Document:

EX-10.14

 Exhibit 10.14 
 SERIES E PREFERRED STOCK PURCHASE AGREEMENT 
 This Series
E Preferred Stock Purchase Agreement, dated as of November 20, 2013 (this “Agreement”), is entered into by and among Roka Bioscience, Inc., a Delaware corporation (the “Company”), and the several purchasers
named in Attachment 1 attached hereto (each a “Purchaser” and collectively, the “Purchasers”). 
 WHEREAS, the Company and certain investors named therein entered into a Series E Preferred Stock and Warrant Purchase Agreement on June 13, 2013 (the “Initial Series E Purchase
Agreement”), pursuant to which the Company sold and issued 17,111,567 shares of the Company’s Series E Preferred Stock, $0.001 par value per share (“Series E Preferred Stock”) for a purchase price of $1.461 per share
(the “Initial Price Per Share”) to certain investors (the “Previous Investors”); 
 WHEREAS,
the Company and the Previous Investors entered into an amendment to the Series E Purchase Agreement on November 20, 2013 (the “Amendment”), pursuant to which the purchase price per share of the Series E Preferred Stock was
reduced from the Initial Price to $1.275 per share of Series E Preferred Stock (the “Price Per Share”), and the Company issued 2,492,422 shares of the Series E Preferred Stock to the Previous Investors; 

WHEREAS, the Company desires to sell, and the Purchasers desire to purchase, additional shares of Series E Preferred Stock pursuant to
the terms of this Agreement (the “Additional Series E Financing”); and 
 NOW, THEREFORE, in consideration of
the mutual promises and covenants contained in this Agreement, the parties hereto agree as follows: 
 1. AUTHORIZATION AND SALE OF
SECURITIES. 
 1.1 Authorization. On or prior to the Closing Date (as defined below), the Company shall
have (a) duly authorized the sale and issuance, pursuant to the terms of this Agreement, of up to 13,330,711 shares of its Series E Preferred Stock to the Purchasers (collectively, the “Shares”) and the issuance of such shares
of Series A Common Stock of the Company, $0.001 par value per share (“Series A Common Stock”), to be issued upon conversion of the Shares (the “Conversion Shares”), each having the rights, restrictions, privileges
and preferences set forth in the Sixth Amended and Restated Certificate of Incorporation of the Company attached hereto as Exhibit A (the “Charter”), each having the rights, restrictions, privileges and preferences set forth
in the Charter; and (b) adopted and filed the Charter with the Secretary of State of the State of Delaware. 
 1.2
Sale of Shares. Subject to the terms and conditions of this Agreement, at each Closing (as defined below), the Company will sell and issue to each Purchaser, and each Purchaser agrees, severally and not jointly, to purchase from the
Company, the number of shares of Series E Preferred Stock set forth opposite such Purchaser’s name on Attachment 1 for a purchase price per share of Series E Preferred Stock equal to the Price Per Share, payable in cash by wire transfer
to an account designated by the Company. The Shares and the Conversion Shares shall be referred to collectively in this Agreement as the “Securities.” 

 2. THE CLOSING. 
 2.1 Closing. Subject to the satisfaction of all of the conditions set forth in Sections 5 and 6 hereof, the closing of the initial issuance and sale of the Shares shall be held
at the offices of Lowenstein Sandler LLP, 65 Livingston Avenue, Roseland, New Jersey 07068, at 12:00 p.m. Eastern Daylight Time on November 20, 2013 (the “Closing”), or at such later time or such other place as the Company and
the Purchasers acquiring a majority of the Shares (the “Required Purchasers”) hereto shall mutually agree. The date on which the Closing is actually held is referred to herein as the “Closing Date.” 

2.2 Delivery. At the Closing, subject to the terms and conditions hereof, in addition to the deliveries required pursuant
to Section 5 hereof, the Company will deliver to each Purchaser a certificate representing the number of Shares, against payment of the purchase price therefor. 
 2.3 Use of Proceeds. The proceeds from the sale of the Shares shall be used to fund the Company’s development and operations. 

3. REPRESENTATIONS AND WARRANTIES OF THE COMPANY. Subject to and except as disclosed by the Company in the schedules attached hereto specifically
identifying the relevant subparagraph(s) hereof (the “Disclosure Schedules”), the Company hereby represents and warrants to the Purchasers, as of the Closing unless otherwise specified, as follows: 

3.1 Organization and Standing. The Company is a corporation duly organized, validly existing and in good standing under the
laws of the State of Delaware and has full power and authority to own and operate, license or lease its properties, whether tangible or intangible, and conduct its business as currently conducted and as proposed to be conducted by it and to enter
into and perform this Agreement (including all schedules and exhibits hereto) and each of the other agreements required to be executed by the Company on or prior to the Closing pursuant to Section 5.1 hereof (the “Ancillary
Agreements”) and to carry out the transactions required to be executed by the Company contemplated by this Agreement and the Ancillary Agreements. The Company is duly qualified to do business as a foreign corporation and is in good standing
in every jurisdiction in which the failure to so qualify is reasonably likely to have a Material Adverse Effect. The Company has furnished to counsel to the Purchasers true and complete copies of the Charter and the Company’s By-Laws (the
“By-Laws”), each as amended to date and as presently in effect. 
 3.2 Authority for
Agreement. The execution, delivery and performance by the Company of this Agreement (including all schedules and exhibits hereto) and each of the Ancillary Agreements to which the Company is a party, and the consummation by the Company of
the transactions contemplated hereby and thereby, have been duly authorized by all necessary corporate action. This Agreement (including all schedules and exhibits hereto) and the Ancillary Agreements to which the Company is a party have been duly
executed and delivered by the Company and constitute valid and binding obligations of the Company, enforceable against the Company in accordance with their respective terms, except as such enforceability may be limited by (i) bankruptcy,
insolvency, receivership, moratorium or other similar laws affecting the enforcement of creditors’ rights generally and (ii) the availability of equitable remedies may be limited by equitable principles of general applicability. The
execution of, and performance of, the 

  
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transactions contemplated by this Agreement (including all schedules and exhibits) and the Ancillary Agreements and compliance with the respective provisions thereof by the Company will not, to
the Company’s knowledge, violate any provision of law and will not conflict with or result in any material breach of any of the terms, conditions or provisions of, or constitute a material default under, or require a consent or waiver under,
(x)(i) the Charter or the By-Laws or (ii) any material indenture, lease, agreement or other instrument to which the Company is a party or by which it or any of its properties (whether tangible or intangible) is bound, or (y) any decree,
judgment, order, statute, rule or regulation applicable to the Company. 
 3.3 Governmental Consents. Except for
such qualifications or filings under applicable securities laws as may be required in connection with the transactions contemplated by this Agreement or as provided in Schedule 3.3 hereto, no consent, approval, order or authorization of, or
registration, qualification, designation, declaration or filing with, any governmental authority is required on the part of the Company in connection with the execution and delivery of this Agreement (including all schedules and exhibits hereto) and
the Ancillary Agreements to which the Company is a party, the offer, issuance, sale and delivery of the Securities, or the other transactions to be consummated at the Closing, as contemplated by this Agreement (including all schedules and exhibits
hereto), except such filings as shall have been made prior to and shall be effective on and as of the Closing. Based in part on the representations made by the Purchasers in Section 4 hereof, the offer, sale and issuance of the
Securities to the Purchasers will be in compliance with all applicable federal and state securities laws. 
 3.4
Litigation. Except as provided in Schedule 3.4 hereto, there is no action, suit or proceeding, or governmental inquiry or investigation, pending against the Company or, to the Company’s knowledge, threatened against the
Company or threatened or pending against any of the Company’s directors or executive officers, including, without limitation, any litigation which questions the validity of this Agreement (including all schedules and exhibits hereto) or the
Ancillary Agreements or the right of the Company to enter into any of them, nor is there any litigation pending against the Company or, to the Company’s knowledge, threatened against the Company or threatened or pending against any of the
Company’s directors or executive officers by reason of activities of the Company or negotiations by the Company or any of the directors or executive officers with possible investors in the Company. There is not any action, suit, proceeding or
investigation pending or, to the Company’s knowledge, threatened against the Company involving the prior employment of any of the Company’s employees or their obligations under any agreements with prior employers. Except as provided in
Schedule 3.4 hereto, there is no action, suit, proceeding or investigation by the Company currently pending or that the Company intends to initiate. The Company is not a party or subject to the provisions of any order, writ, injunction,
judgment or decree of any court or government agency or instrumentality. 
 3.5 Capitalization. Upon filing the
Charter and prior to the issuance of the Shares hereunder at the Closing, the Company has a total authorized capitalization consisting of: (a) 142,255,835 shares of Common Stock, par value $0.001 par value per share (the “Common
Stock”), of which (i) 141,963,421 shares have been designated Series A Common Stock, of which (A) 8,194,399 shares are issued and outstanding; (B) 37,200,000 shares have been reserved for issuance upon conversion of the
Company’s Series B 

  
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Preferred Stock, $0.001 par value per share (“Series B Preferred Stock”); (C) 12,090,672 shares have been reserved for issuance upon conversion of the Company’s Series
C Preferred Stock, $0.001 par value per share (“Series C Preferred Stock”); (D) 33,634,669 shares have been reserved for issuance upon conversion of the Company’s Series D Preferred Stock, $0.001 par value per share (the
“Series D Preferred Stock”); (E) 33,248,426 shares have been reserved for issuance upon conversion of the Series E Preferred Stock; (F) 2,480,000 shares have been reserved for issuance upon exercise of outstanding warrants
to purchase shares of Series B Preferred Stock; (G) 666,666 shares have been reserved for issuance upon exercise of warrants to purchase shares of Series E Preferred Stock; and (H) 14,836,268 shares will be reserved for issuance under the
Company’s 2009 Equity Incentive Plan, as amended (the “Plan”), and (ii) 292,414 shares have been designated Series B Common Stock, $0.001 par value per share, of which (A) 34,569 will be issued and outstanding, and
(B) 257,845 will be reserved for issuance upon conversion of the Company’s Series A Common Stock; and (b) 117,884,018 shares of Preferred Stock, $0.001 par value per share (the “Preferred Stock”), of which
(i) 39,680,000 shares have been designated Series B Preferred Stock, 37,200,000 of which are issued and outstanding and 2,480,000 of which are reserved for issuance upon exercise of outstanding warrants; (ii) 12,090,672 shares have been
designated Series C Preferred Stock, all of which will be issued and outstanding; (iii) 32,511,979 shares have been designated Series D Preferred Stock, all of which will be issued and outstanding; and (iv) 33,601,367 shares have been
designated Series E Preferred Stock, 17,111,567 of which are issued and outstanding. All of the issued and outstanding shares of the Company’s capital stock have been duly authorized and validly issued and are fully paid and nonassessable, and
were issued in accordance with the registration or qualification provisions of the Securities Act of 1933, as amended (the “Securities Act”). Except as set forth in Schedule 3.5 or as otherwise provided in this Agreement,
(1) no subscription, warrant, option, convertible security or other right (contingent or otherwise) to purchase or acquire any shares of capital stock of the Company is authorized or outstanding, (2) the Company has no obligation
(contingent or otherwise) to issue any subscription, warrant, option, convertible security or other such right or to issue or distribute to holders of any shares of its capital stock any evidences of indebtedness or assets of the Company, and
(3) the Company has no obligation (contingent or otherwise) to purchase, redeem or otherwise acquire any shares of its capital stock or any interest therein or to pay any dividend or make any other distribution in respect thereof. The issuance
and sale of the Shares and all other outstanding shares of capital stock of the Company is in compliance with any and all applicable rights of first refusal, preemptive rights or similar rights of any third party. The rights, preferences, privileges
and restrictions of the Shares are as stated in the Charter. 
 3.6 Subsidiaries. The Company has no subsidiaries
and does not own or control, directly or indirectly, any shares or units of capital securities of any other corporation or any interest in any partnership, joint venture or other non-corporate business or charitable enterprise. 

3.7 Stockholder List and Agreements. Attached as Schedule 3.7 hereto is a true and complete list of the
stockholders, option holders and warrant holders of the Company immediately prior to the Closing, showing the number of shares of Common Stock, Preferred Stock, options to purchase shares of Common Stock and warrants exercisable for shares of Common
Stock or Preferred Stock held by each. Except as provided in Schedule 3.7 hereto, there are no agreements, written or oral, between the Company and any holder of its capital stock (including holders of derivative securities) or, to the
Company’s knowledge, among any holders of its 

  
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capital stock (including holders of derivative securities), relating to the acquisition (including, without limitation, rights of first refusal, preemptive rights or similar rights), disposition,
registration under the Securities Act, including the regulations promulgated thereunder, or voting of the capital stock (including derivative securities) of the Company. To the Company’s knowledge, none of such Persons has any direct or
indirect ownership interest in any firm or corporation with which the Company is affiliated or with which the Company has a direct business relationship, or any firm or corporation that competes with the Company, except that employees, officers, or
directors of the Company and members of their immediate families may own securities of publicly traded companies (not to exceed 2% of such companies’ capital stock) that may compete with the Company. 

3.8 Issuance of Securities. The issuance, sale and delivery of the Shares in accordance with this Agreement, and the
issuance and delivery of the shares of Series A Common Stock issuable upon conversion of the Shares, have been duly authorized by all necessary corporate action on the part of the Company, and all such shares have been duly reserved for issuance.
The Shares when so issued, sold and delivered against payment therefor in accordance with the provisions of this Agreement, and the Series E Conversion Shares, if and when issued upon such conversion, will be duly and validly issued, fully paid and
nonassessable and free of restrictions on transfer other than restrictions on transfer under the Ancillary Agreements, applicable federal and state securities laws and liens or encumbrances created by or imposed by a Purchaser. 

3.9 Financial Statements. Set forth on Schedule 3.9 is the last regularly prepared financial statements completed
prior to the Closing (the “Financial Statements”, and the date of the balance sheet included in the Financial Statements, the “Balance Sheet Date”). The Financial Statements are complete and correct, are in
accordance with the books and records of the Company and present fairly the financial condition, cash flow, changes in stockholder equity and results of operations of the Company as at the dates and for the periods indicated, subject in the case of
unaudited financial statements to normal year-end audit adjustments and the absence of footnotes. The Financial Statements have been prepared in accordance with Generally Accepted Accounting Principles applied on a consistent basis throughout the
periods indicated, except that the unaudited financial statements may not contain all footnotes required by Generally Accepted Accounting Principles. 
 3.10 Absence of Changes. Since the Balance Sheet Date and except as provided in Schedule 3.10 there has not been: (a) any change in the assets, liabilities, financial condition
or operations of the Company from that reflected in the Financial Statements, except changes in the ordinary course of business that have not had and cannot reasonably be expected to have a Material Adverse Effect; (b) any change, except
changes in the ordinary course of business that have not had and cannot reasonably be expected to have a Material Adverse Effect, in the contingent obligations of the Company by way of guaranty, endorsement, indemnity, warranty or otherwise;
(c) any damage, destruction or loss, whether or not covered by insurance, having or which could reasonably be expected to have a Material Adverse Effect; (d) any waiver or compromise by the Company of a valuable right or of a material debt
owed to it; (e) any loans made by the Company to the Company’s employees or directors other than travel advances made in the ordinary course of business; (f) any extraordinary increases in the compensation of any of the Company’s
employees or directors; (g) any declaration 

  
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or payment of any dividend or other distribution of the assets of the Company; (h) any issuance or sale by the Company (whether or not contingent) of any shares of its Common Stock,
Preferred Stock or any other securities (including derivative securities); (i) any transaction or agreement consummated or entered into by the Company other than in the ordinary course of business; (j) to the Company’s knowledge, any
other event or condition of any character that has or is reasonably likely to have a Material Adverse Effect; (k) any sale, assignment or transfer of any patents, trademarks, copyrights, trade secrets or other intangible assets (except for a
license granted in the ordinary course of business); or (l) the entrance by the Company into any agreement or commitment or the arising of any obligation by the Company to do any of the things described in this Section 3.10.

 3.11 Taxes. The Company has timely filed or has obtained presently effective extensions with respect to all
federal, state, county, local and foreign tax returns which are required to be filed by it (including, without limitation, those due in respect of its properties, income, franchises, licenses, sales and payrolls) and all taxes shown thereon to be
due have been timely paid with exceptions not material to the Company. The Company’s returns and reports are complete and accurate in all material respects. The Company has paid all taxes and other assessments due. Federal income tax returns of
the Company have not been audited by the Internal Revenue Service, and no controversy with respect to taxes of any type is pending or, to the Company’s knowledge, threatened. 

3.12 Property and Assets. 
 (a) The Company has good, clear, transferable and marketable title to all of its material properties and assets, whether tangible or intangible, and none of such properties or assets is subject to any
mortgage, pledge, lien, security interest, lease, license, charge or encumbrance, other than (i) those resulting from taxes which have not yet become delinquent, (ii) minor liens and encumbrances which do not materially detract from the
value of the property subject thereto or materially impair the operations of the Company, and (iii) those that have otherwise arisen in the ordinary course of business and do not materially detract from the value of the property subject thereto
or materially impair the operations of the Company. 
 (b) The Company has not granted rights to manufacture, produce, assemble,
license, market or sell its products to any Person and is not bound by any agreement that adversely affects the Company’s exclusive right to develop, manufacture, assemble, distribute, market or sell its products. 

(c) The Company hereby represents that it is not now and has never been a “United States real property holding corporation”, as
defined in Section 897(c)(2) of the Internal Revenue Code of 1986, as amended (the “Code”), and Treasury Regulation Section 1.897-2(b), and that the Company has filed with the Internal Revenue Service all statements, if
any, with its United States income tax returns, which are required under Treasury Regulation Section 1.897-2(h). 

  
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 3.13 Intellectual Property. 

(a) Schedule 3.13(a) lists all patents, patent applications, trademarks, service marks, trademark and service mark
registrations and registration applications, trade names, trade name registrations, logos, trade dress, and copyright registrations that are directly or indirectly owned or controlled in whole or in part by the Company or used in the business of the
Company as now being conducted (collectively, “Intellectual Property”), including, in the case of any Intellectual Property not owned by the Company, the licenses or other agreements or arrangements (other than for off-the-shelf
software programs that have not been customized for its use) pursuant to which the Company has the right to use such Intellectual Property. Except as set forth in Schedule 3.13(a) and excluding off-the-shelf software programs that have
not been customized for its use, (i) the Company owns, or is licensed or authorized or otherwise has the right to use all Intellectual Property as it is being used in the business of the Company as now being conducted without the payment of
royalties or other consideration (including any obligations to issue equity securities to any third party); and (ii) no governmental registration of any of the Intellectual Property has lapsed, expired or been cancelled, abandoned, opposed or
the subject of a reexamination request. 
 (b) In any instance where the Company’s rights to Intellectual Property arise
under a license or similar agreement (other than for off-the-shelf software programs that have not been customized for its use), this is indicated in Schedule 3.13. Except for Intellectual Property (i) indicated in Schedule
3.13(b) as owned by a third party and used by the Company under a license or similar agreement, or (ii) indicated in Schedule 3.13(b) as owned by the Company and licensed to a third party, the Company has not granted to any
other Person and, to the knowledge of the Company, no other Person has, an interest in or right or license to use any of the Intellectual Property. To the Company’s knowledge, none of the Intellectual Property is being infringed by others, or
is subject to any outstanding order, decree, judgment, or stipulation. No litigation (or other proceeding in or before any governmental agency or arbitral body) relating to or challenging the scope, validity or enforceability of any of the
Intellectual Property is pending, or to the Company’s knowledge, threatened, nor, to the Company’s knowledge, is there any basis for any such litigation or proceeding. The Company has kept secret and has not disclosed, except pursuant to
written confidentiality agreements, any trade secrets or confidential information included in the Company’s Intellectual Property and maintains reasonable security measures for the preservation of the secrecy and proprietary nature of its trade
secrets or other confidential information included in the Company’s Intellectual Property including the use of written confidentiality agreements with any Person receiving the same. 

(c) To the Company’s knowledge: (i) the Company has not infringed or made unlawful use of, and is not infringing or making
unlawful use of, any intellectual property or other proprietary or confidential information of any other Person; and (ii) the activities of the Company’s employees and contractors in connection with their employment or contractual
relationship with the Company do not violate any agreements or arrangements that any such employees or consultants have with any former employer or any other Person. No litigation (or other proceeding in or before any governmental agency or
arbitrator body) charging the Company with infringement or unauthorized or unlawful use of any patent, trademark, service mark, copyright or trade secret is pending, or to the Company’s knowledge, threatened. Except as indicated in Schedule
3.13(c), the Company has not received any cease-and-desist letter, offer to license or any other communication from any other Person identifying any intellectual property other than Intellectual Property as relevant to the Company’s
business as presently conducted or as proposed to be conducted. 
 (d) To the Company’s knowledge, no officer, director,
employee, or consultant of the Company is obligated under or bound by any agreement or instrument, or any judgment, decree, or order of any court or administrative agency, that conflicts or may conflict with his or her agreements and obligations to
promote the interests of the Company. 

  
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 3.14 Insurance. The Company maintains insurance covering its properties and
business adequate and customary for the type and scope of the Company’s properties and business. A list of all of the insurance coverage maintained by the Company is set forth in Schedule 3.14 hereto. The Company is not in default
with respect to payment of premiums on any such policy of insurance and no claim is pending under any such policy. 

3.15 Material Contracts and Obligations. Except as contemplated by this Agreement or as listed in Schedule
3.15 hereto, the Company is not a party to any material agreement or commitment of any nature, including without limitation: (a) any agreement that requires future expenditures by the Company in excess of $50,000 either individually or
in the aggregate, (b) any employment or consulting agreement, employee benefit, bonus, pension, profit-sharing, stock option, stock purchase or similar plan or arrangement, (c) any agreement with any stockholder, officer, director or, to
the Company’s knowledge, Affiliate (as such term is defined below) of the Company or any of their respective immediate family members, including without limitation any agreement or other arrangement providing for the furnishing of services by,
rental of real or personal property from, or otherwise requiring payments to, any such Person (to the Company’s knowledge, none of such Persons has any direct or indirect ownership interest in any firm or corporation with which the Company is
affiliated or with which the Company has a business relationship, or any firm or corporation that competes with the Company, except that employees, officers, or directors of the Company and members of their immediate families may own securities of
publicly traded companies (not to exceed two percent (2%) of such companies’ capital stock) that may compete with the Company), (d) any agreement relating to the transfer or license of any Intellectual Property, or (e) agreements
restricting the development, manufacture or distribution of the Company’s products or services, including any distributor or sales representative agreements. As to each agreement or commitment listed in Schedule 3.15: (i) the
Company is not in material default thereunder, and, to the Company’s knowledge, no other party thereto is in material default thereunder; (ii) no event has occurred which is or, after the giving of notice or passage of time or both, would
constitute a material breach thereof by the Company or, to the Company’s knowledge, by any other party thereto; (iii) the Company has not received written notice of an intention to cancel or terminate such agreement or commitment; and
(iv) the consummation of the transactions contemplated hereby will not constitute a material default thereunder or material breach thereof. The term “Affiliate” means any Person directly or indirectly controlling, controlled by
or under common control with another Person. 
 3.16 Absence of Undisclosed Liabilities. The Company has
not (i) declared or paid any dividends or authorized or made any distribution upon or with respect to any class or series of its capital stock, (ii) incurred any indebtedness for money borrowed or any other liabilities individually in
excess of $10,000 or, in the case of indebtedness and/or liabilities individually less than $10,000, in 

  
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excess of $100,000 in the aggregate (except for current liabilities incurred in the ordinary course of business), (iii) made any loans or advances to any Person, other than ordinary advances
for travel expenses, or (iv) sold, exchanged or otherwise disposed of any of its assets or rights, other than the sale of its inventory or license grants in the ordinary course of business. Except as listed in Schedule 3.16 hereto
or as fully disclosed or reserved for in the Financial Statements, the Company does not, to its knowledge, have any material obligations or liabilities (whether accrued, absolute, contingent, liquidated, unliquidated or otherwise, whether due or to
become due) (“Liabilities”) required by generally accepted accounting principles to be reflected on a balance sheet except (i) liabilities and obligations incurred after the date of the Financial Statements and (ii) future
performance obligations under the agreements and commitments to which or by which the Company is bound as of the date hereof. 

3.17 Compliance. The Company has, to its knowledge, complied with all laws, regulations and orders applicable to its
present business and has all material permits and licenses required thereby, except for any violation of or default under any laws, regulations or orders which will not have a Material Adverse Effect. There is no term or provision of any mortgage,
indenture, contract, agreement or instrument to which the Company is a party or by which it is bound or, to the Company’s knowledge, of any provision of any state or federal judgment, decree, order, statute, rule or regulation applicable to or
binding upon the Company that has a Material Adverse Effect or, as far as the Company may now foresee, in the future is reasonably likely to have a Material Adverse Effect. 

3.18 Employees. Set forth in Schedule 3.18 hereto is a list of the names of the executive officers and all
other employees of the Company, together with the title or job classification of each such individual. Except as set forth in Schedule 3.18 hereto, none of such Persons has an employment agreement or understanding, whether oral or
written, with the Company that is not terminable on less than 90 days’ notice by the Company without cost or other liability to the Company. All Persons identified in Schedule 3.18 have executed and delivered nondisclosure
and assignment of invention agreements in the form of Exhibit E attached hereto, and all of such agreements are in full force and effect. The Company is not aware that any of its employees are in violation thereof. None of the
Company’s employees is represented by any labor union, and there is no labor strike or other labor trouble pending or, to the Company’s knowledge, threatened with respect to the Company (including, without limitation, any organizational
drive). 
 3.19 ERISA. Except as set forth in Schedule 3.19 hereto, the Company does not
have or otherwise contribute to or participate in any employee benefit plan subject to the Employee Retirement Income Security Act of 1974, as amended. Schedule 3.19 hereto sets forth all of the employee benefit plans of the
Company. 
 3.20 Minute Books. The minute books of the Company accurately reflect all material information
relating to the meetings and other corporate actions of the Company’s stockholders and the Company’s Board of Directors (the “Board of Directors”) and any committees thereof. The stock ledger of the Company is complete and
reflects all issuances, transfers, repurchases and cancellations of shares of capital stock of the Company. 

  
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 3.21 Disclosures. The Company has provided each Purchaser with all the
information that such Purchaser has requested for deciding whether to purchase the Series E Preferred Stock. The Company has provided the Purchasers with all material information that the Company believes is reasonably necessary to enable such
Purchasers to decide whether to purchase the Series E Preferred Stock other than such information relating to matters which are not reasonably likely to have a Material Adverse Effect on the Company. Neither this Agreement (including all schedules
and exhibits hereto), nor the Ancillary Agreements (including all exhibits, annexes and schedules thereto), nor any report, certificate or instrument furnished to the Purchasers or its counsel in connection with the transactions contemplated by this
Agreement when read together, contains any untrue statement of a material fact or, to the Company’s knowledge, omits to state a material fact necessary in order to make the statements contained herein or therein, in light of the circumstances
under which they were made, not misleading. 
 3.22 Brokers. Except as set forth in Schedule
3.22, the Company has not retained any finder or broker in connection with the transactions contemplated by this Agreement and agrees to indemnify and save the Purchasers harmless from and against any and all claims, liabilities or
obligations with respect to brokerage or finders’ fees or commissions in connection with the transactions contemplated by this Agreement asserted by any Person on the basis of any agreement, statement or representation alleged to have been made
by the Company. 
 3.23 Third Party Consents. Except as set forth in Schedule 3.23, to the
Company’s knowledge, no consent or approval is needed from any third party in order to effect the issuance and sale of the Securities, or any of the other transactions contemplated by this Agreement (including schedules and exhibits hereto) and
the Ancillary Agreements. 
 4. REPRESENTATIONS AND WARRANTIES OF THE PURCHASERS. Each of the Purchasers represents and warrants
to the Company, on behalf of itself and not on behalf of the others, as follows: 
 4.1 Accredited
Investor. Such Purchaser is an “accredited investor” within the meaning of Rule 501(a) under the Securities Act, and understands that the Company has relied upon its being an accredited investor in deciding to proceed with the
transactions contemplated hereby, and in ascertaining the requirements of law applicable to the issuance and sale of the Shares being purchased hereby. The Purchaser’s financial condition is such that the Purchaser is able to bear all economic
risks of investment in the Securities, including a complete loss of the Purchaser’s investments therein. The Purchaser acknowledges that the Company has provided it with adequate access to financial and other information concerning the Company
as requested and that it has had the opportunity to ask questions of and receive answers from the Company concerning the transactions contemplated under this Agreement and the Ancillary Agreements and to obtain therefrom any additional information
necessary to make an informed decision regarding an investment in the Company. 
 4.2 Investment. The
Purchaser is acquiring the Securities, for its own account for investment and not with a view to, or for sale in connection with, any distribution thereof, nor with any present intention of distributing or selling the same; and, except as
contemplated by this Agreement and the Ancillary Agreements, the Purchaser has no present or contemplated agreement, undertaking, arrangement, obligation, indebtedness or commitment providing for the disposition thereof. 

  
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 4.3 Authority. The Purchaser has full power and authority to enter into and to
perform this Agreement and the Ancillary Agreements in accordance with their respective terms. The Purchaser represents that it has not been organized, reorganized or recapitalized specifically for the purpose of investing in the Company. This
Agreement and the Ancillary Agreements have been duly executed and delivered by the Purchaser and constitute valid and binding obligations of each enforceable against it in accordance with their respective terms. The execution of and performance of
the transactions contemplated by this Agreement and the Ancillary Agreements and compliance with the respective provisions thereof by each of the Purchasers will not, to its knowledge, violate any provision of law and, if applicable, will not
conflict with or result in any material breach of any of the terms, conditions or provisions of or constitute a material default under, or require a consent or waiver under, its organizational documents (if any, and each as amended to date and as in
effect as of the date hereof) or any indenture, lease, agreement or other instrument to which the Purchaser is a party or by which it or any of its properties (whether tangible or intangible) is bound, or any decree, judgment, order, statute, rule
or regulation applicable to the Purchaser. 
 4.4 Unregistered Securities. The Purchaser acknowledges and
agrees that the Securities, and any shares issuable upon conversion or exercise thereof, must be held indefinitely until such time as they are subsequently registered under the Securities Act or an exemption from such registration is available. The
Purchaser has been advised or is aware of the provisions of Rule 144 promulgated under the Securities Act, which currently permits limited resale of shares purchased in a private placement subject to the satisfaction of certain conditions,
including, among other things: the availability of certain current public information about the Company, the resale occurring not less than one year after a party has purchased and paid for the security to be sold, the sale being through an
unsolicited “broker’s transaction” or in transactions directly with a market maker (as such term is defined under the Securities Exchange Act of 1934, as amended (the “Exchange Act”)) and the number of shares being
sold during any three-month period not exceeding specified limitations. 
 4.5 Principal Place of Business.
The address of the residence or the principal place of business, as applicable, the latter of which is the office in which the Purchaser’s investment decision was made, is accurately set forth on Attachment 1. 

4.6 Brokers. The Purchaser has not retained any finder or broker in connection with the transactions contemplated by this
Agreement and the Purchaser separately agrees to indemnify and save the Company harmless from and against any and all claims, liabilities or obligations with respect to brokerage or finders’ fees or commissions in connection with the
transactions contemplated by this Agreement asserted by any Person on the basis of any agreement, statement or representation alleged to have been made by such Purchaser. 

4.7 Foreign Investors. If the Purchaser is not a United States Person (as defined by Section 7701(a)(30) of the Code),
such Purchaser hereby represents that it has satisfied itself as to the full observance of the laws of its jurisdiction in connection with any invitation to subscribe for the Securities or any use of this Agreement, including (i) the legal
requirements within its jurisdiction 

  
 -11-

 
for the purchase of the Securities, (ii) any foreign exchange restrictions applicable to such purchase, (iii) any government or other consents that may need to be obtained, and
(iv) the income tax and other tax consequences, if any, that may be relevant to the purchase, holding, redemption, sale or transfer of the Securities. The Company’s offer and sale and Purchaser’s subscription and payment for and
continued beneficial ownership of the Securities will not violate any applicable securities or other laws of Purchaser’s jurisdiction. 
 4.8 Transfer Restrictions. Each Purchaser acknowledges and agrees that the Shares and the Conversion Shares are subject to restrictions on transfer as set forth in the Investor Rights
Agreement. 
 5. CONDITIONS PRECEDENT OF THE PURCHASERS. Unless otherwise indicated below, the obligation of the Purchasers to
purchase Shares at the Closing is subject to the fulfillment, or the waiver by the Required Purchasers, of each of the following conditions (as applicable) on or before the Closing: 

5.1 Ancillary Agreements. 
 (a) Prior to the Closing, the Fourth Amended and Restated Investor Rights Agreement in the form attached hereto as Exhibit B (the “Investor Rights Agreement”) shall
have been executed and delivered by each Purchaser (other than any Purchaser relying upon this condition to excuse such Purchaser’s performance hereunder) such that upon the execution and delivery of the Investor Rights Agreement by the
Company, such Purchasers and a sufficient number of parties to that certain Third Amended and Restated Investors Rights Agreement dated June 13, 2013 by and between the Company and other parties thereto (the “Prior Investor Rights
Agreement”), the Prior Investor Rights Agreement shall be amended and restated in its entirety by the Investor Rights Agreement, and shall be in full force and effect as of the Closing. 

(b) Prior to the Closing, the Fourth Amended and Restated Voting Agreement in the form attached hereto as Exhibit C
(the “Voting Agreement”) shall have been executed and delivered by each Purchaser (other than any Purchaser relying upon this condition to excuse such Purchaser’s performance hereunder) such that upon the execution and delivery
of the Voting Agreement by the Company, such Purchasers and a sufficient number of parties to that certain Third Amended and Restated Voting Agreement dated June 13, 2013 by and between the Company and other parties thereto (the “Prior
Voting Agreement”), the Prior Voting Agreement shall be amended and restated in its entirety by the Investor Rights Agreement, and shall be in full force and effect as of the Closing. 

(c) Prior to the Closing, the Fourth Amended and Restated Right of First Refusal and Co-Sale Agreement in the form attached hereto as
Exhibit D (the “Co-Sale Agreement”) shall have been executed and delivered by each Purchaser (other than any Purchaser relying upon this condition to excuse such Purchaser’s performance hereunder) such that
upon the execution and delivery of the Co-Sale Agreement by the Company, such Purchasers and a sufficient number of parties to that certain Third Amended and Restated Co-Sale Agreement dated June 13, 2013 by and between the Company and other
parties thereto (the “Prior Co-Sale Agreement”), the Prior Co-Sale Agreement shall be amended and restated in its entirety by the Investor Rights Agreement, and shall be in full force and effect as of the Closing. 

(d) Prior to the Closing, the Company shall have executed and delivered the counterpart signature pages to the following agreements:
(i) the Investor Rights Agreement, (ii) the Voting Agreement, and (iii) the Co-Sale Agreement. 

  
 -12-

 5.2 Third Party Consents. The Company shall have obtained any and all material
consents, permits and waivers (including all authorizations, approvals or permits of any governmental authority or regulatory body of the United States of America or any state thereof) necessary or appropriate for consummation of the transactions
contemplated by this Agreement and the Ancillary Agreements, and the same shall be effective as of the date of the Closing, except for such as may be properly obtained subsequent to the date of the Closing. 

5.3 Certificates and Documents. The Company shall have delivered to the Purchasers: (a) certificates, as of the most
recent practicable date, as to the corporate good standing of the Company issued by the Secretary of State of the State of Delaware; and (b) a Certificate of the Secretary or an Assistant Secretary of the Company, dated as of the Closing Date,
certifying: (i) that attached thereto is a true and complete copy of the Charter; (ii) that attached thereto is a true and complete copy of the By-Laws; (iii) that attached thereto is a true and complete copy of the resolutions of the
Board of Directors and the stockholders of the Company authorizing and approving all matters in connection with this Agreement and the Ancillary Agreements and the transactions contemplated hereby and thereby; and (iv) to the incumbency and
specimen signature of certain officers of the Company. 
 5.4 Representations and Warranties. The
representations and warranties of the Company contained in Section 3 shall be true and correct in all material respects (except for those representations or warranties qualified by materiality, which shall be true and correct in all
respects) on and as of the Closing Date with the same effect as though such representations and warranties had been made on and as of the Closing Date; provided, however, that representations and warranties that speak as of a particular date shall
remain so true and correct as of such date. 
 5.5 Performance. The Company shall have performed and
complied with all agreements, obligations, covenants and conditions contained in this Agreement that are required to be performed or complied with by it at or before the Closing. 

5.6 Compliance Certificate. At the Closing, the Chief Executive Officer of the Company shall have delivered to the
Purchasers a certificate certifying that the conditions specified in Sections 5.4 and 5.5 have been fulfilled and stating that there has been no Material Adverse Effect since the Balance Sheet Date other than as disclosed in this
Agreement, including the schedules hereto. 
 5.7 Charter. The Charter shall have been filed with the
Secretary of State of Delaware and a certified copy of the Charter shall have been provided to the Purchasers. 
 5.8
Opinion of Counsel. The Purchasers shall have received an opinion from Lowenstein Sandler LLP, counsel for the Company, dated as of the Closing, addressed to the Purchasers, satisfactory in form and substance to Required Purchasers, in
the form of Exhibit F attached hereto.  

  
 -13-

 6. CONDITIONS PRECEDENT OF THE COMPANY. The obligation of the Company to issue Shares at the Closing
is subject to the fulfillment, or the waiver by the Company, of each of the following conditions on or before the applicable Closing: 
 6.1 Ancillary Agreements. Prior to the applicable Closing, the Purchasers shall have executed and delivered a counterpart signature page to the Ancillary Agreements, and each such Ancillary
Agreement shall be in full force and effect. 
 6.2 Representations and Warranties. The representations and
warranties of the Purchasers contained in Section 4 shall be true and correct on and as of the Closing Date with the same effect as though such representations and warranties had been made on and as of the Closing Date.

 6.3 Performance. The Purchasers shall have performed and complied with all agreements, obligations and
conditions contained in this Agreement that are required to be performed or complied with at or before the applicable Closing. 
 6.4 Third Party Consents. The Purchasers shall have obtained any and all material consents, permits and waivers (including all authorizations, approvals or permits of any governmental
authority or regulatory body of the United States of America or any state thereof) necessary or appropriate for consummation of the transactions contemplated by this Agreement and the Ancillary Agreements, and the same shall be effective as of the
date of the applicable Closing, except for such as may be properly obtained subsequent to the date of the applicable Closing. 
 6.5. Amendment of Initial Series E Purchase Agreement. The Company and the Previous Investors shall have entered into the Amendment.  

7. COVENANTS OF THE COMPANY 
 7.1 Nondisclosure Agreements. The Company shall require all persons now or hereafter employed by the Company or engaged by it as a consultant to enter into nondisclosure and assignment of
invention agreements if, and to the extent that, any have not previously been executed, substantially in the form of Exhibit E or such other form as may be approved from time to time by the Board of Directors. 

7.2 Reservation of Certain Shares of Capital Stock. The Company shall reserve and maintain a sufficient number of shares of
Series A Common Stock for issuance upon conversion of all of the outstanding Shares, duly taking into account the reduction of shares available for issuance due to conversion of all of the Company’s convertible securities and exercise of all of
the Company’s stock options as well as any increase in the number of shares of Series A Common Stock, issuable upon conversion of all convertible securities in accordance with the terms of the Charter or upon exercise of all such options in
accordance with the terms applicable thereto. 

  
 -14-

 7.3 Restrictive Agreements Prohibited. Neither the Company nor any of its
subsidiaries, if any, shall become a party to any agreement which, by its terms, restricts the Company’s ability to perform under or comply with the terms of this Agreement, the Ancillary Agreements to which the Company is a party or the
Charter. 
 7.4 Compliance with Laws. The Company shall comply, and cause each of its subsidiaries, if any,
to comply, with all applicable laws, rules, regulations and orders, the noncompliance with which is reasonably likely to have a Material Adverse Effect. 
 7.5 FIRPTA. The Company shall provide prompt notice to the Purchasers following any “determination date” (as defined in Treasury Regulation Section 1.897-2(c)(1)) on which the
Company becomes a United States real property holding corporation. In addition, upon a written request by a Purchaser, the Company shall provide such Purchaser with a written statement informing such Purchaser whether such Purchaser’s interest
in the Company constitutes a United States real property interest. The Company’s determination shall comply with the requirements of Treasury Regulation Section 1.897-2(h)(1) or any successor regulation, and the Company shall provide
timely notice to the Internal Revenue Service, in accordance with and to the extent required by Treasury Regulation Section 1.897-2(h)(2) or any successor regulation, that such statement has been made. The Company’s written statement to
such Purchaser shall be delivered to such Purchaser within ten (10) days of such Purchaser’s written request therefor. The Company’s obligation to furnish such written statement shall continue notwithstanding the fact that a class of
the Company’s stock may be regularly traded on an established securities market or the fact that there is no preferred stock then outstanding. 
 7.6 Insurance. The Company shall maintain (i) directors and officers liability insurance in an amount no less than $1.0 million and (ii) product liability insurance in an amount no
less than $1.0 million. 
 7.7 No Promotion. The Company agrees that it will not, and shall cause each of
its Subsidiaries to not, without the prior written consent of Fidelity Management & Research Company (“Fidelity”), use in advertising, publicity, or otherwise the name of Fidelity, or any Purchaser, or any partner or
employee of Fidelity or any Purchaser, nor any trade name, trademark, trade device, service mark, symbol or any abbreviation, contraction or simulation thereof owned by Fidelity, any Purchaser or any of their respective affiliates. The Company
further agrees that it shall obtain the written consent of Fidelity prior to the Company’s issuance of any public statement detailing the purchase of Securities by Purchasers pursuant to this Agreement.  

8. MISCELLANEOUS. 

8.1 Successors and Assigns. This Agreement, and the rights and obligations of each Purchaser hereunder, may be assigned by
the Purchaser to any Person to which Securities are transferred by the Purchaser, and such transferee shall be deemed to be the “Purchaser” for purposes of this Agreement; provided that the transferee provides written notice of such
assignment to the Company and agrees in writing to be bound by and comply with all provisions of this Agreement. 

  
 -15-

 8.2 Survival of Representations and Warranties. All covenants, representations
and warranties contained herein shall survive the execution and delivery of this Agreement and the closing of the transactions contemplated hereby and shall in no way be affected by any investigation of the subject matter thereof made by or on
behalf of the Purchasers or the Company. 
 8.3 Indemnification.  

(a) The Company agrees to indemnify and hold harmless each Purchaser and its respective directors, officers, trustees, members, managers,
employees and agents from and against any and all losses, claims, damages, liabilities and expenses (including without limitation reasonable attorney fees and disbursements and other expenses incurred in connection with investigating, preparing or
defending any action, claim or proceeding, pending or threatened and the costs of enforcement thereof) (collectively, “Losses”) to which such Person (as defined below) may become subject as a result of any breach of representation,
warranty, covenant or agreement made by or to be performed on the part of the Company under this Agreement and the Ancillary Agreements, and will reimburse any such Person for all such amounts as they are incurred by such Person. 

(b) Any Person entitled to indemnification hereunder shall (i) give prompt notice to the indemnifying party of any claim with
respect to which it seeks indemnification and (ii) permit such indemnifying party to assume the defense of such claim with counsel reasonably satisfactory to the indemnified party; provided that any Person entitled to indemnification
hereunder shall have the right to employ separate counsel and to participate in the defense of such claim, but the fees and expenses of such counsel shall be at the expense of such Person unless (a) the indemnifying party has agreed to pay such
fees or expenses, or (b) the indemnifying party shall have failed to assume the defense of such claim and employ counsel reasonably satisfactory to such Person or (c) in the reasonable judgment of any such Person, based upon written advice
of its counsel, a conflict of interest exists between such Person and the indemnifying party with respect to such claims (in which case, if the Person notifies the indemnifying party in writing that such Person elects to employ separate counsel at
the expense of the indemnifying party, the indemnifying party shall not have the right to assume the defense of such claim on behalf of such Person); and provided, further, that the failure of any indemnified party to give notice as
provided herein shall not relieve the indemnifying party of its obligations hereunder, except to the extent that such failure to give notice shall materially adversely affect the indemnifying party in the defense of any such claim or litigation. It
is understood that the indemnifying party shall not, in connection with any proceeding in the same jurisdiction, be liable for fees or expenses of more than one separate firm of attorneys at any time for all such indemnified parties. No indemnifying
party will, except with the consent of the indemnified party, consent to entry of any judgment or enter into any settlement that does not include as an unconditional term thereof the giving by the claimant or plaintiff to such indemnified party of a
release from all liability in respect of such claim or litigation. 
 8.4 Expenses. The parties acknowledge and
agree that the Company authorized Fidelity Mt. Vernon Street Trust: Fidelity Growth Company Fund, Fidelity Advisor Series VII: Fidelity Advisor Health Care Fund and Fidelity Select Portfolios: Medical Equipment and Systems Portfolio, collectively,
to engage one external legal counsel to lead the review of this Agreement, 

  
 -16-

 
the Ancillary Agreements and the Charter. On the Closing Date, the Company shall reimburse Fidelity for the reasonable legal fees and expenses of such counsel in connection with such review.
Except as set forth above, the Company and each of the Purchasers shall be responsible for their own fees and expenses in connection with the transactions contemplated hereby. 
 8.5 Notices. All notices required or permitted hereunder shall be in writing and shall be deemed effectively given: (i) upon personal delivery to the party to be notified,
(ii) when sent by confirmed electronic mail, telex or facsimile if sent during normal business hours of the recipient, if not, then on the next business day, (iii) five days after having been sent by registered or certified mail, return
receipt requested, postage prepaid, or (iv) one day after deposit with a nationally recognized overnight courier, specifying next day delivery, with written verification of receipt.  

If such notice is addressed to the Company, at 20 Independence Boulevard, 4th Floor, Warren, New Jersey 07059, Attention: Chief Executive
Officer, or at such other address or addresses as may have been furnished by ten days advance written notice in writing by the Company to such Purchaser. 
 If such notice is addressed to any Purchaser, at the address set forth in Attachment 1, or at such other address or addresses as may have been furnished by ten (10) days advance written
notice to the Company in writing by such Purchaser. 
 8.6 Entire Agreement. This Agreement and the Ancillary
Agreements (including all exhibits, schedules and annexes to each) and the Charter embody the entire agreement and understanding between the parties hereto with respect to the subject matter hereof and supersede all prior agreements and
understandings relating to such subject matter. 
 8.7 Amendments. Except as otherwise expressly set forth
in this Agreement, any term of this Agreement may be amended and the observance of any term of this Agreement may be waived (either generally or in a particular instance and either retroactively or prospectively), only with the written consent of
the Company and the Required Purchasers. Any amendment or waiver effected in accordance with this Section 8.7 shall be binding upon the Company, each Purchaser and each future holder of any Securities. 

8.8 Counterparts. This Agreement, and any amendment hereto, may be executed in one or more counterparts, each of which
shall be deemed to be an original, but all of which shall be one and the same document. 
 8.9 Section Headings;
Schedules. The section headings are for the convenience of the parties only and in no way alter, modify, amend, limit or restrict the contractual obligations of the parties. Any matter disclosed as to any section of this Agreement in the
schedules hereto shall be deemed to be disclosed as to all sections of the Agreement. 
 8.10 Severability.
The invalidity or unenforceability of any provision of this Agreement shall not affect the validity or enforceability of any other provision of this Agreement. 

  
 -17-

 8.11 Governing Law. This Agreement shall be governed by and construed in
accordance with the internal, substantive laws of the State of Delaware excluding any choice of laws rule or principle that would result in the application of the substantive laws of any other jurisdiction. The parties hereto agree that any action
brought under or in relation to this Agreement, including without limitation to interpret or enforce any provision of this Agreement, shall be brought in, and each party agrees to and does hereby submit to the jurisdiction and venue of, any state or
federal court located in the State of New Jersey. 
 8.12 No Implied Rights or Remedies. Except as
otherwise expressly provided herein, nothing herein expressed or implied is intended or shall be construed to confer upon or to give any Person, except the Purchasers and the Company, and their respective successors and assigns permitted under this
Agreement, any rights or remedies under or by reason of this Agreement. 
 8.13 Construction. The language
used in this Agreement will be deemed to be the language chosen by the parties to express their joint and mutual intent, and no rule of strict construction will be applied against any party. 

8.14 Singular, Plural, Etc. Words in the singular include the plural, and words in the plural include the singular, in each
case as the context may require. Where a provision is qualified with respect to knowledge of the Company, such knowledge shall be imputed if any individual Company officer actually possesses such knowledge. “Days” and any other
measure of time shall be construed to include weekends and holidays unless otherwise specified. “Person” means any individual, corporation, limited liability company, partnership, joint venture, association, joint-stock company,
trust, unincorporated organization or government (including any agency or political subdivision thereof). In addition, the word “or” shall not be construed as requiring exclusivity. Whenever the context requires, the neuter gender shall
include the masculine and feminine genders. 
 8.15 Delays or Omissions. No delay or omission to exercise
any right, power or remedy accruing to any holder of any of the Securities, upon any breach or default of the Company under this Agreement, shall impair any such right, power or remedy of such holder nor shall it be construed to be a waiver of any
such breach or default, or an acquiescence therein, or of or in any similar breach or default thereafter occurring; nor shall any waiver of any single breach or default be deemed a waiver of any other breach or default theretofore or thereafter
occurring. Any waiver, permit, consent or approval of any kind or character on the part of any holder of any breach or default under this Agreement, or any waiver on the part of any holder of any provisions or conditions of this Agreement, must be
in writing and shall be effective only to the extent specifically set forth in such writing. All remedies, either under this Agreement or by law or otherwise afforded to any holder, shall be cumulative and not alternative. 

8.16 California Corporate Securities Law. THE SALE OF THE SECURITIES WHICH ARE THE SUBJECT OF THIS AGREEMENT HAS NOT BEEN
QUALIFIED WITH THE COMMISSIONER OF CORPORATIONS OF THE STATE OF CALIFORNIA AND THE ISSUANCE OF SUCH SECURITIES OR THE PAYMENT OR RECEIPT OF ANY PART OF THE CONSIDERATION THEREFOR PRIOR TO SUCH QUALIFICATION OR IN THE ABSENCE OF AN EXEMPTION FROM
SUCH QUALIFICATION IS UNLAWFUL. PRIOR TO ACCEPTANCE OF SUCH CONSIDERATION BY THE COMPANY, 

  
 -18-

 
THE RIGHTS OF ALL PARTIES TO THIS AGREEMENT ARE EXPRESSLY CONDITIONED UPON SUCH QUALIFICATION BEING OBTAINED OR AN EXEMPTION FROM SUCH QUALIFICATION BEING AVAILABLE. 

8.17 Specific Performance. The parties hereto agree that: (a) in the event of any breach or threatened breach by any
party of any covenant, obligation, or other provision of this Agreement applicable to such party, the other party shall be entitled (in addition to any other remedy that may be available) to (i) a decree or order of specific performance or
mandamus to enforce the observance and performance of such covenant, obligation or other provision, and (ii) an injunction restraining such breach or threatened breach; and (b) neither such other party shall be required to provide any bond
or other security in connection with any such decree, order or injunction or in connection with any related action or proceeding. 
 8.18 Defined Terms. As used herein, the following terms not otherwise defined have the following meanings: 
 “Material Adverse Effect” means a material adverse effect on the business, assets, operations or condition, financial or otherwise, of the Company; provided however, in no event shall any
of the following, either individually or in combination, constitute a Material Adverse Effect: (a) changes in general business or economic conditions in the Company’s industry, (b) any circumstance, change, or effect solely resulting
from or arising out of, directly or indirectly, the fact that Company or any Purchaser (rather than another party) is a party to the transactions contemplated by this Agreement; or (c) any failure by Company to meet internal projections of
forecasts or predictions for any period. 
 8.19 Other Defined Terms. Each of the following terms shall have the
meanings ascribed to such terms in the section set forth opposite such term:  
  

									
	 Defined Term
	  	 Section
	  	  	  	 Defined Term
	  	 Section

					
	 Affiliate
	  	3.15	  		  	Liabilities	  	3.16
					
	 Agreement
	  	Preamble	  		  	Losses	  	8.3(a)
					
	 Ancillary Agreements
	  	3.1	  		  	Material Adverse Effect	  	8.18
					
	 Balance Sheet Date
	  	3.9	  		  	Person	  	8.14
					
	 Board of Directors
	  	3.20	  		  	Plan	  	3.5
					
	 By-Laws
	  	3.1	  		  	Preferred Stock	  	3.5
					
	 Charter
	  	1.1	  		  	Prior Co-Sale Agreement	  	5.1
					
	 Closing
	  	2.2	  		  	Prior Investor Rights Agreement	  	5.1
					
	 Closing Date
	  	2.2	  		  	Prior Voting Agreement	  	5.1
					
	 Common Stock
	  	3.5	  		  	Purchaser(s)	  	Preamble
					
	 Company
	  	Preamble	  		  	Securities Act	  	3.5
					
	 Conversion Shares
	  	1.1	  		  	Series A Common Stock	  	3.5
					
	 Co-Sale Agreement
	  	5.1	  		  	Series B Preferred Stock	  	3.5
					
	 Days
	  	8.14	  		  	Series C Preferred Stock	  	3.5
					
	 Disclosure Schedules
	  	3	  		  	Series D Preferred Stock	  	3.5
					
	 Exchange Act
	  	4.4	  		  	Series E Preferred Stock	  	Recitals
					
	 Financial Statements
	  	3.9	  		  	Shares	  	1.1
					
	 Intellectual Property
	  	3.13	  		  	Voting Agreement	  	5.1
					
	 Investor Rights Agreement
	  	5.1	  		  		  	

 [Remainder of page intentionally left blank.] 

  
 -19-

 IN WITNESS WHEREOF, and intending to be legally bound hereby, the parties hereto have
caused this Series E Preferred Stock Purchase Agreement to be duly executed and delivered as an agreement under seal as of the date and year first above written. 

 

			
	COMPANY
	
	ROKA BIOSCIENCE, INC.
		
	By:	 	 /s/ Paul Thomas

	Name:	 	Paul Thomas
	Title:	 	President and CEO

 IN WITNESS WHEREOF, and intending to be legally bound hereby, the parties hereto have
caused this Series E Preferred Stock Purchase Agreement to be duly executed and delivered as an agreement under seal as of the date and year first above written. 

 

			
	PURCHASERS
	
	LEERINK SWANN HOLDINGS, LLC
		
	By:	 	 /s/ Jeffrey A. Leerink

	Name:	 	Jeffrey A. Leerink
	Title:	 	Chief Executive Officer
	
	LEERINK SWANN CO-INVESTMENT FUND, LLC
		
	By:	 	 /s/ Jeffrey A. Leerink

	Name:	 	Jeffrey A. Leerink
	Title:	 	Manager

 IN WITNESS WHEREOF, and intending to be legally bound hereby, the parties hereto have
caused this Series E Preferred Stock Purchase Agreement to be duly executed and delivered as an agreement under seal as of the date and year first above written. 

 

			
	PURCHASERS
	
	FIDELITY MT. VERNON STREET TRUST:
	FIDELITY GROWTH COMPANY FUND
		
	By:	 	 /s/ Adrien Deberghes

	Name:	 	Adrien Deberghes
	Title:	 	Deputy Treasurer
	
	FIDELITY ADVISOR SERIES VII:
	FIDELITY ADVISOR HEALTH CARE FUND
		
	By:	 	 /s/ Adrien Deberghes

	Name:	 	Adrien Deberghes
	Title:	 	Deputy Treasurer
	
	FIDELITY SELECT PORTFOLIOS:
	MEDICAL EQUIPMENT AND SYSTEMS PORTFOLIO
		
	By:	 	 /s/ Adrien Deberghes

	Name:	 	Adrien Deberghes
	Title:	 	Deputy Treasurer

 ATTACHMENT 1 

 

									
	 Name of Purchaser and Address
	  	Shares Purchased	 	  	Purchase Price	 
			
	 Fidelity Mt. Vernon Street Trust: Fidelity Growth Company Fund

Ball & Co

C/o Citibank N.A/Custody

IC&D Lock Box

P.O Box 7247-7057

Philadelphia, P.A 19170-7057

Account #: 206681
	  	 	7,841,600	  	  	$	9,998,040.00	  
			
	 Fidelity Advisor Series VII: Fidelity Advisor Health Care Fund

M.Gardiner & Co

C/O JPMorgan Chase Bank, N.A

P.O. Box 35308

Newark, NJ 07101-8006
	  	 	1,372,273	  	  	$	1,749,648.08	  
			
	 Fidelity Select Portfolios: Medical Equipment and Systems Portfolio

Brown Brothers Harriman & Co.

525 Washington Blvd

Jersey City NJ 07310

Attn: Michael Lerman 15th Floor

Corporate Actions
	  	 	3,136,640	  	  	$	3,999,216.00	  
			
	 Leerink Swann Holdings, LLC

1 Federal Street

Boston, MA 02110

Attn: Jeffrey A. Leerink, CEO

Attn: Timothy A. G. Gerhold, General Counsel
	  	 	490,099	  	  	$	624,876.23	  
			
	 Leerink Swann Co-Investment Fund, LLC

1 Federal Street

Boston, MA 02110

Attn: Jeffrey A. Leerink, CEO

Attn: Timothy A. G. Gerhold, General Counsel
	  	 	490,099	  	  	$	624,876.23EX-10.15

 Exhibit 10.15 
 This LOAN AND SECURITY AGREEMENT (this “Agreement”) is entered into as of November 21, 2013, by and between Comerica Bank (“Bank”) and ROKA BIOSCIENCE, INC.
(“Borrower”). 
 RECITALS 
 Borrower wishes to obtain credit from time to time from Bank, and Bank desires to extend credit to Borrower. This Agreement sets forth the terms on which Bank will advance credit to Borrower, and Borrower
will repay the amounts owing to Bank. 
 AGREEMENT 
 The parties agree as follows: 
  

	 	1.	DEFINITIONS AND CONSTRUCTION. 

 1.1 Definitions. As used in this Agreement, all capitalized terms shall have the definitions set forth on Exhibit A. Any term used in the Code and not defined herein shall have the meaning
given to the term in the Code. 
 1.2 Accounting Terms. Any accounting term not specifically defined on Exhibit A
shall be construed in accordance with GAAP and all calculations shall be made in accordance with GAAP. The term “financial statements” shall include the accompanying notes and schedules. 

 

	 	2.	LOAN AND TERMS OF PAYMENT. 

2.1 Credit Extensions. 
 (a) Promise to Pay. Borrower promises to pay to Bank, in lawful money of the United States of America, the aggregate unpaid principal amount of all Credit Extensions made by Bank to Borrower,
together with interest on the unpaid principal amount of such Credit Extensions at rates in accordance with the terms hereof. 

(b) Growth Capital Advances. 
 (i) Subject to and upon the terms and conditions of this Agreement, Bank agrees to make a Growth Capital Advance to Borrower. Borrower shall request, on the Closing Date, a Growth Capital Advance in an
amount equal to the Growth Capital Line. 
 (ii) Interest shall accrue from the date of the Growth Capital Advance at the rate
specified in the Pricing Addendum, and shall be payable in accordance with Section 2.3(b) and on the terms set forth in the Pricing Addendum. Any portion of the Growth Capital Advance that is outstanding on the last day of the Interest Only
Period shall be payable in equal monthly installments of principal, plus all accrued interest (based on a thirty three (33) month amortization schedule if the Interest Only Period is fifteen (15) months long and based on a thirty
(30) month amortization schedule if the Interest Only Period is eighteen (18) months long), beginning in each case on the first day of the month immediately following the last day of the Interest Only Period, and continuing on the same day
of each month thereafter through the Growth Capital Maturity Date, at which time Borrower shall pay all remaining principal due under the Growth Capital Advance in one final payment (the “Balloon Payment”), together with any other amounts
due under this Agreement. Once repaid, the Growth Capital Advance may not be reborrowed. 
 (iii) Prepayment. So long as
no Event of Default has occurred and is continuing, Borrower shall have the option to prepay all, or any part, of the Growth Capital Advance advanced by Bank under this Agreement in the inverse order of maturity, provided Borrower (i) delivers
written notice to Bank of its election to prepay the Growth Capital Advance at least fifteen (15) days prior to such prepayment, and (ii) pays, on the date of such prepayment: (A) a prepayment premium equal to two percent
(2.0%) of the amount prepaid if the prepayment is made on or before the first anniversary of the Closing Date (the “Prepayment Premium”); 

  
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and (B) all accrued and unpaid interest with respect to the Growth Capital Advance through the date the prepayment is made and all unpaid principal with respect to the Growth Capital
Advance; and (C) the Final Payment (or, if the Prepayment Premium is partial, a pro rata portion of the Final Payment) and all other sums, if any, that shall have become due and payable under this Agreement, including interest at the default
rate with respect to any past due amounts. Borrower shall pay the Prepayment Premium upon the acceleration of the Obligations by Bank or if this Agreement is terminated by Bank upon the occurrence of an Event of Default. 

(iv) Borrower shall notify Bank of its request for the Growth Capital Advance (which notice shall be irrevocable) by facsimile
transmission on the Closing Date. Such notice shall be substantially in the form of Exhibit C. The notice shall be signed by a Responsible Officer or its designee. Bank shall be entitled to rely on any facsimile or telephonic notice
given by a person who Bank reasonably believes to be a Responsible Officer or a designee thereof, and Borrower shall indemnify and hold Bank harmless for any damages or loss suffered by Bank as a result of such reliance. 

2.2 [Intentionally Omitted]. 
 2.3 Interest Rates, Payments, and Calculations. 
 (a) Interest
Rates. 
 (i) Growth Capital Advance. The Growth Capital Advance shall bear interest, on the outstanding daily
balance thereof, on the terms set forth in the Pricing Addendum. 
 (b) Payments. Bank shall, at its option, charge such
interest, all Bank Expenses, and all Periodic Payments against any of Borrower’s deposit accounts or against the Growth Capital Line, in which case those amounts shall thereafter accrue interest at the rate then applicable hereunder. Any
interest not paid when due shall be compounded by becoming a part of the Obligations, and such interest shall thereafter accrue interest at the rate then applicable hereunder. Payments and other amounts owing by Borrower to Bank will be made via
auto debit from Borrower’s account at the Bank. 
 2.4 Crediting Payments. Prior to the occurrence of an Event of
Default, Bank shall credit a wire transfer of funds, check or other item of payment to such deposit account or Obligation as Borrower specifies After the occurrence and during the continuance of an Event of Default, Bank shall have the right, in its
sole discretion, to immediately apply any wire transfer of funds, check, or other item of payment Bank may receive to conditionally reduce Obligations, but such applications of funds shall not be considered a payment on account unless such payment
is of immediately available federal funds or unless and until such check or other item of payment is honored when presented for payment. Notwithstanding anything to the contrary contained herein, any wire transfer or payment received by Bank after
12:00 noon Pacific time shall be deemed to have been received by Bank as of the opening of business on the immediately following Business Day. Whenever any payment to Bank under the Loan Documents would otherwise be due (except by reason of
acceleration) on a date that is not a Business Day, such payment shall instead be due on the next Business Day, and additional fees or interest, as the case may be, shall accrue and be payable for the period of such extension. 

2.5 Fees. Borrower shall pay to Bank the following: 
 (a) Commitment Fee. On the Closing Date, a fee equal to Seven Thousand Five Hundred Dollars ($7,500), which shall be fully earned and nonrefundable as of the Closing Date; 

(b) Final Payment. On the earlier of (i) the Growth Capital Maturity Date or (ii) the prepayment, acceleration or
termination of the Growth Capital Line or this Agreement, in addition to the outstanding principal, accrued and unpaid interest, and all other amounts due on such date with respect to the Growth Capital Line (including the Prepayment Premium in
accordance with the terms of this Agreement, pro-rated for any partial prepayment), an amount equal to Twenty Thousand Dollars ($20,000) (the “Final Payment”); and 
 (c) Bank Expenses. On the Closing Date, all Bank Expenses incurred through the Closing Date, and, after the Closing Date, all Bank Expenses, as and when they become due. 

  
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 2.6 Term. This Agreement shall become effective on the Closing Date and, subject to
Section 13.8, shall continue in full force and effect for so long as any Obligations remain outstanding or Bank has any obligation to make Credit Extensions under this Agreement. Notwithstanding the foregoing, Bank shall have the right to
terminate its obligation to make Credit Extensions under this Agreement immediately and without notice upon the occurrence and during the continuance of an Event of Default. 

 

	 	3.	CONDITIONS OF LOANS. 

 3.1
Conditions Precedent to Initial Credit Extension. The obligation of Bank to make the initial Credit Extension is subject to the condition precedent that Bank shall have received, in form and substance satisfactory to Bank, the following
(except as otherwise provided): 
 (a) this Agreement; 

(b) an officer’s certificate of Borrower with respect to incumbency and resolutions authorizing the execution and delivery of this
Agreement and the Loan Documents; 
 (c) the Pricing Addendum; 

(d) a financing statement (Form UCC-1); 
 (e) agreement to furnish insurance; 
 (f) payment of the fees and Bank Expenses
then due specified in Section 2.5; 
 (g) current SOS Reports indicating that except for Permitted Liens, there are no
other security interests or Liens of record in the Collateral; 
 (h) current financial statements, including audited
statements for Borrower’s most recently ended fiscal year, company prepared consolidated and consolidating balance sheets and income statements for the most recently ended month in accordance with Section 6.2, and such other updated
financial information as Bank may reasonably request; 
 (i) current Compliance Certificate in accordance with
Section 6.2; 
 (j) a Warrant in form and substance satisfactory to Bank; 

(k) a Collateral Information Certificate; 
 (l) an Automatic Loan Payment Authorization; 
 (m) an agreement, duly executed by
each third party in possession of Borrower’s assets, including but not limited to: 
  

	 	(i)	a Notice of Security Interest regarding Borrower’s inventory held with FedEx (Tennessee); 

 

	 	(ii)	an inventory holder’s acknowledgment regarding Borrower’s inventory held with Technical Transportation Inc. (Tennessee); 

(n) a landlord waiver duly executed by the landlord of each location at which Borrower leases real property, including but not limited
to 

  
 -3-

	 	(i)	a landlord waiver duly executed by the landlord (10398 Pacific Center Court, San Diego, CA), provided that such fully executed agreement may be delivered to Bank within
30 days after the Closing Date; 

  

	 	(ii)	a landlord waiver duly executed by the landlord (20 Independence Blvd., 4th Floor, Warren, NJ); 

(o) evidence satisfactory to Bank that Borrower received, prior to June 30, 2013, net cash proceeds in an amount equal to at least
Twenty Five Million Dollars ($25,000,000); 
 (p) a Subordination Agreement, duly executed by TriplePoint Capital LLC
(“TriplePoint”); and 
 (q) such other documents or certificates, and completion of such other matters, as Bank may
reasonably deem necessary or appropriate. 
 3.2 Conditions Precedent to all Credit Extensions. The obligation of Bank to
make each Credit Extension, including the initial Credit Extension, is further subject to the following conditions: 
 (a)
timely receipt by Bank of the Payment/Advance Form as provided in Section 2.1; and 
 (b) the representations and
warranties contained in Article 5 shall be true and correct in all material respects on and as of the date of such Payment/Advance Form and on the effective date of each Credit Extension as though made at and as of each such date, and no Event of
Default shall have occurred and be continuing, or would exist after giving effect to such Credit Extension (provided, however, that those representations and warranties expressly referring to another date shall be true, correct and complete in all
material respects as of such date). The making of each Credit Extension shall be deemed to be a representation and warranty by Borrower on the date of such Credit Extension as to the accuracy of the facts referred to in this Section 3.2.

  

	 	4.	CREATION OF SECURITY INTEREST. 

 4.1 Grant of Security Interest. Borrower grants and pledges to Bank a continuing security interest in the Collateral to secure prompt repayment of any and all Obligations and to secure prompt
performance by Borrower of each of its covenants and duties under the Loan Documents. Except as set forth in the Schedule, such security interest constitutes a valid, first priority security interest in the presently existing Collateral, and will
constitute a valid, first priority security interest in later-acquired Collateral. Except as expressly permitted by Section 7.1, Borrower also hereby agrees not to sell, transfer, assign, mortgage, pledge, lease, grant a security interest in,
or encumber any of its Intellectual Property; provided that other than non-exclusive licenses given in the ordinary course of Borrower’s business and Permitted Transfers, in the event Borrower transfers, sells, assigns, grants a security
interest in, hypothecates, permits or suffer to exist any Lien, or otherwise transfers any interest in or encumbers any material portion of the Intellectual Property (including through the grant of a negative pledge on the Intellectual Property to
any Person other than Bank), either voluntarily or involuntarily, without Bank’s prior written consent, Bank’s security interest shall include (and shall be deemed to have a Lien in such assets included from November 21, 2013) all
Intellectual Property. Notwithstanding any termination of this Agreement, Bank’s Lien on the Collateral shall remain in effect for so long as any Obligations are outstanding. 

4.2 Perfection of Security Interest. Borrower authorizes Bank to file at any time financing statements, continuation statements,
and amendments thereto that (i) either specifically describe the Collateral or describe the Collateral as all assets of Borrower of the kind pledged hereunder, and (ii) contain any other information required by the Code for the sufficiency
of filing office acceptance of any financing statement, continuation statement, or amendment, including whether Borrower is an organization, the type of organization and any organizational identification number issued to Borrower, if applicable. Any
such financing statements may be filed by Bank at any time in any jurisdiction whether or not Division 9 of the Code is then in effect in that jurisdiction. Borrower shall from time to time endorse and deliver to Bank, at the request of Bank, all
Negotiable Collateral and other documents that Bank 

  
 -4-

 
may reasonably request, in form satisfactory to Bank, to perfect and continue perfection of Bank’s security interests in the Collateral and in order to fully consummate all of the
transactions contemplated under the Loan Documents. Borrower shall have possession of the Collateral, except where expressly otherwise provided in this Agreement or where Bank chooses to perfect its security interest by possession in addition to the
filing of a financing statement. Where Collateral is in possession of a third party bailee, Borrower shall take such steps as Bank reasonably requests for Bank to (i) obtain an acknowledgment, in form and substance satisfactory to Bank, of the
bailee that the bailee holds such Collateral for the benefit of Bank, (ii) obtain “control” of any Collateral consisting of investment property, deposit accounts, securities accounts, letter-of-credit rights or electronic chattel
paper (as such items and the term “control” are defined in Division 9 of the Code) by causing the securities intermediary or depositary institution or issuing bank to execute a control agreement in form and substance satisfactory to Bank.
Borrower will not create any chattel paper without placing a legend on the chattel paper acceptable to Bank indicating that Bank has a security interest in the chattel paper. Borrower from time to time may deposit with Bank specific cash collateral
to secure specific Obligations; Borrower authorizes Bank to hold such specific balances in pledge and to decline to honor any drafts thereon or any request by Borrower or any other Person to pay or otherwise transfer any part of such balances for so
long as the specific Obligations are outstanding. 
 4.3 Right to Inspect. Bank (through any of its officers, employees,
or agents) shall have the right, upon ten (10) business days’ prior notice, from time to time during Borrower’s usual business hours but no more than twice a year (unless an Event of Default has occurred and is continuing), to inspect
Borrower’s Books and to make copies thereof and to check, test, and appraise the Collateral in order to verify Borrower’s financial condition or the amount, condition of, or any other matter relating to, the Collateral. 

 

	 	5.	REPRESENTATIONS AND WARRANTIES. 

 Borrower represents and warrants as follows: 
 5.1 Due Organization and
Qualification. Borrower and each Subsidiary is an entity duly existing under the laws of the jurisdiction in which it is organized and qualified and licensed to do business in any state in which the conduct of its business or its ownership of
property requires that it be so qualified, except where the failure to do so could not reasonably be expected to cause a Material Adverse Effect. 
 5.2 Due Authorization; No Conflict. The execution, delivery, and performance of the Loan Documents are within Borrower’s powers, have been duly authorized, and are not in conflict with nor
constitute a breach of any provision contained in Borrower’s organizational documents, nor will they constitute an event of default under any material agreement by which Borrower is bound. Borrower is not in default under any agreement by which
it is bound, except to the extent such default would not reasonably be expected to cause a Material Adverse Effect. 
 5.3
Collateral. Borrower has rights in or the power to transfer the Collateral, and its title to the Collateral is free and clear of Liens, adverse claims, and restrictions on transfer or pledge except for Permitted Liens. All Collateral is
located solely in the Collateral States. All Inventory is in all material respects of good and merchantable quality, free from all material defects, except for Inventory for which adequate reserves have been made. Except as set forth in the
Schedule, none of the Collateral is maintained or invested with a Person other than Bank or Bank’s Affiliates. 
 5.4
Intellectual Property. Borrower is the sole owner or licensee of the Intellectual Property, except for licenses granted by Borrower to its customers in the ordinary course of business. To the best of Borrower’s knowledge, each of the
Copyrights, Trademarks and Patents is valid and enforceable, and no part of the Intellectual Property has been judged invalid or unenforceable, in whole or in part, and no claim has been made to Borrower that any part of the Intellectual Property
violates the rights of any third party except to the extent such claim could not reasonably be expected to cause a Material Adverse Effect. 
 5.5 Name; Location of Chief Executive Office; Location of Inventory and Equipment. Except as disclosed in the Schedule, Borrower has not done business under any name other than that specified on
the signature page hereof, and its exact legal name is as set forth in the first paragraph of this Agreement. The chief executive office of Borrower is located in the Chief Executive Office 

  
 -5-

 
State at the address indicated in Section 10 hereof. Except as disclosed in the Schedule, all inventory and equipment of Borrower is located at the address indicated in Section 10
hereof and in the Collateral States at the addresses set forth in the Schedule. 
 5.6 Actions, Suits, Litigation, or
Proceedings. Except as set forth in the Schedule, there are no actions, suits, litigation or proceedings, at law or in equity, pending by or against Borrower or any Subsidiary before any court, administrative agency, or arbitrator in which a
likely adverse decision could reasonably be expected to have a Material Adverse Effect. 
 5.7 No Material Adverse Change in
Financial Statements. All consolidated and consolidating financial statements related to Borrower and any Subsidiary that are delivered by Borrower to Bank fairly present in all material respects Borrower’s consolidated and consolidating
financial condition as of the date thereof and Borrower’s consolidated and consolidating results of operations for the period then ended. There has not been a material adverse change in the consolidated or in the consolidating financial
condition of Borrower since the date of the most recent of such financial statements submitted to Bank. 
 5.8 Solvency,
Payment of Debts. Borrower is able to pay its debts (including trade debts) as they mature; the net book value of Borrower’s assets (including goodwill minus disposition costs) exceeds the fair value of its liabilities; and Borrower is not
left with unreasonably small capital after the transactions contemplated by this Agreement. 
 5.9 Compliance with Laws and
Regulations. Borrower and each Subsidiary have met the minimum funding requirements of ERISA with respect to any employee benefit plans subject to ERISA. No event has occurred resulting from Borrower’s failure to comply with ERISA that is
reasonably likely to result in Borrower’s incurring any liability that could reasonably be expected to have a Material Adverse Effect. Borrower is not an “investment company” or a company “controlled” by an “investment
company” within the meaning of the Investment Company Act of 1940. Borrower is not engaged principally, or as one of the important activities, in the business of extending credit for the purpose of purchasing or carrying margin stock (within
the meaning of Regulations T, U, and X of the Board of Governors of the Federal Reserve System). Borrower has complied in all material respects with all the provisions of the Federal Fair Labor Standards Act. Borrower is in compliance with all
environmental laws, regulations and ordinances except where the failure to comply is not reasonably likely to have a Material Adverse Effect. Borrower has not violated any statutes, laws, ordinances or rules applicable to it, the violation of which
could reasonably be expected to have a Material Adverse Effect. Borrower and each Subsidiary have filed or caused to be filed all tax returns required to be filed, and have paid, or have made adequate provision for the payment of, all taxes
reflected therein except those being contested in good faith with adequate reserves under GAAP or where the failure to file such returns or pay such taxes could not reasonably be expected to have a Material Adverse Effect. 

5.10 Subsidiaries. Borrower does not own any stock, partnership interest or other equity securities of any Person, except for
Permitted Investments. 
 5.11 Government Consents. Borrower and each Subsidiary have obtained all consents, approvals
and authorizations of, made all declarations or filings with, and given all notices to, all governmental authorities that are necessary for the continued operation of Borrower’s business as currently conducted, except where the failure to do so
would not reasonably be expected to cause a Material Adverse Effect. 
 5.12 Inbound Licenses. Except as disclosed on the
Schedule, Borrower is not a party to, nor is bound by, any inbound license or other agreement, the failure, breach, or termination of which could reasonably be expected to cause a Material Adverse Effect, or that prohibits or otherwise restricts
Borrower from granting a security interest in Borrower’s interest in such license or agreement or any other property. 

5.13 Full Disclosure. No representation, warranty or other statement made by Borrower in any certificate or written statement
furnished to Bank taken together with all such certificates and written statements furnished to Bank contains any untrue statement of a material fact or omits to state a material fact necessary in order to make the statements contained in such
certificates or statements not misleading, it being recognized by Bank that the projections and forecasts provided by Borrower in good faith and based upon reasonable assumptions are not to be viewed as facts and that actual results during the
period or periods covered by any such projections and forecasts may differ from the projected or forecasted results. 

  
 -6-

	 	6.	AFFIRMATIVE COVENANTS. 

Borrower covenants that, until payment in full of all outstanding Obligations, and for so long as Bank may have any commitment to make a
Credit Extension hereunder, Borrower shall do all of the following: 
 6.1 Good Standing and Government Compliance.
Borrower shall maintain its and each of its Subsidiaries’ organizational existence and good standing in the Borrower State, shall maintain qualification and good standing in each other jurisdiction in which the failure to so qualify could
reasonably be expected to have a Material Adverse Effect, and shall furnish to Bank the organizational identification number issued to Borrower by the authorities of the jurisdiction in which Borrower is organized, if applicable. Borrower shall
meet, and shall cause each Subsidiary to meet, the minimum funding requirements of ERISA with respect to any employee benefit plans subject to ERISA. Borrower shall comply in all material respects with all applicable Environmental Laws, and maintain
all material permits, licenses and approvals required thereunder where the failure to do so could reasonably be expected to have a Material Adverse Effect. Borrower shall comply, and shall cause each Subsidiary to comply, with all statutes, laws,
ordinances and government rules and regulations to which it is subject, and shall maintain, and shall cause each of its Subsidiaries to maintain, in force all licenses, approvals and agreements, the loss of which or failure to comply with which
would reasonably be expected to have a Material Adverse Effect. 
 6.2 Financial Statements, Reports, Certificates.
Borrower shall deliver to Bank: (i) as soon as available, but in any event within thirty (30) days after the end of each calendar month, a company prepared consolidated and consolidating balance sheet and income statement covering
Borrower’s operations during such period, in a form reasonably acceptable to Bank and certified by a Responsible Officer; (ii) as soon as available, but in any event within one hundred eighty (180) days after the end of
Borrower’s fiscal year, audited consolidated and consolidating financial statements of Borrower prepared in accordance with GAAP, consistently applied, together with an opinion which is unqualified (other than for a going concern comment or
qualification related solely to Borrower not having sufficient cash or financial resources to support 12 months of operation) or otherwise consented to in writing by Bank on such financial statements of an independent certified public accounting
firm reasonably acceptable to Bank; (iii) if applicable, copies of all statements, reports and notices sent or made available generally by Borrower to its security holders or to any holders of Subordinated Debt and all reports on Forms 10-K and
10-Q filed with the Securities and Exchange Commission; (iv) promptly upon receipt of notice thereof, a report of any legal actions pending or threatened against Borrower or any Subsidiary that could result in damages or costs to Borrower or
any Subsidiary of One Hundred Thousand Dollars ($100,000) or more; (v) promptly upon receipt, each management letter prepared by Borrower’s independent certified public accounting firm regarding Borrower’s management control systems;
(vi) as soon as available, but in any event not later than thirty (30) days from Borrower’s fiscal year end, Borrower’s financial and business projections and budget for the immediately following year, with evidence of approval
thereof by Borrower’s board of directors; and (vii) such budgets, sales projections, operating plans or other financial information generally prepared by Borrower in the ordinary course of business as Bank may reasonably request from time
to time. 
 (a) Within thirty (30) days after the last day of each month, Borrower shall deliver to Bank with the monthly
financial statements a Compliance Certificate certified as of the last day of the applicable month and signed by a Responsible Officer in substantially the form of Exhibit D hereto. 

(b) Immediately upon becoming aware of the occurrence or existence of an Event of Default hereunder, a written statement of a
Responsible Officer setting forth details of the Event of Default, and the action which Borrower has taken or proposes to take with respect thereto. 
 (c) Bank shall have a right from time to time hereafter to audit Borrower’s Accounts and appraise Collateral at Borrower’s expense, provided that such audits will be conducted no more often than
every six (6) months unless an Event of Default has occurred and is continuing. The audit cost per annum (absent an Event of Default) shall not exceed $10,000. 

  
 -7-

 Borrower may deliver to Bank on an electronic basis any certificates, reports or information
required pursuant to this Section 6.2, and Bank shall be entitled to rely on the information contained in the electronic files, provided that Bank in good faith believes that the files were delivered by a Responsible Officer. If Borrower
delivers this information electronically, it shall also deliver to Bank by U.S. Mail, reputable overnight courier service, hand delivery, facsimile or .pdf file within five (5) Business Days of submission of the unsigned electronic copy the
certification of monthly financial statements, the intellectual property report, the Borrowing Base Certificate and the Compliance Certificate, each bearing the physical signature of the Responsible Officer. 

6.3 Inventory; Returns. Borrower shall keep all Inventory in good and merchantable condition, free from all material defects
except for Inventory for which adequate reserves have been made. Returns and allowances, if any, as between Borrower and its account debtors shall be on the same basis and in accordance with the usual customary practices of Borrower, as they exist
on the Closing Date. Borrower shall promptly notify Bank of all returns and recoveries and of all disputes and claims involving more than Two Hundred Thousand Dollars ($200,000). 

6.4 Taxes. Borrower shall make, and cause each Subsidiary to make, due and timely payment or deposit of all material federal,
state, and local taxes, assessments, or contributions required of it by law, including, but not limited to, those laws concerning income taxes, F.I.C.A., F.U.T.A. and state disability, and will execute and deliver to Bank, on demand, proof
satisfactory to Bank indicating that Borrower or a Subsidiary has made such payments or deposits and any appropriate certificates attesting to the payment or deposit thereof; provided that Borrower or a Subsidiary need not make any payment if the
amount or validity of such payment is contested in good faith by appropriate proceedings and is reserved against (to the extent required by GAAP) by Borrower. 
 6.5 Insurance. 
 (a) Borrower, at its expense, shall keep the Collateral
insured against loss or damage by fire, theft, explosion, sprinklers, and all other hazards and risks, and in such amounts, as ordinarily insured against by other owners in similar businesses conducted in the locations where Borrower’s business
is conducted on the date hereof. Borrower shall also maintain liability and other insurance in amounts and of a type that are customary to businesses similar to Borrower’s. 

(b) All such policies of insurance shall be in such form, with such companies, and in such amounts as reasonably satisfactory to Bank.
All policies of property insurance shall contain a lender’s loss payable endorsement, in a form satisfactory to Bank, showing Bank as an additional loss payee, and all liability insurance policies shall show Bank as an additional insured and
specify that the insurer must give at least twenty (20) days notice to Bank before canceling its policy for any reason. Upon Bank’s request, Borrower shall deliver to Bank certified copies of the policies of insurance and evidence of all
premium payments. If no Event of Default has occurred and is continuing, proceeds payable under any casualty policy will, at Borrower’s option, be payable to Borrower to replace the property subject to the claim, provided that any such
replacement property shall be deemed Collateral in which Bank has been granted a first priority security interest. If an Event of Default has occurred and is continuing, all proceeds payable under any such policy shall, at Bank’s option, be
payable to Bank to be applied on account of the Obligations. 
 6.6 Accounts. Borrower shall, and shall cause all of its
Subsidiaries to, maintain all of its and their depository, operating accounts and cash management accounts, and its and their primary investment accounts, with Bank or Bank’s Affiliates (subject at all times to control agreements satisfactory
to Bank other than as set forth below); provided, however, that Borrower shall have until thirty (30) days after the Closing Date to complete the transfer to Bank of all account balances maintained at the other banks and financial institutions
in the accounts identified on the Schedule and to close all such accounts, and, so long as no such account is subject to a control agreement in favor of TPC during such thirty (30) day period, no control agreements will be required by Bank.

 6.7 Financial Covenants. None. 

  
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 6.8 Registration of Intellectual Property Rights. 

(a) Borrower shall register or cause to be registered on an expedited basis (to the extent not already registered) with the United
States Patent and Trademark Office or the United States Copyright Office, as the case may be, those registrable intellectual property rights now owned or hereafter developed or acquired by Borrower, to the extent that Borrower, in its reasonable
business judgment, deems it appropriate to so protect such intellectual property rights. 
 (b) Borrower shall promptly give
Bank written notice of any applications or registrations of intellectual property rights filed with the United States Patent and Trademark Office and United States Copyright Office, including the date of such filing and the registration or
application numbers, if any. 
 (c) Borrower shall give Bank prompt written notice of the filing of any applications or
registrations with the United States Copyright Office, including the title of such intellectual property rights to be registered, as such title will appear on such applications or registrations, and the date such applications or registrations will
be filed. 
 (d) Borrower shall (i) protect, defend and maintain the validity and enforceability of the Trademarks,
Patents, Copyrights, and trade secrets, (ii) use commercially reasonable efforts to detect infringements of the Trademarks, Patents and Copyrights and promptly advise Bank in writing of material infringements detected and (iii) not allow
any material Trademarks, Patents or Copyrights to be abandoned, forfeited or dedicated to the public without the written consent of Bank, which shall not be unreasonably withheld. 

6.9 Consent of Inbound Licensors. Prior to entering into or becoming bound by any material license or other similar agreement
(other than commercial off-the-shelf license agreements), Borrower shall provide written notice to Bank. 
 6.10 Reagent
Agreements. From the date hereof and going forward, Reagent Agreements entered into between Borrower and its customers and new deployments of Equipment to existing customers shall require such customer to (i) acknowledge that it has no
security interest in the Equipment located at the location at which it has been installed for such customer and (ii) acknowledge that such Equipment shall remain subject to the lien of any lender of Borrower from time to time having a perfected
security interest with respect to such Equipment. 
 6.11 Creation/Acquisition of Subsidiaries. Without
limiting the generality of any other provision hereof, in the event Borrower or any Subsidiary creates or acquires any Subsidiary, Borrower and such Subsidiary shall promptly notify Bank of the creation or acquisition of such new Subsidiary and take
all such action as may be reasonably required by Bank to cause each such Subsidiary to become a co-borrower under this Agreement, or in Bank’s sole discretion, guarantee the Obligations and, in each case, grant a continuing pledge and security
interest in and to all of the property and assets of such Subsidiary (substantially as described on Exhibit B hereto), and Borrower (or any intermediate Subsidiary holding the equity interests in such Subsidiary) shall grant and pledge to bank a
perfected security interest in the equity interests of each Subsidiary (whether foreign or domestic). 
 6.12 Further
Assurances. At any time and from time to time Borrower shall execute and deliver such further instruments and take such further action as may reasonably be requested by Bank to effect the purposes of this Agreement. 

  
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	 	7.	NEGATIVE COVENANTS. 

Borrower covenants and agrees that, so long as any credit hereunder shall be available and until the outstanding Obligations are paid in
full or for so long as Bank may have any commitment to make any Credit Extensions, Borrower will not do any of the following without Bank’s prior written consent: 
 7.1 Dispositions. Convey, sell, lease, license, transfer or otherwise dispose of (collectively, to “Transfer”), or permit any of its Subsidiaries to Transfer, all or any part of its
business or property (other than Permitted Transfers and other than for the sale of equipment by Borrower to its customers in the ordinary course of business), or subject to Section 6.6 of the Agreement, move cash balances on deposit with Bank
to accounts opened at another financial institution, other than Permitted Transfers and except that Borrower may (without consent of Bank unless an Event of Default shall have occurred and be then continuing) license or sublicense Intellectual
Property outside of the United States or for uses within the United States not currently served by Borrower, provided in each case that such license or sublicense does not result in a breach by Borrower of Section 7.2 of this Agreement.

 7.2 Change in Name, Location, Executive Office, or Executive Management; Change in Business; Change in Fiscal Year; Change
in Control. Change its name or the Borrower State or relocate its chief executive office without thirty (30) days prior written notification to Bank; replace its chief executive officer or chief financial officer without written
notification to Bank within thirty (30) days of such replacement; engage in any business, or permit any of its Subsidiaries to engage in any business, other than or reasonably related or incidental to the businesses currently engaged in by
Borrower; change its fiscal year end; have a Change in Control. 
 7.3 Mergers or Acquisitions. Merge or consolidate, or
permit any of its Subsidiaries to merge or consolidate, with or into any other business organization (other than mergers or consolidations of a Subsidiary into another Subsidiary or into Borrower), or acquire, or permit any of its Subsidiaries to
acquire, all or substantially all of the capital stock or property of another Person, or enter into any agreement to do any of the same, except where (i) such transactions do not in the aggregate exceed Two Hundred and Fifty Thousand Dollars
($250,000) during any fiscal year, (ii) no Event of Default has occurred, is continuing or would exist after giving effect to such transactions, (iii) such transactions do not result in a Change in Control, and (iv) Borrower is the
surviving entity. 
 7.4 Indebtedness. Create, incur, assume, guarantee or be or remain liable with respect to any
Indebtedness, or permit any Subsidiary so to do, other than Permitted Indebtedness, or prepay any Indebtedness or take any actions which impose on Borrower an obligation to prepay any Indebtedness, except Indebtedness to Bank. 

7.5 Encumbrances. Create, incur, assume or allow any Lien with respect to any of its property, or assign or otherwise convey any
right to receive income, including the sale of any Accounts, or permit any of its Subsidiaries so to do, except for Permitted Liens, or covenant to any other Person that Borrower in the future will refrain from creating, incurring, assuming or
allowing any Lien with respect to any of Borrower’s property. 
 7.6 Distributions. Pay any dividends or make any
other distribution or payment on account of or in redemption, retirement or purchase of any capital stock, except that Borrower may (i) repurchase the stock of former employees pursuant to stock repurchase agreements as long as an Event of
Default does not exist prior to such repurchase or would not exist after giving effect to such repurchase, and (ii) repurchase the stock of former employees pursuant to stock repurchase agreements by the cancellation of indebtedness owed by
such former employees to Borrower regardless of whether an Event of Default exists. 
 7.7 Investments. Directly or
indirectly acquire or own, or make any Investment in or to any Person, or permit any of its Subsidiaries to do so, other than Permitted Investments, or maintain or invest any of its property with a Person other than Bank or Bank’s Affiliates or
permit any Subsidiary to do so unless such Person has entered into a control agreement with Bank, in form and substance satisfactory to Bank, or suffer or permit any Subsidiary to be a party to, or be bound by, an agreement that restricts such
Subsidiary from paying dividends or otherwise distributing property to Borrower. Further, Borrower shall not enter into any license or agreement with any Prohibited Territory or with any Person organized under or doing business in a Prohibited
Territory. 
 7.8 Transactions with Affiliates. Directly or indirectly enter into or permit to exist any material
transaction with any Affiliate of Borrower (including the senior executive officers, directors, and partners of such affiliated Person) except for transactions that are in the ordinary course of Borrower’s business, upon fair and reasonable
terms that are no less favorable to Borrower than would be obtained in an arm’s length transaction with a non-affiliated Person. 

  
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 7.9 Subordinated Debt. Make any payment in respect of any Subordinated Debt, or
permit any of its Subsidiaries to make any such payment, except in compliance with the terms of such Subordinated Debt and the terms of the subordination agreement relating to such Subordinated Debt, or amend any provision of any document evidencing
such Subordinated Debt, except in compliance with the terms of the subordination agreement relating to such Subordinated Debt, or amend any provision affecting Bank’s rights contained in any documentation relating to the Subordinated Debt
without Bank’s prior written consent. 
 7.10 Inventory and Equipment. Store the Inventory or the Equipment with a
bailee, warehouseman, or similar third party unless the third party has been notified of Bank’s security interest and Bank (a) has received an acknowledgment in form acceptable to Bank from the third party that it is holding or will hold
the Inventory or Equipment for Bank’s benefit or (b) is in possession of the warehouse receipt, where negotiable, covering such Inventory or Equipment. Except for Inventory sold in the ordinary course of business and except for such other
locations as Bank may approve in writing, Borrower shall keep the Inventory and Equipment only at the location set forth in Section 10, the current Schedule, and such other locations of which Borrower gives Bank prior written notice.

 7.11 No Investment Company; Margin Regulation. Become or be controlled by an “investment company,” within
the meaning of the Investment Company Act of 1940, or become principally engaged in, or undertake as one of its important activities, the business of extending credit for the purpose of purchasing or carrying margin stock, or use the proceeds of any
Credit Extension for such purpose. 
 7.12 Gen Probe Prepayment. Make any prepayment consisting of more than ten percent
(10%) of Borrower’s current cash on hand in respect of any of the obligations owing pursuant to the Supply Agreement between Gen-Probe Incorporated and Roka Bioscience, Inc. dated May 27, 2011 (the “Gen-Probe Supply
Agreement”); at any time when (i) principal and interest payments are outstanding on loans made under that certain Loan and Security Agreement by and between Borrower and TriplePoint dated as of the date hereof (“TriplePoint
Loan Agreement” and such loans made thereunder, the “TriplePoint Loans”); and (ii) each of Paul Thomas and Steven Sobieski are no longer Chief Executive Officer and Chief Financial Officer of Borrower, respectively
(“Target Officers”). For the avoidance of doubt, the foregoing restriction shall not be applicable if (i) one of the Target Officers maintains his position as Chief Executive Officer or Chief Financial Officer of Borrower, as
applicable, (ii) Borrower has consummated its initial public offering, or (iii) no principal and interest payments on the TriplePoint Loans are outstanding. 
  

	 	8.	EVENTS OF DEFAULT. 

 Any
one or more of the following events shall constitute an Event of Default by Borrower under this Agreement: 
 8.1 Payment
Default. If Borrower fails to pay any of the Obligations when due; 
 8.2 Covenant Default. 

(a) If Borrower fails to perform any obligation under Article 6 or violates any of the covenants contained in Article 7 of this
Agreement; or 
 (b) If Borrower fails or neglects to perform or observe any other material term, provision, condition,
covenant contained in this Agreement, in any of the Loan Documents, or in any other present or future agreement between Borrower and Bank and as to any default under such other term, provision, condition or covenant that can be cured, has failed to
cure such default within twenty (20) days after Borrower receives notice thereof or any officer of Borrower becomes aware thereof; provided, however, that if the default cannot by its nature be cured within the twenty (20) day period or
cannot after diligent attempts by Borrower be cured within such twenty (20) day period, and such default is likely to be cured within a reasonable time, then Borrower shall have an additional reasonable period (which shall not in any case
exceed thirty (30) days) to attempt to cure such default, so long as Borrower continues to diligently attempt to cure such default, and within such reasonable time period the failure to have cured such default shall not be deemed an Event of
Default but no Credit Extensions will be made; 

  
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 8.3 Material Adverse Change. If there occurs any circumstance or circumstances that
could reasonably be expected to have a Material Adverse Effect. 
 8.4 Attachment. If any material portion of
Borrower’s and/or its Subsidiaries assets is attached, seized, subjected to a writ or distress warrant, or is levied upon, or comes into the possession of any trustee, receiver or person acting in a similar capacity and such attachment,
seizure, writ or distress warrant or levy has not been removed, discharged or rescinded within fifteen (15) days, or if Borrower and/or its Subsidiaries is enjoined, restrained, or in any way prevented by court order from continuing to conduct
all or any material part of its business affairs, or if a judgment or other claim becomes a lien or encumbrance upon any material portion of Borrower’s and/or its Subsidiaries assets, or if a notice of lien, levy, or assessment is filed of
record with respect to any of Borrower’s and/or its Subsidiaries assets by the United States Government, or any department, agency, or instrumentality thereof, or by any state, county, municipal, or governmental agency, and the same is not paid
within fifteen (15) days after Borrower and/or its Subsidiaries receives notice thereof, provided that none of the foregoing shall constitute an Event of Default where such action or event is stayed or an adequate bond has been posted pending a
good faith contest by Borrower and/or its Subsidiaries (provided that no Credit Extensions will be made during such cure period); 
 8.5 Insolvency. If Borrower and/or its Subsidiaries becomes insolvent, or if an Insolvency Proceeding is commenced by Borrower and/or its Subsidiaries, or if an Insolvency Proceeding is commenced
against Borrower and/or its Subsidiaries and is not dismissed or stayed within thirty (30) days (provided that no Credit Extensions will be made prior to the dismissal of such Insolvency Proceeding); 

8.6 Other Agreements. If there is a default or other failure to perform in any agreement to which Borrower and/or its Subsidiaries
is a party with a third party or parties resulting in a right by such third party or parties, whether or not exercised, to accelerate the maturity of any Indebtedness in an amount in excess of Two Hundred Thousand Dollars ($200,000) or that would
reasonably be expected to have a Material Adverse Effect; 
 8.7 Subordinated Debt. If Borrower and/or its Subsidiaries
makes any payment on account of Subordinated Debt, except to the extent the payment is allowed under any subordination agreement entered into with Bank; 
 8.8 Judgments; Settlements. If one or more (a) judgments, orders, decrees or arbitration awards requiring the Borrower and/or its Subsidiaries to pay an aggregate amount of Two Hundred
Thousand Dollars ($200,000) or greater shall be rendered against Borrower and/or its Subsidiaries other than those covered by insurance (less a reasonable deductible) for which the insurer has acknowledged coverage and the same shall not have been
vacated or stayed within thirty (30) days thereafter (provided that no Credit Extensions will be made prior to such matter being vacated or stayed); or (b) settlements is agreed upon by Borrower and/or its Subsidiaries for the payment by
Borrower and/or its Subsidiaries of an aggregate amount of Two Hundred Thousand Dollars ($200,000) or greater or that could reasonably be expected to have a Material Adverse Effect. 

8.9 Misrepresentations. If any material misrepresentation or material misstatement exists now or hereafter in any warranty or
representation set forth herein or in any certificate delivered to Bank by any Responsible Officer pursuant to this Agreement or to induce Bank to enter into this Agreement or any other Loan Document. 

 

	 	9.	BANK’S RIGHTS AND REMEDIES. 

 9.1 Rights and Remedies. Upon the occurrence and during the continuance of an Event of Default, Bank may, at its election, without notice of its election and without demand, do any one or more of
the following, all of which are authorized by Borrower: 
 (a) Declare all Obligations, whether evidenced by this Agreement, by
any of the other Loan Documents, or otherwise, immediately due and payable (provided that upon the occurrence of an Event of Default described in Section 8.5 (insolvency), all Obligations shall become immediately due and payable without any
action by Bank); 

  
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 (b) Cease advancing money or extending credit to or for the benefit of Borrower under this
Agreement or under any other agreement between Borrower and Bank; 
 (c) Settle or adjust disputes and claims directly with
account debtors for amounts, upon terms and in whatever order that Bank reasonably considers advisable; 
 (d) Make such
payments and do such acts as Bank considers necessary or reasonable to protect its security interest in the Collateral. Borrower agrees to assemble the Collateral if Bank so requires, and to make the Collateral available to Bank as Bank may
designate. Borrower authorizes Bank to enter the premises where the Collateral is located, to take and maintain possession of the Collateral, or any part of it, and to pay, purchase, contest, or compromise any encumbrance, charge, or lien which in
Bank’s determination appears to be prior or superior to its security interest and to pay all expenses incurred in connection therewith. With respect to any of Borrower’s owned premises, Borrower hereby grants Bank a license to enter into
possession of such premises and to occupy the same, without charge, in order to exercise any of Bank’s rights or remedies provided herein, at law, in equity, or otherwise; 

(e) Set off and apply to the Obligations any and all (i) balances and deposits of Borrower held by Bank, and (ii) indebtedness
at any time owing to or for the credit or the account of Borrower held by Bank; 
 (f) Ship, reclaim, recover, store, finish,
maintain, repair, prepare for sale, advertise for sale, and sell (in the manner provided for herein) the Collateral. Bank is hereby granted a license or other right, solely pursuant to the provisions of this Section 9.1, to use, without charge,
Borrower’s labels, patents, copyrights, rights of use of any name, trade secrets, trade names, trademarks, service marks, and advertising matter, or any property of a similar nature, as it pertains to the Collateral, in completing production
of, advertising for sale, and selling any Collateral and, in connection with Bank’s exercise of its rights under this Section 9.1, Borrower’s rights under all licenses and all franchise agreements shall inure to Bank’s benefit;

 (g) Sell the Collateral at either a public or private sale, or both, by way of one or more contracts or transactions, for
cash or on terms, in such manner and at such places (including Borrower’s premises) as Bank determines is commercially reasonable, and apply any proceeds to the Obligations in whatever manner or order Bank deems appropriate. Bank may sell the
Collateral without giving any warranties as to the Collateral. Bank may specifically disclaim any warranties of title or the like. This procedure will not be considered adversely to affect the commercial reasonableness of any sale of the Collateral.
If Bank sells any of the Collateral upon credit, Borrower will be credited only with payments actually made by the purchaser, received by Bank, and applied to the indebtedness of the purchaser. If the purchaser fails to pay for the Collateral, Bank
may resell the Collateral and Borrower shall be credited with the proceeds of the sale; 
 (h) Bank may credit bid and purchase
at any public sale; 
 (i) Apply for the appointment of a receiver, trustee, liquidator or conservator of the Collateral,
without notice and without regard to the adequacy of the security for the Obligations and without regard to the solvency of Borrower, any guarantor or any other Person liable for any of the Obligations; and 

(j) Any deficiency that exists after disposition of the Collateral as provided above will be paid immediately by Borrower. 

Bank may comply with any applicable state or federal law requirements in connection with a disposition of the Collateral and compliance will not be
considered adversely to affect the commercial reasonableness of any sale of the Collateral. 
 9.2 Power of Attorney.
Effective only upon the occurrence and during the continuance of an Event of Default, Borrower hereby irrevocably appoints Bank (and any of Bank’s designated officers, or employees) as Borrower’s true and lawful attorney to: (a) send
requests for verification of Accounts or notify account debtors of Bank’s security interest in the Accounts; (b) endorse Borrower’s name on any checks or other forms of payment or security that may come into Bank’s possession;
(c) sign Borrower’s 

  
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name on any invoice or bill of lading relating to any Account, drafts against account debtors, schedules and assignments of Accounts, verifications of Accounts, and notices to account debtors;
(d) dispose of any Collateral; (e) make, settle, and adjust all claims under and decisions with respect to Borrower’s policies of insurance; (f) settle and adjust disputes and claims respecting the accounts directly with account
debtors, for amounts and upon terms which Bank determines to be reasonable; and (g) file, in its sole discretion, one or more financing or continuation statements and amendments thereto, relative to any of the Collateral without the signature
of Borrower where permitted by law; provided Bank may exercise such power of attorney to sign the name of Borrower on any of the documents described in clause (g) above, regardless of whether an Event of Default has occurred. The appointment of
Bank as Borrower’s attorney in fact, and each and every one of Bank’s rights and powers, being coupled with an interest, is irrevocable until all of the Obligations have been fully repaid and performed and Bank’s obligation to provide
advances hereunder is terminated. 
 9.3 Accounts Collection. At any time after the occurrence and during the
continuation of an Event of Default, Bank may notify any Person owing funds to Borrower of Bank’s security interest in such funds and verify the amount of such Account. Borrower shall collect all amounts owing to Borrower for Bank, receive in
trust all payments as Bank’s trustee, and immediately deliver such payments to Bank in their original form as received from the account debtor, with proper endorsements for deposit. 

9.4 Bank Expenses. If Borrower fails to pay any amounts or furnish any required proof of payment due to third persons or entities,
as required under the terms of this Agreement, then Bank may do any or all of the following after reasonable notice to Borrower: (a) make payment of the same or any part thereof; or (b) obtain and maintain insurance policies of the type
discussed in Section 6.5 of this Agreement, and take any action with respect to such policies as Bank deems prudent. Any amounts so paid or deposited by Bank shall constitute Bank Expenses, shall be immediately due and payable, and shall bear
interest at the then applicable rate hereinabove provided, and shall be secured by the Collateral. Any payments made by Bank shall not constitute an agreement by Bank to make similar payments in the future or a waiver by Bank of any Event of Default
under this Agreement. 
 9.5 Bank’s Liability for Collateral. Bank has no obligation to clean up or otherwise
prepare the Collateral for sale. All risk of loss, damage or destruction of the Collateral shall be borne by Borrower. 
 9.6
No Obligation to Pursue Others. Bank has no obligation to attempt to satisfy the Obligations by collecting them from any other Person liable for them and Bank may release, modify or waive any collateral provided by any other Person to secure
any of the Obligations, all without affecting Bank’s rights against Borrower. Borrower waives any right it may have to require Bank to pursue any other Person for any of the Obligations. 

9.7 Remedies Cumulative. Bank’s rights and remedies under this Agreement, the Loan Documents, and all other agreements shall
be cumulative. Bank shall have all other rights and remedies not inconsistent herewith as provided under the Code, by law, or in equity. No exercise by Bank of one right or remedy shall be deemed an election, and no waiver by Bank of any Event of
Default on Borrower’s part shall be deemed a continuing waiver. No delay by Bank shall constitute a waiver, election, or acquiescence by it. No waiver by Bank shall be effective unless made in a written document signed on behalf of Bank and
then shall be effective only in the specific instance and for the specific purpose for which it was given. Borrower expressly agrees that this Section 9.7 may not be waived or modified by Bank by course of performance, conduct, estoppel or
otherwise. 
 9.8 Demand; Protest. Except as otherwise provided in this Agreement, Borrower waives demand, protest,
notice of protest, notice of default or dishonor, notice of payment and nonpayment and any other notices relating to the Obligations. 

  
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	 	10.	NOTICES. 

 Unless
otherwise provided in this Agreement, all notices or demands by any party relating to this Agreement or any other agreement entered into in connection herewith shall be in writing and (except for financial statements and other informational
documents which may be sent by first-class mail, postage prepaid) shall be personally delivered or sent by a recognized overnight delivery service, certified mail, postage prepaid, return receipt requested, or by telefacsimile to Borrower or to
Bank, as the case may be, at its addresses set forth below: 
  

			
	If to Borrower:	  	ROKA BIOSCIENCE, INC.
		  	20 Independence Blvd., 4th Floor
		  	Warren, New Jersey 07059
		  	Attn: Steven Sobieski, S.V.P. and C.F.O.
		  	FAX: (908) 604-2008
		
	If to Bank:	  	Comerica Bank
		  	M/C 7578
		  	39200 W. Six Mile Rd.
		  	Livonia, MI 48152
		  	Attn: National Documentation Services
		
	with a copy to:	  	Comerica Bank
		  	250 Lytton Avenue, 3rd Floor
		  	Palo Alto, California 94301
		  	Attn: Angela Ong
		  	FAX: (650) 462-6049

 The parties hereto may change the address at which they are to receive notices hereunder, by notice in
writing in the foregoing manner given to the other. 
  

	 	11.	CHOICE OF LAW AND VENUE; JURY TRIAL WAIVER. 

 This Agreement shall be governed by, and construed in accordance with, the internal laws of the State of California, without regard to principles of conflicts of law. Each of Borrower and Bank hereby
submits to the exclusive jurisdiction of the State and Federal courts located in the State of California. THE UNDERSIGNED ACKNOWLEDGE THAT THE RIGHT TO TRIAL BY JURY IS A CONSTITUTIONAL ONE, BUT THAT IT MAY BE WAIVED UNDER CERTAIN CIRCUMSTANCES. TO
THE EXTENT PERMITTED BY LAW, EACH PARTY, AFTER CONSULTING (OR HAVING HAD THE OPPORTUNITY TO CONSULT) WITH COUNSEL OF ITS, HIS OR HER CHOICE, KNOWINGLY AND VOLUNTARILY, AND FOR THE MUTUAL BENEFIT OF ALL PARTIES, WAIVES ANY RIGHT TO TRIAL BY JURY IN
THE EVENT OF LITIGATION ARISING OUT OF OR RELATED TO THIS AGREEMENT OR ANY OTHER DOCUMENT, INSTRUMENT OR AGREEMENT BETWEEN THE UNDERSIGNED PARTIES. 
  

	 	12.	REFERENCE PROVISION. 

12.1 In the event the Jury Trial Waiver set forth above is not enforceable, the parties elect to proceed under this Judicial Reference
Provision. 
 12.2 With the exception of the items specified in Section 12.3, below, any controversy, dispute or claim
(each, a “Claim”) between the parties arising out of or relating to this Agreement or any other document, instrument or agreement between the undersigned parties (collectively in this Section, the “Comerica Documents”), will be
resolved by a reference proceeding in California in accordance with the provisions of Sections 638 et seq. of the California Code of Civil Procedure (“CCP”), or their successor sections, which shall constitute the exclusive remedy for the
resolution of any Claim, including whether the Claim is subject to the reference proceeding. Except as otherwise provided in the Comerica Documents, venue for the reference proceeding will be in the Superior Court in the County where the real
property involved in the action, if any, is located or in a County where venue is otherwise appropriate under applicable law (the “Court”). 
 12.3 The matters that shall not be subject to a reference are the following: (i) foreclosure of any security interests in real or personal property, (ii) exercise of self-help remedies
(including, without limitation, set-off), (iii) appointment of a receiver and (iv) temporary, provisional or ancillary remedies (including, without limitation, writs of attachment, writs of possession, temporary restraining orders or
preliminary injunctions). This Agreement does not limit the right of any party to exercise or oppose any of the rights and remedies described in clauses (i) and (ii) or to seek or oppose from a court of competent jurisdiction any of the
items described in clauses (iii) and (iv). The exercise of, or opposition to, any of those items does not waive the right of any party to a reference pursuant to this Agreement. 

  
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 12.4 The referee shall be a retired Judge or Justice selected by mutual written agreement of
the parties. If the parties do not agree within ten (10) days of a written request to do so by any party, then, upon request of any party, the referee shall be selected by the Presiding Judge of the Court (or his or her representative). A
request for appointment of a referee may be heard on an ex parte or expedited basis, and the parties agree that irreparable harm would result if ex parte relief is not granted. 

12.5 The parties agree that time is of the essence in conducting the reference proceedings. Accordingly, the referee shall be requested,
subject to change in the time periods specified herein for good cause shown, to (i) set the matter for a status and trial-setting conference within fifteen (15) days after the date of selection of the referee, (ii) if practicable, try
all issues of law or fact within one hundred twenty (120) days after the date of the conference and (iii) report a statement of decision within twenty (20) days after the matter has been submitted for decision. 

12.6 The referee will have power to expand or limit the amount and duration of discovery. The referee may set or extend discovery
deadlines or cutoffs for good cause, including a party’s failure to provide requested discovery for any reason whatsoever. Unless otherwise ordered based upon good cause shown, no party shall be entitled to “priority” in conducting
discovery, depositions may be taken by either party upon seven (7) days written notice, and all other discovery shall be responded to within fifteen (15) days after service. All disputes relating to discovery which cannot be resolved by
the parties shall be submitted to the referee whose decision shall be final and binding. 
 12.7 Except as expressly set forth
in this Agreement, the referee shall determine the manner in which the reference proceeding is conducted including the time and place of hearings, the order of presentation of evidence, and all other questions that arise with respect to the course
of the reference proceeding. All proceedings and hearings conducted before the referee, except for trial, shall be conducted without a court reporter, except that when any party so requests, a court reporter will be used at any hearing conducted
before the referee, and the referee will be provided a courtesy copy of the transcript. The party making such a request shall have the obligation to arrange for and pay the court reporter. Subject to the referee’s power to award costs to the
prevailing party, the parties will equally share the cost of the referee and the court reporter at trial. 
 12.8 The referee
shall be required to determine all issues in accordance with existing case law and the statutory laws of the State of California. The rules of evidence applicable to proceedings at law in the State of California will be applicable to the reference
proceeding. The referee shall be empowered to enter equitable as well as legal relief, enter equitable orders that will be binding on the parties and rule on any motion which would be authorized in a court proceeding, including without limitation
motions for summary judgment or summary adjudication. The referee shall issue a decision at the close of the reference proceeding which disposes of all claims of the parties that are the subject of the reference. Pursuant to CCP § 644, such
decision shall be entered by the Court as a judgment or an order in the same manner as if the action had been tried by the Court and any such decision will be final, binding and conclusive. The parties reserve the right to appeal from the final
judgment or order or from any appealable decision or order entered by the referee. The parties reserve the right to findings of fact, conclusions of laws, a written statement of decision, and the right to move for a new trial or a different
judgment, which new trial, if granted, is also to be a reference proceeding under this provision. 
 12.9 If the enabling
legislation which provides for appointment of a referee is repealed (and no successor statute is enacted), any dispute between the parties that would otherwise be determined by reference procedure will be resolved and determined by arbitration. The
arbitration will be conducted by a retired judge or Justice, in accordance with the California Arbitration Act §1280 through §1294.2 of the CCP as amended from time to time. The limitations with respect to discovery set forth above shall
apply to any such arbitration proceeding. 
 12.10 THE PARTIES RECOGNIZE AND AGREE THAT ALL CONTROVERSIES, DISPUTES AND CLAIMS
RESOLVED UNDER THIS REFERENCE PROVISION WILL BE DECIDED BY A REFEREE AND NOT BY A JURY. AFTER CONSULTING (OR HAVING HAD THE OPPORTUNITY TO CONSULT) WITH COUNSEL OF ITS, HIS OR HER OWN CHOICE, EACH PARTY KNOWINGLY AND VOLUNTARILY, AND FOR THE MUTUAL
BENEFIT OF ALL PARTIES, 

  
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AGREES THAT THIS REFERENCE PROVISION WILL APPLY TO ANY CONTROVERSY, DISPUTE OR CLAIM BETWEEN OR AMONG THEM ARISING OUT OF OR IN ANY WAY RELATED TO, THIS AGREEMENT OR THE OTHER COMERICA DOCUMENTS.

  

	 	13.	GENERAL PROVISIONS. 

 13.1
Successors and Assigns. This Agreement shall bind and inure to the benefit of the respective successors and permitted assigns of each of the parties and shall bind all persons who become bound as a debtor to this Agreement; provided, however,
that neither this Agreement nor any rights hereunder may be assigned by Borrower without Bank’s prior written consent, which consent may be granted or withheld in Bank’s sole discretion. Bank shall have the right without the consent of or
notice to Borrower to sell, transfer, negotiate, or grant participation in all or any part of, or any interest in, Bank’s obligations, rights and benefits hereunder. 
 13.2 Indemnification. Borrower shall defend, indemnify and hold harmless Bank and its officers, employees, and agents against: (a) all obligations, demands, claims, and liabilities claimed or
asserted by any other party in connection with the transactions contemplated by this Agreement and/or the Loan Documents; and (b) all losses or Bank Expenses in any way suffered, incurred, or paid by Bank, its officers, employees and agents as
a result of or in any way arising out of, following, or consequential to transactions between Bank and Borrower whether under this Agreement, or otherwise (including without limitation reasonable attorneys fees and expenses), except for losses
caused by Bank’s gross negligence or willful misconduct. 
 13.3 Time of Essence. Time is of the essence for the
performance of all obligations set forth in this Agreement. 
 13.4 Severability of Provisions. Each provision of this
Agreement shall be severable from every other provision of this Agreement for the purpose of determining the legal enforceability of any specific provision. 
 13.5 Correction of Loan Documents. Bank may correct patent errors and fill in any blanks in this Agreement and the other Loan Documents consistent with the agreement of the parties. 

13.6 Amendments in Writing, Integration. All amendments to or terminations of this Agreement or the other Loan Documents must be
in writing signed by the parties. All prior agreements, understandings, representations, warranties, and negotiations between the parties hereto with respect to the subject matter of this Agreement and the other Loan Documents, if any, are merged
into this Agreement and the Loan Documents. 
 13.7 Counterparts. This Agreement may be executed in any number of
counterparts and by different parties on separate counterparts, each of which, when executed and delivered, shall be deemed to be an original, and all of which, when taken together, shall constitute but one and the same Agreement. 

13.8 Survival. All covenants, representations and warranties made in this Agreement shall continue in full force and effect so
long as any Obligations remain outstanding or Bank has any obligation to make any Credit Extension to Borrower. The obligations of Borrower to indemnify Bank with respect to the expenses, damages, losses, costs and liabilities described in
Section 13.2 shall survive until all applicable statute of limitations periods with respect to actions that may be brought against Bank have run. 
 13.9 Confidentiality. In handling any confidential information, Bank and all employees and agents of Bank shall exercise the same degree of care that Bank exercises with respect to its own
proprietary information of the same types to maintain the confidentiality of any non-public information thereby received or received pursuant to this Agreement except that disclosure of such information may be made (i) to the subsidiaries or
Affiliates of Bank in connection with their present or prospective business relations with Borrower, (ii) to prospective transferees, participants, or purchasers of any interest in the Obligations, (iii) as required by law, regulations,
rule or order, subpoena, judicial order or similar order, (iv) as may be required in connection with the examination, audit 

  
 -17-

 
or similar investigation of Bank, (v) to Bank’s accountants, auditors and regulators, and (vi) as Bank may determine in connection with the enforcement of any remedies hereunder.
Confidential information hereunder shall not include information that either: (a) is in the public domain or in the knowledge or possession of Bank when disclosed to Bank, or becomes part of the public domain after disclosure to Bank through no
fault of Bank; or (b) is disclosed to Bank by a third party, provided Bank does not have actual knowledge that such third party is prohibited from disclosing such information. 

[Remainder left intentionally blank. Signature page to follow.] 

  
 -18-

 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be executed as of the
date first above written. 
  

			
	ROKA BIOSCIENCE, INC.
		
	By:	 	 /s/ Steven Sobieski

	Name:	 	 Steven Sobieski

	Title:	 	 SVP and CFO

	
	COMERICA BANK
		
	By:	 	 /s/ Jeff Chapman

	Name:	 	 Jeff Chapman

	Title:	 	 SVP

 EXHIBIT A 
 DEFINITIONS 
 “Accounts” means all presently existing and hereafter arising accounts,
contract rights, payment intangibles and all other forms of obligations owing to Borrower arising out of the sale or lease of goods (including, without limitation, the licensing of software and other technology) or the rendering of services by
Borrower and any and all credit insurance, guaranties, and other security therefor, as well as all merchandise returned to or reclaimed by Borrower and Borrower’s Books relating to any of the foregoing. 

“Affiliate” means, with respect to any Person, any Person that owns or controls directly or indirectly such Person, any Person that controls or
is controlled by or is under common control with such Person. 
 “Balloon Payment” has the meaning for such term set forth in
Section 2.1(b)(ii). 
 “Bank Expenses” means all costs or expenses of Bank, or any other holder or owner of the Loan Documents
(including, without limit, court costs, legal expenses and reasonable attorneys’ fees and expenses, whether generated in-house or by outside counsel, whether or not suit is instituted, and, if suit is instituted, whether at trial court level,
appellate court level, in a bankruptcy, probate or administrative proceeding or otherwise) incurred in connection with the preparation, negotiation, execution, delivery, amendment, administration, and performance, or incurred in collecting,
attempting to collect under the Loan Documents or the Obligations, or incurred in defending the Loan Documents, or incurred in any other matter or proceeding relating to the Loan Documents or the Obligations; and reasonable Collateral audit fees.

 “Borrower State” means Delaware the state under whose laws Borrower is organized. 

“Borrower’s Books” means all of Borrower’s books and records including: ledgers; records concerning Borrower’s assets or
liabilities, the Collateral, business operations or financial condition; and all computer programs, or tape files, and the equipment, containing such information. 
 “Business Day” means any day that is not a Saturday, Sunday, or other day on which banks in the State of California are authorized or required to close. 

“Change in Control” shall mean any transaction or series of related transactions in which any “person” or “group” (within
the meaning of Section 13(d) and 14(d)(2) of the Securities Exchange Act of 1934) becomes the “beneficial owner” (as defined in Rule 13d-3 under the Securities Exchange Act of 1934), directly or indirectly, of a sufficient number of
shares of all classes of stock then outstanding of Borrower ordinarily entitled to vote in the election of directors, empowering such “person” or “group” to elect a majority of the Board of Directors of Borrower, who did not have
such power before such transaction. An initial public offering by Borrower of its common stock pursuant to which (i) Borrower’s stock will be listed on NASDAQ or another national stock exchange, and (ii) Borrower obtains gross
proceeds in an amount equal to at least Twenty Five Million Dollars ($25,000,000.00) shall not be deemed a Change of Control. 
 “Chief
Executive Office State” means New Jersey where Borrower’s chief executive office is located. 
 “Closing Date” means the
date of this Agreement. 
 “Code” means the California Uniform Commercial Code as amended or supplemented from time to time.

 “Collateral” means the property described on Exhibit B attached hereto and all Negotiable Collateral to the extent not
described on Exhibit B; except to the extent any such property (i) is nonassignable by its terms without the consent of the licensor thereof or another party (but only to the extent such prohibition on transfer is enforceable under
applicable law, including, without limitation, Sections 9406 and 9408 of the Code), or (ii) the granting of a security interest therein is contrary to applicable law, provided that upon the cessation of any such restriction or prohibition, such
property shall automatically become part of the Collateral. 

  
  

Page A-1 

 “Collateral Information Certificate” means that certain Collateral Information Certificate
completed by Borrower in the form provided to Bank as of the Closing Date. 
 “Collateral State” means the state or states where the
following states where Collateral is located, which are New Jersey, California and Tennessee. Collateral States shall not include other states in which equipment is on loan or rented to customers. 

“Contingent Obligation” means, as applied to any Person, any direct or indirect liability, contingent or otherwise, of that Person with respect
to (i) any indebtedness, lease, dividend, letter of credit or other obligation of another, including, without limitation, any such obligation directly or indirectly guaranteed, endorsed, co-made or discounted or sold with recourse by that
Person, or in respect of which that Person is otherwise directly or indirectly liable; (ii) any obligations with respect to undrawn letters of credit, corporate credit cards or merchant services issued for the account of that Person; and
(iii) all obligations arising under any interest rate, currency or commodity swap agreement, interest rate cap agreement, interest rate collar agreement, or other agreement or arrangement designed to protect a Person against fluctuation in
interest rates, currency exchange rates or commodity prices; provided, however, that the term “Contingent Obligation” shall not include endorsements for collection or deposit in the ordinary course of business. The amount of any Contingent
Obligation shall be deemed to be an amount equal to the stated or determined amount of the primary obligation in respect of which such Contingent Obligation is made or, if not stated or determinable, the maximum reasonably anticipated liability in
respect thereof as determined by such Person in good faith; provided, however, that such amount shall not in any event exceed the maximum amount of the obligations under the guarantee or other support arrangement. 

“Copyrights” means any and all copyright rights, copyright applications, copyright registrations and like protections in each work or
authorship and derivative work thereof, whether published or unpublished and whether or not the same also constitutes a trade secret, now or hereafter existing, created, acquired or held. 
 “Credit Extension” means the Growth Capital Advance or any other extension of credit by Bank to or for the benefit of Borrower hereunder. 

“Environmental Laws” means all laws, rules, regulations, orders and the like issued by any federal state, local foreign or other governmental
or quasi-governmental authority or any agency pertaining to the environment or to any hazardous materials or wastes, toxic substances, flammable, explosive or radioactive materials, asbestos or other similar materials. 

“Equipment” means all present and future machinery, equipment, tenant improvements, furniture, fixtures, vehicles, tools, parts and attachments
in which Borrower has any interest. 
 “ERISA” means the Employee Retirement Income Security Act of 1974, as amended, and the
regulations thereunder. 
 “Event of Default” has the meaning assigned in Article 8. 

“Final Payment” has the meaning for such term set forth in Section 2.5(b). 
 “GAAP” means generally accepted accounting principles, consistently applied, as in effect from time to time in the United States of America. 

“Growth Capital Advance” means a cash advance under the Growth Capital Line. 
 “Growth Capital Line” means a Credit Extension of up to Five Million Dollars ($5,000,000). 
 “Growth Capital Maturity Date” means forty-two (42) months from the Closing Date. 

“Indebtedness” means (a) all indebtedness for borrowed money or the deferred purchase price of property or services, including without
limitation reimbursement and other obligations with respect to surety bonds and letters of credit, (b) all obligations evidenced by notes, bonds, debentures or similar instruments, (c) all capital lease obligations, (d) all Contingent
Obligations, if any. 

  
  

Page A-2 

 “Insolvency Proceeding” means any proceeding commenced by or against any Person or entity under
any provision of the United States Bankruptcy Code, as amended, or under any other bankruptcy or insolvency law, including assignments for the benefit of creditors, formal or informal moratoria, compositions, extension generally with its creditors,
or proceedings seeking reorganization, arrangement, or other relief. 
 “Intellectual Property” means any copyrights, patents,
trademarks, service marks and applications therefor, now owned or hereafter acquired, or any claims for damages by way of any past, present and future infringement of any of the foregoing. 
 “Interest Only Period” means (i) the period beginning on the Closing Date and ending fifteen (15) months after the Closing Date; or (ii) if Borrower meets the Performance
Milestone, the Interest Only Period shall be the period beginning on the Closing Date and ending eighteen (18) months after the Closing Date. 
 “Inventory” means all present and future inventory in which Borrower has any interest. 

“Investment” means any beneficial ownership of (including stock, partnership or limited liability company interest or other securities) any
Person, or any loan, advance or capital contribution to any Person. 
 “IRC” means the Internal Revenue Code of 1986, as amended, and
the regulations thereunder. 
 “Letter of Credit” means a commercial or standby letter of credit or similar undertaking issued by Bank
at Borrower’s request in accordance with Section 2.1(b)(iii). 
 “Lien” means any mortgage, lien, deed of trust, charge,
pledge, security interest or other encumbrance. 
 “Loan Documents” means, collectively, this Agreement, any note or notes executed by
Borrower, and any other document, instrument or agreement entered into in connection with this Agreement, all as amended or extended from time to time. 
 “Material Adverse Effect” means (i) a material adverse change in Borrower’s prospects, business or financial condition, or (ii) a material impairment in the prospect of repayment
of all or any portion of the Obligations or in otherwise performing Borrower’s obligations under the Loan Documents, (iii) a material impairment in the perfection, value or priority of Bank’s security interests in the Collateral.

 “Negotiable Collateral” means all of Borrower’s present and future letters of credit of which it is a beneficiary, drafts,
instruments (including promissory notes), securities, documents of title, and chattel paper, and Borrower’s Books relating to any of the foregoing. 
 “Obligations” means all debt, principal, interest, Bank Expenses and other amounts owed to Bank by Borrower pursuant to this Agreement or any other agreement, whether absolute or contingent, due
or to become due, now existing or hereafter arising, including any interest that accrues after the commencement of an Insolvency Proceeding and including any debt, liability, or obligation owing from Borrower to others that Bank may have obtained by
assignment or otherwise. 
 “Patents” means all patents, patent applications and like protections including without limitation
improvements, divisions, continuations, renewals, reissues, extensions and continuations-in-part of the same. 
 “Performance
Milestone” means Bank receives evidence satisfactory to Bank that Borrower has either (i) achieved at least Ten Million Dollars ($10,000,000) in cumulative revenue for the period from the Closing Date through any date of determination
prior to September 30, 2014; or (ii) received, no later than September 30, 2014, aggregate gross cash proceeds (excluding amounts received upon conversion or cancellation of indebtedness, and excluding the proceeds described in
Section 3.1(o)) of at least Fifteen Million Dollars ($15,000,000) from the sale of additional shares of Borrower’s preferred stock whether before or after the Closing Date. 

  
  

Page A-3 

 “Periodic Payments” means all installments or similar recurring payments that Borrower may now or
hereafter become obligated to pay to Bank pursuant to the terms and provisions of any instrument, or agreement now or hereafter in existence between Borrower and Bank. 
 “Permitted Indebtedness” means: 
  

	(a)	Indebtedness of Borrower in favor of Bank arising under this Agreement or any other Loan Document; 

 

	(b)	Indebtedness existing on the Closing Date and disclosed in the Schedule; 

  

	(c)	Indebtedness not to exceed Two Hundred Thousand Dollars ($200,000) in the aggregate secured by a lien described in clause (c) of the defined term “Permitted
Liens,” provided such Indebtedness does not exceed the lesser of the cost or fair market value of the equipment financed with such Indebtedness; 

  

	(d)	Subordinated Debt; 

  

	(e)	Indebtedness to trade creditors incurred in the ordinary course of business; and 

 

	(f)	Extensions, refinancings and renewals of any items of Permitted Indebtedness, provided that the principal amount is not increased or the terms modified to impose more
burdensome terms upon Borrower or its Subsidiary, as the case may be. 

 “Permitted Investment” means: 

 

	(a)	Investments existing on the Closing Date disclosed in the Schedule; 

  

	(b)	(i) Marketable direct obligations issued or unconditionally guaranteed by the United States of America or any agency or any State thereof maturing within one
(1) year from the date of acquisition thereof, (ii) commercial paper maturing no more than one (1) year from the date of creation thereof and currently having rating of at least A-2 or P-2 from either Standard & Poor’s
Ratings Services or Moody’s Investors Service, Inc., (iii) Bank’s certificates of deposit maturing no more than one (1) year from the date of investment therein, and (iv) Bank’s money market accounts;

  

	(c)	Repurchases of stock from former employees or directors of Borrower under the terms of applicable repurchase agreements (i) in an aggregate amount not to exceed
Two Hundred Thousand Dollars ($200,000) in any fiscal year, provided that no Event of Default has occurred, is continuing or would exist after giving effect to the repurchases, or (ii) in any amount where the consideration for the repurchase is
the cancellation of indebtedness owed by such former employees to Borrower regardless of whether an Event of Default exists; 

  

	(d)	Investments accepted in connection with Permitted Transfers; 

  

	(e)	Investments of Subsidiaries in or to other Subsidiaries or Borrower and Investments by Borrower in Subsidiaries not to exceed Two Hundred Thousand Dollars ($200,000) in
the aggregate in any fiscal year; 

  

	(f)	Investments not to exceed Two Hundred Thousand Dollars ($200,000) in the aggregate in any fiscal year consisting of (i) travel advances and employee relocation
loans and other employee loans and advances in the ordinary course of business, and (ii) loans to employees, officers or directors relating to the purchase of equity securities of Borrower or its Subsidiaries pursuant to employee stock purchase
plan agreements approved by Borrower’s Board of Directors; 

  
  

Page A-4 

	(g)	Investments (including debt obligations) received in connection with the bankruptcy or reorganization of customers or suppliers and in settlement of delinquent
obligations of, and other disputes with, customers or suppliers arising in the ordinary course of Borrower’s business; 

  

	(h)	Investments consisting of notes receivable of, or prepaid royalties and other credit extensions, to customers and suppliers who are not Affiliates (including senior
executive officers, directors, and partners of such affiliated Person), in the ordinary course of business, provided that this subparagraph (h) shall not apply to Investments of Borrower in any Subsidiary; and 

 

	(i)	Joint ventures or strategic alliances in the ordinary course of Borrower’s business consisting of the non-exclusive licensing of technology, the development of
technology or the providing of technical support, provided that any cash Investments by Borrower do not exceed Two Hundred Thousand Dollars ($200,000) in the aggregate in any fiscal year. 

“Permitted Liens” means the following: 
  

	(a)	Any Liens existing on the Closing Date and disclosed in the Schedule (excluding Liens to be satisfied with the proceeds of the Growth Capital Advances) or arising under
this Agreement or the other Loan Documents; 

  

	(b)	Liens for taxes, fees, assessments or other governmental charges or levies, either not delinquent or being contested in good faith by appropriate proceedings and for
which Borrower maintains adequate reserves, provided the same have no priority over any of Bank’s security interests; 

  

	(c)	Liens securing Indebtedness not to exceed Two Hundred Thousand Dollars ($200,000) in the aggregate (i) upon or in any Equipment acquired or held by Borrower or any
of its Subsidiaries to secure the purchase price of such Equipment or indebtedness incurred solely for the purpose of financing the acquisition or lease of such Equipment, or (ii) existing on such Equipment at the time of its acquisition,
provided that the Lien is confined solely to the property so acquired and improvements thereon, and the proceeds of such Equipment; 

  

	(d)	Liens incurred in connection with the extension, renewal or refinancing of the indebtedness secured by Liens of the type described in clauses (a) through
(c) above, provided that any extension, renewal or replacement Lien shall be limited to the property encumbered by the existing Lien and the principal amount of the indebtedness being extended, renewed or refinanced does not increase; and

  

	(e)	Liens arising from judgments, decrees or attachments in circumstances not constituting an Event of Default under Sections 8.4 (attachment) or 8.8
(judgments/settlements). 

 “Permitted Transfer” means the conveyance, sale, lease, transfer or disposition by Borrower
or any Subsidiary of: 
  

	(a)	Inventory in the ordinary course of business; 

  

	(b)	Non-exclusive licenses and similar arrangements for the use of the property of Borrower or its Subsidiaries in the ordinary course of business;

  

	(c)	Worn-out or obsolete Equipment; or 

  

	(d)	Other assets of Borrower or its Subsidiaries that do not in the aggregate exceed Two Hundred Thousand Dollars ($200,000) during any fiscal year.

 “Person” means any individual, sole proprietorship, partnership, limited liability company, joint venture, trust,
unincorporated organization, association, corporation, institution, public benefit corporation, firm, joint stock company, estate, entity or governmental agency. 

  
  

Page A-5 

 “Prepayment Premium” has the meaning set forth in Section 2.1(b). 

“Pricing Addendum” means that certain Prime Referenced Rate Addendum to Loan and Security Agreement between Borrower and Bank dated as of the
Closing Date, as amended, restated, modified or supplemented from time to time. 
 “Prohibited Territory” means any person or country
listed by the Office of Foreign Assets Control of the United States Department of Treasury as to which transactions between a United States Person and that territory are prohibited. 
 “Responsible Officer” means each of the Chief Executive Officer, the Chief Operating Officer, the Chief Financial Officer and the Controller of Borrower. 

“Schedule” means the schedule of exceptions attached hereto and approved by Bank, if any. 

“SOS Reports” means the official reports from the Secretaries of State of each Collateral State, Chief Executive Office State and the Borrower
State and other applicable federal, state or local government offices identifying all current security interests filed in the Collateral and Liens of record as of the date of such report. 
 “Subordinated Debt” means any debt incurred by Borrower that is subordinated in writing to the debt owing by Borrower to Bank on terms reasonably acceptable to Bank (and identified as being such
by Borrower and Bank). 
 “Subsidiary” means any corporation, partnership or limited liability company or joint venture in which
(i) any general partnership interest or (ii) more than fifty percent (50%) of the stock, limited liability company interest or joint venture of which by the terms thereof ordinary voting power to elect the Board of Directors, managers
or trustees of the entity, at the time as of which any determination is being made, is owned by Borrower, either directly or through an Affiliate. 
 “Trademarks” means any trademark and service mark rights, whether registered or not, applications to register and registrations of the same and like protections, and the entire goodwill of the
business of Borrower connected with and symbolized by such trademarks. 
 “Warrant” means that certain Warrant to Purchase Stock
issued on the Closing Date by Borrower to Bank. 

  
  

Page A-6 

					
	DEBTOR	  	ROKA BIOSCIENCE, INC.	  	
			
	SECURED PARTY:	  	COMERICA BANK	  	

 EXHIBIT B 
 COLLATERAL DESCRIPTION ATTACHMENT TO LOAN AND SECURITY AGREEMENT 
 All personal
property of Debtor of every kind, whether presently existing or hereafter created or acquired, and wherever located, including, but not limited to: (a) all accounts (including health-care-insurance receivables), chattel paper (including
tangible and electronic chattel paper), deposit accounts, documents (including negotiable documents), equipment (including all accessions and additions thereto), financial assets, general intangibles (including payment intangibles and software),
goods (including fixtures), instruments (including promissory notes), inventory (including all goods held for sale or lease or to be furnished under a contract of service, and including returns and repossessions), investment property (including
securities and securities entitlements), letter of credit rights, money, and all of Debtor’s books and records with respect to any of the foregoing, and the computers and equipment containing said books and records; and (b) any and all
cash proceeds and/or noncash proceeds of any of the foregoing, including, without limitation, insurance proceeds, and all supporting obligations and the security therefor or for any right to payment. All terms above have the meanings given to them
in the California Uniform Commercial Code, as amended or supplemented from time to time. 
 Notwithstanding the foregoing, the
Collateral shall not include any Intellectual Property; provided, however, that the Collateral shall include all accounts and general intangibles that consist of rights to payment from the sale, licensing or disposition of all or any part of, or the
rights in, the Intellectual Property (the “Rights to Payment”). Notwithstanding the foregoing, if a judicial authority (including a U.S. Bankruptcy Court) holds that a security interest in the underlying Intellectual Property is necessary
to have a security interest in the Rights to Payment, then the Collateral shall automatically, and effective as of November 21, 2013, include the Intellectual Property to the extent necessary to permit perfection of Secured Party’s
security interest in the Rights to Payment; provided, further, other than non-exclusive licenses given in the ordinary course of Debtor’s business, in the event Debtor transfers, sells, assigns, grants a security interest in, hypothecates,
permits or suffer to exist any Lien, or otherwise transfer any interest in or encumber any portion of the Intellectual Property, either voluntarily or involuntarily, without Secured Party’s prior written consent, Secured Party’s security
interest shall include (and shall be deemed to have a Lien in such assets included from November 21, 2013) all Intellectual Property. 
 “Intellectual Property” means all of Debtor’s right, title, and interest in and to the following: 
 Copyrights, Trademarks and Patents; 
  

	 	(a)	Any and all trade secrets, and any and all intellectual property rights in computer software and computer software products now or hereafter existing, created, acquired
or held; 

  

	 	(b)	Any and all design rights which may be available to Debtor now or hereafter existing, created, acquired or held; 

 

	 	(c)	Any and all claims for damages by way of past, present and future infringement of any of the rights included above, with the right, but not the obligation, to sue for
and collect such damages for said use or infringement of the intellectual property rights identified above; and 

  

	 	(d)	All amendments, renewals and extensions of any of the Copyrights, Trademarks or Patents. 

“Copyrights” means any and all copyright rights, copyright applications, copyright registrations and like protections in each
work or authorship and derivative work thereof, whether published or unpublished and whether or not the same also constitutes a trade secret, now or hereafter existing, created, acquired or held. 

“Patents” means all patents, patent applications and like protections including without limitation improvements, divisions,
continuations, renewals, reissues, extensions and continuations-in-part of the same. 
 “Trademarks” means any
trademark and servicemark rights, whether registered or not, applications to register and registrations of the same and like protections, and the entire goodwill of the business of Debtor connected with and symbolized by such trademarks. 

 EXHIBIT C 

TECHNOLOGY & LIFE SCIENCES DIVISION 
 LOAN ANALYSIS 
 LOAN ADVANCE/PAYDOWN REQUEST FORM 

DEADLINE FOR SAME DAY PROCESSING IS 3:00* P.M, P.S.T. 
 DEADLINE FOR EQUIPMENT ADVANCES IS 3:00 P.M., P.S.T.** 
 DEADLINE FOR WIRE TRANSFERS
IS 1.30 P.M, P.S.T. 
 *At month end and the day before a holiday, the cut off time is 1:30 P.M., P.S.T. 

**Subject to 3 day advance notice. 
  

					
	TO: Loan Analysis	 	DATE:	 	TIME:
	FAX #: (650) 462-6049	 		 	

  

							
	 	 	 
	FROM:	 	 ROKA BIOSCIENCE, INC.
	  	TELEPHONE REQUEST (For Bank Use Only):
	 	 	Borrower’s Name	  	 
	FROM:	 	 	  	The following person is authorized to request the loan payment transfer/loan advance on the designated account
and is known to me.
	 	 	Authorized Signer’s Name	  		 	 
	 	 	 	  		 	 
	FROM:	 	  
	  		 	 
	 	 	Authorized Signature (Borrower)	  		 	Authorized Requester & Phone #
	PHONE #:	 	  
	  		 	 
	 	 	 	  		 	Received by (Bank) & Phone #
	FROM ACCOUNT#:	 	  
	  		 	 
	(please include Note number, if applicable)	  		 	 
	TO ACCOUNT #:	 	  
	  		 	Authorized Signature (Bank)
	(please include Note number, if
applicable)	  	 	 	 

											
	REQUESTED TRANSACTION TYPE	 	 	 	  REQUESTED DOLLAR AMOUNT	  	 	  	For Bank Use Only
	 			 	 
	PRINCIPAL INCREASE* (ADVANCE)	 	        $	 	 	  	Date Rec’d:	  	 
	PRINCIPAL PAYMENT (ONLY)	 	        $	 	 	  	Time:	  	 
	 	 		 		  		  	Comp. Status:	  	YES     NO
	OTHER INSTRUCTIONS:	 		 		  		  	Status Date:	  	 
	 	  		  	Time:	  	 
	 	  		  	Approval:	  	 
	 	  		  		  	 
	 	  	 	  	 	  	 

  

							
	
	All representations and warranties of Borrower stated in the Loan and Security Agreement are true, correct and complete in all material respects as of the date of the
telephone request for an advance confirmed by this Borrowing Certificate, including without limitation the representation that Borrower has paid for and owns the equipment financed by the Bank; provided, however, that those representations and
warranties expressly referring to another date shall be true, correct and complete in all material respects as of such date.

 

							
	
	 *  IS THERE A WIRE REQUEST TIED TO THIS LOAN ADVANCE? (PLEASE CIRCLE
ONE)    YES    NO

	
	If YES, the Outgoing Wire Transfer Instructions must be completed below.

							
	  
 OUTGOING WIRE TRANSFER INSTRUCTIONS
  
	  	  
 Fed Reference Number
  
	  	  

Bank Transfer Number
  

	 
	The items marked with an asterisk
(*) are required to be completed.
	*Beneficiary Name	  	 	  	 	  	 
	*Beneficiary Account Number	  		  		  	 
	*Beneficiary Address	  	 	  	 	  	 
	Currency Type	  	US DOLLARS ONLY
	*ABA Routing Number (9 Digits)	  	 	  	 	  	 
	*Receiving Institution Name	  		  		  	 
	*Receiving Institution Address	  	 	  	 	  	 
	*Wire Amount	  	$	  	 	  	 

 COMPLIANCE CERTIFICATE 

 

			
	Please send all Required Reporting to:	  	Comerica Bank
		  	Technology & Life Sciences Division
		  	Loan Analysis Department
		  	Fax: (650) 462-6049

  

			
	FROM:	  	ROKA BIOSCIENCE, INC.

 The undersigned authorized Officer of ROKA BIOSCIENCE, INC. (“Borrower”), hereby certifies that in accordance
with the terms and conditions of the Loan and Security Agreement between Borrower and Bank (the “Agreement”), (i) Borrower is in complete compliance for the period ending
                                        
with all required covenants, including without limitation the ongoing registration of intellectual property rights in accordance with Section 6.8, except as noted below and (ii) all representations and warranties of Borrower stated in the
Agreement are true and correct in all material respects as of the date hereof. Attached herewith are the required documents supporting the above certification. The Officer further certifies that these are prepared in accordance with Generally
Accepted Accounting Principles (GAAP) and are consistently applied from one period to the next except as explained in an accompanying letter or footnotes. 
 Please indicate compliance status by circling Yes/No under “Complies” or “Applicable” column. 
  

											
	 REPORTING COVENANTS
	 	 REQUIRED
	  	  	  	 COMPLIES
	 
					
	Company Prepared Monthly F/S	 	Monthly, within 30 days	  		  	YES	  	 	NO	  
	Compliance Certificate	 	Monthly, within 30 days	  		  	YES	  	 	NO	  
	CPA Audited, Unqualified F/S	 	Annually, within 180 days of FYE	  		  	YES	  	 	NO	  
	Annual Business Plan (incl. operating budget)	 	Annually, within 30 days of FYE	  		  	YES	  	 	NO	  
	Audit	 	Annual	  		  	YES	  	 	NO	  
					
	If Public:	 		  		  		  			
	10-Q	 	Quarterly, within 5 days of SEC filing (50 days)	  	YES	  	 	NO	  
	10-K	 	Annually, within 5 days of SEC filing (95 days)	  	YES	  	 	NO	  
					
	Total amount of Borrower’s cash and	 	Amount:
$                                        
	  		  	YES	  	 	NO	  
	investments	 		  		  		  			
	Total amount of Borrower’s cash and	 	Amount:
$                                        
	  		  	YES	  	 	NO	  
	investments maintained with Bank	 		  		  		  			
				
	  	 	 DESCRIPTION
	  	  	  	 APPLICABLE
	 
				
	Legal Action > $200,000	 	Notify promptly upon notice
                            	  	YES	  	 	NO	  
	Inventory Disputes > $200,000	 	Notify promptly upon notice
                            	  	YES	  	 	NO	  
	Mergers & Acquisitions > $250,000	 	Notify promptly upon notice
                            	  	YES	  	 	NO	  
	Cross default with other agreements	 	Notify promptly upon notice
                            	  	YES	  	 	NO	  
	>$200,000	 		  		  		  			
	Judgment > $200,000	 	Notify promptly upon notice
                            	  	YES	  	 	NO	  
				
	 FINANCIAL COVENANTS
	 	 REQUIRED
	  	 ACTUAL
	  	 COMPLIES
	 
	 None.
	 		  		  		  			
				
	 OTHER COVENANTS
	 	 REQUIRED
	  	 ACTUAL
	  	 COMPLIES
	 
					
	 Permitted Indebtedness for equipment leases
	 	<$200,000	  	
                    
 
	  	YES	  	 	NO	  
	 Permitted Investments for stock repurchase
	 	<$200,000	  	  
	  	YES	  	 	NO	  
	 Permitted Investments for subsidiaries
	 	<$200,000	  	  
	  	YES	  	 	NO	  
	 Permitted Investments for employee loans
	 	<$200,000	  	  
	  	YES	  	 	NO	  
	 Permitted Investments for joint ventures
	 	<$200,000	  	  
	  	YES	  	 	NO	  
	 Permitted Liens for equipment leases
	 	<$200,000	  	  
	  	YES	  	 	NO	  
	 Permitted Transfers
	 	<$200,000	  	  
	  	YES	  	 	NO	  

 
 Please Enter Below Comments Regarding
Violations: 
 The Officer further acknowledges that at any time Borrower is not in compliance with all the terms set forth in the Agreement,
including, without limitation, the financial covenants, no credit extensions will be made. 
  

	
	Very truly yours,
	
	  

	Authorized Signer
	
	 Name:

	
	 Title:

 SCHEDULE OF EXCEPTIONS 

TO LOAN AND SECURITY AGREEMENT 
 Permitted Indebtedness (Exhibit A) 
 The Company has an outstanding balance
payable to Gen-Probe / Hologic of $4,811,316.00 at September 30, 2013 resulting from the purchase of testing instruments. The amount due is unsecured and is non-interest bearing. The Company is required to make periodic payments to Gen-Probe
pursuant to the Supply Agreement between Gen-Probe Incorporated and Roka Bioscience, Inc. dated May 27, 2011 (the “Gen-Probe Supply Agreement”). However, for the avoidance of doubt, per the agreed-upon provisions of the final
Term Sheet with respect to this Agreement, such amount due under the Gen-Probe Supply Agreement is not to be considered “debt or sellers notes”. 
 Permitted Investments (Exhibit A) 
 None. 

Permitted Liens (Exhibit A) 
 None. 
 Prior Names (Section 5.5) 

None. 
 Inventory or
Equipment Locations (Section 5.5) 
 Roka Bioscience, Inc. 

20 Independence Boulevard, 4th Floor 
 Warren, NJ 07059 
 Roka Bioscience, Inc. 

10398 Pacific Center Court 
 San Diego, CA 92121 
 Tech Trans / Barrett Distribution, Inc. 

4836 Hickory Hill Rd. 
 Memphis, TN 38141 
 FedEx 

5025 Tuggle Rd. 

Memphis, TN 
 In
addition to the above locations, the Company has Atlas instruments on loan to customers in various states pursuant to Evaluation Agreements, Rental Agreements and Reagent Rental Agreements. Records of customer address locations are maintained by the
Company will be provided upon request. 
 Litigation (Section 5.6) 

None. 

 SCHEDULE OF EXCEPTIONS 

TO LOAN AND SECURITY AGREEMENT – Continued 

 

 Inbound Licenses (Section 5.12) 

 

	1.	License Agreement, by and between the Company and Gen-Probe, dated as of September 10, 2009. 

 

	2.	First Amendment to License Agreement, by and between the Company and Gen-Probe, effective as of May 27, 2011. 

 

	3.	License Agreement, by and between the Company and Qualigen, Inc., dated as of September 10, 2009. 

 

	4.	License Agreement, by and between the Company and PHRI Properties, Inc., dated as of September 10, 2009. 

 

	5.	Partial Assignment and Assumption and Consent Agreement, by and between the Company and Abbott Molecular Inc. (previously named Vysis, Inc.), dated as of
September 10, 2009. 

  

	6.	License Agreement, by and between the Company and Wisconsin Alumni Research Foundation dated September 30, 2011. 

 

	7.	License Agreement, by and between the Company and Oracle America, Inc. dated December 31, 2010. 

 

	8.	License Agreement, by and between the Company and Texas Tech University System dated August 8, 2013. 

 Corporation Resolutions and Incumbency Certification 

Authority to Procure Loans 

 
 I certify that I am the duly elected and qualified
Secretary of ROKA BIOSCIENCE, INC. (“Corporation”); that the following is a true and correct copy of resolutions duly adopted by the Board of Directors of the Corporation in accordance with its bylaws and applicable statutes. 

Copy of Resolutions: 
 Be it Resolved,
That: 
  

	1.	Any one (1) of the following President, CEO, CFO (insert titles only) of the Corporation are/is authorized, for, on behalf of, and in the name of the
Corporation to: 

  

	 	(a)	Negotiate and procure loans, letters of credit and other credit or financial accommodations from Comerica Bank (“Bank”), a Texas banking association, from
time to time, including without limitation that certain Loan and Security Agreement dated November     , 2013, as may be subsequently amended from time to time. 

 

	 	(b)	Discount with the Bank, commercial or other business paper belonging to the Corporation made or drawn by or upon third parties, without limit as to amount;

  

	 	(c)	Purchase, sell, exchange, assign, endorse for transfer and/or deliver certificates and/or instruments representing stocks, bonds, evidences of Indebtedness or other
securities owned by the Corporation, whether or not registered in the name of the Corporation; 

  

	 	(d)	Give security for any liabilities of the Corporation to the Bank by grant, security interest, assignment, lien, deed of trust or mortgage upon any real or personal
property, tangible or intangible of the Corporation; 

  

	 	(e)	Issue a warrant or warrants to purchase the Corporation’s capital stock; and 

 

	 	(f)	Execute and deliver in form and content as may be required by the Bank any and all notes, evidences of Indebtedness, applications for letters of credit, guaranties,
subordination agreements, loan and security agreements, financing statements, assignments, liens, deeds of trust, mortgages, trust receipts and other agreements, instruments or documents to carry out the purposes of these Resolutions, ,and any and
all amendments or modifications thereto, any or all of which may relate to all or to substantially all of the Corporation’s property and assets. 

  

	2.	Said Bank be and it is authorized and directed to pay the proceeds of any such loans or discounts as directed by the persons so authorized to sign, whether so payable
to the order of any of said persons in their individual capacities or not, and whether such proceeds are deposited to the individual credit of any of said persons or not; 

 

	3.	Any and all agreements, instruments and documents previously executed and acts and things previously done to carry out the purposes of these Resolutions are ratified,
confirmed and approved as the act or acts of the Corporation. 

  

	4.	These Resolutions shall continue in force, and the Bank may consider the holders of said offices and their signatures to be and continue to be as set forth in a
certified copy of these Resolutions delivered to the Bank, until notice to the contrary in writing is duly served on the Bank (such notice to have no effect on any action previously taken by the Bank in reliance on these Resolutions).

  

	5.	Any person, corporation or other legal entity dealing with the Bank may rely upon a certificate signed by an officer of the Bank to effect that these Resolutions and
any agreement, instrument or document executed pursuant to them are still in full force and effect and binding upon the Corporation. 

  

	6.	The Bank may consider the holders of the offices of the Corporation and their signatures, respectively, to be and continue to be as set forth in the Certificate of the
Secretary of the Corporation until notice to the contrary in writing is duly served on the Bank. 

 I further
certify that the above Resolutions are in full force and effect as of the date of this Certificate; that these Resolutions and any borrowings or financial accommodations under these Resolutions have been properly noted in the corporate books and
records, and have not been rescinded, annulled, revoked or modified; that neither the foregoing Resolutions nor any actions to be taken pursuant to them are or will be in contravention of any provision of the articles of incorporation or bylaws of
the Corporation or of any agreement, indenture or other instrument to which the Corporation is a party or by which it is bound; and that neither the articles of incorporation nor bylaws of the Corporation nor any agreement, indenture or other
instrument to which the Corporation is a party or by which it is bound require the vote or consent of shareholders of the Corporation to authorize any act, matter or thing described in the foregoing Resolutions. 

 I further certify that the following named persons have been duly elected to the offices set opposite their
respective names, that they continue to hold these offices at the present time, and that the signatures which appear below are the genuine, original signatures of each respectively: 

(PLEASE SUPPLY GENUINE SIGNATURES OF AUTHORIZED SIGNERS BELOW) 

 

					
	NAME (Type or Print)	  	TITLE	  	SIGNATURE
			
	Paul Thomas	  	President & CEO	  	/s/ Paul Thomas
			
	Steven Sobieski	  	SVP & CFO	  	/s/ Steven Sobieski
			
	  
	  	  
	  	  

			
	  
	  	  
	  	  

			
	  
	  	  
	  	  

			
	  
	  	  
	  	  

			
	  
	  	  
	  	  

 In Witness Whereof, I have affixed my name as Secretary and have caused the corporate seal (where available) of said
Corporation to be affixed on November     , 2013. 
  

	
	 /s/ Paul Thomas

	Secretary

 *** 
  

			
	The Above Statements are Correct.	  	 /s/ Steven Sobieski SVP & CFO

		  	SIGNATURE OF OFFICER OR DIRECTOR OR, IF NONE.
A SHAREHOLDER OTHER THAN SECRETARY WHEN SECRETARY IS AUTHORIZED TO SIGN
ALONE.

 Failure to complete the above when the Secretary is authorized to sign alone shall constitute a certification by the
Secretary that the Secretary is the sole Shareholder, Director and Officer of the Corporation. 

 COMERICA BANK 
 Member FDIC 
 ITEMIZATION OF AMOUNT FINANCED 

DISBURSEMENT INSTRUCTIONS 
 (Growth Capital) 
  

					
	Name(s): ROKA BIOSCIENCE, INC.	  		  	Date: November 21, 2013

  

			
	         $
	  	credited to deposit account No.                      when the Growth Capital
Advance is requested or disbursed to Borrower by cashiers check or wire transfer
	
	 Amounts paid to others on your behalf:

		
	         $7,500
	  	to Comerica Bank for Loan Fee
		
	         $
	  	to Comerica Bank for Document Fee
		
	         $
	  	to Comerica Bank for accounts receivable audit (estimate)
		
	         $
	  	to Bank counsel fees and expenses
		
	         $
	  	to                     
		
	         $
	  	to                     
		
	         $5,000,000
	  	TOTAL (AMOUNT FINANCED)

 Upon consummation of this transaction, this document will also serve as the authorization for Comerica Bank to disburse
the loan proceeds as stated above. 
  

					
	 /s/ Steven Sobieski
	 		 	  

	Signature: Steven Sobieski, CFO	 		 	Signature

  
 

 
 AUTOMATIC LOAN PAYMENT AUTHORIZATION 

 
  

					
		 	Date:	 	     November 21, 2013

  

			
	Obligor Name:	 	   ROKA BIOSCIENCE,
INC.

							
				
	Obligor Number:	 	  
	  	Lender’s Cost Center #:	 	  

			
		
	Address:	 	  

 The undersigned hereby authorizes Comerica Bank (“Bank”) to charge the account designated below for the
payments due on the loan(s) as designated below and all renewals, extensions, modifications and/or substitutions thereof. This authorization will remain in effect unless the undersigned requests a modification that is agreed to by the Bank in
writing. The undersigned remains fully responsible for all amounts outstanding to Bank if the designated account is insufficient for repayment. 
  

	 ̈	Automatic Payment Authorization for all payments on all current and future borrowings, as and when such payments come due (which payments include, without
limitation, principal, interest, fees, costs, and expenses). 

  

	 ̈	Automatic Payment Authorization for all payments on only the specific borrowing identified below, as and when such payments come due (which payments include, without
limitation, principal, interest, fees, costs, and expenses). 

  

			
	Specific Obligation Number:	 	  

  

	 ̈	Automatic Payment Authorization for less than all payments on only the specific borrowing identified below, as and when such payments come due.

  

			
	Specific Obligation Number:	 	  

  

	 	 ̈	Principal and Interest payments only 

  

	 	 ̈	Principal payments only 

  

	 	 ̈	Interest payments only 

  

	 	 ̈	SPECIAL INSTRUCTIONS/IRREGULAR PAYMENT INSTRUCTIONS 

  

 
  

 
 Payment Due Date: Your loan payments will
be charged to your account as indicated above on the dates such payments become due (or on a date thereafter when there are available funds) unless that day is a Saturday, Sunday, or Bank holiday in which case such payments will be charged on the
following business day, with interest to accrue during this extension as provided under the loan documents. 
 Account to be Charged:

  

					
	Account No.	 	  
	 	

					
			
	Transit No.	 	  
	 	

					
			
	Number of lead days to issue billing.	 	  
	 	

 (Charges to account are withdrawals pursuant to account resolution) 

 

			
	BORROWER:
	
	ROKA BIOSCIENCE, INC.
		
	By:	 	 /s/ Steven Sobieski

	Name:	 	 Steven Sobieski

	Title:	 	 SVP & CFO

  
 

 
 Agreement to Furnish Insurance 

 
 (Herein called “Bank”) 

Borrower(s): ROKA BIOSCIENCE, INC. 
 I
understand that the Security Agreement or Deed of Trust which I executed in connection with this transaction requires me to provide a physical damage insurance policy including a Lenders Loss Payable Endorsement in favor of the Bank as shown below,
within ten (10) days from the date of this agreement. 
 The following minimum insurance must be provided according to the terms of the
security documents. 
  

									
	 ̈	 	AUTOMOBILES, TRUCKS, RECREATIONAL VEHICLES	 	 ̈	  	MACHINERY & EQUIPMENT: MISCELLANEOUS PERSONAL PROPERTY
		 	   Comprehensive & Collision
	 		  	   Fire & Extended Coverage

		 	   Lender’s Loss Payable Endorsement
	 		  	   Lender’s Loss Payable Endorsement

		 		 		  	    ̈  Breach of Warranty Endorsement

				
	 ̈	 	BOATS	 	 ̈	  	AIRCRAFT
		 	   All Risk Hull Insurance
	 		  	   All Risk Ground & Flight Insurance

		 	   Lender’s Loss Payable Endorsement
	 		  	   Lender’s Loss Payable Endorsement

		 	    ̈  Breach of Warranty Endorsement
	 		  	    ̈  Breach of Warranty
Endorsement

				
	 ̈	 	MOBILE HOMES	 	 ̈	  	REAL PROPERTY
		 	   Fire, Theft & Combined Additional Coverage
	 		  	   Fire & Extended Coverage

		 	   Lender’s Loss Payable Endorsement
	 		  	   Lender’s Loss Payable Endorsement

		 	    ̈  Earthquake
	 		  	    ̈  All Risk Coverage

		 		 		  	    ̈  Special Form Risk Coverage

		 		 		  	    ̈  Earthquake

	 ̈	 	INVENTORY	 		  	    ̈  Other
	  	  

 x Other Borrower at its expense, shall keep the
Collateral insured against loss or damage by fire, theft, explosion, sprinklers, and all other hazards and risks, and in such amounts, as ordinarily insured against by other owners in similar businesses conducted in the locations where
Borrower’s business is conducted on the date hereof. Borrower shall also maintain liability and other insurance in amounts and of a type that are customary to businesses similar to Borrower’s. 

I may obtain the required insurance from any company that is acceptable to the Bank, and will deliver proof of such coverage with an effective date of
November 21, 2013 or earlier. 
 I understand and agree that if I fail to deliver proof of insurance to the Bank at the address below, or
upon the lapse or cancellation of such insurance, the Bank may procure Lender’s Single Interest Insurance or other similar coverage on the property. If the Bank procures insurance to protect its interest in the property described in the
security documents, the cost for the insurance will be added to my indebtedness as provided in the security documents. Lender’s Single Interest Insurance shall cover only the Bank’s interest as a secured party, and shall become effective
at the earlier of the funding date of this transaction or the date my insurance was canceled or expired. I UNDERSTAND THAT LENDER’S SINGLE INTEREST INSURANCE WILL PROVIDE ME WITH ONLY LIMITED PROTECTION AGAINST PHYSICAL DAMAGE TO THE
COLLATERAL, UP TO THE BALANCE OF THE LOAN, HOWEVER, MY EQUITY IN THE PROPERTY WILL NOT BE INSURED. FURTHER, THE INSURANCE WILL NOT PROVIDE MINIMUM PUBLIC LIABILITY OR PROPERTY DAMAGE INDEMNIFICATION AND DOES NOT MEET THE REQUIREMENTS OF THE
FINANCIAL RESPONSIBILITY LAW. 
 CALIFORNIA CIVIL CODE SECTION 2955.5. HAZARD INSURANCE DISCLOSURE: No lender shall require a borrower, as a
condition of receiving or maintaining a loan secured by real property, to provide hazard insurance coverage against risks to the improvements on that real property in an amount exceeding the replacement value of the improvements on the property.

  

					
		 	Bank Address for Insurance Documents:	 	
		 	 	 	
		 	 	 	
		 	 	 	
		 	Comerica Bank – Collateral Operations, Mail Code 6514	 	
		 	 	 	

 I acknowledge having read the provisions of this agreement, and agree to its terms. I authorize the Bank to
provide to any person (including any insurance agent or company) any information necessary to obtain the insurance coverage required. 
  

							
	OWNER(S) OF COLLATERAL:	 		 	DATED:	 	 November 21, 2013

				
	 /s/ Steven Sobieski
	 		 		 	
				
	 Steven Sobieski, SVP & CFO
	 		 		 	

  

									
	INSURANCE VERIFICATION	 	 
	 				 
	Date	 	  
	  		  	Phone	 	  

	 				 
	Agents Name	 	  
	  		  	Person Talked To	 	  

	 	 
	Agents Address	 	  

	 	 
	Insurance Company	 	  

	 	 	 	  	 	  	 	 	 

 USA PATRIOT ACT 

NOTICE 

OF 

CUSTOMER IDENTIFICATION 
 IMPORTANT INFORMATION ABOUT PROCEDURES FOR OPENING A NEW ACCOUNT 
 To help the
government fight the funding of terrorism and money laundering activities, Federal law requires all financial institutions to obtain, verify, and record information that identifies each person who opens an account. 

WHAT THIS MEANS FOR YOU: when you open an account, we will ask your name, address, date of birth, and other information that will allow
us to identify you. We may also ask to see your driver’s license or other identifying documents. 

 Prime Referenced Rate Addendum To 

Loan and Security Agreement 
 This Prime Referenced Rate Addendum to Loan and Security Agreement (this “Addendum”) is entered into as of November 21, 2013, by and between Comerica Bank (“Bank”) and ROKA
BIOSCIENCE, INC. (“Borrower”). This Addendum supplements the terms of the Loan and Security Agreement dated November 21, 2013 (as the same may be amended, modified, supplemented, extended or restated from time to time, collectively,
the “Agreement”). 
 1. Definitions. As used in this Addendum, the following terms shall have the following
meanings. Initially capitalized terms used and not defined in this Addendum shall have the meanings ascribed thereto in the Agreement. 
 a. “Applicable Margin” means 3.15% per annum. 
 b. “Business
Day” means any day, other than a Saturday, Sunday or any other day designated as a holiday under Federal or applicable State statute or regulation, on which Bank is open for all or substantially all of its domestic and international business
(including dealings in foreign exchange) in San Jose, California, and, in respect of notices and determinations relating the Daily Adjusting LIBOR Rate, also a day on which dealings in dollar deposits are also carried on in the London interbank
market and on which banks are open for business in London, England. 
 c. “Change in Law” means the occurrence, after
the date hereof, of any of the following: (i) the adoption or introduction of, or any change in any applicable law, treaty, rule or regulation (whether domestic or foreign) now or hereafter in effect and whether or not applicable to Bank on
such date, or (ii) any change in interpretation, administration or implementation thereof of any such law, treaty, rule or regulation by any Governmental Authority, or (iii) the issuance, making or implementation by any Governmental
Authority of any interpretation, administration, request, regulation, guideline, or directive (whether or not having the force of law), including any risk-based capital guidelines. For purposes of this definition, (x) a change in law, treaty,
rule, regulation, interpretation, administration or implementation shall include, without limitation, any change made or which becomes effective on the basis of a law, treaty, rule, regulation, interpretation administration or implementation then in
force, the effective date of which change is delayed by the terms of such law, treaty, rule, regulation, interpretation, administration or implementation, and (y) the Dodd-Frank Wall Street Reform and Consumer Protection Act (Pub. L. 111-203,
H,R. 4173) and all requests, rules, regulations, guidelines, interpretations or directives promulgated thereunder or issued in connection therewith shall be deemed to be a “Change in Law”, regardless of the date enacted, adopted, issued or
promulgated, whether before or after the date hereof, and (z) all requests, rules, guidelines or directives promulgated by the Bank for International Settlements, the Basel Committee on Banking Supervision (or any successor or similar
authority) or the United States regulatory authorities, in each case pursuant to Basel III, shall each be deemed to be a “Change in Law”, regardless of the date enacted, adopted, issued or implemented. 

d. “Daily Adjusting LIBOR Rate” means, for any day, a per annum interest rate which is equal to the quotient of the following:

	 	(1)	for any day, the per annum rate of interest determined on the basis of the rate for deposits in United States Dollars for a period equal to one (1) month appearing
on Page BBAM of the Bloomberg Financial Markets Information Service as of 8:00 a.m. (California time) (or as soon thereafter as practical) on such day, or if such day is not a Business Day, on the immediately preceding Business Day. In the event
that such rate does not appear on Page BBAM of the Bloomberg Financial Markets Information Service (or otherwise on such Service) on any day, the “Daily Adjusting LIBOR Rate” for such day shall be determined by reference to such other
publicly available service for displaying eurodollar rates as may be reasonably selected by Bank, or in the absence of such other service, the “Daily Adjusting LIBOR Rate” for such day shall, instead, be determined based upon the average
of the rates at which Bank is offered dollar deposits at or about 8:00 a.m. (California time) (or as soon thereafter as practical), on such day, or if such day is not a Business Day, on the immediately preceding Business Day, in the interbank
eurodollar market in an amount comparable to the outstanding principal amount of the Obligations and for a period equal to one (1) month; 

 divided by 
  

	 	(2)	1.00 minus the maximum rate (expressed as a decimal) on such day at which Bank is required to maintain reserves on “Euro-currency Liabilities” as defined in
and pursuant to Regulation D of the Board of Governors of the Federal Reserve System or, if such regulation or definition is modified, and as long as Bank is required to maintain reserves against a category of liabilities which includes eurodollar
deposits or includes a category of assets which includes eurodollar loans, the rate at which such reserves are required to be maintained on such category. 

 e. “Governmental Authority” means the government of the United States of America or any other nation, or of any political subdivision thereof, whether state or local, and any agency, authority,
instrumentality, regulatory body, court, central bank or other entity exercising executive, legislative, judicial, taxing, regulatory or administrative powers or functions of or pertaining to government (including, without limitation, any
supranational bodies such as the European Union or the European Central Bank). 
 f. “LIBOR Lending Office” means
Bank’s office located in the Cayman Islands, British West Indies, or such other branch of Bank, domestic or foreign, as it may hereafter designate as its LIBOR Lending Office by notice to Borrower. 

g. “Prime Rate” means the per annum interest rate established by Bank as its prime rate for its borrowers, as such rate may
vary from time to time, which rate is not necessarily the lowest rate on loans made by Bank at any such time, 
 h. “Prime
Referenced Rate” means, for any day, a per annum interest rate which is equal to the Prime Rate in effect on such day, but in no event and at no time shall the Prime Referenced Rate be less than the sum of the Daily Adjusting LIBOR Rate for

  
 -39-

 
such day plus two and one-half percent (2.50%) per annum. If, at any time, Bank determines that it is unable to determine or ascertain the Daily Adjusting LIBOR Rate for any day, the Prime
Referenced Rate for each such day shall be the Prime Rate in effect at such time, but not less than two and one-half percent (2.50%) per annum. 
 2. Interest Rate Options. Subject to the terms and conditions of this Addendum, the Obligations under the Agreement shall bear interest at the Prime Referenced Rate plus the
Applicable Margin. 
 3. Payment of Interest. Accrued and unpaid interest on the unpaid balance of the Obligations
outstanding under the Agreement shall be payable monthly, in arrears, on the first (VI) Business Day of each month, until maturity (whether as stated herein, by acceleration, or otherwise). In the event that any payment under this Addendum becomes
due and payable on any day which is not a Business Day, the due date thereof shall be extended to the next succeeding Business Day, and, to the extent applicable, interest shall continue to accrue and be payable thereon during such extension at the
rates set forth in this Addendum. Interest accruing hereunder shall be computed on the basis of a year of 360 days, and shall be assessed for the actual number of days elapsed, and in such computation, effect shall be given to any change in the
applicable interest rate as a result of any change in the Prime Referenced Rate on the date of each such change. 
 4.
Bank’s Records. The amount and date of each advance under the Agreement, its applicable interest rate, and the amount and date of any repayment shall be noted on Bank’s records, which records shall be conclusive evidence
thereof, absent manifest error; provided however, any failure by Bank to make any such notation, or any error in any such notation, shall not relieve Borrower of its obligations to repay Bank all amounts payable by Borrower to Bank under or
pursuant to this Addendum and the Agreement, when due in accordance with the terms hereof. 
 5. Default Interest
Rate. From and after the occurrence of any Event of Default, and so long as any such Event of Default remains unremedied or uncured thereafter, the Obligations outstanding under the Agreement shall bear interest at a per annum rate of five
percent (5%) above the otherwise applicable interest rate hereunder, which interest shall be payable upon demand. In addition to the foregoing, a late payment charge equal to five percent (5%) of each late payment hereunder may be charged
on any payment not received by Bank within ten (10) calendar days after the payment due date therefor, but acceptance of payment of any such charge shall not constitute a waiver of any Event of Default under the Agreement. In no event shall the
interest payable under this Addendum and the Agreement at any time exceed the maximum rate permitted by law. 
 6.
Prepayment. Borrower may prepay all or part of the outstanding balance of any Obligations at any time upon payment of the Prepayment Premium as set forth in the Agreement. Any prepayment hereunder shall also be accompanied by the
payment of all accrued and unpaid interest on the amount so prepaid. Borrower hereby acknowledges and agrees that the foregoing shall not, in any way whatsoever, limit, restrict, or otherwise affect Bank’s right to make demand for payment of
all or any part of the Obligations under the Agreement due on a demand basis in Bank’s sole and absolute discretion. 

  
 -40-

 7. Regulatory Developments or Other Circumstances Relating to the Daily Adjusting LIBOR
Rate. 
 a. If any Change in Law shall: (a) subject Bank to any tax, duty or other charge with
respect to this Addendum or any Obligations under the Agreement, or shall change the basis of taxation of payments to Bank of the principal of or interest under this Addendum or any other amounts due under this Addendum in respect thereof (except
for changes in the rate of tax on the overall net income of Bank or its LIBOR Lending Office imposed by the jurisdiction in which Bank’s principal executive office or LIBOR Lending Office is located); or (b) impose, modify or deem
applicable any reserve (including, without limitation, any imposed by the Board of Governors of the Federal Reserve System), special deposit or similar requirement against assets of, deposits with or for the account of, or credit extended by Bank,
or shall impose on Bank or the foreign exchange and interbank markets any other condition affecting this Addendum or the Obligations; and the result of any of the foregoing is to increase the cost to Bank of maintaining any part of the Obligations
or to reduce the amount of any sum received or receivable by Bank under this Addendum by an amount deemed by Bank to be material, then Borrower shall pay to Bank, within fifteen (15) days of Borrower’s receipt of written notice from Bank
demanding such compensation, such additional amount or amounts as will compensate Bank for such increased cost or reduction. A certificate of Bank, prepared in good faith and in reasonable detail by Bank and submitted by Bank to Borrower, setting
forth the basis for determining such additional amount or amounts necessary to compensate Bank shall be conclusive and binding for all purposes, absent manifest error. 
 b. In the event that any Change in Law affects or would affect the amount of capital required or expected to be maintained by Bank (or any corporation controlling Bank), and Bank determines that the
amount of such capital is increased by or based upon the existence of any obligations of Bank hereunder or the maintaining of any Obligations, and such increase has the effect of reducing the rate of return on Bank’s (or such controlling
corporation’s) capital as a consequence of such obligations or the maintaining of such Obligations to a level below that which Bank (or such controlling corporation) could have achieved but for such circumstances (taking into consideration its
policies with respect to capital adequacy), then Borrower shall pay to Bank, within fifteen (15) days of Borrower’s receipt of written notice from Bank demanding such compensation, additional amounts as are sufficient to compensate Bank
(or such controlling corporation) for any increase in the amount of capital and reduced rate of return which Bank reasonably determines to be allocable to the existence of any obligations of Bank hereunder or to maintaining any Obligations. A
certificate of Bank as to the amount of such compensation, prepared in good faith and in reasonable detail by Bank and submitted by Bank to Borrower, shall be conclusive and binding for all purposes absent manifest error. 

8. Legal Effect. Except as specifically modified hereby, all of the terms and conditions of the Agreement remain in full force and
effect. 

  
 -41-

 9. Conflicts. As to the matters specifically the subject of this Addendum, in the event
of any conflict between this Addendum and the Agreement, the terms of this Addendum shall control. 
 IN WITNESS WHEREOF,
the parties have agreed to the foregoing as of the date first set forth above. 
  

							
	 COMERICA BANK
	  	ROKA B1OSCIENCE, INC.
				
	By:	 	 /s/ Jeff Chapman
	  	By:	 	 /s/ Steven Sobieski

	Name:	 	 Jeff Chapman
	  	Name:	 	 Steven Sobieski

	Title:	 	 SVP
	  	Title:	 	 SVP and CFO

  
 -42-

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00232-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00232-of-00352.parquet"}]]