Document:

Exhibit 10.1

 

 

FIRST
AMENDMENT TO 

FIRST
AMENDED 2007 STock INCENTIVE PLAN

 

This
First Amendment (the “First Amendment”) to that certain First Amended 2007 Stock Incentive Plan (the “2007
Plan”) of Bio-Path Holdings, Inc., a Utah corporation (the “Company”), is made effective as of the
8th day of August, 2013. All capitalized and undefined terms used herein shall have the meanings ascribed to such terms
in the 2007 Plan.

 

WHEREAS, pursuant to
Section 21 of the 2007 Plan, the board of directors (the “Board”) of the Company is authorized to amend the
2007 Plan; and

 

WHEREAS, the Board
unanimously approved an amendment to the 2007 Plan as set forth herein.

 

NOW, THEREFORE, in
connection with the foregoing, the 2007 Plan is hereby amended as follows:

 

1.                 
The last sentence of Section 2.1 of the 2007 Plan is hereby deleted in its entirety and replaced
with the following:

 

“Subject to
adjustment in accordance with Section 18.4, in any calendar year, no Participant shall be granted Awards in respect of more than
1,500,000 shares of Common Stock (whether through grants of options or SARs or other Awards of Common Stock or rights with respect
thereto).”

 

2.                 
Except as amended and modified by this First Amendment, the 2007 Plan shall continue in full
force and effect, and the 2007 Plan and this First Amendment shall be construed as one and the same instrument.

 

IN WITNESS WHEREOF,
the Company executed this First Amendment as of the date first above written.

 

	 	BIO-PATH HOLDINGS, INC.
	 	 
	 	By: 	/s/ Peter H. Nielsen
	 	Name:	Peter H. Nielsen
	 	Title:	President and Chief Executive OfficerSUBSCRIPTION AGREEMENT

 

This
SUBSCRIPTION Agreement (this “Agreement”) is made as of February 20, 2013 by and between CNS Response,
Inc., a Delaware corporation (the “Company”), and the investor listed on Schedule A hereto (each, an
“Investor” and together, the “Investors”).

 

Agreement

 

In consideration for
the mutual promises and covenants herein, the parties agree as follows:

 

WHEREAS, the Company
is offering in a private placement up o $2.5 million of its common stock, par value $.0001 per share (“Shares”
or “Common Stock”) for $.25 per share in a private placement to accredited investors pursuant to a Confidential
Offering Memorandum dated February 20, 2013; and

 

WHEREAS, the undersigned
desires to subscribe for and purchase the number of Shares set forth on Schedule A hereto.

 

Section
1 – Purchase and Sale of SHARES

 

1.1Purchase
and Sale of Shares. The Company has authorized the issuance and sale, in accordance
with the terms hereof, of shares of Common Stock, in the aggregate amount of up to $2,500,000 (the “Shares
Cap Amount”). On the terms and subject to the conditions set forth in this Agreement, at
the Closings (as defined below), the Company agrees to issue to each Investor, and the Investor agrees to purchase from the Company,
in the amount set forth on Schedule A.
The Company will sell Shares to more than one Investor, each of whom will enter into Subscription Agreement substantially identical
to this one. The financing pursuant to which the Company is issuing the Shares is hereinafter referred to as the “Financing”.

 

1.2Closings.

 

(a)Initial
Closing. The initial purchase and sale of the Shares shall take place at a closing (the “Initial Closing”)
which shall take place remotely via exchange of documents and signatures at 10:00 a.m. Eastern Time on the business day immediately
following execution and delivery of this Agreement, or at such other place and time as may be agreed to among the Company and the
Investors. At the Initial Closing, the Company shall deliver to each of the Investors purchasing Securities for cash at such closing
a certificate or certification representing such number of Shares as is set forth opposite such Investor’s name on Schedule
A under the column entitled “Purchase Price (Initial Closing)” against receipt of a check subject to collection
or a wire transfer in immediately available funds of the purchase price, to an account designated by the Company. 

 

(b)Additional
Closings. The Company shall have the right, on one or more occasions, to hold additional closings (each, an “Additional
Closing”, and collectively with the Initial Closing, the “Closings”,
and individually, a “Closing”), pursuant to which it shall have the right
to issue and sell additional Shares to additional Investors or existing Investors (provided that no Additional Closings shall take
place later than April 30, 2013). At each Additional Closing, the Company shall deliver to each Investor purchasing Shares at such
closing a certificate or certification representing such number of Shares as is in set forth opposite such Investor’s name
on Schedule A under the column entitled “Purchase Price” against receipt
of a check subject to collection or a wire transfer in immediately available funds of the purchase price, to an account designated
by the Company. By receiving Shares at an Additional Closing, each Investor so receiving Shares thereby represents that its representations
and warranties contained in Section 3 are true and correct as of the date of such Additional Closing. The aggregate principal amount
of Shares that may be issued at Closings hereunder shall, in no event exceed the Share Cap Amount.

 

    	 

    	 

    

 

The obligation of each
Investor to purchase and pay cash for the Shares to be delivered at a Closing is, unless waived by such Investor, subject to the
condition that the Company’s representations and warranties contained in Section 2 are true, complete and correct on and
as of such Closing date. The obligation of the Company to sell and issue Shares to be delivered at a Closing is, unless waived
by the Company, subject to the condition that the relevant Investor’s representations and warranties contained in Section
3 are true, complete and correct on and as of the Closing Date.

 

 

Section
2 - Representations and Warranties

of
the Company

 

The Company represents
and warrants to each Investor as follows:

 

2.1Existence
of Company. The Company is a duly organized Delaware corporation. The Company is validly existing in all jurisdictions where
it conducts its business.

 

2.2Authority to Execute.
The execution, delivery and performance by the Company of this Agreement and the issuance of the Shares are within the Company’s
corporate powers, have been duly authorized by all necessary corporate action, do not and will not conflict with any provision
of law or organizational document of the Company (including its Certificate of Incorporation or Bylaws) or of any agreement or
contractual restrictions binding upon or affecting the Company or any of its property and need no further stockholder or creditor
consent.

 

2.3No Stockholder
Approval Required. No approval of the Company’s stockholders is required for (i) the entry by the Company into this Agreement,
or (ii) the issuance of the Shares contemplated by this Agreement.

 

2.4Valid Issuance.
The Shares will be, validly issued, fully paid and nonassessable and free of restrictions on transfer other than restrictions on
transfer under, applicable state and federal securities laws and liens or encumbrances created by or imposed by the Investor. Assuming
the accuracy of the representations of the Investor in Section 3 of this Agreement, and the Shares will be issued in compliance
with all applicable federal and state securities laws.

 

    	 

    	 

    

 

2.5Binding
Obligation. This Agreement is, a valid and binding obligation of the Company enforceable against the Company in accordance
with its terms, subject, as to enforcement of remedies, to applicable bankruptcy, insolvency, moratorium, reorganization and similar
laws affecting creditors’ rights generally and to general equitable principles.

 

2.6Litigation.
Other than the litigation disclosed in the Company’s most recent SEC Reports (as defined below), no litigation or governmental
proceeding is pending or threatened against the Company which may have a materially adverse effect on the financial condition,
operations or prospects of the Company, and to the knowledge of the Company, no basis therefore exists.

 

2.7Intellectual
Property. To the best of the Company’s knowledge, the Company owns or possesses sufficient legal rights to all patents,
trademarks, service marks, trade names, copyrights, trade secrets, licenses, information and other proprietary rights and processes
necessary for its business as now conducted and as presently proposed to be conducted, without any known infringement of the rights
of others. There are no outstanding options, licenses or agreements of any kind relating to the foregoing proprietary rights, nor
is the Company bound by or a party to any options, licenses or agreements of any kind with respect to the patents, trademarks,
service marks, trade names, copyrights, trade secrets, licenses, information and other proprietary rights and processes of any
other person or entity other than such licenses or agreements arising from the purchase of “off the shelf” or standard
products.

 

2.8SEC Reports.The
Company has filed all forms, reports, schedules, proxy statements, registration statements and other documents (including all exhibits
thereto) required to be filed by it with the Securities and Exchange Commission (the “SEC”) pursuant to the
federal securities laws and the SEC rules and regulations thereunder, together with all certifications required pursuant to the
Sarbanes-Oxley Act of 2002 (the “Sarbanes-Oxley Act”) (as they have been amended since the time of their filing,
including all exhibits thereto, the “SEC Reports”). Each of the SEC Reports complied in all material respects
with the applicable requirements of the Securities Act of 1933, as amended (the “Securities Act”) and the Securities
Exchange Act of 1934, as amended (the “Exchange Act”), the Sarbanes-Oxley Act and the rules and regulations
of the SEC under all of the foregoing. None of the SEC Reports contained any untrue statement of a material fact or omitted to
state a material fact required to be stated therein or necessary in order to make the statements therein, in light of the circumstances
under which they were made, not misleading.

 

Section
3 - Representations and Warranties

of
the Investors

 

Each Investor represents
and warrants to the Company as follows:

 

3.1Authorization;
Binding Obligations. The Investor has full power and authority to enter into this Agreement and this Agreement constitutes
a valid and legally binding obligation of the Investor, enforceable against the Investor in accordance with its terms, subject,
as to enforcement of remedies, to applicable bankruptcy, insolvency, moratorium, reorganization and similar laws affecting creditors’
rights generally and to general equitable principles.

 

    	 

    	 

    

 

3.2Accredited
Investor. The Investor is an “accredited investor” within the meaning of SEC Rule 501 of Regulation D promulgated
under the Securities Act.

 

3.3Investment
for Own Account. The Shares are being acquired for his, her or its own account, for investment and not with a view to, or for
resale in connection with, any distribution or public offering thereof within the meaning of the Securities Act.

 

3.4Knowledge
and Experience. The Investor has such knowledge and experience in financial and business matters that (s)he is capable of evaluating
the merits and risks of an investment in the Shares and of making an informed investment decision with respect thereto, has the
ability and capacity to protect his/her interests and can bear the economic risk of the acceptance of the Shares, including a total
loss of his/her investment.

 

3.5 Opportunity
to Ask Questions. The Investor has had the opportunity to ask questions and receive answers from the Company or any authorized
person acting on its behalf concerning the Company and its business and to obtain any additional information, to the extent possessed
by the Company (or to the extent it could have been acquired by the Company without unreasonable effort or expense) necessary to
verify the accuracy of the information received by the Investor. In connection therewith, the Investor acknowledges that (s)he
has had the opportunity to discuss the Company’s business, management and financial affairs with the Company’s management
or any authorized person acting on its behalf.

 

3.6.Receipt
of Information. The Investor has received and reviewed all the information concerning the Company, the Securities and the Shares,
both written and oral, that the Investor desires. Without limiting the generality of the foregoing, the Investor has been furnished
with or has had the opportunity to acquire, and to review: all information, both written and oral, that the Investor desires with
respect to the Company’s business, management, financial affairs and prospects. In determining whether to make this investment,
the Investor has relied solely on his/her own knowledge and understanding of the Company and its business and prospects based upon
the Investor’s own due diligence investigations and the Company’s filings with the SEC.

 

Section
4 - Miscellaneous

 

4.1No Waiver;
Cumulative Remedies. No failure or delay on the part of any party to this Agreement in exercising any right or remedy under,
or pursuant to, this Agreement shall operate as a waiver thereof, nor shall any single or partial exercise of any such right, remedy
or power preclude other or further exercise thereof, or the exercise of any other right, remedy or power. The remedies in this
Agreement are cumulative and are not exclusive of any remedies provided by law.

 

4.2Amendments
and Waivers. Except as otherwise expressly set forth in this Agreement, any term of this Agreement may be amended (either retroactively
or prospectively) with the written consent of the Company and the Investor. Any amendment effected in accordance with this Section
4.2 shall be binding upon each Investor, each future holder of Securities and the Company.

 

    	 

    	 

    

 

4.3Notices,
Etc. All notices, requests, consents and other communications hereunder to any party shall be deemed to be sufficient if contained
in a written instrument delivered in person; sent by facsimile transmission; sent by electronic mail; duly sent by first class
registered or certified mail, return receipt requested, postage prepaid; or duly sent by overnight delivery service (e.g.,
Federal Express) addressed to such party (i) if to the Company, at the address, fax number or electronic mail address, as applicable,
set forth on the signature page hereof or (ii) if to an Investor, at the address, fax number or electronic mail address, as applicable,
set forth on Schedule A hereto, or at such other address, fax number or electronic mail address as may hereafter be designated
in writing by the addressee to the sender. All such notices, advises and communications shall be deemed to have been received:
(a) in the case of personal delivery, on the date of such delivery; (b) in the case of facsimile or electronic mail transmission,
on the date of transmission; and (c) in the case of mailing or delivery by service, on the date of delivery as shown on the return
receipt or delivery service statement.

 

4.4Governing
Law. This Agreement shall be governed by and construed in accordance with the laws of the State of California, without regard
to the conflicts of law provisions of the State of California or of any other state. The Company and each Investor consent to personal
jurisdiction in Orange County, California.

 

4.5Severability.
If any term in this Agreement is held to be illegal or unenforceable, the remaining portions of this Agreement shall not be affected,
and this Agreement shall be construed and enforced as if this Agreement did not contain the term held to be illegal or unenforceable.

 

4.6Binding Effect.
This Agreement shall be binding upon and inure to the benefit of the Company and each Investor and their respective successors
and assigns.

 

4.7Transfer
of Shares. Notwithstanding the legend required to be placed on the Shares by applicable law, no registration statement or opinion
of counsel shall be necessary: (a) for a transfer of Shares to the respective estate of each Investor or for a transfer of Shares
by gift, will or intestate succession of each Investor to his or her spouse or to the siblings, lineal descendants or ancestors
each Investor or his or her spouse, if the transferee agrees in writing to be subject to the terms hereof to the same extent as
if he or she were the original Investor hereunder; or (b) for a transfer of Shares pursuant to SEC Rule 144 or any successor rule,
or for a transfer of Shares pursuant to a registration statement declared effective by the SEC under the Securities Act relating
to the Securities.

 

4.8Survival
of Representations, Warranties and Covenants. The representations and warranties of the parties contained in or made pursuant
to this Agreement shall survive the execution and delivery of this Agreement indefinitely, and shall in no way be affected by any
investigation of the subject matter thereof made by or on behalf of the other parties. The covenants of the parties contained in
or made pursuant to this Agreement shall survive the execution and delivery of this Agreement until such time as the Notes have
been paid in full.

 

4.9California
Commissioner of Corporations. THE SALE OF THE SECURITIES WHICH ARE THE SUBJECT OF THIS AGREEMENT HAS NOT BEEN QUALIFIED WITH
THE COMMISSIONER OF CORPORATIONS OF THE STATE OF CALIFORNIA AND THE ISSUANCE OF THE SECURITIES OR PAYMENT OR RECEIPT OF ANY PART
OF THE CONSIDERATION FOR SUCH SECURITIES PRIOR TO THE QUALIFICATION IS UNLAWFUL, UNLESS THE SALE OF SECURITIES IS EXEMPT FROM QUALIFICATIONS
BY SECTION 25100, 25102 OR 25105 OF THE CALIFORNIA CORPORATIONS CODE. THE RIGHTS OF ALL PARTIES TO THIS AGREEMENT ARE EXPRESSLY
CONDITIONED UPON SUCH QUALIFICATION BEING OBTAINED, UNLESS THE SALE IS SO EXEMPT.

 

[Remainder of Page Intentionally Left
Blank]

 

    	 

    	 

    

  

IN WITNESS WHEREOF,
the parties hereto have caused this Agreement to be duly executed and delivered by their proper and duly authorized officers as
of the date first written above.

 

 

	 	CNS RESPONSE, INC. 
	 	 	 
	 	 	 
	 	By:	 
	 	 	Name: Paul Buck
	 	 	Title:   Chief Financial Officer
	 	 	 
	Address/Fax Number/E-mail Address for Notice:	 	 
	 	 	 
	85 Enterprise, Suite 410	 	 
	Aliso Viejo, CA 92656	 	 
	Fax: (866) 867 4446	 	 
	pbuck@cnsresponse.com	 	 
	 	 	 
	 	 	 
	 	 	INVESTOR:
	 	 	 
	 	 	 
	 	By:	 
	 	 	Name:
	 	 	 
	 	 	Title: 
	 	 	 

 

[SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT]

 

    	 

    	 

    

 

SCHEDULE A

 

	Name, Address, Fax Number, E-Mail Address of Investor and Tax ID Number	
        Aggregate Purchase Price 

         

	
         

         

         

         

         

         

         

        Fax#:__________________________________

         

        Email:_________________________________

         

        TaxID:_________________________________

         
	
         

         

         

        $______________________

	TOTAL:

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