Document:

exv10w3

Exhibit 10.3

REAFFIRMATION OF GUARANTY

          THIS REAFFIRMATION OF GUARANTY (this “Reaffirmation”) is made as of August 7, 2009 and
entered into by MARTHA STEWART LIVING OMNIMEDIA, INC., a Delaware corporation (“Parent
Guarantor”), and each of its subsidiaries listed on the signature pages to this Reaffirmation
(together with Parent Guarantor, the “Guarantors”). Capitalized terms used herein but not
otherwise defined herein shall have the meanings ascribed to such terms in the Amended and Restated
Loan Agreement (as defined below).

W I T N E S S E T H:

          WHEREAS, MSLO Emeril Acquisition Sub LLC, a Delaware limited liability company (the
“Borrower”), Parent Guarantor and Bank of America, N.A. (the “Bank”) entered into
that certain Loan Agreement dated as of April 4, 2008 (the “Existing Loan Agreement”);

          WHEREAS, in connection with the Existing Loan Agreement, each of the Guarantors executed and
delivered a Continuing and Unconditional Guaranty dated April 4, 2008 (the “Guaranty”);

          WHEREAS, the Existing Loan Agreement is being amended and restated by the Amended and
Restated Loan Agreement dated as of August 7, 2009 (the “Amended and Restated Loan
Agreement”); and

          WHEREAS, as a condition precedent to the effectiveness of the Amended Loan Agreement, the
Lenders have required that each Guarantor enter into this Reaffirmation to ratify and reaffirm its
obligations under the Guaranty.

          NOW THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are
hereby acknowledged, the parties hereto agree as follows:

     Section 1. Reaffirmation of Guaranty.

               (a) Each Guarantor hereby acknowledges receipt of a copy of the Amended and Restated Loan
Agreement and consents to the execution and delivery of the Amended and Restated Loan Agreement by
the Borrower and Parent Guarantor and all other agreements, instruments and other documents
executed in connection therewith. In connection with the execution and delivery of the Amended and
Restated Loan Agreement and the Security Agreement Amendment, each Guarantor hereby acknowledges
and agrees that (i) the Guaranty remains and will remain in full force and effect during the term
of the Amended and Restated Loan Agreement (including any further renewals, amendments,
restatements, supplements or other modifications of the Amended and Restated Loan Agreement made
from time to time) or, if later, so long as any of the Obligations under the Amended and Restated
Loan Agreement remain

 

 

2

outstanding and (ii) ratifies and reaffirms all of its obligations, contingent or otherwise,
under the Guaranty.

     Section 2. No Consent Required. Each Guarantor, other than Parent Guarantor,
acknowledges and agrees that (i) notwithstanding any consent granted by it under this
Reaffirmation, such Guarantor is not required by the terms of the Existing Loan Agreement or any
other Loan Document to consent to the amendments contemplated under the Amended and Restated Loan
Agreement and the Security Agreement Amendment and (ii) nothing in the Existing Loan Agreement, the
Security Agreement Amendment or any other Loan Document shall be deemed to require the consent of
such Guarantor to any future amendments to any of the Existing Loan Agreement or the Amended and
Restated Loan Agreement.

     Section 3. Further Assurances. Each Guarantor hereby agrees from time to time, as
and when requested by the Agent, to execute and deliver or cause to be executed and delivered all
such documents, instruments and agreements, and to take or cause to be taken such further or other
actions, as the Agent may deem necessary in order to carry out the intent and purposes of this
Master Reaffirmation and the Loan Documents.

     Section 4. Release. In consideration of the agreements of the Bank contained in
the Amended and Restated Loan Agreement and for other good and valuable consideration, the receipt
and sufficiency of which is hereby acknowledged, each of the Guarantors, on behalf of itself and
its successors, assigns and other legal representatives, hereby absolutely, unconditionally and
irrevocably releases, remises and forever discharges the Bank (in its individual capacity and in
its capacity as Collateral Agent) and its successors and assigns, and its present and former
shareholders, affiliates, subsidiaries, divisions, predecessors, directors, officers, attorneys,
employees, agents and other representatives (the Bank and all such other Persons being hereinafter
referred to collectively as the “Releasees” and individually as a “Releasee”), of
and from all demands, actions, causes of action, suits, damages and any and all other claims,
counterclaims, defenses, rights of set-off, demands and liabilities whatsoever of every name and
nature, known or unknown, both at law and in equity, such Guarantor, or any of its successors,
assigns or other legal representatives may now or hereafter own, hold, have or claim to have
against the Releasees or any of them for, upon, or by reason of any circumstance, action, cause or
thing whatsoever which arises at any time on or prior to the day and date of this Agreement for or
on account of, or in relation to, or in any way in connection with any of the Existing Loan
Agreement, any of the other Loan Documents or any transactions thereunder or related thereto.

     Section 5. Successors and Assigns. This Reaffirmation shall be binding upon, and
shall inure to the benefit of, the parties hereto and their respective successors and permitted
assigns.

     Section 6. Counterparts. This Reaffirmation may be executed in any number of
counterparts and by different parties hereto in separate counterparts, each of

 

 

3

which shall be deemed to be an original, but all of which taken together shall constitute one
and the same agreement.

     Section 7. Headings. Section headings herein are included for convenience of
reference only and shall not constitute a part of this Reaffirmation for any other purpose.

     Section 8. Governing Law. This Reaffirmation shall be governed by, and construed
in accordance with, the laws of the State of New York.

     Section 9. Reaffirmation as Loan Document. Each of the Guarantors hereby
acknowledges and agrees that this Reaffirmation constitutes a “Loan Document.”

[Remainder of this page intentionally left blank.]

 

 

          IN WITNESS WHEREOF, this Reaffirmation has been duly executed as of the
day and year first above written.

	 	 	 	 	 
	 	MARTHA STEWART LIVING OMNIMEDIA, INC.

 	 
	 	By:  	/s/ Charles Koppelman
 	 
	 	 	Name:  	Charles Koppelman 	 
	 	 	Title:  	Principal Executive Officer 	 
	 
	 	MSO IP HOLDINGS, INC.

 	 
	 	By:  	/s/ Charles Koppelman
 	 
	 	 	Name:  	Charles Koppelman 	 
	 	 	Title:  	President 	 
	 
	 	MARTHA STEWART, INC.

 	 
	 	By:  	/s/ Charles Koppelman
 	 
	 	 	Name:  	Charles Koppelman 	 
	 	 	Title:  	President 	 
	 
	 	BODY AND SOUL OMNIMEDIA, INC.

 	 
	 	By:  	/s/ Charles Koppelman
 	 
	 	 	Name:  	Charles Koppelman 	 
	 	 	Title:  	President 	 
	 
	 	MSLO PRODUCTIONS, INC.

 	 
	 	By:  	/s/ Charles Koppelman
 	 
	 	 	Name:  	Charles Koppelman 	 
	 	 	Title:  	President 	 
	 

[Signature page to Reaffirmation of Guaranty]

 

 

	 	 	 	 	 
	 	MSLO PRODUCTIONS – HOME, INC.

 	 
	 	By:  	/s/ Charles Koppelman
 	 
	 	 	Name:  	Charles Koppelman 	 
	 	 	Title:  	President 	 
	 
	 	MSLO PRODUCTIONS – EDF, INC.

 	 
	 	By:  	/s/ Charles Koppelman
 	 
	 	 	Name:  	Charles Koppelman 	 
	 	 	Title:  	President 	 
	 
	 	FLOUR PRODUCTIONS, INC.

 	 
	 	By:  	/s/ Charles Koppelman
 	 
	 	 	Name:  	Charles Koppelman 	 
	 	 	Title:  	President 	 
	 

[Signature page to Reaffirmation of Guaranty]exv10w1

Exhibit 10.1

LEASE

BETWEEN

METROPOLITAN LIFE INSURANCE COMPANY (LANDLORD)

AND

GENOMIC HEALTH, INC. (TENANT)

SEAPORT CENTRE 

Redwood City, California

 

 

TABLE OF CONTENTS

	 	 	 	 	 
	 	 	PAGE
	ARTICLE ONE — BASIC LEASE PROVISIONS
	 	 	1	 
	1.01 BASIC LEASE PROVISIONS
	 	 	1	 
	1.02 ENUMERATION OF EXHIBITS & RIDER(S)
	 	 	2	 
	1.03 DEFINITIONS
	 	 	2	 
	 
	 	 	 	 
	ARTICLE TWO — PREMISES, TERM, FAILURE TO GIVE POSSESSION, COMMON AREAS AND PARKING
	 	 	6	 
	2.01 LEASE OF PREMISES
	 	 	6	 
	2.02 TERM
	 	 	6	 
	2.03 FAILURE TO GIVE POSSESSION
	 	 	6	 
	2.04 AREA OF PREMISES
	 	 	6	 
	2.05 CONDITION OF PREMISES
	 	 	6	 
	2.06 COMMON AREAS & PARKING
	 	 	6	 
	 
	 	 	 	 
	ARTICLE THREE — RENT
	 	 	7	 
	 
	 	 	 	 
	ARTICLE FOUR — OPERATING EXPENSES RENT ADJUSTMENTS AND PAYMENTS
	 	 	7	 
	4.01 TENANT’S SHARE OF OPERATING EXPENSES
	 	 	7	 
	4.02 RENT ADJUSTMENTS
	 	 	7	 
	4.03 STATEMENT OF LANDLORD
	 	 	8	 
	4.04 BOOKS AND RECORDS
	 	 	8	 
	4.05 TENANT OR LEASE SPECIFIC TAXES
	 	 	8	 
	 
	 	 	 	 
	ARTICLE FIVE — SECURITY
	 	 	8	 
	 
	 	 	 	 
	ARTICLE SIX
— UTILITIES & SERVICES
	 	 	10	 
	6.01 LANDLORD’S GENERAL SERVICES
	 	 	10	 
	6.02 TENANT TO OBTAIN & PAY DIRECTLY
	 	 	10	 
	6.03 TELEPHONE SERVICES
	 	 	10	 
	6.04 FAILURE OR INTERRUPTION OF UTILITY OR SERVICE
	 	 	10	 
	6.05 INTENTIONALLY OMITTED
	 	 	11	 
	6.06 SIGNAGE
	 	 	11	 
	 
	 	 	 	 
	ARTICLE SEVEN — POSSESSION, USE AND CONDITION OF PREMISES
	 	 	11	 
	7.01 POSSESSION AND USE OF PREMISES
	 	 	11	 
	7.02 HAZARDOUS MATERIAL
	 	 	11	 
	7.03 LANDLORD ACCESS TO PREMISES; APPROVALS
	 	 	13	 
	7.04 QUIET ENJOYMENT
	 	 	13	 
	 
	 	 	 	 
	ARTICLE
EIGHT — MAINTENANCE & HVAC
	 	 	13	 
	8.01 LANDLORD’S MAINTENANCE
	 	 	13	 
	8.02 TENANT’S MAINTENANCE
	 	 	14	 
	 
	 	 	 	 
	ARTICLE NINE — ALTERATIONS AND IMPROVEMENTS
	 	 	14	 
	9.01 TENANT ALTERATIONS
	 	 	14	 
	9.02 LIENS
	 	 	15	 
	 
	 	 	 	 
	ARTICLE TEN — ASSIGNMENT AND SUBLETTING
	 	 	15	 
	10.01 ASSIGNMENT AND SUBLETTING
	 	 	15	 
	10.02 RECAPTURE
	 	 	17	 
	10.03 EXCESS RENT
	 	 	17	 
	10.04 TENANT LIABILITY
	 	 	17	 
	10.05 ASSUMPTION AND ATTORNMENT
	 	 	17	 
	 
	 	 		 
	ARTICLE ELEVEN — DEFAULT AND REMEDIES
	 	 	18	 
	11.01 EVENTS OF DEFAULT
	 	 	18	 
	11.02 LANDLORD’S REMEDIES
	 	 	18	 
	11.03 ATTORNEY’S FEES
	 	 	19	 
	11.04 BANKRUPTCY
	 	 	20	 
	11.05 LANDLORD’S DEFAULT
	 	 	20	 
	 
	 	 	 	 
	ARTICLE TWELVE — SURRENDER OF PREMISES
	 	 	20	 
	12.01 IN GENERAL
	 	 	20	 
	12.02 LANDLORD’S RIGHTS
	 	 	21	 
	 
	 	 	 	 
	ARTICLE THIRTEEN — HOLDING OVER
	 	 	21	 
	 
	 	 	 	 
	ARTICLE FOURTEEN — DAMAGE BY FIRE OR OTHER CASUALTY
	 	 	21	 
	14.01 SUBSTANTIAL UNTENANTABILITY
	 	 	21	 

i 

 

	 	 	 	 	 
	 	 	PAGE
	14.02 INSUBSTANTIAL UNTENANTABILITY
	 	 	22	 
	14.03 RENT ABATEMENT
	 	 	22	 
	14.04 WAIVER OF STATUTORY REMEDIES
	 	 	22	 
	 
	 	 	 	 
	ARTICLE FIFTEEN — EMINENT DOMAIN
	 	 	22	 
	15.01 TAKING OF WHOLE OR SUBSTANTIAL PART
	 	 	22	 
	15.02 TAKING OF PART
	 	 	22	 
	15.03 COMPENSATION
	 	 	22	 
	 
	 	 	 	 
	ARTICLE SIXTEEN — INSURANCE
	 	 	23	 
	16.01 TENANT’S INSURANCE
	 	 	23	 
	16.02 FORM OF POLICIES
	 	 	23	 
	16.03 LANDLORD’S INSURANCE
	 	 	23	 
	16.04 WAIVER OF SUBROGATION
	 	 	23	 
	16.05 NOTICE OF CASUALTY
	 	 	24	 
	 
	 	 	 	 
	ARTICLE SEVENTEEN — WAIVER OF CLAIMS AND INDEMNITY
	 	 	24	 
	17.01 WAIVER OF CLAIMS
	 	 	24	 
	17.02 INDEMNITY BY TENANT
	 	 	24	 
	17.03 WAIVER OF CONSEQUENTIAL DAMAGES
	 	 	24	 
	 
	 	 	 	 
	ARTICLE EIGHTEEN — RULES AND REGULATIONS
	 	 	25	 
	18.01 RULES
	 	 	25	 
	18.02 ENFORCEMENT
	 	 	25	 
	 
	 	 	 	 
	ARTICLE NINETEEN — LANDLORD’S RESERVED RIGHTS
	 	 	25	 
	 
	 	 	 	 
	ARTICLE TWENTY — ESTOPPEL CERTIFICATE
	 	 	25	 
	20.01 IN GENERAL
	 	 	25	 
	20.02 ENFORCEMENT
	 	 	25	 
	 
	 	 	 	 
	ARTICLE TWENTY-ONE — INTENTIONALLY OMITTED
	 	 	26	 
	 
	 	 	 	 
	ARTICLE TWENTY-TWO — REAL ESTATE BROKERS
	 	 	26	 
	 
	 	 	 	 
	ARTICLE TWENTY-THREE — MORTGAGEE PROTECTION
	 	 	26	 
	23.01 SUBORDINATION AND ATTORNMENT
	 	 	26	 
	23.02 MORTGAGEE PROTECTION
	 	 	26	 
	 
	 	 	 	 
	ARTICLE TWENTY-FOUR — NOTICES
	 	 	26	 
	 
	 	 	 	 
	ARTICLE TWENTY-FIVE — EXERCISE FACILITY
	 	 	27	 
	 
	 	 	 	 
	ARTICLE
TWENTY-SIX — MISCELLANEOUS
	 	 	27	 
	26.01 LATE CHARGES
	 	 	27	 
	26.02 NO JURY TRIAL; VENUE; JURISDICTION
	 	 	27	 
	26.03 DEFAULT UNDER OTHER LEASE
	 	 	28	 
	26.04 OPTION
	 	 	28	 
	26.05 TENANT AUTHORITY
	 	 	28	 
	26.06 ENTIRE AGREEMENT
	 	 	28	 
	26.07 MODIFICATION OF LEASE FOR BENEFIT OF MORTGAGEE
	 	 	28	 
	26.08 EXCULPATION
	 	 	28	 
	26.09 ACCORD AND SATISFACTION
	 	 	28	 
	26.10 LANDLORD’S OBLIGATIONS ON SALE OF BUILDING
	 	 	28	 
	26.11 BINDING EFFECT
	 	 	28	 
	26.12 CAPTIONS
	 	 	29	 
	26.13 TIME;
APPLICABLE LAW; CONSTRUCTION
	 	 	29	 
	26.14 ABANDONMENT
	 	 	29	 
	26.15 LANDLORD’S RIGHT TO PERFORM TENANT’S DUTIES
	 	 	29	 
	26.16 SECURITY SYSTEM
	 	 	29	 
	26.17 NO
LIGHT, AIR OR VIEW EASEMENTS
	 	 	29	 
	26.18 RECORDATION
	 	 	29	 
	26.19 SURVIVAL
	 	 	29	 
	26.20 EXHIBITS OR RIDERS
	 	 	30	 

ii 

 

LEASE

ARTICLE ONE

BASIC LEASE PROVISIONS

1.01 BASIC LEASE PROVISIONS

In the event of any conflict between these Basic Lease Provisions and any other Lease
provision, such other Lease provision shall control.

	(1)	 	BUILDING AND ADDRESS:
	 
	 	 	Building Number 6, located in Phase I (“Tenant’s Phase”) of Seaport Centre. As of the
Date of Lease, the Building has a street address of 301 Chesapeake Drive, Redwood
City, California 94063
	 
	(2)	 	LANDLORD AND ADDRESS:
	 
	 	 	Metropolitan Life Insurance
Company, 

a New York corporation
	 
	 	 	Notices to Landlord shall be addressed:

Metropolitan Life
Insurance Company 
c/o
Seaport Centre Manager
 701
Chesapeake Drive
 Redwood
City, CA 94063

with copies to the following:

Metropolitan Life Insurance
Company
 425 Market Street,
Suite 1050
 San Francisco,
CA 94105
 Attention:
Director, EIM

               and

Metropolitan Life Insurance
Company
 425 Market Street,
Suite 1050
 San Francisco,
CA 94105
 Attention:
Associate General Counsel

	(3)	 	TENANT; CURRENT ADDRESS & TAX ID:

	 	 	 	 	 
	(a)

	 	Name:
	 	Genomic Health, Inc. (“Genomic Health”)
	(b)

	 	State of incorporation:
	 	a Delaware corporation
	(c)

	 	Tax Identification Number:
	 	77-0552594 
	 
	Tenant shall notify Landlord of any change in the foregoing.
	 
	 	 	 	 
	Notices to Tenant shall be addressed:
	 
	 	 	 	 
	 

	 	Genomic Health, Inc.	 	 
	 

	 	301 Penobscot Drive	 	 
	 

	 	Redwood City, CA 94063	 	 
	 

	 	Attention: Chief Financial Officer	 	 

	(4)	 	DATE OF LEASE: as of OCT 1 - 2009
	 
	(5)	 	LEASE TERM: Eight (8) years.
	 
	(6)	 	COMMENCEMENT DATE: the earlier of occupancy for business or April 1, 2010, subject to
Rider 2.
	 
	(7)	 	EXPIRATION DATE: The day before the eighth (8th) anniversary of the
Commencement Date.
	 
	(8)	 	MONTHLY BASE RENT: The initial monthly installment is due upon Tenant’s execution.

	 	 	 	 	 	 	 	 	 
	Period from Commencement	 	 	 	 
	Date through Expiration Date	 	Monthly	 	Monthly Rate/SF of Rentable Area
	Months 01 – 12

	 	$	49,455.36	 	 	$	1.62	 
	Months 13 – 24

	 	$	50,981.76	 	 	$	1.67	 
	Months 25 – 36

	 	$	52,508.16	 	 	$	1.72	 
	Months 37 – 48

	 	$	54,034.56	 	 	$	1.77	 
	Months 49 – 60

	 	$	55,560.96	 	 	$	1.82	 
	Months 61 – 72

	 	$	57,392.64	 	 	$	1.88	 
	Months 73 – 84

	 	$	59,224.32	 	 	$	1.94	 
	Months 85 – 96

	 	$	61,056.00	 	 	$	2.00	 

1

 

(9) RENT ADJUSTMENT DEPOSIT: The Rent Adjustment Deposit (at the initial monthly rate, until further
notice) shall be Thirteen Thousand Three Hundred Sixteen Dollars ($13,316.00) and is due upon
Tenant’s execution.

	(10)	 	RENTABLE AREA OF THE PREMISES: 30,528 square feet
	 
	(11)	 	RENTABLE AREA OF THE BUILDING 30,528 square feet
	 
	(12)	 	RENTABLE AREA OF THE PHASE: 301,835 square feet
	 
	(13)	 	RENTABLE AREA OF THE PROJECT: 537,444 square feet
	 
	(14)	 	SECURITY: The cash and/or Letter of Credit in the amount of One Hundred Eighty-three Thousand
One Hundred Sixty-eight Dollars ($183,168.00) (and any proceeds of the Letter of Credit drawn
and held by Landlord) as provided in Article Five.
	 
	(15)	 	SUITE NUMBER &/OR ADDRESS OF PREMISES: 301 Chesapeake Drive, Redwood City, CA 94063

	 
	(16)	 	TENANT’S SHARE:

	 	 	 	 	 
	Tenant’s Building Share:

	 	 	100.00	%
	Tenant’s Phase Share:

	 	 	10.114	%
	Tenant’s Project Share:

	 	 	5.680	%

	(17)	 	TENANT’S USE OF PREMISES: General office use; biotechnology/pharmaceutical research and
development, assembly, biotechnical or pharmaceutical manufacturing, and warehousing.
	 
	(18)	 	PARKING SPACES: 101
	 
	(19)	 	BROKERS:

	 	 	 
	Landlord’s Broker:

	 	Cornish & Carey Commercial
	 
	Tenant’s Broker:

	 	GVA Kidder Mathews

1.02 ENUMERATION OF EXHIBITS & RIDER(S)

The Exhibits and Rider(s) set forth below and attached to this Lease are incorporated in this
Lease by this reference:

EXHIBIT A Plan of Premises

EXHIBIT B Workletter Agreement

EXHIBIT C Site Plan of Project

EXHIBIT D Permitted Hazardous Material

EXHIBIT E Form of Letter of Credit Acceptable from Silicon Valley Bank

EXHIBIT F Fair Market Rental Rate

EXHIBIT G Tenant’s Personal Property

EXHIBIT H Form of Letter of Credit

EXHIBIT I Outline of Expansion Space — 701 Galveston Drive

RIDER 1 Commencement Date Agreement

RIDER 2 Additional Provisions

1.03 DEFINITIONS

For purposes hereof, the following terms shall have the following meanings:

ADJUSTMENT YEAR: The applicable calendar year or any portion thereof after the Commencement Date
of this Lease for which a Rent Adjustment computation is being made.

AFFILIATE: Any Person (as defined below) which is controlled by, controls, or is under common
control with Tenant. The word Person means an individual, partnership, trust, corporation, limited
liability company, firm or other entity. For purposes of this definition, the word “control,”
means, with respect to a Person that is a corporation or a limited liability company, the right to
exercise, directly or indirectly, more than sixty percent (60%) of the voting rights attributable
to the shares or membership interests of the controlled Person and, with respect to a Person that
is not a corporation, the possession, directly or indirectly, of the power at all times to direct
or cause the direction of the management of the controlled Person.

BUILDING: Each building in which the Premises is located, as specified in Section
1.01(1). 

BUILDING OPERATING EXPENSES: Those Operating Expenses described in
Section 4.01.

COMMENCEMENT DATE: The date specified in Section 1.01(6) as the Commencement Date, unless changed
by operation of Article Two or Rider 2.

2

 

COMMON AREAS: All areas of the Project made available by Landlord from time to time for the
general common use or benefit of the tenants of the Building or Project, and their employees and
invitees, or the public, as such areas currently exist and as they may be changed from time to
time.

DECORATION: Tenant Alterations which do not require a building permit and which do not affect the
facade or roof of the Building, or involve any of the structural elements of the Building, or
involve any of the Building’s systems, including its electrical, mechanical, plumbing, security,
heating, ventilating, air-conditioning, communication, and fire and life safety systems.

DEFAULT RATE: Two (2) percentage points above the rate then most recently announced by Bank of
America N.T. & S.A. at its San Francisco main office as its corporate base lending rate, from time
to time announced, but in no event higher than the maximum rate permitted by Law.

DELIVERY DATE: The date for Landlord’s delivery to Tenant of possession of the Premises, if
different from the Commencement Date, as provided in Rider 2.

ENVIRONMENTAL LAWS: All Laws governing the use, storage, disposal or generation of any Hazardous
Material or pertaining to environmental conditions on, under or about the Premises or any part of
the Project, including the Comprehensive Environmental Response Compensation and Liability Act of
1980, as amended (42 U.S.C. Section 9601 et  seq.), and the Resource Conservation and Recovery Act
of 1976, as amended (42 U.S.C. Section 6901 et seq.).

EXPIRATION DATE: The date specified in Section 1.01(7) unless changed by operation of Article Two
or Rider 2.

FORCE MAJEURE: Any accident, casualty, act of God, war or civil commotion, strike or labor
troubles, or any cause whatsoever beyond the reasonable control of Landlord, including water
shortages, energy shortages or governmental preemption in connection with an act of God, a
national emergency, or by reason of Law, or by reason of the conditions of supply and demand which
have been or are affected by act of God, war or other emergency.

HAZARDOUS MATERIAL: Such substances, material and wastes which are or become regulated under any
Environmental Law; or which are classified as hazardous or toxic or medical waste or biohazardous
waste under any Environmental Law; and explosives, firearms and ammunition, flammable material,
radioactive material, asbestos, polychlorinated biphenyls and petroleum and its byproducts.

INDEMNITEES: Collectively, Landlord, any Mortgagee or ground lessor of the Property, the property
manager and the leasing manager for the Property and their respective directors, officers, agents
and employees.

LAND: The parcel(s) of real estate on which the Building and Project are located.

LANDLORD WORK: The construction or installation of improvements to be furnished by Landlord, if
any, specifically described in Rider 2 attached hereto.

LAWS OR LAW: All laws, ordinances, rules, regulations, other requirements, orders, rulings or
decisions adopted or made by any governmental body, agency, department or judicial authority
having jurisdiction over the Property, the Premises or Tenant’s activities at the Premises and any
covenants, conditions or restrictions of record which affect the Property.

LEASE: This instrument and all exhibits and riders attached hereto, as may be amended from time to
time.

LEASE YEAR: The twelve month period beginning on the first day of the first month following the
Commencement Date (unless the Commencement Date is the first day of a calendar month in which case
beginning on the Commencement Date), and each subsequent twelve month, or shorter, period until
the Expiration Date.

MONTHLY BASE RENT: The monthly rent specified in Section 1.01(8).

MORTGAGEE: Any holder of a mortgage, deed of trust or other security instrument encumbering the
Property.

NATIONAL HOLIDAYS: New Year’s Day, Memorial Day, Independence Day, Labor Day, Thanksgiving Day and
Christmas Day and other holidays recognized by the Landlord and the janitorial and other unions
servicing the Building in accordance with their contracts.

OPERATING EXPENSES: All Taxes, costs, expenses and disbursements of every kind and nature which
Landlord shall pay or become obligated to pay in connection with the ownership, management,
operation, maintenance, replacement and repair of the Property (including the amortized portion of
any capital expenditure or improvement, together with interest thereon, expenses of changing
utility service providers, and any dues, assessments and other expenses pursuant to any covenants,
conditions and restrictions, or any reciprocal easements, or any owner’s association now or
hereafter affecting the Project; provided however that with respect to any expenses, dues,
assessments and other expenses pursuant to any covenants, conditions and restrictions, or any
reciprocal easements, or any owner’s association hereafter affecting the Project, then such costs
and expenses shall only be deemed to be Operating Expenses to the extent that such costs or
expenses could otherwise be deemed to be Operating Expenses pursuant to the provisions set forth
in this section). Operating Expenses shall be allocated among the categories of Project Operating
Expenses, Building Operating Expenses or Phase Operating Expenses as provided in Article Four. If
any Operating Expense relates to more than one calendar year, such expense shall be
proportionately allocated among such related calendar years. Operating Expenses shall include the
following, by way of illustration only and not limitation: (1) all Taxes; (2) all insurance
premiums and other costs (including deductibles), including the cost of rental insurance; (3) all
license, permit and

3

 

inspection fees; (4) all costs of utilities, fuels and related services, including water,
sewer, light, telephone, power and steam connection, service and related charges; (5) all
costs to repair, maintain and operate heating, ventilating and air conditioning systems,
including preventive maintenance incurred by Landlord, if any; (6) all janitorial, landscaping
and security services; (7) all wages, salaries, payroll taxes, fringe benefits and other labor
costs, including the cost of workers’ compensation and disability insurance; (8) all costs of
operation, maintenance and repair of all parking facilities and other common areas; (9) all
supplies, materials, equipment and tools; (10) dues, assessments and other expenses pursuant
to any covenants, conditions and restrictions, or any reciprocal easements, or any owner’s
association now or hereafter affecting the Project; (11) modifications to the Building or the
Project occasioned by Laws now or hereafter in effect, but only as amortized over the useful
life of the capital item as reasonably determined by Landlord; (12) the total charges of any
independent contractors employed in the care, operation, maintenance, repair, leasing and
cleaning of the Project, including landscaping, roof maintenance, and repair, maintenance and
monitoring of life-safety systems, plumbing systems, electrical wiring and Project signage;
(13) the cost of accounting services necessary to compute the rents and charges payable by
tenants at the Project;
(14) exterior window and exterior wall cleaning and painting; (15) managerial and administrative
expenses; (16) all costs in connection with the exercise facility at the Project; (17) all costs
and expenses related to Landlord’s retention of consultants in connection with the routine
review, inspection, testing, monitoring, analysis and control of Hazardous Material, and
retention of consultants in connection with the clean-up of Hazardous Material (to the extent not
recoverable from a particular tenant of the Project), and all costs and expenses related to the
implementation of recommendations made by such consultants concerning the use, generation,
storage, manufacture, production, storage, release, discharge, disposal or clean-up of Hazardous
Material on, under or about the Premises or the Project (to the extent not recoverable from a
particular tenant of the Project); (18) all capital improvements made for the purpose of reducing
or controlling other Operating Expenses, and all other capital expenditures, but only as
amortized over the useful life of such capital improvement as reasonably determined by Landlord,
together with interest on the unamortized portion; (19) all property management costs and fees,
including all costs in connection with the Project property management office; and (20) all fees
or other charges incurred in conjunction with voluntary or involuntary membership in any energy
conservation, air quality, environmental, traffic management or similar organizations. Operating
Expenses shall not include: (a) costs of alterations of space to be occupied by new or existing
tenants of the Project; (b) depreciation charges; (c) interest and principal payments on loans
(except for loans for capital expenditures or improvements which Landlord is allowed to include
in Operating Expenses as provided above); (d) ground rental payments; (e) real estate brokerage
and leasing commissions; (f) advertising and marketing expenses; (g) costs of Landlord reimbursed
by insurance proceeds; (h) costs for which the Landlord is reimbursed by any other tenant or
occupant of the Building (other than payments comparable to Rent Adjustments hereunder) or by any
tenant’s insurance carrier or by anyone else, and electric power costs for which any tenant
directly contracts with the local public service company; (i)  expenses incurred in negotiating
leases of other tenants in the Project or enforcing lease obligations of other tenants in the
Project; (j) Landlord’s property manager’s corporate general overhead or corporate general
administrative expenses; (k) the wages and benefits of any employee who does not devote
substantially all of his or her employed time to the Building, Project or Phase, unless such
wages and benefits are prorated to reflect time spent on operation and managing the Building,
Project or Phase; (I) Landlord’s corporate general overhead or corporate general administrative
expenses associated with the operation of the business of the entity which constitutes the
Landlord, as the same are
distinguished from the costs of operation of the Building, Project or Phase; (m)
executives’ salaries; (n) any bad debt loss, rent loss, or reserves for bad debts or rent
loss; (o) costs of Landlord’s charitable or political contributions; (p) the costs of any
Tenant Work (as defined in the Workletter), and (q) costs incurred in connection with
Hazardous Materials to the extent such Hazardous Materials were present on the Project
prior to the Delivery Date.

PHASE: Phase means any individual Phase of the Project, as more particularly described in the
definition of Project.

PHASE OPERATING EXPENSES: Those Operating Expenses described in Section 4.01.

PREMISES: The Premises consists of the portion of the Building consisting of 30,528 square
feet of Rentable Area as depicted on Exhibit A attached hereto.

PROJECT or PROPERTY: As of the date hereof, the Project is known as Seaport Centre and consists
of those buildings (including the Building) whose general location is shown on the Site Plan of
the Project attached as Exhibit C, located in Redwood City, California, associated
vehicular and parking areas, landscaping and improvements, together with the Land, any associated
interests in real property, and the personal property, fixtures,  machinery, equipment, systems
and apparatus located in or used in conjunction with any of the foregoing. The Project may also
be referred to as the Property. As of the date hereof, the Project is divided into Phase I and
Phase II, which are generally designated on Exhibit C, each of which may individually be
referred to as a Phase. Landlord reserves the right from time to time to add or remove buildings,
areas and improvements to or from a Phase or the Project, or to add or remove a Phase to or from
the Project. In the event of any such addition or removal which affects Rentable Area of the
Project or a Phase, Landlord shall make a corresponding recalculation and adjustment of any
affected Rentable Area and Tenant’s Share.

PROJECT OPERATING EXPENSES: Those Operating Expenses described in Section 4.01.

REAL PROPERTY: The Property excluding any personal property.

RENT: Collectively, Monthly Base Rent, Rent Adjustments and Rent Adjustment Deposits, and all
other charges, payments, late fees or other amounts required to be paid by Tenant under this
Lease.

RENT ADJUSTMENT: Any amounts owed by Tenant for payment of Operating Expenses. The Rent
Adjustments shall be determined and paid as provided in Article Four.

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RENT ADJUSTMENT DEPOSIT: An amount equal to Landlord’s estimate of the Rent Adjustment
attributable to each month of the applicable Adjustment Year. On or before the Commencement Date
and the beginning of each subsequent Adjustment Year or with Landlord’s Statement (defined in
Article Four), Landlord may estimate and notify Tenant in writing of its estimate of Operating
Expenses, including Project Operating Expenses, Building Operating Expenses and Phase Operating
Expenses, and Tenant’s Share of each, for the applicable Adjustment Year. The Rent Adjustment
Deposit applicable for the calendar year in which the Commencement Date occurs shall be the
amount, if any, specified in Section 1.01(9). Nothing contained herein shall be construed to limit
the right of Landlord from time to time during any calendar year to revise its estimates of
Operating Expenses and to notify Tenant in writing thereof and of revision by prospective
adjustments in Tenant’s Rent Adjustment Deposit payable over the remainder of such year. The last
estimate by Landlord shall remain in effect as the applicable Rent Adjustment Deposit unless and
until Landlord notifies Tenant in writing of a change.

RENTABLE AREA OF THE BUILDING: The amount of square footage set forth in Section 1.01(11)

RENTABLE AREA OF THE PHASE: The amount of square footage set forth in Section 1.01(12)

RENTABLE AREA OF THE PREMISES: The amount of square footage set forth in Section 1.01(10).

RENTABLE AREA OF THE PROJECT: The amount of square footage set forth in Section 1.01(13), which
represents the sum of the rentable area of all space intended for occupancy in the Project.

SECURITY: The cash and/or Letter of Credit specified in Section 1.01, if any, paid or delivered to
Landlord as security for Tenant’s performance of its obligations under this Lease, and any
proceeds of the Letter of Credit drawn and held by Landlord, all as more particularly provided in
Article Five.

SUBSTANTIALLY COMPLETE: The completion of the Landlord Work or Tenant Work, as the case may be,
except for minor insubstantial details of construction, decoration or mechanical adjustments which
remain to be done.

TAXES: All federal, state and local governmental taxes, assessments (including assessment bonds)
and charges of every kind or nature, whether general, special, ordinary or extraordinary, which
Landlord shall pay or become obligated to pay because of or in connection with the ownership,
leasing, management, control or operation of the Property or any of its components (including any
personal property used in connection therewith), which may also include any rental or similar taxes
levied in lieu of or in addition to general real and/or personal property taxes. For purposes
hereof, Taxes for any year shall be Taxes which are assessed for any period of such year, whether
or not such Taxes are billed and payable in a subsequent calendar year. There shall be included in
Taxes for any year the amount of all fees, costs and expenses (including reasonable attorneys’
fees) paid by Landlord during such year in seeking or obtaining any refund or reduction of Taxes.
Taxes for any year shall be reduced by the net amount of any tax refund received by Landlord
attributable to such year. If a special assessment payable in installments is levied against any
part of the Property, Taxes for any year shall include only the installment of such assessment and
any interest payable or paid during such year. Taxes shall not include any federal or state
inheritance, general income, gift or estate taxes, except that if a change occurs in the method of
taxation resulting in whole or in part in the substitution of any such taxes, or any other
assessment, for any Taxes as above defined, such substituted taxes or assessments shall be included
in the Taxes.

TENANT ADDITIONS: Collectively, Landlord Work, Tenant Work and Tenant Alterations. Tenant’s
Personal Property (as set forth in Exhibit G hereto) shall not be deemed to be included in
the definition of Tenant Additions.

TENANT ALTERATIONS: Any alterations, improvements, additions, installations or construction in or
to the Premises or any Real Property systems serving the Premises done or caused to be done by
Tenant after the date hereof, whether prior to or after the Commencement Date (including Tenant
Work, but excluding Landlord Work).

TENANT DELAY: Any event or occurrence which delays the Substantial Completion of the Landlord Work
which is caused by or is described as follows:

(i) special work, changes, alterations or additions requested or made by Tenant in the
design or finish in any part of the Premises after approval of the plans and specifications
(as described in the Rider 2);

(ii) Tenant’s delay in submitting plans, supplying information, approving plans,
specifications or estimates, giving authorizations or otherwise;

(iii) failure to approve and pay for such work as Landlord undertakes to complete at
Tenant’s expense;

(iv) the performance or completion by Tenant or any person engaged by Tenant of any work in
or about the Premises; or

(v) failure to perform or comply with any obligation or condition binding upon Tenant
pursuant to Rider 2, including the failure to approve and pay for such Landlord Work or
other items if and to the extent Rider 2 provides they are to be approved or paid by
Tenant.

TENANT’S FF&E: The property of Tenant described in Section 5 of the
Workletter.

TENANT’S PERSONAL PROPERTY: Tenant’s property described on
Exhibit G hereto.

TENANT WORK: All work installed or furnished to the Premises by Tenant in connection with Tenant’s
initial occupancy pursuant to Rider 2 and the Workletter.

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TENANT’S BUILDING SHARE: The share as specified in Section 1.01(16) and Section 4.01.

TENANT’S PHASE: The Phase in which the Premises is located, as indicated in Section
1.01(1).

TENANT’S PHASE SHARE: The share as specified in Section 1.01(16) and Section
4.01.

TENANT’S PROJECT SHARE: The share as specified in Section 1.01(16) and Section
4.01.

TENANT’S SHARE: Shall mean collectively, Tenant’s respective shares of the respective categories
of Operating Expenses, as provided in Section 1.01(16) and Section 4.01.

TERM: The term of this Lease commencing on the Commencement Date and expiring on the Expiration
Date.

TERMINATION DATE: The Expiration Date or such earlier date as this Lease terminates or Tenant’s
right to possession of the Premises terminates.

WORKLETTER: The Agreement regarding the completion of Tenant Work and Landlord Work, if any, set
forth in Rider 2 and Exhibit B hereto.

ARTICLE TWO

PREMISES, TERM, FAILURE TO GIVE POSSESSION, COMMON AREAS AND PARKING

2.01 LEASE OF PREMISES

Landlord hereby leases to Tenant and Tenant hereby leases from Landlord the Premises for the Term
and upon the terms, covenants and conditions provided in this Lease.

2.02 TERM (See Rider 2)

2.03 FAILURE TO GIVE POSSESSION (See Rider 2)

2.04 AREA OF PREMISES

Landlord and Tenant agree that for all purposes of this Lease the Rentable Area of the Premises,
the Rentable Area of the Building, the Rentable Area of the Phase and the Rentable Area of the
Project as set forth in Article One are controlling, and are not subject to revision after the
date of this Lease, except as otherwise provided herein.

2.05 CONDITION OF PREMISES (See Rider 2)

2.06 COMMON AREAS & PARKING

     (a) Right to Use Common Areas. Tenant shall have the non-exclusive right, in common
with others, to the use of any common entrances, ramps, drives and similar access and serviceways
and other Common Areas in the Project. The rights of Tenant hereunder in and to the Common Areas
shall at all times be subject to the rights of Landlord and other tenants and owners in the Project
who use the same in common with Tenant, and it shall be the duty of Tenant to keep all the Common
Areas free and clear of any obstructions created or permitted by Tenant or resulting from Tenant’s
operations. Tenant shall not use the Common Areas or common facilities of the Building or the
Project, including the Building’s electrical room, parking lot or trash enclosures, for storage
purposes. Nothing herein shall affect the right of Landlord at any time to remove any persons not
authorized to use the Common Areas or common facilities from such areas or facilities or to prevent
their use by unauthorized persons.

     (b) Changes in Common Areas. Landlord reserves the right, at any time and from time to
time to (i) make alterations in or additions to the Common Areas or common facilities of the
Project, including constructing new buildings or changing the location, size, shape or number of
the driveways, entrances, parking spaces, parking areas, loading and unloading areas, landscape
areas and walkways, (ii) designate property to be included in or eliminate property from the Common
Areas or common facilities of the Project, (iii) close temporarily any of the Common Areas or
common facilities of the Project for maintenance purposes, and (iv) use the Common Areas and common
facilities of the Project while engaged in making alterations in or additions and repairs to the
Project; provided, however, that (x) such changes do not materially adversely affect Tenant’s use
of the Premises or increase Tenant’s costs hereunder, and (y) reasonable access to the Premises and
parking at or near the Project remains available.

     (c) Parking. During the Term, Tenant shall have the right to use the number of Parking
Spaces specified in Section 1.01(18) for parking on an unassigned basis on that portion of the
Project designated by Landlord from time to time for parking. Tenant acknowledges and agrees that
the parking spaces in the Project’s parking facility may include a mixture of spaces for compact
vehicles as well as full-size passenger automobiles, and that Tenant shall not use parking spaces
for vehicles larger than the striped size of the parking spaces. Tenant shall comply with any and
all parking rules and regulations if and as from time to time established by Landlord. Tenant shall
not allow any vehicles using Tenant’s parking privileges to be parked, loaded or unloaded except in
accordance with this Section, including in the areas and in the manner designated by Landlord for
such activities. If any vehicle owned or operated by Tenant or any Tenant Parties (as defined in
Article Seven) is using the parking or loading areas contrary to any provision of this Section,
Landlord shall have the right, in addition to all other rights and remedies of Landlord under this
Lease, to remove or tow away the vehicle without prior notice to Tenant, and the cost thereof shall
be paid to Landlord within ten (10) business days after notice from Landlord to Tenant.

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ARTICLE THREE

RENT

Tenant agrees to pay to Landlord via wire transfer in accordance with instructions set forth below
(as modified by Landlord from time to time), or to such other persons, or at such other places or
in such manner designated by Landlord, without any prior demand therefor in immediately available
funds and without any deduction or offset whatsoever, Rent, including Monthly Base Rent and Rent
Adjustments in accordance with Article Four, during the Term. Monthly Base Rent shall be paid
monthly in advance on the first day of each month of the Term, except that the first installment
of Monthly Base Rent shall be paid by Tenant to Landlord concurrently with execution of this Lease
by means of Tenant’s check payable to the order of Metropolitan Life Insurance Company. Monthly
Base Rent shall be prorated for partial months within the Term. Unpaid Rent shall bear interest at
the Default Rate from the date due until paid. Tenant’s covenant to pay Rent shall be independent
of every other covenant in this Lease. Until further notice to Tenant, Rent paid by wire transfer
shall be wired to:

Bank: Wells Fargo Bank

Bank City, State: San Francisco, CA

Bank account name: CBRE ITF Metropolitan Life Insurance Seaport Centre l

Wire routing number: 121000248

Account number: 482-9605815

ARTICLE FOUR

OPERATING EXPENSES, RENT ADJUSTMENTS AND PAYMENTS

4.01 TENANT’S SHARE OF OPERATING EXPENSES

Tenant shall pay Tenant’s Share of Operating Expenses in the respective shares of the respective
categories of Operating Expenses as set forth below.

     (a) Tenant’s Project Share of Project Operating Expenses, which is the percentage
obtained by dividing the rentable square footage of the Premises by the rentable square
footage of the Project and as of the date hereof equals the percentage set forth in Section
1.01(16);

     (b) Tenant’s Building Share of Building Operating Expenses, which is the percentage
obtained by dividing the rentable square footage of the Premises respectively for each
building in which the Premises is located by the total rentable square footage of such
building and as of the date hereof equals the percentage set forth in Section 1.01(16);

     (c) Tenant’s Phase Share of Phase Operating Expenses, which is the percentage obtained
by dividing the aggregate rentable square footage of the Premises by the total rentable
square footage of Tenant’s Phase and as of the date hereof equals the percentage set forth
in Section 1.01(16);

     (d) Project Operating Expenses shall mean all Operating Expenses that are not included
as Phase Operating Expenses (defined below) and that are not either Building Operating
Expenses or operating expenses directly and separately identifiable to the operation,
maintenance or repair of any other building located in the Project, but Project Operating
Expenses includes operating expenses allocable to any areas of the Building or any other
building during such time as such areas are made available by Landlord for the general
common use or benefit of all tenants of the Project, and their employees and invitees, or
the public, as such areas currently exist and as they may be changed from time to time;

     (e) Building Operating Expenses shall mean Operating Expenses that are directly and
separately identifiable to each building in which the Premises or part thereof is located;

     (f) Phase Operating Expenses shall mean Operating Expenses that Landlord may allocate
to a Phase as directly and separately identifiable to all buildings located in the Phase
(including but not limited to the Building) and may include Project Operating Expenses that
are separately identifiable to a Phase;

     (g) Landlord shall have the right to allocate a particular item or portion of Operating
Expenses as any one of Project Operating Expenses, Building Operating Expenses or Phase
Operating Expenses; however, in no event shall any portion of Building Operating Expenses,
Project Operating Expenses or Phase Operating Expenses be assessed or counted against Tenant
more than once; and

     (h) Notwithstanding anything to the contrary contained in this Section 4.01, as to each
specific category of Operating Expense which one or more tenants of the Building either pays
directly to third parties or specifically reimburses to Landlord (for example, separately
contracted janitorial services or property taxes directly reimbursed to Landlord), then, on
a category by category basis, the amount of Operating Expenses for the affected period shall
be adjusted as follows: (1) all such tenant payments with respect to such category of
expense and all of Landlord’s costs reimbursed thereby shall be excluded from Operating
Expenses and Tenant’s Building Share, Tenant’s Phase Share or Tenant’s Project Share, as the
case may be, for such category of Operating Expense shall be adjusted by excluding the
square footage of all such tenants, and (2) if Tenant pays or directly reimburses Landlord
for such category of Operating Expense, such category of Operating Expense shall be excluded
from the determination of Operating Expenses for the purposes of this Lease.

4.02 RENT ADJUSTMENTS

Tenant shall pay to Landlord Rent Adjustments with respect to each Adjustment Year as follows:

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     (a) The Rent Adjustment Deposit shall be paid monthly during the Term with the payment of
Monthly Base Rent, except the first installment which shall be paid by Tenant to Landlord
concurrently with execution of this Lease. The Rent Adjustment Deposit represents, on a
monthly basis, Tenant’s Share of Landlord’s estimate of Operating Expenses, as described in
Section 4.01, for the applicable Adjustment Year (or portion thereof); and

     (b) Any Rent Adjustments due in excess of the Rent Adjustment Deposits in accordance
with Section 4.03.

4.03 STATEMENT OF LANDLORD

Within one hundred twenty (120) days after the end of each calendar year or as soon thereafter as
reasonably possible, Landlord will furnish Tenant a statement (“Landlord’s Statement”) showing the
following:

     (a) Operating Expenses for the last Adjustment Year showing in reasonable detail the
actual Operating Expenses categorized among Project Operating Expenses, Building Operating
Expenses and Phase Operating Expenses for such period and Tenant’s Share of each as
described in Section 4.01 above;

     (b) The amount of Rent Adjustments due Landlord for the last Adjustment Year, less
credit for Rent Adjustment Deposits paid, if any; and

     (c) Any change in the Rent Adjustment Deposit due monthly in the current Adjustment
Year, including the amount or revised amount due for months preceding any such change
pursuant to Landlord’s Statement.

Tenant shall pay to Landlord within ten (10) days after receipt of such statement any amounts for
Rent Adjustments then due in accordance with Landlord’s Statement. Any amounts due from Landlord
to Tenant pursuant to this Section shall be credited to the Rent Adjustment Deposit next coming
due, or refunded to Tenant if the Term has already expired provided Tenant is not in default
hereunder. No interest or penalties shall accrue on any amounts which Landlord is obligated to
credit or refund to Tenant by reason of this Section 4.03. Landlord’s failure to deliver
Landlord’s Statement or to compute the amount of the Rent Adjustments shall not constitute a
waiver by Landlord of its right to deliver such items nor constitute a waiver or release of
Tenant’s obligations to pay such amounts. The Rent Adjustment Deposit shall be credited against
Rent Adjustments due for the applicable Adjustment Year. During the last complete calendar year or
during any partial calendar year in which the Lease terminates, Landlord may include in the Rent
Adjustment Deposit its estimate of Rent Adjustments which may not be finally determined until
after the termination of this Lease. Tenant’s obligation to pay Rent Adjustments survives the
expiration or termination of the Lease. Notwithstanding the foregoing, in no event shall the sum
of Monthly Base Rent and the Rent Adjustments be less than the Monthly Base Rent payable.

4.04 BOOKS AND RECORDS

Landlord shall maintain books and records showing Operating Expenses and Taxes in accordance with
sound accounting and management practices, consistently applied. The Tenant or its representative
(which representative shall be a certified public accountant licensed to do business in the state
in which the Property is located and whose primary business is certified public accounting) shall
have the right, for a period of thirty (30) days following the date upon which Landlord’s
Statement is delivered to Tenant, to examine the Landlord’s books and records with respect to the
items in the foregoing statement of Operating Expenses and Taxes during normal business hours,
upon written notice, delivered at least three (3) business days in advance. If Tenant does not
object in writing to Landlord’s Statement within sixty (60) days of Tenant’s receipt thereof,
specifying the nature of the item in dispute and the reasons therefor, then Landlord’s Statement
shall be considered final and accepted by Tenant. Any amount due to the Landlord as shown on
Landlord’s Statement, whether or not disputed by Tenant as provided herein shall be paid by Tenant
when due as provided above, without prejudice to any such written exception.

4.05 TENANT OR LEASE SPECIFIC TAXES

In addition to Monthly Base Rent, Rent Adjustments, Rent Adjustment Deposits and other charges to
be paid by Tenant, Tenant shall pay to Landlord, upon demand, any and all taxes payable by Landlord
(other than federal or state inheritance, general income, gift or estate taxes) whether or not now
customary or within the contemplation of the parties hereto: (a) upon, allocable to, or measured by
the Rent payable hereunder, including any gross receipts tax or excise tax levied by any
governmental or taxing body with respect to the receipt of such rent; or (b) upon or with respect
to the possession, leasing, operation, management, maintenance, alteration, repair, use or
occupancy by Tenant of the Premises or any portion thereof; or (c) upon the measured value of
Tenant’s personal property or trade fixtures located in the Premises or in any storeroom or any
other place in the Premises or the Property, or the areas used in connection with the operation of
the Property, it being the intention of Landlord and Tenant that, to the extent possible, Tenant
shall cause such taxes on personal property or trade fixtures to be billed to and paid directly by
Tenant; (d) resulting from Landlord Work, Tenant Work or Tenant Alterations to the Premises,
whether title thereto is in Landlord or Tenant; or (e) upon this transaction. Taxes paid by Tenant
pursuant to this Section 4.05 shall not be included in any computation of Taxes as part of
Operating Expenses.

ARTICLE FIVE

SECURITY

     (a) Tenant, at Tenant’s sole cost and expense, concurrently with execution of this Lease,
shall either (1) pay Landlord in cash or immediately available funds or (2) provide Landlord the
Letter of Credit (defined below) as more particularly described below, in each case in the amount
of the Security specified in Section 1.01 as

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security (“Security”) for the full and faithful performance by Tenant of each and every term,
provision, covenant, and condition of this Lease. If Tenant fails timely to perform any of the
terms, provisions, covenants and conditions of this Lease or any other document executed by Tenant
in connection with this Lease, including, but not limited to, the payment of the Monthly Base
Rent, Rent Adjustment Deposits, Rent Adjustments or the repair of damage to the Premises caused by
Tenant (excluding normal wear and tear) then Landlord may use, apply, or retain the whole or any
part of the Security for the payment of any such Monthly Base Rent, Rent Adjustment Deposits or
Rent Adjustments not paid when due, for the cost of repairing such damage, for the cost of
cleaning the Premises, for the payment of any other sum which Landlord may expend or may be
required to expend by reason of Tenant’s failure to perform, and otherwise for compensation of
Landlord for any other loss or damage to Landlord occasioned by Tenant’s failure to perform,
including, but not limited to, any loss of future Rent and any damage or deficiency in the
reletting of the Premises (whether such loss, damages or deficiency accrue before or after summary
proceedings or other reentry by Landlord) and the amount of the unpaid past Rent, future Rent
loss, and all other losses, costs and damages, that Landlord would be entitled to recover if
Landlord were to pursue recovery under California Civil Code Section 1951.2 or 1951.4. If Landlord
so uses, applies or retains all or part of the Security, Tenant shall within five (5) business
days after demand pay or deliver to Landlord in immediately available funds the sum necessary to
replace the amount used, applied or retained, except as specified in (e) below. If Tenant has
fully and faithfully performed and observed all of Tenant’s obligations under the terms,
provisions, covenants and conditions of this Lease, the Security (except any amount retained for
application by Landlord as provided herein) shall be returned or paid over to Tenant no later than
ninety (90) days after the latest of: (i) the Termination Date; (ii) the removal of Tenant from
the Premises; or (iii) the surrender of the Premises by Tenant to Landlord in accordance with this
Lease. Provided, however, in no event shall any such return be construed as an admission by
Landlord that Tenant has performed all of its obligations hereunder.

     (b) The Security, whether in the form of cash, Letter of Credit (defined below) and/or Letter
of Credit Proceeds (defined below), shall not be deemed an advance rent deposit or an advance
payment of any kind, or a measure of Landlord’s damages with respect to Tenant’s failure to
perform, nor shall any action or inaction of Landlord with respect to it or its use or application
be a waiver of, or bar or defense to, enforcement of any right or remedy of Landlord. Landlord
shall not be required to keep the Security separate from its general funds and shall not have any
fiduciary duties or other duties (except as set forth in this Section) concerning the Security.
Tenant shall not be entitled to any interest on the Security. In the event of any sale, lease or
transfer of Landlord’s interest in the Building, Landlord shall have the right to transfer the
Security, or balance thereof, to the vendee, transferee or lessee and any such transfer shall
release Landlord from all liability for the return of the Security. Tenant thereafter shall look
solely to such vendee, transferee or lessee for the return or payment of the Security. Tenant shall
not assign or encumber or attempt to assign or encumber the Security or any interest in it and
Landlord shall not be bound by any such assignment, encumbrance, attempted assignment or attempted
encumbrance, and regardless of one or more assignments of this Lease, Landlord may return the
Security to the original Tenant without liability to any assignee. Tenant hereby waives any and all
rights of Tenant under the provisions of Section 1950.7 of the California Civil Code, and any and
all rights of Tenant under all other provisions of law, now or hereafter enacted, regarding
security deposits.

     (c) If Tenant fails timely to perform any obligation under this Article Five, such breach
shall constitute a Default by Tenant under this Lease without any right to or requirement of any
further notice or cure period under any other Article of this Lease, except such notice and cure
period expressly provided under this Article Five.

     (d) During the first six months after the date on which this Lease has been executed by both
Tenant and Landlord, Tenant shall have the right, at Tenant’s sole cost and expense, to provide
Landlord with the Letter of Credit (defined below) as the Security required under this Lease in
substitution for the cash then held by Landlord as Security. In the event that Tenant first
delivered the Security in the form of cash or immediately available funds prior to delivering the
Letter of Credit, then, within thirty (30) days after Tenant’s delivery to Landlord of the Letter
of Credit, Landlord shall refund to Tenant the amount of cash held by Landlord as Security, less
any amounts thereof used, applied or retained by Landlord pursuant to the provisions of Subsection
(a) and not replenished by Tenant.

     (e) As used herein, “Letter of Credit” shall mean an unconditional, irrevocable sight draft
letter of credit issued, presentable and payable at the San Francisco, California or San Jose,
California office of a major national bank satisfactory to Landlord in its sole discretion (the
“Bank”), naming Landlord as beneficiary, in the amount specified in Section 1.01(14) above. The
Letter of Credit shall provide: (i) that Landlord may make partial and multiple draws thereunder,
up to the face amount thereof, and that Landlord may draw upon the Letter of Credit up to the full
amount thereof, as determined by Landlord, and the Bank will pay to Landlord the amount of such
draw upon receipt by the Bank of a sight draft signed by Landlord without requirement for any
additional documents or statements by Landlord; and (ii) that, in the event of assignment or other
transfer of either Landlord’s interest in this Lease or of any interest in Landlord (including,
without limitation, consolidations, mergers, reorganizations or other entity changes), the Letter
of Credit shall be freely transferable by Landlord, without charge to Landlord and without
recourse, to the assignee or transferee of such interest and the Bank shall confirm the same to
Landlord and such assignee or transferee. The Letter of Credit shall be in the form attached as
Exhibit H hereto. Provided however, if Tenant proposes to use Silicon Valley Bank as the
issuer of the Letter of Credit, the form of Letter of Credit set forth in Exhibit E hereto
will be acceptable to Landlord. Landlord may (but shall not be required to) draw upon the Letter of
Credit and use the proceeds therefrom (the “Letter of Credit Proceeds”) or any portion thereof in
any manner Landlord is permitted to use the Security under this Article Five. In the event
Landlord draws upon the Letter of Credit and elects not to terminate the Lease, but to use the
Letter of Credit Proceeds, then within five (5) business days after Landlord gives Tenant written
notice specifying the amount of the Letter of Credit Proceeds so utilized by Landlord, Tenant shall
deliver to Landlord an amendment to the Letter of Credit or a replacement Letter of Credit in an
amount equal to one hundred percent (100%) of the then-required amount of the Letter of Credit.
Tenant’s failure to deliver such amendment or replacement of the Letter of Credit to Landlord
within five (5) business days after Landlord’s notice shall constitute a Default by Tenant under
this Lease. The Letter of Credit shall have an initial term of no longer than one (1) year, shall
be “evergreen”, and shall be extended, reissued or replaced by Tenant, in each case at least thirty
(30) days prior to its expiration in a manner that fully complies with the requirements of this
Article Five, so that in all events the Letter of Credit required hereunder shall be in full force

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and effect continuously until the date (the “L/C Expiration Date”) for return of the Security
described in Subsection (a) above. No more often than once per year, Landlord shall have the right
to require Tenant to deliver to Landlord, on 15 days prior notice, a replacement Letter of Credit
on the same terms and conditions set forth in this Article Five, in the event that Landlord
determines, in its good faith judgment, that the issuing Bank is no longer satisfactory to remain
as the issuer of the Letter of Credit. Any advice from the issuer that it intends to withdraw or
not extend the Letter of Credit prior to any scheduled annual expiration or the L/C Expiration Date
shall entitle the Landlord to immediately draw upon the Letter of Credit.

ARTICLE SIX

UTILITIES & SERVICES

6.01 LANDLORD’S GENERAL SERVICES

Landlord shall provide maintenance and services as provided in Article Eight.

6.02 TENANT TO OBTAIN & PAY DIRECTLY

     (a) Tenant shall be responsible for and shall pay promptly all charges for gas, electricity,
sewer, heat, light, power, telephone, refuse pickup (to be performed on a regularly scheduled basis
so that accumulated refuse does not exceed the capacity of Tenant’s refuse bins), janitorial
service and all other utilities, materials and services furnished directly to or used by Tenant in,
on or about the Premises, together with all taxes thereon. Tenant shall contract directly with the
providing companies for such utilities and services.

     (b) Notwithstanding any provision of the Lease to the contrary, without, in each instance, the
prior written consent of Landlord, as more particularly provided in Article Nine, Tenant shall not:
(i) make any alterations or additions to the electric or gas equipment or systems or other Building
systems. Tenant’s use of electric current shall at no time exceed the capacity of the wiring,
feeders and risers providing electric current to the Premises or the Building. The consent of
Landlord to the installation of electric equipment shall not relieve Tenant from the obligation to
limit usage of electricity to no more than such capacity.

6.03 TELEPHONE SERVICES

All telegraph, telephone, and communication connections which Tenant may desire outside the
Premises shall be subject to Landlord’s prior written approval, in Landlord’s sole discretion, and
the location of all wires and the work in connection therewith shall be performed by contractors
approved by Landlord and shall be subject to the direction of Landlord, except that such approval
is not required as to Tenant’s cabling from the Premises in a route designated by Landlord to any
telephone cabinet or panel provided for Tenant’s connection to the telephone cable serving the
Building, so long as Tenant’s equipment does not require connections different than or additional
to those to the telephone cabinet or panel provided. As to any such connections or work outside
the Premises requiring Landlord’s approval, Landlord reserves the right reasonably to approve the
entity or entities providing telephone or other communication cable installation, removal, repair
and maintenance outside the Premises and reasonably to restrict and control access to telephone
cabinets or panels outside the Premises. Tenant shall be responsible for and shall pay all costs
incurred in connection with the installation of telephone cables and communication wiring in the
Premises, including any hook-up, access and maintenance fees related to the installation of such
wires and cables in the Premises and the commencement of service therein, and the maintenance
thereafter of such wire and cables; and there shall be included in Operating Expenses for the
Building all installation, removal, hook-up or maintenance costs incurred by Landlord in
connection with telephone cables and communication wiring serving the Building which are not
allocable to any individual users of such service but are allocable to the Building generally. If
Tenant fails to maintain all telephone cables and communication wiring in the Premises and such
failure affects or interferes with the operation or maintenance of any other telephone cables or
communication wiring serving the Building, Landlord or any vendor hired by Landlord may enter into
and upon the Premises forthwith and perform such repairs, restorations or alterations as Landlord
deems necessary in order to eliminate any such interference (and Landlord may recover from Tenant
all of Landlord’s costs in connection therewith). No later than the Termination Date, Tenant
agrees to remove all telephone cables and communication wiring installed by Tenant for and during
Tenant’s occupancy, which Landlord shall request Tenant to remove. Tenant agrees that neither
Landlord nor any of its agents or employees shall be liable to Tenant, or any of Tenant’s
employees, agents, customers or invitees or anyone claiming through, by or under Tenant, for any
damages, injuries, losses, expenses, claims or causes of action because of any interruption,
diminution, delay or discontinuance at any time for any reason in the furnishing of any telephone
or other communication service to the Premises and the Building.

6.04 FAILURE OR INTERRUPTION OF UTILITY OR SERVICE

To the extent that any equipment or machinery furnished or maintained by Landlord outside the
Premises is used in the delivery of utilities directly obtained by Tenant pursuant to Section 6.02
and breaks down or ceases to function properly, Landlord shall use reasonable diligence to repair
same promptly. In the event of any failure, stoppage or interruption of, or change in, any
utilities or services supplied by Landlord which are not directly obtained by Tenant, Landlord
shall use reasonable diligence to have service promptly resumed. In either event covered by the
preceding two sentences, if the cause of any such failure, stoppage or interruption of, or change
in, utilities or services is within the control of a public utility, other public or quasi-public
entity, or utility provider outside Landlord’s control, notification to such utility or entity of
such failure, stoppage or interruption and request to remedy the same shall constitute “reasonable
diligence” by Landlord to have service promptly resumed. Notwithstanding any other provision of
this Section to the contrary, in the event of any failure, stoppage or interruption of, or change
in, any utility or other service furnished to the Premises or the Project resulting from any cause
other than the gross negligence or willful and wrongful act of Landlord or its agents or
contractors, including changes in service provider or Landlord’s compliance with any voluntary or
similar governmental or business guidelines now or hereafter published or any requirements now or
hereafter established by any governmental agency, board or bureau having

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jurisdiction over the operation of the Property: (a) Landlord shall not be liable for, and Tenant
shall not be entitled to, any abatement or reduction of Rent; (b) no such failure, stoppage, or
interruption of any such utility or service shall constitute an eviction of Tenant or relieve
Tenant of the obligation to perform any covenant or agreement of this Lease to be performed by
Tenant; (c) Landlord shall not be in breach of this Lease nor be liable to Tenant for damages or
otherwise.

6.05 INTENTIONALLY OMITTED

6.06 SIGNAGE

Except as set forth in Rider 2, Tenant shall not install any signage within the Project,
the Building or the Premises without obtaining the prior written approval of Landlord, and Tenant
shall be responsible for procurement, installation, maintenance and removal of any such signage
installed by Tenant, and all costs in connection therewith. Any such signage shall comply with
Landlord’s current Project signage criteria and all Laws.

ARTICLE SEVEN

POSSESSION, USE AND CONDITION OF PREMISES

7.01 POSSESSION AND USE OF PREMISES

     (a) Tenant shall occupy and use the Premises only for the uses specified in Section 1.01(17)
to conduct Tenant’s business. Tenant shall not occupy or use the Premises (or permit the use or
occupancy of the Premises) for any purpose or in any manner which: (1) is unlawful or in violation
of any Law or Environmental Law; (2) may be dangerous to persons or property or which may increase
the cost of, or invalidate, any policy of insurance carried on the Building or covering its
operations; (3) is contrary to or prohibited by the terms and conditions of this Lease or the rules
and regulations as provided in Article Eighteen; (4) contrary to or prohibited by the articles,
bylaws or rules of any owner’s association affecting the Project; (5) would obstruct or interfere
with the rights of other tenants or occupants of the Building or the Project, or injure or annoy
them, or would tend to create or continue a nuisance; or (6) would constitute any waste in or upon
the Premises or Project.

     (b) Landlord and Tenant acknowledge that the Americans With Disabilities Act of 1990 (42
U.S.C. §12101 et seq.) and regulations and guidelines promulgated thereunder, as all of the same
may be amended and supplemented from time to time (collectively
referred to herein as the “ADA”)
establish requirements for business operations, accessibility and barrier removal, and that such
requirements may or may not apply to the Premises, the Building and the Project depending on, among
other things: (1) whether Tenant’s business is deemed a “public accommodation” or “commercial
facility”, (2) whether such requirements are “readily achievable”, and (3) whether a given
alteration affects a “primary function area” or triggers “path of travel” requirements. The
parties hereby agree that: (a) Landlord shall be responsible for ADA Title III compliance in the
Common Areas, except as provided below, (b) Tenant shall be responsible for ADA Title III
compliance in the Premises, including any leasehold improvements or other work to be performed in
the Premises under or in connection with this Lease, (c) Landlord may perform, or require that
Tenant perform, and Tenant shall be responsible for the cost of, ADA
Title III “path of travel”
requirements triggered by Tenant Additions in the Premises, and (d) Landlord may perform, or
require Tenant to perform, and Tenant shall be responsible for the cost of, ADA Title III
compliance in the Common Areas necessitated by the Building being deemed to be a “public
accommodation” instead of a “commercial facility” as a result of Tenant’s use of the Premises.
Tenant shall be solely responsible for requirements under Title I of the ADA relating to Tenant’s
employees.

     (c) Landlord and Tenant agree to cooperate and use commercially reasonable efforts to
participate in traffic management programs generally applicable to businesses located in or about
the area and Tenant shall encourage and support van and car pooling by, and staggered and flexible
working hours for, its office workers and service employees to the extent reasonably permitted by
the requirements of Tenant’s business. Neither this Section or any other provision of this Lease
is intended to or shall create any rights or benefits in any other person, firm, company,
governmental entity or the public.

     (d) Tenant agrees to cooperate with Landlord and to comply with any and all guidelines or
controls concerning energy management imposed upon Landlord by federal or state governmental
organizations or by any energy conservation association to which Landlord is a party or which is
applicable to the Building.

7.02 HAZARDOUS MATERIAL

     (a) Tenant shall not use, generate, manufacture, produce, store, handle, release, discharge,
or dispose of, on, under or about the Premises or any part of the Project, or transport to or from
the Premises or any part of the Project, any Hazardous Material, or allow its employees, agents,
contractors, licensees, invitees or any other person or entity under Tenant’s control (“Tenant
Parties”) to do so except to the extent expressly provided below. Provided that the Premises are
used only for the uses specified in Section 1.01(17) above, Tenant shall be permitted to use and
store in, and transport to and from, the Premises Hazardous Material
identified on Exhibit D hereto and by this reference incorporated herein (“Permitted Hazardous Material”) so long
as: (i) each item of the Permitted Hazardous Material is used or stored in, or transported to and
from, the Premises only to the extent necessary for Tenant’s operation of its business at the
Premises; (ii) at no time shall any Permitted Hazardous Material be in use or storage at the
Premises in excess of the quantity specified therefor in
Exhibit D; (iii) Tenant shall not
install any underground tanks of any type; and (iv) the conditions and provisions set forth in
this Section 7.02 are complied with. If Tenant desires to add additional types or quantities of
Hazardous Materials to the list of Permitted Hazardous Materials
specified in Exhibit D.
Tenant shall give Landlord notice of the Hazardous Materials and quantities thereof that Tenant
desires to use at the Premises and Landlord shall thereafter have the right to approve or
disapprove such additional Hazardous Materials in Landlord’s sole discretion within ten (10) days
after receipt of such notice. Failure to notify Tenant in writing of its decision within said ten
(10) day period shall be deemed disapproval by Landlord. Tenant shall comply with

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and shall cause all Tenant Parties to comply with all Environmental Laws and other Laws pertaining
to Tenant’s occupancy and use of the Premises and concerning the proper use, generation,
manufacture, production, storage, handling, release, discharge, removal and disposal of any
Hazardous Material introduced to the Premises, the Building or the Property by Tenant or any of
the Tenant Parties. Without limiting the generality of the foregoing:

(1) Tenant shall provide Landlord promptly with copies of: (x) all permits, licenses and
other governmental and regulatory approvals with respect to the use, generation,
manufacture, production, storage, handling, release, discharge, removal and disposal by
Tenant or any of the Tenant Parties of Hazardous Material at the Project; and (y) each
hazardous material management plan or similar document (“Plan(s)”) with respect to use,
generation, manufacture, production, storage, handling, release, discharge, removal or
disposal of Hazardous Material by Tenant or any of the Tenant Parties necessary to comply
with Environmental Laws or other Laws prepared by or on behalf of Tenant or any of the
Tenant Parties (whether or not required to be submitted to a governmental agency) and
updates thereof in the event of any change in the Permitted Hazardous Materials used by
Tenant or when otherwise required by Law.

(2) If Tenant is notified of any investigation or violation of any Environmental Laws or
other Laws arising from any activity of Tenant or any of the Tenant Parties at the Property,
or if Tenant knows, or has reasonable cause to believe, that a Hazardous Material has come
to be located in, on, under or about the Premises or the Project, other than as previously
consented to by Landlord, Tenant shall immediately give written notice of such fact to
Landlord, and provide Landlord with a copy of all reports, notices, claims or other
documentation which it has concerning the presence of such Hazardous Material. In such
event Landlord may conduct, at Tenant’s expense, such tests and studies as Landlord deems
desirable relating to compliance by Tenant or any of the Tenant Parties with this Lease,
Environmental Laws, other Laws, or relating to the alleged presence of Hazardous Material
introduced to the Premises, the Building or the Property by Tenant or any of the Tenant
Parties. Further, Landlord may conduct, at Landlord’s expense, such tests and studies as
Landlord deems desirable relating to compliance by Tenant or any of the Tenant Parties with
this Lease, Environmental Laws, other Laws, or relating to the alleged presence of Hazardous
Material introduced to the Premises, the Building or the Property by Tenant or any of the
Tenant Parties. In the event such tests and studies done at Landlord’s expense reasonably
indicate that Tenant or Tenant Parties have violated Environmental Laws or caused a release
of Hazardous Material, then Tenant shall reimburse Landlord the cost of such tests and
studies.

(3) Neither Tenant nor any of the Tenant Parties shall cause or permit any Hazardous
Material to be released, discharged or disposed of in, on, under, or about the Premises or
the Project (including through the plumbing or sanitary sewer system) and shall promptly, at
Tenant’s expense, take all investigatory and/or remedial action reasonably recommended,
whether or not formally ordered or required, for the cleanup of any contamination of, and
for the maintenance, security and/or monitoring of the Premises, the Project or neighboring
properties, that was caused or materially contributed to by Tenant, or pertaining to or
involving any Hazardous Material brought onto the Premises or the Project by Tenant or any
of the Tenant Parties.

(4) Tenant shall, no later than the Termination Date, surrender the Premises to Landlord
free of Hazardous Material and with all remedial and/or closure plans completed (and deliver
evidence thereof to Landlord).

     (b) To the extent permitted by law, Tenant hereby indemnifies and agrees to protect, defend
and hold the Indemnitees harmless against all actions, claims, demands, liability, costs and
expenses, including reasonable attorneys’ fees and expenses for the defense thereof, arising from
the use, generation, manufacture, production, storage, handling, release, threatened release,
discharge, disposal, transportation to or from, or presence of any Hazardous Material on, under or
about the Premises or any part of the Project caused by Tenant or by any of the Tenant Parties,
whether before, during or after the Term. Tenant’s obligations under this Section 7.02 shall
survive the expiration or earlier termination of this Lease. In case of any action or proceeding
brought against the Indemnitees by reason of any such claim, upon notice from Landlord, Tenant
covenants to defend such action or proceeding by counsel chosen by Landlord, in Landlord’s sole
discretion. Landlord reserves the right to settle, compromise or dispose of any and all actions,
claims and demands related to the foregoing indemnity, subject to the prior written approval of
Tenant, which may not unreasonably be withheld. Landlord acknowledges that the sewer system for
the Premises joins a common sewer discharge line shared by other tenants of the Building and
confirms that notwithstanding that some elements of the Building sewer discharge line are shared,
Tenant shall be responsible only for materials actually discharged by Tenant or the Tenant Parties.

     (c) The right to use and store in, and transport to and from, the Premises the Permitted
Hazardous Material is personal to Genomic Health and may not be assigned or otherwise transferred
by it without the prior written consent of Landlord, which consent may be withheld in Landlord’s
sole discretion, except (i) to a Permitted Transferee which is an assignee of the Lease and which
has satisfied the requirements of Sections 10.01 and 10.05 of this Lease; and (ii) Genomic Health
may permit a Permitted Transferee which is a sublessee to use and store in, and transport to and
from, the Premises the Permitted Hazardous Material to the same extent as Genomic Health has such
right under this Lease, subject to all the provisions of this Lease. Any consent by Landlord
pursuant to Article Ten to an assignment, transfer, subletting, mortgage, pledge, hypothecation or
encumbrance of this Lease, and any interest therein or right or privilege appurtenant thereto,
shall not constitute consent by Landlord to the use or storage at, or transportation to, the
Premises of any Hazardous Material (including a Permitted Hazardous Material) by any such assignee,
sublessee or transferee unless Landlord expressly agrees otherwise in writing. Provided however, at
the time Tenant requests approval of any proposed assignment or sublease of this Lease by Tenant,
Tenant shall submit to Landlord the proposed Permitted Hazardous Material list of the proposed
assignee or sublessee. Landlord shall have the right, in its sole discretion, to approve the
proposed assignee’s or sublessee’s proposed Permitted Hazardous Material list, or to require
modifications to said list. In the event that Landlord does not approve of the proposed assignee’s
or sublessee’s Permitted Hazardous Material list, or the proposed assignee or sublessee cannot or
will not modify said list, then it shall be reasonable for purposes of Article Ten hereof for

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Landlord to refuse its consent to the proposed assignee or sublessee. In the event that the
proposed Hazardous Material list of the assignee or sublessee includes any Hazardous Material
different from or in greater quantity than those on Tenant’s Permitted Hazardous Material list,
Tenant shall pay Landlord, whether or not Landlord consents to the proposed list of Permitted
Hazardous Materials and/or to the proposed assignment or sublease, (i) a processing fee of Three
Thousand Dollars ($3,000.00) at the time Tenant submits the request for approval, and (ii) the
reasonable fees and expenses of any consultants retained by Landlord in connection with review of
the proposed Permitted Hazardous Material list and use thereof by the proposed assignee or
sublessee. Any consent by Landlord to the use or storage at, or transportation to or from the
Premises, of any Hazardous Material (including a Permitted Hazardous Material) by an assignee,
sublessee or transferee of Tenant shall not constitute a waiver of Landlord’s right to refuse such
consent as to any subsequent assignee or transferee.

     (d) Tenant acknowledges that the sewer piping at the Project is made of ABS plastic.
Accordingly, without Landlord’s prior written consent, which may be given or withheld in Landlord’s
sole discretion, only ordinary domestic sewage is permitted to be put into the drains at the
Premises. UNDER NO CIRCUMSTANCES SHALL Tenant EVER DEPOSIT ANY ESTERS OR KETONES (USUALLY FOUND IN
SOLVENTS TO CLEAN UP PETROLEUM PRODUCTS) IN THE DRAINS AT THE PREMISES. If Tenant desires to put
any substances other than ordinary domestic sewage into the drains, it shall first submit to
Landlord a complete description of each such substance, including its chemical composition, and a
sample of such substance suitable for laboratory testing. Landlord shall promptly determine whether
or not the substance can be deposited into the drains and its determination shall be absolutely
binding on Tenant. Upon demand, Tenant shall reimburse Landlord for expenses incurred by Landlord
in making such determination. If any substances not so approved hereunder are deposited in the
drains in Tenant’s Premises, Tenant shall be liable to Landlord for all damages resulting
therefrom, including but not limited to all costs and expenses incurred by Landlord in repairing or
replacing the piping so damaged.

7.03 LANDLORD ACCESS TO PREMISES; APPROVALS

     (a) Tenant shall permit Landlord to erect, use and maintain pipes, ducts, wiring and conduits
in and through the Premises, so long as Tenant’s use, layout or design of the Premises is not
materially affected or altered. Landlord or Landlord’s agents shall have the right to enter upon
the Premises (i) in the event of an emergency, without prior notice, or (ii) with 24-hour prior
notice to inspect the Premises, to perform janitorial and other services (if any), to conduct
safety and other testing in the Premises and to make such repairs, alterations, improvements or
additions to the Premises or the Building or other parts of the Property as Landlord may deem
necessary or desirable (including all alterations, improvements and additions in connection with a
change in service provider or providers). Janitorial and cleaning services (if any) shall be
performed after normal business hours. Any entry or work by Landlord may be during normal business
hours and Landlord may use reasonable efforts to ensure that any entry or work shall not materially
interfere with Tenant’s occupancy of the Premises.

     (b) If Tenant or its agents shall not be personally present to permit an entry into the
Premises when for any reason an entry therein shall be necessary or permissible, Landlord (or
Landlord’s agents), after having properly notified Tenant (unless Landlord believes an emergency
situation exists), may enter the Premises without rendering Landlord or its agents liable therefor,
and without relieving Tenant of any obligations under this Lease.

     (c) Landlord may enter the Premises for the purpose of conducting such inspections, tests and
studies as Landlord may deem desirable or necessary to confirm Tenant’s compliance with all Laws
and Environmental Laws or for other purposes necessary in Landlord’s reasonable judgment to ensure
the sound condition of the Property and the systems serving the Property. Landlord’s rights under
this Section 7.03 (c) are for Landlord’s own protection only, and Landlord has not, and shall not
be deemed to have assumed, any responsibility to Tenant or any other party as a result of the
exercise or non-exercise of such rights, for compliance with Laws or Environmental Laws or for the
accuracy or sufficiency of any item or the quality or suitability of any item for its intended use.

     (d) Landlord may do any of the foregoing, or undertake any of the inspection or work described
in the preceding paragraphs without such action constituting an actual or constructive eviction of
Tenant, in whole or in part, or giving rise to an abatement of Rent by reason of loss or
interruption of business of the Tenant, or otherwise.

     (e) The review, approval or consent of Landlord with respect to any item required or permitted
under this Lease is for Landlord’s own protection only, and Landlord has not, and shall not be
deemed to have assumed, any responsibility to Tenant or any other party, as a result of the
exercise or non-exercise of such rights, for compliance with Laws or Environmental Laws or for the
accuracy or sufficiency of any item or the quality or suitability of any item for its intended use.

7.04 QUIET ENJOYMENT

Landlord covenants, in lieu of any implied covenant of quiet possession or quiet enjoyment, that
so long as Tenant is in compliance with the covenants and conditions set forth in this Lease,
Tenant shall have the right to quiet enjoyment of the Premises without hindrance or interference
from Landlord or those claiming through Landlord, and subject to the covenants and conditions set
forth in the Lease and to the rights of any Mortgagee or ground lessor.

ARTICLE EIGHT

MAINTENANCE & HVAC

8.01 LANDLORD’S MAINTENANCE

Subject to Article Fourteen and Section 8.02, Landlord shall maintain the structural portions of
the Building, the roof, exterior walls and exterior doors, foundation, and underslab standard
sewer system of the Building in good, clean

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and safe condition. Notwithstanding the foregoing, Landlord shall have no responsibility to
perform preventive maintenance or service for, or to repair any heating, ventilation and air
conditioning equipment and systems serving the Premises (“HVAC”), and all such preventive
maintenance, service, and repairs shall be performed by Tenant pursuant to the terms of Section
8.02. Landlord shall also (a) maintain the landscaping, parking facilities and other Common
Areas of the Project, and (b) wash the outside of exterior windows at intervals determined by
Landlord. Except as provided in Article Fourteen and Article Fifteen, there shall be no
abatement of rent, no allowance to Tenant for diminution of rental value and no liability of
Landlord by reason of inconvenience, annoyance or any injury to or interference with Tenant’s
business arising from the making of or the failure to make any repairs, alterations or
improvements in or to any portion of the Project or in or to any fixtures, appurtenances or
equipment therein. Tenant waives the right to make repairs at Landlord’s expense under any law,
statute or ordinance now or hereafter in effect.

8.02 TENANT’S MAINTENANCE

     (a) Subject to the provisions of Article Fourteen, Tenant shall, at Tenant’s sole cost and
expense, maintain and make all repairs to the Premises and fixtures therein which Landlord is not
required to make pursuant to Section 8.01, including repairs to the interior walls, ceilings and
windows of the Premises, the interior doors, Tenant’s signage, and the electrical, life-safety,
plumbing located within the Premises and any HVAC serving only the Premises, and shall maintain
the Premises, the fixtures, HVAC systems serving only the Premises, utilities systems or portions
thereof serving only the Premises, and garbage enclosures, if any, for Tenant’s exclusive use
outside the Premises, in a good, clean and safe condition. Tenant shall deliver to Landlord a
copy of any maintenance contract entered into by Tenant with respect to the Premises. Tenant
shall also, at Tenant’s expense, keep any non-standard heating, ventilating and air conditioning
equipment and other non-standard equipment installed by or on behalf of Tenant in good condition
and repair, using contractors approved in advance, in writing, by Landlord, which approval shall
not be unreasonably withheld. Notwithstanding Section 8.01 above, to the extent that Landlord is
not reimbursed by insurance and no waiver set forth in Section 16.04 is applicable, Tenant will
pay for any repairs to the Building or the Project which are caused by any negligence or willful
and wrongful act, of Tenant or its assignees, subtenants or employees, or of the respective
agents of any of the foregoing persons, or of any other persons permitted in the Building or
elsewhere in the Project by Tenant or any of them. Tenant will maintain the Premises, and will
leave the Premises upon termination of this Lease, in a safe, clean, neat and sanitary condition.

     (b) With respect to HVAC, Tenant, at Tenant’s sole cost and expense, shall enter into
contracts (“HVAC Service Contracts”) for regularly scheduled inspections and preventive
maintenance and service, as to which the contractors, scope of work, frequency of inspection,
maintenance or service, shall be subject to Landlord’s prior written approval, in its sole
discretion. Tenant shall cause the contractor for such HVAC Service
Contracts to deliver written reports to Landlord within ten (10) days after the date of such
inspection, maintenance and/or service. Tenant shall deliver to Landlord a copy of the initial
HVAC Service Contracts within sixty (60) days after the Commencement Date and of subsequent
HVAC Service Contracts entered into by Tenant within ten (10) days after execution thereof
(which subsequent HVAC Service Contracts shall be subject to the same approval standards and
requirements as set forth above with respect to the initial contract). In the event Tenant
fails, in the reasonable judgment of Landlord, to meet the requirements for such HVAC Service
Contracts and cause such inspections, maintenance and service to be performed, which failure
continues at the end of fifteen (15) days following written notice given by Landlord stating
the nature of the failure, Landlord shall have the right (but shall not be obligated) to
obtain such HVAC Service Contracts and to enter the Premises and perform such inspection,
maintenance and service, at Tenant’s sole cost and expense; provided, however, if the nature
of the maintenance or repair is such that it cannot, with the exercise of reasonable
diligence, be completed within fifteen (15) days of Tenant’s receipt of Landlord’s notice,
Landlord shall not undertake such inspection, maintenance and service at Tenant’s expense
provided Tenant commences such inspection, maintenance and service in the manner required
above within said 15-day period and thereafter diligently and continuously prosecutes the same
to completion and provided further, however, that in the event of an emergency condition,
Landlord shall have the right to make such inspection, maintenance, service and/or repairs on
behalf of Tenant at Tenant’s sole cost and expense after giving Tenant such notice, if any, as
is reasonable under the circumstances. Landlord’s right of entry pursuant to Section
7.03 shall include the right to enter and inspect the Premises for violations of Tenant’s
covenants herein. Tenant shall maintain written records of HVAC inspection, maintenance, service
repairs, and shall use certified technicians approved in writing by Landlord to perform such
maintenance and repairs.

ARTICLE NINE

ALTERATIONS AND IMPROVEMENTS

9.01 TENANT ALTERATIONS

     (a) The following provisions shall apply to the completion of any Tenant
Alterations:

     (1) Tenant shall not, except as provided herein, without the prior written consent of
Landlord, which consent shall not be unreasonably withheld, make or cause to be made any
Tenant Alterations in or to the Premises or any Property systems serving the Premises.
Prior to making any Tenant Alterations, Tenant shall give Landlord ten (10) days prior
written notice (or such earlier notice as would be necessary pursuant to applicable Law)
to permit Landlord sufficient time to post appropriate notices of non-responsibility. Subject to all other requirements of this Article Nine, Tenant may,
without Landlord’s prior written consent, undertake (i) Decoration work and/or (ii) any
Alterations that (x) do not adversely affect the roof, structural portions or the systems
or equipment of the Building, (y) are not visible from the exterior of the Building, and
(z) do not cost, in the aggregate, over the Term of the Lease, in excess of $50,000.
Tenant shall furnish Landlord with the names and addresses of all contractors and
subcontractors and copies of all contracts. All Tenant Alterations shall be completed at
such time and in such manner as Landlord may from time to time designate, and only by
contractors or mechanics approved by Landlord, which approval shall not be unreasonably
withheld. The contractors, mechanics and engineers who may be used are further limited to
those whose work will not cause or threaten to cause disharmony or interference with
Landlord or other tenants in the Building and their respective agents and contractors

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performing work in or about the Building. Landlord may further condition its consent upon
Tenant furnishing to Landlord and Landlord approving prior to the commencement of any work
or delivery of materials to the Premises related to the Tenant Alterations such of the
following as specified by Landlord: architectural plans and specifications, opinions from
Landlord’s engineers stating that the Tenant Alterations will not in any way adversely
affect the Building’s systems, necessary permits and licenses, certificates of insurance,
and such other documents in such form reasonably requested by Landlord. Landlord may, in the
exercise of reasonable judgment, request that Tenant provide Landlord with appropriate
evidence of Tenant’s ability to complete and pay for the completion of the Tenant
Alterations such as a performance bond or letter of credit. Upon completion of the Tenant
Alterations, Tenant shall deliver to Landlord an as-built mylar and digitized (if available)
set of plans and specifications for the Tenant Alterations.

     (2) Tenant shall pay the cost of all Tenant Alterations and the cost of decorating the
Premises and any work to the Property occasioned thereby. In connection with completion
of any Tenant Alterations, Tenant shall, upon receipt of Landlord’s itemized invoice
therefor, pay Landlord’s actual and reasonable costs to review the plans and specifications
for such Tenant Alterations and to monitor the performance thereof, including a construction
administration fee and all elevator and hoisting charges at Landlord’s then standard rate.
Upon completion of Tenant Alterations, Tenant shall furnish Landlord with contractors’
affidavits and full and final waivers of lien and receipted bills
covering all labor and
materials expended and used in connection therewith and such other documentation reasonably
requested by Landlord or Mortgagee.

     (3) Tenant agrees to complete all Tenant Alterations (i) in accordance with all Laws,
Environmental Laws, all requirements of applicable insurance companies and in accordance
with Landlord’s standard construction rules and regulations, and (ii) in a good and
workmanlike manner with the use of good grades of materials. Tenant shall notify Landlord
immediately if Tenant receives any notice of violation of any Law in connection with
completion of any Tenant Alterations and shall immediately take such steps as are necessary
to remedy such violation. In no event shall such supervision or right to supervise by
Landlord nor shall any approvals given by Landlord under this Lease constitute any warranty
by Landlord to Tenant of the adequacy of the design, workmanship or quality of such work or
materials for Tenant’s intended use or of compliance with the requirements of Section
9.01(a)(3)(i) and (ii) above or impose any liability upon Landlord in connection with the
performance of such work.

     (b) All Tenant Additions to the Premises whether installed by Landlord or Tenant, shall
without compensation or credit to Tenant, become part of the Premises and the property of Landlord
at the time of their installation and shall remain in the Premises, unless pursuant to Article
Twelve, Tenant may remove them or is required to remove them at Landlord’s request. Tenant’s
Personal Property, as set forth in Exhibit G, shall at all times remain the property of
Tenant and Tenant shall remove such property at the expiration or earlier termination of this
Lease.

9.02 LIENS

Tenant shall not permit any lien or claim for lien of any mechanic, laborer or supplier or any
other lien to be filed against the Building, the Land, the Premises, or any other part of the
Property arising out of work performed, or alleged to have been performed by, or at the direction
of, or on behalf of Tenant. If any such lien or claim for lien is filed, Tenant shall within ten
(10) days of receiving notice of such lien or claim (a) have such lien or claim for lien released
of record or (b) deliver to Landlord a bond in form, content, amount, and issued by surety,
satisfactory to Landlord, indemnifying, protecting, defending and holding harmless the Indemnitees
against all costs and liabilities resulting from such lien or claim for lien and the foreclosure
or attempted foreclosure thereof. If Tenant fails to take any of the above actions, Landlord, in
addition to its rights and remedies under Article Eleven, without investigating the validity of
such lien or claim for lien, may pay or discharge the same and Tenant shall, as payment of
additional Rent hereunder, reimburse Landlord upon demand for the amount so paid by Landlord,
including Landlord’s expenses and reasonable attorneys’ fees.

ARTICLE TEN

ASSIGNMENT AND SUBLETTING

10.01 ASSIGNMENT AND SUBLETTING

     (a) Without the prior written consent of Landlord, which may be withheld in Landlord’s sole
discretion, Tenant may not sublease, assign, mortgage, pledge, hypothecate or otherwise transfer
or permit the transfer of this Lease or the encumbering of Tenant’s interest therein in whole or
in part, by operation of Law or otherwise or permit the use or occupancy of the Premises, or any
part thereof, by anyone other than Tenant, provided, however, if Landlord chooses not to recapture
the space proposed to be subleased or assigned as provided in Section 10.02, Landlord shall not
unreasonably withhold its consent to a subletting or assignment under this Section 10.01. Tenant
agrees that the provisions governing sublease and assignment set forth in this Article Ten shall
be deemed to be reasonable. If Tenant desires to enter into any sublease of the Premises or
assignment of
this Lease, Tenant shall deliver written notice thereof to Landlord (“Tenant’s Notice”),
together with the identity of the proposed subtenant or assignee and the proposed principal terms
thereof and financial and other information sufficient for Landlord to make an informed judgment
with respect to such proposed subtenant or assignee at least sixty (60) days prior to the
commencement date of the term of the proposed sublease or assignment. If Tenant proposes to
sublease less than all of the Rentable Area of the Premises, the space proposed to be sublet and
the space retained by Tenant must each be a marketable unit as reasonably determined by Landlord
and otherwise in compliance with all Laws; provided however, so long as the Tenant is Genomic
Health or a Permitted Transferee which is an assignee of the Lease which has satisfied the
requirements of Sections 10.01 and 10.05 below, the foregoing shall not apply to a sublease for a
sublease term of a year or less, for undemised space in the aggregate (for one or more such
subleases in effect at any one time) up to 3,000 square feet of Rentable Area. Landlord shall

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notify Tenant in writing of its approval or disapproval of the proposed sublease or assignment or
its decision to exercise its rights under Section 10.02 within thirty (30) days after receipt of
Tenant’s Notice (and all required information). In no event may Tenant sublease any portion of the
Premises or assign the Lease to any other tenant of the Project. Tenant shall submit for
Landlord’s approval (which approval shall not be unreasonably withheld) any advertising which
Tenant or its agents intend to use with respect to the space proposed to be sublet.

     (b) With respect to Landlord’s consent to an assignment or sublease, Landlord may take into
consideration any factors which Landlord may deem relevant, and the reasons for which Landlord’s
denial shall be deemed to be reasonable shall include, without limitation, the following:

(i) the business reputation or creditworthiness of any proposed subtenant or
assignee is not acceptable to Landlord; or

(ii) in Landlord’s reasonable judgment the proposed assignee or subtenant would
diminish the value or reputation of the Building or Landlord; or

(iii) any proposed assignee’s or subtenant’s use of the Premises would violate
Section 7.01 of the Lease or would violate the provisions of any other leases of tenants in
the Project;

(iv) the proposed assignee or subtenant is either a governmental agency, a school or
similar operation, or a medical related practice; or

(v) the proposed subtenant or assignee is a bona fide prospective tenant of Landlord
in the Project as demonstrated by a written proposal dated within ninety (90) days prior to
the date of Tenant’s request; or

(vi) the proposed subtenant or assignee would materially increase the estimated
pedestrian and vehicular traffic to and from the Premises and the Building.

In no event shall Landlord be obligated to consider a consent to any proposed assignment of the
Lease which would assign less than the entire Premises. In the event Landlord wrongfully withholds
its consent to any proposed sublease of the Premises or assignment of the Lease, Tenant’s sole and
exclusive remedy therefor shall be to seek specific performance of Landlord’s obligations to
consent to such sublease or assignment.

     (c) Any sublease or assignment shall be expressly subject to the terms and conditions of this
Lease. Any subtenant or assignee shall execute such documents as Landlord may reasonably require to
evidence such subtenant or assignee’s assumption of the obligations and liabilities of Tenant under
this Lease. Tenant shall deliver to Landlord a copy of all agreements executed by Tenant and the
proposed subtenant and assignee with respect to the Premises. Landlord’s approval of a sublease,
assignment, hypothecation, transfer or third party use or occupancy shall not constitute a waiver
of Tenant’s obligation to obtain Landlord’s consent to further assignments or subleases,
hypothecations, transfers or third party use or occupancy.

     (d) For purposes of this Article Ten, an assignment shall be deemed to include a change in the
majority control of Tenant, resulting from any transfer, sale or assignment of shares of stock or
membership interests of Tenant occurring by operation of Law or otherwise, and includes any merger,
acquisition, consolidation or reorganization, except as otherwise provided in this Subsection
below. Notwithstanding any provision of this Section to the contrary, an assignment for purposes
of this Article does not include any transfer of control of the stock or membership interests of
Tenant through (i) any public offering of shares of stock in Tenant in accordance with applicable
State and Federal law, rules, regulations and orders if thereafter the stock shall be listed and
publicly traded through the New York Stock Exchange or the NASDAQ national market; or (ii) public
sale of such stock effected through such Exchange or the NASDAQ national market. If Tenant is a
partnership, any change in the partners of Tenant shall be deemed to be an assignment.

     (e) For purposes of this Lease, a “Permitted Transferee” shall mean any Person which: (i) is
an Affiliate of Tenant; or (ii) is the corporation or other entity (the “Successor”) resulting from
a merger, conversion, consolidation or non-bankruptcy reorganization with Tenant; or (iii) is not a
Successor but is otherwise a deemed assignee due to a change of control under section 10.01(d)
above; or (iv) purchases, leases or acquires by way of exchange all or substantially all the assets
of Tenant as a going concern (the “Purchaser”). Notwithstanding anything to the contrary in
Sections 10.01(a) and (b), 10.02 and 10.03, provided there is no uncured Default under this Lease,
Tenant shall have the right, without the prior written consent of Landlord, to assign this Lease to
a Permitted Transferee or to sublease the Premises or any part thereof to a Permitted Transferee
provided that: (1) Landlord receives thirty (30) days prior written notice of an assignment or
sublease (including a pending
transaction described in subparts (i), (ii), (iii) or (iv) of this Section 10.01(e));
provided that Tenant may give notice in less than thirty (30) days in connection with a pending
transaction described in subparts (ii) and (iv) of this Section 10.01(e) to the extent that Tenant
is precluded, by the terms of the transaction or, if Tenant’s stock is publicly traded, by
applicable securities’ laws, from making disclosure of the transaction itself; (2) with respect to
an assignment of the Lease or a sublease of more than half the Premises to an entity described in
subparts (ii) or (iv) of this Section 10.01(e), the Permitted Transferee’s net worth is not less
than Tenant’s net worth (measured as of the most recent date for which financial statements
prepared in accordance with GAAP are available); (3) with respect to an assignment of the Lease or
a sublease of more than half the Premises to an entity described in
subparts (i) or (iii) of this
Section 10.01(e), Tenant (as the assignor or sublandord) continues in existence with a net worth
not less than Tenant’s net worth immediately prior to such assignment or subletting; (4) the
Permitted Transferee expressly assumes (except a Permitted Transferee which is a deemed assignee
under subpart (iii) of this Section 10.01(e) or which is a sublessee in the event of a sublease
under this Section 10.01(e)) in writing reasonably satisfactory to Landlord all of the obligations
of Tenant under this Lease and delivers such assumption to Landlord no later than fifteen (15) days
(or such lesser time as is appropriate in connection with a pending transaction described in
subparts (ii) and (iv) of this Section 10.01(e) to the extent that Tenant is precluded, by the
terms of the transaction or, if Tenant’s stock is publicly traded, by applicable securities’ laws,
from making

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disclosure of the transaction itself) prior to the effective date of the assignment; (5) Landlord
receives no later than five (5) days before the effective date a fully executed copy of the
applicable assignment or sublease agreement between Tenant and the Permitted Transferee; and (6)
promptly after Landlord’s written request, Tenant and the Permitted Transferee provide such
reasonable documents and information which Landlord reasonably requests for the purpose of
substantiating whether or not the assignment or sublease is to a Permitted Transferee. All
determinations of net worth for purposes of this Subsection shall
exclude any value attributable
to goodwill or going concern value. With respect to any proposed assignment under subparts (ii) or
(iv) of this Section 10.01 (e), Tenant shall pay Landlord, no later than fifteen (15) days prior
to the effective date of such proposed assignment or sublease, a processing fee of Three Thousand
Dollars ($3,000.00), which shall be Landlord’s earned fee whether or not the proposed assignment
or sublease is completed by Tenant.

     (f) With respect to any sublease to a Permitted Transferee pursuant to Subsection (e) above,
Tenant hereby irrevocably assigns to Landlord, effective upon any such sublease, all rent and
other payments due from subtenant under the sublease, provided however, that Tenant shall have a
license to collect such rent and other payments until the occurrence of a default by Tenant under
any of the provisions of the Lease, and notice to Tenant of such default shall not be a
prerequisite to Landlord’s right to collect subrent. At any time at Landlord’s option, Landlord
shall have the right to give notice to the subtenant of such assignment. Landlord shall credit
Tenant with any rent received by Landlord under such assignment but the acceptance of any payment
on account of rent from the subtenant as the result of any such default shall in no manner
whatsoever serve to release Tenant from any liability under the terms, covenants, conditions,
provisions or agreement under the Lease. No such payment of rent or any other payment by the
subtenant directly to Landlord and/or acceptance of such payment(s) by Landlord, regardless of the
circumstances or reasons therefor, shall in any manner whatsoever be deemed an attornment by the
subtenant to Landlord in the absence of a specific written agreement signed by Landlord to such an
effect. For purposes of this Subsection, any use or occupancy by a Permitted Transferee (unless it
is an assignee) without a formal sublease shall for the purposes of this Subsection be deemed to
be a sublease at the same rental rate as provided in the Lease.

10.02 RECAPTURE

Landlord shall have the option to exclude from the Premises covered by this Lease (“recapture”),
the space proposed to be sublet or subject to the assignment, so long as (i) the proposed transfer
is not to a Permitted Transferee in accordance with the provisions of Section 10.01 (e), and (ii)
the proposed sublease is for the remainder of the term of this Lease and Landlord recaptures the
entire portion of the Premises subject to the proposed sublease. If Landlord elects to recapture,
such recapture shall be effective as of the commencement date of such sublease or assignment,
Tenant shall surrender possession of the space proposed to be subleased or subject to the
assignment to Landlord on the effective date of recapture of such space from the Premises, such
date being the Termination Date for such space. Effective as of the date of recapture of any
portion of the Premises pursuant to this section, the Monthly Base Rent, Rentable Area of the
Premises and Tenant’s Share shall be adjusted accordingly.

10.03 EXCESS RENT

Except with respect to an assignment or sublease to a Permitted Transferee in accordance with the
provisions of Section 10.01 (e), Tenant shall pay Landlord on the first day of each month during
the term of the sublease or assignment, fifty percent (50%) of the amount by which the sum of all
rent and other consideration (direct or indirect) due from the subtenant or assignee for such month
exceeds: (i) that portion of the Monthly Base Rent and Rent Adjustments due under this Lease for
said month which is allocable to the space sublet or assigned; and (ii) the following costs and
expenses for the subletting or assignment of such space: (1) brokerage commissions and reasonable
attorneys’ fees and expenses, (2) the actual costs paid in making any improvements or substitutions
in the Premises required by any sublease or assignment; and (3) “free rent” periods, costs of any
inducements or concessions given to subtenant or assignee, moving costs, and other amounts in
respect of such subtenant’s or assignee’s other leases or occupancy arrangements. All such costs
and expenses shall be amortized over the term of the sublease or assignment pursuant to sound
accounting principles.

10.04 TENANT LIABILITY

In the event of any sublease or assignment, whether or not with Landlord’s consent, Tenant shall
not be released or discharged from any liability, whether past, present or future, under this
Lease, including any liability arising from the exercise of any renewal or expansion option, to
the extent such exercise is expressly permitted by Landlord. Tenant’s liability shall remain
primary, and in the event of default by any subtenant, assignee or successor of Tenant in
performance or observance of any of the covenants or conditions of this Lease, Landlord may
proceed directly against Tenant without the necessity of exhausting remedies against said
subtenant, assignee or successor. After any assignment, Landlord may consent to subsequent
assignments or subletting of this Lease, or amendments or modifications of this Lease with
assignees of Tenant, without notifying Tenant, or any successor of Tenant, and without obtaining
its or their consent thereto, and such action shall not relieve Tenant or any successor of Tenant
of liability under this Lease. If Landlord grants consent to such sublease or assignment, Tenant
shall pay all reasonable attorneys’ fees and expenses incurred by Landlord with respect to such
assignment or sublease. In addition, if Tenant has any options to extend the term of this Lease or
to add other space to the Premises, such options shall not be available to any subtenant or
assignee, directly or indirectly without Landlord’s express written
consent, which may be withheld in Landlord’s sole discretion.

10.05 ASSUMPTION AND ATTORNMENT

If Tenant
shall assign this Lease as permitted herein, the assignee shall expressly assume all of
the obligations of Tenant hereunder in a written instrument satisfactory to Landlord and furnished
to Landlord not later than fifteen (15) days prior to the
effective date of the assignment. If
Tenant shall sublease the Premises as permitted herein, Tenant shall, at Landlord’s option, within
fifteen (15) days following any request by Landlord, obtain and furnish to

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Landlord the written agreement of such subtenant to the effect that the subtenant will attorn to
Landlord and will pay all subrent directly to Landlord.

ARTICLE ELEVEN

DEFAULT AND REMEDIES

11.01 EVENTS OF DEFAULT

The occurrence or existence of any one or more of the following shall constitute a material
default and breach of the Lease (a “Default”) by Tenant under this Lease:

     (i) Tenant fails to pay any installment or other payment of Rent, including Rent
Adjustment Deposits or Rent Adjustments, within three business (3) days after written
notice to Tenant of such failure to pay, provided that after Landlord has twice sent such
notice to Tenant for failure to pay, thereafter such failure shall be a Default if Tenant
fails to pay any such installment or other payment of Rent, including Rent Adjustment
Deposits or Rent Adjustments, within three (3) business days after the date when the same
are due;

     (ii) Tenant fails to observe or perform any of the other covenants, conditions or
provisions of this Lease or the Workletter and, unless the default involves a hazardous
condition, which shall be cured forthwith or unless the failure to perform is a Default for
which this Lease specifies there is no cure or grace period, fails to cure such default
within thirty (30) days after written notice thereof to Tenant, provided that, if Tenant
has exercised reasonable diligence to cure such failure and such failure cannot reasonably
be cured within such thirty (30) day period despite reasonable diligence, Tenant shall not
be in default under this subsection so long as Tenant diligently and continuously
prosecutes the cure to completion;

     (iii) the interest of Tenant in this Lease is levied upon under execution or other
legal process;

     (iv) a petition is filed by or against Tenant to declare Tenant bankrupt or seeking a
plan of reorganization or arrangement under any Chapter of the Bankruptcy Act, or any
amendment, replacement or substitution therefor, or to delay payment of, reduce or modify
Tenant’s debts, which in the case of an involuntary action is not discharged within thirty
(30) days;

     (v) Tenant is declared insolvent by Law or any assignment of Tenant’s property is made
for the benefit of creditors;

     (vi) a receiver is appointed for Tenant or Tenant’s property, which appointment is not
discharged within thirty (30) days;

     (vii)
any action taken by or against Tenant to reorganize or modify Tenant’s capital
structure in a materially adverse way which in the case of an involuntary action is not
discharged within thirty (30) days; or

     (viii) upon the dissolution of Tenant.

11.02 LANDLORD’S REMEDIES

     (a) A Default shall constitute a breach of the Lease for which Landlord shall have the rights
and remedies set forth in this Section 11.02 and all other rights and remedies set forth in this
Lease or now or hereafter allowed by Law, whether legal or equitable, and all rights and remedies
of Landlord shall be cumulative and none shall exclude any other right or remedy.

     (b) With respect to a Default, at any time Landlord may terminate Tenant’s right to possession
by written notice to Tenant stating such election. Upon the termination of Tenant’s right to
possession pursuant to this Section 11.02, Tenant’s right to possession shall terminate and this
Lease shall terminate, and Tenant shall remain
liable as hereinafter provided. Upon such termination, Landlord shall have the right, subject
to applicable Law, to re-enter the Premises and dispossess Tenant and the legal representatives of
Tenant and all other occupants of the Premises by unlawful detainer or other summary proceedings,
or otherwise as permitted by Law, regain possession of the Premises and remove their property
(including their trade fixtures, personal property and those Tenant Additions which Tenant is
required or permitted to remove under Article Twelve), but Landlord shall not be obligated to
effect such removal, and such property may, at Landlord’s option, be stored elsewhere, sold or
otherwise dealt with as permitted by Law, at the risk of, expense of and for the account of Tenant,
and the proceeds of any sale shall be applied pursuant to Law. Landlord shall in no event be
responsible for the value, preservation or safekeeping of any such property. Tenant hereby waives
all claims for damages that may be caused by Landlord’s removing or storing Tenant’s personal
property pursuant to this Section or Section 12.01, and Tenant hereby indemnifies, and agrees to
defend, protect and hold harmless, the Indemnitees from any and all loss, claims, demands, actions,
expenses, liability and cost (including reasonable attorneys’ fees and expenses) arising out of or
in any way related to such removal or storage. Upon such written termination of Tenant’s right to
possession and this Lease, Landlord shall have the right to recover damages for Tenant’s Default as
provided herein or by Law, including the following damages provided by California Civil Code
Section 1951.2:

     (1) the worth at the time of award of the unpaid Rent which had been earned at the time
of termination;

     (2) the worth at the time of award of the amount by which the unpaid Rent which would
have been earned after termination until the time of award exceeds the amount of such Rent
loss that Tenant proves could reasonably have been avoided;

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     (3) the worth at the time of award of the amount by which the unpaid Rent for the
balance of the term of this Lease after the time of award exceeds the amount of such Rent
loss that Tenant proves could be reasonably avoided; and

     (4) any other amount necessary to compensate Landlord for all the detriment proximately
caused by Tenant’s failure to perform its obligations under this Lease or which in the
ordinary course of things would be likely to result therefrom. The word “rent” as used in
this Section 11.02 shall have the same meaning as the defined term Rent in this Lease. The
“worth at the time of award” of the amount referred to in clauses (1) and (2) above is
computed by allowing interest at the Default Rate. The worth at the time of award of the
amount referred to in clause (3) above is computed by discounting such amount at the
discount rate of the Federal Reserve Bank of San Francisco at the time of award plus one
percent (1%). For the purpose of determining unpaid Rent under clause (3) above, the monthly
Rent reserved in this Lease shall be deemed to be the sum of the Monthly Base Rent, and
monthly Storage Space Rent, if any, and the amounts last payable by Tenant as Rent
Adjustments for the calendar year in which Landlord terminated this Lease as provided
hereinabove.

     (c) Even if Tenant is in Default and/or has abandoned the Premises, this Lease shall continue
in effect for so long as Landlord does not terminate Tenant’s right to possession by written notice
as provided in Section 11.02(b) above, and Landlord may enforce all its rights and remedies under
this Lease, including the right to recover Rent as it becomes due under this Lease. In such
event, Landlord shall have all of the rights and remedies of a landlord under California Civil Code
Section 1951.4 (lessor may continue Lease in effect after Tenant’s Default and abandonment and
recover Rent as it becomes due, if Tenant has the right to sublet or assign, subject only to
reasonable limitations), or any successor statute. During such time as Tenant is in Default, if
Landlord has not terminated this Lease by written notice and if Tenant requests Landlord’s consent
to an assignment of this Lease or a sublease of the Premises, subject to Landlord’s option to
recapture pursuant to Section 10.02, Landlord shall not
unreasonably withhold its consent to such
assignment or sublease. Tenant acknowledges and agrees that the provisions of Article Ten shall
be deemed to constitute reasonable limitations of Tenant’s right to assign or sublet. Tenant
acknowledges and agrees that in the absence of written notice pursuant to Section 11.02(b) above
terminating Tenant’s right to possession, no other act of Landlord shall constitute a termination
of Tenant’s right to possession or an acceptance of Tenant’s surrender of the Premises, including
acts of maintenance or preservation or efforts to relet the Premises or the appointment of a
receiver upon initiative of Landlord to protect Landlord’s interest under this Lease or the
withholding of consent to a subletting or assignment, or terminating a subletting or assignment, if
in accordance with other provisions of this Lease.

     (d) In the event that Landlord seeks an injunction with respect to a breach or threatened
breach by Tenant of any of the covenants, conditions or provisions of this Lease, Tenant agrees to
pay the premium for any bond required in connection with such injunction.

     (e) Tenant hereby waives any and all rights to relief from forfeiture, redemption or
reinstatement granted by Law (including California Civil Code of Procedure Sections 1174 and 1179)
in the event of Tenant being evicted or dispossessed for any cause or in the event of Landlord
obtaining possession of the Premises by reason of Tenant’s Default or otherwise;

     (f) When this Lease requires giving or service of a notice of Default or of a failure of
Tenant to observe or perform any covenant, condition or provision of this Lease which will
constitute a Default unless Tenant so observes or performs within any applicable cure period, and
so long as the notice given or served provides Tenant the longer of any applicable cure period
required by this Lease or by statute, then the giving of any equivalent or similar statutory
notice, including any equivalent or similar notices required by California Code of Civil Procedure
Section 1161 or any similar or successor statute, shall replace and suffice as any notice required
under this Lease. When a statute requires service of a notice in a particular manner, service of
that notice (or a similar notice required by this Lease) in the manner required by Article
Twenty-four shall replace and satisfy the statutory service-of-notice procedures, except that any
notice of unlawful detainer required by California Code of Civil Procedure Section 1161 or any
similar or successor statute shall be served as required by Code of Civil Procedure Section 1162 or
any similar or successor statute, and for purposes of Code of Civil Procedure Section 1162 or any
similar or successor statute, Tenant’s “place of residence” and “usual place of business” shall
mean the address specified by Tenant for notice pursuant to Section 1.01 of this Lease, as changed
by Tenant pursuant to Article Twenty-four of this Lease.

     (g) The voluntary or other surrender or termination of this Lease, or a mutual termination or
cancellation thereof, shall not work a merger and shall terminate all or any existing assignments,
subleases, subtenancies or occupancies permitted by Tenant, except if and as otherwise specified in
writing by Landlord.

     (h) No delay or omission in the exercise of any right or remedy of Landlord upon any default
by Tenant, and no exercise by Landlord of its rights pursuant to Section 26.15 to perform any duty
which Tenant fails timely to perform, shall impair any right or remedy or be construed as a
waiver. No provision of this Lease shall be deemed waived by Landlord unless such waiver is in a
writing signed by Landlord. The waiver by Landlord of any breach of any provision of this Lease
shall not be deemed a waiver of any subsequent breach of the same or any other provision of this
Lease.

11.03 ATTORNEY’S FEES

In the event any party brings any suit or other proceeding with respect to the subject matter or
enforcement of this Lease, the prevailing party (as determined by the court, agency or other
authority before which such suit or proceeding is commenced) shall, in addition to such other
relief as may be awarded, be entitled to recover reasonable attorneys’ fees, expenses and costs of
investigation as actually incurred, including court costs, expert witness fees, costs and expenses
of investigation, and all reasonable attorneys’ fees, costs and expenses in any

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such suit or proceeding (including in any action or participation in or in connection with any case
or proceeding under the Bankruptcy Code, 11 United States Code
Sections 101 et seq., or any
successor statutes, in establishing or enforcing the right to indemnification, in appellate
proceedings, or in connection with the enforcement or collection of any judgment obtained in any
such suit or proceeding).

11.04 BANKRUPTCY

The following provisions shall apply in the event of the bankruptcy or insolvency of Tenant:

     (a) In connection with any proceeding under Chapter 7 of the Bankruptcy Code where the trustee
of Tenant elects to assume this Lease for the purposes of assigning it, such election or
assignment, may only be made upon compliance with the provisions of (b) and (c) below, which
conditions Landlord and Tenant acknowledge to be commercially reasonable. In the event the
trustee elects to reject this Lease then Landlord shall immediately be entitled to possession of
the Premises without further obligation to Tenant or the trustee.

     (b) Any election to assume this Lease under Chapter 11 or 13 of the Bankruptcy Code by Tenant
as debtor-in-possession or by Tenant’s trustee (the “Electing Party”) must provide for:

The Electing Party to cure or provide to Landlord adequate assurance that it will cure all
monetary defaults under this Lease within fifteen (15) days from the date of assumption and
it will cure all nonmonetary defaults under this Lease within thirty (30) days from the
date of assumption. Landlord and Tenant acknowledge such condition to be commercially
reasonable.

     (c) If the Electing Party has assumed this Lease or elects to assign Tenant’s interest under
this Lease to any other person, such interest may be assigned only if the intended assignee has
provided adequate assurance of future performance (as herein defined), of all of the obligations
imposed on Tenant under this Lease.

For the purposes hereof, “adequate assurance of future performance” means that Landlord has
ascertained that each of the following conditions has been satisfied:

     (i) The assignee has submitted a current financial statement, certified by its chief
financial officer, which shows a net worth and working capital in amounts sufficient to
assure the future performance by the assignee of Tenant’s obligations under this Lease; and

     (ii) Landlord has obtained consents or waivers from any third parties which may be
required under a lease, mortgage, financing arrangement, or other agreement by which
Landlord is bound, to enable Landlord to permit such assignment.

     (d) Landlord’s acceptance of rent or any other payment from any trustee, receiver, assignee,
person, or other entity will not be deemed to have waived, or waive, the requirement of Landlord’s
consent, Landlord’s right to terminate this Lease for any transfer of Tenant’s interest under this
Lease without such consent, or Landlord’s claim for any amount of Rent due from Tenant.

11.05 LANDLORD’S DEFAULT

Landlord shall be in default hereunder in the event Landlord has not begun and pursued with
reasonable diligence the cure of any failure of Landlord to meet its obligations hereunder within
thirty (30) days after the receipt by Landlord of written notice from Tenant of the alleged
failure to perform. In no event shall Tenant have the right to terminate or rescind this Lease as
a result of Landlord’s default as to any covenant or agreement contained in this Lease. Tenant
hereby waives such remedies of termination and rescission and hereby agrees that Tenant’s remedies
for default hereunder and for breach of any promise or inducement shall be limited to a suit for
damages and/or injunction. In addition, Tenant hereby covenants that, prior to the exercise of any
such remedies, it will give Mortgagee notice and a reasonable time to cure any default by
Landlord.

ARTICLE TWELVE

SURRENDER OF PREMISES

12.01 IN GENERAL

Upon the Termination Date, Tenant shall surrender and vacate the Premises immediately and deliver
possession thereof to Landlord in a clean, good and tenantable condition, ordinary wear and tear,
and damage caused by Landlord excepted. Tenant shall deliver to Landlord all keys to the Premises.
Tenant shall remove from the Premises all movable personal property of Tenant and Tenant’s trade
fixtures, including, subject to Section 6.04, cabling for any of the foregoing. Tenant shall be
entitled to remove such Tenant Additions which at the time of their installation Landlord and
Tenant agreed may be removed by Tenant. Tenant shall also remove such other Tenant Additions as
required by Landlord, including any Tenant Additions containing Hazardous Material. Tenant
immediately shall repair all damage resulting from removal of any of Tenant’s property,
furnishings, Tenant’s Personal Property or Tenant Additions, shall close all floor, ceiling and
roof openings and shall restore the Premises to a tenantable condition as reasonably determined by
Landlord. If any of the Tenant Additions which were installed by Tenant involved the lowering of
ceilings, raising of floors or the installation of specialized wall or floor coverings or lights,
then Tenant shall also be obligated to return such surfaces to their condition prior to the
commencement of this Lease. Tenant shall also be required to close any staircases or other
openings between floors. Notwithstanding any of the foregoing to the contrary, if so requested by
Tenant in writing (and prominently in all capital and bold lettering which also states that such
request is pursuant to Section 12.01 of the Lease) at the time Tenant requests approval of any
Tenant Work or subsequent Tenant Alterations, Landlord shall advise Tenant at the time of
Landlord’s approval of such Tenant Work or Tenant Alterations as to whether Landlord will require
that such Tenant Work or Tenant Alterations be removed by Tenant from the Premises; provided,
however,

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regardless of the foregoing, in any event, Landlord may require removal of any Tenant Additions
containing Hazardous Material and all Tenant’s trade fixtures, and, subject to Section 6.03,
cabling and wiring installed for Tenant’s personal property or trade fixtures. In the event
possession of the Premises is not delivered to Landlord when required hereunder, or if Tenant shall
fail to remove those items described above, Landlord may (but shall not be obligated to), at
Tenant’s expense, remove any of such property and store, sell or otherwise deal with such property
as provided in Section 11.02(b), including the waiver and indemnity obligations provided in that
Section, and undertake, at Tenant’s expense, such restoration work as Landlord deems necessary or
advisable.

12.02 LANDLORD’S RIGHTS

All property which may be removed from the Premises by Landlord shall be conclusively presumed to
have been abandoned by Tenant and Landlord may deal with such property as provided in Section
11.02(b), including the waiver and indemnity obligations provided in that Section. Tenant shall
also reimburse Landlord for all costs and expenses incurred by Landlord in removing any of Tenant
Additions required to be removed pursuant to Section 12.01 above and in restoring the Premises to
the condition required by this Lease at the Termination Date.

ARTICLE THIRTEEN

HOLDING OVER

Tenant shall pay Landlord the greater of (i) 150% of the monthly Rent payable for the month
immediately preceding the holding over (including increases for Rent Adjustments which Landlord
may reasonably estimate) or, (ii) 150% of the fair market rental value of the Premises as
reasonably determined by Landlord for each month or portion thereof that Tenant retains possession
of the Premises, or any portion thereof, after the Termination Date (without reduction for any
partial month that Tenant retains possession). Tenant shall also pay all damages sustained by
Landlord by reason of such retention of possession. The provisions of this Article shall not
constitute a waiver by Landlord of any re-entry rights of Landlord and Tenant’s continued
occupancy of the Premises shall be as a tenancy in sufferance.

ARTICLE FOURTEEN

DAMAGE BY FIRE OR OTHER CASUALTY

14.01 SUBSTANTIAL UNTENANTABILITY

     (a) If any fire or other casualty (whether insured or uninsured) renders all or a substantial
portion of the Premises or the Building untenantable, Landlord shall, with reasonable promptness
after the occurrence of such damage, estimate the length of time that will be required to
substantially complete the repair and restoration and shall by notice advise Tenant of such
estimate (“Landlord’s Notice”). If Landlord estimates that the amount of time required to
substantially complete such repair and restoration will exceed one hundred eighty (180) days from
the date such damage occurred, then Landlord, or Tenant if all or a substantial portion of the
Premises is rendered untenantable, shall have the right to terminate this Lease as of the date of
such damage upon giving written notice to the other at any time within twenty (20) days after
delivery of Landlord’s Notice, provided that if Landlord so chooses, Landlord’s Notice may also
constitute such notice of termination.

     (b) In the event that the Building is damaged or destroyed to the extent of more than
twenty-five percent (25%) of its replacement cost or to any extent if no insurance proceeds or
insufficient insurance proceeds are receivable by Landlord, or if the buildings at the Project
shall be damaged to the extent of fifty percent (50%) or more of the replacement value or to any
extent if no insurance proceeds or insufficient insurance proceeds are receivable by Landlord, and
regardless of whether or not the Premises be damaged, Landlord may elect by written notice to
Tenant given within thirty (30) days after the occurrence of the casualty to terminate this Lease
in lieu of so restoring the Premises, in which event this Lease shall terminate as of the date
specified in Landlord’s notice, which date shall be no later than sixty (60) days following the
date of Landlord’s notice.

     (c) Unless this Lease is terminated as provided in the preceding Subsections 14.01 (a) and
(b), Landlord shall proceed with reasonable promptness to repair and restore the Premises to its
condition as existed prior to such casualty, subject to reasonable delays for insurance adjustments
and Force Majeure delays, and also subject to zoning Laws and building codes then in effect.
Landlord shall have no liability to Tenant, and Tenant shall not be entitled to terminate this
Lease if such repairs and restoration are not in fact completed within the time period estimated by
Landlord so long as Landlord shall proceed with reasonable diligence to complete such repairs and
restoration.

     (d) Tenant acknowledges that Landlord shall be entitled to the full proceeds of any insurance
coverage, whether carried by Landlord or Tenant, for damages to the Premises, except for those
proceeds of
Tenant’s insurance of its own personal property and equipment which would be removable by
Tenant at the Termination Date. All such insurance proceeds shall be payable to Landlord whether or
not the Premises are to be repaired and restored, provided, however, if this Lease is not
terminated and the parties proceed to repair and restore Tenant Additions at Tenant’s cost, to the
extent Landlord received proceeds of Tenant’s insurance covering Tenant Additions, such proceeds
shall be applied to reimburse Tenant for its cost of repairing and restoring Tenant Additions.

     (e) Notwithstanding anything in this Article Fourteen to the contrary: (i) Landlord shall
have no duty pursuant to this Section to repair or restore any portion of any Tenant Additions or
to expend for any repair or restoration of the Premises or Building amounts in excess of insurance
proceeds paid to Landlord and available for repair or restoration; and (ii) Tenant shall not have
the right to terminate this Lease pursuant to this Section if any damage or destruction was caused
by the gross negligence or willful and wrongful act of Tenant, its agent or employees. Whether or
not the Lease is terminated pursuant to this Article Fourteen, in no event shall Tenant be entitled
to any compensation or damages for loss of the use of the whole or any part of the Premises or for
any

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inconvenience or annoyance occasioned by any such damage, destruction, rebuilding or restoration
of the Premises or the Building or access thereto.

     (f) Any repair or restoration of the Premises performed by Tenant shall be in
accordance with the provisions of Article Nine hereof.

14.02 INSUBSTANTIAL UNTENANTABILITY

Unless this Lease is terminated as provided in the preceding Subsections 14.01 (a) and (b), then
Landlord shall proceed to repair and restore the Building or the Premises other than Tenant
Additions, with reasonable promptness, unless such damage is to the Premises and occurs during the
last six (6) months of the Term, in which event either Tenant or Landlord shall have the right to
terminate this Lease as of the date of such casualty by giving written notice thereof to the other
within twenty (20) days after the date of such casualty. Notwithstanding the foregoing, Landlord’s
obligation to repair shall be limited in accordance with the provisions of Section 14.01 above.

14.03 RENT ABATEMENT

Except for (i) the willful and wrongful act of Tenant or its agents, employees, contractors or
invitees, or (ii) the gross negligence of Tenant or its agents, employees, contractors or invitees
only if and to the extent Landlord receives rental abatement insurance proceeds covering abatement
of the Rent hereunder, then, if all or any part of the Premises are rendered untenantable by fire
or other casualty and this Lease is not terminated, Monthly Base Rent and Rent Adjustments shall
abate for that part of the Premises which is untenantable on a per diem basis from the date of the
casualty until Landlord has Substantially Completed the repair and restoration work in the
Premises which it is required to perform, provided, that as a result of such casualty, Tenant does
not occupy the portion of the Premises which is untenantable during such period.

14.04 WAIVER OF STATUTORY REMEDIES

The provisions of this Lease, including this Article Fourteen, constitute an express agreement
between Landlord and Tenant with respect to any and all damage to, or destruction of, the Premises
or the Property or any part of either, and any Law, including Sections 1932(2), 1933(4), 1941 and
1942 of the California Civil Code, with respect to any rights or obligations concerning damage or
destruction shall have no application to this Lease or to any damage to or destruction of all or
any part of the Premises or the Property or any part of either, and are hereby waived.

ARTICLE FIFTEEN

EMINENT DOMAIN

15.01 TAKING OF WHOLE OR SUBSTANTIAL PART

In the event the whole or any substantial part of the Building or of the Premises is taken or
condemned by any competent authority for any public use or purpose (including a deed given in lieu
of condemnation) and is thereby rendered untenantable, this Lease shall terminate as of the date
title vests in such authority or any earlier date on which possession is required to be surrendered
to such authority, and Monthly Base Rent and Rent Adjustments shall be apportioned as of the
Termination Date. Further, if at least twenty-five percent (25%) of the rentable area of the
Project is taken or condemned by any competent authority for any public use or purpose (including a
deed given in lieu of condemnation), and regardless of whether or not the Premises be so taken or
condemned, Landlord may elect by written notice to Tenant to terminate this Lease as of the date
title vests in such authority or any earlier date on which possession is required to be surrendered
to such authority, and Monthly Base Rent and Rent Adjustments shall be apportioned as of the
Termination Date. Landlord may, without any obligation to Tenant, agree to sell or convey to the
taking authority the Premises, the Building, Tenant’s Phase, the Project or any portion thereof
sought by the taking authority, free from this Lease and the right of Tenant hereunder, without
first requiring that any action or proceeding be instituted or, if instituted, pursued to a
judgment. Notwithstanding anything to the contrary herein set forth, in the event the taking of the
Building or Premises is temporary (for less than the remaining term of the Lease), Landlord may
elect either (i) to terminate this Lease or (ii) permit Tenant to receive the entire award
attributable to the Premises in which case Tenant shall continue to pay Rent and this Lease shall
not terminate.

15.02 TAKING OF PART

In the event a part of the Building or the Premises is taken or condemned by any competent
authority (or a deed is delivered in lieu of condemnation) and this Lease is not terminated, the
Lease shall be amended to reduce or increase, as the case may be, the Monthly Base Rent and
Tenant’s Share to reflect the Rentable Area of the Premises or Building, as the case may be,
remaining after any such taking or condemnation. Landlord, upon receipt and to the extent of the
award in condemnation (or proceeds of sale) shall make necessary repairs and restorations to the
Premises (exclusive of Tenant Additions) and to the Building to the extent necessary to constitute
the portion of the Building not so taken or condemned as a complete architectural and economically
efficient unit. Notwithstanding the foregoing, if as a result of any taking, or a governmental
order that the grade of any street or alley adjacent to the Building is to be changed and such
taking or change of grade makes it necessary or desirable to substantially remodel or restore the
Building or prevents the economical operation of the Building, Landlord shall have the right to
terminate this Lease upon ninety (90) days prior written notice to Tenant.

15.03 COMPENSATION

Landlord shall be entitled to receive the entire award (or sale proceeds) from any such taking,
condemnation or sale without any payment to Tenant, and Tenant hereby assigns to Landlord
Tenant’s interest, if any, in such

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award; provided, however, Tenant shall have the right separately to pursue against the condemning
authority a separate award in respect of the loss, if any, to Tenant Additions paid for by Tenant
without any credit or allowance from Landlord, for fixtures or personal property of Tenant, or for
relocation or business interruption expenses, so long as there is no diminution of Landlord’s
award as a result.

ARTICLE SIXTEEN

INSURANCE

16.01 TENANT’S INSURANCE

Tenant, at Tenant’s expense, agrees to maintain in force, with a company or companies acceptable
to Landlord, during the Term: (a) Commercial General Liability Insurance on a primary basis and
without any right of contribution from any insurance carried by Landlord covering the Premises on
an occurrence basis against all claims for personal injury, bodily injury, death and property
damage, including contractual liability covering the indemnification provisions in this Lease.
Such insurance shall be for such limits that are reasonably required by Landlord from time to time
but not less than a combined single limit of Five Million and No/100 Dollars ($5,000,000.00); (b)
Workers’ Compensation and Employers’ Liability Insurance to the extent required by and in
accordance with the Laws of the State of California; (c) “All Risks” property insurance in an
amount adequate to cover the full replacement cost of all Tenant Additions to the Premises,
equipment, installations, fixtures and contents of the Premises in the event of loss; (d) In the
event a motor vehicle is to be used by Tenant in connection with its business operation from the
Premises, Comprehensive Automobile Liability Insurance coverage with limits of not less than Three
Million and No/100 Dollars ($3,000,000.00) combined single limit coverage against bodily injury
liability and property damage liability arising out of the use by or on behalf of Tenant, its
agents and employees in connection with this Lease, of any owned, non-owned or hired motor
vehicles; and (e) such other insurance or coverages as Landlord reasonably requires.

16.02 FORM OF POLICIES

Each policy referred to in 16.01 shall satisfy the following requirements. Each policy shall (i)
name Landlord and the Indemnitees as additional insureds (except Workers’ Compensation and
Employers’ Liability Insurance), (ii) be issued by one or more responsible insurance companies
licensed to do business in the State of California reasonably satisfactory to Landlord, (iii)
where applicable, provide for deductible amounts satisfactory to Landlord and not permit
co-insurance, (iv) shall provide that such insurance may not be canceled or amended without thirty
(30) days’ prior written notice to the Landlord, and (v) each policy of “All-Risks” property
insurance shall provide that the policy shall not be invalidated should the insured waive in
writing prior to a loss, any or all rights of recovery against any other party for losses covered
by such policies. Tenant shall deliver to Landlord, certificates of insurance and at Landlord’s
request, copies of all policies and renewals thereof to be maintained by Tenant hereunder, not
less than ten (10) days prior to the Commencement Date and not less than ten (10) days prior to
the expiration date of each policy.

16.03 LANDLORD’S INSURANCE

Landlord agrees to purchase and keep in full force and effect during the Term hereof, including
any extensions or renewals thereof, insurance under policies issued by insurers of recognized
responsibility, qualified to do business in the State of California on the Building in amounts not
less than the greater of eighty (80%) percent of the then full replacement cost (without
depreciation) of the Building (above foundations and excluding Tenant Additions to the Premises)
or an amount sufficient to prevent Landlord from becoming a co-insurer under the terms of the
applicable policies, against fire and such other risks as may be included in standard forms of all
risk coverage insurance reasonably available from time to time. Landlord agrees to maintain in
force during the Term, Commercial General Liability Insurance covering the Building on an
occurrence basis against all claims for personal injury, bodily injury, death and property damage.
Such insurance shall be for a combined single limit of Five Million and No/100 Dollars
($5,000,000.00). Neither Landlord’s obligation to carry such insurance nor the carrying of such
insurance shall be deemed to be an indemnity by Landlord with respect to any claim, liability,
loss, cost or expense due, in whole or in part, to Tenant’s negligent acts or omissions or willful
misconduct. Without obligation to do so, Landlord may, in its sole discretion from time to time,
carry insurance in amounts greater and/or for coverage additional to the coverage and amounts set
forth above.

16.04 WAIVER OF SUBROGATION

     (a) Landlord agrees that, if obtainable at no, or minimal, additional cost, and so long as the
same is permitted under the laws of the State of California, it will include in its “All Risks”
policies appropriate clauses pursuant to which the insurance companies (i) waive all right of
subrogation against Tenant with respect to losses payable under such policies and/or (ii) agree
that such policies shall not be invalidated should the insured waive in writing prior to a loss any
or all right of recovery against any party for losses covered by such policies.

     (b) Tenant agrees to include, if obtainable at no, or minimal, additional cost, and so long as
the same is permitted under the laws of the State of California, in its “All Risks” insurance
policy or policies on Tenant Additions to the Premises, whether or not removable, and on Tenant’s
furniture, furnishings, fixtures and other property removable by Tenant under the provisions of
this Lease appropriate clauses pursuant to which the insurance company or companies (i) waive the
right of subrogation against Landlord and/or any tenant of space in the Building with respect to
losses payable under such policy or policies and/or (ii) agree that such policy or policies shall
not be invalidated should the insured waive in writing prior to a loss any or all right of recovery
against any party for losses covered by such policy or policies. If Tenant is unable to obtain in
such policy or policies either of the clauses described in the preceding sentence, Tenant shall, if
legally possible and without necessitating a change in insurance carriers, have Landlord named in
such policy or policies as an additional insured. If Landlord shall be named as an additional
insured in accordance with the foregoing, Landlord agrees to endorse promptly to the order of
Tenant, without recourse, any check, draft, or order for the payment of money representing the

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proceeds of any such policy or representing any other payment growing out of or connected with
said policies, and Landlord does hereby irrevocably waive any and all rights in and to such
proceeds and payments.

     (c) Provided that Landlord’s right of full recovery under its policy or policies aforesaid
is not adversely affected or prejudiced thereby, Landlord hereby waives any and all right of
recovery which it might otherwise have against Tenant, its servants, agents and employees, for
loss or damage occurring to the Real Property and the fixtures, appurtenances and equipment
therein, except Tenant Additions, to the extent the same is covered by Landlord’s insurance,
notwithstanding that such loss or damage may result from the negligence or fault of Tenant, its
servants, agents or employees. Provided that Tenant’s right of full recovery under its aforesaid
policy or policies is not adversely affected or prejudiced thereby, Tenant hereby waives any and
all right of recovery which it might otherwise have against Landlord, its servants, and employees
and against every other tenant in the Real Property who shall have executed a similar waiver as
set forth in this Section 16.04 (c) for loss or damage to Tenant Additions, whether or not
removable, and to Tenant’s furniture, furnishings, fixtures and other property removable by
Tenant under the provisions hereof to the extent the same is covered or coverable by Tenant’s
insurance required under this Lease, notwithstanding that such loss or damage may result from the
negligence or fault of Landlord, its servants, agents or employees, or such other tenant and the
servants, agents or employees thereof.

     (d) Landlord and Tenant hereby agree to advise the other promptly if the clauses to be
included in their respective insurance policies pursuant to subparagraphs (a) and (b) above
cannot be obtained on the terms
hereinbefore provided and thereafter to furnish the other with a certificate of insurance or
copy of such policies showing the naming of the other as an additional insured, as aforesaid.
Landlord and Tenant hereby also agree to notify the other promptly of any cancellation or
change of the terms of any such policy which would affect such clauses or naming. All such
policies which name both Landlord and Tenant as additional insureds shall, to the extent
obtainable, contain agreements by the insurers to the effect that no act or omission of any
additional insured will invalidate the policy as to the other additional insureds.

16.05 NOTICE OF CASUALTY

Tenant shall give Landlord notice in case of a fire or accident in the Premises promptly after
Tenant is aware of such event.

ARTICLE SEVENTEEN

WAIVER OF CLAIMS AND INDEMNITY

17.01 WAIVER OF CLAIMS

To the extent permitted by Law, Tenant releases the Indemnitees from, and waives all claims for,
damage to person or property sustained by the Tenant or any occupant of the Premises or the
Property resulting directly or indirectly from any existing or future condition, defect, matter
or thing in and about the Premises or the Property, or any part of either, or any equipment or
appurtenance therein, or resulting from any accident in or about the Premises or the Property, or
resulting directly or indirectly from any act or neglect of any tenant or occupant of the
Property or of any other person, including Landlord’s agents and servants, except to the extent
caused by the gross negligence or willful and wrongful act of any of the Indemnitees. If any such
damage, whether to the Premises or the Property or any part of either, or whether to Landlord or
to other tenants in the Property, results from any act or neglect of Tenant, its employees,
servants, agents, contractors, invitees or customers, Tenant shall be liable therefor and
Landlord may, at Landlord’s option, repair such damage and Tenant shall, upon demand by Landlord,
as payment of additional Rent hereunder, reimburse Landlord within ten (10) days of demand for
the total cost of such repairs, in excess of amounts, if any, paid to Landlord under insurance
covering such damages. Tenant shall not be liable for any such damage caused by its acts or
neglect to the extent that Landlord or a tenant has recovered any amount of the damage from
proceeds of insurance policies and the insurance company has waived its right of subrogation
against Tenant.

17.02 INDEMNITY BY TENANT

To the extent permitted by Law, Tenant hereby indemnifies, and agrees to protect, defend and
hold the Indemnitees harmless, against any and all actions, claims, demands, liability, costs
and expenses, including reasonable attorneys’ fees and expenses for the defense thereof, arising
from Tenant’s occupancy of the Premises, from the undertaking of any Tenant Additions or repairs
to the Premises, from the conduct of Tenant’s business on the Premises, or from any breach or
default on the part of Tenant in the performance of any covenant or agreement on the part of
Tenant to be performed pursuant to the terms of this Lease, or from any willful act or
negligence of Tenant, its agents, contractors, servants, employees, customers or invitees, in or
about the Premises
or the Property or any part of either. In case of any action or proceeding brought against the
Indemnitees by reason of any such claim, upon notice from Landlord, Tenant covenants to defend
such action or proceeding by counsel chosen by Landlord, in Landlord’s sole discretion. Landlord
reserves the right to settle, compromise or dispose of any and all actions, claims and demands
related to the foregoing indemnity. The foregoing indemnity shall not operate to relieve an
Indemnitee of liability to the extent such liability is caused by the gross negligence or
willful and wrongful act of such Indemnitee. Further, the foregoing indemnity is subject to and
shall not diminish any waivers in effect in accordance with Section 16.04 by Landlord or its
insurers to the extent of amounts, if any, paid to Landlord under its “All-Risks” property
insurance.

17.03 WAIVER OF CONSEQUENTIAL DAMAGES

To the extent permitted by law, Tenant hereby waives and releases the Indemnitees from any
consequential damages, compensation or claims for inconvenience or loss of business, rents or
profits as a result of any injury or damage, whether or not caused by the willful and wrongful
act of any of the Indemnitees.

24

 

ARTICLE
EIGHTEEN

RULES AND REGULATIONS

18.01 RULES

Tenant agrees for itself and for its subtenants, employees, agents, and invitees to comply with all
reasonable rules and regulations for use of the Premises, the Building, the Phase and the Project
imposed by Landlord, as the same may be revised from time to time, including the following: (a)
Tenant shall comply with all of the requirements of Landlord’s emergency response plan, as the same
may be amended from time to time; and (b) Tenant shall not place any furniture, furnishings,
fixtures or equipment in the Premises in a manner so as to obstruct the windows of the Premises to
cause the Building, in Landlord’s good faith determination, to appear unsightly from the exterior.
Such rules and regulations are and shall be imposed for the cleanliness, good appearance, proper
maintenance, good order and reasonable use of the Premises, the Building, the Phase and the Project
and as may be necessary for the enjoyment of the Building and the Project by all tenants and their
clients, customers, and employees.

18.02 ENFORCEMENT

Nothing in this Lease shall be construed to impose upon the Landlord any duty or obligation to
enforce the rules and regulations as set forth above or as hereafter adopted, or the terms,
covenants or conditions of any other lease as against any other tenant, and the Landlord shall not
be liable to the Tenant for violation of the same by any other tenant, its servants, employees,
agents, visitors or licensees. Landlord shall use reasonable efforts to enforce the rules and
regulations of the Building in a uniform and non-discriminatory manner.

ARTICLE NINETEEN

LANDLORD’S RESERVED RIGHTS

Landlord shall have the following rights exercisable without notice to Tenant and without
liability to Tenant for damage or injury to persons, property or business and without being deemed
an eviction or disturbance of Tenant’s use or possession of the Premises or giving rise to any
claim for offset or abatement of Rent: (1) to change the Building’s name or street address upon
thirty (30) days’ prior written notice to Tenant; (2) to install, affix and maintain all signs on
the exterior and/or interior of the Building; (3) to designate and/or approve prior to
installation, all types of signs, window shades, blinds, drapes, awnings or other similar items,
and all internal lighting that may be visible from the exterior of the Premises; (4) upon
reasonable notice to Tenant, to display the Premises to prospective purchasers at reasonable hours
at any time during the Term and to prospective tenants at reasonable hours during the last twelve
(12) months of the Term; (5) to grant to any party the exclusive right to conduct any business or
render any service in or to the Building, provided such exclusive right shall not operate to
prohibit Tenant from using the Premises for the purpose permitted hereunder; (6) to change the
arrangement and/or location of entrances or passageways, doors and doorways, corridors, elevators,
stairs, washrooms or public portions of the Building, and to close entrances, doors, corridors,
elevators or other facilities, provided that such action shall not materially and adversely
interfere with Tenant’s access to the Premises or the Building; (7) to have access for Landlord
and other tenants of the Building to any mail chutes and boxes located in or on the Premises as
required by any applicable rules of the United States Post Office; and (8) to close the Building
after Standard Operating Hours, except that Tenant and its employees and invitees shall be
entitled to admission at all times, under such regulations as Landlord prescribes for security
purposes.

ARTICLE TWENTY

ESTOPPEL CERTIFICATE

20.01 IN GENERAL

Within fifteen (15) days after request therefor by Landlord, Mortgagee or any prospective
mortgagee or owner, Tenant agrees as directed in such request to execute an Estoppel Certificate
in recordable form, binding upon Tenant, certifying (i) that this Lease is unmodified and in full
force and effect (or if there have been modifications, a description of such modifications and
that this Lease as modified is in full force and effect); (ii) the dates to which Rent has been
paid; (iii) that Tenant is in the possession of the Premises if that is the case; (iv) that
Landlord is not in default under this Lease, or, if Tenant believes Landlord is in default, the
nature thereof in detail; (v) that Tenant has no offsets or defenses to the performance of its
obligations under this Lease (or if Tenant believes there are any offsets or defenses, a full and
complete explanation thereof); (vi) that the Premises have been completed in accordance with the
terms and provisions hereof, that Tenant has accepted the Premises and the condition thereof and
of all improvements thereto and has no claims against Landlord or any other party with respect
thereto; (vii) that if an assignment of rents or leases has been served upon the Tenant by a
Mortgagee, Tenant will
acknowledge receipt thereof and agree to be bound by the provisions thereof; (viii) that Tenant
will give to the Mortgagee copies of all notices required or permitted to be given by Tenant to
Landlord; and (ix) to any other information reasonably requested.

20.02 ENFORCEMENT

In the event that Tenant fails to deliver an Estoppel Certificate within three (3) business days
after Tenant has received notice from Landlord of Tenant’s failure to deliver an Estoppel
Certificate within the time prescribed in Section 20.01 above, then such failure shall be a
Default for which there shall be no additional cure or grace period. In addition to any other
remedy available to Landlord, Landlord may impose a charge equal to $500.00 for each day that
Tenant fails to deliver an Estoppel Certificate and Tenant shall be deemed to have irrevocably
appointed Landlord as Tenant’s attorney-in-fact to execute and deliver the subject Estoppel
Certificate that Tenant has failed to deliver.

25

 

ARTICLE TWENTY-ONE

INTENTIONALLY OMITTED

ARTICLE TWENTY-TWO

REAL ESTATE BROKERS

Landlord and Tenant represent to each other that in connection with this Lease they are
represented by Tenant’s Broker identified in Section 1.01(19) and Landlord’s Broker identified in
Section 1.01(19), and that except for Tenant’s Broker and Landlord’s Broker, neither has dealt
with any real estate broker, sales person, or finder in connection with this Lease, and no such
person initiated or participated in the negotiation of this Lease. Landlord and Tenant hereby
indemnify and agree to protect, defend and hold the other harmless from and against all claims,
losses, damages, liability, costs and expenses (including, without limitation, reasonable
attorneys’ fees and expenses) by virtue of any broker, agent or other person claiming a commission
or other form of compensation by virtue of alleged representation of, or dealings or discussions
with, Landlord or Tenant, as applicable, with respect to the subject matter of this Lease, except
for Landlord’s Broker and except for a commission payable to Tenant’s Broker to the extent
provided for in a separate written agreement between Tenant’s Broker and Landlord’s Broker. Tenant
is not obligated to pay or fund any amount to Landlord’s Broker, and Landlord hereby agrees to pay
such commission, if any, to which Landlord’s Broker is entitled in connection with the subject
matter of this Lease pursuant to Landlord’s separate written agreement with Landlord’s Broker.
Such commission shall include an amount to be shared by Landlord’s Broker with Tenant’s Broker to
the extent that Tenant’s Broker and Landlord’s Broker have entered into a separate agreement
between themselves to share the commission paid to Landlord’s Broker by Landlord. The provisions
of this Section shall survive the expiration or earlier termination of the Lease.

ARTICLE TWENTY-THREE

MORTGAGEE PROTECTION

23.01 SUBORDINATION AND ATTORNMENT

This Lease is and shall be expressly subject and subordinate at all times to (i) any ground or
underlying lease of the Real Property, now or hereafter existing, and all amendments, extensions,
renewals and modifications to any such lease, and (ii) the lien of any mortgage or trust deed now
or hereafter encumbering fee title to the Real Property and/or the leasehold estate under any such
lease, and all amendments, extensions, renewals, replacements and modifications of such mortgage
or trust deed and/or the obligation secured thereby, unless such ground lease or ground lessor, or
mortgage, trust deed or Mortgagee, expressly provides or elects that the Lease shall be superior
to such lease or mortgage or trust deed. If any such mortgage or trust deed is foreclosed
(including any sale of the Real Property pursuant to a power of sale), or if any such lease is
terminated, upon request of the Mortgagee or ground lessor, as the case may be, Tenant shall
attorn to the purchaser at the foreclosure sale or to the ground lessor under such lease, as the
case may be, provided, however, that such purchaser or ground lessor shall not be (i) bound by any
payment of Rent for more than one month in advance except payments in the nature of security for
the performance by Tenant of its obligations under this Lease; (ii) subject to any offset, defense
or damages arising out of a default of any obligations of any preceding Landlord; or (iii) bound
by any amendment or modification of this Lease made without the written consent of the Mortgagee
or ground lessor; or (iv) liable for any security deposits not actually received in cash by such
purchaser or ground lessor. This subordination shall be self-operative and no further certificate
or instrument of subordination need be required by any such Mortgagee or ground lessor. In
confirmation of such subordination, however, Tenant shall execute promptly any reasonable
certificate or instrument that Landlord, Mortgagee or ground lessor may request. Tenant hereby
constitutes Landlord as Tenant’s attorney-in-fact to execute such certificate or instrument for
and on behalf of Tenant upon Tenant’s failure to do so within fifteen (15) days of a request to do
so. Upon request by such successor in interest, Tenant shall execute and deliver reasonable
instruments confirming the attornment provided for herein.

23.02 MORTGAGEE PROTECTION

Tenant agrees to give any Mortgagee or ground lessor, by registered or certified mail, a copy of
any notice of default served upon the Landlord by Tenant, provided that prior to such notice Tenant
has received notice (by way of service on Tenant of a copy of an assignment of rents and leases, or
otherwise) of the address of such Mortgagee or ground lessor. Tenant further agrees that if
Landlord shall have failed to cure such default within the time provided for in this Lease, then
the Mortgagee or ground lessor shall have an additional thirty (30) days after receipt of notice
thereof within which to cure such default or if such default cannot be cured within that time, then
such additional notice time as may be necessary, if, within such thirty (30) days, any Mortgagee or
ground lessor has commenced and is diligently pursuing the remedies necessary to cure such default
(including commencement of foreclosure proceedings or other proceedings to acquire possession of
the Real Property, if necessary to effect such cure). Such period of time shall be extended by any
period within which such Mortgagee or ground lessor is prevented from commencing or pursuing such
foreclosure proceedings or other proceedings to acquire possession of the Real Property by reason
of Landlord’s bankruptcy. Until the time allowed as aforesaid for Mortgagee or ground lessor to
cure such defaults has expired without cure, Tenant shall have no right to, and shall not,
terminate this Lease on account of default. This Lease may not be modified or amended so as to
reduce the Rent or shorten the Term, or so as to adversely affect in any other respect to any
material extent the rights of the Landlord, nor
shall this Lease be canceled or surrendered, without the prior written consent, in each instance,
of the ground lessor or the Mortgagee.

ARTICLE TWENTY-FOUR

NOTICES

     (a) All notices, demands or requests provided for or permitted to be given pursuant to
this Lease must be in writing and shall be personally delivered, sent by Federal Express or other
reputable overnight courier

26

 

service, or mailed by first class, registered or certified United States mail, return receipt
requested, postage prepaid.

     (b) All notices, demands or requests to be sent pursuant to this Lease shall be deemed to have
been properly given or served by delivering or sending the same in accordance with this Section,
addressed to the parties hereto at their respective addresses listed in Sections 1.01(2) and (3).

     (c) Notices, demands or requests sent by mail or overnight courier service as described above
shall be effective upon deposit in the mail or with such courier service. However, the time period
in which a response to any such notice, demand or request must be given shall commence to run from
(i) in the case of delivery by mail, the date of receipt on the return receipt of the notice,
demand or request by the addressee thereof, or (ii) in the case of delivery by Federal Express or
other overnight courier service, the date of acceptance of delivery by an employee, officer,
director or partner of Landlord or Tenant. Rejection or other refusal to accept or the inability
to deliver because of changed address of which no notice was given, as indicated by advice from
Federal Express or other overnight courier service or by mail return receipt, shall be deemed to be
receipt of notice, demand or request sent. Notices may also be served by personal service upon any
officer, director or partner of Landlord or Tenant, and shall be effective upon such service.

     (d) By giving to the other party at least thirty (30) days written notice thereof, either
party shall have the right from time to time during the term of this Lease to change their
respective addresses for notices, statements, demands and requests, provided such new address shall
be within the United States of America.

ARTICLE TWENTY-FIVE

EXERCISE FACILITY

Tenant agrees to inform all employees of Tenant of the following: (i) the exercise facility is
available for the use of the employees of tenants of the Project only and for no other person; (ii)
use of the facility is at the risk of Tenant or Tenant’s employees, and all users must sign a
release; (iii) the facility is unsupervised; and (iv) users of the facility must report any needed
equipment maintenance or any unsafe conditions to the Landlord immediately. Landlord may
discontinue providing such facility at Landlord’s sole option at any time without incurring any
liability. As a condition to the use of the exercise facility, Tenant and each of Tenant’s
employees that uses the exercise facility shall first sign a written release in form and substance
acceptable to Landlord. Landlord may change the rules and/or hours of the exercise facility at any
time, and Landlord reserves the right to deny access to the exercise facility to anyone due to
misuse of the facility or noncompliance with rules and regulations of the facility. To the extent
permitted by Law, Tenant hereby indemnifies, and agrees to protect, defend and hold the Indemnitees
harmless, against any and all actions, claims, demands, liability, costs and expenses, including
reasonable attorneys’ fees and expenses for the defense thereof, arising from use of the exercise
facility in the Project by Tenant, Tenant’s employees or invitees, except to the extent due to the
gross negligence or willful and wrongful act of Landlord or Indemnitees. In case of any action or
proceeding brought against the Indemnitees by reason of any such claim, upon notice from Landlord,
Tenant covenants to defend such action or proceeding by counsel chosen by Landlord, in Landlord’s
sole discretion. Landlord reserves the right to settle, compromise or dispose of any and all
actions, claims and demands related to the foregoing indemnity.

ARTICLE TWENTY-SIX

MISCELLANEOUS

26.01 LATE CHARGES

     (a) The Monthly Base Rent, Rent Adjustments and Rent Adjustment Deposits shall be due when and
as specifically provided above. Except for such payments and late charges described below, which
late charge shall be due when provided below (without notice or demand), all other payments
required hereunder to Landlord shall be paid within ten (10) days after Landlord’s demand therefor.
All Rent and charges, except late charges, not paid when due shall bear interest from the date due
until the date paid at the Default Rate in effect on the date such payment was due.

     (b) In the event Tenant is more than five (5) days late in paying any installment of Rent due
under this Lease, Tenant shall pay Landlord a late charge equal to five percent (5%) of the
delinquent installment of Rent. The parties agree that (i) such delinquency will cause Landlord to
incur costs and expenses not contemplated herein, the exact amount of which will be difficult to
calculate, including the cost and expense that will be incurred by Landlord in processing each
delinquent payment of rent by Tenant, and (ii) the amount of such late charge represents a
reasonable estimate of such costs and expenses and that such late charge shall be paid to Landlord
for each delinquent payment in addition to all Rent otherwise due hereunder. The parties further
agree that the payment of late charges and the payment of interest provided for in subparagraph (a)
above are distinct and separate from one another in that the payment of interest is to compensate
Landlord for its inability to use the money improperly withheld by Tenant, while the payment of
late charges is to compensate Landlord for its
additional administrative expenses in handling and processing delinquent payments.

     (c) Payment of interest at the Default Rate and/or of late charges shall not excuse or cure
any default by Tenant under this Lease, nor shall the foregoing provisions of this Article or any
such payments prevent Landlord from exercising any right or remedy available to Landlord upon
Tenant’s failure to pay Rent when due, including the right to terminate this Lease.

26.02 NO JURY TRIAL; VENUE; JURISDICTION

Each party hereto (which includes any assignee, successor, heir or personal representative of a
party) shall not seek a jury trial, hereby waives trial by jury, and hereby further waives any
objection to venue in the County in which the Project is located, and agrees and consents to
personal jurisdiction of the courts of the State of

27

 

California, in any action or proceeding or counterclaim brought by any party hereto against the
other on any matter whatsoever arising out of or in any way connected with this Lease, the
relationship of Landlord and Tenant, Tenant’s use or occupancy of the Premises, or any claim of
injury or damage, or the enforcement of any remedy under any statute, emergency or otherwise,
whether any of the foregoing is based on this Lease or on tort law. No party will seek to
consolidate any such action in which a jury has been waived with any other action in which a jury
trial cannot or has not been waived. It is the intention of the parties that these provisions shall
be subject to no exceptions. By execution of this Lease the parties agree that this provision may
be filed by any party hereto with the clerk or judge before whom any action is instituted, which
filing shall constitute the written consent to a waiver of jury trial pursuant to and in accordance
with Section 631 of the California Code of Civil Procedure. No party has in any way agreed with or
represented to any other party that the provisions of this Section will not be fully enforced in
all instances. The provisions of this Section shall survive the expiration or earlier termination
of this Lease.

26.03 DEFAULT UNDER OTHER LEASE

It shall be a Default under this Lease if Tenant or any Affiliate holding any other lease with
Landlord for premises in the Project defaults under such lease and as a result thereof such lease
is terminated or terminable.

26.04 OPTION

This Lease shall not become effective as a lease or otherwise until executed and delivered by both
Landlord and Tenant. The submission of the Lease to Tenant does not constitute a reservation of or
option for the Premises, but when executed by Tenant and delivered to Landlord, the Lease shall
constitute an irrevocable offer by Tenant in effect for fifteen (15) days to lease the Premises on
the terms and conditions herein contained.

26.05 TENANT AUTHORITY

Tenant represents and warrants to Landlord that it has full authority and power to enter into and
perform its obligations under this Lease, that the person executing this Lease is fully empowered
to do so, and that no consent or authorization is necessary from any third party. Landlord may
request that Tenant provide Landlord evidence of Tenant’s authority.

26.06 ENTIRE AGREEMENT

This Lease, the Exhibits and Riders attached hereto contain the entire agreement between Landlord
and Tenant concerning the Premises and there are no other agreements, either oral or written, and
no other representations or statements, either oral or written, on which Tenant has relied. This
Lease shall not be modified except by a writing
executed by Landlord and Tenant.

26.07 MODIFICATION OF LEASE FOR BENEFIT OF MORTGAGEE

If Mortgagee of Landlord requires a modification of this Lease which shall not result in any
increased cost or expense to Tenant or in any other material and adverse change in the rights and
obligations of Tenant hereunder, then Tenant agrees that the Lease may be so modified.

26.08 EXCULPATION

Tenant agrees, on its behalf and on behalf of its successors and assigns, that any liability or
obligation of Landlord in connection with this Lease shall only be enforced against Landlord’s
equity interest in the Property up to a maximum of Five Million Dollars ($5,000,000.00) and in no
event against any other assets of the Landlord, or Landlord’s officers or directors or partners,
and that any liability of Landlord with respect to this Lease shall be so limited and Tenant shall
not be entitled to any judgment in excess of such amount.

26.09 ACCORD AND SATISFACTION

No payment by Tenant or receipt by Landlord of a lesser amount than any installment or payment of
Rent due shall be deemed to be other than on account of the amount due, and no endorsement or
statement on any check or any letter accompanying any check or payment of Rent shall be deemed an
accord and satisfaction, and Landlord may accept such check or payment without prejudice to
Landlord’s right to recover the balance of such installment or payment of Rent or pursue any other
remedies available to Landlord. No receipt of money by Landlord from Tenant after the termination
of this Lease or Tenant’s right of possession of the Premises shall reinstate, continue or extend
the Term. Receipt or acceptance of payment from anyone other than Tenant, including an assignee of
Tenant, is not a waiver of any breach of Article Ten, and Landlord may accept such payment on
account of the amount due without prejudice to Landlord’s right to pursue any remedies available to
Landlord.

26.10 LANDLORD’S OBLIGATIONS ON SALE OF BUILDING

In the event of any sale or other transfer of the Building, Landlord shall be entirely freed and
relieved of all agreements and obligations of Landlord hereunder accruing or to be performed after
the date of such sale or transfer (provided, however, that Landlord shall not be freed and relieved
of its obligation for reimbursement of the Security to Tenant unless Landlord has transferred to
such transferee the unapplied balance of Tenant’s Security held by Landlord at such time), and any
remaining liability of Landlord with respect to this Lease shall be limited to Five Million Dollars
($5,000,000.00) and Tenant shall not be entitled to any judgment in excess of such amount.

26.11 BINDING EFFECT

Subject to the provisions of Article Ten, this Lease shall be binding upon and inure to the benefit
of Landlord and Tenant and their respective heirs, legal representatives, successors and permitted
assigns.

28

 

26.12 CAPTIONS

The Article and Section captions in this Lease are inserted only as a matter of convenience and in
no way define, limit, construe, or describe the scope or intent of such Articles and Sections.

26.13 TIME; APPLICABLE LAW; CONSTRUCTION

Time is of the essence of this Lease and each and all of its provisions. This Lease shall be
construed in accordance with the Laws of the State of California. If more than one person signs
this Lease as Tenant, the obligations hereunder imposed shall be joint and several. If any term,
covenant or condition of this Lease or the application thereof to any person or circumstance shall,
to any extent, be invalid or unenforceable, the remainder of this Lease, or the application of such
term, covenant or condition to persons or circumstances other than those as to which it is held
invalid or unenforceable, shall not be affected thereby and each item, covenant or condition of
this Lease shall be valid and be enforced to the fullest extent permitted by Law. Wherever the term
“including” or “includes” is used in this Lease, it shall have the same meaning as if followed by
the phrase “but not limited to”. The language in all parts of this Lease shall be construed
according to its normal and usual meaning and not strictly for or against either Landlord or
Tenant.

26.14 ABANDONMENT

In the event Tenant vacates or abandons the Premises but is otherwise in compliance with all the
terms, covenants and conditions of this Lease, Landlord shall (i) have the right to enter into the
Premises in order to show the space to prospective tenants, (ii) have the right to reduce the
services provided to Tenant pursuant to the terms of this Lease to such levels as Landlord
reasonably determines to be adequate services for an unoccupied premises and (iii) during the last
six (6) months of the Term, have the right to prepare the Premises for occupancy by another tenant
upon the end of the Term. Tenant expressly acknowledges that in the absence of written notice
pursuant to Section 11.02(b) or pursuant to California Civil Code Section 1951.3 terminating
Tenant’s right to possession, none of the foregoing acts of Landlord or any other act of Landlord
shall constitute a termination of Tenant’s right to possession or an acceptance of Tenant’s
surrender of the Premises, and the Lease shall continue in effect.

26.15 LANDLORD’S RIGHT TO PERFORM TENANT’S DUTIES

If Tenant fails timely to perform any of its duties under this Lease, Landlord shall have the right
(but not the obligation), to perform such duty on behalf and at the expense of Tenant without prior
notice to Tenant, and all sums expended or expenses incurred by Landlord in performing such duty
shall be deemed to be additional Rent under this Lease and shall be due and payable upon demand by
Landlord.

26.16 SECURITY SYSTEM

Landlord shall not be obligated to provide or maintain any security patrol or security system.
Landlord shall not be responsible for the quality of any such patrol or system which may be
provided hereunder or for damage or injury to Tenant, its employees, invitees or others due to the
failure, action or inaction of such patrol or system.

26.17 NO LIGHT, AIR OR VIEW EASEMENTS

Any diminution or shutting off of light, air or view by any structure which may be erected on lands
of or adjacent to the Project shall in no way affect this Lease or impose any liability on
Landlord.

26.18 RECORDATION

Neither this Lease, nor any notice nor memorandum regarding the terms hereof, shall be recorded by
Tenant. Any such unauthorized recording shall be a Default for which there shall be no cure or grace
period. Tenant agrees to execute and acknowledge, at the request of Landlord, a memorandum of this
Lease, in recordable form.

26.19 SURVIVAL

The waivers of the right of jury trial, the other waivers of claims or rights, the releases and the
obligations of Tenant under this Lease to indemnify, protect, defend and hold harmless Landlord
and/or Indemnitees shall survive the expiration or termination of this Lease, and so shall all
other obligations or agreements which by their terms survive expiration or termination of the
Lease.

29

 

26.20 EXHIBITS OR RIDERS

All exhibits, riders and/or addenda referred to in this Lease as an exhibit, addenda or rider
hereto or attached hereto, are hereby incorporated into and made a part of this Lease.

IN WITNESS WHEREOF, this Lease has been executed as of the date set forth in Section 1.01(4)
hereof.

	 	 	 	 	 	 	 	 	 
	TENANT:	 	LANDLORD:	 	 
	 
	Genomic Health, Inc.,

a Delaware corporation	 	Metropolitan Life Insurance Company,

a New York corporation	 	 
	 
	 	 	 	 	 	 	 	 
	By

	 	/s/ Randy Scott
 

Randy Scott

 

                            Print name
	 	BY
	 	/s/ Joel R. Redmon
 

Joel R. Redmon

 

                            Print name
	 	  
	Its

	 	Executive Chairman
 

	 	Its
	 	Director
 

	 	 
	(Chairman of Board, President or Vice President)	 	 	 	 	 	 
	 
	 	 	 	 	 	 	 	 
	By

	 	/s/ Brad Cole
 

	 	 	 	 	 	 
	 

	 	Brad Cole

 

                            Print name
	 	 	 	 	 	 
	Its

	 	COO/CFO
 

	 	 	 	 	 	 
	(Secretary, Assistant Secretary, CFO or Assistant Treasurer)	 	 

30

 

Exhibit A

Plan of Premises

Exhibit A
- Page 1

 

 

EXHIBIT B

WORKLETTER AGREEMENT

     This Workletter Agreement (“Workletter”) is attached to and a part of a certain Lease by and
between Metropolitan Life Insurance Company, a New York corporation, as Landlord, and Genomic
Health, Inc., a Delaware corporation, as Tenant, for the Premises (the “Lease”). Terms used herein
and not defined herein shall have the meaning of such terms as defined elsewhere in the Lease. For
purposes of this Workletter, references to “State” and “City” shall mean the State and City in
which the Building is located.

     1. AS
IS Condition; Delivery.

     Landlord
shall deliver the Premises broom clean in its current “as built” configuration with
existing build-out of the tenant space, with the Premises and the Building (including the “Base
Building”, as defined below) in their AS IS condition, without any express or implied
representations or warranties of any kind by Landlord, its brokers, manager or agents, or the
employees of any of them; and Landlord shall not have any obligation to construct or install any
tenant improvements or alterations or to pay for any such construction or installation except to
the extent expressly provided in this Workletter. For purposes hereof, the “Base Building”
(sometimes also referred to as the “Base Building Work”) shall mean the improvements made and work
performed during the Building’s initial course of construction and modifications thereto, excluding
all original and modified build-outs of any tenant spaces. Notwithstanding any provision of this
Workletter or the Lease to the contrary, if and to the extent that upon delivery of the Premises,

	 	(i)	 	the roof and roof membrane above the Premises;
	 
	 	(ii)	 	foundation (excluding slab) and structural components of the Base Building;
	 
	 	(iii)	 	Landlord’s fire sprinkler and life-safety systems, if any, of the Base Building;
	 
	 	(iv)	 	the electrical, water, sewer and plumbing systems of the Base Building serving the Premises
(but only from the local utility’s systems to the point of entry into the Premises or to the meter
or other point after which such system serves exclusively the Premises);
	 
	 	(v)	 	lighting of the Base Building within the Premises (which is acknowledged and agreed to exclude
any supplemental or special lighting installed by any prior tenant or occupant); and
	 
	 	(vi)	 	loading doors, if any, of the Base Building serving the Premises;

are not in good working order and condition, and if and to the extent that there is any water
damage to the walls, hard lid ceilings or ceiling tiles, except to the extent any of the foregoing
are to be removed, demolished or altered by Tenant, and within twenty (20) days after the Delivery
Date (as defined in Section 2 of Rider 2) Tenant gives Landlord written notice specifying what is
not in good operating condition, Landlord shall make necessary repairs to put such item or items in
good operating condition. Further, Tenant acknowledges and agrees that, subject to the provisions
of Section 2 of this Workletter, the existing HVAC equipment serving the Premises is delivered in
its AS IS condition, without any express or implied representations or warranties of any kind by
Landlord, its brokers, manager or agents, or the employees of any of them as to its condition, and
Landlord shall not have any obligation for repair or replacement with respect to the HVAC equipment
except to perform the repair and replacement of such HVAC equipment specified below as the Landlord
Work.

     2. Landlord Work.

     2.1. Notwithstanding any of the foregoing to the contrary, subject to delays caused by Force
Majeure or Tenant Delay, Landlord, at Landlord’s sole cost and expense, shall perform the work set
forth on Exhibit B-1 hereto (“Landlord Work”), and within sixty (60) days after the
Delivery Date shall Substantially Complete the Landlord Work and leave the affected area in
broom-clean condition with respect to Landlord Work (but Landlord shall not be obligated to do any
clean-up or refuse removal related to construction of Tenant Work).

     2.2. Tenant acknowledges and agrees that in order to deliver the Premises to Tenant on the schedule
contemplated by this Lease, preparation for and performance of the Landlord Work will require
access, work and construction within the Premises after delivery of possession to Tenant, and that
Landlord and Landlord’s representatives and contractors shall have the right to enter the Premises
at all times to perform such work until the Landlord Work is completed, and that such entry and
work shall not constitute an eviction of Tenant in whole or in part and shall in no way excuse
Tenant from performance of its obligations under the Lease. Tenant and Landlord acknowledge and
agree that the Landlord Work and necessary coordination and cooperation to accomplish it will cause
certain unavoidable level of disturbance, inconvenience, annoyance to Tenant’s use and enjoyment of
the Premises, and that in performing such Landlord Work Landlord shall use commercially reasonable
efforts not to unreasonably and materially disturb Tenant’s construction, installations and
business operations, if any. Tenant shall cooperate and coordinate with Landlord and Landlord’s
contractor(s) to allow the Landlord Work to proceed expeditiously. The costs of such cooperation
and coordination shall be at Tenant’s sole cost and expense.

     2.3. The Landlord Work shall be constructed in accordance with all applicable laws, in a good and
workmanlike manner and using new materials and equipment of good quality. Contemporaneously with or
within ten (10) days after Substantial Completion of the Landlord Work, Tenant shall have the right
to submit a written “punch list” to Landlord, setting forth any defective item of the Landlord
Work. Landlord shall complete with reasonable diligence “punch list” items mutually agreed upon by
Landlord and Tenant with respect to the

Exhibit B
- Page 1

 

 

Landlord Work. In addition, Landlord shall repair all latent defects in workmanship and materials
of the Landlord Work, provided that Tenant gives Landlord written notice of any such latent defects
within three (3) months after the date of Substantial Completion. For purposes of this Section, the
term “latent defects” shall mean defects which were not reasonably discoverable at the time the
“punchlist” was formulated. All construction and installation of the Landlord Work shall
immediately become and remain the property of Landlord.

     3. Tenant’s Plans.

     3.1. Description. At its expense, Tenant shall employ:

     (i) one or more architects reasonably satisfactory to Landlord and licensed by the State (“Tenant’s
Architect”) to prepare architectural drawings and specifications for all layout and Premises
improvements not included in, or requiring any change or addition to, the AS IS condition and
Landlord Work, if any.

     (ii) one or more engineers reasonably satisfactory to Landlord and licensed by the State (“Tenant’s
Engineers”) to prepare structural, mechanical and electrical working drawings and specifications
for all Premises improvements not included in, or requiring any change or addition to, the AS IS
condition and Landlord Work, if any.

All such drawings and specifications are referred to herein as “Tenant’s Plans”. Tenant’s Plans
shall be in form and detail sufficient to secure all applicable governmental approvals. Tenant’s
Architect shall be responsible for coordination of all engineering work for Tenant’s Plans and
shall coordinate with any consultants retained by Tenant in connection with the design and
installation of improvements to the Premises (the use of such consultants is subject to Landlord’s
consent), and Landlord’s architect or other representative to assure the consistency of Tenant’s
Plans with the Base Building Work and Landlord Work (if any).

Tenant shall pay Landlord, within ten (10) days of receipt of each invoice from Landlord, the cost
incurred by Landlord for Landlord’s architects and engineers to review Tenant’s Plans for
consistency of same with the Base Building Work and Landlord Work, if any. Tenant’s Plans shall
also include the following:

     (a) Final Space Plan: The “Final Space Plan” for the Premises shall include a full and accurate
description of room titles, floor loads, alterations to the Base Building or Landlord Work (if any)
or requiring any change or addition to the AS IS condition, and the dimensions and location of all
partitions, doors, aisles, plumbing (and furniture and equipment to the extent same affect floor
loading). The Final Space Plan shall (i) be compatible with the design, construction, systems and
equipment of the Base Building and Landlord Work, if any; (ii) specify only materials, equipment
and installations which are new and of a grade and quality no less than existing components of the
Building when they were originally installed (collectively, (i) and (ii) may be referred to as
“Building Standard” or “Building Standards”); (iii) comply with Laws, (iv) be capable of logical
measurement and construction, and (v) contain all such information as may be required for the
preparation of the Mechanical and Electrical Working Drawings and Specifications (including,
without limitation, a capacity and usage report, from engineers designated by Landlord pursuant to
Section 3.1(b). below, for all mechanical and electrical systems in the Premises).

     (b) Mechanical and Electrical Working Drawings and Specifications: Tenant shall employ engineers
approved by Landlord to prepare Mechanical and Electrical Working Drawings and Specifications
showing complete plans for electrical, life safety, automation, plumbing, water, and air cooling,
ventilating, heating and temperature control and shall employ engineers designated by Landlord to
prepare for Landlord a capacity and usage report (“Capacity Report”) for all mechanical and
electrical systems in the Premises.

     (c) Issued for Construction Documents: The “Issued for Construction Documents” shall consist of all
drawings (1/8" scale) and specifications necessary to construct all Premises improvements
including, without limitation, architectural and structural working drawings and specifications and
Mechanical and Electrical Working Drawings and Specifications and all applicable governmental
authorities plan check corrections.

     3.2. Approval by Landlord. Tenant’s Plans and any revisions thereof shall be subject to
Landlord’s approval, which approval or disapproval:

     (i) shall not be unreasonably withheld, provided however, that Landlord may disapprove Tenant’s
Plans in its sole and absolute discretion if they (a) adversely affect the structural integrity of
the Building, including applicable floor loading capacity; (b) adversely affect any of the Building
Systems (as defined below), the Common Areas or any other tenant space (whether or not currently
occupied); (c) fail to fully comply with Laws, (d) affect the exterior appearance of the Building;
(e) provide for improvements which do not meet or exceed the Building Standards; or (f) involve any
installation on the roof, or otherwise affect the roof, roof membrane or any warranties regarding
either. Building Systems collectively shall mean the structural, electrical, mechanical (including,
without limitation, heating, ventilating and air conditioning), plumbing, fire and life-safety
(including, without limitation, fire protection system and any fire alarm), communication, utility,
gas (if any), and security (if any) systems in the Building.

     (ii) shall not be delayed beyond ten (10) business days with respect to initial submissions and
major change orders (those which impact Building Systems or any other item listed in subpart (i) of
Section 3.2 above) and beyond five (5) business days with respect to required revisions and any
other change orders.

Exhibit B
- Page 2

 

 

If Landlord disapproves of any of Tenant’s Plans, Landlord shall advise Tenant of what Landlord
disapproves in reasonable detail. After being so advised by Landlord, Tenant shall submit a
redesign, incorporating the revisions required by Landlord, for Landlord’s approval. The approval
procedure shall be repeated as necessary until Tenant’s Plans are ultimately approved. Approval by
Landlord shall not be deemed to be a representation or warranty by Landlord with respect to the
safety, adequacy, correctness, efficiency or compliance with Laws of Tenant’s Plans. Tenant shall
be fully and solely responsible for the safety, adequacy, correctness and efficiency of Tenant’s
Plans and for the compliance of Tenant’s Plans with any and all Laws.

     3.3. Landlord Cooperation. Landlord shall cooperate with Tenant and make good faith efforts
to coordinate Landlord’s construction review procedures to expedite the planning, commencement,
progress and completion of Tenant Work. Landlord shall complete its review of each stage of
Tenant’s Plans and any revisions thereof and communicate the results of such review within the time
periods set forth in Section 3.2 above.

     3.4. City Requirements. Any changes in Tenant’s Plans which are made in response to
requirements of the applicable governmental authorities and/or changes which affect the Base
Building Work shall be immediately submitted to Landlord for
Landlord’s review and approval.

     3.5. “As-Built” Drawings and Specifications. A CADD-DXF diskette file and a set of mylar
reproducibles of all “as-built” drawings and specifications of Tenant’s Work in the Premises
(reflecting all field changes and including, without limitation, architectural, structural,
mechanical and electrical drawings and specifications) prepared by Tenant’s Architect and Engineers
or by Contractors (defined below) shall be delivered by Tenant at Tenant’s expense to the Landlord
within thirty (30) days after completion of the Tenant Work. If Landlord has not received such
drawings and diskette(s) within thirty (30) days, Landlord may give Tenant written notice of such
failure. If Tenant does not produce the drawings and diskette(s) within ten (10) days after
Landlord’s written notice, Landlord may, at Tenant’s sole cost which may be deducted from the
Allowance, produce the drawings and diskette(s) using Landlord’s personnel, managers, and outside
consultants and contractors. Landlord shall receive an hourly rate reasonable for such production.

4. Tenant Work.

     4.1. Tenant Work Defined. All tenant improvement work required by the Issued for
Construction Documents (including, without limitation, any approved changes, additions or
alterations pursuant to Section 7 below) is referred to in this Workletter as “Tenant Work.”

     4.2. Tenant to Construct. Tenant shall construct all Tenant Work pursuant to this
Workletter, and except to the extent modified by or inconsistent with express provisions of this
Workletter, pursuant with the provisions of the terms and conditions of Article Nine of the Lease,
governing Tenant Alterations (except to the extent modified by this Workletter) and all such Tenant
Work shall be considered “Tenant Alterations” for purposes of the Lease.

     4.3. Construction Contract. All contracts and subcontracts for
Tenant Work shall include any terms and conditions reasonably required by Landlord.

     4.4. Contractor. Tenant shall select one or more contractors to perform
the Tenant Work (“Contractor”) subject to Landlord’s prior written approval, which shall not unreasonably be withheld.

     4.5. Division of Landlord Work and Tenant Work. Tenant Work is
defined in Section 4.1. above and Landlord Work, if any, is defined in Section 2.

5. Tenant’s Expense.

     Tenant agrees to pay for all Tenant Work, including, without limitation, the costs of design
thereof, whether or not all such costs are included in the “Permanent Improvement Costs” (defined
below). Subject to the terms and conditions of this Workletter, Tenant shall apply the “Allowance”
(defined below) to payment of the Permanent Improvement Costs. Landlord shall provide Tenant a
tenant improvement allowance (“Allowance”) in the amount equal to Three Hundred Seven Thousand Two
Hundred Eighty and no/100 Dollars ($307,280.00). The Allowance shall be used solely to reimburse
Tenant for the Permanent Improvement Costs. The term “Permanent Improvement Costs” shall mean the
actual and reasonable costs of construction of that Tenant Work which constitutes permanent
improvements to the Premises, actual and reasonable costs of design thereof and governmental
permits therefor, costs incurred by Landlord for Landlord’s architects and engineers pursuant to
Section 3.1, and Landlord’s construction administration fee (defined in Section 8.10 below).
Provided, however, Permanent Improvement Costs shall exclude costs of “Tenant’s FF&E” (defined
below). For purposes of this Workletter, “Tenant’s FF&E” shall mean Tenant’s furniture,
furnishings, telephone systems, computer systems, equipment, any other personal property or
fixtures, and installation thereof, including, without limitation, “Tenant’s Personal Property”
described on Exhibit G hereto. If Tenant does not utilize one hundred percent (100%) of the
Allowance for Permanent Improvement Costs no later than January 31, 2011, Tenant shall have no
right to the unused portion of the Allowance.

6. Application and Disbursement of the Allowance.

     6.1. Tenant shall prepare a budget for all Tenant Work, including the Permanent Improvement Costs
and all other costs of the Tenant Work (“Budget”), which Budget shall be subject to the reasonable
approval of Landlord. Such Budget shall be supported by a guaranteed maximum price construction
contract and such other documentation as Landlord may require to evidence the total costs. To the
extent the Budget exceeds the available Allowance (“Excess Cost”), Tenant shall be solely
responsible for payment of such Excess Cost. Further, prior to any disbursement of the Allowance by
Landlord, Tenant shall pay and disburse its own funds for all that portion of the Permanent
Improvement Costs equal to the sum of (a) the Permanent Improvement

Exhibit B
- Page 3

 

 

Costs in excess of the Allowance; plus (b) the amount of “Landlord’s Retention” (defined below).
“Landlord’s Retention” shall mean an amount equal to fifteen percent (15%) of the Allowance, which
Landlord shall retain out of the Allowance and shall not be obligated to disburse unless and until
after Tenant has completed the Tenant Work and complied with Section 6.4 below. Further, Landlord
shall not be obligated to make any disbursement of the Allowance unless and until Tenant has
provided Landlord with (i) bills and invoices covering all labor and material expended and used in
connection with the particular portion of the Tenant Work for which Tenant has requested
reimbursement, (ii) an affidavit from Tenant stating that all of such bills and invoices have
either been paid in full by Tenant or are due and owing, and all such costs qualify as Permanent
Improvement Costs, (iii) contractors affidavit covering all labor and materials expended and used,
(iv) Tenant, contractors and architectural completion affidavits (as applicable), and (v) valid
mechanics’ lien releases and waivers pertaining to any completed portion of the Tenant Work which
shall be conditional or unconditional, as applicable, all as provided pursuant to Section 6.2 and
6.4 below.

     6.2. Upon Tenant’s full compliance with the provisions of Section 6, and if Landlord determines
that there are no applicable or claimed stop notices (or any other statutory or equitable liens of
anyone performing any of Tenant Work or providing materials for Tenant Work) or actions thereon,
Landlord shall disburse the applicable portion of the Allowance as follows:

     (a) In the event of conditional releases, to the respective contractor, subcontractor, vendor, or
other person who has provided labor and/or services in connection with the Tenant Work, upon the
following terms and conditions: (i) such costs are included in the Budget, are Permanent
Improvement Costs, are covered by the Allowance, and Tenant has completed and delivered to Landlord
a written request for payment, in form reasonably approved by Landlord, setting forth the exact
name of the contractor, subcontractor or vendor to whom payment is to be made and the date and
amount of the bill or invoice, (ii) the request for payment is accompanied by the documentation set
forth in Section 6.1; and (iii) Landlord, or Landlord’s appointed representative, has inspected and
approved the work for which Tenant seeks payment; or

     (b) In the event of unconditional releases, directly to Tenant upon the following terms and
conditions: (i) Tenant seeks reimbursement for costs of Tenant Work which have been paid by Tenant,
are included in the Budget, are Permanent Improvement Costs, and are covered by the Allowance; (ii)
Tenant has completed and delivered to Landlord a request for payment, in form reasonably approved
by Landlord, setting forth the name of the contractor, subcontractor or vendor paid and the date of
payment, (iii) the request for payment is accompanied by the documentation set forth in Section
6.1; and (iv) Landlord, or Landlord’s appointed representative, has inspected and approved the work
for which Tenant seeks reimbursement.

     6.3. Tenant shall provide Landlord with the aforementioned documents by the 15th of the month and
payment shall be made by the 30th day of the month following the month in which such documentation
is provided.

     6.4. Prior to Landlord disbursing the Landlord’s Retention to Tenant, Tenant shall submit to
Landlord the following items within thirty (30) days after completion of the Tenant Work: (i) “As
Built” drawings and specifications pursuant to Section 3.5 above, (ii) all unconditional lien
releases from all general contractor(s) and subcontractor(s) performing work, (iii) a “Certificate
of Completion” prepared by Tenant’s Architect, and (iv) a final budget with supporting
documentation detailing all costs associated with the Permanent Improvement Costs.

7.
Changes, Additions or Alterations.

     If Tenant desires to make any non-de minimis change, addition or alteration or desires to make any
change, addition or alteration to any of the Building Systems after approval of the Issued for
Construction Documents, Tenant shall prepare and submit to Landlord plans and specifications with
respect to such change, addition or alteration. Any such change, addition or alteration shall be
subject to Landlord’s approval in accordance with the provisions of Section 3.2 of this Workletter.
Tenant shall be responsible for any submission to and plan check and permit requirements of the
applicable governmental authorities. Tenant shall be responsible for payment of the cost of any
such change, addition or alteration if it would increase the Budget and Excess Cost previously
submitted and approved pursuant to Section 6 above.

8. Miscellaneous.

     8.1. Scope. Except as otherwise set forth in the Lease, this Workletter shall not apply to
any space added to the Premises by Lease option or otherwise.

     8.2. Tenant Work shall include (at Tenant’s expense subject to application of the Allowance towards
the costs of such items) for all of the Premises:

     (a) Landlord approved lighting sensor controls as necessary to meet applicable Laws;

     (b) Building Standard fluorescent fixtures in all Building office areas;

     (c) Building Standard meters for each of electricity and chilled water used by Tenant shall be
connected to the Building’s system and shall be tested and certified prior to Tenant’s occupancy of
the Premises by a State certified testing company;

     (d) Building Standard ceiling systems (including tile and grid) and;

     (e) Building Standard air conditioning distribution and Building Standard air terminal units.

Exhibit B
- Page 4

 

 

     8.3. Sprinklers. Subject to any terms, conditions and limitations set forth herein,
Landlord shall provide an operative sprinkler system consisting of mains, laterals, and heads “AS
IS” on the date of delivery of the Premises to Tenant. Tenant shall pay for piping distribution,
drops and relocation of, or additional, sprinkler system heads and Building firehose or firehose
valve cabinets, if Tenant’s Plans and/or any applicable Laws necessitate such.

     8.4. Floor Loading. Floor loading capacity shall be within building design capacity. Tenant may exceed floor
loading capacity with Landlord’s consent, at Landlord’s sole discretion and must, at Tenant’s sole cost and expense,
reinforce the floor as required for such excess loading.

     8.5. Work Stoppages. If any work on the Real Property other than Tenant Work is delayed, stopped or otherwise affected by
construction of Tenant Work, Tenant shall immediately take those actions necessary or desirable to eliminate such delay, stoppage
or effect on work on the Real Property other than Tenant Work.

     8.6. Life Safety. Tenant (or Contractor) shall employ the services of a fire and life-safety subcontractor reasonably
satisfactory to Landlord for all fire and life-safety work at the Building.

     8.7. Locks. Tenant may purchase locks, cylinders and keys for the Premises from its own
vendor, provided that (a) such vendor and the locks, cylinders and keys to be used are subject to
Landlord’s prior written approval; (b) of a make and model which are functional, operable and
compatible with Landlord’s master key system; (c) a master key or keys are provided to Landlord, of
which Landlord may place one such master key in the “knox box” for use by the fire department and
emergency personnel in the event of an emergency and may retain another key for Landlord’s use for
entry permitted under the Lease; and (d) the contact information for Tenant’s vendor for locks,
cylinders and keys used in the Premises shall be provided to Landlord with Tenant’s request for
approval.

     8.8. Authorized Representatives. Tenant has designated David Quinn to act as Tenant’s
representative with respect to the matters set forth in this Workletter. Such representative(s)
shall have full authority and responsibility to act on behalf of Tenant as required in this
Workletter. Tenant may add or delete authorized representatives upon five (5) business days notice
to Landlord.

     8.9. Access to Premises. After Landlord has recovered possession of the Premises from any
prior Tenant, prior to delivery of possession to Tenant, Tenant and its architects, engineers,
consultants, and contractors shall have access at reasonable times and upon advance notice and
coordination with the Building management, to the Premises for the purpose of planning Tenant Work.
Such access shall not in any manner interfere with Landlord Work, if any. Such access, and all acts
and omissions in connection with it, shall be subject to and governed by all other provisions of
the Lease, including, without limitation, Tenant’s indemnification obligations, insurance
obligations, etc, except for the payment of Base Rent and Additional Rent. To the extent that such
access by Tenant delays the Substantial Completion of the Landlord Work (if any), such delay shall
be a Tenant Delay and the Landlord Work shall be deemed Substantially Complete on the date such
Landlord Work would have been completed but for such access.

     8.10. Fee. Landlord shall receive a fee equal to two percent (2.0%) of the Allowance for
Landlord’s review and supervision of construction of the Tenant Work, which fee shall be paid by
Landlord applying two percent (2.0%) of the Allowance in payment thereof. Such fee is in addition
to Tenant’s reimbursement of costs incurred by Landlord pursuant to other provisions hereof,
including, without limitation, for Landlord’s architects and engineers to review Tenant’s Plans.

9. Force and Effect.

     The terms and conditions of this Workletter shall be construed to be a part of the Lease and shall
be deemed incorporated in the Lease by this reference. Should any inconsistency arise between this
Workletter and the Lease as to the specific matters which are the subject of this Workletter, the
terms and conditions of this Workletter shall control.

Exhibit B
- Page 5

 

 

EXHIBIT B-1

DESCRIPTION OF LANDLORD WORK

	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 
	Unit	 	 	 	 	 	 	 	 	 	 	 	 	 	 
	#	 	Make	 	Model	 	Serial#	 	Condition	 	Repairs	 	Loc	 	Type
	AC-7

	 	Carrier
	 	48TJD008-621GA
	 	2500G30077
	 	Determine when gas to unit is turned on
	 	Verify operational when gas to unit is turned
on. Remove & replace defective control board
with new.
	 	Roof
	 	Package
	 
	 	 	 	 	 	 	 	 	 	 	 	 	 	 
	AC-8

	 	Carrier
	 	48TJE004-611GA
	 	2400G24614
	 	Operational. Determine further when gas to unit is turned on
	 	Verify operational when gas to unit is turned on.
	 	Roof
	 	Package
	 
	 	 	 	 	 	 	 	 	 	 	 	 	 	 
	EF-1

	 	Cookson
	 	Mushroom Fan
	 	N.A.
	 	Defective HVAC belt
	 	Remove & replace defective HVAC belt with new.
Check for proper tension & alignment. Start &
verify operation.	 	 	 	 

General Repairs:

1. Remove and replace filters of all rooftop HVAC units.

2. Clean condenser coils of all rooftop HVAC units.

3. For all rooftop HVAC units, check condensate drains and piping for proper drainage, and service
or repair as necessary, including replacement of any missing drain pipe for proper drainage of
condensate to roof drain(s).

4. Replace HVAC belts of all rooftop HVAC units.

5. Perform air balance.

Exhibit B-1
- Page 1

 

 

EXHIBIT C

SITE PLAN OF PROJECT

Phase III, its buildings and square footages are not a part of the Project as defined in this
Lease, and are shown in this Exhibit for illustration only.

Exhibit C
- Page 1

 

 

EXHIBIT D

PERMITTED HAZARDOUS MATERIAL

Permitted Hazardous Material includes insignificant amounts of substances listed below so long as
(i) such substances are maintained only in such quantities as are reasonably necessary for Tenant’s
operations in the Premises, or such other specific quantity limit as specified below, (ii) such
substances are used, stored and handled strictly in accordance with the manufacturers’
instructions, industry standards and all applicable laws, (iii) such substances are not disposed of
in or about the Building or the Project in a manner which would constitute a release or discharge
thereof, and (iv) all such substances are removed from the Building and the Project by Tenant no
later than the Termination Date.

	 	 	 
	Type:	 	Quantity:
	 
	 	 
	Substances typically found or used in general office applications, to the extent the Premises is used for general offices

	 	as noted above

	 	 	 	 	 	 	 	 	 	 	 
	HazMat Classification	 	Common Chemical or Trade Name	 	Tot.	 	 	Unit
	CL-II
	 	Combustible Liquid	 	Acetic Acid	 	 	4	 	 	L
	CL-II
	 	Combustible Liquid	 	Isoamyl Alcohol	 	 	1	 	 	L
	CL-II; CORR-L
	 	Combustible Liquid; Corrosive Liquid	 	1,3-Diaminopropane	 	 	2	 	 	L
	CL-II; CORR-L
	 	Combustible Liquid; Corrosive Liquid	 	Ethylenediamine	 	 	1	 	 	L
	CL-IIIA
	 	Combustible Liquid	 	Diethylpyrocarbonate	 	 	0.5	 	 	L
	CL-IIIA
	 	Combustible Liquid	 	Dimethylsulfoxide	 	 	2	 	 	L
	CL-IIIA
	 	Combustible Liquid	 	RNaseZap	 	 	3.5	 	 	L
	CL-IIIA
	 	Combustible Liquid	 	Triethylamine/Acetate buffer	 	 	0.5	 	 	L
	CORR-L
	 	Corrosive Liquid	 	Ammonium Hydroxide solution	 	 	0.5	 	 	L
	CORR-L
	 	Corrosive Liquid	 	Bradford Reagent (protein dye reagent)	 	 	0.5	 	 	L
	CORR-L
	 	Corrosive Liquid	 	Formic Acid	 	 	1	 	 	L
	CORR-L
	 	Corrosive Liquid	 	Hydrochloric Acid	 	 	6	 	 	L
	CORR-L
	 	Corrosive Liquid	 	N,N’-Dimethylethylenediamine	 	 	0.025	 	 	kg
	CORR-L
	 	Corrosive Liquid	 	Phosphoric Acid	 	 	4	 	 	L
	CORR-L
	 	Corrosive Liquid	 	RNaseZap wipes	 	 	1	 	 	kg
	CORR-L
	 	Corrosive Liquid	 	Sodium Hydroxide solution	 	 	2	 	 	L
	CORR-L
	 	Corrosive Liquid	 	Spermidine	 	 	0.5	 	 	kg
	CORR-L
	 	Corrosive Liquid	 	Trifluoroacetic Acid	 	 	1	 	 	L
	CORR-L; CL-IIIA
	 	Corrosive Liquid; Combustible Liquid	 	Monoethanotamine	 	 	4	 	 	L
	CORR-L; HI TOX-L
	 	Corrosive Liquid; Highly Toxic Liquid	 	Phenol/chloroform solution (TRizol)	 	 	6	 	 	L
	CORR-L; HI TOX-L; CL-III
	 	Corrosive Liquid; Highly Toxic Liquid; Combustible Liquid	 	Phenol	 	 	4	 	 	L
	CORR-S
	 	Corrosive Solid	 	Sodium Hydroxide, Pellets	 	 	2	 	 	kg
	CORR-S
	 	Corrosive Solid	 	Tris(2-carboxyethyl)-phosphine hydrochloride	 	 	0.01	 	 	kg
	CRYO
	 	Cryogenic Solid	 	Carbon Dioxide, solid	 	 	250	 	 	Ibs
	CRYO
	 	Cryogenic Liquid	 	Nitrogen, Liquid	 	 	400	 	 	L
	FL-1B
	 	Flammable Liquid	 	Acetone	 	 	4	 	 	L
	FL-1B
	 	Flammable Liquid	 	Acetonitrile	 	 	16	 	 	L
	FL-IB
	 	Flammable Liquid	 	(±)-2-Butanol	 	 	2	 	 	L
	FL-IB
	 	Flammable Liquid	 	Ethyl Alcohol, 70-100%, blends	 	 	150	 	 	L
	FL-IB
	 	Flammable Liquid	 	Buffer RW1, Wash Buffer (guanidinium thiocyanate (2.5-10%); ethanol (2.5-10%)),

 Buffer Kit	 	 	1	 	 	L
	FL-IB
	 	Flammable Liquid	 	Cytoseal XYL, Mounting Medium, Xylene-based	 	 	1	 	 	L
	FL-IB
	 	Flammable Liquid	 	Eosin Y	 	 	0.05	 	 	kg
	FL-IB
	 	Flammable Liquid	 	Eosin Y, 1% Alcoholic Solution	 	 	6	 	 	L
	FL-IB
	 	Flammable Liquid	 	EZ-DeWax, Tissue Deparaffinization Solution, Ready-to-Use	 	 	1	 	 	L
	FL-IB
	 	Flammable Liquid	 	Harris Hematoxylin	 	 	15	 	 	L
	FL-IB
	 	Flammable Liquid	 	Isopropyl Alcohol	 	 	20	 	 	L
	FL-IB
	 	Flammable Liquid	 	Methyl Alcohol	 	 	8	 	 	L
	FL-IB
	 	Flammable Liquid	 	Triethylamine	 	 	2.5	 	 	L
	FL-IB
	 	Flammable Liquid	 	Xylenes	 	 	50	 	 	L
	FL-IC
	 	Flammable Liquid	 	Isoamyl Acetate	 	 	1	 	 	L
	FL-IC
	 	Flammable Liquid	 	n-Butanol	 	 	2	 	 	L

Exhibit D
- Page 1

 

 

	 	 	 	 	 	 	 	 	 	 	 
	HazMat Classification	 	Common Chemical or Trade Name	 	Tot.	 	 	Unit
	HI TOX-L
	 	Highly Toxic Liquid	 	Chloroform	 	 	6	 	 	L
	HI TOX-L
	 	Highly Toxic Liquid	 	Chloroform/lsoamyl Alcohol (24:1)	 	 	1	 	 	L
	HI TOX-L
	 	Highly Toxic Liquid	 	Ethidium Bromide solution	 	 	0.1	 	 	L
	HI TOX-L
	 	Highly Toxic Liquid	 	Tetramethylammonium Chloride solution	 	 	2.5	 	 	L
	HI TOX-S
	 	Highly Toxic Solid	 	Sodium Azide	 	 	0.1	 	 	kg
	NFG
	 	Non-Flammable Compressed Gas	 	Air, Compressed Gas	 	 	2000	 	 	cu ft
	NFG
	 	Non-Flammable Compressed Gas	 	Carbon Dioxide, Compressed Gas	 	 	300	 	 	Ibs
	NFG
	 	Non-Flammable Compressed Gas	 	Helium, Compressed Gas	 	 	450	 	 	cu ft
	OXY-L
	 	Oxidizing Liquid	 	Hydrogen Peroxide, <30%	 	 	0.1	 	 	L
	OXY-L; CORR-L
	 	Oxidizing Liquid; Corrosive Liquid	 	Bleach, Household (5-10% sodium hypochlorite)	 	 	20	 	 	L
	OXY-L; CORR-L
	 	Oxidizing Liquid; Corrosive Liquid	 	Nitric Acid	 	 	4	 	 	L
	OXY-S
	 	Oxidizing Solid	 	Sodium Perchlorate	 	 	1	 	 	kg
	TOX-L
	 	Toxic Liquid	 	1,4-Dithiothreitol	 	 	0.1	 	 	L
	TOX-L
	 	Toxic Liquid	 	Formalin, Neutral Buffered	 	 	10	 	 	L
	TOX-L
	 	Toxic Liquid	 	2-Mercaptoethanol	 	 	1	 	 	L
	TOX-L
	 	Toxic Liquid	 	Formamide	 	 	2	 	 	L
	TOX-L
	 	Toxic Liquid	 	N,N-Dimethylformamide	 	 	0.2	 	 	kg
	TOX-S
	 	Toxic Solid	 	Diethylenetriaminepentaacetic Acid	 	 	0.01	 	 	kg
	TOX-S
	 	Toxic Solid	 	Hexadecyltrimethylammonium Bromide	 	 	1	 	 	kg
	TOX-S
	 	Toxic Solid	 	Lithium Chloride	 	 	0.5	 	 	kg
	TOX-S
	 	Toxic Solid	 	o-Phenylenediamine	 	 	0.25	 	 	L
	CL-II
	 	Combustible Liquid	 	(+/-)-limoneme	 	 	10	 	 	gal
	TOX-S
	 	Toxic Solid	 	Potassium Dichromate	 	 	1	 	 	kg
	CORR-L
	 	Corrosive Liquid	 	1.0M Perchloric Acid Solution	 	 	1	 	 	L
	CL-IIIA
	 	Combustible Liquid	 	Soltrol 130 Isoparaffin	 	 	40	 	 	L
	CL-II
	 	Combustible Liquid	 	Soltrol 125 Isoparaffin	 	 	40	 	 	L
	CL-II
	 	Combustible Liquid	 	Soltrol 100 Isoparaffin	 	 	40	 	 	L
	FL-IB
	 	Flammable liquid	 	Soltrol 10 Isoparaffin	 	 	40	 	 	L
	CL-II
	 	Combustible Liquid	 	Shandon Xylene Substitute	 	 	40	 	 	L
	FL-IC
	 	Flammable liquid	 	Xylene Substitute, Neo-Clear	 	 	40	 	 	L
	FL-IB
	 	Flammable liquid	 	2,2,4-Trimethylpentane	 	 	4	 	 	L
	CL-II
	 	Combustible Liquid	 	Mineral Spirits, Odorless	 	 	40	 	 	L
	CL-II
	 	Combustible Liquid	 	Decane	 	 	10	 	 	L
	CL-IIIB
	 	Combustible Liquid	 	Tridecane	 	 	4	 	 	L
	CL-IIIA
	 	Combustible Liquid	 	Slidebrite	 	 	4	 	 	L
	CL-II
	 	Combustible Liquid	 	Paraclear Odorless Xylene Substitute	 	 	4	 	 	L
	FL-IB
	 	Flammable liquid	 	Clear Advantage	 	 	4	 	 	L
	CL-II
	 	Combustible Liquid	 	Envirene	 	 	4	 	 	L

Exhibit D
- Page 2

 

 

EXHIBIT E

FORM OF LETTER OF CREDIT ACCEPTABLE FROM SILICON VALLEY BANK

IRREVOCABLE STANDBY LETTER OF CREDIT NO. SVBSF                     

DATED:                                , 20          

BENEFICIARY:

METROPOLITAN LIFE INSURANCE COMPANY

REAL ESTATE INVESTMENTS

425 MARKET STREET, SUITE 1050

SAN FRANCISCO, CA 94105

APPLICANT:

GENOMIC HEALTH, INC.

301 PENOBSCOT DRIVE

REDWOOD CITY, CA 94063

			
	AMOUNT:	 	US$183,168.00 (ONE HUNDRED EIGHTY-THREE THOUSAND ONE HUNDRED SIXTY-EIGHT
AND NO/100 DOLLARS)

EXPIRATION DATE:                     , 200     

LOCATION: AT OUR COUNTERS IN SANTA CLARA, CALIFORNIA

DEAR SIR/MADAM:

WE HEREBY ESTABLISH THIS IRREVOCABLE STANDBY LETTER OF CREDIT IN FAVOR OF THE AFORESAID ADDRESSEE
(“BENEFICIARY”) FOR DRAWINGS UP TO US$183,168.00 (ONE HUNDRED EIGHTY-THREE THOUSAND ONE HUNDRED
SIXTY-EIGHT AND NO/100 DOLLARS) EFFECTIVE IMMEDIATELY. THIS LETTER OF CREDIT IS ISSUED, PRESENTABLE
AND PAYABLE AT OUR OFFICE AT: 3003 TASMAN DRIVE, MAIL SORT HF210, SANTA CLARA, CA 95054 ATTENTION:
GLOBAL FINANCIAL SERVICES — STANDBY LETTER OF CREDIT DEPARTMENT (THE BANK’S OFFICE), AND EXPIRES
WITH OUR CLOSE OF BUSINESS ON                      , 200     .

THE TERM “BENEFICIARY” INCLUDES ANY SUCCESSOR BY OPERATION OF LAW OF THE NAMED BENEFICIARY
INCLUDING, WITHOUT LIMITATION, ANY LIQUIDATOR, REHABILITATOR, RECEIVER OR CONSERVATOR.

WE HEREBY UNDERTAKE TO PROMPTLY HONOR YOUR SIGHT DRAFT(S) DRAWN ON US, INDICATING ‘
OUR CREDIT NO. SVBSF
        , FOR ALL OR ANY PART OF THIS CREDIT IF PRESENTED AT OUR
OFFICE SPECIFIED IN PARAGRAPH ONE ON OR BEFORE THE EXPIRY DATE OR ANY AUTOMATICALLY EXTENDED
EXPIRY DATE TOGETHER WITH THE ORIGINAL LETTER OF CREDIT AND ALL AMENDMENTS, IF ANY.

EXCEPT AS EXPRESSLY STATED HEREIN, THIS UNDERTAKING IS NOT SUBJECT TO ANY AGREEMENT, CONDITION
OR QUALIFICATION. THE OBLIGATION OF SILICON VALLEY BANK UNDER THIS LETTER OF CREDIT IS THE
INDIVIDUAL OBLIGATION OF SILICON VALLEY BANK, AND IS IN NO WAY CONTINGENT UPON REIMBURSEMENT WITH
RESPECT THERETO.

IT IS A CONDITION OF THIS LETTER OF CREDIT THAT IT IS DEEMED TO BE AUTOMATICALLY EXTENDED
WITHOUT AMENDMENT FOR ONE YEAR FROM THE EXPIRY DATE HEREOF, OR ANY FUTURE EXPIRATION DATE, UNLESS
AT LEAST THIRTY (30) DAYS PRIOR TO AN EXPIRATION DATE WE NOTIFY YOU BY REGISTERED MAIL/COURIER THAT
WE ELECT NOT TO CONSIDER THIS LETTER OF CREDIT EXTENDED FOR ANY SUCH ADDITIONAL PERIOD.

PARTIAL DRAWS ARE ALLOWED.

THIS ORIGINAL LETTER OF CREDIT MUST ACCOMPANY ANY DRAWINGS HEREUNDER FOR ENDORSEMENT OF THE
DRAWING AMOUNT AND WILL BE RETURNED TO THE BENEFICIARY UNLESS IT IS FULLY UTILIZED.

THIS LETTER OF CREDIT MAY BE TRANSFERRED ONE OR MORE TIMES BUT IN EACH INSTANCE TO A SINGLE
BENEFICIARY AND ONLY IN THE FULL AMOUNT AVAILABLE TO BE DRAWN UNDER THIS LETTER OF CREDIT. ANY SUCH
TRANSFER MAY BE EFFECTED ONLY UPON PRESENTATION TO US, THE ISSUING BANK, AT THE BANK’S OFFICE
SPECIFIED IN THE FIRST PARAGRAPH ABOVE, OF THE
ATTACHED EXHIBIT “A” DULY COMPLETED AND EXECUTED BY THE BENEFICIARY AND ACCOMPANIED BY THE ORIGINAL
LETTER OF CREDIT AND ALL AMENDMENT(S), IF ANY. ANY TRANSFER OF THIS LETTER OF CREDIT MAY NOT CHANGE
THE PLACE OF EXPIRATION OF THE LETTER OF CREDIT FROM OUR SPECIFIED OFFICE. EACH TRANSFER SHALL BE
EVIDENCED BY OUR ENDORSEMENT ON THE REVERSE OF THE ORIGINAL LETTER OF CREDIT AND WE SHALL FORWARD
THE ORIGINAL LETTER OF CREDIT SO ENDORSED TO THE TRANSFEREE. EACH SUCH TRANSFER WILL BE EFFECTED AT
NO COST TO THE BENEFICIARY OR TRANSFEREE. OUR TRANSFER FEE
1/4 OF

Exhibit E
- Page 1

 

 

1% OF THE TRANSFER AMOUNT (MINIMUM US$250.00) WILL BE FOR THE ACCOUNT OF THE APPLICANT. HOWEVER,
ANY TRANSFER IS NOT CONTINGENT UPON APPLICANT’S ABILITY TO PAY OUR TRANSFER FEE.

DRAFT(S) AND DOCUMENTS MUST INDICATE THE NUMBER AND DATE OF THIS LETTER OF CREDIT.

THIS LETTER OF CREDIT IS SUBJECT TO AND GOVERNED BY THE UNIFORM CUSTOMS AND PRACTICE FOR
DOCUMENTARY CREDITS (1993 REVISION), INTERNATIONAL CHAMBER OF COMMERCE, PUBLICATION NO. 500 AND THE
LAWS OF THE STATE OF NEW YORK AND, IN THE EVENT OF ANY CONFLICT, THE LAWS OF THE STATE OF NEW YORK
WILL CONTROL. IF THIS CREDIT EXPIRES DURING AN INTERRUPTION OF BUSINESS AS DESCRIBED IN  ARTICLE 17
OF SAID PUBLICATION 500, THE BANK HEREBY SPECIFICALLY AGREES TO EFFECT PAYMENT IF THIS CREDIT IS
DRAWN AGAINST WITHIN 30 DAYS AFTER THE RESUMPTION OF BUSINESS.

SILICON VALLEY BANK,

	 	 	 	 	 
	 

AUTHORIZED SIGNATURE

	 	 

AUTHORIZED SIGNATURE
	 	 

Exhibit E -
Page 2

 

EXHIBIT “A”

DATE:

			
	TO:	 	SILICON VALLEY BANK

3003 TASMAN DRIVE

SANTA CLARA, CA 95054

ATTN: GLOBAL FINANCIAL SERVICES

			
	RE:	 	     SILICON VALLEY BANK, SANTA CLARA, CALIFORNIA

     IRREVOCABLE STANDBY LETTER OF CREDIT NO. SVBSF           

     DATED
                    
     , 20      AMOUNT: US$                     .

GENTLEMEN:

FOR VALUE RECEIVED, THE UNDERSIGNED BENEFICIARY HEREBY IRREVOCABLY TRANSFERS TO:

 

(NAME OF TRANSFEREE)

 

(ADDRESS)

ALL RIGHTS OF THE UNDERSIGNED BENEFICIARY TO DRAW UNDER THE ABOVE LETTER OF CREDIT UP TO ITS
AVAILABLE AMOUNT AS SHOWN ABOVE AS OF THE DATE OF THIS TRANSFER.

BY THIS TRANSFER, ALL RIGHTS OF THE UNDERSIGNED BENEFICIARY IN SUCH LETTER OF CREDIT ARE
TRANSFERRED TO THE TRANSFEREE. TRANSFEREE SHALL HAVE THE SOLE RIGHTS AS BENEFICIARY THEREOF,
INCLUDING SOLE RIGHTS RELATING TO ANY AMENDMENTS, WHETHER INCREASES OR EXTENSIONS OR OTHER
AMENDMENTS, AND WHETHER NOW EXISTING OR HEREAFTER MADE. ALL AMENDMENTS ARE TO BE ADVISED DIRECT TO
THE TRANSFEREE WITHOUT NECESSITY OF ANY CONSENT OF OR NOTICE TO THE UNDERSIGNED BENEFICIARY.

THE ORIGINAL OF SUCH LETTER OF CREDIT IS RETURNED HEREWITH, AND WE ASK YOU TO ENDORSE THE TRANSFER
ON THE REVERSE THEREOF, AND FORWARD IT DIRECTLY TO THE TRANSFEREE WITH YOUR CUSTOMARY NOTICE OF
TRANSFER.

SINCERELY,

METROPOLITAN LIFE INSURANCE COMPANY

	 	 	 
	 

(SIGNATURE OF BENEFICIARY)**

	 	 

 

** THIS TRANSFER FORM, EXHIBIT “A”, MUST BE NOTARIZED BY A NOTARY PUBLIC

Exhibit E - Page 3

 

EXHIBIT F

FAIR MARKET RENTAL RATE

     1. Definition of Fair Market Rental Rate. “Fair Market Rental Rate” shall mean the
Monthly Base Rent equal to the monthly base rental per rentable square foot which a tenant would
pay and which a willing landlord would accept for first class office/R&D/laboratory space
comparable to the Premises in the Building and in other buildings of class A standards in Seaport
Centre, including for purposes of this Exhibit Phases I, II and III as described on Exhibit
C and excluding Seaport Plaza (“Applicable Market”) for the period for which such rental is to
be paid and for a lease on terms substantially similar to those of the Lease (including, without
limitation, those applicable to Taxes, Operating Expenses and exclusions, but also considering
so-called net and triple net leases, and leases utilizing operating expense stops or base years,
and making appropriate adjustment between such leases and this Lease, as described below), based on
prevailing market conditions in the Building and in other buildings of class A standards in the
Applicable Market at the time such determination is made (“Comparable Transactions”).
Without limiting the generality of the foregoing, Comparable Transactions shall be for a
term similar to the term of tenancy and for space comparable in use, floor levels, square footage
and location within the Building and in other buildings of class A standards in the Applicable
Market as the transaction for which Fair Market Rental Rate is being determined; however, leases of
unusual or odd shaped spaces shall not be considered. In any determination of Fair Market Rental
Rate, the stated or contract monthly net or base rental in Comparable Transactions shall be
appropriately adjusted to take into account the different terms and conditions prevailing in such
transactions and those present in the Lease, including, without limitation: (a) the extent to which
average annual expenses and taxes per rentable square foot payable by tenants in Comparable
Transactions vary from those payable by Tenant under the Lease, and so, for example, if the Lease
provides for payment of Rent Adjustments and/or certain Operating Expenses on the basis of
increases over a base year, then the rate of Monthly Base Rent under the Lease shall be based upon
a step-up to change the calendar year which serves as the base year for calculation of the base for
such Operating Expenses for the Option Term to be the full calendar year in which the Option Term
commences, and such step-up shall be considered in the determination of the Fair Market Rental
Rate; (b) tenant improvements, value of existing tenant improvements, the concessions, if any,
being given by landlords in Comparable Transactions, such as parking charge abatement, free rent or
rental abatement applicable after substantial completion of any tenant improvements (and no
adjustment shall be made for any free or abated rent during any construction periods), loans at
below-market interest rates, moving allowances, space planning allowances, lease takeover payments
and work allowances, as compared to any tenant improvement, refurbishment or repainting allowance
given to Tenant under the Lease for the space for which Fair Market Rental Rate is being
determined; (c) the brokerage commissions, fees and bonuses payable by landlords
in Comparable Transactions (whether to tenant’s agent, such landlord or any person or entity
affiliated with such landlord), as compared to any such amounts payable by Landlord to the
broker(s) identified with respect to the transaction for which Fair Market Rental Rate is being
determined; (d) the time value of money; (e) any material difference between the definition of
rentable area and the ratio of project rentable to useable square feet in Comparable Transactions,
as compared to such figures applicable to the space for which Fair Market Rental Rate is being
determined; and (f) the extent to which charges for parking by tenants in Comparable Transactions
vary from those payable by Tenant under the Lease.

     2. Sealed Estimates. In the event the Lease requires Fair Market Rental Rate to be
determined in accordance with this Exhibit, Landlord and Tenant shall meet within ten (10) business
days thereafter and each simultaneously submit to the other in a sealed envelope its good faith
estimate of Fair Market Rental Rate (the “Estimates”). If the higher Estimate is not more than
one hundred five percent (105%) of the lower Estimate, then Fair Market Rental Rate shall be the
average of the two Estimates. If such simultaneous submission of Estimates does not occur within
such ten (10) business day period, then either party may by notice to the other designate any
reasonable time within five (5) business days thereafter and any reasonable place at or near the
Building for such meeting to take place. In the event only one party submits an Estimate at that
meeting, such Estimate shall be Fair Market Rental. In the event neither party submits an
Estimate at that meeting, the transaction for which Fair Market Rental Rate is being determined
shall be deemed cancelled and of no further force or effect.

     3. Selection of Arbitrators. If the higher Estimate is more than one hundred five
percent (105%) of the lower Estimate, then either Landlord or Tenant may, by written notice to the
other within five (5) business days after delivery of Estimates at the meeting, require that the
disagreement be resolved by arbitration. In the event neither party gives such notice, the
transaction for which Fair Market Rental Rate is being determined shall be deemed cancelled and of
no further force or effect. Within five (5) business days after such notice, the parties shall
select as arbitrators three (3) mutually acceptable independent MAI appraisers with experience in
real estate activities, including at least five (5) years experience in appraising comparable space
in the Applicable Market (“Qualified Appraisers”). If the parties cannot timely agree on such
arbitrators, then within the following five (5) business days, each shall select and inform the
other party of one (1) Qualified Appraiser and within a third period of five (5) business days, the
two appraisers (or if only one (1) has been duly selected, such single appraiser) shall select as
arbitrators a panel of three additional Qualified Appraisers, which three arbitrators shall proceed
to determine Fair Market Rental Rate pursuant to Section 4 of this Exhibit. Both Landlord and
Tenant shall be entitled to present evidence supporting their respective positions to the panel of
three arbitrators.

     4. Arbitration Procedure. Once a panel of arbitrators has been selected as provided
above, then as soon thereafter as practicable each arbitrator shall select one of the two Estimates
as the one which, in its opinion, is closer to Fair Market Rental Rate. Upon an Estimate’s
selection by two (2) of the arbitrators, it shall be the applicable Fair Market Rental Rate and
such selection shall be binding upon Landlord and Tenant. If the arbitrators collectively determine
that expert advice is reasonably necessary to assist them in determining Fair Market Rental Rate,
then they may retain one or more qualified persons, including but not limited to legal counsel,
brokers, architects or engineers, to provide such expert advice. The party whose Estimate is not
chosen by the arbitrators shall pay the costs of the arbitrators and any experts retained by the
arbitrators. Any

Exhibit F - Page 1

 

fees of any counsel or expert engaged directly by Landlord or Tenant, however, shall be borne by
the party retaining such counsel or expert.

     5. Rent Pending Determination of Fair Market Rental Rate. In the event that the
determination of
Fair Market Rental Rate has not been concluded prior to commencement of the applicable rental
period for the applicable space for which the Fair Market Rental Rate is being determined, Tenant
shall pay Landlord Monthly Base Rent and Rent Adjustment Deposits as would apply under Landlord’s
Estimate pursuant to Section 2 of this Exhibit until the Fair Market Rental Rate is determined. In
the event that the Fair Market Rental Rate subsequently determined is different from the amount
paid for the applicable period, then within thirty (30) days after such determination, Tenant shall
pay Landlord any greater amounts due and Landlord shall credit Tenant (against the next Monthly
Base Rent installments due) for any reduction in the amounts due.

Exhibit F - Page 2

 

EXHIBIT G

TENANT’S PERSONAL PROPERTY

Tenant’s Personal Property shall mean the following items belonging to Tenant, it being
acknowledged that if any of the following are affixed to the Premises in the normal manner for such
item, it shall still be deemed to be Tenant’s Personal Property:

	1.	 	Water deionization/purification systems;
	 
	2.	 	Facility vacuum system;
	 
	3.	 	Facility clean dry air system;
	 
	4.	 	Telecommunications systems;
	 
	5.	 	Computer network systems;
	 
	6.	 	Waste neutralization and monitoring systems;
	 
	7.	 	Trash compactor system;
	 
	8.	 	Satellite and/or radio frequency signal receivers/transmitters;
	 
	9.	 	Compressed gas distribution system;
	 
	10.	 	Audio-visual equipment;
	 
	11.	 	Electronic security and monitoring systems;
	 
	12.	 	Back-up and emergency electrical power equipment;
	 
	13.	 	Laboratory casework including fume hoods;
	 
	14.	 	Moveable benches and tables;
	 
	15.	 	Office furniture and equipment;
	 
	16.	 	Bicycle lockers;
	 
	17.	 	Shower room lockers;
	 
	18.	 	Laboratory equipment including autoclaves, glass washers, ice makers, cage washers,
dryers, environmental chambers;
	 
	19.	 	Servery equipment (i.e., equipment used in food service, in the break area or kitchen area)
	 
	20.	 	Fermentation system equipment;
	 
	21.	 	Such other items installed in the Premises by Tenant at Tenant’s expense during the term of
the Lease as are agreed to in writing by Tenant and Landlord to be Tenant’s Personal Property.

Exhibit G - Page 1

 

EXHIBIT H

FORM OF LETTER OF CREDIT

	 	 	 
	 

	 	FOR INTERNAL IDENTIFICATION PURPOSES ONLY
	 
	 	 
	 

	 	Our No.                            Other                     
	 
	 	 
	 

	 	Applicant                                                                           
      

			
	TO:	 	Metropolitan Life Insurance
Company 

[Address] 

Attention: Director,
EIM

IRREVOCABLE LETTER OF CREDIT NO.                     

     We hereby establish this irrevocable Letter of Credit in favor of the aforesaid addressee
(“Beneficiary”) for drawings up to UNITED STATES $183,168.00 (ONE HUNDRED EIGHTY-THREE THOUSAND
ONE HUNDRED SIXTY-EIGHT AND NO/100 DOLLARS) effective immediately. This Letter of Credit is
issued, presentable and payable at our office at [issuing bank’s address in either San
Francisco or San Jose] and expires with our close of business on                     , 20      .

     The term “Beneficiary” includes any successor by operation of law of the named Beneficiary
including, without limitation, any liquidator, rehabilitator, receiver or conservator.

     We hereby undertake to promptly honor your sight draft(s) drawn on us, indicating our Credit
No.                     , for all or any part of this Credit if presented at our office specified in paragraph one on
or before the
expiry date or any automatically extended expiry date.

     Except as expressly stated herein, this undertaking is not subject to any agreement, condition
or qualification. The obligation of [issuing bank] under this Letter of Credit is the
individual obligation of [issuing bank], and is in
no way contingent upon reimbursement
with respect thereto.

     It is a condition of this Letter of Credit that it is deemed to be automatically extended
without amendment for one year from the expiry date hereof, or any future expiration date, unless
at least thirty (30) days prior to an expiration date we notify you by registered mail that we
elect not to consider this Letter of Credit renewed for any such additional period.

     This Letter of Credit is transferable by the Beneficiary and by any successive transferees at
no charge or cost to Beneficiary or any transferee. Transfers of this Letter of Credit are subject
to receipt of Beneficiary’s (and subsequently, transferee’s) instructions in the form attached
hereto as Schedule 1 accompanied by the original Letter of Credit and amendments(s) if any.

     This Letter of Credit is subject to and governed by the Laws of the State of New York and the
1993 revision of the Uniform Customs and Practice for Documentary Credits of the International
Chamber of Commerce (Publication 500) and, in the event of any conflict, the Laws of the State of
New York will control. If this Credit expires during an interruption of business as described in
article 17 of said Publication 500, the bank hereby specifically agrees to effect payment if this
Credit is drawn against within 30 days after the resumption of business.

	 	 	 	 	 
	 

	 	Very truly yours,	 	 
	 
	 	 	 	 
	 

	 	 

[issuing bank]
	 	 

Exhibit H - Page 1

 

Schedule 1 to Letter of Credit

[Bank
– then current issuer of Letter of Credit]

	 	 	 	 	 	 	 
	c/o
	 	 	 	 	 	 
	 	 	 	 	 
	 
	 	 	 	 	 	 
	 	 	 
	 
	 	 	 	 	 	 
	 	 	 
	 
	 	 	 	 	 	 
	Attention:	 	 	 
	 

	 	 	 	 

	 	 

Re: Irrevocable Letter of Credit No.                                         

Ladies & Gentlemen:

     The undersigned acknowledges receipt of your advice No.                                          of a credit issued in
our favor, the terms of which are satisfactory. We now irrevocably transfer the said credit and all
amendments and extensions thereof, if any, to:

 

[Name of Transferee]

 

[Address]

     You are to inform the transferee of this transfer and such transferee shall have sole rights
as beneficiary under the credit, including any amendments, extension or increases thereof, without
notice to or further assent from us.

     This transfer is at no charge or cost to Beneficiary or the transferee.

	 	 	 	 	 
	 	Yours very truly,

Beneficiary

 	 
	 	By:  	 	 

Exhibit H - Page 2

 

Exhibit I

701 GALVESTON EXPANSION SPACE
(as defined in Rider 2)

	Not Expansion Space

Exhibit I - Page 1

 

RIDER 1

COMMENCEMENT DATE AGREEMENT

Metropolitan Life Insurance Company, a New York corporation (“Landlord”), and Genomic Health, Inc.,
a Delaware corporation (“Tenant”), have entered into a certain Lease dated as of                                          (the “Lease”).

WHEREAS, Landlord and Tenant wish to confirm and memorialize the Commencement Date and Expiration
Date of the Lease as provided for in Section 2.02(b) of the Lease;

NOW, THEREFORE, in consideration of the foregoing and the mutual covenants contained herein and in
the Lease, Landlord and Tenant agree as follows:

     1. Unless otherwise defined herein, all capitalized terms shall have the same meaning ascribed
to them in the Lease.

     2. The Commencement Date of the Term of the Lease is                     .

     3. The Expiration Date of the Term of the Lease is                     .

     4. Tenant hereby confirms the following:

(a) That it has accepted possession of the premises pursuant to the terms of the
Lease;

(b) That the Landlord Work, if any, is Substantially Complete; and

(c) That the Lease is in full force and effect.

     5. Except as expressly modified hereby, all terms and provisions of the Lease are hereby
ratified and confirmed and shall remain in full force and effect and binding on the parties hereto.

     6. The Lease and this Commencement Date Agreement contain all of the terms, covenants,
conditions and agreements between the Landlord and the Tenant relating to the subject matter
herein. No prior other agreements or understandings pertaining to such matters are valid or of
any force and effect.

     IN WITNESS WHEREOF, Landlord and Tenant have executed this Commencement Date Agreement and
such execution and delivery have been duly authorized.

	 	 	 	 	 	 	 	 	 	 	 
	TENANT:	 	 	 	LANDLORD:	 	 
	 
	 	 	 	 	 	 	 	 	 	 
	Genomic Health, Inc.,	 	 	 	Metropolitan Life Insurance Company,	 	 
	a Delaware corporation	 	 	 	a New York corporation	 	 
	 
	 	 	 	 	 	 	 	 	 	 
	By

	 	 	 	 	 	By	 	 	 	 
	 

	 	 

	 	 	 	 	 	 

	 	 
	 
	 	 	 	 	 	 	 	 	 	 
	 

	 	 

Print name
	 	 	 	 	 	 

Print name
	 	 
	 
	 	 	 	 	 	 	 	 	 	 
	Its

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RIDER 2

ADDITIONAL PROVISIONS

     This Rider 2 (“Rider”) is attached to and a part of a certain Lease by and between
Metropolitan Life Insurance Company, a New York corporation, as Landlord, and Genomic Health,
Inc., a Delaware corporation (for purposes of this Rider, “Genomic”), as Tenant, for the Premises
as described therein (the “Lease”).

SECTION 1. DEFINED TERMS; FORCE AND EFFECT

Capitalized terms used in this Rider shall have the same meanings set forth in the Lease except as
otherwise specified herein and except for terms capitalized in the ordinary course of punctuation.
This Rider forms a part of the Lease. Should any inconsistency arise between this Rider and any
other provision of the Lease as to the specific matters which are the subject of this Rider, the
terms and conditions of this Rider shall control.

SECTION 2. PREMISES; CONDITION; DELIVERY; CONSTRUCTION PERIOD; COMMENCEMENT DATE

     (a) Landlord shall tender to Tenant possession of the Premises in the condition specified in
the Workletter (free of all prior occupants and their personal property) on February 1, 2010 (the
“Projected Delivery Date”). On the date Landlord actually tenders to Tenant possession of the
Premises (the “Delivery Date”), all the conditions and covenants of the Lease shall apply, and
Tenant shall observe and perform all conditions and covenants of the Lease, including all that are
specified to apply during the Term (for example only, Tenant’s insurance and indemnification
obligations), except as otherwise expressly provided in this Rider. During the period (the
“Construction Period”) from the Delivery Date until the Commencement Date, in recognition of
Tenant’s construction and installations in, and preparation of, the Premises for the use and
occupancy permitted by this Lease, Tenant shall not be obligated to pay Monthly Base Rent, Rent
Adjustment Deposits or Rent Adjustments. The Term of this Lease shall be as shown in Section
1.01(5) of the Basic Lease Provisions and the Commencement Date of the Term shall be the date set
forth in Section 1.01(6). To the extent permitted by Law and that Tenant obtains any and all
necessary approvals and permits for such use, during the Construction Period Tenant may use part of
the Premises for the conduct of business by up to thirty (30) employees of Tenant without
obligation to pay Monthly Base Rent for the space so used (“Temporary Space”), but Tenant shall be
obligated to pay its pro rata share of Rent Adjustment Deposits and Rent Adjustment with respect to
the Temporary Space based upon the number of square feet of Rentable Area of the Temporary Space to
the Rentable Area of the Building, Phase and Project.

     (b) Within thirty (30) days following the occurrence of the Commencement Date, upon request by
Landlord or Tenant, Tenant and Landlord shall enter into an agreement (which is attached to this
Lease as Rider 1) confirming the Commencement Date and the Expiration Date. If Tenant fails to
enter into such agreement, then the Commencement Date and the Expiration Date shall be the dates
designated by Landlord in such agreement.

     (c) If Landlord shall be unable to give possession of the Premises on the Projected Delivery
Date by reason of the following: (i) the holding over or retention of possession of any tenant,
tenants or occupants, or (ii) for any other reason beyond Landlord’s reasonable control, then
Landlord shall not be subject to any liability for the failure to give possession on said date.
Under such circumstances, the Commencement Date shall be delayed by a number of days equal to the
days of delay in Landlord’s delivery of possession to Tenant. No such failure to deliver possession
on the originally scheduled Projected Delivery Date shall affect the validity of this Lease or the
obligations of the Tenant hereunder.

SECTION 3. MONUMENT SIGNAGE.

     (a) Grant of Right. Notwithstanding any provision of Section 6.06 of the Lease to
the contrary, Tenant shall have the right to place Tenant identification on one line of the
existing, exterior monument sign (located on Chesapeake Drive) for the Building, subject to the
terms and conditions set forth in this Section (“Exterior Sign Right”).

     (b) General Conditions & Requirements. The size, type, style, materials, color,
method of installation and exact location of the sign, and the contractor for and all work in
connection with the sign, contemplated by this Section shall (i) be subject to Tenant’s compliance
with all applicable laws, regulations and ordinances and with any covenants, conditions and
restrictions of record which affect the Property; (ii) be subject to Tenant’s compliance with all
requirements of Landlord’s current Project signage criteria at the time of installation; (iii) be
consistent with the design of the Building and the Project; (iv) be further subject to Landlord’s
prior written consent. Tenant shall, at its sole cost and expense, procure, install, maintain in
first class appearance and condition, and remove such sign.

     (c) Removal & Restoration. Upon the expiration or termination of the Exterior Sign
Right, but in no event later than the expiration of the Term or earlier termination of the Lease,
Tenant shall, at its sole cost and expense, remove such sign and shall repair and restore the area
in which the sign was located to its condition prior to installation of such sign.

     (d) Right Personal. The Exterior Sign Right under this Section is personal to
Genomic, and may not be used by, and shall not be transferable or assignable (voluntarily or
involuntarily) to any person or entity.

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SECTION 4. EXPANSION OPTION FOR 701 GALVESTON.

     (a) Grant of Option. Landlord hereby grants Tenant one option to lease the 701
Galveston Expansion Space (defined below) upon and subject to the terms and conditions of this
Section (the “701 Galveston Expansion Option”), provided that at the time of exercise of such
option: (x) Tenant or a Permitted Transferee which has satisfied the requirements of Sections
10.01 and 10.05 of the Lease must be conducting regular, active, ongoing business in, and be in
occupancy (and occupancy by a subtenant, licensee or other party permitted or suffered by Tenant
shall not satisfy such condition) of the entire Premises; and (y) there has been no material
adverse change in Tenant’s financial position from such position as of the date of execution of the
Lease, as certified by Tenant’s independent certified public accountants, and as supported by
Tenant’s certified financial statements, copies of which shall be delivered to Landlord with
Tenant’s written notice exercising its right hereunder. Without limiting the generality of the
foregoing, Landlord may reasonably conclude there has been a material adverse change if Tenant’s
independent certified public accountants do not certify there has been no such change.
Notwithstanding anything to the contrary, the 701 Galveston Expansion Option shall be subject and
subordinate to the Prior Rights (defined below). Landlord and Tenant acknowledge that the 701
Galveston Expansion Space is, as of the date of this Lease, leased under that certain written lease
dated as of November 20, 2007, between Landlord, as landlord, and Vibrynt, Inc., as tenant, as
supplemented by that Commencement Date Agreement confirming, among other things, the scheduled
expiration date of February 20, 2011 of the initial term of such lease (collectively, the “Existing
701 Lease”). The term “Prior Rights” shall mean: (i) any extension of the term of the Existing
701 Lease pursuant to the option to extend set forth in the Existing 701 Lease (“Existing 701
Extension Option”); and (ii) Landlord’s right, which Landlord hereby reserves, from time to time
prior to May 12, 2010, to amend the Existing 701 Lease on such terms and conditions as are
acceptable to Landlord, in its sole discretion, including an extension amendment on terms and
conditions different from those set forth in the existing option to extend, provided however, in no
event shall any such amendment to the Existing 701 Lease extend the term beyond February 20, 2016,
extend the option term of the Existing 701 Extension Option to a term beyond February 20, 2016,
and/or grant any additional option to extend or renew.

     (b) Exercise:
Expansion Space; Expansion Demising Work. This Option shall be
exercisable only by Tenant giving Landlord within the Expansion Exercise Period (defined below)
irrevocable written notice (the “Expansion Exercise Notice”) of Tenant’s election to lease the 701
Galveston Expansion Space (defined below), subject to the terms and conditions set forth below.
Further, in the event that no later than the earlier of (x) thirty days before the date on which
the Expansion Exercise Period expires or (y) the date on which Tenant gives its Expansion Exercise
Notice, Tenant gives Landlord a written request to negotiate the terms and conditions of the lease
of the 701 Galveston Expansion Space (“Negotiation Notice”), then both Landlord and Tenant shall
negotiate in good faith the terms and conditions of the lease of the 701 Galveston Expansion Space
until the earlier of (xx) the date which is thirty days after Tenant gives the Negotiation Notice
or (yy) the date on which Tenant gives its Expansion Exercise Notice. “701 Galveston Expansion
Space” shall mean that space outlined on Exhibit I hereto, containing approximately 18,121
square feet of Rentable Area and located in the building at the address known as 701 Galveston
Drive, Redwood City, California 94063. The “Expansion Exercise Period” shall mean the period
starting May 21, 2010 and ending June 20, 2010, or if the Existing 701 Lease is extended in
accordance with Section 4(a)(i) or 4(a)(ii) above, then the “Expansion Exercise Period” shall mean
the period starting twelve (12) months before and ending nine (9) months before the scheduled
expiration date of the extended term of the Existing 701 Lease. Notwithstanding the foregoing:

     (i) Landlord shall not permit or agree to an extension of the term of the Existing 701
Lease, except as set forth in Section 4(a)(i) or 4(a)(ii) above or for a holdover of more
than one (1) month after the applicable, scheduled expiration date;

     (ii) in the event that Landlord recovers or will recover possession of the 701
Galveston Expansion Space early in connection with a bankruptcy, insolvency, abandonment or
other default on the part of the tenant under the Existing 701 Lease, or reasonable prospect
of any of the foregoing, then the Expansion Exercise Period shall instead be the period of
sixty (60) days after written notice from Landlord to Tenant stating the earlier projected
delivery date for the 701 Galveston Expansion Space, and if Landlord for any other reason
permits or agrees to a reduction of the term (or early termination) of the Existing 701
Lease, then the Expansion Exercise Period shall remain as set forth in the preceding
sentence of this Section 4(b); and

     (iii) if Tenant does not timely deliver to Landlord a valid Expansion Exercise Notice,
this Option shall terminate and be null and void.

     (c) Rent & Certain Terms of the Lease of the Expansion Space. If Tenant duly and
timely delivers its Expansion Exercise Notice to Landlord, such exercise shall thereby create and
constitute a binding lease of the 701 Galveston Expansion Space by and to Tenant, subject to
suspension or termination of such right pursuant to Subsection (e) below, upon and subject to the
same terms and conditions contained in the Lease with the following modifications:

     (i) Landlord shall give Tenant written notice (“Landlord’s Expansion Notice”) no later
than thirty (30) days after receipt of Tenant’s Expansion Exercise Notice, which notice
specifies the rentable area of the 701 Galveston Expansion Space (using Landlord’s then
applicable space measurement method in the 701 Galveston building), Landlord’s estimate of
the projected date such space will be vacant and deliverable to Tenant, required increase
in Security pursuant to Subsection (ix) below, Landlord’s estimate of the applicable Fair
Market Rental Rate, as defined in Exhibit F hereto (“Landlord’s Estimate”).
Landlord’s Estimate set forth in Landlord’s Expansion Notice shall be conclusive and
binding as the Monthly Base Rent payable for the 701 Galveston Expansion Space unless
Tenant notifies Landlord within ten (10) business days after Landlord gives Landlord’s
Expansion Notice that Tenant disputes Landlord’s Estimate and specifies in detail the
reasons therefor and states Tenant’s good

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faith estimate of the Fair Market Rental Rate (the “Expansion Rent Dispute Notice”). If the
dispute is not resolved within ten (10) business days after Landlord receives the Expansion Rent
Dispute Notice, then the Fair Market Rental Rate shall be determined in accordance with the terms
of Exhibit F;

     (ii) Tenant shall accept the 701 Galveston Expansion Space in its then “AS IS” condition, but
broom clean and free of all tenants or occupants, without any obligation of Landlord to repaint,
remodel, improve or alter such space for Tenant’s occupancy or to provide Tenant any allowance
therefor except to the extent tenants leasing space in Comparable Transactions (as defined in
Exhibit F hereto) receive an allowance pursuant to the definition of Fair Market Rental
Rate, provided, however, Landlord, in Landlord’s Expansion Notice, may elect to provide, in lieu
of such allowance for alterations to the 701 Galveston Expansion Space, a rent credit equal to the
amount of the allowance that otherwise would have been given, credited toward the rents applicable
only to the 701 Galveston Expansion Space and due starting after such rent obligation commences;

     (iii) subject to Subsection (b)(ii) above, Landlord shall deliver the 701 Galveston Expansion
Space to Tenant no later than thirty (30) days after Landlord recovers possession of such space,
and not sooner than thirty (30) days after Landlord gives written notice of the projected delivery
date, unless Tenant accepts early delivery. If Landlord receives any written correspondence or
notice from the existing tenant of the Expansion Space that indicates that such existing tenant may
be delayed in surrendering possession of the 701 Galveston Expansion Space, Landlord shall promptly
notify Tenant. If the existing tenant holds over in the 701 Galveston Expansion Space more than one
(1) month after the earlier of the scheduled expiration date of the Existing 701 Lease, as it may
be extended pursuant to Section 4(a)(i) or 4(a)(ii), or earlier termination date, Landlord shall
use commercially reasonable efforts to promptly recover possession of the Expansion Space. If
Landlord has not tendered possession of the 701 Galveston Expansion Space in the condition required
by this Lease on or before the Sunset Date (defined below), then, as Tenant’s sole and exclusive
remedy, Tenant shall have the option to terminate this Lease with respect to the 701 Galveston
Expansion Space upon written notice to Landlord within three (3) business days after the Sunset
Date. As used in this Lease, “Sunset Date” means the date that is six (6) months after the date of
the earlier of (x) the scheduled expiration date of the Existing 701 Lease, as it may be extended
pursuant to Section 4(a)(i) or 4(a)(ii), or (y) an earlier termination date;

     (iv) upon such delivery, the 701 Galveston Expansion Space shall be leased for the “701
Galveston Term”, which shall commence on such delivery date and expire on March 31, 2019 (the “701
Galveston Expiration Date”), which Landlord and Tenant acknowledge is different than the
Expiration Date of the Term for the Premises. Landlord and Tenant acknowledge and agree that the
Option to Extend in Section 5 below shall not apply to extend the 701 Galveston Term but that
Tenant shall have a separate and distinct 701 Galveston Extension Option to extend the 701
Galveston Term for a single five (5) year period on the same conditions and terms as set forth in
the Option to Extend in Section 5 below, provided however, notwithstanding anything to the
contrary in Section 5 below: (i) such 701 Galveston Extension Option shall be a single option to
extend the 701 Galveston Term of the 701 Galveston Expansion Space for a period of five (5) years
as to the entire 701 Galveston Expansion Space, and the phrase “701 Galveston Term” is inserted in
place of references to the “Term of the Lease” or “initial Term”, (ii) the phrase “701 Galveston
Expansion Space” is inserted in place of the phrase “Premises”, and (iii) Tenant’s election
(“Election Notice”) to exercise the 701 Galveston Extension Option must be given to Landlord in
writing during the period starting April 1, 2018 and ending June 30, 2018 (which the parties
acknowledge to be the period starting twelve (12) months before and ending nine (9) months before
the 701 Galveston Expiration Date).

     (v) the “Expansion Rent Commencement Date” shall be the earlier to occur of (x) one hundred
twenty (120) days after the 701 Galveston Expansion Space is delivered to Tenant, or (y) Tenant’s
occupancy of any part of the 701 Galveston Expansion Space for business purposes, and starting on
the Expansion Rent Commencement Date, Tenant shall pay Monthly Base Rent with respect to the 701
Galveston Expansion Space equal to the Fair Market Rental Rate (with Fair Market Rental Rate
defined and determined as set forth herein and in Exhibit F); provided, however, if the
Expansion Rent Commencement Date is the date in clause (x) above, then for the period, if any,
from and after the Expansion Rent Commencement Date and prior to and including the earlier of
February 20, 2011 or the date in clause (y) above, Tenant shall pay a reduced Monthly Base Rent
equal to fifty percent (50%) of the Fair Market Rental Rate;

     (vi) the 701 Galveston Lease (as defined below) shall provide that starting on the Expansion
Rent Commencement Date, with respect to the 701 Galveston Expansion Space Tenant shall pay
Tenant’s Share of Operating Expenses, as applicable and more particularly provided therein, with
“Tenant’s Share” calculated to reflect the 701 Galveston Expansion Space;

     (vii) the 701 Galveston Lease (as defined below) shall provide that starting on such delivery
date, Tenant shall pay other charges payable by Tenant for utilities and otherwise with respect to
the 701 Galveston Expansion Space;

     (viii) starting on the Expansion Rent Commencement Date, with respect to the 701 Galveston
Expansion Space Tenant shall additionally be entitled to rent the number of non-exclusive parking
spaces determined at the rate of 3.3 parking spaces per 1000 square feet of Rentable Area of the
701 Galveston Expansion Space; and

     (ix) the security under the 701 Galveston Lease (as defined below) shall be an amount equal
to the Fair Market Rental Rate for the final three (3) months of the term of the 701 Galveston
Lease.

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     (d) Promptly after final determination of the Fair Market Rental Rate, Landlord shall prepare
a separate lease for the 701 Galveston Expansion Space in accordance with the terms and conditions
of this Option, in substitution of an amendment of this Lease for the 701 Galveston Expansion
Space, but otherwise on the same terms and conditions as this Lease to the extent applicable to the
701 Galveston Expansion Space. Tenant and Landlord agree to execute such separate lease promptly
after it is prepared by Landlord and submitted to Tenant.

     (e) During any period that Tenant does not occupy the entire Premises or that there is an
uncured default by Tenant under the Lease, or any state of facts which with the passage of time or
the giving of notice, or both, would constitute such a default, this Option shall not apply and
shall be ineffective and suspended, and any notice by Tenant purportedly exercising this Option
shall be null and void, and Landlord shall not be obligated to proceed (or enter any amendment)
with respect to any 701 Galveston Expansion Space which was the subject of a notice of exercise by
Tenant for which an amendment has not been fully executed. This Option shall terminate, and be
null and void, if prior to execution of the 701 Galveston Lease by both Tenant and Landlord for the
lease of the 701 Galveston Expansion Space any of the following events occur: (1) the existence
of a default by Tenant under the Lease after any applicable notice and expiration of any applicable
time to cure; (2) the termination of the Lease upon the occurrence of a Tenant default or
otherwise; (3) Landlord’s recovery of possession of the Premises upon the occurrence of a Tenant
default or otherwise; (4) rejection of the Lease in any bankruptcy proceeding; or (5) the failure
of Tenant timely to give the Expansion Exercise Notice.

     (f) This Option is personal to Genomic and may not be used by, and shall not be transferable
or assignable (voluntarily or involuntarily) to any person or entity other than a Permitted
Transferee which is an assignee of the Lease and which has satisfied the requirements of Sections
10.01 and 10.05 of this Lease, and such Permitted Transferee may exercise the right without Tenant
joining in or consenting to such exercise, and notwithstanding anything to the contrary, Tenant
shall remain liable for all obligations under the Lease, including those resulting from any such
exercise with the same force and effect as if Tenant had joined in such exercise.

SECTION 5. OPTION TO EXTEND.

     (a) Landlord hereby grants Tenant a single option to extend the Term of the Lease for an
additional period of five (5) years (such period may be referred to as the “Option Term”), as to
the entire Premises, excluding the 701 Galveston Expansion Space (if leased pursuant to the 701
Galveston Expansion Option) for which a different lease term and extension option shall apply, upon
and subject to the terms and conditions of this Section (the “Option To Extend”), and provided that
at the time of exercise of such option (and each Option, if more than one Option is granted): (i)
Tenant or a Permitted Transferee which has satisfied the requirements of Sections 10.01 and 10.05
of the Lease must be conducting regular, active, ongoing business in, and be in occupancy (and
occupancy by a subtenant, licensee or other party permitted or suffered by Tenant shall not satisfy
such condition) of the entire Premises; and (ii) there has been no material adverse change in
Tenant’s financial position from such position as of the date of execution of the Lease, as
certified by Tenant’s independent certified public accountants, and as supported by Tenant’s
certified financial statements, copies of which shall be delivered to Landlord with Tenant’s
written notice exercising its right hereunder. Without limiting the generality of the foregoing,
Landlord may reasonably conclude there has been a material adverse change if Tenant’s independent
certified public accountants do not certify there has been no such change.

     (b) Tenant’s election (the “Election Notice”) to exercise the Option To Extend must be given
to Landlord in writing during the period starting twelve (12) months before and ending nine (9)
months before the scheduled Expiration Date of the initial Term. If Tenant either fails or elects
not to exercise the Option to Extend by not timely giving its Election Notice, then the Option to
Extend shall be null and void, including, if more than one Option is granted, the then applicable
Option to Extend and all further Options to Extend.

     (c) The Option Term (and each Option Term, if more than one Option is granted) shall commence
immediately after the expiration of the preceding Term of the Lease. Tenant’s leasing of the
initial Premises and Expansion Space during the Option Term shall be upon and subject to the same
terms and conditions contained in the Lease except that (i) Tenant shall pay the “Option Term
Rent”, defined and determined in the manner set forth in the immediately following Subsection; (ii)
the Security shall be increased to an amount that is the same percentage or proportion of Option
Term Rent as the prior amount of Security was in relation to Rent for the Term prior to the Option
Term, but in no event shall the Security be decreased; and (iii) Tenant shall accept the initial
Premises and Expansion Space in its “as is” condition without any obligation of Landlord to
repaint, remodel, repair, improve or alter the initial Premises and Expansion Space or to provide
Tenant any allowance therefor, except to the extent tenants leasing space in Comparable
Transactions receive an allowance pursuant to the definition of Fair Market Rental Rate defined in
Exhibit F hereto, provided, however, Landlord by notice given to Tenant within thirty (30)
days after final determination of the Fair Market Rental Rate, may elect to provide, in lieu of
such allowance for alterations to the initial Premises and Expansion Space, a rent credit equal to
the amount of the allowance that would have otherwise been given, credited toward the rents
applicable only to the Initial Premises and Expansion Space and due starting after such rent
obligation commences. If Tenant timely and properly exercises the Option To Extend, references in
the Lease to the Term shall be deemed to mean the preceding Term as extended by the Option Term
unless the context clearly requires otherwise.

     (d) The Option Term Rent shall mean the sum of the Monthly Base Rent at the Fair Market Rental
Rate (as defined in Exhibit F) plus Rent Adjustments and/or certain Operating Expenses (if
applicable, based upon a step-up to change the base year or base amount for calculation of
Operating Expenses in connection with determination of the Fair Market Rental Rate) plus other
charges pursuant to the Lease payable to Landlord. The determination of Fair Market Rental Rate
and Option Term Rent shall be made by Landlord, in the good faith exercise of Landlord’s business
judgment. Within forty-five (45) days after Tenant’s exercise of the Option To Extend, Landlord
shall notify Tenant of Landlord’s determination of the Fair Market Rental Rate

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and Option Term Rent for the initial Premises and Expansion Space. Tenant may, within fifteen (15)
days after receipt thereof, deliver to Landlord a written notice either: (i) accepting Landlord’s
determination, in which case the extension shall be effective and binding (subject to Subsection
(f) below) at the accepted rate; or (ii) setting forth Tenant’s good faith estimate, in which case
Landlord and Tenant will promptly confer and attempt to agree upon the Fair Market Rental Rate and
Option Term Rent. Tenant’s failure to timely deliver such notice within such fifteen (15) day
period shall be deemed its cancellation of the Option. In the event Tenant has delivered notice
setting forth Tenant’s different estimate, but no agreement in writing between Tenant and Landlord
on Fair Market Rental Rate and Option Term Rent is reached within thirty (30) days after Landlord’s
receipt of Tenant’s estimate, the Fair Market Rental Rate shall be determined in accordance with
the terms of Exhibit F. Notwithstanding any of the foregoing to the contrary, at no time during the
Option Term shall the Option Term Rent be less than the “Preceding Rent” (defined below). The
Preceding Rent shall mean the sum of the Monthly Base Rent payable by Tenant under this Lease
calculated at the rate applicable for the last full month of the Term preceding the Option Term
plus the Rent Adjustments payable by Tenant under the Lease (if applicable, using the base year for
calculation of Base Operating Expenses applicable for the last full month of the Term preceding the
Option Term), plus other charges pursuant to the Lease payable to Landlord. To the extent that
Tenant pays directly the utility or service provider for utilities or services which Tenant is to
obtain directly pursuant to the Lease, Tenant shall continue to pay such amounts, but such amounts
shall not be counted as part of the Preceding Rent or the Fair Market Rental Rate as used herein.
Further, in the event that Landlord notifies Tenant that the Option Term Rent shall equal the
Preceding Rent, such determination shall be conclusive and binding to set the Preceding Rent as the
Option Term Rent for the Option Term, Tenant shall not be entitled to dispute or contest such
determination, and the extension shall be effective and binding (subject to Subsection (f) below).

     (e) Promptly after final determination of the Fair Market Rental Rate, Landlord shall prepare
a memorandum confirming the specific dates, amounts and terms of the extension for the Option Term
in accordance with the terms and conditions of this Option to Extend, in the form of an amendment
to the Lease, and Tenant shall execute such amendment within five (5) business days after Landlord
and Tenant agree to the form of the proposed amendment and Landlord shall execute it promptly after
Tenant. Notwithstanding any of the foregoing to the contrary, the failure of Landlord to prepare
such amendment or of either party to execute an amendment shall not affect the validity and
effectiveness of the extension for the Option Term in accordance with the terms and conditions of
this Option to Extend.

     (f) Upon the occurrence of any of the following events, Landlord shall have the option,
exercisable at any time prior to commencement of the Option Term, to terminate all of the
provisions of this Section with respect to the Option to Extend, whereupon any prior or subsequent
exercise of this Option to Extend shall be of no force or effect:

     (i) Tenant’s failure to timely exercise or timely to perform the Option to Extend in
strict accordance with the provisions of this Section.

     (ii) The existence at the time Tenant exercises the Option to Extend or at the
commencement of the Option Term of a Default on the part of Tenant under the Lease or of
any state of facts which with the passage of time or the giving of notice, or both, would
constitute such a Default.

     (iii) Tenant’s third Default under the Lease prior to the commencement of the Option
Term, notwithstanding that all such Defaults may subsequently be cured.

     (g) Without limiting the generality of any provision of the Lease, time shall be of the
essence with respect to all of the provisions of this Section.

     (h) This Option to Extend is personal to Genomic and may not be used by, and shall not be
transferable or assignable (voluntarily or involuntarily) to any person or entity other than a
Permitted Transferee which is an assignee of the Lease and which has satisfied the requirements of
Sections 10.01 and 10.05 of this Lease, and such Permitted Transferee may exercise the right
without Tenant joining in or consenting to such exercise, and notwithstanding anything to the
contrary, Tenant shall remain liable for all obligations under the Lease, including those
resulting from any such exercise with the same force and effect as if Tenant had joined in such
exercise.

Rider 2 - Page 5

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