Document:

<PAGE>
                                                                    EXHIBIT 10.4

                                OPTION AGREEMENT
                                ----------------

     This Option Agreement (the "Agreement") is dated as of the _____ day of
October, 2001, by and among Heather U. Baines and Lloyd McAdams, as Trustees of
The Heather U. Baines and Lloyd McAdams Living Trust dated August 10, 2001 (the
"Stockholder"), Anworth Mortgage Asset Corporation, a Maryland corporation (the
"Company"), and Anworth Mortgage Advisory Corporation, a California corporation
(the "Manager").

                                R E C I T A L S :
                                - - - - - - - -

     A.   The Stockholder owns all of the issued and outstanding shares of
common stock, $.01 par value (the "Common Stock"), of the Manager.

     B.   Effective March 17, 1998, the Company and the Manager entered into
that certain Management Agreement, pursuant to which the Manager performs
services for the Company upon the terms and in consideration of the fees set
forth therein (the "Management Agreement").

     C.   The Stockholder desires to grant the option set forth herein (the
"Option") to permit the Company, if and when such Option is exercised, to
purchase the Common Stock pursuant to a merger of the Manager with and into the
Company (the "Merger").

                               A G R E E M E N T :
                               - - - - - - - - -

     NOW, THEREFORE, for good and valuable consideration, the receipt and
sufficiency of which is hereby acknowledged, and in consideration of the
promises and the undertakings of the parties hereto hereinafter contained, it is
hereby agreed:

     1.   Grant of Option; Anti-Dilution of Consideration.
          -----------------------------------------------

          a.   Subject to the terms and conditions set forth herein, including,
without limitation, those set forth in Section 3 hereof, the Stockholder hereby
grants to the Company the Option to purchase all, but not part, of the Common
Stock, for aggregate consideration consisting of Two Hundred Forty Thousand
(240,000) shares of the common stock, $.01 par value per share, of the Company
(the "Consideration").

          b.   If the number of issued and outstanding shares of the Company's
common stock changes by reason of any stock dividend, stock split, reverse stock
split, recapitalization, combination, merger or other change in the corporate or
capital structure of the Company, the number of shares of the Company's common
stock constituting the Consideration shall be appropriately adjusted so that
upon exercise of the Option the Stockholder shall receive the number and class
of shares or other securities or property that the Stockholder would have
received in respect of the Consideration if the Option had been exercised
immediately prior to such event.

<PAGE>

     2.   Term of Option. The Option shall expire at 5:00 P.M., Pacific Time, on
          --------------
April 30, 2003, unless such Option shall theretofore have been terminated in
accordance with the provisions hereinafter set forth (the "Termination Date").
Such termination shall not affect the parties' ability to consummate the Merger
if the Option is properly exercised on or prior to the Termination Date.

     3.   Company's Conditions to Exercise and Merger. The exercise of the
          -------------------------------------------
Option and consummation of the Merger are subject to the following conditions
precedent having been fulfilled or waived in writing by the Company (except with
respect to Section 3.a., which must be fulfilled as a condition to the exercise
of the Option, and Section 3.b.(ii), which must be fulfilled as a condition to
the Merger):

          a.   With respect to the exercise of the Option, the following
condition shall apply: The independent members of the Board of the Company (the
"Board") shall have made a determination that the Merger would be in the best
interests of the Company's stockholders in light of all relevant circumstances,
including, without limitation, the fulfillment of each of the Stockholder's
conditions to the exercise of the Option set forth in Section 4 hereof; and

          b.   With respect to the consummation of the Merger, the following
conditions shall apply:

               (i)  the Board shall have received a fairness opinion from a
reputable investment banking firm regarding the fairness of the Merger
consideration prior to consummation of the Merger; and

               (ii) the Merger shall have been approved by the stockholders of
the Company and the Stockholder shall agree to vote its shares of Company in
favor of the Merger.

     4.   Stockholder's Conditions to Exercise. The exercise of the Option is
          ------------------------------------
subject to the following conditions precedent having been fulfilled or waived by
the Stockholder in writing and the Option shall not be exercisable by the
Company until such time:

          a.   The Company shall have entered into a reasonable and acceptable
employment agreement with McAdams and each of the other key members of the
Company's management team as designated by McAdams. McAdams employment agreement
shall be similar in form to those of similarly situated Chief Executive Officers
of other mortgage real estate investment trusts, which shall include, without
limitation (i) appointment of McAdams as the Company's President and Chief
Executive Officer of the Company, (ii) participation by McAdams in the Company's
Incentive Compensation Plan (as defined below), (ii) a three (3) year term
renewing automatically each year for additional one (1) year terms, unless
terminated by either of the parties thereto on not less than six (6) months
prior written notice, and (iii) severance provisions equal to not less than
three (3) years base salary, projected participation in the Company's Incentive
Compensation Plan for such period, full payment of benefits for such period and
full vesting of all options to purchase Company common stock and of all Company
common stock paid to McAdams under the Incentive Compensation Plan, in the event
McAdams is terminated without "cause" or terminates for "good reason"
(including, without limitation, upon a change in control or similar event of the
Company). The employment agreements for the

                                       -2-

<PAGE>

other key members of the management team designated by McAdams shall be similar
in form to those of similarly situated key executives of other mortgage real
estate investment trusts and shall be negotiated in good faith by the Board
following recommendations from McAdams.

          b.   The Company shall have adopted an incentive compensation plan
(the "Incentive Compensation Plan") pursuant to which the key executives of the
Company designated by McAdams shall be entitled to earn incentive compensation
calculated as set forth on Exhibit A attached hereto (the "Incentive
Compensation"). The incentive compensation would be allocated annually by the
Board (following the recommendations of McAdams) and the Incentive Compensation
Plan would permit participants to receive fifty percent (50%) of all amounts
earned in Incentive Compensation in excess of $50,000 per annum in Company
common stock, which stock shall be subject to vesting as reasonably determined
by the Board.

          c.   The Board shall have increased the size of the Company's 1997
Stock Option and Awards Plan, as amended (the "Plan"), so that the number of
shares authorized for grant thereunder shall not at any time equal less than
fifteen percent (15%) of the total number of issued and outstanding shares of
the capital stock of the Company and the Board shall be entitled to grant stock
options and other awards thereunder in its discretion. Nothing herein shall be
construed in any way to require the exercise of the Option as a condition to an
increase in the number of shares authorized under the Plan, or any other
amendment thereto, which increase or amendment shall be subject solely to
approval of the Board and the Company's stockholders as required by law

     5.   Manner of Exercise of Option. This Option may be exercised by written
          ----------------------------
notice delivered to the Stockholder stating that the Option is being exercised
with respect to all, but not part, of the Common Stock. Thereafter, the Merger
shall be consummated on the earliest practicable date following the fulfillment
or appropriate waiver of each of the conditions set forth in Section 3 and 4
above and negotiation and execution of a mutually reasonably agreed upon merger
agreement between the parties.

     6.   Management Agreement. Upon the consummation of the Merger, the parties
          --------------------
agree that the Management Agreement shall terminate and be of no further force
or effect and no termination fee shall be payable thereunder.

     7.   Successors and Assigns. This Agreement shall be binding upon and inure
          ----------------------
to the benefit of the parties hereto and their respective successors and
assigns. This Agreement shall not be assignable by either party without the
prior written consent of the other party.

     8.   Notices. All notices, requests, demands and other communications
          -------
hereunder shall be in writing and shall be deemed to have been duly given if (i)
telefaxed to the telefax numbers of the other parties as listed below, or (ii)
delivered or mailed by registered or certified mail to the addresses hereinafter
described or at such other addresses as may be designated in writing by notice
given by registered or certified mail to the other party. The date of the giving
of such notices, requests, demands, and other communications shall be deemed to
be three (3) days after the date of the posting of the mail, if mailed, or the
date of delivery, if delivered other than by mail.

                                       -3-

<PAGE>

If to the Stockholder:

     1299 Ocean Avenue, Suite 200
     Santa Monica, California 90401
     Telefax:  (310) 434-0100

If to the Company:

     1299 Ocean Avenue, Suite 200
     Santa Monica, California 90401
     Attention: President
     Telefax: (310) 434-0100

With a copy to:

     Allen Matkins Leck Gamble & Mallory LLP
     1901 Avenue of the Stars, 18th Floor
     Los Angeles, California 90067
     Attention: Mark J. Kelson, Esq.
     Telefax: (310) 788-2410

     9.   Governing Law. The Agreement shall be construed and interpreted in
          -------------
accordance with the laws of the State of California for contracts made and
performed entirely in the State of California.

     10.  Headings. The captions and other headings contained in this Agreement
          --------
are for convenience only and shall not be considered a part of or affect the
construction and interpretation of any provision of this Agreement.

     11.  Counterparts. This Agreement may be executed in one or more
          ------------
counterparts, all of which shall be deemed an original, but all of such shall
constitute one and the same Agreement.

     12.  Amendments and Waivers. This Agreement may be amended or any provision
          ----------------------
of this Agreement waived only the written consent of the Stockholder and the
Company. The rights or remedies of the Stockholder and the Company under this
Agreement shall be cumulative and not exclusive of any rights or remedies that
the Stockholder or the Company would otherwise have and no course of dealing
between the Stockholder and the Company nor any failure or delay by the
Stockholder or the Company in exercising any right shall operate as a waiver of
such right nor shall any single or partial exercise of any power or right
preclude its other or further exercise or the exercise of any other power or
right.

     13.  Severability. Any provision of this Agreement which is prohibited or
          ------------
unenforceable in any jurisdiction shall be ineffective to the extent of such
prohibition or unenforceability without affecting, impairing or invalidating the
remaining provisions hereof or

                                       -4-

<PAGE>

the enforceability thereof in such jurisdiction or the validity or
enforceability of any provision hereof in any other jurisdiction.

     14.  Entire Agreement. This Agreement constitutes the entire agreement and
          ----------------
understanding of the parties with respect to the subject matter hereof and
supersedes all prior agreements, arrangement, and understandings among the
parties with respect to the subject matter hereof. No representation, promise,
inducement, statement or intention has been made by any party hereto that is not
embodied herein, and no party shall be bound by or liable for any alleged
representation, promise, inducement or statement not so set forth herein.

     15.  Further Assurances. From and after the date of this Agreement, upon
          ------------------
the reasonable request of either party, the other party shall execute and
deliver such instruments, documents and other writings as may be reasonably
necessary or desirable to confirm and carry out the intent and purposes of this
Agreement and the transactions contemplated hereby.

     16.  Attorneys' Fees. In the event of any controversy, claim or dispute
          ---------------
among the parties hereto arising out of or relating to this Agreement, or any
breach hereof, the prevailing party shall be entitled to recover from the losing
party reasonable attorney's fees, expenses and costs.

                                       -5-

<PAGE>

     IN WITNESS WHEREOF, the parties have duly executed this Agreement as of the
date first above written.

"STOCKHOLDER"                           "COMPANY"

THE HEATHER U. BAINES AND LLOYD         ANWORTH MORTGAGE ASSET CORPORATION
MCADAMS LIVING TRUST

By:                                     By:
    ---------------------------             ------------------------------
Lloyd McAdams                           Name:
Co-Trustee                                    ----------------------------
                                        Title:
                                               ---------------------------

By:
    ---------------------------
Heather U. Baines
Co-Trustee

"MANAGER"

ANWORTH MORTGAGE ADVISORY
CORPORATION (with respect to Section 6 of
this Agreement)

By:
    ---------------------------
Name:
      -------------------------
Title:
       ------------------------

                                       -6-

<PAGE>

                                    EXHIBIT A

                      CALCULATION OF INCENTIVE COMPENSATION

     Incentive Compensation to be paid under the Incentive Compensation Plan (as
defined in the Agreement of which this Exhibit A is made a part) for each fiscal
quarter shall be an amount equal to the Applicable Percentage (as set forth on
the table below) of the Net Income of the Company, before incentive
compensation, for such fiscal quarter in excess of the amount that would produce
an annualized Return on Equity (calculated by multiplying the Return on Equity
for such fiscal quarter by four) equal to the Ten-Year U.S. Treasury Rate for
such fiscal quarter plus 1% (the "Incentive Compensation"). The Incentive
Compensation calculation and payment shall be made quarterly in arrears. The
Company shall compute the quarterly Incentive Compensation within 45 days after
the end of such fiscal quarter, at which time the Company shall deliver a
written statement to each participant under the Incentive Compensation Plan (the
"Participants") setting forth the computation of the Incentive Compensation for
such quarter. The Company shall pay the Incentive Compensation with respect to
each fiscal quarter within 15 days following delivery of such computation by the
Company to the Participants. In connection with the Company's annual audit, the
Company shall compute any final adjustments to the Incentive Compensation
payable within 45 days after the end of each fiscal year, at which time the
Company shall deliver such computation to the Participants. Any required
adjustments shall be paid by the Company within 15 days after delivery of such
computation by the Company to the Participants and any amounts payable by the
Participants shall be deducted from the next succeeding payment(s) of Incentive
Compensation under the Incentive Compensation Plan.

---------------------------------     -------------------------------------
       Average Net Worth                      Applicable Percentage
       -----------------                      ---------------------
---------------------------------     -------------------------------------
       First $50 million                               25%
---------------------------------     -------------------------------------
---------------------------------     -------------------------------------
        Next $50 million                               20%
---------------------------------     -------------------------------------
---------------------------------     -------------------------------------
       Next $100 million                               10%
---------------------------------     -------------------------------------
---------------------------------     -------------------------------------
         All thereafter                                5%
---------------------------------     -------------------------------------

     As used herein, the following terms shall have the meanings set forth
below:

     "Average Net Worth" means for any period (i) the daily average of the
cumulative net proceeds to date from all offerings of the Company's equity
securities, after deducting any underwriting discounts and commissions and other
expenses and costs relating to the offerings, plus (ii) the Company's retained
earnings (without taking into account any losses incurred in prior periods)
computed by taking the average of such values at the end of each month during
such period.

"Net Income" shall mean the taxable income of the Company (including net capital
gains, if any) before incentive compensation, net operating loss deductions
arising from losses in prior periods and deductions permitted by the United
States Internal Revenue Code in calculating taxable income for a real estate
investment trust plus the effects of adjustments, if any, necessary to record
hedging and interest transactions in accordance with generally accepted
accounting principles consistently applied. A deduction of all of the Company's
interest expenses for borrowed funds is taken into account in calculating Net
Income.

"Return on Equity" means an amount calculated for any quarter by dividing the
Company's Net Income for the year by the Company's Average Net Worth for the
quarter.<PAGE>

                                                                    EXHIBIT 10.1

                                       COR
                             COR Therapeutics, Inc.
--------------------------------------------------------------------------------

                           1991 Equity Incentive Plan
                             Stock Option Agreement

     COR Therapeutics, Inc. (the "Company"), pursuant to its 1991 Equity
Incentive Plan (the "Plan"), has granted to you, the optionee named on page 1 of
this Notice of Grant of Stock Options and Option Agreement, an option to
purchase shares of the common stock of the Company ("Common Stock"). This option
may be intended to qualify as an "incentive stock option" within the meaning of
Section 422 of the Internal Revenue Code of 1986, as amended (the "Code").

     The grant hereunder is in connection with and in furtherance of the
Company's compensatory benefit plan for participation of the Company's
employees, directors, and consultants. Defined terms not explicitly defined in
this agreement but defined in the Plan shall have the same definitions as in the
Plan.

     The details of your option are as follows:

1.   The total number of shares of Common Stock subject to this option is
indicated on page 1 of this Notice of Grant of Stock Options and Option
Agreement. Subject to the limitation contained herein, this option shall be
exercisable on or after the date of vesting applicable to each installment as
shown on the vesting schedule on page 1 of this Notice of Grant of Stock Options
and Option Agreement.

2.   (a) The exercise price of this option is indicated on page 1 of this Notice
         of Grant of Stock Options and Option Agreement and is not less than the
         fair market value of the Common Stock on the date of grant of this
         option.

     (b) Payment of the exercise price is due in full upon exercise of all or
         any part of each installment which has accrued to you. You may elect,
         to the extent permitted by applicable statutes and regulations, to make
         payment of the exercise price under one of the following alternatives:
          (i)   Payment in cash (including check) at the time of exercise;
          (ii)  Payment pursuant to a program developed under Regulation T as
                promulgated by the Federal Reserve Board which, prior to the
                issuance of Common Stock, results in either the receipt of cash
                (or check) by the Company or receipt of irrevocable instructions
                to pay the aggregate exercise price to the Company from the sale
                proceeds;
          (iii) Provided that at the time of exercise the Company's Common Stock
                is publicly traded and quoted regularly in The Wall Street
                Journal, payment by delivery of already-owned shares of Common
                Stock, held for the period required to avoid a charge to the
                Company's reported earnings, and owned free and clear of any
                liens, claims, encumbrances, or security interests, which Common
                Stock shall be valued at its fair market value on the date of
                exercise; or
          (iv)  Payment by a combination of the above methods.

3.   The minimum number of shares with respect to which this option may be
exercised at any one time is one hundred (100) shares, except (a) as to an
installment subject to exercise, as set forth in paragraph 1 above, which
amounts to fewer than one hundred (100) shares, in which case, as to the
exercise of that installment, the number of shares in such installment shall be
the minimum number of shares, and (b) with respect to the final exercise of this
option, this minimum shall not apply. In no event may this option be exercised
for any number of shares which would require the issuance of anything other than
whole shares.

4.   Notwithstanding anything to the contrary contained herein, this option may
not be exercised unless the shares issuable upon exercise of this option are
then registered under the Securities Act of 1993, as amended (the "Securities
Act") or, if such shares are not then so registered, the Company has determined
that such exercise and issuance would be exempt from the registration
requirements of the Securities Act and the registration or qualification
requirements of applicable state securities laws.

5.   The term of this option commences on the date of grant as indicated on page
1 of this Notice of Grant of Stock Options and Option Agreement and expires at
close of business on the "Expiration Date," which is the day before the tenth
anniversary of the date of grant, unless this option expires sooner as set forth
below or in the Plan. In no event may this

<PAGE>

option be exercised after the Expiration Date. This option shall terminate prior
to the Expiration Date on the date which is three (3) months after the
termination of your employment with or service as a consultant to the Company or
an Affiliate for any reason or no reason unless:
     (a) Your termination of employment or consulting relationship is due to
         your permanent and total disability (within the meaning of Section
         422(c)(6) of the Code), in which event this option will expire on the
         earlier of the Expiration Date set forth above or one (1) year
         following such termination of employment or consulting relationship; or
     (b) Your termination of employment or consulting relationship is due to
         your death, in which event this option will expire on the earlier of
         the Expiration Date set forth above or eighteen (18) months after your
         death; or
     (c) During any part of such three (3) month period the option is not
         exercisable solely because of the condition set forth in paragraph 4
         above, in which event this option will not expire until the earlier of
         the Expiration Date set forth above or until it shall have been
         exercisable for an aggregate period of three (3) months after your
         termination of employment or consulting relationship; or
     (d) Exercise of this option within the three (3) months after termination
         of your employment or consulting relationship would result in liability
         under Section 16(b) of the Securities Exchange Act of 1934, as amended,
         in which event this option will expire on the earlier of (i) the
         Expiration Date set forth above, (ii) the tenth (10th) day after the
         last date upon which exercise would result in such liability, or (iii)
         six (6) months and ten (10) days after the termination of your
         employment with or service as a consultant to the Company or an
         Affiliate.

     However, this option may be exercised following termination of your
employment or consulting relationship only as to that number of shares as to
which it was exercisable on the date of termination of your employment or
consulting relationship under the provisions of paragraph 1 of this option.

6.   (a) This option may be exercised, to the extent specified above, by
         delivering a notice of exercise (in a form designated by the Company)
         together with the exercise price to the Secretary of the Company, or to
         such other person as the Company may designate, during regular business
         hours, together with such additional documents as the Company may then
         require pursuant to the Plan.

     (b) By exercising this option you agree that, as a precondition to the
         completion of any exercise of this option:
          (i)   the Company may require you to enter into an arrangement
                providing for the payment by you to the Company of any tax
                withholding obligation of the Company arising by reason of (1)
                the exercise of this option, (2) the lapse of any substantial
                risk of forfeiture to which the shares are subject at the time
                of exercise, or (3) the disposition of shares acquired upon such
                exercise; and
          (ii)  you will notify the Company in writing within fifteen (15) days
                after the date of any disposition of any of the shares of the
                Common Stock issued upon exercise of this option that occurs
                within two (2) years after the date of grant of this option or
                within one (1) year after such shares of Common Stock are
                transferred upon exercise of this option.

7.   This option is not transferable, except by will or by the laws of descent
and distribution or pursuant to a domestic relations order, and is exercisable
during your life only by you. Notwithstanding the foregoing, by delivering
written notice to the Company, in a form satisfactory to the Company, you may
designate a third party who, in the event of your death, shall thereafter be
entitled to exercise this option.

8.   This option is not an employment contract and nothing in this option shall
be deemed to create in any way whatsoever any obligation on your part to
continue in the employ of the Company or an Affiliate, or of the Company or an
Affiliate to continue your employment. In addition, nothing in this option shall
obligate the Company or any Affiliate, or their respective directors, officers,
or employees, to continue any relationship which you might have as a consultant
to the Company or an Affiliate.

9.   Any notices provided for in this option or the Plan shall be given in
writing and shall be deemed effectively given upon receipt or, in the case of
notices delivered by the Company to you, five (5) days after deposit in the
United States mail, postage prepaid, addressed to you at the address specified
in the Company records or at such other address as you hereafter designate by
written notice to the Company.

10.  This option is subject to all the provisions of the Plan, a copy of which
is available upon request, and its provisions are hereby made a part of this
option, including, without limitation, the provisions of paragraph 5 of the Plan
relating to option provisions, and is further subject to all interpretations,
amendments, rules, and regulations which may from time to time be promulgated
and adopted pursuant to the Plan. In the event of any conflict between the
provisions of this option and those of the Plan, the provisions of the Plan
shall control.

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