by Institution, provided that the
defaulting/breaching party fails to remedy such material default or breach within thirty (30) business days after written
notice thereof.

 

14.5.
In the event that this Agreement is terminated prior to completion of the Study, for any reason, Institution
shall:

 

		a)	notify
                                         the IRB that the Study has been terminated;

 

		b)	cease
                                         enrolling subjects in the Study;

 

		c)	cease
                                         treating Study subjects under the Protocol as directed by CRO to the extent medically
                                         permissible and appropriate;

 

		d)	terminate,
                                         as soon as practicable, all other Study activities; and

 

		e)	furnish
                                         to CRO any required final report for the Study in the form reasonably acceptable to CRO.

 

Promptly
following any such termination, Institution will provide to CRO copies of Data collected pursuant to the Study Protocol. Upon
Sponsor’s or CRO’s written request, Institution shall provide to the requesting party, at Sponsor’s or CRO’s
expense, all Sponsor’s Confidential Information provided under this Agreement provided, however, that Institution may retain
such copy of Confidential Information for record keeping purposes, monitoring its obligations, and exercising its rights hereunder,
subject to Institution’s ongoing compliance with the confidentiality and non-use obligations set forth in this Agreement.

 

14.6.
If this Study is terminated early by either Party, the Institution shall be reimbursed for all work completed, on a pro rata
basis, and reasonable costs of bringing the Study to termination incurred through the date of termination, and for
non-cancelable commitments properly incurred through that date. Upon receipt of notice of termination, Institution will use
reasonable efforts to reduce or eliminate further costs and expenses and will cooperate with CRO to provide for an orderly
wind-down of the Study.

 

14.7.
Subsections 1.4, 1.6, and 14.6, and Sections 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 (and the attached Letter of Indemnification), 12,
13, 15, 19 and 23, shall survive any termination or expiration of this Agreement, except that Section 3 shall survive for the
period stated in Section 3.1. Any provision of this Agreement that by its nature and intent remains valid after termination
will survive termination.

 

15.
Subject Material

 

15.1.
Subject Material means any biologic material of human origin including, without limitation, tissues, blood, plasma, urine,
spinal fluid, or other fluids derived from the Study subjects in accordance with and pursuant to the Protocol (“Subject
Material”).

 

    	 	9	 

     

    

 

 15.2. Institution agrees to make the Subject Material available to the Sponsor in accordance with the Protocol for the purposes of the Study. The Subject Material may be used by the Sponsor, central lab, or other contracted party only as allowed by the Study subject’s informed consent form or pertinent institutional review board(s). Sponsor’s use of Subject Materials, other than as allowed by the Study subject’s informed consent form, will require additional IRB review and approval.

 

 16. Subcontract

 

If
applicable, Institution has the right to subcontract to other sites to conduct the Study in accordance with the Protocol with
terms consistent with this Agreement with written approval of the Sponsor, which approval shall not be unreasonably withheld.
If Institution subcontracts any Study related duties, Institution shall contract with such subcontractors incorporating terms
substantially similar to the terms herein. Such subcontracts may be provided to the CRO upon written request.

 

The
Parties acknowledge and agree that the Sponsor and each of its affiliates is a third-party beneficiary to this Agreement.

 

 17. Notices

 

Any
notice, authorization, approval, consent or other communication will be in writing and deemed given:

 

		a)	Upon
                                         delivery in person;

		b)	Upon
                                         delivery by courier;

		c)	Upon
                                         delivery date by a nationally-recognized overnight delivery service such as FedEx.

 

If
to CRO:

Cancer
Insight, LLC

Attn: Steven White

Chief Operating Officer

1422
E Grayson, 3rd Floor

San Antonio, TX 78208

210-884-0810

swhite@cancerinsight.com

 

If
to Sponsor:

BriaCell
Therapeutics Corp.

820
Heinz Avenue

Berkeley,
CA 94710

Tel:
1-888-485-6340

Fax:
424-245-3719

 

lf
to Institution:

University
of Miami

1320
S. Dixie Highway, Suite 650

Coral Gables, FL 33146

Tel:
305-284-3952

CRIS@med .miami.edu

 

    	 	10	 

     

    

 

With
a copy to Principal Investigator:

Carmen
Calfa, M.D.

8100 SW 10 Street,

Crossroads
Office Park Building 3

Plantation, FL 33324

Telephone:
(305)243-3379

Email: cic25@miami.edu

 

18.
Independent Contractor

 

It
is mutually understood and agreed that the relationship between Institution and CRO is that of independent contractors. No party
shall represent itself as the agent, employee, partner, joint venturer, or servant of the other. Except as specifically set forth
herein, no party shall have nor exercise any control or direction over the methods by which the other party performs work or obligations
under this Agreement. Further, nothing in this Agreement is intended to create any partnership, joint ventures, lease, or equity
relationship, expressly or by implication, among those parties.

 

19.
Clinical Trial Registry

 

Prior
to enrollment of the first subject in the Study, Sponsor will register the Study on www.clinicaltrials.gov in accordance with
the requirements of the International Committee of Medical Journal Editors (ICMJE) and Public Law 110-85. Results of this Study
will be reported in compliance with applicable laws.

 

20.
Non-Referral/Anti-Corruption Language

 

20.1.
Institution and CRO, on behalf of Sponsor, agree that it is not their intent under this Agreement to induce or encourage the
unlawful referral of subjects or business between the Parties, and there shall not be any requirement under this Agreement
that those parties, their employees or affiliates, including their medical staff, engage in any unlawful referral of subjects
to, or order or purchase products or services from, one of those parties.

 

20.2.
Institution and CRO, on behalf of Sponsor, agree that their employees, who are involved in the conduct of the Study, will not
offer, pay, request or accept any bribe, inducement, kickback or facilitation payment, and shall not make or cause another to
make any offer or payment to any individual or entity for the purpose of influencing a decision for the benefit of one of
those parties.

 

21.
Force Majeure

 

If
either Party hereto shall be delayed or hindered in, or prevented from, the performance of any act required hereunder for any
reason beyond such Party’s direct control, including but not limited to, strike, lockouts, labor troubles, governmental
or judicial actions or orders, riots, insurrections, war, acts of God, inclement weather, or other reason beyond the Party’s
control (a “Disability”) then such Party’s performance shall be excused for the period of the Disability. Any
Study timelines affected by a Disability shall be extended for a period equal to the delay and any affected Budget shall be adjusted
to account for cost increases or decreases resulting from the Disability. The Party affected by the Disability shall notify the
other Party of such Disability as provided for herein.

 

    	 	11	 

     

    

 

22.
Counterparts

 

This
Agreement may be executed in any number of counterparts, each of which shall be an original and all of which together shall constitute
one and the same document, and is binding on all Parties notwithstanding that each of the Parties may have signed different counterparts.
Facsimiles or scanned copies of signatures or electronic images of signatures shall be considered original signature unless prohibited
by applicable law.

 

23.
Debarment

 

The
Institution certifies that to its knowledge neither it, nor any of its employees, agents or other persons performing the
Study under its direction, is currently debarred, suspended, or excluded under the Federal Food, Drug and Cosmetic Act, as
amended, or disqualified under the provisions of 21 CFR §312.70. In the event that the Principal Investigator or
any Study personnel becomes debarred or disqualified during the term of this Agreement or within 1 year after termination of
the Study, the Institution agrees to promptly notify CRO after learning of such event. Institution certifies that it is not
excluded from a federal health care program, including Medicare and Medicaid. In the event an Institution becomes excluded
during the term of this Agreement or within 1 year after termination of the Study, the Institution agrees to promptly notify
CRO after learning of such event.

 

 24. Choice of Law -Intentionally omitted

 

25.
Entire Agreement

 

Section
and clause headings are used herein solely for convenience of reference and are not intended as substantive parts of the Parties’
agreement. This ACTA incorporates the Exhibits referenced herein. This written ACTA constitutes the entire agreement between the
Parties concerning the subject matter, and supersedes all other or prior agreements or understandings, whether written or oral,
with respect to that subject matter. Any changes made to the terms, conditions or amounts cited in this ACTA require the written
approval of each Party’s authorized representative.

 

The
authorized representatives of the Parties have signed this ACTA as set forth below.

 

	University of Miami 	 	Cancer Insight, LLC
	 	 	 	 	 
	By:		 	By:	
	 	 	 	 	 
	Name:	Jill
    Tincher	 	Name:
    	Steven
    White
	 	 	 	 	 
	Title:
    	Executive
    Director, Research Administration	 	Title:	Chief
    Operating Officer
	 	 	 	 	 
	Date:	9/4/18	 	Date:	August
    31, 2018

 

    	 	12	 

     

    

 

READ
AND ACKNOWLEDGED

 

	By:		 
	 	 	 
	Name:	Carmen
    Calfa, M.D.	 
	 	 	 
	Title:	Principal
    Investigator	 
	 	 	 
	Date
    :	8/31/18	 

 

    	 	13	 

     

    

 

EXHIBIT
A

PROTOCOL

 

See
attached and incorporated Protocol and consent form.

 

    	 	14	 

     

    

 

EXHIBIT
B

BUDGET

 

Fee
and Payment Schedule:

 

		A.	This
                                         Budget has been negotiated at fair and reasonable value. Institution has not been influenced
                                         to participate in this Study based on financial or other inducements from Sponsor. The
                                         compensation may be used at the discretion of Institution to offset the costs of the
                                         Study. For Study subject visit and Study conduct reimbursements, an item listed herein
                                         will be considered payable upon Institution’s complete and accurate data entry
                                         into the applicable electronic data capture system (EDC) of all assessments associated
                                         with that visit in the EDC.

 

		B.	Sponsor
                                         will not be liable for any payment in excess of the fees and costs provided herein except
                                         upon Sponsor’s prior written agreement. Institution may submit to Sponsor a revised
                                         budget requesting additional funds at such time as expenses may reasonably be projected
                                         to exceed the fees and costs provided herein.

 

		C.	The
                                         compensation per Study subject will be earned by Institution and made payable by Cancer
                                         Insight as follows:

 

		i.	 	$3,816.00
                                         will be paid upon completion of Cycle One, as defined by the Protocol;

 

		ii.	 	$3,816.00
                                         will be paid upon completion of Cycle Two, as defined by the Protocol;

 

		iii.	 	$3,816.00
                                         will be paid upon completion of Cycle Three, as defined by the Protocol;

 

		iv.	 	$3,816.00
                                         will be paid upon completion of Cycle Four, as defined by the Protocol;

 

		v.	 	$3,816.00
                                         will be paid upon completion of Cycle Five, as defined by the Protocol;

 

		vi.	 	$3,816.00
                                         will be paid upon completion of Cycle Six, as defined by the Protocol;

 

		vii.	 	$3,816.00
                                         will be paid upon completion of Cycle Seven, as defined by the Protocol;

 

		viii.	 	$3,816.00
                                         will be paid upon completion of Cycle Eight, as defined by the Protocol;

 

		ix.		$3,816.00
                                         will be paid upon completion of Cycle Nine, as defined by the Protocol;

 

		x.	 	$3,816.00
                                         will be paid upon completion of Cycle Ten, as defined by the Protocol;

 

		xi.	 	$3,816.00
                                         will be paid upon completion of Cycle Eleven, as defined by the Protocol;

 

		xii.	 	$3,816.00
                                         will be paid upon completion of Cycle Twelve, as defined by the Protocol;

 

		xiii.	 	$3,816.00
                                         will be paid upon completion of Cycle Thirteen, as defined by the Protocol;

 

		xiv.	 	$3,816.00
                                         will be paid upon completion of Cycle Fourteen, as defined by the Protocol

 

		xv.	 	$3,816.00
                                         will be paid upon completion of Cycle Fifteen, as defined by the Protocol

 

		xvi.	 	$3,816.00
                                         will be paid upon completion of Cycle Sixteen, as defined by the Protocol

 

		xvii.	 	$3,816.00
                                         will be paid upon completion of Cycle Seventeen, as defined by the Protocol.

 

    	 	15	 

     

    

 

		D.	Where
                                         Institution utilizes Western IRB (“WIRB”) as their central IRB, Cancer Insight
                                         will pay for WIRB costs directly and Institution may direct WIRB to invoice Cancer Insight
                                         directly. This study was reviewed by local IRB. Fee schedule in link for reference: http://hsro.med.miami.edu/fees.

 

		E.	Start-up
                                         funding will be provided in the amount of $12,390.00 and payable upon execution of the
                                         Agreement, which may be used at the discretion of Institution to offset the costs of
                                         the Study.

 

		F.	The
                                         following administrative and other fees shall be invoice able to Sponsor:

 

		i.	 	CRIS
                                         Fee (one-time) of $2,500.00;

 

		ii.	 	Research
                                         Compliance Fee (one-time) of $350.00;

 

		iii.	 	CTRS
                                         Fee (one-time) of $1,290.00;

 

		iv.	 	Site
                                         Initiation Visit (one-time) of $1,500.00;

 

		v.	 	Pharmacy
                                         Startup Fee (one-time) of $2,580.00;

 

		vi.	 	Pharmacy
                                         Maintenance (annual) of $900.00;

 

		vii.	 	Pharmacy
                                         Closeout (one-time) of $650.00;

 

		viii.	 	SAE
                                         Reports (per occurrence) of $660.00;

 

		ix.	 	IND
                   reports (annually) $2,330.00;

 

		x.	 	Records
                                         Retention (one-time) of $2,230.00;

 

		xi.	 	Subsequent
                                         IRB submissions (per occurrence) of $790.00;

 

		xii.	 	Reconsenting
                                         Fee (per subject, per consent) of $190.00;

 

		xiii.	 	Monitor
                                         Visit (per day) of $900.00;

 

		xiv.	 	Site
                                         Closeout Visit (one-time) of $1,440.00;

 

		xv.	 	Not-for-cause
                                         FDA audits (per day) of $1,140.00;

 

		xvi.	 	ICF
                                         translation (per word) pf $0.41;

 

		G.	As
                                         required by Study procedures and under the terms of the Study Protocol, Study subjects,
                                         at different time points, may require the following tests, scans, and/or procedures.
                                         When such tests and labs are not deemed routine by Investigator for a Study subject at
                                         the given time point and are performed to satisfy the Study Protocol’s requirements
                                         for data collection, Sponsor will reimburse Institution at the rates listed below, which
                                         are inclusive of any institutional overhead.

 

    	 	16	 

     

    

 

	 	CT
    scan of chest: $882.37	CBC:
    $25.74
	 	CT
    scan of abdomen & pelvis: $965.66	CMP:
    $34.98
	 	Chest
    x-ray: $381.47	GGT:
    $23.85
	 	Bone
    scan: $1,095.52	LOH:
    $20.00
	 	MRI
    chest: $2,141.32	Uric
    acid: $14.98
	 	MRI
    abdomen: $1,518.61	PT:
    $13.02
	 	MRI
    pelvis: $1,517.62	aPTT:
    $19.90
	 	Breast
    mammogram: $429.87	Serum
    pregnancy test: $49.88
	 	ECG:
    $174.86	Urinalysis:
    $7.16
	 	Echo:
    $2,030.78	Serological
    marker cTn: $33.46
	 	MUGA:
    $1,111.46	Serological
    marker NT-proBNP: $112.42
	 	PET:
    $3,890.27	 

 

		H.	Invoices
                                         shall be sent to Cancer Insight via email to Tiffany Nunn at tnunn@cancerinsight.com
                                         with cc copy to Steven White at swhite@cancerinsight.com.

 

		I.	Payments
                                         shall be sent no later than thirty (30) days from receipt and approval of invoices. Payments
                                         will be issued via electronic funds transfer whenever possible and under the following
                                         instructions. In the event that such method of payment is rendered impossible or impractical,
                                         payments will be issued via check and mailed to the address included on the associated
                                         invoice.

 

Bank
Name: Bank of America, N.A.

Account
Number: 1595794746

Routing
Number: 063100277

 

    	 	17	 

     

    

 

EXHIBIT
C

ADMINISTRATIVE
AND STUDY POINTS OF CONTACT

 

CRO
Clinical Department Point of Contact:

 

Karen
Arrington

karrington@cancerinsight.com

 

CRO
Regulatory Department Point of Contact:

 

Susie
Hargrove 

shargrove@cancerinsight.com

 

CRO
Administrative and Billing Department Point of Contact:

 

Steven
White 

swhite@cancerinsight.com

 

    	 	18	 

     

    

 

EXHIBIT
D

LETTER
OF INDEMNIFICATION (LOI)/SUBJECT INJURY

 

INSTITUTION:
UNIVERSITY OF MIAMI (the “Institution”)

 

	TITLE OF
    CLINICAL TRIAL: 	“A Phase I/Ila Rollover Study of the Whole-Cell Vaccine BriaVaxTM in Metastatic
    or Locally Recurrent Breast Cancer Patients in Combination with Ipilimumab or Pembrolizumab”

 

CRO:
Cancer Insight, LLC

 

STUDY
NUMBER: BRI-ROL-001

 

	1)	Institution
                                         has entered into an Accelerated Clinical Trial Agreement (ACTA) with CRO to participate
                                         in the above sponsored Study. CRO has been engaged by BriaCell Therapeutics Corp. (the
                                         “Sponsor”) to arrange and administer this BriaCell Therapeutics Corp. sponsored
                                         multi-center clinical trial.

 

	2)	Sponsor
                                         has delegated to CRO responsibility for the management and monitoring of this Study.
                                         Sponsor has further authorized CRO to bind Sponsor to its obligations within the Accelerated
                                         Clinical Trial Agreement for this Study executed between CRO and Institution. Sponsor
                                         accepts responsibility for its obligations contained in that Accelerated Clinical Trial
                                         Agreement.

 

	3)	Institution
                                         agrees to participate by allowing the Study to be undertaken utilizing such facilities,
                                         personnel and equipment as Institution may reasonably need for its conduct of the Study.

 

	4)	In
                                         consideration of such participation by Institution, and subject to paragraph 5 below,
                                         the Sponsor shall defend, indemnify, and hold harmless the Institution and its medical
                                         affiliates and affiliated hospitals, and each of their trustees, officers, directors,
                                         governing bodies, subsidiaries, affiliates, investigators, employees, IRB members, agents,
                                         successors, heirs and assigns (collectively referred to as “Institution’s
                                         Indemnitees”), from and against any third party claims, loss, damage, cost and
                                         expense of claims (including reasonable attorney’s fees) and suits (“Claims”),
                                         alleged to be caused by or arising from the conduct of the Study or use of the Study
                                         Drug or Study Device under this Agreement or from the use of the Study results, regardless
                                         of the legal theory asserted.

 

	5)	Sponsor
                                         shall have no obligation to provide such indemnification to the extent that such Claim
                                         is solely caused by Institution’s Indemnitee(s)’: (1) failure to adhere to
                                         and comply with all material and substantive specifications and directions set forth
                                         in the Protocol (except to the extent such deviation is reasonable to protect the rights,
                                         safety and welfare of the Study subjects); (2) failure to comply with all applicable
                                         laws and regulations in the performance of the Study; or (3) if such claim is directly
                                         caused by the negligent acts or omissions of Institution’s Indemnitees(s).

 

	6)	Subject
                                         to the limits and without waiving any immunities provided under applicable law (including
                                         constitutional provisions, statutes and case law) regarding the status, powers and authority
                                         of the Institution or the Institution’s principal(s), Institution shall indemnify,
                                         hold harmless and defend Sponsor, its directors, officers, employees and agents, (“Sponsor’s
                                         Indemnitees”) from and against only those third-party Claims to the extent directly
                                         attributable to Institution’s negligence in its conduct of the Study. Notwithstanding
                                         the above, Institution shall have no obligation to indemnify Sponsor for any other Claims
                                         (including, but not limited to, infringement or product liability Claims).

 

    	 	19	 

     

    

 

	7)	The
                                         indemnified party shall give notice to the indemnifying party promptly upon receipt of
                                         written notice of a Claim for which indemnification may be sought under this Agreement,
                                         provided, however, that failure to provide such notice shall not relieve indemnifying
                                         party of its indemnification obligations except to the extent that the indemnifying party’s
                                         ability to defend such Claim is materially, adversely affected by such failure. Indemnifying
                                         party shall not make any settlement admitting fault or incur any liability on the part
                                         of the indemnified party without indemnified Party’s prior written consent, such
                                         consent not to be unreasonably withheld or delayed. The indemnified Party shall cooperate
                                         with indemnifying Party in all reasonable respects regarding the defense of any such
                                         Claim, at indemnifying Party’s expense. The indemnified Party shall be entitled
                                         to retain counsel of its choice at its own expense. In the event a Claim falls under
                                         this indemnification clause, in no event shall the indemnified Party compromise, settle
                                         or otherwise admit any liability with respect to any Claim without the prior written
                                         consent of the indemnifying Party, and such consent not to be unreasonably withheld or
                                         delayed.

 

	8)	EXCEPT
                                         FOR THE PARTIES’ OBLIGATIONS TO INDEMNIFY EACH OTHER AS STATED ABOVE, NEITHER PARTY
                                         SHALL BE LIABLE TO THE OTHER PARTY FOR SPECIAL, CONSEQUENTIAL OR INCIDENTAL DAMAGES ARISING
                                         OUT OF OR IN CONNECTION WITH THIS AGREEMENT, EVEN IF ADVISED OF THE POSSIBILITY OF THE
                                         SAME.
	 	 

	9)	If
                                         a Study subject suffers an adverse reaction, illness, or injury which, in the reasonable
                                         judgment of Institution, was directly caused by a Study Drug or Study Device or any properly
                                         performed procedures required by the Protocol, Sponsor shall reimburse for the reasonable
                                         and necessary costs of diagnosis and treatment of any Study subject injury, including
                                         hospitalization, but only to the extent such expenses are not attributable to: (i) Institution’s
                                         negligence or willful misconduct; or (ii) the natural progression of an underlying or
                                         pre-existing condition or events, unless exacerbated by participating in the Study.

 

	10)	Sponsor
                                         shall, at its sole cost and expense, procure and maintain commercial general liability
                                         insurance, clinical trial insurance and products liability insurance or equivalent self-insurance,
                                         unless otherwise indicated in an attachment, in amounts not less than $5,000,000.00 per
                                         occurrence and $5,000,000.00 annual aggregate. Such commercial general liability insurance,
                                         clinical trial insurance and products liability insurance or equivalent self-insurance
                                         shall provide contractual liability coverage for Sponsor’s indemnification obligations
                                         herein.

 

	11)	Upon
                                         written request, Sponsor will provide evidence of its insurance policy or a program of
                                         self insurance and will provide Institution with written notice of any material change
                                         in its coverage which would affect Sponsor’s ability to meet its obligations under
                                         this Agreement. Sponsor’s inability to meet its insurance obligation constitutes
                                         material breach of this LOI and the Accelerated Clinical Trial Agreement executed with
                                         the CRO for this Study.

 

	12)	During
                                         the Study and for at least two (2) years following the completion of the Study at all
                                         sites, Sponsor shall promptly provide Institution and Principal Investigator with the
                                         written report of any findings, including Study results and any routine monitoring findings
                                         in site monitoring reports, and data safety monitoring committee reports including, but
                                         not limited to, data and safety analyses, and any Study information that may (i) affect
                                         the safety and welfare of current or former Study subjects, or (ii) influence the conduct
                                         of the Study. Institution and/or Principal Investigator will communicate findings to
                                         the IRB and Study subjects, as appropriate.

 

    	 	20	 

     

    

 

	13	Except
                                         as permitted in Article 10.3 in the ACT A, neither institution nor Sponsor may use the
                                         name, trademark, logo, symbol, or other image or trade name of any other party or their
                                         employees and agents in any advertisement, promotion, or other form of publicity or news
                                         release or that in any way implies endorsement without the prior written consent of an
                                         authorized representative of the other party whose name is being used. Such approval will
                                          not be unreasonably withheld.

 

The
authorized representatives have signed this Letter of lndemnification as set forth below.

 

	University of Miami 	 	BriaCell Therapeutics Corp.
	 	 	 	 	 
	By:		 	By:	
	 	 	 	 	 
	Name:	Jill
    F. Tincher, MBA, CRA 	 	Name:
    	William
    V. Williams
	 	 	 	 	 
	Title:
    	Executive
    Director, ORA	 	Title:	President
    and CEO
	 	 	 	 	 
	Date:	9/4/18	 	Date:	2018
    August 31

 

READ
AND ACKNOWLEDGED

 

	By:		 
	 	 	 
	Name:	Carmen
    Calfa, M.D.	 
	 	 	 
	Title:	Principal
    Investigator	 
	 	 	 
	Date
    :	8/31/18	 

 

    	 	21

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