Document:

EX-4.4.2

 Exhibit 4.4.2 

Schedule of Holders of 
 Warrants
to Purchase Common Stock 
  

																	
	 Holder
	  	Number of
Shares	 	  	Exercise
Price	 	  	Issuance
Date	 	  	Expiration
Date	 
	 Sol Barer
	  	 	121,227	 	  	$	1.75	 	  	 	5/16/2014	 	  	 	5/16/2019	 
	 InterWest Partners VIII, LP
	  	 	23,632	 	  	$	1.75	 	  	 	5/16/2014	 	  	 	5/16/2019	 
	 InterWest Partners IX, LP
	  	 	18,357	 	  	$	1.75	 	  	 	5/16/2014	 	  	 	5/16/2019	 
	 InterWest Investors Q VIII, LP
	  	 	680	 	  	$	1.75	 	  	 	5/16/2014	 	  	 	5/16/2019	 
	 InterWest Investors VIII, LP
	  	 	189	 	  	$	1.75	 	  	 	5/16/2014	 	  	 	5/16/2019	 
	 CMEA Ventures VII, L.P.
	  	 	10,446	 	  	$	1.75	 	  	 	5/16/2014	 	  	 	5/16/2019	 
	 CMEA Ventures VII (Parallel), L.P.
	  	 	268	 	  	$	1.75	 	  	 	5/16/2014	 	  	 	5/16/2019	 
	 Maxim Partners, LLC
	  	 	612,255	 	  	$	1.75	 	  	 	5/16/2014	 	  	 	5/16/2019	 

 THE WARRANT REPRESENTED HEREBY AND THE COMMON STOCK HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF
1933, AS AMENDED (THE “SECURITIES ACT”), OR ANY STATE SECURITIES LAWS AND NEITHER THIS WARRANT NOR THE COMMON STOCK NOR ANY INTEREST THEREIN MAY BE TRANSFERRED IN THE ABSENCE OF SUCH REGISTRATION OR AN EXEMPTION THEREFROM UNDER SUCH
SECURITIES ACT AND SUCH LAWS AND THE RULES AND REGULATIONS THEREUNDER. THE COMMON STOCK ISSUABLE UPON THE EXERCISE OF THIS WARRANT IS SUBJECT TO THE PROVISIONS OF A STOCKHOLDERS AGREEMENT, DATED AS OF THE DATE HEREOF, AS MAY BE AMENDED FROM TIME TO
TIME (A COPY OF WHICH ARE ON FILE WITH THE SECRETARY OF THE COMPANY), AND MAY NOT BE SOLD, TRANSFERRED, ASSIGNED, PLEDGED, HYPOTHECATED OR OTHERWISE DISPOSED OF EXCEPT IN COMPLIANCE WITH THE PROVISIONS OF SUCH STOCKHOLDERS AGREEMENT. 

Warrant Certificate No. C-_ 

Dated:                      

COMMON STOCK WARRANT 

CENTREXION CORPORATION 

THIS IS TO CERTIFY THAT for value received,
                         (the “Holder”) is entitled, subject to the terms and conditions set forth below, to purchase
from Centrexion Corporation, a Delaware corporation (the “Company”),                     
(        ) shares (the “Warrant Shares”) of Common Stock, par value $0.001 per share, of the Company (“Common Stock”), at a price per share equal to $1.75 (the “Exercise Price”).
This warrant (this “Warrant”) is being issued in connection with [the Placement Agency Agreement, dated October 14, 2013 (the “Placement Agency”), by and between
            and the Company. This Warrant is being issued in exchange for and replaces the Series B Convertible Preferred Stock Warrant (Certificate No.
        ),]1 [that certain Convertible Promissory Note, dated as of October 7, 2013, issued by Parent in favor of
                    , having an aggregate principal amount of $             (the
“Bridge Note”). This Warrant is being issued in exchange for and replaces the Series B Convertible Preferred Stock Warrant (Certificate No.
        )]2, dated November 20, 2013 (the “Original Issuance Date”), issued by the Company to the Holder to purchase
             shares of Series B Preferred Stock (the “Original Warrant”), after which the Original Warrant will be cancelled and be of no further force and effect. All Warrant
Shares issued under this Warrant pursuant to the Bridge Note are referred to herein, collectively, as the “Warrants.” 
 1.
Manner of Exercise; Expiration Date. 
 (a) This Warrant shall be exercisable in accordance with this Section 1
and Section 2 below from and after the date hereof until 5:00 p.m., New York time on the fifth (5th) anniversary of the Original Issuance Date (the “Exercise Period”). The Holder may from time to time during the Exercise Period on any
business day exercise this Warrant, for all or any part of the Warrant Shares purchasable at such time hereunder, by delivering to the Company at its principal office (i) a written notice of the Holder’s election to exercise this Warrant
(an “Exercise Notice”), which Exercise Notice shall be irrevocable and shall specify the number of Warrant Shares to be purchased, (ii) payment of the aggregate Exercise Price for the applicable number of Warrant Shares to be
purchased by check or wire transfer of immediately available funds to an account then specified by the Company and (iii) this Warrant (the date on which the foregoing items are delivered to the Company being hereinafter referred to as the
“Exercise Date”). Such Exercise Notice shall be in the form of Annex A hereto, duly executed by the Holder or its duly authorized agent. 

 

	1 	 This language applies only to the warrant issued to Maxim Partners, LLC. 

	2 	 This language is omitted in the warrant issued to Maxim Partners, LLC. 

 (b) Upon receipt of the items specified in Section 1(a), the Company
shall execute (or cause to be executed) and deliver (or cause to be delivered) to the Holder a certificate or certificates representing the aggregate number of full Warrant Shares issuable upon such exercise. This Warrant shall be deemed to have
been exercised and such certificate or certificates shall be deemed to have been issued, and the Holder shall be deemed to have become a Holder of record of such shares for all purposes, as of the Exercise Date. 

(c) If this Warrant is exercised in part, the Company shall, at the time of delivery of the certificate or certificates
representing the Warrant Shares being issued, deliver to the Holder a new Warrant evidencing the rights of the Holder to purchase the unpurchased Warrant Shares called for by this Warrant. Such new Warrant shall in all other respects be identical to
this Warrant. 
 (d) The Company shall pay any and all issue and other taxes (other than income taxes) that may be payable in
respect of the issuance of this Warrant or any issuance or delivery of Warrant Shares on exercise of this Warrant; provided, however, that the Company shall not be obligated to pay any transfer taxes resulting from any transfer requested by the
Holder of record of this Warrant in connection with any such exercise. 
 (e) The Company shall at all times reserve and keep
available out of its authorized but unissued shares of capital stock, solely for the purpose of effecting the exercise of this Warrant, such number of its shares of capital stock as shall from time to time be sufficient to effect such exercise of
this Warrant for the maximum number of shares of such class or series of capital stock issuable upon exercise of this Warrant; and if at any time the number of authorized but unissued shares of such capital stock shall not be sufficient to effect
such exercise of this Warrant for the maximum number of shares of such capital stock then issuable upon exercise hereunder, the Company will take such corporate action as may, in the opinion of its counsel, be necessary to increase its authorized
but unissued shares of such capital stock to such number of shares as shall be sufficient for such purpose, including, without limitation, engaging in best efforts to obtain the requisite stockholder approval of any necessary amendment to the
Company’s Certificate of Incorporation (as amended from time to time). The Company will not at any time close its stock transfer books in a manner which prevents the timely exercise of this Warrant. 

(f) If the Holder has not exercised this Warrant prior to the closing of a Corporate Transaction (as defined below) or in
connection with a Corporation Transaction as provided in Section 12, this Warrant shall automatically be deemed to be exercised in full in the manner set forth in Section 2, without any further action on behalf of the Holder, immediately
prior to such closing. In such case, if the fair market value of one share of Common Stock is less than the Exercise Price (at the date of calculation as set forth in Section 2), this Warrant will be deemed to be terminated without any further
payment. “Corporate Transaction” shall mean (A) the closing of the sale, transfer or other disposition of all or substantially all of the Company’s assets, (B) the consummation of the merger or consolidation of the
Company with or into another entity (except a merger or consolidation in which the holders of capital stock of the Company immediately prior to such merger or consolidation continue to hold at least 50% of the voting power of the capital stock of
the Company or the surviving or acquiring entity), (C) the closing of the transfer (whether by merger, consolidation or otherwise), in one transaction or a series of related transactions, to a person or group of affiliated persons (other than an
underwriter of this corporation’s securities), of the Company’s securities if, after such closing, such person or group of 

  
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affiliated persons would hold 50% or more of the outstanding voting stock of this corporation (or the surviving or acquiring entity), (D) an Initial Public Offering (as defined below) of the
Company or (E) a liquidation, dissolution or winding up of this corporation; provided, however, that a transaction shall not constitute a Corporate Transaction if its sole purpose is to change the state of the Company’s incorporation or to
create a holding company that will be owned in substantially the same proportions by the persons who held the Company’s securities immediately prior to such transaction. Notwithstanding the prior sentence, the sale of shares of the
Company’s preferred stock in a bona fide financing transaction shall not be deemed a “Corporate Transaction. 
 2. Net Exercise
Issue. Notwithstanding any provision herein to the contrary, if the fair market value of one share of Common Stock is greater than the Exercise Price (at the date of calculation as set forth below), in lieu of exercising this Warrant for cash,
the Holder may elect to receive shares equal to the value (as determined below) of this Warrant (or the portion thereof being canceled) by surrender of this Warrant at the principal office of the Company together with the properly endorsed Exercise
Notice in which event the Company shall issue to the Holder a number of shares of Common Stock computed using the following formula: 
 X =
Y (A-B) 
 A 

Where X =   the number of Warrant Shares to be issued to the Holder 

Y =   the number of Warrant Shares with respect to which this Warrant is being exercised 

A =   the fair market value of one share of Common Stock (at the date of such calculation) 

B =   Exercise Price (as adjusted to the date of such calculation) 

For purposes of the above calculation, (a) if the Company has consummated a sale of shares of its equity securities in a bona fide firm
commitment underwritten public offering pursuant to a registration statement on Form S-1 (or a successor form) under the Securities Act (an “Initial Public Offering”), then the fair market value of
one share of Common Stock shall be valued at the volume weighted average price of the Common Stock for the 30 trading days immediately prior to the Exercise Date, as reported by Bloomberg; or (b) if the Company has not consummated an Initial Public
Offering, then the fair market value shall be determined in good faith by the Board of Directors of the Company. 
 3. Adjustment of
Exercise Price and Number of Conversion Shares. 
 (a) Adjustments for Stock Dividends, Splits, etc. If the
Company declares or pays a dividend on the outstanding shares of the Common Stock or other securities, then upon exercise of this Warrant, for each Warrant Share acquired, Holder shall receive, without cost to Holder, the total number and kind of
securities to which Holder would have been entitled had Holder owned the Warrant Shares of record as of the date the dividend occurred. If the Company subdivides the outstanding shares of Common Stock by reclassification or otherwise into a greater
number of shares, the number of Warrant Shares purchasable hereunder shall be proportionately increased and the Warrant Price shall be proportionately decreased. If the outstanding shares of Common Stock are combined or consolidated, by
reclassification or otherwise, into a lesser number of shares, the Warrant Price shall be proportionately increased and the number of Warrant Shares shall be proportionately decreased. 

  
 3 

 (b) Reclassification, Reorganization and Consolidation. In case of
any reclassification, capital reorganization or change in the capital stock of the Company, then, as a condition of such reclassification, reorganization or change, lawful provision shall be made, and duly executed documents evidencing the same from
the Company or its successor shall be delivered to the Holder, so that the Holder shall have the right at any time prior to the expiration of this Warrant to purchase, at a total price equal to that payable upon the exercise of this Warrant, the
kind and amount of shares of stock and other securities or property receivable in connection with such reclassification, reorganization or change by a holder of the same number and type of securities as were purchasable as Warrant Shares by the
Holder immediately prior to such reclassification, reorganization or change. In any such case appropriate provisions shall be made with respect to the rights and interest of the Holder so that the provisions hereof shall thereafter be applicable
with respect to any shares of stock or other securities or property deliverable upon exercise hereof, and appropriate adjustments shall be made to the Exercise Price per Warrant Share payable hereunder, provided the aggregate Exercise Price shall
remain the same. 
 4. Fractional Shares. No fractional Warrant Shares shall be issuable upon exercise or conversion of the Warrant
and the number of Warrant Shares to be issued shall be rounded up to the nearest whole Warrant Share. 
 5. Replacement of Warrant. On
receipt of evidence reasonably satisfactory to the Company of the loss, theft, destruction or mutilation of this Warrant and, in the case of any such loss, theft or destruction of this Warrant, on delivery of an indemnity agreement reasonably
satisfactory in form and amount to the Company or, in the case of any such mutilation, on surrender and cancellation of this Warrant, the Company at its expense will execute and deliver, in lieu thereof, a new Warrant of like tenor. 

6. Negotiability, etc. This Warrant is issued upon the following terms, all of which the Holder hereof by the taking hereof consents and
agrees: 
 (a) The Holder shall not be entitled to pledge, mortgage, transfer, endorse or otherwise convey this Warrant (a
“Transfer”), in whole or in part, without with the prior written consent of the Company, other than to Affiliates (as defined below). To the extent permitted by the preceding sentence, the Holder and its direct and indirect transferees may
Transfer all or any portion of this Warrant by surrendering this Warrant to the Company together with a completed assignment in the form attached hereto as Annex B. Upon such surrender, the Company shall deliver a new Warrant or Warrants to
the person or persons entitled thereto and, if applicable, shall deliver to Holder a new Warrant evidencing the right of Holder to purchase the balance of the Warrant Shares subject to purchase hereunder. The term “Holder” as used herein
shall include any transferee to whom this Warrant has been Transferred in accordance with this Section 6. The term “Affiliate” as used herein means, with respect to any Holder, any other person or entity who, directly or indirectly,
controls, is controlled by, or is under common control with such Holder, including without limitation any general partner, managing member, limited partner, officer or director of such Holder or any venture capital fund now or hereafter existing
that is controlled by one or more general partners or managing members of, or shares the same management company with, such Holder. 

  
 4 

 (b) The Holder shall not be entitled to vote or to receive dividends or to
be deemed the Holder of capital stock that may at any time be issuable upon exercise of this Warrant for any purpose whatsoever, nor shall anything contained herein be construed to confer upon the Holder any of the rights of a stockholder of the
Company or any right to vote for the election of directors or upon any matter submitted to stockholders at any meeting thereof, or to give or withhold consent to any corporate action (whether upon any recapitalization, issuance or reclassification
of stock, change of par value or change of stock to no par value, consolidation, merger or conveyance or otherwise), or to receive notice of meetings, or to receive dividends or subscription rights, until the Holder shall have exercised this Warrant
and been issued shares of capital stock in accordance with the provisions hereof. 
 (c) Neither this Warrant nor any shares
of capital stock or other securities purchased pursuant to this Warrant have been registered under the Securities Act and applicable state securities laws. Therefore, the transfer or exchange of this Warrant or such shares may be made only in a
transaction permitted under the Securities Act and applicable state securities laws or pursuant to an exemption therefrom. Prior to registration, the certificates evidencing the Warrant Shares or other securities issued on the exercise of this
Warrant shall bear a legend to the effect that the shares evidenced by such certificates have not been registered under the Securities Act and applicable state securities laws. 

(d) Until this Warrant is transferred on the books of the Company, the Company may treat the registered Holder hereof as the
absolute owner hereof for all purposes, notwithstanding any notice to the contrary. 
 7. Notices, etc. All notices and other
communications from the Company to the Holder of this Warrant shall be sent by electronic transmission or overnight courier or shall be mailed by first class registered or certified mail, postage prepaid, at such address as may have been furnished
to the Company in writing by such Holder or, until any such Holder furnishes to the Company an address, then to, and at the address of, the last Holder of this Warrant who has so furnished an address to the Company. All such notices and
communications shall, when mailed, be effective when deposited in the mails and, when sent by electronic transmission or overnight courier, delivered, be effective when received. 

8. Amendments. This Warrant and any term hereof may be changed, waived, discharged or terminated only by an instrument in writing signed
by the party against which enforcement of such change, waiver, discharge or termination is sought. 
 9. Governing Law. This Warrant
shall be construed and enforced in accordance with and governed by the laws of the State of Delaware without regard to the laws that might be applied under any conflict of laws principles. 

10. Headings. The headings in this Warrant are for purposes of reference only, and shall not limit or otherwise affect any of the terms
hereof. 
 11. Severability. The invalidity or unenforceability of any provision hereof shall in no way affect the validity or
enforceability of any other provision. 
 12. Assumption of Warrant. Subject to Section 1(f), if at any time while this Warrant,
or any portion thereof, is outstanding and unexpired there shall be a Corporate Transaction, then, as a part of such transaction, the Company shall provide notice to the Holder prior to the closing of such Corporate Transaction and lawful provision
shall be made so that the Holder shall be entitled to receive upon exercise of this Warrant, during the period specified herein and upon payment of the Exercise Price then in effect, the 

  
 5 

 number of shares of stock or other securities or property of the successor corporation resulting from the
Corporate Transaction which a holder of the shares deliverable upon exercise of this Warrant would have been entitled to receive in such Corporate Transaction if this Warrant had been exercised immediately before such Corporate Transaction, all
subject to adjustment as provided in Section 3. If the Holder does not exercise this Warrant pursuant to this Section 12 prior to the closing of a Corporate Transaction, then Section 1(f) shall apply. 

[END OF TEXT. SIGNATURE PAGE FOLLOWS.] 

  
 6 

 IN WITNESS WHEREOF, the Company has caused this Warrant to be executed by a duly authorized
officer as of the date first written above. 
  

			
	CENTREXION CORPORATION
		
	By:	 	
                     

	Name:	 	
	Title:	 	

  

			
	ACCEPTED AND AGREED:
		
	By:	 	
                     

	Name:	 	
	Title:	 	

  
 [Signature Page to
Common Stock Warrant] 

 Annex A 

Form of Exercise Notice 
 (To be executed if
Holder desires to exercise the Warrants evidenced by this Warrant Certificate). 
 TO CENTREXION CORPORATION 

 

	 	❑	 The undersigned hereby (1) irrevocably elects to exercise
                    Warrant Shares represented by this Warrant to purchase
                    shares of Common Stock issuable upon the exercise of such Warrant, (2) makes payment in full of the aggregate Exercise Price
for such Warrants by enclosure of a certified or bank cashier’s check therefor, upon condition that a new Warrant be issued for the balance of the Warrant Shares remaining, if any, and (3) requests that a certificate for the shares of
Common Stock purchased hereunder be issued in the name of and delivered to: 

 (Please print name and address) 

 

	 	❑	 The undersigned hereby elects to convert
                                        percent
(        %) of the value of the Warrant pursuant to the provisions of Section 2 of the Warrant. 

If such number of Warrant Shares not be all of the Warrant Shares evidenced by this Warrant Certificate, a new Warrant for the balance remaining of such
Warrant Shares shall be registered in the name of and delivered to: 
 (Please print name and address) 

 

			
	Dated: 	 	  

		
	Signature:	 	  

  
 8 

 Annex B 

Form of Assignment 
 (To be executed by the
registered Holder if such Holder desires to transfer the attached Warrant.) 
 FOR VALUE RECEIVED,
                                        
hereby sells, assigns, and transfers unto
                                        a
Warrant to purchase     shares of Common Stock, par value $0.001 per share, of Centrexion Corporation, a Delaware corporation (the “Company”), together with all right, title, and interest therein, and does
hereby irrevocably constitute and appoint                     attorney to transfer such Warrant on the books of the Company, with full power
of substitution. 
 The undersigned represents, unless the sale of this Warrant has been registered under the Securities Act of 1933, as
amended (the “Securities Act”), that the undersigned is acquiring such Warrant for its own account for investment and not with a view to or for sale in connection with any distribution thereof (except for any resale pursuant to a
Registration Statement under the Securities Act). 
  

			
	Dated: 	 	
                     

		
	Signature:	 	
                     

  
 9EX-4.4.3

 Exhibit 4.4.3 

Schedule of Holders of 
 Warrants to
Purchase Common Stock 
  

																					
	 Holder
	  	Number
of Shares	 	  	Exercise
Price	 	  	Issuance
Date	 	  	Expiration
Date	 	  	Preamble
Original
Issuance
Date	 
	 CIFCO International Group
	  	 	210,000	 	  	$	1.75	 	  	 	6/2/2014	 	  	 	6/2/2019	 	  	 	11/20/2013	 
	 Tianning (Tina) Yu
	  	 	90,000	 	  	$	1.75	 	  	 	6/2/2014	 	  	 	6/2/2019	 	  	 	6/1/2014	 

 THE WARRANT REPRESENTED HEREBY AND THE COMMON STOCK HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF
1933, AS AMENDED (THE “SECURITIES ACT”), OR ANY STATE SECURITIES LAWS AND NEITHER THIS WARRANT NOR THE COMMON STOCK NOR ANY INTEREST THEREIN MAY BE TRANSFERRED IN THE ABSENCE OF SUCH REGISTRATION OR AN EXEMPTION THEREFROM UNDER SUCH
SECURITIES ACT AND SUCH LAWS AND THE RULES AND REGULATIONS THEREUNDER. THE COMMON STOCK ISSUABLE UPON THE EXERCISE OF THIS WARRANT IS SUBJECT TO THE PROVISIONS OF A STOCKHOLDERS AGREEMENT, DATED AS OF NOVEMBER 20, 2013, AS MAY BE AMENDED FROM
TIME TO TIME (A COPY OF WHICH ARE ON FILE WITH THE SECRETARY OF THE COMPANY), AND MAY NOT BE SOLD, TRANSFERRED, ASSIGNED, PLEDGED, HYPOTHECATED OR OTHERWISE DISPOSED OF EXCEPT IN COMPLIANCE WITH THE PROVISIONS OF SUCH STOCKHOLDERS AGREEMENT. 

Warrant Certificate No. C-_ 

Dated:
                             

COMMON STOCK WARRANT 

CENTREXION CORPORATION 

THIS IS TO CERTIFY THAT for value received,
                                 (the “Holder”) is entitled, subject to the
terms and conditions set forth below, to purchase from Centrexion Corporation, a Delaware corporation (the “Company”),
                             (            )
shares (the “Warrant Shares”) of Common Stock, par value $0.001 per share, of the Company (“Common Stock”), at a price per share equal to $1.75 (the “Exercise Price”). This warrant (this “Warrant”) is being
issued in connection with that certain Consulting and Independent Contractor Agreement, dated as of February 1, 2014 (as amended from time to time, the “Consulting Agreement”). This Warrant and the Common Stock Warrant (Certificate
No.     ), dated as of June 2, 2014 issued by the Company to
                                 to purchase
         shares of Common Stock, are being issued pursuant to Section 6 hereof in exchange for and replace the Common Stock Warrant (Certificate No. C-_), dated
[November 20, 2013][June 1, 2014] (the “Original Issuance Date”), issued by the Company to                      to purchase
         shares of Common Stock (the “Original Warrant”) after which the Original Warrant will be cancelled and be of no further force and effect. All Warrant Shares issued under this Warrant
pursuant to the Consulting Agreement are referred to herein, collectively, as the “Warrants.” 
 1. Manner of Exercise;
Expiration Date. 
 (a) This Warrant shall be exercisable in accordance with this Section 1 and Section 2 below
from and after the date hereof until 5:00 p.m., New York time on the fifth (5th) anniversary of the Original Issuance Date (the “Exercise Period”). The Holder may from time to time during the Exercise Period on any business day exercise
this Warrant, for all or any part of the Warrant Shares purchasable at such time hereunder, by delivering to the Company at its principal office (i) a written notice of the Holder’s election to exercise this Warrant (an “Exercise
Notice”), which Exercise Notice shall be irrevocable and shall specify the number of Warrant Shares to be purchased, (ii) payment of the aggregate Exercise Price for the applicable number of Warrant Shares to be purchased by check or wire
transfer of immediately available funds to an account then specified by the Company and (iii) this Warrant (the date on which the foregoing items are delivered to the Company being hereinafter referred to as the “Exercise Date”). Such
Exercise Notice shall be in the form of Annex A hereto, duly executed by the Holder or its duly authorized agent. 

  
 1 

 (b) Upon receipt of the items specified in Section 1(a), the Company
shall execute (or cause to be executed) and deliver (or cause to be delivered) to the Holder a certificate or certificates representing the aggregate number of full Warrant Shares issuable upon such exercise. This Warrant shall be deemed to have
been exercised and such certificate or certificates shall be deemed to have been issued, and the Holder shall be deemed to have become a Holder of record of such shares for all purposes, as of the Exercise Date. 

(c) If this Warrant is exercised in part, the Company shall, at the time of delivery of the certificate or certificates
representing the Warrant Shares being issued, deliver to the Holder a new Warrant evidencing the rights of the Holder to purchase the unpurchased Warrant Shares called for by this Warrant. Such new Warrant shall in all other respects be identical to
this Warrant. 
 (d) The Company shall pay any and all issue and other taxes (other than income taxes) that may be payable in
respect of the issuance of this Warrant or any issuance or delivery of Warrant Shares on exercise of this Warrant; provided, however, that the Company shall not be obligated to pay any transfer taxes resulting from any transfer requested by the
Holder of record of this Warrant in connection with any such exercise. 
 (e) The Company shall at all times reserve and keep
available out of its authorized but unissued shares of capital stock, solely for the purpose of effecting the exercise of this Warrant, such number of its shares of capital stock as shall from time to time be sufficient to effect such exercise of
this Warrant for the maximum number of shares of such class or series of capital stock issuable upon exercise of this Warrant; and if at any time the number of authorized but unissued shares of such capital stock shall not be sufficient to effect
such exercise of this Warrant for the maximum number of shares of such capital stock then issuable upon exercise hereunder, the Company will take such corporate action as may, in the opinion of its counsel, be necessary to increase its authorized
but unissued shares of such capital stock to such number of shares as shall be sufficient for such purpose, including, without limitation, engaging in best efforts to obtain the requisite stockholder approval of any necessary amendment to the
Company’s Certificate of Incorporation (as amended from time to time). The Company will not at any time close its stock transfer books in a manner which prevents the timely exercise of this Warrant. 

(f) If the Holder has not exercised this Warrant prior to the closing of a Corporate Transaction (as defined below) or in
connection with a Corporation Transaction as provided in Section 12, this Warrant shall automatically be deemed to be exercised in full in the manner set forth in Section 2, without any further action on behalf of the Holder, immediately
prior to such closing. In such case, if the fair market value of one share of Common Stock is less than the Exercise Price (at the date of calculation as set forth in Section 2), this Warrant will be deemed to be terminated without any further
payment. “Corporate Transaction” shall mean (A) the closing of the sale, transfer or other disposition of all or substantially all of the Company’s assets, (B) the consummation of the merger or consolidation of the
Company with or into another entity (except a merger or consolidation in which the holders of capital stock of the Company immediately prior to such merger or consolidation continue to hold at least 50% of the voting power of the capital stock of
the Company or the surviving or acquiring entity), (C) the closing of the transfer (whether by merger, consolidation or otherwise), in one transaction or a series of related transactions, to a person or group of affiliated persons (other than an
underwriter of this corporation’s securities), of the Company’s securities if, after such closing, such person or group of 

  
 2 

 affiliated persons would hold 50% or more of the outstanding voting stock of this
corporation (or the surviving or acquiring entity), (D) an Initial Public Offering (as defined below) of the Company or (E) a liquidation, dissolution or winding up of this corporation; provided, however, that a transaction shall not constitute
a Corporate Transaction if its sole purpose is to change the state of the Company’s incorporation or to create a holding company that will be owned in substantially the same proportions by the persons who held the Company’s securities
immediately prior to such transaction. Notwithstanding the prior sentence, the sale of shares of the Company’s preferred stock in a bona fide financing transaction shall not be deemed a “Corporate Transaction. 

2. Net Exercise Issue. Notwithstanding any provision herein to the contrary, if the fair market value of one share of Common Stock is
greater than the Exercise Price (at the date of calculation as set forth below), in lieu of exercising this Warrant for cash, the Holder may elect to receive shares equal to the value (as determined below) of this Warrant (or the portion thereof
being canceled) by surrender of this Warrant at the principal office of the Company together with the properly endorsed Exercise Notice in which event the Company shall issue to the Holder a number of shares of Common Stock computed using the
following formula: 
 X = Y (A-B) 

A 
 Where X =
    the number of Warrant Shares to be issued to the Holder 
 Y =     the number of Warrant Shares
with respect to which this Warrant is being exercised 
 A =     the fair market value of one share of Common Stock (at
the date of such calculation) 
 B =     Exercise Price (as adjusted to the date of such calculation) 

For purposes of the above calculation, (a) if the Company has consummated a sale of shares of its equity securities in a bona fide firm
commitment underwritten public offering pursuant to a registration statement on Form S-1 (or a successor form) under the Securities Act (an “Initial Public Offering”), then the fair market value of
one share of Common Stock shall be valued at the volume weighted average price of the Common Stock for the 30 trading days immediately prior to the Exercise Date, as reported by Bloomberg; or (b) if the Company has not consummated an Initial Public
Offering, then the fair market value shall be determined in good faith by the Board of Directors of the Company. 
 3. Adjustment of
Exercise Price and Number of Conversion Shares. 
 (a) Adjustments for Stock Dividends, Splits, etc. If the
Company declares or pays a dividend on the outstanding shares of the Common Stock or other securities, then upon exercise of this Warrant, for each Warrant Share acquired, Holder shall receive, without cost to Holder, the total number and kind of
securities to which Holder would have been entitled had Holder owned the Warrant Shares of record as of the date the dividend occurred. If the Company subdivides the outstanding shares of Common Stock by reclassification or otherwise into a greater
number of shares, the number of Warrant Shares purchasable hereunder shall be proportionately increased and the Warrant Price shall be proportionately decreased. If the outstanding shares of Common Stock are combined or consolidated, by
reclassification or otherwise, into a lesser number of shares, the Warrant Price shall be proportionately increased and the number of Warrant Shares shall be proportionately decreased. 

  
 3 

 (b) Reclassification, Reorganization and Consolidation. In case of
any reclassification, capital reorganization or change in the capital stock of the Company, then, as a condition of such reclassification, reorganization or change, lawful provision shall be made, and duly executed documents evidencing the same from
the Company or its successor shall be delivered to the Holder, so that the Holder shall have the right at any time prior to the expiration of this Warrant to purchase, at a total price equal to that payable upon the exercise of this Warrant, the
kind and amount of shares of stock and other securities or property receivable in connection with such reclassification, reorganization or change by a holder of the same number and type of securities as were purchasable as Warrant Shares by the
Holder immediately prior to such reclassification, reorganization or change. In any such case appropriate provisions shall be made with respect to the rights and interest of the Holder so that the provisions hereof shall thereafter be applicable
with respect to any shares of stock or other securities or property deliverable upon exercise hereof, and appropriate adjustments shall be made to the Exercise Price per Warrant Share payable hereunder, provided the aggregate Exercise Price
shall remain the same. 
 4. Fractional Shares. No fractional Warrant Shares shall be issuable upon exercise or conversion of the
Warrant and the number of Warrant Shares to be issued shall be rounded up to the nearest whole Warrant Share. 
 5. Replacement of
Warrant. On receipt of evidence reasonably satisfactory to the Company of the loss, theft, destruction or mutilation of this Warrant and, in the case of any such loss, theft or destruction of this Warrant, on delivery of an indemnity agreement
reasonably satisfactory in form and amount to the Company or, in the case of any such mutilation, on surrender and cancellation of this Warrant, the Company at its expense will execute and deliver, in lieu thereof, a new Warrant of like tenor. 

6. Negotiability, etc. This Warrant is issued upon the following terms, all of which the Holder hereof by the taking hereof consents and
agrees: 
 (a) The Holder shall not be entitled to pledge, mortgage, transfer, endorse or otherwise convey this Warrant (a
“Transfer”), in whole or in part, without with the prior written consent of the Company, other than to Affiliates (as defined below). To the extent permitted by the preceding sentence, the Holder and its direct and indirect transferees may
Transfer all or any portion of this Warrant by surrendering this Warrant to the Company together with a completed assignment in the form attached hereto as Annex B. Upon such surrender, the Company shall deliver a new Warrant or Warrants to
the person or persons entitled thereto and, if applicable, shall deliver to Holder a new Warrant evidencing the right of Holder to purchase the balance of the Warrant Shares subject to purchase hereunder. The term “Holder” as used herein
shall include any transferee to whom this Warrant has been Transferred in accordance with this Section 6. The term “Affiliate” as used herein means, with respect to any Holder, any other person or entity who, directly or indirectly,
controls, is controlled by, or is under common control with such Holder, including without limitation any general partner, managing member, limited partner, officer or director of such Holder or any venture capital fund now or hereafter existing
that is controlled by one or more general partners or managing members of, or shares the same management company with, such Holder. 

  
 4 

 (b) The Holder shall not be entitled to vote or to receive dividends or to
be deemed the Holder of capital stock that may at any time be issuable upon exercise of this Warrant for any purpose whatsoever, nor shall anything contained herein be construed to confer upon the Holder any of the rights of a stockholder of the
Company or any right to vote for the election of directors or upon any matter submitted to stockholders at any meeting thereof, or to give or withhold consent to any corporate action (whether upon any recapitalization, issuance or reclassification
of stock, change of par value or change of stock to no par value, consolidation, merger or conveyance or otherwise), or to receive notice of meetings, or to receive dividends or subscription rights, until the Holder shall have exercised this Warrant
and been issued shares of capital stock in accordance with the provisions hereof. 
 (c) Neither this Warrant nor any shares
of capital stock or other securities purchased pursuant to this Warrant have been registered under the Securities Act and applicable state securities laws. Therefore, the transfer or exchange of this Warrant or such shares may be made only in a
transaction permitted under the Securities Act and applicable state securities laws or pursuant to an exemption therefrom. Prior to registration, the certificates evidencing the Warrant Shares or other securities issued on the exercise of this
Warrant shall bear a legend to the effect that the shares evidenced by such certificates have not been registered under the Securities Act and applicable state securities laws. 

(d) Until this Warrant is transferred on the books of the Company, the Company may treat the registered Holder hereof as the
absolute owner hereof for all purposes, notwithstanding any notice to the contrary. 
 7. Notices, etc. All notices and other
communications from the Company to the Holder of this Warrant shall be sent by electronic transmission or overnight courier or shall be mailed by first class registered or certified mail, postage prepaid, at such address as may have been furnished
to the Company in writing by such Holder or, until any such Holder furnishes to the Company an address, then to, and at the address of, the last Holder of this Warrant who has so furnished an address to the Company. All such notices and
communications shall, when mailed, be effective when deposited in the mails and, when sent by electronic transmission or overnight courier, delivered, be effective when received. 

8. Amendments. This Warrant and any term hereof may be changed, waived, discharged or terminated only by an instrument in writing signed
by the party against which enforcement of such change, waiver, discharge or termination is sought. 
 9. Governing Law. This Warrant
shall be construed and enforced in accordance with and governed by the laws of the State of Delaware without regard to the laws that might be applied under any conflict of laws principles. 

10. Headings. The headings in this Warrant are for purposes of reference only, and shall not limit or otherwise affect any of the terms
hereof. 
 11. Severability. The invalidity or unenforceability of any provision hereof shall in no way affect the validity or
enforceability of any other provision. 
 12. Assumption of Warrant. Subject to Section 1(f), if at any time while this Warrant,
or any portion thereof, is outstanding and unexpired there shall be a Corporate Transaction, then, as a part of such transaction, the Company shall provide notice to the Holder prior to the closing of such Corporate Transaction and lawful provision
shall be made so that the Holder shall be entitled to receive upon exercise of this Warrant, during the period specified herein and upon payment of the Exercise Price then in effect, the 

  
 5 

 number of shares of stock or other securities or property of the successor corporation resulting from the
Corporate Transaction which a holder of the shares deliverable upon exercise of this Warrant would have been entitled to receive in such Corporate Transaction if this Warrant had been exercised immediately before such Corporate Transaction, all
subject to adjustment as provided in Section 3. If the Holder does not exercise this Warrant pursuant to this Section 12 prior to the closing of a Corporate Transaction, then Section 1(f) shall apply. 

[END OF TEXT. SIGNATURE PAGE FOLLOWS.] 

  
 6 

 IN WITNESS WHEREOF, the Company has caused this Warrant to be executed by a duly authorized
officer as of the date first written above. 
  

			
	CENTREXION CORPORATION
		
	By:	 	
                     

	Name:
	Title:	 	

  

			
	ACCEPTED AND AGREED:
		
	By:	 	
                     

	Name:	 	
	Title:	 	

  
 [Signature Page to
Common Stock Warrant] 

 Annex A 

Form of Exercise Notice 
 (To be executed if
Holder desires to exercise the Warrants evidenced by this Warrant Certificate). 
 TO CENTREXION CORPORATION 

 

	 	❑	 The undersigned hereby (1) irrevocably elects to exercise
                    Warrant Shares represented by this Warrant to purchase
                    shares of Common Stock issuable upon the exercise of such Warrant, (2) makes payment in full of the aggregate Exercise Price
for such Warrants by enclosure of a certified or bank cashier’s check therefor, upon condition that a new Warrant be issued for the balance of the Warrant Shares remaining, if any, and (3) requests that a certificate for the shares of
Common Stock purchased hereunder be issued in the name of and delivered to: 

 (Please print name and address) 

 

	 	❑	 The undersigned hereby elects to convert
                                    percent
(        %) of the value of the Warrant pursuant to the provisions of Section 2 of the Warrant. 

If such number of Warrant Shares not be all of the Warrant Shares evidenced by this Warrant Certificate, a new Warrant for the balance remaining of such
Warrant Shares shall be registered in the name of and delivered to: 
 (Please print name and address) 

 

			
	Dated: 	 	
                     

		
	Signature:	 	
                     

  
 8 

 Annex B 

Form of Assignment 
 (To be executed by the
registered Holder if such Holder desires to transfer the attached Warrant.) 
 FOR VALUE RECEIVED,
                                        
hereby sells, assigns, and transfers
unto                                         a
Warrant to purchase     shares of Common Stock, par value $0.001 per share, of Centrexion Corporation, a Delaware corporation (the “Company”), together with all right, title, and interest therein, and does
hereby irrevocably constitute and appoint                     attorney to transfer such Warrant on the books of the Company, with full power
of substitution. 
 The undersigned represents, unless the sale of this Warrant has been registered under the Securities Act of 1933, as
amended (the “Securities Act”), that the undersigned is acquiring such Warrant for its own account for investment and not with a view to or for sale in connection with any distribution thereof (except for any resale pursuant to a
Registration Statement under the Securities Act). 
  

			
	Dated: 	 	
                     

		
	Signature:	 	
                     

  
 9

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