Document:

REGISTRATION RIGHTS AGREEMENT

      This  REGISTRATION  RIGHTS  AGREEMENT (the  "Agreement")  is dated as of
March 30, 2000 between  Senesco  Technologies,  Inc.,  a Delaware  corporation
(the "Company"), and Fahnestock & Co. Inc. (the "Purchaser").

                                    RECITALS
                                    --------

      WHEREAS,  Fahnestock  is the  holder of a five year  warrant  to  purchase
100,000 shares of the Company's common stock (the "Warrant"),  dated as of March
30, 2000; and

      WHEREAS,  pursuant  to  the  financial  advisory  and  investment  banking
agreement  made by and between the  Purchaser  and the Company,  dated as of the
date hereof (the "Financial  Advisory and Investment  Banking  Agreement"),  the
Company is obligated to grant registration  rights for shares of common stock of
the Company,  $0.01 par value (the "Common  Stock"),  issued by the Company upon
the exercise of the Warrant, in connection with resales by the Purchaser of such
Common Stock; and

      WHEREAS,  the Company will enter into similar Registration Rights with the
purchasers of Common Stock pursuant to that certain  Placement Agent  Agreement,
dated as of March 30, 2000,  by and between the Company and the  Purchaser,  and
whose  rights  shall vest on a pari passu basis with the  Purchaser  herein (the
"Private Placement");

      WHEREAS,  the  Company  and the  Purchaser  now  desire to enter into this
Agreement in order to facilitate such resales.

                                    AGREEMENT
                                    ---------

      The parties hereto agree as follows:

                                    ARTICLE 1
                                   DEFINITIONS

      1.1   DEFINITIONS.  The  following  terms,  as  used  herein,  have  the
following meanings.

      "Board" means the Board of Directors of the Company.

      "Business  Day"  means any day except a  Saturday,  Sunday or other day on
which banks in New Jersey are authorized by law to close.

      "Common Stock" means the Common Stock of the Company,  $0.01 par value per
share.

      "Closing  Date"  shall  mean the  Closing  Date as  defined  in the  Stock
Purchase  Agreements  entered  into  by the  Company  and  other  purchasers  in
connection with the Private Placement.

      "Commission" means the Securities and Exchange Commission.

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      "Company" means Senesco Technologies, Inc., a Delaware corporation.

      "Company Registration  Statement" means the Registration  Statement of the
Company  relating to the  registration  for sale of Common Stock,  including the
Prospectus  included therein,  all amendments and supplements thereto (including
post-effective  amendments)  and  all  exhibits  and  material  incorporated  by
reference therein, but excluding the current registration  statement on Form S-3
to be filed with the Commission in connection with the registration of shares of
Common  Stock  issued and sold by the Company as part of the  private  placement
consummated  in May 1999 and  certain  other  shares  of  Common  Stock  sold by
affiliates of the Company.

      "Effective  Time"  means  the date of  effectiveness  of any  Registration
Statement.

      "Exchange Act" means the Securities Exchange Act of 1934, as amended.

      "Financial  Advisory and  Investment  Banking  Agreement"  has the meaning
given to it in the recitals to this Agreement.

      "Holders" has the meaning given to it in Section 2.1(b) hereof.

      "NASD" means the National Association of Securities Dealers, Inc.

      "Person" means an individual, corporation, partnership, association, trust
or other entity or organization, including a government or political subdivision
or an agency or instrumentality thereof.

      "Private  Placement"  has the meaning  given to it in the recitals to this
Agreement.

      "Prospectus" means the prospectus included in any Registration  Statement,
as  amended  or  supplemented  by any  prospectus  supplement  and by all  other
amendments  thereto,  including  post-effective  amendments,  and  all  material
incorporated by reference into such Prospectus.

      "Purchaser" means Fahnestock & Co. Inc.

      "Registration  Statements" means the Company Registration  Statement and
the Shelf Registration Statement.

      "Restricted  Securities"  means any  Securities  until (i) a  registration
statement covering such Securities has been declared effective by the Commission
and  such   Securities   have  been  disposed  of  pursuant  to  such  effective
registration   statement,   (ii)  such  Securities  qualify  to  be  sold  under
circumstances  in Rule 144(k) (or any similar  provisions then in force),  (iii)
such  Securities  are  otherwise  transferred,  the Company has  delivered a new
certificate  or other  evidence of ownership for such  Securities  not bearing a
legend  restricting  further  transfer and such Securities may be resold without
registration under the Securities Act, or (iv) such Securities shall have ceased
to be outstanding.

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<PAGE>

      "Securities"  means the shares of Common Stock held by the Purchaser  that
were  acquired  through the  exercise of the Warrant by the  Purchaser,  and any
securities  issues  in  respect  of such  shares  upon any  stock  split,  stock
dividend,  recapitalization,  merger,  consolidation,  reorganization or similar
event.

      "Securities Act" means the Securities Act of 1933, as amended.

      "Shelf  Registration  Statement" means the  registration  statement of the
Company relating to the shelf  registration for resale of Restricted  Securities
contemplated by Section 2.2 herein,  including the Prospectus  included therein,
all amendments and supplements thereto (including post-effective amendments) and
all exhibits and material incorporated by reference therein.

      "Warrant" has the meaning given to it in the recitals to this Agreement.

      As used in this Agreement,  words in the singular include the plural,  and
in the plural include the singular.

                                    ARTICLE 2
                               REGISTRATION RIGHTS

      2.1   SECURITIES SUBJECT TO THIS AGREEMENT.

      (a) The  Securities  entitled to the  benefits of this  Agreement  are the
Restricted  Securities,   but  only  for  so  long  as  they  remain  Restricted
Securities.

      (b) A Person is deemed to be a holder of Restricted  Securities  (each,  a
"Holder")  whenever  such  Person is the  registered  holder of such  Restricted
Securities on the Company's books and records.

      2.2   SHELF REGISTRATION.

      (a)   The Company shall:

            (i)  cause to be  filed  with the  Commission  a Shelf  Registration
Statement on Form S-3 (or, if such form is superseded by a successor  form, such
successor  form);  or  if  Form  S-3  is  not  available  with  respect  to  the
registration  of the  Restricted  Securities,  any form  which  the  Company  is
permitted to use under the Securities  Act, which Shelf  Registration  Statement
shall  provide for resales of all  Restricted  Securities,  the Holders of which
shall have provided to the Company the information  required pursuant to Section
2.2(c) herein; and

            (ii)  use  its  best   reasonable   efforts   to  cause  such  Shelf
Registration  Statement to be declared  effective by the Commission  within nine
(9) months from the last Closing Date.

      (b) In connection with the Shelf Registration Statement, the Company shall
comply with all the provisions of Section 2.4 below and shall use its reasonable
efforts  to  effect  such

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<PAGE>

registration  to permit  the sale of the  Restricted  Securities  being  sold in
accordance  with the  intended  method or methods of  distribution  thereof  (as
indicated  in the  information  furnished  to the  Company  pursuant  to Section
2.2.(c)).  Subject to Section 2.2(d),  the Company shall use its best efforts to
keep such Shelf Registration Statement continuously effective,  supplemented and
amended as required by the provisions of Section 2.2(d) to the extent  necessary
to ensure that it is  available  for  resales of  Restricted  Securities  by the
Holders  of  Restricted  Securities,  and to ensure  that it  conforms  with the
requirements of this Agreement,  the Securities Act and the policies,  rules and
regulations  of the  Commission as announced  from time to time, for a period of
one (1) year  from the  Effective  Time or such  longer  period as  required  by
Section  2.2(d)  or  such  shorter  period  that  will  terminate  when  all the
Securities covered by the Shelf  Registration  Statement have been sold pursuant
to  the  Shelf  Registration  Statement  or  otherwise  cease  to be  Restricted
Securities.  Upon the  occurrence  of any  event  that  would  cause  any  Shelf
Registration  Statement  or the  Prospectus  contained  therein (i) to contain a
material  misstatement  or omission or (ii) not to be  effective  and usable for
sale or resale of  Restricted  Securities  during  the period  required  by this
Agreement,  the Company  shall file  promptly an  appropriate  amendment to such
Shelf  Registration   Statement  or  the  related  Prospectus  or  any  document
incorporated  therein by reference,  in the case of clause (i),  correcting  any
such  misstatement  or omission,  and, in the case of either clause (i) or (ii),
use its reasonable  efforts to cause such amendment to be declared effective and
such Registration  Statement and the related Prospectus to become usable for its
intended purpose(s) as soon as practicable thereafter.

      (c) No Holder of Restricted  Securities  may include any of its Restricted
Securities in the Shelf Registration Statement pursuant to this Agreement unless
and until such  Holder  furnishes  to the  Company in  writing,  within ten (10)
Business  Days after receipt of a written  request  therefor,  such  information
specified in Item 507 of Regulation  S-K under the  Securities Act or such other
information as the Company may reasonably request for use in connection with the
Shelf Registration  Statement or Prospectus or preliminary  Prospectus  included
therein and in any  application  to the NASD.  Each Holder as to which the Shelf
Registration  Statement  is being  effected  agrees to furnish  promptly  to the
Company  all  information  required  to  be  disclosed  in  order  to  make  the
information  previously  furnished to the Company by such Holder not  materially
misleading.

      (d) Notwithstanding  anything to the contrary contained herein, if (x) the
Board  determines  in good  faith  that the  registration  and  distribution  of
Restricted  Securities (or the use of such Shelf  Registration  Statement or the
Prospectus  contained  therein)  would  interfere  with any  proposed or pending
material corporate  transaction involving the Company or any of its subsidiaries
or would require  premature  disclosure  thereof or would require the Company to
disclose information that the Company has not otherwise made public and that the
Company  reasonably  determines  is in the best  interests of the Company not to
disclose at such time,  and (y) the Company  notifies the Holders in writing not
later than three (3) days following such determination  (such notice a "Blackout
Notice"),  the Company may (A)  postpone  the filing of such Shelf  Registration
Statement or (B) allow such Shelf Registration Statement to fail to be effective
and usable or elect that such Shelf  Registration  Statement not be usable for a
reasonable  period of time, but not in excess of 30 days (a "Blackout  Period");
provided,  however,  that the aggregate  number of days included in all Blackout
Periods  shall not  exceed 90 during  any  consecutive  12

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<PAGE>

months and shall not exceed 150 during the period specified in Section 2.2(b) of
this Agreement;  and provided,  further,  that the period referred to in Section
2.2(b) during which the Shelf Registration Statement is required to be effective
and usable  shall be extended by the  aggregate  number of days during which the
Shelf  Registration  Statement  was not  effective  or  usable  pursuant  to the
foregoing provisions.

      2.3   PIGGYBACK REGISTRATION.

      (a) At any time that the Company  proposes to file a Company  Registration
Statement within three (3) years from the date hereof, plus the aggregate number
of days during  which the Shelf  Registration  Statement  was not  effective  or
usable  pursuant to Section  2.2(d),  the Company shall give the Holders written
notice  of its  intention  to do so and of the  intended  method  of  sale  (the
"Registration  Notice") within a reasonable time prior to the anticipated filing
date of the Company Registration  Statement effecting such Company Registration.
Each Holder may request  inclusion of any Restricted  Securities in such Company
Registration  by delivering to the Company,  within ten (10) Business Days after
receipt of the Registration  Notice,  a written notice (the "Piggyback  Notice")
stating the number of  Restricted  Securities  proposed to be included  and that
such shares are to be included  in any  underwriting  only on the same terms and
conditions  as  the  shares  of  Common  Stock   otherwise  being  sold  through
underwriters under such Company  Registration  Statement.  The Company shall use
its best efforts to cause all Restricted  Securities  specified in the Piggyback
Notice to be  included  in the Company  Registration  Statement  and any related
offering,  all to the extent requisite to permit the sale by the Holders of such
Restricted  Securities in accordance  with the method of sale  applicable to the
other shares of Common Stock  included in such Company  Registration  Statement;
provided,  however,  that if, at any time  after  giving  written  notice of its
intention  to register any  securities  and prior to the  effective  date of the
Company Registration  Statement filed in connection with such registration,  the
Company shall determine for any reason not to register or to delay  registration
of such  securities,  the Company may, at its election,  give written  notice of
such determination to each Holder of Restricted Securities and, thereupon:

            (i)  in the  case  of a  determination  not to  register,  shall  be
relieved of its obligation to register any  Restricted  Securities in connection
with such  registration  (but not from its  obligation  to pay the  Registration
Expenses in connection therewith), and

            (ii) in the case of a delay in  registering,  shall be  permitted to
delay registering any Restricted  Securities for the same period as the delay in
registering such other securities.

      (b) The Company's obligation to include Restricted Securities in a Company
Registration  Statement  pursuant  to  Section  2.3(a)  shall be  subject to the
following limitations:

            (i) The Company  shall not be  obligated  to include any  Restricted
Securities in a registration statement filed on Form S-4, Form S-8 or such other
similar successor forms then in effect under the Securities Act.

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<PAGE>

            (ii) If a Company  Registration  Statement  involves an underwritten
offering and the managing  underwriter  advises the Company in writing  that, in
its opinion, the number of the Restricted Securities requested to be included in
such Company Registration Statement exceeds the number which can be sold in such
offering without adversely affecting the offering,  the Company will not include
any Restricted Securities in such Company Registration  Statement, or if some of
the requested Restricted Securities can be included in such Company Registration
Statement,  the Company will only include such number of  Restricted  Securities
which the Company is so advised can be sold in such offering  without  adversely
affecting the offering, determined as follows:

            (A) first, all securities proposed by the Company to be sold for its
      own account shall be included in the Company Registration Statement, and

            (B) second,  any Restricted  Securities  requested to be included in
      such  registration on a pari passu basis with any other  securities of the
      Company which have been afforded  registration rights by the Company as of
      the date hereof, or pursuant to the Private Placement.

            (iii) The  Company  shall not be  obligated  to  include  Restricted
Securities in more than two (2) Company Registration Statement(s).

      (c) No Holder of Restricted  Securities  may include any of its Restricted
Securities  in the Company  Registration  Statement  pursuant to this  Agreement
unless and until such Holder  furnishes  to the  Company in writing,  within ten
(10) Business Days after receipt of a written request therefor, such information
specified in Item 507 of Regulation  S-K under the  Securities Act or such other
information as the Company may reasonably request for use in connection with the
Company Registration  Statement or Prospectus or preliminary Prospectus included
therein and in any  application to the NASD. Each Holder as to which the Company
Registration  Statement  is being  effected  agrees to furnish  promptly  to the
Company  all  information  required  to  be  disclosed  in  order  to  make  all
information  previously  furnished to the Company by such Holder not  materially
misleading.

      2.4 REGISTRATION PROCEDURES. In connection with any Registration Statement
and any  Prospectus  required by this  Agreement to permit the sale or resale of
Restricted Securities, the Company shall:

      (a)   prepare  and  file  with  the   Commission   such   amendments   and
post-effective  amendments to such Registration Statement as may be necessary to
keep such Registration Statement effective (i) if such Registration Statement is
a Company Registration Statement,  until the earlier of such time as all of such
securities  have been  disposed of in  accordance  with the intended  methods of
disposition  by the  seller  or  sellers  thereof  set  forth  in  such  Company
Registration  Statement  or  (ii)  if  such  Registration  Statement  is a Shelf
Registration  Statement,  for the applicable  period set forth in Section 2.2(b)
herein;  cause the  Prospectus  to be  supplemented  by any required  Prospectus
supplement,  and as so  supplemented  to be filed pursuant to Rule 424 under the
Securities Act, and to comply fully with the applicable  provisions of Rules 424
and 430A, as

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<PAGE>

applicable,  under the Securities  Act in a timely  manner;  and comply with the
provisions  of  the  Securities  Act  with  respect  to the  disposition  of all
securities  covered by such Registration  Statement during the applicable period
in accordance with the intended method or methods of distribution by the sellers
thereof  set  forth  in  such  Registration   Statement  or  supplement  or  the
Prospectus;

      (b) promptly  (and in respect of events  covered by clause (i) hereof,  on
the same day as the Company shall receive  notice of  effectiveness)  advise the
Holders  covered  by such  Registration  Statement  and,  if  requested  by such
Persons,  confirm  such  advice  in  writing,  (i)  when the  Prospectus  or any
Prospectus  supplement or post-effective  amendment has been filed, and when the
same  has  become  effective,   (ii)  of  any  request  by  the  Commission  for
post-effective  amendments  to such  Registration  Statement  or  post-effective
amendments  to such  Registration  Statement  or  post-effective  amendments  or
supplements to the Prospectus or for additional  information  relating  thereto,
(iii) of the  issuance  by the  Commission  of any  stop  order  suspending  the
effectiveness of any such Registration  Statement under the Securities Act or of
the suspension by any state  securities  commission of the  qualification of the
Restricted  Securities  for  offering  or  sale  in  any  jurisdiction,  or  the
initiation of any proceeding for any of the preceding purposes,  and (iv) of the
existence of any fact or the  happening of any event that makes any statement of
a material fact made in any such Registration Statement, the related Prospectus,
any amendment or supplement thereto,  or any document  incorporated by reference
therein  untrue,  or that  requires the making of any additions to or changes in
any such Registration  Statement or the related  Prospectus in order to make the
statements therein not misleading. If at any time the Commission shall issue any
stop order suspending the effectiveness of such Registration  Statement,  or any
state securities  commission or other regulatory  authority shall issue an order
suspending the  qualification or exemption from  qualification of the Restricted
Securities  under state  securities or Blue Sky laws,  the Company shall use its
reasonable  efforts  to obtain  the  withdrawal  or lifting of such order at the
earliest possible time;

      (c) promptly  furnish to each Holder of Restricted  Securities  covered by
any Registration  Statement,  and each  underwriter,  if any, without charge, at
least one conformed copy of any Registration  Statement, as first filed with the
Commission,  and of each amendment thereto, including all documents incorporated
by reference therein and all exhibits (including exhibits  incorporated  therein
by reference) and any related correspondence between the Company and its counsel
or  accountants  and the  Commission or staff of the  Commission  and such other
documents as such Holder may reasonably request;

      (d) deliver to each Holder covered by any Registration Statement, and each
underwriter, if any, without charge, as many copies of the Prospectus (including
each  preliminary  prospectus)  and any amendment or supplement  thereto as such
person reasonably may request;

      (e)  enter  into  such  customary  agreements  and  take  all  such  other
reasonable action in connection  therewith (including those reasonably requested
by the  selling  Holders or the  underwriter(s),  if any)  required  in order to
expedite or facilitate the disposition of such Restricted Securities pursuant to
such  Registration  Statement,  including,  but  not  limited  to,  dispositions
pursuant to an underwritten registration, and in such connection:

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            (i) make such  representations and warranties to the selling Holders
and underwriter(s), if any, in form, substance and scope as are customarily made
by issuers to underwriters in  underwritten  offerings  (whether or not sales of
securities   pursuant  to  such   Registration   Statement   are  to  be  to  an
underwriter(s)) and confirm the same if and when requested;

            (ii) obtain  opinions of counsel to the Company  (which  counsel and
opinions, in form and substance, shall be reasonably satisfactory to the selling
Holders and the underwriter(s),  if any, and their respective counsel) addressed
to each selling Holder and underwriter, if any, covering the matters customarily
covered in opinions requested in underwritten offerings (whether or not sales of
securities  pursuant  to  such  Registration  Statement  are  to be  made  to an
underwriter(s))  and  dated  the  date  of  effectiveness  of  any  Registration
Statement (and, in the case of any underwritten  sale of securities  pursuant to
such Registration  Statement,  each closing date of sales to the  underwriter(s)
pursuant thereto);

            (iii) use  reasonable  efforts to obtain  comfort  letters dated the
date of  effectiveness  of any  Registration  Statement (and, in the case of any
underwritten sale of securities  pursuant to such Registration  Statement,  each
closing  date  of  sales  to  the  underwriter(s)  pursuant  thereto)  from  the
independent  certified  public  accountants  of the  Company  addressed  to each
selling Holder and underwriter, if any, such letters to be in customary form and
covering  matters  of  the  type  customarily  covered  in  comfort  letters  in
connection  with  underwritten  offerings  (whether  or not sales of  securities
pursuant to such Registration Statement are to be made to an underwriter(s));

            (iv) provide for the  indemnification  provisions  and procedures of
Section 2.8 hereof with respect to selling  Holders and the  underwriter(s),  if
any, and;

            (v) deliver such  documents  and  certificates  as may be reasonably
requested by the selling  Holders or the  underwriter(s),  if any, and which are
customarily  delivered  in  underwritten  offerings  (whether  of not  sales  of
securities  pursuant  to  such  Registration  Statement  are  to be  made  to an
underwriter(s),  with such  documents and  certificates  to be dated the date of
effectiveness of any Registration Statement.

      The  actions  required  by clauses  (i) through (v) above shall be done at
each closing under such underwriting or similar agreement,  as and to the extent
required  thereunder,  and if at any time the  representations and warranties of
the Company  contemplated in clause (i) above cease to be true and correct,  the
Company  shall so advise the  underwriter(s),  if any, and each  selling  Holder
promptly,  and,  if  requested  by such  Person,  shall  confirm  such advice in
writing;

      (f) prior to any public offering of Restricted Securities,  cooperate with
the selling Holders, the underwriter(s), if any, and their respective counsel in
connection with the registration and qualification of the Restricted  Securities
under the securities or Blue Sky laws of such U.S.  jurisdictions as the selling
Holders or underwriter(s), if any, may reasonably request in writing by the time
any Registration  Statement is declared effective by the Commission,  and do any
and all other acts or filings  necessary or advisable to enable  disposition  in
such U.S. jurisdictions of the

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Restricted  Securities  covered by any  Registration  Statement and to file such
consents to service of process or other  documents  as may be necessary in order
to effect  such  registration  or  qualification;  provided,  however,  that the
Company shall not be required to register or qualify as a foreign corporation in
any jurisdiction  where it is not then so qualified or as a dealer in securities
in any  jurisdiction  where it would not  otherwise  be  required to register or
qualify but for this Section 2.4, or to take any action that would subject it to
the  general  service  of  process  in  suits  or to  general  taxation,  in any
jurisdiction where it is not then so subject;

      (g) in connection with any sale of Restricted  Securities that will result
in such  securities no longer being  Restricted  Securities,  cooperate with the
selling  Holders  and the  underwriter(s),  if any,  to  facilitate  the  timely
preparation and delivery of certificates  representing  Restricted Securities to
be sold and not  bearing any  restrictive  legends;  and enable such  Restricted
Securities  to be in such  denominations  and  registered  in such  names as the
Holders or the  underwriter(s),  if any,  may request at least two (2)  Business
Days prior to any sale of Restricted Securities made by such underwriters;

      (h) use its reasonable  efforts to cause the disposition of the Restricted
Securities  covered  by any  Registration  Statement  to be  registered  with or
approved  by such other U.S.  governmental  agencies  or  authorities  as may be
necessary to enable the seller or sellers thereof or the underwriter(s), if any,
to consummate the  disposition  of such  Restricted  Securities,  subject to the
proviso contained in Section 2.2(f);

      (i) if any fact or event  contemplated  by Section  2.4(b)  shall exist or
have  occurred,   prepare  a  supplement  or  post-effective  amendment  to  any
Registration  Statement  or  related  Prospectus  or any  document  incorporated
therein by reference or file any other required  document so that, as thereafter
delivered to the Purchaser of Restricted  Securities,  the  Prospectus  will not
contain an untrue  statement  of a material  fact or omit to state any  material
fact necessary to make the statement therein not misleading;

      (j)  cooperate  and  assist  in  the  performance  of  any  due  diligence
investigation   by  any  underwriter   (including  any  "qualified   independent
underwriter")  that is required to be retained in accordance  with the rules and
regulations  of  the  NASD,  and  use  its  reasonable   efforts  to  cause  any
Registration   Statement  to  become   effective   and  approved  by  such  U.S.
governmental  agencies or  authorities as may be necessary to enable the Holders
selling  Restricted  Securities to consummate the disposition of such Restricted
Securities;

      (k) otherwise  use its  reasonable  efforts to comply with all  applicable
rules and  regulations of the  Commission,  and make generally  available to its
security  holders  with  regard  to  such  Registration  Statement,  as  soon as
practicable,  a consolidated earnings statement meeting the requirements of Rule
158 (which need not be audited) for the  twelve-month  period (i)  commencing at
the end of any fiscal  quarter in which  Restricted  Securities  are sold to the
underwriter in a firm or best efforts underwritten  offering or (ii) if not sold
to an  underwriter  in such an offering,  beginning  with the first month of the
Company's  first  fiscal  quarter  commencing  after the  effective  date of any
Registration Statement;

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<PAGE>

      (l)   provide a CUSIP  number for all  Restricted  Securities  not later
than the effective date of any Registration Statement;

      (m) use its best  efforts to list,  not later than the  effective  date of
such  Registration   Statement,   all  Restricted  Securities  covered  by  such
Registration  Statement on the NASD OTC  Electronic  Bulletin Board or any other
trading  market on which any Common  Stock of the Company are then  admitted for
trading; and

      (n) provide promptly to each Holder covered by any Registration  Statement
upon  request  each  document  filed  with  the   Commission   pursuant  to  the
requirements of Section 12 and Section 14 of the Exchange Act.

      Each Holder agrees by  acquisition  of a Restricted  Security  that,  upon
receipt of any notice from the Company of the  existence of any fact of the kind
described in Section  2.4(b)(iv) or the commencement of a Blackout Period,  such
Holder will forthwith discontinue  disposition of Restricted Securities pursuant
to any  Registration  Statement until such Holder's receipt of the copies of the
supplemented or amended  Prospectus  contemplated by Section 2.4(i), or until it
is advised in writing,  in accordance with the notice  provisions of Section 3.3
herein (the  "Advice"),  by the Company  that the use of the  Prospectus  may be
resumed, and has received copies of any additional or supplemental fillings that
are incorporated by reference in the Prospectus.  If so directed by the Company,
each Holder will deliver to the Company all copies,  other than  permanent  file
copies,  then in such  Holder's  possession,  of the  Prospectus  covering  such
Restricted Securities that was current at the time of receipt of such notice. In
the event the Company shall give any such notice,  the time period regarding the
effectiveness  of the Shelf  Registration  Statement set forth in Section 2.2(b)
shall be extended by the number of days during the period from and including the
date  of the  giving  of such  notice  pursuant  to  Section  2.4(b)(iv)  or the
commencement  of a Blackout  Period to and  including the date when each selling
Holder covered by such Registration  Statement shall have received the copies of
the supplemented or amended  Prospectus  contemplated by Section 2.4(i) or shall
have  received (in  accordance  with the notice  provisions  of Section 3.3) the
Advice.

      2.5  PREPARATION;   REASONABLE  INVESTIGATION.   In  connection  with  the
preparation and filing of each Registration  Statement under the Securities Act,
the Company will give the Holders of Restricted Securities registered under such
Registration Statement, their underwriter,  if any, and their respective counsel
and  accountants,  the  opportunity to  participate  in the  preparation of such
Registration  Statement,  each  prospectus  included  therein  or filed with the
Commission, and each amendment thereof or supplement thereto, and will give each
of them access to its books and records  and such  opportunities  to discuss the
business,  finances  and accounts of the Company and its  subsidiaries  with its
officers,  directors and the independent  public  accountants who have certified
its financial  statements as shall be necessary,  in the opinion of such Holders
and such underwriters' respective counsel, to conduct a reasonable investigation
within the meaning of the Securities Act.

      2.6 CERTAIN RIGHTS OF HOLDERS.  The Company will not file any registration
statement  under the  Securities  Act which  refers to any Holder of  Restricted
Securities by name or otherwise without the prior approval of such Holder, which
consent shall not be unreasonably withheld or

                                       10

<PAGE>

delayed.

      2.7   REGISTRATION EXPENSES.

      (a) All expenses  incident to the Company's  performance  of or compliance
with  this  Agreement  will be borne by the  Company,  regardless  of  whether a
Registration Statement becomes effective,  including without limitation: (i) all
registration and filing fees and expenses  (including filings made with the NASD
and reasonable counsel fees in connection  therewith);  (ii) all reasonable fees
and  expenses  of  compliance  with  federal  securities  and state  Blue Sky or
securities  laws  (including all reasonable  fees and expenses of one counsel to
the underwriter(s) in any underwriting) in connection with compliance with state
Blue Sky or  securities  laws for all  states in the  United  States;  (iii) all
expenses of printing,  messenger and delivery services and telephone calls; (iv)
all fees and  disbursements  of counsel  for the  Company;  and (v) all fees and
disbursements  of  independent  certified  public  accountants  of  the  Company
(including the expenses of any special audit and comfort letters  required by or
incident to such  performance),  but  excluding  from this  paragraph,  fees and
expenses of counsel to the  underwriter(s),  if any, unless  otherwise set forth
herein.

      (b) In addition,  in connection with the filing of the Shelf  Registration
Statement required to be filed by this Agreement, the Company will reimburse the
Holders of the  Restricted  Securities  being  registered  pursuant to any Shelf
Registration  Statement for the reasonable  fees and  disbursements  of not more
than one counsel to review such Registration Statement.

      (c) Notwithstanding the foregoing, the Company will not be responsible for
any  underwriting  discounts,  commissions or fees  attributable  to the sale of
Restricted  Securities or any legal fees or  disbursements  (other than any such
fees or disbursements  relating to Blue Sky compliance or otherwise as set forth
under  Section  2.7(a))  incurred  by any  underwriter(s)  in  any  underwritten
offering if the underwriter(s) participates in such underwritten offering at the
request of the Holders of Restricted Securities,  or any transfer taxes that may
be imposed in connection with a sale or transfer of Restricted Securities.

      (d)  The  Company  shall,  in  any  event,   bear  its  internal  expenses
(including,  without  limitation,  all salaries and expenses of its officers and
employees  performing  legal or accounting  duties),  the expenses of any annual
audit  and the fees and  expenses  of any  Person,  including  special  experts,
retained by the Company.

      2.8   INDEMNIFICATION; CONTRIBUTION.

      (a) The Company  agrees to  indemnify  and hold  harmless  (i) each Holder
covered by any Registration  Statement,  (ii) each other Person who participates
as an underwriter in the offering or sale of such securities, (iii) each person,
if any, who controls  (within the meaning of Section 15 of the Securities Act or
Section  20 of the  Exchange  Act) any such  Holder or  underwriter  (any of the
persons  referred to in this clause  (iii)  being  hereinafter  referred to as a
"controlling  person") and (iv) the respective  officers,  directors,  partners,
employees,  representatives  and agents of any such Holder or underwriter or any
controlling  person (any person  referred to in clause (i), (ii),  (iii) or (iv)

                                       11

<PAGE>

may  hereinafter  be referred  to as an  "indemnified  Person"),  to the fullest
extent  lawful,  from  and  against  any  and  all  losses,   claims,   damages,
liabilities, judgments or expenses, joint or several (or actions or proceedings,
whether commenced or threatened,  in respect thereof) (collectively,  "Claims"),
to which such  indemnified  Person may become subject under either Section 15 of
the  Securities  Act or Section 20 of the Exchange Act or otherwise,  insofar as
such  Claims  arise  out of or are  based  upon,  or are  caused  by any  untrue
statement  or alleged  untrue  statement  of a material  fact  contained  in any
Registration  Statement or Prospectus (or any amendment or supplement  thereto),
or any omission or alleged omission to state therein a material fact required to
be stated therein or necessary to make the statements therein not misleading, or
a violation by the Company of the Securities Act or any state securities law, or
any  rule or  regulation  promulgated  under  the  Securities  Act or any  state
securities law, or any other law applicable to the Company  relating to any such
registration or qualification,  except insofar as such losses, claims,  damages,
liabilities,  judgments  or expenses  of any such  indemnified  Person;  (x) are
caused by any such untrue  statement or omission or alleged untrue  statement or
omission  that is based upon  information  relating to such  indemnified  Person
furnished  in writing to the Company by or on behalf of any of such  indemnified
Person  expressly  for  use  therein;   (y)  with  respect  to  the  preliminary
Prospectus, result from the fact that such Holder sold Securities to a person to
whom there was not sent or given,  at or prior to the  written  confirmation  of
such sale, a copy of the Prospectus, as amended or supplemented,  if the Company
shall have previously furnished copies thereof to such Holder in accordance with
this  Agreement  and said  Prospectus,  as amended or  supplemented,  would have
corrected such untrue statement or omission; or (z) as a result of the use by an
indemnified  Person of any Prospectus when, upon receipt of a Blackout Notice or
a notice from the Company of the existence of any fact of the kind  described in
Section  2.4(b)(iv),  the  indemnified  Person  or the  related  Holder  was not
permitted  to do so.  Such  indemnity  shall  remain in full  force  and  effect
regardless of any investigation  made by or on behalf of any indemnified  Person
and shall survive the transfer of such securities by such Holder.

      In case any  action  shall  be  brought  or  asserted  against  any of the
indemnified  Persons with respect to which  indemnity may be sought  against the
Company,  such  indemnified  Person  shall  promptly  notify the Company and the
Company shall assume the defense thereof. Such indemnified Person shall have the
right to employ  separate  counsel in any such action and to  participate in the
defense  thereof,  but the fees and  expenses  of such  counsel  shall be at the
expense of the  indemnified  Person  unless (i) the  employment  of such counsel
shall have been  specifically  authorized  in writing by the  Company,  (ii) the
Company shall have failed to assume the defense and employ  counsel or (iii) the
named parties to any such action  (including any implied  parties)  include both
the  indemnified  Person and the Company and the  indemnified  Person shall have
been  advised  in  writing  by its  counsel  that there may be one or more legal
defenses  available  to it  which  are  different  from or  additional  to those
available to the Company (in which case the Company  shall not have the right to
assume the defense of such action on behalf of the indemnified Person), it being
understood,  however, that the Company shall not, in connection with such action
or similar or related  actions or  proceedings  arising out of the same  general
allegations or circumstances,  be liable for the reasonable fees and expenses of
more than one separate firm of attorneys  (in addition to any local  counsel) at
any time for all the indemnified Persons,  which firm shall be (x) designated by
such  indemnified  Persons and (y) reasonably  satisfactory to the Company.  The
Company shall not be liable for any  settlement of any such action or proceeding
effected without the Company's

                                       12

<PAGE>

prior written consent, which consent shall not be withheld unreasonably, and the
Company  agrees to indemnify and hold harmless any  indemnified  Person from and
against any loss, claim, damage, liability, judgment or expense by reason of any
settlement of any action effected with the written  consent of the Company.  The
Company shall not, without the prior written consent of each indemnified Person,
settle or compromise or consent to the entry of judgment on or otherwise seek to
terminate any pending or threatened action,  claim,  litigation or proceeding in
respect  of  which  indemnification  or  contribution  may be  sought  hereunder
(whether  or not  any  indemnified  Person  is a  party  thereto),  unless  such
settlement, compromise, consent or termination includes an unconditional release
of each indemnified Person from all liability arising out of such action,  claim
litigation or proceeding.

      (b) Each  Holder of  Restricted  Securities  covered  by any  Registration
Statement agrees,  severally and not jointly, to indemnify and hold harmless the
Company  and its  directors,  officers  and any person  controlling  (within the
meaning of Section 15 of the  Securities  Act or Section 20 of the Exchange Act)
the  Company,  and the  respective  officers,  directors,  partners,  employees,
representatives  and agents of each person,  to the same extent as the foregoing
indemnity from the Company to each of the indemnified Persons, but only (i) with
respect to actions  based on  information  relating to such Holder  furnished in
writing by or on behalf of such  Holder  expressly  for use in any  Registration
Statement or Prospectus,  and (ii) to the extent of the gross proceeds,  if any,
received  by such  Purchaser  from the sale or other  disposition  of his or its
Restricted Securities covered by such Registration Statement. In case any action
or proceeding  shall be brought against the Company or its directors or officers
or any such  controlling  person in  respect  of which  indemnity  may be sought
against a Holder of Restricted Securities covered by any Registration Statement,
such Holder shall have the rights and duties given the Company in Section 2.8(a)
(except  that the Holder  may but shall not be  required  to assume the  defense
thereof),  and the Company or its  directors  or  officers  or such  controlling
person shall have the rights and duties given to each Holder by Section 2.8(a).

      (c) If the indemnification provided for in this Section 2.8 is unavailable
to an  indemnified  party under  Section  2.8(a) or (b) (other than by reason of
exceptions  provided  in those  Sections)  in  respect  of any  losses,  claims,
damages,  liabilities,  judgments  or expenses  referred  to therein,  then each
applicable  indemnifying  party (in the case of the  Holders  severally  and not
jointly),  in lieu of indemnifying such indemnified  party,  shall contribute to
the amount paid or payable by such indemnified party as a result of such losses,
claims damages, liabilities,  judgments or expenses (i) in such proportion as is
appropriate to reflect the relative  benefits received by the Company on the one
hand and the Holder on the other hand from sale of Restricted Securities or (ii)
if such  allocation  provided by clause (i) above is not permitted by applicable
law, in such  proportion  as is  appropriate  to reflect  not only the  relative
benefits  referred  to in clause  (i) above but also the  relative  fault of the
Company and such Holder in connection  with the  statements  or omissions  which
resulted in such losses, claims, damages, liabilities, judgments or expenses, as
well as any other relevant equitable  considerations.  The relative fault of the
Company on the one hand and of such Holder on the other shall be  determined  by
reference to, among other things, whether the untrue or alleged untrue statement
of a material fact or the omission or alleged  omission to state a material fact
relates to information supplied by the Company or by such Holder and the parties
relative intent, knowledge,  access to information and opportunity to correct or

                                       13

<PAGE>

prevent such  statement  or omission.  The amount paid to a party as a result of
the losses,  claims,  damages,  liabilities  judgments and expenses  referred to
above shall be deemed to include,  subject to the  limitations  set forth in the
second  paragraph  of  Section  2.8(a),  any  legal  or other  fees or  expenses
reasonably  incurred by such party in connection with investigating or defending
any action or claim.

      The  Company  and each  Holder of  Restricted  Securities  covered  by any
Registration  Statement  agree  that it  would  not be  just  and  equitable  if
contribution  pursuant  to this  Section  2.8(c)  were  determined  by pro  rata
allocation  (even if the Holders were treated as one entity for such purpose) or
by any other method of allocation which does not take into account the equitable
considerations   referred   to   in   the   immediately   preceding   paragraph.
Notwithstanding the provisions of this Section 2.8(c) no Holder (and none of its
related indemnified Persons) shall be required to contribute,  in the aggregate,
any  amount in excess of the  amount  by which  the  dollar  amount of  proceeds
received by such Holder upon the sale of the Restricted  Securities  exceeds the
amount of any damages  which such Holder has  otherwise  been required to pay by
reason of such  untrue  statement  or omission  or alleged  omission.  No person
guilty of fraudulent  misrepresentations (within the meaning of Section 11(f) of
the Securities  Act) shall be entitled to  contribution  from any person who was
not guilty of such fraudulent misrepresentation.

      The indemnity,  and contribution  provisions contained in this Section 2.8
are in addition to any  liability  which the  indemnifying  person may otherwise
have to the indemnified persons referred to above.

      2.9 PARTICIPATION IN UNDERWRITTEN REGISTRATIONS. No Holder may participate
in any underwritten registration hereunder unless such Holder (a) agrees to sell
such Holder's  Restricted  Securities on the basis provided in any  underwriting
arrangements  approved  by  the  Persons  entitled  hereunder  to  approve  such
arrangements  and (b)  completes  and  executes all  reasonable  questionnaires,
powers of attorney,  indemnities,  underwriting agreements,  lock-up letters and
other documents required under the terms of such underwriting arrangements.

      2.10  SELECTION  OF  UNDERWRITERS.  The Holders of  Restricted  Securities
covered  by  any  Registration  Statement  who  desire  to do so may  sell  such
Restricted  Securities in an  underwritten  offering.  In any such  underwritten
offering,  the investment  banker or investment  bankers and manager or managers
that will  administer the offering will be selected by the Holders of a majority
of the Restricted  Securities  included in such offering if such registration is
pursuant  to the  Shelf  Registration  Statement,  and by the  Company  if  such
registration is pursuant to a Company Registration Statement; provided, however,
that such investment bankers and managers must be reasonably satisfactory to the
Company or the Holders,  respectively. The Company hereby agrees that Fahnestock
& Co. Inc. is  acceptable  for  purposes  hereof.  Such  investment  bankers and
managers are referred to herein as the "underwriters".

                                       14

<PAGE>

                                    ARTICLE 3
                                  MISCELLANEOUS

      3.1 ENTIRE AGREEMENT. This Agreement, together with the Financial Advisory
and Investment Banking  Agreement,  constitutes the entire agreement between the
parties  with  respect to the subject  matter  hereof and  supersedes  all prior
agreement and  understandings,  both oral and written,  between the parties with
respect to the subject matter hereof.

      3.2  SUCCESSORS AND ASSIGNS AND HEIRS.  This Agreement  shall inure to the
benefit of and be binding upon the  successors  and assigns and heirs of each of
the parties,  including  without  limitation and without the need for an express
assignment, subsequent Holders of Restricted Securities; provided, however, that
this Agreement  shall not inure to the benefit of or be binding upon a successor
or assign of a Holder unless and to the extent such successor or assign or heirs
acquired Restricted Securities from such Holder at a time when such Holder could
not transfer such Restricted  Securities pursuant to any Registration  Statement
or pursuant to Rule 144(k) under the  Securities Act as  contemplated  by clause
(ii) of the definition of Restricted Securities.

      3.3. NOTICES.  All notices and other communications given or made pursuant
hereto or pursuant to any other  agreement among the parties,  unless  otherwise
specified,  shall be in  writing  and shall be deemed to have been duly given or
made if sent by telecopy (with confirmation in writing), delivered personally or
by overnight  courier or sent by registered or certified mail (postage  prepaid,
return  receipt  requested)  to the parties at the telecopy  number,  if any, or
address set forth below or at such other  addresses as shall be furnished by the
parties by like notice.  Notices  sent by  telecopier  shall be  effective  when
receipt is acknowledged,  notices  delivered  personally or by overnight courier
shall be effective upon receipt and notices sent by registered or certified mail
shall be effective three days after mailing:

            if to a Holder:     to such  Holder at the  address set forth on the
                                records of the  Company as the record  owners of
                                the Common Stock

            with a copy to:     Fahnestock & Co. Inc.
                                125 Broad Street
                                New York, New York 10004
                                Attention: Frank (Kee) Colen

            if to the Company:  Senesco Technologies, Inc.
                                34 Chambers Street
                                Princeton, New Jersey  08542
                                Telephone Number:  (609) 252-0680
                                Fax:  (609) 252-0049
                                Attention: Steven Katz, President,
                                           Chief Operating Officer and Treasurer

                                       15

<PAGE>

            with copies to:     Buchanan Ingersoll Professional Corporation
                                650 College Road East
                                Princeton, New Jersey 08540
                                Telephone Number:  (609) 987-6800
                                Fax:  (609) 520-0360
                                Attention:  David J. Sorin, Esq.

      3.4 HEADINGS. The headings contained in this Agreement are for convenience
only and shall not affect the meaning or interpretation of this Agreement.

      3.5  COUNTERPARTS.  This  Agreement  may  be  executed  in any  number  of
counterparts,  each of which shall be deemed to be an original  and all of which
together shall be deemed to be one and the same instrument.

      3.6 APPLICABLE  LAW. This Agreement  shall be governed by and construed in
accordance with the internal laws of the State of New York without giving effect
to  the  choice  law  provisions,   and  the  Company  hereby  consents  to  the
jurisdiction  of the courts of the State of New York for any matters arising out
of this Agreement.

      3.7 SPECIFIC ENFORCEMENT. Each party hereto acknowledges that the remedies
at law of the other parties for a breach or threatened  breach of this Agreement
would be  inadequate,  and,  in  recognition  of this  fact,  any  party to this
Agreement, without posting any bond, and in addition to all other remedies which
may be available,  shall be entitled to obtain  equitable  relief in the form of
specific  performance,  a temporary  restraining order, a temporary to permanent
injunction or any other equitable remedy which may then be available.

      3.8 AMENDMENT  AND WAIVERS.  The  provisions of this  Agreement may not be
amended, modified or supplemented, and waivers or consents to or departures from
the  provisions  hereof may not be given  unless the  Company has  obtained  the
written  consent  of the  Holders  of a majority  of the  Restricted  Securities
affected  thereby.  Except  for  Common  Stock  sold  pursuant  to  the  Private
Placement,  it is hereby understood and agreed to by the parties hereto that the
Company may only grant  registration  rights to such other purchasers of capital
stock  of the  Company  which  are  junior  to the  registration  rights  of the
Purchaser hereunder.

      3.9 ELIGIBILITY FOR FORM S-3. The Company represents and warrants that, as
of the  date  hereof,  it  meets  the  requirements  for the use of Form S-3 for
registration  of the sale by the Purchaser of the Restricted  Securities and the
Company  has filed all  reports  required  to be filed by the  Company  with the
Commission  in a timely manner so as to obtain such  eligibility  for the use of
Form S-3. The Company  shall use its best efforts to meet the  requirements  for
use of Form S-3 for  registration of the sale by the Purchaser of the Restricted
Securities  and the Company  shall file all reports  required to be filed by the
Company with the Commission in a timely manner so as to maintain eligibility for
the use of Form S-3.

      3.9  ELIGIBILITY  UNDER RULE 144.  With a view to making  available to the
Purchaser the benefits of Rule 144  promulgated  under the Securities Act or any
other similar rule or regulation

                                       16

<PAGE>

of the Commission  that may at any time permit the Purchaser to sell  securities
of the Company to the public  without  registration  ("Rule  144"),  the Company
agrees to:

      a.    make and keep  public  information  available,  as those terms are
understood and defined in Rule 144;

      b. file with the  Commission  in a timely  manner  all  reports  and other
documents  required of the Company under the Exchange Act so long as the Company
remains  subject to such  requirements  and the filing of such reports and other
documents is required for the applicable provisions of Rule 144; and

      c.  furnish to the  Purchaser  so long as the  Purchaser  owns  Restricted
Securities,  promptly upon request,  (i) a written statement by the Company that
it has complied with the reporting requirements of the Exchange Act, (ii) a copy
of the most  recent  annual or  quarterly  report of the  Company and such other
reports and documents so filed by the Company,  and (iii) such other information
as may be reasonably  requested to permit the investors to sell such  securities
pursuant to Rule 144 without registration.

                                 * * * * * * * *

                                       17

<PAGE>

      IN WITNESS  WHEREOF,  the parties  hereto have caused this Agreement to be
duly  executed by their  respective  authorized  officers as of the day and year
first above written.

                                COMPANY:

                                SENESCO TECHNOLOGIES, INC.

                                By: /s/ Steven Katz
                                    -----------------------------------------
                                    Name: Steven Katz
                                    Title: President, Chief Operating Officer
                                           and Treasurer

                                PURCHASER:

                                FAHNESTOCK & CO. INC.

                                By: /s/ Frank Kee Colen
                                    -----------------------------------------
                                    Name:  Frank Kee Colen
                                    Title: Vice President

                                       18March 30, 2000

Fahnestock & Co. Inc.
125 Broad Street, 16th Floor
New York, NY  10004

Ladies and Gentlemen:

      The undersigned  understands  that Fahnestock & Co. Inc.  ("Fahnestock")
has entered into a Placement Agent Agreement with Senesco Technologies,  Inc.,
a Delaware  corporation (the "Company"),  providing for the private  placement
(the  "Private  Placement")  of shares (the  "Shares")  of common stock of the
Company (the "Common Stock").

      To induce  Fahnestock  to  continue  its  efforts in  connection  with the
Private Placement, the undersigned hereby agrees that, without the prior written
consent of  Fahnestock,  it will not,  during the period  commencing on the date
hereof and ending  upon the  earlier  of: (a)  thirty  (30) days  following  the
effective date of a registration  statement in which the Shares are included; or
(b) nine (9) months  after the final  closing  of the  Private  Placement  (such
earlier date referred to as the "Termination  Date"), (i) offer,  pledge,  sell,
contract to sell,  sell any option or contract to  purchase,  lend or  otherwise
transfer or dispose of,  directly or  indirectly,  any shares of Common Stock or
any securities convertible into or exercisable or exchangeable for Common Stock,
or (ii) enter into any swap or other  arrangement that transfers to another,  in
whole or in part,  any of the economic  consequences  of ownership of the Common
Stock, whether any such transaction  described in clause (i) or (ii) above is to
be settled by  delivery  of Common  Stock or such other  securities,  in cash or
otherwise. The foregoing sentence shall not apply to: (A) the transfer of shares
of Common Stock or other  securities of the Company by the undersigned as a gift
or gifts;  and (B) the transfer of shares of Common Stock or other securities of
the Company by the  undersigned  to its  affiliates,  as such term is defined in
Rule 405 under the  Securities Act of 1933, as amended;  provided,  that, in the
case of clause (A) or (B) above, the  recipient(s),  donee(s) or  transferee(s),
respectively,  agrees in writing as a condition precedent to such issuance, gift
or  transfer  to be  bound by the  terms of this  agreement.  In  addition,  the
undersigned  agrees that,  without the prior written  consent of Fahnestock,  it
will not,  during the period  commencing  on the date hereof and ending upon the
Termination Date, make any demand for or exercise any right with respect to, the
registration of any shares of Common Stock or any security  convertible  into or
exercisable or exchangeable for Common Stock.

                                Very truly yours,

                                ---------------------------------------------
                                (Signature)

                                ---------------------------------------------
                                (Print Name)

                                ---------------------------------------------
                                (Address)

                                ---------------------------------------------
                                (Address)

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