Document:

EX-4.2

 Exhibit 4.2 

INVUITY, INC. 
 FOURTH
AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT 
 February 6, 2015 

 TABLE OF CONTENTS 

 

							
	 	 	 	  	Page	 
	 1. General Provisions
	  	 	1	  
			
	 1.1
	 	Definitions	  	 	2	  
		
	 2. Restrictions on Transfer; Registration
	  	 	4	  
			
	 2.1
	 	Restrictions on Transfer	  	 	4	  
	 2.2
	 	Demand Registration	  	 	5	  
	 2.3
	 	Piggyback Registration Rights	  	 	7	  
	 2.4
	 	Form S-3 Registration Rights	  	 	7	  
	 2.5
	 	Obligations of the Company	  	 	9	  
	 2.6
	 	Obligation to Effect Registration	  	 	10	  
	 2.7
	 	Expenses of Registration	  	 	11	  
	 2.8
	 	Underwriting Requirements	  	 	11	  
	 2.9
	 	Delay of Registration	  	 	12	  
	 2.10
	 	Indemnification	  	 	12	  
	 2.11
	 	Reports Under Exchange Act	  	 	14	  
	 2.12
	 	Assignment of Registration Rights	  	 	15	  
	 2.13
	 	Amendment of Registration Rights	  	 	15	  
	 2.14
	 	Limitations on Subsequent Registration Rights	  	 	16	  
	 2.15
	 	“Market Stand-Off” Agreement	  	 	16	  
	 2.16
	 	Agreements to Furnish Information	  	 	17	  
	 2.17
	 	Termination of Registration Rights	  	 	17	  
		
	 3. Covenants of the Company
	  	 	17	  
			
	 3.1
	 	Financial Information	  	 	17	  
	 3.2
	 	Right of First Offer	  	 	18	  
	 3.3
	 	Confidentiality of Records	  	 	19	  
	 3.4
	 	Reservation of Common Stock	  	 	19	  
	 3.5
	 	Equity Awards	  	 	19	  
	 3.6
	 	Directors’ and Officers’ Insurance and Indemnification	  	 	20	  
	 3.7
	 	Inspection Rights	  	 	20	  
	 3.8
	 	Invention Assignment and Confidentiality Agreement	  	 	20	  
	 3.9
	 	Protective Provisions Requiring Board Consent	  	 	20	  
	 3.10
	 	Board Consent for Exceptions to Conversion Price Adjustments	  	 	21	  
	 3.11
	 	Approval for Acquisition or Dissolution	  	 	22	  
	 3.13
	 	Termination of Certain Covenants	  	 	22	  
		
	 4. Miscellaneous
	  	 	22	  
			
	 4.1
	 	Successors and Assigns	  	 	22	  
	 4.2
	 	Governing Law	  	 	22	  
	 4.3
	 	Counterparts; Facsimile Signatures	  	 	22	  
	 4.4
	 	Titles and Subtitles	  	 	22	  
	 4.5
	 	Notices	  	 	23	  
	 4.6
	 	Attorney’s Fees	  	 	23	  
	 4.7
	 	Amendments and Waivers	  	 	23	  

  
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	 4.8
		Effect of Amendment or Waiver		 	23	  
	 4.9
		Severability		 	23	  
	 4.10
		Aggregation of Stock		 	23	  
	 4.11
		Entire Agreement		 	24	  
	 4.12
		Delays or Omissions		 	24	  
	 4.13  
		Prior Agreement Superseded.		 	24	  

 Schedule A – Schedule of Investors 

Schedule B – Schedule of Key Holders 

  
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 FOURTH AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT 

THIS FOURTH AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT (this “Agreement”) is made as of February 6,
2015, by and among INVUITY, INC., a California corporation (the “Company”), the investors listed on Schedule A hereto, referred to hereafter as the “Investors” and each
individually as an “Investor” and the other shareholders of the Company listed on Schedule B hereto, referred to hereafter as the “Key Holders” and each individually as a “Key
Holder,” Lighthouse and SVB. 
 RECITALS 

WHEREAS: The Company, the Key Holders, and certain of the Investors (the “Prior Parties”) have previously
entered into a Third Amended and Restated Investor Rights Agreement, dated as of February 28, 2014 (the “Prior Rights Agreement”), pursuant to which the Company granted such Investors certain registration rights,
information rights and other rights. 
 WHEREAS: The undersigned Prior Parties desire to amend and restate in its entirety the Prior
Rights Agreement and to accept the rights created pursuant hereto in lieu of the rights granted to them under the Prior Rights Agreement. 

WHEREAS: Certain of the Investors are parties to the Series F Preferred Stock Purchase Agreement dated as of the date hereof
between the Company and such Investors (the “Purchase Agreement”), such Investors’ obligations under which are conditioned upon the execution and delivery of this Agreement by such Investors, the Company, and the
“Requisite Percentage” (as defined in the Prior Rights Agreement), which shall constitute written consent for waiver pursuant to Sections 2.13 and 2.14, as well as amendment of the Prior Rights Agreement in its entirety
pursuant to Section 4.7 of the Prior Rights Agreement pursuant to the Purchase Agreement. 
 NOW, THEREFORE, in consideration of
these premises and for other good and valid consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto agree as follows: 
  

	 	1.	General Provisions 

  

	 	A.	Amendments of Prior Rights Agreement; Waiver of Right of First Offer. 

 Effective
and contingent (i) upon execution of this Agreement by the Company and the Requisite Percentage (as defined in the Prior Rights Agreement), and (ii) upon the “Closing” under the Purchase Agreement, (A) the Prior Rights
Agreement is hereby amended and restated in its entirety to read as set forth in this Agreement, and (B) the Company, the Key Holders, and the Investors hereby agree to be bound by the provisions hereof as the sole agreement of the Company, the
Key Holders and the Investors with respect to registration rights of the Company’s securities and certain other rights, as set forth herein. The Investors that are Major Investors (as defined in the Prior Rights Agreement) hereby waive the
Right of First Offer, including the notice requirements, set forth in Section 3.2 of the Prior Rights Agreement with respect to the issuance of Series F Preferred Stock. 

	 	1.1	Definitions 

 For purposes of this Agreement: 

(a) “Common Stock” means the Common Stock of the Company. 

(b) “Exchange Act” shall mean the Securities Exchange Act of 1934, as amended, or any similar successor federal
statute and the rules and regulations thereunder, all as the same shall be in effect from time to time. 
 (c) “Form S-3” means such form under the Securities Act as in effect on the date hereof or any registration form under the Securities Act subsequently adopted by the SEC in lieu of Form S-3 that permits inclusion
or incorporation of substantial information by reference to other documents filed by the Company with the SEC. 
 (d)
“Holder” means any person owning or having the right to acquire Registrable Securities or any assignee of record thereof in accordance with Section 2.12 hereof and shall include, without limitation, Lighthouse.

 (e) “Initial Offering” means the closing of the Company’s first firm commitment underwritten public offering
of its Common Stock registered under the Securities Act. 
 (f) “Initiating Holders” shall have the meaning given to
such term in Section 2.2(b) hereof. 
 (g) “Lighthouse” means Lighthouse Capital Partners VI, L.P. 

(h) “Register,” “registered,” and “registration” refer to a
registration effected by preparing and filing a registration statement or similar document in compliance with the Securities Act, and the declaration or ordering of effectiveness of such registration statement or document. 

(i) “Registrable Securities” means (i) the Common Stock issuable or issued upon conversion of the Shares,
(ii) shares of Common Stock issued to those individuals and in the amounts set forth on Schedule B attached hereto (the “Key Holder Shares”); provided, however, that such shares of Common Stock shall
not be deemed to be Registrable Securities and the aforementioned individuals shall not be deemed Holders for the purposes of Sections 2.2 and 2.4 (as applicable), (iii) all shares of Common Stock of the Company now or hereafter
held by Lighthouse, including, without limitation, the shares of Common Stock issued or issuable upon conversion of the shares of Series B Preferred Stock or any other convertible securities now or hereafter held by Lighthouse (including without
limitation the Series B Preferred Stock or other securities issued or issuable upon exercise of warrants to purchase Series B Preferred Stock or such other securities now or hereafter held by Lighthouse) or any shares of Common Stock otherwise
issuable under warrants held by Lighthouse, and (iv) any 

  
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Common Stock of the Company issued as (or issuable upon the conversion or exercise of any warrant, right or other security that is issued as) a dividend or other distribution with respect to, or
in exchange for or in replacement of the shares referenced in (i), (ii) and (iii) above, excluding in all cases, however, any Registrable Securities sold by a Holder in a transaction in which such Holder’s rights under
Section 2 are not assigned. Notwithstanding the foregoing, Registrable Securities shall not include any securities (i) sold by a person to the public either pursuant to a registration statement or Rule 144, (ii) sold in a
private transaction in which the transferor’s rights under Section 2 of this Agreement are not assigned or (iii) held by a Holder (together with its affiliates) if, as reflected on the Company’s list of shareholders, such
Holder (together with its affiliates) holds less than 1% of the Company’s outstanding Common Stock (treating all shares of Preferred Stock on an as converted basis), the Company has completed its Initial Offering and all shares of Common Stock
of the Company issuable or issued upon conversion of the Shares held by and issuable to such Holder (and its affiliates) may be sold pursuant to Rule 144 during any ninety (90) day period. 

(j) The number of shares of “Registrable Securities then outstanding” shall be determined by the number of shares of
Common Stock outstanding which are, and the number of shares of Common Stock issuable pursuant to then exercisable or convertible securities which are exercisable or convertible into, Registrable Securities. 

(k) “Registration Expenses” shall mean all expenses, other than Selling Expenses, incurred by the Company in complying
with Sections 2.2, 2.3 and 2.4 hereof, including, without limitation, all registration and filing fees, printing expenses, fees and disbursements of counsel and accountants for the Company, reasonable fees and disbursements not
to exceed fifty thousand dollars ($50,000) for one special counsel for the Holders, blue sky fees and expenses and the expense of any special audits incident to or required by any such registration (but excluding the compensation of regular
employees of the Company which shall be paid in any event by the Company). 
 (l) “Rule 144” shall mean Rule 144 of
the Securities Act. 
 (m) “SEC” shall mean the Securities and Exchange Commission or any other federal agency at
the time administering the Securities Act. 
 (n) “Securities Act” means the Securities Act of 1933, as amended, or
any similar successor federal statute and the rules and regulations thereunder, all as the same shall be in effect from time to time. 
 (o)
“Selling Expenses” shall mean all underwriting discounts and selling commissions applicable to the sale of securities. 

(p) “Shares” shall mean the Company’s Series A Preferred Stock, Series B Preferred Stock, Series C Preferred
Stock, Series D Preferred Stock, Series E Preferred Stock and Series F Preferred Stock held by the Investors listed on Schedule A hereto and their permitted assigns and the Series B Preferred Stock, Series C Preferred Stock and
Series E Preferred Stock issuable upon exercise of the Warrants. 

  
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 (q) “Special Registration Statement” shall mean (i) a registration
statement relating to any employee benefit plan, (ii) any registration statements with respect to any corporate reorganization or transaction as defined under Rule 145 of the Securities Act and any registration statements related to the
issuance or resale of securities issued in such a transaction, (iii) a registration related to stock issued upon conversion of debt securities, or (iv) any registration on any form which does not include substantially the same information
as would be required to be included in a registration statement covering the sale of the Registrable Securities. 
 (r)
“SVB” shall mean Silicon Valley Bank and its affiliates, which shall be deemed to be a Holder, except with respect to Sections 2.2, 2.14, 3 and 4.7 of this Agreement. 

(s) “Warrants” shall mean those certain warrants to purchase Series B Preferred Stock, Series C Preferred Stock and
Series E Preferred Stock, issued and outstanding as of the date of this Agreement. 
 (t) “Wellington Investor”
shall mean each of the following entities: Hadley Harbor Master Investors (Cayman) L.P. and The Hartford Capital Appreciation Fund. 
  

	 	2.	Restrictions on Transfer; Registration 

  

	 	2.1	Restrictions on Transfer 

 (a) Each Holder agrees not to make any disposition of all or
any portion of the Shares or Registrable Securities unless and until: 
 (i) there is then in effect a registration
statement under the Securities Act covering such proposed disposition and such disposition is made in accordance with such registration statement; 

(ii) such disposition is completed in compliance with Rule 144; or 

(iii) (A) The transferee has agreed in writing to be bound by the terms of this Agreement, (B) such Holder shall have
notified the Company of the proposed disposition and (C) if reasonably requested by the Company, such Holder shall have furnished the Company with an opinion of counsel, reasonably satisfactory to the Company, that such disposition will not
require registration of such shares under the Securities Act. 
 It is agreed that the Company will not require opinions of counsel for transactions made
pursuant to Rule 144 except in unusual circumstances. After its Initial Offering, the Company will not require the transferee to be bound by the terms of this Agreement, but in such case, the transferee shall not be entitled to the benefits of
this Agreement. 

  
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 (b) Notwithstanding the provisions of Section 2.1(a) above, no such restriction
shall apply to a transfer that does not involve a change in beneficial ownership, or to a transfer by a Holder that is (A) a partnership transferring to its partners, limited partners, former partners, former limited partners, or to estates of
any of its partners or limited partners in accordance with partnership interests, (B) a corporation transferring to a subsidiary, parent, or other affiliate, (C) a limited liability company transferring to its members, former members or to
the estates of any of its members, in accordance with their interest in the limited liability company, or (D) an individual transferring to the Holder’s family member or trust for the benefit of an individual Holder; provided that
in each case the transferee will agree in writing to be subject to the terms of this Agreement to the same extent as if such transferee were an original Holder hereunder. 

(c) Each certificate representing Shares or Registrable Securities shall be stamped or otherwise imprinted with legends substantially similar
to the following (in addition to any legend required under applicable state securities laws): 
 “THE SALE, PLEDGE, HYPOTHECATION OR
TRANSFER OF THE SECURITIES REPRESENTED BY THIS CERTIFICATE IS SUBJECT TO THE TERMS AND CONDITIONS OF A CERTAIN INVESTOR RIGHTS AGREEMENT BY AND BETWEEN THE SHAREHOLDER AND THE COMPANY. COPIES OF SUCH AGREEMENT MAY BE OBTAINED UPON WRITTEN REQUEST TO
THE SECRETARY OF THE COMPANY.” 
 (d) The Company shall be obligated to reissue promptly unlegended certificates at the request of any
Holder thereof if the Company has completed its Initial Offering and the Holder shall have obtained an opinion of counsel (which counsel may be counsel to the Company) reasonably acceptable to the Company to the effect that the securities proposed
to be disposed of may lawfully be so disposed of without registration, qualification and legend. 
 (e) Any legend endorsed on an instrument
pursuant to applicable state securities laws and the stop-transfer instructions with respect to such securities shall be removed upon receipt by the Company of an order of the appropriate blue sky authority authorizing such removal. 

 

	 	2.2	Demand Registration 

 (a) Subject to the conditions of this Section 2.2, if
the Company shall receive at any time after the earlier of (i) five (5) years from the Closing (as defined in the Purchase Agreement) and (ii) six (6) months after the effective date of the registration statement for the Initial
Offering (other than a Special Registration Statement), a written request from the Holders of at least forty percent (40%) of the Registrable Securities then outstanding that the Company file a registration statement under the Securities Act
covering the registration of Registrable Securities having an anticipated aggregate offering price in excess of $5,000,000, then the Company shall: 

(i) within twenty (20) days of the receipt thereof, give written notice of such registration request to all Holders; and

  
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 (ii) file as soon as practicable a registration statement under the Securities
Act covering all Registrable Securities that the Holders request to be registered, subject to the limitations of Section 2.2(b). 

(b) If the Holders initiating the registration request hereunder (“Initiating Holders”) intend to distribute the
Registrable Securities covered by their request by means of an underwriting, they shall so advise the Company as a part of their request made pursuant to Section 2.2(a) and the Company shall include such information in the written notice
referred to in Section 2.2(a)(i). The underwriter or underwriters shall be selected by the Initiating Holders with the consent of the Company (not to be unreasonably withheld). In such event, the right of any Holder to include such
Holder’s Registrable Securities in such registration shall be conditioned upon such Holder’s participation in such underwriting and the inclusion of such Holder’s Registrable Securities in the underwriting to the extent provided
herein. All Holders proposing to distribute their securities through such underwriting shall together with the Company, enter into an underwriting agreement in customary form with the underwriter or underwriters selected for such underwriting.
Notwithstanding any other provision of this Section 2.2, if the underwriter advises the Initiating Holders in writing that marketing factors require a limitation of the number of shares to be underwritten, then the Initiating Holders
shall so advise all Holders of Registrable Securities that would otherwise be underwritten pursuant hereto, and the number of shares of Registrable Securities that may be included in the underwriting shall be allocated among, all Holders thereof,
including the Initiating Holders, in proportion (as nearly as practicable) to the amount of Registrable Securities owned by each Holder or in such other proportions as shall be mutually agreed to by a majority in interest of such Initiating Holders;
provided, however, that the number of shares of Registrable Securities to be included in such underwriting shall not be reduced unless all other securities are first entirely excluded from the underwriting. Any Registrable Securities excluded
or withdrawn from such underwriting shall be withdrawn from the registration. 
 The registration statement filed pursuant to the request of
the Initiating Holders may, subject to the provisions of Section 2.8 and the provisions of this Section 2.2(b), include other securities of the Company with respect to which registration rights have been granted, and may
include securities of the Company being sold for the account of the Company. 
 (c) Notwithstanding the foregoing, if the Company shall
furnish to the Initiating Holders a certificate signed by the Chief Executive Officer or President of the Company stating that in the good faith judgment of the Board of Directors of the Company, it would be seriously detrimental to the Company and
its shareholders for such registration statement to be filed and it is therefore essential to defer the filing of such registration statement, the Company shall have the right to defer taking action with respect to such filing for a period of not
more than ninety (90) days after receipt of the request of the Initiating Holders, provided that such right shall be exercised by the Company not more than once in any twelve (12)-month period. 

(d) The Company shall not be obligated to effect, or to take any action to effect, any registration pursuant to this Section 2.2:

  
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 (i) after the Company has effected two (2) registrations pursuant to this
Section 2.2 (counting for these purposes only (x) registrations which have been declared or ordered effective and pursuant to which securities have been sold and (y) demand registrations under this Section 2.2 which
have been forfeited or withdrawn by the Holders in accordance with Section 2.7; 
 (ii) during the period starting
with the date sixty (60) days prior to the Company’s good faith estimate of the date of filing of, and ending on a date one hundred eighty (180) days after the effective date of, a registration subject to Section 2.3
hereof; provided that the Company is actively employing in good faith all reasonable efforts to cause such registration statement to become effective; 

(iii) if within thirty (30) days of receipt of a written request from Initiating Holders pursuant to
Section 2.2(a), the Company gives notice to the Holders of the Company’s intention to file a registration statement for a public offering, other than pursuant to a Special Registration Statement within ninety (90) days; 

(iv) if the Initiating Holders propose to dispose of shares of Registrable Securities that may be immediately registered on
Form S-3 pursuant to a request made pursuant to Section 2.4 below; or 

(v) in any particular jurisdiction in which the Company would be required to qualify to do business or to execute a general
consent to service of process in effecting such registration, qualification or compliance. 
 2.3 Piggyback Registration Rights. If
(but without any obligation to do so) the Company proposes to register (including for this purpose a registration effected by the Company for shareholders other than the Holders) any of its Common Stock under the Securities Act in connection with a
firm commitment underwritten public offering solely of such Common Stock and solely for cash (other than a Special Registration Statement), the Company shall, at such time, promptly give each Holder written notice of such registration. Upon the
written request of each Holder given within ten (10) days after provision of written notice by the Company in accordance with Section 4.5, the Company shall, subject to the provisions of Section 2.8, cause to be
registered under the Securities Act all of the Registrable Securities that each such Holder has requested to be registered. 
 2.4 Form S-3 Registration Rights. In case the Company shall receive a written request from the Holders that the Company effect a registration on Form S-3 with
respect to all or a part of the Registrable Securities owned by such Holders, the Company will: 
 (a) promptly give written notice of the
proposed registration, and any related qualifications or compliances to all other Holders; and 
 (b) as soon as practicable, effect such
registration and all such qualifications and compliances as may be so requested and as would permit or facilitate the sale and distribution of all or such portion of such Holder’s or Holders’ Registrable Securities as are specified in such
request, together with all or such portion of the Registrable Securities of any other Holder or Holders joining in such request as are specified in a written request given within ten (10) days after provision of written notice by the Company in
accordance with Section 4.5; provided, however, that the Company shall not be obligated to effect any such registration pursuant to this Section 2.4: 

  
 7 

 (i) if Form S-3 is not available
for such offering by the Holders; 
 (ii) if the Holders, together with the holders of any other securities of the Company
entitled to inclusion in such registration, propose to sell Registrable Securities and such other securities (if any) at an aggregate price to the public (before deduction of any Selling Expenses) of less than $1,000,000; 

(iii) if the Company shall furnish to the Holders requesting a registration statement a certificate signed by the Chief
Executive Officer or President of the Company stating that in the good faith judgment of the Board of Directors of the Company, it would be seriously detrimental to the Company and its shareholders for such
Form S-3 registration to be effected at such time, in which event the Company shall have the right to defer the filing of the Form S-3 registration statement
for a period of not more than ninety (90) days after receipt of the request of the Holder or Holders under this Section 2.4, provided that such right shall be exercised by the Company not more than once in any twelve (12)-month
period; 
 (iv) if the Company has, within the six (6) month period preceding the date of such request, already
effected one (1) registration for the Holders pursuant to this Section 2.4; 
 (v) during the period
starting with the date sixty (60) days prior to the Company’s good faith estimate of the date of filing of, and ending on a date one hundred eighty (180) days after the effective date of, a registration subject to
Section 2.3 hereof; provided that the Company is actively employing in good faith all reasonable efforts to cause such registration statement to become effective; 

(vi) if within thirty (30) days of receipt of a written request from Initiating Holders pursuant to
Section 2.4(a), the Company gives notice to the Holders of the Company’s intention to file a registration statement for a public offering, other than pursuant to a Special Registration Statement within ninety (90) days; or 

(vii) in any particular jurisdiction in which the Company would be required to qualify to do business or to execute a general
consent to service of process in effecting such registration, qualification or compliance. 
 (c) Subject to the foregoing, the Company
shall file a registration statement covering the Registrable Securities and other securities so requested to be registered as soon as practicable after receipt of the request of the Holders. Registrations effected pursuant to this
Section 2.4 shall not be counted as demands for registration or registrations effected pursuant to Section 2.2. 

  
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 2.5 Obligations of the Company. Whenever required under this Section 2 to
effect the registration of any Registrable Securities, the Company shall as expeditiously as reasonably possible: 
 (a) Prepare and file
with the SEC a registration statement with respect to such Registrable Securities and use all reasonable efforts to cause such registration statement to become effective, and, upon the request of the Holders of a majority of the Registrable
Securities registered thereunder, keep such registration statement effective for a period of up to one hundred twenty (120) days or until the distribution contemplated in the Registration Statement has been completed, if a shorter period (the
“Effectiveness Period”); provided, however, that (i) the Effectiveness Period shall be extended for a period of time equal to the period the Holder refrains from selling any securities included in such
registration at the request of an underwriter of Common Stock (or other securities) of the Company; and (ii) in the case of any registration of Registrable Securities on Form S-3 which are intended
to be offered on a continuous or delayed basis, the Effectiveness Period shall be extended, if necessary, to keep the registration statement effective until all such Registrable Securities are sold up to one hundred eighty (180) days, provided
that Rule 415, or any successor rule under the Securities Act, permits an offering on a continuous or delayed basis, and provided further that applicable rules under the Securities Act governing the obligation to file a post-effective amendment permit, in lieu of filing a post-effective amendment which (A) includes any prospectus required by Section 10(a)(3) of the Securities
Act or (B) reflects facts or events representing a material or fundamental change in the information set forth in the registration statement, the incorporation by reference of information required to be included in (A) and (B) above
to be contained in periodic reports filed pursuant to Section 13 or 15(d) of the Exchange Act in the registration statement. In the event that, in the judgment of the Company, it is advisable to suspend use of the prospectus relating to such
registration statement for a discrete period of time (a “Deferral Period”) due to pending material corporate developments or similar material events that have not yet been publicly disclosed and as to which the Company
believes public disclosure will be prejudicial to the interests of the Company, the Company shall deliver a duly adopted and effective resolution of the Board of Directors of the Company, certified by a duly authorized officer of the Company, to
each Holder of Registrable Securities covered by such registration statement, to the effect of the foregoing and, upon receipt of such certificate, such Holders agree not to dispose of such Holders’ Registrable Securities covered by such
registration or prospectus (other than in transactions exempt from the registration requirements under the Securities Act); provided, however, that such Deferral Period shall be no longer than sixty (60) days. The Effectiveness Period
shall be extended for a period of time equal to such Deferral Period. In the event that a Holder receives a notice from the Company informing the Holder of the existence of a Deferral Period, such Holder shall be required to keep such existence
confidential. 
 (b) Prepare and file with the SEC such amendments and supplements to such registration statement and the prospectus used in
connection with such registration statement as may be necessary to comply with the provisions of the Securities Act with respect to the disposition of all securities covered by such registration statement. 

(c) Furnish to the Holders of Registrable Securities covered by such registration statement such numbers of copies of a prospectus, including
a preliminary prospectus, and any amendment or supplement thereto, all in conformity with the requirements of the Securities Act, and such other documents as they may reasonably request in order to facilitate the disposition of such Registrable
Securities. 

  
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 (d) Use all reasonable efforts to register and qualify the securities covered by such
registration statement under such other securities or Blue Sky laws of such jurisdictions as shall be reasonably requested by the Holders; provided that the Company shall not be required in connection therewith or as a condition thereto to qualify
to do business or to file a general consent to service of process in any such states or jurisdictions. 
 (e) In the event of any
underwritten public offering, enter into and perform its obligations under an underwriting agreement, in usual and customary form, with the managing underwriter of such offering. Each Holder participating in such underwriting shall also enter into
and perform such Holder’s obligations under such an agreement. 
 (f) Notify each Holder of Registrable Securities covered by such
registration statement at any time when a prospectus relating thereto is required to be delivered under the Securities Act of the happening of any event as a result of which the prospectus included in such registration statement, as then in effect,
includes an untrue statement of a material fact or omits to state a material fact required to be stated therein or necessary to make the statements therein, in the light of the circumstances under which they were made, not misleading. In the event
that a Holder receives such a notice from the Company, the Holder agrees to keep such suspension confidential. 
 (g) Cause all such
Registrable Securities registered pursuant hereunder to be listed on each securities exchange or automated quotation system on which similar securities issued by the Company are then listed. 

(h) Provide a transfer agent and registrar for all Registrable Securities registered pursuant hereunder and a CUSIP number for all such
Registrable Securities, in each case not later than the effective date of such registration. 
 (i) Use reasonable efforts to furnish, on
the date that such Registrable Securities are delivered to the underwriters for sale, if such securities are being sold through underwriters, (i) an opinion, dated as of such date, of the counsel representing the Company for the purposes of
such registration, in form and substance as is customarily given to underwriters in an underwritten public offering, addressed to the underwriters, if any, and (ii) a “comfort” letter dated as of such date, from the independent
certified public accountants of the Company, in form and substance as is customarily given by independent certified public accountants to underwriters in an underwritten public offering addressed to the underwriters. 

2.6 Obligation to Effect Registration. The Company shall have no obligation to effect a registration with respect to any registration
requested pursuant to Section 2.2 or Section 2.4 if the number of shares or the anticipated aggregate offering price of the Registrable Securities to be included in the registration does not equal or exceed the number of
shares or the anticipated aggregate offering price required to originally trigger the Company’s obligation to initiate such registration as specified in Section 2.2 or Section 2.4, whichever is applicable. 

  
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 2.7 Expenses of Registration 

(a) Except as specifically provided herein, all Registration Expenses incurred in connection with any registration pursuant to
Section 2.2, 2.3 or 2.4 herein shall be borne by the Company. All Selling Expenses incurred in connection with any registrations hereunder shall be borne by the Holders of the securities so registered pro rata on the basis
of the number of shares so registered. 
 (b) Notwithstanding Section 2.7(a), the Company shall not be required to pay for any
expenses of any registration proceeding begun pursuant to Section 2.2 or Section 2.4 if the registration request is subsequently withdrawn at the request of the Holders of a majority of the Registrable Securities to be
registered (in which case all participating Holders shall bear such expenses), unless the Holders of a majority of the Registrable Securities agree to forfeit their right to one demand registration pursuant to Section 2.2 or
Section 2.4, as applicable; provided, however, that if at the time of such withdrawal, the Holders have learned of a material adverse change in the condition or business of the Company from that known to the Holders at the time of
their request and have withdrawn the request with reasonable promptness following disclosure by the Company of such material adverse change, then the Holders shall not be required to pay any of such expenses and shall not be required to forfeit a
demand registration pursuant to Section 2.2 or Section 2.4, as applicable. 
 2.8 Underwriting Requirements.
In connection with any offering involving an underwriting of shares being issued by the Company, the Company shall not be required under Section 2.3 to include any of the Holders’ securities in such underwriting unless they accept
the terms of the underwriting as agreed upon between the Company and the underwriters selected by it, and then only in such quantity as the underwriters determine in their sole discretion will not jeopardize the success of the offering by the
Company. If the total amount of securities, including Registrable Securities, requested by shareholders to be included in such offering exceeds the amount of securities sold other than by the Company that the underwriters determine in their sole
discretion is compatible with the success of the offering, then the Company shall be required to include in the offering only that number of such securities, including Registrable Securities, which the underwriters determine in their sole discretion
will not jeopardize the success of the offering (the securities so included to be apportioned pro rata among the selling shareholders according to the total amount of securities entitled to be included therein owned by each selling shareholder or in
such other proportions as shall mutually be agreed to by such selling shareholders); provided, however, that in no event shall the amount of securities of the selling Holders included in the offering be reduced below twenty-five percent
(25%) of the total amount of securities included in such offering, unless such offering is the Initial Offering, in which case the selling shareholders may be excluded if the underwriters make the determination described above. In no event
shall shares of Registrable Securities held by the Investors be excluded from such registration unless any other shares held by selling shareholders, including all Key Holder Shares have been completely excluded from such registration. For purposes
of apportionment, for any selling shareholder that is a Holder of Registrable Securities and that is a partnership, limited liability company or corporation, the partners, retired partners, members, former members and shareholders of such Holder, or
the estates and family members of any such partners and retired partners, members or former members and any trusts for the benefit of any of the foregoing persons and affiliates of such Holder shall be deemed to be a

  
 11 

 
single “selling shareholder,” and any pro rata reduction with respect to such “selling shareholder” shall be based upon the aggregate amount of Registrable Securities owned by
all entities and individuals included in such “selling shareholder,” as defined in this sentence. 
 2.9 Delay of
Registration. No Holder shall have any right to obtain or seek an injunction restraining or otherwise delaying any such registration as the result of any controversy that might arise with respect to the interpretation or implementation of this
Section 2. 
 2.10 Indemnification. In the event any Registrable Securities are included in a registration statement under
this Section 2: 
 (a) To the extent permitted by law, the Company will indemnify and hold harmless each Holder of such
Registrable Securities, the officers, directors, partners, members, controlling person of each such Holder, any underwriter (as defined in the Securities Act) for such Holder and each person, if any, who controls such Holder or underwriter within
the meaning of the Securities Act or the Exchange Act, against any losses, claims, damages, or liabilities (joint or several) to which they may become subject under the Securities Act, the Exchange Act or other federal or state securities laws,
insofar as such losses, claims, damages, or liabilities (or actions in respect thereof) arise out of or are based upon any of the following statements, omissions or violations (collectively, a “Violation”): (i) any
untrue statement or alleged untrue statement of a material fact contained in such registration statement, including any preliminary prospectus, free writing prospectus or final prospectus contained therein or any amendments or supplements thereto,
(ii) the omission or alleged omission to state therein a material fact required to be stated therein, or necessary to make the statements therein not misleading, or (iii) any violation or alleged violation by the Company of the Securities
Act, the Exchange Act, any state securities law or any rule or regulation promulgated under the Securities Act, the Exchange Act or any state securities law; and the Company will reimburse, as incurred, each such Holder, officer, director, partner,
member, underwriter or controlling person, for any legal or other expenses reasonably incurred by them in connection with investigating or defending any such loss, claim, damage, liability, or action; provided, however, that notwithstanding
anything to the contrary contained herein, the indemnification contained in this Section 2.10(a): (i) shall not apply to a claim by a Holder, officer, director, partner, member, underwriter or controlling person arising out of or
based upon a Violation which occurs in reliance upon and in conformity with information furnished in writing to the Company by such person for such person expressly for inclusion in the registration statement or any such amendment thereof or
supplement thereto, if such prospectus was timely made available by the Company pursuant to the terms of this Agreement; (ii) with respect to any preliminary prospectus, shall not inure to the benefit of any such person from whom the person
asserting any such claim purchased the Registrable Securities that are the subject thereof (or to the benefit of any person controlling such person) if the untrue statement or omission of material fact contained in the preliminary prospectus was
corrected in the prospectus, as then amended or supplemented, if such prospectus was timely made available by the Company pursuant to the terms hereof, and such Holder, officer, director, partner, member, underwriter or controlling person was
promptly advised in writing not to use the incorrect prospectus prior to the use giving rise to a violation and such person, notwithstanding such advice, used it or failed to deliver the correct prospectus as required by the Securities Act and such
correct prospectus was timely made available pursuant 

  
 12 

 
to the terms hereof; (iii) shall not be available to the extent such claim is based on a failure of such person to deliver or to cause to be delivered the prospectus made available by the
Company, including a corrected prospectus, if such prospectus or corrected prospectus was timely made available by the Company pursuant to the terms of this Agreement; and (iv) shall not apply to amounts paid in settlement of any claim if such
settlement is effected without the prior written consent of the Company, which consent shall not be unreasonably withheld. 
 (b) To the
extent permitted by law, each selling Holder will indemnify and hold harmless the Company, each of its directors, each of its officers who has signed the registration statement, each person, if any, who controls the Company within the meaning of the
Securities Act, any underwriter, any other Holder selling securities in such registration statement and any officer, director or controlling person of any such underwriter or other Holder, against any losses, claims, damages, or liabilities (joint
or several) to which any of the foregoing persons may become subject, under the Securities Act, the Exchange Act or other federal or state securities laws insofar as such losses, claims, damages, or liabilities (or actions in respect thereto) arise
out of or are based upon any Violation, in each case to the extent (and only to the extent) that such Violation occurs in reliance upon and in conformity with written information furnished by such Holder expressly for use in connection with such
registration; and each such Holder will reimburse, as incurred any legal or other expenses reasonably incurred by any person intended to be indemnified pursuant to this Section 2.10(b), in connection with investigating or defending any
such loss, claim, damage, liability, or action; provided, however, that the indemnity agreement contained in this Section 2.10(b) shall not apply to amounts paid in settlement of any such loss, claim, damage, liability or action
if such settlement is effected without the consent of the Holder, which consent shall not be unreasonably withheld; provided further, that, in no event shall any Holder’s cumulative aggregate liability under this
Section 2.10(b) or under Section 2.10(c) or 2.10(d), or under such Sections collectively, exceed the aggregate gross proceeds (net of Selling Expenses) from the sale of the Registrable Securities received by such
Holder from the shares sold by such Holder in the offering in question. 
 (c) Promptly after receipt by an indemnified party under this
Section 2.10 of notice of the commencement of any action (including any governmental action), such indemnified party will, if a claim in respect thereof is to be made against any indemnifying party under this Section 2.10,
deliver to the indemnifying party a written notice of the commencement thereof and the indemnifying party shall have the right to participate in, and, to the extent the indemnifying party so desires, jointly with any other indemnifying party
similarly noticed, to assume the defense thereof with counsel mutually satisfactory to the parties; provided, however, that an indemnified party (together with all other indemnified parties that may be represented without conflict by one
counsel) shall have the right to retain one separate counsel, with the fees and expenses to be paid by the indemnifying party, if representation of such indemnified party by the counsel retained by the indemnifying party would be inappropriate due
to actual or potential differing interests between such indemnified party and any other party represented by such counsel in such proceeding. The failure to deliver written notice to the indemnifying party within a reasonable time of the
commencement of any such action, if materially prejudicial to its ability to defend such action, shall relieve such indemnifying party of any liability to the indemnified party under this Section 2.10 to the extent of such prejudice, but
the omission so to deliver written notice to the indemnifying party will not relieve it of any liability that it may have to any indemnified party otherwise than under this Section 2.10. An

  
 13 

 
indemnifying party shall not, without the prior written consent of the indemnified parties, settle, compromise or consent to the entry of any judgment with respect to any pending or threatened
claim, action, suit or proceeding in respect of which indemnification may be sought hereunder by such indemnified parties (whether or not the indemnified parties are actual or potential parties to such claim or action) unless such settlement,
compromise or consent includes a release of such indemnified party reasonably acceptable to such indemnified party from all liability arising out of such claim, action, suit or proceeding or unless the indemnifying party shall confirm in a written
agreement reasonably acceptable to such indemnified party, that notwithstanding any federal, state or common law, such settlement, compromise or consent shall not adversely affect the right of any indemnified party to indemnification as provided in
this Section 2. 
 (d) If the indemnification provided for in this Section 2.10 is held by a court of competent
jurisdiction to be unavailable to an indemnified party with respect to any loss, liability, claim, damage, or expense referred to therein, then the indemnifying party, in lieu of indemnifying such indemnified party hereunder, shall contribute to the
amount paid or payable by such indemnified party as a result of such loss, liability, claim, damage, or expense in such proportion as is appropriate to reflect the relative fault of the indemnifying party on the one hand and of the indemnified party
on the other in connection with the statements or omissions that resulted in such loss, liability, claim, damage, or expense as well as any other relevant equitable considerations; provided, however, that no contribution by any Holder, when
combined with any amounts paid by such Holder pursuant to Sections 2.10(b) or 2.10(c) shall exceed the aggregate gross proceeds (net of Selling Expenses) from the offering received by such Holder. The relative fault of the indemnifying
party and of the indemnified party shall be determined by reference to, among other things, whether the untrue or alleged untrue statement of a material fact or the omission to state a material fact relates to information supplied by the
indemnifying party or by the indemnified party and the parties’ relative intent, knowledge, access to information, and opportunity to correct or prevent such statement or omission. 

(e) Notwithstanding the foregoing, to the extent that the provisions on indemnification and contribution contained in the underwriting
agreement entered into in connection with the underwritten public offering are in conflict with the foregoing provisions, the provisions in the underwriting agreement shall control. 

(f) The obligations of the Company and Holders under this Section 2.10 shall survive the completion of any offering of Registrable
Securities in a registration statement under this Section 2, and any termination of this Agreement. 
 2.11 Reports Under
Exchange Act. With a view to making available to the Holders the benefits of Rule 144 and any other rule or regulation of the SEC that may at any time permit a Holder to sell securities of the Company to the public without registration or
pursuant to a registration on Form S-3, the Company agrees to: 
 (a) make and keep public
information available, as those terms are understood and defined in Rule 144, at all times after ninety (90) days after the effective date of the first registration statement filed by the Company for the offering of its securities to the
general public; 

  
 14 

 (b) file with the SEC in a timely manner all reports and other documents required of the Company
under the Securities Act and the Exchange Act; and 
 (c) furnish to any Holder, so long as the Holder owns any Registrable Securities,
forthwith upon request (i) a written statement by the Company that it has complied with the reporting requirements of Rule 144 (at any time after ninety (90) days after the effective date of the first registration statement filed by
the Company), the Securities Act and the Exchange Act (at any time after it has become subject to such reporting requirements), or that it qualifies as a registrant whose securities may be resold pursuant to
Form S-3 (at any time after it so qualifies), (ii) a copy of the most recent annual or quarterly report of the Company and such other reports and documents so filed by the Company, if such reports or
documents are not available on EDGAR, and (iii) such other information as may be reasonably requested in availing any Holder of any rule or regulation of the SEC that permits the selling of any such securities without registration or pursuant
to such form. 
 2.12 Assignment of Registration Rights. The rights to cause the Company to register Registrable Securities pursuant
to this Section 2 may be assigned (but only with all related obligations) by (a) a Holder to a transferee or assignee of such securities who, after such assignment or transfer, holds at least 50,000 of the shares of Registrable
Securities (subject to appropriate adjustment for any stock splits, dividends, consolidations, combinations, subdivisions, reclassifications and the like effected after the date hereof (“Recapitalizations”) and other
recapitalizations and including for purposes of such calculation the shares of Common Stock then issuable upon conversion of Preferred Stock) or (b) a Holder to its shareholders, partners, members, former partners or former members (or their
estates), subsidiaries or affiliates; provided that: (i) the Company is, within a reasonable time after such transfer, furnished with written notice of the name and address of such transferee or assignee and the securities with respect to which
such registration rights are being assigned; (ii) such transferee or assignee agrees in writing to be bound by and subject to the terms and conditions of this Agreement; and (iii) such assignment shall be effective only if immediately
following such transfer the further disposition of such securities by the transferee or assignee is restricted under the Securities Act. For the purposes of determining the number of shares of Registrable Securities held by a transferee or assignee,
the holdings of transferees and assignees of a partnership or limited liability company who are partners or retired partners of such partnership or members of such limited liability company (including spouses and ancestors, lineal descendants and
siblings of such partners or members or spouses who acquire Registrable Securities by gift, will or intestate succession) shall be aggregated together and with the partnership or limited liability company, as the case may be; provided that all
assignees and transferees who would not qualify individually for assignment of registration rights shall have a single attorney-in-fact for the purpose of exercising any
rights, receiving notices or taking any action under this Section 2. 
 2.13 Amendment of Registration Rights. Any
provision of this Section 2 may be amended and the observance thereof may be waived (either generally or in a particular instance and either retroactively or prospectively), only with the written consent of the Company and the Holders of
at least sixty-five percent (65%) of the Registrable Securities then outstanding (excluding any Key Holder Shares in all cases other than amendments and/or waivers of Section 2.3) (the “Requisite
Percentage”). Any amendment or waiver effected in accordance with this Section 2.13 shall be binding upon each Holder and the Company. 

  
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 2.14 Limitations on Subsequent Registration Rights. From and after the date of this
Agreement, except as permitted by Section 4.7 hereof, the Company shall not, without the prior written consent of the Requisite Percentage, enter into any agreement with any holder or prospective holder of any securities of the Company
that would allow such holder or prospective holder registration rights on a parity with or senior to those granted to the Holders hereunder, other than the right to a Special Registration Statement. 

2.15 “Market Stand-Off” Agreement. If requested by the managing underwriter of the
Company’s Initial Offering, each Holder hereby agrees that such Holder shall not sell, transfer, make any short sale of, grant any option for the purchase of, or enter into any hedging or similar transaction with the same economic effect as a
sale, any Common Stock (or other securities) of the Company held by such Holder (other than those included in the registration) for a period specified by the representative of the underwriters of Common Stock (or other securities) of the Company not
to exceed one hundred eighty (180) days (subject to such extension(s) as may be required by the underwriters to publish research reports while complying with Rule 2711 of the Financial Industry Regulatory Authority, Inc.) following the
effective date of a registration statement of the Company filed under the Securities Act; provided that such agreement shall apply only to the Company’s Initial Offering; provided further that all officers and directors of the
Company and holders of at least one percent (1%) of the Company’s voting securities are bound by and have entered into similar agreements; provided further that such agreement shall provide that any discretionary waiver or
termination of the restrictions of such agreement by the Company or representative of the underwriters shall apply to the Holders on a pro-rata basis based on the number of Registrable Securities held; and provided further, that the restrictions set
forth herein shall not apply to shares purchased in the Initial Offering or to shares acquired in the public markets following effectiveness of the registration statement of the Company relating to the Initial Offering. Each Holder agrees to execute
and deliver such other agreements as may be reasonably requested by the Company or the underwriters that are consistent with the Holder’s obligations under this Section 2.15 or that are necessary to give further effect thereto. 

The Company may impose stop-transfer instructions with respect to the shares of Common Stock (or other securities) subject to the foregoing
restriction until the end of such period of restriction. 
 (a) Each Holder agrees that a legend reading substantially as follows shall be
placed on all certificates representing all Registrable Securities of each Holder (and the shares or securities of every other person subject to the restriction contained in this Section 2.15): 

“THE SECURITIES REPRESENTED BY THIS CERTIFICATE ARE SUBJECT TO A LOCK-UP PERIOD OF UP TO 180 DAYS AFTER THE EFFECTIVE DATE OF THE
ISSUER’S FIRST REGISTRATION STATEMENT FILED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, AS SET FORTH IN AN AGREEMENT BETWEEN THE COMPANY AND THE ORIGINAL HOLDER OF THESE SECURITIES, A COPY OF WHICH MAY BE OBTAINED AT THE ISSUER’S
PRINCIPAL OFFICE. SUCH LOCK-UP PERIOD IS BINDING ON TRANSFEREES OF THESE SHARES.” 

  
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 The Company shall use all reasonable efforts to cause each future holder of its securities to
enter into an agreement substantially similar to the lock-up agreement set forth in this Section 2.15. 
 2.16 Agreements to
Furnish Information. It shall be a condition precedent to the obligations of the Company to take any action pursuant to this Section 2 with respect to the Registrable Securities of any selling Holder that such Holder shall furnish to
the Company such information regarding itself, the Registrable Securities held by it, and the intended method of disposition of such securities as shall be required to effect the registration of such Holder’s Registrable Securities. Each Holder
agrees to execute and deliver such other agreements as may be reasonably requested by the Company or the underwriters that are consistent with the Holder’s obligations under Section 2.15 or that are necessary to give further effect
thereto. In addition, if requested by the Company or the representative of the underwriters of Common Stock (or other securities) of the Company, each Holder shall provide promptly such information as may be required by the Company or such
representative in connection with the completion of any public offering of the Company’s securities pursuant to a registration statement filed under the Securities Act. The obligations described in Section 2.15 and this
Section 2.16 shall not apply to a Special Registration Statement. The underwriters of the Company’s stock are intended third party beneficiaries of Sections 2.15 and 2.16 and shall have the right, power and authority
to enforce the provisions hereof as though they were a party hereto. If requested by the underwriter, each Holder agrees to execute the underwriter’s standard lock-up agreement provided that such
agreement is substantially similar to the provisions of Section 2.15. 
 2.17 Termination of Registration Rights. No
Holder shall be entitled to exercise any right provided for in this Section 2 upon the earlier of (a) the date seven (7) years after the effective date of a registration statement filed by the Company under the Securities
Act in connection with the Initial Offering or (b) with respect to any Holder, such time after the effective date of a registration statement filed by the Company under the Securities Act in connection with the Initial Offering as Rule 144
or another similar exemption under the Securities Act is available for the sale of all of such Holder’s shares without restriction. 
  

	 	3.	Covenants of the Company 

  

	 	3.1	Financial Information 

 (a) The Company shall deliver, along with a certificate of an
officer of the Company, to each Investor, together with its affiliates, that holds at least Seven Hundred Fifty Thousand (750,000) shares (as appropriately adjusted for any Recapitalizations) of Common Stock issued or issuable upon conversion
of the Shares (each a “Major Investor”), as soon as practicable, but in any event within one hundred eighty (180) days after the end of each fiscal year of the Company, a statement of operations for such fiscal year, a
balance sheet of the Company, a statement of cash flows for such fiscal year, and statement of shareholders’ equity as of the end of such year, such year-end financial reports to be in reasonable detail,
prepared in accordance with generally accepted accounting principles (“GAAP”), and audited and certified by independent public accountants of nationally recognized standing selected by the Company and approved by the
Company’s Board of Directors; and 

  
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 (b) The Company shall deliver, along with a certificate of an officer of the Company, to each
Major Investor, (i) as soon as practicable, but in any event within ninety (90) days after the end of each of the first three (3) quarters of each fiscal year of the Company, an unaudited statement of operations, statement of cash
flows for such fiscal quarter, and balance sheet for and as of the end of such fiscal quarter, including a comparison to annual budget figures for such period, (ii) as soon as practicable, but in any event within thirty (30) days after the
end of each of month, an unaudited statement of operations, statement of cash flows for such month, and balance sheet for and as of the end of such month, including a comparison to annual budget figures for such period, and (iii) the
Company’s annual budget and operating plans for each fiscal year. 
 3.2 Right of First Offer. Subject to the terms and
conditions specified in this Section 3.1(a), the Company hereby grants to each Major Investor a right of first offer with respect to future sales by the Company of its Equity Securities (as hereinafter defined). Each time the Company
proposes to offer any shares of, or securities convertible into or exercisable for any shares of, any class of its capital stock (“Equity Securities”), the Company shall first make an offering of such Equity Securities to
each Major Investor in accordance with the following provisions: 
 (a) The Company shall deliver a written notice in accordance with
Section 4.5 to the Major Investors stating (i) the Company’s bona fide intention to offer such Equity Securities, (ii) the number of such Equity Securities to be offered, and (iii) the price and terms, if any, upon
which the Company proposes to offer such Equity Securities (the “Notice”). 
 (b) Within fifteen (15) calendar
days after giving of the Notice, the Major Investor may elect in writing to purchase or obtain, at the price and on the terms specified in the Notice, up to that portion of such Equity Securities which equals the proportion that the number of shares
of Common Stock issued and held, or issuable upon conversion of the Shares then held, by such Major Investor bears to the total number of shares of Common Stock of the Company then outstanding (assuming full conversion and exercise of all
convertible or exercisable securities). The Company shall promptly, in writing, inform each Major Investor that purchases all the shares available to it (a “Fully-Exercising Investor”)
of any other Major Investor’s failure to do likewise. During the ten-day period commencing after such information is given, each Fully-Exercising Investor shall be
entitled to obtain that portion of the Equity Securities for which Major Investors were entitled to subscribe but which were not subscribed for by the Major Investors (the “Overallotment Right”), such portion equal to the
proportion that the number of shares of Common Stock issued and held, or issuable upon conversion of Shares then held, by such Fully-Exercising Investor bears to the total number of shares of Common Stock
issued and held, or issuable upon conversion of the Shares then held, by all Fully-Exercising Investors who wish to purchase some of the unsubscribed shares; provided, however, if any Wellington
Investor chooses not to purchase all the shares available to it, then the other Wellington Investors shall have the right to purchase such shares not subscribed for by such Wellington Investor, in preference to the Overallotment Right. 

  
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 (c) If all Equity Securities that the Major Investors are entitled to obtain pursuant to
Section 3.2(b) are not elected to be obtained as provided in Section 3.2(b) hereof, the Company may, during the sixty (60) day period following the expiration of the period provided in Section 3.2(b) hereof,
offer the remaining unsubscribed portion of such Equity Securities to any person or persons at a price not less than, and upon terms no more favorable to the offeree than those specified in the Notice. If the Company does not enter into an agreement
for the sale of the Equity Securities within such period, or if such agreement is not consummated within sixty (60) days of the execution thereof, the right provided hereunder shall be deemed to be revived and such Equity Securities shall not
be offered unless first reoffered to the Major Investors in accordance herewith. 
 (d) The right of first offer in this
Section 3.1(a) shall not be applicable to (i) issuances of shares of capital stock of the Company that are not deemed to be “Additional Stock” pursuant to Article IV, Section B.4(d)(ii) of the Company’s Amended and
Restated Articles of Incorporation, as the same may be amended (the “Restated Charter”) and (ii) shares of the Company’s Series F Preferred Stock sold pursuant Purchase Agreement. 

3.3 Confidentiality of Records. Each Investor agrees to use reasonable care to keep confidential any information furnished to such
Investor that the Company identifies as being confidential or proprietary (so long as such information is not in the public domain), except that such Investor may disclose such proprietary or confidential information (i) to its attorneys,
accountants, consultants, and other professionals to the extent necessary to obtain their services in connection with monitoring its investment in the Company; (ii) to any prospective purchaser of any Registrable Securities from such Investor,
if such prospective purchaser agrees to be bound by the provisions of this Section 3.3; (iii) to any existing or prospective affiliate, partner, member, stockholder, or wholly owned subsidiary of such Investor in the ordinary
course of business (or to their affiliates, partners, members, stockholders, or wholly owned subsidiaries, or their attorneys, accountants, consultants, and other professionals to the extent necessary to obtain their services in the case of a
Wellington Investor, the partners of such Wellington Investor’s partners) provided that such Investor informs such Person that such information is confidential and directs such Person to maintain the confidentiality of such information;
(iv) as may otherwise be required by law, provided that the Investor promptly notifies the Company of such disclosure, takes reasonable steps to minimize the extent of any such required disclosure and discloses the minimum amount of information
necessary to satisfy such legal requirement; (v) at such time as it enters the public domain through no fault of such Investor; (vi) that is communicated to it free of any obligation of confidentiality; or (vii) that is developed by
Investor or its agents independently of and without reference to any confidential information communicated by the Company. 
 3.4
Reservation of Common Stock. The Company will at all times reserve and keep available, solely for issuance and delivery upon the conversion of its Preferred Stock, all Common Stock issuable from time to time upon such conversion. 

3.5 Equity Awards. Unless otherwise approved by the Board of Directors, including at least three (3) of the directors designated by
InterWest Partners X, LP, KPCB Holdings, Inc., Healthcare Royalty Partners II, L.P. or Valence Advantage Life Sciences Fund II, L.P. (or any of their respective affiliates), 

  
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 (a) all stock options and other stock equivalents issued after the date of this Agreement to
employees, directors, consultants and other service providers of the Company subject to the Company’s right of repurchase on unvested shares at cost, shall be subject to vesting as follows: (a) twenty-five percent (25%) of such stock
shall vest at the end of the first year following the earlier of the date of issuance or such person’s services commencement date with the Company, and (b) seventy-five percent (75%) of such stock shall vest monthly over the remaining
three (3) years; and 
 (b) if employees of the Company are permitted to exercise unvested stock options, the repurchase option with
respect to the shares shall provide that upon termination of the employment of the shareholder, with or without cause, the Company or its assignee (to the extent permissible under applicable securities laws) shall retain the option to repurchase at
cost any unvested shares held by such shareholder. 
 3.6 Directors’ and Officers’ Insurance and Indemnification. The
Company agrees to use reasonable efforts to promptly obtain and maintain in full force and effect customary and standard director and officer liability insurance coverage in an appropriate amount and in a form as determined by the Board of
Directors. In addition, as determined by the Board of Directors, the Company shall enter into and at all times maintain indemnification agreements with each of its directors to indemnify such directors to the maximum extent permissible under
applicable law. 
 3.7 Inspection Rights. Each Major Investor shall have the right to visit and inspect any of the properties of the
Company or any of its subsidiaries, and to discuss the affairs, finances and accounts of the Company or any of its subsidiaries with its officers, and to review such information as is reasonably requested all at such reasonable times and as often as
may be reasonably requested; provided, however, that the Company shall not be obligated under this Section 3.7 with respect to a competitor of the Company or with respect to information which the Board of Directors determines in
good faith is confidential or attorney-client privileged and should not, therefore, be disclosed. 
 3.8 Invention Assignment and
Confidentiality Agreement. The Company shall require all employees and consultants to execute and deliver an Invention Assignment and Confidentiality Agreement substantially in a form approved by the Company’s counsel or Board of Directors.

 3.9 Protective Provisions Requiring Board Consent 

For so long as at least 1,000,000 shares of Series D Preferred Stock (as appropriately adjusted for any Recapitalizations) or 1,000,000
shares of Series E Preferred Stock (as appropriately adjusted for any Recapitalizations) or 1,000,000 shares of Series F Preferred Stock (as appropriately adjusted for any Recapitalizations) remain outstanding, the Company will not, without
obtaining the consent of a majority of the directors then serving on the Board of Directors: 

  
 20 

 (a) authorize the issuance of indebtedness for borrowed money of greater than two hundred fifty
thousand dollars ($250,000) outside of the ordinary course of business; 
 (b) own or permit any company affiliated with the Company to own
any stock or other securities of any affiliate company or corporation, partnership or entity; 
 (c) hire any employee with an annual
compensation package of greater than two hundred thousand dollars ($200,000); 
 (d) pledge or grant a security interest in any assets of
the Company; 
 (e) sell, transfer, pledge, or encumber technology or intellectual property, other than licenses granted in the ordinary
course of business; 
 (f) make guarantees of third-party loans to employees or of obligations of wholly owned subsidiaries, except in the
ordinary course of business; 
 (g) increase the number of shares authorized under the Company’s 2005 Stock Incentive Plan or any
successor to the Company’s 2005 Stock Incentive Plan; 
 (h) enter into any agreements (other than employment agreements), including
but not limited to leases, that obligate the Company to make aggregate annual payments in excess of fifty thousand dollars ($50,000); 
 (i)
enter into any material transactions with any director or management employee or immediate families or affiliates thereof; 
 (j) amend the
articles of incorporation or bylaws of the Company; or 
 (k) establish or invest in any subsidiary or joint venture. 

3.10 Board Consent for Exceptions to Conversion Price Adjustments. Pursuant to Article IV, Section B.4(d)(ii)(A), (C), (F), (G) or
(J) of the Restated Charter, certain issuances of securities by the Company (each, an “Approvable Issuance” and, together, the “Approvable Issuances”) will not be deemed to be issuances of
“Additional Stock” (as defined in the Restated Charter) if such Approvable Issuances are approved by a majority of the directors then serving on the Board of Directors (the “Majority Director Vote”). Notwithstanding
the foregoing, the Company will not consummate an Approvable Issuance (even if the Majority Director Vote has been obtained) unless the Company (A) agrees to treat the Approvable Issuance as an issuance of Additional Stock that causes a
Conversion Price (as defined in the Restated Charter) adjustment or (B) obtains the consent of each Preferred Designee (as defined in the Restated Charter) designated by a series of Preferred Stock that would be subject to a Conversion Price
(as defined in the Restated Charter) adjustment but for such Majority Director Vote. 

  
 21 

 3.11 Approval for Acquisition or Dissolution. In addition to any other vote or consent
required by law, the Company shall not (by amendment, merger, consolidation or otherwise, and either directly or indirectly by subsidiary) without first obtaining the approval (by vote or written consent as provided by law) of the holders of at
least sixty-five percent (65%) of the Preferred Stock then outstanding, voting together as a single class on an as converted to common basis, consummate an Acquisition (as defined in the Restated Charter) or a dissolution, liquidation or
winding up of the Company. 
 3.13 Termination of Certain Covenants. The covenants set forth in this Section 3 (other than
the covenant set forth in Section 3.2) shall terminate and be of no further force or effect upon the earlier of (a) the consummation of the sale of securities pursuant to a registration statement filed by the Company under the
Securities Act in connection with the Initial Offering (as defined in this Agreement), or (b) an “Acquisition” of the Company (as defined in the Company’s Restated Charter). The covenant set forth in Section 3.2 shall
terminate and be of no further force or effect upon the earlier of (a) the consummation of the Initial Offering (as defined in the Company’s Restated Charter), or (b) an Acquisition of the Company. 

 

	 	4.	Miscellaneous 

 4.1 Successors and Assigns. Except as otherwise provided herein,
the terms and conditions of this Agreement shall inure to the benefit of and be binding upon the respective successors and assigns of the parties (including permitted transferees of any shares of Registrable Securities). Nothing in this Agreement,
express or implied, is intended to confer upon any party other than the parties hereto or their respective successors and assigns any rights, remedies, obligations, or liabilities under or by reason of this Agreement, except as expressly provided in
this Agreement. 
 4.2 Governing Law. This Agreement shall be governed by and construed under the laws of the State of California as
applied to agreements among California residents entered into and to be performed entirely within California. The parties agree that any action brought by any party under or in relation to this Agreement, including without limitation to interpret or
enforce any provision of this Agreement, shall be brought in, and each party agrees to and does hereby submit to the jurisdiction and venue of, any state or federal court located in the County of San Francisco, California. 

4.3 Counterparts; Facsimile Signatures. This Agreement may be executed in any number of counterparts, each of which shall be deemed an
original, but all of which together shall constitute one and the same instrument. This Agreement may be executed and delivered by facsimile or other electronic transmission and upon such delivery the facsimile or other electronic transmission
signature will be deemed to have the same effect as if the original signature had been delivered to the other parties. 
 4.4 Titles and
Subtitles. The titles and subtitles used in this Agreement are used for convenience only and are not to be considered in construing or interpreting this Agreement. 

  
 22 

 4.5 Notices. Unless otherwise provided, any notice required or permitted under this
Agreement shall be given in writing and shall be deemed effectively given upon personal delivery to the party to be notified, one (1) business day after delivery by confirmed facsimile transmission or nationally recognized overnight courier
service, three (3) business days after deposit with the United States Post Office, or three (3) business days after being sent by registered or certified mail, postage prepaid and addressed to the party to be notified at the address (and
with such copies, which shall not constitute notice) indicated for such party on the signature page hereof, or at such other address as such party may designate by ten (10) days’ advance written notice to the other parties. 

4.6 Attorney’s Fees. If any action at law or in equity is necessary to enforce or interpret the terms of this Agreement, the
prevailing party shall be entitled to reasonable attorneys’ fees, costs and necessary disbursements in addition to any other relief to which such party may be entitled. 

4.7 Amendments and Waivers. Any term of this Agreement may be amended and the observance of any term of this Agreement may be waived
(either generally or in a particular instance and either retroactively or prospectively), only with the written consent of the Company and the Requisite Percentage; provided, however, that the rights and privileges with respect to the
Wellington Investors in Sections 2.15, 3.1, 3.2, 3.7 and 3.8 and this proviso may be amended or waived only with the written consent of the Holders of at least seventy-five percent (75%) of the Registrable
Securities then outstanding and held by the Wellington Investors. Notwithstanding the foregoing, this Agreement may not be amended, modified or terminated and the observance of any term hereunder may not be waived with respect to any Investor
without the written consent of such Investor unless such amendment, modification, termination or waiver applies to all Investors in the same fashion. The Company shall give prompt written notice of any amendment, modification or termination hereof
or waiver hereunder to any party hereto that did not consent in writing to such amendment, modification, termination or waiver. Any amendment or waiver effected in accordance with this Section 4.7 shall be binding upon each holder of any
Registrable Securities then outstanding, each future holder of all such Registrable Securities, the Investors, and the Company. 
 4.8
Effect of Amendment or Waiver. Each Investor acknowledges that by the operation of Section 4.7 hereof the Requisite Percentage will have the right and power to diminish or eliminate all rights of such Investor under this Agreement,
except with respect to the limitation set forth in the proviso of the first sentence of Section 4.7 with respect to the Wellington Investors. 

4.9 Severability. In the event one or more of the provisions of this Agreement should, for any reason, be held to be invalid, illegal
or unenforceable in any respect, such invalidity, illegality or unenforceability shall not affect any other provisions of this Agreement, and this Agreement shall be construed as if such invalid, illegal or unenforceable provision had never been
contained herein. 
 4.10 Aggregation of Stock. All shares of Registrable Securities held or acquired by affiliated entities or
persons shall be aggregated together for the purpose of determining the availability of any rights under this Agreement. For purposes of this Agreement, (a) each Wellington Investor shall be deemed to be an “affiliate” of or
“affiliated with” each other Wellington Investor, and (b) an entity that is an “affiliate” of or “affiliated with” a 

  
 23 

 
Wellington Investor shall not be deemed to be an “affiliate” of or “affiliated with” any other Wellington Investor unless such entity is a Wellington Investor (and, for the
avoidance of doubt, an “affiliate” of such entity shall not be deemed an “affiliate” of or “affiliated with” any Wellington Investor solely by virtue of being an “affiliate” of or “affiliated with”
such entity). 
 4.11 Entire Agreement. This Agreement and the Exhibits hereto, along with the Purchase Agreement and
the other documents delivered pursuant thereto constitute the full and entire understanding and agreement between the parties with regard to the subjects hereof and thereof and no party shall be liable or bound to any other in any manner by any oral
or written representations, warranties, covenants and agreements except as specifically set forth herein and therein. Each party expressly represents and warrants that it is not relying on any oral or written representations, warranties, covenants
or agreements outside of this Agreement. 
 4.12 Delays or Omissions. It is agreed that no delay or omission to exercise any right,
power or remedy accruing to any party, upon any breach, default or noncompliance by another party under this Agreement shall impair any such right, power or remedy, nor shall it be construed to be a waiver of any such breach, default or
noncompliance, or any acquiescence therein, or of or in any similar breach, default or noncompliance thereafter occurring. It is further agreed that any waiver, permit, consent or approval of any kind or character on any party’s part of any
breach, default or noncompliance under this Agreement or any waiver on such party’s part of any provisions or conditions of the Agreement must be in writing and shall be effective only to the extent specifically set forth in such writing. All
remedies, either under this Agreement by law, or otherwise afforded to any party, shall be cumulative and not alternative. 
 4.13 Prior
Agreement Superseded. 
 Upon the effectiveness of this Agreement, the Prior Rights Agreement shall be superseded and replaced in its
entirety by this Agreement. Upon such effectiveness, all provisions of, rights granted and covenants made in the Prior Rights Agreement are hereby waived, released and superseded in their entirety by the provisions hereof and shall have no further
force or effect. 
 [Remainder of page intentionally left blank; signature page follows.] 

  
 24 

 IN WITNESS WHEREOF, the parties have executed this Agreement as of the date first above written.

  

			
	COMPANY:
	
	INVUITY, INC.
		
	By:		 /s/ Philip Sawyer

			Philip Sawyer, Chief Executive Officer

			
		
	Address:		 444 De Haro Street
 San Francisco, California
94107

 SERIES F FOURTH AMENDED AND
RESTATED INVESTOR RIGHTS AGREEMENT 
 SIGNATURE
PAGE FOR INVUITY, INC. 

 
			
	KEY HOLDER:
	
	WOODBERRY-TRAUNER TRUST
		
	By:		 /s/ Kenneth Trauner

	Name:		Kenneth Trauner
	Title:		Trustee

 SERIES F FOURTH AMENDED AND
RESTATED INVESTOR RIGHTS AGREEMENT 
 SIGNATURE
PAGE FOR INVUITY, INC. 

 
	
	KEY HOLDER:
	
	ALEX VAYSER
	
	 /s/ Alex Vayser

	
	KEVIN B. MAY AND JODIE C. MAY, HUSBAND AND WIFE AS COMMUNITY
PROPERTY WITH RIGHT OF SURVIVORSHIP
	
	 /s/ Alex Vayser

	By: Alex Vayser, Proxy Holder

 SERIES F FOURTH AMENDED AND
RESTATED INVESTOR RIGHTS AGREEMENT 
 SIGNATURE
PAGE FOR INVUITY, INC. 

 
			
	INVESTORS:
	
	Hadley Harbor Master Investors (Cayman) L.P.
	
	 By:   Wellington Management Company LLP, as investment adviser

		
	By:		 /s/ Emily D. Babalas

	Name:		Emily D. Babalas
	Title:		Vice President and Counsel
	
	The Hartford Capital Appreciation Fund
	
	 By:   Wellington Management Company LLP, as investment adviser

		
	By:		 /s/ Emily D. Babalas

	Name:		Emily D. Babalas
	Title:		Vice President and Counsel
	
	With a copy to:
	
	WilmerHale
	60 State St.
	Boston, MA 02482
	 Attn: Jason L. Kropp

jason.kropp@wilmerhale.com

	Facsimile: (617) 526-5000

 SERIES F FOURTH AMENDED AND
RESTATED INVESTOR RIGHTS AGREEMENT 
 SIGNATURE
PAGE FOR INVUITY, INC. 

 
			
	
	INVESTORS:
	
	ERIC W. ROBERTS
		
	By:		 /s/ Eric W. Roberts

	Name:		Eric W. Roberts
	
	VALENCE CDK SPV, L.P.
		
	By:		 /s/ Eric W. Roberts

	Name:		Eric W. Roberts
	Title:		Managing Member of General Partner

 SERIES F FOURTH AMENDED AND
RESTATED INVESTOR RIGHTS AGREEMENT 
 SIGNATURE
PAGE FOR INVUITY, INC. 

 
			
	INVESTORS:
	
	HEALTHCARE ROYALTY PARTNERS II, L.P.
	
	 By:   HealthCare Royalty GP II, LLC, its General Partner

		
	By:		 /s/ Gregory B. Brown

	Name:		Gregory B. Brown
	Title:		Founding Managing Director

 SERIES F FOURTH AMENDED AND
RESTATED INVESTOR RIGHTS AGREEMENT 
 SIGNATURE
PAGE FOR INVUITY, INC. 

 
			
	INVESTORS:
	
	CDK ASSOCIATES, L.L.C.
		
	By:		 /s/ Karen Cross

	Name:		Karen Cross
	Title:		Treasurer

 SERIES F FOURTH AMENDED AND
RESTATED INVESTOR RIGHTS AGREEMENT 
 SIGNATURE
PAGE FOR INVUITY, INC. 

 
			
	INVESTORS:
	
	KPCB HOLDINGS, INC.
		
	By:		 /s/ Paul M. Vronsky

	Name:		Paul M. Vronsky
	Title:		General Counsel

 SERIES F FOURTH AMENDED AND
RESTATED INVESTOR RIGHTS AGREEMENT 
 SIGNATURE
PAGE FOR INVUITY, INC. 

 
			
	INVESTORS:
	
	INTERWEST PARTNERS X, LP
	
	 By:  InterWest Management Partners X, LLC, its general partner

		
	By:		 /s/ W. Stephen Holmes

	Name:		W. Stephen Holmes
	Title:		Managing Director

 SERIES F FOURTH AMENDED AND
RESTATED INVESTOR RIGHTS AGREEMENT 
 SIGNATURE
PAGE FOR INVUITY, INC. 

 
			
	INVESTORS:
	
	COVENANT PROPERTIES, LLC
		
	By:		 /s/ Sidney J. Jansma III

	Name:		Sidney J. Jansma III
	Title:		Manager
	
	HERITAGE HOLDING CO. LLC
		
	By:		 /s/ Sidney J. Jansma III

	Name:		Sidney J. Jansma III
	Title:		Manager
	
	LEGACY LIFE SCIENCES, LLC
		
	By:		 /s/ Sidney J. Jansma III

	Name:		Sidney J. Jansma III
	Title:		Manager

 SERIES F FOURTH AMENDED AND
RESTATED INVESTOR RIGHTS AGREEMENT 
 SIGNATURE
PAGE FOR INVUITY, INC. 

 
			
	INVESTORS:
	
	HELIX FOUNDERS FUND, L.P.
	
	By: HFF G.P., L.L.C., its General Partner
		
	By:		 /s/ Evgeny Zaytsev

	Name:		Evgeny Zaytsev
	Title:		Manager

 SERIES F FOURTH AMENDED AND
RESTATED INVESTOR RIGHTS AGREEMENT 
 SIGNATURE
PAGE FOR INVUITY, INC. 

 
			
	INVESTORS:
	
	WINDHAM-INV INVESTMENT I, LLC
	
	 By:  WINDHAM VENTURE MANAGEMENT, LLC, Managing Member

		
	By:		 /s/ Adam E. Fine

			Adam E. Fine
			Its: Managing Member

  

			
	WINDHAM LIFE SCIENCES PARTNERS, L.P.
	
	 By:  Windham Life Sciences Partners General Partner, LLC

		
	By:		 /s/ Adam Fine

	Name:		Adam Fine
	Title:		Managing Member

 SERIES F FOURTH AMENDED AND
RESTATED INVESTOR RIGHTS AGREEMENT 
 SIGNATURE
PAGE FOR INVUITY, INC. 

 
			
	INVESTORS:
	
	RIVERROAD CAPITAL PARTNERS, LLC
		
	By:		 /s/ Gregory T. Lucier

	Name:		Gregory T. Lucier
	Title:		Managing Member

 SERIES F FOURTH AMENDED AND
RESTATED INVESTOR RIGHTS AGREEMENT 
 SIGNATURE
PAGE FOR INVUITY, INC. 

 INVUITY, INC. 

OMNIBUS AMENDMENT TO SERIES F PREFERRED STOCK PURCHASE AGREEMENT AND 

INVESTOR RIGHTS AGREEMENT 

This Omnibus Amendment to Series F Preferred Stock Purchase Agreement and Investor Rights Agreement is made as of March 4, 2015 (this
“Amendment”), by and among Invuity, Inc. (the “Company”) and the undersigned individuals and entities listed on Schedule A (the “Investors”) to that certain Fourth Amended and
Restated Investor Rights Agreement, dated February 6, 2015 (the “Investor Rights Agreement”), by and the Company and the Investors. All capitalized terms used but not defined herein shall have the meaning ascribed to
them in the Investor Rights Agreement or the Purchase Agreement (as defined below), as applicable. 
 WHEREAS, the Company has
entered into a Series F Preferred Stock Purchase Agreement dated February 6, 2015 (the “Purchase Agreement”) with certain of the Investors; 

WHEREAS, in connection with the sale and purchase of Series F Preferred Stock pursuant to the Purchase Agreement, the Company has also
entered into the Investor Rights Agreement with the Investors; 
 WHEREAS, the Purchase Agreement contemplated the sale and issuance
of an aggregate of 26,200,000 shares of Series F Preferred Stock in one Closing; 
 WHEREAS, the Company and the Investors mutually
wish to maximize the amount of funding obtained under the Purchase Agreement by allowing for the sale of an additional 4,410,000 shares of Series F Preferred Stock, and allowing additional Closings for a period of time expiring on March 13,
2015; 
 WHEREAS, Section 6.11 of the Purchase Agreement provides that the Purchase Agreement may be amended or modified only
with the written consent of the Company and holders of a majority of the then outstanding Shares (treated as if converted and including any Conversion Shares); 

WHEREAS, Section 4.7 of the Investor Rights Agreement provides that any term of the Investor Rights Agreement may be amended with
the written consent of the Company and the holders of at least 65% of the Registrable Securities then outstanding (excluding any Key Holder Shares); and 

WHEREAS, the Company and the undersigned Investors, representing the parties necessary to amend the Purchase Agreement and the Investor
Rights Agreement, mutually wish to make certain amendments to the Purchase Agreement and Investor Rights Agreement. 
 NOW,
THEREFORE, in consideration of the mutual agreements contained herein, the Company and the undersigned Investors agree as follows: 
 1.
Amendment to Recitals of the Purchase Agreement. Effective as of the date hereof, and pursuant to Section 6.11 of the Purchase Agreement, the first recital of the Purchase Agreement is hereby amended and restated in its entirety to read
as follows: 
 “WHEREAS, the Company has authorized the sale and issuance of an aggregate 30,610,000 shares of its Series F
Preferred Stock (the “Shares”);” 
 2. Amendment to Section 1.1(b) of the Purchase Agreement.
Effective as of the date hereof, and pursuant to Section 6.11 of the Purchase Agreement, Section 1.1(b) of the Purchase Agreement is hereby amended and restated in its entirety to read as follows: 

“Subject to the terms and conditions of this Agreement, each Investor agrees to purchase and the Company agrees to sell and issue to each
Investor, severally and not jointly, that number of Shares set forth opposite such Investor’s name on Schedule A hereto at a price of $0.7754 per share.” 

 3. Amendment to Section 1.2 of the Purchase Agreement. Effective as of the date
hereof, and pursuant to Section 6.11 of the Purchase Agreement, Section 1.2 of the Purchase Agreement is hereby amended and restated in its entirety to read as follows: 

“1.2 Closings. 
 (a)
The purchase and sale of the Shares shall take place at one or more closings. The initial closing (the “Closing”) shall take place at the offices of Wilson Sonsini Goodrich & Rosati, Professional Corporation, One
Market, Spear Tower, Suite 3300, San Francisco, CA, 94105, on February 6, 2014, or at such other time and place as the Company and the Investors acquiring in the aggregate a majority of the Shares to be purchased at the Closing shall mutually
agree, either orally or in writing. At the Closing, the Company shall deliver to each Investor the various certificates, instruments and documents referred to in Section 4 below. As soon as practicable after the Closing, the Company
shall deliver to each Investor a certificate representing the Shares that such Investor is purchasing against payment of the purchase price therefor by check, wire transfer or any combination thereof. 

(b) If less than all of the Shares are sold and issued at the Closing, then, subject to the terms and conditions of this Agreement, the Company
may sell and issue at one or more subsequent closings (each, a “Subsequent Closing”), at any time through March 13, 2015, up to the balance of the unissued Shares to such persons or entities as may be approved by the
Company in its sole discretion. Any such sale and issuance in a Subsequent Closing shall be on the same terms and conditions as those contained herein, and such persons or entities shall, upon execution and delivery of the relevant signature pages,
become parties to, and be bound by, this Agreement and the Ancillary Agreements (as defined below, and together with this Agreement, the “Agreements”), without the need for an amendment to any of the Agreements except to add
such person’s or entity’s name to the appropriate exhibit to such Agreements, and shall have the rights and obligations hereunder and thereunder, in each case as of the date of the applicable Subsequent Closing. Each Subsequent Closing
shall take place at such date, time and place as shall be approved by the Company in its sole discretion. 
 (c) Immediately after each
Subsequent Closing, the Schedule of Investors will be amended to list the Investors purchasing Shares hereunder and the number of Shares issued to each Investor hereunder at each such Subsequent Closing. The Company will furnish to each Investor
copies of the amendments to the Schedule of Investors referred to in the preceding sentence.” 
 4. Amendment to Section 5 of
the Purchase Agreement. Effective as of the date hereof, and pursuant to Section 6.11 of the Purchase Agreement, the first paragraph of Section 5 and Sections 5.1 and 5.2 of the Purchase Agreement are hereby amended and restated in
their entirety to read as follows: 
 “Conditions of the Company’s Obligations at the Closing. The obligations of the
Company at the Closing or a Subsequent Closing to each Investor under this Agreement are subject to the fulfillment on or before the Closing or such Subsequent Closing of each of the following conditions by each Investor participating in the Closing
or such Subsequent Closing: 
 5.1 Representations and Warranties. The representations and warranties of each Investor participating
in the Closing or such Subsequent Closing contained in Section 3 shall be true and correct in all respects on and as of the Closing or such Subsequent Closing with the same effect as though such representations and warranties had been
made on and as of the Closing or such Subsequent Closing. 

 5.2 Performance of Obligations. Such Investors shall have performed and complied with all
agreements and conditions herein required to be performed or complied with by such Investors on or before the Closing or such Subsequent Closing.” 

5. Amendment to Section 6.2 of the Purchase Agreement. Effective as of the date hereof, and pursuant to Section 6.11 of the
Purchase Agreement, Section 6.2 of the Purchase Agreement is hereby amended and restated in its entirety to read as follows: 

“6.2 Survival of Warranties. The warranties, representations and covenants of the Company and each Investor contained in or made
pursuant to this Agreement shall survive the execution and delivery of this Agreement and the Closing or Subsequent Closing, as applicable.” 

6. Amendment to Section 6.11(a) of the Purchase Agreement. Effective as of the date hereof, and pursuant to Section 6.11 of
the Purchase Agreement, Section 6.11(a) of the Purchase Agreement is hereby amended and restated in its entirety to read as follows: 

“(a) This Agreement may be amended or modified only upon the written consent of the Company and holders of a majority of the then
outstanding Shares (treated as if converted and including any Conversion Shares) (the “Requisite Percentage”); provided, however, that Investors purchasing shares in a Subsequent Closing may become parties to this
Agreement in accordance with Section 1.2 without any amendment of this Agreement pursuant to this paragraph or any consent or approval of any other Investor.” 

7. Amendment to Section 3.9(h) of the Investor Rights Agreement. Effective as of the date hereof, and pursuant to Section 4.7
of the Investor Rights Agreement, Section 3.9(h) of the Investor Rights Agreement is hereby amended and restated in its entirety to read as follows: 

“(h) enter into any agreements (other than employment agreements), including but not limited to leases, that obligate the Company to make
aggregate annual payments in excess of two hundred fifty thousand dollars ($250,000);” 
 8. Full Force and Effect. To the
extent not expressly amended hereby, the Purchase Agreement and Investor Rights Agreement remain in full force and effect. 
 9. Entire
Agreement. This Amendment, together with the Purchase Agreement and Investor Rights Agreement (to the extent each is not amended hereby) and all exhibits thereto, represent the entire agreement of the parties and shall supersede any and all
previous contracts, arrangements or understandings between the parties with respect to the subject matter herein. 
 10. Governing
Law. This Amendment shall be governed by and construed and interpreted under the laws of the State of California without reference to conflicts of law principles. 

11. Modification. This Amendment may not be altered, amended or modified in any way except in accordance with the relevant provisions
of the Purchase Agreement and the Investor Rights Agreement, as applicable. Waiver of any term or provision of this Amendment or forbearance to enforce any term or provision by any party shall not constitute a waiver as to any subsequent breach or
failure of the same term or provision or a waiver of any other term or provision of this Amendment. 
 12. Counterparts. This
Amendment may be executed in counterparts, each of which shall be declared an original, but all of which together shall constitute one and the same instrument. 

13. Facsimile. This Amendment may be executed by facsimile. 

[Signature Page Follows] 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 COMPANY:
  

INVUITY, INC.

		
	By:	 	/s/ Philip Sawyer
	 Philip Sawyer, Chief Executive Officer

	
	 Address: 444 De Haro Street

San Francisco, California 94107

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

Hadley Harbor Master Investors (Cayman) L.P.
  

By: Wellington Management Company LLP, as investment adviser

		
	By:	 	/s/ Steven M. Hoffman
	Name: Steven M. Hoffman
	Title: Managing Director and Counsel

  

			
	 The Hartford Capital Appreciation Fund
  

By: Wellington Management Company LLP, as investment adviser

		
	By:	 	/s/ Steven M. Hoffman
	Name: Steven M. Hoffman
	Title: Managing Director and Counsel

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

RIVERROAD CAPITAL PARTNERS, LLC

		
	By:	 	/s/ Gregory T. Lucier
	Name: Gregory T. Lucier
	Title: Managing Member

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

ERIC W. ROBERTS

		
	By:	 	/s/ Eric W. Roberts
	Name: Eric W. Roberts

  

			
	VALENCE CDK SPV, L.P.
		
	By:	 	/s/ Eric W. Roberts
	Name: Eric W. Roberts
	Title: Managing Member of General Partner

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

ROBERTSON REVOCABLE TRUST

		
	By:		/s/ Sanford R. Robertson

 
			
		
	Name:		Sanford R. Robertson

 
			
		
	Title:		Trustee

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

HEALTHCARE ROYALTY PARTNERS II, L.P.
  

By: HealthCare Royalty GP II, LLC, its General Partner

		
	By:	 	/s/ Gregory B. Brown
	Name: Gregory B. Brown
	Title: Founding Managing Director

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

CDK ASSOCIATES, L.L.C.

		
	By:	 	/s/ Karen Cross
	Name: Karen Cross
	Title: Treasurer

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

KPCB HOLDINGS, INC.

		
	By:		/s/ Paul M. Vronsky

 
			
		
	Name:		Paul M. Vronsky

 
			
		
	Title:		General Counsel

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

INTERWEST PARTNERS X, LP
  

By: InterWest Management Partners X, LLC, its general partner

		
	By:		/s/ Khaled A. Nasr

 
			
		
	Name:		Khaled A. Nasr

 
			
		
	Title:		Venture Member

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

THE MARC R. BENIOFF REVOCABLE TRUST U/A/D 12/3/2004

		
	By:		/s/ Marc R. Benioff

 
			
		
	Name:		Marc R. Benioff

 
			
		
	Title:		Trustee

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

ALAFI CAPITAL COMPANY, LLC

		
	By:		/s/ Moshe Alafi

 
			
		
	Name:		Moshe Alafi

 
			
		
	Title:		Managing Partner

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

THE FRIED LIVING TRUST DATED 1-3-2008, ELIOT FRIED AND CYNTHIA FRIED AS TRUSTEES

		
	By:		/s/ Eliot M. Fried

 
			
		
	Name:		Eliot M. Fried

 
			
		
	Title:		Trustee

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

COVENANT PROPERTIES, LLC

		
	By:		/s/ Sidney J. Jansma III

 
			
		
	Name:		Sidney J. Jansma

 
			
		
	Title:		Manager

  

			
	HERITAGE HOLDING CO. LLC
		
	By:		/s/ Sidney J. Jansma III

 
			
		
	Name:		Sidney J. Jansma

 
			
		
	Title:		Manager

  

			
	LEGACY LIFE SCIENCES, LLC
		
	By:		/s/ Sidney J. Jansma III

 
			
		
	Name:		Sidney J. Jansma

 
			
		
	Title:		Manager

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

HELIX FOUNDERS FUND, L.P.
  

By: HFF G.P., L.L.C., its General Partner

		
	By:		/s/ Evgeny V. Zaytsev

 
			
		
	Name:		Evgeny V. Zaytsev

 
			
		
	Title:		Member

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

WINDHAM-INV INVESTMENT I, LLC
  

By: WINDHAM VENTURE MANAGEMENT, LLC, Managing Member

		
	By:		/s/ Lindsay Redfield POA
			Adam E. Fine
			Its: Managing Member

  

			
	 WINDHAM LIFE SCIENCES PARTNERS, L.P.
  

By: Windham Life Sciences Partners General Partner, LLC

		
	By:		/s/ Lindsay Redfield POA
	Name: Adam Fine
	Title: Managing Member

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 INVESTOR:
  

RICHARDSON FAMILY TRUST

		
	By:		/s/ Stephen Richardson
			Stephen Richardson, Co-Trustee
		
	By:		/s/ Kimberly Richardson
			Kimberly Richardson, Co-Trustee

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 KEY HOLDER:
  

WOODBERRY-TRAUNER TRUST

		
	By:		/s/ Ken Trauner

 
			
		
	Name:		Ken Trauner

 
			
		
	Title:		Trustee

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights Agreement 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 KEY HOLDER:
  

ALEX VAYSER

	
	/s/ Alex Vayser

  

			
	KEVIN B. MAY AND JODIE C. MAY, HUSBAND AND WIFE AS COMMUNITY PROPERTY WITH RIGHT OF SURVIVORSHIP
	
	/s/ Alex Vayser
	By: Alex Vayser, Proxy Holder

  
 Invuity, Inc.
– Signature Page to Omnibus Amendment to 
 Series F Preferred Stock Purchase Agreement and Investor Rights AgreementEX-4.3

 Exhibit 4.3 

THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “1933 ACT”), OR ANY APPLICABLE STATE SECURITIES LAWS,
AND MAY NOT BE SOLD OR TRANSFERRED UNLESS SUCH SALE OR TRANSFER IS IN ACCORDANCE WITH THE REGISTRATION REQUIREMENTS OF SUCH ACT AND APPLICABLE LAWS OR SOME OTHER EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF SUCH ACT AND APPLICABLE LAWS IS
AVAILABLE WITH RESPECT THERETO. 
 PREFERRED STOCK PURCHASE WARRANT 

 

			
	Warrant No. WB-1		Number of Shares: a maximum of 271,221
			Series B Preferred Stock
			Subject to determination as set for the below

 INVUITY, INC. 

Effective as of September 15, 2008 

Void after September 15, 2018 

1. Issuance. This Preferred Stock Purchase Warrant (the “Warrant”) is issued to LIGHTHOUSE CAPITAL PARTNERS VI,
L.P. by INVUITY, INC., a California corporation (hereinafter with its successors called the “Company”). 
 2.
Purchase Price; Number of Shares. 
 (a) The registered holder of this Warrant (the “Holder”), is entitled
upon surrender of this Warrant with the subscription form annexed hereto duly executed, at the principal office of the Company, to purchase from the Company, at a price per share of $0.9304 (the “Purchase Price”), up to a maximum of
271,221 fully paid and nonassessable shares of the Company’s Series B Preferred Stock, (the “Preferred Stock”). Commencing on the date hereof, 110,000 (the “Exercise Quantity”) of shares of Preferred Stock are
immediately available for purchase hereunder. 
 (b) On the Commitment Termination Date, or such earlier termination of this Warrant
in accordance with the terms hereof, the Exercise Quantity shall automatically be increased by such additional number of shares (rounded down to the nearest whole share) as is equal to (A) 3% of the amount of Aggregate Advances funded under the
Loan Agreement, if any, divided by (B) the Purchase Price, up to a maximum of 271,221 shares of Preferred Stock, including the Exercise Quantity. 
 In
addition to other terms which may be defined herein, the following terms, as used in this Warrant, shall have the following meanings: 
  

	 	(i)	“Aggregate Advances” means the aggregate original dollar amount of Advances made under the Loan Agreement, whether such Advances are outstanding or prepaid, at the time of any scheduled adjustment to
the Exercise Quantity. 

  
 1 

	 	(ii)	“Loan Agreement” means that certain Loan and Security Agreement No. 1321 dated September 15, 2008 between the Company and Lighthouse Capital Partners VI, L.P. 

Any term not defined herein shall have the meaning as set forth in the Loan Agreement. 

Until such time as this Warrant is exercised in full or expires, the Purchase Price and the securities issuable upon exercise of this Warrant are subject to
adjustment as hereinafter provided. The person or persons in whose name or names any certificate representing shares of Preferred Stock is issued hereunder shall be deemed to have become the holder of record of the shares represented thereby as at
the close of business on the date this Warrant is exercised with respect to such shares, whether or not the transfer books of the Company shall be closed. 

3. Payment of Purchase Price. The Purchase Price may be paid (i) in cash or by check, (ii) by the surrender by the
Holder to the Company of any promissory notes or other obligations issued by the Company, with all such notes and obligations so surrendered being credited against the Purchase Price in an amount equal to the principal amount thereof plus accrued
interest to the date of surrender, or (iii) by any combination of the foregoing. 
 4. Net Issue Election. The
Holder may elect to receive, without the payment by the Holder of any additional consideration, shares of Preferred Stock equal to the value of this Warrant or any portion hereof by the surrender of this Warrant or such portion to the Company, with
the net issue election notice annexed hereto duly executed, at the principal office of the Company. Thereupon, the Company shall issue to the Holder such number of fully paid and nonassessable shares of Preferred Stock as is computed using the
following formula: 
  
 

 
  

					
	 	        where: X =	  		the number of shares of Preferred Stock to be issued to the Holder pursuant to this Section 4.
		
	 	Y =	  		the number of shares of Preferred Stock covered by this Warrant in respect of which the net issue election is made pursuant to this Section 4.
		
	 	A =	  		the Fair Market Value (defined below) of one share of Preferred Stock, as determined at the time the net issue election is made pursuant to this Section 4.
		
	 	B =	  		the Purchase Price in effect under this Warrant at the time the net issue election is made pursuant to this Section 4.

 “Fair Market Value” of a share of Preferred Stock (or fully paid and nonassessable shares of
the Company’s common stock, (the “Common Stock”) if all of the Preferred Stock has been automatically converted into Common Stock) as of the date that the net issue election is made (the “Determination Date”)
shall mean: 
 (i) If the net issue election is made in connection with and contingent upon the closing of the sale of the
Company’s Common Stock to the public in a public offering pursuant to a Registration Statement under the 1933 Act (a “Public Offering”), and if the Company’s Registration Statement relating to such Public Offering
(“Registration Statement”) has been declared effective by the Securities and Exchange Commission, then the initial “Price to Public” specified in the final prospectus with respect to such offering multiplied by the number
of shares of Common Stock into which each share of Preferred Stock is then convertible. 

  
 2 

 (ii) If the net issue election is not made in connection with and contingent upon a Public
Offering, then as follows: 
 (a) If traded on a securities exchange or Nasdaq National Market, the fair market value of the Common Stock
shall be deemed to be the average of the closing or last reported sale prices of the Common Stock on such exchange or market over the five day period ending five trading days prior to the Determination Date, and the fair market value of the
Preferred Stock shall be deemed to be such fair market value of the Common Stock multiplied by the number of shares of Common Stock into which each share of Preferred Stock is then convertible; 

(b) If otherwise traded in an over-the-counter market, the fair market value of the Common Stock shall be deemed to be the average of the
closing ask prices of the Common Stock over the five day period ending five trading days prior to the Determination Date, and the fair market value of the Preferred Stock shall be deemed to be such fair market value of the Common Stock multiplied by
the number of shares of Common Stock into which each share of Preferred Stock is then convertible; and 
 (c) If there is no public market
for the Common Stock, then fair market value shall be determined in good faith by the Company’s Board of Directors. 
 5.
Partial Exercise. This Warrant may be exercised in part, and the Holder shall be entitled to receive a new warrant, which shall be dated as of the date of this Warrant, covering the number of shares in respect of which this Warrant shall not
have been exercised. 
 6. Fractional Shares. In no event shall any fractional share of Preferred Stock be issued upon
any exercise of this Warrant. If, upon exercise of this Warrant in its entirety, the Holder would, except as provided in this Section 6, be entitled to receive a fractional share of Preferred Stock, then the Company shall issue the next
lower number of full shares of Preferred Stock, and shall pay to the Holder a cash amount equal to the Fair Market Value (as of the date of exercise) of such fractional share of Preferred Stock. 

7. Expiration Date; Automatic Exercise. This Warrant shall expire (and shall be void thereafter) upon the earliest to occur of:
(a) the close of business on September 15, 2018, or (b) a Merger (as defined below) (each the “Expiration Date”). Notwithstanding the term of this Warrant fixed pursuant to this Section 7,
and provided Holder has received advance written notice of at least ten (10) days and has not earlier exercised this Warrant in full, and provided this Warrant has not been assumed by the successor entity (or parent thereof), upon the
consummation of a Merger (as defined below), this Warrant shall automatically be exercised in full pursuant to Section 4 hereof, without any action by Holder. “Merger” means: (i) a sale of all or
substantially all of the Company’s assets to an Unaffiliated Entity (as defined below), or (ii) the merger, consolidation or acquisition of the Company with, into or by an Unaffiliated Entity (other than a merger or consolidation for the
principle purpose of changing the domicile of the Company or a bona fide round of preferred stock equity financing), that results in the transfer of fifty percent (50%) or more of the outstanding voting power of the Company.
“Unaffiliated Entity” means any entity that is owned or controlled by parties who own less than twenty percent (20%) of the combined voting power of the voting securities of the Company immediately prior to such
merger, consolidation or acquisition. Notwithstanding the foregoing, in the event that any outstanding warrants to purchase equity securities of the Company are assumed by the successor entity of a Merger (or parent thereof), this Warrant shall also
be similarly assumed. The Company agrees to promptly give the Holder written notice of termination of any proposed Merger. Notwithstanding  

  
 3 

 
anything to the contrary in this Warrant, the Holder may rescind any exercise of this Warrant after being notified of termination of the proposed Merger if the exercise of this Warrant occurred
after the Company provided the Holder with advance written notice of the Merger, provided, however that such rescission right must be exercised within thirty (30) days of receipt of such written notice of termination of the proposed Merger. In
the event of such rescission, this Warrant will continue to be exercisable on the same terms and conditions. 
 8. Reserved Shares;
Valid Issuance. The Company covenants that it will at all times from and after the date hereof reserve and keep available such number of its authorized shares of Preferred Stock and Common Stock free from all preemptive or similar rights
therein, as will be sufficient to permit, respectively, the exercise of this Warrant in full and the conversion into shares of Common Stock (in accordance with the Articles, as defined below) of all shares of Preferred Stock receivable upon such
exercise. The Company further covenants that such shares as may be issued pursuant to such exercise and/or conversion will (in accordance with the Articles), upon issuance, be duly and validly issued, fully paid and nonassessable and free from all
taxes, liens and charges with respect to the issuance thereof. 
 9. Stock Splits and Dividends. If after the date
hereof the Company shall subdivide the Preferred Stock, by split-up or otherwise, or combine the Preferred Stock, or issue additional shares of Preferred Stock in payment of a stock dividend on the Preferred Stock, the number of shares of Preferred
Stock issuable on the exercise of this Warrant shall forthwith be proportionately increased in the case of a subdivision or stock dividend, or proportionately decreased in the case of a combination, and the Purchase Price shall forthwith be
proportionately decreased in the case of a subdivision or stock dividend, or proportionately increased in the case of a combination. 

10. Adjustments for Diluting Issuances. The other antidilution rights applicable to the Preferred Stock of the Company are set
forth in the Amended and Restated Articles of Incorporation, as amended from time to time (the “Articles”), a true and complete copy in its current form which is attached hereto as Exhibit
A. Such rights shall not be restated, amended or modified in any manner which affects the Holder differently than the holders of Preferred Stock without such Holder’s prior written consent. The Company shall promptly provide the
Holder hereof with any restatement, amendment or modification to the Articles promptly after the same has been made. 
 11.
Reclassifications. Subject to Section 7, if after the date hereof the Company shall enter into any Reorganization (as hereinafter defined), then, as a condition of such Reorganization, lawful provisions shall be made, and duly
executed documents evidencing the same from the Company or its successor shall be delivered to the Holder, so that the Holder shall thereafter have the right to purchase, at a total price not to exceed that payable upon the exercise of this Warrant
in full, the kind and amount of shares of stock and other securities and property receivable upon such Reorganization by a holder of the number of shares of Preferred Stock which might have been purchased by the Holder immediately prior to such
Reorganization, and in any such case appropriate provisions shall be made with respect to the rights and interest of the Holder to the end that the provisions hereof (including without limitation, provisions for the adjustment of the Purchase Price
and the number of shares issuable hereunder and the provisions relating to the net issue election) shall thereafter be applicable in relation to any shares of stock or other securities and property thereafter deliverable upon exercise hereof. For
the purposes of this Section 11, the term “Reorganization” shall include without limitation any reclassification, capital reorganization or change of the Preferred Stock (other than as a result of a
subdivision, combination or stock dividend provided for in Section 9 hereof). 
 12. Certificate of
Adjustment. Whenever the Purchase Price is adjusted, as herein provided, the Company shall promptly deliver to the Holder a certificate of the Company’s chief financial officer setting forth the Purchase Price after such adjustment and
setting forth a brief statement of the facts requiring such adjustment. 

  
 4 

 13. Notices of Record Date, Etc. In the event of: 

(a) any taking by the Company of a record of the holders of any class of securities for the purpose of determining the holders thereof who are
entitled to receive any dividend or other distribution, or any right to subscribe for, purchase, sell or otherwise acquire or dispose of any shares of stock of any class or any other securities or property, or to receive any other right; 

(b) any reclassification of the capital stock of the Company, capital reorganization of the Company, consolidation or merger involving the
Company, or sale or conveyance of all or substantially all of its assets; or 
 (c) any voluntary or involuntary dissolution, liquidation or
winding-up of the Company; 
 then in each such event the Company will provide or cause to be provided to the Holder a written notice thereof. Such notice
shall be provided at least ten (10) business days prior to the date specified in such notice on which any such action is to be taken. 

14. Representations, Warranties and Covenants. This Warrant is issued and delivered by the Company and accepted by each Holder on
the basis of the following representations, warranties and covenants made by the Company: 
 (a) The Company has all necessary
authority to issue, execute and deliver this Warrant and to perform its obligations hereunder. This Warrant has been duly authorized issued, executed and delivered by the Company and is the valid and binding obligation of the Company, enforceable in
accordance with its terms. 
 (b) The shares of Preferred Stock issuable upon the exercise of this Warrant have been duly authorized and
reserved for issuance by the Company and, when issued in accordance with the terms hereof, will be validly issued, fully paid and nonassessable. 

(c) The issuance, execution and delivery of this Warrant do not, and the issuance of the shares of Preferred Stock upon the exercise of this
Warrant in accordance with the terms hereof will not, (i) violate or contravene the Company’s Articles or by-laws, or any law, statute, regulation, rule, judgment or order applicable to the Company, (ii) violate, contravene or result
in a breach or default under any contract, agreement or instrument to which the Company is a party or by which the Company or any of its assets are bound or (iii) require the consent or approval of or the filing of any notice or registration
with any person or entity, except for filings required under California securities law. 
 (d) As long as this Warrant is, or any shares of
Preferred Stock issued upon exercise of this Warrant or any shares of Common Stock issued upon conversion of such shares of Preferred Stock are, issued and outstanding, the Company will provide to the Holder the financial and other information
described in Section 3.1 of that certain Amended and Restated Investor Rights Agreement between the Company and the signatories thereto, dated as of August 9, 2007, as amended from time to time (the “Rights Agreement”) regardless
of any minimum share ownership thresholds set forth in Section 3.1 of the then-current Rights Agreement (or the successor provision, if the section reference has been changed). 

  
 5 

 (e) As of the date hereof, the authorized capital stock of the Company consists of
(i) 33,000,000 shares of Common Stock, of which 11,166,001 shares are issued and outstanding and 271,221 shares are reserved for issuance upon the exercise of this Warrant with respect to Common Stock and the conversion of the Preferred Stock
into Common Stock if this Warrant is exercised with respect to Preferred Stock, and (ii) 7,496,660 shares of Series A Preferred Stock, of which 7,161,530 are issued and outstanding shares, and (iii) 9,271,221 shares of Series B Preferred
Stock, of which 8,856,408 are issued and outstanding shares. Attached hereto as Exhibit B is a capitalization table summarizing the capitalization of the Company. At the request of Holder, not more than once per calendar
quarter, the Company will provide Holder with a current capitalization table indicating changes, if any, to the number of outstanding shares of common stock and preferred stock. 

15. Registration Rights. The Company and the Holder have entered into an Amendment to the Amended and Restated Investor Rights
Agreement dated as of the date of this Warrant in the form attached hereto as Exhibit C. 
 16.
Amendment. The terms of this Warrant may be amended, modified or waived only with the written consent of the Holder and the Company. 

17. Representations and Covenants of the Holder. This Warrant has been entered into by the Company in reliance upon the following
representations and covenants of the Holder, which by its execution hereof the Holder hereby confirms: 
 (a) Investment
Purpose. The right to acquire Preferred Stock or the Preferred Stock issuable upon exercise of the Holder’s rights contained herein will be acquired for investment and not with a view to the sale or distribution of any part thereof, and the
Holder has no present intention of selling or engaging in any public distribution of the same except pursuant to a registration or exemption. 

(b) Accredited Investor. Holder is an “accredited investor” within the meaning of the Securities and Exchange Rule 501 of
Regulation D, as presently in effect. 
 (c) Private Issue. The Holder understands (i) that the Preferred Stock issuable upon
exercise of the Holder’s rights contained herein is not registered under the 1933 Act or qualified under applicable state securities laws on the ground that the issuance contemplated by this Warrant will be exempt from the registration and
qualifications requirements thereof, and (ii) that the Company’s reliance on such exemption is predicated on the representations set forth in this Section 17. 

(d) Financial Risk. The Holder has such knowledge and experience in financial and business matters as to be capable of evaluating the
merits and risks of its investment and has the ability to bear the economic risks of its investment. 
 18. Notices, Transfers, Etc.

 (a) Any notice or written communication required or permitted to be given to the Holder may be given by certified mail or delivered to
the Holder at the address most recently provided by the Holder to the Company. 
 (b) Subject to compliance with applicable federal and state
securities laws and Section 2.1 of the Rights Agreement, as the same may be amended from time to time, this Warrant may be transferred by the Holder with respect to any or all of the shares purchasable hereunder. Upon surrender of this Warrant
to the Company, together with the assignment notice annexed hereto duly executed, for transfer 

  
 6 

 
of this Warrant as an entirety by the Holder, the Company shall issue a new warrant of the same denomination to the assignee. Upon surrender of this Warrant to the Company, together with the
assignment hereof properly endorsed, by the Holder for transfer with respect to a portion of the shares of Preferred Stock purchasable hereunder, the Company shall issue a new warrant to the assignee, in such denomination as shall be requested by
the Holder hereof, and shall issue to such Holder a new warrant covering the number of shares in respect of which this Warrant shall not have been transferred. 

(c) In case this Warrant shall be mutilated, lost, stolen or destroyed, the Company shall issue a new warrant of like tenor and denomination
and deliver the same (i) in exchange and substitution for and upon surrender and cancellation of any mutilated Warrant, or (ii) in lieu of any Warrant lost, stolen or destroyed, upon receipt of an affidavit of the Holder or other evidence
reasonably satisfactory to the Company of the loss, theft or destruction of such Warrant. 
 19. No Impairment. The Company
will not, by amendment of its Articles or through any reclassification, capital reorganization, consolidation, merger, sale or conveyance of assets, dissolution, liquidation, issue or sale of securities or any other voluntary action, avoid or seek
to avoid the observance of performance of any of the terms of this Warrant, but will at all times in good faith assist in the carrying out of all such terms and in the taking of all such action as may be necessary or appropriate in order to protect
the rights of the Holder. 
 20. Governing Law. The provisions and terms of this Warrant shall be governed by and
construed in accordance with the internal laws of the State of California without giving effect to its principles regarding conflicts of laws. 

21. Successors and Assigns. This Warrant shall be binding upon the Company’s successors and assigns and shall inure to the
benefit of the Holder’s successors, legal representatives and permitted assigns. 
 22. Business Days. If the last
or appointed day for the taking of any action required or the expiration of any rights granted herein shall be a Saturday or Sunday or a legal holiday in California, then such action may be taken or right may be exercised on the next succeeding day
which is not a Saturday or Sunday or such a legal holiday. 
 23. Qualifying Public Offering. If the Company shall
effect a firm commitment underwritten public offering of shares of Common Stock which results in the conversion of the Preferred Stock into Common Stock pursuant to the Company’s Articles in effect immediately prior to such offering, then,
effective upon such conversion, this Warrant shall change from the right to purchase shares of Preferred Stock to the right to purchase shares of Common Stock, and the Holder shall thereupon have the right to purchase, at a total price equal to that
payable upon the exercise of this Warrant in full, the number of shares of Common Stock which would have been receivable by the Holder upon the exercise of this Warrant for shares of Preferred Stock immediately prior to such conversion of such
shares of Preferred Stock into shares of Common Stock, and in such event appropriate provisions shall be made with respect to the rights and interest of the Holder to the end that the provisions hereof (including, without limitation, the provisions
for the adjustment of the Purchase Price and of the number of shares purchasable upon exercise of this Warrant and the provisions relating to the net issue election) shall thereafter be applicable to any shares of Common Stock deliverable upon the
exercise hereof. 
 24. Value. The Company and the Holder agree that the value of this Warrant on the date of grant is $100.

  
 7 

 25. Market Stand-Off. The Holder agrees and acknowledges that this Warrant and the
shares of Preferred Stock (or any shares of Common Stock issued upon conversion of the Preferred Stock) issuable upon exercise of this Warrant are subject to the requirements and terms regarding Market Stand-Off contained in the Company’s
then-current Rights Agreement. 
  
  

			
	INVUITY, INC.
		
	By:		 /s/ Jonathan Gasson

	Name:		Jonathan Gasson
	Title:		President

  
 8

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