Document:

EX-10.13

Exhibit 10.13

OSI PHARMACEUTICALS, INC.

AMENDED AND RESTATED

STOCK INCENTIVE PLAN

NON-QUALIFIED STOCK OPTION

     THIS NON-QUALIFIED STOCK OPTION (this “Option”), by and between OSI PHARMACEUTICALS, INC., a
Delaware corporation (the “Company”), to [EXECUTIVE OFFICER] (the “Optionee”), an employee of
Prosidion Limited (the “UK Subsidiary”), is entered into as of the date set forth beneath the
Optionee’s name below. The Option is granted subject to a condition that any liability of the UK
Subsidiary (as employer or former employer of the Optionee) to pay secondary national insurance
contributions (“Secondary NIC”) in respect of the exercise, assignment or release of the Option
shall be the liability of the Optionee and payable by the Optionee and that the Optionee shall be
required to enter into an election in the form envisaged in Paragraph 313(1) of Schedule 1 to the
Social Security Contributions and Benefits Act 1992 (“Election”) to that effect when required to do
so by the UK Subsidiary provided that the Committee may in its discretion at any time or times
release the Optionee from this liability or reduce his liability thereunder unless that Election
has been entered into between the UK Subsidiary and the Optionee and that Election (or the
legislation which provides for such an Election to be effective) does not allow for such an
Election to be subsequently varied. For the avoidance of doubt the terms of the Election shall
include a statement to the effect that the Optionee is liable to pay any Secondary NIC arising on
the exercise of the Option even if he is no longer an employee of the UK Subsidiary and/or no
longer resident in the United Kingdom at the date of exercise.

     The Compensation Committee of the Board of Directors of the Company (the “Committee”) approved
on [INSERT DATE OF GRANT] (the “Grant Date”) the grant to the Optionee of a non-qualified stock
option to purchase shares of the Company’s common stock, par value $.01 per share (the “Common
Stock”), as hereinafter set forth. The option granted herein is (i) pursuant to the OSI
Pharmaceuticals, Inc. Amended and Restated Stock Incentive Plan, as amended (the “Plan”), a copy of
which has been provided to Optionee as of the date hereof, and (ii) not intended to qualify as an
“incentive stock option” as defined in Section 422 of the Internal Revenue Code of 1986, as
amended.

W I T N E S S E T H:

     1. Grant. On the Grant Date, the Company granted to the Optionee an option (the
“Option”) to purchase on the terms and conditions set forth herein and in the Plan all or any part
of an aggregate of [INSERT NUMBER OF SHARES] shares of Common Stock (the “Option Shares”), at the
purchase price of $[INSERT GRANT PRICE] per share (the “Option Price”).

 

 

     2. Vesting. Subject to the terms and conditions of this Agreement and the Plan, the
Optionee shall have the cumulative right to exercise the Option over a three year period, with
one-third of the Option Shares becoming exercisable on each of the third, fourth and fifth
anniversaries of the Grant Date, with any fractional number of Option Shares that would otherwise
become exercisable as of any such anniversary rounded to a whole integer as determined in the
discretion of the Committee.

     3. Term. The Option shall terminate in all events at 5:00 p.m. (local New York, New
York time) on [INSERT DATE IMMEDIATELY PRIOR TO SEVENTH ANNIVERSARY OF THE GRANT DATE] (the
“Termination Date”), unless sooner terminated as provided in Subparagraphs (a) or (b) below.

          a. Termination of Employment or Service. The Option shall terminate and shall no
longer be exercisable ninety (90) days after the Optionee’s employment (or service as an officer or
consultant) with the Company and any parent or subsidiary of the Company terminates, unless such
termination of employment or service was caused by the Optionee’s death or Retirement (as defined
in the Plan). The death or Retirement of the Optionee shall not affect the remaining term of the
Option. Following a termination of employment or service (including due to death or Retirement),
the Optionee (or the Optionee’s heirs or personal representatives if Optionee is deceased) may,
during the remaining term of the Option, purchase any remaining Option Shares which could have been
purchased on the date Optionee’s employment or service was terminated, but may not purchase any
Option Shares which would otherwise have first become purchasable following such termination of
employment or service.

          b. Sale or Reorganization. As provided in Section 6(h) of the Plan, if the Company is
merged or consolidated with another corporation, or if the property or stock of the Company is
acquired by another corporation, or if there is a separation, reorganization or liquidation of the
Company, the Board of Directors of the Company may, in its discretion, give Optionee a written
notice that the Option will terminate thirty (30) days after the date of such written notice. In
any such case, the Option will become immediately exercisable in full, notwithstanding Paragraph 2
above.

     4. Method of Exercise and Payment.

          a. Method of Exercise. Subject to Paragraph 4(c) below, the Option shall be exercised
through the Company’s broker-assisted stock option program (the “Broker Program”), in accordance
with the terms and conditions of the Broker Program as may be in effect from time to time.

          b. Taxes. It shall be a condition to the performance of the Company’s obligation to
issue or transfer Option Shares upon the exercise of the Option that the Optionee remit an amount
on an indemnity basis sufficient to satisfy any federal, state and/or local tax withholding
requirements (including any interest or penalties due in respect of such sums) arising in
connection with the exercise of the Option or the issuance of Option Shares, other than stock
transfer taxes, in each case in accordance with any terms and conditions of the Broker Program as
may be in effect from time to time. If the Company for any reason does not require the Optionee to
make a payment sufficient to satisfy such withholding requirements, any tax

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withholding payments (including any interest or penalties due in respect of such sums) made by
the Company to any federal, state or local tax authority with respect to the exercise of the Option
shall constitute a personal obligation of the Optionee to the Company, payable upon demand or, at
the option of the Company, by deduction from future compensation payable to the Optionee.

          c. National Insurance Contributions. No stock shall be allotted or transferred to the
Optionee by the Company until the UK Subsidiary has received an amount in cash equal to the amount
of the Secondary NIC for which the Optionee is liable under the terms of the Election (the “NIC
Amount”). The Optionee shall by completing the Election grant to the UK Subsidiary (as employer or
former employer of the Optionee) the irrevocable authority, as agent of the Optionee and on his
behalf, to appoint an Independent Transfer Agent to act as agent of the Optionee and on his behalf
to sell or procure the sale of sufficient of the Option Shares acquired on the exercise, assignment
or release of the Option and remit the net sale proceeds to the UK Subsidiary so that the net
proceeds payable to the UK Subsidiary are so far as possible equal to but not less than the NIC
Amount and the UK Subsidiary shall account to the Optionee for any balance. In this paragraph
4(c), “Independent Transfer Agent” means any person (other than the Company or any company
affiliated with the Company or any individual affiliated with any such company) who is registered
as a broker-dealer with the U.S. Securities and Exchange Commission and who is thereby able to sell
and transfer shares in the Company on behalf of the Optionee.

          d. Partial Exercise. To the extent otherwise exercisable, the Option may be exercised
in whole or in part, except that the Option may in no event be exercised with respect to fractional
shares.

     5. Transfers. The Option is not transferable by the Optionee otherwise than by will
or pursuant to the laws of descent and distribution in the event of the Optionee’s death, in which
event the Option may be exercised by the heirs or legal representatives of the Optionee. The
Option may be exercised during the lifetime of the Optionee only by the Optionee. Any attempt at
assignment, transfer, pledge or disposition of the Option contrary to the provisions hereof or the
levy of any execution, attachment or similar process upon the Option shall be null and void and
without effect. Any exercise of the Option by a person other than the Optionee shall be
accompanied by appropriate proofs of the right of such person to exercise the Option.

     6. Adjustments on Changes in Common Stock. In the event that dividends payable in
Common Stock during any fiscal year of the Company exceed in the aggregate five percent (5%) of the
Common Stock issued and outstanding at the beginning of the year, or in the event there is during
any fiscal year of the Company one or more splits, subdivisions or combinations of shares of Common
Stock resulting in an increase or decrease by more than five percent (5%) of the shares of Common
Stock outstanding at the beginning of the year, the number of Option Shares deliverable upon the
exercise thereafter of the Option shall be increased or decreased proportionately, as the case may
be, without change in the aggregate purchase price payable upon exercise of the Option. Common
Stock dividends, splits, subdivisions or combinations during any fiscal year which do not exceed in
the aggregate five percent (5%) of the Common Stock issued and outstanding at the beginning of such
year shall not result in any adjustment under the Option. All adjustments shall be made as of the
day such action necessitating such adjustment becomes effective.

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     7. Legal Requirements.

          a. Listing Requirements. If at any time the Board of Directors of the Company shall
determine, in its discretion, that the listing, registration, or qualification of any of the Option
Shares upon any securities exchange or under any state or federal law, or the consent or approval
of any governmental regulatory body, is necessary or desirable as a condition of, or in connection
with, the granting of the Option or the issue, transfer or purchase of Option Shares hereunder, the
Option may not be exercised in whole or in part unless such listing, registration, qualification,
consent, or approval shall have been effected or obtained free of any conditions not acceptable to
the Board of Directors of the Company.

          b. Securities Laws. The Company shall not be obligated to sell or issue any Option
Shares in any manner in contravention of the Securities Act of 1933, as amended, or any state or
foreign securities law. The Board of Directors of the Company or the Committee may, at any time,
require, as a condition to the exercise of the Option, the representation or agreement of the
Optionee to the effect that the Option Shares issuable upon exercise of the Option are acquired by
the Optionee for investment purposes and not with a view to the resale or distribution thereof, and
may require such other representations and documents as may be required to comply with applicable
securities laws.

     8. Administration. The Option has been granted pursuant to, and is subject to the
terms and provisions of, the Plan. All terms used herein which are defined in the Plan and not
otherwise defined herein shall have the same meanings as in the Plan. To the extent that the
provisions hereof conflict with those of the Plan, the provisions of the Plan shall control. All
decisions or interpretations made by the Committee (as designated under the Plan) regarding any
issue or question arising under the Option or the Plan shall be final, binding and conclusive on
the Company and the Optionee.

     9. Rights as Stockholder. The Optionee shall have none of the rights of a stockholder
with respect to the Option Shares unless and until such Option Shares shall be issued to the
Optionee upon the exercise of the Option. Except as provided in Paragraph 6 above, no adjustments
shall be made for dividends or other rights for which the record date is prior to the date the
stock certificate is issued.

     10. Continued Employment or Service. Nothing contained herein or in the Plan shall
confer any right to continue in the employ or service of the UK Subsidiary, the Company or any
parent or other subsidiary of the Company or interfere in any way with the right of the UK
Subsidiary, the Company or any parent or other subsidiary of the Company to terminate the
employment, services, responsibilities or duties of the Optionee at any time for any reason
whatsoever.

     11. Sale of Option Shares. Unless otherwise provided by the Committee, no Option
Shares acquired upon exercise of the Option may be sold or otherwise disposed of by the Optionee
within six months from the Grant Date.

     12. Notices. Any notice to be given to the Company hereunder shall be delivered
personally to the Secretary of the Company or mailed or delivered to the Company at its

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principal executive office, addressed to the attention of the Secretary, and any notice to be
given to the Optionee hereunder shall be delivered personally or mailed or delivered to the
Optionee at the address then appearing on the records of the Company. Such addresses may be
changed at any time by notice from one party to the other. Notices given hereunder shall be in
writing, and shall be deemed to have been duly given upon delivery thereof, if personally
delivered, or three days after being deposited in the United States mail, registered or certified
mail, properly addressed, with proper postage and fees prepaid, or one day after being deposited
with a delivery service guaranteeing overnight delivery, properly addressed, with fees paid by the
sender.

     13. Governing Law. This Option, the documents to be entered into pursuant thereto,
and all matters arising from or connected with it are governed by and shall be construed in
accordance with the laws of England and Wales.

     14. Binding Effect. This Option shall be binding upon and inure to the benefit of the
parties hereto, including the successors and assigns of the Company and the heirs and personal
representatives of the Optionee.

     15. Counterparts. This Option may be executed simultaneously in two or more
counterparts, each of which shall be deemed an original, but all of which together shall constitute
one and the same instrument.

     IN WITNESS WHEREOF, the parties have entered into this Non-Qualified Stock Option as of the date
set forth below.

	 	 	 
	 

	 	OSI PHARMACEUTICALS, INC.
	 
	 	 
	 
	 	 
	 

	 	 
	 

	 	Name:
	 

	 	Title:
	 
	 	 
	 

	 	ACCEPTED BY (OPTIONEE):
	 
	 	 
	 
	 	 
	 

	 	 
	 

	 	Name: [EMPLOYEE NAME]
	 
	 	 
	 
	 	 
	 

	 	 
	 

	 	Date:

-5-EX-10.20

Exhibit 10.20

OSI PHARMACEUTICALS, INC.

AMENDED AND RESTATED STOCK INCENTIVE PLAN

RESTRICTED STOCK UNIT AGREEMENT

     THIS RESTRICTED STOCK UNIT AGREEMENT (the “Agreement”), by and between OSI PHARMACEUTICALS,
INC., a Delaware corporation (the “Company”), and [EXECUTIVE OFFICER] (the “Employee”), is entered
into as of the date set forth beneath the Employee’s name below. Capitalized terms, unless
otherwise defined herein, shall have their respective meanings as set forth in the OSI
Pharmaceuticals, Inc. Amended and Restated Stock Incentive Plan, as amended (the “Plan”).

     WHEREAS, the Compensation Committee of the Board of Directors of the Company (the “Committee”)
approved on [INSERT DATE OF GRANT] (the “Grant Date”) the grant of Restricted Stock Units (as
defined below) to the Employee, as described herein; and

     WHEREAS, the grant of Restricted Stock Units is subject to a condition that any liability of
the Company and its affiliates to pay secondary national insurance contributions in respect of the
Restricted Stock Units shall be the liability of the Employee and that the Employee shall be
required to enter into an election pursuant to Paragraph 3B(1) of Schedule 1 of the Social Security
Contributions and Benefits Act 1992;

     NOW, THEREFORE, the parties hereto mutually agree to the following terms and conditions of
this Agreement:

          1. Grant of Restricted Stock Units. The Company hereby grants to the Employee [INSERT NUMBER
OF RESTRICTED STOCK UNITS] Restricted Stock Units. For the purposes of this Agreement, a
“Restricted Stock Unit” shall mean the contractual right to receive one share of Common Stock of
the Company, par value $.01 per share (the “Common Stock”), subject to the terms and conditions of
this Agreement and the Plan.

          2. Vesting and Forfeiture. Subject to the terms and conditions of this Agreement and the
Plan, Restricted Stock Units granted under this Agreement shall vest over a period of four (4)
years, with one quarter (25%) of the Restricted Stock Units vesting on each of the next four
anniversaries of the Grant Date, with any fractional number of Restricted Stock Units that would
otherwise become vested as of any such anniversary rounded to a whole integer as determined in the
discretion of the Committee. On the date that the Employee’s employment (or service as an officer,
consultant or member of the Board of Directors of the Company) with the Company and any parent or
subsidiary of the Company terminates, including, without limitation, due to death or Retirement,
all unvested Restricted Stock Units granted hereunder shall be forfeited, and the Employee shall
have no further rights with respect to such forfeited Restricted Stock Units.

          3. Settlement of Restricted Stock Units. Settlement for any vested Restricted Stock Units
shall be in shares of Common Stock (collectively, the “Settlement

 

 

Shares”). For the purposes of this Agreement, the “Settlement Date” shall mean the date upon
which one or more Restricted Stock Units vest pursuant to this Agreement. The Company shall
deliver the Settlement Shares to the Employee as soon as reasonably practicable following the
applicable Settlement Date. Such Settlement Shares will be issued and evidenced in such manner as
the Committee in its discretion shall deem appropriate, including, without limitation, book-entry,
registration or issuance of one or more stock certificates. Upon issuance of the Settlement
Shares, the number of Restricted Stock Units equal to the Settlement Shares shall be extinguished
and such number of Restricted Stock Units will no longer be considered to be held by the Employee
for any purpose.

          4. Restriction on Transferability. Restricted Stock Units granted hereunder shall not be
sold, assigned, transferred, exchanged, pledged or otherwise encumbered or disposed of in any
manner by the Employee, except as otherwise approved by the Committee.

          5. Securities Laws. The Company shall not be obligated to issue or deliver any shares of
Common Stock under this Agreement in any manner in contravention of the Securities Act of 1933, as
amended, any other federal or state securities law or the rules of any exchange or market system
upon which the Common Stock is traded. The Board of Directors of the Company or the Committee may,
at any time, require, as a condition to the issuance or delivery of shares of Common Stock
hereunder, the representation or agreement of the Employee to the effect that the shares issuable
hereunder are acquired by the Employee for investment purposes and not with a view to the resale or
distribution thereof, and may require such other representations and documents as may be required
to comply with applicable securities laws or the rules of any applicable exchange or market system.

          6. Withholding of Applicable Taxes. It shall be a condition to the Company’s obligation to
deliver the Settlement Shares to the Employee and the Company or its affiliates shall be entitled
to deduct from the Settlement Shares under the Plan any taxes, social security contributions, or
any other amounts required by any government to be withheld from any such Settlement Shares,
including applicable federal, state or local withholding taxes (such amount, the “Withholding
Amount”). The Employee agrees that the Company, or any affiliate, as the case may be, will have
the right to withhold from the Settlement Shares a sufficient number of shares of Common Stock to
be sold in order to satisfy in full the Withholding Amount on behalf of the Employee. The Employee
shall be solely and personally responsible for the payment of any applicable taxes (including
interest and penalties thereon) due on the Settlement Shares hereunder (including the removal of
any restrictions or variation of any rights relating to the Settlement Shares), and the Employee
agrees to indemnify the Company and its affiliates against payment of such amounts.

          7. Subject to Terms of Plan. The Restricted Stock Units are subject to the terms and
provisions of the Plan. To the extent that the provisions hereof conflict with those of the Plan,
the provisions of the Plan shall control. All decisions or interpretations made by the Committee
regarding any issue or question arising under this Agreement or the Plan shall be final, binding
and conclusive on the Company and the Employee.

          8. No Rights as Stockholder. The Restricted Stock Units granted under this Agreement do not
provide the Employee with any of the rights of a stockholder of the Company, including, without
limitation, the right to vote or receive any dividends declared or paid on the

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Common Stock, unless and until shares of Common Stock relating to the Restricted Stock Units have
been issued to the Employee.

          9. Continued Employment or Service. Nothing contained herein or in the Plan shall confer any
right to continue in the employ or service of the Company or any parent or subsidiary of the
Company or interfere in any way with the right of the Company or any parent or subsidiary of the
Company to terminate the employment, services, responsibilities or duties of the Employee at any
time for any reason whatsoever.

          10. Binding Effect. This Agreement shall be binding upon and inure to the benefit of the
parties hereto, including the successors and assigns of the Company.

          11. Governing Law. This Agreement will be interpreted and enforced under the laws of the
State of New York, other than any conflicts or choice of law rule or principle that might otherwise
refer construction or interpretation of this Agreement to the substantive law of another
jurisdiction. The parties will submit any dispute or claim arising under this Agreement to the
exclusive jurisdiction of the U.S. federal or New York state courts within the New York counties of
New York, Nassau, or Suffolk, and the parties hereby submit to, and waive any objection to,
personal jurisdiction and venue in such courts for such purpose.

          12. Counterparts. This Agreement may be executed simultaneously in two or more counterparts,
each of which shall be deemed an original, but all of which together shall constitute one and the
same instrument.

     IN WITNESS WHEREOF, the parties have entered into this Restricted Stock Unit Agreement as of
the date set forth below.

	 	 	 	 	 
	 	OSI PHARMACEUTICALS, INC.	 
	 
	 	 	 
	 	Name:	 
	 	Title:	 
	 	 	 
	 
	 	EMPLOYEE	 
	 
	 	 	 
	 	[EMPLOYEE]	 
	 	 	 
	 	Date:	 

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