Document:

EXHIBIT 10.28
                                                                   -------------

                               ADDENDUM NUMBER ONE
                                       TO
                                RAMESH C. TRIVEDI
                            EMPLOYMENT CONTRACT DATED
                                December 8, 1995

Pursuant to actions taken by the Compensation Committee of the Board of
Directors of Integrated Surgical Systems, Inc. on December 18, 1997 and in the
months thereafter concluding on March 12, 1998, the following adjustments are to
be made in Dr. Trivedi's agreement.

     1.   Base Salary is to be increased by 6% from $22,000 per month to $23,320
          per month effective December 1, 1997.

     2.   Incentive base for 1998 is increased from $80,000 to $100,000. The
          actual payout amount will be based on the achievement against the 1998
          business plan agreed to by the board, with the calculation algorithm
          similar to the one used in 1997, but to be determined in fact at a
          later date.

     3,   Stock options for 100,000 shares are issued to Dr. Trivedi with a
          grant price of $4.75, the price of the stock on February 19, 1998. Of
          the 100,000 shares, the amount of shares that shall be immediately
          vested shall be 28,125. The balance of the shares, 71,875 shall vest
          ratably over the 48 month period beginning February 19, 1998.

     4.   Severance pay is currently set at 12 months in the event of
          termination of employment. As of this amendment, severance pay upon
          termination will be 18 months of Dr. Trivedi's base pay.

This amendment is incorporated and becomes a part of the Employment Contract
dated December 8, 1995. All other terms and conditions, not modified by this
agreement remain the same.

/s/ Ramesh C. Trivedi
----------------------------------                   ---------------------------
Ramesh C. Trivedi, President & CEO                   James C. McGroddy, Chairman

Date:  March 31, 1998                                Date:
       ---------------------------                         ---------------------EXHIBIT 10.29
                                                                   -------------

                        INTEGRATED SURGICAL SYSTEMS, INC.
                            1850 Research Park Drive
                             Davis, California 95616

                                February 14, 2003

Mr. Charles J. Novak
8163 Parus Way
Granite Bay, California 95746

Dear Chuck:

     In connection with your letter of employment dated July 15, 2002, a copy of
which is attached hereto, we are furnishing you with this letter agreement to
establish the terms and conditions of your employment with the Company as set
forth below.

     1. RESPONSIBILITIES. You shall serve as and perform the functions of Chief
Financial Officer of the Company and shall perform such other duties and
functions as may be assigned to you from time to time by the Company's Board of
Directors (the "Board of Directors") as are reasonable and customary to your
position. During your employment with the Company, you shall devote substantial
working time to the business of the Company.

     2. COMPENSATION. The Company shall pay you for your services hereunder, and
you shall accept, (i) a salary of $10,000 per month ("Base Salary") and (ii)
such incentive compensation as shall be determined from time to time by the
Board of Directors of the Company. Your Base Salary shall be paid in equal
installments on a basis consistent with the Company's payroll practices for
senior executives.

     3. BENEFITS. During your employment with the Company, you shall be entitled
to participate in any pension plan, group life insurance plan, health and
hospitalization insurance plan, and medical services plan and other similar
plans, now or hereafter existing, generally afforded by the Company to other
senior executives.

     4. EXPENSES. During your employment with the Company, the Company shall
reimburse you for all reasonable and necessary travel expenses and other
disbursements incurred by you on behalf of the Company in the performance of
your duties hereunder, assuming you have received prior approval by the Company
to the extent possible, consistent with the Company's practice for such travel
expenses and disbursements or written policy in effect with respect to the
reimbursement of expenses to senior executives of the Company. Such expenses
shall be reimbursed only upon presentation of paid receipts and/or original
invoices and such other information as shall be required for tax purposes.

<PAGE>

     5. CONFIDENTIAL INFORMATION. You recognize that you have and will continue
to have access to secret and confidential information regarding the Company and
its subsidiaries and affiliated companies, including but not limited to, all
trade secrets, proprietary information, formulae, budgets, projections, reports,
plans, proposals, financial information, customer and vendor lists, proposed
services, marketing plans, know how and other information, and strategies and
ideas, belonging to or relating to the business of the Company and its
subsidiaries and affiliated companies (the "Confidential Information"). You
acknowledge that such Confidential Information is of great value to the Company,
is the sole property of the Company, and has been and will be acquired by you in
confidence. In consideration of the obligations undertaken by the Company
herein, you shall not at any time, during or after your employment hereunder,
reveal, divulge or make known to others or use any such Confidential
Information. The provisions of this Section 5 shall survive your termination of
employment hereunder.

     6. TERM. Your employment with the Company is for no specified period and
constitutes at-will employment. As a result, you are free to resign at any time,
for any reason or for no reason. Similarly, the Company is free to conclude its
employment relationship with you at any time, with or without cause.

     7. SEVERANCE PAY

          (A) Termination In the event you are terminated by the Company for
reasons other than for Cause (as defined below), you will be entitled to receive
severance pay of your Base Salary for a period of three months from the date of
termination, payable in equal monthly installments.

          For purposes of this agreement, the term "Cause" shall mean (i) your
conviction (including a conviction on a nolo contendere plea) of a felony or
misdemeanor (other than minor traffic offenses); (ii) neglect or failure to
perform your duties as an employee of the Company in any material respect; (iii)
any grossly negligent act having the effect of injuring your reputation or the
reputation of business of the Company in any material respect; (iv) repeated
willful violations of lawful policies of the Company; or (v) any other
malfeasance, misfeasance or nonfeasance by you in any material respect relative
to or in connection with the performance of your duties as an employee of the
Company.

          (B) Business Transaction. In the event of any consolidation or merger
of the Company with or into another entity ("Entity"), or the sale of all or
substantially all of the assets of the Company to another Entity (a
Transaction"), you are unable to reach a reasonable agreement of employment with
the Entity, you shall be entitled to receive severance pay of your Base Salary
for a period of six months from the date of termination, payable in equal
monthly installments, provided, however, you agree to make reasonable efforts to
assist the Entity in its transition in connection with the Transaction for a
reasonable period of time.

                                       2

<PAGE>

     If you are in agreement with the foregoing, please sign and return to the
Company one copy of this letter agreement, which will constitute our agreement
with respect to the subject matter of this letter.

                                Integrated Surgical Systems, Inc.

                                By:   /s/ Ramesh C. Trivedi
                                      ----------------------------------------
                                          Ramesh C. Trivedi,
                                          Chief Executive Officer and President

 Accepted and Agreed this
 14th day of February, 2003.

 /s/ Charles J. Novak
---------------------
 Charles J. Novak

                                       3EXHIBIT 10.30
                                                                   -------------

                        INTEGRATED SURGICAL SYSTEMS, INC.
                            1850 Research Park Drive
                             Davis, California 95616

                                February 14, 2003

Mr. Leland Witherspoon
3329 Marina Cove Circle
Elk Grove, California 95758

Dear Leland:

     In connection with your employment with the Company, we are furnishing you
with this letter agreement to establish the terms and conditions of your
employment with the Company as set forth below.

     1. RESPONSIBILITIES. You shall serve as and perform the functions of Vice
President, Engineering of the Company and shall perform such other duties and
functions as may be assigned to you from time to time by the Company's Board of
Directors (the "Board of Directors") as are reasonable and customary to your
position. During your employment with the Company, you shall devote substantial
working time to the business of the Company.

     2. COMPENSATION. The Company shall pay you for your services hereunder, and
you shall accept, (i) a salary of $11,883.34 per month ("Base Salary") and (ii)
such incentive compensation as shall be determined from time to time by the
Board of Directors of the Company. Your Base Salary shall be paid in equal
installments on a basis consistent with the Company's payroll practices for
senior executives.

     3. BENEFITS. During your employment with the Company, you shall be entitled
to participate in any pension plan, group life insurance plan, health and
hospitalization insurance plan, and medical services plan and other similar
plans, now or hereafter existing, generally afforded by the Company to other
senior executives.

     4. EXPENSES. During your employment with the Company, the Company shall
reimburse you for all reasonable and necessary travel expenses and other
disbursements incurred by you on behalf of the Company in the performance of
your duties hereunder, assuming you have received prior approval by the Company
to the extent possible, consistent with the Company's practice for such travel
expenses and disbursements or written policy in effect with respect to the
reimbursement of expenses to senior executives of the Company. Such expenses
shall be reimbursed only upon presentation of paid receipts and/or original
invoices and such other information as shall be required for tax purposes.

<PAGE>

     5. CONFIDENTIAL INFORMATION. You recognize that you have and will continue
to have access to secret and confidential information regarding the Company and
its subsidiaries and affiliated companies, including but not limited to, all
trade secrets, proprietary information, formulae, budgets, projections, reports,
plans, proposals, financial information, customer and vendor lists, proposed
services, marketing plans, know how and other information, and strategies and
ideas, belonging to or relating to the business of the Company and its
subsidiaries and affiliated companies (the "Confidential Information"). You
acknowledge that such Confidential Information is of great value to the Company,
is the sole property of the Company, and has been and will be acquired by you in
confidence. In consideration of the obligations undertaken by the Company
herein, you shall not at any time, during or after your employment hereunder,
reveal, divulge or make known to others or use any such Confidential
Information. The provisions of this Section 5 shall survive your termination of
employment hereunder.

     6. TERM. Your employment with the Company is for no specified period and
constitutes at-will employment. As a result, you are free to resign at any time,
for any reason or for no reason. Similarly, the Company is free to conclude its
employment relationship with you at any time, with or without cause.

     7. SEVERANCE PAY

          (A) Termination In the event you are terminated by the Company for
reasons other than for Cause (as defined below), you will be entitled to receive
severance pay of your Base Salary for a period of three months from the date of
termination, payable in equal monthly installments.

          For purposes of this agreement, the term "Cause" shall mean (i) your
conviction (including a conviction on a nolo contendere plea) of a felony or
misdemeanor (other than minor traffic offenses); (ii) neglect or failure to
perform your duties as an employee of the Company in any material respect; (iii)
any grossly negligent act having the effect of injuring your reputation or the
reputation of business of the Company in any material respect; (iv) repeated
willful violations of lawful policies of the Company; or (v) any other
malfeasance, misfeasance or nonfeasance by you in any material respect relative
to or in connection with the performance of your duties as an employee of the
Company.

          (B) Business Transaction. In the event of any consolidation or merger
of the Company with or into another entity ("Entity"), or the sale of all or
substantially all of the assets of the Company to another Entity (a
Transaction"), you are unable to reach a reasonable agreement of employment with
the Entity, you shall be entitled to receive severance pay of your Base Salary
for a period of six months from the date of termination, payable in equal
monthly installments, provided, however, you agree to make reasonable efforts to
assist the Entity in its transition in connection with the Transaction for a
reasonable period of time.

                                       2

<PAGE>

          If you are in agreement with the foregoing, please sign and return to
the Company one copy of this letter agreement, which will constitute our
agreement with respect to the subject matter of this letter.

                                    Integrated Surgical Systems, Inc.

                                    By:  Ramesh C. Trivedi
                                         Ramesh C. Trivedi,
                                         Chief Executive Officer and President

 Accepted and Agreed this
 14th day of February, 2003.

 /s/ Leland Witherspoon
 ----------------------
 Leland Witherspoon

                                       3

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