Document:

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                                                                    EXHIBIT 10.5
                             [Note: Asterisks denote material that has been
                             separately filed with the SEC pursuant to a request
                             for confidential treatment.]

                                          Harbour Pointe Tech Center, Washington
                                                                (LONG FORM 2000)

                             BASIC LEASE INFORMATION

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<S>                               <C>
LEASE EXECUTION DATE:             October 19, 2000

TENANT:                           COMBIMATRIX CORPORATION

ADDRESS OF TENANT:                6500 Harbour Heights Parkway, Suite 301, Mukilteo,
                                  Washington 98275

CONTACT:                          Patrick de Maynadier  Telephone: (425) 396-5940 (ext. 219)

LANDLORD:                         WIREDZONE PROPERTY, L.P.

ADDRESS OF LANDLORD:              6060 N. Central Expressway, Suite 642
                                  Dallas, Texas 75206

CONTACT:                          Scott Anderson             Telephone:  (425) 315-1354

PREMISES:                         Suites No.201 and 301 and the hazardous materials storage
                                  area in the office building (the "BUILDING") located on the
                                  land described as 6500 Harbour Heights Parkway, Mukilteo,
                                  Washington and known as Harbour Pointe Tech Center, as more
                                  particularly described on Exhibit "A" (the "LAND").  The
                                  Premises shall also include that certain hazardous materials
                                  storage area on the ground floor level of the Building.  The
                                  Premises are outlined on the plan attached to the Lease as
                                  Exhibit "B" and are deemed to contain 85,414 square feet of
                                  Rentable Space based on a useable square footage of 74,273
                                  and a load factor of 15%.  Tenant hereby acknowledges that
                                  Tenant's architect has certified to the Rentable Space in
                                  the Premises.

LEASE TERM:                       Ninety-six (96)  months, commencing November 1, 2000 (the
                                  "COMMENCEMENT DATE") and ending at 5:00 p.m., October 31,
                                  2008, subject to extension and earlier termination as
                                  provided in the Lease.  Following Lease execution, Landlord
                                  shall provide Tenant with immediate access to the Premises
                                  at no charge.

BASE RENTAL:                      $    *     per month, which is based on an annual Base
                                  Rental of $   *   per rentable square foot per year, which
                                  Tenant agrees to pay to Landlord at P.O. Box 972170 Dept.
                                  Code 7002, Dallas, Texas 75397-2170 (or at such other place
                                  as Landlord from time to time may designate in writing) in
                                  advance and without demand on the first day of each calendar
                                  month during and throughout the Lease Term.  Payments may
                                  also be wired to Landlord as follows: Bank One - Texas; ABA
                                  #111000614; WiredZone Property, L.P. Lockbox; Acct. No.
                                  1588316057.

                                  *see Schedule 106 attached hereto and incorporated herein
                                  for all purposes

PREPAID RENTAL:                   $64,837.85, representing payment of Base Rental for the
                                  first month of the Lease Term, to be paid on the date of
                                  execution of this Lease.

SECURITY DEPOSIT:                 The Security Deposit hereunder shall be in the amount which
                                  represents all of Landlord's transaction costs associated
                                  with this Lease plus the value of the tenant improvement
                                  Allowance described in the Leasehold Improvements Agreement
                                  attached hereto as Exhibit "D".  Such Security Deposit
                                  shall be held by Landlord pursuant to the provisions of
                                  Paragraph 29 of the Lease. As an alternative to a cash
                                  security deposit, Tenant may deposit with Landlord a clean,
                                  irrevocable letter of credit from an institution acceptable
                                  to Landlord.  At the time of Lease execution, Tenant shall
                                  deliver to Landlord the sum of $640,000 (either in cash or
                                  in the form of a letter of credit as set forth above) with
                                  such amount to thereafter be increased (either by
                                  supplemental cash deposit or amendment to the previously
                                  delivered letter of credit) as the tenant improvement
                                  allowance is advanced by Landlord pursuant to the terms of
                                  the Leasehold Improvements Agreement. At the time Landlord
                                  has fully advanced such tenant improvement allowance the
                                  Security Deposit shall be in the aggregate amount of
                                  $1,500,000.  Such security deposit, however,  shall be
                                  reduced to $301,084.35 (i.e., the equivalent of two  months
                                  of full Base Rental) once Tenant achieves and provided it
                                  thereafter maintains a net cash reserve in excess of
                                  $100,000,000 or has successfully completed an Initial
                                  Public Offering resulting in and thereafter maintaining a
                                  capitalization value in excess of $100,000,000.  After
                                  execution of the Lease, the parties shall have the option
                                  of negotiating a mutually satisfactory substitution of all
                                  or a portion of such Security Deposit, for a warrant for
                                  common equity in the Tenant

SOLE PERMITTED USE:               General office, research, development, production and sale
                                  of  biological
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                                  array processors with related instrumentation,
                                  software, bio-informatics and related
                                  chemicals and other materials, products and
                                  services related to the foregoing used
                                  primarily in the bio-tech/bio-pharmaceutical,
                                  life science, material science, energy,
                                  agricultural and defense industries (subject
                                  to applicable zoning ordinances and building
                                  codes). In addition, Tenant may request to
                                  broaden the definition of Sole Permitted Use
                                  with Landlord's prior written consent, such
                                  consent not to be unreasonably withheld or
                                  delayed. Tenant shall be responsible for
                                  verifying that its proposed use complies with
                                  applicable zoning laws and building codes and
                                  by its execution hereof certifies that it has
                                  received satisfactory evidence of such
                                  compliance. To the best of Landlord's
                                  knowledge, there are no restrictions for
                                  Tenant's intended use or any eminent domain or
                                  condemnation proceedings pending that could
                                  adversely affect Tenant's intended use of the
                                  Premises.

TENANT'S                          25.52%, which is the percentage obtained by dividing
PROPORTIONATE SHARE:              (i) the 85,414 rentable square feet in the Premises by
                                  (ii) the 334,758 rentable square feet in the
                                  Building; provided, however, Tenant's
                                  Proportionate Share shall be calculated
                                  utilizing the Rentable Space in the Premises
                                  from time to time per the schedule and terms
                                  of Rider No. 106 to this Lease (i.e., in
                                  months 1-10 the rentable square footage will
                                  be 42,868 and therefore Tenant's Proportionate
                                  Share would equal 12.81%).
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The foregoing Basic Lease Information is incorporated into and made a part of
the Lease identified above. If any conflict exists between any Basic Lease
Information and the Lease, then the Lease shall control.

LANDLORD:                                     TENANT:
--------                                      ------

WIREDZONE PROPERTY, L.P.                      COMBIMATRIX CORPORATION

By:     WiredZone Property GenPar, LLC,
        its general partner                   By:
                                                 -------------------------------
                                              Its:
                                                   -----------------------------
        By:
           -------------------------
        Its:
             -----------------------

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                                TABLE OF CONTENTS

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PARAGRAPH                                                                                 PAGE NO.
---------                                                                                 --------
<S>                                                                                       <C>
1.      Definitions and Basic Provisions.....................................................1
2.      Lease of Premises....................................................................1
3.      Services by Landlord.................................................................2
4.      Additional Rental....................................................................3
5.      Electricity..........................................................................3
6.      Payments and Performance.............................................................4
7.      Tenant Plans and Specifications - Installation of Improvements.......................4
8.      Completion of Improvements and Commencement of Rent..................................4
9.      Relocation of Premises...............................................................4
10.     Repairs and Reentry..................................................................4
11.     Assignment and Subletting............................................................4
12.     Alterations and Additions by Tenant..................................................5
13.     Legal Use; Violations of Insurance Coverage; Nuisance................................5
14.     Laws and Regulations.................................................................5
15.     Indemnity, Liability and Loss or Damage..............................................5
16.     Rules of the Building................................................................6
17.     Entry for Repairs and Inspection.....................................................6
18.     Condemnation.........................................................................6
19.     Landlord's Lien and Security Interest................................................6
20.     Abandoned Property...................................................................7
21.     Holding Over.........................................................................7
22.     Fire and Casualty....................................................................7
23.     Entire Agreement and Amendment; No Representations or Warranties; No Memorandum
        of Lease.............................................................................7
24.     Transfer of Landlord's Rights........................................................8
25.     Default..............................................................................8
26.     Waiver; Attorney's Fees..............................................................9
27.     Quiet Possession....................................................................10
28.     Severability........................................................................10
29.     Security Deposit....................................................................10
30.     No Subrogation; Insurance...........................................................10
31.     Binding Effect......................................................................11
32.     Notices.............................................................................11
33.     Brokerage...........................................................................11
34.     Subordination.......................................................................11
35.     Joint and Several Liability.........................................................11
36.     Building Name and Address...........................................................12
38.     Mechanic's Liens....................................................................12
39.     Taxes and Tenant's Property.........................................................12
40.     Constructive Eviction...............................................................12
41.     Landlord's Liability................................................................13
42.     Execution by Landlord...............................................................13
43.     No Waiver...........................................................................13
44.     No Third Party Beneficiary..........................................................13
45.     Number and Gender...................................................................13
46.     Force Majeure.......................................................................13
47.     Hazardous and Toxic Materials.......................................................13
48.     Telecommunications..................................................................14
49.     Landlord's Fees.....................................................................14
50.     No Light, Air or View Easement......................................................14
51.     APPLICABLE LAW; CONSENT TO JURISDICTION.............................................15
52.     WAIVER OF JURY TRIAL................................................................15
53.     Confidentiality.....................................................................15
54.     Back-Up Generator...................................................................15
55.     Signage.............................................................................15
56.     Special Tenant Installations........................................................15
57.     Category 5 Cabling..................................................................15
58.     Miscellaneous.......................................................................15
</TABLE>

Exhibit "A"    Legal Description
Exhibit "B"    Floor Plan of Premises
Exhibit "C"    Holidays
Exhibit "D"    Leasehold Improvements Agreement
Exhibit "E"    Acceptance of Premises Memorandum
Exhibit "F"    Building Rules and Regulations
Rider No. 101  Parking Facilities
Rider No. 102  Tenant's Option to Renew
Rider No. 103  Expansion Option
Rider No. 104  Right of First Refusal
Rider No. 106  Schedule of Base Rental

                                 LEASE AGREEMENT

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<PAGE>   4

       THIS LEASE AGREEMENT (the "LEASE") is made and entered into as of the
_____ day of October, 2000, by and between WIREDZONE PROPERTY, L.P. ("LANDLORD")
and COMBIMATRIX CORPORATION, a Delaware corporation ("TENANT").

       1. DEFINITIONS AND BASIC PROVISIONS. The definitions and basic provisions
set forth in the Basic Lease Information (the "BASIC LEASE INFORMATION")
executed by Landlord and Tenant contemporaneously herewith are incorporated
herein by reference for all purposes. The additional terms defined below shall
have the respective meanings stated when used elsewhere in this Lease, and such
terms and the following basic provisions constitute an integral part of this
Lease:

              (a) "NORMAL BUSINESS HOURS": From 7:00 a.m. until 6:00 p.m. on
       weekdays (except Holidays, as defined on Exhibit "C" attached hereto and
       made a part hereof for all purposes) and 7:00 a.m. until 12:00 p.m. on
       Saturdays (except Holidays). Tenant shall have access to the Building and
       its Common Facilities (including, without limitation, the freight
       elevators, shipping and receiving docks, cafeteria and fitness room) on a
       24 hours per day, 7 days a week basis; subject, however, to reasonable
       limitations resulting from Landlord's access control systems implemented
       for security purposes. Note that Tenant shall also have access to the
       Building's conference room facilities on a reservation and cost basis on
       the same terms available to other tenants as established by Landlord in
       Landlord's reasonable discretion.

              (b) "RENTABLE SPACE": (per BOMA 1996 standards) (i) in the case of
       a single tenancy floor, all floor area measured at the floor from the
       inside surface of the outer glass line of the Building to the inside
       surface of the opposite outer glass line excluding only the areas (the
       "SERVICE AREAS") used for Building stairs, fire towers, elevator shafts,
       flues, vents, stacks, major pipe shafts and vertical ducts (which Service
       Areas shall be measured from the outside face of walls enclosing such
       Service Areas), but including any such Service Areas which are for the
       specific use of the particular tenant such as special stairs or
       elevators, plus an allocation of the square footage of the Building's
       elevator machine rooms, mechanical and electrical rooms, and public
       lobbies, and (ii) in the case of a floor to be occupied by more than one
       tenant, all floor areas within the inside surface of the outer glass
       walls enclosing the Premises and measured to either (A) the mid-point of
       the walls separating areas leased by or held for lease to other tenants
       and/or (B) to the tenant's side of walls adjacent to corridors, elevator
       foyers, restrooms, mechanical rooms, janitor closets, vending areas and
       other similar facilities for the use of all tenants on the particular
       floor (hereinafter sometimes called the "COMMON AREAS"), but including a
       proportionate part of the Common Areas located on such floor based upon
       the ratio which the tenant's rentable space (excluding Common Areas) on
       such floor bears to the aggregate rentable space (excluding Common Areas)
       on such floor, or other reasonable basis mutually agreed to by Landlord
       and Tenant, plus an allocation of the square footage of the Building's
       elevator machine rooms, mechanical and electrical rooms, and public
       lobbies. No deductions from Rentable Space shall be made for columns or
       projections necessary to the Building. The Rentable Space in the Premises
       has been calculated on the basis of the foregoing definition and is
       hereby stipulated for all purposes hereof to be as stated in the Basic
       Lease Information, whether the same should be more or less as a result of
       minor variations resulting from actual construction and completion of the
       Premises for occupancy so long as such work is done in substantial
       accordance with the terms and provisions hereof. Notwithstanding anything
       to the contrary contained herein, the standard of measurement utilizes a
       load factor of 15%.

              (c) "RIDER": Collectively, Rider No(s). 101, 102, 103, 104 and
       106, which are attached hereto, contain additional provisions of this
       Lease, and are hereby incorporated in, and made a part of, this Lease.
<PAGE>   5
              (d) "EXHIBITS": The following Exhibits are attached to and made a
       part of this Lease for all purposes:

                      A - Land
                      B - Floor Plan of Premises
                      C - Holidays
                      D - Leasehold Improvements Agreement
                      E - Acceptance of Premises Memorandum
                      F - Building Rules and Regulations

       2. LEASE OF PREMISES. In consideration of the obligation of Tenant to pay
rent as herein provided and in consideration of the other terms, covenants, and
conditions hereof, Landlord hereby demises and leases to Tenant, and Tenant
hereby leases and takes from Landlord, the Premises, together with the right to
use in common with others the Common Areas, for the Lease Term specified herein,
all upon and subject to the terms and conditions set forth herein. This Lease
and the obligations of Landlord hereunder are conditioned upon faithful
performance by Tenant of all of the agreements and covenants herein set out and
agreed to by Tenant. Tenant agrees and acknowledges that there is excluded from
Tenant's use of the Premises (whether the Premises are or include one or more
full floors within the Building) and Landlord hereby expressly reserves for its
sole and exclusive use, any and all mechanical, electrical, telephone and
similar rooms, janitor closets, elevator, pipe and other vertical shafts and
ducts, flues, stairwells, any area above the acoustical ceiling, and any other
areas not specifically shown on Exhibit "B" as being part of the Premises.
Landlord acknowledges that Paragraph 56 of this Lease identifies certain special
installations by Tenant that shall require access to some of the aforementioned
Service Areas and to the extent such special installations are approved as part
of Tenant's Approved Working

                                       4
<PAGE>   6

Drawings and Section 56 of this Lease, Tenant shall also have access to such
areas on a non-exclusive basis and in coordination with Landlord's on-site
property manager.

       3. SERVICES BY LANDLORD. Landlord agrees to furnish the following
services to the Premises, as long as Tenant is not in default of a material
obligation under this Lease, all of such services to be at Landlord's cost and
expense except as specifically provided to the contrary elsewhere in this Lease:

              (a) Cold water (at the normal temperature of the supply of water
       to the Building) for Tenant's laboratory use and lavatory, water fountain
       and toilet purposes, and hot water (from the regular Building supply at
       prevailing temperatures) for lavatory purposes, all of such water service
       to be supplied from the regular supply of water to the Building at points
       of supply provided for general use of tenants of the Building through
       fixtures installed by Landlord or by Tenant with Landlord's consent which
       consent shall not be unreasonably withheld, conditioned or delayed;
       provided, however, nothing contained herein shall require Landlord to
       furnish hot water to any kitchen, bar or other such lavatory facility in
       the Premises. Tenant acknowledges that to the extent Tenant's laboratory
       use results in an excessive level of water being used by Tenant as
       compared to other tenants in the Building, that Landlord may require the
       Premises' water consumption to be separately metered, at Tenant's cost,
       and for Tenant to thereafter reimburse Landlord directly for Tenant's
       water usage in the Premises.

              (b) Heated and refrigerated air conditioning in season during
       Normal Business Hours, and at such temperature and in such amounts as are
       reasonably considered by Landlord to be standard. Such services at all
       other times shall be furnished only at the request of Tenant, who shall
       bear the entire cost thereof. Whenever machines or equipment that
       generate abnormal heat and affect the temperature otherwise maintained by
       the air conditioning system are used in the Premises, Landlord shall have
       the right to install supplemental air conditioning units in the Premises,
       and the cost thereof, including the cost of installation, operation, use
       and maintenance, shall be paid by Tenant to Landlord from time to time
       promptly on demand. The hourly charge for heating, ventilation and air
       conditioning ("HVAC") overtime usage shall be an amount equal to the
       actual cost associated with providing such overtime HVAC plus an
       administrative charge of 15%. Notwithstanding the foregoing, Tenant shall
       not be charged for HVAC overtime usage while and to the extent either the
       existing 80-ton chiller is (1) operating during Normal Business Hours or
       (2) dedicated solely for Tenant's use. Tenant shall have a four (4) month
       option period following the Commencement Date in which to request that
       Landlord dedicate for Tenant's sole use the existing 80-ton chiller in
       connection with Tenant's activities on the second floor of the Building
       and upon demonstrating reasonable basis for such need, Landlord shall use
       its best efforts to so dedicate the chiller; provided, however, Tenant
       shall be solely responsible for the costs associated with using,
       maintaining and repairing same. Tenant shall reimburse Landlord on a
       monthly basis for all such costs associated therewith and Tenant
       acknowledges that Landlord will perform such maintenance and repair
       obligations. Tenant acknowledges that the costs associated with using,
       maintaining and repairing any of the HVAC systems related to all of
       Tenant's "clean room" facilities shall be Tenant's sole cost and
       responsibility.

              (c) Operatorless passenger elevator service in common with other
       tenants for ingress and egress from the Premises, provided that Landlord
       may reasonably limit the number of elevators to be in operation at times
       other than Normal Business Hours, and service elevator(s) in common with
       other tenants but only when scheduled through the management of the
       Building.

              (d) Such janitorial cleaning services as may, in the reasonable
       judgment of Landlord, be standard for office use.

              (e) Electric current in the manner and to the extent deemed by
       Landlord to be standard for the Building, but in no event less than 7
       watts per square foot (i.e., 5 watts for power and 2 watts for Building
       standard lighting).

              (f) Security services which shall consist of two security
       personnel during Normal Business Hours and one security person at all
       other times, with such personnel to be primarily stationed in the main
       entrance of the Building's lobby.

              (g) Food services in the Building's common cafeteria at such time
       as either (1) the Building is 75% occupied or (2) Tenant and other
       tenants at the Building have, in the aggregate, over 500 employees
       located at the Building. Prior to such time, Landlord will use its good
       faith efforts to provide or facilitate lunch catering services to Tenant.

       Except as provided hereinbelow, failure to any extent to furnish or any
stoppage of these defined utilities and services resulting from any cause
whatsoever shall not render Landlord liable in any respect for damages to either
person, property or business, nor be construed as an eviction of Tenant, nor
entitle Tenant to any abatement of rent, nor relieve Tenant from fulfillment of
any covenant or agreement contained herein. Except as provided hereinbelow,
should any malfunction of the Building improvements or facilities (which by
definition do not include any improvements or facilities of Tenant) occur for
any reason, Landlord shall use reasonable diligence to repair same promptly, but
Tenant shall have no claim for rebate or abatement of rent or damages on account
of such malfunction or of any interruptions in service occasioned thereby or
resulting therefrom. Notwithstanding the foregoing, in the event such stoppage
or interruption of utilities or services exists for more than seven (7)
consecutive days and is the result of a cause other than (i) a fire or casualty
which shall be controlled by Section 22 of this Lease, (ii) the actions of
Tenant or its agents, servants, contractors, employees, business invitees or
guests, or (iii) force majeure as described in Section 46 of this Lease,
Tenant's rental (including Base Rental and Additional Rental, as defined below)
shall abate to the extent any portion of the Premises is rendered untenantable
(for purposes

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<PAGE>   7

hereof untenantable shall include lack of HVAC services, electrical services and
elevator service which materially interferes with Tenant's enjoyment of the
Premises). In addition, notwithstanding anything to the contrary contained
herein, following such seven (7) consecutive day period (but as limited by
clauses (i), (ii) and (iii) above), Tenant shall also be entitled to pursue a
suit for specific performance and/or damages against Landlord. Notwithstanding
anything to the contrary contained herein, in the event of stoppage or
interruption of utilities or services, or the malfunction of Building
improvements (other than improvements installed by Tenant) or facilities, as
more fully described above (but as limited by clauses (i), (ii) and (iii)
above), which shall continue for seven (7) consecutive days, Tenant shall have
all rights and remedies available and provided under the laws of the State of
Washington.

       4.     ADDITIONAL RENTAL.

              (a) In addition to Base Rental, Tenant shall during the Lease
       Term, pay an amount per square foot of Rentable Space within the Premises
       ("TENANT'S ADDITIONAL RENTAL") equal to Tenant's Proportionate Share of
       the Operating Expenses. Prior to the commencement of each calendar year
       of Tenant's occupancy, Landlord may make a good faith estimate of the
       anticipated amount of Tenant's Additional Rental ("TENANT'S FORECAST
       ADDITIONAL RENTAL") and Tenant agrees to pay Tenant's Forecast Additional
       Rental in equal monthly installments in advance and without demand on the
       first day of each calendar month during and throughout the Lease Term and
       any renewal or extension thereof, subject to adjustment of Tenant's
       Forecast Additional Rental pursuant to any audit conducted pursuant to
       Paragraph 4(c) hereof.

              (b) Within one hundred fifty (150) days after the end of each
       calendar year during the Lease Term and any renewal or extension thereof,
       or as soon as reasonably possible thereafter, Landlord shall provide
       Tenant a statement showing the Operating Expenses for said calendar year
       and a statement prepared by Landlord comparing Tenant's Forecast
       Additional Rental theretofore paid by Tenant with Tenant's Additional
       Rental. In the event that Tenant's Forecast Additional Rental paid by
       Tenant exceeds Tenant's Additional Rental for said calendar year,
       Landlord, at Landlord's option, shall either pay Tenant an amount equal
       to such excess by direct payment to Tenant within thirty (30) days of the
       date of such statement, or credit such excess payment against the next
       accruing installment(s) of Tenant's Forecast Additional Rental. In the
       event that the Tenant's Additional Rental exceeds Tenant's Forecast
       Additional Rental for said calendar year, Tenant shall pay Landlord,
       within thirty (30) days of receipt of the statement, an amount equal to
       such difference. Such obligation of Landlord to refund and of Tenant to
       pay shall survive expiration or termination of this Lease. Subject to the
       right of Tenant to audit set forth in Section 4(c) below, Landlord's
       statement showing Operating Expenses shall be conclusive and binding for
       all purposes on Tenant as to any and all items contained therein to which
       Tenant has not objected in writing to Landlord within thirty (30) days
       after Tenant's receipt of such statement, which writing shall specify
       each item objected to and the detailed reason for each such objection.

              (c) Tenant at its sole expense shall have the right during the
       Lease Term, but no more frequently than once per calendar year following
       prior written notice to Landlord, to audit Landlord's books and records
       relating to Operating Expenses, or at Landlord's sole election, Landlord
       will provide at Tenant's reasonable expense a copy of such audit prepared
       by an independent certified public accountant.

              (d) The term "OPERATING EXPENSES" shall mean all costs of
       management, operation (specifically including the cost of electricity to
       the common areas of the Building and related improvements but not to any
       tenants' premises which are submetered), and maintenance of the Land, the
       Building, and all other improvements on the Land and any and all
       appurtenances thereto (the "COMMON FACILITIES"), all accrued and based on
       an annual period consisting of a calendar year. By way of illustration
       but not limitation, Operating Expenses shall include expenditures for
       maintenance and repairs not otherwise paid for by tenants; amortization
       of any capital expenditures in accordance with generally accepted
       accounting practices and principles which are incurred by Landlord to (i)
       attempt to effect a reduction in the Operating Expenses of the Building,
       or (ii) keep the Building in compliance with all applicable governmental
       rules and regulations from time to time, which the Building is not
       otherwise in compliance with; assessments and governmental charges
       (including taxes on rents or services); ad valorem property taxes with
       respect to the Land and/or the Building or any part of either thereof;
       charges for water, sewerage, and gas; cleaning, including supplies,
       janitorial services and pest control; licenses, permits and inspection
       fees; fiber connectivity and related telecommunications charges (but not
       the cost for upgrading of such for the benefit of new tenants at the
       Building after the Commencement Date); refuse collection; security
       services; insurance; costs and expenses related to the maintenance and
       operation of the Building's freight elevator, shipping and receiving
       areas, common cafeteria (or the alternative catering services described
       above), fitness facilities and conference facilities; administrative
       expenses relating to the Building, including salaries, benefits, taxes
       and other expenses for labor and management, office equipment, telephone,
       and supplies; management fees payable by Landlord with respect to the
       Land, Building and Common Facilities; fire protection; snow and ice
       removal; landscape maintenance; professional services (including legal,
       property-related consulting and accounting expenses); and security
       services. The following shall be excluded from Operating Expenses:
       depreciation; capital expenditures other than those referenced in the
       previous sentence; cost of Building alterations or renovations for other
       tenants in the Building; advertising; commissions or fees paid for
       leasing; cost of repairs occasioned by fire, windstorm, or other casualty
       (but only to the extent reimbursed by insurance proceeds); and wages,
       salaries, or other compensation paid to any executive above the grade of
       building manager; interest on debt or amortization payments on any
       mortgage or mortgages or rental under any ground or underlying leases or
       lease, if any; all services for which any tenant of the Building
       specifically reimburses Landlord or for which Tenant pays directly to
       third persons; and costs (including penalties, fines and associated legal
       expenses) incurred due to the violation by Landlord for the terms and
       conditions of the Lease, or any applicable federal, state and local

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<PAGE>   8

       governmental laws, ordinances, orders, rules and regulations, which costs
       would not have been incurred but for such violation by Landlord.

       5. ELECTRICITY. Tenant shall be solely responsible for the costs of
electrical consumption within the Premises ("ELECTRICITY") and will reimburse
Landlord on a monthly basis (at the actual cost for such service without mark-up
by Landlord following Landlord's reading of such meters) for such electrical
consumption. Without in any way limiting Tenant's responsibility for
Electricity, Tenant shall not without the express prior written consent of
Landlord use electric current in excess of the capacity of the feeders or lines
to the Building or the Premises. Tenant shall be responsible for all costs
associated with separate metering of Electricity for the Premises, including,
but not limited to, the cost of installing, maintaining, repairing and reading
the separate metering devices and subpanels. Tenant acknowledges that the cost
to provide, install and maintain submeters shall be at Tenant's sole expense.

       6. PAYMENTS AND PERFORMANCE. Tenant agrees to pay all rents and sums
provided to be paid by Tenant hereunder at the times and in the manner herein
provided, without any setoff, deduction or counterclaim whatsoever except as may
otherwise be provided in Section 3 above. Should this Lease commence on a day
other than the first day of a calendar month or terminate on a day other than
the last day of a calendar month, the rent for such partial month shall be
proportionately reduced. The Base Rental for the first partial month, if any,
shall be payable at the beginning of said period or as Prepaid Rental. The
obligation of Tenant to pay such rent is an independent covenant, and except as
provided in Section 3 above, no act or circumstance whatsoever, whether such act
or circumstance constitutes a breach of covenant by Landlord or not, shall
release Tenant from the obligation to pay rent. Time is of the essence in the
performance of all of Tenant's and Landlord's obligations hereunder. Any amount
that becomes owing by Tenant to Landlord hereunder shall bear interest at the
rate of 15% per annum from the due date until paid. In addition, at Landlord's
option, but only to the extent allowed by applicable law and not in excess of
the amount allowed by applicable law, Tenant shall pay a late charge in the
amount (as solely determined by Landlord) of five percent (5%) of any
installment of rental hereunder which is not paid within five (5) days of the
date on which it is due in order to compensate Landlord for the additional
expense involved in handling delinquent payments.

       7. TENANT PLANS AND SPECIFICATIONS - INSTALLATION OF IMPROVEMENTS. Tenant
shall install or cause to be installed in the Premises substantially all of the
improvements shown on the Approved Working Drawings (as defined in Exhibit "D"
attached hereto) upon the terms and conditions set forth in the Leasehold
Improvements Agreement attached hereto as Exhibit "D" and made a part hereof
(subject, however, to the change order provisions set forth therein).

       8. COMPLETION OF IMPROVEMENTS AND COMMENCEMENT OF RENT. By moving into
the Premises or taking possession thereof, Tenant accepts the Premises as
suitable for the purposes for which the same are leased and accepts the Building
and every appurtenance thereof, and waives any and all defects therein (other
than latent defects) and on request from Landlord, Tenant shall promptly execute
and deliver to Landlord an Acceptance of Premises Memorandum in the form
attached hereto as Exhibit "E" and made a part hereof for all purposes.

       9. RELOCATION OF PREMISES. [Intentionally Deleted]

       10. REPAIRS AND REENTRY. Tenant will, at Tenant's own cost and expense,
maintain and keep the Premises and any alterations and additions thereto in
sound condition and good repair, and shall pay for the repair of any damage or
injury done to the Building or any part thereof (not otherwise covered by the
property insurance to be maintained by Landlord on the Building, excluding
Tenant's Premises) by Tenant or Tenant's agents, employees and invitees;
provided, however, that Tenant shall make no repairs to the Premises without the
prior written consent of Landlord, which consent shall not be unreasonably
withheld, conditioned or delayed. Notwithstanding the foregoing, in the event
Landlord's property insurance is used to repair any damage or injury done to the
Building (excluding Tenant's Premises for which Tenant's property insurance
shall be used) by Tenant or Tenant's agents, employees and invitees, Tenant
shall (i) pay the deductible associated with such repairs, (ii) pay all amounts
in excess of insurance proceeds available for such repairs, and (iii) pay for
any increase Landlord incurs in its premium for such coverage as a direct result
of insurance proceeds being used to fund Tenant's repair obligations. The
performance by Tenant of its obligation to maintain and make repairs shall be
conducted only by contractors approved by Landlord after plans and
specifications therefor have been approved by Landlord. Tenant will not commit
or allow any waste or damage to be committed on any portion of the Premises, and
upon the termination of this Lease by lapse of time or otherwise, Tenant shall
deliver up the Premises to Landlord in as good condition as at date of
possession, ordinary wear and tear excepted. Upon such termination of this
Lease, Landlord shall have the right to reenter and resume possession of the
Premises. Notwithstanding the foregoing provisions of this Paragraph 10, any
repairs to the Premises or the Building that are necessitated because of any
damage caused by fire or other casualty shall be governed by the provisions of
Paragraph 22 below. Landlord shall be responsible for maintenance to the
exterior, structural and Common Areas of the Building (e.g., the structural
roof, roof membrane, walls and foundation and utilities serving the Building
and/or located outside Tenant's Premises). Notwithstanding the foregoing,
Landlord may, as provided in Section 4(d) of this Lease, include the cost of
normal repair and maintenance items in the Building's Operating Expenses and
shall be reimbursed for same to the extent of Tenant's Proportionate Share.
Landlord represents and warrants that to the best of its knowledge as of the
date hereof, all Building systems (i.e., HVAC system, elevators, electrical
system, plumbing system, fire prevention system), structural components of the
Building, roofs and foundations are in good working order as of the Commencement
Date of this Lease.

       11. ASSIGNMENT AND SUBLETTING. In the event that Tenant desires to
encumber this Lease, assign this Lease or sublet all or any part of the Premises
or grant any license, concession or other right of occupancy of any portion of
the Premises, Tenant shall notify Landlord in writing and shall state the name
of the proposed assignee, sublessee or other transferee and the terms of the
proposed assignment, sublease or transfer. Tenant shall also

                                       7
<PAGE>   9

provide financial information and state and provide information requested by
Landlord as to the nature and character of the business of the proposed
assignee, sublessee or transferee. Tenant shall not assign or mortgage this
Lease or any right hereunder or interest herein, and Tenant shall not sublet the
Premises in whole or in part or grant any license, concession or other right of
occupancy of any portion of the Premises, without the prior written consent of
Landlord, which consent shall not be unreasonably withheld, delayed or
conditioned based upon Landlord's reasonable determination of the
creditworthiness and nature and character of the business of the proposed
assignee, sublessee or transferee. Any such assignment, mortgage or subletting
without such consent shall be void and shall, at the sole option of Landlord, be
deemed an event of default by Tenant under this Lease. Notwithstanding any
assignment or subletting consented to by Landlord, Tenant and any guarantor of
Tenant's obligations under this Lease and each assignee shall at all times
remain jointly and severally fully responsible and liable for the payment of the
rent herein specified and for compliance with all of Tenant's other covenants
and obligations under this Lease. No consent to any assignment or mortgage of
this Lease or any subletting of the Premises shall constitute a waiver of the
provisions of this Paragraph except as to the specific instance covered thereby.
In the event that the monthly rental per square foot of space subleased which is
payable by any sublessee to Tenant shall exceed the monthly rental per square
foot for the same space payable for the same month by Tenant to Landlord
(including any bonuses or any other consideration paid directly or indirectly by
the sublessee to Tenant), Tenant shall be obligated to pay fifty percent (50%)
of the amount of such excess to Landlord as additional rent hereunder within
five (5) days of the date it is received by Tenant from the sublessee. In the
event Tenant shall receive any consideration from an assignee other than the
assumption by the assignee of Tenant's obligations hereunder, Tenant shall be
obligated to pay fifty percent (50%) of the amount of such consideration to
Landlord as additional rent hereunder on the same date it is received by Tenant.
Landlord, at Landlord's option, may elect to require that rental payable by any
sublessee be paid directly to Landlord and offset Tenant's rent obligations
accordingly. At no time during the Lease Term shall Tenant be entitled to (i)
advertise the Premises for sublease without the prior written consent of
Landlord, such consent not to be unreasonably withheld, (ii) market the Premises
for sublease to another tenant of the Building or person or entity with whom
Landlord is negotiating to lease space in the Building, and (iii) market the
Premises for sublease at a rate less than the fair market value of the Premises.
Any transfer by operation of law shall also constitute an assignment prohibited
by this Paragraph 11. Tenant shall reimburse Landlord, on demand, for its
reasonable attorneys' fees and other expenses incurred in connection with
considering any request for Landlord's consent to an assignment or sublease of
the Premises.

       Notwithstanding anything to the contrary hereinabove, Tenant may assign
or sublet the Premises to a subsidiary or affiliate under common ownership or
control of Tenant, or to any entity merging with or into Tenant (collectively,
"Affiliated Assignment"), without any further action by Landlord and such action
shall be deemed a permitted assignment or subletting subject to the provisions
hereunder so long as (i) the original Tenant and the transferee tenant shall be
jointly and severally liable for the performance of the Lease obligations and
(ii) the Permitted Use, creditworthiness and business character of the
transferee tenant following such transfer or merger is comparable with Tenant's
use, business character and creditworthiness prior to such transfer or merger.
In addition, the following types of transactions shall not be deemed assignments
or transfers for purposes of this Paragraph 11 for which Landlord's prior
written consent must be obtained; provided, however, that the limitations set
forth in clauses (i) and (ii) above shall still be applicable: (a) the sale or
issuance of stock or other securities of the Tenant to a new investor or
investors, even if such sales or issuance results in a change of control and/or
a change in management; (b) the sale or other transfer by Tenant's present
parent corporation of all or any portion of the stock of Tenant, even if such
sale or transfer results in a change of control and/or a change in management;
or (c) the sale or issuance of stock or other securities of the Tenant in a
public offering or as a part of a private placement to raise additional capital
or create liquidity for investors.

       12. ALTERATIONS AND ADDITIONS BY TENANT. Tenant shall make no alterations
in or additions to the Premises without the prior written consent of Landlord
which shall not be unreasonably withheld, conditioned or delayed. All
alterations, additions, and improvements made to or fixtures or improvements
placed in or upon the Premises by either party (except only moveable trade
fixtures of Tenant) if not otherwise identified within thirty (30) days of
installation by Tenant as removable upon execution of the Lease (or otherwise
required to be removed by Landlord as a condition to its consent to such
alteration or addition) shall be deemed a part of the Building and the property
of Landlord at the time they are placed in or upon the Premises, and they shall
remain upon and be surrendered with the Premises as a part thereof at the
termination of this Lease, unless Landlord shall elect otherwise, whether such
termination shall occur by the lapse of time or otherwise. In the event Landlord
shall elect that certain alterations, additions and improvements made by Tenant
in the Premises shall be removed by Tenant, Tenant shall remove them and Tenant
shall restore the Premises to its original condition, at Tenant's own cost and
expense, prior to the termination of the Lease Term. Alterations and additions
to the Premises will be performed by Landlord (unless otherwise designated by
Landlord) at Tenant's cost and expense. Tenant acknowledges that Landlord's
approval of any alterations or additions shall not be a representation by
Landlord that such alterations, additions or improvements comply with applicable
laws. The initial alterations and additions to the Premises by Tenant shall be
controlled by the terms and conditions of the Leasehold Improvements Agreement
attached hereto. In connection with such initial improvements, Tenant shall have
the right to pursue Landlord's permission to construct certain special
installations as more particularly described in Paragraph 56 below.

       13. LEGAL USE; VIOLATIONS OF INSURANCE COVERAGE; NUISANCE. Tenant will
not occupy or use any portion of the Premises for any purpose other than the
Sole Permitted Use or for any purpose which is unlawful or which, in the
reasonable judgment of Landlord, is unduly hazardous due to risk of fire,
explosion or other casualty, nor permit anything to be done which will in any
way (i) increase the rate of fire and casualty insurance on the Building or its
contents, or (ii) create unreasonable elevator loads or otherwise interfere with
standard Building operations, or (iii) affect the structural integrity or design
capabilities of the Building or (iv) result in the storage of any hazardous
materials or substances at the Building except as permitted by law and the
express terms and conditions of this Lease. In the event that, by reason of any
act or conduct of business of Tenant, there shall be any increase in the rate of
insurance on the Building or its contents created by Tenant's acts or conduct of
business, then

                                       8
<PAGE>   10

Tenant hereby agrees to pay Landlord the amount of such increase on demand.
Tenant shall not erect, place, or allow to be placed any sign, advertising
matter, stand, booth or showcase in, upon or visible from the vestibules, halls,
corridors, doors, outside walls, outside windows or pavement of the Building or
the Land without the prior written consent of Landlord. Tenant will conduct its
business, and use commercially reasonable efforts to control its agents,
employees, and invitees in such a manner as not to create any nuisance or
interfere with, materially annoy or disturb other tenants or Landlord in the
management of the Building.

       14. LAWS AND REGULATIONS. Tenant at its sole expense will maintain the
Premises in a clean, safe and healthful condition and will comply with all laws,
ordinances, orders, rules and regulations of any governmental authority having
jurisdiction over the use, conditions or occupancy of the Premises.

       15. INDEMNITY, LIABILITY AND LOSS OR DAMAGE.

       (a) Landlord shall not be liable to Tenant or Tenant's agents, employees,
contractors, guests, invitees or any person claiming by, through or under Tenant
for any injury to person, loss of or damage to property, or for loss of or
damage to Tenant's business, occasioned by or through the acts or omissions of
Landlord, or by any cause whatsoever except to the extent arising from or out of
Landlord's negligence or willful wrongdoing. Except to the extent arising from
or out of Landlord's negligence or willful wrongdoing, Landlord shall not be
liable for, and Tenant shall defend and indemnify Landlord and save it harmless
from, all suits, actions, damages, liability and expense in connection with loss
of life, bodily or personal injury or property damage arising from or out of any
occurrence in, upon, at or from the Premises (except for any pre-existing
circumstances, conditions or occurrences in the Premises) or the occupancy or
use by Tenant of the Premises or any part thereof, or occasioned wholly or in
part by any action or omission of Tenant, its agents, contractors, employees,
invitees, or licensees. If Landlord shall be made a party to any action
commenced by or against Tenant, Tenant shall protect and hold Landlord harmless
therefrom and on demand shall pay all costs, expenses, and reasonable attorney's
fees incurred by Landlord in connection therewith. The indemnification
obligations contained in this Paragraph 15 shall not be limited by any worker's
compensation, benefit or disability laws, and each indemnifying party hereby
waives any immunity that said party may have under the Washington Industrial
Insurance Act, Title 51 RCW, and similar worker's compensation, benefit or
disability laws. LANDLORD AND TENANT ACKNOWLEDGE BY THEIR EXECUTION OF THIS
LEASE THAT EACH INDEMNIFICATION PROVISION OF THIS LEASE (INCLUDING, BUT LIMITED
TO, THOSE RELATING TO WORKER'S COMPENSATION, BENEFITS AND LAWS) WAS SPECIFICALLY
NEGOTIATED AND AGREED TO BY LANDLORD AND TENANT).

       (b) Tenant shall not be liable to Landlord or Landlord's agents,
employees, contractors, guests, invitees or any person claiming by, through or
under Landlord for any injury to person, loss of or damage to property, or for
loss of or damage to Landlord's business, occasioned by or through the acts or
omissions of Tenant, or by any cause whatsoever except to the extent arising
from or out of Tenant's negligence or willful wrongdoing. Except to the extent
arising from or out of Tenant's negligence or willful wrongdoing, Tenant shall
not be liable for, and Landlord shall defend and indemnify Tenant and save it
harmless from, all suits, actions, damages, liability and expense in connection
with loss of life, bodily or personal injury or property damage arising from or
out of any occurrence in, upon, at or from the Premises or the Building or any
part thereof, or occasioned wholly or in part by any action or omission of
Landlord, its agents, contractors, employees, invitees, or licensees. If Tenant
shall be made a party to any action commenced by or against Landlord, Landlord
shall protect and hold Tenant harmless therefrom and on demand shall pay all
costs, expenses, and reasonable attorney's fees incurred by Tenant in connection
therewith. The indemnification obligations contained in this Paragraph 15 shall
not be limited by any worker's compensation, benefit or disability laws, and
each indemnifying party hereby waives any immunity that said party may have
under the Washington Industrial Insurance Act, Title 51 RCW, and similar
worker's compensation, benefit or disability laws. LANDLORD AND TENANT
ACKNOWLEDGE BY THEIR EXECUTION OF THIS LEASE THAT EACH INDEMNIFICATION PROVISION
OF THIS LEASE (INCLUDING, BUT LIMITED TO, THOSE RELATING TO WORKER'S
COMPENSATION, BENEFITS AND LAWS) WAS SPECIFICALLY NEGOTIATED AND AGREED TO BY
LANDLORD AND TENANT).

       16. RULES OF THE BUILDING. Tenant will comply fully, and will use
reasonable efforts to cause Tenant's agents, employees, and invitees to comply
fully with all Rules and Regulations of the Building which are attached hereto
as Exhibit "F" and made a part hereof as though fully set out herein. As more
particularly provided therein, Landlord shall at all times have the right to
change such Rules and Regulations or to amend them in such reasonable manner as
Landlord may deem advisable for the safety, protection, care and cleanliness of
the Building and appurtenances and for preservation of good order therein, all
of which Rules and Regulations, changes and amendments will be forwarded to
Tenant in writing and shall be complied with and observed by Tenant and Tenant's
agents, contractors, employees and invitees.

       17. ENTRY FOR REPAIRS AND INSPECTION. Landlord and its agents and
representatives shall have the right following 24 hours prior notice to enter
into and upon any and all parts of the Premises at all reasonable hours (or, in
an emergency, at any hour without prior notice) to inspect same or clean or make
repairs or alterations or additions to the Building and the Premises (whether
structural or otherwise) as Landlord may deem necessary, and during the
continuance of any such work, Landlord may temporarily close doors, entryways,
public spaces and corridors and interrupt or temporarily suspend Building
services and facilities, and subject to the terms and conditions of Paragraph 3
above, Tenant shall not be entitled to any abatement or reduction of rent by
reason thereof. During the Lease Term, Landlord may exhibit the Premises to
prospective purchasers and lenders at reasonable hours and upon 24 hours' prior
notice to Tenant. Furthermore, during the one-year period prior to the
expiration date of this Lease, Landlord and Landlord's agents may exhibit the
Premises to prospective tenants during Normal Business Hours and upon 24 hours'
prior notice to Tenant.

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<PAGE>   11

       18. CONDEMNATION. If all of the Premises, or so much thereof as would
materially interfere with Tenant's use of the remainder, shall be taken or
condemned for any public use or purpose by right of eminent domain, with or
without litigation, or be transferred by agreement in connection with or in lieu
of or under threat of condemnation, then the Lease Term and the leasehold estate
created hereby shall terminate as of the date title shall vest in the condemnor
or transferee. If all or any portion of the Building or a material portion of
the Land required for the Building's operation is taken or condemned or
transferred as aforesaid, Landlord or Tenant shall have the option to terminate
this Lease effective as of the date title shall vest in the condemnor or
transferee. Landlord shall receive the entire award from any taking or
condemnation (or the entire compensation paid because of any transfer by
agreement), and Tenant shall have no claim thereto; provided, however, Tenant
shall be entitled to recover in a separate action against such condemning
authority, an award for relocation benefits, if any, and an award with respect
to Tenant's above Building standard finish-out at the Premises.

       19. LANDLORD'S LIEN AND SECURITY INTEREST. Landlord shall not have a
landlord's lien of any kind under this Lease.

       20. ABANDONED PROPERTY. All personal property of Tenant remaining in the
Premises later than ten (10) days after the termination or expiration of the
Lease Term or after the abandonment of the Premises by Tenant may be treated by
Landlord as having been abandoned by Tenant and Landlord may, at its option and
election, thereafter take possession of such property and either (i) declare
same to be the property of Landlord, or (ii) at the cost and expense of Tenant,
store and/or dispose of such property in any manner and for whatever
consideration that Landlord, in its sole discretion, shall deem advisable.
Except as otherwise provided in a prior notification from Tenant to Landlord
providing a reasonable explanation that Tenant is not abandoning the Premises,
Tenant shall be presumed conclusively to have abandoned the Premises if the
amount of Tenant's property removed by Tenant from the Premises is substantial
enough to indicate a probable intent to abandon the Premises and such removal is
not in the normal course of Tenant's business, or if Tenant removes any material
amount of Tenant's personal property from the Premises at a time when Tenant is
in default in the payment of rental due hereunder or in the performance of any
other obligation of Tenant hereunder and such removal is not in the normal
course of Tenant's business.

       21. HOLDING OVER. Should Tenant continue to hold the Premises after this
Lease terminates, whether by lapse of time or otherwise, such holding over
shall, unless otherwise agreed by Landlord in writing, constitute and be
construed as a tenancy from month to month at a rental equal to the greater of
(i) 150% of the amount of the monthly rental payable during the last month prior
to the termination of this Lease or (ii) 150% of the rate for which similar
space in the Building is then being leased by Landlord, and upon and subject to
all of the other terms and provisions set forth herein except any right to renew
this Lease, expand the Premises or lease additional space. This provision shall
not be construed, however, as permission by Landlord for Tenant to holdover. No
payments of money by Tenant to Landlord after the termination of this Lease
shall reinstate, continue, or extend the Lease Term and no extension of this
Lease after the termination hereof shall be valid unless and until the same
shall be reduced to writing and signed by both Landlord and Tenant. Tenant shall
be liable to Landlord for all damage which Landlord shall suffer by reason of
any holding over by Tenant, and Tenant shall indemnify and hold Landlord
harmless against all claims made by any other tenant or prospective tenant
against Landlord resulting from delay by Landlord in delivering possession of
the Premises (or any portion thereof) to such other tenant or prospective
tenant.

       22. FIRE AND CASUALTY.

              (a) If the Premises are damaged by fire or other casualty and if
       such damage is not susceptible of repair within two hundred seventy (270)
       days (as estimated, as soon as reasonably practicable after the
       occurrence of such damage, by an architect of recognized good reputation
       selected by Landlord), then in such event this Lease, at the option of
       either Landlord or Tenant, exercised by giving written notice thereof to
       the other within thirty (30) days after receipt of such written estimate
       of the architect so selected, shall terminate as of the date of such
       loss, and Tenant shall pay the rent hereunder apportioned to the time of
       such loss and shall pay all other obligations of Tenant owing on the date
       of termination, and Tenant shall have no longer than thirty (30) days in
       which to surrender the Premises to Landlord.

              (b) If the damage described above is susceptible of repair within
       two hundred seventy (270) days, or if the damage is not susceptible of
       repair within two hundred seventy (270) days but Landlord and Tenant fail
       to exercise the option to terminate this Lease, and so long as Landlord
       does not elect to terminate this Lease pursuant to Subparagraph (c)
       below, Landlord shall enter and make the necessary repairs without
       affecting this Lease, but the rent hereunder shall be reduced or abated
       as shall be equitable, in the good faith judgment of Landlord, until such
       repairs are made, unless such damage has been so slight that Tenant's
       occupancy of the Premises is not materially interfered with, in which
       case the rent hereunder shall not be abated or reduced. Notwithstanding
       the foregoing, Landlord shall have the option to terminate this Lease and
       shall not be obligated to repair the Premises or the Building if the
       damage is not covered by insurance or if Landlord's mortgagee applies any
       portion of the insurance proceeds to the unpaid balance of its loan.

              (c) In the event the Building is so badly damaged or injured by
       fire or other casualty, even though the Premises may not be affected,
       that Landlord decides, within ninety (90) days after such damage, not to
       rebuild or repair the Building (such decision being vested exclusively in
       the discretion of Landlord), then in such event Landlord shall so notify
       Tenant in writing and this Lease shall terminate as of the date specified
       for termination in the notice from Landlord to Tenant, and Tenant shall
       pay rent hereunder apportioned to the date of such termination and shall
       pay all other obligations of Tenant owing on the date of termination, and
       Tenant shall have no longer than thirty (30) days in which to surrender
       the Premises to Landlord.

                                       10
<PAGE>   12

              (d) Notwithstanding the foregoing provisions of this Paragraph 22,
       Tenant agrees that if the Premises or any other portion of the Building
       is damaged by fire or other casualty resulting from the fault or
       negligence of Tenant or any of its agents, employees, or invitees, then
       the cost of restoring the property damage in excess of the policy limits
       of the property insurance proceeds which Landlord is required to maintain
       under this Lease shall be paid by Tenant within thirty (30) days
       following demand, and there shall be no abatement of rent before or
       during the repair of such damage.

       23. ENTIRE AGREEMENT AND AMENDMENT; NO REPRESENTATIONS OR WARRANTIES; NO
MEMORANDUM OF LEASE. This Lease contains the entire agreement between the
parties hereto with respect to the subject matter hereof and supersedes any and
all prior and contemporaneous agreements, understandings, promises, and
representations made by either party to the other concerning the subject matter
hereof and the terms applicable hereto. It is expressly agreed by Tenant, as a
material consideration to Landlord for the execution of this Lease, that there
have been no representations, understandings, stipulations, agreements or
promises pertaining to the Premises, the Building or this Lease not incorporated
in writing herein. This Lease shall not be altered, waived, amended or extended,
except by a written agreement signed by the parties hereto, unless otherwise
expressly provided herein. LANDLORD'S DUTIES AND WARRANTIES ARE LIMITED TO THOSE
SET FORTH IN THIS LEASE, AND SHALL NOT INCLUDE ANY IMPLIED DUTIES OR WARRANTIES,
ALL OF WHICH ARE HEREBY DISCLAIMED BY LANDLORD AND WAIVED BY TENANT. LANDLORD
AND TENANT EXPRESSLY DISCLAIM ANY IMPLIED WARRANTY THAT THE PREMISES ARE
SUITABLE FOR TENANT'S INTENDED COMMERCIAL PURPOSE, AND EXCEPT AS OTHERWISE
PROVIDED IN PARAGRAPH 3, TENANT'S OBLIGATION TO PAY RENT HEREUNDER IS NOT
DEPENDENT UPON THE CONDITION OF THE PREMISES OR THE PERFORMANCE BY LANDLORD OF
ITS OBLIGATIONS HEREUNDER, AND, EXCEPT AS OTHERWISE EXPRESSLY PROVIDED HEREIN,
TENANT SHALL CONTINUE TO PAY THE RENT, WITHOUT ABATEMENT, SETOFF OR DEDUCTION,
NOTWITHSTANDING ANY BREACH BY LANDLORD OF ITS DUTIES OR OBLIGATIONS HEREUNDER,
WHETHER EXPRESS OR IMPLIED. Neither this Lease nor a memorandum of this Lease
shall be recorded in the public records of the county in which the Building is
located without the prior written consent of Landlord, which may be withheld in
Landlord's sole discretion. Notwithstanding anything to the contrary set forth
in this Paragraph 23, Landlord hereby represents and warrants to Tenant as
follows: (a) Landlord has fee simple title to the Land and the Building, (b)
Landlord has been duly authorized to enter into this Lease, and (c) the persons
signing this Lease on Landlord's behalf have been duly authorized to do so by
appropriate resolution and consent.

       24. TRANSFER OF LANDLORD'S RIGHTS. In the event Landlord transfers its
interest in the Building, Landlord shall thereby automatically be released from
any further obligations hereunder if Landlord transfers the Security Deposit to
such transferee and such transferee agrees to expressly assume all obligations
of Landlord hereunder, and Tenant agrees to look solely to the successor in
interest of Landlord for the performance of such obligations.

       25. DEFAULT.

              (a) The following events shall be deemed to be events of default
       (herein so called) by Tenant under this Lease:

                     (i) Tenant shall fail to pay any rental or other sum
              payable by Tenant hereunder as and when such rental or other sum
              becomes due and payable; provided, however, that Tenant shall be
              entitled to receive, three (3) times each calendar year, a written
              notice of such failure from Landlord and a five (5) day period
              thereafter to cure such payment default;

                     (ii) Tenant shall fail to comply with any other provision,
              condition or covenant of this Lease and any such failure is not
              cured within thirty (30) days after Landlord gives written notice
              of such failure to Tenant; provided, however, Tenant shall not be
              deemed to have failed to comply hereunder if such default cannot
              be cured within said thirty (30) days and Tenant is diligently
              proceeding to do so;

                     (iii) Tenant shall desert or vacate any substantial portion
              of the Premises;

                     (iv) Tenant shall assign this Lease or sublet all or any
              part of the Premises or grant any license, concession or other
              right of occupancy of any portion of the Premises, without the
              prior written consent of Landlord except as permitted by the terms
              of Paragraph 11 of this Lease;

                     (v) Any petition shall be filed by or against Tenant or any
              guarantor of Tenant's obligations under this Lease pursuant to any
              section or chapter of the present federal Bankruptcy Act or under
              any future federal Bankruptcy Act or under any similar law or
              statute of the United States or any state thereof (which as to any
              involuntary petition shall not be and remain discharged or stayed
              within a period of thirty (30) days after its entry), or Tenant or
              any guarantor of Tenant's obligations under this Lease shall be
              adjudged bankrupt or insolvent in proceedings filed under any
              section or chapter of the present federal Bankruptcy Act or under
              any future federal bankruptcy act or under any similar law or
              statute of the United States or any state thereof;

                     (vi) Tenant or any guarantor of Tenant's obligations under
              this Lease shall become insolvent or make a transfer in fraud of
              creditors;

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<PAGE>   13

                     (vii) Tenant or any guarantor of this Lease shall make an
              assignment for the benefit of creditors; or

                     (viii) A receiver or trustee shall be appointed for Tenant
              or any guarantor of this Lease or for any of the assets of Tenant
              or any guarantor of this Lease.

              (b) Upon the occurrence of any event of default, Landlord shall
       have the option to do any one or more of the following without any
       further notice or demand, in addition to and not in limitation of any
       other remedy permitted by law or by this Lease:

                     (i) Enforce, by all legal suits and other means (including
              both judicial and non-judicial means to the extent provided under
              applicable Washington law), its rights hereunder, including the
              collection of Base Rental, Tenant's Additional Rental and other
              sums payable by Tenant hereunder and the reimbursement for all
              unamortized tenant allowances and concessions, without reentering
              or resuming possession of the Premises and without terminating
              this Lease.

                     (ii) Terminate this Lease by issuing written notice of
              termination to Tenant, in which event Tenant shall immediately
              surrender the Premises to Landlord, but if Tenant shall fail to do
              so, Landlord may without notice and without prejudice to any other
              remedy Landlord may have, enter upon and take possession of the
              Premises and expel or remove Tenant and its effects without being
              liable to prosecution or any claim for damages therefor, and upon
              any such termination, Tenant agrees that in addition to its
              liability for the payment of arrearages of Base Rental, Tenant's
              Additional Rental and other sums due and owing by Tenant to
              Landlord under this Lease upon such termination, Tenant shall be
              liable to Landlord for damages. Tenant shall pay to Landlord as
              damages on the same days as Base Rental, Tenant's Additional
              Rental and other payments which are expressed to be due under the
              provisions of this Lease, the total amount of such Base Rental,
              Tenant's Additional Rental and other payments, less such part, if
              any, of such payments that Landlord shall have been able to
              collect from a new tenant upon reletting; provided, however, that
              Landlord shall have an obligation to use commercially reasonable
              efforts to relet the Premises so as to mitigate the amount for
              which Tenant is liable provided such mitigation efforts would not
              have a material adverse effect on Landlord's marketing of other
              space in the Building. Landlord shall have the right at any time
              to accelerate rent and demand final settlement. Upon demand for a
              final settlement, Landlord shall have the right to receive, and
              Tenant hereby agrees to pay, as damages for Tenant's breach, the
              difference between the total rental provided for in this Lease for
              the remainder of the Lease Term and the reasonable rental value of
              the Premises for such period, such difference to be discounted to
              present value at a rate equal to the rate of interest allowed by
              law (at the time the demand for final settlement is made) when the
              parties to a contract have not agreed on any particular rate of
              interest (or, in the absence of such law, at the rate of 6% per
              annum).

                     (iii) Enter upon and take possession of the Premises
              without terminating this Lease and expel or remove Tenant and its
              effects therefrom without being liable to prosecution or any claim
              for damages therefor, and Landlord may relet the Premises for the
              account of Tenant. Tenant shall pay to Landlord all arrearages of
              Base Rental, Tenant's Additional Rental and other sums due and
              owing by Tenant to Landlord, and Tenant shall also pay to Landlord
              during each month of the unexpired Lease Term the installments of
              Base Rental, Tenant's Additional Rental and other sums due
              hereunder, less such part, if any, that Landlord shall have been
              able to collect from a new tenant upon reletting; provided,
              however, that Landlord shall have no obligation to relet the
              Premises so as to mitigate the amount for which Tenant is liable.
              In the event Landlord exercises the rights and remedies afforded
              to it under this Paragraph 25(b)(iii) and then subsequently elects
              to terminate this Lease, Tenant shall be liable to Landlord for
              damages as set forth in Paragraph 25(b)(ii) above and Landlord
              shall have the right at any time to demand final settlement as
              provided therein.

                     (iv) Landlord may do whatever Tenant is obligated to do by
              the provisions of this Lease and may enter the Premises in order
              to accomplish this purpose. Tenant agrees to reimburse Landlord
              immediately upon demand for any expenses which Landlord may incur
              in its actions pursuant to this Subparagraph, and Tenant further
              agrees that Landlord shall not be liable for damages resulting to
              Tenant from such action, whether caused by the negligence of
              Landlord or otherwise.

       Pursuit of any of the foregoing remedies shall not preclude pursuit of
       any of the other remedies herein provided or any other remedies provided
       by law or equity. Any entry by Landlord upon the Premises may be by use
       of a master or duplicate key or electronic pass card or any locksmith's
       entry procedure or other means. Any reletting by Landlord shall be
       without notice to Tenant, and if Landlord has not terminated this Lease,
       the reletting may be in the name of Tenant or Landlord, as Landlord shall
       elect. Any reletting shall be for such term or terms (which may be
       greater or less than the period which, in the absence of a termination of
       this Lease, would otherwise constitute the balance of the Lease Term) and
       on such terms and conditions (which may include free rent, rental
       concessions or tenant inducements of any nature) as Landlord in its
       absolute discretion may determine, and Landlord may collect and receive
       any rents payable by reason of such reletting. In the event of any
       reletting, Tenant shall pay to Landlord on demand the cost of renovating,
       repairing and altering the Premises for a new tenant or tenants, and the
       cost of advertisements, brokerage fees, reasonable attorneys' fees and
       other costs and expenses incurred by Landlord in connection with such
       reletting. In the event any rentals actually collected by Landlord upon

                                       12
<PAGE>   14

       any such reletting for any calendar month are in excess of the amount of
       rental payable by Tenant under this Lease for the same calendar month,
       the amount of such excess shall belong solely to Landlord and Tenant
       shall have no right with respect thereto. In the event it is necessary
       for Landlord to institute suit against Tenant in order to collect the
       rental due hereunder or any deficiency between the rental provided for by
       this Lease for a calendar month and the rental actually collected by
       Landlord for such calendar month, Landlord shall have the right to allow
       such deficiency to accumulate and to bring an action upon several or all
       of such rental deficiencies at one time. No suit shall prejudice in any
       way the right of Landlord to bring a similar action for any subsequent
       rental deficiency or deficiencies.

       26. WAIVER; ATTORNEY'S FEES. No act or thing done by Landlord or its
agents during the Lease Term shall be deemed an acceptance of an attempted
surrender of the Premises, and no agreement to accept a surrender of the
Premises shall be valid unless made in writing and signed by Landlord. No
reentry or taking possession of the Premises by Landlord shall be construed as
an election on its part to terminate this Lease, unless a written notice of such
intention, signed by Landlord, is given by Landlord to Tenant. Notwithstanding
any such reletting or reentry or taking possession, Landlord may at any time
thereafter elect to terminate this Lease for a previous event of default.
Landlord's acceptance of rent following an event of default hereunder shall not
be construed as Landlord's waiver of such event of default. No waiver by
Landlord or Tenant of any violation or breach of any of the terms, provisions
and covenants herein contained shall be deemed or construed to constitute a
waiver of any other violation or breach of any of the terms, provisions and
covenants herein contained. Forbearance by Landlord to enforce one or more of
the remedies herein provided upon an event of default shall not be deemed or
construed to constitute a waiver of any other violation or default. The failure
of Landlord to enforce any of the Rules and Regulations described in Paragraph
16 against Tenant or any other tenant in the Building shall not be deemed a
waiver of any such Rules and Regulations. No provision of this Lease shall be
deemed to have been waived by Landlord unless such waiver is in writing and is
signed by Landlord. The rights granted to Landlord and Tenant in this Lease
shall be cumulative of every other right or remedy which Landlord of Tenant may
otherwise have at law or in equity, and the exercise of one or more rights or
remedies shall not prejudice or impair the concurrent or subsequent exercise of
other rights or remedies. If either Landlord or Tenant brings any action under
this Lease, or consults or places this Lease or any amount payable by the other
party hereunder with an attorney for the enforcement of any of either party's
rights hereunder, then the non-prevailing party agrees to pay to the prevailing
party, on demand, the reasonable attorneys' fees and other costs and expenses
incurred by such prevailing party in connection therewith.

       27. QUIET POSSESSION. Landlord hereby covenants that Tenant, upon paying
rent as herein reserved, and performing all covenants and agreements herein
contained on the part of Tenant, shall and may peacefully and quietly have, hold
and enjoy the Premises without any disturbance from Landlord or from any other
person claiming by, through or under Landlord, subject to the terms, provisions,
covenants, agreements and conditions of this Lease, specifically including, but
without limitation, the matters described in Paragraph 34 hereof.

       28. SEVERABILITY. If any clause or provision of this Lease is illegal,
invalid or unenforceable under present or future laws effective during the Lease
Term, then and in that event, it is the intention of the parties hereto that the
remainder of this Lease shall not be affected thereby, and it is also the
intention of the parties to this Lease that in lieu of each clause or provision
that is illegal, invalid or unenforceable, there be added as a part of this
Lease a clause or provision as similar in terms to such illegal, invalid or
unenforceable clause or provision as may be possible and be legal, valid and
enforceable.

       29. SECURITY DEPOSIT. The Security Deposit shall be held by Landlord
without liability for interest and as security for the performance by Tenant of
Tenant's covenants and obligations under this Lease, it being expressly
understood that the Security Deposit shall not be considered an advance payment
of rental or a measure of Landlord's damages in case of default by Tenant upon
the occurrence of any event of default by Tenant or upon termination of this
Lease. Landlord may commingle the Security Deposit with other funds. Landlord
may, from time to time, without prejudice to any other remedy, use the Security
Deposit to the extent necessary to make good any arrearages of rent or to
satisfy any other covenant or obligation of Tenant hereunder. Following any such
application of the Security Deposit, Tenant shall pay to Landlord on demand the
amount so applied in order to restore the Security Deposit to its original
amount. At the termination of this Lease, the balance of the Security Deposit
remaining after any such application (including any amount necessary to
reasonably cure a Tenant default) shall be returned by Landlord to Tenant within
thirty (30) days following the expiration of the Lease Term. If Landlord
transfers its interest in the Premises during the Lease Term, Landlord shall
assign the Security Deposit to the transferee who expressly assumes this Lease
and thereafter shall have no further liability for the return of, or any other
matter relating to, such Security Deposit.

       30. NO SUBROGATION; INSURANCE.

              (a) Tenant hereby waives any cause of action it might have against
       Landlord on account of any loss or damage that is insured against under
       any insurance policy that covers the Premises, Tenant's fixtures,
       personal property, leasehold improvements or business and which names
       Tenant as a party insured, or additional insured. Landlord hereby waives
       any cause of action it might have against Tenant because of any loss or
       damage arising under Paragraph 10 that is insured against under any
       insurance policy that covers the Building or any property of Landlord
       used in connection with the Building and which names Landlord as a party
       insured, provided that if the cost of restoring the loss or damage
       exceeds the amount of property damage insurance proceeds paid to Landlord
       on account of the loss or damage, Tenant shall remain liable to Landlord
       for the amount of such excess. This provision is cumulative of Paragraph
       15.

              (b) Tenant shall procure and maintain throughout the Lease Term a
       policy or policies of commercial general liability insurance, at its sole
       cost and expense, insuring Tenant and Landlord against

                                       13
<PAGE>   15

       any and all liability for injury to or death of a person or persons,
       occasioned by or arising out of or in connection with the use or
       occupancy of the Premises and the operations and activities of Tenant and
       its employees, agents, contractors and invitees, the limits of such
       policy or policies to be in an amount not less than $2,000,000.00 with
       respect to injuries to or death of any one person and in an amount of not
       less than $2,000,000.00 with respect to any one accident or disaster, and
       shall furnish evidence satisfactory to Landlord of the maintenance of
       such insurance. This insurance coverage shall include blanket contractual
       liability and broad form property damage liability and shall contain an
       exception to any pollution exclusion which insures damage or injury
       arising out of heat, smoke or fumes from a hostile fire. Landlord,
       Landlord's agent, Landlord's mortgagee, and any other parties which
       Landlord shall deem necessary shall be named as an additional insured
       therein as their respective interests may appear. This insurance shall be
       written on an occurrence basis and shall be primary and noncontributory
       to any other insurance carried by Landlord and shall be with companies
       rated A-XV or better in Best's Insurance Guide and authorized to
       transaction business in the State of Washington. Tenant shall obtain a
       written obligation on the part of each insurance company to notify
       Landlord at least ten (10) days prior to cancellation, expiration or
       material alteration of such insurance. It is recommended that Tenant
       carry fire and extended coverage insurance on its personal property, as
       Landlord shall in no event be required to rebuild, repair or replace any
       part of the furniture, equipment, personal property, fixtures and other
       improvements which may have been placed by Tenant on or within the
       Premises.

              (c) Landlord shall maintain throughout the Lease Term, a policy or
       policies of insurance as required pursuant to the terms and conditions of
       Landlord's lender, but in no event less than $50,000,000 coverage on the
       Building.

       31. BINDING EFFECT. The provisions of this Lease shall be binding upon
and inure to the benefit of Landlord and Tenant, respectively, and to their
respective heirs, personal representatives, successors and assigns, subject to
the provisions of Paragraphs 11, 24 and 41 hereof.

       32. NOTICES. Any notice required or permitted to be given hereunder by
one party to the other shall be deemed to be given when deposited in the United
States mail, certified or registered, return receipt requested, with sufficient
postage prepaid, or hand delivered, addressed to the respective party to whom
notice is intended to be given at the address of such party set forth on the
Basic Lease Information. Either party hereto may at any time by giving written
notice to the other party in the aforesaid manner designate any other address,
which, in regard to notices to be given to Tenant, must be within the
continental United States, in substitution of the foregoing address to which any
such notice shall be given. Any notice from Tenant to Landlord regarding a
material default by Landlord hereunder shall also be sent concurrently to
Landlord's lender, at the last address supplied by Landlord or such lender to
Tenant.

       33. BROKERAGE. Tenant warrants that it has not had any dealings with any
broker or agent in connection with the negotiation or execution of this Lease
other than Kidder Mathews & Segner Inc. (Tenant's agent) and Colliers
International, Inc. (Landlord's agent) and Tenant agrees to indemnify Landlord
and hold Landlord harmless from and against any and all cost, expense or
liability for commissions or other compensation or charges claimed by any other
broker or agent with respect to this Lease. Pursuant to the terms of separate
written agreements between Landlord and Colliers International, Inc. and Kidder
Matthews & Segner Inc., Landlord shall be solely responsible for the payment of
all commissions, compensation or charges claimed by each such broker in
connection with the execution of this Lease.

       34. SUBORDINATION. This Lease and all rights of Tenant hereunder are
subject and subordinate to any deed of trust, mortgage or other instrument of
security which does now or may hereafter cover the Building and the Land or any
interest of Landlord therein, and to any and all advances made on the security
thereof, and to any and all increases, renewals, modifications, consolidations,
replacements and extensions of any of such deed of trust, mortgage or instrument
of security. This provision is hereby declared by Landlord and Tenant to be
self-operative and no further instrument shall be required to effect such
subordination of this Lease. Tenant shall, however, upon demand at any time or
times execute, acknowledge and deliver to Landlord any and all instruments and
certificates that, in the judgment of Landlord, may be necessary or proper to
confirm or evidence such subordination, and Tenant hereby irrevocably appoints
Landlord as Tenant's agent and attorney-in-fact for the purpose of executing,
acknowledging and delivering any such instruments and certificates. However,
notwithstanding the generality of the foregoing provisions of this Paragraph 34,
Tenant agrees that any such mortgagee shall have the right at any time to
subordinate any such deed of trust, mortgage or other instrument of security to
this Lease on such terms and subject to such conditions as such mortgagee may
deem appropriate in its discretion. Tenant further covenants and agrees upon
demand by Landlord's mortgagee at any time, before or after the institution of
any proceedings for the foreclosure of any such deed of trust, mortgage or other
instrument of security, or sale of the Building pursuant to any such deed of
trust, mortgage or other instrument of security or voluntary sale, to attorn to
the purchaser upon any such sale and to recognize and attorn to such purchaser
as Landlord under this Lease. The agreement of Tenant to attorn upon demand of
Landlord's mortgagee contained in the immediately preceding sentence shall
survive any such foreclosure sale or trustee's sale. Tenant hereby agrees to
execute, acknowledge and deliver to Landlord's mortgagee any and all instruments
and certificates that Landlord's mortgagee may request in order to confirm or
evidence such attornment. In addition, Tenant acknowledges that following any
foreclosure by Landlord's lender, such lender shall not be: (1) liable for any
previous act or omission of Landlord under this Lease; (2) subject to any
credit, demand, claim, counterclaim, offset or defense which theretofore accrued
to Tenant against Landlord, (3) unless consented to by such lender or permitted
without such lender's consent under the terms of any loan documents, bound by
any previous modification of this Lease, or by any previous prepayment of more
than one month's fixed rent or additional rent; (4) bound by any covenant or
obligation of Landlord to perform, undertake or complete any work in the
Premises or to prepare it for occupancy; (5) required to account for any
security deposit of Tenant other than any security deposit actually delivered to
such lender by Landlord; (6) bound by any obligation to

                                       14
<PAGE>   16

make any payment to Tenant or grant any credits, except for services, repairs,
maintenance and restoration provided for under this Lease to be performed by
Landlord after the date of such attornment; and (7) responsible for any monies
owing by Landlord to Tenant. Notwithstanding anything to the contrary contained
herein, (a) Landlord agrees to use its good faith efforts to obtain a
subordination, non-disturbance and attornment agreement from its existing
mortgagee within 30 days of the execution of this Lease, and (b) the
subordination by Tenant to future mortgagees provided for in this Section 34
shall be subject to the delivery of a non-disturbance agreement in favor of
Tenant on such mortgagee's standard form of subordination, non-disturbance and
attornment agreement.

       35. JOINT AND SEVERAL LIABILITY. If there is more than one Tenant, the
obligations hereunder imposed upon Tenant shall be joint and several. If there
is a guarantor(s) of Tenant's obligations hereunder, the obligations of Tenant
shall be joint and several obligations of Tenant and each such guarantor, and
Landlord need not first proceed against Tenant hereunder before proceeding
against each such guarantor, nor shall any such guarantor be released from its
guarantee for any reason whatsoever, including, without limitation, any
amendment of this Lease, any assignment of this Lease or sublease of all or any
part of the Premises, any forbearance by Landlord or waiver of any of Landlord's
rights, the failure to give Tenant or any such guarantor any notices, or the
release of any party liable for the payment or performance of any of Tenant's
obligations hereunder.

       36. BUILDING NAME AND ADDRESS. Landlord reserves the right at any time to
change the name by which the Building is designated and its address, and
Landlord shall have no obligation or liability whatsoever for costs or expenses
incurred by Tenant as a result of such name change or address change of the
Building.

       37. ESTOPPEL CERTIFICATES; FINANCIAL STATEMENTS.

              (a) Tenant agrees to furnish from time to time, within ten (10)
       business days following the request by Landlord or any successor to
       Landlord or by the holder of any deed of trust or mortgage covering the
       Land and Building or any interest of Landlord therein, an estoppel
       certificate signed by Tenant to the effect that this Lease is then
       presently in full force and effect and specifying any modifications; that
       the Lease Term has commenced and the full rental is then accruing
       hereunder; that Tenant has accepted possession of the Premises and that
       any improvements required by the terms of this Lease to be made by
       Landlord have been completed to the satisfaction of Tenant; that no rent
       under this Lease has been paid more than thirty (30) days in advance of
       its due date; that the address for notices to be sent to Tenant is as set
       forth in this Lease; that Tenant, as of the date of such certificate, has
       no charge, lien or claim of offset under this Lease or otherwise against
       rents or other charges due or to become due hereunder; and that to the
       knowledge of Tenant, Landlord is not then in default under this Lease. To
       the extent that Tenant believes any of the foregoing to be inaccurate,
       Tenant shall specifically enumerate in the certificate the alleged
       inaccuracy and Tenant's basis for refusing to certify to such facts. At
       Landlord's option, any such certificate may also contain an
       acknowledgment by Tenant of receipt of notice of the assignment of this
       Lease to such holder and the agreement by Tenant with such holder that
       from and after the date of such certificate, Tenant will not pay any rent
       under this Lease more than thirty (30) days in advance of its due date,
       will not surrender or consent to the modification of any of the terms of
       this Lease nor to the termination of this Lease by Landlord, and will not
       seek to terminate this Lease by reason of any act or omission of Landlord
       until Tenant shall have given written notice of such act or omission to
       the holder of such deed of trust or mortgage (at such holder's last
       address furnished to Tenant) and until a reasonable period of time shall
       have elapsed following the giving of such notice, during which period
       such holder shall have the right, but shall not be obligated, to remedy
       such act or omission; provided, however, that (i) the agreement of Tenant
       described in this sentence will be of no effect under such certificate
       unless Tenant is furnished by such holder with a copy of any assignment
       to such holder of Landlord's interest in this Lease within ninety (90)
       days after the date of such certificate, and (ii) the agreement of Tenant
       with such holder that is embodied in such certificate shall terminate
       upon the subsequent termination of any such assignment. In the event
       Tenant shall fail or neglect to execute, acknowledge and deliver any such
       certificate, Landlord may, as the agent and attorney-in-fact of Tenant,
       execute, acknowledge and deliver the same, and Tenant hereby irrevocably
       nominates, constitutes and appoints Landlord as Tenant's proper and legal
       agent and attorney-in-fact for such purpose. Such power of attorney shall
       not terminate on disability of the principal.

              (b) Tenant shall also furnish to Landlord within fifteen (15) days
       following a written request by Landlord, but no more often than one time
       per calendar year, a statement of the financial condition of Tenant
       prepared by an independent certified public accountant in a form
       reasonably satisfactory to Landlord.

       38. MECHANIC'S LIENS. Nothing contained in this Lease shall authorize
Tenant to do any act which shall in any way encumber the title of Landlord in
and to the Premises or the Building or any part thereof; and if any mechanic's
or materialman's lien is filed or claimed against the Premises or Building or
any part thereof in connection with any work performed, materials furnished or
obligation incurred by or at the request of Tenant, Tenant will promptly pay
same or cause it to be released of record. If the lien is not released of record
within, or default in payment thereof shall continue for, twenty (20) days after
written notice thereof from Landlord to Tenant, without limiting or otherwise
affecting any of Landlord's other rights or remedies and without waiving any
event of default by Tenant, Landlord shall have the right and privilege at
Landlord's option of paying the same or any portion thereof without inquiry as
to the validity thereof, and any amounts so paid, including expenses and
interest, shall be so much additional rent hereunder from Tenant to Landlord and
shall be repaid to Landlord immediately on demand therefor. Notwithstanding the
foregoing, Tenant shall have the right, after written notice to Landlord, to
contest in good faith and with all due diligence any mechanic's lien and shall
not be required to pay any claim secured by such mechanic's lien provided that
such lien would not be satisfied out of the interest of Landlord in the Premises
or the Building by reason of such delay, and further provided that Tenant will
at Tenant's expense, defend Landlord and

                                       15
<PAGE>   17

pay all costs reasonably incurred by Landlord relating to the contest in the
event Landlord is joined in any suit pertaining thereto or in the event any lien
affidavit is filed claiming a lien upon Landlord's interest in the Premises or
in the Building. The foregoing sentence shall not imply any right on the part of
Tenant to affect Landlord's interest in the Premises or the Building.

       39. TAXES AND TENANT'S PROPERTY. Tenant shall be liable for all taxes
levied or assessed against personal property, furniture or fixtures placed by
Tenant in the Premises. If any such taxes for which Tenant is liable are levied
or assessed against Landlord or Landlord's property and if Landlord elects to
pay the same or if the assessed value of Landlord's property is increased by
inclusion of personal property, furniture or fixtures placed by Tenant in the
Premises, and Landlord elects to pay the taxes based on such increase, Tenant
shall pay Landlord upon demand that part of such taxes for which Tenant is
primarily liable hereunder.

       40. CONSTRUCTIVE EVICTION. Tenant shall not be entitled to claim a
constructive eviction from the Premises unless Tenant shall have first notified
Landlord in writing of the condition or conditions giving rise thereto, and, if
the complaints be justified, unless Landlord shall have failed to remedy such
conditions within thirty (30) days after receipt of said notice, provided, that
if such default cannot be cured within such 30-day period and Landlord is
diligently pursuing to cure same, Landlord shall be afforded additional time in
order to cure or remedy such default.

       41. LANDLORD'S LIABILITY. The liability of Landlord to Tenant for any
default by Landlord under the terms of this Lease shall be limited to Tenant's
actual direct, but not consequential, damages therefor and shall be recoverable
only from the interest of Landlord in the Building and the Land, and Landlord
shall not be personally liable for any deficiency except that Landlord shall at
all times have personal liability to Tenant for repayment of the Security
Deposit in the event of foreclosure as provided in Section 34 hereof. This
clause shall not be deemed to limit or deny any remedies which Tenant may have
in the event of default by Landlord hereunder which do not involve the personal
liability of Landlord. Notwithstanding anything to the contrary contained in
this Lease, in the event Landlord sells, assigns, transfers or conveys its
interest in the Building and the Land, Landlord shall have no liability for any
acts or omissions that occur after the date of said sale, assignment, transfer
or conveyance.

       42. EXECUTION BY LANDLORD. The submission of this Lease to Tenant shall
not be construed as an offer, and Tenant shall not have any rights with respect
hereto unless and until Landlord shall, or shall cause its managing agent to,
execute a copy of this Lease already executed and delivered by Tenant to
Landlord, and deliver the same to Tenant.

       43. NO WAIVER. No waiver by Landlord of any of its rights or remedies
hereunder, or otherwise, shall be considered a waiver of any other or subsequent
right or remedy of Landlord; no delay or omission in the exercise or enforcement
by Landlord of any rights or remedies shall ever by construed as a waiver of any
right or remedy of Landlord; and no exercise or enforcement of any such rights
or remedies shall ever be held to exhaust any right or remedy of Landlord.

       44. NO THIRD PARTY BENEFICIARY. This Lease is for the sole benefit of
Landlord, its successors and assigns, and Tenant, its permitted successors and
assigns, and it is not for the benefit of any third party.

       45. NUMBER AND GENDER. Words of any gender used in this Lease shall be
held and construed to include any other gender, and words in the singular number
shall be held to include the plural, unless the context otherwise requires.

       46. FORCE MAJEURE. Whenever a period of time is herein prescribed for
action to be taken by Landlord or Tenant, neither Landlord nor Tenant, as the
case may be, shall be liable or responsible for, and there shall be excluded
from the computation for any such period of time, any delays due to strikes,
riots, acts of God, shortages and/or unavailability of labor or materials, war,
governmental laws, regulations or restrictions, or any other cause of any kind
whatsoever which are beyond the reasonable control of either Landlord or Tenant;
provided that the affected party provides prompt written notice of the
circumstances to the other party and uses its commercially reasonable efforts to
mitigate the consequences. If this Lease specifies a time period for performance
of an obligation, that time period shall be extended by the period of any delay
in performance caused by any of the events of force majeure described herein.
Notwithstanding the foregoing, force majeure shall not excuse Tenant from its
obligation to timely pay rent.

       47. HAZARDOUS AND TOXIC MATERIALS.

       (a) For purposes of this Lease, hazardous or toxic materials shall mean
asbestos containing materials and all other materials, substances, wastes and
chemicals classified as hazardous or toxic substances, materials, wastes or
chemicals or otherwise regulated under then-current applicable federal, state or
local governmental laws, rules or regulations.

       (b) Tenant shall not knowingly incorporate into, or generate, store, use
or otherwise place or dispose of at, or transport to or from, the Premises, the
Building or on the Land any hazardous or toxic materials, except in the ordinary
course of Tenant's business and then only if (i) such materials are handled and
disposed of in accordance with industry standards for safety, storage, use and
disposal, (ii) Tenant provides to Landlord an annual summary of permits that
Tenant has or has applied for from local, state and federal agencies regarding
Tenant's activities at the Building in connection with hazardous or toxic
materials together with a copy of Tenant's most current environmental health and
safety plan which contains Tenant's storage and disposal protocol(s) (herein
referred to collectively as "TENANT'S EH&S PLAN"), and (iii) such materials are
used, transported, stored, handled and disposed of in accordance with all
applicable governmental laws, rules and regulations. Landlord shall have the

                                       16
<PAGE>   18

right, but not the obligation, to periodically inspect and otherwise investigate
the Premises for the presence of hazardous or toxic materials.

       (c) Landlord shall, at its sole cost and expense, investigate, remove and
remediate pursuant to and in compliance with all applicable governmental
standards, laws, rules and regulations, any hazardous or toxic materials whose
presence at the Premises, Building or Land arises from the act or omission of
Landlord. Landlord shall defend and indemnify Tenant and save it harmless from
all suits, actions, damages, liability and expense arising from any release of
hazardous or toxic materials to or from the Premises, Building or Land that
either (i) occurred or existed prior to the Lease Term or (ii) arises from an
act or omission of Landlord or its invitees (excluding tenants at the Building).
Landlord shall not dispose of or release at the Premises, Building or the Land
any hazardous or toxic materials in violation of applicable law and shall remove
or remediate all hazardous or toxic materials disposed of or released by
Landlord or its invitees (excluding tenants at the Building) at the Premises,
Building or Land of which Landlord becomes aware when and if required by
applicable law and in a manner that will not materially and adversely affect
Tenant's access, use or occupancy of the Premises.

       (d) If Tenant or Landlord ever has any knowledge of the presence in the
Premises or the Building or the Land of hazardous or toxic materials which
affect the Premises, Tenant shall notify Landlord and vice versa in writing
promptly after obtaining such knowledge. Tenant acknowledges that Landlord has
advised Tenant of the existence of asbestos containing materials used during the
initial construction of the Building. An operation and maintenance plan has been
established to monitor such materials and has been made available to Tenant;
however, Landlord has been advised that such materials do not pose a health
hazard. Landlord represents and warrants, as of the date hereof and to the best
of its knowledge, that there are no hazardous materials or environmental
conditions at the Building that could adversely affect Tenant or its Sole
Permitted Use. Tenant acknowledges that Landlord has provided copies of its
latest environmental reports for Tenant's review.

       (e) If Tenant or its employees, agents or contractors shall ever violate
the provisions of Paragraph (b) of this subsection or otherwise contaminate the
Premises or the Building or Land, then Tenant shall, at its sole cost and
expense, clean up, remove and dispose of the material causing the violation, or
remove or remediate the contamination pursuant to and in compliance with all
applicable governmental standards, laws, rules and regulations and shall repair
any damage to the Premises or Building arising from the violation or
contamination within such period of time as may be reasonable under the
circumstances after written notice by Landlord (collectively, "TENANT'S
ENVIRONMENTAL CORRECTIVE WORK"). Tenant shall notify Landlord of its method,
time and procedure for any clean up or removal and Landlord shall have the right
to require reasonable changes in such method, time or procedure or to require
the same to be done after normal business hours to the extent reasonably
feasible. Tenant's obligations under this subsection shall survive the
termination or expiration of this Lease.

       (f) If any Tenant's Environmental Corrective Work (i) is to occur outside
of the Premises or (ii) will in any way affect any portion of the Building other
than the Premises, then Landlord shall have the right, but not the obligation,
after giving Tenant advance notice and an opportunity to perform such Work, to
undertake Tenant's Environmental Corrective Work, and Tenant shall reimburse
Landlord for reasonable expenses incurred by Landlord in undertaking Tenant's
Environmental Corrective Work. Tenant shall allow Landlord, its agents,
employees and contractors such access to the Premises as Landlord may reasonably
request in order to perform such Tenant's Environmental Corrective Work. In
addition, Tenant shall protect, indemnify, defend and hold harmless Landlord and
its directors, partners, officers, employees, agents, parents, subsidiaries,
successors and assigns from any loss, damage cost, fine, penalty, expense or
liability (including reasonable attorneys' fees and costs) directly or
indirectly arising out of or attributable to the use, generation, manufacture,
production, storage, release, discharge, disposal or presence of a hazardous or
toxic material on the Premises, Building or Land caused by Tenant and its
employees, agents, contractors, licensees or invitees, or a breach of any
representation, warranty, covenant or agreement contained in this Paragraph 47,
including, without limitation, the costs of any required or necessary repairs,
cleanup or detoxification of the Premises, Building or Land and the preparation
and implementation of any closure, remedial or other required plans and any
natural resources damage. Tenant's obligations under this subsection shall
survive the termination or expiration of this Lease.

       (g) Landlord acknowledges that Tenant uses hazardous and toxic materials
in its business. Prior to the execution of this Lease, Tenant has provided a
comprehensive list of all chemicals and hazardous materials used in Tenant's
business. In addition, prior to bringing any hazardous or toxic materials into
the Building or onto the Land, Tenant shall provide to Landlord a copy of
Tenant's EH&S Plan, which shall be in compliance with applicable laws, for such
hazardous or toxic materials. Tenant agrees to comply with Tenant's EH&S Plan
and may utilize other hazardous or toxic materials which were not previously
approved by Landlord, without Landlord's prior written consent, provided such
usage complies with all of the applicable provisions of this Lease. Tenant
hereby agrees to be responsible for the cost of any increased insurance
resulting solely from Tenant's use of such hazardous materials. Landlord shall
have the right to conduct an environmental audit of the Premises, at Landlord's
sole expense, no more than one (1) time per year.

       48. TELECOMMUNICATIONS. Tenant and its telecommunications companies,
including but not limited to local exchange telecommunications companies and
alternative access vendor services companies, shall have no right of access to
and within the Building, for the installation and operation of
telecommunications systems including but not limited to voice, video, data, and
any other telecommunications services provided over wire, fiber optic,
microwave, wireless, and any other transmission systems, for part or all of
Tenant's telecommunications within the Building and from the Building to any
other location without Landlord's prior written consent, which consent shall not
be unreasonably, withheld or delayed provided such provider executes Landlord's
standard form of Telecommunications License Agreement. Tenant expressly
understands and agrees that Landlord reserves the right to grant or deny access
(to the Building or any portion thereof, including, without limitation, the
Premises) to any telecommunications service provider whatsoever, and that Tenant
shall have no right to demand or attempt to

                                       17
<PAGE>   19

require Landlord to grant any access to any such telecommunications service
provider. Moreover, Tenant acknowledges and agrees that, in the event any such
telecommunications service provider desires access to the Building to serve any
or all tenants thereof, such access shall be prescribed and governed by the
terms and provisions of Landlord's standard Telecommunications License
Agreement, which must be executed and delivered to Landlord by such
telecommunications service provider before it is allowed any access whatsoever
to the Building. Subject to the requirements provided herein, Landlord
acknowledges that Tenant will select its own telecommunications provider who,
subject to the execution of Landlord's standard Telecommunications License
Agreement, shall have access to the Building and its transmission systems to
accomplish the purposes hereof.

       49. LANDLORD'S FEES. Whenever Tenant requests Landlord to take any action
or give any consent required or permitted under this Lease, Tenant will
reimburse Landlord for Landlord's reasonable costs incurred in reviewing the
proposed action or consent, including without limitation reasonable attorneys',
engineers' or architects' fees, within ten (10) days after Landlord's delivery
to Tenant of a statement of such costs. Tenant will be obligated to make such
reimbursement without regard to whether Landlord consents to any such proposed
action.

       50. NO LIGHT, AIR OR VIEW EASEMENT. Any diminution or shutting off of
light, air or view by any structure which may be erected on the Land or lands
adjacent to the Building shall in no way affect this Lease or impose any
liability on Landlord (even if Landlord is the adjacent land owner).

       51. APPLICABLE LAW; CONSENT TO JURISDICTION. THIS LEASE SHALL BE GOVERNED
BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF WASHINGTON AND THE
LAWS OF THE UNITED STATES APPLICABLE TO TRANSACTIONS IN THE STATE OF WASHINGTON.
TENANT HEREBY IRREVOCABLY AGREES THAT ANY LEGAL ACTION OR PROCEEDING AGAINST IT
WITH RESPECT TO THIS LEASE MAY BE MAINTAINED IN THE COURTS OF SNOHOMISH COUNTY,
WASHINGTON OR IN THE U.S. DISTRICT COURT FOR THE WESTERN DISTRICT OF WASHINGTON,
AND TENANT HEREBY CONSENTS TO THE JURISDICTION AND VENUE OF SUCH COURTS.

       52. WAIVER OF JURY TRIAL. TO THE MAXIMUM EXTENT PERMITTED BY LAW,
LANDLORD AND TENANT EACH WAIVE RIGHT TO TRIAL BY JURY IN ANY LITIGATION ARISING
OUT OF OR WITH RESPECT TO THIS LEASE.

       53. CONFIDENTIALITY. Tenant acknowledges that the terms and conditions of
this Lease are to remain confidential for Landlord's benefit, and may not be
disclosed by Tenant to anyone, by any manner or means, directly or indirectly,
without Landlord's prior written consent. Notwithstanding anything contained
herein to the contrary, Landlord acknowledges and consents to Tenant's
obligation to make such disclosures pertaining to this Lease that it shall deem
necessary to comply with all securities laws and any other laws, statutes,
rules, regulations or order of a court of law. The consent by Landlord to any
disclosures shall not be deemed to be a waiver on the part of Landlord of any
prohibition against any future disclosure.

       54. BACK-UP GENERATOR. Landlord agrees to provide a location that Tenant
may use, on a non-exclusive basis, to install an emergency generator and fuel
system at Tenant's sole cost and expense. Such generator and area will be
designated by Landlord (in an area reasonably acceptable to Tenant) and, to the
extent permitted by applicable ordinance, located adjacent to the Building and
shall be subject to Landlord's review and approval of the configuration,
placement and type of equipment that will be installed by Tenant, such approval
not to be unreasonably withheld, conditioned or delayed. Once the location for
the generator has been established, Tenant shall provide screening or other
reasonable means to secure the generator. The space provided for the generator
shall not be included in the calculation of Rentable Space of the Premises.
Tenant shall be responsible for and shall pay all costs and expenses of
providing, installing, maintaining, operating, testing, repairing and, upon
termination of this Lease, removing such back-up generator and fuel system.
Tenant shall pay directly to its supplier for all fuel consumed by the back-up
generator and Tenant shall comply with all federal, state and local laws, rules
and ordinances and the operative office association, together with the
provisions of this Lease, concerning the installation, use storage and disposal
of diesel fuel and storage tanks. Provided, further, that Tenant shall procure
and maintain throughout the term of this Lease, all permits, licenses,
registrations, financial assurances necessary for the installation, construction
and operation of the back-up generator and fuel tanks.

       55. SIGNAGE. Tenant shall be allowed to utilize a portion of Landlord's
exterior monument signage equal to at lest 25% of the overall signage. In
addition, Tenant shall be entitled to Building standard lobby signage equal to
at least 25% of the overall signage. Notwithstanding the foregoing, Tenant shall
be responsible for the cost of installing and maintaining such signage and the
location, type and size of such signage shall be reasonably acceptable to
Landlord. In addition, all signage must conform to all governmental codes and
ordinances. Landlord represents and Tenant understands that there will be no
signage of any kind permitted on the Building exterior except the Building
address and signage regarding Landlord's ownership of the Building which shall
only be displayed on the Building's entry doors.

       56. SPECIAL TENANT INSTALLATIONS. Landlord acknowledges that Tenant
desires certain special installations in the Premises and certain Service Areas
more particularly described hereinbelow. Subject to Landlord's review and
approval of the Approved Working Drawings which shall be delivered in accordance
with the terms of Exhibit D hereto and which in all cases shall specifically
address such desired special installations, such Landlord consent not to be
unreasonably withheld, conditioned or delayed, Tenant shall be permitted to
complete the following: (a) installation, maintenance, operation, modification
and removal of an HVAC system on the Building's roof related to Tenant's clean
room facilities; (b) locate lab hoods and antennae on the Building's roof (such
rooftop equipment to be governed by Landlord's standard rider related to rooftop
equipment); (c) installation, maintenance, operation, modification and removal
of an emergency generator and fuel system as more particularly

                                       18
<PAGE>   20

described herein; (d) construct an internal stairwell between its floors
(provided, further, that said stairwell shall not impact the overall square
footage of the Premises); and (e) obtain access from time to time, with a
representative of Landlord present, to the areas above the acoustical ceiling to
install, maintain and inspect special tenant installations to the Premises. In
connection with all such special tenant installations, Landlord shall have the
option of requiring Tenant to remove same, at Tenant's cost, following the
expiration of the Lease Term. In addition, Tenant acknowledges that Landlord
shall not be unreasonable in its denial of any such special installation in the
event (i) Landlord's third-party engineering consultant determines that such
tenant installation will subject the Building or its occupants to unnecessary
structural or safety risks or potential harm (e.g., an assessment of the
structural integrity resulting from the desired internal stairwell), or (ii)
violates local ordinance, or (iii) impairs the rights of other existing or
prospective tenants of the Building.

       57. CATEGORY 5 CABLING. Landlord agrees to keep the existing Category 5
cabling system located on the 2nd and 3rd floors of the Building in place during
the Lease Term and to permit Tenant to utilize such existing Category 5 cabling
system on those floors so long as, in the reasonable judgment of Landlord, that
it does not adversely impact Landlord's plans for the Building.

       58. MISCELLANEOUS. Notwithstanding anything to the contrary in this
Lease, (a) if another tenant of the Building is violating the terms of its lease
and such violation is harming Tenant, Landlord agrees to take commercially
reasonable action to enforce its rights under said other lease so as to
eliminate or mitigate the harm caused by such tenant to Tenant; and (b) the
liability of either party under the terms of this Lease shall be limited to the
other party's actual, direct, but not consequential damages, including, without
limitation, damages for loss or profits or special or punitive damages.

       IN WITNESS WHEREOF, this Lease Agreement is entered into by the parties
hereto on the day and year first set forth above.

LANDLORD:                                    TENANT:
--------                                     ------

WIREDZONE PROPERTY, L.P.                     COMBIMATRIX CORPORATION

By:     WiredZone Property GenPar, LLC,
        its general partner                  By: /s/ Patrick de Maynadier
                                                --------------------------------
                                             Its:    Executive Vice President
                                                     and General Counsel
        By: /s/ Judson Pankey                   --------------------------------
           ----------------------------
        Its:
            ---------------------------

                                       19
<PAGE>   21

STATE OF TEXAS               SECTIONS
                             SECTIONS
COUNTY OF DALLAS             SECTIONS

       I certify that I know or have satisfactory evidence that
_______________________ is the person who appeared before me, and said person
acknowledged that he/she signed this instrument, on oath stated that he/she was
authorized to execute this instrument and acknowledged it as the
_________________ of WiredZone Property GenPar, LLC, general partner of
WIREDZONE PROPERTY, L.P., to be the free and voluntary act of such party for the
uses and purposes mentioned in this instrument.

       DATED: October __, 2000.

                                    --------------------------------------------
                                    Print Name:
                                               ---------------------------------
                                    NOTARY PUBLIC in and for the State of Texas,
                                    residing at
                                               ---------------------------------
                                    My Appointment expires:
                                                           ---------------------

(use this space for notarial stamp/seal)

STATE OF WASHINGTON          SECTIONS
                             SECTIONS
COUNTY OF _____________      SECTIONS

       I certify that I know or have satisfactory evidence that
_______________________ is the person who appeared before me, and said person
acknowledged that he/she signed this instrument, on oath stated that he/she was
authorized to execute this instrument and acknowledged it as the
_________________ of COMBIMATRIX CORPORATION, a Delaware corporation, to be the
free and voluntary act of such party for the uses and purposes mentioned in this
instrument.

        DATED: October __, 2000.

                                      ------------------------------------------
                                      Print Name:
                                                 -------------------------------
                                                                    NOTARY

                                      PUBLIC in and for the State of Washington,
                                      residing at
                                                 -------------------------------
                                      My Appointment expires:
                                                             -------------------

(use this space for notarial stamp/seal)

                                       20
<PAGE>   22

                         EXHIBIT "A" TO LEASE AGREEMENT

                          LEGAL DESCRIPTION OF THE LAND

       Tracts 3 and 4 of Snohomish County Binding Site Plan recorded under
Recording No. 8311075005. Situated in the County of Snohomish, State of
Washington.

                           EXHIBIT "A" - PAGE 1 OF 1
<PAGE>   23

                         EXHIBIT "B" TO LEASE AGREEMENT

                             FLOOR PLAN OF PREMISES

                                [To Be Provided]

                           EXHIBIT "B" - PAGE 1 OF 1
<PAGE>   24

                         EXHIBIT "C" TO LEASE AGREEMENT

                                    HOLIDAYS

        January 1st                                 New Years Day

        Last Monday in May                          Memorial Day

        July 4th*                                   Independence Day

        First Monday in September                   Labor Day

        Fourth Thursday in November                 Thanksgiving Holidays
          plus Friday following

        December 25th                               Christmas Day

*or date legally celebrated

                         EXHIBIT "D" TO LEASE AGREEMENT

                        LEASEHOLD IMPROVEMENTS AGREEMENT

       THIS LEASEHOLD IMPROVEMENTS AGREEMENT (this "AGREEMENT") is made and
entered into this ____ day of October, 2000, in connection with that certain
Lease Agreement (the "LEASE"), executed concurrently herewith by and between
WIREDZONE PROPERTY, L.P. ("LANDLORD") and COMBIMATRIX CORPORATION ("TENANT"),
and constitutes the entire agreement of Landlord and Tenant with respect to the
construction and completion of the Premises described in the Lease. In the event
of a conflict between the provisions of this Agreement and other provisions of
the Lease, the provisions of this Agreement will control. Terms defined in the
Lease, when used herein, shall have the same meanings as are ascribed to them in
the Lease.

       1. Since the Premises have been occupied by a previous tenant, Tenant
hereby agrees to accept the Premises in its "as is" condition; provided,
however, the Premises shall be in broom-clean condition and all Building systems
(including, without limitation, the structural roof, roof membrane, walls,
foundations, existing HVAC and utility systems) shall be in good working order
prior to the delivery of the Premises to Tenant. Landlord agrees, at Landlord's
expense, to upgrade the Building common lobby and central elevator lobby,
central elevator lobby cabs and security area to "WiredZone" specifications at
Landlord's sole cost and expense within 180 days following applicable city
approval/permits related to such work, which city approval and permitting shall
be diligently sought within 60 days of the Commencement Date of the Lease.

       2. Initially, Tenant shall provide to Landlord for its reasonable
approval space plans for the Premises prior to commencing working drawings.
Following Landlord's written approval of such space plans (with a response to be
provided within five (5) business days following receipt thereof), Tenant shall
provide to Landlord for its reasonable approval final working drawings, prepared
by Tenant's Architect/Engineer, of all improvements that Tenant proposes to
install in the Premises; such working drawings shall include the partition
layout, internal stairwell, ceiling plan, electrical outlets and switches,
telephone outlets, built-in kitchen equipment, drawings for any modifications to
the mechanical and plumbing systems of the Building, and detailed plans and
specifications for the construction of the improvements called for in the Lease
(including, without limitation, those detailed in Paragraph 56 of the Lease) and
under this Exhibit in accordance with all applicable governmental laws, codes,
rules, and regulations. Such plans will also address the installation of
Tenant's switching equipment. If Tenant's proposed construction work will affect
the Building's HVAC, electrical, mechanical, and plumbing systems, the working
drawings pertaining thereto shall be prepared by Tenant's engineer with Landlord
approval. Such working drawings and the improvements depicted thereon shall (a)
comply with all applicable governmental laws, codes, rules, and regulations, (b)
be sufficiently detailed to allow construction of the improvements in a good and
workmanlike manner, and (c) conform to the reasonable rules and regulations
promulgated from time to time by the Landlord for the construction of tenant
improvements. As used herein, "Approved Working Drawings" shall mean the final
working drawings reasonably approved by Landlord, as amended from time to time
by any approved changes thereto, and "Work" shall mean all improvements to be
constructed in accordance with and as indicated on the Approved Working
Drawings. The Approved Working Drawings shall be generated from and based upon
Tenant's architect's initial programming for the Premises, which Landlord has
reviewed and provided conceptual approval. Landlord acknowledges that the Work
will be performed in several phases during the Lease Term, each of which shall
collectively constitute the "Work" for purposes hereof. Landlord's approval of
the Working Drawings shall not be a representation or warranty by Landlord that
such drawings are adequate for any use, purpose, or condition, or that such
drawings comply with any applicable law or code, but shall merely be the consent
of Landlord to the performance of the Work. All changes in the Work for
partition changes or other material or structural changes must receive the prior
written approval of Landlord which approval shall not be unreasonably withheld,
delayed or conditioned, and in the event of any such approved change Tenant
shall, upon completion of the Work, furnish Landlord with an accurate,
reproducible "marked-up" plan (e.g., sepia) of the improvements as constructed,
which plan shall be incorporated into this Lease by this reference for all
purposes, as well as copies of all specifications and warranties on equipment
installed and connected to the Building's systems.

                           EXHIBIT "C" - PAGE 1 OF 1
<PAGE>   25

       3. The Work shall be performed only by contractors and subcontractors
approved in writing by Landlord, in Landlord's reasonable discretion, such
consent not to be unreasonably withheld, conditioned or delayed. Tenant's
construction manager shall also be subject to the review and approval of
Landlord, such consent not to be unreasonably withheld or delayed based upon
Landlord's review of the qualifications and creditworthiness of such proposed
construction manager candidates. Tenant hereby advises Landlord that it is
submitting these candidates to be considered for the position of construction
manager for the tenant improvements to the Premises: DPR Contractors, Rafn
Contractors and Howard S. Wright Contractors. Landlord reserves the right to
provide other suggested contractors to Tenant for Tenant to review and consider.
All contractors and subcontractors shall be required to procure and maintain
insurance against such risks, in such amounts, and with such companies as
Landlord may reasonably require. Certificates of such insurance, must be
received by Landlord before the Work is commenced. The Work shall be performed
in a good and workmanlike manner that is free of defects and is in conformance
with the Approved Working Drawings, and shall be performed in such a manner and
at such times as to maintain harmonious labor relations and not to interfere
with or delay Landlord's other contractors, the operation of the Building, and
the occupancy thereof by other tenants. All contractors and subcontractors shall
contact Landlord and schedule reasonable time periods during which they may use
Building facilities in connection with the Work (e.g., elevators, excess
electricity, etc.). Landlord agrees to cooperate with Tenant in order to
expedite the completion of the Work.

       4. Tenant shall bear the entire cost of performing the Work (including,
without limitation, design of the Work and preparation of the Working Drawings,
costs of construction labor and materials, additional janitorial services and
trash removal to the extent the contractor fails to provide such services,
related taxes and insurance costs, all of which costs are herein collectively
called the "Total Construction Costs"), subject to the reimbursement from the
Tenant Improvement Allowance (as herein defined).

       5. In the event Tenant desires any changes to the Approved Working
Drawings, Tenant shall submit the proposed change order to Landlord in writing
for Landlord's approval, such approval not to be unreasonably withheld,
conditioned or delayed. Landlord shall advise Tenant of such approval or
disapproval within five (5) business days following receipt by Landlord of such
request, which approval shall not be unreasonably withheld, conditioned or
delayed. If Landlord fails to approve or disapprove the Change Order within five
(5) business days following delivery of the Change Order by Tenant to Landlord,
Landlord shall be deemed to have approved the proposed change and it may be
implemented by Tenant.

       6. The Lease Term and Tenant's rental obligations under the Lease will
commence upon the Commencement Date set forth in the Lease, and Tenant shall
cause certain identified portions of the Work to be completed in accordance with
the build-out schedule for the Premises set forth in Rider No. 106 to the Lease.
Tenant agrees that upon substantial completion of the Work and each phase
thereof, Tenant will occupy and accept the Premises. Except as otherwise
provided in this Lease, Tenant shall not enter into possession of the Premises
prior to substantial completion for purposes other than construction and/or
preparing the Premises for move-in (which entry shall be at Tenant's sole risk
since Tenant is causing the construction of the Premises) without Landlord's
written consent, which consent shall not be unreasonably withheld, conditioned
or delayed, other than in such event, Tenant acknowledges that its indemnity
contained in the Lease shall be applicable to such period of early possession.

       7. Landlord shall provide a construction allowance (the "ALLOWANCE") of
$10.00 per square foot of Rentable Space in the Premises. Such funds shall be
paid to Tenant within 30 days following the completion of the Work (or
applicable stages thereof) and Landlord's receipt of the following: (i)
submission of an AIA draw request, (ii) a certification from Landlord's and
Tenant's construction managers that such work was completed in a good and
workmanlike manner, (iii) copies of executed lien waivers and invoices, and (iv)
a certificate of occupancy from the appropriate governmental authority as well
as copies of any licenses required for Tenant's use and occupancy of the
Premises and any auxiliary equipment installed by Tenant (but in no event
earlier than Tenant's occupancy of the Premises and the payment of the first
month of Base Rental). The Allowance may be used by Tenant for any construction
obligations of Tenant (but not for the payment of Base Rental and such shall not
be applied to any obligations of Landlord under Paragraph 47 of the Lease). Any
unused portion of the Allowance shall not be available for subsequent
construction or alterations by Tenant. In the event the Work is completed in
identified stages, Landlord agrees to make available the applicable portion of
the Allowance (i.e., the allocable portion of the Allowance in connection with
the square footage of the area being constructed for Tenant's use and occupancy
and for which Base Rental will thereafter be paid upon), provided that Landlord
receives documentation evidencing the completion of such portion of the Work as
well as lien waivers from the applicable contractors and subcontractors in
connection with such portion of the Work. With regard to disbursement, Landlord
agrees, with regard to each identified stage of the Work, to make the applicable
portion of the Allowance available as follows: the first third shall be made
available to Tenant at the commencement of such phase or stage of Work; the
second third shall be made available to Tenant when two-thirds of such phase or
stage of Work is completed as verified by Landlord's inspectors; and the final
third shall be made available to Tenant when such phase or stage of Work is
completed, as verified by Landlord's inspectors, and the materials described in
clauses (ii) through (iv) above which relate to such portion of the Work have
been delivered.

       8. Tenant, through its Landlord-approved agent, shall supervise the Work.
Landlord or its construction manager shall coordinate with Tenant, Tenant's
construction manager and its contractor with respect to the relationship between
the Work (including, but not limited to scheduling of Work, Building policies
and procedures and inspection of the Work), the Building, and the Building's
systems. Tenant shall be obligated to pay a construction supervision fee of five
percent (5%) of the Total Construction Costs to Landlord or Landlord's
construction manager, such fee not to exceed $75,000. Tenant hereby covenants to
comply with Landlord's guidelines regarding construction policies and procedures
and further agrees to cause all contractors and

                           EXHIBIT "D" - PAGE 2 OF 3
<PAGE>   26

subcontractors to abide by such policies and procedures. Landlord shall, prior
to commencement of construction hereunder, provide Tenant's contractors with a
staging area not to exceed 1,000 square feet which shall be reasonably located
and adequate for performing the Work. Landlord may, from time to time, relocate
the staging area if it interferes with Landlord's or another tenant's usage of
the Building. In addition to the indemnification for mechanic's liens set forth
in this Lease, Tenant hereby indemnifies Landlord and its property manager from
any and all claims, damages, liabilities and causes of action arising from the
construction of the tenant improvements to the Premises except to the extent
caused by the gross negligence or intentional misconduct of Landlord. Tenant
understands that Landlord will require weekly construction meetings.

       9. All sums payable by Tenant to Landlord under this Agreement shall
constitute additional rental under the Lease. In the event Tenant shall fail to
pay any amount of such additional rental when due, and any such failure
continues for a period of ten (10) days after written notice of such failure is
issued by Landlord to Tenant, then such failure shall constitute an Event of
Default under the Lease and hereunder and Landlord shall have the right to
exercise all of its rights and remedies under the Lease and under applicable
law. In no event shall any termination of the Lease by Landlord relieve Tenant
of Tenant's obligation to pay to Landlord the sums payable by Tenant hereunder.

                           EXHIBIT "D" - PAGE 3 OF 3
<PAGE>   27

       EXECUTED as of the day and year first above written.

                                   LANDLORD:

                                   WIREDZONE PROPERTY, L.P.

                                   By:  WiredZone Property GenPar, LLC,
                                        its general partner

                                        By:
                                             -----------------------------------
                                        Its:
                                             -----------------------------------

                                   TENANT:

                                   COMBIMATRIX CORPORATION

                                   By:
                                      ------------------------------------------
                                   Title:
                                         ---------------------------------------

                           EXHIBIT "D" - PAGE 4 OF 3
<PAGE>   28

                         EXHIBIT "E" TO LEASE AGREEMENT

                        ACCEPTANCE OF PREMISES MEMORANDUM

       THIS ACCEPTANCE OF PREMISES MEMORANDUM (this "MEMORANDUM") is entered
into on this ____ day of October, 2000, by and between WIREDZONE PROPERTY, L.P.,
as Landlord ("LANDLORD"), and COMBIMATRIX CORPORATION, as Tenant ("TENANT").
Unless otherwise defined herein, all capitalized terms used herein shall have
the same meaning ascribed to such terms in the Lease (as hereinafter defined).

                                R E C I T A L S:

       WHEREAS, on October __, 2000, Landlord and Tenant entered into that
certain Lease Agreement (the "LEASE") whereby Landlord leased certain Premises
located in the Building to Tenant pursuant to certain terms and provisions more
particularly described therein;

       WHEREAS, as provided in Paragraph 8 of the Lease, Tenant desires to take
possession of and accept the Premises subject to the terms and provisions
hereof.

       NOW, THEREFORE, for and in consideration of the premises, and the mutual
covenants and agreements contained herein and in the Lease, Landlord and Tenant
hereby expressly covenant, acknowledge and agree as follows:

       1. Except as set forth in Exhibit "D" to the Lease, Landlord has no
further obligation to install or construct any leasehold improvements,
modifications or alterations to the Premises.

       2. The Commencement Date shall be November 1, 2000. Pursuant to the
provisions of the Lease, the first monthly installment of Base Rental shall
become due and payable on November 1, 2000.

       3. The expiration date of the Lease shall be October 31, 2008.

       4. The Premises contain 85,414 square feet of Rentable Space.

       5. Except as specifically set forth herein, as of the date of this
Memorandum the Lease has not been modified, altered, supplemented, superseded or
amended in any respect.

       6. All terms, provisions and conditions of the Lease are and remain in
full force and effect, and are hereby expressly ratified, confirmed, restated
and reaffirmed in each and every respect.

       IN WITNESS WHEREOF, this Memorandum is entered into by Landlord and
Tenant on the date first set forth above.

LANDLORD:                                   TENANT:
--------                                    ------

WIREDZONE PROPERTY, L.P.                    COMBIMATRIX CORPORATION

By:     WiredZone Property GenPar, LLC,
        its general partner                 By:
                                               ---------------------------------
                                            Its:
                                                --------------------------------

        By:
           ----------------------------
        Its:
            ---------------------------

                         EXHIBIT "F" TO LEASE AGREEMENT

                         BUILDING RULES AND REGULATIONS

       1. Sidewalks, doorways, vestibules, corridors, stairways and other
similar areas shall not be obstructed by Tenant or used by Tenant for any
purpose other than ingress and egress to and from the Premises and for going
from or to another part of the Building.

       2. Plumbing fixtures and appliances shall be used only for the purposes
for which designed, and no sweepings, rubbish, rags or other unsuitable
materials shall be thrown or placed therein. Damage resulting to any such
fixtures or appliances or surrounding areas from misuse by Tenant shall be
repaired at the sole cost and expense of Tenant, and Landlord shall not in any
case be responsible therefor.

       3. No signs, advertisements or notices shall be painted or affixed on or
to any windows or doors or other parts of the Building except of such color,
size and style and in such places as shall be first approved in writing by
Landlord. No nails, hooks or screws shall be driven or inserted in any part of
the Building which would impact Building systems except by the Building
maintenance personnel nor shall any part of the Building be defaced by Tenant.

                           EXHIBIT "E" - PAGE 1 OF 1
<PAGE>   29
       4. Tenant shall not place any additional lock or locks on any doors in or
to the Premises without Landlord's prior written consent. Two keys to the locks
on the doors which access the Premises from the Common Areas shall be furnished
by Landlord to Tenant, and Tenant shall not have any duplicate keys made.
Additional keys required by Tenant shall be made by Landlord at Tenant's sole
expense. Upon termination of the Lease, Tenant shall return all keys to Landlord
and shall provide to Landlord a means of opening all safes, cabinets and vaults
being left with the Premises.

       5. With respect to work being performed by Tenant in the Premises with
the approval of Landlord, Tenant will refer all contractors, contractor's
representatives and installation technicians rendering any service to them to
Landlord for Landlord's supervision, approval and control before the performance
of any contractual services. This provision shall apply to work performed in the
Building including, but not limited to, installation of telephones, telegraph
equipment, electrical devices and attachments, and any and all installation of
every nature affecting floors, walls, woodwork, trim, windows, ceilings,
equipment and any other physical portion of the Building. Tenant must have
Landlord's written approval prior to employing any contractor. Any and all such
contractors shall comply with these Rules and Regulations for such services
including, but not limited to, insurance requirements. All work in or on the
Building shall comply with any and all codes. (To the extent the terms and
conditions of this Rule 5 conflict with the terms and conditions of the
Leasehold Improvements Agreement, the terms and conditions of such Leasehold
Improvements Agreement shall control.)

       6. Movement in or out of the Building of furniture or office equipment,
or dispatch or receipt by Tenant of any bulky materials, merchandise or
materials which require use of elevators or stairways, or movement through the
Building entrances or lobby shall be restricted to such hours as Landlord shall
reasonably designate. All such movement shall be under the supervision of
Landlord and in the manner agreed between Tenant and Landlord by prearrangement
before performance. Such prearrangement initiated by Tenant will include
determination by Landlord, and subject to its decision and control, as to the
time, method and routing of movement and as to limitations for safety or other
concerns which may prohibit any article, equipment or any other item from being
brought into the Building. Tenant is to assume all risk as to damage to articles
moved and injury to person or public engaged or not engaged in such movement,
including equipment, property and personnel of Landlord and other tenants if
damaged or injured as a result of acts in connection with carrying out this
service for Tenant from the time of entering the property to completion of work;
and Landlord shall not be liable for acts of any person engaged in, or any
damage or loss to any of said property or persons resulting from any act in
connection with such service performed for Tenant.

       7. Landlord shall have the power to prescribe the weight and position of
safes and other heavy equipment, which shall, in all cases, be positioned to
distribute the weight and stand on supporting devices approved by Landlord. All
damage done to the Building by taking in or putting out any property of Tenant,
or done by Tenant's property while in the Building, shall be repaired at the
expense of Tenant.

       8. Corridor doors, when not in use, shall be kept closed.

       9. Tenant shall cooperate with Landlord's employees in keeping its
Premises neat and clean. Tenant shall not employ any person for the purpose of
such cleaning other than the Building's cleaning and maintenance personnel.
Landlord shall be in no way responsible to Tenant, its agents, employees,
contractors or invitees for any loss of property from the Premises or public
areas or for any damage to any property thereon from any cause whatsoever.

       10. To insure orderly operation of the Building, Landlord and Tenant
shall, prior to the Commencement Date, agree on reasonable rules and policies
respecting deliveries to the Premises on Tenant's behalf or required for
Tenant's operations.

       11. Should Tenant require telegraphic, telephonic, annunciator or other
communication service, Landlord will direct the electrician where and how wires
are to be introduced and placed and none shall be introduced or placed except as
Landlord shall direct. Electric current shall not be used for power in excess of
standard office use or heating without Landlord's prior written permission.

       12. Tenant shall not make or permit any improper noises in the Building
or otherwise interfere in any way with other tenants or persons having business
with them.

       13. Nothing shall be swept or thrown into the corridors, halls, elevator
shafts or stairways. No animals shall be brought into or kept in, on or about
the Premises.

       14. Tenant shall not permit its employees to install or utilize space
heaters in the Premises.

       15. No portion of the Premises shall at any time be used or occupied as
sleeping or lodging quarters.

       16. Landlord will not be responsible for money, jewelry or other personal
property lost or stolen in or from the Premises or public areas regardless of
whether such loss or theft occurs when the area is locked against entry or not.

       17. The Premises shall not be occupied by an average of more than one (1)
person per 200 square feet of Rentable Space in the Premises without the prior
written consent of Landlord.

       18. Landlord reserves the right to rescind any of these rules and
regulations and to make such other and further rules and regulations as in its
judgment shall from time to time be advisable for the safety, protection,
<PAGE>   30

care and cleanliness of the Building, the use and operation thereof, the
preservation of good order therein and the protection and comfort of the tenants
and their agents, employees and invitees, which rules and regulations, when made
and written notice thereof is given to Tenant, shall be binding upon Tenant in
like manner as if originally herein prescribed. No subsequent changes shall be
permitted to the extent they are inconsistent with the terms and conditions of
the Lease.

       19. Notwithstanding anything to the contrary contained herein, the
Building Rules and Regulations to be applied to Tenant shall in no event be less
favorable or adversely inconsistent with those applied to other tenants in the
Building.

                           EXHIBIT "F" - PAGE 3 OF 2

<PAGE>   31

                                                                   Rider No. 101

                               PARKING FACILITIES

        At all times during the Lease Term and any renewal or extension thereof,
and so long as this Lease and any renewal or extension thereof is in full force
and effect and no event of default shall have occurred and be continuing under
this Lease, Tenant shall be permitted the use of the surface parking lot
associated with the Building for parking automobiles owned by Tenant and its
employees, agents and invitees. Landlord hereby agrees to make available to
Tenant, and Tenant hereby agrees to take, subject to the further provisions of
this Rider No. 101, during the Lease Term, and any extension or renewal thereof,
all or some of the following permits to park automobiles on the surface parking
lot:

             A total of * permits for unassigned and unreserved parking in the
surface parking lot.

        Landlord and its parking lot operator shall have the right from time to
time to reconfigure the surface parking lot and to promulgate reasonable rules
and regulations regarding the parking permits available to Tenant hereunder and
others, including, but not limited to, the flow of traffic to and from various
parking areas, angles and direction of parking, and the like. Tenant agrees to
comply, and to cause its employees, agents and visitors to comply, with such
rules and regulations (and reasonable additions and amendments thereto) as
Landlord and its parking lot operator may promulgate from time to time. Landlord
and its parking lot operator will not be responsible for money, jewelry or other
personal property lost or stolen in or from the parking lot or public areas
regardless of whether such loss or theft occurs when the parking lot or such
area is locked or otherwise secured against entry or not.

* based on a ratio of 3.1 permits for every 1,000 square feet of Rentable Space
in the Premises for which Base Rental is being paid per Rider No. 106 hereto.

                                       1
<PAGE>   32

                                                                   Rider No. 102

                            TENANT'S OPTION TO RENEW

        Tenant may, at its option and subject to the terms hereof, renew the
Lease Term for two (2) additional term(s) of sixty (60) months each, provided
that this Lease must be in full force and effect and no event of default may
exist under this Lease at the time of exercise of such option or at the time the
renewal term would begin. Such renewal shall be upon the same terms and
conditions as provided elsewhere in this Lease, except that (i) this Lease may
not be renewed more often than as set forth above, (ii) Landlord shall have no
obligation to install improvements in the Premises, and (iii) the annual Base
Rental for such renewal period(s), and each monthly installment thereof, shall
be determined as provided below. Each such option shall be exercised by Tenant
giving notice to Landlord by certified mail, return receipt requested, at least
twelve (12) months prior to the end of the then-existing term, and, if not so
exercised, such option not so exercised and any subsequent option to renew shall
automatically expire and terminate. Notwithstanding anything to the contrary
contained herein, Tenant's option herein shall be subject to a determination by
Landlord, at Landlord's sole discretion, that Tenant's financial condition at
the time it makes such election is comparable or better than the financial
condition of Tenant at the time Tenant had executed this Lease (i.e., Tenant
must have a total equity capitalization at the time of each such renewal notice
of at least $50,000,000). If Tenant so elects to renew the Lease Term, following
Tenant's exercise of such renewal option, upon request from Landlord, Tenant and
Landlord will enter into a renewal agreement by which this Lease will be renewed
in accordance with the terms set forth in this Rider.

        The annual Base Rental for each renewal period shall be the Prevailing
Market Rental Rate for comparable buildings in the "North End Submarket of
Seattle" taking into consideration the unique features and location of the
Building, and the use, location and floor level within the Building for the
subject space as well as the intended term of such lease under consideration and
the date such renewal term is to commence. The Prevailing Market Rental Rate
shall be exclusive of the tenant improvements which are above the initial
Allowance under the Lease. The parties shall negotiate in good faith to
establish the Prevailing Market Rental Rate. If the parties are unable to agree
on such rate within thirty (30) days after Tenant gives Landlord is notice
exercising the Renewal Option (the "Notice Date"), then each party shall appoint
an appraiser who is a member of the American Institute of Real Estate Appraisers
(an "Appraiser") and has at least five (5) years experience appraising rental
properties in the greater Seattle area. If the Appraisers are unable to reach
agreement about Prevailing Market Rental Rate within forty-five (45) days after
the Notice Date, then either party on written notice to the other may request
appointment of a single arbitrator by the American Arbitration Association
("AAA") in accordance with its then prevailing real estate valuation arbitration
rules as modified by this Rider. Once the arbitrator is appointed, each
Appraiser shall promptly submit his/her determination of Prevailing Market
Rental Rate to the arbitrator. The arbitrator shall determine Prevailing Market
Rental Rate (applying the standards of determination set forth above) within ten
(10) days based solely on the materials submitted by the Appraisers and the
determination shall not exceed or be less than the Market Rent determinations of
the Appraisers. Each party shall bear the expense of retaining its Appraiser.
The fees and expenses of the arbitrator and other expenses of the arbitration
shall be borne equally by the parties. The arbitrator's determination of
Prevailing Market Rental Rate shall be final and binding on the parties.
Judgment upon the determination of Prevailing Market Rental Rate rendered by the
arbitrator may be entered into any court having jurisdiction over this matter.

                                       1
<PAGE>   33

                                                                   Rider No. 103

                                EXPANSION OPTION

        Provided (i) there is no event of default hereunder and (ii) Tenant's
total equity capitalization at the time of such expansion notice is at least
$50,000,000.00, Tenant shall have the right between the 48th and 50th month of
the Lease Term to provide Landlord with 18 months advance written notice of
Tenant's need for additional space equal to an amount up to 25% of the 85,414
actual square footage initially leased (the "Expansion Space"). If such notice
is given, Landlord shall and guarantees to provide Tenant with a solution for
accommodating said request. If the solution is within the Building, the term of
the lease with respect to such Expansion Space shall be coterminous with the
Lease Term for the original Premises. If the solution is in a structure to be
constructed as an addition to the Building or as another stand alone building
adjacent to the Building, then the term of the lease for the Expansion Space
shall be a minimum of seven years. In either case rental rates will be
negotiated based upon 100% of the then current market rents for similar space at
the time of the renewal notice by Tenant. The other terms and conditions
relating to such Expansion Space shall be substantially similar to those in the
Lease. The process for determining the fair market rent shall be as set forth in
Rider No. 102 to this Lease. In the event Tenant in its notice requires more
than 25% of the 85,414 actual square footage leased, Landlord shall use its best
efforts to provide a reasonably acceptable solution for Tenant in the Building,
any adjacent buildings or elsewhere. Said solution shall be mutually agreeable
to the parties with respect to location, timing and determination of fair market
rent.

                                       1
<PAGE>   34

                                                                   Rider No. 104

                           RIGHT OF FIRST OPPORTUNITY

        1. RIGHT OF FIRST OPPORTUNITY. Provided this Lease is then in full force
and effect and no event of default as defined in Paragraph 25 of this Lease has
occurred and remains uncured, and subject to the terms hereof, Tenant shall have
the right of first opportunity during the first sixty (60) months of the Lease
Term to lease all (or a portion) of the additional space consisting of the area
on the 2nd and 3rd floors designated and referred to on Exhibit "B-2" attached
to this Lease as the "RIGHT OF FIRST OPPORTUNITY SPACE", for a term beginning on
the Effective Date (as hereinafter defined) and ending contemporaneously with
the expiration of the Lease Term (unless sooner terminated pursuant to the terms
of this Lease, and subject to any rights of extension contained in this Lease).
The right of first opportunity contained herein shall automatically terminate
following the expiration of such sixty (60) month period (unless sooner
terminated pursuant to the terms of this Lease).

        2. NOTICE BY LANDLORD. Prior to entering into bona fide negotiations
with an existing tenant in the Building or a prospective tenant to lease all or
any part of the Right of First Opportunity Space (or if an existing tenant of
the Right of First Opportunity Space desires to extend the term of its lease
thereof), Landlord shall notify Tenant of such fact and shall include in such
notice the Prevailing Market Rental Rate for such space. Tenant shall have a
period of ten (10) business days from the date of delivery of such notice to
notify Landlord whether Tenant elects to exercise the right granted hereby to
lease such portion of the Right of First Opportunity Space. If Tenant fails to
give any notice to Landlord within the required ten (10) business day period,
Tenant shall be deemed to have refused its right to lease the Right of First
Opportunity Space. Notwithstanding anything to the contrary contained herein,
Tenant's option herein shall be subject to a determination by Landlord, in
Landlord's reasonable discretion, that Tenant's financial condition (i.e., total
equity capitalization at the time of such notice of at least $50,000,000) is
unchanged.

        3. REFUSAL BY TENANT. If Tenant so refuses its right to lease the Right
of First Opportunity Space (either by giving written notice thereof or by
failing to give any notice), Landlord shall have the right to lease all or any
portion of the Right of First Opportunity Space to an existing tenant in the
Building or a prospective tenant (or to extend the term of the lease of an
existing tenant) on such terms and provisions as may be acceptable to Landlord.
If Tenant so refuses its right to lease the Right of First Opportunity Space,
then if Landlord shall enter into a lease with a prospective tenant (or extend
the term of the lease of an existing tenant) for all or any part of the Right of
First Opportunity Space, Tenant's right of first opportunity as to such portion
of such Right of First Opportunity Space shall terminate with respect to that
lease but not with respect to future opportunities for the space in the event
such shall become available.

        4. ACCEPTANCE BY TENANT. Upon the exercise by Tenant of its right of
first opportunity as provided in Paragraph 2, Landlord and Tenant shall, within
ten (10) business days after Tenant delivers to Landlord notice of its election,
enter into a written amendment modifying and supplementing this Lease and
containing other appropriate terms and provisions relating to the addition of
the Right of First Opportunity Space to the Premises (including specifically any
increase, adjustment, or augmentation of rent as a result of such addition). The
annual Base Rental to be paid under this Lease for the Right of First
Opportunity Space so leased shall be at the Prevailing Market Rental Rate as
determined in the manner described in Rider No. 102 hereto. The payment of the
new Base Rental for the Right of First Opportunity Space shall commence on the
Effective Date, which shall be the later of (a) thirty (30) days following the
expiration date of the term of any lease with another tenant covering the Right
of First Opportunity Space, or (b) the date agreed upon by Landlord and Tenant
if the Right of First Opportunity Space is not covered by a prior tenant lease,
or, in the event they are unable to agree, shall be the date ninety (90) days
from the date upon which Tenant notified Landlord of its election to lease the
Right of First Opportunity Space. Rent for a partial month shall be prorated.
Possession of the Right of First Opportunity Space shall be delivered to Tenant
in an "as is" condition. Landlord shall not be liable for the failure to give
possession of the Right of First Opportunity Space on the Effective Date by
reason of the holding over or retention of possession of any tenant, tenants, or
occupants (provided Landlord uses commercially reasonable diligence in
prosecuting eviction of such tenant or occupant), or for any other reason, and
any such failure shall not impair the validity of this Lease, or extend the
Term, but the rent for such Right of First Opportunity Space shall be abated and
the Commencement Date extended until possession is delivered to Tenant, and such
abatement shall constitute full settlement of all claims that Tenant might
otherwise have against Landlord by reason of such failure to give possession of
the Right of First Opportunity Space to Tenant on the effective date.

        5. TERMINATION OF RIGHT. Any termination of this Lease during the
original Lease Term (or any extension thereof) or any non-permitted assignment
or subleasing by Tenant pursuant to this Lease shall terminate the right of
first opportunity of Tenant contained herein.

        6. SUBORDINATE RIGHT. [Intentionally Deleted.]

        7. ADDITIONAL RIGHT OF FIRST OPPORTUNITY. In addition to the right
described in Paragraph 2 above, Tenant shall have the right of first opportunity
to lease the entirety of any new structure or extension to the Building that
Landlord may construct on the land. Such right shall be for the first
eighty-four (84) months of the Lease Term. Rental rates shall be negotiated
based upon 100% of the then current market rents for similar space in the North
End Submarket at the time. The other terms and conditions relating to such new
structure or extension shall be substantially similar to those in the Lease. The
Prevailing Market Rental Rate shall be calculated using the methodology set
forth in Rider No. 102 to the Lease. In the event Tenant exercises this option
and leases the entire new structure or extension, then Tenant may relinquish the
entirety of its presence on the 3rd floor of the initial Premises.

                                       1
<PAGE>   35

                                                                   Rider No. 106

                             SCHEDULE OF BASE RENTAL

        Base Rental shall be payable as follows:

<TABLE>
<CAPTION>
                                                                           MONTHLY NNN
MONTHS                SIZE (RSF)              ANNUAL NNN RENT                  RENT
------                ----------              ---------------             --------------
<S>                   <C>                     <C>                         <C>
 1-10                   42,868                   $   **                     $   **

11-20                   63,537                   $   **                     $   **

21-24                   85,414                   $   **                     $   **

25-48                   85,414                   $   **                     $   **

49-72                   85,414                   $   **                     $   **

73-96                   85,414                   $   **                     $   **
</TABLE>

        ALTHOUGH TENANT INTENDS TO COMPLETE THE BUILD-OUT OF THE ENTIRE
PREMISES, IT IS INTENDED THAT TENANT WILL NOT UTILIZE CERTAIN PORTIONS OF THE
PREMISES UNTIL A LATER DATE. THE SCHEDULE OF BASE RENTAL SET FORTH ABOVE DEFINES
THE MINIMUM TAKE DOWN SCHEDULE OF SQUARE FOOTAGE IN THE PREMISES. SAID BASE
RENTAL SCHEDULE SHALL BE APPLICABLE REGARDLESS IF TENANT OCCUPIES AND USES LESS
THAN THE MINIMUM SPACE SET FORTH ABOVE; PROVIDED, HOWEVER, IF TENANT OCCUPIES
AND USES MORE THAN THE MINIMUM SQUARE FOOTAGE STATED ABOVE, TENANT SHALL BE
OBLIGATED TO PAY THE ADDITIONAL BASE RENTAL AND ADDITIONAL RENTAL (I.E.,
TENANT'S PROPORTIONATE SHARE OF OPERATING EXPENSES) ASSOCIATED WITH SUCH
ADDITIONAL SQUARE FOOTAGE. TENANT AGREES TO ADVISE LANDLORD AT ANY TIME THAT
TENANT USES SQUARE FOOTAGE IN EXCESS OF THE INTENDED TAKE DOWN SCHEDULE.
LANDLORD SHALL HAVE THE RIGHT, FROM TIME TO TIME, TO VERIFY TENANT'S ACTUAL
USAGE OF SPACE IN THE PREMISES AND SHALL ADVISE TENANT IF LANDLORD REASONABLY
BELIEVES THAT TENANT IS UTILIZING EXCESS SQUARE FOOTAGE FOR WHICH IT WILL
THEREAFTER BE CHARGED BASE RENTAL AND ADDITIONAL RENTAL HEREUNDER.

                                       1<PAGE>   1
                                                                    EXHIBIT 10.6

                               INDEMNITY AGREEMENT

        This Indemnity Agreement ("Agreement") is made and entered into by and
between CombiMatrix Corporation, a Delaware corporation ("Company"), and ______
("Indemnitee").

                                  Introduction

       Indemnitee is a director, officer or employee of the Company. The parties
desire that the Company provide indemnification (including advancement of
expenses) to Indemnitee against any and all liabilities asserted against
Indemnitee to the fullest extent permitted by the Delaware General Corporation
Law and any other law (including statutory law and law established by judicial
decision) of the State of Delaware (collectively, "Law"), as the Law presently
exists and may be expanded from time to time. Based on such premise, and for
certain good and valuable consideration, the receipt and sufficiency of which
are hereby acknowledged, the parties hereby agree as follows:

       1. Continued Service. Indemnitee will serve at the will of the Company or
under separate contract, if such exists, as a director and/or officer of the
Company for so long as Indemnitee is duly elected and qualified in accordance
with the Bylaws of the Company or until Indemnitee tenders Indemnitee's
resignation to the Company, or as an employee for so long as Indemnitee is
employed by the Company.

       2. Indemnification. The Company shall indemnify Indemnitee as follows:

              2.1 The Company shall indemnify Indemnitee when Indemnitee was or
is a party or is threatened to be made a party to any threatened, pending or
completed action, suit or proceeding, whether civil, criminal, administrative or
investigative (other than an action by or in the right of the Company), by
reason of the fact that Indemnitee is or was a director, officer, employee or
agent of the Company, or is or was serving at the request of the Company as a
director, officer, employee or agent of another corporation, partnership, joint
venture, trust or other enterprise, against expenses (including attorneys'
fees), judgments, fines and amounts paid in settlement actually and reasonably
incurred by Indemnitee in connection with such action, suit or proceeding
(including punitive and similar damages, to the extent permitted by Law) if
Indemnitee acted in good faith and in a manner Indemnitee reasonably believed to
be in or not opposed to the best interests of the Company, and, with respect to
any criminal action or proceeding, had no reasonable cause to believe that
Indemnitee's conduct was unlawful.

              2.2 The Company shall indemnify Indemnitee when Indemnitee was or
is a party or is threatened to be made a party to any threatened, pending or
completed action or suit by or in the right of the Company to procure a judgment
in its favor by reason of the fact that Indemnitee is or was a director,
officer, employee or agent of the Company, or is or was serving at the request
of the Company as a director, officer, employee or agent of another corporation,
partnership, joint venture, trust or other enterprise against expenses
(including attorneys' fees) actually and reasonably incurred by Indemnitee in
connection with the defense or settlement of

<PAGE>   2

such action or suit if Indemnitee acted in good faith and in a manner that
Indemnitee reasonably believed to be in or not opposed to the best interests of
the Company and except that no indemnification pursuant to this Agreement shall
be made in respect of any claim, issue or matter as to which Indemnitee shall
have been adjudged to be liable to the Company unless and only to the extent
that the Court of Chancery or the court in which such action or suit was brought
shall determine upon application that, despite the adjudication of liability but
in view of all the circumstances of the case, Indemnitee is fairly and
reasonably entitled to indemnity for such expenses which the Court of Chancery
or such other court shall deem proper.

              2.3 Any indemnification under Sections 2.1 and 2.2 (unless ordered
by a court) shall be made by the Company only as authorized in the specific case
upon a determination, in accordance with the procedures set forth in Section 3,
that indemnification of Indemnitee is proper in the circumstances because
Indemnitee has met the applicable standard of conduct set forth in such Sections
2.1 and 2.2. Subject to Section 3.3, such determination shall be made (1) by the
board of directors of the Company by a majority vote of a quorum consisting of
directors who were not parties to such action, suit or proceeding, or (2) if
such a quorum is not obtainable, or, even if obtainable a quorum of
disinterested directors so directs, by independent legal counsel in a written
opinion, or (3) by the stockholders of the Company.

              2.4 Expenses (including attorneys' fees) incurred by Indemnitee in
defending any civil, criminal, administrative, or investigative action, suit or
proceeding shall be paid from time to time by the Company in advance of the
final disposition of such action, suit or proceeding, within 14 days after the
receipt by the Company from Indemnitee of a Statement of Undertaking in
substantially the form set forth in Exhibit A, in which Indemnitee (1) states
that Indemnitee has reasonably incurred actual expenses in defending a civil,
criminal, administrative, or investigative action, suit or proceeding and (2)
undertakes to repay such amount if it shall ultimately be determined that
Indemnitee is not entitled to be indemnified by the Company as authorized in
this Section 2.

              2.5 The indemnification and advancement of expenses provided by,
or granted pursuant to, this Section 2 shall not be deemed exclusive of any
other rights to which Indemnitee may be entitled under any bylaw, agreement,
vote of stockholders or disinterested directors, Law or otherwise, both as to
action in Indemnitee's official capacity and as to action in another capacity
while holding such office, shall continue after Indemnitee has ceased to be a
director, officer, employee or agent of the Company, and shall inure to the
benefit of the heirs, executors and administrators of Indemnitee.

              2.6 The termination of any action, suit or proceeding by judgment,
order, settlement or conviction or upon a plea of nolo contendere or its
equivalent shall not, of itself, create a presumption that Indemnitee did not
act in good faith and in a manner which Indemnitee reasonably believed to be in
or not opposed to the best interests of the Company, and, with respect to any
criminal action or proceeding, had reasonable cause to believe that Indemnitee's
conduct was unlawful.

       3. Determination of Right to Indemnification. For the purpose of making
the determination of whether to indemnify Indemnitee in a specific case under
Section 2.3, the board of directors of the Company, independent legal counsel or
stockholders, as the case may be, shall make the determination in accordance
with the following procedures:

                                       2
<PAGE>   3

              3.1 Indemnitee shall submit to the board of directors a Statement
of Request for Indemnification in substantially the form set forth in Exhibit B,
in which Indemnitee states that Indemnitee has met the applicable standard of
conduct set forth in Sections 2.1 and 2.2.

              3.2 Indemnitee's submission of a Statement of Request for
Indemnification to the board of directors shall create a rebuttable presumption
that Indemnitee has met the applicable standard of conduct set forth in Sections
2.1 and 2.2 and, therefore, is entitled to indemnification under Section 2. The
board of directors, independent legal counsel or stockholders, as the case may
be, shall determine, within 45 days after submission of the Statement of Request
for Indemnification, specifically that Indemnitee is so entitled, unless it or
they shall possess clear and convincing evidence to rebut the foregoing
presumption, which evidence shall be disclosed to Indemnitee with particularity
in a sworn written statement signed by all persons who participated in the
determination and voted to deny indemnification.

              3.3 At Indemnitee's option, Indemnitee may elect that the
determination as to indemnification is to be made by Independent Counsel (as
defined below), in which event the Independent Counsel shall be selected by
Indemnitee, and Indemnitee shall give written notice to the Company
("Independent Counsel Notice") within 10 days after the delivery of the
Statement of Request for Indemnification advising it of the identity of the
Independent Counsel so selected (unless Indemnitee shall request in the
Independent Counsel Notice that such selection be made by the board of directors
of the Company), in which event the Company shall give written notice to
Indemnitee within 10 days after receipt of Indemnitee's Independent Counsel
Notice advising Indemnitee of the identity of the Independent Counsel so
selected). In either event, Indemnitee or the Company, as the case may be, may,
within seven days after such written notice of selection shall have been given,
deliver to the Company or to Indemnitee, as the case may be, a written objection
to such selection. Any objection to selection of Independent Counsel pursuant to
this Section 3.3 may be asserted only on the ground that the Independent Counsel
so selected does not meet the requirements of the definition of "Independent
Counsel" below, and the objection shall set forth with particularity the factual
basis of such assertion. If such written objection is timely made, the
Independent Counsel so selected may not serve as Independent Counsel unless and
until a court has determined that such objection is without merit. In the event
of a timely written objection to a choice of Independent Counsel, the party
originally selecting the Independent Counsel shall have seven days to make an
alternate selection of Independent Counsel and to give written notice of such
selection to the other party, after which time such other party shall have seven
days to make a written objection to such alternate selection. If, within 45 days
after submission by Indemnitee of a Statement of Request for Indemnification
pursuant to Section 3.1 hereof, no Independent Counsel shall have been selected
and not objected to, either the Company or Indemnitee may petition a court of
competent jurisdiction (the "Court") for resolution of any objections that shall
have been made by the Company or Indemnitee to the other's selection of
Independent Counsel and/or for the appointment as Independent Counsel of a
person selected by the Court or by such other person as the Court shall
designate, and the person with respect to whom an objection is so resolved or
the person so appointed shall act as Independent Counsel for purposes of the
determination to be made under Section 2.3 hereof. The Company shall pay any and
all reasonable fees and expenses of Independent Counsel incurred by such
Independent Counsel in connection with acting pursuant to hereto and provide
such person with appropriate indemnification, and the Company shall pay all
reasonable fees and expenses incident to the procedures of this Section 3.3,
regardless of the manner in which such Independent Counsel was selected or
appointed. The rights and

                                       3
<PAGE>   4

obligations of the parties under this Section 3.3 shall be subject to, and shall
be given effect only to the extent permitted by, applicable Law.

              3.4 If the person or persons empowered or selected under this
Agreement to determine whether Indemnitee is entitled to indemnification shall
not have made a determination within 45 days after receipt by the Company of the
Statement of Request for Indemnification by Indemnitee therefor (or, if the
determination of entitlement to indemnification is to be made by Independent
Counsel pursuant to Section 3.3 of this Agreement, and such determination shall
not have been made and delivered in written opinion within 90 days after (i)
such Independent Counsel's being appointed, (ii) the overruling by the Court of
objections to such Counsel's selection or (iii) expiration of all periods for
the Company or Indemnitee to object to such Counsel's selection), the requisite
determination of entitlement to indemnification shall be deemed to have been
made and Indemnitee shall be entitled to such indemnification, absent a
prohibition of such indemnification under applicable Law; provided, however,
that such 45-day period may be extended for a reasonable time, not to exceed an
additional 30 days, if the person making the determination with respect to
entitlement to indemnification in good faith requires such additional time for
the obtaining or evaluating of documentation and/or information relating to such
determination; and provided, further, that the 45-day limitation set forth in
this Section 3.4 shall not apply and such period shall be extended as necessary
if Independent Counsel is not to make the determination pursuant to section 3.3
of this Agreement and if within 30 days after receipt by the Company of the
Statement of Request for Indemnification the Board has resolved to submit such
determination to the stockholders for their consideration at an annual meeting
thereof to be held within 90 days after such receipt and such determination is
made thereat, or a special meeting of stockholders is called within 30 days
after such receipt for the purpose of making such determination, such meeting is
held for such purpose within 60 days after having been so called and such
determination is made thereat.

       4. Merger, Consolidation or Change in Control. If the Company is a
constituent corporation in a merger or consolidation, whether the Company is the
resulting or surviving corporation or is absorbed as a result thereof, or if
there is a change in control of the Company, or a sale or other complete
disposition of all or substantially all of the assets of the Company, Indemnitee
shall stand in the same position under this Agreement with respect to the
resulting, surviving, changed or acquiring corporation or other entity as
Indemnitee would have with respect to the Company if its separate existence had
continued or if there had been no change in the control of the Company or a sale
or other complete disposition of all or substantially all of the assets of the
Company.

       5. Certain Definitions. For the purposes of this Agreement, the following
terms shall have the indicated meanings and understandings:

              5.1 The term "other enterprise" shall include, among others,
employee benefit plans and civic, non-profit and charitable organizations,
whether or not incorporated.

              5.2 The term "fines" shall include any excise taxes assessed on
Indemnitee with respect to any employee benefit plan.

              5.3 The term "serving at the request of the Company" shall include
any service, at the request or with the express or implied authorization of the
Company, as a director, officer, employee or agent of another corporation,
partnership, joint venture, trust or other enter-

                                       4
<PAGE>   5

prise, which service imposes duties on, or involves services by, Indemnitee with
respect to such corporation, partnership, joint venture, trust or other
enterprise, its participants or beneficiaries. If Indemnitee acted in good faith
and in a manner Indemnitee reasonably believed to be in or not opposed to the
best interests of such other enterprise, its participants or beneficiaries,
Indemnitee shall be deemed to have acted in a manner not opposed to the best
interests of the Company.

              5.4 The term "change of control" shall include any change in the
ownership of a majority of the outstanding voting securities of the Company or
in the composition of a majority of the members of the board of directors of the
Company.

              5.5 The term "Independent Counsel" means a law firm, or a member
of a law firm, that is experienced in matters of corporation law and neither
contemporaneously is, nor in the five years theretofore has been, retained to
represent: (a) the Company or Indemnitee in any matter material to either such
party, (b) any other party to the proceeding giving rise to a claim for
indemnification hereunder or (c) the beneficial owner, directly or indirectly,
of securities of the Company representing 25% or more of the combined voting
power of the Company's then outstanding voting securities. Notwithstanding the
foregoing, the term "Independent Counsel" shall not include any person who,
under the applicable standards of professional conduct then prevailing, would
have a conflict of interest in representing either the Company or Indemnitee in
an action to determine Indemnitee's rights under this Agreement.

       6. Attorneys' Fees. If Indemnitee institutes any legal action to enforce
Indemnitee's rights under this Agreement, or to recover damages for breach of
this Agreement, Indemnitee, if Indemnitee prevails in whole or in part, shall be
entitled to recover from the Company all fees and expenses (including attorneys'
fees) incurred by Indemnitee in connection therewith.

       7. Deposit of Funds In Trust. If the Company voluntarily decides to
dissolve or to file a petition for relief under the applicable bankruptcy,
moratorium or similar laws, then not later than 10 days prior to such
dissolution or filing, the Company shall deposit in trust for the sole and
exclusive benefit of Indemnitee a cash amount equal to all amounts previously
authorized to be paid to Indemnitee hereunder, such amounts to be used to
discharge the Company's obligations to Indemnitee hereunder. Any amounts in such
trust not required for such purpose shall be returned to the Company. This
Section 7 shall not apply to the dissolution of the Company in connection with a
transaction as to which Section 4 applies.

       8. Amendments to Law. This Agreement is intended to provide indemnity to
Indemnitee to the fullest extent allowed under Law, including but not limited to
statutory law and judicial decisions. Accordingly, to the extent permitted by
Law, if the Law permits greater indemnity than the indemnity set forth herein,
or if any amendment is made to any Law expanding the indemnity permissible under
Law, the indemnity obligations contained herein automatically shall be expanded,
without the necessity of action on the part of any party, to the extent
necessary to provide to Indemnitee the fullest indemnity permissible under Law.

                                       5
<PAGE>   6

       9. Miscellaneous Provisions.

              9.1 This Agreement shall continue for so long as Indemnitee serves
as a director of the Company or as a director, officer, partner, employee, agent
or fiduciary of any other corporation, partnership, joint venture, trust,
employee benefit plan or other enterprise in which the Indemnitee served at the
request of the Company, and thereafter shall survive until and terminate upon
the later to occur of: (a) the final termination of all pending proceedings in
respect of which Indemnitee is granted rights of indemnification or advancement
of expenses hereunder and of any proceeding commenced by Indemnitee relating
thereto; or (b) the expiration of all statutes of limitation applicable to
possible claims arising out of Indemnitee's services as described above. This
Agreement shall be binding upon the Company and its successors and assigns and
shall inure to the benefit of Indemnitee and Indemnitee's heirs, executors,
legal representatives and administrators.

              9.2 This Agreement constitutes the full understanding of the
parties and a complete and exclusive statement of the terms and conditions of
this Agreement and supersedes all prior negotiations, understandings and
agreements, whether written or oral, between the parties, their affiliates, and
their respective principals, shareholders, directors, officers, employees,
consultants and agents with respect thereto; provided, however, that no rights
of Indemnitee under any certificate of incorporation, bylaw, insurance policy,
Law or other agreement shall be limited or terminated by this Agreement.

              9.3 No alteration, modification, amendment, change or waiver of
any provision of this Agreement shall be effective or binding on any party
hereto unless the same is in writing and is executed by all parties hereto.

              9.4 If a court of competent jurisdiction declares that any
provision of this Agreement is illegal, invalid or unenforceable, then such
provision shall be modified automatically to the extent necessary to make such
provision fully legal, valid or enforceable. If such court does not modify any
such provision as contemplated herein, but instead declares it to be wholly
illegal, invalid or unenforceable, then such provision shall be severed from
this Agreement, this Agreement and the rights and obligations of the parties
hereto shall be construed as if this Agreement did not contain such severed
provision, and this Agreement otherwise shall remain in full force and effect.

              9.5 This Agreement shall be enforceable by and against the
Company, the Indemnitee and their respective executors, legal representatives,
administrators, heirs, successors and assignees.

              9.6 This Agreement shall be governed by, construed under, and
enforced in accordance with the laws of the State of Delaware without reference
to the conflict-of-laws provisions thereof.

              9.7 This Agreement may be executed by the parties hereto in
multiple counterparts, each of which shall be deemed an original for all
purposes, and all of which together shall constitute one and the same
instrument.

                                       6
<PAGE>   7

              9.8 The Company shall be precluded from asserting in any judicial
proceeding commenced under this Agreement that the procedures and presumptions
of this Agreement are not valid, binding and enforceable and shall stipulate in
any such court that the Company is bound by all the provisions of this
Agreement.

              9.9 Unless otherwise expressly provided herein, all notices,
requests, demands, consents, waivers, instructions, approvals and other
communications hereunder shall be in writing and shall be deemed to have been
duly given if personally delivered to or mailed, certified mail return receipt
requested, first-class postage paid, addressed as follows:

               If to the Company, to it at:

               CombiMatrix Corporation
               34935 SE Douglas Ave., Suite 110
               Snoqualmie, WA 98065
               Attn:  General Counsel
               With a copy to the President

               If to Indemnitee, to Indemnitee at:

               ------------------------------------

               ------------------------------------

               ------------------------------------

               ------------------------------------

or to such other address or to such other addressees as any party shall have
last designated as its address or addressee by notice to the other party. All
notices and other communications given to any party in accordance with the
provisions of this Agreement shall be deemed to have been given when delivered
or sent to the intended recipient thereof in accordance with the provisions of
this Section 9.9.

                                       7
<PAGE>   8

The parties hereto have executed this Agreement effective as of ___________,
2000.

                                    COMPANY:

                                    COMBIMATRIX CORPORATION

                                    By:
                                       -----------------------------------------
                                    Name:
                                         ---------------------------------------
                                    Title:
                                          --------------------------------------

                                    INDEMNITEE:

                                    By:
                                       -----------------------------------------

                                       8
<PAGE>   9

                                    EXHIBIT A

                            STATEMENT OF UNDERTAKING

STATE OF __________________    Section
                               Section
COUNTY OF _________________    Section

       I, __________________________________, being first duly sworn, depose and
say as follows:

       1. This Statement of Undertaking is submitted pursuant to the Indemnity
Agreement dated ______________, between _____________________, a Delaware
corporation ("Company"), and me.

       2. I am requesting the advancement of certain actual expenses which I
have reasonably incurred in defending a civil or criminal action, suit or
proceeding by reason of the fact that I am or was a director, officer, employee
or agent of the Company or I am serving or have served at the request of the
Company as a director, officer, employee or agent of another corporation,
partnership, joint venture, trust or other enterprise.

       3. I hereby undertake to repay this advancement of expenses if it is
ultimately determined that I am not entitled to be indemnified by the Company.

       4. I am requesting the advancement of expenses in connection with the
following action, suit or proceeding:

       I have executed this Statement of Undertaking on _____________________.

                                                 -------------------------------
                                                 Signature

                                                 -------------------------------
                                                 Print Name

       Subscribed and sworn to before me on ___________________.

                                                 -------------------------------
                                                 Notary Public in and for
                                                   said state and county
                                                 My commission expires:_________

                                       9
<PAGE>   10

                                    EXHIBIT B

                    STATEMENT OF REQUEST FOR INDEMNIFICATION

STATE OF __________________     Section
                                Section
COUNTY OF _________________     Section

       I, ___________________________________, being first duly sworn, depose
and say as follows:

       1. This Statement of Request for Indemnification is submitted pursuant to
the Indemnity Agreement dated _________________, between ____________________, a
Delaware corporation ("Company"), and me.

       2. I am requesting indemnification against expenses (including attorneys'
fees) and, with respect to any action not by or in the right of the Company,
judgments, fines and amounts paid in settlement, all of which have been actually
and reasonably incurred by me in connection with a certain action, suit or
proceeding to which I am a party or am threatened to be made a party by reason
of the fact that I am or was a director, officer, employee or agent of the
Company or I am serving or have served at the request of the Company as a
director, officer, employee or agent of another corporation, partnership, joint
venture, trust or other enterprise.

       3. With respect to all matters related to any such action, suit or
proceeding, I acted in good faith and in a manner I reasonably believed to be in
or not opposed to the best interests of the Company, and, with respect to any
criminal action or proceeding, I had no reason to believe that my conduct was
unlawful.

       4. I am requesting indemnification in connection with the following suit,
action or proceeding:

       I have executed this Statement of Request for Indemnification on
______________________.

                                                 -------------------------------
                                                 Signature

                                                 -------------------------------
                                                 Print Name

<PAGE>   11

       Subscribed and sworn to before me on ___________________.

                                                 -------------------------------
                                                 Notary Public in and for
                                                   said state and county
                                                 My Commission expires:_________

                                      -12-

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