Document:

Exhibit 4.5(a)

AMENDMENT TO

UNIT PURCHASE OPTION

This AMENDMENT TO UNIT
PURCHASE OPTION (this “Amendment”), dated November 14, 2006, is made by and
between Harbor Acquisition Corporation, a Delaware corporation (the “Company”)
and Ferris, Baker Watts Incorporated (“Holder”), to that certain Unit Purchase
Option referred to below.

WHEREAS, the Company issued
that certain Unit Purchase Option, dated May 1, 2006 (the “Unit Purchase Option”)
in connection with the Company’s initial public offering and Holder is the
owner of the Unit Purchase Option; and

WHEREAS, the parties hereto
have agreed that the Unit Purchase Option be amended as set forth herein to
clarify the understanding between the parties with respect to the terms of the
Unit Purchase Option effective as of the date of its issuance,

NOW, THEREFORE, in
consideration of the premises and of the agreements contained herein, the
parties hereto hereby agree as follows:

1.             Amendment
to the Unit Purchase Option. 
To reflect the original intention of the parties, Section 5 of the Unit
Purchase Option is and shall be amended by adding the following sentence at the
end thereof:

“In no event shall the registered Holder of this
Purchase Option be entitled to (i) to require the payment of cash in lieu of
the issuance of shares upon exercise of this Purchase Option or otherwise “net-cash
settle” the warrants, or (ii) receive any damages if any or all of the
securities evidenced by this Purchase Option have not been registered by the
Company pursuant to an effective registration statement unless the Company has
failed to use its best efforts to have the securities registered.”

2.             Reference
to and Effect on the Unit Purchase Option.  Upon the due execution and delivery of this
Amendment by the parties hereto, on and after the date hereof each reference in
the Unit Purchase Option to this “Purchase Option”, “hereunder,” “hereof,” “herein,”
or words of like import referring to the Unit Purchase Option shall mean and be
a reference to the Unit Purchase Option, as amended hereby.  Except as specifically amended above, the
Unit Purchase Option shall remain in full force and effect and is hereby
ratified and confirmed.

3.             Execution
in Counterparts.  This
Amendment may be executed in one or more counterparts, and by the different
parties hereto in separate counterparts, each of which shall be deemed to be an
original, but all of which taken together shall constitute one and the same
agreement, and shall become effective when one or more counterparts has been
signed by each of the parties hereto and delivered to each of the other parties
hereto.

IN WITNESS WHEREOF, the
parties have executed this Amendment To Unit Purchase Option as of the date set
forth above.

	
  

  	
  HARBOR ACQUISITION CORPORATION

  
	
   

  	
   

  
	
   

  	
  By:

  	
  /s/ Robert J. Hanks

  
	
   

  	
   

  	
  Robert J. Hanks, Chief Executive Officer

  
	
   

  	
   

  
	
   

  	
   

  
	
   

  	
  FERRIS, BAKER WATTS INCORPORATED

  
	
   

  	
   

  
	
   

  	
  By:

  	
  /s/ Scott Bass

  
	
   

  	
   

  	
  Name: Scott Bass

  
	
   

  	
   

  	
  Title: Vice PresidentExhibit 10.1

SECURITIES
PURCHASE AGREEMENT

SECURITIES
PURCHASE AGREEMENT (this “Agreement”), dated as of November 17, 2006, by
and between VIVUS, Inc., a Delaware corporation (the “Company”), and the
investors named on Exhibit A hereto (each an “Investor” and
collectively the “Investors”).

WITNESSETH

WHEREAS, the
Company has filed with the Securities and Exchange Commission (the “Commission”)
a Registration Statement (as defined below) relating to the offer and sale from
time to time of the Company’s securities, including shares of its Common Stock,
$0.001 value (“Common Stock”);

WHEREAS, the
Company is offering for sale shares of Common Stock (the “Offered Shares”)
to the Investors pursuant to the Registration Statement; and

WHEREAS, each
Investor, severally and not jointly, desires to purchase from the Company
Offered Shares on the terms and conditions set forth herein.

NOW, THEREFORE, in
consideration of the recitals (which are deemed to be a part of this
Agreement), mutual covenants, representations, warranties and agreements
contained herein and other good and valuable consideration, the receipt and
sufficiency of which are hereby acknowledged, the parties hereto agree as
follows:

1.             Definitions.  As used herein, the following terms have the
meanings indicated:

“Person” shall mean any individual, partnership, limited
liability company, joint venture, firm, corporation, association, trust or
other enterprise or any government or political subdivision or any agency,
department or instrumentality thereof.

“Prospectus” shall mean the prospectus forming a part of the
Registration Statement and the prospectus supplement relating to the Offered
Shares in the form first filed pursuant to Rule 424(b) under the
Securities Act, as amended (the “Securities Act”), as further amended or
supplemented prior to the execution of this Agreement, and shall include all
information and documents incorporated by reference in such prospectus.

“Registration Statement” shall mean the registration statement
on Form S-3 (File No. 333-135793), including a prospectus, relating
to the offer and sale of certain of the Company’s Common Stock, which was
declared effective by the Commission on August 16, 2006.  References herein to the term “Registration
Statement” as of any date shall mean such effective registration statement, as
amended or supplemented to such date, including all information and documents
incorporated by reference therein.

 

2.             Purchase of Common
Stock.  Subject and pursuant to the
terms and conditions set forth in this Agreement, the Company agrees that it
will issue and sell to the Investor and the Investor agrees that it will
purchase from the Company, the number of Offered Shares set forth on Schedule I
attached hereto (the “Investor Shares”). 
The aggregate purchase price for the Investor Shares (the “Aggregate
Purchase Price”) and the purchase price per Investor Share is set forth on Schedule I
hereto.  The closing of the purchase and
sale of the Investor Shares will be on the date and at the time set forth on Schedule I
hereto, or such other date or time as the parties may agree upon in writing
(the “Closing”).

3.             Deliveries at
Closing.

(a)           Deliveries by the Investor.  At the Closing, each Investor shall deliver
to the Company the Aggregate Purchase Price by wire transfer of immediately
available funds to an account designated by the Company as set forth on Schedule I
hereto, which funds will be delivered to the Company in consideration of the
Investor Shares issued at the Closing.

(b)           Deliveries by the Company.  At the Closing, the Company shall deliver to
each Investor the Investor Shares through The Depository Trust Company DWAC
system to the account that the Investor has specified in writing to the
Company.

4.             Representations,
Warranties, Covenants and Agreements.

(a)           Investor Representations, Warranties and
Covenants.  Each Investor, severally
and not jointly, represents, warrants and agrees as follows:

(1)           Investor has received copies of the
Registration Statement and the Prospectus, including all documents and information
incorporated by reference therein and amendments thereto, and understands that
no Person has been authorized to give any information or to make any
representations that were not contained in the Registration Statement and the
Prospectus, and Investor has not relied on any such other information or
representations in making a decision to purchase the Investor Shares.  Investor hereby consents to receiving
delivery of the Registration Statement and the Prospectus, including all
documents and information incorporated by reference therein and any amendments
thereto, by electronic mail.

(2)           Investor acknowledges that it has sole
responsibility for its own due diligence investigation and its own investment
decision, and that in connection with its investigation of the accuracy of the
information contained or incorporated by reference in the Registration
Statement and the Prospectus and its investment decision, Investor has not
relied on any representation or information not set forth in this Agreement,
the Registration Statement or the Prospectus.

(3)           The execution and delivery of this Agreement
by Investor and the performance of this Agreement and the consummation by
Investor of the transactions contemplated hereby have been duly authorized by
all necessary (corporate, partnership or limited liability in the case of a
corporation, partnership or limited liability company) action of Investor, and
this Agreement, when duly executed and delivered by Investor, will constitute a
valid and legally binding 

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instrument, enforceable in accordance with its terms against Investor,
except as enforcement hereof may be limited by the effect of any applicable
bankruptcy, insolvency, reorganization or similar laws or court decisions
affecting enforcement of creditors’ rights generally and except as enforcement
hereof is subject to general principles of equity (regardless of whether
enforcement is considered in a proceeding in equity or at law).

(4)           No state, federal or foreign regulatory
approvals, permits, licenses or consents are required for Investor to enter
into this Agreement or purchase the Investor Shares.

(b)           Company Representations, Warranties and
Covenants.  The Company hereby
represents, warrants and agrees as follows:

(1)           The Company has been duly incorporated and has
a valid existence and the authorization to transact business as a corporation
under the laws of the State of Delaware, with corporate power and authority to
own its properties and conduct its business as described in the Prospectus, and
has been duly qualified as a foreign corporation for the transaction of
business and is in good standing under the laws of each other jurisdiction in
which it owns or leases properties or conducts any business so as to require
such qualification, except for such jurisdictions wherein the failure to be so
qualified and in good standing would not individually or in the aggregate have
a material adverse effect on the business, results of operations or financial
condition of the Company and its subsidiaries taken as a whole (a “Material
Adverse Effect”).

(2)           Each subsidiary of the Company has been duly
incorporated and is validly existing as a corporation in good standing under
the laws of its jurisdiction of incorporation, with corporate power and
authority to own its properties and conduct its business as described in the
Prospectus, and has been duly qualified as a foreign corporation for the
transaction of business and is in good standing under the laws of each other
jurisdiction in which it owns or leases properties or conducts any business so
as to require such qualification, except for such jurisdictions wherein the
failure to be so qualified and in good standing would not individually or in
the aggregate have a Material Adverse Effect. 
All subsidiaries and their respective jurisdictions of incorporation are
identified on Schedule II hereto. 
Except as disclosed in Schedule II, all of the outstanding
capital stock or other voting securities of each subsidiary is owned by the
Company, directly or indirectly, free and clear of any lien and free of any
other limitation or restriction (including any restriction on the right to
vote, sell or otherwise dispose of such capital stock or other voting
securities).  There are no outstanding
(i) securities of the Company or any of the subsidiaries of the Company which
are convertible into or exchangeable for shares of capital stock or voting
securities of any subsidiary of the Company or (ii) options or other rights to
acquire from the Company or any subsidiary of the Company, or other obligation
of the Company or any subsidiary of the Company to issue, any capital stock,
voting securities or securities convertible into or exchangeable for capital
stock or voting securities of any subsidiary of the Company (collectively, the “Subsidiary
Securities”).  There are no
outstanding obligations of the Company or any subsidiary of the Company to
repurchase, redeem or otherwise acquire any outstanding Subsidiary Securities.

(3)           The execution, delivery and performance of
this Agreement by the Company and the consummation of the transactions
contemplated hereby are within the corporate powers of the Company and have
been duly authorized by all necessary corporate action on the part 

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of the Company, and this Agreement, when duly executed and delivered by
the parties hereto, will constitute a valid and legally binding instrument of
the Company enforceable in accordance with its terms, except as enforcement
hereof may be limited by the effect of any applicable bankruptcy, insolvency,
reorganization or similar laws or court decisions affecting enforcement of
creditors’ rights generally and except as enforcement hereof is subject to
general principles of equity (regardless of whether enforcement is considered
in a proceeding in equity or at law).

(4)           The Investor Shares have been duly
authorized by the Company, and when issued and delivered by the Company against
payment therefor as contemplated by this Agreement, the Investor Shares will be
validly issued, fully paid and nonassessable, and will conform to the
description of the Common Stock contained in the Prospectus.

(5)           The execution and delivery of this Agreement
do not, and the compliance by the Company with the terms hereof will not,
(i) violate the Certificate of Incorporation (as amended to date) of the
Company or the By-Laws (as amended to date) of the Company,
(ii) result in a breach or violation of any of the terms or provisions of,
or constitute a default under, any indenture, mortgage, deed of trust, loan
agreement or other agreement or instrument to which the Company or any of its
subsidiaries is a party or by which the Company or any of its subsidiaries is
bound or to which any of their properties or assets are subject, or
(iii) result in a violation of, or failure to be in compliance with, any
applicable statute or any order, judgment, decree, rule or regulation of any
court or governmental, regulatory or self-regulatory agency or body having
jurisdiction over the Company or any of its subsidiaries or any of their
properties or assets, except where such breach, violation, default or the
failure to be in compliance would not individually or in the aggregate have a
Material Adverse Effect or adversely affect the ability of the Company to issue
and sell the Investor Shares; and no consent, approval, authorization, order,
registration, filing or qualification of or with any such court or
governmental, regulatory or self-regulatory agency or body is required for the
valid authorization, execution, delivery and performance by the Company of this
Agreement or the issuance of the Investor Shares, except for such consents,
approvals, authorizations, registrations, filings or qualifications as may be
required under the Securities Act or state securities or “blue sky” laws and
have been or will be obtained and which have been or will be made in connection
with the listing of the Investor Shares on the Nasdaq Global Market.

(6)           The Company meets the requirements for the
use of Form S-3 under the Securities Act for the primary issuance of
securities.  The Registration Statement
has been declared effective by the Commission and at the time it became
effective, and as of the date hereof, the Registration Statement complied and
complies with Rule 415 under the Securities Act.  No stop order suspending the effectiveness of
the Registration Statement has been issued and no proceeding for that purpose
has been initiated or, to the Company’s knowledge, threatened by the
Commission.  On the effective date of the
Registration Statement, the Registration Statement complied, on the date of the
Prospectus, the Prospectus will comply, and at the date of the Closing, the
Registration Statement and the Prospectus will comply, in all material respects
with the applicable provisions of the Securities Act and the applicable rules and
regulations of the Commission thereunder; on the effective date of the
Registration Statement, the Registration Statement did not, on the date of the
Prospectus, the Prospectus did not, and at the date of the Closing, the
Registration Statement and the 

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Prospectus, will not, contain an untrue statement of a material fact or
omit to state a material fact required to be stated therein or necessary in
order to make the statements therein, in light of the circumstances under which
they were made (with respect to the Prospectus), not misleading; and when filed
with the Commission, the documents incorporated by reference in the
Registration Statement and the Prospectus, complied or will comply in all
material respects with the applicable provisions of the Securities Exchange Act
of 1934, as amended (the “Exchange Act”), and the applicable rules and
regulations of the Commission thereunder. 
There is no material document of a character required to be described in
the Registration Statement or the Prospectus or to be filed as an exhibit to
the Registration Statement that is not described or filed as required.

(7)           The consolidated financial statements and
financial schedules of the Company included or incorporated by reference in the
Registration Statement and the Prospectus comply as to form with the applicable
accounting requirements of the Securities Act and have been prepared in
conformity with generally accepted accounting principles (except, with respect
to the unaudited consolidated financial statements, for the footnotes and
subject to customary audit adjustments) applied on a consistent basis, are
consistent in all material respects with the books and records of the Company,
and accurately present in all material respects the consolidated financial
position, results of operations and cash flow of the Company and its
subsidiaries as of and for the periods covered thereby.

(8)           There are no material liabilities of the
Company or any subsidiary of the Company of any kind whatsoever, whether
accrued, contingent, absolute, determined, determinable or otherwise, and there
is no existing condition, situation or set of circumstances which could
reasonably be expected to result in such a liability, other than liabilities
disclosed in the consolidated financial statements and financial schedules of
the Company, and other undisclosed liabilities which, individually or in the
aggregate, are not material to the Company and any of its subsidiaries, taken
as a whole.

(9)           Neither the Company nor any of its
subsidiaries has sustained since the respective dates of the latest audited
financial statements included or incorporated by reference in the Registration
Statement and Prospectus any material loss or interference with its business
from fire, explosion, flood or other calamity, whether or not covered by
insurance, or from any labor dispute or court or governmental action, order or
decree, otherwise than as disclosed in or contemplated by the Registration
Statement and Prospectus; and, since the respective dates as of which information
is given in the Registration Statement and Prospectus, there has not been any
material change in the capital stock or long-term debt of the Company or any of
its subsidiaries, the Company and its subsidiaries have not incurred any
material liabilities or obligations, direct or contingent, nor entered into any
material transactions, except for entering into purchase orders in the ordinary
course of business, and there has not been any material adverse change in or
affecting the general affairs, management, financial position, stockholders’
equity or results of operations of the Company and its subsidiaries considered
as a whole, otherwise than as disclosed in or contemplated by the Registration
Statement and Prospectus.

(10)         Other than as disclosed in the Prospectus,
there are no legal, governmental or regulatory proceedings pending to which the
Company or any of its subsidiaries is a party or of which any material property
of the Company or any of its subsidiaries is the subject 

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which, taking into account the likelihood of the outcome, the damages
or other relief sought and other relevant factors, would individually or in the
aggregate reasonably be expected to have a Material Adverse Effect or adversely
affect the ability of the Company to issue and sell the Investor Shares; to the
best of the Company’s knowledge, no such proceedings are threatened or
contemplated by governmental or regulatory authorities or threatened by others.

(11)         The Company and each of its subsidiaries have
good and marketable title to all the real property and owns all other
properties and assets, reflected as owned in the financial statements included
or incorporated by reference in the Registration Statement and the Prospectus,
subject to no lien, mortgage, pledge, charge or encumbrance of any kind except
those, if any, reflected in such financial statements or which are not material
to the Company and its subsidiaries taken as a whole.  The Company and each of its subsidiaries hold
their respective leased real and personal properties under valid and binding
leases, except where the failure to do so would not reasonably be expected to
individually or in the aggregate have a Material Adverse Effect.

(12)         The Company has filed all necessary federal
and state income and franchise tax returns and has paid all taxes shown as due
thereon or has filed all necessary extensions, and there is no tax deficiency
that has been, or to the knowledge of the Company might be, asserted against
the Company or any of its properties or assets that would in the aggregate or
individually reasonably be expected to have a Material Adverse Affect.

(13)         There are no authorized options, warrants,
preemptive rights, rights of first refusal or other rights to purchase, or
equity or debt securities convertible into or exchangeable or exercisable for,
any capital stock of the Company or its subsidiaries other than those
accurately described in the Registration Statement and the Prospectus.  There are no holders or beneficial owners of
securities of the Company having rights to registration thereof whose
securities have not been previously registered or who have not waived such
rights with respect to the registration of the Company’s securities on the
Registration Statement, except where the failure to obtain such waiver would
not individually or in the aggregate reasonably be expected to have a Material
Adverse Effect.

(14)         The Company has not taken and will not take
any action that constitutes or is designed to cause or result, or which might
reasonably be expected to cause or result, under the Exchange Act or otherwise,
in stabilization or manipulation of the price of any security of the Company to
facilitate the sale or resale of the Offered Shares.

(15)         Other than as disclosed in the Prospectus, the
Company together with its subsidiaries owns and possesses all right, title and
interest in and to, or, to the Company’s knowledge, has duly licensed from
third parties, all patents, patent rights, trade secrets, inventions, know-how,
trademarks, trade names, copyrights, service marks and other proprietary rights
(“Intellectual Property”) material to the business of the Company and
each of its subsidiaries taken as a whole as currently conducted and as
described in the Prospectus.  To the
Company’s knowledge and except as would not individually or in the aggregate
have a Material Adverse Effect, there is no infringement or other violation by
third parties of any of the Intellectual Property of the Company.  Neither the Company nor any of its
subsidiaries has received any notice of infringement or misappropriation from
any third party that has not been resolved or disposed of and, to the Company’s
knowledge, neither the Company nor any of its subsidiaries has infringed or 

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misappropriated the Intellectual Property of any third party, which
infringement or misappropriation would individually or in the aggregate have a
Material Adverse Effect.  Further, there
is no pending or, to the Company’s knowledge and except as would not
individually or in the aggregate have a Material Adverse Effect, threatened
action, suit, proceeding or claim by governmental authorities or others that
the Company is infringing a patent, and there is no pending or, to the Company’s
knowledge and except as would not individually or in the aggregate have a
Material Adverse Effect, threatened legal or administrative proceeding relating
to patents and patent applications of the Company, other than proceedings
initiated by the Company before the United States Patent and Trademark Office
and the patent offices of certain foreign jurisdictions which are in the
ordinary course of patent prosecution. 
To the Company’s knowledge, the patent applications of the Company
presently on file disclose patentable subject matter, and the Company is not
aware of any inventorship challenges, any interference which has been declared
or provoked, or any other material fact that (i) would preclude the
issuance of patents with respect to such applications, or (ii) would lead
outside patent counsel for the Company to conclude that such patents, when
issued, would not be valid and enforceable in accordance with applicable
regulations.

(16)         The conduct of the business of the Company and
each of its subsidiaries is in compliance in all respects with applicable laws,
rules and regulations of governmental and regulatory bodies, except where the
failure to be in compliance would not individually or in the aggregate have a
Material Adverse Effect.

(17)         The Company is not, and does not intend to
conduct its business in a manner in which it would become, an “investment
company” within the meaning of the Investment Company Act of 1940, as amended.

(18)         All offers and sales of the Company’s capital
stock prior to the date hereof were at all relevant times registered pursuant
to the Securities Act or exempt from the registration requirements of the
Securities Act and were duly registered with or the subject of an available
exemption from the registration requirements of the applicable state securities
or blue sky laws, except where the failure to do so would not individually or
in the aggregate reasonably be expected to have a Material Adverse Effect.

(19)         The Company has filed with the Nasdaq Global
Market a Notification of Listing of Additional Shares with respect to the
Investor Shares required by the rules of the Nasdaq Global Market and has not
received a notice from the Nasdaq Global Market that such notification is
insufficient.  The offer and sale of the
Offered Shares does not require stockholder approval under Rule 4350 of the
Nasdaq Stock Market Rules.

(20)         Neither the Company nor its subsidiaries nor,
to the best of the Company’s knowledge, any employee or agent of the Company or
its subsidiaries, has made any contribution or other payment to any official
of, or candidate for, any federal, state or foreign office in violation of any
law or of the character required to be disclosed in the Prospectus.

(21)         There is no broker, finder or other party that
is entitled to receive from the Company any brokerage or finder’s fee or other
fee or commission as a result of any transactions contemplated by this
Agreement.

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(22)         There are no outstanding loans, advances
(except normal advances for business expenses in the ordinary course of
business) or guarantees or indebtedness by the Company to, or for the benefit
of, any of the officers or directors of the Company.

(23)         To the extent that the Company or any other
Person acting on its behalf has provided the Investor or its agents or counsel
with any information that the Company believes constitutes material, non-public
information, any such material, non-public information will be disclosed to the
public by the Company no less than 48 hours prior to the Closing.

5.             Conditions.  The obligation of each Investor to purchase
and acquire the Investor Shares hereunder shall be subject to the condition
that all representations and warranties and other statements of the Company
shall be true and correct as of and on each of the date of this Agreement and
the date of the Closing, the condition that the Company shall have performed
all of its obligations hereunder theretofore to be performed, and the following
additional conditions:

(a)           The Prospectus shall have been filed with
the Commission pursuant to Rule 424(b) under the Securities Act within the
applicable time period prescribed for such filing, no stop order suspending the
effectiveness of the Registration Statement or any part thereof shall have been
issued and no proceeding for that purpose shall have been initiated or
threatened by the Commission, and the Investor shall have received the
Prospectus in accordance with the federal securities laws.

(b)           The Offered Shares shall have been
authorized for quotation on the Nasdaq Stock Market, Inc.

6.             Miscellaneous.

(a)           Fees and Expenses.  Each of the parties hereto shall be
responsible for their own expenses incurred in connection with the transactions
contemplated hereby.

(b)           Binding Agreement; Assignment.  This Agreement shall be binding upon, and
shall inure solely to the benefit of, each of the parties hereto, and each of
their respective heirs, executors, administrators, successors and permitted
assigns, and no other person shall acquire or have any right under or by virtue
of this Agreement.  The Investors may not
assign any of these rights or obligations hereunder to any other person or
entity without the prior written consent of the Company.

(c)           Entire Agreement.  This Agreement, including Exhibit A
and Schedules I and II hereto, constitutes the entire
understanding between the parties hereto with respect to the subject matter
hereof and may be amended only by written execution by each of the parties
hereto.  Upon execution by the Company
and the Investors, this Agreement shall be binding on each of the parties
hereto.

(d)           Consent To Jurisdiction.  THIS AGREEMENT SHALL BE ENFORCED, GOVERNED
AND CONSTRUED IN ALL RESPECTS IN ACCORDANCE WITH THE LAWS 

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OF THE STATE OF NEW YORK, WITHOUT GIVING EFFECT TO ITS CONFLICTS OF
LAWS PRINCIPLES.

(e)           Notices.  All notices, requests, consents and other
communication hereunder shall be in writing, shall be mailed by first class
registered or certified mail, or nationally recognized overnight express
courier postage prepaid, and shall be deemed given when so mailed and shall be
delivered as addressed as follows:

if to the Company,
to:

VIVUS, Inc.

1172 Castro Street

Mountain View, CA 94040

Attn: Chief Financial Officer

with a copy mailed
to:

Wilson Sonsini Goodrich & Rosati

650 Page Mill Road

Palo Alto, CA 94304

Attn: Mark Reinstra, Esq.

or to such other Person
at such other place as the Company shall designate to the Investors in writing;
and if to the Investors, at the addresses as set forth on Exhibit A
hereto, or at such other address or addresses as may have been furnished to the
Company in writing.

(f)            Counterparts.  This Agreement maybe executed in any number
of counterparts and by the parties hereto in separate counterparts, each of
which when so executed shall be deemed to be an original and all of which taken
together shall constitute one in the same agreement.

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IN WITNESS WHEREOF, the
parties have executed this Agreement as of the date first above written.

	
   

  	
  VIVUS, Inc.

  
	
   

  	
   

  
	
   

  	
   

  
	
   

  	
  By:

  	
   /s/ Timothy E. Morris

  	
   

  
	
   

  	
   

  	
   Name: Timothy E. Morris

  
	
   

  	
   

  	
   Title: Chief Financial Officer

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