Document:

Form of Notice of Stock Option Grant

 Exhibit 10.1.1 
 TARGANTA THERAPEUTICS CORPORATION 
 2005 STOCK OPTION PLAN 
 NOTICE OF STOCK OPTION GRANT 
  

			
	Grantee’s Name and Address:	 	____________________________________________
		 	____________________________________________
		 	____________________________________________

 You have been granted an option to purchase shares of Common Stock, subject to the terms and
conditions of this Notice of Stock Option Grant (the “Notice”), the Targanta Therapeutics Corporation 2005 Stock Option Plan, as amended from time to time (the “Plan”) and the Option Agreement (the “Option
Agreement”) attached hereto, as follows. Unless otherwise defined herein, the terms defined in the Plan shall have the same defined meanings in this Notice. In the event of a conflict between the terms of the Plan and the terms of this
Notice, the terms of the Plan shall govern. 
  

			
	Grant Number	  	__________________________________
		
	Date of Grant	  	__________________________________
		
	Vesting Commencement Date	  	__________________________________
		
	Option Price per Share	  	U.S.$ _____________________________
		
	Total Number of Shares Subject to the Option (the “Shares”)	  	__________________________________
		
	Aggregate Option Price	  	U.S.$ _____________________________
		
	Type of Option:	  	___________ Incentive Stock Option
		
		  	___________ Non-Qualified Stock Option
		
	Expiration Date:	  	__________________________________
		
	Post-Termination Exercise Period:	  	Sixty (60) days after the date that Grantee’s Services terminate (if such termination is other than as a result of death or permanent and total disability or a Termination for Cause)
(provided, that, the date of termination of Service shall be the date of actual termination of Service as determined by the Company without reference to any period of notice of termination of employment to which the Grantee may be entitled at law or
pursuant to any employment agreement); and 365 days after the date that the Grantee’s Services terminate, if such termination is due to Grantee’s death or permanent and total disability); and immediately upon Termination For Cause of
Grantee’s Services.

 Vesting Schedule: 
 Subject to Grantee’s continuous Service and other limitations set forth in this Notice, the Plan and the Option Agreement, the Option may be exercised, in whole or in part, in accordance with the following
schedule: 
 25% of the Shares subject to the Option shall vest on the first of the month following the first anniversary of the Vesting
Commencement Date, and thereafter, on the first of each month thereafter in thirty-six (36) successive equal monthly installments. 
 During any authorized leave of absence, the vesting of the Option as provided in this schedule shall cease after the leave of absence exceeds a period of ninety (90) days. Vesting of the Option shall resume upon the Grantee’s
termination of the leave of absence and return to Service to the Company, a Subsidiary or an Affiliated Entity. 
 In the event of the
Grantee’s change in status from Employee to Non-employee Director or a consultant or from an Employee whose customary employment is 20 hours or more per week to an Employee whose customary employment is fewer than 20 hours per week, vesting of
the Option shall continue only to the extent determined by the Committee as of such change in status. With respect to any Incentive Stock Option that shall remain in effect after a change in status from Employee to Non-employee Director or
consultant, such Incentive Stock Option shall cease to be treated as an Incentive Stock Option and shall be treated as a Non-Qualified Stock Option on the day three (3) months and one (1) day following such change in status. 
 IN WITNESS WHEREOF, the Company and the Grantee have executed this Notice and agree that the Option is to be governed by the terms and conditions of this
Notice, the Plan, and the Option Agreement. 
  

			
	 TARGANTA THERAPEUTICS
 CORPORATION
 a Delaware corporation

		
	By:	 	  
	Title:	 	  

 THE GRANTEE ACKNOWLEDGES AND AGREES THAT THE SHARES SUBJECT TO THE OPTION SHALL VEST, IF AT ALL, ONLY DURING
THE PERIOD OF THE GRANTEE’S CONTINUOUS SERVICE (NOT THROUGH THE ACT OF BEING HIRED, BEING GRANTED THE OPTION OR ACQUIRING SHARES HEREUNDER). THE GRANTEE FURTHER ACKNOWLEDGES AND AGREES THAT NOTHING IN THIS NOTICE, THE OPTION AGREEMENT, OR THE
PLAN SHALL CONFER UPON THE GRANTEE ANY RIGHT WITH RESPECT TO FUTURE AWARDS OR CONTINUATION OF GRANTEE’S CONTINUOUS SERVICE, NOR SHALL IT INTERFERE IN ANY WAY WITH 

  

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THE GRANTEE’S RIGHT OR THE RIGHT OF THE GRANTEE’S EMPLOYER TO TERMINATE GRANTEE’S CONTINUOUS SERVICE, WITH OR WITHOUT CAUSE. 
 The Grantee acknowledges receipt of a copy of the Plan and the Option Agreement, and represents that he or she is familiar with the terms and
provisions thereof, and hereby accepts the Option subject to all of the terms and provisions hereof and thereof. The Grantee has reviewed this Notice, the Plan and the Option Agreement in their entirety, has had an opportunity to obtain the
advice of counsel prior to executing this Notice, and fully understands all provisions of this Notice, the Plan and the Option Agreement. The Grantee hereby agrees that all disputes arising out of or relating to this Notice, the Plan and the
Option Agreement shall be resolved in accordance with Article 18 of the Plan. The Grantee further agrees to notify the Company upon any change in the residence address indicated in this Notice. 
  

									
					
	Dated:	 	  	 		 	Signed:	 	  
		 		 		 		 	Grantee

  

 3Form of Stock Option Agreement

 Exhibit 10.1.2 
 TARGANTA THERAPEUTICS CORPORATION 
 2005 STOCK OPTION PLAN 
 OPTION AGREEMENT 
 1. GRANT OF OPTION. 
 (a) GENERAL TERMS. Targanta Therapeutics Corporation, a Delaware corporation (the “Company”), hereby grants to the Grantee named in the
Notice of Stock Option Grant (the “Notice”) attached to this Option Agreement (“Agreement”), an Option to purchase the total number of Shares set forth in the Notice, at the Option Price set forth in the Notice
subject to the terms, definitions and provisions of the 2005 Stock Option Plan (the “Plan”) adopted by the Company, as the same may be amended from time to time, which is incorporated in this Agreement by reference. In the event of
a conflict between the terms of the Plan and the terms of this Agreement, the terms of the Plan shall govern. Unless otherwise defined in this Agreement, the terms used in this Agreement shall have the meanings defined in the Plan. 
 (b) TAX STATUS OF OPTION FOR U.S. RESIDENTS. Unless and to the extent designated a Nonstatutory Stock Option in the Notice, this Option is intended to be
an Incentive Stock Option as defined in Section 422 of the United States Internal Revenue Code of 1986, as amended (the “Code”), to the maximum extent permitted under applicable U.S. tax law. If any portion of this Option is
designated as an Incentive Stock Option, it shall qualify as such only to the extent that the aggregate Fair Market Value of the Shares (generally, the Option’s Option Price) subject to this Option (and all other Incentive Stock Options granted
to Grantee by the Company or Subsidiary) that first become exercisable in any calendar year does not exceed US$100,000. To the extent that the aggregate Fair Market Value of such Shares exceeds US$100,000, the Shares in excess of such limit shall be
treated as a Nonstatutory Stock Option, in accordance with Article VI of the Plan. 
 2. EXERCISE OF OPTION. This Option shall be exercisable during its
term in accordance with the Vesting Schedule set out in Section 4.3 of the Plan, or as otherwise set forth in the Notice, and with the provisions of Article VII of the Plan as follows, except to the extent that the Committee in its sole and
absolute discretion may provide for acceleration of unvested options: 
 (a) RIGHT TO EXERCISE. 
 (i) This Option may not be exercised for a fraction of a share. 
 (ii) In no event may this Option be exercised after the Expiration Date of the Option as set forth in the Notice. 
 (iii) To the extent the Option is not vested at the date of termination of Service for any reason, the Option may not be exercised. For
the purposes of this clause (iii), subject to any acceleration provisions agreed to in writing between the Company and the Grantee, the date of termination of Service shall be the date of actual termination of Service as determined by the Company
without reference to any period of notice of termination of employment to which the Grantee may be entitled at law or pursuant to any employment agreement. 

 (iv) This Option is exercisable for no more than 365 days after the date that the
Grantee’s Services terminate, if such termination is due to the Grantee’s death or permanent and total disability. 
 (v) This Option is exercisable for no more than sixty (60) days after the date that Grantee’s Services terminate (other than as a result of death or permanent and total disability or a Termination for Cause) (provided, that, for this
purposes the date of termination of Service shall be the date of actual termination of Service as determined by the Company without reference to any period of notice of termination of employment to which the Grantee may be entitled at law or
pursuant to any employment agreement). 
 (vi) This Option terminates immediately upon a Termination For Cause of Service of
the Grantee’s. 
 (vii) With respect to any Incentive Stock Option that shall remain in effect after a change in status
from Employee to Non-employee Director or consultant, such Incentive Stock Option shall cease to be treated as an Incentive Stock Option and shall be treated as a Non-Qualified Stock Option on the day three (3) months and one (1) day following such
change in status. 
 (b) METHOD OF EXERCISE. 
 (i) This Option shall be exercisable by delivering to the Company an Exercise Notice in a form prescribed by the Company that shall state the election to exercise the Option, the whole number of Shares in respect of
which the Option is being exercised, and such other representations and agreements as to the holder’s investment intent with respect to such Shares of Common Stock as may be required by the Company pursuant to the provisions of the Plan. Such
written notice shall be signed by Grantee and shall be delivered in person or by certified mail to the corporate secretary of the Company. The written notice shall be accompanied by payment of the Option Price. This Option shall be deemed to be
exercised upon receipt by the Company of such written notice accompanied by the payment of the Option Price as set forth in Section 4 below. GRANTEE UNDERSTANDS AND AGREES THAT THE EXERCISE NOTICE IMPOSES CERTAIN RESTRICTIONS ON TRANSFER
(INCLUDING A MARKET STAND-OFF AGREEMENT), A RIGHT OF FIRST REFUSAL, A PLEDGE, A REPURCHASE OPTION AND A DRAG-ALONG ON THE SHARES, WHICH SHALL BE BINDING ON THE HOLDER OF THE SHARES AND ALL TRANSFEREES THEREOF. 
 (ii) As a condition to the exercise of this Option, Grantee agrees to make adequate provision for federal, state, provincial or other tax
withholding obligations, if any, which arise upon the exercise of the Option or disposition of Shares issued thereunder, whether by withholding, direct payment to the Company, or otherwise. 
  

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 (iii) No Shares shall be issued pursuant to the exercise of an Option unless such
issuance and such exercise shall comply with all relevant provisions of law and the requirements of any stock exchange upon which the Shares may then be listed. Assuming such compliance, for income tax purposes the Shares shall be considered
transferred to Grantee on the date on which the Option is exercised with respect to such Shares. 
 3. GRANTEE’S REPRESENTATIONS. In the event the
Shares purchasable pursuant to the exercise of this Option have not been registered under the Securities Act, at the time this Option is exercised, Grantee shall, if required by the Company, concurrently with the exercise of all or any portion of
this Option, deliver to the Company an investment representation statement in the customary form, a copy of which the Company will make available for Grantee’s review upon request. 
 4. METHOD OF PAYMENT. Payment of the Option Price shall be by any of the following, or a combination of the following, in the sole discretion of the Committee: 
 (a) cash, personal or cashier’s check, wire transfer to the Company, or promissory note, but only to the extent and under the terms
and conditions set forth in the Exercise Notice; 
 (b) if there is a public market for the Shares, and they are registered
under the Securities Act, and subject to the requirements of the Securities Act (Ontario) and the Ontario Rule: (a) surrender of other Shares of Common Stock of the Company, that (i) either have been owned by Grantee for more than six
(6) months on the date of surrender or were not acquired, directly or indirectly, from the Company, and (ii) have a Fair Market Value on the date of surrender equal to the aggregate Option Price of the Shares as to which the Option shall
be exercised; (b) authorization to the Company to retain from the total number of Shares as to which the Option is exercised, the number of Shares having a Fair Market value on the date of exercise equal to the aggregate Option Price for the
total number of Shares as to which the Option is exercised; or (c) delivery of a properly executed Exercise Notice together with irrevocable instructions to a broker to deliver promptly to the Company the amount of sale or loan proceeds
required to pay the aggregate Option Price. 
 5. RESTRICTIONS ON EXERCISE. 
 (a) The exercise of this Option and the issuance of the Shares upon such exercise shall be subject to compliance by the Company and Grantee with all applicable requirements of law relating thereto and with all
applicable regulations of any stock exchange (or the Nasdaq National Market, if applicable) on which the Shares may be listed for trading at the time of such exercise and issuance. 
 (b) The inability of the Company to obtain approval from any regulatory body having authority deemed by the Company to be necessary to the lawful
issuance and sale of any Shares pursuant to this Option shall relieve the Company and its directors and officers of any liability with respect to the non-issuance or sale of the Shares as to which such approval shall not have been obtained. The
Company, however, shall use its best efforts to obtain all such approvals. The Option may not be exercised until such time as the Plan has been approved by the stockholders of the Company. 
  

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 6. NON-TRANSFERABILITY OF OPTION. This Option may not be transferred in any manner otherwise than by will or by the laws
of descent or distribution to Grantee’s Immediate Family. The designation of a beneficiary does not constitute a transfer. An Option may be exercised during the lifetime of Grantee only by Grantee or a transferee permitted by this section. The
terms of this Option shall be binding upon the executors, administrators, heirs, successors and assigns of Grantee. 
 7. TERM OF OPTION. This Option may be
exercised only within the term set out in the Notice and/or the Plan, and may be exercised during such term only in accordance with the Plan and the terms of this Option. 
 8. NO ADDITIONAL EMPLOYMENT RIGHTS. Grantee understands and agrees that the vesting of Options pursuant to the Vesting Schedule is earned only by continuing as a provider of Services (not through the act of being
hired, being granted this Option or acquiring Shares). Grantee further acknowledges and agrees that nothing in this Agreement or the Plan shall confer upon Grantee any right with respect to continuation as an Employee, Non-Employee Director,
Consultant, or service provider with the Company or any Subsidiary or Affiliated Entity, nor shall it interfere in any way with his or her right to or the Company’s or any Subsidiary’s or Affiliated Entity’s right to terminate his or
her Service relationship at any time, with or without cause. 
 (a) U.S. TAX CONSEQUENCES. If Grantee is a resident of the U.S. or otherwise
subject to taxation in the U.S., Grantee acknowledges that there are certain U.S. federal tax consequences of the exercise of this Option and disposition of the Shares under the law in effect as of the date of grant. GRANTEE SHOULD CONSULT HIS OR
HER OWN TAX ADVISOR BEFORE EXERCISING THIS OPTION OR DISPOSING OF THE SHARES. 
 (b) NOTICE OF DISQUALIFYING DISPOSITION. If the Option
granted to Grantee in this Agreement is an Incentive Stock Option, and if Grantee sells or otherwise disposes of any of the Shares acquired pursuant to the Incentive Stock Option on or before the later of (i) the date two (2) years after
the Date of Grant, or (ii) the date one (1) year after transfer of such Shares to Grantee upon exercise of the Incentive Stock Option, Grantee shall notify the Company in writing within thirty (30) days after the date of any such
disposition. Grantee agrees that upon a Disqualifying Disposition, Grantee shall remit to the Company as set forth in Article XVII of the Plan the amount of any applicable federal, state, provincial and local withholding and employment taxes.

 9. SIGNATURE. This Agreement shall be deemed executed by the Company and Grantee upon execution by such parties of the Notice attached to this Agreement.

  

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