Document:

EX-10.9

  Exhibit 10.9

  SUBLEASE AGREEMENT

  This Sublease Agreement (this “Sublease”) is dated as of March 10, 2022 (the “Effective Date”), by and between ROADRUNNER SOLUTIONS LLC, a Delaware limited liability company (“Sublandlord”), with an address of One Patriots Park, Bedford, Massachusetts 01730, and HOMOLOGY MEDICINES, INC., a Delaware corporation (“Subtenant”), with an address of One Patriots Park, Bedford, Massachusetts 01730.  All capitalized terms used in this Sublease and not otherwise defined herein shall have the meaning set forth in the Master Lease (as defined below). 

  RECITALS

  A.	Patriots Park Owner, LLC (“Master Landlord”), as successor-in-interest to Bedford Patriots Park, LLC, as landlord, and Sublandlord, as successor-in-interest to Subtenant, as tenant, are parties to that certain Lease Agreement dated December 21, 2017 (the “Original Lease”), as amended by that certain First Amendment to Lease dated as of February 8, 2019 (the “First Amendment”), as amended by that certain Second Amendment to Lease dated as of March 15, 2019 (the “Second Amendment”), as amended by that certain Third Amendment to Lease dated as of November 9, 2021 (the “Third Amendment”), and as amended by that certain Fourth Amendment to Lease dated as of even date herewith (the “Fourth Amendment”, and together with the Original Lease, the First Amendment, the Second Amendment, and the Third Amendment, the “Master Lease”), pursuant to which Sublandlord leases from Master Landlord approximately 91,529 rentable square feet of space (the “Premises”) located on the first (1st) and second (2nd) floors of the building located at One Patriots Park, Bedford, Massachusetts 01730 (the “Building”).

  B.	Sublandlord desires to sublease a portion of the Premises to Subtenant, and Subtenant desires to sublease a portion of the Premises from Sublandlord, pursuant to the terms and conditions of this Sublease.  

  AGREEMENT

  Now, Therefore, for good and valuable consideration, the receipt and adequacy of which is hereby acknowledged, Sublandlord and Subtenant hereby agree as follows:

  1.Subleased Premises. 

  1.1Subleased Premises.  Sublandlord hereby subleases to Subtenant that portion of the Premises set forth on Exhibit A attached hereto and incorporated herein by this reference consisting of approximately 26,850 rentable square feet of space on the first (1st) floor of the Building comprised of: (a) approximately 19,400 rentable square feet of space for Subtenant’s exclusive use outlined on Exhibit A attached hereto (the “Exclusive Subleased Premises”), and (b) approximately 7,450 rentable square feet of space representing Subtenant’s allocated portion of the “Shared Space” outlined on Exhibit A attached hereto (being Rooms 1100, 1101, 1135, 1136, 1136A,  1137, 1145, 1146) for Subtenant’s non-exclusive use together with Sublandlord and any other subtenants or licensees of Sublandlord (collectively, the “Subleased Premises”), and 

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  Subtenant hereby subleases the Subleased Premises from Sublandlord, pursuant to the terms and conditions of this Sublease, the Master Lease, and the Consent (as hereinafter defined), as applicable.  On the Effective Date, Sublandlord shall deliver possession of the Subleased Premises to Subtenant in accordance with this Sublease unless delayed as a result of any cause beyond the reasonable control of Sublandlord.  

  1.2Delivery.  Subtenant acknowledges and agrees that Sublandlord is not obligated to separately demise the Subleased Premises from the remainder of the Premises; provided that effective as of the Sublease Commencement Date (as hereinafter defined), access into the Subleased Premises, other than the Shared Space, shall be limited exclusively to Subtenant and its employees and agents (subject to Sublandlord and Master Landlord’s access rights pursuant to all terms and conditions of the Master Lease, including, without limitation, Article 27 of the Master Lease, as incorporated into this Sublease, and pursuant to Sections 1.1 above and 7.1(m) below) by way of electronic access cards provided to Subtenant.  Notwithstanding the foregoing, Sublandlord shall have the right, subject to (i) Subtenant’s approval not to be unreasonably withheld, conditioned, delayed or denied, (ii) all terms and conditions of the Master Lease, and (iii) Master Landlord’s approval, to separately demise the Subleased Premises at any time during the Sublease Term (“Demising Work”).  Sublandlord and Subtenant shall negotiate in good faith regarding the scope, schedule and budget for the Demising Work, and shall keep Master Landlord reasonably apprised of the same; provided, however, that if the parties cannot reach an agreement within fifteen (15) days of Sublandlord providing notice to Subtenant that it intends to perform the Demising Work, then Sublandlord’s reasonable determinations regarding the scope, schedule and budget for the Demising Work will prevail.  To the extent the Demising Work is undertaken, the Demising Work shall be performed in compliance with this Sublease and the Master Lease, and the cost for such Demising Work shall be paid equally by Sublandlord and Subtenant.  Subtenant shall reimburse Sublandlord for Subtenant’s fifty percent (50%) portion of the costs of the Demising Work within thirty (30) days of receiving an invoice therefor; provided that if Sublandlord and Subtenant do not agree on the budget under the prior sentence, Subtenant’s fifty percent (50%) portion of the costs of the Demising Work will not exceed $150,000.00.  Subtenant acknowledges and agrees that any Demising Work at any time shall not entitle Subtenant to any abatement of rent, constitute an eviction of Subtenant, constructive or otherwise, or impose upon Sublandlord any liability whatsoever, including but not limited to liability for consequential damages or loss of business by Subtenant; provided that such Demising Work, if any, shall be undertaken in compliance with the terms and conditions set forth in the Master Lease and shall not materially interfere with Subtenant’s business in the Subleased Premises or its use of or access to the Subleased Premises; provided further that Subtenant acknowledges and agrees that such Demising Work will and may cause dust and noise and require Subtenant to move its personal property to allow for such Demising Work and Sublandlord will not be required to perform the Demising Work outside of normal business hours unless requested by Subtenant and Subtenant pays any additional cost related to such after-hours work.

  1.3Subtenant’s Access.  Subject to any supervening events of force majeure, emergencies, casualty or condemnation, and to the rights of the Master Landlord under the Master Lease, Sublandlord will provide Subtenant, its employees and invitees access, on a non-exclusive basis, to the Subleased Premises through the main entrance (Suite 1100), the employee entrance (Suite 1108), the collaboration/laboratory entrance (Suite 1207), the laboratory corridor (suite 1161A), the egress corridor (Suite 1005) and the loading dock twenty-four (24) hours each day, 

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  seven (7) days per week.  Access shall be provided in the form of an electronic card key or badge system for the Building.  All such access shall be subject to such reasonable rules and regulations as Sublandlord and Master Landlord shall impose from time to time and all terms and conditions of the Master Lease.  Except to the extent of Sublandlord’s gross negligence or willful misconduct, Sublandlord shall have no liability to Subtenant, its employees, agents, invitees or licensees for losses due to theft or burglary, or for damages done by unauthorized persons on the Subleased Premises or the Building, and Sublandlord shall not be required to insure against any such losses.  Prior to the substantial completion of the Demising Work, except to the extent of its gross negligence or willful misconduct, Subtenant shall have no liability to Sublandlord or the Sublandlord Parties (as defined below) for losses due to theft or burglary, or for damages done by unauthorized persons on the Subleased Premises or the Building, and Subtenant shall not be required to insure against any such losses.  Sublandlord shall provide Subtenant, at Sublandlord’s sole cost and expense, with one access card for each of Subtenant’s initial employees working in the Subleased Premises as of the Sublease Commencement Date, totaling one hundred fifteen (115) cards.  For each additional or replacement key/card, Subtenant shall pay to Sublandlord as Other Charges the amount set forth on Schedule A attached hereto and incorporated herein.  

  1.4Cooperate.  Sublandlord and Subtenant covenant and agree to reasonably cooperate with each other, and Subtenant further covenants and agrees to reasonably cooperate with any other subtenant or occupant to which Sublandlord subleases or otherwise permits occupancy of the Premises, in connection with the scheduling and use of the Shared Space.   

  1.5Sublandlord’s Data and Telecommunications.  Provided it does not materially interfere with Subtenant’s business, access to or quiet enjoyment of the Subleased Premises (however, subtenant acknowledges that such work may result in levels of noise, dust, obstruction of access, etc. which are in excess of that present currently in the Subleased Premises), Sublandlord reserves the right to extend utility or other similar wiring or cabling through the Subleased Premises to support other areas of the Premises, in a mutually agreeable location or locations within the Subleased Premises; provided that such wiring and/or cabling shall be placed behind walls, above drop ceilings or in such other locations that do not reduce the useable square footage of the Exclusive Subleased Premises and Sublandlord shall repair any damage done in and to the Exclusive Subleased Premises in connection with such installation.  In connection with the exercise of Sublandlord’s rights under this Section 1.5, Sublandlord shall use commercially reasonable efforts to minimize any interference with Subtenant’s use of or access to the Subleased Premises, and any such exercise of Sublandlord’s rights under this Section 1.5 shall be subject to Master Landlord’s prior consent to the extent required by the Master Lease and all terms and conditions of the Master Lease.

  1.6Subtenant’s Data and Telecommunications. 

  (a)The Premises are currently equipped with Subtenant’s information technology (“IT”) systems, switches and switching equipment, racks, wiring, cabling, telecommunications, antenna, communication equipment, and like equipment or systems.  Sublandlord and Subtenant acknowledge and agree that Sublandlord shall have the right to use certain of Subtenant’s IT pursuant to all terms and conditions of the Master Lease and a separate agreement while Sublandlord develops and installs its own IT systems, switches and switching 

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  equipment, racks, wiring, cabling, telecommunications, antenna communication equipment, and like equipment or systems.  

  (b)Notwithstanding anything to the contrary set forth in this Sublease or in any other agreement between Sublandlord and Subtenant, and subject to all terms and conditions of the Master Lease, Sublandlord and Subtenant shall have equal rights to use and access the existing server room located in Room 1145 of the Building (“Server Room”) in the Premises for wiring and the storage of such party’s IT server rack and cabinet.  Neither Sublandlord nor Subtenant makes any warranty or representation to the other as to whether the existing Server Room (including its existing HVAC, if any) and conduit is capable of supporting such party’s current, planned or future IT server rack, cabinet and equipment.  If any modifications to the Server Room and/or Subtenant’s IT equipment, conduit or systems are needed to accommodate Sublandlord’s planned, existing or future IT equipment (including but not limited to additional HVAC), any such modification shall be made pursuant to and in accordance with all terms and conditions of the Master Lease and at the sole cost and expense of Sublandlord, with the prior reasonable consent of Subtenant and, to the extent required by the Master Lease, Master Landlord.

  (c)Sublandlord and Subtenant and each of their designated employees shall have access to the Server Room at all reasonable times.   

  2.Term.  The term of this Sublease (the “Sublease Term”) shall commence on the Effective Date (the “Sublease Commencement Date”), and shall expire on December 31, 2024 (“Sublease Expiration Date”), unless earlier terminated pursuant to the terms of this Sublease.  

  3.Use.  Subtenant shall use and occupy the Subleased Premises in compliance with the Master Lease, and solely for conducting Subtenant’s business in accordance with the Permitted Use (provided that Subtenant shall not have the right to use the Subleased Premises for biomanufacturing uses under the Master Lease unless consented to by Sublandlord, such consent not to be unreasonably withheld, provided that it will not be unreasonable for Sublandlord to withhold such consent if Sublandlord is currently using or planning to use the all or most of the square footage of the Premises permitted to be allocated to biomanufacturing under the Master Lease), and for no other purpose unless Master Landlord and Sublandlord, each in their sole and absolute discretion, otherwise consents in writing.  Notwithstanding the foregoing, Sublandlord acknowledges that Subtenant shall have the right to engage in biomanufacturing to the extent that Sublandlord does not require additional square footage for biomanufacturing under the allocation in the Master Lease and does not cause Sublandlord to be in default under the Master Lease.  Sublandlord makes no representation or warranty regarding the compliance of the Subleased Premises with Applicable Laws, including without limitation the Americans with Disabilities Act of 1990, as amended (the “ADA”).  As between Sublandlord and Subtenant, Sublandlord shall have no responsibility for compliance with Applicable Laws, including without limitation the ADA, with respect to the Subleased Premises except to the extent arising from any Alterations (as such term is defined in Section 8 of the Lease) made by Sublandlord after the Effective Date (including, without limitation, the Demising Work).

  4.Rent.  Sublandlord shall be responsible for the timely payment of Base Rent and Additional Rent under the Master Lease and otherwise complying with the obligations of 

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  Sublandlord under the Master Lease before and during the Sublease Term.  Subtenant shall pay to Sublandlord the following as Sublease Rent hereunder: 

  4.1Sublease Term Rent; Rent Commencement Date.  Beginning on the Sublease Commencement Date, and continuing during the Sublease Term, Subtenant shall pay to Sublandlord, as sublease rent (“Monthly Rent”) and in lieu of the Base Rent set forth in the Master Lease, in lawful money of the United States of America, without any deduction, offset, prior notice or demand, in advance on the first date of each month of the Sublease Term from the Sublease Rent Commencement Date through the Sublease Expiration Date, an amount equal Subtenant’s Share of the Monthly Base Rent payable by Sublandlord with respect to the Premises, plus Subtenant’s Share of Additional Rent (as defined in the Master Lease) to be paid by Sublandlord with respect to the entire Premises under the Master Lease in and for the Sublease Term, excluding any late fees, damages or penalties arising from Sublandlord’s breach of the Master Lease (other than those, if any, resulting from Subtenant’s failure to comply with this Sublease).  As used herein, “Subtenant’s Share” means:  30.15% (calculated by dividing the square footage of the Subleased Premises by the total square footage of the Premises), which shall be adjusted if the Premises leased by Sublandlord under the Master Lease is adjusted.  Notwithstanding anything to the contrary contained herein, during any free rent period for the Expansion Premises under Section 7(a) of the Third Amendment, Subtenant shall pay Monthly Rent as though Sublandlord were required to pay Monthly Rent under the Master Lease in full for such period and Subtenant shall have no right to any abatement of Monthly Rent on account of Sublandlord receiving an abatement of Monthly Rent under the Third Amendment.  

  4.2Direct Expenses.  In addition to the Monthly Rent, commencing on the Sublease Commencement Date and continuing during the Sublease Term, Subtenant shall pay to Sublandlord, as Additional Rent, in advance on the first day of each and every calendar month during the Sublease Term, an amount equal to Subtenant’s Share of Tenant’s Share (as defined in the Master Lease) of Master Landlord’s estimate of the Direct Expenses that Sublandlord is charged by Master Landlord pursuant to Article 4 of the Master Lease (the “Direct Expense Rent”), which shall be subject to change by written notice from Sublandlord to Subtenant from time to time as and when Master Landlord changes the estimated monthly payments due by Sublandlord for Tenant’s pro rata share of Direct Expenses under the Master Lease.  Sublandlord shall promptly provide to Subtenant copies of (i) any changes delivered in writing by Master Landlord in the estimated monthly payments due by Sublandlord for Tenant’s Share of Direct Expenses under the Master Lease and (ii) Direct Expense statements that Sublandlord receives from Master Landlord.  If Master Landlord changes the estimated monthly payments due by Sublandlord for Tenant’s Share of Direct Expenses under the Master Lease in writing or if Sublandlord reconciles the actual Tenant’s Share of Direct Expenses due by Sublandlord under the Master Lease with Master Landlord for any calendar year during the Sublease Term, Sublandlord shall provide such change and/or reconciliation in an estimate of Direct Expenses or Direct Expense statement to Subtenant and shall also reconcile the Direct Expense Rent with Subtenant in accordance with Subtenant’s Share.  Sublandlord shall credit any overpayments to Subtenant against the next Monthly Rent payment due by Subtenant, provided that Sublandlord has received a refund or credit of such overpayment from Master Landlord, and Subtenant shall pay any shortfall in the estimate of actual costs within thirty (30) days following delivery of the change in any estimates of Direct Expenses or Direct Expense statement to Subtenant.

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  4.3Other Charges.  In addition to Monthly Rent and (without duplication of) Direct Expenses Rent under Section 4.2 above, commencing on the Sublease Commencement Date and continuing during the Sublease Term, Subtenant shall pay Sublandlord, as “Sublease Additional Rent”, (i) Subtenant’s Share of (x) all costs charged to Sublandlord by Master Landlord or utility or service provider for any service or utility furnished to the extent such utility or service is provided to and utilized by the Subleased Premises, and (y) any and all other amounts of Additional Rent (as defined in the Master Lease) that are charged to Sublandlord by Master Landlord or payable by Sublandlord to any third party pursuant to the provisions of the Master Lease or otherwise, and in the case of each of subsections (x) and (y), to the extent such cost arise out of utilities and/or services provided to and utilized by the Subleased Premises, including, without limitation, all utilities paid by Sublandlord under Article 6 of the Master Lease, whether to Master Landlord or a third party provider; (ii) any and all charges incurred by Sublandlord that are specifically attributable exclusively to Subtenant, the Subleased Premises, or Subtenant’s operations therein or Subtenant’s Alterations made to the Subleased Premises, and not shared with any other portion of the Premises or Sublandlord; and (iii) any and all charges, actually incurred for services requested by Subtenant that Sublandlord is liable to Master Landlord or any third party provider or which relate to services that Master Landlord is not obligated to provide at no additional cost under the Master Lease (each being, and collectively, “Other Charges”).  Such Other Charges, if not paid directly to the Master Landlord by Subtenant (which payment shall be made on or before the due date), shall be paid to Sublandlord for remittance to Master Landlord within thirty (30) days of being billed to Subtenant by Sublandlord.  If Subtenant pays such Other Charges directly to Master Landlord, Subtenant shall provide documentation of such payment within five (5) days after such payment is made.  Sublandlord shall deliver to Subtenant a copy of any statement received by Sublandlord from the Master Landlord reflecting all such Sublease Additional Rent including those attributable 100% to Subtenant.  Additionally, if Sublandlord shall be charged by reason of Subtenant’s acts or defaults under this Sublease for any sums pursuant to the provisions of the Master Lease, then Subtenant shall be liable for such sums with respect to the Subleased Premises, and such sums shall be deemed Sublease Additional Rent and collectible as such and shall be payable by Subtenant within thirty (30) days’ written notice from Sublandlord.     

  4.4“Sublease Rent” Defined.  All Monthly Rent, Direct Expense Rent, Sublease Additional Rent and other monetary obligations of Subtenant to Sublandlord under the terms of this Sublease are deemed to be rent (“Sublease Rent”).  Sublease Rent shall be paid promptly when due, and without deduction, abatement, counterclaim or setoff of any amount or for any reason whatsoever.  Sublandlord shall have the same remedies for default in payment of Direct Expense Rent and Other Charges as Sublandlord has for default in payment of Monthly Rent.  Except Direct Expense Rent or as otherwise expressly stated herein, Sublease Additional Rent will become due thirty (30) days after the date of Subtenant’s receipt of Sublandlord’s invoice therefor.  Sublease Rent shall be payable in lawful money of the United States to Sublandlord by ACH or wire transfer to an account that Sublandlord may designate in writing.  Sublease Rent payable for any partial month during the Sublease Term shall be prorated on a daily basis based on the actual number of days in such month.  No payment by Subtenant or receipt or acceptance by Sublandlord of any lesser amount than the amount stipulated to be paid hereunder shall be deemed other than on account of the earliest stipulated Sublease Rent; nor shall any endorsement or statement on any check or letter be deemed an accord and satisfaction, and Sublandlord may accept any check or payment without prejudice to Sublandlord’s right to recover the balance due or to pursue any other remedy available to Sublandlord in this Sublease or at law.      

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  5.Condition of Subleased Premises.  Subtenant is subleasing the Subleased Premises in its “as is” condition existing as of the Sublease Commencement Date, and Sublandlord shall have no obligation to furnish, render or supply any allowance, work, labor, services, material, fixtures, equipment or decorations to make the Subleased Premises ready for Subtenant’s occupancy.  The taking of possession of each portion of the Subleased Premises by Subtenant shall be conclusive evidence as against Subtenant that such portion of the Subleased Premises was in satisfactory condition at the time possession was taken.  In making and executing this Sublease, Subtenant has relied solely on such investigations, examinations and inspections as Subtenant has chosen to make or has made.  Subtenant acknowledges that no representations have been made to it by Sublandlord with respect to the condition of the Subleased Premises.  Other than as set forth in this Sublease, all maintenance (including all routine maintenance contracts), repair and, as necessary, replacement to maintain the Exclusive Subleased Premises in the condition required under the Master Lease shall be the responsibility of Subtenant at Subtenant’s sole cost and expense during the Sublease Term.

  6.Subtenant’s Alterations; Sublandlord’s Consent.

  6.1Subtenant’s Proposed Alterations.  Notwithstanding anything to the contrary in the Master Lease or this Sublease, provided that Sublandlord has granted its prior written consent for Subtenant to make Alterations (“Subtenant’s Proposed Alterations”) to the Subleased Premises in accordance with Section 6.2 below, Subtenant shall be permitted to seek Master Landlord’s consent for Subtenant to make Subtenant’s Proposed Alterations to the Subleased Premises and Subtenant shall have the use of the Sublease Allowance for such purposes.  Except for the Sublease Allowance, Subtenant shall provide a copy of all correspondence with Master Landlord regarding Subtenant’s Proposed Alterations to Sublandlord within three (3) business days after Subtenant giving or receiving such correspondence, as applicable.  Subtenant shall be solely responsible for any and all costs relating to approval and performance of the construction of Subtenant’s Proposed Alterations, including, without limitation, architectural plans, inspections, alterations, legal fees, permits, and compliance with laws and regulations, and thereafter for any and all costs relating to maintenance, repair, replacement and removal of the Subtenant’s Proposed Alterations.  Subtenant shall be solely responsible for obtaining and paying for all necessary permits in connection with the construction of any Subtenant’s Proposed Alterations.

  6.2Sublandlord’s Consent to Subtenant’s Proposed Alterations.  Subtenant shall not make or cause, suffer or permit the making of any Alterations in or to the Subleased Premises, without in each instance, first (i) obtaining the prior written consent of Master Landlord and of Sublandlord, which, if Master Landlord has granted consent, will be granted in Sublandlord’s reasonable discretion (provided that denial of such consent by Sublandlord will not be deemed unreasonable with respect to any Alterations that, without limitation, (w) are for expanding the square footage of the Subleased Premises used as a vivarium beyond the existing vivarium in a the Subleased Premises or otherwise require a change in the Permitted Use, (x) would reasonably be expected to materially adversely affect or interfere with Sublandlord’s or any other tenant’s business operations in the Premises, (y) would reasonably be expected to materially adversely affect the Building structure or systems or materially increase Sublandlord’s costs of operating the Premises or (z) would be visible from the exterior of the Subleased Premises), to install such proposed Alterations; and (ii) complying with this Sublease and the Master Lease.  If 

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  any Subtenant’s Proposed Alterations are made without Master Landlord’s or Sublandlord’s consent as required under this Section 6, Master Landlord or Sublandlord may remove the same, and may correct, repair and restore the Subleased Premises and any damage arising from such removal, and Subtenant shall be liable for all costs and expenses incurred by Sublandlord and all costs and expenses incurred by Master Landlord in the performance of such removal and restoration work.  Subtenant acknowledges and agrees that Sublandlord shall bear no cost or expense relating to any Subtenant’s Proposed Alterations, including the review thereof or the installation, maintenance and repair of any approved Alterations. Any and all of Subtenant’s Proposed Alterations shall be performed by Subtenant pursuant to and in accordance with all terms and conditions of the Master Lease.

  6.3Removal of Alterations.  At the expiration or earlier termination of this Sublease, and without limitation of Subtenant’s other surrender obligations below, Subtenant shall remove all Alterations then in the Subleased Premises:  (a) if such Alterations existed in the Subleased Premises as of the Effective Date, to the extent that Master Landlord notified Subtenant that such Alterations would be required to be removed at the expiration or earlier termination of the Lease Term or Master Landlord preserved its right to require removal and/or restoration of such Alterations in accordance with Section 8.3 of the Master Lease, the presumption being, as between Sublandlord and Subtenant, that, absent Master Landlord delivering written evidence to the contrary, no removal is required or Master Landlord did not reserve the right to so require, except that Sublandlord and Subtenant hereby acknowledge there is a removal requirement for the generator pad previously constructed by Subtenant, and (b) if such Alterations are constructed by Subtenant after the Effective Date, to the extent that Master Landlord and/or Sublandlord notify Subtenant in writing, at the time Subtenant specifically requests consent to such Alterations, that such Alterations will be required to be removed at the expiration or earlier termination of the Sublease Term in accordance with Section 8.3 of the Master Lease, provided further that it is hereby acknowledged that Master Landlord may preserve its right to require removal and/or restoration of such Alterations in accordance with Section 8.3 of the Master Lease, and, in each case, repair all damage resulting from such removal.  Subtenant shall indemnify Sublandlord and Master Landlord from and against any costs, fees or liabilities incurred by Sublandlord or Master Landlord (including, without limitation, under the Master Lease) by reason of any of Alterations made by Subtenant to the Subleased Premises, including, without limitation, all costs and expenses incurred by Master Landlord or Sublandlord with respect to Subtenant’s failure to remove any Alterations made by Subtenant in or to the Subleased Premises as required under this Section 6.  Subtenant's obligations under this Section 6 shall survive the termination of this Sublease.  Except to the extent provided in Section 7(b) below or pursuant to the terms and conditions of the Master Lease, Subtenant shall not place, inscribe, paint or affix or otherwise display any sign, advertisement, picture, lettering or notice of any kind on any part of the Shared Space, Premises or exterior or interior common areas of the Building (including windows and doors) or on any part of the interior of Subleased Premises which can be seen from outside the Subleased Premises.

  7.Master Lease. 

  7.1Sublease Subordinate to Master Lease; Subtenant’s Covenants.  This Sublease is in all respects subject and subordinate to all of the terms, provisions, covenants, stipulations, conditions and agreements of the Master Lease and to the matters to which the Master Lease is or shall be subject and subordinate.  A copy of the Master Lease has been furnished to, 

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  and examined by, Subtenant.  Subtenant agrees as follows: except as otherwise provided in this Sublease, all references in such incorporated provision to the word “Tenant” shall be deemed to refer to Subtenant, all references to the word “Premises” shall be deemed to refer to the Subleased Premises, all references to the term “Lease” shall be deemed to refer to this Sublease, all references to the word “Term” shall be deemed to refer to the Sublease Term, all references to the term “Landlord” shall be deemed to refer to the Sublandlord, and all references to the term “indemnitees” shall be deemed to include reference to the Sublandlord, each unless expressly stated, or the context would imply, otherwise): 

  (a)Basic Lease Provisions.  The provisions of the Master Lease are hereby incorporated herein by reference, except to the extent that they are inapplicable or modified by the provisions of this Section 7 hereof or otherwise by this Sublease for the purpose of incorporation by reference, each and every term, covenant and condition of the Master Lease binding upon or inuring to the benefit of Master Landlord shall, in respect of this Sublease, bind or inure to the benefit of Sublandlord, and each and every term, covenant and condition of the Master Lease binding upon or inuring to the benefit of the Tenant thereunder shall, in respect of this Sublease, bind or inure to the benefit of Subtenant, with the same force and effect as if such terms, covenants and conditions were completely set forth in this Sublease, except for Sections 1, 2.2, 3, 4, 5, 7, 9, 10, 11, 12, and 14 of the Summary of Basic Lease Information, Sections 1.1.1, 1.2, 1.4, 2.1, 2.2, 3, 7, 8.1, 10.7, 14 (except to the extent referenced in Section 7.1(g) below), 23, 29.4, 29.6 (but only the last three sentences), 29.14, 29.15, 29.24 (but only references to “Brokers” and the last sentence) 29.32, 29.33, 29.34 of the Original Lease, Exhibit 1.1.1-1, Exhibit 1.1.1-2, Exhibit 1.4.2, Exhibit 14.1, Exhibit 18 and Exhibit 29.32.1 thereof, the First Amendment (other than subsection 4(b)(iii) and Section 5), the Second Amendment, and Sections 4, 5, 6, 7, 8, 9, 12, 13), 14, 15, 17, 18(b) and (c), 19 (other than the first sentence of the amended to Section 14.2), 21, 23, 25, and Exhibits A, B and C of the Third Amendment.  In no event shall Subtenant have any extension, expansion, contraction, termination, signage (other under Section 7.1(b) below), improvement allowance, roof, parking (other than under Section 7.1(g) below), assignment or subletting, passenger or freight elevator usage to any floor above the first floor or other similar options and rights set forth in the Master Lease.  Notwithstanding anything in the foregoing or elsewhere in this Sublease, nothing in this Sublease shall abridge, diminish or negate any rights of Master Landlord under the Master Lease.

  Neither party shall take any action or do, omit to do, or permit to be done anything (i) in violation of or default under any of the terms, covenants, conditions or provisions of the Master Lease or any other instrument to which this Sublease is subordinate (and Sublandlord shall comply with all of the terms of the Master Lease to the extent Sublandlord remains obligated thereunder or to the extent that Subtenant cannot directly comply with such obligations); or (ii) which could result in any additional cost or other liability to Sublandlord unless Subtenant assumes and pays such cost or liability. 

  Subtenant expressly agrees that, if the Master Lease or Sublandlord’s tenancy, control or right to possession of the Premises shall terminate by expiration or any other cause, including, without limitation, a termination caused by Sublandlord’s exercise of any right of Sublandlord under the Master Lease to terminate the Master Lease by reason of fire, casualty or condemnation, this Sublease shall thereupon immediately cease and terminate and Subtenant shall give immediate possession to Sublandlord; provided, however, that the liability of the Subtenant to the Sublandlord 

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  or the liability of the Sublandlord to the Subtenant for termination caused by the applicable party’s default under this Sublease shall not be discharged by reason of such termination.

  (b)Signage.  Subtenant’s right to install signage for the Subleased Premises shall be limited to the Exclusive Subleased Premises and shall be subject to Sublandlord’s and Master Landlord’s prior approval as to location, size, design and composition (in Sublandlord’s reasonable discretion and Master Landlord’s sole and absolute discretion) and otherwise governed by all terms and conditions of the Master Lease, including, without limitation, Article 23 of the Master Lease.  Subtenant shall have the right to install Exterior Building Signage to the extent approved by Master Landlord, provided that such signage does not diminish Sublandlord’s right to Exterior Building Signage or visually interfere with or obstruct Sublandlord’s Exterior Signage.  The parties shall cooperate, in good faith, to install signage in the shared reception area for each of Sublandlord and Subtenant subject to Sublandlord’s and, to the extent required pursuant to the Master Lease, Master Landlord’s prior approval, as to location, size, design and composition (in Sublandlord’s reasonable discretion and, if applicable, Master Landlord’s sole and absolute discretion).  

  (c)Utilities and Services.  Subtenant’s consumption of utilities shall be subject to all terms and conditions of the Master Lease, including, without limitation, Article 6 of the Master Lease, which is incorporated herein by this reference.  Subtenant and Sublandlord hereby agree that Subtenant shall pay Subtenant’s Share of the cost of such utilities in accordance with Section 4.3 above; provided that if Subtenant’s use of or Alterations to the Subleased Premises causes material increases to the cost of utilities, Subtenant shall pay such additional costs.  Sublandlord shall provide pest control, janitorial and char service for the Shared Space to the extent required by the Master Lease and Subtenant shall pay Subtenant’s Share for such services as Additional Rent in the amount set forth on Schedule A.  All utilities which are separately metered for the Subleased Premises shall be at Subtenant’s sole cost and expense and shall be paid directly to such utility provider.  Any services not furnished through systems or facilities provided or maintained by Master Landlord under the Master Lease shall be the responsibility of Subtenant to obtain, at Subtenant’s sole cost and expense, subject to the terms and conditions of the Master Lease; provided that Sublandlord shall maintain the HVAC, hot water boilers, steam boiler system for the Shared Space, to the extent the same are the responsibility of the tenant under the Master Lease, and Subtenant shall reimburse Sublandlord for Subtenant’s Share of such costs and expenses as Additional Rent in the amount set forth on Schedule A.  In addition, if Subtenant shall require utilities or services in excess of those usually furnished or supplied for tenants in similar spaces in the Building by reason of Subtenant’s equipment or extended hours of business operations, then Subtenant shall first procure Sublandlord’s and, to the extent required under the Master Lease, Master Landlord’s consent for the use thereof, which consent Sublandlord and, to the extent permitted under the Master Lease, Master Landlord may condition upon the availability of such excess utilities or services, and Subtenant shall pay as Sublease Additional Rent an amount equal to the cost of providing such excess utilities and services.  Sublandlord shall provide management, cleaning and restocking of the reception area, café, breakroom, and restrooms in the Shared Space and Subtenant shall reimburse Sublandlord there for as Additional Rent the amount set forth in Schedule A.  Unless expressly set forth in this Sublease, Sublandlord shall not be responsible for the maintenance and repair obligations of the tenant under 6.2.1 of the Master Lease with respect to the Subleased Premises.    

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  (d)Time Limits.  The time limits contained in the Master Lease for the giving of notices, making of demands or performing of any act, condition or covenant on the part of tenant thereunder, for the occurrence of an event of default thereunder or for the exercise by the tenant thereunder of any right, remedy or option required to be performed by the tenant under the Master Lease, are changed for the purposes of incorporation herein by reference by shortening the same in each instance by two (2) business days, so that in each instance Subtenant shall have two (2) business days less time to observe or perform hereunder than Sublandlord has as the tenant under the Master Lease, unless Sublandlord has as tenant under the Master Lease three (3) or fewer days in which event Subtenant shall have the time Sublandlord has as tenant under the Master Lease. 

  (e)Insurance.  On or before the Sublease Commencement Date, and for the duration of the Sublease Term, Subtenant, at Subtenant’s sole expense, shall obtain and maintain for the benefit of Sublandlord and Master Landlord, the insurance types and coverages (and in such form) as are required by Article 10 of the Master Lease to be obtained and maintained by Sublandlord as tenant, which are incorporated herein by this reference, in amounts not less than those specified in the Master Lease, including, without limitation Section 10.3 of the Master Lease, which policies shall be in form and content reasonably satisfactory to Sublandlord. Each policy of liability insurance shall name Sublandlord and Master Landlord as an additional insured and the waiver of subrogation requirements of property policies shall operate between Sublandlord and Subtenant, in the same manner as between Master Landlord and Sublandlord.  Subtenant will cause its insurance carriers to include any clauses or endorsements in favor of Master Landlord and Sublandlord which Sublandlord is required to provide pursuant to the provisions of the Master Lease.  Subtenant’s insurance shall be primary over Master Landlord’s and Sublandlord’s insurance.  Without limitation of the foregoing, such insurance shall not be canceled or modified unless thirty (30) days prior written notice shall have been given to Sublandlord by Subtenant.

  (f)Parking.  During the Sublease Term, Subtenant shall have the right to use Subtenant’s Share of the net total number of parking spaces available to Sublandlord under the Master Lease to park standard size automobiles and small utility vehicles in the parking facilities that serve the Project in accordance with the terms and subject to the conditions set forth in Article 28 of the Master Lease (i.e., Subtenant’s Share shall be calculated after deduction of any parking space reductions for Exterior Equipment and/or Special Systems installations).  

  (g)Assignment and Subletting.  Subtenant shall not assign, mortgage, pledge, hypothecate, encumber or permit any lien to attach to, or otherwise transfer, this Sublease or any of its interest in this Sublease, permit any assignment, or other transfer of this Sublease or any interest hereunder by operation of law, or sub-sublet, license or otherwise permit the use or occupancy of the Subleased Premises or any portion thereof by anyone other than Subtenant (each a “Transfer”) without the prior written consent of (i) Master Landlord and (ii) Sublandlord, which consent may be granted, each in their sole discretion.  Any agreement in breach of the preceding provision shall be void.  In connection with any Transfer requiring Sublandlord’s and/or Master Landlord’s consent under this Sublease and/or Master Landlord’s consent under the Master Lease, the form of sublease or assignment to be used, as applicable, shall be subject to approval by Sublandlord and Master Landlord each in their sole discretion, and Subtenant shall pay Master Landlord’s review and processing fees, as well as professional fees under the Master Lease, and Sublandlord’s reasonable review and processing fees, as well as reasonable professional fees 

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  (including, without limitation, attorneys’ accountants’ architects’ engineers and consulting fees), in any case, whether or not such consent is granted. Provided that Subtenant does not trigger Section 14.4 of the Master Lease, Subtenant may engage in a Transfer that is a Change in Control (as defined below) or an assignment of the entire Sublease without Sublandlord’s consent, and without Master Landlord’s consent if such Transfer is a “Permitted Transfer” under Section 14.8 of the Master Lease.  If Subtenant is a corporation, partnership or trust, any transfer or transfers of or change or changes within any twelve (12) month period in the number of the outstanding voting shares of the corporation, the general partnership interests in the partnership or the identity of the persons or entities controlling the activities of such partnership or trust resulting in the persons or entities owning or controlling a majority of such shares, partnership interests or activities of such partnership or trust at the beginning of such period no longer having such ownership or control (each a “Change in Control”) shall be regarded as a Transfer of this Sublease to the persons or entities acquiring such ownership or control and shall be subject to all the provisions of this Section 7(g) with respect to an assignment of this Sublease to the same extent and for all intents and purposes as though such were an assignment.  Notwithstanding anything to the contrary herein, a Change of Control or an assignment of the Sublease that would otherwise be a Permitted Transfer under the Master Lease shall require Sublandlord’s consent, in its sole discretion, if the persons or entities acquiring such ownership or control are engaged in the business of viral vector process development or manufacturing.  In no event shall any provision of this Sublease limit or modify any right of Master Landlord under Article 14 of the Master Lease.  Notwithstanding the foregoing, any Transfer shall be expressly conditioned upon the prior written consent of Master Landlord, and shall, in all instances, comply with all terms and conditions of the Master Lease.  No Transfer by Subtenant approved by Sublandlord and Master Landlord under this Section 7(g) shall release Subtenant of Subtenant’s obligations under this Sublease.  Any Transferee, whether by a Change of Control or otherwise, shall assume all Subtenant indemnity obligations hereunder as of the Effective Date. 

  (h)Surrender.  Subtenant shall surrender the Subleased Premises upon the expiration or earlier termination of this Sublease in the condition required under all terms and conditions of the Master Lease, including, without limitation, Article 15 of the Master Lease, and Section 6.3 of this Sublease.  Notwithstanding the foregoing, at Sublandlord’s written request given prior to the expiration or earlier termination of the Sublease Term, Subtenant shall surrender the Subleased Premises with those items of Subtenant’s standard office furniture (“Retained Furniture”), an itemized list of which shall be as agreed upon by Sublandlord and Subtenant, and in consideration of Ten Dollars ($10.00) paid by Sublandlord to Subtenant as of such date and such other consideration, the receipt and sufficiency of which is hereby acknowledged by the parties hereto, then Subtenant agrees to sell to Sublandlord all of its right, title and interest in the Retained Furniture on the day immediately preceding the expiration date of the Sublease Term.  

  (i)Casualty; Condemnation.  The restoration obligations of “Landlord” under Articles 11 and 13 of the Master Lease shall be the responsibility solely of Master Landlord and shall not be the responsibility of Sublandlord.  In the event of casualty or condemnation, if the Master Lease is terminated with respect to all or a portion of the Subleased Premises pursuant to the provisions of the Master Lease, this Sublease shall automatically terminate at the same time and Subtenant shall have no claim against Sublandlord or Master Landlord for the loss of its interest hereunder or any of Subtenant's property.  Any election right or option in the Master Lease with respect to restoration of the Premises or the Building or termination of the Master Lease is 

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  expressly reserved to Sublandlord to exercise in its reasonable discretion, and Subtenant shall have a proportional right to abatement (as set forth in this Section)  in connection with any casualty or condemnation of the Subleased Premises or the Building other than by reason of damage resulting from Subtenant’s misuse, negligence, or willful misconduct.  In the event that a certain number of days of Sublandlord’s rental obligations are actually abated by Master Landlord pursuant to Articles 11 or 13 of the Master Lease with regard to the Subleased Premises other than by reason of damage resulting from Subtenant’s misuse, negligence, or willful misconduct, a similar number of days of Subtenant’s rental obligations shall be abated under this Sublease in the same and any such abatement received by Sublandlord shall be proportionately shared with Subtenant based upon the amount of Sublandlord’s rent obligations under the Master Lease relative to the amount of Subtenant’s rental obligations under this Sublease.  In the event the Building (including, without limitation, any part of the Subleased Premises) or any other Common Areas of the Project are damaged or destroyed in whole or in part in circumstances resulting from Subtenant’s misuse, negligence, or willful misconduct, Subtenant shall be solely responsible for, at Subtenant’s sole cost and expense, all repair and restoration as may be required to restore the affected portions of the Project to a condition comparable to that existing immediately prior to the occurrence and for any and all other costs, expenses, claims, liabilities and losses incurred, whether directly or indirectly, by Sublandlord and Master Landlord as a result thereof.

  (j)Estoppel Certificate.  Any statement delivered by Subtenant to Sublandlord pursuant to Article 17 of the Master Lease that has been incorporated herein by reference, may be relied upon by Master Landlord or any mortgagee of Master Landlord or any existing or prospective purchaser, transferee or mortgagee of any or all of the Subleased Premises) and by any prospective assignee or transferee of the leasehold estate under the Master Lease.  Unless otherwise agreed by Master Landlord, in no event shall Master Landlord be obligated to deliver an estoppel certificate to Subtenant.

  (k)Hazardous Materials.  Subtenant expressly acknowledges and agrees that it shall perform all removal, decontamination, compliance, reporting and remediation obligations in respect of the Subleased Premises to the extent required by Section 5.3 of the Master Lease, which has been incorporated herein by reference.  If any written report, including any report containing results of any Environmental Assessment (as defined in the Master Lease) (an “Environmental Report”) shall indicate (i) the presence of any Hazardous Materials as to which Subtenant has a removal or remediation obligation under Section 5.3 of the Master Lease, and (ii) that as a result of same, the investigation, characterization, monitoring, assessment, repair, closure, remediation, removal, or other clean-up (the “Clean-up”) of any Hazardous Materials is required pursuant to Section 5.3 of the Master Lease, Subtenant shall immediately prepare and submit to Sublandlord and Master Landlord within thirty (30) days after receipt of the Environmental Report a comprehensive plan, subject to Sublandlord’s and Master Landlord’s written approval, specifying the actions to be taken by Subtenant to perform the Clean-up so that the Subleased Premises are restored to the conditions required by Section 5.3 of the Master Lease. Upon Sublandlord’s and Master Landlord’s approval of the Clean-up plan, Subtenant shall, at Subtenant’s sole cost and expense, without limitation of any rights and remedies of Sublandlord or Master Landlord under this Sublease, immediately implement such plan with a consultant reasonably acceptable to Sublandlord and Master Landlord and proceed to Clean-Up Hazardous Materials in accordance with all Applicable Laws and as required by such plan and this Sublease.  If, within thirty (30) days after receiving a copy of such Environmental Report, Subtenant fails 

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  either (a) to complete such Clean-up, or (b) with respect to any Clean-up that cannot be completed within such thirty (30) day period, fails to proceed with diligence to prepare the Clean-up plan and complete the Clean-up as promptly as practicable, then Sublandlord shall have the right, but not the obligation, and without waiving any other rights under this Sublease, to carry out any Clean-up recommended by the Environmental Report or required by any governmental authority having jurisdiction over the Subleased Premises, and recover all of the costs and expenses thereof from Subtenant as Additional Rent, payable within ten (10) days after receipt of written demand therefor.

  8.Sublandlord Not Responsible for Representations and Covenants of Master Landlord under Master Lease.  Except as expressly permitted under this Sublease, Subtenant agrees not to contact Master Landlord directly, including, without limitation, concerning the Subleased Premises, Shared Space or any Master Lease or Sublease provision or obligation (e.g., the provisions of any utilities and services under the Master Lease and/or the making of any repairs or restorations).  Sublandlord shall not be deemed to have made any representation made by Master Landlord in the Master Lease in its capacity as the lessor of the Building.  Moreover, during the Sublease Term, Subtenant acknowledges and agrees that Sublandlord shall not be responsible for Master Landlord’s breach of its covenants and obligations under the Master Lease.  Without limiting the generality of the foregoing, Sublandlord shall not be obligated (i) to provide any of the services or utilities that Master Landlord has expressly agreed in the Master Lease to provide, (ii) to make any of the repairs or restorations that Master Landlord has expressly agreed in the Master Lease to make, (iii) to comply with any laws or requirements of public authorities with which Master Landlord has expressly agreed in the Master Lease to comply, or (iv) to make any payment or take any action with respect to the operation, administration or control of the Project, the Premises, the Subleased Premises or any of the Common Areas that the Master Landlord has expressly agreed in the Master Lease to take, and Sublandlord shall have no liability to Subtenant on account of any failure of Master Landlord to do so, or on account of any failure by Master Landlord to observe or perform any of the terms, covenants or conditions of the Master Lease required to be observed or performed by Master Landlord, provided that in the event that Subtenant determines in good faith that Master Landlord has not performed its obligations as expressly set forth under the Master Lease, then upon receipt of written notice from Subtenant, Sublandlord shall be obligated to use reasonable best efforts to cause Master Landlord to resolve such breaches, defaults or failures of Master Landlord under the Master Lease by promptly requesting and pursuing until response of Master Landlord, (i) additional services and/or the making of any repairs or restorations as requested by Subtenant pursuant to the terms and provisions of the Master Lease as incorporated herein and (ii) Master Landlord’s consent for any action to which Sublandlord has consented and, pursuant to the terms and provisions of this Sublease and/or the Master Lease, for which Master Landlord’s consent is required; provided, further however, Sublandlord shall not be required to incur any expense or expend any sums in connection with performing its obligations under the immediately preceding sentence, unless Subtenant prepays such expense and only to the extent of such prepayment, or have any obligation to commence litigation or other dispute resolution proceedings to cause Master Landlord to comply with the Master Lease. Subtenant shall not in any event have any rights in respect of the Subleased Premises greater than Sublandlord’s rights under the Master Lease, and, notwithstanding any provision to the contrary, as to obligations contained in this Sublease by the incorporation by reference of the provisions of the Master Lease or as to any obligation of Master Landlord, Sublandlord shall not be required to make any payment, provide any services or perform any obligation of Master Landlord under the Lease, and 

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  Sublandlord shall have no liability to Subtenant for any matter whatsoever, except for Sublandlord’s obligation to pay the rent and other sums due under the Master Lease and otherwise to perform its obligations under the Master Lease and under this Sublease (other than any such obligations of Sublandlord under the Master Lease to be performed by Subtenant under the express terms of this Sublease), and for Sublandlord’s obligation to make a written demand upon Master Landlord to fulfill its obligations as expressly set forth under the Master Lease, upon request of Subtenant and at Subtenant’s sole cost and expense. Sublandlord shall have no liability to Subtenant, nor shall Subtenant’s obligations under this Sublease be reduced or abated in any manner, by reason of any inconvenience, annoyance, interruption or injury to Subtenant’s business arising from Master Landlord’s making repairs or changes which Master Landlord is required or permitted to make under the Master Lease.  Sublandlord shall not be responsible for any failure or interruption, for any reason whatsoever, of the services or facilities that may be appurtenant to or supplied at the Building by Master Landlord, including, without limitation, heat, air conditioning, water and elevator service; and no failure to furnish, or interruption of, any such services or facilities shall give rise to any (a) abatement, diminution or reduction of Subtenant’s obligations under this Sublease, (b) right to terminate this Sublease or (c) liability on the part of Sublandlord; provided, however, to the extent that a certain number of days of Sublandlord’s rental obligations are abated pursuant to the Master Lease with respect to the Subleased Premises, then a similar number of days of Subtenant’s rental obligations shall be abated under this Sublease other than by reason of damage resulting from Subtenant’s misuse, negligence, or willful misconduct and any such abatement actually received by Sublandlord shall be proportionately shared with Subtenant based upon the amount of Sublandlord’s rent obligations under the Master Lease relative to the amount of Subtenant’s rental obligations under this Sublease.  Nothing contained in this Sublease shall be construed to create privity of estate or of contract between Subtenant and Master Landlord. 

  9.Indemnification.

  9.1Indemnity by Subtenant.  Any applicable non-liability, waiver, release, defense, indemnification or hold harmless provision of the Master Lease for the benefit of Master Landlord under the Master Lease that is incorporated herein by reference, shall be deemed to inure to the benefit of Sublandlord (except to the extent of Sublandlord’s indemnification obligations under Section 9.2 below), Master Landlord, and any other person specifically named to be benefited by said provision, for the purpose of incorporation by reference in this Sublease and shall apply to this Sublease as if each of Master Landlord and Sublandlord was the “Landlord” and Subtenant was the “Tenant” described in the Master Lease (except to the extent of Sublandlord’s indemnification obligations under Section 9.2 below).  Except to the extent caused by the gross negligence or willful misconduct of Sublandlord or the Sublandlord Parties (as defined below) and except for Sublandlord’s indemnification obligations set forth in Section 9.2 below, to the maximum extent permitted pursuant to Applicable Laws, Subtenant hereby assumes all risk of damage to property or injury to persons in, upon or about the Exclusive Subleased Premises from any cause whatsoever (including, but not limited to, any personal injuries resulting from a slip and fall in, upon or about the Exclusive Subleased Premises) and agrees that, to the extent permitted pursuant to Applicable Laws, Sublandlord, the Guarantor (as defined in the Master Lease) its lenders, partners, subpartners and their respective officers, agents, servants, employees, and independent contractors (collectively, “Sublandlord Parties”; provided that for purposes of this Sublease, Subtenant shall be deemed not to be a Sublandlord Party) shall not be liable for, and are hereby released from any responsibility for, any damage either to person or property or resulting 

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  from the loss of use thereof, which damage is sustained by Subtenant or by other persons claiming through Subtenant.  Subtenant shall indemnify, defend, protect, and hold harmless the Sublandlord Parties from any and all loss, cost, damage, injury, expense and liability (including without limitation court costs and reasonable attorneys’ fees) (“Claims”) during the Sublease Term or any period of Subtenant’s occupancy of the Subleased Premises incurred in connection with or arising from (a) any cause in, on or about the Subleased Premises (including, but not limited to, a slip and fall) provided that the terms of the foregoing indemnity shall not apply to the extent of any gross negligence or willful misconduct of Sublandlord or to any Claims for which Sublandlord has an indemnity obligation pursuant to Section 9.2 below, (b) any negligent acts or omissions of Subtenant or of any person claiming by, through or under Subtenant, or of the contractors, agents, servants, employees, invitees, guests or licensees of Subtenant or any such person, in, on or about the Project, (c) any breach of the terms of this Sublease by Subtenant, either prior to, during, or after the expiration of the Sublease Term, or (d) any dispute between Sublandlord and Master Landlord regarding the requirement to remove Alterations that would be subject to Section 6.3 above regardless of the result of the final determination and the costs of removal and restoration of such Alterations in the event of a final determination that removal thereof is required.  Should Sublandlord be named as a defendant in any suit brought against Subtenant in connection with any matter for which Subtenant is required to indemnify Sublandlord under this Section 9.1, Subtenant shall pay to Sublandlord its reasonable costs and expenses incurred in such suit, including without limitation, its actual professional fees such as reasonable appraisers’, accountants’ and attorneys’ fees.  The provisions of this Section 9.1 shall survive the expiration or sooner termination of this Sublease.    

  9.2Indemnity by Sublandlord.  Except to the extent arising from the gross negligence or willful misconduct of Subtenant, Sublandlord shall indemnify Subtenant against all Claims (a) directly caused by the gross negligence or willful misconduct of Sublandlord in the Exclusive Subleased Premises during the Sublease Term, or (b) directly caused by the conduct of the Sublandlord Parties in the Shared Space or of any business of the Sublandlord Parties therein.  The provisions of this Section 9.2 shall survive the expiration or sooner termination of this Sublease.  

  10.Notices.  All notices, consents, approvals, demands and requests (collectively “Notices”) which are required or desired to be given by either party to the other hereunder shall be given in accordance with Section 29.18 of the Master Lease that has been incorporated herein by reference, except that if addressed to: (i) Sublandlord then addressed to Roadrunner Solutions LLC, One Patriots Park, Bedford, Massachusetts 01730, Attention: Tim Kelly, Chief Executive Officer, Email: tim.kelly@homologymedicines.com, and (ii) Subtenant then addressed to Homology Medicines, Inc., One Patriots Park, Bedford, Massachusetts 01730, Attention: Paul Alloway, General Counsel, Email: palloway@homologymedicines.com and with a copy to Latham & Watkins LLP, 200 Clarendon Street, 27th Floor, Boston, Massachusetts 02116, Attention: Peter N. Handrinos and Matthew W. Goulding, Email: Peter.Handrinos@lw.com, except that any notice sent by U.S. mail shall be deemed delivered upon receipt.  Each party hereto may from time to time change the names and/or addresses to which Notices given to it shall be addressed and sent as aforesaid, by designating such other names and/or addresses in a Notice given in accordance with the provisions of this Section.  Further, Subtenant shall promptly, but in all events, not later than three (3) business days after receipt thereof, each furnish to Sublandlord 

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  a copy of each notice, demand or other written communication sent to or received from Master Landlord.

  11.Consents and Approvals.  In any instance when Sublandlord’s consent or approval is required under this Sublease and Sublandlord has agreed not to unreasonably withhold or delay such consent or approval, Sublandlord’s refusal to consent to or approve any matter or thing shall be deemed reasonable if the consent or approval of Master Landlord has not been obtained despite Sublandlord’s repeated requests therefor in accordance with Section 8 above. Sublandlord and Subtenant hereby acknowledge and agree that this Sublease is subject to Sublandlord obtaining the written consent (the “Consent”) of Master Landlord as provided in the Master Lease. It is expressly understood and agreed that notwithstanding anything to the contrary contained herein, the Sublease Term shall not commence, nor shall Subtenant take possession of the Subleased Premises or any part thereof, until the Consent has been obtained.

  12.Sublandlord’s Covenants.  Sublandlord covenants to do the following:

  12.1Sublandlord shall not (1) voluntarily agree with the Master Landlord to, or, pursuant to the terms of the Master Lease, unilaterally, surrender or terminate the Master Lease prior to its scheduled expiration date during the Sublease Term without the consent of Subtenant, provided that Sublandlord shall be permitted without Subtenant’s consent to otherwise terminate the Master Lease pursuant to its terms and conditions (including a termination caused by Sublandlord’s exercise of any right of Sublandlord under the Master Lease to terminate the Master Lease by reason of fire, casualty or condemnation), or (2) amend or modify the Master Lease, the result of which would materially and adversely affect Subtenant’s rights or obligations under this Sublease or the Subleased Premises; 

  12.2Sublandlord shall comply with all the terms and provisions of the Master Lease, except to the extent Subtenant has assumed the same or cause Sublandlord’s non-compliance with any term or provision of the Master Lease, and

  12.3Sublandlord shall, promptly following receipt thereof, deliver to Subtenant a copy of any and all notices received by Sublandlord from Master Landlord which would have any material effect upon the Subleased Premises or this Sublease.

  13.Sublandlord’s Right to Cure Subtenant Default/Subtenant’s Right to Cure Sublandlord Default.  Upon a breach or default by Subtenant under this Sublease, Sublandlord may, after providing prior written notice to Subtenant and without waiving or releasing any obligation of Subtenant hereunder and without waiving any rights or remedies at law or otherwise, make such payment or perform such act.  In the event that Sublandlord provides such payment hereunder, Subtenant shall reimburse Sublandlord for such payments on demand.  In the event of Sublandlord’s failure to pay Rent under the Master Lease by the date due (other than a failure, if any, resulting from Subtenant’s failure to comply with this Sublease) and such failure continues for three (3) business days after notice of such failure is given to Sublandlord by Master Landlord, Subtenant shall have the right (but not the obligation, unless so required by the Master Landlord) on written notice, to provide such payments to Master Landlord unless Sublandlord, at its sole election, within two (2) business days after such written notice from Subtenant (a) provides Subtenant with reasonable assurances that such failure will not cause Sublandlord to be in default 

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  under the Master Lease, or (b) establishes an escrow account to hold such unpaid Rent pending resolution of such failure by Sublandlord and Master Landlord. In the event that Subtenant provides such payment hereunder, Sublandlord shall reimburse Subtenant for such payments on demand.

  14.Entire Agreement; Modification of Sublease.  It is understood and acknowledged that there are no oral agreements between the parties hereto affecting this Sublease and this Sublease constitutes the parties’ entire agreement with respect to the subleasing of the Subleased Premises by Subtenant and supersedes and cancels any and all previous negotiations, arrangements, brochures, agreements and understandings, if any, between the parties hereto or displayed by Sublandlord to Subtenant with respect to the subject matter thereof, and none thereof shall be used to interpret or construe this Sublease, except as by mutual agreement of the parties.  None of the terms, covenants, conditions or provisions of this Sublease can be modified, deleted or added to except in writing signed by the parties hereto.  Should any current or prospective mortgagee or ground lessor for the Building or Project require a modification of this Sublease, which modification will not cause an increased cost or expense to Subtenant or in any other way materially and adversely change the rights and obligations of Subtenant hereunder, then and in such event, Subtenant agrees that this Sublease may be so modified and agrees to execute whatever documents are reasonably required therefor and to deliver the same to Sublandlord and/or Master Landlord within eight (8) business days following a request therefor.

  15.CONFIDENTIALITY.  For purposes of this Sublease, “Confidential Information” shall mean any information disclosed by one party to the other party in the performance hereunder or encountered by either party in connection with the use of the shared space, including, without limitation, methods of operation, customers, customer lists, products, prices, fees, costs, technology, inventions, trade secrets, know-how, software, marketing methods, plans, personnel, suppliers, competitors, markets or other specialized information or proprietary matters; provided, however, “Confidential Information” does not include, and there shall be no obligation hereunder with respect to, information that (a) is generally available to the public on the Effective Date, (b) becomes generally available to the public after the Effective Date other than as a result of a disclosure not otherwise permissible hereunder, (c) is acquired by the receiving party from third party sources not in breach of any confidentiality obligation of which the receiving party is aware and having the legal right to disclose same, or (d) is independently developed by the receiving party without use of or any reference to the confidential information of the disclosing party or other information obtained in dealings with the disclosing party; provided that none of the foregoing exclusions shall apply to Personally Identifiable Information which shall remain Confidential Information.  Each party shall and shall cause their respective affiliates and representatives to keep confidential this Sublease and all Confidential Information provided to it by or on behalf of the other party or otherwise obtained by it in connection with this Sublease and/or any of the transactions contemplated by it.  Notwithstanding the foregoing, neither party and its respective officers, directors, employees or affiliates shall have any obligation to keep confidential any Confidential Information if and to the extent disclosure thereof is specifically required by Applicable Laws; provided, however, that in the event disclosure is required by judicial or administrative process or by other requirements of Applicable Law, a party shall, to the extent reasonably possible and legally permissible, (x) provide the other party with prompt written notice of such requirement prior to making any disclosure so that such other party may seek an appropriate protective order and (y) disclose only that information that is required to be furnished. 

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  Upon written request of the disclosing party, the other party will promptly return to such disclosing party all of the written Confidential Information of such disclosing party, as well as all written material which incorporates any Confidential Information of such disclosing party, except that one (1) copy of the Confidential Information may be retained by the other party for archival purposes.  Each party acknowledges that the disclosure of Confidential Information without the disclosing party’s express written permission may cause such disclosing party irreparable harm and that the breach or threatened breach of this Section may entitle such disclosing party to injunctive relief, in addition to any other legal remedies that may be available to it.  All obligations of confidentiality and non-disclosure set forth in this Section 15 will survive the expiration or earlier termination of this Sublease for a period of five years.  As used herein, “Personally Identifiable Information” means any information that identifies, relates to, describes, is reasonably capable of being associated with, or could reasonably be linked, directly or indirectly, with a particular natural person or household (including any information related to the health of a person) and any information derived from the foregoing.

  16.Brokerage.  Subtenant warrants that it has not employed or dealt with any broker, agent or other finder that would be due any payment or commission in connection with the execution of this Sublease or occupancy of the Subleased Premises.  Sublandlord warrants that it has not employed or dealt with any broker, agent or other finder that would be due any payment or commission in connection with the execution of this Sublease or occupancy of the Subleased Premises.  Sublandlord and Subtenant shall indemnify and hold each other and Master Landlord harmless from any loss, claim or damage relating to the breach of the foregoing representation and warranty.  The provisions of this Section 16 shall survive the termination of this Sublease. 

  17.Security Deposit.  On or before the date that is thirty (30) days after the Effective Date, Subtenant shall provide a security deposit (the “Security Deposit”) in the form of a letter of credit in the amount of Six Hundred Seventy Thousand Six Hundred Nineteen and 73/100 Dollars ($670,619.73).  The Security Deposit shall be subject to all of the same terms and conditions of the Total Premises Security Deposit in the Master Lease, except that Sublandlord shall be the beneficiary of the letter of credit and there shall be no reduction during the Sublease Term.  There shall be no notice or cure period for failure to timely deliver the Security Deposit prior to such failure being a default of this Sublease.

  [signature page follows]

  19

  

   

  IN WITNESS WHEREOF, Sublandlord and Subtenant have executed this Sublease as of the Effective Date.

  		
	SUBLANDLORD:
 
ROADRUNNER SOLUTIONS LLC, 
a Delaware limited liability company
By: /s/ Tim Kelly	
Name:	Tim Kelly 
Title:	Chief Executive Officer
	SUBTENANT:
 
HOMOLOGY MEDICINES, INC., 
a Delaware corporation
By: /s/ Arthur O. Tzianabos	
Name:	Arthur O. Tzianabos
Title:	President and Chief Executive Officer

   

   

   

  [Schedule A]

   

  

   

  EXHIBIT A

  SUBLEASED PREMISES

   

   

   

  

   

  SCHEDULE A

  Payment for ServicesEX-10.13

  Exhibit 10.13

  Employment Agreement

  This Employment Agreement (this “Agreement”), dated as of March 18, 2020, is made by and between Homology Medicines, Inc., a Delaware corporation (together with any successor thereto, the “Company”), and Paul Alloway, PhD, J.D. (“Executive”) (collectively referred to herein as the “Parties” or individually referred to as a “Party”), and effective as of May 4, 2020 (the “Effective Date”).   

  RECITALS

  A.	It is the desire of the Company to assure itself of the services of Executive as of the Effective Date and thereafter by entering into this Agreement.

  B.	Executive and the Company mutually desire that Executive provide services to the Company on the terms herein provided. 

  AGREEMENT

  NOW, THEREFORE, in consideration of the foregoing and of the respective covenants and agreements set forth below, the Parties hereto agree as follows:

  1.Employment.

  (a)General.  Effective on the Effective Date, the Company shall employ Executive, and Executive shall be employed by the Company, for the period and in the positions set forth in this Section 1, and subject to the other terms and conditions herein provided.  

  (b)At-Will Employment.  The Company and Executive acknowledge that Executive’s employment is and shall continue to be at-will, as defined under applicable law, and that Executive’s employment with the Company may be terminated by either Party at any time for any or no reason (subject to the notice requirements of Section 3(b)).  This “at-will” nature of Executive’s employment shall remain unchanged during Executive’s tenure as an employee and may not be changed, except in an express writing signed by Executive and a duly authorized officer of the Company.  If Executive’s employment terminates for any reason, Executive shall not be entitled to any payments, benefits, damages, award or compensation other than as provided in this Agreement or otherwise agreed to in writing by the Company or as provided by applicable law.  The term of this Agreement (the “Term”) shall commence on the Effective Date and end on the date this Agreement is terminated under Section 3.

  (c)Positions and Duties.  During the Term, Executive shall serve as General Counsel of the Company, with such responsibilities, duties and authority normally associated with such position and as may from time to time be assigned to Executive by the Chief Executive Officer of the Company (the “Supervisor”).  Executive shall devote substantially all of Executive’s working time and efforts to the business and affairs of the Company (which shall include service to its affiliates, if applicable) and shall not engage in outside business activities (including serving on outside boards or committees) without the consent of the Board of Directors of the Company or an authorized committee of the Board (in either case, the “Board”), provided that Executive shall be permitted to (i) manage Executive’s personal, financial and legal affairs, (ii) participate in trade associations, and (iii) serve on the board of directors of not-for-profit or tax-exempt charitable organizations, in each case, subject to compliance with this 

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  Agreement and provided that such activities do not materially interfere with Executive’s performance of Executive’s duties and responsibilities hereunder.  Executive agrees to observe and comply with the rules and policies of the Company as adopted by the Company from time to time, in each case, as amended from time to time, and as delivered or made available to Executive (each, a “Policy”). 

  2.Compensation and Related Matters.

  (a)Annual Base Salary.  During the Term, Executive shall receive a base salary at a rate of $360,000.00 per annum, which shall be paid in accordance with the customary payroll practices of the Company and shall be pro-rated for partial years of employment.  Such annual base salary shall be reviewed (and may be adjusted) from time to time by the Board (such annual base salary, as it may be adjusted from time to time, the “Annual Base Salary”). 

  (b)Annual Cash Bonus Opportunity.  During the Term, Executive will be eligible to participate in an annual incentive program established by the Board.  Executive’s annual incentive compensation under such incentive program (the “Annual Bonus”) shall be targeted at 40% of Executive’s Annual Base Salary (such target, as may be increased by the Board from time to time, the “Target Annual Bonus”), provided that any Annual Bonus awarded to you for 2020 performance will be pro-rated based on the length of your employment during 2020.  The Annual Bonus payable under the incentive program shall be based on the achievement of performance goals to be determined by the Board.  The payment of any Annual Bonus pursuant to the incentive program shall be subject to Executive’s continued employment with the Company through the date of payment, except as otherwise provided in Section 4(b). 

  (c)Signing Bonus.  The Company agrees to pay you a one-time signing bonus of $35,000 (the “Signing Bonus”), payable upon the Company’s second regular payroll date following the Start Date and subject to all applicable tax reporting and withholding requirements. In the event you resign from the Company for any reason other than Good Reason (as defined below) or you are terminated by the Company for Cause (as defined below), in either case, within twelve (12) months after your Start Date, you will be responsible for reimbursing the Company the entire gross amount of the Signing Bonus. By signing this Agreement, you authorize the Company to withhold the amount of the Signing Bonus from any final pay, on an after-tax basis, that may be owed to you upon the termination of your employment in the event you are responsible for such reimbursement.

  (d)Benefits.  During the Term, Executive shall be eligible to participate in employee benefit plans, programs and arrangements of the Company (including medical, dental and 401(k) plans), subject to the terms and eligibility requirements thereof and as such plans, programs and arrangements may be amended from time to time.  In no event shall Executive be eligible to participate in any severance plan or program of the Company, except as set forth in Section 4 of this Agreement.

  (e)Vacation.  During the Term, Executive shall be entitled to paid personal leave in accordance with the Company’s Policies.  Any vacation shall be taken at the reasonable and mutual convenience of the Company and Executive. 

  (f)Business Expenses.  During the Term, the Company shall reimburse Executive for all reasonable travel and other business expenses incurred by Executive in the performance of Executive’s duties to the Company in accordance with the Company’s expense reimbursement Policy.

  (g)Key Person Insurance.  At any time during the Term, the Company shall have the right (but not the obligation) to insure the life of Executive for the Company’s sole benefit.  The Company shall 

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  |US-DOCS\123614162.2||

  

  have the right to determine the amount of insurance and the type of policy.  Executive shall reasonably cooperate with the Company in obtaining such insurance by submitting to physical examinations, by supplying all information reasonably required by any insurance carrier, and by executing all necessary documents reasonably required by any insurance carrier, provided that any information provided to an insurance company or broker shall not be provided to the Company without the prior written authorization of Executive.  Executive shall incur no financial obligation by executing any required document, and shall have no interest in any such policy.  

  3.Termination.

  Executive’s employment hereunder and the Term may be terminated by the Company or Executive, as applicable, without any breach of this Agreement under the following circumstances and the Term will end on the Date of Termination:

  (a)Circumstances.

  (i)Death.  Executive’s employment hereunder shall terminate upon Executive’s death.

  (ii)Disability.  If Executive has incurred a Disability, as defined below, the Company may terminate Executive’s employment.

  (iii)Termination for Cause.  The Company may terminate Executive’s employment for Cause, as defined below.

  (iv)Termination without Cause.  The Company may terminate Executive’s employment without Cause.

  (v)Resignation from the Company with Good Reason.  Executive may resign Executive’s employment with the Company with Good Reason, as defined below.

  (vi)Resignation from the Company without Good Reason.  Executive may resign Executive’s employment with the Company for any reason other than Good Reason or for no reason.

  (b)Notice of Termination.  Any termination of Executive’s employment by the Company or by Executive under this Section 3 (other than termination pursuant to Section 3(a)(i)) shall be communicated by a written notice to the other Party hereto (i) indicating the specific termination provision in this Agreement relied upon, (ii) setting forth in reasonable detail the facts and circumstances claimed to provide a basis for termination of Executive’s employment under the provision so indicated, if applicable, and (iii) specifying a Date of Termination which, if submitted by Executive, shall be at least thirty (30) days following the date of such notice (a “Notice of Termination”); provided, however, that in the event that Executive delivers a Notice of Termination to the Company, the Company may, in its sole discretion, change the Date of Termination to any date that occurs following the date of the Company’s receipt of such Notice of Termination and is prior to the date specified in such Notice of Termination, but the termination will still be considered a resignation by Executive.  A Notice of Termination submitted by the Company may provide for a Date of Termination on the date Executive receives the Notice of Termination, or any date thereafter elected by the Company.  The failure by either Party to set forth in the Notice of Termination any fact or circumstance which contributes to a showing of Cause or Good Reason shall not waive any right of the Party hereunder or preclude the Party from asserting such fact or circumstance in enforcing the Party’s rights hereunder.    

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  (c)Company Obligations upon Termination.  Upon termination of Executive’s employment pursuant to any of the circumstances listed in this Section 3, Executive (or Executive’s estate) shall be entitled to receive the sum of:  (i) the portion of Executive’s Annual Base Salary earned through the Date of Termination, but not yet paid to Executive; (ii) any expense reimbursements owed to Executive pursuant to Section 2(e); and (iii) any amount accrued and arising from Executive’s participation in, or benefits accrued under any employee benefit plans, programs or arrangements, which amounts shall be payable in accordance with the terms and conditions of such employee benefit plans, programs or arrangements (collectively, the “Company Arrangements”).  Except as otherwise expressly required by law (e.g., COBRA) or as specifically provided herein, all of Executive’s rights to salary, severance, benefits, bonuses and other compensatory amounts hereunder (if any) shall cease upon the termination of Executive’s employment hereunder. In the event that Executive’s employment is terminated by the Company for any reason, Executive’s sole and exclusive remedy shall be to receive the payments and benefits described in this Section 3(c) or Section 4, as applicable.  

  (d)Deemed Resignation.  Upon termination of Executive’s employment for any reason, Executive shall be deemed to have resigned from all offices and directorships, if any, then held with the Company or any of its subsidiaries.

  4.Severance Payments.

  (a)Termination for Cause, or Termination Upon Death, Disability or Resignation from the Company Without Good Reason.  If Executive’s employment shall terminate as a result of Executive’s death pursuant to Section 3(a)(i) or Disability pursuant to Section 3(a)(ii), pursuant to Section 3(a)(iii) for Cause, or pursuant to Section 3(a)(iv) for Executive’s resignation from the Company without Good Reason, then Executive shall not be entitled to any severance payments or benefits, except as provided in Section 3(c).

  (b)Termination without Cause, or Resignation from the Company with Good Reason.  If Executive’s employment terminates without Cause pursuant to Section 3(a)(iv), or pursuant to Section 3(a)(v) due to Executive’s resignation with Good Reason, then, subject to Executive signing on or before the 21st day following Executive’s Separation from Service (as defined below), and not revoking, a release of claims substantially in the form attached as Exhibit A to this Agreement (the “Release”),  and Executive’s continued compliance with Section 5, Executive shall receive, in addition to payments and benefits set forth in Section 3(c), the following:

  (i)an amount in cash equal to 0.75 times the Annual Base Salary, payable in the form of salary continuation in regular installments over the 9-month period following the date of Executive’s Separation from Service (the “Severance Period”) in accordance with the Company’s normal payroll practices;

  (ii)to the extent unpaid as of the Date of Termination, an amount of cash equal to any Annual Bonus earned by Executive for the Company’s fiscal year prior to the fiscal year in which the Date of Termination occurs, as determined by the Board in its discretion based upon actual performance achieved, which Annual Bonus, if any, shall be paid to Executive in the fiscal year in which the Date of Termination occurs when bonuses for such prior fiscal year are paid in the ordinary course to actively employed senior executives of the Company; and

  (iii)if Executive timely elects to receive continued medical, dental or vision coverage under one or more of the Company’s group medical, dental or vision plans pursuant to the Consolidated 

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  Omnibus Budget Reconciliation Act of 1985, as amended (“COBRA”), then the Company shall directly pay, or reimburse Executive for, the COBRA premiums for Executive and Executive’s covered dependents under such plans, less the amount Executive would have had to pay to receive such coverage as an active employee based on the cost sharing levels in effect on the Date of Termination, during the period commencing on Executive’s Separation from Service and ending upon the earliest of (X) the last day of the Severance Period, (Y) the date that Executive and/or Executive’s covered dependents become no longer eligible for COBRA or (Z) the date Executive becomes eligible to receive medical, dental or vision coverage, as applicable, from a subsequent employer (and Executive agrees to promptly notify the Company of such eligibility).  Notwithstanding the foregoing, if the Company determines in its sole discretion that it cannot provide the foregoing benefit without potentially violating applicable law (including, without limitation, Section 2716 of the Public Health Service Act) or incurring an excise tax, the Company shall in lieu thereof provide to Executive a taxable monthly payment in an amount equal to the monthly COBRA premium that Executive would be required to pay to continue Executive’s and Executive’s covered dependents’ group health coverage in effect on the Date of Termination (which amount shall be based on the premium for the first month of COBRA coverage), less the amount Executive would have had to pay to receive group health coverage as an active employee for Executive and his or her covered dependents based on the cost sharing levels in effect on the Date of Termination, which payments shall be made regardless of whether Executive elects COBRA continuation coverage and shall commence in the month following the month in which the Date of Termination occurs and shall end on the earliest of (X) the last day of the Severance Period, (Y) the date that Executive and/or Executive’s covered dependents become no longer eligible for COBRA or (Z) the date Executive becomes eligible to receive healthcare coverage from a subsequent employer (and Executive agrees to promptly notify the Company of such eligibility).

  (c)Change in Control.  In lieu of the payments and benefits set forth in Section 4(b), in the event Executive’s employment terminates without Cause pursuant to Section 3(a)(iv), or pursuant to Section 3(a)(v) due to Executive’s resignation with Good Reason, in either case, on or within twelve (12) months following the date of a Change in Control, subject to Executive signing on or before the 21st day following Executive’s Separation from Service, and not revoking, the Release, Executive shall receive, in addition to the payments and benefits set forth in Section 3(c), the following:

  (i)an amount in cash equal to the sum of (A) the Annual Base Salary plus (B) the Target Annual Bonus, payable in equal installments over the 12-month period following the date of Executive’s Separation from Service (the “CIC Severance Period”) in accordance with the Company’s normal payroll practices;

  (ii)the payment set forth in Section 4(b)(ii);

  (iii)the benefits set forth in Section 4(b)(iii), provided that the “Severance Period” will mean the CIC Severance Period; and

  (iv)all unvested equity or equity-based awards held by Executive under any Company equity compensation plans that vest solely based on the passage of time shall immediately become 100% vested (for the avoidance of doubt, with any such awards that vest in whole or in part based on the attainment of performance-vesting conditions being governed by the terms of the applicable award agreement).

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  (d)Survival.  Notwithstanding anything to the contrary in this Agreement, the provisions of Sections 5 through 9 will survive the termination of Executive’s employment and the termination of the Term.

  5.Restrictive Covenants.  As a condition to the effectiveness of this Agreement, Executive will have executed and delivered to the Company no later than contemporaneously herewith the Employee Proprietary Information and Inventions Assignment Agreement attached as Exhibit B (the “Restrictive Covenant Agreement”). Executive agrees to abide by the terms of the Restrictive Covenant Agreement, which are hereby incorporated by reference into this Agreement. Executive acknowledges that the provisions of the Restrictive Covenant Agreement will survive the termination of Executive’s employment and the termination of the Term for the periods set forth in the Restrictive Covenant Agreement.

  6.Assignment and Successors.

  The Company may assign its rights and obligations under this Agreement to any of its affiliates or to any successor to all or substantially all of the business or the assets of the Company (by merger or otherwise), and may assign or encumber this Agreement and its rights hereunder as security for indebtedness of the Company and its affiliates. This Agreement shall be binding upon and inure to the benefit of the Company, Executive and their respective successors, assigns, personnel and legal representatives, executors, administrators, heirs, distributees, devisees, and legatees, as applicable.  None of Executive’s rights or obligations may be assigned or transferred by Executive, other than Executive’s rights to payments hereunder, which may be transferred only by will or operation of law.  Notwithstanding the foregoing, Executive shall be entitled, to the extent permitted under applicable law and applicable Company Arrangements, to select and change a beneficiary or beneficiaries to receive compensation hereunder following Executive’s death by giving written notice thereof to the Company.  

  7.Certain Definitions.

  (a)Cause.  The Company shall have “Cause” to terminate Executive’s employment hereunder upon:

  (i)The Board’s reasonable, good faith determination that Executive has refused to (A) substantially perform the duties associated with Executive’s position with the Company or (B) carry out the reasonable and lawful instructions of the Board concerning duties or actions consistent with the Executive’s position with the Company; 

  (ii)Executive’s breach of a material provision of this Agreement that, to the extent capable of cure, has remained uncured for a period of thirty (30) days following written notice from the Company;

  (iii)Executive’s conviction, plea of no contest, plea of nolo contendere, or imposition of unadjudicated probation for any felony or crime involving moral turpitude; 

  (iv)Executive’s unlawful use (including being under the influence) or possession of illegal drugs on the Company’s (or any of its affiliate’s) premises or while performing Executive’s duties and responsibilities under this Agreement; or

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  (v)Executive’s commission of any act of fraud, embezzlement, misappropriation, willful misconduct, or breach of fiduciary duty against the Company or any of its affiliates. 

  (b)Change in Control.  “Change in Control” shall have the meaning set forth in the Homology Medicines, Inc. 2018 Incentive Award Plan. 

  (c)Code.  “Code” shall mean the Internal Revenue Code of 1986, as amended, and the regulations and guidance promulgated thereunder.

  (d)Date of Termination.  “Date of Termination” shall mean (i) if Executive’s employment is terminated by Executive’s death, the date of Executive’s death; or (ii) if Executive’s employment is terminated pursuant to Section 3(a)(ii) – (vi) either the date indicated in the Notice of Termination or the date specified by the Company pursuant to Section 3(b), whichever is earlier.

  (e)Disability.  “Disability” shall mean, at any time the Company or any of its affiliates sponsors a long-term disability plan for the Company’s employees, “disability” as defined in such long-term disability plan for the purpose of determining a participant’s eligibility for benefits, provided, however, if the long-term disability plan contains multiple definitions of disability, “Disability” shall refer to that definition of disability which, if Executive qualified for such disability benefits, would provide coverage for the longest period of time.  The determination of whether Executive has a Disability shall be made by the person or persons required to make disability determinations under the long-term disability plan.  At any time the Company does not sponsor a long-term disability plan for its employees, “Disability” shall mean Executive’s inability to perform, with or without reasonable accommodation, the essential functions of Executive’s positions hereunder for a total of three months during any six-month period as a result of incapacity due to mental or physical illness as determined by a physician selected by the Company or its insurers and acceptable to Executive or Executive’s legal representative, with such agreement as to acceptability not to be unreasonably withheld or delayed.  Any refusal by Executive to submit to a medical examination for the purpose of determining Disability shall be deemed to constitute conclusive evidence of Executive’s Disability. 

  (f)Good Reason.  For the sole purpose of determining Executive’s right to severance payments and benefits as described above, Executive’s resignation will be with “Good Reason” if Executive resigns within ninety (90) days after any of the following events, unless Executive consents in writing to the applicable event:  (i) a reduction in Executive’s Annual Base Salary or Target Annual Bonus, (ii) a material decrease in Executive’s authority or areas of responsibility as are commensurate with Executive’s title or position with the Company, (iii) the relocation of Executive’s primary office to a location more than twenty-five (25) miles from the Executive’s primary office as of the date of this Agreement or (iv) the Company’s breach of a material provision of this Agreement.  Notwithstanding the foregoing, no Good Reason will have occurred unless and until Executive has:  (a) provided the Company, within sixty (60) days of Executive’s knowledge of the occurrence of the facts and circumstances underlying the Good Reason event, written notice stating with specificity the applicable facts and circumstances underlying such finding of Good Reason; (b) provided the Company with an opportunity to cure the same within thirty (30) days after the receipt of such notice; and (c) the Company shall have failed to so cure within such period. 

  8.Parachute Payments.

  (a)Notwithstanding any other provisions of this Agreement or any Company equity plan or agreement, in the event that any payment or benefit by the Company or otherwise to or for the benefit of 

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  Executive, whether paid or payable or distributed or distributable pursuant to the terms of this Agreement or otherwise (all such payments and benefits, including the payments and benefits under Section 4 hereof, being hereinafter referred to as the “Total Payments”), would be subject (in whole or in part) to the excise tax imposed by Section 4999 of the Code (the “Excise Tax”), then the Total Payments shall be reduced (in the order provided in Section 8(b)) to the minimum extent necessary to avoid the imposition of the Excise Tax on the Total Payments, but only if (i) the net amount of such Total Payments, as so reduced (and after subtracting the net amount of federal, state and local income and employment taxes on such reduced Total Payments and after taking into account the phase out of itemized deductions and personal exemptions attributable to such reduced Total Payments), is greater than or equal to (ii) the net amount of such Total Payments without such reduction (but after subtracting the net amount of federal, state and local income and employment taxes on such Total Payments and the amount of the Excise Tax to which Executive would be subject in respect of such unreduced Total Payments and after taking into account the phase out of itemized deductions and personal exemptions attributable to such unreduced Total Payments).

  (b)The Total Payments shall be reduced in the following order:  (i) reduction on a pro-rata basis of any cash severance payments that are exempt from Section 409A of the Code (“Section 409A”), (ii) reduction on a pro-rata basis of any non-cash severance payments or benefits that are exempt from Section 409A, (iii) reduction on a pro-rata basis of any other payments or benefits that are exempt from Section 409A, and (iv) reduction of any payments or benefits otherwise payable to Executive on a pro-rata basis or such other manner that complies with Section 409A; provided, in case of clauses (ii), (iii) and (iv), that reduction of any payments attributable to the acceleration of vesting of Company equity awards shall be first applied to Company equity awards that would otherwise vest last in time.

  (c)All determinations regarding the application of this Section 8 shall be made by an accounting firm or consulting group with experience in performing calculations regarding the applicability of Section 280G of the Code and the Excise Tax selected by the Company (the “Independent Advisors”).  For purposes of determinations, no portion of the Total Payments shall be taken into account which, in the opinion of the Independent Advisors, (i) does not constitute a “parachute payment” within the meaning of Section 280G(b)(2) of the Code (including by reason of Section 280G(b)(4)(A) of the Code) or (ii) constitutes reasonable compensation for services actually rendered, within the meaning of Section 280G(b)(4)(B) of the Code, in excess of the “base amount” (as defined in Section 280G(b)(3) of the Code) allocable to such reasonable compensation.  The costs of obtaining such determination and all related fees and expenses (including related fees and expenses incurred in any later audit) shall be borne by the Company.

  (d)In the event it is later determined that a greater reduction in the Total Payments should have been made to implement the objective and intent of this Section 8, the excess amount shall be returned promptly by Executive to the Company. 

  9.Miscellaneous Provisions.

  (a)Governing Law.  This Agreement shall be governed, construed, interpreted and enforced in accordance with its express terms, and otherwise in accordance with the substantive laws of the Commonwealth of Massachusetts without reference to the principles of conflicts of law of the Commonwealth of Massachusetts or any other jurisdiction that would result in the application of the laws of a jurisdiction other than the Commonwealth of Massachusetts, and where applicable, the laws of the United States.  

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  (b)Validity.  The invalidity or unenforceability of any provision or provisions of this Agreement shall not affect the validity or enforceability of any other provision of this Agreement, which shall remain in full force and effect.  

  (c)Notices.  Any notice, request, claim, demand, document and other communication hereunder to any Party shall be effective upon receipt (or refusal of receipt) and shall be in writing and delivered personally or sent by facsimile or certified or registered mail, postage prepaid, as follows:

  (i)If to the Company, to the Chief Executive Officer of the Company at the Company’s headquarters,

  (ii)If to Executive, to the last address that the Company has in its personnel records for Executive, or

  (iii)At any other address as any Party shall have specified by notice in writing to the other Party.

  (d)Counterparts.  This Agreement may be executed in several counterparts, each of which shall be deemed to be an original, but all of which together will constitute one and the same Agreement.  Signatures delivered by facsimile or PDF shall be deemed effective for all purposes.

  (e)Entire Agreement.  The terms of this Agreement, and the Restrictive Covenant Agreement incorporated herein by reference as set forth in Section 5, are intended by the Parties to be the final expression of their agreement with respect to the subject matter hereof and supersede all prior understandings and agreements, whether written or oral, including, any prior employment offer letter or employment agreement between Executive and the Company.  The Parties further intend that this Agreement shall constitute the complete and exclusive statement of their terms and that no extrinsic evidence whatsoever may be introduced in any judicial, administrative, or other legal proceeding to vary the terms of this Agreement. 

  (f)Amendments; Waivers.  This Agreement may not be modified, amended, or terminated except by an instrument in writing, signed by Executive and a duly authorized officer of Company.  By an instrument in writing similarly executed, Executive or a duly authorized officer of the Company may waive compliance by the other Party with any specifically identified provision of this Agreement that such other Party was or is obligated to comply with or perform; provided, however, that such waiver shall not operate as a waiver of, or estoppel with respect to, any other or subsequent failure.  No failure to exercise and no delay in exercising any right, remedy, or power hereunder will preclude any other or further exercise of any other right, remedy, or power provided herein or by law or in equity.  

  (g)Construction.  This Agreement shall be deemed drafted equally by both the Parties. Its language shall be construed as a whole and according to its fair meaning.  Any presumption or principle that the language is to be construed against any Party shall not apply.  The headings in this Agreement are only for convenience and are not intended to affect construction or interpretation.  Any references to paragraphs, subparagraphs, sections or subsections are to those parts of this Agreement, unless the context clearly indicates to the contrary.  Also, unless the context clearly indicates to the contrary, (i) the plural includes the singular and the singular includes the plural; (ii) “and” and “or” are each used both conjunctively and disjunctively; (iii) “any,” “all,” “each,” or “every” means “any and all,” and “each and every”; (iv) “includes” and “including” are each “without limitation”; (v) “herein,” “hereof,” “hereunder” and other similar compounds of the word “here” refer to the entire Agreement and not to any particular 

  	9

   

  |US-DOCS\123614162.2||

  

  paragraph, subparagraph, section or subsection; and (vi) all pronouns and any variations thereof shall be deemed to refer to the masculine, feminine, neuter, singular or plural as the identity of the entities or persons referred to may require. 

  (h)Arbitration.  Any controversy, claim or dispute arising out of or relating to this Agreement, shall be settled solely and exclusively by a binding arbitration process administered by JAMS/Endispute in Boston, Massachusetts.  Such arbitration shall be conducted in accordance with the then-existing JAMS/Endispute Rules of Practice and Procedure, with the following exceptions if in conflict:  (i) one arbitrator who is a retired judge shall be chosen by JAMS/Endispute; (ii) each Party to the arbitration will pay one-half of the expenses and fees of the arbitrator, together with other expenses of the arbitration incurred or approved by the arbitrator; and (iii) arbitration may proceed in the absence of any Party if written notice (pursuant to the JAMS/Endispute rules and regulations) of the proceedings has been given to such Party.  Each Party shall bear its own attorney’s fees and expenses; provided that the arbitrator may assess the prevailing Party’s fees and costs against the non-prevailing Party as part of the arbitrator’s award.  The Parties agree to abide by all decisions and awards rendered in such proceedings.  Such decisions and awards rendered by the arbitrator shall be final and conclusive.  All such controversies, claims or disputes shall be settled in this manner in lieu of any action at law or equity; provided, however, that nothing in this subsection shall be construed as precluding the bringing of an action for injunctive relief or specific performance as provided in this Agreement or the Restrictive Covenant Agreement.  This dispute resolution process and any arbitration hereunder shall be confidential and neither any Party nor the neutral arbitrator shall disclose the existence, contents or results of such process without the prior written consent of all Parties, except where necessary or compelled in a court to enforce this arbitration provision or an award from such arbitration or otherwise in a legal proceeding.  If JAMS/Endispute no longer exists or is otherwise unavailable, the Parties agree that the American Arbitration Association (“AAA”) shall administer the arbitration in accordance with its then-existing rules as modified by this subsection.  In such event, all references herein to JAMS/Endispute shall mean AAA.  Notwithstanding the foregoing, Executive and the Company each have the right to resolve any issue or dispute over intellectual property rights by court action instead of arbitration.

  (i)Enforcement.  If any provision of this Agreement is held to be illegal, invalid or unenforceable under present or future laws effective during the Term, such provision shall be fully severable; this Agreement shall be construed and enforced as if such illegal, invalid or unenforceable provision had never comprised a portion of this Agreement; and the remaining provisions of this Agreement shall remain in full force and effect and shall not be affected by the illegal, invalid or unenforceable provision or by its severance from this Agreement.  Furthermore, in lieu of such illegal, invalid or unenforceable provision there shall be added automatically as part of this Agreement a provision as similar in terms to such illegal, invalid or unenforceable provision as may be possible and be legal, valid and enforceable.

  (j)Withholding.  The Company shall be entitled to withhold from any amounts payable under this Agreement any federal, state, local or foreign withholding or other taxes or charges which the Company is required to withhold. The Company shall be entitled to rely on the advice of counsel if any questions as to the amount or requirement of withholding shall arise.

  (k)Section 409A.

  (i)General.  The intent of the Parties is that the payments and benefits under this Agreement comply with or be exempt from Section 409A and, accordingly, to the maximum extent permitted, this Agreement shall be interpreted to be in compliance therewith.  

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  (ii)Separation from Service.  Notwithstanding anything in this Agreement to the contrary, any compensation or benefits payable under this Agreement that is designated under this Agreement as payable upon Executive’s termination of employment shall be payable only upon Executive’s “separation from service” with the Company within the meaning of Section 409A (a “Separation from Service”) and, except as provided below, any such compensation or benefits described in Section  shall not be paid, or, in the case of installments, shall not commence payment, until the thirtieth (30th) day following Executive’s Separation from Service (the “First Payment Date”).  Any installment payments that would have been made to Executive during the thirty (30) day period immediately following Executive’s Separation from Service but for the preceding sentence shall be paid to Executive on the First Payment Date and the remaining payments shall be made as provided in this Agreement.

  (iii)Specified Employee.  Notwithstanding anything in this Agreement to the contrary, if Executive is deemed by the Company at the time of Executive’s Separation from Service to be a “specified employee” for purposes of Section 409A, to the extent delayed commencement of any portion of the benefits to which Executive is entitled under this Agreement is required in order to avoid a prohibited distribution under Section 409A, such portion of Executive’s benefits shall not be provided to Executive prior to the earlier of (i) the expiration of the six-month period measured from the date of Executive’s Separation from Service with the Company or (ii) the date of Executive’s death.  Upon the first business day following the expiration of the applicable Section 409A period, all payments deferred pursuant to the preceding sentence shall be paid in a lump sum to Executive (or Executive’s estate or beneficiaries), and any remaining payments due to Executive under this Agreement shall be paid as otherwise provided herein.  

  (iv)Expense Reimbursements.  To the extent that any reimbursements under this Agreement are subject to Section 409A, any such reimbursements payable to Executive shall be paid to Executive no later than December 31 of the year following the year in which the expense was incurred; provided that Executive submits Executive’s reimbursement request promptly following the date the expense is incurred, the amount of expenses reimbursed in one year shall not affect the amount eligible for reimbursement in any subsequent year, other than medical expenses referred to in Section 105(b) of the Code, and Executive’s right to reimbursement under this Agreement will not be subject to liquidation or exchange for another benefit.

  (v)Installments.  Executive’s right to receive any installment payments under this Agreement, including without limitation any continuation salary payments that are payable on Company payroll dates, shall be treated as a right to receive a series of separate payments and, accordingly, each such installment payment shall at all times be considered a separate and distinct payment as permitted under Section 409A.  Except as otherwise permitted under Section 409A, no payment hereunder shall be accelerated or deferred unless such acceleration or deferral would not result in additional tax or interest pursuant to Section 409A.

  10.Executive Acknowledgement.

  Executive acknowledges that Executive has read and understands this Agreement, is fully aware of its legal effect, has not acted in reliance upon any representations or promises made by the Company other than those contained in writing herein, and has entered into this Agreement freely based on Executive’s own judgment.

  [Signature Page Follows]

   

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  IN WITNESS WHEREOF, the Parties have executed this Agreement on the date and year first above written.			

  				HOMOLOGY MEDICINES, INC.

  By:       /s/ Paul Alloway		

  Name:  Paul Alloway

  Title:    General Counsel

   

   

  				EXECUTIVE

     

  /s/ Arthur Tzianabos			

  Arthur Tzianabos, President and CEO

  	[Signature Page to Employment Agreement]

   

  |US-DOCS\123614162.2||

  

   

  EXHIBIT A

  Separation Agreement and Release

  	This Separation Agreement and Release (“Agreement”) is made by and between _______________(“Executive”) and Homology Medicines, Inc. (the “Company”) (collectively referred to as the “Parties” or individually referred to as a “Party”).  Capitalized terms used but not defined in this Agreement shall have the meanings set forth in the Employment Agreement (as defined below).

  	WHEREAS, the Parties have previously entered into that certain Employment Agreement, dated as of ________, 2019 (the “Employment Agreement”) and that certain Employee Proprietary Information and Inventions Assignment Agreement, dated as of ________, 2020 (the “Restrictive Covenant Agreement”); and 

  	WHEREAS, in connection with Executive’s termination of employment with the Company or a subsidiary or affiliate of the Company effective ________, 2020, the Parties wish to resolve any and all disputes, claims, complaints, grievances, charges, actions, petitions, and demands that Executive may have against the Company and any of the Releasees as defined below, including, but not limited to, any and all claims arising out of or in any way related to Executive’s employment with or separation from the Company or its subsidiaries or affiliates but, for the avoidance of doubt, nothing herein will be deemed to release any rights or remedies in connection with Executive’s ownership of vested equity securities of the Company, vested benefits or Executive’s right to indemnification by the Company or any of its affiliates pursuant to contract or applicable law (collectively, the “Retained Claims”).   

  	NOW, THEREFORE, in consideration of the severance payments and benefits described in Section 4 of the Employment Agreement, which, pursuant to the Employment Agreement, are conditioned on Executive’s execution and non-revocation of this Agreement, and in consideration of the mutual promises made herein, the Company and Executive hereby agree as follows:

  	1.	Severance Payments and Benefits; Salary and Benefits.  The Company agrees to provide Executive with the severance payments and benefits described in Section [4(b)/4(c)] of the Employment Agreement, payable at the times set forth in, and subject to the terms and conditions of, the Employment Agreement. In addition, to the extent not already paid, and subject to the terms and conditions of the Employment Agreement, the Company shall pay or provide to Executive all other payments or benefits described in Section 3(c) of the Employment Agreement, subject to and in accordance with the terms thereof.

  	2.	Release of Claims.  Executive agrees that, other than with respect to the Retained Claims, the foregoing consideration represents settlement in full of all outstanding obligations owed to Executive by the Company, any of its direct or indirect subsidiaries and affiliates, and any of its or their current and former officers, directors, equityholders, managers, employees, agents, investors, attorneys, shareholders, administrators, affiliates, benefit plans, plan administrators, insurers, trustees, divisions, and subsidiaries and predecessor and successor corporations and assigns (collectively, the “Releasees”).  Executive, on Executive’s own behalf and on behalf of any of Executive’s affiliated companies or entities and any of their respective heirs, family members, executors, agents, and assigns, other than with respect to the Retained Claims, hereby and forever releases the Releasees from, and agrees not to sue concerning, or in any manner to institute, prosecute, or pursue, any claim, complaint, charge, duty, obligation, or cause of action relating to any matters of any kind, whether presently known or unknown, suspected or unsuspected, that Executive may possess against any of the Releasees arising from any omissions, acts, 

   

   

  |US-DOCS\123614162.2||

  

   

  facts, or damages that have occurred up until and including the date Executive signs this Agreement, including, without limitation:

  		(a)	any and all claims relating to or arising from Executive’s employment or service relationship with the Company or any of its direct or indirect subsidiaries or affiliates and the termination of that relationship;

  		(b)	any and all claims relating to, or arising from, Executive’s right to purchase, or actual purchase of any shares of stock or other equity interests of the Company or any of its affiliates, including, without limitation, any claims for fraud, misrepresentation, breach of fiduciary duty, breach of duty under applicable state law, and securities fraud under any state or federal law;

  		(c)	any and all claims for wrongful discharge of employment; termination in violation of public policy; discrimination; harassment; retaliation; breach of contract, both express and implied; breach of covenant of good faith and fair dealing, both express and implied; promissory estoppel; negligent or intentional infliction of emotional distress; fraud; negligent or intentional misrepresentation; negligent or intentional interference with contract or prospective economic advantage; unfair business practices; defamation; libel; slander; negligence; personal injury; assault; battery; invasion of privacy; false imprisonment; conversion; and disability benefits;

  		(d)	any and all claims for violation of any federal, state, or municipal statute, including, but not limited to, Title VII of the Civil Rights Act of 1964; the Civil Rights Act of 1991; the Rehabilitation Act of 1973; the Americans with Disabilities Act of 1990; the Equal Pay Act; the Fair Labor Standards Act; the Fair Credit Reporting Act; the Age Discrimination in Employment Act of 1967; the Older Workers Benefit Protection Act; the Employee Retirement Income Security Act of 1974; the Worker Adjustment and Retraining Notification Act; the Family and Medical Leave Act; and the Sarbanes-Oxley Act of 2002;

  		(e)	any and all claims for violation of the federal or any state constitution;

  		(f) 	any and all claims arising out of any other laws and regulations relating to employment or employment discrimination;

  		(g)	any claim for any loss, cost, damage, or expense arising out of any dispute over the non-withholding or other tax treatment of any of the proceeds received by Executive as a result of this Agreement; 

  		(h)	any and all claims arising out of the wage and hour and wage payments laws and regulations of the state or states in which Executive has provided service to the Company or any of its affiliates (including without limitation the Massachusetts Payment of Wages Law); and

  		(i)	any and all claims for attorneys’ fees and costs.

  Executive agrees that the release set forth in this section shall be and remain in effect in all respects as a complete general release as to the matters released.  This release does not release claims that cannot be released as a matter of law, including, but not limited to, Executive’s right to report possible violations of federal law or regulation to any governmental agency or entity in accordance with the provisions of and rules promulgated under Section 21F of the Securities Exchange Act of 1934 or Section 806 of the 

  	A-2

   

  |US-DOCS\123614162.2||

  

   

  Sarbanes-Oxley Act of 2002, or any other whistleblower protection provisions of state or federal law or regulation and any right to receive an award for information provided thereunder, Executive’s right to file a charge with or participate in a charge by the Equal Employment Opportunity Commission, or any other local, state, or federal administrative body or government agency that is authorized to enforce or administer laws related to employment, against the Company for discrimination (with the understanding that Executive’s release of claims herein bars Executive from recovering such monetary relief from the Company or any Releasee for any alleged discriminatory treatment), claims for unemployment compensation or any state disability insurance benefits pursuant to the terms of applicable state law, claims to continued participation in certain of the Company’s group benefit plans pursuant to the terms and conditions of COBRA, claims to any benefit entitlements vested as the date of separation of Executive’s employment, pursuant to written terms of any employee benefit plan of the Company or its affiliates and Executive’s right under applicable law and any Retained Claims.  This release further does not release claims for breach of Section 3(c) or Section 4 of the Employment Agreement.

  	3.	Acknowledgment of Waiver of Claims under ADEA.  Executive understands and acknowledges that Executive is waiving and releasing any rights Executive may have under the Age Discrimination in Employment Act of 1967 (“ADEA”), and that this waiver and release is knowing and voluntary.  Executive understands and agrees that this waiver and release does not apply to any rights or claims that may arise under the ADEA after the date Executive signs this Agreement.  Executive understands and acknowledges that the consideration given for this waiver and release is in addition to anything of value to which Executive was already entitled.  Executive further understands and acknowledges that Executive has been advised by this writing that:  (a) Executive should consult with an attorney prior to executing this Agreement; (b) Executive has 21 days within which to consider this Agreement, and the Parties agree that such time period to review this Agreement shall not be extended upon any material or immaterial changes to this Agreement; (c) Executive has 7 days following Executive’s execution of this Agreement to revoke this Agreement pursuant to written notice to the General Counsel of the Company; (d) this Agreement shall not be effective until after the revocation period has expired; and (e) nothing in this Agreement prevents or precludes Executive from challenging or seeking a determination in good faith of the validity of this waiver under the ADEA, nor does it impose any condition precedent, penalties, or costs for doing so, unless specifically authorized by federal law.  In the event Executive signs this Agreement and returns it to the Company in less than the 21 day period identified above, Executive hereby acknowledges that Executive has freely and voluntarily chosen to waive the time period allotted for considering this Agreement.

  	4.	Restrictive Covenants.

  		(a) 	Executive acknowledges and agrees that the restrictive covenants and other post-termination obligations set forth in the Restrictive Covenant Agreement, including without limitation Executive’s obligations relating to confidentiality, non-use and non-disclosure of Proprietary Information (as defined in the Restrictive Covenant Agreement), non-solicitation, cooperation, and return of property, are hereby incorporated by reference and shall remain in full force and effect pursuant to their terms to the maximum extent permitted by applicable law, except that the Parties expressly agree to modify the Restrictive Covenant Agreement by removing Section 6.1, and each subpart thereto, of the Restrictive Covenant Agreement, which shall be of no further force or effect upon the Effective Date (as defined below). Executive represents and warrants that Executive has complied with all provisions of the Restrictive Covenant Agreement at all times through the Effective Date.

  	A-3

   

  |US-DOCS\123614162.2||

  

   

  		(b)	In consideration for the severance payments and benefits set forth in Section 1 of this Agreement, Executive agrees for a period of one year after the Effective Date (the “Non-Competition Restricted Period”) to not, directly or indirectly, on Executive’s own behalf or for the benefit of any other individual or entity other than the Company: (i) operate, conduct, or engage in, or prepare to operate, conduct, or engage in the Business (as defined below); (ii) own, finance, or invest in (except as the holder of not more than one percent of the outstanding stock of a publicly-held company) any Business; or (iii) participate in, render services to, or assist any person or entity that engages in or is preparing to engage in the Business in any capacity (whether as an employee, consultant, contractor, partner, officer, director, or otherwise) (x) which involves the same or similar types of services Executive performed for the Company at any time during the last two years of Executive’s employment with the Company or (y) in which Executive could reasonably be expected to use or disclose Proprietary Information, in each case (i), (ii) or (iii) in the Restricted Territory (as defined below). Without limiting the Company’s ability to seek other remedies available in law or equity, if Executive violates this Section 4(b), the Non-Competition Restricted Period shall be extended by one day for each day that Executive is in violation of such provisions, up to a maximum extension equal to the length of the Non-Competition Restricted Period, so as to give the Company the full benefit of the bargained-for length of forbearance.

  		(c)	Executive’s continued compliance with the terms of the Restrictive Covenant Agreement (as modified in Section 4(a) above) and the noncompetition obligations set forth in Section 4(b) above (collectively, the “Restrictive Covenants”) is a material condition to receipt of the severance payments and benefits set forth in Section 1 of this Agreement. In the event Executive breaches any part of such Restrictive Covenants, then, in addition to any remedies and enforcement mechanisms set forth in the Restrictive Covenant Agreement, the Employment Agreement and this Agreement, and any other remedies available to the Company (including equitable and injunctive remedies), Executive shall forfeit any additional consideration owing and shall be obligated to promptly return to the Company (within fifteen (15) business days of any breach) the full gross amount of all severance payments and benefits provided.

  		(d)	If any provision of the Restrictive Covenants shall be determined to be unenforceable by any court of competent jurisdiction or arbitrator by reason of its extending for too great a period of time or over too large a geographic area or over too great a range of activities, it shall be interpreted to extend only over the maximum period of time, geographic area or range of activities as to which it may be enforceable.

  		(e)	As used in this Agreement:

  			(i) 	The term “Business” means any business or part thereof that develops, manufactures, markets, licenses, sells or provides any product or service that competes with any product or service developed, manufactured, marketed, licensed, sold or provided, or planned to be developed, manufactured, marketed, licensed, sold or provided, by the Company, in each case at any time during Executive’s employment or engagement with the Company.

  			(ii)	The term “Restricted Territory” means each city, county, state, territory and country in which (i) Executive provided services or had a material presence or influence at any time during the last two years of Executive’s employment or engagement with the Company or (ii) the Company is engaged in or has plans to engage in the Business as of the termination of Executive’s employment or engagement with the Company.

  	A-4

   

  |US-DOCS\123614162.2||

  

   

  	5.	Severability.  In the event that any provision or any portion of any provision hereof or any surviving agreement made a part hereof becomes or is declared by a court of competent jurisdiction or arbitrator to be illegal, unenforceable, or void, this Agreement shall continue in full force and effect without said provision or portion of provision.

  	6.	No Oral Modification.  This Agreement may only be amended in a writing signed by Executive and a duly authorized officer of the Company.

  	7.	Governing Law; Notices; Dispute Resolution.  This Agreement shall be subject to the provisions of Sections 9(a), 9(c), and 9(h) of the Employment Agreement.

  	8.	Effective Date.  If Executive has attained or is over the age of 40 as of the date of Executive’s termination of employment, then each Party has seven days after that Party signs this Agreement to revoke it and this Agreement will become effective on the eighth day after Executive signed this Agreement (the “Effective Date”), so long as it has been signed by the Parties and has not been revoked by either Party before that date. If Executive has not attained the age of 40 as of the date of Executive’s termination of employment, then the “Effective Date” shall be the date on which Executive signs this Agreement. For the avoidance of doubt, if Executive revokes this Agreement as provided herein, the Parties’ modification to the Restrictive Covenant Agreement set forth in Section 4(a) above shall be void and of no effect and, unless the Company has elected or elects in writing to expressly waive Executive’s noncompetition obligations set forth in Section 6.1(a) of the Restrictive Covenant Agreement as provided in Section 6.6 of the Restrictive Covenant Agreement, the Restrictive Covenant Agreement, including without limitation Section 6.1 of the Restrictive Covenant Agreement, shall remain in full force and effect.

  	9.	Voluntary Execution of Agreement.  Executive understands and agrees that Executive executed this Agreement voluntarily, without any duress or undue influence on the part or behalf of the Company or any third party, with the full intent of releasing all of Executive’s claims against the Company and any of the other Releasees.  Executive acknowledges that:  (a) Executive has read this Agreement; (b) Executive has not relied upon any representations or statements made by the Company that are not specifically set forth in this Agreement; (c) Executive has been represented in the preparation, negotiation, and execution of this Agreement by legal counsel of Executive’s own choice or has elected not to retain legal counsel; (d) Executive understands the terms and consequences of this Agreement and of the releases it contains; and (e) Executive is fully aware of the legal and binding effect of this Agreement.	

  	IN WITNESS WHEREOF, the Parties have executed this Agreement on the respective dates set forth below.  

  	A-5

   

  |US-DOCS\123614162.2||

  

   

  		
	 
 
	EXECUTIVE

	Dated: 
						
[                        ]

	 
	 

	 
	HOMOLOGY MEDICINES, INC.

	Dated:
	By:						
Name:
Title:

   

   

  	A-6

   

  |US-DOCS\123614162.2||

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