Document:

Exhibit 10.40

 

LEASE AGREEMENT AND OTHER ARRANGEMENTS

 

By the terms in this lease agreement
of a land portion,

 

I. 
As LESSOR: USINA SÃO MARTINHO S/A., with registered office at Fazenda São Martinho, in the city of
Pradópolis - SP, registered with the Taxpayers’ Registry of the Ministry of Finance under no. CNPJ/MF 48.663.421/0001-29,
herein represented by its Agribusiness Officer, , and its Administrative Officer, ;

 

II. 
As LESSEE: SMA - INDÚSTRIA QUÍMICA S/A, with registered office at Fazenda São Martinho, in the
city of Pradópolis - SP, with pending Taxpayers’ Registry of the Ministry of Finance, herein represented by its Plant
Director, ; and its Director: ,

 

enter into this “lease agreement
of a land portion and other arrangements”, to be governed under the terms in the current laws and according to the following
conditions:

 

1. PROPERTY

 

1.1. The LESSOR
is the legitimate owner and holder of the rural property named “Fazenda São Martinho”, located in the city of
Pradópolis - SP, registered with INCRA in a larger area under No. 613.070.000.744-0 and with the Revenue Office under No.
0.780.459-8 under registry No. 357 in Book 2-RG in the Registrar of Properties in the County of Guariba - SP.

 

2. OBJECT

 

2.1. The object
of this agreement is the lease of a portion of land, hereinafter referred to as “property” with approximately 48,500
(forty-eight thousand and five hundred) square meters, according to the attached preliminary planimetric survey, separated from
the respective property, where the LESSEE is to build and operate its renewable chemicals production plant.

 

2.1.1. This
lease is agreed upon between the Parties under a joint venture established by the same parties, under the Joint Venture
Agreement executed on April 14, 2010 (the “Joint Venture Agreement”).

 

2.1.2.
The parties agree that the measurements of the leased property may be increased or decreased according to the needs of the industrial
plant presented by the LESSEE.

 

3. TERM

 

3.1. The term of the lease
is 20 (twenty) years, starting on May 1, 2010 and ending on April 30, 2030, when the LESSEE agrees upon returning the property
leased hereunder.

 

[Signatures]

    
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[Signatures]
[circular stamp] Amyris Legal

    

    

 

4. RENTAL FEE AND
PAYMENT

 

4.1. Rent is to
be monthly and the rental fee is to be calculated by square meter made available for deployment of the industrial plant, which
shall be timely paid by the LESSEE, by the 5th (fifth) working day each month, directly to the LESSOR,
by means of deposit into the account No. .

 

4.1.1. The parties
agree that the LESSEE shall be exempted from the payment of rent in the period from May 1, 2010 to December 31, 2010 or
until approval of the construction of the industrial plant by the Board of Directors of the LESSEE, whichever occurs first,
and rental payment shall commence therefrom.

 

4.1.2. Notwithstanding
the above-mentioned grace period, the Parties recognize that, in accordance with the terms in the Joint Venture Agreement
and in order to make the joint venture object of that agreement feasible, from the time of execution of this Agreement, the property
must be made available by the LESSOR to the LESSEE free from any encumbrance and the LESSEE shall employ its
best efforts to ensure to the LESSEE the possession of the property.

 

4.1.3. Following
the period of exemption from the payment of rents set forth under the terms in clause “4.1.1” herein, the LESSOR
shall set forth, according to current market prices for properties in the area where the property qualified in item 1.1 is located,
the price per square meter for purposes of rental payment, by means of amendment to this agreement, which shall be paid by the
LESSEE under terms set forth in this agreement.

 

4.2. The receipt
of the rental after the date set forth shall be considered mere tolerance and liberty by the LESSOR, with no prejudice whatsoever
to any of the terms in this agreement.

 

4.3. The LESSEE
agrees that the payment after the set forth date shall not represent settlement of obligations that are not charged at the right
time, especially rental differences and fees set forth in this agreement, and it is hereby agreed that the terms in Article 322
in the Civil Code shall not apply.

 

4.4. The deposits
of payments in check shall be effective, following respective compensation. Should the bank refuse to pay, for any reason, the
LESSEE is immediately subject to interest, as result of the non-existence of settlement.

 

4.5. Failure to present
timely payment of rent, at the agreed upon date, shall imply a two per cent (2%) fine over the adjusted value, with interest rate
at one per cent (1%) a month, incurring over the adjusted value, and the LESSEE shall also be subject to the consequences
of default set forth hereunder this agreement or in the law, especially the filing of eviction claim due to lack of payment, and
the LESSEE shall be responsible for the adjusted rental fee, added with interest and fees of ten per cent (10%), in the
amicable phase, or twenty per cent (20%), with the filing of a judicial claim.

 

4.6. If, during the
term of this agreement, or during the tacit extension of the lease, the rent is not paid on the due date and/or when payable by
the LESSEE with the proper addition, by mistake by the LESSOR, this shall not be deemed as amendment to this clause,
reason why the amount due by the LESSEE due to the payment of lower amount and/or resulting from [sic] of legal additions,
as soon as calculated and notified, shall be paid, regardless of months passed and that were not subject to the appropriate increase.

 

    
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[Signatures]
[circular stamp] Amyris Legal

    

    

 

5. ADJUSTMENT

 

5.1. The rental
fee will be adjusted, annually, according to the IGPM-FGV variation.

 

5.1.1.Should there
be any legislative changes to the frequency of rental adjustments, for period shorter than twelve (12) months, the new period shall
immediately apply to this agreement and in case of eventual legal omission of such frequency, it is hereby agreed that it shall
be monthly, when at the effectiveness of the new law, the monthly rent shall be adjusted according to the inflation rate measured
from the beginning or the last adjustment, as the case may be.

 

5.1.2.Should the
rate to be used for adjustment of the rent or default debts is terminated or frozen, the parties hereby choose the IGP (FGV), as
alternative for the adjustment of rents and, in lack thereof, the rate set forth by the Federal Government for the adjustment of
non-residential leases.

 

6.          
 VACANCY AND RETURN

 

6.1. The LESSEE
agrees upon formalizing the return of the property to the LESSOR or whoever is duly authorized, by the LESSOR, upon
receipt, when the acceptance of the property shall not imply settlement of obligations agreed upon by the LESSEE, regarding
rents, fees, and expenses for damages caused to the property.

 

6.2. Neither the
LESSOR, or its legal representatives, shall bear any responsibility before the LESSEE in case of fire, even when
caused by short-circuit, damages or defects in the electrical facilities, that may occur at industrial plant of the LESSEE.

 

6.3. Should the
LESSEE vacate the property for any reason (agreement termination, eviction, abandonment, etc.), leaving goods or belongings
behind, the LESSOR may, at its sole discretion, dispose of them as deemed to be appropriate.

 

7.          
 EXTENSION

 

7.1. Upon termination
of this agreement, with extension of the lease by law or convenience of the parties, all the terms and conditions agreed upon hereunder
shall be deemed to be extended, to govern the relation between the parties until final and effective vacancy and formal return
of the property.

 

8.          
INSPECTION

 

8.1. The LESSEE
hereby declares to have inspected the leased property, receiving it in perfect order for construction of the industrial plant.

 

9.          
RESPONSIBILITY FOR CONSTRUCTION OF THE INDUSTRIAL PLANT

 

9.1. The LESSEE
shall be solely and exclusively responsible for the construction of the industrial plant and its respective operation, including
regarding approval and operating licenses that may be required, with competent public bodies, with no costs for the LESSOR,
which is exempted from each and every responsibility.

 

9.2. Under no circumstance,
under penalty of contractual termination and fine, the LESSEE shall give to the property any destination other than that
set forth in the object of this agreement.

 

    
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[Signatures]
[circular stamp] Amyris Legal

    

    

 

10.SUBLEASE

 

10.1. The LESSEE
shall not assign or transfer this agreement to any third-party, without prior and formal consent “in writing” by
the LESSOR, and such consent, under no circumstance, may be deemed as implied.

 

11. PENALTY CLAUSE

 

11.1. The party that
infringes this agreement, in any of the clauses and conditions, shall pay to the other party a fine equal to three rents current
at the time of the infringement, and without prejudice to the right of the innocent party to require compliance with the agreement
or deem the agreement to be terminated.

 

11.2. The fine
does not exempt the LESSEE from the payment of eventual damages caused to the property.

 

11.3. If this agreement
is extended for indefinite term, the LESSEE may terminate the lease, upon written notice to the LESSOR, at least
thirty (30) days in advance.

 

12. SUCCESSORS

 

12.1. Clauses
and conditions of this agreement bind the successors at any title.

 

13. SPECIAL TERMS

 

13.1. The LESSEE
is hereby required to respond to notifications by public entities, agreeing upon not engaging, and preventing any engagement, with
illegal use or practices, under limitations of the property.

 

13.2. Should the LESSEE
intend to annotate or register this agreement, all the incurring expenses shall be solely borne by it, and it shall also be responsible
for, at its costs, the cancellation of the annotation or registry, upon termination of this agreement.

 

13.3. The LESSEE
shall be solely responsible for the following expenses, without limitation, required for construction of the industrial plant:

 

(i) 
Civil work related to the industrial plant

(ii) 
Asphalt pavement on the roads to access the industrial plant;

(iii) 
Electric power connection and consumption;

(iv) 
Water connection and consumption;

(v)  
Maintenance and repair at the industrial plant and other benefits to the property;

(vi) 
Gardening services in general;

(vii) 
Removal of waste or debris;

(viii) 
Construction of fence surrounding the perimeter of the property object of this agreement;

(ix) 
Security services;

(x)  
Telephone connection and consumption;

(xi) 
Retention of employees and their services.

 

13.4. Circulation
to access the property object of this agreement, by employees, third-parties, or vehicles, shall be according to pathways established
in the blueprint attached that, being initialed by the parties, shall be part of this agreement.

 

    
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[Signatures]
[circular stamp] Amyris Legal

    

    

 

14. APPLICABLE
LAW

 

14.1.    
This lease is to be governed by the terms in Law No. 8,245/91 and other applicable laws.

 

15. VENUE

 

15.1.    
All the conflicts arising out of this agreement shall be solved by the Courts in the County of Guariba - SP.

 

In witness whereof, the parties execute
this agreement in two counterparts of equal tenor for one sole purpose, before two witnesses.

 

Pradópolis, May 1, 2010

 

SÃO MARTINHO S/A

LESSOR

 

	
        [Signature]

        

        Mario Ortiz Gandini

        Agribusiness Officer
	
        [Signature]

        Roberto Pupulin

        Administrative Officer

 

SMA INDÚSTRIA QUÍMICA
S/A

Lessee

 

	
        [Signature]

        Mauro Pini França

        Plant Director
	
        [Signature]

        Ericson Aparecido Marino

        Officer

 

WITNESSES:

 

	
        [Signature]

        Carlos Leandro Aurélio
	
        [Signature]

        Luis Roberto de Medeiros

 

 

    
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[Signatures]
[circular stamp] Amyris Legal

    

    

 

 

 

    
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[Signatures]
[circular stamp] Amyris Legal

    

    

 

 

 

 

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[Signatures]

[circular stamp] Amyris LegalExhibit 10.41

 

 

SECOND AMENDMENT TO THE
LEASE AGREEMENT AND OTHER ARRANGEMENTS

 

Under this agreement, and in the best form of
law,

 

SÃO MARTINHO S.A., company
with registered office in the city of Pradópolis, State of São Paulo, at Fazenda São Martinho, CEP
014850-000, registered with the Taxpayers’ Registry of the Ministry of Finance under no. CNPJ/MF 51.466.860/0001-56, herein
represented under the terms in its By-Laws, hereinafter referred to as “LESSOR”, or “São Martinho”;

 

SMA INDÚSTRIA QUÍMICA S.A.,
company with registered office in the city of Pradópolis, State of São
Paulo, at Fazenda São Martinho, CEP 014850-000, registered with the Taxpayers’ Registry of the Ministry of Finance
under no. CNPJ/MF 12.065.083/0001-86, herein represented under the terms in its By-Laws, hereinafter referred to as “LESSEE”,
or, “SMA Indústria”;

 

And, as Intervening Parties and Guarantors:

 

AMYRIS BRASIL LTDA., limited
liability company, with registered office at Rua James Clerk Maxwell, 315, Techno Park, in the city of Campinas, State of
São Paulo, Brazil, registered with the Taxpayers’ Registry of the Ministry of Finance under no. CNPJ/MF 09.397.224/0001-20,
herein represented under the terms in its By-Laws (hereinafter referred to as “Amyris Brasil”);

 

AMYRIS INC., company
duly incorporated and existing under the laws of the State of Delaware, United States of America, with registered office at 5885
Hollis Street, Suite 100, Emeryville, State of California, United States of America, herein represented under the terms in its
By-Laws (hereinafter referred to as “ABI” and jointly with Amyris Brasil “Amyris”).

 

(Lessor and Lessee hereinafter referred jointly
as “Parties” or, separately as “Party”).

 

Whereas:

 

(i)  
São Martinho, Amyris Brasil and ABI have created a Joint Venture (“JV”), aiming to build and
operate the first plant in Brazil for production of renewable products with Amyris technology;

 

(ii)   São
Martinho and Amyris have created the JV under the name SMA Indústria;

 

(iii) Under the
JV, São Martinho and SMA Indústria have executed on May 1, 2010 the Lease Agreement and Other Arrangements (“Agreement”),
related to the lease of a property owned by São Martinho where the registered office of SMA Indústria (“Property”)
was located, amended on February 1, 2011 (“First Amendment”);

 

 

 

 

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(iv)  São Martinho
and Amyris have terminated the JV, and Amyris Brasil has agreed upon acquiring from São Martinho its share in SMA Indústria,
under the terms in the Share Purchase and Sale Agreement, executed also on this date (“SPA”); and

 

(v)  Under
the terms in the SPA, the Parties and Amyris have agreed upon altering the term of the lease of the Property for twelve
(12) months from the date of transfer of the shares of SMA Indústria held by São Martinho to Amyris Brasil (“Closure
Date”), as result of Amyris obligation to transfer all assets, equipment, material, machinery, or other assets used or held
by SMA (“Assets”) to another location by such term, except the foundation of the plant located in the Property that
will remain at the site.

 

The Parties agree, and under the terms of
current laws, upon executing the Second Amendment to the Lease Agreement and Other Arrangements (“Second Amendment”),
under the following terms and conditions:

 

1.            The Parties choose to amend the term of the Agreement agreed upon in the First Amendment (namely, 20 years from
the date of signature of the First Amendment, that is, February 1, 2031) to twelve (12) months from the Closure Date.

 

1.1.         
The Parties agree that the LESSEE may be entitled to terminate the Agreement early should the transfer of assets
be concluded before the twelve (12)-month term, with no penalties.

 

1.1.1. In case of
early termination of the Agreement by the LESSEE, under the terms in clause 1.1 above, the LESSEE shall remain responsible
for rents and ordinary expenses (like power, water, taxes, telephone, etc.) until acceptance of the keys by the LESSOR.

 

1.2.         
For avoidance of doubts, the Property is to be delivered by the LESSEE to the LESSOR free of any people and
goods (except for the foundations), under perfect use conditions, except for regular wear and tear.

 

2.            
The LESSEE and Amyris hereby agree upon arranging the removal of all the machinery, equipment, and other assets
from the Property prior to the termination of the new term of this agreement.

 

2.1.          
If, following termination of the twelve
(12)-month term from the Closure Date, the LESSOR finds that the Property is not fully
free of goods and people, the LESSOR may, at its sole discretion, adopt all measures needed to complete vacate the
Property, disposing materials, equipment and/or other assets that are located in the Property as deemed to be appropriate and charging
from the LESSEE all costs and expenses required for such disposal, without prejudice to the terms in item 3 below.

 

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3.           
Should the LESSEE delay the delivery of the Property free of assets
or people, the LESSEE shall pay to the LESSOR a fine of R$ 1,500.00 (one thousand and five hundred reais) per late
day, without prejudice of appropriate legal measures to safeguard the rights of the LESSOR and the amounts corresponding
to the lease and ordinary expenses of the Property that are still due by the LESSEE.

 

4.           
During the lease and until effective vacancy of the Property, the LESSEE shall remain responsible for the payment
of rents and ordinary consumption expenses like water, power, telephone, taxes; and such obligations hall be terminated on the
date the Property is returned to the LESSOR.

 

5.           
Amyris Brasil and ABI execute this Second Amendment as intervening parties and solidary guarantors of the LESSEE
obligations set forth in this agreement, including without limitation the payment of rents, ordinary consumption expenses, fine
set forth under the terms in item 3 above.

 

6.            Notwithstanding any term otherwise in this Agreement, neither Party, their affiliates and/or employees or representatives
shall be liable before the other Party for any indirect damage or loss of profit.

 

7.            
Amyris Brasil and ABI hereby represent to be aware and agree upon the terms and conditions of the Lease Agreement and
the first amendment, as well as with all obligations set forth hereunder and in the Lease Agreement and the first amendment, being
jointly responsible with the LESSEE.

 

8. 
All other terms in the Agreement and the First Amendment that have not been expressly amended by this Second Amendment
and that are not in conflict with the terms hereunder shall remain unchanged, and shall be part of the amended agreement, for all
legal purposes.

 

In witness whereof, the Parties sign this
Agreement in four (4) counterparts of equal tenor and form, before two witnesses, to produce all legal effects.

 

São Paulo, August 31, 2015

 

LESSOR:

 

	 	[Signature]	 	[Signature]	 
	 	[illegible]	SÃO MARTINHO S.A.	[illegible]	 

 

LESSEE:

 

	 	[Signature]	 	[Signature]	 
	 	 	SMA INDÚSTRIA QUÍMICA S.A.	[illegible] 	 

 

 

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INTERVENING PARTIES:

 

	 	/s/ Erica Baumgarten	 	/s/ Giani Ming Valent	 
	 	AMYRIS BRASIL LTDA	 

 

 

	 	 	/s/ John Melo	 	 
	 	AMYRIS INC.	 

 

Witnesses:

 

	
        1. [Signature]

        Name: Mayara Muniz de Freitas
	
        2. [Signature]

        Name: Mariana Muniz Giaccio

        

 

 

 

 

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