Document:

Exhibit 10.1

 

AMENDMENT NO. 2 TO EXECUTIVE COMPENSATION
AGREEMENT

 

This Amendment
No. 2 to Executive Compensation Agreement (“Amendment No. 2”), dated as of March 10, 2017, and effective
as of January 1, 2017, is made by and between PharmaCyte Biotech, Inc., a Nevada corporation (“Company”),
and Kenneth L. Waggoner (“Executive”). The Company and the Executive are each referred to in this
Amendment No. 2 as a “Party” and collectively as the “Parties.” Capitalized terms used
but not defined in this Amendment No. 2 shall have the meanings given to them in the Executive Compensation Agreement defined
below.

 

RECITALS

 

WHEREAS, The
Parties entered into an Executive Compensation Agreement (“Executive Compensation Agreement”) as of March 10,
2015, effective as of January 1, 2015, as amended by Amendment No. 1, effective as of December 30, 2015, under which the Parties
agreed upon the terms and conditions of the Executive’s employment;

 

WHEREAS, the
Executive Compensation Agreement currently provides that the Company will: (i) pay the Executive an annual base salary of $180,000;
(ii) on an annual basis grant the Executive 2,400,000 shares of restricted Common Stock, vesting at the rate of 200,000 shares
per month; and (iii) on an annual basis grant the Executive an option to purchase 6,000,000 shares of the Company’s restricted
Common Stock per year (“Option”) at the fair market value on the date of grant and vesting at the rate of 500,000 shares
per month, all subject to the Executive providing Services under the Executive Compensation Agreement. The Option is subject to
the terms of a Third Stock Option Agreement;

 

WHEREAS, the
Parties’ desire to extend the Term, amend the terms of the Executive’s compensation and amend the notice provisions
of the Executive Compensation Agreement as set forth in Amendment No. 2.

 

AGREEMENT

 

NOW, THEREFORE, the Parties, intending
to be legally bound, hereby agree as follows:

 

1. The first sentence of Section 1 of
the Executive Compensation Agreement is hereby amended and restated in its entirety as follows:

 

“Effective January 1, 2017, the term of this
Agreement shall extend until December 31, 2018, with annual extensions thereafter unless the Company or the Executive provides
written notice of termination to the other Party at least 90 days prior to the end of the original two-year term or any subsequent
annual extension (the original term, as may be from time to time extended, being referred to as the “Term”).”

 

2. Section 3 (A), (B) and (C) of the
Executive Compensation Agreement is hereby amended and restated to read in its entirety as follows:

 

(A)Base Salary. The Company will pay the
Executive a base salary at an annual rate of $375,000, payable in accordance with the Company’s usual payroll practices.
The Compensation Committee of the Board may increase the base salary annually in its discretion. The annual rate of the Executive’s
base salary as in effect from time to time is referred to herein as “Base Salary.”

 

 

 

 

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(B) Equity Compensation.
Subject to and in consideration of the Executive entering into this Agreement, in March of 2014, the Company granted to the Executive
10,000,000 shares of restricted Common Stock. On the Commencement Date the Company also granted 2,400,000 shares of restricted
Common Stock. On each anniversary of the Commencement Date (so long as this Agreement has not been terminated), the Company shall
issue to the Executive 3,600,000 shares of restricted Common Stock, which shares shall vest at the rate of 300,000 shares per month,
subject to the Executive’s continuing service under this Agreement.

 

(C) Option Awards.
Subject to and in consideration of the Executive entering into this Agreement, on March 24, 2014, the Company granted an option
to purchase 10,000,000 shares of restricted Common Stock (“Option Award”), with a term of five years and an
exercise price equal to the fair market value on the date of grant. The Option Award is governed by the terms of the Stock Option
Agreement between the Parties dated as of March 10, 2015. On the Commencement Date the Company granted to the Executive and option
to purchase 2,400,000 shares of restricted Common Stock ("Second Option Award"), with a term of five years and
an exercise price equal to the fair market value on the date of grant, vesting at the rate of 200,000 shares per month, subject
to the Executive providing Services under this Agreement. The Second Option Award is governed by the terms of the Second Stock
Option Agreement between the Parties dated as of March 10, 2015. On December 30, 2015, the Company granted to the Executive an
option to purchase 6,000,000 shares of restricted Common Stock ("Third Option Award"), with a term of five years
and an exercise price of $0.063, representing the fair market value on the date of grant and vesting at the rate of 500,000 shares
per month, commencing January 1, 2016, subject to the Executive providing Services under this Agreement. The Third Option Award
is governed by the terms of the Third Stock Option Agreement between the Parties dated as of December 30, 2015. On each anniversary
of the Commencement Date (so long as this Agreement has not been terminated), the Company shall grant to the Executive an option
to purchase 4,500,000 shares of restricted Common Stock ("New Option Awards"), with a term of five years and an
exercise price of $0.1040, representing the fair market value on the date of grant and vesting at the rate of 375,000 shares per
month, commencing January 1, 2017, subject to the Executive providing Services under this Agreement. The New Option Awards shall
be governed by the terms of the Fourth Stock Option Agreement between the Parties in substantially the form attached hereto as
Exhibit A.

 

3. The addresses
for notices set forth in Section 12 of the Executive Compensation Agreement are hereby replaced with the following addresses:

 

To the Executive:

25422 Trabuco Road, Suite 105

Lake Forest, California 92630

Email: kwaggoner@PharmaCyte.com

Fax No.: (917) 595-2851

 

To the Company:

23046 Avenida de la Carlota, Suite
600

Laguna Hills, California 92653

Email: ctrujillo@PharmaCyte.com

Fax No.: (917) 595-2851

 

 

 

 

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4.Except as specifically
provided in and modified by this Amendment No. 2, the Executive Compensation Agreement is in all respects hereby ratified and confirmed.
All references to the “Agreement” or the “Executive Compensation Agreement” shall be deemed to refer to
the Executive Compensation Agreement as such document has been modified by this Amendment No. 2, including, without limitation,
references to the “Agreement” in Section 13 of the Executive Compensation Agreement.

 

5.The provisions
of Section 11 and Section 19 of the Executive Compensation Agreement shall apply to this Amendment No. 2 as if set forth in full
in this Amendment No. 2, mutatis mutandis, and are hereby incorporated by reference in this Amendment No. 2.

 

6. This Amendment
No. 2 may be executed in two or more counterparts, each of which shall be deemed an original, but all of which taken together shall
constitute one and the same instrument. Signatures delivered by facsimile or electronic mail, including by PDF, shall be effective
as original signatures for all purposes.

 

IN WITNESS WHEREOF,
the undersigned have executed this Amendment No. 2 on the day and year first written above.

 

 

 

	 	PHARMACYTE BIOTECH, INC.
	 	 	 
	 	By: 	/s/ Carlos A. Trujillo
	 	Name: Carlos A. Trujillo
	 	Title: Chief Financial Officer
	 	 	 
	 	 	 
	 	EXECUTIVE
	 	 	 
	 	By:	/s/ Kenneth L. Waggoner
	 	Name: Kenneth L. Waggoner
	 	Title: Chief Executive Officer
	 	President and General Counsel

 

 

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Exhibit A

 

FOURTH
STOCK OPTION AGREEMENT

 

This Fourth Stock Option
Agreement (“Agreement”) is made as of the 10th day of March, 2017 by and between PharmaCyte Biotech,
Inc. (“Company”) and Kenneth L. Waggoner (“Participant”).

 

1.                 
Award. On March 9, 2017 (“Grant Date”), the Company granted to the Participant an option (“Option”)
to purchase 4,500,000 shares of the Company’s common stock (“Common Stock”), par value $0.0001 per share
(“Share” or “Shares”), subject to the terms and conditions of this Agreement. The purchase
price per Share (“Exercise Price”) is $0.1040, which represents the fair market value of each Share on the Grant
Date. This grant is in satisfaction of the Company’s obligation to the Participant with respect to the Fourth Option Award
provided for in the Executive Compensation Agreement by and between the Company and the Participant entered into as of March 10,
2015, effective as of January 1, 2015, as amended by Amendment No. 1 to Executive Compensation Agreement dated December 30, 2015
and by Amendment No. 2 to Executive Compensation Agreement dated March 10, 2017 (“Executive Compensation Agreement”).

 

2.                 
Incentive Stock Option Status. The Option is not intended to be treated as an “incentive stock option”
within the meaning of Section 422 of the Internal Revenue Code of 1986.

 

3.                 
Option Term. Unless terminated sooner in accordance with this Agreement, the Option shall expire if and to the extent
it is not exercised within five years from the Grant Date.

 

4.                 
Vesting of Option. Subject to the provisions hereof, the Option shall vest at the rate of 375,000 Shares per month,
subject to Participant’s continuing service under the Executive Compensation Agreement.

 

5.                 
Forfeiture Events. If a “Forfeiture Event” occurs, then, to the extent not previously exercised, this
Agreement shall thereupon terminate and be of no further force or effect. For the purposes of this Agreement, the term “Forfeiture
Event” means any of the following events: (i) termination of the Executive Compensation Agreement for Cause; or (ii)
the failure by Participant to provide or be available to provide post-termination consulting services as and to the extent such
availability and/or services are reasonably required by the Executive Compensation Agreement.

 

6.                 
Exercise Procedures. The Participant may exercise the Option by transmitting to the Secretary of the Company (or
another person designated by the Company for this purpose) a written notice specifying the number of whole Shares to be purchased
pursuant to such exercise, together with payment in full of the aggregate Exercise Price payable for such Shares and the amount
of applicable withholding taxes and execution and/or delivery of such representations, releases and other documents as the Board
of Directors of the Company (“Board”) may prescribe. The Exercise Price and the minimum required tax withholding
amount shall be payable in cash or by check; provided, however, at the Participant’s request and subject to the provisions
of applicable law, the Participant may satisfy such payments (in whole or in part): (i) by the Participant’s surrender of
previously-owned Shares or by the Company’s withholding Shares that otherwise would be issued if the Exercise Price had been
paid in cash, according to the formula below:

 

	 	X =	(A-B)(Y)

       A
	 	 	 
	Where	X =	the number of Shares to be issued to the Participant.
	 	Y =	the number of Shares issuable upon exercise of this Option, assuming
a cash exercise
	 	A =	Fair Market Value
	 	B =	the Exercise Price

 

 

 

 

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in each case having a “Fair Market
Value” (as defined below) on the date the Option is exercised equal to the amount of the Exercise Price and/or tax withholding
obligation that is being satisfied with such Shares; (ii) by payment to the Company pursuant to a broker-assisted cashless exercise
program arrangement that may be made available by the Company; or (iii) by any combination of the foregoing. For this purpose,
“Fair Market Value” means, as of any relevant date, the value of the Company’s Shares determined as follows:
(a) if the Shares are admitted to trading on a “national securities exchange” (as defined under the Securities Exchange
Act of 1934, as amended) on such date, the closing price per Share on such date on the principal national securities exchange on
which the Shares are traded or, if no Shares are traded on that date, the closing price per Share on the next preceding date on
which Shares are traded; (b) if the Shares are not admitted to trading on a national securities exchange on such date but are traded
on the electronic quotation system operated by OTC Markets Group, Inc. (“OTCQB”), the last closing price for a Share
as reported by the OTCQB (or similar organization or agency succeeding to its functions of reporting prices) at the close of business
on such date, or if there is no closing price on such date, then the closing bid price on such date; or (c) if the Shares are not
listed on a national securities exchange or traded on the OTCQB or other service, the fair market value per Share as determined
by the Board, acting in its discretion in accordance with the requirements of applicable tax law.

 

7.                 
Adjustments for Capital Changes. The Exercise Price and the number of Shares purchasable upon the exercise of this
Option shall be subject to adjustment from time to time as set forth in this Section 7. The Company shall give Participant notice
of any event described below which requires an adjustment pursuant to this Section 7 in accordance with the notice provisions set
forth in Section 7(e).

 

(a)               
Stock Splits, etc. The number of Shares purchasable upon the exercise of this Option and the Exercise Price shall
be subject to adjustment from time to time upon the happening of any of the following: In case the Company shall: (i) pay a dividend
in Shares or make a distribution in Shares to holders of its outstanding Shares; (ii) subdivide its outstanding Shares into a greater
number of Shares; (iii) combine its outstanding Shares into a smaller number of Shares; or (iv) issue any Shares in a reclassification
of the Shares, then the number of Shares purchasable upon exercise of this Option immediately prior thereto shall be adjusted so
that the Participant shall be entitled to receive the kind and number of Shares or other securities which it would have owned or
have been entitled to receive had such Option been exercised in advance thereof. Upon each such adjustment of the kind and number
of Shares or other securities of the Company which are purchasable hereunder, the Participant shall thereafter be entitled to purchase
the number of Shares or other securities resulting from such adjustment at an Exercise Price per Share or other security obtained
by multiplying the Exercise Price in effect immediately prior to such adjustment by the number of Shares purchasable pursuant hereto
immediately prior to such adjustment and dividing by the number of Shares or other securities of the Company that are purchasable
pursuant hereto immediately thereafter. An adjustment made pursuant to this paragraph shall become effective immediately after
the effective date of such event retroactive to the record date, if any, for such event.

 

(b)              
Recapitalization, Reorganization, Reclassification, Consolidation, Merger or Sale. In case the Company shall reorganize
its capital, reclassify its capital stock, consolidate or merge with or into another corporation (where the Company is not the
surviving corporation or where there is a change in or distribution with respect to the Shares of the Company), or sell, transfer
or otherwise dispose of any of its property, assets or business to another corporation and, pursuant to the terms of such reorganization,
reclassification, merger, consolidation or disposition of assets, shares of common stock of the successor or acquiring corporation,
or any cash, shares of stock or other securities or property of any nature whatsoever (including warrants or other subscription
or purchase rights) in addition to or in lieu of common stock of the successor or acquiring corporation (“Other Property”),
are to be received by or distributed to the holders of the Company, then the Participant shall have the right thereafter to receive,
upon exercise of this Option, the number of shares of common stock of the successor or acquiring corporation or of the Company’s
Shares, if it is the surviving corporation, and Other Property receivable upon or as a result of such reorganization, reclassification,
merger, consolidation or disposition of assets by the Participant of the number of Shares of for which this Option is exercisable
immediately prior to such event. In case of any such reorganization, reclassification, merger, consolidation or disposition of
assets, the successor or acquiring corporation (if other than the Company) shall expressly assume the due and punctual observance
and performance of each and every covenant and condition of this Option to be performed and observed by the Company and all the
obligations and liabilities hereunder, subject to such modifications as may be deemed appropriate (as determined in good faith
by resolution of the Board of the Company) in order to provide for adjustments of Shares for which this Option is exercisable which
shall be as nearly equivalent as practicable to the adjustments provided for in this Section 7 of this Option. For purposes of
this Section 7(b), “common stock of the successor or acquiring corporation” shall include stock of such corporation
of any class which is not preferred as to dividends or assets over any other class of stock of such corporation and which is not
subject to redemption and shall also include any evidences of indebtedness, shares of stock or other securities which are convertible
into or exchangeable for any such stock, either immediately or upon the arrival of a specified date or the happening of a specified
event and any warrants or other rights to subscribe for or purchase any such stock. The foregoing provisions of this Section 7
shall similarly apply to successive reorganizations, reclassifications, mergers, consolidations or disposition of assets.

 

 

 

 

 

    	 	5	 

     

    

 

(c)               
Adjustment for Other Dividends and Distributions. If the Company shall, at any time or from time to time, make or
issue or set a record date for the determination of holders entitled to receive a dividend or other distribution payable in: (i)
cash; (ii) any evidences of indebtedness, or any other securities of the Company or any property of any nature whatsoever, other
than, in each case, Shares; or (iii) any warrants or other rights to subscribe for or purchase any evidences of indebtedness, or
any other securities of the Company or any property of any nature whatsoever, other than, in each case, Shares, then, and in each
event, (A) the number of Shares for which this Option shall be exercisable shall be adjusted to equal the product of the number
of Shares for which this Option is exercisable immediately prior to such adjustment multiplied by a traction (1) the numerator
of which shall be the Fair Market Value of the Shares at the date of taking such record and (2) the denominator of which shall
be such Fair Market Value of the Shares minus the amount allocable to one Share of any such cash so distributable and of the fair
value (as determined in good faith by the Board) of any and all such evidences of indebtedness, Shares, other securities or property
or warrants or other subscription or purchase rights so distributable, and (B) the Exercise Price then in effect shall be adjusted
to equal (1) the Exercise Price then in effect multiplied by the number of Shares for which this Option is exercisable immediately
prior to the adjustment divided by (2) the number of Shares for which this Option is exercisable immediately after such adjustment.
A rectification of the Shares (other than a change in par value, or from par value to no par value or from no par value to par
value) into Shares and shares of any other class of stock shall be deemed a distribution by the Company to the holders of such
Shares of such other class of shares within the meaning of this Section 7(c) and, if the outstanding Shares shall be changed into
a larger or smaller number of Shares as a part of such reclassification, such change shall be deemed a subdivision or combination,
as the case may be, of the outstanding Shares within the meaning of Section 7(a).

 

(d)              
Form of Option after Adjustments. The form of this Option need not be changed because of any adjustments in the Exercise
Price or the number and kind of securities purchasable upon the exercise of this Option.

 

(e)               
Notice of Adjustments. Whenever the number of Shares or number or kind of securities or other property purchasable
upon the exercise of this Option or the Exercise Price is adjusted, as herein provided, the Company shall give notice thereof to
the Participant, which notice shall state the number of Shares (and other securities or property) purchasable upon the exercise
of this Option and the Exercise Price of such Shares (and other securities or property) after such adjustment, setting forth a
brief statement of the facts requiring such adjustment and setting forth the computation by which such adjustment was made.

 

8.                 
Transfer Restrictions. Except as may otherwise be expressly permitted by the Board, the Option is not assignable
or transferable other than to a beneficiary designated to receive the Option upon the Participant’s death or by will or the
laws of descent and distribution, and the Option shall be exercisable during the lifetime of the Participant only by the Participant
(or, in the event of the Participant’s incapacity, the Participant’s legal representative or guardian). Any attempt
by the Participant or any other person claiming against, through or under the Participant to cause the Option or any part of it
to be transferred or assigned in any manner and for any purpose not permitted under this Agreement shall be null and void and without
effect ab initio.

 

 

 

 

    	 	6	 

     

    

 

9.                 
Rights as a Stockholder. No Shares shall be sold, issued or delivered pursuant to the exercise of the Option until
full payment for such Shares has been made or provided for (including, for this purpose, satisfaction of all applicable withholding
taxes). The Participant shall have no rights as a stockholder with respect to any Shares covered by the Option unless and until
the Option is exercised and the Shares purchased pursuant to such exercise are issued in the name of the Participant. Except as
otherwise specified, no adjustment shall be made for dividends or distributions of other rights for which the record date is prior
to the date such Shares are issued.

 

10.             
Tax Withholding. The Company’s obligation to issue Shares pursuant to the exercise of the Option shall be subject
to and conditioned upon the satisfaction by the Participant of applicable tax withholding obligations in accordance with Section
6 of this Agreement. If and to the extent the applicable withholding obligations is payable in cash, the Participant hereby authorizes
the Company to satisfy all or part of such tax withholding obligations by deductions from cash compensation or other payments that
would otherwise be owed to the Participant.

 

11.             
No Other Rights Conferred. Nothing contained herein shall be deemed to give the Participant a right to be retained
in the employ or other service of the Company or any affiliate or to affect the right of the Company and its affiliates to terminate,
or modify the terms and conditions of, the Participant’s employment or other service.

 

12.             
Successors. This Agreement shall be binding upon and shall inure to the benefit of the parties hereto and their respective
successors and permitted assigns.

 

13.             
Entire Agreement. This Agreement constitutes the entire agreement between the parties with respect to the subject
matter hereof and may not be modified except by written instrument executed by the parties.

 

14.             
Governing Law. This Agreement shall be governed by the laws of the State of Nevada, without regard to its principles
of conflict of laws.

 

15.             
Counterparts; Electronic Execution. This Agreement may be executed in separate counterparts, each of which will be
an original and all of which taken together shall constitute one and the same agreement. Signatures delivered by facsimile or electronic
mail, including by PDF, shall be effective as original signatures for all purposes.

 

The undersigned have
executed this Agreement as of the first date set forth above.

 

	 	PharmaCyte Biotech, Inc.
	 	 	 
	 	By: 	
	 	Name: Carlos A. Trujillo
	 	Title: Chief Financial Officer
	 	 	 
	 	 	 
	 	Participant
	 	 	 
	 	By:	
	 	Name: Kenneth L. Waggoner

 

 

 

 

 

 

 

 

    	 	7EXHIBIT 10.2

 

AMENDMENT
No. 2 TO executive Compensation AGREEMENT

 

This Amendment No.
2 to Executive Compensation Agreement (“Amendment No. 2”) dated as of March 10, 2017, is made by and between
PharmaCyte Biotech, Inc., a Nevada corporation (“Company”), and Carlos A. Trujillo (“Executive”).
The Company and the Executive are each referred to in this Amendment No. 2 as a “Party” and collectively as
the “Parties.” Capitalized terms used but not defined in this Amendment No. 2 shall have the meanings given
to them in the Executive Compensation Agreement defined below.

 

RECITALS

 

WHEREAS, the
Parties entered into an Employment Agreement (“Executive Compensation Agreement”) as of March 10, 2015, effective
as of January 1, 2015, as amended by Amendment No. 1, effective as of December 30, 2015, under which the Parties agreed upon the
terms and conditions of the Executive’s employment;

 

WHEREAS, the
Executive Compensation Agreement currently provides that the Company will: (i) pay the Executive an annual base salary of $156,000;
(ii) on an annual basis grant the Executive 1,200,000 shares of restricted Common Stock, vesting at the rate of 100,000 shares
per month; and (iii) on an annual basis grant the Executive an option to purchase 4,800,000 shares of the Company’s restricted
Common Stock per year (“Option”) at the fair market value on the date of grant and vesting at the rate of 400,000 shares
per month, all subject to the Executive providing Services under the Executive Compensation Agreement. The Option is subject to
the terms of a Second Stock Option Agreement;

 

WHEREAS, the
Parties’ desire to extend the Term, amend the terms of the Executive’s compensation and amend the notice provisions
of the Executive Compensation Agreement as set forth in this Amendment No. 2.

 

AGREEMENT

 

NOW, THEREFORE,
the Parties, intending to be legally bound, hereby agree as follows:

 

1.The first sentence
of Section 1 of the Executive Compensation Agreement is hereby amended and restated to read in its entirety as follows:

 

“TERM.
Effective January 1, 2017, the term of this Agreement shall extend until December 31, 2018, with annual extensions thereafter
unless the Company or the Executive provides written notice of termination to the other Party at least 90 days prior to the end
of the original two-year term or any subsequent annual extension (the original term, as may be from time to time extended, being
referred to as the “Term”).”

 

2.The second
paragraph of Section 1 of the Executive Compensation Agreement is hereby amended and restated to read in its entirety as follows:

 

 

 

 

    	 	1	 

     

    

 

POSITION;
DUTIES. The Executive shall be employed as: (i) a member of the Company’s Board of Directors (“Board”);
(ii) Chief Financial Officer of the Company; and (iii) Chief Financial Officer of Viridis Biotech, Inc. and shall have the authorities
and responsibilities customarily associated with the status of such positions at NASDAQ listed companies. In his capacity as Chief
Financial Officer, the Executive shall report directly to the Chief Executive Officer of the Company and shall have responsibility
for all the Company’s financial operations in the U.S. and abroad. Upon termination of the Executive’s employment for
any reason, if and to the extent requested by the Company, the Executive shall promptly resign from the Board and from all other
positions that the Executive then holds with the Company or any affiliate and promptly execute all documentation for such resignations.

 

3.Section 3. (A),
(B) and (C) of the Executive Compensation Agreement is hereby amended and restated to read in its entirety as follows:

 

(A) Base Salary. The
Company will pay the Executive a base salary at an annual rate of $275,000, payable in accordance with the Company’s usual
payroll practices. The Compensation Committee of the Board may increase the base salary annually in its discretion. The annual
rate of the Executive’s base salary as in effect from time to time is referred to herein as “Base Salary.”

 

(B) Equity Compensation.
Subject to and in consideration of the Executive entering into this Agreement, on the Commencement Date and each anniversary of
the Commencement Date (so long as this Agreement has not been terminated), the Company shall issue to the Executive 2,400,000 shares
of restricted Common Stock, which shares shall vest at the rate of 200,000 shares per month, subject to Executive’s continuing
service under this Agreement.

 

(C) Option
Awards. On the Commencement Date, the Company granted to the Executive an option to purchase 2,400,000 shares of Common Stock
("Initial Option Award"), with a term of five years and an exercise price equal to the fair market value on the
date of grant, vesting at the rate of 200,000 shares per month, subject to the Executive providing Services under this Agreement.
The Initial Option Award is governed by the terms of the Stock Option Agreement between the Parties dated as of March 10, 2015.
On December 30, 2015, the Company granted to the Executive an option to purchase 4,800,000 shares of Common Stock ("Second
Option Award"), with a term of five years and an exercise price of $0.063, representing the fair market value on the date
of grant and vesting at the rate of 400,000 shares per month, subject to the Executive providing Services under this Agreement.
The Second Option Award is governed by the terms of the Second Stock Option Agreement between the Parties dated as of December
30, 2015. On each anniversary of the Commencement Date (so long as this Agreement has not been terminated), the Company shall grant
to the Executive a stock option to purchase 3,000,000 shares of Common Stock ("New Option Awards"), with a term
of five years and an exercise price of $0.1040, representing the fair market value on the date of grant, and vesting at the rate
of 250,000 shares per month, commencing January 1, 2017, subject to the Executive providing Services under this Agreement. The
New Option Awards shall be governed by the terms of a Third Stock Option Agreement between the Parties in substantially the form
attached hereto as Exhibit A.

 

 

 

 

 

 

    	 	2	 

     

    

 

4.The addresses
for notices set forth in Section 11 of the Executive Compensation Agreement are hereby replaced with the following addresses:

 

To the Executive:

34145 Pacific Coast Highway, No. 357

Dana Point, California 92629

Email: ctrujillo@PharmaCyte.com

Fax No.: (917) 595-2851

 

To the Company:

23046 Avenida de la Carlota, Suite 600

Laguna Hills, California 92653

Attention: Kenneth L. Waggoner

Chief Executive Officer

Email: kwaggoner@PharmaCyte.com

Fax No.: (917) 595-2851

 

5.Except as specifically
provided in and modified by this Amendment No. 2, the Executive Compensation Agreement is in all respects hereby ratified and confirmed.
All references to the “Agreement” or the Executive Compensation Agreement shall be deemed to refer to the Executive
Compensation Agreement as such document has been modified by this Amendment No. 2, including, without limitation, references to
the “Agreement” in Section 12 of the Executive Compensation Agreement.

 

6. The provisions
of Section 10 and Section 18 of the Executive Compensation Agreement shall apply to this Amendment No. 2 as if set forth in full
in this Amendment No. 2, mutatis mutandis, and are hereby incorporated by reference in this Amendment No. 2.

 

7.This Amendment No. 2 may be executed
in two or more counterparts, each of which shall be deemed an original, but all of which taken together shall constitute one and
the same instrument. Signatures delivered by facsimile or electronic mail, including by PDF, shall be effective as original signatures
for all purposes.

 

 

 

 

 

[Signature page follows]

 

 

 

 

 

    	 	3	 

     

    

 

IN WITNESS WHEREOF,
the undersigned have executed this Amendment on the day and year first written above.

 

 

	 	PHARMACYTE BIOTECH, INC.
	 	 	 
	 	By: 	/s/ Kenneth L. Waggoner
	 	Name: Kenneth L. Waggoner
	 	Title: Chief Executive Officer
	 	 	 
	 	 	 
	 	EXECUTIVE
	 	 	 
	 	By:	/s/ Carlos A. Trujillo
	 	Name: Carlos A. Trujillo
	 	Title: Chief Financial Officer

 

 

 

 

 

 

    	 	4	 

     

    

 

Exhibit A

 

Third
STOCK OPTION AGREEMENT

 

This Third Stock Option
Agreement (“Agreement”) is made as of the 10th day of March, 2017 by and between PharmaCyte Biotech,
Inc. (“Company”) and Carlos A. Trujillo (“Participant”).

 

1.                 
Award. On March 9, 2017 (“Grant Date”), the Company granted to the Participant an option (“Option”)
to purchase 3,000,000 shares of the Company’s common stock (“Common Stock”), par value $0.0001 per share
(“Share” or “Shares”), subject to the terms and conditions of this Agreement. The purchase
price per Share (“Exercise Price”) is $0.1040, which represents the fair market value of each Share on the Grant
Date. This grant is in satisfaction of the Company’s obligation to the Participant with respect to the Third Option Award
provided for in the Executive Compensation Agreement by and between the Company and the Participant entered into as of March 10,
2015, effective as of January 1, 2015, as amended by Amendment No. 1 to Executive Compensation Agreement dated December 30, 2015
and by Amendment No. 2 to Executive Compensation Agreement dated March 10, 2017 (“Executive Compensation Agreement”).

 

2.                 
Incentive Stock Option Status. The Option is not intended to be treated as an “incentive stock option”
within the meaning of Section 422 of the Internal Revenue Code of 1986.

 

3.                 
Option Term. Unless terminated sooner in accordance with this Agreement, the Option shall expire if and to the extent
it is not exercised within five years from the Grant Date.

 

4.                 
Vesting of Option. Subject to the provisions hereof, the Option shall vest at the rate of 250,000 Shares per month,
subject to Participant’s continuing service under the Executive Compensation Agreement.

 

5.                 
Forfeiture Events. If a “Forfeiture Event” occurs, then, to the extent not previously exercised, this
Agreement shall thereupon terminate and be of no further force or effect. For the purposes of this Agreement, the term “Forfeiture
Event” means any of the following events: (i) termination of the Executive Compensation Agreement for Cause; or (ii)
the failure by Participant to provide or be available to provide post-termination consulting services as and to the extent such
availability and/or services are reasonably required by the Executive Compensation Agreement.

 

6.                 
Exercise Procedures. The Participant may exercise the Option by transmitting to the Secretary of the Company (or
another person designated by the Company for this purpose) a written notice specifying the number of whole Shares to be purchased
pursuant to such exercise, together with payment in full of the aggregate Exercise Price payable for such Shares and the amount
of applicable withholding taxes and execution and/or delivery of such representations, releases and other documents as the Board
of Directors of the Company (“Board”) may prescribe. The Exercise Price and the minimum required tax withholding
amount shall be payable in cash or by check; provided, however, at the Participant’s request and subject to the provisions
of applicable law, the Participant may satisfy such payments (in whole or in part): (i) by the Participant’s surrender of
previously-owned Shares or by the Company’s withholding Shares that otherwise would be issued if the Exercise Price had been
paid in cash, according to the formula below:

  

	 	X =	(A-B)(Y)

       A
	 	 	 
	Where	X =	the number of Shares to be issued to the Participant.
	 	Y =	the number of Shares issuable upon exercise of this Option, assuming
a cash exercise
	 	A =	Fair Market Value
	 	B =	the Exercise Price

 

 

 

    	 	5	 

     

    

 

in each case having a “Fair Market
Value” (as defined below) on the date the Option is exercised equal to the amount of the Exercise Price and/or tax withholding
obligation that is being satisfied with such Shares; (ii) by payment to the Company pursuant to a broker-assisted cashless exercise
program arrangement that may be made available by the Company; or (iii) by any combination of the foregoing. For this purpose,
“Fair Market Value” means, as of any relevant date, the value of the Company’s Shares determined as follows:
(a) if the Shares are admitted to trading on a “national securities exchange” (as defined under the Securities Exchange
Act of 1934, as amended) on such date, the closing price per Share on such date on the principal national securities exchange on
which the Shares are traded or, if no Shares are traded on that date, the closing price per Share on the next preceding date on
which Shares are traded; (b) if the Shares are not admitted to trading on a national securities exchange on such date but are traded
on the electronic quotation system operated by OTC Markets Group, Inc. (“OTCQB”), the last closing price for a Share
as reported by the OTCQB (or similar organization or agency succeeding to its functions of reporting prices) at the close of business
on such date, or if there is no closing price on such date, then the closing bid price on such date; or (c) if the Shares are not
listed on a national securities exchange or traded on the OTCQB or other service, the fair market value per Share as determined
by the Board, acting in its discretion in accordance with the requirements of applicable tax law.

 

7.                 
Adjustments for Capital Changes. The Exercise Price and the number of Shares purchasable upon the exercise of this
Option shall be subject to adjustment from time to time as set forth in this Section 7. The Company shall give Participant notice
of any event described below which requires an adjustment pursuant to this Section 7 in accordance with the notice provisions set
forth in Section 7(e).

 

(a)               
Stock Splits, etc. The number of Shares purchasable upon the exercise of this Option and the Exercise Price shall
be subject to adjustment from time to time upon the happening of any of the following: In case the Company shall: (i) pay a dividend
in Shares or make a distribution in Shares to holders of its outstanding Shares; (ii) subdivide its outstanding Shares into a greater
number of Shares; (iii) combine its outstanding Shares into a smaller number of Shares; or (iv) issue any Shares in a reclassification
of the Shares, then the number of Shares purchasable upon exercise of this Option immediately prior thereto shall be adjusted so
that the Participant shall be entitled to receive the kind and number of Shares or other securities which it would have owned or
have been entitled to receive had such Option been exercised in advance thereof. Upon each such adjustment of the kind and number
of Shares or other securities of the Company which are purchasable hereunder, the Participant shall thereafter be entitled to purchase
the number of Shares or other securities resulting from such adjustment at an Exercise Price per Share or other security obtained
by multiplying the Exercise Price in effect immediately prior to such adjustment by the number of Shares purchasable pursuant hereto
immediately prior to such adjustment and dividing by the number of Shares or other securities of the Company that are purchasable
pursuant hereto immediately thereafter. An adjustment made pursuant to this paragraph shall become effective immediately after
the effective date of such event retroactive to the record date, if any, for such event.

 

(b)              
Recapitalization, Reorganization, Reclassification, Consolidation, Merger or Sale. In case the Company shall reorganize
its capital, reclassify its capital stock, consolidate or merge with or into another corporation (where the Company is not the
surviving corporation or where there is a change in or distribution with respect to the Shares of the Company), or sell, transfer
or otherwise dispose of any of its property, assets or business to another corporation and, pursuant to the terms of such reorganization,
reclassification, merger, consolidation or disposition of assets, shares of common stock of the successor or acquiring corporation,
or any cash, shares of stock or other securities or property of any nature whatsoever (including warrants or other subscription
or purchase rights) in addition to or in lieu of common stock of the successor or acquiring corporation (“Other Property”),
are to be received by or distributed to the holders of the Company, then the Participant shall have the right thereafter to receive,
upon exercise of this Option, the number of shares of common stock of the successor or acquiring corporation or of the Company’s
Shares, if it is the surviving corporation, and Other Property receivable upon or as a result of such reorganization, reclassification,
merger, consolidation or disposition of assets by the Participant of the number of Shares of for which this Option is exercisable
immediately prior to such event. In case of any such reorganization, reclassification, merger, consolidation or disposition of
assets, the successor or acquiring corporation (if other than the Company) shall expressly assume the due and punctual observance
and performance of each and every covenant and condition of this Option to be performed and observed by the Company and all the
obligations and liabilities hereunder, subject to such modifications as may be deemed appropriate (as determined in good faith
by resolution of the Board of the Company) in order to provide for adjustments of Shares for which this Option is exercisable which
shall be as nearly equivalent as practicable to the adjustments provided for in this Section 7 of this Option. For purposes of
this Section 7(b), “common stock of the successor or acquiring corporation” shall include stock of such corporation
of any class which is not preferred as to dividends or assets over any other class of stock of such corporation and which is not
subject to redemption and shall also include any evidences of indebtedness, shares of stock or other securities which are convertible
into or exchangeable for any such stock, either immediately or upon the arrival of a specified date or the happening of a specified
event and any warrants or other rights to subscribe for or purchase any such stock. The foregoing provisions of this Section 7
shall similarly apply to successive reorganizations, reclassifications, mergers, consolidations or disposition of assets.

 

 

 

    	 	6	 

     

    

 

(c)               
Adjustment for Other Dividends and Distributions. If the Company shall, at any time or from time to time, make or
issue or set a record date for the determination of holders entitled to receive a dividend or other distribution payable in: (i)
cash; (ii) any evidences of indebtedness, or any other securities of the Company or any property of any nature whatsoever, other
than, in each case, Shares; or (iii) any warrants or other rights to subscribe for or purchase any evidences of indebtedness, or
any other securities of the Company or any property of any nature whatsoever, other than, in each case, Shares, then, and in each
event, (A) the number of Shares for which this Option shall be exercisable shall be adjusted to equal the product of the number
of Shares for which this Option is exercisable immediately prior to such adjustment multiplied by a traction (1) the numerator
of which shall be the Fair Market Value of the Shares at the date of taking such record and (2) the denominator of which shall
be such Fair Market Value of the Shares minus the amount allocable to one Share of any such cash so distributable and of the fair
value (as determined in good faith by the Board) of any and all such evidences of indebtedness, Shares, other securities or property
or warrants or other subscription or purchase rights so distributable, and (B) the Exercise Price then in effect shall be adjusted
to equal (1) the Exercise Price then in effect multiplied by the number of Shares for which this Option is exercisable immediately
prior to the adjustment divided by (2) the number of Shares for which this Option is exercisable immediately after such adjustment.
A rectification of the Shares (other than a change in par value, or from par value to no par value or from no par value to par
value) into Shares and shares of any other class of stock shall be deemed a distribution by the Company to the holders of such
Shares of such other class of shares within the meaning of this Section 7(c) and, if the outstanding Shares shall be changed into
a larger or smaller number of Shares as a part of such reclassification, such change shall be deemed a subdivision or combination,
as the case may be, of the outstanding Shares within the meaning of Section 7(a).

 

(d)              
Form of Option after Adjustments. The form of this Option need not be changed because of any adjustments in the Exercise
Price or the number and kind of securities purchasable upon the exercise of this Option.

 

(e)               
Notice of Adjustments. Whenever the number of Shares or number or kind of securities or other property purchasable
upon the exercise of this Option or the Exercise Price is adjusted, as herein provided, the Company shall give notice thereof to
the Participant, which notice shall state the number of Shares (and other securities or property) purchasable upon the exercise
of this Option and the Exercise Price of such Shares (and other securities or property) after such adjustment, setting forth a
brief statement of the facts requiring such adjustment and setting forth the computation by which such adjustment was made.

 

8.                 
Transfer Restrictions. Except as may otherwise be expressly permitted by the Board, the Option is not assignable
or transferable other than to a beneficiary designated to receive the Option upon the Participant’s death or by will or the
laws of descent and distribution, and the Option shall be exercisable during the lifetime of the Participant only by the Participant
(or, in the event of the Participant’s incapacity, the Participant’s legal representative or guardian). Any attempt
by the Participant or any other person claiming against, through or under the Participant to cause the Option or any part of it
to be transferred or assigned in any manner and for any purpose not permitted under this Agreement shall be null and void and without
effect ab initio.

 

 

 

 

    	 	7	 

     

    

 

9.                 
Rights as a Stockholder. No Shares shall be sold, issued or delivered pursuant to the exercise of the Option until
full payment for such Shares has been made or provided for (including, for this purpose, satisfaction of all applicable withholding
taxes). The Participant shall have no rights as a stockholder with respect to any Shares covered by the Option unless and until
the Option is exercised and the Shares purchased pursuant to such exercise are issued in the name of the Participant. Except as
otherwise specified, no adjustment shall be made for dividends or distributions of other rights for which the record date is prior
to the date such Shares are issued.

 

10.             
Tax Withholding. The Company’s obligation to issue Shares pursuant to the exercise of the Option shall be subject
to and conditioned upon the satisfaction by the Participant of applicable tax withholding obligations in accordance with Section
6 of this Agreement. If and to the extent the applicable withholding obligations is payable in cash, the Participant hereby authorizes
the Company to satisfy all or part of such tax withholding obligations by deductions from cash compensation or other payments that
would otherwise be owed to the Participant.

 

11.             
No Other Rights Conferred. Nothing contained herein shall be deemed to give the Participant a right to be retained
in the employ or other service of the Company or any affiliate or to affect the right of the Company and its affiliates to terminate,
or modify the terms and conditions of, the Participant’s employment or other service.

 

12.             
Successors. This Agreement shall be binding upon and shall inure to the benefit of the parties hereto and their respective
successors and permitted assigns.

 

13.             
Entire Agreement. This Agreement constitutes the entire agreement between the parties with respect to the subject
matter hereof and may not be modified except by written instrument executed by the parties.

 

14.             
Governing Law. This Agreement shall be governed by the laws of the State of Nevada, without regard to its principles
of conflict of laws.

 

15.             
Counterparts; Electronic Execution. This Agreement may be executed in separate counterparts, each of which will be
an original and all of which taken together shall constitute one and the same agreement. Signatures delivered by facsimile or electronic
mail, including by PDF, shall be effective as original signatures for all purposes.

 

The undersigned have
executed this Agreement as of the first date set forth above.

 

	 	PharmaCyte Biotech, Inc.
	 	 	 
	 	By: 	 
	 	Name: Kenneth L. Waggoner
	 	Title: Chief Executive Officer
	 	 	 
	 	 	 
	 	Participant
	 	 	 
	 	By:	 
	 	Name: Carlos A. Trujillo

 

 

 

 

 

 

 

    	 	8

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