Document:

Filed by Automated Filing Services Inc. (604) 609-0244 - Icon Development, Inc. - Exhibit  10.1

PLEDGE AGREEMENT

     This pledge agreement (this
“Agreement”), dated as of April 24, 2007, by and among Ken Swaisland, a resident
of British Columbia, Canada (“Mr. Swaisland”), Elliot Lebowitz, a resident of
Massachusetts (“Mr. Lebowitz,” together with Mr. Swaisland, the “Pledgors”),
Icon Development, Inc., a Nevada corporation (“ICON”) and American Xeno, Inc., a
Nevada corporation (“XENO”).

     WHEREAS, ICON has provided
to XENO, and XENO has received to date from ICON, an aggregate of US$325,000 in
cash in the form of refundable advances, and may receive additional advances as
may be agreed by the parties hereto, to XENO (the “Advances”) prior to the
closing of the proposed merger (the “Merger”) of Icon Acquisition Corporation, a
Delware corporation and a wholly-owned subsidiary of ICON (“MERGER SUB”), with
and into XENO pursuant to an agreement and plan of merger dated as of April 24,
2007, among ICON, XENO, MERGER SUB and the stockholders of XENO (the “Agreement
and Plan of Merger”); and

     WHEREAS, as a term of the
Agreement and Plan of Merger, ICON has required that the Pledgors, who are both
significant stockholders of XENO, grant to ICON, and the Pledgors have agreed to
grant to ICON, a security interest in all of the shares of common stock owned by
the Pledgors in XENO (the “Pledged Shares”) as security for the repayment by
XENO of the Advances should the Merger not be consummated pursuant to the terms
and conditions of Agreement and Plan of Merger.

     NOW, THEREFORE, in
consideration of the premises, the mutual agreements set forth herein and other
good and valuable consideration, the receipt and adequacy of which are hereby
acknowledged, the parties agree as follows:

1. Pledge of Stock.

     (a) Pledge. As security
for the prompt repayment of the Advances to XENO from ICON pursuant to the
Agreement and Plan of Merger, the Pledgors hereby grant a security interest to
ICON in the Pledged Shares.

     (b) Delivery. Immediately
upon execution of this Agreement, Pledgors will deliver to ICON the certificates
representing all of the Pledged Shares, which certificates shall be endorsed in
blank or with executed stock powers attached.

2. Rights and Benefits of Pledged Shares.

     (a) General. Except as
provided in Section 2(b), ICON shall receive and hold (by ICON or by an agent of
ICON) the Pledged Shares and any property (including without limitation monies
or securities) distributed or issued with respect to the Pledged Shares, whether
as a dividend, in partial or complete liquidation, pursuant to a merger or
reorganization plan or otherwise. The Pledgors shall cause any property
distributed or issued with respect to the Pledged Shares to be assigned and
transferred to ICON and delivered to ICON, and such securities shall be subject
to the terms and conditions of this Agreement.

     (b) Voting. Unless and
until a default is declared by ICON pursuant to Section 4, the Pledgors shall be
entitled to vote the Pledged Shares.

     (c) Assignment, Etc.
Except as provided or specifically permitted herein, the Pledgors shall not
pledge, sell, assign, transfer or otherwise dispose of the Pledged Shares
without the prior written approval of ICON.

3. Appointment of ICON as Attorney-in-Fact.

     The Pledgors hereby appoint and
constitute ICON as the Pledgors’ true and lawful attorney-in-fact and with full
power of substitution in the premises to execute such assignments and/or
endorsements of the Pledged Shares as may be necessary to effect the rights and
remedies which ICON has under this Agreement in the event of a default under
this Agreement.

4. Event of Default; Remedies.

     The failure to repay the Advances
by XENO to ICON within fifteen (15) days of the date that the Agreement and Plan
of Merger is terminated by Icon in accordance with Section 9.1(b) or the
transaction contemplated by the Agreement and Plan of Merger is not consummated
as a result of any action on the part of Xeno shall constitute an event of
default under this Agreement.

     Upon the occurrence of an event
of default, ICON shall have the option to declare this Agreement in default and
thereupon ICON is authorized to exercise and shall have, in addition to the
rights and remedies provided in this Agreement and all other applicable rights
and remedies, the rights and remedies of a secured party under the Uniform
Commercial Code of the State of Nevada and any other applicable laws. In
particular, and without limitation, ICON is authorized at its option and without
further notice or demand to cause the Pledged Shares to be transferred of record
to ICON or its agent or nominee and shall be entitled to exercise all rights of
ownership in respect to the Pledged Shares and all property received with
respect to the Pledged Shares.

5. Release of Collateral.

     At such time as the Merger has
been consummated pursuant to the terms and conditions of the Agreement and Plan
of Merger, ICON shall deliver the Pledged Shares and any property distributed
with respect to the Pledged Shares to the Pledgors, and the Pledgors’ shall
thereafter be discharged in full from any and all obligations under this
Agreement.

6. Cooperation.

     Upon the execution of this
Agreement and at any time or from time to time thereafter, the parties hereto
agree to cooperate in carrying out the terms of this Agreement, including the
execution and delivery of such further instruments and documents as may be
reasonably requested in order to more effectively carry out the terms and
conditions of this Agreement.

7. Miscellaneous.

     (a) Entire Agreement. This
Agreement and the Agreement and Plan of Merger contain the entire understanding
between the parties hereto with respect to the subject matter hereof and thereof
and supersedes any prior understandings, agreements or representations, written
or oral, relating to the subject matter hereof and thereof.

     (b) Counterparts. This
Agreement may be executed in separate counterparts, each of which will be an
original and all of which taken together shall constitute one and the same
agreement, and any party hereto may execute this Agreement by signing any such
counterpart.

2

     (c) Severability. Whenever
possible, each provision of this Agreement shall be interpreted in such a manner
as to be effective and valid under applicable law but if any provision of this
Agreement is held to be invalid, illegal or unenforceable under any applicable
law or rule, the validity, legality and enforceability of the other provision of
this Agreement will not be affected or impaired thereby.

     (d) Successors and
Assigns. This Agreement shall be binding upon and inure to the benefit of
the parties hereto and their respective heirs, personal representatives,
successors and assigns.

     (e) Modification, Amendment,
Waiver or Termination. No provision of this Agreement may be modified,
amended, waived or terminated except by an instrument in writing signed by the
parties to this Agreement. No course of dealing between the parties will modify,
amend, waive or terminate any provision of this Agreement or any rights or
obligations of any party under or by reason of this Agreement. No delay on the
part of ICON in the exercise of any right or remedy under this Agreement shall
operate as a waiver thereof, and no single or partial exercise by ICON of any
right or remedy under this Agreement shall preclude other or further exercise
thereof or the exercise of any other right or remedy. No waiver by ICON of any
right or remedy under this Agreement shall be deemed to be or construed as a
further or continuing waiver of such right or remedy or as a waiver of any other
right or remedy.

     (f) Notices. All notices,
consents, requests, instructions, approvals or other communications provided for
herein shall be in writing and delivered by personal delivery, overnight
courier, mail or electronic facsimile addressed to the receiving party at the
address set forth herein. All such communications shall be effective when
received.

To: XENO and the Pledgors 
Elliot
Lebowitz, CEO 
American Xeno, Inc.
143 Gardner Road 
Brookline,
Massachusetts 02445 
Fax: (617) 734-6207

with copy to: 
Christopher Dieterich

Dieterich & Associates
11300 West Olympic Boulevard, Suite 800

Los Angeles, California 90064 
Fax: (310) 312-6680

To: ICON
Icon Development, Inc.

Wayne Smith 
1235 Quayside Drive, Suite 703
New Westminster, British
Columbia V3M 6J5 
Canada 
Fax: (604) 684-4601

with copy to: 
Thomas M. Rose

Troutman Sanders LLP
222 Central Park Avenue, Suite 2000 
Virginia
Beach, Virginia 23462

3

     Fax: (757) 687-1529

Any party may change the address set forth above by notice to
each other party given as provided herein.

     (g) Headings. The headings
and any table of contents contained in this Agreement are for reference purposes
only and shall not in any way affect the meaning or interpretation of this
Agreement.

     (h) Governing Law. ALL
MATTERS RELATING TO THE INTERPRETATION, CONSTRUCTION, VALIDITY AND ENFORCEMENT
OF THIS AGREEMENT SHALL BE GOVERNED BY THE INTERNAL LAWS OF THE STATE OF NEVADA,
WITHOUT GIVING EFFECT TO ANY CHOICE OF LAW PROVISIONS THEREOF.

     (i) Third-Party Benefit.
Nothing in this Agreement, express or implied, is intended to confer upon any
other person any rights, remedies, obligations or liabilities of any nature
whatsoever.

     (j) Remedies Cumulative.
All rights and remedies of ICON under this Agreement are cumulative and are in
addition to, but not in limitation of, any rights or remedies which it may have
under applicable law.

4

     IN WITNESS WHEREOF, the
parties hereto have executed this Agreement as of the date set forth in the
first paragraph.

/s/ Elliot Lebowitz 
Elliot Lebowitz

/s/ Ken Swaisland 
Ken Swaisland

AMERICAN XENO, INC.

By: /s/ Elliot Lebowitz 
Name: Elliot Lebowitz

Title: Chief Executive Officer

ICON DEVELOPMENT, INC.

By: /s/ Wayne Smith 

  Name: Wayne Smith 

  Title: Secretary and Treasurer

5AMENDMENT NO. 1 TO RIGHTS AGREEMENT

    Exhibit
      4.1

     

    

    AMENDMENT
      NO. 1 TO RIGHTS AGREEMENT

    

    This
      Amendment No. 1 (“Amendment”) dated April 23, 2007 to Rights Agreement dated
      August 30, 2002 (“Agreement”), between Centene Corporation a Delaware
      corporation (the “Company”), and Mellon Investor Services LLC, a New Jersey
      limited liability company, as Rights Agent (the “Rights Agent”). Capitalized
      terms used herein and not otherwise defined herein shall have the meanings
      given
      to such terms in the Agreement.

    

    WHEREAS,
      the Board of Directors of the Company has determined it is in the best interests
      of the Company and its shareholders to increase the Purchase Price;

    

    WHEREAS,
      as a result of previous automatic adjustments under the Agreement for the
      Company’s stock splits in July 2003 and December 2004 (effected in the form of
      stock dividends), each share of the Company’s common stock par
      value
      $0.001 per share (“Common Stock”) is currently associated with one-third of a
      Right which would entitle its registered holder to purchase from the Company
      (or
      receive the value of) one three-thousandth of a share of the Company’s Series A
      Junior Participating Preferred Stock (“Preferred Stock”), subject to adjustment
      as provided in the Agreement;

    

    WHEREAS,
      because of the nature of the Preferred Stock’s dividend, liquidation and voting
      rights, the value of one three-thousandth of a share of the Preferred Stock
      purchasable upon exercise of each one-third of a Right should approximate the
      value of one share of Common Stock;

    

    WHEREAS,
      the Board of Directors wants the Purchase Price to be expressed in a fashion
      that is understandable in relation to the one-third of a Right associated with
      each share of Common Stock, and to make such other changes as are necessary
      or
      appropriate to accommodate such change, without otherwise affecting the
      operation and implementation of the Rights Agreement; 

    

    NOW,
      THEREFORE, in consideration of the premises and the mutual agreements herein
      set
      forth, the parties hereby agree as follows:

    

    
      	1.  	
              The
                last sentence of Section 4(a) is hereby replaced in its entirety
                with the
                following: 

            

    

    

    Subject
      to the provisions of Sections 7, 11 and 22, the Rights Certificates, whenever
      distributed, shall entitle the holders thereof to purchase such number of one
      one-thousandths of a share of Preferred Stock as shall be set forth therein
      at
      the price set forth therein (such exercise price expressed per one
      three-thousandth of a share of Preferred Stock being referred to herein as
      the
      "Purchase Price"), but the amount and type of securities purchasable upon the
      exercise of each Right and the Purchase Price shall be subject to adjustment
      as
      provided herein.

    

    
      	2.  	
              Section
                7(b) of the Agreement is hereby replaced in its entirety with the
                following:

            

    

    

    “(b)
      The
      Purchase Price for each one three-thousandth of a share of Preferred Stock
      shall
      be $95.00 and shall be subject to adjustment from time to time as provided
      in
      Sections 11 and 13(a) and shall be payable in lawful money of the United States
      of America in accordance with paragraph (c) below.”

     

    

    
      
        
           

        

        
           

          
            

          

        

        
           

        

      

    

    

    Section
      7(c) of the Agreement is hereby replaced in its entirety with the
      following:

    

    “(c)
      Upon
      receipt of a Rights Certificate representing exercisable Rights, with the form
      of election to purchase and the certificate duly executed, accompanied by
      payment, with respect to each one-third of a Right so exercised, of the Purchase
      Price per one three-thousandth of a share of Preferred Stock (or other shares,
      securities, cash or other assets, as the case may be) to be purchased and an
      amount equal to any applicable tax or governmental charge, the Rights Agent
      shall, subject to Section 20(k), thereupon promptly (i) (A) requisition from
      any
      transfer agent of the shares of Preferred Stock (or make available, if the
      Rights Agent is the transfer agent for such shares) certificates for the total
      number of one three-thousandths of a share of Preferred Stock to be purchased
      and the Company hereby authorizes its transfer agent to comply with such
      requests, or (B) if the Company shall have elected to deposit the total number
      of shares of Preferred Stock issuable upon exercise of the Rights hereunder
      with
      a depositary agent, requisition from the depositary agent depositary receipts
      representing such number of one three-thousandths of a share of Preferred Stock
      as are to be purchased (in which case certificates for the shares of Preferred
      Stock represented by such receipts shall be deposited by the transfer agent
      with
      the depositary agent) and the Company hereby directs the depositary agent to
      comply with such requests, (ii) requisition from the Company the amount of
      cash,
      if any, to be paid in lieu of fractional shares in accordance with Section
      14,
      (iii) after receipt of such certificates or depositary receipts, cause the
      same
      to be delivered to or upon the order of the registered holder of such Rights
      Certificate, registered in such name or names as may be designated by such
      holder, and (iv) after receipt thereof, deliver such cash, if any, to or upon
      the order of the registered holder of such Rights Certificate. The payment
      of
      the Purchase Price (as such amount may be reduced pursuant to Section
      11(a)(iii)) may be made in cash or by certified bank check or money order
      payable to the order of the Company. In the event that the Company is obligated
      to issue other securities (including Common Stock) of the Company, pay cash
      and/or distribute other property pursuant to Section 11(a), the Company shall
      make all arrangements necessary so that such other securities, cash and/or
      other
      property are available for distribution by the Rights Agent, if and when
      necessary to comply with this Agreement.”

    

    
      	3.  	
              Section
                11(a) of the Agreement is hereby replaced in its entirety with the
                following:

            

    

    

    “(a)(i)
      In the event the Company shall at any time after the date of this Agreement
      (A) declare a dividend on the Preferred Stock payable in shares of
      Preferred Stock, (B) subdivide the outstanding Preferred Stock, (C) combine
      the outstanding Preferred Stock into a smaller number of shares, or (D) issue
      any shares of its capital stock in a reclassification of the Preferred Stock
      (including any such reclassification in connection with a consolidation or
      merger in which the Company is the continuing or surviving corporation), except
      as otherwise provided in this Section 11(a) and Section 7(e), the Purchase
      Price
      in effect at the time of the record date for such dividend or of the effective
      date of such subdivision, combination or reclassification, and the number and
      kind of shares of Preferred Stock or capital stock, as the case may be, issuable
      on such date, shall be proportionately adjusted so that the holder of any
      one-third of a Right exercised after such time shall be entitled to receive,
      upon payment of the Purchase Price then in effect, the aggregate number and
      kind
      of shares of Preferred Stock or capital stock, as the case may be, which, if
      such one-third of a Right had been exercised immediately prior to such date
      and
      at a time when the Preferred Stock transfer books of the Company were open,
      he
      would have owned upon such exercise and been entitled to receive by virtue
      of
      such dividend, subdivision, combination
      or reclassification. If an event occurs that would require an adjustment under
      both this Section 11(a)(i) and Section 11(a)(ii), the adjustment provided for
      in
      this Section 11(a)(i) shall be in addition to, and shall be made prior to,
      any
      adjustment required pursuant to Section 11(a)(ii).

     

    

    
      
        
           

        

        
           

          
            

          

        

        
           

        

      

    

    

     

    (ii)
      Subject to Section 24 of this Agreement, in the event that any Person, alone
      or
      together with its Affiliates or Associates, becomes an Acquiring Person (other
      than pursuant to a Permitted Offer), then, promptly following the first
      occurrence of such event, proper provision shall be made so that each holder
      of
      one-third of a Right (except as provided below and in Section 7(e)) shall
      thereafter have the right to receive (subject to the last sentence of Section
      23(a)), upon exercise thereof at the then current Purchase Price in accordance
      with the terms of this Agreement, in lieu of Preferred Stock, such number of
      shares of Common Stock of the Company that equals the result obtained by (x)
      multiplying the then current Purchase Price by the then number of one
      three-thousandths of a share of Preferred Stock for which one-third of a Right
      was exercisable immediately prior to the first occurrence of a Section11(a)(ii)
      Event, and (y) dividing that product (which, following such first occurrence,
      shall thereafter be referred to as the "Purchase Price" for each one-third
      of a
      Right and for all purposes of this Agreement) by 50% of the current market
      price
      (determined pursuant to Section 11(d)) per share of Common Stock on the date
      of
      such first occurrence (such number of shares, the "Adjustment
      Shares").

     

    (iii)
      In
      the event that the number of shares of Common Stock that are authorized by
      the
      Company's Certificate of Incorporation but not outstanding or reserved for
      issuance for purposes other than upon exercise of the Rights are not sufficient
      to permit the exercise in full of the Rights in accordance with the foregoing
      subparagraph (ii)of this Section 11(a), the Company shall: (A) determine the
      excess of (1) the value of the Adjustment Shares issuable upon the exercise
      of
      one-third of a Right (the "Current Value") over (2) the Purchase Price (such
      excess, the "Spread"), and (B) with respect to each one-third of a Right, make
      adequate provision to substitute for the Adjustment Shares, upon payment of
      the
      applicable Purchase Price, (1) cash, (2) a reduction in the Purchase Price,
      (3)
      Common Stock or other equity securities of the Company (including shares, or
      units of shares, of preferred stock that the Board has deemed to have the same
      value as shares of Common Stock (such shares of preferred stock, "common stock
      equivalents")), (4) debt securities of the Company, (5) other assets, or (6)
      any
      combination of the foregoing, having an aggregate value equal to the Current
      Value, where such aggregate value has been determined by the Board based upon
      the advice of a nationally recognized investment banking firm selected by the
      Board; provided, however, if the Company shall not have made adequate provision
      to - deliver value pursuant to clause (B) above within thirty days following
      the
      later of (x) the first occurrence of a Section 11(a)(ii) Event and (y) the
      date
      on which the Company's right of redemption pursuant to Section 23(a) expires
      (the later of (x) and (y) being referred to herein as the “Section 11(a)(ii)
      Trigger Date"), then the Company shall be obligated to deliver, upon the
      surrender for exercise of each one-third of a Right and without requiring
      payment of the Purchase Price, shares of Common Stock (to the extent available)
      and then, if necessary, cash, which shares and/or cash have an aggregate value
      equal to the Spread. If the Board shall determine in good faith that it is
      likely that sufficient additional shares of Common Stock could be authorized
      for
      issuance upon exercise in full of the Rights, the thirty day period set forth
      above may be extended to the extent necessary, but not more than ninety (90)
      days after the Section 11(a)(ii) Trigger Date, in order that the Company may
      seek shareholder approval for the authorization of such additional shares (such
      period, as it may

     

    

    
      
        
           

        

        
           

          
            

          

        

        
           

        

      

    

     

        be
      extended,
      the “Substitution Period"). To the extent that the Company determines that some
      action need be taken pursuant to the first and/or second sentences of this
      Section 11(a)(iii), the Company (x) shall provide, subject to Section 7(e),
      that
      such action shall apply uniformly to all outstanding Rights, and (y) may suspend
      the exercisability of the Rights until the expiration of the Substitution Period
      in order to seek any authorization of additional shares and/or to decide the
      appropriate form of distribution to be made pursuant to such first sentence
      and
      to determine the value thereof. In the event of any such suspension, the Company
      shall promptly notify the Rights Agent of such suspension and shall issue a
      public announcement stating that the exercisability of the Rights has been
      temporarily suspended, as well as a public announcement-13-(with prompt notice
      thereof to the Rights Agent) at such time as the suspension is no longer in
      effect. For purposes of this Section11(a)(iii), the value of the Common Stock
      shall be the current market price (as determined pursuant to Section 11(d))
      per
      share of the Common Stock on the Section 11(a)(ii) Trigger Date and the value
      of
      any "common stock equivalent" shall be deemed to have the same value as the
      Common Stock on such date.”

     

    
      	4.  	
              Sections
                11(g) and (h) of the Agreement are hereby replaced in its entirety
                with
                the following:

            

    

    

    “(g)
      Each
      one-third of a Right originally issued by the Company subsequent to any
      adjustment made to the Purchase Price hereunder shall evidence the right to
      purchase, at the adjusted Purchase Price, the number of one three-thousandths
      of
      a share of Preferred Stock purchasable from time to time hereunder upon exercise
      of one-third of a Right, all subject to further adjustment as provided
      herein.

    

    (h)
      Unless the Company shall have exercised its election as provided in Section
      11(i), upon each adjustment of the Purchase Price as a result of the
      calculations made in Sections 11(b) and (c), each one-third of a Right
      outstanding immediately prior to the making of such adjustment shall thereafter
      evidence the right to purchase, at the adjusted Purchase Price, that number
      of
      one three-thousandths of a share of Preferred Stock (calculated to the nearest
      ten-millionth) obtained by (i) multiplying (x) the number of one
      three-thousandths of a share covered by one-third of a Right immediately prior
      to this adjustment, by (y) the Purchase Price in effect immediately prior to
      such adjustment of the Purchase Price, and (ii) dividing the product so obtained
      by the Purchase Price in effect immediately after such adjustment of the
      Purchase Price.” 

     

    
      	5.  	
              Section
                13(a) of the Agreement is hereby replaced in its entirety with the
                following:

            

    

    

    “(a)
      In
      the event that, at any time after a Person has become an Acquiring Person,
      (x)
      the Company shall consolidate with, or merge with and into, any other Person
      (other than a Subsidiary of the Company in a transaction that complies with
      Section 11(o)), and the Company shall not be the continuing or surviving
      corporation of such consolidation or merger, (y) any Person (other than a
      Subsidiary of the Company in a transaction that complies with Section 11(o))
      shall consolidate with, -18- or merge with or into, the Company, and the Company
      shall be the continuing or surviving corporation of such consolidation or merger
      and, in connection with such consolidation or merger, all or part of the
      outstanding shares of Common Stock shall be changed into or exchanged for stock
      or other securities of any other Person or cash or any other property, or (z)
      the Company shall sell or otherwise transfer (or one or more of its Subsidiaries
      shall sell or otherwise transfer), in one transaction or a series of related
      transactions, assets or earning power aggregating more than 50% of the assets
      or
      earning power of the Company and its Subsidiaries (taken as a whole) to any
      Person or Persons (other than the Company or any Subsidiary of the Company
      in
      one or more transactions each of which complies with Section 11(o)), then,
      and
      in each such case and except as contemplated by Section 13(d), proper provision
      shall be made so that: (i) each holder of one-third of a Right, except as
      provided in Section 7(e), shall thereafter have the right to receive, upon
      the
      exercise thereof at the then current Purchase Price in accordance with the
      terms
      of this Agreement, such number of validly authorized and issued, fully paid,
      non-assessable and freely tradable shares of Common Stock of the Principal
      Party
      (as such term is hereinafter defined), which shall not be subject to any liens,
      encumbrances, rights of first refusal or other adverse claims, as shall be
      equal
      to the result obtained by (1) multiplying the then current Purchase Price by
      the
      number of one three-thousandths of a share of Preferred Stock for which
      one-third of a Right is exercisable immediately prior to the first occurrence
      of
      a Section 13 Event (or, if a Section 11(a)(ii) Event has occurred prior to
      the
      first occurrence of a Section 13 Event, multiplying the number of such one
      three-thousandths of a share for which one-third of a Right was exercisable
      immediately prior to the first occurrence of a Section 11(a)(ii) Event by the
      Purchase Price in effect immediately prior to such first occurrence), and (2)
      dividing that product (which, following the first occurrence of a Section 13
      Event, shall be referred to as the "Purchase Price" for each one-third of a
      Right and for all purposes of this Agreement) by 50% of the current market
      price
      (determined pursuant to Section 11(d)(i)) per share of the Common Stock of
      such
      Principal Party on the date of consummation of such Section 13 Event; (ii)
      such
      Principal Party shall thereafter be liable for, and shall assume, by virtue
      of
      such Section 13 Event, all the obligations and duties of the Company pursuant
      to
      this Agreement; (iii) the term "Company" shall thereafter be deemed to refer
      to
      such Principal Party, it being specifically intended that, subject to clause
      (v)
      below, the provisions of Section 11 shall apply only to such Principal Party
      following the first occurrence of a Section 13 Event; (iv) such Principal Party
      shall take such steps (including, but not limited to, the reservation of a
      sufficient number of shares of its Common Stock) in connection with the
      consummation of any such transaction as may be necessary to assure that the
      provisions hereof shall thereafter be applicable, as nearly as reasonably may
      be, in relation to its shares of Common Stock thereafter deliverable upon the
      exercise of the Rights; and (v) the provisions of Section 11(a)(ii) shall be
      of
      no effect following the first occurrence of any Section 13 Event.”

    

    
      	6.  	
              It
                is understood and agreed that the Agreement shall be interpreted
                so as to
                give effect to the intent of the Recitals of this
                Amendment.

            

    

    

    
      	7.  	
              It
                is understood and agreed that each whole Right, following the changes
                effected by this Amendment, remains exercisable for one one-thousandth
                of
                a share of Preferred Stock.

            

    

    

    IN
      WITNESS WHEREOF, the parties hereto have caused this Amendment to be duly
      executed and their respective corporate seals to be hereunto affixed and
      attested, all as of the day and year first above written.

    

    CENTENE
      CORPORATION

    

    

    

    

    By:_/s/
      MICHAEL
      F. NEIDORFF_________________________

    Michael
      F. Neidorff

    President
      and Chief Executive Officer

    Attest:

    

    

    By:_/s/
      KEITH
      WILLIAMSON_______________________

    Keith
      Williamson

    Senior
      Vice President, Secretary and

    General
      Counsel

    MELLON
      INVESTOR SERVICES LLC,

    AS
      RIGHTS
      AGENT

    

    

    BY:
      _/s/ JANE
      A. MARTEN___________________

    Name:
      Jane A. Marten

    Title:
      Asst. Vice President

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00122-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00122-of-00352.parquet"}]]