Document:

novn-ex104_451.htm

 

Exhibit 10.4

SECOND AMENDMENT TO AMENDED, RESTATED AND CONSOLIDATED LICENSE AGREEMENT

This second amendment (the “Second Amendment”) to the Amended, Restated and Consolidated License Agreement dated June 27th, 2012 by and between The University of North Carolina at Chapel Hill (“University”) and Novan, Inc. (“Licensee”), as amended by the First Amendment to Amended, Restated and Consolidated License Agreement dated November 30, 2012 (hereinafter referred to as the “Agreement”), is effective as of April 12, 2016.

WHEREAS, the parties now wish to amend the Agreement to update Appendix A of the Agreement to include the Improvement known as [***] as a University Invention and;

WHEREAS, the parties agree to be bound by the terms and conditions of the Agreement, as amended herein;

NOW THEREFORE, the parties agree as follows:

	
 
	
1.
	
The following Improvement is deemed to be included in the University Inventions, and all patents and/or patent applications claiming such Improvement are deemed to be included in the Patent Rights for all purposes under the Agreement, including but not limited to the license granted to Licensee and Its Affiliates pursuant to Section 2.2 of the Agreement:

	
 
	
•
	
[***]

	
 
	
2.
	
Appendix A of the Agreement is hereby deleted in the entirety and replaced with the attached Appendix A.

	
 
	
3.
	
Capitalized terms used herein have the same meaning as was given them in the Agreement.

	
 
	
4.
	
Other than as amended herein, the Agreement remains in full force and effect.

	
 
	
5.
	
This Second Amendment may be executed by one or more of the parties to this Second Amendment on any number of separate counterparts (including by facsimile transmission or PDF signature), and all of said counterparts taken together shall be deemed to constitute one and the same instrument.

[Signatures appear on following page]

 

 

 

[***]  Confidential treatment requested pursuant to a request for confidential treatment filed with the Securities and Exchange Commission. Omitted portions have been filed separately with the Commission.

 

IN WITNESS WHEREOF, the parties have executed this Second Amendment to the Agreement, as indicated below.

 

	
THE UNIVERSITY OF NORTH

CAROLINA AT CHAPEL HILL
	
 
	
NOVAN INC.

	
 
	
 
	
 

	
/s/ Jacqueline Quay
	
 
	
/s/ Emily K. Hales

	
Jacqueline Quay
	
 
	
Name: Emily K. Hales

	
Director of Licensing, 

Office of Commercialization 

and Economic Development
	
 
	
Title: Corporate Counsel

	
 
	
 
	
 

	
4/22/16
	
 
	
5/6/16

	
Date
	
 
	
Date

	
 
	
 
	
 

	
Acknowledged and Agreed:
	
 
	
 

	
 
	
 
	
 

	
INVENTORS
	
 
	
 

	
 
	
 
	
 

	
/s/ Mark Schoenfisch
	
 
	
 

	
Mark Schoenfisch
	
 
	
 

	
 
	
 
	
 

	
/s/ Robert Soto
	
 
	
 

	
Robert Soto 
	
 
	
 

 

 

 

2

 

APPENDIX A 

Patent Rights

University Invention

[***]

[***]  Confidential treatment requested pursuant to a request for confidential treatment filed with the Securities and Exchange Commission. Omitted portions have been filed separately with the Commission.novn-ex105_450.htm

 

Exhibit 10.5

THIRD AMENDMENT TO LEASE AGREEMENT

THIS THIRD AMENDMENT TO LEASE AGREEMENT (this “Agreement”) is made and entered into as of the 5th day of July, 2016, by and between DURHAM ROYAL CENTER, LLC, a Delaware limited liability company (“Landlord”) and NOVAN, INC., a Delaware corporation (“Tenant”).

STATEMENT OF PURPOSE

WHEREAS, Landlord’s predecessor in title and Tenant entered into a Lease Agreement dated as of December 21, 2010 as amended by that First Amendment to Lease Agreement dated August 27, 2013, and as amended by that Second Amendment to Lease Agreement (the “Second Amendment”) dated August 27, 2015 (collectively, the “Lease”) for certain premises containing approximately nineteen thousand three hundred sixty-seven (19,367) rentable square feet of space located at Suite 470 in the building known as Royal Center I and Suite 200 in the building known as Royal Center II both of which are located at 4222 Emperor Boulevard, Durham, North Carolina, as more particularly described in the Lease (the “Premises”). The Premises consists of Suite 470 of containing 12,147 rentable square feet (“Suite 470”) and Suite 200 containing 7,220 rentable square feet (“Suite 200”).

WHEREAS, Landlord and Tenant previously entered into the Second Amendment to terminate the term of lease for both Suite 470 and Suite 200 earlier than as stated in the Lease;

WHEREAS, Landlord and Tenant now desire to revise the termination dates for Suite 470 and Suite 200 as stated herein and to otherwise amend the Lease as hereinafter provided.

NOW, THEREFORE, in consideration of the statement of purpose, the mutual covenants contained herein and other valuable consideration, the receipt of which is hereby acknowledged, the parties hereto agree as follows:

1. Termination of Lease. (a) Notwithstanding anything contained in the Second Amendment, Landlord and Tenant hereby agree that Tenant’s lease of Suite 470 shall continue until December 31, 2016 (the “Suite 470 Termination Date”). On the Suite 470 Termination Date, Tenant shall surrender Suite 470 to Landlord in the condition described in Section 1 of the Second Amendment. Tenant shall pay Minimum Rent for Suite 470 in accordance with Section 2 below.

(b) Notwithstanding anything contained in the Second Amendment, Landlord and Tenant hereby agree that Tenant’s lease of Suite 200 shall continue until October 31, 2016 (the “Suite 200 Termination Date”). On the Suite 200 Termination Date Tenant, shall surrender Suite 200 to Landlord in the condition described in Section 1 of the Second Amendment. Tenant shall pay Minimum Rent for Suite 200 in accordance with Section 2 below.

2. Minimum Rent. Tenant shall pay Minimum Rent for Suite 470 and Suite 200 according to the following schedules and otherwise in the manner provided for in the Lease:

Suite 470 Minimum Rent

 

	
 
	
Minimum Rental per
	
Monthly

	
Period
	
rentable square foot (yearly)
	
Minimum Rental

	
09/01/2016 – 12/31/2016
	
$17.06
	
$17,268.99

 

RA-3181734 v4

 

Suite 200 Minimum Rent

 

	
 
	
Minimum Rental per
	
Monthly

	
Period
	
rentable square foot (yearly)
	
Minimum Rental

	
09/01/2016 – 10/31/2016
	
$13.47
	
$8,104.45

3. Tenant’s Share of Expenses. Tenant shall continue to pay Tenant’s Proportionate Share of the Operating Expenses for the Premises in accordance with the Lease including any reconciliation after the applicable termination date for each suite.

4. Representations and Warranties of Tenant. Tenant owns the entire leasehold interest granted by the Lease and has not assigned its leasehold interest, subleased the Premises nor granted a security interest in its leasehold interest that is the subject of the Lease and Tenant certifies that there are no tenants or other persons or entities having a right to possession of the Premises or any portion thereof after Tenant vacates the Premises. On or before the Termination Date, if applicable, Tenant shall satisfy, or obtain releases of, all outstanding liens or financing statements encumbering Tenant’s leasehold interest in the Premises.

5. Broker. Notwithstanding anything contained herein to the contrary, in no event shall any broker receive any compensation or commission relative to this Agreement.

6. Expenses. In the event that Tenant defaults under any of its obligations set forth above, Landlord shall be entitled to employ all rights and remedies available to it for enforcement of such obligations, and Tenant shall be responsible for paying any and all costs and expenses of the Landlord, including reasonable attorneys’ fees in enforcing the obligations of Tenant hereunder.

7. Benefits and Binding Effect. This Agreement shall be binding upon and shall inure to the benefit of the parties hereto and their respective successors and assigns.

8. Counterparts. This Agreement may be executed in one or more counterparts, each of which shall be deemed an original hereof, and all of which shall be considered one and the same instrument.

 

IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be duly executed pursuant to authority duly given as of the day and year first above written.

 

	
 
	
“LANDLORD”

	
 
	
 

	
 
	
DURHAM ROYAL CENTER, LLC,

	
 
	
a Delaware limited liability company

	
 
	
 
	
 

	
 
	
By:
	
/s/ Jamison N. Peschel

	
 
	
 
	
 

	
 
	
Its:
	
Authorized Signatory

	
 
	
 
	
 

	
 
	
Date:
	
7-07-16

 

	
 
	
“TENANT”

	
 
	
 

	
 
	
NOVAN, INC.,

	
 
	
a Delaware corporation

	
 
	
 
	
 

	
 
	
By:
	
/s/ Jeff N. Hunter

	
 
	
 
	
 

	
 
	
Its:
	
Jeff N. Hunter/Corporate Secretary

	
 
	
 
	
 

	
 
	
Date:
	
7-5-16novn-ex106_449.htm

 

Exhibit 10.6

FOURTH AMENDMENT TO LEASE AGREEMENT

THIS FOURTH AMENDMENT TO LEASE AGREEMENT (this “Agreement”) is made and entered into as of the 28th day of September, 2016, by and between DURHAM ROYAL CENTER, LLC, a Delaware limited liability company (“Landlord”) and NOVAN, INC., a Delaware corporation (“Tenant”).

STATEMENT OF PURPOSE

WHEREAS, Landlord’s predecessor in title and Tenant entered into a Lease Agreement dated as of December 21, 2010 as amended by that First Amendment to Lease Agreement dated August 27, 2013, as amended by that Second Amendment to Lease Agreement (the “Second Amendment”) dated August 27, 2015, and as amended by that Third Amendment to Lease Agreement (the “Third Amendment”) dated July 5, 2016 (collectively, the “Lease”) for certain premises containing approximately nineteen thousand three hundred sixty-seven (19,367) rentable square feet of space located at Suite 470 in the building known as Royal Center I and Suite 200 in the building known as Royal Center II both of which are located at 4222 Emperor Boulevard, Durham, North Carolina, as more particularly described in the Lease (the “Premises”). The Premises consists of Suite 470 of containing 12,147 rentable square feet (“Suite 470”) and Suite 200 containing 7,220 rentable square feet (“Suite 200”).

WHEREAS, Landlord and Tenant previously entered into the Second Amendment and later Third Amendment to terminate the term of lease for both Suite 470 and Suite 200 earlier than as stated in the Lease.

WHEREAS, Landlord and Tenant now desire to revise the termination date for Suite 470 only as stated herein and to otherwise amend the Lease as hereinafter provided.

NOW, THEREFORE, in consideration of the statement of purpose, the mutual covenants contained herein and other valuable consideration, the receipt of which is hereby acknowledged, the parties hereto agree as follows:

1. Termination of Lease. Notwithstanding anything contained in the Third Amendment or elsewhere in the Lease, Landlord and Tenant hereby agree that Tenant’s lease of Suite 470 shall continue until February 28, 2017 (the “Suite 470 Termination Date”). On the Suite 470 Termination Date, Tenant shall surrender Suite 470 to Landlord in the condition described in Section 1 of the Second Amendment. Tenant shall pay Minimum Rent for Suite 470 in accordance with Section 2 below.

2. Minimum Rent. Tenant shall continue to pay Minimum Rent for Suite 200 as stated in the Third Amendment until the Suite 200 Termination Date. Tenant shall pay Minimum Rent for Suite 470 according to the following schedule and otherwise in the manner provided for in the Lease:

Suite 470 Minimum Rent

	
 
	
Minimum Rental per
	
Monthly

	
Period
	
rentable square foot (yearly)
	
Minimum Rental

	
09/01/2016 – 02/28/2017
	
$17.06
	
$17,268.99

3. Tenant’s Share of Expenses. Tenant shall continue to pay Tenant’s Proportionate Share  of the Operating Expenses for the Premises in accordance with the Lease including any reconciliation after the applicable termination date for each suite.

300135510 v1

 

4. Representations and Warranties of Tenant. Tenant owns the entire leasehold interest granted by the Lease and has not assigned its leasehold interest, subleased the Premises nor granted a security interest in its leasehold interest that is the subject of the Lease and Tenant certifies that there are no tenants or other persons or entities having a right to possession of the Premises or any portion thereof after Tenant vacates the Premises. On or before the Termination Date, if applicable, Tenant shall satisfy, or obtain releases of, all outstanding liens or financing statements encumbering Tenant’s leasehold interest in the Premises.

5. Broker. Notwithstanding anything contained herein to the contrary, in no event shall any broker receive any compensation or commission relative to this Agreement.

6. Expenses. In the event that Tenant defaults under any of its obligations set forth above, Landlord shall be entitled to employ all rights and remedies available to it for enforcement of such obligations, and Tenant shall be responsible for paying any and all costs and expenses of the Landlord, including reasonable attorneys’ fees in enforcing the obligations of Tenant hereunder.

7. Benefits and Binding Effect. This Agreement shall be binding upon and shall inure to the benefit of the parties hereto and their respective successors and assigns.

8. Counterparts. This Agreement may be executed in one or more counterparts, each of which shall be deemed an original hereof, and all of which shall be considered one and the same instrument.

 

 

 

 

IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be duly executed pursuant to authority duly given as of the day and year first above written.

 

	
“LANDLORD”

	
 

	
DURHAM ROYAL CENTER, LLC,

	
a Delaware limited liability company

 

	
By:
	
 
	
/s/ Jamison N. Peschel

	
 
	
 
	
 

	
Its:
	
 
	
Jamison N. Peschel

	
 
	
 
	
Authorized Signatory

	
 
	
 
	
 

	
Date:
	
 
	
10/7/16

 

	
“TENANT”

	
 

	
NOVAN, INC.,

	
a Delaware corporation

 

	
By:
	
 
	
/s/ Richard Peterson

	
 
	
 
	
 

	
Its:
	
 
	
Richard Peterson/CFO

	
 
	
 
	
 

	
Date:
	
 
	
9/28/16

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