Document:

Vertex Energy, Inc. 8-K

Exhibit 10.1

 

	WHITEBOX
                                          

        ADVISORS
        LLC 

        3033
        Excelsior Boulevard 

        Suite
        500 

        Minneapolis,
MN 55416 
	HIGHBRIDGE
                                         CAPITAL MANAGEMENT, LLC 

        277
        Park Avenue 

        23rd
        Floor 

        New
        York, NY 10172 
	BLACKROCK
                                         FINANCIAL MANAGEMENT, INC. and certain of its affiliates, on behalf of funds and accounts
                                         under management 

        40
        East 52nd Street 

        New
        York, NY 10022 

	 	 	 
	CHAMBERS
                                         ENERGY CAPITAL IV, LP 

        600 Travis Street

        Suite
        4700 

        Houston,
        TX 77002

         
	CROWDOUT
                                         CAPITAL LLC  

        CROWDOUT
        CREDIT  

        OPPORTUNITIES
        FUND LLC 

        3001
        S. Lamar Boulevard 

        Suite
        A-300 

        Austin,
        TX 78704 

	 	 	 	 

PERSONAL
AND CONFIDENTIAL

 

February
17, 2022

 

Vertex
Refining Alabama LLC 

c/o
Vertex Energy, Inc. 

1331
Gemini Street 

Suite
250 

Houston,
TX 77058

 

Project
Vulcan II

Commitment Letter

 

Ladies
and Gentlemen:

 

You
have advised Whitebox Advisors LLC on behalf of certain funds managed or advised by Whitebox Advisors LLC (collectively,
“Whitebox”), Highbridge Capital Management, LLC on behalf of certain funds managed or advised by
Highbridge Capital Management, LLC (collectively, “Highbridge”), BlackRock Financial Management, Inc. on
behalf of certain funds and accounts managed or advised by BlackRock Financial Management, Inc. or its affiliates (collectively,
“BlackRock”), Chambers Energy Capital IV, LP (“Chambers”), CrowdOut Capital LLC
(“CrowdOut Capital”), CrowdOut Credit Opportunities Fund LLC (“CrowdOut Credit”,
and together with Chambers, CrowdOut Capital and the undersigned affiliates of Whitebox, Highbridge and BlackRock, collectively, the
“Commitment Parties,” “we,” or “us”) that Vertex
Energy, Inc. (the “Parent”), through its indirect wholly-owned subsidiary, Vertex Refining Alabama LLC, a
Delaware limited liability company (“Vertex Alabama” or “you”), intends (by
assignment from Vertex Energy Operating, LLC, a Texas limited liability company) to acquire (the
“Acquisition”) a refinery and related assets located in Mobile, Alabama (the “Target
Assets”) pursuant to that certain Sale and Purchase Agreement, dated as of May 26, 2021 (the “Acquisition
Agreement”), among Vertex Energy Operating LLC, as the Buyer, and Equilon Enterprises LLC d/b/a Shell Oil Products US,
Shell Chemical LP, and Shell Oil Company (the “Seller”). The Acquisition, together with the financing
transactions, including the Facility, contemplated herein, are referred to herein as the “Transactions”.
Capitalized terms used but not defined herein shall have the meanings assigned to them in the Summary of Principal Terms and
Conditions attached hereto as Exhibit A (the “Term Sheet”). This commitment letter, including Schedule I,
the Term Sheet, Summary of Terms And Conditions: Warrants attached hereto as Exhibit B (the “Warrant Term
Sheet”) and the Summary of Additional Conditions attached hereto as Exhibit C are referred to herein collectively as
the “Commitment Letter”.

 

     

     

    

 

1.            Commitment.
Based upon the foregoing and subject to the terms and conditions expressly set forth in this letter and in the Term Sheet, each
of the Commitment Parties, severally and not jointly, agrees to provide a portion of the Facility on the Funding Effective Date
in the aggregate principal amount set forth opposite such Commitment Party’s name on Schedule I hereto (as to each Commitment
Party, its “Agreed Commitment Amount”). Each Commitment Party’s commitment is made solely on behalf
of its respective managed funds and accounts and does not in any way include a commitment or other arrangement from any other
non-affiliated institution.

 

2.            Appointment
of Roles. You hereby agree to appoint a mutually acceptable third party to act as sole administrative agent and collateral
agent (in such capacities, the “Administrative Agent”) for the Facility; provided that Cantor Fitzgerald
Securities shall be mutually acceptable.

 

It
is understood and agreed that, except for Oppenheimer & Co., Inc., no agents, co-agents, arrangers, co-arrangers, bookrunners,
managers, or co-managers will be appointed, no titles will be awarded, and no compensation (other than compensation expressly
contemplated by this Commitment Letter, the Term Sheet and the Fee Letter) will be paid in connection with the Facility unless
you and we shall so agree.

 

3.            Fees.
As additional consideration for funding the Facility, you agree to pay to us the fees set forth in this Commitment Letter and
in the Fee Letter, dated as of the date hereof (the “Fee Letter”), between you and the Commitment Parties.
Once paid, such fees shall not be refundable under any circumstances, except as otherwise contemplated by this Commitment Letter
or the Fee Letter, as applicable, or as agreed in writing by the parties hereto. The payment of the Alternative Financing Fee
(as defined below) and the Ticking Fee (as defined in the Term Sheet) to each Commitment Party shall be made without deduction
or withholding for any taxes, except as required by applicable law. If any applicable law requires the deduction or withholding
of any tax from the payment of the Alternative Financing Fee or the Ticking Fee, as applicable, to a Commitment Party, then the
sum payable with respect to such fee shall be increased as necessary so that after such deduction or withholding has been made
(including such deductions and withholdings applicable to additional sums payable under this paragraph) the applicable Commitment
Party receives an amount equal to the sum it would have received had no such deduction or withholding been made.

 

4.            Conditions.
Notwithstanding anything in this Commitment Letter, the Term Sheet, the definitive documentation governing the Facility (the “Facility
Documentation”), or any other letter agreement or other undertaking between us and you concerning the financing
to the contrary the commitments and undertakings of the Commitment Parties hereunder are subject solely to the satisfaction of
the conditions set forth under the heading “Conditions Precedent” in Exhibit A hereto and in Exhibit C.

 

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5.            Information.
You hereby represent and warrant that (and with respect to the Target Assets, to the best of your knowledge that) (a) all written
factual information (other than (i) any financial estimates, forecasts, budgets and other projections and forward looking information
delivered by you or on behalf of you (“Projections”) and (ii) information of a general economic or industry
specific nature, the “Information”) that has been or will be made available to the Commitment Parties
by or on behalf of you or at your request by any of your representatives on your behalf in connection with the Transactions is
or will be, when furnished, correct in all material respects, and, does not or will not, when furnished, contain any untrue statement
of a material fact or omit to state a material fact necessary in order to make the statements contained therein not materially
misleading in light of the circumstances under which such statements are made (after giving effect to all supplements and updates
thereto from time to time), and (b) the Projections that have been made or will be made available to the Commitment Parties by
or on behalf of you or at your request by any of your representatives on your behalf in connection with the Transactions have
been or will be, as the case may be, prepared based upon good faith estimates and assumptions believed by you to be reasonable
at the time the related Projections are so furnished to the Commitment Parties (it being recognized by us that such Projections
are not to be viewed as facts and that actual results during the period or periods covered by any such Projections may differ
from the projected results). You agree to supplement (or, to the extent relating to Target Assets prior to the Closing Date (subject
to any limitation on your rights set forth in the Acquisition Agreement), use your commercially reasonable efforts to cause to
be promptly supplemented) the Information and the Projections from time to time until the Closing Date so that the representation
and warranties in the preceding sentence each remains correct (to your knowledge with respect to the Target Assets prior to the
Closing Date). The Commitment Parties will be entitled to use and rely primarily on the Information and the Projections without
responsibility for independent verification thereof. 

 

6.            Expenses.
You agree to pay or reimburse each Commitment Party, regardless of whether the Closing Date occurs, for all of each Commitment
Party’s actual and reasonable documented out-of-pocket costs and expenses (including, but not limited to, expenses of each
Commitment Party’s due diligence investigation, attorneys’ fees and expenses and consultant’s, and auditors,
appraisers, accountants, search and lien filing agencies, and external service providers) incurred in connection with this Commitment
Letter, the Fee Letter, and the Facility Documentation and any consents, amendments, waivers, or other modifications thereto,
limited in the case of legal expenses to the reasonable and documented or invoiced out-of-pocket legal expenses of counsel the
Commitment Parties (including Clifford Chance LLP as special counsel for BlackRock with scope and limitations as agreed by Blackrock
and the Borrower, and Sidley Austin LLP for Whitebox, Highbridge and the other Lenders), and, if reasonably necessary, (a) one
firm of local counsel in each relevant material jurisdiction (which may include a single special counsel acting in multiple jurisdictions);
and (b) in the case of an actual or perceived conflict of interest where any such person affected by such conflict informs Borrower
of such conflict, in each case, a single additional firm of counsel in each relevant jurisdiction for all similarly situated affected
persons.

 

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7.            Indemnification.
You agree to defend (subject to the Indemnified Persons’ selection of counsel), indemnify, and hold harmless each Commitment
Party and its affiliates and each Commitment Party’s and its affiliates’ respective shareholders, members, controlling
persons, officers, partners, directors, trustees, advisors, counsel, employees, and agents (each Commitment Party and each such
other person being an “Indemnified Person”), from and against any and all Indemnified Liabilities (defined
below); provided that you shall not have any obligation to any Indemnified Person hereunder with respect to any Indemnified
Liabilities to the extent such Indemnified Liabilities arise from (i) the gross negligence or willful misconduct, as determined
by a court of competent jurisdiction in a final, non-appealable order, of that Indemnified Person, (ii) a material breach of the
obligations under this Commitment Letter of such Indemnified Person (as determined by a court of competent jurisdiction in a final,
non-appealable order), or (iii) any proceeding solely between or among Indemnified Persons not arising from any act or omission
by you or any of your affiliates (other than any claim, actions, suits, inquiries, litigation, investigation or proceeding against
any Indemnified Person in its capacity or in fulfilling its role as an Administrative Agent). Notwithstanding anything to the
contrary herein, no Indemnified Person or Indemnifying Person or any of their respective officers, directors, employees, advisors,
controlling persons, members, agents and other representatives or their respective successors and assigns shall be liable for
any special, indirect, consequential or punitive damages (including, without limitation, any loss of profits, business or anticipated
savings) provided, that nothing contained in this sentence shall limit your indemnification obligations to the extent such special,
indirect, consequential or punitive damages are included in any third party claim in connection with which such Indemnified Person
is otherwise entitled to indemnification hereunder to the extent that none of the exceptions set forth in clause (i), (ii) or
(iii) to the proviso of the preceding paragraph applies to such person at such time. As used herein, “Indemnified
Liabilities” means, collectively, any and all liabilities, obligations, settlements, losses, damages (including
civil damages related to environmental liabilities), penalties, claims (including environmental liabilities), costs (including
the costs of any investigation, study, sampling, testing, abatement, cleanup, removal, remediation, or other response action necessary
to remove, remediate, clean up, or abate any hazardous materials), expenses, and disbursements of any kind or nature whatsoever
(including the reasonable fees and disbursements of counsel for the Indemnified Persons in connection with any investigative,
administrative, or judicial proceeding commenced or threatened by any person, whether or not any such Indemnified Person shall
be designated as a party or a potential party thereto, and any fees or expenses incurred by the Indemnified Persons in enforcing
this indemnity), whether based on any federal, state, or foreign laws, statutes, rules, or regulations (including securities
and commercial laws, statutes, rules, or regulations and environmental laws), on common law or equitable cause or on contract
or otherwise, that may be imposed on, incurred by, or asserted against any such Indemnified Person, in any manner relating to
or arising out of this Commitment Letter, the Fee Letter, the Facility Documentation, or the Transactions (including the Initial
Lenders’ agreement to make the Facility available to the Borrower on the terms, and subject to the conditions, set forth
herein or the use or intended use of the proceeds thereof, or any enforcement of this Commitment Letter, the Fee Letter, or the
Facility Documentation (including any sale of, collection from, or other realization upon any of the collateral or the enforcement
of any guaranty)) or any related transaction contemplated hereby or any of the use of proceeds of the Facility; provided that
the Indemnified Liabilities shall be limited in the case of legal expenses to the reasonable and documented or invoiced out-of-pocket
legal expenses of one firm of counsel for BlackRock (which as of the date hereof is Clifford Chance LLP) and one firm of counsel
for Whitebox, Highbridge and all other Indemnified Persons, taken as a whole, (which as of the date hereof is Sidley Austin LLP)
and, if reasonably necessary, of one firm of local counsel in each relevant material jurisdiction (which may include a single
special counsel acting in multiple jurisdictions) for all such Indemnified Persons, taken as a whole (and, solely in the case
of an actual or potential conflict of interest where the Indemnified Persons affected by such conflict notify you of the existence
of such conflict, of one additional firm of counsel for all affected Indemnified Persons, taken as a whole and, if necessary,
one firm of local counsel in each relevant material jurisdiction (which may include a single special counsel acting in multiple
jurisdictions) for each group of similarly situated affected Indemnified Persons, taken as a whole).

 

To
the extent the undertakings set forth in this Section 7 may be unenforceable in whole or in part because they are violative of
any law or public policy, the applicable loan party shall contribute the maximum portion that it is permitted to pay and satisfy
under applicable law to the payment and satisfaction of all Indemnified Liabilities incurred by the Indemnified Persons or any
of them. Notwithstanding any other provision of this Commitment Letter, and without limitation of your indemnification obligations
set forth herein, no party hereto shall be liable for any damages arising from the use by others of information or other materials
obtained through electronic, telecommunications, or other information transmission systems, except to the extent such damages
have been determined in a final, non-appealable judgment of a court of competent jurisdiction to have resulted from the willful
misconduct or gross negligence of such person.

 

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8.            Confidentiality;
Absence of Fiduciary Duty; Etc. You agree that you will not disclose, directly or indirectly, the Fee Letter and the contents
thereof or this Commitment Letter and the Term Sheet and the contents hereof and thereof, or the activities of the Commitment
Parties pursuant hereto or thereto, to any person without prior written approval of the Commitment Parties, except that you may
disclose (a) the Commitment Letter, the Term Sheet, the Fee Letter, and the contents hereof and thereof (i) to your officers,
directors, agents, employees, attorneys, accountants, and advisors and (ii) as required by applicable law, regulation, or compulsory
legal process (in which case you agree to provide prompt written notice thereof, such notice to be provided in advance to the
extent permitted by applicable law), (b) this Commitment Letter, the Term Sheet, and the contents hereof and thereof (but not
the Fee Letter unless redacted in a customary manner reasonably acceptable to the Commitment Parties) to the Seller, and its officers,
directors, employees, attorneys, accountants, and advisors, in each case in connection with the Transactions and on a confidential
and need-to-know basis, (c) the Commitment Letter, the Term Sheet and the contents thereof and hereof (but not the Fee Letter)
to any rating agency when required by it; provided, that prior to any disclosure, such rating agency shall undertake in
writing to preserve the confidentiality of any confidential information received by it, (d) the existence and contents of the
Term Sheet to potential lenders in connection with the Transactions, (e) this Commitment Letter, the Term Sheet, and the contents
hereof and thereof (but not the Fee Letter) to any other financing providers, including the providers of the WC Facility, not
in violation of Section 11 below, (f) this Commitment Letter, the Term Sheet, and the contents hereof and thereof (but not the
Fee Letter) to any Secured Hedge Provider or any potential Secured Hedge Provider, (g) to the extent any such information becomes
publicly available other than by reason of disclosure by you, your affiliates, or your or their respective officers, directors,
agents, employees, attorneys, accountants, or advisors in breach of this Commitment Letter and (h) the existence and contents
of this Commitment Letter and the Term Sheet in any public filing, prospectus or, subject to the last sentence of this paragraph,
press release (it being acknowledged that the fees in the Fee Letter may be included generically in projections and pro forma
information and in a generic disclosure of aggregate sources and uses contained in such syndication and other marketing materials).
Further, notwithstanding the next succeeding paragraph, we shall be permitted, in consultation with you and with your approval,
after the Funding Effective Date, to use Parent’s and Borrower’s tradenames, trademarks, logo, and information related to the
Facility in connection with marketing, press releases, or other transactional announcements or updates provided to investor or
trade publications. You agree that you will permit the applicable Commitment Party to review and approve (such approval not to
be unreasonably delayed, conditioned or withheld) any reference to such Commitment Party or any of its affiliates in connection
with the Facility or the Transactions contained in any press release or similar public disclosure prior to public release.

 

We
shall hold all non-public information regarding you, Parent and the Target Assets, and your and their respective subsidiaries
and businesses identified as such by you solely for the purpose of providing the services which are the subject of this Commitment
Letter and negotiating and consummating the transactions contemplated hereby and shall treat confidentially all such information
and shall not publish, disclose or otherwise divulge such information, in each case, in accordance with our customary procedures
for handling confidential information of such nature, it being understood and agreed by you that, in any event, we may make (a) disclosures
of such information to our respective affiliates and to our and affiliates’ respective members, controlling persons, agents, advisors,
counsel, directors, shareholders and other equity-holders (and to other persons authorized by a Commitment Party to organize,
present, or disseminate such information in connection with disclosures otherwise made in accordance with this Section 8), in
each case, to the extent directly involved in the consideration of this matter on a confidential and need-to-know basis, (b) disclosures
of such information reasonably required by any bona fide potential Lender or participant in connection with the contemplated assignment,
transfer, or participation by any such Commitment Party of any interest in the Facility or any participations therein provided,
that prior to any disclosure, such potential Lender shall undertake in writing to preserve the confidentiality of any confidential
information received by it from any of the Commitment Parties, (c) disclosure to any rating agency when required by it; provided,
that prior to any disclosure, such rating agency shall undertake in writing to preserve the confidentiality of any confidential
information received by it from any of the Commitment Parties, (d) disclosure to any Commitment Party’s financing sources
or valuation providers; provided, that prior to any disclosure, such financing source or valuation provider is informed
of the confidential nature of information received by it from any of the Commitment Parties, (e) disclosures of such information
to any investors and partners of any Commitment Party, including prospective investors in future funds and accounts, in each case,
that may or not be participating in the proposed investment; provided, that prior to any disclosure, such investor or partner
is informed of the confidential nature of information received by it from any of the Commitment Parties (and, in each case of
the foregoing clauses (b), (c), (d), and (e), such disclosures shall be permitted to such persons’ or entities’ respective affiliates,
members, employees, advisors, representatives and agents; provided, that prior to any disclosure, such parties shall be
informed of the confidential nature of information received by it), (f) disclosure required or requested pursuant to applicable
law, rule or regulation or any legal, judicial, governmental, administrative or regulatory order, authority or process, or in
connection with any public filings, whether pursuant to any securities laws or regulations or rules promulgated therefor (including
the Investment Company Act of 1940 or otherwise, including, without limitation, in connection with filings, submissions and any
other similar documentation required or customary to comply with Securities and Exchange Commission filing requirements) or representative
thereof or by the National Association of Insurance Commissioners (and any successor thereto); provided further, that unless
specifically prohibited by applicable law or court order, each Commitment Party shall make reasonable efforts to notify Borrower
of any request by any governmental authority or representative thereof (other than any such request in connection with any examination
of the financial condition or other routine examination of such Commitment Party by such governmental authority, or with respect
to any request for information by any legal, judicial, governmental, administrative, or regulatory authority that is not specific
to the confidential information provided hereunder) for disclosure of any such non-public information prior to disclosure of such
information, (g) to the extent any such information becomes publicly available other than by reason of disclosure by us, our affiliates,
or our or their respective officers, directors, agents, employees, attorneys, accountants, or advisors in breach of this Commitment
Letter, or to the extent any such information is developed independently by us, and (h) for purposes of establishing a “due
diligence” defense or to exercise rights or remedies. Our obligations under this Section 8, shall automatically expire upon
the earlier of execution and delivery of the Facility Documentation and the second anniversary of the date hereof.

 

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You
acknowledge that each Commitment Party and its affiliates and its and its respective affiliates’ managed funds and accounts may
be providing debt financing, equity capital, or other services (including, without limitation, financial advisory services) to
other companies in respect of which you may have conflicting interests regarding the transactions described herein and otherwise.
The Commitment Parties will not use confidential information obtained from you by virtue of the transactions contemplated by this
Commitment Letter or any of their other relationships with you in connection with the performance by them and their affiliates
of services for other companies, and except as expressly permitted hereby, the Commitment Parties will not furnish any such information
to such other companies. By the same token, we will not make available to you confidential information that we have obtained or
may obtain from any other customer. You also acknowledge that none of the Commitment Parties nor any of their affiliates have
any obligation to use, in connection with the transactions contemplated by this Commitment Letter or to furnish to you or your
subsidiaries, confidential information obtained by such Commitment Party and its affiliates from other companies.

 

In
connection with all aspects of each transaction contemplated by this Commitment Letter, you acknowledge and agree, and acknowledge
your affiliates’ understanding, that: (a) the Facility and any related services described in this Commitment Letter is an
arm’s-length commercial transaction between you and your affiliates, on the one hand, and the Commitment Parties, on the
other hand, (b) the Commitment Parties have not provided any investment, legal, accounting, regulatory, or tax advice with respect
to any of the Transactions, you have consulted your own investment, legal, accounting, regulatory, and tax advisors to the extent
you have deemed appropriate, and neither you, nor any of your affiliates, have received, or have relied upon, the advice of the
Commitment Parties or any of their respective affiliates or advisors regarding investment, legal, regulatory, accounting, or tax
matters, (c) you are capable of evaluating, and understand and accept, the terms, risks, and conditions of the Transactions, (d)
in connection with the financing Transactions and the process leading to such Transactions, each of the Commitment Parties has
been, is, and will be acting solely as a principal and has not been, is not, and will not be acting as an advisor, agent, or fiduciary
for you or any of your affiliates, stockholders, creditors, or employees or any other party, (e) the Commitment Parties have not
assumed and will not assume an advisory, agency, or fiduciary responsibility in your or your affiliates’ favor with respect
to any of the financing Transactions or the process leading thereto, and the Commitment Parties have no obligation to you or your
affiliates with respect to the financing Transactions except those obligations expressly set forth in this Commitment Letter,
and (f) the Commitment Parties and their respective affiliates and their and their respective affiliates’ managed funds and accounts
may be engaged in a broad range of transactions that involve interests that differ from yours and those of your affiliates, and
the Commitment Parties have no obligation to disclose any of such interests to you or your affiliates. To the fullest extent permitted
by law, you hereby waive and release any claims that you may have against the Commitment Parties with respect to any breach or
alleged breach of agency or fiduciary duty in connection with any aspect of any financing transaction contemplated by this Commitment
Letter.

 

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9.            Termination.
Except as set forth in the next paragraph, this Commitment Letter and our commitments and undertakings hereunder shall terminate
in their entirety automatically without further notice or action by us on the date (the “Termination Date”)
that is the first to occur of (a) April 1, 2022, (b) with respect to our commitments and undertakings hereunder in respect of
the Facility, consummation of the Acquisition without use of the Facility or if the Initial Lenders become aware of a breach under
Section 11 hereof, (c) the Closing Date and the release of the funds on deposit in the Escrow Account to the Borrower, (d) the
termination of the Acquisition Agreement in accordance with its terms prior to the Closing Date, and (e) the date upon which the
Borrower breaches its obligations hereunder or otherwise fails to comply with the terms and conditions of this Commitment Letter
(unless such breach or failure is cured within two (2) business days following Borrower’s receipt of notice of such breach
or failure).

 

The
Fee Letter and the compensation, reimbursement, indemnification, exclusivity, jurisdiction, absence of fiduciary relationship,
governing law, waiver of jury trial, and confidentiality provisions contained herein shall remain in full force and effect regardless
of whether the Facility Documentation shall be executed and delivered and notwithstanding the termination of this Commitment Letter
or any Lender’s commitments hereunder; provided that your obligations under this Commitment Letter (other than your
obligations with respect to confidentiality) shall automatically terminate and be superseded to the extent of any corresponding
provisions of the Facility Documentation covering the same subject matter upon the execution and delivery thereof.

 

10.          Assignment; etc. This Commitment Letter and the commitments and undertakings hereunder shall not be assignable by any party
hereto without the prior written consent of each other party hereto, and any attempted assignment shall be void and of no effect;
provided, however, that nothing contained in this paragraph shall prohibit us (in our sole discretion), subject
to the terms of this Commitment Letter, from granting participations in, or selling assignments of, all or a portion of the commitments
or the advances under the Facility; provided that notwithstanding such assignment or participation, with respect to amounts to
be funded into escrow on the Funding Effective Date or amounts to be funded to the Borrower on the Closing Date, the commitment
of the Initial Lenders to fund the Facility on the terms and conditions set forth in this Commitment Letter and the Fee Letter
will be reduced solely to the extent such other Lenders fund their commitments into escrow on the Funding Effective Date or amounts
to be funded to the Borrower on the Closing Date. This Commitment Letter is intended to be solely for the benefit of the parties
hereto and is not intended to confer any benefits upon, or create any rights in favor of, any person other than the parties hereto
and the Indemnified Persons, except that the Commitment Parties may perform the duties and activities described hereunder through
any of their respective affiliates or branches and the provisions of the final paragraph of Section 8 shall apply with equal force
and effect to any of such affiliates or branches so performing any such duties or activities. Notwithstanding the foregoing, the
Initial Lenders will be permitted to assign the Term Loans after the Closing Date, with the consent of the Borrower (not to be
unreasonably withheld or delayed); provided, in each case, that no consent of the Borrower shall be required (i) if such assignment
is made to another Lender or an affiliate or approved fund thereof or (ii) after the occurrence and during the continuance of
an event of default; provided, further, no assignments shall be made to any natural persons, the Borrower or any Guarantor. If
the consent of the Borrower is required for an assignment, its consent will be deemed given if the Borrower has not responded
within ten (10) business days of a request for such consent.

 

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11.          Exclusivity. From the date hereof until the earlier of (i) nine months from the date hereof, (ii) the date upon which the
Lenders have failed to fund all or any portion of the Term Loans within two (2) Business Days of the date such Term Loans were
required to be funded hereunder (unless such Lender notifies the Agent and the Borrower in writing that such failure is the result
of such Lender’s determination that one or more Conditions Precedent to funding in the Borrower’s control has not
been satisfied) and (iii) the Lenders otherwise elect not to pursue the transactions contemplated hereby (such period, the “Exclusivity
Period”), (A) you (i) shall not, and shall cause your affiliates, agents, representatives, counsel, consultants
and advisors and any other person acting on your or their behalf not to, other than pursuant to this Commitment Letter, directly
or indirectly solicit, participate in any negotiations or discussions with or provide or afford access to information to any third
party with respect to, or otherwise facilitate, encourage or accept any offers for or otherwise enter into any other capital financing
arrangements (whether in the form of an equity contribution, debt issuance, credit facility or otherwise) that would have the
effect of replacing all or any portion of the borrowings under the Facility (other than the Permitted Financing (defined below))
(any such transaction, an “Alternate Financing Transaction”) and (ii) shall terminate or have terminated
prior to the date hereof, and shall cause your affiliates, agents, representatives, counsel, consultants and advisors and any
other person acting on your or their behalf to terminate, any agreement or arrangement related to the foregoing to which you or
your affiliates are parties, as well as any activities and discussions related to the foregoing as may be continuing on the date
hereof with any party other than us and our representatives, in each case, other than the Permitted Financing, and (B) the Commitment
Parties shall have the exclusive right to provide any senior secured financing for you and each of your affiliates, including,
without limitation, the Facility or any other financing in lieu thereof, in each case, in connection with the Acquisition (it
being understood and agreed that the Permitted Financing is not in connection with the Acquisition). If during the Exclusivity
Period, you, the Borrower or any of your or its affiliates enter into a commitment, agreement for, or consummate an Alternate
Financing Transaction, in each case, for which the Commitment Parties (as a group) do not provide such debt financing, Borrower
will pay (or cause to be paid) to each Commitment Party, an amount equal to the interest that would otherwise have accrued and
been due for a one (1) year period (calculated based on the per annum Interest Rate from the Term Sheet applicable to the Facility)
on the aggregate principal amount of such Commitment Party’s Agreed Commitment Amount (the “Alternative Financing
Fee”). For purposes of this paragraph, the WC Facility or any other inventory related financing shall constitute
a “Permitted Financing” and shall not, for any reason, constitute an “Alternate Financing Transaction”.

 

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12.          Escrow
Funding; Escrow Termination. If the Escrow Funding Condition (as defined below) is satisfied, the Commitment
Parties agree to fund an amount equal to the total net proceeds of the Loans (net of the Upfront Fee on the Funding Effective Date) into
the Escrow Account on a date (the date on which such funding occurs, the “Funding Effective Date”), which shall
be a date designated by you, but shall not occur prior to February 21, 2022. If the Conditions Precedent have been satisfied prior to
the Termination Date, the net proceeds of the Loans (which will have been funded net of the Upfront Fees on the Funding Effective Date)
in the Escrow Account shall be distributed to the Borrower on the Closing Date. If the Conditions Precedent have not been satisfied prior
to the Termination Date, the net proceeds of the Loans (which will have been funded net of the Upfront Fees on the Funding Effective Date)
plus the deemed refund of the Upfront Fees under the Fee Letter shall be distributed to the Initial Lenders on the Termination Date (other
than pursuant to clause (c) thereof) in full satisfaction of the Loans (such date, the “Escrow Termination Date”).
For purposes hereof, the “Escrow Funding Condition” shall mean the occurrence of each of the following: (1)
the appointment of an Escrow Agent reasonably satisfactory to the Initial Lenders and the Borrower and (2) the execution and delivery
by the Borrower and the Guarantors of a customary escrow agreement (the “Escrow Agreement”) in form and substance
reasonably satisfactory to the Escrow Agent, the Administrative Agent, the Initial Lenders and the Borrower which provides for: (a) the
creation of an escrow account to hold the net proceeds funded by the Lenders hereunder on the Funding Effective Date (the “Escrow
Account”) and (b) the release of the funds on deposit in the Escrow Account to (x) the Borrower to finance the Transactions
upon receipt by the Escrow Agent of notice delivered by both the Initial Lenders and the Borrower that the Conditions Precedent have been
satisfied or (y) the Initial Lenders on the Escrow Termination Date upon a joint instruction of the Initial Lenders.

 

Notwithstanding
the foregoing, if, for any reason, the Commitment Parties do not fund the Facility into escrow, or if the Escrow Agreement is
not executed and delivered by the parties, then the Commitment Parties hereby agree that their commitments and obligations under
paragraph 1 of this Commitment Letter, and any other obligations of the Commitment Parties hereunder, shall remain in full force
and effect and the funding of the Facility shall occur subject to the Conditions Precedent including the conditions set forth
in Exhibit C.

 

13.          Governing Law; Waiver of Jury Trial; etc. This Commitment Letter, the Term Sheet, and the Fee Letter and the rights
and obligations of the parties hereunder and thereunder shall be governed by, and construed in accordance with, the laws of the
State of New York, together constitute the entire agreement between the parties relating to the subject matter hereof and thereof,
and supersede any previous agreement, written or oral, between the parties with respect to the subject matter hereof and thereof;
provided, however, that: (A) the interpretation of the definition of “Material Adverse Effect” (and whether or not
a “Material Adverse Effect” has occurred) and (B) the determination of whether the Acquisition has been consummated
in accordance with the terms of the Acquisition Agreement shall, in each case, be governed by, and construed and interpreted in
accordance with, the internal laws of the State of Texas without giving effect to any choice or conflict of laws provision or
rule (whether of the State of Texas or any other jurisdiction) that would cause the applicable of laws of any jurisdiction other
than the State of Texas. Each of the parties hereto hereby agrees to waive its respective rights to a jury trial of any claim
or cause of action based upon or arising hereunder or under the Fee Letter or any dealings between them relating to the subject
matter of this Commitment Letter or the Fee Letter or the borrower/lender relationship that is being established. The scope of
this waiver is intended to be all encompassing of any and all disputes that may be filed in any court and that relate to the subject
matter of the Transactions, including contract claims, tort claims, breach of duty claims, and all other common law and statutory
claims. Each party hereto acknowledges that this waiver is a material inducement to enter into a business relationship, that each
has already relied on this waiver in entering into this Commitment Letter and the Fee Letter, and that each will continue to rely
on this waiver in its related future dealings. Each party hereto further warrants and represents that it has reviewed this waiver
with its legal counsel and that it knowingly and voluntarily waives its jury trial rights following consultation with legal counsel.
This waiver is irrevocable, meaning that it may not be modified either orally or in writing (other than by a mutual written waiver
specifically referring to this Section 12 and executed by each of the parties hereto), and this waiver shall apply to any subsequent
amendments, renewals, supplements, or modifications hereto or to the Fee Letter. In addition, with respect to any action or proceeding
arising out of or relating to this Commitment Letter, the Term Sheet, the Fee Letter, the Transactions, or the performance of
any of the parties hereunder, the parties hereto hereby irrevocably: (a) submit to the exclusive jurisdiction of any New York
State or Federal court sitting in the Borough of Manhattan, New York, New York; (b) agree that all claims with respect to such
action or proceeding shall be heard and determined in such New York State or Federal court; (c) waive the defense of any inconvenient
forum to such New York State or Federal court; (d) agree that a final judgment in any such action or proceeding shall be conclusive
and may be enforced in another jurisdiction by suit on the judgment or in any other manner provided by law; and (e) consent to
service of process by mailing or delivering a copy of such process to such party at its address set forth on the first page of
this Commitment Letter and agree that such service shall be effective when sent or delivered. Nothing in this Commitment Letter
shall affect any right that any Commitment Party or any of its affiliates may otherwise have to bring any action or proceeding
relating to this Commitment Letter and the Transactions against you or your properties in the courts of any jurisdiction. 

 

    9 

     

    

 

14.          Amendments; Counterparts; etc. No amendment or waiver of any provision hereof or the Term Sheet, shall be effective unless
in writing and signed by the parties hereto, and no amendment or waiver of any provision of the Fee Letter shall be effective
unless in writing and signed by the applicable parties thereto, and, in each case, then only in the specific instance and for
the specific purpose for which given. This Commitment Letter may be executed in any number of counterparts and by different parties
hereto in separate counterparts, each of which when so executed shall be deemed to be an original and all of which taken together
shall constitute one and the same agreement. Delivery of an executed counterpart of a signature page of this Commitment Letter
by facsimile transmission (or in “pdf” or similar format by electronic mail) shall be effective as delivery of a manually
executed counterpart of this Commitment Letter. Any signature to this Commitment Letter may be delivered by facsimile, electronic
mail (including pdf) or any electronic signature complying with the U.S. federal ESIGN Act of 2000 or the New York Electronic
Signature and Records Act or other transmission method and any counterpart so delivered shall be deemed to have been duly and
validly delivered and be valid and effective for all purposes to the fullest extent permitted by applicable law.

 

15.          PATRIOT Act Notification. We hereby notify you that pursuant to the requirements of the USA PATRIOT Act, Title III of Pub.
L. 107-56 (signed into law October 26, 2001) (as the same may be amended and in effect from time to time, the “PATRIOT
Act”), each Commitment Party is required to obtain, verify, and record information that identifies the Borrower
and the Guarantors, which information includes the name, address, tax identification number, and other information regarding the
Borrower and the Guarantors that will allow the Commitment Parties to identify the Borrower and the Guarantors in accordance with
the PATRIOT Act. This notice is given in accordance with the requirements of the PATRIOT Act and is effective as to each Commitment
Party and each Lender. You hereby acknowledge and agree that the Commitment Parties shall be permitted to share any or all such
information with the Lenders.

 

16.          Expiration Date. If the foregoing proposal is acceptable to you, please so confirm by signing and returning to us executed
counterparts of this Commitment Letter and the Fee Letter. Unless we receive your executed counterparts hereof and thereof by
5:00 p.m., New York City time, on February 18, 2022 (the “Expiration Date”) our offer hereunder will
automatically expire at such time without further action or notice.

 

[Signature
Pages Follow]

 

    10 

     

    

 

We
are pleased to have this opportunity and we look forward to working with you on this transaction. 

 

	 	Very truly
    yours,
	 	 
	 	WHITEBOX
    MULTI-STRATEGY PARTNERS, LP
	 	 	 
	 	By:	/s/
    Daniel
    Altabef 
	 	 	Name:	Daniel
    Altabef
	 	 	Title:	Deputy Chief Compliance
    Officer and Legal Counsel
	 	 
	 	WHITEBOX
    RELATIVE VALUE PARTNERS, LP
	 	 	 
	 	By:	/s/
    Daniel
    Altabef 
	 	 	Name:	Daniel Altabef
	 	 	Title:	Deputy Chief Compliance
    Officer and Legal Counsel
	 	 
	 	WHITEBOX
    GT FUND, LP
	 	 	 
	 	By:	/s/
    Daniel
    Altabef 
	 	 	Name:	Daniel Altabef
	 	 	Title:	Deputy Chief Compliance
    Officer and Legal Counsel
	 	 
	 	PANDORA
    SELECT PARTNERS, LP
	 	 	 
	 	By:	/s/
    Daniel
    Altabef 
	 	 	Name:	Daniel Altabef
	 	 	Title:	Deputy Chief Compliance
    Officer and Legal Counsel

 

[Signature
Page to Vertex Refining Alabama LLC Commitment Letter]

 

     

     

    

 

	 	HIGHBRIDGE
    TACTICAL CREDIT MASTER
    FUND, L.P.,
	 	By:	Highbridge
    Capital Management, LLC,
	 	 	as Trading Manager
    and not in its individual capacity

 

	 	By:	/s/ Jonathan Segal   
	 	Name: 	Jonathan Segal
	 	Title: 	Managing Director, Co-Chief Investment Officer

 

[Signature
Page to Vertex Refining Alabama LLC Commitment Letter]

 

 

     

     

    

 

	 	BLACKROCK
    DIVERSIFIED PRIVATE DEBT
    FUND MASTER LP
	 	By:	BlackRock
    Financial Management, Inc.,
	 	 	its manager

 

	 	By:	/s/
    Zach Viders 
	 	Name:	Zach Viders
	 	Title:	Authorized Signatory 

 

	 	GCO
    II AGGREGATOR 2 L.P.
	 	By:	BlackRock Financial
    Management, Inc.,
	 	 	its manager

 

	 	By:	/s/
    Zach Viders 
	 	Name:	Zach Viders 
	 	Title:	Authorized Signatory 

 

[Signature
Page to Vertex Refining Alabama LLC Commitment Letter]

 

 

     

     

    

 

	 	CHAMBERS
    ENERGY CAPITAL IV, LP
	 	By:	CEC Fund
    IV GP, LLC, its general partner

 

	 	By:	/s/ Robert Hendricks  
	 	Name: 	Robert Hendricks
	 	Title: 	Partner

 

[Signature
Page to Vertex Refining Alabama LLC Commitment Letter]

 

     

     

    

 

	 	CROWDOUT CREDIT OPPORTUNITIES
    FUND LLC
	 	 	
	 	By:	/s/ Alexander Schoenbaum       
	 	Name:	Alexander Schoenbaum
	 	Title:	Managing Member

 

	 	CROWDOUT CAPITAL LLC
	 	 	
	 	By:	/s/ Alexander Schoenbaum       
	 	Name:	Alexander Schoenbaum
	 	Title:	Chief Executive Officer

 

[Signature Page to Vertex Refining Alabama
LLC Commitment Letter]

 

     

     

    

 

Accepted and agreed to as of

the date first written above:

 

	Vertex Refining Alabama LLC	 
	 	 	 
	By:	/s/ Benjamin P. Cowart	 
	 	Name: Benjamin P. Cowart	 
	 	Title: Chief Executive Officer	 

 

	Vertex
ENERGY, INc.	 
	 	 	 
	By:	/s/ Benjamin P. Cowart	 
	 	Name: Benjamin P. Cowart	 
	 	Title: Chief Executive Officer 	 

 

[Signature Page to Vertex Refining Alabama
LLC Commitment Letter]

 

     

     

    

 

Schedule I

 

Agreed Commitment Amounts

 

	Commitment Party	Agreed Commitment Amount
	Whitebox Multi-Strategy Partners, LP	$13,500,000.00
	Whitebox Relative Value Partners, LP	$6,700,000.00
	Whitebox GT Fund, LP	$1,200,000.00
	Pandora Select Partners, LP	$1,100,000.00
	Highbridge Tactical Credit Master Fund, L.P. 	$22,500,000.00
	GCO II Aggregator 2 L.P.	$46,443,724.34
	BlackRock Diversified Private Debt Fund Master LP	$18,556,275.66
	Chambers Energy Capital IV, LP	$7,500,000.00
	CrowdOut Credit Opportunities Fund LLC	$1,000,000.00
	CrowdOut
    Capital LLC	$6,500,000.00
	TOTAL	$125,000,000.00

 

    I-1 

     

    

 

	CONFIDENTIAL	EXHIBIT
    A

 

TERM SHEET

 

EXHIBIT
A 

 

SUMMARY
OF TERMS AND CONDITIONS

 

 

	Borrower:	Vertex
                                         Refining Alabama LLC, a Delaware limited liability company (the “Borrower”
                                         and together with the Guarantors (as defined below), the “Loan Parties”).

 

	Guarantors:	Subject
                                         to exceptions to be agreed, Vertex Energy Inc. (“Parent”) and
                                         all direct and indirect subsidiaries of Parent (the “Subsidiary Guarantors”
                                         and together with Parent (the “Guarantors”); provided that
                                         all Guarantors of the WC Facility (as defined below) and/or convertible senior notes
                                         shall be guarantors of the Facility.

 

	Administrative Agent and Collateral Agent:	Cantor Fitzgerald
    Securities (in such capacity, the “Administrative Agent”).

    

	Lenders:	Certain
funds managed or advised by Whitebox Advisors, LLC, as lenders (“Whitebox”), certain funds managed by Highbridge
Capital Management, LLC, as lenders (“Highbridge”), certain funds and accounts under management by BlackRock
Financial Management, Inc. or its affiliates, as lenders (“BlackRock”), Chambers Energy Capital IV, LP, as
a lender (“Chambers”), CrowdOut Capital LLC, as a lender (“CrowdOut Capital”),
CrowdOut Credit Opportunities Fund LLC, as a lender (“CrowdOut Credit”, and collectively with Whitebox, Highbridge,
BlackRock, Chambers and CrowdOut Capital, the “Initial Lenders”), and a syndicate of other lenders agreed
to by the Borrower and the Initial Lenders (collectively, with the Initial Lenders, the “Lenders”).

 

	Facility:	$125,000,000
                                         first-lien senior secured term loan facility (the “Facility”).

 

	Availability:	The
                                         Facility will be available in a single drawing in U.S. dollars on the Closing Date. Amounts
                                         borrowed under the Facility that are repaid or prepaid may not be reborrowed. Prior to
                                         the Closing Date, the amount of the net proceeds of the loans to be funded to the Borrower
                                         under the Facility shall be deposited into the Escrow Account upon satisfaction or waiver
                                         of the Escrow Funding Condition.

 

	Use of Proceeds:	Proceeds under
    the Facility will be used to fund (i) the purchase of the Mobile Refinery, (ii) the renewable diesel conversion of a portion
    of the Mobile Refinery, (iii) working capital and liquidity needs, and (iv) certain fees and expenses associated with the
    closing of the Facility.

 

	Maturity & Amortization:	The Facility shall mature on the third anniversary of the Closing
    Date (the “Maturity Date”). Beginning on the first anniversary of the Closing Date, the loan will
    amortize in equal quarterly installments in aggregate annual amounts equal to 5.0% of the original principal amount of the
    Facility with the first amortization payment due on the last day of the fifth fiscal quarter ending after the Closing Date,
    and the balance payable on the Maturity Date. All payments of principal and interest to be made in cash in immediately available
    funds.

   

	Guarantees:	The
                                         payment and performance obligations of the Borrower under the Facility (the “Borrower
                                         Obligations”) will be unconditionally guaranteed jointly and severally
                                         on a senior secured basis by the Guarantors.

 

    	 	A-1	 

     

    

 

	Security:	The
                                         Borrower Obligations and the Guarantees will be secured by substantially all of the present
                                         and after-acquired assets of the Loan Parties (collectively, the “Collateral”),
                                         including but not limited to: (a) a perfected first priority pledge of all of the equity
                                         interests owned by each Guarantor (other than certain exceptions to be agreed, and which,
                                         for the avoidance of doubt, shall not include any equity interests issued by Parent),
                                         (b) perfected first priority security interests in, and mortgages on, substantially all
                                         other tangible and intangible assets of the Loan Parties (other than the WCF Priority
                                         Collateral) including but not limited to equipment, general intangibles (including contract
                                         rights), investment property, U.S. intellectual property, owned and leased real property,
                                         instruments, chattel paper and documents, letter of credit rights, commercial tort claims,
                                         and all other property of the Loan Parties and proceeds of the foregoing (collectively,
                                         the “Term Priority Collateral”), and (c) a perfected security
                                         interest in all WCF Priority Collateral (subject to first priority liens granted to the
                                         lenders under the WC Facility), in each case, subject to permitted liens and exceptions
                                         to be agreed. The priority of liens securing the Borrower Obligations and the Guarantees
                                         on one hand and the obligations under the WC Facility on the other hand shall be governed
                                         by an intercreditor agreement in form and substance satisfactory to the Lenders and the
                                         Administrative Agent in their sole discretion.

 

		The
                                         Collateral will be free and clear of other liens, claims, and encumbrances, except permitted
                                         liens and encumbrances acceptable to the Initial Lenders (to be set forth in the Facility
                                         Documentation). Notwithstanding the foregoing, prior to and after the Closing Date, the
                                         Initial Lenders may agree with the Borrower to not require perfection of a security interest
                                         in certain assets if the Initial Lenders reasonably determines that the cost of obtaining
                                         or perfecting such security interest is excessive in relation to the benefit afforded
                                         to the Lenders.

 

		Facility
                                         Documentation to provide mechanics for pari passu liens for any permitted hedge
                                         providers (“Secured Hedge Providers”); provided, that Secured
                                         Hedge Providers shall not have rights with respect to ordinary course management/release
                                         of the Term Priority Collateral permitted under the Facility or separate enforcement
                                         or foreclosure rights other than their ability to terminate their hedges.

 

		“WCF
                                         Priority Collateral” means, with respect to any WC Facility, all: (1) inventory, including crude, feedstock, intermediates and refined products,
(2) accounts receivable, (3) cash margin and deposit accounts containing only (x) proceeds of the foregoing assets and (y) certain mutually
agreed cash or cash equivalents to be held as cash collateral for performance assurance or margin under the WC Facility, (4) any contracts,
documents, general intangibles (but excluding (i) intellectual property, (ii) software, (ii) tax refunds, (iii) partnership interests,
(iv) intercompany indebtedness and (v) unless otherwise related to the assets described in clauses (1) through (3) above, commercial tort
claims), instruments, letter of credit rights, letters of credit, commercial tort claims and supporting obligations, in each case related
to the foregoing assets, (5) books and records related to the foregoing and (6) identifiable proceeds (including insurance policies and
proceeds) of the assets in the foregoing clauses (1) through (6). It is understood and agreed that in no event will the WCF Priority Collateral
include the Escrow Account (or the funds deposited therein) and no security interest in, or lien on the Escrow Account will be granted
in favor of the lenders under the WC Facility.

 

		The
                                         Administrative Agent’s liens and security interests shall be evidenced by documentation
                                         reasonably satisfactory to the Initial Lenders, including search results and collateral
                                         releases from prior lenders in form and substance reasonably satisfactory to the Initial
                                         Lenders.

 

    	 	A-2	 

     

    

 

	Intercreditor
                           Agreements:	The
                                         Initial Lenders shall require an acceptable intercreditor agreement with each creditor
                                         that has a lien on the Collateral (including an intercreditor agreement with the counterparty
                                         to the intermediation arrangements secured by WCF Priority Collateral (such intermediation
                                         arrangements, the “WC Facility” and such intercreditor agreement,
                                         the “Intercreditor Agreement”)), and with each other creditor
                                         providing secured financing to the Loan Parties, in the Initial Lenders’ discretion.

 

	Interest
                           Rate	On and after the Closing,
                                        the loans under the Facility will bear interest at the applicable Base Rate, plus 8.75%
                                        (the “Interest Rate”).

 

	 	“Base
                                         Rate” shall be, for any day, the greater of: (i) the per annum rate publicly
                                         quoted from time to time by The Wall Street Journal as the “Prime Rate” in
                                         the United States1 minus 1.50% as in effect on such day and (ii) the sum of
                                         the Fed Funds rate for such day plus 1/2 of 1%; provided, however, that in no event shall
                                         Base Rate be less than 1.0%.

 

	 	The
                                         Interest Rate on all Loans, other credit extensions, and fees may be increased by 2%
                                         per annum during the existence of an event of default.

 

	Upfront
                                 Fee/Original Issue Discount:	The
                                         Facility will be issued with original discount of 1.50%, inclusive of the Upfront Fee
                                         (as defined in the Fee Letter).

 

	Ticking
                                 Fee:	A
ticking fee (the “Ticking Fee”) equal to 10.50% per annum on the gross aggregate principal amount of the Facility.
The Ticking Fee shall be payable monthly in arrears on the last business day of each calendar month and shall accrue for the period beginning
on and including the earlier of (x) the Funding Effective Date or (y) the date that is 14 days after the date hereof, and terminating
on and including the date on which the funds on deposit in the Escrow Account are released.

     

	Voluntary Prepayments:	Loans
                                         bearing interest based on the Base Rate may be prepaid with same-day written notice,
                                         subject to the applicable Prepayment Premium.

 

	Prepayment
                           Premium:	Usual and customary
                                         for transactions of this type, including the following premium (the “Prepayment
                                         Premium”):

 

		(i)	for
                                         any voluntary prepayments made from the Closing Date through the first 18 months after
                                         the Closing Date, the Borrower shall pay to Lenders a prepayment premium in an amount
                                         equal to (x), one hundred fifty percent (150%) of the then applicable Interest Rate,
                                         multiplied by (y), the amount of such prepayment;

 

		(ii)	for
                                         any voluntary prepayments made in months 19 through 24 after the Closing Date, the Borrower
                                         shall pay to Lenders a prepayment premium in an amount equal to (x), fifty percent (50%)
                                         of the then applicable Interest Rate, multiplied by (y), the amount of such prepayment;
                                         and

 

 

1
Such rate is accessible at https://www.wsj.com/market-data/bonds/moneyrates?mod=md_bond_view_money_rates_full 

    	 	A-3	 

     

    

 

		(iii)	for
                                         any voluntary prepayments made thereafter but prior to the date that is 90 days before
                                         the Maturity Date, the Borrower shall pay to Lenders a prepayment premium in an amount
                                         equal to (x), twenty five percent (25%) of the then applicable Interest Rate, multiplied
                                         by (y), the amount of such prepayment.

 

	 	 	All
                                         principal payments of the loans after an acceleration and all mandatory prepayments (other
                                         than (x) as contemplated in clause (ii) of “Mandatory Prepayments” below
                                         and (y) with respect to the proceeds of the UMO Sale which are addressed in “Mandatory
                                         Prepayments” below), whether before or after an event of default, shall in each
                                         case be accompanied by the applicable Prepayment Premium.

  

	Mandatory
                           Prepayments:	Subject to the
                                         Intercreditor Agreement, 100% of the net proceeds of the following shall be applied as
                                         a prepayment of the outstanding amount of the Facility: (i) any sale or disposition of
                                         any assets (other than sales of inventory in the ordinary course of business, proceeds
                                         derived from Used Motor Oil asset divestitures (each such divestiture, a “UMO
                                         Sale”) (which are addressed below), and other customary exceptions to be
                                         agreed), and subject to reinvestment rights in equipment and sales of obsolete equipment
                                         to be agreed, (ii) casualty insurance and condemnation awards (subject to customary exclusions,
                                         thresholds, reinvestment provisions and other exceptions to be agreed), and (iii) debt
                                         and equity issuances.

 

	 	The
                                         Borrower shall provide prior written notice to the Administrative Agent and Lenders of
                                         any net proceeds from a UMO Sale (to be defined in the Facility Documentation and, in
                                         any event, such definition shall set forth specified assets related to the legacy used
                                         motor oil business) (such proceeds, “UMO Sale Proceeds”). Once
                                         at least $5,000,000 of UMO Sale Proceeds have been received, the Borrower shall offer
                                         to apply fifty percent (50%) of such UMO Sale Proceeds (such amount, the “Required
                                         Amount”) as a repayment on the Facility with such Required Amount subject
                                         to a 1% premium and may, at its election, offer additional amounts above the Required
                                         Amount of such UMO Sale Proceeds (any such additional amount in excess of the Required
                                         Amount, an “Elective Amount”) as a repayment on the Facility
                                         with such Elective Amount instead subject to the Prepayment Premium stated in clauses
                                         (i) through (iii) above. Any Lender may reject any portion of its pro rata share of such
                                         mandatory prepayment, whether the Required Amount or the Elective Amount (“Declined
                                         Proceeds”). Any Declined Proceeds shall (1) first, be applied to prepay
                                         non-declining Lenders’ pro rata share of the outstanding amount of the Facility
                                         (excluding the outstanding amount of the Facility owed to the declining Lenders) and
                                         (2) second, be retained by the Borrower; provided that non-declining Lenders’ may
                                         decline such additional amounts under clause (1) and such amounts will be retained by
                                         the Borrower. If the Borrower elects to voluntarily prepay the outstanding amount of
                                         the Facility with any Declined Proceeds, then such prepayment shall be accompanied with
                                         the applicable Prepayment Premium stated in clauses (i) through (iii) above.

 

	Change
                                 of Control Put:	The Borrower will be required to offer to prepay
                    all outstanding loans under the Facility following the occurrence of a change of control (to be defined in
                    the Facility Documentation) at 101% of the outstanding principal amount thereof.

 

    	 	A-4	 

     

    

 

	Equity
                                 Warrants:	On
the Closing Date, Parent shall issue to the Lenders (or at their option, an affiliate of such Lender or a fund or account managed or
administered by the same entity (or its affiliate) that manages or administers such Lender) (each, a “Warrant Recipient”)
warrants to purchase 2.75 million shares of common stock of the Parent on a pro rata basis based on the Lender’s commitments /
outstanding principal of debt under the Facility (the “Warrants”). The Warrants shall be issued on substantially
the terms and conditions set forth in Exhibit B.

    

	Representations
                                         & Warranties:	Usual
                           and customary representations and warranties for facilities of this type (with materiality qualifiers
                           and exceptions to be agreed).

 

	Conditions
                                         Precedent:	As
set forth in Exhibit C.

 

	Financial
                                         Covenant:	Minimum
                             Consolidated Liquidity. The Loan Parties shall not, at any time, permit Consolidated Liquidity
                             to be less than $12,500,000 for any period of more than three consecutive Business Days (the “Financial
                             Covenant”).

 

	 	“Consolidated
                                         Liquidity” means, at any time, an amount determined for the Loan Parties
                                         on a consolidated basis, equal to the aggregate sum of Unrestricted Cash of the Loan
                                         Parties.

 

	 	“Unrestricted
                                         Cash” means, on any date, the aggregate amount of unrestricted cash and
                                         cash equivalents held in securities accounts or deposit accounts of the Loan Parties,
                                         but only if and to the extent constituting first priority perfected Collateral and in
                                         any event excluding any cash or cash equivalents (x) subject to any lien (other than
                                         certain permitted liens), (y) classified as “restricted cash” or the equivalent
                                         thereof in accordance with GAAP on the consolidated balance sheet of the Loan Parties
                                         or (z) otherwise in any manner restricted for use.

 

	 	The
                                         Facility will include a “most favored nations” provision for maintenance
                                         financial covenants with other indebtedness of the Loan Parties (which would be subject
                                         to agreed upon equity cure provisions to the extent applicable).

 

	Other
                                         Covenants:	Usual
                       and customary covenants for facilities of this type (with materiality thresholds and baskets to be agreed)
                       including but not limited to:

         

		●	Usual
                                         and customary affirmative and operational covenants, including, without limitation, maintenance
                                         of existence, business and properties, payment of taxes, insurance, inspection, formation
                                         and maintenance of subsidiaries, ERISA, compliance with laws (including OFAC, FATCA and
                                         anti-corruption laws), use of proceeds, compliance with contracts and leases, and further
                                         assurances. The Facility will also include operating covenants for the successful conversion
                                         to renewable diesel production, including reasonable evidence of initial commercial production
                                         of renewable diesel by a date certain to be agreed and, provided, that such date may
                                         be automatically extended as a result of certain to be agreed events or conditions.

 

    	 	A-5	 

     

    

 

		●	Usual
                                         and customary negative covenants, including, without limitation, those restricting indebtedness
                                         (including exceptions for capital leases, the WC Facility and certain non-speculative
                                         hedges and guaranties; liens; investments and acquisitions (excepting Mobile Refinery
                                         acquisition); loans and advances; mergers and consolidations; sales of assets (excepting
                                         UMO Sales); prepayments of indebtedness, dividends, stock repurchases and other restricted
                                         payments; use of proceeds; no changes in fiscal year; no changes in nature of business
                                         (except for the conversion of a portion of the Mobile Refinery to renewable diesel);
                                         absence of contractual restrictions; amendments to certain documents; transactions with
                                         affiliates; and activities of the Parent.

 

	Reporting
                           Requirements:	Usual and customary
                                         covenants for facilities of this type including but not limited to:

 

		●	Quarterly
                                         covenant compliance certificates signed by the Parent’s chief financial officer
                                         within 45 days of quarter end for the first three fiscal quarters of each year and with
                                         the annual audited financial statements.

 

		●	If
                                         a default or event of default has occurred and is continuing, monthly company-prepared
                                         consolidated financial statements for the Parent within 30 days of month end.

 

		●	A
                                         copy of the Parent’s operating budget for the following fiscal year no later than
                                         30 days prior to the start of each such fiscal year.

 

		●	Other
                                         information and reports as may be reasonably requested by the Lenders. All reports and
                                         financial statements will be in form and scope reasonably acceptable to the Initial Lenders.

 

		●	Notice
                                         of any change of control, material adverse change, default or event of default, or material
                                         adverse litigation or governmental proceeding.

 

		●	Notice
                                         and copies of material notices and amendments, including any commitment termination,
                                         borrowing block notices, waivers or notices of default or enforcement, relating to any
                                         material indebtedness including the WC Facility.

 

		●	ESG-related
                                         materials reasonably requested by the Lenders, including the BlackRock ESG Questionnaire
                                         within 75 days after the end of each year (in each case, subject to Borrower review of
                                         form).

 

    	 	A-6	 

     

    

 

		●	Lender
                                         meetings at times to be reasonably agreed.

  

	 	Notwithstanding
                                         the foregoing, each Lender shall have the option to only receive publicly available information.

  

	Ratings:	On
                                         a post-closing basis, the Loan Parties shall use commercially reasonably efforts to obtain
                                         and maintain a public rating of the Facility by at least two of the following rating
                                         agencies, S&P, Moody’s and Fitch (but not a specific rating).

 

	Events
                                         of Default:	Usual
                    and customary for facilities of this type (with materiality thresholds and grace periods to be agreed), including
                    but not limited to failure to pay any interest, principal, fees or other amounts when due, default under any
                    covenant or agreement in any loan document, any loan document is repudiated or is no longer in force and effect,
                    inaccurate or false representations or warranties, cross default with other debt agreements (including the
                    WC Facility), insolvency, bankruptcy, ERISA, change of control and unsatisfied judgments.

    

	Assignments
                                         & Participations:	Lenders
                                         will be permitted to make assignments to any persons or entities (other than Disqualified
                                         Institutions) in minimum amounts of $1,000,000. Minimums do not apply to assignments
                                         to another Lender or an affiliate of a Lender or a related fund of a Lender (any such
                                         affiliate or related fund of a Lender, an “Affiliated Lender”)
                                         or to assignments by a Lender of all of its Loans and commitments, and minimums may be
                                         waived with consent of the Administrative Agent and (unless an event of default exists)
                                         the Borrower. Assignments by the Initial Lenders and their respective Affiliated Lenders
                                         of commitments/loans held as of the Closing Date (each a, “Funding Date Commitment/Loan”)
                                         to third party non-affiliates shall be subject to the Right of First Offer below. For
                                         the avoidance of doubt, the Right of First Offer shall not apply to any commitments or
                                         loans acquired by the Initial Lenders or their Affiliated Lenders after the Closing Date
                                         from non-affiliated Lenders.

 

	 	For
                                         purposes hereof, “Disqualified Institutions” shall mean any
                                         person that is (i) designated by the Borrower by written notice delivered to the Initial
                                         Lenders on or prior to the Closing Date or (ii) a competitor of the Borrower or its subsidiaries
                                         that has been identified by the Borrower to the Initial Lenders including affiliates
                                         readily identifiable by name, but excluding any affiliate that is primarily engaged in,
                                         or that advises funds or other investment vehicles that are engaged in, making, purchasing,
                                         holding or otherwise investing in commercial loans, bonds and similar extensions of credit
                                         or securities in the ordinary course and with respect to which the Disqualified Institution
                                         does not, directly or indirectly, possess the power to direct or cause the direction
                                         of the investment policies of such entity.

 

	 	Consents
                                         of the Borrower and the Administrative Agent are required for each assignment, which
                                         consents shall not be unreasonably withheld or delayed, except that the Borrower’s
                                         consent shall not be required during certain specified events of default or in the case
                                         of an assignment to another Lender, an affiliate of a Lender, or a related fund. Administrative
                                         Agent’s consent shall not be required in the case of an assignment under the Facility
                                         to another Lender, an affiliate of such Lender, or a related fund with respect to such
                                         Lender. A $3,500 assignment fee shall be payable to the Administrative Agent for each
                                         assignment other than any assignment to a related fund or an affiliate of a Lender.

 

    	 	A-7	 

     

    

 

	 	Lenders
                                         will also be permitted to sell participations with voting rights limited to significant
                                         matters such as changes in principal amount, fees or interest rates and maturity date.

 

	Right
                                         of First Offer:	Each
                        Initial Lender and its respective Affiliated Lenders (each, a “Lender Group”)
                        may assign up to $4,000,000 (the “Free Trade Amount”) of their Funding Date
                        Commitment/Loan to a third party non-affiliate of such Initial Lender without being subject to the Right
                        of First Offer (as defined below). Assignments by an Initial Lender to an Affiliated Lender or another
                        Initial Lender (or Affiliated Lender thereof) shall also not be subject to the Right of First Offer. Any
                        proposed assignment over the Free Trade Amount by any Initial Lender or an Affiliated Lender to a third
                        party non-affiliate (i.e., not an Initial Lender or an Affiliated Lender thereof) will be subject to the
                        following (the “Right of First Offer”):

     

		1.	Such
                                         Initial Lender (the “Selling Initial Lender”) shall offer the
                                         terms of the proposed assignment, including the principal amount and price (the “Offer”)
                                         to the other two Lender Groups (each, a “Purchasing Initial Lender”);
                                         provided that such Offer shall only be required to be made to a Lender Group if such
                                         Lender Group still holds the Facility.

 

		2.	The
                                         Purchasing Initial Lenders shall have 3 business days to agree to the Offer and, to the
                                         extent such agreement is reached, shall close the purchase within a mutually agreeable
                                         time between the Selling Initial Lender and the Purchasing Initial Lender. If both Lender
                                         Groups accept the Offer or a portion thereof, both will be able to participate on a pro
                                         rata basis. If both Lender Groups decline to purchase the full principal amount of the
                                         Offer or any portion thereof, the Selling Initial Lender will have 30 days to agree on
                                         a trade with a third party buyer with identical terms to the Offer for the same principal
                                         amount offered to the Purchasing Initial Lenders or any portion thereof; provided
                                         that the total consideration received by the assignor from such third party buyer
                                         may be (x) greater than or (y) up to 10% less than, in each case, the total consideration
                                         that would have been received from the Purchasing Initial Lenders under the Offer.

 

	Voting:	Amendments,
                                         waivers and other modifications to the definitive documentation for the Facility shall
                                         require the consent of lenders holding more than 66 2/3% of total commitments / outstanding
                                         principal of debt (“Required Lenders”), except (x) consent
                                         of lenders holding more than 80% of total commitments / outstanding principal of debt
                                         (“Supermajority Lenders”) will be required to (i) subordinate
                                         the lien securing the Facility to any other lien securing any material other indebtedness
                                         for borrowed money except in the case of (1) any indebtedness that is expressly permitted
                                         by the Facility as in effect on the Closing Date to either be senior in right of payment
                                         to the Facility or be secured by a lien that is senior to the lien securing the Facility,
                                         (2) any “debtor-in-possession” facility or (3) any other indebtedness so
                                         long as such indebtedness (and any fees offered in connection therewith) is offered ratably
                                         to all Lenders on the same terms and conditions, and (ii) subordinate any of the Facility
                                         in right of payment (including pursuant to any “waterfall” provision) to
                                         any other indebtedness except in the case of (1) any indebtedness that is expressly permitted
                                         by the Facility as in effect on the Closing Date to either be senior in right of payment
                                         to the Facility or be secured by a lien that is senior to the lien securing the Facility,
                                         (2) any “debtor-in-possession” facility or (3) any other indebtedness so
                                         long as such indebtedness (and any fees offered in connection therewith) is offered ratably
                                         to all Lenders on the same terms and conditions, and (y) 100% of “affected lender”
                                         vote will be required to (i) extend or increase any commitment, (ii) extend, waive, forgive,
                                         defer, extend or postpone the date scheduled for payment of any principal, interest (other
                                         than the waiver of default interest) or fees, (iii) reduce the principal amount of any
                                         loan, rate of interest or fees payable, (iv) release all or substantially all parties
                                         from guaranty obligations, (v) release all or substantially all collateral, (vi) amend
                                         the applicable voting section or the definitions of “Supermajority Lenders”
                                         or “Required Lenders” and (vii) modify the pro rata sharing or payment provisions.
                                         Consent of the Secured Hedge Providers will also be required, to the extent an amendment
                                         or waiver is adverse to such Secured Hedge Provider to alter the ratable treatment of
                                         the obligations arising under any secured hedging agreement resulting in such obligations
                                         being junior in right of payment to principal on the Loans or resulting in obligations
                                         owing to any Secured Hedge Provider becoming unsecured (other than ordinary course releases
                                         of Liens permitted in accordance with the terms of the Facility Documentation). Certain
                                         other consent rights and protections with respect to Secured Hedge Providers to be  mutually
                                         agreed.

 

    	 	A-8	 

     

    

 

	Yield
                                         Protection:	Customary
                    provisions protecting the Lenders in the event of prepayment or failure to borrow (funding indemnity), unavailability
                    of funding, capital adequacy requirements, and increased costs due to changes in law or regulation. Payments
                    to be made free and clear of taxes (subject to customary limitations and exceptions).

  

	Expenses:	The
                                         Borrower shall pay all reasonable and documented out-of-pocket costs and expenses of
                                         the Administrative Agent and Lenders associated with the preparation, due diligence (including
                                         third party expenses) and administration of the Facility and loan documentation, including
                                         without limitation (i) the reasonable and documented legal fees of Sidley Austin LLP,
                                         counsel for the Lender group (and one local counsel in each applicable jurisdiction,
                                         for the Lenders as a group), and (ii) fees and expenses of Clifford Chance LLP, as special
                                         counsel for Blackrock in its capacity as Lender with scope of role and limitations as
                                         agreed by Blackrock and the Borrower, regardless of whether the Facility closes. Costs
                                         and expenses of the Administrative Agent and Lenders, including without limitation their
                                         reasonable and documented legal fees, and costs in connection with any default or event
                                         of default or the enforcement of the loan documents to be reimbursed by the Borrower.

 

	Indemnification:	The
                                         Administrative Agent and Lenders and related parties and agents (the “Indemnified
                                         Parties”) will be indemnified against all losses, liabilities, claims,
                                         damages and expenses (“Losses”) relating to or arising out
                                         of the loan documents, the transactions contemplated hereby or the Borrower’s use
                                         of loan proceeds, including without limitation environmental problems, such indemnity
                                         to include without limitation reasonable attorneys’ fees and settlement costs;
                                         provided that the Loan Parties shall not be required to indemnify any Indemnified Party
                                         for any Losses resulting from such Indemnified Party’s gross negligence or willful
                                         misconduct by such Indemnified Party of its obligations under the loan documents (as
                                         determined by a court of competent jurisdiction in a final, non-appealable decision).

 

    	 	A-9	 

     

    

 

	Governing
                                         Law & Forum:	State
                     of New York & Borough of Manhattan.

 

	Counsel
                                         to Initial Lenders:	Sidley
                                   Austin LLP.

     

	Special
                                         Counsel to  BlackRock:	Clifford
                                         Chance LLP.

 

    	 	A-10	 

     

    

	CONFIDENTIAL	EXHIBIT
B    

 

EXHIBIT
B

SUMMARY
OF TERMS AND CONDITIONS: WARRANTS

 

	Issuer:
    	Vertex
    Energy Inc., a Nevada corporation (the “Company”).
	Investors:
    	Certain
     funds managed or advised by Whitebox Advisors, LLC, as lenders
(“Whitebox”), certain funds managed by Highbridge Capital Management, LLC, as lenders (“Highbridge”),
certain funds and accounts under management by BlackRock Financial Management, Inc. or its affiliates, as lenders (“BlackRock”),
Chambers Energy Capital IV, LP, as a lender (“Chambers”), CrowdOut Capital LLC, as a lender (“CrowdOut
Capital”), CrowdOut Credit Opportunities Fund LLC, as a lender (“CrowdOut Credit”, and collectively
with Whitebox, Highbridge, BlackRock, Chambers and CrowdOut Capital, the “Initial Lenders”), and a syndicate
of other lenders agreed to by Vertex Refining Alabama LLC, a Delaware limited liability company, and the Initial Lenders (collectively,
the “Investors” and each, an “Investor”).
	Issuance:	At
    closing, pursuant to an exemption from registration provided by Section 4(a)(2), and Rule 506 thereunder, of the Securities Act of
    1933, as amended, and subject to the Investors making appropriate and customary representations to the Company, in order for the
    Company to confirm an exemption from registration for such grant, the Company will grant the Investors (or at their option, an affiliate
    of any Investor or a fund or account managed or administered by the same entity (or its affiliate) that manages or administers any
    Investor, subject to applicable securities laws) an aggregate of 2,750,000 warrants (the “Warrants”) on
    a pro rata basis (according to their relative commitments/outstanding principal of debt), with each Warrant entitling the holder
    to purchase shares of the Company’s common stock, par value $0.001 per share (the “Common Stock”)
    (the “Warrant Shares”).  The Warrants shall be freely transferrable, subject to applicable securities
    law restrictions.
	Expiration
    Date:	The Warrants will
    expire on the third (3rd) anniversary of the Closing Date (as defined below).

     

	Exercise
    Price:	The
    exercise price for the Warrants will be $4.50 per share.  
	Settlement:	Cash
    exercise or net share settlement (based on the average of the volume-weighted price per share of the Common Stock for the five (5)
    consecutive full trading days ending on the last full trading day immediately preceding the date that a valid exercise notice is
    delivered), at the option of the holder.  Settlement to occur within two (2) business days (or the standard settlement
    cycle) after the delivery of a valid exercise notice, with customary compensation for buy-ins in the event of a failure to deliver
    the Common Stock within such two (2) business day period. 

    B-1

    	 

    

 

	Anti-Dilution:	If
    at any time there is a change in the number or type of outstanding shares of Common Stock as a result of a reclassification, recapitalization,
    exchange, stock split (including a reverse stock split), combination or readjustment of shares or any stock dividend or stock distributions,
    or the Company makes any rights issuances, other dividends or distributions of assets or property of any kind or issuer tender offers,
    then the exercise price of the Warrants shall be subject to a customary adjustment with respect to any Warrants that are outstanding
    as of such date.  The Warrants shall have “weighted average” price-based anti-dilution protection for issuances
    below exercise price (subject to exceptions for (a) issuances of Common Stock, options or convertible securities to directors, officers
    and employees of and consultants to the Company pursuant to an equity compensation plan approved by the Company’s board, (b)
    issuances of Common Stock upon the exercise of options or convertible securities that were issued prior to the date of issuance of
    the Warrants, provided that the conversion price and number of shares issuable is not modified after the date of issuance of the
    Warrants (except for adjustments resulting from anti-dilution provisions contained in the instruments governing such securities as
    in effect on the date of issuance of the Warrants), (c) issuances of Common Stock via a stock dividend, stock split, reverse stock
    split, reclassification or similar transaction, in each case, which will trigger a proportional adjustment of the Warrants Shares
    under the other provisions of the Warrants, (d) issuances of Common Stock, options or convertible securities as consideration for
    the acquisition of another business and/or related assets (including via merger, reorganization or joint venture) and (e) issuances
    of Common Stock upon the exercise of any of the Warrants).  The exercise price of the Warrants will also be subject to
    customary adjustments for any cash or stock dividends on the Common Stock.
	Registration
    Rights Agreement: 	The Company
    shall use commercially reasonable efforts to (i) file a registration statement with the U.S. Securities and Exchange Commission (the
    “SEC”) covering the resale of the Warrant Shares (as may be reduced by securities sold in a registered
    offering or those sold or saleable pursuant to an exemption from registration without volume or manner-of-sale restrictions, the
    “Registrable Securities”) pursuant to a registration statement under the Securities Act of 1933, as amended
    (the “Securities Act”) (a “Registration Statement”) as soon as reasonably practicable
    and in no event later than seventy-five (75) days of the Closing Date; (ii) in the event such Registration Statement is not automatically
    effective upon the filing thereof, have such Registration Statement declared effective as promptly as practicable thereafter and
    in any case within forty-five (45) days following the filing thereof (or seventy-five (75) days if the SEC reviews the Registration
    Statement); and (iii) maintain the effectiveness of the Registration Statement until the earlier of all securities registered thereby
    ceasing to constitute Registrable Securities or the third anniversary of the effective date of the Registration Statement. A failure
    to achieve any of (i), (ii) or (iii) (each, a “Registration Default”) shall cause the Company to pay customary
    liquidated damages to the Investors in the amount of 1% of the fair value of the Registrable Securities then held by them upon the
    occurrence of such Registration Default, and 1% of such amount thereafter, each month that such Registration Default continues, up
    to a maximum of 10% of such amount in aggregate.

     

    B-2

    	 

    

 

	  	

    To the
    extent that the Company is permitted to file a shelf registration statement pursuant to Rule 415 under the Securities Act (a “Shelf
    Registration Statement”) at the time the filing of the Registration Statement is required as set forth above, the Company
    shall be obligated to file a Shelf Registration Statement covering all Registrable Securities held by the Investors at such time
    in lieu of the Registration Statement; if the Company is ineligible to file a Shelf Registration Statement at such time, it shall
    be obligated to register such number of Registrable Securities as the Investors shall request on such registration form as it is
    eligible to use at such time.

     

    The Company
    shall facilitate underwritten offerings pursuant to such Shelf Registration Statement at the Investors’ request and to the
    extent lawful (provided, that the requesting Investors reasonably expect aggregate gross proceeds in excess of $35,000,000),
    shall pay out-of-pocket-expenses (including registration fees, reasonable and documented fees of one counsel for the participating
    Investors (as a group) and reasonable and documented auditors fees, but excluding underwriter’s commission, which shall be
    paid from the proceeds of such underwritten offering) related to such registration and offering.

     

    The
    Company shall use commercially reasonable efforts to timely file all reports required to be filed by the Company after the date hereof
    pursuant to the Securities Exchange Act of 1934, as amended (the “Exchange Act”). If the Company is not
    required to file reports pursuant to the Exchange Act prior to the time when the Warrant Shares cease to be Registrable Securities,
    the Company will prepare and furnish to the Investors and make publicly available in accordance with Rule 144(c) such information
    as is required for the Investors to sell the Warrant Shares under Rule 144.

     

    The
    Investors shall also be entitled to customary “piggyback” rights as to any offerings of shares of Common Stock effected
    by the Company, subject to customary cutbacks (“Piggyback Registration”). All expenses of the Registration
    Statement, Shelf Registration Statement and Piggyback Registration shall be paid by the Company (including reasonable and documented
    legal expenses of one counsel for the participating Investors (as a group)) other than discounts and commissions to be paid to the
    underwriters of any such offering, brokerage or similar fees, and applicable taxes. Investors shall be required to agree to
    customary terms and conditions of any Piggyback Registration in which they participate, including underwriting and lockup
    arrangements to be negotiated with any underwriters therefor (if any), and shall provide any required information for a Registration
    Statement or a Piggyback Registration in order to participate therein.

 

    B-3

    	 

    

 

	 	Such
    registration rights shall be set forth in a registration rights agreement that contains the foregoing provisions and other customary
    terms and conditions, including indemnification provisions customary for transactions of this type.

                                                          

	Beneficial
    Ownership:	Notwithstanding
    anything herein to the contrary, the Warrants shall not be exercisable to the extent that following such exercise, the holder thereof
    (or any person whose beneficial ownership of Common Stock is aggregated with such holder’s beneficial ownership of Common Stock),
    would become the beneficial owner of more than 4.9 or 9.9% (at such holder’s election on the Closing Date which election may
    be changed on 61 days written notice) of the outstanding shares of Common Stock. The term “beneficial owner” shall have
    the meaning set forth in Section 13(d) of the Securities Act.

     

	Fundamental
    Transactions:	The Warrants
    shall survive Fundamental Transactions irrespective of any exercise limitations then in effect in connection therewith on customary
    terms and shall be required (to the extent the Warrants are not repurchased pursuant to the Put Right or the Call Right described
    below) to be assumed by the successor entity as applicable in any such Fundamental Transaction; provided that in connection with
    any such Fundamental Transaction the Company shall provide written notice (“Fundamental Transaction Notice”)
    of a Fundamental Transaction to all holders of outstanding Warrants reasonably promptly after public announcement thereof (and, in
    any event, not less than thirty (30) days prior to the consummation of such Fundamental Transaction) and (a) the holder of a Warrant
    shall have the right (the “Put Right”) to require the Company to repurchase the Warrants held by such holder
    by delivering notice to the Company (the “Put Notice”) at any time after the holder’s receipt of
    a Fundamental Transaction Notice, but prior to the third (3rd) business day before consummation of the Fundamental Transaction and
    (b) the Company shall have the right (the “Call Right”) to repurchase the Warrants from all holders thereof
    by delivering notice to such holders (the “Call Notice”) at any time on or after the fifteenth (15th) day
    following the giving of a Fundamental Transaction Notice to all holders of outstanding Warrants, but prior to the third (3rd) business
    day before consummation of the Fundamental Transaction, in each case, for an amount equivalent to the aggregate value, as determined
    by the Black-Scholes Value, of the Warrants held by such holder on the effective date of such Fundamental Transaction. Any such repurchase
    shall occur concurrently with and shall be subject to the consummation of such Fundamental Transaction.

    “Fundamental
    Transaction” shall mean any of the following transactions, whether effected directly or indirectly in one or a series
    of related transactions: (i) any merger or consolidation of the Company with or into another person, (ii) any sale, lease, license,
    assignment, transfer, conveyance or other disposition of all or substantially all of the assets of the Company and its subsidiaries,
    (iii) the consummation of any purchase offer, tender offer or exchange offer (whether by the Company or another person) pursuant
    to which holders of Common Stock are permitted to sell, tender or exchange their shares for other securities, cash or property, (iv)
    any reclassification, reorganization or recapitalization of the Common Stock of the Company or any compulsory share exchange by the
    Company pursuant to which the Common Stock is effectively converted into or exchanged for other securities, cash or property and
    (v) the consummation of a stock or share purchase agreement or other business combination (including, without limitation, a reorganization,
    recapitalization, spin-off, merger or scheme of arrangement) with another person or group of persons. provided, however, only
    those transactions described in subparagraphs (i), (iii), (iv) and (v) that result in (a) a person or group becoming beneficial owners
    of a majority of the outstanding Common Stock or (b) the holders of the Company’s outstanding Common Stock as of immediately
    before the transaction (or series of related transactions) beneficially owning less than a majority by voting power of the outstanding
    shares of the surviving or successor entity as of immediately after the transaction, shall be considered a Fundamental Transaction
    for purposes of the Put Right and Call Right.

     

    B-4

    	 

    

 

	 	

“Black-Scholes
    Value” shall mean the value of the unexercised portion of a Warrant remaining on the date that the Put Notice or Call
    Notice is delivered, which value is calculated using the Black Scholes Option Pricing Model obtained from the “OV” function
    on Bloomberg utilizing (i) an underlying price per share equal to the greater of (1) the highest closing sale price of the Common
    Stock during the period beginning on the trading day immediately preceding the announcement of the applicable Fundamental Transaction
    (or the consummation of the applicable Fundamental Transaction, if earlier) and ending on the trading day that the Put Notice or
    Call Notice is delivered and (2) the sum of the price per share being offered in cash in the applicable Fundamental Transaction (if
    any) plus the value of the non-cash consideration being offered in the applicable Fundamental Transaction (if any), (ii) a strike
    price equal to the exercise price in effect on the date that the Put Notice or Call Notice is delivered, (iii) a risk-free interest
    rate corresponding to the U.S. Treasury rate for a period equal to the greater of (1) the remaining term of the Warrant as of the
    date that the Put Notice or Call Notice is delivered and (2) the remaining term of the Warrant as of the date of consummation of
    the applicable Fundamental Transaction or as of the date that the Put Notice or Call Notice is delivered if such notice is delivered
    prior to the date of the consummation of the applicable Fundamental Transaction, (iv) a zero cost of borrow and (v) an expected volatility
    equal to the 90 day volatility obtained from the “HVT” function on Bloomberg (determined utilizing a 365 day annualization
    factor) as of the trading day immediately following the earliest to occur of (A) the public disclosure of the applicable Fundamental
    Transaction, (B) the consummation of the applicable Fundamental Transaction and (C) in the case of the exercise of a Put Right, the
    date on which the applicable holder was first notified by the Company of the applicable Fundamental Transaction.

	Closing
    Date:	The later of the
    date of execution and delivery of definitive documentation governing the $125,000,000 first-lien senior secured term loan facility
    described in Exhibit A and consummation of the transactions contemplated by such documentation.

     

    B-5

    	 

    

 

	No
    Rights as Stockholders:	Holders of Warrants
    shall have no rights as stockholders of the Company (including voting rights) unless such Warrants are exercised into Common Stock.

     

	Warrant
    Agreement:	The Warrants will
    be subject to a Warrant Agreement (the “Warrant Agreement”) with a third party warrant agent reasonably
    acceptable to the Investors, whose fees and expenses shall be paid for by the Company, setting forth the applicable terms described
    herein and other customary terms and conditions as may be agreed by the Company and the Initial Lenders.

     

    Amendments, waivers
    and other modifications to the Warrant Agreement and the Warrants shall require the consent of holders holding more than 66 2/3%
    of the Warrants; provided that the consent of each affected holder shall be required for amendments to certain customary provisions,
    including amendments that would (i) increase the exercise price or decrease the number of Warrant Shares receivable upon exercise
    of the Warrants (other than in connection with the anti-dilution provisions); (ii) accelerate the expiration date; or (iii) modify
    the anti-dilution provisions in a manner adverse to the holders.

     

	Governing
    Law:	The definitive
    documentation entered into in connection with the granting of the Warrants will be governed by, and construed in accordance with,
    the laws of the State of New York.

    This Summary
    of Terms shall be governed by, and construed in accordance with, the laws of the State of New York.

 

    B-6

     

    

 

	CONFIDENTIAL	EXHIBIT C 

 

Project Vulcan II

Summary of Additional Conditions Precedent

 

Capitalized terms used but
not defined in this Exhibit C shall have the meanings set forth in the Commitment Letter to which this Exhibit C is attached and the
other Exhibits to the Commitment Letter. In the case of any such capitalized term that is subject to multiple and differing
definitions, the appropriate meaning thereof in this Exhibit C shall be determined by reference to the context in which it is
used.

 

The
funding of the initial borrowings under the Facility shall be subject to the satisfaction of the following conditions precedent
prior to the Termination Date:

 

1.                 
 

 

(a)          The execution and delivery by the Borrower and the Guarantors of the Facility Documentation consistent with the Term Sheet
and the Commitment Letter (including, without limitation the security agreements), in form and substance reasonably satisfactory
to the Commitment Parties.

 

(b)          The execution and delivery by the Borrower of a customary certificate attesting to the solvency of the Borrower and its
subsidiaries on the Closing Date on a consolidated basis in the form attached as Annex I hereto.

 

2.            The execution and delivery by the Borrowers and the Guarantors of (i) a definitive inventory intermediation agreement, or
similar agreement with respect to the feedstocks, refined products, and other hydrocarbons produced or utilized by the refinery
(the “WCF Agreement”) and (ii) a definitive guarantee and security agreement (the “WCF GSA”),
together with other collateral documents required under the terms of the WCF GSA, and the consummation of all Closing Date transactions
contemplated thereby.

 

3.            The execution and delivery by the agent and/or lenders under the WCF Agreement and any other material permitted secured
indebtedness of the Loan Parties of a definitive intercreditor agreement (the “Intercreditor Agreement”)
in form and substance reasonably satisfactory to the Commitment Parties.

 

4.            The issuance of the Warrants in form and substance satisfactory to the Commitment Parties.

 

5.            The Acquisition shall have been consummated substantially simultaneously with the initial borrowings under the Facility
in accordance with the Acquisition Agreement (and no provision of the Acquisition Agreement shall have been waived, amended, supplemented,
or otherwise modified (including any consents thereunder) in a manner materially adverse to the Lenders without the consent of
the Commitment Parties (such consent not to be unreasonably withheld, delayed, or conditioned)) (it being understood that (i) any
increase in the consideration for the Acquisition shall not be deemed to be materially adverse to the interests of the Lenders
so long as such increase in consideration (x) is pursuant to any purchase price or similar adjustment provisions set forth in the
Acquisition Agreement as of the date hereof and (y) is not funded with additional indebtedness, (ii) any reduction in the purchase
price consideration of 25% or less shall be deemed not to be materially adverse to the Lenders so long as such reduction (x) is
pursuant to any purchase price or similar adjustment provisions set forth in the Acquisition Agreement as of the date hereof
and (y) is allocated to the Facility and the WC Facility, subject to the priorities set forth in the Intercreditor Agreement, as
applicable, (iii) any consent, waiver, amendment, supplement, or other modification in respect of the third party beneficiary rights
applicable to the Administrative Agent, the Commitment Parties or the Lenders or in the governing law without the prior written
consent of the Commitment Parties shall be deemed to be materially adverse to the interests of the Lenders, and (iv) any consent,
waiver, amendment, supplement, or other modification to the definition of “Material Adverse Effect” without the prior
written consent of the Commitment Parties shall be deemed to be materially adverse to the interests of the Lenders.

 

    C-I-1 

     

    

 

6.            The Administrative Agent shall have received, subject to the Intercreditor
Agreement, all documents and instruments required to create and perfect the Administrative Agent’s security interest in the Collateral;
provided however that it is understood and agreed that the Loan Parties shall use commercially reasonable efforts to deliver any required
mortgages, control agreements and certificate of title collateral and other Collateral not perfected by filing UCC-1 financing statements,
or stock certificates by the Closing Date and any such mortgages, control agreement and certificate of title collateral and other Collateral
not perfected by filing UCC-1 financing statements or stock certificates, not so delivered shall be permitted to be delivered no later
than 30 days after the Closing Date (or such longer period as the Administrative Agent and the Required Lenders may agree in their sole
discretion); provided further that any leasehold mortgages or mortgages on other immaterial real property, mortgages with respect thereto
shall be permitted to be delivered on or before a mutually agreeable date after the Closing Date and shall not be subject to such 30 day
requirement. For the avoidance of doubt, the Loan Parties shall have provided all UCC-1 financing statements and intellectual property
filings in form for filing and shall have delivered all certificated pledged equity and documented pledged debt (if any) with appropriate
transfer powers and/or allonges by the Closing Date.

 

7.            The Administrative Agent shall have received customary legal opinions,
organizational documents, customary evidence of authorization, customary officers’ certificates, and customary insurance certificates
and endorsements; provided however that it is understood and agreed that the Loan Parties shall use commercially reasonable efforts to
deliver customary insurance endorsements by the Closing Date and any customary insurance endorsements not so delivered shall be delivered
no later than five (5) Business Days after the Closing Date (or such longer period as the Administrative Agent and the Required Lenders
may agree in their sole discretion).

 

8.            The Borrower and each of the Guarantors shall have provided no less than three (3) business days prior to the Funding Effective
Date the documentation and other information to the Lenders that are reasonably requested by the Lenders to the extent requested
no later than ten (10) business days prior to the Funding Effective Date under the applicable “know-your-customer”
rules and regulations, including, without limitation, the PATRIOT Act.

 

9.                 
 

 

(a)          All accrued costs and expenses (including, without limitation, reasonable and documented legal fees and out-of-pocket expenses)
and other compensation due and payable to the Administrative Agent, and the Initial Lenders and required by the Commitment Letter
or the Fee Letter to be paid on the Funding Effective Date shall have been paid.

 

(b)          All accrued costs, fees, and expenses (including, without limitation, reasonable and documented legal fees and out-of-pocket
expenses) and other compensation due and payable to the Administrative Agent, and the Initial Lenders and required by the Commitment
Letter or the Fee Letter to be paid on the Closing Date shall have been paid (provided that the foregoing amounts may, at
the Borrower’s option, be offset against the proceeds of the Facility funded on the Closing Date).

 

10.          The representations and warranties of the Borrowers and Guarantors contained in the Facility Documentation shall be true
and correct in all material respects (except that such materiality qualifier shall not be applicable to any representations and
warranties that are already qualified or modified by materiality in the text thereof) on the Funding Effective Date.

 

11.          Since the date of the Acquisition Agreement, there shall not have occurred a Material Adverse Effect (as defined in the
Acquisition Agreement).

 

    C-I-2 

     

    

 

12.          The Administrative Agent shall have received (i) unaudited consolidated balance sheets and related statements of operations,
comprehensive income (loss), equity and cash flows of the Borrower and its subsidiaries, for the quarter ending December 31, 2021
and each subsequent fiscal quarter ended at least 45 days before the Funding Effective Date (subject in the case of this clause
(i), to normal and recurring year-end adjustments and the absence of notes) and (ii) the unaudited pro forma consolidated
balance sheet and a related unaudited pro forma consolidated statements of operations and comprehensive income (loss) of
the Borrower and its subsidiaries as of and for the twelve-month period ending on the last day of the most recently completed four-fiscal
quarter period (or, if the end of the most recently completed four-fiscal quarter period of the Borrower is the end of a fiscal
year of the Borrower, ended at least 90 days before the Funding Effective Date), for which financial statements are available pursuant
to clause (i) above prepared after giving effect to the Acquisition as if the Acquisition had occurred as of such date (in the
case of such balance sheet) or at the beginning of such period (in the case of such statement of operations and comprehensive income
(loss)), in each case, which need not be prepared in compliance with Regulation S-X of the Securities Act of 1933, as amended,
or include adjustments for purchase accounting (including adjustments of the type contemplated by Financial Accounting Standards
Board Accounting Standards Codification 805, Business Combinations (formerly SFAS 141R)).

 

13.          The execution and delivery by the Borrower of a customary notice of borrowing.

 

14.          The delivery by the Borrower of funds flow, including sources and uses of the proceeds of the Facility, which shall be in
form and substance reasonably satisfactory to the Commitment Parties.

 

15.          There shall be no order, injunction or decree of any governmental authority restraining or prohibiting the funding under
the Facility and upon the Closing Date, challenging or enjoining the Acquisition. All consents and approvals necessary in connection
with the execution, delivery and performance of the Facility Documentation being executed upon such date have been obtained and
are in full force and effect.

 

16.          No Default or Event of Default has occurred and is continuing.

 

17.          The Initial Lenders shall have completed confirmatory diligence of the Borrower, the Guarantors, and the Target Assets,
limited to corporate organization and capitalization, review of lien searches, review of material contracts and material pending
litigation and no changes or developments shall have occurred, and no new or additional information, shall have been received or
discovered by the Administrative Agent regarding the Borrower or the Guarantors or the transactions contemplated hereby after the
date of the Commitment Letter that either individually or in the aggregate, would reasonably be expected to have a material adverse
effect on the Borrower, the Guarantors or the Facility or any other aspect of the transactions contemplated hereby.

 

18.          Concurrently
with the consummation of the Acquisition, the Loan Parties (and/or the working capital provider) shall execute and deliver or
confirm effectiveness of the material supply and offtake agreements with Shell, Idemitsu and Bunker One on substantially similar
terms as the agreements provided to counsel to the Lenders on February 16, 2022, subject to (x) any
amendments, modifications or adjustments to the terms thereof (other than economic terms) required by
the working capital provider, the Loan Parties or the applicable counterparty to the intermediation arrangements to the extent not
materially adverse to the Lenders and (y) any amendments, modifications or adjustments to the economic
terms thereof required by the working capital provider, the Loan Parties or the applicable counterparty to the intermediation
arrangements to the extent not adverse to the Lenders.

 

The “Closing Date”
shall mean the date, which date must occur before the Termination Date, upon which the conditions set forth in this Exhibit C  have
been satisfied or waived (the forgoing conditions, the “Conditions Precedent”).

 

    C-I-3 

     

    

 

	CONFIDENTIAL	ANNEX I TO EXHIBIT C

 

FORM OF

 

SOLVENCY CERTIFICATE

 

[            ], 2022

 

This Solvency Certificate
is delivered pursuant to Section [           ] of the Loan and Security Agreement dated as of [            ], 2022, among [            ] (the “Loan
Agreement”). Capitalized terms used herein and not otherwise defined herein shall have the meanings assigned to such
terms in the Loan Agreement.

 

The undersigned hereby
certifies, solely in his capacity as an officer of Parent and not in his individual capacity, as follows:

 

1.          I am the [Chief Financial Officer] of Parent. I am familiar with the Transactions, and have reviewed the Loan Agreement,
financial statements referred to in Section [    ] of the Loan Agreement and such documents and made such investigation as I have
deemed relevant for the purposes of this Solvency Certificate.

 

2.          As of the date hereof, immediately after giving effect to the consummation of the Transactions
(including the making of Loans under the Loan Agreement and other amounts incurred on the date hereof and the use of proceeds thereof),
on and as of such date (a) (i) the sum of the debt (including contingent liabilities existing as of the date hereof) of Parent
and its Subsidiaries (on a consolidated basis) does not exceed the present fair saleable value of the present assets of Parent
and its Subsidiaries (on a consolidated basis), (ii) the capital of Parent and its Subsidiaries (on a consolidated basis)
is not unreasonably small in relation to its business as contemplated on the Closing Date, and (iii) Parent and its Subsidiaries
have not incurred and do not intend to incur, or believe (nor should they reasonably believe) that they will incur, debts beyond
their ability to pay such debts as they mature or, in the case of contingent liabilities, otherwise become payable and (b) Parent
and its Subsidiaries (on a consolidated basis) are “solvent” within the meaning given that term and similar terms under
applicable laws relating to fraudulent transfers and conveyances. For purposes of the foregoing, the amount of any contingent liability
at any time shall be computed as the amount that, in light of all of the facts and circumstances existing at such time, represents
the amount that can reasonably be expected to become an actual or matured liability (irrespective of whether such contingent liabilities
meet the criteria for accrual under Statement of Financial Accounting Standard No. 5).

 

3.          This Solvency Certificate is being delivered by the undersigned officer only in his capacity as [Chief Financial Officer]
of Parent and not individually and the undersigned shall have no personal liability to the Administrative Agent or the Lenders
with respect thereto.

 

[Remainder of Page Intentionally Left
Blank]

 

    C-I-4 

     

    

 

IN WITNESS WHEREOF,
the undersigned has executed this Solvency Certificate on the date first written above.

 

	 	[                                                     ]
	 	 
	 	By:	 
	 	 	 
	 	 	
        Name:

         

        Title:[Chief Financial Officer] 

 

    C-I-5EX-4.2

 Exhibit 4.2 

Execution Version 

OFFICER’S CERTIFICATE 

OF 
 AMGEN INC. 

Dated as of February 22, 2022 
 The undersigned
officer of the Company certifies, pursuant to resolutions duly adopted by the Board of Directors at a meeting duly held on February 16, 2022 (the “Resolutions”), and in accordance with Sections 2.1, 2.2 and 2.3 of the Indenture,
dated as of May 22, 2014 (the “Indenture”; capitalized terms used herein and not otherwise defined shall have the meanings given to them in the Indenture), between Amgen Inc., a Delaware corporation (the “Company”),
and The Bank of New York Mellon Trust Company, N.A., as trustee (the “Trustee”), the following matters related to the issuance of the Company’s 3.000% Senior Notes due 2029 (the “2029 Notes”), 3.350%
Senior Notes due 2032 (the “2032 Notes”), 4.200% Senior Notes due 2052 (the “2052 Notes”), and 4.400% Senior Notes due 2062 (the “2062 Notes” and, together with the 2029 Notes, the 2032 Notes and
the 2052 Notes, the “Notes”): 
 1. Attached hereto as Annex A is a true and correct copy of a specimen note (the
“Form of 2029 Note”) representing the 2029 Notes, attached hereto as Annex B is a true and correct copy of a specimen note (the “Form of 2032 Note”) representing the 2032 Notes, attached hereto as Annex
C is a true and correct copy of a specimen note (the “Form of 2052 Note”) representing the 2052 Notes and attached hereto as Annex D is a true and correct copy of a specimen note (the “Form of 2062 Note”)
representing the 2062 Notes. The Form of 2029 Note, the Form of 2032 Note, the Form of 2052 Note and the Form of 2062 Note are herein collectively referred to as the “Forms of Notes.” The Forms of Notes set forth certain of the
terms required to be set forth in this Certificate pursuant to Section 2.2 of the Indenture, and said terms are incorporated herein by reference. The 2029 Notes, the 2032 Notes, the 2052 Notes and the 2062 Notes are each a separate series of
Securities under the Indenture. 
 2. The title of the 2029 Notes shall be the “3.000% Senior Notes due 2029,” the title of the
2032 Notes shall be the “3.350% Senior Notes due 2032,” the title of the 2052 Notes shall be the “4.200% Senior Notes due 2052,” and the title of the 2062 Notes shall be the “4.400% Senior Notes due 2062.” 

3. The 2029 Notes shall be issued at the initial offering price of 99.687% of the principal amount, the 2032 Notes shall be issued at the
initial offering price of 99.756% of the principal amount, the 2052 Notes shall be issued at the initial offering price of 99.442% of the principal amount and the 2062 Notes shall be issued at the initial offering price of 99.384% of the principal
amount. 
 4. The Company will initially issue $750,000,000 aggregate principal amount of the 2029 Notes, $1,000,000,000 aggregate principal
amount of the 2032 Notes, $1,000,000,000 aggregate principal amount of the 2052 Notes and $1,250,000,000 aggregate principal amount of the 2062 Notes (in each case except for Notes authenticated and delivered upon registration of transfer of, in
exchange for, or in lieu of, other Notes pursuant to Sections 2.7, 2.8, 2.11, 3.6 or 9.6 of the Indenture). The Company may issue additional 2029 Notes, 2032 Notes, 2052 Notes and/or 2062 Notes from time to time after the date hereof, and such Notes
will be treated as part of the respective series of Notes for all purposes under the Indenture. 
  

 5. The Notes shall be issued as Global Securities only and will be exchangeable for
certificated notes (“Certificated Notes”) only if: 
  

	 	(a)	 DTC (x) notifies the Company that it is unwilling or unable to continue as depository for the Global
Securities or (y) at any time has ceased to be a clearing agency registered under the Exchange Act at a time when it is required to be registered and, in either case, the Company fails to appoint a successor depository registered as a clearing
agency under the Exchange Act within 90 days of notification to the Company or the Company becoming aware of DTC’s ceasing to be so registered, as the case may be; 

 

	 	(b)	 the Company, at its option, notifies the Trustee in writing to the effect that the Company elects to cause the
issuance of the Certificated Notes; or 

  

	 	(c)	 there has occurred and is continuing an Event of Default with respect to the Notes. 

Certificated Notes delivered in exchange for any Global Security or beneficial interests in Global Securities will be registered in the names,
and issued in any approved denominations, requested by or on behalf of the depository (in accordance with its customary procedures). 
 6.
The Notes shall be denominated in Dollars and payments of principal and interest shall be made in Dollars. 
 7. In addition to the
provisions set forth in Article IV of the Indenture, the following additional provisions shall apply to the Notes and shall be incorporated into the Indenture with respect to the Notes: 

Section 4.5 Change of Control Offer 

(a) If a Change of Control Triggering Event occurs, unless the Company has exercised its option to redeem the Notes as described in
Section 5 of the Security, the Company will be required to make an offer (the “Change of Control Offer”) to each Holder to repurchase all or any part (equal to $2,000 or an integral multiple of $1,000 in excess thereof) of that
Holder’s Notes on the terms set forth in such Security. In the Change of Control Offer, the Company shall be required to offer payment in cash equal to 101% of the aggregate principal amount of Notes repurchased, plus accrued and unpaid
interest, if any, on the Notes repurchased to the date of repurchase (the “Change of Control Payment”). Within 30 days following any Change of Control Triggering Event, a notice will be provided to Holders describing the transaction
that constitutes the Change of Control Triggering Event and offering to repurchase the Notes on the date specified in the notice, which date will be no earlier than 30 days and no later than 60 days from the date such notice is provided (the
“Change of Control Payment Date”); provided, however, that in no event will the Change of Control Payment Date occur prior to the date 90 days following the First Issue Date. 

  
 2 

 (b) On the Change of Control Payment Date, the Company shall, to the extent lawful: 

 

	 	(i)	 accept for payment all Notes or portions of Notes properly tendered pursuant to the Change of Control Offer;

  

	 	(ii)	 deposit with the Paying Agent an amount equal to the Change of Control Payment in respect of all Notes or
portions of Notes properly tendered; and 

  

	 	(iii)	 deliver or cause to be delivered to the Trustee the Notes properly accepted together with an Officer’s
Certificate stating the aggregate principal amount of Notes or portions of Notes being repurchased. 

 (c) Notwithstanding
the foregoing, the Company shall not repurchase any Notes if there has occurred and is continuing on the Change of Control Payment Date an Event of Default under the Indenture, other than a Default in the payment of the Change of Control Payment
upon a Change of Control Triggering Event. 
 (d) The Company will comply with the requirements of Rule 14e-1 under the Exchange Act and any
other securities laws and regulations thereunder to the extent those laws and regulations are applicable in connection with the repurchase of the Notes as a result of a Change of Control Triggering Event. To the extent that the provisions of any
such securities laws or regulations conflict with the Change of Control Offer provisions of the Notes, the Company will comply with those securities laws and regulations and will not be deemed to have breached its obligations under the Change of
Control Offer provisions of the Notes by virtue of any such conflict. 
 (e) If holders of not less than 90% in aggregate principal amount of
the outstanding Notes of the applicable series validly tender and do not withdraw such Notes in a Change Of Control Offer and the Company, or any third party making such an offer in lieu of the Company, purchases all of the Notes validly tendered
and not withdrawn by such holders, the Company or such third party will have the right, upon not less than 10 days nor more than 60 days’ prior notice, provided that such notice is given not more than 30 days following such repurchase pursuant
to the Change Of Control Offer described above, to redeem all Notes that remain outstanding following such purchase on a date specified in such notice (the “Second Change Of Control Payment Date”) and at a price in cash equal to
101% of the aggregate principal amount of Notes repurchased plus any accrued and unpaid interest on the Notes repurchased to, but not including, the Second Change Of Control Payment Date. 

(f) For the purposes of this Section 4.5 only, the following definitions shall apply: 

“Beneficial Owner” shall be determined in accordance with Rules 13d-3 and 13d-5 under the Exchange Act or any successor
provisions, except that a Person will be deemed to have beneficial ownership of all shares that Person has the right to acquire irrespective of whether that right is exercisable immediately or only after the passage of time. 

  
 3 

 “Change of Control” means the occurrence of any of the following:
(1) the consummation of any transaction (including, without limitation, any merger or consolidation) the result of which is that any Person or Group (other than the Company or one of its Subsidiaries) becomes the Beneficial Owner, directly or
indirectly, of more than 50% of the Company’s Voting Stock or other Voting Stock into which the Company’s Voting Stock is reclassified, consolidated, exchanged or changed, measured by voting power rather than number of shares;
provided, however, that a Person shall not be deemed Beneficial Owner of, or to own beneficially, (A) any securities tendered pursuant to a tender or exchange offer made by or on behalf of such Person or any of such Person’s
affiliates until such tendered securities are accepted for purchase or exchange thereunder, or (B) any securities if such beneficial ownership (i) arises solely as a result of a revocable proxy delivered in response to a proxy or consent
solicitation made pursuant to the applicable rules and regulations under the Exchange Act, and (ii) is not also then reportable on Schedule 13D (or any successor schedule) under the Exchange Act; (2) the direct or indirect sale, transfer,
conveyance or other disposition (other than by way of merger or consolidation), in one or more series of related transactions, of all or substantially all of the Company’s assets and the assets of the Company’s Subsidiaries, taken as a
whole, to one or more Persons or Groups (other than the Company or one of its Subsidiaries); provided that none of the circumstances in this clause (2) will be a Change of Control if the Persons that beneficially own the Company’s
Voting Stock immediately prior to the transaction own, directly or indirectly, shares with a majority of the total voting power of all outstanding voting securities of the surviving or transferee Person that are entitled to vote generally in the
election of that Person’s board of directors, managers or trustees immediately after the transaction; or (3) the adoption of a plan relating to the Company’s liquidation or dissolution. Notwithstanding the foregoing, a transaction
will not be deemed to involve a Change of Control under clause (1) above if (i) the Company becomes a direct or indirect wholly-owned subsidiary of a holding company and (ii) (A) the direct or indirect holders of the Voting Stock of
such holding company immediately following that transaction are substantially the same as the holders of the Company’s Voting Stock immediately prior to that transaction or (B) immediately following that transaction no Person (other than a
holding company satisfying the requirements of this sentence) is the Beneficial Owner, directly or indirectly, of more than 50% of the Voting Stock of such holding company. 

“Change of Control Triggering Event” means the occurrence of both a Change of Control and a Rating Event. 

“Group” has the meaning given by Section 13(d) and 14(d) of the Exchange Act or any successor provisions and includes
any group acting for the purpose of acquiring, holding or disposing of securities within the meaning of Rule 13d-5(b)(1) under the Exchange Act or any successor provision. 

“Investment Grade Rating” means a rating equal to or higher than Baa3 (or the equivalent) by Moody’s and BBB- (or the
equivalent) by S&P, and the equivalent investment grade credit rating from any additional Rating Agency or Rating Agencies selected by the Company. 

“Moody’s” means Moody’s Investors Service, Inc., and its successors. 

“Person” has the meaning given by Section 13(d) and 14(d) of the Exchange Act or any successor provisions. 

  
 4 

 “Rating Agencies” means (1) each of Moody’s and S&P; and
(2) if either Moody’s or S&P ceases to rate the Notes or fails to make a rating of the Notes publicly available for reasons outside of the Company’s control, a “nationally recognized statistical rating organization”
within the meaning of Section 3(a)(62) of the Exchange Act selected by the Company (as certified by a resolution of the Board of Directors) as a replacement agency for Moody’s or S&P, or both of them, as the case may be. 

“Rating Event” means the rating on the applicable series of Notes is lowered by both of the Rating Agencies and the
applicable series of Notes is rated below an Investment Grade Rating by both of the Rating Agencies on any day during the period commencing 60 days prior to the first public notice of the occurrence of a Change of Control or the Company’s
intention to effect a Change of Control and ending 60 days following consummation of such Change of Control (which period will be extended so long as the rating of the applicable series of Notes is under publicly announced consideration for a
possible downgrade by any of the Rating Agencies). 
 “S&P” means Standard & Poor’s Rating Services, a
division of The McGraw-Hill Companies, Inc., and its successors. 
 “Voting Stock” as applied to stock of any Person, means
shares, interests, participations or other equivalents in the equity interest (however designated) in such Person having ordinary voting power for the election of a majority of the directors (or the equivalent) of such Person, other than shares,
interests, participations or other equivalents having such power only by reason of the occurrence of a contingency. 
 Section 4.6
Limitation on Liens. 
 (a) The Company shall not, nor shall it permit any of its Subsidiaries to, create or incur any Lien on any of
their respective Properties, whether now owned or hereafter acquired, or upon any income or profits therefrom, in order to secure any Indebtedness of the Company, without effectively providing that each series of the Notes shall be equally and
ratably secured until such time as such Indebtedness is no longer secured by such Lien, except: 
 (1) Liens existing as of the First Issue
Date; 
 (2) Liens granted after the First Issue Date on any of the Company or any of its Subsidiaries’ Properties securing
Indebtedness of the Company created in favor of the Holders of the Notes; 
 (3) Liens securing Indebtedness of the Company which are
incurred to extend, renew or refinance Indebtedness which is secured by Liens permitted to be incurred under the Indenture; provided that those Liens do not extend to or cover any of the Company or any of its Subsidiaries’ Property other
than the Property securing the Indebtedness being refinanced and that the principal amount of such Indebtedness does not exceed the principal amount of the Indebtedness being refinanced; 

(4) Liens created in substitution of or as replacements for any Liens permitted by the preceding clauses (1) through (3) directly above,
provided that, based on a good faith determination of an Officer of the Company, the Property encumbered under any such substitute or replacement Lien is substantially similar in nature to the Property encumbered by the otherwise permitted
Lien which is being replaced; and 

  
 5 

 (5) Permitted Liens. 

(b) Notwithstanding the foregoing, the Company and any of its Subsidiaries may, without securing any series of Notes, create or incur Liens
which would otherwise be subject to the restrictions set forth in the preceding paragraph, if after giving effect thereto, Exempted Debt does not exceed the greater of (x) 35% of Consolidated Net Worth calculated as of the date of the creation or
incurrence of the Lien or (y) 35% of Consolidated Net Worth calculated as of the First Issue Date. 
 Section 4.7 Limitation on Sale
and Lease-Back Transactions. 
 (a) The Company shall not and shall not permit any of its Subsidiaries to, enter into any sale and
lease-back transaction for the sale and leasing back of any Property, whether now owned or hereafter acquired, of the Company or any Subsidiary of the Company, unless: 

(1) such transaction was entered into prior to the First Issue Date; 

(2) such transaction was for the sale and leasing back of any Property by a Subsidiary of the Company to the Company; 

(3) such transaction involves a lease for less than three years; 

(4) the Company would be entitled to incur Indebtedness secured by a mortgage on the property to be leased in an amount equal to the
Attributable Liens with respect to such sale and lease-back transaction without equally and ratably securing the Notes pursuant to Section 4.6; or 

(5) the Company applies an amount equal to the fair value of the proceeds of the Property sold to the purchase of Property or to the
retirement of long-term Indebtedness of the Company or any of its Subsidiaries within 120 days of the effective date of any such sale and lease-back transaction. In lieu of applying such amount to such retirement, the Company may, or may cause any
of its Subsidiaries to, deliver debt securities to the Trustee therefor for cancellation, such debt securities to be credited at the cost thereof to the Company. 

(b) Notwithstanding the foregoing, the Company and any of its Subsidiaries may enter into any sale and lease-back transaction which would
otherwise be subject to the foregoing restrictions if after giving effect thereto and at the time of determination, Exempted Debt does not exceed the greater of (a) 35% of Consolidated Net Worth calculated as of the closing date of the sale and
lease-back transaction or (b) 35% of Consolidated Net Worth calculated as of the First Issue Date. 
 8. In addition to the definitions set
forth in Article I of the Indenture, each of the Notes shall include the following additional definitions, which, in the event of a conflict with the definition of terms in the Indenture, shall control: 

  
 6 

 “Attributable Liens” means in connection with a sale and lease-back
transaction the lesser of: 
 (1) the fair market value of the assets subject to such transaction; and 

(2) the present value (discounted at a rate per annum equal to the average interest borne by all outstanding debt securities issued under the
Indenture (which may include debt securities in addition to the Notes) determined on a weighted average basis and compounded semi-annually) of the obligations of the lessee for rental payments during the term of the related lease. 

“Business Day” means any day except a Saturday, Sunday or a legal holiday in the City of New York, New York (or in connection
with any payment, the place of payment) on which banking institutions are authorized or required by law, regulation or executive order to close. 

“Consolidated Net Worth” means, as of any date of determination, the Stockholders’ Equity of the Company and its
Consolidated Subsidiaries on that date. 
 “Consolidated Subsidiary” means, as of any date of determination and with
respect to any Person, any Subsidiary of that Person whose financial data is, in accordance with GAAP, reflected in that Person’s consolidated financial statements. 

“Credit Facilities” means, one or more debt facilities (including, without limitation, the Revolving Credit Agreement) or
commercial paper facilities, in each case, with banks or other institutional lenders providing for revolving credit loans, term loans, receivables financing (including through the sale of receivables to such lenders or to special purpose entities
formed to borrow from such lenders against such receivables) or letters of credit, in each case, as amended, restated, modified, renewed, refunded, replaced (whether upon or after termination or otherwise) or refinanced (including by means of sales
of debt securities to institutional investors) in whole or in part from time to time. 
 “Exempted Debt” means the sum of
the following as of the date of determination: 
 (1) Indebtedness of the Company incurred after the First Issue Date and secured by Liens
not permitted by Section 4.6(a) above; and 
 (2) Attributable Liens of the Company and any of its Subsidiaries in respect of sale and
lease-back transactions entered into after the First Issue Date pursuant to Section 4.7(b) above. 
 “Finance Lease”
means, as to any Person, a lease of any Property by that Person as lessee that is, or should be recorded as a “finance lease” on the balance sheet of that Person prepared in accordance with GAAP. 

“First Issue Date” means February 22, 2022. 

“GAAP” means accounting principles generally accepted in the United States set forth in the Accounting Standards Codification
of the Financial Accounting Standards Board or in such other documents by such other entity as have been approved by a significant segment of the accounting profession, which are in effect as of the date of determination. 

  
 7 

 “Governmental Agency” means: 

(1) any foreign, federal, state, county or municipal government, or political subdivision thereof; 

(2) any governmental or quasi-governmental agency, authority, board, bureau, commission, department, instrumentality or public body; 

(3) any court or administrative tribunal; and 

(4) with respect to any Person, any arbitration tribunal or other nongovernmental authority to whose jurisdiction that Person has consented.

 “Hedging Obligations” means, with respect to any specified Person, the obligations of such Person under: 

(1) interest rate swap agreements (whether from fixed to floating or from floating to fixed), interest rate cap agreements and interest rate
collar agreements; 
 (2) other agreements or arrangements designed to manage interest rates or interest rate risk; and 

(3) other agreements or arrangements designed to protect such Person against fluctuations in currency exchange rates or commodity prices. 

“Indebtedness” of any Person means, without duplication, any indebtedness, whether or not contingent, in respect of borrowed
money or evidenced by bonds, notes, debentures or similar instruments or letters of credit (or reimbursement agreements with respect thereto) or representing the balance deferred and unpaid of the purchase price of any Property (including pursuant
to Finance Leases), except any such balance that constitutes an accrued expense or trade payable, if and to the extent any of the foregoing indebtedness would appear as a liability upon a balance sheet of such Person prepared on a consolidated basis
in accordance with GAAP (but does not include contingent liabilities which appear only in a footnote to a balance sheet), and shall also include, to the extent not otherwise included, the guaranty of items which would be included within this
definition. 
 “Laws” means, collectively, all foreign, federal, state and local statutes, treaties, rules, regulations,
ordinances, codes and administrative or controlling precedents of any Governmental Agency. 
 “Lien” means any lien,
security interest, charge or encumbrance of any kind (including any conditional sale or other title retention agreement, any lease in the nature thereof, and any agreement to give any security interest). 

“Make-Whole Amount” means the excess of (1) the net present value, on the redemption date, of the principal being
redeemed or paid and the amount of interest (exclusive of interest accrued to the date of redemption) that would have been payable if such redemption had not been made (calculated as if the maturity date of such series of Notes was the par call date
relating to such series of Notes, to the extent applicable), over (2) the aggregate principal amount of such 

  
 8 

 series of Notes being redeemed or paid. Net present value shall be determined by discounting, on a
semi-annual basis, such principal and interest at the Reinvestment Rate (as defined below and as determined on the third Business Day preceding the date of redemption) from the respective dates on which such principal and interest would have been
payable if such redemption had not been made. 
 “Permitted Liens” means: 

(1) Liens securing Indebtedness under Credit Facilities; 

(2) Liens on accounts receivable, merchandise inventory, equipment, and patents, trademarks, trade names and other intangibles, securing
Indebtedness of the Company; 
 (3) Liens on any assets of the Company, any of its Subsidiaries’ assets, or the assets of any joint
venture to which the Company or any of its Subsidiaries is a party, created solely to secure obligations incurred to finance the refurbishment, improvement or construction of such asset, which obligations are incurred no later than 24 months after
completion of such refurbishment, improvement or construction, and all renewals, extensions, refinancings, replacements or refundings of such obligations; 

(4) (a) Liens given to secure the payment of the purchase price incurred in connection with the acquisition (including acquisition through
merger or consolidation) of Property (including shares of stock), including Finance Lease transactions in connection with any such acquisition, and (b) Liens existing on Property at the time of acquisition thereof or at the time of acquisition
by the Company or one of its Subsidiaries of any Person then owning such Property whether or not such existing Liens were given to secure the payment of the purchase price of the Property to which they attach; provided that, with respect to
clause (a), the Liens shall be given within 24 months after such acquisition and shall attach solely to the Property acquired or purchased and any improvements then or thereafter placed thereon; 

(5) Liens in favor of customs and revenue authorities arising as a matter of law to secure payment of customs duties in connection with the
importation of goods; 
 (6) Liens upon specific items of inventory or other goods and proceeds of any Person securing such Person’s
obligations in respect of bankers’ acceptances issued or created for the account of such Person to facilitate the purchase, shipment or storage of such inventory or other goods; 

(7) Liens securing reimbursement obligations with respect to letters of credit that encumber documents and other Property relating to such
letters of credit and the products and proceeds thereof; 
 (8) Liens on key-man life insurance policies granted to secure Indebtedness of
the 
 Company against the cash surrender value thereof; 

(9) Liens encumbering customary initial deposits and margin deposits and other Liens in the ordinary course of business, in each case securing
Hedging Obligations and forward contract, option, futures contracts, futures options or similar agreements or arrangements designed to protect the Company or any of its Subsidiaries from fluctuations in interest rates, currencies or the price of
commodities; 

  
 9 

 (10) Liens arising out of conditional sale, title retention, consignment or similar
arrangements for the sale of goods entered into by Company or any of its Subsidiaries in the ordinary course of business; 
 (11)
pre-existing Liens on assets acquired by the Company or any of its Subsidiaries after the First Issue Date; 
 (12) Liens in favor of the
Company or in favor of any of its Subsidiaries; 
 (13) inchoate Liens incident to construction or maintenance of real property, or Liens
incident to construction or maintenance of real property, now or hereafter filed of record for sums not yet delinquent or being contested in good faith, if reserves or other appropriate provisions, if any, as shall be required by GAAP shall have
been made therefore; 
 (14) statutory Liens arising in the ordinary course of business with respect to obligations which are not delinquent
or are being contested in good faith, if reserves or other appropriate provisions, if any, as shall be required by GAAP shall have been made therefore; 

(15) Liens consisting of pledges or deposits to secure obligations under workers’ compensation laws or similar legislation, including
Liens of judgments thereunder which are not currently dischargeable; 
 (16) Liens consisting of pledges or deposits of Property to secure
performance in connection with operating leases made in the ordinary course of business to which Company or any of its Subsidiaries is a party as lessee, provided the aggregate value of all such pledges and deposits in connection with any
such lease does not at any time exceed 162⁄3% of the annual fixed rentals payable under such lease; 

(17) Liens consisting of deposits of Property to secure statutory obligations of the 

Company or statutory obligations of any of its Subsidiaries in the ordinary course of its business; 

(18) Liens consisting of deposits of Property to secure (or in lieu of) surety, appeal or customs bonds in proceedings to which the Company or
any of its Subsidiaries is a party in the ordinary course of its business, but not in excess of $75,000,000; 
 (19) purchase money Liens or
purchase money security interests upon or in any Property acquired or held by Company or any of its Subsidiaries in the ordinary course of business to secure the purchase price of such Property or to secure Indebtedness incurred solely for the
purpose of financing the acquisition of such Property; 
 (20) Liens on an asset created in connection with the acquisition, construction or
development of additions, extensions or improvements to such asset which shall be financed by obligations described in Sections 142, 144(a) or 144(c) of the Internal Revenue Code of 1986, as amended, or by obligations entitled to substantially
similar tax benefits under other legislation or regulations in effect from time to time; and 

  
 10 

 (21) Liens on Property subject to escrow or similar arrangements established in connection
with litigation settlements. 
 “Person” means any individual, corporation, partnership, joint venture, association,
limited liability company, joint-stock company, trust, unincorporated organization or government or any agency or political subdivision thereof. 

“Property” means any property or asset, whether real, personal or mixed, or tangible or 

intangible. 

“Reinvestment Rate” means, for the 2029 Notes, 0.200%, for the 2032 Notes, 0.250%, for the 2052 Notes, 0.300% and for the
2062 Notes, 0.350%, in each case plus the weekly yield for the most recent week set forth in the most recent Statistical Release (as defined below) for the constant maturity U.S. Treasury security (rounded to the nearest month) corresponding to the
remaining life to maturity, as of the payment date of the principal being redeemed or paid. If no maturity exactly corresponds to such maturity, yields for the two published maturities most closely corresponding to such maturity shall be calculated
pursuant to the immediately preceding sentence and the Reinvestment Rate shall be interpolated or extrapolated from such yields on a straight-line basis, rounding in each of such relevant periods to the nearest month. For the purpose of calculating
the Reinvestment Rate, the most recent Statistical Release published prior to the date of determination of the Make-Whole Amount shall be used. 

“Revolving Credit Agreement” means the Second Amended and Restated Credit Agreement, dated as of December 12, 2019, among the
Company, the banks therein named, Citibank, N.A., as administrative agent, JPMorgan Chase Bank, N.A., as syndication agent, and Citibank, N.A., JPMorgan Chase Bank, N.A., Barclays Bank PLC, BofA Securities, Inc., Goldman Sachs Bank USA and Morgan
Stanley Senior Funding, Inc., as joint lead arrangers and joint book runners, as such agreement may be further amended (including any amendment, restatement, refinancing and successors thereof), supplemented or otherwise modified from time to time,
including any increase in the principal amount of the obligations thereunder. 
 “Statistical Release” means the
statistical release designated “H.15” or any comparable online data source or publication which is made available by the Federal Reserve System and which establishes yields on actively traded U.S. government securities adjusted to constant
maturities, or, if such Statistical Release is not published at the time of any determination under the Indenture, then such other reasonably comparable index which shall be designated by the Company. 

“Stockholders’ Equity” means, as of any date of determination, stockholders’ equity as of that date determined in
accordance with GAAP; provided that there shall be excluded from Stockholders’ Equity any amount attributable to capital stock that is, directly or indirectly, required to be redeemed or repurchased by the issuer thereof at a specified
date or upon the occurrence of specified events or at the election of the holder thereof. 
 “Subsidiary” of any specified
person means any corporation, association or other business entity of which more than 50% of the total voting power of shares of capital stock entitled (without regard to the occurrence of any contingency) to vote in the election of directors,
managers or trustees thereof is at the time owned or controlled, directly or indirectly, by such person or one or more of the other Subsidiaries of that person or a combination thereof. 

  
 11 

 9. Section 9.1(h) of the Indenture shall be amended and restated solely with respect to the
Notes as follows: 
 (h) to make any change that does not adversely affect the rights of any Securityholder in any material respect; 

10. Pursuant to Section 3.4 of the Indenture, solely with respect to the Notes, notices of redemption sent by the Company pursuant to the
Indenture may be conditional. 
 11. The Depository for the Notes shall be The Depository Trust Company (“DTC”). 

12. The undersigned is authorized to approve the form, terms and conditions of the Notes. 

13. The undersigned has read the provisions of the Indenture, including the covenants and conditions precedent, pertaining to the issuance of
the Notes. 
 14. In connection with this Certificate, the undersigned has examined the documents, corporate records and certificates and has
made such inquiries of the other officers of the Company, which he or she has deemed necessary to enable him or her to express an informed opinion as to whether or not such comments and conditions have been complied with. 

15. In the opinion of the undersigned, all of the conditions and covenants related to the issuance of the Notes have been complied with. 

[Signature follows] 

  
 12 

 IN WITNESS WHEREOF, the undersigned has executed this Officer’s Certificate as
of the date first set forth above. 
  

					
	By:	 	 /s/ Justin G. Claeys

		 	Name:	 	Justin G. Claeys
		 	Title:	 	Vice President, Finance and Treasurer

 Signature Page to Officer’s Certificate for the Notes 

 Annex A 

Form of 2029 Note 

 [Face of Note] 

 
 CUSIP 031162DD9 

3.000% Senior Notes due 2029 
  

			
	No. ___	  	$__________

 AMGEN INC. 

promises to pay to CEDE & CO. or registered assigns, 

the principal sum of ____________ DOLLARS on February 22, 2029. 

Interest Payment Dates: February 22 and August 22 

Record Dates: 15th day prior to February 22 and August 22 

Dated: February 22, 2022 

 
			
	AMGEN INC.
		
	By:	 	  

		 	Name:
		 	Title:

  

			
	This is one of the Notes referred to in the within-mentioned Indenture:
	
	THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., as Trustee
		
	By:	 	  

		 	Authorized Officer
	
	Authentication Date:
                                         
   

 [REVERSE SIDE OF NOTE] 

3.000% SENIOR NOTES DUE 2029 

THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF THE DEPOSITORY
OR A NOMINEE OF THE DEPOSITORY. THIS SECURITY IS EXCHANGEABLE FOR SECURITIES REGISTERED IN THE NAME OF A PERSON OTHER THAN THE DEPOSITORY OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE, AND MAY NOT BE TRANSFERRED EXCEPT
AS A WHOLE BY THE DEPOSITORY TO A NOMINEE OF THE DEPOSITORY, BY A NOMINEE OF THE DEPOSITORY TO THE DEPOSITORY OR ANOTHER NOMINEE OF THE DEPOSITORY OR BY THE DEPOSITORY OR ANY SUCH NOMINEE TO A SUCCESSOR DEPOSITORY OR A NOMINEE OF SUCH A SUCCESSOR
DEPOSITORY. 
 UNLESS THIS CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY TO THE ISSUER OR ITS
AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (AND ANY
PAYMENT HEREON IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL
SINCE THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 
 Capitalized terms used herein have the meanings assigned
to them in the Indenture referred to below unless otherwise indicated. 
  

	 	(1)	 INTEREST. Amgen Inc., a Delaware corporation (the “Company”), promises to pay interest on the
principal amount of this Note at 3.000% per annum from February 22, 2022 until maturity. The Company will pay interest in cash semi-annually in arrears on February 22 and August 22 of each year, or if any such day is not a Business
Day, on the next succeeding Business Day (each, an “Interest Payment Date”). Interest on the Notes will accrue from the most recent date to which interest has been paid or, if no interest has been paid, from the date of issuance;
provided that the first Interest Payment Date shall be August 22, 2022; provided further that after August 22, 2022, if there is no existing Default in the payment of interest, and if this Note is authenticated between a record date
referred to on the face hereof and the next succeeding Interest Payment Date, interest shall accrue from such next succeeding Interest Payment Date. The interest rate will be computed on the basis of a 360-day
year of twelve 30-day calendar months. 

  

	 	(2)	 METHOD OF PAYMENT. The Company will pay interest on the Notes (except defaulted interest) to the Persons who
are registered Holders of Notes at the close of business on the day that is 15 days prior to the next succeeding Interest Payment Date (whether or not such day is a Business Day), even if such Notes are canceled

	 	
after such record date and on or before such Interest Payment Date, except as provided in Section 2.13 of the Indenture with respect to defaulted interest. The Notes will be payable as to
principal and interest at the office or agency of the Company maintained for such purpose in the Borough of Manhattan, the City and State of New York (or, if the Company fails to maintain such office or agency, at the corporate trust office of the
trustee in New York, New York or if the trustee does not maintain an office in New York, at the office of a paying agent in New York), or, at the option of the Company, payment of interest may be made by check mailed to the Holders at their
addresses set forth in the register of Holders; provided that payment by wire transfer of immediately available funds will be required with respect to principal of and interest on all Global Securities and all other Notes the Holders of which
will have provided wire transfer instructions to the Company or the Paying Agent. Such payment will be in the currency of the United States of America. 

  

	 	(3)	 PAYING AGENT AND REGISTRAR. Initially, The Bank of New York Mellon Trust Company, N.A., the Trustee under the
Indenture, will act as Paying Agent and Registrar. The Company may change any Paying Agent or Registrar without notice to any Holder. The Company or any of its Subsidiaries may act in any such capacity. 

 

	 	(4)	 INDENTURE. The terms of the Notes include those stated in the Indenture dated May 22, 2014, between the
Company and the Trustee (the “Indenture”), and those made part of the Indenture by the Officer’s Certificate dated February 22, 2022, delivered pursuant thereto (the “Officer’s Certificate”) and the
TIA. The Notes are subject to all such terms, and the Holders are referred to the Indenture and the TIA for a statement of them. 

  

	 	(5)	 OPTIONAL REDEMPTION. At any time prior to maturity, the Company will have the option to redeem all or a part of
the Notes upon not less than 10 nor more than 60 days’ notice. If the Notes are redeemed before December 22, 2028 (two months prior to the maturity date of the Notes), the redemption price will equal the sum of (1) 100% of the principal
amount of any Notes being redeemed, plus accrued and unpaid interest to, but not including, the redemption date, and (2) the Make-Whole Amount. If the Notes are redeemed on or after December 22, 2028 (two months prior to the maturity date
of the Notes), the redemption price will equal 100% of the principal amount being redeemed, plus accrued and unpaid interest to, but not including, the redemption date. Unless the Company defaults in the payment of the redemption price, interest
will cease to accrue on the Notes or portions thereof called for redemption on the applicable redemption date. 

  

	 	(6)	 NOTICE OF REDEMPTION. Notice of redemption will be mailed at least 10 days but not more than 60 days before the
redemption date to each Holder whose Notes are to be redeemed at its registered address, except that redemption notices may be mailed more than 60 days prior to a redemption date if the notice is issued in connection with a defeasance of the Notes
or a satisfaction or discharge of the Indenture. Notes in denominations larger than $2,000 may be redeemed in part but only in whole multiples of $1,000, unless all of the Notes held by a Holder are to be redeemed. Notices of redemption for the
Notes may be conditional. 

	 	(7)	 MANDATORY REDEMPTION. Except as provided in Section 8 below, the Company is not required to make mandatory
redemption or sinking fund payments with respect to the Notes. 

  

	 	(8)	 CHANGE OF CONTROL TRIGGERING EVENT. In the event of a Change of Control Triggering Event, the Holders may
require the Company to purchase for cash all or a portion of their Notes at a purchase price equal to 101% of the principal amount of the notes, plus accrued and unpaid interest, if any, pursuant to the provisions of Section 7 of the
Officer’s Certificate. If holders of not less than 90% in aggregate principal amount of the outstanding Notes validly tender and do not withdraw such Notes in a Change Of Control Offer and the Company, or any third party making such an offer in
lieu of the Company, purchases all of the Notes validly tendered and not withdrawn by such holders, the Company or such third party will have the right, upon not less than 10 days nor more than 60 days’ prior notice, provided that such notice
is given not more than 30 days following such repurchase pursuant to the Change Of Control Offer described above, to redeem all Notes that remain outstanding following such purchase on a date specified in such notice (the “Second Change Of
Control Payment Date”) and at a price in cash equal to 101% of the aggregate principal amount of Notes repurchased plus any accrued and unpaid interest on the Notes repurchased to, but not including, the Second Change Of Control Payment
Date. 

  

	 	(9)	 DEFEASANCE PRIOR TO MATURITY. The Indenture contains provisions for defeasance of (i) the entire
indebtedness of the Notes or (ii) certain covenants and Events of Default with respect to the Notes, in each case upon compliance with certain conditions set forth therein. 

 

	 	(10)	 RESTRICTIVE COVENANTS. The Indenture and the Officer’s Certificate impose certain limitations on the
Company and its Subsidiaries, including limitations on the Company’s and its Subsidiaries’ ability to create or incur certain Liens on any of their respective properties or assets and to enter into certain sale and lease-back transactions
and on the Company’s ability to engage in mergers or consolidations or the conveyance, transfer or lease of all or substantially all of its properties and assets. These limitations are subject to a number of important qualifications and
exceptions and reference is made to the Indenture and the Officer’s Certificate for a description thereof. 

  

	 	(11)	 DENOMINATIONS, TRANSFER, EXCHANGE. The Notes are in registered form without coupons in denominations of $2,000
and integral multiples of $1,000. The transfer of Notes may be registered and Notes may be exchanged as provided in the Indenture. The Registrar and the Trustee may require a Holder, among other things, to furnish appropriate endorsements and
transfer documents and the Company may require a Holder to pay any taxes and fees required by law or permitted by the Indenture. The Company need not exchange or register the 

	 	
transfer of any Note or portion of a Note selected for redemption, except for the unredeemed portion of any Note being redeemed in part. Also, the Company need not exchange or register the
transfer of any Notes for a period of 15 days before a selection of Notes to be redeemed or during the period between a record date and the corresponding Interest Payment Date. 

 

	 	(12)	 PERSONS DEEMED OWNERS. The registered Holder of a Note may be treated as its owner for all purposes.

  

	 	(13)	 AMENDMENT, SUPPLEMENT AND WAIVER. Subject to certain exceptions, the Indenture or the Notes may be amended or
supplemented with the consent of the Holders of at least a majority in aggregate principal amount of the then outstanding Notes voting as a single class, and any existing Default or Event or Default or compliance with any provision of the Indenture
or the Notes may be waived with the consent of the Holders of a majority in aggregate principal amount of the then outstanding Notes voting as a single class. Without the consent of any Holder of a Note, the Indenture or the Notes may be amended or
supplemented to cure any ambiguity, defect or inconsistency; to comply with Article V of the Indenture; to provide for uncertificated Notes in addition to or in place of certificated Notes; to add guarantees with respect to the Notes or secure the
Notes; to surrender any of the Company’s rights or powers under the Indenture; to add covenants or events of default for the benefit of the Holders of the Notes; to comply with the applicable procedures of the applicable depositary; to make any
change that would not adversely affect the rights under the Indenture of any such Holder in any material respect; to provide for the issuance of and establish the form and terms and conditions of Notes of any series as permitted by the Indenture; to
evidence and provide for the acceptance of appointment under the Indenture by a successor trustee with respect to the Notes and to add to or change any of the provisions of the Indenture necessary to provide for the administration of the trusts in
the Indenture by more than one trustee; or to comply with the requirements of the SEC in order to effect or maintain the qualification of the Indenture under the TIA. No amendment to cure any ambiguity, defect or inconsistency in the Indenture made
solely to conform the Indenture to the description of notes contained in the Prospectus Supplement related to the Notes, dated February 17, 2022, will be deemed to adversely affect the interests of the Holders of the Notes.

  

	 	(14)	 DEFAULTS AND REMEDIES. If an Event of Default shall occur and be continuing, the principal of the Notes may be
declared (or, in certain cases, shall ipso facto become) due and payable in the manner and with the effect provided in the Indenture. 

  

	 	(15)	 TRUSTEE DEALINGS WITH COMPANY. The Trustee under the Indenture, in its individual or any other capacity, may
deal with the Company or an Affiliate of the Company with the same rights it would have if it were not Trustee. 

	 	(16)	 NO RECOURSE AGAINST OTHERS. A director, officer, employee or stockholder of the Company shall not have any
liability for any obligations of the Company under the Notes or the Indenture or for any claim based on, in respect of, or by reason of, such obligations or their creation. Each Holder by accepting a Note waives and releases all such liability. The
waiver and release are part of the consideration for the issuance of the Notes. 

  

	 	(17)	 AUTHENTICATION. This Note will not be valid until authenticated by the manual signature of the Trustee or an
authenticating agent. 

  

	 	(18)	 ABBREVIATIONS. Customary abbreviations may be used in the name of a Holder or an assignee, such as: TEN COM (=
tenants in common), TEN ENT (= tenants by the entireties), JT TEN (= joint tenants with right of survivorship and not as tenants in common), CUST (= Custodian), and U/G/M/A (= Uniform Gifts to Minors Act). 

 

	 	(19)	 CUSIP NUMBERS. Pursuant to a recommendation promulgated by the Committee on Uniform Security Identification
Procedures, the Company has caused CUSIP numbers to be printed on the Notes, and the Trustee may use CUSIP numbers in notices of redemption as a convenience to Holders. No representation is made as to the accuracy of such numbers either as printed
on the Notes or as contained in any notice of redemption, and reliance may be placed only on the other identification numbers placed thereon. 

  

	 	(20)	 GOVERNING LAW. THE INDENTURE AND THIS NOTE, INCLUDING ANY CLAIM OR CONTROVERSY ARISING OUT OF OR RELATED TO THE
INDENTURE OR THIS NOTE, SHALL BE GOVERNED BY THE LAWS OF THE STATE OF NEW YORK. 

 The Company will furnish to any Holder
upon written request and without charge a copy of the Indenture and/or the Officer’s Certificate. 
 Requests may be made
to: 
 Amgen Inc. 
 One
Amgen Center Drive 
 Thousand Oaks, CA 91320-1799 

Attention: Investor Relations 

 ASSIGNMENT FORM 

To assign this Note, fill in the form below: 

(I) or (we) assign and transfer this Note to:
                                         
                        

                       
                     (Insert assignee’s legal name) 
  

 
 (Insert assignee’s soc. sec. or
tax I.D. no.) 
  
  

 
  
  

 
  

 
 (Print or type assignee’s name,
address and zip code) 
 and irrevocably appoint
                                         
                                         
                                         
                                         
                                         to
transfer this Note on the books of the Company. The agent may substitute another to act for him. 
 Date:
                                     

 

			
	Your Signature:	 	  

		 	(Sign exactly as your name appears on the face of this Note)

 Signature Guarantee*:
                                 

 

	*	 Participant in a recognized Signature Guarantee Medallion Program (or other signature guarantor acceptable to
the Trustee). 

  
  

 Annex B 

Form of 2032 Note 

 [Face of Note] 
  

 
 CUSIP 031162DE7 

3.350% Senior Notes due 2032 
  

			
	No. ___	  	$___________

 AMGEN INC. 

promises to pay to CEDE & CO. or registered assigns, 

the principal sum of __________ DOLLARS on February 22, 2032. 

Interest Payment Dates: February 22 and August 22 

Record Dates: 15th day prior to February 22 and August 22 

Dated: February 22, 2022 

 
			
	AMGEN INC.
		
	By:	 	  

		 	Name:
		 	Title:

  

			
	This is one of the Notes referred to in the within-mentioned Indenture:
	
	THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., as Trustee
		
	By:	 	  

		 	Authorized Officer
	
	Authentication Date:
                                         
   

 [REVERSE SIDE OF NOTE] 

3.350% SENIOR NOTES DUE 2032 

THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF THE DEPOSITORY
OR A NOMINEE OF THE DEPOSITORY. THIS SECURITY IS EXCHANGEABLE FOR SECURITIES REGISTERED IN THE NAME OF A PERSON OTHER THAN THE DEPOSITORY OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE, AND MAY NOT BE TRANSFERRED EXCEPT
AS A WHOLE BY THE DEPOSITORY TO A NOMINEE OF THE DEPOSITORY, BY A NOMINEE OF THE DEPOSITORY TO THE DEPOSITORY OR ANOTHER NOMINEE OF THE DEPOSITORY OR BY THE DEPOSITORY OR ANY SUCH NOMINEE TO A SUCCESSOR DEPOSITORY OR A NOMINEE OF SUCH A SUCCESSOR
DEPOSITORY. 
 UNLESS THIS CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY TO THE ISSUER OR ITS
AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (AND ANY
PAYMENT HEREON IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL
SINCE THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 
 Capitalized terms used herein have the meanings assigned
to them in the Indenture referred to below unless otherwise indicated. 
  

	 	(1)	 INTEREST. Amgen Inc., a Delaware corporation (the “Company”), promises to pay interest on the
principal amount of this Note at 3.350% per annum from February 22, 2022 until maturity. The Company will pay interest in cash semi-annually in arrears on February 22 and August 22 of each year, or if any such day is not a Business
Day, on the next succeeding Business Day (each, an “Interest Payment Date”). Interest on the Notes will accrue from the most recent date to which interest has been paid or, if no interest has been paid, from the date of issuance;
provided that the first Interest Payment Date shall be August 22, 2022; provided further that after August 22, 2022, if there is no existing Default in the payment of interest, and if this Note is authenticated between a record date
referred to on the face hereof and the next succeeding Interest Payment Date, interest shall accrue from such next succeeding Interest Payment Date. The interest rate will be computed on the basis of a 360-day
year of twelve 30-day calendar months. 

  

	 	(2)	 METHOD OF PAYMENT. The Company will pay interest on the Notes (except defaulted interest) to the Persons who
are registered Holders of Notes at the close of business on the day that is 15 days prior to the next succeeding Interest Payment Date (whether or not such day is a Business Day), even if such Notes are canceled

	 	
after such record date and on or before such Interest Payment Date, except as provided in Section 2.13 of the Indenture with respect to defaulted interest. The Notes will be payable as to
principal and interest at the office or agency of the Company maintained for such purpose in the Borough of Manhattan, the City and State of New York (or, if the Company fails to maintain such office or agency, at the corporate trust office of the
trustee in New York, New York or if the trustee does not maintain an office in New York, at the office of a paying agent in New York), or, at the option of the Company, payment of interest may be made by check mailed to the Holders at their
addresses set forth in the register of Holders; provided that payment by wire transfer of immediately available funds will be required with respect to principal of and interest on all Global Securities and all other Notes the Holders of which
will have provided wire transfer instructions to the Company or the Paying Agent. Such payment will be in the currency of the United States of America. 

  

	 	(3)	 PAYING AGENT AND REGISTRAR. Initially, The Bank of New York Mellon Trust Company, N.A., the Trustee under the
Indenture, will act as Paying Agent and Registrar. The Company may change any Paying Agent or Registrar without notice to any Holder. The Company or any of its Subsidiaries may act in any such capacity. 

 

	 	(4)	 INDENTURE. The terms of the Notes include those stated in the Indenture dated May 22, 2014, between the
Company and the Trustee (the “Indenture”), and those made part of the Indenture by the Officer’s Certificate dated February 22, 2022, delivered pursuant thereto (the “Officer’s Certificate”) and the
TIA. The Notes are subject to all such terms, and the Holders are referred to the Indenture and the TIA for a statement of them. 

  

	 	(5)	 OPTIONAL REDEMPTION. At any time prior to maturity, the Company will have the option to redeem all or a part of
the Notes upon not less than 10 nor more than 60 days’ notice. If the Notes are redeemed before November 22, 2031 (three months prior to the maturity date of the Notes), the redemption price will equal the sum of (1) 100% of the principal
amount of any Notes being redeemed, plus accrued and unpaid interest to, but not including, the redemption date, and (2) the Make-Whole Amount. If the Notes are redeemed on or after November 22, 2031 (three months prior to the maturity
date of the Notes), the redemption price will equal 100% of the principal amount being redeemed, plus accrued and unpaid interest to, but not including, the redemption date. Unless the Company defaults in the payment of the redemption price,
interest will cease to accrue on the Notes or portions thereof called for redemption on the applicable redemption date. 

  

	 	(6)	 NOTICE OF REDEMPTION. Notice of redemption will be mailed at least 10 days but not more than 60 days before the
redemption date to each Holder whose Notes are to be redeemed at its registered address, except that redemption notices may be mailed more than 60 days prior to a redemption date if the notice is issued in connection with a defeasance of the Notes
or a satisfaction or discharge of the Indenture. Notes in denominations larger than $2,000 may be redeemed in part but only in whole multiples of $1,000, unless all of the Notes held by a Holder are to be redeemed. Notices of redemption for the
Notes may be conditional. 

	 	(7)	 MANDATORY REDEMPTION. Except as provided in Section 8 below, the Company is not required to make mandatory
redemption or sinking fund payments with respect to the Notes. 

  

	 	(8)	 CHANGE OF CONTROL TRIGGERING EVENT. In the event of a Change of Control Triggering Event, the Holders may
require the Company to purchase for cash all or a portion of their Notes at a purchase price equal to 101% of the principal amount of the notes, plus accrued and unpaid interest, if any, pursuant to the provisions of Section 7 of the
Officer’s Certificate. If holders of not less than 90% in aggregate principal amount of the outstanding Notes validly tender and do not withdraw such Notes in a Change Of Control Offer and the Company, or any third party making such an offer in
lieu of the Company, purchases all of the Notes validly tendered and not withdrawn by such holders, the Company or such third party will have the right, upon not less than 10 days nor more than 60 days’ prior notice, provided that such notice
is given not more than 30 days following such repurchase pursuant to the Change Of Control Offer described above, to redeem all Notes that remain outstanding following such purchase on a date specified in such notice (the “Second Change Of
Control Payment Date”) and at a price in cash equal to 101% of the aggregate principal amount of Notes repurchased plus any accrued and unpaid interest on the Notes repurchased to, but not including, the Second Change Of Control Payment
Date. 

  

	 	(9)	 DEFEASANCE PRIOR TO MATURITY. The Indenture contains provisions for defeasance of (i) the entire
indebtedness of the Notes or (ii) certain covenants and Events of Default with respect to the Notes, in each case upon compliance with certain conditions set forth therein. 

 

	 	(10)	 RESTRICTIVE COVENANTS. The Indenture and the Officer’s Certificate impose certain limitations on the
Company and its Subsidiaries, including limitations on the Company’s and its Subsidiaries’ ability to create or incur certain Liens on any of their respective properties or assets and to enter into certain sale and lease-back transactions
and on the Company’s ability to engage in mergers or consolidations or the conveyance, transfer or lease of all or substantially all of its properties and assets. These limitations are subject to a number of important qualifications and
exceptions and reference is made to the Indenture and the Officer’s Certificate for a description thereof. 

  

	 	(11)	 DENOMINATIONS, TRANSFER, EXCHANGE. The Notes are in registered form without coupons in denominations of $2,000
and integral multiples of $1,000. The transfer of Notes may be registered and Notes may be exchanged as provided in the Indenture. The Registrar and the Trustee may require a Holder, among other things, to furnish appropriate endorsements and
transfer documents and the Company may require a Holder to pay any taxes and fees required by law or permitted by the Indenture. The Company need not exchange or register the 

	 	
transfer of any Note or portion of a Note selected for redemption, except for the unredeemed portion of any Note being redeemed in part. Also, the Company need not exchange or register the
transfer of any Notes for a period of 15 days before a selection of Notes to be redeemed or during the period between a record date and the corresponding Interest Payment Date. 

 

	 	(12)	 PERSONS DEEMED OWNERS. The registered Holder of a Note may be treated as its owner for all purposes.

  

	 	(13)	 AMENDMENT, SUPPLEMENT AND WAIVER. Subject to certain exceptions, the Indenture or the Notes may be amended or
supplemented with the consent of the Holders of at least a majority in aggregate principal amount of the then outstanding Notes voting as a single class, and any existing Default or Event or Default or compliance with any provision of the Indenture
or the Notes may be waived with the consent of the Holders of a majority in aggregate principal amount of the then outstanding Notes voting as a single class. Without the consent of any Holder of a Note, the Indenture or the Notes may be amended or
supplemented to cure any ambiguity, defect or inconsistency; to comply with Article V of the Indenture; to provide for uncertificated Notes in addition to or in place of certificated Notes; to add guarantees with respect to the Notes or secure the
Notes; to surrender any of the Company’s rights or powers under the Indenture; to add covenants or events of default for the benefit of the Holders of the Notes; to comply with the applicable procedures of the applicable depositary; to make any
change that would not adversely affect the rights under the Indenture of any such Holder in any material respect; to provide for the issuance of and establish the form and terms and conditions of Notes of any series as permitted by the Indenture; to
evidence and provide for the acceptance of appointment under the Indenture by a successor trustee with respect to the Notes and to add to or change any of the provisions of the Indenture necessary to provide for the administration of the trusts in
the Indenture by more than one trustee; or to comply with the requirements of the SEC in order to effect or maintain the qualification of the Indenture under the TIA. No amendment to cure any ambiguity, defect or inconsistency in the Indenture made
solely to conform the Indenture to the description of notes contained in the Prospectus Supplement related to the Notes, dated February 17, 2022, will be deemed to adversely affect the interests of the Holders of the Notes.

  

	 	(14)	 DEFAULTS AND REMEDIES. If an Event of Default shall occur and be continuing, the principal of the Notes may be
declared (or, in certain cases, shall ipso facto become) due and payable in the manner and with the effect provided in the Indenture. 

  

	 	(15)	 TRUSTEE DEALINGS WITH COMPANY. The Trustee under the Indenture, in its individual or any other capacity, may
deal with the Company or an Affiliate of the Company with the same rights it would have if it were not Trustee. 

	 	(16)	 NO RECOURSE AGAINST OTHERS. A director, officer, employee or stockholder of the Company shall not have any
liability for any obligations of the Company under the Notes or the Indenture or for any claim based on, in respect of, or by reason of, such obligations or their creation. Each Holder by accepting a Note waives and releases all such liability. The
waiver and release are part of the consideration for the issuance of the Notes. 

  

	 	(17)	 AUTHENTICATION. This Note will not be valid until authenticated by the manual signature of the Trustee or an
authenticating agent. 

  

	 	(18)	 ABBREVIATIONS. Customary abbreviations may be used in the name of a Holder or an assignee, such as: TEN COM (=
tenants in common), TEN ENT (= tenants by the entireties), JT TEN (= joint tenants with right of survivorship and not as tenants in common), CUST (= Custodian), and U/G/M/A (= Uniform Gifts to Minors Act). 

 

	 	(19)	 CUSIP NUMBERS. Pursuant to a recommendation promulgated by the Committee on Uniform Security Identification
Procedures, the Company has caused CUSIP numbers to be printed on the Notes, and the Trustee may use CUSIP numbers in notices of redemption as a convenience to Holders. No representation is made as to the accuracy of such numbers either as printed
on the Notes or as contained in any notice of redemption, and reliance may be placed only on the other identification numbers placed thereon. 

  

	 	(20)	 GOVERNING LAW. THE INDENTURE AND THIS NOTE, INCLUDING ANY CLAIM OR CONTROVERSY ARISING OUT OF OR RELATED TO THE
INDENTURE OR THIS NOTE, SHALL BE GOVERNED BY THE LAWS OF THE STATE OF NEW YORK. 

 The Company will furnish to any Holder
upon written request and without charge a copy of the Indenture and/or the Officer’s Certificate. 
 Requests may be made
to: 
 Amgen Inc. 
 One
Amgen Center Drive 
 Thousand Oaks, CA 91320-1799 

Attention: Investor Relations 

 ASSIGNMENT FORM 

To assign this Note, fill in the form below: 
  

	
	(I) or (we) assign and transfer this Note to:
                                         
                                   
	 (Insert assignee’s legal name)

	
	  

	(Insert assignee’s soc. sec. or tax I.D. no.)
	
	  

	
	  

	
	  

	
	  

	(Print or type assignee’s name, address and zip code)

 and irrevocably appoint
                                         
                                         
                                         
                                         
             to transfer this Note on the books of the Company. The agent may substitute another to act for him. 

Date:
                                     

 

			
	Your Signature:	 	  

		 	(Sign exactly as your name appears on the face of this Note)

 Signature Guarantee*:
                             

 

	*	 Participant in a recognized Signature Guarantee Medallion Program (or other signature guarantor acceptable to
the Trustee). 

  
  

 Annex C 

Form of 2052 Note 

 [Face of Note] 

 
 CUSIP 031162DF4 

4.200% Senior Notes due 2052 
  

			
	 No. ___
	  	$__________

 AMGEN INC. 

promises to pay to CEDE & CO. or registered assigns, 

the principal sum of ___________ DOLLARS on February 22, 2052. 

Interest Payment Dates: February 22 and August 22 

Record Dates: 15th day prior to February 22 and August 22 

Dated: February 22, 2022 

 
			
	AMGEN INC.
		
	By:	 	  

		 	Name:
		 	Title:

  

			
	This is one of the Notes referred to in the within-mentioned Indenture:
	
	THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., as Trustee
		
	By:	 	  

		 	Authorized Officer

  

			
	Authentication Date:	 	  

  [REVERSE SIDE OF NOTE] 

4.200% SENIOR NOTES DUE 2052 

THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF THE DEPOSITORY
OR A NOMINEE OF THE DEPOSITORY. THIS SECURITY IS EXCHANGEABLE FOR SECURITIES REGISTERED IN THE NAME OF A PERSON OTHER THAN THE DEPOSITORY OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE, AND MAY NOT BE TRANSFERRED EXCEPT
AS A WHOLE BY THE DEPOSITORY TO A NOMINEE OF THE DEPOSITORY, BY A NOMINEE OF THE DEPOSITORY TO THE DEPOSITORY OR ANOTHER NOMINEE OF THE DEPOSITORY OR BY THE DEPOSITORY OR ANY SUCH NOMINEE TO A SUCCESSOR DEPOSITORY OR A NOMINEE OF SUCH A SUCCESSOR
DEPOSITORY. 
 UNLESS THIS CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY TO THE ISSUER OR ITS
AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (AND ANY
PAYMENT HEREON IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL
SINCE THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 
 Capitalized terms used herein have the meanings assigned
to them in the Indenture referred to below unless otherwise indicated. 
  

	 	(1)	 INTEREST. Amgen Inc., a Delaware corporation (the “Company”), promises to pay interest on the
principal amount of this Note at 4.200% per annum from February 22, 2022 until maturity. The Company will pay interest in cash semi-annually in arrears on February 22 and August 22 of each year, or if any such day is not a Business
Day, on the next succeeding Business Day (each, an “Interest Payment Date”). Interest on the Notes will accrue from the most recent date to which interest has been paid or, if no interest has been paid, from the date of issuance;
provided that the first Interest Payment Date shall be August 22, 2022; provided further that after August 22, 2022, if there is no existing Default in the payment of interest, and if this Note is authenticated between a record date
referred to on the face hereof and the next succeeding Interest Payment Date, interest shall accrue from such next succeeding Interest Payment Date. The interest rate will be computed on the basis of a 360-day
year of twelve 30-day calendar months. 

  

	 	(2)	 METHOD OF PAYMENT. The Company will pay interest on the Notes (except defaulted interest) to the Persons who
are registered Holders of Notes at the close of business on the day that is 15 days prior to the next succeeding Interest Payment Date (whether or not such day is a Business Day), even if such Notes are canceled

	 	
after such record date and on or before such Interest Payment Date, except as provided in Section 2.13 of the Indenture with respect to defaulted interest. The Notes will be payable as to
principal and interest at the office or agency of the Company maintained for such purpose in the Borough of Manhattan, the City and State of New York (or, if the Company fails to maintain such office or agency, at the corporate trust office of the
trustee in New York, New York or if the trustee does not maintain an office in New York, at the office of a paying agent in New York), or, at the option of the Company, payment of interest may be made by check mailed to the Holders at their
addresses set forth in the register of Holders; provided that payment by wire transfer of immediately available funds will be required with respect to principal of and interest on all Global Securities and all other Notes the Holders of which
will have provided wire transfer instructions to the Company or the Paying Agent. Such payment will be in the currency of the United States of America. 

  

	 	(3)	 PAYING AGENT AND REGISTRAR. Initially, The Bank of New York Mellon Trust Company, N.A., the Trustee under the
Indenture, will act as Paying Agent and Registrar. The Company may change any Paying Agent or Registrar without notice to any Holder. The Company or any of its Subsidiaries may act in any such capacity. 

 

	 	(4)	 INDENTURE. The terms of the Notes include those stated in the Indenture dated May 22, 2014, between the
Company and the Trustee (the “Indenture”), and those made part of the Indenture by the Officer’s Certificate dated February 22, 2022, delivered pursuant thereto (the “Officer’s Certificate”) and the
TIA. The Notes are subject to all such terms, and the Holders are referred to the Indenture and the TIA for a statement of them. 

  

	 	(5)	 OPTIONAL REDEMPTION. At any time prior to maturity, the Company will have the option to redeem all or a part of
the Notes upon not less than 10 nor more than 60 days’ notice. If the Notes are redeemed before August 22, 2051 (six months prior to the maturity date of the Notes), the redemption price will equal the sum of (1) 100% of the principal
amount of any Notes being redeemed, plus accrued and unpaid interest to, but not including, the redemption date, and (2) the Make-Whole Amount. If the Notes are redeemed on or after August 22, 2051 (six months prior to the maturity date of
the Notes), the redemption price will equal 100% of the principal amount being redeemed, plus accrued and unpaid interest to, but not including, the redemption date. Unless the Company defaults in the payment of the redemption price, interest will
cease to accrue on the Notes or portions thereof called for redemption on the applicable redemption date. 

  

	 	(6)	 NOTICE OF REDEMPTION. Notice of redemption will be mailed at least 10 days but not more than 60 days before the
redemption date to each Holder whose Notes are to be redeemed at its registered address, except that redemption notices may be mailed more than 60 days prior to a redemption date if the notice is issued in connection with a defeasance of the Notes
or a satisfaction or discharge of the Indenture. Notes in denominations larger than $2,000 may be redeemed in part but only in whole multiples of $1,000, unless all of the Notes held by a Holder are to be redeemed. Notices of redemption for the
Notes may be conditional. 

	 	(7)	 MANDATORY REDEMPTION. Except as provided in Section 8 below, the Company is not required to make mandatory
redemption or sinking fund payments with respect to the Notes. 

  

	 	(8)	 CHANGE OF CONTROL TRIGGERING EVENT. In the event of a Change of Control Triggering Event, the Holders may
require the Company to purchase for cash all or a portion of their Notes at a purchase price equal to 101% of the principal amount of the notes, plus accrued and unpaid interest, if any, pursuant to the provisions of Section 7 of the
Officer’s Certificate. If holders of not less than 90% in aggregate principal amount of the outstanding Notes validly tender and do not withdraw such Notes in a Change Of Control Offer and the Company, or any third party making such an offer in
lieu of the Company, purchases all of the Notes validly tendered and not withdrawn by such holders, the Company or such third party will have the right, upon not less than 10 days nor more than 60 days’ prior notice, provided that such notice
is given not more than 30 days following such repurchase pursuant to the Change Of Control Offer described above, to redeem all Notes that remain outstanding following such purchase on a date specified in such notice (the “Second Change Of
Control Payment Date”) and at a price in cash equal to 101% of the aggregate principal amount of Notes repurchased plus any accrued and unpaid interest on the Notes repurchased to, but not including, the Second Change Of Control Payment
Date. 

  

	 	(9)	 DEFEASANCE PRIOR TO MATURITY. The Indenture contains provisions for defeasance of (i) the entire
indebtedness of the Notes or (ii) certain covenants and Events of Default with respect to the Notes, in each case upon compliance with certain conditions set forth therein. 

 

	 	(10)	 RESTRICTIVE COVENANTS. The Indenture and the Officer’s Certificate impose certain limitations on the
Company and its Subsidiaries, including limitations on the Company’s and its Subsidiaries’ ability to create or incur certain Liens on any of their respective properties or assets and to enter into certain sale and lease-back transactions
and on the Company’s ability to engage in mergers or consolidations or the conveyance, transfer or lease of all or substantially all of its properties and assets. These limitations are subject to a number of important qualifications and
exceptions and reference is made to the Indenture and the Officer’s Certificate for a description thereof. 

  

	 	(11)	 DENOMINATIONS, TRANSFER, EXCHANGE. The Notes are in registered form without coupons in denominations of $2,000
and integral multiples of $1,000. The transfer of Notes may be registered and Notes may be exchanged as provided in the Indenture. The Registrar and the Trustee may require a Holder, among other things, to furnish appropriate endorsements and
transfer documents and the Company may require a Holder to pay any taxes and fees required by law or permitted by the Indenture. The Company need not exchange or register the 

	 	
transfer of any Note or portion of a Note selected for redemption, except for the unredeemed portion of any Note being redeemed in part. Also, the Company need not exchange or register the
transfer of any Notes for a period of 15 days before a selection of Notes to be redeemed or during the period between a record date and the corresponding Interest Payment Date. 

 

	 	(12)	 PERSONS DEEMED OWNERS. The registered Holder of a Note may be treated as its owner for all purposes.

  

	 	(13)	 AMENDMENT, SUPPLEMENT AND WAIVER. Subject to certain exceptions, the Indenture or the Notes may be amended or
supplemented with the consent of the Holders of at least a majority in aggregate principal amount of the then outstanding Notes voting as a single class, and any existing Default or Event or Default or compliance with any provision of the Indenture
or the Notes may be waived with the consent of the Holders of a majority in aggregate principal amount of the then outstanding Notes voting as a single class. Without the consent of any Holder of a Note, the Indenture or the Notes may be amended or
supplemented to cure any ambiguity, defect or inconsistency; to comply with Article V of the Indenture; to provide for uncertificated Notes in addition to or in place of certificated Notes; to add guarantees with respect to the Notes or secure the
Notes; to surrender any of the Company’s rights or powers under the Indenture; to add covenants or events of default for the benefit of the Holders of the Notes; to comply with the applicable procedures of the applicable depositary; to make any
change that would not adversely affect the rights under the Indenture of any such Holder in any material respect; to provide for the issuance of and establish the form and terms and conditions of Notes of any series as permitted by the Indenture; to
evidence and provide for the acceptance of appointment under the Indenture by a successor trustee with respect to the Notes and to add to or change any of the provisions of the Indenture necessary to provide for the administration of the trusts in
the Indenture by more than one trustee; or to comply with the requirements of the SEC in order to effect or maintain the qualification of the Indenture under the TIA. No amendment to cure any ambiguity, defect or inconsistency in the Indenture made
solely to conform the Indenture to the description of notes contained in the Prospectus Supplement related to the Notes, dated February 17, 2022, will be deemed to adversely affect the interests of the Holders of the Notes.

  

	 	(14)	 DEFAULTS AND REMEDIES. If an Event of Default shall occur and be continuing, the principal of the Notes may be
declared (or, in certain cases, shall ipso facto become) due and payable in the manner and with the effect provided in the Indenture. 

  

	 	(15)	 TRUSTEE DEALINGS WITH COMPANY. The Trustee under the Indenture, in its individual or any other capacity, may
deal with the Company or an Affiliate of the Company with the same rights it would have if it were not Trustee. 

	 	(16)	 NO RECOURSE AGAINST OTHERS. A director, officer, employee or stockholder of the Company shall not have any
liability for any obligations of the Company under the Notes or the Indenture or for any claim based on, in respect of, or by reason of, such obligations or their creation. Each Holder by accepting a Note waives and releases all such liability. The
waiver and release are part of the consideration for the issuance of the Notes. 

  

	 	(17)	 AUTHENTICATION. This Note will not be valid until authenticated by the manual signature of the Trustee or an
authenticating agent. 

  

	 	(18)	 ABBREVIATIONS. Customary abbreviations may be used in the name of a Holder or an assignee, such as: TEN COM (=
tenants in common), TEN ENT (= tenants by the entireties), JT TEN (= joint tenants with right of survivorship and not as tenants in common), CUST (= Custodian), and U/G/M/A (= Uniform Gifts to Minors Act). 

 

	 	(19)	 CUSIP NUMBERS. Pursuant to a recommendation promulgated by the Committee on Uniform Security Identification
Procedures, the Company has caused CUSIP numbers to be printed on the Notes, and the Trustee may use CUSIP numbers in notices of redemption as a convenience to Holders. No representation is made as to the accuracy of such numbers either as printed
on the Notes or as contained in any notice of redemption, and reliance may be placed only on the other identification numbers placed thereon. 

  

	 	(20)	 GOVERNING LAW. THE INDENTURE AND THIS NOTE, INCLUDING ANY CLAIM OR CONTROVERSY ARISING OUT OF OR RELATED TO THE
INDENTURE OR THIS NOTE, SHALL BE GOVERNED BY THE LAWS OF THE STATE OF NEW YORK. 

 The Company will furnish to any Holder
upon written request and without charge a copy of the Indenture and/or the Officer’s Certificate. 
 Requests may be made
to: 
 Amgen Inc. 
 One
Amgen Center Drive 
 Thousand Oaks, CA 91320-1799 

Attention: Investor Relations 

 ASSIGNMENT FORM 

To assign this Note, fill in the form below: 

(I) or (we) assign and transfer this Note to: ______________________________________________ 

(Insert assignee’s legal name) 
  

 
 (Insert assignee’s soc. sec. or
tax I.D. no.) 
  
  

 
  
  

 
  

 
 (Print or type assignee’s name,
address and zip code) 
 and irrevocably appoint _____________________________________________________________________________________ 

to transfer this Note on the books of the Company. The agent may substitute another to act for him. 

Date: ___________________ 
  

			
	 Your Signature:
	 	  

		 	(Sign exactly as your name appears on the face of this Note)

 Signature Guarantee*: ___________________ 
  

	*	 Participant in a recognized Signature Guarantee Medallion Program (or other signature guarantor acceptable to
the Trustee). 

  
  

 Annex D 

Form of 2062 Note 

 [Face of Note] 

 
 CUSIP 031162DG2 

4.400% Senior Notes due 2062 
  

			
	No. ___	  	$__________

 AMGEN INC. 

promises to pay to CEDE & CO. or registered assigns, 

the principal sum of __________ DOLLARS on February 22, 2062. 

Interest Payment Dates: February 22 and August 22 

Record Dates: 15th day prior to February 22 and August 22 

Dated: February 22, 2022 

 
			
	 AMGEN INC.

		
	 By:
	 	  

		 	 Name:

		 	 Title:

 

			
	This is one of the Notes referred to in the within-mentioned Indenture:
	
	THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., as Trustee
		
	 By:
	 	  

		 	 Authorized Officer

 Authentication Date: _______________________ 

 [REVERSE SIDE OF NOTE] 

4.400% SENIOR NOTES DUE 2062 

THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF THE DEPOSITORY
OR A NOMINEE OF THE DEPOSITORY. THIS SECURITY IS EXCHANGEABLE FOR SECURITIES REGISTERED IN THE NAME OF A PERSON OTHER THAN THE DEPOSITORY OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE, AND MAY NOT BE TRANSFERRED EXCEPT
AS A WHOLE BY THE DEPOSITORY TO A NOMINEE OF THE DEPOSITORY, BY A NOMINEE OF THE DEPOSITORY TO THE DEPOSITORY OR ANOTHER NOMINEE OF THE DEPOSITORY OR BY THE DEPOSITORY OR ANY SUCH NOMINEE TO A SUCCESSOR DEPOSITORY OR A NOMINEE OF SUCH A SUCCESSOR
DEPOSITORY. 
 UNLESS THIS CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY TO THE ISSUER OR ITS
AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (AND ANY
PAYMENT HEREON IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL
SINCE THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 
 Capitalized terms used herein have the meanings assigned
to them in the Indenture referred to below unless otherwise indicated. 
  

	 	(1)	 INTEREST. Amgen Inc., a Delaware corporation (the “Company”), promises to pay interest on the
principal amount of this Note at 4.400% per annum from February 22, 2022 until maturity. The Company will pay interest in cash semi-annually in arrears on February 22 and August 22 of each year, or if any such day is not a Business
Day, on the next succeeding Business Day (each, an “Interest Payment Date”). Interest on the Notes will accrue from the most recent date to which interest has been paid or, if no interest has been paid, from the date of issuance;
provided that the first Interest Payment Date shall be August 22, 2022; provided further that after August 22, 2022, if there is no existing Default in the payment of interest, and if this Note is authenticated between a record date
referred to on the face hereof and the next succeeding Interest Payment Date, interest shall accrue from such next succeeding Interest Payment Date. The interest rate will be computed on the basis of a 360-day
year of twelve 30-day calendar months. 

  

	 	(2)	 METHOD OF PAYMENT. The Company will pay interest on the Notes (except defaulted interest) to the Persons who
are registered Holders of Notes at the close of business on the day that is 15 days prior to the next succeeding Interest Payment Date (whether or not such day is a Business Day), even if such Notes are canceled

	 	
after such record date and on or before such Interest Payment Date, except as provided in Section 2.13 of the Indenture with respect to defaulted interest. The Notes will be payable as to
principal and interest at the office or agency of the Company maintained for such purpose in the Borough of Manhattan, the City and State of New York (or, if the Company fails to maintain such office or agency, at the corporate trust office of the
trustee in New York, New York or if the trustee does not maintain an office in New York, at the office of a paying agent in New York), or, at the option of the Company, payment of interest may be made by check mailed to the Holders at their
addresses set forth in the register of Holders; provided that payment by wire transfer of immediately available funds will be required with respect to principal of and interest on all Global Securities and all other Notes the Holders of which
will have provided wire transfer instructions to the Company or the Paying Agent. Such payment will be in the currency of the United States of America. 

  

	 	(3)	 PAYING AGENT AND REGISTRAR. Initially, The Bank of New York Mellon Trust Company, N.A., the Trustee under the
Indenture, will act as Paying Agent and Registrar. The Company may change any Paying Agent or Registrar without notice to any Holder. The Company or any of its Subsidiaries may act in any such capacity. 

 

	 	(4)	 INDENTURE. The terms of the Notes include those stated in the Indenture dated May 22, 2014, between the
Company and the Trustee (the “Indenture”), and those made part of the Indenture by the Officer’s Certificate dated February 22, 2022, delivered pursuant thereto (the “Officer’s Certificate”) and the
TIA. The Notes are subject to all such terms, and the Holders are referred to the Indenture and the TIA for a statement of them. 

  

	 	(5)	 OPTIONAL REDEMPTION. At any time prior to maturity, the Company will have the option to redeem all or a part of
the Notes upon not less than 10 nor more than 60 days’ notice. If the Notes are redeemed before August 22, 2061 (six months prior to the maturity date of the Notes), the redemption price will equal the sum of (1) 100% of the principal
amount of any Notes being redeemed, plus accrued and unpaid interest to, but not including, the redemption date, and (2) the Make-Whole Amount. If the Notes are redeemed on or after August 22, 2061 (six months prior to the maturity date of
the Notes), the redemption price will equal 100% of the principal amount being redeemed, plus accrued and unpaid interest to, but not including, the redemption date. Unless the Company defaults in the payment of the redemption price, interest will
cease to accrue on the Notes or portions thereof called for redemption on the applicable redemption date. 

  

	 	(6)	 NOTICE OF REDEMPTION. Notice of redemption will be mailed at least 10 days but not more than 60 days before the
redemption date to each Holder whose Notes are to be redeemed at its registered address, except that redemption notices may be mailed more than 60 days prior to a redemption date if the notice is issued in connection with a defeasance of the Notes
or a satisfaction or discharge of the Indenture. Notes in denominations larger than $2,000 may be redeemed in part but only in whole multiples of $1,000, unless all of the Notes held by a Holder are to be redeemed. Notices of redemption for the
Notes may be conditional. 

	 	(7)	 MANDATORY REDEMPTION. Except as provided in Section 8 below, the Company is not required to make mandatory
redemption or sinking fund payments with respect to the Notes. 

  

	 	(8)	 CHANGE OF CONTROL TRIGGERING EVENT. In the event of a Change of Control Triggering Event, the Holders may
require the Company to purchase for cash all or a portion of their Notes at a purchase price equal to 101% of the principal amount of the notes, plus accrued and unpaid interest, if any, pursuant to the provisions of Section 7 of the
Officer’s Certificate. If holders of not less than 90% in aggregate principal amount of the outstanding Notes validly tender and do not withdraw such Notes in a Change Of Control Offer and the Company, or any third party making such an offer in
lieu of the Company, purchases all of the Notes validly tendered and not withdrawn by such holders, the Company or such third party will have the right, upon not less than 10 days nor more than 60 days’ prior notice, provided that such notice
is given not more than 30 days following such repurchase pursuant to the Change Of Control Offer described above, to redeem all Notes that remain outstanding following such purchase on a date specified in such notice (the “Second Change Of
Control Payment Date”) and at a price in cash equal to 101% of the aggregate principal amount of Notes repurchased plus any accrued and unpaid interest on the Notes repurchased to, but not including, the Second Change Of Control Payment
Date. 

  

	 	(9)	 DEFEASANCE PRIOR TO MATURITY. The Indenture contains provisions for defeasance of (i) the entire
indebtedness of the Notes or (ii) certain covenants and Events of Default with respect to the Notes, in each case upon compliance with certain conditions set forth therein. 

 

	 	(10)	 RESTRICTIVE COVENANTS. The Indenture and the Officer’s Certificate impose certain limitations on the
Company and its Subsidiaries, including limitations on the Company’s and its Subsidiaries’ ability to create or incur certain Liens on any of their respective properties or assets and to enter into certain sale and lease-back transactions
and on the Company’s ability to engage in mergers or consolidations or the conveyance, transfer or lease of all or substantially all of its properties and assets. These limitations are subject to a number of important qualifications and
exceptions and reference is made to the Indenture and the Officer’s Certificate for a description thereof. 

  

	 	(11)	 DENOMINATIONS, TRANSFER, EXCHANGE. The Notes are in registered form without coupons in denominations of $2,000
and integral multiples of $1,000. The transfer of Notes may be registered and Notes may be exchanged as provided in the Indenture. The Registrar and the Trustee may require a Holder, among other things, to furnish appropriate endorsements and
transfer documents and the Company may require a Holder to pay any taxes and fees required by law or permitted by the Indenture. The Company need not exchange or register the 

	 	
transfer of any Note or portion of a Note selected for redemption, except for the unredeemed portion of any Note being redeemed in part. Also, the Company need not exchange or register the
transfer of any Notes for a period of 15 days before a selection of Notes to be redeemed or during the period between a record date and the corresponding Interest Payment Date. 

 

	 	(12)	 PERSONS DEEMED OWNERS. The registered Holder of a Note may be treated as its owner for all purposes.

  

	 	(13)	 AMENDMENT, SUPPLEMENT AND WAIVER. Subject to certain exceptions, the Indenture or the Notes may be amended or
supplemented with the consent of the Holders of at least a majority in aggregate principal amount of the then outstanding Notes voting as a single class, and any existing Default or Event or Default or compliance with any provision of the Indenture
or the Notes may be waived with the consent of the Holders of a majority in aggregate principal amount of the then outstanding Notes voting as a single class. Without the consent of any Holder of a Note, the Indenture or the Notes may be amended or
supplemented to cure any ambiguity, defect or inconsistency; to comply with Article V of the Indenture; to provide for uncertificated Notes in addition to or in place of certificated Notes; to add guarantees with respect to the Notes or secure the
Notes; to surrender any of the Company’s rights or powers under the Indenture; to add covenants or events of default for the benefit of the Holders of the Notes; to comply with the applicable procedures of the applicable depositary; to make any
change that would not adversely affect the rights under the Indenture of any such Holder in any material respect; to provide for the issuance of and establish the form and terms and conditions of Notes of any series as permitted by the Indenture; to
evidence and provide for the acceptance of appointment under the Indenture by a successor trustee with respect to the Notes and to add to or change any of the provisions of the Indenture necessary to provide for the administration of the trusts in
the Indenture by more than one trustee; or to comply with the requirements of the SEC in order to effect or maintain the qualification of the Indenture under the TIA. No amendment to cure any ambiguity, defect or inconsistency in the Indenture made
solely to conform the Indenture to the description of notes contained in the Prospectus Supplement related to the Notes, dated February 17, 2022, will be deemed to adversely affect the interests of the Holders of the Notes.

  

	 	(14)	 DEFAULTS AND REMEDIES. If an Event of Default shall occur and be continuing, the principal of the Notes may be
declared (or, in certain cases, shall ipso facto become) due and payable in the manner and with the effect provided in the Indenture. 

  

	 	(15)	 TRUSTEE DEALINGS WITH COMPANY. The Trustee under the Indenture, in its individual or any other capacity, may
deal with the Company or an Affiliate of the Company with the same rights it would have if it were not Trustee. 

	 	(16)	 NO RECOURSE AGAINST OTHERS. A director, officer, employee or stockholder of the Company shall not have any
liability for any obligations of the Company under the Notes or the Indenture or for any claim based on, in respect of, or by reason of, such obligations or their creation. Each Holder by accepting a Note waives and releases all such liability. The
waiver and release are part of the consideration for the issuance of the Notes. 

  

	 	(17)	 AUTHENTICATION. This Note will not be valid until authenticated by the manual signature of the Trustee or an
authenticating agent. 

  

	 	(18)	 ABBREVIATIONS. Customary abbreviations may be used in the name of a Holder or an assignee, such as: TEN COM (=
tenants in common), TEN ENT (= tenants by the entireties), JT TEN (= joint tenants with right of survivorship and not as tenants in common), CUST (= Custodian), and U/G/M/A (= Uniform Gifts to Minors Act). 

 

	 	(19)	 CUSIP NUMBERS. Pursuant to a recommendation promulgated by the Committee on Uniform Security Identification
Procedures, the Company has caused CUSIP numbers to be printed on the Notes, and the Trustee may use CUSIP numbers in notices of redemption as a convenience to Holders. No representation is made as to the accuracy of such numbers either as printed
on the Notes or as contained in any notice of redemption, and reliance may be placed only on the other identification numbers placed thereon. 

  

	 	(20)	 GOVERNING LAW. THE INDENTURE AND THIS NOTE, INCLUDING ANY CLAIM OR CONTROVERSY ARISING OUT OF OR RELATED TO THE
INDENTURE OR THIS NOTE, SHALL BE GOVERNED BY THE LAWS OF THE STATE OF NEW YORK. 

 The Company will furnish to any Holder
upon written request and without charge a copy of the Indenture and/or the Officer’s Certificate. 
 Requests may be made
to: 
 Amgen Inc. 
 One
Amgen Center Drive 
 Thousand Oaks, CA 91320-1799 

Attention: Investor Relations 

 ASSIGNMENT FORM 

To assign this Note, fill in the form below: 

(I) or (we) assign and transfer this Note to: ______________________________________________ 

(Insert assignee’s legal name) 
  

 
 (Insert assignee’s soc. sec. or
tax I.D. no.) 
  
  

 
  
  

 
  

 
 (Print or type assignee’s name,
address and zip code) 
 and irrevocably appoint _____________________________________________________________________________________ 

to transfer this Note on the books of the Company. The agent may substitute another to act for him. 

Date: ___________________ 
  

			
	 Your Signature:
	 	  

		 	(Sign exactly as your name appears on the face of this Note)

 Signature Guarantee*: ___________________ 
  

	*	 Participant in a recognized Signature Guarantee Medallion Program (or other signature guarantor acceptable to
the Trustee).

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