Document:

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                                                                   EXHIBIT 10.22

                        Citadel Broadcasting Corporation
                       7201 W. Lake Mead Blvd., Suite 400
                               Las Vegas, NV 89128

                                                                   July 17, 2003

Mr. Farid Suleman
Greenwich, CT

Dear Farid:

This letter is intended to clarify the letter, dated February 15, 2002,
describing the terms of your employment with Citadel Broadcasting Corporation.
This letter confirms our mutual understanding that your annual bonus, described
in the letter under the heading "Compensation", may be paid either in cash or in
the form of warrants, at the option of Citadel's board of directors. This letter
also confirms that, if the annual bonus is paid in the form of warrants, the
exercise price and number of shares to which the warrants relate will be
determined by Citadel's board of directors on the date of payment, so that the
value of the warrants (as determined by the board of directors) is equal to the
amount of the bonus awarded by the board of directors.

If the above comports with your understanding of our agreement, please sign
below and return one copy to me and retain one copy for your records.

Very truly yours,

CITADEL BROADCASTING CORPORATION

By: /s/ Sandra J. Horbach
   -----------------------
Name:  Sandra J. Horbach
Title: Vice President and Assistant Secretary

/s/ Farid Suleman
-----------------------
Farid Suleman<Page>

                                                                    Exhibit 10.7

                           NEW COLLABORATION AGREEMENT

     This NEW COLLABORATION AGREEMENT (the "Agreement"), effective as of January
1, 2003 (the "Effective Date"), is made by and between Fuso Pharmaceutical
Industries, Ltd., a corporation organized under the laws of Japan, with a
principal place of business at 3-11, 2-Chome, Morinomiya, Joto-ku Osaka 536-8523
Japan and its registered head office at 7-10, 1-Chome, Doshomachi, Chuo-ku,
Osaka 541-0045 Japan ("Fuso"), and GenVec, Inc., a Delaware corporation, with a
principal place of business at 65 West Watkins Mill Road, Gaithersburg, Maryland
20878 ("GenVec").

                                   BACKGROUND

     A.      GenVec has expertise in the field of gene therapy and is developing
novel, proprietary materials and methods for use in the treatment of human
cancer.

     B.      Fuso is in the business of developing, manufacturing, and
commercializing pharmaceuticals in Japan.

     C.      GenVec and Fuso established a collaborative relationship on
September 26, 1997 to conduct research and develop certain gene therapy products
for the treatment of human cancer.

     D.      GenVec and Fuso desire to extend such collaboration under the terms
and conditions of this Agreement.

     NOW THEREFORE, for and in consideration of the covenants, conditions, and
undertakings hereinafter set forth, it is agreed by and between the parties as
follows:

1.   DEFINITIONS

     1.1     "AFFILIATE" shall mean any corporation or other entity which is
directly or indirectly controlling, controlled by or under the common control of
a party hereto. For the purpose of this Agreement, "control" shall mean the
direct or indirect ownership of at least fifty percent (50%) of the outstanding
shares or other voting rights of the subject entity to elect directors, or if
not meeting the preceding, any entity owned or controlled by or owning or
controlling at the maximum control or ownership right permitted in the country
where such entity exists.

     1.2     "AGREEMENT TERM" shall have the meaning set forth in Section 11.1.

[*]-CERTAIN INFORMATION IN THIS EXHIBIT HAS BEEN OMITTED AND FILED SEPARATELY
WITH THE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN REQUESTED WITH RESPECT TO
THE OMITTED PORTIONS. OMITTED TEXT IS INDICATED BY A "*".

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     1.3     "BIOLOGICAL LICENSE APPLICATION" or "BLA" shall mean the Japanese
equivalent of a Biological License Application, as defined in the U.S. Food,
Drug and Cosmetic Act and the regulations promulgated thereunder, and any
corresponding foreign application, registration or certification in the
Territory.

     1.4     "* VECTOR" shall mean either a * Vector or a * Vector, in either
case that incorporates the nucleic acid sequence for * and does not incorporate
any other nucleic acid sequence encoding a protein intended for or otherwise
conferring therapeutic benefit.

     1.5     "COLLABORATION PRODUCT" shall mean a *-TNF Vector developed in the
Research Program intended for use in the Field which the Steering Committee has
designated as such pursuant to Section 2.4. In addition, pursuant to Section
2.4.1, a * Vector also may be treated as a Collaboration Product.

     1.6     "COMMERCIALIZATION AGREEMENT" shall mean that certain New
Commercialization Agreement entered by Fuso and GenVec of even date herewith.

     1.7     "CONFIDENTIAL INFORMATION" shall mean (i) any proprietary or
confidential information or material in tangible form disclosed hereunder that
is marked as "Confidential" at the time it is delivered to the receiving party,
(ii) proprietary or confidential information disclosed orally hereunder which is
identified as confidential or proprietary when disclosed and such disclosure of
confidential information is confirmed in writing within thirty (30) days by the
disclosing party, or (iii) was Confidential Information under that certain
Collaboration Agreement between the parties dated September 26, 1997 as that
term was defined therein.

     1.8     "* VECTOR" shall mean a replication-deficient adenovector that: (i)
has been *.

     1.9     "*-TNF VECTOR" shall mean a * Vector that incorporates the nucleic
acid sequence encoding TNFalpha and does not incorporate any other nucleic acid
sequence encoding a protein intended for or otherwise conferring therapeutic
benefit.

     1.10    "DEVELOPMENT PLAN" shall mean the written plan for development of a
particular Collaboration Product prepared pursuant to Section 2.4.2.

     1.11    "FIELD" shall mean Gene Therapy for the treatment of human
cancer, *.

     1.12    "FUNDED RESEARCH TERM" shall have the meaning set forth in Section
2.6.1.

     1.13    "FUSO TECHNOLOGY" shall mean Fuso Patent Rights and Fuso Know-How:

             1.13.1 "FUSO PATENT RIGHTS" shall mean (i) all patents and patent
applications conceived and reduced to practice by Fuso alone, or Fuso and/or its
agents, in connection with this Agreement or the Commercialization Agreement or
in connection with the Past Research Program, and (ii) any divisions,
continuations, continuations-in-part, reissues, reexaminations, extensions or
other governmental actions which extend any of the subject matter of the patent
applications or patents in (i) above, and any substitutions, confirmations,
registrations or revalidations of any of the foregoing, in each case, which are
owned or controlled, in whole or

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part, by license, assignment or otherwise by Fuso, to the extent Fuso has the
right to license or sublicense, and subject to any limitations of (a) such
license, assignment or other grant to Fuso, and (b) any license or sublicense
(x) granted by Fuso at any time to any other entity or entities in the
settlement of patent-related disputes (e.g., an actual or potential patent
interference or opposition, or patent infringement suit) or (y) otherwise
materially relevant to Fuso's business. For the avoidance of doubt, the Fuso
Patent Rights shall not include Fuso Know-How or any Gene Therapy Technology.

             1.13.2 "FUSO KNOW-HOW" shall mean confidential information and
materials, including, but not limited to, pharmaceutical, chemical, biological
and biochemical products, technical and non-technical data, and information
relating to the results of tests, assays, methods and processes, and drawings,
plans, diagrams, specifications and/or other documents containing said
information and data, discovered, developed or acquired by Fuso alone, or Fuso
and/or its agents, in connection with this Agreement or the Commercialization
Agreement or in connection with the Past Research Program which Fuso has the
right to license or sublicense, and subject to any limitations of (a) such
license, assignment or other grant to Fuso, and (b) any license or sublicense
(x) granted by Fuso at any time to any other entity or entities in the
settlement of patent-related disputes (e.g., an actual or potential patent
interference or opposition, or patent infringement suit) or (y) otherwise
materially relevant to Fuso's business. For the avoidance of doubt, Fuso
Know-How shall not include any Fuso Patent Rights or any Gene Therapy
Technology.

     1.14    "GENE THERAPY" shall mean the introduction of a nucleic acid
sequence encoding a protein intended for or otherwise conferring therapeutic
benefit into a person for therapeutic purposes (i) by in vivo introduction for
incorporation into cells of such person, or (ii) by ex vivo introduction into
cells for transfer into a person.

     1.15    "GENE THERAPY TECHNOLOGY" shall have the meaning set forth in
Section 7.1.2 below.

     1.16    "GENVEC TECHNOLOGY" shall mean GenVec Patent Rights, GenVec
Know-How and Gene Therapy Technology:

             1.16.1 "GENVEC PATENT RIGHTS" shall mean (i) all patents and patent
applications listed on Exhibit A hereto, or conceived and reduced to practice by
GenVec alone, or GenVec and/or its agents, in connection with this Agreement or
the Commercialization Agreement or in connection with the Past Research Program,
and (ii) any divisions, continuations, continuations-in-part, reissues,
reexaminations, extensions or other governmental actions which extend any of the
subject matter of the patent applications or patents in (i) above, and any
substitutions, confirmations, registrations or revalidations of any of the
foregoing, in each case, which are owned or controlled, in whole or part, by
license, assignment or otherwise by GenVec, to the extent GenVec has the right
to license or sublicense, and subject to any limitations of (a) such license,
assignment or other grant to GenVec, and (b) any license or sublicense (x)
granted by GenVec at any time to any other entity or entities in the settlement
of patent-related disputes (e.g., an actual or potential patent interference or
opposition, or patent infringement suit) or (y) otherwise materially relevant to
GenVec's business. For the avoidance of doubt, the GenVec Patent Rights shall
not include GenVec Know-How.

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             1.16.2 "GENVEC KNOW-HOW" shall mean confidential information and
materials, including, but not limited to, pharmaceutical, chemical, biological
and biochemical products, technical and non-technical data, and information
relating to the results of tests, assays, methods and processes, and drawings,
plans, diagrams, specifications and/or other documents containing said
information and data, discovered, developed or acquired by GenVec alone, or
GenVec and/or its agents, in connection with this Agreement or the
Commercialization Agreement or in connection with the Past Research Program,
which GenVec has the right to license or sublicense, and subject to any
limitations of (a) such license, assignment or other grant to GenVec, and (b)
any license or sublicense (x) granted by GenVec at any time to any other entity
or entities in the settlement of patent-related disputes (e.g., an actual or
potential patent interference or opposition, or patent infringement suit) or (y)
otherwise materially relevant to GenVec's business. For the avoidance of doubt,
GenVec Know-How shall not include any GenVec Patent Rights

     1.17    "* VECTOR" shall mean a replication-deficient adenovector that has
been *.

     1.18    "JOINT TECHNOLOGY" shall mean the Joint Patent Rights and Joint
Know-How.

             1.18.1 "JOINT PATENT RIGHTS" shall mean (i) all patents and patent
applications conceived and reduced to practice jointly by Fuso (and/or its
agents) and GenVec (and/or its agents), in connection with this Agreement or the
Commercialization Agreement or in connection with the Past Research Program and
(ii) any divisions, continuations, continuations-in-part, reissues,
reexaminations, extensions or other governmental actions which extend any of the
subject matter of the patent applications or patents in (i) above, and any
substitutions, confirmations, registrations or revalidations of any of the
foregoing. For the avoidance of doubt, the Joint Patent Rights shall not include
the Joint Know-How or any Gene Therapy Technology.

             1.18.2 "JOINT KNOW-HOW" shall mean confidential information and
materials, including, but not limited to, pharmaceutical, chemical, biological
and biochemical products, technical and non-technical data, and information
relating to the results of tests, assays, methods and processes, and drawings,
plans, diagrams, specifications and/or other documents containing said
information and data, discovered, developed or acquired jointly by Fuso (and/or
its agents), and GenVec (and/or its agents), in connection with this Agreement
or the Commercialization Agreement or in connection with the Past Research
Program. For the avoidance of doubt, the Joint Know-How shall not include the
Joint Patent Rights or any Gene Therapy Technology.

     1.19    "MHLW" shall mean the Japanese Ministry of Health, Labour and
Welfare, or any corresponding foreign registration or foreign regulatory
authority in the Territory.

     1.20    "PAST RESEARCH PROGRAM" shall mean the "Research Program" under
that certain Collaboration Agreement between the parties dated September 26,
1997 as that term is defined therein.

     1.21    "PHASE I", "PHASE II", and "PHASE III" shall mean Phase I (or Phase
I/II), Phase II (or Phase II/III), and Phase III clinical trials, respectively,
in each case as prescribed by the Japanese equivalent of applicable FDA IND
regulations, or any corresponding foreign statutes, rules or regulations in the
Territory.

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     1.22    "PIVOTAL TRIAL" shall mean a clinical trial that is designed to
provide data establishing the safety and efficacy of a Collaboration Product in
support of obtaining marketing approval from the MHLW.

     1.23    "PRODUCT CONFIGURATION" shall mean any potential product for use in
the Field containing a combination of one or more nucleic acid sequences
encoding a protein intended for or otherwise conferring therapeutic benefit and
other elements (e.g., a gene delivery vehicle and/or a gene expression
cassette).

     1.24    "RESEARCH PLAN" shall have the meaning set forth in Section 2.1.2
below.

     1.25    "RESEARCH PROGRAM" shall have the meaning set forth in Section 2.1
below. For the avoidance of doubt, the Research Program shall include activities
conducted pursuant to the Research Plan and activities conducted pursuant to any
Development Plan which the parties agree are to be included under the Research
Program.

     1.26    "STEERING COMMITTEE" shall have the meaning set forth in Section
2.2.1 below.

     1.27    "SUBLICENSEES" shall have the meaning given such term in the
Commercialization Agreement.

     1.28    "TERRITORY" shall mean Japan, Korea and Taiwan until, on a
Collaboration Product by Collaboration Product basis, the earlier of such time
as the option set forth in Section 5.2.1 of the Commercialization Agreement is
exercised by Fuso or expires, after which time with respect to each such
Collaboration Product, "Territory" shall have the meaning set forth in the
Commercialization Agreement for such Collaboration Product.

     1.29    "TNFERADE" shall mean an anti-cancer agent which (i) is the GV11
Vector incorporating a nucleic acid sequence encoding TNFalpha presently
known as TNFerade(TM) (Ad.egr.TNF.11D) or (ii) comprises another replication
deficient adenovector, that is not a * Vector, and the nucleic acid sequence
encoding TNFalpha and is under development or being commercialized at any
time during the Agreement Term by GenVec and/or its other collaborators as an
alternative to TNFerade(TM).

2.   RESEARCH PROGRAM

     2.1     RESEARCH PROGRAM.

             2.1.1  COLLABORATIVE EFFORT. Subject to the terms and conditions
set forth herein Fuso and GenVec will diligently conduct mutually agreed
collaborative research during the Funded Research Term in the Field pursuant to
a Research Plan with the primary objective of identifying and commencing the
development of at least one (1) Collaboration Product (the "Research Program").
The activities conducted in connection with the Research Program will be
overseen and administered by the Steering Committee pursuant to Section 2.2
below. Fuso and GenVec shall each use reasonable efforts to conduct the Research
Program in accordance with the Research Plan within the time schedules
contemplated therein.

             2.1.2  RESEARCH PLAN. Annually during the Funded Research Term, the
Steering Committee will prepare and agree upon a written plan (the "Research
Plan") that will (i) include a general overview and timetable for each party's
research activities and appropriate resources

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and budgets for such research during the next year of the Funded Research Term,
and (ii) set specific objectives for each year of the Funded Research Term,
which objectives will be updated or amended, as appropriate, by the Steering
Committee as research progresses. The initial Research Plan shall be agreed in
writing by the parties within * of the Effective Date. The Steering Committee
shall review the Research Plan on an ongoing basis and may make changes to the
Research Plan then in effect.

             2.1.3  DEVELOPMENT PLAN ACTIVITIES. The Research Program shall
include those activities, within the scope of a Development Plan agreed to by
the parties pursuant to Section 2.4.2, that the parties have agreed to conduct
in connection with the Research Program.

             2.1.4  SPONSORED ACADEMIC RESEARCH. Each party upon the approval of
the Steering Committee may from time to time engage academic researchers to
perform research for the Research Program pursuant to a sponsored research
agreement with an academic institution. It is understood and agreed that the
parties shall endeavor to negotiate and include in any such academic sponsored
research agreement relating to the Research Program provisions fully consistent
with those in this Agreement, including without limitation, policies related to
confidentiality and the filing of patent applications and enforcement of
patents. To the extent the provisions of any agreement negotiated between any
academic institution and GenVec, or Fuso, as the case may be, in connection with
any aspect of the Research Program are inconsistent with the terms and
conditions of this Agreement, the party wishing to enter such agreement shall
notify the Steering Committee prior to the execution of such agreement, and
provide an explanation of the reason for such inconsistency. The Steering
Committee shall have the authority to approve or disapprove such agreement, and
the parties hereto shall not enter into such agreement without the prior written
consent of the Steering Committee.

     2.2     STEERING COMMITTEE.

             2.2.1  RESPONSIBILITIES. Fuso and GenVec will establish a committee
to oversee, review and coordinate the Research Program and other activities
contemplated hereunder during the Agreement Term (the "Steering Committee"). The
Steering Committee shall be responsible for (i) establishing the Research Plan,
(ii) designating Collaboration Products for commercial development; (iii)
monitoring and reporting research progress and ensuring open and frequent
exchange between the parties with respect to Research Program activities, (iv)
determining whether to acquire licenses from third parties with respect to
intellectual property necessary or useful for the conduct of the Research
Program, and (v) discussing patent matters relating to Collaboration Products.

             2.2.2  MEMBERSHIP. The Steering Committee shall be comprised of six
(6) representatives. Three (3) members shall be appointed by Fuso, and three (3)
members shall be appointed by GenVec. Fuso and GenVec may each replace its
Steering Committee representatives at any time, with written notice to the other
party. From time to time, the Steering Committee may establish subcommittees to
oversee particular projects or activities, such as decisions regarding patent
matters.

             2.2.3  MEETINGS. The Steering Committee will meet at least four (4)
times per year at locations and times to be determined by the Steering
Committee. Members of the Steering Committee may participate in and vote at
meetings, in person by telephone or by video

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conference and may vote at meetings by proxy. The Steering Committee shall
prepare written minutes of each meeting and a written record of all Steering
Committee decisions, whether made at a Steering Committee meeting or otherwise.

             2.2.4  DECISION MAKING. All decisions of the Steering Committee
will be made by majority approval; provided, the designation of each
Collaboration Product as described in Section 2.4.1, the Development Plan for
each Collaboration Product as described in Section 2.4.2, and the approval of
research plans and proposals under Section 2.4.6, shall require unanimous
approval of the Steering Committee, and, if there is not unanimity with respect
to such a decision, such matter shall not be subject to arbitration. In the
event that a majority is not achieved within the Steering Committee for any
decision which does not require a unanimous vote, the dispute will be referred
to Fuso's President and GenVec's President, who shall meet promptly in person or
by telephone and endeavor to reach agreement. If such persons are unable to
resolve any disputes the parties shall settle such dispute as set forth in
Article 12 below.

     2.3     RESEARCH PROGRAM FUNDING.

             2.3.1  PAYMENTS.

                    (a)  Fuso shall pay to GenVec one million five-hundred
thousand dollars ($1,500,000) per year for the Research Program. Such amounts
shall be used by GenVec for its direct and indirect costs incurred in connection
with Research Program activities approved by the Steering Committee, including,
without limitation, research and development activities by GenVec, the supply by
GenVec (subject to Section 6.2 below) of Collaboration Products for the conduct
of clinical trials (including clinical trials in Japan) pursuant to the
applicable Development Plan, the preparation and transfer of documents in
support of clinical trials of Collaboration Products in Japan, patent
prosecution by GenVec, travel and management expenses related to the Research
Program, and general support of technology development by GenVec.

                    (b)  The parties anticipate that the amount of the funding
provided in Section 2.3.1(a) above will support the activities to be conducted
by GenVec in connection with the Research Program with the goal of identifying
and commencing the development of at least *. It is understood and agreed that
GenVec shall have no obligation to expend any amount on the Research Program
in excess of the amounts paid by Fuso to GenVec for the conduct of the
Research Program. GenVec shall use reasonable efforts to conduct the Research
Program activities approved by the Steering Committee in a cost efficient
manner consistent with the Research Program budget and GenVec's customary
practices.

             2.3.2  THIRD PARTY TECHNOLOGY.

                    (a)  In the event that GenVec acquires any rights to
intellectual property or technology for its general corporate research and
development activities which are useful for the Research Program, GenVec shall
pay any costs attributable to the general use of the same; provided, GenVec
shall have no obligation to acquire with respect to any such intellectual
property or technology (i) the right to sublicense to Fuso any such intellectual
property or technology, or (ii) any rights relating to the commercialization of
Collaboration Products or any other products.

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                    (b)  In the event that it is necessary for GenVec to acquire
a license or GenVec has acquired a license from a third party specifically for
intellectual property or technology necessary or useful for the conduct of the
Research Program and/or the commercialization of Collaboration Products, GenVec
and Fuso shall negotiate and agree on the amounts that each party will be
responsible for paying to such third party with regard to such a license, and
for the expenses of negotiating and preparing any such license. In the event
that the parties are unable to agree on such amounts, GenVec shall have no
obligation to acquire such license and shall have no liability under this
Agreement for not acquiring such a license. It is understood and agreed that
GenVec shall have the principal responsibility for negotiating such agreements
unless otherwise agreed by the parties. In negotiating such agreements, GenVec
shall use reasonable efforts to reach an agreement which is as favorable as
possible to both GenVec and Fuso. GenVec shall report to Fuso on the progress of
such negotiations on a timely basis.

             2.4    COLLABORATION PRODUCTS.

             2.4.1  DESIGNATION. During the Funded Research Term, either party
shall have the right to nominate for further development as a Collaboration
Product any *-TNF Vector previously studied or currently under study in the
Research Program. GenVec shall not have the right to prevent Fuso from
developing a Collaboration Product for systemic and regional delivery
applications for the reason that TNFerade may be suitable and pursued for
similar regional or systemic applications. Further, GenVec shall not have the
right to prevent Fuso from developing a Collaboration Product that is a *-TNF
Vector for local delivery applications in case that the development of a *-TNF
Vector for regional or systemic application proves not to be feasible, (provided
such Collaboration Product is suitable for the proposed local delivery
applications), unless: (i) a * Vector or a Product Configuration other than a
*-TNF Vector is or becomes designated a Collaboration Product or (ii) GenVec
offers to pay Fuso *% of the net revenues received by GenVec from sales of
TNFerade in the Territory until the earlier of (a) the date Fuso receives such
payments equal to the total payments Fuso has made to GenVec under Section
2.3.1(a) specifically for the research and development of *-TNF Vector(s) or (b)
* after the end of the Funded Research Term.

             In addition, provided Fuso has initiated, or is diligently pursuing
the initiation of Phase I clinical trials of the * Vector *, Fuso shall either
nominate such Product Configuration as a Collaboration Product or cease
continued activities with respect to such Product Configuration prior to the end
of the Funded Research Term. At the next Steering Committee meeting after such
nomination, or such later time as the parties may agree, the Steering Committee
shall vote whether or not to designate such *-TNF Vector or * Vector as a
Collaboration Product. Any Product Configuration which is unanimously approved
as a Collaboration Product shall be a Collaboration Product for all purposes of
this Agreement. Product Configurations which are not designated as Collaboration
Products as set forth above shall not be Collaboration Products.

             2.4.2  DEVELOPMENT PLAN. Concurrent with the designation of any
Product Configuration as a Collaboration Product, the Steering Committee shall
unanimously agree on a comprehensive written development plan for the Territory
for such Collaboration Product through the completion of clinical trials in
Japan (the "Development Plan"), which shall include specific activities, tasks
and timelines for Fuso (and if applicable GenVec) reasonable to accomplish the
foregoing, and reasonable budgets for such activities sufficient to accomplish
the foregoing, an

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assessment of relevant business considerations (including, without limitation,
competitive activities of third parties, any patent rights of third parties and
the likelihood that commercially valuable patent rights could be obtained for
such a Collaboration Product), and principles regarding the coordination of such
activities with the development and commercialization by GenVec and its
Affiliates, other collaborators and licensees of Collaboration Products outside
the Territory consistent with Section 2.4.6. All or some of such activities may
be conducted in connection with the Research Program, as agreed by the Steering
Committee. For any Development Plan activities which are to be conducted in
connection with the Research Program or which otherwise involve GenVec, subject
to Section 5.1, the Steering Committee shall agree on the financial obligations
of each party with respect to costs incurred in implementing such Development
Plan activities.

             2.4.3  NO AGREEMENT. In the event that the Steering Committee fails
to agree to designate as a Collaboration Product a particular Product
Configuration that Fuso (i) nominated, (ii) prepared a Development Plan for
meeting the criteria in Section 2.4.2 above, and (iii) supported as a
Collaboration Product by voting for the applicable Development Plan, then GenVec
may not independently develop or commercialize such Product Configuration in the
Territory for the Field until after the Agreement Term, unless GenVec has,
subject to Section 2.4.4, previously commenced or established its intent to
commence research (as shown by written records) with respect to such a Product
Configuration, alone or with a third party, prior to the date Fuso proposed to
the Steering Committee that such Product Configuration be designated as a
Collaboration Product.

             2.4.4  INDEPENDENT DEVELOPMENT. Subject to Section 2.4.5, Fuso and
GenVec shall each have the right to conduct research relating to the Field
independently or with third parties.

             2.4.5  NON-COMPETE.

                    (a)  Fuso shall not, directly or indirectly, develop or
commercialize, or enter into any collaboration agreement or other agreement with
any third party for the manufacture, development or commercialization, of any
product comprising a nucleic acid sequence encoding TNF or * or a modification
or derivative thereof during the period beginning on the Effective Date and
ending the later of * after the end of the Agreement Term or the termination or
expiration of the Commercialization Agreement, other than a Collaboration
Product developed and commercialized pursuant to this Agreement and the
Commercialization Agreement.

                    (b)  GenVec shall not in the Field in the Territory,
directly or indirectly, develop or commercialize, or enter into any
collaboration agreement or other agreement with any third party for the
manufacture, development or commercialization of: (i) any product that is
exactly the same as a Collaboration Product during the Agreement Term and the
term of the Commercialization Agreement, (ii) any product that is a * Vector
that incorporates a nucleic acid sequence encoding TNFalpha or * or is a *
Vector that incorporates a nucleic acid sequence encoding * during the period
beginning on the Effective Date and ending the earlier of the expiration or
termination of this Agreement or December 31, 2005 or, in the case of a product
that incorporates a nucleic acid sequence encoding *, the earlier of such dates
and the date Fuso ceases activities with respect to the * Vector currently under
investigation by

                                       -9-
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Fuso as a potential Collaboration Product, (iii) any product that is a * Vector
that incorporates a nucleic acid sequence encoding TNFalpha, or is a version of
TNFerade that is engineered for regional/systemic application(s), with respect
to the same indication(s) for which a Collaboration Product that incorporates a
nucleic acid sequence encoding TNFalpha is being developed and commercialized in
the Field in the Territory during the period beginning on the Effective Date and
ending on the expiration or termination of the Commercialization Agreement,
unless the Steering Committee after December 31, 2005 determines that such
product *, and (iv) any product that is a * Vector that incorporates a nucleic
acid sequence encoding * or is a * Vector that incorporates a nucleic acid
sequence encoding *, with respect to the same indication(s) for which a
Collaboration Product that incorporates a nucleic acid sequence encoding * is
being developed and commercialized in the Field in the Territory during the
period beginning on the Effective Date and ending on the expiration or
termination of the Commercialization Agreement, unless the Steering Committee
after December 31, 2005 determines that such product has significant medical
(e.g., efficacy or safety) or commercial advantages over such Collaboration
Product; in each case other than a Collaboration Product developed and
commercialized pursuant to this Agreement and the Commercialization Agreement.

             2.4.6  WORLDWIDE COORDINATION. In performing research and related
activities under the Research Program, GenVec shall comply with the applicable
cGLP, cGCP and cGMP practices of the countries in the Territory as to which it
has received written notice from Fuso setting forth such practices, except to
the extent such cGLP, cGCP and cGMP practices conflict with the cGLP, cGCP or
cGMP practices in countries other than the Territory. Additionally, to permit
alignment of the research objectives of the parties, avoid duplication of
effort, facilitate the exchange of information, avoid prejudice to products of
GenVec or its other licensees anywhere in the world and maximize the prospects
for success of the Research Program and the Collaboration Products, during the
Agreement Term, Fuso shall not undertake any research, development or testing
activities with respect to any Collaboration Product or any other Product
Configuration previously studied or currently under study in the Research
Program unless Fuso first provides the Steering Committee Fuso's plans and
protocols therefor, and any modifications thereto, and the same are approved by
the Steering Committee prior to the implementation thereof, with such approval
not to be unreasonable witheld.

     2.5     RECORDS; REPORTS OF INFORMATION.

             2.5.1  RECORDS. The parties shall maintain (i) financial records
until at least three (3) years after the date of their creation in sufficient
detail to establish how Research Program funds are expended, and (ii)
scientific records until at least three (3) years after the Agreement Term,
or longer as required by applicable law or regulations or requested by
regulatory authorities having jurisdiction thereof (provided Fuso provides
GenVec notifications of such requests prior to the end of the Agreement Term,
and for records relevant to any Fuso Patent Rights, GenVec Patent Rights or
Joint Patent Rights, until the end of the life of the relevant patent) that
will properly reflect all work done and results achieved in the performance
of the Research Program (including all data in the form required under any
applicable governmental regulations, including such data arising in
connection with clinical trials) in a manner sufficient to establish the
dates of first conception and reduction to practice of any inventions. Upon
request, the parties shall provide each other access to such records relating
to any Collaboration Product during ordinary business hours to make available
copies (including those in electronic forms) of such records to the extent

                                      -10-
<Page>

necessary in relation to BLA filing or other regulatory requirements during the
above-mentioned term.

             2.5.2  REPORTS. The Steering Committee shall periodically and not
less often than semiannually during the Agreement Term, request and the parties
shall have the obligation to prepare and provide to the Steering Committee
written reports summarizing the progress of the research performed by or
sponsored by the parties pursuant to the Research Plan during the preceding
half-year (including updates on the status of interference proceedings pending
in the U.S. Patent and Trademark Office, if applicable). In addition, during the
Funded Research Term, each party shall provide the other party with a quarterly
accounting report regarding Research Program expenditures by such party in the
preceding quarter.

     2.6     TERM AND TERMINATION OF RESEARCH PROGRAM.

             2.6.1  FUNDED RESEARCH TERM. The term of the Research Program shall
commence on the Effective Date and, unless terminated earlier pursuant to
Section 2.6.2 or Article 11, continue until December 31, 2005 (the "Funded
Research Term").

             2.6.2  TERMINATION. After the second anniversary of the Effective
Date Fuso may, with ninety (90) days prior written notice to GenVec, terminate
its support for research by GenVec in connection with the Research Program. In
such an event, the Research Program shall terminate and GenVec may continue, at
its own expense, any such research initiated in connection with the Research
Program. In any such event, subsequent activities undertaken by GenVec shall not
be included in or be part of the Research Program, and notwithstanding any other
provision of this Agreement, any intellectual property developed in connection
with such independent GenVec activities shall not be included in the GenVec
Technology or the Joint Technology.

             2.6.3  LACK OF DILIGENCE. If GenVec is not diligent and Fuso
terminates the Research Program in accordance with Section 11.2, GenVec shall
return to Fuso (i) any amounts unexpended on the Research Program by GenVec due
to GenVec's lack of diligence, and (ii) any amounts which an arbitrator, in an
arbitration proceeding conducted pursuant to Article 12, deems were expended by
GenVec in the Research Program without acting in a diligent manner
("Non-Diligent Research"). Notwithstanding the above, any amounts that GenVec
has provided to a third party with the approval of the Steering Committee to
sponsor research related to the Research Program which an arbitrator deems
Non-Diligent Research shall be returned to Fuso by GenVec only to the extent
that GenVec is able to obtain a refund from such third party.

     2.7     PUBLICATION.

             2.7.1  REVIEW. As soon as is practicable prior to the oral public
disclosure and prior to the submission to any outside person for publication of
a manuscript describing the scientific data resulting from any stage of the
Research Program, the authors of such disclosure shall disclose to the Steering
Committee the disclosure or manuscript to be made or submitted, and shall allow
the Steering Committee at least thirty (30) days to determine whether such
disclosure or manuscript contains subject matter for which patent protection
should be sought prior to publication or which the other believes should be
modified or deleted to avoid regulatory or commercial difficulties. With respect
to publications by investigators or other third parties,

                                      -11-
<Page>

such publications shall be subject to majority review by the Steering Committee
under this Section 2.7 to the extent that Fuso or GenVec (as the case may be)
has the right to do so.

             2.7.2  DELAY OF PUBLICATION. Prior to the expiration of the thirty
(30) day period specified in Section 2.7.1, the Steering Committee may notify
the submitting party of its determination that such oral presentation or
manuscript contains objectionable material or material that consists of
patentable subject matter for which patent protection should be sought. The
notified party shall withhold its proposed public disclosure and confer with the
Steering Committee to determine the best course of action to take in order to
modify the disclosure or to obtain patent protection. After resolution of the
regulatory or commercial issues, or the filing of a patent application, the
submitting party shall be free to submit the manuscript and/or make its public
oral disclosure.

             2.7.3  PUBLICATION RIGHTS. After the expiration of thirty (30) days
from the date of mailing such disclosure or manuscript, unless Fuso or GenVec
has received from the other or the Steering Committee the written notice
specified above, the authoring party shall be free to submit such manuscript for
publication or to publish the disclosed research results. Any such publication
shall include an acknowledgment of the contributions of each party, subject to
customary scientific norms.

3.   LICENSE GRANTS

     3.1     RESEARCH LICENSES.

             3.1.1  LICENSES TO FUSO. Subject to the terms and conditions of
this Agreement, GenVec hereby grants to Fuso: (i) a * license under the Gene
Therapy Technology jointly developed by GenVec and Fuso * in the *; and (ii)
a * license under the GenVec Technology * as described in Article 5 in the *.

             3.1.2  SUBLICENSES. Fuso may sublicense the rights granted in
Section 3.1.1 to * only to the extent that such sublicenses are reasonably
necessary for Fuso to conduct research activities in connection with the
Research Program and clinical trials as described in Article 5.

     3.2     RETAINED RIGHTS. It is understood and agreed that GenVec shall
retain the exclusive right to (i) make, have made, use, sell and otherwise
commercialize the Collaboration Products for all uses within the Field outside
the Territory; (ii) subject to Section 2.4.5, to make, have made, use, sell and
otherwise commercialize the Collaboration Products for use outside the Field,
both in and outside the Territory; (iii) to make, have made, use and sell
Collaboration Products to Fuso in connection with the activities conducted by
GenVec pursuant to this Agreement, unless and until Fuso assumes manufacture of
the Collaboration Products, and (iv) to practice any method, process or
procedure within, and otherwise develop, exploit and/or commercialize the Gene
Therapy Technology.

     3.3     NO IMPLIED LICENSES. No rights or licenses with respect to the
GenVec Technology or the Fuso Technology or other intellectual property owned by
GenVec or Fuso are granted or shall be deemed granted hereunder or in connection
herewith, other than those rights expressly granted in this Agreement.

                                      -12-
<Page>

     3.4     FUSO INDEPENDENT TECHNOLOGY. If during the Agreement Term Fuso owns
or controls intellectual property or materials not within the Fuso Technology
(as defined in Section 1.13) which may be useful for the conduct of the Research
Program or the development or commercialization of Collaboration Products, Fuso
may notify the Steering Committee identifying such intellectual property and
materials, and in such event the parties shall negotiate in good faith the terms
on which Fuso would make available such intellectual property and materials for
the Research Program and/or the development or commercialization of
Collaboration Products. Such terms shall include the terms relating to the
ownership of such Fuso independent technology and improvements thereto, and
shall govern in the event of any conflict between such terms and the terms of
this Agreement. If the parties do not enter into a further written agreement,
Fuso shall have no obligation to make such intellectual property or materials
available to GenVec for any purpose.

4.   PAYMENTS

     4.1     RESEARCH PROGRAM FUNDING. Fuso shall pay to GenVec funding for the
Research Program of one million five hundred thousand dollars ($1,500,000) each
calendar year during the Funded Research Term. Such amounts shall be paid to
GenVec in equal quarterly installments of three hundred seventy five thousand
dollars ($375,000), in advance. The initial payment shall be paid by January 1,
2003, and subsequent payments shall be made on or before the first day of each
succeeding calendar quarter (i.e., April 1, July 1, October 1, January 1). Such
payments shall be made without withholding for taxes or any other charge and,
subject to Section 2.6.3, shall be non-refundable.

     4.2     MILESTONE COST REIMBURSEMENT. Within * after the first occurrence
in Japan of each of the events specified below with respect to each
Collaboration Product, Fuso shall pay to GenVec the following amounts:

<Table>
<Caption>
           MILESTONES                            AMOUNT
           ----------                            ------
           <S>                                <C>
           *                                   $     *
           *                                   $     *
           Total                               $1,500,000
</Table>

Fuso shall promptly notify GenVec upon the achievement of each of the foregoing
milestones with respect to each Collaboration Product. It is understood that
such payments shall be made to share the costs incurred by GenVec in connection
with any research, pre-clinical studies and/or clinical trials in the United
States for such Collaboration Product in consideration for the right to receive
data relating to such research, pre-clinical studies and/or clinical trials from
GenVec pursuant to Section 5.1.1.

     4.3     WITHHOLDING TAXES. All payments required to be made to GenVec
pursuant to Article 4 shall be without deduction or withholding for or on
account of any taxes or similar governmental charge.

     4.4     TAXES. Any transfer taxes, import duties and other taxes or
governmental charges required to be paid in connection with the transfer to Fuso
of any Collaboration Products manufactured by GenVec hereunder shall be the sole
responsibility of Fuso. In the event that

                                      -13-
<Page>

GenVec is required to pay any such amounts. Fuso shall promptly remit payment to
GenVec of such amounts.

5.   CLINICAL TRIALS

     5.1     COLLABORATION PRODUCT DEVELOPMENT BY FUSO.

             5.1.1  COLLABORATION PRODUCTS DEVELOPED BY GENVEC. It is understood
by the parties that the data to be obtained as the result of clinical trials
conducted by GenVec in the United States are useful to get the authorization
of commencement of Phase I clinical studies in Japan from the Ministry of
Education, Culture, Sports, Science and Technology and MHLW. GenVec agrees to
first commence clinical trials in the United States for each collaboration
product that the Steering Committee agrees should be studied first in the
United States, and to provide * in a timely manner. Notwithstanding the
foregoing, the Steering Committee shall have no obligation to agree such
studies should be first conducted in the United States. However, GenVec shall
have no right to * that is required by * for * of such Collaboration Product
unless GenVec, or a third party authorized by GenVec, first *.

             5.1.2  COLLABORATION PRODUCT DEVELOPMENT BY FUSO. Except as
expressly provided otherwise in this Agreement, Fuso shall be responsible for
all costs of conducting development of Collaboration Product(s) in the Territory
in accordance with the applicable Development Plan(s), including, without
limitation expenses incurred *. During the Agreement Term, Fuso shall keep
GenVec fully informed of its activities subject to this Agreement, including
without limitation the achievement of the milestones set forth in Section 4.2
and, in addition, on or before January 31 of each year, Fuso shall provide
GenVec with a written report detailing such events and activities.

     5.2     DUE DILIGENCE.

             5.2.1  REASONABLE EFFORTS. Fuso shall use all reasonable efforts
to: (i) promptly develop the Collaboration Products following designation of
such Collaboration Product, and (ii) achieve the milestones set forth in Section
5.2.2(a).

             5.2.2  MILESTONES.

                    (a)  ACHIEVEMENT BASED. Subject to Sections 5.2.2(b) and
5.2.3 below, if each of the following milestones are not timely met by Fuso or
its Sublicensees in Japan with respect to any Collaboration Product with respect
to the dates below (unless other dates are agreed by the Steering Committee and
specified in the applicable Development Plan) the license granted to Fuso with
respect to such Collaboration Product shall terminate in the Territory, and all
rights granted to Fuso relating to such Collaboration Product will revert to
GenVec.

*                                                    * from *.

*                                                    * from the date of *.

*                                                    * from *.

                                      -14-
<Page>

*                                                    * from *.

Fuso shall use all reasonable efforts to obtain the authorization of the
Ministry of Education, Culture, Sports, Science and Technology and MHLW for the
commencement of clinical studies concerning the applicable Collaboration Product
within the applicable * period prescribed above.

                    (b)  EXPENDITURE BASED. In the event that Fuso has failed to
satisfy any of the achievement-based diligence requirement described in Section
5.2.2(a) with respect to particular Collaboration Product, Fuso may establish
its diligence by demonstrating to GenVec that it has * in each of the previous
two (2) years. In such event, Fuso's license with respect to Collaboration
Product shall remain in effect for an additional period of *, provided that Fuso
continues to *. In the event Fuso * in such period, Fuso's license shall remain
in effect, subject to the terms of this Agreement. In such case, such *. The
parties shall reasonably agree on the annual expenditures described in the first
sentence of this Section 5.2.2(b) on or before * after the date the Steering
Committee designates a particular Collaboration Product pursuant to Section 2.4,
provided in the event the parties are unable to agree on such amount prior to
such date, or such later date as the parties agree, then the provisions of this
Section 5.2.2(b) shall not be effective with respect to such Collaboration.

             5.2.3  LACK OF DILIGENCE. In the event that Fuso fails to meet the
achievement-based or the expenditure-based diligence milestones with respect to
a particular Collaboration Product, GenVec may terminate this Agreement with
respect to such Collaboration Product pursuant to the provision of Section 11.2,
unless Fuso establishes that it has acted reasonably, diligently and in good
faith to meet the milestones but failed due to events outside Fuso's control,
which may include, but not limited to, difficulty to find patients and/or
doctors who are cooperative with the clinical trials or any change of the policy
of the MHLW or other authorities concerning general practice of clinical trials
and/or Gene Therapy. In such event, GenVec shall thereafter have the exclusive
rights to commercialize such Collaboration Products in the Territory, alone or
with third parties.

     5.3     REGULATORY FILINGS.

             5.3.1  RESEARCH PROGRAM-BASED. Each party and its Affiliates, and,
subject to such party's obligations to third parties, its licensees and
sublicensees, shall have the right, without charge, to refer to, access, cross
reference, and use documents relating to each Collaboration Product filed by a
party or its Affiliates or Sublicensees with regulatory entities with respect to
activities conducted in connection with the Research Program, including clinical
studies and other supporting information, and any written communications to and
with the MHLW, FDA and other comparable regulatory bodies.

             5.3.2  OUTSIDE THE RESEARCH PROGRAM. Subject to its obligations to
third parties, each party and its Affiliates, licensees and sublicensees shall
have the right to refer to, access, cross reference, and use documents filed
with regulatory entities relating to each Collaboration Product, filed by a
party or its Affiliates or Sublicensees in agreed jurisdictions, with respect to
activities conducted outside the Research Program, including clinical studies
and other supporting information, and any written communications to and with the
MHLW, FDA and other comparable regulatory bodies.

                                      -15-
<Page>

6.   *

     6.1     *.

             6.1.1  CLINICAL TRIALS IN THE U.S. GenVec shall have the first
right, but not the obligation to * clinical trials conducted outside the
Territory pursuant to the Research Plan or a Development Plan, on a
Collaboration Product-by-Collaboration Product basis. If GenVec elects not to
* such *, the parties shall agree whether Fuso or * shall * such *.

             6.1.2  CLINICAL TRIALS IN THE TERRITORY. Fuso shall have the
first right, but not the obligation to * in clinical trials in the Territory,
on a Collaboration Product-by-Collaboration Product basis, subject to
GenVec's approval not to be unreasonably withheld. GenVec's decision to
approve or disapprove * Fuso shall be based on Fuso's * and/or the period
Fuso may require to *. If Fuso elects not to * such *, or GenVec does not
approve of * of such * Fuso, GenVec shall have the first right, but not the
obligation, to * in clinical trials in the Territory, on a Collaboration
Product-by-Collaboration Product basis, subject to Fuso's approval, not to be
unreasonably withheld. Fuso's decision to approve or disapprove * GenVec
shall be based on GenVec's ability to * the *. In the event that GenVec
declines to * a particular *, or Fuso does not approve of the * of such * by
GenVec, then, subject to Section 6.2, Fuso may * reasonably acceptable to
GenVec, to * such *. GenVec and Fuso agree to reasonably cooperate to ensure
the availability of Collaboration Products for Phase I and Phase II clinical
studies in the Territory.

     6.2     *. If Fuso has * by a * pursuant to Section 6.1 above, it will
require that such * the * only to Fuso, its Affiliates or permitted
Sublicensees. In addition, (i) such * shall agree in writing to be bound by
the confidentiality obligations set forth in Article 9 hereof as if they were
a party to this Agreement, (ii) Fuso shall notify the name and financial
strength of each * to GenVec prior to the commencement of the *, and (iii)
Fuso shall remain responsible to GenVec for any failure by * to conform to
such obligation.

     6.3     PAYMENTS FOR *. During the Agreement Term, if GenVec * a
particular *, GenVec shall provide such * to Fuso for use in *, without
additional charge, if the cost of * such * is specifically provided for in
the applicable Research Plan and the Research Program funding paid to GenVec
pursuant to Section 2.3.1(b). In all other cases, Fuso shall pay to GenVec an
amount to be agreed by the parties for such *.

     6.4     TRANSFER OF *. If Fuso * pursuant to Section 6.1 above, the
parties shall negotiate in good faith the compensation to be paid to GenVec
for the * and *, and shall cooperate with each other in order that Fuso may
initiate * of the * as soon as practicable; provided, GenVec shall not be
obligated to transfer any * which is subject to a contractual obligation with
a third party.

     6.5     FUSO RESPONSIBILITIES. If Fuso undertakes to * the *, Fuso shall
be responsible for * associated therewith. All Collaboration Products * will
conform with all MHLW regulations and all applicable foreign laws and
regulations. Fuso shall keep GenVec fully informed of the * and developments
relating thereto and GenVec shall have the right on reasonable prior notice
to visit the * during ordinary business hours and review any relevant records
relating to * (excluding records relating to the * own proprietary *).

7.   INTELLECTUAL PROPERTY

     7.1     OWNERSHIP OF INVENTIONS.

             7.1.1  RESEARCH PROGRAM TECHNOLOGY. Subject to Section 7.1.2 below,
(i) title to all inventions and intellectual property made solely by GenVec
employees or its agents in

                                      -16-
<Page>

connection with the Research Program without inventive contribution by Fuso
employees or its agents shall be owned by GenVec; (ii) title to all inventions
and intellectual property made solely by Fuso employees or its agents in
connection with the Research Program without inventive contribution by GenVec
employees or its agents shall be owned by Fuso; and (iii) title to all
inventions and intellectual property made jointly by employees or the agents of
Fuso and GenVec in connection with the Research Program, shall be jointly owned
by GenVec and Fuso.

             7.1.2  GENE THERAPY TECHNOLOGY. Notwithstanding Section 7.1.1
above, GenVec shall own all inventions and intellectual property made in
connection with this Agreement during the Agreement Term (i) solely by GenVec
employees or agents or jointly by employees or agents of Fuso and GenVec that
relate to the introduction of genetic material of nucleic acid composition, or a
portion thereof, into a vector and/or cell to create a desired effect or
identify an unknown effect, including techniques and processes relating to the
manufacture, evaluation and use thereof, and methods relating to all of the
foregoing, (ii) by either or both of the parties and/or their agents that relate
to or are made using materials transferred to Fuso by or on behalf of GenVec, or
(iii) by either or both of the parties and/or their agents that relate to or are
made using Collaboration Products, * Vector, * Vector, *-TNF Vector or * Vector
(collectively, "Gene Therapy Technology"). Fuso hereby assigns to GenVec all its
right, title and interest it may otherwise hold in or to such Gene Therapy
Technology and any patent applications or patents relating thereto. Fuso shall,
at the request of GenVec, execute, and deliver or cause to be delivered, all
such consents, documents or further instruments of assignment or transfer, and
take or cause to be taken all such actions GenVec reasonably deems necessary or
desirable in order for GenVec to obtain the full benefits of the assignment
herein.

             7.1.3  INVENTORSHIP. Inventorship and rights of ownership of
inventions and other intellectual property rights conceived and/or reduced to
practice in connection with the Research Program shall be determined in
accordance with the patent and other intellectual property laws of the United
States or the State of Maryland, as applicable, as long as the laws of the
Territory permit application of such laws. Subject to the licenses granted in
Article 3, except as expressly provided in this Agreement, it is understood that
neither party shall have any obligation to account to the other for profits, or
to obtain any approval of the other party to license, permit sublicensing, or
exploit a Joint Technology for applications outside of the Field by reason of
joint ownership of any such intellectual property.

     7.2     PATENT PROSECUTION

             7.2.1  SOLE INVENTIONS. Fuso or GenVec, as the case may be, shall,
be responsible for preparing, filing, prosecuting and maintaining of the patent
applications and patents, solely owned by it, worldwide in such countries as it
deems appropriate, and conducting any interferences, reexaminations, reissues,
oppositions or requests for patent term extensions relating to the Fuso
Technology or GenVec Technology (respectively), using counsel of its choice, at
its expense; provided, such expenses may be included in the Research Program
funding described in Section 2.3.

             7.2.2  PATENT RIGHTS FOR JOINT TECHNOLOGY.

                    (a)  The parties will cooperate to file, prosecute and
maintain patent applications covering the Joint Technology(ies) in the United
States, European Union (in Europe

                                      -17-
<Page>

through a European Patent Convention application) and Japan (collectively, the
"Core Countries") and other countries agreed by the parties. The parties shall
agree which party shall be responsible for conducting such activities with
respect to a particular Joint Technology. The party conducting such activities
shall keep the other party fully informed as to the status of such patent
matters, including, without limitation, by providing the other party the
opportunity, at the other party's expense, to review and comment on any
documents relating to the Joint Technology which will be filed in any patent
office at least thirty (30) days before such filing, and promptly providing the
other party copies of any documents relating to Joint Technology which the party
conducting such activities receives from such patent offices, including notice
of all interferences, reissues, reexaminations, oppositions or requests for
patent term extensions. The parties will share equally all expenses and fees
associated with the filing, prosecution, issuance and maintenance of any patent
application and resulting patent for a Joint Technology in the Core Countries
and other agreed countries and such amounts shall be included within the
Research Program funding described in Section 2.3.

                    (b)  In the event that either party wishes to seek patent
protection with respect to any Joint Technology outside the Core Countries, it
shall notify the other party hereto. If both parties wish to seek patent
protection with respect to such Joint Technology in such country or countries,
activities shall be subject to Section 7.2.2(a) above. If only one party wishes
to seek patent protection with respect to such Joint Technology in such country
or countries, it may file, prosecute and maintain patent applications and
patents with respect thereto, at its own expense. In any such case, the party
declining to participate in such activities shall not grant any third party a
license under its interest in the applicable Joint Technology in the applicable
country or countries without the prior written consent of the other party, which
consent shall not be unreasonably withheld.

     7.3     ENFORCEMENT.

             7.3.1  SOLELY OWNED TECHNOLOGY. Subject to 7.3.2 below, in the
event that any GenVec Technology or Fuso Technology (in this Section, both
referred to as "Technology") necessary for use of a Collaboration Product is
infringed or misappropriated by a third party in any country in the Territory,
or is subject to a declaratory judgment action arising from such infringement in
such country, Fuso or GenVec, as the case may be, shall promptly notify the
other party hereto. The party which owns or controls such Technology (the
"Owner") shall have the initial right (but not the obligation) to enforce such
Technology, or defend any declaratory judgment action with respect thereto, at
its expense. In the event that the Owner fails to initiate a suit to enforce
such Technology against a commercially significant infringement in the Field by
a third party in any jurisdiction in the Territory within * of a request by the
other party (the "Licensee") to do so, Licensee may, subject to the Owner's
agreements with third parties, initiate such suit in the name of the Owner of
such Technology against such infringement, at the expense of such Licensee. The
party involved in any such claim, suit or proceeding, shall keep the other party
hereto reasonably informed of the progress of any such claim, suit or
proceeding. Any recovery by such party received as a result of any such claim,
suit or proceeding shall be used first to reimburse such party for all expenses
(including attorneys and professional fees) incurred in connection with such
claim, suit or proceeding and if the party initiating the suit was the owner of
the subject Technology, all of the remainder shall be retained by such owner,
and if the party initiating the suit is the Licensee, * percent (*%) of the
remainder shall be paid to the owner of the subject Technology and * percent
(*%) retained by the Licensee. If the Licensee

                                      -18-
<Page>

initiates such suit in the name of the Owner of such Technology against such
infringement, the Licensee shall not enter into any agreement which makes any
admission regarding (i) wrongdoing on the part the Owner, or (ii) the
invalidity, unenforceability or absence of infringement of the Owner's
Technology, without the prior written consent of the Owner, which consent shall
not be unreasonably withheld. The parties shall cooperate with each other in
connection with any such claim, suit or proceeding and shall keep each other
reasonably informed of all material developments in connection with any such
claim, suit or proceeding.

             7.3.2  JOINTLY OWNED TECHNOLOGY. Notwithstanding 7.3.1 above, in
the event that any technology that is jointly owned by GenVec and Fuso under
Section 7.1 of this Agreement is infringed or misappropriated by a third party,
Fuso and GenVec shall discuss whether, and, if so, how, to enforce such Joint
Technology or defend such Joint Technology in an infringement action,
declaratory judgment or other proceeding. In the event only one party wishes to
participate in such proceeding, it shall have the right to proceed alone, at its
expense, and may retain any recovery; provided, at the request and expense of
the participating party, the other party agrees to cooperate and join in any
proceedings in the event that a third party asserts that the co-owner of such
Joint Technology is necessary or indispensable to such proceedings.

     7.4     INFRINGEMENT CLAIMS. If the use of any Collaboration Product in
clinical trials in the Territory pursuant to this Agreement results in any
claim, suit or proceeding alleging patent infringement against GenVec or Fuso,
such party shall promptly notify the other party hereto. If Fuso is not named as
a party in such a claim, suit or proceeding, Fuso may, at its own expense and
through counsel of its own choice, seek leave to intervene in such claim, suit
or proceeding. GenVec agrees not to oppose such intervention. If Fuso, and not
GenVec, is named as a party to such claim, suit or proceeding, Fuso shall have
the right to control the defense and settlement of such claim, suit or
proceeding, at its own expense, using counsel of its own choice, however GenVec,
at its own expense and through counsel of its own choice, may seek to intervene
if the claim, suit or proceeding relates to the commercialization of the
Collaboration Product in the Field, and in such event, Fuso agrees not to oppose
such intervention. If Fuso is named as a party and GenVec shall, at any time,
tender its defense to Fuso, then Fuso shall defend GenVec in such claim, suit or
proceeding, at Fuso' s own expense and through counsel of its own choice, and
Fuso shall control the defense and settlement of any such claim, suit or
proceeding; provided, Fuso shall not enter into any agreement which makes any
admission regarding (i) wrongdoing on the part GenVec, or (ii) the invalidity,
unenforceability or absence of infringement of any GenVec Patent Rights or
patent claiming a Joint Technology, without the prior written consent of GenVec,
which consent shall not be unreasonably withheld. The parties shall cooperate
with each other in connection with any such claim, suit or proceeding and shall
keep each other reasonably informed of all material developments in connection
with any such claim, suit or proceeding.

8.   REPRESENTATIONS AND WARRANTIES

     8.1     WARRANTIES.

             8.1.1  GENVEC. GenVec warrants and represents to Fuso that (i) it
has the full right and authority to enter into this Agreement and grant the
rights and licenses granted herein; (ii) as of the Effective Date, except for
the interference proceedings pending in the U.S. Patent and Trademark Office,
there are no existing or threatened actions, suits or claims pending against

                                      -19-
<Page>

it with respect to the GenVec Technology or its right to enter into and perform
its obligations under this Agreement; (iii) it has not previously granted, and
will not grant during the Agreement Term, any right, license or interest in or
to GenVec Technology or Joint Technology, or any portion thereof, which are in
conflict with the rights or licenses granted under this Agreement; and (iv) as
of the Effective Date, GenVec believes that the list of patent applications and
patents contained in Exhibit A hereto is a complete list of patent applications
and patents owned or controlled by GenVec reasonably anticipated by GenVec to be
used for the conduct of the Research Program or the Collaboration Products.

             8.1.2  FUSO. Fuso warrants and represents to GenVec that (i) it has
the full right and authority to enter into this Agreement, and (ii) it has not
previously granted, and will not grant during the Agreement Term, any right,
license or interest in or to Fuso Technology or Joint Technology, or any portion
thereof, which are in conflict with the rights or licenses granted under this
Agreement.

     8.2     EFFECT OF REPRESENTATIONS AND WARRANTIES. It is understood that if
the representations and warranties under this Article 8 are not true and
accurate and GenVec or Fuso incurs liabilities, costs or other expenses as a
result of such falsity, GenVec or Fuso, as the case may be, shall indemnify,
defend and hold the other party harmless from and against any such liabilities,
costs or expenses incurred, provided that the indemnifying party receives prompt
notice of any claim against GenVec or Fuso, as the case maybe, resulting from or
related to such falsity, the cooperation of the indemnified party, as requested
in connection with any such claim, and the sole right to control the defense or
settlement thereof.

     8.3     DISCLAIMER OF WARRANTIES. GenVec and Fuso each specifically
disclaim that the Research Program will be successful, in whole or part. GENVEC
AND FUSO EXPRESSLY DISCLAIM ANY WARRANTIES, EXPRESS, IMPLIED, STATUTORY OR
OTHERWISE, WITH RESPECT TO THE CONFIDENTIAL INFORMATION, OR FUSO TECHNOLOGY OR
GENVEC TECHNOLOGY, INCLUDING, WITHOUT LIMITATION, ANY WARRANTY OF
MERCHANTABILITY, NONINFRINGEMENT, OR FITNESS FOR A PARTICULAR PURPOSE, VALIDITY
OF FUSO TECHNOLOGY OR GENVEC TECHNOLOGY, PATENTED OR UNPATENTED, OR
NONINFRINGEMENT OF THE INTELLECTUAL PROPERTY RIGHTS OF THIRD PARTIES.

9.   CONFIDENTIALITY

     9.1     CONFIDENTIAL INFORMATION. Except as expressly provided herein, the
parties agree that, for the Agreement Term, the receiving party shall keep
completely confidential and shall not publish or otherwise disclose and shall
not use for any purpose except for the purposes contemplated by this Agreement
any Confidential Information furnished to it by the disclosing party hereto
pursuant to this Agreement, except that to the extent that it can be established
by the receiving party by competent proof that such Confidential Information:

     (a)     was already known to the receiving party, other than under an
     obligation of confidentiality, at the time of disclosure;

     (b)     was generally available to the public or otherwise part of the
     public domain at the time of its disclosure to the receiving party;

                                      -20-
<Page>

     (c)     became generally available to the public or otherwise part of the
     public domain after its disclosure and other than through any act or
     omission of the receiving party in breach of this Agreement;

     (d)     was independently developed by the receiving party without
     reference to any information or materials disclosed by the disclosing
     party; or

     (e)     was subsequently disclosed to the receiving party by a person other
     than a party without breach of any legal obligation to the disclosing
     party.

     9.2     PERMITTED DISCLOSURES. Each party hereto may disclose another's
Confidential Information to the extent such disclosure is reasonably necessary
in connection with the conduct of the Research Program activities to be
conducted at any academic institution approved by the Steering Committee, in
filing or prosecuting patent applications, prosecuting or defending litigation,
complying with applicable governmental regulations or otherwise submitting
information to tax or other governmental authorities, conducting clinical
trials, making a permitted sublicense, securing funding or otherwise exercising
its rights hereunder, provided that if a party is required to make any such
disclosure of another party's confidential information, other than pursuant to a
confidentiality agreement, it will give reasonable advance notice to the latter
party of such disclosure and, save to the extent inappropriate in the case of
patent applications, will use its best efforts to secure confidential treatment
of such information prior to its disclosure (whether through protective orders
or otherwise).

     9.3     NON-DISCLOSURE. Each of the parties hereto agrees not to disclose
to any third party the financial terms of this Agreement without the prior
written consent of each other party hereto, except to advisors, investors and
others on a need to know basis under circumstances that reasonably ensure the
confidentiality thereof, or to the extent required by law. Without limitation
upon any provision of this Agreement, each of the parties hereto shall be
responsible for the observance by its employees of the foregoing confidentiality
obligations. Notwithstanding the foregoing, the parties shall agree upon a press
release to announce the execution of this Agreement, together with a
corresponding Q&A outline for use in responding to inquiries about the
Agreement; thereafter, GenVec and Fuso may each disclose to third parties the
information contained in such press release and Q&A without the need for further
approval by the other.

10.  INDEMNIFICATION

     10.1    INDEMNIFICATION OF FUSO. GenVec shall indemnify and hold Fuso and
its Affiliates, and their respective directors, officers, employees, agents and
counsel, and the successors and assigns of the foregoing (the "Fuso
Indemnitees"), harmless from and against any and all liabilities, damages,
losses, costs or expenses (including reasonable attorneys' and professional fees
and other expenses of litigation and/or arbitration) resulting from a claim,
suit or proceeding brought by a third party against a Fuso Indemnitee, arising
from or occurring as a result of: (i) GenVec's conduct of the Research Program,
(ii) the research, development, use or clinical testing of any Product
Configuration and/or Collaboration Product by GenVec or its Affiliates or
licensees other than Fuso and its Affiliates (including without limitation,
product liability claims), or (iii) the failure of Collaboration Products
manufactured by GenVec to meet

                                      -21-
<Page>

the relevant specifications, except, in each case, to the extent caused by the
negligence or willful misconduct of Fuso.

     10.2    INDEMNIFICATION OF GENVEC. Fuso shall indemnify and hold GenVec and
its Affiliates and their respective directors, officers, employees, agents and
counsel and the successors and assigns of the foregoing (the "GenVec
Indemnitees"), harmless from and against any and all liabilities, damages,
losses, costs or expenses (including reasonable attorneys' and professional fees
and other expenses of litigation and/or arbitration) resulting from a claim,
suit or proceeding brought by a third party against a GenVec Indemnitee, arising
from or occurring as a result of; (i) Fuso's conduct of the Research Program, or
(ii) the research, development, use or clinical testing of any Product
Configuration and/or Collaboration Product by Fuso or its Affiliates or
Sublicensees (including without limitation, product liability claims), except,
in each case, to the extent caused by the negligence or willful misconduct of
GenVec.

     10.3    PROCEDURE. A party (the "Indemnitee") that intends to claim
indemnification under this Article 10 shall promptly notify the other party (the
"Indemnitor") in writing of any loss, claim, damage, liability or action in
respect of which the Indemnitee or any of its Affiliates, Sublicensees or their
directors, officers, employees, agents or counsel intend to claim such
indemnification, and the Indemnitor shall have the right to participate in, and,
to the extent the Indemnitor so desires, to assume the defense thereof with
counsel mutually satisfactory to the parties. The indemnity agreement in this
Article 10 shall not apply to amounts paid in settlement of any loss, claim,
damage, liability or action if such settlement is made without the consent of
the Indemnitor, which consent shall not be withheld unreasonably. The failure to
deliver written notice to the Indemnitor within a reasonable time after the
commencement of any such action, if prejudicial to its ability to defend such
action, shall relieve such Indemnitor of any liability to the Indemnitee under
this Article 10. At the Indemnitor's request, the Indemnitee under this Article
10, and its employees and agents, shall cooperate fully with the Indemnitor and
its legal representatives in the investigation and defense of any action, claim
or liability covered by this indemnification and provide full information with
respect thereto.

11.  TERM AND TERMINATION

     11.1    TERM. This Agreement shall be effective as of the Effective Date
and, unless terminated earlier pursuant to Section 2.6.2 or the other provisions
of this Article 11, shall continue in full force and effect until the later of
(i) the date that research and clinical trials with respect to all Collaboration
Products have been discontinued, or (ii) the date for BLA approval with respect
to all Collaboration Products in the Territory (the "Agreement Term"); provided,
that unless this Agreement is terminated by GenVec pursuant to Section 11.2 or
11.3 or is terminated pursuant to Section 11.4 through 11.5, the license granted
to Fuso under Section 3.1 and the obligations set forth in Sections 5.1 and 5.2
and Article 6 shall remain in effect with respect to any Product Configuration
which prior to the effective date of such expiration or termination was
designated by the Steering Committee as a Collaboration Product on a
Collaboration Product-by-Collaboration Product basis, until the earlier of (i)
the date that research and clinical trials with respect to the applicable
Collaboration Product have been discontinued, or (ii) the date GenVec receives
payment for a BLA approval with respect to such Collaboration Product in the
Territory.

                                      -22-
<Page>

     11.2    TERMINATION FOR CAUSE. Either party may terminate this Agreement in
the event the other party has materially breached or defaulted in the
performance of any of its obligations hereunder, and such default has continued
for sixty (60) days after written notice thereof was provided to the breaching
party by the nonbreaching party. Any termination shall become effective at the
end of such sixty (60) day period unless the breaching party has cured any such
breach or default prior to the expiration of the sixty (60) day period.
Notwithstanding the above, in the case of a failure to pay any amount due
hereunder the period for cure of any such default following notice thereof shall
be ten (10) days and, unless payment is made within such period, the termination
shall become effective at the end of such period.

     11.3    TERMINATION FOR INSOLVENCY. If voluntary or involuntary proceedings
by or against a party are instituted in bankruptcy under any insolvency law, or
a receiver or custodian is appointed for such party, or proceedings are
instituted by or against such party for corporate reorganization or the
dissolution of such party, which proceedings, if involuntary, shall not have
been dismissed within sixty (60) days after the date of filing, or if such party
makes an assignment for the benefit of creditors, or substantially all of the
assets of such party are seized or attached and not released within sixty (60)
days thereafter, the other party may immediately terminate this Agreement
effective upon notice of such termination.

     11.4    PERMISSIVE TERMINATION. After the second anniversary of the
Effective Date, Fuso may, at its sole discretion, terminate this Agreement at
any time with ninety (90) days' prior notice pursuant to Section 2.6.2.

     11.5    TERMINATION OF COMMERCIALIZATION AGREEMENT. If the
Commercialization Agreement terminates, this Agreement shall terminate
concurrently.

     11.6    EFFECT OF BREACH OR TERMINATION.

             11.6.1 ACCRUED OBLIGATIONS. Termination of this Agreement for any
reason shall not release any party hereto from any liability which, at the time
of such termination, has already accrued to the other party or which is
attributable to a period prior to such termination, nor preclude either party
from pursuing any rights and remedies it may have hereunder or at law or in
equity which accrued or are based upon any event occurring prior to such
termination.

             11.6.2 RETURN OF MATERIALS. Upon the discontinuance of the research
and development activities with respect to a particular Product Configuration,
whether due to termination of this Agreement or otherwise, if a corresponding
Collaboration Product is not being commercialized pursuant to the
Commercialization Agreement, Fuso and GenVec shall promptly return to the other
party all materials and Confidential Information received from the other party
relating specifically to such Product Configuration (except one copy of which
may be retained by legal counsel for archival purposes); provided, however, that
the foregoing shall only apply to GenVec in the event this Agreement is properly
terminated by Fuso pursuant to Section 11.2 or 11.3.

             11.6.3 LICENSES. The licenses granted Fuso herein shall terminate
in the event of a termination pursuant to Section 11.2 (only in case of the
termination by GenVec), 11.3 (only in case of the termination by GenVec), 11.4
(subject to Section 11.1) or 11.5. To the extent the licenses granted to Fuso
survive the termination of this Agreement, any related provisions, including the
provision of Section 5, shall also survive the termination of this Agreement.

                                      -23-
<Page>

     11.7    SURVIVAL. Sections 2.4.5, 2.4.6, 2.5.1, 2.7, 3.2, 3.3, 5.3, 11.1,
11.6 and 11.7 and Articles 4, 7, 8, 9, 10, 12 and 13 shall survive the
expiration or termination of this Agreement for any reason.

12.  DISPUTE RESOLUTION

     12.1    MEDIATION. If a dispute arises out of or relates to this Agreement,
or the breach thereof, and if said dispute cannot be settled through
negotiation, the parties agree first to try in good faith to settle the dispute
by mediation under the Commercial Mediation Rules of the American Arbitration
Association before resorting to arbitration.

     12.2    ARBITRATION. Any dispute under this Agreement (except any dispute
relating to the validity or enforceability of any patent) which is not settled
by mutual consent shall be finally settled by binding arbitration. Such
arbitration shall be conducted in accordance with the International Arbitration
Rules of the Asia/Pacific Center by three (3) arbitrators appointed in
accordance with said rules and shall be held in San Francisco, California. At
least one of the arbitrators shall be an independent expert in pharmaceutical
product development (including clinical development and regulatory affairs). The
arbitrators shall determine what discovery will be permitted, consistent with
the goal of limiting the cost and time which the parties must expend for
discovery; provided the arbitrators shall permit such discovery as they deem
necessary to permit an equitable resolution of the dispute. Any written evidence
originally in a language other than English shall be submitted in English
translation accompanied by the original or a true copy thereof. The costs of the
arbitration including administrative and arbitrators' fees, shall be shared
equally by the parties and each party shall bear its own costs and attorneys'
and witness' fees incurred in connection with the arbitration. A disputed
performance or suspended performances pending the resolution of the arbitration
must be completed within thirty (30) days following the final decision of the
arbitrators or such other reasonable period as the arbitrators determine in a
written opinion. Any arbitration subject to this Article shall be completed
within one (1) year from the filing of notice of a request for such arbitration.
No punitive damages may be granted by the arbitrators. The arbitration
proceedings and the decision shall not be made public without the joint consent
of the parties and each party shall maintain the confidentiality of such
proceedings and decision unless otherwise permitted by the other party. The
parties agree that the decision shall be the sole, exclusive and binding remedy
between them regarding any and all disputes, controversies, claims and
counterclaims presented to the arbitrators. Any award may be entered in a court
of competent jurisdiction for a judicial recognition of the decision and an
order of enforcement.

13.  MISCELLANEOUS

     13.1    GOVERNING LAW. This Agreement and any dispute arising from the
performance or breach hereof shall be governed by and construed in accordance
with the laws of the State of California, without reference to conflicts of laws
principles.

     13.2    WAIVER. Neither party may waive or release any of its rights or
interests in this Agreement except in writing. The failure of either party to
assert a right hereunder or to insist upon compliance with any term or condition
of this Agreement shall not constitute a waiver of that right or excuse a
similar subsequent failure to perform any such term or condition.

                                      -24-
<Page>

     13.3    ASSIGNMENT. This Agreement shall not be assignable by either party
to any third party hereto without the written consent of the other party hereto;
except either party may assign this Agreement, without such consent, to (i) an
Affiliate of such party; or (ii) an entity that acquires all or substantially
all of the business or assets of such party to which this Agreement pertains,
whether by merger, reorganization, acquisition, sale, or otherwise, and that
agrees in writing to be strictly bound by the terms and conditions of this
Agreement. The terms and conditions of this Agreement shall be binding on and
inure to the benefit of the permitted successors and assigns of the parties.

     13.4    NOTICES. Any notices, requests and other communications hereunder
shall be in writing and shall be personally delivered or sent by international
express delivery service, registered or certified mail, return receipt
requested, postage prepaid, in each case to the respective address specified
below, or such other address as may be specified in writing to the other parties
hereto:

     FUSO:

             Fuso Pharmaceutical Industries, Ltd.
             3-11, 2-Chome, Morinomiya, Joto-ku
             Osaka 536, Japan
             Attn: President

             With a copy to:     Director, Research and Development Center

     GENVEC:

             GenVec, Inc.
             65 West Watkins Mill Road
             Gaithersburg, Maryland 20878, U.S.A.

             Attn: President

             With a copy to:     Senior Vice President, Corporate Development

     13.5    PERFORMANCE WARRANTY. Fuso and GenVec hereby respectively warrant
and guarantee the performance of any and all rights and obligations of this
Agreement by their Affiliate(s) and sublicensees.

     13.6    FORCE MAJEURE. Neither party shall be liable to the other for
failure or delay in the performance of any of its obligations under this
Agreement for the time and to the extent such failure or delay is caused by
earthquake, riot, civil commotion, war, hostilities between nations,
governmental law, order or regulation, embargo, action by the government or any
agency thereof, act of God, storm, fire, accident, labor dispute or strike,
sabotage, explosion or other similar or different contingencies, in each case,
beyond the reasonable control of the respective party. The party affected by
force majeure shall provide the other party with full particulars thereof as
soon as it becomes aware of the same (including its best estimate of the likely
extent and duration of the interference with its activities), and will use its
best endeavors to overcome the difficulties created thereby and to resume
performance of its obligations as soon as

                                      -25-
<Page>

practicable. If the performance of any obligation under this Agreement is
delayed owing to a force majeure for any continuous period of more than six (6)
months, the parties hereto shall consult with respect to an equitable solution
including the possible termination of this Agreement.

     13.7    INDEPENDENT CONTRACTORS. Nothing contained in this Agreement is
intended implicitly, or is to be construed, to constitute Fuso or GenVec as
partners in the legal sense. No party hereto shall have any express or implied
right or authority to assume or create any obligations on behalf of or in the
name of any other party or to bind any other party to any contract, agreement or
undertaking with any third party.

     13.8    ADVICE OF COUNSEL. GenVec and Fuso have each consulted counsel of
their choice regarding this Agreement, and each acknowledges and agrees that
this Agreement shall not be deemed to have been drafted by one party or another
and will be construed accordingly.

     13.9    OTHER OBLIGATIONS. Except as expressly provided in this Agreement
or as separately agreed upon in writing between GenVec and Fuso, each party
shall bear its own costs incurred in connection with the implementation of the
obligations under this Agreement.

     13.10   INDEPENDENT RESEARCH. Except as expressly provided herein, each
party acknowledges and agrees that Fuso and GenVec shall have the right to
engage in their own research and development activities outside the Research
Program. Neither party shall, by virtue of this Agreement, have any right, title
or interest in or to such independent activities or to the income or profits
derived therefrom.

     13.11   SEVERABILITY. In the event that any provisions of this Agreement
are determined to be invalid or unenforceable by a court of competent
jurisdiction, the remainder of the Agreement shall remain in full force and
effect without said provision. The parties shall in good faith negotiate a
substitute clause for any provision declared invalid or unenforceable, which
shall most nearly approximate the intent of the parties in entering this
Agreement; provided, if the parties are unable to agree on such a substitute
clause and the deletion of the provision held invalid or unenforceable would
produce material adverse financial consequences for one party, such party shall
have the right to terminate the Agreement with one hundred eighty (180) days
notice.

     13.12   FURTHER ASSURANCES. At any time or from time to time on and after
the date of this Agreement, either party shall at the request of the other party
(i) deliver to the requesting party such records, data or other documents
consistent with the provisions of this Agreement, (ii) execute, and deliver or
cause to be delivered, all such consents, documents or further instruments of
assignment, transfer or license, and (iii) take or cause to be taken all such
actions, as the requesting party may reasonably deem necessary or desirable in
order for the requesting party to obtain the full benefits of this Agreement and
the transactions contemplated hereby.

     13.13   FOREIGN CORRUPT PRACTICES ACT. In conformity with the United States
Foreign Corrupt Practices Act, Fuso and its employees and agents shall not
directly or indirectly make any offer, payment, promise to pay, or authorize
payment, or offer a gift, promise to give, or authorize the giving of anything
of value for the purpose of influencing an act or decision of an official of any
government within the Territory or the United States Government (including a

                                      -26-
<Page>

decision not to act) or inducing such official to use his influence to affect
any such governmental act or decision in order to obtain, retain, or direct any
such business.

     13.14   EXPORT LAWS. Notwithstanding anything to the contrary contained
herein, all obligations of GenVec and Fuso are subject to prior compliance with
United States export regulations and such other United States or Japanese laws
and regulations as may be applicable, and to obtaining all necessary approvals
required by the applicable agencies of the government of the United States or
Japan. GenVec and Fuso, respectively, shall each use its best efforts to obtain
such approvals from its own government. Each party shall cooperate with the
other party and shall provide assistance to the other party as reasonably
necessary to obtain any required approvals.

     13.15   APPROVALS. Each party shall be responsible, at its expense, for
obtaining any approvals from its own government which may be required under
applicable law, and shall use its best efforts to obtain all necessary approvals
as soon as possible after the execution of this Agreement.

     13.16   ENTIRE AGREEMENT. This Agreement, including the attached Exhibits,
and the Commercialization Agreement of even date herewith, constitute the entire
agreement between the parties with respect to the subject matter hereof, and
supersede all prior or contemporaneous understandings or agreements, whether
written or oral, between Fuso and GenVec with respect to such subject matter.
Each party specifically agrees that the Collaboration Agreement and the
Commercialization Agreement between the parties, each dated September 26, 1997,
and the Letter Agreement and Amendment of Letter Agreement dated April 1, 2002
and September 9, 2002 respectively, each of which references such agreements,
are hereby terminated as of the Effective Date. Each party acknowledges that, to
its knowledge, the other party performed all its financial and research
obligations thereunder. The foregoing shall in no way limit those obligations
that expressly survive the termination of such agreements.

     13.17   HEADINGS. The captions to the several Sections and Articles hereof
are not a part of this Agreement, but are included merely for convenience of
reference only and shall not affect its meaning or interpretation.

     13.18   COUNTERPARTS. This Agreement may be executed in two counterparts,
each of which shall be deemed an original and which together shall constitute
one instrument.

IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be duly
     executed by their authorized representatives as of the Effective Date.

FUSO PHARMACEUTICAL                              GENVEC, INC.
INDUSTRIES, LTD.

By:    /s/ Mikio Toda                    By:    /s/ Paul H. Fischer
      -----------------------------            ------------------------

Name:  Mikio Toda                        Name:  Paul H. Fischer
      -----------------------------            ------------------------

Title: President and Representative      Title: President and C.E.O.
       Director                                ------------------------
      -----------------------------

                                      -27-
<Page>

                                   EXHIBIT A:
                         GENVEC JAPANESE PATENT RIGHTS

A.   JAPANESE PATENTS

*

B.   JAPANESE PATENT APPLICATIONS

*

C.   PCT APPLICATIONS DESIGNATING JAPAN

*

D.   U.S. APPLICATIONS WITH UNEXPIRED CONVENTION PERIODS (i.e., JAPANESE
          COUNTERPART APPLICATIONS CAN BE FILED)

*

                                      -28-

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