Document:

Exhibit
        10.37

    

  SECOND AMENDMENT
    TO LEASE

   

  THIS SECOND AMENDMENT
    TO LEASE (this “Second Amendment”) is made as of August 28 2012, by and between ARE-SEATTLE NO. 17,
      LLC, a Delaware limited liability company (“Landlord”), and KINETA, INC., a Washington corporation
    (“Tenant”).

   

  RECITALS

   

  A.       

  Landlord
    and Tenant are now parties to that certain Lease dated as of November 19, 2010 as amended by that certain First Amendment
    to Lease dated as of August 12, 2012 (as amended, the “Lease”). Pursuant to the Lease, Tenant leases certain
    premises (“Premises”) located at 219 Terry Avenue, Seattle, Washington. The Premises are more particularly described
    in the Lease. Capitalized terms used herein without definition shall have the meanings defined for such terms in the Lease.

   

  B.       

  Landlord
    and Tenant desire to amend the Lease to change the Adjustment Date from each annual anniversary of the Commencement Date to each
    annual anniversary of the Rent Commencement Date, subject to the terms and conditions set forth below.

   

  NOW, THEREFORE,
    in consideration of the foregoing Recitals, which are incorporated herein by this reference, the mutual promises and conditions
    contained herein, and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged,
    Landlord and Tenant hereby agree as follows:

   

  1.          Base
        Rent Adjustments. The first sentence of Section 4 of the Lease is hereby deleted
    in its entirety and replaced with the following: “Base Rent shall be increased on each annual anniversary of the Rent Commencement
    Date (each an “Adjustment Date”) by multiplying the Base Rent payable immediately before such Adjustment Date
    by the Rent Adjustment Percentage and adding the resulting amount to the Base Rent payable immediately before such Adjustment Date.”

   

  2.          Miscellaneous.

   

  a.            
    

  This Second Amendment is
    the entire agreement between the parties with respect to the subject matter hereof and supersedes
    all prior and contemporaneous oral and written agreements and discussions. This Second Amendment may be amended only by an agreement
    in writing, signed by the parties hereto.

   

  b.           
    

  This Second Amendment is
    binding upon and shall inure to the benefit of the parties hereto, their respective agents, employees,
    representatives, officers, directors, divisions, subsidiaries, affiliates, assigns, heirs, successors in interest and shareholders.

   

  c.            
    

  This Second Amendment may
    be executed in any number of counterparts, each of which shall be deemed an original, but all
    of which when taken together shall constitute one and the same instrument. The signature page of any counterpart may be detached
    therefrom without impairing the legal effect of the signature(s) thereon provided such signature page is attached to any other
    counterpart identical thereto except having additional signature pages executed by other parties to this Second Amendment attached
    thereto.

   

  
     

    
      

    

  

   

  d.           
    

  Except as amended and/or
    modified by this Second Amendment, the Lease is hereby ratified and confirmed and all other terms
    of the Lease shall remain in full force and effect, unaltered and unchanged by this Second Amendment. In the event of any conflict
    between the provisions of this Second Amendment and the provisions of the Lease, the provisions of this Second Amendment shall
    prevail. Whether or not specifically amended by this Second Amendment, all of the terms and provisions of the Lease are hereby
    amended to the extent necessary to give effect to the purpose and intent of this Second Amendment.

   

  [Signatures
    are on the next page.]

   

  
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  IN WITNESS WHEREOF,
    the parties hereto have executed this Second Amendment as of the day and year first above written.

   

  

  	 	TENANT:
	 	 	 	 
	 	KINETA, INC.,
	 	a Washington corporation
	 	 	 	 
	 	By:	/s/ Campion Fellin
	 	Its:	Vice President of Operations
	 	 	 	 
	 	LANDLORD:
	 	 	 	 
	 	ARE-SEATTLE NO. 17, LLC,
	 	a Delaware limited liability company
	 	 	 	 
	 	By:	 	ALEXANDRIA REAL ESTATE EQUITIES, L.P., a Delaware limited partnership, managing member
	 	 	 	 
	 	By:	 	ARE-QRS CORP.,
	 	 	 	a Maryland corporation,
	 	 	 	general partner
	 	 	 	 
	 	By:	/s/ Jackie Clem
	 	Its:	Vice President, Real Estate Legal AffairsExhibit 10.38

   

  THIRD AMENDMENT TO LEASE

   

  THIS THIRD AMENDMENT TO LEASE (this “Third Amendment”) is made as of February 28, 2013, by and between ARE-SEATTLE NO. 17, LLC, a
    Delaware limited liability company (“Landlord”), and KINETA, INC., a Washington corporation (“Tenant”).

   

  RECITALS

   

  A.            

  Landlord and Tenant are now
    parties to that certain Lease Agreement dated as of November 19, 2010, as amended by that certain First Amendment to Lease dated as of August 12, 2011, and as further amended by that certain Second Amendment to Lease dated as of August 28, 2012 (as
    amended, the “Lease”). Pursuant to the Lease, Tenant leases certain premises (“Original Premises”) consisting of approximately 10,461 rentable square feet located in that certain real property located at 219 Terry Avenue North, Seattle,
    Washington (“Building”). The Original Premises are more particularly described in the Lease. Capitalized terms used herein without definition shall have the meanings defined for such terms in the Lease.

   

  B.           
      

   Landlord and Tenant desire, subject to the terms and conditions set forth below, to amend the Lease to, among other things, (i) expand the size of the Premises by
    adding approximately 1,643 rentable square feet of space located on the basement floor of the Building, and (ii) revise the rentable square footage of the Project.

   

  NOW, THEREFORE, in consideration of the foregoing Recitals, which are incorporated herein by this reference, the mutual promises and
    conditions contained herein, and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Landlord and Tenant hereby agree as follows:

   

  	1.	Expansion Premises. In addition to the Original Premises, commencing on the Expansion Premises Commencement Date (as defined below), Landlord leases to Tenant, and Tenant leases from Landlord, that
          certain portion of the Building commonly known as Suites B-3 and B-4, consisting of approximately 1,643 rentable square feet, as shown on Exhibit A attached hereto (the “Expansion Premises”).

   

  	2.	Delivery. Landlord shall deliver the Expansion Premises to Tenant on March 1, 2013 (“Expansion Premises Commencement Date”). The “Expansion Premises Rent Commencement Date” shall be
          June 1, 2013.

   

  Except as set forth in this Third Amendment: (i) Tenant shall accept the Expansion Premises in their condition as of the Expansion Premises Commencement
    Date; (ii) Landlord shall have no obligation for any defects in the Expansion Premises; and (iii) Tenant’s taking possession of the Expansion Premises shall be conclusive evidence that Tenant accepts the Expansion Premises and that the Expansion
    Premises were in good condition at the time possession was taken.

   

  Upon request of Landlord, Tenant shall execute and deliver a written acknowledgment of the Expansion Premises Commencement Date in a form substantially
    similar to the form of the “Acknowledgement of Commencement Date” attached to the Lease as Exhibit D; provided, however, Tenant’s failure to execute and deliver such acknowledgment shall not affect Landlord’s rights hereunder.

   

  
     

    
      
 

  

   

  Tenant agrees and acknowledges that neither Landlord nor any agent of Landlord has made any representation or warranty with respect to the condition of all
    or any portion of the Expansion Premises, and/or the suitability of the Expansion Premises for the conduct of Tenant’s business, and Tenant waives any implied warranty that the Expansion Premises are suitable for the Permitted Use.

   

  	3.	Premises. Commencing on the Expansion Premises Commencement Date, the defined terms “Premises” and “Rentable Area of Premises” on page 1 of the Lease are deleted in their entirety and
          replaced with the following:

   

  “Premises: That portion of the Building containing approximately 12,104 rentable square feet, consisting of the (i) “Original Premises”
    containing approximately 9,390 rentable square feet consisting of the entire top floor of the Building and approximately 1,071 rentable square feet located in the basement of the Building, and (ii) “Expansion Premises” containing approximately
    1,643 rentable square feet located in the basement of the Building, all as determined by Landlord, as shown on Exhibit A.”

   

  As of the Expansion Premises Commencement Date, Exhibit A to the Lease shall be amended to include the Expansion Premises as shown on Exhibit A
    attached to this Third Amendment.

   

  	4.	Base Term. Commencing on the Expansion Premises Commencement Date, the defined term “Base Term” on page 1 of the Lease is deleted in its entirety and replaced with the following:

   

  “Base Term: A term beginning (i) with respect to the Original Premises, on the Commencement Date, (ii) with respect to the Expansion Premises, on the
    Expansion Premises Commencement Date, and ending with respect to the entire Premises on February 28, 2017.”

   

  	5.	Base Rent.

   

  a.            

  Original Premises.
    Tenant shall continue to pay Base Rent with respect to the Original Premises as set forth in the Lease.

   

  b.            

  Expansion Premises. Commencing on the Expansion Premises Rent Commencement Date, Tenant shall pay Base Rent for the Expansion Premises at the same rate per rentable square foot per
    month that Tenant is then paying for the Original Premises, as increased during the Base Term as provided for in Section 4 of the Lease.

   

  Notwithstanding anything to the contrary contained herein, for the period commencing on the Expansion Premises Rent Commencement Date through May 31, 2014,
    in addition to the Base Rent payable in connection with the Original Premises, Tenant shall only be required to pay Base Rent with respect to 807 rentable square feet of the Expansion Premises. Commencing on June 1, 2014, Tenant shall commence, in
    addition to the Base Rent payable in connection with the Original Premises, paying Base Rent with respect to the entire Expansion Premises.

   

  
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  	6.	Rentable Area of Project. As of the date of this Third Amendment, the defined term “Rentable Area of the Project” on page 1 of the Lease is deleted in its entirety and replaced with the
          following:

   

  “Rentable Area of Project: 30,960 sq. ft.”

   

  	7.	Tenant’s Share of Operating Expenses. Commencing on the Expansion Premises Commencement Date, the defined term “Tenant’s Share of Operating Expenses” on page 1 of the Lease is hereby deleted in
          its entirety and replaced with the following:

   

  “Tenant’s Share of Operating Expenses: 39.096%”

   

  Notwithstanding anything to the contrary contained herein, for the period commencing on the Expansion Premises Commencement Date through February 28, 2014,
    in addition to the Operating Expenses payable in connection with the Original Premises, Tenant shall only be required to pay Operating Expenses with respect to 807 rentable square feet of the Expansion Premises. During such period, Tenant Share of
    Operating Expenses shall be equal to 36.395%. Commencing on March 1, 2014, Tenant shall commence paying Operating Expenses with respect to the entire Premises.

   

  	8.	Miscellaneous.

   

  a.            

  This Third Amendment is the entire agreement between the parties with respect to the subject matter hereof and supersedes all prior and contemporaneous oral and written agreements and discussions.
    This Third Amendment may be amended only by an agreement in writing, signed by the parties hereto.

   

  b.            

  This Third Amendment is
    binding upon and shall inure to the benefit of the parties hereto, their respective agents and assigns.

   

  c.            

  This Third Amendment may be
    executed in any number of counterparts, each of which shall be deemed an original, but all of which when taken together shall constitute one and the same instrument. The signature page of any counterpart may be detached therefrom without impairing the
    legal effect of the signature(s) thereon provided such signature page is attached to any other counterpart identical thereto except having additional signature pages executed by other parties to this Third Amendment attached thereto.

   

  d.            

  Except as amended and/or
    modified by this Third Amendment, the Lease is hereby ratified and confirmed and all other terms of the Lease shall remain in full force and effect, unaltered and unchanged by this Third Amendment. In the event of any conflict between the provisions of
    this Third Amendment and the provisions of the Lease, the provisions of this Third Amendment shall prevail. Whether or not specifically amended by this Third Amendment, all of the terms and provisions of the Lease are hereby amended to the extent
    necessary to give effect to the purpose and intent of this Third Amendment.

   

  [Signatures are on the next page.]

   

  
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  IN WITNESS WHEREOF, the parties hereto have executed this Third Amendment as of the day and year first above written.

   

  

  	 	TENANT:
	 	 	 	 	 	 
	 	KINETA, INC.,
	 	a Washington corporation
	 	 	 	 	 	 
	 	By:	/s/ Campion Fellin
	 	Its:	Vice President of Operations
	 	 	 	 	 	 
	 	LANDLORD:
	 	 	 	 	 	 
	 	ARE-SEATTLE NO. 17, LLC,
	 	a Delaware limited liability company
	 	 	 	 	 	 
	 	By:	 	ALEXANDRIA REAL ESTATE EQUITIES, L.P., a
	 	 	 	Delaware limited partnership,
	 	 	 	managing member
	 	 	 	 	 	 
	 	 	 	By:	ARE-QRS CORP.,
	 	 	 	 	a Maryland corporation,
	 	 	 	 	general partner
	 	 	 	 	 	 
	 	 	 	 	By:	/s/ Eric S. Johnson
	 	 	 	 	Its:	Vice President, Real Estate Legal Affairs

   

  
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  Exhibit A

   

  Expansion Premises

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