Document:

Exhibit 4.3

CERTIFICATE OF DESIGNATION OF

RIGHTS, REFERENCES AND PRIVILEGES OF

SERIES B CONVERTIBLE PREFERRED STOCK OF

AP EVENT, INC.

To Be Designated

Series B Convertible Preferred Stock

The undersigned DOES HEREBY CERTIFY that the following resolution was duly adopted by the Board of Directors (the “Board of Directors”) of AP Event, Inc., a Nevada corporation (the “Corporation”), at a meeting duly convened and held, at which a quorum was present and acting throughout:

RESOLVED, that pursuant to the authority conferred on the Board of Directors by the Corporation’s Articles of Incorporation, the issuance of a series of preferred stock, par value $0.001 per share, of the Corporation which shall consist of Twenty-Seven Thousand Twenty-Seven (27,027) shares of convertible preferred stock be, and the same hereby are, authorized; and the officers of the Corporation be, and he hereby are, authorized and directed to execute and file with the Secretary of State of the State of Nevada a Certificate of Designation of Preferred Stock of the Corporation fixing the designations, powers, preferences and rights of the shares of such series, and the qualifications, limitations or restrictions thereof (in addition to the designations, powers, preferences and rights, and the qualifications, limitations or restrictions thereof, set forth in the Article of Incorporation which may be applicable to the Corporation’s preferred stock), as follows:

1.            Number of Shares; Designation. A total of 27,027 shares of preferred stock, par value $0.001 per share, of the Corporation are hereby designated as Series B Convertible Preferred Stock (the “Series B Preferred Stock”).

2.            Stated Value.  The Stated Value of the Series B Preferred Stock Shall be $1.00 per share.

3.             Liquidation.

(a)         In the event of a consolidation, merger, reorganization, Change of Control (as defined below), or other business combination of the Corporation with or into any other person or persons, the sale of all or substantially all of the assets of the Corporation, liquidation, dissolution or winding up of the Corporation, whether voluntary or involuntary (a “Liquidation Event”), the holders of the Series B Preferred Stock then outstanding shall be entitled to receive out of the available assets of the Corporation, whether such assets are stated capital or surplus of any nature, an amount on such date equal to the Stated Value, as adjusted, (the “Liquidation Preference”) to be distributed pro rata in accordance with each Holder’s ownership of the Series B Preferred Stock.

(b)        The Corporation shall, no later than the date on which a Liquidation Event occurs, deliver written notice of any Liquidation Event, stating the payment date or dates when and the place or places where the amounts distributable in such circumstances shall be payable, not less than 30 days prior to any payment date stated therein, to each Holder.

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4.          Conversion.

(a)         Right to Convert. Each Holder shall have the right to convert, at any time and from time to time, all or any part of the Series B Preferred Shares held by such Holder into such number of fully paid and non-assessable shares of Common Stock (the “Conversion Shares”) as is determined in accordance with the terms hereof (a “Conversion”).

(b)        Conversion Notice. In order to convert Series B Preferred Shares, a Holder shall send to the Corporation by facsimile transmission, at any time prior to 3:00 p.m., New York time, on the Business Day (as used herein, the term “Business Day” shall mean any day except a Saturday, Sunday or day on which the Federal Reserve Bank of New York, New York is closed in the ordinary course of business) on which such Holder wishes to effect such Conversion (the “Conversion Date”), a notice of conversion in substantially the form attached as Annex I hereto (a “Conversion Notice”), stating the number of Series B Preferred Shares to be converted, and a calculation of the number of shares of Common Stock issuable upon such Conversion in accordance with the rate set forth in paragraph 4(c) below. The Holder shall promptly thereafter send the Conversion Notice and the certificate or certificates being converted to the Corporation. The Corporation shall issue a new certificate for Preferred Shares to the Holder in the event that less than all of the Preferred Shares represented by a certificate are converted; provided, however, that the failure of the Corporation to deliver such new certificate shall not affect the right of the Holder to submit a further Conversion Notice with respect to such Preferred Shares and, in any such case, the Holder shall be deemed to have submitted the original of such new certificate at the time that it submits such further Conversion Notice. Except as otherwise provided herein, upon delivery of a Conversion Notice by a Holder in accordance  with the terms hereof, such Holder shall, as of the applicable Conversion Date, be deemed for all purposes to be the record owner of the Common Stock to which such Conversion Notice relates.

(c)         Conversion Rate. The Holders may, at such Holder’s option, without any further consideration, at any time, elect to convert all or any portion of the Series B Preferred Shares held by such person into sixteen (16) fully paid and nonassessable shares of Common Stock per each Series B Preferred Share converted (the “Conversion Rate”). Upon the event of a liquidation, dissolution, or winding up of the Corporation, the conversion rights of the Series B Preferred Shares shall terminate at the close of business on the last full day preceding the date fixed for the payment of any such amounts distributable on such event to the Holders.

(d)         Delivery of Conversion Shares. The Corporation shall, no later than the close of business on the third (3rd) Business Day following the later of the date on which the Corporation receives a Conversion Notice from a Holder, and the date on which the Corporation receives the related Preferred Shares certificate (such third Business Day, the “Delivery Date”), issue and deliver or cause to be delivered to such Holder the number of Conversion Shares determined pursuant to paragraph 4(c) above.

(e)         Adjustments. The Conversion Rate shall be subject to adjustment from time to time as follows:

(i)          In the event that the Corporation shall (A) pay a dividend or make a distribution, in shares of Common Stock, on any class of Capital Stock of the Corporation (B) split or subdivide its outstanding Common Stock into a greater number of shares, or (C) combine its outstanding Common Stock into a smaller number of shares, then in each such case the Conversion Rate in effect immediately prior thereto shall be adjusted so that the holder of each share of the Series B Preferred Shares thereafter surrendered for conversion shall be entitled to receive the number of shares of Common Stock that such holder would have owned or have been entitled to receive after the occurrence of any of the events described above had such share of the Series B Preferred Shares been converted immediately prior to the occurrence of such event. An adjustment made pursuant to this paragraph 4(e)(i) shall become effective immediately after the close of business on the record date in the case of a dividend or distribution and shall become effective immediately after the close of business on the effective date in the case of such subdivision, split or combination, as the case may be. Any shares of Common Stock issuable in payment of a dividend shall be deemed to have been issued immediately prior to the close of business on the record date for such dividend for purposes of calculating the number of outstanding shares of Common Stock under clause (ii).

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(ii)        No adjustment in the Conversion Rate shall be required unless the adjustment would require an increase or decrease of at least 1% in the Conversion Rate then in effect; provided, however, that any adjustments that by reason of this paragraph 4(e)(ii) are not required to be made shall be carried forward and taken into account in any subsequent adjustment. All calculations under this paragraph 4(e) shall be made to the nearest cent or nearest 1/100th of a share.

(iii)        In the event that, at any time as a result of an adjustment made pursuant to paragraph 4(e)(i) above, the holder thereafter surrendered for conversion shall become entitled to receive any shares of Capital Stock of the Corporation other than shares of the Common Stock, thereafter the number of such other shares so receivable upon conversion of any share of the Series B Preferred Shares shall be subject to adjustment from time to time in a manner and on terms as nearly equivalent as practicable to the provisions with respect to the Common Stock contained in paragraph 4(e)(i) above, and the other provisions of this paragraph 4(e) with respect to the Common Stock shall apply on like terms to any such other shares.

(f)          In case of any reclassification of the Common Stock (other than in a transaction to which paragraph 4(e)(i) applies), any consolidation of the Corporation with, or merger of the Corporation into, any other entity, any merger of another entity into the Corporation (other than a merger that does not result in any reclassification, conversion, exchange or cancellation of outstanding shares of Common Stock of the Corporation), Change of Control (as defined below), any sale or transfer of all or substantially all of the assets of the Corporation or any compulsory share exchange, pursuant to which share exchange the Common Stock is converted into other securities, cash or other property, then lawful provision shall be made as part of the terms of such transaction whereby the holder of each share of the Series B Preferred Shares then outstanding shall have the right thereafter, during the period such share shall be convertible, to convert such share only into the kind and amount of securities, cash  and other property receivable upon the reclassification, consolidation, merger, sale, transfer, Change of Control, or share exchange by a holder of the number of shares of Common Stock of the Corporation into which a share of the Series might have been converted immediately prior to the reclassification, failed to exercise rights of election, if any, as to the kind or amount of securities, cash or other property receivable upon consummation of such transaction, subject to adjustment as provided in paragraph 4(e) above following the date of consummation of such transaction. As a condition to any such transaction, the Corporation or the person formed by the consolidation or resulting from the merger or which acquires such assets or which acquires the Corporation’s shares, as the case may be, shall make provisions in its certificate or articles of incorporation or other constituent document to (i) establish such right and (ii) ensure that any such transaction does not, in and of itself, effect the holders’ rights to the Liquidation Value. The certificate or articles of incorporation or other constituent document shall provide for adjustments which, for events subsequent to the effective date of the certificate or articles of incorporation or other constituent document, shall be as nearly equivalent as may be practicable to the adjustments consolidation, merger, sale, transfer or share exchange assuming that such holder of Common Stock provided for in this paragraph 4. The provisions of this paragraph 4(f) shall similarly apply to successive reclassifications, consolidations, mergers, sales, transfers or share exchanges.

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(g)          If:

(i)          the Corporation shall take any action which would require an adjustment in the Conversion Rate pursuant to paragraph 4(e); or

(ii)         the Corporation shall authorize the granting to the holders of its Common Stock generally of rights, warrants or options to subscribe for or purchase any shares of any class or any other rights, warrants or options; or

(iii)        there shall be any reclassification or change of the Common Stock (other than a subdivision or combination of its outstanding Common Stock or a change in par value) or any consolidation, merger or statutory share exchange to which the Corporation is a party and for which approval of any stockholders of the Corporation is required, or the sale or transfer of all or substantially all of the assets of the Corporation; or

(iv)       there shall be a voluntary or involuntary dissolution, liquidation or winding-up of the Corporation;

then, the Corporation shall cause to be delivered to each Holder, as promptly as possible, but at least 20 days prior to the applicable date hereinafter specified, a notice stating (A) the date on which a record is to be taken for the purpose of such dividend, distribution or granting of rights, warrants or options or, if a record is not to be taken, the date as of which the holders of Common Stock of record to be entitled to such dividend, distribution or rights, warrants or options are to be determined, or (B) the date on which such reclassification, change, consolidation, merger, statutory share exchange, sale, transfer, dissolution, liquidation or winding-up is expected to become effective or occur, and the date as of which it is expected that holders of Common Stock of record shall be entitled to exchange their shares of Common Stock for securities or other property deliverable upon such reclassification, change, consolidation, merger, statutory share exchange, sale, transfer, dissolution, liquidation or winding-up.  Failure to give such notice or any defect therein shall not affect the legality or validity of the proceedings described in this paragraph 4(g).

(h)        The Corporation shall promptly cause a notice of an adjusted Conversion Rate to be delivered to each Holder.

(i)          In any case in which paragraph 4(e) provides that an adjustment shall become effective immediately after a record date for an event and the date fixed for such adjustment pursuant to paragraph 4(e) occurs after such record date but before the occurrence of such event, the Corporation may defer until the actual occurrence of such event issuing to the holder of any Series B Preferred Shares converted after such record date and before the occurrence of such event the additional shares of Common Stock issuable upon such conversion by reason of the adjustment required by such event over and above the Common Stock issuable upon such conversion before giving effect to such adjustment.

(j)         Subject to paragraph 4(c) hereof, the Corporation shall at all times reserve and keep available for issuance upon the conversion of  the shares of  the Series B Preferred Stock the maximum number of each of its authorized but unissued shares of Common Stock as is reasonably anticipated to be sufficient to permit the conversion of all outstanding shares of the Series B Preferred Stock, and shall take all action required to increase the authorized number of shares of Common Stock, or any other actions necessary or desirable, if at any time  there shall be insufficient authorized but  unissued shares of Common Stock to permit such reservation or to permit the conversion of all outstanding shares of the Series B Preferred Stock.

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5.            Limitations on Conversion.  The Company shall not effect any conversion of the Series B Preferred Stock, and the Holder shall not have the right to convert any portion of the Series B Preferred Stock, pursuant to Section 4 or otherwise, to the extent that after giving effect to such issuance after conversion, the Holder (together with the Holder’s Affiliates, and any other Persons acting as a group together with the Holder or any of the Holder’s Affiliates (such Persons, “Attribution Parties”)), would beneficially own in excess of the Beneficial Ownership Limitation (as defined below).  For purposes of the foregoing sentence, the number of shares of Common Stock beneficially owned by the Holder and its Affiliates and Attribution Parties shall include the number of shares of Common Stock issuable upon conversion of the Series B Preferred Stock with respect to which such determination is being made, but shall exclude the number of shares of Common Stock which would be issuable upon (i) exercise of the remaining, nonexercised shares of Series B Preferred Stock beneficially owned by the Holder or any of its Affiliates or Attribution Parties and (ii) exercise or conversion of the unexercised or nonconverted portion of any other securities of the Company subject to a limitation on conversion or exercise analogous to the limitation contained herein beneficially owned by the Holder or any of its Affiliates or Attribution Parties.  Except as set forth in the preceding sentence, for purposes of this Section 5, beneficial ownership shall be calculated in accordance with Section 13(d) of the Exchange Act and the rules and regulations promulgated thereunder, it being acknowledged by the Holder that the Company is not representing to the Holder that such calculation is in compliance with Section 13(d) of the Exchange Act and the Holder is solely responsible for any schedules required to be filed in accordance therewith.   To the extent that the limitation contained in this Section 5 applies, the determination of whether the Series B Preferred Stock is convertible (in relation to other securities owned by the Holder together with any Affiliates and Attribution Parties) and of which portion of the Series B Preferred Stock is convertible shall be in the sole discretion of the Holder, and the submission of a Notice of Exercise shall be deemed to be the Holder’s determination of whether this Warrant is exercisable (in relation to other securities owned by the Holder together with any Affiliates and Attribution Parties) and of which portion of this Warrant is exercisable, in each case subject to the Beneficial Ownership Limitation, and the Company shall have no obligation to verify or confirm the accuracy of such determination.  In addition, a determination as to any group status as contemplated above shall be determined in accordance with Section 13(d) of the Exchange Act and the rules and regulations promulgated thereunder.  For purposes of this Section 5, in determining the number of outstanding shares of Common Stock, a Holder may rely on the number of outstanding shares of Common Stock as reflected in (A) the Company’s most recent periodic or annual report filed with the Commission, as the case may be, (B) a more recent public announcement by the Company or (C) a more recent written notice by the Company or its transfer agent setting forth the number of shares of Common Stock outstanding.  In any case, the number of outstanding shares of Common Stock shall be determined after giving effect to the conversion or exercise of securities of the Company, including the Series B Preferred Stock, by the Holder or its Affiliates or Attribution Parties since the date as of which such number of outstanding shares of Common Stock was reported.  The “Beneficial Ownership Limitation” shall be 4.99% of the number of shares of the Common Stock outstanding immediately after giving effect to the issuance of shares of Common Stock issuable upon conversion of the Series B Preferred Stock.  The Holder, upon notice to the Company, may increase or decrease the Beneficial Ownership Limitation provisions of this Section 5, provided that the Beneficial Ownership Limitation in no event exceeds 9.99%.  The provisions of this paragraph shall be construed and implemented in a manner otherwise than in strict conformity with the terms of this Section 5 to correct this paragraph (or any portion hereof) which may be defective or inconsistent with the intended Beneficial Ownership Limitation herein contained or to make changes or supplements necessary or desirable to properly give effect to such limitation.

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6.            Voting Rights.

(a)        Holders of the Series B Preferred Stock shall vote, on an “as converted” basis together with the Common Stock, as a single class on all matters to which shareholders of the Corporation are entitled to vote.

(b)        Whenever holders of the Series B Preferred Shares are required or permitted to take any action by vote, such action may be taken without a meeting on written consent, setting forth the action so taken and signed by the holders of the Series B Preferred Shares having not less than the minimum number of votes that would be necessary to authorize or take such action at a meeting at which all shares entitled to vote thereon were present and voted. 

(c)        Holders of the Series B Preferred Stock shall vote together as a separate class on all matters which impact the rights, value, or ranking of the Common Stock or Series B Preferred Stock, as provided herein.

(d)        So long as any shares of the Series B Preferred Shares are outstanding, the Corporation shall not without first obtaining the approval (by vote or written consent, as provided by law) of a majority of the then outstanding shares of the Series B Preferred Shares, voting as a separate class:

(i)          in any manner authorize, issue or create (by reclassification or otherwise) any new class or series of shares having rights, preferences or privileges equal or senior to or on parity the Series B Preferred Shares;

(ii)         adversely alter or change the rights, preferences, designations or privileges of the Series B Preferred Shares; or

(iii)        amend the Corporation’s Articles of Incorporation of By-laws in a manner that adversely affects the rights, preferences, designations or privileges of the holders of the Series B Preferred Shares;

(e)        Except as set forth in this Certificate of Designation, the Series B Preferred Shares shall have no other voting rights or other rights to consent to any matter to which stockholders of the Corporation may vote upon or consent to.

7.            Status of Shares. All Series B Preferred Shares that are at any time converted pursuant to paragraph 4 above, and all Series B Preferred Shares that are otherwise reacquired by the Corporation and subsequently canceled by the Board of Directors, shall be retired and shall not be subject to reissuance.

8.             Certain Definitions. As used in this Certificate, the following terms shall have the following respective meanings:

“Affiliate” of any specified person means any other person directly or indirectly controlling or controlled by or under common control with such specified person. For purposes of this definition, “control” when used with respect to any person means the power to direct the management and policies of such person, directly or indirectly, whether through the ownership of voting securities or otherwise; and the term “controlling” and “controlled” having meanings correlative to the foregoing.

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“Capital Stock” of any person or entity means any and all shares, interests, rights to purchase, warrants, options, participations or other equivalents of or interests in the common stock or preferred stock of such person or entity, including, without limitation, partnership and membership interests.

“Change of Control” means the existence or occurrence of any of the following: (a) the sale, conveyance or disposition of all or substantially all of the assets of the Corporation; (b) the effectuation of a transaction or series of related transactions in which more than fifty percent (50%) of the voting power of the Corporation is disposed of (other than as a direct result of normal, uncoordinated trading activities in the Common Stock generally); (c) the consolidation, merger or other business combination of the Corporation with or into any other entity, immediately following which the prior stockholders of the Corporation fail to own, directly or indirectly, at least fifty percent (50%) of the voting equity of the surviving entity; (d) a transaction or series of transactions in which any person or “group” (as such term is used in Sections 13(d) and 14(d) of the Exchange Act) acquires more than fifty percent (50%) of the voting equity of the Corporation; (e) the replacement of a majority of the Board of Directors with individuals who were not nominated or elected by at least a majority of the directors at the time of such replacement; or (f) a transaction or series of transactions that constitutes or results in a “going private transaction” (as defined in Section 13(e) of the Exchange Act and the regulations of the Commission issued thereunder).

“Holder” means any holder of Series B Preferred Shares, all of such holders being the “Holders.”

“Stated Value” of any share of Series B Preferred Stock shall mean $1.00.

IN WITNESS WHEREOF, the Corporation has caused this Certificate to be duly executed on its behalf by its undersigned Chief Executive Officer as of February __, 2017.

	 	
By:

	
_____________________

	 	 	
Name: [___________________]

	 	 	
Title:  Chief Executive Officer

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ANNEX I

CONVERSION NOTICE

The undersigned hereby elects to convert shares of Series B Preferred Stock (the “Preferred Stock”), represented by stock certificate No(s).                       , into shares of common stock (“Common Stock”) of [___________________] (the “Corporation”) according to the terms and conditions of the Certificate of Designation relating to the Preferred Stock (the “Certificate of Designation”), as of the date written below. Capitalized terms used herein and not otherwise defined shall have the respective meanings set forth in the Certificate of Designation.

Conversion Date:

Number of Shares of Series B Preferred Stock to be Converted:

 

Applicable Conversion Rate:

 

Number of Shares of Common Stock to be Issued: Name of Holder:

 

Address:

 

	
Signature:

	 	 
	
Name:

	 	 
	
Title:

	 	 

  

 

 

8EX-10.1

 Exhibit 10.1 

AMENDMENT OF LEASE 
 THIS
AMENDMENT OF LEASE (hereinafter “Amendment”) is entered into as of the 27th day of March 2017, by BHX, LLC, a Massachusetts limited liability company, as Trustee of 784 Realty Trust (hereinafter “Landlord”),
and INFINITY PHARMACEUTICALS, INC., a Delaware corporation (hereinafter “Tenant”). 
 WITNESSETH 

WHEREAS, Landlord and Tenant are parties to a Lease dated September 25, 2014 (the “Lease”), pursuant to which Landlord
has leased to Tenant space in the building located at and commonly known as 784 Memorial Drive, Cambridge Massachusetts. All capitalized terms used in this Amendment which are defined in the Lease and not otherwise defined in this Amendment have the
meanings given in the Lease; and 
 WHEREAS, the Lease Term will expire on March 31, 2025. Tenant desires to terminate the Lease prior
to the expiration of the Lease Term and, for the consideration stated herein, Landlord is willing to accommodate Tenant’s desire for early termination on the terms set forth herein. 

Statement of Amendment 

NOW, THEREFORE, in consideration of the undertakings of the parties as set forth below and other good and valuable consideration, the receipt
and sufficiency of which consideration is hereby acknowledged by both Landlord and Tenant, Landlord and Tenant hereby agree as follows: 

1. Within five (5) Business Days after the Termination Contingencies Date: 

(a) If the Landlord’s Termination Contingencies (defined below) have been satisfied on or before the Termination Contingencies Date or
Landlord, in its sole discretion, elects to waive the Landlord’s Termination Contingencies, Landlord shall send to Tenant a written notice (the “Landlord’s Termination Notice”) notifying Tenant that the Landlord’s
Termination Contingencies have been satisfied or waived by Landlord; and 
 (b) If the Tenant’s Termination Contingency (defined below)
has been satisfied on or before the Termination Contingencies Date or Tenant, in its sole discretion, elects to waive the Tenant’s Termination Contingency, then, in either such event Tenant shall send to Landlord a written notice (the
“Tenant’s Termination Notice” and, together with the Landlord’s Termination Notice, the “Termination Notices”) notifying Landlord that Tenant’s Termination Contingency has been satisfied or waived by
Tenant. 
 2. 
 (a) If
(i) the Landlord’s Termination Notice is timely given in accordance with clause (a) of Section 1 above and (ii) either (A) the Tenant’s Termination Notice is timely given in accordance with clause (b) of
Section 1 above or (ii) Tenant is given, on or before the Termination Contingencies Date, a copy of a consent (a “Qualifying Lender Consent”) executed by Landlord’s lender (the “Lender”) and addressed
to Tenant (or to Landlord and Tenant) consenting to the termination of the Lease and/or agreeing to be bound by this Amendment, without any conditions or conditioned solely on Tenant’s performance of its obligations under this Amendment (which
consent may, but need not, be the same as the consent referenced in Section 3(1)(a)(i) below), then the Lease shall terminate as of June 30, 2017 (the “Early Termination Date”), subject to the payment of the Early Termination
Consideration (defined below) by Tenant to Landlord. 
 (b) If (i) the Landlord’s Termination Notice is not timely given in
accordance with clause (a) of Section 1 above or (ii) the Tenant’s Termination Notice is not timely given in accordance with 

 
clause (b) of Section 1 above and the Tenant has not timely received a Qualifying Lender Consent, then the Termination Contingencies shall be deemed to have not been satisfied by the
Termination Contingencies Date, this Amendment shall be null and void ab initio and the Lease shall remain in effect in accordance with the terms thereof as they existed immediately prior to execution and delivery of this Amendment.

 3. As a condition precedent to the effectiveness of this Amendment, the following contingencies shall have been satisfied on or before
May 1, 2017 (the “Termination Contingencies Date”): (a) (i) Lender shall have consented in writing (addressed to Landlord alone or to Landlord and Tenant) to this Amendment and to the termination of the Lease in
accordance with the terms and conditions of this Amendment, on terms and conditions acceptable to Landlord in its sole and absolute discretion, and (ii) Landlord shall have entered into a new lease or leases with respect to 100% of the Premises
on terms and conditions satisfactory to Landlord, in its sole and absolute discretion (collectively, the “Landlord’s Termination Contingencies”) and (b) Tenant shall have received a Qualifying Lender Consent (the
“Tenant’s Termination Contingency” and, together with the Landlord’s Termination Contingencies, the “Termination Contingencies”). 

4. In consideration for the early termination of the Lease pursuant to the terms of this Amendment, Tenant shall pay to Landlord $5,000,000.00
(the “Early Termination Consideration”), of which (a) $4,500,000.00 (the “First Installment”) shall be paid by Tenant by wire transfer of federal funds to be received by Landlord on or before the date that is no
more than the later of five (5) calendar days after (i) the date on which Landlord gives Tenant a Landlord’s Termination Notice and (ii) the earlier of (A) the date on which Tenant gives Landlord a Tenant’s Termination
Notice and (B) the date of satisfaction of the Tenant’s Termination Contingency and (b) $500,000.00 (the “Second Installment”) shall be paid by Tenant by wire transfer of federal funds to be received by Landlord on or
before the Early Termination Date. In the event that Tenant fails to: 
 (1) Pay the First Installment on or before the date when due, such
failure shall constitute an Event of Default under the Lease entitling the Landlord to exercise all of its rights and remedies under the Lease (including, but not limited to, drawing upon the Letter of Credit held as the Security Deposit under the
Lease) and, in addition, Landlord may, at its option, elect to either (x) terminate this Amendment and reinstate the terms of the Lease as they existed prior to execution of this Amendment, with such Event of Default to survive such
reinstatement of the Lease and termination of this Amendment or (y) enforce the terms and conditions of this Amendment as written, with such failure constituting an Event of Default under the Lease; or 

(2) Pay the Second Installment on or before the date when due, such failure shall constitute an Event of Default under the Lease entitling the
Landlord to exercise all of its rights and remedies under the Lease (including, but not limited to, drawing upon the Letter of Credit held as the Security Deposit under the Lease) for the amount of the Second Installment; provided, however, that the
maximum liability of Tenant for a failure to pay the Second Installment shall be limited to, the sum of (x) the amount of the Second Installment, plus (y) Interest Payments and Administrative Expenses at the rates and in the amounts
provided in Section 12.9 of the Lease with respect to Additional Rent, plus (z) expenses of enforcement as provided in Section 12.6 of the Lease. 

Landlord shall return the Letter of Credit to Tenant within three (3) Business Days after Landlord’s receipt of all amounts due under this
Section 4. 
 5. If, and only if, (x) the Lease terminates pursuant to this Amendment, effective as of the Early Termination Date,
and (y) Tenant timely pays the Early Termination Consideration, then Landlord releases Tenant from any and all liabilities and obligations under, arising from or in any way connected with the Lease, other than liabilities and obligations
(a) accruing under the Lease through the Early Termination Date, including, but not limited to the obligation to pay any and all Base Rent, Additional Rent and Parking Rent (as defined in the Declaration), and/or (b) that are specified in
the Lease (as affected by this Amendment) to survive the expiration or earlier termination of the Lease. If, and only if, the Lease 

  
 -2- 

 
terminates pursuant to this Amendment, effective as of the Early Termination Date, Tenant releases Landlord from any and all liabilities and obligations under, arising from or in any way
connected with the Lease, other than liabilities and obligations (i) accruing under the Lease through the Early Termination Date, and/or (ii) that are specified in the Lease to survive the expiration or earlier termination of the Lease (as
affected by this Amendment). 
 6. If the Lease terminates pursuant to this Amendment, Tenant shall surrender the Premises to Landlord on or
before the Early Termination Date subject to the following terms and conditions: (a) the Premises shall be free and clear of Tenant and/or any subtenants, assignees or other occupants; (b) Tenant shall remove all Hazardous Materials as a
result of the activities of Tenant or any of Tenant’s Invitees from the Project in accordance with Section 5.3 of the Lease and all Environmental Laws and (c) the Premises shall be broom clean (but without any obligation to remove
personal property) and otherwise in substantially the same repair and condition as they are on the date of this Amendment (reasonable wear and tear excepted). Landlord shall have the right to occupy, and to grant to others the right to occupy, the
Premises from and after the Early Termination Date. In connection with Tenant’s surrender of the Premises to Landlord, except as provided above in this Section 6, (i) Tenant shall have no obligation to remove any personal property, goods
or effects belonging to Tenant or anyone claiming through or under Tenant, and (ii) the Alterations (if any), Outside Equipment (if any), Base Building Work and the TI Work shall be the property of Landlord and shall remain upon, and be
surrendered with, the Premises. If Tenant fails to deliver the Premises to Landlord on or before the Early Termination Date in the condition required by this Amendment, the provisions under Section 13.9 of the Lease shall apply. 

7. At any time after the satisfaction or waiver of the Termination Contingencies, Landlord may terminate the designation of Tenant as a Parcel
A Parking Tenant (as defined in the Declaration) and/or reduce the number of Rented Parking Spaces (as defined in the Declaration) by such number of Rented Parking Spaces as determined by Landlord (such reduction to be effective on or after
July 1, 2017), by giving written notice of such change to Parcel B Owner pursuant to Section 4.6.2 of the Declaration, and Tenant agrees to execute any documents requested by Landlord in connection therewith. 

8. In the event that the Lease is terminated pursuant to this Amendment, Tenant agrees to execute and deliver a Termination of Notice of Lease
and such other documents as may be reasonably requested by Landlord for recording in any registry of deeds or land court to evidence the termination of the Lease. 

9. The parties agree not to disclose the terms of this Amendment except to their affiliates, and their respective officers, directors,
employees, agents, managers, shareholders, members, partners, lenders, attorneys, accountants, financial advisors, lenders, investors, or upon an order of a court of competent jurisdiction after prior notice to both parties and further provided that
the terms of this Amendment may be disclosed by Tenant to the representatives of any existing subtenant and for financial reporting and credit related activities. Landlord acknowledges that Tenant, as a public company, may be required to make
certain disclosures about this Amendment, including filing the Amendment as an amendment to a material contract, and that such disclosures will not violate this Section 9. 

10. In the event that the Lease is terminated effective as of the Early Termination Date, upon Landlord’s receipt of 100% of the Early
Termination Consideration, Landlord shall pay CB Richard Ellis/New England a professional accommodation fee in the amount of $200,000.00 in connection with the negotiation and execution of this Amendment. Except as set forth in the immediately
preceding sentence, each party represents that it has not dealt with any Person in connection with the Premises or the negotiation or execution of this Amendment other than officers, employees and attorneys of Landlord, Tenant and Brokers. Each
party shall indemnify and save harmless the other from and against all claims, liabilities, costs and expenses incurred as a result of any breach of the foregoing representation. The fees payable to Brokers for this Amendment, if any, shall be
payable by Landlord. 
 11. This Amendment constitutes the entire agreement between the parties hereto regarding the early termination of
the Lease and supersedes all prior negotiations regarding the subject matter 

  
 -3- 

 
hereof. This Amendment will be governed by and construed in accordance with the laws of the Commonwealth of Massachusetts. Any notices given hereunder shall be given in accordance with the notice
provisions in the Lease. 
 12. To the extent that the provisions of this Amendment are inconsistent with the provisions of the Lease, the
provisions of this Amendment will control and the Lease will be deemed to be amended hereby. Except as amended by this Amendment, the provisions of the Lease remain in full force and effect. 

13. This Amendment may be executed in multiple counterparts, each of which will be an original, but all of which, taken together, will
constitute one and the same Amendment. This Amendment may be signed by facsimile signatures or other electronic delivery of an image file reflecting the execution hereof, and if so signed, may be relied on by all parties as if the document were a
manually signed original and will be binding on the undersigned for all purposes.
 [Remainder of page intentionally blank; signature page
follows.] 

  
 -4- 

 IN WITNESS WHEREOF, Landlord and Tenant have executed this Amendment as of the date first set
forth above. 
  

			
	BHX, LLC, as Trustee of 784 Realty Trust
		
	By:	 	 /s/ Robert Schlager

	Name:	 	 Robert Schlager

	Title:	 	 Member

	
	INFINITY PHARMACEUTICALS, INC.
		
	By:	 	 /s/ Lawrence Bloch

	Name:	 	 Lawrence Bloch, M.D., J.D.

	Title:	 	 President

  
 -5-

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