Document:

Exhibit 10.58

  

INDEMNIFICATION AGREEMENT

 

THIS INDEMNIFICATION AGREEMENT (this “Agreement”)
is made and entered into this _5th day of January, 2018, by and between Actinium Pharmaceuticals, Inc., a Delaware corporation
(the “Corporation”), and Dale L. Ludwig (“Indemnitee”).

 

RECITALS

 

WHEREAS, the Corporation,
which is organized under the General Corporation Law of the State of Delaware (as amended, the “DGCL”), wishes
to enter into this Agreement to set forth certain rights and obligations of the Indemnitee and the Corporation with respect to
the Indemnitee’s service as an officer of the Corporation;

 

WHEREAS, it is essential
to the Corporation that it be able to retain and attract as directors and officers the most capable persons available;

 

WHEREAS, increased
corporate litigation has subjected directors and officers to litigation risks and expenses, and the limitations on the availability
of directors and officers liability insurance have made it difficult for the Corporation to attract and retain such persons;

 

WHEREAS, the Board
of Directors of the Corporation (the “Board”) has determined that the difficulty in attracting and retaining
such persons is detrimental to the best interests of the Corporation’s stockholders and that the Corporation should contractually
obligate itself to indemnify, and to advance expenses on behalf of, such persons to the fullest extent permitted by applicable
law so that they will serve the Corporation free from undue concern that they will not be so indemnified;

 

WHEREAS, Indemnitee
performs a valuable service to the Corporation in Indemnitee’s capacity as an officer of the Corporation;

 

WHEREAS, the Corporation’s
Amended and Restated Bylaws (the “Bylaws”) include provisions providing for the indemnification of the directors
and officers of the Corporation, including persons serving at the request of the Corporation in such capacities with other corporations
or enterprises, as authorized by the DGCL;

 

WHEREAS, the Corporation’s
Certificate of Incorporation (the “Charter”), the Bylaws and the DGCL, by their nonexclusive nature, permit
contracts between the Corporation and its directors and officers with respect to indemnification of such persons;

  

WHEREAS, in recognition of Indemnitee’s
need for (a) substantial protection against personal liability as a condition to Indemnitee’s service to the Corporation
in Indemnitee’s capacity as an officer of the Corporation in addition to Indemnitee’s reliance on the Bylaws, which
Indemnitee believes is inadequate in the present circumstances, and (b) specific contractual assurance of Indemnitee’s rights
to full indemnification against risks and expenses (regardless of, among other things, any amendment to or revocation of the Charter
and/or the Bylaws, any change in the composition of the Corporation’s Board, or a change in control of the Corporation);

 

     

     

    

  

WHEREAS, the Corporation
intends that this Agreement provide Indemnitee with greater protection than that which is provided by the Bylaws; and

 

WHEREAS, in order
to induce Indemnitee to serve as an officer of the Corporation, the Corporation has determined and agreed to enter into this Agreement
with Indemnitee.

 

NOW, THEREFORE, in
consideration of Indemnitee’s service as an officer of the Corporation following the date hereof, and for other good and
valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Corporation and Indemnitee hereby agree
as follows:

 

1.            
Indemnity of Indemnitee. The Corporation agrees to hold harmless and indemnify Indemnitee to the fullest extent authorized
or permitted by law, the provisions of the Charter, and the Bylaws, as the same may be amended from time to time (but, only to
the extent that such amendment permits the Corporation to provide broader indemnification rights than such law, the Charter, or
the Bylaws permitted prior to adoption of such amendment). For purposes of this Agreement, the meaning of the phrase “to
the fullest extent authorized or permitted by law” shall include, but not be limited to: (i) to the fullest extent authorized
or permitted by the provision of the DGCL that authorizes or contemplates additional indemnification by agreement, or the corresponding
provision of any amendment to or replacement of the DGCL or such provision thereof; and (ii) to the fullest extent authorized or
permitted by any amendments to or replacements of the DGCL adopted after the date of this Agreement that increase the extent to
which a corporation may indemnify its directors and officers.

 

2.            
Additional Indemnity. In addition to and not in limitation of the indemnification otherwise provided for herein, and subject
only to the exclusions set forth in Section 3 hereof, the Corporation further agrees to hold harmless and indemnify Indemnitee:

 

(a)            
against any and all (i) expenses (including attorneys’ fees), retainers, court costs, transcript costs, fees of experts,
witness fees, travel expenses, duplicating costs, printing and binding costs, telephone charges, postage, delivery service fees
and all other disbursements or expenses of the types customarily incurred in connection with prosecuting, defending, preparing
to prosecute or defend, investigating, participating, or being or preparing to be a witness in any threatened, pending or completed
action, suit, arbitration, alternate dispute resolution mechanism, investigation, inquiry, administrative hearing or any other
actual, threatened or completed proceeding, including any appeal thereof or related thereto (each, a “Proceeding”),
or responding to, or objecting to, a request to provide discovery in any Proceeding, (ii) damages, judgments, fines and amounts
paid in settlement and any other amounts that Indemnitee becomes legally obligated to pay (including any federal, state or local
taxes imposed on Indemnitee as a result of receipt of reimbursements or advances of expenses under this Agreement) and (iii) the
premium, security for, and other costs relating to any costs bond, supersedes bond, or other appeal bond or its equivalent, whether
civil, criminal, arbitrational, administrative or investigative with respect to any Proceeding (items under clauses, (i), (ii)
and (iii), collectively, the “Expenses”) actually and reasonably incurred by Indemnitee, or on Indemnitee’s
behalf, because of any claim or claims made against or by him in connection with any Proceeding, whether formal or informal (including
an action by or in the right of the Corporation), to which Indemnitee is, was or at any time becomes a party or a witness, or is
threatened to be made a party to, a participant in or a witness with respect to, by reason of the fact that Indemnitee is, was
or at any time becomes a director or officer of the Corporation, or is or was serving or at any time serves at the request of the
Corporation as a director or officer of another corporation, partnership, joint venture, trust or other enterprise (“Corporate
Status”);

 

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(b)            against any and all Expenses actually and reasonably incurred by Indemnitee, or on Indemnitee’s behalf, if Indemnitee is,
or is threatened to be made, a party to or a participant in any Proceeding by or in the right of the Corporation to procure a judgment
in its favor;

 

(c)            against any and all Expenses actually and reasonably incurred by Indemnitee, or on Indemnitee’s behalf, if Indemnitee is,
by reason of his or her Corporate Status, a witness in any Proceeding to which Indemnitee is not a party and is not threatened
to be made a party; and

 

(d)            otherwise to the fullest extent as may be provided to Indemnitee by the Corporation under the non-exclusivity provisions of the
DGCL, the Charter and the Bylaws.

 

3.            Limitations
on Additional Indemnity. No indemnity pursuant to Section 2 hereof shall be paid by the Corporation:

 

(a)            on account of any claim or Proceeding against Indemnitee for an accounting of profits made from the purchase or sale by Indemnitee
of securities of the Corporation pursuant to the provisions of Section 16(b) of the Securities Exchange Act of 1934, as heretofore
or hereafter amended (the “Exchange Act”), or similar provisions of any federal, state or local law if the final,
non-appealable judgment of a court of competent jurisdiction finds Indemnitee to be liable for disgorgement under Section 16(b)
of the Exchange Act;

 

(b)            on account of Indemnitee’s conduct that is established by a final, non-appealable judgment of a court of competent jurisdiction
as knowingly fraudulent or deliberately dishonest or that constituted willful misconduct;

 

(c)            for which payment is actually made to Indemnitee under (i) a valid and collectible insurance policy, including under any policy
of insurance purchased and maintained on Indemnitee’s behalf by the Corporation or (ii) under a valid and enforceable indemnity
clause, bylaw, or agreement, including, but not limited to, an indemnity clause, bylaw, or agreement relating to another corporation,
partnership, joint venture, trust, or other enterprise for which Indemnitee is or was serving as a director or officer at the request
of the Corporation; provided, that indemnity pursuant to Section 2 hereof shall be paid by the Corporation in respect
of any excess beyond payment actually received by Indemnitee under such insurance policy, clause, bylaw or agreement;

 

(d)            
if and to the extent indemnification is contrary to law, either as a matter of public policy, or under the provisions of the Federal
Securities Act of 1933, as amended, the Securities Exchange Act of 1934, as amended, the DGCL, or any other applicable law; or

 

(e)            in connection with any Proceeding (or part thereof) initiated by Indemnitee, against the Corporation or its directors, officers,
employees or other agents, unless (i) such indemnification is expressly required to be made by law, (ii) the Corporation has joined
in the Proceeding (or relevant part thereof), (iii) the Board has consented to the initiation of such Proceeding, (iv) such indemnification
is provided by the Corporation, in its sole discretion, pursuant to the powers vested in the Corporation under the DGCL, or (v)
the Proceeding (or relevant part thereof) is initiated pursuant to Section 12 hereof.

 

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4.            
Continuation of Indemnity. All agreements and obligations of the Corporation contained herein shall continue during the
period Indemnitee is a director or officer of the Corporation (or is or was serving at the request of the Corporation as a director
or officer of another corporation, partnership, joint venture, trust or other enterprise) and shall continue thereafter so long
as Indemnitee shall be subject to any possible claim or threatened, pending or completed Proceeding, whether civil, criminal, arbitrational,
administrative or investigative, including any appeal thereof or relating thereto, in respect of which Indemnitee is granted rights
of indemnification or advancement of Expenses hereunder, in each case, by reason of the fact of the Indemnitee’s Corporate
Status.

 

5.            
Partial Indemnification. Indemnitee shall be entitled under this Agreement to indemnification by the Corporation for a portion
of the Expenses, judgments, fines and amounts paid in settlement and any other amounts that Indemnitee becomes legally obligated
to pay in connection with any Proceeding referred to in Section 2 hereof even if not entitled hereunder to indemnification
for the total amount thereof, and the Corporation shall indemnify Indemnitee for the portion thereof to which Indemnitee is entitled.

 

6.            
Notification and Defense of Claim. To obtain indemnification under this Agreement, Indemnitee shall submit to the Corporation
a written request therefor. As soon as practicable, and in any event, not later than thirty (30) days after Indemnitee becomes
aware, by written or other overt communication, of any pending or threatened litigation, claim or assessment, Indemnitee will,
if a claim for indemnification in respect thereof is to be made against the Corporation under this Agreement, notify the Corporation
of such pending or threatened litigation, claim or assessment; but the omission so to notify the Corporation will not relieve the
Corporation from any liability which it may have to Indemnitee otherwise under this Agreement, and any delay in so notifying the
Corporation shall not constitute a waiver by Indemnitee of any of Indemnitee’s rights under this Agreement. With respect
to any such pending or threatened litigation, claim or assessment as to which Indemnitee notifies the Corporation of the commencement
thereof:

 

(a)            
the Corporation will be entitled to participate therein at its own expense;

 

(b)            except as otherwise provided below, the Corporation may, at its option and jointly with any other indemnifying party similarly
notified and electing to assume such defense, assume the defense thereof, with counsel reasonably satisfactory to Indemnitee. After
notice from the Corporation to Indemnitee of its election to assume the defense thereof, the Corporation will not be liable to
Indemnitee under this Agreement for any legal or other expenses subsequently incurred by Indemnitee in connection with the defense
thereof except for reasonable costs of investigation or otherwise as provided below. Indemnitee shall have the right to employ
separate counsel in such Proceeding but the fees and expenses of such counsel incurred after notice from the Corporation of its
assumption of the defense thereof shall be at the expense of Indemnitee unless (i) the employment of counsel by Indemnitee has
been authorized by the Corporation, (ii) Indemnitee shall have reasonably concluded, and so notified the Corporation, that there
may be a conflict of interest between the Corporation and Indemnitee in the conduct of the defense of such action, or (iii) the
Corporation shall not in fact have employed counsel to assume the defense of Indemnitee in connection with such action; in any
of such cases the fees and expenses of Indemnitee’s separate counsel shall be at the expense of the Corporation. The Corporation
shall not be entitled to assume the defense of any Proceeding brought by or on behalf of the Corporation or as to which Indemnitee
shall have made the conclusion provided for in clause (ii) above; and

 

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(c)            the Corporation shall not be liable to indemnify Indemnitee under this Agreement for any amounts paid in settlement of any action
or claim effected without the Corporation’s written consent, which consent shall not be unreasonably withheld, conditioned
or delayed. The Corporation shall not enter into any settlement in connection with a Proceeding in any manner which would impose
any Expenses, penalties (whether civil or criminal) or limitations on Indemnitee without Indemnitee’s written consent, which
may be given or withheld in Indemnitee’s sole and reasonable discretion.

 

7.             Expenses.
The Corporation shall advance, to the extent not prohibited by law, all Expenses actually and reasonably incurred by Indemnitee
in connection with any Proceeding promptly following request therefor, but in any event no later than twenty (20) days after the
receipt by the Corporation of a written statement or statements requesting such advances (which shall include invoices received
by Indemnitee in connection with such Expenses but, in the case of invoices in connection with legal services, any references to
legal work performed or to expenditure made that would cause Indemnitee to waive any privilege accorded by applicable law shall
not be included with the invoice) from time to time, whether prior to or after the final disposition of any Proceeding. The right
to advancement described in this Section 7 is vested. Advances shall be unsecured and interest free. Advances shall be made
without regard to Indemnitee’s ability to repay the expenses and without regard to Indemnitee’s ultimate entitlement
to indemnification under the other provisions of this Agreement. The execution and delivery to the Corporation of this Agreement
shall constitute an undertaking by Indemnitee to the fullest extent required by law to repay all advances if and to the extent
that it is ultimately determined by a court of competent jurisdiction in a final, non-appealable judgment that Indemnitee is not
entitled to be indemnified by the Corporation, and Indemnitee shall qualify for advances immediately upon such execution and delivery.
The right to advances under this Section 7 shall in all events continue until final disposition of any Proceeding, including
any appeal therein.

 

8.             Contribution.

 

(a)             Whether or not the indemnification provided in Section 2 is available, in respect of any Proceeding in which the Corporation
is jointly liable with Indemnitee (or would be if joined in such Proceeding), the Corporation shall pay, in the first instance,
the entire amount of any judgment or settlement of such Proceeding without requiring Indemnitee to contribute to such payment and
the Corporation hereby waives and relinquishes any right of contribution it may have against Indemnitee. The Corporation shall
not enter into any settlement of any Proceeding in which the Corporation is jointly liable with Indemnitee (or would be if joined
in such Proceeding) unless such settlement provides for a full and final release of all claims asserted against Indemnitee.

 

(b)             Without diminishing or impairing the obligations of the Corporation set forth in Section 8(a), if, for any reason, Indemnitee
shall elect or be required to pay all or any portion of any judgment or settlement in any threatened, pending or completed Proceeding
in which the Corporation is jointly liable with Indemnitee (or would be if joined in such Proceeding), the Corporation shall contribute
to the amount of Expenses, judgments, fines and amounts paid in settlement actually and reasonably incurred and paid or payable
by Indemnitee in proportion to the relative benefits received by the Corporation and all officers, directors or employees of the
Corporation, other than Indemnitee, who are jointly liable with Indemnitee (or would be if joined in such Proceeding), on the one
hand, and Indemnitee, on the other hand, from the transaction from which such Proceeding arose; provided, however,
that the proportion determined on the basis of relative benefit may, to the extent necessary to conform to law, be further adjusted
by reference to the relative fault of the Corporation and all officers, directors or employees of the Corporation other than Indemnitee
who are jointly liable with Indemnitee (or would be if joined in such Proceeding), on the one hand, and Indemnitee, on the other
hand, in connection with the events that resulted in such expenses, judgments, fines or settlement amounts, as well as any other
equitable considerations which the law may require to be considered. The relative fault of the Corporation and all officers, directors
or employees of the Corporation, other than Indemnitee, who are jointly liable with Indemnitee (or would be if joined in such Proceeding),
on the one hand, and Indemnitee, on the other hand, shall be determined by reference to, among other things, the degree to which
their actions were motivated by intent to gain personal profit or advantage, the degree to which their liability is primary or
secondary and the degree to which their conduct is active or passive.

 

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(c)             The Corporation hereby agrees to fully indemnify and hold Indemnitee harmless from any claims of contribution which may be brought
by officers, directors or employees of the Corporation, other than Indemnitee, who may be jointly liable with Indemnitee.

  

(d)            To the fullest
extent permissible under applicable law, if the indemnification provided for in this Agreement is unavailable to Indemnitee for
any reason whatsoever, the Corporation, in lieu of indemnifying Indemnitee, shall contribute to the amount actually and reasonably
incurred by Indemnitee, whether for judgments, fines, penalties, excise taxes, amounts paid or to be paid in settlement and/or
for Expenses, in connection with any claim relating to an indemnifiable event under this Agreement, in such proportion as is deemed
fair and reasonable in light of all of the circumstances of such Proceeding in order to reflect (i) the relative benefits received
by the Corporation and Indemnitee as a result of the event(s) and/or transaction(s) giving cause to such Proceeding; and/or
(ii) the relative fault of the Corporation (and its directors, officers, employees and agents) and Indemnitee in connection with
such event(s) and/or transaction(s).

 

9.              Presumptions
and Effect of Certain Proceedings.

 

(a)            
In making a determination with respect to Indemnitee’s entitlement to indemnification hereunder, the person, persons or entity
making such determination shall, to the fullest extent not prohibited by law, presume that Indemnitee is entitled to indemnification
under this Agreement if Indemnitee has submitted a request for indemnification in accordance with Section 6 hereof. If the
Corporation contests any claim or assertion that Indemnitee is entitled to indemnification hereunder, the Corporation shall, to
the fullest extent not prohibited by law, have the burden of proof to overcome such presumption in connection with the making by
such person, persons, or entity of any determination with respect to Indemnitee’s entitlement to indemnification.

 

(b)            
Without limiting the foregoing, if any Proceeding is disposed of on the merits or otherwise (including a disposition without prejudice),
without (i) the final disposition being adverse to Indemnitee, (ii) a final adjudication by a court of competent jurisdiction that
Indemnitee was liable to the Corporation, (iii) a plea of guilty (iv) a final adjudication by a court of competent jurisdiction
that Indemnitee did not act in good faith, and in a manner Indemnitee reasonably believed to be in or not opposed to the best interests
of the Corporation, or (v) with respect to any criminal proceeding, a final adjudication by a court of competent jurisdiction that
Indemnitee had reasonable cause to believe Indemnitee’s conduct was unlawful, Indemnitee shall be considered for the purposes
hereof to have been wholly successful with respect thereto.

 

(c)            
The termination of any Proceeding or of any claim, issue or matter therein, by judgment, order, settlement or conviction, or upon
a plea of nolo contendere or its equivalent, shall not (except as otherwise expressly provided in this Agreement) of itself adversely
affect the right of Indemnitee to indemnification or create a presumption that Indemnitee did not act in good faith and in a manner
which he or she reasonably believed to be in or not opposed to the best interests of the Corporation or, with respect to any criminal
Proceeding, that Indemnitee had reasonable cause to believe that such Indemnitee’s conduct was unlawful.

 

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(d)            
For purposes of any determination of good faith, Indemnitee shall be deemed to have acted in good faith to the extent Indemnitee
relied in good faith on (i) the records or books of account of the Corporation, including financial statements , (ii) information
supplied to Indemnitee by the officers of the Corporation in the course of their duties, (iii) the advice of legal counsel for
the Corporation or its Board or counsel selected by any committee of the Board or (iv ) information or records given or reports
made to the Corporation by an independent certified public accountant, an appraiser, investment banker or other expert selected
with reasonable care by the Corporation or its Board or any committee of the Board.

 

10.       
   Information Sharing. To the extent that the Corporation receives a request or requests from a
governmental third party or other licensing or regulating organization (the “Requesting Agency”), whether
formal or informal, to produce documentation or other information concerning an investigation, whether formal or informal,
being conducted by the Requesting Agency, and such investigation is reasonably likely to include review of any actions or
failures to act by Indemnitee, the Corporation shall promptly give notice to Indemnitee of said request or requests and any
subsequent request. In addition, the Corporation shall provide Indemnitee with a copy of any and all information or
documentation that the Corporation shall provide to the Requesting Agency.

 

11.           
No Imputation. The knowledge and/or actions, or failure to act, of any director, officer, agent or employee of the Corporation
or the Corporation itself shall not be imputed to Indemnitee for purposes of determining any rights under this Agreement.

 

12.           
Enforcement.

 

(a)             Any
right to indemnification or advances granted by this Agreement to Indemnitee shall be enforceable by or on behalf of Indemnitee
in any court of competent jurisdiction if (i) the claim for indemnification or advances is denied, in whole or in part, (ii) no
disposition of such claim is made within ninety (90) days of request therefor; (iii) advancement of Expenses is not timely
made pursuant to Section 7, (iv) payment of indemnification pursuant to this Agreement is not made within ten (10) days
after a determination has been made that Indemnitee is entitled to indemnification, or (v) the Corporation or any other person
or entity takes or threatens to take any action to declare this Agreement void or unenforceable, or institutes any litigation or
other action or proceeding designed to deny, or to recover from, Indemnitee the benefits provided or intended to be provided to
Indemnitee hereunder, Indemnitee shall be entitled to an adjudication by the Delaware Court of Chancery of Indemnitee’s entitlement
to such indemnification or advancement of Expenses, and the Corporation shall not oppose Indemnitee’s right to seek any such
adjudication in accordance with this Agreement. Indemnitee, in such enforcement action, if successful in whole or in part, shall
be entitled to be paid also the Expenses of prosecuting Indemnitee’s claim. It shall be a defense to any action for which
a claim for indemnification is made under Section 2 hereof (other than an action brought to enforce a claim for advance
or reimbursement of Expenses under this Agreement, provided that the required undertaking has been tendered to the Corporation)
that Indemnitee is not entitled to indemnification because of the limitations set forth in Section 3 hereof. Neither the
failure of the Corporation (including the Board, any committee of the Board, or the Corporation’s its stockholders, or any
subgroup of such directors or stockholders) to have made a determination prior to the commencement of such enforcement action that
indemnification of Indemnitee is proper in the circumstances, nor an actual determination by the Corporation (including the Board,
any committee of the Board, or the Corporation’s stockholders, or any subgroup of such directors or stockholders) that such
indemnification is improper shall be a defense to the action or create a presumption that Indemnitee is not entitled to indemnification
under this Agreement or otherwise.

 

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(b)             To
the fullest extend not prohibited by law, the Corporation shall be precluded from asserting in any judicial proceeding commenced
pursuant to this Section 12 that the procedures and presumptions of this Agreement are not valid, binding and enforceable
and shall stipulate in any such court that the Corporation is bound by all the provisions of this Agreement. If a determination
shall have been made pursuant to this Agreement that Indemnitee is entitled to indemnification, the Corporation shall be bound
by such determination in any Proceeding commenced pursuant to this Section 12, absent (i) a misstatement by Indemnitee of
a material fact, or an omission of a material fact necessary to make Indemnitee’s statements not materially misleading, in
connection with the request for indemnification, or (ii) a prohibition of such indemnification under applicable law.

 

13.            
Subrogation. In the event of payment under this Agreement, the Corporation shall be subrogated to the extent of such payment
to all of the rights of recovery of Indemnitee, who shall execute all documents required and shall do all acts that may be necessary
to secure such rights and to enable the Corporation effectively to bring suit to enforce such rights.

 

14.            
Non-Exclusivity of Rights. The rights conferred on Indemnitee by this Agreement shall not be exclusive of any other right
which Indemnitee may have or hereafter acquire under any statute, provision of the Charter or Bylaws, agreement, vote of stockholders
or directors, or otherwise, both as to action in Indemnitee’s official capacity and as to action in another capacity while
holding office. To the extent that a change in applicable law, whether by statute or judicial decision, permits greater indemnification
or advancement of Expenses than would be afforded currently under the Charter or Bylaws and this Agreement, it is the intent of
the parties hereto that Indemnitee shall enjoy by this Agreement the greater benefits so afforded by such change, subject to the
restrictions expressly set forth herein or therein. Except as expressly set forth herein, no right or remedy herein conferred is
intended to be exclusive of any other right or remedy, and every other right and remedy shall be cumulative and in addition to
every other right and remedy given hereunder or now or hereafter existing at law or in equity or otherwise. Except as expressly
set forth herein, the assertion or employment of any right or remedy hereunder, or otherwise, shall not prevent the concurrent
assertion or employment of any other right or remedy.

 

15.            
Insurance. To the extent that the Corporation maintains an insurance policy or policies providing liability insurance for
directors, trustees, general partners, managing members, officers, employees, agents or fiduciaries of the Corporation, Indemnitee
shall be covered by such policy or policies (including with respect to prior service) to the same extent as the most favorably-insured
persons under such policy or policies in a comparable position.

 

16.            
Enforcement; Survival of Rights.

 

(a)            
The Corporation expressly confirms and agrees that the Corporation has entered into this Agreement and assumed the obligations
imposed on it hereby in order to induce Indemnitee to serve as a director of the Corporation, and the Corporation acknowledges
that Indemnitee is relying upon this Agreement in serving the Corporation in such capacity.

 

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(b)            
The rights conferred on Indemnitee by this Agreement shall continue after Indemnitee has ceased to be a director or officer of
the Corporation or to serve at the request of the Corporation as a director or officer agent of another corporation, partnership,
joint venture, trust or other enterprise, and shall inure to the benefit of Indemnitee’s heirs, executors and administrators.

 

(c)            
The Corporation shall require any successor (whether direct or indirect, by purchase, merger, consolidation or otherwise) to all
or substantially all of the business or assets of the Corporation, expressly to assume and agree to perform this Agreement in the
same manner and to the same extent that the Corporation would be required to perform if no such succession had taken place.

 

(d)            
The Corporation and Indemnitee agree herein that a monetary remedy for breach of this Agreement, at some later date, may be inadequate,
impracticable and difficult of proof, and further agree that such breach may cause Indemnitee and the Corporation irreparable harm.
Accordingly, the parties hereto agree that each of the Corporation and the Indemnitee may enforce this Agreement by seeking injunctive
relief and/or specific performance hereof, without any necessity of showing actual damage or irreparable harm and that by seeking
injunctive relief and/or specific performance, they shall not be precluded from seeking or obtaining any other relief to which
they may be entitled. The Corporation and Indemnitee further agree that they shall be entitled to such specific performance and
injunctive relief, including temporary restraining orders, preliminary injunctions and permanent injunctions, without the necessity
of posting bonds or other undertaking in connection therewith. The Corporation and Indemnitee acknowledge that in the absence of
a waiver, a bond or undertaking may be required by the Delaware Court of Chancery, and they hereby waive any such requirement of
such a bond or undertaking.

  

17.            
No Conflicts.To the extent that any provision of this Agreement conflicts with the Charter, the Bylaws, or applicable
law, the Charter, the Bylaws, or such applicable law (as applicable) shall govern.

  

18.            
Separability. Each of the provisions of this Agreement is a separate and distinct agreement and independent of the others,
so that if any provision hereof shall be held to be invalid, illegal or unenforceable for any reason, (i) such invalidity, illegality
or unenforceability shall not affect the validity, legality or enforceability of the remaining provisions of this Agreement (including
without limitation, each portion of any Section of this Agreement containing any such provision held to be invalid, illegal or
unenforceable, that is not itself invalid, illegal or unenforceable) and such other provisions shall remain enforceable to the
fullest extent permitted by law; (ii) such provision or provisions shall be deemed reformed to the extent necessary to conform
to applicable law and to give the maximum effect to the intent of the parties hereto; and (iii) to the fullest extent possible,
the provisions of this Agreement (including, without limitation, each portion of any section of this Agreement containing any such
provision held to be invalid, illegal or unenforceable, that is not itself invalid, illegal or unenforceable) shall be construed
so as to give effect to the intent manifested thereby. Furthermore, if this Agreement shall be invalidated in its entirety on any
ground, then the Corporation shall nevertheless indemnify Indemnitee to the fullest extent provided by the Charter (if applicable),
the Bylaws, the DGCL or any other applicable law.

 

19.            
Governing Law. This Agreement shall be governed by, and construed and enforced in accordance with, the laws of the State
of Delaware, without regard to its principles of conflicts of laws. The Corporation and Indemnitee hereby irrevocably and unconditionally
(i) agree that any action or proceeding arising out of or in connection with this Agreement may be brought in the Delaware Court
of Chancery, (ii) consent to submit to the jurisdiction of the Delaware Court of Chancery for purposes of any action or proceeding
arising out of or in connection with this Agreement, (iii) waive any objection to the laying of venue of any such action or proceeding
in the Delaware Court of Chancery, and (iv) waive, and agree not to plead or to make, any claim that any such action or proceeding
brought in the Delaware Court of Chancery has been brought in an improper or inconvenient forum.

 

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20.            
Amendment and Termination. No amendment, modification, termination or cancellation of this Agreement shall be effective
unless in writing signed by both parties hereto.

 

21.            
Identical Counterparts. This Agreement may be executed in one or more counterparts, each of which shall for all purposes
be deemed to be an original but all of which together shall constitute but one and the same Agreement. Only one such counterpart
need be produced to evidence the existence of this Agreement.

 

22.            
Notices. All notices, requests, demands and other communications hereunder shall be in writing and shall be deemed to have
been duly given (i) upon delivery if delivered by hand to the party to whom such communication was directed or (ii) upon the third
business day after the date on which such communication was mailed if mailed by certified or registered mail with postage prepaid:

 

(a)            
If to Indemnitee, at the address indicated on the signature page hereof.

 

(b)            
If to the Corporation, to:

 

Actinium Pharmaceuticals, Inc.

275 Madison Avenue, 7th Floor

New York, NY 10016

Attention:CEO

 

or to such other address as may have been furnished
to Indemnitee by the Corporation.

 

22.            Headings.
The headings of the sections of this Agreement are inserted for convenience only and shall not be deemed to constitute part of
this Agreement or to affect the construction hereof.

 

[Remainder of Page Intentionally Left
Blank]

 

    	 	10	 

     

    

 

IN WITNESS WHEREOF,
the parties hereto have executed this Indemnification Agreement on and as of the day and year first above written.

 

	 	COMPANY:
	 	 
	 	ACTINIUM PHARMACEUTICALS, INC.
	 	 	 
	 	By:	/s/ Sandesh Seth
	 	Name:	Sandesh Seth  
	 	Title:	Chairman & CEO

 

	 	INDEMNITEE:
	 	 
	 	/s/ Dale L. Ludwig
	 	Dale L. Ludwig
	 	 
	 	Address for notices:
	 	 
	 	No. 21 Fernwood Road
	 	Rockaway, NJ 07866-2028

 

 

 

 

 

 

 

 

Signature
Page to Indemnification AgreementExhibit 10.59

 

 

January 31, 2018

 

Mr. Anil Kapur

7 Wellington Drive

Basking Ridge, NJ 07926

 

Dear Mr. Kapur,

 

On behalf of Actinium
Pharmaceuticals, Inc. (the “Company”), I am pleased to offer you the position of Chief Commercial Officer. Speaking
for myself, as well as the other members of the Company’s Board of Directors (the “Board”), we are all
very impressed with your credentials and look forward to your future success in this position.

 

1. Position. The terms of your new
position with the Company are as set forth below:

 

(a) You
shall serve as Chief Commercial Officer.

 

You shall report to the
Chief Executive Officer or appropriate company officer, as designated by the CEO or his designee, and shall perform your duties
for the Company at the Company’s offices in New York City, except for travel that may be necessary or appropriate in connection
with the performance of your duties hereunder. The offices of the Company are currently located in New York City at 275 Madison
Avenue, 7th Floor, New York, NY 10016.

 

(b) You
agree to devote your best efforts and substantially all of your business time to advance the interests of the Company and to discharge
adequately your duties hereunder.

 

2. Start Date.
Subject to fulfillment of any conditions imposed by this letter agreement, you will commence this new position with the Company
no later than February 12th, 2018, provided however. that the start date may be as early as February 6, 2018 upon mutual agreement
between you and the Company (the “Start Date”), subject to Board approval prior to the Start Date. The Company
has the right to withdraw this Offer if you are unable to fulfill the Start Date requirement.

 

3. Proof of Right
to Work. For purposes of federal immigration law, you will be required to provide to the Company documentary evidence of your
identity and eligibility for employment in the United States. Such documentation must be provided to us within three (3) business
days of your date of hire, or our employment relationship with you may be terminated.

 

    

     

    

 

4. Compensation.

 

(a) Base
Salary. You will be paid an annual base salary of Three Hundred Twenty Five Thousand dollars ($325,000), which will be paid in
accordance with the Company's regular payroll practices.

 

(b) Performance
Bonus. You shall be entitled to participate in an executive bonus program, which shall be established by the Board pursuant to
which the Board may award bonuses of up to 35% to you, based upon the achievement of written individual and corporate objectives
such as the Board shall determine.

 

(c) Stock
Option Grant. The Board has agreed to grant you an option grant to purchase 475,000 common shares of the Company (the “Grant”)
and is subject to approval by the Compensation Committee.

 

(i) Stock Options.
Such options will have an exercise price equal to the “Grant Date”).

 

(ii) Vesting Schedule. Twenty-eight percent
(28%) of the initial options or restricted stock granted shall vest twelve months after the date of grant and two percent (2%)
of the remainder shall vest each month thereafter until closing price of the Company’s common stock on your first day of
employment (the fully vested. Such additional options or restricted stock will have an exercise price per share which is equal
to fair market value as determined by the Board on the date of the grant. Two percent (2%) of such additional options or stock
shall vest each month thereafter until fully vested. The term of all options granted under this Agreement will be for 10 years
from the date of grant, subject to your continuing service with the Company. The options or restricted stock will be incentive
stock options or stock to the maximum extent allowed by the tax code and will be subject to the terms of the Company’s Amended
and Restated 2014 Stock Plan, as amended, and the Stock Option Agreement between you and the Company.

 

5. Benefits.

 

a. Benefit plan –
Health Insurance. The Company will provide you with the opportunity to participate in the standard benefits plans currently
available to other similarly situated employees. The Company reserves the right to cancel and/or change the benefits plans it offers
to its employees at any time, subject to applicable law.

 

b. Vacation; Sick
Leave. You will be entitled to 20 days paid vacation per year, pro-rated for the remainder of this calendar year. Vacation
may not be taken before it is accrued. You will be entitled to 5 days paid sick leave per year pro-rated.

 

c. Other Benefits.
The Company will provide you with standard business reimbursements (including mileage, supplies, long distance calls), subject
to Company policies and procedures and with appropriate receipts. In addition, you will receive any other statutory benefits required
by law.

 

    2

     

    

 

d. Reimbursement of
Expenses. You shall be reimbursed for all normal items of travel and entertainment and miscellaneous expenses reasonably incurred
by you on behalf of the Company provided such expenses are documented and submitted in accordance with the reimbursement policies
in effect from time to time.

 

6. Confidential
Information and Invention Assignment Agreement. Your acceptance of this offer and commencement of employment with the Company
is contingent upon the execution, and delivery to an officer of the Company, of the Company’s Confidential Information and
Invention Assignment Agreement, a copy of which is enclosed for your review and execution (the “Confidentiality Agreement”),
prior to or on your Start Date.

 

7. At-Will Employment.
Your employment with the Company will be on an “at will” basis, meaning that either you or the Company may terminate
your employment at any time for any reason or no reason, without further obligation or liability.

 

8. Non-Competition.
During the term and for a period of three (3) years thereafter, you shall not, either directly or indirectly, engage (as principal,
partner, employee, consultant, owner, independent contractor, advisor or otherwise, with or without compensation) in any business
that directly or indirectly is developing, or plans to develop, radioimmunotherapies for cancer or any therapy related to bone
marrow transplant (the “Competing Business”). Notwithstanding the foregoing, this does not prevent you from being engaged
or employed with a business that has a Competing Business as part of its business, so long as you are not engaged or involved in
any way in the Competing Business at such business or enterprise.

 

9. Non-Solicitation.
You agree that during the term of your employment with the Company, and for a period of 24 months following the cessation of employment
with the Company for any reason or no reason, you shall not directly or indirectly solicit, induce, recruit or encourage any of
the Company’s employees or consultants to terminate their relationship with the Company, or attempt any of the foregoing,
either for yourself or any other person or entity. For a period of 24 months following cessation of employment with the Company
for any reason or no reason, you shall not attempt to negatively influence any of the Company’s clients or customers from
purchasing Company products or services or to solicit or influence or attempt to influence any client, customer or other person
either directly or indirectly, to direct his or its purchase of products and/or services to any person, firm, corporation, institution
or other entity in competition with the business of the Company.

 

    3

     

    

 

10. Arbitration.
Any dispute or claim arising out of or in connection with your employment with the Company (except with regard to enforcement of
the Confidentiality Agreement) will be finally settled by arbitration in New York, New York in accordance with the Commercial Arbitration
Rules of the American Arbitration Association by one arbitrator appointed in accordance with said rules. Judgment on the award
rendered by the arbitrator may be entered in any court having jurisdiction thereof. The parties agree that this Agreement evidences
a transaction involving interstate commerce and that the operation, interpretation and enforcement of this arbitration provision,
the procedures to be used in conducting an arbitration pursuant to this arbitration provision, and the confirmation of any award
issued to either party by reason of such arbitration, is governed exclusively by the Federal Arbitration Act, 9 U.S.C. § 21
et seq. Notwithstanding the foregoing, the parties may apply to any court of competent jurisdiction to compel arbitration in accordance
with this paragraph, without breach of this arbitration provision.

 

11. Miscellaneous.
This Agreement, together with the Confidentiality Agreement, sets forth the terms of your employment with the Company and supersedes
any prior representations or agreements, whether written or oral. This Agreement may not be modified or amended except by a written
agreement, signed by the Company and by you. Whenever possible, each provision of this Agreement will be interpreted in such manner
as to be effective and valid under applicable law, but if any provision of this Agreement is held to be invalid, illegal or unenforceable
in any respect under any applicable law or rule in any jurisdiction, such invalidity, illegality or unenforceability will be lessened
or reduced to the extent possible or will be severed and will not affect any other provision and this Agreement will be reformed,
construed and enforced in such jurisdiction as if such invalid, illegal or unenforceable provision had never been contained herein.
This Agreement will be governed by New York law without reference to rules of conflicts of law. All notices, requests, demands
and other communications called for hereunder shall be in writing and shall be deemed given (i) on the date of delivery if delivered
personally, (ii) one (1) day after being sent by a well established commercial overnight service, (iii) three (3) days after being
mailed by registered or certified mail, return receipt requested, prepaid and addressed to the parties or their successors at the
following addresses, or at such other addresses as the parties may later designate in writing, (iv) upon confirmation of facsimile
transfer, if sent by facsimile or (v) upon confirmation of delivery when directed to the electronic mail address set forth below,
if sent by electronic mail:

 

	 	If to the Company:	275 Madison Avenue, Suite 702
	 	 	New York,
NY 10016
	 	 	 
	 	If to you:	Anil Kapur
	 	 	7 Wellington Drive
	 	 	Basking Ridge, NJ 07926

 

We are all delighted
to be able to extend you this offer and look forward to working with you. To indicate your acceptance of the Company’s offer,
please sign and date this letter in the space provided below and return it to me, along with a signed and dated copy of the Confidentiality
Agreement.

 

(signature page follows)

 

    4

     

    

 

	Very truly yours, 	 	ACCEPTED AND AGREED:
	 	 	 	 
	ACTINIUM PHARMACEUTICALS, INC.	 	ANIL KAPUR
	 	 	 	 
	By: 	/s/ Sandesh Seth	 	/s/ Anil Kapur
	 	 	 	Signature
	Name: Sandesh Seth	 	 
	Title: Chief Executive Officer	 	 

 

 

5

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