Document:

agle-ex41_8.htm

Exhibit 4.1

AEGLEA BIOTHERAPEUTICS, INC.

FORM OF WARRANT TO PURCHASE COMMON STOCK

Number of Shares: [    ]

(subject to adjustment)

 

	
 
	
 
	
 

	
Warrant No. [    ]
	
  
	
Original Issue Date: [    ], 2020

Aeglea BioTherapeutics, Inc., a Delaware corporation (the “Company”), hereby certifies that, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, [    ] or its registered assigns (the “Holder”), is entitled, subject to the terms set forth below, to purchase from the Company up to a total of [    ] shares of common stock, $0.0001 par value per share (the “Common Stock”), of the Company (each such share, a “Warrant Share” and all such shares, the “Warrant Shares”) at an exercise price per share equal to $0.0001 per share (as adjusted from time to time as provided in Section 9 herein, the “Exercise Price”) upon surrender of this Warrant to Purchase Common Stock (including any Warrants to Purchase Common Stock issued in exchange, transfer or replacement hereof, the “Warrant”) at any time and from time to time on or after the date hereof (the “Original Issue Date”), subject to the following terms and conditions:

1. Definitions. For purposes of this Warrant, the following terms shall have the following meanings:

(a) “Affiliate” means any Person directly or indirectly controlled by, controlling or under common control with, a Holder, as such terms are used in and construed under Rule 405 under the Securities Act, but only for so long as such control shall continue.

(b) “Commission” means the United States Securities and Exchange Commission.

(c) “Closing Sale Price” means, for any security as of any date, the last trade price for such security on the Principal Trading Market for such security, as reported by Bloomberg L.P., or, if such Principal Trading Market begins to operate on an extended hours basis and does not designate the last trade price, then the last trade price of such security prior to 4:00 P.M., New York City time, as reported by Bloomberg L.P., or if the security is not listed for trading on a national securities exchange or other trading market on the relevant date, the last quoted bid price for the security in the over-the-counter market on the relevant date as reported by OTC Markets Group Inc. (or a similar organization or agency succeeding to its functions of reporting prices). If the Closing Sale Price cannot be calculated for a security on a particular date on any of the foregoing bases, the Closing Sale Price of such security on such date shall be the fair market value as mutually determined by the Company and the Holder. If the Company and the Holder are unable to agree upon the fair market value of such security, then the Board of Directors of the Company shall use its good faith judgment to determine the fair market value. The Board of Directors’ determination shall be binding upon all parties absent demonstrable error. All such determinations shall be appropriately adjusted for any stock dividend, stock split, stock combination or other similar transaction during the applicable calculation period.

(d) “Principal Trading Market” means the national securities exchange or other trading market on which the Common Stock is primarily listed on and quoted for trading, which, as of the Original Issue Date, shall be the Nasdaq Global Market.

(e) “Registration Statement” means the Company’s Registration Statement on Form S-3 (File No. 333-228967), declared effective on February 13, 2019.

(f) “Securities Act” means the Securities Act of 1933, as amended.

(g) “Trading Day” means any weekday on which the Principal Trading Market is open for trading. If the Common Stock is not listed or admitted for trading, “Trading Day” means any day except any Saturday, any Sunday, any day which is a federal legal holiday in the United States or any day on which banking institutions in New York City are authorized or required by law or other governmental action to close.

(h) “Transfer Agent” means American Stock Transfer and Trust Company, LLC, the Company’s transfer agent and registrar for the Common Stock, and any successor appointed in such capacity.

 

2. Issuance of Securities; Registration of Warrants. The Warrant, as initially issued by the Company, is offered and sold pursuant to the Registration Statement. As of the Original Issue Date, the Warrant Shares are issuable under the Registration Statement. Accordingly, the Warrant and, assuming issuance pursuant to the Registration Statement or an exchange meeting the requirements of 

 

 

Section 3(a)(9) of the Exchange Act as in effect on the Original Issue Date, the Warrant Shares are not “restricted securities” under Rule 144 promulgated under the Securities Act. The Company shall register ownership of this Warrant, upon records to be maintained by the Company for that purpose (the “Warrant Register”), in the name of the record Holder (which shall include the initial Holder or, as the case may be, any assignee to which this Warrant is assigned hereunder) from time to time. The Company may deem and treat the registered Holder of this Warrant as the absolute owner hereof for the purpose of any exercise hereof or any distribution to the Holder, and for all other purposes, absent actual notice to the contrary.

3. Registration of Transfers. Subject to compliance with all applicable securities laws, the Company shall, or will cause its Transfer Agent to, register the transfer of all or any portion of this Warrant in the Warrant Register, upon surrender of this Warrant, and payment for all applicable transfer taxes (if any). Upon any such registration or transfer, a new warrant to purchase Common Stock in substantially the form of this Warrant (any such new warrant, a “New Warrant”) evidencing the portion of this Warrant so transferred shall be issued to the transferee, and a New Warrant evidencing the remaining portion of this Warrant not so transferred, if any, shall be issued to the transferring Holder. The acceptance of the New Warrant by the transferee thereof shall be deemed the acceptance by such transferee of all of the rights and obligations in respect of the New Warrant that the Holder has in respect of this Warrant. The Company shall, or will cause its Transfer Agent to, prepare, issue and deliver at the Company’s own expense any New Warrant under this Section 3. Until due presentment for registration of transfer, the Company may treat the registered Holder hereof as the owner and holder for all purposes, and the Company shall not be affected by any notice to the contrary.

4. Exercise and Duration of Warrants.

(a) All or any part of this Warrant shall be exercisable by the registered Holder in any manner permitted by this Warrant at any time and from time to time on or after the Original Issue Date.

(b) The Holder may exercise this Warrant by delivering to the Company (i) an exercise notice, in the form attached as Schedule 1 hereto (the “Exercise Notice”), completed and duly signed, and (ii) payment of the Exercise Price for the number of Warrant Shares as to which this Warrant is being exercised (which may take the form of a “cashless exercise” if so indicated in the Exercise Notice pursuant to Section 10 below). The date on which such exercise notice is delivered to the Company (as determined in accordance with the notice provisions hereof) is an “Exercise Date.” The Holder shall not be required to deliver the original Warrant in order to effect an exercise hereunder. Execution and delivery of the Exercise Notice shall have the same effect as cancellation of the original Warrant and issuance of a New Warrant evidencing the right to purchase the remaining number of Warrant Shares, if any. The Holder and any assignee, by acceptance of this Warrant, acknowledge and agree that, by reason of the provisions of this paragraph, following the purchase of a portion of the Warrant Shares hereunder, the number of Warrant Shares available for purchase hereunder at any given time may be less than the amount stated on the face hereof.

5. Delivery of Warrant Shares.

(a) Upon exercise of this Warrant, the Company shall promptly (but in no event later than three (3) Trading Days after the Exercise Date), upon the request of the Holder, credit such aggregate number of shares of Common Stock to which the Holder is entitled pursuant to such exercise to the Holder’s or its designee’s balance account with The Depository Trust Company (“DTC”) through its Deposit Withdrawal Agent Commission system, or if the Transfer Agent is not participating in the Fast Automated Securities Transfer Program (the “FAST Program”) or if the certificates are required to bear a legend regarding restriction on transferability, issue and dispatch by overnight courier to the address as specified in the Exercise Notice, a certificate, registered in the Company’s share register in the name of the Holder or its designee, for the number of shares of Common Stock to which the Holder is entitled pursuant to such exercise. The Holder, or any natural person or legal entity (each, a “Person”) so designated by the Holder to receive Warrant Shares, shall be deemed to have become the holder of record of such Warrant Shares as of the Exercise Date, irrespective of the date such Warrant Shares are credited to the Holder’s DTC account or the date of delivery of the certificates evidencing such Warrant Shares, as the case may be.

 

(b) To the extent permitted by law, the Company’s obligations to issue and deliver Warrant Shares in accordance with and subject to the terms hereof (including the limitations set forth in Section 11 below) are absolute and unconditional, irrespective of any action or inaction by the Holder to enforce the same, any waiver or consent with respect to any provision hereof, the recovery of any judgment against any Person or any action to enforce the same, or any setoff, counterclaim, recoupment, limitation or termination, or any breach or alleged breach by the Holder or any other Person of any obligation to the Company or any violation or alleged violation of law by the Holder or any other Person, and irrespective of any other circumstance that might otherwise limit such obligation of the Company to the Holder in connection with the issuance of Warrant Shares. Nothing herein shall limit the Holder’s right to pursue any other remedies available to it hereunder, at law or in equity including, without limitation, a decree of specific performance and/or injunctive relief with respect to the Company’s failure to timely deliver certificates representing shares of Common Stock upon exercise of the Warrant as required pursuant to the terms hereof.

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6. Charges, Taxes and Expenses. Issuance and delivery of certificates for shares of Common Stock upon exercise of this Warrant shall be made without charge to the Holder for any issue or transfer tax, transfer agent fee or other incidental tax or expense (excluding any applicable stamp duties) in respect of the issuance of such certificates, all of which taxes and expenses shall be paid by the Company; provided, however, that the Company shall not be required to pay any tax that may be payable in respect of any transfer involved in the registration of any certificates for Warrant Shares or the Warrants in a name other than that of the Holder or an Affiliate thereof. The Holder shall be responsible for all other tax liability that may arise as a result of holding or transferring this Warrant or receiving Warrant Shares upon exercise hereof.

7. Replacement of Warrant. If this Warrant is mutilated, lost, stolen or destroyed, the Company shall issue or cause to be issued in exchange and substitution for and upon cancellation hereof, or in lieu of and substitution for this Warrant, a New Warrant, but only upon receipt of evidence reasonably satisfactory to the Company of such loss, theft or destruction (in such case) and, in each case, a customary and reasonable indemnity and surety bond, if requested by the Company. Applicants for a New Warrant under such circumstances shall also comply with such other reasonable regulations and procedures and pay such other reasonable third-party costs as the Company may prescribe. If a New Warrant is requested as a result of a mutilation of this Warrant, then the Holder shall deliver such mutilated Warrant to the Company as a condition precedent to the Company’s obligation to issue the New Warrant.

8. Reservation of Warrant Shares. The Company covenants that it will, at all times while this Warrant is outstanding, reserve and keep available out of the aggregate of its authorized but unissued and otherwise unreserved Common Stock, solely for the purpose of enabling it to issue Warrant Shares upon exercise of this Warrant as herein provided, the number of Warrant Shares that are initially issuable and deliverable upon the exercise of this entire Warrant, free from preemptive rights or any other contingent purchase rights of persons other than the Holder (taking into account the adjustments and restrictions of Section 9). The Company covenants that all Warrant Shares so issuable and deliverable shall, upon issuance and the payment of the applicable Exercise Price in accordance with the terms hereof, be duly and validly authorized, issued and fully paid and non-assessable. The Company will take all such action as may be reasonably necessary to assure that such shares of Common Stock may be issued as provided herein without violation of any applicable law or regulation, or of any requirements of any securities exchange or automated quotation system upon which the Common Stock may be listed. The Company further covenants that it will not, without the prior written consent of the Holder, take any actions to increase the par value of the Common Stock at any time while this Warrant is outstanding.

9. Certain Adjustments. The Exercise Price and number of Warrant Shares issuable upon exercise of this Warrant are subject to adjustment from time to time as set forth in this Section 9.

(a) Stock Dividends and Splits. If the Company, at any time while this Warrant is outstanding, (i) pays a stock dividend on its Common Stock or otherwise makes a distribution on any class of capital stock issued and outstanding on the Original Issue Date and in accordance with the terms of such stock on the Original Issue Date or as amended, as described in the Registration Statement, that is payable in shares of Common Stock, (ii) subdivides its outstanding shares of Common Stock into a larger number of shares of Common Stock, (iii) combines its outstanding shares of Common Stock into a smaller number of shares of Common Stock or (iv) issues by reclassification of shares of capital stock any additional shares of Common Stock of the Company, then in each such case the Exercise Price shall be multiplied by a fraction, the numerator of which shall be the number of shares of Common Stock outstanding immediately before such event and the denominator of which shall be the number of shares of Common Stock outstanding immediately after such event. Any adjustment made pursuant to clause (i) of this paragraph shall become effective immediately after the record date for the determination of stockholders entitled to receive such dividend or distribution, provided, however, that if such record date shall have been fixed and such dividend is not fully paid on the date fixed therefor, the Exercise Price shall be recomputed accordingly as of the close of business on such record date and thereafter the Exercise Price shall be adjusted pursuant to this paragraph as of the time of actual payment of such dividends. Any adjustment pursuant to clause (ii) or (iii) of this paragraph shall become effective immediately after the effective date of such subdivision or combination.

(b) Pro Rata Distributions. If the Company, at any time while this Warrant is outstanding, distributes to all holders of Common Stock for no consideration (i) evidences of its indebtedness, (ii) any security (other than a distribution of Common Stock covered by the preceding paragraph) or (iii) rights or warrants to subscribe for or purchase any security, or (iv) cash or any other asset (in each case, a “Distribution”), other than a reclassification as to which Section 9(c) applies, then in each such case, the Holder shall be entitled to participate in such Distribution to the same extent that the Holder would have participated therein if the Holder had held the number of shares of Common Stock acquirable upon complete exercise of this Warrant (without regard to any limitations on exercise hereof, including without limitation, the ownership limitation set forth in Section 11(a) hereof) immediately before the date of which a record is taken for such Distribution, or, if no such record is taken, the date as of which the record holders of Common Stock are to be determined for the participation in such Distribution; provided, however, to the extent that the Holder’s right to participate in any such Distribution would result in the Holder exceeding the ownership limitation set forth in Section 11(a) hereof, then the Holder shall not be entitled to participate in such Distribution to such extent (or in the beneficial ownership of any Common Stock as a result of such Distribution to such extent) and the portion of such Distribution shall be held in abeyance for the benefit of the Holder until the earlier of (i) such time, if ever, as the delivery to such Holder of such portion would not result in the Holder exceeding the ownership limitation set forth in Section 11(a) hereof and (ii) such time as the Holder has exercised this Warrant.

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(c) Fundamental Transactions. If, at any time while this Warrant is outstanding (i) the Company effects any merger or consolidation of the Company with or into another Person, in which the Company is not the surviving entity and in which the stockholders of the Company immediately prior to such merger or consolidation do not own, directly or indirectly, at least 50% of the voting power of the surviving entity immediately after such merger or consolidation, (ii) the Company effects any sale to another Person of all or substantially all of its assets in one transaction or a series of related transactions, (iii) pursuant to any tender offer or exchange offer (whether by the Company or another Person), holders of capital stock tender shares representing more than 50% of the voting power of the capital stock of the Company and the Company or such other Person, as applicable, accepts such tender for payment, (iv) the Company consummates a stock purchase agreement or other business combination (including, without limitation, a reorganization, recapitalization, spin-off or scheme of arrangement) with another Person whereby such other Person acquires more than the 50% of the voting power of the capital stock of the Company (except for any such transaction in which the stockholders of the Company immediately prior to such transaction maintain, in substantially the same proportions, the voting power of such Person immediately after the transaction) or (v) the Company effects any reclassification of the Common Stock or any compulsory share exchange pursuant to which the Common Stock is effectively converted into or exchanged for other securities, cash or property (other than as a result of a subdivision or combination of shares of Common Stock covered by Section 9(a) above) (in any such case, a “Fundamental Transaction”), then following such Fundamental Transaction the Holder shall have the right to receive, upon exercise of this Warrant, the same amount and kind of securities, cash or property as it would have been entitled to receive upon the occurrence of such Fundamental Transaction if it had been, immediately prior to such Fundamental Transaction, the holder of the number of Warrant Shares then issuable upon exercise in full of this Warrant without regard to any limitations on exercise contained herein (the “Alternate Consideration”). The Company shall not effect any Fundamental Transaction in which the Company is not the surviving entity or the Alternate Consideration includes securities of another Person unless (i) the Alternate Consideration is solely cash and the Company provides for the simultaneous “cashless exercise” of this Warrant pursuant to Section 10 below or (ii) prior to or simultaneously with the consummation thereof, any successor to the Company, surviving entity or other Person (including any purchaser of assets of the Company) shall assume the obligation to deliver to the Holder such Alternate Consideration as, in accordance with the foregoing provisions, the Holder may be entitled to receive, and the other obligations under this Warrant. The provisions of this paragraph (c) shall similarly apply to subsequent transactions analogous of a Fundamental Transaction type.

 

 (d) Number of Warrant Shares. Simultaneously with any adjustment to the Exercise Price pursuant to Section 9 (including any adjustment to the Exercise Price that would have been effected but for the final sentence in this paragraph (d)), the number of Warrant Shares that may be purchased upon exercise of this Warrant shall be increased or decreased proportionately, so that after such adjustment the aggregate Exercise Price payable hereunder for the increased or decreased number of Warrant Shares shall be the same as the aggregate Exercise Price in effect immediately prior to such adjustment. Notwithstanding the foregoing, in no event may the Exercise Price be adjusted below the par value of the Common Stock then in effect.

(e) Calculations. All calculations under this Section 9 shall be made to the nearest one-hundredth of one cent or the nearest share, as applicable.

(f) Notice of Adjustments. Upon the occurrence of each adjustment pursuant to this Section 9, the Company at its expense will, at the written request of the Holder, promptly compute such adjustment, in good faith, in accordance with the terms of this Warrant and prepare a certificate setting forth such adjustment, including a statement of the adjusted Exercise Price and adjusted number or type of Warrant Shares or other securities issuable upon exercise of this Warrant (as applicable), describing the transactions giving rise to such adjustments and showing in detail the facts upon which such adjustment is based. Upon written request, the Company will promptly deliver a copy of each such certificate to the Holder and to the Company’s transfer agent.

(g) Notice of Corporate Events. If, while this Warrant is outstanding, the Company (i) declares a dividend or any other distribution of cash, securities or other property in respect of its Common Stock, including, without limitation, any granting of rights or warrants to subscribe for or purchase any capital stock of the Company or any subsidiary, (ii) authorizes or approves, enters into any agreement contemplating or solicits stockholder approval for any Fundamental Transaction or (iii) authorizes the voluntary dissolution, liquidation or winding up of the affairs of the Company, then, except if such notice and the contents thereof shall be deemed to constitute material non-public information, the Company shall deliver to the Holder a notice of such transaction at least ten (10) days prior to the applicable record or effective date on which a Person would need to hold Common Stock in order to participate in or vote with respect to such transaction; provided, however, that the failure to deliver such notice or any defect therein shall not affect the validity of the corporate action required to be described in such notice. In addition, if while this Warrant is outstanding, the Company authorizes or approves, enters into any agreement contemplating or solicits stockholder approval for any Fundamental Transaction contemplated by Section 9(c), other than a Fundamental Transaction under clause (iii) of Section 9(c), the Company shall deliver to the Holder a notice of such Fundamental Transaction at least ten (10) days prior to the date such Fundamental Transaction is consummated. Holder agrees to maintain any information disclosed pursuant to this Section 9(g) in confidence until such information is publicly available, and shall comply with applicable law with respect to trading in the Company’s securities following receipt of any such information.

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10. Payment of Cashless Exercise Price. Notwithstanding anything contained herein to the contrary, the Holder may, in its sole discretion, satisfy its obligation to pay the Exercise Price through a “cashless exercise,” in which event the Company shall issue to the Holder the number of Warrant Shares in an exchange of securities effected pursuant to Section 3(a)(9) of the Securities Act as determined as follows:

X = Y [(A-B)/A]

where:

“X” equals the number of Warrant Shares to be issued to the Holder;

“Y” equals the total number of Warrant Shares with respect to which this Warrant is then being exercised;

“A” equals the Closing Sale Price per share of Common Stock as of the Trading Day on the date immediately preceding the Exercise Date; and

“B” equals the Exercise Price per Warrant Share then in effect on the Exercise Date.

 

For purposes of Rule 144 promulgated under the Securities Act, it is intended, understood and acknowledged that the Warrant Shares issued in such a “cashless exercise” transaction shall be deemed to have been acquired by the Holder, and the holding period for the Warrant Shares shall be deemed to have commenced, on the date this Warrant was originally issued (provided that the Commission continues to take the position that such treatment is proper at the time of such exercise). In the event that the Registration Statement or another registration statement registering the issuance of Warrant shares is, for any reason, not effective at the time of exercise of this Warrant, then the Warrant may only be exercised through a cashless exercise, as set forth in this Section 10.

In no event will the exercise of this Warrant be settled in cash.

11. Limitations on Exercise.

(a) Notwithstanding anything to the contrary contained herein, the Company shall not effect any exercise of this Warrant, and the Holder shall not be entitled to exercise this Warrant for a number of Warrant Shares in excess of that number of Warrant Shares which, upon giving effect or immediately prior to such exercise, would cause (i) the aggregate number of shares of Common Stock beneficially owned by the Holder, its Affiliates and any other Persons whose beneficial ownership of Common Stock would be aggregated with the Holder’s for purposes of Section 13(d) of the Exchange Act to exceed 4.99% (the “Maximum Percentage”) of the total number of issued and outstanding shares of Common Stock of the Company following such exercise, or (ii) the combined voting power of the securities of the Company beneficially owned by the Holder and its Affiliates and any other Persons whose beneficial ownership of Common Stock would be aggregated with the Holder’s for purposes of Section 13(d) of the Exchange Act to exceed 4.99% of the combined voting power of all of the securities of the Company then outstanding following such exercise. For purposes of this Warrant, in determining the number of outstanding shares of Common Stock, the Holder may rely on the number of outstanding shares of Common Stock as reflected in (x) the Company’s most recent Form 10-Q or Form 10-K, as the case may be, filed with the Commission prior to the date hereof, (y) a more recent public announcement by the Company or (z) any other notice by the Company or its transfer agent setting forth the number of shares of Common Stock outstanding. Upon the written request of the Holder, the Company shall within three (3) Trading Days confirm in writing or by electronic mail to the Holder the number of shares of Common Stock then outstanding. In any case, the number of outstanding shares of Common Stock shall be determined after giving effect to the conversion or exercise of securities of the Company, including this Warrant, by the Holder since the date as of which such number of outstanding shares of Common Stock was reported. By written notice to the Company, the Holder may from time to time increase or decrease the Maximum Percentage to any other percentage, not in excess of 19.99%, specified in such notice; provided that any such increase will not be effective until the sixty-first (61st) day after such notice is delivered to the Company. For purposes of this Section 11(a), the aggregate number of shares of Common Stock or voting securities beneficially owned by the Holder and its Affiliates and any other Persons whose beneficial ownership of Common Stock would be aggregated with the Holder’s for purposes of Section 13(d) of the Exchange Act shall include the shares of Common Stock issuable upon the exercise of this Warrant with respect to which such determination is being made, but shall exclude the number of shares of Common Stock which would be issuable upon (x) exercise of the remaining unexercised and non-cancelled portion of this Warrant by the Holder and (y) exercise or conversion of the unexercised, non-converted or non-cancelled portion of any other securities of the Company that do not have voting power (including without limitation any securities of the Company which would entitle the holder thereof to acquire at any time Common Stock, including without limitation any debt, preferred stock, right, option, warrant or other instrument that is at any time convertible into or exercisable or exchangeable for, or otherwise entitles the holder thereof to receive, Common Stock), is subject to a limitation on conversion or exercise analogous to the limitation contained herein and is beneficially owned by the Holder or any of its Affiliates and other Persons whose beneficial ownership of Common Stock would be aggregated with the Holder’s for purposes of Section 13(d) of the Exchange Act.

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(b) This Section 11 shall not restrict the number of shares of Common Stock which a Holder may receive or beneficially own in order to determine the amount of securities or other consideration that such Holder may receive in the event of a Fundamental Transaction as contemplated in Section 9(c) of this Warrant.

12. No Fractional Shares. No fractional Warrant Shares will be issued in connection with any exercise of this Warrant. In lieu of any fractional shares that would otherwise be issuable, the number of Warrant Shares to be issued shall be rounded down to the next whole number.

13. Notices. Any and all notices or other communications or deliveries hereunder (including, without limitation, any Exercise Notice) shall be in writing and shall be deemed given and effective on the earliest of (i) the date of transmission, if such notice or communication is delivered via facsimile or confirmed e-mail prior to 5:30 P.M., New York City time, on a Trading Day, (ii) the next Trading Day after the date of transmission, if such notice or communication is delivered via facsimile or confirmed e-mail on a day that is not a Trading Day or later than 5:30 P.M., New York City time, on any Trading Day, (iii) the Trading Day following the date of mailing, if sent by nationally recognized overnight courier service specifying next business day delivery, or (iv) upon actual receipt by the Person to whom such notice is required to be given, if by hand delivery. The addresses, facsimile numbers and e-mail addresses for such communications shall be:

If to the Company:

Aeglea BioTherapeutics, Inc.

Attention: Chief Financial Officer

805 Las Cimas Parkway

Suite 100, Austin, TX 78746

Telephone: (512) 394- 4188

Fax: (512) 872-5121

Email: cyork@aegleabio.com

If to the Holder, to its address, facsimile number or e-mail address set forth herein or on the books and records of the Company.

Or, in each of the above instances, to such other address, facsimile number or e-mail address as the recipient party has specified by written notice given to each other party at least five (5) days prior to the effectiveness of such change.

14. Warrant Agent. The Company shall initially serve as warrant agent under this Warrant. Upon ten (10) days’ notice to the Holder, the Company may appoint a new warrant agent. Any corporation into which the Company or any new warrant agent may be merged or any corporation resulting from any consolidation to which the Company or any new warrant agent shall be a party or any corporation to which the Company or any new warrant agent transfers substantially all of its corporate trust or shareholders services business shall be a successor warrant agent under this Warrant without any further act. Any such successor warrant agent shall promptly cause notice of its succession as warrant agent to be mailed (by first class mail, postage prepaid) to the Holder at the Holder’s last address as shown on the Warrant Register.

15. Miscellaneous.

(a) No Rights as a Stockholder. The Holder, solely in such Person’s capacity as a holder of this Warrant, shall not be entitled to vote or receive dividends or be deemed the holder of share capital of the Company for any purpose, nor shall anything contained in this Warrant be construed to confer upon the Holder, solely in such Person’s capacity as the Holder of this Warrant, any of the rights of a stockholder of the Company or any right to vote, give or withhold consent to any corporate action (whether any reorganization, issue of stock, reclassification of stock, consolidation, merger, amalgamation, conveyance or otherwise), receive notice of meetings, receive dividends or subscription rights, or otherwise, prior to the issuance to the Holder of the Warrant Shares which such Person is then entitled to receive upon the due exercise of this Warrant. In addition, nothing contained in this Warrant shall be construed as imposing any liabilities on the Holder to purchase any securities (upon exercise of this Warrant or otherwise) or as a stockholder of the Company, whether such liabilities are asserted by the Company or by creditors of the Company.

(b) Authorized Shares. Except and to the extent as waived or consented to by the Holder, the Company shall not by any action, including, without limitation, amending its certificate or articles of incorporation or through any reorganization, transfer of assets, consolidation, merger, dissolution, issue or sale of securities or any other voluntary action, avoid or seek to avoid the observance or performance of any of the terms of this Warrant, but will at all times in good faith assist in the carrying out of all such terms and in the taking of all such actions as may be necessary or appropriate to protect the rights of Holder as set forth in this Warrant against impairment. Without limiting the generality of the foregoing, the Company will (a) not increase the par value of any Warrant Shares above the amount payable therefor upon such exercise immediately prior to such increase in par value, (b) take all such action as may be necessary or appropriate in order that the Company may validly and legally issue fully paid and non-assessable Warrant Shares 

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upon the exercise of this Warrant, and (c) use commercially reasonable efforts to obtain all such authorizations, exemptions or consents from any public regulatory body having jurisdiction thereof as may be necessary to enable the Company to perform its obligations under this Warrant.

 

 (c) Successors and Assigns. Subject to compliance with applicable securities laws, this Warrant may be assigned by the Holder. This Warrant may not be assigned by the Company without the written consent of the Holder, except to a successor in the event of a Fundamental Transaction. This Warrant shall be binding on and inure to the benefit of the Company and the Holder and their respective successors and assigns. Subject to the preceding sentence, nothing in this Warrant shall be construed to give to any Person other than the Company and the Holder any legal or equitable right, remedy or cause of action under this Warrant. This Warrant may be amended only in writing signed by the Company and the Holder, or their successors and assigns.

(d) Amendment and Waiver. Except as otherwise provided herein, the provisions of the Warrants may be amended and the Company may take any action herein prohibited, or omit to perform any act herein required to be performed by it, only if the Company has obtained the written consent of the Holder.

(e) Acceptance. Receipt of this Warrant by the Holder shall constitute acceptance of and agreement to all of the terms and conditions contained herein.

(f) Governing Law; Jurisdiction. ALL QUESTIONS CONCERNING THE CONSTRUCTION, VALIDITY, ENFORCEMENT AND INTERPRETATION OF THIS WARRANT SHALL BE GOVERNED BY AND CONSTRUED AND ENFORCED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK WITHOUT REGARD TO THE PRINCIPLES OF CONFLICTS OF LAW THEREOF. EACH OF THE COMPANY AND THE HOLDER HEREBY IRREVOCABLY SUBMITS TO THE EXCLUSIVE JURISDICTION OF THE STATE AND FEDERAL COURTS SITTING IN THE CITY OF NEW YORK, BOROUGH OF MANHATTAN, FOR THE ADJUDICATION OF ANY DISPUTE HEREUNDER OR IN CONNECTION HEREWITH OR WITH ANY TRANSACTION CONTEMPLATED HEREBY OR DISCUSSED HEREIN (INCLUDING WITH RESPECT TO THE ENFORCEMENT OF ANY OF THE TRANSACTION DOCUMENTS), AND HEREBY IRREVOCABLY WAIVES, AND AGREES NOT TO ASSERT IN ANY SUIT, ACTION OR PROCEEDING, ANY CLAIM THAT IT IS NOT PERSONALLY SUBJECT TO THE JURISDICTION OF ANY SUCH COURT. EACH OF THE COMPANY AND THE HOLDER HEREBY IRREVOCABLY WAIVES PERSONAL SERVICE OF PROCESS AND CONSENTS TO PROCESS BEING SERVED IN ANY SUCH SUIT, ACTION OR PROCEEDING BY MAILING A COPY THEREOF VIA REGISTERED OR CERTIFIED MAIL OR OVERNIGHT DELIVERY (WITH EVIDENCE OF DELIVERY) TO SUCH PERSON AT THE ADDRESS IN EFFECT FOR NOTICES TO IT AND AGREES THAT SUCH SERVICE SHALL CONSTITUTE GOOD AND SUFFICIENT SERVICE OF PROCESS AND NOTICE THEREOF. NOTHING CONTAINED HEREIN SHALL BE DEEMED TO LIMIT IN ANY WAY ANY RIGHT TO SERVE PROCESS IN ANY MANNER PERMITTED BY LAW. EACH OF THE COMPANY AND THE HOLDER HEREBY WAIVES ALL RIGHTS TO A TRIAL BY JURY.

(g) Headings. The headings herein are for convenience only, do not constitute a part of this Warrant and shall not be deemed to limit or affect any of the provisions hereof.

(h) Severability. In case any one or more of the provisions of this Warrant shall be invalid or unenforceable in any respect, the validity and enforceability of the remaining terms and provisions of this Warrant shall not in any way be affected or impaired thereby, and the Company and the Holder will attempt in good faith to agree upon a valid and enforceable provision which shall be a commercially reasonable substitute therefor, and upon so agreeing, shall incorporate such substitute provision in this Warrant.

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]

 

 

7

 

Exhibit 4.1

IN WITNESS WHEREOF, the Company has caused this Warrant to be duly executed by its authorized officer as of the date first indicated above.

 

	
 
	
 
	
 

	
AEGLEA BIOTHERAPEUTICS, INC.

 

	
 
	
 
	
 

	
 
	
 

	
By: 
	
 
	
 

	
 
	
 
	
Name:

	
 
	
 
	
Title:

 

 

 

Exhibit 4.1

SCHEDULE 1

FORM OF EXERCISE NOTICE

[To be executed by the Holder to purchase shares of Common Stock under the Warrant]

Ladies and Gentlemen:

(1) The undersigned is the Holder of Warrant No.      (the “Warrant”) issued by Aeglea BioTherapeutics, Inc., a Delaware corporation (the “Company”). Capitalized terms used herein and not otherwise defined herein have the respective meanings set forth in the Warrant.

(2) The undersigned hereby exercises its right to purchase ___________Warrant Shares pursuant to the Warrant.

(3) The Holder intends that payment of the Exercise Price shall be made as (check one):

 

	
 
	
☐
	
Cash Exercise

 

	
 
	
☐
	
“Cashless Exercise” under Section 10 of the Warrant

(4) If the Holder has elected a Cash Exercise, the Holder shall pay the sum of $____________ in immediately available funds to the Company in accordance with the terms of the Warrant.

(5) Pursuant to this Exercise Notice, the Company shall deliver to the Holder Warrant Shares determined in accordance with the terms of the Warrant. The Warrant Shares shall be delivered to the following DWAC Account Number:

 

                                                                 

(6) By its delivery of this Exercise Notice, the undersigned represents and warrants to the Company that in giving effect to the exercise evidenced hereby the Holder will not beneficially own in excess of the number of shares of Common Stock (as determined in accordance with Section 13(d) of the Securities Exchange Act of 1934, as amended) permitted to be owned under Section 11(a) of the Warrant to which this notice relates.

 

	
 
	
 
	
 
	
 
	
 
	
 
	
 

	
Dated:
	
 
	
 
	
 
	
 
	
 
	
 

	
 
	
 
	
 
	
 

	
Name of Holder:  
	
 
	
 
	
 
	
 
	
 
	
 

	
 
	
 
	
 
	
 

	
By:
	
 
	
 
	
 
	
 
	
 
	
 

	
 
	
 
	
 
	
 

	
Name:
	
 
	
 
	
 
	
 
	
 
	
 

	
 
	
 
	
 
	
 

	
Title:
	
 
	
 
	
 
	
 
	
 
	
 

(Signature must conform in all respects to name of Holder as specified on the face of the Warrant)cepu_ex418

Exhibit 4.18

English
translation of the Brigadier López Power Plant transfer
contract

 

 

TRANSFER CONTRACT

 

 

This
Agreement of Purchase of the Goodwill and Execution of Closure
Works of the Combined Cycle of the Brigadier López Power Plant
-Central Termoeléctrica Brigadier López- (hereinafter,
the “Agreement”) is entered into in the City of Buenos
Aires, Argentine Republic, on June 14, 2019 by and between
INTEGRACIÓN ENERGÉTICA
ARGENTINA S.A., with offices at Av. del Libertador no. 1068,
2nd floor, City of Buenos Aires –represented in this act by
[] in his capacity as [] as per []– (hereinafter,
“IEASA”) and CENTRAL
PUERTO S.A., with offices at Tomás A. Edison 2701, City
of Buenos Aires –represented in this act by José Manuel
PAZOS and Leonardo MARINARO, in their capacity as attorneys-in-fact
as per the Broad Power-of-Attorney of Administration and
Disposition dated June 1, 2015, notarial record no.
465– (hereinafter, the “Transferee”; and together
with IEASA, the “Parties”; each of them individually,
the “Party”) under the following terms and
conditions:

 

 

BACKGROUND:

 

 

i.

IEASA made an
invitation for bids under Licitación Pública Nacional e
Internacional N. ° CTBL 01/2018 [National and
International Open Bid No. CTBL 01/2018] for the sale of Brigadier
López Power Plant -Central Térmica Brigadier López
or “CTBL”– in accordance with the regulations on
goodwill transference and execution of combined cycle closure works
(hereinafter, the “Bid”).

 

 

ii.

The Transferee made
a bid following the Terms and Conditions (hereinafter, “Terms
and Conditions”), which bid was considered as the most
convenient by IEASA and therefore, awarded.

 

 

iii.

The publications on
the transference of goodwill established in Section 2 of
Law no. 11867 (hereinafter, the “LTFC”) were made
between March 25 and 29, 2019 in the Official Gazette of the
Argentine Republic, in the newspaper El Litoral, and in the Official Gazette
of the province of Santa Fe between May 8 and 14,
2019.

 

 

iv.

Pursuant to Section
4 of the LTFC, on March 29, 2019, the following objections were
raised:

 

 

a.

Objection raised by
PONCE CONSTRUCCIONES SRL;

 

 

b.

Objection raised by
ROGOLEX S.A.;

 

 

c.

Objection raised by
DOMINGO IANNOZZI.

 

 

v.

All non-defined
terms in capital letters have the meaning assigned in the Terms and
Conditions.

 

 

1

 

 

THEREFORE, THE PARTIES AGREE ON THE FOLLOWING:

 

 

ARTICLE 1. EFFECTIVE DATE

 

 

1.1 The
Parties state that, without prejudice to this Agreement being
executed on this date (hereinafter, the “Goodwill Purchase
Agreement Date”), the legal, economic, financial, tax,
technical and/or any other effect that may arise as from the
execution of this Goodwill Purchase Agreement shall be considered
fulfilled as from 00:00 of April 1, 2019 in accordance with
the provisions and the scope established by the Terms and
Conditions and the Information Letter no. 11 as described
below.

 

 

1.1.1
The Parties agree that the credits regarding CTBL derived from the
transaction with MEM under the Turbogas Supply Agreement that
accrue after April 1, 2019 shall correspond to the Transferee, and
that the credits derived from the transactions with MEM regarding
CTBL that accrued before April 1, 2019 shall correspond to
IEASA.

 

 

1.1.2.
The expenditures that IEASA did in its ordinary course of business
on operations or facts in the period between April 1, 2019 and the
Goodwill Purchase Agreement Date, in accordance with the provisions
of the Terms and Conditions and its Information Letters, as well as
the payment of Debt Services under the Financial Trust shall be
reimbursed to IEASA by the Transferee.

 

 

As a
consequence of 1.1.1 and 1.1.2, the Party that received and/or
receives a payment that would correspond to the other Party shall
transfer such funds to the other Party within 5 (five) calendar
days, without any type of deductions.

 

 

1.1.3
Notwithstanding the foregoing, the Parties state and guarantee that
all statements, warranties and commitments that IEASA made in its
Terms and Conditions and its Information Letters and that the
Transferee made in its Bid and its Transference Commitment are true
and correct, both for April 1, 2019 and this date.

 

 

1.2 The
Parties herein put on record that, in compliance with Section 4 and
5 of LTFC and the objections raised in (iv) above, the intervening
Civil-law Notary, Civil-law notary Mariano Guyot (holder of
Register no. 2174 of the City of Buenos Aires, domiciled at Juncal
802, 5 K, of the City of Buenos Aires) makes the following
withholdings of the Minimum Amount in Cash, which amounts are
hereby transferred by the Transferee to the special account in
pesos of Banco Nación Argentina opened to these effects by the
Civil-law Notary. The account data is the following: Account
no. 0000369335, CBU (Universal Banking Code)
0110599520000003693353, Banco de la Nación Argentina, Branch
0085 Plaza de Mayo (“TFC Account”): (a) regarding the
objection raised by Rogolex S.A., he withholds an amount equivalent
in pesos of USD 1,180,100 and $700,000, which equals the
amount claimed by such company; (b) regarding the objection raised
by Ponce Construcciones S.A., he withholds $157,449,856.99, which
amount corresponds to the amount claimed in such objection; and (c)
regarding the objection raised by Domingo Iannozzi, there is not
withholding as no amount was claimed. As the account to which the
withheld amounts are transferred is in Argentine Pesos, the Parties
agree that the amounts in US dollars mentioned above are converted
into Argentine Pesos at the seller exchange rate of Banco de la
Nación Argentina for the closing of the day previous to the
Goodwill Purchase Agreement Date.

 

 

ARTICLE 2. TRANSFERENCE OF GOODWIL

 

 

IEASA
hereby grants and transfers to the Transferee –who hereby
acquires– the Goodwill and all assets, rights and obligations
forming it.

 

 

2

 

 

The
Parties put on record the following circumstances:

 

 

i.

The Transferee
hereby pays the amount of USD 152,172,500 in concept of Minimum
Amount in Cash and assigns LVFVD (sale settlements with due date to
be defined), which include interest and VAT and that, net of
applicable withholdings and converted into US dollars at the
exchange rate established in the Terms and Conditions represent USD
10,100,000, equivalent to the total Variable Amount. The mentioned
amount that is paid in concept of Minimum Amount in Cash does not
include the price of the Real Property transferred to the
Transferee through deed executed simultaneously to this
document.

 

 

The
Minimum Amount in Cash is hereby paid through bank transference to
the account in US dollars of IEASA no. 3334570-601/6, CBU
(Universal Banking Code) 2590050911333457060164, BANCO ITAU, hereby
deducting the amount equivalent in pesos of USD 1,180,100 and the
amounts in pesos of $700,000 and $157,449,856.99 that the Civil-law
Notary Mariano Guyot withholds and transfers to the TFC Account as
per Clause 1.2.

 

 

Once
the mentioned amount is withheld and the deposit is made on the
corresponding TFC Account –which is notified by Civil-law
Notary Mariano Guyot to the creditors that raised objections and
without them proving the attachment– and the term established
in Section 5 of Law no. 11867 elapses, the total amounts not
attached in favor of the opposing creditor shall be transferred by
the Civil-law Notary to IEASA on the working day following the due
date established in the aforementioned Section 5 to the account in
dollars mentioned in the previous paragraph using the translation
of pesos to dollars at the seller exchange rate of Banco de la
Nación Argentina corresponding to the closing of the day
previous to the effective transference date.

 

 

IEASA
hereby grants the corresponding receipt and payment receipt for the
total Minimum Amount in Cash, including the amount of withholdings
made in compliance with LTFC.

 

 

The
Variable Amount is hereby paid through the assignment of Offered
LVFVD documented through the Offered LVFVD Transference Agreement;
therefore, IEASA hereby grants the corresponding settlement receipt
and total payment receipt.

 

 

Moreover, the
Transferee hereby pays to IEASA the amount of USD 15,275,905
corresponding to VAT through bank transference in the terms of
Articles 32.1 (c) and 16.9 of the Terms and Conditions, being
this document sufficient receipt and payment receipt.

 

 

The
Parties put on record that the Transferee shall not contribute or
cause the contribution of additional funds to the aforementioned
for the acquisition –on its own behalf or through third
parties– of Debt Securities, which shall be fully redeemed by
IEASA, without extinguishing them, at its own cost in accordance
with the Terms and Conditions as amended by Information
Letters.

 

 

ii.

The Transferee
states that today it receives from IEASA the possession of the Real
Property over which IEASA has ownership and right of use. Moreover,
the Transferee receives from IEASA the Personal Property in
accordance with the Terms and Conditions.

 

 

iii.

As from the Date of
the Transference Agreement, the Transferee acquired all the rights
and obligations emerging from the Assumed Agreements detailed in
Exhibit II.

 

 

iv.

The Transferee
takes on all Employment Contracts as per Section 225 of the
Argentine Contract of Employment Act.

 

 

 

3

 

 

v.

The Transferee
takes on the Financial Debt in full, without conditions and
exclusively assuming the capacity of Trustor under the Financial
Trust Agreement. IEASA states and ensures that the
“Completion of the ENARSA-Brigadier López Project”
is done (as such terms are defined in the Trust
Agreement).

 

 

vi.

Simultaneously, the
Real Property’s deeds are hereby granted in favor of the
Transferee, which include the assignment of the right of use of the
land plot over which IEASA has the right to use.

 

 

vii.

The Transferee
hereby receives the Bid Bond, in full compliance.

 

 

viii.

According to
article 3.6 of the Terms and Conditions, all the documentation
incorporated to the Data Room is on a CD enclosed to this Goodwill
Purchase Agreement. All other original documentation associated to
the Goodwill shall be provided by IEASA in the term of five (5)
working days.

 

 

SECTION 3. GENERAL PROVISIONS

 

3.1.
IEASA is committed to collaborate with the Transferee in the
integration of the Goodwill to its own operations and systems,
within a context of maximum collaboration and contractual good
faith, ensuring that the transition is made in the shortest term
possible. In this context, IEASA shall provide the Transferee with
all the accounting or operational information related to the
Goodwill that the Transferee could reasonably need and request when
managing the operations of the Goodwill. If necessary, the Parties
shall agree on the hiring of all or any of the modules of the
service of administrative assistance of IEASA pursuant to section
33.2 of the Terms and Conditions, subject to the economic
conditions to agree on.

 

3.2. In
addition, the Parties agree to jointly conduct a gathering of
information and an inventory of the materials, equipment and
personal property within the term of thirty (30) days as from the
execution of this Agreement. The category of materials, equipment
and personal property shall include those indicated in the Data
Room and those in the lands and warehouses of IEASA.

 

3.3.
The Personal Property transferred includes the total personal
property and/or rights, tools, installations and other belongings
related to the exploitation of CTBL, which include the equipment,
machines, furniture, fixed fire extinguishing installations, tools,
supplies, spare parts (along with any additions or replacements
that took place, in accordance with the ordinary course of
business, until the date of this document), which are expressly
listed in Exhibit X of the Terms and Conditions, in the state that
they may be, with the normal wear and tear proper of their use in
the Goodwill, permanently located at CTBL.

 

3.4.
The provisions of the Terms and Conditions, including the
Information Letters, shall govern in case of any absence in this
Agreement.

 

3.5 Any
notice, whether judicial or otherwise, served by the Parties in
connection with this Agreement shall be sent to the following
domiciles, unless the Parties modify such domicile, in which case
the other Party must be duly notified within at least five (5)
previous days:

 

IEASA:
Av. del Libertador No. 1068, 2nd floor, City of Buenos
Aires.

 

Transferee:
Avenida Tomás A. Edison 2071, City of Buenos
Aires.

 

3.6.
This Agreement shall only be amended or modified by a written
agreement between the Parties.

 

3.7.
Any noncompliance or delay in the compliance by any of the Parties
of any right, power or privilege under this Agreement shall not be
considered a waiver thereof, nor shall the partial compliance of
any right, power or privilege prevent any other exercise thereof or
any other right, power or privilege under this Agreement. No waiver
shall be considered effective if it is not stated in writing by the
waiving Party.

 

3.8. No
Party shall be entitled to assign or transfer any or part of their
rights, obligations or responsibilities under this Agreement
without the previous written consent by the other
Party.

 

3.9.
The Stamp Tax for this Agreement shall be borne by the
Transferee.

 

In
witness whereof, the Parties sign two (2) copies of this Agreement,
stating the same contents and to only one effect, at the place and
on the date indicated in the heading herein.

 

 

4

Exhibit 4.18

English
translation of the Brigadier López Power Plant transfer
contract

 

 

 

Exhibit I

 

(i) A
CD with all the documentation incorporated to the Data
Room.

 

(ii)
The transference deed of Real Property on July 2,
2018.

 

(iii)
All documentation related to Registered Personal Property (this
documentation shall be provided in the term of 5 (five) working
days as from the execution of this Agreement).

 

 

5

Exhibit 4.18

English
translation of the Brigadier López Power Plant transfer
contract

 

 

 

Exhibit II

 

	

Contracting Party

	

Agreement

	

Domicile

	

Siemens
S.A.

	

Maintenance
Agreement drawn up by an Irrevocable Bid for the provision of long
term services (Bid no. SADG30311): made by SIEMENS S.A. on March
11, 2013 and accepted by IEASA on March 14, 2013 by Note IEASA no.
P5289/2013

	

Lavalle
1477, 4th
floor, City of Buenos Aires

	

Siemens
Energy Inc.

	

Parts
Sale Agreement drawn up by a Long Term Irrevocable Bid for the Sale
of Program Parts and Other Accessories and Services Abroad (Bid no.
EGA110313): made by Siemens on March 11, 2013 and accepted by IEASA
on March 14, 2013 by Note IEASA no. P5288/2013

	

4400
Alafaya Trail, Orlando, Florida

	

CAMMESA

	

Turbogas
Supply Agreement (electric energy supply and power available
agreement entered into by and between IEASA and CAMMESA on March
26, 2009 and their addendums)

	

Eduardo
Madero 942, City of Buenos Aires

	

CAMMESA

	

Turbosteam
Supply Agreement (electric energy supply and power available
agreement entered into by and between IEASA and CAMMESA on March
26, 2011)

	

Eduardo
Madero 942, City of Buenos Aires

	

Asociación
Civil Parque Industrial Sauce Viejo – Santa Fe
Province

	

Conciliation
Agreement between Santa Fe Province, Parque Industrial and IEASA on
July 3, 2018

	

Ruta
Nacional no.11, Km 457, Sauce Viejo, Santa Fe Province

	

Sauvimax
S.A.

	

Lease
Agreement drawn up by an Irrevocable Bid Lease of Real Property
located in Parque Industrial Sauce Viejo, Santa Fe Province on
September 10, 2018

	

Juan de
Garay 3466, City of Santa Fe, Santa Fe Province

	

Nación
Seguros S.A.

	

Policy
no. 419128

	

San
Martín 913, City of Buenos Aires

	

AON
Seguros

	

Emma de
la Barra 353, Dike 4, Puerto Madero, City of Buenos
Aires

	

Mercolab
S.A.

	

PO no.
4500014719 – Bromathological analysis of Food

	

Obispo
Gelabert 2656/8, Santa Fe

	

R.
Reitmann y Cia. S.A.

	

PO no.
47000000260 – commercial credit for fuels

	

Av. del
Trabajo 3016, Santo Tomé

	

Transporte
Contini S.R.L.

	

PO no.
4500015035 – extension for a month of PO no. 4500014354 for
personnel transportation services

	

Av.
Richieri 1544, Santo Tomé

	

Giovagnoli
S.R.L.

	

PO no.
4700000123 commercial credit for 12 months for the repair of low
voltage motors

	

Bv.
Oroño 2935, Rosario

	

Electromec
Inc. S.A.

	

PO no.
4700000124 - commercial credit for 12 months for the repair of
medium voltage motors

	

Colectora
1651, Villa Gobernador Galvez

	

Asven
S.R.L

	

PO no.
4700000215 – commercial credit for the repair and changing of
spare parts of the grundfos pump

	

Juan
Jose Paso 7410, Rosario

	

Scuaglia
Germán Andrés

	

PO no.
450014842 – Water hyacinth removal services

	

Margaritas
4607, Sauce Viejo, Santa Fe

	

Leonardo
Vergani

	

PO no.
4700000224 – coupling machining services

	

Facundo
Zuviria 5675, Santa Fe

	

Fernandez
Druetta Ezequiel Martín

	

PO no.
4500015036 – general tasks services

	

Lote
– Parque Industrial 116, Sauce Viejo, Santa Fe

	

Catering
gourmet S.R.L

	

PO no.
4500014557- Food service for the personnel

 

	

Av.
Presidente Perón 3985, Santa Fe

	

PO no.
4500017827 – provision and supply of food
service

 

 

 

6

 

 

	

Sanitek
SH

	

PO no.
45000013733 – plague control and eradication
service

	

San
Luis 3400, Santa Fe

	

Albosa
S.R.L.

	

PO no.
4500015013 – equity security service

	

Castillo
1333, City of Buenos Aires

	

Arginbureau
S.R.L.

	

PO no.
4500013741 – trimestral control of lifting equipment
service

	

Patallo
2206, El Palomar

	

Rivero
Julio Antonio

	

PO no.
4700000005 – draining of cavities

	

Pedro
Centeno 2264, Santa Fe

	

Favini
S.A.

	

PO no.
4700000189 – commercial credit for fuel for the fire
system

	

Av.
General Paz 7199, Santa Fe

	

Labac
S.A.

	

PO no.
4700000235 – monitoring of weather parameters

	

Calle
910, 2720, Colón

	

BLC
S.A.

	

PO no.
4500014757- technical support and maintenance service

	

27 de
Febrero 1195, Rosario, Santa Fe

	

Drager
Argentina S.A.

	

PO no.
4500014790- Calibration of gas detectors service

	

Colectora
Panamericana Este 1717, San Isidro

	

Aguas y
Procesos S.A.

	

PO no.
4700000288 Non-oxidant biocide

	

J.B.
Mitri, 2322, Sunchales

	

Rutero
Express

	

PO no.
4700000216- Load transportation service

	

Monteagudo
827, City of Buenos Aires

	

BICE
FIDEICOMISO S.A.; CAMMESA

	

Financial
Trust Agreement Enarsa – Brigadier Lopez

	

Av.
Belgrano 955, 12th floor, City of
Buenos Aires and Madero 1020, 1st floor, City of
Buenos Aires

 

 

 

 

 

 

7

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