Document:

Fourth Amended and Restated Members Agreement

 Exhibit 10.8 
 SAGENT HOLDING CO. 
 FOURTH AMENDED AND RESTATED MEMBERS AGREEMENT

 This Fourth Amended and Restated Members Agreement (the “Agreement”) is made and entered into as of
September 3, 2010 by and among Sagent Holding Co., a Cayman Islands exempted company (the “Company”), each of the members listed on Exhibit A attached hereto (collectively, the “Existing Investors”) and
each of the members listed on Exhibit B attached hereto (collectively, the “New Investors,” and together with the Existing Investors, the “Investors”). 

RECITALS 

A. The Existing Investors currently own Ordinary Shares (the “Ordinary Shares”), Series A Preference Shares (the
“Series A Shares”), Series B Preference Shares (the “Series B Shares”) and/or Series B-1 Preference Shares (the “Series B-1 Shares”) of the Company. 

B. The Company and the Existing Investors are parties to that certain Third Amended and Restated Members Agreement dated as of
April 6, 2010 (the “Prior Agreement”). 
 C. The Company is issuing to the New Investors additional Series
B-1 Preference Shares of the Company (the “Series B-1 Shares”) pursuant to the Series B-1 Preference Shares Purchase Agreement dated as of September 3, 2010 (as may be amended from time to time, the “B-1 Extension Purchase
Agreement”). 
 D. It is a condition to the closing of the sale of the additional Series B-1 Shares to the New
Investors pursuant to the B-1 Extension Purchase Agreement that the Company and the Investors enter into this Agreement. 
 E.
The Company and the Existing Investors desire to amend and restate the Prior Agreement in its entirety as set forth herein and to accept the rights and obligations created pursuant hereto in lieu of their rights and obligations under the Prior
Agreement. 
 AGREEMENT 
 NOW, THEREFORE, in consideration of the foregoing premises and certain other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Parties (each, a
“Party” and collectively, the “Parties”) agree as follows: 
  

	 	1.	Certain Definitions. 

 As used in this Agreement, the following terms shall have the following respective meanings: 
 (a) “Articles” shall mean the Sixth Amended and Restated Articles of Association of the Company, as amended from time to time in accordance with its terms. 

(b) “Board” shall mean the board of directors of the Company. 

 (c) “Commission” shall mean the United States Securities and
Exchange Commission or any other federal agency at the time administering the Securities Act. 
 (d) “Conversion
Shares” shall mean the Ordinary Shares issued or issuable pursuant to conversion of the Preference Shares. 
 (e)
“Deemed Liquidation Event” has the meaning set forth in the Articles. 
 (f) “ERISA
Investor” shall mean an Investor whom (i) (A) is a “benefit plan investor” (as such term is defined in the regulations of the U.S. Department of Labor included within 29 C.F.R. section 2510.3-101) subject to the
fiduciary responsibility provisions of part 4 of title I of the U.S. Employee Retirement Income Security Act of 1974, as amended from time to time (“ERISA”) and (B) so indicates in writing to the Company on or before the date of this
Agreement and is so identified on the Company’s register of members or (ii) is otherwise determined by the Company or the Board to be an ERISA Partner within the meaning of subsection (i) of this definition. 

(g) “Exchange Act” shall mean the Securities Exchange Act of 1934, as amended. 

(h) “Holder” shall mean (i) any Investor and (ii) any person holding Registrable Securities to whom the
rights under Section 2 have been transferred in accordance with Section 2.13. 
 (i) “Initiating
Holders” shall mean any Holders who in the aggregate hold at least 50% of the Registrable Securities then outstanding. 

(j) “Investor” shall mean any person or entity listed on Exhibit A and/or Exhibit B hereto or a
permitted assignee or transferee thereof in accordance with the terms of this Agreement. 
 (k) “IPO”
shall mean the closing of the Company’s first firm commitment underwritten public offering pursuant to an effective registration statement under the Securities Act or similar securities laws, to the extent applicable, in connection with an
offering of securities in another jurisdiction with an internationally recognized securities market. 
 (l)
“Memorandum” shall mean the Sixth Amended and Restated Memorandum of Association of the Company. 
 (m)
“Ordinary Shares” shall mean ordinary shares of the Company. 
 (n) “Original Issue
Price” has the meaning set forth in the Articles. 
 (o) “Preference Shares” shall mean the
Series A Shares, Series B Shares and Series B-1 Shares. 
 (p) “Qualified IPO” shall mean an IPO with
gross cash proceeds to the Company of not less than US$85,000,000.00 and a per share offering price of at least US$4.00 (as adjusted for Recapitalizations and prior to underwriting commission and expense) and a pre-offering valuation of the Company
of at least US$450,000,000 (calculated as the offering price to the public multiplied by the number of Ordinary Shares outstanding immediately following the offering, on a fully diluted basis) and in connection with which the Company has satisfied
the listing requirements of an internationally recognized stock exchange or quotation system. 

  
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 (q) “Recapitalization” means any share split, share dividend, share
combination or consolidation or other recapitalization in relation to the shares of the Company. 
 (r)
“Registrable Securities” shall mean (i) issued or issuable Conversion Shares, (ii) Ordinary Shares held by the Investors (other than shares acquired in market transactions), and (iii) any Ordinary Shares of the
Company issued or issuable in respect of the Conversion Shares upon Recapitalization and any Ordinary Shares otherwise issuable with respect to such shares referenced in (i) or (ii) above; provided, however, that Ordinary
Shares or other securities shall only be treated as Registrable Securities if and so long as they have not been sold to or through a broker or dealer or underwriter in a public distribution or a public securities transaction. 

(s) The terms “register,” “registered” and “registration” shall refer to
(i) a registration effected by preparing and filing a registration statement in compliance with the Securities Act, and the declaration or ordering of the effectiveness of such registration statement, or (ii) in the context of a public
offering in a jurisdiction other than the United States, a registration, qualification or filing under the applicable securities laws of such other jurisdiction. 
 (t) “Registration Expenses” shall mean all expenses, except as otherwise stated below, incurred by the Company in complying with Sections 2.5, 2.6 and 2.7 hereof, including,
without limitation, all registration, qualification and filing fees, printing expenses, escrow fees, fees and disbursements of counsel for the Company, blue sky fees and expenses, the expense of any special audits incident to or required by any such
registration (but excluding the compensation of regular employees of the Company which shall be paid in any event by the Company) and the reasonable fees and disbursements of one counsel for all Holders, but excluding Selling Expenses. 

(u) “Restricted Securities” shall mean the securities of the Company required to bear the legend(s) set forth in
Section 2.3 hereof. 
 (v) “Securities Act” shall mean the United States Securities Act of 1933, as
amended. 
 (w) “Selling Expenses” shall mean all underwriting discounts, selling commissions and share
transfer taxes applicable to the securities registered by the Holders and, except as set forth above in the definition of “Registration Expenses,” all fees and disbursements of counsel for any Holder. 

 

	 	2.	Restrictions on Transfer; Registration Rights. 

 2.1 Restrictions on Transferability. The Restricted Securities shall not be sold, assigned, transferred or pledged except upon the conditions specified in this Section 2, which
conditions are intended to ensure compliance with the provisions of the Securities Act. Except in connection with (a) transfers made pursuant to an effective registration statement (or comparable qualification in a foreign jurisdiction), or
(b) transfers made pursuant to Rule 144 at a time when the Company is subject to the reporting obligations of the Exchange Act (each of the foregoing, a “Permitted Transfer”), each Holder will cause any proposed purchaser,
assignee, transferee or pledgee of any such shares held by Holder to agree to take and hold such securities subject to the provisions and upon the conditions specified in this Section 2. 

  
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 2.2 No Transfer. The Company shall not be required (a) to transfer on its
books any Restricted Securities which shall have been sold or transferred in violation of any of the provisions set forth in this Agreement, or (b) to treat as owner of such Restricted Securities or to accord the right to vote as such owner or
to pay dividends to any transferee to whom such Restricted Securities shall have been so transferred. 
 2.3
Restrictive Legends. All certificates representing Registrable Securities subject to the provisions of this Agreement shall (unless otherwise permitted by the provisions of Section 2.4 below) have endorsed thereon one or more of the
following legends, as appropriate, substantially in the following form (in addition to any legend required under applicable federal, state, local or non-U.S. law and any other agreements by and among the Company and the Investors): 

“THE SECURITIES REPRESENTED HEREBY HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE
“ACT”). SUCH SECURITIES MAY NOT BE TRANSFERRED UNLESS (A) A REGISTRATION STATEMENT UNDER THE ACT IS IN EFFECT AS TO SUCH TRANSFER OR (B) PURSUANT TO RULE 144, OR (C) IN THE OPINION OF THE COMPANY, REGISTRATION UNDER
THE ACT IS UNNECESSARY IN ORDER FOR SUCH TRANSFER TO COMPLY WITH THE ACT.” 
 “THE SECURITIES REPRESENTED HEREBY HAVE
NOT BEEN REGISTERED UNDER THE U.S. SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD WITHIN THE UNITED STATES OR TO, OR FOR THE ACCOUNT OR BENEFIT OF, U.S. PERSONS, EXCEPT AS SET FORTH
BELOW. BY ITS ACQUISITION HEREOF, THE HOLDER, IF NOT A U.S. PERSON: (1) REPRESENTS THAT IT IS NOT A U.S. PERSON AND IS ACQUIRING THESE SHARES IN AN OFFSHORE TRANSACTION; (2) AGREES THAT IT WILL NOT RESELL OR OTHERWISE TRANSFER THESE SHARES
EXCEPT (A) TO THE COMPANY OR ANY SUBSIDIARY THEREOF, (B) PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE ACT, (C) INSIDE THE UNITED STATES, TO A QUALIFIED INSTITUTIONAL BUYER IN COMPLIANCE WITH RULE 144A UNDER THE ACT,
(D) INSIDE THE UNITED STATES, TO AN ACCREDITED INVESTOR THAT, PRIOR TO SUCH TRANSFER, FURNISHES TO THE COMPANY A SIGNED LETTER CONTAINING CERTAIN REPRESENTATIONS AND AGREEMENTS RELATING TO THE RESTRICTIONS ON TRANSFER OF THESE SHARES (THE FORM
OF WHICH LETTER CAN BE OBTAINED FROM THE COMPANY), (E) OUTSIDE THE UNITED STATES, IN AN OFFSHORE TRANSACTION IN COMPLIANCE WITH RULES 904 AND 905 UNDER THE ACT OR (F) PURSUANT TO THE EXEMPTION FROM REGISTRATION PROVIDED BY RULE 144 UNDER
THE ACT (IF AVAILABLE); AND (3) AGREES THAT IT WILL GIVE EACH PERSON TO WHOM THESE SHARES ARE TRANSFERRED A NOTICE 

  
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SUBSTANTIALLY TO THE EFFECT OF THIS LEGEND. IN CONNECTION WITH ANY TRANSFER OF THESE SHARES PURSUANT TO CLAUSES (C), (D) OR (F) ABOVE, THE HOLDER MUST, PRIOR TO SUCH TRANSFER, FURNISH
TO THE COMPANY SUCH CERTIFICATIONS, LEGAL OPINIONS OR OTHER INFORMATION AS THE COMPANY MAY REASONABLY REQUIRE TO CONFIRM THAT SUCH TRANSFER IS BEING MADE PURSUANT TO AN EXEMPTION OR IN A TRANSACTION NOT SUBJECT TO THE REGISTRATION REQUIREMENTS OF
THE ACT. AS USED HEREIN, THE TERMS ‘OFFSHORE TRANSACTION,’ ‘UNITED STATES,’ AND ‘U.S. PERSON’ HAVE THE MEANING GIVEN TO THEM BY REGULATION S UNDER THE ACT.” 

“THE SHARES REPRESENTED BY THIS CERTIFICATE ARE SUBJECT TO A LOCK-UP PERIOD OF UP TO 180 DAYS FOLLOWING THE EFFECTIVE DATE OF A
REGISTRATION STATEMENT OF THE COMPANY FILED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (OR SUCH OTHER PERIOD AS MAY BE REQUESTED BY THE COMPANY OR AN UNDERWRITER TO ACCOMMODATE REGULATORY RESTRICTIONS ON (I) THE PUBLICATION OR OTHER
DISTRIBUTION OF RESEARCH REPORTS AND (II) ANALYST RECOMMENDATIONS AND OPINIONS, INCLUDING, BUT NOT LIMITED TO, THE RESTRICTIONS CONTAINED IN NASD RULE 2711(F)(4) OR NYSE RULE 472(F)(4), OR ANY SUCCESSOR PROVISIONS OR AMENDMENTS THERETO), OR THE
COMPANY’S INITIAL PUBLIC OFFERING PURSUANT TO SECURITIES LAWS APPLICABLE TO AN OFFERING OF SECURITIES IN A JURISDICTION OTHER THAN THE UNITED STATES, AS SET FORTH IN AN AGREEMENT BETWEEN THE COMPANY AND THE ORIGINAL HOLDER OF THESE SHARES, A
COPY OF WHICH MAY BE OBTAINED AT THE PRINCIPAL OFFICE OF THE COMPANY. SUCH LOCK-UP PERIOD IS BINDING ON TRANSFEREES OF THESE SHARES.” 
 Each Holder consents to the Company making a notation on its records and giving instructions to any transfer agent of the Preference Shares or the Ordinary Shares in order to implement the restrictions on
transfer established in this Section 2. 
 2.4 Notice of Proposed Transfers. The holder of each certificate
representing Restricted Securities by acceptance thereof agrees to comply in all respects with the provisions of this Section 2.4. Prior to any proposed sale, assignment, transfer, charge or pledge of any Restricted Securities (other than
(a) a transfer not involving a change in beneficial ownership, (b) in transactions involving the distribution without consideration of Restricted Securities by the holder to any of its partners, members, affiliates or retired partners or
members, or to the estate of any of its partners or members or retired partners or members, or (c) a Permitted Transfer), the holder thereof shall give written notice to the Company of such holder’s intention to effect such transfer,
charge sale, assignment or pledge. Each such notice shall describe the manner and circumstances of the proposed transfer, charge sale, assignment or pledge in sufficient detail, and if requested by the Company, shall be accompanied, at such
holder’s expense by either (i) a written opinion of legal counsel who shall be, and whose legal opinion shall be, reasonably satisfactory to the Company addressed to the Company, to the effect that the proposed transfer of the Restricted
Securities may 

  
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be effected without registration under the Securities Act, (ii) a “no action” letter from the Commission to the effect that the transfer of such securities without registration
will not result in a recommendation by the staff of the Commission that action be taken with respect thereto, or (iii) other evidence, reasonably satisfactory to the Company, that such transaction complies with applicable securities laws,
whereupon the holder of such Restricted Securities shall be entitled to transfer such Restricted Securities in accordance with the terms of the notice delivered by the holder to the Company. The transferees shall be bound by the obligations of the
transferor in this Agreement and other shareholder agreements, including the Standoff Agreement (as defined in paragraph 2.14) below. Each certificate evidencing the Restricted Securities transferred as above provided (other than a Permitted
Transfer) shall bear the appropriate restrictive legends set forth in Section 2.3 above, except that such certificate shall not bear such restrictive legends if in the opinion of counsel for such holder and the Company such legend is not
required in order to establish compliance with any provision of the Securities Act. 
 2.5 Demand Registration.

 (a) Request for Registration. In case the Company shall receive from Initiating Holders a written request that
the Company effect any registration, qualification or compliance with respect to all or a part of the Registrable Securities, the gross cash proceeds of which equals or exceeds US$40,000,000.00, the Company will: 

(i) promptly give written notice of the proposed registration, qualification or compliance to all other Holders; and 

(ii) as soon as practicable, use its best efforts to effect such registration, qualification or compliance (including, without
limitation, appropriate qualification under applicable blue sky or other state securities laws and appropriate compliance with applicable regulations issued under the Securities Act and any other governmental requirements or regulations) as may be
so requested and as would permit or facilitate the sale and distribution of all or such portion of such Registrable Securities as are specified in such request, together with all or such portion of the Registrable Securities of any Holder or Holders
joining in such request as are specified in a written request received by the Company within twenty (20) days after receipt of such written notice from the Company; provided, however, that the Company shall not be obligated to
take any action to effect any such registration, qualification or compliance pursuant to this Section 2.5: 
 (1)
in any particular jurisdiction in which the Company would be required to execute a general consent to service of process in effecting such registration, qualification or compliance unless the Company is already subject to service in such
jurisdiction and except as may be required by the Securities Act; 
 (2) prior to six (6) months after the
effective date of the Company’s first registered public offering of its equity securities in the jurisdiction in which the Initiating Holders have requested such registration be effected or five (5) years after the First Closing (as
defined in the B-1 Extension Purchase Agreement), whichever is earlier; 
 (3) during the period starting with the date
sixty (60) days prior to the Company’s estimated date of filing of, and ending on the date six (6) months immediately following the effective date of, any registration statement pertaining to securities of the

  
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Company (other than a registration of securities in a transaction under Rule 145 promulgated under the Securities Act (“Rule 145”) or with respect to an employee
benefit plan), provided that the Company is actively employing in good faith all reasonable efforts to cause such registration statement to become effective; 
 (4) after the Company has effected two (2) such registrations pursuant to this subparagraph 2.5(a), and such registrations have been declared or ordered effective; or 

(5) if the Initiating Holders may dispose of shares of Registrable Securities pursuant to a registration statement on Form S-3 or
Form F-3 under the Securities Act or any successor forms thereto (“Form S-3/F-3”) pursuant to a request made under Section 2.7 hereof. 
 Notwithstanding the foregoing, in the event (i) the Initiating Holders have requested a registration to be effected in a jurisdiction other than the United States, (ii) the Company has not
previously effected a registration in such jurisdiction, and (iii) the Board determines in its sole discretion that such registration would impose materially more burdensome or costly obligations on the part of the Company as compared to those
to which the Company would be subject if the request was for a registration to be effected in the United States, then in such event, the Company shall not be obligated to effect such registration in such jurisdiction but shall be obligated to effect
such registration in the United States. 
 (b) Underwriting. In the event that a registration pursuant to
Section 2.5 is for a registered public offering involving an underwriting, the Company shall so advise the Holders as part of the notice given pursuant to Section 2.5(a)(i). In such event, the right of any Holder to registration pursuant
to Section 2.5 shall be conditioned upon such Holder’s participation in the underwriting arrangements required by this Section 2.5, and the inclusion of such Holder’s Registrable Securities in the underwriting to the extent
requested shall be limited to the extent provided herein. 
 The Company shall (together with all Holders proposing to
distribute their securities through such underwriting) enter into an underwriting agreement in customary form with the managing underwriter selected for such underwriting by the Company, but subject to reasonable approval of a majority in interest
of the Initiating Holders (based on Registrable Securities requested to be included in such registration). Notwithstanding any other provision of this Section 2.5, if the managing underwriter advises the Initiating Holders in writing that
marketing factors require a limitation of the number of shares to be underwritten, then the Company shall so advise all holders of Registrable Securities and the number of shares of Registrable Securities that may be included in the registration and
underwriting shall be allocated, among all Holders in proportion, as nearly as practicable, to the respective amounts of Registrable Securities held by such Holders at the time of filing the registration statement; provided, however,
that the number of shares of Registrable Securities to be included in such underwriting and registration shall not be reduced unless all other securities of the Company are first entirely excluded from the underwriting and registration. No
Registrable Securities excluded from the underwriting by reason of the underwriter’s marketing limitation shall be included in such registration. To facilitate the allocation of shares in accordance with the above provisions, the Company or the
underwriters may round the number of shares allocated to any Holder to the nearest 100 shares. 

  
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 If any Holder of Registrable Securities disapproves of the terms of the underwriting, such
person may elect to withdraw therefrom by written notice to the Company, the managing underwriter and the Initiating Holders. The Registrable Securities and/or other securities so withdrawn shall also be withdrawn from registration, and such
Registrable Securities shall not be transferred in a public distribution prior to ninety (90) days after the effective date of such registration, or such other shorter period of time as the underwriters may require. 

2.6 “Piggyback” Registration. 
 (a) Notice of Registration. If at any time or from time to time the Company shall determine to register any of its securities, either for its own account or the account of a security holder
or holders, other than (i) a registration relating solely to employee benefit plans, or (ii) a registration relating solely to a Rule 145 transaction, the Company will: 

(i) promptly give to each Holder written notice thereof; and 

(ii) include in such registration (and any related qualification under blue sky laws or other compliance), and in any
underwriting involved therein, all the Registrable Securities specified in a written request or requests, made within twenty (20) days after receipt of such written notice from the Company, by any Holder. 

(b) Underwriting. If the registration of which the Company gives notice is for a registered public offering involving an
underwriting, the Company shall so advise the Holders as a part of the written notice given pursuant to Section 2.6(a)(i). In such event the right of any Holder to registration pursuant to Section 2.6 shall be conditioned upon such
Holder’s participation in such underwriting and the inclusion of Registrable Securities in the underwriting to the extent provided herein. All Holders proposing to distribute their securities through such underwriting shall (together with the
Company and the other holders distributing their securities through such underwriting) enter into an underwriting agreement in customary form with the managing underwriter selected for such underwriting by the Company. Notwithstanding any other
provision of this Section 2.6, if the managing underwriter determines that marketing factors require a limitation of the number of shares to be underwritten, the managing underwriter may limit the number of Registrable Securities to be included
in such registration and underwriting. Except in connection with an IPO, no such reduction shall reduce the amount of Registrable Securities of the selling Holders included in the registration below thirty percent (30%) of the total amount of
securities included in such registration. Notwithstanding the foregoing, if such offering is an IPO, any or all of the Registrable Securities of the Holders may be excluded in accordance with Section 2.6(a), provided that any other shares other
than (i) shares being offered by the Company or (ii) shares being offered by such other party at whose request such registration is being undertaken (provided the rights pursuant to which such other party requested such registration were
agreed to pursuant to Section 2.17) shall be excluded from registration prior to the exclusion of the Registrable Securities of the Holders. The Company shall so advise all Holders and other holders distributing their securities through such
underwriting and the number of shares of Registrable Securities that may be included in the registration and underwriting shall be allocated among all the Holders in proportion, as nearly as practicable, to the respective amounts of Registrable
Securities held by such Holder at the time of filing the Registration Statement pursuant to which the securities of the Company shall be marketed (generally referred to as the “Reds”). To facilitate the allocation of shares in
accordance with the above provisions, the Company may round the number of shares allocated to 

  
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any Holder or holder to the nearest 100 shares. If any Holder or holder disapproves of the terms of any such underwriting, he may elect to withdraw therefrom by written notice to the Company and
the managing underwriter. Any securities excluded or withdrawn from such underwriting shall be withdrawn from such registration, and shall not be transferred in a public distribution prior to ninety (90) days after the effective date of the
registration statement relating thereto, or such other shorter period of time as the underwriters may require. 
 (c)
Right to Terminate Registration. The Company shall have the right to terminate or withdraw any registration initiated by it under this Section 2.6 prior to the effectiveness of such registration whether or not any Holder has elected
to include securities in such registration. Selling Expenses of such withdrawn registration shall be borne by the Company. 

2.7 Registration on Form S-3/F-3. 
 (a) If any Holder or Holders who in the aggregate hold at least 15% of the Registrable Securities then outstanding request that the Company file a registration statement on Form S-3/F-3 for a
public offering of shares of the Registrable Securities, the reasonably anticipated gross cash proceeds of which would exceed US$1,000,000.00, and the Company is a registrant entitled to use Form S-3/F-3 to register the Registrable Securities for
such an offering, the Company shall use its best efforts to cause such Registrable Securities to be registered for the offering on such form and to cause such Registrable Securities to be qualified in such jurisdictions as such Holder or Holders may
reasonably request; provided, however, that the Company shall not be required to effect more than two (2) registrations pursuant to this Section 2.7 in any twelve (12) month period. The Company shall inform other Holders
of the proposed registration and offer them the opportunity to participate. The substantive provisions of Section 2.6(b) shall be applicable to each registration initiated under this Section 2.7. 

(b) Notwithstanding the foregoing, the Company shall not be obligated to take any action pursuant to this Section 2.7:
(i) in any particular jurisdiction in which the Company would be required to execute a general consent to service of process, in effecting such registration, qualification or compliance unless the Company is already subject to service in such
jurisdiction and except as may be required by the Securities Act; or (ii) during the period starting with the date sixty (60) days prior to the Company’s estimated date of filing of, and ending on the date six (6) months
immediately following, the effective date of any registration statement pertaining to securities of the Company (other than a registration of securities in a Rule 145 transaction or with respect to an employee benefit plan), provided
that the Company is actively employing in good faith all reasonable efforts to cause such registration statement to become effective. 
 2.8 Expenses of Registration. All Registration Expenses incurred in connection with all registrations pursuant to Sections 2.5, 2.6 and 2.7 shall be borne by the Company;
provided, however, that the Company shall not be required to pay for any expenses of any registration proceeding begun pursuant to Section 2.5 if the registration request is subsequently withdrawn at the request of the Holders of
a majority of the Registrable Securities to be registered (in which case all participating Holders shall bear such expenses), unless the Holders of a majority of the Registrable Securities agree to forfeit their right to one demand registration
pursuant to Section 2.5; provided further however, that if the requested registration is withdrawn and at the time of such withdrawal the Holders have learned of a material adverse change in the condition, business or prospects of the
Company from that known to the Holders at the time of their request and have withdrawn the request 

  
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with reasonable promptness following disclosure by the Company of such material adverse change, then the Holders shall not be required to pay any of such expenses or forfeit a demand registration
pursuant to Section 2.5. All Selling Expenses shall be borne by the Holders of the securities so registered pro rata on the basis of the number of their shares so registered. 

2.9 Registration Procedures. In the case of each registration, qualification or compliance effected by the Company pursuant
to this Section 2, the Company will keep each Holder advised in writing as to the initiation of each registration, qualification and compliance and as to the completion thereof. At its expense the Company will: 

(a) prepare and file with the Commission a registration statement with respect to such securities and use its best efforts to
cause such registration statement to become and remain effective for at least ninety (90) days or until the distribution described in the Registration Statement has been completed; 

(b) prepare and file with the Commission such amendments and supplements to such registration statement and the prospectus used
in connection with such registration statement as may be necessary to comply with the provisions of the Securities Act with respect to the disposition of all securities covered by such registration statement for the period set forth in
subsection (a) above; 
 (c) furnish to the Holders participating in such registration and to the underwriters of
the securities being registered such reasonable number of copies of the registration statement, preliminary prospectus, final prospectus and such other documents as such underwriters may reasonably request in order to facilitate the public offering
of such securities; 
 (d) use its reasonable efforts to register and qualify the securities covered by such
registration statement under such other securities or Blue Sky laws of such jurisdictions as shall be reasonably requested by the Holders; provided that the Company shall not be required in connection therewith or as a condition thereto to
qualify to do business or to file a general consent to service of process in any such states or jurisdictions, unless the Company is already subject to service in such jurisdiction and except as may be required by the Securities Act; 

(e) in the event of any underwritten public offering, enter into and perform its obligations under an underwriting agreement, in
usual and customary form, with the managing underwriters of such offering. Each Holder participating in such underwriting shall also enter into and perform its obligations under such an agreement; 

(f) notify each Holder of Registrable Securities covered by such registration statement at any time when a prospectus relating
thereto is required to be delivered under the Securities Act of the happening of any event as a result of which the prospectus included in such registration statement, as then in effect, includes an untrue statement of a material fact or omits to
state a material fact required to be stated therein or necessary to make the statements therein not misleading in the light of the circumstances then existing. The Company will use reasonable efforts to amend or supplement such prospectus in order
to cause such prospectus not to include any untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein not misleading in the light of the circumstances then
existing; and 

  
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 (g) use its reasonable efforts to furnish, on the date that such Registrable
Securities are delivered to the underwriters for sale, if such securities are being sold through underwriters, (i) an opinion, dated as of such date, of the counsel representing the Company for the purposes of such registration, in form and
substance as is customarily given to underwriters in an underwritten public offering, addressed to the underwriters, if any, and (ii) a letter, dated as of such date, from the independent certified public accountants of the Company, in form and
substance as is customarily given by independent certified public accountants to underwriters in an underwritten public offering addressed to the underwriters. 
 2.10 Indemnification. 
 (a) To the extent permitted by law,
the Company will indemnify and hold harmless each Holder, each of its officers, directors and partners, legal counsel and accountants and each person controlling such Holder within the meaning of Section 15 of the Securities Act, with respect
to which registration, qualification or compliance has been effected pursuant to this Section 2, and each underwriter, if any, and each person who controls within the meaning of Section 15 of the Securities Act any underwriter, against all
expenses, claims, losses, damages and liabilities (or actions, proceedings or settlements in respect thereof) arising out of or based on: (i) any untrue statement (or alleged untrue statement) of a material fact contained or
incorporated by reference in any registration statement, any prospectus included in the registration statement, any issuer free writing prospectus (as defined in Rule 433 of the Securities Act), any issuer information (as defined in
Rule 433 of the Securities Act) filed or required to be filed pursuant to Rule 433(d) under the Securities Act or any other document incident to any such registration, qualification or compliance prepared by or on behalf of the
Company or used or referred to by the Company; (ii) any omission (or alleged omission) to state therein a material fact required to be stated therein or necessary to make the statements therein not misleading; or (iii) any violation (or
alleged violation) by the Company of the Securities Act, any state securities laws or any rule or regulation thereunder applicable to the Company and relating to action or inaction required of the Company in connection with any offering covered by
such registration, qualification or compliance, and the Company will reimburse each such Holder, each of its officers, directors, partners, legal counsel and accountants and each person controlling such Holder, each such underwriter and each person
who controls any such underwriter, for any legal and any other expenses reasonably incurred in connection with investigating and defending or settling any such claim, loss, damage, liability or action; provided that the Company will not be
liable in any such case to the extent that any such claim, loss, damage, liability, or action arises out of or is based on any untrue statement or omission based upon written information furnished to the Company by such Holder, any of such
Holder’s officers, directors, partners, legal counsel or accountants, any person controlling such Holder, such underwriter or any person who controls any such underwriter, and stated to be specifically for use therein; and provided,
further that, the indemnity agreement contained in this Section 2.10(a) shall not apply to amounts paid in settlement of any such loss, claim, damage, liability or action if such settlement is effected without the consent of the Company
(which consent shall not be unreasonably withheld or delayed). 
 (b) Each Holder will, if Registrable Securities held
by such Holder are included in the securities as to which such registration, qualification or compliance is being effected, indemnify the Company, each of its directors and officers, each underwriter, if any, of the Company’s securities covered
by such a registration statement, each person who controls the Company or such underwriter within the meaning of Section 15 of the Securities Act, and each other 

  
 -11-

 
such Holder, each of its officers, trustees and directors and each person controlling such Holder within the meaning of Section 15 of the Securities Act, against all claims, losses, damages
and liabilities (or actions in respect thereof) arising out of or based on any untrue statement (or alleged untrue statement) of a material fact contained in any such registration statement, prospectus, offering circular or other document, or any
omission (or alleged omission) to state therein a material fact required to be stated therein or necessary to make the statements therein not misleading, and will reimburse the Company, such other Holders, such directors, officers, trustees,
persons, underwriters or control persons for any legal or any other expenses reasonably incurred in connection with investigating or defending any such claim, loss, damage, liability or action, in each case to the extent, but only to the extent,
that such untrue statement (or alleged untrue statement) or omission (or alleged omission) is made in such registration statement, prospectus, offering circular or other document in reliance upon and in conformity with written information furnished
to the Company by an instrument duly executed by such Holder and stated to be specifically for use therein; provided, however, that the foregoing indemnity agreement is subject to the condition that, insofar as it relates to any untrue
statement, alleged untrue statement, omission or alleged omission made in a preliminary prospectus on file with the Commission at the time the registration statement becomes effective or in the Final Prospectus, such indemnity agreement shall not
inure to the benefit of any underwriter or any Holder, if there is no underwriter, if a copy of the Final Prospectus was not furnished to the person asserting the loss, liability, claim or damage at or prior to the time such action is required by
the Securities Act; provided, further, that the indemnity agreement contained in this Section 2.10(b) shall not apply to amounts paid in settlement of any such claim, loss, damage, liability or action if such settlement is
effected without the consent of the Holder, which consent shall not be unreasonably withheld or delayed. Notwithstanding the foregoing, the liability of each Holder under this subsection (b) shall be limited in an amount equal to the proceeds
of the shares sold by such Holder, less any applicable underwriting discounts and commissions; provided, however, such limitation shall not apply in the case of fraud by such Holder. 

(c) Each Party entitled to indemnification under this Section 2.10 (the “Indemnified Party”) shall give
notice to the Party required to provide indemnification (the “Indemnifying Party”) promptly after such Indemnified Party has actual knowledge of any claim as to which indemnity may be sought, and the Indemnifying Party shall have
the option to assume the defense of any such claim or any litigation resulting therefrom, provided that counsel for the Indemnifying Party, who shall conduct the defense of such claim or litigation, shall be approved by the Indemnified Party
(whose approval shall not unreasonably be withheld), and the Indemnified Party may participate in such defense at such Party’s expense, and provided further that the failure of any Indemnified Party to give notice as provided herein
shall not relieve the Indemnifying Party of its obligations under this Section 2 unless the failure to give such notice is materially prejudicial to an Indemnifying Party’s ability to defend such action and provided further, that
the Indemnifying Party shall not assume the defense for matters as to which there is a conflict of interest or separate and different defenses. No claim may be settled without the consent of the Indemnifying Party (which consent shall not be
unreasonably withheld). No Indemnifying Party, in the defense of any such claim or litigation, shall, except with the consent of each Indemnified Party, consent to entry of any judgment or enter into any settlement which does not include as an
unconditional term thereof the giving by the claimant or plaintiff to such Indemnified Party of a release from all liability in respect to such claim or litigation. 

  
 -12-

 (d) If the indemnification provided for in this Section 2.10 is held by a court
of competent jurisdiction to be unavailable to an Indemnified Party with respect to any loss, liability, claim, damage or expense referred to therein, then the Indemnifying Party, in lieu of indemnifying such Indemnified Party hereunder, shall
contribute to the amount paid or payable by such Indemnified Party as a result of such loss, liability, claim, damage or expense in such proportion as is appropriate to reflect the relative fault of the Indemnifying Party on the one hand and of the
Indemnified Party on the other in connection with the statements or omissions that, resulted in such loss, liability, claim, damage or expense as well as any other relevant equitable considerations; provided that in no event shall any
contribution by a Holder under this subsection 2.10(d), plus all amounts paid by such Holder pursuant to Section 2.10(b), exceed the net proceeds from the public offering received by such Holder (calculated as set forth in the last sentence of
Section 2.10(b)), except in the case of willful fraud by such Holder. The relative fault of the Indemnifying Party and of the Indemnified Party shall be determined by reference to, among other things, whether the untrue or alleged untrue
statement of a material fact or the omission to state a material fact relates to information supplied by the Indemnifying Party or by the Indemnified Party, and the parties’ relative intent, knowledge, access to information, and opportunity to
correct’ or prevent’ such statement or omission. 
 (e) The Company may enter into indemnification and
contribution provisions in any underwriting agreement entered into in connection with the public offering if so requested by the underwriters. Notwithstanding the foregoing, to the extent that the provisions on indemnification and contribution
contained in the underwriting agreement entered into in connection with the underwritten public offering are in conflict with the foregoing provisions, the provisions in the underwriting agreement shall control. 

(f) The obligations of the Company and the Holders under this Section 2.10 shall survive the completion of any offering of
Registrable Securities in a registration statement under this Section 2, and otherwise. 
 2.11 Information by
Holder. It shall be a condition precedent to the obligations of the Company to take any action pursuant to this Section 2 with respect to the Registrable Securities of any selling holder that such Holder shall furnish to the Company such
information regarding such Holder or Holders, the Registrable Securities held by them and the distribution proposed by such Holder or Holders as the Company may reasonably request in writing and as shall be required in connection with any
registration, qualification or compliance referred to in this Section 2. The Company shall have no obligation with respect to any registration requested pursuant to Section 2.5 or 2.7 of this Agreement if, as a result of the application of
the preceding sentence, the number of shares or the anticipated aggregate offering price of the Registrable Securities to be included in the registration does not equal or exceed the number of shares or the anticipated aggregate offering price
required to originally trigger the Company’s obligation to initiate such registration as specified in subsection 2.5(a) or subsection 2.7(a), whichever is applicable. 
 2.12 Rule 144 Reporting. With a view to making available the benefits of certain rules and regulations of the Commission which may at any time permit the sale of the Restricted
Securities to the public without registration, after such time as a public market exists for the Ordinary Shares of the Company, the Company agrees to use its best efforts to: 

(a) make and keep public information available, as those terms are understood and defined in Rule 144 under the Securities
Act, at all times after the effective date that the Company becomes subject to the reporting requirements of the Securities Act or the Exchange Act; 

  
 -13-

 (b) file with the Commission in a timely manner all reports and other documents
required of the Company under the Securities Act and the Exchange Act (at any time after it has become subject to such reporting requirements); and 
 (c) so long as the Investor owns any Restricted Securities, to furnish to the Investor forthwith upon request a written statement by the Company as to its compliance with the reporting requirements
of said Rule 144 (at any time after ninety (90) days after the effective date of the first registration statement filed by the Company for an offering of its securities to the general public in the United States), and of the Securities Act
and the Exchange Act (at any time after it has become subject to such reporting requirements), a copy of the most recent annual or quarterly report of the Company, and such other reports and documents of the Company and other information in the
possession of or reasonably obtainable by the Company as the Investor may reasonably request in availing itself of any rule or regulation of the Commission allowing the Investor to sell any such securities without registration. 

2.13 Transfer of Registration Rights. The rights to cause the Company to register securities granted to each Holder under
Sections 2.5, 2.6 and 2.7 may be assigned to a transferee or assignee in connection with any transfer or assignment of Registrable Securities by any Holder, provided that: (a) such transfer may otherwise be effected in accordance
with applicable securities laws; (b) the Company is given prompt notice of the transfer; (c) such assignee or transferee agrees to be bound by the terms of this Agreement; and (d) such assignee or transferee is (i) any partner or
retired partner of any Holder which is a partnership (or any member or retired member of any Holder which is a limited liability company), (ii) any affiliate of any Holder, or (iii) any other transferee reasonably acceptable to the Company
who acquired at least one million (1,000,000) Registrable Securities, as adjusted for Recapitalizations (an “Eligible Transferee”). 
 2.14 Standoff Agreement. In connection with any public offering of the Company’s equity securities pursuant to (a) a registration statement filed under the Securities Act or
(b) securities laws applicable to an offering of securities in a jurisdiction other than the United States, upon request of the Company or the underwriters managing any underwritten offering of the Company’s securities, the Holders shall
not sell, make any short sale of, loan, grant any option for the purchase of, or otherwise dispose of any equity securities of the Company without the prior written consent of the Company or such underwriters, as the case may be, for such period of
time (not to exceed one hundred eighty (180) days) from the effective date of such registration (or such other period as may be requested by the Company or an underwriter to accommodate regulatory restrictions on (i) the publication or
other distribution of research reports and (ii) analyst recommendations and opinions, including, but not limited to, the restrictions contained in NASD Rule 2711(f)(4) or NYSE Rule 472(f)(4), or any successor provisions or amendments
thereto) as may be requested by the Company or such underwriters and will enter into a written form of agreement in such form reasonably requested by the underwriters (the “Standoff Agreement”) to effect the foregoing; provided
that all officers and directors of the Company and holders of at least one percent (1%) of the Company’s voting securities enter into similar agreements. Furthermore, the Company and any underwriter will not release any officer,
director or greater than one percent (1%) holder, in whole or in part, from their market stand-off obligations unless a proportionate amount of Registrable Securities held by each Holder is also released. 

  
 -14-

 2.15 Delay. If the Company shall furnish to such Holders a certificate signed
by the President of the Company stating that in the good faith judgment of the Board it would be seriously detrimental to the Company or its members for a registration statement to be filed in the near future, then the Company’s obligation to
use its best efforts to register, qualify or comply under Sections 2.5 or 2.7 shall be deferred for a period not to exceed sixty (60) days from the date of receipt of written request from the Initiating Holders; provided that such
right to delay a request shall be exercised by the Company not more than once in any twelve (12) month period. 
 2.16
No Injunction. No Holder shall have any right to obtain or seek an injunction restraining or otherwise delaying any such registration as the result of any controversy that might arise with respect to the interpretation or implementation
of this Section 2. 
 2.17 Limitation on Subsequent Registration Rights. The Company shall not, without the
consent of the Holders of a majority of the Registrable Securities then outstanding, enter into any agreement with any Holder or prospective holder of any securities of the Company that would grant such Holder or prospective holder any registration
rights on a parity with or senior to those granted to the Holders of Registrable Securities hereunder; provided that the Company shall not, without the consent of the Holders of a majority of the Series B-1 Shares, enter into any agreement
with any Holder or prospective holder of any securities of the Company or take any other action that would have the effect of negating or removing the registration rights of the Holders of Series B-1 Shares or would adversely affect the Holders of
Series B-1 Shares in a materially disproportionate manner as compared with the Holders of Series A Shares, taking into account the Original Issue Price of the Series B-1 Shares and the Original Issue Price of the Series A Shares.

 2.18 Termination. The rights to cause the Company to register securities granted to each Holder under
Sections 2.5, 2.6 and 2.7 shall expire upon the earlier of (a) such time as such Holder receives an opinion of counsel reasonably acceptable to such Holder (which may be regular outside corporate counsel to the Company (an opinion from
whom shall be deemed acceptable to such Holder)), which states that such Holder may sell all of such Holder’s securities pursuant to Rule 144 during any ninety (90) day period, and (b) three (3) years after an IPO. 

 

	 	3.	Covenants of the Company and the Investors. 

 3.1 Financial Information. The Company will mail the following reports (in accordance with the provisions set forth in Section 5.5 herein) to each Holder who, immediately prior to the
distribution of information as provided below, together with its affiliates, related individuals or entities, continues to hold at least five hundred thousand (500,000) Preference Shares, as adjusted for Recapitalizations (each, a
“Material Holder”): 
 (a) as soon as practicable after the end of each fiscal year, and in any event
within one hundred twenty (120) days thereafter, audited financial statements of the Company and its subsidiaries, if any, as of the end of such fiscal year, including a balance sheet, statement of income, statement of cash flows and notes to
the financial statements. Such year-end financial statements shall be prepared in reasonable detail and in accordance with international financial reporting standards (“IFRS”) or generally accepted accounting principles in the
United States (“GAAP”); 

  
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 (b) as soon as practicable, and in any event within forty-five (45) days, after
the end of the first, second and third quarterly accounting periods in each fiscal year of the Company, unaudited financial statements of the Company, including a balance sheet, statement of income, statement of cash flows and notes to the financial
statements, all prepared in accordance with international IFRS or GAAP; and 
 (c) as soon as practicable, and in any
event within thirty (30) days after the end of each of the first eleven (11) months of each fiscal year, unaudited monthly financial statements prepared in accordance with international IFRS or GAAP. 

A Material Holder’s rights under this Section 3.1 may be assigned to an Eligible Transferee in connection with the transfer of
registration rights provided for in Section 2.13 above. 
 3.2 Inspection. The Company will afford to each
Material Holder and to such Material Holder’s accountants, counsel and other representatives reasonably acceptable to the Company, reasonable access during normal business hours to all of the Company’s respective properties, books,
contracts, commitments and records, including shareholder lists along with any information distributed to the Board. The Company also will furnish promptly to such Material Holders (a) a copy of each report, schedule, registration statement and
other document filed or received by it pursuant to the requirements of federal and state securities laws, and (b) all other information concerning its business, properties and personnel as such Material Holder may reasonably request. Each
Material Holder shall have such other access to management and information as is necessary for it to comply with applicable laws and regulations and reporting obligations. The Company shall not be required to disclose details of contracts with or
work performed for specific customers and other business partners where to do so would violate confidentiality obligations to those parties and such parties have not consented to disclosure; provided that the Company shall be required to take
all reasonable steps to obtain the required consents to disclose such details as may be requested by Material Holders. Material Holders may exercise their rights under this Section 3.2 only for purposes reasonably related to its interests under
this Agreement and related agreements. 
 3.3 Options. Unless otherwise approved by the Board,
options to purchase equity securities of the Company issued to employees, directors and consultants shall be subject to four (4) year vesting, with twenty five percent (25%) vesting on the first anniversary of commencement of services with
the Company and one forty-eighth (1/48th) vesting on
a monthly basis thereafter. 
 3.4 Confidential Information and Invention Assignment Agreements. The Company will
enter into Confidential Information and Invention Assignment Agreements, substantially in the form attached hereto as Exhibit C, with all employees and consultants. 

3.5 “Key Person” Life Insurance. The Company will obtain and maintain “key person” life insurance
policy with respect to Jeff Yordon in the amount of US$5,000,000.00, with the proceeds payable to the Company. 

  
 -16-

 3.6 Indemnification Matters. The Company will enter into indemnification
agreements in customary forms with its directors and officers, and shall obtain director and officer liability insurance upon terms and conditions typical for business such as the Company. Subject to the approval of the Board, the Company shall
maintain director and officer insurance in amounts typical for its industry as determined by its Board. The Company’s charter documents shall provide for elimination of the liability of directors to the maximum extent permitted by law.

 3.7 Expenses; Meetings; Committees. The Company shall reimburse the reasonable out-of-pocket travel
expenses of each director incurred to attend Board or committee meetings, as well as any other travel expenses approved by the Board. 
 3.8 Passive Foreign Investment Company. The Company shall use commercially reasonable efforts to avoid being a passive foreign investment company (“PFIC”) as defined in
section 1297 of the Internal Revenue Code. The Company shall determine prior to March 1 of each year, whether it was a PFIC for the immediate preceding taxable year ending December 31. In the event the Company was a PFIC
for such taxable year, it shall provide to each Investor a PFIC Annual Information Statement for such year in the form attached as Exhibit D no later than March 11 of the subsequent year and shall grant each Investor access to
such other Company information as may be required for the purposes of making and maintaining a qualified election fund (“QEF”) election and filing its U.S. federal income tax returns. 

3.9 Classification as U.S. Corporation. The company shall take such action as may be necessary to maintain, at all times,
its classification as a corporation for U.S. federal income tax purposes. 
 3.10 Drag-Along Rights. 

(a) Prior to an IPO, in the event that the Board and members holding at least 50% of the Company’s outstanding Ordinary
Shares and Preference Shares, voting together as a single class on an as-converted basis (the “Accepting Members”), approve a Deemed Liquidation Event in which the aggregate consideration to be paid to the shareholders of the
Company, less any required withholding, holdbacks or escrows, is no less than US$700,000,000 (an “Approved Sale”), then the remaining members (collectively, the “Remaining Members”) shall each consent to, vote for
and raise no objections to the Approved Sale. If the Approved Sale will take the form of an asset sale, merger or consolidation, the Remaining Members shall vote in favor of such transaction and shall waive any appraisal rights or dissenters’
rights in connection with such transaction. If the Approved Sale is structured as a sale of the shares of the Company, each Remaining Member shall agree to sell all shares in the Company then held by such Remaining Member on the terms and conditions
approved by the Accepting Members. All shares transferred by the Remaining Members pursuant to this Section 3.10 shall be sold at the same price and otherwise treated identically with the shares of the same class and series being sold by the
Accepting Members in all respects. The Remaining Members shall each take such actions as may be reasonably required and otherwise cooperate in good faith with the Accepting Members in connection with consummating the Approved Sale, including the
execution of such agreements and such instruments and other actions reasonably necessary to effectuate the allocation and distribution of the aggregate consideration upon the Approved Sale. 

  
 -17-

 (b) The Accepting Members shall give the Remaining Members at least ten
(10) days prior written notice of any Approved Sale as to which the Accepting Members intend to exercise their rights under this Section 3.10 (which 10-day period may be shortened or waived by holders of a majority of the shares held by
all of the Remaining Members, voting together as a single class on an as-converted basis). Such notices shall be delivered by the Accepting Members to the Company to the attention of the President, and the Company shall thereupon cause such notices
to be transmitted to each Remaining Member at its registered address maintained with the Company. Charges for such transmittal shall be against the account of the Accepting Members, who will be required to indicate the method of transmission to be
used by the Company in this regard (e.g., regular post, express courier, etc.). The Company may require advance payment of funds from the Accepting Members to cover the costs of transmitting such notices. 

(c) In furtherance of the foregoing, the Company is authorized to sell the shares held by the Remaining Members on behalf of the
Remaining Members, and pursuant to such authorization, may execute all documents necessary to effectuate the sale and transfer of such shares on behalf of the Remaining Members. Notwithstanding the foregoing provisions of this Section 3.10, the
Remaining Members shall not be obligated to sell their shares, and the Company shall not be authorized to sell the shares held by the Remaining Members in accordance with the preceding sentence, if the Accepting Members do not complete the Approved
Sale on terms and conditions that are in all material respects identical to those specified in the notice. 
 3.11
Protective Provisions. 
 (a) For so long as at least five million (5,000,000) Series A Shares (as
adjusted for Recapitalizations) remain outstanding, the Company shall not take any of the following actions, either directly or indirectly by merger, consolidation, amendment to the Articles or otherwise, without first obtaining the consent of
holders of a majority of the Series A Shares then outstanding, voting as a single class: 
 (i) cause or permit the
redemption, repurchase or other acquisition, directly or indirectly, of shares of the Company other than (A) the Company’s Ordinary Shares that are being repurchased at a price not higher than the original purchase price pursuant to option
agreements or restricted share purchase agreements between the Company and any employees, officers, directors, consultants or service providers or pursuant to a right of first refusal held by the Company and (B) a redemption effected by the
Company in accordance with Article 13 or Article 16 of the Articles to allow for the conversion of Preference Shares into Ordinary Shares; 
 (ii) declare or take any action resulting in payment of dividends or distributions with respect to the share capital of the Company (other than redemptions and repurchases permitted under
(a) above); 
 (iii) increase or decrease the authorized number of shares of any class or series of the
Company’s share capital; 
 (iv) amend or determine any provisions of the Memorandum or the Articles, or change any
rights, preferences, privileges or restrictions applicable to the holders of Series A Shares, except if there is no resulting materially disproportionate adverse effect on the holders of Series A Shares; provided,
however, that the increase or decrease of authorized shares of 

  
 -18-

 
any class or series of the Company’s share capital (other than the Series A Shares) or the authorization and issue of a new senior or pari passu class or series of securities shall
not be deemed to have a materially disproportionate adverse effect on the holders of Series A Shares; provided, further, that consent shall not be required in connection with a Qualified IPO in which Preference Shares are converted
into Ordinary Shares pursuant to Article 16 of the Articles; 
 (v) authorize, designate, reclassify, amend or issue, or
obligate the Company to do any of the foregoing with respect to, any class or series of equity securities, including any security exercisable for or convertible into any equity security, which is or will be senior to or pari passu with, the
Series A Shares with respect to any rights, preferences or privileges or restrictions other than the Series B Preference Shares and Series B-1 Shares and any warrant issued in connection with the issuance of Series B-1 Shares (and any equity
securities issued or issuable upon exercise of such warrant); 
 (vi) a voluntary dissolution or liquidation of the
Company; or 
 (vii) authorize, enter into or agree to a Deemed Liquidation Event (with the exception of an Approved
Sale) or Recapitalization. 
 (b) For so long as at least five million (5,000,000) Series A Shares (as
adjusted for Recapitalizations) remain outstanding, the Company shall not take any of the following actions, either directly or indirectly by merger, consolidation, amendment to the Articles or otherwise, without first obtaining the approval of a
majority of the Board, including at least two (2) Series A Directors: 
 (i) incur any indebtedness over
US$500,000 other than trade payables incurred in the ordinary course of business; 
 (ii) change the number of directors
on the Board; 
 (iii) adopt the annual budget and executive bonus goals; or 

(iv) incur any capital or product development expenditures over US$1,000,000 cumulative to any single company, product or
project, except as may be set forth in a budget that was previously approved by a majority of the Board, including at least two (2) Series A Directors. 
 (c) For so long as at least five million (5,000,000) Series B-1 Preference Shares (as adjusted for Recapitalizations) remain outstanding, the Company shall not take any of the following
actions, either directly or indirectly by merger, consolidation, amendment to the Articles or otherwise, without first obtaining the approval of a majority of the Board, including the Series B-1 Director (as defined in the Articles): 

(i) amend or determine any provisions of the Memorandum or the Articles, or change any rights, preferences, privileges or
restrictions applicable to the holders of Series B-1 Shares, except if there is no resulting materially disproportionate adverse effect on the holders of Series B-1 Shares; provided, however, that the increase or
decrease of authorized shares of any class or series of the Company’s share capital (other than the Series B-1 Shares) or the 

  
 -19-

 
authorization and issue of a new senior or pari passu class or series of securities shall not be deemed to have a materially disproportionate adverse effect on the holders of Series B-1
Shares; provided, further, that consent shall not be required in connection with a Qualified IPO in which Preference Shares are converted into Ordinary Shares pursuant to Article 16 of the Articles; 

(ii) sale or disposition of the whole or a substantial part (more than 25% of the assets on a consolidated basis) of the
business, goodwill or assets of the Company or any material subsidiary of the Company through sale, merger, acquisition, consolidation, or reorganization involving a change of control of the company in which the consideration for the Company taken
as a whole is less than US$700,000,000 (less any required withholding, holdbacks or escrows); 
 (iii) a voluntary
dissolution or liquidation of the Company; 
 (iv) change or expansion of the business scope of the Company; 

(v) any acquisition of or any investments in entities or businesses outside of the existing business scope of the company or any
acquisition involving consideration in excess of US$20,000,000; 
 (vi) cause or permit the redemption, repurchase or
other acquisition, directly or indirectly, of shares of the Company other than (A) the Company’s Ordinary Shares that are being repurchased at a price not higher than the original purchase price pursuant to option agreements or restricted
share purchase agreements between the Company and any employees, officers, directors, consultants or service providers or pursuant to a right of first refusal held by the Company and (B) a redemption effected by the Company in accordance with
Article 13 or Article 16 of the Articles to allow for the conversion of Preference Shares into Ordinary Shares; or 
 (vii)
authorize, enter into or agree to a Deemed Liquidation Event (with the exception of an Approved Sale) or Recapitalization. 

(d) For so long as at least five million (5,000,000) Series B-1 Preference Shares (as adjusted for Recapitalizations)
remain outstanding, the Company shall not take any of the following actions, either directly or indirectly by merger, consolidation, amendment to the Articles or otherwise, without first obtaining the approval of: (i) to the extent there are
six (6) or more Directors sitting on the Board, five (5) Directors and (ii) to the extent there are five (5) or fewer Directors sitting on the Board, a majority of the Board including at least one (1) of the Series B-1
Director, the Ordinary Share Director or the Independent Director: 
 (i) approval of any related party transaction (or
series of related transactions) involving consideration or value in excess of US$20,000; provided that the interested director(s) (if any) shall be required to disclose their interest therein and abstain from deliberation and voting therefor
(but shall be counted for the purposes of quorum); provided further that if the previous proviso is not met, such transaction(s) must be approved by a majority of the Board, including the Series B-1 Director if such Director is not an interested
director; 
 (ii) incur additional indebtedness, commitments or guarantees of indebtedness in excess of US$5,000,000;

  
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 (iii) approval of any new option plans or other equity incentive arrangements or
grant of incentive options; 
 (iv) approval of annual budget or material amendment thereof; 

(v) any single expenditure in excess of US$1,000,000 or expenditures in excess of US$5,000,000 in any 12-month period which are
not included in an approved annual budget; 
 (vi) determination of timing, venue and valuation of any IPO of the
Company other than a Qualified IPO; or 
 (vii) appointment of the Company’s corporate officers. 

3.12 Protective ERISA Provisions. The Company shall not, either directly or indirectly by merger, consolidation, amendment
to the Articles or otherwise, permit ERISA Investors to hold or otherwise own 25% or more of the Preference Shares and/or the Ordinary Shares then outstanding without first obtaining the written consent of the ERISA Investors then currently holding
any Preference Shares or Ordinary Shares (as applicable), voting as a single class. 
 3.13 Termination of
Covenants. The covenants set forth in Sections 3.1 to 3.12 shall terminate and be of no further force or effect immediately prior to the earliest of: (a) the effectiveness of an IPO; (b) the effectiveness of a Deemed Liquidation Event;
and (c) with respect to Section 3.1 only, the date on which the Company is required to file reports with the Commission pursuant to Section 13 or Section 15(d) of the Exchange Act. 

3.14 ERISA Investor Identification. Mellon Bank, N.A. as Trustee for the Weyerhaeuser Company Master Retirement Trust
hereby represents to the Company and the other Investors that it is an ERISA Investor. 
  

	 	4.	Right of First Offer. 

 4.1 Right of First Offer. Subject to the terms and conditions specified in this Section 4.1, the Company hereby grants to each Material Holder, a right of first offer to purchase its
Pro Rata Share (as hereinafter defined) (in whole or in part) with respect to future sales by the Company of New Securities (as hereinafter defined). For purposes of this Section 4.1, a Material Holder’s “Pro Rata Share”
shall mean that number of New Securities that equals the ratio that (i) the number of Ordinary Shares issuable or issued upon conversion of the Preference Shares held by such Material Holder bears to (ii) the total number of Ordinary
Shares of the Company then outstanding (assuming full conversion and exercise of all convertible or exercisable securities, whether vested or unvested, then outstanding). Each time the Company proposes to issue or offer any shares of, or securities
convertible into or exercisable for any shares of, any class of its shares or other equity securities (“New Securities”), the Company shall first make an offering of such New Securities to each Material Holder in accordance with the
following provisions: 
 (a) The Company shall deliver a notice (“Notice”) to each of the Material
Holders stating (i) its bona fide intention to offer such New Securities, (ii) the number of such New Securities to be offered, and (iii) the price and a summary of the terms, if any, upon which it proposes to offer such New
Securities. Notice shall be provided in accordance with Section 5.5. 

  
 -21-

 (b) By written notification received by the Company within fifteen
(15) business days after receipt of the Notice, each Material Holder may elect to purchase or obtain, at the price and on the terms specified in the Notice, up to its Pro Rata Share of such New Securities. The Company shall promptly, in
writing, inform each Material Holder that elects to purchase all the New Securities available to it (a “Fully-Exercising Holder”) of any other Material Holder’s failure to do likewise. During the five (5) business day
period commencing after such information is given, each Fully-Exercising Holder may elect to purchase that portion of the New Securities for which Material Holders were entitled to subscribe but which were not subscribed for by the Material Holders
that equals the ratio that (i) the number of Ordinary Shares issuable or issued upon conversion of the Preference Shares held by such Material Holder bears to (ii) the total number of Ordinary Shares of the Company then held (assuming full
conversion and exercise of all convertible or exercisable securities, whether vested or unvested, then outstanding), by all Fully-Exercising Holders who wish to purchase some of the unsubscribed shares. 

(c) If all New Securities that the Material Holders are entitled to obtain pursuant to subsection 4.1(b) are not elected to be
obtained as provided in subsection 4.1(b) hereof, the Company may, during the ninety (90) day period following the expiration of the period provided in subsection 4.1(b) hereof, offer the remaining unsubscribed portion of such New
Securities to any person or persons at a price not less than, and upon terms no more favorable to the offeree than those specified in the Notice. If the Company does not enter into an agreement for the sale of the New Securities within such period,
or if such agreement is not consummated within sixty (60) days of the execution thereof, the right provided hereunder shall be deemed to be revived and such New Securities shall not be offered unless first reoffered to the Material Holders in
accordance herewith. 
 (d) The right of first offer in this Section 4.1 shall not be applicable to the Series B
Shares, the Series B-1 Shares, and any warrant (and any equity securities issued or issuable upon exercise of such warrant) issued prior to the date hereof, or Ordinary Shares (or any options, warrants or convertible securities exercisable or
convertible into Ordinary Shares) issued or issuable: 
 (i) upon conversion of Preference Shares; 

(ii) as a dividend or distribution on Ordinary Shares or Preference Shares; 

(iii) to employees, directors or consultants of the Company pursuant to option plans or other equity incentive arrangements
approved by the Board, provided that the aggregate number of such Ordinary Shares issued or deemed issued from time to time under this subsection (iii) does not at any time exceed 16,400,000 shares (as adjusted for Recapitalizations) in
the aggregate, inclusive of all such shares so issued (or deemed issued) prior to or after the date hereof, unless otherwise unanimously approved by the Board; 
 (iv) in connection with a Recapitalization; 

  
 -22-

 (v) pursuant to a joint venture arrangement or the acquisition of another entity or
business by the Company by merger, purchase of substantially all of the assets, acquisition of shares or other reorganization whereby the Company or its members own not less than a majority of the voting power of the surviving or successor entity,
provided that such joint venture arrangement or acquisition is approved by the Board; 
 (vi) as a result of the
application of the anti-dilution provisions set forth in Article 21 of the Articles; 
 (vii) with the approval of
holders of a majority of the outstanding Preference Shares, voting together as a single class; and 
 (viii) pursuant to
the terms of the B-1 Extension Purchase Agreement; and 
 (ix) to financial institutions or lessors in connection with
commercial credit arrangements, equipment financings or similar transactions approved by the Board. 
 (e) A Material
Holder’s rights under this Section 4.1 may be assigned to an Eligible Transferee in connection with the transfer of registration rights provided for in Section 2.13 above. 

4.2 Termination of Right. The right of first offer granted hereunder shall be terminated and be of no further force or
effect immediately prior to the earlier of (i) the effectiveness of an IPO (and such right shall not apply to any securities sold in connection with such IPO) and (ii) the effectiveness of a Deemed Liquidation Event. 

 

	 	5.	Miscellaneous. 

 5.1
Waivers and Amendments. 
 (a) Subject to Section 5.1(b), with the written consent of the Holders of a
majority of the Registrable Securities then outstanding, the obligations of the Company and the rights of the Investors under this Agreement may be waived (either generally or in a particular instance, either retroactively or prospectively and
either for a specified period of time or indefinitely), and with the same consent, the Company, when authorized by resolution of its Board, may enter into a supplementary agreement for the purpose of adding any provisions to or changing or waiving
in any manner or eliminating any of the provisions of this Agreement. Upon the effectuation of each such waiver, consent, agreement, amendment or modification the Company shall promptly give written notice thereof to any Party that has not
previously consented thereto in writing. All such waivers and amendments shall be binding on all parties to this Agreement. Neither this Agreement nor any provisions hereof may be changed, waived, discharged or terminated orally, but only by a
signed statement in writing. 
 (b) Notwithstanding Section 5.1(a), no obligation of the Company or right of the
Investors under this Agreement may be waived or amended without the prior written consent of the Holders of a majority of the Series B-1 Shares then outstanding if such waiver or amendment 

  
 -23-

 
would: (i) adversely affect the Holders of Series B-1 Shares in a materially disproportionate manner as compared with the Holders of Series A Shares, taking into account the Original Issue
Price of the Series B-1 Shares and the Original Issue Price of the Series A Shares, (ii) amend or waive the provisions set forth in Section 2.17 (Limitation on Subsequent Registration Rights) that the Company shall not enter into any
agreement with any holder or prospective holder of any securities of the Company or take any other action that would have the effect of negating or removing the registration rights of the Holders of Series B-1 Shares or would adversely affect the
Holders of Series B-1 Shares in a materially disproportionate manner as compared with the Holders of Series A Shares, taking into account the Original Issue Price of the Series B-1 Shares and the Original Issue Price of the Series A Shares,
(iii) amend or waive the provision set forth in Section 3.10 (Drag-Along Rights) that the aggregate consideration to be paid to the shareholders of the Company in a Deemed Liquidation Event, less any required withholding, holdbacks or
escrows, must not be less than $700,000,000 in order for such Deemed Liquidation Event to constitute an Approved Sale or (iv) amend or waive the provisions of Sections 3.11(a) through 3.11(d) (Protective Provisions). 

5.2 Governing Law. This Agreement shall be governed by, and construed and enforced in accordance with, the internal laws of
the State of California as such laws are applied to agreements between California residents entered into and to be performed within California. Each of the Parties irrevocably: (a) agrees that any dispute or controversy arising out of, relating
to, or concerning any interpretation, construction, performance or breach of this Agreement, shall be settled by arbitration to be held in Santa Clara County, California, in accordance with the rules then in effect of the American Arbitration
Association; (b) waives, to the fullest extent it may effectively do so, any objection which it may now or hereafter have to the laying of venue of any such arbitration; and (c) submits to the exclusive jurisdiction of the State of
California in any such arbitration. The Parties hereby acknowledge and agree that (i) any decision of the arbitrator shall be final, conclusive and binding on the parties to the arbitration; (ii) judgment may be entered on the
arbitrator’s decision in any court having jurisdiction; and (iii)the parties to the arbitration shall each pay an equal share of the costs and expenses of such arbitration, and each party shall separately pay for its respective counsel fees and
expenses; provided, however, that the prevailing party in any such arbitration shall be entitled to recover from the non-prevailing party its reasonable costs and attorney fees. 

5.3 Specific Enforcement. Except as otherwise provided herein, any and all remedies expressly conferred upon a Party by
this Agreement will be deemed cumulative with and not exclusive of any other remedy conferred hereby, or by law or equity upon such Party, and the exercise by a Party of any one remedy will not preclude the exercise of any other remedy. The Parties
agree that irreparable damage would occur in the event that any of the provisions of this Agreement were not performed in accordance with their specific terms or were otherwise breached. It is accordingly agreed that the Parties shall be entitled to
seek an injunction or injunctions to prevent breaches of this Agreement and to enforce specifically the terms and provisions hereof in any federal or state court in the State of California, this being in addition to any other remedy to which they
are entitled at law or in equity. 
 5.4 Successors and Assigns. Except as otherwise expressly provided herein,
the provisions hereof shall inure to the benefit of, and be binding upon, the successors, assigns, heirs, executors and administrators of the Parties. The Company shall not permit the transfer of any of the Registrable Securities on its books or
issue a new certificate representing any of the Registrable 

  
 -24-

 
Securities unless and until the person to whom such security is to be transferred shall have executed a written agreement, substantially in the form of this Agreement or a joinder agreement
approved by the Company, pursuant to which such person becomes a party to this Agreement and agrees to be bound by all the provisions hereof as if such person were an Investor. Any party who executes a joinder agreement with the Company in respect
of this Agreement shall, for all purposes, be deemed an “Investor” hereunder. 
 5.5 Notices. All
notices and other communications required or permitted hereunder shall be in writing and shall be sent by facsimile or mailed by electronic, registered or certified mail or by overnight courier or otherwise delivered by hand or by messenger,
addressed: 
 (a) if to an Investor, at the Investor’s address, as shown on Exhibit A or
Exhibit B hereto, or at such other address as the Investors shall have furnished to the Company in writing; 

(b) if to any other holder of any shares subject to this Agreement, at such address as such holder shall have furnished the
Company in writing, or, until any such holder so furnishes an address to the Company, then to and at the address of the last holder of such shares who has so furnished an address to the Company; or 

(c) if to the Company, at the address of the Company’s principal corporate offices to the attention of President, or at such
other address as the Company shall have furnished to the Investors in writing, 
 with a copy to: 

Carmen Chang 

Wilson Sonsini Goodrich & Rosati, P.C. 
 650 Page Mill Road 
 Palo Alto, CA 94304 

Facsimile: (650) 493-6811 
 Email: cchang@wsgr.com 
 Where a notice is sent by mail, service of the notice
shall be effected by properly addressing, pre-paying and mailing a letter containing the notice, and to have been effected at the expiration of three (3) business days after the letter containing the same is mailed as aforesaid. 

Where a notice is sent by overnight courier, service of the notice shall be effected by properly addressing, and sending such notice
through an internationally recognized express courier service, delivery fees pre-paid, and to have been effected three (3) business days following the day the same is sent as aforesaid. 

Where a notice is delivered by electronic mail, by hand or by messenger, service of the notice shall be deemed to be effected upon
delivery. 
 5.6 Severability of this Agreement. If one or more provisions of this Agreement are held to be
unenforceable under applicable law, the Parties agree to renegotiate such provision in good faith. In the event that the Parties cannot reach a mutually agreeable and enforceable 

  
 -25-

 
replacement for such provision, then (i) such provision shall be excluded from this Agreement, (ii) the balance of the Agreement shall be interpreted as if such provision were so
excluded and (iii) the balance of the Agreement shall be enforceable in accordance with its terms. 
 5.7
Information Confidential. Each Investor will hold in strict confidence and will not use, except for purposes of enforcing their rights under and making investment decisions relating to this Agreement, any confidential information about
the Company (which shall include, but is not limited to, any information provided to Investors pursuant to Sections 3.1 and 3.2 hereof) or its business received from the Company except information (i) which the Company authorizes the
Investors to use or disclose, (ii) which is known to the Investors prior to its disclosure by the Company, (iii) which is disclosed to the Investors by a third party without breach of any confidentiality obligation, (iv) which becomes
generally known in the industry through no fault of the Investors, or (v) which Investors are compelled by law to reveal. Investor will not use such information in violation of the Exchange Act or reproduce, disclose or disseminate such
information to any person, except as permitted herein. Any Investor which is a partnership shall be allowed to disclose confidential information received from the Company about the Company or its business to partners of such Investor provided
that such partners shall be subject to the restrictions set forth in this Section 5.7 and that the partnership shall be obligated to inform the partners of their individual obligations. 

5.8 Titles and Subtitles. The titles and subtitles used in this Agreement are used for convenience only and are not to be
considered in construing or interpreting this Agreement. 
 5.9 Counterparts; Telecopy Signatures. This Agreement
may be executed in counterparts, each of which shall be an original, and all of which together shall constitute one instrument. A facsimile, telecopy or other reproduction of this Agreement may be executed by one or more Parties, and an executed
copy of this Agreement may be delivered by one or more Parties by facsimile or similar electronic transmission device pursuant to which the signature of or on behalf of such Party can be seen, and such execution and delivery shall be considered
valid, binding and effective for all purposes. At the request of any Party, all Parties agree to execute an original of this Agreement as well as any facsimile, telecopy or other reproduction hereof. 

5.10 Delays or Omissions. No delay or omission to exercise any right, power or remedy accruing to any Party under this
Agreement, upon any breach or default of any other Party under this Agreement, shall impair any such right, power or remedy of such non-breaching or non-defaulting Party nor shall it be construed to be a waiver of any such breach or default, or an
acquiescence therein, or of or in any similar breach or default thereafter occurring; nor shall any waiver of any single breach or default be deemed a waiver of any other breach or default theretofore or thereafter occurring. Any waiver, permit,
consent or approval of any kind or character on the part of any Party of any breach or default under this Agreement, or any waiver on the part of any Party of any provisions or conditions of this Agreement, must be in writing and shall be effective
only to the extent specifically set forth in such writing. All remedies, either under this Agreement or by law otherwise affording to any Party, shall be cumulative and not alternative. 

5.11 Share Splits. All references to the number of shares in this Agreement shall be appropriately adjusted to reflect any
Recapitalization after the First Closing (as defined in the B-1 Extension Purchase Agreement). 

  
 -26-

 5.12 Aggregation of Shares. All Ordinary Shares and Preference Shares held or
acquired by any Holder and its affiliated entities or persons shall be aggregated together for the purpose of determining the availability of any rights under this Agreement. 
 5.13 Entire Agreement. This Agreement constitutes the full and entire understanding and agreement among the Parties to the subject matter hereof, and any and all other written or oral
agreements relating to the subject matter hereof existing between the Parties are expressly canceled. 
 5.14
Amendment and Restatement. The Prior Agreement is hereby superseded and amended in its entirety and restated in this Agreement. All provisions of, rights granted and covenants made in the Prior Agreement are hereby terminated,
waived, released and superseded in their entirety and shall have no further force or effect. 
 5.15 New
Investors. Notwithstanding anything herein to the contrary, if pursuant to an agreement (including the B-1 Extension Purchase Agreement, as may be amended time to time), additional parties may purchase Series B-1 Shares as
“Purchasers” thereunder, then each such Purchaser shall become a Party to this Agreement as an “Investor” hereunder, without the need for any consent, approval or signature of any Investor when such Purchaser has
both (i) purchased Series B-1 Shares under such agreement, and paid the Company all consideration payable for such shares and (ii) executed a copy of this Agreement as an “Investor.” 

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK] 

  
 -27-

 IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first above
written. 
  

	
	COMPANY:
	
	 SAGENT HOLDING CO.
 a
Cayman Islands exempted company

	
	By: /s/ Jeffrey
Yordon                                        

	Name: Jeffrey Yordon
	Title: President and Chief Executive Officer

 SIGNATURE PAGE TO SAGENT HOLDING CO. FOURTH AMENDED AND
RESTATED MEMBERS AGREEMENT 

 IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first above
written. 
  

	
	INVESTORS:
	
	VIVO VENTURES FUND CAYMAN V, L.P.
	
	By: Vivo Ventures Cayman V (GP), L.P.
	
	 By: Vivo Ventures Cayman V General Partner Limited,

its general partner

	
	By: /s/ Frank
Kung                                         
                       
	(signature)
	
	Name: Frank Kung
	Title: Director
	
	VIVO VENTURES V AFFILIATES FUND, L.P.
	
	By: /s/ Frank
Kung                                         
                       
	(signature)
	
	Name: Frank Kung
	Title: Managing Member of Vivo Ventures V, LLC, its General Partner

 SIGNATURE PAGE TO SAGENT HOLDING CO. FOURTH AMENDED AND
RESTATED MEMBERS AGREEMENT 

 IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first above
written. 
  

	
	INVESTORS:
	
	PACIFIC SEQUOIA HOLDINGS LLC
	
	By: /s/ John V.
Jonson                                        
        
	Name: John V. Jonson
	Title:   Manager

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED MEMBERS AGREEMENT 

 IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first above
written. 
  

	
	INVESTORS:
	
	THE SKOLL FOUNDATION
	
	By: /s/ John V.
Jonson                                        
        
	Name: John V. Jonson
	Title:   Manager

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED MEMBERS AGREEMENT 

 IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first above
written. 
  

	
	INVESTORS:
	
	THE SKOLL FUND
	
	By: /s/ John V.
Jonson                                        
        
	Name: John V. Jonson
	Title:   Manager

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED MEMBERS AGREEMENT 

 IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first above
written. 
  

	
	INVESTORS:
	
	WEYERHAEUSER COMPANY MASTER RETIREMENT TRUST
	Managed by Morgan Stanley Investment Management, Inc.
	
	By: The Bank of New York Mellon, not individually but solely in its capacity as Directed Trustee on behalf of the Trust
	
	By: /s/ Bernadette T.
Rist                                         
   
	Name: Bernadette T. Rist
	Authorized Signatory

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED MEMBERS AGREEMENT 

 IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first above
written. 
  

	
	INVESTORS:
	
	 SAILORSHELL & CO. FOR THE BENEFIT OF
 MORGAN STANLEY AIP GLOBAL
 DIVERSIFIED FUND LP

	
	 By: Morgan Stanley Alternative Investment
        Partners LP, its general partner

	By: Morgan Stanley AIP GP LP, its general partner
	 By: Morgan Stanley Alternative Investments Inc.,
        its general partner

	
	By:  /s/ James
Sperans                                        
        
	Name: James Sperans
	Title:   Managing Director
	
	 SAILORPIER & CO. FOR THE BENEFIT OF
 AURORA CAYMAN LIMITED

	
	 By: Morgan Stanley Investment Management Inc.,
        its investment manager

	
	By:  /s/ James
Sperans                                        
        
	Name: James Sperans
	Title:   Managing Director

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED MEMBERS AGREEMENT 

 IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first above
written. 
  

	
	INVESTORS:
	
	 STORMBAY & CO. FOR THE BENEFIT OF
 VIJVERPOORT HUIZEN C.V.

	
	 By: Morgan Stanley Alternative Investment
        Partners LP, its general partner

	By: Morgan Stanley AIP GP LP, its general partner
	 By: Morgan Stanley Alternative Investments Inc.,
        its general partner

	
	By: /s/ James
Sperans                                        
        
	Name: James Sperans
	Title:   Managing Director
	
	 STORMLAUNCH & CO. FOR THE BENEFIT
 OF MORGAN STANLEY PRIVATE MARKETS
 FUND III LP

	
	 By: Morgan Stanley Alternative Investment
        Partners LP, its general partner

	By: Morgan Stanley AIP GP LP, its general partner
	 By: Morgan Stanley Alternative Investments Inc.,
        its general partner

	
	By:  /s/ James
Sperans                                        
        
	Name: James Sperans
	Title:   Managing Director

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED MEMBERS AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	 STORMSTAR & CO. FOR THE BENEFIT OF
 MORGAN STANLEY PRIVATE MARKETS
 FUND EMPLOYEE INVESTORS III LP

	
	 By: Morgan Stanley Alternative Investment
        Partners LP, its general partner

	By: Morgan Stanley AIP GP LP, its general partner
	 By: Morgan Stanley Alternative Investments Inc.,
        its general partner

	
	By: /s/ James
Sperans                                        
            
	Name: James Sperans
	Title:   Managing Director
	
	NUCLEAR ELECTRIC INSURANCE LIMITED
	
	 By: Morgan Stanley Investment Management Inc.,
        its investment manager

	
	By: /s/ James
Sperans                                        
        
	Name: James Sperans
	Title:   Managing Director

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED MEMBERS AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	FACTORY MUTUAL INSURANCE COMPANY
	
	By:  /s/ Paul
LaFleche                                        
        
	Name: Paul LaFleche
	Title:  Senior Vice President of Investments

 SIGNATURE PAGE TO SAGENT HOLDING CO. FOURTH AMENDED AND
RESTATED MEMBERS AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	CNF INVESTMENTS II, LLC
	
	By: /s/ Robert J.
Flanagan                                        
    
	(signature)
	
	Name: Robert J. Flanagan
	Title: Manager

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED MEMBERS AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	VIVO VENTURES VI AFFILIATES FUND L.P.
	By: Vivo Ventures VI, LLC, its Managing Member
	
	By: /s/ Frank
Kung                                         
             
	(signature)
	
	Name: Frank Kung
	Title: General Partner
	
	VIVO VENTURES FUND CAYMAN VI, L.P.
	By: Vivo Venture Cayman VI (GP), L.P.
	 By: Vivo Ventures Cayman VI General Partner
        Limited, its general partner

	
	By: /s/ Frank
Kung                                         
             
	(signature)
	
	Name: Frank Kung
	Title: Director

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED MEMBERS AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	KEY GATE INVESTMENTS LIMITED
	
	By: /s/ Andrew
Lo                                         
               
	(signature)
	
	Name: Andrew Lo
	Title: Authorized Representative

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED MEMBERS AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	LINK BEST CAPITAL LIMITED
	
	By: /s/ Shing Chi
Yap                                         
         
	(signature)
	
	Name: Shing Chi Yap
	Title: Director

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED MEMBERS AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	WESTFIELD CAPITAL MANAGEMENT
	
	 By: Westfield Partners, L.L.C., its General Partner
 By: Westfield Capital Management Company, L.P.,
 it’s Manager

By: WMS General Partner, LLC, its General Partner

	
	By: /s/ William A.
Muggia                                        
  
	(signature)
	
	Name: William A. Muggia
	(print name)
	
	Title: Authorized Person

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED MEMBERS AGREEMENT 

 Exhibit A 

Existing Investors 

Vivo Ventures Fund Cayman VI, L.P. 
 575
High Street, Suite 201 
 Palo Alto, CA 94301 
 Attn: Chen Yu 
 Vivo Ventures Fund Cayman V, L.P. 

c/o Vivo Ventures V, LLC 
 575 High Street, Suite
201 
 Palo Alto, CA 94301 
 Attn: Chen
Yu 
 Vivo Ventures VI Affiliates Fund, L.P. 
 575 High Street, Suite 201 
 Palo Alto, CA 94301 

Attn: Chen Yu 
 Vivo Ventures V Affiliates
Fund, L.P. 
 c/o Vivo Ventures V, LLC 
 575 High Street, Suite 201 
 Palo Alto, CA 94301 

Attn: Chen Yu 
 Stormlaunch & Co.
for the Benefit of Morgan Stanley Private Markets Fund III LP 
 c/o Morgan Stanley Alternative Investments Inc. 

100 Front Street, Suite 400 
 West Conshohocken,
Pennsylvania 19428-2881 
 Attn: Matthew Allen, Executive Director 
 Stormstar & Co. for the Benefit of Morgan Stanley Private Markets Fund Employee Investors III LP 
 c/o Morgan Stanley Alternative Investments Inc. 
 100 Front Street, Suite 400 

West Conshohocken, Pennsylvania 19428-2881 

Attn: Matthew Allen, Executive Director 
 CNF
Investments II, LLC 
 7500 Old Georgetown Road 
 Bethesda, MD 20814 
 Attn: Robert Flanagan 

Weyerhaeuser Company Master Retirement Trust 
 Legal Department 
 500 Grant Street 
 BNY Mellon Center 
 AIM: 151-1935 
 Pittsburgh, Pennsylvania 15258-0001 
 Attn: Bernadette Rist 

 Sailorshell & Co. for the benefit of Morgan Stanley AIP Global Diversified Fund LP

 100 Front Street, Suite 400 

West Conshohocken, Pennsylvania 19428-2881 

Attn: Matthew Allen, Executive Director 

Dohmen Investment Group, LLC 
 215 North
Water Street 
 Milwaukee, WI 53202 

Attn: John Vaughan, Chief Financial Officer 

Pacific Sequoia Holdings LLC 
 c/o Capricorn Management, LLC 
 250 University Avenue, Suite 300 

Palo Alto, CA 94301 
 Attn: John Johnson 
 c/o Mellon Global Securities Services 

135 Santilli Highway 
 026-0035 
 Everett, MA 02149 

Attn: Nicole Strazzulla 
 c/o Seiler & Company 
 1100 Marshall Street 

Redwood City, CA 94063 
 Attn: James G. B. DeMartini III, CPA 
 Stormbay & Co. for the benefit of Vijverpoort
Huizen C.V. 
 100 Front Street, Suite 400 
 West Conshohocken, Pennsylvania 19428-2881 
 Attn: Matthew Allen, Executive Director 

Sailorpier & Co. for the benefit of Aurora Cayman Limited 
 100 Front Street, Suite 400 
 West Conshohocken, Pennsylvania 19428-2881 

Attn: Matthew Allen, Executive Director 
 The
Skoll Foundation 
 c/o Capricorn Management, LLC 
 250 University Avenue, Suite 300 
 Palo Alto, CA 94301 

Attn: John Johnson 
 c/o Mellon Global Securities Services 
 135 Santilli Highway 

026-0035 

Everett, MA 02149 

Attn: Nicole Strazzulla 
 c/o Seiler & Company 
 1100 Marshall Street 

Redwood City, CA 94063 
 Attn: James G. B. DeMartini III, CPA 

 The Skoll Fund 
 c/o Capricorn Management, LLC 
 250 University Avenue, Suite 300 

Palo Alto, CA 94301 
 Attn: John Johnson 
 c/o Mellon Global Securities Services 

135 Santilli Highway 
 026-0035 
 Everett, MA 02149 

Attn: Nicole Strazzulla 
 c/o Seiler & Company 
 1100 Marshall Street 

Redwood City, CA 94063 
 Attn: James G. B. DeMartini III, CPA 
 Factory Mutual Insurance Company 

225 Wyman Street 
 Waltham, MA 02454 

Attn: Paul LaFleche, Senior Vice President of Investments 
 Nuclear Electric Insurance Limited 
 1201 North Market Street, 11th Floor 

Wilmington, DE 19801 
 Attn: Robert MacGovern,
Vice President - Investments 
 CIBC WMC, Inc. 
 425 Lexington Ave. 
 New York, NY 10017 
 Attn: Kathryn Casparian 
 Zhejiang Hisun Pharmaceutical Co., Ltd. 

Key Gate Investments Limited 
 China
Renaissance Capital Investment 
 Suite 305 St. George’s Building 
 2 Ice House Street 
 Central, Hong Kong 
 Hong Kong SAR 
 Attn: Andrew Lo 

 Exhibit B 

New Investors 
 Link
Best Capital Limited 
 Room 2201, 22/F., Far East Consortium Building 
 121, Des Voeux Road, 
 Central, Hong Kong. 
 Attn: Yap Shing Chi 
 Westfield Capital Management 

One Financial Center, 24th Floor 

Boston, MA 02111-2621 
 Attn: Matthew Strobeck

 Exhibit C 

Form of Confidential Information 
 and Invention Assignment Agreement 

 Exhibit D 

Form of PFIC Annual Information StatementThird Amended and Restated Right of First Refusal and Co-Sale Agreement

 Exhibit 10.9 
 SAGENT HOLDING CO. 
 THIRD AMENDED AND RESTATED RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 
 This Third Amended and Restated Right of First Refusal and Co-Sale Agreement (the
“Agreement”) is made and entered into as of September 3, 2010 by and among Sagent Holding Co., a Cayman Islands exempted company (the “Company”), each of the members listed on Exhibit A attached hereto
(the “Existing Investors”), each of the members listed on Exhibit B attached hereto (the “Key Shareholders”), each of the members listed on Exhibit C attached hereto (the “New
Investors”, and together with the Existing Investors, the “Investors”). 
 RECITALS 

A. The Key Shareholders currently own Ordinary Shares (the “Ordinary Shares”) and/or Series A Preference Shares (the
“Series A Shares”) of the Company. 
 B. Each Existing Investor holds shares of Series A Shares and/or Series
B-1 Preference Shares (the “Series B-1 Shares”) of the Company and possesses the rights of first refusal and co-sale pursuant to the Company’s Second Amended and Restated Right of First Refusal and Co-Sale Agreement, dated
April 6, 2010 (the “Prior Agreement”). 
 C. The Company is issuing to the New Investors additional
Series B-1 Shares pursuant to the Series B-1 Extension Preference Purchase Agreement dated as of April 6, 2010 (the “B-1 Extension Purchase Agreement”). 
 D. It is a condition to the closing of the sale of the additional Series B-1 Shares to the New Investors pursuant to the B-1 Extension Purchase Agreement that the Company, the Investors and Key
Shareholders enter into this Agreement. 
 E. The Company, certain Key Shareholders and the Existing Investors desire to amend
and restate the Prior Agreement in its entirety as set forth herein and to accept the rights and obligations created pursuant hereto in lieu of their rights and obligations under the Prior Agreement. 

AGREEMENT 

NOW, THEREFORE, in consideration of the foregoing premises and certain other good and valuable consideration, the receipt and sufficiency
of which are hereby acknowledged, the parties hereto (each, a “Party” and collectively, the “Parties”) agree as follows: 

 1. Certain Definitions. For purposes of this Agreement, the following terms
have the following meanings: 
 (a) “Articles” means the Company’s Sixth Amended and Restated Articles of
Association, as amended from time to time. 
 (b) “Co-Sale Eligible Investors” shall mean Investors who or
which, along with the Investors’ affiliates, related individuals or entities, at the time in question, hold at least five hundred thousand (500,000) Series A Shares or Series B-1 Shares or a combination thereof (as may be adjusted from
time to time for Recapitalizations). 
 (c) “Days” means calendar days. 

(d) “Deemed Liquidation Event” has the meaning given such term in the Articles. 

(e) “Eligible Investors” shall mean the Co-Sale Eligible Investors and ROFR Eligible Investors. 

(f) “Pro Rata Co-Sale Share” means, as to each Co-Sale Eligible Investor’s Right of Co-Sale, the percentage
determined by dividing (i) the number of Series A Shares and Series B-1 Shares held by the Co-Sale Eligible Investor on an as-converted basis, by (ii) the total number of Shares held by the Seller and all Selling Investors (as
defined in Section 4(a)) on an as-converted basis. 
 (g) “Pro Rata ROFR Share” means, as to each ROFR
Eligible Investor’s Right of First Refusal, the percentage determined by dividing (i) the number of Series A Shares and Series B-1 Shares held by the ROFR Eligible Investor on an as-converted basis on the date of the Transfer Notice (as
defined in Section 2(b)), by (ii) the total number of Shares held by all Participating Investors exercising their Right of First Refusal as of such date. 
 (h) “Recapitalization” means any share split, share dividend, share combination or consolidation, recapitalization, reclassification or other similar event in relation to the shares of
the Company. 
 (i) “Right of Co-Sale” means the right of Co-Sale provided to the Co-Sale Eligible Investors in
Section 4 of this Agreement. 
 (j) “Right of First Refusal” means the right of first refusal provided to
the Company and the ROFR Eligible Investors in Section 3 of this Agreement. 
 (k) “ROFR Eligible
Investors” shall mean Investors who or which, along with the Investors’ affiliates, related individuals or entities, at the time in question, hold at least five hundred thousand (500,000) Series A Shares or Series B-1 Shares or a
combination thereof (as may be adjusted from time to time for Recapitalizations). 
 (l) “Seller” means any Key
Shareholder proposing to Transfer Shares. 

  
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 (m) “Shares” means all Ordinary Shares, Series A Shares and Series B-1
Shares and for purposes of this Agreement, excludes Series B Preference Shares of the Company. 
 (n)
“Transfer” means and includes any sale, assignment, encumbrance, hypothecation, pledge, conveyance in trust, gift, transfer by bequest, devise or descent, or other transfer or disposition of any kind, including but not limited to
transfers to receivers, levying creditors, trustees or receivers in bankruptcy proceedings or general assignees for the benefit of creditors, whether voluntary or by operation of law, directly or indirectly, except: 

(i) any transfers of Shares by a Seller to the Seller’s spouse, siblings, parents, lineal descendants or antecedents or trusts for
the benefit of the Seller or the Seller’s spouse, siblings, parents or lineal descendants or antecedents or transfers of Shares by the Seller by devise or descent; provided that, in all cases, the transferee or other recipient executes a
counterpart copy of this Agreement and becomes bound thereby as was the Seller; provided further that, if such transfer is to a trust, such trust must agree that no person shall become a beneficiary of such trust other than the persons
identified in this Section 1(n)(i); 
 (ii) on a cumulative basis, transfers of up to five percent (5%) of Shares (as
may be adjusted from time to time for Recapitalizations) held by any Seller as measured from the date hereof for the period of this Agreement; provided, that, in all cases, the transferee executes a counterpart copy of this Agreement
and becomes bound thereby as was the Seller; 
 (iii) any bona fide gift, provided that the transferee or donee or other
recipient executes a counterpart copy of this Agreement and becomes bound thereby as was the Seller; 
 (iv) any bona fide
pledge made pursuant to a bona fide loan transaction that creates a mere security interest, if the pledgee executes a counterpart copy of this Agreement and becomes bound thereby as a Seller in the event that and to the extent that such pledgee ever
acquires ownership of such shares; 
 (v) any transfers in a public offering pursuant to (a) the Securities Act of 1933,
as amended (the “Securities Act”), or (b) the securities laws applicable to an offering of securities in a jurisdiction other than the United States; 
 (vi) any transfer to the Company or a ROFR Eligible Investor pursuant to the terms of this Agreement; or 
 (vii) any repurchase of the Seller Shares by the Company pursuant to agreements under which the Company has the option to repurchase such Seller Shares upon the occurrence of certain events, such as
termination of employment, or in connection with the exercise by the Company of any rights of first refusal. 
 2.
Restrictions on Transfer. 
 (a) General. Before any Seller may Transfer any Shares, the Company or its
assignee(s) and the Eligible Investors shall have a Right of First Refusal and/or Right of Co-Sale upon the terms and conditions set forth herein. 

  
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 (b) Notice of Proposed Transfer. Prior to the Seller Transferring any of his, her, or
its Shares, the Seller shall deliver to the Company and the Eligible Investors a written notice (the “Transfer Notice”) stating: (i) the Seller’s bona fide intention to sell or otherwise Transfer such Shares (such Shares,
the “Offered Shares”); (ii) the name, address and phone number of each proposed purchaser or other transferee (“Proposed Transferee”); (iii) the aggregate number of Offered Shares to be Transferred to each
Proposed Transferee; (iv) the bona fide cash price or other consideration for which the Seller proposes to Transfer the Offered Shares (the “Offered Price”) and the other material terms of such proposed Transfer; (v) each
Eligible Investor’s right to exercise its Right of First Refusal and/or its Right of Co-Sale (but not both rights) with respect to the Offered Shares; and (vi) a deadline, consistent with the terms of this Agreement, within which the
Company and Eligible Investors must exercise such rights. 
 3. Right of First Refusal. 

(a) Exercise by the Company. The Company has a Right of First Refusal to purchase all or any part of the Offered Shares, provided
that the Company gives written notice of the exercise of such right to the Seller within thirty (30) days (the “Initial Refusal Period”) after the last date on which the Transfer Notice is, pursuant to Section 9(a) hereof,
deemed to be effective as to the Company and all Eligible Investors. 
 (b) Initial Exercise by the ROFR Eligible
Investors. Subject to the limitations of this Section 3(b), concurrently with the Company, the ROFR Eligible Investors and their affiliated assignees (any affiliate, partner, retired partner, member, retired member, family member, or trust,
either with respect to a particular exercise of rights or as a transferee of Shares previously held by a ROFR Eligible Investor) have a Right of First Refusal to purchase all or any part of the Offered Shares; provided that each ROFR Eligible
Investor so electing gives written notice of the exercise of such right to the Seller within the Initial Refusal Period. Such notice by each ROFR Eligible Investor shall state the maximum number of Offered Shares such ROFR Eligible Investor commits
to purchase pursuant to the terms of this Section 3. Upon the earlier to occur of (i) the termination of the Initial Refusal Period or (ii) the time when the Seller has received written confirmation from the Company regarding its
exercise of its Right First Refusal, the Company shall be deemed to have made its election with respect to the Offered Shares, and the shares for which the ROFR Eligible Investors may exercise their Rights of First Refusal shall be correspondingly
reduced to the extent the Company elects to purchase all or any part of the Offered Shares. To the extent that the Company elects not to purchase all of the Offered Shares, such remaining shares shall be allocated to the ROFR Eligible Investors (the
“Remaining Shares”) who have given written notice of their exercise of such right within the Initial Refusal Period (the “Participating Investors”). To the extent that the aggregate number of shares that the
Participating Investors desire to purchase exceeds the Remaining Shares, each Participating Investor will be entitled to purchase its Pro Rata ROFR Share of the Remaining Shares. Any Remaining Shares not allocated to Participating Investors pursuant
to the immediately preceding sentence shall be reallocated to those Participating Investors who fully exercised their Right of First Refusal (“Fully Exercising Investors”). Such reallocation among Fully Exercising Investors shall be
on the same basis as the initial allocation, excluding from the denominator for each relevant calculation Participating Investors who are not Fully Exercising Investors. Within five (5) days after the expiration of the Initial Refusal Period,
the Seller will give written notice to the Company and each ROFR Eligible Investor specifying the number of Offered Shares that was subscribed by the Company and the Participating Investors (the “Confirmation Notice”). The
Confirmation Notice shall specify the number of shares to be purchased by the Company and the Participating Investors. It shall also specify the number of shares not purchased, if any, under Sections 3(a) and 3(b) hereof. 

  
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 (c) Purchase Price. The purchase price for the Offered Shares to be purchased by the
Company or by a Participating Investor under this Agreement will be the Offered Price, and will be payable as set forth in Section 3(d) hereof. If the Offered Price includes consideration other than cash, the cash equivalent value of the
non-cash consideration will be determined by the Board of Directors of the Company in good faith, which determination will be binding upon the Company, each Participating Investor and the Seller, absent fraud or error. All other material terms of
such sale will be those set forth in the Transfer Notice. 
 (d) Payment. Payment of the purchase price for the Offered
Shares purchased by the Company or by a Participating Investor will be made within fifteen (15) days after the delivery of the Confirmation Notice. Payment of the purchase price will be made, at the option of the Company or the Participating
Investor, (i) in cash (or by check), (ii) by cancellation of all or a portion of any outstanding indebtedness of the Seller to the Company or the Participating Investor, as the case may be, or (iii) by any combination of the
foregoing. 
 (e) Rights as a Member. If the Company or any ROFR Eligible Investor exercises its Right of First Refusal
to purchase all or any part of the Offered Shares, then, upon the date that the notice of such exercise by the Company or any ROFR Eligible Investor is deemed to be effective as to the Seller pursuant to Section 9(a) hereof (the
“Transfer Date”), the Seller will have no further rights as a holder with respect to such Offered Shares except the right to receive payment for such Offered Shares from the Company or the ROFR Eligible Investor(s), as the case may
be, in accordance with the terms of this Agreement. The Seller will forthwith cause all certificate(s) evidencing such Offered Shares to be surrendered for transfer to the Company or the ROFR Eligible Investor, as the case may be, and in the case of
a Transfer of Offered Shares to a ROFR Eligible Investor, upon payment of the purchase price for such shares by such ROFR Eligible Investor, the Company will register such ROFR Eligible Investor in the Company’s register of members as the
holder with respect to such Offered Shares. Following the Transfer Date, and until such time as the Company registers the ROFR Eligible Investor in the Company’s register of members in accordance with the preceding sentence, the Seller shall
vote its Offered Shares which such ROFR Eligible Investor is exercising its right to purchase as directed by such ROFR Eligible Investor and hold any dividends or other distributions on such Offered Shares received after the Transfer Date for the
benefit of such ROFR Eligible Investor to be paid to such ROFR Eligible Investor upon payment by ROFR Eligible Investor of the purchase price for such Offered Shares. 
 (f) Sellers’ Right to Transfer. If the Company and the ROFR Eligible Investors have not elected to purchase all or any portion of the Offered Shares, then the Seller may Transfer such portion
of the Offered Shares which the Company and, if applicable, the ROFR Eligible Investors have not elected to purchase to any Proposed Transferee named in the Transfer Notice, at the Offered Price or at a higher price; provided that such
Transfer shall still be subject to the Co-Sale Eligible Investors’ Right of Co-Sale as defined in Section 4 hereof and the Seller shall not enter into a binding agreement to sell any Offered Shares until all of the provisions of
Section 4(a) have been complied with; provided further that any such Transfer (i) is consummated within ninety (90) days after the end of the Initial Refusal Period, (ii) is on terms no more favorable to the Proposed

  
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Transferee than the terms proposed in the Transfer Notice, and (iii) is in accordance with all the terms of this Agreement. If the Offered Shares are not so Transferred during such ninety
(90) day period, then the Seller may not Transfer any of such Offered Shares without complying again in full with the provisions of this Section 3. 
 4. Right of Co-Sale. 
 (a) Initial Exercise by the Eligible
Investors. To the extent that the Company and the ROFR Eligible Investors do not exercise their respective Rights of First Refusal in full with respect to all of the Offered Shares pursuant to Section 3 hereof (i.e., Seller has a right to
transfer pursuant to Section 3(f)), then the Seller shall not enter into a binding agreement to sell any Offered Shares until all of the provisions of this Section 4(a) have been complied with. Each Eligible Investor who has not exercised
its right in Section 3(b) (a “Co-Sale Investor”) that notifies Seller in writing within seven (7) days after the delivery of the Confirmation Notice, as applicable (the “Initial Co-Sale Period”),
shall have the right to participate in such sale of shares (the “Co-Sale Eligible Shares”) on the same terms and conditions as specified in the Transfer Notice subject to the terms of this Section 4. Each Co-Sale Investor who
delivers a notice pursuant to the preceding sentence (a “Selling Investor”) may sell, pursuant to the Selling Investor’s Right of Co-Sale, up to that number of Shares held by such Selling Investor equal to the product of the
Co-Sale Eligible Shares multiplied by such Selling Investor’s Pro Rata Share. The Selling Investor shall indicate the number of Shares it then holds that it wishes to sell pursuant to this Section 4(a) (the “Selling Investor
Shares”). If, after the end of the Initial Co-Sale Period, any Co-Sale Investors decline to participate in sales under this Section 4 or do not fully exercise their full Right of Co-Sale, then, within two (2) days after the
Initial Co-Sale Period, the Seller will notify the Selling Investors who fully exercised their Right of Co-Sale pursuant to this Section 4(a) (“Fully Exercising Co-Sale Investors”) of the extent to which other Co-Sale Investors
declined to exercise their Right of Co-Sale (the “Co-Sale Notice”). The Fully Exercising Co-Sale Investors shall within five (5) days after the later of (i) the end of the Initial Co-Sale Period and (ii) the delivery
of the Co-Sale Notice as deemed to be effective in accordance with Section 9(a) hereof (the “Subsequent Co-Sale Period”), notify Seller of the number of additional Shares held by such Fully Exercising Co-Sale Investor that such
Selling Investor wishes to sell. If such requests are over-subscribed, the Fully Exercising Co-Sale Investors shall be cut back, pro rata, based on the Shares held (on an as-converted basis). The sale of the Selling Investor Shares shall
occur within twenty-five (25) days from the beginning of the Initial Co-Sale Period (the “Closing”). This Right of Co-Sale shall not apply with respect to Offered Shares sold or to be sold to ROFR Eligible Investors or the
Company under the Right of First Refusal. 
 (b) Consummation of Co-Sale. A Selling Investor may exercise the Right of
Co-Sale by delivering to the Seller at or before the Closing, one or more certificates, properly endorsed for Transfer, representing a number of shares not to exceed the number of shares to which Selling Investor is entitled in Section 4(a),
representing such Shares to be Transferred by the Seller on behalf of the Selling Investor. If the Selling Investor does not hold a certificate in that series, class or type of shares representing the number of securities owned and to be sold by
such Selling Investor pursuant to this Section 4, then the Company shall promptly issue a certificate representing the proper number of shares to be sold pursuant to this Right of Co-Sale. Following the Closing, the Company shall deliver a
certificate for the remaining balance of the securities held by the Selling Investor, if any, to such Selling Investor. At the Closing, such certificates or other instruments will 

  
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be transferred and delivered to the Transferee as set forth in the Transfer Notice in consummation of the Transfer of the Offered Shares pursuant to the terms and conditions specified in the
Transfer Notice, and the Seller will remit, or will cause to be remitted, to each Selling Investor, within ten (10) days after such Closing, that portion of the proceeds of the Transfer to which each Selling Investor is entitled by reason of
each Selling Investor’s participation in such Transfer pursuant to the Right of Co-Sale. 
 5. Multiple Series, Class
or Type of Shares. If the Offered Shares consists of more than one series, class or type of Shares, the Seller has the right to Transfer hereunder each such series, class or type; provided that if, as to the Right of Co-Sale, a
Selling Investor does not hold any of such series, class or type, and the Proposed Transferee is not willing, at the Closing, to purchase some other series, class or type of Shares from such Selling Investor, or is unwilling to purchase any Shares
from such Selling Investor at the Closing, then such Selling Investor will have the put right (the “Put Right”) set forth in Section 6(b) hereof. 
 6. Refusal to Transfer; Put Right. 
 (a) Refusal to Transfer.
Any attempt by any Seller to Transfer any Shares in violation of any provision of this Agreement will be void. The Company will not be required (i) to transfer on its books any Shares that have been sold, gifted or otherwise Transferred in
violation of this Agreement, or (ii) to treat as owner of such Shares, or to accord the right to vote or pay dividends to any purchaser, donee or other transferee to whom such Shares may have been so Transferred. 

(b) Put Right. If a Seller Transfers any Shares in contravention of the Co-Sale Eligible Investors’ Right of Co-Sale under
this Agreement (a “Prohibited Transfer”), or if the Proposed Transferee of Offered Shares desires to purchase a class, series or type of shares offered by the Seller but not held by a Co-Sale Eligible Investor or the Proposed
Transferee is unwilling to purchase any Shares from a Co-Sale Eligible Investor, such Co-Sale Eligible Investor may, by delivery of written notice to such Seller (a “Put Notice”) within ten (10) days after the later of
(i) the Closing as defined in Section 4(a) above, or (ii) the date on which such Co-Sale Eligible Investor becomes aware of the Prohibited Transfer or the terms thereof, require such Seller to purchase from such Co-Sale Eligible
Investor, for cash or such other consideration as the Seller received in the Prohibited Transfer or at the Closing, a number of Shares (of the same class or type as Transferred in the Prohibited Transfer or at the Closing if such Co-Sale Eligible
Investor then owns Shares of such class or type; otherwise Series A Shares, Series B-1 Shares or Ordinary Shares) having a purchase price (on an as-converted basis) equal to the aggregate purchase price that the Co-Sale Eligible Investor would have
received in the closing of such Prohibited Transfer if such Co-Sale Eligible Investor had elected to exercise its Right of Co-Sale with respect thereto or in the Closing if the Proposed Transferee had been willing to purchase the Shares of the
Co-Sale Eligible Investor (the “Put Shares”). The closing of such sale to the Seller will occur within ten (10) days after the date of such Co-Sale Eligible Investor’s Put Notice to such Seller. Upon the closing of the
transaction contemplated by the Put Notice, Seller shall also reimburse the Co-Sale Eligible Investor for any and all fees and expenses, including, but not limited to, legal fees and expenses, incurred pursuant to the exercise or attempted exercise
of such Co-Sale Eligible Investor’s Rights of Co-Sale pursuant to Section 4 or in the exercise of its rights under this Section 6 with respect to the Put Shares. 

  
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 7. Restrictive Legend and Stop-Transfer Orders. 

(a) Legend. The Key Shareholders understand and agree that the Company will cause the legend set forth below, or a legend
substantially equivalent thereto, to be placed upon any certificate(s) or other documents or instruments evidencing ownership of Shares by each Key Shareholder: 
 “THE SHARES REPRESENTED BY THIS CERTIFICATE ARE SUBJECT TO AND MAY ONLY BE SOLD, DISPOSED OF OR OTHERWISE TRANSFERRED IN COMPLIANCE WITH CERTAIN RIGHTS OF FIRST REFUSAL AND RIGHTS OF CO-SALE AS SET
FORTH IN A RIGHT OF FIRST REFUSAL AND CO-SALE AGREEMENT ENTERED INTO BY THE HOLDER OF THESE SHARES, THE COMPANY AND CERTAIN MEMBERS OF THE COMPANY. A COPY OF SUCH AGREEMENT IS ON FILE AT THE PRINCIPAL OFFICE OF THE COMPANY. SUCH RIGHTS OF FIRST
REFUSAL AND RIGHTS OF CO-SALE ARE BINDING ON TRANSFEREES OF THESE SHARES.” 
 (b) Stop Transfer Instructions. In
order to ensure compliance with the restrictions referred to herein, each Seller agrees that the Company may issue appropriate “stop transfer” certificates or instructions. 

(c) Transfers. No securities shall be Transferred unless (i) such Transfer is made in compliance with applicable federal and
state securities laws and (ii) prior to such Transfer, the transferee or transferees, who prior to such Transfer are not already parties to this Agreement, sign a counterpart to this Agreement pursuant to which it or they agree to be bound by
the terms of this Agreement. 
 8. Termination. This Agreement shall terminate and be of no further force or
effect upon the earlier to occur of: (a) the effectiveness of the registration statement for the Company’s first firm commitment underwritten public offering registered under the Securities Act, or pursuant to the securities laws
applicable to an offering of securities in another jurisdiction pursuant to which such securities will be listed on an internationally-recognized securities exchange; or (b) the effectiveness of a Deemed Liquidation Event. 

9. Miscellaneous Provisions. 
 (a) Notices. All notices and other communications required or permitted hereunder shall be in writing and shall be sent by facsimile or mailed by electronic, registered or certified mail or by
overnight courier or otherwise delivered by hand or by messenger, addressed: 
 (i) if to an Investor, at the Investor’s
address, as shown on Exhibit A or Exhibit C hereto, or at such other address as the Investor shall have furnished to the Company and the Key Shareholders in writing; 

(ii) if to the Key Shareholders, at the Key Shareholders’ address, as shown on Exhibit B hereto, or at such other
address as the Key Shareholders shall have furnished to the Company and Investors in writing; and 

  
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 (iii) if to the Company, at the address of the Company’s principal corporate offices
to the attention of President, or at such other address as the Company shall have furnished to the Purchasers and the Key Shareholders in writing, 
 with a copy to: 
 Carmen Chang 

Wilson Sonsini Goodrich & Rosati, P.C. 
 650 Page Mill Road 
 Palo Alto, CA 94304 

Facsimile: (650) 493-6811 
 Email: cchang@wsgr.com 
 Where a notice is sent by mail, service of the notice
shall be effected by properly addressing, pre-paying and mailing a letter containing the notice, and to have been effected at the expiration of three (3) business days after the letter containing the same is mailed as aforesaid. 

Where a notice is sent by overnight courier, service of the notice shall be effected by properly addressing, and sending such notice
through an internationally recognized express courier service, delivery fees pre-paid, and to have been effected three (3) business days following the day the same is sent as aforesaid. 

Where a notice is delivered by electronic mail, by hand or by messenger, service of the notice shall be deemed to be effected upon
delivery. 
 (b) Successors and Assigns. Except as otherwise expressly provided herein, the provisions hereof shall inure
to the benefit of, and be binding upon, the successors, assigns, heirs, executors and administrators of the parties hereto. 

(c) Severability. If one or more provisions of this Agreement are held to be unenforceable under applicable law, the parties agree
to renegotiate such provision in good faith. In the event that the parties cannot reach a mutually agreeable and enforceable replacement for such provision, then (i) such provision shall be excluded from this Agreement, (ii) the balance of
the Agreement shall be interpreted as if such provision were so excluded, and (iii) the balance of the Agreement shall be enforceable in accordance with its terms. 
 (d) Waivers and Amendment. Subject to Section 9(n), with the written consent of Investors holding at least a majority of the then outstanding Series A Shares and Series B-1 Shares (voting
together as a single class on an as-converted basis), the obligations of the Company, the Key Shareholders and the rights of the Eligible Investors under this Agreement may be waived (either generally or in a particular instance, either
retroactively or prospectively and either for a specified period of time or indefinitely), and with the same consent the Company, when authorized by resolution of its Board of Directors, may enter into a supplementary agreement for the purpose of
adding any provisions to or changing or waiving in any manner or eliminating any of the provisions of this Agreement, provided, however, that any amendment, waiver, discharge or termination that, by its terms, adversely affects the
rights of the Key Shareholders hereunder in a materially disproportionate manner shall not be effective unless approved by the Key Shareholders; provided, 

  
 -9-

 
further, that any amendment, waiver, discharge or termination that, by its terms, adversely affects the rights of the holders of Series B-1 Shares in a materially disproportionate manner
shall not be effective unless approved by the holders of a majority of the Series B-1 Shares; provided, further, that for the purposes of this Section 9(d), the amendment of Sections 1(b) or 1(k) to alter the respective
shareholding threshold numbers set forth therein or the amendment of Sections 1(f) or 1(g) in a manner adverse to the holders of Series B-1 Shares shall be deemed materially adverse to and require the approval of the holders of a majority of the
Series B-1 Shares. For avoidance of doubt, the Company and Investors holding at least a majority of the then outstanding Series A Shares and Series B-1 Shares (voting as a single class) may, without the consent of the Key Shareholders, amend this
Agreement to add new Key Shareholders or other Investors and to provide that securities held by such persons will be bound by the terms hereof. Upon the effectuation of each such waiver, consent, agreement, amendment or modification the Company
shall promptly give written notice thereof to the record holders of the Series A Shares and/or the Series B-1 Shares who have not previously consented thereto in writing. Neither this Agreement nor any provisions hereof may be changed, waived,
discharged or terminated orally, except by a signed statement in writing. 
 (e) Continuity of Other Restrictions. Any
Shares not purchased by the Company or any ROFR Eligible Investor under their Right of First Refusal hereunder will continue to be subject to all other restrictions imposed upon such Shares by law, including any restrictions imposed under the
Articles. 
 (f) Governing Law. This Agreement shall be governed by, and construed and enforced in accordance with, the
internal laws of the State of California as such laws are applied to agreements between California residents entered into and to be performed within California. Each of the Parties irrevocably: (a) agrees that any dispute or controversy arising
out of, relating to, or concerning any interpretation, construction, performance or breach of this Agreement, shall be settled by arbitration to be held in the State of California, in accordance with the rules then in effect of the American
Arbitration Association; (b) waives, to the fullest extent it may effectively do so, any objection which it may now or hereafter have to the laying of venue of any such arbitration; and (c) submits to the exclusive jurisdiction of the
State of California in any such arbitration. The Parties hereby acknowledge and agree that (a) any decision of the arbitrator shall be final, conclusive and binding on the parties to the arbitration; (b) judgment may be entered on the
arbitrator’s decision in any court having jurisdiction; and (c) the parties to the arbitration shall each pay an equal share of the costs and expenses of such arbitration, and each such party shall separately pay for its respective counsel
fees and expenses; provided, however, that the prevailing party in any such arbitration shall be entitled to recover from the non-prevailing party its reasonable costs and attorney fees. 

(g) Specific Enforcement. Except as otherwise provided herein, any and all remedies expressly conferred upon a party by this
Agreement will be deemed cumulative with and not exclusive of any other remedy conferred hereby, or by law or equity upon such party, and the exercise by a party of any one remedy will not preclude the exercise of any other remedy. The parties
hereto agree that irreparable damage would occur in the event that any of the provisions of this Agreement were not performed in accordance with their specific terms or were otherwise breached. It is accordingly agreed that the parties shall be
entitled to seek an injunction or injunctions to prevent breaches of this Agreement and to enforce specifically the terms and provisions hereof in any federal or state court in the State of California, this being in addition to any other remedy to
which they are entitled at law or in equity. 

  
 -10-

 (h) Obligations of Company; Binding Nature of Exercise. The Company agrees to use its
commercially reasonable efforts to enforce the terms of this Agreement, to inform the Eligible Investors of any breach hereof (to the extent the Company has knowledge thereof) and to assist the Eligible Investors in the exercise of their rights and
the performance of its obligations hereunder. Any exercise of the Right of First Refusal or Right of Co-Sale will be binding upon the party so exercising, and may not be withdrawn without the written consent of the Seller as to whom it is given,
except that such exercise may be withdrawn unilaterally by the exercising party if there is any legal prohibition as to a party’s consummation of its purchase or sale hereunder. 

(i) Counterparts; Facsimiles. This Agreement may be executed in two or more counterparts, each of which shall be deemed an
original, but all of which together shall constitute one and the same instrument. A facsimile, telecopy or other reproduction of this Agreement may be executed by one or more parties hereto and delivered by such party by facsimile or any similar
electronic transmission device pursuant to which the signature of or on behalf of such party can be seen. Such execution and delivery shall be considered valid, binding and effective for all purposes. At the request of any party hereto, all parties
hereto agree to execute and deliver an original of this Agreement as well as any facsimile, telecopy or other reproduction hereof. 
 (j) Titles and Subtitles. The titles and subtitles used in this Agreement are used for convenience only and are not to be considered in construing or interpreting this Agreement. 

(k) Delays or Omissions. No delay or omission to exercise any right, power or remedy accruing to any party under this Agreement,
upon any breach or default of any other party under this Agreement, shall impair any such right, power or remedy of such non-breaching or non-defaulting party nor shall it be construed to be a waiver of any such breach or default, or an acquiescence
therein, or of or in any similar breach or default thereafter occurring; nor shall any waiver of any single breach or default be deemed a waiver of any other breach or default theretofore or thereafter occurring. Any waiver, permit, consent or
approval of any kind or character on the part of any party of any breach or default under this Agreement, or any waiver on the part of any party of any provisions or conditions of this Agreement, must be in writing and shall be effective only to the
extent specifically set forth in such writing. All remedies, either under this Agreement or by law otherwise affording to any party, shall be cumulative and not alternative. 
 (l) Entire Agreement. This Agreement constitutes the entire agreement of the parities with respect to the subject matter hereof and supersedes in their entirety all other agreements or
understandings between or among the parties hereto, both oral and written, with respect to such specific subject matter. 
 (m)
Amendment and Restatement. The Prior Agreement is hereby superseded and amended in its entirety and restated in this Agreement. All provisions of, rights granted and covenants made in the Prior Agreement are hereby terminated, waived,
released and superseded in their entirety and shall have no further force or effect. 
 (n) New Investors.
Notwithstanding anything herein to the contrary, if pursuant to an agreement (including the B-1 Extension Purchase Agreement, as may be amended time to time), additional parties may purchase Series B-1 Shares as “Purchasers”
thereunder, then each such Purchaser shall become a Party to this Agreement as an “Investor” hereunder, without the need 

  
 -11-

 
for any consent, approval or signature of any Investor when such Purchaser has both (i) purchased Series B-1 Shares under such agreement, and paid the Company all consideration payable for
such shares and (ii) executed a copy of this Agreement as an “Investor.” 
 [REMAINDER OF PAGE
INTENTIONALLY LEFT BLANK] 

  
 -12-

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

			
	COMPANY:
	
	 SAGENT HOLDING CO.,
 a Cayman Islands exempted company

		
	By:	 	 /s/ Jeffrey Yordon

	Name: Jeffrey Yordon
	Title: President and Chief Executive Officer

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

			
	KEY SHAREHOLDERS:
	
	JEFFREY YORDON
		
	By:	 	 /s/ Jeffrey Yordon

	(signature)
	
	LORIN DRAKE
		
	 By:
	 	 /s/ Lorin Drake

	(signature)
	
	ANTHONY GULCZYNSKI
		
	 By:
	 	 /s/ Anthony Gulczynski

	(signature)

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

			
	KEY SHAREHOLDERS:
	
	VIVO VENTURES FUND CAYMAN V, L.P.
	
	By: Vivo Ventures Cayman V (GP), L.P.
	
	By: Vivo Ventures Cayman V General Partner Limited, its general partner
		
	 By:
	 	 /s/ Frank Kung

	(signature)
	
	Name: Frank Kung
	Title: Director
	
	VIVO VENTURES V AFFILIATES FUND, L.P.
		
	 By:
	 	 /s/ Frank Kung

	(signature)
	
	Name: Frank Kung
	Title: Managing Member of Vivo Ventures V, LLC, its General Partner

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

			
	KEY SHAREHOLDERS:
	
	VIVO VENTURES FUND CAYMAN VI, L.P.
	
	By: Vivo Ventures Cayman VI (GP), L.P.
	
	By: Vivo Ventures Cayman VI General Partner Limited, its general partner
		
	 By:
	 	 /s/ Frank Kung

	(signature)
	
	Name: Frank Kung
	Title: Director
	
	VIVO VENTURES VI AFFILIATES FUND L.P.
	
	By: Vivo Ventures VI, LLC, its Managing Member
		
	 By:
	 	 /s/ Frank Kung

	(signature)
	
	Name: Frank Kung
	Title: General Partner

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

			
	INVESTORS:
	
	VIVO VENTURES FUND CAYMAN V, L.P.
	
	By: Vivo Ventures Cayman V (GP), L.P.
	
	By: Vivo Ventures Cayman V General Partner Limited, its general partner
		
	 By:
	 	 /s/ Frank Kung

	(signature)
	
	Name: Frank Kung
	Title: Director
	
	VIVO VENTURES V AFFILIATES FUND, L.P.
		
	 By:
	 	 /s/ Frank Kung

	(signature)
	
	Name: Frank Kung
	Title: Managing Member of Vivo Ventures V, LLC, its General Partner

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

			
	INVESTORS:
	
	PACIFIC SEQUOIA HOLDINGS LLC
		
	By:	 	 /s/ John V. Jonson

	Name: John V. Jonson
	Title: Manager

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

			
	INVESTORS:
	
	THE SKOLL FOUNDATION
		
	By:	 	 /s/ John V. Jonson

	Name: John V. Jonson
	Title: Manager

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

			
	INVESTORS:
	
	THE SKOLL FUND
		
	By:	 	 /s/ John V. Jonson

	Name: John V. Jonson
	Title: Manager

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	WEYERHAEUSER COMPANY MASTER RETIREMENT TRUST
	
	Managed by Morgan Stanley Investment Management, Inc.
	
	By: The Bank of New York Mellon, not individually but solely in its capacity as Directed Trustee on behalf of the Trust
	
	By: /s/ Bernadette T.
Rist                                         
   
	Name: Bernadette T. Rist
	Authorized Signatory

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	 SAILORSHELL & CO. FOR THE BENEFIT OF
 MORGAN STANLEY AIP GLOBAL
 DIVERSIFIED FUND LP

	
	 By: Morgan Stanley Alternative Investment
         Partners LP, its general partner

	By: Morgan Stanley AIP GP LP, its general partner
	 By: Morgan Stanley Alternative Investments Inc.,
         its general partner

	
	By:  /s/ James
Sperans                                        
          
	Name: James Sperans
	Title: Managing Director
	
	 SAILORPIER & CO. FOR THE BENEFIT OF
 AURORA CAYMAN LIMITED

	
	 By: Morgan Stanley Investment Management Inc.,
         its investment manager

	
	By:  /s/ James
Sperans                                        
          
	Name: James Sperans
	Title: Managing Director

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	 STORMBAY & CO. FOR THE BENEFIT OF
 VIJVERPOORT HUIZEN C.V.

	
	 By: Morgan Stanley Alternative Investment
         Partners LP, its general partner

	By: Morgan Stanley AIP GP LP, its general partner
	 By: Morgan Stanley Alternative Investments Inc.,
         its general partner

	
	By:  /s/ James
Sperans                                        
          
	Name: James Sperans
	Title: Managing Director
	
	 STORMLAUNCH & CO. FOR THE BENEFIT OF
 MORGAN STANLEY PRIVATE MARKETS
 FUND III LP

	
	 By: Morgan Stanley Alternative Investment
         Partners LP, its general partner

	By: Morgan Stanley AIP GP LP, its general partner
	 By: Morgan Stanley Alternative Investments Inc.,
         its general partner

	
	By:  /s/ James
Sperans                                        
          
	Name: James Sperans
	Title: Managing Director

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	 STORMSTAR & CO. FOR THE BENEFIT OF
 MORGAN STANLEY PRIVATE MARKETS
 FUND EMPLOYEE INVESTORS III LP

	
	 By: Morgan Stanley Alternative Investment
 Partners LP, its general partner

	By: Morgan Stanley AIP GP LP, its general partner
	 By: Morgan Stanley Alternative Investments Inc.,
 its general partner

	
	By:  /s/ James
Sperans                                        
          
	Name: James Sperans
	Title: Managing Director
	
	NUCLEAR ELECTRIC INSURANCE LIMITED
	
	 By: Morgan Stanley Investment Management Inc.,
 its investment manager

	
	By:  /s/ James
Sperans                                        
          
	Name: James Sperans
	Title: Managing Director

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	FACTORY MUTUAL INSURANCE COMPANY
	
	By:  /s/ Paul
LaFleche                                        
          
	Name: Paul LaFleche
	Title: Senior Vice President of Investments

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	CNF INVESTMENTS II, LLC
	
	By: /s/ Robert J.
Flanagan                                        
    
	Name: Robert J. Flanagan
	Title: Manager

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	VIVO VENTURES VI AFFILIATES FUND L.P.
	By: Vivo Ventures VI, LLC, its Managing Member
	
	By: /s/ Frank
Kung                                         
             
	(signature)
	
	Name: Frank Kung
	Title: General Partner
	
	VIVO VENTURES FUND CAYMAN VI, L.P.
	By: Vivo Venture Cayman VI (GP), L.P.
	 By: Vivo Ventures Cayman VI General Partner
         Limited, its general partner

	
	By: /s/ Frank
Kung                                         
             
	(signature)
	
	Name: Frank Kung
	Title: Director

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	KEY GATE INVESTMENTS LIMITED
	
	By: /s/ Andrew
Lo                                         
               
	(signature)
	
	Name: Andrew Lo
	Title: Authorized Representative

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	LINK BEST CAPITAL LIMITED
	
	By: /s/ Shing Chi
Yap                                         
         
	(signature)
	
	Name: Shing Chi Yap
	Title: Director

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	WESTFIELD CAPITAL MANAGEMENT
	
	 By: Westfield Partners, L.L.C., its General Partner
 By: Westfield Capital Management Company, L.P.,
 it’s Manager

By: WMS General Partner, LLC, its General Partner

	
	By: /s/ William A.
Muggia                                        
  
	 William A. Muggia, an Authorized Person

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
THIRD AMENDED AND RESTATED 

RIGHT OF FIRST REFUSAL AND
CO-SALE AGREEMENT 

 Exhibit A 

Existing Investors 

Vivo Ventures Fund Cayman VI, L.P. 
 575
High Street, Suite 201 
 Palo Alto, CA 94301 
 Attn: Chen Yu 
 Vivo Ventures Fund Cayman V, L.P. 

c/o Vivo Ventures V, LLC 
 575 High Street, Suite
201 
 Palo Alto, CA 94301 
 Attn: Chen
Yu 
 Vivo Ventures VI Affiliates Fund, L.P. 
 575 High Street, Suite 201 
 Palo Alto, CA 94301 

Attn: Chen Yu 
 Vivo Ventures V Affiliates
Fund, L.P. 
 c/o Vivo Ventures V, LLC 
 575 High Street, Suite 201 
 Palo Alto, CA 94301 

Attn: Chen Yu 
 Stormlaunch & Co.
for the Benefit of Morgan Stanley Private Markets Fund III LP 
 c/o Morgan Stanley Alternative Investments Inc. 

100 Front Street, Suite 400 
 West Conshohocken,
Pennsylvania 19428-2881 
 Attn: Matthew Allen, Executive Director 
 Stormstar & Co. for the Benefit of Morgan Stanley Private Markets Fund Employee Investors III LP 
 c/o Morgan Stanley Alternative Investments Inc. 
 100 Front Street, Suite 400 

West Conshohocken, Pennsylvania 19428-2881 

Attn: Matthew Allen, Executive Director 
 CNF
Investments II, LLC 
 7500 Old Georgetown Road 
 Bethesda, MD 20814 
 Attn: Robert Flanagan 

Weyerhaeuser Company Master Retirement Trust 
 c/o Bank of New York Mellon 
 Legal Department 

500 Grant Street 
 BNY Mellon Center 

AIM: 151-1935 
 Pittsburgh, Pennsylvania
15258-0001 
 Attn: Bernadette Rist 

 Sailorshell & Co. for the benefit of Morgan Stanley AIP Global Diversified Fund LP

 c/o Morgan Stanley Alternative Investments Inc. 
 100 Front Street, Suite 400 
 West Conshohocken, Pennsylvania 19428-2881 

Attn: Matthew Allen, Executive Director 

Dohmen Investment Group, LLC 
 215 North
Water Street 
 Milwaukee, WI 53202 

Attn: John Vaughan, Chief Financial Officer 

Pacific Sequoia Holdings LLC 

  c/o Capricorn Management, LLC 

  250 University Avenue, Suite 300 

  Palo Alto, CA 94301 

  Attn: John Johnson 
   c/o
Mellon Global Securities Services 
   135 Santilli Highway 
   026-0035 
   Everett, MA 02149 

  Attn: Nicole Strazzulla 

  c/o Seiler & Company 

  1100 Marshall Street 

  Redwood City, CA 94063 

  Attn: James G. B. DeMartini III, CPA 

Stormbay & Co. for the benefit of Vijverpoort Huizen C.V. 
 c/o Morgan Stanley Alternative Investments Inc. 
 100 Front Street, Suite 400 

West Conshohocken, Pennsylvania 19428-2881 

Attn: Matthew Allen, Executive Director 

Sailorpier & Co. for the benefit of Aurora Cayman Limited 
 c/o Morgan Stanley Alternative Investments Inc. 
 100 Front Street, Suite 400 

West Conshohocken, Pennsylvania 19428-2881 

Attn: Matthew Allen, Executive Director 
 The
Skoll Foundation 
   c/o Capricorn Management, LLC 
   250 University Avenue, Suite 300 
   Palo Alto, CA 94301 

  Attn: John Johnson 
   c/o
Mellon Global Securities Services 
   135 Santilli Highway 
   026-0035 
   Everett, MA 02149 

  Attn: Nicole Strazzulla 

  c/o Seiler & Company 

  1100 Marshall Street 

  Redwood City, CA 94063 

  Attn: James G. B. DeMartini III, CPA 

 The Skoll Fund 
   c/o Capricorn Management, LLC 
   250 University Avenue, Suite 300

   Palo Alto, CA 94301 

  Attn: John Johnson 
   c/o
Mellon Global Securities Services 
   135 Santilli Highway 
   026-0035 
   Everett, MA 02149 

  Attn: Nicole Strazzulla 

  c/o Seiler & Company 

  1100 Marshall Street 

  Redwood City, CA 94063 

  Attn: James G. B. DeMartini III, CPA 

Factory Mutual Insurance Company 
 225
Wyman Street 
 Waltham, MA 02454 

Attn: Paul LaFleche, Senior Vice President of Investments 
 Nuclear Electric Insurance Limited 
 1201 North Market Street, 11th Floor 

Wilmington, DE 19801 
 Attn: Robert MacGovern,
Vice President - Investments 
 CIBC WMC, Inc. 
 425 Lexington Ave. 
 New York, NY 10017 
 Attn: Kathryn Casparian 
 Key Gate Investments Limited 

China Renaissance Capital Investment 
 Suite 305,
St. George’s Building 
 2 Ice House Street 
 Central Hong Kong 
 Hong Kong SAR 
 Attn: Andrew Lo 

 Exhibit B 

Key Shareholders 

Jeffrey Yordon 
 812 Lakeland Drive

 Schaumburg, IL 60173 
 Lorin
Drake 
 4065 Walt Whitman Road 

St. Charles, IL 60175 
 Anthony J. Gulczynski

 1232 Eagle Crest Drive 
 Lemont,
IL 60439 
 Vivo Ventures Fund Cayman VI, L.P. 
 575 High Street, Suite 201 
 Palo Alto, CA 94301 

Attn: Chen Yu 
 Vivo Ventures VI Affiliates
Fund, L.P. 
 575 High Street, Suite 201 
 Palo Alto, CA 94301 
 Attn: Chen Yu 
 Vivo Ventures Fund Cayman V, L.P. 
 c/o Vivo Ventures V, LLC 

575 High Street, Suite 201 
 Palo Alto, CA 94301

 Attn: Chen Yu 
 Vivo Ventures V
Affiliates Fund, L.P. 
 c/o Vivo Ventures V, LLC 
 575 High Street, Suite 201 
 Palo Alto, CA 94301 

Attn: Chen Yu 

 Exhibit C 

New Investors 
 Link
Best Capital Limited 
 Room 2201, 22/F., Far East Consortium Building 
 121, Des Voeux Road, 
 Central, Hong Kong. 
 Attn: Yap Shing Chi 
 Westfield Capital Management 

One Financial Center, 24th Floor 

Boston, MA 02111-2621 
 Attn: Matthew Strobeck

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