Document:

Registration Rights Agreement

 Exhibit 10.71 
 REGISTRATION RIGHTS AGREEMENT 
 THIS REGISTRATION RIGHTS AGREEMENT (the “Agreement”) is entered
into as of September 30, 2008 by and among Oxford Finance Corporation, Compass Horizon Funding Company LLC, CIT Healthcare LLC (each, a “Purchaser” and collectively, the “Purchasers”) and Anesiva, Inc., a Delaware
corporation (the “Company”). 
 RECITALS 
 A. Concurrently with the execution of this Agreement, each Purchaser is acquiring from the Company a Warrant to Purchase Stock (each, a the “Warrant” and collectively, the “Warrants”) pursuant to
which such Purchaser has rights to acquire from the Company the Shares (as defined in the Warrant), which Shares when issued shall be shares of the Company’s common stock, $0.001 par value per share (“Common Stock”). 
 B. By this Agreement, Purchaser and the Company desire to set forth certain registration rights of the Shares all as provided herein. 
 NOW, THEREFORE, in consideration of the premises and the mutual promises, covenants and conditions hereinafter set forth, the parties hereto mutually
agree as follows: 
 1 REGISTRATION RIGHTS. The company covenants and agrees as follows: 
 1.1 Definitions. For purposes of this Section 1: 
 (a) The term “register,” “registered,” and “registration” refer to a registration effected by preparing and
filing a registration statement or similar document in compliance with the Securities Act of 1933, as amended, or any successor statute, and the rules and regulations thereunder (the “Securities Act”), and the declaration or ordering of
effectiveness of such registration statement or document; 
 (b) The term “Registrable Securities” means
(i) the Shares issued and issuable upon exercise or conversion of the Warrants, and (ii) any Common Stock or other securities of the Company issued as (or issuable upon the conversion or exercise of any warrant, right or other security
which is issued as) a dividend or other distribution with respect to, or in exchange for or in replacement of, such Shares. 
 (c) The terms “Holder” or “Holders” means any and all Purchasers and their respective qualifying transferees under subsection 1.8 hereof who hold Registrable Securities. 
 (d) The term “SEC” means the Securities and Exchange Commission. 
 (e) The terms “Form S-1,” “Form S-3” etc. shall mean those forms with such designations as are required by the SEC and
any successor or replacement forms adopted by the SEC. 
 1.2 Company Registration. 
 (a) Registration. If at any time or from time to time, the Company shall determine to register any of its securities for the
account of any of its shareholders (including, without limitation, any registration in which the Company also offers securities for its own account, but excluding any registration pursuant to which Company securities are registered only for the
account of the Company) , other than a registration on Form S-8 relating solely to employee stock option or purchase plans or on Form S-4 relating solely to an SEC Rule 145 transaction, the Company will: 
 (i) promptly give to each Holder written notice thereof (which shall include a list of the jurisdictions in which the Company intends to
attempt to qualify such securities under the applicable blue sky or other state securities laws); and 
  

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 (ii) include in such registration (and qualifications), and in any underwriting involved
therein, all the Registrable Securities specified in a written request or requests, made within 20 days after receipt of such written notice from the Company, by any Holder or Holders, except as set forth in subsection 1.2(c) below. 
 (b) Underwriting. If the registration of which the Company gives notice is for an underwritten public offering,, the Company shall
so advise the Holders as a part of the written notice given pursuant to subsection 1.2(a)(i). In such event the right of any Holder to registration pursuant to this subsection 1.2 shall be conditioned upon such Holder’s participation in
such underwriting and the inclusion of such Holder’s Registrable Securities in the underwriting to the extent provided herein. All Holders proposing to distribute their securities through such underwriting shall (together with the Company and
the other shareholders distributing their securities through such underwriting) enter into an underwriting agreement in customary form (and not inconsistent with the terms hereof) with the underwriter or underwriters selected for such underwriting
by the Company. 
 (c) In the case of any registration of Common Stock by the Company in an underwritten public offering, if
the managing underwriters give written advice to the Company that marketing factors require a limitation on the number of shares of Common Stock (or other securities convertible into or exercisable or exchangeable for Common Stock) to be offered and
sold by stockholders of Company in such offering, there shall be included in the offering: (i) first, all securities proposed by Company to be sold for its account; and (ii) second, that number of shares of Common Stock, if any, requested
to be included in such registration statement by Holders and by other stockholders of the Company having contractual rights to include shares in such registration, on a pro rata basis based upon the number of shares of Common Stock each Holder and
each such other stockholder beneficially owns. 
 1.3 Expenses of Registration. All expenses incurred in connection with any
registration, qualification or compliance pursuant to this Section 1 including without limitation, all registration, filing and qualification fees, printing expenses, underwriting fees, discounts and commissions (other than underwriting fees,
discounts and commissions in respect of Registrable Securities included in such registration), fees and disbursements of counsel for the Company and expenses of any special audits incidental to or required by such registration, shall be borne by the
Company. All expenses of any registered offering not otherwise borne by the Company will be borne pro rata among the Holders, any other shareholders of the Company participating in such offering and the Company. 
 1.4 Registration Procedures. In the case of each registration, qualification or compliance effected by the Company pursuant to this
Agreement, the Company will keep each Holder participating therein advised in writing as to the initiation of each registration, qualification and compliance and as to the completion thereof. At its expense the Company will: 
 (a) Prepare and file with the SEC a registration statement with respect to such Registrable Securities and use all reasonable efforts to
cause such registration statement to become effective, and, upon the request of the Holders of a majority of the Registrable Securities registered thereunder, keep such registration statement effective for up to 90 days (the “Effective
Period”). 
 (b) Prepare and file with the SEC such amendments and supplements to such registration statement and the
prospectus used in connection with such registration statement as may be necessary to comply with the provisions of the Securities Act with respect to the disposition of all securities covered by such registration statement for the period set forth
in (a) above. 
  

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 (c) Furnish to the Holders such numbers of copies of a prospectus, including a
preliminary prospectus, in conformity with the requirements of the Securities Act, and such other documents as they may reasonably request in order to facilitate the disposition of Registrable Securities owned by them. 
 (d) Use all reasonable efforts to register and qualify the securities covered by such registration statement under such other securities
or Blue Sky laws of such jurisdictions as shall be reasonably requested by the Holders, provided that the Company shall not be required in connection therewith or as a condition thereto to qualify to do business or to file a general consent to
service of process in any such states or jurisdictions. 
 (e) In the event of any underwritten public offering, enter into
and perform its obligations under an underwriting agreement, in usual and customary form, with the managing underwriter(s) of such offering. Each Holder participating in such underwriting shall also enter into and perform its obligations under such
an agreement provided that all other shareholders of the Company participating in such offering do the same. 
 (f) Notify
each Holder of Registrable Securities covered by such registration statement at any time when a prospectus relating thereto is required to be delivered under the Securities Act of the happening of any event as a result of which the prospectus
included in such registration statement, as then in effect, includes an untrue statement of a material fact or omits to state a material fact required to be stated therein or necessary to make the statements therein not misleading in the light of
the circumstances then existing. 
 1.5 Indemnification. 
 (a) To the extent permitted by law, the Company will indemnify each Holder of Registrable Securities and each of its officers, directors
and partners, and each person controlling such Holder within the meaning of Section 15 of the Securities Act (“controlling person”), and each underwriter, if any, and each controlling person of such underwriter, with respect to which
registration, qualification or compliance of Registrable Securities has been effected pursuant to this Agreement, against all claims, losses, expenses, damages and liabilities (or actions in respect thereto) arising out of or based on any untrue
statement (or alleged untrue statement) of a material fact contained in any registration statement, preliminary prospectus, final prospectus, or any amendments or supplements thereto, or any other solicitation materials incident to any such
registration, qualification or compliance, or based on any omission (or alleged omission) to state therein a material fact required to be stated therein or necessary to make the statement therein not misleading, or any violation or alleged violation
by the Company of the Securities Act, the Securities Exchange Act of 1934, as amended, and the rules and regulations thereunder (“Exchange Act”) or any state securities law applicable to the Company or any rule or regulation promulgated
any such state law and relating to action or inaction required of the Company in connection with any such registration, qualification or compliance, and will reimburse each such Holder, each of its officers, directors and partners, and each person
controlling such Holder, each such underwriter and each person who controls any such underwriter, within a reasonable amount of time after incurred for any reasonable legal and any other expenses reasonably incurred in connection with investigating,
defending or settling any such claim, loss, damage, liability or action; provided, however, that the indemnity agreement contained in this subsection 1.5(a) shall not apply to amounts paid in settlement of any such claim, loss,
damage, liability, or action if such settlement is effected without the consent of the Company (which consent shall not be unreasonably withheld or delayed); and provided further, that the Company will not be liable in any such
case to the extent that any such claim, loss, damage or liability arises out of or is based on any untrue statement or omission made in reliance upon and conformity with written information furnished to the Company specifically for use therein by an
instrument duly executed by such Holder. 
 (b) To the extent permitted by law, each Holder will, if Registrable Securities
held by or issuable to such Holder are included in the securities as to which such registration, qualification or compliance is being effected, indemnify the Company, each of its directors, officers and controlling persons, each underwriter, if

  

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any, of the Company’s securities covered by such a registration statement, and each controlling person of such underwriter, and each other Holder, each
of its officers, directors, partners and controlling persons, against all claims, losses, expenses, damages and liabilities (or actions in respect thereof) arising out of or based on any untrue statement (or alleged untrue statement) of a material
fact contained in any such registration statement, preliminary prospectus, final prospectus, or any amendments or supplements thereto, or any other solicitation materials incident to any such registration, qualification or compliance, or any
omission (or alleged omission) to state therein a material fact required to be stated therein or necessary to make the statements therein not misleading, or any violation or alleged violation by the Holder of Securities Act or Exchange Act or any
state securities law applicable to the Holder or any rule or regulation promulgated any such state law, and will reimburse the Company, such Holders, such directors, officers, partners, persons or underwriters for any reasonable legal or any other
expenses reasonably incurred in connection with investigating, defending or settling any such claim, loss, damage, liability or action, in each case to the extent, but only to the extent, that such untrue statement (or alleged untrue statement) or
omission (or alleged omission) is made in such registration statement, preliminary prospectus, final prospectus, or any amendments or supplements thereto, or any other solicitation materials incident to any such registration, qualification or
compliance, in reliance upon and in conformity with written information furnished to the Company specifically for use therein by an instrument duly executed by such Holder; provided, however, that the indemnity agreement contained in
this subsection 1.5(b) shall not apply to amounts paid in settlement of any such claim, loss, damage, liability or action if such settlement is effected without the consent of the Holder, (which consent shall not be unreasonably withheld or
delayed); and provided further, that the total amount for which any Holder shall be liable under this subsection 1.5(b) shall not in any event exceed the aggregate net proceeds received by such Holder from the sale of
Registrable Securities held by such Holder in such registration. 
 (c) Each party entitled to indemnification under this
subsection 1.5 (the “Indemnified Party”) shall give notice to the party required to provide indemnification (the “Indemnifying Party”) promptly after such Indemnified Party has actual knowledge of any claim as to which
indemnity may be sought, and shall permit the Indemnifying Party to assume the defense of any such claim or any litigation resulting therefrom; provided that counsel for the Indemnifying Party, who shall conduct the defense of such claim or
litigation, shall be approved by the Indemnified Party (whose approval shall not be unreasonably withheld), and the Indemnified Party may participate in such defense at such party’s expense; and provided further, that the failure of any
Indemnified Party to give notice as provided herein shall not relieve the Indemnifying Party of its obligations hereunder, unless such failure resulted in prejudice to the Indemnifying Party; and provided further, that an Indemnified Party (together
with all other Indemnified Parties which may be represented without conflict by one counsel) shall have the right to retain one separate counsel, with the fees and expenses to be paid by the Indemnifying Party, if representation of such Indemnified
Party by the counsel retained by the Indemnifying Party would be inappropriate due to actual or potential differing interests between such Indemnified Party and any other party represented by such counsel in such proceeding. No Indemnifying Party,
in the defense of any such claim or litigation, shall, except with the consent of each Indemnified Party, consent to entry of any judgment or enter into any settlement which does not include as an unconditional term thereof the giving by the
claimant or plaintiff to such Indemnified Party of a release from all liability in respect to such claim or litigation. 
 (d)
In order to provide for just and equitable contribution in circumstances in which the indemnification provided for in this Section 1.5 is due in accordance with its terms but for any reason is judicially determined to be unenforceable against
the Indemnifying Party or otherwise unavailable to the Indemnified Party in respect to any losses, claims, damages and liabilities referred to herein, then the Indemnifying Party shall, in lieu of indemnifying such Indemnified Party, contribute to
the amount paid or payable by such Indemnified party as a result of such losses, claims, damages or liabilities to which such party may be subject in such proportion as is appropriate to reflect the relative fault of the Company, on the one hand,
and the selling Holders, on the other hand, in connection with the statements or omissions which resulted in such losses, claims, damages or liabilities, as well as any other relevant equitable considerations. The relative fault of the Company and
such selling Holders shall be determined by reference to, among other things, whether the untrue or alleged untrue statement, or omission or alleged omission, of material fact related to the information supplied by the Company or such selling
Holders and the parties’ relative intent, knowledge, access to information and opportunity to correct or prevent such statement or 

  

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omission. The Company and Holders agree that it would not be just and equitable if contribution pursuant to this Section 1.5(d) were determined by pro
rata allocation or any other method of allocation which does not take account of the equitable considerations referred to above. Notwithstanding the provisions of this Section 1.5(d), (i) in no case shall any Holder be liable or
responsible for any amount in excess of the net proceeds received by such Holder from the sale of Registrable Securities pursuant to such registration; and (ii) no person adjudged guilty of fraudulent misrepresentation (within the meaning of
Section 11(f) of the Securities Act) shall be entitled to contribution from any person who was not adjudged guilty of such fraudulent misrepresentation. Any party entitled to contribution shall, promptly after receipt of notice of commencement
of any action, suit or proceeding against such party in respect of which a claim for contribution may be made against another party or parties under this Section 1.5(d), notify such party or parties from whom contribution may be sought, but the
omission so to notify such party or parties from whom contribution may be sought shall not, in the absence of actual prejudice to such party or parties, relieve it or them from such contribution obligation. No party shall be liable for contribution
with respect to any action, suit, proceeding or claim settled without its written consent. 
 1.6 Information by Holder. Any
Holder or Holders of Registrable Securities included in any registration shall promptly furnish to the Company such information regarding such Holder or Holders and the distribution proposed by such Holder or Holders as the Company may request in
writing and as shall be required in connection with any registration, qualification or compliance referred to herein. 
 1.7 Rule
144 Reporting. With a view to making available to Holders the benefits of certain rules and regulations of the SEC which may permit the sale of the Registrable Securities to the public without registration, the Company agrees at all times to:

 (a) make and keep public information available, as those terms are understood and defined in SEC Rule 144; 

(b) file with the SEC in a timely manner all reports and other documents required of the Company under the Securities Act and the
Exchange Act; and 
 (c) so long as a Holder owns any Registrable Securities, to furnish to such Holder forthwith upon request
a written statement by the Company as to its compliance with the reporting requirements of said Rule 144, and of the Securities Act and the Exchange Act, a copy of the most recent annual or quarterly report of the Company, and such other
reports and documents so filed by the Company as the Holder may reasonably request in complying with any rule or regulation of the SEC allowing the Holder to sell any such securities without registration. 
 1.8 Transfer of Registration Rights. Holders’ rights hereunder may only be assigned to a transferee or assignee of a Holder’s
Registrable Securities not sold to the public, that (a) is an affiliate of such Holder, or (b) acquires at least 150,000 Shares (as adjusted for stock splits and combinations); provided, that the Company is given written notice by such
Holder at the time of or within a reasonable time after said transfer, stating the name and address of said transferee or assignee and identifying the securities with respect to which such registration rights are being assigned. 
 1.9 Termination of Registration Rights. The right of any Holder to inclusion of Registrable Securities in any registration pursuant to
Section 1.2 hereof shall terminate upon the earlier of: (i) the date ten (10) years from the date of this Agreement; or (ii) such time as such Holder (together with its affiliates) holds less than twenty-five percent
(25%) of the Shares originally represented by such Holder’s Warrant. Upon such termination, such shares shall cease to be “Registrable Securities” hereunder for all purposes. 
  

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	 	2	GENERAL. 

 2.1 Waivers and
Amendments. With the written consent of the record or beneficial holders of at least a majority of the Registrable Securities, the obligations of the Company and the rights of the Holders of the Registrable Securities under this agreement may be
waived (either generally or in a particular instance, either retroactively or prospectively, and either for a specified period of time or indefinitely), and with the same consent the Company, when authorized by resolution of its Board of Directors,
may enter into a supplementary agreement for the purpose of adding any provisions to or changing in any manner or eliminating any of the provisions of this Agreement; provided, however, that no such modification, amendment or waiver shall reduce the
aforesaid percentage of Registrable Securities without the consent of all of the Holders of the Registrable Securities. Upon the effectuation of each such waiver, consent, agreement of amendment or modification, the Company shall promptly give
written notice thereof to the record holders of the Registrable Securities who have not previously consented thereto in writing. This Agreement or any provision hereof may be changed, waived, discharged or terminated only by a statement in writing
signed by the party against which enforcement of the change, waiver, discharge or termination is sought, except to the extent provided in this subsection 2.1. 
 2.2 Governing Law. This Agreement shall be governed in all respects by the laws of the State of California as such laws are applied to agreements between California residents entered into and to be
performed entirely within California. 
 2.3 Successors and Assigns. Except as otherwise expressly provided herein, the
provisions hereof shall inure to the benefit of, and be binding upon, the successors, assigns, heirs, executors and administrators of the parties hereto. 
 2.4 Entire Agreement. Except as set forth below, this Agreement and the other documents delivered pursuant hereto constitute the full and entire understanding and agreement between the parties with
regard to the subjects hereof and thereof. 
 2.5 Notices, etc. All notices and other communications required or permitted
hereunder shall be in writing and shall be deemed effectively given: (i) when sent by confirmed electronic mail or facsimile if sent during normal business hours of the recipient; (ii) five days after having been mailed by first class
mail, postage prepaid, certified or registered mail, return receipt requested, addressed (a) if to Holder, at such Holder’s address(es) as set forth in the respective Warrants, or at such other address(es) as such Holder shall have
furnished to the Company in writing, or (b) if to the Company, at the Company’s address set forth in the Warrants, or at such other address as the Company shall have furnished to the Holder in writing. 
 2.6 Severability. In case any provision of this Agreement shall be invalid, illegal, or unenforceable, the validity, legality and
enforceability of the remaining provisions of this Agreement or any provision of the other Agreement s shall not in any way be affected or impaired thereby. 
 2.7 Titles and Subtitles. The titles of the sections and subsections of this Agreement are for convenience of reference only and are not to be considered in construing this Agreement. 
 2.8 Counterparts. This Agreement may be executed in any number of counterparts, each of which shall be an original, but all of which
together shall constitute one instrument. 
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 IN WITNESS WHEREOF, the parties have caused this Registration Rights Agreement to be executed by their
duly authorized representatives as of the date first above written. 
  

									
	PURCHASERS:	 		 	COMPANY
			
	OXFORD FINANCE CORPORATION	 		 	ANESIVA, INC.
					
	By:	 	/s/ Tim A. Lex	 		 	By:	 	/s/ Jean-Frédéric Viret
	Name:	 	Tim A. Lex	 		 	Name:	 	Jean-Frédéric Viret
	Title:	 	Chief Operating Officer	 		 	Title:	 	Vice President and Chief Financial Officer

  

					
	 COMPASS HORIZON FUNDING
 COMPANY
LLC

		
	By:	 	 Horizon Technology Finance
 Management LLC,
its adviser

			
		 	By:	 	/s/ Robert D. Pomeroy, Jr.
		 	Name:	 	Robert D. Pomeroy, Jr.
		 	Title:	 	Chief Executive Officer
	
	CIT HEALTHCARE LLC
		
	By:	 	/s/ Jonathan L. Domm
	Name:	 	Jonathan L. Domm
	Title:	 	Senior Vice President

  

 -7-Letter Agreement

 Exhibit 10.72 
 General Electric Capital Corporation 
 Life Science Finance 
 83 Wooster Heights Road, Fifth Floor 
 Danbury,
Connecticut 06810 
 September 30, 2008 
 Anesiva, Inc.

 650 Gateway Boulevard 
 South San Francisco, CA 94080

  

	 	Re:	Payoff Letter 

 Ladies and Gentlemen: 
 Reference is made to (i) the Equipment Loan and Security Agreement, dated as of August 30, 2007 (as amended, restated, supplemented or
otherwise modified to date, the “Loan Agreement”; all undefined capitalized terms used herein but not defined herein shall have the meanings given to such terms in the Loan Agreement), between Anesiva, Inc., a Delaware corporation
(the “Borrower”) and General Electric Capital Corporation, a Delaware corporation (“Existing Lender”), and (ii) the other Debt Documents and all guaranties, security agreements, mortgages, subordination
agreements, intercreditor agreements, pledge agreements, blocked account agreements, notes and other documents and instruments relating thereto (together with the Loan Agreement, collectively, the “Credit Documents”). Existing
Lender understands that on the Payoff Effective Time (as defined below), the Borrower will repay in full all Obligations in connection with the Credit Documents. Notwithstanding any provision in this letter agreement (this
“Agreement”) to the contrary, any warrants to purchase any equity interests of Borrower issued by Borrower to Existing Lender or any of its affiliates (each of the foregoing, a “Warrant” and, collectively, the
“Warrants”) and any documents relating to any Warrant or equity interests governed or to be governed by the Warrants (including, but not limited to, any investor rights agreements, voting agreements and shareholder agreements) or
any other rights to acquire an equity position in Borrower (the “Warrant Documents”) shall be excluded from the definition of “Credit Documents” and each of the Warrants and Warrant Documents shall expressly survive the
payoff of the Payoff Amount (as defined below) and shall not be affected by this Agreement. 
 Upon Existing Lender’s receipt of
(a) a federal funds wire transfer in the amount of $10,717,968.64, subject to per diem adjustment as set forth on Schedule A attached hereto (the “Payoff Amount”), which amount represents all Obligations as more fully described
on Schedule A attached hereto, and (b) a fully executed counterpart of this Agreement signed by the Borrower (the time at which all of the conditions in the foregoing clauses (a) and (b) shall first be satisfied is herein referred to
as the “Payoff Effective Time”), Existing Lender agrees and acknowledges that: (i) all outstanding Obligations shall be paid and satisfied in full and discharged, terminated and released, other than those obligations therein
that expressly survive termination, (ii) all security 

 
interests and other liens granted to or held by Existing Lender in any assets and properties of the Borrower and Corgentech, Inc., as security for the
Obligations (the “Collateral”) shall be satisfied, released and discharged, without recourse, representation, warranty or other assurance of any kind, (iii) the Credit Documents shall terminate and be of no further force or
effect other than those provisions therein that expressly survive termination and (iv) the Borrower shall be automatically authorized to file the UCC termination statements attached hereto as Exhibit A evidencing the release of Existing
Lender’s security interests and other liens in the Collateral. 
 Further, Existing Lender agrees to take all reasonable additional
steps reasonably requested by the Borrower as may be necessary to release its security interests in the Collateral. The Borrower agrees to pay Existing Lender for all costs and expenses incurred by Existing Lender in connection with the matters
referred to in the previous sentence, and acknowledges that Existing Lender’s execution of and/or delivery of any documents releasing any security interest or claim in any property of the Borrower as set forth herein is made without recourse,
representation, warranty or other assurance of any kind by Existing Lender as to Existing Lender’s rights in any collateral security for amounts owing under the Credit Documents, the condition or value of any Collateral, or any other matter.
The Borrower hereby confirms that the commitments, if any, of Existing Lender to make any advances and any other extensions of credit under the Credit Documents are terminated as of the date of this Agreement, and, as of the date of this Agreement,
Existing Lender shall not have any further obligation, if any, to make any advances or any other extensions of credit to the Borrower. Notwithstanding anything to the contrary contained herein or in any of such releases or other documents, the
obligations and liabilities of the Borrower to Existing Lender under or in respect of the Credit Documents (including, without limitation, the Obligations) insofar as such obligations and liabilities survive termination of the Credit Documents shall
continue in full force and effect in accordance with their terms. 
 The Payoff Amount referred to above should be sent by federal funds wire
transfer to Deutsche Bank Trust Company Americas, New York, New York. If the Payoff Amount is not received by the Existing Lender on or before 5:00 p.m. (New York time) on September 30, 2008, then this Agreement shall terminate and be of no
further force or effect. 
 Notwithstanding anything herein to the contrary, if at any time on or after the Payoff Effective Time, all or any
portion of the Payoff Amount paid to Existing Lender is voided or rescinded or must otherwise be returned by Existing Lender upon Borrower’s insolvency, bankruptcy, reorganization or otherwise, all as though such payment had not been made, the
obligation to pay such amount so voided, rescinded or returned shall be reinstated. 
  

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 In addition, effective upon the Payoff Effective Time, the Borrower releases the Existing Lender and its
affiliates and subsidiaries and their respective officers, directors, employees, shareholders, agents, attorney’s and representatives as well as their respective successors and assigns from any and all claims, obligations, rights, causes of
action, and liabilities, of whatever kind or nature, whether known or unknown, whether foreseen or unforeseen, arising on or before the date hereof, which the Borrower ever had, now have or hereafter can, shall or may have for, upon or by reason of
any matter, cause or thing whatsoever, which are based upon, arise under or are related to the Credit Documents (the “Released Matters”). Borrower acknowledges that the agreements in this paragraph are intended to be in full
satisfaction of all or any alleged injuries or damages arising in connection with the Released Matters. 
 Without limiting the generality of
the foregoing, Borrower hereby waives the provisions of any statute that prevents a general release from extending to claims unknown by the releasing party. 
 By entering into this release, Borrower recognizes that no facts or representations are ever absolutely certain and it may hereafter discover facts in addition to or different from those which it presently knows or
believes to be true, but that it is the intention of Borrower to hereby to fully, finally and forever settle and release all matters, disputes and differences, known or unknown, suspected or unsuspected; accordingly, if Borrower should subsequently
discover that any fact that it relied upon in delivering this release was untrue, or that any understanding of the facts was incorrect, Borrower shall not be entitled to set aside this release by reason thereof, regardless of any claim of mistake of
fact or law or any other circumstances whatsoever. Borrower acknowledges that it is not relying upon and has not relied upon any representation or statement made by Existing Lender with respect to the facts underlying this release or with regard to
Borrower’s rights or asserted rights. 
 This release may be pleaded as a full and complete defense and/ or as a cross-complaint or
counterclaim against any action, suit, or other proceeding that may be instituted, prosecuted or attempted in breach of this release. Borrower acknowledges that the release contained herein constitutes a material inducement to Existing Lender to
enter into this Agreement and that Existing Lender would not have done so but for Existing Lender’s expectation that such release is valid and enforceable in all events. 
 The Payoff Amount has been calculated assuming that the proceeds of all checks or similar instruments for the payment of money (collectively,
“Checks”) that have been received by Existing Lender and credited to the Borrower’s account with Existing Lender are good collected funds. In consideration of Existing Lender’s release of the Liens and security interests
in and to any Collateral, the Borrower agrees to reimburse Existing Lender for all losses and liabilities that Existing Lender may incur at any time as a result of any nonpayment, claim, refund, or chargeback of any Check together with any expenses
or other charges incident thereto. Further, the Borrower agrees to reimburse Existing Lender for all losses and liabilities that Existing Lender may incur in connection with any deposit account control agreement, provider account agreement or
similar agreement entered into in connection with the Credit Documents. The amount of any such losses or liabilities reimbursed hereunder shall be paid to Existing Lender promptly by the Borrower upon Existing Lender’s demand therefor, and the
amount of such demand shall be conclusive upon the Borrower in the absence of manifest error. 
  

 3 

 This Agreement shall be governed by the internal laws of the State of Connecticut. EACH PARTY HERETO
HEREBY WAIVES ITS RESPECTIVE RIGHTS TO A TRIAL BY JURY. No party may assign its rights, duties or obligations under this Agreement without the prior written consent of the other parties. No rights are intended to be created under this Agreement
for the benefit of any Person not a party hereto. This Agreement may not be modified or waived except with the written consent of the parties hereto. This Agreement may be executed in any number of separate counterparts, each of which shall,
collectively and separately, constitute one agreement. Delivery of an executed counterpart of this Agreement by telefacsimile or electronic transmission shall be equally as effective as delivery of an original executed counterpart. The undersigned
parties have signed below to indicate their consent to be bound by the terms and conditions of this Agreement. 
 [Signature Page Follows]

  

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 If you need additional information, please do not hesitate to contact us. 
  

					
	Very truly yours,
	
	GENERAL ELECTRIC CAPITAL CORPORATION
		
	By:	 	/s/ Jason Dufour
		 	Name:	 	Jason Dufour
		 	Title:	 	Duly Authorized Signatory

 ANESIVA, INC. 
 PAYOFF LETTER 
 SIGNATURE PAGE 

			
	 ACCEPTED AND AGREED
 AS OF THIS 30th DAY OF

 September 2008

	
	ANESIVA, INC.
		
	By:	 	/s/ Jean-Frédéric Viret
	Name:	 	Jean-Frédéric Viret
	Title:	 	Vice President and Chief Financial Officer

 ANESIVA, INC. 
 PAYOFF LETTER 
 SIGNATURE PAGE

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