Document:

Exhibit 10.56

 Exhibit 10.56 
  
 AMENDMENT NO. 1 to 
  
 AMENDED AND RESTATED DIRECTOR DESIGNATION AGREEMENT 
  
 This Amendment No. 1 dated as of September 9, 2003 (this “Amendment”) to the Amended and Restated Director Designation Agreement dated as
of January 28, 2003 (the “Current Agreement”, and as amended by this Amendment, the “Agreement”), is hereby entered into by and among XM Satellite Radio Holdings Inc., a corporation duly organized under the
laws of the State of Delaware (the “Company”); Clear Channel Investments, Inc., a corporation duly organized under the laws of the State of Nevada (“Clear Channel”); Hughes Electronics Corporation, corporation duly
organized under the laws of Delaware (“Hughes”); American Honda Motor Co., Inc., a corporation duly organized under the laws of the State of California (“Honda”); and Madison Dearborn Capital Partners III, L.P.
(“Madison Capital”), Madison Dearborn Special Equity III, L.P. (“Madison Equity”), and Special Advisors Fund I, LLC (“Madison Advisors” and, collectively with Madison Capital and Madison Equity,
each an entity duly organized under the laws of the State of Delaware, “Madison”). Clear Channel, Honda, Hughes and Madison are collectively referred to herein as the “Investors.” The Company and the Investors are
collectively referred to herein as the “Parties.” AEA XM Investors I LLC, AEA XM Investors II LLC, AEA XM Investors IA LLC and AEA XM Investors IIA LLC, each a limited liability company organized under the laws of the State of
Delaware (individually or collectively “AEA XM”) are becoming parties hereto solely for the purposes of agreeing to the amendment of the Current Agreement by this Amendment and terminating their respective rights and obligations
thereunder. Upon effectiveness of this Amendment, each of AEA XM Investors I LLC, AEA XM Investors II LLC, AEA XM Investors IA LLC and AEA XM Investors IIA LLC shall cease to be a party to the Agreement and all of their respective rights and
obligations thereunder shall be terminated. 
  
 WITNESSETH

  
 WHEREAS, the Company, the Investors, and AEA XM are parties to
the Current Agreement, dated as of January 28, 2003, that relates to the designation of the Company’s directors; and 
  
 WHEREAS, AEA XM desires to cease to be party to the Current Agreement and to cease to have any right that its designee be elected to the Company’s
Board of Directors; and 
  
 WHEREAS, the Company and each of the
Investors believe it to be in the best interests of the Company and the mutual best interests of each of the Investors to continue to have certain agreements with respect to the designation of directors of the Company. 
  
 NOW, THEREFORE, in consideration for the mutual covenants contained herein,
the adequacy, receipt, and sufficiency of which are hereby acknowledged, the undersigned hereby agree as follows: 

 ARTICLE I. 
  
 DEFINITIONS 
  
 Section 1.1 Capitalized terms used but not otherwise defined herein shall have the receptive meanings as set forth in the Current Agreement. All
references to the “Agreement” in the Current Agreement, as amended, shall be deemed to refer to the Current Agreement, as amended, supplemented or otherwise modified from time to time. 
  
 ARTICLE II. 
  
 AMENDMENT OF ARTICLE II 
  
 Section 2.1 (a) Section 2.1 (a) of the Current Agreement is hereby amended by
deleting Section 2.1(a)(v) thereof and substituting therefor the phrase “[Intentionally Deleted]” 
  
 (b) Section 2.1(b) of the Current Agreement is hereby amended by deleting the third sentence thereof relating to the rights of AEA XM. 
  
 (c) Section 2.4 of the Current Agreement is hereby deleted in its entirety
and the following substituted therefor: 
  
 Section 2.4 Partial Termination. If the Investors at any time beneficially own in excess of 50% of the voting securities of the Company, then this Agreement shall terminate automatically as to the following, in all respects,
first, Clear Channel, and second (if necessary), Madison, until the remaining Investors beneficially own 50% or less of the voting securities of the Company. The Parties shall take all actions to reflect any such partial termination as may be
reasonably requested by the Company or any other Party. Thirty (30) days prior to a date for payment of interest (an “Interest Payment”) under any of (i) the New Notes, (ii) the 10% Senior Secured Convertible Note due 2009 of the Company
and XM Satellite Radio Inc. in favor of General Motors Corporation, and (iii) the Credit Agreement among the Company, XM Satellite Radio Inc. and General Motors Corporation, the Company shall calculate the Investors’ beneficial ownership of
voting securities of the Company (with a copy of such calculation to be furnished to each of the Investors). Each Investor shall provide the Company with at least ten (10) days prior written notice of its intent to purchase any voting securities of
the Company. If any proposed purchase of voting securities or Interest Payment would cause the beneficial ownership of the Investors to be in excess of 50%, then the Parties shall take such actions as necessary to remove Investors as Parties to this
Agreement in the order set forth above. 
  
 (d) Schedule I of
the Current Agreement is hereby amended by deleting the name, address and facsimile number of AEA XM. 
  

 - 2 - 

 ARTICLE III. 
  
 MISCELLANEOUS 
  
 Section 3.1 GOVERNING LAW. THIS AGREEMENT SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF DELAWARE WITHOUT GIVING
EFFECT TO ANY CONFLICT OF LAW PROVISIONS THEREOF. 
  
 EACH OF THE
PARTIES ACKNOWLEDGES THAT (i) IT IS A KNOWLEDGEABLE, INFORMED, SOPHISTICATED BUSINESS ENTITY CAPABLE OF UNDERSTANDING AND EVALUATING THE PROVISIONS SET FORTH IN THIS AGREEMENT, AND (ii) IT HAS BEEN REPRESENTED BY SUCH COUNSEL AND OTHER ADVISORS OF
ITS CHOOSING AS IT HAS DEEMED APPROPRIATE IN CONNECTION WITH ITS DECISION TO ENTER INTO THIS AGREEMENT. 
  
 Section 3.2 Parties In Interest. This Agreement shall be binding upon and shall inure to the benefit of each Party and their respective successors
and permitted assigns as provided for herein, and by their signatures hereto, and each Party intends to and does hereby become bound. Nothing expressed or mentioned in this Agreement is intended or shall be construed to give any Person other than
the Parties hereto and their respective successors and assigns any legal or equitable right, remedy or claim under or in or in respect of this Agreement or any provision herein contained. 
  
 Section 3.3 Severability of Provisions. In case any one or more of the provisions contained in this Agreement should
be invalid, illegal or unenforceable in any respect, the validity, legality and enforceability of the remaining provisions contained herein shall not in any way be affected or impaired thereby. 
  
 Section 3.4 Plural; Singular. When used herein, the singular of each
term includes the plural and the plural of each term includes the singular. 
  
 Section 3.5 Counterparts. This Agreement may be executed in any number of counterparts all of which taken together shall constitute one agreement and any Party hereto may execute this Agreement by signing any
such counterpart. 
  
 Section 3.6 Descriptive Headings. The
descriptive headings of the several sections of this Agreement are inserted for convenience only and do not constitute a part of this Agreement. 
  
 Section 3.7 Future Assurances. Each Party shall execute and deliver all such future instruments and take such other and further action as may be
reasonably necessary or appropriate to carry out the provisions of this Agreement and the intention of the Parties as expressed herein. 
  
 Section 3.8 Continued Validity of Agreement. The Current Agreement, as amended by this Amendment, shall continue in full force and effect among the
Parties. 
  
 Section 3.9 Fees and Expenses. The Company shall pay
the reasonable legal fees and expenses of the Investors incurred in connection herewith. 
  

 - 3 - 

 Section 3.9 Fees and Expenses. The Company shall pay the reasonable legal fees and expenses of the
Investors incurred in connection herewith. 
  

 - 4 - 

 Exhibit 10.56 
  
 IN WITNESS WHEREOF, the Parties have caused this Agreement to be duly signed as of the date first above written. 
  

	 XM SATELLITE RADIO HOLDINGS INC.

		
	By:	 	  

	 Name:

	 Title:

  

	 CLEAR CHANNEL INVESTMENTS, INC.

		
	By:	 	  

	 Name:

	 Title:

  

	 HUGHES ELECTRONICS CORPORATION

		
	By:	 	  

	 Name:

	 Title:

  

	 AMERICAN HONDA MOTOR CO., INC.

		
	By:	 	  

	 Name:

	 Title:

	 MADISON DEARBORN CAPITAL PARTNERS III, L.P.
	 	 	 	 MADISON DEARBORN SPECIAL EQUITY III, L.P.

	 By Madison Dearborn Partners III, L.P., its general partner
	 	 	 	 By Madison Dearborn Partners III, L.P., its general partner

	 By Madison Dearborn Partners LLC, its general partner
	 	 	 	 By Madison Dearborn Partners LLC, its general partner

					
	By:	 	  

	 	 	 	By:	 	  

	 Name:
	 	 	 	Name:
	 Title:
	 	 	 	Title:
				
	 SPECIAL ADVISORS FUND I, LLC
	 	 	 	 	 	 
	 By Madison Dearborn Partners III, L.P., its manager
	 	 	 	 	 	 
	 By Madison Dearborn Partners LLC, its general partner
	 	 	 	 	 	 
					
	 By:
	 	  

	 	 	 	 	 	 
	 Name:
	 	 	 	 	 	 
	 Title:
	 	 	 	 	 	 

  

	 AEA XM INVESTORS I LLC
	 	 	 	 AEA XM INVESTORS II LLC

	 By AEA XM Investors I LP, its Sole Member
	 	 	 	 By AEA XM Investors II LP, its Sole Member

	 By AEA XM Investors Inc., its General Partner
	 	 	 	 By AEA XM Investors Inc., its General Partner

					
	 By:
	 	  

	 	 	 	 By:
	 	  

	 Name:
	 	 	 	 Name:

	 Title:
	 	 	 	 Title:

			
	 AEA XM INVESTORS IA LLC
	 	 	 	 AEA XM INVESTORS IIA LLC

	 By AEA XM Investors IA LP, its Sole Member
	 	 	 	 By AEA XM Investors IIA LP, its Sole Member

	 By AEA XM Investors Inc., its General Partner
	 	 	 	 By AEA XM Investors Inc., its General Partner

					
	 By:
	 	  

	 	 	 	By:	 	  

	 Name:
	 	 	 	Name:
	 Title:
	 	 	 	Title:

  

 - ii -SEPARATION AGREEMENT WITH RICHARD LABAUDINIERE, DATED JULY 9, 2003

 Exhibit 10.1 
  
 July 9, 2003 
  
 Richard Labaudiniere, PhD. 
 258 Western Avenue 
 Sherborn, MA 01770 
  
 Dear Richard: 
  
 We have mutually agreed that, due to a strategic shift which will result in a discontinuation of discovery research, it is
appropriate for there to be a transition and a termination of your employment with Genome Therapeutics Corp. (the “Company”) no later than December 31, 2003. The purpose of this letter is to confirm the agreement between you and the
Company concerning the remainder of your employment and your separation arrangements, as follows: 
  
 1. Remaining Period of Employment and Employment Termination. 
  
 (a) The Company will continue to employ you in your current position, at your current base rate of pay (i.e., at the rate of $260,866 per
year), and will continue your participation in those of its benefit plans in which you are currently enrolled, during the remainder of your employment with the Company. 
  
 (b) You agree to work diligently to accomplish the goals to which you and the Company have agreed (as set
forth on Attachment A to this Agreement) and to otherwise cooperate to assure a smooth winding down or transition, as applicable, of your duties and responsibilities for the Company. You will continue to provide services on a full-time basis
until the termination of your employment, unless a reduced work schedule is mutually agreed by you and the Company. 
  
 (c) Your employment with the Company will terminate on December 31, 2003 or such earlier date as the Company may designate (the
“Separation Date”). You hereby resign all positions and offices held with the Company or any of its Affiliates (as hereafter defined), effective as of the Separation Date. It is understood that the Company will take actions in reliance on
your resignation and that it is irrevocable. 
  
 2. Final Salary
and Vacation Pay. You will receive, no later than the Separation Date, pay for all work you have performed for the Company during the final payroll period of your employment, through the Separation Date, to the extent not previously paid. You will
also receive pay, no later than the Separation Date, for all vacation time you have earned but not used as of the Separation Date, as determined in accordance with the policies of the Company. 
  
 3. Severance Benefits. Provided that you meet your obligations under Section
1(b) and Section 7 hereof to the reasonable satisfaction of the Company and otherwise meet the conditions set forth herein, the Company will provide you the following severance benefits: 
  
 (a) The Company will pay you severance pay in an amount equal to six months of base salary. In addition, if
the Separation Date occurs prior to December 31, 2003, the Company will pay you an amount equal to your base salary for the period from the day immediately following the Separation Date through December 31, 2003. Both payments will be made in a
single lump sum within fifteen (15) business days following the later of the effective date of the Release (as defined below) or the date the Release, signed by you, is received by the Company. 
  
 (b) Following the Separation Date, you and your eligible
dependents may continue participation in the Company’s group health and dental plans under the federal law known as COBRA. If you elect to do so then, for the from the day immediately following the Separation Date through September 30, 2004 or,
if sooner, the date you commence other employment, the Company will pay or reimburse you, at its option, for the premium cost of that participation; provided that you notify the Company promptly when you obtain other employment. After the Company
ceases to pay that premium cost, you and your 

 eligible dependents may continue participation for any remaining period permitted under COBRA by paying
the full premium cost plus a small administrative fee. 
  
 (c) The Company will pay you a bonus for 2003 of up to thirty percent (30%) of your base salary in cash, with the actual amount of the bonus to be determined by the Company, in its discretion, based on its assessment of your achievement of
the goals set forth on Attachment A. The bonus will be payable at the time payment is made to you under Section 3(a) above. 
  
 (d) To assist you in your search for other employment, the Company will provide you an additional lump sum payment in the amount of
$8,500, payable at the time payment is made to you under Section 3(a) above. 
  
 (e) Any stock options granted to you by the Company which are not exercisable on the Separation Date and not then exercised, expired or cancelled, shall continue to vest during the period from the Separation Date
through December 31, 2004. You may exercise any stock options granted to you that have vested on or before December 31, 2004, provided that you do so no later than March 31, 2005. Any stock options that remain unvested on December 31, 2004 shall be
cancelled as of that date. Any vested stock options that are not exercised by March 31, 2005 shall then be cancelled. Your elections under this Section 3(e), including without limitation your decision to delay the exercise of options vested on the
Separation Date to a date more than three months from the Separation Date, may have tax consequences and the Company recommends that you consult your tax advisor. 
  
 (f) As a condition of your eligibility to receive the benefits set forth in Sections 3(a) through 3(e)
above, you must sign and return the release of claims included here as Attachment B (the “Release”), no sooner than the day immediately following the Separation Date and no later than 21 days thereafter, and having signed and
returned the Release, you must not revoke it thereafter. The Release creates legally binding obligations and the Company advises you to consult an attorney before signing it. 
  
 4. Withholding. All payments made by the Company under this Agreement shall be reduced by any tax or other amounts required
to be withheld by the Company under applicable law. 
  
 5.
Acknowledgement of Full Payment. You acknowledge and agree that the payments provided under Sections 1 and 2 of this Agreement are in complete satisfaction of any and all compensation due to you from the Company or any of its Affiliates, whether for
services provided or otherwise, through the Separation Date and that, except as expressly provided under this Agreement, no further compensation of any kind, in cash or equity or otherwise, is owed to you. 
  
 6. Status of Employee Benefits and Paid Time Off. Except as otherwise
expressly provided in Section 3(b) of this Agreement, your participation in all employee benefit plans of the Company will end as of the Separation Date, in accordance with the terms of those plans. You will not continue to earn vacation or other
paid time off after the Separation Date. 
  
 7. Continuing
Obligations. You agree to continue to honor all of your obligations under the agreement captioned “Invention Assignment, Non-Disclosure and Covenant Not to Compete” which you entered into with the Company on April 5, 2001. You also agree
not to disparage the Company or its Affiliates, their business, products or management, publicly or to Company employees or to those with whom the Company does business. 
  
 8. Cooperation with regard to Litigation. You agree, during the remainder of your employment and thereafter, to reasonably
cooperate with the Company with respect to all matters arising during or related to your employment with the Company, including without limitation all matters in connection with any governmental investigation, litigation or regulatory or other
proceeding which may have arisen or which may arise following the signing of this Agreement. The Company will reimburse your out-of-pocket expenses incurred in complying with its requests hereunder in accordance with the policies of Company
governing reimbursement of business expenses, as in effect from time to time. In addition, for all time spent complying with your obligations under this Section 8 at the request of the Company after the Separation Date, other than time spent in
giving testimony, the Company will pay you at the rate of $275 per hour. 

 9. Definition of Affiliates. For purposes of this Agreement, “Affiliates” means all persons and
entities directly or indirectly controlling, controlled by or under common control with the Company, where control may be by management authority, equity interest or otherwise. 
  
 10. Change of Control. In the event that the Company experiences a Change of Control as defined in Exhibit A of the June 15,
2001 employment agreement prior to your Separation Date but subsequent to the execution of this Agreement, the Change of Control provisions contained in the June 15, 2001 agreement and subsequent amendment will remain in force until the Separation
Date and supercede the compensation and benefits provisions outlined in this Agreement. 
  
 11. Complete Agreement and Amendment. With the exception of Section 10, this Agreement constitutes the entire agreement between you and the Company and replaces all prior and contemporaneous agreements, communications
sand understandings, whether oral or written, with respect to your employment and its termination and all related matters, including the letter agreement between you and the Company concerning your employment amended and restated as of February 27,
2003, but excluding the Invention Assignment, Non-Disclosure and Covenant Not to Compete to which reference is made in Section 7 above. This Agreement may not be modified or amended, and no breach shall be deemed to be waived, unless agreed to in
writing by you and the Chief Executive Officer of the Company or his expressly authorized designee. 
  
 12. Captions and Counterparts. The captions and headings in this Agreement are for convenience only and in no way define or describe the scope or content
of any provision of this Agreement. This Agreement may be signed in two or more counterparts, each of which shall be an original and all of which together shall constitute one and the same instrument. 

 If the terms of this Agreement are acceptable to you, please promptly sign, date and return it to me. At
the time you sign and return it, this letter will take effect as a legally-binding agreement between you and the Company on the basis set forth above. You can elect to sign this agreement prior to Separation Date and exercise your prerogative to
waive the consideration and revocation period. The enclosed counterpart of this Agreement, which you should also sign and date, is for your own records. 
  

	 Sincerely,
 GENOME THERAPEUTICS CORPORATION

		
	By:	 	/s/ Joseph A. Pane
	 	

		
	Title:	 	Vice President Human Resources
	 	

		
	Date:	 	7/9/2003
	 	

  

	 Accepted and agreed:

		
	Signature:	 	/s/ Richard Labaudiniere
	 	

	 	 	Richard Labaudiniere
		
	Date:	 	7/9/2003
	 	

 ATTACHMENT A 

 ATTACHMENT B 
  
 RELEASE OF CLAIMS 
  
 FOR AND IN CONSIDERATION OF the severance benefits to be provided me in connection with the termination of my employment, as set forth in the letter
agreement between me and Genome Therapeutics Corporation (the “Company”) dated July, 2003 (the “Agreement”), which are conditioned on my signing this Release of Claims and to which I am not otherwise entitled, and for other good
and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, I, on my own behalf and on behalf of my heirs, executives, administrators, beneficiaries, representatives and assigns, and all others connected with me, hereby
release and forever discharge the Company and its Affiliates (as defined in the Agreement) and all of their respective past, present and future officers, directors, shareholders, employees, agents, general and limited partners, members, managers,
joint venturers, representatives, successors and assigns, and all others connected with any of them, both individually and in their official capacities, from any and all causes of action, rights and claims of any type or description, whether known
or unknown, which I have had in the past, now have, or might now have, through the date of my signing of this Release of Claims, in any way resulting from, arising out of or connected with my employment by the Company or any of its Affiliates or the
termination of that employment or pursuant to any federal, state or local law, regulation or other requirement (including without limitation Title VII of the Civil Rights Act of 1964, the Age Discrimination in Employment Act, the Americans with
Disabilities Act, and the fair employment practices laws of the state or states in which I have been employed by the Company or any of its Affiliates, each as amended from time to time). 
  
 Excluded from the scope of this Release of Claims are (i) any claim arising under the terms of the Agreement after the
effective date of this Release of Claim and (ii) any right of indemnification or contribution that I have pursuant to the Articles of Incorporation or By-Laws of the Company or any of its Affiliates. 
  
 In signing this Release of Claims, I acknowledge my understanding that I may
not sign it prior to the termination of my employment, but that I may consider the terms of this Release of Claims for up to twenty-one (21) days from the date my employment with the Company terminates. I also acknowledge that I am advised by the
Company to seek the advice of an attorney prior to signing this Release of Claims; that I have had sufficient time to consider this Release of Claims and to consult with an attorney, if I wished to do so, or to consult with any other person of my
choosing before signing; and that I am signing this Release of Claims voluntarily and with a full understanding of its terms. 
  
 I further acknowledge that, in signing this Release of Claims, I have not relied on any promises or representations, express or implied, that are not set
forth expressly in the Agreement. I understand that I may revoke this Release of Claims at any time within seven (7) days of the date of my signing by written notice to the President of the Company and that this Release of Claims will take effect
only upon the expiration of such seven-day revocation period and only if I have not timely revoked it. 
  
 Intending to be legally bound, I have signed this Release of Claims under seal as of the date written below. 
  

		
	Signature:	 	 
	 	

	 	 	Richard Labaudiniere, PhD
		
	Date Signed:

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