Document:

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                                                                   Exhibit 10.22

                              EMPLOYMENT CONTRACT

Agreement has this day been made between Amersham Pharmacia Biotech AB
hereinafter called "the Company" and Mr. Par-Erik Sandlund hereinafter called
"the Employee".

SECTION 1 EMPLOYMENT AND EMPLOYEE'S OBLIGATIONS

          The Company appoints the Employee Chief Financial Officer of Amersham
          Pharmacia Biotech, entrusted with all powers of daily management, as
          delegated by the Chief Executive Officer.

          In this capacity the Employee shall perform his duties as specified by
          the Chief Executive Officer.

          The Employee shall devote the whole of his working time to his duties
          under this agreement and may not undertake any other duties without a
          written consent from the Company.

          The Employee is based in Uppsala, Sweden. A relocation of headquarters
          to another location is subject to a new agreement.

SECTION 2 FIRST DAY OF EMPLOYMENT

          This agreement shall run from the 5th of August 1997. The employment
          shall be considered to be for an indefinite period. The Employee's
          employment with the Company shall be considered continuous as from 1
          August 1991.

SECTION 3 REMUNERATION

3.1       Base Salary

          The Employee's annual base salary shall as from 1 October 1997 be SEK
          1,017,750 payable in arrears in twelve instalments per annum. With
          effect from 1 January 1998, the annual base salary shall be SEK
          1,053,371 and with effect from 1 January 1999 the annual base salary
          shall be SEK 1,250,000.

          The salary will be reviewed annually, any change will be effective
          January 1. Next review will be made in 2000.
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          Any bonuses, gifts or other payments which the Company may grant or
          make to the Employee from time to time, to the extent that they are
          not required by law or by this agreement, shall be treated as having
          been granted or made at the Company's absolute discretion and shall
          not be considered a part of the Employee's contractual remuneration.

3.2       Short Term Incentives

          The Employee will be entitled to a payment based upon individual
          performance and performance of Amersham Pharmacia Biotech, provided
          predetermined objectives are met. The maximum amount is 40 per cent of
          the basic salary and associated conditions will be in line with Group
          policy.

          Details regarding objectives and incentives will be settled in a
          separate agreement.

3.3       Long Term Incentives

          The Employee will be eligible for an allocation of Nycomed Amersham
          shares, provided certain predetermined objectives related to the
          performance of Amersham Pharmacia Biotech are met. The Company will
          pay employer's contribution on any allocation.

          Objectives are set and evaluation of performance will be made at the
          absolute discretion of the Company. Other associated conditions are
          described in a separate document.

          Shares will be purchased by the Company and held in a trust.

3.4       Share Option Scheme

          The Employee will be eligible for inclusion in the share option scheme
          of Nycomed Amersham. Income tax levied on any gain will be borne by
          the Employee and Employer's contribution by the Company.

          All conditions related to the Share Option Scheme are set and
          decisions made at the Company's absolute discretion. Any change of
          conditions shall not constitute breach of this agreement.

3.5       International Relocation Allowance

          In the event of relocation of the headquarters of Amersham Pharmacia
          Biotech within a three year period following the start of the Company,
          a lump sum will be paid to the Employee, provided the Employee is
          willing to relocate and is offered a similar position. In case the
          Employee declines to relocate, no allowance will be paid.

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          In case Amersham Pharmacia Biotech decides not to relocate, the lump
          sum will be paid to the Employee. Income tax levied on the payment
          will be borne by the Employee and employer's contribution by the
          Company.

          The annual report set aside for a future lump sum payment is GBP
          37,923. With effect from 1 January 1999 the amount is 27,844. The
          amount is based on a possible relocation to the United Kingdom. The
          amount will reviewed annually and any decision to revise it will be
          at the discretion of the Company.

          Should Amersham Pharmacia Biotech decide to relocate to another
          location and country than the United Kingdom, the same arrangement
          and similar conditions shall apply.

3.6       Company Car

          The Employee is entitled to a Company car for business and private
          use. Standard of car shall be in line with a Volvo S70. The Company
          shall meet all expenses, except fuel for private mileage. Other
          conditions related to the car will be in line with the Company car
          policy as amended from time to time.

          The Employee can alternatively elect to receive a car allowance in
          cash, paid out per month.

SECTION 4 EXPENSES

          The Company will reimburse the Employee for all reasonable business
          expenses incurred by him in the course of the employment. The Employee
          must provide receipts and other evidence of such business expenses.

SECTION 5 PENSION AND INSURANCE COVERAGE

          The Company will annually contribute towards a pension scheme selected
          and designed by the Employee, "Ordinary Retirement Scheme". Company
          contribution shall be equal to 20 per cent of base pay and average
          bonus over a three-year period, but in no case above the maximum
          contribution deductible according to the tax rules. Earnings in
          excess of 50 base amounts will not be taken into account (base
          amount: SEK 36,400, 50 base amounts currently 1,820,000). Disability
          coverage and survivor's benefits shall be a part of the arrangement
          and be on a satisfactory level.

          Retirement age is 60. The Company will in addition to the Ordinary
          Retirement Scheme arrange for early retirement benefits covering the
          period 60 to 65 years of age (enclosure). Subject to separate
          agreement between Company and the Employee, early retirement may be
          postponed and start at any other age between 60 and 65.
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          Funding of early retirement benefits will be decided at the discretion
          of the Company.

          Social charges on levied on contributions to pension arrangements will
          be paid by the Company.

SECTION 6 HOLIDAY ENTITLEMENT

          The Employee is entitled to 30 days of holiday. Entitlement shall
          accrue month by month on a pro rata basis.

SECTION 7 SOCIAL SECURITY CONTRIBUTIONS AND INCOME TAXES

          The Employee will pay tax and social security contributions in
          accordance with Swedish regulations and the Company will withhold the
          necessary deductions for this.

          The Company pays Employer's Contribution according to local rules.

SECTION 8 TERMINATION OF AGREEMENT

          The agreement may be terminated by either party giving to the other
          six months advance notice in writing. The Company reserves the right
          to remove the Employee from his position during the time of notice or
          part of it. During the time of notice the Employee is entitled to the
          conditions of this agreement.

          Should the agreement be terminated by the Company for other reason
          than material breach of agreement, the Employee shall receive in
          addition to time of notice a severance pay amounting to twelve months
          salary as per date the day before giving notice. The severance pay
          shall, unless otherwise agreed upon, be paid every month starting the
          first month after the effective date of employment. Full vesting to
          date of early retirement benefits accrued to date shall apply.

          Should the agreement be terminated by the Employee, entitlement to
          early retirement benefits shall be forfeited.

          The Company reserves the right to terminate this agreement at any time
          without advance notice or severance pay in the event of material
          breach of contract, including act of gross negligence or gross
          misconduct by the Employee and wilful failure to perform his duties
          with the Company.

          Material breach of contract after the termination of employment may
          result in the immediate cessation of severance pay and other benefits.

          This clause together with other clauses will be reviewed in connection
          with a relocation of headquarters to another location. Relocation is
          subject to a new agreement.

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SECTION 9 CONFIDENTIALLY

          The Employee shall not at any time other than the course of his duties
          without the previous consent in writing of the Company divulge or make
          known to anyone any secrets or any technical, commercial, financial or
          other information of a confidential nature unless such information is
          already in the public domain relating to the business or customers of
          the Group so as to the extent that all such information has become a
          matter of public record. All papers and documents used by the Employee
          in the course of his employment are and will remain the property of
          the Company and will be delivered up to the Company on the termination
          of the Employee's agreement with the Company or any of its
          subsidiaries. This clause operates independently of the existence of
          this Agreement.

SECTION 10 PATENT, SECRET PROCESSES AND IMPROVEMENTS

          Any discovery or invention or  secret process or improvement in
          procedure made or discovered by the Employee while in the service of
          the Company whether before or after the date of this Agreement in any
          way affecting or relating to the business of the Company or of any
          subsidiary company or capable of being used or adapted for use therein
          or in connection therewith shall forthwith be disclosed to the Company
          and should belong to and be the absolute property of the Company.

SECTION 11 RESTRICTIVE COVENANT

          The Employee hereby agrees during his employment and twelve months
          after the effective date of termination of employment not to directly
          or indirectly

          (i) solicit or approach any person for the purpose of offering to
          supply or procure the supply of goods of services similar to those
          then sold or supplied by Amersham Pharmacia Biotech where that person
          was one to whom the Employee knows Amersham Pharmacia Biotech sold or
          supplied goods or services.

          (ii) incite or procure the breach or amendment of any contract for the
          supply of goods or services, agreement or pattern of dealing to which
          Amersham Pharmacia Biotech is party or by which Amersham Pharmacia
          Biotech benefits.

          (iii) entice or solicit, or endeavour to entice or solicit any
          employee of Amersham Pharmacia Biotech to leave such employment.

          (iv) entice of solicit, or endeavour to entice or solicit any contract
          worker or independent contractor to terminate or not renew his/her
          contract for services with Amersham Pharmacia Biotech.

          (v) neither personally or by an agent directly or indirectly either on
          the Employee's own account or for any other person, firm or company
          carry on or be engaged or interested in any business which competes
          with any business carried out at the date of termination of employment
          by Amersham Pharmacia Biotech.

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SECTION 12 OTHER EMPLOYMENT CONDITIONS

          As regards employment conditions that are not regulated in this
          contract the policies of Amersham Pharmacia Biotech AB shall apply.

SECTION 13 OTHER CLAUSE

          This agreement supersedes all earlier written or oral agreements
          between the Employee and Amersham Pharmacia Biotech.

          The agreement constitutes the entire agreement between the parties and
          it may only be changed by a written agreement between the parties,
          except for areas explicitly mentioned in this agreement.

SECTION 14 JURISDICTION

          This contract is construed according to and governed by Swedish law.
          Any dispute about the agreement shall be submitted to a Swedish
          Arbitration court if the parties cannot come to a consensus as to the
          interpretation of the conditions. Cost for the arbitration proceedings
          shall be defrayed by the Company provided the Employee has not unduly
          instigated the arbitration procedure. In such case, the arbitrators
          shall determine the distribution of arbitration cost.

SECTION 15 COUNTERPARTS

          The agreement has been drawn up in duplicate of which the parties have
          taken one copy each.

Signed /s/ Arne Forsell                      /s/ Per Erik Sandlund
       ---------------------------------     ----------------------------------
       Arne Forsell                          Per Erik Sandlund
       Acting CEO
       Amersham Pharmacia Biotech

       18 February 1999                      18 February 1999
       ----------------                      ----------------
       date                                  date

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                                                                       enclosure

EARLY RETIREMENT BENEFITS

1.  BENEFITS

Enhanced Company benefits are:

     --   early retirement pensions (retirement benefits prior to the normal
          retirement age of 65), and

     --   survivors' pensions

Early retirement pension amounts to 70 per cent of pensionable earnings up to a
maximum of earnings equivalent to 50 base amounts ("basbelopp", currently
SEK 36,400) will be paid from the age 60 until the age of 65. Any Disability
pension received from Social Security or Ordinary Retirement Scheme shall
reduce the Early Retirement Pension to such an extent that the total resulting
pension does not exceed 70 per cent of pensionable earnings up to 50 base
amounts.

The contributions that would have been made to the Employee's Ordinary
Retirement Arrangement had the Employee stayed in service until 65, will be
made by the Company.

Survivors' pension amount relating to early retirement benefits in the entire
accrued entitlement at the time of death, should the Employee die prior to
payment commencing. Payment will be made over a five-year period. If the
Employee dies between 60 and 65, during the period under which the early
retirement pension is being paid, the Company will continue payment under the
same terms.

Any Survivor's pension received from Social Security and/or Ordinary Retirement
Scheme shall reduce the Early Retirement Pension to such an extent that the
total resulting pension does not exceed 70 per cent of pensionable earnings up
to 50 base amounts.

2.  VESTING AND ACCRUAL

Benefits are deemed to accrue uniformly over the period up to the retirement
age. Vesting Service is service in the current position.

Consequences for early retirement benefits of termination of employment are
set out in the employment agreement.

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                                                            enclosure

3. INCREASE OF BENEFITS

The Company shall make an annual review of benefits in payment and accrued
benefits for the Employee and will normally increase these in line with the
increase in ITP pensions. In the event of changes to ITP arrangements
invalidating this approach, the Company shall identify a suitable alternative
comparator. Decisions on benefit increases are made at the discretion of the
Company.

Review for possible increases of accrued benefits also applies after
termination of employment, provided benefits are vested.

4. FUNDING

Decision on funding, including change of funding will be made at the discretion
of the Company.

                                                                               8<PAGE>   1
                                                                   Exhibit 10.23

          Amersham Pharmacia Biotech Europe GmbH Tel +49 (0) 761/4519
                                Munzinger Qtr. 9 Fax +49 (0) 761/4510
                               D-79111 Frelburg

Agreement has this day been made between Pharmacia Biotech Europe GmbH,
hereinafter called "the Company" and Mr Lars Erik Utterman (430815), hereinafter
called "the Employee".

SECTION 1 EMPLOYMENT AND EMPLOYEE'S OBLIGATIONS

          The Company hires the Employee for the position as President,
          entrusted with all powers of daily management, as delegated by the
          Board of Directors.

          As President the Employee shall perform his duties as specified yearly
          by the Board of Directors and ensure that the Company is being managed
          in accordance with the law and decrees of Germany and the different
          countries in which the company operates in Europe.

          The Employee shall devote the whole of his working time to his duties
          under this agreement and may not undertake any other duties without a
          written consent from the Chairman of the Board.

          Upon termination of this contract or upon earlier request, the
          Employee shall return all documents, correspondence, reports, material
          and equipment which were available to him during the course of
          employment.

SECTION 2 FIRST DAY OF EMPLOYMENT AND CONTRACT PERIOD

          This agreement shall run from the 1st of July 1994. The employment
          shall be considered to be for an undefinite period.

          If the Employee is made redundant due to restructuring, the Company
          will use its best endeavours to provide the Employee with a position
          within the Pharmacia group commensurate to his level of experience and
          previous status.
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[PHARMACIA BIOTECH LOGO]

SECTION 3 REMUNERATION

3.1       Base Salary

          The Employee's annual base salary shall be DEM 475.000 payable
          according to local practise. The salary will be reviewed yearly,
          starting on January 1, 1995.

          Any bonuses, gifts or other payments which the Company may grant or
          make to the Employee from time to time, to the extent that they are
          not required by law, by a collective bargaining agreement or by this
          contract, shall be treated as having been granted or made at the
          Company's absolute discretion and shall not be considered a part of
          the Employee's contractual remuneration.

3.3       Bonus Payments

          The Employee will be entitled to a payment based upon individual and
          local company performance. The maximum bonus amount is 25 per cent of
          the basic annual salary and is calculated in accordance with the
          achievement of predetermined objectives. Details regarding objectives
          and incentives will be settled in a separate agreement.

SECTION 4 HOLIDAY ENTITLEMENT

          The Employee shall be entitled to 30 days of holiday in any calendar
          year which will accrue pro-rated month by month from the date of
          commencement. In addition to holiday entitlement, the Employee shall
          be entitled to all statutory, national and public holidays and will be
          paid in accordance with local regulations relating to holiday pay.

SECTION 5 COMPANY CAR

          The Employee is entitled to a Company car in accordance with his
          position as Geschaftsfuhrer and the local Company car scheme as
          published and amended by the Company.

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[PHARMACIA BIOTECH LOGO]

SECTION 6 EXPENSES

          The Company will reimburse the Employee for all reasonable business
          expenses incurred by him during the course of the employment. The
          Employee must provide receipts and other evidence of such business
          expenses.

SECTION 7 PENSION

          The Company shall yearly pay NLG 42,000 premiums to a pension
          insurance owned by the Employee. The Company's contribution will be
          reviewed in conjunction with the salary review.

SECTION 8 MEDICAL COVER AND INCAPACITY FOR WORK

          In the event of the Employee being prevented from discharging his
          duties, the Company will pay his full salary up to three months.
          Long-term disability is covered through a separate insurance.

SECTION 9 HOME LEAVE

          The Employee and his accompanying family shall be entitled to be
          reimbursed for one trip home for each year of service. The air fare of
          economy class or air travel will be paid the first five years of
          service.

SECTION 10 LANGUAGE TRAINING

          As part of the preparation for this employment the Company agrees to
          pay the cost of basic language courses for the Employee and his spouse
          up to a negotiated amount.
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[PHARMACIA BIOTECH LOGO]

Section 11  TELEPHONE COST AND DAILY NEWSPAPER

          Costs for business calls and subscription fee for a daily newspaper to
          the Employee's home are paid by the Company.

Section 12  SOCIAL SECURITY INCOME AND LOCAL TAXES

          The Employee will pay tax and social security contributions in
          accordance with local regulations in each country and the Company will
          withhold the necessary deductions herefor.

Section 13  TERMINATION OF CONTRACT

          This contract may be terminated by either party giving to the other
          six months' notice in writing. The Company reserves the right to
          remove the Employee from his position during the time of notice or
          part of it. During the time of notice the Employee is entitled to the
          conditions of this agreement with the exception of bonus.

          Should the contract be terminated by the Employer, the Employee shall
          receive in addition to time of notice a severance pay amounting to
          twelve months' salary as per date the day before giving the notice.
          The severance pay shall, unless otherwise agreed upon, be paid every
          month starting the first month after the expiry of the contract
          period. An additional six months severance pay will be paid when the
          Employee has reached the age of 55 years.

          The Company will furthermore pay expenses to cover removal
          transportation and insurance of personal belongings to country of
          choice within Europe.

          Any statutory severance pay/indemnities which may be granted the
          Employee shall be deducted from the severance pay stated in this
          contract.

          The Company reserves the right to terminate this contract at any time,
          without prior notice, in the event of misconduct by the Employee,
          including subordination, use of physical violence, unjustified absence
          or tardiness, refusal to carry out duties properly assigned to him,
          disclosure or confidential information relating to the Company or
          giving false or misleading information to the Company either before or
          after the date of this agreement.

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[PHARMACIA BIOTECH LOGO]

SECTION 14 CONFIDENTIALITY

          The Employee shall not at any time other than in the course of his
          duties without the previous consent in writing of the Company divulge
          or make known to anyone any secrets or any technical, commercial,
          financial or other information of a confidential nature unless such
          information is already in the public domain relating to the business
          or customers of the Group so as to the extent that all such
          information has become a matter of public record. All papers and
          documents used by the Employee in the course of his employment are and
          will remain the property of the Company and will be delivered up to
          the Company on the termination of the Employee's agreement with the
          Company or any of its subsidiaries. This clause operates independently
          of the existence of this Agreement.

SECTION 15 PATENT, SECRET PROCESSES AND IMPROVEMENTS

          Any discovery or Inventory secret process or improvement in procedure
          made or discovered by the Employee while in the service of the Company
          whether before or after the date of this Agreement in any way
          affecting or relating to the business of the Company or of any
          subsidiary company or capable of being used or adapted for use therein
          or in connection therewith shall forthwith be disclosed to the Company
          and should belong to and be the absolute property of the Company.

SECTION 16 RESTRICTIVE COVENANT

          The Employee hereby agrees during his employment not to solicit
          business from any person, firm or company who at any time has been a
          customer of the company or done business with or attempt to persuade
          away from the Company any person who has been employed by the Company.

SECTION 17 OTHER EMPLOYMENT CONDITION

          As to the rest the general employment conditions of Pharmacia Biotech
          Europe GmbH will apply.
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[PHARMACIA BIOTECH LOGO]

SECTION 18 JURISDICTION

          Any dispute about the agreement shall be submitted to a Swedish
          Arbitration Court if the parties cannot come to a consensus as to the
          interpretation of the conditions. The costs of the arbitration
          proceedings shall be defrayed by the Company provided that the
          Employee has not unduly instigated the arbitration procedure. In such
          case, the arbitrators will determine the distribution of arbitration
          costs.

SECTION 19 OTHER CLAUSE

          This contract supersedes all earlier written or oral agreements
          between the Employee and different entities within Pharmacia Biotech.

SECTION 20 COUNTERPARTS

          The agreement has been drawn up in duplicate, of which the parties
          have taken one copy each.

Uppsaala,

     Signed   /s/ Arne Forsell              Signed  /s/ Lars Eric Utterman
              -------------------------             ----------------------------
              Arne Forsell                          Lars Eric Utterman
              Chairman of the Board

     Date:    April 12, 1994                Date:   April 12, 1994
              -------------------------             ----------------------------

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