Document:

Form of Employee Matters Agreement

 EXHIBIT 10.4 
 FORM OF 
 EMPLOYEE MATTERS AGREEMENT 
 This EMPLOYEE MATTERS AGREEMENT (this “Agreement”), dated as of
[                    ], 2007, is among APP Pharmaceuticals, Inc. (formerly known as Generico Holdings, Inc.), a Delaware corporation
(“Gholdco”), APP Pharmaceuticals, LLC, a Delaware limited liability company (“Generico”) (Gholdco and Generico, collectively, the “Generico Parties”), Abraxis BioScience, LLC, a Delaware limited
liability company (“New Alpha LLC”), and New Abraxis, Inc., a Delaware corporation to be renamed Abraxis BioScience, Inc. (“New Alpha”) (New Alpha LLC and New Alpha, collectively, the “Alpha
Parties”). 
 RECITALS 
 WHEREAS, New Alpha LLC, New Alpha, Generico and Gholdco have entered into a Separation and Distribution Agreement, dated as of the date hereof (the “Separation and Distribution Agreement”); 
 WHEREAS, on the date hereof, pursuant to the Agreement and Plan of Reorganization dated as of that date (the “Holding Company Merger
Agreement”), Abraxis BioScience, Inc., a Delaware corporation (“Old Abraxis”), will merge (the “Alpha Merger”) with and into New Alpha LLC, and pursuant to the Alpha Merger, each issued and outstanding
share of common stock, $0.001 par value per share, of Old Abraxis (other than treasury shares which will be canceled and retired) will be converted into one share of common stock, par value $0.001 per share, of Gholdco (the “Gholdco Common
Stock”), with New Alpha LLC being the surviving entity in the Alpha Merger and all of its membership interests held by Gholdco; 
 WHEREAS, the following transactions will occur effective as of the date hereof after the consummation of the Alpha Merger and prior to the Distribution Time (as defined in the Separation and Distribution Agreement): 
 (a) the contribution by New Alpha LLC and the Alpha Subsidiaries (as defined in the Separation and Distribution Agreement) to Generico of all of the
Generico Assets (as defined in the Separation and Distribution Agreement), and the assumption by Generico of all of the Generico Liabilities (as defined in the Separation and Distribution Agreement), upon and subject to the terms and conditions set
forth in the Separation and Distribution Agreement (collectively, the “Generico Contribution”); 
 (b) immediately after the
Generico Contribution, the distribution by New Alpha LLC of all of the outstanding membership interests of Generico to Gholdco (the “Generico Distribution”); 
 (c) immediately after the Generico Distribution, the contribution (the “Alpha Contribution”) by Gholdco of all of the membership
interests of New Alpha LLC to New Alpha; 
 (d) simultaneously with the Alpha Contribution, the incurrence by Generico of an aggregate of $1
billion (the amount borrowed, “Borrowing Amount”) of Debt Financing (as defined in the Separation and Distribution Agreement); and 

 (e) immediately after the consummation of the Debt Financing, the distribution by Generico to Gholdco of
an amount of cash up to the Borrowing Amount (the “Generico Cash Distribution”) immediately followed by the contribution by Gholdco to New Alpha of cash in an aggregate amount of
$[            ] (the “Cash Contribution”); 
 WHEREAS,
immediately after the Cash Contribution, Gholdco will distribute (the “Share Distribution”) all of the issued and outstanding shares of common stock of New Alpha (“New Alpha Common Stock”) on a pro rata basis to the
holders of record of Gholdco Common Stock upon the terms and subject to the conditions set forth in this Agreement (the transactions described above in the two prior WHEREAS clauses, together with the Share Distribution and the other transactions
contemplated hereby, the “Transactions”); and 
 WHEREAS, in connection with the Transactions, Gholdco, Generico, New Alpha
LLC and New Alpha desire to enter into this Agreement. 
 NOW, THEREFORE, in consideration of the mutual agreements contained herein and in
the Separation and Distribution Agreement, the parties hereto agree as follows: 
 ARTICLE I 
 DEFINITIONS 
 As used in this
Agreement, the following terms shall have the meanings set forth below. Capitalized terms used but not defined herein shall have the meanings set forth in the Separation and Distribution Agreement. For purposes of this Agreement, except as provided
in Section 4.04, references to “Alpha” shall be deemed to refer to New Alpha LLC and, as applicable, its predecessor Old Abraxis. 
 1.01 “Alpha Common Stock” means the common stock, $0.001 par value per share, of Old Abraxis. 
 1.02
“Alpha Director” means each current or former member of the Board of Directors of Alpha immediately prior to the Distribution Time. 
 1.03 “Alpha Employee” means each individual who, immediately prior to the Distribution Time, is either actively employed by, or on an approved leave of absence (including short- or long-term
disability leave) from, New Alpha or any of its Subsidiaries and whose employment primarily relates to the Alpha Business. The term “Alpha Employee” shall also include any individual designated as an Alpha Employee by mutual agreement of
the parties hereto. 
 1.04 “Alpha Independent Contractor” means each independent contractor whose services primarily
relate to the Alpha Business. 
 1.05 “Alpha Option” means an option to acquire shares of Alpha Common Stock granted
pursuant to an Alpha Option Plan. 
  

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 1.06 “Alpha Option Plan” means the American Pharmaceutical Partners, Inc. 2001
Stock Incentive Plan and the American Pharmaceutical Partners, Inc. 1997 Stock Option Plan. 
 1.07 “Alpha Personnel”
means the Alpha Employees and the Former Alpha Employees. Except where context dictates otherwise, references to the Alpha Personnel shall be deemed to include references to the estates, legal representatives, dependents and beneficiaries of the
Alpha Personnel. 
 1.08 “Alpha Restricted Stock Unit” means each restricted stock unit denominated in shares of
Alpha Common Stock granted under the American BioScience, Inc. Restricted Stock Unit Plan I, the American BioScience, Inc. Restricted Stock Unit Plan II and the American Pharmaceutical Partners, Inc. 2001 Stock Incentive Plan. 
 1.09 “Benefit Plans” means, collectively, the Pension Plans, the Welfare Plans and the Non-ERISA Benefit Arrangements (including,
for avoidance of doubt, the Non-U.S. Benefit Plans). 
 1.10 “COBRA” means the Consolidated Omnibus Budget
Reconciliation Act of 1985, as codified at Part 6 of Subtitle B of Title I of ERISA and at Section 4980B of the Code. 
 1.11
“Code” means the U.S. Internal Revenue Code of 1986, as amended. 
 1.12 “Employee Agreement”
means those agreements to which the Alpha Personnel or the Generico Personnel, on the one hand, and Gholdco or any of its Subsidiaries, on the other hand, are parties that contain confidentiality, noncompetition, nonsolicitation, assignment of
inventions or other similar covenants, but shall not include any Employment Agreement. 
 1.13 “Employment Agreement”
means any agreement to which the Alpha Personnel or the Generico Personnel, on the one hand, and Gholdco or any of its Subsidiaries, on the other hand, are parties to the extent guaranteeing or otherwise agreeing to wages, salary, bonuses, severance
payments or other benefits or forms of compensation. 
 1.14 “ERISA” means the Employee Retirement Income Security
Act of 1974, as amended, 29 U.S.C. §1001, et seq. 
 1.15 “Former Alpha Employee” means each
individual whose employment with Alpha and its Subsidiaries was terminated prior to the Distribution Time and whose employment, at the time of his or her separation from service, primarily related to the Alpha Business as determined in accordance
with Section 2.01(b). 
 1.16 “Former Generico Employee” means each individual whose employment with Alpha and
its Subsidiaries was terminated prior to the Distribution Time and whose employment, at the time of his or her separation from service, primarily related to the Generico Business as determined in accordance with Section 2.01(b). 
 1.17 “Generico Contribution” has the meaning set forth in the Separation and Distribution Agreement. 
  

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 1.18 “Generico Employee” means each individual who, immediately prior to the
Distribution Time, is either actively employed by, or on an approved leave of absence (including short- or long-term disability leave) from, Alpha or any of its Subsidiaries and whose employment primarily relates to the Generico Business. The term
“Generico Employee” shall also include any individual designated as a Generico Employee by mutual agreement of the parties hereto. 
 1.19 “Generico Independent Contractor” means each individual or personal services corporation providing independent contractor services to Alpha or any of its Subsidiaries and whose services primarily relate to the
Generico Business. 
 1.20 “Generico Personnel” means the Generico Employees and the Former Generico Employees.
Except where context dictates otherwise, references to the Generico Personnel shall be deemed to include references to the estates, legal representatives, dependents and beneficiaries of the Generico Personnel. 
 1.21 “Gholdco Director” means any Alpha Director who is a director of Gholdco immediately after the Distribution Time.

 1.22 “Gholdco Option” means an option to acquire shares of Gholdco Common Stock converted from an Alpha Option, as
provided in Section 4.04(a). 
 1.23 “Gholdco Restricted Stock Unit” means a restricted stock unit denominated
in shares of Gholdco Common Stock converted from an Alpha Restricted Stock Unit as provided in Section 4.04(c)(i) or (iii). 
 1.24
“IRS” means the U.S. Internal Revenue Service. 
 1.25 “Jointly Employed Employee” means the
individuals who Gholdco and New Alpha determine will be employed, immediately following the Distribution Time, by a member of the Alpha Group and a member of the Generico Group. The parties agree that the sole Jointly Employed Employees will be
Patrick Soon-Shiong and Lisa Gopala. 
 1.26 “New Alpha Director” means any Alpha Director who is a director of New
Alpha immediately after the Distribution Time. 
 1.27 “New Alpha Option” means an option to acquire shares of New
Alpha Common Stock converted from an Alpha Option, as provided in Section 4.04(b). 
 1.28 “New Alpha Restricted Stock
Unit” means a restricted stock unit denominated in shares of New Alpha Common Stock converted from a Alpha Restricted Stock Unit, as provided in Section 4.04(c)(ii) or (iv). 
 1.29 “Non-ERISA Benefit Arrangement” means each contract, agreement, policy, practice, program, plan, trust or arrangement of
Gholdco or any of its Subsidiaries, other than a Pension Plan or Welfare Plan, providing for benefits, perquisites or compensation of any nature to the Alpha Personnel or the Generico Personnel, including, without limitation severance, 

  

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tuition reimbursement, supplemental unemployment, vacation, sick, personal or bereavement days, holidays, bonus, stock-based compensation or other forms of
incentive compensation. 
 1.30 “Non-U.S. Benefit Plan” means each employee benefit plan, policy, program or
arrangement sponsored or maintained by the Alpha Group or the Generico Group that is sponsored or maintained primarily for the benefit of employees located outside of the United States. 
 1.31 “Pension Plan” means any pension plan (as defined in section 3(2) of ERISA). 
 1.32 “Transition Services Agreement” means the Transition Services Agreement, dated as of the date hereof, between New Alpha and
Gholdco. 
 1.33 “U.S.” means the United States of America. 
 1.34 “Welfare Plan” means any employee welfare plan (as defined in section 3(1) of ERISA), but excluding any severance pay plan.

 ARTICLE II 
 EMPLOYEE
MATTERS 
 2.01 Allocation of Employment of Alpha Employees and Generico Employees. 
 (a) Subject to Section 2.01(c), effective as of immediately prior to the Distribution Time, (i) the employment of each Generico Employee shall
be transferred to (or such individual shall remain an employee of, as applicable) Generico and/or another member of the Generico Group as determined by Gholdco, and (ii) the employment of each Alpha Employee shall be transferred to (or such
individual shall remain an employee of, as applicable) New Alpha LLC and/or another member of the Alpha Group as determined by New Alpha. From and after the Distribution Time, each Alpha Employee shall remain an employee of the Alpha Group and each
Generico Employee shall remain an employee of the Generico Group; provided that nothing contained herein shall be construed to limit the ability of any member of the Alpha Group or Generico Group to terminate the employment of any of its employees
at any time and for any or no reason. In addition, (i) no provision of this Agreement shall be construed to apply to any individual who is hired after the Distribution Time by the Alpha Group and (ii) no provision of this Agreement shall
be construed to apply to any individual who is hired after the Distribution Time by the Generico Group, in each case except to the extent such individual is a Former Alpha Employee or a Former Generico Employee and, in such case, only with respect
to the period of employment with Alpha and its Subsidiaries prior to the Distribution Time. 
 (b) Those employees who provide services in
respect of both the Alpha Business and the Generico Business (the “Shared Services Employees”) have been designated as Alpha Employees or Generico Employees by mutual agreement of the parties. 
 (c) Effective immediately prior to the Distribution Time, Jointly Employed Employees shall be employed by a member of the Alpha Group and a member of the
Generico Group as determined by New Alpha and Gholdco. With the exception of salary and cash bonus, 

  

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each Jointly Employed Employee will participate in the Benefit Plans only of the Alpha Group (and in none of the Benefit Plans of the Generico Group). The
salary and cash bonus payments made to a Jointly Employed Employee by the Alpha Group shall be reduced by any salary and bonus paid to a jointly Employed Employee by the Generico Group. 
 2.02 Severance Obligations. 
 (a) It is intended that the Alpha Personnel and the Generico Personnel shall not be entitled to any termination or severance benefits as a result of the Alpha Merger, the Generico Distribution, the Share Distribution or any other
transaction contemplated by this Agreement or the Separation and Distribution Agreement (other than payments or benefits with respect to any such individuals who separate from service in connection with such transactions and are entitled to a
termination or severance benefit under applicable legislation, which shall be the responsibility of New Alpha if the payment or benefit is payable to an Alpha Personnel, and shall be the responsibility of Generico if the payment or benefit is
payable to a Generico Personnel), and each of the Alpha Parties and the Generico Parties shall cause the severance arrangements of the Alpha Group and the Generico Group, respectively, to be interpreted and administered consistent with such intent.

 (b) Except as set forth in Section 2.02(a), from and after the Distribution Time, the Generico Parties shall be fully responsible
for, and none of the Alpha Parties or any of the Affiliates of the Alpha Parties shall have any Liability or other obligation for, any termination or severance payment or benefit obligations with respect to any of the Generico Personnel (or any
person who becomes an employee of any member of the Generico Group after the Distribution Time) payable after the Distribution Time, including any severance payments owed, but not yet paid, to any Former Generico Employee. 
 (c) From and after the Distribution Time, the Alpha Parties shall be fully responsible for, and none of the Generico Parties or any of the Affiliates of
the Generico Parties shall have any Liability or other obligations for, any termination or severance payments or benefit obligations with respect to any of the Alpha Personnel (or any person who becomes an employee of any member of the Alpha Group
after the Distribution Time) payable after the Distribution Time, including any severance payments owed, but not yet paid, to any Former Alpha Employee. 
 2.03 Personnel Records. 
 (a) Subject to Applicable Laws, as soon as practicable following the
Distribution Time, the Alpha Parties shall cause all information and records regarding employment and personnel matters of the Generico Personnel in the possession of the Alpha Group (including, without limitation, all Employee Agreements) to be
transferred to a member of the Generico Group designated by Generico, and the Generico Parties shall cause the members of the Generico Group to retain such information and records after the Distribution Time in accordance in all material respects
with Applicable Laws relating to the collection, storage, retention and disclosure of such information and records. From and after such transfer, such information and records shall be the property of the Generico Group. Subject to Applicable Laws,
New Alpha 

  

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and its Subsidiaries shall be entitled to retain copies of any such information and records with respect to any of the Generico Personnel so transferred to
the Generico Group in which New Alpha or any of its Subsidiaries has an interest, as determined by New Alpha in its reasonable discretion. Access to such information and records after the Distribution Time will be provided to the Alpha Parties in
accordance with Article VI of the Separation and Distribution Agreement. Notwithstanding any limitations and restrictions set forth in Article VI of the Separation and Distribution Agreement, the Alpha Parties shall be entitled to
reasonable access, subject to Applicable Laws, to such information and records necessary to their or their Subsidiaries’ administration of any Benefit Plans sponsored or maintained by any member of the Alpha Group or as otherwise required by
Applicable Laws. 
 (b) Subject to Applicable Laws, all information and records regarding employment and personnel matters of the Alpha
Personnel shall be retained after the Distribution Time by members of the Alpha Group in accordance in all material respects with Applicable Laws relating to the collection, storage, retention and disclosure of such information and records. Access
to such information and records after the Distribution Time will be provided to Generico in accordance with Article VI of the Separation and Distribution Agreement. Notwithstanding any limitations and restrictions set forth in Article
VI of the Separation and Distribution Agreement, Generico shall be entitled to reasonable access, subject to Applicable Laws, to such information and records necessary to Generico’s administration of any Benefit Plans on behalf of any of
the Alpha Parties or on behalf or for the benefit of any Alpha Personnel after the Distribution Time or as otherwise required by Applicable Laws for so long as said administration continues pursuant to this Agreement, the Transition Services
Agreement or such longer period as required by Applicable Laws. Subject to Applicable Laws, New Alpha shall also provide Gholdco or any of its Subsidiaries upon request with copies of any such information and records with respect to any of the Alpha
Personnel in which Gholdco or any of its Subsidiaries has an interest, as determined by Generico in its reasonable discretion. 
 ARTICLE
III 
 WELFARE PLANS 
 3.01 Assumption of Welfare Plans by the Generico Group; Cessation of Participation in Welfare Plans. 
 (a) Effective
as of the Distribution Time, the Generico Group shall assume the Welfare Plans immediately prior to the Distribution Time that are sponsored by Alpha or any of its Subsidiaries (prior to such assumption, the “Alpha Welfare Plans”),
including all Liabilities thereunder (following such assumption, the “Generico Welfare Plans”). 
 (b) Each member of the
Alpha Group shall cease to be a participating employer in all Generico Welfare Plans at the Distribution Time, and participation in the Generico Welfare Plans will cease for all Alpha Personnel at the Distribution Time. 
 3.02 New Alpha Welfare Plans. To the extent applicable to any Welfare Plans sponsored by any member of the Alpha Group in which Alpha
Personnel commence to participate after the Distribution Time that provide benefits similar to the benefits that had been 

  

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provided to such employees under an Alpha Welfare Plan immediately prior to the Distribution Time (each, a “New Alpha Welfare Plan”), New
Alpha LLC shall use its reasonable best efforts to cause the New Alpha Welfare Plans to recognize all coverage and contribution elections made by Alpha Personnel under the Generico Welfare Plans in effect for the period immediately prior to the
commencement of participation and shall apply such elections under the New Alpha Welfare Plans for the remainder of the period or periods for which such elections are by their terms applicable. New Alpha LLC shall cause all beneficiary designations
made by Alpha Personnel under the Generico Welfare Plans to the extent applicable, to be transferred to, and be in full force and effect under, the New Alpha Welfare Plans until such beneficiary designations are replaced or revoked by the Alpha
Personnel who made the beneficiary designation. 
 3.03 Welfare Plan Liabilities. 
 (a) Liabilities under New Alpha Welfare Plans. The Alpha Parties shall be solely jointly and severally responsible for all Liabilities incurred
with respect to any Alpha Personnel or otherwise under the New Alpha Welfare Plans, and none of the Generico Parties or the Generico Welfare Plans shall assume, retain or become responsible for any such Liabilities. 
 (b) Liabilities under Generico Welfare Plans; Incurred but Unreported Claims. New Alpha LLC shall be solely responsible, after the Distribution
Time, for all claims for welfare benefits (and for any Liabilities arising as a result of such claims) incurred by any of the Alpha Personnel under the Generico Welfare Plans following the Distribution Time, and New Alpha LLC shall promptly
reimburse Generico and the Generico Welfare Plans for all such claims and Liabilities (except to the extent that Generico is fully reimbursed for such Liability by insurance with third-party insurers). In addition, New Alpha LLC shall be solely
responsible, after the Distribution Time, for all claims for welfare benefits (and for any Liabilities arising as a result of such claims) incurred by any of the Alpha Personnel under the Generico Welfare Plans at or prior to the Distribution Time,
except to the extent that such claims have been paid as of the Distribution Time or to the extent that Generico is fully reimbursed by insurance with third-party insurers, and neither Generico nor the Generico Welfare Plans shall assume or retain
any such claims or Liabilities (except that (i) the Generico Welfare Plans shall bear the responsibility of determining whether such claims are entitled to payment under the terms of the Generico Welfare Plans as provided in the Transition
Services Agreement and (ii) if, to the extent necessary for the efficient administration of the Generico Welfare Plans, Generico pays any of such claims, Generico shall be promptly reimbursed therefor by New Alpha LLC). Claims for health
benefits shall be considered to be incurred prior to the Distribution Time if the services related to such claims were provided prior to the Distribution Time. Claims for all other welfare benefits shall be considered to be incurred prior to the
Distribution Time if the date of loss occurred prior to the Distribution Time. 
 (c) Short-Term and Long-Term Disability Benefits.
Notwithstanding subsection (a) and (b) above, all Alpha Personnel who, as of the Distribution Time, are receiving or entitled to receive short-term or long-term disability benefits under a Generico short- and long-term disability plan
(which is a Generico Welfare Plan) with respect to the incurrence of a disability on or prior to the Distribution Time shall continue participation or become eligible to participate in the applicable Generico short- and long-term disability plans
following the Distribution Time 

  

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in accordance with the terms and conditions of such plans and any applicable related insurance contracts or policies; provided, however, that (i) New
Alpha LLC shall bear and be responsible for all costs, claims and other Liabilities related to the provision of short-term disability benefits and medical benefits to such Alpha Personnel during their disability period from and after the
Distribution Time under the applicable Generico Welfare Plans (other than Liabilities related to such plans that result from matters of non-compliance following the Distribution Time; provided that in no event shall the continued participation by
Alpha Personnel in the Generico Welfare Plans as described herein constitute or be deemed to constitute a matter of non-compliance for these purposes) and (ii) neither Generico nor any of the Generico Welfare Plans shall be obligated to provide
medical benefits to such Alpha Personnel during their disability period following the date on which New Alpha LLC establishes the New Alpha Welfare Plans that provide medical benefits to the Alpha Employees. 
 (d) COBRA and HIPAA Liabilities. Notwithstanding subsection (a) and (b) above, after the Distribution Time: (i) the Generico
Parties shall be solely jointly and severally responsible for the continuation coverage requirements under COBRA and the portability requirements under the Health Insurance Portability and Accountability Act of 1996 (“HIPAA”) with
respect to the Former Alpha Employees and the Generico Personnel and their qualified beneficiaries under the applicable Generico Welfare Plans; provided, that (A) New Alpha LLC shall bear and be responsible for all costs, claims and other
Liabilities related to the satisfaction of such requirements to the extent the Generico Parties are not fully reimbursed therefor by insurance with third-party insurers (other than Liabilities related to such plans that result from matters of
non-compliance following the Distribution Time; provided that in no event shall the continued participation by Alpha Personnel in the Generico Welfare Plans constitute or be deemed to constitute a matter of non-compliance for these purposes) with
respect to the Former Alpha Employees in excess of required employee contributions and (B) New Alpha LLC may elect, upon reasonable notice to Generico, to assume responsibility for such requirements with respect to the Former Alpha Employees,
in which event Generico and the Generico Welfare Plans shall cease to have any responsibility under this Section 3.03(d), and (ii) the Alpha Parties shall be solely jointly and severally responsible for the continuation coverage
requirements under COBRA and the portability requirements under HIPAA with respect to the Alpha Employees and their qualified beneficiaries under the applicable New Alpha Welfare Plans. 
 ARTICLE IV 
 COMPENSATION MATTERS 
 AND NON-ERISA BENEFIT ARRANGEMENTS 
 4.01 Assumption of Non-ERISA Benefit Arrangements by the Generico Group; Cessation of Participation in Non-ERISA Benefit Arrangements. 
 (a) From and after the Distribution Time, the Generico Group shall assume and be solely responsible for the Non-ERISA Benefit Arrangements, including but not limited to the Alpha Option Plan and the American
Pharmaceutical Partners, Inc. 2001 Employee Stock Purchase Plan (the “ESPP”), including all Liabilities thereunder. 
  

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 (b) Each member of the Alpha Group shall cease to participate in all Non-ERISA Benefit Arrangements,
including but not limited to the Alpha Option Plan and the ESPP, at the Distribution Time. Participation in the Non-ERISA Benefit Arrangements, including but not limited to the Alpha Option Plan and the ESPP, will cease for all Alpha Personnel at
the Distribution Time. 
 4.02 Assumption of Employee Related Obligations. 
 (a) From and after the Distribution Time, the Generico Parties shall be solely responsible for all Liabilities (including administrative responsibilities)
related to the agreements and obligations described in Section 4.02(a)(i) through Section 4.02(a)(vi), and no Alpha Party or any of its Affiliates shall retain such Liabilities or have any responsibility with respect thereto:

 (i) Each Employee Agreement and Employment Agreement entered into prior to the Distribution Time between any member of the
Alpha Group and any of the Generico Personnel; provided, that nothing herein shall limit the rights of the Alpha Group or the Generico Group thereunder with respect to their business operations, to the extent provided therein. 
 (ii) Agreements entered into prior to the Distribution Time between any member of the Alpha Group and any Generico Independent Contractor.

 (iii) All wages, salary, ordinary compensation or commissions payable to any of the Generico Personnel after the
Distribution Time, and all vacation, paid time off, sick leave, or other fringe benefits accrued with respect to any of the Generico Personnel at the Distribution Time, whether earned before or after the Distribution Time. 
 (iv) All bonus and cash incentive compensation payment obligations, if any, payable after the Distribution Time to any of the Generico
Personnel, whether earned before or after the Distribution Time. 
 (v) All Liabilities with respect to any of the Generico
Personnel under the Non-ERISA Benefit Arrangements, whether earned or accrued before or after the Distribution Time (except to the extent that the Generico Group is fully reimbursed for such Liability by insurance with third-party insurers).

 (vi) All Liabilities of the Generico Business related to the Generico Personnel set forth on Schedules 3.01(e)(ii) and
3.01(e)(iii) of the Separation and Distribution Agreement. 
 The parties agree to negotiate in good faith with the Generico Personnel and any third parties,
if applicable, to cause the foregoing Liabilities to be assumed by the Generico Parties on terms no less favorable to the Generico Parties than those that apply to the Alpha Parties and to have the Alpha Group fully released from such Liabilities.
If any of the foregoing Liabilities cannot be assumed by the Generico Parties and the Alpha Group released therefrom for a reason beyond the control of the parties hereto, including the refusal of any such third party to consent to such an
assumption and release, then the Generico Parties shall reimburse the Alpha Group in the 

  

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event that any such Liabilities are paid by the Alpha Group, in accordance with Section 7.03, as though it had been assumed and paid by Generico.

 (b) From and after the Distribution Time, the Alpha Parties shall be solely responsible for all Liabilities related to the agreements and
obligations described in Section 4.02(b)(i) through Section 4.02(b)(iv), and no Generico Party or any of their respective Affiliates shall retain such Liabilities or have any responsibility with respect thereto: 

(i) All wages, salary, ordinary compensation or commissions payable to any of the Alpha Personnel after the Distribution Time, and all
vacation, paid time off, sick leave, or other fringe benefits accrued with respect any of the Alpha Personnel at the Distribution Time, whether earned before or after the Distribution Time. 
 (ii) All bonus and cash incentive compensation payment obligations, if any, payable after the Distribution Time to any of the Alpha
Personnel, whether earned before or after the Distribution Time. 
 (iii) All Liabilities with respect to any of the Alpha
Personnel under the Non-ERISA Benefit Arrangements, whether earned or accrued before or after the Distribution Time (except to the extent that the Alpha Group is fully reimbursed for such Liability by insurance with third-party insurers, and, with
respect to such Liabilities related to service or events prior to the Distribution Time, only to the extent accrued on the books of account of Alpha at the Distribution Time); provided that the Alpha Group shall not assume any Liabilities related to
such Non-ERISA Benefit Arrangements that result from matters of non-compliance prior to the Distribution Time. 
 (iv) All
Liabilities, regardless of when arising or incurred, under the ESPP or any other Benefit Plan, which Liabilities are not expressly assumed by the Generico Parties in this Agreement. 
 The parties agree to negotiate in good faith with the Alpha Personnel and any third parties, if applicable, to cause the foregoing Liabilities to be assumed by the Alpha Parties on terms no less favorable to the Alpha
Parties than those that apply to the Generico Parties and to have the Generico Group fully released from such Liabilities. If any of the foregoing Liabilities cannot be assumed by the Alpha Parties and the Generico Group released therefrom for a
reason beyond the control of the parties hereto, including the refusal of any such third party to consent to such an assumption and release, then the Alpha Parties shall reimburse the Generico Group for any such Liabilities paid by the Generico
Group, in accordance with Section 7.03, as though it had been assumed and paid by New Alpha LLC. 
 4.03 Bonus and Cash
Incentive Plans. 
 Without limiting the generality of Section 4.02, from and after the Distribution Time, the Generico Parties
shall be solely responsible for Alpha’s current bonus and cash incentive compensation plans and arrangements with respect to the Generico Employees and shall be solely responsible for all payment obligations earned by the Generico Employees
thereunder, subject to the Separation and Distribution Agreement. 
  

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 4.04 Equity Compensation Plans. 
 (a) Alpha Options Held by Generico Personnel and Gholdco Directors. Each Alpha Option held by any of the Generico Personnel or Gholdco Directors
that is outstanding immediately before the Distribution Time shall be converted at the Distribution Time into a Gholdco Option. Immediately following the Distribution Time, each Gholdco Option shall have the same terms and conditions as applied to
the corresponding Alpha Option to which it relates immediately prior to the Alpha Merger and shall continue to be subject to the terms and conditions provided in the applicable Alpha Option Plan and the applicable grant agreements (including,
without limitation, any rights of Gholdco with respect to such Gholdco Options contained therein). New Alpha, Gholdco and New Alpha LLC shall take such actions as may be necessary to effectuate the provisions of this Section 4.04(a). For the
avoidance of doubt, at no time will an Old Abraxis Option be deemed to relate to New Alpha LLC. The conversion referred to above shall be effected in accordance with the principles set forth in Exhibit A hereto, but notwithstanding the foregoing or
anything to the contrary herein or on Exhibit A, the modification of the Gholdco Options pursuant to this Section 4.04(a) shall be consistent with Section 424 of the Code and the regulations issued thereunder, if applicable, and
Section 409A of the Code and the regulations issued thereunder and shall comply with all Applicable Laws. 
 (b) Alpha Options Held
by Alpha Personnel and New Alpha Directors. Each Alpha Option held by any of the Alpha Personnel or New Alpha Directors that is outstanding immediately before the Distribution Time shall be converted at the Distribution Time into a New Alpha
Option. Immediately following the Distribution Time, each New Alpha Option shall have the same terms and conditions as applied to the corresponding Alpha Option to which it relates immediately prior to the Alpha Merger and shall continue to be
subject to the terms and conditions provided in the applicable Alpha Option Plan and the applicable grant agreements (including, without limitation, any rights of New Alpha with respect to such New Alpha Options contained therein). New Alpha,
Gholdco and New Alpha LLC shall each take such actions as may be necessary to effectuate the provisions of this Section 4.04(b). For the avoidance of doubt, at no time will an Old Abraxis Option be deemed to pertain to New Alpha LLC. The
conversion referred to above shall be effected in accordance with the principles set forth on Exhibit A hereto, and notwithstanding the foregoing or anything to the contrary herein or on Exhibit A, shall be consistent with Section 424 of the
Code and the regulations issued thereunder, if applicable, and Section 409A of the Code and the regulations issued thereunder and shall comply with all Applicable Laws. 
 (c) Restricted Stock Units. 
 (i) Each Alpha Restricted Stock Unit subject to the American Pharmaceutical Partners, Inc. 2001 Stock Incentive Plan (the “2001 Plan”) held by Generico Employees that is outstanding immediately before the Distribution Time
shall be converted at the Distribution Time into a Gholdco Restricted Stock Unit. Immediately following the Distribution Time, each Gholdco Restricted Stock Unit shall have the same terms and conditions as applied to the corresponding Alpha
Restricted Stock Unit to which it relates immediately prior to the Alpha Merger and shall continue to be subject to the terms and conditions provided in the 2001 Plan and the applicable grant agreements (including, 

  

 12 

 
without limitation, any rights of Gholdco with respect to such Gholdco Restricted Stock Units contained therein). New Alpha, Gholdco and New Alpha LLC shall
take such actions as may be necessary to effectuate the provisions of this Section 4.04(c)(i). For the avoidance of doubt, at no time will an Alpha Restricted Stock Unit be deemed to pertain to New Alpha LLC. The conversion referred to above
shall be effected in accordance with the principles set forth on Exhibit A hereto, and notwithstanding the foregoing or anything to the contrary herein or on Exhibit A shall be consistent with Section 409A of the Code and the regulations issued
thereunder and shall comply with all Applicable Laws. 
 (ii) Each Alpha Restricted Stock Unit subject to the 2001 Plan held
by Alpha Employees that is outstanding immediately before the Distribution Time shall be converted at the Distribution Time into a New Alpha Restricted Stock Unit. Immediately following the Distribution Time, each New Alpha Restricted Stock Unit
shall have the same terms and conditions as applied to the corresponding Alpha Restricted Stock Unit to which it relates immediately prior to the Alpha Merger and shall continue to be subject to the terms and conditions provided in the 2001 Plan and
the applicable grant agreements (including, without limitation, any rights of New Alpha with respect to such New Alpha Restricted Stock Units contained therein). New Alpha, Gholdco and New Alpha LLC shall each take such actions as may be necessary
to effectuate the provisions of this Section 4.04(c)(ii). For the avoidance of doubt, at no time will any Alpha Restricted Stock Unit be deemed to relate to New Alpha LLC. The conversion referred to above shall be effected in accordance with
the principles set forth on Exhibit A hereto and notwithstanding the foregoing or anything to the contrary herein or on Exhibit A, shall be consistent with Section 409A of the Code and the regulations issued thereunder and shall comply with all
Applicable Laws. 
 (iii) Each Alpha Restricted Stock Unit subject to the American BioScience, Inc. Restricted Stock Unit Plan
I (“Plan I”) or the American BioScience, Inc. Restricted Stock Unit Plan II (“Plan II”) held by a Generico Employee that is outstanding immediately before the Distribution Time shall be converted at the Distribution
Time into a Gholdco Restricted Stock Unit. Immediately following the Distribution Time, each Gholdco Restricted Stock Unit shall have the same terms and conditions as applied to the corresponding Alpha Restricted Stock Unit to which it relates
immediately prior to the Alpha Merger and shall continue to be subject to the terms and conditions provided in Plan I or Plan II, as applicable, and the applicable grant agreements (including, without limitation, any rights of Gholdco with respect
to such Gholdco Restricted Stock Unit contained therein). Gholdco, New Alpha and New Alpha LLC shall take such actions as may be necessary to effectuate the provisions of this Section 4.04(c)(iii). For the avoidance of doubt, at no time will an
Alpha Restricted Stock Unit be deemed to pertain to New Alpha LLC. The conversion referred to above shall be effected in accordance with the principles set forth on Exhibit A hereto, but notwithstanding the foregoing or anything to the contrary
herein or on Exhibit A, shall be consistent with Section 409A of the Code and the regulations issued thereunder and shall comply with all Applicable Laws. 
  

 13 

 (iv) Each Alpha Restricted Stock Unit subject to Plan I or Plan II held by an Alpha
Employee that is outstanding immediately before the Distribution Time shall be converted at the Distribution Time into a New Alpha Restricted Stock Unit. Immediately following the Distribution Time, each New Alpha Restricted Stock Unit shall have
the same terms and conditions as applied to the corresponding Alpha Restricted Stock Unit to which it relates immediately prior to the Alpha Merger and shall continue to be subject to the terms and conditions provided Plan I or Plan II, as
applicable, and the applicable grant agreements (including, without limitation, any rights of New Alpha with respect to such New Alpha Restricted Stock Unit contained therein). New Alpha, New Alpha LLC and Gholdco shall each take such actions as may
be necessary to effectuate the provisions of this Section 4.04(c)(iv). For the avoidance of doubt, at no time will an Alpha Restricted Stock Unit be deemed to pertain to New Alpha LLC. The conversion referred to above shall be effected in
accordance with the principles set forth on Exhibit A hereto, but notwithstanding the foregoing or anything to the contrary herein or on Exhibit A, shall be consistent with Section 409A of the Code and the regulations issued thereunder and
shall comply with all Applicable Laws. 
 (d) Registration Statements. Each of Gholdco and New Alpha shall, by the first business day
following the day on which the Distribution Time occurs, file with the Securities and Exchange Commission a registration statement on Form S-8 (or successor form), or an amendment to an existing Form S-8, with respect to the Gholdco Common Stock and
New Alpha Common Stock to be issued upon exercise or settlement (as applicable) of the Gholdco Options, Gholdco Restricted Stock Units, New Alpha Options and New Alpha Restricted Stock Units and shall use its reasonable best efforts to maintain the
effectiveness of such registration statement (and to maintain the current status of the prospectus or prospectuses contained therein and to comply with an applicable state securities or “blue sky” laws) for so long as such awards remain
outstanding. 
 ARTICLE V 
 QUALIFIED RETIREMENT PLANS 
 5.01 Defined Contribution Plans. 
 (a) Effective as of the Distribution Time, the Generico Group shall assume all Liabilities (including administrative responsibilities) under the Abraxis
BioScience, Inc. Savings and Retirement Plan. For purposes of this Agreement, following such assumption, such plan shall be referred to as the “Generico Profit Sharing Plan.” 
 (b) Establishment of New Alpha Defined Contribution Plan. 
 (i) Establishment of New Alpha Profit Sharing Plan. As soon as administratively practicable after the Distribution Time but in any
event prior to the end of the term of the Transition Services Agreement, New Alpha shall (or shall cause another member of the Alpha Group to) adopt, and the active Alpha Employees shall be eligible to participate in, a defined contribution plan
intended to be qualified under Section 401(a) of the Code and trust intended to be qualified under Section 501(a) of the 

  

 14 

 
Code (the “New Alpha Profit Sharing Plan”). Subject to the asset transfers described in Section 5.01(b)(ii), the Alpha Parties shall
assume and thereafter be jointly and severally responsible for all then existing or future Liabilities on behalf of Alpha Personnel related to the New Alpha Profit Sharing Plan and the administration thereof and the Generico Parties shall not retain
any such Liabilities. As soon as practicable after the adoption of the New Alpha Profit Sharing Plan, Alpha shall, to the extent applicable, submit an application to the IRS for a determination regarding the qualification of the New Alpha Profit
Sharing Plan and shall take any actions not inconsistent with the other general commitments of the Alpha Parties contained in this Agreement and make any amendments necessary to receive a favorable determination letter. 
 (ii) Transfer of Account Balances. As soon as administratively practicable after the receipt of the determination letter referred
to in Section 5.02(b)(i) (a copy of which shall be provided to Generico), the Alpha Parties and the Generico Parties shall cooperate to cause the Generico Profit Sharing Plan to transfer to the New Alpha Profit Sharing Plan assets having a
value as of the applicable valuation date that are equal to the value of the account balances of, and Liabilities with respect to, all Alpha Personnel with account balances, whether or not vested, under the Generico Profit Sharing Plan as of such
valuation date. Such transferred assets shall be as mutually agreed between New Alpha and Gholdco (provided, that (i) the parties shall endeavor to “map” the investments elected by the Alpha Personnel participating in the Generico
Profit Sharing Plan to similar investments in the New Alpha Profit Sharing Plan, (ii) promissory notes for outstanding participant loans shall be transferred and (iii) if the New Alpha Profit Sharing Plan permits New Alpha Common Stock as
an investment alternative, then any New Alpha Common Stock held in the accounts of the Alpha Personnel shall be transferred), and such asset transfer shall be in accordance with Section 414(l) of the Code. Liabilities with respect to the
administration of any qualified domestic relations orders (as defined in Section 414(p) of the Code) received with respect to any assets transferred to the New Alpha Profit Sharing Plan shall be transferred to the Alpha Parties at the time such
assets are transferred. 
 (iii) Past Service Credit and Vesting. With respect to all Alpha Employees and without
duplication of benefits, the New Alpha Profit Sharing Plan shall (i) recognize, to the extent applicable, all service, compensation and other determinations that, at the Distribution Time, were recognized under the Generico Profit Sharing Plan
for purposes of determining eligibility, participation, vesting, and determinations of the levels of benefits for Alpha Employees (provided, that service by the Alpha Personnel with the Alpha Group following the Distribution Time shall also be
recognized by the New Alpha Profit Sharing Plan), and (ii) maintain the vesting schedule applicable under the Generico Profit Sharing Plan for accounts transferred from the Generico Profit Sharing Plan. 
 (iv) Elections and Designations. To the extent applicable, all participant elections and beneficiary designations made by the Alpha
Personnel under the Generico Profit Sharing Plan shall be transferred to, and be in full force and effect under, the New 

  

 15 

 
Alpha Profit Sharing Plan until such participant elections and beneficiary designations are replaced or revoked by the Alpha Personnel who made the election
or designation. 
 (v) Cessation of Participation in the Generico Profit Sharing Plan. Each member of the Alpha Group
shall cease to be a participating employer in the Generico Profit Sharing Plan at the Distribution Time, and, except as provided in the Transition Services Agreement, participation in the Generico Profit Sharing Plan will cease for all Alpha
Personnel no later than the end of the term of the Transition Services Agreement. 
 5.02 Further Cooperation. The Alpha
Parties and the Generico Parties will cooperate in good faith in the filing of documents required by this Agreement to generally effect the purposes of this Agreement and to resolve any discrepancies or obtain any missing data for purposes of
determining benefit eligibility, participation, vesting and calculation of benefits with respect to any of the Generico Employees. 
 ARTICLE VI 
 FOREIGN PLANS 
 The terms and conditions set forth in this Agreement shall be applied equally, to the maximum extent practicable, but subject to all Applicable Laws, to each Non-U.S. Benefit Plan. In the event that the terms and
conditions of this Agreement cannot be applied equally to any Non-U.S. Benefit Plan, the parties shall cooperate in good faith to give effect to the terms of this Agreement, to the maximum extent practicable. 
 ARTICLE VII 
 GENERAL PROVISIONS 

 7.01 Preservation of Rights of Plan Sponsors; No Third Party Beneficiaries or Rights. The parties hereto acknowledge and
agree that the provisions of this Agreement represent the obligations between the parties to this Agreement only and shall not be construed to (i) establish, amend or modify any benefit plan, program, agreement or arrangement maintained by any
of them; (ii) alter or limit the ability of the parties, as sponsors or adopting employers of any employee benefit plan, to amend, modify or terminate any benefit plan, program, agreement or arrangement at any time assumed, established,
sponsored or maintained by any of them; (iii) confer upon any person any right to employment or continued employment for any period of time by reason of this Agreement, or any right to a particular term or condition of employment; or
(iv) confer upon any person any other rights as a third-party beneficiary of this Agreement. 
 7.02 Administrative
Complaints/Litigation. 
 (a) After the Distribution Time, the Generico Parties shall assume, and be jointly and severally liable for,
the handling, administration, investigation, defense and settlement or other resolution of actions, including, without limitation, regarding ERISA, occupational safety and health, employment standards, wage and hour claims, withholding matters,
union grievances, wrongful dismissal, discrimination or human rights and unemployment compensation claims, asserted at any time against the Alpha Group or the Generico Group by any of the Generico Personnel or any other person (including any
Governmental Entity) arising out of or relating to 

  

 16 

 
employment of any Generico Personnel (or any person who after the Distribution Time becomes an employee of a member of the Generico Group, solely with
respect to his or her employment after the Distribution Time) with the Generico Business or Generico or the compensation and/or employee benefits of the Generico Personnel. Any Liabilities arising from such actions shall be deemed Generico
Liabilities under the Separation and Distribution Agreement; provided that, notwithstanding anything herein to the contrary, nothing in this Agreement will be deemed to cause the Generico Parties to assume or become responsible for any Excluded
Liabilities (as defined in the Separation and Distribution Agreement) described in Section 3.01(f)(i), (v) or (vii) of the Separation and Distribution Agreement. 
 (b) The Alpha Parties shall retain, or after the Distribution Time shall assume, as applicable, and be jointly and severally liable for, the handling,
administration, investigation, and defense and settlement or other resolution of actions, including, without limitation, regarding ERISA, occupational safety and health, employment standards, wage and hour claims, withholding matters, union
grievances, wrongful dismissal, discrimination or human rights and unemployment compensation claims, asserted at any time against the Generico Group or the Alpha Group by any of the Alpha Personnel or any other person (including any Governmental
Entity) arising out of or relating to employment of any Alpha Personnel (or any person who after the Distribution Time becomes an employee of a member of the Alpha Group, solely with respect to his or her employment after the Distribution Time) with
the Alpha Business or Alpha or the compensation and/or employee benefits of the Alpha Personnel. Any Liabilities arising from such actions shall be deemed Alpha Liabilities under the Separation and Distribution Agreement. 
 7.03 Reimbursement and Indemnification. The parties hereto agree to reimburse one another, within 30 days of receipt from another party of
appropriate verification, for all Indemnifiable Losses that each may incur on behalf of the other as a result of any of the Benefit Plans or any of the termination or severance obligations set forth in Section 2.02. All Liabilities
retained, assumed or indemnified against by the Generico Parties pursuant to this Agreement shall be deemed Generico Liabilities, and all Liabilities retained, assumed or indemnified against by the Alpha Parties pursuant to this Agreement shall be
deemed Alpha Liabilities, and in each case shall be subject to the indemnification provisions of Article IV of the Separation and Distribution Agreement. 
 7.04 Payment of and Accounting Treatment for Expenses. Except as specifically provided in the Separation and Distribution Agreement or as the Generico Parties and the Alpha Parties otherwise mutually
agree, all expenses (and the accounting treatment related thereto) through the Distribution Time regarding matters addressed herein shall be handled and administered in accordance with Alpha’s historical accounting and financial practices and
procedures pertaining to such matters. 
 7.05 Sharing of Participant Information. New Alpha and Generico shall share, New
Alpha shall cause each applicable member of the Alpha Group to share, and Generico shall cause each applicable member of the Generico Group to share, with each other and their respective agents and vendors (to the extent permitted by Applicable Law)
all participant information necessary for the efficient and accurate administration of each of the Benefit Plans sponsored or 

  

 17 

 
maintained by any member of the Alpha Group and the Benefit Plans sponsored or maintained by any member of the Generico Group following the Distribution
Time. New Alpha and Generico and their respective authorized agents shall, subject to Applicable Laws and understandings regarding confidentiality, be given reasonable and timely access to, and may make copies of, all information relating to the
subjects of this Agreement in the custody of the other party, to the extent necessary for such administration, in each case without application of any limitation or restriction set forth in Article VI of the Separation and Distribution Agreement.
Generico and New Alpha shall also cooperate to share all such information regarding any issue relating to the compensation of the Generico Personnel as may be required in order to satisfy any requirements related to federal, state and/or local
income tax reporting (including, for purposes of preparing a Form W-2 for each such employee) and withholding, all in accordance with the terms of the Tax Allocation Agreement. 
 7.06 Relationship of Parties. Nothing in this Agreement shall be deemed or construed by the parties or any third party as creating the
relationship of principal and agent, partnership or joint venture between the parties, it being understood and agreed that no provision contained herein, and no act of the parties, shall be deemed to create any relationship between the parties other
than the relationship set forth herein. 
 7.07 Cooperation. The Alpha Parties and the Generico Parties shall each cooperate in
good faith, including by making personnel available to one another at mutually agreed times, as necessary or appropriate to carry out the purposes of this Agreement. 
 7.08 No Duplication of Benefits. It is the intention of the parties that nothing in this Agreement shall allow for any of the Generico Personnel or Alpha Personnel to receive duplicative benefits.
Accordingly, notwithstanding any other provision of this Agreement, New Alpha LLC and Generico shall agree on methods and procedures to prevent the Generico Personnel and the Alpha Personnel from receiving duplicative benefits. 
 ARTICLE VIII 
 MISCELLANEOUS 

 8.01 Entire Agreement. This Agreement, the Separation and Distribution Agreement and other Transaction Agreements (as
defined in the Separation and Distribution Agreement), including any annexes, schedules and exhibits hereto or thereto, and other agreements and documents referred to herein and therein, will together constitute the entire agreement between the
parties with respect to the subject matter hereof and thereof and will supersede all prior negotiations, agreements and understandings of the parties of any nature, whether oral or written, with respect to such subject matter. 
 8.02 Survival of Agreements. Except as specifically contemplated by this Agreement, all covenants and agreements of the parties contained
in this Agreement will remain in full force and effect and survive the Distribution Time. 
  

 18 

 8.03 Governing Law. This Agreement will be governed by and construed in accordance with the
laws of the State of Delaware (without giving effect to choice of law principles thereof). 
 8.04 Notices. Notices to the
parties hereunder shall be provided in accordance with Section 8.04 of the Separation and Distribution Agreement. 
 8.05
Incorporation by Reference. Sections 8.06 through 8.20 of the Separation and Distribution Agreement are hereby incorporated by reference into this Agreement and shall apply to this Agreement as if set forth herein in full. 
  

 19 

 IN WITNESS WHEREOF, the parties have caused this agreement to be executed in their names by a duly
authorized officer as of the date first written above. 
  

	
	APP PHARMACEUTICALS, INC.
	
	  

	Name:
	Title:
	
	APP PHARMACEUTICALS, LLC
	
	  

	Name:
	Title:
	
	ABRAXIS BIOSCIENCE, LLC
	
	  

	Name:
	Title:
	
	NEW ABRAXIS, INC.
	
	  

	Name:
	Title:Form of Manufacturing Agreement

 Exhibit 10.5 
 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for confidential treatment that has been filed with the Securities and Exchange Commission. 
 FORM 
 OF 
 MANUFACTURING AGREEMENT 
 BETWEEN

 NEW ABRAXIS, INC. 
 (TO BE
RENAMED ABRAXIS BIOSCIENCE, INC.) 
 AND 
 APP PHARMACEUTICALS LLC 
  

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 MANUFACTURING AGREEMENT 
 THIS MANUFACTURING AGREEMENT (this “Agreement”) is made by and between New Abraxis, Inc., to be renamed Abraxis BioScience, Inc., a
Delaware corporation (“NEW ALPHA”), and APP Pharmaceuticals LLC, a Delaware limited liability company (“GENERICO”), as of this      day of
                    , 2007 (the “Effective Date”). 
 RECITALS 
 A. NEW ALPHA or one or more its subsidiaries has developed and owns the rights to the
Product and the Pipeline Products (both as defined below). 
 B. GENERICO has the capabilities, facilities and equipment designed for and capable of
performing the Generico Manufacturing (as defined below) with respect to the Product and the Pipeline Products, and GENERICO desires to perform such Generico Manufacturing upon the terms and conditions contained herein. 
 AGREEMENT 
 NOW, THEREFORE, in
consideration of the above Recitals, the mutual covenants and agreements contained herein, and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Parties hereto hereby agree as follows:

 1. Definitions. For purposes of this Agreement, in addition to other defined terms set forth in this Agreement, the terms set forth
below will have the following meanings: 
 1.1 “Action” means any actual or threatened claim, suit, demand, arbitration,
hearing, inquiry, proceeding, complaint, charge or investigation by or before any court, Regulatory Authority or arbitrator. 
 1.2
“Affiliate” means, with respect to any Person, any entity controlling, controlled by or under the common control of such Person. Such entity will be considered an Affiliate only for the time during which such control exists. For the
purpose of this Agreement, “control” (together with its correlative meanings “controlled by” or “under common control with”) means having, directly or indirectly, the power to direct or cause the direction of management
and policies of such entity. For purposes of this Agreement, none of Gholdco or any of its subsidiaries, including GENERICO, shall be considered an affiliate of NEW ALPHA or any of its subsidiaries, and none of NEW ALPHA or any of its subsidiaries
shall be considered an affiliate of Gholdco or any of its subsidiaries, including GENERICO. 
 1.3 “Alternative Compensation
Amount” has the meaning set forth in Section 2.8(B). 
 1.4 “Annual Forecasts” means, for 2008, the annual
forecasts of the aggregate units of Product and Pipeline Products to be supplied by GENERICO from each Facility that are attached as Part A of Schedule 1.4 hereto, and for subsequent years, the annual forecasts of the aggregate units of
Product and Pipeline Products from each Facility provided by NEW ALPHA to 

  

 1 

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 
GENERICO at least thirty (30) days prior to January 1 of that year; provided, however, that the forecasts provided by NEW ALPHA with
respect to each year subsequent to 2008 shall not, without the approval of GENERICO (which approval shall not be unreasonably be withheld or delayed), provide for the supply of Product and Pipeline Products from any Facility that is more than (***)
of the aggregate units to be supplied from that Facility reflected in the estimates for 2009, 2010, 2011 and 2012 as set forth in Part B of Schedule 1.4. The 2009, 2010, 2011 and 2012 estimates shall not become “Annual Forecasts”
for purposes hereof until provided by NEW ALPHA under the terms of this Agreement. 
 1.5 “Breach” has the meaning set forth
in Section 10.2. 
 1.6 “cGMP(s)” means current good manufacturing practices established under the FDCA and the
regulations promulgated thereunder; and other comparable laws and regulations of any competent Regulatory Authorities applicable to manufacturing activities or the Facility for the Product and Pipeline Products, all as amended from time to time.

 1.7 “Chemical Ingredients” means, with respect to the Product or any Pipeline Product, the active pharmaceutical
ingredient(s) and human albumin in the Product or Pipeline Product, as applicable. 
 1.8 “Chemical Solution” means end
product obtained after New Alpha Manufacturing (other than the New Alpha Review and Release) is complete with respect to the Product or any Pipeline Product. 
 1.9 “Chemical Testing” means in-process testing of the chemical properties of the Product or any Pipeline Product during the process of manufacturing Product or any Pipeline Product. 
 1.10 “Claim Notice” has the meaning set forth in Section 12.3. 
 1.11 “Competitor” means (***). 
 1.12 “Components” means all containers, closures, packaging components, labels and labeling necessary for the manufacture of the Product or any Pipeline Product as finished goods. 
 1.13 “Damages” means any and all losses, liabilities, obligations, costs, expenses, damages or judgments of any kind or nature
whatsoever (including reasonable attorneys’, accountants’ and experts’ fees, disbursements of counsel and other costs and expenses). 
 1.14 “EMEA” means the European Medicines Evaluation Agency or any successor agency. 
 1.15 “Effective
Date” means the date written in the preamble of this Agreement, as set forth above. 
 1.16 “Estimated Generico
Manufacturing Plan” means NEW ALPHA’s estimate of the units of the Product with respect to which NEW ALPHA will place Purchase Orders during each month of each rolling 12-month period during the Term, which estimate will be delivered
by 

  

 2 

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 
NEW ALPHA to GENERICO on a monthly basis; provided, however, that in no event will a given monthly estimate vary by more than (***) from the
monthly estimate issued in respect of the immediately preceding month. The Estimated Generico Manufacturing Plan shall include, with respect to the Product, NEW ALPHA’s estimated requirements for commercial sale, clinical supply, validation,
stability or other uses thereof, and for Generico Manufacturing at each Facility, during each month of the applicable rolling 12-month basis. 
 1.17 “Facility” means (i) the Melrose Park Facility and (ii) the Grand Island Facility. 
 1.18
“FDA” means the United States Food and Drug Administration or any other successor agency of the United States Federal Government. 
 1.19 “FDA Modernization Plan” has the meaning set forth in Section 14.1(A). 
 1.20 “FDCA”
means the Federal Food, Drug, and Cosmetic Act (21 U.S.C. Section 301 et. seq.), as amended from time to time. 
 1.21 “Force
Majeure” has the meaning set forth in Section 15.4(A). 
 1.22 “GENERICO Indemnified Parties” has the meaning
set forth in Section 12.2. 
 1.23 “Generico Manufacture,” “Generico Manufactured” and
“Generico Manufacturing” means the acquisition, sampling, testing and release of Components, the acquisition and sampling of Materials and testing of Materials supplied by GENERICO such as water for injection (“WFI”) and
nitrogen, the sampling of Chemical Ingredients and the manufacturing, lyophilization, packaging, labeling, filling, holding, Microbiologic Testing of the Product and Pipeline Products as more fully set forth on Exhibit A. For the avoidance of
doubt, Generico Manufacturing does not include New Alpha Manufacturing. 
 1.24 “Generico Products” means all of the
existing products being manufactured by GENERICO from time to time, including any variations of such products in formulation, dosage, delivery system, or the like (but, for the avoidance of doubt, in no event will the Generico Products include any
product incorporating “nab” technology). 
 1.25 “Gholdco” means Abraxis BioScience, Inc. (formerly known as
Generico Holdings, Inc. and to be renamed APP Pharmaceuticals, Inc.), a Delaware corporation and the parent company of GENERICO. 
 1.26
“Grand Island Facility” means GENERICO’s manufacturing facility(s) whether owned or leased located at 3159 Staley Road, Grand Island, New York. 
 1.27 “Grand Island Lease” has the meaning set forth in Section 10.1. 
 1.28
“HPFB” means the Health Products and Food Branch of Health Canada or any successor agency of the Canadian government. 
 1.29 “IHI” means the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use or any successor thereto. 
  

 3 

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 1.30 “Indemnifiable Claim” has the meaning set forth in Section 12.3.

 1.31 “Indemnified Party” has the meaning set forth in Section 12.3. 
 1.32 “Indemnifying Party” has the meaning set forth in Section 12.3. 
 1.33 “Legal Requirement” means any federal, state or local law, ordinance, regulation, permit, order, writ, judgment, injunction, decree
or award, or any rule, regulation or published guidelines or any statement having the effect of law, promulgated by any Regulatory Authority, including cGMPs. 
 1.34 “Management Fee” has the meaning set forth in Section 13. 
 1.35
“Materials” means, with respect to the Product or any Pipeline Product, all inactive raw materials and excipients, excluding human albumin, used in the formulation of the Product or any Pipeline Product necessary for their
manufacture as finished goods. 
 1.36 “Melrose Park EU Plan” has the meaning set forth in Section 14.2(A). 

1.37 “Melrose Park Facility” means GENERICO’s manufacturing facility(s) whether owned or leased located at 2020 Ruby Street,
Melrose Park, Illinois. 
 1.38 “Melrose Park Lease” has the meaning set forth in Section 10.1. 
 1.39 “MHLW” means Japan’s ministry of Health, Labor and Welfare (also known as “Korosho”) or any successor agency of the
government of Japan. 
 1.40 “MOHFW” means India’s ministry of Health & Family Welfare or any successor
agency. 
 1.41 “Microbiologic Testing” means the microbiologic testing of the Product or any Pipeline Product, as
applicable, at the beginning of Generico Manufacturing and at the completion of Generico Manufacturing. 
 1.42 “New Alpha
Manufacture,” “New Alpha Manufactured” and “New Alpha Manufacturing” means the acquisition, testing and release of Chemical Ingredients, the testing and release of Materials (other than Materials supplied
by GENERICO such as WFI and nitrogen) and subsequent formulating, compounding and Chemical Testing of the Product or any Pipeline Products as more fully set forth on Exhibit A, and the New Alpha Review and Release. 
 1.43 “New Alpha Review and Release” means the supervision and signoff contemplated by Section 2.9 of this Agreement and the written
release of the Product or any Pipeline Product, as applicable, following the completion of the Generico Manufacturing with respect thereto. 
 1.44 “Parties” means GENERICO and NEW ALPHA (“Party” meaning one of the Parties). 
  

 4 

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 1.45 “Person” means any natural person, corporation, partnership, limited
partnership, limited liability company, proprietorship, other business organization, trust, union, association or Regulatory Authority. 
 1.46 “Pipeline Products” means (A) ABI-008, ABI-009, ABI-010 and ABI-011 and (B) other products as identified by NEW ALPHA that GENERICO is reasonably capable of performing Generico Manufacturing at one or both of
the Facilities, and (***) and G-CSF (granulocyte-colony stimulating factor). Each of the Pipeline Products in clauses (A) and (B) shall either (x) involve substantially the same Generico Manufacturing steps, time and resources as the
Product or (y) shall (i) not require any material addition, upgrade or modification to any GENERICO Facility (except where such addition, upgrade or modification would not otherwise have one of the effects described in clauses
(ii) and (iii) below, and NEW ALPHA agrees to reimburse GENERICO in accordance with the last sentence of this Section 1.46 in respect thereof), (ii) not require any reallocation or diversion in any material respect of employees,
space or other resources of GENERICO and (iii) not otherwise impair or disrupt in any material respect the ability of GENERICO to conduct its business or perform its obligations under this Agreement. NEW ALPHA shall reimburse GENERICO for all
incremental costs reasonably incurred by GENERICO and paid to third parties (with the approval of NEW ALPHA not to be unreasonably withheld) as a result of GENERICO manufacturing any Pipeline Products described in clauses (A) and (B).

 1.47 “Product” means ABRAXANE®, a cremapahor-free pacilitaxel formulation, and any modifications thereto made by NEW ALPHA, subject to Section 2.2(G), and provided that, as modified, the product remains an injectible formulation of
paclitaxel. 
 1.48 “Product Liability Costs” has the meaning set forth in Section 9.6. 
 1.49 “Product Liability Claim” means any Action by a third party and any appeal from any Action asserted by a third party with respect
to the Product or any Pipeline Product alleging product liability, product defect, design, manufacturing, packaging or labeling defect, failure to warn, or any similar action relating to the formulation, manufacture, use or safety of the Product or
any Pipeline Product, as applicable. 
 1.50 “Projected Cycle Time” means, for any year, (i) with respect to NEW ALPHA,
the projected lyophilizer cycle time required by NEW ALPHA for that year based on the most recent Annual Forecast determined without giving effect to the permitted (***) increase in the definition of Annual Forecast or the (***) increase permitted
in Section 2.6 (i.e., not more than estimated in Schedule 1.4), and (ii) with respect to GENERICO, the projected lyophilizer cycle time required by GENERICO for that year based on the production forecasts for that year
attached as part of Schedule 1.4 hereof. 
 1.51 “Proprietary Information” means all information relating to the
Product or any Pipeline Product, as applicable, concerning the properties, composition or structure of the Product or any Pipeline Product, as applicable, the New Alpha Manufacturing of the Product or any Pipeline Product, as applicable, or the
machines used to New Alpha Manufacture the Product or any Pipeline Product, as applicable, the development, marketing or other commercialization of the Product or any Pipeline Product, as applicable, (including, without limitation, reagents, 

  

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confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 
computer programs, algorithms, analytical methodology, suppliers of ingredients and equipment, names and expertise of employees and consultants, know-how,
formulas, processes, ideas, inventions, whether patentable or not, schematics and other technical, business, financial, customer and product development plans, forecasts, strategies and information relating to the Product and the Pipeline Products),
whether previously, currently or subsequently disclosed to the other Party. Technology, innovations, improvements and modifications relating to the Product or any Pipeline Product or made by or for NEW ALPHA or any of its subsidiaries will be
considered Proprietary Information of NEW ALPHA. 
 1.52 “Proprietary Rights” means any and all patent rights, copyrights,
mask work, trade secret rights and all other intellectual and industrial property rights. 
 1.53 “Proration Percentage”
means, for any year, with respect to a Party, a fraction expressed as a percentage, the numerator of which is such Party’s Projected Cycle Time for such year and the denominator of which is the aggregate Projected Cycle Time of both Parties for
such year. 
 1.54 “Proration Period” has the meaning set forth in Section 2.7(A). 
 1.55 “Purchase Order” means written orders for a quantity of the Product or a number of batches of any Pipeline Product issued by NEW
ALPHA and placed with GENERICO. Each Purchase Order shall separately identify whether the Product or Pipeline Products subject to such Purchase Order are for commercial sale, clinical supply, validation, stability or other uses, and shall indicate
the Facility at which the Generico Manufacturing shall occur, if applicable, and the Territory in which such quantities will be sold or used for clinical testing; provided, however, that such Purchase Order shall be in accordance with
the applicable Estimated Generico Manufacturing Plan as set forth in Section 2.6. 
 1.56 “Reasonable Efforts” means a
reasonable sustained, continued and active application of diligent efforts, resources and urgency consistent with the manner in which such efforts were provided by New Abraxis, LLC (and its predecessor Abraxis BioScience, Inc.) and their
subsidiaries prior to the Effective Date (but not including any historical preference or priority given to the Product as compared with GENERICO’s pharmaceutical products), and no less than the efforts, urgency and resources commonly used by
GENERICO in manufacturing for its own business. 
 1.57 “Recall” has the meaning set forth in Section 8.1. 

1.58 “Regulatory Approval” means (i) with respect to GENERICO, any and all actions required by a Regulatory Authority for the
manufacture of the Product in the Territory, and (ii) with respect to NEW ALPHA, the filing and procurement of any registration, permit and approval required by applicable Regulatory Authorities for the importation, marketing, sale,
distribution and use of the Product in the Territory. 
 1.59 “Regulatory Authority” means (i) the FDA, (ii) with
respect to the Grand Island Facility, the FDA and the EMEA, and (iii) subject to Section 2.2(C), the TGA, the MHLW, the MOHFW, the IHI and any other national, multinational, federal, state, provincial or local 

  

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regulatory agency, department, bureau or other governmental entity in the Territory that has regulatory authority over the Product or any Pipeline Product.

 1.60 “Rejected Product” means batches of Product or Pipeline Product which are either (i) lost in production (or are
not in compliance with the applicable Specifications, cGMPs, the FDCA and any other applicable Legal Requirements) as a result of the Generico Manufacturing or New Alpha Manufacturing or a failure or deficiency of the Generico Manufacturing or New
Alpha Manufacturing, or (ii) determined by final decision of NEW ALPHA’s or GENERICO’s quality group not to be suitable for final release. 
 1.61 “Specifications” means the description and attributes, Chemical Ingredients, Components and Materials for the Product or any Pipeline Product, along with manufacturing procedures for such
Product. Specifications exclude NEW ALPHA Proprietary Information. The Specifications include without limitation: 
  

	 	(A)	sampling requirements (including lab and microbiological); 

  

	 	(B)	intermediate specifications; 

  

	 	(C)	processing aids; 

  

	 	(D)	finished Product release criteria; 

  

	 	(E)	stability specifications; 

  

	 	(F)	Microbiologic Testing methods; and 

  

	 	(G)	packaging, labels and labeling. 

 1.62 “Supply
Deficit Period” has the meaning set forth in Section 2.8(A). 
 1.63 “Technology” means any and all ideas,
techniques, inventions, methods, data, information, formulae, processes, trade secrets, analytical methodology, intellectual property, know-how, and test results, whether patentable or not, and whether or not reduced to practice, including
Proprietary Rights, owned, controlled or otherwise in possession of or used by NEW ALPHA as of the Effective Date, or during the Term and necessary or useful to make, have made, develop, have developed, use, import, market, offer for sale or sell
the Product or any Pipeline Product. 
 1.64 “Term” has the meaning set forth in Section 10.1. 
 1.65 “TGA” means the Therapeutic Goods Administration, Department of Health and Ageing, Australia. 
 1.66 “Territory” means (***). 
  

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 1.67 “Warehouse Services Agreement” means the Warehouse Services Agreement, dated as
of the Effective Date, between New Abraxis, LLC and Generico, as it may be amended from time to time. 
 2. Generico Manufacturing and Other Services.

 2.1 Subject to the terms, conditions and provisions of this Agreement, GENERICO hereby covenants and agrees that during the Term it will
perform the Generico Manufacturing with respect to the Product and the Pipeline Products as requested by NEW ALPHA in accordance with the terms hereof. GENERICO will perform the Generico Manufacturing with respect to the Product and the Pipeline
Products solely and exclusively for NEW ALPHA and its designees. 
 2.2 GENERICO will, in good faith, use Reasonable Efforts to: 

(A) obtain and maintain such approvals and licenses as may be required by any Regulatory Authority or Legal Requirement for the manufacturing at the
Facilities of the Product or any Pipeline Product for commercial sale or clinical development in the United States and its territories and possessions; without limiting the foregoing, GENERICO shall use Reasonable Efforts to obtain as promptly as
practicable such approvals and licenses as may be required by any Regulatory Authority or Legal Requirement for the manufacturing of the Product for commercial sale in the United States on Line 6 of the Grand Island Facility; provided,
however, that nothing in this sub-clause (A) shall be interpreted to require GENERICO to obtain any Regulatory Approvals for which NEW ALPHA is responsible pursuant to Section 2.3; 
 (B) obtain and maintain such approvals and licenses as may be required by any Regulatory Authority or Legal Requirement for the manufacturing at the
Grand Island Facility of the Product or any Pipeline Product for commercial sale or clinical development in the territories of the European Union; provided, however, that nothing in this sub-clause (B) shall be interpreted to
require GENERICO to obtain any Regulatory Approvals for which NEW ALPHA is responsible pursuant to Section 2.3; 
 (C) obtain and
maintain such approvals and licenses as may be required by any Regulatory Authority or Legal Requirement for the manufacturing at the Grand Island Facility or Melrose Park Facility of the Product or any Pipeline Product for commercial sale or
clinical development in other jurisdictions as shall be reasonably requested by NEW ALPHA; provided, however, that nothing in this Section 2.2(C) shall require GENERICO to obtain any such approvals or licenses in any jurisdiction
unless both (a) doing so would not require (i) any material addition, upgrade or modification to any Facility (except where such addition, upgrade or modification would not otherwise have one of the effects described in clauses
(ii) and (iii) below, and NEW ALPHA agrees to reimburse GENERICO in accordance with clause (b) below in respect thereof), (ii) would not require any reallocation or diversion in any material respect of employees, space or other
resources of GENERICO and (iii) would not otherwise impair or disrupt in any material respect the ability of GENERICO to conduct its business or perform its obligations under this Agreement, and (b) NEW ALPHA agrees to reimburse GENERICO
for all incremental costs reasonably incurred by GENERICO and paid to third parties (with the 

  

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approval of NEW ALPHA not to be unreasonably withheld) as a result of obtaining any such approvals or licenses; and provided further that nothing in
this sub-clause (C) shall be interpreted to require GENERICO to obtain any Regulatory Approvals for which NEW ALPHA is responsible pursuant to Section 2.3; 
 (D) maintain such facilities, resources and personnel, and such industry expertise, as may be required for it to manufacture such units or batches of the Product and any Pipeline Product as may be required hereunder
and GENERICO will inform NEW ALPHA of any planned modifications of GENERICO’s facilities, equipment and processes, prior to implementation, that could result in the need for any additional Regulatory Approvals with respect to the Product or any
Pipeline Product (such notice to be in writing and with sufficient time to obtain any necessary Regulatory Approvals), and GENERICO and NEW ALPHA will reasonably agree on the manner and timing of such modifications; 
 (E) perform the Generico Manufacturing in compliance with the terms and conditions of this Agreement, the Specifications, cGMPs, the FDCA and any and all
other applicable Legal Requirements, and promptly provide NEW ALPHA with copies of any correspondence, including inspection reports, from Regulatory Authorities concerning GENERICO’s operation of the Facilities which could have any bearing in a
material respect upon this Agreement together with any responses thereto; 
 (F) implement, as soon as reasonably possible, any change or
modification to the manufacture or Specifications of the Product or any Pipeline Product that are required or recommended by any Regulatory Authority or required by cGMPs or Legal Requirements; provided, however, that NEW ALPHA shall
reimburse GENERICO for the reasonable out-of-pocket expenses incurred by GENERICO (with the approval of NEW ALPHA not to be unreasonably withheld) as a result of such change or modification to the extent that such change would not be necessary but
for the manufacturing of the Product or the Pipeline Products; 
 (G) implement, as soon as reasonably possible, any change or modification
to the manufacture or Specifications of the Product or any Pipeline Product that are requested by NEW ALPHA; provided, however, that nothing in this Section 2.2(G) shall require GENERICO to implement any such change or
modification unless both (a) doing so would not require (i) any material addition, upgrade or modification to any Facility (except where such addition, upgrade, or modification would not otherwise have one of the effects described in
clauses (ii) and (iii) below, and NEW ALPHA agrees to reimburse GENERICO in accordance with clause (b) below in respect thereof), (ii) would not require any reallocation or diversion in any material respect of employees, space or
other resources of GENERICO and (iii) would not otherwise impair or disrupt in any material respect the ability of GENERICO to conduct its business or perform its obligations under this Agreement, and (b) NEW ALPHA agrees to reimburse
GENERICO for all incremental costs reasonably incurred by GENERICO and paid to third parties (with the consent of NEW ALPHA not to be unreasonably withheld) as a result of any such change or modification; 
 (H) keep true, accurate and complete books, records, reports and accounts in connection with or relative to the Product and each Pipeline Product, and
the Generico 

  

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Manufacturing of the Product and the Pipeline Products, as well as any other books and records as may be required from time to time by Legal Requirements;

 (I) maintain batch records sufficient to trace the history of each batch, and representative samples from each batch of Product and
Pipeline Product manufactured hereunder, for record keeping, stability testing and other regulatory purposes in accordance with the Specifications and Legal Requirements; 
 (J) during the process of Generico Manufacturing, allow NEW ALPHA to undertake any Chemical Testing and other quality control measures reasonably requested by NEW ALPHA in order to comply with the Specifications and
requirements of any Regulatory Authority; and 
 (K) maintain each Facility in good working order and within cGMPs (e.g., qualification,
calibration, maintenance, validation), including critical systems (e.g., WFI, HVAC, clean steam, compressed gasses, etc.); and 
 (L)
maintain all manufacturing equipment (other than dedicated nanotechnology equipment) in good working order and within cGMPs (e.g., qualification, calibration, maintenance, validation). 
 2.3 NEW ALPHA or its licensees or designees will be solely responsible for obtaining and maintaining compliance with any Regulatory Approvals relating to
the importation, marketing, sale, clinical testing, distribution and use of the Product or any Pipeline Product. 
 2.4 NEW ALPHA, or any
designee of NEW ALPHA, will have the right at any time upon prior reasonable notice and during regular business hours to inspect and examine the parts of the Facilities used in connection with and relative to the Product and the Pipeline Products
and the Generico Manufacturing. Any such inspection or examination shall be scheduled at such time and conducted in such manner as to minimize disruption to GENERICO’s normal operations. 
 2.5 NEW ALPHA will have the right, upon prior reasonable notice and during regular business hours, to audit and inspect any and all documents and records
related to (A) GENERICO’s manufacture and supply of the Product and the Pipeline Products and (B) GENERICO’s performance under this Agreement, including GENERICO’s costs or expenses for which it is entitled to reimbursement
hereunder. GENERICO will also permit representatives of any Regulatory Authority, including, but not limited to, the FDA or its agents, to visit and inspect any and all facilities used in the Generico Manufacturing of the Product and the Pipeline
Products. This right of NEW ALPHA and the Regulatory Authorities includes access to audit any and all documents and records relating to GENERICO’s performance under this Agreement. 
 2.6 On or promptly after the Effective Date and, thereafter, by the end of the first week of each month of the Term, NEW ALPHA will send to GENERICO an
Estimated Generico Manufacturing Plan. The Parties acknowledge and agree that the Estimated Generico Manufacturing Plan is an estimate only and is not binding upon NEW ALPHA, except that the estimate for the next three months shall be binding.
GENERICO shall supply the quantity of the 

  

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Product and Pipeline Products reflected in Purchase Orders provided by NEW ALPHA from a particular Facility for a given month to the extent that such
Purchase Orders are for no more than (***) of the aggregate number of units of the Product from such Facility for such month reflected in the Estimated Generico Manufacturing Plan submitted at least ninety (90) days before the calendar month in
which such Purchase Order is submitted. GENERICO shall not be obligated to supply the quantity of the Product or any Pipeline Product earlier than seventy five (75) days following the placement of the Purchase Order for the Product or any
Pipeline Product. For the initial 90 days of this Agreement, GENERICO will supply the quantity of Product or Pipeline Product in accordance with orders placed by New Abraxis, LLC (or its predecessor Abraxis Bioscience, Inc.), which will, in
accordance with the next sentence, be consistent with the Annual Forecast for 2008. GENERICO shall supply quantities of the Product and any Pipeline Product during any month of the Term in calendar year 2007 or 2008 in accordance with orders placed
by New Abraxis, LLC (or its predecessors Abraxis Bioscience, Inc.) or Purchase Orders placed by NEW ALPHA as applicable; provided, that GENERICO shall not be obligated to supply units of Product and Pipeline Products from any Facility during
any such month in excess of (***) of the aggregate units of Product from such Facility reflected in the Annual Forecast for 2008. GENERICO shall not be obligated to supply in any year from a Facility a quantity of units of the Product and Pipeline
Products that exceeds by more than (***) the quantity of the Product indicated for such Facility in the Annual Forecast for such year. GENERICO shall, subject to Section 2.2 and this Section 2.6, use Reasonable Efforts to have the Generico
Manufacturing with respect to quantities of the Product and Pipeline Products subject to a Purchase Order (or order referred to in the prior sentences) performed at the Facility specified in the applicable Purchase Order (or order referred to in the
prior sentences) and otherwise in compliance with applicable Legal Requirements for the commercial sale or clinical testing of the Product or Pipeline Products in the Territory specified in the applicable Purchase Order; provided,
however, that if the Facility specified in the applicable Purchase Order is the only Facility qualified to manufacture the Product or any Pipeline Product pursuant to applicable Legal Requirements and the rules of any applicable Regulatory
Authority, then the Generico Manufacturing with respect thereto must be performed at the Facility specified in the Purchase Order. Until the Estimated Generico Manufacturing Plan is binding pursuant to this section, NEW ALPHA may substitute Product
for any Pipeline Product (or Pipeline Product for Product) that is reflected on NEW ALPHA’s Annual Forecast or Estimated Generico Manufacturing Plan, subject to all of the limitations in this Agreement. 
 2.7 In the event of any capacity constraints at any Facility or if GENERICO reasonably anticipates that there will be capacity constraints at any
Facility: 
 (A) GENERICO shall promptly notify NEW ALPHA in writing of any potential or actual capacity constraints, and GENERICO and NEW
ALPHA shall promptly meet to discuss how to address such capacity constraints (the period during which such capacity constraints are reasonably anticipated to prevent satisfaction of all Purchase Orders for which GENERICO would otherwise be required
to make delivery during such period, the “Proration Period”). At such meeting, GENERICO shall notify NEW ALPHA whether such capacity constraints will prevent GENERICO from satisfying Purchase Orders expected to be placed by NEW
ALPHA pursuant to the current Estimated Generico Manufacturing Plan. 
  

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 (B) In connection with manufacturing of the Product for delivery during the Proration Period, the
lyophilizers and filling lines approved for manufacturing the Product located at the Facilities shall be allocated equitably between the Parties according to the Proration Percentage. 
 (C) GENERICO shall not in any event be responsible for any failure to manufacture Product due to capacity constraints so long as it complies with this
Section 2.7 and uses Reasonable Efforts to eliminate, cure or overcome such capacity constraints and end the Proration Period as soon as reasonably practicable. 
 (D) If at any time the resources available for manufacturing under this Agreement (other than with respect to lyophilizer and filing line capacity) are less than the aggregate demand of both Parties, the resources
that are available shall be allocated equitably between the Parties. 
 2.8 Notwithstanding Section 2.7, if during the Term of this
Agreement: 
 (A) If as a result of capacity constraints and the application of the Proration Percentage in accordance with Section 2.7,
GENERICO is not required, in accordance with Section 2.7, to deliver sufficient units of the Product to fulfill the production forecasts set forth in the Estimated Generico Manufacturing Plan during any Proration Period (such Proration Period,
the “Supply Deficit Period”), NEW ALPHA may, at its sole option, elect to require GENERICO to manufacture and deliver additional units of the Product in an amount necessary to fulfill the production forecasts for such Supply Deficit
Period. 
 (B) If NEW ALPHA so elects to have GENERICO manufacture and deliver additional Product during a Supply Deficit Period pursuant to
Section 2.8(A), GENERICO shall be entitled to receive the following remuneration: After the end of each 90 day period during the Supply Deficit Period and at the end of the Supply Deficit Period, the Parties shall determine in good faith the
amount of net profits attributable to the sale of Generico Products (determined in accordance with generally acceptable accepted accounting principles as consistently applied by GENERICO) that GENERICO would have realized (but did not realize) with
respect to such 90-day or other period during the Supply Deficit Period had NEW ALPHA not exercised its option under Section 2.8(A), based on net profits attributable to the Generico Products realized by GENERICO during the most recent full
fiscal quarter ending prior to the Supply Deficit Period, plus any penalties incurred by GENERICO under GENERICO’s customer contracts as a result of NEW ALPHA’s exercise of its option under Section 2.8(A) less (***) of the total
amount charged to NEW ALPHA for the additional units of the Product manufactured during such Supply Deficit Period to fulfill the production forecasts. Within sixty (60) days after the mutual determination of such amount (the “Alternative
Compensation Amount”), NEW ALPHA shall pay to GENERICO an amount equal to such Alternative Compensation Amount. GENERICO shall use commercially reasonable efforts to maximize profits attributable to Generico Products in any Supply Deficit
Period and to minimize the Alternative Compensation Amount, including, without limitation, by using production capacity available to GENERICO to manufacture higher margin products and seeking to purchase Generico Products equal to the amount of any
shortfall from third-party suppliers. 
  

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 2.9 NEW ALPHA will provide, at its own cost, NEW ALPHA employees and personnel to supervise and
approve in writing, each stage of the manufacturing process related to the manufacture of the Product and the Pipeline Products. 
 2.10 In
addition to Generico Manufacturing, during the Term, GENERICO will provide NEW ALPHA the additional services listed on Schedule 2.10 in return by payment of NEW ALPHA of the amounts set forth on such Schedule 2.10 following receipt of
an invoice from GENERICO. Invoices will be issued by GENERICO promptly after each month-end during the Term of this Agreement, and payment shall be made, net 30 days after receipt by NEW ALPHA of an invoice, so long as the invoice complies with the
terms and conditions of this Agreement. 
 3. New Alpha Manufacturing. 
 3.1 NEW ALPHA will perform the New Alpha Manufacturing and will procure Chemical Ingredients and supply to GENERICO the Chemical Solution at an agreed schedule in amounts and times sufficient in order for GENERICO to
meet its obligations under Section 2. 
 3.2 NEW ALPHA will for the New Alpha Manufacturing in good faith use Reasonable Efforts to:

 (A) have such resources and personnel, and such industry expertise, as may be required for it to perform the New Alpha Manufacturing as
required hereunder; 
 (B) perform the New Alpha Manufacturing in compliance with the terms and conditions of this Agreement, the
Specifications, cGMPs, the FDCA and any and all other applicable Legal Requirements; 
 (C) keep true, accurate and complete books, records,
reports and accounts in connection with the New Alpha Manufacturing as well as any other books and records as may be required from time to time by any applicable Legal Requirement; 
 (D) maintain all nanotechnology specific equipment in good working order and within cGMPs (e.g., qualification, calibration, maintenance, validation);
and 
 (E) arrange for pickup and transportation of finished Product and Pipeline Products; provided, that, during the period in which the
Warehouse Services Agreement is in effect, GENERICO will in good faith use Reasonable Efforts to arrange for such pickup and transportation. 
 3.3 Following completion of Generico Manufacturing, NEW ALPHA will perform Chemical Testing as required by applicable Legal Requirements. Section 6.1 shall govern release of any Product or Pipeline Product. 
 3.4 GENERICO, or any designee of GENERICO, will have the right at any time upon prior reasonable notice and during regular business hours to inspect and
examine NEW ALPHA’s portions of the Facilities used in connection with and relative to the Product and the Pipeline Products and the New Alpha Manufacturing thereof. Any such inspection and 

  

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examination shall be scheduled at such time and conducted in such manner as to minimize disruption to NEW ALPHA’s normal operations. 
 3.5 GENERICO will have the right, upon prior reasonable notice and during regular business hours, to audit and inspect any and all documents and records
related to NEW ALPHA’s performance under this Agreement, including NEW ALPHA’s costs and expenses for which it is entitled to reimbursement hereunder. NEW ALPHA will also permit representatives of any Regulatory Authority, including, but
not limited to, the FDA or its agents, to visit and inspect NEW ALPHA’s portions of the Facilities used in the New Alpha Manufacturing of the Product and the Pipeline Products. This right of GENERICO and the Regulatory Authorities includes
access to audit any and all documents and records relating to NEW ALPHA’s performance under this Agreement. Sections 3.4 and 3.5 shall not be interpreted to require NEW ALPHA to provide or disclose any documents, records or other information to
the extent constituting Proprietary Information. 
 3.6 NEW ALPHA shall, at its option (as determined in its sole discretion), perform New
Alpha Manufacturing with respect to GENERICO’s products, pending products and products under development as requested from time to time by GENERICO. The scope, timing and cost for any such New Alpha Manufacturing shall be as agreed between NEW
ALPHA and GENERICO (in their sole discretion). 
 4. Price and Payment. 
 4.1 With the issuance by NEW ALPHA of a Purchase Order, NEW ALPHA shall designate whether (and, as applicable, what portion of) the ordered Product shall be used for commercial sale, clinical supply, validation,
stability or other uses, and each Purchase Order with respect to quantities of the Product that will be commercially sold, shall indicate the Facility at which the Generico Manufacturing shall occur and the Territory in which such quantities will be
sold. The price per unit of the Product, and the price per batch of any Pipeline Product, to be charged by GENERICO with respect to each unit or batched delivered by GENERICO shall be as set forth in Schedule 4.1. The price of the Product and
any Pipeline Product will not include delivery of the Product or Pipeline Product to NEW ALPHA or any of its distributors. The risk of loss of any Product will transfer FOB shipping point (i.e., GENERICO manufacturing Facility). 

4.2 GENERICO will issue an invoice to NEW ALPHA for each Purchase Order, based upon and reflecting the applicable price. Invoices will be issued upon
(i) written release of the Product or Pipeline Product by NEW ALPHA and (ii) delivery to NEW ALPHA’s common carrier for delivery. Payment shall be made, net 30 days after receipt by NEW ALPHA of an invoice, so long as the invoice
complies with the terms and conditions of this Agreement. Notwithstanding the foregoing, payment with respect to Product or Pipeline Products that are Rejected Products shall be paid in accordance with Section 6. 
 5. Regulatory Approval. 
 5.1 GENERICO will use
Reasonable Efforts to cooperate with NEW ALPHA and its licensees with respect to obtaining all Regulatory Approvals relating to the Product and the 

  

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Pipeline Products in any Territory, subject to Section 2.2(C). Without limiting the foregoing, GENERICO will use Reasonable Efforts to provide NEW ALPHA
with such data monitoring support and data analysis support related to manufacturing issues as NEW ALPHA may reasonably request. All data and information relating to such support with respect to the Product or any Pipeline Product will, if it
relates solely to the Product or any Pipeline Product, be the exclusive property of NEW ALPHA and may be used by NEW ALPHA, at no cost to NEW ALPHA, in such manner as NEW ALPHA determines. 
 5.2 GENERICO will use Reasonable Efforts to assist NEW ALPHA in the preparation and submission of a chemistry, manufacturing and controls (CMC) section
and plant master file or other regulatory documents to any Regulatory Authority as reasonably requested by NEW ALPHA. Notwithstanding anything to the contrary in this Section 5.2, all CMC information that relates solely to the Product or any
Pipeline Product will be owned exclusively by, and will be the exclusive Proprietary Information of, NEW ALPHA and any CMC information not relating solely to the Product or any Pipeline Product will, to the extent relating to the Product or any
Pipeline Product, be owned by NEW ALPHA and will be Proprietary Information of NEW ALPHA and may be used by GENERICO, at no cost to GENERICO, subject to Section 11 hereof, in connection with the requirements of any Regulatory Authority.

 5.3 NEW ALPHA will use Reasonable Efforts to cooperate with GENERICO with respect to obtaining and maintaining all Regulatory Approvals
relating to manufacturing of the Product and the Pipeline Products for commercial sale or clinical development in any Territory. Without limiting the foregoing, NEW ALPHA will use Reasonable Efforts to provide GENERICO with such data monitoring
support and data analysis support related to the Generico Manufacturing of the Product and the Pipeline Products as GENERICO may reasonably request; provided, however, that nothing in this Section 5.3 shall be interpreted to
require NEW ALPHA to provide or disclose any documents, records or other information that constitutes Proprietary Information. All data and information relating to such support with respect to the Product and any Pipeline Product will, to the extent
it relates to the Product or any Pipeline Product, be the property of NEW ALPHA, and will be the Proprietary Information of NEW ALPHA, and any CMC information not relating solely to the Product or any Pipeline Product will, to the extent relating to
the Product or any Pipeline Product, be owned by NEW ALPHA, and will be Proprietary Information of NEW ALPHA, and may be used by GENERICO, at no cost to GENERICO, subject to Section 11 hereof, in connection with the requirements of any
Regulatory Authority. 
 6. Rejected Product. 
 6.1 NEW ALPHA will inspect pursuant to New Alpha Review and Release, and GENERICO will inspect pursuant to Generico Manufacturing, each batch of Product and Pipeline Product for compliance with the Specifications, cGMPs, the FDCA and any
and all other applicable Legal Requirements. If after inspection of Product or Pipeline Product NEW ALPHA notifies GENERICO, or GENERICO notifies NEW ALPHA, that any Product or Pipeline Product is non-compliant, as determined by such Party’s
testing and inspection of the Product or Pipeline Product, the Parties will in good faith attempt to mutually determine whether the failure of the Product or Pipeline Product, as applicable, to comply is a result of Generico Manufacturing or New
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provided, however, that the provisions of Section 6.2 will not apply (and thus GENERICO will have no responsibility or liability relating
to any non-compliance) with respect to any Pipeline Products in clause (A) or (B) of such definition unless, in any quarter beginning with the first quarter ending after the Effective Date, (***) of such Pipeline Products are
non-compliant; provided further, that Pipeline Products shall only be determined non-compliant if GENERICO fails to perform Generico Manufacturing according to the Specifications for such Pipeline Product provided by NEW ALPHA. 
 6.2 If the Parties are unable to mutually determine whether the failure of the Product or Pipeline Products to comply is a result of Generico
Manufacturing or New Alpha Manufacturing within 60 days of the delivery of a rejection notice by either Party, such dispute will be resolved by an independent, FDA-approved testing organization or consultant of recognized repute within the U.S.
pharmaceutical industry, to be mutually designated by the Parties, the designation of which will not be unreasonably withheld or delayed by either Party. To the extent the Parties are unable to agree on a testing organization or consultant, each
Party will designate one such entity and those two entities will agree on a mutually acceptable testing entity. The testing entity of the Product shall determine the source of the non-compliance (i.e., Generico Manufacturing or
New Alpha Manufacturing). Both Parties will provide the testing entity with such information as the testing entity reasonably requires in order to make such determination; provided, however, that either Party may, to the extent it
deems necessary, withhold from the independent third party testing entity any Proprietary Information. Any determination by the independent third party testing entity will be final and binding upon the Parties. If the independent third party testing
entity states that it is unable to make a determination as a result of NEW ALPHA’s or GENERICO’s, as applicable, decision to not disclose Proprietary Information, the non-compliance of the applicable Rejected Product will be deemed to have
resulted from (A) New Alpha Manufacturing in the event NEW ALPHA is the non-disclosing Party or (B) Generico Manufacturing in the event GENERICO is the non-disclosing Party. If the independent third party testing entity’s
determination is inconclusive, then the non-compliance of such Rejected Product will be deemed to have resulted 50% from New Alpha Manufacturing and 50% from Generico Manufacturing. NEW ALPHA shall have the final determination over the disposition
of any Product or Pipeline Product; provided, that no Product or Pipeline Product shall be released if either Party has determined that such Product or Pipeline Product is non-compliant. The Parties agree to handle the costs associated with
Rejected Product manufactured for NEW ALPHA as follows: 
 (A) To the extent that a Rejected Product is determined to be such as a
result of the Generico Manufacturing or a failure or deficiency of the Generico Manufacturing, then GENERICO will replace the Rejected Product as promptly as practicable (if requested by NEW ALPHA) and, subject to clause (B) below, no payment
shall be required to be made by NEW ALPHA in respect of such Rejected Product and any payment that may have been made shall, at NEW ALPHA’s election, be refunded by GENERICO within 30 days of such determination or credited to any amounts then
owing by NEW ALPHA to GENERICO hereunder; provided, however, that GENERICO will not be obligated to replace and will not have any liability to NEW ALPHA in respect of the Rejected Product, unless the batches of the Rejected Product
resulting from the Generico Manufacturing are more than (***) of the total batches of Product (or (***) of the total batches for Pipeline Products) manufactured for NEW ALPHA in any calendar year during the Term. To the extent the batches of
Rejected Product exceed such (***) 

  

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or (***), as applicable, GENERICO shall reimburse NEW ALPHA for the Chemical Ingredients and Materials used in the New Alpha Manufacturing of such excess
Rejected Product. 
 (B) To the extent that Rejected Product is determined to be such as a result of the New Alpha Manufacturing or a failure
or deficiency of the New Alpha Manufacturing, then GENERICO shall invoice NEW ALPHA for the Product or Pipeline Product within 30 days of such determination. Payment shall be made, net 30 days after receipt by NEW ALPHA of an invoice, so long as the
invoice complies with the terms and conditions of this Agreement. 
 (C) In the event that the reason for the Rejected Product in part
results from the Generico Manufacturing or a failure or deficiency of the Generico Manufacturing and in part from the New Alpha Manufacturing or a failure or deficiency of the New Alpha Manufacturing, then the costs of the Product or Pipeline
Products, as applicable, shall be allocated in an equitable manner between the Parties. 
 7. Adverse Experience Reporting. Each Party will promptly
report to the other Party any information of which it becomes aware concerning any adverse drug experience in connection with the use of the Product, including the incidence and the severity thereof. Each Party shall be responsible for reporting
adverse experiences in accordance with applicable Legal Requirements; provided, however, that NEW ALPHA will bear all reasonable expenses incurred by GENERICO and NEW ALPHA in connection therewith. NEW ALPHA will provide to GENERICO
copies of any reports submitted to the FDA and/or Regulatory Authority relating to any adverse drug experiences that are reasonably significant. GENERICO shall be responsible for receiving and documenting any complaint regarding the Product, as well
as forwarding the complaint information to the applicable Facility quality unit and responding to the customer. 
 8. Recalls. 
 8.1 Each Party shall promptly notify the other if such Party believes that a recall, withdrawal or field correction (each, a “Recall”) of
the Product or any Pipeline Product may be necessary or advisable. 
 8.2 NEW ALPHA shall be responsible for the Recall decision,
notification of Regulatory Authorities, the Recall strategy and generation of the final Recall letter. During the period in which the Warehouse Services Agreement is in effect, if any, GENERICO will be responsible for executing the Recall,
reconciling Product, preparing and submitting Recall status reports and termination requests to applicable Regulatory Authorities with respect to Recall of the Product and any Pipeline Product. Following termination of the Warehouse Services
Agreement, NEW ALPHA will be responsible for all Recall activities with respect to Recall of the Product and any Pipeline Product that was not previously shipped from the Premises (as defined in the Warehouse Services Agreement) by GENERICO. In
either case, NEW ALPHA shall (subject to Section 8.3) bear all expenses incurred by GENERICO (with the consent of NEW ALPHA not to be unreasonably withheld) and NEW ALPHA in connection with such Recall. Each of the Parties will reasonably
cooperate with the other Party in connection with any Recall. Each Party will maintain complete and accurate Recall records relating to the Product or any Pipeline Product for any periods that are required by any Legal Requirements. 
  

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 8.3 In the event that it is determined that any Product or Pipeline Product is recalled as a result
of GENERICO’s gross negligence, bad faith, intentional misconduct or intentional breach of this Agreement, then GENERICO shall bear all of the costs and expenses of such Recall, including without limitation expenses related to communications
and meetings with all required Regulatory Authorities, customer credits for recalled stock, the cost of notifying customers and costs associated with shipment of recalled Product or Pipeline Product from customers and shipment of an equal amount of
replacement Product or Pipeline Product to those customers, subject to Sections 12.2 and 12.8. In the event that any Product or Pipeline Product is recalled other than as a result of GENERICO’s gross negligence, bad faith, intentional
misconduct or intentional breach of this Agreement (or for which the liability would exceed the limitations set forth in Section 12.9), then NEW ALPHA shall bear all of the costs and expenses of such Recall, including without limitation
expenses related to communications and meetings with all required Regulatory Authorities, expenses of replacement stock, the cost of notifying customers and costs associated with shipment of recalled Product or Pipeline Product from customers and
shipment of an equal amount of replacement Product to those customers. In the event that the reason for any Recall of Product hereunder is in part the responsibility of GENERICO as described herein and in part the responsibility of NEW ALPHA as
described herein, then the expenses shall be allocated in an equitable manner between the Parties. 
 8.4 If the Parties are unable to
mutually agree on the source cause of the Recall within 5 days of the event causing the Recall, such dispute will be resolved in the same manner as set forth in Section 6.2. The fees and expenses of the testing entity making the determination
will be paid by the Party against which the determination is made. NEW ALPHA shall have the final determination over the disposition of any Recalled Product. 
 9. Product Liability. 
 9.1 For so long as NEW ALPHA is commercially marketing and selling the Product, or conducting the New
Alpha Manufacturing with respect to the Product or any Pipeline Product, it shall maintain product liability insurance with respect to the Product and the Pipeline Products, as applicable, with a reputable carrier, in the amounts set forth in
Exhibit B, naming GENERICO and its Affiliates as additional insureds. 
 9.2 For so long as GENERICO is performing Generico
Manufacturing with respect to the Product or any Pipeline Product, it shall maintain product liability insurance with respect to the Product and the Pipeline Products, with a reputable carrier, in the amounts set forth in Exhibit C
hereto, naming NEW ALPHA and its Affiliates as additional insureds. 
 9.3 Each Party must notify the other Party as promptly as practicable
if a Product Liability Claim is commenced or threatened against any Party. Each Party must cooperate with the other Party in connection with any Product Liability Claim that is commenced or threatened against the other Party. 
 9.4 If a Product Liability Claim is asserted against both Parties, each Party will have the right, at its own cost (subject to Section 9.6), to
designate counsel to defend itself in such Product Liability Claim. If a Product Liability Claim is brought against one Party but not the other Party, the named Party will (subject to Section 9.5) have absolute control of litigation, except
that: 
  

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 (A) the other Party may appoint counsel to participate in the defense of such Product Liability Claim
if the named Party reasonably determines that the participation would not adversely affect the attorney-client privilege; and 
 (B) if the
litigation could reasonably be expected to have an adverse effect on the development and commercialization of the Product or any Pipeline Product, the named Party will consult with the other Party regarding the conduct of the litigation if the named
Party reasonably determines that the cooperation would not adversely affect the attorney-client privilege. 
 9.5 Neither Party shall agree
to a settlement of any Product Liability Claim without the consent of the other Party, in that other Party’s absolute discretion, if the settlement: 
 (A) admits any liability of the other Party or any of its Affiliates with respect to such Product Liability Claim; 
 (B) does not release the other Party and its Affiliates from all liabilities and obligations with respect to such Product Liability Claim; or 
 (C) imposes non-monetary damages or injunctive or other equitable relief against the other Party or any of its Affiliates. 
 9.6 NEW ALPHA will be solely responsible for any Damages payable by NEW ALPHA or GENERICO to third parties following final judgment or settlement of any
Product Liability Claim arising from use or sales of the Product (collectively, “Product Liability Costs”), and must promptly pay or reimburse GENERICO if GENERICO pays or incurs any Product Liability Costs, subject to the
immediately following sentence. GENERICO will be responsible for any Product Liability Costs to the extent they arise from or as a result of the negligence, bad faith, intentional misconduct or intentional breach of this Agreement by GENERICO, and
must promptly pay or reimburse NEW ALPHA if NEW ALPHA pays or incurs any Product Liability Costs that arise from or relate to GENERICO’s gross negligence, bad faith, intentional misconduct or intentional breach of this Agreement, subject to
Sections 12.2 and 12.8. 
 10. Term and Termination. 
 10.1 This Agreement will commence on the Effective Date and will continue through December 31, 2011 (the “Term”). The Term shall be automatically extended for an additional year until
December 31, 2012 upon the occurrence of either (or both) of (i) GENERICO’S exercise of its option to extend the term of that certain Lease, dated as of the date hereof, between GENERICO and New Abraxis, LLC for the Melrose Park
Facility (the “Melrose Park Lease”), so that the Melrose Park Lease expires on December 31, 2012 or (ii) New Abraxis, LLC’s exercise of its option to extend the term of that certain Lease, dated as of the date hereof,
between GENERICO and New Abraxis, LLC for the Grand Island Facility (the “Grand Island Lease”), so that the Grand Island Lease expires on December 31, 2012. 
 10.2 The non-defaulting Party may terminate this Agreement if the other Party commits a material breach or default (“Breach”) under this
Agreement, which Breach is not remedied within 60 days after the receipt of written notice of the Breach by the non-defaulting 

  

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Party (except as to the payment of money by NEW ALPHA, for which the cure period will be 20 days) and which Breach is continuing at the time of termination.
Notwithstanding the foregoing, if the Breach is not curable in 60 days, and the breaching or defaulting Party in good faith notifies the other Party in writing prior to the 60 days that it is initiating cure of the Breach, and initiates cure of such
Breach within 60 days and in good faith continues to attempt to cure the Breach, then this Agreement shall not be terminated pursuant to this Section 10.2. The right of a Party to terminate this Agreement provided in this Section 10.2 will
not be affected in any way by its waiver of, or failure to take such action with respect to, any previous Breach. 
 10.3 This Agreement may
be terminated immediately by either NEW ALPHA or GENERICO if the other Party: 
 (A) does not pay its debts generally as they become due, or
is unable to pay its debts generally as they become due; 
 (B) has or has instituted against it any proceeding seeking to adjudicate it
bankrupt or insolvent, or seeking liquidation, winding up, reorganization, arrangement, adjustment, protection, relief or composition of it or its debts under any law relating to bankruptcy, insolvency or reorganization or relief of debtors;

 (C) makes a general assignment for the benefit of creditors; 
 (D) seeks the entry of an order for relief or the appointment of a receiver, liquidator, sequestrator, trustee, custodian or similar official for it; or

 (E) takes advantage of any other law or procedure for the protection of creditors. 
 10.4 Termination is not the sole remedy under this Agreement, and whether or not termination is effected, all other remedies remain available to each
Party. 
 10.5 NEW ALPHA may terminate this Agreement for any reason at any time by giving GENERICO not less than 3 months prior written
notice. 
 10.6 Upon termination or expiration of this Agreement for whatever reason, the Parties shall reasonably cooperate with each other
to transfer to NEW ALPHA all Chemical Ingredients, Materials, Components, finished goods inventory, retained samples, stability samples and work in process in the possession, custody or control of GENERICO (and NEW ALPHA shall reimburse GENERICO for
its reasonable expenses occurred in procuring and manufacturing such items) and GENERICO shall use Reasonable Efforts to cooperate with NEW ALPHA with respect to technology transfer matters for the Product and Pipeline Products. 
 11. Confidentiality. 
 11.1 Each Party recognizes that
the other Party holds its Proprietary Information as important. In particular, each Party recognizes that the other Party’s Proprietary Information (and the confidential nature thereof) is critical to the other Party’s business and that
neither Party 

  

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would enter into this Agreement without assurance that such information and the value thereof will be protected as provided in this Section 11 and
elsewhere in this Agreement. 
 11.2 Each Party must, therefore: 
 (A) hold the other Party’s Proprietary Information in confidence and take reasonable precautions to protect the Proprietary Information (including,
without limitation, no less than all precautions that it employs with respect to its own confidential materials); 
 (B) except as required
by law, regulation or legal process, not divulge (except pursuant to a sublicense expressly authorized in this Agreement) the other Party’s Proprietary Information or any information derived therefrom to any third person; provided,
however, that if a Party is required to make any such disclosure of the other Party’s Proprietary Information, such Party shall give reasonable advance notice to the other Party of such required disclosure and will use reasonable efforts
consistent with prudent business judgment to secure confidential treatment of such Proprietary Information prior to its disclosure (whether through protective orders or confidentiality agreements or otherwise); and provided, further
that if GENERICO is required to disclose NEW ALPHA’s Proprietary Information that constitutes CMC information, GENERICO will provide NEW ALPHA with prompt written notice so that NEW ALPHA may seek, at NEW ALPHA’s expense, an appropriate
protective order to avoid disclosure of such Proprietary Information. If NEW ALPHA has attempted and failed to obtain a protective order and GENERICO is, upon advice of its counsel, compelled to disclose Proprietary Information related to CMC
information to prevent liability for contempt or other censure or penalty or other liability, GENERICO may disclose such portion of the Proprietary Information that is required to be disclosed, In such case, GENERICO will use Reasonable Efforts (at
NEW ALPHA’s expense) so that confidential treatment will be accorded to any Proprietary Information so disclosed; and 
 (C) not make
any use whatsoever at any time of the other Party’s Proprietary Information except for purposes of and expressly authorized in this Agreement. 
 11.3 Any employee or contractor given access to any Proprietary Information must have a legitimate “need to know” and must be bound in writing to maintain the confidence of information to which it is given access. 
 11.4 Without granting any right or license, the disclosing Party agrees that the foregoing restrictions will not apply with respect to information that
the receiving Party is able to demonstrate by competent evidence: 
 (A) is in or (through no improper action or inaction by the receiving
Party or any Affiliate of the receiving Party or their agents or employees) enters the public domain (and is readily available without substantial effort); 
 (B) was rightfully disclosed to it by another Person without restriction; or 
 (C) was independently
developed by it by Persons without access to such information and without use of any of the disclosing Party’s Proprietary Information. 
  

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 11.5 Each Party’s obligations under this Section 11 will terminate five years after the
date of termination or expiration of this Agreement. The Parties recognize and acknowledge that prior to the Effective Date of this Agreement, each Party has received the other Party’s Proprietary Information and each hereby agrees to protect
the Proprietary Information to the same extent as set forth in this Section 11. 
 11.6 Immediately upon termination or expiration of
this Agreement, each Party will turn over to the other Party all Proprietary Information of the other Party and all documents or media containing any Proprietary Information and any and all copies or extracts thereof. 
 11.7 Each Party acknowledges and agrees that due to the unique nature of Proprietary Information, there may be no adequate remedy at law for any breach
of a Party’s obligations under this Section 11, that any breach may result in irreparable harm to the disclosing Party, and therefore, that upon any breach or any threat of breach, the disclosing Party will be entitled to appropriate
equitable relief (without the posting of any bond) in addition to whatever remedies it might have at law in connection with any breach or enforcement of the receiving Party’s obligations under this Agreement or the unauthorized use or release
of any Proprietary Information. 
 11.8 GENERICO hereby acknowledges that it and its Affiliates do not have, and shall not acquire by virtue
of this Agreement, any rights to or under any goodwill, trademark, tradename, copyright, patent or other intellectual property of NEW ALPHA or any of its Affiliates, nor in any of NEW ALPHA’s or its Affiliates’ trademarks or trade names
appearing on the label or packaging materials of the Product or any of the Pipeline Products. GENERICO agrees to do nothing by act or omission which would impair NEW ALPHA’s or its Affiliates’ rights, ownership and title in the
aforementioned. 
 11.9 NEW ALPHA hereby acknowledges that it does not have, and shall not acquire by virtue of this Agreement, any rights to
or under any goodwill, trademark, tradename, copyright, patent or other intellectual property of GENERICO, nor in any of GENERICO’s trademarks or trade names appearing on the label or packaging materials of the Product or any Pipeline Products.
NEW ALPHA agrees to do nothing by act or omission which would impair GENERICO’s or its Affiliates’ rights, ownership and title in the aforementioned. 
 11.10 If either Party becomes aware of any product or activity of any third Party that involves or may involve infringement or other violation of any Technology, that Party must promptly notify the other Party in
writing of the infringement or violation. NEW ALPHA may in its discretion take or not take whatever action it believes is appropriate. GENERICO will fully cooperate with NEW ALPHA with respect to bringing any action, including joining as a party to
the suit, if necessary, supplying essential documentary evidence and making essential witnesses then in its employ available, in each case only to the extent that such cooperation would not interfere with the operation of GENERICO’s business
and subject to the reimbursement of GENERICO for reasonable out-of-pocket expenses incurred by it in connection with such cooperation. 
  

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 12. Indemnification. 
 12.1 GENERICO agrees, subject to Sections 12.8 and 12.9, to indemnify, defend and hold harmless NEW ALPHA and its Affiliates and their respective officers, directors, employees and agents from any Damages incurred by
or assessed against them resulting from a third party claim caused by or alleged to be caused by: 
 (A) GENERICO’s gross negligence, bad
faith, intentional misconduct or intentional failure to perform any of its obligations under this Agreement; and 
 (B) any Product Liability
Claim arising from the gross negligence or bad faith of, or intentional misconduct or intentional breach of this Agreement by, GENERICO or any GENERICO Affiliate. 
 12.2 NEW ALPHA agrees to indemnify, defend and hold harmless GENERICO, its Affiliates, and their officers, directors, employees and agents (the “GENERICO Indemnified Parties”) from any Damages
incurred by or assessed against them resulting from a third party claim caused by or alleged to be caused by: 
 (A) NEW ALPHA’s failure
to perform any of its obligations under this Agreement; 
 (B) any Product Liability Claim arising from the (i) negligence, fraud or
intentional misconduct of NEW ALPHA or any NEW ALPHA Affiliates or (ii) the New Alpha Manufacturing or any failure or deficiency in the New Alpha Manufacturing; 
 (C) any claim that the manufacture, use or sale of the Product or any Pipeline Product infringes a patent or any other proprietary right of a third party; 
 (D) any Recall, Product Liability Claim or other third-party claim (i) not arising from the gross negligence or bad faith of, or intentional
misconduct or intentional breach of this Agreement by, the GENERICO Indemnified Parties or (ii) to the extent the liability of the GENERICO Indemnified Parties therefrom would result in the GENERICO Indemnified Parties being subject to
liability for which GENERICO is not responsible under Section 12.9. 
 12.3 If any Party entitled to be indemnified pursuant to this
Section 12 (an “Indemnified Party”) receives notice of the assertion by any Person of any claim or of the commencement by any such Person of any Action (any such claim or Action being referred to herein as an
“Indemnifiable Claim”) with respect to which another Party hereto (an “Indemnifying Party”) is or may be obligated to provide indemnification, the Indemnified Party must promptly notify the Indemnifying Party in
writing (the “Claim Notice”). The failure to provide such notice will not relieve or otherwise affect the obligation of the Indemnifying Party to provide indemnification hereunder, except to the extent that any Damages directly
resulted or were caused by such failure. 
 12.4 The Indemnifying Party will have 30 days after receipt of the Claim Notice to undertake,
conduct and control, through counsel of its own choosing and at its expense, the 

  

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settlement or defense of the claim, and the Indemnified Party will cooperate with the Indemnifying Party in connection with the settlement or defense, if:

 (A) the Indemnifying Party permits the Indemnified Party to participate in the settlement or defense through counsel chosen by the
Indemnified Party (subject to the consent of the Indemnifying Party, which consent shall not be unreasonably withheld); 
 (B) the fees and
expenses of such counsel will not be borne by the Indemnifying Party; and 
 (C) the Indemnifying Party does not settle any Indemnifiable
Claim without the Indemnified Party’s consent. So long as the Indemnifying Party is vigorously contesting any Indemnifiable Claim in good faith, the Indemnified Party may not pay or settle the claim without the Indemnifying Party’s
consent, which consent shall not be unreasonably withheld. 
 12.5 If the Indemnifying Party does not notify the Indemnified Party within 30
days after receipt of the Claim Notice that it elects to undertake the defense of the Indemnifiable Claim described in the Claim Notice, the Indemnified Party has the right to contest, settle or compromise the Indemnifiable Claim in the exercise of
its reasonable discretion. However, the Indemnified Party must notify the Indemnifying Party of any compromise or settlement of any such Indemnifiable Claim. 
 12.6 Notwithstanding anything in this Section 12 to the contrary, GENERICO is not entitled to assume the defense for any Indemnifiable Claim (and will be liable for the reasonable fees and expenses incurred by
the Indemnified Party in defending the claim) if the Indemnifiable Claim seeks an order, injunction or other equitable relief (or other relief for other than money damages) against NEW ALPHA or its Affiliates which NEW ALPHA determines, after
conferring with its counsel, cannot be separated from any related claim for money damages and which, if successful, would adversely affect the commercialization of the Product or any Pipeline Product. However, if an equitable relief portion of the
Indemnifiable Claim can be separated from that for money damages, GENERICO may assume the defense of the portion relating to money damages. 
 12.7 In calculating any amount that any Indemnifying Party is required to pay an Indemnified Party in respect of Damages provided under this Agreement, such amount shall be (A) reduced to take into account any net tax benefit realized
by the Indemnified Party arising from the incurrence or payment by the Indemnified Party of such Damages and (B) increased to take into account any net tax cost incurred by the Indemnified Party as a result of the receipt or accrual of payments
hereunder (grossed-up for such increase), in each case determined by treating the Indemnified Party as recognizing all other items of income, gain, loss, deduction or credit before recognizing any item arising from such Damages (provided that if the
tax benefit or cost is realized in a tax period following the period in which the indemnity payment is made, the tax benefit or cost amount (as the case may be) shall be paid over when realized). 
 12.8 NOTWITHSTANDING ANYTHING TO THE CONTRARY HEREIN, NEITHER PARTY WILL BE LIABLE HEREUNDER FOR MONETARY DAMAGES UNDER ANY CONTRACT, NEGLIGENCE, STRICT
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EQUITABLE THEORY FOR ANY SPECIAL, INDIRECT, INCIDENTAL OR CONSEQUENTIAL DAMAGES, INCLUDING WITHOUT LIMITATION, LOSS OF PROFITS FROM THE USE OF (OR INABILITY
TO USE) THE TECHNOLOGY, THE DEVELOPMENT OR COMMERCIALIZATION OF THE PRODUCT OR OTHERWISE IN CONNECTION WITH, OR ARISING OUT OF, THIS AGREEMENT, OTHER THAN WITH RESPECT TO DAMAGES FOR GENERICO EXTRAORDINARY FAILURE (as defined in Section 12.9)

 12.9 Notwithstanding anything herein to the contrary, in no event will the GENERICO Indemnified Parties have any liability to NEW ALPHA or
any of its Affiliates, or to any third party in connection with this Agreement, for monetary Damages in excess of $100 million in the aggregate, except to the extent that such Damages are the result of (A) one of GENERICO’s (or one of its
parent entity’s) executive officers, in bad faith, affirmatively instructing employees of GENERICO to materially breach GENERICO’s obligation to manufacture the Product or any Pipeline Product under this Agreement or (B) any
intentional failure by GENERICO, in bad faith, to cure any material breach of GENERICO’s obligation to manufacture the Product or any Pipeline Product under this Agreement (which is capable of being cured) following notice thereof in accordance
with Section 15.3 (if such breach is not cured within a reasonable period of time following receipt of such notice of such breach) (any of the occurrences set forth in sub clauses (A) and (B) of this Section 12.9,
“GENERICO Extraordinary Failure”). 
 13. Management Fee. NEW ALPHA will pay GENERICO a facility management fee (the
“Management Fee”) equal to $3,000,000 for each of the 2008, 2009 and 2010 calendar years, or a total of $9,000,000, such payment to be made within 30 days following the end of the applicable calendar year. The Management Fee shall
be in addition to, and not in lieu of, any amounts otherwise payable under this Agreement. In addition, the Management Fee shall be reduced to the extent employees of GENERICO at the Melrose Park Facility are transferred to NEW ALPHA as more fully
described in Section 14.5 below. 
 14. Melrose Park and Grand Island Facilities. 
 14.1 FDA Compliance. 
 (A) Each of NEW
ALPHA and GENERICO shall cooperate reasonably and in good faith with the other Party to develop a mutually acceptable plan to modernize the Melrose Park Facility as requested or required by the FDA or that, in both Parties’ reasonable judgment,
are necessary to maintain FDA Regulatory Approvals (the “FDA Modernization Plan”). All costs and expenses contemplated by the FDA Modernization Plan shall be borne by NEW ALPHA. The scope and timing of implementation of, and
expenditures under, the FDA Modernization Plan shall be mutually determined in good faith between the Parties. 
 (B) GENERICO will, in good
faith, execute the actions contemplated by the FDA Modernization Plan, subject to NEW ALPHA’s review and approval. NEW ALPHA shall reimburse GENERICO for all out-of pocket costs to third parties reasonably incurred (with the approval of NEW
ALPHA not to be unreasonably withheld) in connection with GENERICO’s performance of such actions. In connection with such actions, GENERICO will not in any event be obligated to incur incremental shutdown time outside the ordinary course of its
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reduce in any material respect production capacity available for producing Generico Products (or, without the consent of NEW ALPHA, the Product or any
Pipeline Product) or otherwise impact or disrupt in any material respect GENERICO’s or NEW ALPHA’s business. 
 14.2 EU
Compliance. 
 (A) To the extent requested by NEW ALPHA, GENERICO shall cooperate reasonably and in good faith in connection with NEW
ALPHA’s preparation of a plan to obtain necessary Regulatory Approvals from the EMEA with respect to the Melrose Park Facility (the “Melrose Park EU Plan”). All costs and expenses contemplated by the Melrose Park EU Plan shall
be borne by NEW ALPHA (unless GENERICO initiates plans to commercialize its products or product candidates in Europe, in which case the Parties shall allocate the costs and expenses contemplated by the Melrose Park EU Plan between them equitably in
good faith). Subject to Section 14.2(B) below, the scope and timing of implementation of, and expenditures under, the Melrose Park EU Plan shall be in the sole discretion of NEW ALPHA. 
 (B) During the term of the Melrose Park Lease, GENERICO will, in good faith, complete the actions required under the Melrose Park EU Plan as soon as
reasonably practicable following the Effective Date. In connection with such actions, GENERICO will not in any event be obligated to incur incremental shutdown time outside the ordinary course of its business, reduce in any material respect
production capacity available for producing Generico Products (or, without the consent of NEW ALPHA, the Product or any Pipeline Product) or otherwise impact or disrupt in any material respect GENERICO’s or NEW ALPHA’s business or the
actions required by the FDA Modernization Plan. The Parties acknowledge that the FDA Modernization Plan shall not in any event include any incremental costs included in the Melrose Park EU Plan. 
 14.3 Decommissioned Equipment. GENERICO will not de-commission, modify, move or fail to maintain any equipment or systems or revise approved
regulatory processes related to systems and equipment in the Melrose Park Facility that is operational as of the Effective Date such that the equipment or system would require re-validation in accordance with FDA regulatory requirements. For the
avoidance of doubt, in no event will GENERICO have any obligation to re-validate any equipment or system that is decommissioned as of the Effective Date. 
 14.4 Melrose Park Equipment. GENERICO will maintain the equipment and systems in the Melrose Park Facility in reasonably good working order. 
 14.5 Melrose Park Facility Conveyance/Transfer. 
 (A) Transfer of Employees at Melrose Park Facility. To the extent reasonably requested by NEW ALPHA, GENERICO shall cooperate reasonably and in good faith with NEW ALPHA with respect to the transfer of
GENERICO’s employees at the Melrose Park Facility to NEW ALPHA. If and to the extent NEW ALPHA hires any such employees, the Management Fee shall be reduced on a dollar-for-dollar basis based upon the total compensation (i.e., base
salary, bonus, medical benefits, equity incentives, etc.) paid to such employees. 
  

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 (B) Training. NEW ALPHA shall have the right to train and integrate all appropriate personnel
of GENERICO with respect to Nab technology. In connection with such training, GENERICO will not in any event be obligated to incur incremental shutdown time outside the ordinary course of its business, reduce in any material respect production
capacity available for producing Generico Products (or, without the consent of NEW ALPHA, the Product or any Pipeline Product) or otherwise impact or disrupt in any material respect GENERICO’s or NEW ALPHA’s business. 
 14.6 Contract Manufacturing and Alpha Manufacturing. 
 (A) To the extent of excess capacity at the Melrose Park Facility (in all cases after satisfying 100% of NEW ALPHA’s and GENERICO’s actual demand for the Product, Pipeline Products and Generico Products, as
applicable, GENERICO will undertake any contract manufacturing opportunities presented by NEW ALPHA subject to the following: 
 (i) GENERICO will in no event be required to contract manufacture any products that then compete with any of its products, pending products or products (it being understood that the foregoing shall not apply with respect to Pipeline
Products); 
 (ii) GENERICO will have sole discretion to decide on key terms of contract manufacturing (including but not
limited to price, liability provisions, duration, volume levels); 
 (iii) NEW ALPHA will bear all responsibility for sourcing
all such contract manufacturing opportunities; 
 (iv) GENERICO will receive the net proceeds from any contract manufacturing
performed by GENERICO; and 
 (v) GENERICO contract manufacturing shall not obligate NEW ALPHA to perform contract
manufacturing following the end of the Term, except with NEW ALPHA’s prior written consent. 
 (B) Subject to Section 14.6(A)(i)
above, GENERICO will, in good faith, consider opportunities to provide access, at dedicated times, during which NEW ALPHA employees may utilize the equipment in the Melrose Park Facility for contract manufacturing (performed by NEW ALPHA employees,
all costs of which are to be borne by NEW ALPHA), in all cases subject to the following sentence. GENERICO will not in any event be obligated to incur incremental shutdown time outside the ordinary course of its business, reduce in any material
respect production capacity available for producing Generico Products (or, without the consent of NEW ALPHA, the Product or any Pipeline Product) or otherwise impact or disrupt in any material respect GENERICO’s or NEW ALPHA’s business or
the actions required by the FDA Modernization Plan. NEW ALPHA will receive any proceeds from any contract manufacturing performed by NEW ALPHA. 
  

 27 

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 15. Miscellaneous Provisions. 
 15.1 Independent Contractors. NEW ALPHA and GENERICO are independent Parties, and nothing contained herein will be construed to create a joint venture, partnership or similar relationship. Neither Party is
authorized to, nor will it, make any statements, claims, representations, warranties or otherwise act in any way so as to incur any liability whatsoever for which the other Party may become directly, indirectly or contingently liable. 
 15.2 Assignment. The rights and obligations of the Parties under this Agreement may not be assigned or transferred in any manner, including,
without limitation, by operation of law, sale of stock or sale of assets, without the prior written approval, which shall not be unreasonably withheld, of the other Party (and any attempt to do so will be void) except that rights to payment of money
may be assigned without such approval. Despite the foregoing, in no event will NEW ALPHA be obligated to consent to an assignment of this Agreement to a Competitor. 
 15.3 Notices. Any and all notices given pursuant to this Agreement shall be in writing and shall be deemed duly given (a) on the date of delivery if delivered personally, (b) upon confirmation of
receipt if delivered by facsimile, (c) on the first business day following the date of dispatch if delivered by a recognized next-day courier service, or (d) on the date received if delivered by registered or certified mail, return receipt
requested, postage prepaid. All notices hereunder shall be delivered as set forth below, or pursuant to such other instructions as may be designated in writing by the Party to receive such notice: 
 If to NEW ALPHA to: 
 Abraxis BioScience, Inc.

 11755 Wilshire Boulevard 
 Suite 2000 
 Los Angeles, CA 90025 
 Fax: (310) 998-8553 
 Attention: Chief Executive Officer 
 with a copy to: 
 Abraxis BioScience, Inc.

 11755 Wilshire Boulevard 
 Suite 2000 
 Los Angeles, CA 90025 
 Fax: (310) 998-8553 
 Attention: General Counsel 
 If to GENERICO to: 
 APP Pharmaceuticals,
Inc. 
 1501 East Woodfield Road, Suite 300E 
 Schaumburg, Illinois 60173 
 Fax: (847) 413-2652 
 Attention: Chief Executive Officer 
  

 28 

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 with a copy to: 
 APP Pharmaceuticals, Inc. 
 1501 East Woodfield Road, Suite 300E 
 Schaumburg, Illinois 60173 
 Fax:
(847) 413-2652 
 Attention: General Counsel 
 15.4 Force Majeure. 
 (A) The obligations of a Party hereunder will be suspended during the time and
to the extent that such Party is prevented from complying therewith due to any event or circumstances beyond the reasonable control and without the fault or negligence of the affected Party (which circumstance is hereinafter referred to as
“Force Majeure”), including but not limited to floods, fire, storms, earthquakes, lockouts, explosion, hostilities, war (whether declared or undeclared), acts of terrorism, civil disturbances, order or acts of any government,
whether de jure or de facto or any official purporting to act under authority of any such government (other than as to Regulatory Approval), illegality arising from domestic or foreign laws or regulations, insurrections, quarantine or custom
restrictions (other than due to the action or inaction of the Party claiming a Force Majeure), acts of God or other similar events beyond the reasonable control of, as the case may be, NEW ALPHA or GENERICO which results in hindrance of the
performance by the Party of its obligations hereunder. 
 (B) As soon as possible after being affected by a Force Majeure circumstance, the
affected Party must furnish to the other Party all particulars of the Force Majeure and the manner in which its performance is thereby prevented or delayed. The Party whose obligations hereunder have been suspended will promptly and diligently
pursue appropriate action to enable it to lift the Force Majeure situation, except that Party shall not be obligated to settle any strike, lockout or other labor difficulty on terms contrary to its wishes. 
 15.5 Amendment and Waiver. This Agreement (including the Exhibits hereto) may be amended, modified, superseded or cancelled, and any other of the
terms or conditions hereof may be modified, only by a written instrument executed by both Parties or, in the case of a waiver, by the Party waiving compliance. Failure of either Party at any time or times to require performance of any provision
hereof will in no manner affect the right of such Party at a later time to enforce the same, and no waiver of any nature, whether by conduct or otherwise, in any one or more instances, will be deemed to be or considered as a further or continuing
waiver of any provision of this Agreement. 
 15.6 Severability. If any one or more of the agreements, provisions or terms contained
herein are declared invalid, illegal or unenforceable in any respect, the validity of the remaining agreements, provisions or terms contained will shall in no way be affected, prejudiced or invalidated thereby. 
  

 29 

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 15.7 Entire Agreement. This Agreement, together with the Exhibits hereto and the
Specifications, contains the entire agreement between the Parties, and supersedes any agreements between them with respect to the subject matter hereof. 
 15.8 Section Headings; Recitals. The section headings contained in this Agreement are for reference purposes only and will not affect in any way the meaning or interpretation of this Agreement. The recitals are
hereby incorporated into this Agreement by reference. 
 15.9 Governing Law. This Agreement shall be governed by and construed and
enforced in accordance with the substantive law (without regard to conflicts of law provisions) of the State of Delaware. 
 15.10 Consent
to Jurisdiction. Each of GENERICO and NEW ALPHA irrevocably agrees that any legal action or proceeding with respect to this Agreement, the transactions contemplated hereby, any provision hereof, the breach, performance, validity or invalidity
hereof or for recognition and enforcement of any judgment in respect hereof brought by another Party or its successors or permitted assigns shall be brought and determined in any federal or state court located in the State of Delaware, and each of
GENERICO and NEW ALPHA hereby irrevocably submits with regard to any such action or proceeding for themselves and in respect to their property, generally and unconditionally, to the exclusive jurisdiction of the aforesaid courts. Each of GENERICO
and NEW ALPHA hereby irrevocably waives, and agrees not to assert, by way of motion, as a defense, counterclaim or otherwise, in any action or proceeding with respect to this Agreement, the transactions contemplated hereby, any provision hereof or
the breach, performance, enforcement, validity or invalidity hereof, (A) any claim that it is not personally subject to the jurisdiction of the above-named courts for any reason other than the failure to lawfully serve process, (B) that it
or its property is exempt or immune from jurisdiction of any such court or from any legal process commenced in such courts (whether through service of notice, attachment prior to judgment, attachment in aid of execution of judgment, execution of
judgment or otherwise) and (C) to the fullest extent permitted by applicable laws, that (i) the suit, action or proceeding in any such court is brought in an inconvenient forum, (ii) the venue of such suit, action or proceeding is
improper and (iii) this Agreement, or the subject matter hereof, may not be enforced in or by such courts. 
 15.11 No Strict
Construction. The language used in this Agreement will be deemed to be the language chosen by the Parties hereto to express their mutual intent, and no rule of strict construction will apply to any term or condition of this Agreement.

 15.12 Survival. Except to the extent that any monies are owed and not yet paid and for the provisions of Sections 1, 2.2(H),
2.2(I), 2.5, 3.2(C), 3.5, 5.1 (last sentence), 5.2 (last sentence), 5.3 (last sentence), 6, 8, 9, 10, 11, 12 and 15, none of the provisions herein shall survive termination or expiration of this Agreement. Sections 2.2(H), 2.5, 3.2(C) and 3.5 shall
survive until the seventh anniversary of the termination or expiration of this Agreement. 
 15.13 Counterparts. This Agreement may be
executed in separate counterparts, each of which will be deemed to be an original, but which together will constitute one and the same instrument. An executed signature page of this Agreement delivered by facsimile transmission shall be effective as
an original executed signature page. 
  

 30 

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 15.14 Enforcement. The Parties agree that irreparable damage would occur in the event that any
of the provisions of this Agreement were not performed by the Parties in accordance with their specific terms. It is accordingly agreed that the Parties shall be entitled to specific performance of the terms hereof, this being in addition to any
other remedy to which a Party is entitled at law or in equity. 
 [REMAINDER OF PAGE LEFT INTENTIONALLY BLANK] 
  

 31 

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 IN WITNESS WHEREOF, the Parties hereto have executed this Manufacturing Agreement as of the date and
year first written above. 
  

			
	NEW ABRAXIS, INC.
		
	By:	 	  

	Name:	 	  

	Title:	 	  

	
	APP PHARMACEUTICALS LLC
		
	By:	 	  

	Name:	 	  

	Title:	 	  

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 EXHIBIT A 
 DESCRIPTION OF PRODUCT, OR PIPELINE PRODUCTS, PROCESSING 
 (***). 

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 EXHIBIT B 
 NEW ALPHA INSURANCE 
 $25,000,000 PER INCIDENT AND
IN THE AGGREGATE 

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 EXHIBIT C 
 GENERICO INSURANCE 
 $25,000,000 PER INCIDENT AND
IN THE AGGREGATE 

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 SCHEDULE 1.4 
 PART A 
 2008 ANNUAL FORECAST 
 Melrose Park 
  

			
		
	 GENERICO Lyophilizer Cycles:
	  	(***)
		
	 NEW ALPHA Lyophilizer Cycles:
	  	(***)
		
	 Units (in millions)
	  	
		
	 GENERICO Lyophilizer-produced Units
	  	(***)
		
	 NEW ALPHA Lyophilizer-produced Units
	  	(***)

 Grand Island 
  

			
		
	 GENERICO Lyophilizer Cycles:
	  	(***)
		
	 NEW ALPHA Lyophilizer Cycles:
	  	(***)
		
	 Units (in millions)
	  	
		
	 GENERICO Lyophilizer-produced Units
	  	(***)
		
	 NEW ALPHA Lyophilizer-produced Units
	  	(***)

 PART B 
 2009, 2010, 2011 AND 2012 ESTIMATES 
 Melrose Park 
  

									
					
	 	  	2009	 	2010	 	2011	 	2012
					
	 GENERICO Lyophilizer Cycles:
	  	(***)	 	(***)	 	(***)	 	(***)
					
	 NEW ALPHA Lyophilizer Cycles:
	  	(***)	 	(***)	 	(***)	 	(***)
					
	 Units (in millions)
	  		 		 		 	
					
	 GENERICO Lyophilizer-produced Units
	  	(***)	 	(***)	 	(***)	 	(***)
					
	 NEW ALPHA Lyophilizer-produced Units
	  	(***)	 	(***)	 	(***)	 	(***)

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 Grand Island 
  

									
					
	 	  	2009	 	2010	 	2011	 	2012
					
	 GENERICO Lyophilizer Cycles:
	  	(***)	 	(***)	 	(***)	 	(***)
					
	 NEW ALPHA Lyophilizer Cycles:
	  	(***)	 	(***)	 	(***)	 	(***)
					
	 Units (in millions)
	  		 		 		 	
					
	 GENERICO Lyophilizer-produced Units
	  	(***)	 	(***)	 	(***)	 	(***)
					
	 NEW ALPHA Lyophilizer-produced Units
	  	(***)	 	(***)	 	(***)	 	(***)

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 SCHEDULE 1.66 
 TERRITORIES 
  

	 	•	 	 European Economic Area 

  

	 	•	 	 (***) 

  

	 	•	 	 Australia 

  

	 	•	 	 Japan 

  

	 	•	 	 China (including Hong Kong and Macau) 

  

	 	•	 	 India 

  

	 	•	 	 Republic of Korea 

  

	 	•	 	 (***) 

  

	 	•	 	 (***) 

  

	 	•	 	 (***) 

  

	 	•	 	 (***) 

  

	 	•	 	 (***) 

  

	 	•	 	 (***) 

  

	 	•	 	 (***) 

  

	 	•	 	 (***) 

  

	 	•	 	 (***) 

  

	 	•	 	 (***) 

  

	 	•	 	 Gulf States (including Saudi Arabia, United Arab Emirates, Kuwait, Oman and Dubai) 

  

	 	•	 	 (***) 

  

	 	•	 	 (***) 

  

	 	•	 	 (***) 

  

	 	•	 	 (***) 

  

	 	•	 	 (***) 

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 SCHEDULE 2.10 
 OTHER SERVICES 
  

					
	 Service
	  	Charges1	 	Assumptions
	Manufacturing-Related Information Technology Support	  	(***)	 	(***)
			
	 Corporate QA, including;
  
 •     establishment of quality systems and regulatory oversight;
  
 •     review of suppliers to
ensure quality systems requirements are met;
  
 •     review of internal functions to ensure quality systems requirements are met;
  
 •     provide polices, SOPs & protocols support to all functions;
  
 •     provide warehousing
support to ensure materials have been received, sampled and shipped according to requirements;
  
 •     review of product development reports;
  
 •     calibration, maintenance
and preventive maintenance of analytical equipment; and
  
 •     QA, validation and change control of multi-site computer systems.
	  	(***)	 	(***)

	 1
	 Charges shall be increased each year by (***). Actual charges will be based upon
time and materials. 

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

					
	 Service
	  	Charges1	 	Assumptions
	 Corporate QC, including;
  
 •     analytical testing of raw materials and components; and
  
 •     validation of analytical
equipment and software systems.
	  	(***)	 	(***)
			
	 CGMP and other plant-related training
	  	(***)	 	(***)

 Note: Redacted portions have been marked with (***). The redacted portions are subject to a request for
confidential treatment that has been filed with the Securities and Exchange Commission. 
  

 SCHEDULE 4.1 
 UNIT COST FOR ABRAXANE2 
  

	1.	(***) for units manufactured at 2020 Ruby Street, Melrose Park, Illinois. 

  

	2.	(***) for units manufactured at 3159 Staley Road, Grand Island, New York. 

 BATCH COST FOR ANY PIPELINE PRODUCT 
  

	 	•	Actual cost for Generico Manufacturing, plus (***). The actual cost for Generico Manufacturing of Pipeline Products shall be verified and approved by NEW ALPHA prior to their
production. 

  

	 2
	 Charges shall be increased each year by (***).

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