Document:

Exhibit 10.1

    * Certain portions of this exhibit have been omitted pursuant
      to a request for confidential treatment and those portions have been filed
      separately with the Securities and Exchange Commission.

    
 

    AMENDMENT
      TO DISTRIBUTION AGREEMENT

    

    This
      AMENDMENT TO DISTRIBUTION AGREEMENT (this "Amendment') is made and entered
      into
      as of December 13 2006, by and among SKINVISIBLE PHARMACEUTICALS, INC., a Nevada
      corporation ("Skinvisible"), DERMAL DEFENSE, INC., a Nevada
      corporation
      ("DDI”) and JD NELSON & ASSOCIATES, LLC, an Ohio limited liability company
      ("JDN")
      (Skinvisible, DIM and JDN are collectively referred to as the
      "Parties").

    

    RECITALS

    WHEREAS,
      Skinvisible and DDI previously entered into a Distribution Agreement
(the
      "Agreement") dated
      as
      of February 21, 2005 whereby Skinvisible granted DDI the right to manufacture,
      distribute,
      market,
      sell and promote the Product
      throughout
      the Territory;

    

    WHEREAS,
      pursuant to the
      terms
      of the Agreement, DDI appointed JDN as a sub-distributor
      under the Agreement as documented by the Distribution Agreement (the "JDN
      Agreement") between DDI and JDN dated as of April 28, 2005;

    

    WHEREAS,
      DDI and JDN have amended and restated the terms of the JDN Agreement in its
      entirety pursuant to the Amended and Restated Distribution Agreement (the
      "Amended JDN Agreement") dated as of July 1, 2006; and

    

    WHEREAS,
      the Parties wish to
      enter
      into this Amendment to amend the terms of the Agreement
      as provided herein and
      to
      grant certain rights and to impose certain obligations upon JDN
      as
      provided herein.

    

    NOW,
      THEREFORE, in
      consideration of the mutual promises contained herein and other good and
      valuable consideration, the receipt and sufficiency of which is hereby
      acknowledged, the Parties hereto agree as follows:

    

    AGREEMENTS

    

    
      	1.  	
              Incorporation
                of Recitals.
                The Parties acknowledge that the foregoing Recitals are true and
                correct
                and are incorporated herein as material terms of this
                Amendment.

            

    

    

    
      	2.  	
              Definitions.
                Capitalized terms not defined herein shall have the meanings assigned
                to
                them in the Agreement.

            

    

    

    
      	3.  	
              Definition
                of Product. Section 1.5 of the Agreement is amended and restated in
                its entirety as follows:

            

    

    

    "Product"
      means
      Skinvisible's proprietary antimicrobial hand sanitizer product incorporating
      the
      active ingredient Triclosan and any the other
      active ingredients included in the US FDA Monograph (see Schedule A), exclusive
      of Chlorhexidine,

    gltuconate
      or iodine or any combinations of iodine or

    Chlorhexidine
      gluconate or Chlorhexidine.

    .

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    
      	4.  	
              Exclusivity.

            

    

    

     4.1
       Skinvisible.
      Skinvisible
      agrees and acknowledges that
      so
      long as the Agreement is
      in
      effect it shall not market or sell, or grant a Party other than DDI the right
      to
      market and sell, within
      the Territory the Product.

    

     4.2  DDI.  DDI
      agrees
      and acknowledges that so long as the Amended JDN Agreement is in effect it
      shall
      not market or sell, or grant a Party other than JDN the right to market and
      sell, within the Territory the Product. Skinvisible hereby consents to the
      grant
      of exclusivity by DDI to JDN as provided in this Section 4.2.

    

    
      	5.  	
              Royalty
                Obligations of DDI.       
                * 

            

    

    

    

    
      	6.  	
              Royalty
                Payment by
                JDN.           *

            

    

     

    
      	7.  	
              Rights
                and Obligations of JDN. The
                Parties
                agree and acknowledge that JDN shall be permitted to manufacture
                the
                Product as such right is granted to DDI pursuant to the Agreement
                as
                amended by
                this Amendment.
                JDN
                shall be entitled to transact directly with Skinvisible for ordering
                and
                payment related to
                raw materials such as polymer and related supplies. JDN shall be
                entitled
                to negotiate directly
                with
                Skinvisible for the pricing of raw materials and supplies. JDN shall
                be
                responsible for the payment for all JDN purchases from
                Skinvisible-
                The rights granted to JDN are limited to those explicitly set forth
                in
                this Section 7, JDN agrees and acknowledges
                that:

            

    

     

    7.1 JDN
      shall
      indemnify and hold DDI and Skinvisible harmless for any breach by

    JDN
      of
      the Agreement or this Amendment;

    

    
      
        *
          The
          confidential portion has been omitted and filed separately with the Securities
          and Exhange Commission

      

      
        2

        
          

        

      

      
        
        

      

    

     

    7.2
       Other
      than negotiations with Skinvisible regarding pricing of raw materials, supplies
      or the Product, JDN shall not enter into any Agreement with Skinvisible amending
      any provision of the Agreement or Amendment without the prior written approval
      of DDI.

    

    7.3  A
      breach
      by JDN of this Section 7,
      the
      Agreement or this Amendment shall be deemed
      a
breach
      by
      JDN of
      the Amended
      JDN Agreement which shall entitle DDI to exercise all of
      DDI's
      rights under the Amended
      JDN Agreement.

    

    7.4 
      A breach
      by JDN of this Section 7, the Agreement or this Amendment shall entitle
      Skinvisible to exercise its remedies under the
      Agreement against JDN including a termination of the rights granted to JDN
      under
      the Amended JDN Agreement and this Amendment; provided however, a breach by
      JDN
      shall not be deemed a breach by DDI of its obligations under the Agreement
      or
      the Amendment. Notwithstanding any rights that Skinvisible may have against
      JDN
      for any breach of this Section 7, DDI shall be primarily liable and Skinvisible
      shall be entitled to recover any damages incurred as a result of a breach by
      JDN
      of the provisions of this Section 7.

    

    
      	8.  	
              Notice
                of JDN Breach.
                Skinvisible agrees that it shall notify DDI of any breach by JDN
                of the
                Agreement and/or this Amendment, including without limitation the
                obligation to pay royalty fees pursuant to Section
                6.

            

    

    

    
      	9.  	
              Miscellaneous.

            

    

    

    9.1  Controlling
      Language, Reaffirmation.
      To
the
      extent any term(s)
      or
      condition(s) in
      the
      Agreement shall
      contradict
      or
      be
      in
      conflict
      with
      the
      amended terms
      as
      set
      forth
      in
      this
Amendment,
      such terms and conditions are hereby deemed modified and amended
      accordingly,
      upon the
      effective date hereof, to reflect the terms as so amended herein. All terms
      of
      the Agreement,
      as amended hereby, shall be and remain in full force and effect and shall
      constitute the
      legal, valid, binding and enforceable obligations of the Parties hereto. As
      of
      the date of this Amendment,
      the Parties herein restate, ratify and reaffirm each and every term and
      condition set forth
      in
      the Agreement and the Amended JDN Agreement as amended herein. There are no
      other changes
      to the Agreement and the Amended JDN Agreement except for the changes
      specifically set
      forth
      herein. Notwithstanding the foregoing, each Party acknowledges and agrees that
      in addition
      to amending certain terms and conditions of the Agreement and the Amended
      JDN Agreement,
      this Amendment restates certain terms and conditions previously set forth in
      the
      Agreement and the Amended JDN Agreement. Any terms or conditions set forth
      in
      the Agreement
      and the Amended JDN Agreement that are nut specifically amended or modified
      by this
      Amendment, even if not specifically restated herein, shall remain binding on
      the
      Parties
      hereto.

    

    9.2
       Consent
      to Amendments. 
      The
      provisions of this Amendment may be amended only
      by
      the written agreement of all of the Parties hereto. Any waiver, permit, consent
      or approval
      of any kind or character on the part of any Party of any provisions or
      conditions of this Amendment
      must he made in writing and will be effective only to the extent specifically
      set forth in
      such
      writing. No Party may assign its rights hereunder without written consent of
      the
      other Parties,
      and no such assignment shall relieve a Party of its obligations
      hereunder.

    

    
      
        
        

      

      
        3

        
          

        

      

      
        
        

      

    

     

    9.3
       Severability.
      Whenever
      possible, each provision of this Amendment will be interpreted
      in such manner as to be effective and valid under applicable law,
      but
      if
      any provision
      of this
      Amendment is held to be prohibited by or invalid under applicable law, such
      provision will be ineffective only to the extent of such prohibition or
      invalidity, without invalidating the remainder of this Amendment.

    

    9.4
       Binding
      Effect. This
      Amendment will be binding
      upon
      and
      inure to the benefit of and be enforceable against
      the Parties hereto and their respective heirs, legal
      representatives,
      successors
      and assigns.

    

    9.5
       Governing
      Law.
      This
      Amendment will in all respects be governed by, and enforced and interpreted
      in
      accordance with the substantive law of, without regard to the law of conflicts
      of the State of Nevada. Any dispute arising from
      or
      related to this Amendment shall be decided by the courts sited in Clark County,
      Nevada, to the exclusion of all other venues.

    

    9.6 Headings. Section
      and article headings used in this Amendment have no legal significance and
      are
      used solely for convenience of reference,

    

    9.7
       Counterparts. This
      Amendment may be executed in counterparts, each which will he
      deemed
      an
      original and all of which, taken together, will constitute one
      instrument.

    

    9.8 Attorneys
      Fees.
      The
      prevailing Party in any action brought pursuant to this

    Amendment
      shall be entitled to recover its reasonable attorneys' fees
      and
      court
      costs.

    

    IN
      WITNESS WHEREOF, the Parties have executed this Amendment as of the date
      first
      set
      forth above.

    

    SKINVISIBLE
      PHARMACEUTICALS, INC.

    /s/
      Terry Howlett

    By:
      Terry
      Howlett
      

    Its.
      President

    

    DERMAL
      DEFENSE, INC.

    

    /s/
      G.
      Michael Cronk

    By:
      G.
      Michael Cronk

    Its:
      President & CEO

    

    JD
      NELSON
& ASSOCIATES, LLC

    

    /s/
      J.
      Douglas Nelson

    By:
      J.
      Douglas Nelson

    Its:
      President

     

    
      
        
        

      

      
        4Exhibit 10.2

    EMPLOYMENT
      AGREEMENT

    

    

    THIS
      AGREEMENT made
      as
      of January 1, 2006

    

    BETWEEN:

    

    SKINVISIBLE,
      INC. 

    6320
      S. Sandhill Rd., Suite 10

    Las
      Vegas, Nevada 89120

    

    (The
      “Corporation”)

    

    OF
      THE FIRST PART

    

    AND

    

    TERRY
      HOWLETT

    464
      Beardsley Circle

            Henderson,
      Nevada 89052

    

    (The
      “Employee”)

    

    OF
      THE SECOND PART

    

    WHEREAS:

    

    
      	A.  	
              The
                Corporation wishes to renew the services of the Employee as President
                and
                Chief Executive Officer of the Corporation upon the terms and conditions
                of this agreement.

            

    

    

    
      	B.  	
              The
                Employee has agreed to provide such services as an Employee upon
                the terms
                and conditions hereinafter set
                forth.

            

    

    

    NOW
      THIS AGREEMENT WITNESSES that
      in
      consideration of the mutual promises, covenants and agreements herein contained,
      the parties hereto agree as follows:

    

    
      	1.  	
              Engagement
                of Employee

            

    

    

    
      	1.1  	
              The
                Corporation hereby engages the Employee as President and Chief Executive
                Officer of the Corporation and the Employee hereby accepts such
                employment.

            

    

    

    
      	1.2  	
              The
                Employee shall perform all such acts and do all such things as and
                when
                the same may be necessary to properly and efficiently carry out the
                duties
                of President and Chief Executive Officer of the Corporation which
                duties
                shall include but shall not be limited
                to:

            

    

    

    
      	(a)  	
              exercising
                general direction and supervision over all activities of the
                Corporation;

            

    

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    
      	(b)  	
              performing
                such other duties and observing such instructions as may be reasonably
                assigned to him from time to time in his capacity of President and
                Chief
                Executive Officer by the Board of Directors;
                and

            

    

    

    
      	(c)  	
              generally
                at all times abiding by all lawful directions given him by the Board
                of
                Directors of the Corporation.

            

    

    

    
      	1.3  	
              The
                Employee shall at all times use its best effort to advance the interests
                of the Corporation, and shall faithfully, industriously, and to the
                best
                of its abilities, act as an employee of the Corporation in accordance
                with
                the terms and conditions of this
                Agreement.

            

    

    

    
      	1.4  	
              The
                Employee warrants and represents to the Corporation that the Employee
                is
                not party to any agreement or subject to any court order which would
                prevent the Employee from providing the Consulting
                Services.

            

    

    

    
      	2.  	
              Remuneration

            

    

    

    
      	2.1  	
              The
                Company shall pay the Employee a gross salary (before standard deductions)
                of $13,333.33 per month (the “Salary”) in consideration of the duties
                performed by the Employee. The Company shall make all payments in
                respect
                of the Salary to the Employee in equal installments on a bi-weekly
                basis
                commencing on the first payroll date of the Company after the date
                hereof.
                The Employee’s Salary shall be reviewed on an annual basis in each year of
                this Agreement during the term of this
                Agreement.

            

    

    

    
      	2.2  	
              The
                Company shall reimburse the Employee for reasonable travelling and
                other
                expenses actually and properly incurred by the Employee in carrying
                out
                his duties hereunder, provided that such expenses are supported by
                proper
                receipts, invoices or vouchers supplied to the Company. The Company
                will
                provide the Employee with an automobile to be leased and the Company
                will
                reimburse the Employee for reasonable automobile expenses. The company
                shall also reimburse the Employee for living expenses not to exceed
                $2,000
                per month. 

            

    

    

    
      	2.3  	
              The
                Employee agrees to perform his duties on a continuous and full-time
                basis,
                provided that the Employee shall be entitled on reasonable prior
                written
                notice to 4 (four) weeks annual vacation during each year of the
                term of
                this Agreement. In the event the Employee is not able to take the
                vacation
                as earned he may elect to receive the vacation time in pay or extend
                to
                the next year.

            

    

    

    
      	2.4  	
              The
                Employee will be entitled to stock options to purchase shares of
                the
                Company to be granted at the discretion of the Board of Directors
                of the
                Company.

            

    

    

    
      	3.  	
              Term
                of Employment

            

    

    

    
      	3.1  	
              The
                initial term of this Agreement shall be three (3) years, commencing
                on the
                date of first written above, subject to earlier termination as hereinafter
                provided.

            

    

    

    
      
        
        

      

      
        2

        
          

        

      

      
        
        

      

    

     

    
      	4.  	
              Confidentiality
                and Non-Competition

            

    

    

    
      	4.1  	
              The
                Employee shall not, either during the term of this Agreement or any
                time
                thereafter, disclose to any person any confidential information concerning
                the business or affairs of the Corporation which the Employee may
                have
                acquired in the course of or incidental to his employment hereunder
                or
                otherwise, and the Employee shall not directly use (whether for his
                own
                benefit or the detriment or intended detriment of the Corporation)
                any
                confidential information he may acquire with respect to the business
                and
                affairs of the Corporation.

            

    

    

    
      	4.2  	
              The
                Employee agrees with the Corporation that he will not, either alone
                or in
                conjunction with any individual firm, corporation, association or
                other
                entity, whether as principal, agent, director, officer, employee,
                shareholder or in any other capacity
                whatsoever:

            

    

    

    
      	(a)  	
              during
                the term of this Agreement and for a one year period from the termination
                of this Agreement, carry on, or be engaged in, concerned with or
                interested in, directly or indirectly, any business which is in whole
                or
                in part competitive with the business of the
                Corporation;

            

    

    

    
      	(b)  	
              during
                the term of this Agreement and for a one year period from the termination
                of this Agreement, attempt to solicit any suppliers, customers or
                employees of the business of the Corporation away from the
                Corporation;

            

    

    

    
      	(c)  	
              during
                the term of this Agreement and for a one year period from the termination
                of this Agreement, knowingly take any act as a result of which the
                relations between the Corporation and the suppliers or customers
                of the
                business of the Corporation may be impaired or which may otherwise
                be
                detrimental to the business of the
                Corporation.

            

    

    

    
      	5.  	
              Assignment
                of Inventions

            

    

    

    
      	5.1  	
              Any
                and all inventions and improvements on which the Employee may conceive
                or
                make, during the term of this Agreement, relating, or in any way,
                pertaining to or connected with any of the matters which have been,
                are or
                may become the subject of the Corporation’s investigations, or in which
                the Corporation has been, is, or may become interested, shall be
                the sole
                and exclusive property of the Corporation, and the Employee will,
                whenever
                requested by the Corporation, execute any and all applications,
                assignments and other instruments which the Corporation shall deem
                necessary in order to apply for and obtain letters of patent for
                U.S. or
                foreign countries for the inventions or improvements and in order
                to
                assign and convey to the Corporation the sole and exclusive right,
                title
                and interest in and to the inventions or improvements, all expenses
                in
                connection with them to be borne by the Corporation. The Employee’s
                obligations to execute the papers referred to in this paragraph shall
                continue beyond the termination of this Agreement with respect to
                any and
                all inventions or improvements conceived or made by him during the
                term of
                this Agreement, and the obligations shall be binding on the assigns,
                executors, administrators or other legal representatives of the
                Employee.

            

    

    

    
      
        
        

      

      
        3

        
          

        

      

      
        
        

      

       

    

    
      	5.2  	
              All
                inventions and discoveries relating to the business of the Corporation
                and
                all knowledge and information which the Employee may acquire during
                his
                engagement shall be held by the Employee in trust for the benefit
                of the
                Corporation.

            

    

    

    
      	6.  	
              Termination

            

    

    

    
      	6.1  	
              The
                Corporation may terminate this Agreement at any time for just cause,
                provided that reasonable warning shall have been first given by the
                Corporation to the Employee and provided that those obligations of
                the
                Employee in this Agreement expressly stated to continue on termination
                shall continue upon termination and shall not terminate upon termination
                of this Agreement.

            

    

    

    
      	6.2  	
              The
                Employee may terminate this Agreement at any time upon three months
                written notice to the Corporation, provided that those obligations
                of the
                Employee in this Agreement expressly stated to continue on termination
                shall continue upon termination and shall not terminate upon termination
                of this Agreement.

            

    

    

    
      	7.  	
              Notices

            

    

    

    
      	7.1  	
              Any
                notice required or permitted to be given under this Agreement shall
                be in
                writing and may be delivered personally or by telecopier, or by pre-paid
                registered post addressed to the parties at the above-mentioned addresses
                or at such address of which notice may be given by either of such
                parties.
                Any notice shall be deemed to have been received if personally delivered
                or by telex or telecopier, on the date of delivery and, if mailed
                as
                aforesaid, then on the fourth business day after and excluding the
                day of
                mailing.

            

    

    

    
      	8.  	
              Assignment

            

    

    

    
      	8.1  	
              This
                Agreement may not be assigned in whole or in party by the Employee
                without
                the prior written consent of the
                Corporation.

            

    

    

    
      	8.2  	
              This
                Agreement may not be assigned in whole or in part by the Corporation
                without the prior written consent of the
                Employee.

            

    

    

    
      	9.  	
              Interpretation

            

    

    

    
      	9.1  	
              This
                Agreement shall be governed by and construed in accordance with the
                laws
                of the State of Nevada.

            

    

    

    
      	9.2  	
              All
                headings used in this Agreement are for convenience of reference
                only and
                are not to be used as an aid in the interpretation of this
                Agreement.

            

    

    

    
      	9.3  	
              This
                Agreement replaces and supercedes all other contracts, including
                consulting agreements and employment agreements, between the Employee
                and
                the Corporation.

            

    

    

    
      
        
        

      

      
        4

        
          

        

      

      
        
        

      

    

    

    IN
      WITNESS WHEREOF the
      parties have executed this Agreement as of the day and year first above
      written.

    

    SKINVISIBLE,
      INC. 

    

    

    By
      it’s
      authorized signatory:

     

    
      	By: 	/s/ Terry Howlett	 	/s/ Jost
              Steinbruchel
	
              Its:

               

            	
              Terry
                Howlett

              President

            	 	
              Jost
                Steinbruchel

              Director

            
	 	 	 	 
	By:	/s/ Greg
              McCartney	 	 
	 	
              Greg
                McCartney

              Director  

            	 	 

    

     

    
      	SIGNED, SEALED
              AND
              DELIVERED	)	 
	BY: Terry
              Howlett	)	 
	 	 	 
	In the presence of: 	)	 
	 	)	 
	_______________	)	/s/ Terry Howlett
	 	) 	Terry
              Howlett

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