Document:

Exhibit
10.3

 

THE MEDICINES COMPANY

 

Nonstatutory Stock
Option Agreement

Under 1998  Stock Incentive Plan

 

1.                                       Grant
of Option.

 

(a)                                  This
agreement evidences the grant by The Medicines Company, a Delaware corporation
(the “Company”),
on             ,
2004  (the
“Grant Date”) to  [                         ],
an [employee], [consultant], [director] of the Company (the “Participant”), of
an option to purchase, in whole or in part, on the terms provided herein and in
the Company’s 1998 Stock Incentive Plan (the “Plan”),  a total of
[             ]
shares (the “Shares”) of common stock, $0.001 par value per share (“Common
Stock”), of the Company at a price of $[             ]
per Share.  Unless earlier terminated,
this option shall expire on the tenth anniversary of the Grant Date (the “Final
Exercise Date”).  

 

(b)                                 It
is intended that the option evidenced by this agreement shall not be an
incentive stock option as defined in Section 422 of the Internal Revenue
Code of 1986, as amended and any regulations promulgated thereunder (the
“Code”).  Except as otherwise indicated
by the context, the term “Participant”, as used in this option, shall be deemed
to include any person who acquires the right to exercise this option validly under
its terms.

 

2.                                       Vesting
Schedule.

 

(a)                                  This
option will become exercisable (“vest”) in equal monthly installments in
arrears over the four-year period commencing on the Grant Date.  This option shall expire upon, and will not
be exercisable after, the Final Exercise Date.

 

(b)                                 The
right of exercise shall be cumulative so that to the extent the option is not
exercised in any period to the maximum extent permissible it shall continue to
be exercisable, in whole or in part, with respect to all Shares for which it is
vested until the earlier of the Final Exercise Date or the termination of this
option under Section 3 hereof or the Plan. 

 

(c)                                  Notwithstanding anything in this option
to the contrary, in the event that the Participant’s relationship with the
Company is terminated by reason of death or disability (within the meaning of
Section 22(e)(3) of the Code), then, 
in addition to the Shares as to which this option is exercisable as of
such termination date pursuant to the terms hereof, this option shall also
become exercisable for an additional number of Shares equal to 50% of the
Shares covered by this option which were not otherwise

 

 

exercisable as of such
termination date.  For example, if as of
the termination date, 6,000 shares of a 10,000 share stock option had vested
and no shares covered by such option had been exercised, upon such termination
date, the option would become exercisable for an additional 2,000 shares (50%
of (10,000 - 6,000)) or total of 8,000 shares. 

 

3.                                       Exercise
of Option.

 

(a)                                  Form
of Exercise.  Each election to exercise
this option shall be in writing, signed by the Participant, and received by the
Company at its principal office, accompanied by this agreement, and payment in
full in the manner provided in the Plan. 
The Participant may purchase less than the number of Shares covered
hereby, provided that no partial exercise of this option may be for any
fractional share or for fewer than ten whole shares.

 

(b)                                 Continuous
Relationship with the Company Required. 
Except as otherwise provided in this Section 3, this option may not
be exercised unless the Participant, at the time he or she exercises this
option, is, and has been at all times since the date of grant of this option,
an employee, officer or director of, or consultant or advisor to, the Company
or any parent or subsidiary of the Company as defined in Section 424(e) or
(f) of the Code (an “Eligible Participant”).

 

(c)                                  Termination
of Relationship with the Company. 
If the Participant ceases to be an Eligible Participant for any reason,
then, except as provided in paragraphs (d) and (e) below, the right to exercise
this option shall terminate three months after such cessation (but in no event
after the Final Exercise Date), provided  that this option shall
be exercisable only to the extent that the Participant was entitled to exercise
this option on the date of such cessation. 
Notwithstanding the foregoing, if the Participant, prior to the Final
Exercise Date, violates the non-competition or confidentiality provisions of
any employment contract, confidentiality and nondisclosure agreement or other
agreement between the Participant and the Company, the right to exercise this
option shall terminate immediately upon written notice to the Participant from
the Company describing such violation.

 

(d)                                 Exercise
Period Upon Death or Disability.  If
the Participant dies or becomes disabled (within the meaning of
Section 22(e)(3) of the Code) prior to the Final Exercise Date while he or
she is an Eligible Participant and the Company has not terminated such
relationship for “cause” as specified in paragraph (e) below, this option shall
be exercisable for a period of one year following the date of death or
disability of the Participant, provided  that this option shall be
exercisable only to the extent that this option was exercisable by the
Participant on the date of his or her death or disability, and further provided
that this option shall not be exercisable after the Final Exercise Date.

 

2

 

(e)                                  Discharge
for Cause.  If the Participant,
prior to the Final Exercise Date, is discharged by the Company for Cause, the
right to exercise this option shall terminate immediately upon the effective
date of such discharge.  “Cause” shall
mean:  (i) conviction of any felony or
any crime involving moral turpitude or dishonesty; (ii) participation in a
fraud or act of dishonesty against the Company (or, if applicable, a successor
corporation to the Company); (iii) willful and material breach of the Company’s
policies (or, if applicable, the policies of a successor corporation to the
Company); (iv) intentional and material damage to the Company’s property (or,
if applicable, the property of a successor corporation to the Company); or (v)
material breach of such Participant’s non-disclosure, non-competition or other
similar agreement with the Company (or, if applicable, a successor corporation
to the Company). 

 

4.                                       Withholding.

 

No Shares will be issued
pursuant to the exercise of this option unless and until the Participant pays
to the Company, or makes provision satisfactory to the Company for payment of,
any federal, state or local withholding taxes required by law to be withheld in
respect of this option.

 

5.                                       Non-transferability
of Option.

 

This option may not be
sold, assigned, transferred, pledged or otherwise encumbered by the
Participant, either voluntarily or by operation of law, except by will or the
laws of descent and distribution and, during the lifetime of the Participant,
this option shall be exercisable only by the Participant.  

 

6.                                       Provisions
of the Plan.  

 

This option is subject to
the provisions of the Plan, a copy of which is furnished to the Participant
with this option.  

 

IN WITNESS WHEREOF, the
Company has caused this option to be executed under its corporate seal by its
duly authorized officer.  This option
shall take effect as a sealed instrument. 

 

	
   

  	
  The Medicines Company

  
	
   

  	
   

  
	
  Dated: 

  	
   

  	
   

  	
  By:

  	
   

  	
   

  
	
   

  	
  Name:

  	
  Steven Koehler

  
	
   

  	
  Title:

  	
  CFO

  
							

 

3

 

PARTICIPANT’S
ACCEPTANCE

 

The undersigned hereby
accepts the foregoing option and agrees to the terms and conditions
thereof.  The undersigned hereby
acknowledges receipt of a copy of the Company’s 1998 Stock Incentive Plan
Prospectus.

 

	
   

  	
  PARTICIPANT:

  
	
   

  	
   

  
	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
  [Name]

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
  Date:

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
   

  
	
   

  	
  Address:

  	
   

  	
   

  
					

 

4Exhibit 10.75

 

GILEAD
SCIENCES, INC.

2004
EQUITY INCENTIVE PLAN

AS
AMENDED JULY 29, 2004

 

1.                                       Purpose
of the Plan.  The purpose of this
Plan is to provide incentives to attract, retain and motivate eligible persons
whose present and potential contributions are important to the success of the
Company by offering them an opportunity to participate in the Company’s future
performance.  If this Plan is approved
by stockholders at the 2004 annual meeting of stockholders, it will replace the
Gilead Sciences, Inc. 1991 Stock Option Plan and the Gilead Sciences, Inc. 1995
Non-Employee Directors’ Stock Option Plan, no further option grants will be
made under those plans, and the remaining shares available for issuance under
those plans will be available for issuance under this Plan.

 

2.                                       Definitions.  As used herein, the following definitions
shall apply:

 

(a)                                  “Administrator”
means the Board or any of the Committees appointed to administer the Plan.

 

(b)                                 “Affiliate”
and “Associate” shall have the respective meanings ascribed to such
terms in Rule 12b-2 promulgated under the Exchange Act.

 

(c)                                  “Applicable Acceleration Period”
means:  (i) 24 months, in the case of
the Chief Executive Officer, (ii) 18 months, in the case of an Executive Vice
President or Senior Vice President, and (iii) 12 months, in the case of all
other Grantees.

 

(d)                                 “Applicable
Laws” means the legal requirements relating to the Plan and the Awards
under applicable provisions of federal securities laws, state corporate and
securities laws, the Code, the rules of any applicable stock exchange or
national market system, and the rules of any non-U.S. jurisdiction applicable
to Awards granted to residents therein.

 

(e)                                  “Award”
means the grant of an Option, SAR, Dividend Equivalent Right, Restricted Stock,
Performance Unit, Performance Share, Phantom Share, or other right or benefit
under the Plan.

 

(f)                                    “Award
Agreement” means the written agreement evidencing the grant of an Award
executed by the Company and the Grantee, including any amendments thereto.

 

(g)                                 “Board”
means the Board of Directors of the Company.

 

(h)                                 “Cause”
means with respect to the termination by the Company or a Related Entity of the
Grantee’s Continuous Active Service, that such termination is for “Cause” as
such term is expressly defined in a then-effective written agreement between
the Grantee and the Company or such Related Entity, or in the absence of such
then-effective written agreement and definition, is based on, in the
determination of the Administrator, the Grantee’s:  (i) performance of any act or failure to perform any act in bad
faith and to the detriment of the Company or a Related Entity; (ii) dishonesty,

 

 

intentional misconduct, material violation of any applicable Company or
Related Entity policy, or material breach of any agreement with the Company or
a Related Entity; or (iii) commission of a crime involving dishonesty, breach
of trust, or physical or emotional harm to any person.

 

(i)                                     “Change
in Control” means a change in ownership or control of the Company effected
through any of the following transactions:

 

(i)                                     a
dissolution or liquidation of the Company;

 

(ii)                                  a
merger or consolidation in which the Company is not the surviving corporation;

 

(iii)                               a
reverse merger in which the Company is the surviving corporation but the shares
of the Company’s common stock outstanding immediately preceding the merger are
converted by virtue of the merger into other property, whether in the form of
securities, cash or otherwise; or

 

(iv)                              any
other capital reorganization in which more than 50% of the shares of the
Company entitled to vote are exchanged.

 

(j)                                     “Code”
means the Internal Revenue Code of 1986, as amended.

 

(k)                                  “Committee”
means any committee composed of members of the Board appointed by the Board to
administer the Plan.

 

(l)                                     “Common
Stock” means the common stock of the Company.

 

(m)                               “Company”
means Gilead Sciences, Inc., a Delaware corporation.

 

(n)                                 “Consultant”
means any person including an advisor, who is engaged by the Company or any
Related Entity to render services to the Company or such Related Entity and who
is compensated for such services, provided that the term “Consultant” shall not
include Directors who are paid only a director’s fee by the Company or who are
not otherwise compensated by the Company for their services as Directors.  The term “Consultant” shall include a member
of the Board of Directors of a Related Entity.

 

(o)                                 “Continuous
Active Service” means that the provision of services to the Company or a
Related Entity in any capacity of Employee, Director or Consultant is not
interrupted or terminated.  In
jurisdictions requiring notice in advance of an effective termination as an
Employee, Director or Consultant, Continuous Active Service shall be deemed
terminated upon the actual cessation of providing services to the Company or a
Related Entity notwithstanding any required notice period that must be
fulfilled before a termination as an Employee, Director or Consultant can be
effective under Applicable Laws. 
Continuous Active Service shall not be considered interrupted in the
case of (i) any approved leave of absence or (ii) transfers among the Company,
any Related Entity, or any successor, in any capacity of Employee, Director or
Consultant.

 

 

Continuous Active Service shall be considered interrupted in the case
of any change in status or capacity as an Employee, Director or Consultant
(except as otherwise provided in the Award Agreement or authorized by the
Board).  The Board or the chief
executive officer of the Company, in that party’s sole discretion, may determine
whether Continuous Active Service shall be considered interrupted in the case
of any leave of absence approved by the Board or the chief executive officer of
the Company including sick leave, military leave, or any other personal leave.  For purposes of each Incentive Stock Option
granted under the Plan, if such leave exceeds 90 days, and reemployment upon
expiration of such leave is not guaranteed by statute or contract, then the
Incentive Stock Option shall be treated as a Nonstatutory Stock Option on the
day three months and one day following the expiration of such 90 day period.

 

(p)                                 “Covered
Employee” means an Employee who is a “covered employee” under
Section 162(m)(3) of the Code.

 

(q)                                 “Director”
means a member of the Board or the board of directors of any Related Entity.

 

(r)                                    “Dividend
Equivalent Right” means a right entitling the Grantee to compensation
measured by dividends paid with respect to Common Stock.

 

(s)                                  “Domestic
Partner” means a person who meets and continues to meet all of the criteria
detailed in the Gilead Sciences Affidavit of Domestic Partnership when the
Domestic Partnership has been internally registered with the Company by filing
with the Company an original, properly completed, notarized Gilead Sciences
Affidavit of Domestic Partnership.

 

(t)                                    “Employee”
means any person, including an Officer or Director, who is in the employ of the
Company or any Related Entity, subject to the control and direction of the
Company or any Related Entity as to both the work to be performed and the
manner and method of performance. 
Neither service as a Director nor payment of a director’s fee by the
Company or a Related Entity shall not be sufficient to constitute “employment”
by the Company.

 

(u)                                 “Exchange
Act” means the Securities Exchange Act of 1934, as amended.

 

(v)                                 “Fair
Market Value” means, as of any date, the value of Common Stock determined
as follows:

 

(i)                                     If
the Common Stock is listed on any established stock exchange or a national
market system, including without limitation The Nasdaq National Market or The
Nasdaq SmallCap Market of The Nasdaq Stock Market, its Fair Market Value shall
be the closing sales price for such stock (or the closing bid, if no sales were
reported) as quoted on such system or exchange (or the exchange with the
greatest volume of trading in common stock) on the last market trading day
prior to the date of determination (or, if no closing sales price or closing
bid was reported on that date, as applicable, on the last trading date such
closing sales price or closing bid was reported),

 

 

as reported in The Wall Street Journal or such other source as the
Board deems reliable; or

 

(ii)                                  If
the Common Stock is regularly quoted on an automated quotation system
(including the OTC Bulletin Board) or by a recognized securities dealer, but
selling prices are not reported, the Fair Market Value of a Share of Common
Stock shall be the mean between the high bid and high asked prices for the
Common Stock on the last market trading day prior to the date of determination
(or, if no such prices were reported on that date, on the last date such prices
were reported), as reported in The Wall Street Journal or such other source as
the Board deems reliable; or

 

(iii)                               In
the absence of an established market for the Common Stock of the type described
in (i) and (ii), above, the Fair Market Value thereof shall be determined by
the Board in good faith.

 

(w)                               “Grantee”
means an Employee, Director or Consultant who receives an Award under the Plan.

 

(x)                                   “Immediate
Family” means any child, stepchild, grandchild, parent, stepparent,
grandparent, spouse, former spouse, sibling, niece, nephew, mother-in-law,
father-in-law, son-in law, daughter-in-law, brother-in-law, or sister-in-law,
including adoptive relationships, Domestic Partner, a trust in which these
persons (or the Grantee) have more than 50% of the beneficial interest, a
foundation in which these persons (or the Grantee) control the management of
assets, and any other entity in which these persons (or the Grantee) own more
than fifty percent (50%) of the voting interests

 

(y)                                 “Incentive
Stock Option” means an Option intended to qualify as an incentive stock
option within the meaning of Section 422 of the Code and the regulations
promulgated thereunder.

 

(z)                                   “Nonstatutory
Stock Option” means an Option not intended to qualify as an Incentive Stock
Option.

 

(aa)                            “Officer”
means a person who is an officer of the Company or a Related Entity within the
meaning of Section 16 of the Exchange Act and the rules and regulations
promulgated thereunder.

 

(bb)                          “Option”
means an option to purchase Shares pursuant to an Award Agreement granted under
the Plan.

 

(cc)                            “Parent”
means a “parent corporation”, whether now or hereafter existing, as defined in
Section 424(e) of the Code.

 

(dd)                          “Performance-Based
Compensation” means compensation qualifying as “performance-based
compensation” under Section 162(m) of the Code.

 

(ee)                            “Performance
Shares” means Shares or an Award denominated in Shares which may be earned
in whole or in part upon attainment of performance criteria

 

 

established by the Administrator.

 

(ff)                                “Performance
Units” means an Award denominated in U.S. dollars which may be earned in
whole or in part based upon attainment of performance criteria established by
the Administrator and which may be settled for cash, Shares or other securities
or a combination of cash, Shares or other securities as established by the
Administrator.

 

(gg)                          “Phantom
Share” means an Award denominated in Shares in which the Grantee has the
right to receive an amount equal to the value of a specified number of Shares
over a specified period of time and which will be payable in cash or Shares as
established by the Administrator.

 

(hh)                          “Plan”
means this Gilead Sciences, Inc. 2004 Equity Incentive Plan.

 

(ii)                                  “Related
Entity” means any Parent or Subsidiary of the Company and any business,
corporation, partnership, limited liability company or other entity in which
the Company or a Parent or a Subsidiary of the Company holds a substantial
ownership interest, directly or indirectly.

 

(jj)                                  “Restricted
Stock” means Shares or an Award denominated in Shares issued under the Plan
to the Grantee for such consideration, if any, and subject to such restrictions
on transfer, rights of first refusal, repurchase provisions, forfeiture provisions,
and other terms and conditions as established by the Administrator.

 

(kk)                            “Rule
16b-3” means Rule 16b-3 promulgated under the Exchange Act or any successor
thereto, as in effect when discretion is being exercised with respect to the
Plan.

 

(ll)                                  “SAR”
means a stock appreciation right entitling the Grantee to Shares or cash
compensation, as established by the Administrator, measured by appreciation in
the value of Common Stock.

 

(mm)                      “Share”
means a share of the Common Stock.

 

(nn)                          “Subsidiary”
means a “subsidiary corporation”, whether now or hereafter existing, as defined
in Section 424(f) of the Code.

 

3.                                       Stock
Subject to the Plan.

 

(a)                                  Subject
to the provisions of Section 10 below, the maximum aggregate number of
Shares which may be issued pursuant to all Awards (including, without
limitation, Restricted Stock, Performance Shares, Options, SARs, Dividend
Equivalent Rights, and Phantom Shares) is 3,600,000 Shares, plus the number of
shares previously authorized for issuance under the Gilead Sciences, Inc. 1991
Stock Option Plan and the Gilead Sciences, Inc. 1995 Non-Employee Directors’
Stock Option Plan which are not required to be issued upon the exercise of
options under those plans

 

 

outstanding on May 25, 2004. 
Notwithstanding the foregoing, no more than 200,000 of such Shares may
be issued pursuant to all Awards of Restricted Stock, Performance Shares, and
Phantom Shares, in total.  The Shares to
be issued pursuant to Awards may be authorized, but unissued, or reacquired
Common Stock.  Performance Units that by
their terms may only be settled in cash shall not reduce the maximum aggregate
number of shares that may be issued under the Plan.

 

(b)                                 Any
Shares covered by an Award (or portion of an Award) which is forfeited,
canceled or expires (whether voluntarily or involuntarily) shall be deemed not
to have been issued for purposes of determining the maximum aggregate number of
Shares which may be issued under the Plan. 
Shares that actually have been issued under the Plan pursuant to an
Award shall not be returned to the Plan and shall not become available for
future issuance under the Plan, except that if unvested Shares are forfeited,
or repurchased by the Company at the lower of their original purchase price or
their Fair Market Value at the time of repurchase, such Shares shall become
available for future grant under the Plan.

 

4.                                       Administration
of the Plan.

 

(a)                                  Plan
Administrator:

 

(i)                                     Administration
with Respect to Directors and Officers. 
With respect to grants of Awards to Directors or Employees who are also
Officers or Directors of the Company, the Plan shall be administered by (A) the
Board or (B) a Committee designated by the Board, which Committee shall be
constituted in such a manner as to satisfy the Applicable Laws and to permit
such grants and related transactions under the Plan to be exempt from
Section 16(b) of the Exchange Act in accordance with Rule 16b-3.  Once appointed, such Committee shall
continue to serve in its designated capacity until otherwise directed by the
Board.

 

(ii)                                  Administration
With Respect to Consultants and Other Employees.  With respect to grants of Awards to Employees or Consultants who
are neither Directors nor Officers of the Company, the Plan shall be
administered by (A) the Board or (B) a Committee designated by the Board, which
Committee shall be constituted in such a manner as to satisfy the Applicable
Laws.  Once appointed, such Committee
shall continue to serve in its designated capacity until otherwise directed by the
Board.  The Board may authorize one or
more Officers to grant such Awards and may limit such authority as the Board
determines from time to time.

 

(iii)                               Administration
With Respect to Covered Employees. 
Notwithstanding the foregoing, grants of Awards to any Covered Employee
intended to qualify as Performance-Based Compensation shall be made only by a
Committee (or subcommittee of a Committee) which is comprised solely of two or
more Directors eligible to serve on a committee making Awards qualifying as
Performance-Based Compensation.  In the case
of such Awards granted to Covered Employees, references to the “Administrator”
or to a “Committee” shall be deemed to be references to such Committee or
subcommittee.

 

 

(b)                                 Powers
of the Administrator.  Subject to
Applicable Laws and the provisions of the Plan (including any other powers
given to the Administrator hereunder), and except as otherwise provided by the
Board, the Administrator shall have the authority, in its discretion:

 

(i)                                     to
select the Employees, Directors and Consultants to whom Awards may be granted
from time to time hereunder;

 

(ii)                                  to
determine whether and to what extent Awards are granted hereunder;

 

(iii)                               to
determine the number of Shares or the amount of other consideration to be
covered by each Award granted hereunder;

 

(iv)                              to
approve forms of Award Agreements for use under the Plan;

 

(v)                                 to
determine the terms and conditions of any Award granted hereunder;

 

(vi)                              to
amend the terms of any outstanding Award granted under the Plan, provided that
(A) any amendment that would adversely affect the Grantee’s rights under an
outstanding Award shall not be made without the Grantee’s written consent, (B)
the reduction of the exercise price of any Option awarded under the Plan shall
be subject to stockholder approval as provided in Section 7(b), and (C)
canceling an Option at a time when its exercise price exceeds the Fair Market
Value of the underlying Shares, in exchange for another Option, Restricted
Stock, or other Award shall be subject to stockholder approval as provided in Section 7(b),
unless the cancellation and exchange occurs in connection with a Change in
Control as provided in Section 11;

 

(vii)                           to
construe and interpret the terms of the Plan and Awards, including without
limitation, any notice of award or Award Agreement, granted pursuant to the
Plan;

 

(viii)                        to
establish additional terms, conditions, rules or procedures to accommodate the
rules or laws of applicable non-U.S. jurisdictions and to afford Grantees
favorable treatment under such rules or laws; provided, however, that no Award
shall be granted under any such additional terms, conditions, rules or
procedures with terms or conditions which are inconsistent with the provisions
of the Plan; and

 

(ix)                                to
take such other action, not inconsistent with the terms of the Plan, as the
Administrator deems appropriate.

 

(c)                                  Indemnification.  In addition to such other rights of
indemnification as they may have as members of the Board or as Officers or
Employees of the Company or a Related Entity, members of the Board and any Officers
or Employees of the Company or a Related Entity to whom authority to act for
the Board,

 

 

the Administrator or the Company is delegated shall be defended and
indemnified by the Company to the extent permitted by law on an after-tax basis
against all reasonable expenses (including attorneys’ fees), actually and
necessarily incurred in connection with the defense of any claim,
investigation, action, suit or proceeding, or in connection with any appeal
therein, to which they or any of them may be a party by reason of any action
taken or failure to act under or in connection with the Plan, or any Award
granted hereunder, and against all amounts paid by them in settlement thereof
(provided such settlement is approved by the Company) or paid by them in satisfaction
of a judgment in any such claim, investigation, action, suit or proceeding,
except in relation to matters as to which it shall be adjudged in such claim,
investigation, action, suit or proceeding that such person is liable for gross
negligence, bad faith or intentional misconduct; provided, however, that within
30 days after the institution of such claim, investigation, action, suit or
proceeding, such person shall offer to the Company, in writing, the opportunity
at the Company’s expense to handle and defend the same.

 

5.                                       Eligibility.  Awards other than Incentive Stock Options
may be granted to Employees, Directors and Consultants.  Incentive Stock Options may be granted only
to Employees of the Company or a Parent or a Subsidiary of the Company.  An Employee, Director or Consultant who has
been granted an Award may, if otherwise eligible, be granted additional
Awards.  Awards may be granted to such
Employees, Directors or Consultants who are residing in non-U.S. jurisdictions
as the Administrator may determine.

 

6.                                       Terms
and Conditions of Awards.

 

(a)                                  Type
of Awards.  The Administrator is
authorized under the Plan to award any type of arrangement to an Employee,
Director or Consultant that is not inconsistent with the provisions of the Plan
and that by its terms involves or might involve the issuance of (i) Shares,
(ii) cash or (iii) an Option, a SAR, or similar right with a fixed or variable
price related to the Fair Market Value of the Shares and with an exercise or
conversion privilege related to the passage of time, the occurrence of one or
more events, or the satisfaction of performance criteria or other
conditions.  Such awards include,
without limitation, Options, SARs, Restricted Stock, Dividend Equivalent
Rights, Performance Units, Performance Shares, or Phantom Shares. An Award may
consist of one such security or benefit, or two or more of them in any
combination or alternative.

 

(b)                                 Designation
of Award.  Each Award shall be
designated in the Award Agreement.  In
the case of an Option, the Option shall be designated as either an Incentive
Stock Option or a Nonstatutory Stock Option. 
However, notwithstanding such designation, to the extent that the
aggregate Fair Market Value of Shares subject to Options designated as
Incentive Stock Options which become exercisable for the first time by a
Grantee during any calendar year (under all plans of the Company or any Parent
or Subsidiary of the Company) exceeds $100,000, such excess Options, to the
extent of the Shares covered thereby in excess of the foregoing limitation,
shall be treated as Nonstatutory Stock Options.  For this purpose, Incentive Stock Options shall be taken into
account in the order in which they were granted, and the Fair Market Value of the

 

 

Shares shall be determined as of the grant date of the relevant Option.

 

(c)                                  Conditions
of Award.  Subject to the terms of
the Plan, the Administrator shall determine the provisions, terms, and
conditions of each Award including, but not limited to, the Award vesting
schedule, repurchase provisions, rights of first refusal, forfeiture
provisions, form of payment (cash, Shares, or other consideration) upon
settlement of the Award, payment contingencies, and satisfaction of any
performance criteria.  The performance
criteria established by the Administrator may be based on any one of, or
combination of, the following: (i) revenue, (ii) achievement of specified
milestones in the discovery and development of one or more of the Company’s
products, (iii) achievement of specified milestones in the commercialization of
one or more of the Company’s products, (iv) achievement of specified milestones
in the manufacturing of one or more of the Company’s products, (v) expense
targets, (vi) personal management objectives, (vii) share price (including, but
not limited to, growth measures and total shareholder return), (viii) earnings
per share, (ix) operating efficiency, (x) operating margin, (xi) gross margin,
(xii) return measures (including, but not limited to, return on assets,
capital, equity, or sales), (xiii) net sales growth, (xiv) productivity ratios,
(xv) operating income, (xvi) net operating profit, (xvii) net earnings or net
income (before or after taxes), (xviii) cash flow (including, but not limited
to, operating cash flow, free cash flow, and cash flow return on capital),
(xix) earnings before or after interest, taxes, depreciation, and/or
amortization, (xx) economic value added, (xxi) market share, (xxii) customer
satisfaction, (xxiii) working capital targets, and (xxiv) other measures of performance
selected by the Administrator.   
Partial achievement of the specified criteria may result in a payment or
vesting corresponding to the degree of achievement as specified in the Award
Agreement.

 

(d)                                 Acquisitions
and Other Transactions.  The Administrator
may issue Awards under the Plan in settlement, assumption or substitution for,
outstanding awards or obligations to grant future awards in connection with the
Company or a Related Entity acquiring another entity, an interest in another
entity or an additional interest in a Related Entity whether by merger, stock
purchase, asset purchase or other form of transaction.

 

(e)                                  Deferral
of Award Payment.  The Administrator
may establish one or more programs under the Plan to permit selected Grantees
the opportunity to elect to defer receipt of consideration upon exercise of an
Award, satisfaction of performance criteria, or other event that absent the
election would entitle the Grantee to payment or receipt of Shares or other
consideration under an Award.  The
Administrator may establish the election procedures, the timing of such
elections, the mechanisms for payments of, and accrual of interest or other
earnings, if any, on amounts, Shares or other consideration so deferred, and
such other terms, conditions, rules and procedures that the Administrator deems
advisable for the administration of any such deferral program.

 

(f)                                    Separate
Programs.  The Administrator may
establish one or more separate programs under the Plan for the purpose of
issuing particular forms of Awards to one or more classes of Grantees on such
terms and conditions as determined by the Administrator from time to time.

 

 

(g)                                 Individual
Limitations on Awards.  The maximum
number of Shares with respect to which Options and/or SARs may be granted to
any Grantee in any fiscal year of the Company shall be 1,000,000 Shares.  The maximum number of Shares with respect to
which Restricted Stock, Performance Shares, or Phantom Shares, in the
aggregate, may be granted to any Grantee in any fiscal year of the Company
shall be 100,000 Shares.  In connection
with a Grantee’s (i) commencement of Continuous Active Service or (ii)
promotion, a Grantee may be granted Options and/or SARs for up to an additional
500,000 Shares or Restricted Stock, Performance Shares, or Phantom Shares, in
the aggregate, for up to an additional 50,000 shares which shall not count
against the limit set forth in the preceding sentence.  The foregoing limitations shall be adjusted
proportionately in connection with any change in the Company’s capitalization
pursuant to Section 10, below.  The
value of all Awards denominated in U.S. dollars granted in any single calendar
year to any Participant shall not exceed $7,000,000.  For this purpose, the value of an Award denominated in U.S.
dollars shall be determined on the date of grant without regard to any
conditions imposed on the Award.  To the
extent required by Section 162(m) of the Code or the regulations
thereunder, in applying the foregoing limitations with respect to a Grantee, if
any Awards are canceled, the canceled Awards shall continue to count against
the maximum number of Shares with respect to which Awards may be granted to the
Grantee.  For this purpose, the
repricing of an Option (or in the case of a SAR, the base amount on which the
stock appreciation is calculated is reduced to reflect a reduction in the Fair
Market Value of the Common Stock), if such repricing is approved by the
stockholders of the Company, shall be treated as the cancellation of the
existing Option or SAR and the grant of a new Option or SAR.  If the vesting or receipt of Shares under
the Award is deferred to a later date, any amount (whether denominated in
Shares or U.S. dollars) paid in addition to the original number of Shares
subject to the Award will not be treated as an increase in the number of Shares
subject to the Award if the additional amount is based either on a reasonable
rate of interest or on one or more predetermined actual investments such that
the amount payable by the Company at the later date will be based on the actual
rate of return of a specific investment (including any decrease as well as any
increase in the value of an investment).

 

(h)                                 Early
Exercise.  The Award Agreement may,
but need not, include a provision whereby the Grantee may elect at any time
while an Employee, Director or Consultant to exercise any part or all of the
Award prior to full vesting of the Award. 
Any unvested Shares received pursuant to such exercise may be subject to
a repurchase right in favor of the Company or a Related Entity or to any other
restriction the Administrator determines to be appropriate.

 

(i)                                     Term
of Award.  The term of each Award
shall be the term stated in the Award Agreement, provided, however, that the
term of an Award shall be no more than ten years from the date of grant
thereof.  However, in the case of an
Incentive Stock Option granted to a Grantee who, at the time the Option is
granted, owns stock representing more than 10% of the voting power of all
classes of stock of the Company or any Parent or Subsidiary of the Company, the
term of the Incentive Stock Option shall be five years from the date of grant
thereof or such shorter term as may be provided in the Award Agreement.

 

 

(j)                                     Transferability
of Awards.  Incentive Stock Options
may not be sold, pledged, assigned, hypothecated, transferred, or disposed of
in any manner other than by will or by the laws of descent or distribution and
may be exercised, during the lifetime of the Grantee, only by the Grantee.  Other Awards shall be transferable by will
and by the laws of descent and distribution, and during the lifetime of the
Grantee, by gift or pursuant to a domestic relations order to members of the
Grantee’s Immediate Family to the extent and in the manner determined by the Administrator.  Notwithstanding the foregoing, the Grantee
may designate a beneficiary of the Grantee’s Award in the event of the
Grantee’s death on a beneficiary designation form provided by the
Administrator.

 

(k)                                  Time
of Granting Awards.  The date of
grant of an Award shall for all purposes be the date on which the Administrator
makes the determination to grant such Award, or such later date as is
determined by the Administrator.

 

7.                                       Award
Exercise or Purchase Price; Consideration and Taxes.

 

(a)                                  Exercise
or Purchase Price.  The exercise or
purchase price, if any, for an Award shall be as follows:

 

(i)                                     In
the case of an Incentive Stock Option:

 

(A)                              granted
to an Employee who, at the time of the grant of such Incentive Stock Option
owns stock representing more than 10% of the voting power of all classes of
stock of the Company or any Parent or Subsidiary of the Company, the per Share
exercise price shall be not less than 110% of the Fair Market Value per Share
on the date of grant; or

 

(B)                                granted
to any Employee other than an Employee described in the preceding paragraph,
the per Share exercise price shall be not less than 100% of the Fair Market
Value per Share on the date of grant.

 

(ii)                                  In
the case of a Nonstatutory Stock Option, the per Share exercise price shall be
not less than 100% of the Fair Market Value per Share on the date of grant.

 

(iii)                               In
the case of a SAR, the base amount on which the stock appreciation is
calculated shall be not less than 100% of the Fair Market Value per Share on
the date of grant.

 

(iv)                              In
the case of other Awards, such price as is determined by the Administrator.

 

(v)                                 Notwithstanding
the foregoing provisions of this Section 7(a), in the case of an Award
issued pursuant to Section 6(d), above, the exercise or purchase price for
the Award shall be determined in accordance with the provisions of the relevant
instrument evidencing the agreement to issue such Award.

 

(b)                                 No
Authority to Reprice.  Without the
consent of stockholders of

 

 

the Company, the Board shall have no authority to effect (i) the
repricing of any outstanding Options under the Plan and/or (ii) the
cancellation of any outstanding Options under the Plan and the grant in
substitution therefor of new Options under the Plan covering the same or
different numbers of shares of Common Stock.

 

(c)                                  Consideration.  Subject to Applicable Laws, the
consideration to be paid for the Shares to be issued upon exercise or purchase
of an Award including the method of payment, shall be determined by the
Administrator (and, in the case of an Incentive Stock Option, shall be
determined at the time of grant).  In
addition to any other types of consideration the Administrator may determine,
the Administrator is authorized to accept as consideration for Shares issued
under the Plan the following, provided that the portion of the consideration
equal to the par value of the Shares must be paid in cash or other legal
consideration permitted by the Delaware General Corporation Law:

 

(vi)                              cash;

 

(vii)                           check;

 

(viii)                        surrender
of Shares or delivery of a properly executed form of attestation of ownership
of Shares as the Administrator may require (including withholding of Shares
otherwise deliverable upon exercise of the Award) which have a Fair Market
Value on the date of surrender or attestation equal to the aggregate exercise
price of the Shares as to which said Award shall be exercised, provided,
however, that Shares acquired under the Plan or any other equity compensation
plan or agreement of the Company must have been held by the Grantee for a
period of more than six months;

 

(ix)                                with
respect to Options, payment through a traditional broker-dealer sale and
remittance procedure pursuant to which the Grantee (A) shall provide written
instructions to a Company designated brokerage firm to effect the immediate
sale of some or all of the purchased Shares and remit to the Company sufficient
funds to cover the aggregate exercise price payable for the purchased Shares
and (B) shall provide written directives to the Company to deliver the certificates
for the purchased Shares directly to such brokerage firm in order to complete
the sale transaction;

 

(x)                                   with
respect to Options, payment through an internet-based broker-dealer sale and
remittance procedure pursuant to which the Grantee (A) shall establish and
maintain an account with the internet-based broker-dealer to effect the sale of
some or all of the purchased Shares and ensure that such account contains
sufficient funds to cover the aggregate exercise price payable for the
purchased Shares and (B) shall execute the transaction with the internet-based
broker-dealer who will then cause the purchased Shares to be deposited into the
Grantee’s account in order to complete the sale transaction; or

 

(xi)                                any
combination of the foregoing methods of payment.

 

(d)                                 Taxes.  No Shares shall be delivered under the Plan
to any Grantee or other person until such Grantee or other person has made
arrangements acceptable to

 

 

the Administrator for the satisfaction of any federal, state, local or
non-U.S. income and employment tax withholding obligations, including, without
limitation, obligations incident to the receipt of Shares or the disqualifying
disposition of Shares received on exercise of an Incentive Stock Option.  Upon exercise of an Award the Company shall
withhold or collect from Grantee an amount sufficient to satisfy such tax
obligations.

 

8.                                       Exercise
of Award.

 

(a)                                  Procedure
for Exercise; Rights as a Stockholder.

 

(i)                                     Any
Award granted hereunder shall be exercisable at such times and under such conditions
as determined by the Administrator under the terms of the Plan and specified in
the Award Agreement.  Notwithstanding
any other provision of the Plan to the contrary, except with respect to a
maximum of 5% of the Shares authorized for issuance under Section 3(a),
any Awards of Restricted Stock which vest on the basis of the Grantee’s
Continuous Active Service with the Company or a Related Entity shall not
provide for vesting which is any more rapid than annual pro rata vesting over a
three-year period and any Awards of Restricted Stock which provide for vesting
upon the attainment of performance goals shall provide for a performance period
of at least 12 months.

 

(ii)                                  An
Award shall be deemed to be exercised when written notice of such exercise has
been given to the Company or its designee in accordance with the terms of the
Award by the person entitled to exercise the Award and full payment for the
Shares with respect to which the Award is exercised, including, to the extent
selected, use of the broker-dealer sale and remittance procedure to pay the
purchase price as provided in Section 7(c)(iv).

 

(b)                                 Exercise
of Award Following Termination of Continuous Active Service.

 

(i)                                     An
Award may not be exercised after the termination date of such Award set forth
in the Award Agreement and may be exercised following the termination of a
Grantee’s Continuous Active Service only to the extent provided in the Award
Agreement.

 

(ii)                                  Where
the Award Agreement permits a Grantee to exercise an Award following the termination
of the Grantee’s Continuous Active Service for a specified period, the Award
shall terminate to the extent not exercised on the last day of the specified
period or the last day of the original term of the Award, whichever occurs
first.

 

(iii)                               Any
Award designated as an Incentive Stock Option to the extent not exercised
within the time permitted by law for the exercise of Incentive Stock Options
following the termination of a Grantee’s Continuous Active Service shall
convert automatically to a Nonstatutory Stock Option and thereafter shall be
exercisable as such to the extent exercisable by its terms for the period
specified in the Award Agreement.

 

 

9.                                       Conditions
Upon Issuance of Shares.

 

(a)                                  Shares
shall not be issued pursuant to the exercise of an Award unless the exercise of
such Award and the issuance and delivery of such Shares pursuant thereto shall
comply with all Applicable Laws, and shall be further subject to the approval
of counsel for the Company with respect to such compliance.

 

(b)                                 As
a condition to the exercise of an Award, the Company may require the person
exercising such Award to represent and warrant at the time of any such exercise
that the Shares are being purchased only for investment and without any present
intention to sell or distribute such Shares if, in the opinion of counsel for
the Company, such a representation is required by any Applicable Laws.

 

10.                                 Adjustments
Upon Changes in Capitalization.  If
any change is made in the Common Stock subject to the Plan, or subject to any
Award (through merger, consolidation, reorganization, recapitalization, stock
dividend, dividend in property other than cash, stock split, liquidating
dividend, combination of shares, exchange of shares, change in corporate
structure or otherwise), the Plan will be appropriately adjusted in the
class(es) and maximum number of shares subject to the Plan pursuant to
Section 3(a), and the maximum number of shares subject to award to any
person during any calendar year pursuant to Section 6(g), and the outstanding
Awards (other than an Award of Restricted Stock that is outstanding at the time
of the event described in this paragraph) will be appropriately adjusted in the
classes(es) and the number of shares and price per Share subject to such
outstanding Awards, including any price required to be paid for Restricted
Stock not yet outstanding at the time of the event described in this paragraph

 

11.                                 Change
in Control.

 

(a)                                  Effect
of Change in Control on Awards.  In
the event of a Change in Control, then, at the sole discretion of the Board and
to the extent permitted by applicable law: 
(i) any surviving corporation shall assume any Awards outstanding under
the Plan or shall substitute similar Awards for those outstanding under the
Plan, (ii) the time during which such Awards may be exercised shall be
accelerated and the Awards terminated if not exercised prior to the Change in
Control, or (iii) such Awards shall continue in full force and effect.

 

(b)                                 Acceleration
of Award Upon Change in Control. Notwithstanding any other provisions of
this Plan to the contrary, if a Change in Control occurs and if within one
month before or within the Applicable Acceleration Period after the date of
such Change in Control (1) the Continuous Active Service of an Employee or Consultant
terminates due to an involuntary termination (not including death or
Disability) without Cause (as such term is defined below) or a voluntary
termination by the Grantee due to Constructive Termination (as such term is
defined below) or (2) the Continuous Active Service of a Director terminates,
then the vesting and exercisability of all Awards held by such Grantee shall be
accelerated, or any reacquisition or repurchase rights held by the Company with
respect to an Award shall lapse, as follows. 
With respect to those Awards held by a Grantee at the time of such
termination, 100% of the unvested Shares covered

 

 

by such Awards shall vest and become exercisable (or reacquisition or
repurchase rights held by the Company shall lapse with respect to 100% of the
Shares still subject to such rights, as appropriate) as of the date of such
termination.

 

(c)                                  Definition
of “Cause”.  For the purposes of
Section 11(b) only, “Cause” means (i) conviction of, a guilty plea with
respect to, or a plea of non contendere to a charge that a Grantee
has committed a felony under the laws of the United States or of any state or a
crime involving moral turpitude, including, but not limited to, fraud, theft,
embezzlement or any crime that results in or is intended to result in personal
enrichment at the expense of the Company or a Related Entity; (ii) material
breach of any agreement entered into between the Grantee and the Company or a
Related Entity that impairs the Company’s or the Related Entity’s interest
therein; (iii) willful misconduct, significant failure of the Grantee to
perform the Grantee’s duties, or gross neglect by the Grantee of the Grantee’s
duties; or (iv) engagement in any activity that constitutes a material conflict
of interest with the Company or a Related Entity.

 

(d)                                 Definition
of “Constructive Termination”.  For
purposes of Section 11(b) only, “Constructive Termination” means the
occurrence of any of the following events or conditions:  (i) (A) a change in the Grantee’s status,
title, position or responsibilities (including reporting responsibilities)
which represents an adverse change from the Grantee’s status, title, position
or responsibilities as in effect at any time within 90 days preceding the date
of a Change in Control or within the Applicable Acceleration Period after the
date of a Change in Control; (B) the assignment to the Grantee of any duties or
responsibilities which are inconsistent with the Grantee’s status, title,
position or responsibilities as in effect at any time within 90 days preceding
the date of a Change in Control or at any time within the Applicable
Acceleration Period after the Change in Control; or (C) any removal of the
Grantee from or failure to reappoint or reelect the Grantee to any of such
offices or positions, except in connection with the termination of the
Grantee’s Continuous Active Service for Cause, as a result of the Grantee’s
Disability or death or by the Grantee other than as a result of Constructive
Termination; (ii) a reduction in the Grantee’s annual base compensation or any
failure to pay the Grantee any compensation or benefits to which the Grantee is
entitled within five days of the date due; (iii) the Company’s requiring the
Grantee to relocate to any place outside a 50 mile radius of the Grantee’s
current work site, except for reasonably required travel on the business of the
Company or a Related Entity which is not materially greater than such travel
requirements prior to the Change in Control; (iv) the failure by the Company to
(A) continue in effect (without reduction in benefit level and/or reward
opportunities) any material compensation or employee benefit plan in which the
Grantee was participating at any time within 90 days preceding the date of a
Change in Control or at any time within the Applicable Acceleration Period
after the Change in Control, unless such plan is replaced with a plan that
provides substantially equivalent compensation or benefits to the Grantee, or
(B) provide the Grantee with compensation and benefits, in the aggregate, at
least equal (in terms of benefit levels and/or reward opportunities) to those
provided for under each other employee benefit plan, program and practice in
which the Grantee was participating at any time within 90 days preceding the
date of a Change in Control or at any within the Applicable Acceleration Period
after the Change in Control; (v) any material breach by the Company of any
provision of an agreement between the Company

 

 

and the Grantee, whether pursuant to this Plan or otherwise, other than
a breach which is cured by the Company within 15 days following notice by the
Grantee of such breach; of (vi) the failure of the Company to obtain an
agreement, satisfactory to the Grantee, from any successors and assigns to
assume and agree to perform the obligations created under this Plan.

 

(e)                                  Effect
of Acceleration on Incentive Stock Options.  Any Incentive Stock Option accelerated under this Section 11
in connection with a Change in Control shall remain exercisable as an Incentive
Stock Option under the Code only to the extent the $100,000 dollar limitation
of Section 422(d) of the Code is not exceeded.  To the extent such dollar limitation is exceeded, the excess
Options shall be treated as Nonstatutory Stock Options.

 

12.                                 Effective
Date and Term of Plan.  The Plan
shall become effective upon its approval by the stockholders of the
Company.  It shall continue in effect
for a term of ten years unless sooner terminated.  Subject to Applicable Laws, Awards may be granted under the Plan
upon its becoming effective.

 

13.                                 Amendment,
Suspension or Termination of the Plan.

 

(a)                                  The
Board may at any time amend, suspend or terminate the Plan; provided, however,
that no such amendment shall be made without the approval of the Company’s
stockholders to the extent such approval is required by NASD Marketplace Rule
4350(i)(1)(A), Section 422 of the Code and regulations promulgated
thereunder, or any other Applicable Laws, or if such amendment would change any
of the provisions of Section 4(b)(vi) or this Section 13(a).

 

(b)                                 No
Award may be granted during any suspension of the Plan or after termination of
the Plan.

 

(c)                                  No
suspension or termination of the Plan (including termination of the Plan under
Section 12, above) shall adversely affect any rights under Awards already
granted to a Grantee.

 

14.                                 Reservation
of Shares.

 

(a)                                  The
Company, during the term of the Plan, will at all times reserve and keep
available such number of Shares as shall be sufficient to satisfy the
requirements of the Plan.

 

(b)                                 The
inability of the Company to obtain authority from any regulatory body having
jurisdiction, which authority is deemed by the Company’s counsel to be
necessary to the lawful issuance and sale of any Shares hereunder, shall
relieve the Company of any liability in respect of the failure to issue or sell
such Shares as to which such requisite authority shall not have been obtained.

 

15.                                 No
Effect on Terms of Employment/Consulting Relationship.  The Plan shall not confer upon any Grantee
any right with respect to the Grantee’s Continuous

 

 

Active Service, nor shall it interfere in any way with his or her right
or the right of the Company or any Related Entity to terminate the Grantee’s
Continuous Active Service at any time, with or without Cause, and with or
without notice.  The ability of the
Company or any Related Entity to terminate the employment of a Grantee who is
employed at will is in no way affected by its determination that the Grantee’s
Continuous Active Service has been terminated for Cause for the purposes of
this Plan.

 

16.                                 No
Effect on Retirement and Other Benefit Plans.  Except as specifically provided in a retirement or other benefit
plan of the Company or a Related Entity, Awards shall not be deemed
compensation for purposes of computing benefits or contributions under any
retirement plan of the Company or a Related Entity, and shall not affect any
benefits under any other benefit plan of any kind or any benefit plan
subsequently instituted under which the availability or amount of benefits is
related to level of compensation.  The
Plan is not a “Pension Plan” or “Welfare Plan” under the Employee Retirement
Income Security Act of 1974, as amended.

 

17.                                 Unfunded
Obligation.  Grantees shall have the
status of general unsecured creditors of the Company.  Any amounts payable to Grantees pursuant to the Plan shall be
unfunded and unsecured obligations for all purposes, including, without
limitation, Title I of the Employee Retirement Income Security Act of 1974, as
amended.  Neither the Company nor any
Related Entity shall be required to segregate any monies from its general
funds, or to create any trusts, or establish any special accounts with respect
to such obligations.  The Company shall
retain at all times beneficial ownership of any investments, including trust
investments, which the Company may make to fulfill its payment obligations
hereunder.  Any investments or the
creation or maintenance of any trust or any Grantee account shall not create or
constitute a trust or fiduciary relationship between the Administrator, the
Company or any Related Entity and a Grantee, or otherwise create any vested or
beneficial interest in any Grantee or the Grantee’s creditors in any assets of
the Company or a Related Entity.  The
Grantees shall have no claim against the Company or any Related Entity for any
changes in the value of any assets that may be invested or reinvested by the
Company with respect to the Plan.

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