Document:

Ex-10.42

 Exhibit 10.42 
 2012 and 2013 Executive Officer Compensation Arrangements 
 The
compensation for the executive officers of Cerus Corporation regarding annual base salaries and target bonus percentages were as follows: 
  

																	
	 Name
	  	2012
Annual Base
Salary
(1)	 	  	2012
Targeted Bonus
(as a % of 2011
Annual Base
Salary)	 	 	2013
Annual Base
Salary
(2)	 	  	2013
Targeted Bonus
(as a % of 2012
Annual Base
Salary)	 
	 William M. Greenman

President and Chief Executive Officer 
	  	$	475,000	  	  	 	60	% 	 	$	500,000	  	  	 	60	% 
	 Laurence M. Corash, M.D.

Senior Vice President, Chief Scientific Officer 
	  	$	390,113	  	  	 	35	% 	 	$	399,866	  	  	 	40	% 
	 Howard G. Ervin (3)
 Vice President, Legal Affairs 
	  	$	327,295	  	  	 	35	% 	 	$	65,459	  	  	 	n/a	  
	 Chrystal N. Menard (4)
 Chief Legal Officer
	  	$	280,000	  	  	 	n/a	  	 	$	280,000	  	  	 	35	% 
	 Kevin D. Green

Vice President, Finance and Chief Financial Officer(5) 
	  	$	263,780	  	  	 	35	% 	 	$	279,607	  	  	 	35	% 
	 Caspar Hogeboom(6)
 President, Cerus Europe B.V.
	  	$	288,736	  	  	 	35	% 	 	$	303,871	  	  	 	40	% 

  

	(1)	Annual base salary was effective March 1, 2012, except for Ms. Menard, as discussed in footnote 4 below. 

 

	(2)	Annual base salary was effective March 1, 2013. 

  

	(3)	Mr. Ervin retired as the Chief Legal Officer effective December 3, 2012 and converted to part-time status, effective January 1, 2013.

  

	(4)	Ms. Menard’s annual base salary for 2012 was effective December 3, 2012. 

 

	(5)	Mr. Green’s title changed from Vice President, Finance and Chief Accounting Officer to Vice President and Chief Financial Officer effective February 28,
2013. 

  

	(6)	Mr. Hogeboom’s title changed from General Manager, Cerus Europe to President, Cerus Europe B.V., effective March 1, 2012. Mr. Hogeboom’s 2012
annual base salary of €224,540 has been converted from Euros to United States dollar by applying an average exchange rate of €1 to $1.2859 for the year ended December 31, 2012. Mr. Hogeboom’s 2013 annual base salary of
€230,153 has been converted from Euros to United States dollar using the exchange rate of €1 to $1.312, which was the exchange rate in effect on March 1, 2013.EX-10.13

 Exhibit 10.13 
 ACADIA Pharmaceuticals Inc. 
 Description of Outside Director
Compensation Program 
 The Board of Directors (the “Board”) of ACADIA Pharmaceuticals Inc. (“ACADIA”) has approved the
following fees that are payable to the non-management directors who are members of the Board, effective June 1, 2013: 
  

			
	 Annual
Retainer
	  	$35,000
	 Additional Retainer for Board Chair
	  	$22,500
	 Additional Retainer for Audit Chair
	  	$18,000
	 Additional Retainer for Audit Member (non-Chair)
	  	$9,000
	 Additional Retainer for Compensation Chair
	  	$14,000
	 Additional Retainer for Compensation
Member (non-Chair)
	  	$7,000
	 Additional Retainer for Nominating and Corporate Governance
Chair
	  	$10,000
	 Additional Retainer for Nominating and Corporate Governance Member
(non-Chair)
	  	$5,000
	
Options
	  	15,000 upon joining Board
	 	  	12,500 annual grant thereafter
	 	  	1,500 additional annual grant for Board
Chair

 The Annual Retainer amounts are payable following the first meeting of the Board that follows the annual meeting of
ACADIA’s stockholders. Annual option grants to directors are made at the Board meeting following the annual meeting of stockholders in accordance with the provisions of stock option plans that have been approved by ACADIA’s stockholders.
The annual retainer amount and annual option grant may be pro rated for a director that joins the Board other than at the first meeting of the Board following the annual meeting of stockholders. 

  
 1EX-10.33

 Exhibit 10.33 
 ACADIA Pharmaceuticals Inc. 
 Description of Executive Officer Annual
Incentive Cash Compensation Program 
 The Compensation Committee (the “Committee”) of the Board of Directors (the
“Board”) of ACADIA Pharmaceuticals Inc. (the “Company”) has recommended to the Board, and the Board has approved, incentive cash compensation for the Company’s executive officers pursuant to an annual incentive cash
compensation program. The program will provide for an annual incentive cash compensation target equal to a percentage of each executive’s base salaries as follows: 50% for Uli Hacksell, President and Chief Executive Officer; 35% for each of
Roger Mills, Executive Vice President, Development and Chief Medical Officer, and Thomas Aasen, Executive Vice President, Chief Financial Officer and Chief Business Officer; and 30% for Glenn Baity, Vice President & General Counsel.

 Under the program, after the completion of each fiscal year the Committee recommends to the Board for approval for each
executive a bonus that will be equal to an amount from 0 to 150% of the applicable target amount. In making its recommendations, the Committee assesses the level of achievement of specific criteria by the executive and the Company. These criteria
include the achievement of research and development milestones, including the advancement of the Company’s clinical programs and the Company’s preclinical assets toward clinical development; and other criteria the disclosure of which would
reveal confidential business information and plans of the Company.EX-10.34

 Exhibit 10.34 
 ACADIA PHARMACEUTICALS INC. 

CHANGE IN CONTROL SEVERANCE BENEFIT PLAN

  

	Section 1.	INTRODUCTION. 

 The ACADIA Pharmaceuticals Inc. Change in Control Severance Benefit Plan (the “Plan”) is hereby established effective March 11, 2013 (the “Effective
Date”). The purpose of the Plan is to provide for the payment of severance benefits to selected eligible employees of ACADIA Pharmaceuticals Inc. (the “Company”) in the event that such employees become subject to
involuntary or constructive employment terminations in connection with an acquisition of the Company. This Plan shall supersede any severance benefit plan, policy or practice previously maintained by the Company, except for an individually
negotiated employment contract or agreement between the Company and an employee. This Plan document also is the Summary Plan Description for the Plan. 
 For purposes of the Plan, the following terms are defined as follows: 
 (a)
“Affiliate” means any corporation (other than the Company) in an “unbroken chain of corporations” beginning with the Company, if each of the corporations other then the last corporation in the unbroken chain
owns stock possessing 50% or more of the total combined voting power of all classes of stock in one of the other corporations in such chain 
 (b) “Annual Base Salary” means the annualized base pay amount (excluding incentive pay, premium pay, commissions, overtime, bonuses, and other forms of variable
compensation) as in effect immediately prior to a Covered Termination and prior to any reduction that would give rise to an employee’s right to resign for Good Reason. 
 (c) “Average Annual Bonus” means: 
 (1) If
the Eligible Employee has been employed by the Company for the two complete calendar years that immediately precede the calendar year in which the Covered Termination occurs (the “Bonus Period”), the average of the annual
bonus amounts previously paid to the Eligible Employee or which have been earned by the Eligible Employee but remain unpaid in respect of performance during the Bonus Period, 
 (2) if the Eligible Employee has not been employed by the Company during the entire Bonus Period, but has been employed by the Company for a least one complete calendar year that precedes the year
in which the Covered Termination occurs, the average of the annual bonus amounts previously paid to the Eligible Employee or which have been earned by the Eligible Employee but remain unpaid in respect of performance during such calendar year(s); or

 (3) if the Eligible Employee has not been employed for at least one complete calendar year that precedes the calendar
year in which the Covered Termination occurs, the higher of: (i) the Target Bonus in effect for the calendar year in which the Covered Termination occurs; or (ii) the annualized target bonus amount in effect for the Eligible Employee for
the calendar year preceding the calendar year in which the Covered Termination occurs. 

  
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 (d) “Board” means the Board of Directors of the Company;
provided, however, that if the Board has delegated authority to administer the Plan to the Compensation Committee of the Board, then “Board” shall also mean the Compensation Committee. 

(e) “Cause” means, with respect to a particular employee, the occurrence of any of the following events:
(i) such employee’s attempted commission of, or participation in, a fraud or act of dishonesty against the Company; (ii) such employee’s intentional, material violation of any contract or agreement between the employee and the
Company or of any statutory duty owed to the Company; (iii) such employee’s unauthorized use or disclosure of the Company’s confidential information or trade secrets; (iv) such employee’s gross negligence or gross
misconduct; (v) such employee’s material failure to competently perform his/her assigned duties for the Company; (vi) sustained poor performance of any material aspect of the employee’s duties or obligations; or
(viii) employee’s conviction of, or the entry of a pleading of guilty or nolo contendere by such employee to, any crime involving moral turpitude or any felony; provided, in the case of clauses (v) and (vi), if such failure or poor
performance has not been substantially cured to the satisfaction of the Board within 30 days after written notice of such failure or poor performance has been given by the Company to the employee. The determination whether a termination is for Cause
shall be made by the Board in its sole and exclusive judgment and discretion. 
 (f) “Change in
Control” means the occurrence, in a single transaction or in a series of related transactions, of any one or more of the following events that also qualifies as a change in the ownership of the Company, a change in the effective control
of the Company, or a change in the ownership of a substantial portion of the assets of the Company (as these events are defined in Treasury Regulations Section § 1.409A-3(i)(5), or as these definitions may later be modified by other regulatory
pronouncements): 
 (1) any Exchange Act Person becomes the Owner, directly or indirectly, of securities of the Company
representing more than 50% of the combined voting power of the Company’s then outstanding securities other than by virtue of a merger, consolidation or similar transaction. Notwithstanding the foregoing, a Change in Control shall not be deemed
to occur (A) on account of the acquisition of securities of the Company by an investor, any affiliate thereof or any other Exchange Act Person that acquires the Company’s securities in a transaction or series of related transactions the
primary purpose of which is to obtain financing for the Company through the issuance of equity securities or (B) solely because the level of Ownership held by any Exchange Act Person (the “Subject Person”) exceeds the
designated percentage threshold of the outstanding voting securities as a result of a repurchase or other acquisition of voting securities by the Company reducing the number of shares outstanding, provided that if a Change in Control would occur
(but for the operation of this sentence) as a result of the acquisition of voting securities by the Company, and after such share acquisition, the Subject Person becomes the Owner of any additional voting securities that, assuming the repurchase or
other acquisition had not occurred, increases the percentage of the then outstanding voting securities Owned by the Subject Person over the designated percentage threshold, then a Change in Control shall be deemed to occur; 

(2) there is consummated a merger, consolidation or similar transaction involving (directly or indirectly) the Company and,
immediately after the consummation of such merger, consolidation or similar transaction, the stockholders of the Company immediately prior thereto do not Own, directly or indirectly, either (A) outstanding voting securities representing more
than 50% of the combined outstanding voting power of the surviving Entity in such merger, consolidation or similar transaction or (B) more than 50% of the combined outstanding voting power of the parent of the surviving Entity in such merger,
consolidation or similar transaction, in each case in substantially the same proportions as their Ownership of the outstanding voting securities of the Company immediately prior to such transaction; 

  
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 (3) the stockholders of the Company approve or the Board approves a plan of
complete dissolution or liquidation of the Company, or a complete dissolution or liquidation of the Company shall otherwise occur; 
 (4) there is consummated a sale, lease, exclusive and worldwide license, or other disposition of all or substantially all of the consolidated assets of the Company and its Subsidiaries, other than
a sale, lease, license or other disposition of all or substantially all of the consolidated assets of the Company and its Subsidiaries to an Entity, more than 50% of the combined voting power of the voting securities of which are Owned by
stockholders of the Company in substantially the same proportions as their Ownership of the outstanding voting securities of the Company immediately prior to such sale, lease, license or other disposition; or 

(5) individuals who, on Effective Date, are members of the Board (the “Incumbent Board”) cease for any
reason to constitute at least a majority of the members of the Board; provided, however, that if the appointment or election (or nomination for election) of any new Board member was approved or recommended by a majority vote of the members of the
Incumbent Board then still in office, such new member shall, for purposes of this Plan, be considered as a member of the Incumbent Board. 
 Notwithstanding the foregoing or any other provision of this Plan, the term Change in Control shall not include a sale of assets, merger or other transaction effected exclusively for the purpose of
changing the domicile of the Company. Once a Change in Control has occurred, no future events shall constitute a Change in Control for purposes of the Plan. 
 (g) “Closing” means the initial closing of the Change in Control as defined in the definitive agreement executed in connection with the Change in Control. In the case of a
series of transactions constituting a Change in Control, “Closing” means the first closing that satisfies the threshold of the definition for a Change in Control. 
 (h) “COBRA” means the Consolidated Omnibus Budget Reconciliation Act of 1985. 
 (i) “Code” means the Internal Revenue Code of 1986, as amended. 
 (j) “Company” means ACADIA Pharmaceuticals Inc. or, following a Change in Control, the surviving entity resulting from such event. 

(k) “Covered Period” means the period commencing 30 days prior to the Closing of a Change in Control and
ending 13 months following the Closing of a Change in Control. 
 (l) “Covered Termination” means
an Involuntary Termination that occurs within the Covered Period. For such purposes, if the events giving rise to an employee’s right to resign for Good Reason arise within the Covered Period, and the employee’s resignation occurs not
later than 30 days after the expiration of the Cure Period (as defined below), such termination shall be a Covered Termination. 

(m) “Director” means a member of the Board. 

(n) “Eligible Employee” means an employee of the Company that meets the requirements to be eligible to
receive Plan benefits as set forth in Section 2. 

  
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 (o) “Entity” means a corporation, partnership, limited
liability company or other entity. 
 (p) “Exchange Act” means the Securities Exchange Act of
1934, as amended, and the rules and regulations promulgated thereunder. 
 (q) “Exchange Act
Person” means any natural person, Entity or “group” (within the meaning of Section 13(d) or 14(d) of the Exchange Act), except that “Exchange Act Person” shall not include (i) the Company or any Subsidiary
of the Company, (ii) any employee benefit plan of the Company or any Subsidiary of the Company or any trustee or other fiduciary holding securities under an employee benefit plan of the Company or any Subsidiary of the Company, (iii) an
underwriter temporarily holding securities pursuant to a registered public offering of such securities, (iv) an Entity Owned, directly or indirectly, by the stockholders of the Company in substantially the same proportions as their Ownership of
stock of the Company; or (v) any natural person, Entity or “group” (within the meaning of Section 13(d) or 14(d) of the Exchange Act) that, as of the Effective Date, is the Owner, directly or indirectly, of securities of the
Company representing more than 50% of the combined voting power of the Company’s then outstanding securities. 
 (r)
“Good Reason” for an employee’s resignation means the occurrence of any of the following events, conditions or actions taken by the Company without Cause and without such employee’s consent: (i) the
assignment to employee of any duties or responsibilities that results in a material diminution in the employee’s authorities, duties or responsibilities as in effect immediately prior to such reduction; provided, however, that a change in the
employee’s title or reporting relationships shall not provide the basis for a termination with Good Reason; (ii) a material reduction by the Company in the employee’s annual base salary, as in effect prior to such reduction;
(iii) a relocation of the employee’s principal business office to a location that increases the employee’s one-way driving distance by 30 miles or more, except for required travel by the employee on the Company’s business
consistent with such employee’s business travel obligations as in effect on the Effective Date; or (iv) a material breach by the Company of any provision of the Plan or any other material agreement between the employee and the Company
concerning the terms and conditions of the employee’s employment; provided, however, that in each case above, in order for the employee’s resignation to be deemed to have been for Good Reason, the employee must first give the
Company written notice of the action or omission giving rise to “Good Reason” within 30 days after the first occurrence thereof; the Company must fail to reasonably cure such action or omission within 30 days after receipt of such notice
(the “Cure Period”), and the employee’s resignation must be effective not later than 30 days after the expiration of such Cure Period. 
 (s) “Involuntary Termination” means a termination of employment that is due to: (i) a termination by the Company without Cause or (ii) an employee’s
resignation for Good Reason. 
 (t) “Own,” “Owned,”
“Owner,” “Ownership” means a person or Entity shall be deemed to “Own,” to have “Owned,” to be the “Owner” of, or to have acquired “Ownership” of securities if
such person or Entity, directly or indirectly, through any contract, arrangement, understanding, relationship or otherwise, has or shares voting power, which includes the power to vote or to direct the voting, with respect to such securities.

 (u) “Participation Agreement” means an agreement between an employee and the Company in
substantially the form of Appendix A attached hereto, and which may include such other terms as the Board deems necessary or advisable in the administration of the Plan. 
 (v) “Plan Administrator” means the Board prior to the Closing and the Representative upon and following the Closing. 

  
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 (w) “Representative” means one or more members of the Board
or other persons or entities designated by the Board prior to or in connection with a Change in Control that will have authority to administer and interpret the Plan upon and following the Closing as provided in Section 7(a). 

(x) “Subsidiary” means, with respect to the Company, (i) any corporation of which more than 50% of
the outstanding capital stock having ordinary voting power to elect a majority of the board of directors of such corporation (irrespective of whether, at the time, stock of any other class or classes of such corporation shall have or might have
voting power by reason of the happening of any contingency) is at the time, directly or indirectly, Owned by the Company, and (ii) any partnership, limited liability company or other entity in which the Company has a direct or indirect interest
(whether in the form of voting or participation in profits or capital contribution) of more than 50%. 
 (y)
“Target Bonus” means with respect to an Eligible Employee, if there is a cash bonus plan applicable to such Eligible Employee for the year in which such Covered Termination occurs (“Cash Bonus
Plan”), the cash bonus payable to such Eligible Employee under such Cash Bonus Plan as if all the applicable performance goals were attained for such year were attained at a level of 100%. If no Cash Bonus Plan is in effect for the year
in which such Covered Termination occurs, the Target Bonus Amount will be $0. 
  

	Section 2.	ELIGIBILITY FOR BENEFITS. 

 (a) Eligible Employee. An employee of the Company is eligible to participate in the Plan if (i) the Board has designated such employee as eligible to participate in the Plan by providing such
person with a Participation Agreement; (ii) such employee has signed and returned such Participation Agreement to the Company within the period specified therein; (iii) such employee’s employment with the Company terminates due to a
Covered Termination; and (iv) such employee meets the other Plan eligibility requirements set forth in this Section 2. The determination of whether an employee is an Eligible Employee shall be made by the Plan Administrator, in its sole
discretion, and such determination shall be binding and conclusive on all persons. 
 (b) Release Requirement. In order
to be eligible to receive benefits under the Plan, the employee also must execute a general waiver and release in substantially the form attached hereto as Exhibit A, Exhibit B or Exhibit C, as appropriate (the “Release”),
within the applicable time period set forth therein, but in no event more than 50 days following the date of the applicable Covered Termination, and such Release must become effective in accordance with its terms. The Company, in its sole
discretion, may modify the form of the Release to comply with applicable law and shall determine the form of the required Release, which may be incorporated into a termination agreement or other agreement with the employee. 

(c) Plan Benefits Provided in Lieu of Individual Agreement Severance Benefits. Unless otherwise determined by the Plan
Administrator in its discretion, if an employee is an Eligible Employee and eligible to receive severance benefits under this Plan and otherwise eligible to receive severance benefits under the terms of an individually negotiated employment contract
or agreement with the Company or any other severance arrangement with the Company that are of the same category and would otherwise duplicate the severance benefits available under this Plan (“Duplicative Benefits”) such
Eligible Employee will receive severance benefits under this Plan in lieu of, and not additional to, such Duplicative Benefits. If an Eligible Employee is eligible to receive Plan benefits, such Eligible Employee will receive severance benefits
under any individually negotiated employment contract or agreement only to the extent that such benefits are not Duplicative Benefits. 
 (d) Exceptions to Benefit Entitlement. An employee who otherwise is an Eligible Employee will not receive benefits under the Plan in the following circumstances, as determined by the Plan
Administrator in its sole discretion: 
 (1) The employee voluntarily terminates employment with the Company without
Good Reason, or terminates employment due to the employee’s death or disability. Voluntary terminations include, but are not limited to, resignation, retirement, or failure to return from a leave of absence on the scheduled date. 

  
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 (2) The employee voluntarily terminates employment with the Company in order to
accept employment with another entity that is wholly or partly owned (directly or indirectly) by the Company or an Affiliate. 

(3) The employee is offered an identical or substantially equivalent or comparable position with the Company or an Affiliate. For
purposes of the foregoing, a “substantially equivalent or comparable position” is one that provides the employee substantially the same level of responsibility and compensation and would not give rise to the employee’s right to resign
for Good Reason. 
 (4) The employee is offered immediate reemployment by a successor to the Company or an Affiliate or
by a purchaser of the Company’s assets, as the case may be, following a Change in Control and the terms of such reemployment would not give rise to the employee’s right to resign for Good Reason. For purposes of the foregoing,
“immediate reemployment” means that the employee’s employment with the successor to the Company or an Affiliate or the purchaser of its assets, as the case may be, results in uninterrupted employment such that the employee does not
incur a lapse in pay or benefits as a result of the change in ownership of the Company or the sale of its assets. 
 (5)
The employee is rehired by the Company or an Affiliate and recommences employment prior to the date benefits under the Plan are scheduled to commence. 
  

	Section 3.	AMOUNT OF BENEFIT. 

 (a) Severance Benefit. Benefits under the Plan shall be provided to an Eligible Employee as set forth in the Participation Agreement. 

(b) Additional Benefits. Notwithstanding the foregoing, the Company may, in its sole discretion, provide benefits to employees who
are not Eligible Employees (“Non-Eligible Employees”) chosen by the Board, in its sole discretion, and the provision of any such benefits to a Non-Eligible Employee shall in no way obligate the Company to provide such
benefits to any other Non-Eligible Employee, even if similarly situated. If benefits under the Plan are provided to a Non-Eligible Employee, references in the Plan to “Eligible Employee” (and similar references) shall be deemed to refer to
such Non-Eligible Employee. 
 (c) Certain Reductions. The Company, in its sole discretion, shall have the authority to
reduce an Eligible Employee’s severance benefits, in whole or in part, by pay and benefits provided during a period following written notice of a plant closing or mass layoff, pay and benefits in lieu of such notice, or other similar benefits
payable to the Eligible Employee by the Company or an Affiliate that become payable in connection with the Eligible Employee’s termination of employment pursuant to (i) any applicable legal requirement, including, without limitation, the
Worker Adjustment and Retraining Notification Act or any other similar state law, or (ii) any Company policy or practice providing for the Eligible Employee to remain on the payroll for a limited period of time after being given notice of the
termination of the Eligible Employee’s employment, and the Plan Administrator shall so construe and implement the terms of the Plan. Any such reductions that the Company determines to make pursuant to this Section 3(c) shall be made such
that any benefit under the Plan shall be reduced solely by any similar type of benefit under such legal requirement, agreement, policy or practice (i.e., any cash severance benefits under the Plan shall be reduced solely by any cash payments
or severance benefits under such legal requirement, agreement, policy or practice, and any continued insurance benefits under the Plan shall be reduced solely by any continued insurance benefits under such legal requirement, agreement, policy or
practice). The Company’s decision to apply such reductions to the severance benefits of one Eligible Employee and the amount of such reductions shall in no way obligate the 

  
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Company to apply the same reductions in the same amounts to the severance benefits of any other Eligible Employee, even if similarly situated. In the Company’s sole discretion, such
reductions may be applied on a retroactive basis, with severance benefits previously paid being re-characterized as payments pursuant to the Company’s statutory obligation. 

(d) Parachute Payments. 
 (1) Any provision of the Plan to the contrary notwithstanding, if any payment or benefit an Eligible Employee would receive from the Company pursuant to the Plan or otherwise
(“Payment”) would (i) constitute a “parachute payment” within the meaning of Section 280G of the Code, and (ii) but for this sentence, be subject to the excise tax imposed by Section 4999 of the
Code (the “Excise Tax”), then such Payment will be equal to the Reduced Amount (defined below). The “Reduced Amount” shall be either (x) the largest portion of the Payment that would result in no
portion of the Payment being subject to the Excise Tax or (y) the largest portion, up to and including the total, of the Payment, whichever amount, after taking into account all applicable federal, state and local employment taxes, income
taxes, and the Excise Tax (all computed at the highest applicable marginal rate), results in the Eligible Employee’s receipt, on an after-tax basis, of the greater economic benefit notwithstanding that all or some portion of the Payment may be
subject to the Excise Tax. If a reduction in payments or benefits constituting “parachute payments” is necessary so that the Payment equals the Reduced Amount, reduction shall occur in the manner that results in the greatest economic
benefit for the Eligible Employee. If more than one method of reduction will result in the same economic benefit, the items so reduced will be reduced pro rata. 
 (2) In the event it is subsequently determined by the Internal Revenue Service that some portion of the Reduced Amount as determined pursuant to clause (x) in the preceding paragraph is
subject to the Excise Tax, the Eligible Employee agrees to promptly return to the Company a sufficient amount of the Payment so that no portion of the Reduced Amount is subject to the Excise Tax. For the avoidance of doubt, if the Reduced Amount is
determined pursuant to clause (y) in the preceding paragraph, the Eligible Employee will have no obligation to return any portion of the Payment pursuant to the preceding sentence. 

(3) Unless the Eligible Employee and the Company agree on an alternative accounting firm or law firm, the accounting firm engaged
by the Company for general tax compliance purposes as of the day prior to the effective date of the Change in Control shall perform the foregoing calculations. If the accounting firm so engaged by the Company is serving as accountant or auditor for
the individual, entity or group effecting the Change in Control, the Company shall appoint a nationally recognized accounting or law firm to make the determinations required hereunder. The Company shall bear all expenses with respect to the
determinations by such accounting or law firm required to be made hereunder. 
  

	Section 4.	RETURN OF COMPANY PROPERTY. 

An Eligible Employee will not be entitled to any severance benefit under the Plan unless and until the Eligible Employee returns all
Company Property. For this purpose, “Company Property” means all Company documents (and all copies thereof) and other Company property which the Eligible Employee had in his or her possession at any time, including, but not limited to,
Company files, notes, drawings, records, plans, forecasts, reports, studies, analyses, proposals, agreements, financial information, research and development information, sales and marketing information, operational and personnel information,
specifications, code, software, databases, computer-recorded information, tangible property and equipment (including, but not limited to, computers, facsimile machines, mobile telephones, servers), credit cards, entry cards, identification badges
and keys; and any materials of any kind which contain or embody any proprietary or confidential information of the Company (and all reproductions thereof in whole or in part). 

  
 7 

	Section 5.	TIME OF PAYMENT AND FORM OF BENEFIT.

 The Company reserves the right in the Participation Agreement to specify whether severance payments under
the Plan will be paid in a single sum, in installments, or in any other form and to determine the timing of such payments. All such payments under the Plan will be subject to applicable withholding for federal, state, and local taxes. If an Eligible
Employee is indebted to the Company on his or her termination date, the Company reserves the right to offset any severance payments under the Plan by the amount of such indebtedness. All severance benefits provided under the Plan are intended to
satisfy the requirements for an exemption from application of Section 409A of the Code to the maximum extent that an exemption is available and any ambiguities herein shall be interpreted accordingly. 

Notwithstanding anything to the contrary set forth herein, any payments and benefits provided under the Plan that constitute
“deferred compensation” within the meaning of Section 409A of the Code and the regulations and other guidance thereunder and any state law of similar effect (collectively “Section 409A”) shall not commence in
connection with an Eligible Employee’s termination of employment unless and until the Eligible Employee has also incurred a “separation from service,” as such term is defined in Treasury Regulations Section 1.409A-1(h)
(“Separation from Service”), unless the Company reasonably determines that such amounts may be provided to the Eligible Employee without causing the Eligible Employee to incur the adverse personal tax consequences under
Section 409A. 
 It is intended that (i) each installment of any benefits payable under the Plan to an Eligible
Employee be regarded as a separate “payment” for purposes of Treasury Regulations Section 1.409A-2(b)(2)(i), (ii) all payments of any such benefits under the Plan satisfy, to the greatest extent possible, the exemptions from the
application of Section 409A provided under Treasury Regulations Sections 1.409A-1(b)(4) and 1.409A-1(b)(9)(iii), and (iii) any such benefits consisting of COBRA premiums also satisfy, to the greatest extent possible, the exemption from the
application of Section 409A provided under Treasury Regulations Section 1.409A-1(b)(9)(v). However, if the Company determines that any such benefits payable under the Plan constitute “deferred compensation” under
Section 409A and the Eligible Employee is a “specified employee” of the Company, as such term is defined in Section 409A(a)(2)(B)(i), then, solely to the extent necessary to avoid the imposition of the adverse personal tax
consequences under Section 409A, (i) the timing of such benefit payments shall be delayed until the earlier of (A) the date that is 6 months and 1 day after the Eligible Employee’s Separation from Service and (B) the date of
the Eligible Employee’s death (such applicable date, the “Delayed Initial Payment Date”), and (ii) the Company shall (A) pay the Eligible Employee a lump sum amount equal to the sum of the benefit payments that
the Eligible Employee would otherwise have received through the Delayed Initial Payment Date if the commencement of the payment of the benefits had not been delayed pursuant to this paragraph and (B) commence paying the balance, if any, of the
benefits in accordance with the applicable payment schedule. 
 In no event shall payment of any benefits under the Plan be made
prior to an Eligible Employee’s termination date or prior to the effective date of the Release. If the Company determines that any payments or benefits provided under the Plan constitute “deferred compensation” under
Section 409A, and the Eligible Employee’s Separation from Service occurs at a time during the calendar year when the Release could become effective in the calendar year following the calendar year in which the Eligible Employee’s
Separation from Service occurs, then regardless of when the Release is returned to the Company and becomes effective, the Release will not be deemed effective any earlier than the latest permitted effective date (the “Release
Deadline”). If the Company determines that any payments or 

  
 8 

 
benefits provided under the Plan constitute “deferred compensation” under Section 409A, then except to the extent that payments may be delayed until the Delayed Initial Payment
Date pursuant to the preceding paragraph, on the first regular payroll date following the effective date of an Eligible Employee’s Release, the Company shall (i) pay the Eligible Employee a lump sum amount equal to the sum of the benefit
payments that the Eligible Employee would otherwise have received through such payroll date but for the delay in payment related to the effectiveness of the Release and (ii) commence paying the balance, if any, of the benefits in accordance
with the applicable payment schedule. 
  

	Section 6.	REEMPLOYMENT. 

 In the event of an Eligible Employee’s reemployment by the Company during the period of time in respect of which severance benefits pursuant to the Plan have been paid, the Company, in its sole and
absolute discretion, may require such Eligible Employee to repay to the Company all or a portion of such severance benefits as a condition of reemployment. 
  

	Section 7.	RIGHT TO INTERPRET AND ADMINISTER PLAN; AMENDMENT
AND TERMINATION. 

 (a) Interpretation and Administration. Prior to the
Closing, the Board shall be the Plan Administrator and shall have the exclusive discretion and authority to establish rules, forms, and procedures for the administration of the Plan and to construe and interpret the Plan and to decide any and all
questions of fact, interpretation, definition, computation or administration arising in connection with the operation of the Plan, including, but not limited to, the eligibility to participate in the Plan and amount of benefits paid under the Plan.
The rules, interpretations, computations and other actions of the Board shall be binding and conclusive on all persons. Upon and after the Closing, the Plan will be interpreted and administered in good faith by the Representative who shall be the
Plan Administrator during such period. All actions taken by the Representative in interpreting the terms of the Plan and administering the Plan upon and after the Closing will be final and binding on all Eligible Employees. Any references in this
Plan to the “Board” or “Plan Administrator” with respect to periods following the Closing shall mean the Representative. 
 (b) Amendment. The Plan Administrator reserves the right to amend this Plan at any time; provided, however, that any amendment of the Plan will not be effective as to a particular employee
who is or may be adversely impacted by such amendment or termination and has an effective Participation Agreement without the written consent of such employee. Any action amending the Plan shall be in writing and executed by the Company’s
Chairman of the Board (prior to the Closing) or the Representative (following the Closing). 
 (c) Termination. The Plan
will automatically terminate upon the earliest of: (i) the date 5 years after the Effective Date, if the Closing has not occurred on or prior to such date, or (ii) following satisfaction of all the Company’s obligations under the
Plan. 
  

	Section 8.	NO IMPLIED EMPLOYMENT CONTRACT. 

The Plan shall not be deemed (i) to give any employee or other person any right to be retained in the employ of the Company or
(ii) to interfere with the right of the Company to discharge any employee or other person at any time, with or without cause, which right is hereby reserved. 

  
 9 

	Section 9.	LEGAL CONSTRUCTION. 

 This Plan is intended to be governed by and shall be construed in accordance with the Employee Retirement Income Security Act of 1974 (“ERISA”) and, to the extent not preempted by
ERISA, the laws of the State of California. 
  

	Section 10.	CLAIMS, INQUIRIES AND APPEALS. 

(a) Applications for Benefits and Inquiries. Any application for benefits, inquiries about the Plan or inquiries about present or
future rights under the Plan must be submitted to the Plan Administrator in writing by an applicant (or his or her authorized representative). The Plan Administrator is: 
 ACADIA Pharmaceuticals Inc. 
 Board of Directors 

3911 Sorrento Valley Blvd. 
 San Diego, CA 92121 
 (b) Denial of Claims. In the event that any
application for benefits is denied in whole or in part, the Plan Administrator must provide the applicant with written or electronic notice of the denial of the application, and of the applicant’s right to review the denial. Any electronic
notice will comply with the regulations of the U.S. Department of Labor. The notice of denial will be set forth in a manner designed to be understood by the applicant and will include the following: 

(1) the specific reason or reasons for the denial; 
 (2) references to the specific Plan provisions upon which the denial is based; 
 (3) a description of any additional information or material that the Plan Administrator needs to complete the review and an explanation of why such information or material is necessary; and

 (4) an explanation of the Plan’s review procedures and the time limits applicable to such procedures, including
a statement of the applicant’s right to bring a civil action under Section 502(a) of ERISA following a denial on review of the claim, as described in Section 10(d) below. 

This notice of denial will be given to the applicant within 90 days after the Plan Administrator receives the application, unless special
circumstances require an extension of time, in which case, the Plan Administrator has up to an additional 90 days for processing the application. If an extension of time for processing is required, written notice of the extension will be furnished
to the applicant before the end of the initial 90 day period. 
 This notice of extension will describe the special
circumstances necessitating the additional time and the date by which the Plan Administrator is to render its decision on the application. 
 (c) Request for a Review. Any person (or that person’s authorized representative) for whom an application for benefits is denied, in whole or in part, may appeal the denial by submitting a
request for a review to the Plan Administrator within 60 days after the application is denied. A request for a review shall be in writing and shall be addressed to: 

  
 10 

 ACADIA Pharmaceuticals Inc. 

Board of Directors 

3911 Sorrento Valley Blvd. 
 San Diego, CA 92121 
 A request for review must set forth all of the grounds on which it is based,
all facts in support of the request and any other matters that the applicant feels are pertinent. The applicant (or his or her representative) shall have the opportunity to submit (or the Plan Administrator may require the applicant to submit)
written comments, documents, records, and other information relating to his or her claim. The applicant (or his or her representative) shall be provided, upon request and free of charge, reasonable access to, and copies of, all documents, records
and other information relevant to his or her claim. The review shall take into account all comments, documents, records and other information submitted by the applicant (or his or her representative) relating to the claim, without regard to whether
such information was submitted or considered in the initial benefit determination. 
 (d) Decision on Review. The Plan
Administrator will act on each request for review within 60 days after receipt of the request, unless special circumstances require an extension of time (not to exceed an additional 60 days), for processing the request for a review. If an extension
for review is required, written notice of the extension will be furnished to the applicant within the initial 60 day period. This notice of extension will describe the special circumstances necessitating the additional time and the date by which the
Plan Administrator is to render its decision on the review. The Plan Administrator will give prompt, written or electronic notice of its decision to the applicant. Any electronic notice will comply with the regulations of the U.S. Department of
Labor. In the event that the Plan Administrator confirms the denial of the application for benefits in whole or in part, the notice will set forth, in a manner calculated to be understood by the applicant, the following: 

(1) the specific reason or reasons for the denial; 
 (2) references to the specific Plan provisions upon which the denial is based; 
 (3) a statement that the applicant is entitled to receive, upon request and free of charge, reasonable access to, and copies of, all documents, records and other information relevant to his or her
claim; and 
 (4) a statement of the applicant’s right to bring a civil action under Section 502(a) of ERISA.

 (e) Rules and Procedures. The Plan Administrator will establish rules and procedures, consistent with the Plan and
with ERISA, as necessary and appropriate in carrying out its responsibilities in reviewing benefit claims. The Plan Administrator may require an applicant who wishes to submit additional information in connection with an appeal from the denial of
benefits to do so at the applicant’s own expense. 
 (f) Exhaustion of Remedies. No legal action for benefits under
the Plan may be brought until the applicant (i) has submitted a written application for benefits in accordance with the procedures described by Section 10(a) above, (ii) has been notified by the Plan Administrator that the application
is denied, (iii) has filed a written request for a review of the application in accordance with the appeal procedure described in Section 10(c) above, and (iv) has been notified that the Plan Administrator has denied the appeal.
Notwithstanding the foregoing, if the Plan Administrator does not respond to an Eligible Employee’s claim or appeal within the relevant time limits specified in this Section 10, the Eligible Employee may bring legal action for benefits
under the Plan pursuant to Section 502(a) of ERISA. 

  
 11 

	Section 11.	BASIS OF PAYMENTS TO AND FROM PLAN.

 The Plan shall be unfunded, and all cash payments under the Plan shall be paid only from the general assets
of the Company. 
  

	Section 12.	OTHER PLAN INFORMATION. 

 (a) Employer and Plan Identification Numbers. The Employer Identification Number assigned to the Company (which is the “Plan Sponsor” as that term is used in ERISA) by the Internal
Revenue Service is 06-1376651. The Plan Number assigned to the Plan by the Plan Sponsor pursuant to the instructions of the Internal Revenue Service is 510. 
 (b) Ending Date for Plan’s Fiscal Year. The date of the end of the fiscal year for the purpose of maintaining the Plan’s records is December 31. 

(c) Agent for the Service of Legal Process. The agent for the service of legal process with respect to the Plan is: 

ACADIA Pharmaceuticals Inc. 
 3911 Sorrento Valley Blvd. 
 San Diego, CA 92121 

In addition, service of legal process may be made upon the Plan Administrator. 
 (d) Plan Sponsor. The “Plan Sponsor” is: 
 ACADIA Pharmaceuticals
Inc. 
 3911 Sorrento Valley Blvd. 
 San Diego, CA 92121 
 (858) 558-2871 

(e) Plan Administrator. The Plan Administrator is the Board prior to the Closing and the Representative upon and following the
Closing. The Plan Administrator’s contact information is: 
 ACADIA Pharmaceuticals Inc. 

Board of Directors or Representative 
 3911 Sorrento Valley Blvd. 
 San Diego, CA 92121 

(858) 558-2871 
 The Plan Administrator is the named fiduciary charged with the responsibility for administering the Plan. 
  

	Section 13.	STATEMENT OF ERISA RIGHTS. 

 Participants in this Plan (which is a welfare benefit plan sponsored by ACADIA Pharmaceuticals Inc.) are entitled to certain rights and protections under ERISA. If you are an Eligible Employee, you are
considered a participant in the Plan and, under ERISA, you are entitled to: 
 (a) Receive Information About Your Plan and
Benefits 

  
 12 

 (1) Examine, without charge, at the Plan Administrator’s office and at other
specified locations, such as worksites, all documents governing the Plan and a copy of the latest annual report (Form 5500 Series), if applicable, filed by the Plan with the U.S. Department of Labor and available at the Public Disclosure Room of the
Employee Benefits Security Administration; 
 (2) Obtain, upon written request to the Plan Administrator, copies of
documents governing the operation of the Plan and copies of the latest annual report (Form 5500 Series), if applicable, and an updated (as necessary) Summary Plan Description. The Administrator may make a reasonable charge for the copies; and

 (3) Receive a summary of the Plan’s annual financial report, if applicable. The Plan Administrator is required
by law to furnish each Eligible Employee with a copy of this summary annual report. 
 (b) Prudent Actions by Plan
Fiduciaries. In addition to creating rights for Plan Eligible Employees, ERISA imposes duties upon the people who are responsible for the operation of the employee benefit plan. The people who operate the Plan, called “fiduciaries” of
the Plan, have a duty to do so prudently and in the interest of you and other Eligible Employees and beneficiaries. No one, including your employer, your union or any other person, may fire you or otherwise discriminate against you in any way to
prevent you from obtaining a Plan benefit or exercising your rights under ERISA. 
 (c) Enforce Your Rights. If your
claim for a Plan benefit is denied or ignored, in whole or in part, you have a right to know why this was done, to obtain copies of documents relating to the decision without charge, and to appeal any denial, all within certain time schedules.

 Under ERISA, there are steps you can take to enforce the above rights. For instance, if you request a copy of Plan documents
or the latest annual report from the Plan, if applicable, and do not receive them within 30 days, you may file suit in a Federal court. In such a case, the court may require the Plan Administrator to provide the materials and pay you up to $110 a
day until you receive the materials, unless the materials were not sent because of reasons beyond the control of the Plan Administrator. 
 If you have a claim for benefits which is denied or ignored, in whole or in part, you may file suit in a state or Federal court. 
 If you are discriminated against for asserting your rights, you may seek assistance from the U.S. Department of Labor, or you may file suit in a Federal court. The court will decide who should pay court
costs and legal fees. If you are successful, the court may order the person you have sued to pay these costs and fees. If you lose, the court may order you to pay these costs and fees, for example, if it finds your claim is frivolous. 

(d) Assistance with Your Questions. If you have any questions about the Plan, you should contact the Plan Administrator. If you
have any questions about this statement or about your rights under ERISA, or if you need assistance in obtaining documents from the Plan Administrator, you should contact the nearest office of the Employee Benefits Security Administration, U.S.
Department of Labor, listed in your telephone directory or the Division of Technical Assistance and Inquiries, Employee Benefits Security Administration, U.S. Department of Labor, 200 Constitution Avenue N.W., Washington, D.C. 20210. You may also
obtain certain publications about your rights and responsibilities under ERISA by calling the publications hotline of the Employee Benefits Security Administration. 

  
 13 

 APPENDIX A 

ACADIA PHARMACEUTICALS INC. 
 CHANGE IN CONTROL SEVERANCE BENEFIT PLAN 

PARTICIPATION AGREEMENT 
 Name: 
                                        

  

	Section 1.	ELIGIBILITY. 

 You have been designated as eligible to participate in the ACADIA Pharmaceuticals Inc. Change in Control Severance Benefit Plan (the “Plan”), a copy of which is attached as
EXHIBIT A to this Participation Agreement (the “Agreement”). Capitalized terms not explicitly defined in this Agreement but defined in the Plan shall have the same definitions as in the Plan. 

 

	Section 2.	SEVERANCE BENEFITS 

 Subject to the terms of the Plan, if you are terminated in a Covered Termination, and meet all the other eligibility requirements set forth in the Plan, including, without limitation, executing the
required Release within the applicable time period set forth therein and provided that such Release becomes effective in accordance with its terms, you will receive the severance benefits set forth in this Section 2. Notwithstanding the
schedule for provision of severance benefits as set forth below, the provision of any severance benefits under this Section 2 is subject to any delay in payment that may be required under Section 5 of the Plan. 

(a) Base Compensation Severance Benefit. You will be entitled to receive a single lump sum cash payment equal
to ( (        %)1 of the sum of your Annual Base Salary plus Average Annual Bonus (the “Base Compensation Severance Benefit”). The Base Compensation Severance Benefit will be payable to you within 10
business days following the later of (i) the effective date of your Release, or (ii) the effective date of the Closing. 

(b) Target Bonus Severance Benefit. You will be entitled to receive a single lump sum cash payment equal to a pro-rata
portion of your Target Bonus, with such pro-rata portion calculated with reference to the number of days in the calendar year that precedes the date of the Covered Termination divided by the number of days in the calendar year that includes the date
of the Covered Termination (the “Target Bonus Severance Benefit”). The Target Bonus Severance Benefit will be payable to you within 10 business days following the later of (i) the effective date of your Release, or (ii) the
effective date of the Closing. 
 (c) Accelerated Vesting of Stock Awards. 

(1) Effective as of the later of the effective date of your Release or the effective date of the Closing, to the extent not
previously vested: (i) the vesting and exercisability of all outstanding stock options to purchase the Company’s common stock that are held by you on such date shall be accelerated in full, (ii) any reacquisition or repurchase rights
held by the Company in respect of common stock issued pursuant to any other stock award granted to you by the Company shall lapse in full, and (iii) the vesting of any other stock awards granted to you by the Company, and any issuance of

  
  

	1 	Base Compensation Severance Benefits for named executive officers to be provided as follows: 

			
	 Name and Position
	  	 % of Annual Base Salary plus Average
Annual Bonus

	 Uli Hacksell, CEO & President
	  	1.5%
	 Thomas H. Aasen, EVP, CFO & CBO
	  	1.3%
	 Roger M. Mills, EVP, Development & CMO
	  	1.3%
	 Glenn F. Baity, VP & GC
	  	1.15%

  
 14 

 
shares triggered by the vesting of such stock awards, shall be accelerated in full. Notwithstanding the foregoing, this Section 2(c) shall not apply to stock awards issued under or held in
any Qualified Plan. For purposes of determining the number of shares that will vest pursuant to the foregoing provision with respect to any performance based vesting award that has multiple vesting levels depending upon the level of performance,
vesting acceleration shall occur with respect to the number of shares subject to the award as if the applicable performance criteria had been attained at a 100% level. 
 (2) In order to give effect to the intent of the foregoing provision, notwithstanding anything to the contrary set forth in your stock award agreements or the applicable equity incentive plan under
which such stock award was granted that provides that any then unvested portion of your award will immediately expire upon your termination of service, no unvested portion of your stock award shall terminate any earlier than 30 days following any
Involuntary Termination of your employment that occurs prior to a Closing. Notwithstanding anything to the contrary set forth herein, your stock awards shall remain subject to earlier termination in connection with a “Corporate
Transaction” as provided in the Equity Plan or substantially equivalent provisions applicable to your stock award. 

(d) Payment of Continued Group Health Plan Benefits. 

(1) If you timely elect continued group health plan continuation coverage under COBRA the Company shall pay
the full amount of your COBRA premiums, or shall provide coverage under any self-funded plan, on behalf of you for your continued coverage under the Company’s group health plans, including coverage for your eligible dependents, for
[            
(    )]2 months
following your Covered Termination (the “COBRA Payment Period”). Upon the conclusion of such period of insurance premium payments made by the Company, or the provision of coverage under a self-funded group health plan, you
will be responsible for the entire payment of premiums (or payment for the cost of coverage) required under COBRA for the duration of your eligible COBRA coverage period. For purposes of this Section, (i) references to COBRA shall be deemed to refer
also to analogous provisions of state law and (ii) any applicable insurance premiums that are paid by the Company shall not include any amounts payable by you under an Internal Revenue Code Section 125 health care reimbursement plan, which amounts,
if any, are your sole responsibility. 
 (2) Notwithstanding the foregoing, if at any time the Company determines, in
its sole discretion, that it cannot provide the COBRA premium benefits without potentially incurring financial costs or penalties under applicable law (including, without limitation, Section 2716 of the Public Health Service Act), then in lieu
of paying COBRA premiums on the your behalf, the Company will instead pay you on the last day of each remaining month of the COBRA Payment Period a fully taxable cash payment equal to the COBRA premium for that month, subject to applicable tax
withholding (such amount, the “Special Severance Payment”), such Special Severance Payment to be made without regard to yours election of COBRA coverage or payment of COBRA premiums and without regard to your continued
eligibility for COBRA coverage during the COBRA Payment Period. Such Special Severance Payment shall end upon expiration of the COBRA Payment Period. 
 (e) Outplacement Benefits. You will receive outplacement services of up to $             through an agency selected by the
Company.3 

 
  

	2 	 COBRA Payment Periods for named executive officers are as follows: 

			
	 Name and Position
	  	 COBRA Payment Period

	 Uli Hacksell, CEO & President
	  	18 Months
	 Thomas H. Aasen, EVP, CFO & CBO
	  	16 Months
	 Roger M. Mills, EVP, Development & CMO
	  	16 Months
	 Glenn F. Baity, VP & GC
	  	14 Months
	
	 3    Outplacement benefits for named executive officers are as follows:

	 Name and Position
	  	 Amount

	 Uli Hacksell, CEO & President
	  	$18,000
	 Thomas H. Aasen, EVP, CFO & CBO
	  	$15,600
	 Roger M. Mills, EVP, Development & CMO
	  	$15,600
	 Glenn F. Baity, VP & GC
	  	$13,800

  
 15 

	Section 3.	DEFINITIONS. 

 (a) “Equity Plan” means the Company’s 1997 Stock Option Plan, 2004 Equity Incentive Plan, 2010 Equity Incentive Plan or any successor or other equity incentive plan
adopted by the Company which govern your stock awards, as applicable. 
 (b) “Qualified Plan”
means a plan sponsored by the Company or an Affiliate that is intended to be qualified under Section 401(a) of the Internal Revenue Code. 
  

	Section 4.	ACKNOWLEDGEMENTS. 

 As a condition to participation in the Plan, you hereby acknowledge each of the following: 
 (a) The severance benefits that may be provided to you under this Agreement are subject to certain reductions under Section 3 of the Plan. 

(b) This Agreement and the Plan supersedes any severance benefit plan, policy or practice previously maintained by the Company
that may have been applicable to you. Notwithstanding the foregoing, this Agreement and the Plan do not supersede your individually negotiated employment agreement with the Company dated
                        , as it may be amended thereafter from time to time (as so amended, the “Employment
Agreement”). 
 (c) The severance benefits that may be provided to you under this Agreement may reduce the
severance benefits that would otherwise be provided to you under your Employment Agreement as further specified in Section 2(c) of the Plan. 
 To accept the terms of this Agreement and participate in the Plan, please sign and date this Agreement in the space provided below and return it to
                         no later than
                , 2013. 
 ACADIA Pharmaceuticals Inc.

  

							
	
By:                       
                                         
                                         
                
	 		 	
	  

Title:                
                                         
                                         
                   
	 		 	
		 		 	
		 		 	
		 		 	
	  

[Eligible Employee]
	 		 	  
 Date

  
 16 

 For Eligible Employees Age 40 or Older 

Individual Termination 
 EXHIBIT A 
 RELEASE AGREEMENT 

I understand and agree completely to the terms set forth in the ACADIA Pharmaceuticals Inc. Change in Control Severance Benefit Plan
(the “Plan”). 
 I understand that this Release Agreement (the
“Release”), together with the Plan, constitutes the complete, final and exclusive embodiment of the entire agreement between the Company, affiliates of the Company and me with regard to the subject matter hereof. I am not
relying on any promise or representation by the Company or an affiliate of the Company that is not expressly stated therein. Certain capitalized terms used in this Release are defined in the Plan. 

I hereby confirm my obligations under my proprietary information and inventions agreement with the Company and/or an affiliate of the
Company. 
 In consideration of the severance benefits and other consideration provided to me under the Plan that I am not
otherwise entitled to receive, I hereby generally and completely release the Company and its affiliates, and their parents, subsidiaries, successors, predecessors and affiliates, and their current and former partners, members, directors, officers,
employees, stockholders, shareholders, agents, attorneys, predecessors, successors, insurers, affiliates and assigns, from any and all claims, liabilities and obligations, both known and unknown, that arise out of or are in any way related to
events, acts, conduct, or omissions occurring at any time prior to and including the date I sign this Release (collectively, the “Released Claims”). The Released Claims include, but are not limited to: (a) all claims arising out of or
in any way related to my employment with the Company and its affiliates, or their affiliates, or the termination of that employment; (b) all claims related to my compensation or benefits, including salary, bonuses, commissions, vacation pay,
expense reimbursements, severance pay, fringe benefits, stock, stock options, or any other ownership, equity, or profits interests in the Company and its affiliates, or their affiliates; (c) all claims for breach of contract, wrongful
termination, and breach of the implied covenant of good faith and fair dealing; (d) all tort claims, including claims for fraud, defamation, emotional distress, and discharge in violation of public policy; and (e) all federal, state, and
local statutory claims, including claims for discrimination, harassment, retaliation, attorneys’ fees, or other claims arising under the federal Civil Rights Act of 1964 (as amended), the federal Americans with Disabilities Act of 1990 (as
amended), the federal Age Discrimination in Employment Act (as amended) (“ADEA”), and the federal Employee Retirement Income Security Act of 1974 (as amended). 

Notwithstanding the foregoing, I understand that the following rights or claims are not included in the Released Claims: (a) any
rights or claims for indemnification I may have pursuant to any written indemnification agreement with the Company or its affiliate to which I am a party; the charter, bylaws, or operating agreements of the Company or its affiliate; or under
applicable law; or (b) any rights that cannot be waived as a matter of law. In addition, I understand that nothing in this Release prevents me from filing, cooperating with, or participating in any proceeding before the Equal Employment
Opportunity Commission, the Department of Labor, or any other government agency, except that I hereby waive my right to any monetary benefits in connection with any such claim, charge or proceeding. I hereby represent and warrant that, other than
the claims identified in this paragraph, I am not aware of any claims I have or might have that are not included in the Released Claims. 
 I acknowledge that I am knowingly and voluntarily waiving and releasing any rights I may have under the ADEA, and that the consideration given under the Plan for the waiver and release in this paragraph
is in addition to anything of value to which I was already entitled. I further acknowledge that I 

  
 1 

 
have been advised by this writing, as required by the ADEA, that: (a) my waiver and release do not apply to any rights or claims that may arise after the date I sign this Release; (b) I
should consult with an attorney prior to signing this Release (although I may choose voluntarily not do so); (c) I have twenty-one (21) days to consider this Release (although I may choose voluntarily to sign this Release earlier);
(d) I have seven (7) days following the date I sign this Release to revoke the Release by providing written notice to an officer of the Company; and (e) this Release shall not be effective until the date upon which the revocation
period has expired, which shall be the eighth day after I sign this Release provided I have not revoked it. 
 I hereby
represent that I have been paid all compensation owed and for all hours worked; I have received all the leave and leave benefits and protections for which I am eligible pursuant to the Family and Medical Leave Act or otherwise; and I have not
suffered any on-the-job injury for which I have not already filed a workers’ compensation claim. 
 I acknowledge that to
become effective, I must sign and return this Release to the Company so that it is received not later than twenty-one (21) days following the date it is provided to me or such other date as specified by the Company. 

 

	
	ELIGIBLE EMPLOYEE
	
	
Printed Name:                     
                                         
    

	
	
Signature:                      
                                         
          

	
	
Date:                       
                                         
                 

  
 2 

 For Eligible Employees Age 40 or Older 

Group Termination 

EXHIBIT B 
 RELEASE AGREEMENT 
 I understand and agree completely to the terms set
forth in the ACADIA Pharmaceuticals Inc. Change in Control Severance Benefit Plan (the “Plan”). 
 I understand that this Release Agreement (the “Release”), together with the Plan, constitutes the complete, final and exclusive embodiment of the entire agreement between the
Company, affiliates of the Company and me with regard to the subject matter hereof. I am not relying on any promise or representation by the Company or an affiliate of the Company that is not expressly stated therein. Certain capitalized terms used
in this Release are defined in the Plan. 
 I hereby confirm my obligations under my proprietary information and inventions
agreement with the Company and/or an affiliate of the Company. 
 In consideration of the severance benefits and other
consideration provided to me under the Plan that I am not otherwise entitled to receive, I hereby generally and completely release the Company and its affiliates, and their parents, subsidiaries, successors, predecessors and affiliates, and its and
their current and former partners, members, directors, officers, employees, stockholders, shareholders, agents, attorneys, predecessors, successors, insurers, affiliates and assigns, from any and all claims, liabilities and obligations, both known
and unknown, that arise out of or are in any way related to events, acts, conduct, or omissions occurring at any time prior to and including the date I sign this Release (collectively, the “Released Claims”). The Released Claims include,
but are not limited to: (a) all claims arising out of or in any way related to my employment with the Company and its affiliates, or their affiliates, or the termination of that employment; (b) all claims related to my compensation or
benefits, including salary, bonuses, commissions, vacation pay, expense reimbursements, severance pay, fringe benefits, stock, stock options, or any other ownership, equity, or profits interests in the Company and its affiliates, or their
affiliates; (c) all claims for breach of contract, wrongful termination, and breach of the implied covenant of good faith and fair dealing; (d) all tort claims, including claims for fraud, defamation, emotional distress, and discharge in
violation of public policy; and (e) all federal, state, and local statutory claims, including claims for discrimination, harassment, retaliation, attorneys’ fees, or other claims arising under the federal Civil Rights Act of 1964 (as
amended), the federal Americans with Disabilities Act of 1990 (as amended), the federal Age Discrimination in Employment Act (as amended) (“ADEA”), and the federal Employee Retirement Income Security Act of 1974 (as amended).

 Notwithstanding the foregoing, I understand that the following rights or claims are not included in the Released Claims:
(a) any rights or claims for indemnification I may have pursuant to any written indemnification agreement with the Company or its affiliate to which I am a party; the charter, bylaws, or operating agreements of the Company or its affiliate; or
under applicable law; or (b) any rights that cannot be waived as a matter of law. In addition, I understand that nothing in this Release prevents me from filing, cooperating with, or participating in any proceeding before the Equal Employment
Opportunity Commission, the Department of Labor, or any other government agency, except that I hereby waive my right to any monetary benefits in connection with any such claim, charge or proceeding. I hereby represent and warrant that, other than
the claims identified in this paragraph, I am not aware of any claims I have or might have that are not included in the Released Claims. 
 I acknowledge that I am knowingly and voluntarily waiving and releasing any rights I may have under the ADEA, and that the consideration given under the Plan for the waiver and release in this paragraph
is in addition to anything of value to which I was already entitled. I further acknowledge that I 

 
have been advised by this writing, as required by the ADEA, that: (a) my waiver and release do not apply to any rights or claims that may arise after the date I sign this Release; (b) I
should consult with an attorney prior to signing this Release (although I may choose voluntarily not to do so); (c) I have forty-five (45) days to consider this Release (although I may choose voluntarily to sign this Release earlier);
(d) I have seven (7) days following the date I sign this Release to revoke the Release by providing written notice to an office of the Company; (e) this Release shall not be effective until the date upon which the revocation period
has expired, which shall be the eighth day after I sign this Release provided I have not revoked it; and (f) I have received with this Release all of the information required by the ADEA, including without limitation a detailed list of the job
titles and ages of all employees who were terminated in this group termination and the ages of all employees of the Company in the same job classification or organizational unit who were not terminated. 

I hereby represent that I have been paid all compensation owed and for all hours worked; I have received all the leave and leave benefits
and protections for which I am eligible pursuant to the Family and Medical Leave Act or otherwise; and I have not suffered any on-the-job injury for which I have not already filed a workers’ compensation claim. 

I acknowledge that to become effective, I must sign and return this Release to the Company so that it is received not later than
forty-five (45) days following the date it is provided to me or such other date as specified by the Company. 
  

	
	ELIGIBLE EMPLOYEE
	
	
Printed Name:                     
                                         
    

	
	
Signature:                      
                                         
          

	
	
Date:                       
                                         
                 

  
 2 

 For Eligible Employees Under Age 40 

Individual or Group Termination 
 EXHIBIT C 
 RELEASE AGREEMENT 

I understand and agree completely to the terms set forth in the ACADIA Pharmaceuticals Inc. Change in Control Severance Benefit Plan
(the “Plan”). 
 I understand that this Release Agreement (the “Release”),
together with the Plan, constitutes the complete, final and exclusive embodiment of the entire agreement between the Company, affiliates of the Company and me with regard to the subject matter hereof. I am not relying on any promise or
representation by the Company or an affiliate of the Company that is not expressly stated therein. Certain capitalized terms used in this Release are defined in the Plan. 
 I hereby confirm my obligations under my proprietary information and inventions agreement with the Company and/or an affiliate of the Company. 

In consideration of the severance benefits and other consideration provided to me under the Plan that I am not otherwise entitled to
receive, I hereby generally and completely release the Company and its affiliates, and their parents, subsidiaries, successors, predecessors and affiliates, and its and their current and former partners, members, directors, officers, employees,
stockholders, shareholders, agents, attorneys, predecessors, successors, insurers, affiliates and assigns, from any and all claims, liabilities and obligations, both known and unknown, that arise out of or are in any way related to events, acts,
conduct, or omissions occurring at any time prior to and including the date I sign this Release (collectively, the “Released Claims”). The Released Claims include, but are not limited to: (a) all claims arising out of or in any way
related to my employment with the Company and its affiliates, or their affiliates, or the termination of that employment; (b) all claims related to my compensation or benefits, including salary, bonuses, commissions, vacation pay, expense
reimbursements, severance pay, fringe benefits, stock, stock options, or any other ownership, equity, or profits interests in the Company and its affiliates, or their affiliates; (c) all claims for breach of contract, wrongful termination, and
breach of the implied covenant of good faith and fair dealing; (d) all tort claims, including claims for fraud, defamation, emotional distress, and discharge in violation of public policy; and (e) all federal, state, and local statutory
claims, including claims for discrimination, harassment, retaliation, attorneys’ fees, or other claims arising under the federal Civil Rights Act of 1964 (as amended), the federal Americans with Disabilities Act of 1990 (as amended), and the
federal Employee Retirement Income Security Act of 1974 (as amended). 
 Notwithstanding the foregoing, I understand that the
following rights or claims are not included in the Released Claims: (a) any rights or claims for indemnification I may have pursuant to any written indemnification agreement with the Company or its affiliate to which I am a party; the charter,
bylaws, or operating agreements of the Company or its affiliate; or under applicable law; or (b) any rights that cannot be waived as a matter of law. In addition, I understand that nothing in this Release prevents me from filing, cooperating
with, or participating in any proceeding before the Equal Employment Opportunity Commission, the Department of Labor or any other government agency, except that I hereby waive my right to any monetary benefits in connection with any such claim,
charge or proceeding. I hereby represent and warrant that, other than the claims identified in this paragraph, I am not aware of any claims I have or might have that are not included in the Released Claims. 

I hereby represent that I have been paid all compensation owed and for all hours worked; I have received all the leave and leave benefits
and protections for which I am eligible pursuant to the Family and Medical Leave Act or otherwise; and I have not suffered any on-the-job injury for which I have not already filed a workers’ compensation claim. 

  
 1 

 I acknowledge that to become effective, I must sign and return this Release to the Company
so that it is received not later than fourteen (14) days following the date it is provided to me or such other date as specified by the Company. 

 

	
	ELIGIBLE EMPLOYEE
	
	
Printed Name:                     
                                         
    

	
	
Signature:                      
                                         
          

	
	
Date:                       
                                         
                 

  
 2

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