Document:

AMENDMENT NO. 5 TO CREDIT AGREEMENT
                       -----------------------------------

     AMENDMENT NO. 5 TO AMENDED AND RESTATED CREDIT AGREEMENT (this "Amendment")
is effective as of November 30, 2002, by and among HAUSER, INC., a Delaware
corporation (the "Company"), HAUSER TECHNICAL SERVICES, INC., a Delaware
corporation, BOTANICALS INTERNATIONAL EXTRACTS, INC., a Delaware corporation,
and ZETAPHARM, INC., a New York corporation, (collectively, the "Borrowers"),
and WELLS FARGO BANK, N.A. (the "Lender").

                                    RECITALS
                                    --------

     WHEREAS, the Borrowers are currently indebted to the Lender pursuant to the
terms and conditions of that certain Amended and Restated Credit Agreement dated
as of December 7, 2001 (the "Current Agreement"; as amended hereby and from time
to time, the "Agreement"); and

     WHEREAS, the Lender and the Borrowers have agreed to certain changes in the
terms and conditions set forth in the Current Agreement and have agreed to amend
the Current Agreement to reflect said changes.

     NOW, THEREFORE, for valuable consideration, the receipt and sufficiency of
which are hereby acknowledged, the parties hereto agree that the Current
Agreement shall be amended as follows:

A. Amendments.
   ----------

     1. In Section 1.01 of the Current Agreement, the defined term "Commitment"
is amended by replacing the dollar amount "$9,000,000" with the dollar amount
"$8,700,000".

     2. In Section 1.01 of the Current Agreement, the defined term "Revolving
Credit Commitment" is amended by replacing the dollar amount "$9,000,000" with
the dollar amount "$8,700,000".

     3. In Section 1.01 of the Current Agreement, the defined term "Revolving
Credit Facility Availability Period" is amended by replacing the phrase
"November 30, 2002" with the phrase "December 31, 2002".

     4. In Section 1.01 of the Current Agreement, the definition following the
defined term "Maturity Date" shall be deleted in full and replaced with the
following:

     "in the case of the Revolving Loan, means December 31, 2002, and in the
     case of the Term Loan, means September 10, 2002."

<PAGE>

     5. Section 2.06 of the Current Agreement is amended by replacing the phrase
"November 30, 2002" with the phrase "December 31, 2002".

     B. Effectiveness; Conditions. Borrowers shall have (i) delivered to Lender
a duly executed Revolving Credit Note substantially in the form attached hereto
as Exhibit A (the "Revolving Credit Note"), which Revolving Credit Note will
supersede and replace the existing Revolving Credit Note, dated October 31, 2002
and (ii) paid the Lender a fee of $10,000 in connection with the negotiating and
execution and effectiveness of this Amendment.

     C. Covenants. Borrowers hereby (i) covenant to pay or reimburse the Lender
for all of the Lender's costs and expenses, including fees and disbursements of
outside counsel and allocated in-house counsel, in connection with, or related
to, the negotiating and execution and effectiveness of this Amendment; and (ii)
acknowledge and agree that a failure to immediately do so will constitute an
Event of Default under the Agreement without further notice or other act of the
Lender.

     D. General.
        -------

     1. Except as specifically provided herein, all terms and conditions of the
Agreement remain in full force and effect, without waiver or modification.
Borrowers acknowledge that except as specifically provided in this Amendment,
nothing in this Amendment shall affect Borrowers' obligations under the
Agreement, which obligations remain valid, binding and enforceable, or shall
constitute a waiver by Lender of any of Lender's rights or remedies, now or at
any time in the future, with respect to any requirement under the Agreement or
with respect to an Event of Default or Default, occurring now or at any time in
the future.

     2. All terms defined in the Agreement shall have the same meaning when used
in this Amendment. This Amendment and the Agreement shall be read together as
one document. This Amendment may be executed in counterparts (and by different
parties hereto on different counterparts), each of which shall constitute an
original, but all of which when taken together shall constitute a single
document.

     3. The Borrowers hereby remake all representations and warranties contained
in the Agreement and reaffirm all covenants set forth therein. The Borrowers
further certify that as of the date of this Amendment, giving effect to the
provisions hereof, there exists no Event of Default as defined in the Agreement,
nor any condition, act or event which with the giving of notice or the passage
of time or both would constitute any such Event of Default.

                           [INTENTIONALLY LEFT BLANK]

                                       2
<PAGE>

     IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be
executed as of the date and year first written above.

HAUSER, INC.                            WELLS FARGO BANK, N.A.

By:  /s/  Thomas W. Hanlon              By: /s/  Art Brokx
     -----------------------------          ------------------
Name:   Thomas W. Hanlon                Name:   Art Brokx
Title:  Chief Financial Officer         Title:  Vice President

HAUSER TECHNICAL SERVICES, INC.

By:  /s/  Thomas W. Hanlon
     -----------------------------
Name:   Thomas W. Hanlon
Title:  Secretary and Treasurer

BOTANICALS INTERNATIONAL
EXTRACTS, INC.

By:  /s/  Thomas W. Hanlon
     -----------------------------
Name:   Thomas W. Hanlon
Title:  Chief Financial Officer

ZETAPHARM, INC.

By:  /s/  Thomas W. Hanlon
     -----------------------------
Name:   Thomas W. Hanlon
Title:  Secretary and Treasurer

<PAGE>

                                    EXHIBIT A

                              REVOLVING CREDIT NOTE
                               (follows this page)REVOLVING CREDIT NOTE

$8,700,000                                               Los Angeles, California
                                                               November 30, 2002

     FOR VALUE RECEIVED, the undersigned, HAUSER, INC., a Delaware corporation,
HAUSER TECHNICAL SERVICES, INC., a Delaware Corporation, BOTANICALS
INTERNATIONAL EXTRACTS, INC., a Delaware corporation, ZETAPHARM, INC., a New
York corporation, (collectively, the "Borrowers"), hereby jointly and severally,
unconditionally promise to pay to the order of Wells Fargo Bank, National
Association (the "Lender"), at c/o Wells Fargo Bank, N.A., 333 South Grand
Avenue, 9th Floor, Los Angeles, California 90071, or at such other place as the
holder of this Note may direct, on December 31, 2002 (the "Maturity Date") in
lawful money of the United States of America and in immediately available funds,
the principal amount of (a) EIGHT MILLION SEVEN HUNDRED THOUSAND DOLLARS
($8,700,000), or (b) such other amount as represents the aggregate unpaid
principal amount of all Revolving Loans made by the Lender pursuant to the
Credit Agreement (referred to below). The Borrowers further agree, jointly and
severally, to pay interest on the unpaid principal amount outstanding hereunder
from time to time from the date hereof in like money at such office at a rate
per annum equal to the Prime Rate plus a margin of four percent (4%). Interest
shall accrue hereunder from the date of each advance until the date of payment,
shall be calculated on the basis of a year of three hundred sixty (360) days and
shall be payable for the actual number of days elapsed (including the first day
but excluding the last day). Interest shall be payable in arrears on the last
day of each calendar month and on the Maturity Date. In the event of any
repayment or prepayment of any Loan, other than a prepayment prior to the
Maturity Date, accrued interest on the principal amount repaid or prepaid shall
be payable on the date of such repayment or prepayment.

     If any principal of or interest on any Loan or any fee or other amount
payable by the Borrowers hereunder or under the Credit Agreement is not paid
when due, whether at stated maturity, upon acceleration or otherwise, such
overdue amount shall bear interest, after as well as before judgment, at a rate
per annum equal to (i) in the case of overdue principal of any Loan, two percent
(2%) plus the rate otherwise applicable to such Loan as provided above in this
Note, or (ii) in the case of any other amount, the rate that would apply under
(i) of this paragraph if such amount constituted overdue principal.

     The holder of this Note is authorized to record on Schedule 1 annexed
hereto or on a continuation thereof the date, Type and amount of each Revolving
Loan made pursuant to the Credit Agreement, the date and amount of each payment
or repayment of principal

<PAGE>

thereof; provided, however, that the failure to make any such recordation shall
not affect the obligations of the Borrowers in respect of such Revolving Loans.

     This Note amends, restates and replaces the Revolving Credit Note
previously issued by Borrowers and referred to in the Amended and Restated
Credit Agreement by and between the Borrowers and the Lender dated as of
December 7, 2001, as amended (the "Credit Agreement"), is secured as provided
therein and in the Security Documents and is subject to optional and mandatory
prepayment as set forth in the Credit Agreement.

     Upon the occurrence of any one or more of the Events of Default specified
in the Credit Agreement, all amounts then remaining unpaid on this Note shall
become, or may be declared to be, immediately due and payable, all as provided
in the Credit Agreement.

     All parties now and hereafter liable with respect to this Note, whether
maker, principal, surety, guarantor, endorser or otherwise, hereby waive
presentment, demand, protest and all other notices of any kind.

     The holder of this Note is authorized from time to time to debit any
accounts maintained by any Borrower with such holder for any and all amounts
payable by the Borrowers hereunder.

     Terms defined in the Credit Agreement are used herein with their defined
meanings unless otherwise defined herein. This Note shall be governed by, and
construed and interpreted in accordance with, the laws of the State of
California.

     This Note may be executed in counterparts (and by different parties hereto
on different counterparts), each of which shall constitute an original, but all
of which when taken together shall constitute a single contract.

<PAGE>

     IN WITNESS WHEREOF, the parties hereto have caused this Revolving Credit
Note to be duly executed by their respective authorized officers as of the day
and year first above written.

HAUSER, INC.

By:  /s/  Thomas W. Hanlon
     --------------------------
Name:   Thomas W. Hanlon
Title:  Chief Financial Officer

HAUSER TECHNICAL SERVICES, INC.

By:  /s/  Thomas W. Hanlon
     --------------------------
Name:   Thomas W. Hanlon
Title:  Secretary and Treasurer

BOTANICALS INTERNATIONAL EXTRACTS, INC.

By:  /s/  Thomas W. Hanlon
     --------------------------
 Name:   Thomas W. Hanlon
 Title:  Chief Financial Officer

ZETAPHARM, INC.

By:  /s/  Thomas W. Hanlon
     --------------------------
  Name:   Thomas W. Hanlon
  Title:  Secretary and Treasurer

<PAGE>

                                                                      SCHEDULE 1
                                                        TO REVOLVING CREDIT NOTE

                      LOANS AND PAYMENTS OF REVOLVING LOAN
                      ------------------------------------

================================================================================
                                                Unpaid
            Amount of                          Principal
              Loans                            Balance of
Date                         Amount of          Loans            Notation
                         Principal Repaid                        Made By

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