Document:

EX-4.3

 Exhibit 4.3 
  

 
 

 
  
  

  
 

 

 

 
  

 TABLE OF CONTENTS 

 

							
	 	  	 	  	Page	 
	   PARTIES
	  		  	 	1	 
	   RECITALS
	  		  	 	1	 
	   Section 1.
	  	Certain Definitions	  			
	 (a)
	  	 ADR Register
	  	 	1	 
	 (b)
	  	 ADRs; Direct Registration ADRs
	  	 	1	 
	 (c)
	  	 ADS
	  	 	1	 
	 (d)
	  	 Beneficial Owner
	  	 	2	 
	 (e)
	  	 CSB
	  	 	2	 
	 (f)
	  	 Custodian
	  	 	2	 
	 (g)
	  	 Deliver, execute, issue et al.
	  	 	2	 
	 (h)
	  	 Delivery Order
	  	 	2	 
	 (i)
	  	 Deposited Securities
	  	 	2	 
	 (j)
	  	 Direct Registration System
	  	 	3	 
	 (k)
	  	 Holder
	  	 	3	 
	 (l)
	  	 Securities Act of 1933
	  	 	3	 
	 (m)
	  	 Securities Exchange Act of 1934
	  	 	3	 
	 (n)
	  	 Shares
	  	 	3	 
	 (o)
	  	 Transfer Office
	  	 	3	 
	 (p)
	  	 Withdrawal Order
	  	 	3	 
	   Section 2.
	  	Form of ADRs	  	 	3	 
	   Section 3.
	  	Deposit of Shares	  	 	4	 
	   Section 4.
	  	Issue of ADRs	  	 	5	 
	   Section 5.
	  	Distributions on Deposited Securities	  	 	5	 
	   Section 6.
	  	Withdrawal of Deposited Securities	  	 	6	 
	   Section 7.
	  	Substitution of ADRs	  	 	6	 
	   Section 8.
	  	Cancellation and Destruction of ADRs; Maintenance of Records	  	 	6	 
	   Section 9.
	  	The Custodian	  	 	6	 
	   Section 10.
	  	Lists of Holders	  	 	7	 
	   Section 11.
	  	Depositary’s Agents	  	 	7	 
	   Section 12.
	  	Resignation and Removal of the Depositary; Appointment of Successor Depositary	  	 	7	 
	   Section 13.
	  	Compliance with Securities Exchange of 1934 Reporting and other Requirements; Reports	  	 	8	 
	   Section 14.
	  	Additional Shares	  	 	9	 
	   Section 15.
	  	Indemnification	  	 	10	 
	   Section 16.
	  	Notices	  	 	12	 
	   Section 17.
	  	Counterparts	  	 	13	 
	   Section 18.
	  	No Third-Party Beneficiaries; Holders and Beneficial Owners as Parties; Binding Effect	  	 	13	 
	   Section 19.
	  	Severability	  	 	13	 
	   Section 20.
	  	Governing Law; Consent to Jurisdiction	  	 	13	 
	   Section 21.
	  	Agent for Service	  	 	15	 
	   Section 22.
	  	Waiver of Immunities	  	 	15	 
	   Section 23.
	  	Waiver of Jury Trial	  	 	16	 
	   Section 24.
	  	Notification of Interests	  	 	16	 
	   Section 25.
	  	Amendment and Restatement of Prior Deposit Agreement	  	 	17	 
	 TESTIMONIUM
	  	 	15	 

  
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	 SIGNATURES
	  	 	15	 

  
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 EXHIBIT A 

 

							
		  	 	Page	 
	 FORM OF FACE OF ADR
	  	 	A-1	 
	 Introductory Paragraph
	  	 	A-1	 
	 (1)
	    	Issuance of ADSs	  	 	A-2	 
	 (2)
	    	Withdrawal of Deposited Securities	  	 	A-3	 
	 (3)
	    	Transfers, Split-Ups and Combinations of ADRs	  	 	A-4	 
	 (4)
	    	Certain Limitations to Registration, Transfer etc.	  	 	A-4	 
	 (5)
	    	Liability of Holder or Beneficial Owner for Taxes, Duties and Other Charges	  	 	A-5	 
	 (6)
	    	Disclosure of Interests	  	 	A-6	 
	 (7)
	    	Charges of Depositary	  	 	A-7	 
	 (8)
	    	Available Information	  	 	A-10	 
	 (9)
	    	Execution	  	 	A-11	 
	 Signature of Depositary
	  	 	A-10	 
	 Address of Depositary’s Office
	  	 	A-10	 
	 FORM OF REVERSE OF ADR
	  	 	A-11	 
	 (10)
	    	Distributions on Deposited Securities	  	 	A-12	 
	 (11)
	    	Record Dates	  	 	A-13	 
	 (12)
	    	Voting of Deposited Securities	  	 	A-13	 
	 (13)
	    	Changes Affecting Deposited Securities	  	 	A-14	 
	 (14)
	    	Exoneration	  	 	A-15	 
	 (15)
	    	Resignation and Removal of Depositary; the Custodian	  	 	A-18	 
	 (16)
	    	Amendment	  	 	A-19	 
	 (17)
	    	Termination	  	 	A-20	 
	 (18)
	    	Appointment; Acknowledgements and Agreements	  	 	A-20	 
	 (19)
	    	Waiver	  	 	A-21	 
	 (20)
	    	Jurisdiction	  	 	A-22	 
	 (21)
	    	Elective Distributions in Cash or Shares	  	 	A-22	 

  
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 AMENDED AND RESTATED DEPOSIT AGREEMENT, dated as of _____________ __, 2021 (the “Deposit
Agreement”), among EVOTEC SE and its successors (the “Company”), JPMORGAN CHASE BANK, N.A., as depositary hereunder (the “Depositary”), and all Holders (as defined below) and Beneficial Owners (as defined
below) from time to time of American Depositary Receipts (“ADRs”) issued hereunder evidencing American Depositary Shares (“ADSs”) representing deposited Shares (as defined below). The Company hereby appoints the
Depositary as depositary for the Deposited Securities (as defined below) and hereby authorizes and directs the Depositary to act in accordance with the terms set forth in this Deposit Agreement. All capitalized terms used herein have the meanings
ascribed to them in Section 1 or elsewhere in this Deposit Agreement. 
 WHEREAS, the Company and the Depositary entered into a Deposit
Agreement, dated as of April 15, 2008, as amended by Amendment No. 1 thereto, dated as of December 30, 2010 (as previously amended, the “Prior Deposit Agreement”), for the purposes set forth therein, for the creation
of ADSs representing the Shares so deposited and for the execution and delivery of ADRs (“Prior Receipts”) evidencing the ADSs; 

WHEREAS, pursuant to the terms of the Prior Deposit Agreement, the Company and the Depositary wish to amend and restate the Prior Deposit Agreement and
the Prior Receipts; 
 NOW THEREFORE, in consideration of the premises, subject to Section 24 hereof, the parties hereto hereby amend and
restate the Prior Deposit Agreement and the Prior Receipts in their entirety as follows: 
 1. Certain Definitions. 

(a)      “ADR Register” is defined in paragraph (3) of the form of ADR (Transfers, Split-Ups and Combinations of ADRs). 
 (b)      “ADRs” mean the
American Depositary Receipts executed and delivered hereunder. ADRs may be either in physical certificated form or Direct Registration ADRs (as hereinafter defined). ADRs in physical certificated form, and the terms and conditions governing the
Direct Registration ADRs, shall be substantially in the form of Exhibit A annexed hereto (the “form of ADR”). The term “Direct Registration ADR” means an ADR, the ownership of which is recorded on the Direct
Registration System. References to “ADRs” shall include certificated ADRs and Direct Registration ADRs, unless the context otherwise requires. The form of ADR is hereby incorporated herein and made a part hereof; the provisions of the form
of ADR shall be binding upon the parties hereto. 
 (c)      Subject to paragraph (13) of the form of ADR
(Changes Affecting Deposited Securities), each “ADS” evidenced by an ADR represents the right to 

  
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receive, and to exercise the beneficial ownership interests in, the number of Shares specified in the form of ADR attached hereto as Exhibit A (as amended from time to time) that are on deposit
with the Depositary and/or the Custodian and a pro rata share in any other Deposited Securities, subject, in each case, to the terms of this Deposit Agreement and the ADSs. The
ADS(s)-to-Share(s) ratio is subject to amendment as provided in the form of ADR (which may give rise to fees contemplated in paragraph (7) thereof (Charges of
Depositary)). 
 (d)     “Beneficial Owner” means as to any ADS, any person or entity having a
beneficial ownership interest in such ADS. A Beneficial Owner need not be the Holder of the ADR evidencing such ADS. If a Beneficial Owner of ADSs is not a Holder, it must rely on the Holder of the ADR(s) evidencing such ADSs in order to assert any
rights or receive any benefits under this Deposit Agreement. The arrangements between a Beneficial Owner of ADSs and the Holder of the corresponding ADRs may affect the Beneficial Owner’s ability to exercise any rights it may have. 

(e)     “CSB” means Clearstream Banking AG, the German central securities depositary, and any successor
entity. 
 (f)      “Custodian” means the agent or agents of the Depositary (singly or collectively, as
the context requires) and any additional or substitute Custodian appointed pursuant to Section 9. 
 (g)     The terms
“deliver,” “execute,” “issue,” “register,” “surrender,” “transfer” or “cancel,” when used with respect to (i) Shares refers,
where the context requires, to an entry or entries or an electronic transfer or transfers in an account or accounts maintained by institutions authorized under applicable law to effect transfers of securities (which may include the CSB) and not to
the physical transfer of certificates representing the Shares and (ii) Direct Registration ADRs, shall refer to an entry or entries or an electronic transfer or transfers in the Direct Registration System, and, when used with respect to ADRs in
physical certificated form, shall refer to the physical delivery, execution, issuance, registration, surrender, transfer or cancellation of certificates representing the ADRs. 

(h)     “Delivery Order” is defined in Section 3. 

(i)      “Deposited Securities” as of any time means all Shares at such time deposited under this Deposit
Agreement and any and all other Shares, securities, property and cash at such time held by the Depositary or the Custodian in respect or in lieu of such deposited Shares and other Shares, securities, property and cash. Deposited Securities are not
intended to, and shall not, constitute proprietary assets of the Depositary, the Custodian or their nominees. Beneficial ownership in Deposited Securities is intended to be, and shall at all times during the term of the Deposit Agreement continue to
be, vested in the Beneficial Owners of the ADSs representing such Deposited Securities. 

  
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 (j)       “Direct Registration System” means the
system for the uncertificated registration of ownership of securities established by The Depository Trust Company (“DTC”) and utilized by the Depositary pursuant to which the Depositary may record the ownership of ADRs without the
issuance of a certificate, which ownership shall be evidenced by periodic statements issued by the Depositary to the Holders entitled thereto. For purposes hereof, the Direct Registration System shall include access to the Profile Modification
System maintained by DTC, which provides for automated transfer of ownership between DTC and the Depositary. 

(k)      “Holder” means the person or persons in whose name an ADR is registered on the ADR Register. For
all purposes under the Deposit Agreement and the ADRs, a Holder shall be deemed to have all requisite authority to act on behalf of any and all Beneficial Owners of the ADSs evidenced by the ADR(s) registered in such Holder’s name. 

(l)       “Securities Act of 1933” means the United States Securities Act of 1933, as from time to
time amended. 
 (m)     “Securities Exchange Act of 1934” means the United States Securities Exchange Act
of 1934, as from time to time amended. 
 (n)      “Shares” mean the ordinary bearer shares, as amended
or redenominated from time to time, of the Company, and shall include the rights to receive Shares specified in paragraph (1) of the form of ADR (Issuance of ADSs). 

(o)      “Transfer Office” is defined in paragraph (3) of the form of ADR (Transfers, Split-Ups and Combinations of ADRs). 
 (p)      “Withdrawal
Order” is defined in Section 6. 
 2.  Form of ADRs. 

(a)      Direct Registration ADRs. Notwithstanding anything in this Deposit Agreement or in the form of ADR to the
contrary, ADSs shall be evidenced by Direct Registration ADRs, unless certificated ADRs are specifically requested by the Holder. 

(b)      Certificated ADRs. ADRs in certificated form shall be printed or otherwise reproduced at the discretion of
the Depositary in accordance with its customary practices in its American depositary receipt business, or at the request of the Company typewritten and photocopied on plain or safety paper, and shall be substantially in the form set forth in the
form of ADR, with such changes as may be required by the Depositary or the Company to comply with their obligations hereunder, any applicable law, regulation or usage or to indicate any special limitations or restrictions to which any particular
ADRs are subject. ADRs may be 

  
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issued in denominations of any number of ADSs. ADRs in certificated form shall be executed by the Depositary by the manual or facsimile signature of a duly authorized officer of the Depositary.
ADRs in certificated form bearing the facsimile signature of anyone who was at the time of execution a duly authorized officer of the Depositary shall bind the Depositary, notwithstanding that such officer has ceased to hold such office prior to the
delivery of such ADRs. 
 (c)      Binding Effect. Holders of ADRs, and the Beneficial Owners of the ADSs
evidenced by such ADRs, shall each be bound by the terms and conditions of this Deposit Agreement and of the form of ADR, regardless of whether such ADRs are Direct Registration ADRs or certificated ADRs. 

3.  Deposit of Shares. 

(a)      Requirements. Shares may be deposited under this Deposit Agreement by delivery thereof to the Custodian,
at the account maintained by the Custodian for such purpose at the CSB. Shares or evidence of rights to receive Shares may be deposited through (x) the electronic transfer of such Shares to the account maintained by the Custodian for such
purpose at the CSB, (y) evidence satisfactory to the Custodian of irrevocable instructions to cause such Shares to be transferred to such account or (z) delivery of certificates representing such Shares. If use of the CSB book-entry system
in connection with the ADSs is discontinued at any time for any reason, the Company shall make such other book-entry arrangements as may be reasonably requested by the Depositary. In connection with the deposit of Shares hereunder, the Depositary or
the Custodian may require the following in a form satisfactory to it: 
 (i)        a written
order directing the Depositary to issue to, or upon the written order of, the person or persons designated in such order a Direct Registration ADR or ADRs evidencing the number of ADSs representing such deposited Shares (a “Delivery
Order”); 
 (ii)       proper endorsements or duly executed instruments of transfer in
respect of such deposited Shares; 
 (iii)      instruments assigning to the Depositary, the Custodian
or a nominee of either any distribution on or in respect of such deposited Shares or indemnity therefor; and 

(iv)      proxies entitling the Custodian to vote such deposited Shares. 

(b)      Registration of Deposited Securities. As soon as practicable after the Custodian receives Deposited
Securities pursuant to any such deposit or pursuant to paragraph (10) (Distributions on Deposited Securities) or (13) (Changes Affecting Deposited Securities) of the form of ADR, the Custodian shall present such Deposited

  
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Securities for registration of transfer into the name of the Depositary, the Custodian or a nominee of either, in each case for the benefit of Holders, to the extent such registration is
practicable, at the cost and expense of the person making such deposit (or for whose benefit such deposit is made) and shall obtain evidence satisfactory to it of such registration. Deposited Securities shall be held by the Custodian for the account
and to the order of the Depositary for the benefit of Holders of ADRs (to the extent not prohibited by law) at its account at CSB (to the extent eligible for deposit with CSB) or at such other place or places and in such manner as the Depositary
shall determine. Notwithstanding anything else contained herein, in the form of ADR and/or in any outstanding ADSs, the Depositary, the Custodian and their respective nominees are intended to be, and shall at all times during the term of the Deposit
Agreement be, the record holder(s) only of the Deposited Securities represented by the ADSs for the benefit of the Holders. The Depositary, on its own behalf and on behalf of the Custodian and their respective nominees, disclaims any beneficial
ownership interest in the Deposited Securities held on behalf of the Holders. 
 (c)      Delivery of Deposited
Securities. Deposited Securities may be delivered by the Custodian to any person only under the circumstances expressly contemplated in this Deposit Agreement. To the extent that the provisions of or governing the Shares make delivery of
certificates therefor impracticable, Shares may be deposited hereunder by such delivery thereof as the Depositary or the Custodian may reasonably accept, including, without limitation, by causing them to be credited to an account maintained by the
Custodian for such purpose with the Company or an accredited intermediary, such as a bank, acting as a registrar for the Shares, together with delivery of the documents, payments and Delivery Order referred to herein to the Custodian or the
Depositary. 
 4.  Issue of ADRs. After any such deposit of Shares, the Custodian shall notify the Depositary of such deposit and of
the information contained in any related Delivery Order by letter, first class airmail postage prepaid, or, at the request, risk and expense of the person making the deposit, by SWIFT, cable, telex, email or facsimile transmission. After receiving
such notice from the Custodian, the Depositary, subject to this Deposit Agreement, shall properly issue at the Transfer Office, to or upon the order of any person named in such notice, an ADR or ADRs registered as requested and evidencing the
aggregate ADSs to which such person is entitled. 
 5.  Distributions on Deposited Securities. To the extent that the Depositary
determines in its discretion that any distribution pursuant to paragraph (10) of the form of ADR (Distributions on Deposited Securities) is not practicable with respect to any Holder, the Depositary may (after consultation with the
Company if practicable in the case where the Depositary believes such distribution is not practicable with respect to all Holders) make such distribution as it so deems practicable, including the distribution of foreign currency, securities or
property (or appropriate documents evidencing the right to receive foreign currency, securities or property) or the 

  
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retention thereof as Deposited Securities with respect to such Holder’s ADRs (without liability for interest thereon or the investment thereof). 

6.  Withdrawal of Deposited Securities. In connection with any surrender of an ADR for withdrawal of the Deposited Securities
represented by the ADSs evidenced thereby, the Depositary may require proper endorsement in blank of such ADR (or duly executed instruments of transfer thereof in blank) and the Holder’s written order directing the Depositary to cause the
Deposited Securities represented by the ADSs evidenced by such ADR to be withdrawn and delivered to, or upon the written order of, any person designated in such order (a “Withdrawal Order”). Directions from the Depositary to the
Custodian to deliver Deposited Securities shall be given by letter, first class airmail postage prepaid, or, at the request, risk and expense of the Holder, by SWIFT, cable, telex, email or facsimile transmission. Delivery of Deposited Securities
may be made by the delivery of certificates (which, if required by law shall be properly endorsed or accompanied by properly executed instruments of transfer or, if such certificates may be registered, registered in the name of such Holder or as
ordered by such Holder in any Withdrawal Order) or by such other means as the Depositary may deem practicable, including, without limitation, by transfer of record ownership thereof to an account designated in the Withdrawal Order maintained either
by the Company or an accredited intermediary, such as a bank, acting as a registrar for the Deposited Securities. The Company agrees to cooperate with the Depositary and any registrar of the Deposited Securities in order to effectuate the withdrawal
and transfer of the Deposited Securities upon any cancellation of ADRs by Holders and/or Beneficial Owners thereof. 
 7.  Substitution
of ADRs. The Depositary shall execute and deliver a new Direct Registration ADR in exchange and substitution for any mutilated certificated ADR upon cancellation thereof or in lieu of and in substitution for such destroyed, lost or stolen
certificated ADR, unless the Depositary has notice that such ADR has been acquired by a bona fide purchaser, upon the Holder thereof filing with the Depositary a request for such execution and delivery and a sufficient indemnity bond and satisfying
any other reasonable requirements imposed by the Depositary. 
 8.  Cancellation and Destruction of ADRs; Maintenance of Records. All
ADRs surrendered to the Depositary shall be cancelled by the Depositary. The Depositary is authorized to destroy ADRs in certificated form so cancelled in accordance with its customary practices. The Depositary agrees to maintain or cause its agents
to maintain records of all ADRs surrendered and Deposited Securities withdrawn under Section 6 hereof and paragraph (2) of the form of ADR (Withdrawal of Deposited Securities), substitute ADRs delivered under Section 7 hereof,
and canceled or destroyed ADRs under this Section 8, in keeping with the procedures ordinarily followed by stock transfer agents located in the United States or as required by the laws or regulations governing the Depositary. 

9.  The Custodian. 

  
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 (a)      Rights of the Depositary. Any Custodian in acting
hereunder shall be subject to the directions of the Depositary and shall be responsible solely to it. The Depositary reserves the right to add, replace or remove a Custodian. The Depositary will give prompt, written notice of any such action, which
will be advance notice if practicable. The Depositary may discharge any Custodian at any time upon notice to the Custodian being discharged. 

(b)      Rights of the Custodian. Any Custodian may resign from its duties hereunder by providing at least 30
days’ prior written notice to the Depositary. Any Custodian ceasing to act hereunder as Custodian shall deliver, upon the instruction of the Depositary, all Deposited Securities held by it to a Custodian continuing to act. 

(c)      Notwithstanding anything to the contrary contained in this Deposit Agreement (including the ADRs) and, subject to
the further limitations set forth in clause (o) of paragraph (14) of the form of ADR (Exoneration), the Depositary shall not be responsible for, and shall incur no liability in connection with or arising from, any act or omission to
act on the part of the Custodian except to the extent that any Holder has incurred liability directly as a result of the Custodian having (i) committed fraud or willful misconduct in the provision of custodial services to the Depositary or
(ii) failed to use reasonable care in the provision of custodial services to the Depositary as determined in accordance with the standards prevailing in the jurisdiction in which the Custodian is located. 

10.  Lists of Holders. The Company shall have the right to inspect transfer records of the Depositary and its agents and the ADR
Register, take copies thereof and require the Depositary and its agents to supply copies of such portions of such records as the Company may request. The Depositary or its agents shall furnish to the Company promptly upon the written request of the
Company, a list of the names, addresses and holdings of ADSs by all Holders as of a date within seven days of the Depositary’s receipt of such request. 

11.  Depositary’s Agents. The Depositary may perform its obligations under this Deposit Agreement through any agent appointed by
it, provided that the Depositary shall notify the Company of such appointment and shall remain responsible for the performance of such obligations as if no agent were appointed, subject to paragraph (14) of the form of ADR (Exoneration).

 12.  Resignation and Removal of the Depositary; Appointment of Successor Depositary. 

(a)      Resignation of the Depositary. The Depositary may at any time resign as Depositary hereunder by
written notice of its election to do so delivered to the Company, such resignation to take effect upon the appointment of a successor depositary and its acceptance of such appointment as hereinafter provided. 

  
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 (b)      Removal of the Depositary. The Depositary may at any time
be removed by the Company by providing no less than 60 days’ prior written notice of such removal to the Depositary, such removal to take effect on the later of (i) the 60th day after
such notice of removal is first provided and (ii) the appointment of a successor depositary and its acceptance of such appointment as hereinafter provided. Notwithstanding the foregoing, if upon the resignation or removal of the Depositary a
successor depositary is not appointed within the applicable 60-day period as specified in paragraph (17) of the form of ADR (Termination), then the Depositary may elect to terminate this Deposit Agreement and the ADR and the provisions
of said paragraph (17) shall thereafter govern the Depositary’s obligations hereunder. 

(c)      Appointment of Successor Depositary. In case at any time the Depositary acting hereunder shall resign or
be removed, the Company shall use its reasonable best efforts to appoint a successor depositary, which shall be a bank or trust company having an office in the Borough of Manhattan, The City of New York. Every successor depositary shall execute and
deliver to its predecessor and to the Company an instrument in writing accepting its appointment hereunder, and thereupon such successor depositary, without any further act or deed, shall become fully vested with all the rights, powers, duties and
obligations of its predecessor. The predecessor depositary, only upon payment of all sums due to it and on the written request of the Company, shall (i) execute and deliver an instrument transferring to such successor all rights and powers of
such predecessor hereunder (other than its rights to indemnification and fees owing, each of which shall survive any such removal and/or resignation), (ii) duly assign, transfer and deliver all right, title and interest to the Deposited
Securities to such successor, and (iii) deliver to such successor a list of the Holders of all outstanding ADRs. Any such successor depositary shall promptly mail notice of its appointment to such Holders. Any bank or trust company into or with
which the Depositary may be merged or consolidated, or to which the Depositary shall transfer substantially all its American depositary receipt business, shall be the successor of the Depositary without the execution or filing of any document or any
further act. 
 13.  Compliance with Securities Exchange Act of 1934 Reporting and Other Requirements; Reports. 

(a)      Securities Exchange Act of 1934. The Company is subject to the periodic reporting requirements of the
Securities Exchange Act of 1934 and accordingly files certain reports with the Securities Exchange Commission (the “Commission”). Such reports and other information can be inspected and retrieved by Holders and Beneficial Owners
through the Commission’s EDGAR system on the Commission’s Internet Web site located at the date of this Deposit Agreement at www.sec.gov and can be inspected and copied at public reference facilities maintained by the Commission located at
the date of this Deposit Agreement at 100 F Street, NE, Washington, DC 20549. The Company represents and warrants that as of 

  
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the date of the Deposit Agreement, it is in compliance with the registration, reporting and other requirements of the Securities Exchange Act of 1934 and hereby covenants and agrees to publish
and file all reports, and to take all other actions, necessary and/or required to remain in compliance with the registration, reporting and other requirements of the Securities Exchange Act of 1934 as and when required at all times hereafter in
order to remain in compliance with such registration, reporting and other requirements. The Company agrees to promptly notify the Depositary in the event of any change in the truth of any such representations, warranties, covenants and agreements.
The Company, and each Holder and Beneficial Owner of an ADR and/or an interest therein by so holding or owning an ADR and/or an interest therein, acknowledges and agrees that the Depositary does not assume any duty or responsibility to
determine if the Company is in compliance with the current registration, reporting and other requirements of the Securities Exchange Act of 1934 or to take any action if the Company is not complying with those requirements, and (ii) the
Depositary is relying solely on the representations, warranties, covenants and agreements of the Company in this Section 13(a) and paragraph (8) (Available Information) of the Form of ADR in connection therewith and may, and is expressly
authorized by the Company and each Holder and Beneficial Owner of an ADR and/or an interest therein to, so rely on, and represent, warrant and certify that the Company is compliant with the registration, reporting and other requirements of the
Securities Exchange Act of 1934 based on such representations, warranties, covenants and agreements of the Company. 

(b)      Reports. On or before the first date on which the Company makes any communication available to Holders of
Deposited Securities or any securities regulatory authority or stock exchange, by publication or otherwise that could reasonably be expected to affect or impact the ADRs, the ADSs, Deposited Securities or the respective holders thereof, including
without limitation, the rights, benefits, duties and/or obligations with respect to the Depositary and the Company thereto, the Company shall transmit to the Depositary a copy thereof in English or with an English translation or summary. The Company
has delivered to the Depositary, the Custodian and any Transfer Office a copy of all provisions of or governing the Shares and any other Deposited Securities issued by the Company or any affiliate of the Company and, promptly upon any change
thereto, the Company shall deliver to the Depositary, the Custodian and any Transfer Office a copy (in English or with an English translation) of such provisions as so changed. The Depositary and its agents may rely upon the Company’s delivery
of all such communications, information and provisions for all purposes of this Deposit Agreement and the Depositary shall have no liability for the accuracy or completeness of any thereof. 

14. Additional Shares. The Company agrees with the Depositary that neither the Company nor any company controlling, controlled by or under common
control with the Company shall (a) issue (i) additional Shares, (ii) rights to subscribe for 

  
 9 

 

 
  

 
Shares, (iii) securities convertible into or exchangeable for Shares or (iv) rights to subscribe for any such securities or (b) deposit any Shares under this Deposit Agreement,
except, in each case, under circumstances complying in all respects with the Securities Act of 1933. At the reasonable request of the Depositary where it deems necessary, the Company will furnish the Depositary with legal opinions, in forms and from
counsels reasonably acceptable to the Depositary. The Depositary will not knowingly accept for deposit hereunder any Shares required to be registered under the Securities Act of 1933 unless a registration statement is in effect and will use
reasonable efforts to comply with written instructions of the Company not to accept for deposit hereunder any Shares identified in such instructions at such times and under such circumstances as may reasonably be specified in such instructions in
order to facilitate the Company’s compliance with the requirements of the securities laws, rules and regulations in the United States. 

15.  Indemnification. 

(a)      Indemnification by the Company. The Company shall indemnify, defend and hold harmless each of the
Depositary, the Custodian and their respective directors, officers, employees, agents and affiliates against any loss, liability or expense (including reasonable fees and expenses of counsel) that may arise out of acts performed or omitted, in
connection with the provisions of this Deposit Agreement and of the ADRs, as the same may be amended, modified or supplemented from time to time in accordance herewith (i) by either the Depositary or a Custodian or their respective directors,
officers, employees, agents and affiliates, except for any liability or expense directly arising out of the negligence or willful misconduct of the Depositary or its directors, officers, or affiliates acting in their capacities as such hereunder, or
(ii) by the Company or any of its directors, officers, employees, agents and affiliates, including, without limitation, if any of the representations and warranties of the Company contained in Section 13 hereof and/or paragraph 8 of the
Form of ADR (Available Information) were or are incorrect in any respect and/or if the Company violates or breaches any of its covenants or agreements contained therein with respect to the Securities Exchange Act of 1934 or otherwise. 

The indemnities set forth in the preceding paragraph shall also apply to any liability or expense that may arise out of any misstatement or alleged
misstatement or omission or alleged omission in any registration statement, proxy statement, prospectus (or placement memorandum), or preliminary prospectus (or preliminary placement memorandum) relating to the offer, issuance, withdrawal or sale of
ADSs or the deposit, withdrawal, offer or sale of Shares, except to the extent any such liability or expense arises out of (i) information relating to the Depositary or its agents (other than the Company), as applicable, furnished in writing by
the Depositary expressly for use in any of the foregoing documents and not changed or altered by the Company or any other person (other than the Depositary) or (ii) if such information is provided, the failure to state a material fact therein
necessary to make the information provided, in light of the circumstances under which provided, not 

  
 10 

 

 
  

 
misleading. 
 (b)      Indemnification by the Depositary.
Subject to the limitations provided for in Sections 9 and 15(c) below, the Depositary shall indemnify, defend and hold harmless the Company against any direct loss, liability or expense (including reasonable fees and expenses of counsel) incurred by
the Company in respect of this Deposit Agreement to the extent such loss, liability or expense is due to the negligence or willful misconduct of the Depositary. 

(c)      Damages or Lost Profits. Notwithstanding any other provision of this Deposit Agreement or the ADRs to the
contrary, neither the Depositary nor the Company, nor any of their respective agents shall be liable to the other for any indirect, special, punitive or consequential damages (excluding reasonable fees and expenses of counsel) or lost profits, in
each case of any form (collectively, “Special Damages”) incurred by any of them, or liable to any other person or entity (including, without limitation, Holders and Beneficial Owners) for any Special Damages, or any fees or expenses
of counsel in connection therewith, whether or not foreseeable and regardless of the type of action in which such a claim may be brought; provided, however, that (i) notwithstanding the foregoing and, for the avoidance of doubt, the Depositary
and its agents shall be entitled to legal fees and expenses in defending against any claim for Special Damages and (ii) to the extent Special Damages arise from or out of a claim brought by a third party (including, without limitation, Holders
and Beneficial Owners) against the Depositary or any of its agents, the Depositary and its agents shall be entitled to full indemnification from the Company for all such Special Damages, and reasonable fees and expenses of counsel in connection
therewith, unless such Special Damages are found to have been a direct result of the gross negligence or willful misconduct of the Depositary. 

(d)      Notification. In case any proceeding shall be instituted involving any person in respect of which
indemnity may be sought under this Section 15, such person (an “indemnified person”) shall notify the person from whom it is seeking indemnification (the “indemnifying person”) as promptly as reasonably
practicable of the commencement of any indemnifiable action or claim promptly after such indemnified person becomes aware of such commencement; provided, however, that the failure to notify the indemnifying party shall not relieve the
indemnifying party from liability that it may have under this Section 15 except and only to the limited extent the indemnifying person is materially prejudiced by such failure through the forfeiture of substantive rights or defenses) by such
failure; and provided, further, that the failure to notify the indemnifying party shall not relieve the indemnifying party from any liability that it may have to an indemnified party otherwise than under this Section 15. No indemnifying
person shall be liable for any settlement of any proceeding effected without its written consent (which consent shall not be unreasonably withheld, delayed or conditioned), but if settled with such indemnifying 

  
 11 

 

 
  

 
person’s written consent or if there is a final and non-appealable judgment by a court of competent jurisdiction in any such proceeding, the
indemnifying person agrees to indemnify and hold harmless each indemnified person from and against any and all losses, claims, damages, liabilities and reasonable and documented legal or other out-of-pocket expenses by reason of such settlement or judgment in accordance with and to the extent provided in the other provisions herein. No indemnifying person shall, without the prior
written consent of any indemnified person, effect any settlement of any pending or threatened proceedings in respect of which indemnity could have been sought hereunder by such indemnified person unless such settlement (i) includes an
unconditional release of such indemnified person in form and substance reasonably satisfactory to such indemnified person from all liability or claims that are the subject matter of such proceedings and (ii) does not include any statement as to
or any admission of fault, culpability, wrong doing or a failure to act by or on behalf of any indemnified person. 

(e)      Survival. The obligations set forth in this Section 15 shall survive the termination of this Deposit
Agreement and the succession or substitution of any indemnified person. 
 16.  Notices. 

(a)      Notice to Holders. Notice to any Holder shall be deemed given when first mailed, first class
postage prepaid, to the address of such Holder on the ADR Register or received by such Holder. Failure to notify a Holder or any defect in the notification to a Holder shall not affect the sufficiency of notification to other Holders or to the
Beneficial Owners of the ADSs evidenced by the ADRs held by such other Holders. Except as otherwise provided elsewhere in the Deposit Agreement, the Depositary’s only notification obligations under this Deposit Agreement and the ADRs shall be
to Holders, and the Depositary shall have no notification obligations otherwise to Beneficial Owners. The foregoing shall not affect any notification obligations the Depositary has to the Company as provided in this Deposit Agreement. Notice to a
Holder shall be deemed, for all purposes of the Deposit Agreement and the ADRs, to constitute notice to any and all Beneficial Owners of the ADSs evidenced by such Holder’s ADRs. 

(b)      Notice to the Depositary or the Company. Notice to the Depositary or the Company shall be deemed
given when first received by it at the address or by electronic transmission to the e-mail address set forth in (i) or (ii), respectively, or at such other address or email address provided by the
Depositary or the Company to the other, respectively, in the same manner as notices are required to be provided in this Section 16: 
  

	 	(i)	 JPMorgan Chase Bank, N.A. 

383 Madison Avenue, Floor 11 
 New York, New York,
10179 

  
 12 

 

 
  

 Attention: Depositary Receipts Group 

E-mail Address:
DR_Global_CSM@jpmorgan.com 
  

	 	(ii)	 Evotec SE 

Essener Bogen 7 
 22419 Hamburg, Germany 

Attention: Dr. Christian Dargel, EVP Global Head of Legal & Compliance (General Counsel) 

E-mail Address: Christian.Dargel@evotec.com 

Delivery of a notice by means of electronic messaging shall be deemed to be effective at the time of the initiation of the transmission by the sender
(as shown on the sender’s records) to the email address set forth above, notwithstanding that the intended recipient retrieves the message at a later date, fails to retrieve such message, or fails to receive such notice on account of its
failure to maintain the designated e-mail address, its failure to designate a substitute e-mail address or for any other reason. 

17.  Counterparts. This Deposit Agreement may be executed in any number of counterparts, each of which shall be deemed an original and
all of which shall constitute one instrument. Delivery of an executed signature page of this Deposit Agreement by facsimile or other electronic transmission (including “.pdf”, “.tif” or similar format) shall be effective as
delivery of a manually executed counterpart hereof. 
 18.  No Third-Party Beneficiaries; Holders and Beneficial Owners as Parties;
Binding Effect. This Deposit Agreement is for the exclusive benefit of the Company, the Depositary and the Holders and their respective successors hereunder, and, except to the extent specifically set forth in Section 15 of this Deposit
Agreement, shall not give any legal or equitable right, remedy or claim whatsoever to any other person. The Holders and Beneficial Owners from time to time shall be parties to this Deposit Agreement and shall be bound by all of the provisions
hereof. A Beneficial Owner shall only be able to exercise any right or receive any benefit hereunder solely through the Holder of the ADR(s) evidencing the ADSs owned by such Beneficial Owner. 

19.  Severability. If any provision contained in this Deposit Agreement or in the ADRs is, or becomes, invalid, illegal or
unenforceable in any respect, the remaining provisions contained herein and therein shall in no way be affected thereby. 

20.  Governing Law; Consent to Jurisdiction. 

(a)      Governing Law. The Deposit Agreement, the ADSs and the ADRs shall be governed by and construed in
accordance with the internal laws of the State of New 

  
 13 

 

 
  

 
York without giving effect to the application of the conflict of law principles thereof. 

(b)      By the Company. The Company irrevocably agrees that any legal suit, action or proceeding against or
involving the Company brought by the Depositary or any Holder or Beneficial Owner, arising out of or based upon this Deposit Agreement, the ADSs, the ADRs or the transactions contemplated herein, therein, hereby or thereby, may be instituted in any
state or federal court in New York, New York, and irrevocably waives any objection which it may now or hereafter have to the laying of venue of any such proceeding, and irrevocably submits to the non-exclusive
jurisdiction of such courts in any such suit, action or proceeding. The Company also irrevocably agrees that any legal suit, action or proceeding against or involving the Depositary brought by the Company, arising out of or based upon this Deposit
Agreement, the ADSs, the ADRs or the transactions contemplated herein, therein, hereby or thereby, may be instituted only in a state or federal court in New York, New York. 

(c)      By Holders and Beneficial Owners. By holding or owning an ADR or ADS or an interest therein, Holders and
Beneficial Owners each irrevocably agree that any legal suit, action or proceeding against or involving Holders or Beneficial Owners brought by the Company or the Depositary, arising out of or based upon this Deposit Agreement, the ADSs, the ADRs or
the transactions contemplated herein, therein, hereby or thereby, may be instituted in a state or federal court in New York, New York, and by holding or owning an ADR or ADS or an interest therein each irrevocably waives any objection which it may
now or hereafter have to the laying of venue of any such proceeding, and irrevocably submits to the non-exclusive jurisdiction of such courts in any such suit, action or proceeding. By holding or owning an ADR
or ADS or an interest therein, Holders and Beneficial Owners each also irrevocably agree that any legal suit, action or proceeding against or involving the Depositary and/or the Company brought by Holders or Beneficial Owners, arising out of or
based upon this Deposit Agreement, the ADSs, the ADRs or the transactions contemplated herein, therein, hereby or thereby, including, without limitation, claims under the Securities Act of 1933, may be instituted only in the United States District
Court for the Southern District of New York (or in the state courts of New York County in New York if either (i) the United States District Court for the Southern District of New York lacks subject matter jurisdiction over a particular dispute
or (ii) the designation of the United States District Court for the Southern District of New York as the exclusive forum for any particular dispute is, or becomes, invalid, illegal or unenforceable). 

(d)      Notwithstanding the foregoing or anything in this Deposit Agreement to the contrary, any suit, action or
proceeding against the Company based on this Deposit Agreement, the ADSs, the ADRs or the transactions contemplated herein, therein, hereby or thereby, may be instituted by the Depositary in any competent court in the Federal Republic of Germany,
the European Union, the United States and/or any other court of competent jurisdiction. 

  
 14 

 

 
  

 21.  Agent for Service. 

(a)      Appointment. The Company has appointed Evotec (US) Inc., 303B College Road, East Princeton, New Jersey
08540, as its authorized agent (the “Authorized Agent”) upon which process may be served in any such suit, action or proceeding arising out of or based on this Deposit Agreement, the ADSs, the ADRs or the transactions contemplated
herein, therein, hereby or thereby which may be instituted in any state or federal court in New York, New York by the Depositary or any Holder, and waives any other requirements of or objections to personal jurisdiction with respect thereto. Subject
to the Company’s rights to replace the Authorized Agent with another entity in the manner required were the Authorized Agent to have resigned, such appointment shall be irrevocable. 

(b)      Agent for Service of Process. The Company represents and warrants that the Authorized Agent has agreed to
act as said agent for service of process, and the Company agrees to take any and all action, including the filing of any and all documents and instruments, that may be necessary to continue such appointment in full force and effect as aforesaid. The
Company further hereby irrevocably consents and agrees to the service of any and all legal process, summons, notices and documents in any suit, action or proceeding against the Company, by service by mail of a copy thereof upon the Authorized Agent
(whether or not the appointment of such Authorized Agent shall for any reason prove to be ineffective or such Authorized Agent shall fail to accept or acknowledge such service), with a copy mailed to the Company by registered or certified air mail,
postage prepaid, to its address provided in Section 16(b) hereof. The Company agrees that the failure of the Authorized Agent to give any notice of such service to it shall not impair or affect in any way the validity of such service or any
judgment or award rendered in any suit, action or proceeding based thereon. If, for any reason, the Authorized Agent named above or its successor shall no longer serve as agent of the Company to receive service of process, notice or papers in New
York, the Company shall promptly appoint a successor that is a legal entity with offices in New York, New York, so as to serve and will promptly advise the Depositary thereof. 

(c)      Waiver of Personal Service of Process. In the event the Company fails to continue such designation and
appointment in full force and effect, the Company hereby waives personal service of process upon it and consents that any such service of process may be made by certified or registered mail, return receipt requested, directed to the Company at its
address last specified for notices hereunder, and service so made shall be deemed completed five (5) days after the same shall have been so mailed. 

22.  Waiver of Immunities. To the extent that the Company or any of its properties, assets or revenues may have or may hereafter be
entitled to, or have attributed to it, any right of immunity, on the grounds of sovereignty or otherwise, from any legal action, suit or proceeding, from the giving of any relief in any respect 

  
 15 

 

 
  

 
thereof, from setoff or counterclaim, from the jurisdiction of any court, from service of process, from attachment upon or prior to judgment, from attachment in aid of execution or judgment, or
from execution of judgment, or other legal process or proceeding for the giving of any relief or for the enforcement of any judgment, in any jurisdiction in which proceedings may at any time be commenced, with respect to its obligations, liabilities
or other matters under or arising out of or in connection with the Shares or Deposited Securities, the ADSs, the ADRs or this Deposit Agreement, the Company, to the fullest extent permitted by law, hereby irrevocably and unconditionally waives, and
agrees not to plead or claim, any such immunity and consents to such relief and enforcement. 
 23.  Waiver of Jury Trial. EACH PARTY
TO THIS DEPOSIT AGREEMENT (INCLUDING, FOR AVOIDANCE OF DOUBT, EACH HOLDER AND BENEFICIAL OWNER OF, AND/OR HOLDER OF INTERESTS IN, ADSS OR ADRS) HEREBY IRREVOCABLY WAIVES, TO THE FULLEST EXTENT PERMITTED BY APPLICABLE LAW, ANY RIGHT IT MAY HAVE TO A
TRIAL BY JURY IN ANY SUIT, ACTION OR PROCEEDING AGAINST THE DEPOSITARY AND/OR THE COMPANY DIRECTLY OR INDIRECTLY ARISING OUT OF, BASED ON OR RELATING IN ANY WAY TO THE SHARES OR OTHER DEPOSITED SECURITIES, THE ADSs OR THE ADRs, THE DEPOSIT AGREEMENT
OR ANY TRANSACTION CONTEMPLATED HEREIN OR THEREIN, OR THE BREACH HEREOF OR THEREOF (WHETHER BASED ON CONTRACT, TORT, COMMON LAW OR ANY OTHER THEORY), INCLUDING, WITHOUT LIMITATION, ANY SUIT, ACTION, CLAIM OR PROCEEDING UNDER THE UNITED STATES
FEDERAL SECURITIES LAWS. No provision of this Deposit Agreement or any ADR is intended to constitute a waiver or limitation of any rights which a Holder or any Beneficial Owner may have under the Securities Act of 1933 or the Securities Exchange Act
of 1934, to the extent applicable. 
 24.  Notification of Interests. In order to enable the Depositary to comply with any reporting
obligations it might have pursuant to applicable provisions of German law and the Company’s Articles of Association regarding the notification of such person’s interest in Shares, which provisions at the date of the Deposit Agreement
include Sections 33 and 34 of the Securities Trading Act (Wertpapierhandelsgesetz), the Company agrees to provide the Depositary with a written notice promptly at each such time the total number of the outstanding Shares or voting rights
change. Promptly after receipt thereof, the Depositary agrees to notify the Company of the number of Shares held by it hereunder. To the extent that the number of Shares notified to the Company by the Depositary in accordance with (ii) would
require the Depositary to file or submit a report and/or notice, or to the extent a report and/or notice has been previously filed or submitted, a further report and/or notice, in each case under German law and/or the Company’s Articles of
Association, the Company shall promptly provide the Depositary with the form of report and/or notice required to be submitted and/or filed, along with instructions as to how, when and where to submit each such report and/or notice. 

  
 16 

 

 
  

 25.  Amendment and Restatement of Prior Deposit Agreement. The Deposit Agreement
amends and restates the Prior Deposit Agreement in its entirety to consist exclusively of the Deposit Agreement, and each Prior Receipt is hereby deemed amended and restated to substantially conform to the form of ADR set forth in Exhibit A annexed
hereto, except that, to the extent any portion of such amendment and restatement impose or increase any fees or charges different from those set forth herein (other than charges in connection with foreign exchange control regulations, and taxes and
other governmental charges, delivery and other such expenses), or otherwise materially prejudice any substantial existing right of Holders of Prior Receipts or Beneficial Owners of ADSs evidenced by such Prior Receipt, such portion shall not become
effective as to such Holders or Beneficial Owners with respect to such Prior Receipt until 30 days after such Holders or Beneficial Owners shall have received notice thereof, such notice to be conclusively deemed given upon the mailing to such
Holders or Beneficial Owners of notice of such amendment and restatement which notice contains a provision whereby such Holders or Beneficial Owners can receive a copy of the form of ADR. 

[Signature page follows] 

  
 17 

 

 
  

 IN WITNESS WHEREOF, EVOTEC SE and JPMORGAN CHASE BANK, N.A. have duly executed this Deposit Agreement
as of the day and year first above set forth and all Holders and Beneficial Owners shall become parties hereto upon acceptance by them of ADSs issued in accordance with the terms hereof, or upon acquisition of any beneficial interest therein. 

 

			
	EVOTEC SE
		
	By:	 	  

		 	Name:
		 	Title:
	
	JPMORGAN CHASE BANK, N.A.
		
	By:	 	  

		 	Name:
		 	Title:

  
 [Signature Page to Deposit
Agreement] 

 

 
  

 EXHIBIT A 

ANNEXED TO AND INCORPORATED IN 
 DEPOSIT
AGREEMENT 
 [FORM OF FACE OF ADR] 
 CERTAIN
RIGHTS OF THE HOLDER OF THIS AMERICAN DEPOSITARY RECEIPT MAY BE WITHHELD IN ACCORDANCE WITH THE PROVISIONS OF PARAGRAPH (6) HEREOF, INCLUDING, WITHOUT LIMITATION, VOTING RIGHTS AND THE RIGHT TO RECEIVE DIVIDENDS AND OTHER DISTRIBUTIONS.

  

			
	        	 	 No. of ADSs:

	Number	 	

 Each ADS represents One-Half (1/2) of One Share 

CUSIP: 
 AMERICAN DEPOSITARY RECEIPT 

evidencing 
 AMERICAN DEPOSITARY SHARES 

representing 
 ORDINARY BEARER SHARES 

of 
 EVOTEC SE 

(Incorporated under the laws of the Federal Republic of Germany and the European Union) 

JPMORGAN CHASE BANK, N.A., a national banking association organized under the laws of the United States of America, as depositary hereunder (the
“Depositary”), hereby certifies that
                                         
        is the registered owner (a “Holder”) of
                                     American Depositary
Shares (“ADSs”), each (subject to paragraph (13) (Changes Affecting Deposited Securities)) representing one-half (1/2) of one ordinary bearer share (including the rights to receive
Shares 

  
 A-1 

 

 
  

 
described in paragraph (1) (Issuance of ADSs), “Shares” and, together with any other securities, cash or property from time to time held by the Depositary in respect or in
lieu of deposited Shares, the “Deposited Securities”), of EVOTEC SE, a corporation organized under the laws of the Federal Republic of Germany and the European Union (the “Company”), deposited under the Amended and
Restated Deposit Agreement, dated as of                      , 2021 (as amended from time to time, the “Deposit
Agreement”), among the Company, the Depositary and all Holders and Beneficial Owners from time to time of American Depositary Receipts issued thereunder (“ADRs”), each of whom by accepting an ADR becomes a party thereto.
The Deposit Agreement and this ADR (which includes the provisions set forth on the reverse hereof) shall be governed by and construed in accordance with the internal laws of the State of New York without giving effect to the application of the
conflict of law principles thereof. All capitalized terms used herein, and not defined herein, shall have the meanings ascribed to such terms in the Deposit Agreement. 

(1)  Issuance of ADSs. 

(a)  Issuance. This ADR is one of the ADRs issued under the Deposit Agreement. Subject to the other provisions hereof, the Depositary
may so issue ADRs for delivery at the Transfer Office (as hereinafter defined) only against deposit of: (i) Shares in a form satisfactory to the Custodian; or (ii) rights to receive Shares from the Company or any registrar, transfer agent,
clearing agent or other entity recording Share ownership or transactions. Shares or evidence of rights to receive Shares may be deposited through (x) electronic transfer of such Shares to the account maintained by the Custodian for such purpose
at the CSB, (y) evidence satisfactory to the Custodian of irrevocable instructions to cause such Shares to be transferred to such account or (z) delivery of the certificates representing such Shares. If use of the CSB book-entry system in
connection with the ADSs is discontinued at any time for any reason, the Company shall make such other book-entry arrangements as may be reasonably requested by the Depositary. At the request, risk and expense of the person depositing Shares, the
Depositary may accept deposits for forwarding to the Custodian and may deliver ADRs at a place other than its office. 

(b)  Lending. In its capacity as Depositary, the Depositary shall not lend Shares or ADSs. 

(c)  Representations and Warranties of Depositors. Every person depositing Shares under the Deposit Agreement represents and warrants
that: 
  

	 	(i)	 such Shares and the certificates therefor are duly authorized, validly issued and outstanding, fully paid, nonassessable
and legally obtained by such person, 

  

	 	(ii)	 all pre-emptive and comparable rights, if any, with respect to such Shares have
been validly waived or exercised, 

  
 A-2 

 

 
  

	 	(iii)	 the person making such deposit is duly authorized so to do, 

 

	 	(iv)	 the Shares presented for deposit are free and clear of any lien, encumbrance, security interest, charge, mortgage or
adverse claim and 

  

	 	(v)	 such Shares (A) are not “restricted securities” as such term is defined in Rule 144 under the Securities
Act of 1933 (“Restricted Securities”) unless at the time of deposit the requirements of paragraphs (c), (e), (f) and (h) of Rule 144 shall not apply and such Shares may be freely transferred and may otherwise be offered and
sold freely in the United States or (B) have been registered under the Securities Act of 1933. To the extent the person depositing Shares is an “affiliate” of the Company as such term is defined in Rule 144, the person also represents
and warrants that upon the sale of the ADSs, all of the provisions of Rule 144 that enable the Shares to be freely sold (in the form of ADSs) will be fully complied with and, as a result thereof, all of the ADSs issued in respect of such Shares will
not be on the sale thereof, Restricted Securities. 

 Such representations and warranties shall survive the deposit and withdrawal
of Shares and the issuance and cancellation of ADSs in respect thereof and the transfer of such ADSs. 
 (d)  The Depositary may refuse to
accept for such deposit any Shares identified by the Company in order to facilitate compliance with the requirements of the securities laws, rules and regulations of the United States, including, without limitation, the Securities Act of 1933 and
the rules and regulations made thereunder. 
 (2)  Withdrawal of Deposited Securities. Subject to paragraphs (4) (Certain
Limitations to Registration, Transfer etc.) and (5) (Liability of Holder or Beneficial Owner for Taxes, Duties and Other Charges), upon surrender of (a) a certificated ADR in a form satisfactory to the Depositary at the Transfer
Office or (b) proper instructions and documentation in the case of a Direct Registration ADR, in either case accompanied by such instruments of transfer as the Depositary may reasonably require, the Holder hereof is entitled to delivery
(i) to an account designated by such Holder with the CSB or an institution that maintains accounts with the CSB, of the Shares and other Deposited Securities that are eligible for deposit with the CSB and (ii) at the office of the
Custodian, of any Deposited Securities that are not eligible for deposit with the CSB, in each case at the time, underlying this ADR. At the request, risk and expense of the Holder hereof, the Depositary may deliver such Deposited Securities at such
other place as may have been requested by the Holder. Notwithstanding any other provision of the Deposit Agreement or this ADR, the 

  
 A-3 

 

 
  

 
withdrawal of Deposited Securities may be restricted only for the reasons set forth in General Instruction I.A.(1) of Form F-6 (as such instructions may be
amended from time to time) under the Securities Act of 1933. 
 (3)  Transfers, Split-Ups and
Combinations of ADRs. The Depositary or its agent will keep, at a designated transfer office (the “Transfer Office”), (a) a register (the “ADR Register”) for the registration, registration of transfer,
combination and split-up of ADRs, and, in the case of Direct Registration ADRs, shall include the Direct Registration System, which at all reasonable times will be open for inspection by Holders and the
Company for the purpose of communicating with Holders in the interest of the business of the Company or a matter relating to the Deposit Agreement and (b) facilities for the delivery and receipt of ADRs. The term ADR Register includes the
Direct Registration System. Title to this ADR (and to the Deposited Securities represented by the ADSs evidenced hereby), when properly endorsed (in the case of ADRs in certificated form) or upon delivery to the Depositary of proper instruments of
transfer, is transferable by delivery with the same effect as in the case of negotiable instruments under the laws of the State of New York; provided that the Depositary, notwithstanding any notice to the contrary, may treat the person in
whose name this ADR is registered on the ADR Register as the absolute owner hereof for all purposes and neither the Depositary nor the Company will have any obligation or be subject to any liability under the Deposit Agreement or any ADR to any
Beneficial Owner, unless such Beneficial Owner is the Holder hereof. Subject to paragraphs (4) and (5), this ADR is transferable on the ADR Register and may be split into other ADRs or combined with other ADRs into one ADR, evidencing the
aggregate number of ADSs surrendered for split-up or combination, by the Holder hereof or by duly authorized attorney upon surrender of this ADR at the Transfer Office properly endorsed (in the case of ADRs in
certificated form) or upon delivery to the Depositary of proper instruments of transfer and duly stamped as may be required by applicable law; provided that the Depositary may close the ADR Register at any time or from time to time when
deemed expedient by it or, in the case of the issuance book portion of the ADR Register, when reasonably requested by the Company solely in order to enable the Company to comply with applicable law; provided further, that the
Depositary shall have no liability and shall be indemnified by the Company in such event. At the request of a Holder, the Depositary shall, for the purpose of substituting a certificated ADR with a Direct Registration ADR, or vice versa, execute and
deliver a certificated ADR or a Direct Registration ADR, as the case may be, for any authorized number of ADSs requested, evidencing the same aggregate number of ADSs as those evidenced by the certificated ADR or Direct Registration ADR, as the case
may be, substituted. 
 (4)  Certain Limitations to Registration, Transfer, etc. Prior to the issue, registration, registration of
transfer, split-up or combination of any ADR, the delivery of any distribution in respect thereof, or, subject to the last sentence of paragraph (2) (Withdrawal of Deposited Securities), the withdrawal
of any Deposited Securities, and from time to time in the case of clause (b)(ii) of this paragraph (4), the Company, the Depositary or the Custodian may require: 

  
 A-4 

 

 
  

 (a)  payment with respect thereto of (i) any stock transfer or other tax or other
governmental charge, (ii) any stock transfer or registration fees in effect for the registration of transfers of Shares or other Deposited Securities upon any applicable register and (iii) any applicable charges as provided in paragraph
(7) (Charges of Depositary) of this ADR; 
 (b)  the production of proof satisfactory to it of (i) the identity of any
signatory and genuineness of any signature and (ii) such other information, including without limitation, information as to citizenship, residence, exchange control approval, beneficial or other ownership of, or interest in, any securities,
compliance with applicable law, regulations, provisions of or governing Deposited Securities and terms of the Deposit Agreement and this ADR, as it may deem necessary or proper; and 

(c)  compliance with such regulations as the Depositary may establish consistent with the Deposit Agreement. 

The issuance of ADRs, the acceptance of deposits of Shares, the registration, registration of transfer, split-up
or combination of ADRs or, subject to the last sentence of paragraph (2) (Withdrawal of Deposited Securities), the withdrawal of Deposited Securities may be suspended, generally or in particular instances, when the ADR Register or any
register for Deposited Securities is closed or when any such action is deemed advisable by the Depositary. 
 (5)  Liability of Holder or
Beneficial Owner for Taxes, Duties and Other Charges. 
 (a)      Liability for Taxes. If any
tax or other governmental charges (including any penalties and/or interest) shall become payable by or on behalf of the Custodian or the Depositary with respect to this ADR, any Deposited Securities represented by the ADSs evidenced hereby or any
distribution thereon, such tax or other governmental charge shall be paid by the Holder hereof to the Depositary and by holding or owning, or having held or owned, this ADR or any ADSs evidenced hereby, the Holder and all Beneficial Owners hereof
and thereof, and all prior Holders and Beneficial Owners hereof and thereof, jointly and severally, agree to indemnify, defend and save harmless each of the Depositary, the Company and their respective agents in respect of such tax or other
governmental charge. Neither the Depositary nor the Company, nor any of their respective agents, shall be liable to Holders or Beneficial Owners of the ADSs and ADRs for failure of any of them to comply with applicable tax laws, rules and/or
regulations. Notwithstanding the Depositary’s right to seek payment from current and former Beneficial Owners, by holding or owning, or having held or owned, an ADR, the Holder hereof (and prior Holder hereof) acknowledges and agrees that the
Depositary has no obligation to seek payment of amounts owing under this paragraph (5) from any current or former Beneficial Owner. 

  
 A-5 

 

 
  

 
The Depositary may refuse to effect any registration, registration of transfer, split-up or combination hereof or, subject to the last sentence of
paragraph (2) (Withdrawal of Deposited Securities), any withdrawal of such Deposited Securities until such payment is made. The Depositary may also deduct from any distributions on or in respect of Deposited Securities, or may sell by public
or private sale for the account of the Holder hereof any part or all of such Deposited Securities, and may apply such deduction or the proceeds of any such sale in payment of such tax or other governmental charge, the Holder hereof remaining liable
for any deficiency, and shall reduce the number of ADSs evidenced hereby to reflect any such sales of Shares. In connection with any distribution to Holders, the Company will remit to the appropriate governmental authority or agency all amounts (if
any) required to be withheld and owing to such authority or agency by the Company; and the Depositary and the Custodian will remit to the appropriate governmental authority or agency all amounts (if any) required to be withheld and owing to such
authority or agency by the Depositary or the Custodian. If the Depositary determines that any distribution in property other than cash (including Shares or rights) on Deposited Securities is subject to any tax that the Depositary or the Custodian is
obligated to withhold, the Depositary may dispose of all or a portion of such property in such amounts and in such manner as the Depositary deems necessary and practicable to pay such taxes, by public or private sale, and the Depositary shall
distribute the net proceeds of any such sale or the balance of any such property after deduction of such taxes to the Holders entitled thereto. 

(b)      Indemnifications Related to Taxes. Each Holder and Beneficial Owner agrees to indemnify the Depositary,
the Company, the Custodian and any of their respective officers, directors, employees, agents and affiliates against, and hold each of them harmless from, any claims by any governmental authority with respect to taxes, additions to tax, penalties or
interest arising out of any refund of taxes, reduced rate of withholding at source or other tax benefit obtained which obligations shall survive any transfer or surrender of ADSs or the termination of the Deposit Agreement. 

(6)  Disclosure of Interests. 

(a)  General. Each Holder of an ADR and all persons holding ADRs or beneficial interests in ADRs agree to comply with all applicable
provisions of German law and the Company’s Articles of Association regarding the notification of such person’s interest in Shares, which provisions at the date of the Deposit Agreement include Sections 33 and 34 of the Securities Trading
Act (Wertpapierhandelsgesetz). At the date of the Deposit Agreement, (i) the statutory notification obligations of the Securities Trading Act apply to anyone whose holding, either directly or by way of imputation pursuant to the provisions of
Section 33 et seqq. of the Securities Trading Act, of voting rights in the Company reaches or exceeds 3%, 5%, 10%, 15%, 20%, 25%, 

  
 A-6 

 

 
  

 
30%, 50% or 75% or, after having reached or exceeded any such threshold, falls below that threshold. Each beneficial owner of ADSs acknowledges that failure to provide on a timely basis any
required notification of an interest in Shares may result in withholding of certain rights, including voting and dividend rights, in respect of the Shares in which such beneficial owner of ADSs has an interest. In connection therewith, the Company
reserves the right to instruct Holders to deliver their ADSs for cancellation and withdrawal of the Deposited Securities so as to permit the Company to deal directly with the Holder thereof as a holder of Shares and Holders agree to comply with such
instructions. The Depositary agrees to cooperate with the Company in its efforts to inform Holders of the Company’s exercise of its rights under this paragraph and agrees to consult with, and provide reasonable assistance without risk,
liability or expense on the part of the Depositary, to the Company on the manner or manners in which it may enforce such rights with respect to any Holder. 

(b)  Jurisdiction Specific. 
 Any
summary of the laws and regulations of the Federal Republic of Germany and/or the European Union and/or of the terms of the Company’s constituent documents has been provided by the Company solely for the convenience of Holders, Beneficial
Owners and the Depositary. While such summaries are believed by the Company to be accurate as of the date of the Deposit Agreement, they are (i) summaries and as such may not include all aspects of the materials summarized as applicable to a
Holder or Beneficial Owner, and (ii) provided by the Company as of the date of the Deposit Agreement. The Holder or Beneficial Owner acknowledges that these laws and regulations and the Company’s constituent documents may change after the
date of the Deposit Agreement. Neither the Depositary nor the Company has any obligation to update any such summaries. 
 (7)  Charges of
Depositary. 
 (a)  Rights of the Depositary. The Depositary may charge, and collect from, (i) each person to whom ADSs are
issued, including, without limitation, issuances against deposits of Shares, issuances in respect of Share Distributions, Rights and Other Distributions (as such terms are defined in paragraph (10) (Distributions on Deposited
Securities)), issuances pursuant to a stock dividend or stock split declared by the Company, or issuances pursuant to a merger, exchange of securities or any other transaction or event affecting the ADSs or the Deposited Securities,
and (ii) each person surrendering ADSs for withdrawal of Deposited Securities or whose ADSs are cancelled or reduced for any other reason, U.S.$5.00 for each 100 ADSs (or portion thereof) issued, delivered, reduced, cancelled or
surrendered, or upon which a Share Distribution or elective distribution is made or offered (as the case may be). The Depositary may sell (by public or private sale) sufficient securities and property received in respect of Share Distributions,
Rights and Other Distributions prior to such deposit to pay such charge. 

  
 A-7 

 

 
  

 (b)  Additional charges by the Depositary. The following additional charges shall
also be incurred by the Holders, the Beneficial Owners, by any party depositing or withdrawing Shares or by any party surrendering ADSs and/or to whom ADSs are issued (including, without limitation, issuances pursuant to a stock dividend or stock
split declared by the Company or an exchange of stock regarding the ADSs or the Deposited Securities or a distribution of ADSs pursuant to paragraph (10) (Distributions on Deposited Securities)), whichever is applicable: 

 

	 	(i)	 a fee of U.S.$0.05 or less per ADS held for any Cash distribution made, or for any elective cash/stock dividend offered,
pursuant to the Deposit Agreement, 

  

	 	(ii)	 a fee for the distribution or sale of securities pursuant to paragraph (10) hereof, such fee being in an amount
equal to the fee for the execution and delivery of ADSs referred to above which would have been charged as a result of the deposit of such securities (for purposes of this paragraph (7) treating all such securities as if they were Shares) but
which securities or the net cash proceeds from the sale thereof are instead distributed by the Depositary to Holders entitled thereto,  

  

	 	(iii)	 an aggregate fee of U.S.$0.05 or less per ADS per calendar year (or portion thereof) for services performed by the
Depositary in administering the ADRs (which fee may be charged on a periodic basis during each calendar year and shall be assessed against Holders as of the record date or record dates set by the Depositary during each calendar year and shall be
payable at the sole discretion of the Depositary by billing such Holders or by deducting such charge from one or more cash dividends or other cash distributions), and 

 

	 	(iv)	 a fee for the reimbursement of such fees, charges and expenses as are incurred by the Depositary and/or any of its agents
(including, without limitation, the Custodian and expenses incurred on behalf of Holders in connection with compliance with foreign exchange control regulations or any law or regulation relating to foreign investment) in connection with the
servicing of the Shares or other Deposited Securities, the sale of securities (including, without limitation, Deposited Securities), the delivery of Deposited Securities or otherwise in connection with the Depositary’s or its Custodian’s
compliance with applicable law, rule or regulation (which fees and charges shall be assessed on a proportionate basis against Holders as of the record date or dates set by the Depositary and shall be payable at the sole discretion of the Depositary
by billing such Holders or by deducting such 

  
 A-8 

 

 
  

	 	 
charge from one or more cash dividends or other cash distributions). 

(c)  Other Obligations and Charges. The Company will pay all other charges and expenses of the Depositary and any agent of the
Depositary (except the Custodian) pursuant to agreements from time to time between the Company and the Depositary, except: 
  

	 	(i)	 stock transfer or other taxes and other governmental charges (which are payable by Holders or persons depositing Shares);

  

	 	(ii)	 SWIFT, cable, telex and facsimile transmission and delivery charges incurred at the request of persons depositing, or
Holders delivering Shares, ADRs or Deposited Securities (which are payable by such persons or Holders); and 

  

	 	(iii)	 transfer or registration fees for the registration or transfer of Deposited Securities on any applicable register in
connection with the deposit or withdrawal of Deposited Securities (which are payable by persons depositing Shares or Holders withdrawing Deposited Securities). 

(d)  Foreign Exchange Related Matters. To facilitate the administration of various depositary receipt transactions, including
disbursement of dividends or other cash distributions and other corporate actions, the Depositary may engage the foreign exchange desk within JPMorgan Chase Bank, N.A. (the “Bank”) and/or its affiliates in order to enter into spot
foreign exchange transactions to convert foreign currency into U.S. dollars (“FX Transactions”). For certain currencies, FX Transactions are entered into with the Bank or an affiliate, as the case may be, acting in a principal
capacity. For other currencies, FX Transactions are routed directly to and managed by an unaffiliated local custodian (or other third-party local liquidity provider), and neither the Bank nor any of its affiliates is a party to such FX Transactions.

 The foreign exchange rate applied to an FX Transaction will be either (i) a published benchmark rate, or (ii) a rate determined by a
third-party local liquidity provider, in each case plus or minus a spread, as applicable. The Depositary will disclose which foreign exchange rate and spread, if any, apply to such currency on the “Disclosures” page (or successor page) of
www.adr.com (as updated by the Depositary from time to time, “ADR.com”). Such applicable foreign exchange rate and spread may (and neither
the Depositary, the Bank nor any of their affiliates is under any obligation to ensure that such rate does not) differ from rates and spreads at which comparable transactions are entered into with other customers or the range of foreign exchange
rates and spreads at which the Bank or any of its affiliates enters into foreign exchange transactions in the relevant currency pair on the date of the FX 

  
 A-9 

 

 
  

 
Transaction. Additionally, the timing of execution of an FX Transaction varies according to local market dynamics, which may include regulatory requirements, market hours and liquidity in the
foreign exchange market or other factors. Furthermore, the Bank and its affiliates may manage the associated risks of their position in the market in a manner they deem appropriate without regard to the impact of such activities on the Company, the
Depositary, Holders or Beneficial Owners. The spread applied does not reflect any gains or losses that may be earned or incurred by the Bank and its affiliates as a result of risk management or other hedging related activity. 

Notwithstanding the foregoing, to the extent the Company provides U.S. dollars to the Depositary, neither the Bank nor any of its affiliates will
execute an FX Transaction as set forth herein. In such case, the Depositary will distribute the U.S. dollars received from the Company. 
 Further
details relating to the applicable foreign exchange rate, the applicable spread and the execution of FX Transactions will be provided by the Depositary on ADR.com. The Company, Holders and Beneficial Owners each acknowledge and agree that the terms
applicable to FX Transactions disclosed from time to time on ADR.com will apply to any FX Transaction executed pursuant to the Deposit Agreement. 

(e)  The right of the Depositary to receive payment of fees, charges and expenses as provided above shall survive the termination of the
Deposit Agreement. As to any Depositary, upon the resignation or removal of such Depositary, such right shall extend for those fees, charges and expenses incurred prior to the effectiveness of such resignation or removal. 

(f)  Disclosure of Potential Depositary Payments. The Depositary anticipates reimbursing the Company for certain expenses incurred by
the Company that are related to the establishment and maintenance of the ADR program upon such terms and conditions as the Company and the Depositary may agree from time to time. The Depositary may make available to the Company a set amount or a
portion of the Depositary fees charged in respect of the ADR program or otherwise upon such terms and conditions as the Company and the Depositary may agree from time to time. 

(8)  Available Information. The Deposit Agreement, the provisions of or governing Deposited Securities and any written communications
from the Company, which are both received by the Custodian or its nominee as a holder of Deposited Securities and made generally available to the holders of Deposited Securities, are available for inspection by Holders at the offices of the
Depositary and the Custodian, at the Transfer Office, on the website of the United States Securities and Exchange Commission (the “Commission”), or upon request from the Depositary (which request may be refused by the Depositary at
its discretion). The Depositary will distribute 

  
 A-10 

 

 
  

 
copies of such communications (or English translations or summaries thereof) to Holders when furnished by the Company. The Company is subject to the periodic reporting requirements of the
Securities Exchange Act of 1934 and accordingly files certain reports with the Commission. Such reports and other information can be inspected and retrieved by Holders and Beneficial Owners through the Commission’s EDGAR system on the
Commission’s Internet Web site located at the date of this Deposit Agreement at www.sec.gov and can be inspected and copied at public reference facilities maintained by the Commission located at the date of this Deposit Agreement at 100 F
Street, NE, Washington, DC 20549. The Company represents and warrants that as of the date of the Deposit Agreement, it is in compliance with the registration, reporting and other requirements of the Securities Exchange Act of 1934 and hereby
covenants and agrees to publish and file all reports, and to take all other actions, necessary and/or required to remain in compliance with the registration, reporting and other requirements of the Securities Exchange Act of 1934 as and when
required at all times hereafter in order to remain in compliance with such registration, reporting and other requirements. Each Holder and Beneficial Owner of an ADR and/or an interest therein by so holding or owning an ADR and/or an interest
therein, acknowledges and agrees that the Depositary does not assume any duty or responsibility to determine if the Company is in compliance with the current registration, reporting and other requirements of the Securities Exchange Act of 1934 or to
take any action if the Company is not complying with those requirements, and (ii) the Depositary is relying solely on the representations, warranties, covenants and agreements of the Company in Section 13(a) of the Deposit Agreement and
this paragraph (8) (Available Information) in connection therewith and may, and is expressly authorized by the Company and each Holder and Beneficial Owner of an ADR and/or an interest therein to, so rely on, and represent, warrant and
certify that the Company is compliant with the registration, reporting and other requirements of the Securities Exchange Act of 1934 based on such representations, warranties, covenants and agreements of the Company. 

(9)  Execution. This ADR shall not be valid for any purpose unless executed by the Depositary by the manual or facsimile signature of a
duly authorized officer of the Depositary. 
 Dated: 
  

			
	JPMORGAN CHASE BANK, N.A., as Depositary
		
	By	 	
                      
   

	Authorized Officer

 The Depositary’s office is located at 383 Madison Avenue, Floor 11, New York, New York 10179. 

  
 A-11 

 

 
  

 [FORM OF REVERSE OF ADR] 

(10)  Distributions on Deposited Securities. Subject to paragraphs (4) (Certain Limitations to Registration, Transfer etc.) and
(5) (Liability of Holder or Beneficial Owner for Taxes, Duties and other Charges), to the extent practicable, the Depositary will distribute to each Holder entitled thereto on the record date set by the Depositary therefor at such
Holder’s address shown on the ADR Register, in proportion to the number of Deposited Securities (on which the following distributions on Deposited Securities are received by the Custodian) represented by ADSs evidenced by such Holder’s
ADRs: 
 (a)  Cash. Any U.S. dollars available to the Depositary resulting from a cash dividend or other cash distribution or the
net proceeds of sales of any other distribution or portion thereof authorized in this paragraph (10) (“Cash”), on an averaged or other practicable basis, subject to (i) appropriate adjustments for taxes withheld, (ii) such
distribution being impermissible or impracticable with respect to certain Holders, and (iii) deduction of the Depositary’s and/or its agents’ fees and expenses in (1) converting any foreign currency to U.S. dollars by sale or in
such other manner as the Depositary may determine to the extent that it determines that such conversion may be made on a reasonable basis, (2) transferring foreign currency or U.S. dollars to the United States by such means as the Depositary
may determine to the extent that it determines that such transfer may be made on a reasonable basis, (3) obtaining any approval or license of any governmental authority required for such conversion or transfer, which is obtainable at a
reasonable cost and within a reasonable time and (4) making any sale by public or private means in any commercially reasonable manner. 

(b)  Shares. (i) Additional ADRs evidencing whole ADSs representing any Shares available to the Depositary resulting from a
dividend or free distribution on Deposited Securities consisting of Shares (a “Share Distribution”) and (ii) U.S. dollars available to it resulting from the net proceeds of sales of Shares received in a Share Distribution,
which Shares would give rise to fractional ADSs if additional ADRs were issued therefor, as in the case of Cash. 
 (c)  Rights.
(i) Warrants or other instruments in the discretion of the Depositary representing rights to acquire additional ADRs in respect of any rights to subscribe for additional Shares or rights of any nature available to the Depositary as a result of
a distribution on Deposited Securities (“Rights”), to the extent that the Company timely furnishes to the Depositary evidence satisfactory to the Depositary that the Depositary may lawfully distribute the same (the Company has no
obligation to so furnish such evidence), or (ii) to the extent the Company does not so furnish such evidence and sales of Rights are practicable, any U.S. dollars available to the Depositary from the net proceeds of sales of Rights as in the
case of Cash, or (iii) to the extent the Company does not so furnish such evidence and such sales cannot practicably be accomplished by reason of the nontransferability of the Rights, limited 

  
 A-12 

 

 
  

 
markets therefor, their short duration or otherwise, nothing (and any Rights may lapse). 

(d)  Other Distributions. (i) Securities or property available to the Depositary resulting from any distribution on Deposited
Securities other than Cash, Share Distributions and Rights (“Other Distributions”), by any means that the Depositary may deem equitable and practicable, or (ii) to the extent the Depositary deems distribution of such securities
or property not to be equitable and practicable, any U.S. dollars available to the Depositary from the net proceeds of sales of Other Distributions as in the case of Cash. 

The Depositary reserves the right to utilize a division, branch or affiliate of JPMorgan Chase Bank, N.A. to direct, manage and/or execute any public
and/or private sale of securities hereunder. Such division, branch and/or affiliate may charge the Depositary a fee in connection with such sales, which fee is considered an expense of the Depositary contemplated above and/or under paragraph (7)
(Charges of Depositary). Any U.S. dollars available will be distributed by checks drawn on a bank in the United States for whole dollars and cents. Fractional cents will be withheld without liability and dealt with by the Depositary in
accordance with its then current practices. All purchases and sales of securities will be handled by the Depositary in accordance with its then current policies, which are currently set forth on the “Disclosures” page (or successor page)
of ADR.com, the location and contents of which the Depositary shall be solely responsible for. 
 (11)  Record Dates. The Depositary
may, after consultation with the Company if practicable, fix a record date (which, to the extent applicable, shall be as near as practicable to any corresponding record date set by the Company) for the determination of the Holders who shall be
responsible for the fee assessed by the Depositary for administration of the ADR program and for any expenses provided for in paragraph (7) hereof as well as for the determination of the Holders who shall be entitled to receive any distribution
on or in respect of Deposited Securities, to give instructions for the exercise of any voting rights, to receive any notice or to act in respect of other matters and only such Holders shall be so entitled or obligated. 

(12)  Voting of Deposited Securities. 

(a)  Notice of any Meeting or Solicitation. As soon as practicable after receipt of notice of any meeting at which the holders of
Shares are entitled to vote, or of solicitation of consents or proxies from holders of Shares or other Deposited Securities, the Depositary shall fix the ADS record date in accordance with paragraph (11) above provided that if the Depositary
receives a written request from the Company in a timely manner and at least 30 days or such shorter time as the parties may agree, prior to the date of such vote or meeting, the Depositary shall, at the Company’s expense, distribute to Holders
a notice (the “Voting Notice”) stating (i) final information particular to such vote and meeting and any solicitation materials, 

  
 A-13 

 

 
  

 
(ii) that each Holder on the record date set by the Depositary will, subject to any applicable provisions of the laws of the Federal Republic of Germany and the European Union, be entitled to
instruct the Depositary as to the exercise of the voting rights, if any, pertaining to the Deposited Securities represented by the ADSs evidenced by such Holder’s ADRs and (iii) the manner in which such instructions may be given, including
instructions to give a discretionary proxy to a person designated by the Company. Each Holder shall be solely responsible for the forwarding of Voting Notices to the Beneficial Owners of ADSs registered in such Holder’s name. There is no
guarantee that Holders and Beneficial Owners generally or any Holder or Beneficial Owner in particular will receive the notice described above with sufficient time to enable such Holder or Beneficial Owner to return any voting instructions to the
Depositary in a timely manner. 
 (b)      Voting of Deposited Securities. Following actual receipt by the ADR
department responsible for proxies and voting of Holders’ instructions (including, without limitation, instructions of any entity or entities acting on behalf of the nominee for DTC), the Depositary shall, in the manner and on or before the
time established by the Depositary for such purpose, endeavor to vote or cause to be voted the Deposited Securities represented by the ADSs evidenced by such Holders’ ADRs in accordance with such instructions insofar as practicable and
permitted under the provisions of or governing Deposited Securities. The Depositary will not itself exercise any voting discretion in respect of any Deposited Securities. 

(c)      Alternative Methods of Distributing Materials. Notwithstanding anything contained in the Deposit
Agreement or any ADR, the Depositary may, to the extent not prohibited by any law, rule or regulation or by the rules, regulations or requirements of the stock exchange on which the ADSs are listed, in lieu of distribution of the materials provided
to the Depositary in connection with any meeting of or solicitation of consents or proxies from holders of Deposited Securities, distribute to the Holders a notice that provides Holders with or otherwise publicizes to Holders instructions on how to
retrieve such materials or receive such materials upon request (i.e., by reference to a website containing the materials for retrieval or a contact for requesting copies of the materials). Holders are strongly encouraged to forward their
voting instructions as soon as possible. Voting instructions will not be deemed received until such time as the ADR department responsible for proxies and voting has received such instructions, notwithstanding that such instructions may have been
physically received by JPMorgan Chase Bank, N.A., as Depositary, prior to such time. 
 (13)  Changes Affecting Deposited Securities.

 (a)      Subject to paragraphs (4) (Certain Limitations to Registration, Transfer etc.) and (5) (Liability
of Holder or Beneficial Owner for Taxes, Duties and Other Charges), the Depositary may, in its discretion, and shall if reasonably requested by the Company, amend this ADR or distribute additional or amended ADRs

  
 A-14 

 

 
  

 
(with or without calling this ADR for exchange) or cash, securities or property on the record date set by the Depositary therefor to reflect any change in par value, split-up, consolidation, cancellation or other reclassification of Deposited Securities, any Share Distribution or Other Distribution not distributed to Holders or any cash, securities or property available to the
Depositary in respect of Deposited Securities from (and the Depositary is hereby authorized to surrender any Deposited Securities to any person and, irrespective of whether such Deposited Securities are surrendered or otherwise cancelled by
operation of law, rule, regulation or otherwise, to sell by public or private sale any property received in connection with) any recapitalization, reorganization, merger, consolidation, liquidation, receivership, bankruptcy or sale of all or
substantially all the assets of the Company. 
 (b)      To the extent the Depositary does not so amend this ADR or
make a distribution to Holders to reflect any of the foregoing, or the net proceeds thereof, whatever cash, securities or property results from any of the foregoing shall constitute Deposited Securities and each ADS evidenced by this ADR shall
automatically represent its pro rata interest in the Deposited Securities as then constituted. 
 (c)      Promptly
upon the occurrence of any of the aforementioned changes affecting Deposited Securities, the Company shall notify the Depositary in writing of such occurrence and as soon as practicable after receipt of such notice from the Company, may instruct the
Depositary to give notice thereof, at the Company’s expense, to Holders in accordance with the provisions hereof. Upon receipt of such instruction, the Depositary shall give notice to the Holders in accordance with the terms thereof, as soon as
reasonably practicable. 
 (14)  Exoneration. 

(a)      The Depositary, the Company, and each of their respective directors, officers, employees, agents and affiliates
and each of them shall: (i) incur or assume no liability (including, without limitation, to Holders or Beneficial Owners) (A) if any present or future law, rule, regulation, fiat, order or decree of the Federal Republic of Germany, the
European Union, the United States or any other country or jurisdiction, or of any governmental or regulatory authority or any securities exchange or market or automated quotation system, the provisions of or governing any Deposited Securities, any
present or future provision of the Company’s charter, any act of God, war, terrorism, epidemic, pandemic, nationalization, expropriation, currency restrictions, work stoppage, strike, civil unrest, revolutions, rebellions, explosions, cyber,
ransomware or malware attack, computer failure or circumstance beyond its direct and immediate control shall prevent or delay, or shall cause any of them to be subject to any civil or criminal penalty in connection with, any act which the Deposit
Agreement or this ADR provides shall be done or performed by it or them (including, without limitation, voting pursuant to paragraph (12) hereof), or (B) by reason of any non-performance or delay,
caused as aforesaid, in the performance of 

  
 A-15 

 

 
  

 
any act or things which by the terms of the Deposit Agreement it is provided shall or may be done or performed or any exercise or failure to exercise any discretion given it in the Deposit
Agreement or this ADR (including, without limitation, any failure to determine that any distribution or action may be lawful or reasonably practicable); (ii) incur or assume no liability (including, without limitation, to Holders or Beneficial
Owners) except to perform its obligations to the extent they are specifically set forth in this ADR and the Deposit Agreement without gross negligence or willful misconduct and the Depositary shall not be a fiduciary or have any fiduciary duty to
Holders or Beneficial Owners; (iii) in the case of the Depositary and its agents, be under no obligation to appear in, prosecute or defend any action, suit or other proceeding in respect of any Deposited Securities, the ADSs or this ADR;
(iv) in the case of the Company and its agents hereunder be under no obligation to appear in, prosecute or defend any action, suit or other proceeding in respect of any Deposited Securities, the ADSs or this ADR, which in its opinion may
involve it in expense or liability, unless indemnity satisfactory to it against all expense (including fees and disbursements of counsel) and liability be furnished as often as may be required; and (v) not be liable (including, without
limitation, to Holders or Beneficial Owners) for any action or inaction by it in reliance upon the advice of or information from any legal counsel, any accountant, any person presenting Shares for deposit, any Holder, or any other person believed by
it to be competent to give such advice or information and/or, in the case of the Depositary only, the Company. The Depositary shall not be liable for the acts or omissions made by, or the insolvency of, any securities depository, clearing agency or
settlement system. 
 (b)      The Depositary. The Depositary shall not be responsible for, and shall incur no
liability in connection with or arising from, the insolvency of any Custodian that is not a branch or affiliate of JPMorgan Chase Bank, N.A. The Depositary shall not have any liability for the price received in connection with any sale of
securities, the timing thereof or any delay in action or omission to act nor shall it be responsible for any error or delay in action, omission to act, default or negligence on the part of the party so retained in connection with any such sale or
proposed sale. Notwithstanding anything to the contrary contained in the Deposit Agreement (including the ADRs) and, subject to the further limitations set forth in clause (o) of this paragraph (14), the Depositary shall not be responsible for,
and shall incur no liability in connection with or arising from, any act or omission to act on the part of the Custodian except to the extent that any Holder has incurred liability directly as a result of the Custodian having (i) committed
fraud or willful misconduct in the provision of custodial services to the Depositary or (ii) failed to use reasonable care in the provision of custodial services to the Depositary as determined in accordance with the standards prevailing in the
jurisdiction in which the Custodian is located. 
 (c)      The Depositary, its agents and the Company may rely and
shall be protected in acting upon any written notice, request, direction, instruction or document believed by them to be genuine and to have been signed, presented or 

  
 A-16 

 

 
  

 
given by the proper party or parties. 
 (d)     The Depositary shall
be under no obligation to inform Holders or Beneficial Owners about the requirements of the laws, rules or regulations or any changes therein or thereto of the Federal Republic of Germany, the European Union, the United States or any other country
or jurisdiction or of any governmental or regulatory authority or any securities exchange or market or automated quotation system. 

(e)     The Depositary and its agents will not be responsible for any failure to carry out any instructions to vote any of the
Deposited Securities, for the manner in which any voting instructions are given, including instructions to give a discretionary proxy to a person designated by the Company, for the manner in which any vote is cast, including, without limitation, any
vote cast by a person to whom the Depositary is instructed to grant a discretionary proxy pursuant to paragraph (12) hereof, or for the effect of any such vote. 

(f)      The Depositary may rely upon instructions from the Company or its counsel in respect of any approval or license
required for any currency conversion, transfer or distribution. 
 (g)     The Depositary and its agents may own and deal in
any class of securities of the Company and its affiliates and in ADRs. 
 (h)     Notwithstanding anything to the contrary
set forth in the Deposit Agreement or an ADR, the Depositary and its agents may fully respond to any and all demands or requests for information maintained by or on its behalf in connection with the Deposit Agreement, any Holder or Holders, any ADR
or ADRs or otherwise related hereto or thereto to the extent such information is requested or required by or pursuant to any lawful authority, including without limitation laws, rules, regulations, administrative or judicial process, banking,
securities or other regulators. 
 (i)      None of the Depositary, the Custodian or the Company, or any of their
respective directors, officers, employees, agents or affiliates shall be liable for the failure by any Holder or Beneficial Owner to obtain the benefits of credits or refunds of non-U.S. tax paid against such
Holder’s or Beneficial Owner’s income tax liability. 
 (j)      The Depositary is under no obligation to
provide the Holders and Beneficial Owners, or any of them, with any information about the tax status of the Company. None of the Depositary, the Custodian or the Company, or any of their respective directors, officers, employees, agents and
affiliates, shall incur any liability for any tax or tax consequences that may be incurred by Holders or Beneficial Owners on account of their ownership or disposition of the ADRs or ADSs. 

  
 A-17 

 

 
  

 (k)      The Depositary shall not incur any liability for the content of
any information submitted to it by or on behalf of the Company for distribution to the Holders or for any inaccuracy of any translation thereof, for any investment risk associated with acquiring an interest in the Deposited Securities, for the
validity or worth of the Deposited Securities, for the credit-worthiness of any third party, for allowing any rights to lapse upon the terms of the Deposit Agreement or for the failure or timeliness of any notice from the Company. 

(l)       Notwithstanding anything herein or in the Deposit Agreement to the contrary, the Depositary and the
Custodian(s) may use third-party delivery services and providers of information regarding matters such as, but not limited to, pricing, proxy voting, corporate actions, class action litigation and other services in connection herewith and the
Deposit Agreement, and use local agents to provide services such as, but not limited to, attendance at any meetings of security holders of issuers. Although the Depositary and the Custodian will use reasonable care (and cause their agents to use
reasonable care) in the selection and retention of such third-party providers and local agents, they will not be responsible for any errors or omissions made by them in providing the relevant information or services. 

(m)     The Depositary shall not be liable for any acts or omissions made by a successor depositary whether in connection with
a previous act or omission of the Depositary or in connection with any matter arising wholly after the removal or resignation of the Depositary. 

(n)      The Company has agreed to indemnify the Depositary and its agents under certain circumstances and the Depositary
has agreed to indemnify the Company under certain circumstances. 
 (o)      Notwithstanding any other provision of the
Deposit Agreement or this ADR to the contrary, neither the Depositary nor any of its agents shall be liable for any indirect, special, punitive or consequential damages (including, without limitation, legal fees and expenses) or lost profits, in
each case of any form incurred by any person or entity (including, without limitation, Holders and Beneficial Owners of ADRs and ADSs), whether or not foreseeable and regardless of the type of action in which such a claim may be brought. 

(p)      No provision of the Deposit Agreement or this ADR is intended to constitute a waiver or limitation of any rights
which Holders or Beneficial Owners may have under the Securities Act of 1933 or the Securities Exchange Act of 1934, to the extent applicable. 

(15)  Resignation and Removal of Depositary; the Custodian. 

(a)      Resignation. The Depositary may resign as Depositary by written notice of its election to do so delivered
to the Company, such resignation to take 

  
 A-18 

 

 
  

 
effect upon the appointment of a successor depositary and its acceptance of such appointment as provided in the Deposit Agreement. 

(b)      Removal. The Depositary may at any time be removed by the Company by no less than 60 days’ prior
written notice of such removal, to become effective upon the later of (i) the 60th day after delivery of the notice to the Depositary and (ii) the appointment of a successor depositary and its acceptance of such appointment as provided in
the Deposit Agreement. 
 (c)      The Custodian. The Depositary may appoint substitute or additional Custodians
and the term “Custodian” refers to each Custodian or all Custodians as the context requires. 
 (16)  Amendment.
Subject to the last sentence of paragraph (2) (Withdrawal of Deposited Securities), the ADRs and the Deposit Agreement may be amended by the Company and the Depositary, provided that any amendment that imposes or increases any fees or
charges (other than stock transfer or other taxes and other governmental charges, transfer or registration fees, SWIFT, cable, telex or facsimile transmission costs, delivery costs or other such expenses), or that shall otherwise prejudice any
substantial existing right of Holders or Beneficial Owners, shall become effective 30 days after notice of such amendment shall have been given to the Holders. Every Holder and Beneficial Owner at the time any amendment to the Deposit Agreement so
becomes effective shall be deemed, by continuing to hold such ADR, to consent and agree to such amendment and to be bound by the Deposit Agreement as amended thereby. In no event shall any amendment impair the right of the Holder of any ADR to
surrender such ADR and receive the Deposited Securities represented thereby, except in order to comply with mandatory provisions of applicable law. Any amendments or supplements that (i) are reasonably necessary (as agreed by the Company and the
Depositary) in order for (a) the ADSs to be registered on Form F-6 under the Securities Act of 1933 or (b) the ADSs or Shares to be traded solely in electronic book-entry form and (ii) do not in
either such case impose or increase any fees or charges to be borne by Holders, shall be deemed not to prejudice any substantial rights of Holders or Beneficial Owners. Notwithstanding the foregoing, if any governmental body or regulatory body
should adopt new laws, rules or regulations which would require amendment or supplement of the Deposit Agreement or the form of ADR to ensure compliance therewith, the Company and the Depositary may amend or supplement the Deposit Agreement and the
ADR at any time in accordance with such changed laws, rules or regulations. Such amendment or supplement to the Deposit Agreement in such circumstances may become effective before a notice of such amendment or supplement is given to Holders or
within any other period of time as required for compliance. Notice of any amendment to the Deposit Agreement or form of ADRs shall not need to describe in detail the specific amendments effectuated thereby, and failure to describe the specific
amendments in any such notice shall not render such notice invalid, provided, however, that, in each such case, the notice given to the Holders identifies a means for Holders and 

  
 A-19 

 

 
  

 
Beneficial Owners to retrieve or receive the text of such amendment (i.e., upon retrieval from the Commission’s, the Depositary’s or the Company’s website or upon request
from the Depositary). 
 (17)  Termination. The Depositary may, and shall at the written direction of the Company, terminate the
Deposit Agreement and this ADR by mailing notice of such termination to the Holders at least 30 days prior to the date fixed in such notice for such termination; provided, however, if the Depositary shall have (i) resigned as Depositary
hereunder, notice of such termination by the Depositary shall not be provided to Holders unless a successor depositary shall not be operating hereunder within 60 days of the date of such resignation, or (ii) been removed as Depositary
hereunder, notice of such termination by the Depositary shall not be provided to Holders unless a successor depositary shall not be operating hereunder on the 60th day after the Company’s
notice of removal was first provided to the Depositary. Notwithstanding anything to the contrary herein, the Depositary may terminate the Deposit Agreement without notice to the Company, but subject to giving 30 days’ notice to the Holders,
under the following circumstances: (i) in the event of the Company’s bankruptcy or insolvency, (ii) if the Shares cease to be listed on an internationally recognized stock exchange, (iii) if the Company effects (or will effect) a
redemption of all or substantially all of the Deposited Securities, or a cash or share distribution representing a return of all or substantially all of the value of the Deposited Securities, or (iv) there occurs a merger, consolidation, sale
of assets or other transaction as a result of which securities or other property are delivered in exchange for or in lieu of Deposited Securities. 

After the date so fixed for termination, the Depositary and its agents will perform no further acts under the Deposit Agreement and this ADR, except to
receive and hold (or sell) distributions on Deposited Securities and deliver Deposited Securities being withdrawn. As soon as practicable after the date so fixed for termination, the Depositary shall use its reasonable efforts to sell the Deposited
Securities and shall thereafter (as long as it may lawfully do so) hold in an account (which may be a segregated or unsegregated account) the net proceeds of such sales, together with any other cash then held by it under the Deposit Agreement,
without liability for interest, in trust for the pro rata benefit of the Holders of ADRs not theretofore surrendered. After making such sale, the Depositary shall be discharged from all obligations in respect of the Deposit Agreement
and this ADR, except to account for such net proceeds and other cash. After the date so fixed for termination, the Company shall be discharged from all obligations under the Deposit Agreement except for its obligations to the Depositary and its
agents. 
 (18)  Appointment; Acknowledgements and Agreements. Each Holder and each Beneficial Owner, upon acceptance of any ADSs or
ADRs (or any interest in any of them) issued in accordance with the terms and conditions of the Deposit Agreement shall be deemed for all purposes to (a) be a party to and bound by the terms of the Deposit Agreement and the applicable ADR(s),
(b) appoint the Depositary 

  
 A-20 

 

 
  

 
its attorney-in-fact, with full power to delegate, to act on its behalf and to take any and all actions
contemplated in the Deposit Agreement and the applicable ADR(s), to adopt any and all procedures necessary to comply with applicable law and to take such action as the Depositary in its sole discretion may deem necessary or appropriate to carry out
the purposes of the Deposit Agreement and the applicable ADR(s), the taking of such actions to be the conclusive determinant of the necessity and appropriateness thereof, and (c) acknowledge and agree that (i) nothing in the Deposit
Agreement or any ADR shall give rise to a partnership or joint venture among the parties thereto, nor establish a fiduciary or similar relationship among such parties, (ii) the Depositary, its divisions, branches and affiliates, and their
respective agents, may from time to time be in the possession of non-public information about the Company, Holders, Beneficial Owners and/or their respective affiliates, (iii) the Depositary and its
divisions, branches and affiliates may at any time have multiple banking relationships with the Company, Holders, Beneficial Owners and/or the affiliates of any of them, (iv) the Depositary and its divisions, branches and affiliates may, from
time to time, be engaged in transactions in which parties adverse to the Company or the Holders or Beneficial Owners and/or their respective affiliates may have interests, (v) nothing contained in the Deposit Agreement or any ADR(s) shall
(A) preclude the Depositary or any of its divisions, branches or affiliates from engaging in any such transactions or establishing or maintaining any such relationships, or (B) obligate the Depositary or any of its divisions, branches or
affiliates to disclose any such transactions or relationships or to account for any profit made or payment received in any such transactions or relationships, (vi) the Depositary shall not be deemed to have knowledge of any information held by
any branch, division or affiliate of the Depositary and (vii) notice to a Holder shall be deemed, for all purposes of the Deposit Agreement and this ADR, to constitute notice to any and all Beneficial Owners of the ADSs evidenced by such
Holder’s ADRs. For all purposes under the Deposit Agreement and this ADR, the Holder hereof shall be deemed to have all requisite authority to act on behalf of any and all Beneficial Owners of the ADSs evidenced by this ADR. 

(19)  Waiver. EACH PARTY TO THE DEPOSIT AGREEMENT (INCLUDING, FOR AVOIDANCE OF DOUBT, EACH HOLDER AND BENEFICIAL OWNER OF, AND/OR
HOLDER OF INTERESTS IN, ADSS OR ADRS) HEREBY IRREVOCABLY WAIVES, TO THE FULLEST EXTENT PERMITTED BY APPLICABLE LAW, ANY RIGHT IT MAY HAVE TO A TRIAL BY JURY IN ANY SUIT, ACTION OR PROCEEDING AGAINST THE DEPOSITARY AND/OR THE COMPANY DIRECTLY OR
INDIRECTLY ARISING OUT OF, BASED ON OR RELATING IN ANY WAY TO THE SHARES OR OTHER DEPOSITED SECURITIES, THE ADSs OR THE ADRs, THE DEPOSIT AGREEMENT OR ANY TRANSACTION CONTEMPLATED HEREIN OR THEREIN, OR THE BREACH HEREOF OR THEREOF (WHETHER BASED ON
CONTRACT, TORT, COMMON LAW OR ANY OTHER THEORY), INCLUDING, WITHOUT LIMITATION, ANY SUIT, ACTION, CLAIM OR PROCEEDING UNDER THE UNITED STATES FEDERAL SECURITIES LAWS. No provision of the Deposit Agreement or this ADR is intended to constitute a
waiver or limitation of any rights which a Holder or any Beneficial Owner may have under the Securities Act of 1933 or the Securities Exchange Act of 1934, to the extent 

  
 A-21 

 

 
  

 
applicable. 
 (20)  Jurisdiction. By holding or owning an ADR or ADS or
an interest therein, Holders and Beneficial Owners each irrevocably agree that any legal suit, action or proceeding against or involving Holders or Beneficial Owners brought by the Company or the Depositary, arising out of or based upon the Deposit
Agreement, the ADSs, the ADRs or the transactions contemplated therein, herein, thereby or hereby, may be instituted in a federal or state court in New York, New York, and by holding or owning an ADR or ADS or an interest therein each irrevocably
waives any objection that it may now or hereafter have to the laying of venue of any such proceeding, and irrevocably submits to the non-exclusive jurisdiction of such courts in any such suit, action or
proceeding. By holding or owning an ADR or ADS or an interest therein, Holders and Beneficial Owners each also irrevocably agree that any legal suit, action or proceeding against or involving the Depositary brought by Holders or Beneficial Owners,
arising out of or based upon the Deposit Agreement, the ADSs, the ADRs or the transactions contemplated therein, herein, thereby or hereby, including, without limitation, claims under the Securities Act of 1933, may be instituted only in the United
States District Court for the Southern District of New York (or in the state courts of New York County in New York if either (i) the United States District Court for the Southern District of New York lacks subject matter jurisdiction over a
particular dispute or (ii) the designation of the United States District Court for the Southern District of New York as the exclusive forum for any particular dispute is, or becomes, invalid, illegal or unenforceable). 

(21)  Elective Distributions in Cash or Shares. Whenever the Company intends to distribute a dividend payable at the election of the
holders of Shares in cash or in additional Shares, the Company shall give notice thereof to the Depositary at least 30 days prior to the proposed distribution stating whether or not it wishes such elective distribution to be made available to
Holders. Upon receipt of notice indicating that the Company wishes such elective distribution to be made available to Holders, the Depositary shall consult with the Company to determine, and the Company shall assist the Depositary in its
determination, whether it is lawful and reasonably practicable to make such elective distribution available to the Holders. The Depositary shall make such elective distribution available to Holders only if (i) the Company shall have timely
requested that the elective distribution is available to Holders, (ii) the Depositary shall have determined that such distribution is reasonably practicable and (iii) the Depositary shall have received satisfactory documentation within the
terms of Section 14 of the Deposit Agreement including, without limitation, any legal opinions of counsel in any applicable jurisdiction that the Depositary in its reasonable discretion may request, at the expense of the Company. If the above
conditions are not satisfied, the Depositary shall, to the extent permitted by law, distribute to the Holders, on the basis of the same determination as is made in the local market in respect of the Shares for which no election is made, either
(x) cash or (y) additional ADSs representing such additional Shares. If the above conditions are satisfied, the Depositary shall establish a record date and establish procedures to enable Holders to

  
 A-22 

 

 
  

 
elect the receipt of the proposed dividend in cash or in additional ADSs. The Company shall assist the Depositary in establishing such procedures to the extent necessary. Nothing herein shall
obligate the Depositary to make available to Holders a method to receive the elective dividend in Shares (rather than ADSs). There can be no assurance that Holders or Beneficial Owners generally, or any Holder and/or Beneficial Owner in particular,
will be given the opportunity to receive elective distributions on the same terms and conditions as the holders of Shares. 

  
 A-23EX-4.4

Table of Contents

 Exhibit 4.4 

THE SYMBOL “[***]” DENOTES PLACES WHERE CERTAIN IDENTIFIED 

INFORMATION HAS BEEN EXCLUDED FROM THE EXHIBIT BECAUSE IT IS BOTH (i)

NOT MATERIAL, AND (ii) WOULD LIKELY CAUSE COMPETITIVE HARM TO THE 

COMPANY IF PUBLICLY DISCLOSED 
  

 
 INVESTMENT AGREEMENT 

 
  

AMONG 

EVOTEC SE 

AND 
 ATIC
SECOND INTERNATIONAL INVESTMENT COMPANY LLC 

12 OCTOBER 2020 

Table of Contents

 CONTENTS 

 

							
			
	Clause	 	 	  	Page	 
			
	1.	 	ISSUE AND SUBSCRIPTION OF NEW SHARES	  	 	2	 
			
	2.	 	DELIVERY AND PAYMENT	  	 	3	 
			
	3.	 	CONDITIONS TO SUBSCRIPTION AND PAYMENT	  	 	3	 
			
	4.	 	TERMINATION	  	 	3	 
			
	5.	 	ATTENDANCE RATE AT 2021 SHAREHOLDERS’ MEETING	  	 	4	 
			
	6.	 	REPRESENTATIONS OF THE COMPANY	  	 	5	 
			
	7.	 	REPRESENTATIONS OF THE INVESTOR	  	 	6	 
			
	8.	 	UNDERTAKINGS OF THE COMPANY	  	 	7	 
			
	9.	 	NOTICES	  	 	7	 
			
	10.	 	COSTS	  	 	8	 
			
	11.	 	CONFIDENTIALITY	  	 	8	 
			
	12.	 	GENERAL PROVISIONS	  	 	8	 
			
	13.	 	GOVERNING LAW; PLACE OF JURISDICTION	  	 	9	 

  

					
	 SCHEDULE 1
	  	 	    	 
		
	 FORM OF SUBSCRIPTION CERTIFICATE
	  			
		
	 SCHEDULE 2
	  			
		
	 FORM OF OFFICERS’ CERTIFICATE
	  			
		
	 SCHEDULE 3
	  			
		
	 TEXT OF PUBLIC ANNOUNCEMENTS
	  			

  
 i 

Table of Contents

 INVESTMENT AGREEMENT 

between 
  

	(1)	 EVOTEC SE, a European stock corporation (Europäische Aktiengesellschaft,
SE) established under the laws of the Federal Republic of Germany and registered in the commercial register (Handelsregister) of the Local Court (Amtsgericht) of Hamburg (the Commercial Register) under HRB 156381 (the
Company); and 

  

	(2)	 ATIC SECOND INTERNATIONAL INVESTMENT COMPANY LLC, a limited liability company established under the laws
of the United Arab Emirates and registered with the commercial register of the United Arab Emirates under number CN-1191915 (the Investor); 

(the Company and the Investor hereinafter collectively being referred to as the Parties and each of them a Party). 

PREAMBLE 
  

	(A)	 The Company is a drug discovery alliance and development partnership company focused on rapidly progressing
innovative product approaches with leading pharmaceutical and biotechnology companies, academics, patient advocacy groups and venture capitalists. 

  

	(B)	 As of 31 December 2019, the Company’s share capital (Grundkapital) amounted to EUR
150,902,578.00 and was divided into 150,902,578 ordinary bearer shares with no par value (auf den Inhaber lautde Stammaktien ohne Nennbetrag) (the Existing Shares). 

 

	(C)	 By resolutions of the Company’s annual shareholders’ meeting held on 14 June 2017 and
20 June 2018, the management board (Vorstand) of the Company (the Management Board) has been authorised, until 13 June 2022, to increase, with the consent of the supervisory board (Aufsichtsrat) of the Company (the
Supervisory Board), the Company’s share capital by up to EUR 29,332,457,00 (the Authorised Capital) by issuing up to 29,332,457 new ordinary bearer shares with no par value (auf den Inhaber lautende Stammaktien ohne
Nennbetrag) (the Authorisation). Pursuant to § 5(5)(c) of the Company’s articles of association, the Management Board is furthermore authorized to exclude, with the consent of the Supervisory Board, the statutory subscription
rights (Bezugsrechte), insofar as (i) the new shares are issued against cash contributions (Kapitalerhöhung gegen Bareinlagen) and the proportional share of the share capital that applies to the shares to be newly issued does
not in the aggregate exceed the amount of a total of EUR 14,666,228.00 or, should this amount be lower, of a total of 10% of the share capital existing at the time of effectiveness and at the time of first exercise of this authorisation to exclude
subscription rights, and (ii) the issue price of the newly issued shares is not significantly lower than the market price of the Existing Shares with the same features at the time of the final determination of the issue price. This
authorisation has been registered with the Commercial Register on 29 March 2019. 

  

	(D)	 The Investor is indirectly wholly owned by Mubadala Investment Company PJSC (Mubadala). Mubadala is a
sovereign investor managing a global portfolio, aimed at generating sustainable financial returns for the Government of Abu Dhabi with a focus on inter alia health care, pharmaceuticals and medical technology. 

 

	(E)	 The Company wishes to raise additional capital and also to obtain a stable anchor investor in order to
accelerate its organic and inorganic growth strategy. The funds raised will be used to accelerate such organic and inorganic growth of the Company in line with its existing growth strategy which comprises various initiatives (e.g. opportunistic
M&A activities, extension of the Company’s manufacturing capacity, etc.). This will also be mirrored by the Company’s capital market communication. 

  
 1 

Table of Contents

	(F)	 Against this background, the Company intends to make partial use of the Authorised Capital and to issue
9,182,652 new ordinary bearer shares with no par value (auf den Inhaber lautende Stammaktien ohne Nennbetrag), each with full dividend entitlement as of the financial year beginning 1 January 2020 (each a New Share and together
the New Shares) to the Investor against cash contributions and the Investor intends to subscribe and pay for the New Shares as further set out in this Agreement (the Capital Increase). 

 

	(G)	 The Management Board has resolved on 12 October 2020 on the Capital Increase and the Supervisory Board has
approved such resolution on the same day. 

 NOW, THEREFORE, the Parties hereby agree as follows: 

 

	1.	 ISSUE AND SUBSCRIPTION OF NEW SHARES 

 

	1.1	 Subject to the terms and conditions set forth in this Agreement, the Company agrees to issue, and the Investor
agrees to subscribe for the New Shares at an issue price (Ausgabebetrag und Bezugspreis) of EUR 21.7802 per New Share (the Issue Price), meaning the Volume Weighted Average Price (VWAP) of the Company’s shares in Xetra trading on
the Frankfurt Stock Exchange on the last 5 (five) trading days prior to the date of the resolution of the Management Board less a discount of 2.5% (two point five). The aggregate Issue Price amounts to EUR 199,999,997.10 (mathematically
rounded) (the Aggregate Issue Price). The New Shares shall be ordinary bearer shares with no par value (auf den Inhaber lautende Stammaktien ohne Nennbetrag) and shall carry the same rights and obligations as the Existing Shares,
including dividend entitlement as of the financial year beginning 1 January 2020. 

  

	1.2	 Subject to the conditions set forth in this Agreement, the Investor shall by 19 October 2020 at the
latest deliver a subscription certificate (Zeichnungsschein) relating to the New Shares (the Subscription Certificate, a form of which is set forth in Schedule 1) duly signed in duplicate form pursuant to
§§ 203(1), 185(1) German Stock Corporation Act (Aktiengesetz, AktG) to the notary public [***] with the instruction to hold the Subscription Certificate in escrow until released in accordance with Clause 1.3 below. Further, subject
to the terms and conditions set forth in this Agreement, the Investor shall on or before 12:00 CET on 19 October 2020 or the day as agreed between the Parties pursuant to Clause 1.5 (such time referred to as Subscription
Certificate Release Time), effect payment of the Aggregate Issue Price to a special account of the Company with COMMERZBANK Aktiengesellschaft (the Bank) entitled “Evotec – Sonderkonto
Kapitalerhöhung” (the New Shares Capital Increase Account) and with the following account details: [***], with value as of the same day. Upon payment of the Aggregate Issue Price, the Bank shall issue and deliver
to the Company a certificate pursuant to §§ 203(1), 188(2), 36(2), 36a(1) and 37(1) AktG confirming credit of the Aggregate Issue Price to the New Shares Capital Increase Account (the Bank Certificate). 

 

	1.3	 Unless previously released by email notice of the Investor to the notary public [***] (cf. Clause 1.2), the
Subscription Certificate shall be deemed released by the Investor from escrow upon presentation by the Company to the notary public of the Bank Certificate. Without undue delay (unverzüglich) upon release of the
Subscription Certificate from escrow, the Company shall execute the necessary documentation for the registration of the consummation (Durchführung) of the Capital Increase and shall without undue delay
(unverzüglich) thereafter file such documentation with the Commercial Register. 

  

	1.4	 Without undue delay (unverzüglich) upon the registration of the Capital Increase with the
Commercial Register, the Company shall, per email with PDF attachment, furnish the Investor with a copy of an electronic excerpt of the Commercial Register evidencing the registration of the Capital Increase. 

  
 2 

Table of Contents

	1.5	 If the registration with the Commercial Register of the Capital Increase has not been effected by
3 November, 17:00 CET the Subscription Certificate for the New Shares shall, in accordance with its terms, expire and the Company shall without undue delay (unverzüglich) repay the Aggregate Issue Price to the Investor
to an account designated by the Investor. In such event, the Investor and the Company may agree that the Investor (i) effects new credits corresponding to the Aggregate Issue Price to the New Shares Capital Increase Account, (ii) submits a
new Subscription Certificate (the New Subscription Certificate) for the New Shares (to expire in accordance with its terms on a date to be determined jointly by the Company and the Investor), to be held in escrow by the notary public, [***],
until released. 

  

	2.	 DELIVERY AND PAYMENT 

Promptly on the day on which the Capital Increase is registered with the Commercial Register (the time of such registration referred to as the
Registration Time), the Company shall deliver a duly executed global certificate representing the New Shares (the Global Certificate) to Baader Bank AG, Weihenstephaner Strasse 4, 85716 Unterschleissheim, Germany (Baader Bank)
with the instruction to Baader Bank to deliver such Global Certificate to Clearstream Banking AG for inclusion in Clearstream Banking AG’s book-entry transfer system. The Company and the Investor shall furthermore issue appropriate delivery
free of payment instructions to effect credit of the New Shares to a deposit account designated by the Investor by credit through Clearstream Banking AG’s book-entry system. 

 

	3.	 CONDITIONS TO SUBSCRIPTION AND PAYMENT 

 

	3.1	 The obligations of the Investor to release the Subscription Certificate or the New Subscription Certificate, as
the case may be, from escrow and to effect payment of the Aggregate Issue Price are subject to the conditions precedent (aufschiebende Bedingungen) that 

 

	 	(a)	 the Investor shall have received copies of the resolution (i) of the Management Board to increase the
Company’s share capital under the Authorisation with exclusion of subscription rights and to issue the New Shares at the Aggregate Issue Price to the Investor and (ii) of the Supervisory Board approving the Management Board’s
resolution referred to in (i); and 

  

	 	(b)	 the Investor shall have received a certificate dated 19 October 2020 and signed by the chief executive
officer and the chief financial officer of the Company, in the form as attached in Schedule 2 hereto. 

  

	3.2	 The Investor may in its sole discretion and upon such terms as it thinks fit, waive in writing compliance with
the whole or any part of the conditions precedent set out in Clause 3.1. The conditions in Clause 3.1 shall be deemed to have been fulfilled as soon as the Aggregate Issue Price has been transferred to the New Shares Capital Increase Account.

  

	4.	 TERMINATION 

  

	4.1	 The Investor may terminate this agreement 

 

	 	(a)	 upon the non-occurrence of a condition precedent referred to in Clause
3.1 by the Subscription Certificate Release Time, unless the Investor has declared a waiver; or 

  

	 	(b)	 if any of the representations and warranties made by the Company in this Agreement shall be or become untrue or
incorrect before the Subscription Certificate Release Time; or 

  
 3 

Table of Contents

	 	(c)	 if before the Subscription Certificate Release Time, except as a result of the transactions contemplated by
this Agreement, the Company publishes a notice pursuant to Article 17(1) of Regulation (EU) No 596/2014 of the European Parliament and of the Council of 16 April 2014 on market abuse (the Market Abuse Regulation) about a fact or
development (i) which, as commercially reasonably determined by the Investor, has or is expected to result in a material adverse effect on the condition (financial or otherwise), or on the earnings, business affairs or prospects of the Company
and its subsidiaries taken as a whole, whether or not arising in the ordinary course of business, or (ii) which is reasonably likely to result in a material adverse effect on the Company’s ability to perform its obligations under this
Agreement. 

 Upon notice of such termination being given by the Investor, the Company shall without undue delay
(unverzüglich) repay the Aggregate Issue Price to the Investor to an account designated by the Investor and return to the Investor the Subscription Certificate or the New Subscription Certificate, as the case may be, and this Agreement
shall terminate and be of no further effect and no Party shall have any liability to any other Party in respect of this Agreement, except that any termination of this Agreement shall not affect the obligations of the Parties under Clause 11.

  

	4.2	 If any of the representations and warranties made by the Company in this Agreement shall be or become untrue or
incorrect after the Subscription Certificate Release Time and prior to the Registration Time, the Investor may request from the Company by written notification to employ its best efforts to procure a withdrawal of the application for registration of
the Capital Increase with the Commercial Register. If the application is withdrawn successfully, the Company shall without undue delay (unverzüglich) repay the Aggregate Issue Price to an account designated by the Investor and return to
the Investor the Subscription Certificate, and this Agreement shall terminate and be of no further effect and no party shall have any liability to any other in respect of this Agreement, except that any termination of this Agreement shall not affect
the obligations of the Parties under Clause 11. 

  

	5.	 ATTENDANCE RATE AT 2021 SHAREHOLDERS’ MEETING 

 

	5.1	 The Company shall use its best efforts to take, and the Investor confirms that it fully supports, measures
deemed appropriate by the Company to ensure that the attendance rate at the Company’s shareholders’ meeting in 2021 and subsequent shareholders’ meetings equals or exceeds the respective attendance rate at the shareholders’
meeting held on 16 June 2020 (without taking into account the Investor’s shareholding), in particular by engaging with its shareholders in advance of the shareholders’ meeting in order to encourage their attendance. Such
measures may include 

  

	 	(a)	 to select the locations of the Company’s shareholders’ meetings based on good accessibility (airport
or city centre, good public transportation) and attractiveness of the venue itself (e.g. Evotec’s head quarter; attractive hotels or event locations in the centre of Hamburg), among other things; 

 

	 	(b)	 to include in the invitations to the Company’s shareholders’ meetings a ticket for Hamburg’s
public transportation free-of-charge for the shareholders; 

  

	 	(c)	 to follow a detailed plan which enables the Company to inform the shareholders on time and within the legally
required timeframes throughout the processes prior to the Company’s shareholders’ meetings, which also allows the Company to closely monitor the status of registration in a timely manner. In case the Company becomes aware of the fact that
some major shareholders have not registered yet, the Company’s Legal or IR department is contacting them to remind them of the ongoing process or to offer assistance. 

  
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	5.2	 The Company’s Supervisory Board shall use its right to provide guidance (Vorschläge
zur Beschlussfassung) pursuant to § 124(3) first sentence AktG in such a way that a person to be proposed by the Investor shall be suggested for the election as a member of the Company’s Supervisory Board for a term of office that is
identical to the remaining term of office of all other members of the Supervisory Board and with the same rights and obligations as any other member, provided that such person meets the requirements of statutory law, the German Corporate Governance
Code and the approved competence profile of the Company’s Supervisory Board as of the date of such proposal. Should a seat on the Company’s supervisory board become vacant, the Company shall apply for an appointment of an eligible
representative of the Investor until the next Company’s shareholders’ meeting and use its best efforts to propose to the next Company’s shareholders’ meeting to elect such representative of the Investor pursuant to sentence 1 of
this Clause 5.2. 

  

	6.	 REPRESENTATIONS OF THE COMPANY 

The Company hereby represents to the Investor by way of independent promise of guarantee (selbständiges Garantieversprechen) pursuant to §
311(1) of the German Civil Code (Bürgerliches Gesetzbuch, BGB) that the statements set out in Clause 6.1 to Clause 6.12 below (each a Statement and together the Statements) are true and correct as of the date of this
Agreement (the Signing Date) and as of the Subscription Certificate Release Time. 
  

	6.1	 The Company is duly incorporated and validly existing under the laws of its jurisdiction of incorporation and
has the requisite corporate power and authority to carry on its business as currently conducted. 

  

	6.2	 No insolvency proceedings have been commenced in respect of the assets of the Company or any of its
subsidiaries and no circumstances exist which would require an application for the commencement of such proceedings under applicable insolvency regulations. 

  

	6.3	 Together with 994.915 shares which have been issued during the months January through September 2020 and
possibly shares which have been issued in October up until the Signing Date, both from the Company’s contingent capital in connection with an employee stock option program, the Existing Shares represent the entire share capital
(Grundkapital) of the Company and all contributions (Einlagen) required to be made in respect thereof have been made in full and have not been repaid. 

 

	6.4	 The Company has the corporate capacity to enter into, and perform its obligations under, this Agreement, which,
upon approval of the Supervisory Board as contemplated in Clause 3.1(a), will have been duly authorised by the Company. 

  

	6.5	 Upon execution, this Agreement constitutes legal, valid and binding obligations of the Company.

  

	6.6	 To the Company’s best knowledge, all consents, approvals, authorisations or other actions required to be
taken by the Company under applicable law and regulations for, the execution of this Agreement, the issuance of the New Shares by the Company and the performance by the Company of its obligations under this Agreement, have been unconditionally
obtained and are in full force and effect and no notice to, filing with or exemption or review by any domestic or foreign authorities, agencies, courts, commissions or other entities including stock exchanges and other self-regulatory organizations
(collectively Governmental Authorities) having jurisdiction over the Company is necessary for the consummation by the Company of the transactions contemplated by this Agreement, save that (i) the issuance of the New
Shares will require an application by the Company for registration of the consummation (Durchführung) of the Capital Increase with, and registration by, the Commercial Register, (ii) the admission and introduction of the New Shares
to trading will require applications to the Frankfurt Stock Exchange (Frankfurter Wertpapierbörse) by the Company as well as admission and 

  
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introduction decisions by the Frankfurt Stock Exchange (Frankfurter Wertpapierbörse), (iii) the Company will be obliged to file announcements to be published pursuant to Article
17(1) of the Market Abuse Regulation (the MAR) in connection with the transactions contemplated by this Agreement with the Bundesanstalt für Finanzdienstleistungsaufsicht (BaFin) and (iv) the Company will be obliged to file
announcements according to § 40 (upon receipt of a major holdings notification by the Investor), § 41 and f§ 49 German Securities Trading Act (Wertpapierhandelsgesetz, WpHG). 

 

	6.7	 As at the Signing Date, there is no lawsuit or, to the Company’s best knowledge, investigation or
proceeding pending or threatened against the Company before any court, arbitral body or governmental authority which in any manner challenges or seeks to prevent, alter or materially delay the transactions contemplated by this Agreement.

  

	6.8	 Since 1 January 2020, to the Company’s best knowledge, the Company has complied with all reporting
and voting rights notification requirements, including the requirement to publicly disclose inside information under stock exchange and other securities laws (including the MAR), and – except in connection with the transactions contemplated by
this Agreement – it does currently not make use of the possibility to delay the disclosure of inside information pursuant to Article 17(4) MAR. 

  

	6.9	 The New Shares will, upon registration in the Commercial Register, be validly issued shares of the Company,
fully paid up and freely transferable and will be free of any third party rights. The New Shares will, upon issuance, be fully fungible with each other and with the Existing Shares. 

 

	6.10	 Any subscription rights (Bezugsrechte) of any existing shareholders of the Company in connection with
the issuance of the New Shares are validly excluded and the New Shares will be free of subscription rights. 

  

	6.11	 The Company is a “foreign private issuer” within the meaning of Regulation S under the U.S.
Securities Act of 1933, as amended, and reasonably believes that there is no “substantial U.S. market interest” as defined in Regulation S under the U.S. Securities Act of 1933, as amended, in the New Shares or in securities that are of
the same class as the New Shares. 

  

	6.12	 Neither the Company nor – as far as the Company is aware of – any of its affiliates, nor any party
acting on behalf or for the account of any of them has, within a period of 15 Frankfurt Stock Exchange trading days prior to the Signing Date, engaged in any trading activities involving shares of the Company (including any derivative and hedging
transactions involving such shares) which might reasonably be expected to cause or result in stabilization or manipulation of the price of the Company’s share price. 

 

	7.	 REPRESENTATIONS OF THE INVESTOR 

The Investor hereby represents to the Company, by way of an independent promise of guarantee (selbständiges Garantieversprechen) pursuant to
§ 311(1) BGB, that the statements set out in Clause 7.1 to Clause 7.6 below are true and correct as of the Signing Date and as of the Subscription Certificate Release Time. 

 

	7.1	 The Investor is duly incorporated and validly existing under the laws of its jurisdiction of incorporation and
has the requisite corporate power and authority to carry on its business as currently conducted. 

  

	7.2	 No insolvency proceedings have been commenced in respect of the assets of the Investor and no circumstances
exist which would require an application for the commencement of such proceedings under applicable insolvency regulations. 

  
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	7.3	 The Investor has the corporate capacity to enter into, and perform its obligations under, this Agreement and
this Agreement has been duly authorised by the Investor. 

  

	7.4	 Upon execution, this Agreement will constitute legal, valid and binding obligations of the Investor,
enforceable against it in accordance with its terms. 

  

	7.5	 The Investor fully complied with all applicable anti-trust regulations including other regulatory requirements
under any relevant jurisdiction and has ensured that the consummation of the transaction in this Agreement will not be delayed or suspended, respectively, as a result of any competent authority refusing to unconditionally approve of and clear the
transaction. 

  

	7.6	 As at the Signing Date, there is no lawsuit or, to the Investor’s best knowledge, investigation or
proceeding pending or threatened against the Investor before any court, arbitral body or governmental authority which in any manner challenges or seeks to prevent, alter or materially delay the transactions contemplated by this Agreement.

  

	8.	 UNDERTAKINGS OF THE COMPANY 

 

	8.1	 The Company undertakes to publish, prior to the Subscription Certificate Release Time, a notice pursuant to
Article 17(1) MAR materially in the form attached hereto as Schedule 3. 

  

	8.2	 The Company undertakes not to cause any new shares in the Company to be admitted to trading on a regulated
market in reliance on Article 1(5) lit. a of Regulation (EU) No 1129/2017 of the European Parliament and of the Council of 14 June 2017 on the prospectus to be published when securities are offered to the public or admitted to trading on a
regulated market before the admission to trading of the New Shares has been completed. 

  

	8.3	 The Company shall use its best efforts to cause the New Shares to be admitted and introduced to trading
(Zulassung) on the regulated market (Regulierter Markt) segment of the Frankfurt Stock Exchange (Frankfurter Wertpapierbörse) and the sub-segment thereof with additional
post-admission obligations (Prime Standard) at the latest one day following registration of the Capital Increase with the Commercial Register. The Company confirms that it has authorised and mandated Baader Bank to file, together with the Company,
and to pursue the application for admission and introduction to trading of the New Shares to the regulated market (Regulierter Markt) segment of the Frankfurt Stock Exchange and the sub-segment thereof
with additional post-admission obligations (Prime Standard). 

  

	9.	 NOTICES 

  

	9.1	 All notices, communication and declarations of will which are given pursuant to, or in connection with, this
Agreement shall be given in writing in the English language and shall be transmitted by hand, by post, by email (with signed PDF attachment) or by telefax to the Parties as specified in more detail in Clause 9.2. 

 

	9.2	 All such notices, communication and declarations of will shall (subject to any changes notified in writing to
the other Parties) be transmitted to the Parties at the following addresses, and marked for the attention of the following persons: 

  

	 	(a)	 Company: 

Evotec SE 
 Essener Bogen
7 
 22419 Hamburg 
 Federal
Republic of Germany 
 Attention: Dr Werner Lanthaler with copy to Dr Christian Dargel 

[***] 

  
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	 	(b)	 Investor: 

ATIC Second International Investment Company LLC 

[***] 
 [***] 

 

	10.	 COSTS 

Each Party shall bear its own costs and expenses (including the fees, costs and expenses of its advisors) relating to the preparation, negotiation and
implementation of this Agreement and the transactions contemplated herein. For the avoidance of doubt, the Company agrees that it will pay or cause to be paid any fees, costs and expenses payable in connection with (i) the registration of the
Capital Increase and (ii) the admission and introduction of the New Shares to the regulated market (Regulierter Markt) segment of the Frankfurt Stock Exchange (Frankfurter Wertpapierbörse) and the sub-segment thereof with additional post-admission obligations (Prime Standard). 
  

	11.	 CONFIDENTIALITY 

The Parties agree to keep strictly confidential any and all information (written or oral), data (including, but not limited to any data of financial, technical
or otherwise business-related nature) or any other statement, regardless of its kind and content arising out of or in connection with this Agreement (together Confidential Information) including any information and
knowledge derived from the Confidential Information in accordance with the provisions of the Mutual Confidentiality Agreement entered into between the Company and the Investor on 3 August 2020. 

 

	12.	 GENERAL PROVISIONS 

 

	12.1	 Unless expressly provided otherwise in this Agreement, all amounts payable under or in connection with this
Agreement shall be paid in Euro free of costs and charges (kosten- und spesenfrei) in immediately available funds by wire transfer with value on the relevant due date (mit Wertstellung zum jeweiligen Fälligkeitstag).

  

	12.2	 No Party may pledge or assign any rights or claims under this Agreement in whole or in part without the prior
written consent of the other Party. 

  

	12.3	 This Agreement contains the entire agreement between the Parties with respect to the subject-matter hereof and
supersedes all prior agreements and understandings with respect thereto. 

  

	12.4	 Any amendment or supplementation (Ergänzung) of this Agreement must be in writing,
unless a stricter form (such as notarial recording) is required by mandatory law. This shall also apply to any waiver of the need to comply with the provisions of this Clause 12.4. 

 

	12.5	 The Schedules to this Agreement shall form an integral part of this Agreement. 

  
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	12.6	 Except as otherwise expressly provided for in this Agreement, this Agreement shall not grant any rights to
third parties and shall not constitute a contract for the benefit of third parties (Vertrag zu Gunsten Dritter) or a contract with protective effect for third parties (Vertrag mit Schutzwirkung für Dritte). 

 

	12.7	 If any provision of this Agreement is or becomes wholly or partially invalid, void or unenforceable, this shall
not affect the validity of the other provisions of this Agreement. The same shall apply if it should transpire that this Agreement contains a contractual omission (Lücke). Instead of the invalid, void or unenforceable provision, the
Parties shall agree on an arrangement which comes as close as legally possible to what the Parties were trying to achieve with the invalid, void or unenforceable provision (or, as the case may be, the invalid, void or unenforceable part thereof). In
the event that a contractual omission needs to be filled, an arrangement shall be agreed upon which, in accordance with the purpose and intent of this Agreement, comes as close as possible to what the Parties would have agreed upon if they had
thought about the matter at the time of conclusion of this Agreement. 

  

	13.	 GOVERNING LAW; PLACE OF JURISDICTION 

 

	13.1	 This Agreement and all non-contractual obligations arising out of or in
connection with this Agreement shall be governed by the laws of Germany without recourse to the German rules of private international law. Place of performance for the obligations hereto shall be Hamburg, Germany. 

 

	13.2	 All disputes arising in connection with this Agreement or its validity shall be finally settled in accordance
with the Arbitration Rules of the German Institution of Arbitration (Deutsche Institution für Schiedsgerichtsbarkeit (DIS) e.V.) without recourse to the ordinary courts of law. The place of arbitration is Hamburg, Germany. The number of
arbitrators is three. The language of the arbitral proceedings is English. The applicable substantive law is the law of the Federal Republic of Germany. 

[Signature page to follow] 

  
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 SIGNATORIES TO THE INVESTMENT AGREEMENT 

 

							
	Hamburg, 12 October 2020	 		 	

							
			
	Evotec SE	 		 	

							
				
	By:	 	   
	 	By:	 	   

	Name:	 		 	Name:	 	
	Title:	 		 	Title:	 	

 [Signature page to Investment Agreement] 

  
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	Abu Dhabi, 12 October 2020	 		 	
			
	ATIC Second International Investment Company LLC	 		 	

							
				
	By:	 	   
	 	By:	 	   

							
	Name:	 	 [***]
	 	Name:	 	 [***]

	Title:	 	Authorised Signatory	 	Title:	 	Authorised Signatory

 [Signature page to Investment Agreement] 

  
 11

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