Document:

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                         CALYPTE BIOMEDICAL CORPORATION

                           2000 EQUITY INCENTIVE PLAN

                            As Adopted June 13, 2000

     1.   PURPOSE. The purpose of this Plan is to provide incentives to
attract, retain and motivate eligible persons whose present and potential
contributions are important to the success of the Company, its Parent and
Subsidiaries, if any, by offering them an opportunity to participate in the
Company's future performance through awards of Options, Restricted Stock and
Stock Bonuses. Capitalized terms not defined in the text are defined in
Section 23.

     2.   SHARES SUBJECT TO THE PLAN.

          2.1. NUMBER OF SHARES AVAILABLE. Subject to Sections 2.2 and 18,
the total number of Shares reserved and available for grant and issuance
pursuant to this Plan will be 4,000,000 Shares. Shares that: (a) are subject
to issuance upon exercise of an Option but cease to be subject to such Option
for any reason other than exercise of such Option; or (b) are subject to an
Award that otherwise terminates without Shares being issued, will again be
available for grant and issuance in connection with future Awards under this
Plan. Any authorized shares not issued or subject to outstanding grants under
the Prior Plan on the Effective Date and any shares that: (a) are issuable
upon exercise of options granted pursuant to the Prior Plan that expire or
become unexercisable for any reason without having been exercised in full;
(b) are subject to an award granted pursuant to the Prior Plan but such Award
has been exchanged by the holder thereof for awards granted under this Plan;
or (c) are subject to an award granted pursuant to the Prior Plan that
otherwise terminates without shares being issued, will no longer be available
for grant and issuance under the Prior Plan, but will be available for grant
and issuance under this Plan. At all times the Company shall reserve and keep
available a sufficient number of Shares as shall be required to satisfy the
requirements of all outstanding Options granted under this Plan and all other
outstanding but unvested Awards granted under this Plan.

          2.2. ADJUSTMENT OF SHARES. In the event that the number of outstanding
Shares is changed by a stock dividend, recapitalization, stock split, reverse
stock split, subdivision, combination, reclassification or similar change in the
capital structure of the Company without consideration, then (a) the number of
Shares reserved for issuance under this Plan, (b) the Exercise Prices of and
number of Shares subject to outstanding Options, and (c) the number of Shares
subject to other outstanding Awards will be proportionately adjusted, subject to
any required action by the Board or the stockholders of the Company and
compliance with applicable securities laws; provided, however, that fractions of
a Share will not be issued but will either be replaced by a cash payment equal
to the Fair Market Value of such fraction of a Share or will be rounded up to
the nearest whole Share, as determined by the Committee.

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     3.   ELIGIBILITY. ISOs may be granted only to employees (including
officers and directors who are also employees) of the Company or of a Parent
or Subsidiary. All other Awards may be granted to employees, officers,
directors, consultants, independent contractors and advisors of the Company
or any Parent or Subsidiary; provided such consultants, contractors and
advisors render bona fide services. No person will be eligible to receive
more than 900,000 Shares in any calendar year under this Plan pursuant to the
grant of Awards hereunder.

     4.   ADMINISTRATION.

               4.1. COMMITTEE AUTHORITY. This Plan will be administered by the
Committee or by the Board acting as the Committee. Subject to the general
purposes, terms and conditions of this Plan, and to the direction of the Board,
the Committee will have full power to implement and carry out this Plan. Without
limitation, the Committee will have the authority to:

                    (a)  construe and interpret this Plan, any Award Agreement
                         and any other agreement or document executed pursuant
                         to this Plan;

                    (b)  prescribe, amend and rescind rules and regulations
                         relating to this Plan;

                    (c)  select persons to receive Awards;

                    (d)  determine the form and terms of Awards;

                    (e)  determine the number of Shares or other consideration
                         subject to Awards;

                    (f)  determine whether Awards will be granted singly, in
                         combination with, in tandem with, in replacement of, or
                         as alternatives to, other Awards under this Plan or any
                         other incentive or compensation plan of the Company or
                         any Parent or Subsidiary;

                    (g)  grant waivers of Plan or Award conditions;

                    (h)  determine the vesting, exercisability and payment of
                         Awards;

                    (i)  correct any defect, supply any omission or reconcile
                         any inconsistency in this Plan, any Award or any Award
                         Agreement;

                    (j)  determine whether an Award has been earned; and

                    (k)  make all other determinations necessary or advisable
                         for the administration of this Plan.

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          4.2. COMMITTEE DISCRETION. Any determination made by the Committee
with respect to any Award will be made in its sole discretion at the time of
grant of the Award or, unless in contravention of any express term of this Plan
or Award, at any later time, and such determination will be final and binding on
the Company and on all persons having an interest in any Award under this Plan.
The Committee may delegate to one or more officers of the Company the authority
to grant an Award under this Plan to Participants who are not Insiders of the
Company.

          4.3. EXCHANGE ACT REQUIREMENTS. If two or more members of the Board
are Outside Directors, the Committee will be comprised of at least two (2)
members of the Board, all of whom are Outside Directors.

     5.   OPTIONS. The Committee may grant Options to eligible persons and will
determine whether such Options will be ISOs or NQSOs, the number of Shares
subject to the Option, the Exercise Price of the Option, the period during which
the Option may be exercised, and all other terms and conditions of the Option,
subject to the following:

          5.1. FORM OF OPTION GRANT. Each Option granted under this Plan will be
evidenced by an Award Agreement which will expressly identify the Option as an
ISO or an NQSO and will be in such form and contain such provisions (which need
not be the same for each Participant) as the Committee may from time to time
approve, and which will comply with and be subject to the terms and conditions
of this Plan.

          5.2. DATE OF GRANT. The date of grant of an Option will be the date on
which the Committee makes the determination to grant such Option, unless
otherwise specified by the Committee. The Stock Option Agreement and a copy of
this Plan will be delivered to the Participant within a reasonable time after
the granting of the Option.

          5.3. EXERCISE PERIOD. Options may be exercisable immediately (subject
to repurchase pursuant to Section 12 of this Plan) or may be exercisable within
the times or upon the events determined by the Committee as set forth in the
Stock Option Agreement governing such Option; provided, however, that no Option
will be exercisable after the expiration of ten (10) years from the date the
Option is granted; and provided further that no ISO granted to a Ten Percent
Stockholder will be exercisable after the expiration of five (5) years from the
date the ISO is granted. The Committee also may provide for the exercise of
Options to become exercisable at one time or from time to time, periodically or
otherwise, in such number of Shares or percentage of Shares as the Committee
determines.

          5.4. EXERCISE PRICE. The Exercise Price of an Option will be
determined by the Committee when the Option is granted and shall not be less
than 85% of the Fair Market Value of the Shares on the date of grant;
provided that: (i) the Exercise Price of an ISO will be not less than 100% of
the Fair Market Value of the Shares on the date of grant; and (ii) the
Exercise Price of any ISO granted to a Ten Percent Stockholder will not be
less than 110% of the Fair Market

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Value of the Shares on the date of grant. Payment for the Shares purchased may
be made in accordance with Section 8 of this Plan.

          5.5. METHOD OF EXERCISE. Options may be exercised only by delivery to
the Company of a written stock option exercise agreement (the "EXERCISE
AGREEMENT") in a form approved by the Committee (which need not be the same for
each Participant), stating the number of Shares being purchased, the
restrictions imposed on the Shares purchased under such Exercise Agreement, if
any, and such representations and agreements regarding Participant's investment
intent and access to information and other matters, if any, as may be required
or desirable by the Company to comply with applicable securities laws, together
with payment in full of the Exercise Price for the number of Shares being
purchased.

          5.6. TERMINATION. Notwithstanding the exercise periods set forth in an
Award Agreement, exercise of an Option will always be subject to the following:

               (a)  If the Participant is Terminated for any reason except
                    death or Disability, then the Participant may exercise
                    such Participant's Options to the extent such
                    Participant's Option would have been exercisable upon
                    the Termination Date, or to such greater extent as
                    otherwise determined by the Committee, no later than
                    three (3) months after the Termination Date (or such
                    shorter or longer time period not exceeding five (5)
                    years as may be determined by the Committee, with any
                    exercise beyond three (3) months after the Termination
                    Date deemed to be an NQSO), but in any event, no later
                    than the expiration date of the Options.

               (b)  If the Participant is Terminated because of Participant's
                    death or Disability (or the Participant dies within three
                    (3) months after a Termination other than because of
                    Participant's death or disability), then Participant's
                    Options may be exercised and must be exercised by
                    Participant (or Participant's legal representative or
                    authorized assignee) to the extent such Participant's
                    Option would have been exercisable on the Termination
                    Date, or to such greater extent as otherwise determined
                    by the Committee, no later than twelve (12) months after
                    the Termination Date (or such shorter or longer time
                    period not exceeding five (5) years as may be determined
                    by the Committee, with any such exercise beyond (a) three
                    (3) months after the Termination Date when the
                    Termination is for any reason other than the
                    Participant's death or Disability, or (b) twelve (12)
                    months after the Termination Date when the Termination is
                    for Participant's death or Disability, deemed to be an
                    NQSO), but in any event no later than the expiration date
                    of the Options.

               (c)  If a Participant is determined by the Board to have
                    committed on act of theft, embezzlement, fraud, dishonesty,
                    a breach of fiduciary duty to the Company or Subsidiary, or
                    deliberate disregard of the rules of the Company or
                    Subsidiary, or if a Participant makes any unauthorized
                    disclosure of any of the trade secrets or confidential

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                    information of the Company or Subsidiary, engages in any
                    conduct which constitutes unfair competition with the
                    Company or Subsidiary, induces any customer of the Company
                    or Subsidiary to break any contract with the Company or
                    Subsidiary, or induces any principal for whom the Company or
                    Subsidiary acts as agent to terminate such agency
                    relationship, (each of which acts by the Participant shall
                    constitute "Misconduct" for purposes of this Plan) neither
                    the Participant, the Participant's estate nor such other
                    person who may then hold the Option shall be entitled to
                    exercise any Option with respect to any Shares whatsoever,
                    after termination of service, whether or not after
                    termination of service the Participant may receive payment
                    from the Company or Subsidiary for vacation pay, for
                    services rendered prior to termination, for services
                    rendered for the day on which termination occurs, for salary
                    in lieu of notice, or for any other benefits. In making such
                    determination, the Board shall give the Participant an
                    opportunity to present to the Board evidence on his behalf.
                    For the purpose of this paragraph, termination of service
                    shall be deemed to occur on the date when the Company
                    dispatches notice or advice to the Participant that his
                    service is terminated.

               (d)  If any Participant's employment is terminated by the Company
                    for any reason other than for Misconduct or, if applicable,
                    by Constructive Termination, within one year after a Change
                    of Control has occurred, then all Options held by such
                    Participant shall become fully vested for exercise upon the
                    date of termination, irrespective of the vesting provisions
                    of the Participant's Option agreement. For purposes of this
                    subsection (d), the term "Change of Control" shall have the
                    meaning assigned by this Plan, unless a different meaning is
                    defined in an individual Participant's Option.

          5.7. LIMITATIONS ON EXERCISE. The Committee may specify a reasonable
minimum number of Shares that may be purchased on any exercise of an Option,
provided that such minimum number will not prevent Participant from exercising
the Option for the full number of Shares for which it is then exercisable.

          5.8. LIMITATIONS ON ISOS. If the Fair Market Value of Shares on the
date of grant with respect to which ISOs are exercisable for the first time
by a Participant during any calendar year exceeds $100,000, then the Options
for the first $100,000 worth of Shares to become exercisable in such calendar
year (under this Plan or under any other incentive stock option plan of the
Company or any Parent or Subsidiary) will be ISOs and the Options for the
amount in excess of $100,000 that become exercisable in that calendar year
will be NQSOs. In the event that the Code or the regulations promulgated
thereunder are amended after the Effective Date of this Plan to provide for a
different limit on the Fair Market Value of

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Shares permitted to be subject to ISOs, such different limit will be
automatically incorporated herein and will apply to any Options granted after
the effective date of such amendment.

          5.9. MODIFICATION, EXTENSION OR RENEWAL. The Committee may modify,
extend or renew outstanding Options and authorize the grant of new Options in
substitution therefor, provided that any such action may not, without the
written consent of a Participant, impair any of such Participant's rights under
any Option previously granted. Any outstanding ISO that is modified, extended,
renewed or otherwise altered will be treated in accordance with Section 424(h)
of the Code.

          5.10. NO DISQUALIFICATION. Notwithstanding any other provision in this
Plan, no term of this Plan relating to ISOs will be interpreted, amended or
altered, nor will any discretion or authority granted under this Plan be
exercised, so as to disqualify this Plan under Section 422 of the Code or,
without the consent of the Participant affected, to disqualify any ISO under
Section 422 of the Code.

     6.   RESTRICTED STOCK. A Restricted Stock Award is an offer by the Company
to sell to an eligible person Shares that are subject to restrictions. The
Committee will determine to whom an offer will be made, the number of Shares the
person may purchase, the price to be paid (the "PURCHASE PRICE"), the
restrictions to which the Shares will be subject, and all other terms and
conditions of the Restricted Stock Award, subject to the following:

          6.1. FORM OF RESTRICTED STOCK AWARD. All purchases under a Restricted
Stock Award made pursuant to this Plan will be evidenced by an Award Agreement
("RESTRICTED STOCK PURCHASE AGREEMENT") that will be in such form (which need
not be the same for each Participant) as the Committee will from time to time
approve, and will comply with and be subject to the terms and conditions of this
Plan. The offer of Restricted Stock will be accepted by the Participant's
execution and delivery of the Restricted Stock Purchase Agreement and full
payment for the Shares to the Company within thirty (30) days from the date the
Restricted Stock Purchase Agreement is delivered to the person. If such person
does not execute and deliver the Restricted Stock Purchase Agreement along with
full payment for the Shares to the Company within thirty (30) days, then the
offer will terminate, unless otherwise determined by the Committee.

          6.2. PURCHASE PRICE. The Purchase Price of Shares sold pursuant to a
Restricted Stock Award will be determined by the Committee and will be at least
85% of the Fair Market Value of the Shares on the date the Restricted Stock
Award is granted, except in the case of a sale to a Ten Percent Stockholder, in
which case the Purchase Price will be 100% of the Fair Market Value. Payment of
the Purchase Price may be made in accordance with Section 8 of this Plan.

          6.3. RESTRICTIONS. Restricted Stock Awards will be subject to such
restrictions (if any) as the Committee may impose. The Committee may provide for
the lapse of such

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restrictions in installments and may accelerate or waive such restrictions, in
whole or part, based on length of service, performance or such other factors or
criteria as the Committee may determine.

     7.   STOCK BONUSES.

          7.1. AWARDS OF STOCK BONUSES. A Stock Bonus is an award of Shares
(which may consist of Restricted Stock) for services rendered to the Company or
any Parent or Subsidiary. A Stock Bonus may be awarded for past services already
rendered to the Company, or any Parent or Subsidiary pursuant to an Award
Agreement (the "STOCK BONUS AGREEMENT") that will be in such form (which need
not be the same for each Participant) as the Committee will from time to time
approve, and will comply with and be subject to the terms and conditions of this
Plan. A Stock Bonus may be awarded upon satisfaction of such performance goals
as are set out in advance in the Participant's individual Award Agreement (the
"PERFORMANCE STOCK BONUS AGREEMENT") that will be in such form (which need not
be the same for each Participant) as the Committee will from time to time
approve, and will comply with and be subject to the terms and conditions of this
Plan. Stock Bonuses may vary from Participant to Participant and between groups
of Participants, and may be based upon the achievement of the Company, Parent
and/or Subsidiary individual performance factors or upon such other criteria as
the Committee may determine.

          7.2. TERMS OF STOCK BONUSES. The Committee will determine the number
of Shares to be awarded to the Participant and whether such Shares will be
Restricted Stock. If the Stock Bonus is being earned upon the satisfaction of
performance goals pursuant to a Performance Stock Bonus Agreement, then the
Committee will determine: (a) the nature, length and starting date of any period
during which performance is to be measured (the "PERFORMANCE PERIOD") for each
Stock Bonus; (b) the performance goals and criteria to be used to measure the
performance, if any; (c) the number of Shares that may be awarded to the
Participant; and (d) the extent to which such Stock Bonuses have been earned.
Performance Periods may overlap and Participants may participate simultaneously
with respect to Stock Bonuses that are subject to different Performance Periods
and different performance goals and other criteria. The number of Shares may be
fixed or may vary in accordance with such performance goals and criteria as may
be determined by the Committee. The Committee may adjust the performance goals
applicable to the Stock Bonuses to take into account changes in law and
accounting or tax rules and to make such adjustments as the Committee deems
necessary or appropriate to reflect the impact of extraordinary or unusual
items, events or circumstances to avoid windfalls or hardships.

          7.3. FORM OF PAYMENT. The earned portion of a Stock Bonus may be paid
currently or on a deferred basis with such interest or dividend equivalent, if
any, as the Committee may determine. Payment may be made in the form of cash,
whole Shares, including Restricted Stock, or a combination thereof, either in a
lump sum payment or in installments, all as the Committee will determine.

          7.4. TERMINATION DURING PERFORMANCE PERIOD. If a Participant is
Terminated during a Performance Period for any reason, then such Participant
will be entitled to payment (whether in Shares, cash or otherwise) with respect
to the Stock Bonus only to the extent earned

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as of the date of Termination in accordance with the Performance Stock Bonus
Agreement, unless the Committee will determine otherwise.

     8.   PAYMENT FOR SHARE PURCHASES.

          8.1. PAYMENT. Payment for Shares purchased pursuant to this Plan
may be made by a form of lawful consideration approved by the Committee
including, without limitation, the following:

               (a)  by cancellation of indebtedness of the Company to the
                    Participant;

               (b)  by surrender of shares that either: (1) have been owned by
                    Participant for more than six (6) months and have been paid
                    for within the meaning of SEC Rule 144 (and, if such shares
                    were purchased from the Company by use of a promissory note,
                    such note has been fully paid with respect to such shares);
                    or (2) were obtained by Participant in the public market;

               (c)  by tender of a full recourse promissory note having such
                    terms as may be approved by the Committee and bearing
                    interest at a rate sufficient to avoid imputation of income
                    under Sections 483 and 1274 of the Code; provided, however,
                    that Participants who are not employees or directors of the
                    Company will not be entitled to purchase Shares with a
                    promissory note unless the note is adequately secured by
                    collateral other than the Shares;

               (d)  by waiver of compensation due or accrued to the Participant
                    for services rendered;

               (e)  with respect only to purchases upon exercise of an Option,
                    and provided that a public market for the Company's stock
                    exists:

                    (1)  through a "same day sale" commitment from the
                         Participant and a broker-dealer that is a member of the
                         National Association of Securities Dealers (an "NASD
                         DEALER") whereby the Participant irrevocably elects to
                         exercise the Option and to sell a portion of the Shares
                         so purchased to pay for the Exercise Price, and whereby
                         the NASD Dealer irrevocably commits upon receipt of
                         such Shares to forward the Exercise Price directly to
                         the Company; or

                    (2)  through a "margin" commitment from the Participant and
                         a NASD Dealer whereby the Participant irrevocably
                         elects to exercise the Option and to pledge the Shares
                         so purchased to the NASD Dealer in a margin account as
                         security for a loan from the NASD Dealer in the amount
                         of the Exercise

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                         Price, and whereby the NASD Dealer irrevocably commits
                         upon receipt of such Shares to forward the Exercise
                         Price directly to the Company

               (f)  by any combination of the foregoing; or

               (g)  the exchange of any other form of consideration from the
                    Participant to the Company that is lawful consideration
                    for the issuance of securities sufficient for such
                    securities to be deemed fully paid and nonassessable
                    under the Delaware General Corporation Law.

          8.2. LOAN GUARANTEES. The Committee may help the Participant pay for
Shares purchased under this Plan by authorizing a guarantee by the Company of a
third-party loan to the Participant.

          8.3. Notwithstanding Sections 8.1(c) and 8.2, any Participant
executing rights and obtaining Shares pursuant to awards granted under this Plan
must pay cash or other valid consideration equal to aggregate par value of such
Shares to the extent required by the Delaware General Corporation Law.

     9.   WITHHOLDING TAXES.

          9.1. WITHHOLDING GENERALLY. Whenever Shares are to be issued in
satisfaction of Awards granted under this Plan, the Company may require the
Participant to remit to the Company an amount sufficient to satisfy federal,
state and local withholding tax requirements prior to the delivery of any
certificate or certificates for such Shares. Whenever, under this Plan, payments
in satisfaction of Awards are to be made in cash, such payment will be net of an
amount sufficient to satisfy federal, state, and local withholding tax
requirements.

          9.2. STOCK WITHHOLDING. When, under applicable tax laws, a Participant
incurs tax liability in connection with the exercise or vesting of any Award
that is subject to tax withholding and the Participant is obligated to pay the
Company the amount required to be withheld, the Committee may in its sole
discretion allow the Participant to satisfy the minimum withholding tax
obligation by electing to have the Company withhold from the Shares to be issued
that number of Shares having a Fair Market Value equal to the minimum amount
required to be withheld, determined on the date that the amount of tax to be
withheld is to be determined (the "TAX DATE"). All elections by a Participant to
have Shares withheld for this purpose will be made in writing in a form
acceptable to the Committee and will be subject to the following restrictions:

               (a)  the election must be made on or prior to the applicable Tax
                    Date;

               (b)  once made, then except as provided below, the election will
                    be irrevocable as to the particular Shares as to which the
                    election is made;

               (c)  all elections will be subject to the consent or disapproval
                    of the Committee;

               (d)  if the Participant is an Insider and if the Company is
                    subject to Section 16(b) of the Exchange Act: (1) the
                    election may not be made within six (6) months of the date
                    of grant of the Award,

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                    except as otherwise permitted by SEC Rule 16b-3(e) under the
                    Exchange Act, and (2) either (A) the election to use stock
                    withholding must be irrevocably made at least six (6) months
                    prior to the Tax Date (although such election may be revoked
                    at any time at least six (6) months prior to the Tax Date)
                    or (B) the exercise of the Option or election to use stock
                    withholding must be made in the ten (10) day period
                    beginning on the third day following the release of the
                    Company's quarterly or annual summary statement of sales or
                    earnings; and

               (e)  in the event that the Tax Date is deferred until six (6)
                    months after the delivery of Shares under Section 83(b) of
                    the Code, the Participant will receive the full number of
                    Shares with respect to which the exercise occurs, but such
                    Participant will be unconditionally obligated to tender back
                    to the Company the proper number of Shares on the Tax Date.

     10.  PRIVILEGES OF STOCK OWNERSHIP.

          10.1. VOTING AND DIVIDENDS. No Participant will have any of the rights
of a stockholder with respect to any Shares until the Shares are issued to the
Participant. After Shares are issued to the Participant, the Participant will be
a stockholder and have all the rights of a stockholder with respect to such
Shares, including the right to vote and receive all dividends or other
distributions made or paid with respect to such Shares; provided, that if such
Shares are Restricted Stock, then any new, additional or different securities
the Participant may become entitled to receive with respect to such Shares by
virtue of a stock dividend, stock split or any other change in the corporate or
capital structure of the Company will be subject to the same restrictions as the
Restricted Stock; provided, further, that the Participant will have no right to
retain such stock dividends or stock distributions with respect to Shares that
are repurchased at the Participant's original Purchase Price pursuant to Section
12.

          10.2. FINANCIAL STATEMENTS. The Company will make available
financial statements to each Participant prior to such Participant's purchase
of Shares under this Plan, and to each Participant annually during the period
such Participant has Awards outstanding; provided, however, the Company will
not be required to provide such financial statements to Participants whose
services in connection with the Company assure them access to equivalent
information. This obligation is deemed to be satisfied for so long as the
Company is a reporting company subject to Section 13 or 15(d) of the Exchange
Act.

     11.  TRANSFERABILITY. Awards granted under this Plan, and any interest
therein, will not be transferable or assignable by Participant, and may not be
made subject to execution, attachment or similar process, otherwise than by will
or by the laws of descent and distribution or as consistent with the specific
Plan and Award Agreement provisions relating thereto. During the lifetime of the
Participant an Award will be exercisable only by the Participant, and any
elections with respect to an Award, may be made only by the Participant.

     12.  RESTRICTIONS ON SHARES. At the discretion of the Committee, the
Company may reserve to itself and/or its assignee(s) in the Award Agreement a
right to repurchase a portion of or all Shares held by a Participant following
such Participant's

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Termination at any time within ninety (90) days after the later of Participant's
Termination Date and the date Participant purchases Shares under this Plan, for
cash and/or cancellation of purchase money indebtedness, at: (A) with respect to
Shares that are "Vested" (as defined in the Award Agreement), the higher of: (l)
Participant's original Purchase Price, or (2) the Fair Market Value of such
Shares on Participant's Termination Date, provided, that such right of
repurchase (i) must be exercised as to all such "Vested" Shares unless a
Participant consents to the Company's repurchase of only a portion of such
"Vested" Shares and (ii) terminates when the Company's securities become
publicly traded; or (B) with respect to Shares that are not "Vested" (as defined
in the Award Agreement), at the Participant's original Purchase Price, provided,
that the right to repurchase at the original Purchase Price lapses at the rate
of at least 20% per year over five (5) years from the date the Shares were
purchased (or from the date of grant of options in the case of Shares obtained
pursuant to an Award Agreement and Stock Option Exercise Agreement), and if the
right to repurchase is assignable, the assignee must pay the Company, upon
assignment of the right to repurchase, cash equal to the excess of the Fair
Market Value of the Shares over the original Purchase Price.

     13.  CERTIFICATES. All certificates for Shares or other securities
delivered under this Plan will be subject to such stock transfer orders, legends
and other restrictions as the Committee may deem necessary or advisable,
including restrictions under any applicable federal, state or foreign securities
law, or any rules, regulations and other requirements of the SEC or any stock
exchange or automated quotation system upon which the Shares may be listed or
quoted.

     14.  ESCROW; PLEDGE OF SHARES. To enforce any restrictions on a
Participant's Shares, the Committee may require the Participant to deposit all
certificates representing Shares, together with stock powers or other
instruments of transfer approved by the Committee, appropriately endorsed in
blank, with the Company or an agent designated by the Company to hold in escrow
until such restrictions have lapsed or terminated, and the Committee may cause a
legend or legends referencing such restrictions to be placed on the
certificates. Any Participant who is permitted to execute a promissory note as
partial or full consideration for the purchase of Shares under this Plan will be
required to pledge and deposit with the Company all or part of the Shares so
purchased as collateral to secure the payment of Participant's obligation to the
Company under the promissory note; provided, however, that the Committee may
require or accept other or additional forms of collateral to secure the payment
of such obligation and, in any event, the Company will have full recourse
against the Participant under the promissory note notwithstanding any pledge of
the Participant's Shares or other collateral. In connection with any pledge of
the Shares, Participant will be required to execute and deliver a written pledge
agreement in such form as the Committee will from time to time approve. The
Shares purchased with the promissory note may be released from the pledge on a
pro rata basis as the promissory note is paid.

     15.  EXCHANGE AND BUYOUT OF AWARDS. The Committee may, at any time or from
time to time, authorize the Company, with the consent of the respective
Participants, to issue new Awards in exchange for the surrender and cancellation
of any or all outstanding Awards. The Committee may at any time buy from a
Participant an Award previously granted with payment in cash, Shares (including
Restricted Stock) or other consideration, based on such terms and conditions as
the Committee and the Participant may agree.

                                      -11-
<PAGE>

     16.  SECURITIES LAW AND OTHER REGULATORY COMPLIANCE. An Award will not be
effective unless such Award is in compliance with all applicable federal and
state securities laws, rules and regulations of any governmental body, and the
requirements of any stock exchange or automated quotation system upon which the
Shares may then be listed or quoted, as they are in effect on the date of grant
of the Award and also on the date of exercise or other issuance. Notwithstanding
any other provision in this Plan, the Company will have no obligation to issue
or deliver certificates for Shares under this Plan prior to: (a) obtaining any
approvals from governmental agencies that the Company determines are necessary
or advisable; and/or (b) completion of any registration or other qualification
of such Shares under any state or federal law or ruling of any governmental body
that the Company determines to be necessary or advisable. The Company will be
under no obligation to register the Shares with the SEC or to effect compliance
with the registration, qualification or listing requirements of any state
securities laws, stock exchange or automated quotation system, and the Company
will have no liability for any inability or failure to do so.

     17.  NO OBLIGATION TO EMPLOY. Nothing in this Plan or any Award granted
under this Plan will confer or be deemed to confer on any Participant any right
to continue in the employ of, or to continue any other relationship with, the
Company or any Parent or Subsidiary or limit in any way the right of the Company
or any Parent or Subsidiary to terminate Participant's employment or other
relationship at any time, with or without cause.

     18.  CORPORATE TRANSACTIONS.

          18.1. ASSUMPTION OR REPLACEMENT OF AWARDS BY SUCCESSOR. In the event
of (a) a dissolution or liquidation of the Company, (b) a merger or
consolidation in which the Company is not the surviving corporation (other than
a merger or consolidation with a wholly-owned subsidiary, a reincorporation of
the Company in a different jurisdiction, or other transaction in which there is
no substantial change in the stockholders of the Company or their relative stock
holdings and the Awards granted under this Plan are assumed, converted or
replaced by the successor corporation, which assumption will be binding on all
Participants), (c) a merger in which the Company is the surviving corporation
but after which stockholders owning more than 50% of the voting stock of the
Company (other than any stockholder which merges, or which owns or controls
another corporation which merges, with the Company in such merger) cease to own
their shares or other equity interests in the Company, or (d) the sale of all or
substantially all of the assets of the Company, any or all outstanding Awards
may be assumed, converted or replaced by the successor corporation (if any),
which assumption, conversion or replacement will be binding on all Participants.
In the alternative, the successor corporation may substitute equivalent Awards
or provide substantially similar consideration to Participants as was provided
to stockholders (after taking into account the existing provisions of the
Awards). The successor corporation may also issue, in place of outstanding
Shares of the Company held by the Participant, substantially similar shares or
other property subject to repurchase restrictions no less favorable to the
Participant. Notwithstanding the foregoing, if (a) any Participant whose options
are (i) assumed, converted or replaced by the successor corporation (if any), or
(ii) substituted by the successor corporation with equivalent Awards or
substantially similar consideration; and (b) such Participant is terminated
without cause within six months of the consummation of a transaction of the type
described above by the Company or a successor corporation (if any); then (c) any
Options held by the Participant will immediately accelerate

                                      -12-
<PAGE>

and become fully vested and exercisable by the Participant. In the event such
successor corporation (if any) refuses to assume or substitute Options, as
provided above, pursuant to a transaction described in this Subsection 18.1,
then notwithstanding any other provision in this Plan to the contrary, such
Options will accelerate at such time and on such conditions as the Board
determines.

          18.2. OTHER TREATMENT OF AWARDS. Subject to any greater rights granted
to Participants under the foregoing provisions of this Section 18, in the event
of the occurrence of any transaction described in Section 18.1, any outstanding
Awards will be treated as provided in the applicable agreement or plan of
merger, consolidation, dissolution, liquidation, sale of assets or other
"corporate transaction."

          18.3. ASSUMPTION OF AWARDS BY THE COMPANY. The Company, from time to
time, also may substitute or assume outstanding awards granted by another
company, whether in connection with an acquisition of such other company or
otherwise, by either; (a) granting an Award under this Plan in substitution of
such other company's award; or (b) assuming such award as if it had been granted
under this Plan if the terms of such assumed award could be applied to an Award
granted under this Plan. Such substitution or assumption will be permissible if
the holder of the substituted or assumed award would have been eligible to be
granted an Award under this Plan if the other company had applied the rules of
this Plan to such grant. In the event the Company assumes an award granted by
another company, the terms and conditions of such award will remain unchanged
(except that the exercise price and the number and nature of Shares issuable
upon exercise of any such option will be adjusted appropriately pursuant to
Section 424(a) of the Code). In the event the Company elects to grant a new
Option rather than assuming an existing option, such new Option may be granted
with a similarly adjusted Exercise Price.

     19.  EFFECTIVE DATE. This Plan will become effective on the date it is
approved by the stockholders of the Company (the "Effective Date").

     20.  TERM OF PLAN/GOVERNING LAW. This Plan will terminate ten (10) years
from the date it is approved by the stockholders. This Plan and all
agreements thereunder shall be governed by and construed in accordance with
the laws of the State of Delaware.

     21.  AMENDMENT OR TERMINATION OF PLAN. The Board may at any time terminate
or amend this Plan in any respect, including without limitation amendment of any
form of Award Agreement or instrument to be executed pursuant to this Plan;
provided, however, that the Board will not, without the approval of the
stockholders of the Company, amend this Plan in any manner that requires such
stockholder approval pursuant to the Code or the regulations promulgated
thereunder as such provisions apply to ISO plans or (if the Company is subject
to the Exchange Act or Section 16(b) of the Exchange Act) pursuant to the
Exchange Act or Rule 16b-3 (or its successor), as amended, thereunder,
respectively.

     22.  NONEXCLUSIVITY OF THE PLAN. Neither the adoption of this Plan by the
Board, the submission of this Plan to the stockholders of the Company for
approval, nor any provision of this Plan will be construed as creating any
limitations on the power of the Board to

                                      -13-
<PAGE>

adopt such additional compensation arrangements as it may deem desirable,
including, without limitation, the granting of stock options and bonuses
otherwise than under this Plan, and such arrangements may be either generally
applicable or applicable only in specific cases.

     23.  DEFINITIONS. As used in this Plan, the following terms will have the
following meanings:

          "AWARD" means any award under this Plan, including any Option,
Restricted Stock or Stock Bonus.

          "AWARD AGREEMENT" means, with respect to each Award, the signed
written agreement between the Company and the Participant setting forth the
terms and conditions of the Award.

          "BOARD" means the Board of Directors of the Company.

          "CHANGE OF CONTROL" means any of the following events:

(i) any "person" (as such term is used in Sections 13(d) and 14(d) of the
Exchange Act) who is or becomes the beneficial owner (as defined in Rule
13d-3 under the Exchange Act), directly or indirectly, of securities of the
Company (not including in the securities beneficially owned by such person
any securities acquired directly from the Company or any of its Affiliates)
representing more than 20% of either the then outstanding shares of the
Common Stock of the Company or the combined voting power of the Company's
then outstanding voting securities; (ii) during any period of two consecutive
years, individuals who at the beginning of such period constituted the Board
and any new director (other than a director designated by a person who has
entered into an agreement or arrangement with the Company to effect a
transaction described in clause (i) or (ii) of this sentence) whose
appointment, election, or nomination for election by the Company's
stockholders, was approved by a vote of at least two-thirds (2/3) of the
directors then still in office who either were directors at the beginning of
the period or whose appointment, election or nomination for election was
previously so approved, cease for any reason to constitute a majority of the
Board; or (iii) there is consummated a merger or consolidation of the Company
or subsidiary thereof with or into any other corporation, other than a merger
or consolidation which would result in the holders of the voting securities
of the Company outstanding immediately prior thereto holding securities which
represent immediately after such merger or consolidation more than 50% of the
combined voting power of the voting securities of either the Company or the
other entity which survives such merger or consolidation or the parent of the
entity which survives such merger or consolidation; or (iv) the stockholders
of the Company approve a plan of complete liquidation of the Company or there
is consummated the sale or disposition by the Company of all or substantially
all of the Company's assets, other than a sale or disposition by the Company
of all or substantially all of the Company's assets to an entity, more than
50% of the combined voting power of the voting securities of which are owned
by persons in substantially the same proportions as their ownership of the
Company immediately prior to such sale. Notwithstanding the foregoing (i) no
"Change of Control" shall be deemed to have occurred if there is consummated
any transaction or series of integrated transactions immediately following
which the record holders of the Common Stock of the Company immediately prior
to such transaction or series of transactions continue to have substantially
the

                                      -14-
<PAGE>

same proportionate ownership in an entity which owns all or substantially all
of the assets of the Company immediately prior to such transaction or series
of transactions and (ii) "Change of Control" shall exclude the acquisition of
securities representing more than 20% of either the then outstanding shares
of the Common Stock of the Company or the combined voting power of the
Company's then outstanding voting securities by the Company or any of its
wholly owned subsidiaries, or any trustee or other fiduciary holding
securities of the Company under an employee benefit plan now or hereafter
established by the Company.

          "CODE" means the Internal Revenue Code of 1986, as amended.

          "COMMITTEE" means the committee appointed by the Board to administer
this Plan, or if no such committee is appointed, the Board.

          "COMPANY" means Calypte Biomedical Corporation or any successor
corporation.

          "CONSTRUCTIVE TERMINATION" means a resignation by a Participant who
has been elected by the Board as a corporate officer of the Company due to
diminution or adverse change in the circumstances of such Participant's
employment with the Company, as determined in good faith by the Participant;
including, without limitation, reporting relationships, job description, duties,
responsibilities, compensation, perquisites, office or location of employment.
Constructive Termination shall be communicated by written notice to the Company,
and such termination shall be deemed to occur on the date such notice is
delivered to the Company.

          "DISABILITY" means a disability, whether temporary or permanent,
partial or total, within the meaning of Section 22(e)(3) of the Code, as
determined by the Committee.

          "EFFECTIVE DATE" shall have the meaning given to it in Section 19.

          "EXCHANGE ACT" means the Securities Exchange Act of 1934, as amended.

          "EXERCISE AGREEMENT" shall have the meaning given to it in Section
5.5.

          "EXERCISE PRICE" means the price at which a holder of an Option may
purchase the Shares issuable upon exercise of the Option.

          "FAIR MARKET VALUE" means, as of any date, the value of a share of the
Company's Common Stock determined as follows:

                                      -15-
<PAGE>

          (a)       if such Common Stock is then quoted on the Nasdaq
                    National or SmallCap Markets, its closing price on the
                    Nasdaq National Market on the last trading day prior to
                    the date of determination as reported in The Wall Street
                    Journal;

          (b)       if such Common Stock is publicly traded and is then listed
                    on a national securities exchange, its closing price on the
                    last trading day prior to the date of determination on the
                    principal national securities exchange on which the Common
                    Stock is listed or admitted to trading as reported in The
                    Wall Street Journal;

          (c)       if such Common Stock is publicly traded but is not quoted
                    on the Nasdaq National or SmallCap Markets nor listed or
                    admitted to trading on a national securities exchange,
                    the average of the closing bid and asked prices on the
                    last trading day prior to the date of determination as
                    reported in The Wall Street Journal; or

          (d)       if none of the foregoing is applicable, by the Committee in
                    good faith.

          "INSIDER" means an officer or director of the Company or any other
person whose transactions in the Company's Common Stock are subject to Section
16 of the Exchange Act.

          "ISO" means incentive stock option within the meaning of the Code.

          "NQSO" means non-qualified stock option.

          "OUTSIDE DIRECTOR" means any director who: (a) is not a current
officer or employee of the Company or any Parent or Subsidiary; (b) is not
currently receiving, and since the beginning of the Company's previous fiscal
year has not received, compensation in excess of $60,000 for personal
services in any capacity from the Company or any Parent or Subsidiary; (c)
does not possess, and since the beginning of the Company's previous fiscal
year has not possessed, an interest in any transaction or series of similar
transactions with the Company in which the amount involved exceeds $60,000;
or (d) is not engaged in a business relationship with the Company for which
disclosure would be required pursuant to Item 402(b) of Regulation S-K of
the Exchange Act; provided, however, that if at such time as the term
"Outside Director," as used in Section 162(m) of the Code is defined in
regulations promulgated under Section 162(m) of the Code, "Outside Director"
will have the meaning set forth in such regulations, as amended from time to
time and as interpreted by the Internal Revenue Service.

          "OPTION" means an award of an option to purchase Shares pursuant
to Section 5.

          "PARENT" means any corporation (other than the Company) in an unbroken
chain of corporations ending with the Company, if at the time of the granting of
an Award under this Plan, each of such corporations other than the Company owns
stock possessing 50% or more of the total combined voting power of all classes
of stock in one of the other corporations in such chain.

                                      -16-
<PAGE>

          "PARTICIPANT" means a person who receives an Award under this Plan.

          "PLAN" means this Calypte Biomedical Corporation 2000 Equity Incentive
Plan, as amended from time to time.

          "PRIOR PLAN" means the Calypte Biomedical Corporation 1991 Stock
Option Plan.

          "PURCHASE PRICE" shall have the meaning given to it in Section 6.1.

          "RESTRICTED STOCK AWARD" means an award of Shares pursuant to Section
6.

          "RESTRICTED STOCK PURCHASE AGREEMENT" shall have the meaning given to
it in Section 6.1.

          "SEC" means the Securities and Exchange Commission.

          "SECURITIES ACT" means the Securities Act of 1933, as amended.

          "SHARES" means shares of the Company's Common Stock reserved for
issuance under this Plan, as adjusted pursuant to Sections 2 and 18, and any
successor security.

          "STOCK BONUS" means an award of Shares, or cash in lieu of Shares,
pursuant to Section 7.

          "SUBSIDIARY" means any corporation (other than the Company) in an
unbroken chain of corporations beginning with the Company if each of the
corporations other than the last corporation in the unbroken chain owns stock
possessing 50% or more of the total combined voting power of all classes of
stock in one of the other corporations in such chain.

          "TEN PERCENT SHAREHOLDER" means any person who directly or by
attribution owns more than 10% of the total combined voting power of all classes
of stock of the Company or of any Parent or Subsidiary.

          "TERMINATION" or "TERMINATED" means, for purposes of this Plan with
respect to a Participant, that the Participant has for any reason ceased to
provide services as an employee, director, consultant or advisor to the Company
or a Parent or Subsidiary. An employee will not be deemed to have ceased to
provide services in the case of (i) sick leave, (ii) military leave, or (iii)
any other leave of absence approved by the Committee, provided, that such leave
is for a period of not more than 90 days, unless reemployment upon the
expiration of such leave is guaranteed by contract or statute or unless provided
otherwise pursuant to formal policy adopted from time to time by the Company and
issued and promulgated to employees in writing. In the case of any employee on
an approved leave of absence, the Committee may make such provisions respecting
suspension of vesting of the Option while on leave from the employ of the
Company or a Subsidiary as it may deem appropriate, except that in no event may
an Option be exercised after the expiration of the term set forth in the Option
agreement. The Committee will have sole discretion to determine whether a
Participant has ceased to provide services and the effective date on which the
Participant ceased to provide services (the "Termination Date").

                                      -17-<PAGE>

                                                                  Exhibit 10.75

                            LEASE EXTENSION AGREEMENT

This agreement is dated June 26, 2000 for reference purposes and is an
additional modification to the current Lease Agreement dated November 30, 1990
between Charles A. Grant and Mark Greenberg (LESSOR) and Urnotech Calypte
Biomedical Corporation (LESSEE) for the property known as 1440 Fourth Street,
Berkeley, California.

Except as indicated below all other terms and conditions of the Lease
Agreement remain unchanged.

     1.       LEASE EXTENSION AND RENT PAYMENT. The lease is hereby extended
              four months through December 31, 2000. The lease payment for this
              extension will remain $27,000.00 per month.

     2.       HOLDING OVER. If LESSEE remains in possession of the premises per
              Paragraph 26 (Holding Over), then the agreed monthly rent is
              $29,000.

LESSOR                                           LESSEE

                                                 Calypte Biomedical Corporation

/s/ Charles A. Grant                             by    /s/ Nancy E. Katz
-----------------------------                        --------------------------
                                                       Nancy E. Katz

Title:  Partner (Gen)                            Title:   CEO, President, CFO
      -----------------------

Date:   6/28/00                                  Date:  6/26/00
      -----------------------                           -----------------------

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