Document:

EX-4.1

 Exhibit 4.1 

Execution Version 

AMENDMENT NO. 2 

AMENDMENT NO. 2 TO THE AMENDED AND RESTATED CREDIT AGREEMENT, dated as of November 18, 2021 (this
“Amendment”), among THE SHERWIN-WILLIAMS COMPANY, an Ohio corporation (the “Company”), the Lenders party hereto, GOLDMAN SACHS BANK USA (“GS Bank”), as Administrative Agent (in
such capacity, the “Administrative Agent”), and GOLDMAN SACHS MORTGAGE COMPANY (“GSMC”), as Issuing Bank (in such capacity, the “Issuing Bank”). Capitalized terms not otherwise
defined in this Amendment have the same meanings as specified in the Credit Agreement referred to below. 
 PRELIMINARY STATEMENTS:

 (1) The Company, the Administrative Agent, the Lenders from time to time party thereto and the Issuing Bank are parties to that
certain Amended and Restated Credit Agreement, dated as of August 2, 2021 (as amended by Amendment No. 1 to the Amended and Restated Credit Agreement, dated as of August 6, 2021, the “Existing Credit
Agreement”; the Existing Credit Agreement as amended by this Amendment, the “Credit Agreement”). 
 (2)
The Company has requested, and the Administrative Agent and the Lenders have agreed, on the terms and conditions set forth herein, to amend the Existing Credit Agreement as specified herein. 

NOW, THEREFORE, in consideration of the premises and for other good and valuable consideration, the receipt and sufficiency of which is hereby
acknowledged, the parties hereto hereby agree as follows: 
 SECTION 1. Amendments to the Existing Credit Agreement. Upon, and
subject to, the satisfaction or waiver in accordance with Section 9.02 of the Existing Credit Agreement of the conditions precedent set forth in Section 2 below, the Existing Credit Agreement is hereby amended as follows: 

(a) The following new definition is included in Section 1.01 of the Existing Credit Agreement in the proper alphabetical
order as follows: 
 ““Amendment No. 2 Effective Date” means
November 18, 2021.” 
 (b) Each of the following definitions in Section 1.01 of the Existing Credit Agreement
is hereby amended and restated in its entirety as follows: 
 ““Commitment” means, with respect
to each Lender, the commitment of such Lender to acquire participations in the Letter of Credit and to make Loans, as such commitment may be (a) reduced from time to time pursuant to Section 2.07, (b) reduced or increased from time to time
pursuant to assignments by or to such Lender pursuant to Section 9.04 or (c) reduced or increased from time to time pursuant to an amendment hereto. The amount of each Lender’s Commitment on the Amendment No. 2 Effective Date is
set forth on Schedule 2.01, or in the Assignment and Acceptance pursuant to which such Lender shall have assumed its Commitment, as applicable.” 

  

					
		  	1	  	 THE SHERWIN-WILLIAMS COMPANY

Amendment No. 2 to Credit Agreement

 ““Maturity Date” means June 20, 2026;
provided, however, that (i) with respect to the Commitments in the aggregate amount of $300,000,000, the Maturity Date shall mean December 20, 2022, (ii) with respect to the Commitments in the aggregate amount of $125,000,000, the
Maturity Date shall mean June 20, 2023, (iii) with respect to the Commitments in the aggregate amount of $125,000,000, the Maturity Date shall mean June 20, 2026, and (iv) with respect to the Commitments in the aggregate amount of
$75,000,000, the Maturity Date shall mean December 20, 2026.” 
 (c) Schedule 2.01 of the Existing Credit Agreement is hereby
amended and restated in its entirety as set forth in Schedule 2.01 attached hereto. 
 SECTION 2. Conditions of Effectiveness. This
Amendment shall become effective on the date (the “Amendment No. 2 Effective Date”) on which: 

(a) the Administrative Agent shall have received a counterpart signature page of this Amendment duly executed by (i) the Company,
(ii) the Administrative Agent, (iii) the Lenders, and (iv) the Issuing Bank or, as to any of the foregoing parties, written evidence reasonably satisfactory to the Administrative Agent that such party has executed this Amendment; 

(b) the Administrative Agent shall have received one or more counterparts of the Fifth Amended and Restated Letter Agreement, dated as of the
date hereof, duly executed by the Company and GSMC; and 
 (c) the representations and warranties set forth in Section 4 of this
Amendment shall be true and correct in all respects. 
 SECTION 3. Effect of this Amendment, Etc. 

(a) Except as expressly set forth herein, this Amendment shall not by implication or otherwise limit, impair, constitute a waiver of, or
otherwise affect the rights and remedies of the Issuing Bank, the Lenders or the Administrative Agent under the Credit Agreement or any other Loan Document, and shall not alter, modify, amend or in any way affect any of the terms, conditions,
obligations, covenants or agreements contained in the Credit Agreement or any other Loan Document, all of which are ratified and affirmed in all respects and shall continue in full force and effect. 

(b) Nothing herein shall be deemed to entitle the Company to a consent to, or a waiver, amendment, modification or other change of, any of the
terms, conditions, obligations, covenants or agreements contained in the Credit Agreement or any other Loan Document in similar or different circumstances. 

(c) After the Amendment No. 2 Effective Date, each reference in any Loan Document to the Credit Agreement, to “this Agreement”,
“hereunder”, “hereof” or words of like import referring to the Credit Agreement, shall mean and be a reference to the Existing Credit Agreement, as modified hereby. This Amendment shall constitute a “Loan Document” for
all purposes of the Credit Agreement and the other Loan Documents. 

  

					
		  	2	  	 THE SHERWIN-WILLIAMS COMPANY

Amendment No. 2 to Credit Agreement

 SECTION 4. Representations and Warranties. The Company represents and warrants to the
Administrative Agent and the Lenders that, on and as of the date hereof and on and as of the Amendment No. 2 Effective Date: 
 (a) (i)
The execution, delivery and performance by the Company of this Amendment and the transactions contemplated hereby have been duly authorized by all necessary corporate action, and (ii) this Amendment has been duly executed and delivered by the
Company and constitutes a legal, valid and binding obligation of the Company, enforceable against the Company in accordance with its terms, except as may be limited by applicable bankruptcy, insolvency, fraudulent transfer, reorganization,
moratorium or similar laws of general applicability relating to or affecting creditors’ rights generally and subject to general principals of equity, regardless of whether considered in a proceeding in equity or at law. 

(b) The representations and warranties of the Company contained in the Credit Agreement and any other Loan Document are true and correct in
all material respects, except to the extent such representations and warranties expressly relate to an earlier date (in which case such representations and warranties are true and correct in all material respects as of such earlier date). 

(c) Both before and after giving effect to this Amendment, no Default or Event of Default has occurred and is continuing. 

SECTION 5. Execution in Counterparts. This Amendment may be executed in counterparts (and by different parties hereto on different
counterparts), each of which shall constitute an original, but all of which when taken together shall constitute a single contract, it being understood and agreed that the words “execution,” “signed,” “signature,” and
words of similar import in, or with respect to, this Amendment shall be deemed to include electronic signatures or the keeping of records in electronic form (including, without limitation, the execution by means of “DocuSign”, or other
similar platform or service approved by the Administrative Agent), each of which shall be of the same effect, validity and enforceability as manually executed signatures or a paper-based recordkeeping system, as the case may be, to the extent and as
provided for under applicable law, including the Electronic Signatures in Global and National Commerce Act of 2000 (15 USC § 7001 et seq.), the Electronic Signatures and Records Act of 1999 (NY State Technology Law §§ 301-309), or any other similar state laws based on the Uniform Electronic Transactions Act; provided, that any electronic signature delivered by means of “DocuSign”, or other similar third-party platform
by one party shall be at the request of any other party hereto promptly followed by an email attestation by such party to the recipient party confirming that such electronic signature so delivered is the signature of such party; provided, further,
that upon the request of the Administrative Agent, any electronic signature shall be followed by a manually executed counterpart as promptly as reasonably practicable. 

SECTION 6. Governing Law. This Amendment shall be governed by, and construed in accordance with, the laws of the State of New York.

  

					
		  	3	  	 THE SHERWIN-WILLIAMS COMPANY

Amendment No. 2 to Credit Agreement

 SECTION 7. WAIVER OF JURY TRIAL. EACH PARTY HERETO HEREBY WAIVES, TO THE FULLEST
EXTENT PERMITTED BY APPLICABLE LAW, ANY RIGHT IT MAY HAVE TO A TRIAL BY JURY IN ANY LEGAL PROCEEDING DIRECTLY OR INDIRECTLY ARISING OUT OF OR RELATING TO THIS AMENDMENT OR THE TRANSACTIONS CONTEMPLATED HEREBY (WHETHER BASED ON CONTRACT, TORT OR ANY
OTHER THEORY). EACH PARTY HERETO (A) CERTIFIES THAT NO REPRESENTATIVE, AGENT OR ATTORNEY OF ANY OTHER PARTY HAS REPRESENTED, EXPRESSLY OR OTHERWISE, THAT SUCH OTHER PARTY WOULD NOT, IN THE EVENT OF LITIGATION, SEEK TO ENFORCE THE FOREGOING
WAIVER AND (B) ACKNOWLEDGES THAT IT AND THE OTHER PARTIES HERETO HAVE BEEN INDUCED TO ENTER INTO THIS AGREEMENT BY, AMONG OTHER THINGS, THE MUTUAL WAIVERS AND CERTIFICATIONS IN THIS SECTION. 

SECTION 8. Jurisdiction; Consent to Service of Process. 

(a) The Company hereby irrevocably and unconditionally submits, for itself and its property, to the nonexclusive jurisdiction of the Supreme
Court of the State of New York sitting in New York County and of the United States District Court of the Southern District of New York, and any appellate court from any thereof, in any action or proceeding arising out of or relating
to this Amendment, or for recognition or enforcement of any judgment, and each of the parties hereto hereby irrevocably and unconditionally agrees that all claims in respect of any such action or proceeding may be heard and determined in such
New York State or, to the extent permitted by law, in such Federal court. Each of the parties hereto agrees that a final judgment in any such action or proceeding shall be conclusive and may be enforced in other jurisdictions by suit on the
judgment or in any other manner provided by law. Nothing in this Amendment shall affect any right that the Administrative Agent or any Lender or the Issuing Bank may otherwise have to bring any action or proceeding relating to this Amendment against
the Company or its properties in the courts of any jurisdiction. 
 (b) The Company hereby irrevocably and unconditionally waives, to the
fullest extent it may legally and effectively do so, any objection which it may now or hereafter have to the laying of venue of any suit, action or proceeding arising out of or relating to this Amendment in any court referred to in
subsection (b) of this Section. Each of the parties hereto hereby irrevocably waives, to the fullest extent permitted by law, the defense of an inconvenient forum to the maintenance of such action or proceeding in any such court. 

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK] 

  

					
		  	4	  	 THE SHERWIN-WILLIAMS COMPANY

Amendment No. 2 to Credit Agreement

 IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be executed by
their respective officers thereunto duly authorized, as of the date first above written. 
  

			
	THE SHERWIN-WILLIAMS COMPANY
		
	By:	 	/s/ Jeffrey J. Miklich
		 	Name: Jeffrey J. Miklich
		 	Title: Vice President and Treasurer

  

					
		  		  	 THE SHERWIN-WILLIAMS COMPANY

Amendment No. 2 to Credit Agreement

 
			
	GOLDMAN SACHS BANK USA,
as Administrative Agent and as Lender
		
	By:	 	/s/ Rebecca Kratz
		 	Name: Rebecca Kratz
		 	Title: Authorized Signatory

  

					
		  		  	 THE SHERWIN-WILLIAMS COMPANY

Amendment No. 2 to Credit Agreement

 
			
	GOLDMAN SACHS MORTGAGE COMPANY,
	as Issuing Bank
	
	By: Goldman Sachs Real Estate Funding Corp., its General Partner
		
	By:	 	/s/ Charles Johnston
		 	Name: Charles Johnston
		 	Title: Authorized Signatory

  

					
		  		  	 THE SHERWIN-WILLIAMS COMPANY

Amendment No. 2 to Credit Agreement

 SCHEDULE 2.01 

To 
 Credit Agreement

 Commitments 
  

					
	 Lender
	  	Commitment	 
	 Goldman Sachs Bank USA
	  	$	625,000,000.00	 
		  	  
	  
	 
	 Total:
	  	$	625,000,000.00	 
		  	  
	  
	 

 (continued below) 

Scheduled Reductions in the Aggregate Commitments 
  

			
	Aggregate Scheduled Reduction ($) in the Total Commitment(s) and
Commitment of the Issuing Bank (without duplication)	  	Date on Which Scheduled Reduction Takes Effect
	 $300,000,000
	  	December 20, 2022
		
	 $125,000,000
	  	June 20, 2023
		
	 $125,000,000
	  	June 20, 2026
		
	 $75,000,000
	  	December 20, 2026

  

					
		  	Schedule 2.01 – 1	  	 THE SHERWIN-WILLIAMS COMPANY

Amendment No. 2 to Credit AgreementExhibit
10.1

 

180
Life Sciences Corp. 

CONSULTING
AGREEMENT

 

This
Consulting Agreement (this “Agreement”) is made and entered into on November 17, 2021, to be effective as of
November 1, 2021 (the “Effective Date”) by and between 180 Life Sciences Corp., a Delaware corporation (the
“Company”), and Lawrence Steinman, M.D., an individual (“Consultant”) (each herein
sometimes referred to individually as a “Party”, or collectively as the “Parties”).

 

WHEREAS,
the Consultant was appointed as an Executive Co-Chairman of the Board of Directors of the Company (the “Co-Chairman”),
effective November 6, 2020; and

 

WHEREAS,
the Company desires to engage Consultant to provide services to the Company as the Co-Chairman of the Company pursuant to the terms and
conditions of this Agreement, and the Consultant desires to accept such engagement.

 

NOW,
THEREFORE, in consideration of the foregoing and the terms, covenants, and conditions hereinafter set forth, the Parties hereto,
intending to be legally bound hereby, mutually agree as follows:

 

1.
Position and Duties. The Company hereby engages Consultant as the Executive Co-Chairman of the Board of Directors (the “Board”)
of the Company. As such, Consultant shall have the responsibilities, duties and authority reasonably expected of an Executive Co-Chairman
of the Board, as more specifically set forth on Exhibit A hereto and as may be further defined by, or amended by, the Board from
time to time). In addition to Co-Chairman of the Board, Consultant also has primary scientific responsibility for the Company’s
á7nAChR platform. In this capacity, the Consultant shall provide the full benefit of his knowledge, expertise, technical skill
and ingenuity in connection with the primary scientific responsibility for the Company’s á7nAChR platform and shall devote
his time, attention and abilities to the scientific development for the Company’s á7nAChR platform at such times as may be
necessary for the proper performance of his duties. Consultant hereby accepts this engagement upon the terms and conditions herein contained
and agrees to devote as much of his professional time, attention, and efforts as necessary to promote and further the business of the
Company. All of the services outlined above constitute collectively, the “Services”. Consultant shall faithfully
adhere to, execute, and fulfill his responsibilities, duties and authorities, and shall comply with all Board directives and policies
established or adopted by the Company. Subject to the restrictions set forth in Section 7 of this Agreement, if during the Term,
Consultant desires to render services to any other organization, prior to agreeing to provide those services, he shall receive the consent
of the Board, after disclosing to the Board in writing the identity of the organization and the nature of the services to be performed,
which consent shall not be unreasonably withheld, conditioned or delayed. Services rendered to other organizations as of the Effective
Date, have been disclosed to the Company. Consultant represents and warrants that Consultant has no agreements, relationships, or commitments
to any other person or entity that conflict with the provisions of this Agreement, Consultant’s obligations to the Company under
this Agreement, or Consultant’s ability to perform the Services. Consultant will not enter into any such conflicting agreement
during the term of this Agreement.

 

2.
Term. 

 

(a)
Consultant’s engagement under this Agreement shall be for a three (3) year period beginning on the Effective Date and ending on
the day preceding the third anniversary of the Effective Date (the “Initial Term”); provided that this Agreement
shall automatically extend for additional one (1) year periods after the Initial Term (each an “Automatic Renewal Term”
and the Initial Term together with all Automatic Renewal Terms, if any, the “Term”), subject to the Renewal
Requirements, in the event that neither Party provides the other written notice of their intent not to automatically extend the term
of this Agreement at least thirty (30) days prior to the end of the Initial Term or any Automatic Renewal Term, as applicable (each a
“Non-Renewal Notice”). The Term shall only be extended for an Automatic Renewal Term, provided that with regards
to being Co-Chairman (i) Consultant is re-elected to the Board at the Annual Meeting of Stockholders of the Company immediately preceding
the date that such Automatic Renewal Term begins; (ii) the Board affirms his appointment as Co-Chairman for the applicable Automatic
Renewal Term (or fails to appoint someone else as Co-Chairman prior to such applicable Automatic Renewal Term) and (iii) the Consultant
is continuing in his role of having the responsibility for the scientific development for the Company’s á7nAChR platform
(collectively, the “Renewal Requirements”).

 

    Consulting Agreement
Page 1 of 8

     

    

 

(b)
The Term shall expire immediately upon the earlier of: (i) the date upon which Consultant no longer serves as Co-Chairman and no longer
has primary scientific responsibility for our á7nAChR platform; and (ii) any earlier date requested by either (1) the Company (as
evidenced by a vote of a majority of the Board (excluding Consultant) at a meeting of the Board), or (2) Consultant (as evidenced by
written notice from Consultant to the Board). Additionally, the Company may terminate this Agreement immediately and without prior notice
if Consultant is unable or refuses to perform the Services, and either Party may terminate this Agreement immediately and without prior
notice if the other Party is in breach of any material provision of this Agreement.

 

(b)
The terms of this Agreement may be amended from time to time, with the mutual consent of the Board (or the Compensation Committee of
the Board) and the Consultant.

 

3.
Compensation. The Company shall provide Consultant the following compensation in exchange for the Services:

 

(a)
Cash Compensation. During the Term, the Company shall pay Consultant an annual fee of $225,000 (the “Salary”).
The Salary shall be payable in regular installments in accordance with the normal payroll practices of the Company, in effect from time
to time, but in any event no less frequently than on a monthly basis. This Salary replaces all current cash compensation being paid to
the Consultant under previous consulting agreements. In addition, the Consultant will receive a one time payment of $43,750 for the difference
between the previous salary and the new Salary since April 1, 2021. The Compensation Committee and/or the Audit Committee of the Company,
shall review the Salary not less than once per calendar year, beginning with calendar year 2023, and as of January 1 of such year, during
each Automatic Renewal Term, and determine whether any increase in the Salary is warranted, based upon such criteria as it deems relevant,
and any increase in Salary, if any, shall not be required to be set forth in an amendment to the Agreement, but can instead solely be
noted in the minutes of the Compensation Committee, the Audit Committee and/or Board of the Company, which shall become the “Salary”
payable hereunder for all purposes.

 

(b)
Expenses. The Company shall reimburse Consultant for all ordinary and reasonable out-of-pocket business expenses incurred by him
in connection with his performance of services for the Company during the Term, provided Consultant submits an expense reimbursement
request and supporting documentation in accordance with the Company’s expense reimbursement policy in effect from time to time.

 

(c)
Equity Award. Upon the next open trading window as determined by the Board of Directors in their reasonable discretion, it is
anticipated that, subject to approval of such award in their discretion, that the Board will grant the Consultant incentive stock options
to purchase twenty five thousand (25,000) shares of the Company’s common stock (the “Options”). The actual
grant date will be in the discretion of the Board of Directors and the Options shall have a term of ten (10) years; an exercise price
equal to the Fair Market Value of the Company’s common stock on the date of grant, as defined in the Company’s 2020 Omnibus
Incentive Plan (the “Plan”), shall be subject to such Plan, shall be evidenced by a stock option agreement
entered into by the Company, and shall vest immediately upon the date of grant. Such Options shall be subject to such other provisions
to be set forth in the applicable grant agreement(s) to be entered into between Consultant and the Company. In addition, beginning in
calendar year 2022, for each year during the Term of this Agreement, the Company will, subject to future approval by the Board of Directors
of the Company, grant to Consultant $125,000 of value of equity. Future equity grants will vest over a 48 month period and be in accordance
with the Plan. Timing of the future grants, nature of the equity grants (e.g., RSU, PSU, restricted stock, etc.) and any changes in the
value of future equity will be recommended by the Company’s Compensation Committee and/or Audit Committee and approved by the Board.
Neither the Options described above, nor any future equity grants shall be effective until or unless approved by the Board of Directors.

 

4.
Compensation Upon Termination. On the date this Agreement terminates pursuant to Section 2, the Company shall pay Consultant
the fees earned under Section 3(a) through the effective date of termination and reimburse any reasonable expenses incurred on
or prior to the effective date of termination under Section 3(b). If following the termination of this Agreement, Consultant remains
a director of the Company, he shall be entitled to receive any compensation otherwise payable to him as a director.

 

    Consulting Agreement
Page 2 of 8

     

    

 

5.
Confidentiality. In connection with his engagement under this Agreement, Consultant will be exposed to, and may develop or
create, certain information concerning the business, data, results, programs, processes and techniques, customers and other information
and materials that embody trade secrets or technical or business information that is confidential and proprietary to the Company (collectively,
“Confidential Information”). Consultant hereby agrees not to disclose or use, other than in connection with
his Services performed for the Company or its affiliates, any Confidential Information without the Company’s prior, written consent,
unless such information becomes publicly available through no fault of Consultant or a third party obligated by contract or other legal
duty to keep such information confidential. Consultant further agrees not to make any notes or memoranda relating to the business of
the Company, other than for the Company’s benefit. In addition, Consultant agrees promptly upon the Company’s request to
return to the Company or permanently destroy (at the Company’s option) any and all documentary, machine-readable, electronic, magnetic
or other elements or evidence based on or containing Confidential Information and any copies that may be in Consultant’s possession
or under his control. Consultant also agrees, upon the request of the Company, to provide the Company, all electronically-stored information
and passwords to access such property related to the Company, and any reproductions of any of the foregoing items that Consultant may
have in Consultant’s possession or control. The provisions of this Section 5 shall apply both during and after the Term.

 

6.
Independent Contractor; Tax Consequences.

 

(a)
It is the express intention of the Company and Consultant that Consultant perform the Services as an independent contractor to the Company.
Nothing in this Agreement shall in any way be construed to constitute Consultant as an agent or employee of the Company. Without limiting
the generality of the foregoing, Consultant is not authorized to bind the Company to any liability or obligation or to represent that
Consultant has any such authority. Consultant acknowledges and agrees that Consultant is obligated to report as income all compensation
received by Consultant pursuant to this Agreement. Consultant agrees to and acknowledges the obligation to pay all self-employment and
other taxes on such income. The Company and Consultant agree that Consultant will receive no Company-sponsored benefits from the Company.

 

(b)
The Company makes no representations or warranties with respect to the tax consequences of the payments and any other consideration provided
to Consultant under the terms of this Agreement. Consultant agrees and understands that he is responsible for payment, if any, of local,
state, and/or federal taxes on the payments and any other consideration provided hereunder by the Company and any penalties or assessments
thereon. Consultant agrees to indemnify and hold harmless the Company and its affiliates and their directors, officers and employees
from and against all taxes, losses, damages, liabilities, costs and expenses, including attorneys’ fees and other legal expenses,
arising from or in connection with (i) any obligation imposed on the Company to pay withholding taxes or similar items, (ii) any determination
by a court or agency that the Consultant is not an independent contractor.

 

(c)
Consultant is solely responsible for, and will file, on a timely basis, all tax returns and payments required to be filed with, or made
to, any federal, state or local tax authority with respect to the performance of services and receipt of fees under this Agreement. Consultant
is solely responsible for, and must maintain adequate records of, expenses incurred in the course of performing services under this Agreement.
Contractor will comply with all applicable federal, state, local, and foreign laws governing self-employed individuals, including laws
requiring the payment of taxes, such as income and employment taxes, and social security, disability, and other contributions. No part
of Consultant’s compensation will be subject to withholding by the Company for the payment of any social security, federal, state
or any other employee payroll taxes. The Company will regularly report amounts paid to Consultant by filing Form 1099-MISC with the Internal
Revenue Service as required by law.

 

7.
Noninterference; Non-Solicitation; Non-Competition.

 

(a)
To the fullest extent permitted under applicable law, from the Effective Date, until twelve (12) months after the termination of this
Agreement for any reason (the “Restricted Period”), Consultant will not, without the Company’s prior
written consent, either directly or indirectly solicit, induce, recruit or encourage any of the Company’s employees with whom he
has worked and/or about whom he has received material, Confidential Information during his engagement hereunder, to leave their employment,
or take away such employees, or attempt to solicit, induce, recruit, encourage or take away employees of the Company, either for himself
or any other person or entity. During the period of time he is a Consultant, Consultant will not, whether for Consultant’s own
account or for the account of any other person, firm, corporation or other business organization, intentionally interfere with any person
who is or during the period of Consultant’s engagement by the Company was a partner, supplier, customer or client of the Company
or its affiliates.

 

    Consulting Agreement
Page 3 of 8

     

    

 

(b)
During the Term, Consultant shall not, alone or as a partner, officer, director, consultant, employee, stockholder or otherwise, engage
in any commercial employment, consulting or business activity, occupation or other activity that is or is intended to be competitive
with the Company, unless otherwise approved by the Board in writing, provided, however, that the holding by Consultant of any investment
in any security shall not be deemed to be a violation of this Section 7(b) if such investment does not constitute over five percent
(5%) of the outstanding issue of such security.

 

8.
Intellectual Property. The Parties foresee that the Consultant may make, conceive, develop and/or create Intellectual Property
Rights in the course of providing the Services.

 

(1)
In this clause:

 

(a)
“Intellectual Property Rights” means patents, rights to Inventions, copyrights and related rights,
trademarks and service marks, trade names and domain names, rights in get-up, goodwill and the right to sue for passing off or
unfair competition, rights in designs, rights in computer software, database rights, rights to preserve the confidentiality of
information (including know-how and trade secrets) and any other intellectual property rights, in each case whether registered or
unregistered and including all applications (or rights to apply for and be granted), renewals or extensions of, and rights to claim
priority from, such rights, and all similar or equivalent rights or forms of protection which subsist or will subsist now or in the
future in any part of the world, that relate to the business of the Company;

 

(b)
“Inventions” means inventions, ideas and improvements that relate to the business of the Company, whether
or not patentable, and whether or not recorded in any medium; and

 

(c)
“IP Materials” means all records, reports, documents, papers, drawings, designs, typographical
arrangements, software, photographic or graphic works of any type, and all other materials in any medium or format, which are
created by or on behalf of the Consultant in the course of providing the Services and that relate to the business of the
Company.

 

(2)
The Consultant hereby assigns to the Company all existing or future Intellectual Property Rights that relate to the business of the Company
which arise in the course of performing the Services (including without limitation the IP Materials, all present and future copyright,
and copyright revivals, and extensions). This assignment shall take effect immediately on the creation of each of the Intellectual Property
Rights and without payment to the Consultant, other than the Salary.

 

(3)
The Consultant agrees to sign all documents and do all other acts and things which the Company requests (at its expense) to enable the
Company to enjoy the full benefit of this Section 8. This includes joining in any application which may be made for registration of any
Intellectual Property Rights (such as a patent, trade mark or registered design) arising in the course of, or in connection with, providing
the Services.

 

(4)
The Consultant agrees that it may only use the Intellectual Property Rights and IP Materials to perform his obligations under this Agreement,
and shall not disclose any Intellectual Property Rights or IP Materials to any third party without the express prior written consent
of the Company.

 

(5)
The Consultant waives all moral rights or equivalent rights in other jurisdictions in IP Materials to which he would otherwise be entitled
under the law of any relevant jurisdiction.

 

    Consulting Agreement
Page 4 of 8

     

    

 

(6)
The Consultant shall immediately transfer to the Company all IP Materials in his/her possession or under his control when this Agreement
expires or terminates for any reason, or at any time when the Company requests. No copies or other record of any IP Materials may be
retained by the Consultant except with the prior written consent of the Company.

 

(7)
The Consultant hereby irrevocably appoints the Company to be its attorney in his name or on his/her behalf to sign, execute or do any
instrument or thing and generally to use his name for the purpose of giving to the Company or its nominee the full benefit of the provisions
of this clause. A certificate in writing signed by any director or the secretary of the Company that any instrument or act falls within
the authority conferred by this clause shall be conclusive evidence that such is the case so far as any third party is concerned.

 

(8)
This clause shall survive expiry of this Agreement, or its termination for any reason.

 

9.
Special Remedy. The restrictions in Sections 5 and 7 and the terms of Section 8 of this Agreement shall survive the termination
of this Agreement and are necessary for the protection of the Company’s business and goodwill. Consultant acknowledges that the
restrictions are reasonable and that any breach or threatened breach of Sections 5, 7 or 8 of this Agreement will cause the Company substantial
and irreparable damage. Accordingly, in the event of any breach or threatened breach of Sections 5, 7 or 8 of this Agreement, in addition
to any other remedies that may be available by contract or at law, the Company shall have the right to seek specific performance by Consultant
and to seek temporary, preliminary and permanent relief enjoining Consultant from any breach or threatened breach, without the posting
of any bond or other similar measures.

 

10.
Miscellaneous.

 

(a)
Governing Law; Consent to Personal Jurisdiction; Remedies. This Agreement shall be governed by the laws of the State of California.
To the extent that any lawsuit is permitted under this Agreement, the Parties hereby expressly consent to the personal and exclusive
jurisdiction and venue of the state and federal courts located in California. Consultant’s obligations under this Agreement are
of a unique character that gives them particular value; breach of any of such obligations will result in irreparable and continuing damage
to the Company for which there will be no adequate remedy at law; and, in the event of such breach, the Company will be entitled to injunctive
relief and/or a decree for specific performance, and such other and further relief as may be proper (including monetary damages if appropriate).

 

(b)
Assignability. This Agreement will be binding upon Consultant’s heirs, executors, assigns, administrators, and other
legal representatives, and will be for the benefit of the Company, its successors, and its assigns. Consultant may not sell, assign or
delegate any rights or obligations under this Agreement. Company may assign this Agreement and its rights and obligations under this
Agreement to any successor to all or substantially all of Company’s relevant assets, whether by merger, consolidation, reorganization,
reincorporation, sale of assets or stock.

 

(c)
 Entire Agreement. This Agreement constitutes the entire agreement and understanding between the Parties with respect
to the subject matter herein and supersedes all prior written and oral agreements, discussions, or representations between the Parties.
Consultant represents and warrants that he is not relying on any statement or representation not contained in this Agreement.

 

    Consulting Agreement
Page 5 of 8

     

    

 

(d)
Severability. If a court or other body of competent jurisdiction determines any provision of this Agreement, or portion
thereof, to be invalid or unenforceable, such provision will be enforced to the maximum extent permissible so as to effect the intent
of the Parties, and the remainder of this Agreement will continue in full force and effect.

 

(e)
Modification, Waiver. No modification of or amendment to this Agreement, nor any waiver of any rights under this Agreement,
will be effective unless in a writing signed by the Parties. Waiver by the Company of a breach of any provision of this Agreement will
not operate as a waiver of any other or subsequent breach.

 

(f)
Notices. All notices, approvals, consents, requests, and other communications hereunder shall be in writing and shall be
delivered (i) by personal delivery, or (ii) by national overnight courier service, or (iii) by certified or registered mail, return receipt
requested, or (iv) via facsimile transmission, with confirmed receipt, or (v) via email. Notice shall be effective upon receipt except
for notice via fax (as discussed above) or email, which shall be effective only when the recipient, by return or reply email or notice
delivered by other method provided for in this Section 10(f), acknowledges having received that email (with an automatic “read
receipt” or similar notice not constituting an acknowledgement of an email receipt for purposes of this Section 10(f),
or but which acknowledgement of acceptance shall include cases where recipient ‘replies’ to such prior email). Such notices
shall be sent to the applicable party or Parties at the address specified on the signature page hereof.

 

(1)
If to the Company, to:

 

James
Woody, CEO

 

(2)
If to Consultant, to the address for notice on the signature page to this Agreement or, if no such address is provided, to the last address
of Consultant provided by Consultant to the Company.

 

(g)
Attorneys’ Fees. In any court action at law or equity that is brought by one of the Parties to this Agreement to enforce
or interpret the provisions of this Agreement, the prevailing Party will be entitled to reasonable attorneys’ fees, in addition
to any other relief to which that Party may be entitled.

 

(h)
Captions. The captions, headings and titles of the sections of this Agreement are inserted merely for convenience and ease of
reference and shall not affect or modify the meaning of any of the terms, covenants or conditions of this Agreement.

 

(i)
Counterparts. This Agreement and any signed agreement or instrument entered into in connection with this Agreement, and any amendments
hereto or thereto, may be executed in one or more counterparts, all of which shall constitute one and the same instrument. Any such counterpart,
to the extent delivered by means of a facsimile machine or by .pdf, .tif, .gif, .peg or similar attachment to electronic mail shall be
treated in all manners and respects as an original executed counterpart and shall be considered to have the same binding legal effect
as if it were the original signed version thereof delivered in person.

 

[Remainder
of page left intentionally blank. Signature page follows.]

 

    Consulting Agreement
Page 6 of 8

     

    

 

IN
WITNESS WHEREOF, the Parties hereto have executed this Consulting Agreement to be effective as of the Effective Date.

 

	CONSULTANT
     	 	180
    Life Sciences Corp.
	 	 	 	 
	/s/
    Lawrence Steinman   	 	By:	/s/
                                       James N. Woody

	Signature
     	 	Name:  	James
    N. Woody
	Name:
    Lawrence Steinman	 	Title:	CEO
	 	 	 	 
	Address
    for Notice:  	 	 	 
	1020
    Vernier Place Stanford CA 94305   	 	 	 

 

    Consulting Agreement
Page 7 of 8

     

    

 

EXHIBIT A

 

Duties
of the Co-Chairman 

 

The
Co-Chairman will have a substantial influence in the Company but will not actively participate in day-to-day operations. The Co-Chairman
will have the following primary responsibilities:

 

Strategic
and Business Development 

 

		●	Participate
                                            in defining and setting strategic objectives of the company

		●	Actively
                                            seek out acquisition and merger candidates

 

Capital
Formation

 

		●	Assist
                                            the Company with funding transactions and sourcing capital

 

Scientific

 

		●	Primary
                                            scientific responsibility for the Company’s á7nAChR platform

		●	Active
                                            participation in the Scientific Advisory Board

 

General

 

		●	At
                                            the request of the CEO, the Chairman may meet with various groups (such as major shareholder
                                            groups), governments, the financial press, industry associations, etc.

		●	Acts
                                            as a liaison between management and the Board

		●	Provides
                                            independent advice and counsel to the CEO

		●	Ensures
                                            that regularly, upon completion of the ordinary business of a meeting of the Board, the Directors
                                            hold discussions without management present

		●	Works
                                            closely with, and through the CEO, to:

		o	Participate
                                            in the development of the Company’s vision, strategic agenda, and business plan to
                                            facilitate communication and understanding between management and the Board and

		o	Ensure
                                            operations conform with the Board’s view on corporate policy

		●	In
                                            conjunction with the CEO, participates in external relationships which fulfill the Company’s
                                            obligations as a member of industry and the community

		●	Provides
                                            the key link between the Board and management, and as a result, has a significant communication,
                                            coaching and team-building responsibility including:

		o	Maintaining
                                            a close ongoing relationship and open communication with the CEO;

		●	Carries
                                            out special assignments in collaboration with the CEO and management or the Board of Directors.

 

 

Consulting
Agreement

Page
8 of 8

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00336-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00336-of-00352.parquet"}]]