Document:

EX-10.1

 Exhibit 10.1 

BIO-TECHNE CORPORATION 

2014 EMPLOYEE STOCK PURCHASE PLAN 

ARTICLE I - ESTABLISHMENT OF PLAN 
  

	1.01	Adoption by Board of Directors. By action of the Board of Directors of Bio-Techne Corporation, (the “Corporation”) on September 8, 2014, subject to approval by its shareholders, the
Corporation has adopted an employee stock purchase plan pursuant to which Eligible Employees of the Corporation and certain of its Subsidiaries may be offered the opportunity to purchase shares of Stock of the Corporation. The terms and conditions
of this Plan are set forth in this plan document, as amended from time to time as provided herein. The Corporation intends that the Plan shall qualify as an “employee stock purchase plan” under Section 423 of the Internal Revenue Code
of 1986, as amended from time to time (the “Code”), and shall be construed in a manner consistent with the requirements of Code Section 423 and the regulations thereunder. 

 

	1.02	Shareholder Approval and Term. This Plan shall become effective upon its adoption by the Board of Directors and shall terminate December 31, 2024; provided, however, that the Plan shall be subject to
approval by the shareholders of the Corporation within twelve (12) months after the Plan is adopted by the Board in the manner provided under Code Section 423 and the regulations thereunder; and provided, further that the Board of
Directors may extend the term of the Plan for such period as the Board, in its sole discretion, deems advisable. In the event the shareholders fail to approve the Plan within twelve (12) months after the Plan is adopted by the Board, this Plan
shall not become effective and shall have no force and effect, participation in the Plan shall immediately cease, all outstanding options shall immediately be canceled and all payroll deductions shall be returned to the Participants without
interest. No shares of stock shall be issued to any Participant for any Phase unless and until the shareholders approve the Plan within such twelve-month period. 

ARTICLE II - PURPOSE 
  

	2.01	Purpose. The primary purpose of the Plan is to provide an opportunity for Eligible Employees of the Corporation to become shareholders of the Corporation, thereby providing them with an incentive to remain in the
Corporation’s employ, to improve operations, to increase profits and to contribute more significantly to the Corporation’s success. 

  
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 ARTICLE III - DEFINITIONS 

 

	3.01	“Administrator” means the Board of Directors or such Committee appointed by the Board of Directors to administer the Plan. The Board or the Committee may, in its sole discretion, authorize the officers
of the Corporation to carry out the day-to-day operation of the Plan. In its sole discretion, the Board may take such actions as may be taken by the Administrator, in addition to those powers expressly reserved to the Board under this Plan.

  

	3.02	“Board of Directors” or “Board” means the Board of Directors of Bio-Techne Corporation. 

  

	3.03	“Compensation” means the Participant’s base compensation, excluding overtime, commissions, bonuses and tips. 

  

	3.04	“Corporation” means Bio-Techne Corporation, a Minnesota corporation. 

  

	3.05	“Eligible Employee” means any employee who, as determined on or immediately prior to an Enrollment Period, is a full-time or part-time employee of the Corporation or one of its Subsidiaries, is
customarily employed for more than twenty (20) hours per week, and has completed at least six (6) months of continuous service; provided, however, that employees who are officers subject to Section 16 of the Securities Exchange Act of
1934 shall not participate. 

  

	3.06	“Enrollment Period” means the period determined by the Administrator for purposes of accepting elections to participate during a Phase from Eligible Employees. 

 

	3.07	“Fiscal Year” means the fiscal year of the Corporation, which is the twelve-month period ending June 30th. 

 

	3.08	“Participant” means an Eligible Employee who has been granted an option and is participating during a Phase through payroll deductions, but shall exclude those employees subject to the limitations
described in Section 9.03 below. 

  

	3.09	“Phase” means the period beginning on the date that the option was granted, otherwise referred to as the commencement date of the Phase, and ending on the date that the option was exercised, otherwise
referred to as the termination date of the Phase. 

  

	3.10	“Plan” means the Bio-Techne Corporation 2014 Employee Stock Purchase Plan. 

  

	3.11	“Stock” means the voting common stock of the Corporation. 

  

	3.12	“Subsidiary” means any corporation defined as a subsidiary of the Corporation in Code Section 424(f) as of the effective date of the Plan and that the Board has approved to participate in the Plan,
and such other corporations that qualify as subsidiaries of the Corporation under Code Section 424(f) as the Board approves to participate in this Plan from time to time. 

  
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 ARTICLE IV - ADMINISTRATION 

 

	4.01	Administration. Except for those matters expressly reserved to the Board pursuant to any provisions of the Plan, the Administrator shall have full responsibility for administration of the Plan, which
responsibility shall include, but shall not be limited to, the following: 

  

	 	(a)	The Administrator shall, subject to the provisions of the Plan, establish, adopt and revise such rules and procedures for administering the Plan, and shall make all other determinations as it may deem necessary or
advisable for the administration of the Plan; 

  

	 	(b)	The Administrator shall, subject to the provisions of the Plan, determine all terms and conditions that shall apply to the grant and exercise of options under this Plan, including, but not limited to, the number of
shares of Stock that may be granted, the date of grant, the exercise price and the manner of exercise of an option. The Administrator may, in its discretion, consider the recommendations of the management of the Corporation when determining such
terms and conditions; 

  

	 	(c)	The Administrator shall have the exclusive authority to interpret the provisions of the Plan, and each such interpretation or determination shall be conclusive and binding for all purposes and on all persons, including,
but not limited to, the Corporation and its Subsidiaries, the shareholders of the Corporation and its Subsidiaries, the Administrator, the directors, officers and employees of the Corporation and its Subsidiaries, and the Participants and the
respective successors-in-interest of all of the foregoing; and 

  

	 	(d)	The Administrator shall keep minutes of its meetings or other written records of its decisions regarding the Plan and shall, upon requests, provide copies to the Board. 

ARTICLE V - PHASES OF THE PLAN 
  

	5.01	Phases. The Plan shall be carried out in one or more Phases of six (6) months each. Unless otherwise determined by the Administrator, in its discretion, Phases shall commence on January 1 and
July 1 of each fiscal year during the term of the Plan. No two Phases shall run concurrently, and no Phase shall be for a period longer than twenty-seven (27) months. 

  
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	5.02	Limitations. The Administrator may, in its discretion, limit the number of shares available for option grants during any Phase as it deems appropriate. Without limiting the foregoing, in the event all of the
shares of Stock reserved for the grant of options under Section 12.01 is issued pursuant to the terms hereof prior to the commencement of one or more Phases or the number of shares of Stock remaining is so small, in the opinion of the
Administrator, as to render administration of any succeeding Phase impracticable, such Phase or Phases may be canceled or the number of shares of Stock limited as provided herein. In addition, if, based on the payroll deductions authorized by
Participants at the beginning of a Phase, the Administrator determines that the number of shares of Stock which would be purchased at the end of a Phase exceeds the number of shares of Stock remaining reserved under Section 12.01 hereof for
issuance under the Plan, or if the number of shares of Stock for which options are to be granted exceeds the number of shares designated for option grants by the Administrator for such Phase, then the Administrator shall make a pro rata allocation
of the shares of Stock remaining available in as nearly uniform and equitable a manner as the Administrator shall consider practicable as of the commencement date of the Phase or, if the Administrator so elects, as of the termination date of the
Phase. In the event such allocation is made as of the commencement date of a Phase, the payroll deductions which otherwise would have been made on behalf of Participants shall be reduced accordingly. 

ARTICLE VI - ELIGIBILITY 
  

	6.01	Eligibility. Subject to the limitations described in Section 9.03, each employee who is an Eligible Employee on or immediately prior to the commencement of a Phase shall be eligible to participate in such
Phase. If, in the discretion of the Administrator, any Phase commences on a date other than January 1 or July 1, whether an employee is an Eligible Employee shall be determined on a date selected by the Administrator, which date shall be
at least thirty (30) days prior to the commencement date of the Phase. 

 ARTICLE VII - PARTICIPATION 

 

	7.01	Participation. Participation in the Plan is voluntary. An Eligible Employee who desires to participate in any Phase of the Plan must complete the Plan enrollment form provided by the Administrator and deliver
such form to the Administrator or its designated representative during the Enrollment Period established by the Administrator prior to the commencement date of the Phase. 

  
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	7.02	Subsequent Phases. An Eligible Employee who elects to participate in a Phase of a fiscal year shall be deemed to have elected to participate in each subsequent Phase unless such Participant elects to discontinue
payroll deductions during a Phase or exercises his or her right to withdraw amounts previously withheld as provided in Article X hereof. In such event, such Participant must complete a change of election form or a new Plan enrollment form and file
such form with the Administrator during the Enrollment Period prior to the next Phase with respect to which the Eligible Employee wishes to participate. 

ARTICLE VIII - PAYMENT: PAYROLL DEDUCTIONS 
  

	8.01	Enrollment. Each Eligible Employee electing to participate shall indicate such election on the Plan enrollment form and designate therein a percentage or dollar amount of such Participant’s Compensation
during each pay period during the Phase. Subject to the Participant’s right to discontinue or withdraw payroll deductions as provided in Section 10.01, such percentage or dollar amount shall be at least equal to such minimum percentage or
dollar amount as the Administrator may establish from time to time; provided, however, that a Participant’s payroll deduction for any pay period during the Phase shall not exceed $950 or such other dollar amount as the Administrator may
establish from time to time. In order to be effective, such Plan enrollment form must be properly completed and received by the Administrator by the due date indicated on such form, or by such other date established by the Administrator.

  

	8.02	Payroll Deductions. Payroll deductions for a Participant shall commence with the paycheck issued immediately after the commencement date of the Phase and shall terminate with the paycheck issued immediately prior
to the termination date of that Phase, unless the Participant elects to discontinue payroll deductions or exercises his or her right to withdraw all accumulated payroll deductions previously withheld during the Phase as provided in Article X hereof.
The authorized payroll deductions shall be made on an after-tax basis over the pay periods of such Phase by deducting from the Participant’s Compensation for each such pay period that amount specified by the Participant in the Plan enrollment
form. 

 Unless the Participant elected to discontinue payroll deductions or exercised his or her right to withdraw all
accumulated payroll deductions previously withheld during the preceding Phase (in which event the Participant must complete a change of election form or a new Plan enrollment form, as the case may be, to continue participation for any subsequent
Phase), the Corporation shall continue to withhold from such Participant’s Compensation the same designated percentage or designated amount specified by the Participant in the most recent Plan enrollment form previously completed by the
Participant for all subsequent Phases; provided, however, that the Participant may, if he or she so chooses, increase, decrease or discontinue payroll deductions for any or all such subsequent Phases by properly completing a change of election form
during the Enrollment Period for such subsequent Phase and delivering such form to the Administrator by the due date for receipt of such forms for that Phase. 

  
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	8.03	Change in Compensation During a Phase. In the event that the Participant’s Compensation is increased or decreased during a Phase for any reason so that the amount actually withheld on behalf of the
Participant as of the termination date of the Phase is different from the amount anticipated to be withheld as determined on the commencement date of the Phase, then the extent to which the Participant may exercise his or her option shall be based
on the amounts actually withheld on his or her behalf, subject to the limitations in Article IX. In the event of a change in the pay period of any Participant, such as from biweekly to monthly, an appropriate adjustment shall be made to the
deduction in each new pay period so as to insure the deduction of the proper amount authorized by the Participant. 

  

	8.04	Decreases During a Phase. In addition to the right to discontinue or withdraw payroll deductions during a Phase as provided in Article X, a Participant may decrease the amount of Compensation designated to be
deducted as payroll deductions during a Phase (but not below the minimum percentage or minimum amount specified by the Administrator) by completing and filing such forms as the Administrator may require. Such decrease shall be effective with the
next payroll period beginning after the date that the Administrator receives such forms and shall apply to all remaining Compensation paid during the Phase. The Participant may exercise the right to decrease his or her payroll deductions only once
during each Phase. 

 ARTICLE IX - PURCHASE OF STOCK 

 

	9.01	Grant of Option. Subject to Article X, a Participant who has elected to participate in the manner described in Article VIII and who is employed by the Corporation or a Subsidiary as of the commencement date of a
Phase shall be granted an option as of such date to purchase that number of whole shares of Stock determined by dividing the total amount to be credited to the Participant’s account by the closing price for a share of the Corporation’s
Stock as reported on the Nasdaq Stock Market or on an established securities exchange as of the commencement date of the Phase. The purchase price per share for such Stock shall be determined under Section 9.02 hereof, and the number of shares
exercisable shall be determined under Section 9.03 hereof. 

  

	9.02	Purchase Price. Subject to the limitations hereinbelow, the purchase price for such Stock shall equal eighty-five percent (85%) of the closing price for a share of the Corporation’s Stock as reported on
the Nasdaq Stock Market or on an established securities exchange as of the termination date of the Phase. 

  
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 In the event that the commencement or termination date of a Phase is a Saturday, Sunday or
holiday, the amounts determined under the foregoing subsections shall be determined using the price as of the last preceding trading day. 

If the Corporation’s Stock is not listed on the Nasdaq Stock Market or on an established securities exchange, then the option price
shall equal eighty-five percent (85%) of the fair market value of such stock as of the termination date of the Phase. Such “fair market value” shall be determined by the Board. 

 

	9.03	Limitations. No employee shall be granted an option hereunder: 

 (a) Which permits his
or her rights to purchase Stock under all employee stock purchase plans of the Corporation or its Subsidiaries to accrue at a rate which exceeds Twenty-Five Thousand Dollars ($25,000) of fair market value of such Stock (determined at the time such
option is granted) for each calendar year in which such option is outstanding at any time; 
 (b) If such employee would own and/or hold,
immediately after the grant of the option, Stock possessing five percent (5%) or more of the total combined voting power or value of all classes of stock of the Corporation or of any Subsidiary. For purposes of determining stock ownership under
this paragraph, the rules of Section 424(d) of the Code and the regulations thereunder shall apply. 
 (c) Which, if exercised, would
cause the limits established by the Administrator under Section 5.02 to be exceeded. 
  

	9.04	Exercise of Option. Subject to a Participant’s right to withdraw in the manner provided in Section 10.01, a Participant’s option for the purchase of shares of Stock will be exercised automatically
on the termination date of that Phase. However, in no event shall a Participant be allowed to exercise an option for more shares of Stock than can be purchased with the payroll deductions accumulated by the Participant in his or her bookkeeping
account during such Phase. 

  

	9.05	Delivery of Shares. As promptly as practicable after the termination of any Phase, the Corporation’s transfer agent or other authorized representative shall reflect the issuance of shares on the
Corporation’s stock transfer books of that number of whole shares of Stock purchased upon the exercise of the Participant’s option, and effect the issuance of such shares of Stock to the Participant via book entry or stock certificate. The
Corporation may, in its sole discretion, arrange with the Corporation’s transfer agent or other authorized representative to establish, at the direction of the Participant, individual securities accounts to which will be credited that number of
whole shares of Stock that are purchased upon such exercise, such securities account to be subject to such terms and conditions as may be imposed by the transfer agent or authorized representative. 

  
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 The shares of the Corporation’s Stock to be delivered to a Participant pursuant to the
exercise of an option under Section 9.04 of the Plan will be registered in the name of the Participant or, if the Participant so directs by written notice to the Administrator prior to the termination date of the Phase, in the names of the
Participant and one other person the Participant may designate as his joint tenant with rights of survivorship, to the extent permitted by law. 

Any accumulated payroll deductions remaining after the exercise of the Participant’s option shall be returned to the Participant,
without interest, on the first paycheck issued for the payroll period which begins on or immediately after the commencement date of next Phase; provided, however, that the Corporation may, under rules of uniform application, retain such remaining
amount in the Participant’s bookkeeping account and apply it toward the purchase of shares of Stock in the next succeeding Phase, unless the Participant requests a withdrawal of such amount pursuant to Section 10.01. 

 

	9.06	Transfer Restrictions. A Participant who has acquired shares of Stock of the Corporation through the exercise of his or her option pursuant to Section 9.04 (or in the case of death, such Participant’s
estate) shall not sell, assign, give, bequest or otherwise transfer or dispose of such Stock until the six-month anniversary of the date on which the shares were issued to the Participant. Notwithstanding the preceding sentence, the Administrator
may require that the Participant not transfer such shares for any additional period determined by the Administrator to be necessary to ensure that the Corporation is able to meet its reporting requirements pursuant to Code Section 423 and the
regulations thereunder. 

 Any attempt by the Participant to sell or transfer such shares in violation of this
Section 9.06 shall be considered null and void and of no force or effect. During such restricted transfer period, each certificate and book entry evidencing such shares shall bear an appropriate legend or stop transfer order, respectively,
referring to the terms, restrictions and conditions applicable to the transfer of such shares; provided, however, that failure to so endorse any of such stock certificates or book entry shall not render invalid or inapplicable this
Section 9.06. The Corporation shall keep a copy of the Plan available for inspection by all Participants at its registered office. 

ARTICLE X - WITHDRAWAL OR 

DISCONTINUATION OF PAYROLL WITHHOLDINGS 
  

	10.01	 Withdrawal. At any time during the Phase, a Participant may request a withdrawal of all accumulated payroll deductions then credited to the
Participant’s bookkeeping account by completing a change of election form and filing such form with the Administrator. The Participant’s request shall be effective as of the beginning of the next payroll period immediately following the
date that the Administrator receives the Participant’s properly completed change of election form. As soon as administratively feasible after such payroll period, all payroll deductions credited to

  
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a bookkeeping account for the Participant will be paid to such Participant, without interest, and no further payroll deductions will be made during that Phase or, unless the Participant completes
a new Plan enrollment form as provided in Section 8.02 above, any future Phase. If the Participant requests a withdrawal, the option granted to the Participant under that Phase of the Plan shall immediately lapse and shall not be exercisable.
Partial withdrawals of payroll deductions are not permitted. 

 Notwithstanding the foregoing, in order to be effective for a
particular Phase, the Participant’s request for withdrawal must be properly completed and received by the Administrator on or before the date established by the Administrator. Requests for withdrawal that are received after that due date shall
not be effective and no withdrawal shall be made, unless otherwise determined by the Administrator. 
  

	10.02	Discontinuation. At any time during the Phase, a Participant may request that the Administrator discontinue any further payroll deductions that would otherwise be made during the remainder of the Phase by
completing a change of election form and filing such form with the Administrator at least thirty (30) days prior to the termination date of the Phase, or on or before such other date established by the Administrator. The Participant’s
request shall be effective as of the beginning of the next payroll period immediately following the date that the Administrator receives the Participant’s properly completed change of election form. Upon the effective date of the
Participant’s request, the Corporation will discontinue making payroll deductions for such Participant for that Phase, and all future Phases, unless the Participant completes another change of election form as provided above. 

ARTICLE XI - TERMINATION OF EMPLOYMENT 
  

	11.01	Termination. If, on or before the termination date of any Phase, a Participant’s employment terminates with the Corporation for any reason, voluntarily or involuntarily, including by reason of retirement,
disability or death, the payroll deductions credited to such Participant’s bookkeeping account for such Phase, if any, will be returned to the Participant, without interest, and any options granted to such Participant under the Plan shall
immediately lapse and shall not be exercisable. The return of such payroll deductions shall be made to the Participant as soon as administratively practicable following the Participant’s termination of employment. In the event that such
termination occurs near the end of a Phase and the Corporation is unable to discontinue payroll deductions for such Participant for his or her final paycheck(s), such deductions shall still be made but shall be returned to the Participant as
provided herein. In no event shall the accumulated payroll deductions be used to purchase any shares of Stock. 

 If the
option lapses as a result of the Participant’s death, any accumulated payroll deductions credited to the Participant’s bookkeeping account will be paid to the Participant’s estate, without interest. In the event a Participant dies
after exercise of the Participant’s option but prior to delivery of the Stock to be transferred pursuant to the exercise of the option under Section 9.04 above, any such Stock and/or accumulated payroll deductions remaining after such
exercise shall be delivered and/or paid by the Corporation to the Participant’s estate. 

  
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 The Corporation will not be responsible for or be required to give effect to the disposition of
any cash or Stock or the exercise of any option in accordance with any will or other testamentary disposition made by such Participant or in accordance with the provisions of any law concerning intestacy, or otherwise. No person shall, prior to the
death of a Participant, acquire any interest in any Stock, in any option or in the cash credited to the Participant’s bookkeeping account during any Phase of the Plan. 
  

	11.02	Subsidiaries. In the event that any Subsidiary ceases to be a Subsidiary of the Corporation, the employees of such Subsidiary shall be considered to have terminated their employment for purposes of
Section 11.01 hereof as of the date the Subsidiary ceased to be a Subsidiary of the Corporation. 

 ARTICLE XII - STOCK
RESERVED FOR OPTIONS 
  

	12.01	Shares Reserved. Two Hundred Thousand (200,000) shares of Stock, which may be authorized but unissued shares of the Corporation, or the number and kind of securities to which said 200,000 shares may be
adjusted in accordance with Section 14.01 hereof, are reserved for issuance upon the exercise of options to be granted under the Plan. Shares subject to the unexercised portion of any lapsed or expired option may again be subject to option
under the Plan. 

  

	12.02	Rights as Shareholder. The Participant shall have no rights as a shareholder with respect to any shares of Stock subject to the Participant’s option until the date the issuance is reflected on the
Corporation’s stock transfer books and the shares are issued to Participant as provided in Section 9.05. No adjustment shall be made for dividends (ordinary or extraordinary, whether in cash, securities or other property), distributions or
other rights for which the record date is prior to the date such issuance occurs, except as otherwise provided in Section 14.01 hereof. 

ARTICLE XIII - ACCOUNTING AND USE OF FUNDS 
  

	13.01	Bookkeeping Account. Payroll deductions for Participants shall be credited to bookkeeping accounts established by the Corporation for each such Participant under the Plan. A Participant may not make any cash
payments into such account. Such account shall be solely for bookkeeping purposes and shall not require the Corporation to establish any separate fund or trust hereunder. All funds from payroll deductions received or held by the Corporation under
the Plan may be used, without limitation, for any corporate purpose by the Corporation, which shall not be obligated to segregate such funds from its other funds. In no event shall Participants be entitled to interest on the amounts credited to such
bookkeeping accounts. 

  
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 ARTICLE XIV - ADJUSTMENT PROVISION 

 

	14.01	General. Subject to any required action by the shareholders of the Corporation, in the event of an increase or decrease in the number of outstanding shares of Stock or in the event the Stock is changed into or
exchanged for a different number or kind of shares of stock or other securities of the Corporation or another corporation by reason of a reorganization, merger, consolidation, divestiture (including a spin-off), liquidation, recapitalization,
reclassification, stock dividend, stock split, combination of shares, rights offering or any other change in the corporate structure or shares of the Corporation, the Board (or, if the Corporation is not the surviving corporation in any such
transaction, the board of directors of the surviving corporation), in its sole discretion, may adjust the number and kind of securities subject to and reserved under the Plan and, to prevent the dilution or enlargement of rights of those Eligible
Employees to whom options have been granted, may adjust the number and kind of securities subject to such outstanding options and, where applicable, the exercise price per share for such securities. 

In the event of sale by the Corporation of substantially all of its assets and the consequent discontinuance of its business, or in the event
of a merger, exchange, consolidation, reorganization, divestiture (including a spin-off), liquidation, reclassification or extraordinary dividend (collectively referred to as a “transaction”), after which the Corporation is not the
surviving corporation, the Board may, in its sole discretion, at the time of adoption of the plan for such transaction, provide for one or more of the following: 
  

	 	(a)	The acceleration of the exercisability of outstanding options granted at the commencement of the Phase then in effect, to the extent of the accumulated payroll deductions made as of the date of such acceleration
pursuant to Article VIII hereof; 

  

	 	(b)	The complete termination of this Plan and a refund of amounts credited to the Participants’ bookkeeping accounts hereunder; or 

 

	 	(c)	The continuance of the Plan only with respect to completion of the then current Phase and the exercise of options thereunder. In the event of such continuance, Participants shall have the right to exercise their options
as to an equivalent number of shares of stock of the corporation succeeding the Corporation by reason of such transaction. 

In the event of a transaction where the Corporation survives, then the Plan shall continue in effect, unless the Board takes one or more of
the actions set forth above. 

  
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The grant of an option pursuant to the Plan shall not limit in any way the right or power of the Corporation to make adjustments, reclassifications, reorganizations or changes in its capital or
business structure or to merge, exchange or consolidate or to dissolve, liquidate, sell or transfer all or any part of its business or assets. 

ARTICLE XV - NONTRANSFERABILITY OF OPTIONS 
  

	15.01	Nontransferability. Options granted under any Phase of the Plan shall not be transferable and shall be exercisable only by the Participant during the Participant’s lifetime. 

 

	15.02	Nonalienation. Neither payroll deductions granted to a Participant’s account, nor any rights with regard to the exercise of an option or to receive Stock under any Phase of the Plan may be assigned,
transferred, pledged or otherwise disposed of in any way by the Participant. Any such attempted assignment, transfer, pledge or other disposition shall be null and void and without effect, except that the Corporation may, at its option, treat such
act as an election to withdraw in accordance with Section 10.01. 

 ARTICLE XVI - AMENDMENT AND TERMINATION 

 

	16.01	General. The Plan may be terminated at any time by the Board of Directors, provided that, except as permitted in Section 14.01 hereof, no such termination shall take effect with respect to any options then
outstanding. The Board may, from time to time, amend the Plan as it may deem proper and in the best interests of the Corporation or as may be necessary to comply with Code Section 423, as amended, and the regulations thereunder, or other
applicable laws or regulations; provided, however, no such amendment shall, without the consent of a Participant, materially adversely affect or impair the right of a Participant with respect to any outstanding option; and provided, further, that no
such amendment shall: 

  

	 	(a)	increase the total number of shares for which options may be granted under the Plan (except as provided in Section 14.01 herein); 

 

	 	(b)	modify the group of Subsidiaries whose employees may be eligible to participate in the Plan or materially modify any other requirements as to eligibility for participation in the Plan; or 

 

	 	(c)	materially increase the benefits accruing to Participants under the Plan; 

 without the
approval of the Corporation’s shareholders, if such approval is required for compliance with Code Section 423, as amended, and the regulations thereunder, or other applicable laws or regulations. 

  
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 Further, the Administrator may, in its discretion (i) amend the Plan to comply with the
laws in other countries in which the Corporation and its Subsidiaries operate or have Participants, (ii) modify the terms and conditions of the Plan with respect to Participants who reside outside of the United States to comply with applicable
foreign laws, (iii) establish sub-plans, and (iv) take any action deemed advisable to comply with any necessary local governmental regulatory exemptions or approvals; provided, however, that no action may be taken that would violate any
securities law, tax law or any other applicable law or cause the Plan not to comply with Code Section 423. 
 ARTICLE XVII - NOTICES

  

	17.01	General. All notices, forms, elections or other communications in connection with the Plan or any Phase thereof shall be in such form as specified by the Corporation or the Administrator from time to time, and
shall be deemed to have been duly given when received by the Participant or his or her personal representative or by the Corporation or its designated representative, as the case may be. 

  
 - 13 -Exhibit 10.1

 

BRAINSTORM CELL
THERAPEUTICS INC.

 

Incentive Stock Option Agreement

Granted Under 2014 Stock Incentive Plan

 

		1.	Grant of Option.

 

This agreement evidences the grant by Brainstorm
Cell Therapeutics Inc., a Delaware corporation (the “Company”), on         ,
201[    ] (the “Grant Date”) to [                    ],
an employee of the Company (the “Participant”), of an option to purchase, in whole or in part, on the terms provided
herein and in the Company’s 2014 Stock Incentive Plan (the “Plan”), a total of [            ]
shares (the “Shares”) of common stock, $0.00005 par value per share, of the Company (“Common Stock”) at
$[        ] per Share. Unless earlier terminated, this option shall expire at 5:00 p.m.,
Eastern time, on [                    ]
(the “Final Exercise Date”).

 

It is intended that the option evidenced
by this agreement shall be an incentive stock option as defined in Section 422 of the Internal Revenue Code of 1986, as amended,
and any regulations promulgated thereunder (the “Code”). Except as otherwise indicated by the context, the term “Participant”,
as used in this option, shall be deemed to include any person who acquires the right to exercise this option validly under its
terms.

 

		2.	Vesting Schedule.

 

This option will become exercisable (“vest”)
as to                     .

 

The right of exercise shall be cumulative
so that to the extent the option is not exercised in any period to the maximum extent permissible it shall continue to be exercisable,
in whole or in part, with respect to all Shares for which it is vested until the earlier of the Final Exercise Date or the termination
of this option under Section 3 hereof or the Plan.

 

		3.	Exercise of Option.

 

(a) Form of Exercise. Each
election to exercise this option shall be in writing, signed by the Participant, and received by the Company at its principal office,
accompanied by this agreement, and payment in full in the manner provided in the Plan. The Participant may purchase less than the
number of shares covered hereby, provided that no partial exercise of this option may be for any fractional share.

 

(b) Continuous Relationship with
the Company Required. Except as otherwise provided in this Section 3, this option may not be exercised unless the Participant,
at the time he or she exercises this option, is, and has been at all times since the Grant Date, an employee or officer or director
of, or consultant or advisor (as such terms are defined and interpreted for purposes of Form S-8 under the Securities Act of 1933,
as amended) to, the Company or any parent or subsidiary of the Company as defined in Section 424(e) or (f) of the Code
(an “Eligible Participant”).

 

(c) Termination of Relationship
with the Company. If the Participant ceases to be an Eligible Participant for any reason, then, except as provided in paragraphs (d)
and (e) below, the right to exercise this option shall terminate three months after such cessation (but in no event after
the Final Exercise Date), provided that this option shall be exercisable only to the extent that the
Participant was entitled to exercise this option on the date of such cessation. Notwithstanding the foregoing, if the Participant,
prior to the Final Exercise Date, violates the non-competition or confidentiality provisions of any employment contract, confidentiality
and nondisclosure agreement or other agreement between the Participant and the Company, the right to exercise this option shall
terminate immediately upon such violation.

 

    	 

    	 

    

 

(d) Exercise Period Upon Death
or Disability. If the Participant dies or becomes disabled (within the meaning of Section 22(e)(3) of the Code) prior
to the Final Exercise Date while he or she is an Eligible Participant and the Company has not terminated such relationship for
“cause” as specified in paragraph (e) below, this option shall be exercisable, within the period of one year following
the date of death or disability of the Participant, by the Participant (or in the case of death by an authorized transferee), provided that this
option shall be exercisable only to the extent that this option was exercisable by the Participant on the date of his or her death
or disability, and further provided that this option shall not be exercisable after the Final Exercise Date.

 

(e) Termination for Cause.
If, prior to the Final Exercise Date, the Participant’s employment is terminated by the Company for Cause (as defined below),
the right to exercise this option shall terminate immediately upon the effective date of such termination of employment. If the
Participant is party to an employment or severance agreement with the Company that contains a definition of “cause”
for termination of employment, “Cause” shall have the meaning ascribed to such term in such agreement. Otherwise, “Cause”
shall mean willful misconduct by the Participant or willful failure by the Participant to perform his or her responsibilities to
the Company (including, without limitation, breach by the Participant of any provision of any employment, consulting, advisory,
nondisclosure, non-competition or other similar agreement between the Participant and the Company), as determined by the Company,
which determination shall be conclusive. The Participant shall be considered to have been discharged for Cause if the Company determines,
within 30 days after the Participant’s resignation, that discharge for cause was warranted.

 

		4.	Tax Matters.

 

(a) Withholding. No Shares
will be issued pursuant to the exercise of this option unless and until the Participant pays to the Company, or makes provision
satisfactory to the Company for payment of, any federal, state or local withholding taxes required by law to be withheld in respect
of this option.

 

(b) Disqualifying Disposition.
If the Participant disposes of Shares acquired upon exercise of this option within two years from the Grant Date or one year after
such Shares were acquired pursuant to exercise of this option, the Participant shall notify the Company in writing of such disposition.

 

		5.	Nontransferability of Option.

 

This option may not be sold, assigned,
transferred, pledged or otherwise encumbered by the Participant, either voluntarily or by operation of law, except by will or the
laws of descent and distribution, and, during the lifetime of the Participant, this option shall be exercisable only by the Participant.

 

		6.	Provisions of the Plan.

 

This option is subject to the provisions
of the Plan (including the provisions relating to amendments to the Plan), a copy of which is furnished to the Participant with
this option.

 

IN WITNESS WHEREOF, the Company has caused
this option to be executed under its corporate seal by its duly authorized officer. This option shall take effect as a sealed instrument.

 

	 	Brainstorm Cell Therapeutics Inc.
	 	 
	 	By:	 
	 	 	 
	 	Name:	 
	 	Title:	 

 

    	 

    	 

    

 

PARTICIPANT’S ACCEPTANCE

 

The undersigned hereby accepts the foregoing
option and agrees to the terms and conditions thereof. The undersigned hereby acknowledges receipt of a copy of the Company’s
2014 Stock Incentive Plan.

 

	 	PARTICIPANT:
	 	 
	 	 
	 	 
	 	Address:	 
	 	 	 
	 	 	 

 

    	 

    	 

    

 

FORM OF NOTICE OF STOCK OPTION EXERCISE

 

Date:

 

Brainstorm Cell Therapeutics Inc.

605 Third Avenue, 34th Floor

New York, NY 10158

Attention: Treasurer

 

Dear Sir or Madam:

 

I am the holder of an Incentive Stock Option
granted to me under the Brainstorm Cell Therapeutics Inc. (the “Company”) 2014 Stock Incentive Plan on                      for
the purchase of              shares of common stock,
par value $0.00005 per share, of the Company (“Common Stock”) at a purchase price of $         per
share.

 

I hereby exercise my option with respect
to              shares of Common Stock, for which
I have enclosed                      in
the amount of                     .
Please register my stock certificate as follows:

	 	 	 
	Name(s):	 	 
	 	 	 
	 	 	 
	 	 	 
	Address:	 	 
	 	 	 
	 	 	 
	 	 	 
	Tax I.D. #:	 	 

 

	Very truly yours,	 
	 	 
	 	 
	 	 
	Name:

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