Document:

EXHIBIT 10.52
                               FIRST AMENDMENT TO
                          LICENSE AND ROYALTY AGREEMENT

         This First Amendment To License and Royalty Agreement ("Amendment"), is
made and entered into as of January 18, 2000 (the "Amendment Date"), by and
among LASERSIGHT TECHNOLOGIES, INC., a Delaware corporation ("Licensee"), LUIS
A. RUIZ, M.D. and SERGIO LENCHIG (collectively, the "Licensors").

         WHEREAS,  the  Licensors  and  Licensee  have entered into that certain
License and Royalty Agreement dated as of September 10, 1997 (the "Agreement");

         WHEREAS,  the Licensors  and Licensee  desire to amend certain terms of
the Agreement as provided herein with certain amendments being conditioned on
the occurrence of future events; and

         WHEREAS, LaserSight Incorporated,  a  Delaware  corporation
("LaserSight"), has agreed to guaranty certain obligations of Licensee.

         NOW, THEREFORE,  for and in  consideration  of the mutual promises and
valuable  consideration  set forth herein,  the parties hereto mutually agree as
follows:

         1.   Amendments to Agreement Effective Immediately.  As of the
              ---------------------------------------------
Amendment Date the Agreement shall be revised as follows:

              1.1   Section 1(b) of the Agreement.  Section 1(b) of the
                    -----------------------------
         Agreement is deleted in its entirety.

              1.2   Section 2.  Section 2 of the Agreement shall be deleted in
                    ---------
         its entirety and replaced with the following:

              2.    Term.  This  Agreement  shall be  effective  as of the date
                    ----
              first set forth above (the "Effective Date"), and shall
              commence on January 1, 2000 (the "Commencement Date"), and
              shall continue thereafter until July 31, 2002 (the "Initial
              Term"), unless earlier terminated as provided herein. At the
              conclusion of the Initial Term Licensee shall have the sole
              option to renew this Agreement for additional one (1) year
              terms (each a "Renewal Term" and collectively "Renewal Terms",
              and the Initial Term together with the Renewal Terms shall
              constitute the "Term") upon the terms and conditions as set
              forth herein; provided, however, with respect to Licensee's
              obligations pursuant to Section 5 of this Agreement during the
              Renewal Term(s), Licensee shall be obligated to pay to
              Licensors only the payments described in Sections 5(a)(v) and
              5(e).

              1.3   Section 4(f).  Section 4(f) of the Agreement shall be
                    ------------
         deleted in its entirety.

<PAGE>
              1.4   Section 5(a) of the Agreement.  The following new Section
                    -----------------------------
         5(a)(vi) shall be insertedinto the Agreement:

              (vi)  $200,000 U.S. upon Licensee's receipt of a completely
              executed copy of the Amendment, and    $200,000 U.S. on April 1,
              2000 (such payments shall be referred to herein as the "Advanced
              Payments").

              1.5   Section 5(b) of the Agreement. Section 5(b) of the Agreement
                           -----------------------------
         is deleted in its entirety and the following inserted in its place:

              (b)   [INTENTIONALLY LEFT BLANK]

              1.6   Section 5(c)(iii) of the Agreement.  Section 5(c)(iii) of
                    ----------------------------------
         the Agreement shall be deleted in its entirety and replaced with the
         following:

              (iii) for purposes of  determining  Gross Profit,  all amounts
              invoiced by Licensee or LaserSight shall be included which are
              the result of sales of Covered Products (as defined herein)
              and other components which are related to the Covered Products
              including, but not limited to, (A) disposable or reusable
              microkeratome with gear box, suction ring, and suction handle,
              (B) motor, (C) motor power cord, (D) tonometer, (E) suction
              and power supply, (F) foot switch, (G) tubing, (H) user's
              manual, (I) sterile packaging, (J) control consoles, (K)
              blades, (L) replacement parts, (M) lid speculum, and other
              component parts which are manufactured utilizing the Licensed
              Patents and/or the Licensed Technology (collectively, the
              "Products"). For purposes of this Section 5(c)(iii), the term
              "Covered Products" shall mean Licensee's UniShaperTM keratome,
              UltraShaperTM keratome and any other keratome manufactured,
              distributed or sold by Licensee or LaserSight.

              1.7   Section 5(e) of the  Agreement.  The phrase "the date that
                    ------------------------------
         is seven (7) months after the Commencement Date" that appears in lines
         one and two of Section 5(e) of the Agreement shall be deleted and
         replaced with the following: "July 1, 2000".

              1.8   Section 17 of the Agreement.  Section 17 of the Agreement is
                    ---------------------------
         hereby deleted in itsentirety and replaced with the following:

              17.   Additional Obligations.  Nothing contained in the Agreement
                           ----------------------
              or the Amendment shall be    construed to prohibit Licensee from
              manufacturing, distributing, marketing, promoting in any
              manner, or selling any keratome, whether or not such keratome is
              covered by claims of the    Licensed Patents or Licensed
              Technology.

              1.9   Section 18 of the Agreement.  Section 18 of the Agreement
                    ---------------------------
         is hereby deleted in itsentirety and replaced with the following:

<PAGE>

              18.  Mold Use and  Manufacture.  Licensors  agree  to  provide
                   -------------------------
              Licensee with single cavity limited production molds ("Limited
              Production Molds") capable of producing disposable
              microkeratomes which are safe and effective for their intended
              use. Licensors and Licensee shall share equally in the cost of
              manufacturing the Limited Production Molds. In the event the
              Limited Production Molds need to be replaced, as determined by
              the manufacturer thereof, Licensors and Licensee shall share
              equally in the cost of such replacement.

              The Licensee shall be solely responsible for the design,
              manufacture, engineering, tooling and testing of the dual
              cavity, automatic production molds (the "Final Production
              Molds") capable of producing disposable microkeratomes which
              are safe and effective for their intended use and shall pay
              the entire cost thereof, including all unpaid amounts
              currently owed therefor. In the event the Final Production
              Molds need to be replaced, as determined by the manufacturer
              thereof, Licensee shall be solely responsible for the cost of
              such replacement.

              The Licensors acknowledge and agree that the Final Production
              Molds shall be the sole and exclusive property of Licensee.
              After the Termination Date (as defined in the Agreement)
              Licensee agrees to entertain any reasonable offer from
              Licensors for the purchase of the Final Production Molds. If,
              after the Termination Date, Licensee receives a bona fide
              offer from a licensee of the Licensed Patents or the Licensed
              Technology for the purchase of the Final Production Molds (the
              "Offer"), Licensee shall notify Licensors of the existence and
              terms and conditions of the Offer. Licensors shall have ten
              (10) days after receipt of such notice from Licensee to notify
              Licensee that Licensors desire to purchase the Final
              Production Molds on the same terms and conditions as set forth
              in the Offer. If Licensors fail to notify Licensee within said
              ten (10) day period, Licensors shall be deemed to have elected
              not to exercise its option hereunder. Licensee shall then be
              free to accept the Offer, but only from such prospective
              purchaser and in strict accordance with the terms and
              conditions of the Offer. In no event and under no
              circumstances shall Licensee or LaserSight sell or transfer
              the Final Production Molds to any person or entity to whom or
              which Licensors have not granted a license to the Licensed
              Patents or Licensed Technology.

              1.10  Section 19 of the Agreement.  Section 19 of the Agreement is
                    ---------------------------
         hereby deleted in its entirety and replaced with the following:

              19.   Return of Molds.  Within fifteen (15) days following the
                    ---------------
              Termination Date, Licenseeshall return the Limited Production
              Molds to Licensors.
<PAGE>

              1.11 Section 21 of the  Agreement.  The  parenthetical  phrase
         "(other than claims arising in connection with the design, engineering,
         and/or the specifications of the Devices delivered pursuant to Section
         4(f))" that appears in lines 4, 5 and 6 of Section 21 of the Agreement
         is hereby deleted.

         2.   Royalty Shares.
              --------------

              2.1   Issuance  of  Royalty  Shares.  On  the  Amendment  Date,
                    -----------------------------
         LaserSight shall send its transfer agent an irrevocable letter of
         direction to issue four stock certificates (two in the name of each
         Licensor) each representing that number of shares of common stock,
         $.001 par value per share ("Common Stock") which shall be determined by
         dividing (i) $1,250,000, by (ii) the closing price of Common Stock as
         quoted on the Nasdaq National Market (the "NASDAQ") for the trading day
         immediately preceding the Amendment Date. The certificates representing
         the shares of Common Stock issued in accordance with this Section 2.1
         shall be referred to as the "Royalty Shares". Also on the Amendment
         Date Licensors shall execute stock powers, in form and substance
         satisfactory to LaserSight, providing for the transfer of the Royalty
         Shares to LaserSight.

              2.2   Escrow of Royalty Shares. The Royalty Shares and the Stock
                    ------------------------
         Powers shall be delivered to and held in escrow by LaserSight. The
         parties acknowledge and agree that during the period the Royalty
         Shares, or any part thereof, are being held in escrow, the Licensors
         will be entitled to (i) exercise any and all voting and other
         consensual rights pertaining to the Royalty Shares or any part thereof,
         and (ii) receive and retain any and all dividends and other
         distributions paid in respect of the Royalty Shares. The Royalty Shares
         shall be released from escrow to the Licensors in accordance with the
         terms of Section 3. However, if the Royalty Shares are not released
         from escrow to the Licensors in accordance with the terms of Section 3,
         the Royalty Shares shall be released from escrow to LaserSight, and
         LaserSight is hereby directed to utilize the Stock Powers in order to
         transfer the ownership of the Royalty Shares from Licensors to
         LaserSight.

              2.3   Restricted Shares. The Licensors  acknowledge and
                    -----------------
         agree that the Royalty Shares (i) are authorized but previously
         unissued Common Stock which have not been registered under the
         Securities Act of 1933, as amended ("the Act"), or any state securities
         laws, (ii) have been acquired for investment purposes only and not with
         a view to distribution or resale, (iii) may not be sold or transferred
         unless such shares have been registered under the Act and such
         applicable state securities laws, or unless in the opinion of counsel
         acceptable to LaserSight an exemption from registration is available,
         and (iv) the certificates representing such shares shall bear
         substantially the following legend:

           THE SHARES OF COMMON STOCK REPRESENTED BY THIS CERTIFICATE
           HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS
           AMENDED (THE "ACT"), OR ANY APPLICABLE STATE SECURITIES LAW

<PAGE>

           AND MAY NOT BE TRANSFERRED UNTIL (I) A REGISTRATION STATEMENT
           UNDER THE ACT AND SUCH APPLICABLE STATE SECURITIES LAWS SHALL
           HAVE BECOME EFFECTIVE WITH REGARD THERETO, OR (II) IN THE
           OPINION OF COUNSEL ACCEPTABLE TO THE COMPANY, REGISTRATION
           UNDER SUCH SECURITIES ACTS AND SUCH APPLICABLE STATE
           SECURITIES LAWS IS NOT REQUIRED IN CONNECTION WITH SUCH
           PROPOSED TRANSFER.

         The Royalty Shares have those registration rights that are more fully
         described in that certain Registration Rights Agreement, dated as of
         the Amendment Date, substantially in the form which is attached hereto
         as Exhibit A.

         3.   Amendments to Agreement Effective Upon Certain Events. If (i)
during the  period  commencing  on the  Amendment  Date and  ending on April 30,
2000, LaserSight  raises at least  $15,000,000  in  proceeds  (the  "Capital
Target") through the sale of LaserSight  Common Stock; or (ii) Licensee,  in its
sole and absolute discretion,  elects to make the Initial Payment (as defined
below) even though  the  Capital  Target  has not been  achieved  (provided,
however,  such election must be made by Licensee and  communicated  to the
Licensors  prior to April 30, 2000), then the amendments to the Agreement set
forth in Sections 3.1, 3.2,  3.3, 3.4, 3.5 and 3.6 below shall become  effective
and Licensee  shall be obligated  to make the  payments  described  in Sections
3.1,  3.2, 3.3 and 3.4 below.  LaserSight  acknowledges and agrees that it will
use its reasonable best efforts to reach the Capital Target on or prior to
April 30, 2000.

              3.1   Sections 5(a)(i) and 5(a)(iii) of the Agreement.  The
                    -----------------------------------------------
         following sentence shall be added at the end of each of Section 5(a)(i)
         and 5(a)(iii):  "The previous receipt of which is herebyacknowledged."

              3.2   Section 5(a)(ii) of the Agreement. Section 5(a)(ii) of the
                    ---------------------------------
         Agreement shall be deleted in its entirety and replaced with the
         following:

              (ii)  Within five business days after the earlier of the date on
                    which the Capital Target is achieved, or the date on which
                    Licensee has communicated to the Licensors its decision to
                    make the election described in phrase (ii) of the
                    first sentence of Section 3 of the Amendment, Licensee shall
                    (i) wire transfer $4,000,000 U.S. (less the amount of any
                    Advanced Payments made as of the date of such payment) in
                    immediately available funds to the Licensors in accordance
                    with wire transfer instructions provided to Licensee by the
                    Licensors (the "Initial Payment"), and (ii) direct
                    LaserSight to release a certificate to each of the Licensors
                    representing, in the aggregate, one-half (1/2) of the
                    Royalty Shares.
<PAGE>

                    Notwithstanding the provisions of Section 5(a)(vi), if all
                    or any portion of the Advanced Payments have not been made
                    at the time the Initial Payment is made, then once the
                    Initial Payment is made Licensee shall have no further
                    obligation to make the Advanced Payments (or unpaid portion
                    thereof).

              3.3   Section 5(a)(iv) of the Agreement. Section 5(a)(iv) of the
                    ---------------------------------
         Agreement shall be deletedin its entirety and replaced with the
         following:

                    (ii)  Within   five   business   days   after  the six-month
                          anniversary of the Amendment Date, Licensee shall (i)
                          wire transfer $2,000,000 U.S. in immediately available
                          funds to the Licensors in accordance with wire
                          transfer instructions provided to Licensee by the
                          Licensors, and (ii) direct LaserSight to release a
                          certificate to each of the Licensors representing, in
                          the aggregate, the remaining one-half (1/2) of the
                          Royalty Shares.

                          In addition, within five business days after the
                          nine-month anniversary of the Amendment Date, Licensee
                          shall wire transfer $2,000,000 U.S. in immediately
                          available funds to the Licensors in accordance with
                          wire transfer instructions provided Licensee by the
                          Licensors.

              3.4   Section 5(a)(v) of the Agreement.  During the Initial Term
                    --------------------------------
         only, Section 5(a)(v) of the Agreement shall be deleted in its entirety
         and replaced with the following:

                    (v)   ten percent  (10%) of the Gross  Profits (as
                          defined in Section 5(a) of the Agreement, as
                          such Section has been revised by the
                          Amendment) ("Gross Profit Payment") shall be
                          paid to the Licensors no later than
                          forty-five (45) days after the end of each
                          calendar quarter during the Term.

              Following  the Initial Term and during any Renewal  Term,  the
         first of which would commence August 1, 2002, if the Agreement is
         renewed by Licensee, the payments to Licensors shall be made in
         accordance with Section 5(a)(v) of the Agreement (as such Section
         existed prior to the amendment contemplated by this Section 3.4), which
         Section 5(a)(v) shall be deemed reinstated following the Initial Term
         and during any Renewal Term.

              3.5   Sections  5(e)  and  5(f) of the  Agreement.  During  the
                    -------------------------------------------
         Initial Term only, Sections 5(e) and 5(f) of the Agreement shall be
         deemed deleted in their entirety. Following the Initial Term and during
         any Renewal Term, the first of which would commence August 1, 2002, if

<PAGE>

         the Agreement is renewed by Licensee, Sections 5(e) and 5(f) of the
         Agreement shall be deemed reinstated following the Initial Term and
         during any Renewal Term.

              3.6   Section 20 of the Agreement. During the Initial Term only,
                    ---------------------------
         the words "Minimum Payment Requirement" that appear in line 10 of this
         Section shall be deemed deleted and replaced with the words "Gross
         Profit Payment."

              3.7   Amendments Not Effective in Certain Circumstances.
                    -------------------------------------------------
         If neither of the events described in the first sentence of Section 3
         occurs on or prior to April 30, 2000, then (i) amendments contemplated
         by this Section 3 shall not become effective and shall be of no further
         force or effect, (ii) the terms and conditions of the Agreement (as
         amended by Section 1 of this Amendment) will remain in full force and
         effect, and (iii) LaserSight shall remove the Royalty Shares from
         escrow and utilize the Stock Powers to transfer the Royalty Shares to
         LaserSight.

         4.   No Other Changes.  Except as specifically set forth herein, all
              ----------------
other terms and conditions of the Agreement shall remain in effect as originally
set forth therein.

         5.   Counterparts.  This Amendment may be executed in one or more
              ------------
counterparts, each of which shall be deemed an original and all of which shall
be deemed one and the same instrument.

         6.   Governing  Law.  The  validity,  formulation,   interpretation
              --------------
and performance of this Amendment shall be governed by the laws of the State of
Virginia, without giving effect to choice of law principles. The parties do
hereby irrevocably submit themselves to the personal jurisdiction of the United
States Federal Court for the Eastern District of Virginia and do hereby
irrevocably agree to service of such court's process upon them, and with respect
to the Licensors, on their counsel, Allan S. Buffenstein of Mezzullo &
McCandlish, so long as they remain counsel to the Licensors and thereafter until
such time as it is verified to Licensee in writing that the Licensors' successor
counsel has agreed to accept such service on the Licensors' behalf.

         7.   Outside Date for Execution of Amendment.  Unless this  Amendment
              ---------------------------------------
has been duly authorized and executed by Licensee and LaserSight and submitted
to Licensors for signature by 5:00 o'clock P.M. Richmond, Virginia time, on
January 18, 2000, this Amendment shall be of no effect and the Agreement shall
remain in effect as it presently exists, without this Amendment.

                  [Remainder of Page Intentionally Left Blank]

<PAGE>

         IN WITNESS  WHEREOF,  the  parties  hereto,  by their  respective  duly
authorized  officers,  have executed this Amendment as of the date first written
above.

LICENSORS:                                  LUIS A. RUIZ, M.D.

                                            /s/Luis A. Ruiz, M.D.
                                            ------------------------------------
                                            Luis A. Ruiz, M.D.

                                            SERGIO LENCHIG

                                            /s/Sergio Lenchig
                                            ------------------------------------
                                            Sergio Lenchig

LICENSEE:                                   LASERSIGHT TECHNOLOGIES, INC.

                                            By:  /s/Michael R. Farris
                                                --------------------------------
                                                 Michael R. Farris
                                                 President

         The undersigned  hereby  unconditionally  guarantees the payment of the
sums described in Section 2 of this Amendment as and when such sums become due
and payable according to the terms thereof. In case of failure of Licensee to
pay the obligations guaranteed hereby, the undersigned agrees to cause such
payment to be made as and when the same shall become due and payable, in the
manner specified in this Amendment and as if such payment were made by Licensee.
The undersigned agrees to those terms of the Agreement as amended by this
Amendment which pertain to the performance by the undersigned. This is a
guarantee of payment, not of collection.

                                            LaserSight Incorporated

                                            By:  /s/Michael R. Farris
                                                --------------------------------
                                                 Michael R. Farris
                                                 President and CEOEXHIBIT 10.53
                          REGISTRATION RIGHTS AGREEMENT

         This REGISTRATION RIGHTS AGREEMENT  ("Agreement") is made as of January
18, 2000, by and among LaserSight Incorporated, a Delaware corporation (the
"Company"), with headquarters located at 3300 University Boulevard, Suite 140,
Winter Park, Florida 32792, and Luis A. Ruiz, M.D. and Sergio Lenchig
(collectively, "Licensors"), with regard to the following:

                                    RECITALS

         A.   In  connection  with the First  Amendment  to  License  and
Royalty Agreement dated of even date herewith by and among the LaserSight
Technologies, Inc., a wholly owned subsidiary of the Company, and Licensors (the
"Amendment"), the Company has agreed, upon the terms and subject to the
conditions contained therein, to issue to Licensors shares of the Company's
common stock, par value $.001 per share (the "Common Stock"). The shares of
Common Stock to be issued to Licensors under the License Agreement shall be
referred to herein as the "Securities".

         B.   To induce  Licensors  to execute  and  deliver  the  Amendment,
the Company has agreed to provide to Licensors certain rights to a registration
of the Securities by the Company under the Securities Act of 1933 and the rules
and regulations thereunder, or any similar successor statute (collectively, the
"Securities Act"), and applicable state securities laws.

                                   AGREEMENTS

         In  consideration  of the mutual  covenants  contained herein and other
good and valuable consideration, the receipt and sufficiency of which are hereby
acknowledged, the Company and Licensors agree as follows:

1.       DEFINITIONS

         As used in this Agreement,  the following terms shall have the meanings
specified:

         Advice:  See Section 4 hereof.
         ------

         Agreement:  See the introductory paragraphs hereto.
         ---------

         Amendment:  See the introductory paragraphs hereto.
         ---------

         Blackout Event means a  determination  by the Board made in good faith,
         --------------
after consulting with outside securities counsel, that the registration of
Registrable Securities under the Securities Act or the continuation of the
disposition of Registrable Securities pursuant to an effective Piggy-Back
Registration Statement at such time (i) would have a material adverse effect
upon a proposed material sale of all (or substantially all) of the assets of the
Company or a material merger, reorganization, recapitalization or similar
current transaction materially affecting the capital structure or equity
ownership of the Company, or (ii) would require the Company to make a public
disclosure of information, which disclosure would have a material adverse effect
on the Company.

<PAGE>

         Blackout Period:  See Section 3(a) hereof.
         ---------------

         Board:  The Board of Directors of the Company.
         -----

         Claim:  See Section 6(a) hereof.
         -----

         Common Stock:  See the introductory paragraphs hereto.
         ------------

         Company:  See the introductory paragraphs hereto.
         -------

         Exchange Act:  The Securities Exchange Act of 1934 and the rules and
         ------------
regulations of the SEC promulgated thereunder.

         Form S-3: Form S-3 of the SEC under the Securities Act or any successor
         --------
form.

         Holdback Period:  See Section 3(b) hereof.
         ---------------

         Holder:  Any registered holder of a Registrable Security or Registrable
         ------
Securities, including, without limitation, the Licensors (and any of Licensors'
assignees).

         Indemnified Person:  See Section 6(c) hereof.
         ------------------

         Indemnifying Person:  See Section 6(c) hereof.
         -------------------

         Licensors: See the introductory paragraphs hereto.
         ---------

         Losses:  See Section 6(a) hereof.
         ------

         NASD:  See Section 4(j) hereof.
         ----

         Other Holders:  See Section 2(a) hereof.
         -------------

         Other Shares:  See Section 2(a) hereof.
         ------------

         Other Investors:  Any holder of equity securities of the Company or any
securities convertible into or exercisable or exchangeable for such equity
securities, which holder is entitled by written agreement with the Company to
have some or all of such securities included in a Piggy-Back Registration
Statement.

         Participant:  See Section 6(a) hereof.
         -----------

         Person:  An  individual,  trustee,  corporation,  partnership,  limited
         ------
liability company, trust, unincorporated association, business association, firm
or other legal entity.

<PAGE>

         Piggy-Back Registration Statement:  See Section 2(a) hereof.
         ---------------------------------

         Prospectus:  The  prospectus  included in any  Piggy-Back  Registration
         ----------
Statement (including, without limitation, any prospectus subject to completion
and a prospectus that includes any information previously omitted from a
prospectus filed as part of an effective registration statement in reliance upon
Rule 430A promulgated under the Securities Act), as amended or supplemented by
any prospectus supplement, and all other amendments and supplements to the
Prospectus, including post-effective amendments, and all material incorporated
by reference or deemed to be incorporated by reference in such Prospectus.

         Registrable  Securities  means  any  of  the  Securities.   As  to  any
         -----------------------
particular Registrable Securities held by a Holder, such securities shall cease
to be Registrable Securities when (i) a Piggy-Back Registration Statement with
respect to the offering of such securities by the Holder thereof shall have been
declared effective under the Securities Act and such securities shall have been
disposed of by such Holder pursuant to such Piggy-Back Registration Statement,
(ii) such securities may at the time of determination be sold to the public
pursuant to Rule 144 without any restriction on the amount of securities which
may be sold by such Holder without the lapse of any further time or the
satisfaction of any condition, or (iii) such securities shall have been
otherwise transferred by such Holder and new certificates for such securities
not bearing a legend restricting further transfer shall have been delivered by
the Company or its transfer agent, and subsequent disposition of such securities
shall not require registration or qualification under the Securities Act or any
similar state law.

         Registration Expenses:  See Section 5(b) hereof.
         ---------------------

         Registration Period:  See Section 2(c) hereof.
         -------------------

         Registration Statement: Any registration statement of the Company filed
         ----------------------
with the SEC under the Securities Act, including the Prospectus, all amendments
and supplements to such registration statement, post-effective amendments, all
exhibits, and all material incorporated by reference or deemed to be
incorporated by reference in such registration statement.

         Requested Shares:  See Section 2(a) hereof.
         ----------------

         Rule 144: Rule 144  promulgated  under the Securities Act, as such Rule
         --------
may be amended from time to time, or any similar rule or regulation hereafter
adopted by the SEC providing for public offers and sales of securities made in
compliance therewith resulting in offers and sales by subsequent holders that
are not affiliates of an issuer of such securities being free of the
registration and prospectus delivery requirements of the Securities Act.

         Rule 415: Rule 415  promulgated  under the Securities Act, as such Rule
         --------
may be amended from time to time, or any similar rule or regulation hereafter
adopted by the SEC.

<PAGE>

         SEC:  The Securities and Exchange Commission or any successor federal
         ---
agency charged with the enforcement of the federal securities laws.

         Securities Act: See the introductory paragraphs hereto.
         --------------

         Subsidiary:  Any  corporation  of which  the  Company  owns  securities
         ----------
representing a majority of the outstanding voting power or any partnership of
which the Company (or a Subsidiary) holds a majority of the general partner
interest.

         Underwritten  Offering:  A public  offering of Common  Stock,  or other
         ----------------------
securities convertible into, or exercisable or exchangeable for, Common Stock
that is underwritten on a firm commitment basis; provided that such offering
shall be exclusively for the account of any one or more of the Company or
Licensors (or any of Licensors' assignees).

2.       PIGGY-BACK REGISTRATION RIGHTS

         (a)  If during the  Registration  Period (as defined herein) the
Company proposes or is required to file with the SEC a registration statement
under the Securities Act relating to any shares of Common Stock (other than a
registration statement on Form S-8 or Form S-4 or any successor forms thereto,
or any other registration statement that does not permit the inclusion therein
of the Registrable Securities) (the "Piggy-Back Registration Statement"), the
Company will each such time give prompt written notice of its intention to do so
to each Holder. Upon the written request of any Holder given within 10 days
after the delivery or mailing of such notice from the Company, the Company will
use commercially reasonable efforts to include in such Piggy-Back Registration
Statement that number of the Securities specified by Holder in such written
request (subject to the limitations set forth in this Section 2(a) and in
Section 2(b) below) (the "Requested Shares") so as to permit the public sale of
such Requested Shares, provided that if the managing underwriter or underwriters
advise the Company that marketing factors require a limit on the number of
shares to be underwritten, the Company may (subject to the limitations set forth
below) exclude all Requested Shares from, or limit the number of Requested
Shares to be included in, the Piggy-Back Registration Statement and
underwriting. In such event, the Company shall so advise each requesting Holder,
and the number of Requested Shares and other shares ("Other Shares") requested
to be included in such Piggy-Back Registration Statement and underwriting by
other persons or entities that are then stockholders of the Company ("Other
Holders"), after providing for all shares that the Company proposes to offer and
sell for its own account, shall be allocated among the Requesting Holders and
Other Holders pro rata on the basis of (i) the number of Requested Shares then
held by the requesting Holders, and (ii) the aggregate number of Other Shares
then held by Other Holders.

         (b)  The right of any Holder to registration  shall be conditioned
upon (i) such Holder's execution of the underwriting agreement agreed to among
the Company and the managing underwriters selected by the Company for such
underwritten offering, (ii) such Holder's completion and execution of all
customary questionnaires and other documents which must be executed in
connection with such underwriting agreement, and (iii) such Holder supplying the

<PAGE>

Company and the underwriter such additional information as may be necessary to
register such Holder's Registrable Securities.

         (c)  The  registration  rights granted pursuant to this Section 2,
shall commence on July 15, 2000 and continue until the first to occur of (i) the
date on which all of the Securities have been sold by the Holders, and (ii) the
date on which all of the Securities may be immediately sold to the public
without registration conditions or limitations, whether pursuant to Rule 144 or
otherwise. The period of time commencing on July 15, 2000 and ending on the
earliest of the dates described in items (i) and (ii) of this Section 2(c) shall
be referred to as the "Registration Period".

3.       BLACKOUT AND HOLDBACK EVENTS

         (a)  During  any  period  of up  to 90  days'  duration  following  the
occurrence of a Blackout Event (a "Blackout Period"), the Company shall not be
required to file, or cause to be declared effective, under the Securities Act
any Piggy-Back Registration Statement hereunder, or, if applicable, the Holders
will discontinue the offer and sale of Registrable Securities pursuant to the
Piggy-Back Registration Statement.

         (b)  The Holders shall not, if requested by the managing  underwriter
or underwriters of an Underwritten Offering, effect any public or private sale
of any Common Stock, including a sale pursuant to Rule 144, during the period
("Holdback Period") beginning 14 days prior to, and ending 90 days after, the
effective date of the registration statement relating to such Underwritten
Offering.

         (c)  The  Company  shall  promptly  notify the Holders in writing of
any decision  not to file a  Piggy-Back  Registration  Statement  or not to
cause a Piggy-Back  Registration  Statement to be declared  effective or to
discontinue sales of Registrable  Securities  pursuant to this Section 3, which
notice shall set forth  the  reason  for such  decision  (but not  disclosing
any  nonpublic material  information)  and shall include an undertaking by the
Company promptly to notify the Holders as soon as sales may resume.

4.       REGISTRATION PROCEDURES

         In connection with the filing of a Piggy-Back Registration Statement by
the Company, the Company shall effect such registrations to permit the sale of
the Registrable Securities covered thereby in accordance with the intended
method or methods of disposition thereof, and in connection with such Piggy-Back
Registration Statement the Company shall:

         (a)  Prior to the filing of the Piggy-Back Registration Statement or
any Prospectus or any amendments or supplements thereto, the Company shall
provide Licensors with a copy of such Piggy-Back Registration Statement or any
Prospectus or any amendments or supplements thereto.

         (b)  Notify the selling Holders of Registrable  Securities promptly
(but in any event within five business days), and confirm such notice in
writing:  (i) when a Prospectus or any Prospectus supplement or post-effective
amendment has been filed, and, with respect to a Piggy-Back Registration
Statement or any

<PAGE>

post-effective amendment, when the same has become effective under the
Securities Act, and (ii) of the issuance by the SEC of any stop order suspending
the effectiveness of a Piggy-Back Registration Statement or of any order
preventing or suspending the use of any preliminary prospectus or the initiation
of any proceedings for that purpose.

         (c)  Use its  reasonable  best  efforts to prevent  the  issuance of
any order suspending the effectiveness of a Piggy-Back Registration Statement or
of any order preventing or suspending the use of a Prospectus or suspending the
qualification (or exemption from qualification) of any of the Registrable
Securities for sale in any jurisdiction and, if any such order is issued, to use
its reasonable best efforts to obtain the withdrawal of any such order at the
earliest practicable time.

         (d)  Furnish to each selling  Holder of  Registrable  Securities  at
the sole expense of the Company one conformed copy of the Piggy-Back
Registration Statement, as applicable, and each post-effective amendment
thereto.

         (e)  Deliver to each selling  Holder of  Registrable  Securities  at
the sole expense of the Company as many copies of the Prospectus or Prospectuses
(including each form of preliminary prospectus) and each amendment or supplement
thereto; and, subject to the last paragraph of this Section 4, the Company
consents to the use of such Prospectus and each amendment or supplement thereto
by each of the selling Holders of Registrable Securities in connection with the
offering and sale of the Registrable Securities covered by such Prospectus and
any amendment or supplement thereto.

         (f)  Prior to any public offering of Registrable Securities,  to use
its reasonable best efforts to register or qualify, and to cooperate with the
selling Holders of Registrable Securities in connection with the registration or
qualification (or exemption from such registration or qualification) of such
Registrable Securities for offer and sale under the securities or blue sky laws
of such jurisdictions within the United States as any selling Holder reasonably
requests; keep each such registration or qualification (or exemption therefrom)
effective during the period such Piggy-Back Registration Statement is required
to be kept effective and do any and all other acts or things reasonably
necessary or advisable to enable the disposition in such jurisdictions of the
Registrable Securities covered by the applicable Piggy-Back Registration
Statement; provided, however, that the Company shall not be required to (i)
qualify to do business in any jurisdiction where it would not otherwise be
required to qualify but for this Section 4(f), (ii) subject itself to general
taxation in any such jurisdiction, (iii) file a general consent to service of
process in any such jurisdiction, (iv) provide any undertakings that cause the
Company material expense or burden, or (v) make any change in its charter or
by-laws, which in each case the Board determines to be contrary to the best
interests of the Company and its stockholders.

         (g)  Cooperate  with the selling  Holders of  Registrable  Securities
to facilitate the timely preparation and delivery of certificates representing
Registrable Securities to be sold, which certificates shall not bear any
restrictive legends and shall be in a form in compliance with any applicable
rules of a stock exchange on which the Common Stock is then listed; and enable

<PAGE>

such Registrable Securities to be in such denominations and registered in such
names as Holders may reasonably request.

         (h) Upon the occurrence of any event or any information  becoming
known to the Company that makes any statement made in such Piggy-Back
Registration Statement or related Prospectus or any document incorporated or
deemed to be incorporated therein by reference untrue in any material respect,
as promptly as practicable prepare and (subject to Section 4(a) hereof) file
with the SEC, at the sole expense of the Company, a supplement or post-effective
amendment to such Piggy-Back Registration Statement or a supplement to the
related Prospectus or any document incorporated or deemed to be incorporated
therein by reference, or file any other required document so that, as thereafter
delivered to Licensors of the Registrable Securities being sold thereunder, any
such Prospectus will not contain an untrue statement of a material fact or omit
to state a material fact required to be stated therein or necessary to make the
statements therein, in light of the circumstances under which they were made,
not misleading.

         (i)  Comply with all  applicable  rules and  regulations  of the SEC
and make generally available to its security holders earnings statements
satisfying the provisions of Section 11(a) of the Securities Act and Rule 158
thereunder (or any similar rule promulgated under the Securities Act) no later
than 90 days after the end of any 12-month period (or 120 days after the end of
any 12-month period if such period is a fiscal year) commencing on the first day
of the first fiscal quarter of the Company after the effective date of a
Piggy-Back Registration Statement, which statements shall cover said 12-month
periods.

         (j)  Cooperate with each seller of Registrable Securities covered by
any Piggy-Back Registration Statement in connection with any filings required to
be made with the National Association of Securities Dealers, Inc. (the "NASD").

         (k)  Use its reasonable best efforts to cause all Registrable
Securities relating  to  any  Piggy-Back  Registration  Statement  to  be
listed on each securities  exchange,  if any, on which similar securities issued
by the Company are then listed.

         The Company may require  each seller of  Registrable  Securities  as to
which any registration is being effected to furnish to the Company such
information regarding such seller and the distribution of such Registrable
Securities as the Company may, from time to time, reasonably request. The
Company may exclude from such registration the Registrable Securities of any
seller so long as such seller fails to furnish such information within a
reasonable time after receiving such request. Each seller as to which any
Piggy-Back Registration Statement is being effected agrees to furnish promptly
to the Company all information required to be disclosed in order to make the
information previously furnished to the Company by such seller not materially
misleading.

         Each Holder of Registrable  Securities  understands that the Securities
Act may require delivery of a Prospectus in connection with any sale thereof
pursuant to a Piggy-Back Registration Statement, and each such Holder shall
comply with the applicable Prospectus delivery requirements of the Securities
Act in connection with any such sale.

<PAGE>

         Each Holder of  Registrable  Securities  agrees by  acquisition of such
Registrable Securities that, upon actual receipt of any notice from the Company
of the happening of any event of the kind described in Section 4(b)(ii) hereof
or any information becoming known that makes any statement made in such
Piggy-Back Registration Statement or related Prospectus or any document
incorporated or deemed to be incorporated therein by reference untrue in any
material respect, such Holder will forthwith discontinue disposition of such
Registrable Securities covered by such Piggy-Back Registration Statement or
Prospectus to be sold by such Holder until such Holder's receipt of the copies
of the supplemented or amended Prospectus contemplated by Section 4(e) hereof,
or until it is advised in writing (the "Advice") by the Company that the use of
the applicable Prospectus may be resumed, and has received copies of any
amendments or supplements thereto.

5.       REGISTRATION EXPENSES

         (a)  All Registration Expenses  shall  be  borne  by  the  Company.
Notwithstanding the foregoing, the sellers of the Registrable Securities being
registered shall pay all (i) brokerage or underwriting fees, discounts and
commissions attributable to the sale of such Registrable Securities, (ii) the
fees and disbursements of any counsel or other advisors or experts retained by
such sellers (severally or jointly), and (iii) transfer taxes on resale of any
of the Registrable Securities by such sellers.

         (b)  For purposes of this Agreement, "Registration Expenses" shall mean
all fees and expenses incident to the compliance with this Agreement by the
Company (other than fees and expenses referred to in the second sentence of
Section 5(a) hereof), including, without limitation, (i) all registration and
filing fees, including, without limitation, (A) any SEC or NASD filing fees and
(B) fees and expenses of compliance with state securities or blue sky laws, (ii)
duplicating and copying expenses, (iii) messenger, telephone and delivery
expenses incurred by the Company, (iv) all fees and disbursements of counsel for
the Company, (v) fees and expenses of all other Persons retained by the Company,
including annual or special audit and "comfort" letters, (vi) stock exchange
listing fees and expenses, if any, and (vii) the expenses relating to printing
and distributing the Piggy-Back Registration Statement and any other documents
necessary in order to comply with this Agreement.

6.       INDEMNIFICATION AND CONTRIBUTION

         (a)  The Company  agrees to indemnify and hold  harmless each Holder of
Registrable Securities, the officers and directors of each such Person, and each
Person, if any, who controls any such Person within the meaning of either
Section 15 of the Securities Act or Section 20 of the Exchange Act (each, a
"Participant"), from and against any and all losses, claims, damages and
liabilities (collectively, "Losses") (including, without limitation, the
reasonable legal fees and other expenses actually incurred in connection with
any suit, action, proceeding (including any governmental or regulatory
investigation), claim or demand (a "Claim")) caused by, arising out of or based
upon any untrue statement or alleged untrue statement of a material fact
contained in any Piggy-Back Registration Statement (or any amendment thereto) or
Prospectus (as amended or supplemented from time to time) or any preliminary

<PAGE>

prospectus, or caused by, arising out of or based upon any omission or alleged
omission to state therein a material fact required to be stated therein or
necessary to make the statements therein, in the case of the Prospectus in light
of the circumstances under which they were made, not misleading, except insofar
as such Losses are caused by any untrue statement or omission or alleged untrue
statement or omission made in reliance upon and in conformity with information
relating to any Participant furnished to the Company in writing by such
Participant expressly for use therein; provided, however, that the Company will
not be liable if such untrue statement or omission or alleged untrue statement
or omission was contained or made in any preliminary prospectus and corrected in
the Prospectus or any amendment or supplement thereto and the Prospectus does
not contain any other untrue statement or omission or alleged untrue statement
or omission of a material fact that was the subject matter of the related
proceeding and any such Loss suffered or incurred by the Participants resulted
from any Claim by any Person who purchased Registrable Securities which are the
subject thereof from such Participant and it is established in the related
proceeding that such Participant failed to deliver or provide a copy of the
Prospectus (as amended or supplemented) to such Person with or prior to the
confirmation of the sale of such Registrable Securities sold to such Person if
required by applicable law, unless such failure to deliver or provide a copy of
the Prospectus (as amended or supplemented) was a result of noncompliance by the
Company with this Agreement.

         (b)  Each Participant agrees,  severally and not jointly,  to indemnify
and hold harmless the Company, its directors, its officers who sign the
Piggy-Back Registration Statement, and each Person who controls the Company
within the meaning of Section 15 of the Securities Act or Section 20 of the
Exchange Act to the same extent as the foregoing indemnity from the Company to
each Participant, but only with reference to information relating to such
Participant furnished to the Company in writing by such Participant expressly
for use in such Piggy-Back Registration Statement or Prospectus, any amendment
or supplement thereto, or any preliminary prospectus. The liability of any
Participant under this paragraph shall in no event exceed the proceeds received
by such Participant from sales of Registrable Securities giving rise to such
obligations.

         (c)  If any Claim  shall be brought or  asserted  against any Person in
respect of which indemnity may be sought pursuant to either of the two preceding
paragraphs, such Person (the "Indemnified Person") shall promptly notify the
Person against whom such indemnity may be sought (the "Indemnifying Person") in
writing, and the Indemnifying Person shall retain counsel reasonably
satisfactory to the Indemnified Person to represent the Indemnified Person and
any others the Indemnifying Person may reasonably designate in such Claim and
shall pay the reasonable fees and expenses actually incurred by such counsel
related to such proceeding; provided, however, that the failure to so notify the
Indemnifying Person shall not relieve it of any obligation or liability which it
may have hereunder or otherwise. In any such proceeding, any Indemnified Person
shall have the right to retain its own counsel, but the fees and expenses of
such counsel shall be at the expense of such Indemnified Person unless (i) the
Indemnifying Person and the Indemnified Person shall have mutually agreed to the
contrary, (ii) the Indemnifying Person shall have failed within a reasonable
period of time to retain counsel reasonably satisfactory to the Indemnified
Person, or (iii) the named parties in any such proceeding (including any
impleaded parties) include both the Indemnifying Person and the Indemnified

<PAGE>

Person or any affiliate and representation of both parties by the same counsel
would be inappropriate due to actual or potential differing interests between
them. The Indemnifying Person shall not, in connection with any one such
proceeding or separate but substantially similar related proceedings in the same
jurisdiction arising out of the same general allegations, be liable for the fees
and expenses of more than one separate firm (in addition to any local counsel)
for all Indemnified Persons, and all such fees and expenses shall be reimbursed
promptly as they are incurred. If the Company shall be the Indemnifying Person,
any such separate firm for the Indemnified Persons shall be designated in
writing by Participants who sold a majority in interest of Registrable
Securities sold by all such Participants and reasonably acceptable to the
Company. If the Company shall be the Indemnified Person, any such separate firm
for the Company, its directors, its officers who sign a Piggy-Back Registration
Statement and such control Persons of the Company shall be designated in writing
by the Company. No Indemnifying Person shall be liable for any settlement of any
proceeding effected without its prior written consent (which consent shall not
be unreasonably withheld or delayed), but if settled with such consent or if
there be a final judgment for the plaintiff for which the Indemnified Person is
entitled to indemnification pursuant to this Agreement, the Indemnifying Person
shall indemnify and hold harmless each Indemnified Person from and against any
loss or liability by reason of such settlement or judgment. No Indemnifying
Person shall, without the prior written consent of the Indemnified Persons
(which consent shall not be unreasonably withheld or delayed), effect any
settlement or compromise of any pending or threatened proceeding in respect of
which any Indemnified Person is or could have been a party, or indemnity could
have been sought hereunder by such Indemnified Person, unless such settlement
involves only the payment of money damages that are actually paid by the
Indemnifying Person or includes an unconditional written release of such
Indemnified Person, in form and substance reasonably satisfactory to such
Indemnified Person, from all liability on claims that are the subject matter of
such proceeding.

         (d)  If  the  indemnification  provided  for in  the  first and  second
paragraphs of this Section 6 is for any reason unavailable to, or insufficient
to hold harmless, an Indemnified Person in respect of any Losses, then each
Indemnifying Person under such paragraphs, in lieu of indemnifying such
Indemnified Person thereunder and in order to provide for just and equitable
contribution, shall contribute to the amount paid or payable by such Indemnified
Person as a result of such Losses, in such proportion as is appropriate to
reflect the relative fault of the Indemnifying Person or Persons on the one hand
and the Indemnified Person or Persons on the other in connection with the
statements or omissions or alleged statements or omissions that resulted in such
Losses (or actions in respect thereof) as well as any other relevant equitable
considerations. The relative fault of the parties shall be determined by
reference to, among other things, whether the untrue or alleged untrue statement
of a material fact or the omission or alleged omission to state a material fact
relates to information supplied by the Indemnifying Person on the one hand or
such Indemnified Person, as the case may be, on the other, the parties' relative
intent, knowledge, access to information and opportunity to correct or prevent
such statement or omission, and any other equitable considerations appropriate
in the circumstances.

         (e)  The  parties  agree  that it  would  not be just and equitable  if
contribution pursuant to this Section 6 were determined by pro rata allocation
or by any other method of allocation that does not take account of the equitable
considerations referred to in the immediately preceding paragraph. The amount

<PAGE>

paid or payable by an Indemnified Person as a result of the Losses referred to
in the immediately preceding paragraph shall be deemed to include, subject to
the limitations set forth above, any reasonable legal or other expenses actually
incurred by such Indemnified Person in connection with investigating or
defending any such Claim. Notwithstanding the provisions of this Section 6, in
no event shall a Participant be required to contribute any amount in excess of
the amount by which proceeds received by such Participant from sales of
Registrable Securities exceeds the amount of any damages that such Participant
has otherwise been required to pay or has paid by reason of such untrue or
alleged untrue statement or omission or alleged omission. No Person guilty of
fraudulent misrepresentation (within the meaning of Section 11(f) of the
Securities Act) shall be entitled to contribution from any Person who was not
guilty of such fraudulent misrepresentation.

         (f)  Any  Losses  for  which  an  indemnified   party  is  entitled  to
indemnification or contribution under this Section shall be paid by the
Indemnifying Person to the Indemnified Person as such Losses are incurred. The
indemnity and contribution agreements contained in this Section 6 and the
representations and warranties of the Company set forth in this Agreement shall
remain operative and in full force and effect regardless of (i) any
investigation made by or on behalf of any of Licensors, any Holder, any person
who controls Licensors or any Holder, or any officers or directors of Licensors
or such Holder, and (ii) any termination of this Agreement.

         (g)  The indemnity and contribution covenants contained in this Section
6 are in addition to any liability which any Indemnifying Person may otherwise
have to any Indemnified Person.

7.       RULE 144

         The Company will file the reports  required to be filed by it under the
Exchange Act in a timely manner in accordance with the requirements of the
Exchange Act. The Company will also take such further action as any Holder of
Registrable Securities issued by the Company may reasonably request, to the
extent required from time to time to enable such holder to sell Registrable
Securities without registration under the Securities Act within the limitation
of the exemptions provided by Rule 144(k).

8.       MISCELLANEOUS

         (a)  The  provisions of this Agreement may not be amended,  modified or
supplemented, and waivers or consents to departures from the provisions hereof
may not be given, otherwise than with the prior written consent of (i) the
Company, and (ii) the Holders of not less than a majority in aggregate amount of
the then-outstanding Registrable Securities; provided, however, that Section 4
and this Section 8(a) may not be amended, modified or supplemented without the
prior written consent of each Holder (including any person who was a Holder of
Registrable Securities disposed of pursuant to any Piggy-Back Registration
Statement) affected by any such amendment, modification or supplement.
Notwithstanding the foregoing, a waiver or consent to depart from the provisions
hereof with respect to a matter that relates exclusively to the rights of
Holders of Registrable Securities whose securities are being sold pursuant to a

<PAGE>

Piggy-Back Registration Statement and that does not directly or indirectly
affect, impair, limit or compromise the rights of other Holders of Registrable
Securities may be given by Holders of at least a majority in aggregate amount of
the Registrable Securities being sold by such Holders pursuant to such
Piggy-Back Registration Statement.

         (b)  Any notice  herein  required or  permitted to be given shall be in
writing and may be personally served or delivered by nationally-recognized
overnight courier or by facsimile-machine confirmed telecopy, and shall be
deemed delivered at the time and date of receipt (which shall include telephone
line facsimile transmission). Each party shall provide notice to the other party
of any change in address. The addresses for such communications shall be:

                           If to the Company:

                           LaserSight Incorporated
                           3300 University Boulevard, Suite 140
                           Winter Park, Florida  32792
                           Telecopy: (407) 678-9981
                           Attention: Chief Financial Officer

                           with a copy to:

                           The Lowenbaum Partnership, L.L.C.
                           222 South Central Avenue, Suite 901
                           St. Louis, Missouri 63105
                           Telecopy: (314) 746-4848
                           Attention: Timothy L. Elliott

                           and

                           Sonnenschein Nath & Rosenthal
                           8000 Sears Tower
                           Chicago, Illinois 60606
                           Telecopy: (312) 876-7934
                           Attention: Paul Miller

                           If to Licensors:

                           Luis A. Ruiz, M.D. and Sergio Lenchig
                           Calle 120 No. 20A-44, Apartment 401
                           Santefe de Bogota, Colombia
                           South America
                           Telecopy:57-1-213-8462 - attn: Sergio Lenchig
                           Telecopy:57-1-218-5730 - attn: Luis A. Ruiz, M.D.
<PAGE>

                           and

                           Mezullo & McCandlish
                           1111 East Main Street, 15th Floor
                           Richmond, Virginia 23219
                           Telecopy: (804) 775-3800
                           Attention: Allan S. Buffenstein, Esq.

         (c)  This  Agreement shall inure to the benefit of and be binding  upon
the successors and assigns of each of the parties hereto, and the Holders;
provided, however, that this Agreement shall not inure to the benefit of, or be
binding upon, a successor or assign of a Holder unless and to the extent such
successor or assign holds Registrable Securities.

         (d)  This  Agreement  may be  executed  in two  or  more  counterparts,
including, without limitation, by facsimile transmission, all of which
counterparts shall be considered one and the same agreement and shall become
effective when counterparts have been signed by each party and delivered to the
other party. In the event any signature page is delivered by facsimile
transmission, the party using such means of delivery shall cause additional
original executed signature pages to be delivered to the other parties.

         (e) The headings in this Agreement are for convenience of reference and
shall not form a part of, or affect the interpretation of, this Agreement.

         (f)  This  Agreement shall be governed by and  construed in  accordance
with the laws of the State of Delaware applicable to contracts made and to be
performed in that state. The parties hereto irrevocably consent to the
jurisdiction of the United States federal courts and state courts located in the
County of New Castle in the State of Delaware, in any suit or proceeding based
on or arising under this Agreement and irrevocably agree that all claims in
respect of such suit or proceeding may be determined in such courts. The parties
hereto irrevocably waive the defense of an inconvenient forum to the maintenance
of such suit or proceeding. The parties hereto further agree that service of
process upon the parties hereto mailed by first class mail shall be deemed in
every respect effective service of process upon each such party in any such suit
or proceeding. Nothing herein shall affect either party's right to serve process
in any other manner permitted by law. The parties hereto agree that a final
non-appealable judgment in any such suit or proceeding shall be conclusive and
may be enforced in other jurisdictions by suit on such judgment or in any other
lawful manner.

         (g)  Whenever  the  consent  or  approval  of  Holders  of a  specified
percentage of Registrable Securities is required hereunder, Registrable
Securities held by the Company or its affiliates (as such term is defined in
Rule 405 under the Securities Act) shall not be counted in determining whether
such consent or approval was given by the Holders of such required percentage.

<PAGE>

         (h)  Holders  of  Registrable   Securities  are  intended  third  party
beneficiaries of the agreements made hereunder between the Company and Licensors
and shall have the right to enforce this Agreement to the extent they deem such
enforcement necessary or advisable to protect their rights hereunder.

         (i)  This  Agreement,   together  with  the  Amendment  and  the  other
agreements among the parties of even date herewith or therewith, is intended by
the parties as a final expression of their agreement and intended to be a
complete and exclusive statement of the agreement and understanding of the
parties hereto in respect of the subject matter contained herein. There are no
restrictions, promises, warranties or undertakings, other than those set forth
or referred to herein with respect to the registration rights granted by the
Company with respect to the Registrable Securities. This Agreement supersedes
all prior agreements and understandings among the parties with respect to such
subject matter.

         (j)  The Company  agrees that during the time period  beginning  on the
dated hereof and continuing until the Company has satisfied its obligations
hereunder or until such obligations have expired, the Company will not enter
into any agreement related to the registration of its securities which is
inconsistent with the rights granted to the Holders pursuant to this Agreement.
The rights granted to Licensors pursuant to this Agreement do not conflict with
any other agreements to which the Company is a party.

         IN WITNESS  WHEREOF,  the parties have caused this Agreement to be duly
executed as of the date first above written.

LASERSIGHT INCORPORATED                     LICENSORS

By:  /s/Michael R. Farris                    /s/Luis A. Ruiz, M.D.
    -------------------------               -------------------------
    Michael R. Farris                       Luis A. Ruiz, M.D.
    President and CEO
                                             /s/Sergio Lenchig
                                            -------------------------
                                            Sergio Lenchig

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