Document:

EX-10.1

 Exhibit 10.1 

AMENDED AND RESTATED EMPLOYMENT AGREEMENT 

This AMENDED AND RESTATED EMPLOYMENT AGREEMENT (this “Agreement”), is made and entered into as of May 23, 2016
(the “Effective Date”), by and between Jeffrey P. McMullen (the “Executive”) and inVentiv Health, Inc., a Delaware corporation (the “Company”). 

WHEREAS, in its business, the Company has acquired and developed certain trade secrets, including, but not limited to,
proprietary processes, sales methods and techniques, and other confidential business and technical information, including, but not limited to, technical information, design systems, proprietary assays, pricing methods, pricing rates or discounts,
processes, procedures, formulas, design of computer software or improvement of any portion or phase thereof, whether patented or not, that is of any value whatsoever to the Company, as well as certain unpatented information relating to the
Company’s Business (as defined below), information concerning proposed new services, market feasibility studies, proposed or existing marketing techniques or plans (whether developed or produced by the Company or by any other entity for the
Company), other Proprietary Information (as defined below) and information about the Company’s employees, officers, and directors, which necessarily will be communicated to the Executive by reason of his employment with the Company; 

WHEREAS, the Company has strong and legitimate business interests in preserving and protecting its trade secrets and Proprietary
Information, and its substantial relationships with suppliers and clients, actual and prospective; 
 WHEREAS, the Company
desires to preserve and protect its legitimate business interests further by restricting competitive activities of the Executive during the term of employment and following (for a reasonable time) termination of employment; 

WHEREAS, the Executive and the Company are currently parties to that certain Amended and Restated Employment Agreement, dated as
of May 23, 2014 (the “Previous Employment Agreement”), and desire to amend and restate the Previous Employment Agreement to, among other things, extend the term of the agreement by two years; 

WHEREAS, the Company desires to continue to employ the Executive and to ensure the availability to the Company of the
Executive’s services, and the Executive is willing to accept such employment and render such services, all upon and subject to the terms and conditions contained in this Agreement; and 

WHEREAS, the Executive acknowledges and agrees that the payments, benefits, promises and undertakings performed, and to be
performed, as set forth herein exceed and are greater than the payments, benefits, promises and undertakings to which Executive would have been entitled had Executive not executed this Agreement. 

 NOW, THEREFORE, in consideration of the premises and the mutual covenants set forth
in this Agreement, and intending to be legally bound, the Company and the Executive agree as follows: 
 1. Representations and
Warranties. The Executive hereby represents and warrants to the Company that he (a) is not subject to any written non-solicitation or non-competition agreement affecting his employment with the Company (other than the Previous
Employment Agreement), (b) is not subject to any written confidentiality or nonuse/nondisclosure agreement affecting his employment with the Company (other than the Previous Employment Agreement), and (c) has not brought to the Company any
trade secrets, confidential business information, documents, or other personal property of a prior employer. 
 2. Term of
Employment. 
 (a) Term. Subject to Section 6 hereof, the Company hereby employs the Executive, and the Executive hereby
accepts employment with the Company, for a period commencing on the Effective Date and ending on the second (2nd) anniversary of the Effective Date (the “Employment Term”).
The period of time from the Effective Date until the first anniversary of the Effective Date shall be known as the “First Year.” The period of time from the end of the First Year until the second anniversary of the Effective Date shall be
known as the “Second Year.” 
 (b) Continuing Effect. Notwithstanding any termination of employment, at the end of the
Employment Term or otherwise, the provisions of Sections 7, 8, 9 and 11 hereof shall remain in full force and effect and the provisions of Sections 8 and 11 hereof shall be binding upon the legal representatives, successors and assigns of the
Executive. 
 3. Duties. 

(a) General Duties. The Executive shall serve as a Vice Chairman of the Company and shall perform the duties and responsibilities that
the Company’s Chief Executive Officer (“CEO”) may require of him and are customary for such position. The Executive shall use his best efforts to perform his duties and discharge his responsibilities pursuant to this Agreement
competently, carefully and faithfully. 
 (b) Devotion of Time. The Executive shall devote the amount of time and attention to the
business and affairs of the Company that are reasonably necessary to competently perform his duties. The Executive shall not enter the employ of or serve as a consultant to, or in any way perform any services with or without compensation to, any
other person, business or organization without the prior written consent of the CEO. Notwithstanding the foregoing, the Executive shall be permitted, subject to the first sentence of this Section 3(b) and Sections 7, 8, 9 and 10 hereof, to
(i) serve on corporate, advisory, civic or charitable boards or committees, including without limitation, the Syracuse University Biology Advisory Board, and service on the boards of directors of each of BioClinica, Patheon, and the Association
of Clinical Research Organizations, (ii) deliver lectures, fulfill speaking engagements or teach at educational institutions and (iii) manage personal investments. 

(c) Location of Office. The Executive’s principal business office shall be at the Company’s office location in Princeton, New
Jersey; provided, however, that the Executive’s job responsibilities shall include all business travel necessary to such requirements. 

(d) Adherence to Inside Information Policies. The Executive shall promptly execute any agreements requiring the Executive to abide by
any inside information policies either currently in effect or that may be put into effect during the Employment Term. 

  
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 (e) Board Service. The Company agrees to use its reasonable best efforts to cause
Executive to be re-elected to the Boards (the “Boards”) of Directors of the Company, inVentiv Group Holdings, Inc., inVentiv Midco Holdings, Inc. and inVentiv Holdings, Inc. Upon termination of Executive’s employment, Executive shall
resign from the Boards and cooperate with the Company to execute all documentation reasonably necessary to effect such resignation. During the Second Year, the Company will recommend to the Boards that Executive be awarded equity compensation
similar to independent Directors of the Company who may also be awarded such equity compensation. 
 4. Compensation and Expenses.

 (a) Annual Base Salary. For the services of the Executive to be rendered under this Agreement, during the Employment Term the
Company shall pay the Executive an annual base salary equivalent to $300,500 per annum during the First Year and $150,000 per annum during the Second Year (the “Annual Base Salary”). The Annual Base Salary shall be payable in
accordance with the Company’s normal payroll practices. In the Second Year the Company may, at its option, transition the Executive to a non-employee consultant at the same rate of compensation that would otherwise apply during the Second Year.

 (b) Perquisites. The Executive shall be entitled to administrative support substantially similar to the administrative support the
Executive receives as of the date hereof. In addition, during the First Year, the Executive shall be entitled to perquisites which shall have a cost to the Company of not more than $30,000. Benefits generally available to all other employees of the
Company shall not be deemed perquisites for purposes of this Section 4(b). 
 (c) Conditions to Reimbursement. Any reimbursement
provided to the Executive with respect to the perquisites set forth in Section 4(b) shall be subject to the following terms and conditions: (i) the Executive must submit all required receipts and documentation for each such reimbursable
expense and (ii) the Company shall provide the Executive with the requisite reimbursement within thirty (30) business days thereafter. In addition, any amounts to which the Executive becomes entitled pursuant to this Section 4
(whether by way of reimbursement or in-kind benefits) in each calendar year within the Employment Term or any other reimbursement to which the Executive becomes entitled pursuant to the provisions of this Agreement during such calendar year shall
not reduce the amounts (or in-kind benefits) to which the Executive may become entitled hereunder in any other calendar year within the Employment Term. In no event, however, will any expense be reimbursed after the close of the calendar year
following the calendar year in which that expense was incurred. None of the Executive’s rights to reimbursement or in-kind benefits hereunder may be liquidated or exchanged for any other benefit. 

(d) Annual Review of Salary. The Executive will have an annual performance and salary review by the CEO in accordance with the
Company’s normal practices. Pursuant to this annual review, the Company shall not reduce the Executive’s Annual Base Salary below the then current Annual Base Salary. 

(e) Annual (Cash) Incentive. In addition to any other compensation received pursuant to this Agreement, subject to the Executive’s
continued employment at the end of each calendar year within the Employment Term, the Executive shall be eligible to receive an annual cash bonus based on achievement of financial and other objectives established annually by the CEO. 

  
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 (f) Expenses. In addition to any compensation received pursuant to this Section 4,
the Company shall reimburse or advance funds to the Executive for reasonable travel, entertainment, professional dues and miscellaneous expenses incurred in connection with the performance of his duties under this Agreement and in accordance with
the Company’s policies relating to travel and expenses, subject to receipt by the Company of evidence of such expenses. The Executive must submit all required receipts and documentation for each such reimbursable expense within sixty
(60) days following the last day of the month of the incurrence of that expense. 
 5. Benefits. 

(a) Vacation. Executive shall be entitled to take as much vacation time as he deems appropriate for his role so long as he is meeting
the expectations of the CEO. In light of this policy, Executive shall not accrue vacation time. 
 (b) Employee Benefit Programs. The
Executive shall be entitled to participate in any pension, 401(k), medical insurance, disability insurance, life insurance or other employee benefit plan that is maintained by the Company, including reimbursement of membership fees in professional
organizations, subject to the eligibility requirements of these specific plans. In the event the Company chooses to transition Executive to a consultant as set forth in section 4(a) of this Agreement, then the Executive shall no longer be entitled
to employee benefits; provided, however, if thereafter the Executive purchases continuation health coverage through COBRA, then the Company shall reimburse the Executive the cost of the applicable premium until the end of the Second Year. 

(c) Death Benefit. In the event of the Executive’s death prior to the end of the Employment Term, the Executive’s estate or
his designated beneficiary shall be entitled to receive the Executive’s Annual Base Salary, plus any earned bonuses, for the balance of the Employment Term, with such balance to be paid in a series of successive equal installments over that
period in accordance with the Company’s normal payroll practices for salaried employees, with the first such installment to be paid within sixty (60) days after the date of his death. 

6. Termination; Severance. 

(a) Certain Definitions. For purposes of this Agreement: 

“Cause” means that the Executive has: (i) materially failed to meet the Company’s expectations with respect to the
Executive’s job performance set forth in Section 3 of this Agreement; (ii) been convicted of, or pleaded guilty or no contest to, a felony involving any subject matter; (iii) been charged by a government agency with a felony
relating to the business of the Company or any of its Affiliated Companies; (iv) been convicted of, or pleaded guilty or no contest to, a misdemeanor directly involving the Executive’s employment that directly affects the business of the
Company; (v) been found after an internal investigation to have engaged in sexual misconduct, inappropriate sexual conduct with an employee or consultant of the Company, sexual harassment or other unlawful discrimination and/or harassment,
which is related to the Executive’s employment or the business of the Company and/or otherwise violated the Company’s sexual harassment policy, anti-fraternization policy and/or anti-discrimination policies; (vi) failed to carry out
the duties and responsibilities assigned to the Executive which are consistent with the terms of this Agreement; (vii) misappropriated the Company’s funds or otherwise defrauded the Company; (viii) breached his fiduciary duty to the
Company resulting in profit to him, directly or indirectly; (ix) been convicted of illegal possession or illegal use of a controlled substance; (x) engaged in chronic alcohol abuse or the use of

  
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illegal drugs, chemicals or controlled substances or the abuse of otherwise legal drugs or chemicals or controlled substances that affects the performance of his duties as reasonably determined
by the Company; (xi) failed or refused to cooperate in any official investigation conducted by or on behalf of the Company; (xii) breached any material provision of this Agreement, after notice and a reasonable opportunity to cure such
behavior (if the behavior is of a nature that can be cured); intentionally or willfully failed to comply with the reasonable directives of the Board; committed an act or omission constituting gross negligence or willful misconduct which causes, at
least in part, the Company to restate its financial statements for a completed fiscal period after having finalized such financial statements; or (xv) been found by a court or any federal or state governmental authority, in a final
determination, to have violated any applicable securities laws, whether such finding was after a hearing or trial or on consent without admitting or denying any allegations of wrongdoing. 

“Disability” means the occurrence of either of the following circumstances: (i) if the Executive is deemed disabled for
purposes of any long-term disability insurance policy paid for by the Company and in effect at such time, or (ii) if in the exercise of the reasonable judgment of the Company, due to accident, mental or physical illness, or any other reason,
the Executive has become physically or mentally incapable of performing, with or without reasonable accommodation, the essential functions of his employment for a period of more than one hundred twenty (120) consecutive days or for one hundred
eighty (180) days within a three hundred and sixty-five (365) day period. 
 “Employment Termination Date” with
respect to any purported termination of the Executive’s employment, shall mean (i) if the Executive’s employment is terminated by his death, the date of his death, (ii) if the Executive’s employment is terminated for Cause
or without Cause, the date specified in the Notice of Termination, (iii) if the Executive’s employment is terminated as a result of a Disability, the date on which it is finally determined that the Executive is Disabled and (iv) if
the Executive terminates his employment for Good Reason or otherwise voluntarily terminates his employment, the date specified in the Notice of Termination, which shall be no later than the last day the Executive performs his duties. In the event
that the termination of the Executive’s employment does not constitute a “separation from service” as defined in Section 409A of the Internal Revenue Code of 1986, including all regulations and other guidance issued pursuant
thereto (the “Code”), the Executive’s rights to the payments and benefits described in Section 6 shall vest upon the Employment Termination Date, but no payment to the Executive that is subject to Code Section 409A shall be
paid until the Executive incurs a separation from service (subject to Section 6(f)), and any amounts that would otherwise have been paid prior to such date shall be paid instead as soon as practicable after such date. 

“Good Reason” means (i) the material breach of any of the material terms or conditions of this Agreement by the
Company, which is not cured or otherwise remedied by the Company within thirty (30) business days after receiving written notice from the Executive or (ii) the Executive, with or without a change in title or formal corporate action, no
longer exercises substantially all of the duties and responsibilities of the Vice Chairman of the Company, other than in connection with a voluntary resignation by the Executive as Vice Chairman of the Company; provided, however, that the
Executive must resign within one hundred eighty (180) days of the initial occurence of the foregoing circumstance and must deliver a Notice of Termination to the Company stating the facts and circumstances he alleges constitute Good Reason
within ninety (90) days of the first occurence of such fact or circumstance or the Executive shall be deemed to have waived the Executive’s right to terminate for Good Reason with respect to any such facts or circumstances; and
provided, further, that “Good Reason” shall not exist as a result of a termination for Cause in accordance with Section 6(b)(ii) of this Agreement. For the avoidance of doubt, the appointment of a President, Chief Executive
Officer or other similar officer of the Company’s Clinical segment shall not constitute Good Reason. 

  
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 “Notice of Termination” means a notice delivered by one party hereto to the
other party hereto, which notice (i) if delivered by the Company to the Executive, shall indicate the specific termination provision in this Agreement relied upon and set forth in reasonable detail the facts and circumstances claimed by the
Company to provide a basis for termination of the Executive’s employment with the Company under the provision so indicated, or (ii) if delivered by the Executive to the Company, shall, if applicable, set forth in reasonable detail the
facts and circumstances claimed by the Executive to provide a basis for termination by the Executive for Good Reason. 

“Person” shall have the meaning ascribed thereto in Section 3(a)(9) of the Securities Exchange Act of 1934, as amended,
as modified, applied and used in Sections 13(d) and 14(d) thereof; provided, however, a Person shall not include (i) the Company, (ii) a trustee or other fiduciary holding securities under an employee benefit plan of the Company (in
its capacity as such), (iii) an underwriter temporarily holding securities pursuant to an offering of such securities, or (iv) a corporate entity owned, directly or indirectly, by the Company’s stockholders in substantially the same
character and proportions as their ownership of interests in the Company. 
 (b) Termination. 

(i) Either the Company or the Executive, in its or his sole discretion, may terminate the Executive’s employment without Cause or Good
Reason, as applicable, at any time upon thirty (30) days written notice. Upon the Employment Termination Date, whether with or without Cause or Good Reason, the Executive shall have no right to compensation or reimbursement under Section 4
(except for compensation earned or reimbursable expenses incurred through the Employment Termination Date) or to participate in any employee benefit programs under Section 5 for any period subsequent to the Employment Termination Date, except
as provided for by law or this Agreement. In the event that the Executive is involuntarily terminated for any reason other than for Cause or the Executive terminates his employment for Good Reason, he shall be eligible to receive a bonus payment,
pro-rated for the time worked, according to the bonus terms, to be paid at the customary bonus payment time in accordance with normal payroll practices. On or before the Employment Termination Date or prior to receiving (and as a condition to
receiving) any final compensation or expenses due him, the Executive shall (a) return to the Company’s headquarters or the offices of the Company in Princeton, New Jersey, as the Company may request, (b) participate in an exit
interview, as the Company may request, and (c) upon presentation by the Company, execute a “Certificate of Conclusion of Employment,” certifying that he has complied with his obligations and acknowledging his continuing obligations
under this Agreement. The Executive’s failure to comply with the requirements of this Section shall constitute a material breach of this Agreement. 

(ii) The Company may terminate the Executive’s employment pursuant to the terms of this Agreement at any time for Cause (as defined
above) by giving Notice of Termination. The Executive shall have ten (10) days from the date of such Notice of Termination to provide the Company with evidence that the Company is mistaken as to Cause and that the Executive’s conduct does
not meet the criteria for termination for Cause. During such ten (10) day period, the Executive shall be suspended without pay and shall no longer perform any of the duties of his position; provided, however, that if his employment is
reinstated, then the Executive shall be paid for such ten (10) day period or if the termination is upheld, the effective Employment Termination Date shall be deemed to be the date specified in the Notice of Termination. Upon any such
termination for Cause, the Executive shall have no right to compensation or reimbursement under Section 4 (except for compensation and bonuses earned or reimbursable expenses incurred through the Employment Termination Date), or to participate
in any employee benefit programs under Section 5 for any period subsequent to the Employment Termination Date, except as provided by law. 

  
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 (ii) To the extent the Executive is, on the Employment Termination Date, participating in one or
more deferred compensation arrangements subject to Section 409A of the Code, the payments and benefits provided under those arrangements shall continue to be governed by, and to become due and payable in accordance with, the specific terms and
conditions of those arrangements, and nothing in this Agreement shall be deemed to modify or alter those terms and conditions. 
 (d)
Benefit Limit. 
 (i) In the event that any payments or benefits to which the Executive becomes entitled in accordance with the
provisions of this Agreement (or any other agreement with the Company or other affiliated company) (the “Total Payments”) would otherwise constitute a parachute payment under Code Section 280G(b)(2), then such payments and/or
benefits will be subject to reduction to the extent necessary to assure that the Executive receives only the greater of (i) the amount of those payments which would not constitute such a parachute payment or (ii) the amount which
yields Executive the greatest after-tax amount of benefits after taking into account any excise tax imposed under Code Section 4999 (“Excise Tax”) on the payments and benefits provided to the Executive under this Agreement (or
on any other payments or benefits to which the Executive may become entitled in connection with any change in control or ownership of the Company or the subsequent termination of his employment with the Company). 

(ii) In the event that a reduction in benefits is required to satisfy the benefit limit of this subparagraph (d), such reduction shall be
calculated only to the extent that the after-tax value to the Executive of such reduced benefits would exceed the after-tax value to the Executive of the total benefits to be received by the Executive without application of such reduction;
provided, that such reduction shall occur in the following order: (1) cash payments subject to Section 409A of the Code; (2) cash payments not subject to Section 409A of the Code; and (3) non-cash forms of benefits; and
provided, further, that to the extent any payment to be reduced pursuant to this sentence is to be made over time (e.g., in installments, etc.), then such payments shall be reduced in reverse chronological order. 

(iii) For purposes of determining whether and the extent to which the Total Payments will be subject to reduction, (A) no portion of the
Total Payments the receipt or enjoyment of which the Executive shall have effectively waived in writing shall be taken into account, (B) no portion of the Total Payments shall be taken into account which in the good faith opinion of the Company
does not constitute a “parachute payment” within the meaning of Section 2800(b)(2) of the Code (including by reason of Section 280G(b)(4)(A) of the Code), and in calculating Excise Tax, no portion of such Total Payments shall be
taken into account which constitutes reasonable compensation for services actually rendered, within the meaning of Section 280G(b)(4)(B) of the Code, in excess of the “base amount” (as defined in Section 280G(b)(3) of the Code)
allocable to such reasonable compensation, and (C) the value of any noncash benefit or any deferred payment or benefit included in the Total Payments shall be determined in good faith by the Company in accordance with the principles of Sections
280G(d)(3) and (4) of the Code. For purposes of this Section 6(d)(iii), the Executive shall be deemed to pay federal income taxes at the highest marginal rate of federal income taxation in the calendar year in which the applicable payment
is to be made and state and local income taxes at the highest marginal rate of taxation in the state and locality of the Executive’s residence in the calendar year in which the applicable payment is to be made, net of the maximum reduction in
federal income taxes that could be obtained from deduction of such state and local taxes. 

  
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 (e) Conditions on Payment. At the time that payments are made under this Section, the
Company shall provide the Executive with a detailed written statement setting forth the manner in which such payments were calculated and the basis for such calculations. Notwithstanding the foregoing, all Severance Payments shall immediately cease
and no longer be payable if Executive violates any of the terms set forth in Sections 7 or 8 hereof. Such remedy shall be in addition to any and all other remedies available by law or equity. 

(f) Delayed Commencement Date. Notwithstanding any provision to the contrary in this Agreement, no payment or benefit to which the
Executive otherwise becomes entitled under this Section 6 shall be made, paid or provided prior to the earlier of (i) the expiration of the six (6) month period measured from the date of the Executive’s “separation
from service” with the Company (as such term is defined in Treasury Regulations issued under Code Section 409A) or (ii) the date of the Executive’s death, if the Executive is deemed at the time of such separation from service to
be a “key employee” within the meaning of that term under Code Section 416(i) and such delayed commencement is otherwise required in order to avoid a prohibited distribution under Code Section 409A(a)(2). Upon the expiration of
the applicable Code Section 409A(a)(2) deferral period, all payments and benefits deferred pursuant to this subparagraph (f), whether they would have otherwise been payable in a single sum or in installments in the absence of such deferral,
shall be paid or reimbursed to the Executive in a lump sum, and any remaining payments and benefits due under this Section 6 shall be paid or provided in accordance with the normal payment dates specified for them herein. 

(g) Notice of Termination. Any purported termination of the Executive’s employment with the Company (other than by reason of
death) shall be communicated by written Notice of Termination from one party hereto to the other party hereto in accordance with Section 14. 

7. Restriction on Activities of the Executive. 

(a) Non-Competition Restrictions. During the Employment Term and for twelve (12) months after the Employment Termination Date (the
“Restricted Period”), whether such termination is pursuant to this Agreement or otherwise, Executive shall not, directly or indirectly, either alone or in conjunction with any person, firm, association, company, corporation or other
entity, anywhere within the Territory (as defined below), own, manage, operate, or participate in the ownership, management, operation, or control of, or be employed by or provide services to, any person, business or entity which competes with the
Company’s Business (as defined below) where the Executive would have responsibilities that are entirely or substantially similar to the responsibilities the Executive had at any time during the last twenty-four (24) months of the
Executive’s employment with the Company or in which the Executive would have responsibility for or access to confidential information that is similar to or relevant to that Proprietary Information which the Executive had access to during the
last twenty-four (24) months of the Executive’s employment with the Company. Notwithstanding anything to the contrary, nothing in this Section 7(a) prohibits the Executive from being a passive owner of not more than five percent
(5%) of the outstanding stock of any class of a corporation which is publicly traded, so long as the Executive has no active participation in the business of such corporation. For purposes of this Agreement, the “Company’s
Business” shall mean the business of designing, developing, marketing, selling and/or providing for (i) 

  
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pharmaceutical, life sciences, medical device and medical diagnostic companies: (A) the commercialization of pharmaceuticals, biologics and medical devices or diagnostic products which
includes the sales, marketing, naming, advertising and assessing of patient outcomes for the Company’s and Affiliated Companies’ clients, (B) clinical research organizations, (C) staffing clinical trial and/or clinical research
and development personnel, and (D) consulting services which includes the brand management, business development, clinical development, medical affairs, pricing and market access and sales for the Company’s and Affiliated Companies’
clients, (ii) health care providers, third-party administrators and insurers: medical claims review and negotiations and (iii) any other business that the Company and/or an Affiliated Company engages in, or which the Company and/or an
Affiliated Company has developed definitive plans to engage in, as of Executive’s Termination Date. For purposes of this Agreement, the “Territory” shall mean every State or foreign country where the Company and/or an Affiliated
Company maintains employees, owns or leases property or otherwise conducts business during the Restricted Period. “Affiliated Company” means any company, directly or indirectly, controlled by, controlling or under common control with
inVentiv Group Holdings, Inc. 
 (b) Non-Solicitation and No-Hire Restrictions. During the Restricted Period, whether such
termination is pursuant to this Agreement or otherwise, Executive shall not, directly or indirectly, either alone or in conjunction with any person, firm, association, company, corporation or other entity: (i) solicit, or attempt to solicit,
any officer, director, consultant or employee of the Company or an Affiliated Company to terminate or diminish such individual’s employment or engagement with the Company or such Affiliated Company, (ii) hire any officer, director,
consultant or employee of the Company or an Affiliated Company or (iii) solicit the sale of, or sell or offer, any products or services that are similar to or competitive with products or services sold by, offered by, manufactured by, designed
by, or distributed by the Company or an Affiliated Company, to any person, company or entity which was a customer or potential customer of the Company or an Affiliated Company for such products or services and with whom Executive had direct contact
or about whom Executive learned Proprietary Information at any time during the last twenty-four (24) months of Executive’s employment with the Company or an Affiliated Company. 

(c) Non-Disparagement Restrictions. Executive agrees that Executive shall not disparage the Company, an Affiliated Company, or any of
their products or practices, any of their respective directors, officers or employees, either orally or in writing, at any time. The Company will use reasonable efforts to instruct its senior officers and directors to not disparage Executive, either
orally or in writing, at any time. Nothing in this Section 7(c) shall limit the ability of the Executive, the Company and its senior officers or directors to provide truthful testimony as required by law or any judicial or administrative
process. 
 8. Non-Disclosure of Proprietary Information. 

(a) Proprietary Information. In the course of service to the Company or an Affiliated Company, the Executive will be provided, learn,
develop and have access to trade secrets, confidential information and proprietary materials regarding the organization, business and finances of the Company or an Affiliated Company which is not generally available to the public and which has been
developed or acquired, or will be developed or acquired, at 

  
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considerable effort and expense by the Company or an Affiliated Company. Such information shall hereinafter be called “Proprietary Information” and may include, but is not limited to,
(i) products, (ii) services, (iii) designs, (iv) methods, (v) techniques, (vi) systems, (vii) know-how, (viii) strategic or technical data, (ix) marketing research data, (x) product research and
development data, (xi) sales techniques, (xii) sales data, (xiii) confidential customer lists, (xiv) software, (xv) business plans, (xvi) pricing information, (xvii) employee personnel files, (xviii) clinical,
prescriber, pharmacy and/or patient data, (xix) recruiting information, including, but not limited to, candidate data and client preference and contact data, and (xx) any other information gained in the course of the Executive’s
employment with the Company or an Affiliated Company that could reasonably be expected to be deleterious to the Company or an Affiliated Company if disclosed to third parties. Proprietary Information shall not be considered generally available to
the public if the Executive or others improperly reveal such information to the public without the Company’s or an Affiliated Company’s express written consent and/or in violation of an obligation of confidentiality to the Company or an
Affiliated Company. 
 (b) Legitimate Business Interests. The Executive recognizes that the Company has legitimate business interests
to protect and, as a consequence, the Executive agrees to the restrictions contained in this Agreement because they further the Company’s legitimate business interests. These legitimate business interests include, but are not limited to
(i) trade secrets, (ii) valuable confidential business or professional information that otherwise does not qualify as trade secrets, including all Proprietary Information, (iii) substantial relationships with specific prospective or
existing Clients or clients, (iv) Client goodwill associated with the Company’s business and (v) specialized training relating to the Services and the Company’s technology, methods and procedures. The Executive agrees that the
foregoing covenants set forth in Sections 7, 8 and 11 are reasonable and necessary to protect the Company’s and Affiliated Company’s trade secrets and other Proprietary Information, good will, stable workforce, and customer relations. 

(c) Confidentiality. The Proprietary Information shall be held by the Executive in the strictest confidence and shall not, without the
prior written consent of the Company, be disclosed to any person other than in connection with the Executive’s employment with the Company. The Executive further acknowledges that such Proprietary Information as is acquired and used by the
Company is a special, valuable and unique asset. The Executive shall exercise all due and diligent precautions to protect the integrity of the Company’s Proprietary Information and to keep it confidential whether it is in written form, on
electronic media or oral. The Executive shall not copy any Proprietary Information except to the extent necessary to his employment nor remove any Proprietary Information or copies thereof from the Company’s premises except to the extent
necessary to his employment and then only with the authorization of an officer of the Company. All records, files, materials and other Proprietary Information obtained by the Executive in the course of his employment with the Company are
confidential and proprietary and shall remain the exclusive property of the Company or its Clients, as the case may be. The Executive shall not, except in connection with and as required by his performance of his duties under this Agreement, for any
reason use for his own benefit or the benefit of any person or entity with which he may be associated or disclose any such Proprietary Information to any person, firm, corporation, association or other entity for any reason or purpose whatsoever
without the prior written consent of the Company. 
 (d) References to the Company in this Section 8 shall include the Company’s
Affiliated Companies. 

  
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 9. Resolution of Disputes. 

(a) Injunctive Relief. Executive acknowledges and agrees that a breach by the Executive of any of the provisions of Sections 7, 8, 10
or 11 hereof will cause irreparable damage to the Company for which monetary damages alone will not constitute an adequate remedy. In the event of such breach or threatened breach, the Company shall be entitled as a matter of right (without
being required to prove damages or furnish any bond or other security) to obtain a restraining order, an injunction, an order of specific performance, or other equitable or extraordinary relief from any court of competent jurisdiction restraining
any further violation of such provisions by the Executive or requiring the Executive to perform the Executive’s obligations hereunder, and will additionally be entitled to an award of attorneys’ fees incurred in connection with securing
any relief hereunder. Such right to equitable or extraordinary relief shall not be exclusive but shall be in addition to all other rights and remedies to which the Company may be entitled at law or in equity, including, without limitation, the right
to recover monetary damages for the breach by the Executive of any of the provisions of this Agreement. 
 (b) Any action between the
Company and Executive must be commenced in Mercer County, New Jersey. The Executive and the Company irrevocably and unconditionally submit to the exclusive jurisdiction of such courts and agree to take any and all future action necessary to submit
to the jurisdiction of such courts. The Executive and the Company irrevocably waive any objection that they now have or hereafter irrevocably waive any objection that they now have or hereafter may have to the laying of venue of any suit, action or
proceeding brought in any such court and further irrevocably waive any claim that any such suit, action or proceeding brought in any such court has been brought in an inconvenient forum. Final judgment against the Executive or the Company in any
such suit shall be conclusive and may be enforced in other jurisdictions by suit on the judgment, a certified or true copy of which shall be conclusive evidence of the fact and the amount of any liability of the Executive or the Company therein
described, or by appropriate proceedings under any applicable treaty or otherwise. 
 10. Conflicts of Interest. Except as
otherwise set forth in Section 7(a), while employed by the Company, the Executive shall not, directly or indirectly, unless approved by the Company: 

(a) participate as an individual in any way in the benefits of transactions with any of the Company suppliers or clients, including, without
limitation, having a financial interest in the Company’s suppliers or clients, or making loans to, or receiving loans from, the Company’s suppliers or clients; 

(b) realize a personal gain or advantage from a transaction in which the Company has an interest or use information obtained in connection
with the Executive’s employment with the Company for the Executive’s personal advantage or gain; or 
 (c) accept any offer to
serve as an officer, director, partner, consultant, manager with, or to be employed in a technical capacity by, a person or entity that does business with the Company. 

As used in Section 10(a), (b) or (c), references to the Company also includes an Affiliated Company. 

11. Inventions, Ideas, Processes, and Designs. All inventions, ideas, processes, programs, software, and designs (including all
improvements) (a) conceived or made by the Executive during the course of his employment with the Company (whether or not actually conceived during 

  
 11 

 
regular business hours) and for a period of six (6) months subsequent to the Employment Termination Date or the expiration of the Employment Term and (b) related to the business of the
Company, shall be disclosed in writing promptly to the Company and shall be the sole and exclusive property of the Company. An invention, idea, process, program, software, or design (including an improvement) shall be deemed related to the business
of the Company if (x) it was made with the Company’s equipment, supplies, facilities, or Proprietary Information, (y) results from work performed by the Executive for the Company, or (z) pertains to the current business or
demonstrably anticipated research or development work of the Company. The Executive shall cooperate with the Company and its attorneys in the preparation of patent and copyright applications for such developments and, upon request, shall promptly
assign all such inventions, ideas, processes, and designs to the Company. The decision to file for patent or copyright protection or to maintain such development as a trade secret shall be in the sole discretion of the Company, and the Executive
shall be bound by such decision. References to the Company in this Section 11 shall include the Company’s Affiliated Companies. 

12. Assignability. The rights and obligations of the Company under this Agreement shall inure to the benefit of and be binding
upon the successors and assigns of the Company. The Executive’s obligations hereunder may not be assigned or alienated and any attempt to do so by the Executive will be void. 

13. Severability. 

(a) The Executive expressly agrees that the character, duration and geographical scope of the non-competition provisions set forth in this
Agreement are reasonable in light of the circumstances as they exist on the date hereof. Should a decision, however, be made at a later date by a court of competent jurisdiction that the character, duration or geographical scope of such provisions
is unreasonable, then it is the intention and the agreement of the Executive and the Company that this Agreement shall be construed by the court in such a manner as to impose only those restrictions on the Executive’s conduct that are
reasonable in the light of the circumstances and as are necessary to assure to the Company the benefits of this Agreement. If, in any judicial proceeding, a court shall refuse to enforce all of the separate covenants deemed included herein because
taken together they are more extensive than necessary to assure to the Company the intended benefits of this Agreement, it is expressly understood and agreed by the parties hereto that the provisions of this Agreement that, if eliminated, would
permit the remaining separate provisions to be enforced in such proceeding shall be deemed eliminated, for the purposes of such proceeding, from this Agreement. 

(b) If any provision of this Agreement otherwise is deemed to be invalid or unenforceable or is prohibited by the laws of the state or
jurisdiction where it is to be performed, this Agreement shall be considered divisible as to such provision and such provision shall be inoperative in such state or jurisdiction and shall not be part of the consideration moving from either of the
parties to the other. The remaining provisions of this Agreement shall be valid and binding and of like effect as though such provisions were not included and the invalid or unenforceable provision shall be substituted with a provision which most
closely approximates the intent and the economic effect of the invalid or unenforceable provision and which would be enforceable to the maximum extent permitted in such jurisdiction or in such case. 

  
 12 

 14. Notices and Addresses. All notices, offers, acceptance and any other acts under
this Agreement (except payment) shall be in writing, and shall be sufficiently given if delivered to the addressee in person, by Federal Express or similar overnight delivery, or by facsimile delivery followed by Federal Express or similar next
business day delivery, as follows: 
  

	 	(i)	if to the Company: 

 inVentiv Health, Inc. 

One Van de Graaff Drive 

Burlington, MA 01803 
 Attn:
General Counsel 
  

	 	(ii)	if to the Executive: 

 At the most recent address on file at the Company or to such other
address as the party to whom notice is given may have previously furnished to the other in writing in the manner set forth above. 
 15.
Counterparts. This Agreement may be executed in one or more counterparts, each of which shall be deemed an original but all of which together shall constitute one and the same instrument. The execution of this Agreement may be by
actual or facsimile signature. 
 16. Attorneys’ Fees. In the event that there is any controversy or claim arising out of
or relating to this Agreement, or to the interpretation, breach or enforcement thereof, and any action or proceeding is commenced to enforce the provisions of this Agreement, each party shall be responsible for its own attorneys’ fee, costs and
expenses. 
 17. Governing Law. This Agreement and any dispute, disagreement, or issue of construction or interpretation
arising hereunder whether relating to its execution, its validity, the obligations provided therein or performance shall be governed or interpreted according to the internal laws of the State of New Jersey without regard to choice of law
considerations. 
 18. Entire Agreement. This Agreement constitutes the entire agreement between the parties and supersedes
all prior oral and written agreements between the parties hereto with respect to the subject matter hereof, including, but not limited to, the Previous Employment Agreement, which is terminated and no longer in force and effect. Neither this
Agreement nor any provision hereof may be changed, waived, discharged or terminated orally, except by a statement in writing signed by the party or parties against which, enforcement or the change, waiver discharge or termination is sought. The
Company and the Executive hereby agree that as of the Effective Date, the terms and conditions of the Previous Employment Agreement are terminated and no longer of force or effect. 

19. Additional Documents. The parties hereto shall execute such additional instruments as may be reasonably required by their
counsel in order to carry out the purpose and intent of this Agreement and to fulfill the obligations of the parties hereunder. 
 20.
Section and Paragraph Headings. The section and paragraph headings in this Agreement are for reference purposes only and shall not affect the meaning or interpretation of this Agreement. 

  
 13 

 IN WITNESS WHEREOF, the Company and the Executive have executed this Agreement effective as of the date set forth
above. 
  

									
	inVentiv Health, Inc.	 		 		 	Executive
					
	By:	 	 /s/ Eric R. Green
	 		 		 	 /s/ Jeffrey P. McMullen

	Name:	 	Eric R. Green	 		 		 	Jeffrey P. McMullen
	Title:	 	General Counsel	 		 		 	

  
 14EX-10.2

 Exhibit 10.2 

inVentiv Group Holdings, Inc. 

May 23, 2016 
 David Southwell 

20 Monadnock Rd. 
 Chestnut Hill, MA 02467 

 

	 	Re:	Appointment to Board of Directors 

 Dear Mr. Southwell: 

Further to your appointment to the boards of directors (the “Boards”) of inVentiv Group Holdings, Inc., inVentiv Midco
Holdings, Inc., inVentiv Holdings, Inc. and inVentiv Health, Inc. (collectively, the “Companies”) as of May 23, 2016, this letter agreement, together with Annex A hereto, sets forth the proposed compensation
arrangements for your service as a member of the Boards and their committees. 
 This letter agreement (together with all related incentive
plan award agreements) constitutes the entire agreement between you and the Companies in respect of the subject matter contained herein and supersedes all prior agreements, understandings and arrangements, whether oral or written, by any
representative of any party hereto in respect of such subject matter. 
 This letter agreement may not be amended or waived except by an
instrument in writing signed by each of the parties to this letter agreement. This letter agreement will be governed by, and construed in accordance with, the internal laws of the State of New York without giving effect to any choice of law
principles that would require or permit the application of laws of another jurisdiction. This letter agreement may be executed in any number of counterparts, each of which will be an original, and all of which, when taken together, will constitute
one and the same instrument. Delivery of an executed signature page of this letter agreement by facsimile transmission will be effective as delivery of a manually executed counterpart hereof. 

[Signature Page Follows] 

 Please confirm that the foregoing is our mutual understanding by signing and returning to the
Companies an executed counterpart of this letter agreement. 
 Very truly yours, 

 

			
	
		
	By:	 	/s/ Eric R. Green
		 	Name: Eric R. Green
		 	Title: General Counsel and Secretary

 Accepted and agreed to as of 

the date first written above by: 
  

			
	
		
		 	/s/ David Southwell
		 	David Southwell

 Signature Page to Director Letter Agreement 

 Terms of Service 
  

	 Scope 
	● Subject to the “Term of Service” paragraph below, you will serve as: 

  

	 	● Director of the Companies 

  

	 	● Chairman of the Audit Committee 

  

	 	● You may also be asked to serve as a member of other committees of the boards of directors of the Companies. 

  

	 	● You will be expected to attend or participate in all regular and special meetings of the Companies’ board of directors and any committees on which you serve. 

 

	 Fees & Expenses 
	● You will be reimbursed for reasonable and documented out-of-pocket expenses you incur in connection with serving as a director or a member of any committee of the boards of directors of the Companies, including documented travel
expenses incurred to attend meetings incident to your duties and in accordance with the standard practices of the Companies, as in effect from time to time. 

  

	 	● As compensation for serving as a director of the Companies, for as long as you serve in that capacity, you will receive an annual fee of $75,000 that will be payable in equal quarterly installments on the first
business day of each calendar quarter; provided, however, that as long as you serve as Chairman of the Audit Committee, your annual free shall be increased by $20,000 to a total of $95,000. 

 

	 Equity Compensation 
	● As additional consideration for your service as a director of the Companies, you will receive an initial commitment for the Company to award you a $200,000 stock option award with the number of options calculated as follows:
$200,000 / FMV of a share of stock on the option grant date. The stock options will be granted pursuant and subject to the inVentiv Group Holdings, Inc. 2010 Equity Incentive Plan (as amended, the “Plan”), and we expect the option
will have a one year vesting horizon. You will be eligible to participate in future Directors’ compensation programs as the Board of Directors may approve. 

  

	 D&O Indemnity & Insurance 
	● The Companies’ organizational documents (articles, charters, by-laws, etc.) will provide you with a customary indemnity to protect you against claims from third parties resulting from your service as a director and the
Companies will provide and maintain directors’ and officers’ liability insurance coverage for you in respect of the period for which you are a director of the Companies at such levels, for such risks and subject to such terms, as the
Companies provide and maintains such cover for its directors generally. 

	 Term of Service 
	● All service in on an annual basis, subject to your removal, non-reelection or non-reappointment in accordance with applicable law and the organizational documents of the Companies or your earlier death, permanent disability or
resignation. 

  

	 	● Should you resign as a director or committee member, the Company may, at its sole option, deem such resignation as applicable to every such position you then hold even if your resignation is to less than all of
your positions. Any resignation must be in writing. 

  

	 Withholding 
	● To the extent applicable, all payments hereunder will be subject to any required withholding of Federal, state and local taxes pursuant to any applicable law or regulation. 

* * *

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