Document:

EX-10.36

 Exhibit 10.36 

***Text Omitted and Filed Separately with the Securities and Exchange Commission. 

Confidential Treatment Requested Under 

17 C.F.R. Sections 200.80(b)(4) and 240.24b-2 

SECOND AMENDMENT TO LEASE 

(Corporate 500 Centre) 

THIS SECOND AMENDMENT TO LEASE (“Second Amendment”) is made and entered into as of the 10th day of December, 2013, by and between LONG RIDGE OFFICE PORTFOLIO, L.P., a Delaware limited partnership (“Landlord”), and HORIZON PHARMA USA, INC., a Delaware corporation
(“Tenant”). 
 RECITALS 

A.     Landlord and Tenant entered into that certain Standard Office Lease dated as of
August 2, 2011 (the “Original Lease”), whereby Tenant leases certain office space located in that certain building located and addressed at 520 Lake Cook Road, Deerfield, Illinois 60015 (the “Building”). The
Original Lease was subsequently amended by that certain First Amendment to Lease dated July 31, 2012, by and between Landlord and Tenant (the “First Amendment”). The Original Lease, as amended by the First Amendment, shall be
referred to herein as the “Lease.” 
 B.     By this Second Amendment, Landlord
and Tenant desire that Tenant lease additional space within the Building, and to otherwise modify the Lease as provided herein. 

C.     Unless otherwise defined herein, capitalized terms shall have the meanings given such terms in the
Lease. 
 NOW, THEREFORE, in consideration of the foregoing recitals and the mutual covenants contained herein, and for
other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto hereby agree as follows: 

AGREEMENT 

1.     Existing Premises.   Landlord and Tenant hereby acknowledge that Tenant currently
leases from Landlord (a) that certain office space in the Building containing 4,926 rentable square feet located on the third (3rd) floor of the Building and known as Suite 350, and
(b) that certain office space in the Building containing 21,182 rentable square feet located on the fifth (5th) floor of the Building and known as Suites 520 and 550 (collectively the
“Existing Premises”). 
 2.     Second Expansion Space.   That
certain space located on the third (3rd) floor of the Building known as Suite 375, as outlined on the floor plan attached hereto as EXHIBIT A, shall be referred to herein as the
“Second Expansion Space.” Landlord and Tenant hereby stipulate that the Second Expansion Space contains 8,352 rentable square feet. Tenant shall commence to pay charges with regard to the Second Expansion Space effective as of
May 1, 2014 (“Second Expansion Commencement Date”). The addition of the Second Expansion Space to the Existing Premises shall, effective as of the Second Expansion Commencement Date, increase the number of rentable square feet
leased by Tenant in the Building to a total of 34,460 rentable square feet. Effective as of the Second Expansion Commencement Date, all references to the “Premises” shall mean and refer to the Existing Premises as expanded by the Second
Expansion Space. 
 3.     Second Expansion Space Term.   The Term for
Tenant’s lease of the Second Expansion Space (“Second Expansion Space Term”) shall commence on the Second Expansion Commencement Date and shall expire co-terminously with Tenant’s lease of the Existing Premises on
June 30, 2018 (the “Expiration Date”). Tenant shall have the right to extend the Second Expansion Space Term beyond the Expiration Date under the terms and conditions set forth in Section 31 of the Original Lease and
Section 10 below. 
 Notwithstanding anything to the contrary contained herein, Tenant shall have the right to
commence business from the Second Expansion Space during the period (the “Beneficial Occupancy Period”) from the date of Landlord’s delivery of possession of the Second Expansion Space to Tenant until the Second Expansion
Commencement Date, provided that (i) Tenant shall give Landlord at least ten (10) days prior notice of any such occupancy of the Second Expansion Space, (ii) a certificate of occupancy (or its equivalent) shall have been issued by the
appropriate governmental authorities for the Second Expansion Space, and (iii) all of the terms and conditions of the Lease, as amended hereby, shall apply, including Tenant’s obligation to pay parking fees pursuant to Article 9
below, during the Beneficial Occupancy Period (if any), except that Tenant’s obligation to pay monthly Basic Rental and any Direct Costs shall not apply during the Beneficial Occupancy Period. 

  
 1 

 4.     Basic Rental.   Notwithstanding
anything to the contrary in the Lease, during the Second Expansion Space Term, Tenant shall pay, in accordance with the applicable provisions of the Lease and this Section 4, monthly installments of Basic Rental for the Second Expansion Space
as follows: 
  

					
	 	 	 
	Lease Period	 	Monthly Basic Rental	 	 Annual Basic
Rental per
 Rentable Square Foot

	 	 	 
	 May 1, 2014
– November 30, 2014  
	 	*$12,354.00	 	$17.75
	 	 	 
	
December 1, 2014 – November 30, 2015  
	 	$12,702.00	 	$18.25
	 	 	 
	 December 1,
2015 – November 30, 2016  
	 	$13,050.00	 	$18.75
	 	 	 
	 December 1,
2016 – November 30, 2017  
	 	$13,398.00	 	$19.25
	 	 	 
	 December 1,
2017 – June 30, 2018  
	 	$13,746.00	 	$19.75

 *Subject to the terms of Section 5 below, Tenant’s obligation to pay monthly Basic Rental and
Tenant’s Proportionate Share of Direct Costs for the Second Expansion Space shall be conditionally abated with respect to each of the full calendar months of June 2014 through and including the month of September 2014. 

5.     Conditional Abatement of Basic Rental and Direct Costs.   Notwithstanding anything
to the contrary contained in either the Lease or this Second Amendment, provided that Tenant faithfully performs all of the terms and conditions of the Lease, as hereby amended, through the date monthly Basic Rental and Tenant’s Proportionate
Share of Direct Costs would otherwise become due for the Second Expansion Space, Landlord hereby agrees to fully abate Tenant’s obligation to pay monthly Basic Rental and Tenant’s Proportionate Share of Direct Costs for the Second
Expansion Space for each of the full calendar months of June 2014 through and including the month of September 2014. The total amount of Basic Rental and Direct Costs so abated may be referred to herein as the “Abatement Amount.”
During such abatement periods, Tenant shall remain responsible for the payment of all of its other monetary obligations under the Lease, as hereby amended. However, in the event of a default by Tenant under the terms of the Lease, as hereby amended,
at any subsequent time during the Second Expansion Space Term which results in early termination pursuant to the provisions of Section 20 of the Original Lease, then as a part of the recovery set forth in Section 20 of the Original Lease,
Landlord shall be entitled to the then unamortized portion of the Abatement Amount, with such amortization to be calculated on a monthly basis over the period from the May 1, 2014 Second Expansion Commencement Date through the June 30,
2018 Expiration Date. 
 6.     Tenant’s Proportionate Share for the Second Expansion
Space.   Notwithstanding anything to the contrary in the Lease, during the Second Expansion Space Term, Tenant’s Proportionate Share for the Second Expansion Space shall be 1.25%. 

7.     Improvements to the Second Expansion Space.   Commencing upon January 1,
2014, Tenant shall cause certain work to be performed in the Second Expansion Space pursuant to the Tenant Work Letter attached hereto as EXHIBIT B, using Building-standard quantities and materials (the “Improvements”). Tenant
hereby agrees that the construction of the Improvements shall in no way constitute a constructive eviction of Tenant nor entitle Tenant to any abatement of Basic Rental payable pursuant to this Second Amendment. Landlord shall have no responsibility
or for any reason be liable to Tenant for any direct or indirect injury to or interference with Tenant’s business arising from the construction of the Improvements, nor shall Tenant be entitled to any compensation or damages from Landlord for
loss of the use of the whole or any part of the Existing Premises or the Second Expansion Space resulting from the construction of the Improvements or for any inconvenience or annoyance occasioned by the construction of the Improvements. Except as
specifically set forth in this Second Amendment, Tenant hereby agrees to accept the Second Expansion Space in its “as-is” condition and Tenant hereby acknowledges that Landlord shall not be obligated to provide or pay for any improvement
work or services related to the improvement of the Second Expansion Space. Tenant also acknowledges that Landlord has made no representation or warranty regarding the condition of the Second Expansion Space. 

8.     Letter of Credit.   Landlord and Tenant hereby acknowledge that Landlord is
currently holding a Letter of Credit on file in the amount of $[...***...]. Landlord shall continue to hold such Letter of Credit in accordance with the applicable terms and conditions of Section 4 of the Original Lease. 

9.       Parking.   Effective as of the Second Expansion Commencement Date or
commencement of the Beneficial Occupancy Period (if earlier) and continuing throughout the Second Expansion Space Term, Tenant shall rent a total of nine (9) unreserved parking passes (i.e., the seven (7) passes referenced in
Section 9 of the First Amendment, plus the conversion of one (1) current month-to-month pass to a 

  
  

***Confidential Treatment Requested 

  
 2 

 
permanent pass plus one (1) additional pass) for use in the Building’s underground parking facility. Tenant’s rental and use of such parking passes shall continue to be in
accordance with, and subject to, all provisions of Section 23 of the Original Lease, and at the prevailing rate charged from time to time. 

10.     Option to Extend.   Tenant’s existing option rights shall remain in full
force and effect, pursuant to the terms and conditions of Section 31 of the Original Lease; provided however, the Option shall apply to the entirety of the Existing Premises and the Second Expansion Space. 

11.     Monument Sign.   Landlord and Tenant acknowledge that Landlord is currently
constructing a multi-tenant monument sign at the entrance to Corporate 500 Centre. Tenant shall be entitled to install, at Tenant’s sole cost and expense, the following (collectively, “Tenant’s Signage”): (i) a sign adjacent
to the entry to the Second Expansion Space, with the frame of such sign 23” wide by 6” tall, with 1 7⁄8” capital letters and 1 1⁄2” lower case letters, and (ii) a strip on such monument sign. The graphics, materials, color, design and the specifications for Tenant’s Signage
shall be subject to Landlord’s reasonable approval. Tenant’s Signage shall be personal to the Original Tenant or an Affiliated Assignee (as those terms are defined in Article 31 of the Original Lease) and may not be assigned to any other
assignee or sublessee, or any other person or entity. Landlord has the right, but not the obligation, to oversee the installation of Tenant’s Signage. The cost to maintain and operate, if any, Tenant’s Signage shall be paid for by Tenant.
Upon the expiration or earlier termination of the Lease (as amended), Tenant shall be responsible for any and all costs associated with the removal of Tenant’s Signage, including, but not limited to, the cost to repair and restore the monument
to its original condition, normal wear and tear excepted. Notwithstanding anything to the contrary contained herein, if Landlord grants signage rights on such monument to another tenant leasing a larger number of rentable square feet than Tenant,
Landlord may, at Tenant’s expense, remove Tenant’s Signage granted to Tenant under (ii) above from the monument and repair any damage to the monument resulting from such removal. 

12.     Brokers.   Each party represents and warrants to the other that no broker, agent
or finder, other than Steve Kling and Chris Cummins of Colliers International on behalf of Landlord and Joe Learner of Studley on behalf of Tenant (collectively, the “Brokers”), negotiated or was instrumental in negotiating or
consummating this Second Amendment. Each party further agrees to defend, indemnify and hold harmless the other party from and against any claim for commission or finder’s fee by any entity, other than the Brokers, who claims or alleges that
they were retained or engaged by or at the request of such party in connection with this Second Amendment. 

13.     Payments to Landlord.   Notwithstanding anything to the contrary contained in the
Lease, any and all amounts due and payable by Tenant to Landlord shall be in the form of (i) business checks, (ii) wire transfers, (iii) electronic funds transfers, and (iv) automated clearing house payments. Any other forms of
payment are not acceptable to Landlord including, without limitation (1) cash or currency, (2) cashier’s checks and money orders, (3) traveler’s checks, (4) payments from credit unions or other non-bank financial
institutions, (5) multiple payments for one (1) scheduled payment, and (6) third party checks. 

14.     No Further Modification.   Except as set forth in this Second Amendment, all of
the terms and provisions of the Lease shall apply during the Second Expansion Space Term and shall remain unmodified and in full force and effect. Effective as of the date hereof, all references to the “Lease” shall refer to the Lease as
amended by this Second Amendment. 
 (Signatures appear on the following page.) 

  
 3 

 IN WITNESS WHEREOF, this Second Amendment has been executed as of the day and
year first above written. 
  

											
	“LANDLORD”	 		 	LONG RIDGE OFFICE PORTFOLIO, L.P.,
		 		 	a Delaware limited partnership
				
		 		 	By:  	 	M.F. FUNDING, INC.,
		 		 		 	a Delaware corporation
		 		 		 	Its:   General Partner
					
		 		 		 	By:  	 	/s/ Scott E. Lyle
						
		 		 		 		 	Its:  	 	Vice President

  

							
	“TENANT”	 		 	HORIZON PHARMA USA, INC.,
		 		 	a Delaware corporation
				
		 		 	By:	 	/s/ Timothy P. Walbert
				
		 		 	Print Name:	 	Timothy P. Walbert
				
		 		 	Title:	 	Chairman, President & CEO
				
		 		 	By:	 	 
				
		 		 	Print Name:	 	 
				
		 		 	Title:	 	 

  
 4 

 EXHIBIT A – Outline of Second Expansion Space 

 
 

 

  
 Exhibit A-1 

 EXHIBIT B – Tenant Work Letter 

This Tenant Work Letter shall set forth the terms and conditions relating to the renovation of the tenant improvements in the
Second Expansion Space. This Tenant Work Letter is essentially organized chronologically and addresses the issues of the renovation of the Second Expansion Space, in sequence, as such issues will arise. 

1.      LANDLORD’S INITIAL CONSTRUCTION IN THE SECOND EXPANSION SPACE 

Landlord has constructed, at its sole cost and expense, the base, shell and core (i) of the Second Expansion
Space, and (ii) of the floor of the Building on which the Second Expansion Space is located (collectively, the “Base, Shell and Core”). Tenant has inspected and hereby approves the condition of the Second Expansion Space and
Base, Shell and Core, and agrees that, subject to construction of the Improvements, the Second Expansion Space and the Base, Shell and Core shall be delivered to Tenant in its current “as-is” condition. The improvements to be initially
installed in the Second Expansion Space shall be designed and constructed pursuant to this Tenant Work Letter. Any costs of initial design and construction of any improvements to the Second Expansion Space shall be an “Improvement Allowance
Item”, as that term is defined in Section 2B of this Tenant Work Letter. 
 2.      IMPROVEMENTS 

A.     Improvement Allowance.   Beginning January 1, 2014, Tenant shall be entitled
to a one-time improvement allowance (the “Improvement Allowance”) in the amount of $187,920 for the costs relating to the initial design and construction of Tenant’s improvements which are permanently affixed to the Second
Expansion Space (the “Improvements”). In no event shall Landlord be obligated to make disbursements pursuant to this Tenant Work Letter in a total amount which exceeds the Improvement Allowance. 

B.     Improvement Allowance Items.   Except as otherwise set forth in this Tenant Work
Letter, the Improvement Allowance shall be disbursed by Landlord (each of which disbursements shall be made pursuant to Landlord’s disbursement process) for costs related to the construction of the Improvements and for the following items and
costs (collectively, the “Improvement Allowance Items”): (i) payment of the fees of the “Architect” and the “Engineers,” as those terms are defined in Section 3 of this Tenant Work Letter, and payment
of the fees incurred by, and the cost of documents and materials supplied by, Landlord and Landlord’s consultants in connection with the preparation and review of the “Construction Drawings,” as that term is defined in Section 3
of this Tenant Work Letter; (ii) the cost of permits and license fees relating to construction of the Improvements; (iii) the cost of any changes in the Base, Shell and Core required by the Construction Drawings; (iv) the cost of any
changes to the Construction Drawings or Improvements required by applicable building codes (the “Code”); (v) the cost of construction of the Improvements, including, without limitation, testing and inspection costs and trash
removal costs, and contractors’ fees and general conditions; (vi) sales and use taxes; and (vii) all other costs to be expended by Tenant and reasonably approved Landlord in connection with the construction of the Improvements.
However, in no event shall more than three and 50/100 Dollars ($3.50) per rentable square foot of the Improvement Allowance be used for the aggregate cost of items described in (i) and (ii) above; any additional amount incurred as a result
of (i) and (ii) above shall be paid for by Tenant as part of the Over-Allowance Amount. 

C.     Application toward FF&E and/or Rent Credit.   Notwithstanding the foregoing,
Tenant shall have the right to apply up to $83,520.00 of the Improvement Allowance to reimburse Tenant for costs associated with the purchase and/or installation of furniture, fixtures and equipment (“FF&E”) within the Second
Expansion Space and/or as a credit against monthly Basic Rental for the Second Expansion Space; provided, however, Tenant shall be required to provide Landlord with written notice of its election to utilize any portions of the Improvement Allowance
toward any FF&E costs and/or monthly Basic Rental credit, with such notice including copies of paid invoices for furniture, fixtures and equipment in the event Tenant elects to use any portion of the Improvement Allowance for reimbursement of
FF&E costs. In no event shall Tenant be entitled to any credit for any unused portion of the Improvement Allowance not applied (toward Improvements, FF&E and/or monthly Basic Rental credit) by December 31, 2014. 

D.     Disbursement of the Improvement Allowance.   Landlord shall disburse the
Improvement Allowance in interim progress disbursements (“Progress Disbursement”), and one (1) final disbursement (“Final Disbursement”), within thirty (30) days after Tenant submits complete written
disbursement requests, as further described below. Landlord may issue checks to fund the Improvement Allowance jointly or separately to Tenant, its general contractor, and any other of “Tenant’s Agents” (as defined in Section 4A
below). Without limiting the generality of the provisions below, Landlord may withhold payments of the Improvement Allowance pending inspection of the Improvements theretofore performed to determine that the applicable portions of the Improvements
were properly performed in accordance with this Tenant Work Letter and the Approved Working Drawings, and that no substandard work exists 

  
 Exhibit B-1 

 
which adversely affects the mechanical, electrical, plumbing, heating, ventilating and air conditioning, life-safety or other systems of the Building, the curtain wall of the Building, the
structure or exterior appearance of the Building, or any other tenant’s use of such other tenant’s leased premises in the Building; provided, such inspections shall not be deemed a warranty by Landlord that such conditions do not exist nor
a waiver of Landlord’s rights if such conditions exist and were not reported during such inspection. 
  

	 	(a)	 Progress Disbursements.   Each Progress Disbursement shall be paid based on the percentage value of the Improvements theretofore
completed (“Completed Work Percentage”), less ten percent (10%) retention (“Retention”) to be deferred to the Final Disbursement. Tenant shall not request any Progress Payments more often than monthly. In each
Progress Disbursement Request, Tenant shall: (i) state the Completed Work Percentage as of the date of such Progress Disbursement Request (which may include any material actually delivered to the Second Expansion Space as of such date), and
show the subtraction of the Retention required herein, (ii) set forth the total estimated cost of the Improvements, and the computation of the Progress Disbursement, (iii) attach a general contractor application for payment on AIA G702 and
G703 forms (or such modified version and/or a “sworn statement” or “affidavit of payment” in such form as Landlord may require consistent with Illinois laws and customs to protect against mechanics’ and other liens),
respecting the portion of the Improvements covered by such Progress Disbursement Request, duly executed and certified under oath (or sworn under penalty of perjury and notarized as Landlord may require consistent with Illinois laws) by the general
contractor and all subcontractors, and which shall include execution and certification by the Architect that all Improvements for which payment is requested have been properly completed in accordance with the Approved Working Drawings, and shall
show the names of all parties furnishing material and labor and the amount previously paid and due or to become due to each of them, and shall include invoices and other reasonable supporting documentation, and (iv) include partial lien
releases (which may, at Landlord’s sole option, be conditional as to the amount of the current payment requested, but shall in any event be unconditional releases as to prior amounts), by the general contractor and all subcontractors,
suppliers, materialmen and persons who have provided any labor, services, material, fixtures, apparatus or machinery (collectively, “Subcontractors”), in such form as Landlord may require consistent with Illinois laws, respecting
the portion of the Improvements covered by such Progress Disbursement Request. 

  

	 	(b)	 Final Disbursement Request.   Tenant’s Final Disbursement Request shall specify that it is the “Final Disbursement
Request,” and shall include: (i) an “Architect’s Certificate of Substantial Completion” on the current AIA form, and an Architect’s certificate for final payment, (ii) a general contractor application for payment
on AIA G702 and G703 forms (or such modified version and/or such form of “sworn statement” or “affidavit of payment” as Landlord may require consistent with Illinois laws to protect against mechanics’ and other liens),
duly executed and certified under oath (or sworn under penalty of perjury and notarized as Landlord may require consistent with Illinois laws) by the contractor and all Subcontractors, and which shall include execution and certification by the
Architect, as further described above respecting Progress Disbursement Requests, (iii) copies of all invoices for the Improvements not previously provided, (iv) a copy of the permanent certificate of occupancy for the Second Expansion
Space (if required by law, or otherwise such evidence or government inspections and approvals as may be customary), and (v) final, complete, unconditional lien releases by the general contractor and all Subcontractors in such form as Landlord
may require consistent with Illinois laws, and (vi) such other evidence as Landlord may reasonably require that the costs of the Improvements have been paid and that no architect’s, engineer’s mechanic’s, materialmen’s or
other liens have been or may be filed against the Building or Second Expansion Space arising out of the design or performance of such Improvements. Notwithstanding anything to the contrary contained herein, to the extent substantial completion has
occurred, but any so-called punch-list items or other items remain to be performed, Landlord may defer paying the Final Disbursement or such portion thereof as Landlord may determine, until all such items are fully completed. 

 

	 	(c)	 Other Terms.   Landlord shall only be obligated to make disbursements from the Improvement Allowance to the extent costs are
incurred by Tenant for Improvement Allowance Items. Except for furniture, fixtures and equipment purchased under Section 2.C above, all Improvement Allowance Items for which the Improvement Allowance has been made available shall be deemed
Landlord’s property under the terms of this Second Amendment. 

  
 Exhibit B-2 

 3.      CONSTRUCTION DRAWINGS 

A.     Selection of Architect/Construction Drawings.   Tenant shall retain an
architect/space planner approved by Landlord (the “Architect’’) to prepare the “Construction Drawings,” as that term is defined in this Section 3. Tenant shall also retain the engineering consultants approved by
Landlord (the “Engineers”) to prepare all plans and engineering working drawings relating to the structural, mechanical, electrical, plumbing, HVAC and life safety work of the Improvements. The Architect and the Engineers are
collectively referred to herein as the “Design Professionals”. The plans and drawings to be prepared by Architect and the Engineers hereunder shall be known collectively as the “Construction Drawings.” All
Construction Drawings shall comply with the drawing format and specifications as reasonably determined by Landlord, and shall be subject to Landlord’s reasonable approval. Tenant and Architect shall verify, in the field, the dimensions and
conditions as shown on the relevant portions of the base building plans, and Tenant and Architect shall be solely responsible for the same, and Landlord shall have no responsibility in connection therewith. Landlord’s review of the Construction
Drawings as set forth in this Section 3, shall be for its sole purpose and shall not imply Landlord’s review of the same, or obligate Landlord to review the same, for quality, design, Code compliance or other like matters. Accordingly,
notwithstanding that any Construction Drawings are reviewed by Landlord or its space planner, architect, engineers and consultants, and notwithstanding any advice or assistance which may be rendered to Tenant by Landlord or Landlord’s space
planner, architect, engineers, and consultants, Landlord shall have no liability whatsoever in connection therewith and shall not be responsible for any omissions or errors contained in the Construction Drawings. Approval of the Construction
Drawings by Landlord is not a representation that the drawings are in compliance with the requirements of governing authorities, and it shall be Tenant’s responsibility to meet and comply with all federal, state, and local code requirements.
Landlord’s approval of the “Contract” (as defined in Section 4B(a) below), and Landlord’s designations, lists, recommendations or approvals concerning Design Professionals and Tenant’s Agents, shall not be deemed a
warranty as to the quality or adequacy thereof or of the Construction Drawings or the Improvements, or the design thereof, or of compliance with laws, codes and other legal requirements. 

B.     Approved Working Drawings.   Landlord shall approve (or disapprove) working
drawings prepared by the Architect within ten (10) days after Landlord receives the final working drawings (the “Approved Working Drawings”). Tenant shall submit the same to the applicable governmental agencies and diligently
pursue its receipt of all applicable building permits. Tenant hereby agrees that neither Landlord nor Landlord’s consultants shall be responsible for obtaining any building permit or certificate of occupancy for the Second Expansion Space and
that obtaining the same shall be Tenant’s responsibility; provided, however, that Landlord shall cooperate with Tenant in executing permit applications and performing other ministerial acts reasonably necessary to enable Tenant to obtain any
such permit or certificate of occupancy. No changes, modifications or alterations in the Approved Working Drawings may be made without the prior written consent of Landlord, which consent may not be unreasonably withheld. 

4.      CONSTRUCTION OF THE IMPROVEMENTS 

A.     Contractor and Tenant’s Agents.   The contractor which shall construct the
Improvements shall be retained by and contract directly with Tenant and shall be a contractor reasonably approved by Landlord. The contractor selected may be referred to herein as the “Contractor”. All subcontractors, laborers,
materialmen, and suppliers used by Tenant (such subcontractors, laborers, materialmen, and suppliers, and the Contractor to be known collectively as “Tenant’s Agents”) must be approved in writing by Landlord, which approval
shall not be unreasonably withheld or delayed. If Landlord does not approve any of Tenant’s proposed subcontractors, laborers, materialmen or suppliers, Tenant shall submit other proposed subcontractors, laborers, materialmen or suppliers for
Landlord’s written approval. 
 B.     Construction of Improvements by Tenant’s Agency.

  

	 	(a)	 Construction Contract; Cost Budget.   Prior to Tenant’s execution of the construction contract and general conditions with
Contractor (the “Contract”), Tenant shall submit the Contract to Landlord for its approval with regard to proper insurance and licensing requirements and any other provisions which may adversely affect Landlord or Landlord’s
interest in the Building, and which approval shall not be unreasonably withheld or delayed by more than five (5) business days after Landlord’s receipt of the Contract. Prior to the commencement of the construction of the Improvements, and
after Tenant has accepted all bids for the Improvements, Tenant shall provide Landlord with a detailed breakdown, by trade, of the final costs to be incurred or which have been incurred in connection with the design and construction of the
Improvements to be performed by or at the direction of Tenant or the Contractor, which costs form a basis for the amount of the Contract (the “Final Costs”). Prior to the commencement of construction of the Improvements, Tenant
shall supply Landlord with an amount (the “Over-Allowance Amount”) equal to the difference between the amount of the Final Costs and the amount of the Improvement Allowance (less any portion thereof already disbursed by Landlord, or
in the process of being disbursed by Landlord, 

  
 Exhibit B-3 

	 	 
on or before the commencement of construction of the Improvements). The Over-Allowance Amount shall be disbursed by Landlord prior to the disbursement of any of the then remaining portion of the
Improvement Allowance, and such disbursement shall be pursuant to the same procedure as the Improvement Allowance. In the event that, after the Final Costs have been delivered by Tenant to Landlord, the costs relating to the design and construction
of the Improvements shall change, any additional costs necessary to such design and construction in excess of the Final Costs, shall be paid by Tenant to Landlord immediately as an addition to the Over-Allowance Amount or at Landlord’s option,
Tenant shall make payments for such additional costs out of its own funds, but Tenant shall continue to provide Landlord with the documents described in Section 2D(a) (i), (ii), (iii) and (iv) of this Tenant Work Letter, above, for
Landlord’s approval, prior to Tenant paying such costs. 

  

	 	(b)	 Tenant’s Agents. 

  

	 	(i)	 Landlord’s General Conditions for Tenant’s Agents and Tenant Improvement Work.   Tenant’s and Tenant’s
Agent’s construction of the Improvements shall comply with the following: (i) the Improvements shall be constructed in strict accordance with the Approved Working Drawings; (ii) Tenant’s Agents shall submit schedules of all work
relating to the Improvements to Contractor and Contractor shall, within five (5) business days of receipt thereof, inform Tenant’s Agents of any changes which are necessary thereto, and Tenant’s Agents shall adhere to such corrected
schedule; and (iii) Tenant shall abide by all rules made by Landlord’s Project manager with respect to the use of freight, loading dock and service elevators, storage of materials, coordination of work with the contractors of other
tenants, and any other matter in connection with this Tenant Work Letter, including, without limitation, the construction of the Improvements. 

  

	 	(ii)	 Indemnity and Waiver.   Tenant’s indemnity of Landlord and waiver of claims against Landlord as set forth in the Lease shall
also apply, to the extent not prohibited by applicable Illinois laws, with respect to any and all costs, losses, damages, injuries and liabilities related in any way to any act or omission of Tenant or Tenant’s Agents, or anyone directly or
indirectly employed by any of them, or in connection with Tenant’s non-payment of any amount arising out of the Improvements and/or Tenant’s disapproval of all or any portion of any request for payment. Such indemnity by Tenant, as set
forth in the Lease, shall also apply, to the extent not prohibited by applicable Illinois laws, with respect to any and all costs, losses, damages, injuries and liabilities related in any way to Landlord’s performance of any ministerial acts
reasonably necessary (i) to permit Tenant to complete the Improvements, and (ii) to enable Tenant to obtain any building permit or certificate of occupancy for the Second Expansion Space. 

 

	 	(iii)	 Requirements of Tenant’s Agents.   Each of Tenant’s Agents shall guarantee to Tenant and for the benefit of Landlord
that the portion of the Improvements for which it is responsible shall be free from any defects in workmanship and materials for a period of not less than one (1) year from the date of completion thereof. Each of Tenant’s Agents shall be
responsible for the replacement or repair, without additional charge, of all work done or furnished in accordance with its contract that shall become defective within one (1) year after the later to occur of (i) completion of the work
performed by such contractor or subcontractors and (ii) the Second Expansion Commencement Date. The correction of such work shall include, without additional charge, all additional expenses and damages incurred in connection with such removal
or replacement of all or any part of the Improvements, and/or the Building and/or common areas that may be damaged or disturbed thereby. All such warranties or guarantees as to materials or workmanship of or with respect to the Improvements shall be
contained in the Contract or subcontract and shall be written such that such guarantees or warranties shall inure to the benefit of both Landlord and Tenant, as their respective interests may appear, and can be directly enforced by either. Tenant
covenants to give to Landlord any assignment or other assurances which may be necessary to effect such right of direct enforcement. 

  
 Exhibit B-4 

	 	(1)	 Lien-Free Basis.   Tenant’s Contractor and the other Tenant’s Agents and the Design Professionals shall perform all work
and services on a lien-free basis. If a lien is filed or recorded against the Building due to, or in any way associated with, the design, engineering or construction of the Improvements, Tenant agrees to have such lien released of record by
recording a lien release bond or otherwise (in a manner and form approved by Landlord) within five (5) days of Landlord’s notice to Tenant regarding same. If Tenant fails to cause the release of such lien within such five (5) day
period to Landlord’s satisfaction, Landlord may cause the removal of such lien from Landlord’s title or require a deposit by Tenant as provided under Article 10 (Liens) of the Lease, and Tenant agrees to repay Landlord for all costs and
expenses incurred by Landlord to release the lien (including, but not limited to, the payment of the amount stated in the lien, any filing, processing, recording and attorneys’ fees) within ten (10) days of Landlord’s request
therefor, and such amount shall be considered Additional Rent due under the Lease. If Tenant fails to pay Landlord as aforesaid, such failure shall be deemed an uncured noticed material default under the Lease, and Landlord may pursue any remedy
provided for under the Lease, at law or in equity. Under no circumstances shall Landlord’s approval or payment of a Progress Disbursement, Final Disbursement or any other amount, be deemed a waiver of Tenant’s obligations or
Landlord’s rights respecting liens. 

  

	 	(iv)	 Insurance Requirements. 

  

	 	(1)	 General Coverages.   All of Tenant’s Agents shall carry worker’s compensation insurance covering all of their respective
employees, and shall also carry commercial general liability insurance, including property damage, all with limits, in form and with companies as are required to be carried by Tenant as set forth in the Lease. 

 

	 	(2)	 Special Coverages. Tenant shall carry “Builder’s All Risk” insurance in an amount approved by Landlord covering the
construction of the Improvements, and such other insurance as Landlord may require, it being understood and agreed that the Improvements shall be insured by Tenant pursuant to the Lease, as amended by this Second Amendment, during construction and
immediately upon completion thereof. Such insurance shall be in amounts and shall include such extended coverage endorsements as may be reasonably required by Landlord including, but not limited to, the requirement that all of Tenant’s Agents
shall carry excess liability and Products and Completed Operating Coverage insurance, each in amounts not less than $500,000 for each incident, $1,000,000 in aggregate, and in form and with companies as are required to be carried by Tenant as set
forth in the Lease. 

  

	 	(c)	 General Terms.   Certificates for all insurance carried pursuant to this Section 4B(c) shall be delivered to Landlord before
the commencement of construction of the Improvements and before the Contractor’s equipment is moved onto the site. All such policies of insurance must contain a provision that the company writing said policy will give Landlord thirty
(30) days prior written notice of any cancellation or lapse of the effective date or any reduction in the amounts of such insurance. In the event that the Improvements are damaged by any cause during the course of the construction thereof,
Tenant shall immediately repair the same at Tenant’s sole cost and expense. Tenant’s Agents shall maintain all of the foregoing insurance coverage in force until the Improvements are fully completed and accepted by Landlord, except for any
Products and Completed Operation Coverage insurance required by Landlord, which is to be maintained for ten (10) years following completion of the work and acceptance by Landlord and Tenant. All policies carried under this Section 4B(c)
shall insure Landlord and Tenant, as their interests may appear, as well as Contractor and Tenant’s Agents. All insurance maintained by Tenant’s Agents shall preclude subrogation or contribution claims by the insurer against anyone insured
thereunder, to the extent not prohibited under applicable Illinois laws. Such insurance shall provide that it is primary insurance as respects 

  
 Exhibit B-5 

	 	 
the Landlord and that any other insurance maintained by Landlord is excess and noncontributing with the insurance required hereunder. The requirements for the foregoing insurance shall not
derogate from the provisions for indemnification of Landlord by Tenant under Section 4B(b)(ii) of this Tenant Work Letter. 

  

	 	(d)	 Governmental Compliance.   The Improvements shall comply in all respects with the following: (i) the Code and other state,
federal, city or quasi-governmental laws, codes, ordinances and regulations, as each may apply according to the rulings of the controlling public official, agent or other person; (ii) applicable standards of the American Insurance Association
(formerly, the National Board of Fire Underwriters) and the National Electrical Code; and (iii) material and equipment manufacturer’s specifications for the Building and for materials and equipment to be installed as part of the
Improvements. 

  

	 	(e)	 Inspection by Landlord.   Landlord shall have the right to inspect the Improvements at all times, provided however, that
Landlord’s failure to inspect the Improvements shall in no event constitute a waiver of any of Landlord’s rights hereunder nor shall Landlord’s inspection of the Improvements constitute Landlord’s approval of the same. Should
Landlord disapprove any portion of the Improvements, Landlord shall notify Tenant in writing of such disapproval and shall specify the items disapproved. Any defects or deviations in, and/or disapproval by Landlord of, the Improvements shall be
rectified by Tenant at no expense to Landlord, provided however, that in the event Landlord determines that a defect or deviation exists or disapproves of any matter in connection with any portion of the Improvements and such defect, deviation or
matter might adversely affect the mechanical, electrical, plumbing, heating, ventilating and air conditioning or life-safety systems of the Building, the structure or exterior appearance of the Building or any other tenant’s use of such other
tenant’s leased premises, Landlord may take such action as Landlord deems necessary, at Tenant’s expense and without incurring any liability on Landlord’s part, to correct any such defect, deviation and/or matter, including, without
limitation, causing the cessation of performance of the construction of the Improvements until such time as the defect, deviation and/or matter is corrected to Landlord’s satisfaction. 

 

	 	(f)	 Meetings.   Commencing upon the execution of this Second Amendment, Tenant and Landlord shall hold meetings as required at a
reasonable time with the Architect and the Contractor regarding the progress of the preparation of Construction Drawings and the construction of the Improvements, which meetings shall be held at a location designated by Landlord, and Landlord and/or
its agents shall receive prior notice of, and shall have the right to attend, all such meetings, and, upon Landlord’s request, certain of Tenant’s Agents shall attend such meetings. One such meeting each month shall include the review of
Contractor’s current request for payment. 

 C.     Copy of “As
Built” Plans.   At the conclusion of construction, (i) Tenant shall cause the Architect and Contractor (A) to update the Approved Working Drawings as necessary to reflect all changes made to the Approved Working Drawings
during the course of construction, (B) to certify to the best of their knowledge that the “record-set” of as-built drawings are true and correct, which certification shall survive the expiration or termination of the Lease, and
(C) to deliver to Landlord two (2) sets of copies of such as-built drawings within ninety (90) days following substantial completion of the Improvements, and (ii) Tenant shall deliver to Landlord a copy of all warranties,
guaranties, and operating manuals and information relating to the improvements, equipment, and systems in the Second Expansion Space. 

5.      MISCELLANEOUS 

A.     Tenant’s Representative.   Tenant has designated Rob Metz as its sole
representative with respect to the matters set forth in this Tenant Work Letter, who, until further notice to Landlord, shall have full authority and responsibility to act on behalf of the Tenant as required in this Tenant Work Letter. 

B.     Landlord’s Representative.   Prior to commencement of construction of
Improvements, Landlord shall designate a representative with respect to the matters set forth in this Tenant Work Letter, who, until further notice to Tenant, shall have full authority and responsibility to act on behalf of the Landlord as required
in this Tenant Work Letter. 
 C.     Time of the Essence.   Time is of the essence
with respect to Tenant’s obligations under this Tenant Work Letter. Unless otherwise indicated, all references herein to a “number of days” shall mean and refer to calendar days. 

D.     Tenant’s Lease Default.   Notwithstanding any provision to the contrary
contained in the Lease, if an event of default as described in the Lease or this Tenant Work Letter has occurred at any time, 

  
 Exhibit B-6 

 
then (i) in addition to all other rights and remedies granted to Landlord pursuant to the Lease, Landlord shall have the right to withhold payment of all or any portion of the Improvement
Allowance and/or Landlord may cause Contractor to cease the construction of the Second Expansion Space (in which case, Tenant shall be responsible for any delay in the substantial completion of the Second Expansion Space caused by such work
stoppage), and (ii) all other obligations of Landlord under the terms of this Tenant Work Letter shall be forgiven until such time as such default is cured pursuant to the terms of the Lease (in which case, Tenant shall be responsible for any
delay in the substantial completion of the Second Expansion Space caused by such inaction by Landlord). 

E.     Construction Defects.   Landlord shall have no responsibility for the Improvements
and Tenant will remedy, at Tenant’s own expense, and be responsible for any and all defects in the Improvements that may appear during or after the completion thereof whether the same shall affect the Improvements in particular or any parts of
the Second Expansion Space in general. Tenant shall indemnify, defend, hold harmless and reimburse Landlord for any liabilities, costs or expenses incurred by Landlord by reason of any defect in any portion of the Improvements constructed by Tenant
or Tenant’s contractor or subcontractors, or by reason of inadequate cleanup following completion of the Improvements. 

F.     Coordination of Labor.   All of Tenant’s contractors, subcontractors,
employees, servants and agents must work in harmony with and shall not interfere with any labor employed by Landlord, or Landlord’s contractors or by any other tenant or its contractors with respect to any portion of the Building. 

G.     HVAC Systems.   Tenant agrees to be entirely responsible for the maintenance or
the balancing of any heating, ventilating or air conditioning system installed by Tenant and/or maintenance of the electrical or plumbing work installed by Tenant and/or for maintenance of lighting fixtures, partitions, doors, hardware or any other
installations made by Tenant. 

  
 Exhibit B-7EX-10.39

 Exhibit 10.39 

***Text Omitted and Filed Separately with the Securities and Exchange Commission. 

Confidential Treatment Requested Under 

17 C.F.R. Sections 200.80(b)(4) and 240.24b-2 

EXCLUSIVE DISTRIBUTION AGREEMENT – AMENDMENT No. 2 

THIS AGREEMENT is made the 25th day of October 2013 (the “Effective Date”) 

BETWEEN: 
  

	(1)	 HORIZON PHARMA AG a company incorporated in accordance with the laws of Switzerland with its registered office
at Kägenstrasse 17, CH-4153 Reinach, Switzerland (the “Principal”); and 

  

	(2)	 MUNDIPHARMA INTERNATIONAL CORPORATION LIMITED a company
incorporated in accordance with the laws of Bermuda with its registered office at Canon’s Court, 22 Victoria Street, Hamilton, HM 12 Bermuda (the “Distributor”). 

RECITALS: 
  

	 	(A)	 WHEREAS, the Principal and Distributor concluded an Exclusive Distribution Agreement (“EDA”) on November 4, 2010 to have the Product
registered, marketed, sold and distributed by the Distributor in the Field in the Territory (the terms Product, Field and Territory are defined in the EDA); and, 

 

	 	(B)	 WHEREAS, the Parties amended the EDA, effective March 5, 2012; and 

 

	 	(C)	 WHEREAS, the Parties wish to further amend the EDA to include additional territories; and 

 

	 	(D)	 WHEREAS, the Principal has agreed to grant the Distributor an Exclusive licenses and the rights as set out and upon and subject to the terms and
conditions in this agreement and the EDA. 

 IT IS AGREED as follows: 

 

	1.	 DEFINITIONS AND INTERPRETATION 

	1.1	 As used in this Agreement, capitalized words and expressions shall have the meanings defined in the EDA including this AMENDMENT, provided that the
following words and phrases shall have the following meanings: In this Agreement, the following terms shall have the following meanings: 

  

	 “AMENDMENT” 
	 means this Agreement between the Parties as set out and described herein. 

  

	 “COMMENCEMENT DATE” 
	 means (1) November 4, 2010 with respect to the following countries in the Territory: Australia, China, Hong Kong, Indonesia, Korea, Malaysia, New Zealand,
Philippines, Singapore, South Africa, Taiwan, Thailand, and Vietnam; and (2) March 5, 2012 with respect to the following countries in the Territory: Mexico, Brazil, Argentina, Colombia, Venezuela, Peru, Chile, Ecuador, Dominican Republic,
Guatemala, Costa Rica, Uruguay, Bolivia, Panama, Nicaragua, El Salvador and Honduras; and (3) the Effective Date of this AMENDMENT for: Algeria, Angola, Bahrain, Benin, Botswana, Burkina Faso, Burundi, Cameroon, Central African Republic, Congo,
Cote D’Ivoire, Democratic Republic of the Congo, Djibouti, Egypt, Equitorial Guinia, Eritria, Ethiopia, Gabon, Ghana, Guinia, Iran, Iraq, , Jordan, Kenya, Kuwait, Lebanon, Lesotho, Libya, Madagascar, Malawi, Mali, Mauritius, Morocco,
Mozambique, Namibia, Nigeria, Oman, Qatar, Rwanda, Saudi Arabia, Senegal, Seychelles, Sierra Leone, Somalia, , South Sudan, Sudan, Swaziland, Tanzania, Togo, Tunisia, U.A.E, Uganda, Yemen, Zambia, Zimbabwe. 

 

	1.2	 Any reference in this AMENDMENT to “writing” or cognate expressions includes a reference to facsimile transmission.

  

	1.3	 The headings in this AMENDMENT are for convenience only and shall not affect its interpretation. 

 

	1.4	 References to “persons” includes individuals, bodies corporate (wherever incorporated), unincorporated associations and partnerships.

	1.5	 Any reference to an enactment or statutory provision is a reference to it as it may have been, or may from time to time be amended, modified,
consolidated or re-enacted. 

  

	2.	 AMENDMENTS TO THE EDA 

  

	2.1	 Section 2.3.1 is added as follows: 

For all countries in the Territory with a Commencement Date that is the Effective Date of this AMENDMENT, Distributor shall,
prior to selling, marketing, distributing or otherwise making available or offering Product for sale in such country, obtain, at its sole cost, the Trademark, or if the Trademark is for any reason not available in such country any other trademark of
its choice provided that such Trademark is acceptable to the Principal and provided further that the Trademark will upon Principal’s written request, be transferred to the Principal subject to the Principal’s obligation to reimburse the
Distributor for all reasonably incurred direct and indirect costs. 
  

	2.2	 Section 4.8 of the Agreement shall be amended as follows: 

The Principal shall (and shall use commercially reasonable efforts to exercise any rights available to the Principal under the
Development and License Agreement to require that SkyePharma pic shall), at the Principal’s cost and expense, maintain the Principal Intellectual Property in the Territory which shall include (without limitation) the prosecution, filing,
maintenance and renewal of any patents and any reissues or reexaminations of any patents, including the payment of all related fees, with respect to any country in the Territory with a Commencement Date of November 4, 2010. 

Before the Commencement Date, the Principal shall have provided the Distributor with a reasonably detailed written report of
all material matters concerning the maintenance of the Principal Intellectual Property in the Territory. After the Commencement Date, upon written request by the Distributor (but not more often than on a quarterly basis), the Principal shall provide
the Distributor with reasonably detailed written reports on material matters concerning the maintenance of the Principal Intellectual Property in the Territory. The Principal shall (and shall use commercially reasonable efforts to exercise any
rights available to the Principal under the Development and License Agreement to require that SkyePharma plc shall) promptly sign all documents and take all other actions as may be necessary or desirable to maintain the Principal Intellectual
Property in the Territory. If the Principal decides to cease the prosecution or maintenance of any Principal Intellectual Property in the Territory, then subject to the Development and License Agreement, it shall notify the Distributor in writing
sufficiently in advance so that the Distributor may, at its discretion, assume the responsibility for the prosecution or maintenance of such Principal Intellectual Property, at the Distributor’s sole expense. 

 

	2.3	 Section 5.2.1 is added as follows: 

The terms described in Section 5.2 will not apply to any of countries in the Territory with a Commencement Date that is
the Effective Date of this AMENDMENT. 

	2.4	 Section 5.22 is added as follows: 

Distributor is in compliance, and shall at all times maintain compliance, with all applicable laws and regulations in
performing its obligations, including all consumer protection, health, safety, environmental, customs, import/export and all other applicable foreign, federal, state and local laws, regulations, standards and requirements. Distributor will
specifically comply with the all applicable anti-corruption laws, including the U.S. Foreign Corrupt Practices Act. Distributor promises that the Products (including any related technical data) will not be exported, sold, or otherwise diverted
outside the Territory. Distributor agrees to comply with all applicable import, export, customs, licensing and product registration requirements, including the applicable requirements for a “routed export transaction” and certifies that
(a) its export privileges have not been suspended, revoked or denied by the U.S. Bureau of Export Administration; (b) the Products are intended for civilian use; (c) the Products will not be involved in any way with the manufacture or
distribution of weapons; (d) no technical data received from Principal will be transferred to any other party without Principal’s prior written consent. Buyer acknowledges U.S. origin items are subject to U.S. Export Administration
Regulations. Distributor further represents that it has all necessary licenses or other approvals required to use, possess, prescribe or otherwise distribute the Products as permitted in this Agreement. 

 

	2.5	 Schedule 1 of the EDA is amended to add the following additional countries: 

“Algeria, Angola, Bahrain, Benin, Botswana, Burkina Faso, Burundi, Cameroon, Central African Republic, Congo, Cote
D’Ivoire, Democratic Republic of the Congo, Djibouti, Egypt, Equitorial Guinia, Eritria, Ethiopia, Gabon, Ghana, Guinia, Iran, Iraq, Jordan, Kenya, Kuwait, Lebanon, Lesotho, Libya, Madagascar, Malawi, Mali, Mauritius, Morocco, Mozambique,
Namibia, Nigeria, Oman, Qatar, Rwanda, Saudi Arabia, Senegal, Seychelles, Sierra Leone, Somalia,South Sudan, Sudan, Swaziland, Tanzania, Togo, Tunisia, U.A.E, Uganda, Yemen, Zambia, Zimbabwe.” 

 

	2.6	 Schedule 3 of the EDA is amended to add the following Milestone Payments: 

 

					
	 	 
	“Milestone Event	  	Milestone Payment	 
	 	 
	 Amount to be paid within five
(5) business days of the signature of this AMENDMENT
	  	 	[...***...]	  

  
  

***Confidential Treatment Requested 

 In WITNESS WHEREOF the PARTIES hereto have caused this AMENDMENT to be executed in
duplicate by their duly authorised officers as of the Commencement Date. 
  

													
	HORIZON PHARMA AG	 	 	 	 	 	MUNDIPHARMA INTERNATIONAL CORPORATION LIMITED
	 				 		 
	By:	 	/s/ Robert W. Metz	 		 		 	By:	 	/s/ Douglas Docherty	 	 
	Name:	 	Robert W. Metz	 		 		 	Name:	 	Douglas Docherty	 	 
	Title:	 	SVP Business Ops	 		 		 	Title:	 	General Manager	 	 
	 	 	 	 	 	 	 	 	 	 	 	 	 

 S:/8613a 
  

					
	HORIZON PHARMA AG	 	 
	 		 
	By:	 	/s/ Timothy P. Walbert	 	 
	Name:	 	Timothy P. Walbert	 	 
	Title:	 	Chairman, President and CEO

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