Document:

Offer Letter Agreement

 EXHIBIT 10.21 
 [ZELTIQ LOGO] 
 June 14, 2010 
 Richard Poinsett 
 6534 Emory Drive 
 Hickory, North Carolina 28601 
 Re: EMPLOYEE OFFER
LETTER 
 Dear Richard: 

ZELTIQ AESTHETICS, INC. (the “Company”) is
pleased to offer you the position of Vice President of Operations, reporting to Gordie Nye, President and CEO. You will perform duties customarily associated with your position and such other duties as may be assigned by the President and CEO or
designate. You will be based at the Company’s offices in Pleasanton, CA, or such other location to which the Company headquarters may relocate. By signing this letter agreement, you represent and warrant to the Company that you are under no
contractual commitments inconsistent with your obligations to the Company. 
 1.
COMPENSATION. 
 (a) Base Salary. You will be
paid a salary at the annual rate of $230,000 payable in semi-monthly installments or otherwise in accordance with the Company’s standard payroll practices for salaried employees. This salary may be subject to adjustment pursuant to the
Company’s employee compensation policies in effect from time to time. 

(b) Stock Options. Company’s management will recommend to the
Company’s Board of Directors that you be granted an option (the “Stock Option”) to purchase 500,000 shares of the Company’s Common Stock. The exercise price per share will be equal to the fair market value per share on the date
the option is granted or on your first day of employment, whichever is later. The Stock Option shall vest over four (4) years with one-fourth (1/4) of the options vesting at the end of twelve (12) months, and the remainder vesting
monthly at a rate of 1/48th of the total number per month
thereafter until all shares are vested. The Stock Option shall be an incentive stock option to the extent permitted by applicable law. The Stock Option will be subject to the terms and conditions applicable to options granted under the
Company’s 2005 Equity Incentive Plan, and as described in that plan and the applicable stock option agreement. 
 (c) Company Bonus. You are eligible to earn an annual bonus of $57,000, 25% of your base salary, pro-rated upon date of hire and based upon the company 2010 Management Bonus Plan.

 (d) Relocation. In addition to your Base Salary, you will receive a one-time
Relocation Bonus in the amount of $25,000, subject to all withholdings to be included in your first pay check. Additionally, the company will directly pay for all travel for you and your family from North Carolina to California and temporary housing
and car rental up to 60 days. 
 (e) Sale of Home. You are also eligible to receive
reimbursement of the brokerage and closing costs on the sale price of your home in North Carolina not to exceed $20,000, payable after 6 months of and up to 24 months of employment with Zeltiq. If your employment is terminated voluntarily or for
cause within your first year of employment you will be required to repay the Company any reimbursement associated with the sale of your home. 

 2. BENEFITS. You shall be entitled to
the Company’s basic employment benefits available to all Company employees, as the same currently exist or may exist in the future. You acknowledge that participation in Company benefit programs may require payroll deductions and/or direct
contributions by you. 
 3. EMPLOYMENT TERMS. Your
employment relationship with the Company will be governed by the general employment policies and practices of the Company. You will be required as a condition to your employment with the Company, to (i) acknowledge your receipt and
understanding, sign and abide by the Company’s standard Confidential Information and Invention Assignment Agreement, attached hereto as Exhibit A; (ii) sign and return a satisfactory I-9 Immigration form providing sufficient
documentation establishing your employment eligibility in the United States, and (iii) provide satisfactory proof of your identity as required by United States law. Your duties under the Confidential Information and Invention Assignment
Agreement shall survive termination of your employment with the Company. By signing this letter, you acknowledge that a remedy at law for any breach or threatened breach by you of the provisions of the Confidential Information and Invention
Assignment Agreement would be inadequate, and you therefore agree that the Company shall be entitled to injunctive relief in case of any such breach or threatened breach. 

4. AT-WILL EMPLOYMENT. Your employment with the
Company will be “at-will,” meaning that either you or the Company will be entitled to terminate your employment at any time and for any or no reason, with or without cause. Although your job duties, title, compensation and benefits, as
well as the Company’s personnel policies and procedures, may change from time to time, the “at will” nature of your employment may only be changed in an express written agreement signed by you and a duly authorized officer of the
Company. Your participation in any stock purchase or benefit program is not to be regarded as assuring you continuing employment for any particular period of time. 

5. OUTSIDE ACTIVITIES. While you render services to the Company, you
will not engage in any other gainful employment, business or activity without the written consent of the Company. While you render services to the Company, you also will not assist any person or organization in competing with the Company, in
preparing to compete with the Company or in hiring any employees of the Company. During the term of your employment by the Company, except on behalf of the Company, you shall not directly or indirectly, whether as an officer, director, stockholder,
partner, proprietor, associate, representative, consultant, or in any capacity whatsoever engage in, become financially interested in, be employed by or have any business connection with any other person, corporation, firm, partnership or other
entity whatsoever which were known by you to compete directly with the Company, throughout the world, in any line of business engaged in (or planned to be engaged in) by the Company; provided, however, that anything above to the contrary
notwithstanding, you may own, as a passive investor, securities of any competitor corporation, so long as your direct holdings in any one such corporation shall not in the aggregate constitute more than 1% of the voting stock of such corporation.

 6. SATISFACTORY REFERENCE CHECKS. This
offer is contingent upon completion of professional reference checks by the Company, at its discretion and to its satisfaction. 
 7. START DATE. Your start date shall be on June 21, 2010. This offer, if not accepted, will expire at the close of business on June 18, 2010.

 8. ENTIRE AGREEMENT. This offer letter sets forth the
full and complete agreement between you and the Company regarding your employment with the Company. Any additional or contrary terms, representations, offers or agreements, whether written or oral, that may have been made to you are hereby revoked
and superseded in their entirety by this offer. 

  
 2 

 We hope that you find the foregoing terms acceptable. You may indicate your
agreement with these terms and accept this offer by signing and dating both the enclosed duplicate original of this letter and the enclosed Employee Proprietary Information and Inventions Agreement and returning them to me. 

If you have any questions, please call Gordie Nye, (925) 474-2569 

 

	
	Very truly yours,
	
	 /s/ John Howe

	 John Howe, Chief Financial Officer

 AGREED AND ACCEPTED 
  

	
	 I have read and accept this employment offer:

	
	 /s/ Richard Poinsett

	 Richard Poinsett

	 Dated: 6-18, 2010

  
 3 

 [ZELTIQ LOGO] 
 Exhibit A 
 CONFIDENTIAL INFORMATION AND 

INVENTION ASSIGNMENT AGREEMENT 
 As a condition of my becoming employed (or my employment being continued) or retained as a consultant (or my consulting relationship being continued) by Zeltiq Aesthetics, Inc., a Delaware corporation,
with any of its current or future subsidiaries, affiliates, successors or assigns (collectively, the “Company”), and in consideration of my employment or consulting relationship with the Company and my receipt of the compensation
now and hereafter paid to me by the Company, I agree to the following: 
 1. Employment or Consulting
Relationship. I understand and acknowledge that this Agreement does not alter, amend or expand upon any rights I may have to continue in the employ of, or in a consulting relationship with, or the duration of my employment or consulting
relationship with, the Company under any existing agreements between the Company and me or under applicable law. Any employment or consulting relationship between the Company and me, whether commenced prior to or upon the date of this Agreement,
shall be referred to herein as the “Relationship.” 
 2. At-Will Employment. I
understand and acknowledge that my Relationship with the Company is and shall continue to be at-will, as defined under applicable law, meaning that either I or the Company may terminate the Relationship at any time for any reason or no reason,
without further obligation or liability. 
 3. Confidential Information. 

(a) Company Information. I agree at all times during the term of my Relationship with the
Company and thereafter, to hold in strictest confidence, and not to use, except for the benefit of the Company, or to disclose to any person, firm, corporation or other entity without written authorization of the Board of Directors of the Company,
any Confidential Information of the Company which I obtain or create. I further agree not to make copies of such Confidential Information except as authorized by the Company. I understand that “Confidential Information” means any
Company proprietary information, technical data, trade secrets or know-how, including, but not limited to, research, product plans, products, services, suppliers, customer lists and customers (including, but not limited to, customers of the Company
on whom I called or with whom I became acquainted during the Relationship), prices and costs, markets, software, developments, inventions, laboratory notebooks, processes, formulas, technology, designs, drawings, engineering, hardware configuration
information, marketing, licenses, finances, budgets or other business information disclosed to me by the Company either directly or indirectly in writing, orally or by drawings or observation of parts or equipment or created by me during the period
of the Relationship, whether or not during working hours, and any information pertaining to any aspects of the Company’s business which is either information not known by actual or potential competitors of the Company or is proprietary
information of the 

 
Company or its customers or suppliers, whether of a technical nature or otherwise. I further understand that Confidential Information does not include any of the foregoing items which has become
publicly and widely known and made generally available through no wrongful act of mine or of others who were under confidentiality obligations as to the item or items involved. 

(b) Former Employer Information. I represent that my performance of all terms of this
Agreement as an employee or consultant of the Company have not breached and will not breach any agreement to keep in confidence proprietary information, knowledge or data acquired by me in confidence or trust prior or subsequent to the commencement
of my Relationship with the Company, and I will not disclose to the Company, or induce the Company to use, any inventions, confidential or proprietary information or material belonging to any previous employer or any other party. 

(c) Third Party Information. I recognize that the Company has received and in the future
will receive from third parties their confidential or proprietary information subject to a duty on the Company’s part to maintain the confidentiality of such information and to use it only for certain limited purposes. I agree to hold all such
confidential or proprietary information in the strictest confidence and not to disclose it to any person, firm or corporation or to use it except as necessary in carrying out my work for the Company consistent with the Company’s agreement with
such third party. 
 4. Inventions. 

(a) Inventions Retained and Licensed. I have attached hereto, as Exhibit A, a list
describing with particularity all inventions, original works of authorship, developments, improvements, and trade secrets which were made by me prior to the commencement of the Relationship (collectively referred to as “Prior
Inventions”), which belong solely to me or belong to me jointly with another, which relate in any way to any of the Company’s proposed businesses, products or research and development, and which are not assigned to the Company
hereunder; or, if no such list is attached, I represent that there are no such Prior Inventions. If, in the course of my Relationship with the Company, I incorporate into a Company product, process or machine a Prior Invention owned by me or in
which I have an interest, the Company is hereby granted and shall have a non-exclusive, royalty-free, irrevocable, perpetual, worldwide license (with the right to sublicense) to make, have made, copy, modify, make derivative works of, use, sell and
otherwise distribute such Prior Invention as part of or in connection with such product, process or machine. 
 (b) Assignment of Inventions. I agree that I will promptly make full written disclosure to the Company, will hold in trust for the sole right and benefit of the Company, and hereby assign to
the Company, or its designee, all my right, title and interest throughout the world in and to any and all inventions, original works of authorship, developments, concepts, know-how, improvements or trade secrets, whether or not patentable or
registrable under copyright or similar laws, which I may solely or jointly conceive or develop or reduce to practice, or cause to be conceived or developed or reduced to practice, during the period of time in which I am employed by or a consultant
of the Company (collectively referred to as “Inventions”), except as provided in Section 4(e) below. I further acknowledge that all inventions, original works of authorship, developments, concepts, know-how, improvements or

 
trade secrets which are made by me (solely or jointly with others) within the scope of and during the period of my Relationship with the Company are “works made for hire” (to the
greatest extent permitted by applicable law) and are compensated by my salary (if I am an employee) or by such amounts paid to me under any applicable consulting agreement or consulting arrangements (if I am a consultant), unless regulated otherwise
by the mandatory law of the state of California. 
 (c) Maintenance of Records. I
agree to keep and maintain adequate and current written records of all Inventions made by me (solely or jointly with others) during the term of my Relationship with the Company. The records may be in the form of notes, sketches, drawings, flow
charts, electronic data or recordings, laboratory notebooks, and any other format. The records will be available to and remain the sole property of the Company at all times. I agree not to remove such records from the Company’s place of
business except as expressly permitted by Company policy which may, from time to time, be revised at the sole election of the Company for the purpose of furthering the Company’s business. 

(d) Patent and Copyright Rights. I agree to assist the Company, or its designee, at the
Company’s expense, in every proper way to secure the Company’s rights in the Inventions and any copyrights, patents, trademarks, mask work rights, moral rights, or other intellectual property rights relating thereto in any and all
countries, including the disclosure to the Company of all pertinent information and data with respect thereto, the execution of all applications, specifications, oaths, assignments, recordations, and all other instruments which the Company shall
deem necessary in order to apply for, obtain, maintain and transfer such rights and in order to assign and convey to the Company, its successors, assigns and nominees the sole and exclusive rights, title and interest in and to such Inventions, and
any copyrights, patents, mask work rights or other intellectual property rights relating thereto. I further agree that my obligation to execute or cause to be executed, when it is in my power to do so, any such instrument or papers shall continue
after the termination of this Agreement until the expiration of the last such intellectual property right to expire in any country of the world. If the Company is unable because of my mental or physical incapacity or unavailability or for any other
reason to secure my signature to apply for or to pursue any application for any United States or foreign patents or copyright registrations covering Inventions or original works of authorship assigned to the Company as above, then I hereby
irrevocably designate and appoint the Company and its duly authorized officers and agents as my agent and attorney in fact, to act for and in my behalf and stead to execute and file any such applications and to do all other lawfully permitted acts
to further the application for, prosecution, issuance, maintenance or transfer of letters patent or copyright registrations thereon with the same legal force and effect as if originally executed by me. I hereby waive and irrevocably quitclaim to the
Company any and all claims, of any nature whatsoever, which I now or hereafter have for infringement of any and all proprietary rights assigned to the Company. 

(e) Exception to Assignments. I understand that the provisions of this Agreement requiring
assignment of Inventions to the Company do not apply to any invention which qualifies fully under the provisions of California Labor Code Section 2870 (attached hereto as Exhibit B). I will advise the Company promptly in writing of any
inventions that I believe meet such provisions and are not otherwise disclosed on Exhibit A. 

 5. Returning Company Documents. I agree that, at the time of
termination of my Relationship with the Company, I will deliver to the Company (and will not keep in my possession, recreate or deliver to anyone else) any and all devices, records, data, notes, reports, proposals, lists, correspondence,
specifications, drawings, blueprints, sketches, laboratory notebooks, materials, flow charts, equipment, other documents or property, or reproductions of any aforementioned items developed by me pursuant to the Relationship or otherwise belonging to
the Company, its successors or assigns. I further agree that to any property situated on the Company’s premises and owned by the Company, including disks and other storage media, filing cabinets or other work areas, is subject to inspection by
Company personnel at any time with or without notice. In the event of the termination of the Relationship, I agree to sign and deliver the “Termination Certification” attached hereto as Exhibit C. 

6. Notification to Other Parties. 

(a) Employees. In the event that I leave the employ of the Company, I hereby consent to
notification by the Company to my new employer about my rights and obligations under this Agreement. 
 (b) Consultants. I hereby grant consent to notification by the Company to any other parties besides the Company with whom I maintain a consulting relationship, including parties with whom
such relationship commences after the effective date of this Agreement, about my rights and obligations under this Agreement. 
 7. Solicitation of Employees, Consultants and Other Parties. I agree that during the term of my Relationship with the Company, and for a period of twelve (12) months immediately
following the termination of my Relationship with the Company for any reason, whether with or without cause, I shall not either directly or indirectly solicit, induce, recruit or encourage any of the Company’s employees or consultants to
terminate their relationship with the Company, or take away such employees or consultants, or attempt to solicit, induce, recruit, encourage or take away employees or consultants of the Company, either for myself or for any other person or entity.
Further, for a period of twelve (12) months following termination of my Relationship with the Company for any reason, with or without cause, I shall not solicit any licensor to or customer of the Company or licensee of the Company’s
products, in each case, that are known to me, with respect to any business, products or services that are competitive to the products or services offered by the Company or under development as of the date of termination of my Relationship with the
Company. 
 8. Representations and Covenants. 

(a) Facilitation of Agreement. I agree to execute promptly any proper oath or verify any
proper document required to carry out the terms of this Agreement upon the Company’s written request to do so. 
 (b) Conflicts. I represent that my performance of all the terms of this Agreement will not breach any agreement to keep in confidence proprietary information acquired by me in confidence or
in trust prior to commencement of my Relationship with the Company. I 

 
have not entered into, and I agree I will not enter into, any oral or written agreement in conflict with any of the provisions of this Agreement. 

(c) Voluntary Execution. I certify and acknowledge that I have carefully read all of the
provisions of this Agreement and that I understand and will fully and faithfully comply with such provisions. 

9. General Provisions. 

(a) Governing Law. The validity, interpretation, construction and performance of this
Agreement shall be governed by the laws of the State of California, without giving effect to the principles of conflict of laws. 
 (b) Entire Agreement. This Agreement sets forth the entire agreement and understanding between the Company and me relating to the subject matter herein and merges all prior discussions
between us. No modification or amendment to this Agreement, nor any waiver of any rights under this Agreement, will be effective unless in writing signed by the party to be charged. Any subsequent change or changes in my duties, obligations, rights
or compensation will not affect the validity or scope of this Agreement. 
 (c)
Severability. If one or more of the provisions in this Agreement are deemed void by law, then the remaining provisions will continue in full force and effect. 

(d) Successors and Assigns. This Agreement will be binding upon my heirs, executors,
administrators and other legal representatives and will be for the benefit of the Company, its successors, and its assigns. 
 (e) Survival. The provisions of this Agreement shall survive the termination of the Relationship and the assignment of this Agreement by the Company to any successor in interest or other
assignee. 
 (f) ADVICE OF COUNSEL. I ACKNOWLEDGE THAT, IN EXECUTING THIS
AGREEMENT, I HAVE HAD THE OPPORTUNITY TO SEEK THE ADVICE OF INDEPENDENT LEGAL COUNSEL, AND I HAVE READ AND UNDERSTOOD ALL OF THE TERMS AND PROVISIONS OF THIS AGREEMENT. THIS AGREEMENT SHALL NOT BE CONSTRUED AGAINST ANY PARTY BY REASON OF THE
DRAFTING OR PREPARATION HEREOF. 
 [Signature Page Follows] 

 The parties have executed this Agreement on the respective dates set forth
below: 
  

									
	 COMPANY:
	 		 	 EMPLOYEE:

			
	ZELTIQ AESTHETICS, INC.	 		 	 RICHARD POINSETT, an Individual:

			
	 /s/ Gordie Nye
	 		 	 /s/ Richard Poinsett

	 Signature
	 		 	 Signature

		 		 	
				
	 By:
	 	 	 		 	 Richard Poinsett

	  
 Title:
	 		 		 	 Printed Name

					
	 Date:
	 	 	 		 	 Date:
	 	 6-18-10

			
	 Address: 4698 Willow Road

      Pleasanton, CA 94588
	 		 	 Address: 6534 Emory Dr.

      Hickory, NC 28601

 EXHIBIT A 

LIST OF PRIOR INVENTIONS 
 AND ORIGINAL WORKS OF AUTHORSHIP 
 EXCLUDED FROM SECTION 4 

 

					
	
        Title        
	 	
        Date        
	 	 Identifying
Number or
Brief
        Description        

  

	X	 No inventions or improvements 

  

	    	 Additional Sheets Attached 

			
		
	Signature of Employee/Consultant	 	/s/ Richard Poinsett
		
	Print Name of Employee/Consultant:	 	Richard Poinsett
		
	 Date: 6-18-10
	 	

 [ZELTIQ LOGO] 
 EXHIBIT B 
 Section 2870 of the California Labor Code is as
follows: 
 (a) Any provision in an employment agreement which provides that an employee shall assign, or offer
to assign, any of his or her rights in an invention to his or her employer shall not apply to an invention that the employee developed entirely on his or her own time without using the employer’s equipment, supplies, facilities, or trade secret
information except for those inventions that either: 
 (1) Relate at the time of conception or
reduction to practice of the invention to the employer’s business, or actual or demonstrably anticipated research or development of the employer; or 

(2) Result from any work performed by the employee for the employer. 

(b) To the extent a provision in an employment agreement purports to require an employee to assign an invention otherwise
excluded from being required to be assigned under subdivision (a), the provision is against the public policy of this state and is unenforceable. 

 EXHIBIT C 

TERMINATION CERTIFICATION 
 This is to certify that I do not have in my possession, nor have I failed to return, any devices, records, data, notes, reports, proposals, lists, correspondence, specifications, drawings, blueprints,
sketches, laboratory notebooks, flow charts, materials, equipment, other documents or property, or copies or reproductions of any aforementioned items belonging to Zeltiq Aesthetics, Inc., its subsidiaries, affiliates, successors or assigns
(together the “Company”). 
 I further certify that I have complied with all the terms of the
Company’s Confidential Information and Invention Assignment Agreement signed by me, including the reporting of any inventions and original works of authorship (as defined therein), conceived or made by me (solely or jointly with others) covered
by that agreement. 
 I further agree that, in compliance with the Confidential Information and Invention
Assignment Agreement, I will preserve as confidential all trade secrets, confidential knowledge, data or other proprietary information relating to products, processes, know-how, designs, formulas, developmental or experimental work, computer
programs, data bases, other original works of authorship, customer lists, business plans, financial information or other subject matter pertaining to any business of the Company or any of its employees, clients, consultants or licensees. 

I further agree that for twelve (12) months from the date of this Certificate, I shall not either directly or
indirectly solicit, induce, recruit or encourage any of the Company’s employees or consultants to terminate their relationship with the Company, or take away such employees or consultants, or attempt to solicit, induce, recruit, encourage or
take away employees or consultants of the Company, either for myself or for any other person or entity. Further, for a period of twelve (12) months from the date of this Certificate, I shall not solicit any licensor to or customer of the
Company or licensee of the Company’s products, in each case, that are known to me, with respect to any business, products or services that are competitive to the products or services offered by the Company or under development as of the date of
termination of my Relationship with the Company. 
  

					
	 Date:
                                    
	 		 	
			
	 	 		 	  
		 		 	 (Employee’s Signature)

			
	 	 		 	  
		 		 	 (Type/Print Employee’s Name)Severance Agreement

 EXHIBIT 10.22 
 [ZELTIQ Logo] 
 December 3, 2010 
 Mitch Levinson 
 5658 Owens Drive, Apt. 308 

Pleasanton, CA 94588 
 Re:
Separation from Zeltiq Aesthetics, Inc. 
 Dear Mitch: 
 This letter confirms your termination from Zeltiq Aesthetics, Inc. (the “Company”) effective December 3, 2010 (“Separation Date”), and explains the details of your
separation from employment as well as the severance benefits the Company is offering to you. 
 You acknowledge that you have
been given your final paycheck and paid all outstanding salary amounts and any accrued, but unused, vacation time. You also will be eligible to convert your medical insurance coverage under COBRA, and will be provided with information describing
this conversion election. 
 Per the terms of our April 15, 2010 agreement, the Company will provide to you the following
severance benefits in exchange for your agreement to waive all claims against the Company, whether you have any claims or not: 

(i) Severance. The Company will pay you severance in the amount of $155,000.04, less applicable withholdings, which is equivalent
to six (6) months of your current base salary and payable in the form of salary continuation (“Severance”). The Severance will start being paid on the Company’s first payroll following expiration of the 7-day revocation
period discussed below. 
 (ii) Bonus. In addition, the Company will pay you a bonus payment of $77,500, less applicable
withholdings, which is equivalent to 25% of your current base salary (“Bonus Payment”). The Bonus Payment will be included in your first payroll payment. 
 (iii) Continued and Accelerated Vesting. The stock options granted to you by the Company pursuant to the Company’s 2005 Stock Option Plan (“Plan”) will continue to vest until
the second anniversary of your Separation Date (the “Continued Vesting Period”); provided that, during the Continued Vesting Period, you do not engage in any behavior that constitutes “Cause,” as that term is defined in
your employment agreement with the Company dated April 15, 2010 (“Employment Agreement”). Upon your successful completion of the Continued Vesting Period, all outstanding options held by you will vest automatically and the
exercise period for these vested options and all other 

 
vested options will extend to the earlier of the option’s expiration date or the five year anniversary of your Separation Date; provided, however, that such options will be treated as
Nonstatutory Stock Options (as defined in the Plan) to the extent required by law. 
 (iv) COBRA Coverage. Subject to
your timely conversion election, the Company will pay the premiums for your COBRA coverage at the rates then in effect for active employees (subject to any subsequent changes in the rates that are generally applicable to the Company’s active
employees) until the earlier of the sixth month anniversary of your Separation Date or the date you become covered under another employer’s group health plan (“COBRA Subsidy”). 

(v) Retention of Company Laptop and Blackberry. The Company will allow you to keep the laptop computer and Blackberry smart phone
issued to you during your employment. 
 Except for the separation terms proposed in this letter, you will not be entitled to any compensation,
benefits or other perquisites of employment after your last day of employment. You agree that the Company’s provision of separation benefits to you shall not be deemed as an admission of liability by the Company. 

In exchange for the separation benefits described above, you agree that you and your representatives waive all claims
of any kind, known and unknown, which you may now have or have ever had against Zeltiq Aesthetics, Inc., its affiliated, related, parent and subsidiary corporations, and its and their present and former directors, officers, and employees. This
release includes all claims arising from your employment with the Company and its termination, including employment discrimination claims under the California Fair Employment and Housing Act, Title VII, the Age Discrimination in Employment Act
(“ADEA”), and any other state or federal law1. You also agree not to initiate or cause to
be initiated any lawsuit, investigation or proceeding of any kind concerning the claims released by this paragraph, or to voluntarily participate in one except as required by law. Notwithstanding the foregoing, you acknowledge and agree that you are
not waiving or being required to waive any right or claim that cannot be waived as a matter of law. 
 You understand and agree
that this letter shall be maintained in strict confidence, and that you shall not disclose any of its terms to another person, except legal counsel, unless required by law. You further agree not to disparage Zeltiq Aesthetics, Inc. or any of its
affiliates, including their business reputations or business relationships. 
 You agree to return all the Company’s
materials in your possession, except the laptop computer and Blackberry discussed above, as soon as possible. You also agree to 

 

	1 	 Because this release specifically covers known and unknown claims, you are waiving your rights under Section 1542 of the California Civil Code or
any comparable law of any other jurisdiction. Section 1542 states: “A general release does not extend to claims which the creditor does not know or suspect to exist in his or her favor at the time of executing the release, which if known
by him or her must have materially affected his or her settlement to the debtor.” 

 
sign and return the Termination Certificate to the Employee Proprietary Information and Inventions Agreement you entered into during your employment, and understand that even after your
employment with the Company ends, you must comply with your continuing obligations under that Agreement, including your obligation to maintain the confidentiality of the Company’s confidential and proprietary information. 

This letter agreement, the Employee Proprietary Information and Inventions Agreement contain all of our agreements and understandings and
fully supersede any prior agreements or understandings that we may have had regarding your employment with the Company or its termination. Notwithstanding the foregoing, you understand that the Company’s 2005 Stock Option Plan and the
December 11, 2007 Restricted Stock Option Agreements and related promissory notes (as amended by your Employment Agreement) between you and the Company remain in full force and effect. 

This agreement shall be governed by California law and may be amended only in a written document signed by you and the Company’s
President. If any term in this agreement is unenforceable, the remainder of the agreement will remain enforceable. This agreement shall be binding upon and shall inure to the benefit of the parties and their respective heirs, successors, attorneys
and permitted assigns. You agree, however, that you will not assign any rights or obligations under this agreement, and any such purported assignment shall be null and void. 
 You agree that you have been advised that you have 21 days to consider this agreement (but may sign it at any time beforehand if you so desire). You also acknowledge that you have been advised to consult
an attorney in considering this agreement. You also understand that you can revoke this agreement within 7 days of signing it by sending a certified letter to that effect to me. Notwithstanding the foregoing, you understand and agree that the
portion of this agreement that pertains to the release of claims under the ADEA shall not become effective or enforceable and no funds shall be exchanged until the 7-day revocation period has expired, but that all other provisions of this agreement
will become effective upon its execution by the parties. 

 If you have any questions, please feel free to call me. Please do not sign this agreement
before December 3, 2010. We wish you the very best in your future endeavors. 
  

					
		 		 	Very truly yours,
			
	 	 		 	/s/ Gordie Nye
		 		 	Gordie Nye
		 		 	Chief Executive Officer

 To accept the severance package described above, please sign below and return this letter to me on or
before December 24, 2010. 
  

					
	AGREED:	 		 	
			
	Dated: 12/17/10	 		 	/s/ Mitch Levinson
		 		 	Mitch Levinson

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