Document:

EX-10.1

 Exhibit 10.1 

Tyme Technologies, Inc. 

Nonqualified Stock Option Agreement 

Tyme Technologies, Inc., a Delaware corporation (the “Company”), pursuant to the Company’s 2015 Equity Incentive Plan
(the “Plan”), has granted to ###PARTICIPANT_NAME### (the “Optionee”) a nonqualified stock option (the “Option”) to purchase a total of ###TOTAL_AWARDS### shares (each, a “Share”) of
the common stock, par value $0.0001 per share (the “Common Stock”), of the Company, at the exercise price of ###GRANT_PRICE### per Share (the “Exercise Price”), on the terms and conditions set forth in this
Nonqualified Stock Option Plan Agreement (this “Agreement”) and, in all respects, subject to the terms and conditions of the Plan. The date of grant of the Option is ###GRANT_DATE### (the “Date of Grant”). The
Option is not intended to qualify as an incentive stock option under Section 422 of the Code. Capitalized terms not otherwise defined in this Agreement shall have the meanings assigned to such terms in the Plan. 

1. Duration. Subject to the earlier termination as provided in this Agreement or under the Plan, the Option shall expire and shall no longer be
exercisable as of the close of business on ###EXPIRY_DATE### (the “Expiration Date”). 
  

	2.	 Anti Dilution Provisions. 

(a) If there is any stock dividend, stock split or combination of Shares or other change in capital structure of the Company described in
Section 4.4 of the Plan, the number and amount of Shares then subject to the Option and the Exercise Price shall be proportionately and appropriately adjusted as determined by the Committee, whose determination shall be final, conclusive and
binding upon Optionee and the Company. 
 (b) If there is any other change in the Common Stock, including a reorganization, sale or exchange
of assets, exchange of shares, offering of subscription rights, or a merger, consolidation or similar transaction in which the Company is the surviving corporation, an adjustment, if any, shall be made in the Shares then subject to the Option and
the Exercise Price as the Board or Committee may deem equitable, and whose determination shall be final, conclusive and binding upon Optionee and the Company. Failure of the Board or the Committee to provide for an adjustment pursuant to this
paragraph 2(b) prior to the effective date of any Company action referred to in this paragraph 2(b) shall be conclusive evidence that no adjustment is required in consequence of such action. 

(c) If the Company is merged into or consolidated with any other corporation and the Company is not the surviving corporation, or if the
Company sells all or substantially all of the Company’s assets to any other corporation, then either: 
 (i) the Company
shall cause provisions to be made for the continuance of the Option after such event or for the substitution for the Option of an option covering the number and class of securities which the Optionee would have been entitled to receive in such
merger, consolidation or if the Optionee had been the holder of record of a number of Shares equal to the number of Shares covered by the unexercised portion of the Option immediately prior to such merger, consolidation or sale; or 

 (ii) the Company shall give to Optionee written notice of the Company’s
election not to cause such provision to be made and the Option shall become exercisable in full (or, at the election of the Optionee, in part) at any time during a period of thirty days, to be designated by the Company, ending not more than ten days
prior to the effective date of the merger, consolidation or sale, in which case the Option shall not be exercisable to any extent after the expiration of such thirty -day period; provided, however, that this paragraph 2(c)(ii) shall not apply
in the case of a material transaction resulting from the Company’s strategic evaluation process announced on March 29, 2022. 

Notwithstanding the provisions of this paragraph 2(c), in no event shall the Option be exercisable after the Expiration Date. 

3. Non -Transferability. The Option shall not be transferable by Optionee, other than by (x) will, the laws of descent or
distribution or (y) pursuant to a proceeding under Title 11 of the U.S. Bankruptcy Code or similar insolvency proceeding, and is exercisable during the lifetime of Optionee only by Optionee, except as otherwise specifically provided in this
Agreement or the Plan. The terms of this Agreement shall be binding upon the executors, administrators, heirs, successors and assigns of Optionee. 
 4.
Certain Rights Not Conferred by Option. Optionee shall not, by virtue of holding the Option, be entitled to any rights of a stockholder in the Company. 

5. Expenses. The Company shall pay all original issue and transfer taxes with respect to the issuance of the Shares pursuant hereto and all other fees
and expenses necessarily incurred by the Company in connection therewith. 
  

	6.	 Exercise of Options. 

(a) Subject to paragraphs 6(b) and 6(i) of this Agreement, the Option shall become exercisable on the dates and in the amounts as follows: 

###VEST_SCHEDULE_TABLE### 
 Notwithstanding the
foregoing, unless otherwise determined by the Board, in the event of a material transaction resulting from the Company’s strategic evaluation process announced on March 29, 2022 while Optionee is in the employ or a consultant of the
Company, the Option, to the extent unvested and unexercisable, shall fully vest and become exercisable as of immediately prior to the closing of such transaction. 

(b) In the event of a Change of Control while Optionee is in the employ or a consultant of the Company, the Option, to the extent unvested and
unexercisable, shall fully vest and become exercisable as of immediately prior to such Change of Control. 
 (c) The Option shall be
exercisable, in whole or part and from time to time, but subject to the exercise schedule set forth in paragraph 6(a) of this Agreement, by written or electronic notice to the Chief Executive Officer or Secretary of the Company of such exercise,
complying with the Plan and applicable procedures established by the Committee or the Company. Such notice shall specify the number of Shares for which the Option is being exercised (which number, if less than all of the Shares then subject to
exercise, shall be 100 or an integral multiple thereof) and shall be accompanied by: 

  
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 (i) payment of the full exercise price for the Shares for which the Option
is being exercised; and 
 (ii) this Agreement. 

(d) The form of payment of the Exercise Price for Shares purchased pursuant to each exercise of the Option shall be paid in full at the time of
each purchase in one or a combination of the following methods: 
 (i) cash; 

(ii) check (subject to collection); 

(iii) in the discretion of the Committee, surrender to the Company of other Shares owned by the Optionee, which: 

(A) have a Fair Market Value on the date of surrender equal to the aggregate exercise price of the Shares as to which the
Option is being exercised; and 
 (B) have been owned of record by Optionee for at least six months; 

(iv) by “net exercise,” by means of exercising the Option, to the extent exercisable, and receiving such number of
Shares having a Fair Market Value on the date of such net exercise equal to the difference between: 
 (A) the Fair Market
Value of the full number of Shares issuable upon exercise of the Option on the date of such net exercise; and 
 (B) the
Exercise Price multiplied by the full number of Shares issuable upon exercise of the Option; or 
 (v) if there is a public
market for Shares, subject to applicable law, by: 
 (A) assignment to the Company of the net proceeds (to the extent
necessary to pay such exercise price) to be received from a registered broker upon the sale of the Shares or assignment of the net proceeds (to the extent necessary to pay such exercise price) of a loan from such broker in such amount; or 

(B) such other consideration and method of payment for the issuance of stock to the extent permitted under applicable law and
satisfying the requirements of Rule 16b -3 promulgated pursuant to the Exchange Act. 

  
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 (e) No Shares shall be delivered upon exercise of the Option until all laws, rules and
regulations which the Committee may, in its sole discretion, deem applicable have been complied with. If a registration statement under the Securities Act is not then in effect with respect to the Shares issuable upon such exercise, the Company may
require as a condition precedent that Optionee, upon exercising the Option, deliver to the Company a written representation and undertaking, satisfactory in form and substance to the Committee, that, among other things, Optionee is acquiring the
Shares for Optionee’s own account for investment purposes only and not with a view to the distribution thereof. 
 (f) Optionee shall
not be considered a record holder of the Shares so purchased for any purpose until the date on which Optionee is actually recorded as the holder of such Shares in the records of the Company. 

(g) Notwithstanding Section 5.7(a) of the Plan, if the Optionee is Terminated for any reason except death, Disability, or for Cause, then
the Optionee may exercise the Option (i) only to the extent that the Option would have been exercisable on the Termination Date (after taking into account any acceleration under this Agreement, the Plan and/or the Optionee’s employment
agreement), and (ii) no later than twenty-four months after the Termination Date (or such longer period not exceeding five years as may be determined by the Committee), but in any event, no later than the Expiration Date. 

(h) Subject to paragraphs 6(g) and 6(i) of this Agreement, in the event of Optionee’s death, disability or termination of employment, the
exercisability of the Option shall be governed by the provisions of Section 5.7 of the Plan, unless such provisions are waived by the Committee, in the Committee’s sole discretion. 

(i) Notwithstanding anything in this Agreement to the contrary and for the avoidance of doubt, to the extent that the Optionee has entered into
an employment agreement with the Company that provides for vesting and/or exercise terms that are more favorable than the vesting or exercise terms set forth in this Agreement or the Plan, such more favorable vesting and/or exercise terms shall
apply. 
 7. Withholding of Tax. To the extent that the exercise of the Option, or any event pursuant to this Agreement, results in the incurrence of
compensation or other taxable income by Optionee that is subject to withholding by the Company, Optionee must satisfy such tax withholding obligation by giving written notice to the Company, prior to the delivery of Shares, of the Optionee’s
election to either (a) deliver to the Company an amount of cash equal to the tax withholding amount required under applicable tax laws or regulations or (b) have the Company deduct from the number of Shares that would have otherwise been
delivered to Optionee a number of such Shares having a Fair Market Value equal to such tax withholding amount. Regardless of any action of the Company, Optionee acknowledges that Optionee is ultimately liable for such tax withholding obligation. The
Company shall not be required to deliver any Shares in respect of the Option under this Agreement until such liability is satisfied. 
 8. Continued
Employment or Consultancy. Nothing herein shall be deemed to create any employment or consultancy or guaranty of continued employment or consultancy or limit in any way the Company’s right to terminate Optionee’s employment or
consultancy at any time. 

  
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 9. Investment Representation and Legend of Certificates. Optionee acknowledges that, for any period
in which a registration statement with respect to the Option and/or Shares under the Securities Act of 1933, as amended (the “Securities Act”), is not effective, Optionee shall hold the Option and will purchase and/or own the Shares
for investment purposes only and not for resale or distribution. The Company shall have the right to place upon the face and/or reverse side of any stock certificate or certificates evidencing the Shares such legend as the Committee may prescribe
for the purpose of preventing disposition of such Shares in violation of the Securities Act. 
  

			
	Tyme Technologies, Inc.
		
	By:	 	 /s/ Richard Cunningham

		 	Richard Cunningham
		 	Chief Executive Officer

  
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 OPTIONEE ACKNOWLEDGEMENT 

OPTIONEE ACKNOWLEDGES AND AGREES THAT, EXCEPT AS SET FORTH IN THIS AGREEMENT OR OPTIONEE’S EMPLOYMENT OR CONSULTANCY AGREEMENT, THE
EXERCISABILITY OF THE SHARES SUBJECT TO THIS AGREEMENT AND THE OPTION IS EARNED ONLY BY CONTINUING EMPLOYMENT OR CONSULTANCY AT THE WILL OF THE COMPANY (NOT THROUGH THE ACT OF BEING HIRED, BEING GRANTED THE OPTION OR ACQUIRING SHARES HEREUNDER).
OPTIONEE FURTHER ACKNOWLEDGES AND CONFIRMS THAT NOTHING IN THIS AGREEMENT, NOR IN THE PLAN WHICH IS INCORPORATED HEREIN BY REFERENCE, SHALL CONFER UPON OPTIONEE ANY RIGHT WITH RESPECT TO CONTINUATION OF EMPLOYMENT OR CONSULTANCY BY THE COMPANY, NOR
SHALL IT INTERFERE IN ANY WAY WITH OPTIONEE’S OR THE COMPANY’S RIGHT, SUBJECT TO OPTIONEE’S AND THE COMPANY’S RIGHTS UNDER OTHER AGREEMENTS, IF ANY, WITH THE COMPANY, TO TERMINATE EMPLOYMENT OR CONSULTANCY AT ANY TIME, WITH OR
WITHOUT CAUSE. 
 Optionee acknowledges receipt of a copy of the Plan and certain information related to the Plan and the Company and
represents that Optionee is familiar with the terms and provisions of the Plan, and hereby accepts the Option subject to all of the terms and provisions of the Plan. Optionee has reviewed the Plan and this Agreement in their entirety, has had an
opportunity to obtain the advice of counsel prior to executing this Agreement and fully understands all of the terms and provisions of the Option and this Agreement. Optionee hereby agrees to accept as binding, conclusive and final all decisions or
interpretations of the Committee upon any questions arising under the Plan. Optionee further agrees to notify the Company upon any change in the residence address currently set forth in the Company’s records. 

Accepted and agreed as of 
 the date as first set forth
above: 
 Name: ###PARTICIPANT_NAME### 

  
 6EX-10.2

 Exhibit 10.2 

TYME TECHNOLOGIES, INC. 

INDEMNIFICATION AGREEMENT 

This Indemnification Agreement (“Agreement”), dated as of April [DATE], 2022, is by and between Tyme Technologies, Inc., a
Delaware corporation (the “Company”) and [NAME OF DIRECTOR/OFFICER] (the “Indemnitee”). 
 WHEREAS,
Indemnitee is [a director/an officer] of the Company; 
 WHEREAS, both the Company and Indemnitee recognize the increased risk of litigation
and other claims being asserted against directors and officers of public companies; 
 WHEREAS, the board of directors of the Company (the
“Board”) has determined that enhancing the ability of the Company to retain and attract as directors and officers the most capable persons is in the best interests of the Company and that the Company therefore should seek to assure
such persons that indemnification and insurance coverage is available; and 
 WHEREAS, in recognition of the need to provide Indemnitee with
substantial protection against personal liability, in order to procure Indemnitee’s continued service as a [director/officer] of the Company and to enhance Indemnitee’s ability to serve the Company in an effective manner, and in order to
provide such protection pursuant to express contract rights (intended to be enforceable irrespective of, among other things, any amendment to the Company’s certificate of incorporation or bylaws (collectively, the “Constituent
Documents”), any change in the composition of the Board or any change in control or business combination transaction relating to the Company), the Company wishes to provide in this Agreement for the indemnification of, and the advancement
of Expenses (as defined in Section 1(f) below) to, Indemnitee as set forth in this Agreement and for the continued coverage of Indemnitee under the Company’s directors’ and officers’ liability insurance policies. 

NOW, THEREFORE, in consideration of the foregoing and the Indemnitee’s continuing to provide services to the Company, the parties agree
as follows: 
 1. Definitions. For purposes of this Agreement, the following terms shall have the following meanings: 

(a) “Beneficial Owner” has the meaning given to the term “beneficial owner” in Rule 13d-3 under the Securities Exchange Act of 1934, as amended (the “Exchange Act”). 

(b) “Change in Control” means the occurrence after the date of this Agreement of any of the following events:

 (i) any Person is or becomes the Beneficial Owner, directly or indirectly, of securities of the Company representing 25%
or more of the Company’s then outstanding Voting Securities; 
 (ii) the consummation of a reorganization, merger or
consolidation, unless immediately following such reorganization, merger or consolidation, all of the Beneficial Owners of the Voting Securities of the Company immediately prior to such transaction beneficially own, directly or indirectly, more than
51% of the combined voting power of the outstanding Voting Securities of the entity resulting from such transaction; 

 (iii) during any period of two consecutive years, not including any period
prior to the execution of this Agreement, individuals who at the beginning of such period constituted the Board (including for this purpose any new directors whose election by the Board or nomination for election by the Company’s stockholders
was approved by a vote of at least two-thirds (2/3) of the directors then still in office who either were directors at the beginning of the period or whose election or nomination for election was previously so
approved) cease for any reason to constitute at least a majority of the Board; or 
 (iv) the stockholders of the Company
approve a plan of complete liquidation or dissolution of the Company or an agreement for the sale or disposition by the Company of all or substantially all of the Company’s assets. 

(c) “Claim” means: 

(i) any threatened, pending or completed action, suit, proceeding or alternative dispute resolution mechanism, whether civil,
criminal, administrative, arbitrative, investigative or other, and whether made pursuant to federal, state or other law; or 

(ii) any formal or informal inquiry, hearing or investigation that the Indemnitee reasonably determines in good faith might
lead to the institution of any such action, suit, proceeding or alternative dispute resolution mechanism. 
 (d)
“Delaware Court” shall have the meaning ascribed to it in Section 8(e) below. 
 (e)
“Disinterested Director” means a director of the Company who is not and was not a party to the Claim in respect of which indemnification is sought by Indemnitee. 

(f) “Expenses” means any and all expenses, including attorneys’ and experts’ fees, court costs,
transcript costs, travel expenses, duplicating, printing and binding costs, telecommunications charges, and all other costs and expenses incurred in connection with investigating, defending, being a witness in, being made (or asked) to respond to
discovery requests or other requests for information, or participating in (including on appeal), or preparing to defend, be a witness in, or make or respond to discovery requests or other requests for information, or participate in, any Claim.
Expenses also shall include (i) Expenses incurred in connection with any appeal resulting from any Claim, including without limitation the premium, security for, and other costs relating to any cost bond, supersedeas bond, or other appeal bond
or its equivalent, and (ii) for purposes of Section 4 only, Expenses incurred by Indemnitee in connection with the interpretation, enforcement or defense of Indemnitee’s rights under this Agreement, by litigation or otherwise.
Expenses, however, shall not include amounts paid in settlement by Indemnitee or the amount of judgments or fines against Indemnitee. The parties agree that, for purposes of any advancement of Expenses for which Indemnitee has made written demand to
the Company in accordance with this Agreement, all Expenses included in such demand that are certified by affidavit of Indemnitee’s counsel as being reasonable shall be presumed conclusively to be reasonable. 

(g) “Expense Advance” means any payment of Expenses advanced to Indemnitee by the Company pursuant to
Section 3 or Section 4 hereof. 

  
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 (h) “Indemnifiable Event” means any event or occurrence,
whether occurring before, on or after the date of this Agreement, related to the fact that Indemnitee is or was a director, officer, employee or agent of the Company or any subsidiary of the Company, or is or was serving at the request of the
Company as a director, officer, employee, member, manager, trustee or agent of any other corporation, limited liability company, partnership, joint venture, trust or other entity or enterprise (collectively with the Company,
“Enterprise”) or by reason of an action or inaction by Indemnitee in any such capacity (whether or not serving in such capacity at the time any Loss is incurred for which indemnification can be provided under this Agreement). 

(i) “Independent Counsel” means a law firm, or a member of a law firm, that is experienced in matters of
corporation law and neither presently performs, nor in the past five years has performed, services for either: (i) the Company or Indemnitee (other than in connection with matters concerning Indemnitee under this Agreement or of other
indemnitees under similar agreements) or (ii) any other party to the Claim giving rise to a claim for indemnification hereunder. Notwithstanding the foregoing, the term “Independent Counse” shall not include any person who, under the
applicable standards of professional conduct then prevailing, would have a conflict of interest in representing either the Company or Indemnitee in an action to determine Indemnitee’s rights under this Agreement. 

(j) “Losses” means any and all Expenses, damages, losses, liabilities, judgments, fines, penalties (whether
civil, criminal or other), ERISA excise taxes, amounts paid or payable in settlement, including any interest, assessments, any federal, state, local or foreign taxes imposed as a result of the actual or deemed receipt of any payments under this
Agreement (net of deductions attributable to such taxes paid) and all other charges paid or payable in connection with investigating, defending, being a witness in or participating in (including on appeal), or preparing to defend, be a witness or
participate in, any Claim. 
 (k) “Person” means any individual, corporation, firm, partnership, joint
venture, limited liability company, estate, trust, business association, organization, governmental entity or other entity and includes the meaning set forth in Sections 13(d) and 14(d) of the Exchange Act. 

(l) “Standard of Conduct Determination” shall have the meaning ascribed to it in Section 8(b) below. 

(m) “Voting Securities” means any securities of the Company that vote generally in the election of directors.

 2. Indemnification. Subject to Section 8 and Section 9 of this Agreement, the Company shall indemnify Indemnitee, to the
fullest extent permitted by the laws of the State of Delaware in effect on the date hereof, or as such laws may from time to time hereafter be amended to increase the scope of such permitted indemnification, against any and all Losses if Indemnitee
was or is or becomes a party to or participant in, or is threatened to be made a party to or participant in, any Claim by reason of or arising in part out of an Indemnifiable Event, including, without limitation, Claims brought by or in the right of
the Company, Claims brought by third parties, and Claims in which the Indemnitee is solely a witness. 

  
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 3. Advancement of Expenses. Indemnitee shall have the right to advancement by the
Company, prior to the final disposition of any Claim by final adjudication to which there are no further rights of appeal, of any and all Expenses actually and reasonably paid or incurred by Indemnitee in connection with any Claim arising out of an
Indemnifiable Event. Indemnitee’s right to such advancement is not subject to the satisfaction of any standard of conduct. Without limiting the generality or effect of the foregoing, Indemnitee shall submit to the Company a written request
therefor, including a brief description (based upon the information then available to the Indemnitee) of such Claim for which advancement is sought and the Expenses to be advanced. Unless otherwise agreed between the Company and the Indemnitee,
within thirty (30) days after the receipt by the Company of any written request by Indemnitee, the Company shall, in accordance with such request, (a) pay such Expenses on behalf of Indemnitee, (b) advance to Indemnitee funds in an
amount sufficient to pay such Expenses, or (c) reimburse Indemnitee for such Expenses. In connection with any request for Expense Advances, Indemnitee shall not be required to provide any documentation or information to the extent that the
provision thereof would undermine or otherwise jeopardize attorney-client privilege. In connection with any request for Expense Advances, Indemnitee shall execute and deliver to the Company an undertaking (which shall be accepted without reference
to the Indemnitee’s ability to repay the Expense Advances any amounts paid, advanced or reimbursed by the Company for such Expenses to the extent that it is ultimately determined, pursuant to Section 8, following the final disposition of
such Claim, that Indemnitee is not entitled to indemnification hereunder. Indemnitee’s obligation to reimburse the Company for Expense Advances shallb ensecured and no interest shall be charged thereon. 

4. Indemnification for Expenses in Enforcing Rights. To the fullest extent allowable under applicable law, the Company shall also
indemnify against, and, if requested by Indemnitee, shall advance to Indemnitee subject to and in accordance with Section 3, any Expenses actually and reasonably paid or incurred by Indemnitee in connection with any action or proceeding by
Indemnitee for (a) indemnification or reimbursement or advance payment of Expenses by the Company under any provision of this Agreement, or under any other agreement or provision of the Constituent Documents now or hereafter in effect relating
to Claims relating to Indemnifiable Events, and/or (b) recovery under any directors’ and officers’ liability insurance policies maintained by the Company. However, in the event that Indemnitee is ultimately determined not to be
entitled to such indemnification or insurance recovery, as the case may be, then all amounts advanced under this Section 4 shall be repaid. Indemnitee shall be required to reimburse the Company in the event that a final judicial determination
is made that such action brought by Indemnitee was frivolous or not made in good faith. 
 5. Partial Indemnity. If Indemnitee is
entitled under any provision of this Agreement to indemnification by the Company for a portion of any Losses in respect of a Claim related to an Indemnifiable Event but not for the total amount thereof, the Company shall nevertheless indemnify
Indemnitee for the portion thereof to which Indemnitee is entitled. 
 6. Notification and Defense of Claims. 

(a) Notification of Claims. Indemnitee shall notify the Company in writing as soon as practicable of any Claim which
could relate to an Indemnifiable Event or for which Indemnitee could seek Expense Advances, including a brief description (based upon information then available to Indemnitee) of the nature of, and the facts underlying, such Claim. If at the time of
the receipt of such notice, the Company has directors’ and officers’ liability insurance in effect under which coverage for Claims related to Indemnifiable Events is potentially available, the Company shall give prompt written notice to
the applicable insurers in accordance with the procedures set forth in the applicable policies. The Company shall provide to Indemnitee a copy 

  
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of such notice delivered to the applicable insurers, and copies of all subsequent correspondence between the Company and such insurers regarding the Claim, in each case substantially concurrently
with the delivery or receipt thereof by the Company. The failure by Indemnitee to timely notify the Company hereunder shall not relieve the Company from any liability hereunder, unless, and only to the extent that, such failure results in the
forfeiture by the Company of substantial defenses, rights or insurance coverage. 
 (b) Defense of Claims. The Company
shall be entitled to participate in the defense of any Claim relating to an Indemnifiable Event at its own expense and, except as otherwise provided below, to the extent the Company so wishes, it may assume the defense thereof with counsel
reasonably satisfactory to Indemnitee. After notice from the Company to Indemnitee of its election to assume the defense of any such Claim, the Company shall not be liable to Indemnitee under this Agreement or otherwise for any Expenses subsequently
directly incurred by Indemnitee in connection with Indemnitee’s defense of such Claim other than reasonable costs of investigation or as otherwise provided below. Indemnitee shall have the right to employ its own legal counsel in such Claim,
but all Expenses related to such counsel incurred after notice from the Company of its assumption of the defense shall be at Indemnitee’s own expense; provided, however, that if (i) Indemnitee’s employment of its own legal
counsel has been authorized by the Company, (ii) Indemnitee has reasonably determined that there may be a conflict of interest between Indemnitee and the Company in the defense of such Claim, (iii) after a Change in Control,
Indemnitee’s employment of its own counsel has been approved by the Independent Counsel or (iv) the Company shall not in fact have employed counsel to assume the defense of such Claim, then Indemnitee shall be entitled to retain its own
separate counsel (but not more than one law firm plus, if applicable, local counsel in respect of any such Claim) and all Expenses related to such separate counsel shall be borne by the Company. 

7. Procedure upon Application for Indemnification. In order to obtain indemnification pursuant to this Agreement, Indemnitee shall
submit to the Company a written request therefor, including in such request such documentation and information as is reasonably available to Indemnitee and is reasonably necessary to determine whether and to what extent Indemnitee is entitled to
indemnification following the final disposition of the Claim, provided that documentation and information need not be so provided to the extent that the provision thereof would undermine or otherwise jeopardize attorney-client privilege.
Indemnification shall be made insofar as the Company determines Indemnitee is entitled to indemnification in accordance with Section 8 below. 

8. Determination of Right to Indemnification. 

(a) Mandatory Indemnification; Indemnification as a Witness.  

(i) To the extent that Indemnitee shall have been successful on the merits or otherwise in defense of any Claim relating to an
Indemnifiable Event or any portion thereof or in defense of any issue or matter therein, including without limitation dismissal without prejudice, Indemnitee shall be indemnified against all Losses relating to such Claim in accordance with
Section 2 to the fullest extent allowable by law, and no Standard of Conduct Determination (as defined in Section 8(b)) shall be required. 

(ii) To the extent that Indemnitee’s involvement in a Claim relating to an Indemnifiable Event is to prepare to serve and
serve as a witness, and not as a party, the Indemnitee shall be indemnified against all Losses incurred in connection therewith to the fullest extent allowable by law and no Standard of Conduct Determination (as defined in Section 8(b)) shall
be required. 

  
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 (b) Standard of Conduct. To the extent that the provisions of
Section 8(a) are inapplicable to a Claim related to an Indemnifiable Event that shall have been finally disposed of, any determination of whether Indemnitee has satisfied any applicable standard of conduct under Delaware law that is a legally
required condition to indemnification of Indemnitee hereunder against Losses relating to such Claim and any determination that Expense Advances must be repaid to the Company (a “Standard of Conduct Determination”) shall be made as
follows: 
 (i) if no Change in Control has occurred, (A) by a majority vote of the Disinterested Directors, even if
less than a quorum of the Board, (B) by a committee of Disinterested Directors designated by a majority vote of the Disinterested Directors, even though less than a quorum or (C) if there are no such Disinterested Directors, by Independent
Counsel in a written opinion addressed to the Board, a copy of which shall be delivered to Indemnitee; and 
 (ii) if a
Change in Control shall have occurred, (A) if the Indemnitee so requests in writing, by a majority vote of the Disinterested Directors, even if less than a quorum of the Board or (B) otherwise, by Independent Counsel in a written opinion
addressed to the Board, a copy of which shall be delivered to Indemnitee. 
 Any and all Expenses incurred by Indemnitee in
cooperating with the person or persons making such Standard of Conduct Determination shall be borne by the Company (irrespective of the determination as to Indemnitee’s entitlement to indemnification) and the Company hereby indemnifies and
agrees to hold Indemnitee harmless therefrom. 
 (c) Making the Standard of Conduct Determination. The Company shall
use its reasonable best efforts to cause any Standard of Conduct Determination required under Section 8(b) to be made as promptly as practicable. If the person or persons designated to make the Standard of Conduct Determination under
Section 8(b) shall not have made a determination within 30 days after the later of (A) receipt by the Company of a written request from Indemnitee for indemnification pursuant to Section 7 (the date of such receipt being the
“Notification Date”) and (B) the selection of an Independent Counsel, if such determination is to be made by Independent Counsel, then Indemnitee shall be deemed to have satisfied the applicable standard of conduct;
provided that such 30-day period may be extended for a reasonable time, not to exceed an additional 30 days, if the person or persons making such determination in good faith requires such additional
time to obtain or evaluate information relating thereto. Notwithstanding anything in this Agreement to the contrary, no determination as to entitlement of Indemnitee to indemnification under this Agreement shall be required to be made prior to the
final disposition of any Claim. 
 (d) Payment of Indemnification. If, in regard to any Losses: 

(i) Indemnitee shall be entitled to indemnification pursuant to Section 8(a); 

  
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 (ii) no Standard Conduct Determination is legally required as a condition to
indemnification of Indemnitee hereunder; or 
 (iii) Indemnitee has been determined or deemed pursuant to Section 8(b)
or Section 8(c) to have satisfied the Standard of Conduct Determination, 
 then the Company shall pay to Indemnitee,
within five business days after the later of (A) the Notification Date or (B) the earliest date on which the applicable criterion specified in clause (i), (ii) or (iii) is satisfied, an amount equal to such Losses. 

(e) Selection of Independent Counsel for Standard of Conduct Determination. If a Standard of Conduct Determination is to
be made by Independent Counsel pursuant to Section 8(b)(i), the Independent Counsel shall be selected by the Board of Directors, and the Company shall give written notice to Indemnitee advising the Indemnitee of the identity of the Independent
Counsel so selected. If a Standard of Conduct Determination is to be made by Independent Counsel pursuant to Section 8(b)(ii), the Independent Counsel shall be selected by Indemnitee, and Indemnitee shall give written notice to the Company
advising it of the identity of the Independent Counsel so selected. In either case, Indemnitee or the Company, as applicable, may, within ten days after receiving written notice of selection from the other, deliver to the other a written objection
to such selection; provided, however, that such objection may be asserted only on the ground that the Independent Counsel so selected does not satisfy the criteria set forth in the definition of “Independent Counsel” in Section 1(i),
and the objection shall set forth with particularity the factual basis of such assertion. Absent a proper and timely objection, the person or firm so selected shall act as Independent Counsel. If such written objection is properly and timely made
and substantiated, (i) the Independent Counsel so selected may not serve as Independent Counsel unless and until such objection is withdrawn or a court has determined that such objection is without merit; and (ii) the non-objecting party may, at its option, select an alternative Independent Counsel and give written notice to the other party advising such other party of the identity of the alternative Independent Counsel so
selected, in which case the provisions of the two immediately preceding sentences, the introductory clause of this sentence and numbered clause (i) of this sentence shall apply to such subsequent selection and notice. If applicable, the
provisions of clause (ii) of the immediately preceding sentence shall apply to successive alternative selections. If no Independent Counsel that is permitted under the foregoing provisions of this Section 8(e) to make the Standard of
Conduct Determination shall have been selected within 30 days after the Company gives its initial notice pursuant to the first sentence of this Section 8(e) or Indemnitee gives its initial notice pursuant to the second sentence of this
Section 8(e), as the case may be, either the Company or Indemnitee may petition the Court of Chancery of the State of Delaware (“Delaware Court”) to resolve any objection which shall have been made by the Company or Indemnitee
to the other’s selection of Independent Counsel and/or to appoint as Independent Counsel a person to be selected by the Court or such other person as the Court shall designate, and the person or firm with respect to whom all objections are so
resolved or the person or firm so appointed will act as Independent Counsel. In all events, the Company shall pay all of the reasonable fees and expenses of the Independent Counsel incurred in connection with the Independent Counsel’s
determination pursuant to Section 8(b). 
 (f) Presumptions and Defenses.  

  
 7 

 (i) Indemnitee’s Entitlement to Indemnification. In making any
Standard of Conduct Determination, the person or persons making such determination shall presume that Indemnitee has satisfied the applicable standard of conduct and is entitled to indemnification, and the Company shall have the burden of proof to
overcome that presumption and establish that Indemnitee is not so entitled. Any Standard of Conduct Determination that is adverse to Indemnitee may be challenged by the Indemnitee in the Delaware Court. No determination by the Company (including by
its directors or any Independent Counsel) that Indemnitee has not satisfied any applicable standard of conduct may be used as a defense to any legal proceedings brought by Indemnitee to secure indemnification or reimbursement or advance payment of
Expenses by the Company hereunder or create a presumption that Indemnitee has not met any applicable standard of conduct. 

(ii) Reliance as a Safe Harbor. For purposes of this Agreement, and without creating any presumption as to a lack of
good faith if the following circumstances do not exist, Indemnitee shall be deemed to have acted in good faith and in a manner Indemnitee reasonably believed to be in or not opposed to the best interests of the Company if Indemnitee’s actions
or omissions to act are taken in good faith reliance upon the records of the Company, including its financial statements, or upon information, opinions, reports or statements furnished to Indemnitee by the officers or employees of the Company or any
of its subsidiaries in the course of their duties, or by committees of the Board or by any other Person (including legal counsel, accountants and financial advisors) as to matters Indemnitee reasonably believes are within such other Person’s
professional or expert competence and who has been selected with reasonable care by or on behalf of the Company. In addition, the knowledge and/or actions, or failures to act, of any director, officer, agent or employee of the Company shall not be
imputed to Indemnitee for purposes of determining the right to indemnity hereunder. 
 (iii) No Other Presumptions.
For purposes of this Agreement, the termination of any Claim by judgment, order, settlement (whether with or without court approval) or conviction, or upon a plea of nolo contendere or its equivalent, will not create a presumption that Indemnitee
did not meet any applicable standard of conduct or have any particular belief, or that indemnification hereunder is otherwise not permitted. 

(iv) Defense to Indemnification and Burden of Proof. It shall be a defense to any action brought by Indemnitee against
the Company to enforce this Agreement (other than an action brought to enforce a claim for Losses incurred in defending against a Claim related to an Indemnifiable Event in advance of its final disposition) that it is not permissible under
applicable law for the Company to indemnify Indemnitee for the amount claimed. In connection with any such action or any related Standard of Conduct Determination, the burden of proving such a defense or that the Indemnitee did not satisfy the
applicable standard of conduct shall be on the Company. 
 (v) Resolution of Claims. The Company acknowledges that a
settlement or other disposition short of final judgment may be successful on the merits or otherwise for purposes of Section 8(a)(i) if it permits a party to avoid expense, delay, distraction, disruption and uncertainty. In the event that any
Claim relating to an Indemnifiable Event to which Indemnitee is a party is resolved in any manner other than by adverse judgment against Indemnitee (including, without limitation, settlement of such action, claim or proceeding with our without
payment of money or other consideration) it shall be presumed that Indemnitee has been successful on the merits or otherwise for purposes of Section 8(a)(i). The Company shall have the burden of proof to overcome this presumption. 

  
 8 

 9. Exclusions from Indemnification. Notwithstanding anything in this Agreement to the
contrary, the Company shall not be obligated to: 
 (a) indemnify or advance funds to Indemnitee for Expenses or Losses with
respect to proceedings initiated by Indemnitee, including any proceedings against the Company or its directors, officers, employees or other indemnitees and not by way of defense, except: 

(i) proceedings referenced in Section 4 above (unless a court of competent jurisdiction determines that each of the
material assertions made by Indemnitee in such proceeding was not made in good faith or was frivolous); or 
 (ii) where the
Company has joined in or the Board has consented to the initiation of such proceedings. 
 (b) indemnify Indemnitee if a
final decision by a court of competent jurisdiction determines that such indemnification is prohibited by applicable law. 

(c) indemnify Indemnitee for the disgorgement of profits arising from the purchase or sale by Indemnitee of securities of the
Company in violation of Section 16(b) of the Exchange Act, or any similar successor statute. 
 (d) indemnify or advance
funds to Indemnitee for Indemnitee’s reimbursement to the Company of any bonus or other incentive-based or equity-based compensation previously received by Indemnitee or payment of any profits realized by Indemnitee from the sale of securities
of the Company, as required in each case under the Exchange Act (including any such reimbursements under Section 304 of the Sarbanes-Oxley Act of 2002 in connection with an accounting restatement of the Company or the payment to the Company of
profits arising from the purchase or sale by Indemnitee of securities in violation of Section 306 of the Sarbanes-Oxley Act). 
 10.
Settlement of Claims. The Company shall not be liable to Indemnitee under this Agreement for any amounts paid in settlement of any threatened or pending Claim related to an Indemnifiable Event effected without the Company’s prior written
consent, which shall not be unreasonably withheld; provided, however, that if a Change in Control has occurred, the Company shall be liable for indemnification of the Indemnitee for amounts paid in settlement if an Independent Counsel has
approved the settlement. The Company shall not settle any Claim related to an Indemnifiable Event in any manner that would impose any Losses on the Indemnitee without the Indemnitee’s prior written consent. 

11. Duration. All agreements and obligations of the Company contained herein shall continue during the period that Indemnitee is a
director or officer of the Company (or is serving at the request of the Company as a director, officer, employee, member, trustee or agent of another Enterprise) and shall continue thereafter (i) so long as Indemnitee may be subject to any
possible Claim relating to an Indemnifiable Event (including any rights of appeal thereto) and (ii) throughout the pendency of any proceeding (including any rights of appeal thereto) commenced by Indemnitee to enforce or interpret his or her
rights under this Agreement, even if, in either case, he or she may have ceased to serve in such capacity at the time of any such Claim or proceeding. 

  
 9 

 12. Non-Exclusivity. The rights of Indemnitee
hereunder will be in addition to any other rights Indemnitee may have under the Constituent Documents, the General Corporation Law of the State of Delaware, any other contract or otherwise (collectively, “Other Indemnity
Provisions”); provided, however, that (a) to the extent that Indemnitee otherwise would have any greater right to indemnification under any Other Indemnity Provision, Indemnitee will be deemed to have such greater right
hereunder and (b) to the extent that any change is made to any Other Indemnity Provision which permits any greater right to indemnification than that provided under this Agreement as of the date hereof, Indemnitee will be deemed to have such
greater right hereunder. The Company will not adopt any amendment to any of the Constituent Documents the effect of which would be to deny, diminish or encumber Indemnitee’s right to indemnification under this Agreement or any Other Indemnity
Provision. For the avoidance of doubt, nothing hereunder shall reduce, diminish, abrogate or otherwise limit any rights to indemnification, exculpation or recovery to which Indemnitee may be entitled unde the laws of any other jurisdiction. 

13. Liability Insurance. For the duration of Indemnitee’s service as a [director/officer] of the Company, and thereafter for so
long as Indemnitee shall be subject to any pending Claim relating to an Indemnifiable Event, the Company shall use commercially reasonable efforts (taking into account the scope and amount of coverage available relative to the cost thereof) to
continue to maintain in effect policies of directors’ and officers’ liability insurance providing coverage that is at least substantially comparable in scope and amount to that provided by the Company’s current policies of
directors’ and officers’ liability insurance. In all policies of directors’ and officers’ liability insurance maintained by the Company, Indemnitee shall be named as an insured in such a manner as to provide Indemnitee the same
rights and benefits as are provided to the most favorably insured of the Company’s directors, if Indemnitee is a director, or of the Company’s officers, if Indemnitee is an officer (and not a director) by such policy. Upon request, the
Company will provide to Indemnitee copies of all directors’ and officers’ liability insurance applications, binders, policies, declarations, endorsements and other related materials. 

14. No Duplication of Payments. The Company shall not be liable under this Agreement to make any payment to Indemnitee in respect of any
Losses to the extent Indemnitee has otherwise received payment under any insurance policy, the Constituent Documents, Other Indemnity Provisions or otherwise of the amounts otherwise indemnifiable by the Company hereunder. 

15. Subrogation. In the event of payment to Indemnitee under this Agreement, the Company shall be subrogated to the extent of such
payment to all of the rights of recovery of Indemnitee. Indemnitee shall execute all papers required and shall do everything that may be necessary to secure such rights, including the execution of such documents necessary to enable the Company
effectively to bring suit to enforce such rights. 
 16. Amendments. No supplement, modification or amendment of this Agreement shall
be binding unless executed in writing by both of the parties hereto. No waiver of any of the provisions of this Agreement shall be binding unless in the form of a writing signed by the party against whom enforcement of the waiver is sought, and no
such waiver shall operate as a waiver of any other provisions hereof (whether or not similar), nor shall such waiver constitute a continuing waiver. Except as specifically provided herein, no failure to exercise or any delay in exercising any right
or remedy hereunder shall constitute a waiver thereof. 

  
 10 

 17. Binding Effect. This Agreement shall be binding upon and inure to the benefit of
and be enforceable by the parties hereto and their respective successors (including any direct or indirect successor by purchase, merger, consolidation or otherwise to all or substantially all of the business and/or assets of the Company), assigns,
spouses, heirs and personal and legal representatives. The Company shall require and cause any successor (whether direct or indirect by purchase, merger, consolidation or otherwise) to all, substantially all or a substantial part of the business
and/or assets of the Company, by written agreement in form and substances satisfactory to Indemnitee, expressly to assume and agree to perform this Agreement in the same manner and to the same extent that the Company would be required to perform if
no such succession had taken place. 
 18. Severability. The provisions of this Agreement shall be severable in the event that any of
the provisions hereof (including any portion thereof) are held by a court of competent jurisdiction to be invalid, illegal, void or otherwise unenforceable, and the remaining provisions shall remain enforceable to the fullest extent of the law. Upon
such determination that any term or other provision is invalid, illegal or unenforceable, the parties hereto shall negotiate in good faith to modify this Agreement so as to effect the original intent of the parties as closely as possible in a
mutually acceptable manner in order that the transactions contemplated hereby be consummated as originally contemplated to the greatest extent possible. 

19. Notices. All notices, requests, demands and other communications hereunder shall be in writing and shall be deemed to have been duly
given if delivered by hand, against receipt, or mailed, by postage prepaid, certified or registered mail: 
 (a) if to
Indemnitee, to the address set forth on the signature page hereto. 
 (b) if to the Company, to: 

Tyme Technologies, Inc. 

Attn: [OFFICER] 

1 Pluckemin Way, Suite 103 

Bedminster, NJ 07921 

Notice of change of address shall be effective only when given in accordance with this Section. All notices complying with this Section shall
be deemed to have been received on the date of hand delivery or on the third business day after mailing. 
 20. Governing Law and
Forum. This Agreement shall be governed by and construed and enforced in accordance with the laws of the State of Delaware applicable to contracts made and to be performed in such state without giving effect to its principles of conflicts of
laws. The Company and Indemnitee hereby irrevocably and unconditionally: (a) agree that any action or proceeding arising out of or in connection with this Agreement shall be brought only in the Delaware Court and not in any other state or
federal court in the United States, (b) consent to submit to the exclusive jurisdiction of the Delaware Court for purposes of any action or proceeding arising out of or in connection with this Agreement and (c) waive, and agree not to
plead or make, any claim that the Delaware Court lacks venue or that any such action or proceeding brought in the Delaware Court has been brought in an improper or inconvenient forum. 

  
 11 

 21. Headings. The headings of the sections and paragraphs of this Agreement are
inserted for convenience only and shall not be deemed to constitute part of this Agreement or to affect the construction or interpretation thereof. 

22. Counterparts. This Agreement may be executed in one or more counterparts, each of which shall for all purposes be deemed to be an
original, but all of which together shall constitute one and the same Agreement. 
 [SIGNATURE PAGE FOLLOWS] 

  
 12 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	TYME TECHNOLOGIES, INC.
	
	By:                                     
                                         
                  
	Name:
	Title:
	
	INDEMNITEE
	
	  

	Name:
	Address:                                     
                                         
        
	  

	  

 [Signature Page to Indemnification Agreement] 

  
 13

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