Document:

Exhibit 10.8

 

OphthaliX
Inc.

 

STOCK OPTION AGREEMENT FORM

  

This Grant of Stock
Option is hereby offered to the undersigned (the “Optionee”) with respect to the following option grant (the
“Option”) to purchase shares of the Common Stock of OphthaliX Inc., a Delaware corporation (the “Company”):

 

	Optionee:	 	Kornberg – Lorch Living Trust
	 	 	 
	Grant Date:	 	February 2, 2012
	 	 	 
	Exercise Price:	 	$2.00 US
	 	 	 
	Number of Option Shares:	 	235,000
	 	 	 
	Expiration Date: 	 	February 2, 2022
	 	 	 
	Date Exercisable:	 	See Vesting Schedule
	 	 	 
	Vesting Schedule:	 	Subject to 36 months vesting;  1/12th  of the options vest shall vest on March 31, 2012, and the remaining options shall vest 1/12th on the last day of each calendar quarter thereafter until fully vested.
	 	 	 
	Special Terms or Conditions:	 	none

 

Optionee understands
and agrees that the Option is granted subject to and in accordance with the terms of the Company’s 2012 Stock Incentive Plan,
as amended (the “Plan”). Optionee further agrees to be bound by the terms of the Plan and the terms of the Option
grant as set forth in this Stock Option Agreement Form.

 

Optionee hereby acknowledges
receipt of a copy of the Plan in the form attached hereto as Exhibit A. All capitalized terms in this Grant form shall have the
meaning assigned to them in this form or in the attached Plan.

 

Optionee acknowledges
receipt of a copy of the Company’s 10(a) Prospectus attached hereto as Exhibit B which sets forth certain terms and conditions
of this grant. By signing this form, Optionee agrees and consents to access the most recent annual report of the Company on Form
10-K and any subsequent reports on Form 10-Q or 8-K, as well as any amendments thereto, via the Internet in lieu of receiving paper
copies of these documents with this grant. These documents may be accessed at the following website by typing in the name of the
Company where indicated: http://www.sec.gov/edgar/searchedgar/companysearch.html. The Optionee acknowledges and accepts the costs
associated with this electronic access, such as usage charges for Internet service providers.

 

    	 

    	 

    

 

Assuming that you are
in agreement with the terms of this Stock Option Agreement Form, please sign your name in the space indicated below.

 

	 	OphthaliX Inc.
	 	 	 
	 	By: 	/s/ Barak Singer         /s/ Pnina Fishman
	 	 	 
	 	Title: 	CEO

 

AGREED:

  

	/s/ Roger Kornberg	 	 
	Optionee’s Signature	 	 
	 	 	 	 
	Address:  	345
    Walsh Rd.	 	 
	 	Atherton CA 94027	 	 
	 	 	 	 
	Date: 	June 12	, 2013	 

  

		Exhibit A	2012 Stock Incentive Plan

		Exhibit B	10(a) Prospectus dated January 1, 2013

 

    	2Exhibit 10.9

 

Made as of the 28 day of April, 2013

 

	BETWEEN:	OphthaliX
    Inc.
	 	A company incorporated in the State of Delaware
	 	(hereinafter
    the “Company”)
	 	 
	 	on the one part    
	 	 
	AND:	Gil Ben Menachem
	 	I.D. 022935761
	 	Of 4 HaHadas St. Petach Tikvah, 49321, Israel
	 	(hereinafter the “Optionee”)
	 	on the other part

  

WHEREAS, on February 2, 2012
the shareholders of the Company approved the 2012 Stock Incentive Plan, a copy of which is attached as Exhibit A
hereto (the "Plan"), on January 29, 2013 the Board of Directors of the Company has approved the Israeli Annex
to the Plan to enable the grant of Options under Section 102 of the Israeli Tax Ordinance ("Section 102"), a copy
of which is attached as Exhibit A hereto, forming an integral part hereof (the “ISOP”; the Plan
and the ESOP shall collectively be referred to herein as the "ESOP"), and on April 22, 2013 the Board of Director
of the Company has resolved to grant to the Optionee a Time Based Option to purchase up to 469,854 Common Stock of the Company
and a Success Based Option to purchase up to 469,854 Common Stock of the Company (collectively, the "Shares")
in accordance with the terms of the ESOP; and

 

WHEREAS, the
Optionee has agreed to such grant, subject to all the terms and conditions as set forth in the ESOP and as provided herein;

  

NOW, THEREFORE, it is agreed as
follows:

 

1.        Preamble
and Definitions

 

1.1           The
preamble to this agreement constitutes an integral part hereof.

 

1.2           Unless
otherwise defined herein (including in Exhibit B), capitalized terms used herein
shall have the meaning ascribed to them in the ESOP.

 

2.        Grant of Options

 

2.1
     The Company hereby grants to the Optionee the number of Options as set forth in Exhibit B
hereto, each Option shall be exercisable for one Share, upon payment of the Purchase Price as set forth in Exhibit B,
subject to the terms and the conditions as set forth in the ESOP and as provided herein.

 

2.2           The
Optionee is aware that the Company intends in the future to issue additional shares and to grant additional options to various
entities and individuals, as the Company in its sole discretion shall determine.

 

    	 

    	 

    

  

3.        Period
of Option and Conditions of Exercise 

 

3.1           The
terms of this Option Agreement shall commence on the Date of Grant and terminate at the Expiration Date, or at the time at which
the Option expires pursuant to the terms of the ESOP or pursuant to this Option Agreement. 

 

3.2           Options
may be exercised only to purchase whole Shares, and in no case may a fraction of a Share be purchased. If any fractional Share
would be deliverable upon exercise, such fraction shall be rounded up one-half or less, or otherwise rounded down, to the nearest
whole number.

 

4.        Adjustments

 

Notwithstanding anything
to the contrary in the ESOP and in addition thereto, in any such Reorganization Event as described in the ESOP, the Vesting Dates
shall be accelerated so that any unvested Option shall be immediately vested in full as of the date which is ten (10) days prior
to the effective date of the Reorganization Event, and the Board shall notify the Optionee that the unexercised Options are fully
exercisable for a period of ten (10) days from the date of such notice, and that any unexercised Options shall terminate upon the
expiration of such period.

 

5.        Term
and Exercise of Options

 

5.1           Options
shall be exercised by the Optionee by giving written notice and the payment of the purchase price to the Company, in such form
and method as may be determined by the Company and when applicable, by the trustee appointed under Section 102 (the "Trustee")
in accordance with the requirements of Section 102, which exercise shall be effective upon receipt of such notice by the Company
and the payment of the Purchase Price at its principal office. The notice shall specify the number of Shares with respect to which
the Option is being exercised.

 

5.2           Options,
to the extent not previously exercised, shall terminate forthwith upon the earlier of: (i) the date set forth in Exhibit
B to the Option Agreement; and (ii) the expiration of any extended period in any of the events set forth in Section 5.5
below.

 

5.3           The
Options may be exercised by the Optionee in whole at any time or in part from time to time, to the extent that the Options become
vested and exercisable, prior to the Expiration Date, and provided that, subject to the provisions of Section 5.5 below, the Optionee
is employed by or providing services to the Company or any of its Affiliates, at all times during the period beginning with the
granting of the Option and ending upon the date of exercise.

 

5.4           Subject
to the provisions of Section 5.5 below, in the event of termination of Optionee’s employment or services, with the Company
or any of its Affiliates, all Options granted to such Optionee will immediately expire. A notice of termination of employment or
service shall be deemed to constitute termination of employment or service.

 

5.5           Notwithstanding
anything to the contrary hereinabove, an Option may be exercised after the date of termination of Optionee's employment or services
with the Company or any Affiliate during an additional period of time beyond the date of such termination, but only with respect
to the number of Vested Options at the time of such termination according to the Vesting Dates of the Options, if:

 

(i) termination is
without Cause, in which event any Vested Option still in force and unexpired may be exercised within a period of ninety (90) days
after the date of such termination; or-

 

    	 

    	 

    

 

(ii) termination
is the result of death or disability of the Optionee, in which event any Vested Option still in force and unexpired may be exercised
within a period of twelve (12) months after the date of such termination; or -

 

(iii) prior to the
date of such termination, the Committee shall authorize an extension of the terms of all or part of the Vested Options beyond the
date of such termination for a period not to exceed the period during which the Options by their terms would otherwise have been
exercisable.

 

For avoidance of
any doubt, if termination of employment or service is for Cause, any outstanding unexercised Option, will immediately expire and
terminate, and the Optionee shall not have any right in connection to such outstanding Options.

 

5.6           To
avoid doubt, the holders of Options shall not have any of the rights or privileges of shareholders of the Company in respect of
any Shares purchasable upon the exercise of any part of an Option, nor shall they be deemed to be a class of shareholders or creditors
of the Company for purpose of the operation of any applicable corporate laws, until registration of the Optionee as holder of such
Shares in the Company’s register of shareholders upon exercise of the Options in accordance with the provisions of the ESOP.

 

5.7           Any
form of Option Agreement authorized by the ESOP may contain such other provisions as the Committee may, from time to time, deem
advisable.

 

5.8      Notwithstanding
anything to the contrary herein above, in the event of termination of Optionee's employment or service with the Company or any
Affiliate, when the employee continues to provide services (or vice versa) to the Company or any Affiliate, the Options granted
to such Optionee shall not be affected by such change in the Optionee’s status, and the employee will be allowed to keep
the Options pursuant to its original terms. 

 

6.          Vesting;
Period of Exercise

 

Subject
to the provisions of the ESOP, Options shall vest and become exercisable according to the Vesting Dates set forth in Exhibit
B hereto, provided that the Optionee is employed by or provides services to the Company and/or
its Affiliates on the applicable Vesting Date.

 

All
unexercised Options granted to the Optionee shall terminate and shall no longer be exercisable on the Expiration Date.

 

7.        Exercise
of Options 

 

7.1           Options
may be exercised in accordance with the provisions of the ESOP.

 

7.2           In
order for the Company to issue Shares upon the exercise of any of the Options, the Optionee hereby agrees to sign any and all documents
required by any applicable law and/or by the Company's incorporation documents.

 

7.3           Until
the consummation of an IPO, any Shares acquired upon the exercise of Options shall be voted by an irrevocable proxy, attached as
Exhibit C hereto.

 

    	 

    	 

    

 

7.4           The
Company shall not be obligated to issue any Shares upon the exercise of an Option if such issuance, in the opinion of the Company,
might constitute a violation by the Company of any provision of law.

 

8.        Restrictions
on Transfer of Options and Shares 

 

8.1           The
transfer of Options and the transfer of Shares to be issued upon exercise of the Options shall be subject to the limitations set
forth in the ESOP and in the Company’s incorporation documents and any shareholders’ agreement to which the holders
of ordinary shares of the Company are bound.

 

8.2           With
respect to any Approved 102 Option, subject to the provisions of Section 102 and any rules or regulation or orders or procedures
promulgated thereunder, an Optionee shall not be entitled to sell or release from trust any Share received upon the exercise of
an Approved 102 Option and/or any share received subsequently following any realization of rights, including without limitation,
bonus shares, until the lapse of the holding period required under Section 102 of the Ordinance.

 

8.3           With
respect to Unapproved 102 Option, if the Optionee ceases to be employed by the Company or any Affiliate, the Optionee shall extend
to the Company and/or its Affiliate a security or guarantee for the payment of tax due at the time of sale of Shares, all in accordance
with the provisions of Section 102 and the rules, regulation or orders promulgated thereunder.

 

8.4           The
Optionee acknowledges that in the event Company's shares shall be registered for trading in any public market, the Optionee’s
right to sell Shares may be subject to limitations (including a lock-up period), as will be requested by the Company or its underwriters,
and the Optionee unconditionally agrees and accepts any such limitations.

 

The Optionee acknowledges
that in order to enforce the above restriction, the Company may impose stop-transfer instructions with respect to the exercised
Shares.

 

8.5           The
Optionee shall not dispose of any Shares in transactions which violate, in the opinion of the Company, any applicable laws, rules
and regulations.

 

8.6           The
Optionee agrees that the Company shall have the authority to endorse upon the certificate or certificates representing the Shares
such legends referring to the foregoing restrictions, and any other applicable restrictions as it may deem appropriate (which do
not violate the Optionee's rights according to this Option Agreement).

 

9.          Taxes;
Indemnification

 

9.1           Any
tax consequences arising from the grant or exercise of any Option, from the payment for Shares covered thereby or from any other
event or act (of the Company and/or its Affiliates, the Trustee or the Optionee), hereunder, shall be borne solely by the Optionee.
The Company and/or its Affiliates and/or the Trustee shall withhold taxes according to the requirements under the applicable laws,
rules, and regulations, including withholding taxes at source. Furthermore, the Optionee hereby agrees to indemnify the Company
and/or its Affiliates and/or the Trustee and hold them harmless against and from any and all liability for any such tax
or interest or penalty thereon, including without limitation, liabilities relating to the necessity to withhold, or to have withheld,
any such tax from any payment made to the Optionee.

 

    	 

    	 

    

 

9.2           The
Optionee hereby acknowledges that he is familiar with the provisions of Section 102 and the regulations and rules promulgated thereunder,
including without limitations the type of Option granted hereunder and the tax implications applicable to such grant. The Optionee
accepts the provisions of the trust agreement signed between the Company and the Trustee, attached as Exhibit D hereto,
and agrees to be bound by its terms.

 

9.3           The
receipt of the Options and the acquisition of the Shares to be issued upon the exercise of the Options may result in tax consequences.
THE OPTIONEE IS ADVISED TO CONSULT A TAX ADVISER WITH RESPECT TO THE TAX CONSEQUENCES OF RECEIVING OR EXERCISING THIS OPTION OR
DISPOSING OF THE SHARES.

 

9.4           The
Optionee will not be entitled to receive from the Company and/or the Trustee any Shares allocated or issued upon the exercise of
Options prior to the full payments of the Optionee’s tax liabilities arising from Options which were granted to him and/or
Shares issued upon the exercise of Options. For the avoidance of doubt, neither the Company nor the Trustee shall be required to
release any share certificate to the Optionee until all payments required to be made by the Optionee have been fully satisfied.

 

10.         Miscellaneous

 

10.1         No
Obligation to Exercise Options. The grant and acceptance of these Options imposes no obligation on the Optionee to exercise
it.

 

10.2         Confidentiality.
The Optionee shall regard the information in this Option Agreement and its exhibits attached hereto as confidential information
and the Optionee shall not reveal its contents to anyone except when required by law or for the purpose of gaining legal or tax
advice.

 

10.3         Continuation
of Employment or Service. Neither the ESOP nor this Option Agreement shall impose any obligation on the Company or an Affiliate
to continue the Optionee’s employment or service and nothing in the ESOP or in this Option Agreement shall confer upon the
Optionee any right to continue in the employ or service of the Company and/or an Affiliate or restrict the right of the Company
or an Affiliate to terminate such employment or service at any time.

 

10.4         Entire
Agreement. Subject to the provisions of the ESOP, to which this Option Agreement is subject, this Option Agreement, together
with the exhibits hereto, constitute the entire agreement between the Optionee and the Company with respect to Options granted
hereunder, and supersedes all prior agreements, understandings and arrangements, oral or written, between the Optionee and the
Company with respect to the subject matter hereof.

 

10.5         Failure
to Enforce - Not a Waiver. The failure of any party to enforce at any time any provisions of this Option Agreement or the ESOP
shall in no way be construed to be a waiver of such provision or of any other provision hereof.

 

10.6         Provisions
of the ESOP. The Options provided for herein are granted pursuant to the ESOP and said Options and this Option Agreement are
in all respects governed by the ESOP and subject to all of the terms and provisions of the ESOP. Any interpretation of this Option
Agreement will be made in accordance with the ESOP but in the event there is any contradiction between the provisions of this Option
Agreement and the ESOP, the provisions of the Option Agreement will prevail.

 

    	 

    	 

    

 

10.7         Binding
Effect. The ESOP and this Option Agreement shall be binding upon the heirs, executors, administrators and successors of the
parties hereof.

 

10.8         Notices.
All notices or other communications given or made hereunder shall be in writing and shall be delivered or mailed by registered
mail or delivered by email or facsimile with written confirmation of receipt to the Optionee and/or to the Company at the addresses
shown on the letterhead above, or at such other place as the Company may designate by written notice to the Optionee. The Optionee
is responsible for notifying the Company in writing of any change in the Optionee’s address, and the Company shall be deemed
to have complied with any obligation to provide the Optionee with notice by sending such notice to the address indicated below. 

 

	OphthaliX Inc.: 	 	 
	 	 	 
	Name: Barak Singer	 	Name: Pnina Fishman 
	 	 	 
	Position: CEO	 	Position: Chairman
	 	 	 
	Signature: 	/s/ Barak Singer	 	Signature: 	/s/ Pnina Fishman

 

I, the undersigned, hereby acknowledge
receipt of a copy of the ESOP and accept the Options subject to all of the terms and provisions thereof. I have reviewed the ESOP
and this Option Agreement in its entirety, have had an opportunity to obtain the advice of counsel prior to executing this Option
Agreement, and fully understand all provisions of this Option Agreement. I agree to notify the Company upon any change in the residence
address indicated above.

 

	April 28, 2013	/s/ Gil Ben-Menachem	 
	 	 	 
	Date	Gil Ben Menachem	 

 

    	 

    	 

    

 

	Attachments:
	 	 	 
	Exhibit A:	 	OphthaliX 2012 Stock Incentive Plan/Israeli Annex to the OphthaliX StockIncentive Plan
	 	 	 
	Exhibit B:	 	Terms of the Option
			
		 	
	Exhibit C:		Proxy
		 	 
			
	Exhibit D:		Trust Agreement between the Company and the Trustee

 

    	 

    	 

    

 

EXHIBIT B 

 

TERMS OF THE OPTION 

 

	Name of the Optionee:	Gil Ben Menachem
	Date of Grant:	April 22, 2013 (the "Date of Grant")
	Designation:	
        üApproved
        102 Option:

        Capital Gain Option (CGO)

        ƒ
        Unapproved 102 Option

         

        ƒ
        3(i) Option

         

	1.          Number of Options granted:	
        Time Based Options - 469,854

        Success Based Options - 469,854

         

	2.          Purchase Price:	US$1.1757 (average of the 30 days prior to the Board resolution) (the "Purchase Price")
	3.          Vesting Dates as follows:	 

 

	TIME BASED OPTIONS
	Number of Options	 	 	Vesting Date
	 	39,155	 	 	March 31, 2013
	 	39,155	 	 	June 30, 2013
	 	39,155	 	 	September 30, 2013
	 	39,155	 	 	December 31, 2013
	 	39,155	 	 	March 31, 2014
	 	39,155	 	 	June 30, 2014
	 	39,154	 	 	September 30, 2014
	 	39,154	 	 	December 31, 2014
	 	39,154	 	 	March 31, 2015
	 	39,154	 	 	June 30, 2015
	 	39,154	 	 	September 30, 2015
	 	39,154	 	 	December 31, 2015

 

	SUCCES BASED OPTIONS
	Number of Options	 	 	Vesting Date
	 	156,618	 	 	upon the commencement of the trading of OphthaliX's securities on Nasdaq or NYSE MKT LLC (formerly known as Amex).
	 	156,618	 	 	vest upon completion of an out-license transaction in relation to any product of OphthaliX.
	 	156,618	 	 	upon the commencement of a phase 3 clinical trial of CF-101 for Glaucoma (and in the unlikely event that the phase 2 trial is unsuccessful, then OphthaliX's Board shall allocate a different milestone).

 

	4.          Expiration Date:	April 21, 2023 (the "Expiration Date")

 

    	 

    	 

    

 

EXHIBIT C 

 

PROXY 

 

The undersigned, as record holder of securities
of OphthaliX Inc. (the “Company”) described below, hereby irrevocably appoints the CEO of the Company, as my
proxy to attend all shareholders’ meetings and to vote, execute consents, and otherwise represent me with respect to exercised
shares (i.e. options exercised into shares pursuant to the OphthaliX 2012 Stock Incentive Plan, and any annexes thereto) in the
same manner and with the same effect as if the undersigned were personally present at any such meeting or voting such securities
or personally acting on any matters submitted to shareholders for approval or consent.

 

This proxy is made pursuant the OphthaliX
2012 Stock Incentive Plan approved by the stockholders on February 6, 2012.

 

The Shares shall be voted by the proxy
holder in the same proportion as the votes of the other shareholders of the Company.

 

This proxy is irrevocable as it may effect
rights of third parties.

 

The irrevocable proxy will remain in full
force and effect until the consummation of an IPO, upon which it will terminate automatically.

 

This proxy shall be signed exactly as
the shareholder’s name appears on his share certificate. Joint shareholders must each sign this proxy. If signed by an attorney
in fact, the Power of Attorney must be attached. 

 

	/s/ Gil Ben Menachem	 	30/4/13
	Gil Ben Menachem	 	Date

 

    	 

    	 

    

 

EXHIBIT D

 

TRUST NOTE 

 

This Trust Note (the "Trust Note") entered into this
__ day of January 2013

By and between:

 

	S.G.S Trusts Ltd.	 
	4 Berkowitz St.	 
	Tel Aviv, 61180 (the "Trustee")	on the one part

 

Ophtalix Inc.

(the "Issuing Company")

 

EyeFite Ltd.

10Bareket St.

Petach Tikva

 

CanFite Biopharma Ltd.

10Bareket St.

Petach Tikva

 

(together shall be referred to as the "Employer Companies")
           on the second part

 

Whereas          on the ___ day of January 2013, the Issuing Company
adopted an employee option plan, as defined in section 102 to the Tax Ordinance (the "Plan"); and

 

Whereas          according to the Plan, the Issuing Company will
issue from time to time, shares or rights to shares to employees including to the employees of the Employer Companies in Israel,
such issuance will be through a trustee; and

 

Whereas          In accordance with the Plan, shares will be issued
to the Trustee to hold in trust until the end of the period as defined in the Tax Ordinance, Income Tax Ordinance (Tax breaks allocation
of shares to employees)- 2003 (the "Rules"), in the Plan and this Trust Note; and

 

Whereas         The Employer Companies have chosen S.G.S Trusts Ltd.,
to act as the Trustee with respect to the Plan, and S.G.S Trusts Ltd., expressed her consent to act as a Trustee for the Employer
Companies and their employees in Israel.

?

 

NOW THEREFORE IT HAS BEEN AGREED, DECLARED AND STIPULATED BETWEEN
THE PARTIES AS FOLLOWS:

 

1.          The
introduction to this trust Note form an integral part thereof.

 

2.          According
to the Plan the company's shares will not be issued to any of the Employer Companies employees, rather will be issued in the name
of the Trustee and will be held by him until the end of the period, as defined in section 102 to the Tax Ordinance.

 

    	 

    	 

    

 

3.          Until
all applicable tax payments were paid in accordance with section 7 to the Rules, the shares will not be transferable, assignable,
pledged, foreclosed or any lien with respect thereto, and no power of attorney or transfer deed shall be provided with respect
to the shares, whether its validity is immediate or to a future date, except a transfer by virtue of will or law.

In case of transfer by virtue of will or law, the provisions
of section 102 to the Tax Ordinance and the Rules will apply on the transferees of the employee.

 

4.          At
any time after the end of the period, each employee will be entitled to demand that the Trustee transfer the shares held on his
behalf to his name, provided however, that the Trustee will not transfer such shares until all applicable tax was paid according
to section 102 of the Tax Ordinance and the Rules (the "Applicable Tax"), and the Trustee received the applicable assessor's
confirmation.

 

5.          If
according to the Plan the employee will be issued rights to purchase shares, or will be issued with respect to the shares, bonus
shares, they will be issued in the name of the Trustee. The employee will be entitled to instruct the Trustee to exercise the rights
or the bonus shares following the end of the period as defined in the Plan. The shares subject to the rights will be issued to
the Trustee in accordance with section 2 to the Rules, and the provisions of the Plan will apply, including, selection of a tax
track and the provisions of this Trust Note, however the time frame until the end of the period will be calculated from of the
date of the actual share issuance in connection with the rights and bonus shares.

 

6.          The
company hereby commits to the Trustee that she will not issue any shares to the Employer Companies employees in Israel as part
of the Plan, unless the employee stated that its aware of the provisions of section 102 to the Tax Ordinance and the applicable
tax track, and has provided his written consent to the provisions of this Trust Note, and of his commitment not to exercise the
shares before the end of the period, as defined in 102 to the Tax Ordinance.

 

IN WITNESS WHEREOF THE PARTIES HAVE SIGNED BELOW:

 

	/s/ Pnina Fishman	 	/s/ Pnina Fishman /s/ Ilan Cohn	 	/s/ S.G.S Trusts Ltd.
	Eyefite Ltd.	 	CanFite Biopharma Ltd.	 	S.G.S Trusts Ltd.

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