Document:

EX-10.8

 Exhibit 10.8 
 INDEMNITY AGREEMENT 
 THIS INDEMNITY
AGREEMENT (this “Agreement”) dated as of                  ,         , is made by and
between REVANCE THERAPEUTICS, INC., a Delaware corporation (the “Company”), and
                     (“Indemnitee”). 
 RECITALS 
 A. The Company desires to attract and
retain the services of highly qualified individuals as directors, officers, employees and agents. 
 B. The
Company’s bylaws (the “Bylaws”) require that the Company indemnify its directors, and empowers the Company to indemnify its officers, employees and agents, as authorized by the Delaware General Corporation Law, as
amended (the “Code”), under which the Company is organized and such Bylaws expressly provide that the indemnification provided therein is not exclusive and contemplates that the Company may enter into separate agreements with
its directors, officers and other persons to set forth specific indemnification provisions. 
 C. Indemnitee does not
regard the protection currently provided by applicable law, the Company’s governing documents and available insurance as adequate under the present circumstances, and the Company has determined that Indemnitee and other directors, officers,
employees and agents of the Company may not be willing to serve or continue to serve in such capacities without additional protection. 
 D. The Company desires and has requested Indemnitee to serve or continue to serve as a director, officer, employee or agent of the Company, as the case may be, and has proffered this Agreement to
Indemnitee as an additional inducement to serve in such capacity. 
 E. Indemnitee is willing to serve, or to continue to
serve, as a director, officer, employee or agent of the Company, as the case may be, if Indemnitee is furnished the indemnity provided for herein by the Company. 
 AGREEMENT 
 NOW
THEREFORE, in consideration of the mutual covenants and agreements set forth herein, the parties hereto, intending to be legally bound, hereby agree as follows: 

1. Definitions. 
 (a) Agent. For purposes of this Agreement, the term “agent” of the Company means any person who: (i) is or was a director, officer, employee or other fiduciary of the Company
or a subsidiary of the Company; or (ii) is or was serving at the request or for the convenience of, or representing the interests of, the Company or a subsidiary of the Company, as a director, officer, employee or other fiduciary of a foreign
or domestic corporation, partnership, joint venture, trust or other enterprise. 
 (b) Expenses. For purposes of this
Agreement, the term “expenses” shall be broadly construed and shall include, without limitation, all direct and indirect costs of any type or nature whatsoever (including, without limitation, all attorneys’, witness, or other
professional fees and related disbursements, and other out-of-pocket costs of whatever nature), actually and reasonably incurred by 

  
 1. 

 
Indemnitee in connection with the investigation, defense or appeal of a proceeding or establishing or enforcing a right to indemnification under this Agreement, the Code or otherwise, and amounts
paid in settlement by or on behalf of Indemnitee, but shall not include any judgments, fines or penalties actually levied against Indemnitee for such individual’s violations of law. The term “expenses” shall also include reasonable
compensation for time spent by Indemnitee for which he is not compensated by the Company or any subsidiary or third party (i) for any period during which Indemnitee is not an agent, in the employment of, or providing services for compensation
to, the Company or any subsidiary; and (ii) if the rate of compensation and estimated time involved is approved by the directors of the Company who are not parties to any action with respect to which expenses are incurred, for Indemnitee while
an agent of, employed by, or providing services for compensation to, the Company or any subsidiary. 
 (c) Proceedings.
For purposes of this Agreement, the term “proceeding” shall be broadly construed and shall include, without limitation, any threatened, pending, or completed action, suit, arbitration, alternate dispute resolution mechanism, investigation,
inquiry, administrative hearing or any other actual, threatened or completed proceeding, whether brought in the right of the Company or otherwise and whether of a civil, criminal, administrative or investigative nature, and whether formal or
informal in any case, in which Indemnitee was, is or will be involved as a party or otherwise by reason of: (i) the fact that Indemnitee is or was a director or officer of the Company; (ii) the fact that any action taken by Indemnitee or
of any action on Indemnitee’s part while acting as director, officer, employee or agent of the Company; or (iii) the fact that Indemnitee is or was serving at the request of the Company as a director, officer, employee or agent of another
corporation, partnership, joint venture, trust, employee benefit plan or other enterprise, and in any such case described above, whether or not serving in any such capacity at the time any liability or expense is incurred for which indemnification,
reimbursement, or advancement of expenses may be provided under this Agreement. 
 (d) Subsidiary. For purposes of this
Agreement, the term “subsidiary” means any corporation or limited liability company of which more than 50% of the outstanding voting securities or equity interests are owned, directly or indirectly, by the Company and one or more of its
subsidiaries, and any other corporation, limited liability company, partnership, joint venture, trust, employee benefit plan or other enterprise of which Indemnitee is or was serving at the request of the Company as a director, officer, employee,
agent or fiduciary. 
 (e) Independent Counsel. For purposes of this Agreement, the term “independent counsel”
means a law firm, or a partner (or, if applicable, member) of such a law firm, that is experienced in matters of corporation law and neither presently is, nor in the past five (5) years has been, retained to represent: (i) the Company or
Indemnitee in any matter material to either such party, or (ii) any other party to the proceeding giving rise to a claim for indemnification hereunder. Notwithstanding the foregoing, the term “independent counsel” shall not include
any person who, under the applicable standards of professional conduct then prevailing, would have a conflict of interest in representing either the Company or Indemnitee in an action to determine Indemnitee’s rights under this Agreement.

 2. Agreement to Serve. Indemnitee will serve, or continue to serve, as a director, officer, employee or agent of the
Company or any subsidiary, as the case may be, faithfully and to the best of his or her ability, at the will of such corporation (or under separate agreement, if such agreement exists), in the capacity Indemnitee currently serves as an agent of such
corporation, so long as Indemnitee is duly appointed or elected and qualified in accordance with the applicable provisions of the bylaws or other applicable charter documents of such corporation, or until such time as Indemnitee tenders his or her
resignation in writing; provided, however, that nothing contained in this Agreement is intended as an employment agreement between Indemnitee and the Company or any of its subsidiaries or to create any right to continued employment of Indemnitee
with the Company or any of its subsidiaries in any capacity. 

  
 2. 

 The Company acknowledges that it has entered into this Agreement and assumes the obligations
imposed on it hereby, in addition to and separate from its obligations to Indemnitee under the Bylaws, to induce Indemnitee to serve, or continue to serve, as a director, officer, employee or agent of the Company, and the Company acknowledges that
Indemnitee is relying upon this Agreement in serving as a director, officer, employee or agent of the Company. 
 3.
Indemnification. 
 (a) Indemnification in Third Party Proceedings. Subject to Section 10 below, the Company
shall indemnify Indemnitee to the fullest extent permitted by the Code, as the same may be amended from time to time (but, only to the extent that such amendment permits Indemnitee to broader indemnification rights than the Code permitted prior to
adoption of such amendment), if Indemnitee is a party to or threatened to be made a party to or otherwise involved in any proceeding, for any and all expenses, actually and reasonably incurred by Indemnitee in connection with the investigation,
defense, settlement or appeal of such proceeding. 
 (b) Indemnification in Derivative Actions and Direct Actions by the
Company. Subject to Section 10 below, the Company shall indemnify Indemnitee to the fullest extent permitted by the Code, as the same may be amended from time to time (but, only to the extent that such amendment permits Indemnitee to
broader indemnification rights than the Code permitted prior to adoption of such amendment), if Indemnitee is a party to or threatened to be made a party to or otherwise involved in any proceeding by or in the right of the Company to procure a
judgment in its favor, against any and all expenses actually and reasonably incurred by Indemnitee in connection with the investigation, defense, settlement, or appeal of such proceedings. 

(c) Other Rights to Indemnification. Notwithstanding anything to the contrary set forth in this Agreement, the Company
hereby acknowledges that Indemnitees have or may have in the future certain rights to indemnification, advancement of expenses and/or insurance provided by other entities and/or organizations (collectively, the “Fund
Indemnitors”). The Company hereby agrees (i) that it is the indemnitor of first resort with respect to any threatened, pending or completed action, suit, proceeding or alternative dispute resolution mechanism, or any hearing,
inquiry or investigation that an Indemnitee believes might lead to the institution of any such action, suit, proceeding or alternative dispute resolution mechanism, whether civil, criminal, administrative, investigative or other which may give rise
to indemnification of an Indemnitee under the Indemnification Agreement (i.e., its obligations to each Indemnitee are primary and any obligation of the Fund Indemnitors to advance expenses or to provide indemnification for the same expenses or
liabilities incurred by Indemnitee are secondary); (ii) that it shall be required to advance the full amount of expenses incurred by an Indemnitee and shall be liable for the full amount of all expenses, judgments, penalties, fines and amounts
paid in settlement to the extent legally permitted and as required by the terms of the Indemnification Agreement and this Supplement and the Certificate of Incorporation or Bylaws of the Company (or any other agreement between the Company and such
Indemnitee), without regard to any rights an Indemnitee may have against the Fund Indemnitors, and, (iii) that it irrevocably waives, relinquishes and releases the Fund Indemnitors from any and all claims against the Fund Indemnitors for
contribution, subrogation or any other recovery of any kind in respect thereof. The Company further agrees that no advancement or payment by the Fund Indemnitors on behalf of an Indemnitee with respect to any claim for which an Indemnitee has sought
indemnification from the Company shall affect the foregoing and the Fund Indemnitors shall have a right of contribution and/or be subrogated to the extent of such advancement or payment to all of the rights of recovery of an Indemnitee against the
Company. The Company and each Indemnitee agree that the Fund Indemnitors are express third party beneficiaries of the terms of this Supplement. 

  
 3. 

 4. Indemnification of Expenses of Successful Party. Notwithstanding any other
provision of this Agreement, to the extent that Indemnitee has been successful on the merits or otherwise in defense of any proceeding or in defense of any claim, issue or matter therein, including the dismissal of any action without prejudice, the
Company shall indemnify Indemnitee against all expenses actually and reasonably incurred in connection with the investigation, defense or appeal of such proceeding. 
 5. Partial Indemnification. If Indemnitee is entitled under any provision of this Agreement to indemnification by the Company for some or a portion of any expenses actually and reasonably incurred
by Indemnitee in the investigation, defense, settlement or appeal of a proceeding, but is precluded by applicable law or the specific terms of this Agreement to indemnification for the total amount thereof, the Company shall nevertheless indemnify
Indemnitee for the portion thereof to which Indemnitee is entitled. 
 6. Advancement of Expenses. To the extent not
prohibited by law, the Company shall advance the expenses incurred by Indemnitee in connection with any proceeding, and such advancement shall be made within twenty (20) days after the receipt by the Company of a statement or statements
requesting such advances (which shall include invoices received by Indemnitee in connection with such expenses but, in the case of invoices in connection with legal services, any references to legal work performed or to expenditures made that would
cause Indemnitee to waive any privilege accorded by applicable law shall not be included with the invoice) and upon request of the Company, an undertaking to repay the advancement of expenses if and to the extent that it is ultimately determined by
a court of competent jurisdiction in a final judgment, not subject to appeal, that Indemnitee is not entitled to be indemnified by the Company. Advances shall be unsecured, interest free and without regard to Indemnitee’s ability to repay the
expenses. Advances shall include any and all expenses actually and reasonably incurred by Indemnitee pursuing an action to enforce Indemnitee’s right to indemnification under this Agreement, or otherwise and this right of advancement, including
expenses incurred preparing and forwarding statements to the Company to support the advances claimed. Indemnitee acknowledges that the execution and delivery of this Agreement shall constitute an undertaking providing that Indemnitee shall, to the
fullest extent required by law, repay the advance if and to the extent that it is ultimately determined by a court of competent jurisdiction in a final judgment, not subject to appeal, that Indemnitee is not entitled to be indemnified by the
Company. The right to advances under this Section shall continue until final disposition of any proceeding, including any appeal therein. This Section 6 shall not apply to any claim made by Indemnitee for which indemnity is excluded pursuant to
Section 10(b). 
 7. Notice and Other Indemnification Procedures. 

(a) Notification of Proceeding. Indemnitee will notify the Company in writing promptly upon being served with any summons,
citation, subpoena, complaint, indictment, information or other document relating to any proceeding or matter which may be subject to indemnification or advancement of expenses covered hereunder. The failure of Indemnitee to so notify the Company
shall not relieve the Company of any obligation which it may have to Indemnitee under this Agreement or otherwise. 
 (b)
Request for Indemnification and Indemnification Payments. Indemnitee shall notify the Company promptly in writing upon receiving notice of any demand, judgment or other requirement for payment that Indemnitee reasonably believes to be subject to
indemnification under the terms of this Agreement, and shall request payment thereof by the Company. Indemnification payments requested by Indemnitee under Section 3 hereof shall be made by the Company no later than sixty (60) days after
receipt of the written request of Indemnitee. Claims for advancement of expenses shall be made under the provisions of Section 6 herein. 

  
 4. 

 (c) Application for Enforcement. In the event the Company fails to make timely
payments as set forth in Sections 6 or 7(b) above, Indemnitee shall have the right to apply to any court of competent jurisdiction for the purpose of enforcing Indemnitee’s right to indemnification or advancement of expenses pursuant to this
Agreement. In such an enforcement hearing or proceeding, the burden of proof shall be on the Company to prove that indemnification or advancement of expenses to Indemnitee is not required under this Agreement or permitted by applicable law. Any
determination by the Company (including its Board of Directors, stockholders or independent counsel) that Indemnitee is not entitled to indemnification hereunder, shall not be a defense by the Company to the action nor create any presumption that
Indemnitee is not entitled to indemnification or advancement of expenses hereunder. 
 (d) Indemnification of Certain
Expenses. The Company shall indemnify Indemnitee against all expenses incurred in connection with any hearing or proceeding under this Section 7 unless the Company prevails in such hearing or proceeding on the merits in all material
respects. 
 8. Assumption of Defense. In the event the Company shall be requested by Indemnitee to pay the expenses of
any proceeding, the Company, if appropriate, shall be entitled to assume the defense of such proceeding, or to participate to the extent permissible in such proceeding, with counsel reasonably acceptable to Indemnitee. Upon assumption of the defense
by the Company and the retention of such counsel by the Company, the Company shall not be liable to Indemnitee under this Agreement for any fees of counsel subsequently incurred by Indemnitee with respect to the same proceeding, provided that
Indemnitee shall have the right to employ separate counsel in such proceeding at Indemnitee’s sole cost and expense. Notwithstanding the foregoing, if Indemnitee’s counsel delivers a written notice to the Company stating that such counsel
has reasonably concluded that there may be a conflict of interest between the Company and Indemnitee in the conduct of any such defense or the Company shall not, in fact, have employed counsel or otherwise actively pursued the defense of such
proceeding within a reasonable time, then in any such event the fees and expenses of Indemnitee’s counsel to defend such proceeding shall be subject to the indemnification and advancement of expenses provisions of this Agreement. 

9. Insurance. To the extent that the Company maintains an insurance policy or policies providing liability insurance for
directors, officers, employees, or agents of the Company or of any subsidiary (“D&O Insurance”), Indemnitee shall be covered by such policy or policies in accordance with its or their terms to the maximum extent of the
coverage available for any such director, officer, employee or agent under such policy or policies. If, at the time of the receipt of a notice of a claim pursuant to the terms hereof, the Company has D&O Insurance in effect, the Company shall
give prompt notice of the commencement of such proceeding to the insurers in accordance with the procedures set forth in the respective policies. The Company shall thereafter take all necessary or desirable action to cause such insurers to pay, on
behalf of Indemnitee, all amounts payable as a result of such proceeding in accordance with the terms of such policies. 

10. Exceptions. 
 (a) Certain Matters. Any provision herein to the contrary notwithstanding, the Company shall not be obligated pursuant to the terms of this Agreement to indemnify Indemnitee on account of any
proceeding with respect to (i) remuneration paid to Indemnitee if it is determined by final judgment or other final adjudication that such remuneration was in violation of law (and, in this respect, both the Company and Indemnitee have been
advised that the Securities and Exchange Commission believes that indemnification for liabilities arising under the federal securities laws is against public policy and is, therefore, unenforceable and that claims for indemnification should be
submitted to appropriate courts for adjudication, as indicated in Section 10(d) below); (ii) a final judgment rendered 

  
 5. 

 
against Indemnitee for an accounting, disgorgement or repayment of profits made from the purchase or sale by Indemnitee of securities of the Company against Indemnitee or in connection with a
settlement by or on behalf of Indemnitee to the extent it is acknowledged by Indemnitee and the Company that such amount paid in settlement resulted from Indemnitee’s conduct from which Indemnitee received monetary personal profit, pursuant to
the provisions of Section 16(b) of the Securities Exchange Act of 1934, as amended, or other provisions of any federal, state or local statute or rules and regulations thereunder; (iii) a final judgment or other final adjudication that
Indemnitee’s conduct was in bad faith, knowingly fraudulent or deliberately dishonest or constituted willful misconduct (but only to the extent of such specific determination); or (iv) on account of conduct that is established by a final
judgment as constituting a breach of Indemnitee’s duty of loyalty to the Company or resulting in any personal profit or advantage to which Indemnitee is not legally entitled. For purposes of the foregoing sentence, a final judgment or other
adjudication may be reached in either the underlying proceeding or action in connection with which indemnification is sought or a separate proceeding or action to establish rights and liabilities under this Agreement. 

(b) Claims Initiated by Indemnitee. Any provision herein to the contrary notwithstanding, the Company shall not be obligated to
indemnify or advance expenses to Indemnitee with respect to proceedings or claims initiated or brought by Indemnitee against the Company or its directors, officers, employees or other agents and not by way of defense, except (i) with respect to
proceedings brought to establish or enforce a right to indemnification under this Agreement or under any other agreement, provision in the Bylaws or Certificate of Incorporation or applicable law, or (ii) with respect to any other proceeding
initiated by Indemnitee that is either approved by the Board of Directors or Indemnitee’s participation is required by applicable law. However, indemnification or advancement of expenses may be provided by the Company in specific cases if the
Board of Directors determines it to be appropriate. 
 (c) Unauthorized Settlements. Any provision herein to the contrary
notwithstanding, the Company shall not be obligated pursuant to the terms of this Agreement to indemnify Indemnitee under this Agreement for any amounts paid in settlement of a proceeding effected without the Company’s written consent. Neither
the Company nor Indemnitee shall unreasonably withhold consent to any proposed settlement; provided, however, that the Company may in any event decline to consent to (or to otherwise admit or agree to any liability for indemnification hereunder in
respect of) any proposed settlement if the Company is also a party in such proceeding and determines in good faith that such settlement is not in the best interests of the Company and its stockholders. 

(d) Securities Act Liabilities. Any provision herein to the contrary notwithstanding, the Company shall not be obligated pursuant
to the terms of this Agreement to indemnify Indemnitee or otherwise act in violation of any undertaking appearing in and required by the rules and regulations promulgated under the Securities Act of 1933, as amended (the
“Act”), or in any registration statement filed with the SEC under the Act. Indemnitee acknowledges that paragraph (h) of Item 512 of Regulation S-K currently generally requires the Company to undertake in connection
with any registration statement filed under the Act to submit the issue of the enforceability of Indemnitee’s rights under this Agreement in connection with any liability under the Act on public policy grounds to a court of appropriate
jurisdiction and to be governed by any final adjudication of such issue. Indemnitee specifically agrees that any such undertaking shall supersede the provisions of this Agreement and to be bound by any such undertaking. 

11. Nonexclusivity and Survival of Rights. The provisions for indemnification and advancement of expenses set forth in this
Agreement shall not be deemed exclusive of any other rights which Indemnitee may at any time be entitled under any provision of applicable law, the Company’s Certificate of Incorporation, Bylaws or other agreements, both as to action in
Indemnitee’s official 

  
 6. 

 
capacity and Indemnitee’s action as an agent of the Company, in any court in which a proceeding is brought, and Indemnitee’s rights hereunder shall continue after Indemnitee has ceased
acting as an agent of the Company and shall inure to the benefit of the heirs, executors, administrators and assigns of Indemnitee. The obligations and duties of the Company to Indemnitee under this Agreement shall be binding on the Company and its
successors and assigns until terminated in accordance with its terms. The Company shall require any successor (whether direct or indirect, by purchase, merger, consolidation or otherwise) to all or substantially all of the business or assets of the
Company, expressly to assume and agree to perform this Agreement in the same manner and to the same extent that the Company would be required to perform if no such succession had taken place. 

No amendment, alteration or repeal of this Agreement or of any provision hereof shall limit or restrict any right of Indemnitee under
this Agreement in respect of any action taken or omitted by such Indemnitee in his or her corporate status prior to such amendment, alteration or repeal. To the extent that a change in the Code, whether by statute or judicial decision, permits
greater indemnification or advancement of expenses than would be afforded currently under the Company’s Certificate of Incorporation, Bylaws and this Agreement, it is the intent of the parties hereto that Indemnitee shall enjoy by this
Agreement the greater benefits so afforded by such change. No right or remedy herein conferred is intended to be exclusive of any other right or remedy, and every other right and remedy shall be cumulative and in addition to every other right and
remedy given hereunder or now or hereafter existing at law or in equity or otherwise. The assertion or employment of any right or remedy hereunder, or otherwise, by Indemnitee shall not prevent the concurrent assertion or employment of any other
right or remedy by Indemnitee. 
 12. Term. This Agreement shall continue until and terminate upon the later of:
(a) five (5) years after the date that Indemnitee shall have ceased to serve as a director or and/or officer, employee or agent of the Company; or (b) one (1) year after the final termination of any proceeding, including any
appeal then pending, in respect to which Indemnitee was granted rights of indemnification or advancement of expenses hereunder. 

No legal action shall be brought and no cause of action shall be asserted by or in the right of the Company against an Indemnitee or an
Indemnitee’s estate, spouse, heirs, executors or personal or legal representatives after the expiration of five (5) years from the date of accrual of such cause of action, and any claim or cause of action of the Company shall be
extinguished and deemed released unless asserted by the timely filing of a legal action within such five-year period; provided, however, that if any shorter period of limitations is otherwise applicable to such cause of action, such shorter period
shall govern. 
 13. Subrogation. In the event of payment under this Agreement, the Company shall be subrogated to the
extent of such payment to all of the rights of recovery of Indemnitee, who, at the request and expense of the Company, shall execute all papers required and shall do everything that may be reasonably necessary to secure such rights, including the
execution of such documents necessary to enable the Company effectively to bring suit to enforce such rights. 
 14.
Interpretation of Agreement. It is understood that the parties hereto intend this Agreement to be interpreted and enforced so as to provide indemnification to Indemnitee to the fullest extent now or hereafter permitted by law. 

15. Severability. If any provision of this Agreement shall be held to be invalid, illegal or unenforceable for any reason
whatsoever, (a) the validity, legality and enforceability of the remaining provisions of the Agreement (including without limitation, all portions of any paragraphs of this Agreement containing any such provision held to be invalid, illegal or
unenforceable, that are not themselves invalid, illegal or unenforceable) shall not in any way be affected or impaired thereby; and 

  
 7. 

 
(b) to the fullest extent possible, the provisions of this Agreement (including, without limitation, all portions of any paragraph of this Agreement containing any such provision held to be
invalid, illegal or unenforceable, that are not themselves invalid, illegal or unenforceable) shall be construed so as to give effect to the intent manifested by the provision held invalid, illegal or unenforceable and to give effect to
Section 14 hereof. 
 16. Amendment and Waiver. No supplement, modification, amendment, or cancellation of this
Agreement shall be binding unless executed in writing by the parties hereto. No waiver of any of the provisions of this Agreement shall be deemed or shall constitute a waiver of any other provision hereof (whether or not similar) nor shall such
waiver constitute a continuing waiver. 
 17. Notice. Except as otherwise provided herein, any notice or demand which, by
the provisions hereof, is required or which may be given to or served upon the parties hereto shall be in writing and, if by telegram, telecopy or telex, shall be deemed to have been validly served, given or delivered when sent, if by overnight
delivery, courier or personal delivery, shall be deemed to have been validly served, given or delivered upon actual delivery and, if mailed, shall be deemed to have been validly served, given or delivered three (3) business days after deposit
in the United States mail, as registered or certified mail, with proper postage prepaid and addressed to the party or parties to be notified at the addresses set forth on the signature page of this Agreement (or such other address(es) as a party may
designate for itself by like notice). If to the Company, notices and demands shall be delivered to the attention of the Secretary of the Company. 
 18. Governing Law. This Agreement shall be governed exclusively by and construed according to the laws of the State of Delaware, as applied to contracts between Delaware residents entered into and
to be performed entirely within Delaware. 
 19. Counterparts. This Agreement may be executed in one or more
counterparts, each of which shall for all purposes be deemed to be an original but all of which together shall constitute but one and the same Agreement. Only one such counterpart need be produced to evidence the existence of this Agreement.

 20. Headings. The headings of the sections of this Agreement are inserted for convenience only and shall not be deemed
to constitute part of this Agreement or to affect the construction hereof. 
 21. Entire Agreement. This Agreement
constitutes the entire agreement between the parties with respect to the subject matter hereof and supersedes all prior agreements, understandings and negotiations, written and oral, between the parties with respect to the subject matter of this
Agreement; provided, however, that this Agreement is a supplement to and in furtherance of the Company’s Certificate of Incorporation, Bylaws, the Code and any other applicable law, and shall not be deemed a substitute therefor, and does not
diminish or abrogate any rights of Indemnitee thereunder. 

  
 8. 

 IN WITNESS WHEREOF, the
parties hereto have entered into this Agreement effective as of the date first above written. 
  

					
	REVANCE THERAPEUTICS, INC.
		
	By:	 	  

		 	Name:	 	  

		 	Title:	 	  

 

					
	Address:	 	7555 Gateway Boulevard
		 	Newark, CA 94560
	
	INDEMNITEE
	
	  

	Signature of Indemnitee
	
	  

	Print or Type Name of Indemnitee
		
	Address:EX-10.9

 Exhibit 10.9 
 LEASE 
 by and between 

BMR-GATEWAY BOULEVARD LLC, 
 a Delaware limited liability company 
 and 

REVANCE THERAPEUTICS, INC., 
 a Delaware corporation 
 BMR Form Dated 2/5/08 

 LEASE 

THIS LEASE (this “Lease”) is entered into as of this 31st day of March, 2008 (the “Execution Date”), by and
between BMR-GATEWAY BOULEVARD LLC. a Delaware limited liability company (“Landlord”), and REVANCE THERAPEUTICS, INC., a Delaware corporation (“Tenant”). 

RECITALS 
 A. WHEREAS, Landlord owns certain real property (the “Property”) and the improvements thereon located at 7555 Gateway Boulevard in Newark, California, including the buildings located
thereon; 
 B. WHEREAS, concurrent with the execution of this Lease, Landlord and Tenant are entering into that certain Office
Lease dated as of the Execution Date (the “Office Lease”) for a portion of Building No. 2 (the “Building”). The term of the Office Lease shall terminate as of the Term Commencement Date under this Lease; and

 C. WHEREAS, Landlord wishes to lease to Tenant, and Tenant desires to lease from Landlord, Building No. 2 (the
“Building”) on the Property, pursuant to the terms and conditions of this Lease, as detailed below. 

AGREEMENT 
 NOW, THEREFORE, Landlord and Tenant, in consideration of the mutual promises contained herein and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged,
and intending to be legally bound, agree as follows: 
 1. Lease of Premises. Landlord hereby leases to Tenant, and Tenant hereby leases
from Landlord, the Premises, marked as “Phase 3” on Exhibit A attached hereto, for use by Tenant in accordance with the Permitted Use (as defined below) and no other uses. From the Execution Date until the Term Commencement
Date, the term “Premises,” as used in this Lease, shall mean the Building minus the premises leased pursuant to the Office Lease (such differential premises, the “Manufacturing Premises”). From and after the Term
Commencement Date, the term “Premises,” as used in this Lease, shall mean the Building. The Property and all landscaping, parking facilities and other improvements and appurtenances related thereto, including, without limitation,
the Premises and other buildings located on the Property, are hereinafter collectively referred to as the “Project.” All portions of the Project that are for the non-exclusive use of tenants of the Project, including, without
limitation, driveways; sidewalks; parking areas; landscaped areas; service corridors; stairways; elevators; public restrooms; public lobbies; and the amenities building (“Amenities Building”) in which Landlord may provide, among
other things, food services, a fitness center and a conference center (“Amenities Building Services”), are hereinafter referred to as “Common Area.” 
 2. Basic Lease Provisions. For convenience of the parties, certain basic provisions of this Lease are set forth herein. The provisions set forth herein are subject to the remaining terms and
conditions of this Lease and are to be interpreted in light of such remaining terms and conditions. 
 2.1. This Lease shall
take effect upon the date of execution and delivery hereof by all parties hereto and, except as specifically otherwise provided within this Lease, each of the provisions hereof shall be binding upon and inure to the benefit of Landlord and Tenant
from the date of execution and delivery hereof by all parties hereto. 

 2.2. In the definitions below, each current Rentable Area (as defined below) is expressed in
rentable square footage. Rentable Area and Tenant’s Pro Rata Share (as defined below) are all subject to adjustment as provided in this Lease. 
  

			
	 Definition or Provision
	  	Means the Following
(As of the Term
Commencement Date)
	 Rentable Area of Premises
	  	90,378 square feet
	 Rentable Area of Project
	  	1,389,517 square feet
	 Tenant’s Pro Rata Share of Building
	  	100.00%
	 Tenant’s Pro Rata Share of Project
	  	6.50%

 2.3. Initial monthly and annual installments of Base Rent for the Premises (“Base Rent”)
as of the Term Commencement Date (as defined below), subject to adjustment under this Lease: 
  

									
	 Months
	  	Per Rentable Square Foot	  	Square
Feet	 	  	Total
Monthly
	 1-12
	  	$2.25 monthly	  	 	50,000	  	  	$112,500.00
	 13-18
	  	$2.50 monthly	  	 	80,000	  	  	$200,000.00
	 19-24
	  	$2.90 monthly	  	 	90,378	  	  	$262,096.20
	 25-36
	  	$2.99 monthly	  	 	90,378	  	  	$270,230.22
	 37-144
	  	Increases in accordance with Article 9	  	 	90,378	  	  	(Varies)

 2.4. Estimated Term Commencement Date (as defined in Section 4.2 below): June 1, 2009

 2.5. Estimated Term Expiration Date: May 31, 2021 

2.6. Security Deposit: $810,000, subject to adjustment in accordance with the terms hereof 

2.7. Permitted Use: General office, laboratory, vivarium, research and manufacturing use in conformity with Applicable Laws (as defined
below) 
  

					
	2.8.	 	Address for Rent Payment:	  	 BMR-Gateway Boulevard LLC
 P.O.
Box 511231
 Los Angeles, California 90051-2997

			
	2.9.	 	Address for Notices to Landlord:	  	 BMR-Gateway Boulevard LLC

17190 Bernardo Center Drive
 San Diego,
California 92128
 Attn: General Counsel/Real Estate

			
	2.10.	 	Address for Notices to Tenant:	  	
			
		 	Prior to the Term Commencement Date:	  	 Revance Therapeutics Inc.
 2400
Bayshore Parkway, Suite 100
 Mountain View, California 94043
 Attention: L. Daniel Browne
 Facsimile: (650)
230-4501

  
 2 

					
			
		 	After the Term Commencement Date:	  	At the Premises
			
		 	 with a copy to:
	  	 Cooley Godward Kronish LLP
 101
California Street
 Fifth Floor
 San
Francisco, California 94111
 Attention: Anna Pope
 Facsimile: (415) 693-2222

 2.11. The following Exhibits are attached hereto and incorporated herein by reference: 

 

			
	Exhibit A	  	Premises
	Exhibit B	  	Work Letter
	Exhibit C	  	Acknowledgement of Term Commencement Date and Term Expiration Date
	Exhibit D	  	Form of Additional TI Costs Acceptance Letter
	Exhibit E	  	Form of Letter of Credit
	Exhibit F	  	Rules and Regulations
	Exhibit G	  	Hazardous Materials List
	Exhibit H	  	Tenant’s Personal Property
	Exhibit I	  	Form of Tenant Estoppel Certificate
	Exhibit J	  	Form of Landlord Estoppel Certificate
	Exhibit K	  	Reserved Parking
	Exhibit L	  	Location of Exterior Items
	Exhibit M	  	Subordinate ROFR Premises
	Exhibit N	  	Commissioning

 3. Term. The actual term of this Lease shall be one hundred forty-four (144) months (the
“Term”), starting on the actual Term Commencement Date (as defined in Section 4.2) and ending on the Term Expiration Date, subject to earlier termination of this Lease as provided herein. 

4. Possession and Commencement Date. 
 4.1. Prior to the Term Commencement Date, Tenant shall occupy a portion of the Premises consisting of approximately twenty-two thousand (22,000) square feet of office space (“Office
Space”) pursuant to the terms of the Office Lease. Tenant’s occupancy of the Office Space prior to the Term Commencement Date hereunder shall be subject to the terms and provisions of the Office Lease and shall not be subject to the
provisions of this Lease. Landlord shall tender possession of the Manufacturing Premises to Tenant on the Term Commencement Date, with the Tenant Improvement work required of Landlord described in the Work Letter attached hereto as Exhibit B
(the “Work Letter”) Substantially Complete (as defined below). Tenant agrees that in the event such work is not Substantially Complete on or before the Estimated Term Commencement Date for any reason, then (a) this Lease shall
not be void or voidable, (b) Landlord shall not be liable to Tenant for any loss or damage resulting therefrom, (c) the Term Expiration Date shall be extended accordingly, (d) Tenant shall not be responsible for the payment of any Rent (as
defined below) until the actual Term Commencement Date as described in Section 4.2 occurs and (e) Tenant shall continue to occupy the Office Space pursuant to the provisions of the Office Lease until the Term Commencement Date. The
term “Substantially Complete” or “Substantial Completion” means that (y) the Tenant Improvements have been substantially completed and commissioned in accordance with the Work Letter (except for minor punch
list items that do not materially and substantially interfere with Tenant’s ability to use the Premises for the Permitted Use (“Punchlist Items”)) in a good and workmanlike manner, in accordance with the Approved Plans (as
defined in Section 2.2(e)(i) of the Work Letter) and all Applicable Laws and (z) a temporary certificate of occupancy, or its equivalent, from the municipality in which the Property is located, has been delivered to Tenant.
Notwithstanding anything to the contrary contained herein, if Landlord has not delivered the Manufacturing Premises with the Tenant Improvements Substantially Completed to Tenant on or before February 28, 2010, as such date may be extended by
Tenant Delays and/or Force Majeure, Tenant shall have the right thereafter to terminate this Lease effective as of June 30, 2010, by 

  
 3 

 
giving written notice thereof to Landlord no later than February 28, 2010, and upon such termination and provided Tenant has not defaulted under its obligations under this Lease,
Landlord shall return any sums previously deposited by Tenant with Landlord and any prepaid rent paid by Tenant to Landlord (in each case to which Tenant is entitled under this Lease), and neither party shall have any further liability to the other,
except for those provisions that, by their terms, survive the expiration or earlier termination of this Lease. Notwithstanding anything in this Lease (including the Work Letter) to the contrary, Landlord’s obligation to timely achieve
Substantial Completion shall be subject to extension on a day-for-day basis as a result of Tenant Delay (as defined below); accident; breakage; repair; strike, lockout or other labor disturbance or labor dispute of any character; act of terrorism;
shortage of materials, which shortage is not unique to Landlord or Tenant, as the case may be; governmental regulation, moratorium or other governmental action, inaction or delay; or Landlord’s inability, despite the exercise of reasonable
diligence or by any other cause, including Landlord’s negligence, to furnish any such utility or service (collectively, “Force Majeure”). “Tenant Delay” shall mean a delay in the completion of the Tenant
Improvements that is caused by or results from a Tenant Event (as defined below); provided, however, that in no event shall Landlord be required to incur additional costs or take extraordinary measures to mitigate the cost or schedule effects
of a Tenant Event. Landlord shall endeavor to provide Tenant with prompt written notice of any act, failure to act or condition that Landlord contends could reasonably be expected to result in a Tenant Delay. “Tenant Event” means
(1) the failure of Tenant to timely deliver items in accordance with the Work Letter, (2) Tenant’s failure to fulfill its obligations as set forth in the Schedule (as defined in the Work Letter), (3) an act or failure to act of
Tenant or its agents, employees or contractors that interferes with the progress of the Tenant Improvements or (4) the failure of Tenant to timely approve or disapprove any plans or drawings within the respective time periods set forth in the
Work Letter. 
 4.2. The “Term Commencement Date” shall be the day Landlord tenders possession of the
Manufacturing Premises to Tenant with all work required of Landlord pursuant to the Work Letter Substantially Complete. Tenant shall execute and deliver to Landlord written acknowledgment of the actual Term Commencement Date and the Term Expiration
Date within ten (10) days after Tenant takes occupancy of the Manufacturing Premises, in the form attached as Exhibit C hereto. Failure to execute and deliver such acknowledgment, however, shall not affect the Term Commencement Date or
Landlord’s or Tenant’s liability hereunder. Notwithstanding anything to the contrary set forth in this Lease, Tenant shall not be responsible for the payment of any Base Rent or Tenant’s Pro Rata Share of Operating Expenses (as
defined below) until the actual Term Commencement Date occurs. In the event the satisfaction of the requirements for the Substantial Completion of the Tenant Improvements has been delayed by any Tenant Delay (any such period being referred to herein
as the “Tenant Delay Period”), then (a) Tenant shall be responsible for the payment of monthly installments of Base Rent accruing during the Tenant Delay Period, prorated for any partial month, within thirty (30) days after the
Term Commencement Date, and (b) the Term Expiration Date shall be accelerated by a period equal to the Tenant Delay Period. 
 4.3. Landlord shall permit Tenant to enter upon the Manufacturing Premises sixty (60) days prior to the Term Commencement Date for the purpose of installing IT infrastructure and furniture;
provided that Tenant furnish to Landlord evidence satisfactory to Landlord that liability insurance coverages required of Tenant under the provisions of Article 24 are in effect. Such entry shall be subject to all the terms and
conditions of this Lease, other than the payment of Base Rent and Tenant’s Pro Rata Share of Operating Expenses. 
 4.4.
Landlord shall cause to be constructed and commissioned in accordance with the Exhibit N attached hereto the tenant improvements in the Manufacturing Premises (the “Tenant Improvements”) pursuant to the Work Letter at a cost
to Landlord not to exceed (a) Thirteen Million One Hundred Four Thousand Eight Hundred Ten Dollars ($13,104,810) (based upon One Hundred Forty-Five Dollars ($145) per rentable square foot) (the “Base TI Costs”) plus (b) if
properly requested by Tenant pursuant to this Section 4.4, Six Million Seven Hundred Seventy-Eight Thousand Three Hundred Fifty Dollars ($6,778,350) (based upon Seventy-Five Dollars ($75) per rentable square foot) (the
“Additional TI Costs”), for a total of Nineteen Million Eight Hundred Eighty-Three Thousand One Hundred Sixty Dollars ($19,883,160) (based upon Two Hundred Twenty Dollars ($220) per rentable square foot). The Base TI Costs, together
with the Additional TI Costs (if properly authorized by Tenant pursuant to this Section 4.4), shall be referred to herein as the “TI Costs.” The TI Costs shall include the costs of (n) third party

  
 4 

 
construction management hired by Landlord, (o) construction, (p) space planning, architect, engineering and other related services performed by third parties unaffiliated with Tenant,
(q) building permits and other taxes, fees, charges and levies by Governmental Authorities (as defined below) for permits or for inspections of the Tenant Improvements, and (r) costs and expenses for labor, material, equipment and
fixtures. Upon execution of this Lease, Landlord shall reimburse Tenant for all architectural, engineering and other design and planning costs incurred or paid by Tenant in connection with the Tenant Improvements at the Project (but not at any other
properties), as part of the TI Costs. In no event shall TI Costs include (v) any payments made by Tenant or amounts otherwise payable to SRM Consulting Services, LLC (which amounts shall be borne exclusively by Tenant), (w) Force Majeure
Costs (as defined in Article 44), (x) the purchase of any furniture, personal property or other non-building system equipment, (y) costs resulting from any default by Tenant of its obligations under this Lease or (z) costs that
are recoverable by Tenant or Landlord from a third party (e.g., insurers, warrantors, or tortfeasors); provided that, with respect to clause (z), Landlord shall be required to use reasonable efforts (short of litigation) to make such
recoveries. Landlord shall not charge Tenant a fee for Landlord’s in-house personnel managing the Tenant Improvements. Tenant shall pay to Landlord, as Additional Rent (as defined below), the amount of the Additional TI Costs incurred by
Landlord in accordance with this Lease amortized over the initial Term at a rate of nine percent (9%). Tenant shall have until December 31, 2013, to incur the unused portion of the TI Costs, after which date Landlord’s obligation to fund
such costs shall expire. To the extent that the total cost of the Tenant Improvements (as shown by reasonably satisfactory supporting documentation provided by Landlord to Tenant) exceeds (such excess, the “Excess TI Costs”) the TI
Costs (or, if Tenant does not elect to send a letter to Landlord in the form of Exhibit D attached hereto, the Base TI Costs), Tenant shall pay such Excess TI Costs within thirty (30) days following the Term Commencement Date. Landlord
shall not be authorized or obligated to incur any portion of the Additional or Excess TI Costs until Landlord shall have received from Tenant a letter in the form attached as Exhibit D hereto executed by an authorized officer of Tenant and
the Additional TI Costs and Excess TI Costs shall be subject to the Budget provisions set forth in the Work Letter; provided, however, that, even if Tenant does not execute a letter in the form of Exhibit D attached hereto, Tenant
shall be liable for Excess TI Costs incurred in accordance with the terms of this Lease, including the Work Letter; and provided, further, that such Excess TI Costs are reflected in the then-current or a succeeding Budget (approved by Tenant,
if required by the terms of the Work Letter). If the cost of the “Tenant Improvements” (as defined in the Office Lease) is less than the “TI Costs” (as defined in the Office Lease), Tenant shall have the right to apply the
difference toward the TI Costs under this Lease. 
 4.5. Warranty. Landlord shall use commercially reasonable efforts to
obtain a customary warranty from Landlord’s contractor permitting Landlord and Tenant to each separately enforce such warranty. Landlord shall use commercially reasonable efforts (but without any obligation to commence or pursue any litigation)
to cause Landlord’s contractor to complete with reasonable promptness the Punchlist Items and repair with reasonable promptness all defects in the construction of the Tenant Improvements in accordance with the Final Plans (as defined in the
Work Letter) as to which Tenant notifies Landlord in writing during the applicable warranty period (“Tenant’s Defect Notice”). 
 5. Condition of Premises. Tenant acknowledges that neither Landlord nor any agent of Landlord has made any representation or warranty with respect to the condition of the Premises or the Project,
or with respect to the suitability of the Premises or the Project for the conduct of Tenant’s business. Except with regard to the Tenant Improvements and as otherwise stated in this Lease, Tenant acknowledges that (a) it is fully familiar
with the condition of the Premises and agrees to take the same in its condition “as is” as of the Term Commencement Date and (b) Landlord shall have no obligation to alter, repair or otherwise prepare the Premises for Tenant’s
occupancy or to pay for or construct any improvements to the Premises. Notwithstanding the foregoing, Landlord shall deliver the Premises to Tenant with (a) the Building systems (i.e., HVAC, plumbing, mechanical, electrical and life safety) in
good working order and condition and (b) the Premises in compliance with the Americans with Disabilities Act, 42 U.S.C. § 12101, et seq. (together with regulations promulgated pursuant thereto, the “ADA”) and all other
Applicable Laws. Tenant’s taking of possession of the Premises shall, except as otherwise agreed to in writing by Landlord and Tenant, conclusively establish that the Premises and the Project were at such time in good, sanitary and satisfactory
condition and repair, subject to any 

  
 5 

 
Punchlist Items and any defects noted in Tenant’s Defect Notice. Costs incurred by Landlord pursuant to this Article 5 shall not be included in TI Costs. 

6. [Intentionally omitted] 
 7. Rentable
Area. 
 7.1. The term “Rentable Area” shall reflect such areas as reasonably calculated by Landlord’s
architect, as the same may be reasonably adjusted from time to time by Landlord in consultation with Landlord’s architect to reflect changes to the Project. 
 7.2. The Rentable Area of the Premises is generally determined by making separate calculations of Rentable Area applicable to each floor within the Premises and totaling the Rentable Area of all floors
within the Premises. The Rentable Area of a floor is computed by measuring to the outside finished surface of the permanent outer Premises walls. The full area calculated as previously set forth is included as Rentable Area, without deduction for
columns and projections or vertical penetrations, including stairs, elevator shafts, flues, pipe shafts, vertical ducts and the like, as well as such items’ enclosing walls. 

7.3. [Intentionally omitted] 
 7.4. The Rentable Area of the Project is the total Rentable Area of all buildings within the Project, excluding the Amenities Building. 

7.5. Review of allocations of Rentable Areas as between tenants of the Building and the Project shall be made as frequently as Landlord
deems appropriate in order to facilitate an equitable apportionment of Operating Expenses (as defined below). If such review is by a licensed architect and allocations are certified by such licensed architect as being correct, then Tenant shall be
bound by such certifications. In the event Landlord modifies the Project by demolishing or otherwise removing from the calculation of the Rentable Area of the Project any material portion of any building, then Tenant’s Pro Rata Share of the
Project shall be appropriately adjusted. 
 8. Rent. 
 8.1. Tenant shall pay to Landlord as Base Rent for the Premises, commencing on the Term Commencement Date, the sums set forth in Section 2.3, subject to the rental adjustments provided in
Article 9 hereof. Base Rent and Additional Rent related to Additional TI Costs shall be paid in equal monthly installments (as set forth in Section 2.3 for Base Rent), subject to the rental adjustments provided in Article 9
hereof, each in advance on the first day of each and every calendar month during the Term. 
 8.2. In addition to Base Rent,
Tenant shall pay to Landlord as additional rent (“Additional Rent”) at times hereinafter specified in this Lease (a) commencing on the Term Commencement Date, Tenant’s pro rata share, as set forth in
Section 2.2 (“Tenant’s Pro Rata Share”), of Operating Expenses (as defined below) and (b) any other amounts that Tenant assumes or agrees to pay under the provisions of this Lease that are owed to Landlord,
including, without limitation, any and all other sums that may become due by reason of any default of Tenant or failure on Tenant’s part to comply with the agreements, terms, covenants and conditions of this Lease to be performed by Tenant,
after notice and the lapse of any applicable cure periods. 
 8.3. Base Rent, Additional Rent related to Additional TI Costs and
all other Additional Rent shall together be denominated “Rent.” Rent shall be paid to Landlord, without abatement, deduction or offset (except as expressly provided in Articles 25 and 26 herein), in lawful money of the
United States of America at the office of Landlord as set forth in Section 2.8 or to such other person or at such other place as Landlord may from time designate in writing. In the event the Term commences or ends on a day other than the
first day of a calendar month, then the Rent for such fraction of a month shall be prorated for such period on the basis of a thirty (30) day month and shall be paid at the then-current rate for such fractional month. 

  
 6 

 9. Rent Adjustments. Base Rent and Additional Rent related to Additional TI
Costs shall be subject to an annual upward adjustment of three and twenty-five hundredths percent (3.25%) of the then-current Base Rent, with the first (1st) such adjustment occurring on the first (1st) day of the twenty-fifth (25th) month of the Term. The first such adjustment shall become effective commencing with that monthly rental
installment that is due on or after the second
(2nd) annual anniversary of the Term Commencement
Date (i.e., at the beginning of the twenty-fifth
(25th) month of the Term), and subsequent adjustments
shall become effective on every successive annual anniversary for so long as this Lease continues in effect. 
 10. Operating Expenses.

 10.1. As used herein, the term “Operating Expenses” shall include: 

(a) Government impositions including, without limitation, property tax costs consisting of real and personal property taxes and
assessments, including amounts due under any improvement bond upon the Building or the Project, including the parcel or parcels of real property upon which the Building and areas serving the Building are located or assessments in lieu thereof
imposed by any federal, state, regional, local or municipal governmental authority, agency or subdivision (each, a “Governmental Authority”) are levied; taxes on or measured by gross rentals received from the rental of space in the
Project; taxes based on the square footage of the Premises or the Project, as well as any utilities surcharges or any other costs levied, assessed or imposed by, or at the direction of, or resulting from Applicable Laws (as defined below) or
interpretations thereof, promulgated by any Governmental Authority in connection with the use or occupancy of the Project or the parking facilities serving the Project; taxes on this transaction or any document to which Tenant is a party creating or
transferring an interest in the Premises; any fee for a business license to operate an office building; and any expenses, including the reasonable cost of attorneys or experts, reasonably incurred by Landlord in seeking reduction by the taxing
authority of the applicable taxes, less tax refunds obtained as a result of an application for review thereof. Operating Expenses shall not include any net income, franchise, capital stock, estate or inheritance taxes, or taxes that are the personal
obligation of Tenant or of another tenant of the Project or any documentary transfer tax; and 
 (b) All other costs of any kind
paid or incurred by Landlord in connection with the operation or maintenance of the Project (except as solely related to the Building) including, by way of example and not of limitation, costs of repairs and replacements to improvements within the
Project as appropriate to maintain the Project as required hereunder; costs of utilities furnished to the Common Areas; sewer fees; cable television; trash collection; cleaning, including windows; heating; ventilation; air-conditioning; maintenance
of landscaping and grounds; maintenance of drives and parking areas; maintenance of the Amenities Building roof; security services and devices; building supplies; maintenance or replacement of equipment utilized for operation and maintenance of the
Project; license, permit and inspection fees; sales, use and excise taxes on goods and services purchased by Landlord in connection with the operation, maintenance or repair of the Project systems and equipment; telephone, postage, stationery
supplies and other expenses incurred in connection with the operation, maintenance or repair of the Project; accounting, legal and other professional fees and expenses incurred in connection with the Project; costs of furniture, draperies,
carpeting, landscaping and other customary and ordinary items of personal property provided by Landlord for use in Common Areas or in the Project office; Project office rent or rental value for a commercially reasonable amount of space, to the
extent an office used for Project operations is maintained at the Project; capital expenditures (amortized over their useful lives in accordance with generally accepted accounting principles); costs of complying with all federal, state, municipal
and local laws, codes, ordinances, rules and regulations of Governmental Authorities, committees, associations, or other regulatory committees, agencies or governing bodies having jurisdiction over the Property, the Project, the Building, the
Premises, Landlord or Tenant, including both statutory and common law and hazard waste rules and regulations (“Applicable Laws”); costs of maintaining and repairing the Amenities Building; Landlord’s actual expenses associated
with operating and providing the Amenities Building Services, including the fair market rental value of the Amenities Building, net of revenues paid to Landlord with respect to the provision of such services, to the extent that amounts paid by
service providers to Landlord for the right to provide services in the Amenities Building shall be considered revenues from the provision of such services, and the amounts paid by Landlord to induce service providers to provide services in the

  
 7 

 
Amenities Building shall be considered expenses of the provision of such services (all such net costs associated with the Amenities Building, the “Net Amenities Costs”);
insurance premiums, including premiums for public liability, property casualty, earthquake, terrorism and environmental coverages; portions of insured losses paid by Landlord as part of the deductible portion of a loss pursuant to the terms of
insurance policies; service contracts; costs of services of independent contractors retained to do work of a nature referenced above; and costs of compensation (including employment taxes and fringe benefits) of all persons who perform regular and
recurring duties connected with the day-to-day operation and maintenance of the Project, its equipment, the adjacent walks, landscaped areas, drives and parking areas, including, without limitation, janitors, floor waxers, window washers, watchmen,
gardeners, sweepers and handymen. 
 Notwithstanding the foregoing, Operating Expenses shall not include
any leasing commissions; costs, fees or expenses that relate to preparation of rental space for a tenant; expenses of initial development and construction, including, but not limited to, grading, paving, landscaping and decorating (as distinguished
from maintenance, repair and replacement of the foregoing); legal expenses relating to other tenants; costs of repairs to the extent reimbursed by payment of insurance proceeds or warranties received by Landlord; interest upon loans to Landlord or
secured by a mortgage or deed of trust covering the Project or a portion thereof (provided that interest upon a government assessment or improvement bond payable in installments shall constitute an Operating Expense under Subsection
10.1(a)); costs of repairing, maintaining or replacing the Building’s shell, roof, foundation, structural components; costs of maintaining the water-tight integrity of the Building for the first (1st) thirty-six (36) months of the Term; any costs and
expenses relating to the repair, maintenance or replacement of the EFIS system during the first (1st) thirty-six (36) months of the Term; salaries of executive officers of Landlord; depreciation claimed by Landlord for tax purposes (provided that this exclusion of depreciation is not
intended to delete from Operating Expenses actual costs of repairs and replacements that are provided for in Subsection 10.1(b)); taxes that are excluded from Operating Expenses by the last sentence of Subsection 10.1(a); expenses in
connection with services or other benefits of a type that are not provided to Tenant or that are paid directly by Tenant but that are provided by Landlord to another tenant or occupant of the Project (provided that this clause shall not preclude
from Operating Expenses any Operating Expenses related to the Amenities Building); increases in insurance premiums over those in effect on the Term Commencement Date to the extent directly caused by the gross negligence or willful misconduct of
Landlord or any of its employees, agents or contractors; executive salaries or salaries of service personnel to the extent that such salaries are payable in connection with services other than in connection with the management, operation, repair or
maintenance of the Building; the cost of offsite service personnel to the extent that such personnel are not engaged in the management, operation, repair or maintenance of the Project; charitable or political contributions or fees paid to trade
associations; Landlord’s general overhead expenses not related to the Project; overhead profit increments paid to Landlord’s subsidiaries or affiliates for management or other services on or to the Project or for supplies or other
materials to the extent that the cost of the services, supplies or materials materially exceeds the cost that would have been paid had the services, supplies or materials been provided by unaffiliated parties on a competitive basis; loan fees
related to any mortgage or deed of trust; rent and other amounts due under any ground or underlying lease; advertising and promotional expenditures; costs of repairs and other work occasioned by fire, windstorm or other casualty of an insurable
nature of a type for which Landlord is required to carry insurance under the terms of this Lease to the extent Landlord receives insurance proceeds; any costs, fines or penalties incurred due to violations by Landlord of this Lease or any other
lease in the Project, or due to Landlord’s gross negligence or willful misconduct; the cost of correcting any building code or other violations, which violations existed prior to the Term Commencement Date; costs for sculpture, paintings or
other objects of art (and insurance thereon or extraordinary security in connection therewith); wages, salaries or other compensation paid to any executive employees above the grade of building manager; and, for any calendar year, Net Amenities
Costs, to the extent they exceed the Amenities Building Cost Cap. The “Amenities Building Cost Cap” means for the calendar year beginning January 1, 2008, One Hundred Fifty Thousand Dollars ($150,000), and for each calendar
year after the calendar year beginning January 1, 2008, the product of (a) the Amenities Building Cost Cap for the preceding year and (b) the greater of (i) one and (ii) one plus a fraction, the numerator of which is the CPI as
of January 1 of such calendar year and the denominator of which is the CPI as of January 1, 2008. “CPI” means the West Urban Regional Consumer Price Index, for all urban consumers (CPI-U) 

  
 8 

 
for all items other than food and energy, not seasonably adjusted, as published by the United States Department of Labor, Bureau of Labor Statistics (“BLS”); provided,
however, that if said Consumer Price Index shall cease to exist or is changed, then the terms “CPI” or “Consumer Price Index” shall mean such successor index as is designated for such purpose by the BLS, and
if not so designated than such other replacement index as is in the public domain and readily accessible to the general public as Landlord reasonably selects to measure change in purchasing power. Notwithstanding anything to the contrary set forth
herein, Landlord shall not include in Tenant’s Pro Rata Share of Operating Expenses any costs or expenses relating to the Amenities Building until use of the Amenities Building is provided to Tenant. 

Notwithstanding the foregoing, for each calendar year (the “Current Calendar Year”) during the Term
after the first (1st) full calendar year following
the Term Commencement Date, the amount of Tenant’s Pro Rata Share of Operating Expenses, with respect to the Capped Operating Expenses (as defined below) only, shall not exceed one hundred seven percent (107%) of the amount of
Tenant’s Pro Rata Share of Operating Expenses with respect to the Capped Operating Expenses for the immediately proceeding calendar year (the “Preceding Calendar Year”); provided that, for purposes of the foregoing
calculation, if Tenant’s Pro Rata Share increased or decreased during either of such calendar years, then the amount of Tenant’s Pro Rata Share of Capped Operating Expenses for the Preceding Calendar Year shall be adjusted to reflect what
such amounts would have been if Tenant’s Pro Rata Share had been the same during such Preceding Calendar year as they were at the end of the Current Calendar Year. Notwithstanding the foregoing, the aforementioned cap shall not apply to capital
repairs or replacements. “Capped Operating Expenses” means Operating Expenses other than Landlord’s insurance and utility costs and real property taxes on the Project. 

10.2. Tenant shall pay to Landlord on the first day of each calendar month of the Term, as Additional Rent, (a) the Property
Management Fee (as defined below) and (b) Landlord’s estimate of Tenant’s Pro Rata Share of Operating Expenses with respect to the Building and the Project, as applicable, for such month. 

(x) The “Property Management Fee” shall equal two percent (2%) of the Base Rent due from Tenant. 

(y) Within ninety (90) days after the conclusion of each calendar year (or such longer period as may be reasonably required by
Landlord), Landlord shall furnish to Tenant a statement (“Landlord’s Statement”) showing in reasonable detail the actual Operating Expenses and Tenant’s Pro Rata Share of Operating Expenses for the previous calendar year.
Any additional sum due from Tenant to Landlord shall be due and payable within thirty (30) days following Tenant’s receipt of Landlord’s Statement. If the amounts paid by Tenant pursuant to this Section 10.2 exceed
Tenant’s Pro Rata Share of Operating Expenses for the previous calendar year, then Landlord shall credit the difference against the Rent next due and owing from Tenant; provided that, if the Lease term has expired, Landlord shall
accompany said statement with payment for the amount of such difference. 
 (z) Any amount due under this
Section 10.2 for any period that is less than a full month shall be prorated (based on a thirty (30)-day month) for such fractional month. 
 10.3. Landlord’s Statement shall be final and binding upon Tenant unless Tenant, within sixty (60) days after Tenant’s receipt thereof, shall contest any item therein by giving written
notice to Landlord stating Tenant’s reasonable objections to Landlord’s Statement. If, during such sixty (60)-day period, Tenant reasonably and in good faith questions or contests the correctness of Landlord’s statement of
Tenant’s Pro Rata Share of Operating Expenses, Landlord shall provide Tenant with reasonable access to Landlord’s books and records to the extent relevant to determination of Operating Expenses, and such information as Landlord reasonably
determines to be responsive to Tenant’s written inquiries. In the event that, after Tenant’s review of such information, Landlord and Tenant cannot agree upon the amount of Tenant’s Pro Rata Share of Operating Expenses, then Tenant
shall have the right to have an independent public accounting firm hired by Tenant on an hourly basis and not on a contingent-fee basis (at Tenant’s sole cost and expense) and approved by Landlord (which approval Landlord shall not unreasonably
withhold or delay) audit and review such of Landlord’s books and records for the year in question as relate to the determination of Operating Expenses for such year (the 

  
 9 

 
“Independent Review”). Landlord shall make such books and records available at the location where Landlord maintains them in the ordinary course of its business. Landlord need
not provide copies of any books or records but shall permit Tenant to make copies. Tenant shall commence the Independent Review within thirty (30) days after the date Landlord has given Tenant access to Landlord’s books and records for the
Independent Review. Tenant shall complete the Independent Review and notify Landlord in writing of Tenant’s specific objections to Landlord’s calculation of Operating Expenses (including Tenant’s accounting firm’s written
statement of the basis, nature and amount of each proposed adjustment) no later than sixty (60) days after Landlord has first given Tenant access to Landlord’s books and records for the Independent Review. Landlord shall review the results
of any such Independent Review. The parties shall endeavor to agree promptly and reasonably upon Operating Expenses taking into account the results of such Independent Review. If, as of sixty (60) days after Tenant has submitted the Independent
Review to Landlord, the parties have not agreed on the appropriate adjustments to Operating Expenses, then the parties shall engage a mutually agreeable independent third party accountant with at least ten (10) years’ experience in
commercial real estate accounting in the Silicon Valley, California, area (the “Accountant”). If the parties cannot agree on the Accountant, each shall within ten (10) days after such impasse appoint an Accountant (different
from the accountant and accounting firm that conducted the Independent Review) and, within ten (10) days after the appointment of both such Accountants, those two Accountants shall select a third (which cannot be the accountant and accounting firm
that conducted the Independent Review). If either party fails to timely appoint an Accountant, then the Accountant the other party appoints shall be the sole Accountant. Within ten (10) days after appointment of the Accountant(s), Landlord and
Tenant shall each simultaneously give the Accountants (with a copy to the other party) its determination of Operating Expenses, with such supporting data or information as each submitting party determines appropriate. Within ten (10) days after
such submissions, the Accountants shall by majority vote select either Landlord’s or Tenant’s determination of Operating Expenses. The Accountants may not select or designate any other determination of Operating Expenses. The determination
of the Accountant(s) shall bind the parties. If the parties agree or the Accountant(s) determine that Tenant’s Pro Rata Share of Operating Expenses actually paid for the calendar year in question exceeded Tenant’s obligations for such
calendar year, then Landlord shall, at Tenant’s option, either (a) credit the excess to the next succeeding installments of estimated Additional Rent or (b) pay the excess to Tenant within thirty (30) days after delivery of such
results. If the parties agree or the Accountant(s) determine that Tenant’s Pro Rata Share of Operating Expenses actually paid for the calendar year in question exceeded Tenant’s obligations for such calendar year by more than five percent
(5%), then Landlord shall pay the cost of the Accountant(s). If the parties agree or the Accountant(s) determine that Tenant’s payments of Tenant’s Pro Rata Share of Operating Expenses for such calendar year were less than Tenant’s
obligation for the calendar year, then Tenant shall pay the deficiency to Landlord within thirty (30) days after delivery of such results. 
 10.4. Except as provided in Section 4.2 above, Tenant shall not be responsible for Operating Expenses attributable to the time period prior to the Term Commencement Date. Tenant’s
responsibility for Tenant’s Pro Rata Share of Operating Expenses shall continue to the later of (a) the date of termination of the Lease and (b) the date Tenant has fully vacated the Premises; provided that nothing in this
Section 10.4 shall in any way limit Landlord’s remedies under Article 32. 
 10.5. Operating Expenses
for the calendar year in which Tenant’s obligation to share therein commences and for the calendar year in which such obligation ceases shall be prorated on a 365-day basis. Expenses such as taxes, assessments and insurance premiums that are
incurred for an extended time period shall be prorated based upon the time periods to which they apply so that the amounts attributed to the Premises relate in a reasonable manner to the time period wherein Tenant has an obligation to share in
Operating Expenses. 
 10.6. Within three (3) business days after the end of each calendar month, Tenant shall submit to
Landlord an invoice, or, in the event an invoice is not available, an itemized list, of all costs and expenses that (a) Tenant has incurred (either internally or by employing third parties) during the prior month and (b) for which Tenant
reasonably believes it is entitled to reimbursements from Landlord pursuant to the terms of this Lease or that Tenant reasonably believes is the responsibility of Landlord pursuant to this Lease or the Work Letter. 

  
 10 

 11. Taxes on Tenant’s Property. 

11.1. Commencing on the Term Commencement Date, Tenant shall pay prior to delinquency any and all taxes levied against any personal
property or trade fixtures placed by Tenant in or about the Premises. 
 11.2. If any such taxes on Tenant’s personal
property or trade fixtures are levied against Landlord or Landlord’s property or, if the assessed valuation of the Building or the Property is increased by inclusion therein of a value attributable to Tenant’s personal property or trade
fixtures, and if Landlord, after written notice to Tenant, pays the taxes based upon any such increase in the assessed valued of the Building or the Project, then Tenant shall, upon demand, repay to Landlord the taxes so paid by Landlord.

 11.3. If any improvements in or alterations to the Premises, whether owned by Landlord or Tenant and whether or not affixed
to the real property so as to become a part thereof, are assessed for real property tax purposes at a valuation higher than the valuation at which improvements conforming to Landlord’s building standards (the “Building
Standard”) in other spaces in the Project are assessed, then the real property taxes and assessments levied against Landlord or the Building by reason of such excess assessed valuation shall be deemed to be taxes levied against personal
property of Tenant and shall be governed by the provisions of Section 11.2. Any such excess assessed valuation due to improvements in or alterations to space in the Project leased by other tenants of Landlord shall not be included in the
Operating Expenses defined in Article 10, but shall be treated, as to such other tenants, as provided in this Section 11.3. If the records of the County Assessor are available and sufficiently detailed to serve as a basis for
determining whether said Tenant improvements or alterations are assessed at a higher valuation than the Building Standard, then such records shall be binding on both Landlord and Tenant. 
 12. Security Deposit. 
 12.1. On the Term Commencement Date, Tenant shall
deposit with Landlord the sum set forth in Section 2.6 (the “Security Deposit”), which sum shall be held by Landlord as security for the faithful performance by Tenant of all of the terms, covenants and conditions of
this Lease to be kept and performed by Tenant during the period commencing on the Execution Date and ending upon the expiration or termination of this Lease. If Tenant defaults with respect to any provision of this Lease beyond the applicable notice
and cure period (if any), including, but not limited to, any provision relating to the payment of Rent, then Landlord may (but shall not be required to) use, apply or retain all or any part of the Security Deposit for the payment of any Rent or any
other sum in default, or to compensate Landlord for any other loss or damage that Landlord may suffer by reason of Tenant’s default. If any portion of the Security Deposit is so used or applied, then Tenant shall, within ten (10) days
following demand therefor, deposit cash with Landlord in an amount sufficient to restore the Security Deposit to its original amount, and Tenant’s failure to do so shall be a material breach of this Lease. The provisions of this Article
12 shall survive the expiration or earlier termination of this Lease. TENANT HEREBY WAIVES THE REQUIREMENTS OF SECTION 1950.7 OF THE CALIFORNIA CIVIL CODE, AS THE SAME MAY BE AMENDED FROM TIME TO TIME. 

12.2. In the event of bankruptcy or other debtor-creditor proceedings against Tenant, the Security Deposit shall be deemed to be applied
first to the payment of Rent and other charges due Landlord for all periods prior to the filing of such proceedings. 
 12.3.
Landlord may deliver to any purchaser of Landlord’s interest in the Premises the funds deposited hereunder by Tenant, and provided the purchaser assumes Landlord’s obligations hereunder, Landlord shall be discharged from any further
liability with respect to such deposit. This provision shall also apply to any subsequent transfers. 
 12.4. The Security
Deposit, or any balance thereof remaining after deductions properly made by Landlord pursuant to this Lease, shall be returned to Tenant (or, at Landlord’s option, to the last assignee of Tenant’s interest hereunder) within thirty
(30) days after the expiration or earlier termination of this Lease. 

  
 11 

 12.5. Provided that Tenant is not then in default under this Lease, Landlord shall
return Seventy-Five Thousand Dollars ($75,000) of the Security Deposit to Tenant (or offset the same against the next payment of Rent owing from Tenant) on each annual anniversary of the Term Commencement Date until the Security Deposit required
under this Lease equals Four Hundred Thousand Dollars ($400,000). In no event shall the required Security Deposit be less than Four Hundred Thousand Dollars ($400,000). 
 12.6. If the Security Deposit shall be in cash, Landlord shall hold the Security Deposit in an account at a banking organization selected by Landlord; provided, however, that Landlord shall not be
required to maintain a separate account for the Security Deposit, but may intermingle it with other funds of Landlord. Landlord shall be entitled to all interest and/or dividends, if any, accruing on the Security Deposit. Landlord shall not be
required to credit Tenant with any interest for any period during which Landlord does not receive interest on the Security Deposit. 
 12.7. The Security Deposit may be in the form of cash, a letter of credit or any other security instrument acceptable to Landlord in its sole discretion. Tenant may at any time, except during Default (as
defined below), deliver a letter of credit (the “L/C Security”) as the entire Security Deposit, as follows. 

(a) If Tenant elects to deliver L/C Security, then Tenant shall provide Landlord, and maintain in full force and effect throughout the
Term, a letter of credit in the form of Exhibit E issued by an issuer reasonably satisfactory to Landlord, in the amount of the Security Deposit, with an initial term of at least one year. If, at the Term Expiration Date, any Rent remains
uncalculated or unpaid, then: (i) Landlord shall with reasonable diligence complete any necessary calculations; (ii) Tenant shall extend the expiry date of such L/C Security from time to time as Landlord reasonably requires; and
(iii) in such extended period, Landlord shall not unreasonably refuse to consent to an appropriate reduction of the L/C Security. Tenant shall reimburse Landlord’s legal costs (as estimated by Landlord’s counsel) in handling
Landlord’s acceptance of L/C Security or its replacement or extension. 
 (b) If Tenant delivers to Landlord satisfactory
L/C Security in place of the entire Security Deposit, Landlord shall remit to Tenant any cash Security Deposit Landlord previously held. If Tenant delivers to Landlord cash in the amount of the Security Deposit, Landlord shall return to Tenant any
L/C Security previously held. 
 (c) Landlord may draw upon the L/C Security, and hold and apply the proceeds in the same manner
and for the same purposes as the Security Deposit, if: (i) an uncured Default (as defined below) exists; (ii) as of the date forty-five (45) days before any L/C Security expires (even if such scheduled expiry date is after the Term
Expiration Date) Tenant has not delivered to Landlord an amendment or replacement for such L/C Security, reasonably satisfactory to Landlord, extending the expiry date to the earlier of (1) six (6) months after the then-current Term
Expiration Date or (2) the date one year after the then-current expiry date of the L/C Security; (iii) the L/C Security provides for automatic renewals, Landlord asks the issuer to confirm the current L/C Security expiry date, and the
issuer fails to do so within ten (10) business days; (iv) Tenant fails to pay (when and as Landlord reasonably requires) any bank charges for Landlord’s transfer of the L/C Security; or (v) the issuer of the L/C Security ceases,
or announces that it will cease, to maintain an office in the city where Landlord may present drafts under the L/C Security and Tenant does not replace the L/C Security with a new L/C Security acceptable to Landlord at least ten (10) days prior
to the date on which such cessation occurs. This paragraph does not limit any other provisions of this Lease allowing Landlord to draw the L/C Security under specified circumstances. 

(d) Tenant shall not seek to enjoin, prevent, or otherwise interfere with Landlord’s draw under L/C Security, even if it violates
this Lease. Tenant acknowledges that the only effect of a wrongful draw would be to substitute a cash Security Deposit for L/C Security, causing Tenant no legally recognizable damage. Landlord shall hold the proceeds of any draw in the same manner
and for the same purposes as a cash Security Deposit. In the event of a wrongful draw, the parties shall cooperate to allow Tenant to post replacement L/C Security simultaneously with the return to Tenant of the wrongfully drawn sums, and Landlord
shall upon request confirm in writing to the issuer of the L/C Security that Landlord’s draw was erroneous. 

  
 12 

 (e) If Landlord transfers its interest in the Premises, then Tenant shall at Tenant’s
expense, within five (5) Business Days after receiving a request from Landlord, deliver (and, if the issuer requires, Landlord shall consent to) an amendment to the L/C Security naming Landlord’s grantee as substitute beneficiary. If the
required Security changes while L/C Security is in force, then Tenant shall deliver (and, if the issuer requires, Landlord shall consent to) a corresponding amendment to the L/C Security. 
 13. Use. 
 13.1. Tenant may use the Premises for the purpose set forth in
Section 2.7, and shall not use the Premises, or (commencing on the Term Commencement Date) permit or suffer the Premises to be used, for any other purpose without Landlord’s prior written consent, which consent Landlord may withhold
in its sole and absolute discretion. 
 13.2. Tenant shall not use or occupy the Premises in violation of Applicable Laws;
zoning ordinances; or the certificate of occupancy issued for the Premises, and shall, upon five (5) days’ written notice from Landlord, discontinue any use of the Premises that is declared or claimed by any Governmental Authority having
jurisdiction to be a violation of any of the above, or that in Landlord’s reasonable opinion violates any of the above. Tenant shall comply with any direction of any Governmental Authority having jurisdiction that shall, by reason of the nature
of Tenant’s use or occupancy of the Premises, impose any duty upon Tenant or Landlord with respect to the Premises or with respect to the use or occupation thereof. 
 13.3. Tenant shall not do or (commencing on the Term Commencement Date) permit to be done anything that will invalidate or increase the cost of any fire, environmental, extended coverage or any other
insurance policy covering the Building and the Project, and shall comply with all rules, orders, regulations and requirements of the insurers of the Building and the Project, and Tenant shall promptly, upon demand and commencing on the Term
Commencement Date, reimburse Landlord for any additional premium charged for such policy by reason of Tenant’s failure to comply with the provisions of this Article 13. 

13.4. From and after the Term Commencement Date, Tenant shall keep all doors opening onto public areas closed, except when in use for
ingress and egress. 
 13.5. No additional locks or bolts of any kind shall be placed upon any of the doors or windows by
Tenant, nor shall any changes be made to existing locks or the mechanisms thereof without Landlord’s prior written consent. Tenant shall, upon termination of this Lease, return to Landlord all keys to offices and restrooms either furnished to
or otherwise procured by Tenant. In the event any key so furnished to Tenant is lost, Tenant shall pay to Landlord the cost of replacing the same or of changing the lock or locks opened by such lost key if Landlord shall deem it necessary to make
such change. Notwithstanding anything in this Section 13.5 to the contrary, except in the case of an emergency, Landlord shall not enter the Premises unescorted by an employee or agent of Tenant; provided that Tenant shall make an
employee or agent reasonably available. 
 13.6. No awnings or other projections shall be attached to any outside wall of the
Building without Landlord’s prior written consent. With respect to the office portion of the Premises, no curtains, blinds, shades or screens shall be attached to or hung in, or used in connection with, any window or door of the Premises other
than Landlord’s standard window coverings, and neither the interior nor exterior of any windows shall be coated or otherwise sunscreened without Landlord’s prior written consent. 

13.7. No sign, advertisement or notice (“Signage”) shall be exhibited, painted or affixed by Tenant on or visible from
the outside of the Building without Landlord’s prior written consent. Commencing on the Term Commencement Date, Tenant shall have Signage rights for the Premises substantially consistent with the Signage permitted for other comparable Tenants
in the Project, as Landlord reasonably determines. At Landlord’s option, Landlord may install any such Signage, and Tenant shall pay all costs associated with such installation within five (5) days after the Term Commencement Date.

  
 13 

 13.8. Tenant shall only place equipment within the Premises with floor loading consistent
with the structural design of the Building without Landlord’s prior written approval, and such equipment shall be placed in a location designed to carry the weight of such equipment. 

13.9. [Intentionally omitted] 
 13.10. Tenant shall not (a) do or (commencing on the Term Commencement Date) permit anything to be done in or about the Premises that shall unreasonably obstruct or interfere with the rights of other
tenants or occupants of the Project, or injure or annoy them, (b) use or (commencing on the Term Commencement Date) allow the Premises to be used for immoral, unlawful or objectionable purposes, (c) cause, maintain or (commencing on the
Term Commencement Date) permit any nuisance or waste in, on or about the Premises or the Project or (d) take any other action that would in Landlord’s reasonable determination in any manner adversely affect other tenants’ quiet use
and enjoyment of their space or adversely impact their ability to conduct business in a professional and suitable work environment. 
 13.11. Subject to Landlord’s obligations expressly set forth herein, including without limitation Landlord’s obligation to construct the Tenant Improvements in compliance with Applicable Laws,
commencing on the Term Commencement Date Tenant shall be responsible for all liabilities, costs and expenses arising out of or in connection with the compliance of the Premises becoming out of compliance with the ADA after the Term Commencement
Date, and Tenant shall indemnify, save, defend and hold Landlord harmless from and against any loss, cost, liability or expense (including reasonable attorneys’ fees and disbursements) arising out of the failure of Tenant to comply with this
Section 13.11. The indemnity provisions of this Section 13.11 shall survive the expiration or earlier termination of this Lease as to events occurring during the Term. 
 14. Rules and Regulations, CC&Rs, Parking Facilities and Common Areas. 

14.1. Tenant shall have the non-exclusive right, in common with others, to use the Common Areas, subject to the rules and regulations
adopted by Landlord and attached hereto as Exhibit F, together with such other reasonable and nondiscriminatory rules and regulations as are hereafter promulgated by Landlord in its reasonable discretion (the “Rules and
Regulations”). Tenant shall faithfully observe and comply with the Rules and Regulations. Landlord shall not be responsible to Tenant for the violation or non-performance by any other tenant or any agent, employee or invitee thereof of any
of the Rules and Regulations. 
 14.2. This Lease is subject to any recorded covenants, conditions or restrictions on the
Project or Property (the “CC&Rs”). Tenant shall comply with the CC&Rs. 
 14.3. Tenant shall have a
non-exclusive license during the Term to use Tenant’s Pro Rata Share of parking facilities (up to three and two tenths (3.2) spaces per one thousand (1,000) rentable square feet) serving the Project in common on an unreserved basis
with other tenants of the Project at no additional cost to Tenant. In addition, Landlord shall, at Tenant’s sole cost and expense, designate the ten (10) parking spaces shown in Exhibit K attached hereto (which spaces shall be part
of, and not in addition to, the spaces described in the preceding sentence) as Tenant’s reserved visitor parking. 
 14.4.
Nothing in this Article 14 is intended to create an affirmative duty on Landlord’s part to monitor parking. 
 14.5.
Landlord reserves the right to make reasonable modifications to the Common Areas, including the right to add or remove exterior landscaping and to subdivide real property. 
 14.6. Exhibit L attached hereto depicts where the exterior equipment yard, back-up generator pad, covered loading dock and dining patio shall be located, subject to the approval of the applicable
Governmental Authorities. Nothing in this Section 14.6 shall obligate Landlord to monitor potential use of the dining patio by third parties. 

  
 14 

 15. Project Control by Landlord. 

15.1. Landlord reserves full control over the Building and the Project to the extent not inconsistent with Tenant’s enjoyment of the
Premises as provided by this Lease. This reservation includes, without limitation, Landlord’s right to subdivide the Project, convert the Building and other buildings within the Project to condominium units, grant easements and licenses to
third parties, and maintain or establish ownership of the Building separate from fee title to the Property. 
 15.2.
[Intentionally omitted] 
 15.3. Tenant shall, at Landlord’s request, promptly execute such further documents as may be
reasonably appropriate to assist Landlord in the performance of its obligations hereunder; provided that Tenant need not execute any document that creates additional liability for Tenant or that deprives Tenant of the quiet enjoyment and use
of the Premises as provided for in this Lease and materially affects any rights or remedies hereunder; provided, however, that nothing in this Section 15.3 shall relieve Tenant of its obligations under Article 31. 

15.4. Subject to the provisions of Section 13.5 above, Landlord may, at any and all reasonable times during non-business
hours (or during business hours if Tenant so requests), and upon twenty-four (24) hours’ prior notice (provided that no time restrictions shall apply or advance notice be required if an emergency necessitates immediate entry), enter
the Premises to (a) inspect the same and to determine whether Tenant is in compliance with its obligations hereunder, (b) supply any service Landlord is required to provide hereunder, (c) show the Premises to prospective purchasers or
tenants during the final year of the Term, (d) post notices of nonresponsibility and (e) access the telephone equipment, electrical substation and fire risers. In connection with any such alteration, improvement or repair as described in
this Section 15.4, Landlord may erect in the Premises or elsewhere in the Project scaffolding and other structures reasonably required for the alteration, improvement or repair work to be performed. In no event shall Tenant’s Rent
abate as a result of Landlord’s activities pursuant to this Section 15.4; provided, however, that all such activities shall be conducted in such a manner so as to cause as little interference to Tenant as is reasonably
possible. Landlord shall at all times retain a key with which to unlock all of the doors in the Premises. If an emergency necessitates immediate access to the Premises, Landlord may use whatever force is necessary to enter the Premises, and any such
entry to the Premises shall not constitute a forcible or unlawful entry to the Premises, a detainer of the Premises, or an eviction of Tenant from the Premises or any portion thereof. 
 16. Quiet Enjoyment. So long as Tenant is not in Default under this Lease, Landlord or anyone acting through or under Landlord shall not disturb Tenant’s occupancy of the Premises, except as
permitted by this Lease. 
 17. Utilities and Services. 
 17.1. Commencing on the Term Commencement Date, Tenant shall pay for all water (including the cost to service, repair and replace reverse osmosis, de-ionized and other treated water), gas, heat, light,
power, telephone, internet service, cable television, other telecommunications and other utilities supplied to the Premises, together with any fees, surcharges and taxes thereon. If any such utility is not separately metered to Tenant, Tenant shall
pay a reasonable proportion (to be determined by Landlord) of all charges of such utility jointly metered with other premises as part of Tenant’s Pro Rata Share of Operating Expenses or, in the alternative, Landlord may, at its option, monitor
the usage of such utilities by Tenant and charge Tenant with the cost of purchasing, installing and monitoring such metering equipment, which cost shall be paid by Tenant as Additional Rent. Tenant shall contract directly with the relevant providers
for gas, water for the Premises, telephone (other than for the elevator and fire alarm system), internet service, cable television and other telecommunications. Throughout the duration of Tenant’s occupancy of the Premises, Tenant shall keep
the Premises’ gas and water meters and installation equipment in good working order and repair at Tenant’s sole cost and expense. If Tenant fails to so maintain such meters and equipment, Landlord may repair or replace the same and shall
collect the costs therefor from Tenant. Tenant agrees to pay for water and gas consumed, as shown on said meter, and for the other utilities for which Tenant directly contracts with the applicable suppliers, as and when bills are rendered. If Tenant
fails to timely make such payments, Landlord may pay such charges and collect the same from Tenant. Any 

  
 15 

 
such costs or expenses incurred, or payments made by Landlord for any of the reasons or purposes hereinabove stated, shall be deemed to be Additional Rent payment by Tenant and collectible by
Landlord as such. 
 17.2. Landlord shall not be liable for, nor shall any eviction of Tenant result from, the failure to
furnish any utility or service, whether or not such failure is caused by Force Majeure. In the event of such failure, Tenant shall not be entitled to termination of this Lease or any abatement or reduction of Rent, nor shall Tenant be relieved from
the operation of any covenant or agreement of this Lease except as expressly provided in Articles 25 and 26 herein. 
 17.3. Tenant shall pay for, prior to delinquency of payment therefor, any utilities and services that may be furnished to the Premises during or, if Tenant occupies the Premises after the expiration or
earlier termination of the Term, after the Term. 
 17.4. [Intentionally omitted] 

17.5. [Intentionally omitted] 
 17.6. Utilities and services provided by Landlord to the Premises that are separately metered shall be paid by Tenant directly to the supplier of such utility or service. 

17.7. Landlord shall provide water to the Common Areas. Landlord shall wash the exterior of the Building’s windows not less than
twice during every twelve (12) month period. 
 17.8. It is expressly understood and agreed that any covenants on
Landlord’s part to furnish any service pursuant to any of the terms, covenants, conditions, provisions or agreements of this Lease, or to perform any act or thing for the benefit of Tenant, shall not be deemed breached if Landlord is unable to
furnish or perform the same by virtue of Force Majeure. 
 18. Alterations. 

18.1. Tenant shall make no alterations, additions or improvements in or to the Premises or engage in any construction, demolition,
reconstruction, renovation, or other work (whether major or minor) of any kind in, at, or serving the Premises (“Alterations”) without Landlord’s prior written approval, which approval Landlord shall not unreasonably withhold;
provided, however, that in the event any proposed Alteration affects (a) any structural portions of the Building, including exterior walls, roof, foundation or core of the Building, (b) the exterior of the Building or (c) any
Building systems, including elevator, plumbing, air conditioning, heating, electrical, security, life safety and power, then Landlord may withhold its approval with respect thereto in its sole and absolute discretion; and provided, further,
that Landlord’s consent shall not be required (but Tenant shall be required to provide Landlord with prior written notice and to comply with all other provisions of this Article 18) for any Alterations or set of Alterations costing less
than One Hundred Thousand Dollars ($100,000). Tenant shall, in making any such Alterations, use only those architects, contractors, suppliers and mechanics of which Landlord has given prior written approval, which approval shall be in
Landlord’s reasonable discretion. In seeking Landlord’s approval, Tenant shall provide Landlord, at least fourteen (14) days in advance of any proposed construction, with plans, specifications, bid proposals, work contracts, requests
for laydown areas and such other information concerning the nature and cost of the Alterations as Landlord may reasonably request. 
 18.2. Tenant shall not construct or permit to be constructed partitions or other obstructions that might interfere with free access to mechanical installation or service facilities of the Building, or
interfere with the moving of Landlord’s equipment to or from the enclosures containing such installations or facilities. 

18.3. Tenant shall coordinate reasonably with Landlord’s property management office in scheduling all work to be performed for or by
Tenant. 
 18.4. Tenant covenants and agrees that all work done by Tenant or Tenant’s contractors shall be performed in
full compliance with Applicable Laws. Within thirty (30) days after completion of any Alterations, Tenant shall provide Landlord with complete “as-built” drawing 

  
 16 

 
print sets and electronic CADD files on disc (or files in such other current format in common use as Landlord reasonably approves or requires) showing any changes in the Premises. 

18.5. Before commencing any Alterations costing in excess of Twenty-Five Thousand Dollars ($25,000), Tenant shall give Landlord at least
fourteen (14) days’ prior written notice of the proposed commencement of such work. 
 18.6. Other than Tenant’s
Property (as defined in Section 18.8 below), all Tenant Improvements, Alterations, fixtures, additions and improvements, subject to Section 18.8, attached to or built into the Premises, made by either of the Parties,
including, without limitation, all floor and wall coverings, built-in cabinet work and paneling, sinks and related plumbing fixtures, laboratory benches, exterior venting fume hoods and walk-in freezers and refrigerators, ductwork, conduits,
electrical panels and circuits, shall (unless, prior to such construction or installation, Landlord elects otherwise) become the property of Landlord upon the expiration or earlier termination of the Term, and shall remain upon and be surrendered
with the Premises as a part thereof. The Premises shall at all times remain the property of Landlord and shall be surrendered to Landlord upon the expiration or earlier termination of this Lease. 

18.7. Tenant shall repair any damage to the Premises caused by Tenant’s removal of any property from the Premises. During any such
restoration period, Tenant shall pay Rent to Landlord as provided herein as if said space were otherwise occupied by Tenant. The provisions of this Section shall survive the expiration or earlier termination of this Lease. Tenant shall have no
obligation to remove any Alterations at the end of the Term unless Landlord, concurrently with giving its consent to such Alterations (at the written request of Tenant) notifies Tenant in writing that removal and restoration of such Alterations
shall be required. Tenant shall not be required to remove any initial Tenant Improvements. 
 18.8. For purposes of this
Article 18, “Tenant’s Property” shall mean all moveable furniture, trade fixtures, equipment and personal property that were supplied by or paid for by Tenant. Tenant’s Property shall include, without limitation,
those items listed on Exhibit H attached hereto (as the same may be updated from time to time with the reasonable consent of both parties). If Tenant shall fail to remove any of its effects from the Premises prior to termination of this
Lease, then Landlord may, at its option, remove the same in any manner that Landlord shall choose and store said effects without liability to Tenant for loss thereof or damage thereto, and Tenant shall pay Landlord, upon demand, any costs and
expenses incurred due to such removal and storage or Landlord may, at its sole option and without notice to Tenant, sell such property or any portion thereof at private sale and without legal process for such price as Landlord may obtain and apply
the proceeds of such sale against any (a) amounts due by Tenant to Landlord under this Lease and (b) any expenses incident to the removal, storage and sale of said personal property. 

18.9. Other than Tenant’s Property, in no event shall Tenant remove any improvement from the Premises as to which Landlord
contributed payment, including, without limitation, the Tenant Improvements made pursuant to the Work Letter without Landlord’s prior written consent, which consent Landlord may withhold in its sole and absolute discretion. 

18.10. Tenant shall pay to Landlord in relation to all changes installed by Tenant or its contractors or agents all of Landlord’s
actual third party costs for plan review, coordination, scheduling and supervision thereof. Tenant shall reimburse Landlord for any extra expenses incurred by Landlord by reason of faulty work done by Tenant or its contractors, or by reason of
delays caused by such work, or by reason of inadequate clean-up. 
 18.11. Within sixty (60) days after final completion of
Alterations performed by Tenant with respect to the Premises, Tenant shall submit to Landlord documentation showing the amounts expended by Tenant with respect to such Alterations performed by Tenant together with supporting documentation reasonably
acceptable to Landlord. 
 18.12. Tenant shall require its contractors and subcontractors performing work on the Premises to
name Landlord and its affiliates and lenders as additional insureds on their respective insurance policies. 

  
 17 

 19. Repairs and Maintenance. 

19.1. Following the Term Commencement Date, Tenant, at its sole cost and expense, shall maintain and keep the
Premises (except Landlord’s Items) in good condition and in a manner consistent with the Permitted Use. Tenant shall make all repairs, replacements and improvements (except with respect to Landlord’s Items), including, without limitation,
all HVAC, plumbing and electrical repairs, replacements and improvements required, and shall keep the same free and clear from all rubbish and debris. All repairs made by Tenant shall be at least equal in quality to the original work, and shall be
made only by Tenant’s employees (provided they are qualified to perform such repairs and maintenance, do not void any warranties on the Building’s equipment, and perform the repairs in accordance with Applicable Laws) or by a
licensed, bonded contractor approved in advance by Landlord; provided, however, that such contractor need not be bonded or approved by Landlord if the non-structural alterations, repairs, additions or improvements to be performed do not
exceed Twenty-Five Thousand Dollars ($25,000) in value. Landlord may impose reasonable restrictions and requirements with respect to such repairs. Tenant shall not take or fail to take any action, the taking or failure of which shall cause waste,
damage or injury to the Premises. Tenant shall indemnify, save, defend (by legal counsel acceptable to Landlord) and hold harmless Landlord from and against any and all Claims (as defined below) arising out of the failure of Tenant or Tenant’s
Agents to perform the covenants contained in this paragraph. “Tenant’s Agents” shall be defined to include Tenant’s officers, employees, agents, contractors, invitees, customers and subcontractors. Landlord shall repair
and maintain the Common Areas of the Project, the structural and exterior portions of the Building (including, without limitation, the Building’s shell, roof, foundation, structural components and windows), the BMS system (only in regards to
the BMS system’s ability to measure the utilities entering the Building, and provided Tenant shall have secure online access to monitor and control Tenant’s system) elevators, fire sprinkler systems, fire alarm panels, elevator and
fire alarm telephone lines (collectively, “Landlord’s Items”). Except as otherwise stated in Section 10.1(b), any costs related to the repair or maintenance activities specified in this Section 19.1
shall be included as a part of Operating Expenses, unless such repairs or maintenance is required in whole or in part because of any act, neglect, fault or failure to act of Tenant, its agents, servants, employees or invitees, in which case Tenant
shall pay to Landlord the cost of such repairs and maintenance; provided, however, that costs related to window repairs and maintenance to protect against water intrusion after the first (1st) thirty-six (36) months following the Term Commencement
Date shall constitute an Operating Expense. 
 19.2. Except for services of Landlord, if any, required by
Section 19.1, following the Term Commencement Date, Tenant shall at Tenant’s sole cost and expense maintain and keep the Premises (except Landlord’s Items) and every part thereof in good condition and repair, damage thereto
from ordinary wear and tear and casualty and condemnation excepted. Tenant shall, upon the expiration or sooner termination of the Term, surrender the Premises (except with respect to Landlord’s Items) to Landlord in as good of a condition as
when received, ordinary wear and tear and casualty and condemnation excepted; and shall, at Landlord’s request, remove all telephone and data systems, wiring and equipment from the Premises, and repair any damage to the Premises caused thereby.
Landlord shall have no obligation to alter, remodel, improve, repair, decorate or paint the Premises or any part thereof, other than pursuant to the terms and provisions of the Work Letter and with respect to Landlord’s Items. 

19.3. Landlord shall not be liable for any failure to make any repairs or to perform any maintenance that is an obligation of Landlord
unless such failure shall persist for an unreasonable time after Tenant provides Landlord with written notice of the need of such repairs or maintenance. Tenant waives its rights under Applicable Laws now or hereafter in effect to make repairs at
Landlord’s expense. If Tenant shall fail, after reasonable notice, to maintain or to commence and thereafter to proceed with diligence to make any repair required of it pursuant to the terms of this Lease, Landlord, without being under any
obligation to do so and without thereby waiving such default by Tenant, may so maintain or make such repair and may charge Tenant for the costs thereof. Any expense reasonably incurred by Landlord in connection with the making of such repairs may be
billed by Landlord to Tenant monthly or, at Landlord’s option, immediately, and shall be due and payable within ten (10) days after such billing or, at Landlord’s option, may be deducted from the Security Deposit. 

  
 18 

 19.4. Repairs under this Article 19 that are obligations of Landlord are subject to
allocation among Tenant and other tenants as Operating Expenses, except as otherwise provided in this Article 19. 

19.5. This Article 19 relates to repairs and maintenance arising in the ordinary course of operation of the Building and the
Project and any related facilities. In the event of fire, earthquake, flood, vandalism, war, terrorism, natural disaster or similar cause of damage or destruction, Article 25 shall apply in lieu of this Article 19. 

19.6. If any excavation shall be made upon land adjacent to or under the Building, or shall be authorized to be made, Tenant shall afford
to the person causing or authorized to cause such excavation, license to enter the Premises for the purpose of performing such work as said person shall deem necessary or desirable to preserve and protect the Building from injury or damage and to
support the same by proper foundations, without any claim for damages or liability against Landlord and without reducing or otherwise affecting Tenant’s obligations under this Lease. 

19.7. Landlord and Landlord’s agents shall have the right to enter upon the Premises or any portion thereof for the purposes of
performing any repairs or maintenance Landlord is permitted to make pursuant to this Lease, and of ascertaining the condition of the Premises or whether Tenant is observing and performing Tenant’s obligations hereunder, all without unreasonable
interference from Tenant or Tenant’s Agents. Notwithstanding anything in this Section 19.7 to the contrary, except in the case of an emergency, Landlord shall not enter the Premises unescorted by an employee or agent of Tenant;
provided that Tenant shall make an employee or agent reasonably available. 
 20. Liens. 

20.1. Subject to the immediately succeeding sentence, Tenant shall keep the Premises and the Project free from any liens arising out of
work performed, materials furnished or obligations incurred by Tenant. Tenant further covenants and agrees that any mechanic’s lien filed against the Premises or the Project for work claimed to have been done for, or materials claimed to have
been furnished to, shall be discharged or bonded by Tenant within twenty (20) days after the filing thereof, at Tenant’s sole cost and expense. 
 20.2. Should Tenant fail to discharge or bond against any lien of the nature described in Section 20.1, Landlord may, at Landlord’s election, pay such claim or post a bond or otherwise
provide security to eliminate the lien as a claim against title, and Tenant shall immediately reimburse Landlord for the costs thereof as Additional Rent. 
 20.3. In the event that Tenant leases or finances the acquisition of office, laboratory or manufacturing equipment, furnishings or other personal property of a removable nature utilized by Tenant in the
operation of Tenant’s business, Tenant warrants that any Uniform Commercial Code financing statement shall, upon its face or by exhibit thereto, indicate that such financing statement is applicable only to removable personal property of Tenant
located within the Premises. In no event shall the address of the Building be furnished on a financing statement without qualifying language as to applicability of the lien only to removable personal property located in an identified suite leased by
Tenant. Should any holder of a financing statement record or place of record a financing statement that appears to constitute a lien against any interest of Landlord or against equipment that may be located other than within an identified suite
leased by Tenant, Tenant shall, within ten (10) days after filing such financing statement, cause (a) a copy of the lender security agreement or other documents to which the financing statement pertains to be furnished to Landlord to
facilitate Landlord’s ability to demonstrate that the lien of such financing statement is not applicable to Landlord’s interest and (b) Tenant’s lender to amend such financing statement and any other documents of record to
clarify that any liens imposed thereby are not applicable to any interest of Landlord in the Premises or the Project. 
 21. Estoppel
Certificate. Tenant shall, within ten (10) days of receipt of written notice from Landlord, execute, acknowledge and deliver a statement in writing substantially in the form attached to this Lease as Exhibit I, or on any other form
reasonably requested by a proposed lender, mortgagee or beneficiary (each, a “Lender”) or purchaser, (a) certifying that this Lease is unmodified and in full force and effect (or, if modified, stating the nature of such
modification 

  
 19 

 
and certifying that this Lease as so modified is in full force and effect) and the dates to which rental and other charges are paid in advance, if any, (b) acknowledging that there are not,
to Tenant’s knowledge, any uncured defaults on the part of Landlord hereunder, or specifying such defaults if any are claimed, and (c) setting forth such further information with respect to this Lease or the Premises as may be requested
thereon. Any such statement may be relied upon by any prospective purchaser or encumbrancer of all or any portion of the real property of which the Premises are a part. Tenant’s failure to deliver such statement within such the prescribed time
shall, at Landlord’s option, constitute a Default (as defined below) under this Lease, and, in any event, shall be binding upon Tenant that the Lease is in full force and effect and without modification except as may be represented by Landlord
in any certificate prepared by Landlord and delivered to Tenant for execution. 
 21.1. Landlord shall, within ten
(10) days of receipt of written notice from Tenant, execute, acknowledge and deliver a statement in writing substantially in the form attached to this Lease as Exhibit J, or on any other form reasonably requested by a proposed lender,
mortgagee or beneficiary (each, a “Lender”) or purchaser, (a) certifying that this Lease is unmodified and in full force and effect (or, if modified, stating the nature of such modification and certifying that this Lease as so
modified is in full force and effect) and the dates to which rental and other charges are paid in advance, if any, (b) acknowledging that there are not, to Landlord’s knowledge, any uncured defaults on the part of Tenant hereunder, or
specifying such defaults if any are claimed, and (c) setting forth such further information with respect to this Lease or the Premises as may be requested thereon. Landlord’s failure to deliver such statement within such the prescribed
time shall be binding upon Landlord that the Lease is in full force and effect and without modification except as may be represented by Tenant in any certificate prepared by Tenant and delivered to Landlord for execution. 

22. Hazardous Materials. 

22.1. Tenant shall not cause or (during the Lease Term) permit any Hazardous Materials (as defined below) to be brought upon, kept or
used in or about the Premises or the Project in violation of Applicable Laws by Tenant, its agents, employees, contractors or invitees. If Tenant breaches such obligation, or if the presence of Hazardous Materials as a result of such a breach
results in contamination of the Premises or the Project or any adjacent property, or if contamination of the Premises or the Project or any adjacent property by Hazardous Materials otherwise occurs during the Term of this Lease or any extension or
renewal hereof or holding over hereunder, then Tenant shall indemnify, save, defend and hold Landlord, its agents and contractors harmless from and against any and all claims, judgments, damages, penalties, fines, costs, liabilities and losses
(including, without limitation, diminution in value of the Premises or the Project or any portion thereof; damages for the loss or restriction on use of rentable or usable space or of any amenity of the Premises or Project; damages arising from any
adverse impact on marketing of space in the Premises or the Project; and sums paid in settlement of claims, attorneys’ fees, consultants’ fees and experts’ fees) that arise during or after the Term as a result of such breach or
contamination. This indemnification of Landlord by Tenant includes, without limitation, costs incurred in connection with any investigation of site conditions or any cleanup, remedial, removal or restoration work required by any Governmental
Authority because of Hazardous Materials present in the air, soil or groundwater above, on or under the Premises during the Term or due to Tenant’s breach of this Lease. Without limiting the foregoing, if the presence of any Hazardous Materials
in, on, under or about the Premises or the Project or any adjacent property caused or permitted by Tenant results in any contamination of the Premises or the Project or any adjacent property, then Tenant shall promptly take all actions at its sole
cost and expense as are necessary to return the Premises or the Project and any adjacent property to their respective condition existing prior to the time of such contamination; provided that Landlord’s written approval of such action
shall first be obtained, which approval Landlord shall not unreasonably withhold; and provided, further, that it shall be reasonable for Landlord to withhold its consent if such actions could have a material adverse long-term or short-term
effect on the Premises or the Project. This Section 22.1 shall be subject to the terms of Article 44. 

22.2. Landlord acknowledges that it is not the intent of this Article 22 to prohibit Tenant from operating its business as
described in Section 2.7. Tenant may operate its business according to the custom of Tenant’s industry so long as the use or presence of Hazardous Materials is strictly and properly monitored according to Applicable Laws. As a
material 

  
 20 

 
inducement to Landlord to allow Tenant to use Hazardous Materials in connection with its business, Tenant agrees to deliver to Landlord prior to the Term Commencement Date a list identifying each
category of Hazardous Material to be present on the Premises and setting forth any and all governmental approvals or permits required in connection with the presence of such Hazardous Material on the Premises (the “Hazardous Materials
List”). Tenant’s current Hazardous Materials List is attached to this Lease as Exhibit G. Tenant shall deliver to Landlord an updated Hazardous Materials List on or prior to each annual anniversary of the Term Commencement Date
and shall deliver updated Hazardous Materials Lists to Landlord when required to give the same to any Governmental Authority. Tenant shall deliver to Landlord true and correct copies of the following documents (hereinafter referred to as the
“Documents”) relating to the handling, storage, disposal and emission of Hazardous Materials prior to the Term Commencement Date or, if unavailable at that time, concurrent with the receipt from or submission to any Governmental
Authority: permits; approvals; reports and correspondence; storage and management plans; notices of violations of Applicable Laws; plans relating to the installation of any storage tanks to be installed in or under the Premises or the Project
(provided that installation of storage tanks shall only be permitted after Landlord has given Tenant its written consent to do so, which consent Landlord may withhold in its sole and absolute discretion); and all closure plans or any other
documents required by any and all Governmental Authorities for any storage tanks installed in, on or under the Premises or the Project for the closure of any such storage tanks. Tenant shall not be required, however, to provide Landlord with any
portion of the Documents containing information of a proprietary nature that, in and of themselves, do not contain a reference to any Hazardous Materials or activities related to Hazardous Materials. Upon Landlord’s written request, Tenant
agrees that it shall enter into a written agreement with other tenants of the Project concerning the equitable allocation of fire control areas (as defined in the Uniform Building Code as adopted by the city or municipality(ies) in which the Project
is located (the “UBC”)) within the Project for the storage of Hazardous Materials. In the event that Tenant’s use of Hazardous Materials is such that it utilizes fire control areas in the Project in excess of Tenant’s Pro
Rata Share of the Project as set forth in Section 2.2, Tenant agrees that it shall, at its sole cost and expense and upon Landlord’s written request, establish and maintain a separate area of the Premises classified by the UBC as an
“H” occupancy area for the use and storage of Hazardous Materials or take such other action as is necessary to ensure that its share of the fire control areas of the Project is not greater than Tenant’s Pro Rata Share of the Project.

 22.3. Notwithstanding the provisions of Section 22.1, if Tenant or any transferee, assignee or sublessee is
subject to an enforcement order issued by any Governmental Authority in connection with the use, disposal or storage of Hazardous Materials at the Project and the condition triggering such enforcement order affects other tenant premises or
materially affects the Project (or any portion thereof) or the use thereof, then Landlord shall have the right to terminate this Lease in Landlord’s sole and absolute discretion (with respect to any such matter involving Tenant). Further if
Tenant or any proposed transferee, assignee or sublessee of Tenant has been required by any prior landlord, Lender or Governmental Authority to take remedial action in connection with Hazardous Materials contaminating a property as a result of such
party’s action or failure to act or use of the property in question, then Landlord may reasonably refuse to consent to a proposed transfer, assignment or sublease to such person. 

22.4. At any time, and from time to time, prior to the expiration of the Term, Landlord shall have the right to conduct appropriate tests
of the Premises or the Project to demonstrate that Hazardous Materials are present or that contamination has occurred due to Tenant or Tenant’s agents, employees or invitees. Tenant shall pay all reasonable costs of such tests of the Premises
if the tests disclose that Tenant has failed to comply with its obligations under this Article 22. 
 22.5. If
underground or other storage tanks storing Hazardous Materials are hereafter placed on the Premises by Tenant, Tenant shall monitor the storage tanks, maintain appropriate records, implement reporting procedures, properly close any underground
storage tanks, and take or cause to be taken all other steps necessary or required under the Applicable Laws. 
 22.6.
Tenant’s obligations under this Article 22 shall survive the expiration or earlier termination of the Lease. During any period of time needed by Tenant or Landlord after the termination of this Lease to complete the removal from the
Premises of any such Hazardous Materials, Tenant shall continue to pay Rent in accordance with this Lease, which Rent shall be 

  
 21 

 
prorated daily. Nothing in this Article 22, however, shall create any liability on the part of Tenant for any Hazardous Materials present at or about the Project prior to the Term
Commencement Date, which emanate onto the Project or Premises from outside the Project or Premises, or which were introduced to the Project or Premises by Landlord, its employees, contractors, agents or representatives, unless to the extent caused
by Tenant or its agents, employees or contractors. 
 22.7. As used herein, the term “Hazardous Material” means
any hazardous or toxic substance, material or waste that is or becomes regulated by any Governmental Authority. 
 22.8. To
Landlord’s knowledge, no Hazardous Materials exist at the Project in violation of Applicable Laws, other than as may be set forth in that certain Phase I Environmental Site Assessment by URS dated as of July 11, 2006, a copy of which has
been provided to Tenant. 
 23. Odors and Exhaust. 
 23.1. Tenant shall not cause or permit (or conduct any activities that would cause) any release of any odors or fumes of any kind from the Premises that are deemed offensive by a reasonable person.

 23.2. Provided Landlord maintains the Building’s Capacity with respect to the ventilation and electrical systems,
Tenant shall vent all fumes and odors from the Premises (and remove odors from Tenant’s exhaust stream) in compliance with Applicable Laws. The placement and configuration of all ventilation exhaust pipes, louvers and other equipment shall be
subject to Tenant’s and Landlord’s approval. 
 23.3. In the event that Landlord or Tenant receives complaints
regarding the release of such odors from the Premises, Tenant shall, at Tenant’s sole cost and expense, use commercially reasonable methods to provide odor eliminators and other devices (such as filters, air cleaners, scrubbers and whatever
other equipment may be necessary or appropriate from time to time) to abate such offensive odors, fumes or other substances in Tenant’s exhaust stream that emanate from the Premises. Any work Tenant performs under this paragraph shall
constitute Alterations. 
 24. Insurance; Waiver of Subrogation. 

24.1. Landlord shall maintain insurance for the Building and the Project in amounts equal to full replacement cost (exclusive of the
costs of excavation, foundations and footings, and without reference to depreciation taken by Landlord upon its books or tax returns) or such lesser coverage as Landlord may elect, provided that such coverage shall not be less than ninety
percent (90%) of such full replacement cost or the amount of such insurance Landlord’s Lender, if any, requires Landlord to maintain, providing protection against any peril generally included within the classification “Fire and
Extended Coverage,” together with insurance against sprinkler damage (if applicable), vandalism and malicious mischief. Landlord, subject to availability thereof, shall further insure, if Landlord deems it appropriate, coverage against flood,
environmental hazard, earthquake, loss or failure of building equipment, rental loss during the period of repairs or rebuilding, workmen’s compensation insurance and fidelity bonds for employees employed to perform services. Notwithstanding the
foregoing, Landlord may, but shall not be deemed required to, provide insurance for any improvements installed by Tenant or that are in addition to the standard improvements customarily furnished by Landlord, without regard to whether or not such
are made a part of or are affixed to the Building. 
 24.2. In addition, Landlord shall carry commercial liability insurance
with a single limit of not less than Three Million Dollars ($3,000,000), which, at Landlord’s discretion, may be provided through a combination of primary and umbrella coverage, for death or bodily injury, or property damage with respect to the
Project. 
 24.3. Tenant shall, at its own cost and expense, procure and maintain in effect, beginning on the Term Commencement
Date or the date of occupancy, whichever occurs first, and continuing throughout the Term (and occupancy by Tenant, if any, after termination of this Lease) commercial general liability insurance with limits of not less than Three Million Dollars
($3,000,000) per occurrence (which, at Tenant’s discretion, may be provided through a 

  
 22 

 
combination of primary and umbrella coverage) for death or bodily injury and for property damage with respect to the Premises (including $100,000 fire legal liability (each loss). 

24.4. The insurance required to be purchased and maintained by Tenant pursuant to this Lease shall name Landlord, BioMed Realty, L.P.,
BioMed Realty Trust, Inc., and their respective officers, employees, agents, general partners, members, subsidiaries, affiliates and Lenders (“Landlord Parties”) as additional insureds. Said insurance shall be with companies having
a rating of not less than policyholder rating of A and financial category rating of at least Class XII in “Best’s Insurance Guide.” Tenant shall obtain for Landlord from the insurance companies or cause the insurance companies to
furnish certificates of coverage to Landlord. No such policy shall be cancelable or subject to reduction of coverage or other modification or cancellation except after thirty (30) days’ prior written notice to Tenant from the insurer
(except in the event of non-payment of premium, in which case ten (10) days written notice shall be given) and Tenant shall prompt provide Landlord with a copy of any such notification. In addition, the insurer shall endeavor to provide thirty
(30) days’ prior written notice to Landlord of any reduction of coverage or other modification or cancellation of any such policy. All such policies shall be written as primary policies, not contributing with and not in excess of the
coverage that Landlord may carry. Tenant shall, at least twenty (20) days prior to the expiration of such policies, furnish Landlord with renewals or binders. Tenant agrees that if Tenant does not take out and maintain such insurance, Landlord
may (but shall not be required to) procure said insurance on Tenant’s behalf and at its cost to be paid by Tenant as Additional Rent. 
 24.5. Tenant assumes the risk of damage to any fixtures, goods, inventory, merchandise, equipment and leasehold improvements, and Landlord shall not be liable for injury to Tenant’s business or any
loss of income therefrom, relative to such damage, all as more particularly set forth within this Lease. Tenant shall, at Tenant’s sole cost and expense, carry such insurance as Tenant desires for Tenant’s protection with respect to
personal property of Tenant or business interruption. 
 24.6. In each instance where insurance is to name Landlord Parties as
additional insureds, Tenant shall, upon Landlord’s written request, also designate and furnish certificates evidencing such Landlord Parties as additional insureds to (a) any Lender of Landlord holding a security interest in the Building
or the Project, (b) the landlord under any lease whereunder Landlord is a tenant of the real property upon which the Building is located if the interest of Landlord is or shall become that of a tenant under a ground lease rather than that of a
fee owner, and (c) any management company retained by Landlord to manage the Project. 
 24.7. Notwithstanding anything to
the contrary set forth in this Lease, Landlord and Tenant each hereby waive any and all rights of recovery against the other or against the officers, directors, employees, agents and representatives of the other on account of loss or damage
occasioned by such waiving party or its property or the property of others under such waiving party’s control, in each case to the extent that such loss or damage is insured against under any fire and extended coverage insurance policy that
either Landlord or Tenant may have in force at the time of such loss or damage. Such waivers shall continue so long as their respective insurers so permit. Any termination of such a waiver shall be by written notice to the other party, containing a
description of the circumstances hereinafter set forth in this Section 24.7. Landlord and Tenant, upon obtaining the policies of insurance required or permitted under this Lease, shall give notice to the insurance carrier or carriers
that the foregoing mutual waiver of subrogation is contained in this Lease. If such policies shall not be obtainable with such waiver or shall be so obtainable only at a premium over that chargeable without such waiver, then the party seeking such
policy shall notify the other of such conditions, and the party so notified shall have ten (10) days thereafter to either (a) procure such insurance with companies reasonably satisfactory to the other party or (b) agree to pay such
additional premium (in Tenant’s case, in the proportion that the area of the Premises bears to the insured area). If the parties do not accomplish either (a) or (b), then this Section 24.7 shall have no effect during such time
as such policies shall not be obtainable or the party in whose favor a waiver of subrogation is desired refuses to pay the additional premium. If such policies shall at any time be unobtainable, but shall be subsequently obtainable, then neither
party shall be subsequently liable for a failure to obtain such insurance until a reasonable time after notification thereof by the other party. If the release of either Landlord or Tenant, as set forth in the first sentence of this
Section 24.7, shall contravene 

  
 23 

 
Applicable Laws, then the liability of the party in question shall be deemed not released but shall be secondary to the other party’s insurer. 

24.8. Landlord may require insurance policy limits required under this Lease to be raised to conform with reasonable requirements of any
Lenders of Landlord. 
 24.9. Any costs incurred by Landlord pursuant to this Article 24 (other than costs and claims
waived under Section 24.7 above) shall constitute a portion of Operating Expenses. 
 25. Damage or Destruction. 

25.1. In the event of a partial destruction of the Building or the Project by fire or other perils covered by extended coverage insurance
not exceeding twenty-five percent (25%) of the full insurable value thereof, and provided that (a) the damage thereto is such that the Building or the Project may be repaired, reconstructed or restored within a period of twelve
(12) months from the date of the happening of such casualty and (b) Landlord shall receive insurance proceeds sufficient to cover the cost of such repairs (except for any deductible amount provided by Landlord’s policy, which
deductible amount, if paid by Landlord, shall constitute an Operating Expense if the date of destruction is after the Term Commencement Date), Landlord shall commence and proceed diligently with the work of repair, reconstruction and restoration of
the Building or the Project, as applicable, and this Lease shall continue in full force and effect. 
 25.2. In the event of any
damage to or destruction of the Building or the Project other than as described in Section 25.1, Landlord may elect to repair, reconstruct and restore the Building or the Project, as applicable, in which case this Lease shall continue in
full force and effect. If Landlord elects not to repair the Building or the Project, as applicable, then this Lease shall terminate as of the date of such damage or destruction. In the event Landlord elects to terminate this Lease, Tenant shall have
the right within thirty (30) days of receipt of Landlord’s notice of termination to (a) notify Landlord that Tenant elects to repair the Premises (except the Building’s shell and core, which Landlord shall repair) and
(b) demonstrate to Landlord’s satisfaction that Tenant has (i) sufficient financial resources reasonably dedicated to pay its share of the cost of repair and (ii) the expertise and experience to ensure the repairs will occur in a
manner and result in Premises satisfactory to Landlord, in which event this Lease shall continue in full force and effect; provided, however, that (x) Tenant may only make such repairs if Tenant agrees to lease the entire Building for a
minimum of five (5) years following completion of such repairs, on terms mutually agreeable to Landlord and Tenant, (y) Tenant shall have no right to terminate the Lease thereafter related to such damage or destruction and
(z) Tenant’s right to make such repairs shall be subject to the rights of any Lender of Landlord. Tenant shall proceed to make such repairs in a manner reasonably acceptable to Landlord and at Tenant’s sole cost and expense, and
subject to such conditions as Landlord may reasonably impose, except that Landlord shall pay over and assign to Tenant all insurance proceeds with respect to such damage and restoration, subject to the rights of any Lenders of Landlord. 

25.3. Landlord shall give written notice to Tenant within sixty (60) days following the date of damage or destruction of the
estimated time to repair the Premises (“Repair Notice”) its election not to repair, reconstruct or restore the Building or the Project, as applicable. 
 25.4. Upon any termination of this Lease under any of the provisions of this Article 25, the parties shall be released thereby without further obligation to the other from the date possession of
the Premises is surrendered to Landlord, except with regard to (a) items occurring prior to the damage or destruction and (b) provisions of this Lease that, by their express terms, survive the expiration or earlier termination hereof.

 25.5. In the event of repair, reconstruction and restoration as provided in this Article 25, all Rent to be paid by
Tenant under this Lease shall be abated proportionately based on the extent to which Tenant’s use of the Premises is impaired during the period of such repair, reconstruction or restoration, unless Landlord provides Tenant with other space
during the period of repair that, in Tenant’s reasonable opinion, is suitable for the temporary conduct of Tenant’s business; provided, however, that the amount of such abatement shall be reduced by the proceeds of lost rental
income insurance actually received by Tenant with respect to the Premises. 

  
 24 

 25.6. Notwithstanding anything to the contrary contained in this Article 25, should
Landlord be delayed or prevented from completing the repair, reconstruction or restoration of the damage or destruction to the Premises after the occurrence of such damage or destruction by Force Majeure, then the time for Landlord to commence or
complete repairs shall be extended on a day-for-day basis; provided, however, that, at Landlord’s election, Landlord shall be relieved of its obligation to make such repair, reconstruction or restoration. 

25.7. If Landlord is obligated to or elects to repair, reconstruct or restore as herein provided, then Landlord shall be obligated to
make such repair, reconstruction or restoration only with regard to those portions of the Premises or the Project that were originally provided at Landlord’s expense (including the Tenant Improvements). After the Term Commencement Date, the
repair, reconstruction or restoration of improvements not originally provided by Landlord or at Landlord’s expense shall be the obligation of Tenant. In the event Tenant has elected to upgrade certain improvements from the Building Standard,
Landlord shall, upon the need for replacement due to an insured loss, provide only the Building Standard, unless Tenant again elects to upgrade such improvements and pay any incremental costs related thereto, except to the extent that excess
insurance proceeds, if received, are adequate to provide such upgrades, in addition to providing for basic repair, reconstruction and restoration of the Premises and the Project. 

25.8. Notwithstanding anything to the contrary contained in this Article 25, Landlord shall not have any obligation whatsoever to
repair, reconstruct or restore the Premises if the damage resulting from any casualty covered under this Article 25 occurs during the last twenty-four (24) months of the Term or any extension hereof, or to the extent that insurance
proceeds are not available therefor. 
 25.9. Landlord’s obligation, should it elect or be obligated to repair or rebuild,
shall be limited to the Property and the Building; provided that Tenant shall, at its expense, replace or fully repair all of Tenant’s personal property and any Alterations installed by Tenant existing at the time of such damage or
destruction. If the Property or the Building is to be repaired in accordance with the foregoing, Landlord shall make available to Tenant any portion of insurance proceeds it receives that are allocable to the Alterations constructed by Tenant
pursuant to this Lease; provided Tenant is not then in default (other than as a result of a change in control that constitutes a default under Section 30.1) under this Lease (and provided that, if Tenant cures such default
within the cure period (if any) permitted under this Lease, Landlord shall no longer be permitted to withhold such proceeds from Tenant), and subject to the requirements of any Lender of Landlord. 

25.10. Notwithstanding the foregoing, Tenant may terminate this Lease upon thirty (30) days’ prior written notice (which notice
shall be delivered to Landlord, if at all, no later than fifteen (15) days after Landlord delivers the Repair Notice to Tenant) if Landlord is required to or elects to perform such repair or restoration and either (a) the Repair Period
exceeds twelve (12) months (as the same may be extended due to a Tenant-caused delay or Force Majeure) or (b) the damage or destruction occurs within the last twelve (12) months of the Term. 

25.11. Notwithstanding anything to the contrary set forth in this Section 25, in the event of a casualty occurring prior to the Term
Commencement Date, (a) any costs or expenses incurred in connection with repairing any damage or restoring the Property and Premises as a result of such casualty shall not be included in TI Costs or Excess TI Costs and (b) Tenant shall not
have any responsibility to restore the Premises or Property. 
 26. Eminent Domain. 

26.1. In the event the whole of the Premises, or such part thereof as shall substantially interfere with Tenant’s use and occupancy
thereof, shall be taken for any public or quasi-public purpose by any lawful power or authority by exercise of the right of appropriation, condemnation or eminent domain, or sold to prevent such taking, Tenant or Landlord may terminate this Lease
effective as of the date possession is required to be surrendered to said authority. 
 26.2. In the event of a partial taking
of the Building or the Project, or of drives, walkways or parking areas serving the Building or the Project for any public or quasi-public purpose by any lawful power or authority by exercise of right of appropriation, condemnation, or

  
 25 

 
eminent domain, or sold to prevent such taking, then, without regard to whether any portion of the Premises occupied by Tenant was so taken, Landlord may elect to terminate this Lease as of such
taking if such taking is, in Landlord’s sole opinion, of a material nature such as to make it uneconomical to continue use of the unappropriated portion for purposes of renting office or laboratory space. 

26.3. Tenant shall be entitled to any award that is specifically awarded as compensation for (a) the taking of Tenant’s
personal property that was installed at Tenant’s expense and (b) the costs of Tenant moving to a new location. Except as set forth in the previous sentence, any award for such taking shall be the property of Landlord. 

26.4. If, upon any taking of the nature described in this Article 26, this Lease continues in effect, then Landlord shall promptly
proceed to restore the Premises and the Project, as applicable, to substantially their same condition prior to such partial taking. To the extent such restoration is feasible, as determined by Landlord in its reasonable discretion, the Rent shall be
decreased proportionately to reflect the loss of any portion of the Premises no longer available to Tenant. 
 26.5.
Notwithstanding anything to the contrary set forth in this Article 26, in the event of a taking (as described above) prior to the Term Commencement Date, (a) any costs or expenses incurred in connection with the Property and Premises as
a result of such taking shall not be included in TI Costs or Excess TI Costs and (b) Tenant shall not have any responsibility to restore the Premises or Property. 
 27. Surrender. 
 27.1. At least ten (10) days prior to Tenant’s
surrender of possession of any part of the Premises, Tenant shall provide Landlord with (a) a Phase I environmental assessment (“Phase I”) for the Premises and (b) written evidence of all appropriate governmental releases
obtained by Tenant in accordance with Applicable Laws, including, without limitation, laws pertaining to the surrender of the Premises. In addition, Tenant agrees to remain responsible after the surrender of the Premises for the remediation of any
recognized environmental conditions set forth in the Phase I for which Tenant is responsible hereunder and compliance with any recommendations set forth in the Phase I with respect to any conditions set forth in the Phase I for which Tenant is
responsible hereunder. Tenant’s obligations under this Section 27.1 shall survive the expiration or earlier termination of the Lease. 
 27.2. No surrender of possession of any part of the Premises shall release Tenant from any of its obligations hereunder, unless such surrender is accepted in writing by Landlord. 

27.3. The voluntary or other surrender of this Lease by Tenant shall not effect a merger with Landlord’s fee title or leasehold
interest in the Premises or the Property, unless Landlord consents in writing, and shall, at Landlord’s option, operate as an assignment to Landlord of any or all subleases. 

27.4. The voluntary or other surrender of any ground or other underlying lease that now exists or may hereafter be executed affecting the
Building or the Project, or a mutual cancellation thereof or of Landlord’s interest therein by Landlord and its lessor shall not effect a merger with Landlord’s fee title or leasehold interest in the Premises or the Property and shall, at
the option of the successor to Landlord’s interest in the Building or the Project, as applicable, operate as an assignment of this Lease. 

28. Holding Over. 

28.1. If, with Landlord’s prior written consent, Tenant holds possession of all or any part of the Premises after the Term, Tenant
shall become a tenant from month to month after the expiration or earlier termination of the Term, and in such case Tenant shall continue to pay (a) Base Rent in accordance with Article 8, as adjusted in accordance with Article 9,
and (b) any amounts for which Tenant would otherwise be liable under this Lease if the Lease were still in effect, including, without limitation, payments for Tenant’s Pro Rata Share of Operating Expenses. Any such month-to-month tenancy
shall be subject to every other term, covenant and agreement contained herein. 

  
 26 

 28.2. Notwithstanding the foregoing, if Tenant remains in possession of the Premises after
the expiration or earlier termination of the Term without Landlord’s prior written consent, Tenant shall become a tenant at sufferance subject to the terms and conditions of this Lease, except that the monthly rent shall be equal to one hundred
fifty percent (150%) of the Rent in effect during the last thirty (30) days of the Term. 
 28.3. Acceptance by
Landlord of Rent after the expiration or earlier termination of the Term shall not result in an extension, renewal or reinstatement of this Lease. 
 28.4. The foregoing provisions of this Article 28 are in addition to and do not affect Landlord’s right of reentry or any other rights of Landlord hereunder or as otherwise provided by
Applicable Laws. 
 29. Indemnification and Exculpation. 
 29.1. Tenant agrees to indemnify, save, defend and hold Landlord harmless from and against any and all demands, claims, liabilities, losses, costs, expenses, actions, causes of action, damages or
judgments, and all reasonable expenses (including, without limitation, reasonable attorneys’ fees, charges and disbursements) incurred in investigating or resisting the same (collectively, “Claims”) arising from injury or death
to any person or damage to any property occurring within or about the Premises or the Project arising directly or indirectly out of Tenant’s or Tenant’s employees’, agents’ or guests’ use or occupancy of the Premises or a
breach or default by Tenant in the performance of any of its obligations hereunder, except to the extent caused by Landlord’s willful misconduct or gross negligence. Notwithstanding the above, with respect to any Claims accruing prior to the
Term Commencement Date, Tenant’s indemnity obligation under this Lease shall be limited to Claims made by or against Landlord only, to the extent such Claims arise from (a) Exempt Causes, as defined in Section 44.3 below,
(b) the acts or failures to act of Tenant or any employee, contractor or agent of Tenant acting on behalf of Tenant and such acts or failures to act are not related to the construction of the Tenant Improvements, or (c) the acts or
failures to act of Tenant or any employee, contractor or agent of Tenant acting on behalf of Tenant and such acts or failures to act are related to the construction of the Tenant Improvements (provided, however, that in the case of any Claim
under this Subsection 29.1(c), the amounts recoverable from Tenant shall be limited as provided in Article 44 below). 
 29.2. Notwithstanding any provision of Section 29.1 to the contrary, Landlord shall not be liable to Tenant for, and Tenant assumes all risk of, damage to personal property or scientific
research, including, without limitation, loss of records kept by Tenant within the Premises and damage or losses caused by fire, electrical malfunction, gas explosion or water damage of any type (including, without limitation, broken water lines,
malfunctioning fire sprinkler systems, roof leaks or stoppages of lines), unless any such loss is due to Landlord’s willful disregard of written notice by Tenant of need for a repair that Landlord is responsible to make for an unreasonable
period of time. Tenant further waives any claim for injury to Tenant’s business or loss of income relating to any such damage or destruction of personal property as described in this Section 29.2. 

29.3. Landlord shall not be liable for any damages arising from any act, failure to act or neglect of any other tenant in the Project, or
of any other third party. 
 29.4. Tenant acknowledges that security devices and services, if any, while intended to deter
crime, may not in given instances prevent theft or other criminal acts. Landlord shall not be liable for injuries or losses caused by criminal acts of third parties, and Tenant assumes the risk that any security device or service may malfunction or
otherwise be circumvented by a criminal. If Tenant desires protection against such criminal acts, then Tenant shall, at Tenant’s sole cost and expense, obtain appropriate insurance coverage. 

29.5. The provisions of this Article 29 shall survive the expiration or earlier termination of this Lease. 

  
 27 

 30. Assignment or Subletting. 

30.1. Except as hereinafter expressly permitted, Tenant shall not, either voluntarily or by operation of Applicable Laws, directly or
indirectly sell, hypothecate, assign, pledge, encumber or otherwise transfer this Lease, or sublet the Premises (each, a “Transfer”), without Landlord’s prior written consent, which consent Landlord may not unreasonably
withhold, condition or delay. Tenant shall have the right to Transfer without Landlord’s prior written consent the Premises or any part hereof to any person that as of the date of determination directly, or indirectly through one or more
intermediaries, controls, is controlled by, or is under common control with Tenant (“Tenant’s Affiliate”), or any person or entity that acquires all or substantially all of Tenant’s assets or all the capital stock or other
ownership interest in Tenant; any entity with which Tenant merges, regardless of whether Tenant is the surviving entity; or any person or entity that acquires all or substantially all of the business or assets operated or located on the Premises
(“Successor”); provided that such Successor assumes in writing all of Tenant’s obligations under the Lease and the Successor at the time of such Transfer shall have no less than Twenty-Five Million Dollars ($25,000,000)
in cash or cash equivalent assets; and provided, further, that a Successor does not become a Successor for purposes of a sham or to evade the requirements of Applicable Laws or this Lease. Tenant shall notify Landlord in writing at least ten
(10) days prior to the effectiveness of such Transfer to Tenant’s Affiliate or Successor (an “Exempt Transfer”). In the event the disclosure of such Exempt Transfer would violate Applicable Laws or involve the disclosure
to Landlord of material non-public information (a “Confidentiality Issue”), then Tenant shall notify Landlord of such Exempt Transfer within two (2) business days following its consummation, Tenant shall otherwise comply with the
requirements of this Lease regarding such Exempt Transfer. For purposes of Exempt Transfers, “control” requires both (a) owning (directly or indirectly) more than fifty percent (50%) of the stock or other equity interests of
another person and (b) possessing, directly or indirectly, the power to direct or cause the direction of the management and policies of such person. 
 30.2. In the event Tenant desires to effect a Transfer other than an Exempt Transfer having a Confidentiality Issue, then, at least thirty (30) but not more than ninety (90) days prior to the
date when Tenant desires the assignment or sublease to be effective (the “Transfer Date”), Tenant shall provide written notice to Landlord (the “Transfer Notice”) containing information (including references)
concerning the character of the proposed transferee, assignee or sublessee; the Transfer Date; any ownership or commercial relationship between Tenant and the proposed transferee, assignee or sublessee; and the consideration and all other material
terms and conditions of the proposed Transfer, all in such detail as Landlord shall reasonably require. 
 30.3. Landlord, in
determining whether consent should be given to a proposed Transfer, may give consideration to (a) the financial strength of such transferee, assignee or sublessee (notwithstanding Tenant remaining liable for Tenant’s performance),
(b) any change in use that such transferee, assignee or sublessee proposes to make in the use of the Premises and (c) Landlord’s desire to exercise its rights under Section 30.8 to cancel this Lease. In no event shall
Landlord be deemed to be unreasonable for declining to consent to a Transfer to a transferee, assignee or sublessee of poor reputation, lacking financial qualifications or seeking a change in the Permitted Use, or jeopardizing directly or indirectly
the status of Landlord or any of Landlord’s affiliates as a Real Estate Investment Trust under the Internal Revenue Code of 1986 (as the same may be amended from time to time, the “Revenue Code”). Notwithstanding anything
contained in this Lease to the contrary, (w) no Transfer shall be consummated on any basis such that the rental or other amounts to be paid by the occupant, assignee, manager or other transferee thereunder would be based, in whole or in part,
on the income or profits derived by the business activities of such occupant, assignee, manager or other transferee; (x) Tenant shall not furnish or render any services to an occupant, assignee, manager or other transferee with respect to whom
transfer consideration is required to be paid, or manage or operate the Premises or any capital additions so transferred, with respect to which transfer consideration is being paid; (y) Tenant shall not consummate a Transfer with any person in
which Landlord owns an interest, directly or indirectly (by applying constructive ownership rules set forth in Section 856(d)(5) of the Revenue Code); and (z) Tenant shall not consummate a Transfer with any person or in any manner that
could cause any portion of the amounts received by Landlord pursuant to this Lease or any sublease, license or other arrangement for the right to use, occupy or possess any portion of the Premises to fail to qualify as “rents from real
property” within the meaning of Section 856(d) of the Revenue Code, or any similar or successor provision thereto or which could cause 

  
 28 

 
any other income of Landlord to fail to qualify as income described in Section 856(c)(2) of the Revenue Code. 
 30.4. As conditions precedent to Tenant subleasing the Premises or to Landlord considering a request by Tenant for Landlord’s consent to Tenant’s transfer of rights or sharing of the Premises,
Landlord may require any or all of the following: 
 (a) Tenant shall remain fully liable under this Lease during the unexpired
Term; 
 (b) Tenant shall provide Landlord with evidence reasonably satisfactory to Landlord that the value of Landlord’s
interest under this Lease shall not be diminished or reduced by the proposed Transfer. Such evidence shall include, without limitation, evidence respecting the relevant business experience and financial responsibility and status of the proposed
transferee, assignee or sublessee; 
 (c) Tenant shall reimburse Landlord for Landlord’s actual costs and expenses,
including, without limitation, reasonable attorneys’ fees, charges and disbursements incurred in connection with the review, processing and documentation of such request not to exceed Two Thousand Five Hundred Dollars ($2,500) per request;

 (d) Other than an Exempt Transfer, if Tenant’s transfer of rights or sharing of the Premises provides for the receipt
by, on behalf of or on account of Tenant of any consideration of any kind whatsoever (including, without limitation, a premium rental for a sublease or lump sum payment for an assignment, but excluding Tenant’s reasonable costs in marketing and
subleasing the Premises and improving the Premises in connection therewith) in excess of the rental and other charges due to Landlord under this Lease, Tenant shall pay fifty percent (50%) of all of such excess to Landlord, prior to deductions
for any transaction costs incurred by Tenant, including marketing expenses, tenant improvement allowances actually provided by Tenant, alterations, cash concessions, brokerage commissions, attorneys’ fees and free rent. If said consideration
consists of cash paid to Tenant, payment to Landlord shall be made upon receipt by Tenant of such cash payment; 
 (e) The
proposed transferee, assignee or sublessee shall agree that, in the event Landlord gives such proposed transferee, assignee or sublessee notice that Tenant is in default under this Lease, such proposed transferee, assignee or sublessee shall
thereafter make all payments otherwise due Tenant directly to Landlord, which payments shall be received by Landlord without any liability being incurred by Landlord, except to credit such payment against those due by Tenant under this Lease, and
any such proposed transferee, assignee or sublessee shall agree to attorn to Landlord or its successors and assigns should this Lease be terminated for any reason; provided, however, that in no event shall Landlord or its Lenders, successors
or assigns be obligated to accept such attornment; 
 (f) Landlord’s consent to any such Transfer shall be effected on
Landlord’s forms; 
 (g) Tenant shall not then be in default hereunder in any respect; 

(h) Such proposed transferee, assignee or sublessee’s use of the Premises shall be the same as the Permitted Use; 

(i) Landlord shall not be bound by any provision of any agreement pertaining to the Transfer, except for Landlord’s written consent
to the same; 
 (j) Tenant shall pay all transfer and other taxes (including interest and penalties) assessed or payable for any
Transfer; 
 (k) Landlord’s consent (or waiver of its rights) for any Transfer shall not waive Landlord’s right to
consent to any later Transfer; 
 (l) Tenant shall deliver to Landlord one executed copy of any and all written instruments
evidencing or relating to the Transfer; and 

  
 29 

 (m) A list of Hazardous Materials (as defined in Section 22.7), certified by the
proposed transferee, assignee or sublessee to be true and correct, that the proposed transferee, assignee or sublessee intends to use or store in the Premises. Additionally, Tenant shall deliver to Landlord, on or before the date any proposed
transferee, assignee or sublessee takes occupancy of the Premises, all of the items relating to Hazardous Materials of such proposed transferee, assignee or sublessee as described in Section 22.2. 

30.5. Any Transfer that is not in compliance with the provisions of this Article 30 shall be void and shall, at the option of
Landlord, terminate this Lease. 
 30.6. The consent by Landlord to a Transfer shall not relieve Tenant or proposed transferee,
assignee or sublessee from obtaining Landlord’s consent to any further Transfer, nor shall it release Tenant or any proposed transferee, assignee or sublessee of Tenant from full and primary liability under this Lease. 

30.7. Notwithstanding any Transfer, Tenant shall remain fully and primarily liable for the payment of all Rent and other sums due or to
become due hereunder, and for the full performance of all other terms, conditions and covenants to be kept and performed by Tenant. The acceptance of Rent or any other sum due hereunder, or the acceptance of performance of any other term, covenant
or condition thereof, from any person or entity other than Tenant shall not be deemed a waiver of any of the provisions of this Lease or a consent to any Transfer. 
 30.8. If Tenant delivers to Landlord a Transfer Notice indicating a desire to transfer this Lease to a proposed transferee, assignee or sublessee other than as provided within Section 30.4,
then Landlord shall have the option, exercisable by giving notice to Tenant at any time within ten (10) days after Landlord’s receipt of such Transfer Notice, to terminate this Lease as of the date specified in the Transfer Notice as the
Transfer Date, except for those provisions that, by their express terms, survive the expiration or earlier termination hereof. If Landlord exercises such option, then Tenant shall have the right to withdraw such Transfer Notice by delivering to
Landlord written notice of such election within five (5) days after Landlord’s delivery of notice electing to exercise Landlord’s option to terminate this Lease. In the event Tenant withdraws the Transfer Notice as provided in this
Section 30.8, this Lease shall continue in full force and effect. No failure of Landlord to exercise its option to terminate this Lease shall be deemed to be Landlord’s consent to a proposed Transfer. 

30.9. If Tenant sublets the Premises or any portion thereof, Tenant hereby immediately and irrevocably assigns to Landlord, as security
for Tenant’s obligations under this Lease, all rent from any such subletting, and appoints Landlord as assignee and attorney-in-fact for Tenant, and Landlord (or a receiver for Tenant appointed on Landlord’s application) may collect such
rent and apply it toward Tenant’s obligations under this Lease; provided that, until the occurrence of a Default (as defined below) by Tenant, Tenant shall have the right to collect such rent. 

30.10. Notwithstanding anything to the contrary herein, Tenant may not Transfer this Lease, including as part of an Exempt Transfer,
unless it concurrently Transfers the Office Lease to the same party in accordance with the terms of the Office Lease. 
 31. Subordination
and Attornment. 
 31.1. This Lease shall be subject and subordinate to the lien of any mortgage, deed of trust, or lease in
which Landlord is tenant now or hereafter in force against the Building or the Project and to all advances made or hereafter to be made upon the security thereof without the necessity of the execution and delivery of any further instruments on the
part of Tenant to effectuate such subordination. 
 31.2. Notwithstanding the foregoing, Tenant shall execute and deliver upon
demand such further instrument or instruments evidencing such subordination of this Lease to the lien of any such mortgage or mortgages or deeds of trust or lease in which Landlord is tenant as may be required by Landlord. If any such mortgagee,
beneficiary or landlord under a lease wherein Landlord is tenant (each, a “Mortgagee”) so elects, however, this Lease shall be deemed prior in lien to any such lease, mortgage, or deed of trust upon or including the Premises
regardless of date and Tenant shall execute a statement in writing to such effect at Landlord’s request. If Tenant fails to execute any document required from Tenant under this Section within ten (10)

  
 30 

 
days after written request therefor, Tenant hereby constitutes and appoints Landlord or its special attorney-in-fact to execute and deliver any such document or documents in the name of Tenant.
Such power is coupled with an interest and is irrevocable. Tenant’s obligations to subordinate its interest in this Lease are subject to Tenant’s receipt from any Mortgagee of a non-disturbance agreement on such Mortgagee’s typical
form. 
 31.3. Upon written request of Landlord and opportunity for Tenant to review, Tenant agrees to execute any Lease
amendments not materially altering the terms of this Lease, if required by a mortgagee or beneficiary of a deed of trust encumbering real property of which the Premises constitute a part incident to the financing of the real property of which the
Premises constitute a part. Any change affecting the amount or timing of the consideration to be paid by Tenant or modifying the Term of this Lease shall be deemed as materially altering the terms hereof. 

31.4. In the event any proceedings are brought for foreclosure, or in the event of the exercise of the power of sale under any mortgage
or deed of trust made by Landlord covering the Premises, Tenant shall at the election of the purchaser at such foreclosure or sale attorn to the purchaser upon any such foreclosure or sale and recognize such purchaser as Landlord under this Lease.

 32. Defaults and Remedies. 
 32.1. Late payment by Tenant to Landlord of Rent and other sums due shall cause Landlord to incur costs not contemplated by this Lease, the exact amount of which shall be extremely difficult and
impracticable to ascertain. Such costs include, but are not limited to, processing and accounting charges and late charges that may be imposed on Landlord by the terms of any mortgage or trust deed covering the Premises. Therefore, if any
installment of Rent due from Tenant is not received by Landlord within three (3) days after the date such payment is due, Tenant shall pay to Landlord an additional sum of six percent (6%) of the overdue Rent as a late charge. The parties
agree that this late charge represents a fair and reasonable estimate of the costs that Landlord shall incur by reason of late payment by Tenant. 
 32.2. No payment by Tenant or receipt by Landlord of a lesser amount than the Rent payment herein stipulated shall be deemed to be other than on account of the Rent, nor shall any endorsement or statement
on any check or any letter accompanying any check or payment as Rent be deemed an accord and satisfaction, and Landlord may accept such check or payment without prejudice to Landlord’s right to recover the balance of such Rent or pursue any
other remedy provided in this Lease or in equity or at law. If a dispute shall arise as to any amount or sum of money to be paid by Tenant to Landlord hereunder, Tenant shall have the right to make payment “under protest,” such payment
shall not be regarded as a voluntary payment, and there shall survive the right on the part of Tenant to institute suit for recovery of the payment paid under protest. 
 32.3. If Tenant fails to pay any sum of money required to be paid by it hereunder, or shall fail to perform any other act on its part to be performed hereunder, Landlord may, without waiving or releasing
Tenant from any obligations of Tenant, but shall not be obligated to, make such payment or perform such act; provided that such failure by Tenant continues for three (3) days after Landlord delivers notice to Tenant demanding performance
by Tenant; or provided that such failure by Tenant unreasonably interfered with the use of the Project by any other tenant or with the efficient operation of the Project, or resulted or could have resulted in a violation of Applicable Laws or the
cancellation of an insurance policy maintained by Landlord. Notwithstanding the foregoing, in the event of an emergency, Landlord shall have the right to enter the Premises and act in accordance with its rights as provided elsewhere in this Lease.
In addition to the late charge described in Section 32.1, Tenant shall pay to Landlord as Additional Rent all sums so paid or incurred by Landlord, together with interest thereon, from the date Tenant receives written notice that such
sums were paid or incurred, at the annual rate equal to twelve percent (12%) per annum or the highest rate permitted by Applicable Laws, whichever is less. 
 32.4. The occurrence of any one or more of the following events shall constitute a “Default” hereunder by Tenant: 

  
 31 

 (a) The abandonment of the Premises by Tenant; 

(b) The failure by Tenant to make any payment of Rent, as and when due, or to satisfy its obligations under Article 20, where such
failure shall continue for a period of three (3) days after written notice thereof from Landlord to Tenant; 
 (c) The failure
by Tenant to observe or perform any obligation or covenant contained herein (other than described in Subsections 32.4(a) and 32.4(b)) to be performed by Tenant, where such failure shall continue for a period of thirty (30) days
after written notice thereof from Landlord to Tenant; provided that, if the nature of Tenant’s default is such that it reasonably requires more than thirty (30) days to cure, Tenant shall not be deemed to be in Default if Tenant
shall commence such cure within said thirty (30) day period and thereafter diligently prosecute the same to completion; 

(d) Tenant makes an assignment for the benefit of creditors; 
 (e) A receiver, trustee or custodian is appointed to or does take title, possession or control of all or substantially all of Tenant’s assets; 

(f) Tenant files a voluntary petition under the United States Bankruptcy Code or any successor statute (as the same may be amended from
time to time, the “Bankruptcy Code”) or an order for relief is entered against Tenant pursuant to a voluntary or involuntary proceeding commenced under any chapter of the Bankruptcy Code; 

(g) Any involuntary petition if filed against Tenant under any chapter of the Bankruptcy Code and is not dismissed within one hundred
twenty (120) days; 
 (h) Failure to deliver an estoppel certificate in accordance with Article
21 within three (3) days after Tenant’s receipt of a second (2nd) request therefor; or 
 (i) Tenant’s interest in this Lease is
attached, executed upon or otherwise judicially seized and such action is not released within one hundred twenty (120) days of the action. 
 Notices given under this Section 32.4 shall specify the alleged default and shall demand that Tenant perform the provisions of this Lease or pay the Rent that is in arrears, as the case may
be, within the applicable period of time, or quit the Premises. No such notice shall be deemed a forfeiture or a termination of this Lease unless Landlord elects otherwise in such notice. 

32.5. In the event of a Default by Tenant, and at any time thereafter, with or without notice or demand and without limiting Landlord in
the exercise of any right or remedy that Landlord may have, Landlord shall be entitled to terminate Tenant’s right to possession of the Premises by any lawful means, in which case this Lease shall terminate and Tenant shall immediately
surrender possession of the Premises to Landlord. In such event, Landlord shall have the immediate right to re-enter and remove all persons and property, and such property may be removed and stored in a public warehouse or elsewhere at the cost and
for the account of Tenant, all without service of notice or resort to legal process and without being deemed guilty of trespass or becoming liable for any loss or damage that may be occasioned thereby. In the event that Landlord shall elect to so
terminate this Lease, then Landlord shall be entitled to recover from Tenant all damages incurred by Landlord by reason of Tenant’s default, including, without limitation: 

(a) The worth at the time of award of any unpaid Rent that had accrued at the time of such termination; plus 

(b) The worth at the time of award of the amount by which the unpaid Rent that would have accrued during the period commencing with
termination of the Lease and ending at the time of award exceeds that portion of the loss of Landlord’s rental income from the Premises that Tenant proves to Landlord’s reasonable satisfaction could have been reasonably avoided; plus

  
 32 

 (c) The worth at the time of award of the amount by which the unpaid Rent for the balance of
the Term after the time of award exceeds that portion of the loss of Landlord’s rental income from the Premises that Tenant proves to Landlord’s reasonable satisfaction could have been reasonably avoided; plus 

(d) Any other amount necessary to compensate Landlord for all the detriment caused by Tenant’s failure to perform its obligations
under this Lease or that in the ordinary course of things would be likely to result therefrom, including, without limitation, the cost of restoring the Premises to the condition required under the terms of this Lease; plus 

(e) At Landlord’s election, such other amounts in addition to or in lieu of the foregoing as may be permitted from time to time by
Applicable Laws. 
 As used in Subsections 32.5(a) and 32.5(b), “worth at the time of award” shall be computed by
allowing interest at the rate specified in Section 32.3. As used in Subsection 32.5(c), the “worth at the time of the award” shall be computed by taking the present value of such amount, using the discount rate of the
Federal Reserve Bank of San Francisco at the time of the award plus one (1) percentage point. 
 32.6. In addition to any
other remedies available to Landlord at law or in equity and under this Lease, Landlord shall have the remedy described in California Civil Code Section 1951.4 and may continue this Lease in effect after Tenant’s Default and abandonment
and recover Rent as it becomes due, provided Tenant has the right to sublet or assign, subject only to reasonable limitations). In addition, Landlord shall not be liable in any way whatsoever for its failure or refusal to relet the Premises.
For purposes of this Section 32.6, the following acts by Landlord will not constitute the termination of Tenant’s right to possession of the Premises: 
 (a) Acts of maintenance or preservation or efforts to relet the Premises, including, but not limited to, alterations, remodeling, redecorating, repairs, replacements or painting as Landlord shall consider
advisable for the purpose of reletting the Premises or any part thereof; or 
 (b) The appointment of a receiver upon the
initiative of Landlord to protect Landlord’s interest under this Lease or in the Premises. 
 Notwithstanding the foregoing, in the event
of a Default by Tenant, Landlord may elect at any time to terminate this Lease and to recover damages to which Landlord is entitled. 
 32.7. If Landlord does not elect to terminate this Lease as provided in Section 32.5, then Landlord may, from time to time, recover all Rent as it becomes due under this Lease. At any time
thereafter, Landlord may elect to terminate this Lease and to recover damages to which Landlord is entitled. 
 32.8. In the
event Landlord elects to terminate this Lease and relet the Premises, Landlord may execute any new lease in its own name. Tenant hereunder shall have no right or authority whatsoever to collect any Rent from such tenant. The proceeds of any such
reletting shall be applied as follows: 
 (a) First, to the payment of any indebtedness other than Rent due hereunder from
Tenant to Landlord, including, without limitation, storage charges or brokerage commissions owing from Tenant to Landlord as the result of such reletting; 
 (b) Second, to the payment of the costs and expenses of reletting the Premises, including (i) alterations and repairs that Landlord deems reasonably necessary and advisable and (ii) reasonable
attorneys’ fees, charges and disbursements incurred by Landlord in connection with the retaking of the Premises and such reletting; 
 (c) Third, to the payment of Rent and other charges due and unpaid hereunder; and 

(d) Fourth, to the payment of future Rent and other damages payable by Tenant under this Lease. 

  
 33 

 32.9. Notwithstanding anything to the contrary set forth herein, if the Default by Tenant
occurs prior to the Term Commencement Date, Tenant’s liability shall be limited as provided in Article 44 below. 

32.10. Notwithstanding anything to the contrary herein contained, or any other provisions of this Lease, if Landlord is exercising
remedies due solely to a Default arising from a Transfer of the Lease arising from a change of control of Tenant, any Tenant Affiliate or Successor that has not been approved by Landlord as required herein, and Tenant does not reasonably have any
control over such Transfer (“Limited Remedy Default”), then the aggregate amount Tenant shall be required to pay to Landlord from and after the date of the occurrence of such Limited Remedy Default (the “Occurrence
Date”) shall be limited to the sum of (a) the present value as of the Occurrence Date, discounted at the annual rate of twelve percent (12%) of all Rent for the unexpired portion of the Term from and after the Occurrence Date as
if this Lease had not been terminated, (b) any amounts of Additional Rent that are due and payable or have accrued under this Lease through the Occurrence Date, and (c) any amounts of Additional Rent that are due and payable or have
accrued under this Lease after the Occurrence Date while the Tenant remains in possession of the Premises after any Limited Remedy Default that relates to insurance, utilities, repairs, maintenance, environmental maintenance, remediation and
compliance and other routine and customary costs and expenses of operating and maintaining the Premises. Furthermore, additional reimbursement for any unpaid damages caused solely by a Limited Remedy Default may not be claimed by Landlord under any
other provision of this Lease or the Office Lease. In the event of a conflict between the provisions under this Section and any other provision of this Lease or the Office Lease, the provisions contained in this Section shall prevail. Nothing
contained in this Section shall limit any amounts payable by Tenant with respect to Base Rent or Additional Rent or any other amounts if any Default that is not a Limited Remedy Default has occurred. 

32.11. Except as provided in Sections 32.9 and 32.10 above, all of Landlord’s rights, options and remedies hereunder
shall be construed and held to be nonexclusive and cumulative. Landlord shall have the right to pursue any one or all of such remedies, or any other remedy or relief that may be provided by Applicable Laws, whether or not stated in this Lease. No
waiver of any default of Tenant hereunder shall be implied from any acceptance by Landlord of any Rent or other payments due hereunder or any failure by Landlord to take any action on account of such default if such default persists or is repeated,
and no express waiver shall affect defaults other than as specified in said waiver. 
 32.12. Landlord’s termination of
(a) this Lease or (b) Tenant’s right to possession of the Premises shall not relieve Tenant of any liability to Landlord that has previously accrued or that shall arise based upon events that occurred prior to the later to occur of
(i) the date of Lease termination or (ii) the date Tenant surrenders possession of the Premises. 
 32.13. To the
extent permitted by Applicable Laws, Tenant waives any and all rights of redemption granted by or under any present or future Applicable Laws if Tenant is evicted or dispossessed for any cause, or if Landlord obtains possession of the Premises due
to Tenant’s default hereunder or otherwise. 
 32.14. Landlord shall not be in default under this Lease unless Landlord
fails to perform obligations required of Landlord within a reasonable time, but in no event shall such failure continue for more than thirty (30) days after written notice from Tenant specifying the nature of Landlord’s failure;
provided, however, that if the nature of Landlord’s obligation is such that more than thirty (30) days are required for its performance, then Landlord shall not be in default if Landlord commences performance within such thirty
(30) day period and thereafter diligently prosecutes the same to completion. 
 32.15. In the event of any default by
Landlord, Tenant shall give notice by registered or certified mail to any (a) beneficiary of a deed of trust or (b) mortgagee under a mortgage covering the Premises or the Project and to any landlord of any lease of land upon or within
which the Premises or the Project is located, and shall allow such beneficiary, mortgagee or landlord a reasonable opportunity to cure the default, including time to obtain possession of the Premises by power of sale or a judicial action if such
should prove necessary to effect a cure; provided that 

  
 34 

 
Landlord shall have furnished to Tenant in writing the names and addresses of all such persons who are to receive such notices. 
 33. Bankruptcy. In the event a debtor, trustee or debtor in possession under the Bankruptcy Code, or another person with similar rights, duties and powers under any other Applicable Laws, proposes
to cure any default under this Lease or to assume or assign this Lease and is obliged to provide adequate assurance to Landlord that (a) a default shall be cured, (b) Landlord shall be compensated for its damages arising from any breach of
this Lease and (c) future performance of Tenant’s obligations under this Lease shall occur, then such adequate assurances shall include any or all of the following, as designated by Landlord in its sole and absolute discretion: 

33.1. Those acts specified in the Bankruptcy Code or other Applicable Laws as included within the meaning of “adequate
assurance,” even if this Lease does not concern a shopping center or other facility described in such Applicable Laws; 

33.2. A prompt cash payment to compensate Landlord for any monetary defaults or actual damages arising directly from a breach of this
Lease; 
 33.3. A cash deposit in an amount at least equal to the then-current amount of the Security Deposit; or 

33.4. The assumption or assignment of all of Tenant’s interest and obligations under this Lease. 

34. Brokers. 
 34.1.
Tenant represents and warrants that it has had no dealings with any real estate broker or agent in connection with the negotiation of this Lease other than Mark Pearson of CRESA Partners and Mark Daschbach of Cornish & Carey (collectively,
“Tenant’s Brokers”) and GVA Kidder Mathews and Cushman & Wakefield (collectively, “Landlord’s Brokers” and, collectively with Tenant’s Brokers, “Brokers”), and that it knows
of no other real estate broker or agent that is or might be entitled to a commission in connection with this Lease. Landlord shall compensate Brokers in relation to this Lease pursuant to separate agreements between Landlord and Brokers. 

34.2. Tenant represents and warrants that Tenant has not relied upon any representation or warranty made by any broker or agent in
Tenant’s decision to enter into this Lease, other than as contained in this Lease. 
 34.3. Tenant acknowledges and agrees
that the employment of brokers by Landlord is for the purpose of solicitation of offers of leases from prospective tenants and that no authority is granted to any broker to furnish any representation (written or oral) or warranty from Landlord
unless expressly contained within this Lease. Landlord is executing this Lease in reliance upon Tenant’s representations, warranties and agreements contained within Sections 34.1 and 34.2. 

34.4. Each party agrees to indemnify, defend and hold harmless the other from any and all cost or liability for compensation claimed by
any other broker or agent, other than Brokers, employed or engaged by the indemnifying party or claiming to have been employed or engaged by the indemnifying party. 
 35. Definition of Landlord. With regard to obligations imposed upon Landlord pursuant to this Lease, the term “Landlord,” as used in this Lease, shall refer only to Landlord or
Landlord’s then-current successor-in-interest. In the event of any transfer, assignment or conveyance of Landlord’s interest in this Lease or in Landlord’s fee title to or leasehold interest in the Property, as applicable, Landlord
herein named (and in case of any subsequent transfers or conveyances, the subsequent Landlord) shall be automatically freed and relieved, from and after the date of such transfer, assignment or conveyance, from all liability for the performance of
any covenants or obligations contained in this Lease thereafter to be performed by Landlord and, without further agreement, the transferee, assignee or conveyee of Landlord’s in this Lease or in Landlord’s fee title to or leasehold
interest in the Property, as applicable, shall be deemed to have assumed and agreed to observe and perform any and all covenants and obligations of Landlord hereunder 

  
 35 

 
during the tenure of its interest in the Lease or the Property. Landlord or any subsequent Landlord may transfer its interest in the Premises or this Lease without Tenant’s consent.

 36. Limitation of Landlord’s Liability. 
 36.1. If Landlord is in default under this Lease and, as a consequence, Tenant recovers a monetary judgment against Landlord, the judgment shall be satisfied only out of (a) the proceeds of sale
received on execution of the judgment and levy against the right, title and interest of Landlord in the Project of which the Premises are a part, (b) rent or other income from such real property receivable by Landlord or (c) the
consideration received by Landlord from the sale, financing, refinancing or other disposition of all or any part of Landlord’s right, title or interest in the Project of which the Premises are a part. 

36.2. Landlord shall not be personally liable for any deficiency under this Lease. If Landlord is a partnership or joint venture, then
the partners of such partnership shall not be personally liable for Landlord’s obligations under this Lease, and no partner of Landlord shall be sued or named as a party in any suit or action, and service of process shall not be made against
any partner of Landlord except as may be necessary to secure jurisdiction of the partnership or joint venture. If Landlord is a corporation, then the shareholders, directors, officers, employees and agents of such corporation shall not be personally
liable for Landlord’s obligations under this Lease, and no shareholder, director, officer, employee or agent of Landlord shall be sued or named as a party in any suit or action, and service of process shall not be made against any shareholder,
director, officer, employee or agent of Landlord. If Landlord is a limited liability company, then the members of such limited liability company shall not be personally liable for Landlord’s obligations under this Lease, and no member of
Landlord shall be sued or named as a party in any suit or action, and service of process shall not be made against any member of Landlord except as may be necessary to secure jurisdiction of the limited liability company. No partner, shareholder,
director, employee, member or agent of Landlord shall be required to answer or otherwise plead to any service of process, and no judgment shall be taken or writ of execution levied against any partner, shareholder, director, employee or agent of
Landlord. 
 36.3. Each of the covenants and agreements of this Article 36 shall be applicable to any covenant or
agreement either expressly contained in this Lease or imposed by Applicable Laws and shall survive the expiration or earlier termination of this Lease. 
 37. Joint and Several Obligations. If more than one person or entity executes this Lease as Tenant, then: 
 37.1. Each of them is jointly and severally liable for the keeping, observing and performing of all of the terms, covenants, conditions, provisions and agreements of this Lease to be kept, observed or
performed by Tenant; and 
 37.2. The term “Tenant,” as used in this Lease shall mean and include each of them,
jointly and severally. The act of, notice from, notice to, refund to, or signature of any one or more of them with respect to the tenancy under this Lease, including, without limitation, any renewal, extension, expiration, termination or
modification of this Lease, shall be binding upon each and all of the persons executing this Lease as Tenant with the same force and effect as if each and all of them had so acted, so given or received such notice or refund, or so signed.

 38. Authority. Tenant covenants, warrants and represents that (a) Tenant is duly incorporated or otherwise established or formed
and validly existing under the laws of its state of incorporation, establishment or formation, (b) Tenant has and is duly qualified to do business in the state in which the Property is located, (c) Tenant has full corporate, partnership,
trust, association or other appropriate power and authority to enter into this Lease and to perform all Tenant’s obligations hereunder and (d) each person (and all of the persons if more than one signs) signing this Lease on behalf of
Tenant is duly and validly authorized to do so. 
 39. Confidentiality. Tenant shall not disclose any terms or conditions of this Lease
(including Rent) or give a copy of this Lease to any third party, and Landlord shall not release to any third party any nonpublic financial information or nonpublic information about Tenant’s ownership structure that Tenant gives Landlord,
except (a) if required by Applicable Laws or in any judicial proceeding; provided that the releasing party has given the other party reasonable notice of such 

  
 36 

 
requirement, if feasible, (b) to a party’s attorneys, accountants, brokers, lenders, investors and other bona fide consultants or advisers and potential purchasers; provided such
third parties agree to be bound by this paragraph or (c) to bona fide prospective assignees or subtenants of this Lease; provided they agree in writing to be bound by this paragraph. 

40. Notices. Any notice, consent, demand, bill, statement or other communication required or permitted to be given hereunder shall be in writing
and shall be given by personal delivery, overnight delivery with a reputable nationwide overnight delivery service, or certified mail (return receipt requested), and if given by personal delivery, shall be deemed delivered upon receipt; if given by
overnight delivery, shall be deemed delivered one (1) day after deposit with a reputable nationwide overnight delivery service; and, if given by certified mail (return receipt requested), shall be deemed delivered three (3) business days
after the time the notifying party deposits the notice with the United States Postal Service. Any notices given pursuant to this Lease shall be addressed to Tenant at the Premises, or to Landlord or Tenant at the addresses shown in Sections
2.9 and 2.10, respectively. Either party may, by notice to the other given pursuant to this Section, specify additional or different addresses for notice purposes. 
 41. Miscellaneous. 
 41.1. Landlord reserves the right to change the name
of the Project or the Building in its sole discretion. 
 41.2. To induce Landlord to enter into this Lease, Tenant agrees that
it shall promptly furnish to Landlord, from time to time, upon Landlord’s written request, the most recent unaudited (or, if available, audited) year-end financial statements reflecting Tenant’s current financial condition. Tenant shall,
within ninety (90) days after the end of Tenant’s financial year, furnish Landlord with a certified copy of Tenant’s unaudited (or, if available, audited) year-end financial statements for the previous year. Tenant represents and
warrants that all financial statements, records and information furnished by Tenant to Landlord in connection with this Lease are true, correct and complete in all material respects. 

41.3. Where applicable in this Lease, the singular includes the plural and the masculine or neuter includes the masculine, feminine and
neuter. The section headings of this Lease are not a part of this Lease and shall have no effect upon the construction or interpretation of any part hereof. 
 41.4. If either party commences an action against the other party arising out of or in connection with this Lease, then the substantially prevailing party shall be entitled to have and recover from the
other party reasonable attorneys’ fees, charges and disbursements and costs of suit. 
 41.5. Submission of this instrument
for examination or signature by Tenant does not constitute a reservation of or option for a lease, and shall not be effective as a lease or otherwise until execution by and delivery to both Landlord and Tenant. 

41.6. Time is of the essence with respect to the performance of every provision of this Lease in which time of performance is a factor.

 41.7. Each provision of this Lease performable by Tenant shall be deemed both a covenant and a condition. 

41.8. Whenever consent or approval of either party is required, that party shall not unreasonably withhold such consent or approval,
except as may be expressly set forth to the contrary. 
 41.9. The terms of this Lease are intended by the parties as a final
expression of their agreement with respect to the terms as are included herein, and may not be contradicted by evidence of any prior or contemporaneous agreement. 
 41.10. Any provision of this Lease that shall prove to be invalid, void or illegal shall in no way affect, impair or invalidate any other provision hereof, and all other provisions of this 

  
 37 

 
Lease shall remain in full force and effect and shall be interpreted as if the invalid, void or illegal provision did not exist. 

41.11. Landlord may, but shall not be obligated to, record a short form or memorandum hereof without Tenant’s consent. Neither party
shall record this Lease. 
 41.12. The language in all parts of this Lease shall be in all cases construed as a whole according
to its fair meaning and not strictly for or against either Landlord or Tenant. 
 41.13. Each of the covenants, conditions and
agreements herein contained shall inure to the benefit of and shall apply to and be binding upon the parties hereto and their respective heirs; legatees; devisees; executors; administrators; and permitted successors, assigns, sublessees. Nothing in
this Section 41.13 shall in any way alter the provisions of this Lease restricting assignment or subletting. 

41.14. This Lease shall be governed by, construed and enforced in accordance with the laws of the State in which the Premises are
located, without regard to such State’s conflict of law principles. 
 41.15. This Lease may be executed in one or more
counterparts, each of which, when taken together, shall constitute one and the same document. 
 41.16. No provision of this
Lease may be modified, amended or supplemented except by an agreement in writing signed by Landlord and Tenant. The waiver by Landlord of any breach by Tenant of any term, covenant or condition herein contained shall not be deemed to be a waiver of
any subsequent breach of the same or any other term, covenant or condition herein contained. 
 41.17. The parties waive trial
by jury in any action, proceeding or counterclaim brought by the other party hereto related to matters arising out of or in any way connected with this Lease; the relationship between Landlord and Tenant; Tenant’s use or occupancy of the
Premises; or any claim of injury or damage related to this Lease or the Premises. 
 42. Options to Extend Term. Tenant shall have two
(2) options (each, an “Option”) to extend the Term of this Lease by seven (7) years each as to the entire Premises (and no less than the entire Premises) upon the following terms and conditions. Any extension of the Term
pursuant to an Option shall be on all the same terms and conditions as this Lease, except as follows: 
 42.1. No Option is
assignable separate and apart from this Lease. 
 42.2. An Option is conditional upon Tenant giving Landlord written notice of
its election to exercise such Option at least twelve (12) months prior to the end of the expiration of the then-current Term of this Lease. Time shall be of the essence as to Tenant’s exercise of an Option. Tenant assumes full
responsibility for maintaining a record of the deadlines to exercise an Option. Tenant acknowledges that it would be inequitable to require Landlord to accept any exercise of an Option after the date provided for in this paragraph. 

42.3. Base Rent during each Option term shall equal ninety-five percent (95%) of the fair market rent as of the commencement of such
Option term, including fair market rent increases (“FMR”). If Landlord and Tenant cannot agree on the FMR for an Option term within thirty (30) days after the date on which Tenant notifies Landlord that it is exercising an
Option, then, no later than an additional thirty (30) days thereafter (the “Submission Period”), Landlord and Tenant shall each furnish to the other a notice in writing (a “FMR Notice”) stating such
party’s estimate of the FMR. Such notices shall be accompanied by a statement from a qualified, licensed real estate appraiser with at least ten (10) years’ experience in the Fremont/Newark area (an “Appraiser”)
stating such Appraiser’s opinion of FMR. If, within twenty (20) days after expiration of the Submission Period, Landlord and Tenant still cannot agree on the FMR, the two (2) Appraisers shall appoint a third qualified, licensed real estate
appraiser (the “Referee”) within seven (7) days thereafter. If the Appraisers are unable to agree upon the selection of the Referee, then the Referee shall be selected within ten (10) days thereafter from among the
Northern California panel of qualified Real Estate Industry Arbitrators of the American Arbitrator Association (the “Association”) pursuant to the Real Estate Industry Arbitration rules of the Association. The Referee shall, within
thirty (30) days after appointment, render the Referee’s 

  
 38 

 
decision as to the FMR, which opinion shall be strictly limited to choosing one of the two determinations made by the Appraisers. The decision by the Referee shall be binding upon Landlord and
Tenant, and each shall pay for its own appraisal. The cost of the Referee shall be shared equally by Landlord and Tenant. In determining FMR, Landlord, Tenant and, if applicable, the Appraisers and Referee shall each take into account all relevant
factors, including, without limitation, (i) the size of the Premises and length of the Option term, (ii) Tenant’s creditworthiness, (iii) rent in comparable buildings in the relevant competitive market, including concessions
offered to new tenants, such as free rent, tenant improvement allowances, and moving allowances, and (iv) the quality and location of the Premises and the Project. 
 42.4. Notwithstanding anything contained in this Article 42, Tenant shall not have the right to exercise an Option: 
 (a) During the time commencing from the date Landlord delivers to Tenant a written notice that Tenant is in default under any provisions of this Lease and continuing until Tenant has cured the specified
default to Landlord’s reasonable satisfaction; or 
 (b) At any time after any Default as described in Article 32 of
the Lease (provided, however, that, for purposes of this Subsection 42.4(b), Landlord shall not be required to provide Tenant with notice of such Default) and continuing until Tenant cures any such Default, if such Default is
susceptible to being cured; or 
 (c) In the event that Tenant has defaulted in the performance of its obligations under this
Lease two (2) or more times and a service or late charge has become payable under Section 32.1 for each of such defaults during the twelve (12)-month period immediately prior to the date that Tenant intends to exercise an Option,
whether or not Tenant has cured such defaults. 
 42.5. The period of time within which Tenant may exercise an Option shall not
be extended or enlarged by reason of Tenant’s inability to exercise such Option because of the provisions of Section 42.4. 
 42.6. All of Tenant’s rights under the provisions of an Option shall terminate and be of no further force or effect even after Tenant’s due and timely exercise of such Option if, after such
exercise, but prior to the commencement date of the new term, (a) Tenant fails to pay to Landlord a monetary obligation of Tenant for a period of twenty (20) days after written notice from Landlord to Tenant, (b) Tenant fails to
commence to cure a default (other than a monetary default) within thirty (30) days after the date Landlord gives notice to Tenant of such default or (c) Tenant has defaulted under this Lease two (2) or more times and a service or late
charge under Section 32.1 has become payable for any such default, whether or not Tenant has cured such defaults. 
 43. Right of
First Refusal. Subject to the rights of Risk Management Solutions, Inc., and its successors and assigns, and (with respect to the portion of Building No. 1 depicted on Exhibit M attached hereto) any other tenants that enter into
leases for Building No. 1 within six (6) months after the Execution Date (the “Prior Rights”), and for so long as Tenant has not assigned the Lease (other than as part of an Exempt Transfer) and is not then subleasing more
than twenty-five percent (25%) of the Premises, Tenant shall have a right of first refusal (“ROFR”) as to any rentable premises in Building No. 1 and/or Building No. 3 for which Landlord is seeking a tenant
(“Available ROFR Premises”) and for which Landlord receives a bona fide offer from a third party (an “Offer”); provided, however, that in no event shall Landlord be required to lease any Available ROFR
Premises to Tenant for any period past the date on which this Lease expires or is terminated pursuant to its terms. To the extent that Landlord renews or extends a then-existing lease with any then-existing tenant of any space, or enters into a new
lease with such then-existing tenant, the affected space shall not be deemed to be Available ROFR Premises. In the event Landlord receives an Offer, Landlord shall provide written notice thereof to Tenant (the “Notice of Offer”).

 43.1. Within five (5) business days following its receipt of a Notice of Offer, Tenant shall advise Landlord in writing
whether Tenant elects to lease all (not just a portion) of the Available ROFR Premises on the terms and conditions set forth in the Notice of Offer. If Tenant fails to notify Landlord of Tenant’s election within said five (5) business day
period, then Tenant shall be deemed to have elected not to lease the Available ROFR Premises. 

  
 39 

 43.2. If Tenant timely notifies Landlord that Tenant elects to lease the Available ROFR
Premises on the terms and conditions set forth in the Notice of Offer, then Landlord shall lease the Available ROFR Premises to Tenant upon the terms and conditions set forth in the Notice of Offer. 

43.3. If Tenant notifies Landlord that Tenant elects not to lease the Available ROFR Premises on the terms and conditions set forth in
the Notice of Offer, or if Tenant fails to notify Landlord of Tenant’s election within the five (5) business day period described above, then Landlord shall have the right to consummate the lease of the Available ROFR Premises on the same
terms as set forth in the Notice of Offer within one hundred eighty (180) days following Tenant’s election (or deemed election) not to lease the Available ROFR Premises. If Landlord does not lease the Available ROFR Premises within said
one hundred eighty (180)-day period on such terms or materially comparable terms, then the ROFR shall be fully reinstated, and Landlord shall not thereafter lease the Available ROFR Premises without first complying with the procedures set forth in
this Article 43. 
 43.4. Notwithstanding anything in this Article 43 to the contrary, Tenant shall not exercise
the ROFR during such period of time that Tenant is in default under any provision of this Lease. Any attempted exercise of the ROFR during a period of time in which Tenant is so in default shall be void and of no effect. In addition, Tenant shall
not be entitled to exercise the ROFR if Landlord has given Tenant two (2) or more notices of default under this Lease, whether or not the defaults are cured, during the twelve (12) month period prior to the date on which Tenant seeks to
exercise the ROFR. 
 43.5. Other than in connection with an Exempt Transfer, Tenant shall not assign or transfer the ROFR,
either separately or in conjunction with an assignment or transfer of Tenant’s interest in the Lease, without Landlord’s prior written consent, which consent Landlord may withhold in its sole and absolute discretion. 

44. Liability of Tenant. Notwithstanding anything to the contrary set forth in this Lease, except for any damages, claims and liabilities arising
directly from Exempt Causes (as defined below), in no event shall Tenant’s liability for obligations payable or accruing under this Lease prior to the Term Commencement Date, including without limitation any Rent, indemnification and hold
harmless obligations, or any damages for any breach occurring prior to the Term Commencement Date, exceed (a) eighty-nine and ninety-five hundredths percent (89.95%) of the then-incurred construction costs for the Property that are
properly capitalizable under generally accepted accounting principles as of such date (after having decreased such costs for any Force Majeure Costs (as defined below) and for the remediation of any Force Majeure Event) minus the sum of any payments
previously paid to Landlord by Tenant toward such construction costs that have been future valued at twelve percent (12%) to such point in time plus (b) the present value of any future payments made by Tenant towards such construction
costs discounted at twelve percent (12%) that Tenant is obligated to make to Landlord, but in each case excluding payments that are not required to be included in the calculation of the Tenant’s maximum guaranty amount under EITF 97-10.

 44.1. “Force Majeure Costs” means the sum of (a) all costs and expenses that are incurred by Landlord
to restore the Premises in connection with a Force Majeure Event (as defined below), including (i) all capitalized interest and other collateral costs and carrying costs accruing on such costs and expenses necessary to repair and restore damage
caused by such Force Majeure Event following such Force Majeure Event and (ii) all capitalized interest and other collateral costs and carrying costs accruing as a result of time delays necessary to repair and restore damage caused by such
Force Majeure Event following such Force Majeure Event) less the amount of all insurance proceeds applied to the restoration of the Premises and (b) to the extent the Premises is not restored following such Force Majeure Event, the reduction,
if any, in the fair market value of the Premises as a result of such Force Majeure Event, as set forth in an appraisal in form and substance reasonably satisfactory to Landlord conducted by an independent appraiser selected by Landlord;
provided, however, that in no event shall the amount determined in the foregoing clause (b) be less than the remaining estimated cost to restore the Premises to substantially the same condition as immediately prior to the Force Majeure
Event. 

  
 40 

 44.2. “Force Majeure Event” shall mean the occurrence of one or more events
that causes damage to the Premises or any portion thereof caused by Landlord or Landlord’s employees, agents, contractors or subcontractors, acts of God (including fire, floods, tornadoes or hurricanes) or any other cause, unless such damage is
caused by Tenant or its agents, employees or contractors. 
 44.3. “Exempt Causes” means (a) any
misapplication of funds, fraud, willful misconduct or illegal acts and (b) Tenant’s filing of a voluntary petition under the Bankruptcy Code or an order for relief being entered against Tenant pursuant to a voluntary or an involuntary
proceeding being commenced under any chapter of the Bankruptcy Code. 
 [REMAINDER OF THIS PAGE INTENTIONALLY LEFT BLANK]

  
 41 

 IN WITNESS WHEREOF, the parties hereto have executed this Lease as of the date first above
written. 
  

			
	LANDLORD:
	
	 BMR-GATEWAY BOULEVARD LLC,
 a Delaware limited liability company

		
	By:	 	 /s/ John F. Wilson, II

	Name:	 	 John F. Wilson, II

	Title:	 	 Executive V.P.

	
	TENANT:
	
	 REVANCE THERAPEUTICS, INC.,
 a Delaware corporation

		
	By:	 	 /s/ L. Daniel Browne

	Name:	 	 L. Daniel Browne

	Title:	 	 President / CEO

 EXHIBIT A 
 PREMISES 
  
 

 

  
 A-1

  
 

 

 EXHIBIT B 
 WORK LETTER 
 This Work Letter (the
“Work Letter”) is made and entered into as of the 31st day of March, 2008, by and between BMR-GATEWAY BOULEVARD LLC, a Delaware limited liability company (“Landlord”), and REVANCE THERAPEUTICS, INC., a Delaware corporation
(“Tenant”), and is attached to and made a part of that certain Lease dated as of March 31, 2008 (the “Lease”), by and between Landlord and Tenant for the Premises located at 7555 Gateway Boulevard in Newark,
California. This Work Letter describes the process pursuant to which Landlord shall cause the Tenant Improvements to be constructed. All capitalized terms used but not otherwise defined herein shall have the meanings given them in the Lease.

 1. General Requirements. 
 1.1. Tenant’s Authorized Representatives. Tenant designates (a) L. Daniel Browne and (b) Sharron Reiss-Miller of SRM Consulting Services, LLC (“Tenant’s Authorized
Representatives”), as the persons authorized to approve and initial all plans, drawings, changes orders and approvals pursuant to this Work Letter. Landlord shall not be obligated to respond to or act upon any such item until such item has
been initialed by either one or both of Tenant’s Authorized Representatives. Sharron Reiss-Miller may attend design meetings as deemed necessary by Tenant. 
 1.2. Landlord’s Authorized Signatory and Project Manager. Landlord designates Chuck Flynn as Landlord’s project manager in connection with managing construction of the Tenant Improvements
(“Landlord’s Project Manager”). Landlord’s third party construction manager (“Third Party Manager”) shall be Matrix Construction Management, Inc. Landlord may change Landlord’s Project Manager or
Third Party Manager from time to time upon prior written notice to Tenant, subject to Tenant’s approval, which approval shall not be unreasonably withheld, conditioned or delayed. 

1.3. Tenant Improvements Schedule. The schedule for the design and development of Tenant Improvements, including, without
limitation, the time periods for preparation and review of construction documents, approvals and performance, shall be in accordance with a schedule prepared by Landlord and Tenant (the “Schedule”). The current Schedule is attached
as Attachment 1 hereto, although Landlord and Tenant acknowledge and agree that the Schedule shall be updated to reflect a start date of April 14, 2008, and the remaining items on the Schedule adjusted accordingly. The Schedule shall be
subject to adjustment as mutually agreed upon in writing by the parties, or as provided in this Work Letter. 
 1.4.
Architects and Consultants. The general contractor, architect, engineering consultants, and major subcontractors responsible for the construction of the Tenant Improvements (“Subject Vendors”) shall be retained by Landlord
and approved by Tenant, which approval Tenant shall not unreasonably withhold, condition or delay. Landlord and Tenant hereby approve of the following vendors (vendors approved in writing by Tenant are referred to herein individually as a
“Tenant Approved Vendor” and collectively as “Tenant Approved Vendors”). 
 (a) XL
Construction Corporation (such entity, or its replacement in accordance with the terms of this Work Letter, “Contractor”) as the general contractor. 
 (b) DGA planning | architecture | interiors (such entity, or its replacement in accordance with the terms of this Work Letter, “Architect”) as the architect; 

(c) Affiliated Engineers, Inc. (such entity, or its replacement in accordance with the terms of this Work Letter, “MEP
Engineer”) as the MEP engineer. The MEP’s current scope of work is attached as Attachment 2 to this Work Letter; 
 (d) CRB Consulting Engineers and Andrew Malcolm Consulting (collectively, such entities or their replacements in accordance with the terms of this Work Letter, “Process Engineers”) as the
process engineers; and 
 (e) ACME Security as the security system vendor. 

  
 B-1

 In the event that Landlord deems it reasonably necessary to replace a Subject Vendor, Tenant shall have the
right to approve such replacement within five (5) days after written notice from Landlord, which approval Tenant shall not unreasonably withhold, condition or delay. The structural engineer’s current scope of work is attached as
Attachment 3 to this Work Letter 
 2. Tenant Improvements. 

2.1. Budget. Landlord shall coordinate the completion of cost analysis/budget estimates at each significant phase (establishment
of Draft Plans Design Development Plans, Permit Set Plans and Final Plans) (each, a “Budget”), and shall submit the estimates to Tenant for Tenant’s approval, which approval Tenant shall not unreasonably withhold, condition or
delay. Tenant shall have five (5) business days to approve or disapprove each proposed Budget, and failure to respond within such time shall be deemed approval by Tenant. If a Budget is disapproved by Tenant, then Tenant shall at the time of
such disapproval notify Landlord in writing of its objections to such Budget and the parties shall confer and negotiate in good faith to reach agreement on the Budget, including, without limitation, by agreeing to request redesign efforts by
Architect, MEP Engineer or Process Engineers, as applicable, to reduce the Budget to an amount reasonably acceptable to Tenant. A conceptual budget has been completed and is attached as Attachment 4 to this Work Letter (the
“Conceptual Budget”). 
 2.2. Plans. 

(a) Conceptual Plans. Tenant has prepared a conceptual plan for the Tenant Improvements that has been approved by Landlord and is
attached as Attachment 5 to this Work Letter (the “Conceptual Plans”). 
 (b) Draft Plans.
Landlord shall prepare draft plans (“Draft Plans”) for the Tenant Improvements that (1) are consistent with and are logical evolutions of the Conceptual Plans, (2) incorporate Permitted Changes (as defined in
Section 2.3(c) below), and (3) incorporate any other Landlord-requested Changes approved in writing by Tenant, if required by the terms of this Work Letter. The Draft Plans shall contain sufficient information and detail to
accurately describe the proposed design, and shall reflect consideration of adjacencies, process flows, HVAC zoning and pressurization, building circulation and exiting, and utility and electrical requirements. Tenant shall be solely responsible for
ensuring that the Draft Plans satisfy Tenant’s requirements for the Tenant Improvements. 
 (i) Tenant Approval of
Draft Plans. Promptly after the Draft Plans are completed, Landlord shall deliver the same to Tenant for Tenant’s approval, which approval may not be unreasonably withheld, conditioned or delayed, and may be withheld, conditioned or delayed
only if the Draft Plans are not consistent with or logical evolutions of the Conceptual Plans. Such Draft Plans shall be approved or disapproved by Tenant within five (5) business days after delivery to Tenant. If Tenant fails to notify
Landlord of disapproval within this five (5) business day period, the Draft Plans shall be deemed approved. If the Draft Plans are disapproved by Tenant, then Tenant shall at the time of such disapproval notify Landlord in writing of its
objections to such Draft Plans and the parties shall confer and negotiate in good faith to reach agreement on the Draft Plans. The Draft Plans approved or deemed approved by Tenant are referred to herein as the “Approved Draft
Plans.” 
 (c) Design Development Plans. Landlord shall prepare design development plans (“Design
Development Plans”) for the Tenant Improvements that (1) are consistent with and are logical evolutions of the Approved Draft Plans, (2) incorporate Permitted Changes (as defined in Section 2.3(c) below), and
(3) incorporate any other Landlord-requested Changes approved in writing by Tenant, if required by the terms of this Work Letter. 
 (i) Tenant Approval of Design Development Plans. Promptly after the Design Development Plans are completed, Landlord shall deliver the same to Tenant for Tenant’s approval, which approval may
not be unreasonably withheld, conditioned or delayed, and may be withheld, conditioned or delayed only if the Design Development Plans are not consistent with or logical evolutions of the Approved Draft Plans. Such Design Development Plans shall be
approved or disapproved by Tenant within five (5) business days after delivery to Tenant. If Tenant fails to notify Landlord of disapproval within this five (5) business day period, the Design Development Plans shall be deemed approved. If
the Design Development Plans are disapproved 

  
 B-2

 
disapproved by Tenant, then Tenant shall at the time of such disapproval notify Landlord in writing of its objections to such Design Development Plans and the parties shall confer and negotiate
in good faith to reach agreement on the Design Development Plans. The Design Development Plans approved or deemed approved by Tenant are referred to herein as the “Approved Design Development Plans.” 

(d) Permit Set Plans. Landlord shall prepare permit set plans (“Permit Set Plans”) for the Tenant Improvements
that (1) are consistent with and are logical evolutions of the Approved Design Development Plans, (2) incorporate Permitted Changes (as defined in Section 2.3(c) below), and (3) incorporate any other Landlord-requested
Changes approved in writing by Tenant, if required by the terms of this Work Letter. 
 (i) Tenant Approval of Permit Set
Plans. Promptly after the Permit Set Plans are completed, Landlord shall deliver the same to Tenant for Tenant’s approval, which approval may not be unreasonably withheld, conditioned or delayed, and may be withheld, conditioned or delayed
only if the Permit Set Plans are not consistent with or logical evolutions of the Approved Design Development Plans. Such Permit Set Plans shall be approved or disapproved by Tenant within ten (10) days after delivery to Tenant. If Tenant fails
to notify Landlord of disapproval within this ten (10) day period, the Permit Set Plans shall be deemed approved. If the Permit Set Plans are disapproved by Tenant, then Tenant shall at the time of such disapproval notify Landlord in writing of
its objections to such Permit Set Plans and the parties shall confer and negotiate in good faith to reach agreement on the Permit Set Plans. The Permit Set Plans approved or deemed approved by Tenant are referred to herein as the “Approved
Permit Set Plans.” 
 (e) Final Plans. Landlord shall prepare final plans (“Final Plans”) for
the Tenant Improvements that (1) are consistent with and are logical evolutions of the Approved Permit Set Plans, (2) incorporate Permitted Changes (as defined in Section 2.3(c) below), and (3) incorporate any other
Landlord-requested Changes approved in writing by Tenant, if required by the terms of this Work Letter. 
 (i) Tenant
Approval of Final Plans. Promptly after the Final Plans are completed, Landlord shall deliver the same to Tenant for Tenant’s approval, which approval may not be unreasonably withheld, conditioned or delayed, and may be withheld,
conditioned or delayed only if the Permit Set Plans are not consistent with or logical evolutions of the Approved Permit Set Plans. Such Final Plans shall be approved or disapproved by Tenant within ten (10) days after delivery to Tenant. If
Tenant fails to notify Landlord of disapproval within this ten (10) day period, the Final Plans shall be deemed approved. If the Final Plans are disapproved by Tenant, then Tenant shall at the time of such disapproval notify Landlord in writing of
its objections to such Final Plans and the parties shall confer and negotiate in good faith to reach agreement on the Final Plans. The Final Plans approved or deemed approved by Tenant, together with any Changes made in accordance with this Work
Letter, are referred to herein as the “Approved Plans.” 
 2.3. Changes to Tenant Improvements. Any
changes to the Final Plans or the Approved Plans (each, a “Change”) requested by Landlord or Tenant (other than Permitted Changes made by Landlord) shall be requested and instituted in accordance with the provisions of this
Article 3 and shall be subject to the written approval of the other party in accordance with this Work Letter. 
 (a)
Changes Requested by Tenant. 
 (i) Tenant Change Order Request. Tenant may request Changes after Tenant approves
the Final Plans or the Approved Plans, as applicable, by notifying Landlord thereof in writing in substantially the same form as the AIA standard change order form (a “Tenant Change Order Request”), which Tenant Change Order Request
shall detail the nature and extent of any requested Changes, including, without limitation, (A) the Change, (B) the party required to perform the Change and (C) any modification of the Final Plans or the Approved Plans, as applicable,
or the respective Schedule necessitated by the Change. 
 (ii) Landlord’s Approval of Changes. All Tenant-requested
Changes shall be subject to Landlord’s prior written approval, which shall not be unreasonably withheld. 

  
 B-3

 
Landlord shall have five (5) business days after receipt of a Tenant Change Order Request to notify Tenant in writing of Landlord’s approval or disapproval of any such Tenant-requested
Change. If Landlord does not approve in writing a Tenant Change Order Request, then such Tenant Change Order Request shall be deemed approved. 
 (b) Changes Requested by Landlord. 
 (i) Landlord Change Order
Request. Tenant’s consent shall not be required in connection with Landlord-requested Permitted Changes to the Tenant Improvements. Other than Permitted Changes, Landlord may request Changes after Tenant approves the Approved Plans by
notifying Tenant thereof in writing in substantially the same form as the AIA standard change order form (a “Landlord Change Order Request”), which Landlord Change Order Request shall detail the nature and extent of any requested
Changes, including, without limitation, (A) the Change, (B) the party required to perform the Change and (C) any modification of the Approved Plans or the respective Schedule necessitated by the Change. If the nature of a Change
requires revisions to the Approved Plans, then Landlord shall be solely responsible for the cost and expense of such revisions and such costs and expenses shall not be included in TI Costs. 

(ii) Tenant’s Approval of Change. Tenant shall have five (5) business days after receipt of a Landlord Change Order
Request to notify Landlord in writing of Tenant’s approval or rejection of the Landlord-requested Change, which approval shall not be unreasonably withheld. Tenant’s failure to respond within such five (5) business day period shall be
deemed approval by Tenant 
 (c) Permitted Changes. For purposes of this Work Letter, a “Permitted
Change” shall mean (A) minor field changes, (B) changes required by any Governmental Authority, (C) any other changes that (1) do not materially and adversely affect the building structure, roof, or building service
equipment to be constructed as part of the Tenant Improvements, (2) do not materially change the size, cost, configuration, or overall appearance of the Tenant Improvements or Tenant’s ability to operate its business in the Building and
(3) will not extend the Scheduled Completion Date of the Tenant Improvements (as set forth in the Tenant Improvement Schedule) beyond February 28, 2010 (as such date may be extended due to Force Majeure), and (D) ordinary development
of the Approved Plans in a manner not inconsistent with the Approved Plans; provided that, in the case of (A), (C) and (D) above, Permitted Changes that, in the aggregate, exceed the Cap (as defined below) shall require
Tenant’s approval, which approval shall not be unreasonably withheld, conditioned or delayed. 
 (d) Revised Budgets
Reflecting Changes. Notwithstanding anything in the Lease or this Work Letter to the contrary, changes to a Budget to reflect approved Landlord- or Tenant-requested Changes and Permitted Changes shall not require Tenant’s approval.

 3. Landlord Responsibilities. Landlord shall construct the Tenant Improvements using the Tenant Approved Vendors at Landlord’s
sole cost and expense in accordance with the Approved Plans (as defined below). Landlord shall not accept any bids or change orders not approved by Tenant in accordance with this Work Letter that add more than Ten Thousand Dollars ($10,000) in any
one instance or One Hundred Thousand Dollars ($100,000) in the aggregate to TI Costs (the “Cap”). Tenant shall provide its approval or disapproval of such bids and change orders within five (5) days following submission of the
same by Landlord, and if Tenant fails to provide such approval or disapproval within said period, then such submission shall be deemed approved by Tenant. In addition, Landlord shall: 

3.1. Cause the Tenant Improvements to be constructed using the design/bid method; 

3.2. Landlord shall incorporate into its contract with General Contractor the minimum performance requirements specified in Attachment
6 to this Work Letter; 
 3.3. Cause Landlord’s Project Manager and Third Party Manager to participate in weekly
coordination meetings; 
 3.4. Ensure that a project website for the sharing of information and storage of project data and
documents (similar to Project Path http://www.37signals.com) related to the Tenant 

  
 B-4

 
Improvements is developed and maintained for the duration of the construction of the Tenant Improvements; 
 3.5. Provide to Tenant four (4) sets of blueprints at each plan review stage; 

3.6. Cause all final drawings to be completed on AutoCAD and specifications to be written using Microsoft Word, and obligate the Tenant
Approved Vendors to convey title to all final drawings and specifications to Tenant promptly after completion of the Tenant Improvements; 
 3.7. Cause Architect to provide to Tenant a complete set of updated, as-built drawings and specifications upon Substantial Completion of the Tenant Improvements in both electronic and paper formats, with
drawing files to be in AutoCAD and PDF formats, and specifications to be in Microsoft Word; 
 3.8. Coordinate cost analysis and
value engineering throughout all phases of design and construction; 
 3.9. Coordinate reviews of the Tenant Improvements with
relevant City officials to develop project criteria; 
 3.10. Require representatives of the Tenant Approved Vendors to attend
weekly job site meetings; 
 3.11. Monitor Tenant Improvements costs, Permitted Changes, Tenant Change Order Requests and
Landlord Change Order Requests and keep Tenant informed of the same in a timely manner, including, without limitation, the issuance of monthly status reports; 
 3.12. Monitor construction progress and quality and keep Tenant informed of the same in a timely manner; 
 3.13. Coordinate all FAT, SAT and commissioning activities as detailed in Exhibit N to the Lease; 
 3.14. Give Tenant’s Authorized Representative reasonable prior notice of start-up of the Building’s utility systems; and 
 3.15. Complete the items of work listed on Attachment 7 to this Work Letter at Landlord’s sole cost and expense (except in the case of replacing the Building’s roof, the cost of which
shall be paid one-half (1/2) by Landlord and one-half (1/2) by Tenant as part of the Tenant Improvements). 
 Notwithstanding anything
in the Lease or this Work Letter to the contrary, Landlord shall only be responsible for constructing the Tenant Improvements in accordance with the Approved Plans and shall not in any way be responsible for ensuring that the Tenant Improvements
satisfy the requirements of Governmental Authorities (including, without limitation, the Food and Drug Administration) regarding use of the Premises or any portion thereof as a “clean room” in accordance with good manufacturing purposes or
for obtaining validation or licensing from any such Governmental Authorities, the responsibility for which shall be borne exclusively by Tenant. 
 4. Requests for Consent. Except as otherwise provided in this Work Letter, Tenant shall respond to all requests for consents, approvals or directions made by Landlord pursuant to this Work Letter
within five (5) days following Tenant’s receipt of such request. Tenant’s failure to respond within such five (5) day period shall be deemed approval by Tenant. Whenever consent or approval of either party is required, that party
shall not unreasonably withhold such consent or approval, except as may be expressly set forth to the contrary in this Work Letter. 
 5.
Miscellaneous. 
 5.1. Headings, Etc. Where applicable in this Work Letter, the singular includes the plural and
the masculine or neuter includes the masculine, feminine and neuter. The section 

  
 B-5

 
headings of this Work Letter are not a part of this Work Letter and shall have no effect upon the construction or interpretation of any part hereof. 

5.2. Time of the Essence. Time is of the essence with respect to the performance of every provision of this Work Letter in which
time of performance is a factor. 
 5.3. Entire Agreement. The terms of this Work Letter are intended by the parties as a
final expression of their agreement with respect to the terms as are included herein, and may not be contradicted by evidence of any prior or contemporaneous agreement, other than the Lease. 

5.4. Invalid Provisions. Any provision of this Work Letter that shall prove to be invalid, void or illegal shall in no way affect,
impair or invalidate any other provision hereof, and all other provisions of this Work Letter shall remain in full force and effect and shall be interpreted as if the invalid, void or illegal provision did not exist. 

5.5. Construction. The language in all parts of this Work Letter shall be in all cases construed as a whole according to its fair
meaning and not strictly for or against either Landlord or Tenant. 
 5.6. Assigns. Each of the covenants, conditions and
agreements herein contained shall inure to the benefit of and shall apply to and be binding upon the parties hereto and their respective heirs; legatees; devisees; executors; administrators; and permitted successors, assigns, sublessees. Nothing in
this Section 5.6 shall in any way alter the provisions of the Lease restricting assignment or subletting. 
 5.7.
Authority. Each party warrants and represents to the other that the individual or individuals signing this Work Letter have the power, authority and legal capacity to sign this Work Letter on behalf of and to bind all entities, corporations,
partnerships, limited liability companies, joint venturers or other organizations and entities on whose behalf said individual or individuals have signed. 
 5.8. Counterparts. This Work Letter may be executed in one or more counterparts, each of which, when taken together, shall constitute one and the same document. 

5.9. Attachments. The following Attachments are hereby incorporated into this Work Letter by this reference. 

Attachment 1: Schedule 
 Attachment 2: MEP Engineer’s Scope of Work 
 Attachment 3:
Structural Engineer’s Scope of Work 
 Attachment 4: Conceptual Budget 

Attachment 5: Conceptual Plans 
 Attachment 6: General Contractor Minimum Performance Requirements 

Attachment 7: Landlord’s Work 
 [REMAINDER OF THIS PAGE INTENTIONALLY LEFT BLANK] 

  
 B-6

 IN WITNESS WHEREOF, Landlord and Tenant have executed this Work Letter to be effective on
the date first above written. 
  

			
	LANDLORD:
	
	 BMR-GATEWAY BOULEVARD LLC,
 a Delaware limited liability company

		
	By:	 	 /s/ John F. Wilson, II

	Name:	 	 John F. Wilson, II

	Title:	 	 Executive V.P.

	
	TENANT:
	
	 REVANCE THERAPEUTICS, INC.,
 a Delaware corporation

		
	By:	 	 /s/ L. Daniel Browne

	Name:	 	 L. Daniel Browne

	Title:	 	 President / CEO

  
 B-7

	
	

 ATTACHMENT 1 TO EXHIBIT B 

SCHEDULE 
 XL CONSTRUCTION 
 DGA 

AEI 
 CRB 
 XL PROJECT No.: 3052 REVANCE THERAPEUTICS
Headquarters and Manufacturing Facility NEWARK Proposed Construction Schedule Issued: 03/5/08 
 4th Quarter 1st
Quarter 2nd Quarter 3rd Quarter 4th Quarter 1st Quarter 2nd Quarter 3rd Quarter 4th Quart 
 ID Task Name
Duration Start Finish Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov 
 1 PRECONSTRUCTION 380 days Mon 10/15/07 Thu 4/9/09 

2 BASIS OF DESIGN 30 days Mon 3/10/08 Fri 4/18/08 BASIS OF DESIGN 

3 Final Basis of Design 4 wks Mon 3/10/08 Fri 4/4/08 3/10 Final Basis of Design 

4 BOD Review 2 wks Mon 4/7/08 Fri 4/18/08 4/7 BOD Review 

5 BOD Approval 0 days Fri 4/18/08 Fri 4/18/08 4/18 BOD Approval 

6 PROCURE SITE FOR CONSTRUCTION’ 35 days Mon 3/10/08 Fri 4/25/08 PROCURE SITE FOR CONSTRUCTION* 

7 Finalize Search 0 days Mon 3/10/08 Mon 3/10/08 3/10 Finalize Search 

8 Negotiate Lease 7 wks Mon 3/10/08 Fri 4/25/08 3/10 Negotiate Lease 

9 Sign Lease 0 days Fri 4/25/08 Fri 4/25/08 4/25 Sign Lease 

10 PROJECT APPROVAL 0 days Mon 10/15/07 Mon 10/15/07 

11 Revance Board of Directors Project Approval 0 days Mon 10/15/07 Mon 10/15/07 5 Revance Board of Directors Project
Approval 
 12 DESIGN DOCUMENT DEVELOPMENT 80 days Mon 3/10/08 Fri 6/27/08 DESIGN DOCUMENT DEVELOPMENT

 13 CP-1 OPEN OFFICE DESIGN DEVELOPMENT 25 days Mon 3/10/08 Fri 4/11/08 CP-1 OPEN OFFICE DESIGN DEVELOPMENT

 14 Design 3 wks Mon 3/10/08 Fri 3/28/08 3/10 Design 

15 Issue for Permit 0 days Fri 3/28/08 Fri 3/28/08 3/28 Issue for Permit 

16 Issue for Review 0 days Fri 3/28/08 Fri 3/28/08 3/28 Issue for Review 

17 Fly Spec Review 1 wk Mon 3/31/08 Fri 4/4/08 3/31 Fly Spec Review 

18 Issue for Bidding 1 wk Mon 4/7/08 Fri 4/11/08 4/7 Issue for Bidding 

19 PREPURCHASE WFI, CLEAN STEAM, PW, DIESEL GENERATOR 30 days Mon 3/10/08 Fri 4/18/08 PREPURCHASE WFI, CLEAN STEAM, PW,
DIESEL GENERATOR 
 20 Issue Prepurchase Specifications 1 wk Mon 3/10/08 Fri 3/14/08 3/10 Issue Prepurchase
Specifications 
 21 Review Prepurchase Specifications 1 wk Mon 3/17/08 Fri 3/21/08 3/7 Review Prepurchase
Specifications 
 22 Develop Bid Packages 1 wk Mon 3/17/08 Fri 3/21/08 3/7 Develop Bid Packages 

23 Deisel Generator 13 days Fri 3/28/08 Wed 4/16/08 Deisel Generator 

24 Issue for Bid 0 days Fri 3/28/08 Fri 3/28/08 3/28 Issue for Bid 

25 Bids Due 1 wk Mon 3/31/08 Fri 4/4/08 3/31 Bids Due 

26 Bid Evaluation/RFA 3 days Mon 4/7/08 Wed 4/9/08 4/7 Bid Evaluation/RFA 

27 Revance Authorize Purchase 1 wk Thu 4/10/08 Wed 4/16/08 4/10 Revance Authorize Purchase 

28 WFI 15 days Fri 3/21/08 Fri 4/11/08 WFI 
 29 Issue for Bid 0 days Fri 3/21/08 Fri 3/21/08 3/21 Issue for Bid 
 30 Bids Due 2 wks Mon 3/24/08 Fri 4/4/08 3/24 Bids Due 
 31 Bid Evaluation/RFA 1 wk Mon 4/7/08 Fri 4/11/08 4/7 Bid Evaluation/RFA 
 32 Revance Authorize Purchase 0 days Fri 4/11/08 Fri 4/11/08 4/11 Revance Authorize Purchase 
 33 Clean Steam 15 days Fri 3/21/08 Fri 4/11/08 Clean Steam 
 34 Issue for Bid 0 days Fri 3/21/08 Fri 3/21/08 3/21 Issue for Bid 
 35 Bids Due 2 wks Mon 3/24/08 Fri 4/4/08 3/24 Bids Due 
 36 Bid Evaluation/RFA 1 wk Mon 4/7/08 Fri 4/11/08 4/7 Bid Evaluation/RFA 
 37 Revance Authorize Purchase 0 days Fri 4/11/08 Fri 4/11/08 4/11 Revance Authorize Purchase 
 38 Purified Water 20 days Fri 3/21/08 Fri 4/18/08 Purified Water 
 39 Issue for Bid 0 days Fri 3/21/08 Fri 3/21/08 3/31 Issue for Bid 
 40 Bids Due 3 wks Mon 3/24/08 Fri 4/11/08 3/24 Bids Due 
 41 Bid Evaluation/RFA 1 wk Mon 4/14/08 Fri 4/18/08 4/14 Bid Evaluation/RFA 
 42 Revance Authorize Purchase 0 days Fri 4/18/08 Fri 4/18/08 4/18 Revance Authorize Purchase 
 43 CP-2 OFFICE, MFG, R&D DESIGN DEVELOPMENT 80 days Mon 3/10/08 Fri 6/27/08 
 44 Design 10 wks Mon 3/10/08 Fri 5/16/08 3/10 Design 
 45 Issue for Planning 4 wks Mon 3/10/08 Fri 4/4/08 3/10 Issue for Planning 
 46 Issue for Permitting 2 wks Mon 5/19/08 Fri 5/30/08 5/19 Issue for Permitting 
 47 Issue for Review 1 wk Mon 6/2/08 Fri 6/6/08 6/2 Issue for Review 
 48 Fly Spec Review 1 wk Mon 6/9/08 Fri 6/13/08 6/9 Fly Spec Review 
 49 Issue for Bidding 2 wks Mon 6/16/08 Fri 6/27/08 6/16 Issue for Bidding 
 50 REGULATORY AGENCY PLAN CHECK & PERMITTING 113days Mon 3/31/08 Thu 9/4/08 
 51 CP-1-OFFICE PERMIT 23 days Mon 3/31/08 Wed 4/30/08 CP-1—OFFICE PERMIT 
 52 First City Plan Check 4 wks Mon 3/31/08 Fri 4/25/08 3/31 First City Plan Check 
 53 Office Permit Issued 0 days Wed 4/30/08 Wed 4/30/08 4/30 Office Permit Issued 
 54 BAAQMD PERMITTING 100 days Thu 4/17/08 Thu 9/4/08 BAAQMD PERMITTING 
 55 Submit Information for Approval 4 wks Thu 4/17/08 Wed 5/14/08 4/17 Submit Information for Approval 
 56 Obtain Approvals 16 wks Thu 5/15/08 Thu 9/4/08 5/15 Obtain Approvals 
 57 CP-2—MFG & R&D MODIFICATIONS 75 days Mon 4/7/08 Mon 7/21/08 CP-2 - MFG & R&D MODIFICATIONS 
 58 City Planning Review 6 wks Mon 4/7/08 Fri 5/16/08 4/7 City Planning Review 
 59 First City Plan Check 4 wks Mon 6/2/08 Fri 6/27/08 6/2 First City Plan Check 
 60 Team Respond To Plan Check Comments 1 wk Mon 6/30/08 Mon 7/7/08 6/30 Team Respond To Plan Check Comments 
 61 Second City Plan Check 2 wks Tue 7/8/08 Mon 7/21/08 7/8 Second City Plan Check 
 62 Building Office/ Mfg./R&D Labs Permit Issued 0 days Mon 7/21/08 Mon 7/21/08 7/21 Building Office/ Mfg./R&D Labs Permit Issued 

63 CONTRACTOR SELECTION, ESTIMATING, BUYOUT & GMP 93 days Mon 3/31/08 Thu 8/7/08 

64 BUDGETING 10 days Mon 4/7/08 Fri 4/18/08 BUDGETING CONTRACTOR SELECTION, ESTIMATING, BUYOUT & GMP 

65 CP-2 Design Development Budget 2 wks Mon 4/7/08 Fri 4/18/08 4/7 CP-2 Design Development Budget 

66 SUBCONTRACTOR BUYOUT 90 days Mon 3/31/08 Mon 8/4/08 SUBCONTRACTOR BUYOUT 

Page 1 Printed. Fri 3/7/08 

	
	

 XL CONSTRUCTION 
 DGA 
 AEI 

CRB 
 XL PROJECT No.: 3052 
 REVANCE THERAPEUTICS
Headquarters and Manufacturing Facility 
 NEWARK Proposed Construction Schedule 

Issued: 03/5/08 
 ID Task Name Duration Start Finish 
 67 Bid CP-1
Office 23 days Mon 3/31/08 Wed 4/30/08 
 68 XL Prepare ITB’s/Subcontractor Approval 1 wk Mon 3/31/08 Fri
4/4/08 
 69 Bid Period 2 wks Mon 4/14/08 Fri 4/25/08 

70 Bids Due 0 days Fri 4/25/08 Fri 4/25/08 
 71 Evaluation Period 3 days Mon 4/28/08 Wed 4/30/08 

72 GMP Submitted 0 days Wed 4/30/08 Wed 4/30/08 
 73 Bid CP-2 OFFICE, MFG and R&D 25 days Mon 6/30/08 Mon 8/4/08 
 74 XL Prepare ITB’s/Subcontractor Approval 2 wks Mon 6/30/08 Mon 7/14/08 
 75 Bid Period 2 wks Tue 7/15/08 Mon 7/28/08 
 76
Bids Due 0 days Mon 7/28/08 Mon 7/28/08 
 77 Evaluation Period 1 wk Tue 7/29/08 Mon 8/4/08 

78 GMP Submitted 0 days Mon 8/4/08 Mon 8/4/08 
 79 GUARANTEED MAXIMUM PRICE 70 days Thu 5/1/08 Thu 8/7/08 
 80 CP-1 GMP Approval 3 days Thu 5/1/08 Mon 5/5/08 

81 OK to Proceed with CP-1 0 days Mon 5/5/08 Mon 5/5/08 

82 CP-2 GMP Approval 3 days Tue 8/5/08 Thu 8/7/08 
 83 OK to Proceed with CP-2 0 days Thu 8/7/08 Thu 8/7/08 
 84 PROCUREMENT 280 days Mon 3/10/08 Thu 4/9/09 
 85
CONSULTANT / VENDOR PROCUREMENT 100 days Mon 3/10/08 Mon 7/28/08 
 86 Tele / Data System 36 days Mon 3/10/08 Mon
4/28/08 
 87 Determine Revance IT Dep’t to Provide Design Dev. Info 0 days Mon 3/10/08 Mon 3/10/08

 88 Tele/Data System Design 4 wks Mon 3/10/08 Fri 4/4/08 

89 Bid Structured Cabling 2 wks Mon 4/7/08 Fri 4/18/08 

90 Bids Due 0 days Mon 4/21/08 Mon 4/21/08 
 91 Evaluation Period 1 wk Tue 4/22/08 Mon 4/28/08 

92 Sub Selected 0 days Mon 4/28/08 Mon 4/28/08 
 93 High Density Storage 100 days Mon 3/10/08 Mon 7/28/08 
 94 Select Vendor 0 days Mon 3/10/08 Mon 3/10/08 

95 Design 8 wks Mon 3/10/08 Fri 5/2/08 
 96 Fabrication & Deliver 12 wks Mon 5/5/08 Mon 7/28/08 
 97 Security 40 days Mon 3/10/08 Fri 5/2/08 
 98
Design 8 wks Mon 3/10/08 Fri 5/2/08 
 99 Furniture 35 days Mon 3/10/08 Fri 4/25/08 

100 Select Vendor and Negotiate Contract 3 wks Mon 3/10/08 Fri 3/28/08 

101 Finalize Layout and Product Specification 4 wks Mon 3/31/08 Fri 4/25/08 

102 Pre- Purchase Manufacturing Equip. & Utility Systems 280 days Mon 3/10/08 Thu 4/9/09 

103 GMP Autoclave 190 days Mon 3/10/08 Thu 12/4/08 

104 Bid, Evaluate & Issue P.O. 6 wks Mon 3/10/08 Fri 4/18/08 

105 Shop Drawings Submittal & Approval 10 wks Mon 4/21/08 Fri 6/27/08 

106 Fabricate & Delivery Autoclave 22 wks Mon 6/30/08 Thu 12/4/08 

107 GMP Glass washer 150 days Mon 3/10/08 Tue 10/7/08 

108 Bid, Evaluate & Issue P.O. 6 wks Mon 3/10/08 Fri 4/18/08 

109 Shop Drawings Submittal & Approval 10 wks Mon 4/21/08 Fri 6/27/08 

110 Fabricate & Delivery 14 wks Mon 6/30/08 Tue 10/7/08 

111 Bio Safety Cabinets 160 days Mon 3/10/08 Tue 10/21/08 

112 Bid, Evaluate & Issue P.O. 6 wks Mon 3/10/08 Fri 4/18/08 

113 Shop Drawings Submittal & Approval 10 wks Mon 4/21/08 Fri 6/27/08 

114 Delivery 16 wks Mon 6/30/08 Tue 10/21/08 
 115 TFF Skids 215 days Mon 3/10/08 Thu 1/8/09 
 116
Bid, Evaluate & Issue P.O. 6 wks Mon 3/10/08 Fri 4/18/08 
 117 Shop Drawings Submittal & Approval 10 wks
Mon 4/21/08 Fri 6/27/08 
 118 Delivery 27 wks Mon 6/30/08 Thu 1/8/09 

119 Lyophilizers 280 days Mon 3/10/08 Thu 4/9/09 
 120 Bid, Evaluate & Issue P.O. 12 wks Mon 3/10/08 Fri 5/30/08 
 121 Shop Drawings Submittal & Approval 12 wks Mon 6/2/08 Mon 8/25/08 
 122 Delivery 32 wks Tue 8/26/08 Thu 4/9/09 
 123
Fermentor Skids 205 days Mon 3/10/08 Thu 12/25/08 
 124 Bid, Evaluate & Issue P.O. 6 wks Mon 3/10/08
Fri 4/18/08 
 125 Shop Drawings Submittal & Approval 10 wks Mon 4/21/08 Fri 6/27/08 

126 Delivery 25 wks Mon 6/30/08 Thu 12/25/08 
 127 Purified Water System 190 days Mon 4/21/08 Thu 1/15/09 
 128 Prepare Submittals 10 wks Mon 4/21/08 Fri 6/27/08 
 129 Review and Approve Submittals 4 wks Mon 6/30/08 Mon 7/28/08 
 130 Fabricate & Delivery Skid 24 wks Tue 7/29/08 Thu 1/15/09 
 131 WFI System 150 days Mon 4/14/08 Tue 11/11/08 

132 Prepare Submittals 10 wks Mon 4/14/08 Fri 6/20/08 

133 Review and Approve Submittals 4 wks Mon 6/23/08 Mon 7/21/08 

134 Fabricate & Delivery Skid 16 wks Tue 7/22/08 Tue 11/11/08 

135 Clean Steam Generator 150 days Mon 4/14/08 Tue 11/11/08 

4th Quarter 1st Quarter 2nd Quarter 3rd Quarter 4th Quarter 1st Quarter 2nd Quarter 3rd Quarter 4th Quart 

Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov 

Bid CP-1 Office 
 3/31 XL Prepare ITB’s/Subcontractor Approval 

4/14 Bid Period 
 4/25 Bids Due 
 4/28 Evaluation Period 

4/30 GMP Submitted 
 Bid CP-2 OFFICE, MFG and R&D 
 6/30 (XL Prepare
ITB’s/Subcontractor Approval 
 7/15 Bid Period 

7/28 Bids Due 
 7/29 Evaluation Period 
 8/4 GMP Submitted

 GUARANTEED MAXIMUM PRICE 
 5/1 CP-1 GMP Approval 
 5/5 OK to Proceed with CP-1

 8/5 CP-2 GMP Approval 
 8/7 OK to Proceed with CP-2 
 PROCUREMENT

 CONSULTANT / VENDOR PROCUREMENT 
 Tele / Data System 
 3/10 Determine Revance IT
Dep’t to Provide Design Dev. Info 
 3/10 Tele/Data System Design 

4/7 Bid Structured Cabling 
 4/21 Bids Due 
 4/22 Evaluation Period 

4/28 Sub Selected 
 High Density Storage 
 3/10 Select Vendor

 3/10 Design 
 5/5 Fabrication & Deliver 
 Security

 3/10 Design 
 Furniture 
 3/10 Select Vendor and Negotiate
Contract 
 3/31 Finalize Layout and Product Specification 

Pre- Purchase Manufacturing Equip. & Utility Systems 

GMP Autoclave 
 3/10 Bid, Evaluate & Issue P.O. 
 4/21 Shop
Drawings Submittal & Approval 
 6/30 Fabricate & Delivery Autoclave 

GMP Glass washer 
 3/10 Bid, Evaluate & Issue P.O. 
 4/21 Shop
Drawings Submittal & Approval 
 6/30 Fabricate & Delivery 

Bio Safety Cabinets 
 3/10 Bid, Evaluate & Issue P.O. 
 4/21 Shop
Drawings Submittal & Approval 
 6/30 Delivery 

TFF Skids 
 3/10 Bid, Evaluate & Issue P.O. 
 4/21 Shop
Drawings Submittal & Approval 
 6/30 Delivery 

Lyophilizers 
 3/10 Bid, Evaluate & Issue P.O. 
 6/2 Shop
Drawings Submittal & Approval 
 8/26 Delivery 

Fermentor Skids 
 3/10 Bid, Evaluate & Issue P.O. 
 4/21 Shop
Drawings Submittal & Approval 
 6/30 Delivery 

Purified Water System 
 4/21 Prepare Submittals 
 6/30 Review and Approve
Submittals 
 7/29 Fabricate & Delivery Skid 

WFI System 
 4/14 Prepare Submittals 
 6/23 Review and Approve
Submittals 
 7/22 Fabricate & Delivery Skid 

Clean Steam Generator 
 Page 2 Printed: Fri 3/7/08 

	
	

 XL CONSTRUCTION 
 DGA 
 AEI 

CRB 
 XL PROJECT No.: 3052 REVANCE THERAPEUTICS Issued: 03/5/08 
 Headquarters and Manufacturing Facility 
 NEWARK

 Proposed Construction Schedule 
 ID Task Name Duration Start Finish 
 136 Prepare
Submittals 10 wks Mon 4/14/08 Fri 6/20/08 
 137 Review and Approve Submittals 4 wks Mon 6/23/08 Mon 7/21/08

 138 Fabricate & Delivery Generator 16 wks Tue 7/22/08 Tue 11/11/08 

139 Steam Boilers 140 days Fri 8/8/08 Tue 2/24/09 
 140 Bid, Evaluate & Issue P.O. 6 wks Fri 8/8/08 Fri 9/19/08 
 141 Prepare Submittals 6 wks Mon 9/22/08 Fri 10/31/08 
 142 Review and Approve Submittals 4 wks Mon 11/3/08 Tue 12/2/08 
 143 Fabricate & Delivery Boilers 12 wks Wed 12/3/08 Tue 2/24/09 
 144 CP-1 OFFICE PROCUREMENT 203 days Mon 3/31/08 Tue 1/13/09 
 145 Generator 190 days Thu 4/17/08 Tue 1/13/09 

146 Prepare Shop Drawings 6 wks Thu 4/17/08 Wed 5/28/08 

147 Review and Approve Shop Drawings 2 wks Thu 5/29/08 Wed 6/11/08 

148 Fabricate & Deliver Generators 30 wks Thu 6/12/08 Tue 1/13/09 

149 Architectural Casework 60 days Tue 5/6/08 Tue 7/29/08 

150 Prepare Architectural Casework Shop Drawings 3 wks Tue 5/6/08 Mon 5/26/08 

151 Review and Approve Shop Drawings 1 wk Tue 5/27/08 Mon 6/2/08 

152 Fabricate & Ship Architectural Casework 8 wks Tue 6/3/08 Tue 7/29/08 

153 Carpet/Sheet Goods 30 days Tue 5/6/08 Mon 6/16/08 

154 Prepare Flooring Shop Drawings 1 wk Tue 5/6/08 Mon 5/12/08 

155 Review and Approve Shop Drawings 1 wk Tue 5/13/08 Mon 5/19/08 

156 Fabricate & Ship Carpet / Sheet Goods 4 wks Tue 5/20/08 Mon 6/16/08 

157 Doors/Frames/Hardware 55 days Tue 5/6/08 Tue 7/22/08 

158 Prepare Door and Hardware Submittal 3 wks Tue 5/6/08 Mon 5/26/08 

159 Review and Approve Submittal 2 wks Tue 5/27/08 Mon 6/9/08 

160 Fabricate & Ship Doors and Hardware 6 wks Tue 6/10/08 Tue 7/22/08 

161 Light Fixtures 55 days Tue 5/6/08 Tue 7/22/08 
 162 Prepare Lighting Submittal 3 wks Tue 5/6/08 Mon 5/26/08 
 163 Review and Approve Lighting Submittal 2 wks Tue 5/27/08 Mon 6/9/08 
 164 Fabricate & Ship Lights 6 wks Tue 6/10/08 Tue 7/22/08 
 165 MEP Coordination Drawings 18 days Tue 5/6/08 Thu 5/29/08 
 166 Develop Shop Drawings & Coordinate 1 wk Tue 5/6/08 Mon 5/12/08 
 167 Review & Approve Shop Drawings 3 days Tue 5/13/08 Thu 5/15/08 
 168 Fabricate Ductwork 2 wks Fri 5/16/08 Thu 5/29/08 
 169 HVAC Equipment 45 days Tue 5/6/08 Tue 7/8/08 

170 AIR TERMINALS 45 days Tue 5/6/08 Tue 7/8/08 
 171 Prepare Submittals 2 wks Tue 5/6/08 Mon 5/19/08 

172 Review and Approve Submittals 1 wk Tue 5/20/08 Mon 5/26/08 

173 Fabricate & Delivery Equipment 6 wks Tue 5/27/08 Tue 7/8/08 

174 Specialty Ceiling Systems 50 days Tue 5/6/08 Tue 7/15/08 

175 Prepare Submittals 1 wk Tue 5/6/08 Mon 5/12/08 

176 Review and Approve Submittals 1 wk Tue 5/13/08 Mon 5/19/08 

177 Fabricate & Delivery Ceiling Systems 8 wks Tue 5/20/08 Tue 7/15/08 

178 Fire Alarm System 60 days Tue 5/6/08 Tue 7/29/08 

179 Prepare Submittals 2 wks Tue 5/6/08 Mon 5/19/08 

180 Review and Approve Submittals 2 wks Tue 5/20/08 Mon 6/2/08 

181 Fabricate & Delivery Ceiling Systems 8 wks Tue 6/3/08 Tue 7/29/08 

182 Furniture 40 days Mon 3/31/08 Fri 5/23/08 
 183 Order, Fabricate, and Ship Partitions 8 wks Mon 3/31/08 Fri 5/23/08 
 184 CP-2 MFG, R&D PROCUREMENT 170 days Thu 8/7/08 Tue 4/7/09 
 185 Fill Machine 170 days Thu 8/7/08 Tue 4/7/09 

186 Issue RFP 0 days Thu 8/7/08 Thu 8/7/08 
 187 Bid, Review & Authorization 6 wks Fri 8/8/08 Fri 9/19/08 
 188 Shop Drawings Submittal & Approval 10 wks Mon 9/22/08 Tue 12/2/08 
 189 Delivery 18 wks Wed 12/3/08 Tue 4/7/09 
 190
Light Fixtures 70 days Fri 8/8/08 Fri 11/14/08 
 191 Prepare Lighting Submittal 4 wks Fri 8/8/08 Thu 9/4/08

 192 Review and Approve Lighting Submittal 2 wks Fri 9/5/08 Fri 9/19/08 

193 Fabricate & Ship Lights 8 wks Mon 9/22/08 Fri 11/14/08 

194 Misc Structural Steel 60 days Fri 8/8/08 Fri 10/31/08 

195 Prepare Shop Drawings 4 wks Fri 8/8/08 Thu 9/4/08 

196 Structural & HVAC Platform Coordination 2 wks Fri 9/5/08 Fri 9/19/08 

197 Review and Approve Shop Drawings 1 wk Mon 9/22/08 Fri 9/26/08 

198 Fabricate & Deliver Steel 5 wks Mon 9/29/08 Fri 10/31/08 

199 Underground Utilities 25 days Fri 8/8/08 Fri 9/12/08 

200 Prepare Shop Drawings 3 wks Fri 8/8/08 Thu 8/28/08 

201 Review and Approve Shop Drawings 1 wk Fri 8/29/08 Thu 9/4/08 

202 Fabricate & Deliver Pipe 1 wk Fri 9/5/08 Fri 9/12/08 

203 Laboratory Casework 85 days Fri 8/8/08 Tue 12/9/08 

204 Prepare Shop Drawings 4 wks Fri 8/8/08 Thu 9/4/08 

4th Quarter 
 1st Quarter 2nd Quarter 3rd Quarter 4th Quarter 1st Quarter 2nd Quarter 3rd Quarter 4th Quart 
 Oct Nov Dec 
 Jan Feb Mar Apr May Jun Jul Aug Sep
Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov 
 4/14 Prepare Submittals 

6/23 Review and Approve Submittals 
 7/22 Fabricate & Delivery Generator 
 Steam
Boilers 
 8/8 Bid, Evaluate & Issue P.O. 

9/22 Prepare Submittals 
 11/3 Review and Approve Submittals 
 12/3 Fabricate
& Delivery Boilers 
 CP-1 OFFICE PROCUREMENT 

Generator 
 4/17 Prepare Shop Drawings 
 5/29 Review and
Approve Shop Drawings 
 6/12 Fabricate & Deliver Generators 

Architectural Casework 
 5/6 Prepare Architectural Casework Shop Drawings 

5/27 Review and Approve Shop Drawings 6/3 Fabricate & Ship Architectural Casework 

Carpet/Sheet Goods 
 5/6 Prepare Flooring Shop Drawings 
 5/13 Review
and Approve Shop Drawings 
 5/20 Fabricate & Ship Carpet / Sheet Goods 

Doors/Frames/Hardware 
 5/6 Prepare Door and Hardware Submittal 
 5/27
Review and Approve Submittal 
 6/10 Fabricate & Ship Doors and Hardware 

Light Fixtures 
 5/6 Prepare Lighting Submittal 
 5/27 Review and
Approve Lighting Submittal 
 6/10 Fabricate & Ship Lights 

MEP Coordination Drawings 
 5/6 Develop Shop Drawings & Coordinate 

5/13 Review & Approve Shop Drawings 
 5/16 Fabricate Ductwork 
 HVAC Equipment

 AIR TERMINALS 
 5/6 Prepare Submittals 
 5/20 Review and Approve
Submittals 
 5/27 Fabricate & Delivery Equipment 

Specialty Ceiling Systems 
 5/6 Prepare Submittals 
 5/13 Review and Approve
Submittals 
 5/20 Fabricate & Delivery Ceiling Systems 

Fire Alarm System 
 5/6 Prepare Submittals 
 5/20 Review and Approve
Submittals 
 6/3 Fabricate & Delivery Ceiling Systems 

Furniture 
 3/31 Order, Fabricate, and Ship Partitions 
 CP-2
MFG, R&D PROCUREMENT 
 Fill Machine 
 8/7 Issue RFP 
 8/8 Bid, Review &
Authorization 
 9/22 Shop Drawings Submittal & Approval 

12/3 Delivery 
 Light Fixtures 
 8/8 Prepare Lighting Submittal

 9/5 Review and Approve Lighting Submittal 

9/22 Fabricate & Ship Lights 
 Misc Structural Steel 
 8/8 Prepare Shop Drawings

 9/5 Structural & HVAC Platform Coordination 

9/22 Review and Approve Shop Drawings 
 9/29 Fabricate & Deliver Steel 

Underground Utilities 
 8/8 Prepare Shop Drawings 
 8/29 Review and Approve
Shop Drawings 
 9/5 Fabricate & Deliver Pipe 

Laboratory Casework 
 8/8 Prepare Shop Drawings 
 Page 3 Printed: Fri
3/7/08 

	
	

 XL CONSTRUCTION 
 DGA 
 AEI 

CRB 
 XL PROJECT No.: 3052 
 REVANCE THERAPEUTICS
Headquarters and Manufacturing Facility NEWARK 
 Proposed Construction Schedule 

ID Task Name Duration Start 
 Finish 
 205 Review and Approve Shop Drawings 3 wks
Fri 9/5/08 Fri 9/26/08 
 206 Fabricate & Deliver Casework 10 wks Mon 9/29/08 Tue 12/9/08 

207 Doors/Frames/Hardware 60 days Fri 8/8/08 Fri 10/31/08 

208 Prepare Door and Hardware Submittal 2 wks Fri 8/8/08 Thu 8/21/08 

209 Review and Approve Submittal 2 wks Fri 8/22/08 Thu 9/4/08 

210 Fabricate & Ship Doors and Hardware 8 wks Fri 9/5/08 Fri 10/31/08 

211 Cold Rooms 90 days Fri 8/8/08 Tue 12/16/08 
 212 Prepare Shop Drawings 8 wks Fri 8/8/08 Fri 10/3/08 
 213 Review and Approve Shop Drawings 2 wks Mon 10/6/08 Fri 10/17/08 
 214 Fabricate & Deliver Cold Room 8 wks Mon 10/20/08 Tue 12/16/08 
 215 Specialty Ceiling Systems 50 days Fri 8/8/08 Fri 10/17/08 
 Prepare Submittals 1 wk Fri 8/8/08 Thu 8/14/08 

217 Review and Approve Submittals 1 wk Fri 8/15/08 Thu 8/21/08 

218 Fabricate & Delivery Ceiling Systems 8 wks Fri 8/22/08 Fri 10/17/08 

219 Main Electrical Gear 75 days Fri 8/8/08 Fri 11/21/08 

220 Prepare Shop Drawings 3 wks Fri 8/8/08 Thu 8/28/08 

221 Review and Approve Shop Drawings 2 wks Fri 8/29/08 Fri 9/12/08 

222 Fabricate & Deliver Gear 1 wks Mon 9/15/08 Fri 11/21/08 

223 MEP Coordination Drawings 50 days Fri 8/8/08 Fri 10/17/08 

Develop Shop Drawings & Coordinate 4 wks Fri 8/8/08 Thu 9/4/08 

225 Review & Approve Shop Drawings 2 wks Fri 9/5/08 Fri 9/19/08 

226 Fabricate Ductwork 4 wks Mon 9/22/08 Fri 10/17/08 

HEPA Filters 65 days Fri 8/8/08 Fri 11/7/08 
 228 Prepare HEPA Submittal 3 wks Fri 8/8/08 Thu 8/28/08 
 229 Review and Approve Submittal 2 wks Fri 8/29/08 Fri 9/12/08 
 230 Fabricate & Ship HEPA Filters 8 wks Mon 9/15/08 Fri 11/7/08 
 231 Cooling Tower 55 days Fri 8/8/08 Fri 10/24/08 

232 Prepare Shop Drawings ( Cut Sheets for Structural Steel @ Roof) 1 wk Fri 8/8/08 Thu 8/14/08 

233 Review and Approve Shop Drawings 2 wks Fri 8/15/08 Thu 8/28/08 

234 Fabricate & Deliver Cooling Tower 8 wks Fri 8/29/08 Fri 10/24/08 

235 Mech Equipment (AHU, Chillers, EF, CDA & Air Treatment System & Vacuum Skid) 75 days Fri 8/8/08 Fri
11/21/08 
 236 Prepare Submittals 3 wks Fri 8/8/08 Thu 8/28/08 

237 Review and Approve Submittals 2 wks Fri 8/29/08 Fri 9/12/08 

238 Fabricate & Delivery Equipment 10 wks Mon 9/15/08 Fri 11/21/08 

239 JOBSITE MOBILIZATION 28 days Mon 4/28/08 Wed 6/4/08 

240 Deliver and Set Up Two Trailers 1 wk Mon 4/28/08 Fri 5/2/08 

241 Install Site Construction Fence 3 days Mon 5/5/08 Wed 5/7/08 

242 Install Scaffolding to Roof / Bid. Protection 2 wks Thu 5/8/08 Wed 5/21/08 

243 Install Building Temp Lighting 2 wks Thu 5/22/08 Wed 6/4/08 

244 CONSTRUCTION—BUILDING 288 days Mon 5/5/08 Wed 6/17/09 

245 OK To Proceed With Phase 1 Construction 0 days Mon 5/5/08 Mon 5/5/08 

246 PHASE 1:2ND FLOOR OPEN OFFICE 55 days Tue 5/6/08 Tue 7/22/08 

247 OPEN OFFICE BUILD OUT 55 days Tue 5/6/08 Tue 7/22/08 

248 Interior Demo 9 days Tue 5/6/08 Fri 5/16/08 
 249 Electrical Safe-Off 3 days Tue 5/6/08 Thu 5/8/08 
 250 Demo (E) T-Bar Ceiling 5 days Wed 5/7/08 Tue 5/13/08 
 251 Strategic Mechanical Demo 3 days Wed 5/14/08 Fri 5/16/08 
 252 Demo (E) Walls 2 days Mon 5/12/08 Tue 5/13/08 
 253 Misc. Demo Complete 0 days Tue 5/13/08 Tue 5/13/08 
 254 Overhead Rough-ln 14 days Mon 5/19/08 Thu 6/5/08 
 255 Modify Fire Sprinkler Piping 1 wk Mon 5/19/08 Fri 5/23/08 
 256 Rough In HVAC Duct Work 5 days Mon 5/26/08 Fri 5/30/08 
 257 Install Horizontal Duct mains & Branch lines 1 wk Mon 5/26/08 Fri 5/30/08 
 258 Rough In HW Piping 1 wk Wed 5/28/08 Tue 6/3/08 

259 Rough In Overhead Electric 7 days Wed 5/28/08 Thu 6/5/08 

260 Rough In Tele-Com Data Cable Trays 3 days Fri 5/30/08 Tue 6/3/08 

261 Over Head Rough In Complete 0 days Tue 6/3/08 Tue 6/3/08 

262 Wall Construction 12 days Mon 6/2/08 Tue 6/17/08 

263 Frame Full Height Walls 2 days Mon 6/2/08 Tue 6/3/08 

264 In Wall Electrical Rough In 2 days Tue 6/3/08 Wed 6/4/08 

265 Wall Inspection 0 days Wed 6/4/08 Wed 6/4/08 
 266 Install Drywall 1 Side 1 day Thu 6/5/08 Thu 6/5/08 
 267 Install Wall Insulation 1 day Fri 6/6/08 Fri 6/6/08 
 268 Rock Walls & Ceilings 1 day Fri 6/6/08 Fri 6/6/08 
 269 Screw Inspection 0 days Fri 6/6/08 Fri 6/6/08 

270 Tape and Finish Drywall 5 days Mon 6/9/08 Fri 6/13/08 

271 Install Aluminum Door & Window Frames 2 days Mon 6/16/08 Tue 6/17/08 

4th Quarter 1st Quarter 2nd Quarter 3rd Quarter 4th Quarter 1st Quarter 2nd Quarter 3rd Quarter 4th Quart 

Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov 

9/5 Review and Approve Shop Drawings 
 9/29 Fabricate & Deliver Casework 
 8/8
Prepare Door and Hardware Submittal 
 8/22 Review and Approve Submittal 

9/5 Fabricate & Ship Doors and Hardware 
 Prepare Shop Drawings 
 10/6 Review and Approve
Shop Drawings 
 10/20 Fabricate & Deliver Cold Room 

8/6 Prepare Submittals 
 8/15 Review and Approve Submittals 
 8/22
Fabricate & Delivery Ceiling Systems 
 8/8 Prepare Shop Drawings 

8/29 Review and Approve Shop Drawings 
 9/15 Fabricate & Deliver Gear 
 Develop
Shop Drawings & Coordinate 
 9/5 Review & Approve Shop Drawings 

9/22 Fabricate Ductwork 
 8/8 Prepare HEPA Submittal 
 8/29 Review and
Approve Submittal 
 9/15 Fabricate & Ship HEPA Filters 

8/8 Prepare Shop Drawings (Cut Sheets for Structural Steel @ Roof) 

8/15 Review and Approve Shop Drawings 
 8/29 Fabricate & Deliver Cooling Tower 
 8/8
Prepare Submittals 
 8/29 Review and Approve Submittals 

9/15 Fabricate & Delivery Equipment 
 JOBSITE MOBILIZATION 
 4/28 Deliver and Set Up Two
Trailers 
 5/5 | Install Site Construction Fence 

5/8 Install Scaffolding to Roof / Bid. Protection 
 5/22 Install Building Temp Lighting 
 5/5 OK To
Proceed With Phase 1 Construction 
 Interior Demo 

5/6 Electrical Safe-Off 
 5/7 Demo (E) T-Bar Ceiling 
 5/14 Strategic
Mechanical Demo 
 5/12 Demo (E) Walls 
 5/13 Misc. Demo Complete 
 Overhead Rough-In

 5/19 Modify Fire Sprinkler Piping 
 Rough In HVAC Duct Work 
 5/26 Install Horizontal
Duct mains & Branch lines 
 5/28 Rough In HW Piping 

5/28 Rough In Overhead Electric 
 5/30 Rough In Tele-Com Data Cable Trays 
 6/3 Over
Head Rough In Complete 
 Wall Construction 6/2 Frame Full Height Walls 

6/3 In Wall Electrical Rough In 
 6/4 Wall Inspection 
 6/5 Install Drywall 1 Side

 6/6 Install Wall insulation 
 6/6 Rock Walls & Ceilings 
 6/6 Screw
Inspection 
 6/9 Tape and Finish Drywall 

6/16 Install Aluminum Door & Window Frames 

Page 4 Printed: Fri 3/7/08 
 Issued: 03/5/08 

	
	

 XL CONSTRUCTION 
 DGA 
 AEI 

CRB 
 XL PROJECT No.: 3052 
 REVANCE THERAPEUTICS
Headquarters and Manufacturing Facility 
 NEWARK Proposed Construction Schedule 

issued: 03/5/08 
 ID Task Name Duration Start Finish 
 272 Walls
Construction Complete 0 days Tue 6/17/08 Tue 6/17/08 
 273 Ceiling Construction 30 days Tue 6/10/08 Tue 7/22/08

 274 Install T-bar Ceiling 1 wk Tue 6/10/08 Mon 6/16/08 

275 Install Specialty Ceiling 1 wk Wed 7/16/08 Tue 7/22/08 

276 Install Light Fixtures 1 wk Tue 6/10/08 Mon 6/16/08 

277 Install Registers 1 wk Tue 6/10/08 Mon 6/16/08 

278 Trim Fire Sprinkler Heads 3 days Tue 6/17/08 Thu 6/19/08 

279 Install Telephone/Data Cabling 1 wk Tue 6/17/08 Mon 6/23/08 

280 Above Ceiling Fire Inspection 0 days Mon 6/23/08 Mon 6/23/08 

281 Above Ceiling Building Inspection 0 days Tue 6/24/08 Tue 6/24/08 

282 Drop Ceiling Tiles 1 wk Wed 6/25/08 Tue 7/1/08 

283 Finishes 13 days Mon 6/16/08 Wed 7/2/08 
 284 Paint Walls 1 wk Mon 6/16/08 Fri 6/20/08 
 285
Trim Out Elect/Data 3 days Tue 6/24/08 Thu 6/26/08 
 286 Install Open Office Carpet 1 wk Thu 6/19/08 Wed 6/25/08

 287 Install Open Office Partitions / Hookup / Furniture 1 wk Thu 6/26/08 Wed 7/2/08 

288 Install Carpet Offices & Conference Rm. 2 days Mon 6/23/08 Tue 6/24/08 

289 Install Doors & Hardware 1 day Wed 6/25/08 Wed 6/25/08 

290 BATHROOM & SHOWER CONSTRUCTION 2 days Mon 6/23/08 Tue 6/24/08 

291 Paint Walls and Ceilings 2 days Mon 6/23/08 Tue 6/24/08 

292 1st Floor Bathroom Const Complete 0 days Tue 6/24/08 Tue 6/24/08 

293 Open Office Complete 0 days Wed 7/2/08 Wed 7/2/08 

294 City & Fire Inspections 2 days Thu 7/3/08 Mon 7/7/08 

295 Startup & Balance Office AHU’s 3 days Wed 6/25/08 Fri 6/27/08 

296 Temporary Certificate Of Occupancy for Office Area 0 days Mon 7/7/08 Mon 7/7/08 

297 PHASE 2: LABS/MANUFACTURING/OFFICE 167 days Thu 8/7/08 Thu 4/2/09 

298 OK To Proceed With Phase 2 Construction 0 days Thu 8/7/08 Thu 8/7/08 

299 DEMO 33 days Fri 8/8/08 Wed 9/24/08 
 300 Electrical Safe-Off 2 wks Fri 8/8/08 Thu 8/21/08 
 301 Demo (E) T-Bar Ceiling 2 wks Wed 8/20/08 Tue 9/2/08 
 302 Strategic Mechanical Demo 2 wks Wed 9/3/08 Wed 9/17/08 
 303 Demo (E) Walls 2 wks Thu 9/11/08 Wed 9/24/08 
 304 Misc. Demo Complete 0 days Wed 9/24/08 Wed 9/24/08 
 305 OPEN OFFICE BUILDOUT 98 days Fri 8/8/08 Fri 12/26/08 
 306 Below Slab Plumbing & Electrical 18 days Fri 8/8/08 Tue 9/2/08 
 307 Layout Trenches 2 days Fri 8/8/08 Mon 8/11/08 

308 Locate Underground Utilities 1 day Tue 8/12/08 Tue 8/12/08 

309 Saw cut and Remove Concrete 2 days Wed 8/13/08 Thu 8/14/08 

310 Excavate Trenches 2 days Fri 8/15/08 Mon 8/18/08 

311 Install Plumbing and Electrical 1 wk Tue 8/19/08 Mon 8/25/08 

312 Inspection 0 days Mon 8/25/08 Mon 8/25/08 
 313 Backfill Trenches 2 days Tue 8/26/08 Wed 8/27/08 
 314 Install Rebar 2 days Thu 8/28/08 Fri 8/29/08 

315 Inspection 0 days Fri 8/29/08 Fri 8/29/08 
 316 Patch Concrete 2 days Mon 9/1/08 Tue 9/2/08 

317 Below Slab Work Complete 0 days Tue 9/2/08 Tue 9/2/08 

318 Overhead Rough-in 22 days Wed 9/3/08 Fri 10/3/08 

319 Modify Fire Sprinkler Piping 1 wk Wed 9/3/08 Wed 9/10/08 

320 Rough In HVAC Duct Work 10 days Thu 9/11/08 Wed 9/24/08 

321 Install Horizontal Duct mains & Branch lines 2 wks Thu 9/11/08 Wed 9/24/08 

322 Rough In HW Piping 7 days Thu 9/25/08 Fri 10/3/08 

323 Rough In Overhead Electric 7 days Thu 9/25/08 Fri 10/3/08 

324 Rough In Tele-Com Data Cable Trays 1 wk Mon 9/29/08 Fri 10/3/08 

325 Overhead Rough In Complete 0 days Fri 10/3/08 Fri 10/3/08 

326 Wall Construction 23 days Mon 10/6/08 Wed 11/5/08 

327 Frame Full Height Walls ( Rated Walls & Coordinate With MEP) 1 wk Mon 10/6/08 Fri 10/10/08 

328 In Wall MEP Rough In 1 wk Mon 10/13/08 Fri 10/17/08 

329 Wall Inspection 0 days Fri 10/17/08 Fri 10/17/08 

330 Install Drywall 1 Side 1 wk Mon 10/20/08 Fri 10/24/08 

331 Install Wall Insulation 3 days Mon 10/27/08 Wed 10/29/08 

332 Rock Walls & Ceilings 1 wk Mon 10/27/08 Fri 10/31/08 

333 Tape and Finish Drywall 8 days Mon 10/27/08 Wed 11/5/08 

334 Install Aluminum Door & Window Frames 1 wk Thu 10/30/08 Wed 11/5/08 

335 Walls Construction Complete 0 days Wed 11/5/08 Wed 11/5/08 

336 Ceiling Construction 34 days Mon 10/20/08 Mon 12/8/08 

337 Install T-bar Ceiling 2 wks Thu 11/6/08 Wed 11/19/08 

338 Install Specialty Ceiling 1 wk Mon 10/20/08 Fri 10/24/08 

339 Install Light Fixtures 1 wk Thu 11/13/08 Wed 11/19/08 

4th Quarter 1st Quarter 2nd Quarter 3rd Quarter 4th Quarter 1st Quarter 2nd Quarter 3rd Quarter 4th Quart 

Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov 

6/17 Walls Construction Complete 
 Ceiling Construction 
 6/10 Install T-bar Ceiling

 7/16 Install Specialty Ceiling 
 6/10 Install Light Fixtures 
 6/10 Install
Registers 
 6/17 Trim Fire Sprinkler Heads 

6/17 Install Telephone/Data Cabling 
 6/23 Above Ceiling Fire Inspection 
 6/24 Above
Ceiling Building Inspection 
 6/25 Drop Ceiling Tiles 

Finishes 
 6/16 Paint Walls 
 6/24 Trim Out Elect/Data

 6/19 Install Open Office Carpet 
 6/26 Install Open Office Partitions/Hookup/Furniture 
 6/23 | Install Carpet Offices & Conference Rm. 
 6/25 | Install Doors & Hardware 
 BATHROOM
SHOWER CONSTRUCTION 
 6/23 Paint Walls and Ceilings 

6/24 1st Floor Bathroom Const Complete 
 7/2 Open Office Complete 
 7/3 City & Fire
Inspections 
 6/25 Startup & Balance Office AHU’s 

7/7 Temporary Certificate Of Occupancy for Office Area 

8/7 OK To Proceed With Phase 2 Construction 
 DEMO 
 8/8 Electrical Safe-Off 

8/20 Demo (E)T-Bar Ceiling 
 9/3 Strategic Mechanical Demo 
 9/11 Demo (E) Walls

 9/24 Misc. Demo Complete 
 Below Slab Plumbing & Electrical 
 8/8 Layout
Trenches 
 8/12 Locate Underground Utilities 

8/13 Saw cut and Remove Concrete 
 8/15 Excavate Trenches 
 8/19 Install Plumbing and
Electrical 
 8/25 Inspection 
 8/26 Backfill Trenches 
 8/28 Install Rebar

 8/29 Inspection 
 9/1 Patch Concrete 
 9/2 Below Slab Work Complete

 Overhead Rough-In 
 9/3 Modify Fire Sprinkler Piping 
 Rough In HVAC
Duct Work 
 9/11 Install Horizontal Duct mains & Branch lines 

9/25 Rough In HW Piping 
 9/25 Rough In Overhead Electric 
 9/29 Rough In
Tele-Com Data Cable Trays 
 10/3 Overhead Rough In Complete 

Wall Construction 
 10/6 Frame Full Height Walls ( Rated Walls & Coordinate With MEP) 
 10/13 In Wall MEP Rough In 
 10/17 Wall Inspection

 10/20 Install Drywall 1 Side 
 10/27 | Install Wail Insulation 
 10/27 | Rock
Walls & Ceilings 
 10/27 Tape and Finish Drywall 

10/30 Install Aluminum Door & Window Frames 

11/5 Walls Construction Complete 
 Ceiling Construction 
 11/6 Install T-bar Ceiling

 10/20 Install Specialty Ceiling 
 11/13 Install Light Fixtures 
 Page 5 Printed: Fri
3/7/08 

	
	

 XL CONSTRUCTION 
 DGA 
 AEI 

CRB 
 XL PROJECT No.: 3052 REVANCE THERAPEUTICS Issued: 03/5/08 Headquarters and Manufacturing Facility 
 NEWARK Proposed Construction Schedule 
 4th Quarter
1st Quarter 2nd Quarter 3rd Quarter 4th Quarter 1st Quarter 2nd Quarter 3rd Quarter 4th Quart 
 ID Task Name
Duration Start Finish Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov 
 340 Install Register’s 1 wk Thu 11/20/08 Wed 11/26/08 11/20 Install Registers 
 341 Trim Fire Sprinkler Heads 3 days Thu 11/20/08 Mon 11/24/08 11/20 Trim Fire Sprinkler Heads 
 342 Install Telephone/Data Cabling 1 wk Thu 11/20/08 Wed 11/26/08 11/20 Install Telephone/Data Cabling 
 343 Above Ceiling Fire Inspection 0 days Wed 11/26/08 Wed 11/26/08 11/26 Above Ceiling Fire Inspection 
 344 Above Ceiling Building Inspection 0 days Mon 12/1/08 Mon 12/1/08 12/1 Above Ceiling Building Inspection 
 345 Drop Ceiling Tiles 1 wk Tue 12/2/08 Mon 12/8/08 12/2 Drop Ceiling Tiles 
 346 Finishes 30 days Thu 11/6/08 Fri 12/19/08 Finishes 
 347 Paint Walls 2 wks Thu 11/6/08 Wed 11/19/08 11/6 Paint Walls 
 348 Trim Out Elect/Data 2 wks Thu 11/13/08 Wed 11/26/08 11/13 Trim Out Elect/Data 
 349 Install Open Office Carpet 1 wk Thu 11/20/08 Wed 11/26/08 11/20 Install Open Office Carpet 
 350 Install Open Office Partitions / Hookup / Furniture 2 wks Mon 12/1/08 Fri 12/12/08 12/1 Install Open Office Partitions / Hookup / Furniture 

351 Install Carpet Offices & Conference Rm. 1 wk Mon 12/8/08 Fri 12/12/08 12/8 Install Carpet Offices &
Conference Rm. 
 352 Install Doors & Hardware 1 wk Mon 12/15/08 Fri 12/19/08 12/15 Install
Doors & Hardware 
 353 BATHROOM & SHOWER CONSTRUCTION 5 days Thu 11/20/08 Wed 11/26/08
BATHROOM & SHOWER CONSTRUCTION 
 354 Remove Toilet/ Shower Partitions and Accessories 2 days Thu
11/20/08 Fri 11/21/08 11/20 | Remove Toilet/Shower Partitions and Accessories 
 355 Paint Walls and Ceilings 3
days Mon 11/24/08 Wed 11/26/08 11/24 | Paint Walls and Ceilings 
 356 Install Toilet/ Shower Partitions and
Accessories 2 days Mon 11/24/08 Tue 11/25/08 11/24 Install Toilet/Shower Partitions and Accessories 
 357 1st
Floor Bathroom Const Complete 0 days Tue 11/25/08 Tue 11/25/08 11/25 1st Floor Bathroom Const Complete 
 358
Open Office Complete 0 days Fri 12/19/08 Fri 12/19/08 12/19 Open Office Complete 
 359 City & Fire
Inspections 1 wk Mon 12/22/08 Fri 12/26/08 12/22 City & Fire Inspections 
 360 Startup &
Balance Office AHU’s 1 wk Tue 12/9/08 Mon 12/15/08 12/9 Startup & Balance Office AHU’s 
 361
Temporary Certificate Of Occupancy for Office Area 0 days Fri 12/26/08 Fri 12/26/08 12/26 Temporary Certificate Of Occupancy for Office Area 
 362 ASEPTIC & MANUFACTURING BUILDOUT 167 days Fri 8/8/08 Thu 4/2/09 ASEPTIC & MANUFACTURING BUILDOUT 

363 Overhead Rough-in 45 days Mon 10/6/08 Tue 12/9/08 Rough In HVAC Ductwork 

364 Rough In HVAC Ductwork 30 days Mon 10/6/08 Fri 11/14/08 Rough In HVAC Ductwork 

365 Vertical Raiser Duct @ Shafts 2 wks Mon 10/6/08 Fri 10/17/08 10/6 Vertical Raiser Duct @ Shafts 

366 Horizontal Duct Mains & Branch Duct Lines 4 wks Mon 10/20/08 Fri 11/14/08 10/20 Horizontal Duct
Mains & Branch Duct Lines 
 367 Rough In Overhead Electric 3 wks Mon 11/17/08 Tue 12/9/08 11/17 Rough
In Overhead Electric 
 368 Rough In Tele-Com Data 2 wks Mon 11/24/08 Tue 12/9/08 11/24 Rough In Tele-Com Data

 369 Modify Fire Sprinkler Piping (Remove @ new added beams / New 3 wks Mon 11/17/08 Tue 12/9/08 11/17 Modify
Fire Sprinkler Piping (Remove @ new added beams / New Drops) 
 Drops) 

370 Rough In Process Piping Mains 3 wks Mon 11/3/08 Fri 11/21/08 11/3 Rough In Process Piping Mains 

371 Over Head Rough In Complete 0 days Tue 12/9/08 Tue 12/9/08 12/9 Over Head Rough In Complete 

372 Below Slab Plumbing & Electrical 41 days Fri 8/8/08 Mon 10/6/08 Below Slab Plumbing & Electrical

 373 Layout Trenches 1 wk Fri 8/8/08 Thu 8/14/08 8/8 Layout Trenches 

374 Locate Underground Utilities 2 days Fri 8/15/08 Mon 8/18/08 8/15 | Locate Underground Utilities 

375 Saw cut and Remove Concrete 3 days Tue 8/19/08 Thu 8/21/08 8/19 | Saw cut and Remove Concrete 

376 Excavate Trenches 1 wk Fri 8/22/08 Thu 8/28/08 8/22 Excavate Trenches 

377 Remove Soil & Demo Existing Grade Beams & Coring 1 wk Fri 8/29/08 Thu 9/4/08 8/29 Remove
Soil & Demo Existing Grade Beams & Coring 
 378 Install Plumbing and Electrical 2 wks Fri
9/5/08 Fri 9/19/08 9/5 Install Plumbing and Electrical 
 379 Inspection 0 days Fri 9/19/08 Fri 9/19/08 9/19
Inspection 
 380 Backfill Trenches 1 wk Mon 9/22/08 Fri 9/26/08 9/22 Backfill Trenches 

381 Install Visqueen / Sand / Rebar 1 wk Mon 9/29/08 Fri 10/3/08 9/29 Install Visqueen / Sand / Rebar 

382 Inspection 0 days Fri 10/3/08 Fri 10/3/08 10/3 Inspection 

383 Patch / Pour Back Concrete 1 day Mon 10/6/08 Mon 10/6/08 10/6 Patch /Pour Back Concrete 

77 days 10/6 Patch / Pour Back Concrete 
 385 Early Wall Layout & Install Overhead High Wall Track 2 wks Tue 9/9/08 Mon 9/22/08 9/9 Early Wall Layout & Install Overhead High Wail Track 

386 Frame Ceiling High Walls (MEP Coordination Work Around) 8 days Mon 11/3/08 Wed 11/12/08 11/3 Frame Ceiling High Walls
(MEP Coordination Work Around) 
 387 Frame Walls ( Corridors ) 2 wks Mon 11/10/08 Fri 11/21/08 11/10 Frame Walls
( Corridors ) 
 388 Install Hollow Metal Door Frames & Window Frames 6 days Mon 11/10/08 Mon 11/17/08
11/10 Install Hollow Metal Door Frames & Window Frames 
 389 In Wall MEP Rough In 2 wks Mon 11/10/08
Fri 11/21/08 11/10 In Wall MEP Rough In 
 390 Install HM Welded Frames 3 days Thu 11/6/08 Mon 11/10/08 11/6
Install HM Welded Frames 
 391 Frame Corridor Ceiling 2 wks Mon 11/17/08 Tue 12/2/08 11/17 Frame Corridor
Ceiling 
 392 Wall Inspection 0 days Fri 11/21/08 Fri 11/21/08 11/21 Wall Inspection 

393 Install Drywall 1 Side Facing Open Areas 1 wk Mon 11/24/08 Tue 12/2/08 11/24 Install Drywall 1 Side Facing Open Areas

 394 Install Wall Insulation 4 days Mon 12/1/08 Thu 12/4/08 12/1 Install Wall Insulation 

395 Protocol Clean Track / Rock Walls & Ceilings 13 days Wed 12/3/08 Fri 12/19/08 12/3 Protocol Clean Track /
Rock Walls & Ceilings 
 396 Tape and Finish Drywall 2 wks Mon 12/15/08 Fri 12/26/08 12/15 Tape and
Finish Drywall 
 397 Walls Construction Complete 0 days Fri 12/26/08 Fri 12/26/08 12/26 Walls Construction
Complete 
 398 Gyp. Board Ceiling Construction 46 days Gyp. Board Ceiling Construction 

399 Frame Drywall Ceilings & Soffits 4 wks Mon 11/24/08 Tue 12/23/08 11/24 Frame Drywall Ceilings &
Soffits 
 400 Rough-In Lights 2 wks Wed 12/17/08 Tue 12/30/08 12/17 | Rough-In Lights 

401 Trim Fire Sprinkler Heads 4 days Wed 12/24/08 Mon 12/29/08 12/24 Trim Fire Sprinkler Heads 

402 Above Ceiling Fire Inspection 0 days Tue 12/30/08 Tue 12/30/08 12/30 Above Ceiling Fire Inspection 

403 Above Ceiling Building Inspection 0 days Tue 12/30/08 Tue 12/30/08 12/30 Above Ceiling Building Inspection 

404 Drywall Soffits and Ceilings 2 wks Wed 12/31/08 Tue 1/13/09 12/31 Drywall Soffits and Ceilings 

405 Tape Soffits and Ceilings 8 days Wed 1/14/09 Fri 1/23/09 1/14 Tape Soffits and Ceilings 

406 Trim Out Elect and Sprinklers 3 days Mon 1/26/09 Wed 1/28/09 1/26 | Trim Out Elect and Sprinklers 

407 Finishes 32 days Mon 1/26/09 Tue 3/10/09 Finishes 

Page 6 Printed: Fri 3/7/08 

	
	

 XL CONSTRUCTION 
 DGA 
 AEI 

CRB 
 XL PROJECT No.: 3052 
 REVANCE THERAPEUTICS
Headquarters and Manufacturing Facility 
 NEWARK Proposed Construction Schedule 

Issued: 03/5/08 
 ID Task Name Duration Start Finish 
 408 Paint
Walls (Epoxy Finish) 3 wks Mon 1/26/09 Fri 2/13/09 
 409 Doors & Hardware 2 wks Mon 2/16/09 Fri 2/27/09

 410 Install Vinyl Flooring 2 wks Mon 2/16/09 Fri 2/27/09 

411 Install Lab Equip. & Casework 2 wks Mon 2/23/09 Fri 3/6/09 

412 Trim Out Elec./ Data 2 wks Wed 2/25/09 Tue 3/10/09 

413 Install Signage 4 days Thu 2/12/09 Tue 2/17/09 

414 T-bar Ceiling Construction 16 days Mon 2/16/09 Mon 3/9/09 

415 Install T-bar Ceiling Open Areas 1 wk Mon 2/16/09 Fri 2/20/09 

416 Install Light Fixtures 5 days Mon 2/16/09 Fri 2/20/09 

417 Install Registers 1 wk Mon 2/23/09 Fri 2/27/09 

418 Trim Fire Sprinkler Heads 1 wk Mon 2/23/09 Fri 2/27/09 

419 Install Telephone/Data Cabling 1 wk Mon 2/23/09 Fri 2/27/09 

420 Above Ceiling Fire Inspection 0 days Fri 2/27/09 Fri 2/27/09 

421 Above Ceiling Building Inspection 0 days Mon 3/2/09 Mon 3/2/09 

422 Drop Ceiling Tiles 1 wk Tue 3/3/09 Mon 3/9/09 
 423 Area Fill/Lyo/Capping 20 days Fri 3/6/09 Thu 4/2/09 
 424 Install Clean Wall System 2 wks Fri 3/6/09 Thu 3/19/09 
 425 Install Stainless Pass Thru 5 days Fri 3/20/09 Thu 3/26/09 
 426 Install Manufacturing Equipment 5 days Fri 3/27/09 Thu 4/2/09 
 427 1st Floor Manufacturing Area Complete 0 days Fri 3/6/09 Fri 3/6/09 
 428 Level 2 Protocol Begins 0 days Fri 3/6/09 Fri 3/6/09 
 429 Area 2- Wash Area/ Gown & Clean Equipment Staging 19 days Mon 3/9/09 Thu 4/2/09 
 430 Install GMP Autoclave 1 wk Mon 3/9/09 Fri 3/13/09 
 431 Install Stainless Pass Thrus 5 days Mon 3/16/09 Fri 3/20/09 
 432 Install Glass Wash Equipment 1 wk Mon 3/23/09 Fri 3/27/09 
 433 Install Scullery Sink & Stainless Equipment 4 days Mon 3/30/09 Thu 4/2/09 
 434 MECHANICAL ROOM CONSTRUCTION BUILD-OUT 90 days Thu 11/6/08 Fri 3/13/09 
 435 Mechanical Room Construction 30 days Thu 11/6/08 Fri 12/19/08 
 436 Frame Full Height Wall 4 days Thu 11/6/08 Tue 11/11/08 
 437 Install Hollow Metal Door Frames 2 days Fri 11/7/08 Mon 11/10/08 
 438 In Wall MEP Rough In 1 wk Wed 11/12/08 Tue 11/18/08 
 439 Wall Inspection 0 days Tue 11/18/08 Tue 11/18/08 
 440 Install Drywall 1 Side Facing Open Areas 1 wk Wed 11/19/08 Tue 11/25/08 
 441 Install Wall Insulation 1 day Wed 11/26/08 Wed 11/26/08 
 442 Rock Walls & Ceilings 5 days Wed 11/26/08 Thu 12/4/08 
 443 Tape and Finish Drywall 8 days Wed 11/26/08 Tue 12/9/08 
 444 Paint Interior Wall 3 days Wed 12/10/08 Fri 12/12/08 
 445 Install Lighting Fixtures 5 days Mon 12/15/08 Fri 12/19/08 
 446 Mechanical Equipment Installation 68 days Wed 12/10/08 Fri 3/13/09 
 447 UPS Room 68 days Wed 12/10/08 Fri 3/13/09 
 448
Install Epoxy Flr. System 5 days Wed 12/10/08 Tue 12/16/08 
 449 Install Battery Racks & UPS Controls /
Battery Monitoring 3 wks Wed 12/17/08 Tue 1/6/09 
 450 Install Room Finishes & life Safety
Controls & Testing 2 wks Wed 1/7/09 Tue 1/20/09 
 451 Level 2 Protocol 0 days Fri 3/6/09 Fri 3/6/09

 452 Testing UPS System 5 days Mon 3/9/09 Fri 3/13/09 

453 Install High Purity Water System 20 days Fri 1/16/09 Thu 2/12/09 

454 Install High Purity Skid & Piping 3 wks Fri 1/16/09 Thu 2/5/09 

455 Install High Purity Water Storage Tank & Piping 1 wk Fri 2/6/09 Thu 2/12/09 

456 Pure Steam Generator 23 days Fri 1/30/09 Tue 3/3/09 

457 Install Steam Generator Skid 4 wks Fri 1/30/09 Thu 2/26/09 

458 Install WFI Storage Tank & Piping 8 days Fri 2/20/09 Tue 3/3/09 

459 WAREHOUSE & SHIPPING / RECEIVING 30 days Tue 11/11/08 Wed 12/24/08 

460 Warehouse/Shipping Construction 25 days Tue 11/11/08 Wed 12/17/08 

461 Frame Full Height Wall 3 days Tue 11/11/08 Thu 11/13/08 

462 Install Hollow Metal Door Frames 1 day Tue 11/11/08 Tue 11/11/08 

463 In Wall MEP Rough In 1 wk Wed 11/12/08 Tue 11/18/08 

464 Wall Inspection 0 days Tue 11/18/08 Tue 11/18/08 

465 Install Drywall 1 Side Facing Open Areas 1 wk Wed 11/19/08 Tue 11/25/08 

466 Install Wall Insulation 1 day Wed 11/26/08 Wed 11/26/08 

467 Rock Walls & Ceilings 5 days Wed 11/26/08 Thu 12/4/08 

468 Tape and Finish Drywall 8 days Wed 11/26/08 Tue 12/9/08 

469 Paint Interior Wall 3 days Wed 12/10/08 Fri 12/12/08 

470 Install Hung Lighting Fixtures 3 days Mon 12/15/08 Wed 12/17/08 

471 High Bay Storage Racks 5 days Thu 12/18/08 Wed 12/24/08 

472 Layout Storage Racks & Install 1 wk Thu 12/18/08 Wed 12/24/08 

473 ROOF CONSTRUCTION 35 days Mon 11/3/08 Tue 12/23/08 

474 Install GMP AHU’s 2 wks Mon 11/24/08 Tue 12/9/08 

4th Quarter 1st Quarter 2nd Quarter 3rd Quarter 4th Quarter 1st Quarter 2nd Quarter 3rd Quarter 4th Quart 

Oct Nov Dec Jan Feb Mar Apr May Jun July Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov 

1/26 Paint Walls (Epoxy Finish) 
 2/16 Doors & Hardware 
 2/16 Install Vinyl
Flooring 
 2/23 Install Lab Equip. & Casework 

2/25 Trim Out Elec./ Data 
 2/12 Install Signage 
 T-bar Ceiling Construction

 2/16 Install T-bar Ceiling Open Areas 
 2/16 Install Light Fixtures 
 2/23 Install
Registers 
 2/23 Trim Fire Sprinkler Heads 

2/23 Install Telephone/Data Cabling 
 2/27 Above Ceiling Fire Inspection 
 3/2 Above
Ceiling Building Inspection 
 3/3 DroP Ceiling Tiles 

Area Fill/Lyo/Capping 
 3/6 Install Clean Wall System 
 3/20 Install
Stainless Pass Thru 
 3/27 Install Manufacturing Equipment 

3/6 1st Floor Manufacturing Area Complete 
 3/6 Level 2 Protocol Begins 
 Area 2- Wash Area/
Gown & Clean Equipment Staging 
 3/9 Install GMP Autoclave 

3/16 Install Stainless Pass Thrus 
 3/23 Install Glass Wash Equipment 
 3/30 Install
Scullery Sink & Stainless Equipment 
 MECHANICAL ROOM CONSTRUCTION BUILD-OUT 

Mechanical Room Construction 
 11/6 Frame Full Height Wall 
 11/7 Install Hollow
Metal Door Frames 
 11/12 In Wall MEP Rough In 

11/18 Wall Inspection 
 11/19 Install Drywall 1 Side Facing Open Areas 

11/26 | Install Wall Insulation 
 11/26 Rock Walls & Ceilings 
 11/26 Tape
and Finish Drywall 
 12/10 | Paint Interior Wall 

12/15 Install Lighting Fixtures 
 UPS Room 
 12/10 Install Epoxy Flr. System

 12/17 Install Battery Racks & UPS Controls / Battery Monitoring 

1/7 Install Room Finishes & life Safety Controls & Testing 

3/6 Level 2 Protocol 
 3/9 Testing UPS System 
 Install High Purity Water
System 
 1/16 Install High Purity Skid & Piping 

2/6 Install High Purity Water Storage Tank & Piping 

Pure Steam Generator 
 1/30 Install Steam Generator Skid 
 2/20 Install
WFI Storage Tank & Piping 
 WAREHOUSE & SHIPPING / RECEIVING 

Warehouse / Shipping Construction 
 11/11 Frame Full Height Wall 
 11/11 | Install
Hollow Metal Door Frames 
 11/12 In Wall MEP Rough In 

11/18 Wall Inspection 
 11/19 Install Drywall 1 Side Facing Open Areas 

11/26 Install Wall Insulation 
 11/26 Rock Walls & Ceilings 
 11/26 Tape
and Finish Drywall 
 12/10 | Paint Interior Wall 

12/15 | Install Hung Lighting Fixtures 
 High Bay Storage Racks 
 12/18 Layout Storage
Racks & Install 
 ROOF CONSTRUCTION 

11/24 Install GMP AHU’s 
 Page 7 Printed: Fri 3/7/08 

	
	

 XL CONSTRUCTION 
 DGA 
 AEI 

CRB 
 XL PROJECT No.: 3052 
 REVANCE THERAPEUTICS
Headquarters and Manufacturing Facility NEWARK Proposed Construction Schedule 
 Issued: 03/5/08 

ID Task Name 
 Duration Start Finish 
 475 Penthouse Area
Construction 35 days Mon 11/3/08 Tue 12/23/08 
 476 Install Chiller Pads 3 wks Mon 11/3/08 Fri 11/21/08

 477 Install Chiller / Piping 4 wks Mon 11/24/08 Tue 12/23/08 

478 EQUIPMENT START UP AND COMMISSIONING 59 days Tue 3/10/09 Fri 5/29/09 

479 M.E.P. COMMISSIONING 59 days Tue 3/10/09 Fri 5/29/09 

480 Air Balance Office 2 wks Tue 3/10/09 Mon 3/23/09 

481 Water Balance System 2 wks Mon 4/20/09 Fri 5/1/09 

482 Air Balance Controlled HVAC Areas (GMP Controlled Areas) 3 wks Mon 5/4/09 Fri 5/22/09 

483 System Trending 2 wks Mon 5/18/09 Fri 5/29/09 
 484 Air Monitor Bio Safety Cabinets Testing 1 wk Mon 5/25/09 Fri 5/29/09 
 485 Start Up Lab & Manufacturing Equipment 2 wks Fri 4/3/09 Thu 4/16/09 
 486 HVAC EQUIPMENT START UP 24 days Fri 4/3/09 Wed 5/6/09 
 487 Protocol 2 - Wipe Down Ail Areas 3 days Fri 4/3/09 Tue 4/7/09 
 488 Start Up AHU’s GMP Areas 1 wk Wed 4/8/09 Tue 4/14/09 
 489 Start Up Chilled Water 3 days Wed 4/15/09 Fri 4/17/09 
 490 Start Plant Steam Boiler 3 days Mon 4/20/09 Wed 4/22/09 
 491 Start Up Generator & Systems Testing 2 wks Thu 4/23/09 Wed 5/6/09 
 492 PROCESS EQUIPMENT START UP 30 days Mon 4/20/09 Fri 5/29/09 
 493 Pure Water Skid 2 wks Mon 4/20/09 Fri 5/1/09 

494 Pure Steam Generator 2 wks Mon 5/4/09 Fri 5/15/09 

495 WFI System 2 wks Mon 5/18/09 Fri 5/29/09 
 496 FINAL INSPECTIONS 54 days Thu 4/2/09 Wed 6/17/09 
 497 Construction Complete 0 days Thu 4/2/09 Thu 4/2/09 
 498 Fire Life Safety Inspections 1 wk Mon 5/18/09 Fri 5/22/09 
 499 Owner / Architecture Building Sign Off & Verification 1 wk Mon 5/25/09 Fri 5/29/09 
 500 Fire Final 3 wks Mon 5/25/09 Fri 6/12/09 
 501
Building Final 3 days Mon 6/15/09 Wed 6/17/09 
 502 REVANCE THERAPEUTICS OCCUPANCY 0 days Wed 6/17/09 Wed
6/17/09 
 4th Quarter 1st Quarter 2nd Quarter 3rd Quarter 4th Quarter 1st Quarter 2nd Quarter 3rd Quarter 4th
Quart 
 Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov

 Penthouse Area Construction 
 11/3 Install Chiller Pads 
 11/24 Install Chiller /
Piping 
 EQUIPMENT START UP AND COMMISSIONING 

M.E.P. COMMISSIONING 
 3/10 Air Balance Office 
 4/20 Water Balance System

 5/4 Air Balance Controlled HVAC Areas (GMP Controlled 

5/18 pm System Trending 
 5/25 Air Monitor Bio Safety Cabinets Testing 
 4/3
Start Up Lab & Manufacturing Equipment 
 HVAC EQUIPMENT START UP 

4/3 Protocol 2—Wipe Down All Areas 
 4/8 Startup AHU’s GMP Areas 
 4/15 Start Up
Chilled Water 
 4/20 Start Plant Steam Boiler 

4/23 Start Up Generator & Systems Testing 

PROCESS EQUIPMENT START UP 
 4/20 Pure Water Skid 
 5/4 Pure Steam Generator

 5/18 WFI System 
 FINAL INSPECTIONS 
 4/2 Construction Complete

 5/18 Fire Life Safety Inspections 
 5/25 Owner / Architecture Building Sign Off & Verification 
 5/25 Fire Final 
 6/15 Building Final 

6/17 REVANCE THERAPEUTICS OCCUPANCY 
 Page 8 
 Printed: Fri 3/7/08 

 ATTACHMENT 2 TO EXHIBIT B 

MEP ENGINEER’S SCOPE OF WORK 
 The following is the preliminary scope of the work for which mechanical, plumbing, process utility, electrical and fire protection engineering services will be provided. A detailed scope of work will be
developed during the design phases. 
  

	1)	Mechanical (HVAC) Systems 

 The
mechanical scope of work shall include but is not necessarily limited to: 
  

	 	•	 	 Conditioned air ventilation systems. 

  

	 	•	 	 Chilled water and heating hot water generation plant(s). Integration of existing chilled water plant 

 

	 	•	 	 Chilled water connection to equipment 

  

	 	•	 	 Building chilled water and heating hot water distribution systems. 

 

	 	•	 	 Air handling equipment and distribution systems. Integration of existing equipment. 

 

	 	•	 	 Supply air filtration. 

  

	 	•	 	 Exhaust air ventilation systems. 

  

	 	•	 	 General exhaust. 

  

	 	•	 	 Laboratory fume exhaust, including hoods, exhausted enclosures and snorkel exhaust. 

 

	 	•	 	 General and laboratory fume exhaust equipment and distribution systems. 

 

	 	•	 	 Process exhaust. 

  

	 	•	 	 Exhaust air filtration. 

  

	 	•	 	 Building Management and Control Systems. (BMS) 

  

	 	•	 	 HVAC equipment. 

  

	 	•	 	 Coordination with lighting control system. 

  

	 	•	 	 Integration of existing BMS, non validated system 

  

	 	•	 	 Design of GMP specific BMS, validated system 

  

	 	•	 	 Coordination with process utility control 

  

	 	•	 	 Plant Steam 

  

	 	•	 	 Plant steam generation equipment and distribution 

  

	 	•	 	 Plant steam connections to equipment. 

  

	2)	Plumbing Systems 

 The plumbing
scope of work shall include but is not necessarily limited to: 
  

	 	•	 	 Waste systems. 

  

	 	•	 	 Review of existing sanitary sewer systems within building. Expansion as necessary for Tenant’s requirements 

 

	 	•	 	 Laboratory and process waste systems within building and to sampling station located outside building. 

 

	 	•	 	 Laboratory and process waste sampling station(s)/hold tank(s) and potentially neutralization system. 

 

	 	•	 	 Storm drain system. 

  

	 	•	 	 Modification of existing systems for new work within the building. 

 

	 	•	 	 Natural Gas. 

  

	 	•	 	 Natural gas equipment and distribution from the building(s) meter. 

 

	 	•	 	 Distribution of natural gas for equipment and process use. 

 

	 	•	 	 Natural gas upgrade coordination with PG&E 

  

	 	•	 	 Domestic Water. 

  

	 	•	 	 Integrate existing domestic water systems within building and expand as necessary for Tenant’s requirements 

 

	 	•	 	 Integrate existing domestic hot water heating equipment. 

 

	 	•	 	 Cold and hot water distribution equipment and piping. 

 

	 	•	 	 Tempered water systems for emergency showers and eyewashes. 

  
 B-2-1

	 	•	 	 Industrial Water. 

  

	 	•	 	 Industrial water for laboratory use within building. 

  

	 	•	 	 Backflow prevention devices. 

  

	 	•	 	 Industrial hot water heating equipment. 

  

	 	•	 	 Industrial cold and hot water distribution equipment and piping. 

 

	 	•	 	 Connections to designated laboratory and process support equipment. 

 

	 	•	 	 Miscellaneous. 

	 	•	 	 Fuel systems for emergency power generation systems. 

 

	3)	Process Utility Systems 

 The
process utility systems scope of work shall include but is not necessarily limited to: 
  

	 	•	 	 Purified Water. 

  

	 	•	 	 USP Purified Water for use within Manufacturing and laboratory areas. 

 

	 	•	 	 Points of use include the suites with in the manufacturing facility, the QC Labs and the R&D Labs, the Clean Steam Skid, the WFI skid and process
equipment 

  

	 	•	 	 Booster pump for city water pressure, filtration and treatment equipment. 

 

	 	•	 	 Storage and distribution equipment and piping. 

  

	 	•	 	 System monitoring and controls. 

  

	 	•	 	 Prepare pre-purchase package 

  

	 	•	 	 WFI 

  

	 	•	 	 WFI for use within the Manufacturing plant. 

  

	 	•	 	 Points of use include the suites with in the manufacturing facility and process equipment 

 

	 	•	 	 Distribution equipment and piping. 

  

	 	•	 	 System monitoring and controls. 

  

	 	•	 	 Prepare pre-purchase package. 

  

	 	•	 	 Clean Steam. 

  

	 	•	 	 Clean steam for process equipment. 

  

	 	•	 	 Points of use include process equipment and the fermentation skid 

 

	 	•	 	 Distribution equipment and piping. 

  

	 	•	 	 System monitoring and controls. 

  

	 	•	 	 Prepare pre-purchase package. 

  

	 	•	 	 CDA. 

  

	 	•	 	 CDA will be distributed to the Manufacturing and laboratory areas from a central generation skid. 

 

	 	•	 	 Preliminary points of use include suites within the manufacturing facility, the QC Labs and the R&D Labs, instrument air, and process equipment.

  

	 	•	 	 Storage and distribution equipment and piping. 

  

	 	•	 	 System monitoring and controls. 

  

	 	•	 	 Nitrogen. 

  

	 	•	 	 Nitrogen will be distributed to the Manufacturing and laboratory areas from a mini-bulk tank. 

 

	 	•	 	 Preliminary points of use include suites within the manufacturing facility, the QC Labs and the R&D Labs. 

 

	 	•	 	 Storage and distribution equipment and piping. 

  

	 	•	 	 System monitoring and controls. 

  

	 	•	 	 Vacuum. 

  

	 	•	 	 Vacuum will be distributed to the Manufacturing and laboratory areas from a central generation skid. 

 

	 	•	 	 Preliminary points of use include suites within the manufacturing facility, the QC Labs and the R&D Labs, and process equipment.

  

	 	•	 	 Storage and distribution equipment and piping. 

  

	 	•	 	 System monitoring and controls. 

  
 B-2-2

	 	•	 	 Process Heating and Cooling Water. 

  

	 	•	 	 Process heating and cooling water will be provided to the jackets of the fermentation vessels. 

 

	 	•	 	 The process heating and cooling water will be provided by a remote re-circulating unit with heating and cooling capabilities.

  

	 	•	 	 Distribution equipment and piping. 

  

	 	•	 	 System monitoring and controls. 

  

	 	•	 	 Laboratory and Process Gases. 

  

	 	•	 	 Laboratory and process vacuum systems, including equipment, distribution to bench and connection to designated equipment. 

 

	 	•	 	 Laboratory and process compressed dry air systems, including equipment, distribution to bench and connection to designated equipment.

  

	 	•	 	 Laboratory and process specialty gas systems, including carbon dioxide, nitrogen, liquid nitrogen. Gas manifolds, distribution and connection to
selected bench and/or designated equipment. 

  

	4)	Fire Protection Systems. 

 The
Fire Protection scope of work shall include but is not necessarily limited to: 
  

	 	•	 	 Integration of existing fire sprinkler infrastructure 

 

	 	•	 	 Fire main modification from site water source as necessary. 

 

	 	•	 	 Fire riser and automatic sprinkler system within building. 

 

	 	•	 	 Pre-action systems at designated locations. 

  

	 	•	 	 Alternative fire protection systems at designated locations. 

 

	5)	Electrical Systems. 

 The
Electrical scope of work shall include but is not necessarily limited to: 
  

	 	•	 	 Power Systems 

  

	 	•	 	 Main electrical service, including primary service, service transformer and main switchgear. 

 

	 	•	 	 Power distribution systems, including secondary transformers and distribution panels. 

 

	 	•	 	 Power raceways, wiring, boxes, and devices. 

  

	 	•	 	 Power for designated equipment. 

  

	 	•	 	 Emergency and Standby power systems. 

  

	 	•	 	 Integration of existing emergency generator and transfer switch. Expansion as necessary 

 

	 	•	 	 Emergency power distribution systems, including secondary transformers and distribution panels. 

 

	 	•	 	 Uninterruptible power systems. 

  

	 	•	 	 Prepare pre-purchase package. 

  

	 	•	 	 Grounding Systems. 

  

	 	•	 	 Building and equipment grounding systems. 

  

	 	•	 	 Lighting Systems. 

  

	 	•	 	 Site lighting at equipment yards. 

  

	 	•	 	 Interior and exterior building lighting. 

  

	 	•	 	 Power distribution for lighting systems. 

  

	 	•	 	 Lighting control systems. 

  

	 	•	 	 Special Systems. 

  

	 	•	 	 Expansion of existing fire alarm system, including manual systems and smoke detection. 

 

	 	•	 	 Telephone cable trays, raceways and device boxes. 

  

	 	•	 	 Data cable trays, raceways and device boxes. 

  

	 	•	 	 Security system raceways and device boxes. 

 SCOPE OF SERVICES 

  
 B-2-3

 The following scope of services is required for the scope of the work delivered by the design/bid method.
The services will be provided from Basis of Design through Commissioning and Qualification phases. 
 Basis of Design Phase 

 

	1)	General 

  

	 	•	 	 Perform preliminary site investigation. 

  

	 	•	 	 Participate in weekly design meetings. 

  

	 	•	 	 Prepare Basis of Design report describing the preliminary criteria and concept for each system and identifying any unresolved issues.

  

	 	•	 	 Provide input and review cost estimate prepared by others. 

 

	2)	Mechanical Systems 

  

	 	•	 	 Identify mechanical systems. 

  

	 	•	 	 Develop design criteria for each system. 

  

	 	•	 	 Identify system flexibility and redundancy issues. 

  

	 	•	 	 Develop alternative system concepts for discussion & evaluation. 

 

	 	•	 	 Preliminary layouts including space allocations for equipment, ductwork, locations for equipment, etc. 

 

	3)	Plumbing Systems 

  

	 	•	 	 Identify plumbing systems. 

  

	 	•	 	 Develop design criteria for each system. 

  

	 	•	 	 Identify system flexibility and redundancy issues. 

  

	 	•	 	 Develop alternative system concepts for discussion & evaluation. 

 

	 	•	 	 Preliminary layouts including space allocations for equipment, piping, locations for equipment, etc. 

 

	4)	Process Utility Systems 

  

	 	•	 	 Identify process utility systems. 

  

	 	•	 	 Develop design criteria for each system. 

  

	 	•	 	 Identify system flexibility and redundancy issues. 

  

	 	•	 	 Develop alternative system concepts for discussion & evaluation. 

 

	 	•	 	 Preliminary layouts including space allocations for equipment, piping, locations for equipment, etc. 

 

	5)	Fire Protection Systems 

  

	 	•	 	 Identify site fire main capacity. 

  

	 	•	 	 Develop design criteria including identification of insurance underwriter’s requirements 

Identify special fire protection system requirements, including pre-action, FM-200, etc 

 

	4)	Electrical Systems 

  

	 	•	 	 Identify electrical power, lighting and special systems. Integrate existing infrastructure 

 

	 	•	 	 Develop general design criteria for each electrical system. 

 

	 	•	 	 Identify system flexibility and redundancy issues. 

  

	 	•	 	 Develop alternative system concepts for discussion & evaluation. 

 

	 	•	 	 Develop preliminary power load study. 

  

	 	•	 	 Preliminary layouts including space allocations for site and building equipment and distribution. 

Preliminary Design Phase 
  

	1)	General 

  

	 	•	 	 Perform detailed site investigation. 

  

	 	•	 	 Attend weekly design meetings. 

  
 B-2-4

	 	•	 	 Prepare report documenting major decisions related to the mechanical, electrical and plumbing systems. 

 

	 	•	 	 Perform detailed code analysis. 

  

	 	•	 	 Coordinate acoustical and vibration criteria with acoustical/vibration consultant 

 

	 	•	 	 Coordinate equipment vendors and concepts with subcontractors. 

 

	 	•	 	 Coordinate equipment power requirements – normal and emergency. 

 

	 	•	 	 Coordinate equipment weights with structural consultant. 

 

	 	•	 	 Coordinate equipment gas, water, and waste requirements. Prepare and submit required documentation for utility company service requests

  

	 	•	 	 Provide input and review cost estimate prepared by the General Contractor. 

 

	2)	Mechanical Systems 

  

	 	•	 	 Finalize design criteria. 

  

	 	•	 	 Finalize system selection. 

  

	 	•	 	 Prepare preliminary building load calculations. 

  

	 	•	 	 Prepare preliminary equipment list. 

  

	 	•	 	 Develop preliminary equipment layouts and major distribution concepts including vent shafts, air handler and exhaust fan locations.

  

	 	•	 	 Coordinate chilled water and steam system requirements and process utility requirements. 

 

	 	•	 	 Develop facility special requirements 

  

	 	•	 	 Update calculations and equipment lists prepared in previous phase 

 

	 	•	 	 Prepare preliminary equipment energy calculations 

  

	 	•	 	 Develop preliminary system airflow diagrams 

  

	 	•	 	 Develop preliminary control diagrams 

  

	 	•	 	 Finalize major equipment size and locations 

  

	 	•	 	 Identify major penetrations, plenums and ducts 

  

	 	•	 	 Finalize building zoning 

  

	 	•	 	 Develop major duct and pipe routing and typical distribution concepts 

 

	 	•	 	 Prepare preliminary specifications. 

  

	3)	Plumbing Systems 

  

	 	•	 	 Finalize design criteria. 

  

	 	•	 	 Finalize system selection. 

  

	 	•	 	 Prepare preliminary system load/capacity calculations for plumbing systems. 

 

	 	•	 	 Prepare preliminary equipment list. 

  

	 	•	 	 Develop preliminary equipment layouts and major distribution concepts. 

 

	 	•	 	 Coordinate preliminary roof drainage locations with the architect. 

 

	 	•	 	 Coordinate site gas, water, and sewer requirements, including tie-ins, meter location, etc. 

 

	 	•	 	 Update calculations and equipment lists prepared in previous phase 

 

	 	•	 	 Finalize major equipment size and locations 

  

	 	•	 	 Develop preliminary plumbing fixture lists. 

  

	 	•	 	 Develop system flow diagrams. 

  

	 	•	 	 Develop major pipe routing and typical distribution concepts 

 

	 	•	 	 Prepare preliminary specifications. 

  

	4)	Process Utility Systems 

  

	 	•	 	 Finalize design criteria. 

  

	 	•	 	 Finalize system selection. 

  

	 	•	 	 Prepare preliminary system load/capacity calculations for process utility systems. 

 

	 	•	 	 Prepare preliminary equipment list. 

  

	 	•	 	 Develop preliminary equipment layouts and major distribution concepts. 

 

	 	•	 	 Coordinate plant steam and condensate requirements with mechanical engineer, including loads and capacities, tie-ins, valve and metering requirements,
etc. 

  

	 	•	 	 Coordinate industrial water and waster requirements with plumbing engineer, including loads and capacities, tie-ins, valves and metering requirements,
etc. 

  

	5)	Fire Protection Systems 

  
 B-2-5

	 	•	 	 Finalize design criteria. 

  

	 	•	 	 Finalize riser and main locations. 

  

	6)	Electrical Systems 

  

	 	•	 	 Finalize design criteria. 

  

	 	•	 	 Prepare preliminary building load calculations. 

  

	 	•	 	 Coordinate main power service with utility company. 

  

	 	•	 	 Coordinate telecommunications service requirements with Tenant’s selected vendor 

 

	 	•	 	 Develop preliminary equipment layouts and major distribution concepts including main electrical room, data closets, etc 

 

	 	•	 	 Prepare schematic single line or riser diagrams for power and special systems 

Detailed Design/ Construction Package Phase 
  

	1)	General 

  

	 	•	 	 Develop the design for inter-discipline coordination. 

 

	 	•	 	 Prepare documentation adequate for obtaining a building and specialty permits from the authorities have jurisdiction. 

 

	 	•	 	 Prepare documentation adequate for the bidding and construction of the work. 

 

	2)	Mechanical Systems 

  

	 	•	 	 Update calculations and equipment lists prepared under previous phase. 

 

	 	•	 	 Prepare final equipment energy calculations. 

  

	 	•	 	 Prepare final system airflow diagrams. 

  

	 	•	 	 Prepare final control diagrams 

  

	 	•	 	 Prepare final specifications. 

  

	 	•	 	 Finalize major equipment size and locations. 

  

	 	•	 	 Finalize major penetrations, plenums and ducts 

  

	 	•	 	 Finalize building zoning 

  

	 	•	 	 Finalize major duct and pipe routing and distributions 

 

	 	•	 	 Coordinate the mechanical work with the work of other disciplines. 

 

	 	•	 	 Submit final calculations and equipment lists. 

  

	 	•	 	 Prepare construction documents for the mechanical work, including calculations, drawings and specifications, required for the permitting and bidding of
the work. 

  

	3)	Plumbing Systems 

  

	 	•	 	 Update calculations and equipment lists prepared under previous phase. 

 

	 	•	 	 Finalize major equipment size and locations. 

  

	 	•	 	 Prepare final plumbing fixture list. 

  

	 	•	 	 Prepare final system flow diagrams. 

  

	 	•	 	 Prepare final specifications. 

  

	 	•	 	 Finalize major pipe routing and distributions, including riser diagrams 

 

	 	•	 	 Coordinate the plumbing work with the work of other disciplines. 

 

	 	•	 	 Submit final calculations and equipment lists. 

  

	 	•	 	 Prepare construction documents for the mechanical work, including calculations, drawings and specifications, required for the permitting and bidding of
the work. 

  

	4)	Process Utility Systems 

  

	 	•	 	 Update calculations and equipment lists prepared under previous phase. 

 

	 	•	 	 Prepare final specifications. 

  

	 	•	 	 Finalize major equipment size and locations. 

  

	 	•	 	 Prepare system flow diagrams 

  

	 	•	 	 Finalize major pipe routings and typical distribution. 

 

	 	•	 	 Coordinate the process utility work with the work of other disciplines. 

 

	 	•	 	 Submit final calculations and equipment lists. 

  

	 	•	 	 Prepare construction documents for the process utility work, including calculations, drawings and specifications, required for the permitting and
bidding of the work. 

  
 B-2-6

	5)	Fire Protection Systems 

  

	 	•	 	 Finalize fire protection approach and complete layout 

 

	 	•	 	 Prepare fire protection zoning diagrams. 

  

	 	•	 	 Prepare performance specifications. 

  

	6)	Electrical Systems 

  

	 	•	 	 Update calculations, diagrams and equipment lists prepared under previous phase. 

 

	 	•	 	 Finalize layout of main power service and coordinate with utility company 

 

	 	•	 	 Finalize power distribution concepts including distribution panel locations, device type and locations 

 

	 	•	 	 Define emergency power and UPS power requirements 

  

	 	•	 	 Prepare lighting fixture selection and lighting layouts. 

 

	 	•	 	 Prepare fire alarm system layouts and coordinate with mechanical systems 

 

	 	•	 	 Coordinate security, telecommunications and data locations and raceway requirements with Tenant’s vendors 

 

	 	•	 	 Security to be on separate plans, controlled 

  

	 	•	 	 Prepare final specifications. 

  

	 	•	 	 Finalize major equipment size and locations. 

  

	 	•	 	 Finalize major duct and pipe routing and distributions 

 

	 	•	 	 Coordinate the electrical work with the work of other disciplines. 

 

	 	•	 	 Submit final calculations and equipment lists. 

  

	 	•	 	 Prepare construction documents for the electrical work, including calculations, drawings and specifications, required for the permitting and bidding of
the work. 

 Bidding and Permitting Phase 

 

	1)	General 

  

	 	•	 	 Review with and advise General Contractor on subcontractor bids. 

 

	 	•	 	 Attend meetings to review General Contractor’s Guaranteed Maximum Price. 

 

	 	•	 	 Participate in the bidding process, answer bid questions, review responses for completeness, compliance to specification and best value

 Construction Phase 
  

	1)	General 

  

	 	•	 	 Attend weekly coordination meetings, thru the completion of the construction phase. 

 

	 	•	 	 Perform field observations on a regular basis. 

  

	 	•	 	 Timely response to RFIs. 

  

	 	•	 	 Review of submittals. 

  

	 	•	 	 Perform final punch list inspection(s). 

 Closeout Phase 
  

	 	•	 	 Provide record AutoCAD drawings based upon as-built information received from the General Contractor and system vendors – two sets will be
required, one to incorporate the record set from the contractor, the second post qualification activities. Provide drawings in PDFs and AutoCAD formats (electronic). 

 Extended Services required for scope of work serving the GMP areas: 
  

	1)	Basis of Design Phase 

  

	 	•	 	 Development and documentation user requirement specification (URS), including performance criteria and capacities. 

 

	 	•	 	 The BOD will be revised at the completion of the construction phase to reflect as-built conditions 

 

	2)	Preliminary Design Phase 

  
 B-2-7

	 	•	 	 Complete preliminary equipment layouts 

  

	 	•	 	 Complete Process Flow Diagrams depicting all major equipment, components and points of use 

 

	 	•	 	 Using the PFD(s) as a basis, develop detailed P&IDs for the entire systems (will include all points of use in the R&D facility)

  

	 	•	 	 P&IDs will include all valve ID numbers 

  

	 	•	 	 Points of use ordering on the P&ID will reflect physical plant layout, pipe branching and sequence of outlets on the detailed orthogonal plans

  

	 	•	 	 Develop a written Process Description which details operational procedures and process parameters and equipment sizing calculations. The Process
Description will be written in a manner such that it can be used for the subsequent preparation of Functional Specifications 

  

	3)	Detailed Design/ Construction Package Phase 

  

	 	•	 	 Preparation of the detailed orthogonal piping layout plans coordinated with the architectural and MEP (non process) plans.

  

	 	•	 	 Development of plans to included cost/benefit study of the installation U-bend transfer panels and/or valve requirements to assure product and process
integrity for the connection of process utilities. 

  

	 	•	 	 Prepare detailed specifications for each system. Detailed specifications to include, User Requirement Specifications, mechanical design, including
materials of construction, operating criteria, alarming criteria and requirements for integration into the BMS system. Integration of the PLCs into the BMS is currently under consideration. 

 

	 	•	 	 Preparation of the detailed specification to included system cost estimates and cost estimating support for system options

  

	 	•	 	 The development of the system specifications may require cost studies on redundancy options, energy management optimization, controls and
instrumentation philosophy 

  

	 	•	 	 Prepare an instrument index indicating, at a minimum, the following information: instrument tag number, P&ID drawing number, location, service
description, set points and once selected the manufacture, model number and calibrated range. 

  

	 	•	 	 Provide a detailed equipment list indicating, at a minimum, the following information: equipment tag number, P&ID drawing number, location, service
description, capacity (tank volumes, pump HP, Heat Ex thermal duty etc.), and once selected, the manufacture and model number. 

  

	 	•	 	 Prepare pre-purchase bid packages for long lead items, PW, WFI, Clean Steam are anticipated. Package to include the User Requirement specifications,
P&IDs, equipment schedules and system configuration layout. 

  

	4)	Construction Phase 

  

	 	•	 	 Review FAT and SAT documents for each system for completeness and accuracy. FAT and SAT documents are expected for: 

 

					
	 System
	  	 FAT
	  	 SAT

	 Purified Water
	  	Yes	  	Yes
	 WFI
	  	Yes	  	Yes
	 Clean Steam
	  	Yes	  	Yes
	 CDA
	  	No	  	Yes
	 Nitrogen
	  	No	  	Yes
	 Carbon Dioxide
	  	No	  	Yes
	 Vacuum
	  	No	  	Yes
	 Process Heating and Cooling Water
	  	No	  	Yes
	 Process Data Acquisition
	  	Yes	  	Yes
	 CIP for the fermentation vessels
	  	No	  	Yes
	 Waste Neutralization
	  	No	  	No

  

	 	•	 	 Participate in the execution of the FAT (at the vendor’s site) and SAT for the following systems: 

 

	 	•	 	 Purified Water (generation system) 

  

	 	•	 	 WFI (generation system) 

  
 B-2-8

	 	•	 	 Clean Steam 

  

	 	•	 	 Prepare the commissioning documents – pre-functional checklists and functional checklists. Commissioning will be completed for all systems:

  

	 	•	 	 Purified Water 

  

	 	•	 	 WFI 

  

	 	•	 	 Clean Steam 

  

	 	•	 	 CDA 

  

	 	•	 	 Nitrogen 

  

	 	•	 	 Carbon Dioxide 

  

	 	•	 	 Vacuum 

  

	 	•	 	 Process Heating and Cooling Water 

  

	 	•	 	 Process Data Acquisition 

  

	 	•	 	 CIP for the fermentation vessels 

  

	 	•	 	 Waste Neutralization 

  

	 	•	 	 Review of the IQ, OQ documents pre-execution for accuracy and completeness. 

  
 B-2-9

 ATTACHMENT 3 TO EXHIBIT B 

STRUCTURAL ENGINEER’S SCOPE OF WORK 
 The following is the preliminary scope of the work for the structural engineering services that will be provided. A detailed scope of work will be developed during the design phases. 

 

	1)	Main Structural Systems 

  

	 	•	 	 Below grade foundations and footings. 

  

	 	•	 	 Concrete slab floors, including trenches, pits and depressions. 

 

	2)	Secondary Structural Systems 

  

	 	•	 	 Supplemental structural supports and pads for mechanical, plumbing, fire protection, and electrical equipment. 

 

	 	•	 	 Supplemental structural supports for mechanical, plumbing, fire protection, and electrical distribution ductwork, piping and conduit.

  

	 	•	 	 Supplemental structural support systems for non-structural building elements. 

 

	3)	Non Structural Building elements 

  

	 	•	 	 Housekeeping pads. 

  

	 	•	 	 Architectural walls & ceiling supports systems. 

 

	 	•	 	 Seismic bracing systems for laboratory, mechanical, plumbing, fire protection, and electrical equipment, distribution ductwork, piping and conduit.

  

	4)	Detailed scope of work 

  

	 	•	 	 Main structural systems 

  

	 	•	 	 An approximately 600 sq ft of exterior equipment yard for boilers and a generator 

 

	 	•	 	 Roof platforms for new roof mounted mechanical equipment 

 

	 	•	 	 Structural slab modifications for trenches, pits and depressions. 

 

	 	•	 	 Floor penetrations in existing second floor slab for duct penetrations and for maintenance of the commercial lyophilizer 

 

	 	•	 	 Secondary structural systems 

  

	 	•	 	 Support for (3) roof mounted air handlers. 

  

	 	•	 	 Support for (2) cold room condensing units. 

  

	 	•	 	 Supplemental roof equipment screening. 

  

	 	•	 	 Supports for major roof mounted ducts and piping. 

  

	 	•	 	 Typical roof sleepers/supports. 

  

	 	•	 	 Support for emergency generator an boiler 

  

	 	•	 	 Miscellaneous housekeeping and equipment support slabs. 

 

	 	•	 	 The following laboratory/process equipment will require seismic restraint design: 

 

	 	•	 	 Autoclaves (3 types). 

  

	 	•	 	 Equipment washers (2 types). 

  

	 	•	 	 Biosafety cabinets (3 types). 

  

	 	•	 	 Laminar flow units (5 locations). 

  

	 	•	 	 Freezers (Typical). 

  

	 	•	 	 Refrigerators (Typical). 

  

	 	•	 	 Incubator (Typical). 

  

	 	•	 	 The following equipment/systems will be structurally designed by others, but will require review as Engineer of Record for deferred approval.

  

	 	•	 	 Air handlers. 

  

	 	•	 	 Steam boiler (2 types). 

  

	 	•	 	 Chillers. 

  

	 	•	 	 Main switchgear. 

  

	 	•	 	 Emergency generator. 

  

	 	•	 	 Automatic transfer switch (2). 

  

	 	•	 	 CIP skid. 

  

	 	•	 	 WFI/Clean Steam skid and tank. 

  
 B-3-1

	 	•	 	 Purified water skid and tank. 

  

	 	•	 	 Compressed air skid. 

  

	 	•	 	 Vacuum skid. 

  

	 	•	 	 LN2 tank and vaporizer. 

  

	 	•	 	 Fermentor. 

  

	 	•	 	 Decon tank. 

  

	 	•	 	 Filling equipment. 

  

	 	•	 	 Lyophilizers. 

  

	 	•	 	 Capping equipment. 

  

	 	•	 	 Inspection equipment. 

  

	 	•	 	 Cold room. 

  

	 	•	 	 Laboratory casework and fumehoods. 

  

	 	•	 	 General casework. 

  

	 	•	 	 Warehouse shelving and racking. 

  

	 	•	 	 MEP equipment attachment to structural support systems. 

 

	 	•	 	 MEP support systems. 

  

	 	•	 	 Seismic Clarifications: 

  

	 	•	 	 The manufacturing areas will require “clean room” solutions for the seismic anchorage design and details. For instance, no unistrut or floor
attachments that create crevices will be allowed. 

  

	 	•	 	 Typical vendor provided seismic solutions may not work in the clean room environment and will need to be re-designed. 

 

	 	•	 	 Cut sheets for the equipment will be available throughout the duration of the project as equipment purchase orders are issued and submittals are
received. 

  

	 	•	 	 The equipment will be installed throughout the duration of the project. 

 

	 	•	 	 There will be multiple packages submitted to the City in order to accommodate the schedule and receipt of information. 

 

	 	•	 	 The packages to the City will need to include the seismic calculations, design details and a floor plan clearly showing equipment location and the
details associated/linked with that item. 

  

	 	•	 	 The calculations will need to be in and 8.5” x 11” format and the details need to be shown in a standard E drawing format.

  

	 	•	 	 Six sets of each submittal to the City will be required (Three stamped sets for the City, one for the architect, one for the general contractor and one
for the owner) 

  

	 	•	 	 Documents to be issued in PDF format also. 

  

	 	•	 	 The design criteria will be based on Zone 4 with and importance factor (I p) of 1.0. 

  
 B-3-2

 ATTACHMENT 4 TO EXHIBIT B 

CONCEPTUAL BUDGET 
  

											
	

	  	 Revance Therapeutics
 EXECUTIVE SUMMARY
	  	 

  

									
	PROJECT:	 	Revance Therapeutics	  		  	DATE:	  	03/11/08
	LOCATION:	 	Newark, CA	  		  		  	Revision 2
	CLIENT:	 	Revance Therapeutics	  		  		  	
		 		  		  		  	

  

									
	AREA SUMMARY:	  		  		  		  	
		  	Office 1st Floor:	  		  	SF	  	
		  	Office 2nd Floor:	  		  	SF	  	
		  	Manufacturing, both Floors:	  	40,000	  	SF	  	
		  	TOTAL BUILDING:	  	40,000	  	SF	  	
					
		  	Service Yard Enclosure:	  	600	  	SF	  	

  

															
	 	  	 	  	Conceptual ROM
Manufacturing	 	  	 	 
	 Total Construction Costs
	  	 	  	CP-2	 	  	$/SF	 	  	 	 
					
	 Bass Estimate
	  		  	$	19,029,006	  	  	 	475.73	  	  			
					
	 Accepted Value Engineering
	  		  	$	 —  	  	  	 	—  	  	  			
		  		  	  
	  
	 	  	  
	  
	 	  			
					
	 REVISED Base Estimate
	  		  	$	19,029,006	  	  	 	475.73	  	  			
					
	 Liability Insurance
	  	1.1%	  	$	209,319	  	  	 	5.23	  	  			
					
	 Contractor’s Fee
	  	2.75%	  	$	529,054	  	  	 	13.23	  	  			
					
	 Design Contingency
	  	10.0%	  	$	1,906,738	  	  	 	47.67	  	  	 	**No contingency on Div 17	  
					
	 Course of Construction Contingency
	  	5.0%	  	$	1,048,706	  	  	 	26.22	  	  			
					
	 Builder’s Risk Insurance
	  		  	 	Excluded	  	  	 	—  	  	  			
		  		  	  
	  
	 	  	  
	  
	 	  			
	 Subtotal Base Estimate
	  		  	$	22,722,823	  	  	 	568.07	  	  			
					
	 Building Permits Allowance
	  	**ROM based on Newark Fee Schedule	  	$	101,873	  	  	 	2.55	  	  			
					
		  		  				  	 	—  	  	  			
					
		  		  	$	 —  	  	  	 	—  	  	  			
					
		  		  	$	 —  	  	  	 	—  	  	  			
		  		  	  
	  
	 	  	  
	  
	 	  			
					
	 Current Projection
	  		  	$	22,824,696	  	  	 	570.62	  	  			
		  		  	  
	  
	 	  	  
	  
	 	  			

 See Attached List of Exclusions and Qualifications 

 

					
	XL CONSTRUCTION	 	Executive Summary	 	CONFIDENTIAL

  
 B-4-1

					
	

	  	Revance Therapeutics	  	
	  	Exclusions and Qualifications	  	
	  	REVISION 2	  	

 The basis for the March II, 200S Budget is as follows: 
 Documentation: 
  

	 	•	 	 Drawings Dated: 2/22/08 - Test Fit Drawings by DGA. 

  

	 	•	 	 Specifications: None. 

Clarifications: 

The following clarifications are intended to qualify and identify specific items included or not included in the March 11, 2008
Budget. 
 The following items are not included: 

 

	 	  1	Any Sitework, including slurry seal of existing parking lot. 

  

	 	  2	Plan Check Fees, 

  

	 	  3	Encroachment Fees. 

  

	 	  4	Developer Fees. 

  

	 	  5	Builders Risk Insurance. Will be quoted for this site at a later date. 

 

	 	  6	Hazardous MATERIAL survey and abatement (if required). 

  

	 	  7	Tele/Data Cabling in MFG Area. (Rough in only included) Included Tele/Data for the Office Areas. 

 

	 	  8	Telephone utility costs. 

  

	 	  9	CCTV/Music and Paging Systems (Rough in only include) 

  

	 	10	Utility connection charges and fees (Gas, Electric, Sewer, etc.). 

  

	 	11	Off site work including and sidewalk upgrades. 

  

	 	12	Acceleration/off hours working. 

  

	 	13	Design and Engineering Fees. 

  

	 	14	Special Testing and Inspection. 

  

	 	15	Earthquake Insurance. 

  

	 	16	Start-up, commissioning, training, warranty, etc. of Owner’s equipment. 

 

	 	17	Signage, except for code required signage. 

  

	 	18	Escalation 

  

	 	19	Room furniture, fixtures and equipment. 

  

	 	20	Public space furniture, fixtures and equipment. 

  

	 	21	Elevator Upgrades. 

Qualifications/Allowances: 
  

	 	  1	Include cost for fumehoods, pallet racks, and cold rooms. Did not include other lab equipment. 

 

	 	  2	See detailed estimate for other inclusions and exclusions. 

 - End of Exclusions, Qualifications and Allowances- 

					
	

	  	Revance Therapeutics	  	
	  	CSI Systems Summary, ROM Conceptual Estimate	  	

  

							
	PROJECT:	 	Revance Therapeutics	  	UPDATED:	  	03/11/08
	LOCATION:	 	Newark, CA	  		  	Revision 2
	CLIENT:	 	Revance Therapeutics	  		  	

  

									
	AREA SUMMARY:	  		  		  		  	
		  	Office 1st Floor:	  		  	SF	  	
		  	Office 2nd Floor:	  		  	SF	  	
		  	Manufacturing, both Floors:	  	40,000	  	SF	  	
		  	TOTAL BUILDING:	  	40,000	  	SF	  	
					
		  	Service Yard Enclosure:	  	600	  	SF	  	
		  		  		  		  	

  

																			
	 CSI

DIVISION
	  	 DESCRIPTION
	  	 	 	 	Conceptual ROM Estimate
MANUFACTURING
TOTAL $/sf	 	  	 	 
	2	  	DEMOLITION	  				 	$	85,000	  	    	 	2.13	  	  			
	2	  	SITEWORK	  				 	$	54,900	  	    	 	1.37	  	  			
	3	  	CONCRETE	  				 	$	51,000	  	    	 	1.28	  	  			
	4	  	MASONRY	  				 	$	—  	  	    	 	—  	  	  			
	5	  	STEEL	  				 	$	138,500	  	    	 	3.46	  	  			
	6	  	WOOD AND PLASTICS	  				 	$	173,840	  	    	 	4.35	  	  			
	7	  	THERMAL & MOISTURE	  				 	$	120,125	  	    	 	3.00	  	  			
	8	  	DOORS/WINDOWS	  				 	$	527,350	  	    	 	13.18	  	  			
	9	  	FINISHES	  				 	$	1,458,089	  	    	 	36.45	  	  			
	10	  	SPECIALTIES	  				 	$	171,842	  	    	 	4.30	  	  			
	11	  	EQUIPMENT	  				 	$	405,000	  	    	 	10.13	  	  			
	12	  	FURNISHINGS	  				 	$	3,000	  	    	 	0.08	  	  			
	13	  	SPECIAL CONSTRUCTION	  				 	$	62,080	  	    	 	1.55	  	  			
	14	  	CONVEYING	  				 	$	—  	  	    	 	—  	  	  			
	15.1	  	FIRE PROTECTION	  				 	$	120,000	  	    	 	3.00	  	  			
	15.2	  	PLUMBING / PROCESS	  				 	$	4,200,000	  	    	 	105.00	  	  			
	15.3	  	HVAC, BALANCE & CONTROLS	  				 	$	8,059,600	  	    	 	201.49	  	  			
	16	  	ELECTRICAL, TELE/DATA & FA	  				 	$	1,495,488	  	    	 	37.39	  	  			
	17	  	BLDG MGT & SECURITY	  				 	$	700,000	  	    	 	17.50	  	  			
	25	  	GENERAL REQUIREMENTS	  				 	$	1,203,192	  	    	 	30.08	  	  			
		  		  				 	  
	  
	 	    	  
	  
	 	  			
		  		  	 	Subtotal	  	 	$	19,029,006	  	    	 	475.73	  	  			
					
	 Liability Insurance
	  	 	1.10	% 	 	$	209,319	  	    	 	5.23	  	  			
	 Contractors Fee
	  	 	2.75	% 	 	$	529,054	  	    	 	13.23	  	  			
	 Design Contingency
	  	 	10.00	% 	 	$	1,906,738	  	    	 	47.67	  	  	 	**No contingency on Div 17	  
	 Course of Construction Contingency
	  	 	5.00	% 	 	$	1,048,706	  	    	 	26.22	  	  			
	 Builder’s Risk Insurance
	  				 	 	Excluded	  	    	 	—  	  	  			
		  		  				 	  
	  
	 	    	  
	  
	 	  			
	 Total Estimated Cost to Date
	   
	 	$	22,722,823	  	    	 	568.07	  	  			
		  		  				 	  
	  
	 	    	  
	  
	 	  			

  

					
	XL CONSTRUCTION	 	CSI Summary	 	CONFIDENTIAL

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 1
 Revision 2
 3/11/2008

 
  

																			
	 Location
	  	CSI	 	  	Phase	  	 Description
	  	Quantity	  	Total Cost/Unit	  	Total
Amount	 	  	Notes / Comments
	Manufacturing	  				  		  		  		  		  				  	
		  	 	2010	  	  		  	DEMOLITION	  		  		  	 	85,000	  	  	
		  	 	2200	  	  		  	SITEWORK	  		  		  	 	54,900	  	  	
		  	 	3000	  	  		  	CONCRETE	  		  		  	 	51,000	  	  	
		  	 	4000	  	  		  	MASONRY	  		  		  				  	
		  	 	5000	  	  		  	STEEL	  		  		  	 	138,500	  	  	
		  	 	6000	  	  		  	WOOD and PLASTICS	  		  		  	 	173,840	  	  	
		  	 	7000	  	  		  	THERMAL & MOISTURE	  		  		  	 	120,125	  	  	
		  				  		  	PROTECTION	  		  		  				  	
		  	 	8000	  	  		  	DOORS & WINDOWS	  		  		  	 	527,350	  	  	
		  	 	9000	  	  		  	FINISHES	  		  		  	 	1,458,089	  	  	
		  	 	10000	  	  		  	SPECIALTIES	  		  		  	 	171,842	  	  	
		  	 	11000	  	  		  	EQUIPMENT	  		  		  	 	405,000	  	  	
		  	 	12000	  	  		  	FURNISHINGS	  		  		  	 	3,000	  	  	
		  	 	13000	  	  		  	SPECIAL CONSTRUCTION	  		  		  	 	62,080	  	  	
		  	 	14000	  	  		  	CONVEYING SYSTEMS	  		  		  				  	
		  	 	15000	  	  		  	MECHANICAL SYSTEMS	  		  		  	 	12,379,600	  	  	
		  	 	16000	  	  		  	ELECTRICAL	  		  		  	 	1,495,488	  	  	
		  	 	17001	  	  		  	BLDG SECURITY	  		  		  	 	700,000	  	  	
		  	 	25000	  	  		  	GENERAL CONDITIONS	  		  		  	 	1,203,192	  	  	
		  				  		  		  		  		  	  
	  
	 	  	
		  				  		  	Manufacturing	  		  		  	 	19,029,006	  	  	

 Partial Totals 
  

																															
	 Material
	  	 	5,000	  	  				  		  				 		  	 	0.056 /sf	  	  		  	 	0.03	% 	 			
	 Subcontract
	  	 	17,584,193	  	  				  		  				 		  	 	195.380 /sf	  	  		  	 	88.96	% 	 			
	 Equipment
	  	 	73,000	  	  				  		  				 		  	 	0.811 /sf	  	  		  	 	0.37	% 	 			
	 Other
	  				  				  		  				 		  				  		  				 			
		  	  
	  
	 	  				  		  				 		  	  
	  
	 	  		  	  
	  
	 	 			
		  	 	19,029,006	  	  	 	19,029,006	  	  		  				 		  	 	211.433 /sf	  	  		  	 	96.26	  	 	 	96.26	% 
										
	 Liability Insurance
	  	 	209,319	  	  				  		  	 	1.100	% 	 	T	  	 	2.326 /sf	  	  		  	 	1.06	% 	 			
	 Fee
	  	 	529,054	  	  				  		  	 	2.750	% 	 	T	  	 	5.878 /sf	  	  		  	 	2.68	% 	 			

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 2
 Revision 2
 3/11/2008

 
  
 Partial Totals 
  

																							
	 Builders Risk Insurance
	  		  				  		  		  	T	  				  		  		  	
	 Contingencies - See Exec Smry
	  		  				  		  		  	T	  				  		  		  	
	 Partial Total
	  		  	 	19,767,379	  	  		  		  		  	 	219.638 /sf	  	  		  		  	

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 1
 Revision 2
 3/11/2008

 
  

																													
	 Location
	 	Group	 	 	Phase	 	 	Location	 	 Description
	 	Quantity	 	 	Total Cost/Unit	 	 	Total
Amount	 	 	 Notes / Comments
	 	CSI
	Manufacturing	 				 				 		 		 				 				 				 		 	
		 	 	2005.00	  	 				 		 	 ABATEMENT
	 				 				 				 		 	
		 				 	 	2010.00	  	 		 	 Abatement
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Haz. Mat. Abatement - By Owner
	 	 	ls	  	 	 	/ls	  	 				 	NIC - See Notes and Exclusions	 	
										
		 	 	2060.00	  	 				 		 	 SELECTIVE BLOG DEMO
	 				 				 				 		 	
		 				 	 	2061.00	  	 		 	 Selective Building Demo
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Selective BLDG Demo
	 	 	40,000.00 sf	  	 	 	1.50 /sf	  	 	 	60,000	  	 		 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Selective Building Demo
	 				 	 	/sf	  	 	 	60,000	  	 		 	
										
		 				 	 	2062.00	  	 		 	 Demo: Int. Concrete
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Demo Interior Concrete
	 	 	40,000.00 sf	  	 	 	0.63 /sf	  	 	 	25,000	  	 	For Pits, Trenches, Footings	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Demo: Int. Concrete
	 				 	 	/sf	  	 	 	25,000	  	 		 	
		 				 				 		 	 SELECTIVE BLDG DEMO
	 				 	 	/sf	  	 	 	85,000	  	 		 	
										
		 	 	2116.00	  	 				 		 	 DEWATERING
	 				 				 				 		 	
		 				 	 	2117.00	  	 		 	 Dewatering
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Dewatering Allowance
	 	 	1.00 ls	  	 	 	/ls	  	 				 	Excluded, S/B Above Groundwater	 	
										
		 	 	2200.00	  	 				 		 	 EARTHWORK
	 				 				 				 		 	
		 				 	 	2215.00	  	 		 	 Earthwork: Site Grading
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Excavation & Offhaul for Pits, Footings & Underslab Trenches
	 	 	400.00 cy	  	 	 	37.50 /cy	  	 	 	15,000	  	 		 	
		 				 				 	Manufacturing	 	 Service Yard (More than Generator Yard)
	 	 	600.00 sf	  	 	 	5.83 /sf	  	 	 	3,500	  	 		 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Earthwork: Site Grading
	 				 	 	/sf	  	 	 	18,500	  	 		 	
										
		 				 	 	2240.00	  	 		 	 Erosion/Sediment Control
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 SWPPP/Erosion Control
	 	 	1.00 ls	  	 	 	/ls	  	 				 	Excluded, Not Required	 	
		 				 				 		 	 EARTHWORK
	 				 	 	/sf	  	 	 	18,500	  	 		 	
										
		 	 	2300.00	  	 				 		 	 SITE CONCRETE
	 				 				 				 		 	
		 				 	 	2305.00	  	 		 	 Site Concrete
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Site Concrete Modifications
	 	 	1.00 ls	  	 	 	/ls	  	 				 	Excluded	 	
										
		 	 	2500.00	  	 				 		 	 ASPHALT PAVING
	 				 				 				 		 	
		 				 	 	2505.00	  	 		 	 Asphalt Paving
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Asphalt Paving / Striping Modifications
	 	 	600.00 sf	  	 	 	/sf	  	 				 	Excluded, Not Required	 	
										
		 	 	2800.00	  	 				 		 	 UTILITIES
	 				 				 				 		 	
		 				 	 	2801.00	  	 		 	 Underground Utilities
	 				 				 				 		 	

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 2
 Revision 2
 3/11/2008

 
  

																													
	 Location
	 	Group	 	 	Phase	 	 	Location	 	 Description
	 	Quantity	 	 	Total Cost/Unit	 	 	Total
Amount	 	 	 Notes / Comments
	 	CSI
		 				 	 	2801.00	  	 		 	 Underground Utilities
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Utility Modification due to Service Yard
	 	 	lf	  	 	 	/lf	  	 				 	Excluded	 	
										
		 				 	 	2804.00	  	 		 	 Domestic Water Lines
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 2” Pipe, PVC
	 	 	0.00 lf	  	 	 	/lf	  	 				 	 Existing Service to
 Building
	 	
										
		 				 	 	2806.00	  	 		 	 Gas Lines
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Gas Line Upgrade from Low to Medium Pressure
	 	 	0.00 lf	  	 	 	/lf	  	 				 	No Change in Piping	 	
		 				 				 	Manufacturing	 	 (N) Gas Meter
	 	 	1.00 ea	  	 	 	/ea	  	 				 	Excluded, by PG&E	 	
										
		 				 	 	2808.00	  	 		 	 Sanitary Sewer
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 6” Sanitary Sewer / Lab Waste
	 	 	175.00 lf	  	 	 	42.00 /lf	  	 	 	7,350	  	 		 	
		 				 				 	Manufacturing	 	 Clean Outs
	 	 	2.00 ea	  	 	 	400.00/ea	  	 	 	800	  	 		 	
		 				 				 	Manufacturing	 	 Tie In To Existing
	 	 	1.00 ea	  	 	 	750.00 /ea	  	 	 	750	  	 		 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Sanitary Sewer
	 				 	 	/sf	  	 	 	8,900	  	 		 	
		 				 				 		 	 UTILITIES
	 				 	 	/sf	  	 	 	8,900	  	 		 	
										
		 	 	2850.00	  	 				 		 	 SITE ELECTRICAL
	 				 				 				 		 	
		 				 	 	2852.00	  	 		 	 Site Electrical
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Site Electrical
	 	 	0.00 ls	  	 	 	0.00 /ls	  	 	 	0	  	 	Excluded	 	
										
		 	 	2900.00	  	 				 		 	 LANDSCAPE & IRRIGATE
	 				 				 				 		 	
		 				 	 	2905.00	  	 		 	 Landscaping & Irrigation
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Landscape Modifications
	 	 	1.00 ls	  	 	 	15,000.00/ls	  	 	 	15,000	  	 	Allowance for Construction Access	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Landscaping & Irrigation
	 				 	 	/sf	  	 	 	15,000	  	 		 	
		 				 				 		 	 LANDSCAPE & IRRIGATE
	 				 	 	/sf	  	 	 	15,000	  	 		 	
										
		 	 	2995.00	  	 				 		 	 MISC. SITE
	 				 				 				 		 	
		 				 	 	2996.00	  	 		 	 Misc Site Item
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Temp Lunch Area
	 	 	1.00 ls	  	 	 	10,000.00 /ls	  	 	 	10,000	  	 		 	
		 				 				 	Manufacturing	 	 Street Sweeping
	 	 	0.00 ls	  	 	 	0.00 /ls	  	 	 	0	  	 	Not Required, By Landlord	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Misc Site Item
	 				 	 	/sf	  	 	 	10,000	  	 		 	
		 				 				 		 	 MISC. SITE
	 				 	 	/sf	  	 	 	10,000	  	 		 	
										
		 	 	2999.00	  	 				 		 	 SUPPORT & CONTROL
	 				 				 				 		 	
		 				 	 	2999.20	  	 		 	 Underground Locating
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 UG Locating Service
	 	 	1,00 ls	  	 	 	2,500.00 /ls	  	 	 	2.500	  	 		 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Underground Locating
	 				 	 	/sf	  	 	 	2,500	  	 		 	
		 				 				 		 	 SUPPORT & CONTROL
	 				 	 	/sf	  	 	 	2,500	  	 		 	

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 3
 Revision 2
 3/11/2008

 
  

																													
	 Location
	 	Group	 	 	Phase	 	 	Location	 	 Description
	 	Quantity	 	 	Total Cost/Unit	 	 	Total
Amount	 	 	 Notes / Comments
	 	CSI
										
		 	 	3000.00	  	 				 		 	 CONCRETE
	 				 				 				 		 	
		 				 	 	3103.00	  	 		 	 Concrete Assemblies
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Trench Patch & Dowels
	 	 	1,000.00 sf	  	 	 	17.50 /sf	  	 	 	17,500	  	 		 	
		 				 				 	Manufacturing	 	 Mechanical Pads / Curbs
	 	 	1.00 ls	  	 	 	20,000.00/ls	  	 	 	20,000	  	 	Allowance	 	
		 				 				 	Manufacturing	 	 Concrete Assemblies @ Comm’l Lyo
	 	 	30.00 cy	  	 	 	/cy	  	 				 	Excluded	 	
		 				 				 	Manufacturing	 	 Service Yard Concrete Slab / Footings
	 	 	600.00 sf	  	 	 	16.67 /sf	  	 	 	10,000	  	 		 	
		 				 				 	Manufacturing	 	 Misc. Grouting/Patch
	 	 	1.00 ls	  	 	 	3,500.00 /ls	  	 	 	3,500	  	 	Allowance	 	
		 				 				 	Manufacturing	 	 Autoclave Pits / Hoists Pit
	 	 	0.00 ea	  	 	 	0.00 /ea	  	 	 	0	  	 	Excluded	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Concrete Assemblies
	 				 	 	/sf	  	 	 	51,000	  	 		 	
		 				 				 		 	 CONCRETE
	 				 	 	/sf	  	 	 	51,000	  	 		 	
										
		 	 	4000.00	  	 				 		 	 MASONRY
	 				 				 				 		 	
		 				 	 	4005.00	  	 		 	 CMU Walls
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 CMU Wall, 10’ High
	 	 	0.00 sf	  	 	 	0.00 /sf	  	 	 	0	  	 	Excluded, Not Required	 	
										
		 	 	5100.00	  	 				 		 	 STEEL
	 				 				 				 		 	
		 				 	 	5105.00	  	 		 	 Structural Steel
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Structural Steel Upgrades
	 	 	ls	  	 	 	/ls	  	 				 	Excluded, Not Required	 	
		 				 				 	Manufacturing	 	 Canopy at Service Yard
	 	 	ls	  	 	 	/ls	  	 				 	Excluded, Not Required	 	
										
		 	 	5300.00	  	 				 		 	 METAL DECK
	 				 				 				 		 	
		 				 	 	5305.00	  	 		 	 Steel Deck
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Metal Deck
	 	 	0.00 sf	  	 	 	0.00 /sf	  	 	 	0	  	 	Excluded, Not Required	 	
										
		 	 	5500.00	  	 				 		 	 MISCELLANEOUS STEEL
	 				 				 				 		 	
		 				 	 	5503.00	  	 		 	 Subcontract Misc Steel
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Misc Steel for Support / Platform
	 	 	40,000.00 sf	  	 	 	1.25 /sf	  	 	 	50,000	  	 		 	
		 				 				 	Manufacturing	 	 Roof Screen Substructure & Support
	 	 	200.00 /lf	  	 	 	400.00 /lf	  	 	 	80,000	  	 		 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Subcontract Misc Steel
	 				 	 	/sf	  	 	 	130,000	  	 		 	
										
		 				 	 	5549.00	  	 		 	 Bollards
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Bollards
	 	 	10.00 ea	  	 	 	850.00 /ea	  	 	 	8,500	  	 	At Quarantine Release	 	
		 				 				 	Manufacturing	 	 Pallet Jack Guardrails
	 	 	ea	  	 	 	/ea	  	 				 	Excluded; Use Fencing	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Bollards
	 				 	 	/sf	  	 	 	8,500	  	 		 	
		 				 				 		 	 MISCELLANEOUS STEEL
	 				 	 	/sf	  	 	 	138,500	  	 		 	
										
		 	 	5800.00	  	 				 		 	 EXPANSION JOINT COVERS
	 				 				 				 		 	

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 4
 Revision 2
 3/11/2008

 
  
  

																													
	 Location
	 	Group	 	 	Phase	 	 	Location	 	 Description
	 	Quantity	 	 	Total Cost/Unit	 	 	Total
Amount	 	 	 Notes / Comments
	 	CSI
		 				 	 	5810.00	  	 		 	 Expansion Joint
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Expansion Joints
	 	 	0.00 lf 	  	 	 	0.00 /lf 	  	 	 	0	  	 	Excluded, Not Required	 	
										
		 	 	6160.00	  	 				 		 	 SEISMIC CARPENTRY
	 				 				 				 		 	
		 				 	 	6165.00	  	 		 	 Seismic Bracing
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Seismic / Roof Infills
	 	 	ea 	  	 	 	/ea 	  	 				 		 	
										
		 	 	6170.00	  	 				 		 	 BLOCKING & MISC FRAMING
	 				 				 				 		 	
		 				 	 	6190.00	  	 		 	 Misc Wood Block/Frame Int
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Rough Carpentry/Wood Blocking
	 	 	40,000.00 sf 	  	 	 	0.54 /sf 	  	 	 	21,560	  	 		 	
		 				 				 	Manufacturing	 	 Walkable Ceiling Framing
	 	 	0.00 sf 	  	 	 	0.00 /sf 	  	 	 	0	  	 	Excluded, Not Required	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Misc Wood Block/Frame Int
	 				 	 	/sf 	  	 	 	21,560	  	 		 	
		 				 				 		 	 BLOCKING & MISC FRAMING
	 				 	 	/sf 	  	 	 	21,560	  	 		 	
										
		 	 	6200.00	  	 				 		 	 CASEWORK & MILLWORK
	 				 				 				 		 	
		 				 	 	6201.00	  	 		 	 Finish Carpentry
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Casework / Millwork
	 	 	lf 	  	 	 	/lf 	  	 				 	Excluded, None Shown	 	
										
		 	 	6999.00	  	 				 		 	 SUPPORT & CONTROL
	 				 				 				 		 	
		 				 	 	6999.20	  	 		 	 Engineering/Layout
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Layout Verifications
	 	 	40,000.00 sf 	  	 	 	0.41 /sf 	  	 	 	16,280	  	 		 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Engineering/Layout
	 				 	 	/sf 	  	 	 	16,280	  	 		 	
										
		 				 	 	6999.45	  	 		 	 Small Tools & Equipment
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Material Handling & Hoisting
	 	 	8.00 mo 	  	 	 	6,000.00 /mo 	  	 	 	48,000	  	 	Gradall / Hyster Lift	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Small Tools & Equipment
	 				 	 	/sf 	  	 	 	48,000	  	 		 	
										
		 				 	 	6999.50	  	 		 	 Safety
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Safety / Protection
	 	 	40,000.00 sf 	  	 	 	1.58 /sf 	  	 	 	63,000	  	 	25K Safety Mat’ls, 500 Hours Safety Labor	 	
		 				 				 	Manufacturing	 	 Barricades / Phasing
	 	 	1.00 ls 	  	 	 	25,000.00 /ls 	  	 	 	25,000	  	 		 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Safety
	 				 	 	/sf 	  	 	 	88,000	  	 		 	
		 				 				 		 	 SUPPORT & CONTROL
	 				 	 	/sf 	  	 	 	152,280	  	 		 	
										
		 	 	7200.00	  	 				 		 	 INSULATION
	 				 				 				 		 	
		 				 	 	7205.00	  	 		 	 Building Insulation
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Insulation Wall Only
	 	 	33,500.00 sf 	  	 	 	0.75 /sf 	  	 	 	25,125	  	 	Excluded at Ceiling	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Building Insulation
	 				 	 	/sf 	  	 	 	25,125	  	 		 	
		 				 				 		 	 INSULATION
	 				 	 	/sf 	  	 	 	25,125	  	 		 	
										
		 	 	7250.00	  	 				 		 	 FIREPROOF & FIRESTOP
	 				 				 				 		 	
		 				 	 	7255.00	  	 		 	 Fireproofing: Spray On
	 				 				 				 		 	

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 5
 Revision 2
 3/11/2008

 
  
  

																													
	 Location
	 	Group	 	 	Phase	 	 	Location	 	 Description
	 	Quantity	 	 	Total Cost/Unit	 	 	Total
Amount	 	 	 Notes / Comments
	 	CSI
		 				 	 	7255.00	  	 		 	 Fireproofing: Spray On
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Fireproof Select Area
	 	 	2,500.00 sf 	  	 	 	6.00 /sf 	  	 	 	15,000	  	 	Excluded Not Required	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Fireproofing: Spray On
	 				 	 	/sf 	  	 	 	15,000	  	 		 	
										
		 				 	 	7260.00	  	 		 	 Firestopping
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Firestop Patch
	 	 	40,000.00 sf 	  	 	 	/sf 	  	 				 	NIC, (E) at Bldg Perimeter, Top of Wall with Drywall	 	
		 				 				 		 	 FIREPROOF & FIRESTOP
	 				 	 	/sf 	  	 	 	15,000	  	 		 	
										
		 	 	7500.00	  	 				 		 	 ROOFING
	 				 				 				 		 	
		 				 	 	7505.00	  	 		 	 Built Up Roofing
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Roof Patch
	 	 	20,000.00 sf 	  	 	 	1.25 /sf 	  	 	 	25,000	  	 	Patch for New Mechanical Equipment & Roof Screen	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Built Up Roofing
	 				 	 	/sf 	  	 	 	25,000	  	 		 	
		 				 				 		 	 ROOFING
	 				 	 	/sf 	  	 	 	25,000	  	 		 	
										
		 	 	7600.00	  	 				 		 	 FLASHING & SHEET METAL
	 				 				 				 		 	
		 				 	 	7605.00	  	 		 	 Architectural Sheet Metal
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Flashing / Sheet Metal
	 	 	40,000.00 sf 	  	 	 	0.50 /sf 	  	 	 	20,000	  	 	At Roof Screen, New Penetrations, AHU Curbs	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Architectural Sheet Metal
	 				 	 	/sf 	  	 	 	20,000	  	 		 	
		 				 				 		 	 FLASHING & SHEET METAL
	 				 	 	/sf 	  	 	 	20,000	  	 		 	
										
		 	 	7900.00	  	 				 		 	 CAULKING & SEALANTS
	 				 				 				 		 	
		 				 	 	7912.00	  	 		 	 Caulking – GC
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Misc Caulking & Sealants
	 	 	40,000.00 sf 	  	 	 	0.63 /sf 	  	 	 	25,000	  	 	(N) Buildout Only	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Caulking – GC
	 				 	 	/sf 	  	 	 	25,000	  	 		 	
		 				 				 		 	 CAULKING & SEALANTS
	 				 	 	/sf 	  	 	 	25,000	  	 		 	
										
		 	 	7999.00	  	 				 		 	 SUPPORT & CONTROL
	 				 				 				 		 	
		 				 	 	7999.50	  	 		 	 Protection
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Roof Protection / Material Staging
	 	 	1.00 ls 	  	 	 	10,000.00 /ls 	  	 	 	10,000	  	 		 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Protection
	 				 	 	/sf 	  	 	 	10,000	  	 		 	
		 				 				 		 	 SUPPORT & CONTROL
	 				 	 	/sf 	  	 	 	10,000	  	 		 	
										
		 	 	8000.00	  	 				 		 	 DOORS & HARDWARE
	 				 				 				 		 	
		 				 	 	8010.00	  	 		 	 Doors Frames Hardware
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Single Doors
	 	 	62.00 ea 	  	 	 	1,850.00 /ea 	  	 	 	114,700	  	 		 	
		 				 				 	Manufacturing	 	 Uneven Pairs
	 	 	25.00 ea 	  	 	 	3,200.00 /ea 	  	 	 	80,000	  	 		 	
		 				 				 	Manufacturing	 	 Pairs
	 	 	7.00 ea 	  	 	 	3,500.00 /ea 	  	 	 	24,500	  	 		 	
		 				 				 	Manufacturing	 	 Extra Clean Area Door Upgrade
	 	 	10.00 lvs 	  	 	 	450.00 /lvs 	  	 	 	4,500	  	 	Armour Plates, Door Top/Bottoms, Flush Frames	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Doors Frames Hardware
	 				 	 	/sf 	  	 	 	223,700	  	 		 	
										
		 				 	 	8050.00	  	 		 	 Coiling Doors & Grilles
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Overhead Coiling Door
	 	 	ea 	  	 	 	/ea 	  	 				 	Excluded	 	

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 6
 Revision 2
 3/11/2008

 
  
  

																													
	 Location
	 	Group	 	 	Phase	 	 	Location	 	 Description
	 	Quantity	 	 	Total Cost/Unit	 	 	Total
Amount	 	 	 Notes / Comments
	 	CSI
										
		 				 	 	8062.00	  	 		 	 Clean Room Doors
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Pass Thru, Small
	 	 	6.00 ea 	  	 	 	5,000.00 /ea 	  	 	 	30,000	  	 		 	
		 				 				 	Manufacturing	 	 Pass Thru, Large
	 	 	3.00 ea 	  	 	 	8,000.00 /ea 	  	 	 	24,000	  	 		 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Clean Room Doors
	 				 	 	/sf 	  	 	 	54,000	  	 		 	
		 				 				 		 	 DOORS & HARDWARE
	 				 	 	/sf 	  	 	 	277,700	  	 		 	
										
		 	 	8400.00	  	 				 		 	 GLASS, GLAZING, WINDOWS
	 				 				 				 		 	
		 				 	 	8420.00	  	 		 	 Int. Glass & Glass System
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Window Film @ Exterior Glazing
	 	 	0.00 sf 	  	 	 	0.00 /sf 	  	 	 	0	  	 	Excluded, Not Required	 	
		 				 				 	Manufacturing	 	 Allowance for Interior Glazing
	 	 	40,000.00 sf 	  	 	 	1.52 /sf 	  	 	 	60,800	  	 	 Assume View Windows in

Manufacturing Area and New Offices/Conf Sidelights
	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Int. Glass & Glass System
	 				 	 	/sf 	  	 	 	60,800	  	 		 	
		 				 				 		 	 GLASS, GLAZING, WINDOWS
	 				 	 	/sf 	  	 	 	60,800	  	 		 	
										
		 	 	8800.00	  	 				 		 	 HARDWARE
	 				 				 				 		 	
		 				 	 	8810.00	  	 		 	 Hardware
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Interlock Hardware
	 	 	47.00 ea 	  	 	 	2,500.00 /ea 	  	 	 	117,500	  	 		 	
		 				 				 	Manufacturing	 	 Panic Hardware
	 	 	1.00 ls 	  	 	 	7,500.00 /ls 	  	 	 	7,500	  	 	Allowance	 	
		 				 				 	Manufacturing	 	 Maglocks At Exterior Doors
	 	 	5.00 pr 	  	 	 	3,000.00 /pr 	  	 	 	15,000	  	 		 	
		 				 				 	Manufacturing	 	 Hold Opens
	 	 	1.00 ls 	  	 	 	15,000.00 /ls 	  	 	 	15,000	  	 	Allowance	 	
		 				 				 	Manufacturing	 	 Card Readers Rough In
	 	 	50.00 ea 	  	 	 	550.00 /ea 	  	 	 	27,500	  	 	Allowance	 	
		 				 				 	Manufacturing	 	 Glass Break Rough In
	 	 	1.00 ea 	  	 	 	350.00 /ea 	  	 	 	350	  	 	Allowance	 	
		 				 				 	Manufacturing	 	 Key Pad / Motion Detector Rough In
	 	 	10.00 ea 	  	 	 	600.00 /ea 	  	 	 	6,000	  	 	Allowance	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Hardware
	 				 	 	/sf 	  	 	 	188,850	  	 		 	
		 				 				 		 	 HARDWARE
	 				 	 	/sf 	  	 	 	188,850	  	 		 	
										
		 	 	9101.00	  	 				 		 	 SCAFFOLDING / SHORING
	 				 				 				 		 	
		 				 	 	9102.00	  	 		 	 Scaffold / Shoring
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Scaffold / Shoring
	 	 	1.00 ls 	  	 	 	15,000.00 /ls 	  	 	 	15,000	  	 	Allowance	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Scaffold / Shoring
	 				 	 	/sf 	  	 	 	15,000	  	 		 	
		 				 				 		 	 SCAFFOLDING / SHORING
	 				 	 	/sf 	  	 	 	15,000	  	 		 	
										
		 	 	9200.00	  	 				 		 	 METAL STUD & DRYWALL
	 				 				 				 		 	
		 				 	 	9220.00	  	 		 	 GWB Systems
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Drywall Partitions – Thickened Wall
	 	 	11,700.00 sf 	  	 	 	10.00 /sf 	  	 	 	117,000	  	 		 	
		 				 				 	Manufacturing	 	 Drywall Partitions – Full Height
	 	 	22,450.00 sf 	  	 	 	10.25 /sf 	  	 	 	230,113	  	 		 	
		 				 				 	Manufacturing	 	 Drywall Ceiling
	 	 	12,249.00 sf 	  	 	 	8.00 /sf 	  	 	 	97,992	  	 		 	
		 				 				 	Manufacturing	 	 Wall Furring Patch
	 	 	11,600.00 sf 	  	 	 	0.86 /sf 	  	 	 	10,000	  	 		 	
		 				 				 	Manufacturing	 	 Column Furring
	 	 	10.00 ea 	  	 	 	/ea 	  	 				 		 	
		 				 				 	Manufacturing	 	 Drywall Soffits
	 	 	ls 	  	 	 	/ls 	  	 				 		 	
		 				 				 	Manufacturing	 	 Coved Corners
	 	 	40,000.00 sf 	  	 	 	1.00 /sf 	  	 	 	40,000	  	 	Allowance	 	
		 				 				 	Manufacturing	 	 Impact Resistant Drywall
	 	 	40,020.00 sf 	  	 	 	0.63 /sf 	  	 	 	25,000	  	 		 	

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 7
 Revision 2
 3/11/2008

 
  
  

																											
	 Location
	 	Group	 	Phase	 	 	Location	 	 Description
	 	Quantity	 	 	Total Cost/Unit	 	 	Total
Amount	 	 	 Notes / Comments
	 	CSI
		 		 	 	9220.00	  	 		 	 GWB Systems
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Access Doors
	 	 	40,000.00 sf 	  	 	 	0.38 /sf 	  	 	 	15,000	  	 		 	
		 		 				 	Manufacturing	 	 Drywall Assemblies Miscellaneous
	 	 	40,000.00 sf 	  	 	 	0.63 /sf 	  	 	 	25,000	  	 	Backing, Level 5, Misc	 	
		 		 				 	Manufacturing	 	 Drywall Shafts
	 	 	1.00 ls 	  	 	 	40,000.00 /ls 	  	 	 	40,000	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 GWB Systems
	 				 	 	/sf 	  	 	 	600,105	  	 		 	
		 		 				 		 	 METAL STUD & DRYWALL
	 				 	 	/sf 	  	 	 	600,105	  	 		 	
										
		 	9300.00	 				 		 	 TILE & TERRAZZO
	 				 				 				 		 	
		 		 	 	9305.00	  	 		 	 Tile: Floor & Wall
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Tile
	 	 	1,300.00 sf 	  	 	 	18.00 /sf 	  	 	 	23,400	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Tile: Floor & Wall
	 				 	 	/sf 	  	 	 	23,400	  	 		 	
		 		 				 		 	 TILE & TERRAZZO
	 				 	 	/sf 	  	 	 	23,400	  	 		 	
										
		 	9500.00	 				 		 	 CEILINGS
	 				 				 				 		 	
		 		 	 	9505.00	  	 		 	 Ceiling: Acoustical Tile
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Clean Lay in 2’ x 4’ Mylar Panel
	 	 	11,766.00 sf 	  	 	 	6.00 /sf 	  	 	 	70,596	  	 		 	
		 		 				 	Manufacturing	 	 Lay in 2’ x 4’ Cortega Panel
	 	 	4,476.00 sf 	  	 	 	5.15 /sf 	  	 	 	23,051	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Ceiling: Acoustical Tile
	 				 	 	/sf 	  	 	 	93,647	  	 		 	
		 		 				 		 	 CEILINGS
	 				 	 	/sf 	  	 	 	93,647	  	 		 	
										
		 	9600.00	 				 		 	 FLOORING
	 				 				 				 		 	
		 		 	 	9610.00	  	 		 	 Specialty Flooring
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Sealed Concrete
	 	 	8,729.00 sf 	  	 	 	/sf 	  	 				 	Excluded	 	
		 		 				 	Manufacturing	 	 Moisture Barrier at 1st Floor SV Areas
	 	 	3,500.00 sf 	  	 	 	5.40 /sf 	  	 	 	18,900	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Specialty Flooring
	 				 	 	/sf 	  	 	 	18,900	  	 		 	
										
		 		 	 	9620.00	  	 		 	 VCT Flooring
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 VCT Tile
	 	 	8,429.00 sf 	  	 	 	3.50 /sf 	  	 	 	29,502	  	 		 	
		 		 				 	Manufacturing	 	 Rubber Base
	 	 	3,152.00 lf 	  	 	 	2.00 /lf 	  	 	 	6,304	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 VCT Flooring
	 				 	 	/sf 	  	 	 	35,806	  	 		 	
										
		 		 	 	9622.00	  	 		 	 Sheet Vinyl Flooring
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Sheet Vinyl
	 	 	7,000.00 sf 	  	 	 	8.00 /sf 	  	 	 	56,000	  	 	Adjusted SF by Ratio for Spaces	 	
		 		 				 	Manufacturing	 	 Floor Prep
	 	 	7,000.00 sf 	  	 	 	0.75 /sf 	  	 	 	5,250	  	 		 	
		 		 				 	Manufacturing	 	 Sheet Vinyl Coved Base
	 	 	1,500.00 lf 	  	 	 	8.00 /lf 	  	 	 	12,000	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Sheet Vinyl Flooring
	 				 	 	/sf 	  	 	 	73,250	  	 		 	
										
		 		 	 	9635.00	  	 		 	 Epoxy Floor
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Epoxy Flooring
	 	 	9,715.00 sf 	  	 	 	12.00 /sf 	  	 	 	116,580	  	 		 	
		 		 				 	Manufacturing	 	 Epoxy Base
	 	 	3,649.00 lf 	  	 	 	12.00 /lf 	  	 	 	43,788	  	 		 	
		 		 				 	Manufacturing	 	 Moisture Tests
	 	 	20.00 ea 	  	 	 	50.00 /ea 	  	 	 	1,000	  	 		 	
		 		 				 	Manufacturing	 	 Bead Blast
	 	 	9,715.00 sf 	  	 	 	2.00 /sf 	  	 	 	19,430	  	 		 	
		 		 				 	Manufacturing	 	 Minor Patching
	 	 	9,715.00 sf 	  	 	 	1.00 /sf 	  	 	 	9,715	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Epoxy Floor
	 				 	 	/sf 	  	 	 	190,513	  	 		 	
										
		 		 	 	9640.00	  	 		 	 Flooring Carpet
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Carpet
	 	 	372.00 sf 	  	 	 	4.50 /sf 	  	 	 	1,674	  	 		 	

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 8
 Revision 2
 3/11/2008

 
  
  

																											
	 Location
	 	Group	 	Phase	 	 	Location	 	 Description
	 	Quantity	 	 	Total Cost/Unit	 	 	Total
Amount	 	 	 Notes / Comments
	 	CSI
		 		 	 	9640.00	  	 		 	 Flooring Carpet
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Moisture Tests
	 	 	2.00 ea 	  	 	 	50.00 /ea 	  	 	 	100	  	 		 	
		 		 				 	Manufacturing	 	 Floor Prep
	 	 	372.00 sf 	  	 	 	0.50 /sf 	  	 	 	186	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Flooring Carpet
	 				 	 	/sf 	  	 	 	1,960	  	 		 	
		 		 				 		 	 FLOORING
	 				 	 	/sf 	  	 	 	320,429	  	 		 	
										
		 	9900.00	 				 		 	 PAINTING & WALL COVERING
	 				 				 				 		 	
		 		 	 	9910.00	  	 		 	 Painting & Wall Covering
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Latex Wall Paint
	 	 	49,820.00 sf 	  	 	 	0.80 /sf 	  	 	 	39,856	  	 		 	
		 		 				 	Manufacturing	 	 Latex Ceiling Paint
	 	 	1.00 ls 	  	 	 	2,500.00 /ls 	  	 	 	2,500	  	 	530 sf in showers, etc.	 	
		 		 				 	Manufacturing	 	 3rd Coat after Finishes
	 	 	49,820.00 sf 	  	 	 	0.20 /sf 	  	 	 	9,964	  	 		 	
		 		 				 	Manufacturing	 	 Paint Doors & Frames
	 	 	101.00 ea 	  	 	 	350.00 /ea 	  	 	 	35,350	  	 		 	
		 		 				 	Manufacturing	 	 Paint Exposed Structure
	 	 	8,080.00 sf 	  	 	 	1.00 /sf 	  	 	 	8,080	  	 		 	
		 		 				 	Manufacturing	 	 Paint MEP Systems
	 	 	0.00 ls 	  	 	 	0.00 /ls 	  	 	 	0	  	 	Excluded, Not Required	 	
		 		 				 	Manufacturing	 	 Exterior Painting Allowance
	 	 	1.00 ls 	  	 	 	1,500.00 /ls 	  	 	 	1,500	  	 	Allowance at Generator Yard only	 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Painting & Wall Covering
	 				 	 	/sf 	  	 	 	97,250	  	 		 	
										
		 		 	 	9940.00	  	 		 	 Epoxy Coatings & Systems
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Saniflex Epoxy Walls
	 	 	10,000.00 sf 	  	 	 	6.00 /sf 	  	 	 	60,000	  	 	Adjusted SF by Ratio for Spaces	 	
		 		 				 	Manufacturing	 	 Epoxy Wall Paint
	 	 	26,490.00 sf 	  	 	 	1.50 /sf 	  	 	 	39,735	  	 	Adjusted SF by Ratio for Spaces	 	
		 		 				 	Manufacturing	 	 Saniflex Epoxy Ceilings
	 	 	2,500.00 sf 	  	 	 	6.00 /sf 	  	 	 	15,000	  	 	Adjusted SF by Ratio for Spaces	 	
		 		 				 	Manufacturing	 	 Epoxy Ceiling Paint
	 	 	7,215.00 sf 	  	 	 	1.50 /sf 	  	 	 	10,823	  	 	Adjusted SF by Ratio for Spaces	 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Epoxy Coatings & Systems
	 				 	 	/sf 	  	 	 	125,558	  	 		 	
		 		 				 		 	 PAINTING & WALL COVERING
	 				 	 	/sf 	  	 	 	222,808	  	 		 	
										
		 	9950.00	 				 		 	 MISC. FINISHES
	 				 				 				 		 	
		 		 	 	9950.50	  	 		 	 Misc. Finishes
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Finish Protection
	 	 	40,000.00 sf 	  	 	 	0.75 /sf 	  	 	 	30,000	  	 		 	
		 		 				 	Manufacturing	 	 Temp Openings for Equipment Move in
	 	 	1.00 ls 	  	 	 	10,000.00 /ls 	  	 	 	10,000	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Misc. Finishes
	 				 	 	/sf 	  	 	 	40,000	  	 		 	
		 		 				 		 	 MISC. FINISHES
	 				 	 	/sf 	  	 	 	40,000	  	 		 	
										
		 	9999.00	 				 		 	 SUPPORT & CONTROL
	 				 				 				 		 	
		 		 	 	9999.10	  	 		 	 Supervision
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Foreman
	 	 	1,393.60 hr 	  	 	 	78.00 /hr 	  	 	 	108,701	  	 		 	
		 		 				 	Manufacturing	 	 Overtime / Offhours Allowance
	 	 	hr 	  	 	 	/hr 	  	 				 	Excluded, Not Required	 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Supervision
	 				 	 	/sf 	  	 	 	108,701	  	 		 	
										
		 		 	 	9999.60	  	 		 	 Clean Up
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Final Clean
	 	 	40,000.00 sf 	  	 	 	0.35 /sf 	  	 	 	14,000	  	 		 	
		 		 				 	Manufacturing	 	 Protocol Level 2 Clean Up
	 	 	40,000.00 sf 	  	 	 	0.50 /sf 	  	 	 	20,000	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Clean Up
	 				 	 	/sf 	  	 	 	34,000	  	 		 	
		 		 				 		 	 SUPPORT & CONTROL
	 				 	 	/sf 	  	 	 	142,701	  	 		 	
										
		 	10000.00	 				 		 	 SPECIALTIES
	 				 				 				 		 	
		 		 	 	10100.00	  	 		 	 Visual Display Boards
	 				 				 				 		 	

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 9
 Revision 2
 3/11/2008

 
  
  

																											
	 Location
	 	Group	 	Phase	 	 	Location	 	 Description
	 	Quantity	 	 	Total Cost/Unit	 	 	Total
Amount	 	 	 Notes / Comments
	 	CSI
		 		 	 	10100.00	  	 		 	 Visual Display Boards
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Whiteboards
	 	 	ea 	  	 	 	/ea 	  	 				 	By Revance	 	
										
		 		 	 	10160.00	  	 		 	 Toilet Partitions
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Toilet Partitions & Urinal Screens
	 	 	0.00 ea 	  	 	 	0.00 /ea 	  	 	 	0	  	 	Existing, No New Scope	 	
										
		 		 	 	10185.00	  	 		 	 Shower/Dressing Compart
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Shower / Dressing Compartments
	 	 	4.00 ea 	  	 	 	750.00 /ea 	  	 	 	3,000	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Shower/Dressing Compart
	 				 	 	/sf 	  	 	 	3,000	  	 		 	
										
		 		 	 	10260.00	  	 		 	 Wall & Corner Guards
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Corner Guards
	 	 	39.00 ea 	  	 	 	250.00 /ea 	  	 	 	9,750	  	 		 	
		 		 				 	Manufacturing	 	 PVC Wall Protection
	 	 	4,061.50 sf 	  	 	 	8.00 /sf 	  	 	 	32,492	  	 	Along corridors only	 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Wall & Corner Guards
	 				 	 	/sf 	  	 	 	42,242	  	 		 	
										
		 		 	 	10345.00	  	 		 	 Projection Screens
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Projection Screens, Manual
	 	 	ea 	  	 	 	/ea 	  	 				 	By Revance	 	
										
		 		 	 	10435.00	  	 		 	 Signs and Letters
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Interior Signage at Doors
	 	 	Revisions 2 	  	 	 	/ls 	  	 				 	Existing, No New Scope	 	
										
		 		 	 	10500.00	  	 		 	 Lockers & Benches
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Double Lockers
	 	 	11.00 ea 	  	 	 	450.00 /ea 	  	 	 	4,950	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Lockers & Benches
	 				 	 	/sf 	  	 	 	4,950	  	 		 	
										
		 		 	 	10520.00	  	 		 	 Fire Extinguishers Etc
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 FEC’s
	 	 	4.00 ea 	  	 	 	500.00 /ea 	  	 	 	2,000	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Fire Extinguishers Etc
	 				 	 	/sf 	  	 	 	2,000	  	 		 	
										
		 		 	 	10605.00	  	 		 	 Wire Mesh Partitions
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 12’-10” High Fencing
	 	 	165.00 lf 	  	 	 	110.00 /lf 	  	 	 	18,150	  	 		 	
		 		 				 	Manufacturing	 	 8’ Slider Gate, 8’ Wide
	 	 	4.00 ea 	  	 	 	1,800.00 /ea 	  	 	 	7,200	  	 		 	
		 		 				 	Manufacturing	 	 Double Gate Door, 6080 with panic hardware
	 	 	1.00 ea 	  	 	 	900.00 /ea 	  	 	 	900	  	 		 	
		 		 				 	Manufacturing	 	 10’ High Fencing/Cages between Pallet Racks
	 	 	260.00 lf 	  	 	 	90.00 /lf 	  	 	 	23,400	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Wire Mesh Partitions
	 				 	 	/sf 	  	 	 	49,650	  	 		 	
										
		 		 	 	10670.00	  	 		 	 Storage Shelving
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Storage Shelving
	 	 	1.00 ls 	  	 	 	25,000.00 /ls 	  	 	 	25,000	  	 	Allowance at Cold Room & Quarantine	 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Storage Shelving
	 				 	 	/sf 	  	 	 	25,000	  	 		 	
										
		 		 	 	10750.00	  	 		 	 Misc. Specialties
	 				 				 				 		 	
		 		 				 	Manufacturing	 	 Gowning Room Accessories
	 	 	9.00 ea 	  	 	 	5,000.00 /ea 	  	 	 	45,000	  	 		 	
		 		 				 		 		 				 				 	  
	  
	 	 		 	
		 		 				 		 	 Misc. Specialties
	 				 	 	/sf 	  	 	 	45,000	  	 		 	

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 10
 Revision 2
 3/11/2008

 
  
  

																													
	 Location
	 	Group	 	 	Phase	 	 	Location	 	 Description
	 	Quantity	 	 	Total Cost/Unit	 	 	Total
Amount	 	  	 Notes / Comments
	  	CSI
		 				 				 		 	 SPECIALTIES
	 				 	 	/sf 	  	 	 	171,842	  	  		  	
										
		 	 	11000.00	  	 				 		 	 EQUIPMENT
	 				 				 				  		  	
		 				 	 	11160.00	  	 		 	 Equip: Dock
	 				 				 				  		  	
		 				 				 	Manufacturing	 	 Dock Leveler
	 	 	ea 	  	 	 	/ea 	  	 				  	NIC	  	
										
		 				 	 	11600.00	  	 		 	 Equip: Laboratory
	 				 				 				  		  	
		 				 				 	Manufacturing	 	 Scullery Sinks, Fume Hoods
	 	 	40,000.00 sf 	  	 	 	3.75 /sf 	  	 	 	150,000	  	  	Assumed same equipment as Paseo Padre	  	
		 				 				 	Manufacturing	 	 Laboratory Casework
	 	 	400.00 lf 	  	 	 	500.00 /lf 	  	 	 	200,000	  	  	Conceptual ROM based on $/SF	  	
		 				 				 	Manufacturing	 	 Lab Equipment
	 	 	40,000.00 sf 	  	 	 	/sf 	  	 				  	Revance to provide Lab Equip	  	
		 				 				 		 		 				 				 	  
	  
	 	  		  	
		 				 				 		 	 Equip: Laboratory
	 				 	 	/sf 	  	 	 	350,000	  	  		  	
		 				 				 		 	 EQUIPMENT
	 				 	 	/sf 	  	 	 	350,000	  	  		  	
										
		 	 	12000.00	  	 				 		 	 FURNISHINGS
	 				 				 				  		  	
		 				 	 	12324.00	  	 		 	 Trim/Misc
	 				 				 				  		  	
		 				 				 	Manufacturing	 	 SS Trim at Equipment
	 	 	2,200.00 sf 	  	 	 	25.00 /sf 	  	 	 	55,000	  	  	Conceptual ROM based on $/SF	  	
		 				 				 		 		 				 				 	  
	  
	 	  		  	
		 				 				 		 	 Trim/Misc
	 				 	 	/sf 	  	 	 	55,000	  	  		  	
										
		 				 	 	12490.00	  	 		 	 Window Treatment
	 				 				 				  		  	
		 				 				 	Manufacturing	 	 Horizontal Louver Blinds Repair at Ext Windows
	 	 	4,500.00 sf 	  	 	 	0.67 /sf 	  	 	 	3,000	  	  	Allowance	  	
		 				 				 	Manufacturing	 	 Mecho Shades
	 	 	0.00 sf 	  	 	 	0.00 /sf 	  	 	 	0	  	  	Excluded	  	
		 				 				 		 		 				 				 	  
	  
	 	  		  	
		 				 				 		 	 Window Treatment
	 				 	 	/sf 	  	 	 	3,000	  	  		  	
		 				 				 		 	 FURNISHINGS
	 				 	 	/sf 	  	 	 	58,000	  	  		  	
										
		 	 	13000.00	  	 				 		 	 SPECIAL CONSTRUCTION
	 				 				 				  		  	
		 				 	 	13030.00	  	 		 	 Clean Rooms
	 				 				 				  		  	
		 				 				 	Manufacturing	 	 Clean Protocol Supplies / Booties / Hairnets / Temp Gowning
	 	 	1.00 ls 	  	 	 	/ls 	  	 				  	Materials to be provided by Revance for GMP Protocol Level 2	  	
		 				 				 	Manufacturing	 	 GMP Protocol Supervision
	 	 	240.00 hrs 	  	 	 	92.00 /hrs 	  	 	 	22,080	  	  		  	
		 				 				 		 		 				 				 	  
	  
	 	  		  	
		 				 				 		 	 Clean Rooms
	 				 	 	/sf 	  	 	 	22,080	  	  		  	
										
		 				 	 	13035.00	  	 		 	 Cold Storage Rooms
	 				 				 				  		  	
		 				 				 	Manufacturing	 	 Cold Storage Room – Conceptual
	 	 	80.00 sf 	  	 	 	500.00 /sf 	  	 	 	40,000	  	  	Process Cold Room, ISO 8	  	
		 				 				 	Manufacturing	 	 Cold Storage Room – Conceptual
	 	 	sf 	  	 	 	/sf 	  	 				  	Excluded; Future Cost: 185,700	  	
		 				 				 		 		 				 				 	  
	  
	 	  		  	
		 				 				 		 	 Cold Storage Rooms
	 				 	 	/sf 	  	 	 	40,000	  	  		  	
		 				 				 		 	 SPECIAL CONSTRUCTION
	 				 	 	/sf 	  	 	 	62,080	  	  		  	
										
		 	 	14000.00	  	 				 		 	 CONVEYING SYSTEMS
	 				 				 				  		  	
		 				 	 	14040.00	  	 		 	 Hoists & Cranes
	 				 				 				  		  	

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 11
 Revision 2
 3/11/2008

 
  
  

																													
	 Location
	 	Group	 	 	Phase	 	 	Location	 	 Description
	 	Quantity	 	 	Total Cost/Unit	 	 	Total
Amount	 	 	 Notes / Comments
	 	CSI
		 				 	 	14040.00	  	 		 	 Hoists & Cranes
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Hoist Industrial Heavy Duty
	 	 	1.00 ea 	  	 	 	/ea 	  	 				 		 	
										
		 	 	15000.00	  	 				 		 	 MECHANICAL SYSTEMS
	 				 				 				 		 	
		 				 	 	15300.00	  	 		 	 Fire Protection
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Fire Protection Modifications
	 	 	40,000.00 sf 	  	 	 	3.00 /sf 	  	 	 	120,000	  	 		 	
		 				 				 	Manufacturing	 	 Fire Protection at Service Yard
	 	 	0.00 sf 	  	 	 	/sf 	  	 				 	Excluded, No Canopy at New Service Yard	 	
		 				 				 	Manufacturing	 	 Fire Pump
	 	 	sf 	  	 	 	/sf 	  	 				 	Excluded, Not Required	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Fire Protection
	 				 	 	/sf 	  	 	 	120,000	  	 		 	
										
		 				 	 	15310.00	  	 		 	 Special FP Systems
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 PreAction Modifications to Office Server Room
	 	 	ls 	  	 	 	/ls 	  	 				 	Excluded, Not Required	 	
		 				 				 	Manufacturing	 	 Foam System
	 	 	sf 	  	 	 	/sf 	  	 				 	Excluded, Not Required	 	
										
		 				 	 	15450.00	  	 		 	 Process Piping
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Gas Line Upgrade to Medium Pressure
	 	 	0.00 sf 	  	 	 	/sf 	  	 				 	Exclude, Piping should not change	 	
		 				 				 	Manufacturing	 	 Process / Plumbing Piping – Conceptual
	 	 	40,000.00 sf 	  	 	 	148.38 /sf 	  	 	 	5,935,200	  	 	Per Paseo Padre Bid	 	
		 				 				 	Manufacturing	 	 Process / Plumbing Piping – Conceptual
	 	 	–40,000.00 sf 	  	 	 	43.38 /sf 	  	 	 	(1,735,200	) 	 	Reduced unit cost for larger bldg SF & loss GMP area	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Process Piping
	 				 	 	/sf 	  	 	 	4,200,000	  	 		 	
										
		 				 	 	15500.00	  	 		 	 HVAC Systems
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 HVAC Systems – Equipment & Distribution
	 	 	40,000.00 sf 	  	 	 	205.00 /sf 	  	 	 	8,200,000	  	 	Per Paseo Padre Bid	 	
		 				 				 	Manufacturing	 	 Adjusted Cooling Capacity
	 	 	–160.00 tons 	  	 	 	1,000.00 /tons 	  	 	 	(160,000	) 	 		 	
		 				 				 	Manufacturing	 	 Eliminate Cooling Towers Assembly
	 	 	–1.00 ls 	  	 	 	107,000.00 /ls 	  	 	 	(107,000	) 	 		 	
		 				 				 	Manufacturing	 	 Modify (E) AC for Server Room
	 	 	–1.00 ls 	  	 	 	7,500.00 /ls 	  	 	 	(7,500	) 	 		 	
		 				 				 	Manufacturing	 	 Delete AHU5 since (E) DX Units can serve Manufacturing
	 	 	–1.00 ea 	  	 	 	35,000.00 /ea 	  	 	 	(35,000	) 	 		 	
		 				 				 	Manufacturing	 	 Increase AHU 3 by 10,000 CFM
	 	 	10,000.00 cfm 	  	 	 	7.49 /cfm 	  	 	 	74,900	  	 		 	
		 				 				 	Manufacturing	 	 Steam to Water Heat Exchanger to Provide Hot Water for preheat and reheat coils
	 	 	40,000.00 sf 	  	 	 	/sf 	  	 				 	Included in $/SF Price above	 	
		 				 				 	Manufacturing	 	 Reduce Cost / SF for Increased Facility Size
	 	 	–40,000.00 sf 	  	 	 	16.64 /sf 	  	 	 	(665,400	) 	 	Economy of Scale Discount	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 HVAC Systems
	 				 	 	/sf 	  	 	 	7,300,000	  	 		 	
										
		 				 	 	15900.00	  	 		 	 Air Balancing
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Air Balancing
	 	 	40,000.00 sf 	  	 	 	/sf 	  	 				 	Included with 15.500	 	
										
		 				 	 	15910.00	  	 		 	 Mechanical/Process Cont
	 				 				 				 		 	

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 12
 Revision 2
 3/11/2008

 
  
  

																													
	 Location
	 	 Group
	 	 	Phase	 	 	Location	 	 Description
	 	Quantity	 	 	Total Cost/Unit	 	 	Total
Amount	 	 	 Notes / Comments
	 	CSI
		 				 	 	15910.00	  	 		 	 Mechanical / Process Cont
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 HVAC Controls
	 	 	40,000.00 sf 	  	 	 	15.74 /sf 	  	 	 	629,600	  	 	Based on new site per point	 	
		 				 				 	Manufacturing	 	 HVAC Controls – Equipment Monitoring Points
	 	 	40,000.00 sf 	  	 	 	3.25 /sf 	  	 	 	130,000	  	 	Per Siemens	 	
		 				 				 	Manufacturing	 	 Process Controls
	 	 	40,000.00 sf 	  	 	 	/sf 	  	 				 	Excluded, Local Control Only	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Mechanical / Process Cont
	 				 	 	/sf 	  	 	 	759,600	  	 		 	
										
		 				 	 	15920.00	  	 		 	 Clean Room Cert
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Clean Room Certification
	 	 	ls 	  	 	 	/ls 	  	 				 	By Revance	 	
										
		 				 	 	15940.00	  	 		 	 Validation
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Validation
	 	 	ls 	  	 	 	/ls 	  	 				 	NIC, Validation Documentation by MEP Trades	 	
		 				 				 		 	 MECHANICAL SYSTEMS
	 				 	 	/sf 	  	 	 	12,379,600	  	 		 	
										
		 	 	16000.00	  	 				 		 	 ELECTRICAL
	 				 				 				 		 	
		 				 	 	16001.00	  	 		 	 Electrical
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Electrical & Fire Alarm Conceptual
	 	 	40,000.00 sf 	  	 	 	39.58 /sf 	  	 	 	1,583,200	  	 		 	
		 				 				 	Manufacturing	 	 Electrical Generator, 350KW
	 	 	1.00 ea 	  	 	 	80,288.00 /ea 	  	 	 	80,288	  	 		 	
		 				 				 	Manufacturing	 	 Removal of Feeds thru Bldg 2 MPOE to Other Buildings
	 	 	1.00 ea 	  	 	 	/ea 	  	 				 	By Owner	 	
		 				 				 	Manufacturing	 	 Deduct for (E) Conditions
	 	 	–40,000.00 sf 	  	 	 	3.50 /sf 	  	 	 	(140,000	) 	 	Economy of Scale Discount	 	
		 				 				 	Manufacturing	 	 350 KVA ATS
	 	 	1.00 ea 	  	 	 	12,000.00 /ea 	  	 	 	12,000	  	 		 	
		 				 				 	Manufacturing	 	 150 KVA UPS for Server Room
	 	 	1.00 ea 	  	 	 	/ea 	  	 				 	By Revance	 	
		 				 				 	Manufacturing	 	 Upgrade of 3000 AMP Switchboard
	 	 	1.00 ea 	  	 	 	/ea 	  	 				 	Excluded, Not Required	 	
		 				 				 	Manufacturing	 	 Installation of New PG&E Meter
	 	 	1.00 ea 	  	 	 	/ea 	  	 				 	Excluded, By PG&E	 	
		 				 				 	Manufacturing	 	 (E) Gear Deduct
	 	 	–40,000.00 sf 	  	 	 	2.50 /sf 	  	 	 	(100,000	) 	 	Excluded, By PG&E	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Electrical
	 				 	 	/sf 	  	 	 	1,435,488	  	 		 	
										
		 				 	 	16020.00	  	 		 	 Temporary Electric
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Temporary Electric, Light and Power
	 	 	40,000.00 sf 	  	 	 	1.50 /sf 	  	 	 	60,000	  	 		 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Temporary Electric
	 				 	 	/sf 	  	 	 	60,000	  	 		 	
		 				 				 		 	 ELECTRICAL
	 				 	 	/sf 	  	 	 	1,495,488	  	 		 	
										
		 	 	17000.00	  	 				 		 	 BLDG MGMNT & SPECL SYS
	 				 				 				 		 	
		 				 	 	17001.00	  	 		 	 Security Systems
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Security System Conduits
	 	 	26,830.00 sf 	  	 	 	/sf 	  	 				 	Included in Div 16	 	
		 				 				 	Manufacturing	 	 Security System Equipment & Cameras
	 	 	26,830.00 sf 	  	 	 	26.09 /sf 	  	 	 	700,000	  	 	Per Revance	 	

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

					
	

	 	 Estimate Detail Report
 Revance Therapeutics
 Conceptual ROM Estimate
	 	 Page 13
 Revision 2
 3/11/2008

 
  
  

 

																													
	 Location
	 	Group	 	 	Phase	 	 	Location	 	 Description
	 	Quantity	 	 	Total Cost/
Unit	 	 	Total
Amount	 	 	 Notes / Comments
	 	CSI
		 				 				 		 	 Security Systems
	 				 	 	/sf	  	 	 	700,000	  	 		 	
		 				 				 		 	 BLDG MGMNT & SPECL SYS
	 				 	 	/sf	  	 	 	700,000	  	 		 	
										
		 	 	25000.00	  	 				 		 	 GENERAL REQUIREMENTS
	 				 				 				 		 	
		 				 	 	25061.00	  	 		 	 Preconstruction Services
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Preconstruction Services
	 	 	0.00 mo	  	 	 	0.00 /mo	  	 	 	75,710	  	 	For New Project Site Only	 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 Preconstruction Services
	 				 	 	/sf	  	 	 	75,710	  	 		 	
										
		 				 	 	25070.00	  	 		 	 GC’S: Miscellaneous
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 General Conditions
	 	 	43.00 wks	  	 	 	26,220.51 /wks	  	 	 	1,127,482	  	 		 	
		 				 				 		 		 				 				 	  
	  
	 	 		 	
		 				 				 		 	 GC’S: Miscellaneous
	 				 	 	/sf	  	 	 	1,127,432	  	 		 	
		 				 				 		 	 GENERAL REQUIREMENTS
	 				 	 	/sf	  	 	 	1,203,192	  	 		 	
										
		 	 	26000.00	  	 				 		 	 DESIGN
	 				 				 				 		 	
		 				 	 	26020.00	  	 		 	 Design Consultants
	 				 				 				 		 	
		 				 				 	Manufacturing	 	 Structural Calcs for Cold Room, Pallet Racks & Other Equipment 
	 	 	0.00 ls	  	 	 	0.00 /ls	  	 	 	0	  	 	By Owner, Soft Costs	 	
		 				 				 		 	 Manufacturing
	 				 				 	 	19,029,006	  	 		 	

 Partial Totals 
  

																															
	 Description
	  	Amount	 	  	Totals	 	  	Hours	 	  	Rate	 	 	Cost Basis	  	Cost per Unit	 	  	Percent of Total	 	 	 	 
	 Labor
	  	 	1,366,813	  	  				  	 	1,843.321 hrs	  	  				 		  	 	15.187 /sf	  	  	 	6.91	% 	 			
	 Material
	  	 	5,000	  	  				  				  				 		  	 	0.056 /sf	  	  	 	0.03	% 	 			
	 Subcontract
	  	 	17,584,193	  	  				  				  				 		  	 	195.330 /sf	  	  	 	88.96	% 	 			
	 Equipment
	  	 	73,000	  	  				  				  				 		  	 	0.811 /sf	  	  	 	0.37	% 	 			
	 Other
	  				  				  				  				 		  				  				 			
		  	  
	  
	 	  				  				  				 		  	  
	  
	 	  	  
	  
	 	 			
		  	 	19,029,065	  	  	 	19,029,006	  	  				  				 		  	 	211.433 /sf	  	  	 	96.26	  	 	 	96.26	% 
									
	 Liability Insurance
	  	 	209,319	  	  				  				  	 	1.100	% 	 	T	  	 	2.326 /sf	  	  	 	1.06	% 	 			
	 Fee
	  	 	529,054	  	  				  				  	 	2.750	% 	 	T	  	 	5.878 /sf	  	  	 	2.68	% 	 			
	 Builders Risk Insurance
	  				  				  				  				 	T	  				  				 			
	 Contigencies - See Exec Smry
	  				  				  				  				 	T	  				  				 			
	 Partial Total
	  				  	 	19,767,379	  	  				  				 		  	 	219.638 /sf	  	  				 			

  
 XL CONSTRUCTION
CORPORATION (CONFIDENTIAL) 

 ATTACHMENT 5 TO EXHIBIT B 

CONCEPTUAL PLANS 
 

 

  
 B-5-1

 

 

 ATTACHMENT 6 TO EXHIBIT B 

GENERAL CONTRACTOR MINIMUM PERFORMANCE REQUIREMENTS 
 Project Management: 
 The General Contractor shall provide the following minimum project
management team. 
 Preconstruction Phase – Part time 
  

	•	 	 Project Manager 

  

	•	 	 Estimator 

  

	•	 	 MEP Coordinator 

Construction Phase 
  

	•	 	 Project Manager – Full time 

  

	•	 	 Project Engineer – Full time 

  

	•	 	 Sr. Project Engineer – Part Time 

  

	•	 	 MEP Coordinator – Half time during construction, full time during start up 

 

	•	 	 Superintendent – Full time 

  

	•	 	 Field Office Coordinator – Full time 

 Pre-construction Phase Services: 
 The General Contractor will provide the following
services during the pre-construction phase: 
  

	•	 	 Provide general advice on budget, and constructability issues 

 

	•	 	 Prepare detailed project schedule in Prima Vera P6 or Sure Track 

 

	 	•	 	 Identify schedule critical equipment pre-purchase requirements 

 

	 	•	 	 Procurement of the equipment as necessary to meet the project schedule 

 

	 	•	 	 Prepare schedule variance reports 

  

	 	•	 	 Perform monthly updates 

  

	•	 	 Selected respondent to verify existing conditions at the project site 

 

	•	 	 Attend weekly project meetings for the interior improvements design and engineering 

 

	•	 	 Prepare cost estimates for each phase of the project 

  

	 	•	 	 Conceptual Phase – upon completion of the BOD 

  

	 	•	 	 Preliminary Design (DD) 

  

	 	•	 	 Permit Construction Documents 

  

	 	•	 	 Track and update cost estimates as key decisions are made 

 

	 	•	 	 Provide estimate variance reports defining costs changes from previous cost estimate 

 

	 	•	 	 Report budget trends as part of weekly meetings 

  

	•	 	 Complete cost studies for alternate design solutions 

  

	•	 	 Complete constructability reviews and cost analysis 

  

	•	 	 Manage the bidding of multiple construction packages and pre-purchase equipment packages 

Other Construction Requirements: 
  

	•	 	 Assist the architect with interfacing with the City on the submission of permit packages, payment of fees (to be reimbursed) and pick up of permits. It
is expected multiple permits will be required per the project phasing requirements. 

  

	 	•	 	 R&D, Manufacturing Facility, Utilities, Warehouse 

 

	 	•	 	 Seismic (owner’s equipment and subcontractor’s equipment) 

	•	 	 Following the selection of agreed upon list of subcontractor bidders, the General Contractor will receive at least three (3) bids per trade.
Prepare bid analysis, outlining areas of qualification. Discuss recommendations with the Team. 

  

	 	•	 	 Contractor to provide closed bids to be opened with Landlord & Tenant for work that the General Contractor would like bid upon (potential self
performed work) 

  

	•	 	 Prepare 5 complete sets of Turn Over Packages to the Owner (3 copies), Architect (1 copy) and the Landlord (1 copy) at the completion of the project.

  

	•	 	 Facility Turn Over Package to include: Building Inspection “Finals,” project subcontractor contact list, warranty documentation, Certificate
of Occupancy, complete and detailed as- 

  
 B-6-1

	 	 
builts drawings, O & M Manuals, training documentation, Final Lien Releases. Close-out will be completed before Final Payment is made. 

 

	•	 	 Provide commissioning and qualification support. 

  
 B-6-2

 ATTACHMENT 7 TO EXHIBIT B 

LANDLORD’S WORK 
 Landlord shall: 
  

	1.	Cause the Building to be reclassified to Type 2; 

  

	2.	Replace the Building’s roof; 

  

	3.	Repair the caulking between the EIFS and window walls; 

  

	4.	Ensure that the generator for the Building as of the Execution Date is operational; or, if it is not operational as of the Term Commencement Date, replace it with a
generator of similar or greater capacity that will satisfy the Bay Area Air Quality Management District’s emissions standards for 2010 that are in effect as of the Execution Date; 

 

	5.	Create a pathway from the parking lot to the Building lobby entrance in the general area shown on Exhibit L to the Lease, subject to the approval of the
applicable Governmental Authorities; 

  

	6.	Relocate the fiber main point of entry outside of the Building; and 

  

	7.	Install a Building electric meter. 

  
 B-7-1

 EXHIBIT C 
 ACKNOWLEDGEMENT OF TERM COMMENCEMENT DATE 
 AND TERM EXPIRATION DATE

 THIS ACKNOWLEDGEMENT OF TERM COMMENCEMENT DATE AND TERM EXPIRATION DATE is entered into as of
[            ], 20 [    ], with reference to that certain Lease (the “Lease”) dated as of March 31, 2008, by REVANCE THERAPEUTICS, INC., a Delaware
corporation (“Tenant”), in favor of BMR-Gateway Boulevard LLC, a Delaware limited liability company (“Landlord”). All capitalized terms used herein without definition shall have the meanings ascribed to them in the
Lease. 
 Tenant hereby confirms the following: 
 1. Tenant accepted possession of the Premises on [            ], 20[    ]. 

2. The Premises are in good order, condition and repair, subject to Punchlist Items. 

3. The Tenant Improvements required to be constructed by Landlord under the Lease have been substantially completed, subject to Punchlist
Items. 
 4. All conditions of the Lease to be performed by Landlord as a condition to the full effectiveness of the Lease have
been satisfied, and Landlord has fulfilled all of its duties in the nature of inducements offered to Tenant to lease the Premises. 
 5. In accordance with the provisions of Section 4.2 of the Lease, the Term Commencement Date is [            ],
20[    ], and, unless the Lease is terminated or extended prior to the Term Expiration Date pursuant to its terms, the Term Expiration Date shall be [            ],
20[    ]. 
 6. Tenant commenced occupancy of the Premises for the Permitted Use on
[            ], 20[    ]. 
 7. The Lease is in
full force and effect, and the same represents the entire agreement between Landlord and Tenant concerning the Premises [, except [            ]]. 

8. To Tenant’s knowledge, Tenant has no existing defenses against the enforcement of the Lease by Landlord, and there exist no
offsets or credits against Rent owed or to be owed by Tenant. 
 9. The obligation to pay Rent is presently in effect and all
Rent obligations on the part of Tenant under the Lease commenced to accrue on [            ], 20[    ]. 

10. The undersigned Tenant has not made any prior assignment, transfer, hypothecation or pledge of the Lease or of the rents thereunder
or sublease of the Premises or any portion thereof. 
 [REMAINDER OF THIS PAGE INTENTIONALLY LEFT BLANK] 

  
 C-1

 IN WITNESS WHEREOF, the parties hereto have executed this Acknowledgment of Term
Commencement Date and Term Expiration Date as of the date first written above. 
  

			
	TENANT:
	
	REVANCE THERAPEUTICS, INC., a Delaware corporation
		
	By:	 	  

	Name:	 	  

	Title:	 	  

  
 C-2

 EXHIBIT D 
 FORM OF ADDITIONAL TI COSTS/EXCESS TI COSTS ACCEPTANCE LETTER 

[TENANT LETTERHEAD] 

BMR-Gateway Boulevard LLC 
 17140 Bernardo
Center Drive, Suite 222 
 San Diego, California 92128 
 Attn: General Counsel/Real Estate 
 [Date] 

 

	 	Re:	Additional TI Costs/Excess TI Costs 

 To
Whom It May Concern: 
 This letter concerns that certain Lease dated as of March 31, 2008 (the “Lease”),
between BMR-Gateway Boulevard LLC (“Landlord”) and Revance Therapeutics, Inc. (“Tenant”). Capitalized terms not otherwise defined herein shall have the meanings given them in the Lease. 

Tenant hereby notifies Landlord that it wishes to exercise its right to incur Additional TI Costs/Excess TI Costs pursuant to
Section 4.4 of the Lease. 
 If you have any questions, please do not hesitate to call
[            ] at ([        ]) [        ]-[        ]. 

 

	
	Sincerely,
	
	[Name]
	[Title of Authorized Signatory]

  

			
	cc:	  	Greg Lubushkin
		  	John Wilson
		  	Kevin Simonsen

  
 D-1

 EXHIBIT E 
 FORM OF LETTER OF CREDIT 
 [On letterhead or L/C letterhead of
Issuer.] 
 LETTER OF CREDIT 
 Date:             , 200     
  

					
	  
	 	(the “Beneficiary”)
	  
	 	
	  
	 	
	Attention:	 	  
	 	
	L/C. No.:	 	  
	 	
	Loan No.:	 	  
	 	

 Ladies and Gentlemen: 
 We establish in favor of Beneficiary our irrevocable and unconditional Letter of Credit numbered as identified above (the “L/C”) for an aggregate amount of
$        , expiring at     :00 p.m. on              or, if such day is not a Banking Day, then the next succeeding Banking Day
(such date, as extended from time to time, the “Expiry Date”). “Banking Day” means a weekday except a weekday when commercial banks in
                             are authorized or required to close. 

We authorize Beneficiary to draw on us (the “Issuer”) for the account of
                     (the “Account Party”), under the terms and conditions of this L/C. 

Funds under this L/C are available by presenting the following documentation (the “Drawing Documentation”): (a) the
original L/C and (b) a sight draft substantially in the form of Exhibit 1, with blanks filled in and bracketed items provided as appropriate. No other evidence of authority, certificate, or documentation is required. 

Drawing Documentation must be presented at Issuer’s office at
                             on or before the Expiry Date by personal presentation, courier or messenger
service, or fax. Presentation by fax shall be effective upon electronic confirmation of transmission as evidenced by a printed report from the sender’s fax machine. After any fax presentation, but not as a condition to its effectiveness,
Beneficiary shall with reasonable promptness deliver the original Drawing Documentation by any other means. Issuer will on request issue a receipt for Drawing Documentation. 
 We agree, irrevocably, and irrespective of any claim by any other person, to honor drafts drawn under and in conformity with this L/C, within the maximum amount of this L/C, presented to us on or before
the Expiry Date, provided we also receive (on or before the Expiry Date) any other Drawing Documentation this L/C requires. 
 We shall pay this L/C only from our own funds by check or wire transfer, in compliance with the Drawing Documentation. 
 If Beneficiary presents proper Drawing Documentation to us on or before the Expiry Date, then we shall pay under this L/C at or before the following time (the “Payment Deadline”):
(a) if presentment is made at or before noon of any Banking Day, then the close of such Banking Day; and (b) otherwise, the close of the next Banking Day. We waive any right to delay payment beyond the Payment Deadline. If we determine
that Drawing Documentation is not proper, then we shall so advise Beneficiary in writing, specifying all grounds for our determination, within one Banking Day after the Payment Deadline. 

Partial drawings are permitted. This L/C shall, except to the extent reduced thereby, survive any partial drawings. 

  
 E-1

 We shall have no duty or right to inquire into the validity of or basis for any draw under
this L/C or any Drawing Documentation. We waive any defense based on fraud or any claim of fraud. 
 The Expiry Date shall
automatically be extended by one year (but never beyond              the “Outside Date”) unless, on or before the date 90 days before any Expiry Date, we have given
Beneficiary notice that the Expiry Date shall not be so extended (a “Nonrenewal Notice”). We shall promptly upon request confirm any extension of the Expiry Date under the preceding sentence by issuing an amendment to this L/C, but
such an amendment is not required for the extension to be effective. We need not give any notice of the Outside Date. 

Beneficiary may from time to time without charge transfer this L/C, in whole but not in part, to any transferee (the
“Transferee”). Issuer shall look solely to Account Party for payment of any fee for any transfer of this L/C. Such payment is not a condition to any such transfer. Beneficiary or Transferee shall consummate such transfer by
delivering to Issuer the original of this L/C and a Transfer Notice substantially in the form of Exhibit 2, purportedly signed by Beneficiary, and designating Transferee. Issuer shall promptly reissue or amend this L/C in favor of Transferee
as Beneficiary. Upon any transfer, all references to Beneficiary shall automatically refer to Transferee, who may then exercise all rights of Beneficiary. Issuer expressly consents to any transfers made from time to time in compliance with this
paragraph. 
 Any notice to Beneficiary shall be in writing and delivered by hand with receipt acknowledged or by overnight
delivery service such as FedEx (with proof of delivery) at the above address, or such other address as Beneficiary may specify by written notice to Issuer. A copy of any such notice shall also be delivered, as a condition to the effectiveness of
such notice, to:                      (or such replacement as Beneficiary designates from time to time by written notice). 

No amendment that adversely affects Beneficiary shall be effective without Beneficiary’s written consent. 

This L/C is subject to and incorporates by reference: (a) the Uniform Customs and Practice for Documentary Credits, International
Chamber of Commerce Publication No. 500 (the “UCP”); and (b) to the extent not inconsistent with the UCP, Article 5 of the Uniform Commercial Code of the State of New York. 

 

					
		  	Very truly yours,	 	
			
		  	[Issuer Signature]	 	

  
 E-2

 EXHIBIT 1 TO EXHIBIT E 

FORM OF SIGHT DRAFT 
 [BENEFICIARY LETTERHEAD] 
 TO: 

[Name and Address of Issuer] 

SIGHT DRAFT 
 AT SIGHT,
pay to the Order of                     , the sum of
                     United States Dollars ($            ). Drawn under [Issuer] Letter
of Credit No.                      dated
                    . 
 [Issuer is hereby
directed to pay the proceeds of this Sight Draft solely to the following account:                     .] 

[Name and signature block, with signature or purported signature of Beneficiary] 
 Date:                      

  
 E-3

 EXHIBIT 2 TO EXHIBIT E 

FORM OF TRANSFER NOTICE 
 [BENEFICIARY LETTERHEAD] 
 TO: 

[Name and Address of Issuer] (the “Issuer”) 
 TRANSFER NOTICE 
 By signing below, the undersigned, Beneficiary (the
“Beneficiary”) under Issuer’s Letter of Credit No.                      dated
                     (the “L/C”), transfers the L/C to the following transferee (the “Transferee”): 

[Transferee Name and Address] 
 The original
L/C is enclosed. Beneficiary directs Issuer to reissue or amend the L/C in favor of Transferee as Beneficiary. Beneficiary represents and warrants that Beneficiary has not transferred, assigned, or encumbered the L/C or any interest in the L/C,
which transfer, assignment, or encumbrance remains in effect. 
 [Name and signature block, with signature or purported signature of
Beneficiary] 
 Date:                     

  
 E-4

 EXHIBIT F 
 RULES AND REGULATIONS 
 NOTHING IN THESE RULES AND REGULATIONS (“RULES AND
REGULATIONS”) SHALL SUPPLANT ANY PROVISION OF THE LEASE. IN THE EVENT OF A CONFLICT OR INCONSISTENCY BETWEEN THESE RULES AND REGULATIONS AND THE LEASE, THE LEASE SHALL PREVAIL. 

1. Except as specifically provided in the Lease to which these Rules and Regulations are attached, no sign, placard, picture,
advertisement, name or notice shall be installed or displayed on any part of the outside of the Building without Landlord’s prior written consent. Landlord shall have the right to remove, at Tenant’s sole cost and expense and without
notice, any sign installed or displayed in violation of this rule. 
 2. If Landlord objects in writing to any curtains, blinds,
shades, screens or hanging plants or other similar objects attached to or used in connection with any window or door of the Premises or placed on any windowsill, which window, door or windowsill is (a) visible from the exterior of the Premises
and (b) not included in plans approved by Landlord, then Tenant shall promptly remove said curtains, blinds, shades, screens or hanging plants or other similar objects at its sole cost and expense. 

3. Tenant shall not obstruct any sidewalks or entrances to the Building, or any halls, passages, exits, entrances or stairways within the
Premises, in any case that are required to be kept clear for health and safety reasons. 
 4. No deliveries shall be made that
impede or interfere with other tenants in or the operation of the Project. 
 5. Tenant shall not place a load upon any floor of
the Premises that exceeds the load per square foot that (a) such floor was designed to carry or (b) that is allowed by Applicable Laws. 
 6. Tenant shall not use any method of heating or air conditioning other than that shown in the Tenant Improvement plans. 
 7. Tenant shall not install any radio, television or other antenna, cell or other communications equipment, or any other devices on the roof or exterior walls of the Premises except to the extent shown on
approved Tenant Improvements plans. Tenant shall not interfere with radio, television or other communications from or in the Premises or elsewhere. 
 8. Canvassing, peddling, soliciting and distributing handbills or any other written material within, on or around the Project (other than within the Premises) are prohibited, and Tenant shall cooperate to
prevent such activities. 
 9. Tenant shall store all of its trash, garbage and Hazardous Materials within its Premises or in
designated receptacles outside of the Premises. Tenant shall not place in any such receptacle any material that cannot be disposed of in the ordinary and customary manner of trash, garbage and Hazardous Materials disposal. 

10. The Premises shall not be used for any improper, immoral or objectionable purpose. No cooking shall be done or permitted on the
Premises; provided, however, that Tenant may use (a) equipment approved in accordance with the requirements of insurance policies that Landlord or Tenant is required to purchase and maintain pursuant to the Lease for brewing coffee, tea,
hot chocolate and similar beverages, (b) microwave ovens for employees’ use and (c) equipment shown on Tenant Improvement plans approved by Landlord; provided, further, that any such equipment and microwave ovens are used in
accordance with Applicable Laws. 
 11. Tenant shall not, without Landlord’s prior written consent, use the name of the
Project, if any, in connection with or in promoting or advertising Tenant’s business except as Tenant’s address. 

  
 F-1

 12. Tenant shall comply with all safety, fire protection and evacuation procedures and
regulations established by Landlord or any Governmental Authority. 
 13. Tenant assumes any and all responsibility for
protecting the Premises from theft, robbery and pilferage, which responsibility includes keeping doors locked and other means of entry to the Premises closed. 
 14. Landlord may waive any one or more of these Rules and Regulations for the benefit of Tenant or any other tenant, but no such waiver by Landlord shall be construed as a waiver of such Rules and
Regulations in favor of Tenant or any other tenant, nor prevent Landlord from thereafter enforcing any such Rules and Regulations against any or all of the tenants of the Project, including Tenant. 

15. These Rules and Regulations are in addition to, and shall not be construed to in any way modify or amend, in whole or in part, the
terms covenants, agreements and conditions of the Lease. 
 16. Landlord reserves the right to make such other and reasonable
rules and regulations as, in its judgment, may from time to time be needed for safety and security, the care and cleanliness of the Project, or the preservation of good order therein; provided, however, that Landlord shall provide written
notice to Tenant of such rules and regulations prior to them taking effect. Tenant agrees to abide by these Rules and Regulations and any additional rules and regulations issued or adopted by Landlord. 

17. Tenant shall be responsible for the observance of these Rules and Regulations by Tenant’s employees, agents, clients, customers,
invitees and guests. 

  
 F-2

 EXHIBIT G 
 HAZARDOUS MATERIALS LIST 
  

			
	Chemical Inventory	  	updated 12/06
		
	 NAME
	  	 CAS NO.

	Acetic anhydride	  	108-24-7
	acetic acid glacial	  	64-19-7
	Acetone	  	67-64-1
	acetonitirile 99%	  	75-05-8
	Acetylcholinesterase human	  	9000-81-1
	Acridine orange	  	494-38-2
	acridinium NHS ester	  	N/A
	Acrylamide	  	79-06-1
	30% acrylamide	  	79-06-1
	Agarose	  	39346-81-1
	ajidew NL-50 (sodium salt pyrrolidone carboxylic acid)	  	N/A
	albumin bovine serum	  	9048-46-8
	aldehyde activated dextran coupling kit	  	25895-60-7
	alprenolol hydrochloride	  	13707-88-5
	aluminum sulfate, hydrate	  	17927-65-0
	Aminoethanol	  	141-43-5
	ammonium acetate	  	631-61-8
	ammonium bicarbonate	  	1066-33-7
	ammonium heptamolybdate tetrahydrate	  	12054-85-2
	ammonium hydroxide	  	1336-21-6
	ammonium persulfate	  	7727-54-0
	ammonium persulfite	  	7727-54-0
	ammonium sulfate	  	7783-20-2
	amphotecirin-B	  	
	Ampicillan	  	69-53-4
	Amyl alcohol	  	123-51-3
	angiopoietin-2 human recombinant	  	mixture, 90-48-46-8
	aquadew spa-30 (sodium polyaspartate solution)	  	94525-01-6
	Arg-OH	  	N/A
	Artemisinin	  	63968-64-9
	ascorbic acid (liquid)	  	50-81-7
	ascorbic acid (solid)	  	50-81-7
	Atropine	  	51-55-8
	Avidin	  	1405-69-2
	Bactoagar	  	9002-18-0
	Bactopepetone	  	147-85-3
	Benzalkonium chloride	  	8001-54-5
	benzamidine hydrochloride hydrate	  	1670-14-0
	benzoyl peroxide	  	94-36-0
	benzyl alcohol	  	N/A
	Benzylamine	  	100-46-3
	Benzyl-2-bromoacetate 96%	  	5497-45-6
	benzyl bromoacetate 96%	  	5437-45-6
	Betamethasone 17,21-dipro	  	5593-20-4
	EZ-linkSulfo-NHS-LC-Biotin	  	127062-22-0
	EZ-Link NHS-LC-Biotin	  	72040-63-2
	D-Biotin	  	58-85-5
	Bis-tris	  	6976-37-0
	blue dextran	  	87915-38-6

  
 G-1

			
	Boc-Asp-Osu	  	13798-75-9
	N-Boc-Ethylenediamine	  	57260-73-8
	Boric acid	  	10043-35-3
	Botox	  	N/A
	bovine serum albumin	  	N/A
	brilliant cresol blue	  	4712-70-3
	Bromocresol green	  	62625-32-5
	2-bromoethylene HBr	  	N/A
	bromophenol blue	  	115-39-9
	2-butanone	  	78-93-3
	Butoxycarbonyl-o-glucosamine	  	N/A
	butyl alcohol, normal	  	71-36-3
	butyl alcohol-tert	  	75-65-0
	butyl paraben	  	94-26-8
	calcium carbonate	  	471-34-1
	calcium chloride dihydrate	  	10043-52-4
	D-carnitine	  	541-14-0
	L-carnitine	  	541-15-1
	chicago sky blue 6B	  	2610-05-10
	Chitosan	  	9012764
	Chloroform	  	mixture, 67-66-3, 64-17-5
	chloroform-D	  	865-49-6
	3-Chloroperbenzoic acid	  	937-14-4
	3-chloroperoxybenzoic acid 77%	  	mixture, 937-14-4, 535-80-8, 7732-18-5
	Chloroquine	  	N/A
	chlorpromazine	  	69-09-0
	cholecalciferol crystalline	  	67-97-0
	citric acid	  	77-92-9
	clobetasol propionate	  	25122-46-7
	Concanamycin A	  	80890-47-7
	coomassie brilliant blue r-250	  	6104-59-2
	CO2	  	124-38-9
	cresol red, sodium salt	  	62625-29-0
	crystal mount	  	N/A
	cumene hydroperoxide	  	80-15-9
	cytoseal	  	N/A
	immunopure metal enhanced DAB substrate kit	  	N/A
	decamethonium bromide	  	541-22-0
	dextran sulfate sodium salt	  	9011-18-1
	Dichloromethane, anhydrous, 99.8%	  	75-09-2
	1,3-dicyclohexylcarbodimiide, 99%	  	538-75-0
	Diethylpyrocarbonate	  	1609-47-8
	diethylenetriaminepentaacetic acid	  	mixture, 67-43-6, 139-13-9
	di-tert-butyl-diethylphosphoramidite, tech., 93%	  	117924-33-1
	hitrap deae ff	  	N/A
	n,n-dicyclohexylcarbodiimide	  	538-75-0
	1,3-diisopropylcarbodiimide, 99%( solid)	  	693-13-0
	1,3-diisopropylcarbodiimide, 99% (liquid)	  	693-13-0
	N,N-diisopropyl ethylamine, redistilled, 99.5%	  	7087-68-5
	dimethyl formamide	  	68-12-2
	dimethyl sulfoxide (solid)	  	67-68-5
	dimethyl sulfoxide (liquid)	  	67-68-5
	2,2-dimethoxy-2-phenyl acetophenone	  	24650-42-8
	4-dimethyl amino pyridine	  	1122-58-3
	p-Dioxane	  	129311

  
 G-2

			
	hydrogen chloride dioxan solution	  	mixture, 123-91-1, 7647-01-0
	di-tert-butyl n,n-diethylphosphoramidite	  	117924-33-1
	di-tert-butyl n,n-diisopropylphosphoramidite	  	137348-86-8
	dithiothreitol	  	27565-41-9
	dowex mr-3 mixed bed ion-exchange resin	  	103591-11-3
	Dowex 50WXZ-200 ion exchange	  	69011-20-7
	dpph	  	1898-66-4
	n,n-dimethylformamide anhydrous, 99.8%	  	68-12-2
	drierite	  	1332-82-7
	edc	  	25952-53-8
	EDTA	  	60-06-4
	erythromycin	  	114-07-8
	estradiol, usp	  	50-28-2
	Ethanol-200 proof	  	64-17-5
	ethanolamine	  	141-43-5
	1,2 ethanedithiol	  	540-63-6
	ethyl acetate	  	141-78-6
	5-(N-Ethyl-N-isopropyl)amiloride	  	1154-25-2
	ethylenediamine	  	107-15-3
	Ethylether, anhydrous	  	60-29-7
	ethyl paraben	  	120-47-8
	exonuclease III	  	N/A
	eldew cl-301	  	N/A
	eldew sl-205	  	N/A
	ether	  	
	evan’s blue	  	314-13-6
	immunopure igG1 fab preparation kit	  	N/A
	Fast Green FCF	  	2353-45-9
	Ferrous sulfate.7H20	  	7720-78-7
	Fetal Bovine Serum	  	N/A
	Ficoll, type 400	  	26873-85-8
	fluorescein isothiocyanate	  	3326-32-7
	ez-label fitc protein labeling kit	  	N/A
	Flurox (pyridine)	  	110-86-1
	fluorescein-5-thiosemicarbazide	  	76863-28-0
	flutacasone propionate	  	80474-14-2
	formaldehyde	  	mixture, 50-00-0
	formamide	  	75-12-7
	fumaric acid	  	110-17-8
	fura 2	  	113694-64-7
	gadoliminium III chloride hexahydrate	  	13450-84-5
	gallamine triethiode	  	65-29-2
	Gelatin	  	9000-70-8
	gentamicin sulfate	  	1405-14-0
	D-glucose, anhydrous	  	50-99-7
	glucosamine HCL	  	66-84-2
	glycine	  	56-40-6
	glycerol	  	56-81-5
	grape seed extract	  	N/A
	H-gly-otbu HCL	  	27532-96-3
	guanidine hydrochloride, ultrol grade	  	50-01-1
	HBr	  	N/A
	h-asp(OBz1)-OBz1 p-tosylate	  	288-33-1
	gill’s hematoxylin #3	  	N/A
	hepes, free acid	  	7365-45-9
	hepes, potassium	  	82207-62-3
	hepes, sodium salt	  	75277-39-3
	hexanes	  	110-54-3

  
 G-3

			
	hexanoyl chloride	  	142-61-0
	in-situ hybridization detection system	  	N/A
	hydrobromic acid, 47-49%	  	10035-10-6
	hydrocortisone 17-butyrate	  	13609-67-1
	hydrochloric acid, 10-33%	  	7647-01-0
	hydrogen	  	1333-74-0
	hydrogen peroxide, 30%	  	7722-84-1
	hydroquinone	  	123-31-9
	4-hydroxybenzamide, 98%	  	619-57-9
	n-hydroxybenzotriazole	  	2592-95-2
	hydroxylamine hydrochloride	  	547011-1
	Hydroxypropyl cellulose (MW10000)	  	9004-64-2
	Hydroxysuccinimide	  	6066-82-6
	n-hydroxysulfosuccinimide	  	82436-78-0
	immunopure IgG1 digestion buffer	  	N/A
	immunopure IgG1 binding buffer	  	N/A
	immunopure IgG1 elution buffer-mild	  	N/A
	Imidoazole, 99%	  	288-32-4
	Inositol	  	87-89-8
	iodine, bead	  	7553-56-2
	iodoacetamide	  	144-48-9
	IPTG	  	367-93-1
	isopropyl alcohol, 90-100%	  	67-63-0
	isoproterenol	  	51-31-0
	Isoproterenol HCL	  	51-30-9
	Ketoconazole	  	65277-42-1
	Lactose	  	64044-51-5
	lauric acid	  	143-07-7
	lectin from canavalia ensiformis	  	N/A
	lidocaine hydrochloride	  	6108-05-0
	Lithium chloride	  	7447-41-8
	Limonene 92%	  	5989275
	L-lysine monohydrochloride	  	56-87-1
	Lutrol F68	  	
	Lutrol OP-2000	  	31394-71-5
	Magnesium acetate	  	16674-78-5
	Maleic Acid	  	110-16-7
	Malonic Acid	  	141-82-2
	mefloquine hydrochloride	  	51773-92-3
	2-Mercaptoethanol	  	60-24-2
	Methylene Chloride	  	75-09-2
	1-Methylimidazole	  	616-47-7
	methyl paraben	  	Mixture
	1-methyl-2-pyrrolidone	  	872-50-4
	2-methyl-2-propanol, anhydrous, 99.5%	  	75650
	4-methyl-piperidine	  	626-58-4
	metronidazole	  	443-48-1
	MOPS	  	1132-61-2
	Magnesium Chloride	  	7786-30-3
	Magnesium Sulfate	  	7487-88-9
	Methyl Alcohol (Methanol)	  	67-56-1
	methyl green	  	7114-03-6
	MES	  	4432-31-9
	(±)-Miconazole nitrate salt	  	22831-87-7
	Mikrosil Catalyst	  	N/A
	monodansylcadaverine	  	10121-91-2
	NBT/BCIP substrate	  	N/A
	1-step NBT/BCIP	  	N/A
	NeutrAvidin	  	N/A

  
 G-4

			
	NHS	  	
	Ni Sepharose 6 Fast Flow	  	64-17-5
	Nicotine Ditartrate	  	54-11-5
	Ninhydrin	  	485-47-2
	Nitrogen (liquid and compressed)	  	7727-37-9
	Nonfat dried milk	  	000000-30-9
	Nonidet P-40	  	9036-19-5
	Nusieve 3:1 agarose	  	N/A
	Oxalic acid	  	144-62-7
	Oxalyl Chloride	  	79-37-8
	Palladium 30% on carbon	  	7440-05-3
	Palmitoyl Chloride	  	112-07-4
	PAMAM 4,10	  	mixture, 67-56-1, 163442-67-9
	PAMAM 5,5	  	mixture, 67-56-l and no CAS # for other component
	PAMAM 6,5	  	mixture, 67-56-l and no CAS # for other component
	Pentamidine Isethionate	  	140-64-7
	Pepsin	  	9001-75-6
	Perchloric Acid	  	mixture, 64-19-7, 7601-90-3
	Periodic acid	  	10450-60-9
	Phenol red	  	34487-61-1
	Phenol, redistilled 99%	  	108-95-2
	Phenol Chloroform	  	
	phenylarsine oxide	  	637-03-6
	phenylmethyl sulfonyl fluoride	  	329-98-6
	Phosphomolybdic Acid Reagent	  	mixture, 64-17-5, 51429-74-7
	85% phosphoric acid	  	7664-38-2
	Phosphomolybdic Acid Hydrate	  	51429-74-4
	Phosphorus Tribromide	  	7789-60-8
	Pilocarpine HC1	  	54-71-7
	Pipes	  	100037-69-2
	Plasmid PCMV Sport Beta-gal	  	N/A
	Poloxamer 407	  	
	Polyethylenimine, 50% WT.	  	N/A
	Polyvinylpyrolidone	  	00009003-39-8
	Polyethylene Glycol (PEG 8000)	  	25322-68-3
	Potassium Carbonate	  	584-08-7
	Potassium chloride	  	7447-40-7
	Potassium hydroxide	  	1310-58-3
	Potassium Phosphate Monobasic	  	7778-77-0
	Potassium Phosphate Dibasic	  	7758-11-4
	1,2-propanediol	  	4254-14-2
	Propylene Glycol	  	57-55-6
	Poly-l-lysine hydrobromide	  	25988-63-0
	Potassium Permanganate	  	7722-64-7
	Poly Ethylene/Vinyl Alcohol	  	N/A
	Polyphosphoric Acid-115%	  	N/A
	Ponceau S	  	6226-79-5
	2-propanol 99.5%	  	67-63-0
	Propidium iodide	  	25535-16-4
	Propranolol HC1	  	3506-09-0
	propyl paraben	  	94-13-3
	Propylene Carbonate	  	108-32-7

  
 G-5

			
	Propyl 4-hydroxybenzoate	  	94-13-3
	Pyridine, anhydrous	  	110-86-1
	Pyridine Hydrochloride	  	628-13-7
	4-Pyrrolidinopyridine	  	2456-81-7
	Qiagen Endofree Plasmid Mega Kit	  	N/A
	quinoline	  	91-22-5
	D-(+) Raffinose pentahydrate	  	17629-30-0
	Resveratrol	  	501-36-0
	trans-retinoic acid	  	302-79-4
	Salicylic Acid Sodium	  	54-21-7
	Satin Finish	  	N/A
	Sephacryl S-100	  	N/A
	Sephadex G-25	  	N/A
	Sephadex G-50	  	N/A
	Sepharose 6B	  	9012-36-6
	Silicone oil	  	63148-58-3
	Silk Powder	  	9009-99-8
	Silver Nitrate	  	7761-88-8
	Sodium Acetate	  	127-09-03
	Sodium L-ascorbate	  	134-03-2
	Sodium Bicarbonate	  	144-55-8
	Sodium Borohydride, powder, 98%	  	16940-66-2
	Sodium Chloride	  	7647-14-5
	Sodium Hydride	  	7646-69-7
	Sodium Hydroxide	  	1310-73-2
	Sodium Nitrate, ACS Reagent	  	7631-99-4
	Sodium periodate	  	7790-28-5
	Sodium Phosphate	  	7558-80-7
	Sodium Phosphate, monobasic	  	13472-35-0
	Sodium Phosphate, dibasic, dihydrate	  	7558-79-4
	Sodium salicylate	  	54-21-7
	sodium thiosulfate	  	7772-98-7
	Sorbitol	  	50-70-4
	Stachyose hydrate	  	10094-58-3
	Sucrose ACS Reagent	  	57-50-1
	Sulfur Trioside Pyridine Complex	  	26412-87-3
	Sulfuric Acid	  	7664-93-9
	Succinic Acid	  	110-15-6
	Succinic anhydride	  	108-30-5
	Succinylcholine chloride dihydrate	  	6101-15-1
	Sulconazole nitrate	  	61318-91-0
	Taq DNA Polymerase	  	N/A
	TEMED	  	110-18-9
	Tetrahydrofuran	  	109-99-9
	tetramethylbenzidine	  	54827-17-7
	Tetrazole	  	288-94-8
	lH-Tetrazole, 3 WT. % in acetonitrile	  	 mixture 75-05-8, 288-
 94-8

	Tetronic 1107	  	26316-40-5
	TES	  	7365-44-8
	Texas Red-Sulfonyl Chloride	  	82354-19-6
	Texas Red-X protein labeling kit	  	216972-99-5
	thioanisole	  	100-68-5
	Thionyl Chloride	  	7719-097
	Toluene	  	108-88-3
	Traut’s Reagent	  	4721-83-3
	Trehalose dihydrate	  	6138-23-4
	Triamcinolone	  	124-94-7
	Triethylamine	  	121-44-8

  
 G-6

			
	Triethanolamine (triethylolamine)	  	102-71-6
	Trichloroacetic Acid	  	76-03-9
	Trifluoroacetic acid	  	76-05-1
	2,2,2-trifluoroethanol	  	75-89-8
	Triisopropylsilane	  	6485-79-6
	Tris	  	77-86-1
	Tris Hydrochloride	  	1183-53-1
	Tris propane	  	38571-73-2
	Triton-X-100	  	9002-93-1
	Trypan blue stain (0.4%)	  	72-57-1
	Tryptone peptone	  	N/A
	Tween 20	  	9005-65-5
	L-tyrosine, non animal source	  	T8566
	Urea	  	57-13-6
	N-vinyl-2-pyrrolidinone	  	88-12-0
	X-gal	  	7240-90-6
	Xylenes	  	mixture, 108-38-3, 95-47-6, 106-42-3, 100-41-4
	Xylene cyanol	  	2650-17-1
	Yeast extract	  	8013-01-2
	Zinc Acetate	  	557-34-6
	Zinc Citrate	  	5590-32-9
	Zinc Chloride	  	7646-85-7
	Zinc Gluconate	  	4468-02-4
	Zinc Nitrate	  	7779-88-6
	Zinc Sulfate, heptahydrate	  	7446-20-0

  
 G-7

 EXHIBIT H 
 TENANT’S PERSONAL PROPERTY 
  

					
	Manufacturing equipment,	  		  	Office furniture and equipment,
	including	  	Lab equipment, including	  	including
	Autoclaves	  	Autoclaves	  	Cubicles
	Biological Safety Cabinets	  	Balances	  	Closed office furniture
	Bioreactors	  	Biological Safety Cabinets	  	 Conference room furniture

Breakroom furniture and

	Carts and cage racks	  	Centrifuges	  	equipment
	Chromotography skids	  	Chemical Imagers	  	Lobby furniture
	Depyrogenation ovens	  	Conductivity meters	  	Patio furniture
	Dry Boxes	  	Corrosive storage cabinets	  	Chairs
	Equipment washers	  	Dry ice chests	  	PC workstations
	Fermentors	  	Electrophoresis	  	Fork lifts
	Fillers	  	Electroporation apparatus	  	Servers
	Filter integrity testers	  	 ELISA apparatus
 Fast Protein
Liquid
	  	
	Fume hoods	  	Chromatography	  	
	Gown room furniture	  	Film developers	  	
	Inspection stations	  	Flammable Storage cabinets	  	
	Isolators	  	 Flow cytometer, cell sorters

Fluorescence activated cell
	  	
	Light boxes	  	 sorting, cell sorters
 Fourier
transform infrared
	  	
	Lockers	  	spectroscopy	  	
	Lyophilizers	  	Freezers	  	
	Packaging stations	  	Fume hoods	  	
	Pallet racks	  	Gas chromatographs	  	
	Pumps	  	Gel stations	  	
	Scales	  	 Heat blocks
 High pressure
liquid
	  	
	Shakers	  	chromatography	  	
	Shelving, Wire Shelving,	  	Hood, capture hood, Flow Science	  	
	Metro Rack	  	hood, PCR set up hood	  	
	Sonicator, Ultrasonic Cleaner	  	Hot plates	  	
	Tangential flow filtration skids	  	Ice machines	  	
	 Tanks
 Temperature control
module
	  	Incubators	  	
	(Process Chillers)	  	Lab coat racks	  	
	Vacuum Pump	  	Laminar Flow Hoods	  	
	Vial Cappers	  	Mass Spectrophotometer	  	
	Vial Tray Loaders	  	Microfuges	  	
	Vial washers	  	Microscopes	  	
	Washers	  	 Microwaves
 Ovens

Ph meters
 Refrigerators

Rotovaps
	  	
		  	Spectrophotometer, UV Vis	  	
		  	Speed vacs	  	
		  	Stir plates	  	
		  	Synthesizers	  	
		  	Tables and lab chairs	  	
		  	Thermocyclers	  	
		  	Waterbaths	  	
		  	Waterpolishers	  	
		  	Washers	  	

  
 H-1

 EXHIBIT I 
 FORM OF TENANT ESTOPPEL CERTIFICATE 
  

	To:	BMR-Gateway Boulevard LLC 

 17190
Bernardo Center Drive 
 San Diego, California 92128 
 Attention: General Counsel/Real Estate 
 BioMed Realty, L.P. 

c/o BioMed Realty Trust, Inc. 
 17190 Bernardo Center Drive 
 San Diego, California 92128 

 

	 	Re:	Building No. 2 (the “Premises”) at 7555 Gateway Boulevard, Newark, California (the “Property”) 

The undersigned tenant (“Tenant”) hereby certifies to you as follows: 

1. Tenant is a tenant at the Property under a lease (the “Lease”) for the Premises dated as of March 31, 2008. The
Lease has not been cancelled, modified, assigned, extended or amended [except as follows: [            ]], and there are no other agreements, written or oral, affecting or relating to
Tenant’s lease of the Premises or any other space at the Property. The lease term expires on [            ], 20[    ]. 

2. Tenant took possession of the Premises, currently consisting of
[            ] square feet, on [            ], 20[    ], and commenced to pay rent on
[            ], 20[    ]. Tenant has full possession of the Premises, has not assigned the Lease or sublet any part of the Premises, and does not hold the Premises under
an assignment or sublease [, except as follows: [            ]]. 

3. All base rent, rent escalations and additional rent under the Lease have been paid through
[            ], 20[    ]. There is no prepaid rent [, except $[            ]][, and the amount of security
deposit is $[            ] [in cash][in the form of a letter of credit]]. Tenant currently has no right to any future rent abatement under the Lease. 

4. Base rent is currently payable in the amount of $[        ] per month. 

5. Tenant is currently paying estimated payments of additional rent of
$[            ] per month on account of real estate taxes, insurance, management fees and common area maintenance expenses. 

6. All work to be performed for Tenant under the Lease has been performed as required under the Lease and has been accepted by Tenant [,
except [            ]], and all allowances to be paid to Tenant, including allowances for tenant improvements, moving expenses or other items, have been paid. 

7. The Lease is in full force and effect, to Tenant’s knowledge free from default, and free from any event that could become a
default under the Lease, and Tenant has no claims against the landlord or offsets or defenses against rent, and there are no disputes with the landlord [, except
[                ]]. Tenant has received no notice of prior sale, transfer, assignment, hypothecation or pledge of the Lease or of the rents payable thereunder [, except
[            ]]. 
 8. [Tenant has the following expansion rights or
options for the Property: [            ].][Tenant has no rights or options to purchase the Property.] 
 9. To Tenant’s knowledge, no hazardous wastes have been generated, treated, stored or disposed of by or on behalf of Tenant in, on or around the Premises or the Project in violation of any
environmental laws. 
 10. The undersigned has executed this Estoppel Certificate with the knowledge and understanding that
[INSERT NAME OF LANDLORD, PURCHASER OR LENDER, AS APPROPRIATE] or its assignee is acquiring the Property in reliance on this certificate and that the undersigned shall be bound by this certificate. The statements contained herein may be relied

  
 I-1

 
upon by [INSERT NAME OF PURCHASER OR LENDER, AS APPROPRIATE], [LANDLORD], BioMed Realty, L.P., BioMed Realty Trust, Inc., and any mortgagee of the Property and their respective successors and
assigns. 
 Any capitalized terms not defined herein shall have the respective meanings given in the Lease. 

Dated this [    ] day of [            ], 20[    ].

 [            ], 
 a [            ] 
  

			
	By:	 	  

	Name:	 	  

	Title:	 	  

  
 I-2

 EXHIBIT J 
 FORM OF LANDLORD ESTOPPEL CERTIFICATE 
 To:
[            ] 
  

	 	Re:	Building No. 2 (the “Premises”) at 7555 Gateway Boulevard, Newark, California (the “Property”) 

The undersigned tenant (“Landlord”) hereby certifies to you as follows: 

1. Landlord is landlord under a lease for the Premises dated as of March 31, 2008 (the “Lease”). The Lease has not
been cancelled, modified, assigned, extended or amended [except as follows: [            ]], and there are no other agreements, written or oral, affecting or relating to the lease by
                    . (“Tenant”), of the Premises or any other space at the Property. The lease term expires on
[            ], 20[    ]. 
 2. Tenant took
possession of the Premises, currently consisting of [            ] square feet, on [            ], 20[    ],
and commenced to pay rent on [            ], 20[    ]. 
 3. All base rent, rent escalations and additional rent under the Lease have been paid through [            ], 20[    ].
There is no prepaid rent [, except $[            ]][, and the amount of security deposit is $[            ] [in cash][in the form
of a letter of credit]]. Tenant currently has no right to any future rent abatement under the Lease. 
 4. Base rent is
currently payable in the amount of $[            ] per month. 
 5.
Tenant is currently paying estimated payments of additional rent of $[            ] per month on account of real estate taxes, insurance, management fees and common area maintenance
expenses. 
 6. The Lease is in full force and effect, to the best of Landlord’s knowledge free from default, and free from
any event that could become a default under the Lease; and there are no disputes with Tenant [, except [            ]]. 

7. [Tenant has the following expansion rights or options for the Property:
[            ].][Tenant has no rights or options to purchase the Property.] 
 8. The undersigned has executed this Estoppel Certificate with the knowledge and understanding that [INSERT NAME OF PURCHASER OR LENDER, AS APPROPRIATE] is relying on this certificate and that the
undersigned shall be bound by this certificate. The statements contained herein may be relied upon by [INSERT NAME OF PURCHASER OR LENDER, AS APPROPRIATE] and its respective successors and assigns. 

Any capitalized terms not defined herein shall have the respective meanings given in the Lease. 
 Dated this [    ] day of [            ], 20[    ]. 

[            ], 
 a [            ] 
  

			
	By:	 	  

	Name:	 	  

	Title:	 	  

  
 J-1

 EXHIBIT K 
 RESERVED PARKING 
 

 

  
 K-1

 EXHIBIT L 
 LOCATION OF EXTERIOR ITEMS 
 

 

  
 L-1

 EXHIBIT M 
 SUBORDINATE ROFR PREMISES 
 

 

  
 M-1

 EXHIBIT N 
 COMMISSIONING 
 Landlord shall prepare the commissioning documents (pre-functional
checklists and functional checklists) for the following systems: 
  

	 	•	 	 Purified water; 

  

	 	•	 	 WFI; 

  

	 	•	 	 Clean steam; 

  

	 	•	 	 CDA; 

  

	 	•	 	 Nitrogen; 

  

	 	•	 	 HVAC cGMP equipment and systems; 

  

	 	•	 	 Emergency power generation; 

  

	 	•	 	 Vacuum; and 

  

	 	•	 	 Process heating and cooling water. 

  
 N-1

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00225-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00225-of-00352.parquet"}]]