Document:

A copy of the Form of Amended and Restated Employment Agreement

 EXHIBIT 10.6 
 AMENDED AND RESTATED EMPLOYMENT AGREEMENT 
 This AMENDED AND RESTATED EMPLOYMENT AGREEMENT (this
“Agreement”), dated as of                     , 2007, between Indevus Pharmaceuticals, Inc., a Delaware Corporation having a
place of business at 33 Hayden Avenue, Lexington, Massachusetts 02421 (the “Corporation”) and Noah D. Beerman, an individual residing at
                                     (the
“Executive”). 
 WHEREAS, the Corporation and Executive entered into that certain Employment Agreement dated March 31,
2006 (the “Original Employment Agreement”); 
 WHEREAS, the Corporation and Executive desire to amend and restate the
Original Employment Agreement pursuant to Section 10 thereof, all as hereinafter provided; 
 WHEREAS, the Executive, in his capacity as
Executive Vice President and Chief Business Officer of the Corporation, the stock of which is publicly traded, shall be deemed a “specified employee” as defined under Section 409A(a)(2)(B) of the Internal Revenue Code of 1986, as
amended (“Code”); and 
 WHEREAS, this Agreement is intended to comply with Code Section 409A and the guidance
thereunder, and shall be interpreted as operating in accordance therewith to the extent that there is any ambiguity as to the terms of the Agreement. 
 NOW, THEREFORE, in consideration of the premises and the mutual covenants and agreements herein contained, the Parties agree as follows: 
 1. EMPLOYMENT; DUTIES; REPORTING 
 (a) The Corporation engages and employs the Executive,
and the Executive hereby accepts engagement and employment, as Executive Vice President and Chief Business Officer to direct, supervise, and have responsibility for the business development operations of the Corporation and performing such other
services and duties as the Chief Executive Officer or the Board of Directors of the Corporation (the “Board”) shall determine. 
 (b) The Corporation will provide office facilities, secretarial, and clerical support consistent with customary practices of the Corporation. The Executive shall perform his duties hereunder from the Corporation’s executive
offices in Massachusetts or such other locations as the Executive and Corporation may agree, provided, however, that the Executive acknowledges and agrees that the performance by the Executive of his duties hereunder may require significant domestic
and international travel by the Executive. 
 (c) The Executive shall devote his best efforts and entire working time and attention to
the proper discharge of his duties and responsibilities under this Agreement. 
 (d) During the Employment Term, the Executive shall be
required to report to the Chief Executive Officer of the Corporation, or such other officer as may be determined by the Board or a committee designated by the Board. 
 (e) Except upon the prior written consent of the Chief Executive Officer or the Board, during the Employment Term, the Executive will not: (i) accept any other employment; or (ii) engage, directly or
indirectly, in any other business activity (whether or not pursued for pecuniary advantage) that is competitive with, or that places him in a competing position to, the Corporation. Personal passive investments and personal business affairs not
inconsistent with this Agreement, or teaching, writing or publicly speaking are permitted, so long as these activities do not interfere or conflict with the Executive’s duties hereunder. 
  

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 2. TERM 
 Subject to any earlier termination pursuant to Section 6, the Executive’s employment hereunder shall be for a term of three (3) years commencing on October 1, 2007 (the “Effective
Date”) and continuing through the earlier of (a) the third anniversary of such date or (b) the date on which this Agreement is terminated in accordance with Section 6; provided, that unless terminated earlier in accordance
with Section 6, this Agreement shall automatically renew for periods of one (1) year unless either the Executive or the Corporation gives written notice to the other not less than sixty (60) days prior to the date of any such
anniversary of such party’s election not to extend the term of this Agreement. The initial three year term and any successive term shall hereinafter be referred to as the “Employment Term.” 
 3. COMPENSATION 
 As compensation
for the performance of his duties under this Agreement, the Executive shall be compensated as follows:
 (a) Salary; Bonuses, Equity
Awards: 
  

	 	(i)	The Corporation shall pay the Executive an annual base salary (“Base Salary”) at an initial rate of Three Hundred Fifty Five Thousand Dollars ($355,000), payable in
accordance with the usual payroll period of the Corporation, and provided further that following each annual anniversary of the Effective Date, the Executive shall be eligible for an increase in Base Salary as determined by the Compensation
Committee. 

  

	 	 (ii)
	 During the Employment Term, the Corporation shall pay the Executive bonuses pursuant to the Corporation’s Executive
Bonus Plan or similar bonus plan as approved by the Board or the Compensation Committee of the Board. Notwithstanding anything in the Executive Bonus Plan to the contrary, each bonus shall be paid to the Executive in accordance with the terms of
such plan but in no event later than March 15th following the calendar year in which such bonus was earned. 

  

	 	(iii)	The Executive will be eligible to receive options, restricted stock and other Awards, as such term is defined in the Company’s 2004 Equity Incentive Plan (the
“Plan”), during the Employment Term pursuant to the Plan or such other equity plans as may be in effect at any time during the term of this Agreement, as may be granted from time to time by the Compensation Committee of the Board or the
Board. 

 The Corporation shall withhold all applicable federal, state and local taxes, social security and workers’
compensation contributions and such other amounts as may be required by law and any plans pursuant to which such compensation is generated or as agreed upon by the parties with respect to the compensation payable to the Executive pursuant to section
3(a) hereof. 
 (b) Expenses. The Corporation shall reimburse the Executive for all normal, usual and necessary expenses incurred
by the Executive in furtherance of the business and affairs of the Corporation, including reasonable travel and entertainment, against receipt by the Corporation of appropriate vouchers or other proof of the Executive’s expenditures and
otherwise in accordance with the expense reimbursement policies and procedures as may from time to time be adopted by the Board of Directors of the Corporation. Any reimbursements hereunder shall be paid to the Executive promptly in a lump sum in
accordance with such expense reimbursement policies and procedures then in effect but in no event later than the March 15 of the calendar year next following the year in which the Executive incurred the reimbursable expense. 
 (c) Benefits. The Executive shall have the right to participate in and to receive benefits from all present and future life, vacation,
accident, disability, medical, pension, and savings plans and all similar benefits made available generally to executives of the Company. The amount and extent of benefits to which the Executive is entitled shall be governed by any applicable
benefit plan, as it may be amended from time to time. The Executive shall receive no 

  

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less than four (4) weeks paid vacation each year which shall accrue if not used in any year and be paid to Executive or carried forward to subsequent
years consistent with Corporation policy. The Corporation shall also carry D&O Liability Insurance coverage for the benefit of its officers and directors including Executive. 
 (d) Life Insurance. The Corporation shall make available to the Executive and his dependents, such medical, disability, life insurance and
such other health benefits as the Corporation makes available to its senior officers and directors. The Executive’s life insurance coverage shall not be less than $1,000,000. 
 4. NON-COMPETITION 
 (a) The
Executive understands and recognizes that his services to the Corporation are special and unique and agrees that, during the term of this Agreement and, unless such termination is by the Executive pursuant to 6(a)(iii) below and provided the
Corporation is not in material default to Executive on any of its obligations under this Agreement, for a period of one (1) year from the date of termination of his employment hereunder, he shall not in any manner, directly or indirectly, on
behalf of himself or any person, firm, partnership, joint venture, corporation or other business entity (“Person”), enter into or engage in any business engaged in the development of commercialization of products directly competitive with
products of the Corporation, including any subsidiary of the Corporation (a “Subsidiary”), including products under development by the Corporation or a Subsidiary within the geographic area of the Corporation’s business. 

(b) During the term of this Agreement and for one (1) year thereafter, Executive shall not, directly or indirectly, without the prior
written consent of the Corporation, solicit or induce any employee of the Corporation or any affiliate to leave the employ of the Corporation or any affiliate or hire for any purpose any employee of the Corporation or any affiliate or any employee
who has left the employment of the Corporation or any affiliate within six months of the termination of said employee’s employment with the Corporation. 
 (c) During the term of this Agreement and for one (1) year thereafter, the Executive shall not, directly or indirectly, without the prior written consent of the Corporation: 
  

	 	(i)	solicit or accept employment or be retained by any party who, at any time during the term of this Agreement, was a customer or supplier of the Corporation or any affiliate where his
position will be related to the business of the Corporation; or 

  

	 	(ii)	solicit or accept the business of any customer or supplier of the Corporation or any affiliate with respect to products similar to those supplied by the Corporation.

 (d) In the event that the Officer breaches any provisions of this Section 4 or there is a threatened breach, then, in
addition to any other rights which the Corporation may have, the Corporation shall be entitled, without the posting of a bond or other security, to injunctive relief to enforce the restrictions contained herein. In the event that an actual
proceeding is brought in equity to enforce the provisions of this Section 4, the Officer shall not urge as a defense that there is an adequate remedy at law nor shall the Corporation be prevented from seeking any other remedies which may be
available. 
 5. CONFIDENTIAL INFORMATION 
 (a) The Executive agrees that during the course of his employment or at any time after termination, he will not disclose or make accessible to any other person, the Corporation’s products, services and
technology, both current and under development, promotion and marketing programs, lists, trade secrets, litigation information and other confidential and proprietary business information of the Corporation, any Subsidiary or any of its clients. The
Executive agrees: (i) not to use any such information for himself or others; and (ii) not to take any such material or reproductions thereof from the Corporation’s facilities at any time during his employment by the Corporation,
except as required in the Executive’s duties to the Corporation. The Executive agrees immediately to return all such material and reproductions thereof in his possession to the Corporation upon request and in any event upon termination of
employment. 
  

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 (b) Except with prior written authorization by the Corporation, the Executive agrees not to disclose
or publish any of the confidential, technical or business information or material of the Corporation, any Subsidiary, its clients or any other party to whom the Corporation owes an obligation of confidence, at any time during or after his employment
with the Corporation. 
 (c) The Executive hereby assigns to the Corporation all right, title and interest he may have or may acquire in
all inventions (including patent rights) developed by the Executive during the term of this Agreement (“Inventions”) and agrees that all Inventions shall be the sole property of the Corporation and its assigns, and the Corporation and its
assigns shall be the sole owner of all patents, copyrights and other rights in connection therewith. The Executive further agrees to assist the Corporation in every proper way (but at the Corporation’s expense) to obtain and from time to time
enforce patents, copyrights or other rights on said Inventions in any and all countries. 
 6. TERMINATION 
 (a) The term of this Agreement shall continue for the period set forth in Section 2 hereof unless sooner terminated upon the first to occur of
the following events (the “Termination Date”): 
  

	 	(i)	The death or disability of the Executive; 

  

	 	(ii)	Termination by the Board of Directors of the Corporation for “just cause”. Any of the following actions by the Executive shall constitute “just cause”:

  

	 	(A)	Material breach by the Executive of Section 4 or Section 5 of this Agreement; 

  

	 	(B)	Material breach by the Executive of any provision of this Agreement other than Section 4 or Section 5 or the willful or reckless failure by the Executive to perform his
duties hereunder which breach or failure is not cured by the Executive within fifteen (15) days of notice thereof from the Corporation; or 

  

	 	(C)	The commission by the Executive of any act or fraud or theft against the Corporation or any Subsidiary, or the conviction of the Executive of any criminal act.

  

	 	(iii)	Termination by the Executive for “just cause”. Any of the following actions or omissions by the Corporation shall constitute “just cause”:

  

	 	(A)	Material breach by the Corporation of any provision of this Agreement which is not cured by the Corporation within fifteen (15) days of notice thereof from the Executive;

  

	 	(B)	Any action by the Corporation to intentionally harm the Executive; or 

  

	 	(C)	A Change in Control of the Corporation (as defined below). 

  

	 	(iv)	Termination by the Board of Directors of the Corporation without “just cause”. 

  

	 	(v)	Termination by the Executive for any reason other than “just cause”. 

 (b) Upon termination pursuant to subparagraphs (i), (ii) or (v) of paragraph
(a) above, the Executive (or his estate in the event of termination pursuant to subparagraph (i)), shall be entitled to receive the Base Salary, bonuses and reimbursement of business expenses accrued but unpaid as of the date of termination.
Any unpaid, accrued salary, bonuses and expense reimbursements should be paid within thirty (30) days of the date of termination and no later than the March 15th after the calendar year of the termination of employment of the Executive under subparagraph (i), (ii) or (v) of paragraph 6(a). 
 (c) Upon termination pursuant to subparagraph (a)(iii)(A) or (B) above, the Executive shall be entitled to receive an amount equal to twelve
(12) months of Base Salary plus a bonus incentive equal to the target bonus set 

  

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forth in the Executive’s bonus plan in effect as of the Termination Date as if such targets had been achieved. At the discretion of the Corporation
(except if the Executive elects to receive monthly installments), (i) such Base Salary may be paid either in one lump sum or in monthly installments throughout the remaining term of this Agreement, and (ii) such bonus incentive amount may
be paid either in one lump sum or in monthly installments for up to twenty four (24) months from the Termination Date, provided that reference is made to the limitations in Section 6(k) below and that for (i) or (ii), monthly
installments may only be selected if they would not trigger a taxable event under Section 409A of the Code. 
 (d) Upon termination
pursuant to subparagraph (a) (iii)(C) above, the Executive shall be entitled to receive an amount equal to eighteen (18) months of Base Salary plus a bonus incentive equal to the target bonus set forth in the Executive’s bonus plan in
effect as of the Termination Date as if such targets had been achieved. At the discretion of the Corporation (except if the Executive elects to receive monthly installments), (i) such Base Salary may be paid either in one lump sum or in monthly
installments throughout the remaining term of this Agreement, and (ii) such bonus incentive amount may be paid either in one lump sum or in monthly installments for up to twenty four (24) months from the Termination Date, provided that
reference is made to the limitations in Section 6(k) below and that for (i) or (ii), monthly installments may only be selected if they would not trigger a taxable event under Section 409A of the Code. 
 The commencement of the cash payout will be governed by a standard “double trigger” mechanism approved by the Board and will commence upon the
occurrence of the second trigger (defined below), provided further that if such second trigger does not occur no cash payout shall be due hereunder. The first “trigger” is the “Change of Control” event and the “second
trigger” is the earliest of the following: 
 (i) the Executive is not offered prior to the Change in Control, (1) a comparable
executive position of the acquirer or of the division of the acquirer which assumes the business of the corporation after the Change in Control (comparable to be determined by the Executive in his reasonable discretion) and (2) a total
compensation and benefits package substantially similar (and no less than) to that provided to the Executive under this Agreement; or 
 (ii)
the Executive accepts an employment agreement discussed in (d)(i) above and within twelve (12) months of the effectiveness of such agreement, is terminated without “just cause” (as defined in Section 6(a)(ii) above) or
experiences a “constructive termination” which shall include any of the actions or omissions described in Section 6(a)(iii) above by the acquirer or division thereof. 
 (e) In addition, upon termination pursuant to subparagraph (iii) above, the Corporation shall provide continuation of health benefits for a period
equal to (I) twelve (12) months from the Termination Date if termination was pursuant to subparagraph (iii)(A) or (B) or (II) eighteen (18) months from the Termination Date if termination was pursuant to subparagraph (iii)(C),
each to the extent authorized by and consistent with 29 U.S.C. § 1161 et seq. (commonly known as “COBRA”), with the cost of the regular premium for such benefit shared in the same relative proportion by the Corporation and the
Executive as in effect on the Termination Date. Notwithstanding the foregoing, nothing in this Section 6(e) shall be construed to affect the Executive’s right to receive COBRA continuation entirely at the Executive’s own cost to the
extent that the Executive may continue to be entitled to COBRA continuation after the Executive’s right to cost sharing under this Section 6(e) ceases, provided further the continued health benefits provided hereunder shall supplement, and
not in any manner be construed to replace or otherwise limit, the periods of COBRA continuation that the Executive would have otherwise been entitled to. 
 (f) Upon termination pursuant to subparagraph (iv) above, the Executive shall be entitled to receive an amount equal to twelve (12) months of Base Salary plus a bonus incentive equal to the target bonus set
forth in the Executive’s bonus plan in effect as of the Termination Date as if such targets had been achieved. At the discretion of the Corporation (except if the Executive elects to receive monthly installments), (i) such Base Salary may
be paid either in one lump sum or in monthly installments throughout the remaining term of this Agreement, and (ii) such bonus incentive amount may be paid either in one lump sum or in monthly installments for up to twenty four (24) months
from the Termination Date, provided that reference is made to the limitations in Section 6(k) below and that for (i) or (ii), monthly installments may only be selected if they would not trigger a taxable event under Section 409A of
the Code. 
  

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 In addition, upon termination pursuant to subparagraph (iv) above, the Corporation shall provide
continuation of health benefits for a period equal to the longer of (a) the remainder of the term of this Agreement, or (b) twelve (12) months from the Termination Date to the extent authorized by and consistent with 29 U.S.C. §
1161 et seq. (commonly known as “COBRA”), with the cost of the regular premium for such benefit shared in the same relative proportion by the Corporation and the Executive as in effect on the Termination Date. Notwithstanding the
foregoing, nothing in this Section 6(f) shall be construed to affect the Executive’s right to receive COBRA continuation entirely at the Executive’s own cost to the extent that the Executive may continue to be entitled to COBRA
continuation after the Executive’s right to cost sharing under this Section 6(f) ceases, provided further the continued health benefits provided hereunder shall supplement, and not in any manner be construed to replace or otherwise limit,
the periods of COBRA continuation that the Executive would have otherwise been entitled to. 
 (g) For purposes of this Agreement, a
“Change in Control of the Corporation” shall be deemed to have occurred upon any one of the following events: 
  

	 	(i)	The date on which shares of Common Stock are first purchased pursuant to a tender offer or exchange offer (other than such an offer by the Corporation, any Subsidiary, any employee
benefit plan of the Corporation or of any Subsidiary or any entity holding shares or other securities of the Corporation for or pursuant to the terms of such plan), whether or not such offer is approved or opposed by the Corporation and regardless
of the number of shares purchased pursuant to such offer; 

  

	 	(ii)	The date the Corporation acquires knowledge that any person or group deemed a person under Section 13(d)-3 of the Securities Exchange Act of 1934 (“Exchange Act”)
(other than the Corporation, any Subsidiary, any employee benefit plan of the Corporation or of any Subsidiary or any entity holding shares of Common Stock or other securities of the Corporation for or pursuant to the terms of any such plan or any
individual or entity or group or affiliate thereof which acquired its beneficial ownership interest prior to the date of this Agreement), in a transaction or series of transactions, has become the beneficial owner, directly or indirectly (with
beneficial ownership determined as provided in Rule 13d-3, or any successor rule, under the Exchange Act), of securities of the Corporation entitling the person or group to 30% or more of all votes (without consideration of the rights of any class
or stock to elect directors by a separate class vote) to which all stockholders of the Corporation would be entitled in the election of the Board of Directors were an election held on such date; 

  

	 	(iii)	The date, during any period of two consecutive years, when individuals who at the beginning of such period constitute the Board of Directors of the Corporation cease for any reason
to constitute at least a majority thereof, unless the election, or the nomination for election by the stockholders of the Corporation, of each new director was approved by a vote of at least two-thirds of the directors then still in office who were
directors at the beginning of such period; and 

  

	 	(iv)	The date of approval by the stockholders of the Corporation of an agreement (a “reorganization agreement”) providing for: 

  

	 	(A)	The merger or consolidation of the Corporation with another corporation where the stockholders of the Corporation, immediately prior to the merger or consolidation, do not
beneficially own, immediately after the merger or consolidation, shares of the corporation issuing cash or securities in the merger or consolidation entitling such stockholders to 65% or more of all votes (without consideration of the rights of any
class of stock to elect directors by a separate class vote) to which all stockholders of such corporation would be entitled in the election of directors or where the members of the Board of Directors of the Corporation, immediately prior to the
merger or consolidation, do not, immediately after the merger or consolidation, constitute a majority of the Board of Directors of the corporation issuing cash or securities in the merger or consolidation; or 

  

	 	(B)	The sale or other disposition of all or substantially all the assets of the Corporation. 

  

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 (h) Adjustment. Anything in this Agreement to the contrary notwithstanding, in the event it
shall be determined that as a result of any payment or distribution by the Corporation to or for the benefit of the Executive whether paid or payable or distributed or distributable pursuant to the terms of this Agreement or otherwise (the
“Payments”), the Executive would be subject to the excise tax imposed by Section 4999 of the Internal Revenue Code (the “Code”) or any interest or penalties are incurred by the Executive with respect to such excise tax (such
excise tax, together with any such interest and penalties, are hereinafter collectively referred to as the “Excise Tax”), the Executive shall be entitled to promptly receive an additional payment (a “Gross-Up Payment”) in an
amount such that, after payment by the Executive of all taxes (including any interest or penalties imposed with respect to such taxes), including, without limitation, any income taxes and Excise Tax imposed upon the Gross-Up Payment, the Executive
is in the same after-tax position as if no Excise Tax had been imposed upon the Executive with respect to the Payments, provided further that such Gross-Up Payment shall not exceed $500,000 under any circumstances. 
 Notwithstanding the above provisions of this Section (h), the Executive’s Payments, shall be reduced to an amount (not less than zero) which shall
not cause any portion of the Payments to be subject to Excise Tax, provided that no such reduction shall be made if the Executive’s Payments, after the reduction and after the application of Federal income tax at the highest rate applicable to
individual taxpayers, shall not be greater than the present value (determined in accordance with Section 280G of the Code) of the Payments and any applicable Gross-Up Payment before the reduction but after the application of (i) excise tax
under Section 4999 of the Code and (ii) Federal income tax at the highest rate applicable to individual taxpayers. 
 (i) Cooperation: Pending Litigation 
  

	 	(i)	Upon the request of the Corporation, in connection with any suit, action, proceeding, arbitration or litigation involving the Corporation (a “Litigation”), which
Litigation is directly or indirectly the result of an event, fact or occurrence existing, in whole or in part, prior to the Termination Date, Executive agrees to, at the expense of the Corporation, in connection with any such Litigation:

  

	 	(A)	attend depositions, meetings, conferences or other scheduled proceedings related to the Litigation with a designated officer of the Corporation; 

  

	 	(B)	provide a written outline of any actions taken by Executive on behalf of the Corporation, or any information known to Executive; and 

  

	 	(C)	otherwise cooperate with the Corporation, counsel to the Corporation and with other parties or entities whom the Corporation shall reasonably request. 

  

	 	(ii)	Unless Executive and the Corporation agree otherwise, Executive shall not be required to engage or participate in any of the activities described in Section 6(i) of this
Agreement for more than three (3) consecutive business days at a time, or more than six (6) business days per ninety (90) day period. 

 (j) SPECIFIED EMPLOYEE STATUS. Notwithstanding anything herein to the contrary, if the Executive is deemed a specified employee, as defined under §409A(a)(2)(B)(i) of the Internal Revenue Code of 1986, as
amended, as of the date of his separation from service for any reason, then the payment dates hereunder shall be adjusted so that no payment of deferred compensation hereunder that is subject to §409A may be made before the expiration of six
(6) months after the date of the Executive’s separation from service, or if earlier, the Executive’s death. 
 (k)
Notwithstanding anything herein to the contrary contained herein, with regards to the determination of lump sum or monthly installment payments to be made under Sections 6(c), (d) and (f) above, the Board shall determine the form of
payment not later than the December 31 prior to the calendar year in which the payment hereunder becomes binding, and provided further that any installments designated hereunder are treated as a series of separate payments in substantially
equal amounts payable over such period as the Board irrevocably designates as of the December 31 prior to the year in which the Executive’s right to the amount hereunder becomes binding. 
  

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 7. NOTICES 
 Any notice or other communication under this Agreement shall be in writing and shall be deemed to have been given: when delivered personally against receipt therefore; one (1) day after being sent by Federal
Express or similar overnight delivery; or three (3) days after being mailed registered or certified mail, postage prepaid, return receipt requested, to either party at the address set forth above, or to such other address as such party shall
give by notice hereunder to the other party. 
 8. INDEMNIFICATION 
 The Corporation will continue to indemnify the Executive pursuant to the indemnification agreement previously entered into between the Corporation and the
Executive which shall remain in force and effect, and otherwise Corporation will enter into an indemnification agreement with the Executive substantially identical to the previously one. 
 9. SEVERABILITY OF PROVISIONS 
 If any provision of this Agreement shall be declared by a court of competent jurisdiction to be invalid, illegal or incapable of being enforced in whole or in part, such provision shall be interpreted so as to remain enforceable to the
maximum extent permissible consistent with applicable law and the remaining conditions and provisions or portions thereof shall nevertheless remain in full force and effect and enforceable to the extent they are valid, legal and enforceable, and no
provision shall be deemed dependent upon any other covenant or provision unless so expressed herein. 
 10. ENTIRE AGREEMENT:
MODIFICATION 
 This Agreement contains the entire agreement of the parties relating to the subject matter hereof, and the parties hereto
have made no agreements, representations or warranties relating to the subject matter of this Agreement which are not set forth herein. No modification of this Agreement shall be valid unless made in writing and signed by the parties hereto.

 11. BINDING EFFECT 
 The rights, benefits, duties, and obligations under this Agreement shall inure to, and be binding upon, the Corporation, its successors and assigns, and upon the Executive and his legal representatives. This Agreement constitutes a personal
service agreement, and the performance of the Executive’s obligations hereunder may not be transferred or assigned by the Executive. 
 12. NON-WAIVER 
 The failure of either party to insist upon the strict performance of the terms, conditions and
provisions of this Agreement shall not be construed as a waiver or relinquishment of future compliance therewith, and said terms, conditions and provisions shall remain in full force and effect. No waiver of any term or condition of this Agreement
on the part of either party shall be effective for any purpose whatsoever unless such waiver is in writing and signed by such party. 
 13. GOVERNING LAW 
 The validity, interpretation, enforceability, and performance of this Agreement shall, to the extent
not otherwise preempted by federal law, be governed by and construed in accordance with the law of the Commonwealth of Massachusetts without giving effect to its conflict of state laws principles. 
 14. HEADINGS 
 The headings of
paragraphs are inserted for convenience and shall not affect the interpretation of this Agreement on the day and year first above written. 
  

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 15. TAXES. 
 All payments hereunder shall be subject to applicable withholdings and reported as wages to the applicable state and federal authorities. Notwithstanding anything herein to the contrary, no particular tax result for
the Executive with respect to any income recognized by the Executive in connection with this Agreement is guaranteed, and the Executive shall be responsible for any taxes, penalties and interest imposed on him including, but not limited to, under
Section 409A of the Code in connection with the Agreement. 
 16. ACKNOWLEDGMENT. 
 The Executive acknowledges: (i) that he has consulted with or has had the opportunity to consult with independent counsel of his own choice
concerning this Agreement and has been advised to do so by the Corporation; and (ii) that he has read and understands the Agreement, is fully aware of its legal effect, and has entered into it freely based on his own judgment. 
 [CONTINUED ON FOLLOWING PAGE] 
  

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 17. NO ASSIGNMENT. 
 (a) Neither this Agreement nor any right or interest hereunder shall be assignable by the Executive, his beneficiaries, or legal representatives without the Corporation’s prior written consent; provided that
nothing in this subsection 17(a) shall preclude the Executive from designating a beneficiary to receive, upon his death, any benefit payable hereunder, or the executors, administrators, or other legal representatives of the Executive’s estate
from assigning any rights hereunder to the person or persons entitled thereto. 
 (b) Except as otherwise required by law, without the
Corporation’s prior written consent, no right to receive payments under this Agreement shall be subject to anticipation, commutation, alienation, sale, assignment, encumbrance, charge, pledge, or hypothecation, or to exclusion, attachment,
levy, or similar process or assignment by operation of law, and any attempt, voluntary or involuntary, to effect any such action shall be null, void, and of no effect. 
 The parties have duly executed this Agreement as of the date first written above. 
  

			
	CORPORATION:
	
	INDEVUS PHARMACEUTICALS, INC.
		
	By:	 	  

	Name:	 	Glenn L. Cooper, M.D.
	Title:	 	Chief Executive Officer

  

			
	EXECUTIVE:
	
	  

	Name:	 	Noah D. Beerman

  

 10Form of senior debt seurity-MTN (BREN Linked to a Basket of Global Indices)

 Exhibit 4.01 
 LEHMAN BROTHERS HOLDINGS INC. 
 Buffered Return Enhanced Notes Linked to a Basket of Global Indices Due May 31, 2011

  

			
	Number R-1	  	$2,724,000
	ISIN US5252M0AD98	  	CUSIP 5252M0AD9

 See Reverse for Certain Definitions 
 THIS SECURITY (THIS “SECURITY”) IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN
THE NAME OF A DEPOSITORY OR A NOMINEE THEREOF. UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN CERTIFICATED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITORY TO A NOMINEE OF THE DEPOSITORY OR BY A
NOMINEE OF THE DEPOSITORY TO SUCH DEPOSITORY OR ANOTHER NOMINEE OF THE DEPOSITORY OR BY THE DEPOSITORY OR ANY SUCH NOMINEE TO A SUCCESSOR DEPOSITORY OR A NOMINEE OF SUCH SUCCESSOR DEPOSITORY. UNLESS THIS SECURITY IS PRESENTED BY AN AUTHORIZED
REPRESENTATIVE OF THE DEPOSITORY TO LEHMAN BROTHERS HOLDINGS INC. OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY SECURITY ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS REQUESTED BY AN
AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY (AND ANY PAYMENT IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE
BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 
 LEHMAN BROTHERS
HOLDINGS INC., a corporation duly organized and existing under the laws of the State of Delaware (hereinafter called the “Company”), for value received, hereby promises to pay to CEDE & CO. or registered assigns, at the
office or agency of the Company in the Borough of Manhattan, The City of New York, on the Maturity Date, in such coin or currency of the United States of America at the time of payment shall be legal tender for the payment of public and private
debts, for each $1,000 principal amount of the Securities represented hereby, an amount equal to the Payment at Maturity. THE SECURITIES REPRESENTED HEREBY SHALL NOT BEAR ANY INTEREST. 
 Any amount payable on the Maturity Date hereon will be paid only upon presentation and surrender of this Security. 
 REFERENCE IS HEREBY MADE TO THE FURTHER PROVISIONS OF THIS SECURITY SET FORTH ON THE REVERSE HEREOF WHICH FURTHER PROVISIONS SHALL FOR ALL PURPOSES HAVE
THE SAME EFFECT AS IF SET FORTH AT THIS PLACE. 

 IN WITNESS WHEREOF, Lehman Brothers Holdings Inc. has caused this instrument to be signed by its
Chairman of the Board, its President, its Vice Chairman, its Chief Financial Officer, one of its Vice Presidents or its Treasurer, by manual or facsimile signature under its corporate seal, attested by its Secretary or one of its Assistant
Secretaries by manual or facsimile signature. 
  

							
	Dated: November 29, 2007	  	LEHMAN BROTHERS HOLDINGS INC.	  	
				
	[SEAL]	  	By:	  	  
	  	
		  		  	Vice President	  	
				
		  	Attest:	  	  
	  	
		  		  	Assistant Secretary	  	

  
 TRUSTEE’S CERTIFICATE OF
AUTHENTICATION 
 This is one of the Securities of the series designated therein referred to in the within-mentioned Indenture. 
  

			
	CITIBANK, N.A.
	as Trustee
		
	By:	 	  

		 	    Authorized Officer

  

 2 

 Reverse of Security 
 This Security is one of a duly authorized series of Securities of the Company designated as Buffered Return Enhanced Notes Linked to a Basket of Global Indices Due May 31, 2011 (herein called the
“Securities”). The Company may, without the consent of the holders of the Securities, create and issue additional securities ranking equally with the Securities and otherwise similar in all respects so that such additional
securities shall be consolidated and form a single series with the Securities; provided that no additional securities can be issued if an Event of Default has occurred with respect to the Securities. This series of Securities is one of an indefinite
number of series of debt securities of the Company, issued and to be issued under an indenture, dated as of September 1, 1987, as amended (herein called the “Indenture”), duly executed and delivered by the Company and Citibank,
N.A., as trustee (herein called the “Trustee”, which term includes any successor trustee under the Indenture), to which Indenture and all indentures supplemental thereto reference is hereby made for a description of the rights,
limitations of rights, obligations, duties and immunities thereunder of the Company, the Trustee and the Holders of the Securities. 
 The
Payment at Maturity at the request of the Trustee shall be determined by the Calculation Agent pursuant to the Calculation Agency Agreement. The Trustee shall fully rely on the determination by the Calculation Agent of the Payment at Maturity and
shall have no duty to make any such determination. The Calculation Agent will provide written notice to the Trustee at its New York office, on which notice the Trustee may conclusively rely, of the Payment at Maturity on or prior to 11:00 a.m. on
the Business Day preceding the Maturity Date. 
 All calculations with respect to the Basket Ending Level and the Basket Return will be
rounded to the nearest one hundred-thousandth, with five one-millionths rounded upward (e.g., .876545 would be rounded to .87655); all dollar amounts related to determination of the payment per $1,000 principal amount Security at maturity
will be rounded to the nearest ten-thousandth, with five one hundred-thousandths rounded upward (e.g., .76545 would be rounded up to .7655); and all dollar amounts paid on the aggregate principal amount of Securities per Holder will be
rounded to the nearest cent, with one-half cent rounded upward. 
 This Security is not subject to any sinking fund. 
 If an Event of Default with respect to the Securities shall occur and be continuing, the amounts payable on all of the Securities may be declared due
and payable in the manner and with the effect provided in the Indenture. The amount payable to the Holder hereof upon any acceleration permitted under the Indenture will be equal to the Payment at Maturity calculated as though the date of
acceleration were the Maturity Date and the fifth Business Day immediately preceding the date of acceleration were the Valuation Date. If the maturity of the Securities is accelerated because of an Event of Default, the Company shall, or shall cause
the Calculation Agent to, provide written notice to the Trustee at its New York office, on which notice the Trustee may conclusively rely, and to The Depository Trust Company of the cash amount due with respect to the Securities as promptly as
possible and in no event later than two Business Days after the date of acceleration. 

 The Indenture contains provisions permitting the Company and the Trustee, with the consent of the
holders of not less than 66 2/3% in aggregate principal amount of each series of Securities at the time
Outstanding to be affected (each series voting as a class), evidenced as in the Indenture provided, to execute supplemental indentures adding any provisions to, or changing in any manner or eliminating any of the provisions of the Indenture or of
any supplemental indenture or modifying in any manner the rights of the holders of the Securities of all such series; provided, however, that no such supplemental indenture shall, among other things, (i) change the fixed
maturity of any Security, or reduce the principal amount thereof, or reduce the rate or extend the time of payment of interest thereon, if any, or reduce any premium payable on redemption, or make the principal thereof, or premium, if any, or
interest thereon, if any, payable in any coin or currency other than that hereinabove provided, without the consent of the holder of each Security so affected, or (ii) change the place of payment on any Security, or impair the right to
institute suit for payment on any Security, or reduce the aforesaid percentage of Securities, the holders of which are required to consent to any such supplemental indenture, without the consent of the holders of each Security so affected. It is
also provided in the Indenture that, prior to any declaration accelerating the maturity of any series of Securities, the holders of a majority in aggregate principal amount of the Securities of such series Outstanding may on behalf of the holders of
all the Securities of such series waive any past default or Event of Default under the Indenture with respect to such series and its consequences, except a default in the payment of interest, if any, or the principal of, or premium, if any, on any
of the Securities of such series, or in the payment of any sinking fund installment or analogous obligation with respect to Securities of such series. Any such consent or waiver by the Holder of this Security shall be conclusive and binding upon
such Holder and upon all future holders and owners of this Security and any Securities which may be issued in exchange or substitution hereof, irrespective of whether or not any notation thereof is made upon this Security or such other Securities.

 No reference herein to the Indenture and no provision of this Security or of the Indenture shall alter or impair the obligation of
the Company, which is absolute and unconditional, to pay the Payment at Maturity with respect to this Security. 
 The Securities are
issuable in denominations of $1,000 and any whole multiples of $1,000. 
 The Company, the Trustee, and any agent of the Company or of the
Trustee may deem and treat the registered holder (the “Holder”) hereof as the absolute owner of this Security (whether or not this Security shall be overdue and notwithstanding any notation of ownership or other writing hereon), for
the purpose of receiving payment hereof, or on account hereof, and for all other purposes and neither the Company nor the Trustee nor any agent of the Company or of the Trustee shall be affected by any notice to the contrary. All such payments made
to or upon the order of such registered holder shall, to the extent of the sum or sums paid, effectually satisfy and discharge liability for moneys payable on this Security. 
 No recourse for the payment of the principal of, premium, if any, or interest on this Security, or for any claim based hereon or otherwise in respect
hereof, and no recourse under or upon any obligation, covenant or agreement of the Company in the Indenture or any indenture supplemental thereto or in any Security, or because of the creation of any indebtedness represented 

  

 2 

 
thereby, shall be had against any incorporator, stockholder, officer or director, as such, past, present or future, of the Company or of any successor
corporation, either directly or through the Company or any successor corporation, whether by virtue of any constitution, statute or rule of law or by the enforcement of any assessment or penalty or otherwise, all such liability being, by the
acceptance hereof and as part of the consideration for the issue hereof, expressly waived and released. 
 As provided in the Indenture and
subject to certain limitations therein set forth, the transfer of this Security is registrable in the Security Register, upon surrender of this Security for registration of transfer at the Corporate Trust Office or agency in a Place of Payment for
this Security, duly endorsed by, or accompanied by a written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed by, the Holder hereof or such Holder’s attorney duly authorized in writing, and
thereupon one or more new Securities of this series or of like tenor and of authorized denominations and for the same aggregate principal amount, will be issued to the designated transferee or transferees. 
 The Company intends to treat, and by purchasing this Security, the Holder agrees to treat, for all tax purposes, this Security as a cash-settled
financial contract, rather than as a debt instrument. 
 THE INDENTURE AND THIS SECURITY SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE
WITH THE LAWS OF THE STATE OF NEW YORK. 
 Definitions 
 Set forth below are definitions of the terms used in this Security. 
 “Basket” shall mean
the basket of four indices to which the Securities are linked. The Basket consists of the S&P 500® Index, the Nikkei 225SM Index, the Dow Jones EURO STOXX 50® Index and the Hang Seng® Index. 
 “Basket Ending Level”, as calculated by the Calculation Agent, is
calculated as follows: 
 Basket Starting Level × [1 + (the sum of (Basket Index Return × Index Weighting) 
 for all Basket Indices)] 
 “Basket
Index” refers to each of the S&P 500® Index, the Nikkei 225SM Index, the Dow Jones
EURO STOXX 50® Index and the Hang Seng® Index or any successor to any
of the foregoing. 
 “Basket Index Ending Level” of a Basket Index is the Closing Level of that Basket Index
on the Valuation Date. 
 “Basket Index Return”, as calculated by the Calculation Agent, is calculated as follows for each
Basket Index: 
  

	
	Basket Index Ending Level — Basket Index Starting Level
	Basket Index Starting Level

  

 3 

 “Basket Index Starting Level” for each of the four Basket Indices is as follows:

  

			
	S&P 500® Index	  	1,416.77
	Nikkei 225SM Index	  	14,837.66
	Dow Jones EURO STOXX 50® Index	  	4,195.58
	Hang Seng® Index	  	26,618.19

 “Basket Index Sponsors” shall be as follows: (A) with respect to the
S&P 500® Index, Standard & Poor’s, a division of the McGraw-Hill Companies, Inc., (B) the Nikkei 225SM Index, Nikkei Inc, (C) the Dow Jones EURO STOXX 50® Index, STOXX Limited, (D) the Hang Seng® Index, HSI Services Limited. The Calculation Agent, in its sole discretion, may select new Index Sponsors as described under “Discontinuation of a
Basket Index; Alteration of Method of Calculation.” 
 “Basket Return”, as calculated by the Calculation
Agent, is calculated as follows: 
  

	
	Basket Ending Level — Basket Starting Level
	Basket Starting Level

 “Basket Starting Level” shall equal 100. 
 “Buffer Amount” shall equal 20.00%. 
 “Business Day”, notwithstanding any provision in the Indenture, shall mean any day that is not a Saturday or Sunday and that is not a day on which banking institutions in the City of New York are
authorized or obligated by law to close. 
 “Calculation Agency Agreement” shall mean the Calculation Agency Agreement,
dated as of December 21, 2006 between the Company and the Calculation Agent, as amended from time to time, or any successor calculation agency agreement. 
 “Calculation Agent” shall mean the person that has entered into an agreement with the Company providing for, among other things, the determination of the Payment at Maturity, which term shall, unless
the context otherwise requires, include its successors and assigns. The initial Calculation Agent shall be Lehman Brothers Inc. 
 “Closing Level” of a Basket Index on any Trading Day will equal the official closing level of such Basket Index, or any Successor Index thereto, published following the regular official weekday close of trading for such
Basket Index on that Trading Day. 
 “Closing Price” of a security, on any particular day, means the last reported sales
price for that security on the Relevant Exchange at the scheduled weekday closing time of the 

  

 4 

 
regular trading session of the Relevant Exchange. If, however, the security is not listed or traded on a bulletin board, then the Closing Price of the
security will be determined using the average execution price per share that an affiliate of the Company pays or receives upon the purchase or sale of the security used to hedge the Company’s obligations under the Securities. 
 “Company” shall have the meaning set forth on the face of this Security. 
 “Holder” shall have the meaning set forth on the reverse of this Security. 
 “Indenture” shall have the meaning set forth on the reverse of this Security. 
 “Index Weighting” shall mean, with respect to each Basket Index, the weighting for such Basket Index. The Index Weightings of the four
Basket Indices are as follows: 
  

				
	S&P 500® Index	  	30.00	%
	Nikkei 225SM Index	  	30.00	%
	Dow Jones EURO STOXX 50® Index	  	30.00	%
	Hang Seng® Index	  	10.00	%

 “Market Disruption Event”, with respect to any of the Basket Indices (or any
Successor Index), means: 
  

	 	•	 	 a suspension, absence or material limitation of trading of stocks then constituting 20% or more of the level of such Basket Index (or the relevant Successor Index)
on the Relevant Exchanges for such securities at any time during the one hour period preceding the close of the principal trading session on such Relevant Exchange; 

  

	 	•	 	 a breakdown or failure in the price and trade reporting systems of the primary market of any Relevant Exchange as a result of which the reported trading prices for
stocks then constituting 20% or more of the level of such Basket Index (or the relevant Successor Index) at any time during the one hour period preceding the close of the principal trading session on such Relevant Exchange are materially inaccurate;

  

	 	•	 	 a suspension, absence or material limitation of trading on any major securities exchange for trading in futures or options contracts or exchange traded funds
related to such Basket Index (or the relevant Successor Index) at any time during the one hour period preceding the close of the principal trading session on such exchange; or 

  

	 	•	 	 a decision to permanently discontinue trading in the relevant futures or options contracts or exchange traded funds; 

 in each case as determined by the Calculation Agent in its sole discretion. 
  

 5 

 For the purpose of determining whether a Market Disruption Event exists at any time, if trading in a
security included in a Basket Index (or the relevant Successor Index) is materially suspended or materially limited at that time, then the relevant percentage contribution of that security to the level of such Basket Index (or the relevant Successor
Index) shall be based on a comparison of: 
  

	 	•	 	 the portion of the level of such Basket Index (or the relevant Successor Index) attributable to that security relative to 

  

	 	•	 	 the overall level of such Basket Index (or the relevant Successor Index), 

 in each case immediately before that suspension or limitation. 
 For purposes of determining whether a Market Disruption Event has occurred: 
  

	 	•	 	 a limitation on the hours or number of days of trading will not constitute a Market Disruption Event if it results from an announced change in the regular business
hours of the Relevant Exchange or market; 

  

	 	•	 	 limitations pursuant to the rules of any Relevant Exchange similar to NYSE Rule 80B (or any applicable rule or regulation enacted or promulgated by any other
self-regulatory organization or any government agency of scope similar to NYSE Rule 80B as determined by the Calculation Agent in its sole discretion) on trading during significant market fluctuations will constitute a suspension, absence or
material limitation of trading; 

  

	 	•	 	 a suspension of trading in futures or options contracts on a Basket Index (or the relevant Successor Index) by the primary securities market trading in such
contracts by reason of: 

  

	 	•	 	 a price change exceeding limits set by such exchange or market, 

  

	 	•	 	 an imbalance of orders relating to such contracts, or 

  

	 	•	 	 a disparity in bid and ask quotes relating to such contracts 

 will, in each such case, constitute a suspension, absence or material limitation of trading in futures or options contracts related to such Basket Index (or the relevant Successor Index); and 
  

	 	•	 	 a suspension, absence or material limitation of trading on any Relevant Exchange or on the primary market on which futures or options contracts related to a Basket
Index (or the relevant Successor Index) are traded will not include any time when such market is itself closed for trading under ordinary circumstances. 

 “Maturity Date” shall mean May 31, 2011, unless that day is not a Business Day, in which case the amount equal to the Payment at
Maturity that would otherwise be due on the scheduled Maturity Date will instead be due on the next succeeding Business Day following such scheduled Maturity Date, with the same effect as if paid on the scheduled Maturity Date; provided 

  

 6 

 
that if due to a non-Trading Day or a Market Disruption Event, the Valuation Date is postponed so that it falls less than three Business Days prior to the
scheduled Maturity Date, the Maturity Date will be the third Business Day following the Valuation Date, as postponed. 
 “Participation Rate” shall equal 118%. 
 “Payment at Maturity”, as calculated by the Calculation
Agent for each $1,000 principal amount Security, shall equal: 
  

	 	•	 	 If the Basket Return is positive, $1,000 + [$1,000 × (Basket Return × Participation Rate)] 

  

	 	•	 	 If the Basket Return is equal to or less than zero, and the absolute value of the Basket Return is less than or equal to the Buffer Amount, $1,000.

  

	 	•	 	 If the Basket Return is negative and the absolute value of the Basket Return is greater than the Buffer Amount, $1,000 + [$1,000 × (Basket Return + Buffer
Amount)]. 

 “Place of Payment” shall mean the place or places where the Payment at Maturity on the
Securities is payable. 
 “Pricing Date” shall mean November 21, 2007. 
 “Relevant Exchange” for any security (or any combination thereof) then included in a Basket Index or any Successor Index, means the
primary exchange, quotation system (which includes bulletin board services) or other market of trading for such security. 
 “Securities” shall have the meaning set forth on the reverse of this Security. 
 “Successor
Index” shall mean a S&P 500® Index Successor Index, a Nikkei 225SM Index Successor
Index, a Dow Jones EURO STOXX 50® Index Successor Index and a Hang Seng® Successor Index, each as specified under “Discontinuation of a Basket Index; Alteration of Method of Calculation” with respect to each Basket Index. 
 “Trading Day” means a day, as determined by the Calculation Agent, on which trading is generally conducted (i) on the Relevant
Exchanges for securities included in the Basket Index (or the relevant Successor Index) and (ii) the exchanges on which futures or options contracts related to the Basket Index (or the relevant Successor Index) are traded, other than a day on
which trading on such Relevant Exchange or exchange on which such securities, futures or options contracts are traded is scheduled to close prior to its scheduled weekday closing time. 
 “Trustee” shall have the meaning set forth on the reverse of this Security. 
 “Valuation Date” shall mean May 23, 2011; provided, however, that if the Valuation Date is not a Trading Day or if there is a
Market Disruption Event on such day, with respect to a Basket Index, the Calculation Agent will: 
  

	 	•	 	 with respect to each Basket Index for which such day is a Trading Day and for which a Market Disruption Event has not occurred, determine the Closing
Level of such Basket Index for use in calculating the Basket Index Ending Level by reference to the Closing Level of such Basket Index on that Trading Day; and 

  

 7 

	 	•	 	 with respect to each Basket Index for which such day is not a Trading Day or for which a Market Disruption Event has occurred, determine the Closing
Level of such Basket Index for use in calculating the Basket Index Ending Level by reference to the Closing Level of such Basket Index on the next Trading Day for such Basket Index on which there is not a Market Disruption Event; provided,
however, if a Market Disruption Event with respect to such Basket Index occurs on each of the eight Trading Days following the originally scheduled Valuation Date, then the Calculation Agent shall determine the Closing Level of such Basket Index
for use in calculating the Basket Index Ending Level in accordance with the formula for and method of calculating the Closing Level of such Basket Index last in effect prior to commencement of the Market Disruption Event (or prior to the non-Trading
Day), using the closing price (or, if trading in the relevant securities has been materially suspended or materially limited, its good faith estimate of the closing price that would have prevailed but for such suspension or limitation or non-Trading
Day) on such eighth scheduled Trading Day of each security most recently included in the Basket Index. 

 All terms used
but not defined in this Security are used herein as defined in the Calculation Agency Agreement or the Indenture. 
 Calculation Agent 
 The Calculation Agent will determine, among other things, the Basket Ending Level (including each Basket Index Return and each Basket Index Ending
Level), the Basket Return and the Payment at Maturity, if any, on the Securities. In addition, the Calculation Agent will determine whether there has been a Market Disruption Event or a discontinuation of any Basket Index (or the relevant Successor
Index) and whether there has been a material change in the method of calculating any of the Basket Indices. All calculations, determinations and adjustments made by the Calculation Agent will be at the sole discretion of the Calculation Agent and
will, in the absence of manifest error, be conclusive for all purposes and binding on Holders and on the Company. The Company may appoint a different Calculation Agent from time to time after the date of the original issue of the Securities without
Holders’ consent and without notifying Holders. 
 Discontinuation of a Basket Index; Alteration of Method of Calculation 
 If a Basket Index Sponsor discontinues publication of the related Basket Index and such Basket Index Sponsor or another entity publishes a successor or
substitute index that the Calculation Agent determines, in its sole discretion, to be comparable to the discontinued Basket Index (a “Successor Index”), then the Closing Level of such Basket Index will be determined by reference to the
level of such Successor Index at the close of trading on the Relevant Exchange or market for the Successor Index on any Trading Day. Upon any selection by the Calculation Agent of a Successor Index, the Calculation Agent will cause written notice
thereof to be promptly furnished to the Trustee, to the Company and to the Holders. 
  

 8 

 If a Basket Index Sponsor discontinues publication of the related Basket Index, and such discontinuation
is continuing on any Trading Day, and the Calculation Agent determines, in its sole discretion, that no Successor Index for such Basket Index is available at such time, or if the Calculation Agent has previously selected a Successor Index for such
Basket Index and publication of such Successor Index is discontinued, and such discontinuation is continuing on any Trading Day, or if the Basket Index Sponsor (or the publisher of any Successor Index) fails to calculate and publish an Closing Level
for such Basket Index (or any Successor Index) on any date when it would ordinarily do so in accordance with its customary practice, then the Calculation Agent will determine such Closing Level for such Trading Day or such date. The Closing Level
for such Basket Index will be computed by the Calculation Agent in accordance with the formula for and method of calculating the Basket Index or Successor Index, as applicable, last in effect on the date prior to such discontinuation or failure to
calculate or publish a Closing Level for the Basket Index or Successor Index, as applicable, using the Closing Price (or, if trading in the relevant securities has been materially suspended or materially limited, its good faith estimate of the
Closing Price that would have prevailed but for such suspension or limitation) at the close of the principal trading session on such date of each security most recently included in the Basket Index or Successor Index, as applicable. 
 If at any time the method of calculating the Basket Index or a Successor Index, or the level thereof, is changed in a material respect, or if the Basket
Index or a Successor Index is in any other way modified so that the Basket Index or such Successor Index does not, in the opinion of the Calculation Agent, fairly represent the level of the Basket Index or such Successor Index in the absence of such
changes or modifications, then the Calculation Agent will, at the close of business in New York City on each date on which the Closing Level for such Basket Index is to be determined, make such calculations and adjustments as, in the good faith
judgment of the Calculation Agent, may be necessary in order to arrive at a level of a stock index comparable to the Basket Index or such Successor Index, as the case may be, as if such changes or modifications were not made, and the Calculation
Agent will calculate the Closing Level with reference to the Basket Index or such Successor Index, as adjusted. Accordingly, if the method of calculating the Basket Index or a Successor Index is modified so that the level of the Basket Index or such
Successor Index is a fraction of what it would have been if there had been no such modification (e.g., due to a split in the Index), then the Calculation Agent will adjust its calculation of the Basket Index or such Successor Index in order
to arrive at a level of the Basket Index or the Successor Index as if there had been no such modification (e.g., as if such split had not occurred). 
  

 9 

 The following abbreviations, when used in the inscription on the face of the within Security, shall be
construed as though they were written out in full according to applicable laws or regulations: 
  

							
	TEN COM -	    	as tenants in common	    	UNIF GIFT MIN ACT - _________ Custodian  _________
		    		    	                          (Cust)             
     (Minor)

	TEN ENT -	    	as tenants by the entireties	    	under Uniform Gifts to Minors
	JT TEN -	    	as joint tenants with right of	    	Act	  	  

		    	Survivorship and not as tenants in common	    		  	( State)

 Additional abbreviations may also be used though not in the above list. 
                                       
                   
 FOR VALUE RECEIVED, the
undersigned hereby sells, assigns and transfers unto 
 PLEASE INSERT SOCIAL SECURITY OR 
 OTHER IDENTIFYING NUMBER OF ASSIGNEE 
  

			
	 	 	
	 	 	
	 	 	

  
  

	
	
	 

 (Name and Address of Assignee, including zip code, must be printed or typewritten.) 
  

	
	
	 

 the within Security, and all rights thereunder, hereby irrevocably constituting and appointing 
  

	
	
	 

 to transfer the said Security on the books of the Company, with full power of substitution in the premises.

 Dated: 
 __________________________________________ 
 NOTICE: The signature to this assignment must correspond with the name as it appears
upon the face of the within Security in every particular, without alteration or enlargement or any change whatever. 
 Signature(s) Guaranteed: 

_____________________ 
 THE SIGNATURE(S) SHOULD BE GUARANTEED BY AN
ELIGIBLE GUARANTOR INSTITUTION (BANKS, STOCKBROKERS, SAVINGS AND LOAN ASSOCIATIONS AND CREDIT UNIONS WITH MEMBERSHIP IN AN APPROVED MEDALLION SIGNATURE GUARANTEE PROGRAM), PURSUANT TO S.E.C. RULE 17Ad-15. 
  

 10

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